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Homologs of nisK gene of NC_017905_P2

protein-level

Hit (GenBank Accn)

Product

Source Genome

Eval.

Ident.(%)

1) nisK
( YP_006309899.1 )

NisK

NC_017905
(Streptococcus parasanguinis FW213)

3e-133

100

2) nisK
( YP_006069692.1 )

two-component sensor histidine kinase

NC_017595
(Streptococcus salivarius JIM8777)

2e-115

3) HMPREF0833_10630
( YP_004621589.1 )

NisK protein

NC_015678
(Streptococcus parasanguinis ATCC 15912)

2e-61

4) SSUBM407_1000
( YP_003028742.1 )

sensor histidine kinase

NC_012926
(Streptococcus suis BM407)

4e-56

5) SSU98_0911
( YP_001200469.1 )

NisK

NC_009443
(Streptococcus suis 98HAH33)

2e-55

6) SSUSC84_0810
( YP_003024824.1 )

sensor histidine kinase

NC_012924
(Streptococcus suis SC84)

2e-55

7) SP70585_1289
( YP_002740531.1 )

NisK

NC_012468
(Streptococcus pneumoniae 70585)

1e-52

• Sequence Alignments

1) nisK in NC_017905


> NC_017905_P2|8|G8|387879596|YP_006309899.1|Streptococcus_parasanguinis_FW213|+|7197..8273|nisK|Spaf_1097|NisK
Length=358

 Score =  468 bits (1763),  Expect = 3e-133, Method: Compositional matrix adjust.
 Identities = 358/358 (100%), Positives = 358/358 (100%), Gaps = 0/358 (0%)

Query  1    MDNALTFNQLIKQTYFKILRQflislflfyllpllftafTNITEKNAGAFTIYFSTISWI  60
            MDNALTFNQLIKQTYFKILRQFLISLFLFYLLPLLFTAFTNITEKNAGAFTIYFSTISWI
Sbjct  1    MDNALTFNQLIKQTYFKILRQFLISLFLFYLLPLLFTAFTNITEKNAGAFTIYFSTISWI  60

Query  61   YISLILFSIIAKNISNLLEKIKQETNIVYNQSLLVDINEQAPAKLTLIELIETRQKIQEM  120
            YISLILFSIIAKNISNLLEKIKQETNIVYNQSLLVDINEQAPAKLTLIELIETRQKIQEM
Sbjct  61   YISLILFSIIAKNISNLLEKIKQETNIVYNQSLLVDINEQAPAKLTLIELIETRQKIQEM  120

Query  121  QSTIKKMIQSEKQQKKELMFQVSAAAHDLKTPLTIIQGNAQFLQSIDITGNIGQCLGDIE  180
            QSTIKKMIQSEKQQKKELMFQVSAAAHDLKTPLTIIQGNAQFLQSIDITGNIGQCLGDIE
Sbjct  121  QSTIKKMIQSEKQQKKELMFQVSAAAHDLKTPLTIIQGNAQFLQSIDITGNIGQCLGDIE  180

Query  181  IASQQLNRYFNQLINYSKTFYNDSSNWESFSSDYLLELFEQEIKLITDKKAKIQFSnnlp  240
            IASQQLNRYFNQLINYSKTFYNDSSNWESFSSDYLLELFEQEIKLITDKKAKIQFSNNLP
Sbjct  181  IASQQLNRYFNQLINYSKTFYNDSSNWESFSSDYLLELFEQEIKLITDKKAKIQFSNNLP  240

Query  241  itinltlnlnlflrailniinnaiDHSKSNYPLIRVDYKLIDNKFYISIWNSDSSFSENI  300
            ITINLTLNLNLFLRAILNIINNAIDHSKSNYPLIRVDYKLIDNKFYISIWNSDSSFSENI
Sbjct  241  ITINLTLNLNLFLRAILNIINNAIDHSKSNYPLIRVDYKLIDNKFYISIWNSDSSFSENI  300

Query  301  LEKYGLLYYQDKQATNSEQGSHFGIGLAFVNRVAKIHGGEVNLSNFENGALVTIYIPV  358
            LEKYGLLYYQDKQATNSEQGSHFGIGLAFVNRVAKIHGGEVNLSNFENGALVTIYIPV
Sbjct  301  LEKYGLLYYQDKQATNSEQGSHFGIGLAFVNRVAKIHGGEVNLSNFENGALVTIYIPV  358

2) nisK in NC_017595


> NC_017905_P2|8|G8|387879596|YP_006309899.1|Streptococcus_parasanguinis_FW213|+|7197..8273|nisK|Spaf_1097|NisK
Length=358

 Score =  409 bits (1538),  Expect = 2e-115, Method: Compositional matrix adjust.
 Identities = 303/358 (85%), Positives = 338/358 (95%), Gaps = 0/358 (0%)

Query  1    MEKSLTFNQLVKQTYFKILRQflinlflfyllpmlltafTNITEKNAGAFTIYFSTASWI  60
            M+++LTFNQL+KQTYFKILRQFLI+LFLFYLLP+L+TAFTNITEKNAGAFTIYFST SWI
Sbjct  1    MDNALTFNQLIKQTYFKILRQFLISLFLFYLLPLLFTAFTNITEKNAGAFTIYFSTISWI  60

Query  61   YISLILLFSITKNMRNLLEKIKQETIIVYNQSLLGDTNENNSAKLTLIELIETRQKIQEM  120
            YISLIL+  I+KN+ NLLEKIKQET IVYNQSLL D NE+ +AKLTLIELIETRQKIQEM
Sbjct  61   YISLILFSIIAKNISNLLEKIKQETNIVYNQSLLVDINEQAPAKLTLIELIETRQKIQEM  120

Query  121  QATikkiiqsekqqkqeLMFQVSAAAHDLKTPLTVIQGNAQFLQSMDIPGNIEQCLEDIE  180
            Q+TIKK+IQSEKQQK+ELMFQVSAAAHDLKTPLT+IQGNAQFLQS+DI GNI QCL DIE
Sbjct  121  QSTIKKMIQSEKQQKKELMFQVSAAAHDLKTPLTIIQGNAQFLQSIDITGNIGQCLGDIE  180

Query  181  LASQQLNLYFNQLINYSKTFYNDTSNWESLSSDYLFELFEQEIKLITDKKADIQFSNNLP  240
            +ASQQLN YFNQLINYSKTFYND+SNWES+SSDYL+ELFEQEIKLITDKKA IQFSNNLP
Sbjct  181  IASQQLNRYFNQLINYSKTFYNDSSNWESFSSDYLLELFEQEIKLITDKKAKIQFSNNLP  240

Query  241  TSIYLTLNLNLFLRATLNIINNAIDHSQSSYPTIKVNYKFIDNQFYISIWNSDSSFTENL  300
             +I LTLNLNLFLRA LNIINNAIDHS+S+YP I+V+YK+IDN+FYISIWNSDSSF+EN+
Sbjct  241  ITINLTLNLNLFLRAILNIINNAIDHSKSNYPLIRVDYKLIDNKFYISIWNSDSSFSENI  300

Query  301  LEKYGLLFYQDKQATNSEQRSNFGIGLAFVKRVAKIHGGQVNLSNCNNGALVTICIPV  358
            LEKYGLL+YQDKQATNSEQ S+FGIGLAFV+RVAKIHGG+VNLSN +NGALVTI IPV
Sbjct  301  LEKYGLLYYQDKQATNSEQGSHFGIGLAFVNRVAKIHGGEVNLSNFENGALVTIYIPV  358

3) HMPREF0833_10630 in NC_015678


> NC_017905_P2|8|G8|387879596|YP_006309899.1|Streptococcus_parasanguinis_FW213|+|7197..8273|nisK|Spaf_1097|NisK
Length=358

 Score =  229 bits (855),  Expect = 2e-61, Method: Compositional matrix adjust.
 Identities = 169/358 (48%), Positives = 269/358 (76%), Gaps = 2/358 (0%)

Query  1    MEKELTIKQLIKRTYLKIIWQFLLCLILFYIVPALLSSVSGINEKNANHFALFFSVSSWi  60
            M++ LT++QLIK+TY+KI++QFL+ L+LFY++P L+++ + I EKNA  F+++FS  SWI
Sbjct  1    MDNALTFNQLIKQTYFKILRQFLISLFLFYLLPLLFTAFTNITEKNAGAFTIYFSTISWI  60

Query  61   ylciilifiivinirqllTKIQKEMNMVYHSGLYFTKNEHHH--LQIKEFIETNDLIEKM  118
            Y+ +IL+ II  NI +LL KI++E N+VY+ +L    NE+    L + E+IET + I+ M
Sbjct  61   YISLILFSIIAKNISNLLEKIKQETNIVYNQSLLVDINEQAPAKLTLIELIETRQKIQEM  120

Query  119  QSEIKNRIQNEKDQKKELMFQVSSAAHDLRSPLTVIRGNAEFLQSTEQTPQTMECLKDLE  178
            QS IK+ IQ+EK+QKKELMFQVS+AAHDL++PLT+I+GNA+FLQS + T +  +CL D+E
Sbjct  121  QSTIKKMIQSEKQQKKELMFQVSAAAHDLKTPLTIIQGNAQFLQSIDITGNIGQCLGDIE  180

Query  179  QASIQLNDYFNHFIQYSKTFYDHDIQLENISIQQVTHQLKEQITPLLPRNTQFVFSNTVT  238
             AS QLN YFN++I+YSKTFY++  + E++S + + + + ++I  +  +++++ FSN + 
Sbjct  181  IASQQLNRYFNQLINYSKTFYNDSSNWESFSSDYLLELFEQEIKLITDKKAKIQFSNNLP  240

Query  239  PSTQIAIHSNLFFRAITNIINNAIQHQKDNDAKIQLTMSQEKNRLVLTIWNNQSTFSKNV  298
             + +++++ NLF+RAI NIINNAI+H K N + I++      N++ ++IWN++S+FS N+
Sbjct  241  ITINLTLNLNLFLRAILNIINNAIDHSKSNYPLIRVDYKLIDNKFYISIWNSDSSFSENI  300

Query  299  LQHAGNLFYKEDQARTPSQESHFGLGLSFVKRVMKLHNGTMHLENTHNGAQVKLIIPI  356
            L+  G L+Y++ QA  + Q SHFG+GL+FV+RV K+H G ++L N +NGA V + IP+
Sbjct  301  LEKYGLLYYQDKQATNSEQGSHFGIGLAFVNRVAKIHGGEVNLSNFENGALVTIYIPV  358

4) SSUBM407_1000 in NC_012926


> NC_017905_P2|8|G8|387879596|YP_006309899.1|Streptococcus_parasanguinis_FW213|+|7197..8273|nisK|Spaf_1097|NisK
Length=358

 Score =  211 bits (786),  Expect = 4e-56, Method: Compositional matrix adjust.
 Identities = 151/362 (42%), Positives = 255/362 (71%), Gaps = 7/362 (1%)

Query  1    MERKLDFKTLVKKTQWTIIKQFCLSVIVAYIFPISTISIDIHSETQSIASDLLGIFFNVF  60
            M+  L F+ L+K+T   I++QF +S+++ Y++P+   ++   +E ++ A   + I+F+ +
Sbjct  1    MDNALTFNQLIKQTYFKILRQFLISLFLFYLLPLLFTAFTNITEKNAGA---FTIYFSTI  57

Query  61   SWVYICISLIIIVSVNIKALLKRVKQEMEIVYHGSMWLTSVN--TSSKLTILEFIETNKH  118
            SW+YI + L+ I++ NI  LL ++KQE +IVY+ S+ L  +N  +++KLT++E+IET + 
Sbjct  58   SWIYISLILFSIIAKNISNLLEKIKQETNIVYNQSL-LVDINEQAPAKLTLIELIETRQK  116

Query  119  IELMQQRIKNMIQVEKDQKEDILFKVSAMAHDLKTPLTVIKGNSELLQFAPLSGIDVQCL  178
            I+ MQ  IK+MIQ EK+QK +++F+VSA AHDLKTPLT+I+GN+++LQ   ++G   QCL
Sbjct  117  IQEMQSTIKKMIQSEKQQKKELMFQVSAAAHDLKTPLTIIQGNAQFLQSIDITGNIGQCL  176

Query  179  RDIERASNQLDNYFNQLINYSKTFYSNQISFHQYSISNLSKILEQECAYLIGDSIDYKYE  238
             DIE AS+QL+ YFNQLINYSKTFY++  + + +S   L  ++EQE   + +     ++ 
Sbjct  177  GDIEIASQQLNRYFNQLINYSKTFYNDSSNWESFSSDYLLELFEQEIKLITDKKAKIQFS  236

Query  239  TKIGRDCNIELDLDLIIRSVSNIVNNAIAYADDVKKKIRVileledssislsiWNNGSKF  298
             ++    N+ L+L+L++R++ NI+NNAI  +      IRV   L D+ + +SIWN++S F
Sbjct  237  NNLPITINLTLNLNLFLRAILNIINNAIDHSKSNYPLIRVDYKLIDNKFYISIWNSDSSF  296

Query  299  SDDVLENFGKLFYRE-DTSRNSQFEHFGIGLAFVKQVMSIHSGDIQLQNKKNGAMVKLII  357
            S+++LE++G L+Y++ +++ + Q  HFGIGLAFV++V  IH+G+++L N  NGA+V + I
Sbjct  297  SENILEKYGLLYYQDKQATNSEQGSHFGIGLAFVNRVAKIHGGEVNLSNFENGALVTIYI  356

Query  358  PI  359
            P+
Sbjct  357  PV  358

5) SSU98_0911 in NC_009443


> NC_017905_P2|8|G8|387879596|YP_006309899.1|Streptococcus_parasanguinis_FW213|+|7197..8273|nisK|Spaf_1097|NisK
Length=358

 Score =  209 bits (778),  Expect = 2e-55, Method: Compositional matrix adjust.
 Identities = 148/361 (41%), Positives = 256/361 (71%), Gaps = 5/361 (1%)

Query  1    MERKLDFKTLVKKTQWTIIKQFCLSVIVAYIFPISTISIDIHSETQLIASDLLGIFFNVF  60
            M+  L F+ L+K+T   I++QF +S+++ Y++P+   ++   +E +   ++ + I+F+ +
Sbjct  1    MDNALTFNQLIKQTYFKILRQFLISLFLFYLLPLLFTAFTNITEKN---AGAFTIYFSTI  57

Query  61   SWVYICISLIIIVSVNIKALLKRVKQEMEIVYHGSMWLT-SVNTSSKLTILEFIETNKHI  119
            SW+YI + L+ I++ NI  LL ++KQE +IVY+ S+ +  + ++++KLT++E+IET + I
Sbjct  58   SWIYISLILFSIIAKNISNLLEKIKQETNIVYNQSLLVDINEQAPAKLTLIELIETRQKI  117

Query  120  ELMQQRIKNMIQVEKDQKEDILFKVSAMAHDLKTPLTVIKGNSELLQFAPLSGIDVQCLR  179
            + MQ  IK+MIQ EK+QK +++F+VSA AHDLKTPLT+I+GN+++LQ   ++G   QCL 
Sbjct  118  QEMQSTIKKMIQSEKQQKKELMFQVSAAAHDLKTPLTIIQGNAQFLQSIDITGNIGQCLG  177

Query  180  DIERASNQLDNYFNQLINYSKTFYSNQISFHQYSISNLSKILEQECAYLIGDNIDYKYET  239
            DIE AS+QL+ YFNQLINYSKTFY++  + + +S   L  ++EQE   + + +   ++  
Sbjct  178  DIEIASQQLNRYFNQLINYSKTFYNDSSNWESFSSDYLLELFEQEIKLITDKKAKIQFSN  237

Query  240  KIWRDCNIELDLDLIIRSVSNIVNNAIAYADDVKKKIRVileledssislsiWNNGSKFS  299
            ++    N+ L+L+L++R++ NI+NNAI  +      IRV   L D+ + +SIWN++S FS
Sbjct  238  NLPITINLTLNLNLFLRAILNIINNAIDHSKSNYPLIRVDYKLIDNKFYISIWNSDSSFS  297

Query  300  DDVLENFGKLFYRE-DTSRNSQFEHFGIGLAFVKQVMSIHSGDIQLQNKKNGAMVKLIIP  358
            +++LE++G L+Y++ +++ + Q  HFGIGLAFV++V  IH+G+++L N  NGA+V + IP
Sbjct  298  ENILEKYGLLYYQDKQATNSEQGSHFGIGLAFVNRVAKIHGGEVNLSNFENGALVTIYIP  357

Query  359  I  359
            +
Sbjct  358  V  358

6) SSUSC84_0810 in NC_012924


> NC_017905_P2|8|G8|387879596|YP_006309899.1|Streptococcus_parasanguinis_FW213|+|7197..8273|nisK|Spaf_1097|NisK
Length=358

 Score =  209 bits (778),  Expect = 2e-55, Method: Compositional matrix adjust.
 Identities = 148/361 (41%), Positives = 256/361 (71%), Gaps = 5/361 (1%)

Query  1    MERKLDFKTLVKKTQWTIIKQFCLSVIVAYIFPISTISIDIHSETQLIASDLLGIFFNVF  60
            M+  L F+ L+K+T   I++QF +S+++ Y++P+   ++   +E +   ++ + I+F+ +
Sbjct  1    MDNALTFNQLIKQTYFKILRQFLISLFLFYLLPLLFTAFTNITEKN---AGAFTIYFSTI  57

Query  61   SWVYICISLIIIVSVNIKALLKRVKQEMEIVYHGSMWLT-SVNTSSKLTILEFIETNKHI  119
            SW+YI + L+ I++ NI  LL ++KQE +IVY+ S+ +  + ++++KLT++E+IET + I
Sbjct  58   SWIYISLILFSIIAKNISNLLEKIKQETNIVYNQSLLVDINEQAPAKLTLIELIETRQKI  117

Query  120  ELMQQRIKNMIQVEKDQKEDILFKVSAMAHDLKTPLTVIKGNSELLQFAPLSGIDVQCLR  179
            + MQ  IK+MIQ EK+QK +++F+VSA AHDLKTPLT+I+GN+++LQ   ++G   QCL 
Sbjct  118  QEMQSTIKKMIQSEKQQKKELMFQVSAAAHDLKTPLTIIQGNAQFLQSIDITGNIGQCLG  177

Query  180  DIERASNQLDNYFNQLINYSKTFYSNQISFHQYSISNLSKILEQECAYLIGDNIDYKYET  239
            DIE AS+QL+ YFNQLINYSKTFY++  + + +S   L  ++EQE   + + +   ++  
Sbjct  178  DIEIASQQLNRYFNQLINYSKTFYNDSSNWESFSSDYLLELFEQEIKLITDKKAKIQFSN  237

Query  240  KIWRDCNIELDLDLIIRSVSNIVNNAIAYADDVKKKIRVileledssislsiWNNGSKFS  299
            ++    N+ L+L+L++R++ NI+NNAI  +      IRV   L D+ + +SIWN++S FS
Sbjct  238  NLPITINLTLNLNLFLRAILNIINNAIDHSKSNYPLIRVDYKLIDNKFYISIWNSDSSFS  297

Query  300  DDVLENFGKLFYRE-DTSRNSQFEHFGIGLAFVKQVMSIHSGDIQLQNKKNGAMVKLIIP  358
            +++LE++G L+Y++ +++ + Q  HFGIGLAFV++V  IH+G+++L N  NGA+V + IP
Sbjct  298  ENILEKYGLLYYQDKQATNSEQGSHFGIGLAFVNRVAKIHGGEVNLSNFENGALVTIYIP  357

Query  359  I  359
            +
Sbjct  358  V  358

7) SP70585_1289 in NC_012468


> NC_017905_P2|8|G8|387879596|YP_006309899.1|Streptococcus_parasanguinis_FW213|+|7197..8273|nisK|Spaf_1097|NisK
Length=358

 Score =  200 bits (742),  Expect = 1e-52, Method: Compositional matrix adjust.
 Identities = 151/362 (42%), Positives = 257/362 (71%), Gaps = 7/362 (1%)

Query  1    MERKLDFKTLVKKTKWTIVKQFCLNIIVAYIFPISTISIDIHSETQSIARDLLGVLFNVF  60
            M+  L F+ L+K+T   I++QF +++++ Y++P+   ++   +E ++ A   + + F+ +
Sbjct  1    MDNALTFNQLIKQTYFKILRQFLISLFLFYLLPLLFTAFTNITEKNAGA---FTIYFSTI  57

Query  61   SWVYicisliiivsiniKALLTRVKQEMEIVYHSSIWLTSVND--SSNLTILEFIETNRH  118
            SW+YI + L+ I++ NI  LL ++KQE +IVY+ S+ L  +N+  +++LT++E+IET + 
Sbjct  58   SWIYISLILFSIIAKNISNLLEKIKQETNIVYNQSL-LVDINEQAPAKLTLIELIETRQK  116

Query  119  IESMQQRIKNMIQVEKDQKADILFKVSAMAHDLKTPLTVIKGNSELLQLAPLSGIDVQCL  178
            I+ MQ  IK+MIQ EK+QK +++F+VSA AHDLKTPLT+I+GN+++LQ   ++G   QCL
Sbjct  117  IQEMQSTIKKMIQSEKQQKKELMFQVSAAAHDLKTPLTIIQGNAQFLQSIDITGNIGQCL  176

Query  179  KDIERASNQLNSYFNQLINYSKTFYSDQISFHQYRISNLSKILEQECTYLIGDSIDYKYS  238
             DIE AS+QLN YFNQLINYSKTFY+D  + + +    L  ++EQE   + +     ++S
Sbjct  177  GDIEIASQQLNRYFNQLINYSKTFYNDSSNWESFSSDYLLELFEQEIKLITDKKAKIQFS  236

Query  239  TKIDRDCNIELDLDLIIRSvanivnnaiayaddakkkiRVTFELADSNITLSIWNNGSKF  298
             ++    N+ L+L+L++R++ NI+NNAI  +      IRV + L D+++ +SIWN++S F
Sbjct  237  NNLPITINLTLNLNLFLRAILNIINNAIDHSKSNYPLIRVDYKLIDNKFYISIWNSDSSF  296

Query  299  SDDVLENFGKLFYRE-DTSRNSQFEHFGIGLAFVKQVMSIHSGDIQLQNKENGAMVKLII  357
            S+++LE++G L+Y++ +++ + Q  HFGIGLAFV++V  IH+G+++L N ENGA+V + I
Sbjct  297  SENILEKYGLLYYQDKQATNSEQGSHFGIGLAFVNRVAKIHGGEVNLSNFENGALVTIYI  356

Query  358  PM  359
            P+
Sbjct  357  PV  358