> NC_016808_R1|63|G56|378773985|YP_005176228.1|Pasteurella_multocida_36950|-|54272..56323|topB1|Pmu_03290|DNA 
topoisomerase 
III
Length=683

 Score = 1038 bits (3934),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 630/683 (93%), Positives = 670/683 (99%), Gaps = 0/683 (0%)

Query  1    MKLFICEKPSQARDLASVLGATSKGDGLLATNDKSIIVTWGFGHLVEQYQPEDYDEVWKR  60
            MKLFICEKPSQARDLA+VLGATSKG+GLLAT DKSIIVTWGFGHLVEQYQPEDYDE WKR
Sbjct  1    MKLFICEKPSQARDLAGVLGATSKGEGLLATADKSIIVTWGFGHLVEQYQPEDYDEAWKR  60

Query  61   WAFETLPIIPAQWKMAPKKESKKQYNVVIGLIKKASLVVIATDADREGEMIARELLDLAG  120
            WAFETLPIIPAQWKM+PKKESKKQY+VVIGLIKKA+ VVIATDADREGEMIARELLDLAG
Sbjct  61   WAFETLPIIPAQWKMTPKKESKKQYSVVIGLIKKATSVVIATDADREGEMIARELLDLAG  120

Query  121  YRGQIQRCWLSALDDASIRKALQTLKSGKETEALYYAGMGRSRSDWLIGMNFSRLFTLMA  180
            YRGQIQRCWLSALDDASIRKALQTLKSGKETEALYYAGMGRSRSDWLIGMNFSRLFTLMA
Sbjct  121  YRGQIQRCWLSALDDASIRKALQTLKSGKETEALYYAGMGRSRSDWLIGMNFSRLFTLMA  180

Query  181  QAKGYSGKPLSVGRVQSPTLALVVNRDREIANFVPKAHYSLAVQLATASDETFVAGLSIP  240
            QAKGYSGKPLSVGRVQSPTL+LVVNRDREIANFVPK+HY+LAVQL+T+S+ETFVAGL++P
Sbjct  181  QAKGYSGKPLSVGRVQSPTLTLVVNRDREIANFVPKSHYALAVQLTTTSGETFVAGLAVP  240

Query  241  EQYLDESGLCLDSRVIQQAEAQIKQVGIAKVITVETKREKKAPPLLYALSDLQGECNRLF  300
            EQYLDESGLCLDSRVIQQAEAQIKQ G+AKV+TVETKREKK+PPLLYALSDLQGECNRLF
Sbjct  241  EQYLDESGLCLDSRVIQQAEAQIKQTGLAKVVTVETKREKKSPPLLYALSDLQGECNRLF  300

Query  301  GFGAQQVLDIAQSLYEEHKITTYPRTDCGYLPESQLTEVPMVIRSLVAADSELQTLLPRL  360
            GFGAQQVLDIAQSLYEEHKITTYPRTDCGYLPESQ+++VP VIRSLVA+DS LQTLLP+L
Sbjct  301  GFGAQQVLDIAQSLYEEHKITTYPRTDCGYLPESQFSDVPNVIRSLVASDSGLQTLLPKL  360

Query  361  NLQQKSRAWDDKKITAHHGIIPTIKKADLSKLSEEEMKVYDLIRRRYLAQFLPHLETDKT  420
            NL+QKSRAWDDKKITAHHGIIPTIKKADLSKLSEEEMKVYDLIRRRYLAQFLPHLE DKT
Sbjct  361  NLRQKSRAWDDKKITAHHGIIPTIKKADLSKLSEEEMKVYDLIRRRYLAQFLPHLEMDKT  420

Query  421  IATLQSSGHTLIARGNVIVSQGWRILFGKNADEDVGSDDEKQGLPALTANQQCRVTHSEV  480
            +ATLQSSGHTL+ARGNVIV+QGWRILFGKN DE+ G+DDEKQGLP LT NQQC VTHSEV
Sbjct  421  VATLQSSGHTLVARGNVIVAQGWRILFGKNVDEETGNDDEKQGLPVLTKNQQCNVTHSEV  480

Query  481  RTLQTKPPAHYTEGTLLEAMKNAARFVTDPRLKQRLRETEGLGTEATRAGLIQGLIDKGF  540
            RTLQTKPPAHYTEGTLL+AMKNAARFVTDPRLKQRLRETEGLGTEATRAGLIQGLIDKGF
Sbjct  481  RTLQTKPPAHYTEGTLLDAMKNAARFVTDPRLKQRLRETEGLGTEATRAGLIQGLIDKGF  540

Query  541  LIKKKKSLMASAEAIALIDSLPDLLKNPGLTALWEQALNQIAEGSMTLDDFMQRQETFVR  600
            L+KKKKSL+ASAEA+ALIDSLPDLLKNPGLTALWEQALNQIAEGSMTLD FMQ+QE+FV+
Sbjct  541  LLKKKKSLVASAEAVALIDSLPDLLKNPGLTALWEQALNQIAEGSMTLDAFMQKQEAFVK  600

Query  601  QLIGNCMQQGMSLGNIEIRKCPECGKPMRKINHAKGTFWGCTGYPDCQHKEADkkvksts  660
            QLIG+CMQQGMSLGNIEIRKC+ECGKPMRKINHAKGTFWGCTGYPDCQHKEADKKVKS+S
Sbjct  601  QLIGSCMQQGMSLGNIEIRKCSECGKPMRKINHAKGTFWGCTGYPDCQHKEADKKVKSAS  660

Query  661  nkstkknsslnvlDQLNKLRSQL  683
            NKS+KK+S+LNVLDQLNKLRSQL
Sbjct  661  NKSAKKSSNLNVLDQLNKLRSQL  683

> NC_016808_R1|63|G56|378773985|YP_005176228.1|Pasteurella_multocida_36950|-|54272..56323|topB1|Pmu_03290|DNA 
topoisomerase 
III
Length=683

 Score = 1038 bits (3934),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 630/683 (93%), Positives = 670/683 (99%), Gaps = 0/683 (0%)

Query  1    MKLFICEKPSQARDLASVLGATSKGDGLLATNDKSIIVTWGFGHLVEQYQPEDYDEVWKR  60
            MKLFICEKPSQARDLA+VLGATSKG+GLLAT DKSIIVTWGFGHLVEQYQPEDYDE WKR
Sbjct  1    MKLFICEKPSQARDLAGVLGATSKGEGLLATADKSIIVTWGFGHLVEQYQPEDYDEAWKR  60

Query  61   WAFETLPIIPAQWKMAPKKESKKQYNVVIGLIKKASLVVIATDADREGEMIARELLDLAG  120
            WAFETLPIIPAQWKM+PKKESKKQY+VVIGLIKKA+ VVIATDADREGEMIARELLDLAG
Sbjct  61   WAFETLPIIPAQWKMTPKKESKKQYSVVIGLIKKATSVVIATDADREGEMIARELLDLAG  120

Query  121  YRGQIQRCWLSALDDASIRKALQTLKSGKETEALYYAGMGRSRSDWLIGMNFSRLFTLMA  180
            YRGQIQRCWLSALDDASIRKALQTLKSGKETEALYYAGMGRSRSDWLIGMNFSRLFTLMA
Sbjct  121  YRGQIQRCWLSALDDASIRKALQTLKSGKETEALYYAGMGRSRSDWLIGMNFSRLFTLMA  180

Query  181  QAKGYSGKPLSVGRVQSPTLALVVNRDREIANFVPKAHYSLAVQLATASDETFVAGLSIP  240
            QAKGYSGKPLSVGRVQSPTL+LVVNRDREIANFVPK+HY+LAVQL+T+S+ETFVAGL++P
Sbjct  181  QAKGYSGKPLSVGRVQSPTLTLVVNRDREIANFVPKSHYALAVQLTTTSGETFVAGLAVP  240

Query  241  EQYLDESGLCLDSRVIQQAEAQIKQVGIAKVITVETKREKKAPPLLYALSDLQGECNRLF  300
            EQYLDESGLCLDSRVIQQAEAQIKQ G+AKV+TVETKREKK+PPLLYALSDLQGECNRLF
Sbjct  241  EQYLDESGLCLDSRVIQQAEAQIKQTGLAKVVTVETKREKKSPPLLYALSDLQGECNRLF  300

Query  301  GFGAQQVLDIAQSLYEEHKITTYPRTDCGYLPESQLTEVPMVIRSLVAADSELQTLLPRL  360
            GFGAQQVLDIAQSLYEEHKITTYPRTDCGYLPESQ+++VP VIRSLVA+DS LQTLLP+L
Sbjct  301  GFGAQQVLDIAQSLYEEHKITTYPRTDCGYLPESQFSDVPNVIRSLVASDSGLQTLLPKL  360

Query  361  NLQQKSRAWDDKKITAHHGIIPTIKKADLSKLSEEEMKVYDLIRRRYLAQFLPHLETDKT  420
            NL+QKSRAWDDKKITAHHGIIPTIKKADLSKLSEEEMKVYDLIRRRYLAQFLPHLE DKT
Sbjct  361  NLRQKSRAWDDKKITAHHGIIPTIKKADLSKLSEEEMKVYDLIRRRYLAQFLPHLEMDKT  420

Query  421  IATLQSSGHTLIARGNVIVSQGWRILFGKNADEDVGSDDEKQGLPALTANQQCRVTHSEV  480
            +ATLQSSGHTL+ARGNVIV+QGWRILFGKN DE+ G+DDEKQGLP LT NQQC VTHSEV
Sbjct  421  VATLQSSGHTLVARGNVIVAQGWRILFGKNVDEETGNDDEKQGLPVLTKNQQCNVTHSEV  480

Query  481  RTLQTKPPAHYTEGTLLEAMKNAARFVTDPRLKQRLRETEGLGTEATRAGLIQGLIDKGF  540
            RTLQTKPPAHYTEGTLL+AMKNAARFVTDPRLKQRLRETEGLGTEATRAGLIQGLIDKGF
Sbjct  481  RTLQTKPPAHYTEGTLLDAMKNAARFVTDPRLKQRLRETEGLGTEATRAGLIQGLIDKGF  540

Query  541  LIKKKKSLMASAEAIALIDSLPDLLKNPGLTALWEQALNQIAEGSMTLDDFMQRQETFVR  600
            L+KKKKSL+ASAEA+ALIDSLPDLLKNPGLTALWEQALNQIAEGSMTLD FMQ+QE+FV+
Sbjct  541  LLKKKKSLVASAEAVALIDSLPDLLKNPGLTALWEQALNQIAEGSMTLDAFMQKQEAFVK  600

Query  601  QLIGNCMQQGMSLGNIEIRKCPECGKPMRKINHAKGTFWGCTGYPDCQHKEADkkvksts  660
            QLIG+CMQQGMSLGNIEIRKC+ECGKPMRKINHAKGTFWGCTGYPDCQHKEADKKVKS+S
Sbjct  601  QLIGSCMQQGMSLGNIEIRKCSECGKPMRKINHAKGTFWGCTGYPDCQHKEADKKVKSAS  660

Query  661  nkstkknsslnvlDQLNKLRSQL  683
            NKS+KK+S+LNVLDQLNKLRSQL
Sbjct  661  NKSAKKSSNLNVLDQLNKLRSQL  683

> NC_016808_R1|63|G56|378773985|YP_005176228.1|Pasteurella_multocida_36950|-|54272..56323|topB1|Pmu_03290|DNA 
topoisomerase 
III
Length=683

 Score = 1038 bits (3934),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 630/683 (93%), Positives = 670/683 (99%), Gaps = 0/683 (0%)

Query  1    MKLFICEKPSQARDLASVLGATSKGDGLLATNDKSIIVTWGFGHLVEQYQPEDYDEVWKR  60
            MKLFICEKPSQARDLA+VLGATSKG+GLLAT DKSIIVTWGFGHLVEQYQPEDYDE WKR
Sbjct  1    MKLFICEKPSQARDLAGVLGATSKGEGLLATADKSIIVTWGFGHLVEQYQPEDYDEAWKR  60

Query  61   WAFETLPIIPAQWKMAPKKESKKQYNVVIGLIKKASLVVIATDADREGEMIARELLDLAG  120
            WAFETLPIIPAQWKM+PKKESKKQY+VVIGLIKKA+ VVIATDADREGEMIARELLDLAG
Sbjct  61   WAFETLPIIPAQWKMTPKKESKKQYSVVIGLIKKATSVVIATDADREGEMIARELLDLAG  120

Query  121  YRGQIQRCWLSALDDASIRKALQTLKSGKETEALYYAGMGRSRSDWLIGMNFSRLFTLMA  180
            YRGQIQRCWLSALDDASIRKALQTLKSGKETEALYYAGMGRSRSDWLIGMNFSRLFTLMA
Sbjct  121  YRGQIQRCWLSALDDASIRKALQTLKSGKETEALYYAGMGRSRSDWLIGMNFSRLFTLMA  180

Query  181  QAKGYSGKPLSVGRVQSPTLALVVNRDREIANFVPKAHYSLAVQLATASDETFVAGLSIP  240
            QAKGYSGKPLSVGRVQSPTL+LVVNRDREIANFVPK+HY+LAVQL+T+S+ETFVAGL++P
Sbjct  181  QAKGYSGKPLSVGRVQSPTLTLVVNRDREIANFVPKSHYALAVQLTTTSGETFVAGLAVP  240

Query  241  EQYLDESGLCLDSRVIQQAEAQIKQVGIAKVITVETKREKKAPPLLYALSDLQGECNRLF  300
            EQYLDESGLCLDSRVIQQAEAQIKQ G+AKV+TVETKREKK+PPLLYALSDLQGECNRLF
Sbjct  241  EQYLDESGLCLDSRVIQQAEAQIKQTGLAKVVTVETKREKKSPPLLYALSDLQGECNRLF  300

Query  301  GFGAQQVLDIAQSLYEEHKITTYPRTDCGYLPESQLTEVPMVIRSLVAADSELQTLLPRL  360
            GFGAQQVLDIAQSLYEEHKITTYPRTDCGYLPESQ+++VP VIRSLVA+DS LQTLLP+L
Sbjct  301  GFGAQQVLDIAQSLYEEHKITTYPRTDCGYLPESQFSDVPNVIRSLVASDSGLQTLLPKL  360

Query  361  NLQQKSRAWDDKKITAHHGIIPTIKKADLSKLSEEEMKVYDLIRRRYLAQFLPHLETDKT  420
            NL+QKSRAWDDKKITAHHGIIPTIKKADLSKLSEEEMKVYDLIRRRYLAQFLPHLE DKT
Sbjct  361  NLRQKSRAWDDKKITAHHGIIPTIKKADLSKLSEEEMKVYDLIRRRYLAQFLPHLEMDKT  420

Query  421  IATLQSSGHTLIARGNVIVSQGWRILFGKNADEDVGSDDEKQGLPALTANQQCRVTHSEV  480
            +ATLQSSGHTL+ARGNVIV+QGWRILFGKN DE+ G+DDEKQGLP LT NQQC VTHSEV
Sbjct  421  VATLQSSGHTLVARGNVIVAQGWRILFGKNVDEETGNDDEKQGLPVLTKNQQCNVTHSEV  480

Query  481  RTLQTKPPAHYTEGTLLEAMKNAARFVTDPRLKQRLRETEGLGTEATRAGLIQGLIDKGF  540
            RTLQTKPPAHYTEGTLL+AMKNAARFVTDPRLKQRLRETEGLGTEATRAGLIQGLIDKGF
Sbjct  481  RTLQTKPPAHYTEGTLLDAMKNAARFVTDPRLKQRLRETEGLGTEATRAGLIQGLIDKGF  540

Query  541  LIKKKKSLMASAEAIALIDSLPDLLKNPGLTALWEQALNQIAEGSMTLDDFMQRQETFVR  600
            L+KKKKSL+ASAEA+ALIDSLPDLLKNPGLTALWEQALNQIAEGSMTLD FMQ+QE+FV+
Sbjct  541  LLKKKKSLVASAEAVALIDSLPDLLKNPGLTALWEQALNQIAEGSMTLDAFMQKQEAFVK  600

Query  601  QLIGNCMQQGMSLGNIEIRKCPECGKPMRKINHAKGTFWGCTGYPDCQHKEADkkvksts  660
            QLIG+CMQQGMSLGNIEIRKC+ECGKPMRKINHAKGTFWGCTGYPDCQHKEADKKVKS+S
Sbjct  601  QLIGSCMQQGMSLGNIEIRKCSECGKPMRKINHAKGTFWGCTGYPDCQHKEADKKVKSAS  660

Query  661  nkstkknsslnvlDQLNKLRSQL  683
            NKS+KK+S+LNVLDQLNKLRSQL
Sbjct  661  NKSAKKSSNLNVLDQLNKLRSQL  683

> NC_016808_R1|63|G56|378773985|YP_005176228.1|Pasteurella_multocida_36950|-|54272..56323|topB1|Pmu_03290|DNA 
topoisomerase 
III
Length=683

 Score = 1038 bits (3934),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 630/683 (93%), Positives = 670/683 (99%), Gaps = 0/683 (0%)

Query  1    MKLFICEKPSQARDLASVLGATSKGDGLLATNDKSIIVTWGFGHLVEQYQPEDYDEVWKR  60
            MKLFICEKPSQARDLA+VLGATSKG+GLLAT DKSIIVTWGFGHLVEQYQPEDYDE WKR
Sbjct  1    MKLFICEKPSQARDLAGVLGATSKGEGLLATADKSIIVTWGFGHLVEQYQPEDYDEAWKR  60

Query  61   WAFETLPIIPAQWKMAPKKESKKQYNVVIGLIKKASLVVIATDADREGEMIARELLDLAG  120
            WAFETLPIIPAQWKM+PKKESKKQY+VVIGLIKKA+ VVIATDADREGEMIARELLDLAG
Sbjct  61   WAFETLPIIPAQWKMTPKKESKKQYSVVIGLIKKATSVVIATDADREGEMIARELLDLAG  120

Query  121  YRGQIQRCWLSALDDASIRKALQTLKSGKETEALYYAGMGRSRSDWLIGMNFSRLFTLMA  180
            YRGQIQRCWLSALDDASIRKALQTLKSGKETEALYYAGMGRSRSDWLIGMNFSRLFTLMA
Sbjct  121  YRGQIQRCWLSALDDASIRKALQTLKSGKETEALYYAGMGRSRSDWLIGMNFSRLFTLMA  180

Query  181  QAKGYSGKPLSVGRVQSPTLALVVNRDREIANFVPKAHYSLAVQLATASDETFVAGLSIP  240
            QAKGYSGKPLSVGRVQSPTL+LVVNRDREIANFVPK+HY+LAVQL+T+S+ETFVAGL++P
Sbjct  181  QAKGYSGKPLSVGRVQSPTLTLVVNRDREIANFVPKSHYALAVQLTTTSGETFVAGLAVP  240

Query  241  EQYLDESGLCLDSRVIQQAEAQIKQVGIAKVITVETKREKKAPPLLYALSDLQGECNRLF  300
            EQYLDESGLCLDSRVIQQAEAQIKQ G+AKV+TVETKREKK+PPLLYALSDLQGECNRLF
Sbjct  241  EQYLDESGLCLDSRVIQQAEAQIKQTGLAKVVTVETKREKKSPPLLYALSDLQGECNRLF  300

Query  301  GFGAQQVLDIAQSLYEEHKITTYPRTDCGYLPESQLTEVPMVIRSLVAADSELQTLLPRL  360
            GFGAQQVLDIAQSLYEEHKITTYPRTDCGYLPESQ+++VP VIRSLVA+DS LQTLLP+L
Sbjct  301  GFGAQQVLDIAQSLYEEHKITTYPRTDCGYLPESQFSDVPNVIRSLVASDSGLQTLLPKL  360

Query  361  NLQQKSRAWDDKKITAHHGIIPTIKKADLSKLSEEEMKVYDLIRRRYLAQFLPHLETDKT  420
            NL+QKSRAWDDKKITAHHGIIPTIKKADLSKLSEEEMKVYDLIRRRYLAQFLPHLE DKT
Sbjct  361  NLRQKSRAWDDKKITAHHGIIPTIKKADLSKLSEEEMKVYDLIRRRYLAQFLPHLEMDKT  420

Query  421  IATLQSSGHTLIARGNVIVSQGWRILFGKNADEDVGSDDEKQGLPALTANQQCRVTHSEV  480
            +ATLQSSGHTL+ARGNVIV+QGWRILFGKN DE+ G+DDEKQGLP LT NQQC VTHSEV
Sbjct  421  VATLQSSGHTLVARGNVIVAQGWRILFGKNVDEETGNDDEKQGLPVLTKNQQCNVTHSEV  480

Query  481  RTLQTKPPAHYTEGTLLEAMKNAARFVTDPRLKQRLRETEGLGTEATRAGLIQGLIDKGF  540
            RTLQTKPPAHYTEGTLL+AMKNAARFVTDPRLKQRLRETEGLGTEATRAGLIQGLIDKGF
Sbjct  481  RTLQTKPPAHYTEGTLLDAMKNAARFVTDPRLKQRLRETEGLGTEATRAGLIQGLIDKGF  540

Query  541  LIKKKKSLMASAEAIALIDSLPDLLKNPGLTALWEQALNQIAEGSMTLDDFMQRQETFVR  600
            L+KKKKSL+ASAEA+ALIDSLPDLLKNPGLTALWEQALNQIAEGSMTLD FMQ+QE+FV+
Sbjct  541  LLKKKKSLVASAEAVALIDSLPDLLKNPGLTALWEQALNQIAEGSMTLDAFMQKQEAFVK  600

Query  601  QLIGNCMQQGMSLGNIEIRKCPECGKPMRKINHAKGTFWGCTGYPDCQHKEADkkvksts  660
            QLIG+CMQQGMSLGNIEIRKC+ECGKPMRKINHAKGTFWGCTGYPDCQHKEADKKVKS+S
Sbjct  601  QLIGSCMQQGMSLGNIEIRKCSECGKPMRKINHAKGTFWGCTGYPDCQHKEADKKVKSAS  660

Query  661  nkstkknsslnvlDQLNKLRSQL  683
            NKS+KK+S+LNVLDQLNKLRSQL
Sbjct  661  NKSAKKSSNLNVLDQLNKLRSQL  683

> NC_016808_R1|63|G56|378773985|YP_005176228.1|Pasteurella_multocida_36950|-|54272..56323|topB1|Pmu_03290|DNA 
topoisomerase 
III
Length=683

 Score = 1038 bits (3934),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 630/683 (93%), Positives = 670/683 (99%), Gaps = 0/683 (0%)

Query  1    MKLFICEKPSQARDLASVLGATSKGDGLLATNDKSIIVTWGFGHLVEQYQPEDYDEVWKR  60
            MKLFICEKPSQARDLA+VLGATSKG+GLLAT DKSIIVTWGFGHLVEQYQPEDYDE WKR
Sbjct  1    MKLFICEKPSQARDLAGVLGATSKGEGLLATADKSIIVTWGFGHLVEQYQPEDYDEAWKR  60

Query  61   WAFETLPIIPAQWKMAPKKESKKQYNVVIGLIKKASLVVIATDADREGEMIARELLDLAG  120
            WAFETLPIIPAQWKM+PKKESKKQY+VVIGLIKKA+ VVIATDADREGEMIARELLDLAG
Sbjct  61   WAFETLPIIPAQWKMTPKKESKKQYSVVIGLIKKATSVVIATDADREGEMIARELLDLAG  120

Query  121  YRGQIQRCWLSALDDASIRKALQTLKSGKETEALYYAGMGRSRSDWLIGMNFSRLFTLMA  180
            YRGQIQRCWLSALDDASIRKALQTLKSGKETEALYYAGMGRSRSDWLIGMNFSRLFTLMA
Sbjct  121  YRGQIQRCWLSALDDASIRKALQTLKSGKETEALYYAGMGRSRSDWLIGMNFSRLFTLMA  180

Query  181  QAKGYSGKPLSVGRVQSPTLALVVNRDREIANFVPKAHYSLAVQLATASDETFVAGLSIP  240
            QAKGYSGKPLSVGRVQSPTL+LVVNRDREIANFVPK+HY+LAVQL+T+S+ETFVAGL++P
Sbjct  181  QAKGYSGKPLSVGRVQSPTLTLVVNRDREIANFVPKSHYALAVQLTTTSGETFVAGLAVP  240

Query  241  EQYLDESGLCLDSRVIQQAEAQIKQVGIAKVITVETKREKKAPPLLYALSDLQGECNRLF  300
            EQYLDESGLCLDSRVIQQAEAQIKQ G+AKV+TVETKREKK+PPLLYALSDLQGECNRLF
Sbjct  241  EQYLDESGLCLDSRVIQQAEAQIKQTGLAKVVTVETKREKKSPPLLYALSDLQGECNRLF  300

Query  301  GFGAQQVLDIAQSLYEEHKITTYPRTDCGYLPESQLTEVPMVIRSLVAADSELQTLLPRL  360
            GFGAQQVLDIAQSLYEEHKITTYPRTDCGYLPESQ+++VP VIRSLVA+DS LQTLLP+L
Sbjct  301  GFGAQQVLDIAQSLYEEHKITTYPRTDCGYLPESQFSDVPNVIRSLVASDSGLQTLLPKL  360

Query  361  NLQQKSRAWDDKKITAHHGIIPTIKKADLSKLSEEEMKVYDLIRRRYLAQFLPHLETDKT  420
            NL+QKSRAWDDKKITAHHGIIPTIKKADLSKLSEEEMKVYDLIRRRYLAQFLPHLE DKT
Sbjct  361  NLRQKSRAWDDKKITAHHGIIPTIKKADLSKLSEEEMKVYDLIRRRYLAQFLPHLEMDKT  420

Query  421  IATLQSSGHTLIARGNVIVSQGWRILFGKNADEDVGSDDEKQGLPALTANQQCRVTHSEV  480
            +ATLQSSGHTL+ARGNVIV+QGWRILFGKN DE+ G+DDEKQGLP LT NQQC VTHSEV
Sbjct  421  VATLQSSGHTLVARGNVIVAQGWRILFGKNVDEETGNDDEKQGLPVLTKNQQCNVTHSEV  480

Query  481  RTLQTKPPAHYTEGTLLEAMKNAARFVTDPRLKQRLRETEGLGTEATRAGLIQGLIDKGF  540
            RTLQTKPPAHYTEGTLL+AMKNAARFVTDPRLKQRLRETEGLGTEATRAGLIQGLIDKGF
Sbjct  481  RTLQTKPPAHYTEGTLLDAMKNAARFVTDPRLKQRLRETEGLGTEATRAGLIQGLIDKGF  540

Query  541  LIKKKKSLMASAEAIALIDSLPDLLKNPGLTALWEQALNQIAEGSMTLDDFMQRQETFVR  600
            L+KKKKSL+ASAEA+ALIDSLPDLLKNPGLTALWEQALNQIAEGSMTLD FMQ+QE+FV+
Sbjct  541  LLKKKKSLVASAEAVALIDSLPDLLKNPGLTALWEQALNQIAEGSMTLDAFMQKQEAFVK  600

Query  601  QLIGNCMQQGMSLGNIEIRKCPECGKPMRKINHAKGTFWGCTGYPDCQHKEADkkvksts  660
            QLIG+CMQQGMSLGNIEIRKC+ECGKPMRKINHAKGTFWGCTGYPDCQHKEADKKVKS+S
Sbjct  601  QLIGSCMQQGMSLGNIEIRKCSECGKPMRKINHAKGTFWGCTGYPDCQHKEADKKVKSAS  660

Query  661  nkstkknsslnvlDQLNKLRSQL  683
            NKS+KK+S+LNVLDQLNKLRSQL
Sbjct  661  NKSAKKSSNLNVLDQLNKLRSQL  683

> NC_016808_R1|63|G56|378773985|YP_005176228.1|Pasteurella_multocida_36950|-|54272..56323|topB1|Pmu_03290|DNA 
topoisomerase 
III
Length=683

 Score = 1022 bits (3875),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 683/683 (100%), Positives = 683/683 (100%), Gaps = 0/683 (0%)

Query  1    MKLFICEKPSQARDLAGVLGATSKGEGLLATADKSIIVTWGFGHLVEQYQPEDYDEAWKR  60
            MKLFICEKPSQARDLAGVLGATSKGEGLLATADKSIIVTWGFGHLVEQYQPEDYDEAWKR
Sbjct  1    MKLFICEKPSQARDLAGVLGATSKGEGLLATADKSIIVTWGFGHLVEQYQPEDYDEAWKR  60

Query  61   WAFETLPIIPAQWKMTPKKESKKQYSVVIGLIKKATSVVIATDADREGEMIARELLDLAG  120
            WAFETLPIIPAQWKMTPKKESKKQYSVVIGLIKKATSVVIATDADREGEMIARELLDLAG
Sbjct  61   WAFETLPIIPAQWKMTPKKESKKQYSVVIGLIKKATSVVIATDADREGEMIARELLDLAG  120

Query  121  YRGQIQRCWLSALDDASIRKALQTLKSGKETEALYYAGMGRSRSDWLIGMNFSRLFTLMA  180
            YRGQIQRCWLSALDDASIRKALQTLKSGKETEALYYAGMGRSRSDWLIGMNFSRLFTLMA
Sbjct  121  YRGQIQRCWLSALDDASIRKALQTLKSGKETEALYYAGMGRSRSDWLIGMNFSRLFTLMA  180

Query  181  QAKGYSGKPLSVGRVQSPTLTLVVNRDREIANFVPKSHYALAVQLTTTSGETFVAGLAVP  240
            QAKGYSGKPLSVGRVQSPTLTLVVNRDREIANFVPKSHYALAVQLTTTSGETFVAGLAVP
Sbjct  181  QAKGYSGKPLSVGRVQSPTLTLVVNRDREIANFVPKSHYALAVQLTTTSGETFVAGLAVP  240

Query  241  EQYLDESGLCLDSRVIQQAEAQIKQTGLAkvvtvetkrekkSPPLLYALSDLQGECNRLF  300
            EQYLDESGLCLDSRVIQQAEAQIKQTGLAKVVTVETKREKKSPPLLYALSDLQGECNRLF
Sbjct  241  EQYLDESGLCLDSRVIQQAEAQIKQTGLAKVVTVETKREKKSPPLLYALSDLQGECNRLF  300

Query  301  GFGAQQVLDIAQSLYEEHKITTYPRTDCGYLPESQFSDVPNVIRSLVASDSGLQTLLPKL  360
            GFGAQQVLDIAQSLYEEHKITTYPRTDCGYLPESQFSDVPNVIRSLVASDSGLQTLLPKL
Sbjct  301  GFGAQQVLDIAQSLYEEHKITTYPRTDCGYLPESQFSDVPNVIRSLVASDSGLQTLLPKL  360

Query  361  NLRQKSRAWDDKKITAHHGIIPTIKKADLSKLSEEEMKVYDLIRRRYLAQFLPHLEMDKT  420
            NLRQKSRAWDDKKITAHHGIIPTIKKADLSKLSEEEMKVYDLIRRRYLAQFLPHLEMDKT
Sbjct  361  NLRQKSRAWDDKKITAHHGIIPTIKKADLSKLSEEEMKVYDLIRRRYLAQFLPHLEMDKT  420

Query  421  VATLQSSGHTLVARGNVIVAQGWRILFGKNVDEETGNDDEKQGLPVLTKNQQCNVTHSEV  480
            VATLQSSGHTLVARGNVIVAQGWRILFGKNVDEETGNDDEKQGLPVLTKNQQCNVTHSEV
Sbjct  421  VATLQSSGHTLVARGNVIVAQGWRILFGKNVDEETGNDDEKQGLPVLTKNQQCNVTHSEV  480

Query  481  RTLQTKPPAHYTEGTLLDAMKNAARFVTDPRLKQRLRETEGLGTEATRAGLIQGLIDKGF  540
            RTLQTKPPAHYTEGTLLDAMKNAARFVTDPRLKQRLRETEGLGTEATRAGLIQGLIDKGF
Sbjct  481  RTLQTKPPAHYTEGTLLDAMKNAARFVTDPRLKQRLRETEGLGTEATRAGLIQGLIDKGF  540

Query  541  llkkkkslvasaeavalIDSLPDLLKNPGLTALWEQALNQIAEGSMTLDAFMQKQEAFVK  600
            LLKKKKSLVASAEAVALIDSLPDLLKNPGLTALWEQALNQIAEGSMTLDAFMQKQEAFVK
Sbjct  541  LLKKKKSLVASAEAVALIDSLPDLLKNPGLTALWEQALNQIAEGSMTLDAFMQKQEAFVK  600

Query  601  QLIGSCMQQGMSLGNIEIRKCSECGKPMRKINHAKGTFWGCTGYPDCQHKEADkkvksas  660
            QLIGSCMQQGMSLGNIEIRKCSECGKPMRKINHAKGTFWGCTGYPDCQHKEADKKVKSAS
Sbjct  601  QLIGSCMQQGMSLGNIEIRKCSECGKPMRKINHAKGTFWGCTGYPDCQHKEADKKVKSAS  660

Query  661  nksakkssnlnvlDQLNKLRSQL  683
            NKSAKKSSNLNVLDQLNKLRSQL
Sbjct  661  NKSAKKSSNLNVLDQLNKLRSQL  683

> NC_016808_R1|63|G56|378773985|YP_005176228.1|Pasteurella_multocida_36950|-|54272..56323|topB1|Pmu_03290|DNA 
topoisomerase 
III
Length=683

 Score = 1022 bits (3875),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 683/683 (100%), Positives = 683/683 (100%), Gaps = 0/683 (0%)

Query  1    MKLFICEKPSQARDLAGVLGATSKGEGLLATADKSIIVTWGFGHLVEQYQPEDYDEAWKR  60
            MKLFICEKPSQARDLAGVLGATSKGEGLLATADKSIIVTWGFGHLVEQYQPEDYDEAWKR
Sbjct  1    MKLFICEKPSQARDLAGVLGATSKGEGLLATADKSIIVTWGFGHLVEQYQPEDYDEAWKR  60

Query  61   WAFETLPIIPAQWKMTPKKESKKQYSVVIGLIKKATSVVIATDADREGEMIARELLDLAG  120
            WAFETLPIIPAQWKMTPKKESKKQYSVVIGLIKKATSVVIATDADREGEMIARELLDLAG
Sbjct  61   WAFETLPIIPAQWKMTPKKESKKQYSVVIGLIKKATSVVIATDADREGEMIARELLDLAG  120

Query  121  YRGQIQRCWLSALDDASIRKALQTLKSGKETEALYYAGMGRSRSDWLIGMNFSRLFTLMA  180
            YRGQIQRCWLSALDDASIRKALQTLKSGKETEALYYAGMGRSRSDWLIGMNFSRLFTLMA
Sbjct  121  YRGQIQRCWLSALDDASIRKALQTLKSGKETEALYYAGMGRSRSDWLIGMNFSRLFTLMA  180

Query  181  QAKGYSGKPLSVGRVQSPTLTLVVNRDREIANFVPKSHYALAVQLTTTSGETFVAGLAVP  240
            QAKGYSGKPLSVGRVQSPTLTLVVNRDREIANFVPKSHYALAVQLTTTSGETFVAGLAVP
Sbjct  181  QAKGYSGKPLSVGRVQSPTLTLVVNRDREIANFVPKSHYALAVQLTTTSGETFVAGLAVP  240

Query  241  EQYLDESGLCLDSRVIQQAEAQIKQTGLAkvvtvetkrekkSPPLLYALSDLQGECNRLF  300
            EQYLDESGLCLDSRVIQQAEAQIKQTGLAKVVTVETKREKKSPPLLYALSDLQGECNRLF
Sbjct  241  EQYLDESGLCLDSRVIQQAEAQIKQTGLAKVVTVETKREKKSPPLLYALSDLQGECNRLF  300

Query  301  GFGAQQVLDIAQSLYEEHKITTYPRTDCGYLPESQFSDVPNVIRSLVASDSGLQTLLPKL  360
            GFGAQQVLDIAQSLYEEHKITTYPRTDCGYLPESQFSDVPNVIRSLVASDSGLQTLLPKL
Sbjct  301  GFGAQQVLDIAQSLYEEHKITTYPRTDCGYLPESQFSDVPNVIRSLVASDSGLQTLLPKL  360

Query  361  NLRQKSRAWDDKKITAHHGIIPTIKKADLSKLSEEEMKVYDLIRRRYLAQFLPHLEMDKT  420
            NLRQKSRAWDDKKITAHHGIIPTIKKADLSKLSEEEMKVYDLIRRRYLAQFLPHLEMDKT
Sbjct  361  NLRQKSRAWDDKKITAHHGIIPTIKKADLSKLSEEEMKVYDLIRRRYLAQFLPHLEMDKT  420

Query  421  VATLQSSGHTLVARGNVIVAQGWRILFGKNVDEETGNDDEKQGLPVLTKNQQCNVTHSEV  480
            VATLQSSGHTLVARGNVIVAQGWRILFGKNVDEETGNDDEKQGLPVLTKNQQCNVTHSEV
Sbjct  421  VATLQSSGHTLVARGNVIVAQGWRILFGKNVDEETGNDDEKQGLPVLTKNQQCNVTHSEV  480

Query  481  RTLQTKPPAHYTEGTLLDAMKNAARFVTDPRLKQRLRETEGLGTEATRAGLIQGLIDKGF  540
            RTLQTKPPAHYTEGTLLDAMKNAARFVTDPRLKQRLRETEGLGTEATRAGLIQGLIDKGF
Sbjct  481  RTLQTKPPAHYTEGTLLDAMKNAARFVTDPRLKQRLRETEGLGTEATRAGLIQGLIDKGF  540

Query  541  llkkkkslvasaeavalIDSLPDLLKNPGLTALWEQALNQIAEGSMTLDAFMQKQEAFVK  600
            LLKKKKSLVASAEAVALIDSLPDLLKNPGLTALWEQALNQIAEGSMTLDAFMQKQEAFVK
Sbjct  541  LLKKKKSLVASAEAVALIDSLPDLLKNPGLTALWEQALNQIAEGSMTLDAFMQKQEAFVK  600

Query  601  QLIGSCMQQGMSLGNIEIRKCSECGKPMRKINHAKGTFWGCTGYPDCQHKEADkkvksas  660
            QLIGSCMQQGMSLGNIEIRKCSECGKPMRKINHAKGTFWGCTGYPDCQHKEADKKVKSAS
Sbjct  601  QLIGSCMQQGMSLGNIEIRKCSECGKPMRKINHAKGTFWGCTGYPDCQHKEADKKVKSAS  660

Query  661  nksakkssnlnvlDQLNKLRSQL  683
            NKSAKKSSNLNVLDQLNKLRSQL
Sbjct  661  NKSAKKSSNLNVLDQLNKLRSQL  683

> NC_016808_R1|63|G56|378773985|YP_005176228.1|Pasteurella_multocida_36950|-|54272..56323|topB1|Pmu_03290|DNA 
topoisomerase 
III
Length=683

 Score = 1022 bits (3875),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 683/683 (100%), Positives = 683/683 (100%), Gaps = 0/683 (0%)

Query  1    MKLFICEKPSQARDLAGVLGATSKGEGLLATADKSIIVTWGFGHLVEQYQPEDYDEAWKR  60
            MKLFICEKPSQARDLAGVLGATSKGEGLLATADKSIIVTWGFGHLVEQYQPEDYDEAWKR
Sbjct  1    MKLFICEKPSQARDLAGVLGATSKGEGLLATADKSIIVTWGFGHLVEQYQPEDYDEAWKR  60

Query  61   WAFETLPIIPAQWKMTPKKESKKQYSVVIGLIKKATSVVIATDADREGEMIARELLDLAG  120
            WAFETLPIIPAQWKMTPKKESKKQYSVVIGLIKKATSVVIATDADREGEMIARELLDLAG
Sbjct  61   WAFETLPIIPAQWKMTPKKESKKQYSVVIGLIKKATSVVIATDADREGEMIARELLDLAG  120

Query  121  YRGQIQRCWLSALDDASIRKALQTLKSGKETEALYYAGMGRSRSDWLIGMNFSRLFTLMA  180
            YRGQIQRCWLSALDDASIRKALQTLKSGKETEALYYAGMGRSRSDWLIGMNFSRLFTLMA
Sbjct  121  YRGQIQRCWLSALDDASIRKALQTLKSGKETEALYYAGMGRSRSDWLIGMNFSRLFTLMA  180

Query  181  QAKGYSGKPLSVGRVQSPTLTLVVNRDREIANFVPKSHYALAVQLTTTSGETFVAGLAVP  240
            QAKGYSGKPLSVGRVQSPTLTLVVNRDREIANFVPKSHYALAVQLTTTSGETFVAGLAVP
Sbjct  181  QAKGYSGKPLSVGRVQSPTLTLVVNRDREIANFVPKSHYALAVQLTTTSGETFVAGLAVP  240

Query  241  EQYLDESGLCLDSRVIQQAEAQIKQTGLAkvvtvetkrekkSPPLLYALSDLQGECNRLF  300
            EQYLDESGLCLDSRVIQQAEAQIKQTGLAKVVTVETKREKKSPPLLYALSDLQGECNRLF
Sbjct  241  EQYLDESGLCLDSRVIQQAEAQIKQTGLAKVVTVETKREKKSPPLLYALSDLQGECNRLF  300

Query  301  GFGAQQVLDIAQSLYEEHKITTYPRTDCGYLPESQFSDVPNVIRSLVASDSGLQTLLPKL  360
            GFGAQQVLDIAQSLYEEHKITTYPRTDCGYLPESQFSDVPNVIRSLVASDSGLQTLLPKL
Sbjct  301  GFGAQQVLDIAQSLYEEHKITTYPRTDCGYLPESQFSDVPNVIRSLVASDSGLQTLLPKL  360

Query  361  NLRQKSRAWDDKKITAHHGIIPTIKKADLSKLSEEEMKVYDLIRRRYLAQFLPHLEMDKT  420
            NLRQKSRAWDDKKITAHHGIIPTIKKADLSKLSEEEMKVYDLIRRRYLAQFLPHLEMDKT
Sbjct  361  NLRQKSRAWDDKKITAHHGIIPTIKKADLSKLSEEEMKVYDLIRRRYLAQFLPHLEMDKT  420

Query  421  VATLQSSGHTLVARGNVIVAQGWRILFGKNVDEETGNDDEKQGLPVLTKNQQCNVTHSEV  480
            VATLQSSGHTLVARGNVIVAQGWRILFGKNVDEETGNDDEKQGLPVLTKNQQCNVTHSEV
Sbjct  421  VATLQSSGHTLVARGNVIVAQGWRILFGKNVDEETGNDDEKQGLPVLTKNQQCNVTHSEV  480

Query  481  RTLQTKPPAHYTEGTLLDAMKNAARFVTDPRLKQRLRETEGLGTEATRAGLIQGLIDKGF  540
            RTLQTKPPAHYTEGTLLDAMKNAARFVTDPRLKQRLRETEGLGTEATRAGLIQGLIDKGF
Sbjct  481  RTLQTKPPAHYTEGTLLDAMKNAARFVTDPRLKQRLRETEGLGTEATRAGLIQGLIDKGF  540

Query  541  llkkkkslvasaeavalIDSLPDLLKNPGLTALWEQALNQIAEGSMTLDAFMQKQEAFVK  600
            LLKKKKSLVASAEAVALIDSLPDLLKNPGLTALWEQALNQIAEGSMTLDAFMQKQEAFVK
Sbjct  541  LLKKKKSLVASAEAVALIDSLPDLLKNPGLTALWEQALNQIAEGSMTLDAFMQKQEAFVK  600

Query  601  QLIGSCMQQGMSLGNIEIRKCSECGKPMRKINHAKGTFWGCTGYPDCQHKEADkkvksas  660
            QLIGSCMQQGMSLGNIEIRKCSECGKPMRKINHAKGTFWGCTGYPDCQHKEADKKVKSAS
Sbjct  601  QLIGSCMQQGMSLGNIEIRKCSECGKPMRKINHAKGTFWGCTGYPDCQHKEADKKVKSAS  660

Query  661  nksakkssnlnvlDQLNKLRSQL  683
            NKSAKKSSNLNVLDQLNKLRSQL
Sbjct  661  NKSAKKSSNLNVLDQLNKLRSQL  683

> NC_016808_R1|63|G56|378773985|YP_005176228.1|Pasteurella_multocida_36950|-|54272..56323|topB1|Pmu_03290|DNA 
topoisomerase 
III
Length=683

 Score =  749 bits (2834),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 440/652 (68%), Positives = 553/652 (85%), Gaps = 4/652 (0%)

Query  6    MKLFLCEKPSQGNDIAKVLGATKRGEGCLSTPDGQLTVTWGIGHLVEQFNPEEYDPAFKK  65
            MKLF+CEKPSQ+ D+A VLGAT +GEG L+T+D  + VTWG+GHLVEQ++PE+YD A K+
Sbjct  1    MKLFICEKPSQARDLAGVLGATSKGEGLLATADKSIIVTWGFGHLVEQYQPEDYDEAWKR  60

Query  66   WAFETLPIIPGKWGLSPKKETKKQFNVVMKLIKQAKLVVIATDIDREGETIARELLDLAG  125
            WAFETLPIIP++W ++PKKE+KKQ++VV+ LIK+A  VVIATD DREGE IARELLDLAG
Sbjct  61   WAFETLPIIPAQWKMTPKKESKKQYSVVIGLIKKATSVVIATDADREGEMIARELLDLAG  120

Query  126  FRGQIKRLWLSALDDTSIRKALGALKNNEETLPLYYAGLARSRADWLIGMNFSRLYTLLA  185
            +RGQI+R WLSALDD+SIRKAL +LK+  ET +LYYAG++RSR+DWLIGMNFSRL+TL+A
Sbjct  121  YRGQIQRCWLSALDDASIRKALQTLKSGKETEALYYAGMGRSRSDWLIGMNFSRLFTLMA  180

Query  186  QQQGYQGKPLSVGRVQTPTLSLVVNRDREIKNFIPKQHFALQVML-SDGNQHFATQYVIP  244
            Q +GY GKPLSVGRVQ+PTL+LVVNRDREI NF+PK H+AL V L + + + F +   +P
Sbjct  181  QAKGYSGKPLSVGRVQSPTLTLVVNRDREIANFVPKSHYALAVQLTTTSGETFVAGLAVP  240

Query  245  EQYCDPDGLCLSAQVIQAANQQIRQFGQAKVESVETKRERQNAPLCFALSDLQSEANRLY  304
            EQY D  GLCL ++VIQ A+ QI+Q G AKV +VETKRE++++PL +ALSDLQ+E NRL+
Sbjct  241  EQYLDESGLCLDSRVIQQAEAQIKQTGLAKVVTVETKREKKSPPLLYALSDLQGECNRLF  300

Query  305  GLGAQRVLDIAQSLYETHKATTYPRTDCGYLPESQFAEAPQIIQCLLQSDNRLHPLAGML  364
            G+GAQ+VLDIAQSLYE HK TTYPRTDCGYLPESQF++ P++I+ L+ SD+ L+ L   L
Sbjct  301  GFGAQQVLDIAQSLYEEHKITTYPRTDCGYLPESQFSDVPNVIRSLVASDSGLQTLLPKL  360

Query  365  NLNQKSRVWNDKKITAHHGIIPTMIKADISKMSDEELKLYDLIRRRYLAQFLPVSETDKT  424
            NL QKSR W+DKKITAHHGIIPT+ KAD+SK+S+EE+K+YDLIRRRYLAQFLP  E DKT
Sbjct  361  NLRQKSRAWDDKKITAHHGIIPTIKKADLSKLSEEEMKVYDLIRRRYLAQFLPHLEMDKT  420

Query  425  QIILKCGQHILSARGNVLIAPGWKILFGKSLDED---DDAPQALPTLKQGQICQISDSEI  481
               L+ + H L ARGNV++A GW+ILFGK++DE+   DD  Q+LP L + Q C++++SE+
Sbjct  421  VATLQSSGHTLVARGNVIVAQGWRILFGKNVDEETGNDDEKQGLPVLTKNQQCNVTHSEV  480

Query  482  KTLQTSPPNHFTEGTLLTAMKNAARFVTDERLKQRLRETEGLGTEATRAGTIQglidkgf  541
            +TLQT PP H+TEGTLL AMKNAARFVTD RLKQRLRETEGLGTEATRAG IQGLIDKGF
Sbjct  481  RTLQTKPPAHYTEGTLLDAMKNAARFVTDPRLKQRLRETEGLGTEATRAGLIQGLIDKGF  540

Query  542  lkkkgksllATDEAMTLIDNLPQMLKDPGLTALWEQALNQIAERTLSLEVFMQKQEVFVR  601
            L KK KSL+A+ EA++LID+LP++LK+PGLTALWEQALNQIAE +++L+ FMQKQE FV+
Sbjct  541  LLKKKKSLVASAEAVALIDSLPDLLKNPGLTALWEQALNQIAEGSMTLDAFMQKQEAFVK  600

Query  602  HLMADCLKKGMSLGNIEIRKCPKCGAPMIKRNGKNGAFFGCSAYPNCQHIEN  653
            +L++ C+++GMSLGNIEIRKC+ CG PM K N  +G+F GC++YP+CQH E 
Sbjct  601  QLIGSCMQQGMSLGNIEIRKCSECGKPMRKINHAKGTFWGCTGYPDCQHKEA  652

> NC_016808_R1|63|G56|378773985|YP_005176228.1|Pasteurella_multocida_36950|-|54272..56323|topB1|Pmu_03290|DNA 
topoisomerase 
III
Length=683

 Score =  748 bits (2831),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 440/652 (68%), Positives = 553/652 (85%), Gaps = 4/652 (0%)

Query  1    MKLFLCEKPSQGNDIAKVLGATKRGEGCLSTPDGQLTVTWGIGHLVEQFNPEEYDPAFKK  60
            MKLF+CEKPSQ+ D+A VLGAT +GEG L+T+D  + VTWG+GHLVEQ++PE+YD A K+
Sbjct  1    MKLFICEKPSQARDLAGVLGATSKGEGLLATADKSIIVTWGFGHLVEQYQPEDYDEAWKR  60

Query  61   WAFETLPIIPGKWGLSPKKETKKQFNVVMKLIKQAKLVVIATDIDREGETIARELLDLAG  120
            WAFETLPIIP++W ++PKKE+KKQ++VV+ LIK+A  VVIATD DREGE IARELLDLAG
Sbjct  61   WAFETLPIIPAQWKMTPKKESKKQYSVVIGLIKKATSVVIATDADREGEMIARELLDLAG  120

Query  121  FRGQIKRLWLSALDDTSIRKALGALKNNEETLPLYYAGLARSRADWLIGMNFSRLYTLLA  180
            +RGQI+R WLSALDD+SIRKAL +LK+  ET +LYYAG++RSR+DWLIGMNFSRL+TL+A
Sbjct  121  YRGQIQRCWLSALDDASIRKALQTLKSGKETEALYYAGMGRSRSDWLIGMNFSRLFTLMA  180

Query  181  QQQGYQGKPLSVGRVQTPTLSLVVNRDREIKNFIPKQHFALQVML-SDGNQHFATQYVIP  239
            Q +GY GKPLSVGRVQ+PTL+LVVNRDREI NF+PK H+AL V L + + + F +   +P
Sbjct  181  QAKGYSGKPLSVGRVQSPTLTLVVNRDREIANFVPKSHYALAVQLTTTSGETFVAGLAVP  240

Query  240  EQYCDPDGLCLSAQVIQAANQQIRQFGQAKVESVETKRERQNAPLCFALSDLQSEANRLY  299
            EQY D  GLCL ++VIQ A+ QI+Q G AKV +VETKRE++++PL +ALSDLQ+E NRL+
Sbjct  241  EQYLDESGLCLDSRVIQQAEAQIKQTGLAKVVTVETKREKKSPPLLYALSDLQGECNRLF  300

Query  300  GLGAQRVLDIAQSLYETHKATTYPRTDCGYLPESQFAEAPQIIQCLLQSDNRLHPLAGML  359
            G+GAQ+VLDIAQSLYE HK TTYPRTDCGYLPESQF++ P++I+ L+ SD+ L+ L   L
Sbjct  301  GFGAQQVLDIAQSLYEEHKITTYPRTDCGYLPESQFSDVPNVIRSLVASDSGLQTLLPKL  360

Query  360  NLNQKSRVWNDKKITAHHGIIPTMIKADISKMSDEELKLYDLIRRRYLAQFLPVSETDKT  419
            NL QKSR W+DKKITAHHGIIPT+ KAD+SK+S+EE+K+YDLIRRRYLAQFLP  E DKT
Sbjct  361  NLRQKSRAWDDKKITAHHGIIPTIKKADLSKLSEEEMKVYDLIRRRYLAQFLPHLEMDKT  420

Query  420  QIILKCGQHILSARGNVLIAPGWKILFGKSLDED---DDAPQALPTLKQGQICQISDSEI  476
               L+ + H L ARGNV++A GW+ILFGK++DE+   DD  Q+LP L + Q C++++SE+
Sbjct  421  VATLQSSGHTLVARGNVIVAQGWRILFGKNVDEETGNDDEKQGLPVLTKNQQCNVTHSEV  480

Query  477  KTLQTSPPNHFTEGTLLTAMKNAARFVTDERLKQRLRETEGLGTEATRAGTIQglidkgf  536
            +TLQT PP H+TEGTLL AMKNAARFVTD RLKQRLRETEGLGTEATRAG IQGLIDKGF
Sbjct  481  RTLQTKPPAHYTEGTLLDAMKNAARFVTDPRLKQRLRETEGLGTEATRAGLIQGLIDKGF  540

Query  537  lkkkgksllATDEAMTLIDNLPQMLKDPGLTALWEQALNQIAERTLSLEVFMQKQEVFVR  596
            L KK KSL+A+ EA++LID+LP++LK+PGLTALWEQALNQIAE +++L+ FMQKQE FV+
Sbjct  541  LLKKKKSLVASAEAVALIDSLPDLLKNPGLTALWEQALNQIAEGSMTLDAFMQKQEAFVK  600

Query  597  HLMADCLKKGMSLGNIEIRKCPKCGAPMIKRNGKNGAFFGCSAYPNCQHIEN  648
            +L++ C+++GMSLGNIEIRKC+ CG PM K N  +G+F GC++YP+CQH E 
Sbjct  601  QLIGSCMQQGMSLGNIEIRKCSECGKPMRKINHAKGTFWGCTGYPDCQHKEA  652

> NC_016808_R1|63|G56|378773985|YP_005176228.1|Pasteurella_multocida_36950|-|54272..56323|topB1|Pmu_03290|DNA 
topoisomerase 
III
Length=683

 Score =  748 bits (2831),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 440/652 (68%), Positives = 553/652 (85%), Gaps = 4/652 (0%)

Query  1    MKLFLCEKPSQGNDIAKVLGATKRGEGCLSTPDGQLTVTWGIGHLVEQFNPEEYDPAFKK  60
            MKLF+CEKPSQ+ D+A VLGAT +GEG L+T+D  + VTWG+GHLVEQ++PE+YD A K+
Sbjct  1    MKLFICEKPSQARDLAGVLGATSKGEGLLATADKSIIVTWGFGHLVEQYQPEDYDEAWKR  60

Query  61   WAFETLPIIPGKWGLSPKKETKKQFNVVMKLIKQAKLVVIATDIDREGETIARELLDLAG  120
            WAFETLPIIP++W ++PKKE+KKQ++VV+ LIK+A  VVIATD DREGE IARELLDLAG
Sbjct  61   WAFETLPIIPAQWKMTPKKESKKQYSVVIGLIKKATSVVIATDADREGEMIARELLDLAG  120

Query  121  FRGQIKRLWLSALDDTSIRKALGALKNNEETLPLYYAGLARSRADWLIGMNFSRLYTLLA  180
            +RGQI+R WLSALDD+SIRKAL +LK+  ET +LYYAG++RSR+DWLIGMNFSRL+TL+A
Sbjct  121  YRGQIQRCWLSALDDASIRKALQTLKSGKETEALYYAGMGRSRSDWLIGMNFSRLFTLMA  180

Query  181  QQQGYQGKPLSVGRVQTPTLSLVVNRDREIKNFIPKQHFALQVML-SDGNQHFATQYVIP  239
            Q +GY GKPLSVGRVQ+PTL+LVVNRDREI NF+PK H+AL V L + + + F +   +P
Sbjct  181  QAKGYSGKPLSVGRVQSPTLTLVVNRDREIANFVPKSHYALAVQLTTTSGETFVAGLAVP  240

Query  240  EQYCDPDGLCLSAQVIQAANQQIRQFGQAKVESVETKRERQNAPLCFALSDLQSEANRLY  299
            EQY D  GLCL ++VIQ A+ QI+Q G AKV +VETKRE++++PL +ALSDLQ+E NRL+
Sbjct  241  EQYLDESGLCLDSRVIQQAEAQIKQTGLAKVVTVETKREKKSPPLLYALSDLQGECNRLF  300

Query  300  GLGAQRVLDIAQSLYETHKATTYPRTDCGYLPESQFAEAPQIIQCLLQSDNRLHPLAGML  359
            G+GAQ+VLDIAQSLYE HK TTYPRTDCGYLPESQF++ P++I+ L+ SD+ L+ L   L
Sbjct  301  GFGAQQVLDIAQSLYEEHKITTYPRTDCGYLPESQFSDVPNVIRSLVASDSGLQTLLPKL  360

Query  360  NLNQKSRVWNDKKITAHHGIIPTMIKADISKMSDEELKLYDLIRRRYLAQFLPVSETDKT  419
            NL QKSR W+DKKITAHHGIIPT+ KAD+SK+S+EE+K+YDLIRRRYLAQFLP  E DKT
Sbjct  361  NLRQKSRAWDDKKITAHHGIIPTIKKADLSKLSEEEMKVYDLIRRRYLAQFLPHLEMDKT  420

Query  420  QIILKCGQHILSARGNVLIAPGWKILFGKSLDED---DDAPQALPTLKQGQICQISDSEI  476
               L+ + H L ARGNV++A GW+ILFGK++DE+   DD  Q+LP L + Q C++++SE+
Sbjct  421  VATLQSSGHTLVARGNVIVAQGWRILFGKNVDEETGNDDEKQGLPVLTKNQQCNVTHSEV  480

Query  477  KTLQTSPPNHFTEGTLLTAMKNAARFVTDERLKQRLRETEGLGTEATRAGTIQglidkgf  536
            +TLQT PP H+TEGTLL AMKNAARFVTD RLKQRLRETEGLGTEATRAG IQGLIDKGF
Sbjct  481  RTLQTKPPAHYTEGTLLDAMKNAARFVTDPRLKQRLRETEGLGTEATRAGLIQGLIDKGF  540

Query  537  lkkkgksllATDEAMTLIDNLPQMLKDPGLTALWEQALNQIAERTLSLEVFMQKQEVFVR  596
            L KK KSL+A+ EA++LID+LP++LK+PGLTALWEQALNQIAE +++L+ FMQKQE FV+
Sbjct  541  LLKKKKSLVASAEAVALIDSLPDLLKNPGLTALWEQALNQIAEGSMTLDAFMQKQEAFVK  600

Query  597  HLMADCLKKGMSLGNIEIRKCPKCGAPMIKRNGKNGAFFGCSAYPNCQHIEN  648
            +L++ C+++GMSLGNIEIRKC+ CG PM K N  +G+F GC++YP+CQH E 
Sbjct  601  QLIGSCMQQGMSLGNIEIRKCSECGKPMRKINHAKGTFWGCTGYPDCQHKEA  652

> NC_016808_R1|63|G56|378773985|YP_005176228.1|Pasteurella_multocida_36950|-|54272..56323|topB1|Pmu_03290|DNA 
topoisomerase 
III
Length=683

 Score =  747 bits (2826),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 439/652 (68%), Positives = 552/652 (85%), Gaps = 4/652 (0%)

Query  1    MKLFLCEKPSQGNDIAKILGATKRGEGCLSTPDGQLTVTWGIGHLVEQFNPEEYDPAFKK  60
            MKLF+CEKPSQ+ D+A +LGAT +GEG L+T+D  + VTWG+GHLVEQ++PE+YD A K+
Sbjct  1    MKLFICEKPSQARDLAGVLGATSKGEGLLATADKSIIVTWGFGHLVEQYQPEDYDEAWKR  60

Query  61   WAFETLPIIPGKWGLSPKKETKKQFNVVMKLIKQAKLVVIATDIDREGETIARELLDLAG  120
            WAFETLPIIP++W ++PKKE+KKQ++VV+ LIK+A  VVIATD DREGE IARELLDLAG
Sbjct  61   WAFETLPIIPAQWKMTPKKESKKQYSVVIGLIKKATSVVIATDADREGEMIARELLDLAG  120

Query  121  FRGQIKRLWLSALDDASIRKALGALKDNEETLPLYYAGLARSRADWLIGMNFSRIYTLLA  180
            +RGQI+R WLSALDDASIRKAL +LK   ET +LYYAG++RSR+DWLIGMNFSR++TL+A
Sbjct  121  YRGQIQRCWLSALDDASIRKALQTLKSGKETEALYYAGMGRSRSDWLIGMNFSRLFTLMA  180

Query  181  QQQGYQGKPLSVGRVQTPTLSLVVNRDREIKNFIPKQHFALQVML-SDGNQHFATQYVIP  239
            Q +GY GKPLSVGRVQ+PTL+LVVNRDREI NF+PK H+AL V L + + + F +   +P
Sbjct  181  QAKGYSGKPLSVGRVQSPTLTLVVNRDREIANFVPKSHYALAVQLTTTSGETFVAGLAVP  240

Query  240  EQYCDPDGLCLSAQVIQAANQQIRQLGQAKMESVETKRERQNAPLCFALSDLQSEANRLY  299
            EQY D  GLCL ++VIQ A+ QI+Q G AK+ +VETKRE++++PL +ALSDLQ+E NRL+
Sbjct  241  EQYLDESGLCLDSRVIQQAEAQIKQTGLAKVVTVETKREKKSPPLLYALSDLQGECNRLF  300

Query  300  GLGAQRVLDIAQSLYETHKATTYPRTDCGYLPESQFAEAPKIIQCLLQSDNRLQPLAGML  359
            G+GAQ+VLDIAQSLYE HK TTYPRTDCGYLPESQF++ P++I+ L+ SD+ LQ L   L
Sbjct  301  GFGAQQVLDIAQSLYEEHKITTYPRTDCGYLPESQFSDVPNVIRSLVASDSGLQTLLPKL  360

Query  360  NLNQKSRVWNDKKITAHHGIIPTMIKADISKMSDEELKLYDLIRRRYLAQFLPVSETDKT  419
            NL QKSR W+DKKITAHHGIIPT+ KAD+SK+S+EE+K+YDLIRRRYLAQFLP  E DKT
Sbjct  361  NLRQKSRAWDDKKITAHHGIIPTIKKADLSKLSEEEMKVYDLIRRRYLAQFLPHLEMDKT  420

Query  420  QIILKCGQHILSARGNVLIAPGWKILFGKSLDED---DDAPQALPTLKQGQICQISDSEI  476
               L+ + H L ARGNV++A GW+ILFGK++DE+   DD  Q+LP L + Q C++++SE+
Sbjct  421  VATLQSSGHTLVARGNVIVAQGWRILFGKNVDEETGNDDEKQGLPVLTKNQQCNVTHSEV  480

Query  477  KTLQTSPPNHFTEGTLLTAMKNAARFVTDERLKQRLRETEGLGTEATRAGTIQglidkgf  536
            +TLQT PP H+TEGTLL AMKNAARFVTD RLKQRLRETEGLGTEATRAG IQGLIDKGF
Sbjct  481  RTLQTKPPAHYTEGTLLDAMKNAARFVTDPRLKQRLRETEGLGTEATRAGLIQGLIDKGF  540

Query  537  lkkkgksllATDEAMTLIDNLPQMLKDPGLTALWEQALNQIAERTLSLEVFMQKQEVFVR  596
            L KK KSL+A+ EA++LID+LP++LK+PGLTALWEQALNQIAE +++L+ FMQKQE FV+
Sbjct  541  LLKKKKSLVASAEAVALIDSLPDLLKNPGLTALWEQALNQIAEGSMTLDAFMQKQEAFVK  600

Query  597  HLMADCLKKGMSLGNIEIRKCPKCGAPMIKRNGKNGAFLGCSAYPNCQHIEN  648
            +L++ C+++GMSLGNIEIRKC+ CG PM K N  +G+F GC++YP+CQH E 
Sbjct  601  QLIGSCMQQGMSLGNIEIRKCSECGKPMRKINHAKGTFWGCTGYPDCQHKEA  652

> NC_016808_R1|63|G56|378773985|YP_005176228.1|Pasteurella_multocida_36950|-|54272..56323|topB1|Pmu_03290|DNA 
topoisomerase 
III
Length=683

 Score =  738 bits (2792),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 427/680 (63%), Positives = 559/680 (83%), Gaps = 8/680 (1%)

Query  1    MKLFLCEKPSQGRDIAKVLGATQKGEGYLSTADGTIVVTWARGHLVEHFSPEQYDPALKA  60
            MKLF+CEKPSQ+RD+A VLGAT KGEG L+TAD +I+VTW+ GHLVE++ PE+YD A K 
Sbjct  1    MKLFICEKPSQARDLAGVLGATSKGEGLLATADKSIIVTWGFGHLVEQYQPEDYDEAWKR  60

Query  61   WRLDTLPIIPSQWQVSPKPDAKKEYKTVMTLLKKARTVVISTDIDREGETIARELLDLAG  120
            W ++TLPIIP+QW+++PK ++KK+Y  V+ L+KKA +VVI+TD DREGE IARELLDLAG
Sbjct  61   WAFETLPIIPAQWKMTPKKESKKQYSVVIGLIKKATSVVIATDADREGEMIARELLDLAG  120

Query  121  YRGHIQRLWITALDEISVRKALSRLKTNEETLPLYYAGLARSRADWLIGMNFSRMFTLLA  180
            YRG+IQR W++ALD+ S+RKAL  LK+  ET +LYYAG++RSR+DWLIGMNFSR+FTL+A
Sbjct  121  YRGQIQRCWLSALDDASIRKALQTLKSGKETEALYYAGMGRSRSDWLIGMNFSRLFTLMA  180

Query  181  QQQGYQGPPLSVGRVQSPTLALVVNRDKEIAHFVPTYHYALMVQVCGTNAQSFEASLLVP  240
            Q +GY G PLSVGRVQSPTL+LVVNRD+EIA+FVP  HYAL VQ+  T++++F A+L VP
Sbjct  181  QAKGYSGKPLSVGRVQSPTLTLVVNRDREIANFVPKSHYALAVQLTTTSGETFVAGLAVP  240

Query  241  EQYCDEEGRCLEIKVLqqaeqqirqagqVCVQNVETKREKESPPLLFALSDLQAECNRLY  300
            EQY DE G CL+ +V+QQAE QI+Q+G   V  VETKREK SPPLL+ALSDLQ+ECNRL+
Sbjct  241  EQYLDESGLCLDSRVIQQAEAQIKQTGLAKVVTVETKREKKSPPLLYALSDLQGECNRLF  300

Query  301  DLGTQQVLDIAQSLYEKHKATTYPRTDCGYLPEAQLLEVPQVINSLMQSDAKLQPLRVQL  360
            ++G+QQVLDIAQSLYE HK TTYPRTDCGYLPE+Q+ +VP+VI SL+ SD+ LQ L  +L
Sbjct  301  GFGAQQVLDIAQSLYEEHKITTYPRTDCGYLPESQFSDVPNVIRSLVASDSGLQTLLPKL  360

Query  361  NLSQKSRAWNDKKITAHHGIIPTTQPVDIAKMNENEFKVYDLIRRRYLAQFLPHFEVDKT  420
            NL QKSRAW+DKKITAHHGIIPT +  D++K++E+E KVYDLIRRRYLAQFLPH+E+DKT
Sbjct  361  NLRQKSRAWDDKKITAHHGIIPTIKKADLSKLSEEEMKVYDLIRRRYLAQFLPHLEMDKT  420

Query  421  RVRLSCGEHQCIAKGQVIVSAGWKALFRASKEEQ----GEKQGLPILNSGQMLKVMNTEI  476
               L  + H  +A+G+VIV+ GW+ LF  + +E+    +EKQGLP+L   Q  +V ++E+
Sbjct  421  VATLQSSGHTLVARGNVIVAQGWRILFGKNVDEETGNDDEKQGLPVLTKNQQCNVTHSEV  480

Query  477  KSLKTTPPAHYTEGTLLTAMVNVARFVTDERLKKQLRETEGLGTEATRASIMKTLYDRGY  536
            ++L+T PPAHYTEGTLL AM N ARFVTD RLK++LRETEGLGTEATRA++++ L D+G+
Sbjct  481  RTLQTKPPAHYTEGTLLDAMKNAARFVTDPRLKQRLRETEGLGTEATRAGLIQGLIDKGF  540

Query  537  IKKKGKSIVATDAGVMLIDNLPTVLKDPGLTALWEQALNQIAENQMSLQEFMQKQEQFVL  596
            + KK KS+VA+  +V LID+LP +LK+PGLTALWEQALNQIAE  M+L+ FMQKQE FV 
Sbjct  541  LLKKKKSLVASAEAVALIDSLPDLLKNPGLTALWEQALNQIAEGSMTLDAFMQKQEAFVK  600

Query  597  HLIQTCGHQGIKMGNIDIKKCPQCGKPLRKMKGKNGDFLGCTGYPKCKYIESGAKRKTSA  656
            +LI +C +QG+ +GNI+I+KC++CGKP+RK++  +G F GCTGYP C+  E++ K K+++
Sbjct  601  QLIGSCMQQGMSLGNIEIRKCSECGKPMRKINHAKGTFWGCTGYPDCQHKEADKKVKSAS  660

Query  657  G----KVTPINLSQQFANLR  672
                 K + +N+ +Q+ +LR
Sbjct  661  NKSAKKSSNLNVLDQLNKLR  680

> NC_016808_R1|63|G56|378773985|YP_005176228.1|Pasteurella_multocida_36950|-|54272..56323|topB1|Pmu_03290|DNA 
topoisomerase 
III
Length=683

 Score =  642 bits (2426),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 360/648 (56%), Positives = 499/648 (78%), Gaps = 13/648 (2%)

Query  1    MKLILCEKPSQGRDIGKFIGATKRGEGYLSSPDQQTFVTWGIGHLVEQAEPQDYDESYKK  60
            MKL++CEKPSQ+RD++  +GAT +GEG L+++D+  +VTWG+GHLVEQ +P+DYDE+ K+
Sbjct  1    MKLFICEKPSQARDLAGVLGATSKGEGLLATADKSIIVTWGFGHLVEQYQPEDYDEAWKR  60

Query  61   WIFDNLPIIPDKWIMKVKKETAKQYKIVMGLIKKANHIVIATDPDREGEVIARELLDMAN  120
            W F+ LPIIP +W M  KKE+ KQY +V+GLIKKA  +VIATD+DREGE+IARELLD+A 
Sbjct  61   WAFETLPIIPAQWKMTPKKESKKQYSVVIGLIKKATSVVIATDADREGEMIARELLDLAG  120

Query  121  YKGKVQRLWLSALDDGSIRKALANLKSDAETKPLYAAGLARGRADWLVGMNLTRLFTLIA  180
            Y+G++QR WLSALDD+SIRKAL  LKS+ ET +LY AG++R+R+DWL+GMN++RLFTL+A
Sbjct  121  YRGQIQRCWLSALDDASIRKALQTLKSGKETEALYYAGMGRSRSDWLIGMNFSRLFTLMA  180

Query  181  QKQGYQG-VMSVGRVQSPTLAIVVQRDREIENFVSKPFYRLKVNL-----DGFCAYWQPT  234
            Q +GY G  +SVGRVQSPTL++VV+RDREI NFV+K+ Y L V+L     + F A     
Sbjct  181  QAKGYSGKPLSVGRVQSPTLTLVVNRDREIANFVPKSHYALAVQLTTTSGETFVAGLAVP  240

Query  235  ESVCDDEGRCIDYSVITQVQRQLSKT--LKIDNIETKRKKEMPPLAFDLGTLQQTCSRLF  292
            E   D+ G C+D  VI Q + Q+ +T   K+  +ETKR K  PPL + L+ LQ  C+RLF
Sbjct  241  EQYLDESGLCLDSRVIQQAEAQIKQTGLAKVVTVETKREKKSPPLLYALSDLQGECNRLF  300

Query  293  GMGAAQVLKIAQSLYETHKATTYPRTDCGYLPESMIDEIPLVLKAVSESDPQVRNIVAKL  352
            G GA QVL IAQSLYE HK TTYPRTDCGYLPES + ++P V++++  SD+ ++ +++KL
Sbjct  301  GFGAQQVLDIAQSLYEEHKITTYPRTDCGYLPESQFSDVPNVIRSLVASDSGLQTLLPKL  360

Query  353  DISLRSRVWNDSKITAHHGIIPTTQKVDLSKMSDDELKVYQLVRKHYFAQFLPLYEEDNT  412
            ++  +SR W+D KITAHHGIIPT +K DLSK+S++E+KVY+L+R++Y+AQFLP  E D+T
Sbjct  361  NLRQKSRAWDDKKITAHHGIIPTIKKADLSKLSEEEMKVYDLIRRRYLAQFLPHLEMDKT  420

Query  413  SVLLSGNEQTFVSKGKQVIKIGWKSLF----QQDRNEDDEEQSLPSLRQGQSCNVVDSEV  468
               L ++ +T+V++G+ ++  GW+ LF    +++  +DDE Q+LP L + Q CNV +SEV
Sbjct  421  VATLQSSGHTLVARGNVIVAQGWRILFGKNVDEETGNDDEKQGLPVLTKNQQCNVTHSEV  480

Query  469  LTLKTTPPKHYTEGTLIAAMKNAARFVTDARLKQRLRETEGLGTEATRAEVIETLFKRGY  528
             TL+T PP HYTEGTL+ AMKNAARFVTD+RLKQRLRETEGLGTEATRA +I+ L+ +G+
Sbjct  481  RTLQTKPPAHYTEGTLLDAMKNAARFVTDPRLKQRLRETEGLGTEATRAGLIQGLIDKGF  540

Query  529  LEKKRKEIVATSAGRSLIDGLPDIIKDPGMTALWEQALNDIASGKMLLQDFMAKQNQFIS  588
            L KK+K +VA++ + +LID+LPD++K+PG+TALWEQALN+IA G M L+ FM KQ+ F+ 
Sbjct  541  LLKKKKSLVASAEAVALIDSLPDLLKNPGLTALWEQALNQIAEGSMTLDAFMQKQEAFVK  600

Query  589  HVVKSMIGSGSVAIQVKAEKICPKCGAAMRRRKGKNGDFWGCSNYPTC  636
            +++ S +  G    ++   K C+ CG +MR+ +  +G FWGC+ YP C
Sbjct  601  QLIGSCMQQGMSLGNIEIRK-CSECGKPMRKINHAKGTFWGCTGYPDC  647

> NC_016808_R1|63|G56|378773985|YP_005176228.1|Pasteurella_multocida_36950|-|54272..56323|topB1|Pmu_03290|DNA 
topoisomerase 
III
Length=683

 Score =  602 bits (2273),  Expect = 3e-173, Method: Compositional matrix adjust.
 Identities = 332/669 (50%), Positives = 493/669 (74%), Gaps = 6/669 (0%)

Query  1    MRVFLCEKPSQGKDIARVLGAGQRGNG--CYSGASVVVTWCIGHLVEAVPPEGYGEQYKR  58
            M++F+CEKPSQ++D+A VLGA  +G+G    ++ S++VTW +GHLVE   PE+Y+E  KR
Sbjct  1    MKLFICEKPSQARDLAGVLGATSKGEGLLATADKSIIVTWGFGHLVEQYQPEDYDEAWKR  60

Query  59   WAIEQLPIVPERWRVEPKAATVAQFKVVQQLVAKAGELVIATDADREGEMIAREIIDLCG  118
            WA+E LPI+P +W++ PK  +  Q+ VV  L+ KA  +VIATDADREGEMIARE++DL G
Sbjct  61   WAFETLPIIPAQWKMTPKKESKKQYSVVIGLIKKATSVVIATDADREGEMIARELLDLAG  120

Query  119  YRGPIQRLWLSALNDASIRKALGALKPSAETMPLYFSALARSRADWLIGMNLSRLFTLLG  178
            YRG IQR WLSAL+DASIRKAL +LK++ ET +LY+++++RSR+DWLIGMN+SRLFTL++
Sbjct  121  YRGQIQRCWLSALDDASIRKALQTLKSGKETEALYYAGMGRSRSDWLIGMNFSRLFTLMA  180

Query  179  RQAGYNG-VLSVGRVQTPTLKLVVDRDREIARFVSVPFWATEVALSHA-GQTFVASWTPP  236
            +  GY+G  LSVGRVQ+PTL LVV+RDREIA FV+ +  A  V L+ + G+TFVA+ + P
Sbjct  181  QAKGYSGKPLSVGRVQSPTLTLVVNRDREIANFVPKSHYALAVQLTTTSGETFVAGLAVP  240

Query  237  QGSTDEAGRCLRQPVAQQAAERLRAAGTAQVLSVETERVREGPPLPFDLGTLQEVCSKQL  296
            +   DE+G CL   V QQA  +++ +G A+V++VET R + +PPL + L+ LQ  C++ +
Sbjct  241  EQYLDESGLCLDSRVIQQAEAQIKQTGLAKVVTVETKREKKSPPLLYALSDLQGECNRLF  300

Query  297  GLDVQETLDIAQALYETHKATTYPRSDSGHLPESMLAEVPAVLDSLVKTDPSLRPLIDRL  356
            G++ Q+ LDIAQ+LYE HK TTYPR+D G LPES +++VP V+ SLV +D++L+ L+ +L
Sbjct  301  GFGAQQVLDIAQSLYEEHKITTYPRTDCGYLPESQFSDVPNVIRSLVASDSGLQTLLPKL  360

Query  357  DRQQRSRAWNDGKVTAHHGIIPTLEPANLSAMTEKELAVYRLIRAHYLAQFLPHHEFDRT  416
            + +Q+SRAW+D K+TAHHGIIPT+  A+LS ++E E+ VY LIR +YLAQFLPH E D+T
Sbjct  361  NLRQKSRAWDDKKITAHHGIIPTIKKADLSKLSEEEMKVYDLIRRRYLAQFLPHLEMDKT  420

Query  417  VAQLTCGGQSLVAVGKQIATAGWRQVLAAPALDDTDGEDARRGQVLPALKAGDACQVSQV  476
            VA L  +G++LVA G+ I + GWR +++    ++T+ +D ++G  LP L   + C+V++ 
Sbjct  421  VATLQSSGHTLVARGNVIVAQGWRILFGKNVDEETGNDDEKQG--LPVLTKNQQCNVTHS  478

Query  477  ELKALKTLPPKPYTQGELVKAMKGVAKLVTDPRLKQKLKDTTGIGTEATRANIISGLLAR  536
            E+++L+T PP  YT+G L+ AMK  A++VTDPRLKQ+L++T G+GTEATRA +I GL+ +
Sbjct  479  EVRTLQTKPPAHYTEGTLLDAMKNAARFVTDPRLKQRLRETEGLGTEATRAGLIQGLIDK  538

Query  537  GYLLKKGRAIRASDAAFTLIDAVPAAIADPGTTAVWEHALDMIEAGQMALDTFIAKQSSW  596
            G+LLKK +++ AS  A +LID++P  + +PG TA+WE+AL+ I  G M+LD+F+ KQ + 
Sbjct  539  GFLLKKKKSLVASAEAVALIDSLPDLLKNPGLTALWEQALNQIAEGSMTLDAFMQKQEAF  598

Query  597  VARLVQQYRGATLDLKLPPAPDCPQCGAPMRQRSSKSGVFWSCSRYPDCKGTQPVEDAAA  656
            V +L+       + L       C++CG PMR+ +   G FW+C+ YPDC+  ++     +
Sbjct  599  VKQLIGSCMQQGMSLGNIEIRKCSECGKPMRKINHAKGTFWGCTGYPDCQHKEADKKVKS  658

Query  657  GKRGASSRT  665
            +   ++ ++
Sbjct  659  ASNKSAKKS  667

> NC_016808_R1|63|G56|378773985|YP_005176228.1|Pasteurella_multocida_36950|-|54272..56323|topB1|Pmu_03290|DNA 
topoisomerase 
III
Length=683

 Score =  589 bits (2225),  Expect = 2e-169, Method: Compositional matrix adjust.
 Identities = 339/674 (51%), Positives = 491/674 (73%), Gaps = 10/674 (1%)

Query  1    MRLFLCEKPSQGKDIGRILGATQRGEGCLNGS--GVTVTWCIGHLVEAAAPEVYDAALKR  58
            M+LF+CEKPSQ++D++ +LGAT +GEG L  +  ++ VTW +GHLVE   PE YD A KR
Sbjct  1    MKLFICEKPSQARDLAGVLGATSKGEGLLATADKSIIVTWGFGHLVEQYQPEDYDEAWKR  60

Query  59   WSLEQLPIIPQQWRVEVKPQTATQFKVVKTLLAKATHLVIATDADREGELIAREIIDLCG  118
            W++E LPIIP QW++  K ++  Q+ VV  L+ KAT +VIATDADREGE+IARE++DL G
Sbjct  61   WAFETLPIIPAQWKMTPKKESKKQYSVVIGLIKKATSVVIATDADREGEMIARELLDLAG  120

Query  119  YRGPIARLWLSALNDASIRTALAKLRPSAETLPMYYSALARSRADWLVGMNLSRLFTVLG  178
            YRG I R WLSAL+DASIR AL  L+++ ET ++YY++++RSR+DWL+GMN+SRLFT+++
Sbjct  121  YRGQIQRCWLSALDDASIRKALQTLKSGKETEALYYAGMGRSRSDWLIGMNFSRLFTLMA  180

Query  179  RQAGYDG-VLSVGRVQTPTLKLVVDRDREIAAFVSVPYWAIDVSLSA-GGQTFTAQWVAP  236
            +  GY G  LSVGRVQ+PTL LVV+RDREIA FV+ +  A+ V L++ +G+TF A    P
Sbjct  181  QAKGYSGKPLSVGRVQSPTLTLVVNRDREIANFVPKSHYALAVQLTTTSGETFVAGLAVP  240

Query  237  DASTDDAGRCLqqpvaqqaaqqiraagsaqVVSVETERVREGPPLLFDLGTLQEVCSKQL  296
            +   D++G CL+  V QQA  QI+ +G A+VV+VET R + +PPLL+ L+ LQ  C++ +
Sbjct  241  EQYLDESGLCLDSRVIQQAEAQIKQTGLAKVVTVETKREKKSPPLLYALSDLQGECNRLF  300

Query  297  GLDVQETLEIAQALYETHKATTYPRSDSGYLPESMFAEVPTVLDSLLKTDPTLAPIMGQL  356
            G++ Q+ L+IAQ+LYE HK TTYPR+D GYLPES F++VP V+ SL+ +D+ L  ++ +L
Sbjct  301  GFGAQQVLDIAQSLYEEHKITTYPRTDCGYLPESQFSDVPNVIRSLVASDSGLQTLLPKL  360

Query  357  DRAQRSRAWNDSKVTAHHGIIPTLEPANLSAMSEKEQAVYRLIRAHYLAQFLPHHEFDRT  416
            +  Q+SRAW+D K+TAHHGIIPT+  A+LS +SE E  VY LIR +YLAQFLPH E D+T
Sbjct  361  NLRQKSRAWDDKKITAHHGIIPTIKKADLSKLSEEEMKVYDLIRRRYLAQFLPHLEMDKT  420

Query  417  IAELSCGQQKLVATGKQVAAQGWHLVLAEPQADEDGETIARSQVLPALREGLACQVAEAE  476
            +A L  + + LVA G+ + AQGW+++++    +E G+   + Q LP L     C+V+++E
Sbjct  421  VATLQSSGHTLVARGNVIVAQGWRILFGKNVDEETGNDDEK-QGLPVLTKNQQCNVTHSE  479

Query  477  VKALKTLPPKPYTQGELVKSMKGVARFVTDPRLKQKLKDTTGIGTEATRANIITGLLTRG  536
            V++L+T PP  YT+G L+ +MK  ARFVTDPRLKQ+L++T G+GTEATRA +I GL+ +G
Sbjct  480  VRTLQTKPPAHYTEGTLLDAMKNAARFVTDPRLKQRLRETEGLGTEATRAGLIQGLIDKG  539

Query  537  YLVKKGRSIRASDAALTLIDAVPAAIADPGTTAVWEQALDMIEAGQLTLDVFIGKQAAWI  596
            +L+KK +S+ AS  A++LID++P  + +PG TA+WEQAL+ I  G +TLD F+ KQ A +
Sbjct  540  FLLKKKKSLVASAEAVALIDSLPDLLKNPGLTALWEQALNQIAEGSMTLDAFMQKQEAFV  599

Query  597  SQLIAQYGSTSLSIKVPQGPACPQCGAPTRQRTGKSGPFWSCSRYPDCKGTLPVETGTSK  656
             QLI+     ++S+   +   C++CG P R+     G FW+C+ YPDC+     +  + K
Sbjct  600  KQLIGSCMQQGMSLGNIEIRKCSECGKPMRKINHAKGTFWGCTGYPDCQ-----HKEADK  654

Query  657  RGASRPRKSGRKGS  670
            +  S + KS++K+S
Sbjct  655  KVKSASNKSAKKSS  668

> NC_016808_R1|63|G56|378773985|YP_005176228.1|Pasteurella_multocida_36950|-|54272..56323|topB1|Pmu_03290|DNA 
topoisomerase 
III
Length=683

 Score =  589 bits (2224),  Expect = 2e-169, Method: Compositional matrix adjust.
 Identities = 339/674 (51%), Positives = 490/674 (73%), Gaps = 10/674 (1%)

Query  1    MRLFLCEKPSQGKDIGRILGATQRGEGCLNGS--GVTVTWCIGHLVEAAAPEVYDAALKR  58
            M+LF+CEKPSQ++D++ +LGAT +GEG L  +  ++ VTW +GHLVE   PE YD A KR
Sbjct  1    MKLFICEKPSQARDLAGVLGATSKGEGLLATADKSIIVTWGFGHLVEQYQPEDYDEAWKR  60

Query  59   WSLEQLPIIPQQWRVEVKPQTATQFKVVKTLLAKATHLVIATDADREGELIAREIIDLCG  118
            W++E LPIIP QW++  K ++  Q+ VV  L+ KAT +VIATDADREGE+IARE++DL G
Sbjct  61   WAFETLPIIPAQWKMTPKKESKKQYSVVIGLIKKATSVVIATDADREGEMIARELLDLAG  120

Query  119  YRGPIARLWLSALNDASIRTALAKLRPSAETLPMYYSALARSRADWLVGMNLSRLFTVLG  178
            YRG I R WLSAL+DASIR AL  L+++ ET ++YY++++RSR+DWL+GMN+SRLFT+++
Sbjct  121  YRGQIQRCWLSALDDASIRKALQTLKSGKETEALYYAGMGRSRSDWLIGMNFSRLFTLMA  180

Query  179  RQAGYDG-VLSVGRVQTPTLKLVVDRDREIAAFVSVPYWAIDVSLSA-GGQTFTAQWVAP  236
            +  GY G  LSVGRVQ+PTL LVV+RDREIA FV+ +  A+ V L++ +G+TF A    P
Sbjct  181  QAKGYSGKPLSVGRVQSPTLTLVVNRDREIANFVPKSHYALAVQLTTTSGETFVAGLAVP  240

Query  237  DASTDDAGRCLqqpvaqqaaqqiraagsaqVVSVETERVREGPPLLFDLGTLQEVCSKQL  296
            +   D++G CL+  V QQA  QI+ +G A+VV+VET R + +PPLL+ L+ LQ  C++ +
Sbjct  241  EQYLDESGLCLDSRVIQQAEAQIKQTGLAKVVTVETKREKKSPPLLYALSDLQGECNRLF  300

Query  297  GLDVQETLEIAQALYETHKATTYPRSDSGYLPESMFAEVPTVLDSLLKTDPTLAPIMGQL  356
            G++ Q+ L+IAQ+LYE HK TTYPR+D GYLPES F++VP V+ SL+ +D+ L  ++ +L
Sbjct  301  GFGAQQVLDIAQSLYEEHKITTYPRTDCGYLPESQFSDVPNVIRSLVASDSGLQTLLPKL  360

Query  357  DRAQRSRAWNDSKVTAHHGIIPTLEPANLSAMSEKEQAVYRLIRAHYLAQFLPHHEFDRT  416
            +  Q+SRAW+D K+TAHHGIIPT+  A+LS +SE E  VY LIR +YLAQFLPH E D+T
Sbjct  361  NLRQKSRAWDDKKITAHHGIIPTIKKADLSKLSEEEMKVYDLIRRRYLAQFLPHLEMDKT  420

Query  417  IAELSCGQQKLVATGKQVAAQGWHLVLAEPQADEDGETTARSQVLPALREGLACQVAEAE  476
            +A L  + + LVA G+ + AQGW+++++    +E G+   + Q LP L     C+V+++E
Sbjct  421  VATLQSSGHTLVARGNVIVAQGWRILFGKNVDEETGNDDEK-QGLPVLTKNQQCNVTHSE  479

Query  477  VKALKTLPPKPYTQGELVKSMKGVARFVTDPRLKQKLKDTTGIGTEATRANIITGLLTRG  536
            V++L+T PP  YT+G L+ +MK  ARFVTDPRLKQ+L++T G+GTEATRA +I GL+ +G
Sbjct  480  VRTLQTKPPAHYTEGTLLDAMKNAARFVTDPRLKQRLRETEGLGTEATRAGLIQGLIDKG  539

Query  537  YLVKKGRSIRASDAALTLIDAVPAAIADPGTTAVWEQALDMIEAGQLTLDVFIGKQAAWI  596
            +L+KK +S+ AS  A++LID++P  + +PG TA+WEQAL+ I  G +TLD F+ KQ A +
Sbjct  540  FLLKKKKSLVASAEAVALIDSLPDLLKNPGLTALWEQALNQIAEGSMTLDAFMQKQEAFV  599

Query  597  SQLIVQYGSTSLSIKVPQGPACPQCGAPTRQRTGKTGPFWSCSRYPDCKGTLPVETGTSK  656
             QLI      ++S+   +   C++CG P R+     G FW+C+ YPDC+     +  + K
Sbjct  600  KQLIGSCMQQGMSLGNIEIRKCSECGKPMRKINHAKGTFWGCTGYPDCQ-----HKEADK  654

Query  657  RGASRPRKSGRKGS  670
            +  S + KS++K+S
Sbjct  655  KVKSASNKSAKKSS  668

> NC_016808_R1|63|G56|378773985|YP_005176228.1|Pasteurella_multocida_36950|-|54272..56323|topB1|Pmu_03290|DNA 
topoisomerase 
III
Length=683

 Score =  589 bits (2223),  Expect = 3e-169, Method: Compositional matrix adjust.
 Identities = 340/677 (51%), Positives = 493/677 (73%), Gaps = 13/677 (1%)

Query  1    MRVFLCEKPSQGKDIARVLGAGQRRNG--CYSGAGIVVTWCIGHLVEAVPPEGYDERDKR  58
            M++F+CEKPSQ++D+A VLGA  + +G    ++ +I+VTW +GHLVE   PE+YDE  KR
Sbjct  1    MKLFICEKPSQARDLAGVLGATSKGEGLLATADKSIIVTWGFGHLVEQYQPEDYDEAWKR  60

Query  59   WVIEQLPIIPERWRVEPKAATAAQFKIVKQLVGQATELVIATDADREGEMIAREIIELCG  118
            W +E LPIIP +W++ PK  +  Q+ +V  L+ +AT +VIATDADREGEMIARE+++L G
Sbjct  61   WAFETLPIIPAQWKMTPKKESKKQYSVVIGLIKKATSVVIATDADREGEMIARELLDLAG  120

Query  119  YRGAIQRLWLSALNDASIRKALGALKSSAETLPLYYSALARSRADWLIGMNLSRLFTLLG  178
            YRG IQR WLSAL+DASIRKAL +LKS+ ET +LYY++++RSR+DWLIGMN+SRLFTL++
Sbjct  121  YRGQIQRCWLSALDDASIRKALQTLKSGKETEALYYAGMGRSRSDWLIGMNFSRLFTLMA  180

Query  179  RQAGYTG-VLSVGRVQTPTLKLVVDRDREIARFVSAPFWAVEVALSHA-GQPFTASWTPP  236
            +  GY+G  LSVGRVQ+PTL LVV+RDREIA FV+ +  A+ V L+ + G+ F A+ + P
Sbjct  181  QAKGYSGKPLSVGRVQSPTLTLVVNRDREIANFVPKSHYALAVQLTTTSGETFVAGLAVP  240

Query  237  EGCTDEAGRCLQQPVAQQAAERMRATGSAQVASVETERVREGPPLPFDLGTLQELCSQQL  296
            E   DE+G CL+  V QQA  +++ TG A+V +VET R + +PPL + L+ LQ  C++ +
Sbjct  241  EQYLDESGLCLDSRVIQQAEAQIKQTGLAKVVTVETKREKKSPPLLYALSDLQGECNRLF  300

Query  297  GLDVQETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPTVLDSLVKTDPSLRPLIDRL  356
            G++ Q+ LDIAQ+LYE HK TTYPR+D GYLPES +++VP V+ SLV +D++L+ L+ +L
Sbjct  301  GFGAQQVLDIAQSLYEEHKITTYPRTDCGYLPESQFSDVPNVIRSLVASDSGLQTLLPKL  360

Query  357  DRNQRSRAWSDAKVTAHHGIIPTLEPANLSAMNDKELAVYKLIRAHYLAQFLPHHEFDRT  416
            +  Q+SRAW D K+TAHHGIIPT+  A+LS +++ E+ VY LIR +YLAQFLPH E D+T
Sbjct  361  NLRQKSRAWDDKKITAHHGIIPTIKKADLSKLSEEEMKVYDLIRRRYLAQFLPHLEMDKT  420

Query  417  VAELACGGQSLLAVGKQIAVAGWRQVLASSEEGGADSDDAQRSQVLPALRAGLSCQVGHV  476
            VA L  +G++L+A G+ I   GWR +++ + +  +++DD +  Q LP L     C+V H 
Sbjct  421  VATLQSSGHTLVARGNVIVAQGWRILFGKNVDEETGNDDEK--QGLPVLTKNQQCNVTHS  478

Query  477  DLKALKTLPPKPYTQGELVKAMKGVARLVTDPRLKQKLKDTTGIGTEATRANIISGLLGR  536
            ++++L+T PP  YT+G L+ AMK  AR+VTDPRLKQ+L++T G+GTEATRA +I GL+++
Sbjct  479  EVRTLQTKPPAHYTEGTLLDAMKNAARFVTDPRLKQRLRETEGLGTEATRAGLIQGLIDK  538

Query  537  GYLLTKGRAVRASDAAFTLIDTVPAAIADPGTTAVWEQALDMIEAGQMTLDAFIAKQSAW  596
            G+LL K +++ AS  A +LID++P  + +PG TA+WEQAL+ I  G MTLDAF+ KQ A 
Sbjct  539  GFLLKKKKSLVASAEAVALIDSLPDLLKNPGLTALWEQALNQIAEGSMTLDAFMQKQEAF  598

Query  597  VTQLVQQYRGTTLAIKLppspspscpQCGAPMRQRTGKSGAFWSCSRYPDCKGTLPVDTS  656
            V QL+       ++  L       C++CG PMR+     G+FW+C+ YPDC+     +  
Sbjct  599  VKQLIGSCMQQGMS--LGNIEIRKCSECGKPMRKINHAKGTFWGCTGYPDCQ-----HKE  651

Query  657  TGKRSASRKQRASPKAS  673
            ++K+  S  ++++ K+S
Sbjct  652  ADKKVKSASNKSAKKSS  668

> NC_016808_R1|63|G56|378773985|YP_005176228.1|Pasteurella_multocida_36950|-|54272..56323|topB1|Pmu_03290|DNA 
topoisomerase 
III
Length=683

 Score =  588 bits (2221),  Expect = 4e-169, Method: Compositional matrix adjust.
 Identities = 338/674 (51%), Positives = 495/674 (74%), Gaps = 10/674 (1%)

Query  1    MRLFLCEKPSQGKDIGRILGATQRGEGCLSGS--GVIVTWCIGHLVEAAAPEVYDAALKR  58
            M+LF+CEKPSQ++D++ +LGAT +GEG L+ +  ++IVTW +GHLVE   PE YD A KR
Sbjct  1    MKLFICEKPSQARDLAGVLGATSKGEGLLATADKSIIVTWGFGHLVEQYQPEDYDEAWKR  60

Query  59   WSLEQLPIIPQQWRVEVKPKTATQFKVVKALLAKATHLVIATDADREGELIAREIIDLCG  118
            W++E LPIIP QW++  K  +  Q+ VV +L+ KAT +VIATDADREGE+IARE++DL G
Sbjct  61   WAFETLPIIPAQWKMTPKKESKKQYSVVIGLIKKATSVVIATDADREGEMIARELLDLAG  120

Query  119  YRGPIERLWLSALNDASIRTALGKLRPSSDTLPMYYSAQARSRADWLVGMNLSRLFTVLG  178
            YRG I+R WLSAL+DASIR AL  L+++ +T ++YY++ +RSR+DWL+GMN+SRLFT+++
Sbjct  121  YRGQIQRCWLSALDDASIRKALQTLKSGKETEALYYAGMGRSRSDWLIGMNFSRLFTLMA  180

Query  179  RQAGYDG-VLSVGRVQTPTLKLVVDRDREIAAFKSVPFWAIDVSLSA-GGQAFSAQWVPP  236
            +  GY G  LSVGRVQ+PTL LVV+RDREIA F + +  A+ V L++ +G++F A    P
Sbjct  181  QAKGYSGKPLSVGRVQSPTLTLVVNRDREIANFVPKSHYALAVQLTTTSGETFVAGLAVP  240

Query  237  DGCIDDAGRCLqqpvaqqaaqqiraagsaqVVSVETKRVREGPPLLFDLGTLQEVCSKQL  296
            +  +D++G CL+  V QQA  QI+ +G A+VV+VETKR + +PPLL+ L+ LQ  C++ +
Sbjct  241  EQYLDESGLCLDSRVIQQAEAQIKQTGLAKVVTVETKREKKSPPLLYALSDLQGECNRLF  300

Query  297  GLDVQETLEIAQALYETHKATTYPRSDSGYLPESMFAEVPTVLDSLLKTDPSLRPIMGQL  356
            G++ Q+ L+IAQ+LYE HK TTYPR+D GYLPES F++VP V+ SL+ +D++L+ ++ +L
Sbjct  301  GFGAQQVLDIAQSLYEEHKITTYPRTDCGYLPESQFSDVPNVIRSLVASDSGLQTLLPKL  360

Query  357  DRSQRSRAWNDGKVTAHHGIIPTLEPANLSVMSEKELAVYRLIRAHYLAQFLPHHEFDRT  416
            +  Q+SRAW+D K+TAHHGIIPT+  A+LS +SE E+ VY LIR +YLAQFLPH E D+T
Sbjct  361  NLRQKSRAWDDKKITAHHGIIPTIKKADLSKLSEEEMKVYDLIRRRYLAQFLPHLEMDKT  420

Query  417  VAELSCGQQKLAATGKQVVAQGWRLVLAEPQADEDGDDAARSQVLPALREGMACQVAEAE  476
            VA L  + + L A G+ +VAQGWR++++    +E G+D  + Q LP L     C+V+++E
Sbjct  421  VATLQSSGHTLVARGNVIVAQGWRILFGKNVDEETGNDDEK-QGLPVLTKNQQCNVTHSE  479

Query  477  IKALKTMPPKPYTQGELVKSMKGVAKLVTDPRLKQKLKETVGIGTEATRANIISGLIARG  536
            +++L+T PP  YT+G L+ +MK  A++VTDPRLKQ+L+ET G+GTEATRA +I GLI +G
Sbjct  480  VRTLQTKPPAHYTEGTLLDAMKNAARFVTDPRLKQRLRETEGLGTEATRAGLIQGLIDKG  539

Query  537  YLVKKGRSIRASDAAFTLIDAVPTAIADPGTTAVWEQALDMIEAGQLTLDVFIGKQAAWI  596
            +L+KK +S+ AS  A +LID++P  + +PG TA+WEQAL+ I  G +TLD F+ KQ A +
Sbjct  540  FLLKKKKSLVASAEAVALIDSLPDLLKNPGLTALWEQALNQIAEGSMTLDAFMQKQEAFV  599

Query  597  SQLIAQYGSTSLSIKVPQGPACPQCGATTRQRTGKTGPFWSCSRYPDCKGTLPVDSGTSK  656
             QLI+     ++S+   +   C++CG   R+     G FW+C+ YPDC+     +  + K
Sbjct  600  KQLIGSCMQQGMSLGNIEIRKCSECGKPMRKINHAKGTFWGCTGYPDCQ-----HKEADK  654

Query  657  RGASRPRTSGRKGS  670
            +  S +  S++K+S
Sbjct  655  KVKSASNKSAKKSS  668

> NC_016808_R1|63|G56|378773985|YP_005176228.1|Pasteurella_multocida_36950|-|54272..56323|topB1|Pmu_03290|DNA 
topoisomerase 
III
Length=683

 Score =  587 bits (2216),  Expect = 1e-168, Method: Compositional matrix adjust.
 Identities = 321/670 (48%), Positives = 486/670 (73%), Gaps = 5/670 (0%)

Query  1    MKLFLCEKPSQGKDIGRVLGATQRGKGCLTGS--GITITWCIGHLVEAAPPDAYGEQYKR  58
            MKLF+CEKPSQ++D++ VLGAT +G G L+ +  +I +TW +GHLVE   P+ Y+E  KR
Sbjct  1    MKLFICEKPSQARDLAGVLGATSKGEGLLATADKSIIVTWGFGHLVEQYQPEDYDEAWKR  60

Query  59   WSIEQLPIIPERWRVDVKSKTASQFNVVKDLLSKASELVIATDADREGELIAREIIELCG  118
            W++E LPIIP +W++  K  +  Q++VV +L+ KA+ +VIATDADREGE+IARE+++L G
Sbjct  61   WAFETLPIIPAQWKMTPKKESKKQYSVVIGLIKKATSVVIATDADREGEMIARELLDLAG  120

Query  119  YRGPIQRLWLSALNDASIRKALATLRPSSETLPMYFSALARSRADWLIGMNLSRLFTVMG  178
            YRG IQR WLSAL+DASIRKAL TL+++ ET ++Y+++++RSR+DWLIGMN+SRLFT+M+
Sbjct  121  YRGQIQRCWLSALDDASIRKALQTLKSGKETEALYYAGMGRSRSDWLIGMNFSRLFTLMA  180

Query  179  RQAGYDG-VLSVGRVQTPTLKLVVDRDREIACFVSVPFWAVETTLSS-EGQSFTAAWLAP  236
            +  GY G  LSVGRVQ+PTL LVV+RDREIA FV+ +  A+   L++  G++F A+   P
Sbjct  181  QAKGYSGKPLSVGRVQSPTLTLVVNRDREIANFVPKSHYALAVQLTTTSGETFVAGLAVP  240

Query  237  DTATDDAGRCLQESIARQAVERMRSAGSAQITSVETERMREGPPLPFDLGTLQEICSKQL  296
            +   D++G CL+  + +QA  +++ +G A++ +VET R + +PPL + L+ LQ  C++ +
Sbjct  241  EQYLDESGLCLDSRVIQQAEAQIKQTGLAKVVTVETKREKKSPPLLYALSDLQGECNRLF  300

Query  297  GLDVQETLEIAQALYETHKATTYPRSDSGYLPDSMFAEVPTVLDSLLKTDPGLRPLVDQL  356
            G++ Q+ L+IAQ+LYE HK TTYPR+D GYLP+S F++VP V+ SL+ +D+GL+ L+ +L
Sbjct  301  GFGAQQVLDIAQSLYEEHKITTYPRTDCGYLPESQFSDVPNVIRSLVASDSGLQTLLPKL  360

Query  357  DRNQRSRAWNDSKVTAHHGIIPTLEPANLKAMNDKERAVYMLIRAHYLAQFLPQHEFDRT  416
            +  Q+SRAW+D K+TAHHGIIPT+  A+L  +++ E  VY LIR +YLAQFLP+ E D+T
Sbjct  361  NLRQKSRAWDDKKITAHHGIIPTIKKADLSKLSEEEMKVYDLIRRRYLAQFLPHLEMDKT  420

Query  417  TARLSCAGETLQAVGKQVVVIGWRQVLAEPRPDDDGETTPRSQVLPALHEGLSCQITGID  476
             A L  +G+TL A G+ +V  GWR +++    ++ G+   + Q LP L     C++T  +
Sbjct  421  VATLQSSGHTLVARGNVIVAQGWRILFGKNVDEETGNDDEK-QGLPVLTKNQQCNVTHSE  479

Query  477  CKALKTSPPRPYTQGELVKAMKGVAKLVADPRLKQKLKDTTGIGTEATRANIIKGLLDRG  536
             ++L+T PP  YT+G L+ AMK  A++V+DPRLKQ+L++T G+GTEATRA +I+GL+D+G
Sbjct  480  VRTLQTKPPAHYTEGTLLDAMKNAARFVTDPRLKQRLRETEGLGTEATRAGLIQGLIDKG  539

Query  537  YLQKKGRSVRASDAAFTLIDVVPGAIADPGMTAIWEQALDMIEAGQLTLDVFIDKQSAWI  596
            +L KK +S+ AS  A +LID +P+ + +PG+TA+WEQAL+ I  G +TLD F++KQ A +
Sbjct  540  FLLKKKKSLVASAEAVALIDSLPDLLKNPGLTALWEQALNQIAEGSMTLDAFMQKQEAFV  599

Query  597  TQLVQQYQGASLSIKVPQGPACPECGTAMRQRTGKSGPFWSCPRYPDCKGSQPIDNGKHK  656
             QL+      ++S+   +   C+ECG +MR+     G FW+C  YPDC+  ++  + K  
Sbjct  600  KQLIGSCMQQGMSLGNIEIRKCSECGKPMRKINHAKGTFWGCTGYPDCQHKEADKKVKSA  659

Query  657  RAMPRKRNSS  666
               + K++S+
Sbjct  660  SNKSAKKSSN  669

> NC_016808_R1|63|G56|378773985|YP_005176228.1|Pasteurella_multocida_36950|-|54272..56323|topB1|Pmu_03290|DNA 
topoisomerase 
III
Length=683

 Score =  586 bits (2214),  Expect = 1e-168, Method: Compositional matrix adjust.
 Identities = 332/650 (52%), Positives = 476/650 (74%), Gaps = 6/650 (0%)

Query  1    MRVFLCEKPSQGKDIARVLGAGQRGNGYYSGA--GVVVTWCIGHLVEAVPPEGYGEQYKR  58
            M++F+CEKPSQ++D+A VLGA  +G+G  + A  +++VTW +GHLVE   PE+Y+E  KR
Sbjct  1    MKLFICEKPSQARDLAGVLGATSKGEGLLATADKSIIVTWGFGHLVEQYQPEDYDEAWKR  60

Query  59   WAIEQLPILPERWRVEPKAATAAQFKVVQQLVAKAGELVIATDADREGEMIAREIIDLCG  118
            WA+E LPI+P +W++ PK  +  Q+ VV  L+ KA  +VIATDADREGEMIARE++DL G
Sbjct  61   WAFETLPIIPAQWKMTPKKESKKQYSVVIGLIKKATSVVIATDADREGEMIARELLDLAG  120

Query  119  YHGPIQRLWLSALNDASIRKALGALKPSAETLPLYYSALARSRADWLIGMNLSRLFTLLG  178
            Y+G IQR WLSAL+DASIRKAL +LK++ ET +LYY++++RSR+DWLIGMN+SRLFTL++
Sbjct  121  YRGQIQRCWLSALDDASIRKALQTLKSGKETEALYYAGMGRSRSDWLIGMNFSRLFTLMA  180

Query  179  RQAGYTG-VLSVGRVQTPTLKLVVDRDREIARFVSVPYWAVDV-LLSHAGRSFTASWIPP  236
            +  GY+G  LSVGRVQ+PTL LVV+RDREIA FV+ +  A+ V L + +G +F A+   P
Sbjct  181  QAKGYSGKPLSVGRVQSPTLTLVVNRDREIANFVPKSHYALAVQLTTTSGETFVAGLAVP  240

Query  237  EGSTDAAGRCLQQPVAQQAADCIRAARDAQVVSVDTERVREAPPLPFDLGTLQEVCSKQL  296
            E   D +G CL+  V QQA   I+ +  A+VV+V+T R + +PPL + L+ LQ  C++ +
Sbjct  241  EQYLDESGLCLDSRVIQQAEAQIKQTGLAKVVTVETKREKKSPPLLYALSDLQGECNRLF  300

Query  297  GLDVQETLDIAQALYETHKATTYPRSDSGYLPESMLAKVPAVLDALLATDPSLRPLIGQL  356
            G++ Q+ LDIAQ+LYE HK TTYPR+D GYLPES ++ VP V+ +L+A+D++L+ L+ +L
Sbjct  301  GFGAQQVLDIAQSLYEEHKITTYPRTDCGYLPESQFSDVPNVIRSLVASDSGLQTLLPKL  360

Query  357  DRNQRSRAWNDGKVTAHHGIIPTLEPANLSAMNEKELAVYRLIRAHYLAQFLPHHEFDRT  416
            +  Q+SRAW+D K+TAHHGIIPT+  A+LS ++E E+ VY LIR +YLAQFLPH E D+T
Sbjct  361  NLRQKSRAWDDKKITAHHGIIPTIKKADLSKLSEEEMKVYDLIRRRYLAQFLPHLEMDKT  420

Query  417  VAQFSCGSQSLAAVGKQIAVTGWREVLATPGPDDADGEDAQRSQVLPALHAGLSCPVGKV  476
            VA +  ++++L A G+ I   GWR +L     D+  G+D ++ Q LP L     C V   
Sbjct  421  VATLQSSGHTLVARGNVIVAQGWR-ILFGKNVDEETGNDDEK-QGLPVLTKNQQCNVTHS  478

Query  477  DLKALKTLPPKPYTQGELIKAMKTVAKFVTDPRLKQKLRDTTGIGTEATRANIINGLIGR  536
            ++++L+T PP  YT+G L+ AMK  A+FVTDPRLKQ+LR+T G+GTEATRA +I+GLI++
Sbjct  479  EVRTLQTKPPAHYTEGTLLDAMKNAARFVTDPRLKQRLRETEGLGTEATRAGLIQGLIDK  538

Query  537  GYLVKKGRAVRASDAAFTLIDAVPSAIADPGTTAVWEQALDMIEAGQMALDTFIEKQSVW  596
            G+L+KK +++ AS  A +LID++P  + +PG TA+WEQAL+ I  G M+LD+F++KQ   
Sbjct  539  GFLLKKKKSLVASAEAVALIDSLPDLLKNPGLTALWEQALNQIAEGSMTLDAFMQKQEAF  598

Query  597  VGQLVQQYRGATLSLKLPPTPACPQCGAPMQQRTGKSGAFWSCSRYPDCK  646
            V QL+       +SL       C++CG PM++     G+FW+C+ YPDC+
Sbjct  599  VKQLIGSCMQQGMSLGNIEIRKCSECGKPMRKINHAKGTFWGCTGYPDCQ  648

> NC_016808_R1|63|G56|378773985|YP_005176228.1|Pasteurella_multocida_36950|-|54272..56323|topB1|Pmu_03290|DNA 
topoisomerase 
III
Length=683

 Score =  586 bits (2212),  Expect = 2e-168, Method: Compositional matrix adjust.
 Identities = 331/652 (51%), Positives = 478/652 (74%), Gaps = 8/652 (1%)

Query  1    MRLFLCEKPSQGKDIGRILGATQRGEGCLNGS--GVTVTWCIGHLVEAAAPEVYDAALKR  58
            M+LF+CEKPSQ++D++ +LGAT +GEG L  +  ++ VTW +GHLVE   PE YD A KR
Sbjct  1    MKLFICEKPSQARDLAGVLGATSKGEGLLATADKSIIVTWGFGHLVEQYQPEDYDEAWKR  60

Query  59   WSLEQLPIIPQQWRVEVKPKTATQFKVVKALLAKATHLVIATDADREGELIAREIIDLCG  118
            W++E LPIIP QW++  K  +  Q+ VV +L+ KAT +VIATDADREGE+IARE++DL G
Sbjct  61   WAFETLPIIPAQWKMTPKKESKKQYSVVIGLIKKATSVVIATDADREGEMIARELLDLAG  120

Query  119  YRGPIERLWLSALNDASIRTALAKLRPSAETLPMYYSALARSRADWLVGMNLSRLFTVLG  178
            YRG I+R WLSAL+DASIR AL  L+++ ET ++YY++++RSR+DWL+GMN+SRLFT+++
Sbjct  121  YRGQIQRCWLSALDDASIRKALQTLKSGKETEALYYAGMGRSRSDWLIGMNFSRLFTLMA  180

Query  179  RQAGYDG-VLSVGRVQTPTLKLVVDRDREIAAFVSVPYWAIDVSLSA-GGQTFTAQWVAP  236
            +  GY G  LSVGRVQ+PTL LVV+RDREIA FV+ +  A+ V L++ +G+TF A    P
Sbjct  181  QAKGYSGKPLSVGRVQSPTLTLVVNRDREIANFVPKSHYALAVQLTTTSGETFVAGLAVP  240

Query  237  DASADDAGRCLqqpiaqqaaqqiraagsaqVVSVETERVREGPPLLFDLGTLQEVCSKQL  296
            +   D++G CL+  + QQA  QI+ +G A+VV+VET R + +PPLL+ L+ LQ  C++ +
Sbjct  241  EQYLDESGLCLDSRVIQQAEAQIKQTGLAKVVTVETKREKKSPPLLYALSDLQGECNRLF  300

Query  297  GLDVQETLEIAQALYETHKATTYPRSDSGYLPESMFAEVPTVLDSLLKTDPTLAPIMGQL  356
            G++ Q+ L+IAQ+LYE HK TTYPR+D GYLPES F++VP V+ SL+ +D+ L  ++ +L
Sbjct  301  GFGAQQVLDIAQSLYEEHKITTYPRTDCGYLPESQFSDVPNVIRSLVASDSGLQTLLPKL  360

Query  357  DRTQRSRAWNDSKVTAHHGIIPTLEPANLSAMSEKEQAVYRLIRAHYLAQFLPHHEFDRT  416
            +  Q+SRAW+D K+TAHHGIIPT+  A+LS +SE E  VY LIR +YLAQFLPH E D+T
Sbjct  361  NLRQKSRAWDDKKITAHHGIIPTIKKADLSKLSEEEMKVYDLIRRRYLAQFLPHLEMDKT  420

Query  417  VADLSCGQQKLVATGKQVVVKGWRLVLAEPEREGSADEDGDAPRSQVLPALRDGMACQVA  476
            VA L  + + LVA G+ +V +GWR++++    E ++++D      Q LP L     C+V+
Sbjct  421  VATLQSSGHTLVARGNVIVAQGWRILFGKNVDEETGNDDE----KQGLPVLTKNQQCNVT  476

Query  477  GADIKALKTMPPKPYTQGELVKAMKGVARFVTDPRLKQKLKDTTGIGTEATRANIISGLI  536
             +++++L+T PP  YT+G L+ AMK  ARFVTDPRLKQ+L++T G+GTEATRA +I GLI
Sbjct  477  HSEVRTLQTKPPAHYTEGTLLDAMKNAARFVTDPRLKQRLRETEGLGTEATRAGLIQGLI  536

Query  537  ARGYIVKKGRSIRASDAALTLIDAVPAAIADPGTTAVWEQALDMIEAGQLTLDVFIGKQA  596
             +G+++KK +S+ AS  A++LID++P  + +PG TA+WEQAL+ I  G +TLD F+ KQ 
Sbjct  537  DKGFLLKKKKSLVASAEAVALIDSLPDLLKNPGLTALWEQALNQIAEGSMTLDAFMQKQE  596

Query  597  AWISQLIAQYGSTSLSIKVPQGPACPQCGAPTRQRTGKSGPFWSCSRYPACK  648
            A + QLI+     ++S+   +   C++CG P R+     G FW+C+ YP C+
Sbjct  597  AFVKQLIGSCMQQGMSLGNIEIRKCSECGKPMRKINHAKGTFWGCTGYPDCQ  648

> NC_016808_R1|63|G56|378773985|YP_005176228.1|Pasteurella_multocida_36950|-|54272..56323|topB1|Pmu_03290|DNA 
topoisomerase 
III
Length=683

 Score =  586 bits (2212),  Expect = 2e-168, Method: Compositional matrix adjust.
 Identities = 335/674 (50%), Positives = 493/674 (74%), Gaps = 10/674 (1%)

Query  1    MRLFLCEKPSQGKDIGRILGATQRGEGCLNGS--GVTVTWCIGHLVEAAAPEAYDEQLKR  58
            M+LF+CEKPSQ++D++ +LGAT +GEG L  +  ++ VTW +GHLVE   PE YDE  KR
Sbjct  1    MKLFICEKPSQARDLAGVLGATSKGEGLLATADKSIIVTWGFGHLVEQYQPEDYDEAWKR  60

Query  59   WSIEQLPIIPQRWQVEVKPKTATQFKVVKALLAKATQLVIATDADREGELIAREIIDLCG  118
            W++E LPIIP +W++  K  +  Q+ VV +L+ KAT +VIATDADREGE+IARE++DL G
Sbjct  61   WAFETLPIIPAQWKMTPKKESKKQYSVVIGLIKKATSVVIATDADREGEMIARELLDLAG  120

Query  119  YRGPIERLWLSALNDASIRAALGKLRPSAETLPMYYSALARSRADWLVGMNLSRLFTVLG  178
            YRG I+R WLSAL+DASIR AL  L+++ ET ++YY++++RSR+DWL+GMN+SRLFT+++
Sbjct  121  YRGQIQRCWLSALDDASIRKALQTLKSGKETEALYYAGMGRSRSDWLIGMNFSRLFTLMA  180

Query  179  RQAGYDG-VLSVGRVQTPTLKLVVDRDREIAAFVSVPYWAIDVYLTT-SGQAFTAQWVSP  236
            +  GY G  LSVGRVQ+PTL LVV+RDREIA FV+ +  A+ V LTT SG++F A    P
Sbjct  181  QAKGYSGKPLSVGRVQSPTLTLVVNRDREIANFVPKSHYALAVQLTTTSGETFVAGLAVP  240

Query  237  DTCTDDSGRCLqqpvaqqaaqqIRATGSAQVVSVETERVREGPPLPFDLGTLQELCSKQL  296
            +   D+SG CL+  V QQA  QI+ TG A+VV+VET R + +PPL + L+ LQ  C++ +
Sbjct  241  EQYLDESGLCLDSRVIQQAEAQIKQTGLAKVVTVETKREKKSPPLLYALSDLQGECNRLF  300

Query  297  GLDVQETLDIAQALYETHKATTYPRSDSGYLPESMFAEVPIVLDSLLKTDFSLRPIIDQL  356
            G++ Q+ LDIAQ+LYE HK TTYPR+D GYLPES F++VP V+ SL+ +D +L+ ++ +L
Sbjct  301  GFGAQQVLDIAQSLYEEHKITTYPRTDCGYLPESQFSDVPNVIRSLVASDSGLQTLLPKL  360

Query  357  DRTQRSRAWNDAKVSAHHGIIPTLEPANLSAMSEKELAVYKLIRAHYLAQFLPHHEFDRT  416
            +  Q+SRAW+D K++AHHGIIPT+  A+LS +SE E+ VY LIR +YLAQFLPH E D+T
Sbjct  361  NLRQKSRAWDDKKITAHHGIIPTIKKADLSKLSEEEMKVYDLIRRRYLAQFLPHLEMDKT  420

Query  417  VANLSCGQQTLTATGKQVVVKGWRLVLAEPQPEEDSDTAARSQVLPALREGVSCQVADVD  476
            VA L  + +TL A G+ +V +GWR++++  + +E+++     Q LP L     C+V++ +
Sbjct  421  VATLQSSGHTLVARGNVIVAQGWRILFGK-NVDEETGNDDEKQGLPVLTKNQQCNVTHSE  479

Query  477  LKALKTQPSRPYTQGELVKSMKGVAKLVSDPRLKQKLKDTVGIGTEATRANIISGLIARG  536
            +++L+T+P+  YT+G L+ +MK  A++V+DPRLKQ+L++T G+GTEATRA +I GLI +G
Sbjct  480  VRTLQTKPPAHYTEGTLLDAMKNAARFVTDPRLKQRLRETEGLGTEATRAGLIQGLIDKG  539

Query  537  YLMKKGRAIRASDAAFTLIDAVPAAIADPGTTAVWEQALDMIEAGQLTLDVFIGKQAAWI  596
            +L+KK +++ AS  A +LID++P  + +PG TA+WEQAL+ I  G +TLD F+ KQ A +
Sbjct  540  FLLKKKKSLVASAEAVALIDSLPDLLKNPGLTALWEQALNQIAEGSMTLDAFMQKQEAFV  599

Query  597  SQLITQYASASLSIKVPHGPACPQCGAPTRQRSGKSGPFWSCSRYPDCKGTLPVESGTSK  656
             QLI      ++S+   +   C++CG P R+ +   G FW+C+ YPDC+     +  + K
Sbjct  600  KQLIGSCMQQGMSLGNIEIRKCSECGKPMRKINHAKGTFWGCTGYPDCQ-----HKEADK  654

Query  657  RVASRSRRGGRKDS  670
            +V S S ++++K S
Sbjct  655  KVKSASNKSAKKSS  668

> NC_016808_R1|63|G56|378773985|YP_005176228.1|Pasteurella_multocida_36950|-|54272..56323|topB1|Pmu_03290|DNA 
topoisomerase 
III
Length=683

 Score =  585 bits (2209),  Expect = 4e-168, Method: Compositional matrix adjust.
 Identities = 335/674 (50%), Positives = 492/674 (73%), Gaps = 10/674 (1%)

Query  1    MRLFLCEKPSQGKDIGRILGATQRGEGCLNGS--GVTVTWCIGHLVEAAAPEAYDEQLKR  58
            M+LF+CEKPSQ++D++ +LGAT +GEG L  +  ++ VTW +GHLVE   PE YDE  KR
Sbjct  1    MKLFICEKPSQARDLAGVLGATSKGEGLLATADKSIIVTWGFGHLVEQYQPEDYDEAWKR  60

Query  59   WSIEQLPIIPQRWQVEVKPKTATQFKVVKALLAKATQLVIATDADREGELIAREIIDLCG  118
            W++E LPIIP +W++  K  +  Q+ VV +L+ KAT +VIATDADREGE+IARE++DL G
Sbjct  61   WAFETLPIIPAQWKMTPKKESKKQYSVVIGLIKKATSVVIATDADREGEMIARELLDLAG  120

Query  119  YRGPIERLWLSALNDASIRAALGKLRPSAETLPMYYSALARSRADWLVGMNLSRLFTVLG  178
            YRG I+R WLSAL+DASIR AL  L+++ ET ++YY++++RSR+DWL+GMN+SRLFT+++
Sbjct  121  YRGQIQRCWLSALDDASIRKALQTLKSGKETEALYYAGMGRSRSDWLIGMNFSRLFTLMA  180

Query  179  RQAGYDG-VLSVGRVQTPTLKLVVDRDREIAAFVSVPYWAIDVYLTT-SGQAFTAQWVSP  236
            +  GY G  LSVGRVQ+PTL LVV+RDREIA FV+ +  A+ V LTT SG++F A    P
Sbjct  181  QAKGYSGKPLSVGRVQSPTLTLVVNRDREIANFVPKSHYALAVQLTTTSGETFVAGLAVP  240

Query  237  DTCTDDSGRCLqqpvaqqaaqqIRATGSAQVVSVETERVREGPPLPFDLGTLQELCSKQL  296
            +   D+SG CL+  V QQA  QI+ TG A+VV+VET R + +PPL + L+ LQ  C++ +
Sbjct  241  EQYLDESGLCLDSRVIQQAEAQIKQTGLAKVVTVETKREKKSPPLLYALSDLQGECNRLF  300

Query  297  GLDVQETLDIAQALYETHKATTYPRSDSGYLPESMFAEVPIVLDSLPKTDFSLRPIIDQL  356
            G++ Q+ LDIAQ+LYE HK TTYPR+D GYLPES F++VP V+ SL  +D +L+ ++ +L
Sbjct  301  GFGAQQVLDIAQSLYEEHKITTYPRTDCGYLPESQFSDVPNVIRSLVASDSGLQTLLPKL  360

Query  357  DRTQRSRAWNDAKVSAHHGIIPTLEPANLSAMSEKELAVYKLIRAHYLAQFLPHHEFDRT  416
            +  Q+SRAW+D K++AHHGIIPT+  A+LS +SE E+ VY LIR +YLAQFLPH E D+T
Sbjct  361  NLRQKSRAWDDKKITAHHGIIPTIKKADLSKLSEEEMKVYDLIRRRYLAQFLPHLEMDKT  420

Query  417  VANLSCGQQTLTATGKQVVVKGWRLVLAEPQPEEDSDTAARSQVLPALREGVSCQVADVD  476
            VA L  + +TL A G+ +V +GWR++++  + +E+++     Q LP L     C+V++ +
Sbjct  421  VATLQSSGHTLVARGNVIVAQGWRILFGK-NVDEETGNDDEKQGLPVLTKNQQCNVTHSE  479

Query  477  LKALKTQPSRPYTQGELVKSMKGVAKLVSDPRLKQKLKDTVGIGTEATRANIISGLIARG  536
            +++L+T+P+  YT+G L+ +MK  A++V+DPRLKQ+L++T G+GTEATRA +I GLI +G
Sbjct  480  VRTLQTKPPAHYTEGTLLDAMKNAARFVTDPRLKQRLRETEGLGTEATRAGLIQGLIDKG  539

Query  537  YLMKKGRAIRASDAAFTLIDAVPAAIADPGTTAVWEQALDMIEAGQLTLDVFIGKQAAWI  596
            +L+KK +++ AS  A +LID++P  + +PG TA+WEQAL+ I  G +TLD F+ KQ A +
Sbjct  540  FLLKKKKSLVASAEAVALIDSLPDLLKNPGLTALWEQALNQIAEGSMTLDAFMQKQEAFV  599

Query  597  SQLITQYASASLSIKVPHGPACPQCGAPTRQRSGKSGPFWSCSRYPDCKGTLPVESGTSK  656
             QLI      ++S+   +   C++CG P R+ +   G FW+C+ YPDC+     +  + K
Sbjct  600  KQLIGSCMQQGMSLGNIEIRKCSECGKPMRKINHAKGTFWGCTGYPDCQ-----HKEADK  654

Query  657  RVASRSRRGGRKDS  670
            +V S S ++++K S
Sbjct  655  KVKSASNKSAKKSS  668

> NC_016808_R1|63|G56|378773985|YP_005176228.1|Pasteurella_multocida_36950|-|54272..56323|topB1|Pmu_03290|DNA 
topoisomerase 
III
Length=683

 Score =  584 bits (2204),  Expect = 1e-167, Method: Compositional matrix adjust.
 Identities = 329/649 (51%), Positives = 480/649 (74%), Gaps = 5/649 (0%)

Query  1    MRLFLCEKPSQGKDIGRILGATQRGEGCLSGS--GVTITWCIGHLVEAAAPEVYDAALKR  58
            M+LF+CEKPSQ++D++ +LGAT +GEG L+ +  ++ +TW +GHLVE   PE YD A KR
Sbjct  1    MKLFICEKPSQARDLAGVLGATSKGEGLLATADKSIIVTWGFGHLVEQYQPEDYDEAWKR  60

Query  59   WSLEQLPIIPQQWRVEVKPKTATQFKVVKALLAKATHLVIATDADREGELIAREIIDLCG  118
            W++E LPIIP QW++  K  +  Q+ VV +L+ KAT +VIATDADREGE+IARE++DL G
Sbjct  61   WAFETLPIIPAQWKMTPKKESKKQYSVVIGLIKKATSVVIATDADREGEMIARELLDLAG  120

Query  119  YRGPIERLWLSALNDASIRTALGKLRPSSDTLPMYYSALARSRADWLVGMNLSRLFTLLG  178
            YRG I+R WLSAL+DASIR AL  L+++ +T ++YY++++RSR+DWL+GMN+SRLFTL++
Sbjct  121  YRGQIQRCWLSALDDASIRKALQTLKSGKETEALYYAGMGRSRSDWLIGMNFSRLFTLMA  180

Query  179  RQAGYDG-VLSVGRVQTPTLKLVVDRDREIAAFKSAPFWAIDVSLST-EGQAFSAQWVAP  236
            +  GY G  LSVGRVQ+PTL LVV+RDREIA F + +  A+ V L+T  G++F A    P
Sbjct  181  QAKGYSGKPLSVGRVQSPTLTLVVNRDREIANFVPKSHYALAVQLTTTSGETFVAGLAVP  240

Query  237  DGCTDDAGRClqqpvaqqaalqIRVADNTQVVSVETERVREGPPLLFDLSTLQEVCSKQL  296
            +   D++G CL+  V QQA  QI+ ++ ++VV+VET R + +PPLL+ LS LQ  C++ +
Sbjct  241  EQYLDESGLCLDSRVIQQAEAQIKQTGLAKVVTVETKREKKSPPLLYALSDLQGECNRLF  300

Query  297  GLDVQETLQIAQALYETHKATTYPRSDSGYLPESMFAEVPAVLDSLLKTDPSLRPIMSQL  356
            G++ Q+ L+IAQ+LYE HK TTYPR+D GYLPES F++VP V+ SL+ +D++L+ ++++L
Sbjct  301  GFGAQQVLDIAQSLYEEHKITTYPRTDCGYLPESQFSDVPNVIRSLVASDSGLQTLLPKL  360

Query  357  DRSQRSRAWNDGKVTAHHGIIPTLEPANLSPLSEKELAVYRLIRAHYLAQFLPHHEFDRT  416
            +  Q+SRAW+D K+TAHHGIIPT+  A+LS LSE E+ VY LIR +YLAQFLPH E D+T
Sbjct  361  NLRQKSRAWDDKKITAHHGIIPTIKKADLSKLSEEEMKVYDLIRRRYLAQFLPHLEMDKT  420

Query  417  VAEFSCGQQMLVATGKQVVVKGWRLVLAEPQADEDGDDAARSQVLPPLRGGLACQVAEVE  476
            VA +  + + LVA G+ +V +GWR++++    +E G+D  + Q LP L     C+V++ E
Sbjct  421  VATLQSSGHTLVARGNVIVAQGWRILFGKNVDEETGNDDEK-QGLPVLTKNQQCNVTHSE  479

Query  477  IKALKTMPPKPYTQGELVKSMKGIARFVTDPRLKQKLKDTTGIGTEATRANIISVLIARG  536
            +++L+T PP  YT+G L+ +MK  ARFVTDPRLKQ+L++T G+GTEATRA +I  LI +G
Sbjct  480  VRTLQTKPPAHYTEGTLLDAMKNAARFVTDPRLKQRLRETEGLGTEATRAGLIQGLIDKG  539

Query  537  YIVKKGRSIRASDAAFTLIDAVPAAIADPGTTAVWEQALDMIEAGQLTLDVFLSKQAAWI  596
            +++KK +S+ AS  A +LID++P  + +PG TA+WEQAL+ I  G +TLD F+ KQ A +
Sbjct  540  FLLKKKKSLVASAEAVALIDSLPDLLKNPGLTALWEQALNQIAEGSMTLDAFMQKQEAFV  599

Query  597  SQLIAQYGSMSLSIKLPHGPACPQCGAATRQRTGKSGPFWSCSRYPDCK  645
             QLI+     ++S+   +   C++CG + R+     G FW+C+ YPDC+
Sbjct  600  KQLIGSCMQQGMSLGNIEIRKCSECGKPMRKINHAKGTFWGCTGYPDCQ  648

> NC_016808_R1|63|G56|378773985|YP_005176228.1|Pasteurella_multocida_36950|-|54272..56323|topB1|Pmu_03290|DNA 
topoisomerase 
III
Length=683

 Score =  584 bits (2204),  Expect = 1e-167, Method: Compositional matrix adjust.
 Identities = 329/649 (51%), Positives = 480/649 (74%), Gaps = 5/649 (0%)

Query  1    MRLFLCEKPSQGKDIGRILGATQRGEGCLSGS--GVTITWCIGHLVEAAAPEVYDAALKR  58
            M+LF+CEKPSQ++D++ +LGAT +GEG L+ +  ++ +TW +GHLVE   PE YD A KR
Sbjct  1    MKLFICEKPSQARDLAGVLGATSKGEGLLATADKSIIVTWGFGHLVEQYQPEDYDEAWKR  60

Query  59   WSLEQLPIIPQQWRVEVKPKTATQFKVVKALLAKATHLVIATDADREGELIAREIIDLCG  118
            W++E LPIIP QW++  K  +  Q+ VV +L+ KAT +VIATDADREGE+IARE++DL G
Sbjct  61   WAFETLPIIPAQWKMTPKKESKKQYSVVIGLIKKATSVVIATDADREGEMIARELLDLAG  120

Query  119  YRGPIERLWLSALNDASIRTALGKLRPSSDTLPMYYSALARSRADWLVGMNLSRLFTLLG  178
            YRG I+R WLSAL+DASIR AL  L+++ +T ++YY++++RSR+DWL+GMN+SRLFTL++
Sbjct  121  YRGQIQRCWLSALDDASIRKALQTLKSGKETEALYYAGMGRSRSDWLIGMNFSRLFTLMA  180

Query  179  RQAGYDG-VLSVGRVQTPTLKLVVDRDREIAAFKSAPFWAIDVSLST-EGQAFSAQWVAP  236
            +  GY G  LSVGRVQ+PTL LVV+RDREIA F + +  A+ V L+T  G++F A    P
Sbjct  181  QAKGYSGKPLSVGRVQSPTLTLVVNRDREIANFVPKSHYALAVQLTTTSGETFVAGLAVP  240

Query  237  DGCTDDAGRClqqpvaqqaalqIRVADNTQVVSVETERVREGPPLLFDLSTLQEVCSKQL  296
            +   D++G CL+  V QQA  QI+ ++ ++VV+VET R + +PPLL+ LS LQ  C++ +
Sbjct  241  EQYLDESGLCLDSRVIQQAEAQIKQTGLAKVVTVETKREKKSPPLLYALSDLQGECNRLF  300

Query  297  GLDVQETLQIAQALYETHKATTYPRSDSGYLPESMFAEVPAVLDSLLKTDPSLRPIMSQL  356
            G++ Q+ L+IAQ+LYE HK TTYPR+D GYLPES F++VP V+ SL+ +D++L+ ++++L
Sbjct  301  GFGAQQVLDIAQSLYEEHKITTYPRTDCGYLPESQFSDVPNVIRSLVASDSGLQTLLPKL  360

Query  357  DRSQRSRAWNDGKVTAHHGIIPTLEPANLSPLSEKELAVYRLIRAHYLAQFLPHHEFDRT  416
            +  Q+SRAW+D K+TAHHGIIPT+  A+LS LSE E+ VY LIR +YLAQFLPH E D+T
Sbjct  361  NLRQKSRAWDDKKITAHHGIIPTIKKADLSKLSEEEMKVYDLIRRRYLAQFLPHLEMDKT  420

Query  417  VAEFSCGQQMLVATGKQVVVKGWRLVLAEPQADEDGDDAARSQVLPPLRGGLACQVAEVE  476
            VA +  + + LVA G+ +V +GWR++++    +E G+D  + Q LP L     C+V++ E
Sbjct  421  VATLQSSGHTLVARGNVIVAQGWRILFGKNVDEETGNDDEK-QGLPVLTKNQQCNVTHSE  479

Query  477  IKALKTMPPKPYTQGELVKSMKGIARFVTDPRLKQKLKDTTGIGTEATRANIISVLIARG  536
            +++L+T PP  YT+G L+ +MK  ARFVTDPRLKQ+L++T G+GTEATRA +I  LI +G
Sbjct  480  VRTLQTKPPAHYTEGTLLDAMKNAARFVTDPRLKQRLRETEGLGTEATRAGLIQGLIDKG  539

Query  537  YIVKKGRSIRASDAAFTLIDAVPAAIADPGTTAVWEQALDMIEAGQLTLDVFLSKQAAWI  596
            +++KK +S+ AS  A +LID++P  + +PG TA+WEQAL+ I  G +TLD F+ KQ A +
Sbjct  540  FLLKKKKSLVASAEAVALIDSLPDLLKNPGLTALWEQALNQIAEGSMTLDAFMQKQEAFV  599

Query  597  SQLIAQYGSMSLSIKLPHGPACPQCGAATRQRTGKSGPFWSCSRYPDCK  645
             QLI+     ++S+   +   C++CG + R+     G FW+C+ YPDC+
Sbjct  600  KQLIGSCMQQGMSLGNIEIRKCSECGKPMRKINHAKGTFWGCTGYPDCQ  648

> NC_016808_R1|63|G56|378773985|YP_005176228.1|Pasteurella_multocida_36950|-|54272..56323|topB1|Pmu_03290|DNA 
topoisomerase 
III
Length=683

 Score =  584 bits (2204),  Expect = 1e-167, Method: Compositional matrix adjust.
 Identities = 329/649 (51%), Positives = 480/649 (74%), Gaps = 5/649 (0%)

Query  1    MRLFLCEKPSQGKDIGRILGATQRGEGCLSGS--GVTITWCIGHLVEAAAPEVYDAALKR  58
            M+LF+CEKPSQ++D++ +LGAT +GEG L+ +  ++ +TW +GHLVE   PE YD A KR
Sbjct  1    MKLFICEKPSQARDLAGVLGATSKGEGLLATADKSIIVTWGFGHLVEQYQPEDYDEAWKR  60

Query  59   WSLEQLPIIPQQWRVEVKPKTATQFKVVKALLAKATHLVIATDADREGELIAREIIDLCG  118
            W++E LPIIP QW++  K  +  Q+ VV +L+ KAT +VIATDADREGE+IARE++DL G
Sbjct  61   WAFETLPIIPAQWKMTPKKESKKQYSVVIGLIKKATSVVIATDADREGEMIARELLDLAG  120

Query  119  YRGPIERLWLSALNDASIRTALGKLRPSSDTLPMYYSALARSRADWLVGMNLSRLFTLLG  178
            YRG I+R WLSAL+DASIR AL  L+++ +T ++YY++++RSR+DWL+GMN+SRLFTL++
Sbjct  121  YRGQIQRCWLSALDDASIRKALQTLKSGKETEALYYAGMGRSRSDWLIGMNFSRLFTLMA  180

Query  179  RQAGYDG-VLSVGRVQTPTLKLVVDRDREIAAFKSAPFWAIDVSLST-EGQAFSAQWVAP  236
            +  GY G  LSVGRVQ+PTL LVV+RDREIA F + +  A+ V L+T  G++F A    P
Sbjct  181  QAKGYSGKPLSVGRVQSPTLTLVVNRDREIANFVPKSHYALAVQLTTTSGETFVAGLAVP  240

Query  237  DGCTDDAGRClqqpvaqqaalqIRVADNTQVVSVETERVREGPPLLFDLSTLQEVCSKQL  296
            +   D++G CL+  V QQA  QI+ ++ ++VV+VET R + +PPLL+ LS LQ  C++ +
Sbjct  241  EQYLDESGLCLDSRVIQQAEAQIKQTGLAKVVTVETKREKKSPPLLYALSDLQGECNRLF  300

Query  297  GLDVQETLQIAQALYETHKATTYPRSDSGYLPESMFAEVPAVLDSLLKTDPSLRPIMSQL  356
            G++ Q+ L+IAQ+LYE HK TTYPR+D GYLPES F++VP V+ SL+ +D++L+ ++++L
Sbjct  301  GFGAQQVLDIAQSLYEEHKITTYPRTDCGYLPESQFSDVPNVIRSLVASDSGLQTLLPKL  360

Query  357  DRSQRSRAWNDGKVTAHHGIIPTLEPANLSPLSEKELAVYRLIRAHYLAQFLPHHEFDRT  416
            +  Q+SRAW+D K+TAHHGIIPT+  A+LS LSE E+ VY LIR +YLAQFLPH E D+T
Sbjct  361  NLRQKSRAWDDKKITAHHGIIPTIKKADLSKLSEEEMKVYDLIRRRYLAQFLPHLEMDKT  420

Query  417  VAEFSCGQQMLVATGKQVVVKGWRLVLAEPQADEDGDDAARSQVLPPLRGGLACQVAEVE  476
            VA +  + + LVA G+ +V +GWR++++    +E G+D  + Q LP L     C+V++ E
Sbjct  421  VATLQSSGHTLVARGNVIVAQGWRILFGKNVDEETGNDDEK-QGLPVLTKNQQCNVTHSE  479

Query  477  IKALKTMPPKPYTQGELVKSMKGIARFVTDPRLKQKLKDTTGIGTEATRANIISVLIARG  536
            +++L+T PP  YT+G L+ +MK  ARFVTDPRLKQ+L++T G+GTEATRA +I  LI +G
Sbjct  480  VRTLQTKPPAHYTEGTLLDAMKNAARFVTDPRLKQRLRETEGLGTEATRAGLIQGLIDKG  539

Query  537  YIVKKGRSIRASDAAFTLIDAVPAAIADPGTTAVWEQALDMIEAGQLTLDVFLSKQAAWI  596
            +++KK +S+ AS  A +LID++P  + +PG TA+WEQAL+ I  G +TLD F+ KQ A +
Sbjct  540  FLLKKKKSLVASAEAVALIDSLPDLLKNPGLTALWEQALNQIAEGSMTLDAFMQKQEAFV  599

Query  597  SQLIAQYGSMSLSIKLPHGPACPQCGAATRQRTGKSGPFWSCSRYPDCK  645
             QLI+     ++S+   +   C++CG + R+     G FW+C+ YPDC+
Sbjct  600  KQLIGSCMQQGMSLGNIEIRKCSECGKPMRKINHAKGTFWGCTGYPDCQ  648

> NC_016808_R1|63|G56|378773985|YP_005176228.1|Pasteurella_multocida_36950|-|54272..56323|topB1|Pmu_03290|DNA 
topoisomerase 
III
Length=683

 Score =  584 bits (2205),  Expect = 7e-168, Method: Compositional matrix adjust.
 Identities = 333/674 (50%), Positives = 493/674 (74%), Gaps = 10/674 (1%)

Query  1    MRLFLCEKPSQGKDIGRILGATQRGEGCLNGS--GVTVTWCIGHLVEAAAPEAYDEQLKR  58
            M+LF+CEKPSQ++D++ +LGAT +GEG L  +  ++ VTW +GHLVE   PE YDE  KR
Sbjct  1    MKLFICEKPSQARDLAGVLGATSKGEGLLATADKSIIVTWGFGHLVEQYQPEDYDEAWKR  60

Query  59   WSIEQLPIIPQRWQVEVKPKTATQFKVVKALLAKATQLVIATDADREGELIAREIIDLCG  118
            W++E LPIIP +W++  K  +  Q+ VV +L+ KAT +VIATDADREGE+IARE++DL G
Sbjct  61   WAFETLPIIPAQWKMTPKKESKKQYSVVIGLIKKATSVVIATDADREGEMIARELLDLAG  120

Query  119  YRGPIERLWLSALNDASIRAALGKLRPSAETLPMYYSALARSRADWLVGMNLSRLFTVLG  178
            YRG I+R WLSAL+DASIR AL  L+++ ET ++YY++++RSR+DWL+GMN+SRLFT+++
Sbjct  121  YRGQIQRCWLSALDDASIRKALQTLKSGKETEALYYAGMGRSRSDWLIGMNFSRLFTLMA  180

Query  179  RQAGYDG-VLSVGRVQTPTLKLVVDRDREIAAFVSVPYWAIDVYLTT-SGQAFTAQWVSP  236
            +  GY G  LSVGRVQ+PTL LVV+RDREIA FV+ +  A+ V LTT SG++F A    P
Sbjct  181  QAKGYSGKPLSVGRVQSPTLTLVVNRDREIANFVPKSHYALAVQLTTTSGETFVAGLAVP  240

Query  237  DTCTDDSGRCLqqpvaqqaaqqLRATGSAQVVSVETERVREGPPLPFDLGTLQELCSKQL  296
            +   D+SG CL+  V QQA  Q++ TG A+VV+VET R + +PPL + L+ LQ  C++ +
Sbjct  241  EQYLDESGLCLDSRVIQQAEAQIKQTGLAKVVTVETKREKKSPPLLYALSDLQGECNRLF  300

Query  297  GLDVQETLDIAQALYETHKATTYPRSDSGYLPESMFAEVPIVLDSLLKTDFSLRPIIDQL  356
            G++ Q+ LDIAQ+LYE HK TTYPR+D GYLPES F++VP V+ SL+ +D +L+ ++ +L
Sbjct  301  GFGAQQVLDIAQSLYEEHKITTYPRTDCGYLPESQFSDVPNVIRSLVASDSGLQTLLPKL  360

Query  357  DRTQRSRAWNDAKVSAHHGIIPTLEPANLSAMSEKELAVYKLIRAHYLAQFLPHHEFDRT  416
            +  Q+SRAW+D K++AHHGIIPT+  A+LS +SE E+ VY LIR +YLAQFLPH E D+T
Sbjct  361  NLRQKSRAWDDKKITAHHGIIPTIKKADLSKLSEEEMKVYDLIRRRYLAQFLPHLEMDKT  420

Query  417  VANLSCGQQTLTATGKQVVVKGWRLVLAEPQPEEDSDTAARSQVLPALREGVSCQVADAD  476
            VA L  + +TL A G+ +V +GWR++++  + +E+++     Q LP L     C+V++++
Sbjct  421  VATLQSSGHTLVARGNVIVAQGWRILFGK-NVDEETGNDDEKQGLPVLTKNQQCNVTHSE  479

Query  477  LKALKTQPSRPYTQGELVKSMKGVAKLISDPRLKQKLKDTVGIGTEATRANIISGLIARG  536
            +++L+T+P+  YT+G L+ +MK  A++++DPRLKQ+L++T G+GTEATRA +I GLI +G
Sbjct  480  VRTLQTKPPAHYTEGTLLDAMKNAARFVTDPRLKQRLRETEGLGTEATRAGLIQGLIDKG  539

Query  537  YLMKKGRAIRASDAAFTLIDAVPAAIADPGTTAVWEQALDMIEAGQLTLDVFIGKQAAWI  596
            +L+KK +++ AS  A +LID++P  + +PG TA+WEQAL+ I  G +TLD F+ KQ A +
Sbjct  540  FLLKKKKSLVASAEAVALIDSLPDLLKNPGLTALWEQALNQIAEGSMTLDAFMQKQEAFV  599

Query  597  SQLITQYASASLSIKVPHGPACPQCGAPTRQRSGKSGPFWSCSRYPDCKGTLPVESGTSK  656
             QLI      ++S+   +   C++CG P R+ +   G FW+C+ YPDC+     +  + K
Sbjct  600  KQLIGSCMQQGMSLGNIEIRKCSECGKPMRKINHAKGTFWGCTGYPDCQ-----HKEADK  654

Query  657  RVASRSRRGCRKDS  670
            +V S S ++ +K S
Sbjct  655  KVKSASNKSAKKSS  668

> NC_016808_R1|63|G56|378773985|YP_005176228.1|Pasteurella_multocida_36950|-|54272..56323|topB1|Pmu_03290|DNA 
topoisomerase 
III
Length=683

 Score =  584 bits (2204),  Expect = 9e-168, Method: Compositional matrix adjust.
 Identities = 334/674 (50%), Positives = 493/674 (74%), Gaps = 10/674 (1%)

Query  1    MRLFLCEKPSQGKDIGRILGATQRGEGCLNGS--GVTVTWCIGHLVEAAAPEAYDEQLKR  58
            M+LF+CEKPSQ++D++ +LGAT +GEG L  +  ++ VTW +GHLVE   PE YDE  KR
Sbjct  1    MKLFICEKPSQARDLAGVLGATSKGEGLLATADKSIIVTWGFGHLVEQYQPEDYDEAWKR  60

Query  59   WSIEQLPIIPQRWQVEVKPKTATQFKVVKALLAKATQLVIATDADREGELIAREIIDLCG  118
            W++E LPIIP +W++  K  +  Q+ VV +L+ KAT +VIATDADREGE+IARE++DL G
Sbjct  61   WAFETLPIIPAQWKMTPKKESKKQYSVVIGLIKKATSVVIATDADREGEMIARELLDLAG  120

Query  119  YRGPIERLWLSALNDASIRAALGKLRPSAETLPMYYSALARSRADWLVGMNLSRLFTVLG  178
            YRG I+R WLSAL+DASIR AL  L+++ ET ++YY++++RSR+DWL+GMN+SRLFT+++
Sbjct  121  YRGQIQRCWLSALDDASIRKALQTLKSGKETEALYYAGMGRSRSDWLIGMNFSRLFTLMA  180

Query  179  RQAGYDG-VLSVGRVQTPTLKLVVDRDREIAAFVSVPYWAIDVYLTT-SGQAFTAQWISP  236
            +  GY G  LSVGRVQ+PTL LVV+RDREIA FV+ +  A+ V LTT SG++F A    P
Sbjct  181  QAKGYSGKPLSVGRVQSPTLTLVVNRDREIANFVPKSHYALAVQLTTTSGETFVAGLAVP  240

Query  237  DTCTDDSGRCLqqpvaqqaaqqIRATGSAQVVSVETERVREGPPLPFDLGTLQELCSKQL  296
            +   D+SG CL+  V QQA  QI+ TG A+VV+VET R + +PPL + L+ LQ  C++ +
Sbjct  241  EQYLDESGLCLDSRVIQQAEAQIKQTGLAKVVTVETKREKKSPPLLYALSDLQGECNRLF  300

Query  297  GLDVQETLDIAQALYETHKATTYPRSDSGYLPESMFAEVPIVLDSLLKTDFSLRPIIDQL  356
            G++ Q+ LDIAQ+LYE HK TTYPR+D GYLPES F++VP V+ SL+ +D +L+ ++ +L
Sbjct  301  GFGAQQVLDIAQSLYEEHKITTYPRTDCGYLPESQFSDVPNVIRSLVASDSGLQTLLPKL  360

Query  357  DRTQRSRAWNDAKVSAHHGIIPTLEPANLSAMSEKELAVYKLIRAHYLAQFLPHHEFDRT  416
            +  Q+SRAW+D K++AHHGIIPT+  A+LS +SE E+ VY LIR +YLAQFLPH E D+T
Sbjct  361  NLRQKSRAWDDKKITAHHGIIPTIKKADLSKLSEEEMKVYDLIRRRYLAQFLPHLEMDKT  420

Query  417  VANLSCGQQTLTATGKQVVVKGWRLVLAEPQPEEDSDTAARSQVLPALREGVSCQVADVD  476
            VA L  + +TL A G+ +V +GWR++++  + +E+++     Q LP L     C+V++ +
Sbjct  421  VATLQSSGHTLVARGNVIVAQGWRILFGK-NVDEETGNDDEKQGLPVLTKNQQCNVTHSE  479

Query  477  LKALKTQPSRPYTQGELVKSMKGVAKLVSDPRLKQKLKDTVGIGTEATRANIISGLIARG  536
            +++L+T+P+  YT+G L+ +MK  A++V+DPRLKQ+L++T G+GTEATRA +I GLI +G
Sbjct  480  VRTLQTKPPAHYTEGTLLDAMKNAARFVTDPRLKQRLRETEGLGTEATRAGLIQGLIDKG  539

Query  537  YLMKKGRAIRASDAAFTLIDAVPAAIADPGTTAVWEQALDMIEAGQLTLDVFIGKQAAWI  596
            +L+KK +++ AS  A +LID++P  + +PG TA+WEQAL+ I  G +TLD F+ KQ A +
Sbjct  540  FLLKKKKSLVASAEAVALIDSLPDLLKNPGLTALWEQALNQIAEGSMTLDAFMQKQEAFV  599

Query  597  SQLITQYASASLSIKVPHGPACPQCGAPTHQRSGKSGPFWSCSRYPDCKGTLPVESGTSK  656
             QLI      ++S+   +   C++CG P ++ +   G FW+C+ YPDC+     +  + K
Sbjct  600  KQLIGSCMQQGMSLGNIEIRKCSECGKPMRKINHAKGTFWGCTGYPDCQ-----HKEADK  654

Query  657  RVASRSRRGGRKDS  670
            +V S S ++++K S
Sbjct  655  KVKSASNKSAKKSS  668

> NC_016808_R1|63|G56|378773985|YP_005176228.1|Pasteurella_multocida_36950|-|54272..56323|topB1|Pmu_03290|DNA 
topoisomerase 
III
Length=683

 Score =  583 bits (2203),  Expect = 1e-167, Method: Compositional matrix adjust.
 Identities = 330/649 (51%), Positives = 479/649 (74%), Gaps = 5/649 (0%)

Query  1    MRLFLCEKPSQGKDIGRILGATQRGEGCLNGS--GVTVTWCIGHLVEAAAPEVYDAALKR  58
            M+LF+CEKPSQ++D++ +LGAT +GEG L  +  ++ VTW +GHLVE   PE YD A KR
Sbjct  1    MKLFICEKPSQARDLAGVLGATSKGEGLLATADKSIIVTWGFGHLVEQYQPEDYDEAWKR  60

Query  59   WSLEQLPIIPQQWRVEVKPQTATQFKVVKTLLAKATHLVIATDADREGELIAREIIDLCG  118
            W++E LPIIP QW++  K ++  Q+ VV  L+ KAT +VIATDADREGE+IARE++DL G
Sbjct  61   WAFETLPIIPAQWKMTPKKESKKQYSVVIGLIKKATSVVIATDADREGEMIARELLDLAG  120

Query  119  YRGPIERLWLSALNDASIRTALAKLRPSAETLPMYYSALARSRADWLVGMNLSRLFTVLG  178
            YRG I+R WLSAL+DASIR AL  L+++ ET ++YY++++RSR+DWL+GMN+SRLFT+++
Sbjct  121  YRGQIQRCWLSALDDASIRKALQTLKSGKETEALYYAGMGRSRSDWLIGMNFSRLFTLMA  180

Query  179  RQAGYDG-VLSVGRVQTPTLKLVVDRDREIAAFESVPYWAIDVSLSA-GGQTFTAQWVAP  236
            +  GY G  LSVGRVQ+PTL LVV+RDREIA F + +  A+ V L++ +G+TF A    P
Sbjct  181  QAKGYSGKPLSVGRVQSPTLTLVVNRDREIANFVPKSHYALAVQLTTTSGETFVAGLAVP  240

Query  237  DASTDDAGRCLqqpvaqqaaqqiraagsaqVVSVETERVREGPPLLFDLGTLQEVCSKQL  296
            +   D++G CL+  V QQA  QI+ +G A+VV+VET R + +PPLL+ L+ LQ  C++ +
Sbjct  241  EQYLDESGLCLDSRVIQQAEAQIKQTGLAKVVTVETKREKKSPPLLYALSDLQGECNRLF  300

Query  297  GLDVQETLEIAQALYETHKATTYPRSDSGYLPESMFAEVPTVLDSLLKTDPSLRPIMEQL  356
            G++ Q+ L+IAQ+LYE HK TTYPR+D GYLPES F++VP V+ SL+ +D++L+ ++ +L
Sbjct  301  GFGAQQVLDIAQSLYEEHKITTYPRTDCGYLPESQFSDVPNVIRSLVASDSGLQTLLPKL  360

Query  357  DRSVRSRAWNDTKVSAHHGIIPTLEPANLSAMSEKEQAVYRLIRAHYLAQFLPHHEFDRT  416
            +   +SRAW+D K++AHHGIIPT+  A+LS +SE E  VY LIR +YLAQFLPH E D+T
Sbjct  361  NLRQKSRAWDDKKITAHHGIIPTIKKADLSKLSEEEMKVYDLIRRRYLAQFLPHLEMDKT  420

Query  417  VAELFCGQQKLVATGKQVVAKGWRLVLAEPQADEDGDGAARSQVLPALRDGMACQIAGAD  476
            VA L  + + LVA G+ +VA+GWR++++    +E G++  + Q LP L     C+++ ++
Sbjct  421  VATLQSSGHTLVARGNVIVAQGWRILFGKNVDEETGNDDEK-QGLPVLTKNQQCNVTHSE  479

Query  477  IKALKTMPPKPYTQGELVKAMKGVARFVTDPRLKQKLKDTTGIGTEATRANIISGLIARG  536
            +++L+T PP  YT+G L+ AMK  ARFVTDPRLKQ+L++T G+GTEATRA +I GLI +G
Sbjct  480  VRTLQTKPPAHYTEGTLLDAMKNAARFVTDPRLKQRLRETEGLGTEATRAGLIQGLIDKG  539

Query  537  YIVKKGRSIRASDAAFTLIDAVPAAIADPGTTAVWEQALDMIEGGQLTLDVFIGKQAAWI  596
            +++KK +S+ AS  A +LID++P  + +PG TA+WEQAL+ I  G +TLD F+ KQ A +
Sbjct  540  FLLKKKKSLVASAEAVALIDSLPDLLKNPGLTALWEQALNQIAEGSMTLDAFMQKQEAFV  599

Query  597  SQLIAQYGSTSLSIKVPQGPACPQCGAPTRQRTGKSGPFWSCSRYPDCK  645
             QLI+     ++S+   +   C++CG P R+     G FW+C+ YPDC+
Sbjct  600  KQLIGSCMQQGMSLGNIEIRKCSECGKPMRKINHAKGTFWGCTGYPDCQ  648

> NC_016808_R1|63|G56|378773985|YP_005176228.1|Pasteurella_multocida_36950|-|54272..56323|topB1|Pmu_03290|DNA 
topoisomerase 
III
Length=683

 Score =  583 bits (2203),  Expect = 1e-167, Method: Compositional matrix adjust.
 Identities = 329/680 (49%), Positives = 488/680 (72%), Gaps = 16/680 (2%)

Query  1    MRLFLCEKPSQGKDIGRILGATQRGEGCLNGS--GVTVTWCIGHLVEAAPPEAYDEQLKR  58
            M+LF+CEKPSQ++D++ +LGAT +GEG L  +  ++ VTW +GHLVE   PE YDE  KR
Sbjct  1    MKLFICEKPSQARDLAGVLGATSKGEGLLATADKSIIVTWGFGHLVEQYQPEDYDEAWKR  60

Query  59   WSVEQLPIIPQHWRVEVKPKTATQFKVVKALLAKATHLVIATDADREGELIAREIVELCG  118
            W+ E LPIIP +W++  K  +  Q+ VV +L+ KAT +VIATDADREGE+IARE+++L G
Sbjct  61   WAFETLPIIPAQWKMTPKKESKKQYSVVIGLIKKATSVVIATDADREGEMIARELLDLAG  120

Query  119  YRGPIERLWLSALNDASIRAALGKLRPSAETLSMYHSALARSRADWLVGMNLSRLFTVLG  178
            YRG I+R WLSAL+DASIR AL  L+++ ET ++Y ++++RSR+DWL+GMN+SRLFT+++
Sbjct  121  YRGQIQRCWLSALDDASIRKALQTLKSGKETEALYYAGMGRSRSDWLIGMNFSRLFTLMA  180

Query  179  RQAGYDG-VLSVGRVQTPTLKLVVDRDREIARFVSVPYWAIAVSLFA-GGSTFAAQWVPP  236
            +  GY G  LSVGRVQ+PTL LVV+RDREIA FV+ +  A+AV L + +G TF A    P
Sbjct  181  QAKGYSGKPLSVGRVQSPTLTLVVNRDREIANFVPKSHYALAVQLTTTSGETFVAGLAVP  240

Query  237  DACTDDAGRCLRQPVAQQTMQQIRAAGSAHVVSVETERVREGPPLPFDLGTLQEVCSKQL  296
            +   D++G CL   V QQ+  QI+ +G A VV+VET R + +PPL + L+ LQ  C++ +
Sbjct  241  EQYLDESGLCLDSRVIQQAEAQIKQTGLAKVVTVETKREKKSPPLLYALSDLQGECNRLF  300

Query  297  GLDVQETLEIAQALYETHKATTYPRSDSGYLPESMFAEVPTVLDSLLKTDPSLRSIMGQL  356
            G++ Q+ L+IAQ+LYE HK TTYPR+D GYLPES F++VP V+ SL+ +D++L++++ +L
Sbjct  301  GFGAQQVLDIAQSLYEEHKITTYPRTDCGYLPESQFSDVPNVIRSLVASDSGLQTLLPKL  360

Query  357  DRSQRSRAWNDGKVTAHHGIIPTLEPAKLSAMSEKELAVYRLIRSHYLAQFLPHHEFDRT  416
            +  Q+SRAW+D K+TAHHGIIPT+  A LS +SE E+ VY LIR +YLAQFLPH E D+T
Sbjct  361  NLRQKSRAWDDKKITAHHGIIPTIKKADLSKLSEEEMKVYDLIRRRYLAQFLPHLEMDKT  420

Query  417  VAKFSCGGQNLAATGKQVVIPGWRQVLAEPQAEDGDGEGDTAVRAQVLPALPKLYEGLAC  476
            VA +  +G+ L A G+ +V  GWR +++    E+ + +++     Q LP L K      C
Sbjct  421  VATLQSSGHTLVARGNVIVAQGWRILFGKNVDEETGNDDEK----QGLPVLTK---NQQC  473

Query  477  QVADVDLKALKTLPPKPYTQGELVKSMKGVAKLVSDPRLKQKLKDTVGIGTEATRANIIG  536
            +V++ ++++L+T PP  YT+G L+ +MK  A++V+DPRLKQ+L++T G+GTEATRA +I 
Sbjct  474  NVTHSEVRTLQTKPPAHYTEGTLLDAMKNAARFVTDPRLKQRLRETEGLGTEATRAGLIQ  533

Query  537  GLIARGYLVKKGRAIRASDAAFTLIDAVPAAIADPGTTAVWEQALDMIEAGQLTLDVFIG  596
            GLI +G+L+KK +++ AS  A +LID++P  + +PG TA+WEQAL+ I  G +TLD F+ 
Sbjct  534  GLIDKGFLLKKKKSLVASAEAVALIDSLPDLLKNPGLTALWEQALNQIAEGSMTLDAFMQ  593

Query  597  KQAAWISQLIAQYGSASLSIKVPQGPACPQCGAPTRQRSGKSGPFWSCSRYPDCKGTLPV  656
            KQ A + QLI+     ++S+   +   C++CG P R+ +   G FW+C+ YPDC+     
Sbjct  594  KQEAFVKQLIGSCMQQGMSLGNIEIRKCSECGKPMRKINHAKGTFWGCTGYPDCQ-----  648

Query  657  ESGSSKRGASRPRRSGRKGS  676
            +  + K+  S + +S++K+S
Sbjct  649  HKEADKKVKSASNKSAKKSS  668

> NC_016808_R1|63|G56|378773985|YP_005176228.1|Pasteurella_multocida_36950|-|54272..56323|topB1|Pmu_03290|DNA 
topoisomerase 
III
Length=683

 Score =  583 bits (2203),  Expect = 1e-167, Method: Compositional matrix adjust.
 Identities = 329/680 (49%), Positives = 488/680 (72%), Gaps = 16/680 (2%)

Query  1    MRLFLCEKPSQGKDIGRILGATQRGEGCLNGS--GVTVTWCIGHLVEAAPPEAYDEQLKR  58
            M+LF+CEKPSQ++D++ +LGAT +GEG L  +  ++ VTW +GHLVE   PE YDE  KR
Sbjct  1    MKLFICEKPSQARDLAGVLGATSKGEGLLATADKSIIVTWGFGHLVEQYQPEDYDEAWKR  60

Query  59   WSVEQLPIIPQHWRVEVKPKTATQFKVVKALLAKATHLVIATDADREGELIAREIVELCG  118
            W+ E LPIIP +W++  K  +  Q+ VV +L+ KAT +VIATDADREGE+IARE+++L G
Sbjct  61   WAFETLPIIPAQWKMTPKKESKKQYSVVIGLIKKATSVVIATDADREGEMIARELLDLAG  120

Query  119  YRGPIERLWLSALNDASIRAALGKLRPSAETLSMYHSALARSRADWLVGMNLSRLFTVLG  178
            YRG I+R WLSAL+DASIR AL  L+++ ET ++Y ++++RSR+DWL+GMN+SRLFT+++
Sbjct  121  YRGQIQRCWLSALDDASIRKALQTLKSGKETEALYYAGMGRSRSDWLIGMNFSRLFTLMA  180

Query  179  RQAGYDG-VLSVGRVQTPTLKLVVDRDREIARFVSVPYWAIAVSLFA-GGSTFAAQWVPP  236
            +  GY G  LSVGRVQ+PTL LVV+RDREIA FV+ +  A+AV L + +G TF A    P
Sbjct  181  QAKGYSGKPLSVGRVQSPTLTLVVNRDREIANFVPKSHYALAVQLTTTSGETFVAGLAVP  240

Query  237  DACTDDAGRCLRQPVAQQTMQQIRAAGSAHVVSVETERVREGPPLPFDLGTLQEVCSKQL  296
            +   D++G CL   V QQ+  QI+ +G A VV+VET R + +PPL + L+ LQ  C++ +
Sbjct  241  EQYLDESGLCLDSRVIQQAEAQIKQTGLAKVVTVETKREKKSPPLLYALSDLQGECNRLF  300

Query  297  GLDVQETLEIAQALYETHKATTYPRSDSGYLPESMFAEVPTVLDSLLKTDPSLRSIMGQL  356
            G++ Q+ L+IAQ+LYE HK TTYPR+D GYLPES F++VP V+ SL+ +D++L++++ +L
Sbjct  301  GFGAQQVLDIAQSLYEEHKITTYPRTDCGYLPESQFSDVPNVIRSLVASDSGLQTLLPKL  360

Query  357  DRSQRSRAWNDGKVTAHHGIIPTLEPAKLSAMSEKELAVYRLIRSHYLAQFLPHHEFDRT  416
            +  Q+SRAW+D K+TAHHGIIPT+  A LS +SE E+ VY LIR +YLAQFLPH E D+T
Sbjct  361  NLRQKSRAWDDKKITAHHGIIPTIKKADLSKLSEEEMKVYDLIRRRYLAQFLPHLEMDKT  420

Query  417  VAKFSCGGQNLAATGKQVVIPGWRQVLAEPQAEDGDGEGDTAVRAQVLPALPKLYEGLAC  476
            VA +  +G+ L A G+ +V  GWR +++    E+ + +++     Q LP L K      C
Sbjct  421  VATLQSSGHTLVARGNVIVAQGWRILFGKNVDEETGNDDEK----QGLPVLTK---NQQC  473

Query  477  QVADVDLKALKTLPPKPYTQGELVKSMKGVAKLVSDPRLKQKLKDTVGIGTEATRANIIG  536
            +V++ ++++L+T PP  YT+G L+ +MK  A++V+DPRLKQ+L++T G+GTEATRA +I 
Sbjct  474  NVTHSEVRTLQTKPPAHYTEGTLLDAMKNAARFVTDPRLKQRLRETEGLGTEATRAGLIQ  533

Query  537  GLIARGYLVKKGRAIRASDAAFTLIDAVPAAIADPGTTAVWEQALDMIEAGQLTLDVFIG  596
            GLI +G+L+KK +++ AS  A +LID++P  + +PG TA+WEQAL+ I  G +TLD F+ 
Sbjct  534  GLIDKGFLLKKKKSLVASAEAVALIDSLPDLLKNPGLTALWEQALNQIAEGSMTLDAFMQ  593

Query  597  KQAAWISQLIAQYGSASLSIKVPQGPACPQCGAPTRQRSGKSGPFWSCSRYPDCKGTLPV  656
            KQ A + QLI+     ++S+   +   C++CG P R+ +   G FW+C+ YPDC+     
Sbjct  594  KQEAFVKQLIGSCMQQGMSLGNIEIRKCSECGKPMRKINHAKGTFWGCTGYPDCQ-----  648

Query  657  ESGSSKRGASRPRRSGRKGS  676
            +  + K+  S + +S++K+S
Sbjct  649  HKEADKKVKSASNKSAKKSS  668

> NC_016808_R1|63|G56|378773985|YP_005176228.1|Pasteurella_multocida_36950|-|54272..56323|topB1|Pmu_03290|DNA 
topoisomerase 
III
Length=683

 Score =  583 bits (2203),  Expect = 1e-167, Method: Compositional matrix adjust.
 Identities = 329/680 (49%), Positives = 488/680 (72%), Gaps = 16/680 (2%)

Query  1    MRLFLCEKPSQGKDIGRILGATQRGEGCLNGS--GVTVTWCIGHLVEAAPPEAYDEQLKR  58
            M+LF+CEKPSQ++D++ +LGAT +GEG L  +  ++ VTW +GHLVE   PE YDE  KR
Sbjct  1    MKLFICEKPSQARDLAGVLGATSKGEGLLATADKSIIVTWGFGHLVEQYQPEDYDEAWKR  60

Query  59   WSVEQLPIIPQHWRVEVKPKTATQFKVVKALLAKATHLVIATDADREGELIAREIVELCG  118
            W+ E LPIIP +W++  K  +  Q+ VV +L+ KAT +VIATDADREGE+IARE+++L G
Sbjct  61   WAFETLPIIPAQWKMTPKKESKKQYSVVIGLIKKATSVVIATDADREGEMIARELLDLAG  120

Query  119  YRGPIERLWLSALNDASIRAALGKLRPSAETLSMYHSALARSRADWLVGMNLSRLFTVLG  178
            YRG I+R WLSAL+DASIR AL  L+++ ET ++Y ++++RSR+DWL+GMN+SRLFT+++
Sbjct  121  YRGQIQRCWLSALDDASIRKALQTLKSGKETEALYYAGMGRSRSDWLIGMNFSRLFTLMA  180

Query  179  RQAGYDG-VLSVGRVQTPTLKLVVDRDREIARFVSVPYWAIAVSLFA-GGSTFAAQWVPP  236
            +  GY G  LSVGRVQ+PTL LVV+RDREIA FV+ +  A+AV L + +G TF A    P
Sbjct  181  QAKGYSGKPLSVGRVQSPTLTLVVNRDREIANFVPKSHYALAVQLTTTSGETFVAGLAVP  240

Query  237  DACTDDAGRCLRQPVAQQTMQQIRAAGSAHVVSVETERVREGPPLPFDLGTLQEVCSKQL  296
            +   D++G CL   V QQ+  QI+ +G A VV+VET R + +PPL + L+ LQ  C++ +
Sbjct  241  EQYLDESGLCLDSRVIQQAEAQIKQTGLAKVVTVETKREKKSPPLLYALSDLQGECNRLF  300

Query  297  GLDVQETLEIAQALYETHKATTYPRSDSGYLPESMFAEVPTVLDSLLKTDPSLRSIMGQL  356
            G++ Q+ L+IAQ+LYE HK TTYPR+D GYLPES F++VP V+ SL+ +D++L++++ +L
Sbjct  301  GFGAQQVLDIAQSLYEEHKITTYPRTDCGYLPESQFSDVPNVIRSLVASDSGLQTLLPKL  360

Query  357  DRSQRSRAWNDGKVTAHHGIIPTLEPAKLSAMSEKELAVYRLIRSHYLAQFLPHHEFDRT  416
            +  Q+SRAW+D K+TAHHGIIPT+  A LS +SE E+ VY LIR +YLAQFLPH E D+T
Sbjct  361  NLRQKSRAWDDKKITAHHGIIPTIKKADLSKLSEEEMKVYDLIRRRYLAQFLPHLEMDKT  420

Query  417  VAKFSCGGQNLAATGKQVVIPGWRQVLAEPQAEDGDGEGDTAVRAQVLPALPKLYEGLAC  476
            VA +  +G+ L A G+ +V  GWR +++    E+ + +++     Q LP L K      C
Sbjct  421  VATLQSSGHTLVARGNVIVAQGWRILFGKNVDEETGNDDEK----QGLPVLTK---NQQC  473

Query  477  QVADVDLKALKTLPPKPYTQGELVKSMKGVAKLVSDPRLKQKLKDTVGIGTEATRANIIG  536
            +V++ ++++L+T PP  YT+G L+ +MK  A++V+DPRLKQ+L++T G+GTEATRA +I 
Sbjct  474  NVTHSEVRTLQTKPPAHYTEGTLLDAMKNAARFVTDPRLKQRLRETEGLGTEATRAGLIQ  533

Query  537  GLIARGYLVKKGRAIRASDAAFTLIDAVPAAIADPGTTAVWEQALDMIEAGQLTLDVFIG  596
            GLI +G+L+KK +++ AS  A +LID++P  + +PG TA+WEQAL+ I  G +TLD F+ 
Sbjct  534  GLIDKGFLLKKKKSLVASAEAVALIDSLPDLLKNPGLTALWEQALNQIAEGSMTLDAFMQ  593

Query  597  KQAAWISQLIAQYGSASLSIKVPQGPACPQCGAPTRQRSGKSGPFWSCSRYPDCKGTLPV  656
            KQ A + QLI+     ++S+   +   C++CG P R+ +   G FW+C+ YPDC+     
Sbjct  594  KQEAFVKQLIGSCMQQGMSLGNIEIRKCSECGKPMRKINHAKGTFWGCTGYPDCQ-----  648

Query  657  ESGSSKRGASRPRRSGRKGS  676
            +  + K+  S + +S++K+S
Sbjct  649  HKEADKKVKSASNKSAKKSS  668

> NC_016808_R1|63|G56|378773985|YP_005176228.1|Pasteurella_multocida_36950|-|54272..56323|topB1|Pmu_03290|DNA 
topoisomerase 
III
Length=683

 Score =  583 bits (2203),  Expect = 1e-167, Method: Compositional matrix adjust.
 Identities = 329/680 (49%), Positives = 488/680 (72%), Gaps = 16/680 (2%)

Query  1    MRLFLCEKPSQGKDIGRILGATQRGEGCLNGS--GVTVTWCIGHLVEAAPPEAYDEQLKR  58
            M+LF+CEKPSQ++D++ +LGAT +GEG L  +  ++ VTW +GHLVE   PE YDE  KR
Sbjct  1    MKLFICEKPSQARDLAGVLGATSKGEGLLATADKSIIVTWGFGHLVEQYQPEDYDEAWKR  60

Query  59   WSVEQLPIIPQHWRVEVKPKTATQFKVVKALLAKATHLVIATDADREGELIAREIVELCG  118
            W+ E LPIIP +W++  K  +  Q+ VV +L+ KAT +VIATDADREGE+IARE+++L G
Sbjct  61   WAFETLPIIPAQWKMTPKKESKKQYSVVIGLIKKATSVVIATDADREGEMIARELLDLAG  120

Query  119  YRGPIERLWLSALNDASIRAALGKLRPSAETLSMYHSALARSRADWLVGMNLSRLFTVLG  178
            YRG I+R WLSAL+DASIR AL  L+++ ET ++Y ++++RSR+DWL+GMN+SRLFT+++
Sbjct  121  YRGQIQRCWLSALDDASIRKALQTLKSGKETEALYYAGMGRSRSDWLIGMNFSRLFTLMA  180

Query  179  RQAGYDG-VLSVGRVQTPTLKLVVDRDREIARFVSVPYWAIAVSLFA-GGSTFAAQWVPP  236
            +  GY G  LSVGRVQ+PTL LVV+RDREIA FV+ +  A+AV L + +G TF A    P
Sbjct  181  QAKGYSGKPLSVGRVQSPTLTLVVNRDREIANFVPKSHYALAVQLTTTSGETFVAGLAVP  240

Query  237  DACTDDAGRCLRQPVAQQTMQQIRAAGSAHVVSVETERVREGPPLPFDLGTLQEVCSKQL  296
            +   D++G CL   V QQ+  QI+ +G A VV+VET R + +PPL + L+ LQ  C++ +
Sbjct  241  EQYLDESGLCLDSRVIQQAEAQIKQTGLAKVVTVETKREKKSPPLLYALSDLQGECNRLF  300

Query  297  GLDVQETLEIAQALYETHKATTYPRSDSGYLPESMFAEVPTVLDSLLKTDPSLRSIMGQL  356
            G++ Q+ L+IAQ+LYE HK TTYPR+D GYLPES F++VP V+ SL+ +D++L++++ +L
Sbjct  301  GFGAQQVLDIAQSLYEEHKITTYPRTDCGYLPESQFSDVPNVIRSLVASDSGLQTLLPKL  360

Query  357  DRSQRSRAWNDGKVTAHHGIIPTLEPAKLSAMSEKELAVYRLIRSHYLAQFLPHHEFDRT  416
            +  Q+SRAW+D K+TAHHGIIPT+  A LS +SE E+ VY LIR +YLAQFLPH E D+T
Sbjct  361  NLRQKSRAWDDKKITAHHGIIPTIKKADLSKLSEEEMKVYDLIRRRYLAQFLPHLEMDKT  420

Query  417  VAKFSCGGQNLAATGKQVVIPGWRQVLAEPQAEDGDGEGDTAVRAQVLPALPKLYEGLAC  476
            VA +  +G+ L A G+ +V  GWR +++    E+ + +++     Q LP L K      C
Sbjct  421  VATLQSSGHTLVARGNVIVAQGWRILFGKNVDEETGNDDEK----QGLPVLTK---NQQC  473

Query  477  QVADVDLKALKTLPPKPYTQGELVKSMKGVAKLVSDPRLKQKLKDTVGIGTEATRANIIG  536
            +V++ ++++L+T PP  YT+G L+ +MK  A++V+DPRLKQ+L++T G+GTEATRA +I 
Sbjct  474  NVTHSEVRTLQTKPPAHYTEGTLLDAMKNAARFVTDPRLKQRLRETEGLGTEATRAGLIQ  533

Query  537  GLIARGYLVKKGRAIRASDAAFTLIDAVPAAIADPGTTAVWEQALDMIEAGQLTLDVFIG  596
            GLI +G+L+KK +++ AS  A +LID++P  + +PG TA+WEQAL+ I  G +TLD F+ 
Sbjct  534  GLIDKGFLLKKKKSLVASAEAVALIDSLPDLLKNPGLTALWEQALNQIAEGSMTLDAFMQ  593

Query  597  KQAAWISQLIAQYGSASLSIKVPQGPACPQCGAPTRQRSGKSGPFWSCSRYPDCKGTLPV  656
            KQ A + QLI+     ++S+   +   C++CG P R+ +   G FW+C+ YPDC+     
Sbjct  594  KQEAFVKQLIGSCMQQGMSLGNIEIRKCSECGKPMRKINHAKGTFWGCTGYPDCQ-----  648

Query  657  ESGSSKRGASRPRRSGRKGS  676
            +  + K+  S + +S++K+S
Sbjct  649  HKEADKKVKSASNKSAKKSS  668

> NC_016808_R1|63|G56|378773985|YP_005176228.1|Pasteurella_multocida_36950|-|54272..56323|topB1|Pmu_03290|DNA 
topoisomerase 
III
Length=683

 Score =  583 bits (2203),  Expect = 1e-167, Method: Compositional matrix adjust.
 Identities = 329/680 (49%), Positives = 488/680 (72%), Gaps = 16/680 (2%)

Query  1    MRLFLCEKPSQGKDIGRILGATQRGEGCLNGS--GVTVTWCIGHLVEAAPPEAYDEQLKR  58
            M+LF+CEKPSQ++D++ +LGAT +GEG L  +  ++ VTW +GHLVE   PE YDE  KR
Sbjct  1    MKLFICEKPSQARDLAGVLGATSKGEGLLATADKSIIVTWGFGHLVEQYQPEDYDEAWKR  60

Query  59   WSVEQLPIIPQHWRVEVKPKTATQFKVVKALLAKATHLVIATDADREGELIAREIVELCG  118
            W+ E LPIIP +W++  K  +  Q+ VV +L+ KAT +VIATDADREGE+IARE+++L G
Sbjct  61   WAFETLPIIPAQWKMTPKKESKKQYSVVIGLIKKATSVVIATDADREGEMIARELLDLAG  120

Query  119  YRGPIERLWLSALNDASIRAALGKLRPSAETLSMYHSALARSRADWLVGMNLSRLFTVLG  178
            YRG I+R WLSAL+DASIR AL  L+++ ET ++Y ++++RSR+DWL+GMN+SRLFT+++
Sbjct  121  YRGQIQRCWLSALDDASIRKALQTLKSGKETEALYYAGMGRSRSDWLIGMNFSRLFTLMA  180

Query  179  RQAGYDG-VLSVGRVQTPTLKLVVDRDREIARFVSVPYWAIAVSLFA-GGSTFAAQWVPP  236
            +  GY G  LSVGRVQ+PTL LVV+RDREIA FV+ +  A+AV L + +G TF A    P
Sbjct  181  QAKGYSGKPLSVGRVQSPTLTLVVNRDREIANFVPKSHYALAVQLTTTSGETFVAGLAVP  240

Query  237  DACTDDAGRCLRQPVAQQTMQQIRAAGSAHVVSVETERVREGPPLPFDLGTLQEVCSKQL  296
            +   D++G CL   V QQ+  QI+ +G A VV+VET R + +PPL + L+ LQ  C++ +
Sbjct  241  EQYLDESGLCLDSRVIQQAEAQIKQTGLAKVVTVETKREKKSPPLLYALSDLQGECNRLF  300

Query  297  GLDVQETLEIAQALYETHKATTYPRSDSGYLPESMFAEVPTVLDSLLKTDPSLRSIMGQL  356
            G++ Q+ L+IAQ+LYE HK TTYPR+D GYLPES F++VP V+ SL+ +D++L++++ +L
Sbjct  301  GFGAQQVLDIAQSLYEEHKITTYPRTDCGYLPESQFSDVPNVIRSLVASDSGLQTLLPKL  360

Query  357  DRSQRSRAWNDGKVTAHHGIIPTLEPAKLSAMSEKELAVYRLIRSHYLAQFLPHHEFDRT  416
            +  Q+SRAW+D K+TAHHGIIPT+  A LS +SE E+ VY LIR +YLAQFLPH E D+T
Sbjct  361  NLRQKSRAWDDKKITAHHGIIPTIKKADLSKLSEEEMKVYDLIRRRYLAQFLPHLEMDKT  420

Query  417  VAKFSCGGQNLAATGKQVVIPGWRQVLAEPQAEDGDGEGDTAVRAQVLPALPKLYEGLAC  476
            VA +  +G+ L A G+ +V  GWR +++    E+ + +++     Q LP L K      C
Sbjct  421  VATLQSSGHTLVARGNVIVAQGWRILFGKNVDEETGNDDEK----QGLPVLTK---NQQC  473

Query  477  QVADVDLKALKTLPPKPYTQGELVKSMKGVAKLVSDPRLKQKLKDTVGIGTEATRANIIG  536
            +V++ ++++L+T PP  YT+G L+ +MK  A++V+DPRLKQ+L++T G+GTEATRA +I 
Sbjct  474  NVTHSEVRTLQTKPPAHYTEGTLLDAMKNAARFVTDPRLKQRLRETEGLGTEATRAGLIQ  533

Query  537  GLIARGYLVKKGRAIRASDAAFTLIDAVPAAIADPGTTAVWEQALDMIEAGQLTLDVFIG  596
            GLI +G+L+KK +++ AS  A +LID++P  + +PG TA+WEQAL+ I  G +TLD F+ 
Sbjct  534  GLIDKGFLLKKKKSLVASAEAVALIDSLPDLLKNPGLTALWEQALNQIAEGSMTLDAFMQ  593

Query  597  KQAAWISQLIAQYGSASLSIKVPQGPACPQCGAPTRQRSGKSGPFWSCSRYPDCKGTLPV  656
            KQ A + QLI+     ++S+   +   C++CG P R+ +   G FW+C+ YPDC+     
Sbjct  594  KQEAFVKQLIGSCMQQGMSLGNIEIRKCSECGKPMRKINHAKGTFWGCTGYPDCQ-----  648

Query  657  ESGSSKRGASRPRRSGRKGS  676
            +  + K+  S + +S++K+S
Sbjct  649  HKEADKKVKSASNKSAKKSS  668

> NC_016808_R1|63|G56|378773985|YP_005176228.1|Pasteurella_multocida_36950|-|54272..56323|topB1|Pmu_03290|DNA 
topoisomerase 
III
Length=683

 Score =  583 bits (2203),  Expect = 1e-167, Method: Compositional matrix adjust.
 Identities = 329/680 (49%), Positives = 488/680 (72%), Gaps = 16/680 (2%)

Query  1    MRLFLCEKPSQGKDIGRILGATQRGEGCLNGS--GVTVTWCIGHLVEAAPPEAYDEQLKR  58
            M+LF+CEKPSQ++D++ +LGAT +GEG L  +  ++ VTW +GHLVE   PE YDE  KR
Sbjct  1    MKLFICEKPSQARDLAGVLGATSKGEGLLATADKSIIVTWGFGHLVEQYQPEDYDEAWKR  60

Query  59   WSVEQLPIIPQHWRVEVKPKTATQFKVVKALLAKATHLVIATDADREGELIAREIVELCG  118
            W+ E LPIIP +W++  K  +  Q+ VV +L+ KAT +VIATDADREGE+IARE+++L G
Sbjct  61   WAFETLPIIPAQWKMTPKKESKKQYSVVIGLIKKATSVVIATDADREGEMIARELLDLAG  120

Query  119  YRGPIERLWLSALNDASIRAALGKLRPSAETLSMYHSALARSRADWLVGMNLSRLFTVLG  178
            YRG I+R WLSAL+DASIR AL  L+++ ET ++Y ++++RSR+DWL+GMN+SRLFT+++
Sbjct  121  YRGQIQRCWLSALDDASIRKALQTLKSGKETEALYYAGMGRSRSDWLIGMNFSRLFTLMA  180

Query  179  RQAGYDG-VLSVGRVQTPTLKLVVDRDREIARFVSVPYWAIAVSLFA-GGSTFAAQWVPP  236
            +  GY G  LSVGRVQ+PTL LVV+RDREIA FV+ +  A+AV L + +G TF A    P
Sbjct  181  QAKGYSGKPLSVGRVQSPTLTLVVNRDREIANFVPKSHYALAVQLTTTSGETFVAGLAVP  240

Query  237  DACTDDAGRCLRQPVAQQTMQQIRAAGSAHVVSVETERVREGPPLPFDLGTLQEVCSKQL  296
            +   D++G CL   V QQ+  QI+ +G A VV+VET R + +PPL + L+ LQ  C++ +
Sbjct  241  EQYLDESGLCLDSRVIQQAEAQIKQTGLAKVVTVETKREKKSPPLLYALSDLQGECNRLF  300

Query  297  GLDVQETLEIAQALYETHKATTYPRSDSGYLPESMFAEVPTVLDSLLKTDPSLRSIMGQL  356
            G++ Q+ L+IAQ+LYE HK TTYPR+D GYLPES F++VP V+ SL+ +D++L++++ +L
Sbjct  301  GFGAQQVLDIAQSLYEEHKITTYPRTDCGYLPESQFSDVPNVIRSLVASDSGLQTLLPKL  360

Query  357  DRSQRSRAWNDGKVTAHHGIIPTLEPAKLSAMSEKELAVYRLIRSHYLAQFLPHHEFDRT  416
            +  Q+SRAW+D K+TAHHGIIPT+  A LS +SE E+ VY LIR +YLAQFLPH E D+T
Sbjct  361  NLRQKSRAWDDKKITAHHGIIPTIKKADLSKLSEEEMKVYDLIRRRYLAQFLPHLEMDKT  420

Query  417  VAKFSCGGQNLAATGKQVVIPGWRQVLAEPQAEDGDGEGDTAVRAQVLPALPKLYEGLAC  476
            VA +  +G+ L A G+ +V  GWR +++    E+ + +++     Q LP L K      C
Sbjct  421  VATLQSSGHTLVARGNVIVAQGWRILFGKNVDEETGNDDEK----QGLPVLTK---NQQC  473

Query  477  QVADVDLKALKTLPPKPYTQGELVKSMKGVAKLVSDPRLKQKLKDTVGIGTEATRANIIG  536
            +V++ ++++L+T PP  YT+G L+ +MK  A++V+DPRLKQ+L++T G+GTEATRA +I 
Sbjct  474  NVTHSEVRTLQTKPPAHYTEGTLLDAMKNAARFVTDPRLKQRLRETEGLGTEATRAGLIQ  533

Query  537  GLIARGYLVKKGRAIRASDAAFTLIDAVPAAIADPGTTAVWEQALDMIEAGQLTLDVFIG  596
            GLI +G+L+KK +++ AS  A +LID++P  + +PG TA+WEQAL+ I  G +TLD F+ 
Sbjct  534  GLIDKGFLLKKKKSLVASAEAVALIDSLPDLLKNPGLTALWEQALNQIAEGSMTLDAFMQ  593

Query  597  KQAAWISQLIAQYGSASLSIKVPQGPACPQCGAPTRQRSGKSGPFWSCSRYPDCKGTLPV  656
            KQ A + QLI+     ++S+   +   C++CG P R+ +   G FW+C+ YPDC+     
Sbjct  594  KQEAFVKQLIGSCMQQGMSLGNIEIRKCSECGKPMRKINHAKGTFWGCTGYPDCQ-----  648

Query  657  ESGSSKRGASRPRRSGRKGS  676
            +  + K+  S + +S++K+S
Sbjct  649  HKEADKKVKSASNKSAKKSS  668

> NC_016808_R1|63|G56|378773985|YP_005176228.1|Pasteurella_multocida_36950|-|54272..56323|topB1|Pmu_03290|DNA 
topoisomerase 
III
Length=683

 Score =  583 bits (2202),  Expect = 1e-167, Method: Compositional matrix adjust.
 Identities = 329/680 (49%), Positives = 488/680 (72%), Gaps = 16/680 (2%)

Query  1    MRLFLCEKPSQGKDIGRILGATQRGEGCLNGS--GVTVTWCIGHLVEAAPPEAYDEQLKR  58
            M+LF+CEKPSQ++D++ +LGAT +GEG L  +  ++ VTW +GHLVE   PE YDE  KR
Sbjct  1    MKLFICEKPSQARDLAGVLGATSKGEGLLATADKSIIVTWGFGHLVEQYQPEDYDEAWKR  60

Query  59   WSVEQLPIIPQHWRVEVKPKTATQFKVVKALLAKATHLVIATDADREGELIAREIVELCG  118
            W+ E LPIIP +W++  K  +  Q+ VV +L+ KAT +VIATDADREGE+IARE+++L G
Sbjct  61   WAFETLPIIPAQWKMTPKKESKKQYSVVIGLIKKATSVVIATDADREGEMIARELLDLAG  120

Query  119  YRGPIERLWLSALNDASIRAALGQLRPSAETLSMYHSALARSRADWLVGMNLSRLFTVLG  178
            YRG I+R WLSAL+DASIR AL  L+++ ET ++Y ++++RSR+DWL+GMN+SRLFT+++
Sbjct  121  YRGQIQRCWLSALDDASIRKALQTLKSGKETEALYYAGMGRSRSDWLIGMNFSRLFTLMA  180

Query  179  RQAGYDG-VLSVGRVQTPTLKLVVDRDREIARFVSVPYWAIAVSLFA-GGSTFAAQWVPP  236
            +  GY G  LSVGRVQ+PTL LVV+RDREIA FV+ +  A+AV L + +G TF A    P
Sbjct  181  QAKGYSGKPLSVGRVQSPTLTLVVNRDREIANFVPKSHYALAVQLTTTSGETFVAGLAVP  240

Query  237  DACTDDAGRCLRQPVAQQTMQQIRAAGSAHVVSVETERVREGPPLPFDLGTLQEVCSKQL  296
            +   D++G CL   V QQ+  QI+ +G A VV+VET R + +PPL + L+ LQ  C++ +
Sbjct  241  EQYLDESGLCLDSRVIQQAEAQIKQTGLAKVVTVETKREKKSPPLLYALSDLQGECNRLF  300

Query  297  GLDVQETLEIAQALYETHKATTYPRSDSGYLPESMFAEVPTVLDSLLKTDPSLRSIMGQL  356
            G++ Q+ L+IAQ+LYE HK TTYPR+D GYLPES F++VP V+ SL+ +D++L++++ +L
Sbjct  301  GFGAQQVLDIAQSLYEEHKITTYPRTDCGYLPESQFSDVPNVIRSLVASDSGLQTLLPKL  360

Query  357  DRSQRSRAWNDGKVTAHHGIIPTLEPAKLSAMSEKELAVYRLIRSHYLAQFLPHHEFDRT  416
            +  Q+SRAW+D K+TAHHGIIPT+  A LS +SE E+ VY LIR +YLAQFLPH E D+T
Sbjct  361  NLRQKSRAWDDKKITAHHGIIPTIKKADLSKLSEEEMKVYDLIRRRYLAQFLPHLEMDKT  420

Query  417  VAKFSCGGQNLAATGKQVVIPGWRQVLAEPQAEDGDGEGDTAVRAQVLPALPKLYEGLAC  476
            VA +  +G+ L A G+ +V  GWR +++    E+ + +++     Q LP L K      C
Sbjct  421  VATLQSSGHTLVARGNVIVAQGWRILFGKNVDEETGNDDEK----QGLPVLTK---NQQC  473

Query  477  QVADVDLKALKTLPPKPYTQGELVKSMKGVAKLVSDPRLKQKLKDTVGIGTEATRANIIG  536
            +V++ ++++L+T PP  YT+G L+ +MK  A++V+DPRLKQ+L++T G+GTEATRA +I 
Sbjct  474  NVTHSEVRTLQTKPPAHYTEGTLLDAMKNAARFVTDPRLKQRLRETEGLGTEATRAGLIQ  533

Query  537  GLIARGYLVKKGRAIRASDAAFTLIDAVPAAIADPGTTAVWEQALDMIEAGQLTLDVFIG  596
            GLI +G+L+KK +++ AS  A +LID++P  + +PG TA+WEQAL+ I  G +TLD F+ 
Sbjct  534  GLIDKGFLLKKKKSLVASAEAVALIDSLPDLLKNPGLTALWEQALNQIAEGSMTLDAFMQ  593

Query  597  KQAAWISQLIAQYGSASLSIKVPQGPACPQCGAPTRQRSGKSGPFWSCSRYPDCKGTLPV  656
            KQ A + QLI+     ++S+   +   C++CG P R+ +   G FW+C+ YPDC+     
Sbjct  594  KQEAFVKQLIGSCMQQGMSLGNIEIRKCSECGKPMRKINHAKGTFWGCTGYPDCQ-----  648

Query  657  ESGSSKRGASRPRRSGRKGS  676
            +  + K+  S + +S++K+S
Sbjct  649  HKEADKKVKSASNKSAKKSS  668

> NC_016808_R1|63|G56|378773985|YP_005176228.1|Pasteurella_multocida_36950|-|54272..56323|topB1|Pmu_03290|DNA 
topoisomerase 
III
Length=683

 Score =  582 bits (2197),  Expect = 3e-167, Method: Compositional matrix adjust.
 Identities = 328/674 (49%), Positives = 492/674 (73%), Gaps = 10/674 (1%)

Query  1    MRLFLCEKPSQGKDIGRILGATQRGEGCLNGS--GVTVTWCIGHLVEAAAPEAYDEQLKR  58
            M+LF+CEKPSQ++D++ +LGAT +GEG L  +  ++ VTW +GHLVE   PE YDE  KR
Sbjct  1    MKLFICEKPSQARDLAGVLGATSKGEGLLATADKSIIVTWGFGHLVEQYQPEDYDEAWKR  60

Query  59   WSIEQLPIIPQNWRVEVKPKTATQFKVVKALLAKATQLVIATDADREGELIAREIIELCG  118
            W++E LPIIP +W++  K  +  Q+ VV +L+ KAT +VIATDADREGE+IARE+++L G
Sbjct  61   WAFETLPIIPAQWKMTPKKESKKQYSVVIGLIKKATSVVIATDADREGEMIARELLDLAG  120

Query  119  YRGPIERLWLSALNDASIRAALGKLRPSAETLPMYYSALARSRADWLVGMNLSRLFTVLG  178
            YRG I+R WLSAL+DASIR AL  L+++ ET ++YY++++RSR+DWL+GMN+SRLFT+++
Sbjct  121  YRGQIQRCWLSALDDASIRKALQTLKSGKETEALYYAGMGRSRSDWLIGMNFSRLFTLMA  180

Query  179  RQAGYDG-VLSVGRVQTPTLKLVVDRDREIAAFVSVPYWAIDVSLSA-SGQSFTAQWVPP  236
            +  GY G  LSVGRVQ+PTL LVV+RDREIA FV+ +  A+ V L++ SG++F A    P
Sbjct  181  QAKGYSGKPLSVGRVQSPTLTLVVNRDREIANFVPKSHYALAVQLTTTSGETFVAGLAVP  240

Query  237  DAYTDDTGRCLQQPVaqraaqqirgagsaqVVSVETERVREGPPLLFDLGTLQEVCSKQL  296
            + Y D++G CL+  V Q+A  QI+ +G A+VV+VET R + +PPLL+ L+ LQ  C++ +
Sbjct  241  EQYLDESGLCLDSRVIQQAEAQIKQTGLAKVVTVETKREKKSPPLLYALSDLQGECNRLF  300

Query  297  GLDVQETLEIAQALYETHKATTYPRSDSGYLPESMFAEVSTVLDSLLRTDPSLRPIMDQL  356
            G++ Q+ L+IAQ+LYE HK TTYPR+D GYLPES F++V+ V+ SL+ +D++L+ ++ +L
Sbjct  301  GFGAQQVLDIAQSLYEEHKITTYPRTDCGYLPESQFSDVPNVIRSLVASDSGLQTLLPKL  360

Query  357  DRSQRSRAWNDGKVTAHHGIIPTLEPANLSAMSEKELAVYRLIRAHYLAQFLPHHEFDRT  416
            +  Q+SRAW+D K+TAHHGIIPT+  A+LS +SE E+ VY LIR +YLAQFLPH E D+T
Sbjct  361  NLRQKSRAWDDKKITAHHGIIPTIKKADLSKLSEEEMKVYDLIRRRYLAQFLPHLEMDKT  420

Query  417  VANLACGQQKLAATGKQVVVKGWPLVLTEPQPDEDGDAAARSQVLPALREGLACLVADVD  476
            VA L  + + L A G+ +V +GW +++     +E G+   + Q LP L     C V++ +
Sbjct  421  VATLQSSGHTLVARGNVIVAQGWRILFGKNVDEETGNDDEK-QGLPVLTKNQQCNVTHSE  479

Query  477  LKALKTLPPRPYTQGELVKSMKGVAKLVTDPRLKQKFRDTVGIGTEATRANIISGLIARG  536
            +++L+T PP  YT+G L+ +MK  A++VTDPRLKQ++R+T G+GTEATRA +I GLI +G
Sbjct  480  VRTLQTKPPAHYTEGTLLDAMKNAARFVTDPRLKQRLRETEGLGTEATRAGLIQGLIDKG  539

Query  537  YIVKKGRAIRASDAAFTLIDAVPAAIADPGTTAVWEQALDMIEAGQLTLDVFIGKQAAWI  596
            +++KK +++ AS  A +LID++P  + +PG TA+WEQAL+ I  G +TLD F+ KQ A +
Sbjct  540  FLLKKKKSLVASAEAVALIDSLPDLLKNPGLTALWEQALNQIAEGSMTLDAFMQKQEAFV  599

Query  597  SQLIAQYSIASLSIKVPQGPACPQCGAPTRQRSGKSGPFWSCSRYPDCKGTLPVESGTSK  656
             QLI+     ++S+   +   C++CG P R+ +   G FW+C+ YPDC+     +  + K
Sbjct  600  KQLIGSCMQQGMSLGNIEIRKCSECGKPMRKINHAKGTFWGCTGYPDCQ-----HKEADK  654

Query  657  RGASRPHRSGRQGS  670
            +  S +++S++++S
Sbjct  655  KVKSASNKSAKKSS  668

> NC_016808_R1|63|G56|378773985|YP_005176228.1|Pasteurella_multocida_36950|-|54272..56323|topB1|Pmu_03290|DNA 
topoisomerase 
III
Length=683

 Score =  582 bits (2197),  Expect = 3e-167, Method: Compositional matrix adjust.
 Identities = 328/674 (49%), Positives = 492/674 (73%), Gaps = 10/674 (1%)

Query  1    MRLFLCEKPSQGKDIGRILGATQRGEGCLNGS--GVTVTWCIGHLVEAAAPEAYDEQLKR  58
            M+LF+CEKPSQ++D++ +LGAT +GEG L  +  ++ VTW +GHLVE   PE YDE  KR
Sbjct  1    MKLFICEKPSQARDLAGVLGATSKGEGLLATADKSIIVTWGFGHLVEQYQPEDYDEAWKR  60

Query  59   WSIEQLPIIPQNWRVEVKPKTATQFKVVKALLAKATQLVIATDADREGELIAREIIELCG  118
            W++E LPIIP +W++  K  +  Q+ VV +L+ KAT +VIATDADREGE+IARE+++L G
Sbjct  61   WAFETLPIIPAQWKMTPKKESKKQYSVVIGLIKKATSVVIATDADREGEMIARELLDLAG  120

Query  119  YRGPIERLWLSALNDASIRAALGKLRPSAETLPMYYSALARSRADWLVGMNLSRLFTVLG  178
            YRG I+R WLSAL+DASIR AL  L+++ ET ++YY++++RSR+DWL+GMN+SRLFT+++
Sbjct  121  YRGQIQRCWLSALDDASIRKALQTLKSGKETEALYYAGMGRSRSDWLIGMNFSRLFTLMA  180

Query  179  RQAGYDG-VLSVGRVQTPTLKLVVDRDREIAAFVSVPYWAIDVSLSA-SGQSFTAQWVPP  236
            +  GY G  LSVGRVQ+PTL LVV+RDREIA FV+ +  A+ V L++ SG++F A    P
Sbjct  181  QAKGYSGKPLSVGRVQSPTLTLVVNRDREIANFVPKSHYALAVQLTTTSGETFVAGLAVP  240

Query  237  DAYTDDTGRCLQQPVaqraaqqirgagsaqVVSVETERVREGPPLLFDLGTLQEVCSKQL  296
            + Y D++G CL+  V Q+A  QI+ +G A+VV+VET R + +PPLL+ L+ LQ  C++ +
Sbjct  241  EQYLDESGLCLDSRVIQQAEAQIKQTGLAKVVTVETKREKKSPPLLYALSDLQGECNRLF  300

Query  297  GLDVQETLEIAQALYETHKATTYPRSDSGYLPESMFAEVSTVLDSLLRTDPSLRPIMDQL  356
            G++ Q+ L+IAQ+LYE HK TTYPR+D GYLPES F++V+ V+ SL+ +D++L+ ++ +L
Sbjct  301  GFGAQQVLDIAQSLYEEHKITTYPRTDCGYLPESQFSDVPNVIRSLVASDSGLQTLLPKL  360

Query  357  DRSQRSRAWNDGKVTAHHGIIPTLEPANLSAMSEKELAVYRLIRAHYLAQFLPHHEFDRT  416
            +  Q+SRAW+D K+TAHHGIIPT+  A+LS +SE E+ VY LIR +YLAQFLPH E D+T
Sbjct  361  NLRQKSRAWDDKKITAHHGIIPTIKKADLSKLSEEEMKVYDLIRRRYLAQFLPHLEMDKT  420

Query  417  VANLACGQQKLAATGKQVVVKGWPLVLTEPQPDEDGDAAARSQVLPALREGLACLVADVD  476
            VA L  + + L A G+ +V +GW +++     +E G+   + Q LP L     C V++ +
Sbjct  421  VATLQSSGHTLVARGNVIVAQGWRILFGKNVDEETGNDDEK-QGLPVLTKNQQCNVTHSE  479

Query  477  LKALKTLPPRPYTQGELVKSMKGVAKLVTDPRLKQKFRDTVGIGTEATRANIISGLIARG  536
            +++L+T PP  YT+G L+ +MK  A++VTDPRLKQ++R+T G+GTEATRA +I GLI +G
Sbjct  480  VRTLQTKPPAHYTEGTLLDAMKNAARFVTDPRLKQRLRETEGLGTEATRAGLIQGLIDKG  539

Query  537  YIVKKGRAIRASDAAFTLIDAVPAAIADPGTTAVWEQALDMIEAGQLTLDVFIGKQAAWI  596
            +++KK +++ AS  A +LID++P  + +PG TA+WEQAL+ I  G +TLD F+ KQ A +
Sbjct  540  FLLKKKKSLVASAEAVALIDSLPDLLKNPGLTALWEQALNQIAEGSMTLDAFMQKQEAFV  599

Query  597  SQLIAQYSIASLSIKVPQGPACPQCGAPTRQRSGKSGPFWSCSRYPDCKGTLPVESGTSK  656
             QLI+     ++S+   +   C++CG P R+ +   G FW+C+ YPDC+     +  + K
Sbjct  600  KQLIGSCMQQGMSLGNIEIRKCSECGKPMRKINHAKGTFWGCTGYPDCQ-----HKEADK  654

Query  657  RGASRPHRSGRQGS  670
            +  S +++S++++S
Sbjct  655  KVKSASNKSAKKSS  668

> NC_016808_R1|63|G56|378773985|YP_005176228.1|Pasteurella_multocida_36950|-|54272..56323|topB1|Pmu_03290|DNA 
topoisomerase 
III
Length=683

 Score =  581 bits (2196),  Expect = 3e-167, Method: Compositional matrix adjust.
 Identities = 332/674 (50%), Positives = 492/674 (73%), Gaps = 10/674 (1%)

Query  1    MRLFLCEKPSQGKDIGRILGATQRGEGCLSGS--GVTVTWCIGHLVEAAAPEVYDAALKR  58
            M+LF+CEKPSQ++D++ +LGAT +GEG L+ +  ++ VTW +GHLVE   PE YD A KR
Sbjct  1    MKLFICEKPSQARDLAGVLGATSKGEGLLATADKSIIVTWGFGHLVEQYQPEDYDEAWKR  60

Query  59   WSLEQLPIVPQQWRVEVKPKTATQFKVVKALLAKATHLVIATDADREGELIAREIIDLCG  118
            W++E LPI+P QW++  K  +  Q+ VV +L+ KAT +VIATDADREGE+IARE++DL G
Sbjct  61   WAFETLPIIPAQWKMTPKKESKKQYSVVIGLIKKATSVVIATDADREGEMIARELLDLAG  120

Query  119  YRGPIERLWLSALNDASIRTALGKLRPSSDTLPMYYSALARSRADWLVGMNLSRLFTVLG  178
            YRG I+R WLSAL+DASIR AL  L+++ +T ++YY++++RSR+DWL+GMN+SRLFT+++
Sbjct  121  YRGQIQRCWLSALDDASIRKALQTLKSGKETEALYYAGMGRSRSDWLIGMNFSRLFTLMA  180

Query  179  RQAGYDG-VLSVGRVQTPTLKLVVDRDREIAAFKSVPFWAIDVSLSA-GGQAFSAQWVPP  236
            +  GY G  LSVGRVQ+PTL LVV+RDREIA F + +  A+ V L++ +G++F A    P
Sbjct  181  QAKGYSGKPLSVGRVQSPTLTLVVNRDREIANFVPKSHYALAVQLTTTSGETFVAGLAVP  240

Query  237  DGCTDDAGRCLqqpiaqqaaqqiraassaqVVSVETERVREGPPLLFDLGTLQEVCSKQL  296
            +   D++G CL+  + QQA  QI+ ++ A+VV+VET R + +PPLL+ L+ LQ  C++ +
Sbjct  241  EQYLDESGLCLDSRVIQQAEAQIKQTGLAKVVTVETKREKKSPPLLYALSDLQGECNRLF  300

Query  297  GLDVQETLEIAQALYETHKATTYPRSDSGYLPESMFAEVPTVLDSLLKTDPSLRPIMGQL  356
            G++ Q+ L+IAQ+LYE HK TTYPR+D GYLPES F++VP V+ SL+ +D++L+ ++ +L
Sbjct  301  GFGAQQVLDIAQSLYEEHKITTYPRTDCGYLPESQFSDVPNVIRSLVASDSGLQTLLPKL  360

Query  357  DRSQRSRAWNDGKVTAHHGIIPTLEPANLSAMSEKELAVYWLIRAHYLAQFLPHHEFDRT  416
            +  Q+SRAW+D K+TAHHGIIPT+  A+LS +SE E+ VY LIR +YLAQFLPH E D+T
Sbjct  361  NLRQKSRAWDDKKITAHHGIIPTIKKADLSKLSEEEMKVYDLIRRRYLAQFLPHLEMDKT  420

Query  417  IAELSCGQQKLVATGKQVAAQGWHLVLAEPQADEDGETTARSQVLPALREGLACQVAEAE  476
            +A L  + + LVA G+ + AQGW+++++    +E G+   + Q LP L     C+V+++E
Sbjct  421  VATLQSSGHTLVARGNVIVAQGWRILFGKNVDEETGNDDEK-QGLPVLTKNQQCNVTHSE  479

Query  477  VKALKTLPPKPYTQGELVKSMKGVARFVTDPRLKQKLKDTTGIGTEATRANIITGLLTRG  536
            V++L+T PP  YT+G L+ +MK  ARFVTDPRLKQ+L++T G+GTEATRA +I GL+ +G
Sbjct  480  VRTLQTKPPAHYTEGTLLDAMKNAARFVTDPRLKQRLRETEGLGTEATRAGLIQGLIDKG  539

Query  537  YLVKKGRSIRASDAAFTLIDAVPAAIADPGTTAVWEQALDMIEAGQLTLDVFIGKQAAWI  596
            +L+KK +S+ AS  A +LID++P  + +PG TA+WEQAL+ I  G +TLD F+ KQ A +
Sbjct  540  FLLKKKKSLVASAEAVALIDSLPDLLKNPGLTALWEQALNQIAEGSMTLDAFMQKQEAFV  599

Query  597  SQLIVQYGSTSLSIKVPQGPACPQCGAPTRQRTGKTGPFWSCSRYPDCKGTLPVDSGTSK  656
             QLI      ++S+   +   C++CG P R+     G FW+C+ YPDC+     +  + K
Sbjct  600  KQLIGSCMQQGMSLGNIEIRKCSECGKPMRKINHAKGTFWGCTGYPDCQ-----HKEADK  654

Query  657  RGASRPRSSGRKGS  670
            +  S +  S++K+S
Sbjct  655  KVKSASNKSAKKSS  668

> NC_016808_R1|63|G56|378773985|YP_005176228.1|Pasteurella_multocida_36950|-|54272..56323|topB1|Pmu_03290|DNA 
topoisomerase 
III
Length=683

 Score =  581 bits (2195),  Expect = 4e-167, Method: Compositional matrix adjust.
 Identities = 326/669 (49%), Positives = 485/669 (73%), Gaps = 8/669 (1%)

Query  1    MCEKPSQGKDIGRVLGATQRGNGCLAGS--GITVTWCIGHLVEAAPPETYGEQYKRWSIE  58
            +CEKPSQ++D++ VLGAT +G+G LA +  +I VTW +GHLVE   PE Y+E  KRW++E
Sbjct  5    ICEKPSQARDLAGVLGATSKGEGLLATADKSIIVTWGFGHLVEQYQPEDYDEAWKRWAFE  64

Query  59   QLPIIPERWRVEVKSKTASQFNVVKNLLSKATELVIATDADREGELIAREIIELCGYHGP  118
             LPIIP +W++  K  +  Q++VV  L+ KAT +VIATDADREGE+IARE+++L GY+G 
Sbjct  65   TLPIIPAQWKMTPKKESKKQYSVVIGLIKKATSVVIATDADREGEMIARELLDLAGYRGQ  124

Query  119  IQRLWLSALNDASIRKALAALRPSGETLPMYFSALARSRADWLIGMNLSRLFTVMGRQAG  178
            IQR WLSAL+DASIRKAL +L+++ ET ++Y+++++RSR+DWLIGMN+SRLFT+M++  G
Sbjct  125  IQRCWLSALDDASIRKALQTLKSGKETEALYYAGMGRSRSDWLIGMNFSRLFTLMAQAKG  184

Query  179  YDG-VLSVGRVQTPTLKLVVDRDREIARFVSVPFWTVETVLSSA-GQSFTAGWLAPDTAT  236
            Y G  LSVGRVQ+PTL LVV+RDREIA FV+ +  ++   L+++ G++F AG   P+   
Sbjct  185  YSGKPLSVGRVQSPTLTLVVNRDREIANFVPKSHYALAVQLTTTSGETFVAGLAVPEQYL  244

Query  237  DDAGRCLQEPIARQAAERMRIAGSAQVTSVETERLREGPPLPFDLGTLQEICSKQLGLDV  296
            D++G CL+  + +QA  +++ +G A+V +VET R + +PPL + L+ LQ  C++ +G++ 
Sbjct  245  DESGLCLDSRVIQQAEAQIKQTGLAKVVTVETKREKKSPPLLYALSDLQGECNRLFGFGA  304

Query  297  QETLEIAQALYETHKATTYPRSDSGYLPESMFAEVPVVLDSLLKTDPGLRPIVDQLDRNQ  356
            Q+ L+IAQ+LYE HK TTYPR+D GYLPES F++VP V+ SL+ +D+GL+ ++ +L+  Q
Sbjct  305  QQVLDIAQSLYEEHKITTYPRTDCGYLPESQFSDVPNVIRSLVASDSGLQTLLPKLNLRQ  364

Query  357  RSRAWNDSKVTAHHGIIPTLEPANLTAMSDKEQAVYKLIRAHYLAQFLPQHEFDRTTACL  416
            +SRAW+D K+TAHHGIIPT+  A+L+ +S+ E  VY LIR +YLAQFLP+ E D+T A L
Sbjct  365  KSRAWDDKKITAHHGIIPTIKKADLSKLSEEEMKVYDLIRRRYLAQFLPHLEMDKTVATL  424

Query  417  SCTGETLQAVGKQIVVIGWRQVLTEPRPDEDGETTLRSQVLPALHEGLSCQITGIDCKAL  476
              +G+TL A G+ IV  GWR +L     DE+       Q LP L     C++T  + ++L
Sbjct  425  QSSGHTLVARGNVIVAQGWR-ILFGKNVDEETGNDDEKQGLPVLTKNQQCNVTHSEVRTL  483

Query  477  KTSPPRPYTQGELVKAMKGVAKLVSDPRLKQKLKDTTGIGTEATRANIIKGLLDRGYLLK  536
            +T PP  YT+G L+ AMK  A++V+DPRLKQ+L++T G+GTEATRA +I+GL+D+G+LLK
Sbjct  484  QTKPPAHYTEGTLLDAMKNAARFVTDPRLKQRLRETEGLGTEATRAGLIQGLIDKGFLLK  543

Query  537  KSRSVRASDAAFTLIDAVPGAIADPGMTAIWEQALDMIEAGQLTLDVFIDKQSAWITQLV  596
            K +S+ AS  A +LID++P+ + +PG+TA+WEQAL+ I  G +TLD F++KQ A + QL+
Sbjct  544  KKKSLVASAEAVALIDSLPDLLKNPGLTALWEQALNQIAEGSMTLDAFMQKQEAFVKQLI  603

Query  597  QQYRGASLSIKVPQGPACPECGTAMRQRTGKSGPFWSCPRYPDCKGSQPIDSGKHKRAMP  656
                  ++S+   +   C+ECG +MR+     G FW+C  YPDC   Q  +++K  ++ +
Sbjct  604  GSCMQQGMSLGNIEIRKCSECGKPMRKINHAKGTFWGCTGYPDC---QHKEADKKVKSAS  660

Query  657  RKRSRSSRE  665
             K ++ S +
Sbjct  661  NKSAKKSSN  669

> NC_016808_R1|63|G56|378773985|YP_005176228.1|Pasteurella_multocida_36950|-|54272..56323|topB1|Pmu_03290|DNA 
topoisomerase 
III
Length=683

 Score =  580 bits (2189),  Expect = 1e-166, Method: Compositional matrix adjust.
 Identities = 331/651 (51%), Positives = 481/651 (74%), Gaps = 9/651 (1%)

Query  1    MRLFLCEKPSQGKDIGRILGATQRGEGCLNGS--GVTITWCIGHLVEAAAPEVYDAALKR  58
            M+LF+CEKPSQ++D++ +LGAT +GEG L  +  ++ +TW +GHLVE   PE YD A KR
Sbjct  1    MKLFICEKPSQARDLAGVLGATSKGEGLLATADKSIIVTWGFGHLVEQYQPEDYDEAWKR  60

Query  59   WSLEQLPIIPQQWRVEVKPKTATQFKVVKALLAKATHLVIATDADREGELIAREIIDLCG  118
            W++E LPIIP QW++  K  +  Q+ VV +L+ KAT +VIATDADREGE+IARE++DL G
Sbjct  61   WAFETLPIIPAQWKMTPKKESKKQYSVVIGLIKKATSVVIATDADREGEMIARELLDLAG  120

Query  119  YRGPIERLWLSALNDASIRTALGKLRPSSDTLPMYYSALARSRADWLVGMNLSRLFTLLG  178
            YRG I+R WLSAL+DASIR AL  L+++ +T ++YY++++RSR+DWL+GMN+SRLFTL++
Sbjct  121  YRGQIQRCWLSALDDASIRKALQTLKSGKETEALYYAGMGRSRSDWLIGMNFSRLFTLMA  180

Query  179  RQAGYDG-VLSVGRVQTPTLKLVVDRDREIAAFKSVPFWAIDVSLSA-EGQAFAAQWVAP  236
            +  GY G  LSVGRVQ+PTL LVV+RDREIA F + +  A+ V L++  G++F A    P
Sbjct  181  QAKGYSGKPLSVGRVQSPTLTLVVNRDREIANFVPKSHYALAVQLTTTSGETFVAGLAVP  240

Query  237  DDCTDDAGRCLqqpvaqqaaqqiraagsaqVVSVGTERVREGPPLLFDLSTLQEVCSRQV  296
            ++  D++G CL+  V QQA  QI+ +G A+VV+V T R + +PPLL+ LS LQ  C+R  
Sbjct  241  EQYLDESGLCLDSRVIQQAEAQIKQTGLAKVVTVETKREKKSPPLLYALSDLQGECNRLF  300

Query  297  GLDVQETLQIAQALYETHKATTYPRSDSGYLPESMFAEVPIVLDSLLNTDPSLRPIMGQL  356
            G++ Q+ L+IAQ+LYE HK TTYPR+D GYLPES F++VP V+ SL+ +D++L+ ++ +L
Sbjct  301  GFGAQQVLDIAQSLYEEHKITTYPRTDCGYLPESQFSDVPNVIRSLVASDSGLQTLLPKL  360

Query  357  DRSQRSRAWNDGKVTAHHGIIPTLEPANLSALSEKELAVYRLIRAHYLAQFLPHHEFDRT  416
            +  Q+SRAW+D K+TAHHGIIPT+  A+LS LSE E+ VY LIR +YLAQFLPH E D+T
Sbjct  361  NLRQKSRAWDDKKITAHHGIIPTIKKADLSKLSEEEMKVYDLIRRRYLAQFLPHLEMDKT  420

Query  417  VAEFSCGQQTLVATGKQVVVKGWRLVLAEPQADEDGDDTARSQVLPPLREGLACQVAEVE  476
            VA +  + +TLVA G+ +V +GWR++++    +E G+D  + Q LP L     C+V++ E
Sbjct  421  VATLQSSGHTLVARGNVIVAQGWRILFGKNVDEETGNDDEK-QGLPVLTKNQQCNVTHSE  479

Query  477  IKALKTMPAKPYTQGELVKSMKGIARFVTDPRLKQKLKDTTGIGTEATRANIISVLIARG  536
            +++L+T P+  YT+G L+ +MK  ARFVTDPRLKQ+L++T G+GTEATRA +I  LI +G
Sbjct  480  VRTLQTKPPAHYTEGTLLDAMKNAARFVTDPRLKQRLRETEGLGTEATRAGLIQGLIDKG  539

Query  537  YIVKKGRSIRASDAAFTLIDAVPAAIADPGTTAVWEQALDMIEAGQLTLDVFLSKQAAWI  596
            +++KK +S+ AS  A +LID++P  + +PG TA+WEQAL+ I  G +TLD F+ KQ A +
Sbjct  540  FLLKKKKSLVASAEAVALIDSLPDLLKNPGLTALWEQALNQIAEGSMTLDAFMQKQEAFV  599

Query  597  SQLIAQYGCVSLSIKLSHGPA--CPQCGAATRQRTGKSGPFWSCSRYPDCK  645
             QLI+  +C+  ++ L++     C++CG + R+     G FW+C+ YPDC+
Sbjct  600  KQLIG--SCMQQGMSLGNIEIRKCSECGKPMRKINHAKGTFWGCTGYPDCQ  648

> NC_016808_R1|63|G56|378773985|YP_005176228.1|Pasteurella_multocida_36950|-|54272..56323|topB1|Pmu_03290|DNA 
topoisomerase 
III
Length=683

 Score =  578 bits (2181),  Expect = 6e-166, Method: Compositional matrix adjust.
 Identities = 338/670 (51%), Positives = 487/670 (73%), Gaps = 11/670 (1%)

Query  1    MKLFLCEKPSQGRDIAAVLGATKKMPG--HQTGNGVCVTWGFGHLLEQASPDAYGEQFGV  58
            MKLF+CEKPSQ+RD+A+VLGAT K  G    +++++ VTWGFGHL+EQ  P+ Y+E    
Sbjct  1    MKLFICEKPSQARDLAGVLGATSKGEGLLATADKSIIVTWGFGHLVEQYQPEDYDEAWK-  59

Query  59   PWRTDVLPVLPTMWQMRVKPDAAAQFSVIQKLLKQADTVVIATDADREGEVIAREILDYC  118
             W  + LP++P+ W+M  K ++  Q+SV+  L+K+A +VVIATDADREGE+IARE+LD  
Sbjct  60   RWAFETLPIIPAQWKMTPKKESKKQYSVVIGLIKKATSVVIATDADREGEMIARELLDLA  119

Query  119  HYQGKVERLWLSALDEASVRAALATIKPGSTTLPYYLAGLGRARADWQIGMNMTRLYSVK  178
             Y+G+++R WLSALD+AS+R AL T+K+G  T + Y AG+GR+R+DW IGMN +RL+++ 
Sbjct  120  GYRGQIQRCWLSALDDASIRKALQTLKSGKETEALYYAGMGRSRSDWLIGMNFSRLFTLM  179

Query  179  ARENGY-GSVLSVGRVQTPTLNLIVVRDRDIVQFVPKPYWNVVAQLAA-GGIAFQAQWVP  236
            A+ +GY G  LSVGRVQ+PTL L+V RDR+I +FVPK+   +  QL++ +G +F A    
Sbjct  180  AQAKGYSGKPLSVGRVQSPTLTLVVNRDREIANFVPKSHYALAVQLTTTSGETFVAGLAV  239

Query  237  AEAYCDEEKRCINPTAAQQVVQLCQKTGQATVAEVETKRETESAPLAFDLGTLQQACSRR  296
            +E Y DE   C+++   QQ     ++TG A V  VETKRE  S+PL + L+ LQ  C+R 
Sbjct  240  PEQYLDESGLCLDSRVIQQAEAQIKQTGLAKVVTVETKREKKSPPLLYALSDLQGECNRL  299

Query  297  FGYGAQQVLDIAQALYETYKATTYPRTDCGYLPTSMRGEIGQVMSSIQQSDPALSAIISR  356
            FG+GAQQVLDIAQ+LYE  K TTYPRTDCGYLP S  +++ +V+ S+  SD++L +++++
Sbjct  300  FGFGAQQVLDIAQSLYEEHKITTYPRTDCGYLPESQFSDVPNVIRSLVASDSGLQTLLPK  359

Query  357  LDMKHVSRIWNDKKITAHHGIIPTKQPCDLAKMSEQERNVYQLIRLHYLAQFLPNHEVDA  416
            L++++ SR W+DKKITAHHGIIPT +  DL+K+SE+E +VY+LIR +YLAQFLP+ E+D 
Sbjct  360  LNLRQKSRAWDDKKITAHHGIIPTIKKADLSKLSEEEMKVYDLIRRRYLAQFLPHLEMDK  419

Query  417  TRVSLHCGGQLFKTSGKAVVVAGWKSLFgkdadedagdagdkaRLPAMAKGSLCQVTGAE  476
            T  +L+ +G+ + + G+ +V  GW+ LFGK+ DE++G+ ++K  LP ++K   C+VT +E
Sbjct  420  TVATLQSSGHTLVARGNVIVAQGWRILFGKNVDEETGNDDEKQGLPVLTKNQQCNVTHSE  479

Query  477  AKPQQTKPPEHYTEGTLIAAMKNAAQFVTDPRLKKILKENAGLGTEATRAGVIETLLKRG  536
             +  QTKPP HYTEGTL+ AMKNAA+FVTDPRLK+ L+E  GLGTEATRAG+I+ L+ +G
Sbjct  480  VRTLQTKPPAHYTEGTLLDAMKNAARFVTDPRLKQRLRETEGLGTEATRAGLIQGLIDKG  539

Query  537  FVVKKGKHLLATPIAADLMAVLPAQLKDPGMTALWEQSLDDIAEGRMSLDDFMAKQSAWT  596
            F++KK K L+A++ A  L+  LP  LK+PG+TALWEQ+L++IAEG M+LD FM KQ A  
Sbjct  540  FLLKKKKSLVASAEAVALIDSLPDLLKNPGLTALWEQALNQIAEGSMTLDAFMQKQEAFV  599

Query  597  MQLVAKGQHQTVKITLPPSPPCPICGGVTRQRTGKSGSFWGCVNYPDCNGIVNVGAKKPG  656
             QL++   +Q + +       C+ CG   R+     G+FWGC  YPDC+       K ++
Sbjct  600  KQLIGSCMQQGMSLGNIEIRKCSECGKPMRKINHAKGTFWGCTGYPDCQ------HKEAD  653

Query  657  RRRKSPAKKS  666
            ++ KS+++KS
Sbjct  654  KKVKSASNKS  663

> NC_016808_R1|63|G56|378773985|YP_005176228.1|Pasteurella_multocida_36950|-|54272..56323|topB1|Pmu_03290|DNA 
topoisomerase 
III
Length=683

 Score =  578 bits (2181),  Expect = 6e-166, Method: Compositional matrix adjust.
 Identities = 338/670 (51%), Positives = 487/670 (73%), Gaps = 11/670 (1%)

Query  1    MKLFLCEKPSQGRDIAAVLGATKKMPG--HQTGNGVCVTWGFGHLLEQASPDAYGEQFGV  58
            MKLF+CEKPSQ+RD+A+VLGAT K  G    +++++ VTWGFGHL+EQ  P+ Y+E    
Sbjct  1    MKLFICEKPSQARDLAGVLGATSKGEGLLATADKSIIVTWGFGHLVEQYQPEDYDEAWK-  59

Query  59   PWRTDVLPVLPTMWQMRVKPDAAAQFSVIQKLLKQADTVVIATDADREGEVIAREILDYC  118
             W  + LP++P+ W+M  K ++  Q+SV+  L+K+A +VVIATDADREGE+IARE+LD  
Sbjct  60   RWAFETLPIIPAQWKMTPKKESKKQYSVVIGLIKKATSVVIATDADREGEMIARELLDLA  119

Query  119  HYQGKVERLWLSALDEASVRAALATIKPGSTTLPYYLAGLGRARADWQIGMNMTRLYSVK  178
             Y+G+++R WLSALD+AS+R AL T+K+G  T + Y AG+GR+R+DW IGMN +RL+++ 
Sbjct  120  GYRGQIQRCWLSALDDASIRKALQTLKSGKETEALYYAGMGRSRSDWLIGMNFSRLFTLM  179

Query  179  ARENGY-GSVLSVGRVQTPTLNLIVVRDRDIVQFVPKPYWNVVAQLAA-GGIAFQAQWVP  236
            A+ +GY G  LSVGRVQ+PTL L+V RDR+I +FVPK+   +  QL++ +G +F A    
Sbjct  180  AQAKGYSGKPLSVGRVQSPTLTLVVNRDREIANFVPKSHYALAVQLTTTSGETFVAGLAV  239

Query  237  AEAYCDEEKRCINPTAAQQVVQLCQKTGQATVAEVETKRETESAPLAFDLGTLQQACSRR  296
            +E Y DE   C+++   QQ     ++TG A V  VETKRE  S+PL + L+ LQ  C+R 
Sbjct  240  PEQYLDESGLCLDSRVIQQAEAQIKQTGLAKVVTVETKREKKSPPLLYALSDLQGECNRL  299

Query  297  FGYGAQQVLDIAQALYETYKATTYPRTDCGYLPTSMRGEIGQVMSSIQQSDPALSAIISR  356
            FG+GAQQVLDIAQ+LYE  K TTYPRTDCGYLP S  +++ +V+ S+  SD++L +++++
Sbjct  300  FGFGAQQVLDIAQSLYEEHKITTYPRTDCGYLPESQFSDVPNVIRSLVASDSGLQTLLPK  359

Query  357  LDMKHVSRIWNDKKITAHHGIIPTKQPCDLAKMSEQERNVYQLIRLHYLAQFLPNHEVDA  416
            L++++ SR W+DKKITAHHGIIPT +  DL+K+SE+E +VY+LIR +YLAQFLP+ E+D 
Sbjct  360  LNLRQKSRAWDDKKITAHHGIIPTIKKADLSKLSEEEMKVYDLIRRRYLAQFLPHLEMDK  419

Query  417  TRVSLHCGGQLFKTSGKAVVVAGWKSLFgkdadedagdagdkaRLPAMAKGSLCQVTGAE  476
            T  +L+ +G+ + + G+ +V  GW+ LFGK+ DE++G+ ++K  LP ++K   C+VT +E
Sbjct  420  TVATLQSSGHTLVARGNVIVAQGWRILFGKNVDEETGNDDEKQGLPVLTKNQQCNVTHSE  479

Query  477  AKPQQTKPPEHYTEGTLIAAMKNAAQFVTDPRLKKILKENAGLGTEATRAGVIETLLKRG  536
             +  QTKPP HYTEGTL+ AMKNAA+FVTDPRLK+ L+E  GLGTEATRAG+I+ L+ +G
Sbjct  480  VRTLQTKPPAHYTEGTLLDAMKNAARFVTDPRLKQRLRETEGLGTEATRAGLIQGLIDKG  539

Query  537  FVVKKGKHLLATPIAADLMAVLPAQLKDPGMTALWEQSLDDIAEGRMSLDDFMAKQSAWT  596
            F++KK K L+A++ A  L+  LP  LK+PG+TALWEQ+L++IAEG M+LD FM KQ A  
Sbjct  540  FLLKKKKSLVASAEAVALIDSLPDLLKNPGLTALWEQALNQIAEGSMTLDAFMQKQEAFV  599

Query  597  MQLVAKGQHQTVKITLPPSPPCPICGGVTRQRTGKSGSFWGCVNYPDCNGIVNVGAKKPG  656
             QL++   +Q + +       C+ CG   R+     G+FWGC  YPDC+       K ++
Sbjct  600  KQLIGSCMQQGMSLGNIEIRKCSECGKPMRKINHAKGTFWGCTGYPDCQ------HKEAD  653

Query  657  RRRKSPAKKS  666
            ++ KS+++KS
Sbjct  654  KKVKSASNKS  663

> NC_016808_R1|63|G56|378773985|YP_005176228.1|Pasteurella_multocida_36950|-|54272..56323|topB1|Pmu_03290|DNA 
topoisomerase 
III
Length=683

 Score =  577 bits (2180),  Expect = 7e-166, Method: Compositional matrix adjust.
 Identities = 328/677 (49%), Positives = 488/677 (73%), Gaps = 13/677 (1%)

Query  1    MRLFLCEKPSQGKDIGRVLGTTQRGNGCLTGS--GITVTWCIGHLVEAAPPETYGEQYKR  58
            M+LF+CEKPSQ++D++ VLG+T +G+G L+ +  +I VTW +GHLVE   PE Y+E  KR
Sbjct  1    MKLFICEKPSQARDLAGVLGATSKGEGLLATADKSIIVTWGFGHLVEQYQPEDYDEAWKR  60

Query  59   WSIEQLPIIPECWRVEVKSKTASQFNVVKELLSKATELVIATDADREGELIAREIIELCG  118
            W++E LPIIP  W++  K  +  Q++VV  L+ KAT +VIATDADREGE+IARE+++L G
Sbjct  61   WAFETLPIIPAQWKMTPKKESKKQYSVVIGLIKKATSVVIATDADREGEMIARELLDLAG  120

Query  119  YRGPIQRLWLSALNDTSIRKALSVLRPSDETLPMYFSALARSRADWLIGMNLSRLFTVLG  178
            YRG IQR WLSAL+D+SIRKAL  L+++ ET ++Y+++++RSR+DWLIGMN+SRLFT+++
Sbjct  121  YRGQIQRCWLSALDDASIRKALQTLKSGKETEALYYAGMGRSRSDWLIGMNFSRLFTLMA  180

Query  179  RQAGYDG-VLSVGRVQTPTLKLVVDRDREIARFVSVPFWAVEVVLSSA-GQHFTAAWLAP  236
            +  GY G  LSVGRVQ+PTL LVV+RDREIA FV+ +  A+ V L+++ G+ F A+   P
Sbjct  181  QAKGYSGKPLSVGRVQSPTLTLVVNRDREIANFVPKSHYALAVQLTTTSGETFVAGLAVP  240

Query  237  DTAADNAGRCLQEPIARQATERMRVTGSAQVTSVETEHMREGPPLPFDLGTLQEVCSRQL  296
            +   D++G CL+  + +QA  +++ TG A+V +VET + + +PPL + L+ LQ  C+R +
Sbjct  241  EQYLDESGLCLDSRVIQQAEAQIKQTGLAKVVTVETKREKKSPPLLYALSDLQGECNRLF  300

Query  297  GLDVQETLEIAQALYETHKATTYPRSDSGYLPESMFAEVPIVFDSLLKTDPDLRPIVDLL  356
            G++ Q+ L+IAQ+LYE HK TTYPR+D GYLPES F++VP V+ SL+ +D++L+ ++  L
Sbjct  301  GFGAQQVLDIAQSLYEEHKITTYPRTDCGYLPESQFSDVPNVIRSLVASDSGLQTLLPKL  360

Query  357  DRNQRSRAWNDSKVTAHHGIIPTLEPANLAAMSDKERAVYTLIRTHYLAQFLPHHEFDHT  416
            +  Q+SRAW+D K+TAHHGIIPT+  A+L+ +S+ E  VY LIR +YLAQFLPH E D T
Sbjct  361  NLRQKSRAWDDKKITAHHGIIPTIKKADLSKLSEEEMKVYDLIRRRYLAQFLPHLEMDKT  420

Query  417  TAYLSCAGEMLQAVGKQVVLVGWRRVLTEPKPDDDGDTTSRSQVLPPLNEGLSCQITGID  476
             A L  +G+ L A G+ +V  GW R+L   + D++ +     Q LP L     C++T  +
Sbjct  421  VATLQSSGHTLVARGNVIVAQGW-RILFGKNVDEETGNDDEKQGLPVLTKNQQCNVTHSE  479

Query  477  CKALKTSPPRPYTQGELVKSMKSVAKLVSDPRLKQTLKDTTGIGTEATRANIIKGLLDRG  536
             ++L+T PP  YT+G L+ +MK+ A++V+DPRLKQ L++T G+GTEATRA +I+GL+D+G
Sbjct  480  VRTLQTKPPAHYTEGTLLDAMKNAARFVTDPRLKQRLRETEGLGTEATRAGLIQGLIDKG  539

Query  537  YLLKKGRSVRASDAAFTLIDAVPGAIADPGMTAIWEQALDMIESGQLTLDVFIDKQSAWI  596
            +LLKK +S+ AS  A +LID++P+ + +PG+TA+WEQAL+ I  G +TLD F++KQ A +
Sbjct  540  FLLKKKKSLVASAEAVALIDSLPDLLKNPGLTALWEQALNQIAEGSMTLDAFMQKQEAFV  599

Query  597  AQLIQQYRGASLSIQMPLGPA----CPECGTPMHQRPGKNGAFWSCPRYPDCRGSLPIDS  652
             QLI    G+ +   M+LG      C+ECG PM++    +G+FW+C  YPDC+   +   
Sbjct  600  KQLI----GSCMQQGMSLGNIEIRKCSECGKPMRKINHAKGTFWGCTGYPDCQHKEADKK  655

Query  653  GKRKRTTPRKRNSSLQA  669
             K     + K++S+L+ 
Sbjct  656  VKSASNKSAKKSSNLNV  672

> NC_016808_R1|63|G56|378773985|YP_005176228.1|Pasteurella_multocida_36950|-|54272..56323|topB1|Pmu_03290|DNA 
topoisomerase 
III
Length=683

 Score =  576 bits (2176),  Expect = 1e-165, Method: Compositional matrix adjust.
 Identities = 322/650 (50%), Positives = 479/650 (74%), Gaps = 6/650 (0%)

Query  1    MRVFLCEKPSQGKDIARVLGARQRGNG--CYSGSGITVTWCIGHLVEAAPPETYGEQYKQ  58
            M++F+CEKPSQ++D+A VLGA  +G+G    ++ +I VTW +GHLVE   PE Y+E  K+
Sbjct  1    MKLFICEKPSQARDLAGVLGATSKGEGLLATADKSIIVTWGFGHLVEQYQPEDYDEAWKR  60

Query  59   WSIEQLPILPERWRIEVKAKTAAQFKIVKQFVAQAGELVIATDADREGEMIAREIIDLCG  118
            W++E LPI+P +W++  K  +  Q+ +V  ++ +A  +VIATDADREGEMIARE++DL G
Sbjct  61   WAFETLPIIPAQWKMTPKKESKKQYSVVIGLIKKATSVVIATDADREGEMIARELLDLAG  120

Query  119  YRGPIQRLWLSALNDASIRKALTQLKPGGETLPLYFSALARSRADWLIGMNLSRLFTVLG  178
            YRG IQR WLSAL+DASIRKAL  LK+G ET +LY+++++RSR+DWLIGMN+SRLFT+++
Sbjct  121  YRGQIQRCWLSALDDASIRKALQTLKSGKETEALYYAGMGRSRSDWLIGMNFSRLFTLMA  180

Query  179  RRSGYQG-VLSVGRVQTPTLKLVVDRDREIARFVSVPYWTIDVTLSHA-GQSFAASWMPP  236
            +  GY G  LSVGRVQ+PTL LVV+RDREIA FV+ +  ++ V L+ + G++F A+   P
Sbjct  181  QAKGYSGKPLSVGRVQSPTLTLVVNRDREIANFVPKSHYALAVQLTTTSGETFVAGLAVP  240

Query  237  DGTTDAAGRCLQQPVAQQAADRIRAGRESKVLSVETERVREAAPLPFDLGTLQEVCSRQL  296
            +   D +G CL+  V QQA  +I+    +KV++VET R + ++PL + L+ LQ  C+R +
Sbjct  241  EQYLDESGLCLDSRVIQQAEAQIKQTGLAKVVTVETKREKKSPPLLYALSDLQGECNRLF  300

Query  297  GLDVQETLDIAQSLYETHKATTYPRSDSGYLPESMLAEVPTVLDALLATDPGLRPLIDRL  356
            G++ Q+ LDIAQSLYE HK TTYPR+D GYLPES +++VP V+ +L+A+D+GL+ L+ +L
Sbjct  301  GFGAQQVLDIAQSLYEEHKITTYPRTDCGYLPESQFSDVPNVIRSLVASDSGLQTLLPKL  360

Query  357  DRTQRSRVWNDSKITAHHGIIPTLEPANLSAMSEKELAVYALIRAHYLAQFLPHHEFDRT  416
            +  Q+SR W+D KITAHHGIIPT+  A+LS +SE E+ VY LIR +YLAQFLPH E D+T
Sbjct  361  NLRQKSRAWDDKKITAHHGIIPTIKKADLSKLSEEEMKVYDLIRRRYLAQFLPHLEMDKT  420

Query  417  LVMLDCAGQSLQAVGKRVIVPGWHLALPGKGQDAADDEPAQRSQILPPLDTGARCGVQQV  476
            +  L+ +G++L A G+ ++  GW++ +  + ++ ++++  +++  LP L    +C V + 
Sbjct  421  VATLQSSGHTLVARGNVIVAQGWRILFGKNVDEETGNDDEKQG--LPVLTKNQQCNVTHS  478

Query  477  ELKALKTLPPKPYTQGELIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRAGIINGLLAR  536
            E+++L+T PP  YT+G L+ AMK  A++VTDPRLKQ+L+ET G+GTEATRAG+I+GL+ +
Sbjct  479  EVRTLQTKPPAHYTEGTLLDAMKNAARFVTDPRLKQRLRETEGLGTEATRAGLIQGLIDK  538

Query  537  GYLVKKGRAIRASDAAFTLIDAVPAAITDPGTTAIWEQALDMIEAGQMTLDTFINKQSAW  596
            G+L+KK +++ AS  A +LID++P  + +PG TA+WEQAL+ I  G MTLD+F++KQ A 
Sbjct  539  GFLLKKKKSLVASAEAVALIDSLPDLLKNPGLTALWEQALNQIAEGSMTLDAFMQKQEAF  598

Query  597  VAQLVQQYRGTVLSIKLPEGPACPVCGAATRQRNGKNGAFWSCSRYPDCK  646
            V QL+       +S+   E   C+ CG + R+ N  +G+FW+C+ YPDC+
Sbjct  599  VKQLIGSCMQQGMSLGNIEIRKCSECGKPMRKINHAKGTFWGCTGYPDCQ  648

> NC_016808_R1|63|G56|378773985|YP_005176228.1|Pasteurella_multocida_36950|-|54272..56323|topB1|Pmu_03290|DNA 
topoisomerase 
III
Length=683

 Score =  576 bits (2175),  Expect = 2e-165, Method: Compositional matrix adjust.
 Identities = 328/650 (51%), Positives = 480/650 (74%), Gaps = 6/650 (0%)

Query  1    MRVFLCEKPSQGKDIARVLGAGQRGNG--CYSGAGVVVTWCIGHLVEAVPPEGYGEQYKR  58
            M++F+CEKPSQ++D+A VLGA  +G+G    ++ +++VTW +GHLVE   PE+Y+E  KR
Sbjct  1    MKLFICEKPSQARDLAGVLGATSKGEGLLATADKSIIVTWGFGHLVEQYQPEDYDEAWKR  60

Query  59   WAIEQLPILPERWRVEPKAATAAQFKVVQQLVAKAGELVIATDADREGEMIAREIIDLCG  118
            WA+E LPI+P +W++ PK  +  Q+ VV  L+ KA  +VIATDADREGEMIARE++DL G
Sbjct  61   WAFETLPIIPAQWKMTPKKESKKQYSVVIGLIKKATSVVIATDADREGEMIARELLDLAG  120

Query  119  YRGPIQRLWLSALNDASIRKALGALKPSAETLPLYFSALARSRADWLIGMNLSRLFTLLG  178
            YRG IQR WLSAL+DASIRKAL +LK++ ET +LY+++++RSR+DWLIGMN+SRLFTL++
Sbjct  121  YRGQIQRCWLSALDDASIRKALQTLKSGKETEALYYAGMGRSRSDWLIGMNFSRLFTLMA  180

Query  179  RQAGYSG-VLSVGRVQTPTLKLVVDRDREIARFVCVPFWAIEVALSHA-GQPFVASWTPP  236
            +  GYSG  LSVGRVQ+PTL LVV+RDREIA FV  +  A+ V L+ + G+ FVA+ + P
Sbjct  181  QAKGYSGKPLSVGRVQSPTLTLVVNRDREIANFVPKSHYALAVQLTTTSGETFVAGLAVP  240

Query  237  QGSTDDAGRCLQQPvaqqaadriraardaqvvSVDTERVREAPPLPFDLGTLQEVCSKQL  296
            +   D++G CL+  V QQA  +I+ +  A+VV+V+T R + +PPL + L+ LQ  C++ +
Sbjct  241  EQYLDESGLCLDSRVIQQAEAQIKQTGLAKVVTVETKREKKSPPLLYALSDLQGECNRLF  300

Query  297  GLDVQETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLDALLATDPSLRPLIGQL  356
            G++ Q+ LDIAQ+LYE HK TTYPR+D GYLPES +++VP V+ +L+A+D++L+ L+ +L
Sbjct  301  GFGAQQVLDIAQSLYEEHKITTYPRTDCGYLPESQFSDVPNVIRSLVASDSGLQTLLPKL  360

Query  357  DRNQRSRAWNDGKVSAHHGIIPTLEPANLSAMNEKELAVYRLIRAHYLAQFLPHHEFDRT  416
            +  Q+SRAW+D K++AHHGIIPT+  A+LS ++E E+ VY LIR +YLAQFLPH E D+T
Sbjct  361  NLRQKSRAWDDKKITAHHGIIPTIKKADLSKLSEEEMKVYDLIRRRYLAQFLPHLEMDKT  420

Query  417  VAQFSCGSQSLAAVGKQIAVTGWREVLATPGPDDADGEDALRSQVLPALHAGLSCPVGKV  476
            VA +  ++++L A G+ I   GWR +++    ++++ +D    Q LP L     C V   
Sbjct  421  VATLQSSGHTLVARGNVIVAQGWRILFGKNVDEETGNDDE--KQGLPVLTKNQQCNVTHS  478

Query  477  DLKALRTLPPKPYTQGELIKAMKTVAKFVTDPRLKQKLRDTTGIGTEATRANIINGLIGR  536
            ++++L+T PP  YT+G L+ AMK  A+FVTDPRLKQ+LR+T G+GTEATRA +I+GLI++
Sbjct  479  EVRTLQTKPPAHYTEGTLLDAMKNAARFVTDPRLKQRLRETEGLGTEATRAGLIQGLIDK  538

Query  537  GYLVKKGRAVRASDAAFTLIDAVPSAIADPGTTAVWEQALDMIEAGQMALDTFIEKQSVW  596
            G+L+KK +++ AS  A +LID++P  + +PG TA+WEQAL+ I  G M+LD+F++KQ   
Sbjct  539  GFLLKKKKSLVASAEAVALIDSLPDLLKNPGLTALWEQALNQIAEGSMTLDAFMQKQEAF  598

Query  597  VGQLVQQYRGATLSLKLPPTPACPQCGAPMQQRTGKSGAFWSCSRYPDCR  646
            V QL+       +SL       C++CG PM++     G+FW+C+ YPDC+
Sbjct  599  VKQLIGSCMQQGMSLGNIEIRKCSECGKPMRKINHAKGTFWGCTGYPDCQ  648

> NC_016808_R1|63|G56|378773985|YP_005176228.1|Pasteurella_multocida_36950|-|54272..56323|topB1|Pmu_03290|DNA 
topoisomerase 
III
Length=683

 Score =  574 bits (2169),  Expect = 5e-165, Method: Compositional matrix adjust.
 Identities = 322/650 (50%), Positives = 478/650 (74%), Gaps = 6/650 (0%)

Query  1    MRLFLCEKPSQGKDIGKVLGATQRDNGCLKGP--GVIVTWCIGHLVEAAPPEAYDANLKH  58
            M+LF+CEKPSQ++D++ VLGAT +++G L  +  ++IVTW +GHLVE   PE YD   K+
Sbjct  1    MKLFICEKPSQARDLAGVLGATSKGEGLLATADKSIIVTWGFGHLVEQYQPEDYDEAWKR  60

Query  59   WSIEQLPIIPERWRIEVKPKTAAQFKVVKQLLAQATELVIATDADREGEMIAREIVELCG  118
            W++E LPIIP +W++  K  +  Q+ VV  L+ +AT +VIATDADREGEMIARE+++L G
Sbjct  61   WAFETLPIIPAQWKMTPKKESKKQYSVVIGLIKKATSVVIATDADREGEMIARELLDLAG  120

Query  119  YRGPIQRLWLSALNDASIRKALAALKPSSETLPMYHSALARSRADWLVGMNLSRLFTLLG  178
            YRG IQR WLSAL+DASIRKAL +LK++ ET ++Y ++++RSR+DWL+GMN+SRLFTL++
Sbjct  121  YRGQIQRCWLSALDDASIRKALQTLKSGKETEALYYAGMGRSRSDWLIGMNFSRLFTLMA  180

Query  179  RQAGYDG-VLSVGRVQTPTLKLVVDRDREINQFVSIPFWAIDVALSAT-GQSFIAQWLAP  236
            +  GY G  LSVGRVQ+PTL LVV+RDREI +FV+ +  A+ V L++T G++F+A    P
Sbjct  181  QAKGYSGKPLSVGRVQSPTLTLVVNRDREIANFVPKSHYALAVQLTTTSGETFVAGLAVP  240

Query  237  EACTDEAGRCLQESVAQQAAQQLRANGTAQVASVETERVREGPPLPFDLGTLQEVCSKQL  296
            E   DE+G CL+  V QQA  Q++  G A+V +VET R + +PPL + L+ LQ  C++ +
Sbjct  241  EQYLDESGLCLDSRVIQQAEAQIKQTGLAKVVTVETKREKKSPPLLYALSDLQGECNRLF  300

Query  297  GLDVQETLDIAQALYETHKATTYPRSDSGYLPESMQADVPAVLDSLLRTDPALRPVMEQL  356
            G++ Q+ LDIAQ+LYE HK TTYPR+D GYLPES  +DVP V+ SL+ +D++L+ ++ +L
Sbjct  301  GFGAQQVLDIAQSLYEEHKITTYPRTDCGYLPESQFSDVPNVIRSLVASDSGLQTLLPKL  360

Query  357  DRRQRSRAWNDSKVTAHHGIIPTLEPANLSAMSEKELAVYRLIRAHYLAQFLPHHEFDRT  416
            + RQ+SRAW+D K+TAHHGIIPT+  A+LS +SE E+ VY LIR +YLAQFLPH E D+T
Sbjct  361  NLRQKSRAWDDKKITAHHGIIPTIKKADLSKLSEEEMKVYDLIRRRYLAQFLPHLEMDKT  420

Query  417  IARLSCAGQHLQAVGKQIVIPGWRLVLVeqqaedaddeaaPRSQVLPALNQGLSCQMNTV  476
            +A L  +G+ L A G+ IV  GWR+++  +  E+++++     Q LP L +   C++   
Sbjct  421  VATLQSSGHTLVARGNVIVAQGWRILFGKNVDEETGNDDE--KQGLPVLTKNQQCNVTHS  478

Query  477  DLKALKTLPPRPYTQGELVKAMKSVAKLVSDPRLKQKLKDTVGIGTEATRANIINGLLTR  536
            ++++L+T PP  YT+G L+ AMK+ A++V+DPRLKQ+L++T G+GTEATRA +I+GL+ +
Sbjct  479  EVRTLQTKPPAHYTEGTLLDAMKNAARFVTDPRLKQRLRETEGLGTEATRAGLIQGLIDK  538

Query  537  GYLIKKGRAIRASEAAGTLIDTVPAAIADPGTTAVWEQALDMIEAGELTHDVFTGKQSAW  596
            G+L+KK +++ AS  A +LID++P  + +PG TA+WEQAL+ I  G +T D F  KQ A 
Sbjct  539  GFLLKKKKSLVASAEAVALIDSLPDLLKNPGLTALWEQALNQIAEGSMTLDAFMQKQEAF  598

Query  597  ISQIIAQYQGTAMTIKVPQGPACPQCGSATRQRTGKNGPFWSCSRYPECK  646
            + Q+I+     +M++   +   C++CG + R+    +G FW+C+ YP+C+
Sbjct  599  VKQLIGSCMQQGMSLGNIEIRKCSECGKPMRKINHAKGTFWGCTGYPDCQ  648

> NC_016808_R1|63|G56|378773985|YP_005176228.1|Pasteurella_multocida_36950|-|54272..56323|topB1|Pmu_03290|DNA 
topoisomerase 
III
Length=683

 Score =  573 bits (2165),  Expect = 1e-164, Method: Compositional matrix adjust.
 Identities = 333/650 (52%), Positives = 481/650 (74%), Gaps = 6/650 (0%)

Query  1    MRVFLCEKPSQGKDIARVLGAGQRSNG--CYSGAGVVVTWCIGHLVEAVPPEGYGEQYKR  58
            M++F+CEKPSQ++D+A VLGA  +++G    ++ +++VTW +GHLVE   PE+Y+E  KR
Sbjct  1    MKLFICEKPSQARDLAGVLGATSKGEGLLATADKSIIVTWGFGHLVEQYQPEDYDEAWKR  60

Query  59   WAIEQLPIVPERWRVEPKVATAAQFKVVQQLVAKAGELVIATDADREGEMIAREIIDLCG  118
            WA+E LPI+P +W++ PK  +  Q+ VV  L+ KA  +VIATDADREGEMIARE++DL G
Sbjct  61   WAFETLPIIPAQWKMTPKKESKKQYSVVIGLIKKATSVVIATDADREGEMIARELLDLAG  120

Query  119  YRGPIQRLWLSALNDASIRKALGALKPSAETLPLYFSALARSRADWLIGMNLSRLFTLLG  178
            YRG IQR WLSAL+DASIRKAL +LK++ ET +LY+++++RSR+DWLIGMN+SRLFTL++
Sbjct  121  YRGQIQRCWLSALDDASIRKALQTLKSGKETEALYYAGMGRSRSDWLIGMNFSRLFTLMA  180

Query  179  RQAGYTG-VLSVGRVQTPTLKLVVDRDREIARFVSVPYWAADV-LLSHAGQSFTASWIPP  236
            +  GY+G  LSVGRVQ+PTL LVV+RDREIA FV+ +  A  V L + +G++F A+   P
Sbjct  181  QAKGYSGKPLSVGRVQSPTLTLVVNRDREIANFVPKSHYALAVQLTTTSGETFVAGLAVP  240

Query  237  EGSTDAAGRCLQQPVAQQAVDRIRAARDAQVVSVDTERVREAPPLPFDLGTLQEVCSRQL  296
            E   D +G CL+  V QQA  +I+ +  A+VV+V+T R + +PPL + L+ LQ  C+R +
Sbjct  241  EQYLDESGLCLDSRVIQQAEAQIKQTGLAKVVTVETKREKKSPPLLYALSDLQGECNRLF  300

Query  297  GLDVQETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLDALLATEPSLRPLLGQL  356
            G++ Q+ LDIAQ+LYE HK TTYPR+D GYLPES +++VP V+ +L+A++++L+ LL +L
Sbjct  301  GFGAQQVLDIAQSLYEEHKITTYPRTDCGYLPESQFSDVPNVIRSLVASDSGLQTLLPKL  360

Query  357  DRNQRSRAWNDGKVTAHHGIIPTLEPAKLLAMSEKELAVYQLIRGRYLAQFLPHHEFDRT  416
            +  Q+SRAW+D K+TAHHGIIPT+  A L  +SE E+ VY+LIR RYLAQFLPH E D+T
Sbjct  361  NLRQKSRAWDDKKITAHHGIIPTIKKADLSKLSEEEMKVYDLIRRRYLAQFLPHLEMDKT  420

Query  417  VTQLACGGQSLVAVGKQIAVIGWRQVLATPEPDAADGEEAQRSQVLPPLASGSRCGVEQV  476
            V+ L  +G++LVA G+ I   GWR +L   + D   G++ ++ Q LP L+   +C V + 
Sbjct  421  VATLQSSGHTLVARGNVIVAQGWR-ILFGKNVDEETGNDDEK-QGLPVLTKNQQCNVTHS  478

Query  477  ELKALRTLPPKPYTQGELVKVMKGVAKLVDDPRLKQKLKETTGIGTEATRASTIKGLLDR  536
            E+++L+T PP  YT+G L+  MK  A++V DPRLKQ+L+ET G+GTEATRA+ I+GL+D+
Sbjct  479  EVRTLQTKPPAHYTEGTLLDAMKNAARFVTDPRLKQRLRETEGLGTEATRAGLIQGLIDK  538

Query  537  GYLLKKGRAIRASDAAFTLIDAVPAAIADPGMTAIWEQALDMIEAGQMTLDTFIAKQSTW  596
            G+LLKK +++ AS  A +LID++P  + +PG+TA+WEQAL+ I  G MTLD+F+ KQ + 
Sbjct  539  GFLLKKKKSLVASAEAVALIDSLPDLLKNPGLTALWEQALNQIAEGSMTLDAFMQKQEAF  598

Query  597  VAQLVQQHRGATlsialppsppcpqcgapMRQRTGKSGAFWSCSRYPDCK  646
            V QL+       +S++      C++CG PMR+     G+FW+C+ YPDC+
Sbjct  599  VKQLIGSCMQQGMSLGNIEIRKCSECGKPMRKINHAKGTFWGCTGYPDCQ  648

> NC_016808_R1|63|G56|378773985|YP_005176228.1|Pasteurella_multocida_36950|-|54272..56323|topB1|Pmu_03290|DNA 
topoisomerase 
III
Length=683

 Score =  572 bits (2160),  Expect = 3e-164, Method: Compositional matrix adjust.
 Identities = 317/648 (49%), Positives = 471/648 (73%), Gaps = 5/648 (0%)

Query  1    MRLFLCEKPSQGRDIAKVLGATRRGDGCLIGTDST--VTWCIGHLLETAPPEAYGAQYKS  58
            M+LF+CEKPSQ+RD+A VLGAT +G+G L  +D +  VTW +GHL+E   PE Y+   K 
Sbjct  1    MKLFICEKPSQARDLAGVLGATSKGEGLLATADKSIIVTWGFGHLVEQYQPEDYDEAWKR  60

Query  59   WSLDHLPIIPAQWQVEVKSKTAAQFKIIKRLLSEASSVVIATDADREGEMIARELLELCR  118
            W+++ LPIIPAQW++  K  +  Q+ ++  L+  A+SVVIATDADREGEMIARELL+L  
Sbjct  61   WAFETLPIIPAQWKMTPKKESKKQYSVVIGLIKKATSVVIATDADREGEMIARELLDLAG  120

Query  119  YRGPVLRLWLSALNEASIRKALSSLKSGQVTFPLYHSALARSRADWLIGMNLSRLFTLLG  178
            YRG + R WLSAL++ASIRKAL +LKSG+ T +LY ++++RSR+DWLIGMN+SRLFTL++
Sbjct  121  YRGQIQRCWLSALDDASIRKALQTLKSGKETEALYYAGMGRSRSDWLIGMNFSRLFTLMA  180

Query  179  RRAGYDG-VLSVGRVQTPTLRLVVDRDRAIASFVPVPYWTVDVHLSSM-GQRFIASWLPP  236
            +  GY G  LSVGRVQ+PTL LVV+RDR IA+FVP +  ++ V+L++  G+ F+A+   P
Sbjct  181  QAKGYSGKPLSVGRVQSPTLTLVVNRDREIANFVPKSHYALAVQLTTTSGETFVAGLAVP  240

Query  237  RSGRDEAGRCLQQALAHHAVQTITGEKSATVLSLQTEQLREPPPLPFDLSTLQEVCSRKL  296
                DE+G CL+  + ++A   I     A V++++T + + +PPL + LS LQ  C+R +
Sbjct  241  EQYLDESGLCLDSRVIQQAEAQIKQTGLAKVVTVETKREKKSPPLLYALSDLQGECNRLF  300

Query  297  GLGVQETLNIAQALYETHKATTYPRSDCRYLPESMFNEAPAVLDALLKTDPALRPAFGSL  356
            G+G Q+ L+IAQ+LYE HK TTYPR+DC YLPES F++ P V+ +L+ +D++L+  +  L
Sbjct  301  GFGAQQVLDIAQSLYEEHKITTYPRTDCGYLPESQFSDVPNVIRSLVASDSGLQTLLPKL  360

Query  357  DRSLRARVWNNAKVTAHHGIIPTTEPANLVRMSEQERQVYELIRSHYLAQFLPHHEFDRT  416
            +   ++R W++ K+TAHHGIIPT   A+L ++SE+E +VY+LIR +YLAQFLPH E D+T
Sbjct  361  NLRQKSRAWDDKKITAHHGIIPTIKKADLSKLSEEEMKVYDLIRRRYLAQFLPHLEMDKT  420

Query  417  QVELECSKERLTAVGKQILIQGWKGLLTENTEDDEPSQKH-QVLPVLQQGTQCAVNDVEL  475
               L+ S + L A G+ I+ QGW+ L+  N +++  ++ + Q LPVL +  QC V + E+
Sbjct  421  VATLQSSGHTLVARGNVIVAQGWRILFGKNVDEETGNDDEKQGLPVLTKNQQCNVTHSEV  480

Query  476  KSMRTVAPKPLTEGDLIKAMKNVAKLVNDPRLKQKLRDTTGIGTEATRAGIIKGLVDRGY  535
            ++++T +P   TEG L+ AMKN A++V DPRLKQ+LR+T G+GTEATRAG+I+GL+D+G+
Sbjct  481  RTLQTKPPAHYTEGTLLDAMKNAARFVTDPRLKQRLRETEGLGTEATRAGLIQGLIDKGF  540

Query  536  LLKKKRALMASAAAHTLIEAAPTAVADPGMTAIWEQALDEIEAGRLTLDAFVAKQANWIA  595
            LLKKK++L+ASA A +LI++ P  + +PG+TA+WEQAL++I  G +TLDAF+ KQ   + 
Sbjct  541  LLKKKKSLVASAEAVALIDSLPDLLKNPGLTALWEQALNQIAEGSMTLDAFMQKQEAFVK  600

Query  596  QLVAHYRSHTLAIAVETSPSCPMCNASMLRRKGKSGPFWSCSCYPDCK  643
            QL++    + ++++      C+ C  +M + +   G FW+C+ YPDC+
Sbjct  601  QLIGSCMQQGMSLGNIEIRKCSECGKPMRKINHAKGTFWGCTGYPDCQ  648

> NC_016808_R1|63|G56|378773985|YP_005176228.1|Pasteurella_multocida_36950|-|54272..56323|topB1|Pmu_03290|DNA 
topoisomerase 
III
Length=683

 Score =  571 bits (2157),  Expect = 4e-164, Method: Compositional matrix adjust.
 Identities = 320/648 (50%), Positives = 475/648 (74%), Gaps = 4/648 (0%)

Query  1    MRLFLCEKPSQGRDIAKVLGASRRGDGCLI--GRETTVTWCIGHLLETAPPEAYGDQYKT  58
            M+LF+CEKPSQ+RD+A VLGA+ +G+G L   ++   VTW +GHL+E   PE Y++  K 
Sbjct  1    MKLFICEKPSQARDLAGVLGATSKGEGLLATADKSIIVTWGFGHLVEQYQPEDYDEAWKR  60

Query  59   WSLDHLPIIPAQWRVEVKPKTVAQFKIIKHLLSEATTVVIATDADREGEMIARELLELCN  118
            W+++ LPIIPAQW++  K  +  Q+ ++  L+  AT+VVIATDADREGEMIARELL+L  
Sbjct  61   WAFETLPIIPAQWKMTPKKESKKQYSVVIGLIKKATSVVIATDADREGEMIARELLDLAG  120

Query  119  YRGSVERLWLSALNEASIRKALSSLKSSQETFPLYHSALARSRADWLIGMNLSRLFTLLG  178
            YRG ++R WLSAL++ASIRKAL +LKS++ET +LY ++++RSR+DWLIGMN+SRLFTL++
Sbjct  121  YRGQIQRCWLSALDDASIRKALQTLKSGKETEALYYAGMGRSRSDWLIGMNFSRLFTLMA  180

Query  179  RRAGY-GAVLSVGRVQTPTLRLVVERDRAIASFVSVPYWVVNAHLSSMGQQPFIASWIPP  237
            +  GY G  LSVGRVQ+PTL LVV+RDR IA+FV+ +   +  +L++ + + F+A+   P
Sbjct  181  QAKGYSGKPLSVGRVQSPTLTLVVNRDREIANFVPKSHYALAVQLTTTSGETFVAGLAVP  240

Query  238  SSGRDEAGRClqqalasqalqaisssKTATVVSLRTEHLREAPPLPFDLSTLQEVCSRKL  297
                DE+G CL+  +  QA   I  +  A VV++ T + + +PPL + LS LQ  C+R +
Sbjct  241  EQYLDESGLCLDSRVIQQAEAQIKQTGLAKVVTVETKREKKSPPLLYALSDLQGECNRLF  300

Query  298  GLGAQETLNIAQALYETHKATSYPRSDCRYLPESMFNEVAAVFDALLRMDPALRPALGSI  357
            G+GAQ+ L+IAQ+LYE HK T+YPR+DC YLPES F++V+ V+ +L+  D++L+  L  +
Sbjct  301  GFGAQQVLDIAQSLYEEHKITTYPRTDCGYLPESQFSDVPNVIRSLVASDSGLQTLLPKL  360

Query  358  DQSLRSRAWNDAKVTAHHGIIPTTEPANLGRMSEQERQVYELIRSHYLAQFLPHHEFDRT  417
            +   +SRAW+D K+TAHHGIIPT   A+L+++SE+E +VY+LIR +YLAQFLPH E D+T
Sbjct  361  NLRQKSRAWDDKKITAHHGIIPTIKKADLSKLSEEEMKVYDLIRRRYLAQFLPHLEMDKT  420

Query  418  EVELECSAERLTAVGKQILVQGWKGLLSDNPDDDEPSQKS-QVLPALQQGRQCAVDDVEL  476
               L+ S++ L A G+ I+ QGW+ L++ N D++  ++   Q LP L + +QC V + E+
Sbjct  421  VATLQSSGHTLVARGNVIVAQGWRILFGKNVDEETGNDDEKQGLPVLTKNQQCNVTHSEV  480

Query  477  KSMRTAAPKSLTEGDLIKAMKNVAKLVNDPRLKQKLRDTTGIGTEATRAGIIKGLIDRGY  536
            ++++T +P   TEG L+ AMKN A++V DPRLKQ+LR+T G+GTEATRAG+I+GLID+G+
Sbjct  481  RTLQTKPPAHYTEGTLLDAMKNAARFVTDPRLKQRLRETEGLGTEATRAGLIQGLIDKGF  540

Query  537  LLKKKRALMASATAHTLIEAVPAAVADPGMTAIWEQALDEIEAGRLSLDAFVAKQAHWIT  596
            LLKKK++L+ASA A +LI+++P  + +PG+TA+WEQAL++I  G ++LDAF+ KQ   + 
Sbjct  541  LLKKKKSLVASAEAVALIDSLPDLLKNPGLTALWEQALNQIAEGSMTLDAFMQKQEAFVK  600

Query  597  QLIANCGALTLSVPVEAGPVCPICNASMLRRKGKSGPFWSCSHYPDCK  644
            QLI++C    +S+       C+ C  +M + +   G FW+C+ YPDC+
Sbjct  601  QLIGSCMQQGMSLGNIEIRKCSECGKPMRKINHAKGTFWGCTGYPDCQ  648

> NC_016808_R1|63|G56|378773985|YP_005176228.1|Pasteurella_multocida_36950|-|54272..56323|topB1|Pmu_03290|DNA 
topoisomerase 
III
Length=683

 Score =  571 bits (2156),  Expect = 6e-164, Method: Compositional matrix adjust.
 Identities = 321/652 (50%), Positives = 474/652 (73%), Gaps = 8/652 (1%)

Query  1    MRLFLCEKPSQGKDIGRILGATQRGEGCLNGS--GVTVTWCIGHLVEAATPEAYDEQLKR  58
            M+LF+CEKPSQ++D++ +LGAT +GEG L  +  ++ VTW +GHLVE   PE YDE  KR
Sbjct  1    MKLFICEKPSQARDLAGVLGATSKGEGLLATADKSIIVTWGFGHLVEQYQPEDYDEAWKR  60

Query  59   WSIEQLPIIPQHWRVEVKPKTATQFKVVKALLAKATQLVIATDADREGELIAREIIELCG  118
            W++E LPIIP +W++  K  +  Q+ VV +L+ KAT +VIATDADREGE+IARE+++L G
Sbjct  61   WAFETLPIIPAQWKMTPKKESKKQYSVVIGLIKKATSVVIATDADREGEMIARELLDLAG  120

Query  119  YRGPIERLWLSALNDASIRAALGKLRPSAETLPMYHSALARSRADWLVGMNLSRLFTVLG  178
            YRG I+R WLSAL+DASIR AL  L+++ ET ++Y ++++RSR+DWL+GMN+SRLFT+++
Sbjct  121  YRGQIQRCWLSALDDASIRKALQTLKSGKETEALYYAGMGRSRSDWLIGMNFSRLFTLMA  180

Query  179  RQAGYDG-VLSVGRVQTPTLKLVVDRDREIAAFVSVPYWAIVVSLSA-GVQAFTAHWVPP  236
            +  GY G  LSVGRVQ+PTL LVV+RDREIA FV+ +  A+ V L++ + ++F A    P
Sbjct  181  QAKGYSGKPLSVGRVQSPTLTLVVNRDREIANFVPKSHYALAVQLTTTSGETFVAGLAVP  240

Query  237  NACTDDAGRCLqqpvaqqamqqIRAAGSAHVVSVETERVREGPPLPFDLGTLQEVCSKQL  296
            +   D++G CL+  V QQA  QI+ +G A VV+VET R + +PPL + L+ LQ  C++ +
Sbjct  241  EQYLDESGLCLDSRVIQQAEAQIKQTGLAKVVTVETKREKKSPPLLYALSDLQGECNRLF  300

Query  297  GLDVQETLEIAQALYETHKATTYPRSDSGYLPESMFAEVTTVLDSLLKTDPSLRSIIGQL  356
            G++ Q+ L+IAQ+LYE HK TTYPR+D GYLPES F++V  V+ SL+ +D++L++++ +L
Sbjct  301  GFGAQQVLDIAQSLYEEHKITTYPRTDCGYLPESQFSDVPNVIRSLVASDSGLQTLLPKL  360

Query  357  DRLQRSRAWNDGKVTAHHGIIPTLEPANLSAMSEKELAVYRLIRAHYLAQFLPHHEFDHT  416
            +  Q+SRAW+D K+TAHHGIIPT+  A+LS +SE E+ VY LIR +YLAQFLPH E D T
Sbjct  361  NLRQKSRAWDDKKITAHHGIIPTIKKADLSKLSEEEMKVYDLIRRRYLAQFLPHLEMDKT  420

Query  417  VAKLSCGGQNLAATGKQVVTPGWRQVLAEPQSEdgdgdgdTAARAQVLPALHEGLACQVA  476
            VA L  +G+ L A G+ +V+ GWR +++    E    + +     Q LP L     C+V+
Sbjct  421  VATLQSSGHTLVARGNVIVAQGWRILFGKNVDE----ETGNDDEKQGLPVLTKNQQCNVT  476

Query  477  DIDLKALKTLPPKPYTQGELVKSMKGVAKLVSDPRLKQKLKDTVGIGTEATRANIIGGLI  536
            + ++++L+T PP  YT+G L+ +MK  A++V+DPRLKQ+L++T G+GTEATRA +I GLI
Sbjct  477  HSEVRTLQTKPPAHYTEGTLLDAMKNAARFVTDPRLKQRLRETEGLGTEATRAGLIQGLI  536

Query  537  ARGYLVKKGRAIRASDAAFTLIDAVPAAIADPGTTAVWEQALDMIEAGQLTLDVFIGKQA  596
             +G+L+KK +++ AS  A +LID++P  + +PG TA+WEQAL+ I  G +TLD F+ KQ 
Sbjct  537  DKGFLLKKKKSLVASAEAVALIDSLPDLLKNPGLTALWEQALNQIAEGSMTLDAFMQKQE  596

Query  597  AWISQLIAQYGNASLSIKAPQGPTCPQCGAPTRQRSSKSGPFWSCSRYPDCK  648
            A + QLI+   + ++S+   +   C++CG P R+ +   G FW+C+ YPDC+
Sbjct  597  AFVKQLIGSCMQQGMSLGNIEIRKCSECGKPMRKINHAKGTFWGCTGYPDCQ  648

> NC_016808_R1|63|G56|378773985|YP_005176228.1|Pasteurella_multocida_36950|-|54272..56323|topB1|Pmu_03290|DNA 
topoisomerase 
III
Length=683

 Score =  571 bits (2155),  Expect = 7e-164, Method: Compositional matrix adjust.
 Identities = 332/651 (51%), Positives = 481/651 (74%), Gaps = 8/651 (1%)

Query  1    MRLYLCEKPSQGKDIAAVLGAKTRGDG--CIKGNGVAVTWGIGHLLETAPPDAYGEHLKN  58
            M+L++CEKPSQ++D+A+VLGA ++G+G     ++++ VTWG+GHL+E   P+ Y+E  K 
Sbjct  1    MKLFICEKPSQARDLAGVLGATSKGEGLLATADKSIIVTWGFGHLVEQYQPEDYDEAWKR  60

Query  59   WSLDTLPILPAEWKVLVKPKTASQFKIVKQLLKQATELVIATDADREGEMIARELIEYCG  118
            W+++TLPI+PA+WK+  K  +  Q+ +V  L+K+AT +VIATDADREGEMIAREL++  G
Sbjct  61   WAFETLPIIPAQWKMTPKKESKKQYSVVIGLIKKATSVVIATDADREGEMIARELLDLAG  120

Query  119  YRGPIQRLWLSALNEASIRQALNTVKQGSETYPLYLSALARSRADWLIGMNFSRLFTLLG  178
            YRG IQR WLSAL++ASIR+AL+T+K G ET +LY ++++RSR+DWLIGMNFSRLFTL++
Sbjct  121  YRGQIQRCWLSALDDASIRKALQTLKSGKETEALYYAGMGRSRSDWLIGMNFSRLFTLMA  180

Query  179  RQAGYTG-VLSVGRVQTPTLRLVVDRDRDISNFIPKPFWSVEVQL-WTAGQSFLAKW-VA  235
            +  GY+G  LSVGRVQ+PTL LVV+RDR+I+NF+PK+  ++ VQL  T+G++F+A   V+
Sbjct  181  QAKGYSGKPLSVGRVQSPTLTLVVNRDREIANFVPKSHYALAVQLTTTSGETFVAGLAVP  240

Query  236  DEYLVDEEGRCLDqaaaaaalaalkssqaasTVSVDTKRGKDPAPLPFDLSTLQEVCSAK  295
            ++YL DE G CLD      A A +K +  A  V+V+TKR K ++PL + LS LQ  C+  
Sbjct  241  EQYL-DESGLCLDSRVIQQAEAQIKQTGLAKVVTVETKREKKSPPLLYALSDLQGECNRL  299

Query  296  FGMGVQETLDVAQSLYETHKATTYPRTDCGYLPESMFDEVPMVLDALNRTDPSIGKTLQL  355
            FG G Q+ LD+AQSLYE HK TTYPRTDCGYLPES F +VP V+ +L  +D+++   L  
Sbjct  300  FGFGAQQVLDIAQSLYEEHKITTYPRTDCGYLPESQFSDVPNVIRSLVASDSGLQTLLPK  359

Query  356  IDPEQRSRAWNDKKITGPHHGIIPTLEPANLSAMSEKERKVYELIRAHFLAQFLPTHEYD  415
            ++  Q+SRAW+DKKIT+ HHGIIPT+  A+LS +SE E KVY+LIR ++LAQFLP  E D
Sbjct  360  LNLRQKSRAWDDKKITA-HHGIIPTIKKADLSKLSEEEMKVYDLIRRRYLAQFLPHLEMD  418

Query  416  RTVATFECNAVLLQAVGKRIVIPGWKVLFSASSEEEANDSGGRSQILPVLQIGTRCDVQD  475
            +TVAT++ ++  L A G+ IV  GW++LF+ + +EE+ + + + Q LPVL    +C+V +
Sbjct  419  KTVATLQSSGHTLVARGNVIVAQGWRILFGKNVDEETGNDDEK-QGLPVLTKNQQCNVTH  477

Query  476  LHLKSLKTEPPKAYTEGTLIKAMKTIAKLVKDPRLAQKLKETTGIGTEATRAGTIQGLID  535
             ++++L+T PP  YTEGTL+ AMK  A++V DPRL Q+L+ET G+GTEATRAG IQGLID
Sbjct  478  SEVRTLQTKPPAHYTEGTLLDAMKNAARFVTDPRLKQRLRETEGLGTEATRAGLIQGLID  537

Query  536  RGSLIKKGSALRATEAAFSLIDAVPPAVADPGTTAIWEQALTMIEQGTLTLDDFIARQSS  595
            +G L+KK  +L A+  A +LID++P  + +PG TA+WEQAL  I +G++TLD F+ +Q +
Sbjct  538  KGFLLKKKKSLVASAEAVALIDSLPDLLKNPGLTALWEQALNQIAEGSMTLDAFMQKQEA  597

Query  596  WITRLVEQYKGTTLSIKVPEGPKCPLCSAKTSQRKGSSGVFWACSRYPECK  646
             + +L+       +S+   E  KC+ C+    + + + G FW+C+ YP+C+
Sbjct  598  FVKQLIGSCMQQGMSLGNIEIRKCSECGKPMRKINHAKGTFWGCTGYPDCQ  648

> NC_016808_R1|63|G56|378773985|YP_005176228.1|Pasteurella_multocida_36950|-|54272..56323|topB1|Pmu_03290|DNA 
topoisomerase 
III
Length=683

 Score =  569 bits (2149),  Expect = 2e-163, Method: Compositional matrix adjust.
 Identities = 320/649 (50%), Positives = 471/649 (73%), Gaps = 7/649 (1%)

Query  1    MRLFLCEKPSQGRDIATVLGATRRGDGCLIGTETT--VTWCIGHLLETAPPEAYGIQYKN  58
            M+LF+CEKPSQ+RD+A VLGAT +G+G L  ++ +  VTW +GHL+E   PE Y+   K 
Sbjct  1    MKLFICEKPSQARDLAGVLGATSKGEGLLATADKSIIVTWGFGHLVEQYQPEDYDEAWKR  60

Query  59   WSLDHLPIIPAQWKVEVKHKTAAQFKVIKRLLSEASAVVIATDADREGEMIARELLELCN  118
            W+++ LPIIPAQWK+  K  +  Q+ V+  L+  A++VVIATDADREGEMIARELL+L  
Sbjct  61   WAFETLPIIPAQWKMTPKKESKKQYSVVIGLIKKATSVVIATDADREGEMIARELLDLAG  120

Query  119  YRGPVERLWLSALNEVSILKALSSLKSGQETFPLYHSALARSRADWLIGMNLSRLFTLLG  178
            YRG ++R WLSAL++ SI KAL +LKSG+ET +LY ++++RSR+DWLIGMN+SRLFTL++
Sbjct  121  YRGQIQRCWLSALDDASIRKALQTLKSGKETEALYYAGMGRSRSDWLIGMNFSRLFTLMA  180

Query  179  RRAGYDG-VLSVGRVQTPTLRLVVDRDRAIASFVSVPYWDVEVHLSFM-GQSFIASWLPP  236
            +  GY G  LSVGRVQ+PTL LVV+RDR IA+FV+ +   + V+L+   G++F+A+   P
Sbjct  181  QAKGYSGKPLSVGRVQSPTLTLVVNRDREIANFVPKSHYALAVQLTTTSGETFVAGLAVP  240

Query  237  SSGRDEACRCLQQALARHAGQTITDGKTATVLSLQTEHFREPPPLPFDLSTLQEVCSRKL  296
                DE+  CL+  + ++A   I +   A V++++T + + +PPL + LS LQ  C+R +
Sbjct  241  EQYLDESGLCLDSRVIQQAEAQIKQTGLAKVVTVETKREKKSPPLLYALSDLQGECNRLF  300

Query  297  GLGVQETLNIAQALYETHKATTYPRSDCRYLPASMFDEVPTVFDALLKTDSALQPAFEKL  356
            G+G Q+ L+IAQ+LYE HK TTYPR+DC YLP S F +VP V+ +L+ +DS+LQ  + KL
Sbjct  301  GFGAQQVLDIAQSLYEEHKITTYPRTDCGYLPESQFSDVPNVIRSLVASDSGLQTLLPKL  360

Query  357  DRSLRSRAWNDAKATAHHGIIPTTEPANLARMSEQERQVYEQIRNHYLAQFLPHHEFDRT  416
            +   +SRAW+D K TAHHGIIPT   A+L+++SE+E +VY+ IR +YLAQFLPH E D+T
Sbjct  361  NLRQKSRAWDDKKITAHHGIIPTIKKADLSKLSEEEMKVYDLIRRRYLAQFLPHLEMDKT  420

Query  417  QVELECGKERLTAVGKQILVQSWKGLLYDNTEDDEPS--QKFQVLPVLQQGTQCAVNDVE  474
               L+ + + L A G+ I+ Q+W+ +L+++  D+E +  +  Q LPVL +  QC V + E
Sbjct  421  VATLQSSGHTLVARGNVIVAQGWR-ILFGKNVDEETGNDDEKQGLPVLTKNQQCNVTHSE  479

Query  475  LKSMRTTAPKPLTEGDLIKAMKNVAKLVNDPRLKQKLRDTTGIGTEATRAGIIKGLIDRG  534
            +++++T +P   TEG L+ AMKN A++V DPRLKQ+LR+T G+GTEATRAG+I+GLID+G
Sbjct  480  VRTLQTKPPAHYTEGTLLDAMKNAARFVTDPRLKQRLRETEGLGTEATRAGLIQGLIDKG  539

Query  535  YLLKKKRALMASAAAHTLIEAVPAAIADPGMTAIWEQALDEIEAGRLSLDAFVAKQASWI  594
            +LLKKK++L+ASA A +LI+++P  + +PG+TA+WEQAL++I  G ++LDAF+ KQ + +
Sbjct  540  FLLKKKKSLVASAEAVALIDSLPDLLKNPGLTALWEQALNQIAEGSMTLDAFMQKQEAFV  599

Query  595  AQLVEHCRALTLALPVETGPACPICNASMLRRTGKSGAFWSCSHYPDCK  643
             QL+  C    ++L       C+ C  +M +     G+FW+C+ YPDC+
Sbjct  600  KQLIGSCMQQGMSLGNIEIRKCSECGKPMRKINHAKGTFWGCTGYPDCQ  648

> NC_016808_R1|63|G56|378773985|YP_005176228.1|Pasteurella_multocida_36950|-|54272..56323|topB1|Pmu_03290|DNA 
topoisomerase 
III
Length=683

 Score =  568 bits (2143),  Expect = 5e-163, Method: Compositional matrix adjust.
 Identities = 328/650 (51%), Positives = 481/650 (74%), Gaps = 6/650 (0%)

Query  1    MRVFLCEKPSQGKDIARVLGAGQRGNG--CYSGAGVVVTWCIGHLVEAVPPEGYGEQYKR  58
            M++F+CEKPSQ++D+A VLGA  +G+G    ++ +++VTW +GHLVE   PE+Y+E  KR
Sbjct  1    MKLFICEKPSQARDLAGVLGATSKGEGLLATADKSIIVTWGFGHLVEQYQPEDYDEAWKR  60

Query  59   WAIEQLPILPERWRVEPKSATAAQFKVVQQLVAKAGELVIATDADREGEMIAREIIDLCS  118
            WA+E LPI+P +W++ PK  +  Q+ VV  L+ KA  +VIATDADREGEMIARE++DL +
Sbjct  61   WAFETLPIIPAQWKMTPKKESKKQYSVVIGLIKKATSVVIATDADREGEMIARELLDLAG  120

Query  119  YRGPIQRLWLSALNDVSIRKALGALKPSAETLPLYFSALARSRADWLIGMNLSRLFTLLG  178
            YRG IQR WLSAL+D SIRKAL +LK++ ET +LY+++++RSR+DWLIGMN+SRLFTL++
Sbjct  121  YRGQIQRCWLSALDDASIRKALQTLKSGKETEALYYAGMGRSRSDWLIGMNFSRLFTLMA  180

Query  179  RQAGYTG-VLSVGRVQTPTLKLVVDRDREIARFVCVPFWAIEVALSHA-GQSFVASWTPP  236
            +  GY+G  LSVGRVQ+PTL LVV+RDREIA FV  +  A+ V L+ + G++FVA+ + P
Sbjct  181  QAKGYSGKPLSVGRVQSPTLTLVVNRDREIANFVPKSHYALAVQLTTTSGETFVAGLAVP  240

Query  237  QGSTDDAGRCLQQPVAQQAVERLRTAGAAQVRSVETERVREGPPLPFDLGTLQEVCSKQL  296
            +   D++G CL+  V QQA  +++ +G A+V +VET R + +PPL + L+ LQ  C++ +
Sbjct  241  EQYLDESGLCLDSRVIQQAEAQIKQTGLAKVVTVETKREKKSPPLLYALSDLQGECNRLF  300

Query  297  GLDVQETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPTVLDSMVKTDPSLRPLIERL  356
            G++ Q+ LDIAQ+LYE HK TTYPR+D GYLPES +++VP V+ S+V +D++L+ L+ +L
Sbjct  301  GFGAQQVLDIAQSLYEEHKITTYPRTDCGYLPESQFSDVPNVIRSLVASDSGLQTLLPKL  360

Query  357  DRQQRSRAWNDGKVSAHHGIIPTLEPANLSAMNEKELAVYRLIRAHYLAQFLPHHEFDRT  416
            + +Q+SRAW+D K++AHHGIIPT+  A+LS ++E E+ VY LIR +YLAQFLPH E D+T
Sbjct  361  NLRQKSRAWDDKKITAHHGIIPTIKKADLSKLSEEEMKVYDLIRRRYLAQFLPHLEMDKT  420

Query  417  VAQFSCGSQSLAAVGKQIAVIGWREVLATPGPDDADGEDAQRSQVLPALHAGLSCPVGKV  476
            VA +  ++++L A G+ I   GWR +L     D+  G+D ++ Q LP L     C V   
Sbjct  421  VATLQSSGHTLVARGNVIVAQGWR-ILFGKNVDEETGNDDEK-QGLPVLTKNQQCNVTHS  478

Query  477  DLKALKTLPPKPYTQGELIKAMKTVAKFVTDPRLKQKLRDTTGIGTEATRANIINGLIGR  536
            ++++L+T PP  YT+G L+ AMK  A+FVTDPRLKQ+LR+T G+GTEATRA +I+GLI++
Sbjct  479  EVRTLQTKPPAHYTEGTLLDAMKNAARFVTDPRLKQRLRETEGLGTEATRAGLIQGLIDK  538

Query  537  GYLVKKGRAVRASDAAFTLIDAVPSAIADPGTTAVWEHALDMIEAGQMALDTFIEKQAAW  596
            G+L+KK +++ AS  A +LID++P  + +PG TA+WE+AL+ I  G M+LD+F++KQ A 
Sbjct  539  GFLLKKKKSLVASAEAVALIDSLPDLLKNPGLTALWEQALNQIAEGSMTLDAFMQKQEAF  598

Query  597  VGQLVQQYRGATLSLKLppapacpqcgapmqqRTGKSGAFWSCSRYPDCK  646
            V QL+       +SL       C++CG PM++     G+FW+C+ YPDC+
Sbjct  599  VKQLIGSCMQQGMSLGNIEIRKCSECGKPMRKINHAKGTFWGCTGYPDCQ  648

> NC_016808_R1|63|G56|378773985|YP_005176228.1|Pasteurella_multocida_36950|-|54272..56323|topB1|Pmu_03290|DNA 
topoisomerase 
III
Length=683

 Score =  567 bits (2140),  Expect = 1e-162, Method: Compositional matrix adjust.
 Identities = 329/650 (51%), Positives = 481/650 (74%), Gaps = 6/650 (0%)

Query  1    MRVFLCEKPSQGKDIARVLGAGQRGNG--CYSGAGVVVTWCIGHLVEAVPPEGYGEQYKR  58
            M++F+CEKPSQ++D+A VLGA  +G+G    ++ +++VTW +GHLVE   PE+Y+E  KR
Sbjct  1    MKLFICEKPSQARDLAGVLGATSKGEGLLATADKSIIVTWGFGHLVEQYQPEDYDEAWKR  60

Query  59   WAIEQLPILPERWRVEPKAATAAQFKVVQQLVAKAGELVIATDADREGEMIAREIIDLCG  118
            WA+E LPI+P +W++ PK  +  Q+ VV  L+ KA  +VIATDADREGEMIARE++DL G
Sbjct  61   WAFETLPIIPAQWKMTPKKESKKQYSVVIGLIKKATSVVIATDADREGEMIARELLDLAG  120

Query  119  YRGPIQRLWLSALNDASIRKALGALKPSDETLPLYFSALARSRADWLIGMNLSRLFTLLG  178
            YRG IQR WLSAL+DASIRKAL +LK++ ET +LY+++++RSR+DWLIGMN+SRLFTL++
Sbjct  121  YRGQIQRCWLSALDDASIRKALQTLKSGKETEALYYAGMGRSRSDWLIGMNFSRLFTLMA  180

Query  179  RQAGYTG-VLSVGRVQTPTLKLVVDRDREIARFVCVPFWAIEVALSHA-GQSFVASWTPP  236
            +  GY+G  LSVGRVQ+PTL LVV+RDREIA FV  +  A+ V L+ + G++FVA+ + P
Sbjct  181  QAKGYSGKPLSVGRVQSPTLTLVVNRDREIANFVPKSHYALAVQLTTTSGETFVAGLAVP  240

Query  237  QGSADDADRCLQQPVAQQAAEFLRAAGTAQVLSVETERVREGPPLPFDLGTLQEVCSKQL  296
            +   D+++ CL+  V QQA   ++ +G A+V++VET R + +PPL + L+ LQ  C++ +
Sbjct  241  EQYLDESGLCLDSRVIQQAEAQIKQTGLAKVVTVETKREKKSPPLLYALSDLQGECNRLF  300

Query  297  GLDVQETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPTVLNSLVKTDPSLRPLIERL  356
            G++ Q+ LDIAQ+LYE HK TTYPR+D GYLPES +++VP V+ SLV +D++L+ L+ +L
Sbjct  301  GFGAQQVLDIAQSLYEEHKITTYPRTDCGYLPESQFSDVPNVIRSLVASDSGLQTLLPKL  360

Query  357  DRQQRSRAWNDGKVSAHHGIIPTLEPANLSAMNEKELAVYRLIRAHYLAQFLPHHEFDRT  416
            + +Q+SRAW+D K++AHHGIIPT+  A+LS ++E E+ VY LIR +YLAQFLPH E D+T
Sbjct  361  NLRQKSRAWDDKKITAHHGIIPTIKKADLSKLSEEEMKVYDLIRRRYLAQFLPHLEMDKT  420

Query  417  VAQFSCGSQSLAAVGKQIAVIGWREVLATPGPDDADGEDAQRSQVLPALHAGLSCPVGKV  476
            VA +  ++++L A G+ I   GWR +L     D+  G+D ++ Q LP L     C V   
Sbjct  421  VATLQSSGHTLVARGNVIVAQGWR-ILFGKNVDEETGNDDEK-QGLPVLTKNQQCNVTHS  478

Query  477  DLKALKTLPPKPYTQGELIKAMKTVAKLVTDPRLKQKLRDTTGIGTEATRANIINGLIGR  536
            ++++L+T PP  YT+G L+ AMK  A++VTDPRLKQ+LR+T G+GTEATRA +I+GLI++
Sbjct  479  EVRTLQTKPPAHYTEGTLLDAMKNAARFVTDPRLKQRLRETEGLGTEATRAGLIQGLIDK  538

Query  537  GYLVKKGRAVRASDAAFTLIDAVPSAIADPGTTAVWEQALDMIEAGQMTLDTFIEKQSVW  596
            G+L+KK +++ AS  A +LID++P  + +PG TA+WEQAL+ I  G MTLD+F++KQ   
Sbjct  539  GFLLKKKKSLVASAEAVALIDSLPDLLKNPGLTALWEQALNQIAEGSMTLDAFMQKQEAF  598

Query  597  VGQLVQQYRGATLSLKLppapacpqcaapmqqRTGKSGAFWSCSRYPDCK  646
            V QL+       +SL       C++C+ PM++     G+FW+C+ YPDC+
Sbjct  599  VKQLIGSCMQQGMSLGNIEIRKCSECGKPMRKINHAKGTFWGCTGYPDCQ  648

> NC_016808_R1|63|G56|378773985|YP_005176228.1|Pasteurella_multocida_36950|-|54272..56323|topB1|Pmu_03290|DNA 
topoisomerase 
III
Length=683

 Score =  562 bits (2123),  Expect = 2e-161, Method: Compositional matrix adjust.
 Identities = 335/667 (51%), Positives = 484/667 (73%), Gaps = 5/667 (0%)

Query  1    MRVVLCEKPSQGKDIARVLGATQRGNG--CYTGSGLGVTWGIGHLIETAPPEAYGEQYKR  58
            M++ +CEKPSQ++D+A VLGAT +G+G    ++ ++ VTWG+GHL+E   PE Y+E  KR
Sbjct  1    MKLFICEKPSQARDLAGVLGATSKGEGLLATADKSIIVTWGFGHLVEQYQPEDYDEAWKR  60

Query  59   WALEPLPIIPQHWQVVVKAKTATQFKVVKQLLAQATDLVIATDADREGEMIARELIDYCG  118
            WA+E LPIIP +W++  K  +  Q+ VV  L+ +AT +VIATDADREGEMIAREL+D  G
Sbjct  61   WAFETLPIIPAQWKMTPKKESKKQYSVVIGLIKKATSVVIATDADREGEMIARELLDLAG  120

Query  119  YRGPIQRLWLSALNDASIRKALGALKPSGETLPLYYSALARSRADWLIGMNLSRLFTVLG  178
            YRG IQR WLSAL+DASIRKAL +LK++ ET +LYY++++RSR+DWLIGMN+SRLFT+++
Sbjct  121  YRGQIQRCWLSALDDASIRKALQTLKSGKETEALYYAGMGRSRSDWLIGMNFSRLFTLMA  180

Query  179  RQAGYSG-VLSVGRVQTPTLKLVVDRDREIARFVSVPFWTIEV-LLAHAGQSFVANWTPP  236
            +  GYSG  LSVGRVQ+PTL LVV+RDREIA FV+ +  ++ V L + +G++FVA  + P
Sbjct  181  QAKGYSGKPLSVGRVQSPTLTLVVNRDREIANFVPKSHYALAVQLTTTSGETFVAGLAVP  240

Query  237  AGCTDDAGRCLQQPVAQQADERMRAAVSAQVVSVETERMREGPPLPFDLGTLQEVCSKQL  296
                D++G CL+  V QQA+ +++ +  A+VV+VET R + +PPL + L+ LQ  C++ +
Sbjct  241  EQYLDESGLCLDSRVIQQAEAQIKQTGLAKVVTVETKREKKSPPLLYALSDLQGECNRLF  300

Query  297  GLDVQETLDIAQSLYETHKATTYPRSDSGYLPENMLAEVPTVLDSLVKTDPSLRPLVAKL  356
            G++ Q+ LDIAQSLYE HK TTYPR+D GYLPE+ +++VP V+ SLV +D++L+ L++KL
Sbjct  301  GFGAQQVLDIAQSLYEEHKITTYPRTDCGYLPESQFSDVPNVIRSLVASDSGLQTLLPKL  360

Query  357  DPHQRSRAWNDAKVTAHHGIIPTLEPANLSALNDKELAVYRLIRAHYLAQFLPHHEFDRT  416
            + +Q+SRAW+D K+TAHHGIIPT+  A+LS L++ E+ VY LIR +YLAQFLPH E D+T
Sbjct  361  NLRQKSRAWDDKKITAHHGIIPTIKKADLSKLSEEEMKVYDLIRRRYLAQFLPHLEMDKT  420

Query  417  VAQFACAGQSLTVVGKQIVVTGWRQVLaapapdepdedaQRSQVLPALHAGLSCPIGAVD  476
            VA +  +G++L   G+ IV  GWR +L +   DE   + +  Q LP L     C +   +
Sbjct  421  VATLQSSGHTLVARGNVIVAQGWR-ILFGKNVDEETGNDDEKQGLPVLTKNQQCNVTHSE  479

Query  477  LKALKTLPPKPYTQGELVKAMKGVARLVTDPRLKQKLKDTTGIGTEATRANIINgllgrg  536
            +++L+T PP  YT+G L+ AMK  AR+VTDPRLKQ+L++T G+GTEATRA +I+GL+++G
Sbjct  480  VRTLQTKPPAHYTEGTLLDAMKNAARFVTDPRLKQRLRETEGLGTEATRAGLIQGLIDKG  539

Query  537  yllkkgrAIRASDAAFTLIDAVPPAIADPGTTAVWEQALDMIEARQMTLDAFIAKQSAWV  596
            +LLKK +++ AS  A +LID++P  + +PG TA+WEQAL+ I    MTLDAF+ KQ A V
Sbjct  540  FLLKKKKSLVASAEAVALIDSLPDLLKNPGLTALWEQALNQIAEGSMTLDAFMQKQEAFV  599

Query  597  AQLVQQYRTATLSIQLPPAPACPQCGSPMRQRTGKSGAFWSCSRYPDCKGTMAIESATGG  656
             QL+       +S+       C++CG PMR+     G+FW+C+ YPDC+   A     ++
Sbjct  600  KQLIGSCMQQGMSLGNIEIRKCSECGKPMRKINHAKGTFWGCTGYPDCQHKEADKKVKSA  659

Query  657  KRSAPRK  663
               +++K
Sbjct  660  SNKSAKK  666

> NC_016808_R1|63|G56|378773985|YP_005176228.1|Pasteurella_multocida_36950|-|54272..56323|topB1|Pmu_03290|DNA 
topoisomerase 
III
Length=683

 Score =  562 bits (2121),  Expect = 3e-161, Method: Compositional matrix adjust.
 Identities = 330/657 (51%), Positives = 473/657 (72%), Gaps = 17/657 (2%)

Query  3    RLFLCEKPTQARDIAKVLGASEKGNGCLK--GRGITVTWGFGHLLEQANPEAYDPALKRW  60
            +LF+CEKP+QARD+A VLGA+ KG+G L   +++I VTWGFGHL+EQ +PE YD A KRW
Sbjct  2    KLFICEKPSQARDLAGVLGATSKGEGLLATADKSIIVTWGFGHLVEQYQPEDYDEAWKRW  61

Query  61   SMESLPILPTQWKLEVKPSAKKQFTVVKKLLSSASEVVIATDADREGEMIAREILEACQF  120
            + E+LPI+P+QWK+  K  +KKQ++VV  L+  A+ VVIATDADREGEMIARE+L+   +
Sbjct  62   AFETLPIIPAQWKMTPKKESKKQYSVVIGLIKKATSVVIATDADREGEMIARELLDLAGY  121

Query  121  SGGVSRLWLPALDEASIRKALGDIRPGESTRLLYHAALGRSRADWLVGMNLTRAFTMRAK  180
             G + R WL+ALD+ASIRKAL  +++G  T  LY A++GRSR+DWL+GMN++R FT+ A+
Sbjct  122  RGQIQRCWLSALDDASIRKALQTLKSGKETEALYYAGMGRSRSDWLIGMNFSRLFTLMAQ  181

Query  181  QLGY-DLLLSVGRVQTPVLKLVVDRDREIANFVPKPFWEV-VAVFQAEGGTFQAKWQPAD  238
              GY +  LSVGRVQ+P L LVV+RDREIANFVPK+   + V +  + G TF A   +  
Sbjct  182  AKGYSGKPLSVGRVQSPTLTLVVNRDREIANFVPKSHYALAVQLTTTSGETFVAG-LAVP  240

Query  239  DDVLDESGRCINQSAAQAVVARCQ--GLPGQVTTLETTRKREAPPLAMDLGTLQQTCSKR  296
            ++ LDESG C++    Q   A+ +  GL ++V T+ET R + +PPL   L+ LQ  C++ 
Sbjct  241  EQYLDESGLCLDSRVIQQAEAQIKQTGL-AKVVTVETKREKKSPPLLYALSDLQGECNRL  299

Query  297  WGYGAQQVLDIAQALYETHKATTYPRTDCRYLPLSQLDDAQQVVTALLTSDGELAPVVQS  356
             G+GAQQVLDIAQ+LYE HK TTYPRTDC YLP SQ+ D  +V+ +L++SD+ L  ++  
Sbjct  300  FGFGAQQVLDIAQSLYEEHKITTYPRTDCGYLPESQFSDVPNVIRSLVASDSGLQTLLPK  359

Query  357  LDLTRKSRVWNDSKITAHHGIIPTTSPCDTSKMSEAEWNVYDLVRRHYLAQFLPPHEYDH  416
            L+L +KSR W+D KITAHHGIIPT    D SK+SE E +VYDL+RR+YLAQFLP  E D 
Sbjct  360  LNLRQKSRAWDDKKITAHHGIIPTIKKADLSKLSEEEMKVYDLIRRRYLAQFLPHLEMDK  419

Query  417  TDVALEVAGERFATTGRQVQVEGWKVLF-RNVQQDDAAGDEATAKTSSQALPPLQAHANV  475
            T  +L+ +G+ + + G  +  +GW++LF +NV+++ + +DE       Q+LP L  + + 
Sbjct  420  TVATLQSSGHTLVARGNVIVAQGWRILFGKNVDEETGNDDE------KQGLPVLTKNQQC  473

Query  476  PQSSLDLVSKTTTPPKPFAEGTLIGAMKNAARFEPNPKLKARLKESAGIGTEATRAGIIE  535
              +  ++ +  T PP  ++EGTL++AMKNAARF  +P+LK RL+E+ G+GTEATRAG+I+
Sbjct  474  NVTHSEVRTLQTKPPAHYTEGTLLDAMKNAARFVTDPRLKQRLRETEGLGTEATRAGLIQ  533

Query  536  TLLKRKFLTKKGRAIVATATGRQLIDALPEVVTNPGMTALWEQALDSVAAGELSLEDFMA  595
             L+ + FL KK +++VA+A +  LID+LP+++ NPG+TALWEQAL+ +A G ++L+ FM 
Sbjct  534  GLIDKGFLLKKKKSLVASAEAVALIDSLPDLLKNPGLTALWEQALNQIAEGSMTLDAFMQ  593

Query  596  KQQTLVERLIEQAKSATINLPQEPAKSKACPECGAPMKKRKNDYGSFWGCTKYPDCK  652
            KQ+++V +LI       ++L +     + C+ECG PM+K ++  G+FWGCT YPDC+
Sbjct  594  KQEAFVKQLIGSCMQQGMSLGN--IEIRKCSECGKPMRKINHAKGTFWGCTGYPDCQ  648

> NC_016808_R1|63|G56|378773985|YP_005176228.1|Pasteurella_multocida_36950|-|54272..56323|topB1|Pmu_03290|DNA 
topoisomerase 
III
Length=683

 Score =  561 bits (2118),  Expect = 5e-161, Method: Compositional matrix adjust.
 Identities = 331/674 (50%), Positives = 483/674 (72%), Gaps = 9/674 (1%)

Query  1    MRLFICEKPSQARDIAAVIGATKRGQGFLSAP--GITITWARGHLLETASPEVYGTQFEK  58
            M+LFICEKPSQARD+A+V+GAT +G+G+L+++  +I +TW+ GHL+E   PE Y+    K
Sbjct  1    MKLFICEKPSQARDLAGVLGATSKGEGLLATADKSIIVTWGFGHLVEQYQPEDYDEAW-K  59

Query  59   PWRIDVLPVLPPVWQMVVKPESLDQFTVISRLLKQVDEVVISTDADREGEVIGWSLLEYC  118
             W ++ LP++P+ W+M  K ES  Q++V+  L+K+   VVI+TDADREGE+I++ LL+  
Sbjct  60   RWAFETLPIIPAQWKMTPKKESKKQYSVVIGLIKKATSVVIATDADREGEMIARELLDLA  119

Query  119  GWRGPVFRLWLSALDESSIRTALAAIKPGAETKPLYYAGLGRSRADWLIGMNLTRLYTVK  178
            G RG + R WLSALD++SIR AL ++K+G ET +LYYAG+GRSR+DWLIGMN++RL+T+ 
Sbjct  120  GYRGQIQRCWLSALDDASIRKALQTLKSGKETEALYYAGMGRSRSDWLIGMNFSRLFTLM  179

Query  179  ARDKGYDG-LLSVGRVQTPVLAMVVNREREIAAFVPKPYWQVWVALQS-NGVRFSAQWVP  236
            A+ KGY G  LSVGRVQ+P L++VVNR+REIA FVPK+   + V L + +G  F A    
Sbjct  180  AQAKGYSGKPLSVGRVQSPTLTLVVNRDREIANFVPKSHYALAVQLTTTSGETFVAGLAV  239

Query  237  AKMYVDEEKRCIHQGIAQQVAQLCKQTGKATVIEQETKREKEAAPLAFTMGTLQQACGRL  296
            +  Y+DE   C++  + QQ     KQTG A V+  ETKREK ++PL ++++ LQ  C RL
Sbjct  240  PEQYLDESGLCLDSRVIQQAEAQIKQTGLAKVVTVETKREKKSPPLLYALSDLQGECNRL  299

Query  297  WDMSPQKVLDIAQSLYETHKATSYPRTDCGFLPESMREEIPDVLSALVKIDPSLQELIPQ  356
             + ++Q+VLDIAQSLYE HK T+YPRTDCG+LPES   ++P+V+ +LV  D++LQ L+P+
Sbjct  300  FGFGAQQVLDIAQSLYEEHKITTYPRTDCGYLPESQFSDVPNVIRSLVASDSGLQTLLPK  359

Query  357  LDTRFVSRIWDDKNITAHHGIIPTRHVSDMSKMSEQEKQVYLLIRRHYLAQFLPLHEVDA  416
            L+ R  SR WDDK+ITAHHGIIPT   +D+SK+SE+E +VY LIRR+YLAQFLP  E+D 
Sbjct  360  LNLRQKSRAWDDKKITAHHGIIPTIKKADLSKLSEEEMKVYDLIRRRYLAQFLPHLEMDK  419

Query  417  TRLSLNIGGQLFQTTGRVVVVPGWKRLFSQQDDGEHKESAADEKDQSLPMLVKGDNCAVT  476
            T  +L+ +G+ + + G V+V  GW+ LF+++ D    E++ D+  Q+LP+L K ++C VT
Sbjct  420  TVATLQSSGHTLVARGNVIVAQGWRILFGKNVDE---ETGNDDEKQGLPVLTKNQQCNVT  476

Query  477  GAEVKALKTKPPQYFTFQSLIAAMMNAAAYVTDLTLKKVLKENAGLGTEATRGGIVETLL  536
             +EV++L+TKPP  +T  +L+ AM NAA +VTD  LK+ L+E  GLGTEATR+G+++ L+
Sbjct  477  HSEVRTLQTKPPAHYTEGTLLDAMKNAARFVTDPRLKQRLRETEGLGTEATRAGLIQGLI  536

Query  537  ARNFIIIKGRYLRATDIAMDLIDALPHALKEPGMTALWEQALDEVAKGKMTLDNFMSRQT  596
             + F++ K + L A+  A+ LID+LP+ LK+PG+TALWEQAL+++A G MTLD FM +Q 
Sbjct  537  DKGFLLKKKKSLVASAEAVALIDSLPDLLKNPGLTALWEQALNQIAEGSMTLDAFMQKQE  596

Query  597  QWICQLVSLGAQQDVVVRVPPTPACPLCGSKTRLRKGVKGSFYGCEKYPDCKGMINIPGQ  656
              + QL++   QQ++ +       C+ CG   R  +  KG+F GC  YPDC+   +   +
Sbjct  597  AFVKQLIGSCMQQGMSLGNIEIRKCSECGKPMRKINHAKGTFWGCTGYPDCQHK-EADKK  655

Query  657  GKNTAPKTRKKKQN  670
             K+++ K+ KK  N
Sbjct  656  VKSASNKSAKKSSN  669

> NC_016808_R1|63|G56|378773985|YP_005176228.1|Pasteurella_multocida_36950|-|54272..56323|topB1|Pmu_03290|DNA 
topoisomerase 
III
Length=683

 Score =  561 bits (2118),  Expect = 5e-161, Method: Compositional matrix adjust.
 Identities = 331/673 (50%), Positives = 486/673 (73%), Gaps = 8/673 (1%)

Query  1    MRLFICEKPSQARDIAAVLGATKRGQGFLSAP--GITITWARGHLLETASPEVYGTQFEK  58
            M+LFICEKPSQARD+A+VLGAT +G+G+L+++  +I +TW+ GHL+E   PE Y+    K
Sbjct  1    MKLFICEKPSQARDLAGVLGATSKGEGLLATADKSIIVTWGFGHLVEQYQPEDYDEAW-K  59

Query  59   PWRIDVLPVLPPVWQMVVKSESSDQFTVISRLLKQVDEVVISTDADREGEVIGWSLLEYC  118
             W ++ LP++P+ W+M  K ES  Q++V+  L+K+   VVI+TDADREGE+I++ LL+  
Sbjct  60   RWAFETLPIIPAQWKMTPKKESKKQYSVVIGLIKKATSVVIATDADREGEMIARELLDLA  119

Query  119  GWRGPVFRLWLSALDESSIRAALAAIKPGSETKPLYYAGLGRSRADWLIGMNLTRLYTVK  178
            G RG + R WLSALD++SIR AL ++K+G ET +LYYAG+GRSR+DWLIGMN++RL+T+ 
Sbjct  120  GYRGQIQRCWLSALDDASIRKALQTLKSGKETEALYYAGMGRSRSDWLIGMNFSRLFTLM  179

Query  179  ARDKGYDG-LLSVGRVQTPVLAMVVNREREIATFVPKPYWQVWVALQS-NGVRFSAQWVP  236
            A+ KGY G  LSVGRVQ+P L++VVNR+REIA FVPK+   + V L + +G  F A    
Sbjct  180  AQAKGYSGKPLSVGRVQSPTLTLVVNRDREIANFVPKSHYALAVQLTTTSGETFVAGLAV  239

Query  237  AKMYVDEEKRCIHQDIAQQVAQLCKQTGKATVIEQETKREKEAAPLAFTMGTLQQACGRL  296
            +  Y+DE   C++  + QQ     KQTG A V+  ETKREK ++PL ++++ LQ  C RL
Sbjct  240  PEQYLDESGLCLDSRVIQQAEAQIKQTGLAKVVTVETKREKKSPPLLYALSDLQGECNRL  299

Query  297  WDMSPQKVLDIAQSLYETHKATSYPRTDCGFLPESMREEIPDVLSALVKIDPSLQALISQ  356
             + ++Q+VLDIAQSLYE HK T+YPRTDCG+LPES   ++P+V+ +LV  D++LQ+L+++
Sbjct  300  FGFGAQQVLDIAQSLYEEHKITTYPRTDCGYLPESQFSDVPNVIRSLVASDSGLQTLLPK  359

Query  357  LDTRFVSRIWDDKKMTAHHGIIPTRHVCDMSKMSDQEKQVYVLIRRHYLAQFFPLHEVDF  416
            L+ R  SR WDDKK+TAHHGIIPT    D+SK+S++E +VY LIRR+YLAQF+P  E+D 
Sbjct  360  LNLRQKSRAWDDKKITAHHGIIPTIKKADLSKLSEEEMKVYDLIRRRYLAQFLPHLEMDK  419

Query  417  TRLSLNIGGQLFQTTGRVVVVPGWKRLFSQDDGEHKEAAADEKDQSLPMLVKGDNCGVAG  476
            T  +L+ +G+ + + G V+V  GW+ LF+++ +E  E++ D+  Q+LP+L K ++C V+ 
Sbjct  420  TVATLQSSGHTLVARGNVIVAQGWRILFGKNVDE--ETGNDDEKQGLPVLTKNQQCNVTH  477

Query  477  SEVKALKTKPPQYFTFQSLIAAMMNAAAYVTDLTLKKVLKENAGLGTEATRGGIVETLLA  536
            SEV++L+TKPP  +T  +L+ AM NAA +VTD  LK+ L+E  GLGTEATR+G+++ L+ 
Sbjct  478  SEVRTLQTKPPAHYTEGTLLDAMKNAARFVTDPRLKQRLRETEGLGTEATRAGLIQGLID  537

Query  537  RNFISIKGRYLRATDIAMDLIDALPHALKEPGMTALWEQALDEVAKGRMTLDSFMSRQTQ  596
            + F+  K + L A+  A+ LID+LP+ LK+PG+TALWEQAL+++A G MTLD+FM +Q  
Sbjct  538  KGFLLKKKKSLVASAEAVALIDSLPDLLKNPGLTALWEQALNQIAEGSMTLDAFMQKQEA  597

Query  597  WICQLVSLGTQQDVVVRVPPTPACPLCGSKTRLRKGAKGAFYGCEKYPDCKGMINVPGQS  656
             + QL++   QQ++ +       C+ CG   R  + AKG+F GC  YPDC+   +   + 
Sbjct  598  FVKQLIGSCMQQGMSLGNIEIRKCSECGKPMRKINHAKGTFWGCTGYPDCQHK-EADKKV  656

Query  657  KNAASKTRKKKQN  669
            K+A++K+ KK  N
Sbjct  657  KSASNKSAKKSSN  669

> NC_016808_R1|63|G56|378773985|YP_005176228.1|Pasteurella_multocida_36950|-|54272..56323|topB1|Pmu_03290|DNA 
topoisomerase 
III
Length=683

 Score =  561 bits (2117),  Expect = 6e-161, Method: Compositional matrix adjust.
 Identities = 329/650 (51%), Positives = 475/650 (74%), Gaps = 6/650 (0%)

Query  1    MRVFLCEKPSQGKDIARVLGAGHRGNG--CYSGAGVVVTWCIGHLVEAVPPEGYGDQYKR  58
            M++F+CEKPSQ++D+A VLGA  +G+G    ++ +++VTW +GHLVE   PE+Y++  KR
Sbjct  1    MKLFICEKPSQARDLAGVLGATSKGEGLLATADKSIIVTWGFGHLVEQYQPEDYDEAWKR  60

Query  59   WAIEQLPILPERWRVEPKAATAAQFKVVQQLVAKAGELVIATDADREGEMIAREIIDLCG  118
            WA+E LPI+P +W++ PK  +  Q+ VV  L+ KA  +VIATDADREGEMIARE++DL G
Sbjct  61   WAFETLPIIPAQWKMTPKKESKKQYSVVIGLIKKATSVVIATDADREGEMIARELLDLAG  120

Query  119  YHGPIQRLWLSALNDASIRKALGALKPSAETLPLYFSALARSRADWLIGMNLSRLFTLLG  178
            Y+G IQR WLSAL+DASIRKAL +LK++ ET +LY+++++RSR+DWLIGMN+SRLFTL++
Sbjct  121  YRGQIQRCWLSALDDASIRKALQTLKSGKETEALYYAGMGRSRSDWLIGMNFSRLFTLMA  180

Query  179  RQAGYMG-VLSVGRVQTPTLKLVVDRDREIARFVSVPYWAVDV-LLSHAGRSFTASWIPP  236
            +  GY G  LSVGRVQ+PTL LVV+RDREIA FV+ +  A+ V L + +G +F A+   P
Sbjct  181  QAKGYSGKPLSVGRVQSPTLTLVVNRDREIANFVPKSHYALAVQLTTTSGETFVAGLAVP  240

Query  237  EGSTDAAGRCLQQPVAQQAADCIRAARDAQVVSVDTERVREAPPLPFDLGTLQEVCSKQL  296
            E   D +G CL+  V QQA   I+ +  A+VV+V+T R + +PPL + L+ LQ  C++ +
Sbjct  241  EQYLDESGLCLDSRVIQQAEAQIKQTGLAKVVTVETKREKKSPPLLYALSDLQGECNRLF  300

Query  297  GLDVQETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLDALLATDPSLRPLIGQL  356
            G++ Q+ LDIAQ+LYE HK TTYPR+D GYLPES +++VP V+ +L+A+D++L+ L+ +L
Sbjct  301  GFGAQQVLDIAQSLYEEHKITTYPRTDCGYLPESQFSDVPNVIRSLVASDSGLQTLLPKL  360

Query  357  DRNQRSRAWNDGKVTAHHGIIPTLEPANLSAMNEKELAVYRLIRAHYLAQFLPHHEFDRT  416
            +  Q+SRAW+D K+TAHHGIIPT+  A+LS ++E E+ VY LIR +YLAQFLPH E D+T
Sbjct  361  NLRQKSRAWDDKKITAHHGIIPTIKKADLSKLSEEEMKVYDLIRRRYLAQFLPHLEMDKT  420

Query  417  VAQFSCGSQSLAAVGKQIAVTGWREVLATPGPDDADGEDAQRSQVLPALHAGLSCPVGKV  476
            VA +  ++++L A G+ I   GWR +L     D+  G+D ++ Q LP L     C V   
Sbjct  421  VATLQSSGHTLVARGNVIVAQGWR-ILFGKNVDEETGNDDEK-QGLPVLTKNQQCNVTHS  478

Query  477  DLKALKTLPPKPYTQGELIKAMKTVAKFVTDPRLKQKLRDTTGIGTEATRANTINGLIGR  536
            ++++L+T PP  YT+G L+ AMK  A+FVTDPRLKQ+LR+T G+GTEATRA  I+GLI++
Sbjct  479  EVRTLQTKPPAHYTEGTLLDAMKNAARFVTDPRLKQRLRETEGLGTEATRAGLIQGLIDK  538

Query  537  GYLVKKGRAVRASDAAFTLIDAVPSAIADPGTTAVWEQALDMIEAGQMALDTFIEKQSVW  596
            G+L+KK +++ AS  A +LID++P  + +PG TA+WEQAL+ I  G M+LD+F++KQ   
Sbjct  539  GFLLKKKKSLVASAEAVALIDSLPDLLKNPGLTALWEQALNQIAEGSMTLDAFMQKQEAF  598

Query  597  VGQLVQQYRGATLSLKLppapacpqcgapmqqRTGKSGAFWSCSRYPDCK  646
            V QL+       +SL       C++CG PM++     G+FW+C+ YPDC+
Sbjct  599  VKQLIGSCMQQGMSLGNIEIRKCSECGKPMRKINHAKGTFWGCTGYPDCQ  648

> NC_016808_R1|63|G56|378773985|YP_005176228.1|Pasteurella_multocida_36950|-|54272..56323|topB1|Pmu_03290|DNA 
topoisomerase 
III
Length=683

 Score =  553 bits (2089),  Expect = 1e-158, Method: Compositional matrix adjust.
 Identities = 319/672 (48%), Positives = 471/672 (71%), Gaps = 7/672 (1%)

Query  1    MRLFLCEKPSQGRDIAAVLGATKRGTGFLQGP--GVTVTWAVGHLLETASPEAYGTQFAR  58
            M+LF+CEKPSQ+RD+A+VLGAT +G G+L  +  ++ VTW+ GHL+E   PE Y+    R
Sbjct  1    MKLFICEKPSQARDLAGVLGATSKGEGLLATADKSIIVTWGFGHLVEQYQPEDYDEAWKR  60

Query  59   PWNIHALPVLPAQWQMVVKKETEDQFKAIAKLLKQVDEVVIATDADREGEVIARELLDFC  118
             W +++LP++PAQW+M  KKE+  Q+  +  L+K+   VVIATDADREGE+IARELLD+ 
Sbjct  61   -WAFETLPIIPAQWKMTPKKESKKQYSVVIGLIKKATSVVIATDADREGEMIARELLDLA  119

Query  119  QWRGPVNRLWLSALDEPSIRNGLNNIKPGNETLALYYAGLGRARADWLTGMNLTRLYTLK  178
              RG ++R WLSALD++SIR++L+ +K+G+ET ALYYAG+GR+R+DWL GMN++RL+TL 
Sbjct  120  GYRGQIQRCWLSALDDASIRKALQTLKSGKETEALYYAGMGRSRSDWLIGMNFSRLFTLM  179

Query  179  AREKGFDG-VLSVGRVQTPTLALVVNRDREIAIFVPKPYWQVNAALQA-CGMAFVARWVP  236
            A+ KG+ G  LSVGRVQ+PTL+LVVNRDREIA FVPK+   +   L +  G +FVA    
Sbjct  180  AQAKGYSGKPLSVGRVQSPTLTLVVNRDREIANFVPKSHYALAVQLTTTSGETFVAGLAV  239

Query  237  AKMYTDEEKRCVHQGIAQQVAQLCRQSGQAQVIEQEKKRETEAAPLAFSLGALQQACGKL  296
            +  Y DE   C++  + QQ     +Q+G A+V+  E KRE  ++PL ++L+ LQ  C +L
Sbjct  240  PEQYLDESGLCLDSRVIQQAEAQIKQTGLAKVVTVETKREKKSPPLLYALSDLQGECNRL  299

Query  297  WDMSPQQVLDTAQSLYETHKATTYPRTDCGFLPESMREEIPLVLAALAKTDPSLTTTIAT  356
             + ++QQVLD AQSLYE HK TTYPRTDCG+LPES   ++P V+ +L  +D++L T ++ 
Sbjct  300  FGFGAQQVLDIAQSLYEEHKITTYPRTDCGYLPESQFSDVPNVIRSLVASDSGLQTLLPK  359

Query  357  LDPRFVSRIWNDKKITAHHGIIPTKHASDMGNMNDVEKRVYELIRRHYLAQFLPLYERDV  416
            L+ R  SR W+DKKITAHHGIIPT   +D++++++ E +VY+LIRR+YLAQFLP  E D 
Sbjct  360  LNLRQKSRAWDDKKITAHHGIIPTIKKADLSKLSEEEMKVYDLIRRRYLAQFLPHLEMDK  419

Query  417  TRLDLSIGGQLFRTTGQVVVVPGWKVLFSSATDRKGNAQGDEDNALPSLNKGDVCTVTVA  476
            T   L  +G+ + + G+V+V  GW++LF+   D    +++DE ++LP L K + C VT +
Sbjct  420  TVATLQSSGHTLVARGNVIVAQGWRILFGKNVD-EETGNDDEKQGLPVLTKNQQCNVTHS  478

Query  477  EVKDLKTKAPLYFTFDTLIAAMMNAASYVTDLQLKKVLKENAGLGTEATRASIIDTLLKR  536
            EV+ L+TK+P  +T +TL+ AM NAA +VTD +LK+ L+E  GLGTEATRA++I+ L+ +
Sbjct  479  EVRTLQTKPPAHYTEGTLLDAMKNAARFVTDPRLKQRLRETEGLGTEATRAGLIQGLIDK  538

Query  537  GYIVMNRRYLRATEVAMDLMDALPAPLKEPGMTALWEQALDEVAAGRMRLEDFMARQTGW  596
            G+++ +++ L A+  A+ L+D+LP  LK+PG+TALWEQAL+++A G M L+ FM +Q + 
Sbjct  539  GFLLKKKKSLVASAEAVALIDSLPDLLKNPGLTALWEQALNQIAEGSMTLDAFMQKQEAF  598

Query  597  TRQLVAQGLAQNMVIRLPPTPVCPLCGSKTRLRRGEKKAFYRCEKYPSCKGVVNVPDQVK  656
             +QL++  + Q M +       C+ CG   R     K +F  C  YP C+   +   +VK
Sbjct  599  VKQLIGSCMQQGMSLGNIEIRKCSECGKPMRKINHAKGTFWGCTGYPDCQH-KEADKKVK  657

Query  657  RKSAKSTSRKPK  668
              S KS+ + ++
Sbjct  658  SASNKSAKKSSN  669

> NC_016808_R1|63|G56|378773985|YP_005176228.1|Pasteurella_multocida_36950|-|54272..56323|topB1|Pmu_03290|DNA 
topoisomerase 
III
Length=683

 Score =  553 bits (2086),  Expect = 2e-158, Method: Compositional matrix adjust.
 Identities = 322/649 (50%), Positives = 463/649 (72%), Gaps = 6/649 (0%)

Query  1    MRLVLCEKPSQGRDIAKFLGATQRGEGFLNGP--GVTVTWARGHLLETAEPEVYGEQYGK  58
            M+L +CEKPSQ+RD+A  LGAT +GEG+L  +  ++ VTW+ GHL+E  +PE Y+E   K
Sbjct  1    MKLFICEKPSQARDLAGVLGATSKGEGLLATADKSIIVTWGFGHLVEQYQPEDYDEAW-K  59

Query  59   PWRTDVLPLLPQQWKLVVKADAKAQFAVINRLLKQVDEVVIATDADREGEVIARELLDYC  118
             W  + LP++P QWK+  K ++K Q++V+  L+K+   VVIATDADREGE+IARELLD  
Sbjct  60   RWAFETLPIIPAQWKMTPKKESKKQYSVVIGLIKKATSVVIATDADREGEMIARELLDLA  119

Query  119  KFQGRVFRLWMSALDDASIRSALADLWPSSRTESLYYAGVGRSRADWLIGMNLTRLFTLL  178
             ++G++ R W+SALDDASIR AL  L ++  TE+LYYAG+GRSR+DWLIGMN++RLFTL+
Sbjct  120  GYRGQIQRCWLSALDDASIRKALQTLKSGKETEALYYAGMGRSRSDWLIGMNFSRLFTLM  179

Query  179  GREAG-IGNVLSVGRVQTPTLAIVVKRDREIDNFVSKPYFEVIATMAV-NGVLFPSKWVP  236
            ++  G  G+ LSVGRVQ+PTL++VV+RDREI NFV+K+ + +   ++  +G  F +    
Sbjct  180  AQAKGYSGKPLSVGRVQSPTLTLVVNRDREIANFVPKSHYALAVQLTTTSGETFVAGLAV  239

Query  237  AAQYCDEEKRCIQSGVAAQVVQLCRQTPTAAIINCQIERKKQSAPLAFSLSTLQQACSRH  296
            + QY DE   C++S V  Q     +QT  A ++  +  R K+S+PL ++LS LQ  C+R 
Sbjct  240  PEQYLDESGLCLDSRVIQQAEAQIKQTGLAKVVTVETKREKKSPPLLYALSDLQGECNRL  299

Query  297  WGMPAQTVLDIAQKLYETHKLTTYPRTDCGYLPLSMREEIPQVLSAVVGTDPALQPVVAS  356
             G  AQ VLDIAQ LYE HK+TTYPRTDCGYLP S   ++P+V+ ++V++D++LQ +++ 
Sbjct  300  FGFGAQQVLDIAQSLYEEHKITTYPRTDCGYLPESQFSDVPNVIRSLVASDSGLQTLLPK  359

Query  357  LDTQFVSRIWNDKKITAHHGIIPTKHTGDLSKLSDAERNVYQLVRLHYLAQFLPQMEIDV  416
            L+ +  SR W+DKKITAHHGIIPT   +DLSKLS+ E +VY+L+R +YLAQFLP++E+D 
Sbjct  360  LNLRQKSRAWDDKKITAHHGIIPTIKKADLSKLSEEEMKVYDLIRRRYLAQFLPHLEMDK  419

Query  417  TEATFNIGGQLFRTRGNVLVKPGWKSLFGKMSEDDEDNTGET-TLPAMQAGQVCQVQGAE  475
            T AT++ +G+ + +RGNV+V  GW+ LFGK  +++ +N +E   LP +   Q C+V  +E
Sbjct  420  TVATLQSSGHTLVARGNVIVAQGWRILFGKNVDEETGNDDEKQGLPVLTKNQQCNVTHSE  479

Query  476  QKVLQTKPPAPYNDGTLIAAMTNAAAFVTDAALKKVLKENAGIGTEATRAGIIDTLLKRG  535
             + LQTKPPA Y +GTL+ AM NAA FVTD+ LK+ L+E  G+GTEATRAG+I+ L+ +G
Sbjct  480  VRTLQTKPPAHYTEGTLLDAMKNAARFVTDPRLKQRLRETEGLGTEATRAGLIQGLIDKG  539

Query  536  FLVREKKTLKSTPLGRNLVDVLPGTLTNPGLTALWEQMLDEVAAGRVSLDDFMAKQSQWV  595
            FL++ KK+L +++ +  L+D LP+ L NPGLTALWEQ L+++A G ++LD FM KQ   V
Sbjct  540  FLLKKKKSLVASAEAVALIDSLPDLLKNPGLTALWEQALNQIAEGSMTLDAFMQKQEAFV  599

Query  596  SQLVAQGRSQPLTMQAPPSPPCPVCGGKTLQRNGKSGLFWGCLKYPECK  644
             QL++    Q +++       C+ CG    + N   G FWGC  YP+C+
Sbjct  600  KQLIGSCMQQGMSLGNIEIRKCSECGKPMRKINHAKGTFWGCTGYPDCQ  648

> NC_016808_R1|63|G56|378773985|YP_005176228.1|Pasteurella_multocida_36950|-|54272..56323|topB1|Pmu_03290|DNA 
topoisomerase 
III
Length=683

 Score =  553 bits (2086),  Expect = 2e-158, Method: Compositional matrix adjust.
 Identities = 322/649 (50%), Positives = 463/649 (72%), Gaps = 6/649 (0%)

Query  1    MRLVLCEKPSQGRDIAKFLGATQRGEGFLNGP--GVTVTWARGHLLETAEPEVYGEQYGK  58
            M+L +CEKPSQ+RD+A  LGAT +GEG+L  +  ++ VTW+ GHL+E  +PE Y+E   K
Sbjct  1    MKLFICEKPSQARDLAGVLGATSKGEGLLATADKSIIVTWGFGHLVEQYQPEDYDEAW-K  59

Query  59   PWRTDVLPLLPQQWKLVVKADAKAQFAVINRLLKQVDEVVIATDADREGEVIARELLDYC  118
             W  + LP++P QWK+  K ++K Q++V+  L+K+   VVIATDADREGE+IARELLD  
Sbjct  60   RWAFETLPIIPAQWKMTPKKESKKQYSVVIGLIKKATSVVIATDADREGEMIARELLDLA  119

Query  119  KFQGRVFRLWMSALDDASIRSALADLWPSSRTESLYYAGVGRSRADWLIGMNLTRLFTLL  178
             ++G++ R W+SALDDASIR AL  L ++  TE+LYYAG+GRSR+DWLIGMN++RLFTL+
Sbjct  120  GYRGQIQRCWLSALDDASIRKALQTLKSGKETEALYYAGMGRSRSDWLIGMNFSRLFTLM  179

Query  179  GREAG-IGNVLSVGRVQTPTLAIVVKRDREIDNFVSKPYFEVIATMAV-NGVLFPSKWVP  236
            ++  G  G+ LSVGRVQ+PTL++VV+RDREI NFV+K+ + +   ++  +G  F +    
Sbjct  180  AQAKGYSGKPLSVGRVQSPTLTLVVNRDREIANFVPKSHYALAVQLTTTSGETFVAGLAV  239

Query  237  AAQYCDEEKRCIQSGVAAQVVQLCRQTPTAAIINCQIERKKQSAPLAFSLSTLQQACSRH  296
            + QY DE   C++S V  Q     +QT  A ++  +  R K+S+PL ++LS LQ  C+R 
Sbjct  240  PEQYLDESGLCLDSRVIQQAEAQIKQTGLAKVVTVETKREKKSPPLLYALSDLQGECNRL  299

Query  297  WGMPAQTVLDIAQKLYETHKLTTYPRTDCGYLPLSMREEIPQVLSAVVGTDPALQPVVAS  356
             G  AQ VLDIAQ LYE HK+TTYPRTDCGYLP S   ++P+V+ ++V++D++LQ +++ 
Sbjct  300  FGFGAQQVLDIAQSLYEEHKITTYPRTDCGYLPESQFSDVPNVIRSLVASDSGLQTLLPK  359

Query  357  LDTQFVSRIWNDKKITAHHGIIPTKHTGDLSKLSDAERNVYQLVRLHYLAQFLPQMEIDV  416
            L+ +  SR W+DKKITAHHGIIPT   +DLSKLS+ E +VY+L+R +YLAQFLP++E+D 
Sbjct  360  LNLRQKSRAWDDKKITAHHGIIPTIKKADLSKLSEEEMKVYDLIRRRYLAQFLPHLEMDK  419

Query  417  TEATFNIGGQLFRTRGNVLVKPGWKSLFGKMSEDDEDNTGET-TLPAMQAGQVCQVQGAE  475
            T AT++ +G+ + +RGNV+V  GW+ LFGK  +++ +N +E   LP +   Q C+V  +E
Sbjct  420  TVATLQSSGHTLVARGNVIVAQGWRILFGKNVDEETGNDDEKQGLPVLTKNQQCNVTHSE  479

Query  476  QKVLQTKPPAPYNDGTLIAAMTNAAAFVTDAALKKVLKENAGIGTEATRAGIIDTLLKRG  535
             + LQTKPPA Y +GTL+ AM NAA FVTD+ LK+ L+E  G+GTEATRAG+I+ L+ +G
Sbjct  480  VRTLQTKPPAHYTEGTLLDAMKNAARFVTDPRLKQRLRETEGLGTEATRAGLIQGLIDKG  539

Query  536  FLVREKKTLKSTPLGRNLVDVLPGTLTNPGLTALWEQMLDEVAAGRVSLDDFMAKQSQWV  595
            FL++ KK+L +++ +  L+D LP+ L NPGLTALWEQ L+++A G ++LD FM KQ   V
Sbjct  540  FLLKKKKSLVASAEAVALIDSLPDLLKNPGLTALWEQALNQIAEGSMTLDAFMQKQEAFV  599

Query  596  SQLVAQGRSQPLTMQAPPSPPCPVCGGKTLQRNGKSGLFWGCLKYPECK  644
             QL++    Q +++       C+ CG    + N   G FWGC  YP+C+
Sbjct  600  KQLIGSCMQQGMSLGNIEIRKCSECGKPMRKINHAKGTFWGCTGYPDCQ  648

> NC_016808_R1|63|G56|378773985|YP_005176228.1|Pasteurella_multocida_36950|-|54272..56323|topB1|Pmu_03290|DNA 
topoisomerase 
III
Length=683

 Score =  553 bits (2086),  Expect = 2e-158, Method: Compositional matrix adjust.
 Identities = 322/649 (50%), Positives = 463/649 (72%), Gaps = 6/649 (0%)

Query  1    MRLVLCEKPSQGRDIAKFLGATQRGEGFLNGP--GVTVTWARGHLLETAEPEVYGEQYGK  58
            M+L +CEKPSQ+RD+A  LGAT +GEG+L  +  ++ VTW+ GHL+E  +PE Y+E   K
Sbjct  1    MKLFICEKPSQARDLAGVLGATSKGEGLLATADKSIIVTWGFGHLVEQYQPEDYDEAW-K  59

Query  59   PWRTDVLPLLPQQWKLVVKADAKAQFAVINRLLKQVDEVVIATDADREGEVIARELLDYC  118
             W  + LP++P QWK+  K ++K Q++V+  L+K+   VVIATDADREGE+IARELLD  
Sbjct  60   RWAFETLPIIPAQWKMTPKKESKKQYSVVIGLIKKATSVVIATDADREGEMIARELLDLA  119

Query  119  KFQGRVFRLWMSALDDASIRSALADLWPSSRTESLYYAGVGRSRADWLIGMNLTRLFTLL  178
             ++G++ R W+SALDDASIR AL  L ++  TE+LYYAG+GRSR+DWLIGMN++RLFTL+
Sbjct  120  GYRGQIQRCWLSALDDASIRKALQTLKSGKETEALYYAGMGRSRSDWLIGMNFSRLFTLM  179

Query  179  GREAG-IGNVLSVGRVQTPTLAIVVKRDREIDNFVSKPYFEVIATMAV-NGVLFPSKWVP  236
            ++  G  G+ LSVGRVQ+PTL++VV+RDREI NFV+K+ + +   ++  +G  F +    
Sbjct  180  AQAKGYSGKPLSVGRVQSPTLTLVVNRDREIANFVPKSHYALAVQLTTTSGETFVAGLAV  239

Query  237  AAQYCDEEKRCIQSGVAAQVVQLCRQTPTAAIINCQIERKKQSAPLAFSLSTLQQACSRH  296
            + QY DE   C++S V  Q     +QT  A ++  +  R K+S+PL ++LS LQ  C+R 
Sbjct  240  PEQYLDESGLCLDSRVIQQAEAQIKQTGLAKVVTVETKREKKSPPLLYALSDLQGECNRL  299

Query  297  WGMPAQTVLDIAQKLYETHKLTTYPRTDCGYLPLSMREEIPQVLSAVVGTDPALQPVVAS  356
             G  AQ VLDIAQ LYE HK+TTYPRTDCGYLP S   ++P+V+ ++V++D++LQ +++ 
Sbjct  300  FGFGAQQVLDIAQSLYEEHKITTYPRTDCGYLPESQFSDVPNVIRSLVASDSGLQTLLPK  359

Query  357  LDTQFVSRIWNDKKITAHHGIIPTKHTGDLSKLSDAERNVYQLVRLHYLAQFLPQMEIDV  416
            L+ +  SR W+DKKITAHHGIIPT   +DLSKLS+ E +VY+L+R +YLAQFLP++E+D 
Sbjct  360  LNLRQKSRAWDDKKITAHHGIIPTIKKADLSKLSEEEMKVYDLIRRRYLAQFLPHLEMDK  419

Query  417  TEATFNIGGQLFRTRGNVLVKPGWKSLFGKMSEDDEDNTGET-TLPAMQAGQVCQVQGAE  475
            T AT++ +G+ + +RGNV+V  GW+ LFGK  +++ +N +E   LP +   Q C+V  +E
Sbjct  420  TVATLQSSGHTLVARGNVIVAQGWRILFGKNVDEETGNDDEKQGLPVLTKNQQCNVTHSE  479

Query  476  QKVLQTKPPAPYNDGTLIAAMTNAAAFVTDAALKKVLKENAGIGTEATRAGIIDTLLKRG  535
             + LQTKPPA Y +GTL+ AM NAA FVTD+ LK+ L+E  G+GTEATRAG+I+ L+ +G
Sbjct  480  VRTLQTKPPAHYTEGTLLDAMKNAARFVTDPRLKQRLRETEGLGTEATRAGLIQGLIDKG  539

Query  536  FLVREKKTLKSTPLGRNLVDVLPGTLTNPGLTALWEQMLDEVAAGRVSLDDFMAKQSQWV  595
            FL++ KK+L +++ +  L+D LP+ L NPGLTALWEQ L+++A G ++LD FM KQ   V
Sbjct  540  FLLKKKKSLVASAEAVALIDSLPDLLKNPGLTALWEQALNQIAEGSMTLDAFMQKQEAFV  599

Query  596  SQLVAQGRSQPLTMQAPPSPPCPVCGGKTLQRNGKSGLFWGCLKYPECK  644
             QL++    Q +++       C+ CG    + N   G FWGC  YP+C+
Sbjct  600  KQLIGSCMQQGMSLGNIEIRKCSECGKPMRKINHAKGTFWGCTGYPDCQ  648

> NC_016808_R1|63|G56|378773985|YP_005176228.1|Pasteurella_multocida_36950|-|54272..56323|topB1|Pmu_03290|DNA 
topoisomerase 
III
Length=683

 Score =  553 bits (2086),  Expect = 2e-158, Method: Compositional matrix adjust.
 Identities = 322/649 (50%), Positives = 463/649 (72%), Gaps = 6/649 (0%)

Query  1    MRLVLCEKPSQGRDIAKFLGATQRGEGFLNGP--GVTVTWARGHLLETAEPEVYGEQYGK  58
            M+L +CEKPSQ+RD+A  LGAT +GEG+L  +  ++ VTW+ GHL+E  +PE Y+E   K
Sbjct  1    MKLFICEKPSQARDLAGVLGATSKGEGLLATADKSIIVTWGFGHLVEQYQPEDYDEAW-K  59

Query  59   PWRTDVLPLLPQQWKLVVKADAKAQFAVINRLLKQVDEVVIATDADREGEVIARELLDYC  118
             W  + LP++P QWK+  K ++K Q++V+  L+K+   VVIATDADREGE+IARELLD  
Sbjct  60   RWAFETLPIIPAQWKMTPKKESKKQYSVVIGLIKKATSVVIATDADREGEMIARELLDLA  119

Query  119  KFQGRVFRLWMSALDDASIRSALADLWPSSRTESLYYAGVGRSRADWLIGMNLTRLFTLL  178
             ++G++ R W+SALDDASIR AL  L ++  TE+LYYAG+GRSR+DWLIGMN++RLFTL+
Sbjct  120  GYRGQIQRCWLSALDDASIRKALQTLKSGKETEALYYAGMGRSRSDWLIGMNFSRLFTLM  179

Query  179  GREAG-IGNVLSVGRVQTPTLAIVVKRDREIDNFVSKPYFEVIATMAV-NGVLFPSKWVP  236
            ++  G  G+ LSVGRVQ+PTL++VV+RDREI NFV+K+ + +   ++  +G  F +    
Sbjct  180  AQAKGYSGKPLSVGRVQSPTLTLVVNRDREIANFVPKSHYALAVQLTTTSGETFVAGLAV  239

Query  237  AAQYCDEEKRCIQSGVAAQVVQLCRQTPTAAIINCQIERKKQSAPLAFSLSTLQQACSRH  296
            + QY DE   C++S V  Q     +QT  A ++  +  R K+S+PL ++LS LQ  C+R 
Sbjct  240  PEQYLDESGLCLDSRVIQQAEAQIKQTGLAKVVTVETKREKKSPPLLYALSDLQGECNRL  299

Query  297  WGMPAQTVLDIAQKLYETHKLTTYPRTDCGYLPLSMREEIPQVLSAVVGTDPALQPVVAS  356
             G  AQ VLDIAQ LYE HK+TTYPRTDCGYLP S   ++P+V+ ++V++D++LQ +++ 
Sbjct  300  FGFGAQQVLDIAQSLYEEHKITTYPRTDCGYLPESQFSDVPNVIRSLVASDSGLQTLLPK  359

Query  357  LDTQFVSRIWNDKKITAHHGIIPTKHTGDLSKLSDAERNVYQLVRLHYLAQFLPQMEIDV  416
            L+ +  SR W+DKKITAHHGIIPT   +DLSKLS+ E +VY+L+R +YLAQFLP++E+D 
Sbjct  360  LNLRQKSRAWDDKKITAHHGIIPTIKKADLSKLSEEEMKVYDLIRRRYLAQFLPHLEMDK  419

Query  417  TEATFNIGGQLFRTRGNVLVKPGWKSLFGKMSEDDEDNTGET-TLPAMQAGQVCQVQGAE  475
            T AT++ +G+ + +RGNV+V  GW+ LFGK  +++ +N +E   LP +   Q C+V  +E
Sbjct  420  TVATLQSSGHTLVARGNVIVAQGWRILFGKNVDEETGNDDEKQGLPVLTKNQQCNVTHSE  479

Query  476  QKVLQTKPPAPYNDGTLIAAMTNAAAFVTDAALKKVLKENAGIGTEATRAGIIDTLLKRG  535
             + LQTKPPA Y +GTL+ AM NAA FVTD+ LK+ L+E  G+GTEATRAG+I+ L+ +G
Sbjct  480  VRTLQTKPPAHYTEGTLLDAMKNAARFVTDPRLKQRLRETEGLGTEATRAGLIQGLIDKG  539

Query  536  FLVREKKTLKSTPLGRNLVDVLPGTLTNPGLTALWEQMLDEVAAGRVSLDDFMAKQSQWV  595
            FL++ KK+L +++ +  L+D LP+ L NPGLTALWEQ L+++A G ++LD FM KQ   V
Sbjct  540  FLLKKKKSLVASAEAVALIDSLPDLLKNPGLTALWEQALNQIAEGSMTLDAFMQKQEAFV  599

Query  596  SQLVAQGRSQPLTMQAPPSPPCPVCGGKTLQRNGKSGLFWGCLKYPECK  644
             QL++    Q +++       C+ CG    + N   G FWGC  YP+C+
Sbjct  600  KQLIGSCMQQGMSLGNIEIRKCSECGKPMRKINHAKGTFWGCTGYPDCQ  648

> NC_016808_R1|63|G56|378773985|YP_005176228.1|Pasteurella_multocida_36950|-|54272..56323|topB1|Pmu_03290|DNA 
topoisomerase 
III
Length=683

 Score =  552 bits (2085),  Expect = 2e-158, Method: Compositional matrix adjust.
 Identities = 321/649 (50%), Positives = 462/649 (72%), Gaps = 6/649 (0%)

Query  1    MRLVLCEKPSQGRDIAKFLGATQRGEGFLNGP--GVTVTWARGHLLETAEPEVYGEQYGK  58
            M+L +CEKPSQ+RD+A  LGAT +GEG+L  +  ++ VTW+ GHL+E  +PE Y+E   K
Sbjct  1    MKLFICEKPSQARDLAGVLGATSKGEGLLATADKSIIVTWGFGHLVEQYQPEDYDEAW-K  59

Query  59   PWRTDVLPLLPQQWKLVVKADAKAQFAVINRLLKQVDEVVIATDADREGEVIARELLDYC  118
             W  + LP++P QWK+  K ++K Q++V+  L+K+   VVIATDADREGE+IARELLD  
Sbjct  60   RWAFETLPIIPAQWKMTPKKESKKQYSVVIGLIKKATSVVIATDADREGEMIARELLDLA  119

Query  119  KFQGRVFRLWMSALDDASIRSALADLWPSSRTESLYYAGVGRSRADWLIGMNLTRLFTLL  178
             ++G++ R W+SALDDASIR AL  L ++  TE+LYYAG+GRSR+DWLIGMN++RLFTL+
Sbjct  120  GYRGQIQRCWLSALDDASIRKALQTLKSGKETEALYYAGMGRSRSDWLIGMNFSRLFTLM  179

Query  179  GREAG-IGNVLSVGRVQTPTLAIVVKRDREIDNFVSKPYFEVIATMAV-NGVLFPSKWVP  236
            ++  G  G+ LSVGRVQ+PTL++VV+RDREI NFV+K+ + +   ++  +G  F +    
Sbjct  180  AQAKGYSGKPLSVGRVQSPTLTLVVNRDREIANFVPKSHYALAVQLTTTSGETFVAGLAV  239

Query  237  AAQYCDEEKRCIQSGVAAQVVQLCRQTPTAAIINCQIERKKQSAPLAFSLSTLQQACSRH  296
            + QY DE   C++S V  Q     +QT  A ++  +  R K+S+PL ++LS LQ  C+R 
Sbjct  240  PEQYLDESGLCLDSRVIQQAEAQIKQTGLAKVVTVETKREKKSPPLLYALSDLQGECNRL  299

Query  297  WGMPAQTVLDIAQKLYETHKLTTYPRTDCGYLPLSMREEIPQVLSAVVGTDPALQPVVAS  356
             G  AQ VLDIAQ LYE HK+TTYPRTDCGYLP S   ++P+V+ ++V++D++LQ +++ 
Sbjct  300  FGFGAQQVLDIAQSLYEEHKITTYPRTDCGYLPESQFSDVPNVIRSLVASDSGLQTLLPK  359

Query  357  LDTQFVSRIWNDKKITAHHGIIPTKHTGDLSKLSDAERNVYQLVRLHYLAQFLPQMEIDV  416
            L+ +  SR W+DKKITAHHGIIPT   +DLSKLS+ E +VY+L+R +YLAQFLP++E+D 
Sbjct  360  LNLRQKSRAWDDKKITAHHGIIPTIKKADLSKLSEEEMKVYDLIRRRYLAQFLPHLEMDK  419

Query  417  TEVTFNIGGQLFRTRGNVLVKPGWKSLFGKMSEDDEDNTGET-TLPAMQAGQVCQVQGAE  475
            T  T++ +G+ + +RGNV+V  GW+ LFGK  +++ +N +E   LP +   Q C+V  +E
Sbjct  420  TVATLQSSGHTLVARGNVIVAQGWRILFGKNVDEETGNDDEKQGLPVLTKNQQCNVTHSE  479

Query  476  QKVLQTKPPAPYNDGTLIAAMTNAAAFVTDAALKKVLKENAGIGTEATRAGIIDTLLKRG  535
             + LQTKPPA Y +GTL+ AM NAA FVTD+ LK+ L+E  G+GTEATRAG+I+ L+ +G
Sbjct  480  VRTLQTKPPAHYTEGTLLDAMKNAARFVTDPRLKQRLRETEGLGTEATRAGLIQGLIDKG  539

Query  536  FLVREKKTLKSTPLGRNLVDVLPGTLTNPGLTALWEQMLDEVAAGRVSLDDFMAKQSQWV  595
            FL++ KK+L +++ +  L+D LP+ L NPGLTALWEQ L+++A G ++LD FM KQ   V
Sbjct  540  FLLKKKKSLVASAEAVALIDSLPDLLKNPGLTALWEQALNQIAEGSMTLDAFMQKQEAFV  599

Query  596  SQLVAQGRSQPLTMQAPPSPPCPVCGGKTLQRNGKSGLFWGCLKYPECK  644
             QL++    Q +++       C+ CG    + N   G FWGC  YP+C+
Sbjct  600  KQLIGSCMQQGMSLGNIEIRKCSECGKPMRKINHAKGTFWGCTGYPDCQ  648

> NC_016808_R1|63|G56|378773985|YP_005176228.1|Pasteurella_multocida_36950|-|54272..56323|topB1|Pmu_03290|DNA 
topoisomerase 
III
Length=683

 Score =  552 bits (2082),  Expect = 4e-158, Method: Compositional matrix adjust.
 Identities = 330/650 (51%), Positives = 478/650 (74%), Gaps = 6/650 (0%)

Query  1    MRVFLCEKPSQGKDIARVLGAVQRGNG--CYSGAGVVVTWCIGHLVEAVPPEGYGEQYKR  58
            M++F+CEKPSQ++D+A VLGA  +G+G    ++ +++VTW +GHLVE   PE+Y+E  KR
Sbjct  1    MKLFICEKPSQARDLAGVLGATSKGEGLLATADKSIIVTWGFGHLVEQYQPEDYDEAWKR  60

Query  59   WAIEQLPILPERWRVEPKAATAAQFKVVQQLVAKAGELVIATDADREGEMIAREIIDLCG  118
            WA+E LPI+P +W++ PK  +  Q+ VV  L+ KA  +VIATDADREGEMIARE++DL G
Sbjct  61   WAFETLPIIPAQWKMTPKKESKKQYSVVIGLIKKATSVVIATDADREGEMIARELLDLAG  120

Query  119  YRGPIQRLWLSALNDASIRKALGALKPSAETLPLYFSALARSRADWLIGMNLSRLFTLLG  178
            YRG IQR WLSAL+DASIRKAL +LK++ ET +LY+++++RSR+DWLIGMN+SRLFTL++
Sbjct  121  YRGQIQRCWLSALDDASIRKALQTLKSGKETEALYYAGMGRSRSDWLIGMNFSRLFTLMA  180

Query  179  RQAGYTG-VLSVGRVQTPTLKLVVDRDREIARFVSMPYWAVDV-LLSHAGQSFTASWIPP  236
            +  GY+G  LSVGRVQ+PTL LVV+RDREIA FV+ +  A+ V L + +G++F A+   P
Sbjct  181  QAKGYSGKPLSVGRVQSPTLTLVVNRDREIANFVPKSHYALAVQLTTTSGETFVAGLAVP  240

Query  237  EGSTDAAGRCLQQPvaqqaadriraardaqvvSVDTERVREAPPLPFDLGTLQEVCSKQL  296
            E   D +G CL+  V QQA  +I+ +  A+VV+V+T R + +PPL + L+ LQ  C++ +
Sbjct  241  EQYLDESGLCLDSRVIQQAEAQIKQTGLAKVVTVETKREKKSPPLLYALSDLQGECNRLF  300

Query  297  GLDVQETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPTVLDSLVKTDPSLRPLIERL  356
            G++ Q+ LDIAQ+LYE HK TTYPR+D GYLPES +++VP V+ SLV +D++L+ L+ +L
Sbjct  301  GFGAQQVLDIAQSLYEEHKITTYPRTDCGYLPESQFSDVPNVIRSLVASDSGLQTLLPKL  360

Query  357  DRQQRSRAWNDGKVSAHHGIIPTLEPANLSAMNEKELAVYRLICAHYLAQFLPHHEFDRT  416
            + +Q+SRAW+D K++AHHGIIPT+  A+LS ++E E+ VY LI  +YLAQFLPH E D+T
Sbjct  361  NLRQKSRAWDDKKITAHHGIIPTIKKADLSKLSEEEMKVYDLIRRRYLAQFLPHLEMDKT  420

Query  417  VAQFSCGSQSLAAVGKQIAVTGWREVLATPGPDDADGEDAQRSQVLPALHAGLSCPVGKV  476
            VA +  ++++L A G+ I   GWR +L     D+  G+D ++ Q LP L     C V   
Sbjct  421  VATLQSSGHTLVARGNVIVAQGWR-ILFGKNVDEETGNDDEK-QGLPVLTKNQQCNVTHS  478

Query  477  DLKALKTLPPKPYTQGELIKAMKTVAKFVTDPRLKQKLRDTTGIGTEATRANIINGLIGR  536
            ++++L+T PP  YT+G L+ AMK  A+FVTDPRLKQ+LR+T G+GTEATRA +I+GLI++
Sbjct  479  EVRTLQTKPPAHYTEGTLLDAMKNAARFVTDPRLKQRLRETEGLGTEATRAGLIQGLIDK  538

Query  537  GYLVKKGRAVRASDAAFTLIDAVPSAIADPGTTAVWEQALDMIEAGQMALDTFIEKQSVW  596
            G+L+KK +++ AS  A +LID++P  + +PG TA+WEQAL+ I  G M+LD+F++KQ   
Sbjct  539  GFLLKKKKSLVASAEAVALIDSLPDLLKNPGLTALWEQALNQIAEGSMTLDAFMQKQEAF  598

Query  597  VGQLVQQYRGATLSLKLppapacpqcgapmqqRTGKSGAFWSCSRYPDCK  646
            V QL+       +SL       C++CG PM++     G+FW+C+ YPDC+
Sbjct  599  VKQLIGSCMQQGMSLGNIEIRKCSECGKPMRKINHAKGTFWGCTGYPDCQ  648

> NC_016808_R1|63|G56|378773985|YP_005176228.1|Pasteurella_multocida_36950|-|54272..56323|topB1|Pmu_03290|DNA 
topoisomerase 
III
Length=683

 Score =  548 bits (2070),  Expect = 3e-157, Method: Compositional matrix adjust.
 Identities = 327/653 (51%), Positives = 467/653 (72%), Gaps = 9/653 (1%)

Query  1    MQLYLCEKPSQGKDIGAILGATQRKQGYLAGA--GVIVTWAIGHLLEQAQPETYGEQFGS  58
            M+L++CEKPSQ++D++++LGAT + +G LA A  ++IVTW++GHL+EQ QPE Y+E    
Sbjct  1    MKLFICEKPSQARDLAGVLGATSKGEGLLATADKSIIVTWGFGHLVEQYQPEDYDEAW-K  59

Query  59   PWRESVLPIVPTQWKMTVKKETADQFAVIRGLLKQVDSVVIATDADREGEVIARELLEHC  118
             W    LPI+P+QWKMT KKE+  Q++V+ GL+K+  SVVIATDADREGE+IARELL+  
Sbjct  60   RWAFETLPIIPAQWKMTPKKESKKQYSVVIGLIKKATSVVIATDADREGEMIARELLDLA  119

Query  119  HFTGPVQRLWLSALDEASIRHALANKLPGEKTAPLYEAGLARSRADWMTGMNLTRLYTLK  178
             + G +QR WLSALD+ASIR AL    +G  T +LY AG++RSR+DW+ GMN++RL+TL 
Sbjct  120  GYRGQIQRCWLSALDDASIRKALQTLKSGKETEALYYAGMGRSRSDWLIGMNFSRLFTLM  179

Query  179  AREQGY-GEVLSIGRVQTPTLALVVNRDRDIANFISKPYWQVRATLQK-GGIAFPASWVP  236
            A+ +GY G  LS+GRVQ+PTL+LVVNRDR+IANF++K+   +   L   +G +F A+   
Sbjct  180  AQAKGYSGKPLSVGRVQSPTLTLVVNRDREIANFVPKSHYALAVQLTTTSGETFVAGLAV  239

Query  237  AANYCDEEKRCIQQNVAQAVVQLCQQTGHAVVLEVGTERKKESAPLAFDLGTLQQACSRK  296
            + +Y DE   C++  V Q      +QTG A V+ V T R K S+PL + L+ LQ  C+R 
Sbjct  240  PEQYLDESGLCLDSRVIQQAEAQIKQTGLAKVVTVETKREKKSPPLLYALSDLQGECNRL  299

Query  297  WGMSANQALSIAQSLYETHKATTYPRTDCGYLPTSMREEVADVLSAVTRTDPTQSGSVAR  356
             G +A+Q L IAQSLYE HK TTYPRTDCGYLP S   +V++V+ ++  +D+     +++
Sbjct  300  FGFGAQQVLDIAQSLYEEHKITTYPRTDCGYLPESQFSDVPNVIRSLVASDSGLQTLLPK  359

Query  357  LDRTFVSRIWNDKKITAHHGIIPTKQPFDLSKLSADELKVYQLIRQHYLAQFLPLHEVDV  416
            L+    SR W+DKKITAHHGIIPT +  DLSKLS +E+KVY+LIR++YLAQFLP  E+D 
Sbjct  360  LNLRQKSRAWDDKKITAHHGIIPTIKKADLSKLSEEEMKVYDLIRRRYLAQFLPHLEMDK  419

Query  417  TEATFNIGGQLFRTRGKVEVVAGWKVLFQHDVSEAKEESTDTDDVRLPALVKGETVAVAG  476
            T AT++ +G+ + +RG+V V  GW++LF  +V E   +  + ++  LP L K +   V+ 
Sbjct  420  TVATLQSSGHTLVARGNVIVAQGWRILFGKNVDEETGNDDEKQG--LPVLTKNQQCNVTH  477

Query  477  AELKTLQTKPPGHFTDGTLIAAMKNAAAFVSDPQLKKVLKENAGLGTEATRAGILETLFK  536
            +E++TLQTKPP+H+T+GTL+ AMKNAA FV+DP+LK+ L+E  GLGTEATRAG+++ L+ 
Sbjct  478  SEVRTLQTKPPAHYTEGTLLDAMKNAARFVTDPRLKQRLRETEGLGTEATRAGLIQGLID  537

Query  537  RGYLEKKGKYLLSTPIAGELIDALPTALTNPGMTALWEQALDEIAQGQMTLDTFMSRQAQ  596
            +G+L KK K L++++ A  LID+LP  L NPG+TALWEQAL++IA+G MTLD+FM +Q  
Sbjct  538  KGFLLKKKKSLVASAEAVALIDSLPDLLKNPGLTALWEQALNQIAEGSMTLDAFMQKQEA  597

Query  597  WTGHLVEKGKAQAVKFtappsppcptcsGTMRRRAGKKGSGAFWGCSNYPTCQ  649
               +L+     Q++ +       C+ C+  MR+   + + G+FWGC+ YP CQ
Sbjct  598  FVKQLIGSCMQQGMSLGNIEIRKCSECGKPMRKI--NHAKGTFWGCTGYPDCQ  648

> NC_016808_R1|63|G56|378773985|YP_005176228.1|Pasteurella_multocida_36950|-|54272..56323|topB1|Pmu_03290|DNA 
topoisomerase 
III
Length=683

 Score =  548 bits (2067),  Expect = 6e-157, Method: Compositional matrix adjust.
 Identities = 324/679 (48%), Positives = 471/679 (70%), Gaps = 12/679 (1%)

Query  1    MKLFLCEKPSQGRDIAVVLGATKRGQGYLTGP--GVTVTWAVGHLLETASPEVYGEQYGA  58
            MKLF+CEKPSQ+RD+A VLGAT +G+G L+ +  ++ VTW+ GHL+E   PE Y+E    
Sbjct  1    MKLFICEKPSQARDLAGVLGATSKGEGLLATADKSIIVTWGFGHLVEQYQPEDYDEAW-K  59

Query  59   PWRASVLPILPASWQMVVKKETADQFTVICRLLKQADEVVIATDADREGEVIARELLDYC  118
             W    LPI+PA W+M  KKE+  Q++V+  L+K+A  VVIATDADREGE+IARELLD  
Sbjct  60   RWAFETLPIIPAQWKMTPKKESKKQYSVVIGLIKKATSVVIATDADREGEMIARELLDLA  119

Query  119  QFQGKISRLWLSALDEVSIRAALANILPGEQTASLYLAGLGRARADWLIGMNFTRLYTVK  178
             ++G+I R WLSALD+ SIR AL  + +G +T +LY AG+GR+R+DWLIGMNF+RL+T+ 
Sbjct  120  GYRGQIQRCWLSALDDASIRKALQTLKSGKETEALYYAGMGRSRSDWLIGMNFSRLFTLM  179

Query  179  ARECGYSDI-LSIGRVQTPSLALVVFRDREIIAFTAKPYWQVVADLQF-DGRIFRADWVP  236
            A+  GYS+  LS+GRVQ+P+L+LVV RDREI  F +K+   +  +L    G  F A+   
Sbjct  180  AQAKGYSGKPLSVGRVQSPTLTLVVNRDREIANFVPKSHYALAVQLTTTSGETFVAGLAV  239

Query  237  AATYCDEEKRCIHQNVAQTVVKLCQQTGTATVLEINTKREKHAAPLAFDLGSLQQLCSKK  296
            +  Y DE   C++  V Q      +QTG A V+ ++TKREK ++PL + L+ LQ  C++ 
Sbjct  240  PEQYLDESGLCLDSRVIQQAEAQIKQTGLAKVVTVETKREKKSPPLLYALSDLQGECNRL  299

Query  297  WSMGAQQVLNIAQNLYETHKATTYPRTDCGYLPTAMQAEIPQVLDAVVKSDPAMRIVVDS  356
             + GAQQVL+IAQ+LYE HK TTYPRTDCGYLP +  +++P+V+ ++V SD++++ ++  
Sbjct  300  FGFGAQQVLDIAQSLYEEHKITTYPRTDCGYLPESQFSDVPNVIRSLVASDSGLQTLLPK  359

Query  357  LDRTLISRIWNDKKITAHHGIIPTKQPCDMNKMTDDERKVYQLIRQHYLLQFLPLHEMDI  416
            L+    SR W+DKKITAHHGIIPT +  D++K++++E KVY+LIR++YL QFLP  EMD 
Sbjct  360  LNLRQKSRAWDDKKITAHHGIIPTIKKADLSKLSEEEMKVYDLIRRRYLAQFLPHLEMDK  419

Query  417  TEATFDIGGQLFRTRGNVVIVPGWKVLFSAGKDESASIGKDDSLGESLPSMVKGNQCQVN  476
            T AT++ +G+ + +RGNV++  GW++LF  GK+     G+DD   ++LP + K +QC+V 
Sbjct  420  TVATLQSSGHTLVARGNVIVAQGWRILF--GKNVDEETGNDDE-KQGLPVLTKNQQCNVT  476

Query  477  EATLRMLQTQPSAHFTEGTLIAAMKNAAAFVSDPQLKKVLKDNAGLGTEATRAGVLDTLF  536
            ++ +R LQT+P+AH+TEGTL+ AMKNAA FV+DP+LK+ L++  GLGTEATRAG+++ L+
Sbjct  477  HSEVRTLQTKPPAHYTEGTLLDAMKNAARFVTDPRLKQRLRETEGLGTEATRAGLIQGLI  536

Query  537  KRGYLTKKGKYIHATQIASELIAALPTALTNPGLTALWEQALDDIAQGQAELPDFMARQV  596
             +G+L KK K + A+  A  LI +LP  L NPGLTALWEQAL++IA+G   L  FM +Q 
Sbjct  537  DKGFLLKKKKSLVASAEAVALIDSLPDLLKNPGLTALWEQALNQIAEGSMTLDAFMQKQE  596

Query  597  QWTQYLVEQVQAQKVVITPPPSLPCPVCGGVTRQRQGKNGVFWGCIKYPECSGVVSTVDG  656
               + L+     Q + +       C+ CG   R+ +  +G FWGC  YP+C       ++
Sbjct  597  AFVKQLIGSCMQQGMSLGNIEIRKCSECGKPMRKINHAKGTFWGCTGYPDC----QHKEA  652

Query  657  KRKTRSARHKNIPKKPAMT  675
             +K +SA +K+  K + + 
Sbjct  653  DKKVKSASNKSAKKSSNLN  671

> NC_016808_R1|63|G56|378773985|YP_005176228.1|Pasteurella_multocida_36950|-|54272..56323|topB1|Pmu_03290|DNA 
topoisomerase 
III
Length=683

 Score =  545 bits (2058),  Expect = 3e-156, Method: Compositional matrix adjust.
 Identities = 326/677 (49%), Positives = 481/677 (72%), Gaps = 10/677 (1%)

Query  1    MRLFLCEKPSQGKDIARVLGAKQRGDGCFH--GDAITVTWCIGHLVEAAEPDAYGEQYKS  58
            M+LF+CEKPSQ++D+A VLGA  +G+G +   + +I VTW +GHLVE  +P+ Y+E  K 
Sbjct  1    MKLFICEKPSQARDLAGVLGATSKGEGLLATADKSIIVTWGFGHLVEQYQPEDYDEAWKR  60

Query  59   WSIDQLPIIPDPWRIEIKPKTAAQLKIVKALIAQADELVIATDADREGEMIARELLELFS  118
            W+++ LPIIP  W++  K  +  Q  +V +LI +A  +VIATDADREGEMIARELL+L +
Sbjct  61   WAFETLPIIPAQWKMTPKKESKKQYSVVIGLIKKATSVVIATDADREGEMIARELLDLAG  120

Query  119  YRGPIQRLWLSALNDASIRQALGALRPGSETLPLYHAALARSRADWLVGMNLSRLFTVLG  178
            YRG IQR WLSAL+DASIR+AL +L++G ET +LY A+++RSR+DWL+GMN+SRLFT+++
Sbjct  121  YRGQIQRCWLSALDDASIRKALQTLKSGKETEALYYAGMGRSRSDWLIGMNFSRLFTLMA  180

Query  179  RQAGYDG-VLSVGRVQTPTLRLVVDRDREIARFVSVPFWTIELALSS-NGQRFTAHWQAP  236
            +  GY G  LSVGRVQ+PTL LVV+RDREIA FV+ +  ++ + L++ +G+ F A    P
Sbjct  181  QAKGYSGKPLSVGRVQSPTLTLVVNRDREIANFVPKSHYALAVQLTTTSGETFVAGLAVP  240

Query  237  DGSTDDAGRCLQQPVAQSALATLQNARDVEVMSVDTERMREAPPLPFDLGTLQETCSRQL  296
            +   D++G CL+  V Q A A ++++    V++V+T R + +PPL + L+ LQ  C+R +
Sbjct  241  EQYLDESGLCLDSRVIQQAEAQIKQTGLAKVVTVETKREKKSPPLLYALSDLQGECNRLF  300

Query  297  GLDVQETLDIAQALYETHKATTYPRTDCGYLPESMLADVPTILTALVRTDPSLLPLIATL  356
            G++ Q+ LDIAQ+LYE HK TTYPRTDCGYLPES ++DVP ++ +LV +D++L  L++ L
Sbjct  301  GFGAQQVLDIAQSLYEEHKITTYPRTDCGYLPESQFSDVPNVIRSLVASDSGLQTLLPKL  360

Query  357  DPTQRSRAWNDGKITAHHGIIPTLEPANLAAMSDKEQAVYRLIRAHYLAQFLPHHEFDRT  416
            +  Q+SRAW+D KITAHHGIIPT+  A+L+ +S+ E  VY LIR +YLAQFLPH E D+T
Sbjct  361  NLRQKSRAWDDKKITAHHGIIPTIKKADLSKLSEEEMKVYDLIRRRYLAQFLPHLEMDKT  420

Query  417  VAQFASGPERLTATGKQIAVIGWHSVLNEPASNEDTGDDSESPRSQTLPPLENGTRCAME  476
            VA + S+ + L A G+ I   GW+ +L     +E+TG+D E    Q LP L +  +C + 
Sbjct  421  VATLQSSGHTLVARGNVIVAQGWR-ILFGKNVDEETGNDDE---KQGLPVLTKNQQCNVT  476

Query  477  QVELKALTTQPPRPYTQGELIKAMKGVAKLVSDPRLKQILKDTTGIGTEATRASIIQGLI  536
            + E+++L T+PP  YT+G L+ AMK  A++V+DPRLKQ L++T G+GTEATRA++IQGLI
Sbjct  477  HSEVRTLQTKPPAHYTEGTLLDAMKNAARFVTDPRLKQRLRETEGLGTEATRAGLIQGLI  536

Query  537  ARGYLLKKGRAVRGSDAAFTLidaipaaiadpgttaiWEQALERIEAGDMTLDAFVTRQA  596
             +G+LLKK +++ +S  A +LID++P  + +PG TA+WEQAL++I  G MTLDAF+ +Q 
Sbjct  537  DKGFLLKKKKSLVASAEAVALIDSLPDLLKNPGLTALWEQALNQIAEGSMTLDAFMQKQE  596

Query  597  TWVTQLVQHYAQTTLAIKlppsppcplcgsTMRQRTSQRGPFWSCTRYPDCKGTLPVEKS  656
            + V QL+    Q  +++       C+ CG  MR+    +G FW+CT YPDC+        
Sbjct  597  AFVKQLIGSCMQQGMSLGNIEIRKCSECGKPMRKINHAKGTFWGCTGYPDCQHK--EADK  654

Query  657  KTKRRAADTPRRGHSFG  673
            K K  +  +++++ ++ 
Sbjct  655  KVKSASNKSAKKSSNLN  671

> NC_016808_R1|63|G56|378773985|YP_005176228.1|Pasteurella_multocida_36950|-|54272..56323|topB1|Pmu_03290|DNA 
topoisomerase 
III
Length=683

 Score =  543 bits (2049),  Expect = 2e-155, Method: Compositional matrix adjust.
 Identities = 316/650 (49%), Positives = 476/650 (74%), Gaps = 6/650 (0%)

Query  1    MRLFLCEKPSQGKDIGRLLGARQRGNGCLNGP--GVVVTWCIGHLVEAAPPEAYDEQLKR  58
            M+LF+CEKPSQ++D++ +LGA  +G+G L  +  +++VTW +GHLVE   PE YDE  KR
Sbjct  1    MKLFICEKPSQARDLAGVLGATSKGEGLLATADKSIIVTWGFGHLVEQYQPEDYDEAWKR  60

Query  59   WTIEQLPIIPQHWRVEVKPKTAAQFKVVKDLLSKATELVIATDADREGELIAREIIDLCG  118
            W++E LPIIP +W++  K  +  Q+ VV +L+ KAT +VIATDADREGE+IARE++DL G
Sbjct  61   WAFETLPIIPAQWKMTPKKESKKQYSVVIGLIKKATSVVIATDADREGEMIARELLDLAG  120

Query  119  YRGPIQRLWLSALNDASIHAALGKLKPSGDTLPMYHSALARSRADWLVGMNLSRLFTLLG  178
            YRG IQR WLSAL+DASI+ AL  LK++ +T ++Y ++++RSR+DWL+GMN+SRLFTL++
Sbjct  121  YRGQIQRCWLSALDDASIRKALQTLKSGKETEALYYAGMGRSRSDWLIGMNFSRLFTLMA  180

Query  179  RRAGYDG-VLSVGRVQTPTLRLVVDRDREIAAFVSVPFWSIEVALSCT-GQTFTAQWLPP  236
            +  GY G  LSVGRVQ+PTL LVV+RDREIA FV+ +  ++ V L+ T G+TF A    P
Sbjct  181  QAKGYSGKPLSVGRVQSPTLTLVVNRDREIANFVPKSHYALAVQLTTTSGETFVAGLAVP  240

Query  237  SASTDDAGRCLQEPvaqqavqriraagaaqMVSVETERMREGAPLPFDLGTLQEVCSKQF  296
                D++G CL+  V QQA  +I+ +G A++V+VET R + ++PL + L+ LQ  C++ F
Sbjct  241  EQYLDESGLCLDSRVIQQAEAQIKQTGLAKVVTVETKREKKSPPLLYALSDLQGECNRLF  300

Query  297  GLDVQETLEIAQSLYETHKATTYPRSDSGYLPESMHAEAPTVLDSLLKTDPSLRPIIDQL  356
            G++ Q+ L+IAQSLYE HK TTYPR+D GYLPES  ++ P V+ SL+ +D++L+ ++ +L
Sbjct  301  GFGAQQVLDIAQSLYEEHKITTYPRTDCGYLPESQFSDVPNVIRSLVASDSGLQTLLPKL  360

Query  357  DRTQHSRAWNDAKVSAHHGIIPTLEPANLSAMSEKELAAYRLIRAHYLAQFLPPHEFDRT  416
            +  Q SRAW+D K++AHHGIIPT+  A+LS +SE E+  Y LIR +YLAQFLP  E D+T
Sbjct  361  NLRQKSRAWDDKKITAHHGIIPTIKKADLSKLSEEEMKVYDLIRRRYLAQFLPHLEMDKT  420

Query  417  TARFSCGDQTLQAVGKHVVVPGWRLVLaepqpddagddaapRSQVLPALHQGLACQVAGV  476
             A +  +++TL A G+ +V  GWR++++    +++G+D     Q LP L +   C+V+  
Sbjct  421  VATLQSSGHTLVARGNVIVAQGWRILFGKNVDEETGNDDE--KQGLPVLTKNQQCNVTHS  478

Query  477  DLKALKTLPPRPYTQGELVKAMKSVAKLVSDPRLKQKLKDSVGIGTEATRANIIGGLLNR  536
            ++++L+T PP  YT+G L+ AMK+ A++V+DPRLKQ+L+++ G+GTEATRA +I GL+++
Sbjct  479  EVRTLQTKPPAHYTEGTLLDAMKNAARFVTDPRLKQRLRETEGLGTEATRAGLIQGLIDK  538

Query  537  GYLIKKGRAIRASDAAFTLIDTVPAAIADPGTTAVWEQALDMIETGQLALDTFIDKQAAW  596
            G+L+KK +++ AS  A +LID++P  + +PG TA+WEQAL+ I  G ++LD+F++KQ A 
Sbjct  539  GFLLKKKKSLVASAEAVALIDSLPDLLKNPGLTALWEQALNQIAEGSMTLDAFMQKQEAF  598

Query  597  VTQLIAQYRGTSLSIKIPEGPACPQCGGATRQRSGKSGPFWSCAKYPDCK  646
            V QLI+     ++S+   E   C++CG + R+ +   G FW+C+ YPDC+
Sbjct  599  VKQLIGSCMQQGMSLGNIEIRKCSECGKPMRKINHAKGTFWGCTGYPDCQ  648

> NC_016808_R1|63|G56|378773985|YP_005176228.1|Pasteurella_multocida_36950|-|54272..56323|topB1|Pmu_03290|DNA 
topoisomerase 
III
Length=683

 Score =  543 bits (2049),  Expect = 2e-155, Method: Compositional matrix adjust.
 Identities = 319/678 (48%), Positives = 472/678 (70%), Gaps = 14/678 (2%)

Query  1    MRVVLCEKPSQGKDIARVLGAHRREAGCLGGP--GITVTWGSGHLIEAAPPEAYGEHFQR  58
            M++ +CEKPSQ++D+A VLGA  +  G L+ +  +I VTWG GHL+E   PE Y+E  +R
Sbjct  1    MKLFICEKPSQARDLAGVLGATSKGEGLLATADKSIIVTWGFGHLVEQYQPEDYDEAWKR  60

Query  59   WTLETLPIVPPRWQWVVKARSAAQFKVVKRLLGEASELIIATDADREGEMIAREMIDYCG  118
            W++ETLPI+P++W+   K  S  Q+ VV  L+  A+ ++IATDADREGEMIARE++D  G
Sbjct  61   WAFETLPIIPAQWKMTPKKESKKQYSVVIGLIKKATSVVIATDADREGEMIARELLDLAG  120

Query  119  YRGPVQRLWLSALNDASIRKAFGALRASSETLSLYHCALARSRADWLVGINLTRLFTLLG  178
            YRG +QR WLSAL+DASIRKA+ +L+++ ET +LY  +++RSR+DWL+G+N++RLFTL++
Sbjct  121  YRGQIQRCWLSALDDASIRKALQTLKSGKETEALYYAGMGRSRSDWLIGMNFSRLFTLMA  180

Query  179  RHAGHDG-VLSVGRVQTPTLKLVVDRDREIAAFVPVPFWSIDVSLSAANV-PFSAHWLAP  236
            +  G  G  LSVGRVQ+PTL LVV+RDREIA FVP +  ++ V L++++   F A    P
Sbjct  181  QAKGYSGKPLSVGRVQSPTLTLVVNRDREIANFVPKSHYALAVQLTTTSGETFVAGLAVP  240

Query  237  RTATDDAGRCLRQSVarhaadairaagtaQVVHTETERVREGPPLPFDLSTLQEVCSRRL  296
                D++G CL   V ++A   I+ +G A+VV  ET R + +PPL + LS LQ  C+R +
Sbjct  241  EQYLDESGLCLDSRVIQQAEAQIKQTGLAKVVTVETKREKKSPPLLYALSDLQGECNRLF  300

Query  297  GLEVQETLDIAQALYETHKATTYPRTDAGYLPENMLAEVPTVIQSLVKTDPALQPLIDRL  356
            G+  Q+ LDIAQ+LYE HK TTYPRTD GYLPE+ +++VP VI+SLV +D++LQ L+ +L
Sbjct  301  GFGAQQVLDIAQSLYEEHKITTYPRTDCGYLPESQFSDVPNVIRSLVASDSGLQTLLPKL  360

Query  357  DFRQRSRAWNDAKITAHHAIIPTLEPADISAMSAKELAVYRLIRAHYLAQFLPHHEFDRT  416
            ++RQ+SRAW+D KITAHH+IIPT+  AD+S +S  E+ VY LIR +YLAQFLPH E D+T
Sbjct  361  NLRQKSRAWDDKKITAHHGIIPTIKKADLSKLSEEEMKVYDLIRRRYLAQFLPHLEMDKT  420

Query  417  VVRFRCGGETLQAVGKRIAVPGWQHAFSAPSLPHVAADGADTEGSDEAPREQMLPVLQEG  476
            V  ++ +G+TL A G+ I   GW+  F         +   D E +++  ++  LPVL   
Sbjct  421  VATLQSSGHTLVARGNVIVAQGWRILF---------GKNVDEETGNDDEKQG-LPVLTKN  470

Query  477  ISCQVSALDLKSLSTKPPRPYTQGELVKAMKTVARLVTDPRLKQKLKDTTGIGTEATRAN  536
              C+V+  ++++L TKPP  YT+G L+ AMK  AR+VTDPRLKQ+L++T G+GTEATRA 
Sbjct  471  QQCNVTHSEVRTLQTKPPAHYTEGTLLDAMKNAARFVTDPRLKQRLRETEGLGTEATRAG  530

Query  537  IISGLLSRGFLIRKGRAVRASDTAMMLIDAVPAAIADPGTTAIWEQALDMIEARQMGLES  596
            +I GL+ +GFL++K +++ AS  A+ LID++P  + +PG TA+WEQAL+ I    M L++
Sbjct  531  LIQGLIDKGFLLKKKKSLVASAEAVALIDSLPDLLKNPGLTALWEQALNQIAEGSMTLDA  590

Query  597  FVEKQAAWVTQLVRQHLGTTLAIRSPEGPPCPLCGAATRQRTGRSGPFWSCSRYPDCKGT  656
            F++KQ A V QL+   +   +++ + E   C+ CG + R+     G FW+C+ YPDC+  
Sbjct  591  FMQKQEAFVKQLIGSCMQQGMSLGNIEIRKCSECGKPMRKINHAKGTFWGCTGYPDCQHK  650

Query  657  APVAPAQAGPDGQKRSRS  674
             +    +++++   +  S
Sbjct  651  EADKKVKSASNKSAKKSS  668

> NC_016808_R1|63|G56|378773985|YP_005176228.1|Pasteurella_multocida_36950|-|54272..56323|topB1|Pmu_03290|DNA 
topoisomerase 
III
Length=683

 Score =  542 bits (2047),  Expect = 2e-155, Method: Compositional matrix adjust.
 Identities = 319/649 (50%), Positives = 456/649 (71%), Gaps = 5/649 (0%)

Query  1    MRLFICEKPSQGRDLANVLGATRRGDGFLTGP--GVTVTWAVGHLLETAPPEAYGQQYGK  58
            M+LFICEKPSQ+RDLA VLGAT +G+G+L+ +  ++ VTW+ GHL+E   PE Y++   K
Sbjct  1    MKLFICEKPSQARDLAGVLGATSKGEGLLATADKSIIVTWGFGHLVEQYQPEDYDEAW-K  59

Query  59   PWSLSALPILPSPWQVVVKKETKSQFKVIERLLRQVDDVVISTDADREGEVIARELLEYC  118
             W++ +LPI+P+ W++  KKE+K Q+ V+  L+++   VVI+TDADREGE+IARELL+  
Sbjct  60   RWAFETLPIIPAQWKMTPKKESKKQYSVVIGLIKKATSVVIATDADREGEMIARELLDLA  119

Query  119  RWDGPVQRLWLSALDEMSIRAALQDLRPGAETLGMYHAGLGRARADWLIGMNLSRLYTLL  178
               G +QR WLSALD+ SIR ALQ L++G ET ++Y AG+GR+R+DWLIGMN+SRL+TL+
Sbjct  120  GYRGQIQRCWLSALDDASIRKALQTLKSGKETEALYYAGMGRSRSDWLIGMNFSRLFTLM  179

Query  179  AVQSGFDG-VISVGRVQTPTLALVVRRDREIATFVPKPFWQVKA-LLSAGGRTFPAQWVP  236
            A   G+ G  +SVGRVQ+PTL+LVV RDREIA FVPK+   +   L +++G TF A    
Sbjct  180  AQAKGYSGKPLSVGRVQSPTLTLVVNRDREIANFVPKSHYALAVQLTTTSGETFVAGLAV  239

Query  237  AKVYTDEEKRCVHQNIAQQVAHLCRQAGAATVTECETKREKAAAPLAFSLGTLQQACGLL  296
            +  Y DE   C++  + QQ     +Q+G A V   ETKREK ++PL ++L+ LQ  C  L
Sbjct  240  PEQYLDESGLCLDSRVIQQAEAQIKQTGLAKVVTVETKREKKSPPLLYALSDLQGECNRL  299

Query  297  WDMSPQQVLDTAQSLYEKHKATTYPRTDCGYLPESMREEIPSVLSAIGLSDPECSSLLSG  356
             + ++QQVLD AQSLYE HK TTYPRTDCGYLPES   ++P+V+ ++  SD+   +LL+ 
Sbjct  300  FGFGAQQVLDIAQSLYEEHKITTYPRTDCGYLPESQFSDVPNVIRSLVASDSGLQTLLPK  359

Query  357  LNTSFVSRIWNDKKITAHHGIIPTRNAFKFSALSEAERRVYTLIRRNYLAQFLPLHESDI  416
            LN    SR W+DKKITAHHGIIPT +   +S LSE E +VY LIRR YLAQFLP  E D 
Sbjct  360  LNLRQKSRAWDDKKITAHHGIIPTIKKADLSKLSEEEMKVYDLIRRRYLAQFLPHLEMDK  419

Query  417  TRLQFDIGGQLFRTTGRTEIVMGWKVLFSKEEEDSAGDDDLSIELPPLRQGDRCGVNGAE  476
            T   ++ +G+ + + G   +  GW++LF+K+ ++ +G+DD    LP L + ++C V  +E
Sbjct  420  TVATLQSSGHTLVARGNVIVAQGWRILFGKNVDEETGNDDEKQGLPVLTKNQQCNVTHSE  479

Query  477  VVQQMTRPPAHYTFATLIGAMMNASAFVTDIALRKVLKDNAGLGTEATRAGIVEQLLNRR  536
            V    T+PPAHYT +TL++AM NA+ FVTD  L++ L++  GLGTEATRAG+++ L+++ 
Sbjct  480  VRTLQTKPPAHYTEGTLLDAMKNAARFVTDPRLKQRLRETEGLGTEATRAGLIQGLIDKG  539

Query  537  FIVRKGKQLRATDLGADVIDALPSQLTDPGMTALWEQALDEVAEGRLTLNDFLQRQVGWT  596
            F+++K K L A+  +  +ID+LP  L +PG+TALWEQAL+++AEG +TL+ F+Q+Q +  
Sbjct  540  FLLKKKKSLVASAEAVALIDSLPDLLKNPGLTALWEQALNQIAEGSMTLDAFMQKQEAFV  599

Query  597  RNLVSMGGQQRVSIRIPPTPSCPLCGGKTRLKKGQKGEFWGCTRYPDCK  645
            ++L++   QQ +S+       C+ CG   R  +  KG FWGCT YPDC+
Sbjct  600  KQLIGSCMQQGMSLGNIEIRKCSECGKPMRKINHAKGTFWGCTGYPDCQ  648