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Homologs of EFAU085_00689 gene of NC_021994_R1

protein-level

Hit (GenBank Accn)

Product

Source Genome

Eval.

Ident.(%)

1) EFAU085_00689
( YP_008394213.1 )

HNH endonuclease domain protein

NC_021994
(Enterococcus faecium AUS0085)

0.0

100

2) CLS_04950
( YP_007848311.1 )

Retron-type reverse transcriptase

NC_021047
(Clostridium saccharolyticum K10)

6e-149

3) Dhaf_1533
( YP_002458021.1 )

RNA-directed DNA polymerase

NC_011830
(Desulfitobacterium hafniense DCB-2)

4e-143

4) LL3_02382
( YP_005546144.1 )

Group II intron-encoded protein LtrA

NC_017190
(Bacillus amyloliquefaciens LL3)

5e-138

5) DSY4554
( YP_520787.1 )

hypothetical protein

NC_007907
(Desulfitobacterium hafniense Y51)

5e-130

6) MC28_E169
( YP_006815667.1 )

Group II intron-encoded protein LtrA

NC_018687
(Bacillus thuringiensis MC28)

3e-127

7) DSY0050
( YP_516283.1 )

hypothetical protein

NC_007907
(Desulfitobacterium hafniense Y51)

3e-126

8) DSY4652
( YP_520885.1 )

hypothetical protein

NC_007907
(Desulfitobacterium hafniense Y51)

3e-126

9) Odosp_0220
( YP_004251505.1 )

RNA-directed DNA polymerase (Reverse transcriptase)

NC_015160
(Odoribacter splanchnicus DSM 220712)

1e-123

10) Odosp_1207
( YP_004252441.1 )

RNA-directed DNA polymerase (Reverse transcriptase)

NC_015160
(Odoribacter splanchnicus DSM 220712)

1e-123

11) Alfi_3211
( YP_006412126.1 )

Retron-type reverse transcriptase

NC_018011
(Alistipes finegoldii DSM 17242)

6e-123

12) BF638R_1362
( YP_005110448.1 )

putative maturase/reverse transcriptase

NC_016776
(Bacteroides fragilis 638R)

6e-122

13) BF638R_2096
( YP_005111156.1 )

putative maturase reverse transcriptase

NC_016776
(Bacteroides fragilis 638R)

6e-122

14) BT_2602
( NP_811515.1 )

maturase/reverse transcriptase

NC_004663
(Bacteroides thetaiotaomicron VPI-5482)

6e-122

15) OBV_44960
( YP_004884200.1 )

group II intron-encoded protein

NC_016048
(Oscillibacter valericigenes Sjm18-20)

8e-122

16) Alfi_2157
( YP_006411131.1 )

Retron-type reverse transcriptase

NC_018011
(Alistipes finegoldii DSM 17242)

2e-121

17) AL1_29310
( YP_007817804.1 )

Retron-type reverse transcriptase

NC_021030
(Alistipes shahii WAL 8301)

3e-121

18) Alfi_0692
( YP_006409756.1 )

Retron-type reverse transcriptase

NC_018011
(Alistipes finegoldii DSM 17242)

4e-119

19) Alfi_2107
( YP_006411086.1 )

Retron-type reverse transcriptase

NC_018011
(Alistipes finegoldii DSM 17242)

4e-119

20) SPN23F_12790
( YP_002511214.1 )

group II intron reverse transcriptase/maturase

NC_011900
(Streptococcus pneumoniae ATCC 700669)

4e-119

21) BCQ_2135
( YP_002529852.1 )

reverse transcriptase

NC_011969
(Bacillus cereus Q1)

5e-119

22) Alfi_0686
( YP_006409753.1 )

Retron-type reverse transcriptase

NC_018011
(Alistipes finegoldii DSM 17242)

2e-118

23) Alfi_0997
( YP_006410042.1 )

Retron-type reverse transcriptase

NC_018011
(Alistipes finegoldii DSM 17242)

2e-118

24) MGAS10750_Spy1709
( YP_603203.1 )

Reverse transcriptase / RNA maturase / endonuclease

NC_008024
(Streptococcus pyogenes MGAS10750)

9e-117

25) HD73_2733
( YP_007421832.1 )

Reverse transcriptase / RNA maturase / Endonuclease

NC_020238
(Bacillus cereus HD73)

3e-116

26) Clocel_2353
( YP_003843833.1 )

RNA-directed DNA polymerase

NC_014393
(Clostridium cellulovorans 743B)

7e-116

27) CT43_P281092
( YP_005569539.1 )

Reverse transcriptase / RNA maturase / Endonuclease

NC_017203
(Bacillus thuringiensis CT-43)

8e-115

28) H175_285p099
( YP_007482479.1 )

Retron-type RNA-directed DNA polymerase

NC_020384
(Bacillus thuringiensis IS5056)

8e-115

29) Smon_0664
( YP_003306015.1 )

RNA-directed DNA polymerase

NC_013515
(Streptobacillus moniliformis DSM 12112)

4e-112

30) BCQ_PI011
( YP_002533188.1 )

putative maturase/reverse transcriptase

NC_011973
(Bacillus cereus Q1)

3e-110

31) BCG9842_B4556
( YP_002444188.1 )

group II intron-encoded protein LtrA

NC_011772
(Bacillus cereus G9842)

1e-109

32) BCG9842_B1762
( YP_002446949.1 )

group II intron-encoded protein LtrA

NC_011772
(Bacillus cereus G9842)

1e-109

33) BCG9842_B5597
( YP_002448770.1 )

group II intron-encoded protein LtrA

NC_011772
(Bacillus cereus G9842)

1e-109

34) AL1_03430
( YP_007815782.1 )

Retron-type reverse transcriptase

NC_021030
(Alistipes shahii WAL 8301)

4e-107

35) matR
( YP_001032672.1 )

maturase

NC_009004
(Lactococcus lactis MG1363)

1e-98

36) LLNZ_07090
( YP_006356788.1 )

maturase

NC_017949
(Lactococcus lactis NZ9000)

1e-98

37) LACR_C19
( YP_796487.1 )

maturase MatR

NC_008505
(Lactococcus lactis SK11)

3e-98

38) llh_13615
( YP_005877308.1 )

Retron-type reverse transcriptase

NC_017496
(Lactococcus lactis A76)

4e-98

39) LACR_1685
( YP_809603.1 )

retron-type reverse transcriptase

NC_008527
(Lactococcus lactis SK11)

4e-98

40) AL1_27550
( YP_007817661.1 )

Retron-type reverse transcriptase

NC_021030
(Alistipes shahii WAL 8301)

8e-98

41) SeseC_01322
( YP_006042981.1 )

maturase

NC_017582
(Streptococcus equi ATCC 35246)

2e-96

42) Bcer98_3169
( YP_001376387.1 )

RNA-directed DNA polymerase

NC_009674
(Bacillus cytotoxicus NVH 391-98)

2e-75

• Sequence Alignments

1) EFAU085_00689 in NC_021994


> NC_021994_R1|7|G7|529233401|YP_008394213.1|Enterococcus_faecium_Aus0085|+|4653..6470|-|EFAU085_00689|HNH 
endonuclease domain 
protein
Length=605

 Score =  933 bits (3535),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 605/605 (100%), Positives = 605/605 (100%), Gaps = 0/605 (0%)

Query  1    MRNPIHVLKSLEEKASVSNYKYERLYRNLYNPEFYLLAYANIAKSQGSMTQGVDGQTLDN  60
            MRNPIHVLKSLEEKASVSNYKYERLYRNLYNPEFYLLAYANIAKSQGSMTQGVDGQTLDN
Sbjct  1    MRNPIHVLKSLEEKASVSNYKYERLYRNLYNPEFYLLAYANIAKSQGSMTQGVDGQTLDN  60

Query  61   MSLPrinriiesirnrTYQPKPAKRKYIPKKNGKLRPLGITSTDDKLVQEVVRMILEAIY  120
            MSLPRINRIIESIRNRTYQPKPAKRKYIPKKNGKLRPLGITSTDDKLVQEVVRMILEAIY
Sbjct  61   MSLPRINRIIESIRNRTYQPKPAKRKYIPKKNGKLRPLGITSTDDKLVQEVVRMILEAIY  120

Query  121  EPTFSNNSHGFRPKRSCHTALTQVKKNFTGVTWIVEGDIKACFDNFDHHVLVELLRKRIS  180
            EPTFSNNSHGFRPKRSCHTALTQVKKNFTGVTWIVEGDIKACFDNFDHHVLVELLRKRIS
Sbjct  121  EPTFSNNSHGFRPKRSCHTALTQVKKNFTGVTWIVEGDIKACFDNFDHHVLVELLRKRIS  180

Query  181  DEAFIGLIWKFLKAGYMEQWQYNCTYSGVPQGSGISPICANIYLSELDNYMQEYKEKYDC  240
            DEAFIGLIWKFLKAGYMEQWQYNCTYSGVPQGSGISPICANIYLSELDNYMQEYKEKYDC
Sbjct  181  DEAFIGLIWKFLKAGYMEQWQYNCTYSGVPQGSGISPICANIYLSELDNYMQEYKEKYDC  240

Query  241  EPErrrttreyerasrryrkarkALMGAEKSTPELVKEFKDSRRKKMNQHYYNPFEEGFK  300
            EPERRRTTREYERASRRYRKARKALMGAEKSTPELVKEFKDSRRKKMNQHYYNPFEEGFK
Sbjct  241  EPERRRTTREYERASRRYRKARKALMGAEKSTPELVKEFKDSRRKKMNQHYYNPFEEGFK  300

Query  301  KIQYNRYADDFVIGVIGSKKDAEKIKEDVKIFLQEKLHLEMSEEKTKVTHSSKPVRYLGY  360
            KIQYNRYADDFVIGVIGSKKDAEKIKEDVKIFLQEKLHLEMSEEKTKVTHSSKPVRYLGY
Sbjct  301  KIQYNRYADDFVIGVIGSKKDAEKIKEDVKIFLQEKLHLEMSEEKTKVTHSSKPVRYLGY  360

Query  361  DFKVIHSKNMKRCKNGDMKRVWYGKVFLYMPKEKWIKKAMERGAIQVKRNNDTGKEMWRP  420
            DFKVIHSKNMKRCKNGDMKRVWYGKVFLYMPKEKWIKKAMERGAIQVKRNNDTGKEMWRP
Sbjct  361  DFKVIHSKNMKRCKNGDMKRVWYGKVFLYMPKEKWIKKAMERGAIQVKRNNDTGKEMWRP  420

Query  421  MPRKDLMNRSDAEIVSTFNSEIRGLYNFYRIAENVGALHKYYYMVRYSMLKTLAGKHRTN  480
            MPRKDLMNRSDAEIVSTFNSEIRGLYNFYRIAENVGALHKYYYMVRYSMLKTLAGKHRTN
Sbjct  421  MPRKDLMNRSDAEIVSTFNSEIRGLYNFYRIAENVGALHKYYYMVRYSMLKTLAGKHRTN  480

Query  481  VSVIKKRHMVNGVLRIPYDTTKGRKYCEFYHDGFRKHSDGYDNVADVMPSYRKYDSRHTI  540
            VSVIKKRHMVNGVLRIPYDTTKGRKYCEFYHDGFRKHSDGYDNVADVMPSYRKYDSRHTI
Sbjct  481  VSVIKKRHMVNGVLRIPYDTTKGRKYCEFYHDGFRKHSDGYDNVADVMPSYRKYDSRHTI  540

Query  541  VNRIKAGVCEICGEHADYLCMHHVRTLKSLKGRDIFEQKMLKMRRKSLALCPDCFELLHE  600
            VNRIKAGVCEICGEHADYLCMHHVRTLKSLKGRDIFEQKMLKMRRKSLALCPDCFELLHE
Sbjct  541  VNRIKAGVCEICGEHADYLCMHHVRTLKSLKGRDIFEQKMLKMRRKSLALCPDCFELLHE  600

Query  601  TKESR  605
            TKESR
Sbjct  601  TKESR  605

2) CLS_04950 in NC_021047


> NC_021994_R1|7|G7|529233401|YP_008394213.1|Enterococcus_faecium_Aus0085|+|4653..6470|-|EFAU085_00689|HNH 
endonuclease domain 
protein
Length=605

 Score =  521 bits (1965),  Expect = 6e-149, Method: Compositional matrix adjust.
 Identities = 304/609 (50%), Positives = 439/609 (73%), Gaps = 8/609 (1%)

Query  1    MRSPENVLESLKSKACNQSYKYERLYRNLYNPQFYLLAYQRIQAKPGNMTAGTDGKTIDG  60
            MR+P +VL SL  KA   +YKYERLYRNLYNP+FYLLAY  I    G+MT G DG+T+D 
Sbjct  1    MRNPIHVLKSLEEKASVSNYKYERLYRNLYNPEFYLLAYANIAKSQGSMTQGVDGQTLDN  60

Query  61   MGMARINALIEKMRNSSYQPNPARRTYIPKSNGKMRPLGIPSFDDKLIQEVVRLILESIY  120
            M+++RIN +IE +RN +YQP+PA+R YIPK NGK+RPLGI S DDKL+QEVVR+ILE+IY
Sbjct  61   MSLPRINRIIESIRNRTYQPKPAKRKYIPKKNGKLRPLGITSTDDKLVQEVVRMILEAIY  120

Query  121  EPTFSDHSHGFRMNKSCHTALKYVQKYFTGTKWFVEGDIKGCFDNVDHHVLIAILRKRIA  180
            EPTFS++SHGFR ++SCHTAL  V+K FTG  W+VEGDIK+CFDN DHHVL+ +LRKRI+
Sbjct  121  EPTFSNNSHGFRPKRSCHTALTQVKKNFTGVTWIVEGDIKACFDNFDHHVLVELLRKRIS  180

Query  181  DEQFIGLLWKFLKAGYMEDWNYHNTYSGTPQGSIISPILANIYLNELDHFMAEYAEKFNC  240
            DE FIGL+WKFLKAGYME+W+Y+ TYSG PQGS ISPI ANIYL+ELD++M EY EK++C
Sbjct  181  DEAFIGLIWKFLKAGYMEQWQYNCTYSGVPQGSGISPICANIYLSELDNYMQEYKEKYDC  240

Query  241  GDRRRINPAFKKKLDVCRGKEERLKRNISKMSEEEKEGLLAEISELRRSLRSMPYSDQMD  300
               RR       +     ++  R  R+    +E     L+ E+ + RR   +  Y +  +
Sbjct  241  EPERRRTTREYERA----SRRYRKARKALMGAEKSTPELVKEFKDSRRKKMNQHYYNPFE  296

Query  301  EGYKRVFYIRYADDFLIGVIGRKADAEQVKQDVGHFIRENLHLEMSEEKTLITHGHDFAK  360
            EG+K++ Y RYADDF+IGVIG K DAE++K+DV  F++E+LHLEMSEEKT +TH+    +
Sbjct  297  EGFKKIQYNRYADDFVIGVIGSKKDAEKIKEDVKIFLQEKLHLEMSEEKTKVTHSSKPVR  356

Query  361  FLGYEVTIAKGECNKKTRTGATRRVNNGKVLLYVPHDKWIKRLLSYHALKIRYDKQNGNR  420
            +LGY+  +  +   K+ + G  +RV  GKV+LY+P +KWIK+ +   A++++ +++ G +
Sbjct  357  YLGYDFKVIHSKNMKRCKNGDMKRVWYGKVFLYMPKEKWIKKAMERGAIQVKRNNDTG-K  415

Query  421  EVWEPVRRTRLLHLDDLEILNQYNAEIRGLYNYYRLANNVSVLNNFYYVMRYSMLKTFSG  480
            E+W P+ R  L++  D EI++ +N+EIRGLYN+YR+A+NV+ L+++YY++RYSMLKT++G
Sbjct  416  EMWRPMPRKDLMNRSDAEIVSTFNSEIRGLYNFYRIAENVGALHKYYYMVRYSMLKTLAG  475

Query  481  KYRTRISRIIQKYRQGKDFVVEYPKKNGQVGKVLFYNNGFRRDTKVESGNPDVIARVFEN  540
            K RT +S I ++      + + Y   +G+     FY++GFR+++      +DV++  + +
Sbjct  476  KHRTNVSVIKKRHMVNGVLRIPYDTTKGR-KYCEFYHDGFRKHSDGYDNVADVMP-SYRK  533

Query  541  Y-GRNSLIKRLKASRCEWCGAENVPIEIHHVRKLKDLSGKKQWEIAMIGRKRKTMALCVD  599
            Y +R+++++R+KA+ CE CG +   + +HHVR LK L G+   E  M+  +RK++ALC D
Sbjct  534  YDSRHTIVNRIKAGVCEICGEHADYLCMHHVRTLKSLKGRDIFEQKMLKMRRKSLALCPD  593

Query  600  CHDKLHAGK  608
            C + LH  K
Sbjct  594  CFELLHETK  602

3) Dhaf_1533 in NC_011830


> NC_021994_R1|7|G7|529233401|YP_008394213.1|Enterococcus_faecium_Aus0085|+|4653..6470|-|EFAU085_00689|HNH 
endonuclease domain 
protein
Length=605

 Score =  501 bits (1891),  Expect = 4e-143, Method: Compositional matrix adjust.
 Identities = 287/609 (48%), Positives = 435/609 (72%), Gaps = 13/609 (2%)

Query  1    MRSPQIVLENLQRQSQKQDYRFERLYRNLYNPDFYLLAYQKLYANNGAMTPGVDRTTLDG  60
            MR+P  VL +L+ ++   +Y++ERLYRNLYNP+FYLLAY ++  ++G+MT GVD  TLD 
Sbjct  1    MRNPIHVLKSLEEKASVSNYKYERLYRNLYNPEFYLLAYANIAKSQGSMTQGVDGQTLDN  60

Query  61   TGMERIESLIQSLKNRSYQPQPARRRYIPKKSGKGQRPLGIQAANDKLVQEVVRMLLESI  120
             ++ RI+ +I+S++NR+YQP+PA+R+YIPKK+GK  RPLGI +++DKLVQEVVRM+LE+I
Sbjct  61   MSLPRINRIIESIRNRTYQPKPAKRKYIPKKNGK-LRPLGITSTDDKLVQEVVRMILEAI  119

Query  121  YEPTFLDSSHGFRPNRSCHTALARMQRSFNGVKWFVEGDIKAYFDTIDHHMLVNILRRRI  180
            YEPTF ++SHGFRP+RSCHTAL++++++F GV W+VEGDIKA FD +DHH+LV++LR+RI
Sbjct  120  YEPTFSNNSHGFRPKRSCHTALTQVKKNFTGVTWIVEGDIKACFDNFDHHVLVELLRKRI  179

Query  181  QDENFISLIWKFLRAGYLEDWQYNATYSGSPQGSGASPLLANLYLHELDLYMEEYKQRFD  240
             DE FI+LIWKFL+AGY+E+WQYN TYSG PQGSG SP+ AN+YL ELD YM+EYK+++D
Sbjct  180  SDEAFIGLIWKFLKAGYMEQWQYNCTYSGVPQGSGISPICANIYLSELDNYMQEYKEKYD  239

Query  241  KGNRRQAGKDYGRAQRTHQYRKVKYDRLWLTLTDEEKKAAQ--REIRALRKRMLECPAND  298
              +  +        + +++YRK +      +L + EK +++  +E++  R++ ++    +
Sbjct  240  -CEPERRRTTREYERASRRYRKAR-----KALMGAEKSTPELVKEFKDSRRKKMNQHYYN  293

Query  299  PMDGTYRRIQYVRYCDDFLVGIIGSKTDAEKVKADICRFLSDKLKLTLSPEKTLITHGQD  358
            P +  +++IQY RY DDF++G+IGSK DAEK+K D+  FL +KL L +S EKT +TH+  
Sbjct  294  PFEEGFKKIQYNRYADDFVIGVIGSKKDAEKIKEDVKIFLQEKLHLEMSEEKTKVTHSSK  353

Query  359  KARFLGYDIAVCQDNTTRRTSRGQ-SRVHSGKVKLYVPKDKWVGKLREYGVLKVA-SDGN  416
              R+LGYD+ V + +  +R   G+  RV  GKV LY+PK+KW+ K  E G ++V  +++ 
Sbjct  354  PVRYLGYDFKVIHSKNMKRCKNGDMKRVWYGKVFLYMPKEKWIKKAMERGAIQVKRNNDT  413

Query  417  GKEKWTPQPRTDFMGLEPREIVNMYNAQLRGIYNYFRMANNASVLNKFHYVMKYSLYKTL  476
            GKE W P PR D+M     EIV+ +N+++RG+YN++R+A+N + L+K+ Y+++YS+ KTL
Sbjct  414  GKEMWRPMPRKDLMNRSDAEIVSTFNSEIRGLYNFYRIAENVGALHKYYYMVRYSMLKTL  473

Query  477  AGKFRTTVSKINAKYSRDGAFIVEYMTKSGIRRVTFYQDGFPRIVAPLPANVDYQPEYVV  536
            AGK RT VS I+ +   +G + + Y T  G +   FY+DGF +         D  P Y  
Sbjct  474  AGKHRTNVSVIKKRHMVNGVLRIPYDTTKGRKYCEFYHDGFRKHSDGYDNVADVMPSY-R  532

Query  537  NYEPKE-LFYRMKAARCELCGKEHVLVSSHQVKRLKDLTGSHPWERVMLKMRRKTLIVCN  595
            +Y++++ +  R+KA+ CE+CG +   +  H+V+ LK L G +  E+ MLKMRRK+L +C 
Sbjct  533  KYDSRHTIVNRIKAGVCEICGEHADYLCMHHVRTLKSLKGRDIFEQKMLKMRRKSLALCP  592

Query  596  ECHRAIHSV  604
            +C   +H  
Sbjct  593  DCFELLHET  601

4) LL3_02382 in NC_017190


> NC_021994_R1|7|G7|529233401|YP_008394213.1|Enterococcus_faecium_Aus0085|+|4653..6470|-|EFAU085_00689|HNH 
endonuclease domain 
protein
Length=605

 Score =  485 bits (1827),  Expect = 5e-138, Method: Compositional matrix adjust.
 Identities = 290/607 (48%), Positives = 427/607 (71%), Gaps = 11/607 (1%)

Query  1    MRSPDVVLNNLVSKSKEENYVFDRLYRNLYNPEFYLKAYAKIYAKPGNMTKGSDGKTIDG  60
            MR+P  VL++L  K+   NY ++RLYRNLYNPEFYL AYA+I    G+MT+G DG+T+D 
Sbjct  1    MRNPIHVLKSLEEKASVSNYKYERLYRNLYNPEFYLLAYANIAKSQGSMTQGVDGQTLDN  60

Query  61   FSHKRIDSLIDSLKNETYQPKPSRRVYITKSNGKKRPLGIPSFDDKLVQEVVRMILEAIY  120
             S  RI+ +I+S++N TYQPKP++R YI K NGK RPLGI S DDKLVQEVVRMILEAIY
Sbjct  61   MSLPRINRIIESIRNRTYQPKPAKRKYIPKKNGKLRPLGITSTDDKLVQEVVRMILEAIY  120

Query  121  EGTFQDSSHGFRPNRSCHTALKQVKHSFTGVRWFIEGDIESFFDHIDHHTLISILAKRIR  180
            E TF ++SHGFRP+RSCHTAL QVK +FTGV W++EGDI + FD++DHH L+ +L KRI 
Sbjct  121  EPTFSNNSHGFRPKRSCHTALTQVKKNFTGVTWIVEGDIKACFDNFDHHVLVELLRKRIS  180

Query  181  DSKFIRLIWKFLRAGFINDWKFHSTYSGTPQGGIISPLLSNIYLNELDKYLRDYASGFNK  240
            D  FI LIWKFL+AG++++W+++ TYSG PQG+ ISP+ +NIYL+ELD+Y+++Y   ++ 
Sbjct  181  DEAFIGLIWKFLKAGYMEQWQYNCTYSGVPQGSGISPICANIYLSELDNYMQEYKEKYDC  240

Query  241  AKKRATNKEYKRREYLVY-KHRKKLKACWDelplerkreelrTYKSLKQKLLAVDFADPM  299
               R        R    Y K RK L +     +     E ++ +K  ++K +  ++ +P 
Sbjct  241  EPERRRTTREYERASRRYRKARKALMG-----AEKSTPELVKEFKDSRRKKMNQHYYNPF  295

Query  300  DTNYKRIQYVRYADDFIVGIIGSKKDCLKIKEDLTVFLNKNLKLNLSQEKTLITNSSKKA  359
            +  +K+IQY RYADDF++G+IGSKKD  KIKED+ +FL+ +L L++S+EKT +T+SSK  
Sbjct  296  EEGFKKIQYNRYADDFVIGVIGSKKDAEKIKEDVKIFLQEKLHLEMSEEKTKVTHSSKPV  355

Query  360  RFLGYDIQIKRSSHTKTDKNGNLRKTQNLRCKLYMPAEKWINKLKEYKALKI-----TAD  414
            R+LGYD+++ +S + K  KNG++++    +  LYMP EKWI+K  E  A+++     T+ 
Sbjct  356  RYLGYDFKVIHSKNMKRCKNGDMKRVWYGKVFLYMPKEKWIKKAMERGAIQVKRNNDTGK  415

Query  415  GKWKAAHRTYLINHDDLEIINMYNSEIRGMYNYYKLAHNVHTLNDFYYFMKYSFLRTLGA  474
              W++  R  L+N+ D EI++ +NSEIRG+YN+Y++A+NV +L+ +YY ++YS L+TL++
Sbjct  416  EMWRPMPRKDLMNRSDAEIVSTFNSEIRGLYNFYRIAENVGALHKYYYMVRYSMLKTLAG  475

Query  475  KYKASVASIYSRFRLNGKLGIAYKTKAGTKIRYFYREGFKRVDNEADIRCDTLPNFVRYV  534
            K +++V+ I  R  +NG L I+Y T  G K   FY++GF++  +  D   D +P++ +Y 
Sbjct  476  KHRTNVSVIKKRHMVNGVLRIPYDTTKGRKYCEFYHDGFRKHSDGYDNVADVMPSYRKYD  535

Query  535  GRTSLIDRLSAKKCEYCGKADVAIEMHHVRKLKDLKGKTLWEQHMIARQRKTLALCVDCH  594
            +R ++++R+ A  CE CG     + MHHVR LK LKG+ + EQ M+  +RK+LALC DC 
Sbjct  536  SRHTIVNRIKAGVCEICGEHADYLCMHHVRTLKSLKGRDIFEQKMLKMRRKSLALCPDCF  595

Query  595  RDLHNGK  601
              LH+ K
Sbjct  596  ELLHETK  602

5) DSY4554 in NC_007907


> NC_021994_R1|7|G7|529233401|YP_008394213.1|Enterococcus_faecium_Aus0085|+|4653..6470|-|EFAU085_00689|HNH 
endonuclease domain 
protein
Length=605

 Score =  458 bits (1725),  Expect = 5e-130, Method: Compositional matrix adjust.
 Identities = 294/606 (49%), Positives = 417/606 (69%), Gaps = 7/606 (1%)

Query  1    MRNPINMLSSLQNHSSDKSYTFERLYRNLYNRELFLLAYQNIYASQGNMTKGTDGKTIDA  60
            MRNPI++L SL++ +S  +Y +ERLYRNLYN E++LLAY NI  SQG+MT+G DG+T+D 
Sbjct  1    MRNPIHVLKSLEEKASVSNYKYERLYRNLYNPEFYLLAYANIAKSQGSMTQGVDGQTLDN  60

Query  61   MSLNRIDGIIASLKDESYQPQPSRRTYIPKKNGKLRPLGIPSFDDKLVQECVRLLLEAVY  120
            MSL RI+ II S+++ +YQP+P++R YIPKKNGKLRPLGI S DDKLVQE VR++LEA+Y
Sbjct  61   MSLPRINRIIESIRNRTYQPKPAKRKYIPKKNGKLRPLGITSTDDKLVQEVVRMILEAIY  120

Query  121  EGSFAKTSHGFRPNHSCHTALSQVQVCFTGVKWFVEGDIKGFFDNINHEVMIGILAEHIK  180
            E +F++ SHGFRP++SCHTAL+QV+  FTGV W+VEGDIK+ FDN++H+V++ +L  +I 
Sbjct  121  EPTFSNNSHGFRPKRSCHTALTQVKKNFTGVTWIVEGDIKACFDNFDHHVLVELLRKRIS  180

Query  181  DERFLRLIRKFLKAGYLEDWQYHNTYSGTPQGGIISPILANIYLDKLDRYMEELKKRFDK  240
            DE F+ LI+KFLKAGY+E+WQY+ TYSG PQG+ ISPI ANIYL  LD YM+E K ++D 
Sbjct  181  DEAFIGLIWKFLKAGYMEQWQYNCTYSGVPQGSGISPICANIYLSELDNYMQEYKEKYDC  240

Query  241  GAVRAVYPETYELEKKRGVLAKKLRNT--NSEEEKQVLTEKIREIDRKKLTIPYSDPFDT  298
             + R      YE   +R    +K R++   +E     L   +++  RKK+   Y +PF+ 
Sbjct  241  EPERRRTTREYERASRR---YRKARKALMGAEKSTPELVKEFKDSRRKKMNQHYYNPFEE  297

Query  299  SFKRLQYVRYADDFLIGVIGSKEDAIAIKEQVKAFVADTLILELSDEKTLITHSEKRARF  358
            +FK++QY RYADDF+IGVIGSK DA  IKE+VK F+ + L LE+S+EKT +THS K  R+
Sbjct  298  GFKKIQYNRYADDFVIGVIGSKKDAEKIKEDVKIFLQEKLHLEMSEEKTKVTHSSKPVRY  357

Query  359  LGYDIYVRRSAATKKDKTGRLCRHLNGTVCLEMPTELMRKKLLEYSAMTIEKTV-YGKDN  417
            LGYD+ V +S   K+ K G + R   G V L MP E   KK +E +A+ + +    GK+ 
Sbjct  358  LGYDFKVIHSKNMKRCKNGDMKRVWYGKVFLYMPKEKWIKKAMERGAIQVKRNNDTGKEM  417

Query  418  WKAKARYYLKDNDDLEILDQYNSEIRGFRNYYRIANNASFASSFGYIMQYSMFKTFATKY  477
            W++ +R  L +  D EI+  +NSEIRG+ N+YRIA+N +    + Y+++YSM+KT+A K 
Sbjct  418  WRPMPRKDLMNRSDAEIVSTFNSEIRGLYNFYRIAENVGALHKYYYMVRYSMLKTLAGKH  477

Query  478  RTTMRRMIEKLRTGKNFGVRFTDKKGKAKTRLFYNEGFARKPLQKNAVVDVIPQTVMYSS  537
            RT +  +  +      + + +   KG+ K   FY++GF + +   + V DV+P    Y S
Sbjct  478  RTNVSVIKKRHMVNGVLRIPYDTTKGR-KYCEFYHDGFRKHSDGYDNVADVMPSYRKYDS  536

Query  538  KTSLMARLSAGQCELCGKTDCEIEIHHVRKLKDLKGKSYWERFMIARNRKTLALCLDCHE  597
            + +++ R+ AG CE+CG     + +HHVR LK LKG+   E+ M+   RK+LALC DC E
Sbjct  537  RHTIVNRIKAGVCEICGEHADYLCMHHVRTLKSLKGRDIFEQKMLKMRRKSLALCPDCFE  596

Query  598  KLHSGK  603
             LH  K
Sbjct  597  LLHETK  602

6) MC28_E169 in NC_018687


> NC_021994_R1|7|G7|529233401|YP_008394213.1|Enterococcus_faecium_Aus0085|+|4653..6470|-|EFAU085_00689|HNH 
endonuclease domain 
protein
Length=605

 Score =  449 bits (1690),  Expect = 3e-127, Method: Compositional matrix adjust.
 Identities = 274/608 (46%), Positives = 414/608 (69%), Gaps = 12/608 (1%)

Query  8    MRNPHYVLSNLASKANNTEYKYKRLYRNLYNIEFYLLAYHKINAKEGNLTKGADGKTIDG  67
            MRNP  VL +L  KA+ ++YKY RLYRNLYN EFYLLAY +I   +G++T+G DG+T+D 
Sbjct  1    MRNPIHVLKSLEEKASVSNYKYERLYRNLYNPEFYLLAYANIAKSQGSMTQGVDGQTLDN  60

Query  68   MSIERIQNIIEELREQSYRPHPVKRVYIPKAKQGKRPLGIPSFDDKLIQEVLRLILESIY  127
            MS+ RI+ IIE +R+++Y+P P KR YIPK +   RPLGI S DDKL+QEV+R+ILE+IY
Sbjct  61   MSLPRINRIIESIRNRTYQPKPAKRKYIPKKNGKLRPLGITSTDDKLVQEVVRMILEAIY  120

Query  128  EPQFLETSHGFRPKRSCHTAIIKIQRRFTGVKWFVEGDIKGFFDNINHHTLIGILRRRID  187
            EP F + SHGFRPKRSCHTA+ ++++ FTGV W+VEGDIK+ FDN++HH L+ +LR+RI 
Sbjct  121  EPTFSNNSHGFRPKRSCHTALTQVKKNFTGVTWIVEGDIKACFDNFDHHVLVELLRKRIS  180

Query  188  DEKFINLIWKFLKAGYLEDWRYHKTYSGVPQGGIISPLLANIYLNELDKYAEKYKKIFDS  247
            DE FI LIWKFLKAGY+E+W+Y+ TYSGVPQG+ ISP+ ANIYL+ELD+Y + YK  +D 
Sbjct  181  DEAFIGLIWKFLKAGYMEQWQYNCTYSGVPQGSGISPICANIYLSELDNYMQEYKEKYDC  240

Query  248  QTTKRRRPIEYKRIQYKVSDERKWLNENWSSLSKEQRRQKL-KSIREKQKILSSMNCTDP  306
            +      P   +  +      R+  +   + ++ E+    L K +++ ++   + +  +P
Sbjct  241  E------PERRRTTREYERASRRYRKARKALMGAEKSTPELVKEFKDSRRKKMNQHYYNP  294

Query  307  MDGNFRRFNYVRYADDWIVGIIGSKQNAEDVKKDFANYlkselkldlslektlVTNSKKK  366
             +  F++++Y RYADD ++G+IGSK++AE +K D   +L+  L L++S EKT VT+S K 
Sbjct  295  FEEGFKKIQYNRYADDFVIGVIGSKKDAEKIKEDVKIFLQEKLHLEMSEEKTKVTHSSKP  354

Query  367  VRFLGYDLTVQRSSAIKKDKNGIPKRTYNGGVKIYVPHEKWVSSLLEKGALKIRPDG---  423
            VR+LGYD+ V +S  +K+ KNG  KR   G V +Y+P EKW+   +E+GA++++ +    
Sbjct  355  VRYLGYDFKVIHSKNMKRCKNGDMKRVWYGKVFLYMPKEKWIKKAMERGAIQVKRNNDTG  414

Query  424  --RWKILHRNTLIRLDDLEILSTYNAEIRGLYNYYCIANNACVLNKFKYVMEYSMYKTFA  481
               W+ + R+ L+   D EI+ST+N+EIRGLYN+Y IA+N   L+K+ Y++ YSM KT+A
Sbjct  415  KEMWRPMPRKDLMNRSDAEIVSTFNSEIRGLYNFYRIAENVGALHKYYYMVRYSMLKTLA  474

Query  482  SKYRKSKRKIIDKYSINGNFGVKYIVKGEEKIRFLYNEGFKRKRPVTEMKTDYLPTIMQY  541
            +K R +   I  +  +NG + + Y      K   +Y++GF++     +  +D +P+  +Y
Sbjct  475  GKHRTNVSVIKKRHMVNGVLRIPYDTTKGRKYCEFYHDGFRKHSDGYDNVADVMPSYRKY  534

Query  542  KGRTSLISRLEAQTCEICKTEEKPFEVHHVRKLKDLKGKKRWEQRMIARRRKTLVVCLKC  601
             +R ++++R+ A  CEIC  +   + +HHVR LK LKG+   EQ+M+  RRK+L +C  C
Sbjct  535  DSRHTIVNRIKAGVCEICGEHADYLCMHHVRTLKSLKGRDIFEQKMLKMRRKSLALCPDC  594

Query  602  HRDIHNGK  609
               +H+ K
Sbjct  595  FELLHETK  602

7) H175_233p124 in NC_020394


> NC_021994_R1|7|G7|529233401|YP_008394213.1|Enterococcus_faecium_Aus0085|+|4653..6470|-|EFAU085_00689|HNH 
endonuclease domain 
protein
Length=605

 Score =  448 bits (1688),  Expect = 5e-127, Method: Compositional matrix adjust.
 Identities = 281/611 (46%), Positives = 431/611 (71%), Gaps = 15/611 (2%)

Query  1    MRNPNAVLDNLNKKTTNPAYKFERLYRNLYNQEFYFAAYQKIYAKEGNMTRGTDGHTIDG  60
            MRNP  VL +L+ K++ + YK+ERLYRNLYN EFY+ AY +I   +G+MT+G DG+T+D 
Sbjct  1    MRNPIHVLKSLEEKASVSNYKYERLYRNLYNPEFYLLAYANIAKSQGSMTQGVDGQTLDN  60

Query  61   MSLERIDKIIERIKNQSYQPAPSRRVYINKGQNRGKRPLGIPSIDDKLVQEIVRNILEAV  120
            MSL RI++IIE I+N++YQP P++R YI K + +  RPLGI S DDKLVQE+VR ILEA+
Sbjct  61   MSLPRINRIIESIRNRTYQPKPAKRKYIPKKNGK-LRPLGITSTDDKLVQEVVRMILEAI  119

Query  121  FEPTFSNNSHGFRRNRSCHTALTQATKIFKGVKWWVEGDIKGFFDNIDHHilikllkrki  180
            +EPTFSNNSHGFR +RSCHTALTQ  K F GV W VEGDIK+ FDN+DHH+L+ LL+++I
Sbjct  120  YEPTFSNNSHGFRPKRSCHTALTQVKKNFTGVTWIVEGDIKACFDNFDHHVLVELLRKRI  179

Query  181  kDEKFINLIWKFLRAGYLEDWKFNNTYSGTPQGGIISPILSNIYLNELDKYIEEYKTLFD  240
             DE FI LIWKFL+AGY+E+W++N TYSG PQG+ ISPI +NIYL+ELD+Y++EYK  +D
Sbjct  180  SDEAFIGLIWKFLKAGYMEQWQYNCTYSGVPQGSGISPICANIYLSELDNYMQEYKEKYD  239

Query  241  KGTRRQNNIVYTQKYKRLWYLKKKFADRKVLAPHNELTEITSEVKRLQKDIRTMSSVELM  300
                R+      ++  R +Y K +   + ++++++   E+  E K  ++        +  
Sbjct  240  CEPERRRTTREYERASR-RYRKAR---KALMGAEKSTPELVKEFKDSRRKKMNQHYYNPF  295

Query  301  DSSFKRIQYVRYADDFLIGIIGSKQDAEEVKKDLTAFLKNKLNLELSSEKTLITHGKMKA  360
            + +FK+IQY RYADDF+IG+IGSK+DAE +K D+  FL++KL+LE+S EKT +TH+    
Sbjct  296  EEGFKKIQYNRYADDFVIGVIGSKKDAEKIKEDVKIFLQEKLHLEMSEEKTKVTHSSKPV  355

Query  361  RFLGYDVTISNLQAVYKGSNSRIAK-RYASNKCEIYMPKEKWIGklkelkvlkiekDSS-  418
            R+LGYD  + + + + +  N+ + + +Y+  K  +YMPKEKWI K  E   +++ +++  
Sbjct  356  RYLGYDFKVIHSKNMKRCKNGDMKRVWYG--KVFLYMPKEKWIKKAMERGAIQVKRNNDT  413

Query  419  ----WKSIHRAELINSDNLEILSIYNSEIRGLYNYYKLAKNVHSLQKFRYIMKFSMVKTF  474
                W+++ R +L+N  + EI+S +NSEIRGLYN+Y++A NV +L+K+ Y++++SM+KT+
Sbjct  414  GKEMWRPMPRKDLMNRSDAEIVSTFNSEIRGLYNFYRIAENVGALHKYYYMVRYSMLKTL  473

Query  475  ANKYKLSVSKIMKKFNHEGNFRISYTTKTGQKHRYFYNEPLKRVYENPTTNKEIDIVPNT  534
            A K + +VS I K+   +G +RI+Y T  G+K   FY++ +++  ++   ++  D++P+ 
Sbjct  474  AGKHRTNVSVIKKRHMVNGVLRIPYDTTKGRKYCEFYHDGFRK--HSDGYDNVADVMPSY  531

Query  535  MIYAGRNSLIRRLQASKCEWCQTENTAIEMHHVKKLKELKGKQLWERIMIARNRKTLALC  594
              Y +R++++ R++A+ CE C  +   + MHHV+ LK LKG+++ E+ M+   RK+LALC
Sbjct  532  RKYDSRHTIVNRIKAGVCEICGEHADYLCMHHVRTLKSLKGRDIFEQKMLKMRRKSLALC  591

Query  595  KKCHVDLHAGR  605
              C   LH  +
Sbjct  592  PDCFELLHETK  602

8) DSY0050 in NC_007907


> NC_021994_R1|7|G7|529233401|YP_008394213.1|Enterococcus_faecium_Aus0085|+|4653..6470|-|EFAU085_00689|HNH 
endonuclease domain 
protein
Length=605

 Score =  445 bits (1678),  Expect = 3e-126, Method: Compositional matrix adjust.
 Identities = 287/596 (49%), Positives = 407/596 (69%), Gaps = 7/596 (1%)

Query  1    MQNHSSDRSYTFERLYRNLYNRELFLLAYQNIYASQGNMTKGTDGKTIDAMSLNRIDGII  60
            +++ +S  +Y +ERLYRNLYN E++LLAY NI  SQG+MT+G DG+T+D MSL RI+ II
Sbjct  11   LEEKASVSNYKYERLYRNLYNPEFYLLAYANIAKSQGSMTQGVDGQTLDNMSLPRINRII  70

Query  61   ASLKDESYQPQPSRRTYIPKKNGKLRPLGIPSFDDKLVQECVRLLLEAVYEGSFAKTSHG  120
             S+++ +YQP+P++R YIPKKNGKLRPLGI S DDKLVQE VR++LEA+YE +F++ SHG
Sbjct  71   ESIRNRTYQPKPAKRKYIPKKNGKLRPLGITSTDDKLVQEVVRMILEAIYEPTFSNNSHG  130

Query  121  FRPNHSCHTALSQVQVCFTGVKWFVEGDIKGFFDNINHEVMIGILAEHIKDERFLRLIRK  180
            FRP++SCHTAL+QV+  FTGV W+VEGDIK+ FDN++H+V++ +L  +I DE F+ LI+K
Sbjct  131  FRPKRSCHTALTQVKKNFTGVTWIVEGDIKACFDNFDHHVLVELLRKRISDEAFIGLIWK  190

Query  181  FLKAGYLEDWQYHNTYSGTPQGGIISPILANIYLDKLDRYMEELKKRFDKGKARAVYPET  240
            FLKAGY+E+WQY+ TYSG PQG+ ISPI ANIYL  LD YM+E K ++D    R      
Sbjct  191  FLKAGYMEQWQYNCTYSGVPQGSGISPICANIYLSELDNYMQEYKEKYDCEPERRRTTRE  250

Query  241  YELEKKRGVLAKKLRNT--NSEEEKQVLTEKIREIDRKKLTIPYSDPFDTSFKRLQYVRY  298
            YE   +R    +K R++   +E     L   +++  RKK+   Y +PF+ +FK++QY RY
Sbjct  251  YERASRR---YRKARKALMGAEKSTPELVKEFKDSRRKKMNQHYYNPFEEGFKKIQYNRY  307

Query  299  ADDFLIGVIGSKEDAIAIKEQVKAFVADMLILELSDEKTLITHSEKRARFLGYDIYVRRS  358
            ADDF+IGVIGSK DA  IKE+VK F+ + L LE+S+EKT +THS K  R+LGYD+ V +S
Sbjct  308  ADDFVIGVIGSKKDAEKIKEDVKIFLQEKLHLEMSEEKTKVTHSSKPVRYLGYDFKVIHS  367

Query  359  AATKKDKTGRLCRHLNGTVCLEMPTELMRKKLLEYGAMTIEKTV-YGKDNWKAKARYYLK  417
               K+ K G + R   G V L MP E   KK +E GA+ + +    GK+ W++ +R  L 
Sbjct  368  KNMKRCKNGDMKRVWYGKVFLYMPKEKWIKKAMERGAIQVKRNNDTGKEMWRPMPRKDLM  427

Query  418  DNDDLEILDQYNSEIRGFRNYYRIANNAAHASSFGYIMQYSMFKTFATKYRTTMRRMIGK  477
            +  D EI+  +NSEIRG+ N+YRIA+N +    + Y+++YSM+KT+A K RT +  +  +
Sbjct  428  NRSDAEIVSTFNSEIRGLYNFYRIAENVGALHKYYYMVRYSMLKTLAGKHRTNVSVIKKR  487

Query  478  LRTGKNFGVRFTDKKGKTKTRLFYNEGFARKPLQKNAVVDVIPKTVMYSSKTSLMARLSA  537
                  + + +   KG+ K   FY++GF + +   + V DV+P    Y S+ +++ R+ A
Sbjct  488  HMVNGVLRIPYDTTKGR-KYCEFYHDGFRKHSDGYDNVADVMPSYRKYDSRHTIVNRIKA  546

Query  538  GQCELCGKTDCEIEIHHVRKLKDLKGKSYWERFMIARNRKTLALCLDCHEKLHSGK  593
            G CE+CG     + +HHVR LK LKG+   E+ M+   RK+LALC DC E LH  K
Sbjct  547  GVCEICGEHADYLCMHHVRTLKSLKGRDIFEQKMLKMRRKSLALCPDCFELLHETK  602

9) DSY4652 in NC_007907


> NC_021994_R1|7|G7|529233401|YP_008394213.1|Enterococcus_faecium_Aus0085|+|4653..6470|-|EFAU085_00689|HNH 
endonuclease domain 
protein
Length=605

 Score =  445 bits (1678),  Expect = 3e-126, Method: Compositional matrix adjust.
 Identities = 287/596 (49%), Positives = 407/596 (69%), Gaps = 7/596 (1%)

Query  1    MQNHSSDRSYTFERLYRNLYNRELFLLAYQNIYASQGNMTKGTDGKTIDAMSLNRIDGII  60
            +++ +S  +Y +ERLYRNLYN E++LLAY NI  SQG+MT+G DG+T+D MSL RI+ II
Sbjct  11   LEEKASVSNYKYERLYRNLYNPEFYLLAYANIAKSQGSMTQGVDGQTLDNMSLPRINRII  70

Query  61   ASLKDESYQPQPSRRTYIPKKNGKLRPLGIPSFDDKLVQECVRLLLEAVYEGSFAKTSHG  120
             S+++ +YQP+P++R YIPKKNGKLRPLGI S DDKLVQE VR++LEA+YE +F++ SHG
Sbjct  71   ESIRNRTYQPKPAKRKYIPKKNGKLRPLGITSTDDKLVQEVVRMILEAIYEPTFSNNSHG  130

Query  121  FRPNHSCHTALSQVQVCFTGVKWFVEGDIKGFFDNINHEVMIGILAEHIKDERFLRLIRK  180
            FRP++SCHTAL+QV+  FTGV W+VEGDIK+ FDN++H+V++ +L  +I DE F+ LI+K
Sbjct  131  FRPKRSCHTALTQVKKNFTGVTWIVEGDIKACFDNFDHHVLVELLRKRISDEAFIGLIWK  190

Query  181  FLKAGYLEDWQYHNTYSGTPQGGIISPILANIYLDKLDRYMEELKKRFDKGKARAVYPET  240
            FLKAGY+E+WQY+ TYSG PQG+ ISPI ANIYL  LD YM+E K ++D    R      
Sbjct  191  FLKAGYMEQWQYNCTYSGVPQGSGISPICANIYLSELDNYMQEYKEKYDCEPERRRTTRE  250

Query  241  YELEKKRGVLAKKLRNT--NSEEEKQVLTEKIREIDRKKLTIPYSDPFDTSFKRLQYVRY  298
            YE   +R    +K R++   +E     L   +++  RKK+   Y +PF+ +FK++QY RY
Sbjct  251  YERASRR---YRKARKALMGAEKSTPELVKEFKDSRRKKMNQHYYNPFEEGFKKIQYNRY  307

Query  299  ADDFLIGVIGSKEDAIAIKEQVKAFVADMLILELSDEKTLITHSEKRARFLGYDIYVRRS  358
            ADDF+IGVIGSK DA  IKE+VK F+ + L LE+S+EKT +THS K  R+LGYD+ V +S
Sbjct  308  ADDFVIGVIGSKKDAEKIKEDVKIFLQEKLHLEMSEEKTKVTHSSKPVRYLGYDFKVIHS  367

Query  359  AATKKDKTGRLCRHLNGTVCLEMPTELMRKKLLEYGAMTIEKTV-YGKDNWKAKARYYLK  417
               K+ K G + R   G V L MP E   KK +E GA+ + +    GK+ W++ +R  L 
Sbjct  368  KNMKRCKNGDMKRVWYGKVFLYMPKEKWIKKAMERGAIQVKRNNDTGKEMWRPMPRKDLM  427

Query  418  DNDDLEILDQYNSEIRGFRNYYRIANNAAHASSFGYIMQYSMFKTFATKYRTTMRRMIGK  477
            +  D EI+  +NSEIRG+ N+YRIA+N +    + Y+++YSM+KT+A K RT +  +  +
Sbjct  428  NRSDAEIVSTFNSEIRGLYNFYRIAENVGALHKYYYMVRYSMLKTLAGKHRTNVSVIKKR  487

Query  478  LRTGKNFGVRFTDKKGKTKTRLFYNEGFARKPLQKNAVVDVIPKTVMYSSKTSLMARLSA  537
                  + + +   KG+ K   FY++GF + +   + V DV+P    Y S+ +++ R+ A
Sbjct  488  HMVNGVLRIPYDTTKGR-KYCEFYHDGFRKHSDGYDNVADVMPSYRKYDSRHTIVNRIKA  546

Query  538  GQCELCGKTDCEIEIHHVRKLKDLKGKSYWERFMIARNRKTLALCLDCHEKLHSGK  593
            G CE+CG     + +HHVR LK LKG+   E+ M+   RK+LALC DC E LH  K
Sbjct  547  GVCEICGEHADYLCMHHVRTLKSLKGRDIFEQKMLKMRRKSLALCPDCFELLHETK  602

10) Odosp_0220 in NC_015160


> NC_021994_R1|7|G7|529233401|YP_008394213.1|Enterococcus_faecium_Aus0085|+|4653..6470|-|EFAU085_00689|HNH 
endonuclease domain 
protein
Length=605

 Score =  437 bits (1646),  Expect = 1e-123, Method: Compositional matrix adjust.
 Identities = 267/597 (45%), Positives = 408/597 (69%), Gaps = 7/597 (1%)

Query  1    MRNPEQVLNILAGHSNEPEYKYERLYRILFNEQMFFAAYQRMYAKPGNMTPGTDGKTEDE  60
            MRNP +VL+ L   ++ ++YKYERLYR L+N + ++ AY  +    G+MT G DG+T D+
Sbjct  1    MRNPIHVLKSLEEKASVSNYKYERLYRNLYNPEFYLLAYANIAKSQGSMTQGVDGQTLDN  60

Query  61   MSIDRINKLIESIKDETYSPNPAKRIYIPKKNGKMRPLGIPSFEDKLVQEAVRMVLEAIY  120
            MS+ RIN++IESI++ TY P+PAKR YIPKKNGK+RPLGI S +DKLVQE VRM+LEAIY
Sbjct  61   MSLPRINRIIESIRNRTYQPKPAKRKYIPKKNGKLRPLGITSTDDKLVQEVVRMILEAIY  120

Query  121  EGHFEWTSHGFRPNRSCHTALKSLQNNFNGAKWFIEGDIKGFFDNIDHDVLIEIMKGRIA  180
            E  F   SHGFRP+RSCHTAL  +++NF G  W++EGDIK+ FDN+DH+VL+E+++ RI+
Sbjct  121  EPTFSNNSHGFRPKRSCHTALTQVKKNFTGVTWIVEGDIKACFDNFDHHVLVELLRKRIS  180

Query  181  DDRFLRLIRKFLNAGYMEEWQFNKTYSGTPQGGIISPVLANIYLDKFDKYMNEYANKFNK  240
            D+ F+ LI+KFL+AGYME+WQ+N TYSG PQG+ ISP+ ANIYL  +D+YM+EY +K++ 
Sbjct  181  DEAFIGLIWKFLKAGYMEQWQYNCTYSGVPQGSGISPICANIYLSELDNYMQEYKEKYDC  240

Query  241  GTVRSRNKDICKLNSRVHYLKRRINEVEDVNVRTRMVEELHEKQKRILTMPSGNDMDRNF  300
               R R        SR +Y K R   +   +    +V E+ + +++ +     N  +  F
Sbjct  241  EPERRRTTREYERASR-RYRKARKALMGAEKSTPELVKEFKDSRRKKMNQHYYNPFEEGF  299

Query  301  RRLRYLRYADDFLIGVIGTKNECETIKADITKFMQEKLRLEMSQEKTLITNAQDSAKFLG  360
            ++++Y RYADDF+IGVIG+K++ E IK D+  F+QEKL+LEMS+EKT +T++  + ++LG
Sbjct  300  KKIQYNRYADDFVIGVIGSKKDAEKIKEDVKIFLQEKLHLEMSEEKTKVTHSSKPVRYLG  359

Query  361  YEIYVRKDYATKRNSNGTVRRYFNGNVILHVSREVIKNKLLSLEAMKV--VTKRGKETWV  418
            Y++ V      KR  NG ++R   G+V+L +++E   +K +   A++V      GKE W 
Sbjct  360  YDFKVIHSKNMKRCKNGDMKRVWYGKVFLYMPKEKWIKKAMERGAIQVKRNNDTGKEMWR  419

Query  419  SKGRTYMIDNEAHEIVSQFNTEIRGFYNYYSIANNASALGRSFGCIMKFSMYKTLAQKLN  478
            +  R  +++    EIVS FN+EIRG+YN+Y IA+N +AL + +  ++++SM KTLA K  
Sbjct  420  PMPRKDLMNRSDAEIVSTFNSEIRGLYNFYRIAENVGALHKYY-YMVRYSMLKTLAGKHR  478

Query  479  MSVRKVIETYRKDNLFAVPFVNKGGETKYRVFYNEGYARKTDCETAPSDNLP-YMFKTPS  537
             +V  +      + ++ +P+    G  KY  FY++G+ + +D     +D +P Y    + 
Sbjct  479  TNVSVIKKRHMVNGVLRIPYDTTKG-RKYCEFYHDGFRKHSDGYDNVADVMPSYRKYDSR  537

Query  538  LSLIERLTTKTCELCGKHGE-VVMHHVRTLKELKGKNDWERKMLYMHRKTLVVCAEC  593
             ++++R+ +  CE+CG H++ + MHHVRTLK LKG++  E+KML M+RK+L +C++C
Sbjct  538  HTIVNRIKAGVCEICGEHADYLCMHHVRTLKSLKGRDIFEQKMLKMRRKSLALCPDC  594

11) Odosp_1207 in NC_015160


> NC_021994_R1|7|G7|529233401|YP_008394213.1|Enterococcus_faecium_Aus0085|+|4653..6470|-|EFAU085_00689|HNH 
endonuclease domain 
protein
Length=605

 Score =  437 bits (1646),  Expect = 1e-123, Method: Compositional matrix adjust.
 Identities = 267/597 (45%), Positives = 408/597 (69%), Gaps = 7/597 (1%)

Query  1    MRNPEQVLNILAGHSNEPEYKYERLYRILFNEQMFFAAYQRMYAKPGNMTPGTDGKTEDE  60
            MRNP +VL+ L   ++ ++YKYERLYR L+N + ++ AY  +    G+MT G DG+T D+
Sbjct  1    MRNPIHVLKSLEEKASVSNYKYERLYRNLYNPEFYLLAYANIAKSQGSMTQGVDGQTLDN  60

Query  61   MSIDRINKLIESIKDETYSPNPAKRIYIPKKNGKMRPLGIPSFEDKLVQEAVRMVLEAIY  120
            MS+ RIN++IESI++ TY P+PAKR YIPKKNGK+RPLGI S +DKLVQE VRM+LEAIY
Sbjct  61   MSLPRINRIIESIRNRTYQPKPAKRKYIPKKNGKLRPLGITSTDDKLVQEVVRMILEAIY  120

Query  121  EGHFEWTSHGFRPNRSCHTALKSLQNNFNGAKWFIEGDIKGFFDNIDHDVLIEIMKGRIA  180
            E  F   SHGFRP+RSCHTAL  +++NF G  W++EGDIK+ FDN+DH+VL+E+++ RI+
Sbjct  121  EPTFSNNSHGFRPKRSCHTALTQVKKNFTGVTWIVEGDIKACFDNFDHHVLVELLRKRIS  180

Query  181  DDRFLRLIRKFLNAGYMEEWQFNKTYSGTPQGGIISPVLANIYLDKFDKYMNEYANKFNK  240
            D+ F+ LI+KFL+AGYME+WQ+N TYSG PQG+ ISP+ ANIYL  +D+YM+EY +K++ 
Sbjct  181  DEAFIGLIWKFLKAGYMEQWQYNCTYSGVPQGSGISPICANIYLSELDNYMQEYKEKYDC  240

Query  241  GTVRSRNKDICKLNSRVHYLKRRINEVEDVNVRTRMVEELHEKQKRILTMPSGNDMDRNF  300
               R R        SR +Y K R   +   +    +V E+ + +++ +     N  +  F
Sbjct  241  EPERRRTTREYERASR-RYRKARKALMGAEKSTPELVKEFKDSRRKKMNQHYYNPFEEGF  299

Query  301  RRLRYLRYADDFLIGVIGTKNECETIKADITKFMQEKLRLEMSQEKTLITNAQDSAKFLG  360
            ++++Y RYADDF+IGVIG+K++ E IK D+  F+QEKL+LEMS+EKT +T++  + ++LG
Sbjct  300  KKIQYNRYADDFVIGVIGSKKDAEKIKEDVKIFLQEKLHLEMSEEKTKVTHSSKPVRYLG  359

Query  361  YEIYVRKDYATKRNSNGTVRRYFNGNVILHVSREVIKNKLLSLEAMKV--VTKRGKETWV  418
            Y++ V      KR  NG ++R   G+V+L +++E   +K +   A++V      GKE W 
Sbjct  360  YDFKVIHSKNMKRCKNGDMKRVWYGKVFLYMPKEKWIKKAMERGAIQVKRNNDTGKEMWR  419

Query  419  SKGRTYMIDNEAHEIVSQFNTEIRGFYNYYSIANNASALGRSFGCIMKFSMYKTLAQKLN  478
            +  R  +++    EIVS FN+EIRG+YN+Y IA+N +AL + +  ++++SM KTLA K  
Sbjct  420  PMPRKDLMNRSDAEIVSTFNSEIRGLYNFYRIAENVGALHKYY-YMVRYSMLKTLAGKHR  478

Query  479  MSVRKVIETYRKDNLFAVPFVNKGGETKYRVFYNEGYARKTDCETAPSDNLP-YMFKTPS  537
             +V  +      + ++ +P+    G  KY  FY++G+ + +D     +D +P Y    + 
Sbjct  479  TNVSVIKKRHMVNGVLRIPYDTTKG-RKYCEFYHDGFRKHSDGYDNVADVMPSYRKYDSR  537

Query  538  LSLIERLTTKTCELCGKHGE-VVMHHVRTLKELKGKNDWERKMLYMHRKTLVVCAEC  593
             ++++R+ +  CE+CG H++ + MHHVRTLK LKG++  E+KML M+RK+L +C++C
Sbjct  538  HTIVNRIKAGVCEICGEHADYLCMHHVRTLKSLKGRDIFEQKMLKMRRKSLALCPDC  594

12) Alfi_3211 in NC_018011


> NC_021994_R1|7|G7|529233401|YP_008394213.1|Enterococcus_faecium_Aus0085|+|4653..6470|-|EFAU085_00689|HNH 
endonuclease domain 
protein
Length=605

 Score =  434 bits (1636),  Expect = 6e-123, Method: Compositional matrix adjust.
 Identities = 273/604 (46%), Positives = 400/604 (67%), Gaps = 10/604 (1%)

Query  1    MRSPARVLNSLTKHSQTTEYRFERLYRILFNEEMYYLAYQRIYAKPGNMTQGADGETIDR  60
            MR+P +VL+SL   +  ++Y++ERLYR L+N E Y LAY  I    G+MTQG DG+T+D 
Sbjct  1    MRNPIHVLKSLEEKASVSNYKYERLYRNLYNPEFYLLAYANIAKSQGSMTQGVDGQTLDN  60

Query  61   MSLPRIEKLILSLKDESYSPQPSRRVHIPKKNGKTRPLGVPSFDDKLVQEVVRMVLEAIY  120
            MSLPRI+++I S+++ +Y P+P++R  IPKKNGK RPLG+ S DDKLVQEVVRM+LEAIY
Sbjct  61   MSLPRINRIIESIRNRTYQPKPAKRKYIPKKNGKLRPLGITSTDDKLVQEVVRMILEAIY  120

Query  121  EGHFEDTSHGFRPHRSCHTALNAVQKTFTGKKWFIEGDIKGFFDNVNHDILIDILKERIS  180
            E  F + SHGFRP RSCHTAL  V+K FTG  W++EGDIK+ FDN +H++L+++L+ RIS
Sbjct  121  EPTFSNNSHGFRPKRSCHTALTQVKKNFTGVTWIVEGDIKACFDNFDHHVLVELLRKRIS  180

Query  181  DERSIRLIRKFLRAGYLEQWRFHGTYSGMPQGGIISPVLANIYLDKLDKYMKEYATGFDR  240
            DE  I LI+KFL+AGY+EQW+++ TYSG+PQG+ ISP+ ANIYL  LD+YM+EY   +D 
Sbjct  181  DEAFIGLIWKFLKAGYMEQWQYNCTYSGVPQGSGISPICANIYLSELDNYMQEYKEKYDC  240

Query  241  GNRVRACREYEALTYQK-RLVMRELKTATNDVERKVLVKRLKEIDKTRSAMPCFDPMDGN  299
                R        + ++ R   + L  A +      LVK +K+  + +     ++P +  
Sbjct  241  EPERRRTTREYERASRRYRKARKALMGAEKSTPE--LVKEFKDSRRKKMNQHYYNPFEEG  298

Query  300  FKRLKYVRYADDFLIGiivskvkikddikR---FLADRLALELSDEKTLVTHTEKPAKFL  356
            FK+++Y RYADDF+IG+I SK            FL ++L LE+S+EKT VTH+ KP ++L
Sbjct  299  FKKIQYNRYADDFVIGVIGSKKDAEKIKEDVKIFLQEKLHLEMSEEKTKVTHSSKPVRYL  358

Query  357  GYEVTVRKSNLQKRNKRGSLSRVYGNKVRLKVTTEVIKKKLLELGVLKF--SYHNGHEQW  414
            GY+  V  S+  KR K G + RV   KV L +  E   KK +E G ++   + + G E W
Sbjct  359  GYDFKVIHSKNMKRCKNGDMKRVWYGKVFLYMPKEKWIKKAMERGAIQVKRNNDTGKEMW  418

Query  415  IPKHRSELINNDDLEILDSYNAEIRGFYNYYSIANNASELNTFHYIMQYSMYKTFAGKYR  474
             P  R +L+N  D EI+ ++N+EIRG+YN+Y IA+N + L+ + Y+++YSM KT+AGK R
Sbjct  419  RPMPRKDLMNRSDAEIVSTFNSEIRGLYNFYRIAENVGALHKYYYMVRYSMLKTLAGKHR  478

Query  475  TTVRRICRKYKRNGVFTVGYTVKNGKAKERRLYNEGFKRKRPSYDRSVDRCPNPMPGVST  534
            T V  I ++   NGV+ + Y   +G+ K   +Y++GF++   +YD   D  P+     S 
Sbjct  479  TNVSVIKKRHMVNGVLRIPYDTTKGR-KYCEFYHDGFRKHSDGYDNVADVMPSYRKYDSR  537

Query  535  TSLIDRLKAQKCELCGA-TDNLVMHHVRKLGELKGKENWEKLMIARRRKTMAVCGSCHQK  593
             ++++R+KA  CE+CG  +D L MHHVR L  LKG++  E+ M+  RRK++A+C  C + 
Sbjct  538  HTIVNRIKAGVCEICGEHADYLCMHHVRTLKSLKGRDIFEQKMLKMRRKSLALCPDCFEL  597

Query  594  IHHG  597
            +H+ 
Sbjct  598  LHET  601

13) BF638R_1362 in NC_016776


> NC_021994_R1|7|G7|529233401|YP_008394213.1|Enterococcus_faecium_Aus0085|+|4653..6470|-|EFAU085_00689|HNH 
endonuclease domain 
protein
Length=605

 Score =  431 bits (1623),  Expect = 6e-122, Method: Compositional matrix adjust.
 Identities = 275/597 (47%), Positives = 414/597 (70%), Gaps = 6/597 (1%)

Query  1    MRNPENVLNSLSKHSGNLNYKFERLYRVLFNEEMFYVAYQNIYSKTGNMTAGADGKTIDG  60
            MRNP +VL+SL   ++  NYK+ERLYR L+N E + +AY NI    G+MT G DG+T+D 
Sbjct  1    MRNPIHVLKSLEEKASVSNYKYERLYRNLYNPEFYLLAYANIAKSQGSMTQGVDGQTLDN  60

Query  61   MSIDRVEQLIGSLKNETYQPNPSKRTYIPKKNGKKRPLGIPSFDDKLVQEVVRMILEAIY  120
            MS+ R++++I S++N TYQP+P+KR YIPKKNGK RPLGI S DDKLVQEVVRMILEAIY
Sbjct  61   MSLPRINRIIESIRNRTYQPKPAKRKYIPKKNGKLRPLGITSTDDKLVQEVVRMILEAIY  120

Query  121  EGSFEHTSHGFRPKRSCHTALIDIQKTFTAVKWFIEGDIKGFFDNINHDVLINILRERIA  180
            E +F + SHGFRPKRSCHTAL +++K FT+V W++EGDIK+ FDN++H+VL+++LR RI+
Sbjct  121  EPTFSNNSHGFRPKRSCHTALTQVKKNFTGVTWIVEGDIKACFDNFDHHVLVELLRKRIS  180

Query  181  DERFLRLIRKFLNAGYVEDWVFHRTYSGTPQGGIISPILANIYLDKFDKYIKEYINRFNK  240
            DE F+ LI+KFL+AGY+E+W ++ TYSG PQG+ ISPI ANIYL  +D+Y++EY ++++ 
Sbjct  181  DEAFIGLIWKFLKAGYMEQWQYNCTYSGVPQGSGISPICANIYLSELDNYMQEYKEKYDC  240

Query  241  GVTRKGDARYKLYEQRRYRLAKKLKNEKDVKVRKQMTAEIKRLREERNNYPARNEMDSSI  300
               R+  +R      RRYR A+K     + K   ++  E+K  R  + N    N  + ++
Sbjct  241  EPERRRTTREYERASRRYRKARKALMGAE-KSTPELVKEFKDSRRKKMNQHYYNPFEEGF  299

Query  301  KRLKYVRYADDFLIGITGNLEDCKTVKEDIKNYLNEALKLELSDEKTLITNAQKPAKFLG  360
            K+++Y RYADDF+IG+ G+  D   +KED+K +L+E L LE+S+EKT +T++ KP ++LG
Sbjct  300  KKIQYNRYADDFVIGVIGSKKDAEKIKEDVKIFLQEKLHLEMSEEKTKVTHSSKPVRYLG  359

Query  361  YDVFIRRCNDLRKDKYGKTVRAFGHKPVLYLNFETMRKKLFDYKAARI--AVVNGKEVWK  418
            YD  + + +++++ K G   R    K  LY+  E   KK  +  A ++      GKE+W+
Sbjct  360  YDFKVIHSKNMKRCKNGDMKRVWYGKVFLYMPKEKWIKKAMERGAIQVKRNNDTGKEMWR  419

Query  419  SIVRTYMLNLDDLEIVSQFNAEIRGFYNYYSIANNSYVINSFYHIMSYSMYKVFANkyks  478
            ++ R  ++N  D EIVS FN+EIRG+YN+Y IA+N   ++ +Y ++ YSM K +A K ++
Sbjct  420  PMPRKDLMNRSDAEIVSTFNSEIRGLYNFYRIAENVGALHKYYYMVRYSMLKTLAGKHRT  479

Query  479  svkkillkykknkvFQVAYENSKGKTLYQSFYHDGFKRKKVAGNIYCDTIPRTVSITGGR  538
            +V  I  +   N V++++Y+ +KG+  Y  FYHDGF++   + +   D +P +    ++R
Sbjct  480  NVSVIKKRHMVNGVLRIPYDTTKGRK-YCEFYHDGFRKHSDGYDNVADVMP-SYRKYDSR  537

Query  539  NSLMERLKLQVCELCGATDK-LEMHHVRKLKDLKGKSDWEKKMIARRRKTLAVCSKC  594
            +++++R+K  VCE+CG     L MHHVR LK LKG+   E+KM+  RRK+LA+C+ C
Sbjct  538  HTIVNRIKAGVCEICGEHADYLCMHHVRTLKSLKGRDIFEQKMLKMRRKSLALCPDC  594

14) BF638R_2096 in NC_016776


> NC_021994_R1|7|G7|529233401|YP_008394213.1|Enterococcus_faecium_Aus0085|+|4653..6470|-|EFAU085_00689|HNH 
endonuclease domain 
protein
Length=605

 Score =  431 bits (1623),  Expect = 6e-122, Method: Compositional matrix adjust.
 Identities = 275/597 (47%), Positives = 414/597 (70%), Gaps = 6/597 (1%)

Query  1    MRNPENVLNSLSKHSGNLNYKFERLYRVLFNEEMFYVAYQNIYSKTGNMTAGADGKTIDG  60
            MRNP +VL+SL   ++  NYK+ERLYR L+N E + +AY NI    G+MT G DG+T+D 
Sbjct  1    MRNPIHVLKSLEEKASVSNYKYERLYRNLYNPEFYLLAYANIAKSQGSMTQGVDGQTLDN  60

Query  61   MSIDRVEQLIGSLKNETYQPNPSKRTYIPKKNGKKRPLGIPSFDDKLVQEVVRMILEAIY  120
            MS+ R++++I S++N TYQP+P+KR YIPKKNGK RPLGI S DDKLVQEVVRMILEAIY
Sbjct  61   MSLPRINRIIESIRNRTYQPKPAKRKYIPKKNGKLRPLGITSTDDKLVQEVVRMILEAIY  120

Query  121  EGSFEHTSHGFRPKRSCHTALIDIQKTFTAVKWFIEGDIKGFFDNINHDVLINILRERIA  180
            E +F + SHGFRPKRSCHTAL +++K FT+V W++EGDIK+ FDN++H+VL+++LR RI+
Sbjct  121  EPTFSNNSHGFRPKRSCHTALTQVKKNFTGVTWIVEGDIKACFDNFDHHVLVELLRKRIS  180

Query  181  DERFLRLIRKFLNAGYVEDWVFHRTYSGTPQGGIISPILANIYLDKFDKYIKEYINRFNK  240
            DE F+ LI+KFL+AGY+E+W ++ TYSG PQG+ ISPI ANIYL  +D+Y++EY ++++ 
Sbjct  181  DEAFIGLIWKFLKAGYMEQWQYNCTYSGVPQGSGISPICANIYLSELDNYMQEYKEKYDC  240

Query  241  GVTRKGDARYKLYEQRRYRLAKKLKNEKDVKVRKQMTAEIKRLREERNNYPARNEMDSSI  300
               R+  +R      RRYR A+K     + K   ++  E+K  R  + N    N  + ++
Sbjct  241  EPERRRTTREYERASRRYRKARKALMGAE-KSTPELVKEFKDSRRKKMNQHYYNPFEEGF  299

Query  301  KRLKYVRYADDFLIGITGNLEDCKTVKEDIKNYLNEALKLELSDEKTLITNAQKPAKFLG  360
            K+++Y RYADDF+IG+ G+  D   +KED+K +L+E L LE+S+EKT +T++ KP ++LG
Sbjct  300  KKIQYNRYADDFVIGVIGSKKDAEKIKEDVKIFLQEKLHLEMSEEKTKVTHSSKPVRYLG  359

Query  361  YDVFIRRCNDLRKDKYGKTVRAFGHKPVLYLNFETMRKKLFDYKAARI--AVVNGKEVWK  418
            YD  + + +++++ K G   R    K  LY+  E   KK  +  A ++      GKE+W+
Sbjct  360  YDFKVIHSKNMKRCKNGDMKRVWYGKVFLYMPKEKWIKKAMERGAIQVKRNNDTGKEMWR  419

Query  419  SIVRTYMLNLDDLEIVSQFNAEIRGFYNYYSIANNSYVINSFYHIMSYSMYKVFANkyks  478
            ++ R  ++N  D EIVS FN+EIRG+YN+Y IA+N   ++ +Y ++ YSM K +A K ++
Sbjct  420  PMPRKDLMNRSDAEIVSTFNSEIRGLYNFYRIAENVGALHKYYYMVRYSMLKTLAGKHRT  479

Query  479  svkkillkykknkvFQVAYENSKGKTLYQSFYHDGFKRKKVAGNIYCDTIPRTVSITGGR  538
            +V  I  +   N V++++Y+ +KG+  Y  FYHDGF++   + +   D +P +    ++R
Sbjct  480  NVSVIKKRHMVNGVLRIPYDTTKGRK-YCEFYHDGFRKHSDGYDNVADVMP-SYRKYDSR  537

Query  539  NSLMERLKLQVCELCGATDK-LEMHHVRKLKDLKGKSDWEKKMIARRRKTLAVCSKC  594
            +++++R+K  VCE+CG     L MHHVR LK LKG+   E+KM+  RRK+LA+C+ C
Sbjct  538  HTIVNRIKAGVCEICGEHADYLCMHHVRTLKSLKGRDIFEQKMLKMRRKSLALCPDC  594

15) BT_2602 in NC_004663


> NC_021994_R1|7|G7|529233401|YP_008394213.1|Enterococcus_faecium_Aus0085|+|4653..6470|-|EFAU085_00689|HNH 
endonuclease domain 
protein
Length=605

 Score =  431 bits (1623),  Expect = 6e-122, Method: Compositional matrix adjust.
 Identities = 275/597 (47%), Positives = 414/597 (70%), Gaps = 6/597 (1%)

Query  1    MRNPENVLNSLSKHSGNLNYKFERLYRVLFNEEMFYVAYQNIYSKTGNMTAGADGKTIDG  60
            MRNP +VL+SL   ++  NYK+ERLYR L+N E + +AY NI    G+MT G DG+T+D 
Sbjct  1    MRNPIHVLKSLEEKASVSNYKYERLYRNLYNPEFYLLAYANIAKSQGSMTQGVDGQTLDN  60

Query  61   MSIDRVEQLIGSLKNETYQPNPSKRTYIPKKNGKKRPLGIPSFDDKLVQEVVRMILEAIY  120
            MS+ R++++I S++N TYQP+P+KR YIPKKNGK RPLGI S DDKLVQEVVRMILEAIY
Sbjct  61   MSLPRINRIIESIRNRTYQPKPAKRKYIPKKNGKLRPLGITSTDDKLVQEVVRMILEAIY  120

Query  121  EGSFEHTSHGFRPKRSCHTALIDIQKTFTAVKWFIEGDIKGFFDNINHDVLINILRERIA  180
            E +F + SHGFRPKRSCHTAL +++K FT+V W++EGDIK+ FDN++H+VL+++LR RI+
Sbjct  121  EPTFSNNSHGFRPKRSCHTALTQVKKNFTGVTWIVEGDIKACFDNFDHHVLVELLRKRIS  180

Query  181  DERFLRLIRKFLNAGYVEDWVFHRTYSGTPQGGIISPILANIYLDKFDKYIKEYINRFNK  240
            DE F+ LI+KFL+AGY+E+W ++ TYSG PQG+ ISPI ANIYL  +D+Y++EY ++++ 
Sbjct  181  DEAFIGLIWKFLKAGYMEQWQYNCTYSGVPQGSGISPICANIYLSELDNYMQEYKEKYDC  240

Query  241  GVTRKGDARYKLYEQRRYRLAKKLKNEKDVKVRKQMTAEIKRLREERNNYPARNEMDSSI  300
               R+  +R      RRYR A+K     + K   ++  E+K  R  + N    N  + ++
Sbjct  241  EPERRRTTREYERASRRYRKARKALMGAE-KSTPELVKEFKDSRRKKMNQHYYNPFEEGF  299

Query  301  KRLKYVRYADDFLIGITGNLEDCKTVKEDIKNYLNEALKLELSDEKTLITNAQKPAKFLG  360
            K+++Y RYADDF+IG+ G+  D   +KED+K +L+E L LE+S+EKT +T++ KP ++LG
Sbjct  300  KKIQYNRYADDFVIGVIGSKKDAEKIKEDVKIFLQEKLHLEMSEEKTKVTHSSKPVRYLG  359

Query  361  YDVFIRRCNDLRKDKYGKTVRAFGHKPVLYLNFETMRKKLFDYKAARI--AVVNGKEVWK  418
            YD  + + +++++ K G   R    K  LY+  E   KK  +  A ++      GKE+W+
Sbjct  360  YDFKVIHSKNMKRCKNGDMKRVWYGKVFLYMPKEKWIKKAMERGAIQVKRNNDTGKEMWR  419

Query  419  SIVRTYMLNLDDLEIVSQFNAEIRGFYNYYSIANNSYVINSFYHIMSYSMYKVFANkyks  478
            ++ R  ++N  D EIVS FN+EIRG+YN+Y IA+N   ++ +Y ++ YSM K +A K ++
Sbjct  420  PMPRKDLMNRSDAEIVSTFNSEIRGLYNFYRIAENVGALHKYYYMVRYSMLKTLAGKHRT  479

Query  479  svkkillkykknkvFQVAYENSKGKTLYQSFYHDGFKRKKVAGNIYCDTIPRTVSITGGR  538
            +V  I  +   N V++++Y+ +KG+  Y  FYHDGF++   + +   D +P +    ++R
Sbjct  480  NVSVIKKRHMVNGVLRIPYDTTKGRK-YCEFYHDGFRKHSDGYDNVADVMP-SYRKYDSR  537

Query  539  NSLMERLKLQVCELCGATDK-LEMHHVRKLKDLKGKSDWEKKMIARRRKTLAVCSKC  594
            +++++R+K  VCE+CG     L MHHVR LK LKG+   E+KM+  RRK+LA+C+ C
Sbjct  538  HTIVNRIKAGVCEICGEHADYLCMHHVRTLKSLKGRDIFEQKMLKMRRKSLALCPDC  594

16) OBV_44960 in NC_016048


> NC_021994_R1|7|G7|529233401|YP_008394213.1|Enterococcus_faecium_Aus0085|+|4653..6470|-|EFAU085_00689|HNH 
endonuclease domain 
protein
Length=605

 Score =  431 bits (1622),  Expect = 8e-122, Method: Compositional matrix adjust.
 Identities = 292/611 (48%), Positives = 434/611 (72%), Gaps = 14/611 (2%)

Query  1    MRNPIDVLNSLKTKACNESYHYERLYRNLYNEEFFLLAYQNIYAGEGNMTAGADGKTIDG  60
            MRNPI+VL+SL  KA   +Y YERLYRNLYN EF+LLAY NI  ++G+MT G DG+T+D 
Sbjct  1    MRNPIHVLKSLEEKASVSNYKYERLYRNLYNPEFYLLAYANIAKSQGSMTQGVDGQTLDN  60

Query  61   MGMDRIQTLIESLKNHSYQPNPARRTYIEKKNGKKRPLGIPSFDDKLVQEVVRMILESIY  120
            M++ RI+ +IES++N++YQP+PA+R YI KKNGK RPLGI S DDKLVQEVVRMILE+IY
Sbjct  61   MSLPRINRIIESIRNRTYQPKPAKRKYIPKKNGKLRPLGITSTDDKLVQEVVRMILEAIY  120

Query  121  EPTFSNLSHGFRPNRSCHTALQQIQGTFTGVKWFIEGDICGFFDNIDHTVLINILRRRIH  180
            EPTFSN SHGFRP+RSCHTAL Q++  FTGV W++EGDI + FDN+DH VL+++LR+RI 
Sbjct  121  EPTFSNNSHGFRPKRSCHTALTQVKKNFTGVTWIVEGDIKACFDNFDHHVLVELLRKRIS  180

Query  181  DEYFIALLWKFLKAGYVEDWKFHNTYSGTPQGSIISPILSNIYLNELDRFMELYMKQFQS  240
            DE FI+L+WKFLKAGY+E+W+++ TYSG PQGS ISPI +NIYL+ELD +M+ Y  +++ 
Sbjct  181  DEAFIGLIWKFLKAGYMEQWQYNCTYSGVPQGSGISPICANIYLSELDNYMQEYKEKYDC  240

Query  241  GKKRQKSEEYASWEHKLKYLRYSKYTKGKWADLTVEKRKTA-NESIQVIRNEMLKCDYSD  299
               R+++     +  +       +Y K++ A +  EK        ++  R   ++ +Y +
Sbjct  241  EPERRRTTREYERASR-------RYRKARKALMGAEKSTPELVKEFKDSRRKKMNQHYYN  293

Query  300  PQDSGYRRLFYVRYADDWLCGVTGSKQDAEEIKADIQRFlsetlklelseektlITNARD  359
            P + G++++ Y RYADD + GV GSK+DAE IK D++ FL E L LE+SEEKT +T++  
Sbjct  294  PFEEGFKKIQYNRYADDFVIGVIGSKKDAEKIKEDVKIFLQEKLHLEMSEEKTKVTHSSK  353

Query  360  TARFLSYDIFVADNDNLREDKNGYTRRVHNGKVKLYVPREKWQKKLTDYQALEIK--YQN  417
              R+L+YD+ V ++ N++  KNG  +RV  GKV LY+P+EKW KK  +  A+++K   + 
Sbjct  354  PVRYLGYDFKVIHSKNMKRCKNGDMKRVWYGKVFLYMPKEKWIKKAMERGAIQVKRNNDT  413

Query  418  GKEIFVPVHRTYLINNDDLEILQQYNAEIRGLYNYYKIADNVSVLGHFNYVMKFSMFKTF  477
            GKE+  P+ R  L+N  D EI+  +N+EIRGLYN+Y+IA+NV+ L  + Y++++SM+KT+
Sbjct  414  GKEMWRPMPRKDLMNRSDAEIVSTFNSEIRGLYNFYRIAENVGALHKYYYMVRYSMLKTL  473

Query  478  GAKYKLHISGVRKKYGYKR-FGVRYQTKQGEKTLYFYEDGFKKVKNAVASPEVDSVPKVY  536
            ++K + ++S ++K+   +  + + Y+T +G K   FY+DGF+  K++ +  +V  V   Y
Sbjct  474  AGKHRTNVSVIKKRHMVNGVLRIPYDTTKGRKYCEFYHDGFR--KHSDGYDNVADVMPSY  531

Query  537  RN-NNPTSLISRLRAKHCEWCGATNVKLEIHHVkklkdlkgkkRWERLMIARKRKTLALC  595
            R+ ++  ++++R++A  CE CG     L +HHV+ LK LKG+   E+ M+  +RK+LALC
Sbjct  532  RKYDSRHTIVNRIKAGVCEICGEHADYLCMHHVRTLKSLKGRDIFEQKMLKMRRKSLALC  591

Query  596  VQCHDSLHAGK  606
             +C + LH  K
Sbjct  592  PDCFELLHETK  602

17) Alfi_2157 in NC_018011


> NC_021994_R1|7|G7|529233401|YP_008394213.1|Enterococcus_faecium_Aus0085|+|4653..6470|-|EFAU085_00689|HNH 
endonuclease domain 
protein
Length=605

 Score =  429 bits (1616),  Expect = 2e-121, Method: Compositional matrix adjust.
 Identities = 277/604 (46%), Positives = 413/604 (69%), Gaps = 6/604 (0%)

Query  1    MRSPERVLNSLNEHSKDSSYKFERLYRILFNEELFYVAYQKIASNGGSTTKGSDGRSIDE  60
            MR+P +VL+SL+E +  S+YK+ERLYR L+N E++ +AY +IA + GS T+G DG+++D+
Sbjct  1    MRNPIHVLKSLEEKASVSNYKYERLYRNLYNPEFYLLAYANIAKSQGSMTQGVDGQTLDN  60

Query  61   MSLARIETLIASLKDESYQPHPSRRVHIPKKNGKTRPLGIPAFEDKLVQEVVRMILEAIY  120
            MSL+RI+ +I S+++ +YQP P++R  IPKKNGK RPLGI + +DKLVQEVVRMILEAIY
Sbjct  61   MSLPRINRIIESIRNRTYQPKPAKRKYIPKKNGKLRPLGITSTDDKLVQEVVRMILEAIY  120

Query  121  EGHFETTSHGFRPKRSCHTALLHIQKTFSGAKWFIEGDIKGFFDNIDHDVLVGILRERIS  180
            E  F   SHGFRPKRSCHTAL +++K F+G  W++EGDIK+ FDN+DH+VLV +LR RIS
Sbjct  121  EPTFSNNSHGFRPKRSCHTALTQVKKNFTGVTWIVEGDIKACFDNFDHHVLVELLRKRIS  180

Query  181  DDRFIRLIRKFLKAGYVEDWTFHNTYSGMPQGGIVSPILANIYLDKLDKYVKEYIRHFDM  240
            D+ FI LI+KFLKAGY+E+W ++ TYSG+PQG+ +SPI ANIYL  LD+Y++EY   +D 
Sbjct  181  DEAFIGLIWKFLKAGYMEQWQYNCTYSGVPQGSGISPICANIYLSELDNYMQEYKEKYDC  240

Query  241  GTKRRPGKESNDLANERKRTVRKLKKIKDGTEKAALVARLKAIEQERAAFPSGDEMDGSY  300
               RR      + A+ R R  RK   +      + LV  +K   + +      +  + ++
Sbjct  241  EPERRRTTREYERASRRYRKARK-ALMGAEKSTPELVKEFKDSRRKKMNQHYYNPFEEGF  299

Query  301  RRLKYIRYADDFILGVIGSKEDALRIKEDIKsflseslalelseeKTLITHTGKSAKFLG  360
            ++++Y RYADDF++GVIGSK DA +IKED+K FL E L LE+SEEKT +TH++K+ ++LG
Sbjct  300  KKIQYNRYADDFVIGVIGSKKDAEKIKEDVKIFLQEKLHLEMSEEKTKVTHSSKPVRYLG  359

Query  361  YEITVTRNNHQRRDVQGRLRRT-YGKRVRLNVSMATLRDKLLEYGAMEIKLRN--GKEIW  417
            Y++ V ++++ +R  +G ++R  YGK V L ++      K +E GA+++K  N  GKE+W
Sbjct  360  YDFKVIHSKNMKRCKNGDMKRVWYGK-VFLYMPKEKWIKKAMERGAIQVKRNNDTGKEMW  418

Query  418  KPKCRSGLIFNDDLEILDRYNRETVGFCNYYLIANNCVVLHNFRYIMEYSMYKTFAGKYR  477
            +P  R +L+   D EI+  +N E  G+ N+Y IA+N   LH++ Y++ YSM KT+AGK R
Sbjct  419  RPMPRKDLMNRSDAEIVSTFNSEIRGLYNFYRIAENVGALHKYYYMVRYSMLKTLAGKHR  478

Query  478  STVRKINKKYRLNKLFTVKYEQKGVIKSRTFYKTSFKRRTTAFNGSCDIEPYSIADVSRT  537
            + V  I+K+  +N ++ + Y+     K   FY  +F++++ +++   D+ P      SR 
Sbjct  479  TNVSVIKKRHMVNGVLRIPYDTTKGRKYCEFYHDGFRKHSDGYDNVADVMPSYRKYDSRH  538

Query  538  NLTDRLKAEKCELCGATGK-LIMHHVRNLKDLKGKESWKRLMSARKRKTIALCPSCHRLR  596
             + +R+KA  CE+CG  +  L MHHVR LK LKG++   + M   +RK++ALCP C  L 
Sbjct  539  TIVNRIKAGVCEICGEHADYLCMHHVRTLKSLKGRDIFEQKMLKMRRKSLALCPDCFELL  598

Query  597  HLGK  600
            H  K
Sbjct  599  HETK  602

18) AL1_29310 in NC_021030


> NC_021994_R1|7|G7|529233401|YP_008394213.1|Enterococcus_faecium_Aus0085|+|4653..6470|-|EFAU085_00689|HNH 
endonuclease domain 
protein
Length=605

 Score =  429 bits (1615),  Expect = 3e-121, Method: Compositional matrix adjust.
 Identities = 276/604 (46%), Positives = 412/604 (69%), Gaps = 6/604 (0%)

Query  8    MRSPERVLNSLNEHSKDSSYKFERLYRILFNEELFYVAYQKIASNGGSTTKGSDGRSIDE  67
            MR+P +VL+SL+E +  S+YK+ERLYR L+N E++ +AY +IA + GS T+G DG+++D+
Sbjct  1    MRNPIHVLKSLEEKASVSNYKYERLYRNLYNPEFYLLAYANIAKSQGSMTQGVDGQTLDN  60

Query  68   MSLARIETLIASLKDESYQPHPSRRVHIPKKNGKTRPLGIPAFEDKLVQEVVRMILEAIY  127
            MSL+RI+ +I S+++ +YQP P++R  IPKKNGK RPLGI + +DKLVQEVVRMILEAIY
Sbjct  61   MSLPRINRIIESIRNRTYQPKPAKRKYIPKKNGKLRPLGITSTDDKLVQEVVRMILEAIY  120

Query  128  EGHFETTSHGFRPKRSCHTALLHIQKTFSGAKWFIEGDIKGFFDNIDHDVLVGILRERIS  187
            E  F   SHGFRPKRSCHTAL +++K F+G  W++EGDIK+ FDN+DH+VLV +LR RIS
Sbjct  121  EPTFSNNSHGFRPKRSCHTALTQVKKNFTGVTWIVEGDIKACFDNFDHHVLVELLRKRIS  180

Query  188  DDRFIRLIRKFLKAGYVEDWTFHNTYSGMPQGGIVSPILANIYLDKLDKYVKEYIRHFDM  247
            D+ FI LI+KFLKAGY+E+W ++ TYSG+PQG+ +SPI ANIYL  LD+Y++EY   +D 
Sbjct  181  DEAFIGLIWKFLKAGYMEQWQYNCTYSGVPQGSGISPICANIYLSELDNYMQEYKEKYDC  240

Query  248  GTKRRPGKESNDLANERKRTVRKLKKIKDGTEKAALVARLKAIEQERAAFPSGDEMDGSY  307
               RR      + A+ R R  RK   +      + LV  +K   + +      +  + ++
Sbjct  241  EPERRRTTREYERASRRYRKARK-ALMGAEKSTPELVKEFKDSRRKKMNQHYYNPFEEGF  299

Query  308  RRLKYIRYADDFILGVIGSKEDALRIKEDIKsflseslalelseeKTLITHTGKSAKFLG  367
            ++++Y RYADDF++GVIGSK DA +IKED+K FL E L LE+SEEKT +TH++K+ ++LG
Sbjct  300  KKIQYNRYADDFVIGVIGSKKDAEKIKEDVKIFLQEKLHLEMSEEKTKVTHSSKPVRYLG  359

Query  368  YEITVTRNNHQRRDVQGRLRRT-YGKRVRLNVSMATLRDKLLEYGAMEIKLRN--GKEIW  424
            Y++ V ++++ +R  +G ++R  YGK V L ++      K +E GA+++K  N  GKE+W
Sbjct  360  YDFKVIHSKNMKRCKNGDMKRVWYGK-VFLYMPKEKWIKKAMERGAIQVKRNNDTGKEMW  418

Query  425  KPKCRSGLIFNDDLEILDRYNRETVGFCNYYLIANNCVVLHNFRYIMEYSMYKTFAGKYR  484
            +P  R +L+   D EI+  +N E  G+ N+Y IA+N   LH++ Y++ YSM KT+AGK R
Sbjct  419  RPMPRKDLMNRSDAEIVSTFNSEIRGLYNFYRIAENVGALHKYYYMVRYSMLKTLAGKHR  478

Query  485  STVRKINKKYRLNKLFTVKYEQKGVIKSRTFYKTSFKRRTTAFNGSCDIEPYSIADASRT  544
            + V  I+K+  +N ++ + Y+     K   FY  +F++++ +++   D+ P      SR 
Sbjct  479  TNVSVIKKRHMVNGVLRIPYDTTKGRKYCEFYHDGFRKHSDGYDNVADVMPSYRKYDSRH  538

Query  545  NLTDRLKAEKCELCGATGK-LIMHHVRNLKDLKEKESWKRLMSARKRKTIALCPSCHRLR  603
             + +R+KA  CE+CG  +  L MHHVR LK LK ++   + M   +RK++ALCP C  L 
Sbjct  539  TIVNRIKAGVCEICGEHADYLCMHHVRTLKSLKGRDIFEQKMLKMRRKSLALCPDCFELL  598

Query  604  HLGK  607
            H  K
Sbjct  599  HETK  602

19) Alfi_0692 in NC_018011


> NC_021994_R1|7|G7|529233401|YP_008394213.1|Enterococcus_faecium_Aus0085|+|4653..6470|-|EFAU085_00689|HNH 
endonuclease domain 
protein
Length=605

 Score =  422 bits (1588),  Expect = 4e-119, Method: Compositional matrix adjust.
 Identities = 277/604 (46%), Positives = 414/604 (69%), Gaps = 6/604 (0%)

Query  1    MRSPERVLNSLNEHSKDSSYKFERLYRILFNEELFYVAYQKIASNGGSTTKGSDGRSIDE  60
            MR+P +VL+SL+E +  S+YK+ERLYR L+N E++ +AY +IA + GS T+G DG+++D+
Sbjct  1    MRNPIHVLKSLEEKASVSNYKYERLYRNLYNPEFYLLAYANIAKSQGSMTQGVDGQTLDN  60

Query  61   MSLARIETLIASLKDESYQPHPSRRVHIPKKNGKTRPLGIPAFEDKLVQEVVRMILEAIY  120
            MSL+RI+ +I S+++ +YQP P++R  IPKKNGK RPLGI + +DKLVQEVVRMILEAIY
Sbjct  61   MSLPRINRIIESIRNRTYQPKPAKRKYIPKKNGKLRPLGITSTDDKLVQEVVRMILEAIY  120

Query  121  EGHFETTSHGFRPKRSCHTALLHIQKTFSGAKWFIEGDIKGFFDNIDHDVLVGILRERIS  180
            E  F   SHGFRPKRSCHTAL +++K F+G  W++EGDIK+ FDN+DH+VLV +LR RIS
Sbjct  121  EPTFSNNSHGFRPKRSCHTALTQVKKNFTGVTWIVEGDIKACFDNFDHHVLVELLRKRIS  180

Query  181  DDRFIRLIRKFLKAGYVEDWTFHNTYSGMPQGGIVSPILANIYLDKLDKYVKEYIRHFDM  240
            D+ FI LI+KFLKAGY+E+W ++ TYSG+PQG+ +SPI ANIYL  LD+Y++EY   +D 
Sbjct  181  DEAFIGLIWKFLKAGYMEQWQYNCTYSGVPQGSGISPICANIYLSELDNYMQEYKEKYDC  240

Query  241  GTKRRPGKESNDLANErkrtvrklkkvkDGTEKAALVARLKAIEQERAAFPSGDEMDGSY  300
               RR      + A+ R R  RK     + +  + LV  +K   + +      +  + ++
Sbjct  241  EPERRRTTREYERASRRYRKARKALMGAEKST-PELVKEFKDSRRKKMNQHYYNPFEEGF  299

Query  301  RRLKYIRYADDFILGVIGSKEDALRIKEDIKsflseslalelseeKTLITHTGKSAKFLG  360
            ++++Y RYADDF++GVIGSK DA +IKED+K FL E L LE+SEEKT +TH++K+ ++LG
Sbjct  300  KKIQYNRYADDFVIGVIGSKKDAEKIKEDVKIFLQEKLHLEMSEEKTKVTHSSKPVRYLG  359

Query  361  YEITVTRNNHQRRDVQGRLRRT-YGKRVRLNVSMATLRDKLLEYGAMEIKLRN--GKEIW  417
            Y++ V ++++ +R  +G ++R  YGK V L ++      K +E GA+++K  N  GKE+W
Sbjct  360  YDFKVIHSKNMKRCKNGDMKRVWYGK-VFLYMPKEKWIKKAMERGAIQVKRNNDTGKEMW  418

Query  418  KPKCRSGLIFNDDLEILDRYNRETVGFCNYYLIANNCVVLHNFRYIMEYSMYKTFAGKYR  477
            +P  R +L+   D EI+  +N E  G+ N+Y IA+N   LH++ Y++ YSM KT+AGK R
Sbjct  419  RPMPRKDLMNRSDAEIVSTFNSEIRGLYNFYRIAENVGALHKYYYMVRYSMLKTLAGKHR  478

Query  478  STVRKINKKYRLNKLFTVKYEQKGVIKSRTFYKTSFKRRTTAFNGSCDIEPYSIADVSRT  537
            + V  I+K+  +N ++ + Y+     K   FY  +F++++ +++   D+ P      SR 
Sbjct  479  TNVSVIKKRHMVNGVLRIPYDTTKGRKYCEFYHDGFRKHSDGYDNVADVMPSYRKYDSRH  538

Query  538  NLTDRLKAEKCELCGATGK-LIMHHVRNLKDLKGKESWKRLMSARKRKTIALCPSCHRLR  596
             + +R+KA  CE+CG  +  L MHHVR LK LKG++   + M   +RK++ALCP C  L 
Sbjct  539  TIVNRIKAGVCEICGEHADYLCMHHVRTLKSLKGRDIFEQKMLKMRRKSLALCPDCFELL  598

Query  597  HLGK  600
            H  K
Sbjct  599  HETK  602

20) Alfi_2107 in NC_018011


> NC_021994_R1|7|G7|529233401|YP_008394213.1|Enterococcus_faecium_Aus0085|+|4653..6470|-|EFAU085_00689|HNH 
endonuclease domain 
protein
Length=605

 Score =  422 bits (1588),  Expect = 4e-119, Method: Compositional matrix adjust.
 Identities = 277/604 (46%), Positives = 414/604 (69%), Gaps = 6/604 (0%)

Query  1    MRSPERVLNSLNEHSKDSSYKFERLYRILFNEELFYVAYQKIASNGGSTTKGSDGRSIDE  60
            MR+P +VL+SL+E +  S+YK+ERLYR L+N E++ +AY +IA + GS T+G DG+++D+
Sbjct  1    MRNPIHVLKSLEEKASVSNYKYERLYRNLYNPEFYLLAYANIAKSQGSMTQGVDGQTLDN  60

Query  61   MSLARIETLIASLKDESYQPHPSRRVHIPKKNGKTRPLGIPAFEDKLVQEVVRMILEAIY  120
            MSL+RI+ +I S+++ +YQP P++R  IPKKNGK RPLGI + +DKLVQEVVRMILEAIY
Sbjct  61   MSLPRINRIIESIRNRTYQPKPAKRKYIPKKNGKLRPLGITSTDDKLVQEVVRMILEAIY  120

Query  121  EGHFETTSHGFRPKRSCHTALLHIQKTFSGAKWFIEGDIKGFFDNIDHDVLVGILRERIS  180
            E  F   SHGFRPKRSCHTAL +++K F+G  W++EGDIK+ FDN+DH+VLV +LR RIS
Sbjct  121  EPTFSNNSHGFRPKRSCHTALTQVKKNFTGVTWIVEGDIKACFDNFDHHVLVELLRKRIS  180

Query  181  DDRFIRLIRKFLKAGYVEDWTFHNTYSGMPQGGIVSPILANIYLDKLDKYVKEYIRHFDM  240
            D+ FI LI+KFLKAGY+E+W ++ TYSG+PQG+ +SPI ANIYL  LD+Y++EY   +D 
Sbjct  181  DEAFIGLIWKFLKAGYMEQWQYNCTYSGVPQGSGISPICANIYLSELDNYMQEYKEKYDC  240

Query  241  GTKRRPGKESNDLANErkrtvrklkkvkDGTEKAALVARLKAIEQERAAFPSGDEMDGSY  300
               RR      + A+ R R  RK     + +  + LV  +K   + +      +  + ++
Sbjct  241  EPERRRTTREYERASRRYRKARKALMGAEKST-PELVKEFKDSRRKKMNQHYYNPFEEGF  299

Query  301  RRLKYIRYADDFILGVIGSKEDALRIKEDIKsflseslalelseeKTLITHTGKSAKFLG  360
            ++++Y RYADDF++GVIGSK DA +IKED+K FL E L LE+SEEKT +TH++K+ ++LG
Sbjct  300  KKIQYNRYADDFVIGVIGSKKDAEKIKEDVKIFLQEKLHLEMSEEKTKVTHSSKPVRYLG  359

Query  361  YEITVTRNNHQRRDVQGRLRRT-YGKRVRLNVSMATLRDKLLEYGAMEIKLRN--GKEIW  417
            Y++ V ++++ +R  +G ++R  YGK V L ++      K +E GA+++K  N  GKE+W
Sbjct  360  YDFKVIHSKNMKRCKNGDMKRVWYGK-VFLYMPKEKWIKKAMERGAIQVKRNNDTGKEMW  418

Query  418  KPKCRSGLIFNDDLEILDRYNRETVGFCNYYLIANNCVVLHNFRYIMEYSMYKTFAGKYR  477
            +P  R +L+   D EI+  +N E  G+ N+Y IA+N   LH++ Y++ YSM KT+AGK R
Sbjct  419  RPMPRKDLMNRSDAEIVSTFNSEIRGLYNFYRIAENVGALHKYYYMVRYSMLKTLAGKHR  478

Query  478  STVRKINKKYRLNKLFTVKYEQKGVIKSRTFYKTSFKRRTTAFNGSCDIEPYSIADVSRT  537
            + V  I+K+  +N ++ + Y+     K   FY  +F++++ +++   D+ P      SR 
Sbjct  479  TNVSVIKKRHMVNGVLRIPYDTTKGRKYCEFYHDGFRKHSDGYDNVADVMPSYRKYDSRH  538

Query  538  NLTDRLKAEKCELCGATGK-LIMHHVRNLKDLKGKESWKRLMSARKRKTIALCPSCHRLR  596
             + +R+KA  CE+CG  +  L MHHVR LK LKG++   + M   +RK++ALCP C  L 
Sbjct  539  TIVNRIKAGVCEICGEHADYLCMHHVRTLKSLKGRDIFEQKMLKMRRKSLALCPDCFELL  598

Query  597  HLGK  600
            H  K
Sbjct  599  HETK  602

21) SPN23F_12790 in NC_011900


> NC_021994_R1|7|G7|529233401|YP_008394213.1|Enterococcus_faecium_Aus0085|+|4653..6470|-|EFAU085_00689|HNH 
endonuclease domain 
protein
Length=605

 Score =  422 bits (1587),  Expect = 4e-119, Method: Compositional matrix adjust.
 Identities = 267/605 (45%), Positives = 417/605 (69%), Gaps = 7/605 (1%)

Query  1    MRNPQNVLNNLTKHSKDKNYQFERLYRLLYNKEMYLVAYQTIYANPGHLTPGVDELTIDG  60
            MRNP +VL++L   +   NY++ERLYR LYN E YL+AY  I  + G +T GVD  T+D 
Sbjct  1    MRNPIHVLKSLEEKASVSNYKYERLYRNLYNPEFYLLAYANIAKSQGSMTQGVDGQTLDN  60

Query  61   MSIARIDQLIDSLKDESYQPHPSRRTYIPKKNGKLRPLGIPSFDDKLLQQVIKMILEAIY  120
            MS++RI+++I+S+++ +YQP P++R YIPKKNGKLRPLGI S DDKL+Q+V++MILEAIY
Sbjct  61   MSLPRINRIIESIRNRTYQPKPAKRKYIPKKNGKLRPLGITSTDDKLVQEVVRMILEAIY  120

Query  121  EGQFEPSSHGFRPNKSCHTALTQIQKTYTGTKWFIEGDIKSFFDNINHDVMIHILRERIT  180
            E  F  +SHGFRP++SCHTALTQ++K +TG  W++EGDIK+ FDN++H+V++++LR RI+
Sbjct  121  EPTFSNNSHGFRPKRSCHTALTQVKKNFTGVTWIVEGDIKACFDNFDHHVLVELLRKRIS  180

Query  181  DERFLRLIRKFLNAGYVEDWKFYKTYSGTPQGGIISPILANIYLDKFDKYMTDYVKNF-C  239
            DE F+ LI+KFL+AGY+E+W++  TYSG PQG+ ISPI ANIYL  +D+YM +Y  ++ C
Sbjct  181  DEAFIGLIWKFLKAGYMEQWQYNCTYSGVPQGSGISPICANIYLSELDNYMQEYKEKYDC  240

Query  240  QGKYRKRTPEYRQNEIALGKARRALECVSTENQRQEVIQRIRQLEKERVLIPHSDPMDSS  299
            +   R+ T EY +      KAR+AL  +++E+   E+++ +++  + ++     +P + +
Sbjct  241  EPERRRTTREYERASRRYRKARKAL--MGAEKSTPELVKEFKDSRRKKMNQHYYNPFEEG  298

Query  300  FKRLTYTRYADDFICGVIGSKEDAHRIKADIKDYLEAVLKLELSVEKTLITNARDKAKFL  359
            FK++ Y RYADDF+ GVIGSK DA++IK D+K +L+  L LE+S EKT +T++    ++L
Sbjct  299  FKKIQYNRYADDFVIGVIGSKKDAEKIKEDVKIFLQEKLHLEMSEEKTKVTHSSKPVRYL  358

Query  360  GYHLYIRQSNLAKRDSAGRLVRNYTGRLVLEVSIETIRDRLLSYGAM--KMTYHRGYEVW  417
            GY++ + +S+  KR   G + R   G++ L ++ E    + +  GA+  K   + G E+W
Sbjct  359  GYDFKVIHSKNMKRCKNGDMKRVWYGKVFLYMPKEKWIKKAMERGAIQVKRNNDTGKEMW  418

Query  418  KPTARYFMKDCDDLEILERYNAEIRGFYNYYCIANNSSILHRFKYIMEYSMyktyatkyr  477
            +P +R  + +  D EI+  +N+EIRG+YN+Y IA+N + LH++ Y++ YSM KT A K R
Sbjct  419  RPMPRKDLMNRSDAEIVSTFNSEIRGLYNFYRIAENVGALHKYYYMVRYSMLKTLAGKHR  478

Query  478  ttkSHIIRKYKKDGQFSVQYIGRKGDTMTRYLYNGGFKRQKKSFLE-NDNLPNTAKYFSR  536
            T  S I ++   +G + + Y   KG     + Y++GF+++  ++ +  D +P+  KY SR
Sbjct  479  TNVSVIKKRHMVNGVLRIPYDTTKGRKYCEF-YHDGFRKHSDGYDNVADVMPSYRKYDSR  537

Query  537  TNLIDRLKASRCEYCQATDSSLEIHHVRKLKDLKGKTFWERLMISRQRKTIALCKDCHKK  596
              +++R+KA+ CE C      L +HHVR LK LKG+ + E+ M+  +RK++ALC DC   
Sbjct  538  HTIVNRIKAGVCEICGEHADYLCMHHVRTLKSLKGRDIFEQKMLKMRRKSLALCPDCFEL  597

Query  597  LHHGK  601
            LH+ K
Sbjct  598  LHETK  602

22) BCQ_2135 in NC_011969


> NC_021994_R1|7|G7|529233401|YP_008394213.1|Enterococcus_faecium_Aus0085|+|4653..6470|-|EFAU085_00689|HNH 
endonuclease domain 
protein
Length=605

 Score =  422 bits (1587),  Expect = 5e-119, Method: Compositional matrix adjust.
 Identities = 265/610 (44%), Positives = 411/610 (68%), Gaps = 17/610 (2%)

Query  5    MREPRMILDALTKNAVKENYIFTRLYRNLYNKKFFLDAYGNIYHKPGNMTQGTDKETIDG  64
            MR+P  +L +L  +A   NY + RLYRNLYN  F+L AY+NI    G+MTQG D +T+D 
Sbjct  1    MRNPIHVLKSLEEKASVSNYKYERLYRNLYNPEFYLLAYANIAKSQGSMTQGVDGQTLDN  60

Query  65   FSMDWIENIISSLKDESYKPNPSRRVYIPKKDDKQRPLGIPSIKDKIIQEVVKEILVSMY  124
             S+ +I+ II S+++ +Y+P+P++R YIPKK++K RPLGI S  DK++QEVV+ IL ++Y
Sbjct  61   MSLPRINRIIESIRNRTYQPKPAKRKYIPKKNGKLRPLGITSTDDKLVQEVVRMILEAIY  120

Query  125  EPIFSKASHGFRPNKSCHSALNDIKMTFGGIKWWIEGDIKGFFDNIDHHVLIGILRKRIK  184
            EP FS+ SHGFRP++SCH+AL ++K  F G+ W +EGDIK+ FDN+DHHVL+ +LRKRI 
Sbjct  121  EPTFSNNSHGFRPKRSCHTALTQVKKNFTGVTWIVEGDIKACFDNFDHHVLVELLRKRIS  180

Query  185  DEKFIKLIWKFLKAGYMEDWKFNKTFSGTPQGGIISPVLANIYLHELDAFMEKQIIKFDE  244
            DE FI LIWKFLKAGYME+W++N T+SG PQG+ ISP+ ANIYL ELD +M+    K+D 
Sbjct  181  DEAFIGLIWKFLKAGYMEQWQYNCTYSGVPQGSGISPICANIYLSELDNYMQEYKEKYDC  240

Query  245  GKRRRDNPVYKKYNTAIWYRKNKLKEKWNTLNDDERK--ELQSEISTLEKEREKHSAVDN  302
               RR         ++ +YRK +     ++L + E+   EL  E+    + + ++   + 
Sbjct  241  EPERRRTTR-EYERASRRYRKAR-----KALMGAEKSTPELVKEFKDSRRKKMNQHYYNP  294

Query  303  MDASFKRLKYVRYADDFVVGVIGSKEDSKRIKEEITEFLHTSLKLELSQEKTLITSNKNL  362
             + +FK+++Y RYADDFV+GVIGSK D+ +IKE++  FL+  L LE+S+EKT +T + + 
Sbjct  295  FEEGFKKIQYNRYADDFVIGVIGSKKDAEKIKEDVKIFLQEKLHLEMSEEKTKVTHSSKP  354

Query  363  IKFLGYEIGIDGGHDSKTNTNGIKKRHLSGKPMLYLPYNN-MRNFLLKNDYMKIEGND--  419
            +++LGY++ +  + + K   NG  KR   GK  LY+P ++ +++ + +        ND  
Sbjct  355  VRYLGYDFKVIHSKNMKRCKNGDMKRVWYGKVFLYMPKEKWIKKAMERGAIQVKRNNDTG  414

Query  420  ---WKPVHRRYLVNQDDIEILSTYNAEIRGFYEYYKMAINVYKLNGAFHIIKTSFAKTMA  476
               W+P+ R+ L+N+ D EI+ST+N+EIRG+Y++Y++A NV  L+  + +++ S  KT+A
Sbjct  415  KEMWRPMPRKDLMNRSDAEIVSTFNSEIRGLYNFYRIAENVGALHKYYYMVRYSMLKTLA  474

Query  477  NKYKLSVNRVFRKYSVNGVLGVFYDTKNGKKFRPFYNDGFKMDKQ-YSKSLSIDTLPNTN  535
             K + +V+ + ++  VNGVL + YDT +G+K+  FY+DGF+ + + Y +    D +P+  
Sbjct  475  GKHRTNVSVIKKRHMVNGVLRIPYDTTKGRKYCEFYHDGFRKHSDGYDN--VADVMPSYR  532

Query  536  IYSGRTSLVSRLLASKCEFCGTTEGKFEVHHVRklkdlkgkkkWEQKMIARNRKTMVLCI  595
             Y +R ++V+R+ A+ CE+CG   + + +HHVR LK LKG+   EQKM+   RK++ LC 
Sbjct  533  KYDSRHTIVNRIKAGVCEICGEHADYLCMHHVRTLKSLKGRDIFEQKMLKMRRKSLALCP  592

Query  596  NCHVDLHRGK  605
            +C   LH  K
Sbjct  593  DCFELLHETK  602

23) Alfi_0686 in NC_018011


> NC_021994_R1|7|G7|529233401|YP_008394213.1|Enterococcus_faecium_Aus0085|+|4653..6470|-|EFAU085_00689|HNH 
endonuclease domain 
protein
Length=605

 Score =  420 bits (1580),  Expect = 2e-118, Method: Compositional matrix adjust.
 Identities = 270/606 (45%), Positives = 421/606 (70%), Gaps = 9/606 (1%)

Query  1    MRNPERVLNSLSEHSKVSSYKFERLYRVLFNSEMFLLAYHNIQGRQGNMTEGSDGKTIDG  60
            MRNP +VL+SL E + VS+YK+ERLYR L+N+E +LLAY NI   QG+MT+G DG+T+D 
Sbjct  1    MRNPIHVLKSLEEKASVSNYKYERLYRNLYNPEFYLLAYANIAKSQGSMTQGVDGQTLDN  60

Query  61   MSLKRIENLIDALKDESYQPKPARRTYIPKKNGNMRPLGIPSIDDKLVQEVLRMLLEAIY  120
            MSL RI+ +I+++++ +YQPKPA+R YIPKKNG++RPLGI S DDKLVQEV+RM+LEAIY
Sbjct  61   MSLPRINRIIESIRNRTYQPKPAKRKYIPKKNGKLRPLGITSTDDKLVQEVVRMILEAIY  120

Query  121  EGSFENTSHGFRPKRSCHTALIQVQKNFTAAKWFIEGDIEGFFDNINHDVLIGILKERIA  180
            E +F N SHGFRPKRSCHTAL QV+KNFT+  W++EGDI + FDN++H+VL+ +L+ RI+
Sbjct  121  EPTFSNNSHGFRPKRSCHTALTQVKKNFTGVTWIVEGDIKACFDNFDHHVLVELLRKRIS  180

Query  181  DDRFIRLMWKFLKAGYIEDWTFHRTYSGTPQGGIISPILANIYLDKLDKYMKEYACQFDR  240
            D+ FI L+WKFLKAGY+E+W ++ TYSG PQG+ ISPI ANIYL  LD+YM+EY  ++D 
Sbjct  181  DEAFIGLIWKFLKAGYMEQWQYNCTYSGVPQGSGISPICANIYLSELDNYMQEYKEKYDC  240

Query  241  GDRRAMNLEYKRYSRKIWWLGTKLKQTKDKDTRKELIDAIKQHQKNRMHLPSVDEMDEGY  300
               R         + +  + + K     +K T  EL+  +K+ ++++M+    +  +EG+
Sbjct  241  EPERRRTTREYERASRRYRKARKALMGAEKSTP-ELVKEFKDSRRKKMNQHYYNPFEEGF  299

Query  301  RRIKYVRYADDFIIGVIGSKSDCEAIKEDIKNFlgeklkltlseektlitHGNRKAKFLG  360
            ++I+Y RYADDF+IGVIGSK D E IKED+K FL EKL L +SEEKT +TH+++  ++LG
Sbjct  300  KKIQYNRYADDFVIGVIGSKKDAEKIKEDVKIFLQEKLHLEMSEEKTKVTHSSKPVRYLG  359

Query  361  YEIYVRPFTDKTLRGEKSGVLIKA-YGKKVVLEVPMSTMRDKLLYYEAMEIHQFE--GKA  417
            Y++  + +  K ++  K+G + +  YG KV L +P      K +   A+++ + +  GK 
Sbjct  360  YDF--KVIHSKNMKRCKNGDMKRVWYG-KVFLYMPKEKWIKKAMERGAIQVKRNNDTGKE  416

Query  418  KWKPTSRTKLLHLDDLEILDAYNREIRGFANYFSIANNSSHLNSFKYIMQYSLYKTFARK  477
             W+P +R  L++  D EI+ ++N EIRG+ N++ IA+N + L+ + Y+++YS+ KT+A K
Sbjct  417  MWRPMPRKDLMNRSDAEIVSTFNSEIRGLYNFYRIAENVGALHKYYYMVRYSMLKTLAGK  476

Query  478  YSTTARKIIAKYRHHKDFAVFYEDKKGGKKMRVFFNGSFKRKTTAMDASCDYVANTIFNT  537
              T    I  +   +  + + Y+  K G+K   F++++F++ + + D   D +++     
Sbjct  477  HRTNVSVIKKRHMVNGVLRIPYDTTK-GRKYCEFYHDGFRKHSDGYDNVADVMPSYRKYD  535

Query  538  TVSSLIQRLKAGKCELCGA-TENIEIHHVKRLKDLKGKEPWKIQMIGRQRKTLAVCIPCH  596
            +  ++++R+KAG CE+CG  ++ + +HHV+ LK LKG++    +M+  +RK+LA+C  C 
Sbjct  536  SRHTIVNRIKAGVCEICGEHADYLCMHHVRTLKSLKGRDIFEQKMLKMRRKSLALCPDCF  595

Query  597  NKIHHG  602
            + +H+ 
Sbjct  596  ELLHET  601

24) Alfi_0997 in NC_018011


> NC_021994_R1|7|G7|529233401|YP_008394213.1|Enterococcus_faecium_Aus0085|+|4653..6470|-|EFAU085_00689|HNH 
endonuclease domain 
protein
Length=605

 Score =  420 bits (1580),  Expect = 2e-118, Method: Compositional matrix adjust.
 Identities = 270/606 (45%), Positives = 421/606 (70%), Gaps = 9/606 (1%)

Query  1    MRNPERVLNSLSEHSKVSSYKFERLYRVLFNSEMFLLAYHNIQGRQGNMTEGSDGKTIDG  60
            MRNP +VL+SL E + VS+YK+ERLYR L+N+E +LLAY NI   QG+MT+G DG+T+D 
Sbjct  1    MRNPIHVLKSLEEKASVSNYKYERLYRNLYNPEFYLLAYANIAKSQGSMTQGVDGQTLDN  60

Query  61   MSLKRIENLIDALKDESYQPKPARRTYIPKKNGNMRPLGIPSIDDKLVQEVLRMLLEAIY  120
            MSL RI+ +I+++++ +YQPKPA+R YIPKKNG++RPLGI S DDKLVQEV+RM+LEAIY
Sbjct  61   MSLPRINRIIESIRNRTYQPKPAKRKYIPKKNGKLRPLGITSTDDKLVQEVVRMILEAIY  120

Query  121  EGSFENTSHGFRPKRSCHTALIQVQKNFTAAKWFIEGDIEGFFDNINHDVLIGILKERIA  180
            E +F N SHGFRPKRSCHTAL QV+KNFT+  W++EGDI + FDN++H+VL+ +L+ RI+
Sbjct  121  EPTFSNNSHGFRPKRSCHTALTQVKKNFTGVTWIVEGDIKACFDNFDHHVLVELLRKRIS  180

Query  181  DDRFIRLMWKFLKAGYIEDWTFHRTYSGTPQGGIISPILANIYLDKLDKYMKEYACQFDR  240
            D+ FI L+WKFLKAGY+E+W ++ TYSG PQG+ ISPI ANIYL  LD+YM+EY  ++D 
Sbjct  181  DEAFIGLIWKFLKAGYMEQWQYNCTYSGVPQGSGISPICANIYLSELDNYMQEYKEKYDC  240

Query  241  GDRRAMNLEYKRYSRKIWWLGTKLKQTKDKDTRKELIDAIKQHQKNRMHLPSVDEMDEGY  300
               R         + +  + + K     +K T  EL+  +K+ ++++M+    +  +EG+
Sbjct  241  EPERRRTTREYERASRRYRKARKALMGAEKSTP-ELVKEFKDSRRKKMNQHYYNPFEEGF  299

Query  301  RRIKYVRYADDFIIGVIGSKSDCEAIKEDIKNFlgeklkltlseektlitHGNRKAKFLG  360
            ++I+Y RYADDF+IGVIGSK D E IKED+K FL EKL L +SEEKT +TH+++  ++LG
Sbjct  300  KKIQYNRYADDFVIGVIGSKKDAEKIKEDVKIFLQEKLHLEMSEEKTKVTHSSKPVRYLG  359

Query  361  YEIYVRPFTDKTLRGEKSGVLIKA-YGKKVVLEVPMSTMRDKLLYYEAMEIHQFE--GKA  417
            Y++  + +  K ++  K+G + +  YG KV L +P      K +   A+++ + +  GK 
Sbjct  360  YDF--KVIHSKNMKRCKNGDMKRVWYG-KVFLYMPKEKWIKKAMERGAIQVKRNNDTGKE  416

Query  418  KWKPTSRTKLLHLDDLEILDAYNREIRGFANYFSIANNSSHLNSFKYIMQYSLYKTFARK  477
             W+P +R  L++  D EI+ ++N EIRG+ N++ IA+N + L+ + Y+++YS+ KT+A K
Sbjct  417  MWRPMPRKDLMNRSDAEIVSTFNSEIRGLYNFYRIAENVGALHKYYYMVRYSMLKTLAGK  476

Query  478  YSTTARKIIAKYRHHKDFAVFYEDKKGGKKMRVFFNGSFKRKTTAMDASCDYVANTIFNT  537
              T    I  +   +  + + Y+  K G+K   F++++F++ + + D   D +++     
Sbjct  477  HRTNVSVIKKRHMVNGVLRIPYDTTK-GRKYCEFYHDGFRKHSDGYDNVADVMPSYRKYD  535

Query  538  TVSSLIQRLKAGKCELCGA-TENIEIHHVKRLKDLKGKEPWKIQMIGRQRKTLAVCIPCH  596
            +  ++++R+KAG CE+CG  ++ + +HHV+ LK LKG++    +M+  +RK+LA+C  C 
Sbjct  536  SRHTIVNRIKAGVCEICGEHADYLCMHHVRTLKSLKGRDIFEQKMLKMRRKSLALCPDCF  595

Query  597  NKIHHG  602
            + +H+ 
Sbjct  596  ELLHET  601

25) MGAS10750_Spy1709 in NC_008024


> NC_021994_R1|7|G7|529233401|YP_008394213.1|Enterococcus_faecium_Aus0085|+|4653..6470|-|EFAU085_00689|HNH 
endonuclease domain 
protein
Length=605

 Score =  414 bits (1558),  Expect = 9e-117, Method: Compositional matrix adjust.
 Identities = 274/610 (45%), Positives = 406/610 (67%), Gaps = 11/610 (1%)

Query  21   MRNPNNVLISLRKHSKEENYTYKRLYRNLYNIDLFLQAYQNIYANAGNMTKGVDNQTISA  80
            MRNP +VL SL   +   NY Y RLYRNLYN +++L AY NI  + G+MT+GVD QT+  
Sbjct  1    MRNPIHVLKSLEEKASVSNYKYERLYRNLYNPEFYLLAYANIAKSQGSMTQGVDGQTLDN  60

Query  81   MSLERINKIIDSLKDESYSPTPTKRVYIPKKNGKLRPLGIPSIGDKLVQEVCRMLLNSIY  140
            MSL RIN+II+S+++ +Y P P+KR YIPKKNGKLRPLGI S +DKLVQEV RM+L++IY
Sbjct  61   MSLPRINRIIESIRNRTYQPKPAKRKYIPKKNGKLRPLGITSTDDKLVQEVVRMILEAIY  120

Query  141  DESFEDTSHGFRDNRSCHTALRQIQNRFVRCKWFVEGDIKGFFDNIDHNIMIDILSKRID  200
            + +F + SHGFR +RSCHTAL Q+++ F    W+VEGDIK+ FDN+DH++++++L KRI 
Sbjct  121  EPTFSNNSHGFRPKRSCHTALTQVKKNFTGVTWIVEGDIKACFDNFDHHVLVELLRKRIS  180

Query  201  DERFLRLIRKFLKSGYMEQNQYHNTYSGMPQGSIISPILSNIYLDKFDKYMQNYKESFDK  260
            DE F+ LI+KFLK+GYMEQ QY+ TYSG+PQGS ISPI +NIYL  +D+YMQ+YKE +D 
Sbjct  181  DEAFIGLIWKFLKAGYMEQWQYNCTYSGVPQGSGISPICANIYLSELDNYMQEYKEKYDC  240

Query  261  GNKRKQNKEYKALYDRRKRLENKLSKTTNKTeiddikseieeiNKRYFNIPCLNPMDENF  320
               R++         RR R   K    ++K+  + +K   +   K+  N    NP +E F
Sbjct  241  EPERRRTTREYERASRRYRKARKALMGAEKSTPELVKEFKDSRRKK-MNQHYYNPFEEGF  299

Query  321  KRIQYVRYADDFIIGIIGSKADAEMVKQDIGQFIKSELNLELSDEKTLVTKSTDRAKFLG  380
            K+IQY RYADDF+IG+IGSK DAE +K+D+  F++  L+LE+S+EKT VT S+   ++LG
Sbjct  300  KKIQYNRYADDFVIGVIGSKKDAEKIKEDVKIFLQEKLHLEMSEEKTKVTHSSKPVRYLG  359

Query  381  FDIRVTPGSNHTKRTKAGIKARNFGGHVRLELSTSTIQNKLTELGVLRIKNLN--GKEVW  438
            +D++V   S++ KR K G   R   G V L ++     +K  E G +++K  N  GKE+W
Sbjct  360  YDFKVIH-SKNMKRCKNGDMKRVWYGKVFLYMPKEKWIKKAMERGAIQVKRNNDTGKEMW  418

Query  439  FPKERTKLTSRTDLSILEQYNGEIRGFCNYYRLANNSSKLHKFRYIMEYSMYKTLACKYR  498
             P  R  L +R+D  I+  +N+EIRG+ N+YR+A+N + LHK+ Y++ YSM KTLA K R
Sbjct  419  RPMPRKDLMNRSDAEIVSTFNSEIRGLYNFYRIAENVGALHKYYYMVRYSMLKTLAGKHR  478

Query  499  TKVTDIITRYRTDKDFGISYTDKNGNNKTRLLWKDSLARKEIPQGDNADVIHKQKFYLKK  558
            T+V+ I  R   +  + I+Y   +G +   +   D++ +     ++ ADV+   + Y  +
Sbjct  479  TNVSVIKKRHMVNGVLRIPYDTTKGRKYCEFY-HDGFRKHSDGYDNVADVMPSYRKYDSR  537

Query  559  PTLGLRLKNNKCEWCGKETNNLKVYQVKKLKDLTDEYAWHVF---MKSINRKTLVICNEC  615
             T+  R+K   CE CG +++ L + +V+ LK L    ++++F   M  + RK+L +C +C
Sbjct  538  HTIVNRIKAGVCEICGEHADYLCMHHVRTLKSLK---GRDIFEQKMLKMRRKSLALCPDC  594

Query  616  FEKINNSNEE  625
            FE +++++E 
Sbjct  595  FELLHETKES  604

26) HD73_2733 in NC_020238


> NC_021994_R1|7|G7|529233401|YP_008394213.1|Enterococcus_faecium_Aus0085|+|4653..6470|-|EFAU085_00689|HNH 
endonuclease domain 
protein
Length=605

 Score =  412 bits (1551),  Expect = 3e-116, Method: Compositional matrix adjust.
 Identities = 262/603 (44%), Positives = 407/603 (68%), Gaps = 14/603 (2%)

Query  1    MQCPKIVLSNLRTKSLNKEYQYTRLYRNLYNPDFFLLAYDNLSKNDGALTIGVDQRSIDG  60
            M+ P  VL +L  K+   +Y+Y RLYRNLYNP+F+LLAY N++K++G++T GVD +++D 
Sbjct  1    MRNPIHVLKSLEEKASVSNYKYERLYRNLYNPEFYLLAYANIAKSQGSMTQGVDGQTLDN  60

Query  61   FSMKEVEDLISVLKSKSYQPYPSRRTYIEKKNGKKRPLGIPSFYDKLVQEVIRMILEAIY  120
             S+  ++ +I  +++++YQP P++R YI KKNGK RPLGI S  DKLVQEV+RMILEAIY
Sbjct  61   MSLPRINRIIESIRNRTYQPKPAKRKYIPKKNGKLRPLGITSTDDKLVQEVVRMILEAIY  120

Query  121  DssfssssHGYRKGKGCHSTLLEIKRTFTGSKWFIEGDIKGFFDNIEHHTLVTILKRRIK  180
            +++FS++SHG+R  ++CH++L ++K+ FTG  W++EGDIK+ FDN++HH LV +L++RI 
Sbjct  121  EPTFSNNSHGFRPKRSCHTALTQVKKNFTGVTWIVEGDIKACFDNFDHHVLVELLRKRIS  180

Query  181  DEAFIELIWKFLRAGYLEEWKFHNTYSGAPQGGIISPILSNIYLNELDVYMKKYQDRFES  240
            DEAFI LIWKFL+AGY+E+W+++ TYSG PQG+ ISPI +NIYL+ELD YM+ Y+++++ 
Sbjct  181  DEAFIGLIWKFLKAGYMEQWQYNCTYSGVPQGSGISPICANIYLSELDNYMQEYKEKYDC  240

Query  241  GKKRQINKEYSNLQYKVRKIQEKIDTAYLNGEVTRITELKEQQKVLKGKLLQTPYNNPMD  300
               R+      +     R+ +    +  L G      EL  + K  + K ++  Y NP +
Sbjct  241  EPERRRTTREYERA--SRRYRKARKA--LMGAEKSTPELVKEFKDSRRKKMNQHYYNPFE  296

Query  301  ENYRRLKYVRYADDFLIGVIGSKEDAILIKNEIASFlkeelklelsmekTLITNAFKKHA  360
            E +++++Y RYADDF+IGVIGSK DA  IK+++  FL+E L LE+S EKT +T++  K  
Sbjct  297  EGFKKIQYNRYADDFVIGVIGSKKDAEKIKEDVKIFLQEKLHLEMSEEKTKVTHS-SKPV  355

Query  361  KFLGFEIKVFKSEATRINSLGRASRVLNGKIQLKMPHEAWIKKLQKYQAIKM-----CAD  415
            ++LG+++KV+ S   +    G   RV  GK+ L MP E WIKK     AI++      + 
Sbjct  356  RYLGYDFKVIHSKNMKRCKNGDMKRVWYGKVFLYMPKEKWIKKAMERGAIQVKRNNDTGK  415

Query  416  GTWKPQPRGYFQHNEDLEIITQYNSEIRGLYNYYRLAENVSNHMHRFAYFMYYSMLKTFA  475
              W+P PR  + +  D EI++ +NSEIRGLYN+YR+AENV+  +H++ Y + YSMLKT+A
Sbjct  416  EMWRPMPRKDLMNRSDAEIVSTFNSEIRGLYNFYRIAENVGA-LHKYYYMVRYSMLKTLA  474

Query  476  SKYRTRTKQIRKKYEKYGQFTVQYETKKGMNKVHFIERKFPMTRNLSLEGTDILPNTRHV  535
            +K RT    I+K+    G + + Y+T KG +  +F +  F    +   + +D++P+ R  
Sbjct  475  GKHRTNVSVIKKRHMVNGVLRIPYDTTKGRKYCEFYHDGFRKHSDGYDNVADVMPSYRKY  534

Query  536  MSTTKLSDRIKAETCELCGASNVVIHMHHIKKLKNLRAKSNKSYLEKQMIARNRKTIALC  595
             S   + +RIKA  CE+CG     + MHH++ LK+L+++     +E++M+   RK++ALC
Sbjct  535  DSRHTIVNRIKAGVCEICGEHADYLCMHHVRTLKSLKGRDI---FEQKMLKMRRKSLALC  591

Query  596  KEC  598
             +C
Sbjct  592  PDC  594

27) Clocel_2353 in NC_014393


> NC_021994_R1|7|G7|529233401|YP_008394213.1|Enterococcus_faecium_Aus0085|+|4653..6470|-|EFAU085_00689|HNH 
endonuclease domain 
protein
Length=605

 Score =  411 bits (1547),  Expect = 7e-116, Method: Compositional matrix adjust.
 Identities = 269/609 (45%), Positives = 409/609 (68%), Gaps = 20/609 (3%)

Query  1    MRNPQNMLISLTKHSNNKNYKYERLYRLLYNEEMYLTAYQRIYTNEGNMTKGTDNQTIDG  60
            MRNP ++L SL   ++  NYKYERLYR LYN E YL AY  I  ++G+MT+G D QT+D 
Sbjct  1    MRNPIHVLKSLEEKASVSNYKYERLYRNLYNPEFYLLAYANIAKSQGSMTQGVDGQTLDN  60

Query  61   MSLKRITNIINSLRNESYQPKPSRRTYIPKKNGKLRPLGIPSFEDKLLQEVIRMILESIY  120
            MSL RI  II+S+RN +YQPKP++R YIPKKNGKLRPLGI S +DKL+QEV+RMILE+IY
Sbjct  61   MSLPRINRIIESIRNRTYQPKPAKRKYIPKKNGKLRPLGITSTDDKLVQEVVRMILEAIY  120

Query  121  EGYFEETSHGFRPNKSCHTALSKIQATFTGVKWFIEGDIKSFFDNINHDKMINILSERIN  180
            E  F + SHGFRP++SCHTAL++++  FTGV W++EGDIK+ FDN++H+ ++++L  RI+
Sbjct  121  EPTFSNNSHGFRPKRSCHTALTQVKKNFTGVTWIVEGDIKACFDNFDHHVLVELLRKRIS  180

Query  181  DQRFMRLIRKFLNAGYMEEWTFHKTFSGCPQGGIISPILANIYLDKFDKYMKEYVKLF--  238
            D+ F+ LI+KFL+AGYME+W ++ T+SG PQG+ ISPI ANIYL  +D+YM+EY   +  
Sbjct  181  DEAFIGLIWKFLKAGYMEQWQYNCTYSGVPQGSGISPICANIYLSELDNYMQEYKEKYDC  240

Query  239  ------RNGKRREVTLEYRQNKDALRLARVEFSKAVNETEKYKAITKIRELEKARVFIPY  292
                          +  YR+ + AL    +   K+  E      +  +++  + ++   Y
Sbjct  241  EPERRRTTREYERASRRYRKARKAL----MGAEKSTPEL-----VKEFKDSRRKKMNQHY  291

Query  293  GNPMDTEYKRLIYIRYADDWLCGVIGSKEECRKIKEDIKTFLAEKLQLELSEEKTLITNA  352
             NP +  +K++ Y RYADD + GVIGSK +  KIKED+K FL EKL+LE+SEEKT +T++
Sbjct  292  YNPFEEGFKKIQYNRYADDFVIGVIGSKKDAEKIKEDVKIFLQEKLHLEMSEEKTKVTHS  351

Query  353  KDKANFLSYKIYVRKSNLSKRDKAGRLVRNYTGRVVLEVSTDIIKKRLIDYSAMKLTYHQ  412
                 +L+Y + V  S+  KR K G + R   G+V L ++ +   K+ ++ +A+++  ++
Sbjct  352  SKPVRYLGYDFKVIHSKNMKRCKNGDMKRVWYGKVFLYMPKEKWIKKAMERGAIQVKRNN  411

Query  413  D--KEVWKPTARYNMKDCDDLEILDRYNSEIRGFYNYYCIANNSSIINSFKYIMEYSMyk  470
            D  KE+W+P +R ++ +  D EI+  +NSEIRG+YN+Y IA+N + ++ + Y++ YSM K
Sbjct  412  DTGKEMWRPMPRKDLMNRSDAEIVSTFNSEIRGLYNFYRIAENVGALHKYYYMVRYSMLK  471

Query  471  tyatkyrttkaDIIEKFRINKDFGIRYKNSKGIERVRLFYNEGFKRQKECLRKNADLIPD  530
            T A K RT  + I  +  +N  + I Y  +KG  +   FY++GF+++ +   + AD++P 
Sbjct  472  TLAGKHRTNVSVIKKRHMVNGVLRIPYDTTKG-RKYCEFYHDGFRKHSDGYDNVADVMPS  530

Query  531  GIKYFSSTSLIERLRANKCEICGKENATIEIHHIRKLKDLQGKNFWETLMIARRRKTLAL  590
              KY S  ++++R++A  CEICG +   + +HH+R LK L+G+++ E  M+  RRK+LAL
Sbjct  531  YRKYDSRHTIVNRIKAGVCEICGEHADYLCMHHVRTLKSLKGRDIFEQKMLKMRRKSLAL  590

Query  591  CLECHKKLH  599
            C +C   LH
Sbjct  591  CPDCFELLH  599

28) CT43_P281092 in NC_017203


> NC_021994_R1|7|G7|529233401|YP_008394213.1|Enterococcus_faecium_Aus0085|+|4653..6470|-|EFAU085_00689|HNH 
endonuclease domain 
protein
Length=605

 Score =  407 bits (1533),  Expect = 8e-115, Method: Compositional matrix adjust.
 Identities = 261/603 (44%), Positives = 405/603 (68%), Gaps = 14/603 (2%)

Query  1    MQCPKIVLSNLRTKSLNKEYQYTRLYRNLYNPDFFLLAYDNLSKNDGALTIGVDQRSIDG  60
            M+ P  VL +L  K+   +Y+Y RLYRNLYNP+F+LLAY N++K++G++T GVD +++D 
Sbjct  1    MRNPIHVLKSLEEKASVSNYKYERLYRNLYNPEFYLLAYANIAKSQGSMTQGVDGQTLDN  60

Query  61   FSMKEVEDLISVLKSKSYQPYPSRRTYIEKKNGKKRPLGIPSFYDKLVQEVIRMILEAIY  120
             S+  ++ +I  +++++YQP P++R YI KKNGK RPLGI S  DKLVQEV+RMILEAIY
Sbjct  61   MSLPRINRIIESIRNRTYQPKPAKRKYIPKKNGKLRPLGITSTDDKLVQEVVRMILEAIY  120

Query  121  DssfssssHGYRKGKGCHSALLEIKRTFTGSKWFIEGDIKGFFDNIEHHTLVTILKRRIK  180
            +++FS++SHG+R  ++CH+AL ++K+ FTG  W++EGDIK+ FDN++HH LV +L++RI 
Sbjct  121  EPTFSNNSHGFRPKRSCHTALTQVKKNFTGVTWIVEGDIKACFDNFDHHVLVELLRKRIS  180

Query  181  DEAFIELIWKFLRAGYLEEWKFHNTYSGApqggiispiisyiyLNELDTYMKKYQDRFES  240
            DEAFI LIWKFL+AGY+E+W+++ TYSG PQG+ ISPI + IYL+ELD YM+ Y+++++ 
Sbjct  181  DEAFIGLIWKFLKAGYMEQWQYNCTYSGVPQGSGISPICANIYLSELDNYMQEYKEKYDC  240

Query  241  GKKRQINKEYSNLQYKVRKIQEKIDTAYLNGEVTRITELKEQQKVLKGKLLQTPYNNPMD  300
               R+      +     R+ +    +  L G      EL  + K  + K ++  Y NP +
Sbjct  241  EPERRRTTREYERA--SRRYRKARKA--LMGAEKSTPELVKEFKDSRRKKMNQHYYNPFE  296

Query  301  ENYRRLKYVRYADDFLIGVIGSKEDAILIKNEIASFLKEEIKLELSMEKTLITNAFKKHA  360
            E +++++Y RYADDF+IGVIGSK DA  IK+++  FL+E + LE+S EKT +T++  K  
Sbjct  297  EGFKKIQYNRYADDFVIGVIGSKKDAEKIKEDVKIFLQEKLHLEMSEEKTKVTHS-SKPV  355

Query  361  KFLGFEIKVFKSEATRINSLGRASRVLNGKIQLKMPHEAWIKKLQKYQAIKM-----CAD  415
            ++LG+++KV+ S   +    G   RV  GK+ L MP E WIKK     AI++      + 
Sbjct  356  RYLGYDFKVIHSKNMKRCKNGDMKRVWYGKVFLYMPKEKWIKKAMERGAIQVKRNNDTGK  415

Query  416  GTWKPQPRGYFQHNEDLEIITQYNSEIRGLYNYYRLAENVSNHMHRFAYFMYYSMLKTFA  475
              W+P PR  + +  D EI++ +NSEIRGLYN+YR+AENV+  +H++ Y + YSMLKT+A
Sbjct  416  EMWRPMPRKDLMNRSDAEIVSTFNSEIRGLYNFYRIAENVGA-LHKYYYMVRYSMLKTLA  474

Query  476  SKYRTRTKQIREKYEKYGQFTVQYETKKGMNKVHFIERKFPMTRNLSLEGTDILPNTRHV  535
            +K RT    I+ +    G + + Y+T KG +  +F +  F    +   + +D++P+ R  
Sbjct  475  GKHRTNVSVIKKRHMVNGVLRIPYDTTKGRKYCEFYHDGFRKHSDGYDNVADVMPSYRKY  534

Query  536  MSTTKLSDRIKAETCELCGTSNVVIHMHHIKRLKNLRAKSNKSYLEQQMIARNRKTIALC  595
             S   + +RIKA  CE+CG     + MHH++ LK+L+++     +EQ+M+   RK++ALC
Sbjct  535  DSRHTIVNRIKAGVCEICGEHADYLCMHHVRTLKSLKGRDI---FEQKMLKMRRKSLALC  591

Query  596  KEC  598
             +C
Sbjct  592  PDC  594

29) H175_285p099 in NC_020384


> NC_021994_R1|7|G7|529233401|YP_008394213.1|Enterococcus_faecium_Aus0085|+|4653..6470|-|EFAU085_00689|HNH 
endonuclease domain 
protein
Length=605

 Score =  407 bits (1533),  Expect = 8e-115, Method: Compositional matrix adjust.
 Identities = 261/603 (44%), Positives = 405/603 (68%), Gaps = 14/603 (2%)

Query  1    MQCPKIVLSNLRTKSLNKEYQYTRLYRNLYNPDFFLLAYDNLSKNDGALTIGVDQRSIDG  60
            M+ P  VL +L  K+   +Y+Y RLYRNLYNP+F+LLAY N++K++G++T GVD +++D 
Sbjct  1    MRNPIHVLKSLEEKASVSNYKYERLYRNLYNPEFYLLAYANIAKSQGSMTQGVDGQTLDN  60

Query  61   FSMKEVEDLISVLKSKSYQPYPSRRTYIEKKNGKKRPLGIPSFYDKLVQEVIRMILEAIY  120
             S+  ++ +I  +++++YQP P++R YI KKNGK RPLGI S  DKLVQEV+RMILEAIY
Sbjct  61   MSLPRINRIIESIRNRTYQPKPAKRKYIPKKNGKLRPLGITSTDDKLVQEVVRMILEAIY  120

Query  121  DssfssssHGYRKGKGCHSALLEIKRTFTGSKWFIEGDIKGFFDNIEHHTLVTILKRRIK  180
            +++FS++SHG+R  ++CH+AL ++K+ FTG  W++EGDIK+ FDN++HH LV +L++RI 
Sbjct  121  EPTFSNNSHGFRPKRSCHTALTQVKKNFTGVTWIVEGDIKACFDNFDHHVLVELLRKRIS  180

Query  181  DEAFIELIWKFLRAGYLEEWKFHNTYSGApqggiispiisyiyLNELDTYMKKYQDRFES  240
            DEAFI LIWKFL+AGY+E+W+++ TYSG PQG+ ISPI + IYL+ELD YM+ Y+++++ 
Sbjct  181  DEAFIGLIWKFLKAGYMEQWQYNCTYSGVPQGSGISPICANIYLSELDNYMQEYKEKYDC  240

Query  241  GKKRQINKEYSNLQYKVRKIQEKIDTAYLNGEVTRITELKEQQKVLKGKLLQTPYNNPMD  300
               R+      +     R+ +    +  L G      EL  + K  + K ++  Y NP +
Sbjct  241  EPERRRTTREYERA--SRRYRKARKA--LMGAEKSTPELVKEFKDSRRKKMNQHYYNPFE  296

Query  301  ENYRRLKYVRYADDFLIGVIGSKEDAILIKNEIASFLKEEIKLELSMEKTLITNAFKKHA  360
            E +++++Y RYADDF+IGVIGSK DA  IK+++  FL+E + LE+S EKT +T++  K  
Sbjct  297  EGFKKIQYNRYADDFVIGVIGSKKDAEKIKEDVKIFLQEKLHLEMSEEKTKVTHS-SKPV  355

Query  361  KFLGFEIKVFKSEATRINSLGRASRVLNGKIQLKMPHEAWIKKLQKYQAIKM-----CAD  415
            ++LG+++KV+ S   +    G   RV  GK+ L MP E WIKK     AI++      + 
Sbjct  356  RYLGYDFKVIHSKNMKRCKNGDMKRVWYGKVFLYMPKEKWIKKAMERGAIQVKRNNDTGK  415

Query  416  GTWKPQPRGYFQHNEDLEIITQYNSEIRGLYNYYRLAENVSNHMHRFAYFMYYSMLKTFA  475
              W+P PR  + +  D EI++ +NSEIRGLYN+YR+AENV+  +H++ Y + YSMLKT+A
Sbjct  416  EMWRPMPRKDLMNRSDAEIVSTFNSEIRGLYNFYRIAENVGA-LHKYYYMVRYSMLKTLA  474

Query  476  SKYRTRTKQIREKYEKYGQFTVQYETKKGMNKVHFIERKFPMTRNLSLEGTDILPNTRHV  535
            +K RT    I+ +    G + + Y+T KG +  +F +  F    +   + +D++P+ R  
Sbjct  475  GKHRTNVSVIKKRHMVNGVLRIPYDTTKGRKYCEFYHDGFRKHSDGYDNVADVMPSYRKY  534

Query  536  MSTTKLSDRIKAETCELCGTSNVVIHMHHIKRLKNLRAKSNKSYLEQQMIARNRKTIALC  595
             S   + +RIKA  CE+CG     + MHH++ LK+L+++     +EQ+M+   RK++ALC
Sbjct  535  DSRHTIVNRIKAGVCEICGEHADYLCMHHVRTLKSLKGRDI---FEQKMLKMRRKSLALC  591

Query  596  KEC  598
             +C
Sbjct  592  PDC  594

30) Smon_0664 in NC_013515


> NC_021994_R1|7|G7|529233401|YP_008394213.1|Enterococcus_faecium_Aus0085|+|4653..6470|-|EFAU085_00689|HNH 
endonuclease domain 
protein
Length=605

 Score =  398 bits (1499),  Expect = 4e-112, Method: Compositional matrix adjust.
 Identities = 273/610 (45%), Positives = 408/610 (67%), Gaps = 11/610 (1%)

Query  1    MRNPNNVLISLRKHSKEENYTYEKLYRNLYNIDLFLQAYQNIYANTGNMTKGVDNQTISA  60
            MRNP +VL SL   +   NY YE+LYRNLYN +++L AY NI  + G+MT+GVD QT+  
Sbjct  1    MRNPIHVLKSLEEKASVSNYKYERLYRNLYNPEFYLLAYANIAKSQGSMTQGVDGQTLDN  60

Query  61   MSLERINKIIDSLKDESYSPTPTKRVYIPKKNGKLRPLGIPSIDDKLVQEVCRMLLNSIY  120
            MSL RIN+II+S+++ +Y P P+KR YIPKKNGKLRPLGI S DDKLVQEV RM+L++IY
Sbjct  61   MSLPRINRIIESIRNRTYQPKPAKRKYIPKKNGKLRPLGITSTDDKLVQEVVRMILEAIY  120

Query  121  DESFEDISHGFKDNRSCHTALRQIQNRFVRCKWFVEGDIKDFFDNINHNIMIDILSKRID  180
            + +F + SHGF+ +RSCHTAL Q+++ F    W+VEGDIK  FDN++H++++++L KRI 
Sbjct  121  EPTFSNNSHGFRPKRSCHTALTQVKKNFTGVTWIVEGDIKACFDNFDHHVLVELLRKRIS  180

Query  181  DkrflrlirkflrAGYMEQNEYLNTYSGMPQGSIISPILSNIYLDKFDKYMQSYKESFDK  240
            D  F+ LI+KFL+AGYMEQ +Y  TYSG+PQGS ISPI +NIYL  +D+YMQ YKE +D 
Sbjct  181  DEAFIGLIWKFLKAGYMEQWQYNCTYSGVPQGSGISPICANIYLSELDNYMQEYKEKYDC  240

Query  241  GTKRKQNKEYKALYDRRKRLENKLRKTTNKIEIDNIKSEIEEINKRYSNIPCLNPMDKNF  300
               R++         RR R   K    ++K   + +K E+ +  ++  N    NP +  F
Sbjct  241  EPERRRTTREYERASRRYRKARKALMGAEKSTPELVK-EFKDSRRKKMNQHYYNPFEEGF  299

Query  301  KRIQYVRYADDFIIGIIGSKADAEKVKQDISQFIKSELNLELSDEKTLVTKSTNRAKFLG  360
            K+IQY RYADDF+IG+IGSK DAEK+K+D+  F++  L+LE+S+EKT VT S++  ++LG
Sbjct  300  KKIQYNRYADDFVIGVIGSKKDAEKIKEDVKIFLQEKLHLEMSEEKTKVTHSSKPVRYLG  359

Query  361  FDIRVTPRSNHTKRTKVGIKARNFGGHVRLELSTSTIQNKLTELGALKIKNLN--GKEVW  418
            +D++V  +S++ KR K G   R   G V L ++     +K  E GA+++K  N  GKE+W
Sbjct  360  YDFKVI-HSKNMKRCKNGDMKRVWYGKVFLYMPKEKWIKKAMERGAIQVKRNNDTGKEMW  418

Query  419  FPKERSNLTSRTDLSILEQYNGEIRGFCNYYRLANNSSKLHKFRYIMEYSLYKTLACKYR  478
             P  R +L +R+D  I+  +N+EIRG+ N+YR+A+N + LHK+ Y++ YS+ KTLA K R
Sbjct  419  RPMPRKDLMNRSDAEIVSTFNSEIRGLYNFYRIAENVGALHKYYYMVRYSMLKTLAGKHR  478

Query  479  TKVTDIITRYHIGKDFGISYTDKNGNNKIRFLWKDSLARKEIPQDDNADVIHKQKFYLKK  538
            T+V+ I  R  +   + I+Y   +G +   F   D++ +     D+ ADV+   + Y  +
Sbjct  479  TNVSVIKKRHMVNGVLRIPYDTTKGRKYCEFY-HDGFRKHSDGYDNVADVMPSYRKYDSR  537

Query  539  PTLGLRLKNNKCEWCGKETNNLKVYQVKKLKDLTDEYAWHVF---MKSINRKTLVICNEC  595
             T+  R+K   CE CG +++ L + +V+ LK L    ++++F   M  + RK+L +C +C
Sbjct  538  HTIVNRIKAGVCEICGEHADYLCMHHVRTLKSLK---GRDIFEQKMLKMRRKSLALCPDC  594

Query  596  FEKINNSNEE  605
            FE +++++E 
Sbjct  595  FELLHETKES  604

31) BCQ_PI011 in NC_011973


> NC_021994_R1|7|G7|529233401|YP_008394213.1|Enterococcus_faecium_Aus0085|+|4653..6470|-|EFAU085_00689|HNH 
endonuclease domain 
protein
Length=605

 Score =  392 bits (1476),  Expect = 3e-110, Method: Compositional matrix adjust.
 Identities = 269/613 (44%), Positives = 411/613 (68%), Gaps = 16/613 (2%)

Query  3    MRNPVYVLNTLSKNTIKENYKFNRLYRNLYNPEFYYKAYQEIYANPGNMTRGTINNTVDG  62
            MRNP+ VL++L  ++   NYK++RLYRNLYNPEFY  AY +I  + G+MT+G   +T+D 
Sbjct  1    MRNPIHVLKSLEEKASVSNYKYERLYRNLYNPEFYLLAYANIAKSQGSMTQGVDGQTLDN  60

Query  63   FSKNRVSkiinnikngnykPTPVKRVYIDKKGSKKKRPLGIPTFDDKLVQLVIKYILEAI  122
             S  R+++II++I+N  Y+P P KR YI KK +K  RPLGI + DDKLVQ V++ ILEAI
Sbjct  61   MSLPRINRIIESIRNRTYQPKPAKRKYIPKKNGKL-RPLGITSTDDKLVQEVVRMILEAI  119

Query  123  YEPNFSENSHGFRKNRGCHTALKQIKKSGSGTKWFIEGDIQGFFDNIDHHILINLLRKRI  182
            YEP FS+NSHGFR +R+CHTAL Q+KK+ +G  W++EGDI++ FDN+DHH+L++LLRKRI
Sbjct  120  YEPTFSNNSHGFRPKRSCHTALTQVKKNFTGVTWIVEGDIKACFDNFDHHVLVELLRKRI  179

Query  183  NDETLIGLIWKFLRAGYMEDWQFHKTFSGTPQGGILSPLLANIYLNELDIYMEKYAERFG  242
            +DE++IGLIWKFL+AGYME+WQ++ T+SG PQG+ +SP+ ANIYL+ELD YM+ Y E+++
Sbjct  180  SDEAFIGLIWKFLKAGYMEQWQYNCTYSGVPQGSGISPICANIYLSELDNYMQEYKEKYD  239

Query  243  KGQPKDREVDKRYQYLHLKIKRGRKKADLLREQGKLNESQELIHQVNEWIKERGQRPYYN  302
              +P  R   + Y+    + +++RK   L+   G  + + EL+ + ++  + + ++ YYN
Sbjct  240  -CEPERRRTTREYERASRRYRKARK--ALM---GAEKSTPELVKEFKDSRRKKMNQHYYN  293

Query  303  PMSDKFKSLKYVRYADDFIVMLIGSKDDANAIKSDIAQFLNeelkltlseektlITHSSK  362
            P  + FK ++Y RYADDF++ +IGSK DA+ IK D+  FL+E L L +SEEKT +THSSK
Sbjct  294  PFEEGFKKIQYNRYADDFVIGVIGSKKDAEKIKEDVKIFLQEKLHLEMSEEKTKVTHSSK  353

Query  363  KAKFLGYNVNITRNELFTKYSVKGAKRRHHNLKVRLEIPHEAWRNKLLVLNVLEMK--YV  420
              ++LGY+ ++ ++    +   +G  +R    KV L +P E W +K +    +++K    
Sbjct  354  PVRYLGYDFKVIHSKNMKRCK-NGDMKRVWYGKVFLYMPKEKWIKKAMERGAIQVKRNND  412

Query  421  NGKETWKPKHRPEMAHLDDLEILHNYVLQIRGMYNYYKYAVNSTVLQKFSYVLEYSMYKT  480
             GKE W+P  R ++ +  D EI+  +  +IRG+YN+Y+ A N   L+K+ Y++ YSM KT
Sbjct  413  TGKEMWRPMPRKDLMNRSDAEIVSTFNSEIRGLYNFYRIAENVGALHKYYYMVRYSMLKT  472

Query  481  FANkykssigkikgkyCKNGVFVVNYKDKKGKQRSHSFYKEGFRTVDITKMKTQENNIDN  540
            +A K +++++ IK +   NGV+ + Y   KG+ +   FY +GFR          +N  D 
Sbjct  473  LAGKHRTNVSVIKKRHMVNGVLRIPYDTTKGR-KYCEFYHDGFRKHS----DGYDNVADV  527

Query  541  MVASRAHMSTTSLIDRLSANKCEHCGKTDSNLVMHHVRKMKDVEKGKAKWQKLMIARRRK  600
            M + R   S  ++++R+ A  CE CG     L MHHVR +K + KG+   ++ M+  RRK
Sbjct  528  MPSYRKYDSRHTIVNRIKAGVCEICGEHADYLCMHHVRTLKSL-KGRDIFEQKMLKMRRK  586

Query  601  TLAVCEDCHNEIH  613
            +LA+C DC + +H
Sbjct  587  SLALCPDCFELLH  599

32) BCG9842_B4556 in NC_011772


> NC_021994_R1|7|G7|529233401|YP_008394213.1|Enterococcus_faecium_Aus0085|+|4653..6470|-|EFAU085_00689|HNH 
endonuclease domain 
protein
Length=605

 Score =  391 bits (1469),  Expect = 1e-109, Method: Compositional matrix adjust.
 Identities = 276/608 (46%), Positives = 411/608 (68%), Gaps = 12/608 (1%)

Query  1    MRSPKIVLENLASHSKKAGykykklyrnlynPLFFLEAYQNIYASEGNMTAGTDGKTIDG  60
            MR+P  VL +L   +  + YKY +LYRNLYNP F+L AY NI  S+G+MT G DG+T+D 
Sbjct  1    MRNPIHVLKSLEEKASVSNYKYERLYRNLYNPEFYLLAYANIAKSQGSMTQGVDGQTLDN  60

Query  61   MSERRISELIDKLRDYSYQPKPVRRVYIPKKNGKKRPLGIPSVEDKLVQEVIKNLLESIY  120
            MS  RI+ +I+ +R+ +YQPKP +R YIPKKNGK RPLGI S +DKLVQEV++ +LE+IY
Sbjct  61   MSLPRINRIIESIRNRTYQPKPAKRKYIPKKNGKLRPLGITSTDDKLVQEVVRMILEAIY  120

Query  121  EPTFSKLSHGFRPEKSCHTALFQVKSTFTGSRWFIEGDIEGFFDNINHHILIHTLRKRID  180
            EPTFS+ SHGFRP +SCHTAL QVK  FTG  W++EGDI + FDN++HH+L++ LRKRI 
Sbjct  121  EPTFSNNSHGFRPKRSCHTALTQVKKNFTGVTWIVEGDIKACFDNFDHHVLVELLRKRIS  180

Query  181  DEQFIALIWKFLRAGYLEDWKFHKTFSGTPQGGILSPLLANIYLNELDNFMNQYKSTFDV  240
            DE FI+LIWKFL+AGY+E+W+++ T+SG PQG+ +SP+ ANIYL+ELDN+M++YK  +D 
Sbjct  181  DEAFIGLIWKFLKAGYMEQWQYNCTYSGVPQGSGISPICANIYLSELDNYMQEYKEKYDC  240

Query  241  GKIRRTNPTYSKIQHQINkakkklreakekDEVREKELTNKIRELLAEREHTPQGY--PM  298
               RR         ++ ++  +K R A    E    EL + +++  + R    Q Y  P 
Sbjct  241  EPERRRTTR---EYERASRRYRKARKALMGAEKSTPELVKEFKD--SRRKKMNQHYYNPF  295

Query  299  DENYKRIQYVRYADDFLIGVIGSKEDANRAKKDIANFlksklkltlseektlITNTRNKA  358
            +E +K+IQY RYADDF+IGVIGSK DA++ K D+  FL+ KL L +SEEKT +T++ +  
Sbjct  296  EEGFKKIQYNRYADDFVIGVIGSKKDAEKIKEDVKIFLQEKLHLEMSEEKTKVTHSSKPV  355

Query  359  RFLGYDVKVGRDFHSKRRSDGIKTRAFSLKCELYMPTDLVYSRLFKKGVIKINQKTGQ--  416
            R+LGYD KV +  + KR  +G   R    K  LYMP +    +   +G I+++++ +   
Sbjct  356  RYLGYDFKVIHSKNMKRCKNGDMKRVWYGKVFLYMPKEKWIKKAMERGAIQVKRNNDTGK  415

Query  417  --WKPIHRPELIKLVPLEILRNYNAQIRGTYQYYQLAVNVCHLNSYKYLLEYSMYKTLAN  474
              W+P+ R +L++    EI+  +N++IRG Y++Y++A NV  L+ Y Y++ YSM KTLA 
Sbjct  416  EMWRPMPRKDLMNRSDAEIVSTFNSEIRGLYNFYRIAENVGALHKYYYMVRYSMLKTLAG  475

Query  475  KYRTTLGKAKQKFMVNGIFQVSYKIKSGKKTEVLYDKGFRRNKAPITKKDIEKLPSEVSY  534
            K RT ++  K++ MVNG+++++Y    G+K   +Y+ GFR++     +   + +PS   Y
Sbjct  476  KHRTNVSVIKKRHMVNGVLRIPYDTTKGRKYCEFYHDGFRKHSDGYDNVA-DVMPSYRKY  534

Query  535  QSRTSLIQRLMANQCEWCKAEEGSMEVHHVRklknlkgkkkWERQMIARNRKTMILCRKC  594
            +SR ++++R+ A  CE C  + + + +HHVR LK+LKG+   E++M+   RK++ LC  C
Sbjct  535  DSRHTIVNRIKAGVCEICGEHADYLCMHHVRTLKSLKGRDIFEQKMLKMRRKSLALCPDC  594

Query  595  HRDLHNGK  602
               LH+ K
Sbjct  595  FELLHETK  602

33) BCG9842_B1762 in NC_011772


> NC_021994_R1|7|G7|529233401|YP_008394213.1|Enterococcus_faecium_Aus0085|+|4653..6470|-|EFAU085_00689|HNH 
endonuclease domain 
protein
Length=605

 Score =  391 bits (1469),  Expect = 1e-109, Method: Compositional matrix adjust.
 Identities = 276/608 (46%), Positives = 411/608 (68%), Gaps = 12/608 (1%)

Query  1    MRSPKIVLENLASHSKKAGykykklyrnlynPLFFLEAYQNIYASEGNMTAGTDGKTIDG  60
            MR+P  VL +L   +  + YKY +LYRNLYNP F+L AY NI  S+G+MT G DG+T+D 
Sbjct  1    MRNPIHVLKSLEEKASVSNYKYERLYRNLYNPEFYLLAYANIAKSQGSMTQGVDGQTLDN  60

Query  61   MSERRISELIDKLRDYSYQPKPVRRVYIPKKNGKKRPLGIPSVEDKLVQEVIKNLLESIY  120
            MS  RI+ +I+ +R+ +YQPKP +R YIPKKNGK RPLGI S +DKLVQEV++ +LE+IY
Sbjct  61   MSLPRINRIIESIRNRTYQPKPAKRKYIPKKNGKLRPLGITSTDDKLVQEVVRMILEAIY  120

Query  121  EPTFSKLSHGFRPEKSCHTALFQVKSTFTGSRWFIEGDIEGFFDNINHHILIHTLRKRID  180
            EPTFS+ SHGFRP +SCHTAL QVK  FTG  W++EGDI + FDN++HH+L++ LRKRI 
Sbjct  121  EPTFSNNSHGFRPKRSCHTALTQVKKNFTGVTWIVEGDIKACFDNFDHHVLVELLRKRIS  180

Query  181  DEQFIALIWKFLRAGYLEDWKFHKTFSGTPQGGILSPLLANIYLNELDNFMNQYKSTFDV  240
            DE FI+LIWKFL+AGY+E+W+++ T+SG PQG+ +SP+ ANIYL+ELDN+M++YK  +D 
Sbjct  181  DEAFIGLIWKFLKAGYMEQWQYNCTYSGVPQGSGISPICANIYLSELDNYMQEYKEKYDC  240

Query  241  GKIRRTNPTYSKIQHQINkakkklreakekDEVREKELTNKIRELLAEREHTPQGY--PM  298
               RR         ++ ++  +K R A    E    EL + +++  + R    Q Y  P 
Sbjct  241  EPERRRTTR---EYERASRRYRKARKALMGAEKSTPELVKEFKD--SRRKKMNQHYYNPF  295

Query  299  DENYKRIQYVRYADDFLIGVIGSKEDANRAKKDIANFlksklkltlseektlITNTRNKA  358
            +E +K+IQY RYADDF+IGVIGSK DA++ K D+  FL+ KL L +SEEKT +T++ +  
Sbjct  296  EEGFKKIQYNRYADDFVIGVIGSKKDAEKIKEDVKIFLQEKLHLEMSEEKTKVTHSSKPV  355

Query  359  RFLGYDVKVGRDFHSKRRSDGIKTRAFSLKCELYMPTDLVYSRLFKKGVIKINQKTGQ--  416
            R+LGYD KV +  + KR  +G   R    K  LYMP +    +   +G I+++++ +   
Sbjct  356  RYLGYDFKVIHSKNMKRCKNGDMKRVWYGKVFLYMPKEKWIKKAMERGAIQVKRNNDTGK  415

Query  417  --WKPIHRPELIKLVPLEILRNYNAQIRGTYQYYQLAVNVCHLNSYKYLLEYSMYKTLAN  474
              W+P+ R +L++    EI+  +N++IRG Y++Y++A NV  L+ Y Y++ YSM KTLA 
Sbjct  416  EMWRPMPRKDLMNRSDAEIVSTFNSEIRGLYNFYRIAENVGALHKYYYMVRYSMLKTLAG  475

Query  475  KYRTTLGKAKQKFMVNGIFQVSYKIKSGKKTEVLYDKGFRRNKAPITKKDIEKLPSEVSY  534
            K RT ++  K++ MVNG+++++Y    G+K   +Y+ GFR++     +   + +PS   Y
Sbjct  476  KHRTNVSVIKKRHMVNGVLRIPYDTTKGRKYCEFYHDGFRKHSDGYDNVA-DVMPSYRKY  534

Query  535  QSRTSLIQRLMANQCEWCKAEEGSMEVHHVRklknlkgkkkWERQMIARNRKTMILCRKC  594
            +SR ++++R+ A  CE C  + + + +HHVR LK+LKG+   E++M+   RK++ LC  C
Sbjct  535  DSRHTIVNRIKAGVCEICGEHADYLCMHHVRTLKSLKGRDIFEQKMLKMRRKSLALCPDC  594

Query  595  HRDLHNGK  602
               LH+ K
Sbjct  595  FELLHETK  602

34) BCG9842_B5597 in NC_011772


> NC_021994_R1|7|G7|529233401|YP_008394213.1|Enterococcus_faecium_Aus0085|+|4653..6470|-|EFAU085_00689|HNH 
endonuclease domain 
protein
Length=605

 Score =  391 bits (1469),  Expect = 1e-109, Method: Compositional matrix adjust.
 Identities = 276/608 (46%), Positives = 411/608 (68%), Gaps = 12/608 (1%)

Query  1    MRSPKIVLENLASHSKKAGykykklyrnlynPLFFLEAYQNIYASEGNMTAGTDGKTIDG  60
            MR+P  VL +L   +  + YKY +LYRNLYNP F+L AY NI  S+G+MT G DG+T+D 
Sbjct  1    MRNPIHVLKSLEEKASVSNYKYERLYRNLYNPEFYLLAYANIAKSQGSMTQGVDGQTLDN  60

Query  61   MSERRISELIDKLRDYSYQPKPVRRVYIPKKNGKKRPLGIPSVEDKLVQEVIKNLLESIY  120
            MS  RI+ +I+ +R+ +YQPKP +R YIPKKNGK RPLGI S +DKLVQEV++ +LE+IY
Sbjct  61   MSLPRINRIIESIRNRTYQPKPAKRKYIPKKNGKLRPLGITSTDDKLVQEVVRMILEAIY  120

Query  121  EPTFSKLSHGFRPEKSCHTALFQVKSTFTGSRWFIEGDIEGFFDNINHHILIHTLRKRID  180
            EPTFS+ SHGFRP +SCHTAL QVK  FTG  W++EGDI + FDN++HH+L++ LRKRI 
Sbjct  121  EPTFSNNSHGFRPKRSCHTALTQVKKNFTGVTWIVEGDIKACFDNFDHHVLVELLRKRIS  180

Query  181  DEQFIALIWKFLRAGYLEDWKFHKTFSGTPQGGILSPLLANIYLNELDNFMNQYKSTFDV  240
            DE FI+LIWKFL+AGY+E+W+++ T+SG PQG+ +SP+ ANIYL+ELDN+M++YK  +D 
Sbjct  181  DEAFIGLIWKFLKAGYMEQWQYNCTYSGVPQGSGISPICANIYLSELDNYMQEYKEKYDC  240

Query  241  GKIRRTNPTYSKIQHQINkakkklreakekDEVREKELTNKIRELLAEREHTPQGY--PM  298
               RR         ++ ++  +K R A    E    EL + +++  + R    Q Y  P 
Sbjct  241  EPERRRTTR---EYERASRRYRKARKALMGAEKSTPELVKEFKD--SRRKKMNQHYYNPF  295

Query  299  DENYKRIQYVRYADDFLIGVIGSKEDANRAKKDIANFlksklkltlseektlITNTRNKA  358
            +E +K+IQY RYADDF+IGVIGSK DA++ K D+  FL+ KL L +SEEKT +T++ +  
Sbjct  296  EEGFKKIQYNRYADDFVIGVIGSKKDAEKIKEDVKIFLQEKLHLEMSEEKTKVTHSSKPV  355

Query  359  RFLGYDVKVGRDFHSKRRSDGIKTRAFSLKCELYMPTDLVYSRLFKKGVIKINQKTGQ--  416
            R+LGYD KV +  + KR  +G   R    K  LYMP +    +   +G I+++++ +   
Sbjct  356  RYLGYDFKVIHSKNMKRCKNGDMKRVWYGKVFLYMPKEKWIKKAMERGAIQVKRNNDTGK  415

Query  417  --WKPIHRPELIKLVPLEILRNYNAQIRGTYQYYQLAVNVCHLNSYKYLLEYSMYKTLAN  474
              W+P+ R +L++    EI+  +N++IRG Y++Y++A NV  L+ Y Y++ YSM KTLA 
Sbjct  416  EMWRPMPRKDLMNRSDAEIVSTFNSEIRGLYNFYRIAENVGALHKYYYMVRYSMLKTLAG  475

Query  475  KYRTTLGKAKQKFMVNGIFQVSYKIKSGKKTEVLYDKGFRRNKAPITKKDIEKLPSEVSY  534
            K RT ++  K++ MVNG+++++Y    G+K   +Y+ GFR++     +   + +PS   Y
Sbjct  476  KHRTNVSVIKKRHMVNGVLRIPYDTTKGRKYCEFYHDGFRKHSDGYDNVA-DVMPSYRKY  534

Query  535  QSRTSLIQRLMANQCEWCKAEEGSMEVHHVRklknlkgkkkWERQMIARNRKTMILCRKC  594
            +SR ++++R+ A  CE C  + + + +HHVR LK+LKG+   E++M+   RK++ LC  C
Sbjct  535  DSRHTIVNRIKAGVCEICGEHADYLCMHHVRTLKSLKGRDIFEQKMLKMRRKSLALCPDC  594

Query  595  HRDLHNGK  602
               LH+ K
Sbjct  595  FELLHETK  602

35) AL1_03430 in NC_021030


> NC_021994_R1|7|G7|529233401|YP_008394213.1|Enterococcus_faecium_Aus0085|+|4653..6470|-|EFAU085_00689|HNH 
endonuclease domain 
protein
Length=605

 Score =  382 bits (1435),  Expect = 4e-107, Method: Compositional matrix adjust.
 Identities = 250/552 (46%), Positives = 385/552 (70%), Gaps = 8/552 (1%)

Query  1    MRNPERVLNSLSEHSKVSSYKFERLYRVLFNSEMFLLAYHNIQGRQGNMTEGSDGKTIDG  60
            MRNP +VL+SL E + VS+YK+ERLYR L+N+E +LLAY NI   QG+MT+G DG+T+D 
Sbjct  1    MRNPIHVLKSLEEKASVSNYKYERLYRNLYNPEFYLLAYANIAKSQGSMTQGVDGQTLDN  60

Query  61   MSLKRIENLIDALKDESYQPKPARRMYIPKKNGNMRPLGIPSIDDKLVQEVLRMLLEAIY  120
            MSL RI+ +I+++++ +YQPKPA+R YIPKKNG++RPLGI S DDKLVQEV+RM+LEAIY
Sbjct  61   MSLPRINRIIESIRNRTYQPKPAKRKYIPKKNGKLRPLGITSTDDKLVQEVVRMILEAIY  120

Query  121  EGSFENTSHGFRPKRSCHTALIQVQKNFTAAKWFIEGDIEGFFDNINHDVLIGILKERIA  180
            E +F N SHGFRPKRSCHTAL QV+KNFT+  W++EGDI + FDN++H+VL+ +L+ RI+
Sbjct  121  EPTFSNNSHGFRPKRSCHTALTQVKKNFTGVTWIVEGDIKACFDNFDHHVLVELLRKRIS  180

Query  181  DDRFIRLMWKFLKAGYIEDWTFHRTYSGTPQGGIISPILANIYLDKLDKYMKEYACQFDR  240
            D+ FI L+WKFLKAGY+E+W ++ TYSG PQG+ ISPI ANIYL  LD+YM+EY  ++D 
Sbjct  181  DEAFIGLIWKFLKAGYMEQWQYNCTYSGVPQGSGISPICANIYLSELDNYMQEYKEKYDC  240

Query  241  GDRRAMNLEYKRYSRKIWWLGTKLKQTEDKDTRKELIDAIKQHQKNRMHLPSVDEMDEGY  300
               R         + +  + + K     +K T  EL+  +K+ ++++M+    +  +EG+
Sbjct  241  EPERRRTTREYERASRRYRKARKALMGAEKSTP-ELVKEFKDSRRKKMNQHYYNPFEEGF  299

Query  301  RRIKYVRYADDFIIGVIGSKSDCEAIKEDIKNFlgeklkltlseektlitHGNRKAKFLG  360
            ++I+Y RYADDF+IGVIGSK D E IKED+K FL EKL L +SEEKT +TH+++  ++LG
Sbjct  300  KKIQYNRYADDFVIGVIGSKKDAEKIKEDVKIFLQEKLHLEMSEEKTKVTHSSKPVRYLG  359

Query  361  YEIYVRPFTDKTLRGEKSGVLIKA-YGKKVVLEVPMSTMRDKLLYYEAMEIHQFE--GKA  417
            Y++  + +  K ++  K+G + +  YG KV L +P      K +   A+++ + +  GK 
Sbjct  360  YDF--KVIHSKNMKRCKNGDMKRVWYG-KVFLYMPKEKWIKKAMERGAIQVKRNNDTGKE  416

Query  418  KWKPTSRTKLLHLDDLEILDAYNREIRGFANYFSIANNSSHLNSFKYIMQYSLYKTFARK  477
             W+P +R  L++  D EI+ ++N EIRG+ N++ IA+N + L+ + Y+++YS+ KT+A K
Sbjct  417  MWRPMPRKDLMNRSDAEIVSTFNSEIRGLYNFYRIAENVGALHKYYYMVRYSMLKTLAGK  476

Query  478  YSTTARKIIAKYRHHKDFAVFYEDKKGGKKMRVFFNGSFKRKTTAMDASCDYVANTIFNT  537
              T    I  +   +  + + Y+  K G+K   F++++F++ + + D   D +++     
Sbjct  477  HRTNVSVIKKRHMVNGVLRIPYDTTK-GRKYCEFYHDGFRKHSDGYDNVADVMPSYRKYD  535

Query  538  TVSSLIQRLKAG  549
            +  ++++R+KAG
Sbjct  536  SRHTIVNRIKAG  547

36) matR in NC_009004


> NC_021994_R1|7|G7|529233401|YP_008394213.1|Enterococcus_faecium_Aus0085|+|4653..6470|-|EFAU085_00689|HNH 
endonuclease domain 
protein
Length=605

 Score =  354 bits (1328),  Expect = 1e-98, Method: Compositional matrix adjust.
 Identities = 243/602 (41%), Positives = 388/602 (65%), Gaps = 20/602 (3%)

Query  1    MKPTMAILERISKNSQENIDEVFTRLYRYLLRPDIYYVAYQNLYSNKGASTKGILDDTAD  60
            M+  + +L  +  ++  + +  + RLYR L  P++Y +AY N+  ++G+ T+G+ ++T D
Sbjct  1    MRNPIHVLKSLEEKASVS-NYKYERLYRNLYNPEFYLLAYANIAKSQGSMTQGVDGQTLD  59

Query  61   GFSEEKIKKIIQSLKDGTYYPQPVRRMYIAKKNSKKMRPLGIPTFTDKLIQEAVRIILES  120
              S  +I++II+S+++ TY P+P +R YI+KKN+K +RPLGI +  DKL+QE VR+ILE+
Sbjct  60   NMSLPRINRIIESIRNRTYQPKPAKRKYIPKKNGK-LRPLGITSTDDKLVQEVVRMILEA  118

Query  121  IYEPVFEDVSHGFRPQRSCHTALKTIKREFGGARWFVEGDIKGCFDNIDHVTLIGLINLK  180
            IYEP F + SHGFRP+RSCHTAL  +K++F G  W+VEGDIK+CFDN+DH  L+ L+  +
Sbjct  119  IYEPTFSNNSHGFRPKRSCHTALTQVKKNFTGVTWIVEGDIKACFDNFDHHVLVELLRKR  178

Query  181  IKDMKMSQLIYKFLKAGYLENWQYHKTYSGTPQGGILSPLLANIYLHELDKFVLQLKMKF  240
            I D     LI KFLKAGY+E+WQY+ TYSG PQG+ +SP+ ANIYL ELD+++ + K K+
Sbjct  179  ISDEAFIGLIWKFLKAGYMEQWQYNCTYSGVPQGSGISPICANIYLSELDNYMQEYKEKY  238

Query  241  DRESPERITPEYRELHNEIKRISHRLKKLEGEEKAKVLL--EYQEKRKRLPTLPCTS---  295
            D E+  R T    E +   +R     K L G EK+   L  E+++ R++       +   
Sbjct  239  DCEPERRRTTR--EYERASRRYRKARKALMGAEKSTPELVKEFKDSRRKKMNQHYYNPFE  296

Query  296  QTNKVLKYVRYADDFIISVKGSKEDCQWIKEQLKLFIHNKLKMELSEEKTLITHSSQPAR  355
            +  K ++Y RYADDF+I+V GSK D + IKE++K+F+++KL +E+SEEKT +THSS+P R
Sbjct  297  EGFKKIQYNRYADDFVIGVIGSKKDAEKIKEDVKIFLQEKLHLEMSEEKTKVTHSSKPVR  356

Query  356  FLGYDIRVRRSGTIKRSGKVK-KRTLNGSVELLIPLQDKIRQFIFDKKIAIQKKDSS---  411
            +LGYD++V +S  +KR  +   KR   G V L +P +  I++ +    I +++++ +   
Sbjct  357  YLGYDFKVIHSKNMKRCKNGDMKRVWYGKVFLYMPKEKWIKKAMERGAIQVKRNNDTGKE  416

Query  412  -WFPVHRKYLIRSTDLEIITIYNSELRGICNYYGLASNFNQLNYFAYLMEYSCLKTIASK  470
             W P+ RK L+  +D EI++ +NSE+RG+ N+Y +A N   L+ + Y++ YS LKT+A+K
Sbjct  417  MWRPMPRKDLMNRSDAEIVSTFNSEIRGLYNFYRIAENVGALHKYYYMVRYSMLKTLAGK  476

Query  471  HKGTLSKTISMFKDGSGSWGIPYEIKQGKQ--RRYFANFSECKSPYQFTDEISQAPVLYG  528
            H+  +S  I      +G   IPY+  +G++    Y   F      Y+   ++  +   Y+
Sbjct  477  HRTNVS-VIKKRHMVNGVLRIPYDTTKGRKYCEFYHDGFRKHSDGYDNVADVMPSYRKYD  535

Query  529  YARNTLENRLKAKCCELCGTSDENTSYEIHHVNKVKNLKGKEKWEMAMIAKQRKTLVVCF  588
             +R+T+ NR+KA  CE+CG   +     +HHV  +K+LKG++  E  M+  +RK+L +C 
Sbjct  536  -SRHTIVNRIKAGVCEICGEHADYLC--MHHVRTLKSLKGRDIFEQKMLKMRRKSLALCP  592

Query  589  HC  590
            +C
Sbjct  593  DC  594

37) LLNZ_07090 in NC_017949


> NC_021994_R1|7|G7|529233401|YP_008394213.1|Enterococcus_faecium_Aus0085|+|4653..6470|-|EFAU085_00689|HNH 
endonuclease domain 
protein
Length=605

 Score =  354 bits (1328),  Expect = 1e-98, Method: Compositional matrix adjust.
 Identities = 243/602 (41%), Positives = 388/602 (65%), Gaps = 20/602 (3%)

Query  1    MKPTMAILERISKNSQENIDEVFTRLYRYLLRPDIYYVAYQNLYSNKGASTKGILDDTAD  60
            M+  + +L  +  ++  + +  + RLYR L  P++Y +AY N+  ++G+ T+G+ ++T D
Sbjct  1    MRNPIHVLKSLEEKASVS-NYKYERLYRNLYNPEFYLLAYANIAKSQGSMTQGVDGQTLD  59

Query  61   GFSEEKIKKIIQSLKDGTYYPQPVRRMYIAKKNSKKMRPLGIPTFTDKLIQEAVRIILES  120
              S  +I++II+S+++ TY P+P +R YI+KKN+K +RPLGI +  DKL+QE VR+ILE+
Sbjct  60   NMSLPRINRIIESIRNRTYQPKPAKRKYIPKKNGK-LRPLGITSTDDKLVQEVVRMILEA  118

Query  121  IYEPVFEDVSHGFRPQRSCHTALKTIKREFGGARWFVEGDIKGCFDNIDHVTLIGLINLK  180
            IYEP F + SHGFRP+RSCHTAL  +K++F G  W+VEGDIK+CFDN+DH  L+ L+  +
Sbjct  119  IYEPTFSNNSHGFRPKRSCHTALTQVKKNFTGVTWIVEGDIKACFDNFDHHVLVELLRKR  178

Query  181  IKDMKMSQLIYKFLKAGYLENWQYHKTYSGTPQGGILSPLLANIYLHELDKFVLQLKMKF  240
            I D     LI KFLKAGY+E+WQY+ TYSG PQG+ +SP+ ANIYL ELD+++ + K K+
Sbjct  179  ISDEAFIGLIWKFLKAGYMEQWQYNCTYSGVPQGSGISPICANIYLSELDNYMQEYKEKY  238

Query  241  DRESPERITPEYRELHNEIKRISHRLKKLEGEEKAKVLL--EYQEKRKRLPTLPCTS---  295
            D E+  R T    E +   +R     K L G EK+   L  E+++ R++       +   
Sbjct  239  DCEPERRRTTR--EYERASRRYRKARKALMGAEKSTPELVKEFKDSRRKKMNQHYYNPFE  296

Query  296  QTNKVLKYVRYADDFIISVKGSKEDCQWIKEQLKLFIHNKLKMELSEEKTLITHSSQPAR  355
            +  K ++Y RYADDF+I+V GSK D + IKE++K+F+++KL +E+SEEKT +THSS+P R
Sbjct  297  EGFKKIQYNRYADDFVIGVIGSKKDAEKIKEDVKIFLQEKLHLEMSEEKTKVTHSSKPVR  356

Query  356  FLGYDIRVRRSGTIKRSGKVK-KRTLNGSVELLIPLQDKIRQFIFDKKIAIQKKDSS---  411
            +LGYD++V +S  +KR  +   KR   G V L +P +  I++ +    I +++++ +   
Sbjct  357  YLGYDFKVIHSKNMKRCKNGDMKRVWYGKVFLYMPKEKWIKKAMERGAIQVKRNNDTGKE  416

Query  412  -WFPVHRKYLIRSTDLEIITIYNSELRGICNYYGLASNFNQLNYFAYLMEYSCLKTIASK  470
             W P+ RK L+  +D EI++ +NSE+RG+ N+Y +A N   L+ + Y++ YS LKT+A+K
Sbjct  417  MWRPMPRKDLMNRSDAEIVSTFNSEIRGLYNFYRIAENVGALHKYYYMVRYSMLKTLAGK  476

Query  471  HKGTLSKTISMFKDGSGSWGIPYEIKQGKQ--RRYFANFSECKSPYQFTDEISQAPVLYG  528
            H+  +S  I      +G   IPY+  +G++    Y   F      Y+   ++  +   Y+
Sbjct  477  HRTNVS-VIKKRHMVNGVLRIPYDTTKGRKYCEFYHDGFRKHSDGYDNVADVMPSYRKYD  535

Query  529  YARNTLENRLKAKCCELCGTSDENTSYEIHHVNKVKNLKGKEKWEMAMIAKQRKTLVVCF  588
             +R+T+ NR+KA  CE+CG   +     +HHV  +K+LKG++  E  M+  +RK+L +C 
Sbjct  536  -SRHTIVNRIKAGVCEICGEHADYLC--MHHVRTLKSLKGRDIFEQKMLKMRRKSLALCP  592

Query  589  HC  590
            +C
Sbjct  593  DC  594

38) LACR_C19 in NC_008505


> NC_021994_R1|7|G7|529233401|YP_008394213.1|Enterococcus_faecium_Aus0085|+|4653..6470|-|EFAU085_00689|HNH 
endonuclease domain 
protein
Length=605

 Score =  353 bits (1324),  Expect = 3e-98, Method: Compositional matrix adjust.
 Identities = 242/602 (41%), Positives = 387/602 (65%), Gaps = 20/602 (3%)

Query  1    MKPTMAILERISKNSQENIDEVFTRLYRYLLRPDIYYVAYQNLYSNKGASTKGILDDTAD  60
            M+  + +L  +  ++  + +  + RLYR L  P++Y +AY N+  ++G+ T+G+ ++T D
Sbjct  1    MRNPIHVLKSLEEKASVS-NYKYERLYRNLYNPEFYLLAYANIAKSQGSMTQGVDGQTLD  59

Query  61   GFSEEKIKKIIQSLKDGTYYPQPVRRMYIAKKNSKKMRPLGIPTFTDKLIQEAVRIILES  120
              S  +I++II+S+++ TY P+P +R YI+KKN+K +RPLGI +  DKL+QE VR+ILE+
Sbjct  60   NMSLPRINRIIESIRNRTYQPKPAKRKYIPKKNGK-LRPLGITSTDDKLVQEVVRMILEA  118

Query  121  IYEPVFEDVSHGFRPQRSCHTALKTIKREFGGARWFVEGDIKGCFDNIDHVTLIGLINLK  180
            IYEP F + SHGFRP+RSCHTAL  +K++F G  W+VEGDIK+CFDN+DH  L+ L+  +
Sbjct  119  IYEPTFSNNSHGFRPKRSCHTALTQVKKNFTGVTWIVEGDIKACFDNFDHHVLVELLRKR  178

Query  181  IKDMKMSQLIYKFLKAGYLENWQYHKTYSGTPQGGILSPLLANIYLHELDKFVLQLKMKF  240
            I D     LI KFLKAGY+E+WQY+ TYSG PQG+ +SP+ ANIYL ELD+++ + K K+
Sbjct  179  ISDEAFIGLIWKFLKAGYMEQWQYNCTYSGVPQGSGISPICANIYLSELDNYMQEYKEKY  238

Query  241  DRESPERITPEYRELHNEIKRISHRLKKLEGEEKAKVLL--EYQEKRKRLPTLPCTS---  295
            D E+  R T    E +   +R     K L G EK+   L  E+++ R++       +   
Sbjct  239  DCEPERRRTTR--EYERASRRYRKARKALMGAEKSTPELVKEFKDSRRKKMNQHYYNPFE  296

Query  296  QTNKVLKYVRYADDFIISVKGSKEDCQWIKEQLKLFIHNKLKMEFSEEKTLITHSSQPAR  355
            +  K ++Y RYADDF+I+V GSK D + IKE++K+F+++KL +E SEEKT +THSS+P R
Sbjct  297  EGFKKIQYNRYADDFVIGVIGSKKDAEKIKEDVKIFLQEKLHLEMSEEKTKVTHSSKPVR  356

Query  356  FLGYDIRVRRSGTIKRSGKV-KKRTLNGSVELFIPLQDKIRQFIFDKKIAIQKKDSS---  411
            +LGYD++V +S  +KR  +   KR   G V L++P +  I++ +    I +++++ +   
Sbjct  357  YLGYDFKVIHSKNMKRCKNGDMKRVWYGKVFLYMPKEKWIKKAMERGAIQVKRNNDTGKE  416

Query  412  -WFPVHRKYLIRSTDLEIITIYNSELRGICNYYGLASNFNQLNYFAYLMEYNCLKTIASK  470
             W P+ RK L+  +D EI++ +NSE+RG+ N+Y +A N   L+ + Y++ Y+ LKT+A+K
Sbjct  417  MWRPMPRKDLMNRSDAEIVSTFNSEIRGLYNFYRIAENVGALHKYYYMVRYSMLKTLAGK  476

Query  471  HKGTLSKTISMFKDGSGSWGIPYEIKQGKQ--RRYFANFSECKSPYQFTDKISQAPVLYG  528
            H+  +S  I      +G   IPY+  +G++    Y   F      Y+    +  +   Y+
Sbjct  477  HRTNVS-VIKKRHMVNGVLRIPYDTTKGRKYCEFYHDGFRKHSDGYDNVADVMPSYRKYD  535

Query  529  YARNTLENRLKAKCCELCGTSDENTSYEIHHVNKVKNLKGKEKWEMAMIAKQRKTLVVCF  588
             +R+T+ NR+KA  CE+CG   +     +HHV  +K+LKG++  E  M+  +RK+L +C 
Sbjct  536  -SRHTIVNRIKAGVCEICGEHADYLC--MHHVRTLKSLKGRDIFEQKMLKMRRKSLALCP  592

Query  589  HC  590
            +C
Sbjct  593  DC  594

39) llh_13615 in NC_017496


> NC_021994_R1|7|G7|529233401|YP_008394213.1|Enterococcus_faecium_Aus0085|+|4653..6470|-|EFAU085_00689|HNH 
endonuclease domain 
protein
Length=605

 Score =  352 bits (1322),  Expect = 4e-98, Method: Compositional matrix adjust.
 Identities = 243/602 (41%), Positives = 387/602 (65%), Gaps = 20/602 (3%)

Query  1    MKPTMAILERISKNSQENIDEVFTRLYRYLLRPDIYYVAYQNLYSNKGASTKGILDDTAD  60
            M+  + +L  +  ++  + +  + RLYR L  P++Y +AY N+  ++G+ T+G+ ++T D
Sbjct  1    MRNPIHVLKSLEEKASVS-NYKYERLYRNLYNPEFYLLAYANIAKSQGSMTQGVDGQTLD  59

Query  61   GFSEEKIKKIIQSLKDGTYYPQPVRRMYIAKKNSKKMRPLGIPTFTDKLIQEAVRIILES  120
              S  +I++II+S+++ TY P+P +R YI+KKN+K +RPLGI +  DKL+QE VR+ILE+
Sbjct  60   NMSLPRINRIIESIRNRTYQPKPAKRKYIPKKNGK-LRPLGITSTDDKLVQEVVRMILEA  118

Query  121  IYEPVFEDVSHGFRPQRSCHTALKTIKREFGGARWFVEGDIKGCFDNIDHVTLIGLINLK  180
            IYEP F + SHGFRP+RSCHTAL  +K++F G  W+VEGDIK+CFDN+DH  L+ L+  +
Sbjct  119  IYEPTFSNNSHGFRPKRSCHTALTQVKKNFTGVTWIVEGDIKACFDNFDHHVLVELLRKR  178

Query  181  IKDMKMSQLIYKFLKAGYLENWQYHKTYSGTPQGGILSPLLANIYLHELDKFVLQLKMKF  240
            I D     LI KFLKAGY+E+WQY+ TYSG PQG+ +SP+ ANIYL ELD+++ + K K+
Sbjct  179  ISDEAFIGLIWKFLKAGYMEQWQYNCTYSGVPQGSGISPICANIYLSELDNYMQEYKEKY  238

Query  241  DRESPERITPEYRELHNEIKRISHRLKKLEGEEKAKVLL--EYQEKRKRLPTLPCTS---  295
            D E+  R T    E +   +R     K L G EK+   L  E+++ R++       +   
Sbjct  239  DCEPERRRTTR--EYERASRRYRKARKALMGAEKSTPELVKEFKDSRRKKMNQHYYNPFE  296

Query  296  QTNKVLKYVRYADDFIISVKGSKEDCQWIKEQLKLFIHNKLKMELSEEKTLITHSSQPAR  355
            +  K ++Y RYADDF+I+V GSK D + IKE++K+F+++KL +E+SEEKT +THSS+P R
Sbjct  297  EGFKKIQYNRYADDFVIGVIGSKKDAEKIKEDVKIFLQEKLHLEMSEEKTKVTHSSKPVR  356

Query  356  FLGYDIRVRRSGTIKRSGKVK-KRTLNGSVELLIPLQDKIRQFIFDKKIAIQKKDSS---  411
            +LGYD++V +S  +KR  +   KR   G V L +P +  I++ +    I +++++ +   
Sbjct  357  YLGYDFKVIHSKNMKRCKNGDMKRVWYGKVFLYMPKEKWIKKAMERGAIQVKRNNDTGKE  416

Query  412  -WFPVHRKYLIRSTDLEIITIYNSELRGICNYYGLASNFNQLNYFAYLMEYSCLKTIASK  470
             W P+ RK L+  +D EI++ +NSE+RG+ N+Y +A N   L+ + Y++ YS LKT+A+K
Sbjct  417  MWRPMPRKDLMNRSDAEIVSTFNSEIRGLYNFYRIAENVGALHKYYYMVRYSMLKTLAGK  476

Query  471  HKGTLSKTISMFKDGSGSWGIPYEIKQGKQ--RRYFANFSECKSPYQFTDKISQAPVLYG  528
            H+  +S  I      +G   IPY+  +G++    Y   F      Y+    +  +   Y+
Sbjct  477  HRTNVS-VIKKRHMVNGVLRIPYDTTKGRKYCEFYHDGFRKHSDGYDNVADVMPSYRKYD  535

Query  529  YARNTLENRLKAKCCELCGTSDENTSYEIHHVNKVKNLKGKEKWEMAMIAKQRKTLVVCF  588
             +R+T+ NR+KA  CE+CG   +     +HHV  +K+LKG++  E  M+  +RK+L +C 
Sbjct  536  -SRHTIVNRIKAGVCEICGEHADYLC--MHHVRTLKSLKGRDIFEQKMLKMRRKSLALCP  592

Query  589  HC  590
            +C
Sbjct  593  DC  594

40) LACR_1685 in NC_008527


> NC_021994_R1|7|G7|529233401|YP_008394213.1|Enterococcus_faecium_Aus0085|+|4653..6470|-|EFAU085_00689|HNH 
endonuclease domain 
protein
Length=605

 Score =  352 bits (1322),  Expect = 4e-98, Method: Compositional matrix adjust.
 Identities = 243/602 (41%), Positives = 387/602 (65%), Gaps = 20/602 (3%)

Query  1    MKPTMAILERISKNSQENIDEVFTRLYRYLLRPDIYYVAYQNLYSNKGASTKGILDDTAD  60
            M+  + +L  +  ++  + +  + RLYR L  P++Y +AY N+  ++G+ T+G+ ++T D
Sbjct  1    MRNPIHVLKSLEEKASVS-NYKYERLYRNLYNPEFYLLAYANIAKSQGSMTQGVDGQTLD  59

Query  61   GFSEEKIKKIIQSLKDGTYYPQPVRRMYIAKKNSKKMRPLGIPTFTDKLIQEAVRIILES  120
              S  +I++II+S+++ TY P+P +R YI+KKN+K +RPLGI +  DKL+QE VR+ILE+
Sbjct  60   NMSLPRINRIIESIRNRTYQPKPAKRKYIPKKNGK-LRPLGITSTDDKLVQEVVRMILEA  118

Query  121  IYEPVFEDVSHGFRPQRSCHTALKTIKREFGGARWFVEGDIKGCFDNIDHVTLIGLINLK  180
            IYEP F + SHGFRP+RSCHTAL  +K++F G  W+VEGDIK+CFDN+DH  L+ L+  +
Sbjct  119  IYEPTFSNNSHGFRPKRSCHTALTQVKKNFTGVTWIVEGDIKACFDNFDHHVLVELLRKR  178

Query  181  IKDMKMSQLIYKFLKAGYLENWQYHKTYSGTPQGGILSPLLANIYLHELDKFVLQLKMKF  240
            I D     LI KFLKAGY+E+WQY+ TYSG PQG+ +SP+ ANIYL ELD+++ + K K+
Sbjct  179  ISDEAFIGLIWKFLKAGYMEQWQYNCTYSGVPQGSGISPICANIYLSELDNYMQEYKEKY  238

Query  241  DRESPERITPEYRELHNEIKRISHRLKKLEGEEKAKVLL--EYQEKRKRLPTLPCTS---  295
            D E+  R T    E +   +R     K L G EK+   L  E+++ R++       +   
Sbjct  239  DCEPERRRTTR--EYERASRRYRKARKALMGAEKSTPELVKEFKDSRRKKMNQHYYNPFE  296

Query  296  QTNKVLKYVRYADDFIISVKGSKEDCQWIKEQLKLFIHNKLKMELSEEKTLITHSSQPAR  355
            +  K ++Y RYADDF+I+V GSK D + IKE++K+F+++KL +E+SEEKT +THSS+P R
Sbjct  297  EGFKKIQYNRYADDFVIGVIGSKKDAEKIKEDVKIFLQEKLHLEMSEEKTKVTHSSKPVR  356

Query  356  FLGYDIRVRRSGTIKRSGKVK-KRTLNGSVELLIPLQDKIRQFIFDKKIAIQKKDSS---  411
            +LGYD++V +S  +KR  +   KR   G V L +P +  I++ +    I +++++ +   
Sbjct  357  YLGYDFKVIHSKNMKRCKNGDMKRVWYGKVFLYMPKEKWIKKAMERGAIQVKRNNDTGKE  416

Query  412  -WFPVHRKYLIRSTDLEIITIYNSELRGICNYYGLASNFNQLNYFAYLMEYSCLKTIASK  470
             W P+ RK L+  +D EI++ +NSE+RG+ N+Y +A N   L+ + Y++ YS LKT+A+K
Sbjct  417  MWRPMPRKDLMNRSDAEIVSTFNSEIRGLYNFYRIAENVGALHKYYYMVRYSMLKTLAGK  476

Query  471  HKGTLSKTISMFKDGSGSWGIPYEIKQGKQ--RRYFANFSECKSPYQFTDKISQAPVLYG  528
            H+  +S  I      +G   IPY+  +G++    Y   F      Y+    +  +   Y+
Sbjct  477  HRTNVS-VIKKRHMVNGVLRIPYDTTKGRKYCEFYHDGFRKHSDGYDNVADVMPSYRKYD  535

Query  529  YARNTLENRLKAKCCELCGTSDENTSYEIHHVNKVKNLKGKEKWEMAMIAKQRKTLVVCF  588
             +R+T+ NR+KA  CE+CG   +     +HHV  +K+LKG++  E  M+  +RK+L +C 
Sbjct  536  -SRHTIVNRIKAGVCEICGEHADYLC--MHHVRTLKSLKGRDIFEQKMLKMRRKSLALCP  592

Query  589  HC  590
            +C
Sbjct  593  DC  594

41) AL1_27550 in NC_021030


> NC_021994_R1|7|G7|529233401|YP_008394213.1|Enterococcus_faecium_Aus0085|+|4653..6470|-|EFAU085_00689|HNH 
endonuclease domain 
protein
Length=605

 Score =  351 bits (1317),  Expect = 8e-98, Method: Compositional matrix adjust.
 Identities = 219/491 (45%), Positives = 326/491 (67%), Gaps = 7/491 (1%)

Query  1    MVLEAIYEGHFEDTSHGFRPHRSCHTALNAVQKTFTGKKWFIEGDIKGFFDNVNHDILID  60
            M+LEAIYE  F + SHGFRP RSCHTAL  V+K FTG  W++EGDIK+ FDN +H++L++
Sbjct  114  MILEAIYEPTFSNNSHGFRPKRSCHTALTQVKKNFTGVTWIVEGDIKACFDNFDHHVLVE  173

Query  61   ILKERISDERFIRLIRKFLKAGYLEQWQFHGTYSGMPQGGIISPILANIYLDKLDKYMKE  120
            +L+ RISDE FI LI+KFLKAGY+EQWQ++ TYSG+PQG+ ISPI ANIYL  LD+YM+E
Sbjct  174  LLRKRISDEAFIGLIWKFLKAGYMEQWQYNCTYSGVPQGSGISPICANIYLSELDNYMQE  233

Query  121  YASKFDKGDRGRQQREYEVLTYQK-RLVMRELKTATNNVERKVLVNRLKEIDKTRSAMPC  179
            Y  K+D     R+       + ++ R   + L  A ++     LV+ +K+  + +     
Sbjct  234  YKEKYDCEPERRRTTREYERASRRYRKARKALMGAEKSTPE--LVKEFKDSRRKKMNQHY  291

Query  180  FAPMDGNFKRLKYVRYADDFLIGIIGSKEDAVKIKDDIKRFLADRLALELSDEKTLITHT  239
            + P +  FK+++Y RYADDF+IG+IGSK DA KIK+D+K FL ++L LE+S+EKT +TH+
Sbjct  292  YNPFEEGFKKIQYNRYADDFVIGVIGSKKDAEKIKEDVKIFLQEKLHLEMSEEKTKVTHS  351

Query  240  EKPAKFLGYEVTVRRSNLQKRNKRGSLSRVYGNKVRLKVTTEVIKKKLLELCVLKF--SY  297
             KP ++LGY+  V +S+  KR K G + RV   KV L +  E   KK +E   ++   + 
Sbjct  352  SKPVRYLGYDFKVIHSKNMKRCKNGDMKRVWYGKVFLYMPKEKWIKKAMERGAIQVKRNN  411

Query  298  HNGHEQWIPKHRSELINNDDLEILDSYNAEIRGFYNYYSIANNASELNTFHYIMQYSMYK  357
            + G E W P  R +L+N  D EI+ ++N+EIRG+YN+Y IA+N + L+ + Y+++YSM K
Sbjct  412  DTGKEMWRPMPRKDLMNRSDAEIVSTFNSEIRGLYNFYRIAENVGALHKYYYMVRYSMLK  471

Query  358  TFAGKYRTTVRRICRKYKRNGVFTVGYTVKNGQVKERRLYNEGFKRKRPSYDRSIDRCPN  417
            T+AGK RT V  I ++   NGV+ + Y   +G+ K   +Y++GF++   +YD   D  P+
Sbjct  472  TLAGKHRTNVSVIKKRHMVNGVLRIPYDTTKGR-KYCEFYHDGFRKHSDGYDNVADVMPS  530

Query  418  PMPGVSTTSLIDRLKARKCELCGA-TDNLVMHHVRKLGELKGKENWEKLMIARRRKAMAV  476
                 S  ++++R+KA  CE+CG  +D L MHHVR L  LKG++  E+ M+  RRK++A+
Sbjct  531  YRKYDSRHTIVNRIKAGVCEICGEHADYLCMHHVRTLKSLKGRDIFEQKMLKMRRKSLAL  590

Query  477  CGSCHQKIHHG  487
            C  C + +H+ 
Sbjct  591  CPDCFELLHET  601

42) SeseC_01322 in NC_017582


> NC_021994_R1|7|G7|529233401|YP_008394213.1|Enterococcus_faecium_Aus0085|+|4653..6470|-|EFAU085_00689|HNH 
endonuclease domain 
protein
Length=605

 Score =  347 bits (1302),  Expect = 2e-96, Method: Compositional matrix adjust.
 Identities = 244/602 (41%), Positives = 393/602 (66%), Gaps = 30/602 (4%)

Query  1    MKPTMAILERISKNSMEQKDEV----FTRLYRYLLRPDIYYIAYQNLYSNKGAGTKGIDD  56
            M+  + +L     +S+E+K  V    + RLYR L  P++Y +AY N+  ++G+ T+G+D+
Sbjct  1    MRNPIHVL-----KSLEEKASVSNYKYERLYRNLYNPEFYLLAYANIAKSQGSMTQGVDG  55

Query  57   DTADGFSEKKISTIINSLASESYTPKPVRRTYISKKSSSKLRPLGLPTFTDKLIQEVLRL  116
            +T D  S  +I+ II+S+ + +Y PKP +R YI+KK++ KLRPLG+ +  DKL+QEV+R+
Sbjct  56   QTLDNMSLPRINRIIESIRNRTYQPKPAKRKYIPKKNG-KLRPLGITSTDDKLVQEVVRM  114

Query  117  ILEAIYEPIFLDTSHGFRPKRSCHTALKMIKREFGGARWFVEGDIKGCFDNIDHQVLISI  176
            ILEAIYEP F + SHGFRPKRSCHTAL  +K++F G  W+VEGDIK+CFDN+DH+VL+ +
Sbjct  115  ILEAIYEPTFSNNSHGFRPKRSCHTALTQVKKNFTGVTWIVEGDIKACFDNFDHHVLVEL  174

Query  177  IQKKVKDARFIKLIYKFLKAGYMENWNYHKTYSGTPQGGILSPLLANIYLHELDLFVLKL  236
            ++K++ D  FI LI KFLKAGYME+W+Y+ TYSG PQG+ +SP+ ANIYL ELD ++   
Sbjct  175  LRKRISDEAFIGLIWKFLKAGYMEQWQYNCTYSGVPQGSGISPICANIYLSELDNYMQEY  234

Query  237  KEQFD-NPQKDNITSEYRQAHNELKRLSNRLKKVEGNEKQELLEEYLIKRQRLMTIPCTA  295
            KE++D +P++   T EY +A    ++  + L   E +   EL+ E+   R++ M      
Sbjct  235  KEKYDCEPERRRTTREYERASRRYRKARKALMGAE-KSTPELVKEFKDSRRKKMNQHYYN  293

Query  296  QTD---KKLKYVRYADDFIISVKGNKKDCHWLKQQLADFINGHLKMTLSPEKTLITHSSN  352
              +   KK++Y RYADDF+I+V G+KKD + +K+++  F++  L + +S EKT +THSS+
Sbjct  294  PFEEGFKKIQYNRYADDFVIGVIGSKKDAEKIKEDVKIFLQEKLHLEMSEEKTKVTHSSK  353

Query  353  CARFLGYDIRVRRSQAIKRGGSGQVKKRTLNGSVELLIPFKDKIHLFLFNKGIVIQKNDG  412
              R+LGYD++V +S+ +KR  +G++ KR   G V L +P    I   +   +I +++N++
Sbjct  354  PVRYLGYDFKVIHSKNMKRCKNGDM-KRVWYGKVFLYMPKEKWIKKAMERGAIQVKRNND  412

Query  413  S----YFPVHRKNILTATDLEIVTIYNSELRGICRYYGLTSNFNQLNYFAYLMEYSCLKT  468
            +      P+ RK+++  +D EIV+ +NSE+RG+  +Y ++ N   L+ + Y++ YS LKT
Sbjct  413  TGKEMWRPMPRKDLMNRSDAEIVSTFNSEIRGLYNFYRIAENVGALHKYYYMVRYSMLKT  472

Query  469  LASKHKTSLVKIRAKYKDGFGSWAIPYETKTTKK--RMYFTDYTKCKSPSTFTDLKSSVA  526
            LA+KH+T++  I+ +     G   IPY+T   +K    Y  ++   K +  + ++   ++
Sbjct  473  LAGKHRTNVSVIKKRHMVN-GVLRIPYDTTKGRKYCEFYHDGFR--KHSDGYDNVADVMP  529

Query  527  VTYGY-SRTTFESRLKAKKCELCGTTDKQTTYE-IHHVNKGKNLKGKEKWEQMMIAKQRK  584
                Y SR T+ +R+KA  CE+CG    ++ Y  +HHV   K+LKG++  EQ M+  +RK
Sbjct  530  SYRKYDSRHTIVNRIKAGVCEICGE---HADYLCMHHVRTLKSLKGRDIFEQKMLKMRRK  586

Query  585  TL  586
            +L
Sbjct  587  SL  588

43) Bcer98_3169 in NC_009674


> NC_021994_R1|7|G7|529233401|YP_008394213.1|Enterococcus_faecium_Aus0085|+|4653..6470|-|EFAU085_00689|HNH 
endonuclease domain 
protein
Length=605

 Score =  276 bits (1033),  Expect = 2e-75, Method: Compositional matrix adjust.
 Identities = 187/465 (41%), Positives = 304/465 (66%), Gaps = 20/465 (4%)

Query  26   YRLMYKRELWIKAYVKLYPNAGNLTKGTSEETIDGFYLQKIDEIIDQLKKGMFRFAPVRR  85
            YR +Y+ E+ + AY ++  + G++T+G   +T+D   L +I+ II+ +++  ++  P +R
Sbjct  26   YRNLYNPEFYLLAYANIAKSQGSMTQGVDGQTLDNMSLPRINRIIESIRNRTYQPKPAKR  85

Query  86   AYISKANGKKRPLGVPNFKDKLVQEVMRMILENVYEPTFSDNSHGFREGRSCHTALSQIK  145
             YI+K NGK RPLG+ +  DKLVQEV+RMILE +YEPTFS+NSHGFR  RSCHTAL+Q+K
Sbjct  86   KYIPKKNGKLRPLGITSTDDKLVQEVVRMILEAIYEPTFSNNSHGFRPKRSCHTALTQVK  145

Query  146  NTWKGLTWCIEGAIKGFFDHIDHSVLINLISKRMNDHRFLLLIHNALASGVMENWTYQKT  205
            +   G+TW +EG IK+ FD++DH VL++L+ KR++D+ F+ LI + L +G ME+W Y+ T
Sbjct  146  KNFTGVTWIVEGDIKACFDNFDHHVLVELLRKRISDEAFIGLIWKFLKAGYMEQWQYNCT  205

Query  206  YSGTPQGGILSPLLANIYLHEFDIFLEKQIEKFDKEKLRARNKEYTKIHSEIRSLSRKVK  265
            YSG PQG+ +SP+ ANIYL E+D +++   EK+D E  R R       +   R   +  K
Sbjct  206  YSGVPQGSGISPICANIYLSELDNYMQEYKEKYDCEPERRRTT--REYERASRRYRKARK  263

Query  266  SLDDRTGHRLWKGREKVIETIAELKRKQIGISSVNPMDNDYQKMKYVRYADDFVIGIAGS  325
            +L +       K+   ++  + + +RK++     NP +++++K++Y RYADDFVIG+ GS
Sbjct  264  ALMGAE-----KSTPELVKEFKDSRRKKMNQHYYNPFEEGFKKIQYNRYADDFVIGVIGS  318

Query  326  KDCAVNIKETIKNFLKQELHLELSEEKTLINHLENPISFLGYEFR--KWNEIKRTRVLYK  383
            K  A +IKE +K FL++ LHLE+SEEKT + H  +P+ +LGY+F+    +++KR +   +
Sbjct  319  KKDAEKIKEDVKIFLQEKLHLEMSEEKTKVTHSSKPVRYLGYDFKVIHSKNMKRCK---N  375

Query  384  NHKQRALSRAIKLEIPKKK-----MKEFAI---KNGYGNLDNFKSIHRAKLLNNSELEIL  435
             + +R     + L +PK K     M   AI   +N     +  +++ R  L+N S+ EI+
Sbjct  376  GDMKRVWYGKVFLYMPKEKWIKKAMERGAIQVKRNNDTGKEMWRPMPRKDLMNRSDAEIV  435

Query  436  CTYNAELRGIANYYKLANNYHHLDKLFYLAESSFIKTIANKRRST  480
             T+N+E+RG+ N+Y++A+N   L+K +Y+   S +KT+A K+R+ 
Sbjct  436  STFNSEIRGLYNFYRIAENVGALHKYYYMVRYSMLKTLAGKHRTN  480