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Homologs of tia gene of DQ095216

protein-level

Hit (GenBank Accn)

Product

Source Genome

Eval.

Ident.(%)

1) tia
( YP_854245.1 )

tia invasion determinant

NC_008563
(Escherichia coli APEC O1)

3e-112

100

2) tia
( YP_002410068.1 )

Tia invasion determinant

NC_011750
(Escherichia coli IAI39)

3e-112

100

3) tia
( YP_002410460.1 )

Tia invasion determinant

NC_011750
(Escherichia coli IAI39)

3e-112

100

4) tia
( YP_002392875.1 )

Tia invasion determinant

NC_011742
(Escherichia coli S88)

3e-112

100

5) tia
( YP_006146825.1 )

Tia invasion determinant

NC_017646
(Escherichia coli CE10)

2e-110

100

6) ETEC_3907
( YP_006117448.1 )

heat resistant agglutinin 1

NC_017633
(Escherichia coli ETEC H10407)

2e-105

7) ECNA114_4668
( YP_006141791.1 )

Putative peptide transport periplasmic protein

NC_017644
(Escherichia coli NA114)

9e-75

8) SN31241_6990
( YP_008358617.1 )

Heat resistant agglutinin 1

NC_021902
(Salmonella enterica USMARC-S3124.1)

9e-75

9) SeHA_C4728
( YP_002048359.1 )

heat resistant agglutinin 1

NC_011083
(Salmonella enterica SL476)

3e-73

10) EC55989_4831
( YP_002405688.1 )

surface protein precursor

NC_011748
(Escherichia coli 55989)

7e-70

11) EcSMS35_4755
( YP_001746676.1 )

heat resistant agglutinin 1

NC_010498
(Escherichia coli SMS-3-5)

7e-70

12) EC042_3176
( YP_006097468.1 )

heat resistant agglutinin 1

NC_017626
(Escherichia coli 042)

8e-70

13) UM146_21625
( YP_006113165.1 )

OmpA family protein

NC_017632
(Escherichia coli UM146)

9e-60

14) hek
( YP_543816.1 )

adhesin

NC_007946
(Escherichia coli UTI89)

9e-60

15) ECP_4525
( YP_672362.1 )

OmpA family protein

NC_008253
(Escherichia coli 536)

3e-59

16) ECABU_c48390
( YP_006108749.1 )

adhesin/virulence factor Hek

NC_017631
(Escherichia coli ABU 83972)

3e-59

• Sequence Alignments

1) tia in NC_008563


> DQ095216|4|G4|70608343|AAZ04415.1|Escherichia_coli_APEC_O1|-|7286..8041|tia|ORF_4|Tia 
invasion determinant
Length=251

 Score =  397 bits (1492),  Expect = 3e-112, Method: Compositional matrix adjust.
 Identities = 251/251 (100%), Positives = 251/251 (100%), Gaps = 0/251 (0%)

Query  1    MIEMKKVIVVSALAMAGVFSAQALADRGKTGFYVTGKAGASVVTQTDQRFRQDFGDDVYK  60
            MIEMKKVIVVSALAMAGVFSAQALADRGKTGFYVTGKAGASVVTQTDQRFRQDFGDDVYK
Sbjct  1    MIEMKKVIVVSALAMAGVFSAQALADRGKTGFYVTGKAGASVVTQTDQRFRQDFGDDVYK  60

Query  61   YKGGDKNDTVFGAGLAVGYDFYQHYNVPVRTEVEFYGRGAADSHYTLDTWHSPMGDGGRE  120
            YKGGDKNDTVFGAGLAVGYDFYQHYNVPVRTEVEFYGRGAADSHYTLDTWHSPMGDGGRE
Sbjct  61   YKGGDKNDTVFGAGLAVGYDFYQHYNVPVRTEVEFYGRGAADSHYTLDTWHSPMGDGGRE  120

Query  121  DTQNRLSVNTLMVNTYYDFRNSSAFTPWVSVGLGYARIHHKATYTDTSWNKSGEVSDISA  180
            DTQNRLSVNTLMVNTYYDFRNSSAFTPWVSVGLGYARIHHKATYTDTSWNKSGEVSDISA
Sbjct  121  DTQNRLSVNTLMVNTYYDFRNSSAFTPWVSVGLGYARIHHKATYTDTSWNKSGEVSDISA  180

Query  181  LHYSGYDNNFAWSIGAGVRYDITPDIALDLSYRYLDAGKSSLSYKDAEGDKYKSEADVKS  240
            LHYSGYDNNFAWSIGAGVRYDITPDIALDLSYRYLDAGKSSLSYKDAEGDKYKSEADVKS
Sbjct  181  LHYSGYDNNFAWSIGAGVRYDITPDIALDLSYRYLDAGKSSLSYKDAEGDKYKSEADVKS  240

Query  241  HDIMFGVTYNF  251
            HDIMFGVTYNF
Sbjct  241  HDIMFGVTYNF  251

2) tia in NC_011750


> DQ095216|4|G4|70608343|AAZ04415.1|Escherichia_coli_APEC_O1|-|7286..8041|tia|ORF_4|Tia 
invasion determinant
Length=251

 Score =  397 bits (1492),  Expect = 3e-112, Method: Compositional matrix adjust.
 Identities = 251/251 (100%), Positives = 251/251 (100%), Gaps = 0/251 (0%)

Query  1    MIEMKKVIVVSALAMAGVFSAQALADRGKTGFYVTGKAGASVVTQTDQRFRQDFGDDVYK  60
            MIEMKKVIVVSALAMAGVFSAQALADRGKTGFYVTGKAGASVVTQTDQRFRQDFGDDVYK
Sbjct  1    MIEMKKVIVVSALAMAGVFSAQALADRGKTGFYVTGKAGASVVTQTDQRFRQDFGDDVYK  60

Query  61   YKGGDKNDTVFGAGLAVGYDFYQHYNVPVRTEVEFYGRGAADSHYTLDTWHSPMGDGGRE  120
            YKGGDKNDTVFGAGLAVGYDFYQHYNVPVRTEVEFYGRGAADSHYTLDTWHSPMGDGGRE
Sbjct  61   YKGGDKNDTVFGAGLAVGYDFYQHYNVPVRTEVEFYGRGAADSHYTLDTWHSPMGDGGRE  120

Query  121  DTQNRLSVNTLMVNTYYDFRNSSAFTPWVSVGLGYARIHHKATYTDTSWNKSGEVSDISA  180
            DTQNRLSVNTLMVNTYYDFRNSSAFTPWVSVGLGYARIHHKATYTDTSWNKSGEVSDISA
Sbjct  121  DTQNRLSVNTLMVNTYYDFRNSSAFTPWVSVGLGYARIHHKATYTDTSWNKSGEVSDISA  180

Query  181  LHYSGYDNNFAWSIGAGVRYDITPDIALDLSYRYLDAGKSSLSYKDAEGDKYKSEADVKS  240
            LHYSGYDNNFAWSIGAGVRYDITPDIALDLSYRYLDAGKSSLSYKDAEGDKYKSEADVKS
Sbjct  181  LHYSGYDNNFAWSIGAGVRYDITPDIALDLSYRYLDAGKSSLSYKDAEGDKYKSEADVKS  240

Query  241  HDIMFGVTYNF  251
            HDIMFGVTYNF
Sbjct  241  HDIMFGVTYNF  251

3) tia in NC_011750


> DQ095216|4|G4|70608343|AAZ04415.1|Escherichia_coli_APEC_O1|-|7286..8041|tia|ORF_4|Tia 
invasion determinant
Length=251

 Score =  397 bits (1492),  Expect = 3e-112, Method: Compositional matrix adjust.
 Identities = 251/251 (100%), Positives = 251/251 (100%), Gaps = 0/251 (0%)

Query  1    MIEMKKVIVVSALAMAGVFSAQALADRGKTGFYVTGKAGASVVTQTDQRFRQDFGDDVYK  60
            MIEMKKVIVVSALAMAGVFSAQALADRGKTGFYVTGKAGASVVTQTDQRFRQDFGDDVYK
Sbjct  1    MIEMKKVIVVSALAMAGVFSAQALADRGKTGFYVTGKAGASVVTQTDQRFRQDFGDDVYK  60

Query  61   YKGGDKNDTVFGAGLAVGYDFYQHYNVPVRTEVEFYGRGAADSHYTLDTWHSPMGDGGRE  120
            YKGGDKNDTVFGAGLAVGYDFYQHYNVPVRTEVEFYGRGAADSHYTLDTWHSPMGDGGRE
Sbjct  61   YKGGDKNDTVFGAGLAVGYDFYQHYNVPVRTEVEFYGRGAADSHYTLDTWHSPMGDGGRE  120

Query  121  DTQNRLSVNTLMVNTYYDFRNSSAFTPWVSVGLGYARIHHKATYTDTSWNKSGEVSDISA  180
            DTQNRLSVNTLMVNTYYDFRNSSAFTPWVSVGLGYARIHHKATYTDTSWNKSGEVSDISA
Sbjct  121  DTQNRLSVNTLMVNTYYDFRNSSAFTPWVSVGLGYARIHHKATYTDTSWNKSGEVSDISA  180

Query  181  LHYSGYDNNFAWSIGAGVRYDITPDIALDLSYRYLDAGKSSLSYKDAEGDKYKSEADVKS  240
            LHYSGYDNNFAWSIGAGVRYDITPDIALDLSYRYLDAGKSSLSYKDAEGDKYKSEADVKS
Sbjct  181  LHYSGYDNNFAWSIGAGVRYDITPDIALDLSYRYLDAGKSSLSYKDAEGDKYKSEADVKS  240

Query  241  HDIMFGVTYNF  251
            HDIMFGVTYNF
Sbjct  241  HDIMFGVTYNF  251

4) tia in NC_011742


> DQ095216|4|G4|70608343|AAZ04415.1|Escherichia_coli_APEC_O1|-|7286..8041|tia|ORF_4|Tia 
invasion determinant
Length=251

 Score =  397 bits (1492),  Expect = 3e-112, Method: Compositional matrix adjust.
 Identities = 251/251 (100%), Positives = 251/251 (100%), Gaps = 0/251 (0%)

Query  1    MIEMKKVIVVSALAMAGVFSAQALADRGKTGFYVTGKAGASVVTQTDQRFRQDFGDDVYK  60
            MIEMKKVIVVSALAMAGVFSAQALADRGKTGFYVTGKAGASVVTQTDQRFRQDFGDDVYK
Sbjct  1    MIEMKKVIVVSALAMAGVFSAQALADRGKTGFYVTGKAGASVVTQTDQRFRQDFGDDVYK  60

Query  61   YKGGDKNDTVFGAGLAVGYDFYQHYNVPVRTEVEFYGRGAADSHYTLDTWHSPMGDGGRE  120
            YKGGDKNDTVFGAGLAVGYDFYQHYNVPVRTEVEFYGRGAADSHYTLDTWHSPMGDGGRE
Sbjct  61   YKGGDKNDTVFGAGLAVGYDFYQHYNVPVRTEVEFYGRGAADSHYTLDTWHSPMGDGGRE  120

Query  121  DTQNRLSVNTLMVNTYYDFRNSSAFTPWVSVGLGYARIHHKATYTDTSWNKSGEVSDISA  180
            DTQNRLSVNTLMVNTYYDFRNSSAFTPWVSVGLGYARIHHKATYTDTSWNKSGEVSDISA
Sbjct  121  DTQNRLSVNTLMVNTYYDFRNSSAFTPWVSVGLGYARIHHKATYTDTSWNKSGEVSDISA  180

Query  181  LHYSGYDNNFAWSIGAGVRYDITPDIALDLSYRYLDAGKSSLSYKDAEGDKYKSEADVKS  240
            LHYSGYDNNFAWSIGAGVRYDITPDIALDLSYRYLDAGKSSLSYKDAEGDKYKSEADVKS
Sbjct  181  LHYSGYDNNFAWSIGAGVRYDITPDIALDLSYRYLDAGKSSLSYKDAEGDKYKSEADVKS  240

Query  241  HDIMFGVTYNF  251
            HDIMFGVTYNF
Sbjct  241  HDIMFGVTYNF  251

5) tia in NC_017646


> DQ095216|4|G4|70608343|AAZ04415.1|Escherichia_coli_APEC_O1|-|7286..8041|tia|ORF_4|Tia 
invasion determinant
Length=251

 Score =  391 bits (1470),  Expect = 2e-110, Method: Compositional matrix adjust.
 Identities = 248/248 (100%), Positives = 248/248 (100%), Gaps = 0/248 (0%)

Query  1    MKKVIVVSALAMAGVFSAQALADRGKTGFYVTGKAGASVVTQTDQRFRQDFGDDVYKYKG  60
            MKKVIVVSALAMAGVFSAQALADRGKTGFYVTGKAGASVVTQTDQRFRQDFGDDVYKYKG
Sbjct  4    MKKVIVVSALAMAGVFSAQALADRGKTGFYVTGKAGASVVTQTDQRFRQDFGDDVYKYKG  63

Query  61   GDKNDTVFGAGLAVGYDFYQHYNVPVRTEVEFYGRGAADSHYTLDTWHSPMGDGGREDTQ  120
            GDKNDTVFGAGLAVGYDFYQHYNVPVRTEVEFYGRGAADSHYTLDTWHSPMGDGGREDTQ
Sbjct  64   GDKNDTVFGAGLAVGYDFYQHYNVPVRTEVEFYGRGAADSHYTLDTWHSPMGDGGREDTQ  123

Query  121  NRLSVNTLMVNTYYDFRNSSAFTPWVSVGLGYARIHHKATYTDTSWNKSGEVSDISALHY  180
            NRLSVNTLMVNTYYDFRNSSAFTPWVSVGLGYARIHHKATYTDTSWNKSGEVSDISALHY
Sbjct  124  NRLSVNTLMVNTYYDFRNSSAFTPWVSVGLGYARIHHKATYTDTSWNKSGEVSDISALHY  183

Query  181  SGYDNNFAWSIGAGVRYDITPDIALDLSYRYLDAGKSSLSYKDAEGDKYKSEADVKSHDI  240
            SGYDNNFAWSIGAGVRYDITPDIALDLSYRYLDAGKSSLSYKDAEGDKYKSEADVKSHDI
Sbjct  184  SGYDNNFAWSIGAGVRYDITPDIALDLSYRYLDAGKSSLSYKDAEGDKYKSEADVKSHDI  243

Query  241  MFGVTYNF  248
            MFGVTYNF
Sbjct  244  MFGVTYNF  251

6) ETEC_3907 in NC_017633


> DQ095216|4|G4|70608343|AAZ04415.1|Escherichia_coli_APEC_O1|-|7286..8041|tia|ORF_4|Tia 
invasion determinant
Length=251

 Score =  374 bits (1406),  Expect = 2e-105, Method: Compositional matrix adjust.
 Identities = 233/248 (94%), Positives = 243/248 (98%), Gaps = 0/248 (0%)

Query  1    MKKVIAVSALAMAGMFSAQALADESKTGFYVTGKAGASVVMQTDQRFRQDFGDDVYKYKG  60
            MKKVI VSALAMAG+FSAQALAD +KTGFYVTGKAGASVV QTDQRFRQDFGDDVYKYKG
Sbjct  4    MKKVIVVSALAMAGVFSAQALADRGKTGFYVTGKAGASVVTQTDQRFRQDFGDDVYKYKG  63

Query  61   GDKNDTVFGAGLAVGYDFYQHYNVPVRTEVEFYGRGAADSRYTLDTWRSPMGDGGREDTQ  120
            GDKNDTVFGAGLAVGYDFYQHYNVPVRTEVEFYGRGAADS+YTLDTW+SPMGDGGREDTQ
Sbjct  64   GDKNDTVFGAGLAVGYDFYQHYNVPVRTEVEFYGRGAADSHYTLDTWHSPMGDGGREDTQ  123

Query  121  NRLSVNTLMVNTYYDFRNSSAFTPWVSVGLGYARVHHKATYIDTSWNESGEISDISALHY  180
            NRLSVNTLMVNTYYDFRNSSAFTPWVSVGLGYAR+HHKATY DTSWN SGE+SDISALHY
Sbjct  124  NRLSVNTLMVNTYYDFRNSSAFTPWVSVGLGYARIHHKATYTDTSWNKSGEVSDISALHY  183

Query  181  SGYDNNFAWSIGAGVRYDVTPDIALDLSYRYLDAGKSSLSYKDTEGDKYKSEADVKSHDI  240
            SGYDNNFAWSIGAGVRYD+TPDIALDLSYRYLDAGKSSLSYKD+EGDKYKSEADVKSHDI
Sbjct  184  SGYDNNFAWSIGAGVRYDITPDIALDLSYRYLDAGKSSLSYKDAEGDKYKSEADVKSHDI  243

Query  241  MLGVTYHF  248
            M+GVTY+F
Sbjct  244  MFGVTYNF  251

7) ECNA114_4668 in NC_017644


> DQ095216|4|G4|70608343|AAZ04415.1|Escherichia_coli_APEC_O1|-|7286..8041|tia|ORF_4|Tia 
invasion determinant
Length=251

 Score =  272 bits (1018),  Expect = 9e-75, Method: Compositional matrix adjust.
 Identities = 167/251 (67%), Positives = 212/251 (85%), Gaps = 3/251 (1%)

Query  1    MIEMKKVIAVSTLAMAGMFSAQTLADENKTGFYVTGKAGVSVMSLSEQRFVDGEGAWADK  60
            MIEMKKVI VS+LAMAG+FSAQ+LAD  KTGFYVTGKAG SV++ ++QRF ++ G    K
Sbjct  1    MIEMKKVIVVSALAMAGVFSAQALADRGKTGFYVTGKAGASVVTQTDQRFRQDFGDDVYK  60

Query  61   YKGSDKSDTVFGAGLAVGYDFYQHYNVPVRTEVEFYGRGNAESKYRLSYWESA-GGAEFD  119
            YKG+DK+DTVFGAGLAVGYDFYQHYNVPVRTEVEFYGRG A+S Y L  W+S+ G++  +
Sbjct  61   YKGGDKNDTVFGAGLAVGYDFYQHYNVPVRTEVEFYGRGAADSHYTLDTWHSPMGDGGRE  120

Query  120  DAQNKLSVNTLMLNAYYDFRNSSAFTPWISAGLGYARVHHKTSYIYT--DNSPAGSEVYS  177
            D+QN+LSVNTLM+N+YYDFRNSSAFTPW+S GLGYAR+HHK++Y  T  ++S   S++ +
Sbjct  121  DTQNRLSVNTLMVNTYYDFRNSSAFTPWVSVGLGYARIHHKATYTDTSWNKSGEVSDISA  180

Query  178  ASASKYENNLAWSLGAGVKYDVTQDFSLDLSYRYLDAGDSTLTYKDEDGAKYKSSVDVRS  237
               S Y+NN+AWS+GAGV+YD+T D++LDLSYRYLDAG S+L+YKD +G KYKS  DV+S
Sbjct  181  LHYSGYDNNFAWSIGAGVRYDITPDIALDLSYRYLDAGKSSLSYKDAEGDKYKSEADVKS  240

Query  238  NEFMLGATYNF  248
            +++M+G TYNF
Sbjct  241  HDIMFGVTYNF  251

8) SN31241_6990 in NC_021902


> DQ095216|4|G4|70608343|AAZ04415.1|Escherichia_coli_APEC_O1|-|7286..8041|tia|ORF_4|Tia 
invasion determinant
Length=251

 Score =  272 bits (1018),  Expect = 9e-75, Method: Compositional matrix adjust.
 Identities = 167/251 (67%), Positives = 212/251 (85%), Gaps = 3/251 (1%)

Query  1    MIEMKKVIAVSTLAMAGMFSAQTLADENKTGFYVTGKAGVSVMSLSEQRFVDGEGAWADK  60
            MIEMKKVI VS+LAMAG+FSAQ+LAD  KTGFYVTGKAG SV++ ++QRF ++ G    K
Sbjct  1    MIEMKKVIVVSALAMAGVFSAQALADRGKTGFYVTGKAGASVVTQTDQRFRQDFGDDVYK  60

Query  61   YKGSDKSDTVFGAGLAVGYDFYQHYNVPVRTEVEFYGRGNAESKYRLSYWESA-GGAEFD  119
            YKG+DK+DTVFGAGLAVGYDFYQHYNVPVRTEVEFYGRG A+S Y L  W+S+ G++  +
Sbjct  61   YKGGDKNDTVFGAGLAVGYDFYQHYNVPVRTEVEFYGRGAADSHYTLDTWHSPMGDGGRE  120

Query  120  DAQNKLSVNTLMLNAYYDFRNSSAFTPWISAGLGYARVHHKTSYIYT--DNSPAGSEVYS  177
            D+QN+LSVNTLM+N+YYDFRNSSAFTPW+S GLGYAR+HHK++Y  T  ++S   S++ +
Sbjct  121  DTQNRLSVNTLMVNTYYDFRNSSAFTPWVSVGLGYARIHHKATYTDTSWNKSGEVSDISA  180

Query  178  ASASKYENNLAWSLGAGVKYDVTQDFSLDLSYRYLDAGDSTLTYKDEDGAKYKSSVDVRS  237
               S Y+NN+AWS+GAGV+YD+T D++LDLSYRYLDAG S+L+YKD +G KYKS  DV+S
Sbjct  181  LHYSGYDNNFAWSIGAGVRYDITPDIALDLSYRYLDAGKSSLSYKDAEGDKYKSEADVKS  240

Query  238  NEFMLGATYNF  248
            +++M+G TYNF
Sbjct  241  HDIMFGVTYNF  251

9) SeHA_C4728 in NC_011083


> DQ095216|4|G4|70608343|AAZ04415.1|Escherichia_coli_APEC_O1|-|7286..8041|tia|ORF_4|Tia 
invasion determinant
Length=251

 Score =  267 bits (998),  Expect = 3e-73, Method: Compositional matrix adjust.
 Identities = 164/248 (67%), Positives = 209/248 (85%), Gaps = 3/248 (1%)

Query  1    MKKVIAVSTLAMAGMFSAQTLADENKTGFYVTGKAGVSVMSLSEQRFVDGEGAWADKYKG  60
            MKKVI VS+LAMAG+FSAQ+LAD  KTGFYVTGKAG SV++ ++QRF ++ G    KYKG
Sbjct  4    MKKVIVVSALAMAGVFSAQALADRGKTGFYVTGKAGASVVTQTDQRFRQDFGDDVYKYKG  63

Query  61   SDKSDTVFGAGLAVGYDFYQHYNVPVRTEVEFYGRGNAESKYRLSYWESA-GGAEFDDAQ  119
            +DK+DTVFGAGLAVGYDFYQHYNVPVRTEVEFYGRG A+S Y L  W+S+ G++  +D+Q
Sbjct  64   GDKNDTVFGAGLAVGYDFYQHYNVPVRTEVEFYGRGAADSHYTLDTWHSPMGDGGREDTQ  123

Query  120  NKLSVNTLMLNAYYDFRNSSAFTPWISAGLGYARVHHKTSYIYT--DNSPAGSEVYSASA  177
            N+LSVNTLM+N+YYDFRNSSAFTPW+S GLGYAR+HHK++Y  T  ++S   S++ +   
Sbjct  124  NRLSVNTLMVNTYYDFRNSSAFTPWVSVGLGYARIHHKATYTDTSWNKSGEVSDISALHY  183

Query  178  SKYENNLAWSLGAGVKYDVTQDFSLDLSYRYLDAGDSTLTYKDEDGAKYKSSVDVRSNEF  237
            S Y+NN+AWS+GAGV+YD+T D++LDLSYRYLDAG S+L+YKD +G KYKS  DV+S+++
Sbjct  184  SGYDNNFAWSIGAGVRYDITPDIALDLSYRYLDAGKSSLSYKDAEGDKYKSEADVKSHDI  243

Query  238  MLGATYNF  245
            M+G TYNF
Sbjct  244  MFGVTYNF  251

10) EC55989_4831 in NC_011748


> DQ095216|4|G4|70608343|AAZ04415.1|Escherichia_coli_APEC_O1|-|7286..8041|tia|ORF_4|Tia 
invasion determinant
Length=251

 Score =  256 bits (956),  Expect = 7e-70, Method: Compositional matrix adjust.
 Identities = 168/255 (66%), Positives = 210/255 (83%), Gaps = 10/255 (3%)

Query  15   MIEMNKVIAVSALAMAGMFSTQALADESKTGFYVTGKAGASVMSLADQRFLSGDGEETSK  74
            MIEM+KVI VSALAMAG+FS+QALAD +KTGFYVTGKAGASV++ +DQRF  + G++  K
Sbjct  1    MIEMKKVIVVSALAMAGVFSAQALADRGKTGFYVTGKAGASVVTQTDQRFRQDFGDDVYK  60

Query  75   YKGGDGHDTVFSGGIAAGYDFYPQFSIPVRTELEFYARGKADSKYNVDKDSW-----SGG  129
            YKGGD +DTVF++G+A GYDFY ++++PVRTE+EFY+RG ADS Y +  D+W      GG
Sbjct  61   YKGGDKNDTVFGAGLAVGYDFYQHYNVPVRTEVEFYGRGAADSHYTL--DTWHSPMGDGG  118

Query  130  YWRDDLKNEVSVNTLMLNAYYDFRNDSAFTPWVSAGIGYARIHQKTT-GISTWDygygss  188
              R+D +N +SVNTLM+N+YYDFRN SAFTPWVS G+GYARIH+K+T   ++W+ +   S
Sbjct  119  --REDTQNRLSVNTLMVNTYYDFRNSSAFTPWVSVGLGYARIHHKATYTDTSWNKSGEVS  176

Query  189  greslsrsgsADNFAWSLGAGVRYDVTPDIALDLSYRYLDAGDSSVSYKDEWGDKYKSEV  248
            +  +L  SG  +NFAWS+GAGVRYD+TPDIALDLSYRYLDAG SS+SYKD  GDKYKSE 
Sbjct  177  DISALHYSGYDNNFAWSIGAGVRYDITPDIALDLSYRYLDAGKSSLSYKDAEGDKYKSEA  236

Query  249  DVKSHDILLGVTYNF  263
            DVKSHDI++GVTYNF
Sbjct  237  DVKSHDIMFGVTYNF  251

11) EcSMS35_4755 in NC_010498


> DQ095216|4|G4|70608343|AAZ04415.1|Escherichia_coli_APEC_O1|-|7286..8041|tia|ORF_4|Tia 
invasion determinant
Length=251

 Score =  256 bits (956),  Expect = 7e-70, Method: Compositional matrix adjust.
 Identities = 168/255 (66%), Positives = 210/255 (83%), Gaps = 10/255 (3%)

Query  15   MIEMNKVIAVSALAMAGMFSTQALADESKTGFYVTGKAGASVMSLADQRFLSGDGEETSK  74
            MIEM+KVI VSALAMAG+FS+QALAD +KTGFYVTGKAGASV++ +DQRF  + G++  K
Sbjct  1    MIEMKKVIVVSALAMAGVFSAQALADRGKTGFYVTGKAGASVVTQTDQRFRQDFGDDVYK  60

Query  75   YKGGDGHDTVFSGGIAAGYDFYPQFSIPVRTELEFYARGKADSKYNVDKDSW-----SGG  129
            YKGGD +DTVF++G+A GYDFY ++++PVRTE+EFY+RG ADS Y +  D+W      GG
Sbjct  61   YKGGDKNDTVFGAGLAVGYDFYQHYNVPVRTEVEFYGRGAADSHYTL--DTWHSPMGDGG  118

Query  130  YWRDDLKNEVSVNTLMLNAYYDFRNDSAFTPWVSAGIGYARIHQKTT-GISTWDygygss  188
              R+D +N +SVNTLM+N+YYDFRN SAFTPWVS G+GYARIH+K+T   ++W+ +   S
Sbjct  119  --REDTQNRLSVNTLMVNTYYDFRNSSAFTPWVSVGLGYARIHHKATYTDTSWNKSGEVS  176

Query  189  greslsrsgsADNFAWSLGAGVRYDVTPDIALDLSYRYLDAGDSSVSYKDEWGDKYKSEV  248
            +  +L  SG  +NFAWS+GAGVRYD+TPDIALDLSYRYLDAG SS+SYKD  GDKYKSE 
Sbjct  177  DISALHYSGYDNNFAWSIGAGVRYDITPDIALDLSYRYLDAGKSSLSYKDAEGDKYKSEA  236

Query  249  DVKSHDILLGVTYNF  263
            DVKSHDI++GVTYNF
Sbjct  237  DVKSHDIMFGVTYNF  251

12) EC042_3176 in NC_017626


> DQ095216|4|G4|70608343|AAZ04415.1|Escherichia_coli_APEC_O1|-|7286..8041|tia|ORF_4|Tia 
invasion determinant
Length=251

 Score =  256 bits (956),  Expect = 8e-70, Method: Compositional matrix adjust.
 Identities = 169/255 (67%), Positives = 210/255 (83%), Gaps = 10/255 (3%)

Query  15   MIEMNKVIAVSALAMAGMFSTQALADESKTGFYVTGKAGASVMSLADQRFLSGDGEETSK  74
            MIEM+KVI VSALAMAG+FS+QALAD +KTGFYVTGKAGASV++ +DQRF  + G++  K
Sbjct  1    MIEMKKVIVVSALAMAGVFSAQALADRGKTGFYVTGKAGASVVTQTDQRFRQDFGDDVYK  60

Query  75   YKGGDGHDTVFSGGIAAGYDFYPQFSIPVRTELEFYARGKADSKYNVDKDSW-----SGG  129
            YKGGD +DTVF++G+A GYDFY ++++PVRTE+EFY+RG ADS Y +  D+W      GG
Sbjct  61   YKGGDKNDTVFGAGLAVGYDFYQHYNVPVRTEVEFYGRGAADSHYTL--DTWHSPMGDGG  118

Query  130  YWRDDLKNEVSVNTLMLNAYYDFRNDSAFTPWVSAGIGYARIHQKTT-GISTWDygygss  188
              R+D +N +SVNTLM+N+YYDFRN SAFTPWVS G+GYARIH+K+T   ++W+ +   S
Sbjct  119  --REDTQNRLSVNTLMVNTYYDFRNSSAFTPWVSVGLGYARIHHKATYTDTSWNKSGEVS  176

Query  189  greslsrsgsADNFAWSFGAGVRYDVTPDIALDLSYRYLDAGDSSVSYKDEWGDKYKSEV  248
            +  +L  SG  +NFAWS+GAGVRYD+TPDIALDLSYRYLDAG SS+SYKD  GDKYKSE 
Sbjct  177  DISALHYSGYDNNFAWSIGAGVRYDITPDIALDLSYRYLDAGKSSLSYKDAEGDKYKSEA  236

Query  249  DVKSHDIMLGVTYNF  263
            DVKSHDIM+GVTYNF
Sbjct  237  DVKSHDIMFGVTYNF  251

13) UM146_21625 in NC_017632


> DQ095216|4|G4|70608343|AAZ04415.1|Escherichia_coli_APEC_O1|-|7286..8041|tia|ORF_4|Tia 
invasion determinant
Length=251

 Score =  222 bits (828),  Expect = 9e-60, Method: Compositional matrix adjust.
 Identities = 159/255 (63%), Positives = 204/255 (80%), Gaps = 10/255 (3%)

Query  3    IIEMNKvfvvsvvaaacvfavnagaKEGKSGFYLTGKAGASVMSLSDQRFLSGDEEETSK  62
            +IEM+KV+VVS +A A VF+ +A A  GK+GFY+TGKAGASV++ +DQRF  +  ++  K
Sbjct  1    MIEMKKVIVVSALAMAGVFSAQALADRGKTGFYVTGKAGASVVTQTDQRFRQDFGDDVYK  60

Query  63   YKGGDDHDTVFSGGIAVGYDFYPQFSIPVRTELEFYARGKADSKYNVDKDSW-----SGG  117
            YKGGD +DTVF++G+AVGYDFY ++++PVRTE+EFY+RG ADS Y +  D+W      GG
Sbjct  61   YKGGDKNDTVFGAGLAVGYDFYQHYNVPVRTEVEFYGRGAADSHYTL--DTWHSPMGDGG  118

Query  118  YWRDDLKNEVSVNTLMLNAYYDFRNDSAFTPWVSAGIGYARIHQKTT-GISTWDyeygss  176
              R+D +N +SVNTLM+N+YYDFRN SAFTPWVS G+GYARIH+K+T   ++W+     S
Sbjct  119  --REDTQNRLSVNTLMVNTYYDFRNSSAFTPWVSVGLGYARIHHKATYTDTSWNKSGEVS  176

Query  177  greslsrsgsADNFAWSLGAGVRYDVTPDIALDLSYRYLDAGDSSVSYKDEWGDKYKSEV  236
            +  +L  SG  +NFAWS+GAGVRYD+TPDIALDLSYRYLDAG SS+SYKD  GDKYKSE 
Sbjct  177  DISALHYSGYDNNFAWSIGAGVRYDITPDIALDLSYRYLDAGKSSLSYKDAEGDKYKSEA  236

Query  237  DVKSHDIMLGMTYNF  251
            DVKSHDIM+G+TYNF
Sbjct  237  DVKSHDIMFGVTYNF  251

14) hek in NC_007946


> DQ095216|4|G4|70608343|AAZ04415.1|Escherichia_coli_APEC_O1|-|7286..8041|tia|ORF_4|Tia 
invasion determinant
Length=251

 Score =  222 bits (828),  Expect = 9e-60, Method: Compositional matrix adjust.
 Identities = 159/255 (63%), Positives = 204/255 (80%), Gaps = 10/255 (3%)

Query  3    IIEMNKvfvvsvvaaacvfavnagaKEGKSGFYLTGKAGASVMSLSDQRFLSGDEEETSK  62
            +IEM+KV+VVS +A A VF+ +A A  GK+GFY+TGKAGASV++ +DQRF  +  ++  K
Sbjct  1    MIEMKKVIVVSALAMAGVFSAQALADRGKTGFYVTGKAGASVVTQTDQRFRQDFGDDVYK  60

Query  63   YKGGDDHDTVFSGGIAVGYDFYPQFSIPVRTELEFYARGKADSKYNVDKDSW-----SGG  117
            YKGGD +DTVF++G+AVGYDFY ++++PVRTE+EFY+RG ADS Y +  D+W      GG
Sbjct  61   YKGGDKNDTVFGAGLAVGYDFYQHYNVPVRTEVEFYGRGAADSHYTL--DTWHSPMGDGG  118

Query  118  YWRDDLKNEVSVNTLMLNAYYDFRNDSAFTPWVSAGIGYARIHQKTT-GISTWDyeygss  176
              R+D +N +SVNTLM+N+YYDFRN SAFTPWVS G+GYARIH+K+T   ++W+     S
Sbjct  119  --REDTQNRLSVNTLMVNTYYDFRNSSAFTPWVSVGLGYARIHHKATYTDTSWNKSGEVS  176

Query  177  greslsrsgsADNFAWSLGAGVRYDVTPDIALDLSYRYLDAGDSSVSYKDEWGDKYKSEV  236
            +  +L  SG  +NFAWS+GAGVRYD+TPDIALDLSYRYLDAG SS+SYKD  GDKYKSE 
Sbjct  177  DISALHYSGYDNNFAWSIGAGVRYDITPDIALDLSYRYLDAGKSSLSYKDAEGDKYKSEA  236

Query  237  DVKSHDIMLGMTYNF  251
            DVKSHDIM+G+TYNF
Sbjct  237  DVKSHDIMFGVTYNF  251

15) ECP_4525 in NC_008253


> DQ095216|4|G4|70608343|AAZ04415.1|Escherichia_coli_APEC_O1|-|7286..8041|tia|ORF_4|Tia 
invasion determinant
Length=251

 Score =  221 bits (822),  Expect = 3e-59, Method: Compositional matrix adjust.
 Identities = 145/228 (64%), Positives = 183/228 (81%), Gaps = 10/228 (4%)

Query  25   GKSGFYLTGKAGASVVSLSDQRFLSGDEEETSKYKGGDDHDTVFSGGIAAGYDFYPQFSI  84
            GK+GFY+TGKAGASVV+ +DQRF  +  ++  KYKGGD +DTVF++G+A GYDFY ++++
Sbjct  28   GKTGFYVTGKAGASVVTQTDQRFRQDFGDDVYKYKGGDKNDTVFGAGLAVGYDFYQHYNV  87

Query  85   PVRTELEFYARGKADSKYNVDKDSW-----SGGYWRDDLKNEVSVNTLMLNAYYDFRNDS  139
            PVRTE+EFY+RG ADS Y +D  +W      GG  R+D +N +SVNTLM+N+YYDFRN S
Sbjct  88   PVRTEVEFYGRGAADSHYTLD--TWHSPMGDGG--REDTQNRLSVNTLMVNTYYDFRNSS  143

Query  140  AFTPWVSAGIGYARIHQKTT-GISTWDyeygssgreslsrsgsADNFAWSLGAGVRYDVT  198
            AFTPWVS G+GYARIH+K+T   ++W+     S+  +L  SG  +NFAWS+GAGVRYD+T
Sbjct  144  AFTPWVSVGLGYARIHHKATYTDTSWNKSGEVSDISALHYSGYDNNFAWSIGAGVRYDIT  203

Query  199  PDIALDLSYRYLDAGDSSVSYKDEWGDKYKSEVDVKSHDIMLGMTYNF  246
            PDIALDLSYRYLDAG SS+SYKD  GDKYKSE DVKSHDIM+G+TYNF
Sbjct  204  PDIALDLSYRYLDAGKSSLSYKDAEGDKYKSEADVKSHDIMFGVTYNF  251

16) ECABU_c48390 in NC_017631


> DQ095216|4|G4|70608343|AAZ04415.1|Escherichia_coli_APEC_O1|-|7286..8041|tia|ORF_4|Tia 
invasion determinant
Length=251

 Score =  221 bits (822),  Expect = 3e-59, Method: Compositional matrix adjust.
 Identities = 145/228 (64%), Positives = 183/228 (81%), Gaps = 10/228 (4%)

Query  25   GKSGFYLTGKAGASVVSLSDQRFLSGDEEETSKYKGGDDHDTVFSGGIAAGYDFYPQFSI  84
            GK+GFY+TGKAGASVV+ +DQRF  +  ++  KYKGGD +DTVF++G+A GYDFY ++++
Sbjct  28   GKTGFYVTGKAGASVVTQTDQRFRQDFGDDVYKYKGGDKNDTVFGAGLAVGYDFYQHYNV  87

Query  85   PVRTELEFYARGKADSKYNVDKDSW-----SGGYWRDDLKNEVSVNTLMLNAYYDFRNDS  139
            PVRTE+EFY+RG ADS Y +D  +W      GG  R+D +N +SVNTLM+N+YYDFRN S
Sbjct  88   PVRTEVEFYGRGAADSHYTLD--TWHSPMGDGG--REDTQNRLSVNTLMVNTYYDFRNSS  143

Query  140  AFTPWVSAGIGYARIHQKTT-GISTWDyeygssgreslsrsgsADNFAWSLGAGVRYDVT  198
            AFTPWVS G+GYARIH+K+T   ++W+     S+  +L  SG  +NFAWS+GAGVRYD+T
Sbjct  144  AFTPWVSVGLGYARIHHKATYTDTSWNKSGEVSDISALHYSGYDNNFAWSIGAGVRYDIT  203

Query  199  PDIALDLSYRYLDAGDSSVSYKDEWGDKYKSEVDVKSHDIMLGMTYNF  246
            PDIALDLSYRYLDAG SS+SYKD  GDKYKSE DVKSHDIM+G+TYNF
Sbjct  204  PDIALDLSYRYLDAGKSSLSYKDAEGDKYKSEADVKSHDIMFGVTYNF  251