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PAthogenisity Island DataBase (PAI DB)

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Homologs of hsdS gene of NC_007168_R1

protein-level

Hit (GenBank Accn)

Product

Source Genome

Eval.

Ident.(%)

1) hsdS
( YP_251978.1 )

hypothetical protein

NC_007168
(Staphylococcus haemolyticus JCSC1435)

2e-177

100

2) Amico_0450
( YP_003553315.1 )

restriction modification system DNA specificity domain-containing protein

NC_014011
(Aminobacterium colombiense DSM 12261)

8e-61

3) DCF50_p1410
( YP_006913401.1 )

Type I restriction-modification system, specificity subunit S

NC_018867
(Dehalobacter sp. CF)

1e-57

• Sequence Alignments

1) hsdS in NC_007168


> NC_007168_R1|41|G41|70725064|YP_251978.1|Staphylococcus_haemolyticus_JCSC1435|-|42252..43475|hsdS|SH0063|hypothetical 
protein
Length=407

 Score =  615 bits (2324),  Expect = 2e-177, Method: Compositional matrix adjust.
 Identities = 407/407 (100%), Positives = 407/407 (100%), Gaps = 0/407 (0%)

Query  1    MEYKLEKLLDSVSIKHPFSKKNVVFLNTSDIEEGNILKKEYSKIDDLPGQAKKSIQPNDI  60
            MEYKLEKLLDSVSIKHPFSKKNVVFLNTSDIEEGNILKKEYSKIDDLPGQAKKSIQPNDI
Sbjct  1    MEYKLEKLLDSVSIKHPFSKKNVVFLNTSDIEEGNILKKEYSKIDDLPGQAKKSIQPNDI  60

Query  61   LYSEIRPKNKRYAYINFECDDYVVSTKLMVLRNINPDLVHSKYLYYFLIDQKTVNYLQNI  120
            LYSEIRPKNKRYAYINFECDDYVVSTKLMVLRNINPDLVHSKYLYYFLIDQKTVNYLQNI
Sbjct  61   LYSEIRPKNKRYAYINFECDDYVVSTKLMVLRNINPDLVHSKYLYYFLIDQKTVNYLQNI  120

Query  121  AESRSGTFPQITFSEVKNLKLDLPSIEKQITIINIMDTlnekinnnkkiisnleeLSQTS  180
            AESRSGTFPQITFSEVKNLKLDLPSIEKQITIINIMDTLNEKINNNKKIISNLEELSQTS
Sbjct  121  AESRSGTFPQITFSEVKNLKLDLPSIEKQITIINIMDTLNEKINNNKKIISNLEELSQTS  180

Query  181  FKRWFVDFEFPDEDGNPYKSSGGEMIDSELGEIPKNWSIKTVKEIAESFNSIRKPLSKIE  240
            FKRWFVDFEFPDEDGNPYKSSGGEMIDSELGEIPKNWSIKTVKEIAESFNSIRKPLSKIE
Sbjct  181  FKRWFVDFEFPDEDGNPYKSSGGEMIDSELGEIPKNWSIKTVKEIAESFNSIRKPLSKIE  240

Query  241  REKRESIYPYYGATKIIDYVDNYIFDGKYILVGEDGTVQTETGNPFIQYVWGKFWVSNHA  300
            REKRESIYPYYGATKIIDYVDNYIFDGKYILVGEDGTVQTETGNPFIQYVWGKFWVSNHA
Sbjct  241  REKRESIYPYYGATKIIDYVDNYIFDGKYILVGEDGTVQTETGNPFIQYVWGKFWVSNHA  300

Query  301  HILKGKLISDELLMLYLKNTNVAPYITGAVQPKLNKKNLNSIKFVIADKETIIKFENSIK  360
            HILKGKLISDELLMLYLKNTNVAPYITGAVQPKLNKKNLNSIKFVIADKETIIKFENSIK
Sbjct  301  HILKGKLISDELLMLYLKNTNVAPYITGAVQPKLNKKNLNSIKFVIADKETIIKFENSIK  360

Query  361  SYFQKIRILNKENKKLIELRDTLLPKLMSGEIEIPDDIEVNIDELSI  407
            SYFQKIRILNKENKKLIELRDTLLPKLMSGEIEIPDDIEVNIDELSI
Sbjct  361  SYFQKIRILNKENKKLIELRDTLLPKLMSGEIEIPDDIEVNIDELSI  407

2) Amico_0450 in NC_014011


> NC_007168_R1|41|G41|70725064|YP_251978.1|Staphylococcus_haemolyticus_JCSC1435|-|42252..43475|hsdS|SH0063|hypothetical 
protein
Length=407

 Score =  227 bits (847),  Expect = 8e-61, Method: Compositional matrix adjust.
 Identities = 141/295 (48%), Positives = 201/295 (69%), Gaps = 15/295 (5%)

Query  103  YLFYLL--KHNVKNLKKTESG--TVFGGVNKKDIMGLSVMWTPNLQEQKTIAATLSCLDD  158
            YL+Y+L  +  V+ L++   +    F  +   ++  L +   P+++ Q TI   +  L++
Sbjct  103  YLYYFLIDQKTVNYLQNIAESRSGTFPQITFSEVKNLKLDL-PSIEKQITIINIMDTLNE  161

Query  159  KIELNNRINKTLEEMAQAIFKSWFVDFE-------PFQN--GEFIDSELGKIPKGWRVGT  209
            KI+ N++I   LEE++Q+ FK WFVDFE       P+++  GE IDSELG IPK W + T
Sbjct  162  KINNNKKIISNLEELSQTSFKRWFVDFEFPDEDGNPYKSSGGEMIDSELGEIPKNWSIKT  221

Query  210  LDEIIELFDSKRIPLSSRKREKMQKVYPYYGATSLMDYVDDYIFDGVYVLLGEDGTVIDG  269
            + EI E F+S R PLS   REK + +YPYYGAT ++DYVD+YIFDG Y+L+GEDGTV   
Sbjct  222  VKEIAESFNSIRKPLSKIEREKRESIYPYYGATKIIDYVDNYIFDGKYILVGEDGTVQTE  281

Query  270  KGYPILQYVWGKFWVNNHAHVLKGKNGFSEESLYILLKNTNVKSIVTGAVQLKINQSNLK  329
             G P++QYVWGKFWV+NHAH+LKGK  +S+E L + LKNTNV + +TGAVQ K+N+ NL+
Sbjct  282  TGNPFIQYVWGKFWVSNHAHILKGKL-ISDELLMLYLKNTNVAPYITGAVQPKLNKKNLN  340

Query  330  SVKVIIPSVDKIAEFNYLIARFFAEKRRLSEENQILISVRDALLPKLMSGEVRVP  384
            S+K +I+  + I  F+  I  +F   R L+ EN+ LI +RD+LLPKLMSGE+ +P
Sbjct  341  SIKFVIADKETIIKFENSIKSYFQKIRILNKENKKLIELRDTLLPKLMSGEIEIP  395

3) DCF50_p1410 in NC_018867


> NC_007168_R1|41|G41|70725064|YP_251978.1|Staphylococcus_haemolyticus_JCSC1435|-|42252..43475|hsdS|SH0063|hypothetical 
protein
Length=407

 Score =  217 bits (807),  Expect = 1e-57, Method: Compositional matrix adjust.
 Identities = 145/314 (47%), Positives = 213/314 (68%), Gaps = 16/314 (5%)

Query  98   NNGLIRLR-INNQVADYTYIYYNL---RCNNYWGHIEAISGGTSTQPNMRINALLDYKIL  153
            +  L+ LR IN ++ +  Y+YY L   +  NY  +I    +GT   P++ ++ + + K+ 
Sbjct  85   STKLMVLRNINPDLVHSKYLYYFLIDQKTVNYLQNIAESRSGTF--PQITFSEVKNLKLD  142

Query  154  VPPIPQQKAIASILSALDEKIELNNRINKNLEEMAQAIFKSWFVDFE-------PFQ--D  204
            +P+I +Q +I +I+ +L+EKI+ N++I  NLEE++Q+ FK WFVDFE       P++  +
Sbjct  143  LPSIEKQITIINIMDTLNEKINNNKKIISNLEELSQTSFKRWFVDFEFPDEDGNPYKSSG  202

Query  205  GEFEDSELGRIPKGWRVGYLGEIIELYDSKRIPLSSRQREGLDKKYPYYGATSIMDYVDK  264
            GE  DSELG IPK W +  + EI E ++S R PLS  +RE  +  YPYYGAT I+DYVD+
Sbjct  203  GEMIDSELGEIPKNWSIKTVKEIAESFNSIRKPLSKIEREKRESIYPYYGATKIIDYVDN  262

Query  265  YIFDGIYLLLGEDGSVIDENEYPFLQYVWGKFWVNNHAHVIKGKNGFSEEYLFTLLKKTN  324
            YIFDG Y+L+GEDG+V  E   PF+QYVWGKFWV+NHAH++KGK  +S+E L   LK+TN
Sbjct  263  YIFDGKYILVGEDGTVQTETGNPFIQYVWGKFWVSNHAHILKGKL-ISDELLMLYLKNTN  321

Query  325  VRSIITGAVQLKINQGNLCNLRVLIPESNVVEKVNLILKDIFTMYRKNIEESRSLIETRD  384
            V + ITGAVQ K+N+ NL +++ +I++ + + K +  +K  F   R    E++ LIE RD
Sbjct  322  VAPYITGAVQPKLNKKNLNSIKFVIADKETIIKFENSIKSYFQKIRILNKENKKLIELRD  381

Query  385  SLLPKLMSGEIRVP  398
            +LLPKLMSGEI +P
Sbjct  382  TLLPKLMSGEIEIP  395