Pathogenicity Island: cag PAI


• General information

Name : cag PAI
Host strain : Helicobacter pylori J99
Function : Translocation of CagA, Type IV secretion system, stimulation of IL-8 synthesis
Insertion site : murI (glutamate racemase)


• GenBank accessions: 1 records

1) NC_000921_P1 (38195 bp)

    Definition : cag pathogenicity island (cag PAI), (510500..548694) bp from NC_000921, Helicobacter pylori J99 chromosome, complete genome.

    Publication :
    - Merrell,D.S., Thompson,L.J., Kim,C.C., Mitchell,H., Tompkins,L.S., Lee,A. and Falkow,S., "Growth phase-dependent response of Helicobacter pylori to iron starvation", Infect. Immun. 71 (11), 6510-6525 (2003) PUBMED 14573673.

    - Alm,R.A., Ling,L.-S.L., Moir,D.T., King,B.L., Brown,E.D., Doig,P.C., Smith,D.R., Noonan,B., Guild,B.C., deJonge,B.L., Carmel,G., Tummino,P.J., Caruso,A., Uria-Nickelsen,M., Mills,D.M., Ives,C., Gibson,R., Merberg,D., Mills,S.D., Jiang,Q., Taylor,D.E., Vov, "Genomic-sequence comparison of two unrelated isolates of the human gastric pathogen Helicobacter pylori", Nature 397 (6715), 176-180 (1999) PUBMED 9923682.

    - Alm,R.A., Ling,L.-S.L., Moir,D.T., King,B.L., Brown,E.D., Doig,P.C., Smith,D.R., Noonan,B., Guild,B.C., deJonge,B.L., Carmel,G., Tummino,P.J., Caruso,A., Uria-Nickelsen,M., Mills,D.M., Ives,C., Gibson,R., Merberg,D., Mills,S.D., Jiang,Q., Taylor,D.E., Vov, "Direct Submission", Submitted (13-SEP-2001) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA.

    - King,B.L., Alm,R.A. and Trust,T.J., "Direct Submission", Submitted (12-JAN-1999) Astra Research Center Boston, 128 Sidney Street, Cambridge, MA 02139, USA.


      






• PAI-like regions homologous to this PAI (genomes and locations)

NC_017374 (Helicobacter pylori 2017): 0.5 Mb
NC_017381 (Helicobacter pylori 2018): 0.5 Mb
NC_000915 (Helicobacter pylori 26695): 0.5 Mb
NC_018939 (Helicobacter pylori 26695): 0.5 Mb
NC_017360 (Helicobacter pylori 35A): 1.0 Mb
NC_017382 (Helicobacter pylori 51): 0.8 Mb
NC_017354 (Helicobacter pylori 52): 0.8 Mb
NC_017375 (Helicobacter pylori 83): 0.9 Mb
NC_017357 (Helicobacter pylori 908): 0.5 Mb
NC_014256 (Helicobacter pylori B8): 0.7 Mb
NC_017358 (Helicobacter pylori Cuz20): 0.6 Mb
NC_017063 (Helicobacter pylori ELS37): 0.8 Mb
NC_017368 (Helicobacter pylori F16): 0.8 Mb
NC_017365 (Helicobacter pylori F30): 0.8 Mb
NC_017366 (Helicobacter pylori F32): 0.5 Mb
NC_017367 (Helicobacter pylori F57): 0.6 Mb
NC_011333 (Helicobacter pylori G27): 0.5 Mb
NC_017371 (Helicobacter pylori Gambia94/24): 0.5 Mb
NC_008086 (Helicobacter pylori HPAG1): 0.5 Mb
NC_017733 (Helicobacter pylori HUP-B14): 0.8 Mb
NC_017372 (Helicobacter pylori India7): 0.8 Mb
NC_000921 (Helicobacter pylori J99): 0.5 Mb
NC_017362 (Helicobacter pylori Lithuania75): 0.5 Mb
NC_020508 (Helicobacter pylori OK113): 0.6 Mb
NC_020509 (Helicobacter pylori OK310): 0.8 Mb
NC_011498 (Helicobacter pylori P12): 0.5 Mb
NC_017742 (Helicobacter pylori PeCan18): 0.5 Mb
NC_014555 (Helicobacter pylori PeCan4): 0.5 Mb
NC_017378 (Helicobacter pylori Puno120): 0.5 Mb
NC_017379 (Helicobacter pylori Puno135): 0.5 Mb
NC_018937 (Helicobacter pylori Rif1): 0.5 Mb
NC_018938 (Helicobacter pylori Rif2): 0.5 Mb
NC_017376 (Helicobacter pylori Santal49): 0.5 Mb
NC_017359 (Helicobacter pylori Sat464): 0.8 Mb
NC_017741 (Helicobacter pylori Shi112): 0.9 Mb
NC_017740 (Helicobacter pylori Shi169): 0.5 Mb
NC_017739 (Helicobacter pylori Shi417): 0.5 Mb
NC_010698 (Helicobacter pylori Shi470): 0.8 Mb
NC_014560 (Helicobacter pylori SJM180): 0.5 Mb
NC_021215 (Helicobacter pylori UM032): 0.9 Mb
NC_021217 (Helicobacter pylori UM037): 0.8 Mb
NC_021218 (Helicobacter pylori UM066): 1.0 Mb
NC_021882 (Helicobacter pylori UM298): 1.5 Mb
NC_021216 (Helicobacter pylori UM299): 0.4 Mb
NC_017355 (Helicobacter pylori v225d): 0.5, 0.5 Mb
NC_017926 (Helicobacter pylori XZ274): 0.9 Mb