Pathogenicity Island: cag PAI


• General information

Name : cag PAI
Host strain : Helicobacter pylori 26695
Function : Translocation of CagA, Type IV secretion system, stimulation of IL-8 synthesis
Insertion site : glr (glutamate racemase)


• GenBank accessions: 1 records

1) NC_000915_P1 (38023 bp)

    Definition : cag pathogenicity island (cag PAI), (547328..585350) bp from NC_000915, Helicobacter pylori 26695 chromosome, complete genome.

    Publication :
    - Raymond,J., Thiberge,J.M., Kalach,N., Bergeret,M., Dupont,C., Labigne,A. and Dauga,C., "Using macro-arrays to study routes of infection of Helicobacter pylori in three families", PLoS ONE 3 (5), E2259 (2008) PUBMED 18493595 REMARK Publication Status: Online-Only.

    - Wen,Y., Marcus,E.A., Matrubutham,U., Gleeson,M.A., Scott,D.R. and Sachs,G., "Acid-adaptive genes of Helicobacter pylori", Infect. Immun. 71 (10), 5921-5939 (2003) PUBMED 14500513.

    - Marais,A., Mendz,G.L., Hazell,S.L. and Megraud,F., "Metabolism and genetics of Helicobacter pylori: the genome era", Microbiol. Mol. Biol. Rev. 63 (3), 642-674 (1999) PUBMED 10477311.

    - Tomb,J.-F., White,O., Kerlavage,A.R., Clayton,R.A., Sutton,G.G., Fleischmann,R.D., Ketchum,K.A., Klenk,H.P., Gill,S., Dougherty,B.A., Nelson,K., Quackenbush,J., Zhou,L., Kirkness,E.F., Peterson,S., Loftus,B., Richardson,D., Dodson,R., Khalak,H.G., Glodek,, "The complete genome sequence of the gastric pathogen Helicobacter pylori", Nature 388 (6642), 539-547 (1997) PUBMED 9252185.

    - Tomb,J.-F., White,O., Kerlavage,A.R., Clayton,R.A., Sutton,G.G., Fleischmann,R.D., Ketchum,K.A., Klenk,H.P., Gill,S., Dougherty,B.A., Nelson,K., Quackenbush,J., Zhou,L., Kirkness,E.F., Peterson,S., Loftus,B., Richardson,D., Dodson,R., Khalak,H.G., Glodek,, "Direct Submission", Submitted (18-SEP-2001) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA.

    - Tomb,J.-F., White,O., Kerlavage,A.R., Clayton,R.A., Sutton,G.G., Fleischmann,R.D., Ketchum,K.A., Klenk,H.P., Gill,S., Dougherty,B.A., Nelson,K., Quackenbush,J., Zhou,L., Kirkness,E.F., Peterson,S., Loftus,B., Richardson,D., Dodson,R., Khalak,H.G., Glodek,, "Direct Submission", Submitted (06-AUG-1997) The Institute for Genomic Research, 9712 Medical Center Dr, Rockville, MD 20850, USA.


      






• PAI-like regions homologous to this PAI (genomes and locations)

NC_017374 (Helicobacter pylori 2017): 0.5 Mb
NC_017381 (Helicobacter pylori 2018): 0.5 Mb
NC_000915 (Helicobacter pylori 26695): 0.5 Mb
NC_018939 (Helicobacter pylori 26695): 0.5 Mb
NC_017360 (Helicobacter pylori 35A): 1.0 Mb
NC_017382 (Helicobacter pylori 51): 0.8 Mb
NC_017354 (Helicobacter pylori 52): 0.8 Mb
NC_017375 (Helicobacter pylori 83): 0.9 Mb
NC_017357 (Helicobacter pylori 908): 0.5 Mb
NC_014256 (Helicobacter pylori B8): 0.7 Mb
NC_017358 (Helicobacter pylori Cuz20): 0.6 Mb
NC_017063 (Helicobacter pylori ELS37): 0.8 Mb
NC_017368 (Helicobacter pylori F16): 0.8 Mb
NC_017365 (Helicobacter pylori F30): 0.8 Mb
NC_017366 (Helicobacter pylori F32): 0.5 Mb
NC_017367 (Helicobacter pylori F57): 0.6 Mb
NC_011333 (Helicobacter pylori G27): 0.5 Mb
NC_017371 (Helicobacter pylori Gambia94/24): 0.5 Mb
NC_008086 (Helicobacter pylori HPAG1): 0.5 Mb
NC_017733 (Helicobacter pylori HUP-B14): 0.8 Mb
NC_017372 (Helicobacter pylori India7): 0.8 Mb
NC_000921 (Helicobacter pylori J99): 0.5 Mb
NC_017362 (Helicobacter pylori Lithuania75): 0.5 Mb
NC_020508 (Helicobacter pylori OK113): 0.6 Mb
NC_020509 (Helicobacter pylori OK310): 0.8 Mb
NC_011498 (Helicobacter pylori P12): 0.5 Mb
NC_017742 (Helicobacter pylori PeCan18): 0.5 Mb
NC_014555 (Helicobacter pylori PeCan4): 0.5 Mb
NC_017378 (Helicobacter pylori Puno120): 0.5 Mb
NC_017379 (Helicobacter pylori Puno135): 0.5 Mb
NC_018937 (Helicobacter pylori Rif1): 0.5 Mb
NC_018938 (Helicobacter pylori Rif2): 0.5 Mb
NC_017376 (Helicobacter pylori Santal49): 0.5 Mb
NC_017359 (Helicobacter pylori Sat464): 0.8 Mb
NC_017741 (Helicobacter pylori Shi112): 0.9 Mb
NC_017740 (Helicobacter pylori Shi169): 0.5 Mb
NC_017739 (Helicobacter pylori Shi417): 0.5 Mb
NC_010698 (Helicobacter pylori Shi470): 0.8 Mb
NC_014560 (Helicobacter pylori SJM180): 0.5 Mb
NC_021215 (Helicobacter pylori UM032): 0.9 Mb
NC_021217 (Helicobacter pylori UM037): 0.8 Mb
NC_021218 (Helicobacter pylori UM066): 1.0 Mb
NC_021882 (Helicobacter pylori UM298): 1.5 Mb
NC_021216 (Helicobacter pylori UM299): 0.4 Mb
NC_017355 (Helicobacter pylori v225d): 0.5, 0.5 Mb
NC_017926 (Helicobacter pylori XZ274): 0.9 Mb