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Homologs of SERP2216 gene of NC_002976_P3

protein-level

Hit (GenBank Accn)

Product

Source Genome

Eval.

Ident.(%)

1) SERP2216
( YP_189772.1 )

ribokinase

NC_002976
(Staphylococcus epidermidis RP62A)

4e-142

100

2) C248_0030
( YP_006708792.1 )

kinase

NC_018608
(Staphylococcus aureus 08BA02176)

4e-130

3) Lreu_0159
( YP_001270768.1 )

ribokinase-like domain-containing protein

NC_009513
(Lactobacillus reuteri DSM 20016)

2e-50

4) LAR_0152
( YP_001841148.1 )

sugar kinase

NC_010609
(Lactobacillus reuteri JCM 1112)

2e-50

5) LVIS_2233
( YP_796314.1 )

ribokinase family sugar kinase

NC_008497
(Lactobacillus brevis ATCC 367)

8e-41

• Sequence Alignments

1) SERP2216 in NC_002976


> NC_002976_P3|4|G4|57865611|YP_189772.1|Staphylococcus_epidermidis_RP62A|-|1235..2173|-|SERP2216|ribokinase
Length=312

 Score =  497 bits (1874),  Expect = 4e-142, Method: Compositional matrix adjust.
 Identities = 312/312 (100%), Positives = 312/312 (100%), Gaps = 0/312 (0%)

Query  1    MKNSSREYHQINSQKKVLVIGSAVIDVILNVNSIPSSGSDEFAHSEKTIVGGCAYNVGDI  60
            MKNSSREYHQINSQKKVLVIGSAVIDVILNVNSIPSSGSDEFAHSEKTIVGGCAYNVGDI
Sbjct  1    MKNSSREYHQINSQKKVLVIGSAVIDVILNVNSIPSSGSDEFAHSEKTIVGGCAYNVGDI  60

Query  61   LSQFKANYDLMVPVGDGLNGTIIENKLKKEGKTSLLNNILGDNGWTLCIVENNGERTFLT  120
            LSQFKANYDLMVPVGDGLNGTIIENKLKKEGKTSLLNNILGDNGWTLCIVENNGERTFLT
Sbjct  61   LSQFKANYDLMVPVGDGLNGTIIENKLKKEGKTSLLNNILGDNGWTLCIVENNGERTFLT  120

Query  121  IPGVEMTWKKNWFKEIDLNKYDYIYVSGYSFEPPSDEVLLEEFSRLNEKTTIIFDPSPRI  180
            IPGVEMTWKKNWFKEIDLNKYDYIYVSGYSFEPPSDEVLLEEFSRLNEKTTIIFDPSPRI
Sbjct  121  IPGVEMTWKKNWFKEIDLNKYDYIYVSGYSFEPPSDEVLLEEFSRLNEKTTIIFDPSPRI  180

Query  181  NKMNCESIRKLLEINTIVHANEGEILQLSSENHVKDAALEVSKQTNQPVIVTLGNKGTLI  240
            NKMNCESIRKLLEINTIVHANEGEILQLSSENHVKDAALEVSKQTNQPVIVTLGNKGTLI
Sbjct  181  NKMNCESIRKLLEINTIVHANEGEILQLSSENHVKDAALEVSKQTNQPVIVTLGNKGTLI  240

Query  241  ANKCKVKILEGEKVPVTDTIGAGDSHTAAFIAGLLDNQSIEKACIWGNEVASKIVQERGG  300
            ANKCKVKILEGEKVPVTDTIGAGDSHTAAFIAGLLDNQSIEKACIWGNEVASKIVQERGG
Sbjct  241  ANKCKVKILEGEKVPVTDTIGAGDSHTAAFIAGLLDNQSIEKACIWGNEVASKIVQERGG  300

Query  301  NTDIFNPIDKEY  312
            NTDIFNPIDKEY
Sbjct  301  NTDIFNPIDKEY  312

2) C248_0030 in NC_018608


> NC_002976_P3|4|G4|57865611|YP_189772.1|Staphylococcus_epidermidis_RP62A|-|1235..2173|-|SERP2216|ribokinase
Length=312

 Score =  457 bits (1721),  Expect = 4e-130, Method: Compositional matrix adjust.
 Identities = 288/294 (98%), Positives = 291/294 (99%), Gaps = 0/294 (0%)

Query  1    MIGSAVIDVILNVNSIPSSGSDEFAHSEKTIVGGCAYNVGDILSQFKANYDLMVPVGDGP  60
            +IGSAVIDVILNVNSIPSSGSDEFAHSEKTIVGGCAYNVGDILSQFKANYDLMVPVGDG 
Sbjct  19   VIGSAVIDVILNVNSIPSSGSDEFAHSEKTIVGGCAYNVGDILSQFKANYDLMVPVGDGL  78

Query  61   NGTIIENKLKKEGKTSLLNNILGDNGWTLCIVENNGERTFLTIPGVEMTWKKNWFKEIDL  120
            NGTIIENKLKKEGKTSLLNNILGDNGWTLCIVENNGERTFLTIPGVEMTWKKNWFKEIDL
Sbjct  79   NGTIIENKLKKEGKTSLLNNILGDNGWTLCIVENNGERTFLTIPGVEMTWKKNWFKEIDL  138

Query  121  NKYDYIYVSGYSFEPPSDEVLLEEFSRLNEKTTIIFDPSPRINKMNCESIRKLLEINTIV  180
            NKYDYIYVSGYSFEPPSDEVLLEEFSRLNEKTTIIFDPSPRINKMNCESIRKLLEINTIV
Sbjct  139  NKYDYIYVSGYSFEPPSDEVLLEEFSRLNEKTTIIFDPSPRINKMNCESIRKLLEINTIV  198

Query  181  HANEDEILQLSSENHVKDAALEVSKQTNQPVIVTLGNEGTLIANKCKVKILEGEKVPVTD  240
            HANE+EILQLSSENHVKDAALEVSKQTNQPVIVTLGN GTLIANKCKVKILEGEKVPVTD
Sbjct  199  HANEGEILQLSSENHVKDAALEVSKQTNQPVIVTLGNKGTLIANKCKVKILEGEKVPVTD  258

Query  241  TIGAGDSHTAAFIAGLLDNQSIEKACIWGNEVASKIVQEQGGNTDIFNPIDEEY  294
            TIGAGDSHTAAFIAGLLDNQSIEKACIWGNEVASKIVQE+GGNTDIFNPID EY
Sbjct  259  TIGAGDSHTAAFIAGLLDNQSIEKACIWGNEVASKIVQERGGNTDIFNPIDKEY  312

3) Lreu_0159 in NC_009513


> NC_002976_P3|4|G4|57865611|YP_189772.1|Staphylococcus_epidermidis_RP62A|-|1235..2173|-|SERP2216|ribokinase
Length=312

 Score =  192 bits (714),  Expect = 2e-50, Method: Compositional matrix adjust.
 Identities = 117/291 (41%), Positives = 196/291 (68%), Gaps = 4/291 (1%)

Query  3    KKSLIIGAAFVDVIMDVPQMPTSGSDVTAKLKSYNVGGCAFNVYGAIKHYLGANSADLFV  62
            KK L+IG+A +DVI++V  +P+SGSD  A      VGGCA+NV + + ++    + DL V
Sbjct  15   KKVLVIGSAVIDVILNVNSIPSSGSDEFAHSEKTIVGGCAYNVGDILSQF--KANYDLMV  72

Query  63   PVGKGQYSEIVRKTMNYSRIPILLEDNHQDNGWDLCLVEPNGERTFITVPGIEQDWKDEW  122
            PVG G  + I+ + ++      LL++   DNGW LC+VE NGERTF+T+PG+E  WK +W
Sbjct  73   PVGDGLNGTIIENKLKKEGKTSLLNNILGDNGWTLCIVENNGERTFLTIPGVEMTWKKNW  132

Query  123  FSKINLSDYKYFYVSGYEMEDVKSANLLLDYLEQRDNDSYILFDASPRISHIDSRILNRL  182
            F  I+L+ Y Y+YVSGY  E   S ++LL+ + + ++ + I+FD+SPRI+ ++   + +L
Sbjct  133  FKEIDLNKYDYIYVSGYSFEP-PSDEVLLEEFSRLNEKTTIIFDPSPRINKMNCESIRKL  191

Query  183  ITKGVIINANEDEIGFLSDRDTLEEKTSDVFEKTDEPVLVTLGAKGTYLYDDNGGRIISS  242
            +    I++ANE+EI  LS  + + + + +V  +T++PV+VTLG KGT + +    +I+ +
Sbjct  192  LEINTIVHANEGEILQLSSENHVKDAALEVSKQTNQPVIVTLGNKGTLIANKCKVKILEG  251

Query  243  DKVENVVNTIGAGDTHCGGVIAGLLNGNSFAEVCKIGNNLSAQVIQQEAGS  293
            +KV  V +TIGAGD+H ++ IAGLL+ +S+   C  GN+++++++Q+ +G+
Sbjct  252  EKV-PVTDTIGAGDSHTAAFIAGLLDNQSIEKACIWGNEVASKIVQERGGN  301

4) LAR_0152 in NC_010609


> NC_002976_P3|4|G4|57865611|YP_189772.1|Staphylococcus_epidermidis_RP62A|-|1235..2173|-|SERP2216|ribokinase
Length=312

 Score =  192 bits (714),  Expect = 2e-50, Method: Compositional matrix adjust.
 Identities = 117/291 (41%), Positives = 196/291 (68%), Gaps = 4/291 (1%)

Query  3    KKSLIIGAAFVDVIMDVPQMPTSGSDVTAKLKSYNVGGCAFNVYGAIKHYLGANSADLFV  62
            KK L+IG+A +DVI++V  +P+SGSD  A      VGGCA+NV + + ++    + DL V
Sbjct  15   KKVLVIGSAVIDVILNVNSIPSSGSDEFAHSEKTIVGGCAYNVGDILSQF--KANYDLMV  72

Query  63   PVGKGQYSEIVRKTMNYSRIPILLEDNHQDNGWDLCLVEPNGERTFITVPGIEQDWKDEW  122
            PVG G  + I+ + ++      LL++   DNGW LC+VE NGERTF+T+PG+E  WK +W
Sbjct  73   PVGDGLNGTIIENKLKKEGKTSLLNNILGDNGWTLCIVENNGERTFLTIPGVEMTWKKNW  132

Query  123  FSKINLSDYKYFYVSGYEMEDVKSANLLLDYLEQRDNDSYILFDASPRISHIDSRILNRL  182
            F  I+L+ Y Y+YVSGY  E   S ++LL+ + + ++ + I+FD+SPRI+ ++   + +L
Sbjct  133  FKEIDLNKYDYIYVSGYSFEP-PSDEVLLEEFSRLNEKTTIIFDPSPRINKMNCESIRKL  191

Query  183  ITKGVIINANEDEIGFLSDRDTLEEKTSDVFEKTDEPVLVTLGAKGTYLYDDNGGRIISS  242
            +    I++ANE+EI  LS  + + + + +V  +T++PV+VTLG KGT + +    +I+ +
Sbjct  192  LEINTIVHANEGEILQLSSENHVKDAALEVSKQTNQPVIVTLGNKGTLIANKCKVKILEG  251

Query  243  DKVENVVNTIGAGDTHCGGVIAGLLNGNSFAEVCKIGNNLSAQVIQQEAGS  293
            +KV  V +TIGAGD+H ++ IAGLL+ +S+   C  GN+++++++Q+ +G+
Sbjct  252  EKV-PVTDTIGAGDSHTAAFIAGLLDNQSIEKACIWGNEVASKIVQERGGN  301

5) LVIS_2233 in NC_008497


> NC_002976_P3|4|G4|57865611|YP_189772.1|Staphylococcus_epidermidis_RP62A|-|1235..2173|-|SERP2216|ribokinase
Length=312

 Score =  160 bits (591),  Expect = 8e-41, Method: Compositional matrix adjust.
 Identities = 103/254 (41%), Positives = 164/254 (65%), Gaps = 2/254 (0%)

Query  2    SKALVLGAAFVDVVVNVPRLPFSGGDVTGDLKSYRIGGSAFNVYGALRYMQASADLLVPV  61
             K LV+G+A +DV++NV  +P SG+D  ++     +GG A+NV + L   +A+ DL+VPV
Sbjct  15   KKVLVIGSAVIDVILNVNSIPSSGSDEFAHSEKTIVGGCAYNVGDILSQFKANYDLMVPV  74

Query  62   GEGDYATRVKQHLSNQGISLKLPVMGADNGWDLSLVEPNGERSFLTINGIEQCWKPQWFQ  121
            G+G  +T + + L ++G +  L  + +DNGW L +VE NGER+FLTI G+E  WK +WF+
Sbjct  75   GDGLNGTIIENKLKKEGKTSLLNNILGDNGWTLCIVENNGERTFLTIPGVEMTWKKNWFK  134

Query  122  QVQLADYDYIYVSGYELENLRSAKVILDGLRQRRPDAQILFDTSPRIGEIPSEILQYLLA  181
            +++L  YDYIYVSGY +E   S  V+L+ + +    + I+FD SPRI  +  E ++ LL 
Sbjct  135  EIDLNKYDYIYVSGYSFEP-PSDEVLLEEFSRLNEKTTIIFDPSPRINKMNCESIRKLLE  193

Query  182  ARVMVHCNEDEIGKIMPDGRTVAEKAHRLFALTQSPVMVTLGGQGTYYVDGTATGQVPAQ  241
               +VH NE+EI ++ ++ + V + A  +   T+ PV+VTLG +GT   +      + ++
Sbjct  194  INTIVHANEGEILQLSSENH-VKDAALEVSKQTNQPVIVTLGNKGTLIANKCKVKILEGE  252

Query  242  NVPVVNTIGAGDTH  255
            +VPV +TIGAGD+H
Sbjct  253  KVPVTDTIGAGDSH  266