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PAthogenisity Island DataBase (PAI DB)

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Homologs of afaD gene of AF072900

protein-level

Hit (GenBank Accn)

Product

Source Genome

Eval.

Ident.(%)

1) O3M_26192
( YP_006772796.1 )

Protein Agg3B, putative invasin

NC_018654
(Escherichia coli 2009EL-2050)

9e-25

2) O3K_26202
( YP_006792566.1 )

Protein Agg3B, putative invasin

NC_018666
(Escherichia coli 2011C-3493)

9e-25

3) O3O_26292
( YP_006786920.1 )

Protein Agg3B, putative invasin

NC_018662
(Escherichia coli 2009EL-2071)

4e-21

4) aafB
( YP_006099161.1 )

afimbrial adhesin

NC_017627
(Escherichia coli 042)

3e-20

• Sequence Alignments

1) O3M_26192 in NC_018654


> AF072900|5|G5|5523844|AAD44023.1|Escherichia_coli_AL862|+|4823..5242|afaD|-|AfaD
Length=139

 Score =  106 bits (384),  Expect = 9e-25, Method: Compositional matrix adjust.
 Identities = 57/139 (42%), Positives = 97/139 (70%), Gaps = 2/139 (1%)

Query  3    KKSILPMSCGVLVMVMSGLLDAAEITLISHKTLESQLRDGMKLATGRIACREPHNGFYIW  62
             K I  +  G++++V+S+L +A E++L +     ++L+DG K+ATGRI CR    +F IW
Sbjct  1    MKKIQIVCSGIVLVVISSLAQAVELSLNTSDGRSGELKDGTKVATGRIICRGTYTSFHIW  60

Query  63   INASQNGKV-GHYIVQNNRETKHELKVKIGGGGWSSSLREGQRGVYRQGEEKQAIFDIMS  121
            +N+ Q G++ GHYI+   +++ +E++V+++G+GW +S+ +GQ G+   G   Q  FD++ 
Sbjct  61   MNSRQMGNIPGHYIILGRHDSHNEMRVRLDGAGWLPSVSDGQ-GMVSTGIPEQHTFDVVI  119

Query  122  DGNQYSAPGEYIFSVSGEC  140
            DGNQ  +P+EYI+SVSGEC
Sbjct  120  DGNQLLGPDEYILSVSGEC  138

2) O3K_26202 in NC_018666


> AF072900|5|G5|5523844|AAD44023.1|Escherichia_coli_AL862|+|4823..5242|afaD|-|AfaD
Length=139

 Score =  106 bits (384),  Expect = 9e-25, Method: Compositional matrix adjust.
 Identities = 57/139 (42%), Positives = 97/139 (70%), Gaps = 2/139 (1%)

Query  3    KKSILPMSCGVLVMVMSGLLDAAEITLISHKTLESQLRDGMKLATGRIACREPHNGFYIW  62
             K I  +  G++++V+S+L +A E++L +     ++L+DG K+ATGRI CR    +F IW
Sbjct  1    MKKIQIVCSGIVLVVISSLAQAVELSLNTSDGRSGELKDGTKVATGRIICRGTYTSFHIW  60

Query  63   INASQNGKV-GHYIVQNNRETKHELKVKIGGGGWSSSLREGQRGVYRQGEEKQAIFDIMS  121
            +N+ Q G++ GHYI+   +++ +E++V+++G+GW +S+ +GQ G+   G   Q  FD++ 
Sbjct  61   MNSRQMGNIPGHYIILGRHDSHNEMRVRLDGAGWLPSVSDGQ-GMVSTGIPEQHTFDVVI  119

Query  122  DGNQYSAPGEYIFSVSGEC  140
            DGNQ  +P+EYI+SVSGEC
Sbjct  120  DGNQLLGPDEYILSVSGEC  138

3) O3O_26292 in NC_018662


> AF072900|5|G5|5523844|AAD44023.1|Escherichia_coli_AL862|+|4823..5242|afaD|-|AfaD
Length=139

 Score = 94.4 bits (339),  Expect = 4e-21, Method: Compositional matrix adjust.
 Identities = 56/139 (41%), Positives = 96/139 (70%), Gaps = 2/139 (1%)

Query  3    KKSILPMSCGVLVMVMSGLLDAAEITLISHKTLESQLRDGMKLATGRIACREPHNGFYIW  62
             K I  +  G++++V+S+L +A E++L +     ++L+DG K+ATGRI CR    +F IW
Sbjct  1    MKKIQIVCSGIVLVVISSLAQAVELSLNTSDGRSGELKDGTKVATGRIICRGTYTSFHIW  60

Query  63   INASQNGKV-GHYIVQNNRETKHELKVKIgggggsssLREGQRGVYRQGEEKQAIFDIMS  121
            +N+ Q G++ GHYI+   +++ +E++V+++G+G  +S+ +GQ G+   G   Q  FD++ 
Sbjct  61   MNSRQMGNIPGHYIILGRHDSHNEMRVRLDGAGWLPSVSDGQ-GMVSTGIPEQHTFDVVI  119

Query  122  DGNQYSAPGEYIFSVSGEC  140
            DGNQ  +P+EYI+SVSGEC
Sbjct  120  DGNQLLGPDEYILSVSGEC  138

4) aafB in NC_017627


> AF072900|5|G5|5523844|AAD44023.1|Escherichia_coli_AL862|+|4823..5242|afaD|-|AfaD
Length=139

 Score = 91.2 bits (327),  Expect = 3e-20, Method: Compositional matrix adjust.
 Identities = 72/142 (51%), Positives = 102/142 (72%), Gaps = 5/142 (3%)

Query  1    MKKGMLSVSC-GMLLMVISGLSQATEISLEGLHRNMGEQLFDGDILATGRIICRERHTGF  59
            MKK  + + C G++L+VIS+L+QA E+SL+  +   GE L DG  +ATGRIICR   T+F
Sbjct  1    MKK--IQIVCSGIVLVVISSLAQAVELSLNTSDGRSGE-LKDGTKVATGRIICRGTYTSF  57

Query  60   HIQMNARQVEGRPGHYIVQGSKDTQSKLWVRLggegwtsptgggQQGIVRSGQEEQVIFD  119
            HI MN+RQ+   PGHYI+ G  D+++ ++VRL+G GW ++ ++G QG+V +G  EQ  FD
Sbjct  58   HIWMNSRQMGNIPGHYIILGRHDSHNEMRVRLDGAGWLPSVSDG-QGMVSTGIPEQHTFD  116

Query  120  VMADGNQWAKPGEYIFSVSGKC  141
            V+ DGNQ   P+EYI+SVSG C
Sbjct  117  VVIDGNQLLGPDEYILSVSGEC  138