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Homologs of topB-2 gene of NC_004668_R1

protein-level

Hit (GenBank Accn)

Product

Source Genome

Eval.

Ident.(%)

1) topB-2
( NP_815968.1 )

DNA topoisomerase III

NC_004668
(Enterococcus faecalis V583)

0.0

100

2) CLS_04840
( YP_007848302.1 )

DNA topoisomerase III, bacteria and conjugative plasmid

NC_021047
(Clostridium saccharolyticum K10)

0.0

3) FP2_09300
( YP_007836783.1 )

DNA topoisomerase III, bacteria and conjugative plasmid

NC_021042
(Faecalibacterium prausnitzii L2/6)

0.0

4) topB
( YP_004882732.1 )

DNA topoisomerase III

NC_016048
(Oscillibacter valericigenes Sjm18-20)

0.0

5) CK5_29340
( YP_007806168.1 )

DNA topoisomerase III, bacteria and conjugative plasmid

NC_021022
([Ruminococcus] obeum A2-162)

0.0

6) Ethha_1903
( YP_004092156.1 )

DNA topoisomerase III

NC_014828
(Ethanoligenens harbinense YUAN-3)

0.0

7) EUR_07600
( YP_007772051.1 )

DNA topoisomerase III, bacteria and conjugative plasmid

NC_021010
(Eubacterium rectale DSM 17629)

0.0

8) EC1_10280
( YP_007798169.1 )

DNA topoisomerase III, bacteria and conjugative plasmid

NC_021019
(Eubacterium cylindroides T2-87)

0.0

9) RTO_00720
( YP_007785385.1 )

DNA topoisomerase III, bacteria and conjugative plasmid

NC_021015
([Ruminococcus] torques L2-14)

0.0

10) RHOM_01890
( YP_004837432.1 )

DNA topoisomerase III

NC_015977
(Roseburia hominis A2-183)

0.0

11) Closa_3709
( YP_003823852.1 )

DNA topoisomerase III

NC_014376
(Clostridium saccharolyticum WM1)

0.0

12) EUS_14250
( YP_007775462.1 )

DNA topoisomerase III, bacteria and conjugative plasmid

NC_021011
(Eubacterium siraeum 70/3)

0.0

13) FPR_14240
( YP_007800103.1 )

DNA topoisomerase III, bacteria and conjugative plasmid

NC_021020
(Faecalibacterium prausnitzii SL3/3)

0.0

14) topB
( YP_001087593.1 )

DNA topoisomerase III

NC_009089
(Clostridium difficile 630)

0.0

15) ES1_15040
( YP_007839991.1 )

DNA topoisomerase III, bacteria and conjugative plasmid

NC_021043
(Eubacterium siraeum V10Sc8a)

0.0

16) RBR_01000
( YP_007780333.1 )

DNA topoisomerase III, bacteria and conjugative plasmid

NC_021013
(Ruminococcus bromii L2-63)

0.0

17) CK5_22580
( YP_007805585.1 )

DNA topoisomerase III, bacteria and conjugative plasmid

NC_021022
([Ruminococcus] obeum A2-162)

0.0

18) CLS_29900
( YP_007850277.1 )

DNA topoisomerase III, bacteria and conjugative plasmid

NC_021047
(Clostridium saccharolyticum K10)

3e-180

19) EFAU004_02790
( YP_005355988.1 )

DNA topoisomerase III

NC_017022
(Enterococcus faecium Aus0004)

6e-174

20) EFAU085_00720
( YP_008394244.1 )

DNA topoisomerase III

NC_021994
(Enterococcus faecium AUS0085)

6e-174

21) EUBREC_3570
( YP_002939430.1 )

DNA topoisomerase

NC_012781
(Eubacterium rectale ATCC 33656)

8e-174

22) CCU_07970
( YP_007795898.1 )

DNA topoisomerase III, bacteria and conjugative plasmid

NC_021018
(Coprococcus sp. ART55/1)

5e-171

23) RHOM_15375
( YP_004840113.1 )

DNA topoisomerase III

NC_015977
(Roseburia hominis A2-183)

1e-167

24) CK5_35660
( YP_007806715.1 )

DNA topoisomerase III, bacteria and conjugative plasmid

NC_021022
([Ruminococcus] obeum A2-162)

3e-167

25) FP2_00540
( YP_007836050.1 )

DNA topoisomerase III, bacteria and conjugative plasmid

NC_021042
(Faecalibacterium prausnitzii L2/6)

8e-167

26) topB
( YP_006912025.1 )

DNA topoisomerase III

NC_018867
(Dehalobacter sp. CF)

8e-165

27) RBR_21180
( YP_007782015.1 )

Topoisomerase IA

NC_021013
(Ruminococcus bromii L2-63)

6e-158

28) CK5_04590
( YP_007804031.1 )

DNA topoisomerase III, bacteria and conjugative plasmid

NC_021022
([Ruminococcus] obeum A2-162)

6e-156

29) CC1_26110
( YP_007770654.1 )

DNA topoisomerase III, bacteria and conjugative plasmid

NC_021009
(Coprococcus catus GD/7)

4e-147

30) FPR_01100
( YP_007798966.1 )

Topoisomerase IA

NC_021020
(Faecalibacterium prausnitzii SL3/3)

9e-143

31) CD630_18590
( YP_001088366.1 )

DNA topoisomerase protein, type IA,Tn1549-like,CTn5-Orf16

NC_009089
(Clostridium difficile 630)

6e-129

32) SANR_1304
( YP_008501012.1 )

putative DNA topoisomerase

NC_022239
(Streptococcus anginosus C238)

6e-129

33) CDR20291_1793
( YP_003218283.1 )

DNA topoisomerase

NC_013316
(Clostridium difficile R20291)

2e-128

34) SZO_12820
( YP_002744799.1 )

DNA topoisomerase

NC_012470
(Streptococcus equi H70)

5e-128

35) CD630_04210
( YP_001086889.1 )

DNA topoisomerase protein, type IA,Tn1549-like,CTn2-Orf16

NC_009089
(Clostridium difficile 630)

7e-128

36) topA
( YP_006859871.1 )

DNA topoisomerase III

NC_018712
(Streptococcus dysgalactiae RE378)

2e-126

37) SANR_1853
( YP_008501522.1 )

putative DNA topoisomerase

NC_022239
(Streptococcus anginosus C238)

4e-126

38) SANR_1345
( YP_008501051.1 )

putative DNA topoisomerase

NC_022239
(Streptococcus anginosus C238)

5e-126

39) SEQ_1256
( YP_002746546.1 )

DNA topoisomerase

NC_012471
(Streptococcus equi 4047)

1e-125

40) SII_1009
( YP_008497180.1 )

putative DNA topoisomerase

NC_022237
(Streptococcus intermedius C270)

1e-125

41) SDSE_1343
( YP_006904895.1 )

DNA topoisomerase III

NC_019042
(Streptococcus dysgalactiae AC-2713)

3e-125

42) SDE12394_07175
( YP_006013463.1 )

DNA topoisomerase

NC_017567
(Streptococcus dysgalactiae ATCC 12394)

3e-125

43) SIR_0986
( YP_008512919.1 )

putative DNA topoisomerase

NC_022246
(Streptococcus intermedius B196)

1e-123

44) HMPREF0389_00190
( YP_005054189.1 )

DNA topoisomerase III

NC_016630
(Filifactor alocis ATCC 35896)

3e-123

45) SCI_1283
( YP_008499205.1 )

putative DNA topoisomerase

NC_022238
(Streptococcus constellatus C1050)

6e-123

46) SCRE_1224
( YP_008495615.1 )

putative DNA topoisomerase

NC_022236
(Streptococcus constellatus C232)

6e-123

47) SCR2_1224
( YP_008511377.1 )

putative DNA topoisomerase

NC_022245
(Streptococcus constellatus C818)

6e-123

48) SIR_1325
( YP_008513256.1 )

putative DNA topoisomerase

NC_022246
(Streptococcus intermedius B196)

2e-118

49) SAIL_7480
( YP_008117367.1 )

DNA topoisomerase III

NC_021507
(Streptococcus agalactiae ILRI112)

5e-118

50) Rxyl_0752
( YP_643532.1 )

DNA topoisomerase III

NC_008148
(Rubrobacter xylanophilus DSM 9941)

1e-117

51) SPAP_0887
( YP_003876478.1 )

topoisomerase IA

NC_014494
(Streptococcus pneumoniae AP200)

2e-115

52) HMPREF0389_00657
( YP_005054797.1 )

DNA topoisomerase III

NC_016630
(Filifactor alocis ATCC 35896)

9e-115

53) MGAS10750_Spy1696
( YP_603190.1 )

DNA topoisomerase III

NC_008024
(Streptococcus pyogenes MGAS10750)

4e-114

54) FMG_0956
( YP_001692264.1 )

DNA topoisomerase III

NC_010376
(Finegoldia magna ATCC 29328)

9e-114

55) Apre_1822
( YP_003142397.1 )

DNA topoisomerase type IA central domain-containing protein

NC_013164
(Anaerococcus prevotii DSM 20548)

1e-112

56) Dtox_2001
( YP_003191459.1 )

DNA topoisomerase III

NC_013216
(Desulfotomaculum acetoxidans DSM 771)

5e-109

57) Ccel_0922
( YP_002505269.1 )

DNA topoisomerase III

NC_011898
(Clostridium cellulolyticum H10)

1e-105

58) Clo1100_3206
( YP_005149158.1 )

DNA topoisomerase III

NC_016791
(Clostridium sp. BNL1100)

8e-105

59) B938_02020
( YP_007185110.1 )

DNA topoisomerase III

NC_019842
(Bacillus amyloliquefaciens AS43.3)

2e-104

60) topB
( YP_001420078.1 )

DNA topoisomerase III

NC_009725
(Bacillus amyloliquefaciens FZB42)

2e-104

61) SpiBuddy_1109
( YP_004247128.1 )

DNA topoisomerase III

NC_015152
(Sphaerochaeta globosa Buddy)

2e-104

62) Desku_2425
( YP_004517760.1 )

DNA topoisomerase III

NC_015573
(Desulfotomaculum kuznetsovii DSM 6115)

6e-104

63) FPR_19060
( YP_007800526.1 )

Topoisomerase IA

NC_021020
(Faecalibacterium prausnitzii SL3/3)

2e-101

• Sequence Alignments

1) topB-2 in NC_004668


> NC_004668_R1|30|G30|29376814|NP_815968.1|Enterococcus_faecalis_V583|-|30310..32427|topB-2|EF2312|DNA 
topoisomerase III
Length=705

 Score = 1080 bits (4096),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 705/705 (100%), Positives = 705/705 (100%), Gaps = 0/705 (0%)

Query  1    MQLVIAEKPSVGMALSKVLGAKSRGDGYMEGGGWLVSWCIGHLVELAPADAYDPRYSKWN  60
            MQLVIAEKPSVGMALSKVLGAKSRGDGYMEGGGWLVSWCIGHLVELAPADAYDPRYSKWN
Sbjct  1    MQLVIAEKPSVGMALSKVLGAKSRGDGYMEGGGWLVSWCIGHLVELAPADAYDPRYSKWN  60

Query  61   YADLPILPKPWQFQVLPDTKKQFEVLKTLIHRADVTALICATDAGREGELIFRLTYHLCG  120
            YADLPILPKPWQFQVLPDTKKQFEVLKTLIHRADVTALICATDAGREGELIFRLTYHLCG
Sbjct  61   YADLPILPKPWQFQVLPDTKKQFEVLKTLIHRADVTALICATDAGREGELIFRLTYHLCG  120

Query  121  CTKPVKRLWISSMEEAAIQKGFDNLLDGKNYDNLYAAALCRAKADWLIGINGTRLFTTLY  180
            CTKPVKRLWISSMEEAAIQKGFDNLLDGKNYDNLYAAALCRAKADWLIGINGTRLFTTLY
Sbjct  121  CTKPVKRLWISSMEEAAIQKGFDNLLDGKNYDNLYAAALCRAKADWLIGINGTRLFTTLY  180

Query  181  QGKSLNVGRVQTPTLALLAEREAAISGFQKEKFYTVELELEGFRAASERFASKTDAGRLR  240
            QGKSLNVGRVQTPTLALLAEREAAISGFQKEKFYTVELELEGFRAASERFASKTDAGRLR
Sbjct  181  QGKSLNVGRVQTPTLALLAEREAAISGFQKEKFYTVELELEGFRAASERFASKTDAGRLR  240

Query  241  TGCVGKPATVQTVSQKEKTERPPKLYDLTTLQREANRLFDYTAQQTLDYLQALYEKRLAT  300
            TGCVGKPATVQTVSQKEKTERPPKLYDLTTLQREANRLFDYTAQQTLDYLQALYEKRLAT
Sbjct  241  TGCVGKPATVQTVSQKEKTERPPKLYDLTTLQREANRLFDYTAQQTLDYLQALYEKRLAT  300

Query  301  YPRTDSRYLTEDMAAGLPALCQSVAAALPFAADLSLPVNAAQVIDNSKVTDHHAILPTTE  360
            YPRTDSRYLTEDMAAGLPALCQSVAAALPFAADLSLPVNAAQVIDNSKVTDHHAILPTTE
Sbjct  301  YPRTDSRYLTEDMAAGLPALCQSVAAALPFAADLSLPVNAAQVIDNSKVTDHHAILPTTE  360

Query  361  AAKTDLSALPSGEKNILFLVAARLLCAVGEPHTYAETAVTLECGGAVFSAKGKTETAAGW  420
            AAKTDLSALPSGEKNILFLVAARLLCAVGEPHTYAETAVTLECGGAVFSAKGKTETAAGW
Sbjct  361  AAKTDLSALPSGEKNILFLVAARLLCAVGEPHTYAETAVTLECGGAVFSAKGKTETAAGW  420

Query  421  TAMEQAFHATlkkkpkqpepspplpaltkGQKLTAGGASIKEGATSPPAHFTEDTLLSAM  480
            TAMEQAFHATLKKKPKQPEPSPPLPALTKGQKLTAGGASIKEGATSPPAHFTEDTLLSAM
Sbjct  421  TAMEQAFHATLKKKPKQPEPSPPLPALTKGQKLTAGGASIKEGATSPPAHFTEDTLLSAM  480

Query  481  EHASAKEFAKLEDVEHKGLGTPATRAGVIEKLVRSGFVERKKKQLFPTEKGTELIKVMPD  540
            EHASAKEFAKLEDVEHKGLGTPATRAGVIEKLVRSGFVERKKKQLFPTEKGTELIKVMPD
Sbjct  481  EHASAKEFAKLEDVEHKGLGTPATRAGVIEKLVRSGFVERKKKQLFPTEKGTELIKVMPD  540

Query  541  TLKSVKLTAEWEERLGAVERGELSPEDFMAGITAMLTELVKSYQGVTVASAALSASGRTV  600
            TLKSVKLTAEWEERLGAVERGELSPEDFMAGITAMLTELVKSYQGVTVASAALSASGRTV
Sbjct  541  TLKSVKLTAEWEERLGAVERGELSPEDFMAGITAMLTELVKSYQGVTVASAALSASGRTV  600

Query  601  IGICPRCGKNVVEGKKSFFCEGWNAAPACDFALWKNDRFFTSKHKELTRkaaaallkkGR  660
            IGICPRCGKNVVEGKKSFFCEGWNAAPACDFALWKNDRFFTSKHKELTRKAAAALLKKGR
Sbjct  601  IGICPRCGKNVVEGKKSFFCEGWNAAPACDFALWKNDRFFTSKHKELTRKAAAALLKKGR  660

Query  661  VAMTGLFSEKKGVLYDAIVVMEDTGEKFVRFKLEFDNNTPKKKGN  705
            VAMTGLFSEKKGVLYDAIVVMEDTGEKFVRFKLEFDNNTPKKKGN
Sbjct  661  VAMTGLFSEKKGVLYDAIVVMEDTGEKFVRFKLEFDNNTPKKKGN  705

2) CLS_04840 in NC_021047


> NC_004668_R1|30|G30|29376814|NP_815968.1|Enterococcus_faecalis_V583|-|30310..32427|topB-2|EF2312|DNA 
topoisomerase III
Length=705

 Score =  714 bits (2702),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 406/703 (58%), Positives = 540/703 (77%), Gaps = 14/703 (1%)

Query  1    MRLVIAEKPSVAKSLATVLGAATRKDGYLEGNGWLVSWCLGHLAGLADAATYNPDYAKWR  60
            M+LVIAEKPSV+ +L+ VLGA +R DGY+EG GWLVSWC+GHL  LA A +Y+P Y+KW 
Sbjct  1    MQLVIAEKPSVGMALSKVLGAKSRGDGYMEGGGWLVSWCIGHLVELAPADAYDPRYSKWN  60

Query  61   YDDLPILPETWRFTIAKDKRDQFDVLRTLLRREDVTEVVNACDAGREGELIFRTVYCLAG  120
            Y DLPILP  W+F +  D + QF+VL+TL++R DVT ++ A DAGREGELIFR  Y L G
Sbjct  61   YADLPILPKPWQFQVLPDTKKQFEVLKTLIHRADVTALICATDAGREGELIFRLTYHLCG  120

Query  121  CQKPMKRLWISSMEDSAIREGFAHLRPGADYDGLHQAALCRAKADWLVGINATRLFSVLY  180
            C KP+KRLWISSME++AI+ GF +L  G +YD L  AALCRAKADWL+GIN+TRLF+ LY
Sbjct  121  CTKPVKRLWISSMEEAAIQKGFDNLLDGKNYDNLYAAALCRAKADWLIGINGTRLFTTLY  180

Query  181  H-RTLNIGRVMSPTLALIVQREAEIDAFKPVPFYTVALDLPGFTAASARMDKKADAEQLK  239
            + ++LN+GRV +PTLAL+ +REA I +F+   FYTV L+L GF AAS R   K+DA +L+
Sbjct  181  QGKSLNVGRVQTPTLALLAEREAAISGFQKEKFYTVELELEGFRAASERFASKTDAGRLR  240

Query  240  NACQSGTVTVKQVARRDKSEKPPALYDLTTLQRDANRLLGFTAQQTLDYLQNLYEKKLCT  299
             +C +   TV+ V++++K+E+PP LYDLTTLQR+ANRL+++TAQQTLDYLQ LYEK+L T
Sbjct  241  TGCVGKPATVQTVSQKEKTERPPKLYDLTTLQREANRLFDYTAQQTLDYLQALYEKRLAT  300

Query  300  YPRTDSRYLTSDMAEGLPVLVNLVANAMPFRKGIAISCDAAAVINDKKVTDHHAVIPTRN  359
            YPRTDSRYLT DMA GLP L + VA A+PF  +++++ +AA VI++ KVTDHHA++PT +
Sbjct  301  YPRTDSRYLTEDMAAGLPALCQSVAAALPFAADLSLPVNAAQVIDNSKVTDHHAILPTTE  360

Query  360  IREADLSALPVGERAILELVALRLLCAVAHPYIYDETSVTVECAGAEFTAKGRTVKQPGW  419
               +DLSALP GE+ IL LVA RLLCAV++P  Y ET+VT+EC+GA F+AKG+T   +GW
Sbjct  361  AAKTDLSALPSGEKNILFLVAARLLCAVGEPHTYAETAVTLECGGAVFSAKGKTETAAGW  420

Query  420  RALDAAYRASMKNAEPDKETEDKALPELAEGQELPVAGAAVKEGKTTPPKHFTEDTLLSA  479
             A++ A++A++K+  P +     +LP L+ GQ L  +GA++KEG T+PP HFTEDTLLSA
Sbjct  421  TAMEQAFHATLKK-KPKQPEPSPPLPALTKGQKLTAGGASIKEGATSPPAHFTEDTLLSA  479

Query  480  METAGAKDMP--EDAERKGLGTPATRAGILEKLVSTGFLERKKSKKTVQLLPSHDAISLI  537
            ME A+AK+ +  ED E+KGLGTPATRAG++EKLV +GF+ERKK     QL+P++ +  LI
Sbjct  480  MEHASAKEFAKLEDVEHKGLGTPATRAGVIEKLVRSGFVERKKK----QLFPTEKGTELI  535

Query  538  TVLPEQLQSPLLTAEWEYRLGEIERGELAPEDFMAEITAMLKELVGTYQVIK-GSEYLFA  596
             V+P+ L+S  LTAEWE RLG +ERGEL+PEDFMA ITAML ELV +YQ +  +S  L A
Sbjct  536  KVMPDTLKSVKLTAEWEERLGAVERGELSPEDFMAGITAMLTELVKSYQGVTVASAALSA  595

Query  597  PPREVVGKCPRCGGEIAEMQKGFFCQD----KSCKFAIWKNSKWWAAKRKQPTKAIVAAL  652
            + R V+G CPRCG ++ E +K+FFC++     +C FA+WKN +  ++K+K+ T+   AAL
Sbjct  596  SGRTVIGICPRCGKNVVEGKKSFFCEGWNAAPACDFALWKNDRFFTSKHKELTRKAAAAL  655

Query  653  LKDGRARVTGLYSEKSGKTYDATVVLEDTGQ-YVNFKLEFDRQ  694
            LK GR  +TGL+SEK G  YDA VV+EDTG+ +V FKLEFD +
Sbjct  656  LKKGRVAMTGLFSEKKGVLYDAIVVMEDTGEKFVRFKLEFDNN  698

3) FP2_09300 in NC_021042


> NC_004668_R1|30|G30|29376814|NP_815968.1|Enterococcus_faecalis_V583|-|30310..32427|topB-2|EF2312|DNA 
topoisomerase III
Length=705

 Score =  668 bits (2525),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 387/706 (55%), Positives = 519/706 (74%), Gaps = 19/706 (2%)

Query  1    MKLVLAEKPSVAQSIAKVLGAAKREDGYLEGNGYVVSWCVGHLVELAQPEVYDAKYSKWA  60
            M+LV+AEKPSV+ +++KVLGA  R DGY+EG G +VSWC+GHLVELA ++ YD++YSKW 
Sbjct  1    MQLVIAEKPSVGMALSKVLGAKSRGDGYMEGGGWLVSWCIGHLVELAPADAYDPRYSKWN  60

Query  61   YADLPIFPMDWQYEVSAGTKKQFGILKKLMAREDVASLVCATDAGREGELIFRLVYHKAG  120
            YADLPI+P  WQ++V ++TKKQF +LK L+ R DV++L+CATDAGREGELIFRL YH  G
Sbjct  61   YADLPILPKPWQFQVLPDTKKQFEVLKTLIHRADVTALICATDAGREGELIFRLTYHLCG  120

Query  121  CRKPFERLWISSMEDVAIKEGFENLRSGTEYDALYEAALCRERADWIVGINATRLFSTLY  180
            C KP  RLWISSME+ AI+ GF+NL  G +YD LY AALCR +ADW++GIN+TRLF+TLY
Sbjct  121  CTKPVKRLWISSMEEAAIQKGFDNLLDGKNYDNLYAAALCRAKADWLIGINGTRLFTTLY  180

Query  181  -GQTLNVGRVMTPTLAMAVMREAAISAFKPELFYTVQIGLDGFTAASERFKTKAAAEAVK  239
             G++LNVGRV TPTLA+   REAAIS+F+ E FYTV++ L+GF AASERF +K+ A  ++
Sbjct  181  QGKSLNVGRVQTPTLALLAEREAAISGFQKEKFYTVELELEGFRAASERFASKTDAGRLR  240

Query  240  QSC--SVAIVQKAECKEKTEKPPALYDLTSLQREANRVLGYTAQQTLDYTQNLYEKKLVT  297
             +C    A VQ    KEKTE+PP LYDLT+LQREANR+++YTAQQTLDY Q LYEK+L T
Sbjct  241  TGCVGKPATVQTVSQKEKTERPPKLYDLTTLQREANRLFDYTAQQTLDYLQALYEKRLAT  300

Query  298  YPRTDSRFLTEDMAHSLTDLVKLAFHTFPVEDVDNIPVHAEQVVNNKKVTDHHAIIPTRE  357
            YPRTDSR+LTEDMA +L  L +    ++P     ++PV+A QV++N KVTDHHAI+PT E
Sbjct  301  YPRTDSRYLTEDMAAGLPALCQSVAAALPFAADLSLPVNAAQVIDNSKVTDHHAILPTTE  360

Query  358  LQKCNLSELPKGELAILQLISNRLCVAVGDPHRYAETVIELDCGGTVFSTKGKTVVQDGW  417
              K +LS LP GE  IL L++ RL  AVG+PH YAET + L+CGG+VFS+KGKT    GW
Sbjct  361  AAKTDLSALPSGEKNILFLVAARLLCAVGEPHTYAETAVTLECGGAVFSAKGKTETAAGW  420

Query  418  KALVQKNDST-----KSDENVQTLPSVSVGDEMTVSGTEIKEGKTSPPKHFTEDTLLSAM  472
             A+ Q  ++T     K  E    LP+++ G+ +T +G+ IKEG TSPP HFTEDTLLSAM
Sbjct  421  TAMEQAFHATLKKKPKQPEPSPPLPALTKGQKLTAGGASIKEGATSPPAHFTEDTLLSAM  480

Query  473  ETAGADEMP--DEVERKGLGTPATRAGIIEKLVRIGFLERKGDKKTKHLIPTHKGTALVT  530
            E A+A E +  ++VE+KGLGTPATRAG+IEKLVR GF+ER    K K+L+PT+KGT L+ 
Sbjct  481  EHASAKEFAKLEDVEHKGLGTPATRAGVIEKLVRSGFVER----KKKQLFPTEKGTELIK  536

Query  531  VMPEQIQSPSMTADWEEKLLLIEKGEYASEDFMDEIKDVIAGLIQNYEVIRDSEVMMSKE  590
            VMP+ ++S  +TA+WEE+L  +E+GE ++EDFM  I  +++ L+++Y+ +  +   +S  
Sbjct  537  VMPDTLKSVKLTAEWEERLGAVERGELSPEDFMAGITAMLTELVKSYQGVTVASAALSAS  596

Query  591  ANS-IGKCPLCGSAVEDKAKAFFCSNR----ACKFALWKNNRYFASIGKSMTSATAQKLL  645
            + + IG CP CG  V +  K+FFC  +    AC FALWKN+R+F+S  K +T  +A  LL
Sbjct  597  GRTVIGICPRCGKNVVEGKKSFFCEGWNAAPACDFALWKNDRFFTSKHKELTRKAAAALL  656

Query  646  GSGKVKLKNCKSERTGNTFDATVFMEVSDDGKTKFSMEFENGGKRK  691
              G+V +    SE+ G  +DA V ME +++   +F +EF+N   +K
Sbjct  657  KKGRVAMTGLFSEKKGVLYDAIVVMEDTGEKFVRFKLEFDNNTPKK  702

4) topB in NC_016048


> NC_004668_R1|30|G30|29376814|NP_815968.1|Enterococcus_faecalis_V583|-|30310..32427|topB-2|EF2312|DNA 
topoisomerase III
Length=705

 Score =  663 bits (2506),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 397/702 (57%), Positives = 551/702 (79%), Gaps = 27/702 (3%)

Query  1    MKLVIAEKPSVAQSIAAVLGAKQRGGGYLEGSGWLVSWCFGHLAELASAESYNPEYAKWK  60
            M+LVIAEKPSV+ +++ VLGAK RG+GY+EG+GWLVSWC+GHL ELA+A++Y+P Y+KW+
Sbjct  1    MQLVIAEKPSVGMALSKVLGAKSRGDGYMEGGGWLVSWCIGHLVELAPADAYDPRYSKWN  60

Query  61   YDDLPIVPETWRFKVSRDKWQQFDILKKLMHSEDVSEVVNACDAGREGELIFRTAYCLAG  120
            Y DLPI+P  W+F+V  D  +QF++LK L+H  DV+ ++ A DAGREGELIFR +Y L G
Sbjct  61   YADLPILPKPWQFQVLPDTKKQFEVLKTLIHRADVTALICATDAGREGELIFRLTYHLCG  120

Query  121  CSKPMKRLWISSMEDSAIRDGFAHLRPGSDYDGLHQSALCRSKADWLVGINATRLFSVLY  180
            C+KP+KRLWISSME++AI+ GF +L  G +YD L  +ALCR+KADWL+GIN+TRLF+ LY
Sbjct  121  CTKPVKRLWISSMEEAAIQKGFDNLLDGKNYDNLYAAALCRAKADWLIGINGTRLFTTLY  180

Query  181  H-RTLNVGRVMSPTLALIVQREAEIDAFRAEPFYTVELDV-GFPAVSEKFREESqakava  238
            + ++LNVGRV +PTLAL+ +REA I +F+ E FYTVEL++ GF A SE+F   ++A  + 
Sbjct  181  QGKSLNVGRVQTPTLALLAEREAAISGFQKEKFYTVELELEGFRAASERFASKTDAGRLR  240

Query  239  aacqgqpaavksverkeksekAPALYDLTTLQRNANRLLGYTAQQTLDYLQSLYEKKLCT  298
            ++C G+PA+V++V +KEK+E++P LYDLTTLQR+ANRL++YTAQQTLDYLQ+LYEK+L T
Sbjct  241  TGCVGKPATVQTVSQKEKTERPPKLYDLTTLQREANRLFDYTAQQTLDYLQALYEKRLAT  300

Query  299  YPRTDARFLTDDMEGSVPAL-VSVAATL-YEAAAPGKIGAAQICDSKNVSDHHALVPTVS  356
            YPRTD+R+LT+DM +++PAL  SVAA+L + A  +  + AAQ+ D+ +V+DHHA++PT  
Sbjct  301  YPRTDSRYLTEDMAAGLPALCQSVAAALPFAADLSLPVNAAQVIDNSKVTDHHAILPTTE  360

Query  357  AGKAALSALPAGERKILRLVSRQLLCAVSEACRYAETVAAVECGGSVFTAKGRTVLAPGW  416
            A+K+ LSALP+GE++IL LV+ +LLCAV+E+  YAET  ++ECGG+VF+AKG+T  A+GW
Sbjct  361  AAKTDLSALPSGEKNILFLVAARLLCAVGEPHTYAETAVTLECGGAVFSAKGKTETAAGW  420

Query  417  -----------KNYIQQEQPEKPLPDLTDGQALTVSGISTKEGKMTPPKHYTEDTLLSAM  465
                       K+  +Q +P  PLP LT GQ LT +G S KEG  +PP H+TEDTLLSAM
Sbjct  421  TAMEQAFHATLKKKPKQPEPSPPLPALTKGQKLTAGGASIKEGATSPPAHFTEDTLLSAM  480

Query  466  EVAGAKETP--DDAERKGLGTPATRAAILEKLVSTGFVERKKAKKTVSLMPSHTGVSLIT  523
            E A+AKE +  +D E+KGLGTPATRA+++EKLV +GFVERKK +    L P++ G  LI 
Sbjct  481  EHASAKEFAKLEDVEHKGLGTPATRAGVIEKLVRSGFVERKKKQ----LFPTEKGTELIK  536

Query  524  VLPEQLQSPLLTAEWEQKLKQVERGELTADAFLDGITAMLRELVKTYKAIK-GAEVLFPS  582
            V+P+ L+S  LTAEWE++L  VERGEL+++ F+ GITAML ELVK+Y+++  ++  L +S
Sbjct  537  VMPDTLKSVKLTAEWEERLGAVERGELSPEDFMAGITAMLTELVKSYQGVTVASAALSAS  596

Query  583  GREVVGKCPRCGGDVTESKKGFFCE----SADCRFGLWRDNKFLTAKRAVLDKKAVTALL  638
            GR V+G CPRCG +V E+KK+FFCE    ++ C F+LW++++F+T+K+  L +KA +ALL
Sbjct  597  GRTVIGICPRCGKNVVEGKKSFFCEGWNAAPACDFALWKNDRFFTSKHKELTRKAAAALL  656

Query  639  KTGRVAMTGLYSEKTGKTYDATLVLEDDGQR-ANFKLEFNHG  679
            K GRVAMTGL+SEK G  YDA +V+ED G++   FKLEF++ 
Sbjct  657  KKGRVAMTGLFSEKKGVLYDAIVVMEDTGEKFVRFKLEFDNN  698

5) CK5_29340 in NC_021022


> NC_004668_R1|30|G30|29376814|NP_815968.1|Enterococcus_faecalis_V583|-|30310..32427|topB-2|EF2312|DNA 
topoisomerase III
Length=705

 Score =  662 bits (2501),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 378/709 (54%), Positives = 520/709 (74%), Gaps = 13/709 (1%)

Query  1    MKLVIAEKPSVAMSLAAVLGATERKDGYLEGSGYLVSWCVGHLLELAQPEAYKEQYAKWR  60
            M+LVIAEKPSV+M+L+ VLGA  R DGY+EG+G LVSWC+GHL+ELA ++AY  +Y+KW 
Sbjct  1    MQLVIAEKPSVGMALSKVLGAKSRGDGYMEGGGWLVSWCIGHLVELAPADAYDPRYSKWN  60

Query  61   YEDLPILPENWKYEVPKDKKTQLALLCRLMKDKRVDSVVCATDAGREGELIFRLVYEYAG  120
            Y DLPILP  W+++V  D K Q+ +L  L+    V +++CATDAGREGELIFRL Y+  G
Sbjct  61   YADLPILPKPWQFQVLPDTKKQFEVLKTLIHRADVTALICATDAGREGELIFRLTYHLCG  120

Query  121  CKKPMERLWISSMEDAAIREGFDHLHPGSDYDKLYDAAVCRAGADWLIGINATRLFSVLY  180
            C KP+ RLWISSME+AAI+ GFD+L  G +YD+LY AA+CRA ADWLIGIN+TRLF+ LY
Sbjct  121  CTKPVKRLWISSMEEAAIQKGFDNLLDGKNYDNLYAAALCRAKADWLIGINGTRLFTTLY  180

Query  181  -GVTLNVGRVMSPTLALLVQRESDIESFISKPFYVPEITCGGFTASGEKMTERSEAEKIR  239
             G +LNVGRV +PTLALL +RE+ I +F    FY  E+   GF A++E+ + +++A ++R
Sbjct  181  QGKSLNVGRVQTPTLALLAEREAAISGFQKEKFYTVELELEGFRAASERFASKTDAGRLR  240

Query  240  MDCDHNSAFVRSVEKQVKTIQPPRLYDLTTLQRECNRIYGYTAQQTLDYVQSLYEKKLAT  299
             +C  ++A V++V ++ KT +PP+LYDLTTLQRE NR+++YTAQQTLDY+Q+LYEK+LAT
Sbjct  241  TGCVGKPATVQTVSQKEKTERPPKLYDLTTLQREANRLFDYTAQQTLDYLQALYEKRLAT  300

Query  300  YPRTDSQYLTKDMQATAASLILWLRDNMTFGKGYAGEPDIDRVTDDSKVTDHHAIIPTVE  359
            YPRTDS+YLT DM A  ++L   +   + F+ + +   +  +V D+SKVTDHHAI+PT E
Sbjct  301  YPRTDSRYLTEDMAAGLPALCQSVAAALPFAADLSLPVNAAQVIDNSKVTDHHAILPTTE  360

Query  360  IARTDLSELPSGERDVLTLLAVRLLCATTQVHRFEAVTAILDCQGYTFTAKGKTILQSGW  419
             A+TDLS LPSGE+++L L+A RLLCA  + H +   +  L+C G  F+AKGKT   +GW
Sbjct  361  AAKTDLSALPSGEKNILFLVAARLLCAVGEPHTYAETAVTLECGGAVFSAKGKTETAAGW  420

Query  420  KEVERIHRMSIRQSETERRENEDAALPVLKEGQTFETVSASLREGKTSPPKHYTEDTLLS  479
              +E+  + ++++    ++ +  ++LP L  GQ + + +AS++EG TSPP H+TEDTLLS
Sbjct  421  TAMEQAFHATLKK--KPKQPEPSPPLPALTKGQKLTAGGASIKEGATSPPAHFTEDTLLS  478

Query  480  AMETAGAEDMP--EDAERKGLGTPATRAATLEKLVSAGFVQRKKKQLIPTEKGKNLIAVL  537
            AME A+A + +  ED E+KGLGTPATRA+ +EKLV +GFV+RKKKQL+PTEKG +LI V+
Sbjct  479  AMEHASAKEFAKLEDVEHKGLGTPATRAGVIEKLVRSGFVERKKKQLFPTEKGTELIKVM  538

Query  538  PDNIKSPILTAEWESMLKQVEHGELSATSFMDQIADMSRTLVKEHTTPEERFADLFPSSK  597
            PD +KS  LTAEWE  L  VE+GELS+  FM  I+ M   LVK         A L     
Sbjct  539  PDTLKSVKLTAEWEERLGAVERGELSPEDFMAGITAMLTELVKSYQGVTVASAAL----S  594

Query  598  GTAHEAVGVCPRCGAPVFEGKKGFFCGNRE----CSFALWKDNRFFsskkksitksVAAA  653
            ++++  +G+CPRCG  V EGKK+FFC  ++    C FALWK++RFF+SK K +T+  AAA
Sbjct  595  ASGRTVIGICPRCGKNVVEGKKSFFCEGWNAAPACDFALWKNDRFFTSKHKELTRKAAAA  654

Query  654  LLKEGRISMSGLYSEKTGRTYDAEVILDDTGGKYVNFKLEFPVKKGRRK  702
            LLK GR++M+GL+SEK G  YDA V+++DTG K+V FKLEF  +  ++K
Sbjct  655  LLKKGRVAMTGLFSEKKGVLYDAIVVMEDTGEKFVRFKLEFDNNTPKKK  703

6) Ethha_1903 in NC_014828


> NC_004668_R1|30|G30|29376814|NP_815968.1|Enterococcus_faecalis_V583|-|30310..32427|topB-2|EF2312|DNA 
topoisomerase III
Length=705

 Score =  657 bits (2484),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 398/709 (57%), Positives = 549/709 (78%), Gaps = 27/709 (3%)

Query  1    MRFVISEKPSVAQSIAAVIGAKQRGDGFLEGNGYLVSWCLGHLAELASADAYDEKYAKWR  60
            M++VI+EKPSV+ +++ V+GAK RGDG++EG G LVSWC+GHL ELA+ADAYD +Y+KW 
Sbjct  1    MQLVIAEKPSVGMALSKVLGAKSRGDGYMEGGGWLVSWCIGHLVELAPADAYDPRYSKWN  60

Query  61   REDLPILPENWRFTVSGDKQKQFAILRTLMRRDDVDEVINACDAGREGELIFRTVYDMAG  120
              DLPILP  W+F V  D +KQF +L+TL++R DV  +I A DAGREGELIFR  Y++ G
Sbjct  61   YADLPILPKPWQFQVLPDTKKQFEVLKTLIHRADVTALICATDAGREGELIFRLTYHLCG  120

Query  121  CSKPMKRLWISSMEDEAIRQGFADLKPGRDYDGLHQSALCRSKADWLVGINATRLFSALY  180
            C+KP+KRLWISSME+ AI++GF +L  G++YD L  +ALCR+KADWL+GIN+TRLF++LY
Sbjct  121  CTKPVKRLWISSMEEAAIQKGFDNLLDGKNYDNLYAAALCRAKADWLIGINGTRLFTTLY  180

Query  181  H-RTLNVGRVMSPTLALLVQREAEISAFQPEPFYTVSLDCGTFTAIGDKLKTKSEAEAVA  239
            + ++LNVGRV +PTLALL +REA IS+FQ E FYTV L+   F A ++++ +K++A  + 
Sbjct  181  QGKSLNVGRVQTPTLALLAEREAAISGFQKEKFYTVELELEGFRAASERFASKTDAGRLR  240

Query  240  AACKGKTATVRAVERKEKSEKPPALYDLTTLQRDANRLLGYTAQQTLDYLQSLYEKKLCT  299
            ++C GK ATV++V +KEK+E+PP LYDLTTLQR+ANRL++YTAQQTLDYLQ+LYEK+L T
Sbjct  241  TGCVGKPATVQTVSQKEKTERPPKLYDLTTLQREANRLFDYTAQQTLDYLQALYEKRLAT  300

Query  300  YPRTDSRFLTNDMKasvpa--fasvaaaICGTDVPESLNAGQVCDSAKVSDHHAVVPTSG  357
            YPRTDSR+LT+DM A++PA   +  AA   ++D++ ++NA+QV D++KV+DHHA++PT+ 
Sbjct  301  YPRTDSRYLTEDMAAGLPALCQSVAAALPFAADLSLPVNAAQVIDNSKVTDHHAILPTTE  360

Query  358  AGKADVSALPAGEREILRLVSRQLLCAVGSPHQYAETAVTLDCTGYGFAAKGKTVLVPGW  417
            A+K+D+SALP+GE++IL LV+ +LLCAVG PH YAETAVTL+C G  F+AKGKT   +GW
Sbjct  361  AAKTDLSALPSGEKNILFLVAARLLCAVGEPHTYAETAVTLECGGAVFSAKGKTETAAGW  420

Query  418  KS---CFQE---------QADKPLPELAEGQDIAVASVSVKEGKTSPPKHYTEDTLLSAM  465
             +    F+          ++  PLP L+ GQ ++ ++ S+KEG TSPP H+TEDTLLSAM
Sbjct  421  TAMEQAFHATLKKKPKQPEPSPPLPALTKGQKLTAGGASIKEGATSPPAHFTEDTLLSAM  480

Query  466  ETAGAKDMP--DDAERKGLGTPATRAAILEKLVTTGFVERKKAKKTVNLIPSQVGVSLVT  523
            E A+AK+ +  +D E+KGLGTPATRA+++EKLV +GFVERKK     +L+P++ G  L+ 
Sbjct  481  EHASAKEFAKLEDVEHKGLGTPATRAGVIEKLVRSGFVERKKK----QLFPTEKGTELIK  536

Query  524  VLPEQLQSPLLTAEWENRLKQVEHGKLEPDAFMNGISSMLRELIKTYTPVK-GAEVLFPS  582
            V+P+ L+S  LTAEWE+RL  VE+G L P+ FM GI++ML EL+K+Y  V  ++  L +S
Sbjct  537  VMPDTLKSVKLTAEWEERLGAVERGELSPEDFMAGITAMLTELVKSYQGVTVASAALSAS  596

Query  583  GREAVGKCPRCGGSVTESKKGFFCE----NDGCRFGLWKDNRffaakkkvltkavaaafl  638
            GR  +G CPRCG +V E+KK+FFCE      +C F+LWK++RFF++K K LT+  AAA+L
Sbjct  597  GRTVIGICPRCGKNVVEGKKSFFCEGWNAAPACDFALWKNDRFFTSKHKELTRKAAAALL  656

Query  639  kDGRVRLTGCYSEKTGKTYDATVILEDTGGR-VNFKLEFDSGTKKRGGS  686
            K GRV +TG +SEK G  YDA V++EDTG + V FKLEFD+ T K+ G+
Sbjct  657  KKGRVAMTGLFSEKKGVLYDAIVVMEDTGEKFVRFKLEFDNNTPKKKGN  705

7) EUR_07600 in NC_021010


> NC_004668_R1|30|G30|29376814|NP_815968.1|Enterococcus_faecalis_V583|-|30310..32427|topB-2|EF2312|DNA 
topoisomerase III
Length=705

 Score =  655 bits (2476),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 389/701 (56%), Positives = 534/701 (77%), Gaps = 14/701 (1%)

Query  5    KLVIAEKPSVAQSLAAVIGATVRKDGYLEGNGWRVSWCVGHLAGLADADSYDPKYAKWRY  64
            +LVIAEKPSV+ +L+ V+GA  R DGY+EG GW VSWC+GHL  LA AD+YDP+Y+KW Y
Sbjct  2    QLVIAEKPSVGMALSKVLGAKSRGDGYMEGGGWLVSWCIGHLVELAPADAYDPRYSKWNY  61

Query  65   DDLPILPEHWQMVVGkdkkkqfdilkklMNAPDVTEVVNACDAGREGEMIFRSVYKLAGC  124
             DLPILP  WQ  V  D KKQF++LK L++ +DVT ++ A DAGREGE+IFR  Y L GC
Sbjct  62   ADLPILPKPWQFQVLPDTKKQFEVLKTLIHRADVTALICATDAGREGELIFRLTYHLCGC  121

Query  125  KKPMKRLWISSMEDSAIREGFANLRPSADYDGLRDAALCRAKADWLVGINATRLFSVLYH  184
             KP+KRLWISSME++AI+ GF NL  + +YD L  AALCRAKADWL+GIN+TRLF+ LY+
Sbjct  122  TKPVKRLWISSMEEAAIQKGFDNLLDGKNYDNLYAAALCRAKADWLIGINGTRLFTTLYQ  181

Query  185  -RTLNIGRVMSPTLALIVQREAEIDTFKPIPFYTVALELPGLTVSGERMANKAAAEQLKE  243
             ++LN+GRV +PTLAL+ +REA I  F+   FYTV LEL G+  ++ER A+K+ A +L+ 
Sbjct  182  GKSLNVGRVQTPTLALLAEREAAISGFQKEKFYTVELELEGFRAASERFASKTDAGRLRT  241

Query  244  ACQGANVTIKKVECKEKSEKPPALYDLTTLQRDANRLLGFTAQQTLDYLQSLYEKKLCTY  303
            +C G   T++ V  KEK+E+PP LYDLTTLQR+ANRL+++TAQQTLDYLQ+LYEK+L TY
Sbjct  242  GCVGKPATVQTVSQKEKTERPPKLYDLTTLQREANRLFDYTAQQTLDYLQALYEKRLATY  301

Query  304  PRTDSRYLTGDMADSLPVLVNLVASAMPFRKGIAITCDPHTVINDKKVTDHHAVIPTRNL  363
            PRTDSRYLT DMA +LP L + VA+A+PF  ++++  ++  VI++ KVTDHHA++PT + 
Sbjct  302  PRTDSRYLTEDMAAGLPALCQSVAAALPFAADLSLPVNAAQVIDNSKVTDHHAILPTTEA  361

Query  364  KDADLSALPAGEKAVLELVALRLMCAVAQPHIYSETVVIAACAGGEFTTKGKTVKHPGWK  423
              +DLSALP+GEK +L LVA RL+CAV++PH Y+ET V   C+G+ F++KGKT   +GW 
Sbjct  362  AKTDLSALPSGEKNILFLVAARLLCAVGEPHTYAETAVTLECGGAVFSAKGKTETAAGWT  421

Query  424  ALEDAYRAKMKNAEPKKEGAEKALPELTEGQTLSVAAAIVKEGKSSPPQHFTEDTLLSAM  483
            A+E+A++A +K+  PK+  +  +LP LT GQ L+ ++A +KEG +SPP HFTEDTLLSAM
Sbjct  422  AMEQAFHATLKK-KPKQPEPSPPLPALTKGQKLTAGGASIKEGATSPPAHFTEDTLLSAM  480

Query  484  ETAGKENMP--EDAERKGLGTPATRAGILEKLVSAGFLERKKNRKTVQLLPSHDAVSLIT  541
            E A+  + +  ED E+KGLGTPATRAG++EKLV +GF+ERKK+    QL+P++ +  LI 
Sbjct  481  EHASAKEFAKLEDVEHKGLGTPATRAGVIEKLVRSGFVERKKK----QLFPTEKGTELIK  536

Query  542  VLPEQLQSPLLTAEWEYRLGEIERGQLAPEEFLDGISTMLKDLVGTYQVIK-GTEYLFTP  600
            V+P+ L+S  LTAEWE RLG +ERG+L+PE+F+ GI++ML +LV +YQ +  ++  L ++
Sbjct  537  VMPDTLKSVKLTAEWEERLGAVERGELSPEDFMAGITAMLTELVKSYQGVTVASAALSAS  596

Query  601  PREVVGKCPRCGGEVAELQKGFFCQN----DSCKFAIwknnkwwaakkkQPTKAVVSALL  656
             R V+G CPRCG +V E +K+FFC+      +C FA+WKN++  ++K K+ T+   +ALL
Sbjct  597  GRTVIGICPRCGKNVVEGKKSFFCEGWNAAPACDFALWKNDRFFTSKHKELTRKAAAALL  656

Query  657  NDGRVRVTGLYSEKTGKTYDATVVLEDDGQ-YANFKLEFDQ  696
            + GRV +TGL+SEK G  YDA VV+ED G+ +  FKLEFD+
Sbjct  657  KKGRVAMTGLFSEKKGVLYDAIVVMEDTGEKFVRFKLEFDN  697

8) EC1_10280 in NC_021019


> NC_004668_R1|30|G30|29376814|NP_815968.1|Enterococcus_faecalis_V583|-|30310..32427|topB-2|EF2312|DNA 
topoisomerase III
Length=705

 Score =  652 bits (2466),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 389/702 (56%), Positives = 533/702 (76%), Gaps = 14/702 (1%)

Query  1    MNLVIAEKPSVAQSLAAVIGATVRKDGYLEGNGWRVSWCVGHLAGLADADSYDQKYAKWR  60
            M+LVIAEKPSV+ +L+ V+GA  R DGY+EG GW VSWC+GHL  LA AD+YD +Y+KW 
Sbjct  1    MQLVIAEKPSVGMALSKVLGAKSRGDGYMEGGGWLVSWCIGHLVELAPADAYDPRYSKWN  60

Query  61   YDDLPILPEHWQMVVGkdkkkqfdilkklMNAPDMTEVVNACDAGREGEMIFRSVYELAG  120
            Y DLPILP  WQ  V  D KKQF++LK L++ +D+T ++ A DAGREGE+IFR  Y+L G
Sbjct  61   YADLPILPKPWQFQVLPDTKKQFEVLKTLIHRADVTALICATDAGREGELIFRLTYHLCG  120

Query  121  CKKPMKRLWISSMEDSAIREGFANLRPSADYDGLRDAALCRAKADWLVGINATRLFSVLY  180
            C KP+KRLWISSME++AI+ GF NL  + +YD L  AALCRAKADWL+GIN+TRLF+ LY
Sbjct  121  CTKPVKRLWISSMEEAAIQKGFDNLLDGKNYDNLYAAALCRAKADWLIGINGTRLFTTLY  180

Query  181  H-RTLNIGRVMSPTLALIVQREAEIDTFKPIPFYTVALELPGLTVSGERVANKAAAEQLK  239
            + ++LN+GRV +PTLAL+ +REA I  F+   FYTV LEL G+  ++ER A+K+ A +L+
Sbjct  181  QGKSLNVGRVQTPTLALLAEREAAISGFQKEKFYTVELELEGFRAASERFASKTDAGRLR  240

Query  240  EACQGANVTIKKVECKEKSEKPPALYDLTTLQRDANRLLGFTAQQTLDYLQSLYEKKLCT  299
             +C G   T++ V  KEK+E+PP LYDLTTLQR+ANRL+++TAQQTLDYLQ+LYEK+L T
Sbjct  241  TGCVGKPATVQTVSQKEKTERPPKLYDLTTLQREANRLFDYTAQQTLDYLQALYEKRLAT  300

Query  300  YPRTDSRYLTGDMADSLPVLVNLVASAMPFRKGIAITCDPHTVINDKKVTDHHAVIPTRN  359
            YPRTDSRYLT DMA +LP L + VA+A+PF  ++++  ++  VI++ KVTDHHA++PT +
Sbjct  301  YPRTDSRYLTEDMAAGLPALCQSVAAALPFAADLSLPVNAAQVIDNSKVTDHHAILPTTE  360

Query  360  LKDADLSALPAGEKAVLELVALRLMCAVAQPHIYSETVVIAACAGGEFTTKGKTVKHPGW  419
               +DLSALP+GEK +L LVA RL+CAV++PH Y+ET V   C+G+ F++KGKT   +GW
Sbjct  361  AAKTDLSALPSGEKNILFLVAARLLCAVGEPHTYAETAVTLECGGAVFSAKGKTETAAGW  420

Query  420  KALEDAYRAKMKDTEPKKEGVEKALPELTEGQTLSVSAAIVKEGKSSPPQHFTEDTLLSA  479
             A+E+A++A +K   PK+     +LP LT GQ L+ ++A +KEG +SPP HFTEDTLLSA
Sbjct  421  TAMEQAFHATLKKK-PKQPEPSPPLPALTKGQKLTAGGASIKEGATSPPAHFTEDTLLSA  479

Query  480  METAGKEDMP--EDAERKGLGTPATRAGILEKLVSAGFLERKKSRKTVQLLPSHDAVSLI  537
            ME A+  + +  ED E+KGLGTPATRAG++EKLV +GF+ERKK     QL+P++ +  LI
Sbjct  480  MEHASAKEFAKLEDVEHKGLGTPATRAGVIEKLVRSGFVERKKK----QLFPTEKGTELI  535

Query  538  TVLPEQLQSPLLTAEWEYRLGEIERGQLAPEEFLAGISTMLKDLVGTYQVIK-GTEYLFT  596
             V+P+ L+S  LTAEWE RLG +ERG+L+PE+F+AGI++ML +LV +YQ +  ++  L +
Sbjct  536  KVMPDTLKSVKLTAEWEERLGAVERGELSPEDFMAGITAMLTELVKSYQGVTVASAALSA  595

Query  597  PLREVVGKCPRCGVEVAELQKGFFCQN----DSCKFAIwknnkwwaakkkQPTKAVVSAL  652
            + R V+G CPRCG +V E +K+FFC+      +C FA+WKN++  ++K K+ T+   +AL
Sbjct  596  SGRTVIGICPRCGKNVVEGKKSFFCEGWNAAPACDFALWKNDRFFTSKHKELTRKAAAAL  655

Query  653  LNDGRVRVTGLYSEKTGKTYDATVVLEDDGQ-YANFKLEFDQ  693
            L+ GRV +TGL+SEK G  YDA VV+ED G+ +  FKLEFD+
Sbjct  656  LKKGRVAMTGLFSEKKGVLYDAIVVMEDTGEKFVRFKLEFDN  697

9) RTO_00720 in NC_021015


> NC_004668_R1|30|G30|29376814|NP_815968.1|Enterococcus_faecalis_V583|-|30310..32427|topB-2|EF2312|DNA 
topoisomerase III
Length=705

 Score =  652 bits (2466),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 392/701 (56%), Positives = 528/701 (76%), Gaps = 14/701 (1%)

Query  5    KLVIAEKPSVAQSLAAVIGATVRKDGYLEGNGWRVSWCVGHLAGLADADSYDPKYAKWRY  64
            +LVIAEKPSV+ +L+ V+GA  R DGY+EG GW VSWC+GHL  LA AD+YDP+Y+KW Y
Sbjct  2    QLVIAEKPSVGMALSKVLGAKSRGDGYMEGGGWLVSWCIGHLVELAPADAYDPRYSKWNY  61

Query  65   DDLPILPEHWQMVVGkdkkkqfdilkklMNAPDVTEVVNACDAGREGELIFRSVYELAGC  124
             DLPILP  WQ  V  D KKQF++LK L++ +DVT ++ A DAGREGELIFR  Y+L GC
Sbjct  62   ADLPILPKPWQFQVLPDTKKQFEVLKTLIHRADVTALICATDAGREGELIFRLTYHLCGC  121

Query  125  KKPMKRLWISSMEDSAIREGFANLRPGADYDGLRDAALCRAKADWLVGINATRLFSVLYH  184
             KP+KRLWISSME++AI+ GF NL  G +YD L  AALCRAKADWL+GIN+TRLF+ LY+
Sbjct  122  TKPVKRLWISSMEEAAIQKGFDNLLDGKNYDNLYAAALCRAKADWLIGINGTRLFTTLYQ  181

Query  185  -RTLNIGRVMSPTLALIVQREAEIDTFQPVPFYTVALELPGLTVSGERMADKAAAKQLKE  243
             ++LN+GRV +PTLAL+ +REA I  FQ   FYTV LEL G+  ++ER A K+ A +L+ 
Sbjct  182  GKSLNVGRVQTPTLALLAEREAAISGFQKEKFYTVELELEGFRAASERFASKTDAGRLRT  241

Query  244  TCRGANVTIKKVECKEKSEKPPALYDLTTLQRDANRLLGFTAQQTLDYLQSLYEKKLCTY  303
             C G   T++ V  KEK+E+PP LYDLTTLQR+ANRL+++TAQQTLDYLQ+LYEK+L TY
Sbjct  242  GCVGKPATVQTVSQKEKTERPPKLYDLTTLQREANRLFDYTAQQTLDYLQALYEKRLATY  301

Query  304  PRTDSRYLTSDMADSLPVLVNLVANAMPFRKGIAITCDPQTVINDKKVTDHHAVIPTRNL  363
            PRTDSRYLT DMA +LP L + VA A+PF  ++++  ++  VI++ KVTDHHA++PT + 
Sbjct  302  PRTDSRYLTEDMAAGLPALCQSVAAALPFAADLSLPVNAAQVIDNSKVTDHHAILPTTEA  361

Query  364  KDADLSALPAGEKAVLELVALRLLCAVAQPHIYSETVVIAACAGGEFTAKGKTVKHPGWK  423
              +DLSALP+GEK +L LVA RLLCAV++PH Y+ET V   C+G+ F+AKGKT   +GW 
Sbjct  362  AKTDLSALPSGEKNILFLVAARLLCAVGEPHTYAETAVTLECGGAVFSAKGKTETAAGWT  421

Query  424  ALEDAYRAKMKDAEPKKEGAEKALPELTEGQTLSVAAAIVKEGKSSPPQHFTEDTLLSAM  483
            A+E+A++A +K   PK+  +  +LP LT GQ L+ ++A +KEG +SPP HFTEDTLLSAM
Sbjct  422  AMEQAFHATLKK-KPKQPEPSPPLPALTKGQKLTAGGASIKEGATSPPAHFTEDTLLSAM  480

Query  484  ETAGKENMP--EEAERKGLGTPATRAGILEKLVSAGFLERKKSRKTVQLLPSHDAVSLIT  541
            E A+  + +  E+ E+KGLGTPATRAG++EKLV +GF+ERKK     QL+P++ +  LI 
Sbjct  481  EHASAKEFAKLEDVEHKGLGTPATRAGVIEKLVRSGFVERKKK----QLFPTEKGTELIK  536

Query  542  VLPEQLQSPLLTAEWEYRLGEIERGQLAPEEFLDGISTMLKDLVGTYQVIK-GTEYLFTP  600
            V+P+ L+S  LTAEWE RLG +ERG+L+PE+F+ GI++ML +LV +YQ +  ++  L ++
Sbjct  537  VMPDTLKSVKLTAEWEERLGAVERGELSPEDFMAGITAMLTELVKSYQGVTVASAALSAS  596

Query  601  PREVVGKCPRCGGEVAELQKGFFCQN----DSCKFAIwknnkwwdakkkQPTKAVVSALL  656
             R V+G CPRCG +V E +K+FFC+      +C FA+WKN++   +K K+ T+   +ALL
Sbjct  597  GRTVIGICPRCGKNVVEGKKSFFCEGWNAAPACDFALWKNDRFFTSKHKELTRKAAAALL  656

Query  657  NDGCVRVTGLYSEKTGKTYDAAVVLEDDGQ-YANFKLEFDQ  696
            + G V +TGL+SEK G  YDA VV+ED G+ +  FKLEFD+
Sbjct  657  KKGRVAMTGLFSEKKGVLYDAIVVMEDTGEKFVRFKLEFDN  697

10) RHOM_01890 in NC_015977


> NC_004668_R1|30|G30|29376814|NP_815968.1|Enterococcus_faecalis_V583|-|30310..32427|topB-2|EF2312|DNA 
topoisomerase III
Length=705

 Score =  649 bits (2455),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 389/701 (56%), Positives = 530/701 (76%), Gaps = 14/701 (1%)

Query  5    KLVIAEKPSVAQSLAAVIGATVRKDGYLEGNGWRVSWCVGHLAGLADADSYDPKYAKWRY  64
            +LVIAEKPSV+ +L+ V+GA  R DGY+EG GW VSWC+GHL  LA AD+YDP+Y+KW Y
Sbjct  2    QLVIAEKPSVGMALSKVLGAKSRGDGYMEGGGWLVSWCIGHLVELAPADAYDPRYSKWNY  61

Query  65   DDLPILPEHWQMVVGkdkkkqfdilkklMNAPDVTEVVNACDAGREGEMIFRSVYELAGC  124
             DLPILP  WQ  V  D KKQF++LK L++ +DVT ++ A DAGREGE+IFR  Y+L GC
Sbjct  62   ADLPILPKPWQFQVLPDTKKQFEVLKTLIHRADVTALICATDAGREGELIFRLTYHLCGC  121

Query  125  KKPMKRLWISSMEDSAIRKGFANLRPGADYDGLRDAALCRAKADWLVGINATRLFSVLYH  184
             KP+KRLWISSME++AI+KGF NL  G +YD L  AALCRAKADWL+GIN+TRLF+ LY+
Sbjct  122  TKPVKRLWISSMEEAAIQKGFDNLLDGKNYDNLYAAALCRAKADWLIGINGTRLFTTLYQ  181

Query  185  -RTLNIGRVMSPTLALIVQREAEIDTFKPIPFYTVALELPGLTVSGERMADKAAAEQLKE  243
             ++LN+GRV +PTLAL+ +REA I  F+   FYTV LEL G+  ++ER A K+ A +L+ 
Sbjct  182  GKSLNVGRVQTPTLALLAEREAAISGFQKEKFYTVELELEGFRAASERFASKTDAGRLRT  241

Query  244  ACQGVNVTIKKVECKEKSEKPPALYDLTTLQRDANRLLGFTAQQTLDYLQSLYEKKLCTY  303
            +C G   T++ V  KEK+E+PP LYDLTTLQR+ANRL+++TAQQTLDYLQ+LYEK+L TY
Sbjct  242  GCVGKPATVQTVSQKEKTERPPKLYDLTTLQREANRLFDYTAQQTLDYLQALYEKRLATY  301

Query  304  PRTDSRYLTGDMADSLPVLVNLVANAMPFRKGIAITCDPQTVINDKKVTDHHAVIPTRNL  363
            PRTDSRYLT DMA +LP L + VA A+PF  ++++  ++  VI++ KVTDHHA++PT + 
Sbjct  302  PRTDSRYLTEDMAAGLPALCQSVAAALPFAADLSLPVNAAQVIDNSKVTDHHAILPTTEA  361

Query  364  KDADLSALPAGEKAVLELVALRLMCAVAQPHIYSETVVIAACAGGEFTTKGKTVKHPGWK  423
              +DLSALP+GEK +L LVA RL+CAV++PH Y+ET V   C+G+ F++KGKT   +GW 
Sbjct  362  AKTDLSALPSGEKNILFLVAARLLCAVGEPHTYAETAVTLECGGAVFSAKGKTETAAGWT  421

Query  424  ALEDAYRAKMKDTEPKKEGVEKALPELTEGQTLSVSAAIVKEGKSSLPQHFTEDTLLSAM  483
            A+E+A++A +K   PK+     +LP LT GQ L+ ++A +KEG +S P HFTEDTLLSAM
Sbjct  422  AMEQAFHATLKKK-PKQPEPSPPLPALTKGQKLTAGGASIKEGATSPPAHFTEDTLLSAM  480

Query  484  ETAGKDDMP--EDAERKGLGTPATRAGILEKLVSAGFLERKKNRKTVQLLPSHDAVSLIT  541
            E A+  + +  ED E+KGLGTPATRAG++EKLV +GF+ERKK+    QL+P++ +  LI 
Sbjct  481  EHASAKEFAKLEDVEHKGLGTPATRAGVIEKLVRSGFVERKKK----QLFPTEKGTELIK  536

Query  542  VLPEQLQSPLLTAEWEYRLGEIERGQLAPEEFLDGISTMLKDLVGTYQVIK-GTEYLFTP  600
            V+P+ L+S  LTAEWE RLG +ERG+L+PE+F+ GI++ML +LV +YQ +  ++  L ++
Sbjct  537  VMPDTLKSVKLTAEWEERLGAVERGELSPEDFMAGITAMLTELVKSYQGVTVASAALSAS  596

Query  601  PREVVGKCPRCGGEVAELQKGFFCQN----DSCKFAIwknnkwwaakkkQPTKAVVSALL  656
             R V+G CPRCG +V E +K+FFC+      +C FA+WKN++  ++K K+ T+   +ALL
Sbjct  597  GRTVIGICPRCGKNVVEGKKSFFCEGWNAAPACDFALWKNDRFFTSKHKELTRKAAAALL  656

Query  657  NDGCVRVTGLYSEKTGKTYDAAVVLEDDGQ-YANFKLEFDQ  696
            + G V +TGL+SEK G  YDA VV+ED G+ +  FKLEFD+
Sbjct  657  KKGRVAMTGLFSEKKGVLYDAIVVMEDTGEKFVRFKLEFDN  697

11) Closa_3709 in NC_014376


> NC_004668_R1|30|G30|29376814|NP_815968.1|Enterococcus_faecalis_V583|-|30310..32427|topB-2|EF2312|DNA 
topoisomerase III
Length=705

 Score =  645 bits (2439),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 373/703 (54%), Positives = 514/703 (74%), Gaps = 17/703 (2%)

Query  1    MKLVLAEKPSVAMSLSKVIGANQRGDGYMEGNGYIVSWCVGHLVELSQPEAYDEKYAKWR  60
            M+LV+AEKPSV+M+LSKV+GA+ RGDGYMEG G +VSWC+GHLVEL+ ++AYD +Y+KW 
Sbjct  1    MQLVIAEKPSVGMALSKVLGAKSRGDGYMEGGGWLVSWCIGHLVELAPADAYDPRYSKWN  60

Query  61   YDDLPILPEHWQYQVSTSTKKQFGILKKLMLRKDVKSLICATDAGREGELIFRLVYHQCG  120
            Y DLPILP  WQ+QV   TKKQF +LK L+ R DV +LICATDAGREGELIFRL YH CG
Sbjct  61   YADLPILPKPWQFQVLPDTKKQFEVLKTLIHRADVTALICATDAGREGELIFRLTYHLCG  120

Query  121  CKKPVERLWISSMEDSAIREGFQKLRPGTEYDALYEAALCRERADWIVGINATRLFSCLY  180
            C KPV RLWISSME++AI+ GF++L  G +YD LY AALCR +ADW++GIN+TRLF+ LY
Sbjct  121  CTKPVKRLWISSMEEAAIQKGFDNLLDGKNYDNLYAAALCRAKADWLIGINGTRLFTTLY  180

Query  181  -GQTLNVGRVMTPTLAMVVMRDAAIRAFKPEPFYSAELKFRDFQAGGERMkekaeaeklv  239
             G++LNVGRV TPTLA++  R+AAI +F+ E FY+ EL + +F+A++ER   K++A +L 
Sbjct  181  QGKSLNVGRVQTPTLALLAEREAAISGFQKEKFYTVELELEGFRAASERFASKTDAGRLR  240

Query  240  aeCCQAGSAIITKVEQKEKSEKPPALFDLTSLQREANRQLGFTAQQTLDYTQALYEKKLV  299
            + C  + +A +  V QKEK+E+PP L+DLT+LQREANR +++TAQQTLDY QALYEK+L 
Sbjct  241  TGCV-GKPATVQTVSQKEKTERPPKLYDLTTLQREANRLFDYTAQQTLDYLQALYEKRLA  299

Query  300  TYPRTDSRYLTDDMAPLVPELVSVIQQSFQIQPDVPAPVNAAQVINSKKVTDHHAIIPTK  359
            TYPRTDSRYLT+DMA+ +P L   +  ++ + +D++ PVNAAQVI++ KVTDHHAI+PT 
Sbjct  300  TYPRTDSRYLTEDMAAGLPALCQSVAAALPFAADLSLPVNAAQVIDNSKVTDHHAILPTT  359

Query  360  TAAGHDISSLPSGEQAILIMLAVRLICAVGTPCRYAETIVEAECAGQKFRTKGKTVTDMG  419
             AA  D+S+LPSGE+ IL+++A RL+CAVG P  YAET V  EC+G  F +KGKT T  G
Sbjct  360  EAAKTDLSALPSGEKNILFLVAARLLCAVGEPHTYAETAVTLECGGAVFSAKGKTETAAG  419

Query  420  W----RQYAGRSSEDAEKNAEACNLPELSEGMTLELAGVDLKEGKTSPPKRFTEDLLLSA  475
            W    + + +     + +   +  LP L+ G  L  +G  +KEG TSPP +FTED LLSA
Sbjct  420  WTAMEQAFHATLKKKPKQPEPSPPLPALTKGQKLTAGGASIKEGATSPPAHFTEDTLLSA  479

Query  476  MESASSDEFP--AGVERKGIGTPATRAAIIEKLVQKGFIERRGDKKTKYLCSTDKGNALV  533
            ME AS+ EF+   +VE+KG+GTPATRA++IEKLV+ GF+ER    K K L +T+KG  L+
Sbjct  480  MEHASAKEFAKLEDVEHKGLGTPATRAGVIEKLVRSGFVER----KKKQLFPTEKGTELI  535

Query  534  TVVPEQIQSPSMTADWEEKLLKIEHGEYDSDAFMGEISSMVNGLVKTYEAVK-GADVLMQ  592
             V+P+ ++S  +TA+WEE+L  +E+GE  ++ FM+ I++M+  LVK+Y++V  ++  L  
Sbjct  536  KVMPDTLKSVKLTAEWEERLGAVERGELSPEDFMAGITAMLTELVKSYQGVTVASAALSA  595

Query  593  PERKVIGSCPACGSDVCETVKGWFCRD----KSCKFALWKENRFFQTLGKQMTEELAKQL  648
            + R VIG CP CG +V E  K+ FC +     +C FALWK++RFF +  K++T   A  L
Sbjct  596  SGRTVIGICPRCGKNVVEGKKSFFCEGWNAAPACDFALWKNDRFFTSKHKELTRKAAAAL  655

Query  649  VNQGKARLTHCYSRKSNRYYDTTVRVETGEDGAAAFKLEFGGK  691
            +++G+  +T  +S K    YD+ V +E   +    FKLEF+ +
Sbjct  656  LKKGRVAMTGLFSEKKGVLYDAIVVMEDTGEKFVRFKLEFDNN  698

12) EUS_14250 in NC_021011


> NC_004668_R1|30|G30|29376814|NP_815968.1|Enterococcus_faecalis_V583|-|30310..32427|topB-2|EF2312|DNA 
topoisomerase III
Length=705

 Score =  644 bits (2434),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 386/701 (56%), Positives = 532/701 (76%), Gaps = 14/701 (1%)

Query  5    KLVIAEKPSVAQSLAAVIGATARKDGYLEGNGWRVSWCVGHLAGLADADSYDPKYAKWRY  64
            +LVIAEKPSV+ +L+ V+GA +R DGY+EG GW VSWC+GHL  LA AD+YDP+Y+KW Y
Sbjct  2    QLVIAEKPSVGMALSKVLGAKSRGDGYMEGGGWLVSWCIGHLVELAPADAYDPRYSKWNY  61

Query  65   DDLPILPEHWQMVVGkdkkkqfdilkklMNAPDVTEVVNACDAGREGEMIFRSVYELADC  124
             DLPILP  WQ  V  D KKQF++LK L++ +DVT ++ A DAGREGE+IFR  Y+L +C
Sbjct  62   ADLPILPKPWQFQVLPDTKKQFEVLKTLIHRADVTALICATDAGREGELIFRLTYHLCGC  121

Query  125  QKPMKRLWISSMEDSAIREGFANLRPGADYDGLRDAALCRAKADWLVGINATRLFSVLYH  184
             KP+KRLWISSME++AI+ GF NL  G +YD L  AALCRAKADWL+GIN+TRLF+ LY+
Sbjct  122  TKPVKRLWISSMEEAAIQKGFDNLLDGKNYDNLYAAALCRAKADWLIGINGTRLFTTLYQ  181

Query  185  -RTLNIGRVMSPTLALIVQREAEIDTFKPVPFYTVALELPGLTVSGERMSDRASAEQMKE  243
             ++LN+GRV +PTLAL+ +REA I  F+   FYTV LEL G+  ++ER + ++ A +++ 
Sbjct  182  GKSLNVGRVQTPTLALLAEREAAISGFQKEKFYTVELELEGFRAASERFASKTDAGRLRT  241

Query  244  ACQDAAVAIKKVECKEKSEKPPALYDLTTLQRDANRLLGFTAQQTLDYLQSLYEKKLCTY  303
            +C + + +++ V  KEK+E+PP LYDLTTLQR+ANRL+++TAQQTLDYLQ+LYEK+L TY
Sbjct  242  GCVGKPATVQTVSQKEKTERPPKLYDLTTLQREANRLFDYTAQQTLDYLQALYEKRLATY  301

Query  304  PRTDSRYLTGDMADSLPVLVNLVANAMPFCKEIAITCDPHTVINDKKVTDHHAVIPTRNL  363
            PRTDSRYLT DMA +LP L + VA A+PF  ++++  ++  VI++ KVTDHHA++PT + 
Sbjct  302  PRTDSRYLTEDMAAGLPALCQSVAAALPFAADLSLPVNAAQVIDNSKVTDHHAILPTTEA  361

Query  364  KDADLSALPAGEKAVLELVALRLLCAVAQPHIYSETVVIAACADGEFTAKGKTVKHPGWK  423
              +DLSALP+GEK +L LVA RLLCAV++PH Y+ET V   C+++ F+AKGKT   +GW 
Sbjct  362  AKTDLSALPSGEKNILFLVAARLLCAVGEPHTYAETAVTLECGGAVFSAKGKTETAAGWT  421

Query  424  ALEDACRAKMKDAEPKKEGAEKALPELTEGQTLSVSAAIVKEGKSSPPQHFTEDTLLSAM  483
            A+E+A +A +K   PK+  +  +LP LT GQ L+ ++A +KEG +SPP HFTEDTLLSAM
Sbjct  422  AMEQAFHATLKK-KPKQPEPSPPLPALTKGQKLTAGGASIKEGATSPPAHFTEDTLLSAM  480

Query  484  ETAGKEDMP--EDAERKGLGTPATRAGILEKLVSAGFLERKKSRKTVQLLPSHDAVSLIT  541
            E A+  + +  ED E+KGLGTPATRAG++EKLV +GF+ERKK     QL+P++ +  LI 
Sbjct  481  EHASAKEFAKLEDVEHKGLGTPATRAGVIEKLVRSGFVERKKK----QLFPTEKGTELIK  536

Query  542  VLPEQLQSPLLTAEWEYRLGEIEHGQLAPEEFLAGISTMLKDLVGTYQVIK-GTEYLFTP  600
            V+P+ L+S  LTAEWE RLG +E+G+L+PE+F+AGI++ML +LV +YQ +  ++  L ++
Sbjct  537  VMPDTLKSVKLTAEWEERLGAVERGELSPEDFMAGITAMLTELVKSYQGVTVASAALSAS  596

Query  601  PREVVGKCPRCGGEVAELQKGFFCQ----SKECRFAIwknnkwwtakkkQPTKAVVSALL  656
             R V+G CPRCG +V E +K+FFC+    +  C FA+WKN++  T+K K+ T+   +ALL
Sbjct  597  GRTVIGICPRCGKNVVEGKKSFFCEGWNAAPACDFALWKNDRFFTSKHKELTRKAAAALL  656

Query  657  KDGCVRVTGLYSEKTGKTYDATVVLEDDGQ-YANFKLEFDQ  696
            K G V +TGL+SEK G  YDA VV+ED G+ +  FKLEFD+
Sbjct  657  KKGRVAMTGLFSEKKGVLYDAIVVMEDTGEKFVRFKLEFDN  697

13) FPR_14240 in NC_021020


> NC_004668_R1|30|G30|29376814|NP_815968.1|Enterococcus_faecalis_V583|-|30310..32427|topB-2|EF2312|DNA 
topoisomerase III
Length=705

 Score =  644 bits (2433),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 386/701 (56%), Positives = 532/701 (76%), Gaps = 14/701 (1%)

Query  4    KLVIAEKPSVAQSLAAVIGATARKDGYLEGNGWRVSWCVGHLAGLADADSYDPKYAKWRY  63
            +LVIAEKPSV+ +L+ V+GA +R DGY+EG GW VSWC+GHL  LA AD+YDP+Y+KW Y
Sbjct  2    QLVIAEKPSVGMALSKVLGAKSRGDGYMEGGGWLVSWCIGHLVELAPADAYDPRYSKWNY  61

Query  64   DDLPILPEHWQMVVGkdkkkqfdilkklMNAPDVTEVVNACDAGREGEMIFRSVYELADC  123
             DLPILP  WQ  V  D KKQF++LK L++ +DVT ++ A DAGREGE+IFR  Y+L +C
Sbjct  62   ADLPILPKPWQFQVLPDTKKQFEVLKTLIHRADVTALICATDAGREGELIFRLTYHLCGC  121

Query  124  QKPMKRLWISSMEDSAIREGFANLRPGADYDGLRDAALCRAKADWLVGINATRLFSVLYH  183
             KP+KRLWISSME++AI+ GF NL  G +YD L  AALCRAKADWL+GIN+TRLF+ LY+
Sbjct  122  TKPVKRLWISSMEEAAIQKGFDNLLDGKNYDNLYAAALCRAKADWLIGINGTRLFTTLYQ  181

Query  184  -RTLNIGRVMSPTLALIVQREAEIDTFKPVPFYTVALELPGLTVSGERMSDRASAEQMKE  242
             ++LN+GRV +PTLAL+ +REA I  F+   FYTV LEL G+  ++ER + ++ A +++ 
Sbjct  182  GKSLNVGRVQTPTLALLAEREAAISGFQKEKFYTVELELEGFRAASERFASKTDAGRLRT  241

Query  243  ACQDAAVAIKKVECKEKSEKPPALYDLTTLQRDANRLLGFTAQQTLDYLQSLYEKKLCTY  302
            +C + + +++ V  KEK+E+PP LYDLTTLQR+ANRL+++TAQQTLDYLQ+LYEK+L TY
Sbjct  242  GCVGKPATVQTVSQKEKTERPPKLYDLTTLQREANRLFDYTAQQTLDYLQALYEKRLATY  301

Query  303  PRTDSRYLTGDMADSLPVLVNLVANAMPFCKEIAITCDPHTVINDKKVTDHHAVIPTRNL  362
            PRTDSRYLT DMA +LP L + VA A+PF  ++++  ++  VI++ KVTDHHA++PT + 
Sbjct  302  PRTDSRYLTEDMAAGLPALCQSVAAALPFAADLSLPVNAAQVIDNSKVTDHHAILPTTEA  361

Query  363  KDADLSALPAGEKAVLELVALRLLCAVAQPHIYSETVVIAACADGEFTAKGKTVKHPGWK  422
              +DLSALP+GEK +L LVA RLLCAV++PH Y+ET V   C+++ F+AKGKT   +GW 
Sbjct  362  AKTDLSALPSGEKNILFLVAARLLCAVGEPHTYAETAVTLECGGAVFSAKGKTETAAGWT  421

Query  423  ALEDACRAKMKDAEPKKEGAEKALPELTEGQTLSVSAAIVKEGKSSPPQHFTEDTLLSAM  482
            A+E+A +A +K   PK+  +  +LP LT GQ L+ ++A +KEG +SPP HFTEDTLLSAM
Sbjct  422  AMEQAFHATLKK-KPKQPEPSPPLPALTKGQKLTAGGASIKEGATSPPAHFTEDTLLSAM  480

Query  483  ETAGKEDMP--EDAERKGLGTPATRAGILEKLVSAGFLERKKSRKTVQLLPSHDAVSLIT  540
            E A+  + +  ED E+KGLGTPATRAG++EKLV +GF+ERKK     QL+P++ +  LI 
Sbjct  481  EHASAKEFAKLEDVEHKGLGTPATRAGVIEKLVRSGFVERKKK----QLFPTEKGTELIK  536

Query  541  VLPEQLQSPLLTAEWEYRLGEIEHGQLAPEEFLAGISTMLKDLVGTYQVIK-GTEYLFTP  599
            V+P+ L+S  LTAEWE RLG +E+G+L+PE+F+AGI++ML +LV +YQ +  ++  L ++
Sbjct  537  VMPDTLKSVKLTAEWEERLGAVERGELSPEDFMAGITAMLTELVKSYQGVTVASAALSAS  596

Query  600  PREVVGKCPRCGGEVAELQKGFFCQ----SKECRFAIwknnkwwtakkkQPTKAVVSALL  655
             R V+G CPRCG +V E +K+FFC+    +  C FA+WKN++  T+K K+ T+   +ALL
Sbjct  597  GRTVIGICPRCGKNVVEGKKSFFCEGWNAAPACDFALWKNDRFFTSKHKELTRKAAAALL  656

Query  656  KDGCVRVTGLYSEKTGKTYDATVVLEDDGQ-YANFKLEFDQ  695
            K G V +TGL+SEK G  YDA VV+ED G+ +  FKLEFD+
Sbjct  657  KKGRVAMTGLFSEKKGVLYDAIVVMEDTGEKFVRFKLEFDN  697

14) topB in NC_009089


> NC_004668_R1|30|G30|29376814|NP_815968.1|Enterococcus_faecalis_V583|-|30310..32427|topB-2|EF2312|DNA 
topoisomerase III
Length=705

 Score =  641 bits (2421),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 359/702 (52%), Positives = 507/702 (73%), Gaps = 11/702 (1%)

Query  1    MILVIAEKPSVAQTIAAVLGVKEKKDGFLTGSGYIVSWCVGHLVGLAEAAAYGEQYKKWN  60
            M LVIAEKPSV+ +++ VLG K + DG++ G+G +VSWC+GHLV LA A AY+ +Y KWN
Sbjct  1    MQLVIAEKPSVGMALSKVLGAKSRGDGYMEGGGWLVSWCIGHLVELAPADAYDPRYSKWN  60

Query  61   YDSLPILPQEWKYTVAADKEKQFKTLKELMHRADVSEVVNACDAGREGELIFRFVYEMAG  120
            Y  LPILP+ W++ V +D  KQF  LK L+HRADV+ ++ A DAGREGELIFR+ Y++ G
Sbjct  61   YADLPILPKPWQFQVLPDTKKQFEVLKTLIHRADVTALICATDAGREGELIFRLTYHLCG  120

Query  121  CKKPMRRLWISSMEDSAIKEGFSRLKNGKEYDALFASALCRAKADWLIGINATRLFSVLY  180
            C KP++RLWISSME++AI+ GF  L +GK+YD L+A+ALCRAKADWLIGIN+TRLF+ LY
Sbjct  121  CTKPVKRLWISSMEEAAIQKGFDNLLDGKNYDNLYAAALCRAKADWLIGINGTRLFTTLY  180

Query  181  N-HTLNVGRVQTPTLKMLVDRDAAITTFKKEKYYHVRLALSGAEAASERISNKAEADTLK  239
            +  +LNVGRVQTPTL +L +R+AAI+ F+KEK+Y V L L G  AASER+++K++A+ L+
Sbjct  181  QGKSLNVGRVQTPTLALLAEREAAISGFQKEKFYTVELELEGFRAASERFASKTDAGRLR  240

Query  240  TTCEASKAVCTSLLKEKKTAAPPKLFDLTSLQREANCLFGYTAKQTLDLAQALYEKRLLT  299
            T C +  A   ++ +  KT  PPKL+DLT+LQREAN LF+YTA+QTLD  QALYEKRL T
Sbjct  241  TGCVGKPATVQTVSQKEKTERPPKLYDLTTLQREANRLFDYTAQQTLDYLQALYEKRLAT  300

Query  300  YPRTDSSYLTDDMGDTAAGIIKLLCGKFPFMAGKDFTPELAKVLNSKKVSDHHAIIPTME  359
            YPRTDS YLT+DM+   +++ + + + +PF A+  +  + A+V+++ KV+DHHAI+PT E
Sbjct  301  YPRTDSRYLTEDMAAGLPALCQSVAAALPFAADLSLPVNAAQVIDNSKVTDHHAILPTTE  360

Query  360  LAKTDLAALPESERNILTIAGARLIMATAAPHTFEAVTAVFECAGQSFTARGKTVLSDGW  419
             AKTDL+ALP +E+NIL + +ARL+ A + PHT+   +  +EC+G  F+A+GKT  + GW
Sbjct  361  AAKTDLSALPSGEKNILFLVAARLLCAVGEPHTYAETAVTLECGGAVFSAKGKTETAAGW  420

Query  420  KEIDRKYRAILKSKPETDDADSDTEKTLPPFTEGQNFDNPAAKVTEHDTTPPKPHNEASL  479
              +++ ++A LK KP     +++    LP++T GQ++   +A + E  T+PP    E +L
Sbjct  421  TAMEQAFHATLKKKPK----QPEPSPPLPALTKGQKLTAGGASIKEGATSPPAHFTEDTL  476

Query  480  LSAMERAGSEDTD--PDAERKGLGTPATRAAVIEKLVKGGFVERKGKQLLPTKDGINLVC  537
            LSAME+A++ +     D E+KGLGTPATRA+VIEKLV++GFVERK KQL+PT  G +L+ 
Sbjct  477  LSAMEHASAKEFAKLEDVEHKGLGTPATRAGVIEKLVRSGFVERKKKQLFPTEKGTELIK  536

Query  538  VLPDTLTSPQLTAEWENNLTQIAKGKADPAAFMKGIEDMARELVKTYPFLSEADKGRFKE  597
            V+PDTL S +LTAEWE+ L  + +G   P  FM GI  M  ELVK+Y  ++ A  +    
Sbjct  537  VMPDTLKSVKLTAEWEERLGAVERGELSPEDFMAGITAMLTELVKSYQGVTVASAALSAS  596

Query  598  EKPELGKCPRCGSPVYEGKKNYYC----SNKECSFTMWKNDRFFEERKVTFTPKIAAALL  653
             +  +G CPRCG  V EGKK+++C    +   C F++WKNDRFF  +   +T K AAALL
Sbjct  597  GRTVIGICPRCGKNVVEGKKSFFCEGWNAAPACDFALWKNDRFFTSKHKELTRKAAAALL  656

Query  654  KSGKVNVKKLYSPKTGKTYDGTIALADTGEKYVNYRIELSKK  695
            K G+V +  L+S K G  YD+ + + DTGEK+V +++E+ ++
Sbjct  657  KKGRVAMTGLFSEKKGVLYDAIVVMEDTGEKFVRFKLEFDNN  698

15) ES1_15040 in NC_021043


> NC_004668_R1|30|G30|29376814|NP_815968.1|Enterococcus_faecalis_V583|-|30310..32427|topB-2|EF2312|DNA 
topoisomerase III
Length=705

 Score =  631 bits (2385),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 367/694 (53%), Positives = 504/694 (73%), Gaps = 7/694 (1%)

Query  1    MKLVIAEKPSVGAAIAAVMGANEKRSGYFEGGGYLVSWCIGHLISLADAATYNEQFRKWK  60
            M+LVIAEKPSVG A++ V+GA+ +  GY EGGG LVSWCIGHL+ LA A +Y+ ++ KW+
Sbjct  1    MQLVIAEKPSVGMALSKVLGAKSRGDGYMEGGGWLVSWCIGHLVELAPADAYDPRYSKWN  60

Query  61   YDDLPIVPQEWQFIVASGKEQQFSILKDLMHRSDVTEIINACDSGREGELIFRFVYEQAN  120
            Y DLPI+P+ WQF V ++  +QF +LK L+HR+DVT +I A D+GREGELIFR+ Y+   
Sbjct  61   YADLPILPKPWQFQVLPDTKKQFEVLKTLIHRADVTALICATDAGREGELIFRLTYHLCG  120

Query  121  CKKPFSRLWISSMEASAIREGFSNLKDGRGYDNLYQSALCRAKADWLIGINATRLFSILY  180
            C KP  RLWISSME +AI+ GF NL DG+ YDNLY +ALCRAKADWLIGIN+TRLF+ LY
Sbjct  121  CTKPVKRLWISSMEEAAIQKGFDNLLDGKNYDNLYAAALCRAKADWLIGINGTRLFTTLY  180

Query  181  H-KTLNVGRVQTPTLAMLVNRDYAISSFKKEKYHVVRLDVGGVAALSERQDDEAAARQMK  239
            + K+LNVGRVQTPTLA+L +R+ AIS+F+KEK+  V L++ G  A SER    + A +++
Sbjct  181  QGKSLNVGRVQTPTLALLAEREAAISGFQKEKFYTVELELEGFRAASERFASKTDAGRLR  240

Query  240  AACEKSQAVCTSLKKEKKTAAPPKLFDLTALQREANRLYGFTAKQTLDYAQALYEKRLLT  299
            ++C    A   ++ +  KT  PPKL+DLT+LQREANRL+++TA+QTLDY QALYEKRL T
Sbjct  241  TGCVGKPATVQTVSQKEKTERPPKLYDLTTLQREANRLFDYTAQQTLDYLQALYEKRLAT  300

Query  300  YPRTDSKYITSDMEGSTKELITGLCAALPFMQGVKLQADLARICDNSKVTDHHAILPTAE  359
            YPRTDS+Y+T DM ++   L  ++ AALPF  ++ L  + A++ DNSKVTDHHAILPT+E
Sbjct  301  YPRTDSRYLTEDMAAGLPALCQSVAAALPFAADLSLPVNAAQVIDNSKVTDHHAILPTTE  360

Query  360  FVKTGFSSLAESEKKLMTlvcakllcavaaPYEYEAVTAVFTCGGYTFTAKGRTTLCEGW  419
              KT++S+L+ +EK+++ LV A+LLCAV+ P  Y   +  + CGG  F+AKG+T    GW
Sbjct  361  AAKTDLSALPSGEKNILFLVAARLLCAVGEPHTYAETAVTLECGGAVFSAKGKTETAAGW  420

Query  420  REIERLSRAASGEQDEDAEPEAVLPPLAEGQTFDNPAAEISERYTQPPKAFTEDTLLSAM  479
              +E+  +A+   +  ++EP + LP+L+ GQ +   +A I E  T PP  FTEDTLLSAM
Sbjct  421  TAMEQAFHATLKKKPKQPEPSPPLPALTKGQKLTAGGASIKEGATSPPAHFTEDTLLSAM  480

Query  480  ESAGKED--TPEDAERKGLGTTATRAGIIEKLISAGFAERKGKKLIPTKDGYNLVAILPD  537
            E A+  +    ED E+KGLGT ATRAG+IEKL+ +GF ERK K+L+PT  G +L+ ++PD
Sbjct  481  EHASAKEFAKLEDVEHKGLGTPATRAGVIEKLVRSGFVERKKKQLFPTEKGTELIKVMPD  540

Query  538  SLTSPQLTAEWETRLTGIAKGSDSPADFMRGIEEMTAGLVKTYSAISEDKAKLFTPQREA  597
            +L S +LTAEWE RL ++ +G  SP DFM GI  M + LVK+Y +++   A L ++ R  
Sbjct  541  TLKSVKLTAEWEERLGAVERGELSPEDFMAGITAMLTELVKSYQGVTVASAALSASGRTV  600

Query  598  IGTCPRCGAAVYEGKKNFYCSDR----ACSFVMWKNDRFFEQRKKAFTKAIAAALLKDGK  653
            IG CPRCG  V EGKK+F+C ++    AC F +WKNDRFF  + K +T+  AAALLK G+
Sbjct  601  IGICPRCGKNVVEGKKSFFCEGWNAAPACDFALWKNDRFFTSKHKELTRKAAAALLKKGR  660

Query  654  VKIKGMYSTKTGKTFDGVVLLADTGGKYVNFRVE  687
            V + G++S K G  +D++V++ DTG K+V F++E
Sbjct  661  VAMTGLFSEKKGVLYDAIVVMEDTGEKFVRFKLE  694

16) RBR_01000 in NC_021013


> NC_004668_R1|30|G30|29376814|NP_815968.1|Enterococcus_faecalis_V583|-|30310..32427|topB-2|EF2312|DNA 
topoisomerase III
Length=705

 Score =  631 bits (2385),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 367/694 (53%), Positives = 504/694 (73%), Gaps = 7/694 (1%)

Query  1    MKLVIAEKPSVGAAIAAVMGANEKRSGYFEGGGYLVSWCIGHLISLADAATYNEQFRKWK  60
            M+LVIAEKPSVG A++ V+GA+ +  GY EGGG LVSWCIGHL+ LA A +Y+ ++ KW+
Sbjct  1    MQLVIAEKPSVGMALSKVLGAKSRGDGYMEGGGWLVSWCIGHLVELAPADAYDPRYSKWN  60

Query  61   YDDLPIVPQEWQFIVASGKEQQFSILKDLMHRSDVTEIINACDSGREGELIFRFVYEQAN  120
            Y DLPI+P+ WQF V ++  +QF +LK L+HR+DVT +I A D+GREGELIFR+ Y+   
Sbjct  61   YADLPILPKPWQFQVLPDTKKQFEVLKTLIHRADVTALICATDAGREGELIFRLTYHLCG  120

Query  121  CKKPFSRLWISSMEASAIREGFSNLKDGRGYDNLYQSALCRAKADWLIGINATRLFSILY  180
            C KP  RLWISSME +AI+ GF NL DG+ YDNLY +ALCRAKADWLIGIN+TRLF+ LY
Sbjct  121  CTKPVKRLWISSMEEAAIQKGFDNLLDGKNYDNLYAAALCRAKADWLIGINGTRLFTTLY  180

Query  181  H-KTLNVGRVQTPTLAMLVNRDYAISSFKKEKYHVVRLDVGGVAALSERQDDEAAARQMK  239
            + K+LNVGRVQTPTLA+L +R+ AIS+F+KEK+  V L++ G  A SER    + A +++
Sbjct  181  QGKSLNVGRVQTPTLALLAEREAAISGFQKEKFYTVELELEGFRAASERFASKTDAGRLR  240

Query  240  AACEKSQAVCTSLKKEKKTAAPPKLFDLTALQREANRLYGFTAKQTLDYAQALYEKRLLT  299
            ++C    A   ++ +  KT  PPKL+DLT+LQREANRL+++TA+QTLDY QALYEKRL T
Sbjct  241  TGCVGKPATVQTVSQKEKTERPPKLYDLTTLQREANRLFDYTAQQTLDYLQALYEKRLAT  300

Query  300  YPRTDSKYITSDMEGSTKELITGLCAALPFMQGVKLQADLARICDNSKVTDHHAILPTAE  359
            YPRTDS+Y+T DM ++   L  ++ AALPF  ++ L  + A++ DNSKVTDHHAILPT+E
Sbjct  301  YPRTDSRYLTEDMAAGLPALCQSVAAALPFAADLSLPVNAAQVIDNSKVTDHHAILPTTE  360

Query  360  FVKTGFSSLAESEKKLMTlvcakllcavaaPYEYEAVTAVFTCGGYTFTAKGRTTLCEGW  419
              KT++S+L+ +EK+++ LV A+LLCAV+ P  Y   +  + CGG  F+AKG+T    GW
Sbjct  361  AAKTDLSALPSGEKNILFLVAARLLCAVGEPHTYAETAVTLECGGAVFSAKGKTETAAGW  420

Query  420  REIERLSRAASGEQDEDAEPEAVLPPLAEGQTFDNPAAEISERYTQPPKAFTEDTLLSAM  479
              +E+  +A+   +  ++EP + LP+L+ GQ +   +A I E  T PP  FTEDTLLSAM
Sbjct  421  TAMEQAFHATLKKKPKQPEPSPPLPALTKGQKLTAGGASIKEGATSPPAHFTEDTLLSAM  480

Query  480  ESAGKED--TPEDAERKGLGTTATRAGIIEKLISAGFAERKGKKLIPTKDGYNLVAILPD  537
            E A+  +    ED E+KGLGT ATRAG+IEKL+ +GF ERK K+L+PT  G +L+ ++PD
Sbjct  481  EHASAKEFAKLEDVEHKGLGTPATRAGVIEKLVRSGFVERKKKQLFPTEKGTELIKVMPD  540

Query  538  SLTSPQLTAEWETRLTGIAKGSDSPADFMRGIEEMTAGLVKTYSAISEDKAKLFTPQREA  597
            +L S +LTAEWE RL ++ +G  SP DFM GI  M + LVK+Y +++   A L ++ R  
Sbjct  541  TLKSVKLTAEWEERLGAVERGELSPEDFMAGITAMLTELVKSYQGVTVASAALSASGRTV  600

Query  598  IGTCPRCGAAVYEGKKNFYCSDR----ACSFVMWKNDRFFEQRKKAFTKAIAAALLKDGK  653
            IG CPRCG  V EGKK+F+C ++    AC F +WKNDRFF  + K +T+  AAALLK G+
Sbjct  601  IGICPRCGKNVVEGKKSFFCEGWNAAPACDFALWKNDRFFTSKHKELTRKAAAALLKKGR  660

Query  654  VKIKGMYSTKTGKTFDGVVLLADTGGKYVNFRVE  687
            V + G++S K G  +D++V++ DTG K+V F++E
Sbjct  661  VAMTGLFSEKKGVLYDAIVVMEDTGEKFVRFKLE  694

17) CK5_22580 in NC_021022


> NC_004668_R1|30|G30|29376814|NP_815968.1|Enterococcus_faecalis_V583|-|30310..32427|topB-2|EF2312|DNA 
topoisomerase III
Length=705

 Score =  630 bits (2382),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 359/701 (52%), Positives = 500/701 (72%), Gaps = 10/701 (1%)

Query  1    MKLVICEKPSvgaavaaalgvREKKDGYIEGNGYVISWCIGHLVGLAEAAAYGEQYRKWS  60
            M+LVI EKPSVG A++  LG + + DGY+EG G ++SWCIGHLV LA A AY+ +Y KW+
Sbjct  1    MQLVIAEKPSVGMALSKVLGAKSRGDGYMEGGGWLVSWCIGHLVELAPADAYDPRYSKWN  60

Query  61   YDSLPILPQEWQYTVAADKGKQFKILKDLMQRSDVSEVVNACDAGREGELIFRFVYHQAG  120
            Y  LPILP+ WQ+ V +D  KQF +LK L++R+DV+ ++ A DAGREGELIFR+ YH  G
Sbjct  61   YADLPILPKPWQFQVLPDTKKQFEVLKTLIHRADVTALICATDAGREGELIFRLTYHLCG  120

Query  121  CKKPFTRLWISSMETDAIKSGFDNLKDGRRYDALYHSALCRAKADWLIGINATRLFSCLY  180
            C KP  RLWISSME  AI+ GFDNL DG+ YD LY +ALCRAKADWLIGIN+TRLF+ LY
Sbjct  121  CTKPVKRLWISSMEEAAIQKGFDNLLDGKNYDNLYAAALCRAKADWLIGINGTRLFTTLY  180

Query  181  -GKTLNVGRVQTPTLKMLVDRDAAIMNFKKEKYYHVRLMLPGAEAASAKICAADEAGKLK  239
             GK+LNVGRVQTPTL +L +R+AAI  F+KEK+Y V L L G  AAS ++ +  +AG+L+
Sbjct  181  QGKSLNVGRVQTPTLALLAEREAAISGFQKEKFYTVELELEGFRAASERFASKTDAGRLR  240

Query  240  AACEASAAVCTSLTRENKTAIPPKLFDLTSLQREANRIYGYTAKQTFDLAQTLYEKKLLT  299
            ++C + +A   ++++ +KT  PPKL+DLT+LQREANR+++YTA+QT+D  Q+LYEK+L T
Sbjct  241  TGCVGKPATVQTVSQKEKTERPPKLYDLTTLQREANRLFDYTAQQTLDYLQALYEKRLAT  300

Query  300  YPRTDSNYLTDDMGDTAASIVSLLCGKLPFMASAAYEQSISRVLNSKKVSDHHAIIPTME  359
            YPRTDS YLT+DM+   +++   + + LPF A  +   + ++V+++ KV+DHHAI+PT E
Sbjct  301  YPRTDSRYLTEDMAAGLPALCQSVAAALPFAADLSLPVNAAQVIDNSKVTDHHAILPTTE  360

Query  360  IAKTDLTTLPESERNILILTGARLLMATAEPHVYEAVTAVFSCADHEFTARGKTVIAAGW  419
             AKTDL++LP +E+NIL+L +ARLL A +EPH Y   +  + C++  F+A+GKT  AAGW
Sbjct  361  AAKTDLSALPSGEKNILFLVAARLLCAVGEPHTYAETAVTLECGGAVFSAKGKTETAAGW  420

Query  420  KNIERLYRATLKKKPDSDDENELVLDVPDFTEGQTFENPAAKVTEHETTPPKPHNEASLL  479
              +E+ ++ATLKKKP   + +     +P +T GQ +   +A + E  T+PP    E +LL
Sbjct  421  TAMEQAFHATLKKKPKQPEPSP---PLPALTKGQKLTAGGASIKEGATSPPAHFTEDTLL  477

Query  480  SAMERAGNEDTD--PDAERRGLGTPATRAAVIEKLVKGGFVERKGKQLLPTKDGTSLVCV  537
            SAME+A+  +     D E++GLGTPATRA+VIEKLV++GFVERK KQL+PT  GT L+ V
Sbjct  478  SAMEHASAKEFAKLEDVEHKGLGTPATRAGVIEKLVRSGFVERKKKQLFPTEKGTELIKV  537

Query  538  LPDSLTSPQLTAAWENNLTQIAKGNADPAAFMQGIEAMAQELVKTYASVLGEKQELFKTE  597
            +PD+L S +LTA WE+ L  + +G+  P  FM GI AM  ELVK+Y +V      L  + 
Sbjct  538  MPDTLKSVKLTAEWEERLGAVERGELSPEDFMAGITAMLTELVKSYQGVTVASAALSASG  597

Query  598  KTELGKCPRCKSPVYEGKKNYYC----SNKECSFTMWKNDRFFEERKTVFTPKIAAALLK  653
            +T +G CPRC   V EGKK+++C    +   C F++WKNDRFF  +   +T K AAALLK
Sbjct  598  RTVIGICPRCGKNVVEGKKSFFCEGWNAAPACDFALWKNDRFFTSKHKELTRKAAAALLK  657

Query  654  SGKAKVKKLYSVKTGKTYDGTVLLADTGGKYVNYKVTISKD  694
             G+  +  L+S K G  YD+ V++ DTG K+V +K+ + ++
Sbjct  658  KGRVAMTGLFSEKKGVLYDAIVVMEDTGEKFVRFKLEFDNN  698

18) CLS_29900 in NC_021047


> NC_004668_R1|30|G30|29376814|NP_815968.1|Enterococcus_faecalis_V583|-|30310..32427|topB-2|EF2312|DNA 
topoisomerase III
Length=705

 Score =  625 bits (2363),  Expect = 3e-180, Method: Compositional matrix adjust.
 Identities = 357/694 (52%), Positives = 501/694 (73%), Gaps = 7/694 (1%)

Query  1    MKLVIAEKPSVGAAIAAVLGANEKRSGYFEGSGYLVSWCIGHLISLADAATYNEQYRKWK  60
            M+LVIAEKPSVG A++ VLGA+ +  GY EG+G LVSWCIGHL+ LA A +Y+ +Y KW+
Sbjct  1    MQLVIAEKPSVGMALSKVLGAKSRGDGYMEGGGWLVSWCIGHLVELAPADAYDPRYSKWN  60

Query  61   YDDLPIVPQDWQFTVASGKEQQFSVLKDLMHRSDVSEIVNACDSGREGELIFRFVYEQAN  120
            Y DLPI+P+ WQF V ++  +QF VLK L+HR+DV+ ++ A D+GREGELIFR+ Y+   
Sbjct  61   YADLPILPKPWQFQVLPDTKKQFEVLKTLIHRADVTALICATDAGREGELIFRLTYHLCG  120

Query  121  CKKPFSRLWISSMEESAIREGFSNLKDGRSYDDLYQSALCRAKADWLVGINATRLFSILY  180
            C KP  RLWISSMEE+AI+ GF NL DG++YD+LY +ALCRAKADWL+GIN+TRLF+ LY
Sbjct  121  CTKPVKRLWISSMEEAAIQKGFDNLLDGKNYDNLYAAALCRAKADWLIGINGTRLFTTLY  180

Query  181  H-KTLNVGRVQTPTLTMLVNRDYAISSFKKEKYHVVRLNAGGVSALSERLNDEAAAQQMK  239
            + K+LNVGRVQTPTL++L +R+ AIS+F+KEK+  V L+  G  A SER+   + A +++
Sbjct  181  QGKSLNVGRVQTPTLALLAEREAAISGFQKEKFYTVELELEGFRAASERFASKTDAGRLR  240

Query  240  AACEKSQAVCTSLKKEKKTVSPPKLFDLTALQREANRLYGFTAKQTLDYAQALYEKRLLT  299
            ++C    A   ++ +  KT  PPKL+DLT+LQREANRL+++TA+QTLDY QALYEKRL T
Sbjct  241  TGCVGKPATVQTVSQKEKTERPPKLYDLTTLQREANRLFDYTAQQTLDYLQALYEKRLAT  300

Query  300  YPRTDSKYITSDMQDSTKELITGLCSLLPFMRDVKLQADLTRVCDNSKVTDHHAILPTAE  359
            YPRTDS+Y+T DM  +   L  ++ + LPF  D+ L  + ++V DNSKVTDHHAILPT+E
Sbjct  301  YPRTDSRYLTEDMAAGLPALCQSVAAALPFAADLSLPVNAAQVIDNSKVTDHHAILPTTE  360

Query  360  FLKAGFSSLADSETKLMTLVcakllcaaaaPYEYEAVTAAISCGGYTFTAKGKTTLCEGW  419
              K+++S+L+ +E +++ LV A+LLCA + P  Y   + ++ CGG  F+AKGKT    GW
Sbjct  361  AAKTDLSALPSGEKNILFLVAARLLCAVGEPHTYAETAVTLECGGAVFSAKGKTETAAGW  420

Query  420  CEIEKLSRAASEEQDEDAEPETVLPPLAEGQTFDNPAAEISERYTQPPKAYTEDTLLSAM  479
              +E+  +A+   +  ++EP   LP+L+ GQ +   +A I E  T PP  +TEDTLLSAM
Sbjct  421  TAMEQAFHATLKKKPKQPEPSPPLPALTKGQKLTAGGASIKEGATSPPAHFTEDTLLSAM  480

Query  480  ENAGKEETP--EDAERKGLGTTATRAGIIEKLISAGFAERKGKKLIPTKDGYNLAAILPE  537
            E+A+  E +  ED E+KGLGT ATRAG+IEKL+ +GF ERK K+L+PT  G +L  ++P+
Sbjct  481  EHASAKEFAKLEDVEHKGLGTPATRAGVIEKLVRSGFVERKKKQLFPTEKGTELIKVMPD  540

Query  538  VLTSPQLTAEWETRLTGIAKGSDSPDDFMRSIEEMTAGLVKTYSAISEDKAKLFTPQREA  597
             L S +LTAEWE RL ++ +G  SP+DFM +I  M + LVK+Y +++   A L ++ R  
Sbjct  541  TLKSVKLTAEWEERLGAVERGELSPEDFMAGITAMLTELVKSYQGVTVASAALSASGRTV  600

Query  598  IGTCPRCGAAVYEGKKNYYCSDR----ACSFVMWKNDLFFQQRKKTFTKAIAAALLKDRK  653
            IG CPRCG  V EGKK+++C ++    AC F +WKND FF  + K +T+  AAALLK  +
Sbjct  601  IGICPRCGKNVVEGKKSFFCEGWNAAPACDFALWKNDRFFTSKHKELTRKAAAALLKKGR  660

Query  654  VKIKGMYSTKTGKTFDGVVLLADTGGKYVNFRVE  687
            V + G++S K G  +D++V++ DTG K+V F++E
Sbjct  661  VAMTGLFSEKKGVLYDAIVVMEDTGEKFVRFKLE  694

19) EFAU004_02790 in NC_017022


> NC_004668_R1|30|G30|29376814|NP_815968.1|Enterococcus_faecalis_V583|-|30310..32427|topB-2|EF2312|DNA 
topoisomerase III
Length=705

 Score =  604 bits (2282),  Expect = 6e-174, Method: Compositional matrix adjust.
 Identities = 360/694 (52%), Positives = 515/694 (75%), Gaps = 8/694 (1%)

Query  4    KLVIAEKPSVARSIAGVIGATEKHDGYLEGNGYLVSWCIGHLVSFADAGRYDERFKKWRY  63
            +LVIAEKPSV+ +++ V+GA  + DGY+EG G LVSWCIGHLV +A A+ YD R+ KW Y
Sbjct  2    QLVIAEKPSVGMALSKVLGAKSRGDGYMEGGGWLVSWCIGHLVELAPADAYDPRYSKWNY  61

Query  64   EDLPILPETWQYIVPDDKKQQFDVLCSLMQRPDVTGLVCATDAGREGELIFRFVYQMAGC  123
             DLPILP  WQ+ V  D K+QF+VL +L++R+DVT+L+CATDAGREGELIFR+ Y++ GC
Sbjct  62   ADLPILPKPWQFQVLPDTKKQFEVLKTLIHRADVTALICATDAGREGELIFRLTYHLCGC  121

Query  124  QKPFERLWISSMEDSAIKDGFAHLKPGGDYDPLYQSALCRAKADWLIGINATRLFSVLYH  183
             KP  RLWISSME++AI+ GF +L  G +YD LY +ALCRAKADWLIGIN+TRLF+ LY+
Sbjct  122  TKPVKRLWISSMEEAAIQKGFDNLLDGKNYDNLYAAALCRAKADWLIGINGTRLFTTLYQ  181

Query  184  -KNLTVGRVQTPTLKMLVDRDAKITDFKKEKYHIVHITAGGADAVSSRFSDaaeantvka  242
             K+L VGRVQTPTL +L +R+A I++F+KEK+  V++   G  A S RF+  ++A  +++
Sbjct  182  GKSLNVGRVQTPTLALLAEREAAISGFQKEKFYTVELELEGFRAASERFASKTDAGRLRT  241

Query  243  acakaqavcvsvTREKKTEQPPKLYDLTTLQREANRLFGYTAKQTLDYAQALYLKKLLTY  302
            +C    A   +V++  KTE+PPKLYDLTTLQREANRLF+YTA+QTLDY QALY K+L TY
Sbjct  242  GCVGKPATVQTVSQKEKTERPPKLYDLTTLQREANRLFDYTAQQTLDYLQALYEKRLATY  301

Query  303  PRTDSQYLTDDMLPAVESLVSGLWELVPFAKGLNLSPQFDRILNSKKVSDHHAIIPTAEF  362
            PRTDS+YLT+DM +++ +L  ++   +PFA +L+L+ +  +++++ KV+DHHAI+PT+E 
Sbjct  302  PRTDSRYLTEDMAAGLPALCQSVAAALPFAADLSLPVNAAQVIDNSKVTDHHAILPTTEA  361

Query  363  VKQGFGTLAESEkkllslicckllcAVAGPHIYEAVTATFTCAGQEFTAKGKTVLSPGWK  422
             K ++++L+ +EK++L L+  +LLCAV+ PH Y   + T+ C+G  F+AKGKT  ++GW 
Sbjct  362  AKTDLSALPSGEKNILFLVAARLLCAVGEPHTYAETAVTLECGGAVFSAKGKTETAAGWT  421

Query  423  EIERRFRSSLKTDADEDAEAVRELPELCEGQTFADVAASVTEHFTTPPKPYTEDTLLSAM  482
             +E+ F+++LK  + + +E+   LP L  GQ ++  +AS+ E  T+PP  +TEDTLLSAM
Sbjct  422  AMEQAFHATLKKKPKQ-PEPSPPLPALTKGQKLTAGGASIKEGATSPPAHFTEDTLLSAM  480

Query  483  ERAGAEDMP--EDAERKGLGTPATRAAILEKLVQMGFVQRKGKQLIPTKDGINLAVVLPE  540
            E+A+A + +  ED E+KGLGTPATRA+++EKLV+ GFV+RK KQL+PT  G +L  V+P+
Sbjct  481  EHASAKEFAKLEDVEHKGLGTPATRAGVIEKLVRSGFVERKKKQLFPTEKGTELIKVMPD  540

Query  541  ALTSPQLTAEWENRLTEIAKGQADPDEFMDGIETQARELVQTYSCISEEKQKLFQAERVP  600
            +L S +LTAEWE+RL  + +G+  P++FM GI +   ELV++Y  ++     L  + R  
Sbjct  541  TLKSVKLTAEWEERLGAVERGELSPEDFMAGITAMLTELVKSYQGVTVASAALSASGRTV  600

Query  601  IGTCPRCGEAVYEGKKNYYC----GNRACQFVMWKNDRFFEERKKAFTPKIaaallktgk  656
            IG CPRCG  V EGKK+++C    +  AC+F +WKNDRFF  + K +T K AAALLK G+
Sbjct  601  IGICPRCGKNVVEGKKSFFCEGWNAAPACDFALWKNDRFFTSKHKELTRKAAAALLKKGR  660

Query  657  vkvkglYSVKTGKTYDGTVLLADTGGKYVNYRIE  690
            V + GL+S K G  YD+ V++ DTG K+V +++E
Sbjct  661  VAMTGLFSEKKGVLYDAIVVMEDTGEKFVRFKLE  694

20) EFAU085_00720 in NC_021994


> NC_004668_R1|30|G30|29376814|NP_815968.1|Enterococcus_faecalis_V583|-|30310..32427|topB-2|EF2312|DNA 
topoisomerase III
Length=705

 Score =  604 bits (2282),  Expect = 6e-174, Method: Compositional matrix adjust.
 Identities = 360/694 (52%), Positives = 515/694 (75%), Gaps = 8/694 (1%)

Query  4    KLVIAEKPSVARSIAGVIGATEKHDGYLEGNGYLVSWCIGHLVSFADAGRYDERFKKWRY  63
            +LVIAEKPSV+ +++ V+GA  + DGY+EG G LVSWCIGHLV +A A+ YD R+ KW Y
Sbjct  2    QLVIAEKPSVGMALSKVLGAKSRGDGYMEGGGWLVSWCIGHLVELAPADAYDPRYSKWNY  61

Query  64   EDLPILPETWQYIVPDDKKQQFDVLCSLMQRPDVTGLVCATDAGREGELIFRFVYQMAGC  123
             DLPILP  WQ+ V  D K+QF+VL +L++R+DVT+L+CATDAGREGELIFR+ Y++ GC
Sbjct  62   ADLPILPKPWQFQVLPDTKKQFEVLKTLIHRADVTALICATDAGREGELIFRLTYHLCGC  121

Query  124  QKPFERLWISSMEDSAIKDGFAHLKPGGDYDPLYQSALCRAKADWLIGINATRLFSVLYH  183
             KP  RLWISSME++AI+ GF +L  G +YD LY +ALCRAKADWLIGIN+TRLF+ LY+
Sbjct  122  TKPVKRLWISSMEEAAIQKGFDNLLDGKNYDNLYAAALCRAKADWLIGINGTRLFTTLYQ  181

Query  184  -KNLTVGRVQTPTLKMLVDRDAKITDFKKEKYHIVHITAGGADAVSSRFSDaaeantvka  242
             K+L VGRVQTPTL +L +R+A I++F+KEK+  V++   G  A S RF+  ++A  +++
Sbjct  182  GKSLNVGRVQTPTLALLAEREAAISGFQKEKFYTVELELEGFRAASERFASKTDAGRLRT  241

Query  243  acakaqavcvsvTREKKTEQPPKLYDLTTLQREANRLFGYTAKQTLDYAQALYLKKLLTY  302
            +C    A   +V++  KTE+PPKLYDLTTLQREANRLF+YTA+QTLDY QALY K+L TY
Sbjct  242  GCVGKPATVQTVSQKEKTERPPKLYDLTTLQREANRLFDYTAQQTLDYLQALYEKRLATY  301

Query  303  PRTDSQYLTDDMLPAVESLVSGLWELVPFAKGLNLSPQFDRILNSKKVSDHHAIIPTAEF  362
            PRTDS+YLT+DM +++ +L  ++   +PFA +L+L+ +  +++++ KV+DHHAI+PT+E 
Sbjct  302  PRTDSRYLTEDMAAGLPALCQSVAAALPFAADLSLPVNAAQVIDNSKVTDHHAILPTTEA  361

Query  363  VKQGFGTLAESEkkllslicckllcAVAGPHIYEAVTATFTCAGQEFTAKGKTVLSPGWK  422
             K ++++L+ +EK++L L+  +LLCAV+ PH Y   + T+ C+G  F+AKGKT  ++GW 
Sbjct  362  AKTDLSALPSGEKNILFLVAARLLCAVGEPHTYAETAVTLECGGAVFSAKGKTETAAGWT  421

Query  423  EIERRFRSSLKTDADEDAEAVRELPELCEGQTFADVAASVTEHFTTPPKPYTEDTLLSAM  482
             +E+ F+++LK  + + +E+   LP L  GQ ++  +AS+ E  T+PP  +TEDTLLSAM
Sbjct  422  AMEQAFHATLKKKPKQ-PEPSPPLPALTKGQKLTAGGASIKEGATSPPAHFTEDTLLSAM  480

Query  483  ERAGAEDMP--EDAERKGLGTPATRAAILEKLVQMGFVQRKGKQLIPTKDGINLAVVLPE  540
            E+A+A + +  ED E+KGLGTPATRA+++EKLV+ GFV+RK KQL+PT  G +L  V+P+
Sbjct  481  EHASAKEFAKLEDVEHKGLGTPATRAGVIEKLVRSGFVERKKKQLFPTEKGTELIKVMPD  540

Query  541  ALTSPQLTAEWENRLTEIAKGQADPDEFMDGIETQARELVQTYSCISEEKQKLFQAERVP  600
            +L S +LTAEWE+RL  + +G+  P++FM GI +   ELV++Y  ++     L  + R  
Sbjct  541  TLKSVKLTAEWEERLGAVERGELSPEDFMAGITAMLTELVKSYQGVTVASAALSASGRTV  600

Query  601  IGTCPRCGEAVYEGKKNYYC----GNRACQFVMWKNDRFFEERKKAFTPKIaaallktgk  656
            IG CPRCG  V EGKK+++C    +  AC+F +WKNDRFF  + K +T K AAALLK G+
Sbjct  601  IGICPRCGKNVVEGKKSFFCEGWNAAPACDFALWKNDRFFTSKHKELTRKAAAALLKKGR  660

Query  657  vkvkglYSVKTGKTYDGTVLLADTGGKYVNYRIE  690
            V + GL+S K G  YD+ V++ DTG K+V +++E
Sbjct  661  VAMTGLFSEKKGVLYDAIVVMEDTGEKFVRFKLE  694

21) EUBREC_3570 in NC_012781


> NC_004668_R1|30|G30|29376814|NP_815968.1|Enterococcus_faecalis_V583|-|30310..32427|topB-2|EF2312|DNA 
topoisomerase III
Length=705

 Score =  604 bits (2281),  Expect = 8e-174, Method: Compositional matrix adjust.
 Identities = 342/697 (50%), Positives = 490/697 (71%), Gaps = 12/697 (1%)

Query  1    MKLVIAEKPSVAMALASVIGARTRKDGYVEGNGYLVSWCVGHLVGLCDASEYDEKYKKWR  60
            M+LVIAEKPSV+MAL+ V+GA++R DGY+EG G LVSWC+GHLV L  A  YD +Y KW 
Sbjct  1    MQLVIAEKPSVGMALSKVLGAKSRGDGYMEGGGWLVSWCIGHLVELAPADAYDPRYSKWN  60

Query  61   YEDLPIVPECWKHRVLEGTKKQFGILKKLMRDSKVDEVICATDAGREGELIFRLVYEQAG  120
            Y DLPI+P  W+ +VL +TKKQF +LK L++ + V  +ICATDAGREGELIFRL Y+  G
Sbjct  61   YADLPILPKPWQFQVLPDTKKQFEVLKTLIHRADVTALICATDAGREGELIFRLTYHLCG  120

Query  121  CKKPMKRLWISSMEEQAIKDGFASLKDGSCYDSLYQSALCRAKADWLVGINASRLFSVLY  180
            C KP+KRLWISSMEE AI+ GF +L DG  YD+LY +ALCRAKADWL+GIN++RLF+ LY
Sbjct  121  CTKPVKRLWISSMEEAAIQKGFDNLLDGKNYDNLYAAALCRAKADWLIGINGTRLFTTLY  180

Query  181  -NQNLKVGRVQTPTLAMIVDRNQKIKEFTKEKYYMAHIKFDEMDAVTEHFQKKEDADRVA  239
              ++L+VGRVQTPTLA++ +R+  I  F KEK+Y  ++ ++   A +E+F  K DA+R+ 
Sbjct  181  QGKSLNVGRVQTPTLALLAEREAAISGFQKEKFYTVELELEGFRAASERFASKTDAGRLR  240

Query  240  ADCMERMCEVEKDDVKEKTVRPPKLYDLTTLQREANRMFGYTAQQTLDAVQEMYEQKLVT  299
            ++C+ +   V+    KEKT RPPKLYDLTTLQREANR+F+YTAQQTLD +Q +YE++L T
Sbjct  241  TGCVGKPATVQTVSQKEKTERPPKLYDLTTLQREANRLFDYTAQQTLDYLQALYEKRLAT  300

Query  300  YPRTDSQYLTDEMGESTETLIQMLLGKMPYAEGLEYHPDVSKVLNSKKVSDHHAIIPTME  359
            YPRTDS+YLT++M+ +  +L Q + + +P+A +L    + ++V+++ KV+DHHAI+PT E
Sbjct  301  YPRTDSRYLTEDMAAGLPALCQSVAAALPFAADLSLPVNAAQVIDNSKVTDHHAILPTTE  360

Query  360  VAKADIGELKERNRKILYLISARVLTATADPYIYESHKCQITCNYHTFYLTAKKTKQEGF  419
             AK+D++ L   +++IL+L++AR+L A ++P  Y      + C    F   +K     G 
Sbjct  361  AAKTDLSALPSGEKNILFLVAARLLCAVGEPHTYAETAVTLECGGAVFSAKGKTETAAGW  420

Query  420  KAIENKLKQFFGVKIEKEEPELDIWA---GKHYGPCDSLVSEHFTQPPKQYTEDTLLSAM  476
             A+E+ +   +  K  + EP   + A   G+   + ++ + E  T PP ++TEDTLLSAM
Sbjct  421  TAMEQAFHATLKKKPKQPEPSPPLPALTKGQKLTAGGASIKEGATSPPAHFTEDTLLSAM  480

Query  477  ERAGNEELT--EDTEKKGLGTPATRAAIIEKLIQSGFVKREKKNLVPTDDGNVLITVLPD  534
            E+A+  E++  ED E KGLGTPATRA++IEKL++SGFV R KK+L PT+ G  LI V+PD
Sbjct  481  EHASAKEFAKLEDVEHKGLGTPATRAGVIEKLVRSGFVERKKKQLFPTEKGTELIKVMPD  540

Query  535  EIKSPKMTAEWEMALNHIAQNTETADEFLNGITELMQELVARYQGISEEKKNQFQGKAKG  594
             +KS K+TAEWE  L  + +   ++++F+ GIT ++ ELV  YQG++      + + ++ 
Sbjct  541  TLKSVKLTAEWEERLGAVERGELSPEDFMAGITAMLTELVKSYQGVTVA-SAALSASGRT  599

Query  595  EVIGKCPRCGADVQEGKVNFYCSDRN----CTFTLWKNDKFLASQGKKMDKTAAKKFLSK  650
             VIG CPRCG +V EGK +F+C ++N    C F+LWKND+F++S+ K + + AA  +L K
Sbjct  600  -VIGICPRCGKNVVEGKKSFFCEGWNAAPACDFALWKNDRFFTSKHKELTRKAAAALLKK  658

Query  651  GKIHYKDLVSRKTGRQYEATVEMVDPGEGNVQFNLIF  687
            G++   +L S K G  Y+A V M D GE  V+F+L F
Sbjct  659  GRVAMTGLFSEKKGVLYDAIVVMEDTGEKFVRFKLEF  695

22) CCU_07970 in NC_021018


> NC_004668_R1|30|G30|29376814|NP_815968.1|Enterococcus_faecalis_V583|-|30310..32427|topB-2|EF2312|DNA 
topoisomerase III
Length=705

 Score =  594 bits (2245),  Expect = 5e-171, Method: Compositional matrix adjust.
 Identities = 337/686 (50%), Positives = 471/686 (69%), Gaps = 14/686 (2%)

Query  1    MQLVIAEKPSVAKSIADVLGALDRQDGYFEGGGYLVSWCVGHLIELAEPESYGEQWKKWT  60
            MQLVIAEKPSV+ +++ VLGA  R DGY EGGG LVSWC+GHL+ELA +++Y+ +  KW 
Sbjct  1    MQLVIAEKPSVGMALSKVLGAKSRGDGYMEGGGWLVSWCIGHLVELAPADAYDPRYSKWN  60

Query  61   YESLPVNPEHWQYEIKEDTKEQYDVLYGLLHDSRVDEVVCATDAGREGELIFRLVYNMAS  120
            Y  LP+ P  WQ+++  DTK Q++VL  L+H + V  ++CATDAGREGELIFRL Y++ +
Sbjct  61   YADLPILPKPWQFQVLPDTKKQFEVLKTLIHRADVTALICATDAGREGELIFRLTYHLCG  120

Query  121  CKKPMKRLWISSMEESAIREGVENLKPGSDYDHLYHSALCRQEADWLVGINGTRLFTVLY  180
            C KP+KRLWISSMEE+AI+ G +NL  G +YD+LY +ALCR  ADWL+GINGTRLFT LY
Sbjct  121  CTKPVKRLWISSMEEAAIQKGFDNLLDGKNYDNLYAAALCRAKADWLIGINGTRLFTTLY  180

Query  181  GGKVLKVGRVQTPTLAMLVEREAKIMNFKKEQYFMAHILCGGVDAVTERIDNKTEAENVA  240
             GK L+VGRVQTPTLA+L EREA I  F+KE+++  ++   G  A +ER+ +KT+A  + 
Sbjct  181  QGKSLNVGRVQTPTLALLAEREAAISGFQKEKFYTVELELEGFRAASERFASKTDAGRLR  240

Query  241  GACRNGQALVTSVEKEEKTVSPPKLYDLTTLQRDANRLFGFTAKQTLEYTQSLYEKKMCT  300
             +C    A V +V + EKT  PPKLYDLTTLQR+ANRLF++TA+QTL+Y Q+LYEK++ T
Sbjct  241  TGCVGKPATVQTVSQKEKTERPPKLYDLTTLQREANRLFDYTAQQTLDYLQALYEKRLAT  300

Query  301  YPRTDSQYLSDDMEQTAGNVIEAIFSSILFEENRMFNPDIKRVLNSKKVTDHHAIIPTME  360
            YPRTDS+YL++DM      + +++ +++ F  +  +  +  +V+++ KVTDHHAI+PT E
Sbjct  301  YPRTDSRYLTEDMAAGLPALCQSVAAALPFAADLSLPVNAAQVIDNSKVTDHHAILPTTE  360

Query  361  IAKADLAALPETERKILSLVANRLLCATGEKHLYETVKAELSCGGYTFTTSGKSVLKNGW  420
             AK+DL+ALP  E++IL LVA RLLCA GE H Y      L CGG  F++ GK+    GW
Sbjct  361  AAKTDLSALPSGEKNILFLVAARLLCAVGEPHTYAETAVTLECGGAVFSAKGKTETAAGW  420

Query  421  KDFEDAFKRSFKATEEKEQEDKKLPELSEGQTFDGVQTKISEHYTTPPKHFTEDSLLSAM  480
               E+AF  ++K    + +    LP L+ GQ + +  + I E  T+PP HFTED+LLSAM
Sbjct  421  TAMEQAFHATLKKKPKQPEPSPPLPALTKGQKLTAGGASIKEGATSPPAHFTEDTLLSAM  480

Query  481  ERAGNEDMS--DDVERKGLGTPATRADIIEKLVKDGFVKREKKQMLPTEDGMKLITVLPD  538
            E+A+  + +  +DVE+KGLGTPATRA++IEKLV+ GFV R KKQ++PTE G  LI V+PD
Sbjct  481  EHASAKEFAKLEDVEHKGLGTPATRAGVIEKLVRSGFVERKKKQLFPTEKGTELIKVMPD  540

Query  539  VVKSSKLTADWENALTLVAKGEMEREDFMADIETMESDLIHTYHEVSDEQKKMFAQEQKV  598
             +KS KLTA+WE+ L  V +GE+  EDFMA+I +M ++L+ +Y+ V+     + A  + V
Sbjct  541  TLKSVKLTAEWEERLGAVERGELSPEDFMAGITAMLTELVKSYQGVTVASAALSASGRTV  600

Query  599  LGKCPNCGGEVVKGKYGAFCKN-----KCGMNV---SRIMGV---ALSDEQVESLLAGKK  647
            +G CP CG +VV GK + FC        C+  +    R+       L+     +LL   +
Sbjct  601  IGICPRCGKNVVEGKKSFFCEGWNAAPACDFALWKNDRFFTSKHKELTRKAAAALLKKGR  660

Query  648  TLLKGI-TSKAGKKYDAYIIPSGTEE  672
              + G+ + K G  YDA ++  +T E
Sbjct  661  VAMTGLFSEKKGVLYDAIVVMEDTGE  686

23) RHOM_15375 in NC_015977


> NC_004668_R1|30|G30|29376814|NP_815968.1|Enterococcus_faecalis_V583|-|30310..32427|topB-2|EF2312|DNA 
topoisomerase III
Length=705

 Score =  583 bits (2203),  Expect = 1e-167, Method: Compositional matrix adjust.
 Identities = 319/621 (52%), Positives = 447/621 (72%), Gaps = 3/621 (0%)

Query  1    MQLVVTEKPSVAQAISHVIGAKERKDGYMEGNGFLVSWCVGHLVELAQPEMYSEAWKKWS  60
            MQLV++EKPSV+ A+S V+GAK R DGYMEG G LVSWC+GHLVELA ++ Y     KW+
Sbjct  1    MQLVIAEKPSVGMALSKVLGAKSRGDGYMEGGGWLVSWCIGHLVELAPADAYDPRYSKWN  60

Query  61   YESLPMIPEQWQHEVKKETATQYKILKNLMHDTRVESVVCATDAGREGELIFRLVYEQAG  120
            Y  LP++P  WQ +V  +T  Q+ +LK L+H + V +++CATDAGREGELIFRL Y+  G
Sbjct  61   YADLPILPKPWQFQVLPDTKKQFEVLKTLIHRADVTALICATDAGREGELIFRLTYHLCG  120

Query  121  CRKPMKRLWISSMEESAIRDGFENLKPGSDYDSLYQSALCRQQADWLVGLNGTRLFTVLY  180
            C KP+KRLWISSMEE+AI+ GF+NL  G +YD+LY +ALCR +ADWL+G+NGTRLFT LY
Sbjct  121  CTKPVKRLWISSMEEAAIQKGFDNLLDGKNYDNLYAAALCRAKADWLIGINGTRLFTTLY  180

Query  181  GGKVLKVGRVQTPTLAMLVDREVKIMNFEKEQYYMAHILMDGIDAMTERIDDKARAESIA  240
             GK L+VGRVQTPTLA+L +RE  I  F+KE++Y  ++ ++G+ A +ER+  K+ A  + 
Sbjct  181  QGKSLNVGRVQTPTLALLAEREAAISGFQKEKFYTVELELEGFRAASERFASKTDAGRLR  240

Query  241  AACESQSGVVRSVIKENKSVAPPKLYDLTTLQRDANRIFGFTAKQTLEYTQSLYEKKLVT  300
            ++C ++++ V++V + +K+  PPKLYDLTTLQR+ANR+F++TA+QTL+Y Q+LYEK+L T
Sbjct  241  TGCVGKPATVQTVSQKEKTERPPKLYDLTTLQREANRLFDYTAQQTLDYLQALYEKRLAT  300

Query  301  YPRTDSQYLSDDMEETAKAVIGAVYQAILFEEQTGAEPDIKRVLNSKKVTDHHAIIPTIE  360
            YPRTDS+YL++DM     A+  +V  A+ F  + +   +  +V+++ KVTDHHAI+PT E
Sbjct  301  YPRTDSRYLTEDMAAGLPALCQSVAAALPFAADLSLPVNAAQVIDNSKVTDHHAILPTTE  360

Query  361  ITKTDLSAVPEGEMKILSLVANRLLCATGKKQLYETVKAEFSCGGYSFHVSGKTVLQNGW  420
             +KTDLSA+P GE +IL LVA RLLCA G  + Y      + CGG  F   GKT    GW
Sbjct  361  AAKTDLSALPSGEKNILFLVAARLLCAVGEPHTYAETAVTLECGGAVFSAKGKTETAAGW  420

Query  421  KEFEAALKRTYRVektdedkeekkLPELSEGMTFPVIQTKVTEHFTQPPKHFTEDSLLSA  480
               E A+  T +  K  +      LP L+ G  +    + + E  T PP HFTED+LLSA
Sbjct  421  TAMEQAFHATLK-KKPKQPEPSPPLPALTKGQKLTAGGASIKEGATSPPAHFTEDTLLSA  479

Query  481  MERAGAEDMG--DEVERKGLGTPATRADIIEKLVKDGFVKREKKQMLPTEDGMKLITVLP  538
            ME+A+A + +  ++VE+KGLGTPATRA++IEKLV+ GFV R KKQ++PTE G  LI V+P
Sbjct  480  MEHASAKEFAKLEDVEHKGLGTPATRAGVIEKLVRSGFVERKKKQLFPTEKGTELIKVMP  539

Query  539  DMVKSPKLTADWENTLTLVEKGEYTMQEFMDGIEDMVRELVQTYHSISDDQKSLFGTMQE  598
            D +KS KLTA+WE+ L  VE+GE + ++FM GI  M+ ELV++Y++++    +L ++ + 
Sbjct  540  DTLKSVKLTAEWEERLGAVERGELSPEDFMAGITAMLTELVKSYQGVTVASAALSASGRT  599

Query  599  VLGKCPKCGSDVVKGKFGAYC  619
            V+G CP+CG +VV GK + +C
Sbjct  600  VIGICPRCGKNVVEGKKSFFC  620

24) CK5_35660 in NC_021022


> NC_004668_R1|30|G30|29376814|NP_815968.1|Enterococcus_faecalis_V583|-|30310..32427|topB-2|EF2312|DNA 
topoisomerase III
Length=705

 Score =  582 bits (2197),  Expect = 3e-167, Method: Compositional matrix adjust.
 Identities = 350/704 (50%), Positives = 481/704 (69%), Gaps = 15/704 (2%)

Query  5    LVIAEKPSVAQSLAKNLSAYQRKDGYLEGNSCIVSWCLGHLAEYAPPEIYDEKYAKWQFE  64
            LVIAEKPSV+ +L+K L+A  R DGY+EG + +VSWC+GHL E AP++ YD +Y+KW++ 
Sbjct  3    LVIAEKPSVGMALSKVLGAKSRGDGYMEGGGWLVSWCIGHLVELAPADAYDPRYSKWNYA  62

Query  65   DLPIIPKVWKVQVSEDKKKQFDVLCNLINRADVAYLVNGCDAGREGELIFKRVYDLAGCQ  124
            DLPI+PK W+ QV  D KKQF+VL  LI+RADV+ L+ + DAGREGELIF+  Y+L GC 
Sbjct  63   DLPILPKPWQFQVLPDTKKQFEVLKTLIHRADVTALICATDAGREGELIFRLTYHLCGCT  122

Query  125  KPVKRLWISSMEDEAIQKGFQSLTDGREYAGLCNAAVCRAQADWLIGMNATRAYTTRY-F  183
            KPVKRLWISSME+ AIQKGF++L DG++Y  L  AA+CRA+ADWLIG+N+TR +TT Y  
Sbjct  123  KPVKRLWISSMEEAAIQKGFDNLLDGKNYDNLYAAALCRAKADWLIGINGTRLFTTLYQG  182

Query  184  KRLVVGRVQTPTLAMLTERKEKIEHFKKEAYYKVSLSDGKLMVTSESIPLEMEAEELRKL  243
            K L VGRVQTPTLA+L+ER   I  F+KE +Y V L    +  +SE ++   +A  LR  
Sbjct  183  KSLNVGRVQTPTLALLAEREAAISGFQKEKFYTVELELEGFRAASERFASKTDAGRLRTG  242

Query  244  CDGTEALVTRVKREQKKTFPPKLYDLTSLQREANRFFGYTAQKTLDMLQELYEEKMVTYP  303
            C G  A V  V + +K   PPKLYDLT+LQREANR+F+YTAQ+TLD LQ LYE ++ TYP
Sbjct  243  CVGKPATVQTVSQKEKTERPPKLYDLTTLQREANRLFDYTAQQTLDYLQALYEKRLATYP  302

Query  304  RTDSQYVTEDMKETVKMLAEGMTGFLPFLESGQTRGNIDRVVNNAKVSDHHAILPTKEAM  363
            RTDS+Y+TEDM   +  L +++++ LPF        N  +V++N+KV+DHHAILPT EA 
Sbjct  303  RTDSRYLTEDMAAGLPALCQSVAAALPFAADLSLPVNAAQVIDNSKVTDHHAILPTTEAA  362

Query  364  EKGMGGLSSGKKNLLMLIGQQLVQATGEEYLYEQTEISVQCKEHEFAAKGKLSVQMGFKE  423
              ++++L+SG KN+L L++ +L+ A GE   Y +T ++++C    F+AKGK     G   
Sbjct  363  KTDLSALPSGEKNILFLVAARLLCAVGEPHTYAETAVTLECGGAVFSAKGKTETAAGWTA  422

Query  424  VEEAFRKYCVKDKKSDEPDNKTELSEGYEEGMILASVKAEKSTHYTSPPKMFTEDTLLAA  483
            +E+AF+      KK+ +P+    L+ +   G  L++  A      TSPP  FTEDTLL+A
Sbjct  423  MEQAFHA--TLKKKPKQPEPSPPLP-ALTKGQKLTAGGASIKEGATSPPAHFTEDTLLSA  479

Query  484  METAGNKEFD--SETEKKGLGTPATRANIIEKLVSSGYAERKGKQILPTVAGCELIHVMP  541
            ME A+ KEF    + E KGLGTPATRA +IEKLV SG+ ERK KQ++PT  G ELI VMP
Sbjct  480  MEHASAKEFAKLEDVEHKGLGTPATRAGVIEKLVRSGFVERKKKQLFPTEKGTELIKVMP  539

Query  542  ENLKSASLTAEWENLLLMMEKGKIQEDEFMNGIVSMINEILSLCRAIPEEERNRFQTARE  601
            + LKS  LTAEWE+ L  +E+G +  ++FM GI +M+ E++   +++         ++R 
Sbjct  540  DTLKSVKLTAEWEERLGAVERGELSPEDFMAGITAMLTELVKSYQGVTVASAALSASGRT  599

Query  602  VIGKCPVCGSDVYEGKTNYYCSDR----SCQFALWKSNRFLESMKKSMDKKMAVELLKKG  657
            VIG CP CG +V EGK +++C ++    +C+FALWK++RF+ S  K + +K A  LLKKG
Sbjct  600  VIGICPRCGKNVVEGKKSFFCEGWNAAPACDFALWKNDRFFTSKHKELTRKAAAALLKKG  659

Query  658  RTHVKGLYSKKKDSKFDADLVLGVEEGK-ARFSLEF----PKKK  696
            R  + GL+S KK+  +DA +V+     K  RF LEF    PKKK
Sbjct  660  RVAMTGLFSEKKGVLYDAIVVMEDTGEKFVRFKLEFDNNTPKKK  703

25) FP2_00540 in NC_021042


> NC_004668_R1|30|G30|29376814|NP_815968.1|Enterococcus_faecalis_V583|-|30310..32427|topB-2|EF2312|DNA 
topoisomerase III
Length=705

 Score =  580 bits (2191),  Expect = 8e-167, Method: Compositional matrix adjust.
 Identities = 346/627 (56%), Positives = 462/627 (74%), Gaps = 21/627 (3%)

Query  1    MSYAKVLGATNRQDGYLEGNGYLVSWCIGHLVELAPPNVYDEKFIKWSIADLPILPEKWQ  60
            M+ +KVLGA +R DGY+EG G LVSWCIGHLVELAP++ YD ++ KW+ ADLPILP  WQ
Sbjct  13   MALSKVLGAKSRGDGYMEGGGWLVSWCIGHLVELAPADAYDPRYSKWNYADLPILPKPWQ  72

Query  61   YLVSASTKKQFGVLQKLMHRPDVDSIVNSCDSGREGELIFRLVYQQAGCKKPFSRLWLSS  120
            + V + TKKQF VL+ L+HR+DV +++ + D+GREGELIFRL Y+  GC KP  RLW+SS
Sbjct  73   FQVLPDTKKQFEVLKTLIHRADVTALICATDAGREGELIFRLTYHLCGCTKPVKRLWISS  132

Query  121  MEENAIRESFAHLKPSTEYDALYNAALCRERADWIVGINASRLFSCLYN-QPLAVGRVMT  179
            MEE AI+ +F +L  + +YD LY AALCR +ADW++GIN++RLF+ LY+ ++L VGRV T
Sbjct  133  MEEAAIQKGFDNLLDGKNYDNLYAAALCRAKADWLIGINGTRLFTTLYQGKSLNVGRVQT  192

Query  180  PVLAMTVVREAAISAFVPEKFYTVALTLADGGTASSKRFAQKADAELLLSKCRKEGRVTV  239
            P LA+   REAAIS+F  EKFYTV L L +G  A+S RFA K+DA  L + C      TV
Sbjct  193  PTLALLAEREAAISGFQKEKFYTVELEL-EGFRAASERFASKTDAGRLRTGC-VGKPATV  250

Query  240  QKMERKEKSENPPQLYDLTALQRDANRLLGFTAQQTLDYAQSLYEKRLITYPRTDSRFLT  299
            Q + +KEK+E PP+LYDLT+LQR+ANRL+++TAQQTLDY Q+LYEKRL TYPRTDSR+LT
Sbjct  251  QTVSQKEKTERPPKLYDLTTLQREANRLFDYTAQQTLDYLQALYEKRLATYPRTDSRYLT  310

Query  300  EDMAASLPGL--VTDTGRAFTVEESFPIHVQQVINGSKVTDHHALLPTKSMANADLAALP  357
            EDMAA+LP+L     ++ +F+ + S+P++  QVI+ SKVTDHHA+LPT   A++DL+ALP
Sbjct  311  EDMAAGLPALCQSVAAALPFAADLSLPVNAAQVIDNSKVTDHHAILPTTEAAKTDLSALP  370

Query  358  AGERNVLRLIAARLLCAVGEPHRYAETTLTTICAGEEFSAKGKVVLSDGWKAMERKMLGE  417
            +GE+N+L L+AARLLCAVGEPH YAET++T  C+G  FSAKGK   + GW AME+   + 
Sbjct  371  SGEKNILFLVAARLLCAVGEPHTYAETAVTLECGGAVFSAKGKTETAAGWTAMEQAFHAT  430

Query  418  LLGKQKEP---AVLPDVQEQSRCSVSGAELKEGQTSPPKHFTEDLLLHAMETASADSMP-  473
            L  K K+P   + LP +    + + +GA +KEG TSPP HFTED LL AME ASA   + 
Sbjct  431  LKKKPKQPEPSPPLPALTKGQKLTAGGASIKEGATSPPAHFTEDTLLSAMEHASAKEFAK  490

Query  474  -EGVERQGIGTPATRAATIEKLVQKGFLERKGSKKTKVLLPTDKGKALITVMPEEIQSAD  532
             E+VE++G+GTPATRA+ IEKLV+ GF+ER    K K L+PT+KG  LI VMP+ ++S  
Sbjct  491  LEDVEHKGLGTPATRAGVIEKLVRSGFVER----KKKQLFPTEKGTELIKVMPDTLKSVK  546

Query  533  MTADWEAKLLQIERGEMEPSEFMTEINMMITELVKNTEMKKGANALMKS---KIIGVCPN  589
            +TA+WE +L  +ERGE+ P +FM+ I  M+TELVK+ +    A+A + +    +IG+CP 
Sbjct  547  LTAEWEERLGAVERGELSPEDFMAGITAMLTELVKSYQGVTVASAALSASGRTVIGICPR  606

Query  590  CGANVVEREKGWFCENRE----CRFVF  612
            CG NVVE  K+ FCE ++    C F +
Sbjct  607  CGKNVVEGKKSFFCEGWNAAPACDFAL  633

26) topB in NC_018867


> NC_004668_R1|30|G30|29376814|NP_815968.1|Enterococcus_faecalis_V583|-|30310..32427|topB-2|EF2312|DNA 
topoisomerase III
Length=705

 Score =  574 bits (2167),  Expect = 8e-165, Method: Compositional matrix adjust.
 Identities = 364/704 (52%), Positives = 512/704 (73%), Gaps = 21/704 (2%)

Query  1    MNLVIAEKPSVAQSIATVLGATKRQDGYLEGNSYIVSWCVGHLVELATADTYDERYAKWE  60
            M+LVIAEKPSV+ +++ VLGA  R DGY+EG + +VSWC+GHLVELA AD+YD RY+KW+
Sbjct  1    MQLVIAEKPSVGMALSKVLGAKSRGDGYMEGGGWLVSWCIGHLVELAPADAYDPRYSKWN  60

Query  61   YADLPILPENWQYSISKGKEKQVKILKELANRKDVAVITSATDAGREGELIFRLVYEKIG  120
            YADLPILP  WQ+ +  +  KQ  +LK L +R DV+ +  ATDAGREGELIFRL Y+  G
Sbjct  61   YADLPILPKPWQFQVLPDTKKQFEVLKTLIHRADVTALICATDAGREGELIFRLTYHLCG  120

Query  121  CKKPVKRLWISSMEESAISEGFKALRDSTYYDALYQVALCRAKADWIVGINATRLFSVLY  180
            C KPVKRLWISSMEE+AI  GF  L D+  YD LY  ALCRAKADW++GIN+TRLF+ LY
Sbjct  121  CTKPVKRLWISSMEEAAIQKGFDNLLDGKNYDNLYAAALCRAKADWLIGINGTRLFTTLY  180

Query  181  -GQTLNVGRVMSPTLAMIVEREAAISAFKPEPFYTVLLDCGTFILSCEKLTDRQAAEDLR  239
             G++LNVGRV +PTLA++ EREAAIS+F+ E FYTV L+   F  + E+++ +  A  LR
Sbjct  181  QGKSLNVGRVQTPTLALLAEREAAISGFQKEKFYTVELELEGFRAASERFASKTDAGRLR  240

Query  240  KACDGQTIAIHSVeskeksekppkLYDLTTLQREANRQLGFTAEQTLSYAQSLYEKKLVT  299
             +C G+  ++++V  KEK+E+PPKLYDLTTLQREANR +++TA+QTL Y Q+LYEK+L T
Sbjct  241  TGCVGKPATVQTVSQKEKTERPPKLYDLTTLQREANRLFDYTAQQTLDYLQALYEKRLAT  300

Query  300  YPRTDSRYLTSDMSESTPAVAKAAAGIF-MPKNLEPSIFMEQVTDNGKVSDHHAIIPTMN  358
            YPRTDSRYLT DM+ + PA+ ++ A+ +  + +L  ++   QV DN+KV+DHHAI+PT +
Sbjct  301  YPRTDSRYLTEDMAAGLPALCQSVAAALPFAADLSLPVNAAQVIDNSKVTDHHAILPTTE  360

Query  359  IQDCDLYSLPFGEREVLLLISLRLACAVNESCKYEETTVTAIVSGAEFTAKGKTILSEGF  418
                DL +LP GE+++L+L++ RL CAV E+  Y ET+VT   +GA F+AKGKT  + G 
Sbjct  361  AAKTDLSALPSGEKNILFLVAARLLCAVGEPHTYAETAVTLECGGAVFSAKGKTETAAGW  420

Query  419  RGIEKSYHA-MQKDKQPVEKEKVLPSITTGQTFDT-KAMIKEGKTSPPKHFTDDTIlaam  476
             ++E+++HA ++K  +  E    LP++T GQ + +  A IKEG TSPP HFT+DT+L+AM
Sbjct  421  TAMEQAFHATLKKKPKQPEPSPPLPALTKGQKLTAGGASIKEGATSPPAHFTEDTLLSAM  480

Query  477  enannal----eDSERKGIGTPATRAGilekliktelleRKG--DKKTKHFLPTQKGVSL  530
            E+A+       ED E+KG+GTPATRAG        E L R G  ++K K+++PT+KG  L
Sbjct  481  EHASAKEFAKLEDVEHKGLGTPATRAG------VIEKLVRSGFVERKKKQLFPTEKGTEL  534

Query  531  ITVLPEAIQSPQLTAEWEEKLKQIEHGLLSPDSFLQEISQMTKSLIRTYEVIK-GSDVLF  589
            I V+P++++S +LTAEWEE+L  +E+G LSP+ F+  I+ M   L+++Y+ +  +S  L 
Sbjct  535  IKVMPDTLKSVKLTAEWEERLGAVERGELSPEDFMAGITAMLTELVKSYQGVTVASAALS  594

Query  590  PSVQEAIGKCPRCGNDVIENQKGFCC----LNKTCGFALWKENkfftakkkkltktIAVE  645
            +S +  IG CPRCG++V+E +K+F C       +C+FALWK+++FFT+K K LT+  A  
Sbjct  595  ASGRTVIGICPRCGKNVVEGKKSFFCEGWNAAPACDFALWKNDRFFTSKHKELTRKAAAA  654

Query  646  LLKNGKAKLPGCYSEKTGKTYDAIVLIDETDSKYVNFKMEFPAN  689
            LLK+G+  + G +SEK G  YDAIV++++T+ K+V FK+EF  N
Sbjct  655  LLKKGRVAMTGLFSEKKGVLYDAIVVMEDTGEKFVRFKLEFDNN  698

27) RBR_21180 in NC_021013


> NC_004668_R1|30|G30|29376814|NP_815968.1|Enterococcus_faecalis_V583|-|30310..32427|topB-2|EF2312|DNA 
topoisomerase III
Length=705

 Score =  551 bits (2078),  Expect = 6e-158, Method: Compositional matrix adjust.
 Identities = 310/612 (51%), Positives = 442/612 (73%), Gaps = 10/612 (1%)

Query  1    MHRADVSEVVNACDAGREGELIFRFVYEVAGCKKPMRRLWISSMEDGAIKAGFASLKDGR  60
            +HRADV+ ++ A DAGREGELIFR+ Y++ GC KP++RLWISSME++AI+ GF +L DG+
Sbjct  90   IHRADVTALICATDAGREGELIFRLTYHLCGCTKPVKRLWISSMEEAAIQKGFDNLLDGK  149

Query  61   DYGALFASALCRAKADWLIGINATRLFSCLY-GKTLNVGRVQTPTLKMLTDRDAAISHFQ  119
            +Y+ L+A+ALCRAKADWLIGIN+TRLF+ LY GK+LNVGRVQTPTL +L++R+AAIS FQ
Sbjct  150  NYDNLYAAALCRAKADWLIGINGTRLFTTLYQGKSLNVGRVQTPTLALLAEREAAISGFQ  209

Query  120  KEKYYHVRLDLSGADAASERISDKAEADALKGACEAGKAVCVSLTREKKTAAPPKLFDLT  179
            KEK+Y V L+L G  AASER++ K++A+ L+ +C +  A   ++++  KT  PPKL+DLT
Sbjct  210  KEKFYTVELELEGFRAASERFASKTDAGRLRTGCVGKPATVQTVSQKEKTERPPKLYDLT  269

Query  180  SLQRETNRIFGYTAKQTLDLAQSLYEKRLLTYPRTDSSFLTDDMGGTAADIIALLCEKLP  239
            +LQRE+NR+F+YTA+QTLD  Q+LYEKRL TYPRTDS +LT+DM++  + +   +   LP
Sbjct  270  TLQREANRLFDYTAQQTLDYLQALYEKRLATYPRTDSRYLTEDMAAGLPALCQSVAAALP  329

Query  240  FMAGADFTPEIAKVLDSKKVSDHHAIIPTMELAKADPDALPESEKNILTLAGARLLFATA  299
            F A+  +  + A+V+D+ KV+DHHAI+PT E AK+D  ALP +EKNIL L +ARLL A +
Sbjct  330  FAADLSLPVNAAQVIDNSKVTDHHAILPTTEAAKTDLSALPSGEKNILFLVAARLLCAVG  389

Query  300  EPHIYEAVTAVFSCAGTDFTARGKTVLAEGWKELERRYRATLKDKPEAEDGENEGVTLPE  359
            EPH Y   +  + C+G+ F+A+GKT  A GW  +E+ ++ATLK KP   +    +  LP 
Sbjct  390  EPHTYAETAVTLECGGAVFSAKGKTETAAGWTAMEQAFHATLKKKPKQPEP---SPPLPA  446

Query  360  LSEGQNFPNPAAKVTEHTTTPPKPHSEASLLSAMERAGNGDTD--PDAERRGLGTPATRA  417
            L+ GQ++   +A + E +T+PP   +E +LLSAME+A+  +     D E++GLGTPATRA
Sbjct  447  LTKGQKLTAGGASIKEGATSPPAHFTEDTLLSAMEHASAKEFAKLEDVEHKGLGTPATRA  506

Query  418  AVIEKLVKGGFAERKGKQLIPTQNGAALISVLPDMLTSPQLTAEWENNLTQIAKGAADPG  477
            +VIEKLV++GF ERK KQL+PT++G+ LI V+PD L S +LTAEWE+ L  + +G   P 
Sbjct  507  GVIEKLVRSGFVERKKKQLFPTEKGTELIKVMPDTLKSVKLTAEWEERLGAVERGELSPE  566

Query  478  EFLSGIEAMARELVQTHAAALDGKKDLFREEKPSVGKCPRCGSPVHEGKKNYYC----SN  533
            +F++GI AM  ELV++  +   +   L    +  +G CPRCG  V EGKK+++C    + 
Sbjct  567  DFMAGITAMLTELVKSYQGVTVASAALSASGRTVIGICPRCGKNVVEGKKSFFCEGWNAA  626

Query  534  KECAFVMWKNDRFFEERKTAFSAKIAAALLKSGKVNVKKLYSPKTGKTYDGTIVLADTGG  593
              C F +WKNDRFF  +   ++ K AAALLK G+V +  L+S K G  YD+ +V+ DTG 
Sbjct  627  PACDFALWKNDRFFTSKHKELTRKAAAALLKKGRVAMTGLFSEKKGVLYDAIVVMEDTGE  686

Query  594  KYVNYRIEVQKN  605
            K+V +++E ++N
Sbjct  687  KFVRFKLEFDNN  698

28) CK5_04590 in NC_021022


> NC_004668_R1|30|G30|29376814|NP_815968.1|Enterococcus_faecalis_V583|-|30310..32427|topB-2|EF2312|DNA 
topoisomerase III
Length=705

 Score =  544 bits (2055),  Expect = 6e-156, Method: Compositional matrix adjust.
 Identities = 332/702 (48%), Positives = 472/702 (68%), Gaps = 11/702 (1%)

Query  5    LVIAEKPSVAQSYAKNLSAYKKEDGYLEGESCIVSWCLGHLAEYAQPEEYDPKYEKWQFD  64
            LVIAEKPSV+ + +K L+A  + DGY+EG + +VSWC+GHL E A ++ YDP+Y KW++ 
Sbjct  3    LVIAEKPSVGMALSKVLGAKSRGDGYMEGGGWLVSWCIGHLVELAPADAYDPRYSKWNYA  62

Query  65   DLPILPQVWKLKVSRDKKKQFDVLKSLMNRADVDYLVNGCDAGREGELIFQRVYDLAGCR  124
            DLPILP+ W+++V  D KKQF+VLK+L++RADV  L+ + DAGREGELIF+  Y+L GC 
Sbjct  63   DLPILPKPWQFQVLPDTKKQFEVLKTLIHRADVTALICATDAGREGELIFRLTYHLCGCT  122

Query  125  KPVKRLWISSMEDTAIRTGFQTMKGAEEYRNICMAAVCRAQADWLIGMNGTRAYTTCY-F  183
            KPVKRLWISSME++AI+ GF+ + ++ +Y N+  AA+CRA+ADWLIG+NGTR +TT Y  
Sbjct  123  KPVKRLWISSMEEAAIQKGFDNLLDGKNYDNLYAAALCRAKADWLIGINGTRLFTTLYQG  182

Query  184  KRLVVGRVQTPTLAMLAERQDKIEHFQKEAFYKVALTDGRLTVVSENIANEEAADLLASL  243
            K L VGRVQTPTLA+LAER+  I  FQKE FY V L    +   SE +A+   A+ L + 
Sbjct  183  KSLNVGRVQTPTLALLAEREAAISGFQKEKFYTVELELEGFRAASERFASKTDAGRLRTG  242

Query  244  CMGSEAVITQVKKEQKKAFPPKLYDLTSLQREANRYFGYTAKKTLDMLQELYEEKLVTYP  303
            C+G  A +  V + +K   PPKLYDLT+LQREANR F+YTA++TLD LQ LYE +L TYP
Sbjct  243  CVGKPATVQTVSQKEKTERPPKLYDLTTLQREANRLFDYTAQQTLDYLQALYEKRLATYP  302

Query  304  RTDSQFVTEDMRDTVEELVGKMPVLLPFLDYGQLGHNITRVINNAKVSDHHAILPTKEAV  363
            RTDS+++TEDM   +  L   ++  LPF     L  N ++VI+N+KV+DHHAILPT EA 
Sbjct  303  RTDSRYLTEDMAAGLPALCQSVAAALPFAADLSLPVNAAQVIDNSKVTDHHAILPTTEAA  362

Query  364  EKGISDLPADKKNLMMLVCQQLVQATGEEYQYEQTDITVKCQEHDFTARGKVPVQMGFKE  423
              ++S LP++ KN++ LV  +L+ A GE   Y +T +T+ C    F+A+GK     G   
Sbjct  363  KTDLSALPSGEKNILFLVAARLLCAVGEPHTYAETAVTLECGGAVFSAKGKTETAAGWTA  422

Query  424  AGNAFKNQCVKAkpeeeteketSIPYSYEEGMTLSPVKAEKTVHFTSPPKPFNEDTLLAA  483
              +AF  +    K   + E   ++P +   G  L++  A      TSPP  F EDTLL+A
Sbjct  423  MEQAF--HATLKKKPKQPEPSPPLP-ALTKGQKLTAGGASIKEGATSPPAHFTEDTLLSA  479

Query  484  METAGNKDFD--SETEKKGLGTPATKAGIIEKLVSSGYAVRKGKQILPSTEGRELVNVMP  541
            ME A+ K+F    + E KGLGTPAT+AG+IEKLV SG+  RK KQ++P+  G EL++VMP
Sbjct  480  MEHASAKEFAKLEDVEHKGLGTPATRAGVIEKLVRSGFVERKKKQLFPTEKGTELIKVMP  539

Query  542  AYLKSAAMTAEWENQLLMMEKGQITDTQFMGEITSLVGKILSVCREIPEVERRRFQKARE  601
              LKS  +TAEWE++L  +E+G+++  +FM+ IT+++  ++   + +          +R 
Sbjct  540  DTLKSVKLTAEWEERLGAVERGELSPEDFMAGITAMLTELVKSYQGVTVASAALSASGRT  599

Query  602  VIGKCPVCGSDVYEGKQNFYCSNRQ----CDFALWKENRFLGSMEKTLDKKMAVELLDKA  657
            VIG CP CG +V EGK++F+C  ++    CDFALWK++RF+ S +K L +K A  LL K+
Sbjct  600  VIGICPRCGKNVVEGKKSFFCEGWNAAPACDFALWKNDRFFTSKHKELTRKAAAALLKKG  659

Query  658  CTHVKGLYSRKKDIKFDADLLLTLEDGK-PRFHLEFPKKKKK  698
               + GL+S KK++ +DA +++   + K  RF LEF ++  K
Sbjct  660  RVAMTGLFSEKKGVLYDAIVVMEDTGEKFVRFKLEFDNNTPK  701

29) CC1_26110 in NC_021009


> NC_004668_R1|30|G30|29376814|NP_815968.1|Enterococcus_faecalis_V583|-|30310..32427|topB-2|EF2312|DNA 
topoisomerase III
Length=705

 Score =  515 bits (1943),  Expect = 4e-147, Method: Compositional matrix adjust.
 Identities = 322/689 (47%), Positives = 471/689 (69%), Gaps = 12/689 (1%)

Query  1    MYLVIAEKPSVSKAIAEVIGAQEREDGYLQGTDCMVSWCFGHLAEYVSPDAYDEKFNQWR  60
            M LVIAEKPSV+ A++ V+GA+ R DGY++G + +VSWC+GHL E  ++DAYD ++++W 
Sbjct  1    MQLVIAEKPSVGMALSKVLGAKSRGDGYMEGGGWLVSWCIGHLVELAPADAYDPRYSKWN  60

Query  61   YEDLPIIPKDWKVTVSEDKKDQFYILKRLLNSPEIEYVVNACDAGREGELIFKHVYDLSG  120
            Y DLPI+PK W+  V  D K QF +LK L++ +++  ++ A DAGREGELIF+  Y+L G
Sbjct  61   YADLPILPKPWQFQVLPDTKKQFEVLKTLIHRADVTALICATDAGREGELIFRLTYHLCG  120

Query  121  SKKPVKRLWISSLEDSAILDGMQHLRSAEEYRHLAEAAVCRSQADWLVGMNATRAYTTKY  180
              KPVKRLWISS+E++AI  G ++L  + +Y +L  AA+CR++ADWL+G+N+TR +TT Y
Sbjct  121  CTKPVKRLWISSMEEAAIQKGFDNLLDGKNYDNLYAAALCRAKADWLIGINGTRLFTTLY  180

Query  181  -FKKLTVGRVQTPTLAMLVERAGQISNFQKEKYFNVELDCDGIPAVKPKIFDPDEAEQLR  239
              K L VGRVQTPTLA+L ER + IS FQKEK++ VEL+ +G+ A   ++    +A +LR
Sbjct  181  QGKSLNVGRVQTPTLALLAEREAAISGFQKEKFYTVELELEGFRAASERFASKTDAGRLR  240

Query  240  SRCQGSEAIvtavketekkvkaPKLYDLTTLQREANRIYGMTAKQTLDTAQSLYEKKLIT  299
            + C G  A V +V + EK  ++PKLYDLTTLQREANR+++ TA+QTLD  Q+LYEK+L T
Sbjct  241  TGCVGKPATVQTVSQKEKTERPPKLYDLTTLQREANRLFDYTAQQTLDYLQALYEKRLAT  300

Query  300  YPRTDSQYLTEDMEQTARNVVRQIYEKYQLTGPFDQPEQPDVKKVMNNSKVTDHHAIIPT  359
            YPRTDS+YLTEDM      + + +     +++ +  P ++   +V++NSKVTDHHAI+PT
Sbjct  301  YPRTDSRYLTEDMAAGLPALCQSVAAALPFAADLSLPVNAA--QVIDNSKVTDHHAILPT  358

Query  360  MELASCHLDELKSWEEKILFLIAVHTVMAMSKDHIYqeteievecqeeiFKAKGKIVLQD  419
             E A  +L  L S E +ILFL+A + + A++  H Y ET + +EC   +F AKGK     
Sbjct  359  TEAAKTDLSALPSGEKNILFLVAARLLCAVGEPHTYAETAVTLECGGAVFSAKGKTETAA  418

Query  420  GWKLFENCFKNKDRMAIVDPDQEMKERMPKVTQGQTFYAVDAEKTEHFTSPPKPYSEDTL  479
            GW   E+ F    +    +P+      +P +T+GQ + A +A   E  TSPP  ++EDTL
Sbjct  419  GWTAMEQAFHATLKKKPKQPEPS--PPLPALTKGQKLTAGGASIKEGATSPPAHFTEDTL  476

Query  480  LAAMETAGNKEFD--EDTEKKGLGTPATRAGIIEKLVYSQYATRKGKQIIPTDDGKVLVE  537
            L+AME A+ KEF   ED E KGLGTPATRAG+IEKLV S +  RK KQ++PT+ G  L+ 
Sbjct  477  LSAMEHASAKEFAKLEDVEHKGLGTPATRAGVIEKLVRSGFVERKKKQLFPTEKGTELIK  536

Query  538  ILPDFLKSASMTAEWENQLLLMEHGEIAPEQFMTGIKNMLTMMLNGCDAIS-EEETRRFQ  596
            ++PD LKS  +TAEWE++L  +E+GE++PE+FM+GI  MLT ++++ ++++    +    
Sbjct  537  VMPDTLKSVKLTAEWEERLGAVERGELSPEDFMAGITAMLTELVKSYQGVTVASAALSAS  596

Query  597  TRESIGTCPVCGSLVYESKTNFYC----SNHDCHFALWKDNRYLQSMEKNMDKKMAAELL  652
             R  IG CP CG  V E+K +F+C    +   C+FALWK++R++ S +K++ +K AA LL
Sbjct  597  GRTVIGICPRCGKNVVEGKKSFFCEGWNAAPACDFALWKNDRFFTSKHKELTRKAAAALL  656

Query  653  KSGCVHVKDLYSRKKNMYFEADLHMDADE  681
            K G V + +L+S KK + ++A + M+   
Sbjct  657  KKGRVAMTGLFSEKKGVLYDAIVVMEDTG  685

30) FPR_01100 in NC_021020


> NC_004668_R1|30|G30|29376814|NP_815968.1|Enterococcus_faecalis_V583|-|30310..32427|topB-2|EF2312|DNA 
topoisomerase III
Length=705

 Score =  500 bits (1886),  Expect = 9e-143, Method: Compositional matrix adjust.
 Identities = 284/575 (50%), Positives = 402/575 (70%), Gaps = 20/575 (3%)

Query  1    MEDAAIREGFANLRPDSDYDALYQSALCRAKADWLVGINATRLFSVLYH-KTLTVGRVQT  59
            ME+AAI+ GF NL  + +YD LY +ALCRAKADWL+GIN+TRLF+ LY+ K+L VGRVQT
Sbjct  133  MEEAAIQKGFDNLLDGKNYDNLYAAALCRAKADWLIGINGTRLFTTLYQGKSLNVGRVQT  192

Query  60   PTLKMLVDRDAKILRFQKEKYYTVGIQSGSLKAGSGRIADAETANSLKEKCTGTTTVCTS  119
            PTL +L +R+A I  FQKEK+YTV ++  +++A+S R+A    A  L+  C G  +   +
Sbjct  193  PTLALLAEREAAISGFQKEKFYTVELELEGFRAASERFASKTDAGRLRTGCVGKPATVQT  252

Query  120  VKREKKTEQPPKLYDLTTLQREVNRLFGFTAKQTLDYAQQLYEKKLLTYPRTDSQYLTED  179
            V +  KTE+PPKLYDLTTLQRE NRLF++TA+QTLDY Q LYEK+L TYPRTDS+YLTED
Sbjct  253  VSQKEKTERPPKLYDLTTLQREANRLFDYTAQQTLDYLQALYEKRLATYPRTDSRYLTED  312

Query  180  MGQTVRHLVSDLLGLLPFAQRLVLTPDVSRVLNSNKVSDHHAIIPTAEFAKQGFTGLAES  239
            M+  +  L   + + LPFA  L L  + ++V++++KV+DHHAI+PT+E AK ++++L+ +
Sbjct  313  MAAGLPALCQSVAAALPFAADLSLPVNAAQVIDNSKVTDHHAILPTTEAAKTDLSALPSG  372

Query  240  ECKLMNLVCSKLLCAVAIPHEYETVTAVFSCAGNEFTAKGKTVLVPGWKEIDQRFRSTLK  299
            E +++ LV ++LLCAV+ PH Y   +  + C+G  F+AKGKT   +GW  ++Q F++TLK
Sbjct  373  EKNILFLVAARLLCAVGEPHTYAETAVTLECGGAVFSAKGKTETAAGWTAMEQAFHATLK  432

Query  300  ADTEE-EVLNTLPELAEGQSFSV-TANVSEHFTSPPKAYTEDTLLSAMEWAGAEDMPEDK  357
                + E    LP L+ GQ ++   A++ E  TSPP  +TEDTLLSAME A+A + +   
Sbjct  433  KKPKQPEPSPPLPALTKGQKLTAGGASIKEGATSPPAHFTEDTLLSAMEHASAKEFAK--  490

Query  358  VNCSAGAREGGLGQAERKGLGTPATRAAILEKLVQIGFVQRKGKQLVPTKDGINLAVVLP  417
                       L + E+KGLGTPATRA+++EKLV+ GFV+RK KQL PT  G +L  V+P
Sbjct  491  -----------LEDVEHKGLGTPATRAGVIEKLVRSGFVERKKKQLFPTEKGTELIKVMP  539

Query  418  ESLTSPALTAEWENRLTEIAKGNADPDEFMAEIEAQVHQLVKTYSCISADKQNLFQSERV  477
            ++L S  LTAEWE+RL  + +G+  P++FMA I A + +LVK+Y  ++     L  S R 
Sbjct  540  DTLKSVKLTAEWEERLGAVERGELSPEDFMAGITAMLTELVKSYQGVTVASAALSASGRT  599

Query  478  IIGKCPRCGENVYDGKKNFYCGNR----GCQFVMWKNDRFFEQRKKAFTPKIAAALLKNG  533
            +IG CPRCG NV +GKK+F+C  +    +C+F +WKNDRFF  + K +T K AAALLK+G
Sbjct  600  VIGICPRCGKNVVEGKKSFFCEGWNAAPACDFALWKNDRFFTSKHKELTRKAAAALLKKG  659

Query  534  KAKVKGLYSEKTGKTYDATVLLADTGGKYVNYRVE  568
            +  + GL+SEK G  YDA V++ DTG K+V +++E
Sbjct  660  RVAMTGLFSEKKGVLYDAIVVMEDTGEKFVRFKLE  694

31) CD630_18590 in NC_009089


> NC_004668_R1|30|G30|29376814|NP_815968.1|Enterococcus_faecalis_V583|-|30310..32427|topB-2|EF2312|DNA 
topoisomerase III
Length=705

 Score =  454 bits (1712),  Expect = 6e-129, Method: Compositional matrix adjust.
 Identities = 270/583 (47%), Positives = 402/583 (69%), Gaps = 17/583 (2%)

Query  1    MKLVIAEKPSVAISIAKVIGATKKKDGYYEGNGYKVSWCVGHLIQMANPESYDEKYAKWN  60
            M+LVIAEKPSV+++++KV+GA  + DGY EG G  VSWC+GHL+++A +++YD +Y+KWN
Sbjct  1    MQLVIAEKPSVGMALSKVLGAKSRGDGYMEGGGWLVSWCIGHLVELAPADAYDPRYSKWN  60

Query  61   MADLPIIPREYKYEIAKSTKKQFTILKKLMNDKEIDIVINACDAGREGEAIFRLVYNQAN  120
             ADLPI+P+  ++++   TKKQF +LK L++  ++  +I A DAGREGE IFRL Y+   
Sbjct  61   YADLPILPKPWQFQVLPDTKKQFEVLKTLIHRADVTALICATDAGREGELIFRLTYHLCG  120

Query  121  CKKKMKRLWISSMEDSAIKEGFDNLKDGSFYDNLFESAQARAIADWLVGMNLSRLYSCLY  180
            C K +KRLWISSME++AI+ GFDNL DG  YDNL+ +A  RA ADWL+G+N +RL++ LY
Sbjct  121  CTKPVKRLWISSMEEAAIQKGFDNLLDGKNYDNLYAAALCRAKADWLIGINGTRLFTTLY  180

Query  181  K-QNYSVGRVQTPTLAMIVKRDDEIANFKKEKYFTVELDLDGFSLSTDRIDDKTVTEQL-  238
            + ++ +VGRVQTPTLA++  R+  I+ F+KEK++TVEL+L+GF  +++R+  KT + +L 
Sbjct  181  QGKSLNVGRVQTPTLALLAEREAAISGFQKEKFYTVELELEGFRAASERFASKTDAGRLR  240

Query  239  INLLGNSIEITDVIQKEKITKPELPFDLTTLQRECNKYFNYSAKQTLDYTQSLYEKKLIT  298
               +G++  +  V QKEK  +P   +DLTTLQRE N+ F+Y+A+QTLDY Q+LYEK+L T
Sbjct  241  TGCVGKPATVQTVSQKEKTERPPKLYDLTTLQREANRLFDYTAQQTLDYLQALYEKRLAT  300

Query  299  YPRTDSRYLTEDM---ITSTINNIVGKHDFDTG-----RIKMVFNSKRVTDHHAIIPTAS  350
            YPRTDSRYLTEDM   + +  +++ +   F ++         V+++ +VTDHHAI+PT+ 
Sbjct  301  YPRTDSRYLTEDMAAGLPALCQSVAAALPFAADLSLPVNAAQVIDNSKVTDHHAILPTTE  360

Query  351  SMNEDLASLPESELKVYELVLNKLHASVGYPLIENTTKIVAVFDGFEFTSSGK-------  403
            + + DL++LP +E ++  LV  +L  +VG P     T +    +G  F++ GK       
Sbjct  361  AAKTDLSALPSGEKNILFLVAARLLCAVGEPHTYAETAVTLECGGAVFSAKGKTETAAGW  420

Query  404  VIVDEGFTkylkkyikkkNEDTVFPDLKIGDSLDIKEKEIKENYTSPAKHFTEDTLLKDM  463
              ++++F   LKK  K+ +    +P L  G+ L      IKE  TSP+ HFTEDTLL  M
Sbjct  421  TAMEQAFHATLKKKPKQPEPSPPLPALTKGQKLTAGGASIKEGATSPPAHFTEDTLLSAM  480

Query  464  ELAGNDALEKGVEVERKGLGTPATRAGIIENLIFKGFVERDKKNLIATHKGISLVTIVSD  523
            E A+   + K  +VE+KGLGTPATRAG+IE+L+  GFVER KK+L++T+KG  L+ +++D
Sbjct  481  EHASAKEFAKLEDVEHKGLGTPATRAGVIEKLVRSGFVERKKKQLFPTEKGTELIKVMPD  540

Query  524  TFKSAGTTAKWEMELSDIAQGKASKENFLKAIENEIKELVSTY  566
            T+KS   TA WE  L+ + +G  S E+F+ +I   + ELV +Y
Sbjct  541  TLKSVKLTAEWEERLGAVERGELSPEDFMAGITAMLTELVKSY  583

32) SANR_1304 in NC_022239


> NC_004668_R1|30|G30|29376814|NP_815968.1|Enterococcus_faecalis_V583|-|30310..32427|topB-2|EF2312|DNA 
topoisomerase III
Length=705

 Score =  454 bits (1712),  Expect = 6e-129, Method: Compositional matrix adjust.
 Identities = 271/584 (47%), Positives = 400/584 (69%), Gaps = 17/584 (2%)

Query  4    KLVIAEKPSVALSISKIIGANGKKDGYYEGNGYRVSWCVGHLIQMANPDSYDEKYAKWNI  63
            +LVIAEKPSV++++SK++GA+++ DGY EG G  VSWC+GHL+++A +D+YD +Y+KWN 
Sbjct  2    QLVIAEKPSVGMALSKVLGAKSRGDGYMEGGGWLVSWCIGHLVELAPADAYDPRYSKWNY  61

Query  64   EDLPIIPSEYKYEVAKATKKQFTILKKLMNDKDIDSVINACDAGREGESIFRLVYNEAKC  123
             DLPI+P   +++V   TKKQF +LK L++  D+ ++I A DAGREGE IFRL Y+   C
Sbjct  62   ADLPILPKPWQFQVLPDTKKQFEVLKTLIHRADVTALICATDAGREGELIFRLTYHLCGC  121

Query  124  KKKMQRLWISSMEDSAIKEGFENLKDGKDYDNLFESALTRAIADWLVGMNISRLYSCLYK  183
             K ++RLWISSME++AI+ GF+NL DGK+YDNL+ +AL RA ADWL+G+N +RL++ LY+
Sbjct  122  TKPVKRLWISSMEEAAIQKGFDNLLDGKNYDNLYAAALCRAKADWLIGINGTRLFTTLYQ  181

Query  184  -QNYSVGRVQTPTLAMIVKRDDEIANFKKEKYYTVELSLDGFNLLTDRIDDKTAAEQL-F  241
             ++ +VGRVQTPTLA++  R+  I+ F+KEK+YTVEL L+GF   ++R+  KT A +L  
Sbjct  182  GKSLNVGRVQTPTLALLAEREAAISGFQKEKFYTVELELEGFRAASERFASKTDAGRLRT  241

Query  242  NLVGEKIEITNVIQKEKVTKPDLPFDLTTLQRECNKYFGYSAKQTLDYAQSLYEKKLITY  301
              VG    +  V QKEK  +P   +DLTTLQRE N+ F+Y+A+QTLDY Q+LYEK+L TY
Sbjct  242  GCVGKPATVQTVSQKEKTERPPKLYDLTTLQREANRLFDYTAQQTLDYLQALYEKRLATY  301

Query  302  PRTDSRCLTEDM---ITSTINNILGKNDFDTR-----RIKTVFNSKKVTDHHAIIPTISS  353
            PRTDSR LTEDM   + +  +++ +   F +          V+++ KVTDHHAI+PT  +
Sbjct  302  PRTDSRYLTEDMAAGLPALCQSVAAALPFAADLSLPVNAAQVIDNSKVTDHHAILPTTEA  361

Query  354  LKEDVSELPLSEANVYFLISDKFHASVGYPLVENTTKIVAEFDDFEFTSTGK-------V  406
             K D+S LP +E N+ FL++ ++  +VG P     T +  E ++  F++ GK        
Sbjct  362  AKTDLSALPSGEKNILFLVAARLLCAVGEPHTYAETAVTLECGGAVFSAKGKTETAAGWT  421

Query  407  IKDEGFTKYLKEYKIKNSDDVVLPMINTGDVLEVKDKEIREKYTTPPKHFTKGTLLKAME  466
              +++F   LK    +      LP +  G+ L   +  I+E  T+PP HFT +TLL AME
Sbjct  422  AMEQAFHATLKKKPKQPEPSPPLPALTKGQKLTAGGASIKEGATSPPAHFTEDTLLSAME  481

Query  467  IAGSEALEKGVEVERKGLGTPATRAGIIENLIYKGFIERDKKNLIATRKGKSLIEIVADT  526
             A++  + K  +VE+KGLGTPATRAG+IE+L+  GF+ER KK+L++T KG  LI +++DT
Sbjct  482  HASAKEFAKLEDVEHKGLGTPATRAGVIEKLVRSGFVERKKKQLFPTEKGTELIKVMPDT  541

Query  527  FKSAEMTAQWEMRLSDIAQGKSSKEEFLDSIEAEIKNAVAKYKE  570
            +KS  +TA+WE RL+ + +G  S E+F+ +I A + + V  Y+ 
Sbjct  542  LKSVKLTAEWEERLGAVERGELSPEDFMAGITAMLTELVKSYQG  585

33) CDR20291_1793 in NC_013316


> NC_004668_R1|30|G30|29376814|NP_815968.1|Enterococcus_faecalis_V583|-|30310..32427|topB-2|EF2312|DNA 
topoisomerase III
Length=705

 Score =  453 bits (1705),  Expect = 2e-128, Method: Compositional matrix adjust.
 Identities = 270/584 (47%), Positives = 398/584 (69%), Gaps = 17/584 (2%)

Query  1    MKLVIAEKPSVAISIAKVIGANKKKDGYYEGNGYRVSWCVGHLIQMANPDAYDEKYAKWN  60
            M+LVIAEKPSV+++++KV+GA+ + DGY EG G  VSWC+GHL+++A +DAYD +Y+KWN
Sbjct  1    MQLVIAEKPSVGMALSKVLGAKSRGDGYMEGGGWLVSWCIGHLVELAPADAYDPRYSKWN  60

Query  61   MADLPIIPSDYKYEVAKATKKQFNILKKLMNDKEVDTVINACDAGREGESIFRLVYNQVN  120
             ADLPI+P   +++V   TKKQF++LK L++  +V ++I A DAGREGE IFRL Y+   
Sbjct  61   YADLPILPKPWQFQVLPDTKKQFEVLKTLIHRADVTALICATDAGREGELIFRLTYHLCG  120

Query  121  CKKKMKRLWISSMEDSAIKEGFDNLTDGKDYDNLFESAQARAIADWLVGMNISRLYSCLY  180
            C K +KRLWISSME++AI+ GFDNL DGK+YDNL+ +A  RA ADWL+G+N +RL++ LY
Sbjct  121  CTKPVKRLWISSMEEAAIQKGFDNLLDGKNYDNLYAAALCRAKADWLIGINGTRLFTTLY  180

Query  181  Q-QNYSVGRVQTPTLAMIVKRDDEIANYQKEKYYTVELSMNGFTLSTDRIDDEVAAEQL-  238
            Q ++ +VGRVQTPTLA++  R+  I+ +QKEK+YTVEL ++GF  +++R+     A +L 
Sbjct  181  QGKSLNVGRVQTPTLALLAEREAAISGFQKEKFYTVELELEGFRAASERFASKTDAGRLR  240

Query  239  ISLVGDKIEITDVIQKEKITKPDLPFDLTTLQRECNKYFGYSAKQTLDYTQSLYEKKLIT  298
             + VG    +  V QKEK  +P   +DLTTLQRE N+ F+Y+A+QTLDY Q+LYEK+L T
Sbjct  241  TGCVGKPATVQTVSQKEKTERPPKLYDLTTLQREANRLFDYTAQQTLDYLQALYEKRLAT  300

Query  299  YPRTDSRCLTEDM---IVSTVNNILGKNDFDTE-----RIKVVFNSKKVTDHHAIIPTIS  350
            YPRTDSR LTEDM   + +  +++ +   F ++         V+++ KVTDHHAI+PT  
Sbjct  301  YPRTDSRYLTEDMAAGLPALCQSVAAALPFAADLSLPVNAAQVIDNSKVTDHHAILPTTE  360

Query  351  SVKEDVSELPLSEAKVYFLISDKFHASVGYPLIENTTKIVASFDGFEFTSSGK-------  403
            + K D+S LP +E ++ FL++ ++  +VG P     T +    +G  F++ GK       
Sbjct  361  AAKTDLSALPSGEKNILFLVAARLLCAVGEPHTYAETAVTLECGGAVFSAKGKTETAAGW  420

Query  404  VIKDEGFskylkeykskkseDAVLPDVSVGDVLSVENKEVKEKFTQPPKHFTEDTLLKSM  463
               +++F   LK    +    + LP ++ G+ L+     +KE  T PP HFTEDTLL +M
Sbjct  421  TAMEQAFHATLKKKPKQPEPSPPLPALTKGQKLTAGGASIKEGATSPPAHFTEDTLLSAM  480

Query  464  EIAGNDALEKGVEVERKGLGTPATRAGIIENLIFKRFVERDKKNLIATHKGISLVTIVAD  523
            E A+   + K  +VE+KGLGTPATRAG+IE+L+   FVER KK+L++T+KG  L+ +++D
Sbjct  481  EHASAKEFAKLEDVEHKGLGTPATRAGVIEKLVRSGFVERKKKQLFPTEKGTELIKVMPD  540

Query  524  TFKSAETTAKWEMELSDIAQGKSSKKEFLDAIENEIKEAVLTYR  567
            T+KS   TA WE  L+ + +G  S  +F+ +I   + E V +Y+
Sbjct  541  TLKSVKLTAEWEERLGAVERGELSPEDFMAGITAMLTELVKSYQ  584

34) SZO_12820 in NC_012470


> NC_004668_R1|30|G30|29376814|NP_815968.1|Enterococcus_faecalis_V583|-|30310..32427|topB-2|EF2312|DNA 
topoisomerase III
Length=705

 Score =  451 bits (1700),  Expect = 5e-128, Method: Compositional matrix adjust.
 Identities = 270/584 (47%), Positives = 399/584 (69%), Gaps = 19/584 (3%)

Query  1    MKLVIAEKPSVAISIAKVIGANKKKDGYYEGNGYRVSWCVGHLIQMANPDVYDEKYAKWN  60
            M+LVIAEKPSV+++++KV+GA+ + DGY EG G  VSWC+GHL+++A +D YD +Y+KWN
Sbjct  1    MQLVIAEKPSVGMALSKVLGAKSRGDGYMEGGGWLVSWCIGHLVELAPADAYDPRYSKWN  60

Query  61   MADLPIIPKEYKYEVAKSTKKQFAILKKLLNDKEIDTVINACDAGREGESIFRLVYNQAN  120
             ADLPI+PK  +++V   TKKQF +LK L++  ++ ++I A DAGREGE IFRL Y+   
Sbjct  61   YADLPILPKPWQFQVLPDTKKQFEVLKTLIHRADVTALICATDAGREGELIFRLTYHLCG  120

Query  121  CKKKMKRLWISSMEDSAIKEGFDNIKDGKDYDNLFESAQARAIADWLVGMNISRLYSCLY  180
            C K +KRLWISSME++AI+ GFDN+ DGK+YDNL+ +A  RA ADWL+G+N +RL++ LY
Sbjct  121  CTKPVKRLWISSMEEAAIQKGFDNLLDGKNYDNLYAAALCRAKADWLIGINGTRLFTTLY  180

Query  181  K-QNYSVGRVQTPTLAMIVKRDDEIANFKKEKYYTVELSMNGFTLSTDRIDDEIAAEQL-  238
            + ++ +VGRVQTPTLA++  R+  I+ F+KEK+YTVEL ++GF  +++R+     A +L 
Sbjct  181  QGKSLNVGRVQTPTLALLAEREAAISGFQKEKFYTVELELEGFRAASERFASKTDAGRLR  240

Query  239  LNLVGDKIEITDVIQKGKITKPDLPFDLTTLQRECNKYFGYSAKQTLDYAQSLYEKKLIT  298
               VG    +  V QK K  +P   +DLTTLQRE N+ F+Y+A+QTLDY Q+LYEK+L T
Sbjct  241  TGCVGKPATVQTVSQKEKTERPPKLYDLTTLQREANRLFDYTAQQTLDYLQALYEKRLAT  300

Query  299  YPRSDSRCLTEDM---IVNIVNNILGKNDFDTE-----RIKAVFNSKKVTDHHAIIPTVS  350
            YPR+DSR LTEDM   +  + +++ +   F ++         V+++ KVTDHHAI+PT  
Sbjct  301  YPRTDSRYLTEDMAAGLPALCQSVAAALPFAADLSLPVNAAQVIDNSKVTDHHAILPTTE  360

Query  351  SLSEDLSGIPEGEAKVYRLISDKFHASVGYPLIENTTKIVAVSDGFEFTSTGK-------  403
            +   DLS++P GE ++  L++ ++  +VG P     T +    +G  F++ GK       
Sbjct  361  AAKTDLSALPSGEKNILFLVAARLLCAVGEPHTYAETAVTLECGGAVFSAKGKTETAAGW  420

Query  404  VIKDEGFSKYLKEYKSKQSE-DAVMPDISVGDVLSIENKEIKEKFTQPPKHFTEDTLLKS  462
               +++F   LK  K+KQ+E  + +P ++ G+ L+     IKE  T PP HFTEDTLL +
Sbjct  421  TAMEQAFHATLKK-KPKQPEPSPPLPALTKGQKLTAGGASIKEGATSPPAHFTEDTLLSA  479

Query  463  MEIAGNDALEKGVEVERKGLGTPATRAGIIENLIFKGFVERDKKNLIATHKGISLVTIVT  522
            ME A+   + K  +VE+KGLGTPATRAG+IE+L+  GFVER KK+L++T+KG  L+ ++ 
Sbjct  480  MEHASAKEFAKLEDVEHKGLGTPATRAGVIEKLVRSGFVERKKKQLFPTEKGTELIKVMP  539

Query  523  DTFKSAETTAKWEMELSDIAQGKSSKEEFLKDIENEIKEAVLTY  566
            DT+KS   TA WE  L+ + +G  S E+F+ +I   + E V +Y
Sbjct  540  DTLKSVKLTAEWEERLGAVERGELSPEDFMAGITAMLTELVKSY  583

35) CD630_04210 in NC_009089


> NC_004668_R1|30|G30|29376814|NP_815968.1|Enterococcus_faecalis_V583|-|30310..32427|topB-2|EF2312|DNA 
topoisomerase III
Length=705

 Score =  451 bits (1698),  Expect = 7e-128, Method: Compositional matrix adjust.
 Identities = 268/584 (46%), Positives = 396/584 (68%), Gaps = 17/584 (2%)

Query  1    MKLVIAEKPSVAISIAKVIGVNKKKDGYYEGNGYRVSWCVGHLIQMANPDAYDEKYAKWN  60
            M+LVIAEKPSV+++++KV+G + + DGY EG G  VSWC+GHL+++A +DAYD +Y+KWN
Sbjct  1    MQLVIAEKPSVGMALSKVLGAKSRGDGYMEGGGWLVSWCIGHLVELAPADAYDPRYSKWN  60

Query  61   MADLPIIPSAYKYEVAKATKKQFNILKKLMNDKEIDTVINACDAGREGESIFRLVYNEAK  120
             ADLPI+P + +++V   TKKQF++LK L++  ++ ++I A DAGREGE IFRL Y+   
Sbjct  61   YADLPILPKPWQFQVLPDTKKQFEVLKTLIHRADVTALICATDAGREGELIFRLTYHLCG  120

Query  121  CKKKMKRLWISSMEDSAIKEGFDNLKDGKGYDNLFESAQARAIADWLVGMNISRLYSCLY  180
            C K +KRLWISSME++AI+ GFDNL DGK YDNL+ +A  RA ADWL+G+N +RL++ LY
Sbjct  121  CTKPVKRLWISSMEEAAIQKGFDNLLDGKNYDNLYAAALCRAKADWLIGINGTRLFTTLY  180

Query  181  K-QNYSVGRVQTPTLAMIVKRDDEIANFKKEKYYTVELSMNGFTLSTDRIDDEVAAEQL-  238
            + ++ +VGRVQTPTLA++  R+  I+ F+KEK+YTVEL ++GF  +++R+     A +L 
Sbjct  181  QGKSLNVGRVQTPTLALLAEREAAISGFQKEKFYTVELELEGFRAASERFASKTDAGRLR  240

Query  239  INLVGDKIEITDVIQKEKITNPDLPFDLTTLQRECNKYFGYSAKQTLDYAQSLYEKKLIT  298
               VG    +  V QKEK   P   +DLTTLQRE N+ F+Y+A+QTLDY Q+LYEK+L T
Sbjct  241  TGCVGKPATVQTVSQKEKTERPPKLYDLTTLQREANRLFDYTAQQTLDYLQALYEKRLAT  300

Query  299  YPRTDSRCLTEDM---ITSTINNILGKNDFDTG-----RIKTVFNSKKVTDHHAIIPTIS  350
            YPRTDSR LTEDM   + +  +++ +   F ++         V+++ KVTDHHAI+PT  
Sbjct  301  YPRTDSRYLTEDMAAGLPALCQSVAAALPFAADLSLPVNAAQVIDNSKVTDHHAILPTTE  360

Query  351  SLKEDVSKLPLSEAKVYFLISDKFHASVGYPLIENTTKIVASFDGFEFTSSGK-------  403
            + K D+S LP +E ++ FL++ ++  +VG P     T +    +G  F++ GK       
Sbjct  361  AAKTDLSALPSGEKNILFLVAARLLCAVGEPHTYAETAVTLECGGAVFSAKGKTETAAGW  420

Query  404  VIKDEGFSKYLKEYKSKKNEDAVLPNVSVGDVLSIENKEIKEKFTKPPKHFTEDTLLKSM  463
               +++F   LK    + +  + LP ++ G+ L+     IKE  T PP HFTEDTLL +M
Sbjct  421  TAMEQAFHATLKKKPKQPEPSPPLPALTKGQKLTAGGASIKEGATSPPAHFTEDTLLSAM  480

Query  464  EIAGNDALEKGVEVERKGLGTPATRAGIIENLIYKGFVERDKKNLIATHKGISLVTIVAD  523
            E A+   + K  +VE+KGLGTPATRAG+IE+L+  GFVER KK+L++T+KG  L+ +++D
Sbjct  481  EHASAKEFAKLEDVEHKGLGTPATRAGVIEKLVRSGFVERKKKQLFPTEKGTELIKVMPD  540

Query  524  NFKSAETTAKWEMELSDIAQGKSSKKEFLDAIENEIKEAVLTYR  567
             +KS   TA WE  L+ + +G  S  +F+ +I   + E V +Y+
Sbjct  541  TLKSVKLTAEWEERLGAVERGELSPEDFMAGITAMLTELVKSYQ  584

36) topA in NC_018712


> NC_004668_R1|30|G30|29376814|NP_815968.1|Enterococcus_faecalis_V583|-|30310..32427|topB-2|EF2312|DNA 
topoisomerase III
Length=705

 Score =  446 bits (1680),  Expect = 2e-126, Method: Compositional matrix adjust.
 Identities = 267/583 (46%), Positives = 397/583 (69%), Gaps = 17/583 (2%)

Query  1    MNLVIAEKPSVAISIAKVIGATKKKDGYYEGNGYKVSWCVGHLIKMANPESYDEKYAKWN  60
            M+LVIAEKPSV+++++KV+GA  + DGY EG G  VSWC+GHL+ +A +++YD +Y+KWN
Sbjct  1    MQLVIAEKPSVGMALSKVLGAKSRGDGYMEGGGWLVSWCIGHLVELAPADAYDPRYSKWN  60

Query  61   MADLPIIPKEYKYEIAKSTKKQFTILKKLMNDKDIDIVINACDAGREGEAIFRLVYNQAN  120
             ADLPI+PK  ++++   TKKQF +LK L++  D+  +I A DAGREGE IFRL Y+   
Sbjct  61   YADLPILPKPWQFQVLPDTKKQFEVLKTLIHRADVTALICATDAGREGELIFRLTYHLCG  120

Query  121  CKKRMKRLWISSMEDSAIKEGFDNLKDGSSYDNLFESAQARAIADWLVGMNLSRLYSCLY  180
            C K +KRLWISSME++AI+ GFDNL DG +YDNL+ +A  RA ADWL+G+N +RL++ LY
Sbjct  121  CTKPVKRLWISSMEEAAIQKGFDNLLDGKNYDNLYAAALCRAKADWLIGINGTRLFTTLY  180

Query  181  K-QNYSVGRVQTPTLAMIVKRDDEIANFKKEKYFTVELSLNGFTLSTDRIDDEITAEQL-  238
            + ++ +VGRVQTPTLA++  R+  I+ F+KEK++TVEL L+GF  +++R+     A +L 
Sbjct  181  QGKSLNVGRVQTPTLALLAEREAAISGFQKEKFYTVELELEGFRAASERFASKTDAGRLR  240

Query  239  LNLVGDKIEITDVIQKEKITKPELPFDLTTLQRECNKYFGYSAKQTLDYAQSLYEKKLIT  298
               VG    +  V QKEK  +P   +DLTTLQRE N+ F+Y+A+QTLDY Q+LYEK+L T
Sbjct  241  TGCVGKPATVQTVSQKEKTERPPKLYDLTTLQREANRLFDYTAQQTLDYLQALYEKRLAT  300

Query  299  YPRTDSRCLTEDM---IVSTVNNILGKNDFDTE-----RIKTVFNSKKVTDHHAIIPTAS  350
            YPRTDSR LTEDM   + +  +++ +   F ++         V+++ KVTDHHAI+PT+ 
Sbjct  301  YPRTDSRYLTEDMAAGLPALCQSVAAALPFAADLSLPVNAAQVIDNSKVTDHHAILPTTE  360

Query  351  SMNENLTSLPESELKVYELILNKLHASVGYPLIENTTKIVAEFDGFEFTSSGK-------  403
            + + +L++LP +E ++  L+  +L  +VG P     T +  E +G  F++ GK       
Sbjct  361  AAKTDLSALPSGEKNILFLVAARLLCAVGEPHTYAETAVTLECGGAVFSAKGKTETAAGW  420

Query  404  VIVDDGFTKYLNEYAKKKNEDTVLPDVKIGYSLDIKDKEIKEKYTQPAKHFTEDLLLKAM  463
              ++++F   L+  +K+ +    LP +  G  L   +  IKE  T P+ HFTED LL AM
Sbjct  421  TAMEQAFHATLKKKPKQPEPSPPLPALTKGQKLTAGGASIKEGATSPPAHFTEDTLLSAM  480

Query  464  ELAGNDALEKGVEVERKGLGTPATRAGIIENLIFKGFVERDKKNLIATHKGISLVTIVAD  523
            E A+   + K  +VE+KGLGTPATRAG+IE+L+  GFVER KK+L++T+KG  L+ +++D
Sbjct  481  EHASAKEFAKLEDVEHKGLGTPATRAGVIEKLVRSGFVERKKKQLFPTEKGTELIKVMPD  540

Query  524  TFKSAETTAKWEMELSDIAQGQSSKENFLEAIENEIKEVVSTY  566
            T+KS   TA WE  L+ + +G+ S E+F+ +I   + E+V +Y
Sbjct  541  TLKSVKLTAEWEERLGAVERGELSPEDFMAGITAMLTELVKSY  583

37) SANR_1853 in NC_022239


> NC_004668_R1|30|G30|29376814|NP_815968.1|Enterococcus_faecalis_V583|-|30310..32427|topB-2|EF2312|DNA 
topoisomerase III
Length=705

 Score =  445 bits (1676),  Expect = 4e-126, Method: Compositional matrix adjust.
 Identities = 260/569 (46%), Positives = 392/569 (69%), Gaps = 17/569 (2%)

Query  1    MKLVIAEKPSVAISIAKVIGANKKKDGYYEGNEYKVSWCVGHLIQMANPDSYDEKYAKWN  60
            M+LVIAEKPSV+++++KV+GA+ + DGY EG    VSWC+GHL+++A +D+YD +Y+KWN
Sbjct  1    MQLVIAEKPSVGMALSKVLGAKSRGDGYMEGGGWLVSWCIGHLVELAPADAYDPRYSKWN  60

Query  61   MADLPIIPREYKYEVAKATKKQFNILKKLMNDKEIDMVINACDAGREGEAIFRLVYNEAK  120
             ADLPI+P+  +++V   TKKQF++LK L++  ++  +I A DAGREGE IFRL Y+   
Sbjct  61   YADLPILPKPWQFQVLPDTKKQFEVLKTLIHRADVTALICATDAGREGELIFRLTYHLCG  120

Query  121  CKKKMKRLWISSMEDSAIKEGFDNLKDGKDYDNLFESSQARAIADWLVGMNISRLYSCLY  180
            C K +KRLWISSME++AI+ GFDNL DGK+YDNL+ ++  RA ADWL+G+N +RL++ LY
Sbjct  121  CTKPVKRLWISSMEEAAIQKGFDNLLDGKNYDNLYAAALCRAKADWLIGINGTRLFTTLY  180

Query  181  Q-QNYSVGRVQTPTLAMIVKRDDEIANFQQDKYYIVELSMNGFTLSTDRIDDEVTTEQL-  238
            Q ++ +VGRVQTPTLA++  R+  I+ FQ++K+Y VEL ++GF  +++R+     + +L 
Sbjct  181  QGKSLNVGRVQTPTLALLAEREAAISGFQKEKFYTVELELEGFRAASERFASKTDAGRLR  240

Query  239  INLVDDKIEITDIIQKEKITKPDLPFDLTTLQRECNKYFGYSAKQTLDYAQSLYEKKLIT  298
               V+    +  + QKEK  +P   +DLTTLQRE N+ F+Y+A+QTLDY Q+LYEK+L T
Sbjct  241  TGCVGKPATVQTVSQKEKTERPPKLYDLTTLQREANRLFDYTAQQTLDYLQALYEKRLAT  300

Query  299  YPRTDSRCLTEDM---IVSTVNNILGKNDFDTE-----RIKVVFNSKKVTDHHAIIPTIS  350
            YPRTDSR LTEDM   + +  +++ +   F ++         V+++ KVTDHHAI+PT  
Sbjct  301  YPRTDSRYLTEDMAAGLPALCQSVAAALPFAADLSLPVNAAQVIDNSKVTDHHAILPTTE  360

Query  351  SVKEDVSELPLSEAKVYFLISDKFHASVGYPLVESATKIVAEFDGFEFTSSGK-------  403
            + K D+S LP +E ++ FL++ ++  +VG P   + T +  E +G  F++ GK       
Sbjct  361  AAKTDLSALPSGEKNILFLVAARLLCAVGEPHTYAETAVTLECGGAVFSAKGKTETAAGW  420

Query  404  VIVDEGFTKCLKEYKAKKDENTELPDVSIGDVLSIENKEIKEKFTQPLKHFTEDTLLKAM  463
              ++++F   LK    + + +  LP ++ G+ L+     IKE  T P  HFTEDTLL AM
Sbjct  421  TAMEQAFHATLKKKPKQPEPSPPLPALTKGQKLTAGGASIKEGATSPPAHFTEDTLLSAM  480

Query  464  EIAGNDALEKGVEVERKGLGTPATRAGIIENLIFKGFVERDKKNLIATHKGISLVTIVAD  523
            E A+   + K  +VE+KGLGTPATRAG+IE+L+  GFVER KK+L++T+KG  L+ +++D
Sbjct  481  EHASAKEFAKLEDVEHKGLGTPATRAGVIEKLVRSGFVERKKKQLFPTEKGTELIKVMPD  540

Query  524  SFKSAETTAKWEMELSDIAKGKENKEDFL  552
            ++KS   TA WE  L+ + +G  + EDF+
Sbjct  541  TLKSVKLTAEWEERLGAVERGELSPEDFM  569

38) SANR_1345 in NC_022239


> NC_004668_R1|30|G30|29376814|NP_815968.1|Enterococcus_faecalis_V583|-|30310..32427|topB-2|EF2312|DNA 
topoisomerase III
Length=705

 Score =  444 bits (1674),  Expect = 5e-126, Method: Compositional matrix adjust.
 Identities = 267/583 (46%), Positives = 397/583 (69%), Gaps = 17/583 (2%)

Query  1    MKLVIAEKPSVAISIAKVIGATKKKDGYYEGNGYKVSWCVGHLIKMANPESYDEKYAKWN  60
            M+LVIAEKPSV+++++KV+GA  + DGY EG G  VSWC+GHL+ +A +++YD +Y+KWN
Sbjct  1    MQLVIAEKPSVGMALSKVLGAKSRGDGYMEGGGWLVSWCIGHLVELAPADAYDPRYSKWN  60

Query  61   MADLPIIPKEYKYEIAKSTKKQFTILKKLMNDKDIDIVINACDAGREGEAIFRLVYNQAN  120
             ADLPI+PK  ++++   TKKQF +LK L++  D+  +I A DAGREGE IFRL Y+   
Sbjct  61   YADLPILPKPWQFQVLPDTKKQFEVLKTLIHRADVTALICATDAGREGELIFRLTYHLCG  120

Query  121  CKKRMKRLWISSMEDSAIKEGFDNLKDGSSYDNLFESAQARAIADWLVGMNLSRLYSCLY  180
            C K +KRLWISSME++AI+ GFDNL DG +YDNL+ +A  RA ADWL+G+N +RL++ LY
Sbjct  121  CTKPVKRLWISSMEEAAIQKGFDNLLDGKNYDNLYAAALCRAKADWLIGINGTRLFTTLY  180

Query  181  K-QNYSVGRVQTPTLAMIVNRDDEIANFKKEKYNTVELSLNGFTLSTDRIDDEVAAEQL-  238
            + ++ +VGRVQTPTLA++ +R+  I+ F+KEK+ TVEL L+GF  +++R+     A +L 
Sbjct  181  QGKSLNVGRVQTPTLALLAEREAAISGFQKEKFYTVELELEGFRAASERFASKTDAGRLR  240

Query  239  INLVGDKIEITDVIQKEKITKPELPFDLTTLQRECNKYFGYSAKQTLDYAQSLYEKKLIT  298
               VG    +  V QKEK  +P   +DLTTLQRE N+ F+Y+A+QTLDY Q+LYEK+L T
Sbjct  241  TGCVGKPATVQTVSQKEKTERPPKLYDLTTLQREANRLFDYTAQQTLDYLQALYEKRLAT  300

Query  299  YPRTDSRCLTEDM---IVSTVNNILGKNDFDTE-----RIKTVFNSKKVTDHHAIIPTAS  350
            YPRTDSR LTEDM   + +  +++ +   F ++         V+++ KVTDHHAI+PT+ 
Sbjct  301  YPRTDSRYLTEDMAAGLPALCQSVAAALPFAADLSLPVNAAQVIDNSKVTDHHAILPTTE  360

Query  351  SMNENLTSLPESELKVYELILNKLHASVGYPLIENTTKIVAEFDGFEFTSSGK-------  403
            + + +L++LP +E ++  L+  +L  +VG P     T +  E +G  F++ GK       
Sbjct  361  AAKTDLSALPSGEKNILFLVAARLLCAVGEPHTYAETAVTLECGGAVFSAKGKTETAAGW  420

Query  404  VIVDDGFTKYLNEYAKKKNEDTVLPDVKIGYSLDIKDKEIKEKYTQPAKHFTEDLLLKAM  463
              ++++F   L+  +K+ +    LP +  G  L   +  IKE  T P+ HFTED LL AM
Sbjct  421  TAMEQAFHATLKKKPKQPEPSPPLPALTKGQKLTAGGASIKEGATSPPAHFTEDTLLSAM  480

Query  464  ELAGNDALEKGVEVERKGLGTPATRAGIIENLIFKGFVERDKKNLIATHKGISLVTIVAD  523
            E A+   + K  +VE+KGLGTPATRAG+IE+L+  GFVER KK+L++T+KG  L+ +++D
Sbjct  481  EHASAKEFAKLEDVEHKGLGTPATRAGVIEKLVRSGFVERKKKQLFPTEKGTELIKVMPD  540

Query  524  TFKSAETTAKWEMELSDIAQGQSSKENFLEAIENEIKEVVSTY  566
            T+KS   TA WE  L+ + +G+ S E+F+ +I   + E+V +Y
Sbjct  541  TLKSVKLTAEWEERLGAVERGELSPEDFMAGITAMLTELVKSY  583

39) SEQ_1256 in NC_012471


> NC_004668_R1|30|G30|29376814|NP_815968.1|Enterococcus_faecalis_V583|-|30310..32427|topB-2|EF2312|DNA 
topoisomerase III
Length=705

 Score =  443 bits (1670),  Expect = 1e-125, Method: Compositional matrix adjust.
 Identities = 262/582 (46%), Positives = 394/582 (68%), Gaps = 17/582 (2%)

Query  4    LVISEKPSVAISISKVLGATKKKDGYNEGNGYRVSWCVGHLIQMANPDAYDEKYAKWDMA  63
            LVI+EKPSV++++SKVLGA  + DGY EG G  VSWC+GHL+++A +DAYD +Y+KW+ A
Sbjct  3    LVIAEKPSVGMALSKVLGAKSRGDGYMEGGGWLVSWCIGHLVELAPADAYDPRYSKWNYA  62

Query  64   DLPIIPKDYKYEVAKATKKQFNILKKLMNDKEIDTVINACDAGREGESIFRLVYNQVNCK  123
            DLPI+PK  +++V   TKKQF++LK L++  ++ ++I A DAGREGE IFRL Y+   C 
Sbjct  63   DLPILPKPWQFQVLPDTKKQFEVLKTLIHRADVTALICATDAGREGELIFRLTYHLCGCT  122

Query  124  KKMKRLWISSMEDSAIKEGFDHLKDGKKYDNLFESAQARAIADWLVGMNISRLYSCLYN-  182
            K +KRLWISSME++AI+ GFD+L DGK+YDNL+ +A  RA ADWL+G+N +RL++ LY+ 
Sbjct  123  KPVKRLWISSMEEAAIQKGFDNLLDGKNYDNLYAAALCRAKADWLIGINGTRLFTTLYQG  182

Query  183  QNYSVGRVQTPTLAMIVKRDDEIANFKKEKYYTVELSMDGFILSTDRIDDKVAAEQL-IN  241
            ++ +VGRVQTPTLA++  R+  I+ F+KEK+YTVEL ++GF  +++R+  K  A +L   
Sbjct  183  KSLNVGRVQTPTLALLAEREAAISGFQKEKFYTVELELEGFRAASERFASKTDAGRLRTG  242

Query  242  LVGDKIEITDVIQNEKITKPDLPFDLTTLQRECNKYFGYSAKQTLDYAQSLYEKKLITYP  301
             VG    +  V Q+EK  +P   +DLTTLQRE N+ F+Y+A+QTLDY Q+LYEK+L TYP
Sbjct  243  CVGKPATVQTVSQKEKTERPPKLYDLTTLQREANRLFDYTAQQTLDYLQALYEKRLATYP  302

Query  302  RTDSRCLTEDM---ITSMINNILGQNDFDTG-----RIKVIFNSSKVTDHHAIIPTVSSM  353
            RTDSR LTEDM   + ++ +++ +   F ++         ++++SKVTDHHAI+PT  + 
Sbjct  303  RTDSRYLTEDMAAGLPALCQSVAAALPFAADLSLPVNAAQVIDNSKVTDHHAILPTTEAA  362

Query  354  SEDLLSIPESEAKVYGLIFNKLHASVGYPLIENTTKIVVTFDGFKFTSSGK-------VI  406
              DL ++P +E ++  L+  +L  +VG P     T + +  +G  F++ GK         
Sbjct  363  KTDLSALPSGEKNILFLVAARLLCAVGEPHTYAETAVTLECGGAVFSAKGKTETAAGWTA  422

Query  407  KDEGFTKYLKEYKTKKNEDIELPNVNIGDSLKIKDKEIKEKYTQPPKHFTENTLLKSMET  466
             +++F   LK    + +    LP +  G+ L   +  IKE  T PP HFTE+TLL +ME 
Sbjct  423  MEQAFHATLKKKPKQPEPSPPLPALTKGQKLTAGGASIKEGATSPPAHFTEDTLLSAMEH  482

Query  467  AGNDALKKGIEVERKGIGTPATRAGIIENLIYKGFIQRDKKNLVATHKGISLITIVADNF  526
            A+   + K  +VE+KG+GTPATRAG+IE+L+  GF++R KK+L +T+KG  LI +++D +
Sbjct  483  ASAKEFAKLEDVEHKGLGTPATRAGVIEKLVRSGFVERKKKQLFPTEKGTELIKVMPDTL  542

Query  527  KSAETTAKWEMELSDISQGKSSKEEFLRRVEAEIRNELSRYK  568
            KS   TA WE  L+ + +G  S E+F+  + A + + +  Y+
Sbjct  543  KSVKLTAEWEERLGAVERGELSPEDFMAGITAMLTELVKSYQ  584

40) SII_1009 in NC_022237


> NC_004668_R1|30|G30|29376814|NP_815968.1|Enterococcus_faecalis_V583|-|30310..32427|topB-2|EF2312|DNA 
topoisomerase III
Length=705

 Score =  443 bits (1670),  Expect = 1e-125, Method: Compositional matrix adjust.
 Identities = 265/583 (46%), Positives = 397/583 (69%), Gaps = 17/583 (2%)

Query  1    MKLVIAEKPSVAISIAKVIGANKKKDGYYEGNGYRVSWCVGHLIQMANPDAYDEKYAKWN  60
            M+LVIAEKPSV+++++KV+GA+ + DGY EG G  VSWC+GHL+++A +DAYD +Y+KWN
Sbjct  1    MQLVIAEKPSVGMALSKVLGAKSRGDGYMEGGGWLVSWCIGHLVELAPADAYDPRYSKWN  60

Query  61   MADLPIIPSDYKYEVSKSTKKQFNILKKLMNDKDIETVVNACDAGREGESIFRFVYNEAK  120
             ADLPI+P   +++V   TKKQF++LK L++  D+ +++ A DAGREGE IFR+ Y+   
Sbjct  61   YADLPILPKPWQFQVLPDTKKQFEVLKTLIHRADVTALICATDAGREGELIFRLTYHLCG  120

Query  121  CKNKMQRLWISSMEDSAIKEGFENLKDGKDYDNLFESAQARAIADWLVGMNISRLYSCLY  180
            C + ++RLWISSME++AI+ GF+NL DGK+YDNL+ +A  RA ADWL+G+N +RL++ LY
Sbjct  121  CTKPVKRLWISSMEEAAIQKGFDNLLDGKNYDNLYAAALCRAKADWLIGINGTRLFTTLY  180

Query  181  Q-QNYSVGRVQTPTLAMIVKRDDEIANFKKEKYYSVELSTNGFTLSTDRIDDEVTAEQL-  238
            Q ++ +VGRVQTPTLA++  R+  I+ F+KEK+Y+VEL  +GF  +++R+     A +L 
Sbjct  181  QGKSLNVGRVQTPTLALLAEREAAISGFQKEKFYTVELELEGFRAASERFASKTDAGRLR  240

Query  239  LNLVGDKIEITDVIQNEKITKPNLPFDLTTLQRECNKYFGYSAKQTLDYAQSLYEKKLIT  298
               VG    +  V Q+EK  +P   +DLTTLQRE N+ F+Y+A+QTLDY Q+LYEK+L T
Sbjct  241  TGCVGKPATVQTVSQKEKTERPPKLYDLTTLQREANRLFDYTAQQTLDYLQALYEKRLAT  300

Query  299  YPRTDSRCLTEDM---IVSTVNNILGKNDFDTE-----RIKVVFNSKKVTDHHAIIPTVS  350
            YPRTDSR LTEDM   + +  +++ +   F ++         V+++ KVTDHHAI+PT  
Sbjct  301  YPRTDSRYLTEDMAAGLPALCQSVAAALPFAADLSLPVNAAQVIDNSKVTDHHAILPTTE  360

Query  351  SLSEDLSNIPESEVKVYRLISNKLHASVGYPLVESTTKIVAEFDGFEFTSSGK-------  403
            +   DLS +P +E ++  L++ +L  +VG P   + T +  E +G  F++ GK       
Sbjct  361  AAKTDLSALPSGEKNILFLVAARLLCAVGEPHTYAETAVTLECGGAVFSAKGKTETAAGW  420

Query  404  VIKDEGFTKYLKEYKSKKNEDAEFPDVSVGDILSIENKEIKEKFTQPPKHFTEDTLLKSM  463
               +++F   LK    + +  + +P ++ G+ L+     IKE  T PP HFTEDTLL +M
Sbjct  421  TAMEQAFHATLKKKPKQPEPSPPLPALTKGQKLTAGGASIKEGATSPPAHFTEDTLLSAM  480

Query  464  EIAGNDALEKGVEVERKGLGTPATRAGIIENLIFKGFVERDKKNLIATHKGISLVTIVAD  523
            E A+   + K  +VE+KGLGTPATRAG+IE+L+  GFVER KK+L++T+KG  L+ +++D
Sbjct  481  EHASAKEFAKLEDVEHKGLGTPATRAGVIEKLVRSGFVERKKKQLFPTEKGTELIKVMPD  540

Query  524  NFKSAETTAKWEMELSDIAQGKSSKEEFLEAIENELKEAVLTY  566
             +KS   TA WE  L+ + +G  S E+F+ +I   L E V +Y
Sbjct  541  TLKSVKLTAEWEERLGAVERGELSPEDFMAGITAMLTELVKSY  583

41) SDSE_1343 in NC_019042


> NC_004668_R1|30|G30|29376814|NP_815968.1|Enterococcus_faecalis_V583|-|30310..32427|topB-2|EF2312|DNA 
topoisomerase III
Length=705

 Score =  442 bits (1664),  Expect = 3e-125, Method: Compositional matrix adjust.
 Identities = 266/583 (46%), Positives = 395/583 (68%), Gaps = 17/583 (2%)

Query  1    MKLVIAEKPSVAISITKVIGANKKKDGYYEGNGYRVSWCVGHLIQMANPDAYDEKYAKWN  60
            M+LVIAEKPSV+++++KV+GA+ + DGY EG G  VSWC+GHL+++A +DAYD +Y+KWN
Sbjct  1    MQLVIAEKPSVGMALSKVLGAKSRGDGYMEGGGWLVSWCIGHLVELAPADAYDPRYSKWN  60

Query  61   MADLPIILKDYKYEVAKSTKKQFNILKKLMNDKEVDTVINACDSGREGESIFRLVYNQAN  120
             ADLPI+ K  +++V   TKKQF++LK L++  +V ++I A D+GREGE IFRL Y+   
Sbjct  61   YADLPILPKPWQFQVLPDTKKQFEVLKTLIHRADVTALICATDAGREGELIFRLTYHLCG  120

Query  121  CKKKMKRLWISSMEDSAIKDGFDHLKDGEEYDNLFESAQARAIADWLVGMNISRLYSCLY  180
            C K +KRLWISSME++AI+ GFD+L DG +YDNL+ +A  RA ADWL+G+N +RL++ LY
Sbjct  121  CTKPVKRLWISSMEEAAIQKGFDNLLDGKNYDNLYAAALCRAKADWLIGINGTRLFTTLY  180

Query  181  K-QNYSVGRVQTPTLAMIVKRDDEIANFKKEKYYTVDLSTNGFTLSTDRIDDEIAAEQLL  239
            + ++ +VGRVQTPTLA++  R+  I+ F+KEK+YTV+L  +GF  +++R+     A +L 
Sbjct  181  QGKSLNVGRVQTPTLALLAEREAAISGFQKEKFYTVELELEGFRAASERFASKTDAGRLR  240

Query  240  TL-VGNKIEITDVIQKEKITKPDLPFDLTTLQRECNKYFGYSAKQTLDYAQSLYEKKLIT  298
            T  VG+   +  V QKEK  +P   +DLTTLQRE N+ F+Y+A+QTLDY Q+LYEK+L T
Sbjct  241  TGCVGKPATVQTVSQKEKTERPPKLYDLTTLQREANRLFDYTAQQTLDYLQALYEKRLAT  300

Query  299  YPRTDSRCLTEDM---IVSTVNNILGKNDFDTE-----RIKTVFNSKKVTDHHAIIPTVS  350
            YPRTDSR LTEDM   + +  +++ +   F ++         V+++ KVTDHHAI+PT  
Sbjct  301  YPRTDSRYLTEDMAAGLPALCQSVAAALPFAADLSLPVNAAQVIDNSKVTDHHAILPTTE  360

Query  351  SLSEDLSGIPEGEAKVYRLISDKFHASVGYPLIENTTKIVAVFDGFEFTSSGK-------  403
            +   DLS++P GE ++  L++ ++  +VG P     T +    +G  F++ GK       
Sbjct  361  AAKTDLSALPSGEKNILFLVAARLLCAVGEPHTYAETAVTLECGGAVFSAKGKTETAAGW  420

Query  404  VIKDEGFTkylkeykskkseDAVLPDVSVGDVLSIENKEIKEKYTQPPKHFTEDTLLKSM  463
               +++F   LK    +    + LP ++ G+ L+     IKE  T PP HFTEDTLL +M
Sbjct  421  TAMEQAFHATLKKKPKQPEPSPPLPALTKGQKLTAGGASIKEGATSPPAHFTEDTLLSAM  480

Query  464  EIAGNEALEKGVEVERKGLGTPATRAGIIENLIFKGFVERDKKNLIAMHKGISLVTIVAD  523
            E A+   + K  +VE+KGLGTPATRAG+IE+L+  GFVER KK+L++ +KG  L+ +++D
Sbjct  481  EHASAKEFAKLEDVEHKGLGTPATRAGVIEKLVRSGFVERKKKQLFPTEKGTELIKVMPD  540

Query  524  NFKSAETTAKWEMELSDIAQGKSSKEEFLEAIENEIKEAVSTY  566
             +KS   TA WE  L+ + +G  S E+F+ +I   + E V +Y
Sbjct  541  TLKSVKLTAEWEERLGAVERGELSPEDFMAGITAMLTELVKSY  583

42) SDE12394_07175 in NC_017567


> NC_004668_R1|30|G30|29376814|NP_815968.1|Enterococcus_faecalis_V583|-|30310..32427|topB-2|EF2312|DNA 
topoisomerase III
Length=705

 Score =  442 bits (1664),  Expect = 3e-125, Method: Compositional matrix adjust.
 Identities = 266/583 (46%), Positives = 395/583 (68%), Gaps = 17/583 (2%)

Query  1    MKLVIAEKPSVAISITKVIGANKKKDGYYEGNGYRVSWCVGHLIQMANPDAYDEKYAKWN  60
            M+LVIAEKPSV+++++KV+GA+ + DGY EG G  VSWC+GHL+++A +DAYD +Y+KWN
Sbjct  1    MQLVIAEKPSVGMALSKVLGAKSRGDGYMEGGGWLVSWCIGHLVELAPADAYDPRYSKWN  60

Query  61   MADLPIILKDYKYEVAKSTKKQFNILKKLMNDKEVDTVINACDSGREGESIFRLVYNQAN  120
             ADLPI+ K  +++V   TKKQF++LK L++  +V ++I A D+GREGE IFRL Y+   
Sbjct  61   YADLPILPKPWQFQVLPDTKKQFEVLKTLIHRADVTALICATDAGREGELIFRLTYHLCG  120

Query  121  CKKKMKRLWISSMEDSAIKDGFDHLKDGEEYDNLFESAQARAIADWLVGMNISRLYSCLY  180
            C K +KRLWISSME++AI+ GFD+L DG +YDNL+ +A  RA ADWL+G+N +RL++ LY
Sbjct  121  CTKPVKRLWISSMEEAAIQKGFDNLLDGKNYDNLYAAALCRAKADWLIGINGTRLFTTLY  180

Query  181  K-QNYSVGRVQTPTLAMIVKRDDEIANFKKEKYYTVDLSTNGFTLSTDRIDDEIAAEQLL  239
            + ++ +VGRVQTPTLA++  R+  I+ F+KEK+YTV+L  +GF  +++R+     A +L 
Sbjct  181  QGKSLNVGRVQTPTLALLAEREAAISGFQKEKFYTVELELEGFRAASERFASKTDAGRLR  240

Query  240  TL-VGNKIEITDVIQKEKITKPDLPFDLTTLQRECNKYFGYSAKQTLDYAQSLYEKKLIT  298
            T  VG+   +  V QKEK  +P   +DLTTLQRE N+ F+Y+A+QTLDY Q+LYEK+L T
Sbjct  241  TGCVGKPATVQTVSQKEKTERPPKLYDLTTLQREANRLFDYTAQQTLDYLQALYEKRLAT  300

Query  299  YPRTDSRCLTEDM---IVSTVNNILGKNDFDTE-----RIKTVFNSKKVTDHHAIIPTVS  350
            YPRTDSR LTEDM   + +  +++ +   F ++         V+++ KVTDHHAI+PT  
Sbjct  301  YPRTDSRYLTEDMAAGLPALCQSVAAALPFAADLSLPVNAAQVIDNSKVTDHHAILPTTE  360

Query  351  SLSEDLSGIPEGEAKVYRLISDKFHASVGYPLIENTTKIVAVFDGFEFTSSGK-------  403
            +   DLS++P GE ++  L++ ++  +VG P     T +    +G  F++ GK       
Sbjct  361  AAKTDLSALPSGEKNILFLVAARLLCAVGEPHTYAETAVTLECGGAVFSAKGKTETAAGW  420

Query  404  VIKDEGFTkylkeykskkseDAVLPDVSVGDVLSIENKEIKEKYTQPPKHFTEDTLLKSM  463
               +++F   LK    +    + LP ++ G+ L+     IKE  T PP HFTEDTLL +M
Sbjct  421  TAMEQAFHATLKKKPKQPEPSPPLPALTKGQKLTAGGASIKEGATSPPAHFTEDTLLSAM  480

Query  464  EIAGNEALEKGVEVERKGLGTPATRAGIIENLIFKGFVERDKKNLIAMHKGISLVTIVAD  523
            E A+   + K  +VE+KGLGTPATRAG+IE+L+  GFVER KK+L++ +KG  L+ +++D
Sbjct  481  EHASAKEFAKLEDVEHKGLGTPATRAGVIEKLVRSGFVERKKKQLFPTEKGTELIKVMPD  540

Query  524  NFKSAETTAKWEMELSDIAQGKSSKEEFLEAIENEIKEAVSTY  566
             +KS   TA WE  L+ + +G  S E+F+ +I   + E V +Y
Sbjct  541  TLKSVKLTAEWEERLGAVERGELSPEDFMAGITAMLTELVKSY  583

43) SIR_0986 in NC_022246


> NC_004668_R1|30|G30|29376814|NP_815968.1|Enterococcus_faecalis_V583|-|30310..32427|topB-2|EF2312|DNA 
topoisomerase III
Length=705

 Score =  437 bits (1646),  Expect = 1e-123, Method: Compositional matrix adjust.
 Identities = 260/561 (47%), Positives = 384/561 (69%), Gaps = 17/561 (3%)

Query  1    MKLVIAEKPSVAISIAKVIGANKKKDGYYEGNGYRVSWCVGHLIQMANPDAYDEKYTKWN  60
            M+LVIAEKPSV+++++KV+GA+ + DGY EG G  VSWC+GHL+++A +DAYD +Y+KWN
Sbjct  1    MQLVIAEKPSVGMALSKVLGAKSRGDGYMEGGGWLVSWCIGHLVELAPADAYDPRYSKWN  60

Query  61   ITDLPIVPKNYKYEIAKSTRKQFNILKKLMNDKEIDMVINACDAGREGESIFRLVYNEAK  120
             +DLPI+PK  ++++   T+KQF++LK L++  ++  +I A DAGREGE IFRL Y+   
Sbjct  61   YADLPILPKPWQFQVLPDTKKQFEVLKTLIHRADVTALICATDAGREGELIFRLTYHLCG  120

Query  121  CKKKMKRLWISSMEDSAIKEGFDNLKDGKDYDNLFESAQARAIADWLVGMNISRLYSCLY  180
            C K +KRLWISSME++AI+ GFDNL DGK+YDNL+ +A  RA ADWL+G+N +RL++ LY
Sbjct  121  CTKPVKRLWISSMEEAAIQKGFDNLLDGKNYDNLYAAALCRAKADWLIGINGTRLFTTLY  180

Query  181  Q-QNYSVGRVQTPTLAMIVKRDDEIANFKKEKYYAVELATNGFTLSTDRIDDEVAAEQL-  238
            Q ++ +VGRVQTPTLA++  R+  I+ F+KEK+Y+VEL  +GF  +++R+     A +L 
Sbjct  181  QGKSLNVGRVQTPTLALLAEREAAISGFQKEKFYTVELELEGFRAASERFASKTDAGRLR  240

Query  239  LNLVGDKIEITDIIQKEKITKPDLPFDLTTLQRECNKYFGYSAKQTLDYTQSLYEKKLIT  298
               VG    +  + QKEK  +P   +DLTTLQRE N+ F+Y+A+QTLDY Q+LYEK+L T
Sbjct  241  TGCVGKPATVQTVSQKEKTERPPKLYDLTTLQREANRLFDYTAQQTLDYLQALYEKRLAT  300

Query  299  YPRTDSRCLTEDM---IVSTVNNILGKNDFDTE-----RIKVVFNSKKVTDHHAIIPTIS  350
            YPRTDSR LTEDM   + +  +++ +   F ++         V+++ KVTDHHAI+PT  
Sbjct  301  YPRTDSRYLTEDMAAGLPALCQSVAAALPFAADLSLPVNAAQVIDNSKVTDHHAILPTTE  360

Query  351  SVKEDISELPLSEAKVYRLISNKLHASVGYPLIENTTKIVASFDGFEFTSSGK-------  403
            + K D+S LP +E ++  L++ +L  +VG P     T +    +G  F++ GK       
Sbjct  361  AAKTDLSALPSGEKNILFLVAARLLCAVGEPHTYAETAVTLECGGAVFSAKGKTETAAGW  420

Query  404  VIKDEGFSKYLKEYKSKKNEDIELPDVKVGDVISIDNKNIKEKFTQPPKHFTEDTLLKSM  463
               +++F   LK    + +    LP +  G+ ++ +  +IKE  T PP HFTEDTLL +M
Sbjct  421  TAMEQAFHATLKKKPKQPEPSPPLPALTKGQKLTAGGASIKEGATSPPAHFTEDTLLSAM  480

Query  464  EIAGNEALEKGVEVERKGLGTPATRAGIIENLIYKGFVERDKKNLIATHKGISLVTIVSD  523
            E A+   + K  +VE+KGLGTPATRAG+IE+L+  GFVER KK+L++T+KG  L+ +++D
Sbjct  481  EHASAKEFAKLEDVEHKGLGTPATRAGVIEKLVRSGFVERKKKQLFPTEKGTELIKVMPD  540

Query  524  TFKSAETTAKWEMELTEIAQG  544
            T+KS   TA WE  L  + +G
Sbjct  541  TLKSVKLTAEWEERLGAVERG  561

44) HMPREF0389_00190 in NC_016630


> NC_004668_R1|30|G30|29376814|NP_815968.1|Enterococcus_faecalis_V583|-|30310..32427|topB-2|EF2312|DNA 
topoisomerase III
Length=705

 Score =  435 bits (1639),  Expect = 3e-123, Method: Compositional matrix adjust.
 Identities = 268/585 (46%), Positives = 396/585 (68%), Gaps = 21/585 (3%)

Query  4    KLVIAEKPSVAISIAKVIGAKNKKDGYYEGNGYKVSWCVGHLIQMANPDAYDEKYAKWKI  63
            +LVIAEKPSV+++++KV+GAK++ DGY EG G  VSWC+GHL+++A +DAYD +Y+KW+ 
Sbjct  2    QLVIAEKPSVGMALSKVLGAKSRGDGYMEGGGWLVSWCIGHLVELAPADAYDPRYSKWNY  61

Query  64   DDLPIITKEYKYEVAKATKKQFAVLKKLMNDKEIDTVINACDAGREGEAIFRLVYLQASC  123
             DLPI+ K  +++V   TKKQF VLK L++  ++ ++I A DAGREGE IFRL Y   +C
Sbjct  62   ADLPILPKPWQFQVLPDTKKQFEVLKTLIHRADVTALICATDAGREGELIFRLTYHLCGC  121

Query  124  KKKMKRLWISSMEDSAIKDGFDNLKDGNVYDNLFESAQARAIADWLVGMNISRLYSCLYK  183
             K +KRLWISSME++AI+ GFDNL DG+ YDNL+ +A  RA ADWL+G+N +RL++ LY+
Sbjct  122  TKPVKRLWISSMEEAAIQKGFDNLLDGKNYDNLYAAALCRAKADWLIGINGTRLFTTLYQ  181

Query  184  -QNYSVGRVQTPTLSMIVKRDDEIANFKKEKYYTVELELDGFTLSTERIDSLEVAEQLKN  242
             ++ +VGRVQTPTL+++  R+  I+ F+KEK+YTVELEL+GF  ++ER+ S   A +L+ 
Sbjct  182  GKSLNVGRVQTPTLALLAEREAAISGFQKEKFYTVELELEGFRAASERFASKTDAGRLRT  241

Query  243  LLEC---RIEITDVIQTEKITKPDLPFDLTTLQRECNKHFGYSAKQTLDYAQSLYEKKLI  299
               C      +  V Q EK  +P   +DLTTLQRE N+ F+Y+A+QTLDY Q+LYEK+L 
Sbjct  242  --GCVGKPATVQTVSQKEKTERPPKLYDLTTLQREANRLFDYTAQQTLDYLQALYEKRLA  299

Query  300  TYPRTDSRCLTEDM---ITSTVNNILGKNDFDTE-RIRV----VFNSKKVTDHHAIIPTV  351
            TYPRTDSR LTEDM   + +  +++ +   F ++  + V    V+++ KVTDHHAI+PT 
Sbjct  300  TYPRTDSRYLTEDMAAGLPALCQSVAAALPFAADLSLPVNAAQVIDNSKVTDHHAILPTT  359

Query  352  SSMSEDLSSIPESEAKVYRLISNKLHASVGYPLIENTTKIVATFDGFEFTSSGK------  405
             +   DLS++P +E ++  L++ +L  +VG P     T +    +G  F++ GK      
Sbjct  360  EAAKTDLSALPSGEKNILFLVAARLLCAVGEPHTYAETAVTLECGGAVFSAKGKTETAAG  419

Query  406  -VIVDEGFTKYLKEYMSKKNEEPVLPEINVGDVLeikekeikekYTQAPKHFTENTLLKA  464
               ++++F   LK    + +  P LP +  G+ L      IKE  T +P HFTE+TLL A
Sbjct  420  WTAMEQAFHATLKKKPKQPEPSPPLPALTKGQKLTAGGASIKEGATSPPAHFTEDTLLSA  479

Query  465  MEIAGNDGLDKNVEVERKGLGTPATRAGIIENLIYKGFIERDKKNLIATNKGISLITIVA  524
            ME A+   + K  +VE+KGLGTPATRAG+IE+L+  GF+ER KK+L++T+KG  LI +++
Sbjct  480  MEHASAKEFAKLEDVEHKGLGTPATRAGVIEKLVRSGFVERKKKQLFPTEKGTELIKVMP  539

Query  525  DTFKSAETTAKWEMELSDISQGKSSKEEFLNTIEHEIRNELSHYK  569
            DT+KS   TA WE  L+ + +G  S E+F+  I   + + +  Y+
Sbjct  540  DTLKSVKLTAEWEERLGAVERGELSPEDFMAGITAMLTELVKSYQ  584

45) SCI_1283 in NC_022238


> NC_004668_R1|30|G30|29376814|NP_815968.1|Enterococcus_faecalis_V583|-|30310..32427|topB-2|EF2312|DNA 
topoisomerase III
Length=705

 Score =  434 bits (1636),  Expect = 6e-123, Method: Compositional matrix adjust.
 Identities = 263/583 (46%), Positives = 387/583 (67%), Gaps = 17/583 (2%)

Query  1    MKLVIAEKPSVAISIAKVIGANKKKDGYYEGNGYKVSWCVGHLIQMANPDAYNEKYAKWN  60
            M+LVIAEKPSV+++++KV+GA+ + DGY EG G  VSWC+GHL+++A +DAY+ +Y+KWN
Sbjct  1    MQLVIAEKPSVGMALSKVLGAKSRGDGYMEGGGWLVSWCIGHLVELAPADAYDPRYSKWN  60

Query  61   IEDLPIIPSDYKYEVAKATKKQFNILKKLMNDKEIDTVINACDAGREGESIFRLVYSEAK  120
              DLPI+P   +++V   TKKQF++LK L++  ++ ++I A DAGREGE IFRL Y    
Sbjct  61   YADLPILPKPWQFQVLPDTKKQFEVLKTLIHRADVTALICATDAGREGELIFRLTYHLCG  120

Query  121  CKKKMQRLWISSMEDSAIKEGFSNLKNGEDYDNLFESAQARAIADWLVGMNISRLYSCLY  180
            C K ++RLWISSME++AI+ GF NL +G +YDNL+ +A  RA ADWL+G+N +RL++ LY
Sbjct  121  CTKPVKRLWISSMEEAAIQKGFDNLLDGKNYDNLYAAALCRAKADWLIGINGTRLFTTLY  180

Query  181  Q-QNYSVGRVQTPTLYMIVKRDDEISNFKKEKYYTVELSTNGFTLSTDRIDDEVAAEQL-  238
            Q ++ +VGRVQTPTL ++  R+  IS F+KEK+YTVEL  +GF  +++R+     A +L 
Sbjct  181  QGKSLNVGRVQTPTLALLAEREAAISGFQKEKFYTVELELEGFRAASERFASKTDAGRLR  240

Query  239  LNLVGDKIEIIDVIQKEKITKPDLPFDLTTLQRECNKYFGYSAKQTLDYAQSLYEKKLIT  298
               VG    +  V QKEK  +P   +DLTTLQRE N+ F+Y+A+QTLDY Q+LYEK+L T
Sbjct  241  TGCVGKPATVQTVSQKEKTERPPKLYDLTTLQREANRLFDYTAQQTLDYLQALYEKRLAT  300

Query  299  YPRTDSRCLTEDM---ITSTVNNILGKNDFDTE-----RIKVVFDFKKVTDHHAIIPTVS  350
            YPRTDSR LTEDM   + +  +++ +   F ++         V+D  KVTDHHAI+PT  
Sbjct  301  YPRTDSRYLTEDMAAGLPALCQSVAAALPFAADLSLPVNAAQVIDNSKVTDHHAILPTTE  360

Query  351  SLSEDLSGIPESEAKVYRLISNKLHASVGYPLIENTTKIVASFDGFEFTSAGK-------  403
            +   DLS++P +E ++  L++ +L  +VG P     T +    +G  F++ GK       
Sbjct  361  AAKTDLSALPSGEKNILFLVAARLLCAVGEPHTYAETAVTLECGGAVFSAKGKTETAAGW  420

Query  404  VVKDDGFTKYLKDYKSKKNEDIELPDVKVGDVFEVENKEIKEKFTQPQKHFTEDTLLKSM  463
               +++F   LK    + +    LP +  G+ +      IKE  T P  HFTEDTLL +M
Sbjct  421  TAMEQAFHATLKKKPKQPEPSPPLPALTKGQKLTAGGASIKEGATSPPAHFTEDTLLSAM  480

Query  464  EIAGNEALEKGVEVERKGLGTPATRAGIIENLIFKGFVERDKKNLIATHKGISLVTIVSD  523
            E A+   + K  +VE+KGLGTPATRAG+IE+L+  GFVER KK+L++T+KG  L+ +++D
Sbjct  481  EHASAKEFAKLEDVEHKGLGTPATRAGVIEKLVRSGFVERKKKQLFPTEKGTELIKVMPD  540

Query  524  SFKSAETTAKWEMELSDIAQGKSSKEEFLKDIENEIKEAVMTY  566
            ++KS   TA WE  L+ + +G  S E+F+ +I   + E V +Y
Sbjct  541  TLKSVKLTAEWEERLGAVERGELSPEDFMAGITAMLTELVKSY  583

46) SCRE_1224 in NC_022236


> NC_004668_R1|30|G30|29376814|NP_815968.1|Enterococcus_faecalis_V583|-|30310..32427|topB-2|EF2312|DNA 
topoisomerase III
Length=705

 Score =  434 bits (1636),  Expect = 6e-123, Method: Compositional matrix adjust.
 Identities = 263/583 (46%), Positives = 387/583 (67%), Gaps = 17/583 (2%)

Query  1    MKLVIAEKPSVAISIAKVIGANKKKDGYYEGNGYKVSWCVGHLIQMANPDAYNEKYAKWN  60
            M+LVIAEKPSV+++++KV+GA+ + DGY EG G  VSWC+GHL+++A +DAY+ +Y+KWN
Sbjct  1    MQLVIAEKPSVGMALSKVLGAKSRGDGYMEGGGWLVSWCIGHLVELAPADAYDPRYSKWN  60

Query  61   IEDLPIIPSDYKYEVAKATKKQFNILKKLMNDKEIDTVINACDAGREGESIFRLVYSEAK  120
              DLPI+P   +++V   TKKQF++LK L++  ++ ++I A DAGREGE IFRL Y    
Sbjct  61   YADLPILPKPWQFQVLPDTKKQFEVLKTLIHRADVTALICATDAGREGELIFRLTYHLCG  120

Query  121  CKKKMQRLWISSMEDSAIKEGFSNLKNGEDYDNLFESAQARAIADWLVGMNISRLYSCLY  180
            C K ++RLWISSME++AI+ GF NL +G +YDNL+ +A  RA ADWL+G+N +RL++ LY
Sbjct  121  CTKPVKRLWISSMEEAAIQKGFDNLLDGKNYDNLYAAALCRAKADWLIGINGTRLFTTLY  180

Query  181  Q-QNYSVGRVQTPTLYMIVKRDDEISNFKKEKYYTVELSTNGFTLSTDRIDDEVAAEQL-  238
            Q ++ +VGRVQTPTL ++  R+  IS F+KEK+YTVEL  +GF  +++R+     A +L 
Sbjct  181  QGKSLNVGRVQTPTLALLAEREAAISGFQKEKFYTVELELEGFRAASERFASKTDAGRLR  240

Query  239  LNLVGDKIEIIDVIQKEKITKPDLPFDLTTLQRECNKYFGYSAKQTLDYAQSLYEKKLIT  298
               VG    +  V QKEK  +P   +DLTTLQRE N+ F+Y+A+QTLDY Q+LYEK+L T
Sbjct  241  TGCVGKPATVQTVSQKEKTERPPKLYDLTTLQREANRLFDYTAQQTLDYLQALYEKRLAT  300

Query  299  YPRTDSRCLTEDM---ITSTVNNILGKNDFDTE-----RIKVVFDFKKVTDHHAIIPTVS  350
            YPRTDSR LTEDM   + +  +++ +   F ++         V+D  KVTDHHAI+PT  
Sbjct  301  YPRTDSRYLTEDMAAGLPALCQSVAAALPFAADLSLPVNAAQVIDNSKVTDHHAILPTTE  360

Query  351  SLSEDLSGIPESEAKVYRLISNKLHASVGYPLIENTTKIVASFDGFEFTSAGK-------  403
            +   DLS++P +E ++  L++ +L  +VG P     T +    +G  F++ GK       
Sbjct  361  AAKTDLSALPSGEKNILFLVAARLLCAVGEPHTYAETAVTLECGGAVFSAKGKTETAAGW  420

Query  404  VVKDDGFTKYLKDYKSKKNEDIELPDVKVGDVFEVENKEIKEKFTQPQKHFTEDTLLKSM  463
               +++F   LK    + +    LP +  G+ +      IKE  T P  HFTEDTLL +M
Sbjct  421  TAMEQAFHATLKKKPKQPEPSPPLPALTKGQKLTAGGASIKEGATSPPAHFTEDTLLSAM  480

Query  464  EIAGNEALEKGVEVERKGLGTPATRAGIIENLIFKGFVERDKKNLIATHKGISLVTIVSD  523
            E A+   + K  +VE+KGLGTPATRAG+IE+L+  GFVER KK+L++T+KG  L+ +++D
Sbjct  481  EHASAKEFAKLEDVEHKGLGTPATRAGVIEKLVRSGFVERKKKQLFPTEKGTELIKVMPD  540

Query  524  SFKSAETTAKWEMELSDIAQGKSSKEEFLKDIENEIKEAVMTY  566
            ++KS   TA WE  L+ + +G  S E+F+ +I   + E V +Y
Sbjct  541  TLKSVKLTAEWEERLGAVERGELSPEDFMAGITAMLTELVKSY  583

47) SCR2_1224 in NC_022245


> NC_004668_R1|30|G30|29376814|NP_815968.1|Enterococcus_faecalis_V583|-|30310..32427|topB-2|EF2312|DNA 
topoisomerase III
Length=705

 Score =  434 bits (1636),  Expect = 6e-123, Method: Compositional matrix adjust.
 Identities = 263/583 (46%), Positives = 387/583 (67%), Gaps = 17/583 (2%)

Query  1    MKLVIAEKPSVAISIAKVIGANKKKDGYYEGNGYKVSWCVGHLIQMANPDAYNEKYAKWN  60
            M+LVIAEKPSV+++++KV+GA+ + DGY EG G  VSWC+GHL+++A +DAY+ +Y+KWN
Sbjct  1    MQLVIAEKPSVGMALSKVLGAKSRGDGYMEGGGWLVSWCIGHLVELAPADAYDPRYSKWN  60

Query  61   IEDLPIIPSDYKYEVAKATKKQFNILKKLMNDKEIDTVINACDAGREGESIFRLVYSEAK  120
              DLPI+P   +++V   TKKQF++LK L++  ++ ++I A DAGREGE IFRL Y    
Sbjct  61   YADLPILPKPWQFQVLPDTKKQFEVLKTLIHRADVTALICATDAGREGELIFRLTYHLCG  120

Query  121  CKKKMQRLWISSMEDSAIKEGFSNLKNGEDYDNLFESAQARAIADWLVGMNISRLYSCLY  180
            C K ++RLWISSME++AI+ GF NL +G +YDNL+ +A  RA ADWL+G+N +RL++ LY
Sbjct  121  CTKPVKRLWISSMEEAAIQKGFDNLLDGKNYDNLYAAALCRAKADWLIGINGTRLFTTLY  180

Query  181  Q-QNYSVGRVQTPTLYMIVKRDDEISNFKKEKYYTVELSTNGFTLSTDRIDDEVAAEQL-  238
            Q ++ +VGRVQTPTL ++  R+  IS F+KEK+YTVEL  +GF  +++R+     A +L 
Sbjct  181  QGKSLNVGRVQTPTLALLAEREAAISGFQKEKFYTVELELEGFRAASERFASKTDAGRLR  240

Query  239  LNLVGDKIEIIDVIQKEKITKPDLPFDLTTLQRECNKYFGYSAKQTLDYAQSLYEKKLIT  298
               VG    +  V QKEK  +P   +DLTTLQRE N+ F+Y+A+QTLDY Q+LYEK+L T
Sbjct  241  TGCVGKPATVQTVSQKEKTERPPKLYDLTTLQREANRLFDYTAQQTLDYLQALYEKRLAT  300

Query  299  YPRTDSRCLTEDM---ITSTVNNILGKNDFDTE-----RIKVVFDFKKVTDHHAIIPTVS  350
            YPRTDSR LTEDM   + +  +++ +   F ++         V+D  KVTDHHAI+PT  
Sbjct  301  YPRTDSRYLTEDMAAGLPALCQSVAAALPFAADLSLPVNAAQVIDNSKVTDHHAILPTTE  360

Query  351  SLSEDLSGIPESEAKVYRLISNKLHASVGYPLIENTTKIVASFDGFEFTSAGK-------  403
            +   DLS++P +E ++  L++ +L  +VG P     T +    +G  F++ GK       
Sbjct  361  AAKTDLSALPSGEKNILFLVAARLLCAVGEPHTYAETAVTLECGGAVFSAKGKTETAAGW  420

Query  404  VVKDDGFTKYLKDYKSKKNEDIELPDVKVGDVFEVENKEIKEKFTQPQKHFTEDTLLKSM  463
               +++F   LK    + +    LP +  G+ +      IKE  T P  HFTEDTLL +M
Sbjct  421  TAMEQAFHATLKKKPKQPEPSPPLPALTKGQKLTAGGASIKEGATSPPAHFTEDTLLSAM  480

Query  464  EIAGNEALEKGVEVERKGLGTPATRAGIIENLIFKGFVERDKKNLIATHKGISLVTIVSD  523
            E A+   + K  +VE+KGLGTPATRAG+IE+L+  GFVER KK+L++T+KG  L+ +++D
Sbjct  481  EHASAKEFAKLEDVEHKGLGTPATRAGVIEKLVRSGFVERKKKQLFPTEKGTELIKVMPD  540

Query  524  SFKSAETTAKWEMELSDIAQGKSSKEEFLKDIENEIKEAVMTY  566
            ++KS   TA WE  L+ + +G  S E+F+ +I   + E V +Y
Sbjct  541  TLKSVKLTAEWEERLGAVERGELSPEDFMAGITAMLTELVKSY  583

48) SIR_1325 in NC_022246


> NC_004668_R1|30|G30|29376814|NP_815968.1|Enterococcus_faecalis_V583|-|30310..32427|topB-2|EF2312|DNA 
topoisomerase III
Length=705

 Score =  419 bits (1579),  Expect = 2e-118, Method: Compositional matrix adjust.
 Identities = 267/584 (46%), Positives = 394/584 (68%), Gaps = 17/584 (2%)

Query  1    MELVIAEKPSVALSIAKVIGAKNKKDGYYEGNGYRVSWCVGHLIQMANPDSYDEKYAKWN  60
            M+LVIAEKPSV+++++KV+GAK++ DGY EG G  VSWC+GHL+++A +D+YD +Y+KWN
Sbjct  1    MQLVIAEKPSVGMALSKVLGAKSRGDGYMEGGGWLVSWCIGHLVELAPADAYDPRYSKWN  60

Query  61   IDDLPIIPSEYQYEVAKATKKQFNTLKKLMNDKEIDTVINACDAGQEGEAIFRLVYLQAN  120
              DLPI+P   Q++V   TKKQF+ LK L++  ++ ++I A DAG+EGE IFRL Y    
Sbjct  61   YADLPILPKPWQFQVLPDTKKQFEVLKTLIHRADVTALICATDAGREGELIFRLTYHLCG  120

Query  121  CKKKMKRLWISSMEDSAIkdgfdklkdgkdydNLFESAQARAIADWLVGMNISRLYSCLY  180
            C K +KRLWISSME++AI+ GFD+L DGK+YDNL+ +A  RA ADWL+G+N +RL++ LY
Sbjct  121  CTKPVKRLWISSMEEAAIQKGFDNLLDGKNYDNLYAAALCRAKADWLIGINGTRLFTTLY  180

Query  181  K-QNYSVGRVQTPTLSMIVKRDDEIANFKKEKYYTVELELDGFTLSTERIDSLEVAEQLK  239
            + ++ +VGRVQTPTL+++  R+  I+ F+KEK+YTVELEL+GF  ++ER+ S   A +L+
Sbjct  181  QGKSLNVGRVQTPTLALLAEREAAISGFQKEKFYTVELELEGFRAASERFASKTDAGRLR  240

Query  240  NL-LENRIEITDVIQKEKVTKPDLPFDLTTLQRECNKYFGYSAKQTLDYAQSLYEKKLIT  298
               + +   +  V QKEK  +P   +DLTTLQRE N+ F+Y+A+QTLDY Q+LYEK+L T
Sbjct  241  TGCVGKPATVQTVSQKEKTERPPKLYDLTTLQREANRLFDYTAQQTLDYLQALYEKRLAT  300

Query  299  YPRTDSRCLTEDM---ITSTVNNILGKNDFDTE-----RIKTVFNSKKVTDHHAIIPTVS  350
            YPRTDSR LTEDM   + +  +++ +   F ++         V+++ KVTDHHAI+PT  
Sbjct  301  YPRTDSRYLTEDMAAGLPALCQSVAAALPFAADLSLPVNAAQVIDNSKVTDHHAILPTTE  360

Query  351  SLSEDISKLPESEAKVYRLISNKFHASVGYSLTQNTTKIVAEFDGFEFTSSGK-------  403
            +   D+S LP +E ++  L++ ++  +VG + T   T +  E +G  F++ GK       
Sbjct  361  AAKTDLSALPSGEKNILFLVAARLLCAVGEPHTYAETAVTLECGGAVFSAKGKTETAAGW  420

Query  404  VIKDEGFskylkeykskkseDAVLPDVSVGDVLTIENKEIKEKFTQPPKHFTEDTLLKAM  463
               +++F   LK    +    + LP ++ G+ LT     IKE  T PP HFTEDTLL AM
Sbjct  421  TAMEQAFHATLKKKPKQPEPSPPLPALTKGQKLTAGGASIKEGATSPPAHFTEDTLLSAM  480

Query  464  ELAGNDAFEKGVEVEREGLGTPATRAGIIENLIYKEFIERDKKNLIATPKGKSLIEIVAD  523
            E A+   F K  +VE+ GLGTPATRAG+IE+L+   F+ER KK+L++T KG  LI +++D
Sbjct  481  EHASAKEFAKLEDVEHKGLGTPATRAGVIEKLVRSGFVERKKKQLFPTEKGTELIKVMPD  540

Query  524  NFKSAEMTAQWEMELSEIAQGKSSKKEFLEKIEEQIKHTVEEHQ  567
             +KS  +TA+WE  L+ + +G  S  +F+  I   + + V   Q
Sbjct  541  TLKSVKLTAEWEERLGAVERGELSPEDFMAGITAMLTELVKSYQ  584

49) SAIL_7480 in NC_021507


> NC_004668_R1|30|G30|29376814|NP_815968.1|Enterococcus_faecalis_V583|-|30310..32427|topB-2|EF2312|DNA 
topoisomerase III
Length=705

 Score =  418 bits (1573),  Expect = 5e-118, Method: Compositional matrix adjust.
 Identities = 246/585 (43%), Positives = 386/585 (66%), Gaps = 16/585 (2%)

Query  1    MKLVIAEKPSVAVTIAKVIGARTRKNGYYEGGGYIVSWCVGHLIQMASPERHDEKWKKWS  60
            M+LVIAEKPSV+++++KV+GA++R +GY EGGG +VSWC+GHL+++A+++  D +  KW+
Sbjct  1    MQLVIAEKPSVGMALSKVLGAKSRGDGYMEGGGWLVSWCIGHLVELAPADAYDPRYSKWN  60

Query  61   IENLPIIPEEYIYEVSKSTKKQYGILKKLLNDKNIDTVINACDAGREGELIFRLVYNQAK  120
              +LPI+P    ++V   TKKQ+ +LK L++  ++ ++I A DAGREGELIFRL Y+   
Sbjct  61   YADLPILPKPWQFQVLPDTKKQFEVLKTLIHRADVTALICATDAGREGELIFRLTYHLCG  120

Query  121  CKKKIKRLWISSMENKAIEDGFRNLKEGENFEDLYRSASARAIADWLVGMNLSRLYSCIY  180
            C K +KRLWISSME+ AI+ GF NL +G N+++LY +A  RA ADWL+G+N +RL++ +Y
Sbjct  121  CTKPVKRLWISSMEEAAIQKGFDNLLDGKNYDNLYAAALCRAKADWLIGINGTRLFTTLY  180

Query  181  KE-TYSVGRVQTPTLYLIAKRDSEINLFKKKKYYTVDLSYKGLKLVSDRIDRIEVAEQL-  238
            +  + +VGRVQTPTL L+A R++ I+ F+K K+YTV+L   G++  S+R+     A +L 
Sbjct  181  QGKSLNVGRVQTPTLALLAEREAAISGFQKEKFYTVELELEGFRAASERFASKTDAGRLR  240

Query  239  LNLLEDEIVITEVEDKEISTKPDKPYDLTTLQREANKYFGYSANDTLNLAQALYEKKLIT  298
               +     +  V +KE + +P K YDLTTLQREAN+ F+Y+A++TL+  QALYEK+L T
Sbjct  241  TGCVGKPATVQTVSQKEKTERPPKLYDLTTLQREANRLFDYTAQQTLDYLQALYEKRLAT  300

Query  299  YPRTDSRYLTDDMVTTMKELLEGLEEDFKINES-----NFKSIFNSSKVTDHYAIIPTIS  353
            YPRTDSRYLT+DM + +  L +++   + +        N   ++++SKVTDH AI+PT  
Sbjct  301  YPRTDSRYLTEDMAAGLPALCQSVAAALPFAADLSLPVNAAQVIDNSKVTDHHAILPTTE  360

Query  354  GIGKA-KDLTDKESKIYNLIKDKLLASCSDNLKESSRKIRYEYDKFNFNASGK-------  405
            +       L   E +I  L+  +LL + ++    +   +  E +   F+A GK       
Sbjct  361  AAKTDLSALPSGEKNILFLVAARLLCAVGEPHTYAETAVTLECGGAVFSAKGKTETAAGW  420

Query  406  TIIDEGYTKYLKSYGKEKQ-KKELPDIKTGDKIKLTSKNISEKFTKAPSHYNEDTLLKTM  464
            T +++++   LK   K+ +    LP +  G+K+   + +I E  T +P+H+ EDTLL +M
Sbjct  421  TAMEQAFHATLKKKPKQPEPSPPLPALTKGQKLTAGGASIKEGATSPPAHFTEDTLLSAM  480

Query  465  ENAGVESLDKAIEVERKGLGTPATRAGIIENLIHKDLIRRDKKNLLVTEKGNRLVSIVED  524
            E+A+   + K  +VE+KGLGTPATRAG+IE+L++ +++ R KK+L+ TEKG  L+ ++ D
Sbjct  481  EHASAKEFAKLEDVEHKGLGTPATRAGVIEKLVRSGFVERKKKQLFPTEKGTELIKVMPD  540

Query  525  KFKSAETTSEWEMKLAKISSGEVDKEDFLREIEDSIKELVDRYKN  569
             +KS   T+EWE +L+ +  GE+  EDF+  I   + ELV  Y+ 
Sbjct  541  TLKSVKLTAEWEERLGAVERGELSPEDFMAGITAMLTELVKSYQG  585

50) Rxyl_0752 in NC_008148


> NC_004668_R1|30|G30|29376814|NP_815968.1|Enterococcus_faecalis_V583|-|30310..32427|topB-2|EF2312|DNA 
topoisomerase III
Length=705

 Score =  417 bits (1570),  Expect = 1e-117, Method: Compositional matrix adjust.
 Identities = 287/714 (41%), Positives = 446/714 (63%), Gaps = 41/714 (5%)

Query  1    MRLIVAEKPSVGRDIAGALGRHRREGDALVGSGWVVTWALGHLAELAPPDAYGAEYKRWS  60
            M+L++AEKPSVG  ++  LG   R ++ + G+GW+V+W +GHL ELAP+DAY++ Y +W+
Sbjct  1    MQLVIAEKPSVGMALSKVLGAKSRGDGYMEGGGWLVSWCIGHLVELAPADAYDPRYSKWN  60

Query  61   LQNLPILPERFRVRVNPRTRERFEAVRRWMRDPSVTEVVNACDAGREGELIFAYLYQLSR  120
              +LPILP   + +V P T+ +FE ++  ++ + VT ++ A DAGREGELIF   Y+L  
Sbjct  61   YADLPILPKPWQFQVLPDTKKQFEVLKTLIHRADVTALICATDAGREGELIFRLTYHLCG  120

Query  121  CEKPVRRLWVSSLTPEAIREGFGSLRDGPSMKPLEDAARSRAEADWIVGMNATRAYSVRF  180
            C KPV+RLW+SS+   AI+ GF++L DG +   L  AA  RA ADW++G+N+TR ++  +
Sbjct  121  CTKPVKRLWISSMEEAAIQKGFDNLLDGKNYDNLYAAALCRAKADWLIGINGTRLFTTLY  180

Query  181  SRPGDVLSVGRVQTPTlrllverereIEDFRPERFFTVHARFARDGKTYDGLWFREKESR  240
               G  L+VGRVQTPTL LL ERE  I +F+ E+F+TV+  +  +G       FR    R
Sbjct  181  --QGKSLNVGRVQTPTLALLAEREAAISGFQKEKFYTVE--LELEG-------FRAASER  229

Query  241  LKEREAAEQIAEKVRGGTGVVKKAERRRTSERPPLLYDLTELQRNANARYGFTAERTLRA  300
            +  +  A ++     G  + V+   ++  +ERPP LYDLT LQR+AN  +++TA++TL  
Sbjct  230  FASKTDAGRLRTGCVGKPATVQTVSQKEKTERPPKLYDLTTLQREANRLFDYTAQQTLDY  289

Query  301  AQALYEERKLITYPRTSSRYLSGDMVGTLKRRVEAAGGLPELAPFAGRLLAAGSLPV-GR  359
             QALY E++L TYPRT SRYL+ DM + L    ++ ++   L PFA+ L    SLPV + 
Sbjct  290  LQALY-EKRLATYPRTDSRYLTEDMAAGLPALCQSVAA--AL-PFAADL----SLPVNAA  341

Query  360  RVVDDSKVTDHHAIVPT---DRKPSGGLPPDEAKVYDLVARRFLAVFFPAARFENTTVVT  416
            +V+D+SKVTDHHAI+PT    +   ++LP++E ++  LVA R+L     +  + +T+V  
Sbjct  342  QVIDNSKVTDHHAILPTTEAAKTDLSALPSGEKNILFLVAARLLCAVGEPHTYAETAVTL  401

Query  417  EARGETFLSKGRVVLEAGWREL---YPDGVGGRKEKEP---PALPPVEAGQEWRVAKVGV  470
            E  G  F +KG+    AGW  +   +   +  +K K+P   P+LP++  GQ    +  ++
Sbjct  402  ECGGAVFSAKGKTETAAGWTAMEQAFHATL-KKKPKQPEPSPPLPALTKGQKLTAGGASI  460

Query  471  KEGETKPPPRYSESALLGAMETAGKLVEDEELRQQMKDSGLGTPATRAAIIERLIKVGYV  530
            KEG T PP++++E +LL+AME A+    +    +++ + GLGTPATRA++IE+L++ G+V
Sbjct  461  KEGATSPPAHFTEDTLLSAMEHAS--AKEFAKLEDVEHKGLGTPATRAGVIEKLVRSGFV  518

Query  531  EREKKALVPTAKGRALISLLADSPLSSPEMTARWERRLARIERGEERRPDFMSDISGFAA  590
            ER KK L PT KG  LI +++D+ L S  +TA WE RL+ +ERGE    DFM++I++  +
Sbjct  519  ERKKKQLFPTEKGTELIKVMPDT-LKSVKLTAEWEERLGAVERGELSPEDFMAGITAMLT  577

Query  591  SVVEGVRRMEGEKIaapggggealgaCPKCGSPVVETKKAYGCSAWRKT-GCDFAIWKR-  648
             +V + + +     A +++G   +G CP+CG  VVE KK++ C +W  + +CDFA+WK  
Sbjct  578  ELVKSYQGVTVASAALSASGRTVIGICPRCGKNVVEGKKSFFCEGWNAAPACDFALWKND  637

Query  649  ----VAGKRVSESQARQLLAKGRTARLKGFKSRAGKPFSAALVLD--GEHRVRL  696
                   K ++   A  LL KGR A    F  + G  + A +V++  GE  VR+
Sbjct  638  RFFTSKHKELTRKAAAALLKKGRVAMTGLFSEKKGVLYDAIVVMEDTGEKFVRF  691

51) SPAP_0887 in NC_014494


> NC_004668_R1|30|G30|29376814|NP_815968.1|Enterococcus_faecalis_V583|-|30310..32427|topB-2|EF2312|DNA 
topoisomerase III
Length=705

 Score =  410 bits (1541),  Expect = 2e-115, Method: Compositional matrix adjust.
 Identities = 249/585 (43%), Positives = 387/585 (67%), Gaps = 16/585 (2%)

Query  1    MKLVIAEKPSVAVTIAKVIGARTRKNGYYEGGGYIVSWCVGHLIQMARPDKIDEKWKKWA  60
            M+LVIAEKPSV+++++KV+GA++R +GY EGGG +VSWC+GHL+++A +D  D +  KW 
Sbjct  1    MQLVIAEKPSVGMALSKVLGAKSRGDGYMEGGGWLVSWCIGHLVELAPADAYDPRYSKWN  60

Query  61   IDTLPIIPEEYIYEVSKSTKKQYGVLKTLLNDKNIDTVINACDAGREGELIFRLVYNQAK  120
               LPI+P    ++V   TKKQ+ VLKTL++  ++ ++I A DAGREGELIFRL Y+   
Sbjct  61   YADLPILPKPWQFQVLPDTKKQFEVLKTLIHRADVTALICATDAGREGELIFRLTYHLCG  120

Query  121  CKKKIQRLWISSMENKAIEDGFRNLKDGENFEDLYRSASARAIADWLVGMNLSRLYSCIY  180
            C K ++RLWISSME+ AI+ GF NL DG N+++LY +A  RA ADWL+G+N +RL++ +Y
Sbjct  121  CTKPVKRLWISSMEEAAIQKGFDNLLDGKNYDNLYAAALCRAKADWLIGINGTRLFTTLY  180

Query  181  KE-TYSVGRVQTPTLYLIAKRDSEINLFKKQKYYTVDLSYGGLKLVSDRIDRIEVAEQL-  238
            +  + +VGRVQTPTL L+A R++ I+ F+K+K+YTV+L   G++  S+R+     A +L 
Sbjct  181  QGKSLNVGRVQTPTLALLAEREAAISGFQKEKFYTVELELEGFRAASERFASKTDAGRLR  240

Query  239  LNLLEDEIVITEVEDKEISTKPDKPYDLTTLQREANKYFGYSANDTLNLAQGLYEKKLIT  298
               +     +  V +KE + +P K YDLTTLQREAN+ F+Y+A++TL+  Q+LYEK+L T
Sbjct  241  TGCVGKPATVQTVSQKEKTERPPKLYDLTTLQREANRLFDYTAQQTLDYLQALYEKRLAT  300

Query  299  YPRTDSRYLTNDMVTTMKellegleegFKINES-----NFKSIFNSSKVTDHYAIIPTIS  353
            YPRTDSRYLT+DM + +  L +++  ++ +        N   ++++SKVTDH AI+PT  
Sbjct  301  YPRTDSRYLTEDMAAGLPALCQSVAAALPFAADLSLPVNAAQVIDNSKVTDHHAILPTTE  360

Query  354  GIGKA-KDLSDKESKIYNLIKDKLLASCSDNLKESSRKIRYKYDKFNFSASGK-------  405
            +       L+  E +I  L+  +LL + ++    +   +    +   FSA GK       
Sbjct  361  AAKTDLSALPSGEKNILFLVAARLLCAVGEPHTYAETAVTLECGGAVFSAKGKTETAAGW  420

Query  406  TIIDEGYAKYLKPYGKERQEN-ELPDVKTGDKIKLTSKNISEKFTKAPSHYNEDTLLKAM  464
            T +++++   LK   K+ + +  LP +  G+K+   + +I E  T +P+H+ EDTLL AM
Sbjct  421  TAMEQAFHATLKKKPKQPEPSPPLPALTKGQKLTAGGASIKEGATSPPAHFTEDTLLSAM  480

Query  465  ENAGVESLDKDIEVERKGLGTPATRAGIIENLIHKDLIRRDKKNLLVTEKGNRLVSIVED  524
            E+A+   + K  +VE+KGLGTPATRAG+IE+L++ +++ R KK+L+ TEKG  L+ ++ D
Sbjct  481  EHASAKEFAKLEDVEHKGLGTPATRAGVIEKLVRSGFVERKKKQLFPTEKGTELIKVMPD  540

Query  525  KFKSAETTSEWEMKLAKISSGEVDKEDFLREIEDSIRELVDRYKN  569
             +KS   T+EWE +L+ +  GE+  EDF+  I   + ELV  Y+ 
Sbjct  541  TLKSVKLTAEWEERLGAVERGELSPEDFMAGITAMLTELVKSYQG  585

52) HMPREF0389_00657 in NC_016630


> NC_004668_R1|30|G30|29376814|NP_815968.1|Enterococcus_faecalis_V583|-|30310..32427|topB-2|EF2312|DNA 
topoisomerase III
Length=705

 Score =  407 bits (1532),  Expect = 9e-115, Method: Compositional matrix adjust.
 Identities = 265/584 (46%), Positives = 389/584 (67%), Gaps = 17/584 (2%)

Query  1    MKLVIAEKPSVALSISKIIGAKNKKDGYYEGNGYRVSWCVGHLIQMANPDSYDEKYAKWK  60
            M+LVIAEKPSV++++SK++GAK++ DGY EG G  VSWC+GHL+++A +D+YD +Y+KW+
Sbjct  1    MQLVIAEKPSVGMALSKVLGAKSRGDGYMEGGGWLVSWCIGHLVELAPADAYDPRYSKWN  60

Query  61   IDDLPIIPSEYQYEVAKATKKQFAVLKKLMNDKAIDTVINACDAGREGEAIFRLVYLQAS  120
              DLPI+P   Q++V   TKKQF VLK L++   + ++I A DAGREGE IFRL Y   +
Sbjct  61   YADLPILPKPWQFQVLPDTKKQFEVLKTLIHRADVTALICATDAGREGELIFRLTYHLCG  120

Query  121  CKKKMKRLWISSMEDSAIkdgfdklkdgkdydNLFESAQARAVADWLVGMNISRLYSCLY  180
            C K +KRLWISSME++AI+ GFD+L DGK+YDNL+ +A  RA ADWL+G+N +RL++ LY
Sbjct  121  CTKPVKRLWISSMEEAAIQKGFDNLLDGKNYDNLYAAALCRAKADWLIGINGTRLFTTLY  180

Query  181  K-QNYSVGRVQTPTLAMIVKRDDEITNFKKDKYYTVELSMNGFILSTERIDDEVAAEQL-  238
            + ++ +VGRVQTPTLA++  R+  I+ F+K+K+YTVEL ++GF  ++ER+     A +L 
Sbjct  181  QGKSLNVGRVQTPTLALLAEREAAISGFQKEKFYTVELELEGFRAASERFASKTDAGRLR  240

Query  239  INLVGDKIEITDVIQKEKITKPDLPFDLTTLQRECNKYFGYSAKQTLDYAQSLYEKKLIT  298
               VG    +  V QKEK  +P   +DLTTLQRE N+ F+Y+A+QTLDY Q+LYEK+L T
Sbjct  241  TGCVGKPATVQTVSQKEKTERPPKLYDLTTLQREANRLFDYTAQQTLDYLQALYEKRLAT  300

Query  299  YPRTDSRCLTEDM---ITSTVNNILGKNDFDTG-----RIKTVFNSKKVTDHHAIIPTVS  350
            YPRTDSR LTEDM   + +  +++ +   F ++         V+++ KVTDHHAI+PT  
Sbjct  301  YPRTDSRYLTEDMAAGLPALCQSVAAALPFAADLSLPVNAAQVIDNSKVTDHHAILPTTE  360

Query  351  SLSEDLSGIPESEAKVYRLISNKLHASVGYPLVENTTKIVAEFDGFQFTSTGK-------  403
            +   DLS++P +E ++  L++ +L  +VG P     T +  E +G  F++ GK       
Sbjct  361  AAKTDLSALPSGEKNILFLVAARLLCAVGEPHTYAETAVTLECGGAVFSAKGKTETAAGW  420

Query  404  VIKDEGFTKYLKEYKFNKNEDLELPDVSIGDViiienkeikekYTKPPKHFTEDTLLKAM  463
               +++F   LK    + +    LP ++ G+ +      IKE  T PP HFTEDTLL AM
Sbjct  421  TAMEQAFHATLKKKPKQPEPSPPLPALTKGQKLTAGGASIKEGATSPPAHFTEDTLLSAM  480

Query  464  ELAGNDALEKGVEVEREGLGTPATRAGIIENLIYKEFIERDKKNLIATPKGKSLIEIVVD  523
            E A+   + K  +VE+ GLGTPATRAG+IE+L+   F+ER KK+L++T KG  LI ++ D
Sbjct  481  EHASAKEFAKLEDVEHKGLGTPATRAGVIEKLVRSGFVERKKKQLFPTEKGTELIKVMPD  540

Query  524  NFKSAEMTAQWEMELSEIAQGKSSKKEFLEKIEEQIKHTVEEHQ  567
             +KS  +TA+WE  L+ + +G  S  +F+  I   + + V   Q
Sbjct  541  TLKSVKLTAEWEERLGAVERGELSPEDFMAGITAMLTELVKSYQ  584

53) MGAS10750_Spy1696 in NC_008024


> NC_004668_R1|30|G30|29376814|NP_815968.1|Enterococcus_faecalis_V583|-|30310..32427|topB-2|EF2312|DNA 
topoisomerase III
Length=705

 Score =  405 bits (1525),  Expect = 4e-114, Method: Compositional matrix adjust.
 Identities = 245/585 (42%), Positives = 384/585 (66%), Gaps = 16/585 (2%)

Query  5    MKLVIAEKPSVAVTIAKIIGARTRKNGYYEGNGYIVSWCVGHLIQMASPDKIDEKWKKWT  64
            M+LVIAEKPSV+++++K++GA++R +GY EG G +VSWC+GHL+++A++D  D +  KW 
Sbjct  1    MQLVIAEKPSVGMALSKVLGAKSRGDGYMEGGGWLVSWCIGHLVELAPADAYDPRYSKWN  60

Query  65   IENLPIIPEEYIYEVSKSTKKQYGVLKKLLNDKNINIVINACDAGREGELIFRLVYNQAK  124
              +LPI+P    ++V   TKKQ+ VLK L++  ++  +I A DAGREGELIFRL Y+   
Sbjct  61   YADLPILPKPWQFQVLPDTKKQFEVLKTLIHRADVTALICATDAGREGELIFRLTYHLCG  120

Query  125  CKKKIQRLWISSMENEAIEDGFRNLKDGEKFEDLYRSASARAIADWLVGMNLSRLYSCIY  184
            C K ++RLWISSME+ AI+ GF NL DG ++++LY +A  RA ADWL+G+N +RL++ +Y
Sbjct  121  CTKPVKRLWISSMEEAAIQKGFDNLLDGKNYDNLYAAALCRAKADWLIGINGTRLFTTLY  180

Query  185  KE-TYSVGRVQTPTLYLIAKRDSEINLFKKQKYYTVDLSYGGLKLVSDRIDRIEVAEQL-  242
            +  + +VGRVQTPTL L+A R++ I+ F+K+K+YTV+L   G++  S+R+     A +L 
Sbjct  181  QGKSLNVGRVQTPTLALLAEREAAISGFQKEKFYTVELELEGFRAASERFASKTDAGRLR  240

Query  243  LNLLEDEIVITEVEDKEVSTKPDKPYDLTTLQREANKYFGYSANDTLNLAQALYEKKLIT  302
               +     +  V +KE + +P K YDLTTLQREAN+ F+Y+A++TL+  QALYEK+L T
Sbjct  241  TGCVGKPATVQTVSQKEKTERPPKLYDLTTLQREANRLFDYTAQQTLDYLQALYEKRLAT  300

Query  303  YPRTDSRYLTDDMVNTMKELLEGLEEDfk-----lnksnfksifnsskVTDHYAIIPTIS  357
            YPRTDSRYLT+DM   +  L +++   +          N   ++++SKVTDH AI+PT  
Sbjct  301  YPRTDSRYLTEDMAAGLPALCQSVAAALPFAADLSLPVNAAQVIDNSKVTDHHAILPTTE  360

Query  358  GIGKA-KDLSDKESKVYNLIKDKLLASCSDNLKESSRKIRYEYDKFNFNASGK-------  409
            +       L+  E ++  L+  +LL + ++    +   +  E +   F+A GK       
Sbjct  361  AAKTDLSALPSGEKNILFLVAARLLCAVGEPHTYAETAVTLECGGAVFSAKGKTETAAGW  420

Query  410  TIIDEGYTKYLKAYGKEKQEN-ELPDVKTGDKIKLTSKNISEKFTKAPSHYNEDTLLKAM  468
            T +++++   LK   K+ + +  LP +  G+K+   + +I E  T +P+H+ EDTLL AM
Sbjct  421  TAMEQAFHATLKKKPKQPEPSPPLPALTKGQKLTAGGASIKEGATSPPAHFTEDTLLSAM  480

Query  469  ENAGVESLDKDIEVERKGLGTPATRAGIIENLIHKELIRRDKKNLLVTEKGNRLVSIVED  528
            E+A+   + K  +VE+KGLGTPATRAG+IE+L++  ++ R KK+L+ TEKG  L+ ++ D
Sbjct  481  EHASAKEFAKLEDVEHKGLGTPATRAGVIEKLVRSGFVERKKKQLFPTEKGTELIKVMPD  540

Query  529  KFKSAETTSEWEMKLAKINSGEVDKEDFLREIEDSIRELVDRYKN  573
             +KS   T+EWE +L+ ++ GE+  EDF+  I   + ELV  Y+ 
Sbjct  541  TLKSVKLTAEWEERLGAVERGELSPEDFMAGITAMLTELVKSYQG  585

54) FMG_0956 in NC_010376


> NC_004668_R1|30|G30|29376814|NP_815968.1|Enterococcus_faecalis_V583|-|30310..32427|topB-2|EF2312|DNA 
topoisomerase III
Length=705

 Score =  404 bits (1519),  Expect = 9e-114, Method: Compositional matrix adjust.
 Identities = 245/585 (42%), Positives = 391/585 (67%), Gaps = 16/585 (2%)

Query  1    MKLVIAEKPSVAVTIAKVIGARTRKNGYYEGNGYIVSWCVGHLIQMASPERHDEKWKKWT  60
            M+LVIAEKPSV+++++KV+GA++R +GY EG G +VSWC+GHL+++A+++  D +  KW 
Sbjct  1    MQLVIAEKPSVGMALSKVLGAKSRGDGYMEGGGWLVSWCIGHLVELAPADAYDPRYSKWN  60

Query  61   IENLPIIPEEYIYEVSKSTKKQYGVLKKLLNDKNIDTVINACDAGREGELIFRLVYNQAK  120
              +LPI+P    ++V   TKKQ+ VLK L++  ++ ++I A DAGREGELIFRL Y+   
Sbjct  61   YADLPILPKPWQFQVLPDTKKQFEVLKTLIHRADVTALICATDAGREGELIFRLTYHLCG  120

Query  121  CKKKIQRLWISSMENKAIEDGFRNLKDGEKFEDLYGSASARAIADWLVGMNLSRLYSCIY  180
            C K ++RLWISSME+ AI+ GF NL DG ++++LY++A  RA ADWL+G+N +RL++ +Y
Sbjct  121  CTKPVKRLWISSMEEAAIQKGFDNLLDGKNYDNLYAAALCRAKADWLIGINGTRLFTTLY  180

Query  181  KE-TYSVGRVQTPTLYLIAKRDSEINLFKKQKYYTVDLSYKGLKLVSDRIDKIEVAEQL-  238
            +  + +VGRVQTPTL L+A R++ I+ F+K+K+YTV+L   G++  S+R+     A +L 
Sbjct  181  QGKSLNVGRVQTPTLALLAEREAAISGFQKEKFYTVELELEGFRAASERFASKTDAGRLR  240

Query  239  LNLiedeivitevedkeiSTKPDKPYDLTTLQREANKYFGYSANDTLNMAQGLYEKKLIT  298
               +     +  V +KE + +P K YDLTTLQREAN+ F+Y+A++TL+  Q+LYEK+L T
Sbjct  241  TGCVGKPATVQTVSQKEKTERPPKLYDLTTLQREANRLFDYTAQQTLDYLQALYEKRLAT  300

Query  299  YPRTDSRYLTDDMVTTMKellegleegFKINES-----NFKSIFNSSKVTDHYAIIPTIS  353
            YPRTDSRYLT+DM + +  L +++  ++ +        N   ++++SKVTDH AI+PT  
Sbjct  301  YPRTDSRYLTEDMAAGLPALCQSVAAALPFAADLSLPVNAAQVIDNSKVTDHHAILPTTE  360

Query  354  GI-GKVKDLSDKESKVYNLIKDKLLASCSDNLKESSRKIRYEYDKFNFNASGK-------  405
            +    +  L+  E ++  L+  +LL + ++    +   +  E +   F+A GK       
Sbjct  361  AAKTDLSALPSGEKNILFLVAARLLCAVGEPHTYAETAVTLECGGAVFSAKGKTETAAGW  420

Query  406  TIIDEGYTKYLKAYGKEKQEN-ELPDVKTGDKIKLTSKNISEKFTKAPSHYNEDTLLKAM  464
            T +++++   LK   K+ + +  LP +  G+K+   + +I E  T +P+H+ EDTLL AM
Sbjct  421  TAMEQAFHATLKKKPKQPEPSPPLPALTKGQKLTAGGASIKEGATSPPAHFTEDTLLSAM  480

Query  465  ENAGIESLDKDIEVERKGLGTPATRAGIIENLIHKDLIRRDKKNLLVTEKGNRLVSIVED  524
            E+A+   + K  +VE+KGLGTPATRAG+IE+L++ +++ R KK+L+ TEKG  L+ ++ D
Sbjct  481  EHASAKEFAKLEDVEHKGLGTPATRAGVIEKLVRSGFVERKKKQLFPTEKGTELIKVMPD  540

Query  525  KFKSAKTTSEWEMKLAKISSGEVDKEDFLREIEDSIRELVDRYKN  569
             +KS K T+EWE +L+ +  GE+  EDF+  I   + ELV  Y+ 
Sbjct  541  TLKSVKLTAEWEERLGAVERGELSPEDFMAGITAMLTELVKSYQG  585

55) Apre_1822 in NC_013164


> NC_004668_R1|30|G30|29376814|NP_815968.1|Enterococcus_faecalis_V583|-|30310..32427|topB-2|EF2312|DNA 
topoisomerase III
Length=705

 Score =  400 bits (1506),  Expect = 1e-112, Method: Compositional matrix adjust.
 Identities = 249/586 (43%), Positives = 387/586 (67%), Gaps = 18/586 (3%)

Query  1    MKLVIAEKPSVAVTIAKVIGARTRKNGYYEGGGYIVSWCVGHLIQMASPDKIDEKWKKWT  60
            M+LVIAEKPSV+++++KV+GA++R +GY EGGG +VSWC+GHL+++A++D  D +  KW 
Sbjct  1    MQLVIAEKPSVGMALSKVLGAKSRGDGYMEGGGWLVSWCIGHLVELAPADAYDPRYSKWN  60

Query  61   IENLPIIPEEYIYEVSKSTKKQYGVLKKLLNDKNIDTVINACDAGREGELIFRLVYNQAK  120
              +LPI+P    ++V   TKKQ+ VLK L++  ++ ++I A DAGREGELIFRL Y+   
Sbjct  61   YADLPILPKPWQFQVLPDTKKQFEVLKTLIHRADVTALICATDAGREGELIFRLTYHLCG  120

Query  121  CKKKIQRLWISSMENKAIEDGFRNLKDGENFEDLYRSASARAIVDWLVGMNLSRLYSCIY  180
            C K ++RLWISSME+ AI+ GF NL DG N+++LY +A  RA  DWL+G+N +RL++ +Y
Sbjct  121  CTKPVKRLWISSMEEAAIQKGFDNLLDGKNYDNLYAAALCRAKADWLIGINGTRLFTTLY  180

Query  181  KE-TYSVGRVQTPTLYLIAKRDSEINLFKKQKYYTVDLSYGGLKLVSDRIDKIEVAEQL-  238
            +  + +VGRVQTPTL L+A R++ I+ F+K+K+YTV+L   G++  S+R+     A +L 
Sbjct  181  QGKSLNVGRVQTPTLALLAEREAAISGFQKEKFYTVELELEGFRAASERFASKTDAGRLR  240

Query  239  LNLLEDEIVITEVEDKEISTRPDKPYDLTTLQREANKYFGYSANDTLNLAQGLYEKKLIT  298
               +     +  V +KE + RP K YDLTTLQREAN+ F+Y+A++TL+  Q+LYEK+L T
Sbjct  241  TGCVGKPATVQTVSQKEKTERPPKLYDLTTLQREANRLFDYTAQQTLDYLQALYEKRLAT  300

Query  299  YPRTDSRHLTDDMVNTMKELLEG------FEEDFKINESNFKSIFNSSKVTDHYAIIPTI  352
            YPRTDSR LT+DM   +  L ++      F  D+ +  +    ++++SKVTDH AI+PT 
Sbjct  301  YPRTDSRYLTEDMAAGLPALCQSVAAALPFAADLSLPVNA-AQVIDNSKVTDHHAILPTT  359

Query  353  SGIGKA-KDLSDKESKIYNLIKNKLLASCSDNLKESSRKIRYEYDKFNFNASGK------  405
             +       L+  E +I  L+  +LL + ++    +   +  E +   F+A GK      
Sbjct  360  EAAKTDLSALPSGEKNILFLVAARLLCAVGEPHTYAETAVTLECGGAVFSAKGKTETAAG  419

Query  406  -TVIDEGYTKYLKPYGKERQEN-ELPDVKTGDKIKLTSKNISEKFTKAPSHYNEDTLLKA  463
             T +++++   LK   K+ + +  LP +  G+K+   + +I E  T +P+H+ EDTLL A
Sbjct  420  WTAMEQAFHATLKKKPKQPEPSPPLPALTKGQKLTAGGASIKEGATSPPAHFTEDTLLSA  479

Query  464  MENAGIKSLDKDIEVERKGLGTPATRAGIIENLIHkdlirrdkkkllVTEKGNRLVSIVE  523
            ME+A+ K + K  +VE+KGLGTPATRAG+IE+L++ +++ R KK+L+ TEKG  L+ ++ 
Sbjct  480  MEHASAKEFAKLEDVEHKGLGTPATRAGVIEKLVRSGFVERKKKQLFPTEKGTELIKVMP  539

Query  524  DKFKSAETTSEWEMKLAKISSGEVDKEDFLREIEDSIRELVDRYKN  569
            D +KS   T+EWE +L+ +  GE+  EDF+  I   + ELV  Y+ 
Sbjct  540  DTLKSVKLTAEWEERLGAVERGELSPEDFMAGITAMLTELVKSYQG  585

56) Dtox_2001 in NC_013216


> NC_004668_R1|30|G30|29376814|NP_815968.1|Enterococcus_faecalis_V583|-|30310..32427|topB-2|EF2312|DNA 
topoisomerase III
Length=705

 Score =  389 bits (1462),  Expect = 5e-109, Method: Compositional matrix adjust.
 Identities = 263/626 (43%), Positives = 387/626 (62%), Gaps = 32/626 (5%)

Query  4    LVLAEKPSVAREIARILNCTIKGKGYLEGNKYIVTWALGHLVTLAEPEDYDEKYKTWRTE  63
            LV+AEKPSV+  ++++L    +G GY+EG   +V+W +GHLV LA ++ YD +Y  W   
Sbjct  3    LVIAEKPSVGMALSKVLGAKSRGDGYMEGGGWLVSWCIGHLVELAPADAYDPRYSKWNYA  62

Query  64   DLPMLPAEMKTVVIKKTGPQFHIVSKLMKRPDVRELIIATDAGREGELVARWIMKQARCQ  123
            DLP+LP   +  V+  T  QF+++  L+ R+DV  LI ATDAGREGEL+ R       C 
Sbjct  63   DLPILPKPWQFQVLPDTKKQFEVLKTLIHRADVTALICATDAGREGELIFRLTYHLCGCT  122

Query  124  KPFKRLWISSLTDEAIREGFTRLRPGTEYNNLYDSAICRAEADWLIGLNVTRALTVKYNA  183
            KP KRLWISS+ + AI+ GF  L  G +Y+NLY +A+CRA ADWLIG+N TR +T  Y++
Sbjct  123  KPVKRLWISSMEEAAIQKGFDNLLDGKNYDNLYAAALCRAKADWLIGINGTRLFTTLYQG  182

Query  184  Q-LSAGRVQTPTLAMLVSREKEIKRFVPTDFWTVKANLGKFQAEWRDKSGKHNRFSDCLQ  242
            + L+ GRVQTPTLA+L  RE  I  F    F TV  +L  F+A         +RF+   +
Sbjct  183  KSLNVGRVQTPTLALLAEREAAISGFQKEKFYTVELELEGFRAA-------SERFASKTD  235

Query  243  AETIVNKVKEKSGEVIDLITQEKSEQPPLAYDLTELQRDANKKFGYTAQKTLAGLQMLYE  302
            A  +      K++ V  +  +EK+E+PP  YDLT LQR+AN+ F+YTAQ+TL  LQ LYE
Sbjct  236  AGRLRTGCVGKPATVQTVSQKEKTERPPKLYDLTTLQREANRLFDYTAQQTLDYLQALYE  295

Query  303  RHKLVTYPRTDSRYLTSDMVPTLMPRLKAVSGG--YFAELVKPLTAKPLPINKRLVDNSK  360
            + +L TYPRTDSRYLT DM + L +  ++V+++  + A+L  P+ A       +++DNSK
Sbjct  296  K-RLATYPRTDSRYLTEDMAAGLPALCQSVAAALPFAADLSLPVNA------AQVIDNSK  348

Query  361  VTDHHAIIPTTE--RANLAALTAEEKNIYDLIVRRFIAVFYPAYSYKQTTVIVLIAGEHF  418
            VTDHHAI+PTTE  +++L+AL + EKNI  L+  R++     + +Y +T+V +  +G  F
Sbjct  349  VTDHHAILPTTEAAKTDLSALPSGEKNILFLVAARLLCAVGEPHTYAETAVTLECGGAVF  408

Query  419  HASGKVVTNPGWKAV---YNNESREKDTGYDDTPEQNLPPLKKGDKVKVLSCKSVKGQTK  475
             A GK  T +GW A+   ++   + K    +  P   LP+L KG+K+   +     G T 
Sbjct  409  SAKGKTETAAGWTAMEQAFHATLKKKPK--QPEPSPPLPALTKGQKLTAGGASIKEGATS  466

Query  476  PPARYTEASLLSAMEHPGKFIEDEILK-ESVKESGLGTPATRAEIIEKIISSNYVERRGK  534
            PPA++TE +LLSAMEH++     E+ K E V + GLGTPATRA +IEK++ S +VER+ K
Sbjct  467  PPAHFTEDTLLSAMEHAS---AKEFAKLEDVEHKGLGTPATRAGVIEKLVRSGFVERKKK  523

Query  535  ELIPTAKGIQLVELVPPELKQADLTAKWEQQLHDIAMGKSKRTKFISGIREHAEKIVTT-  593
            +L+PT KG +L+ ++P  LK   LTA WE++L  +  G      F++GI      +V + 
Sbjct  524  QLFPTEKGTELIKVMPDTLKSVKLTAEWEERLGAVERGELSPEDFMAGITAMLTELVKSY  583

Query  594  ---VLNSSSTFKPDNVTGNKCPKCRK  616
                + S++   ++      CP+C K
Sbjct  584  QGVTVASAALSASGRTVIGICPRCGK  609

57) Ccel_0922 in NC_011898


> NC_004668_R1|30|G30|29376814|NP_815968.1|Enterococcus_faecalis_V583|-|30310..32427|topB-2|EF2312|DNA 
topoisomerase III
Length=705

 Score =  377 bits (1419),  Expect = 1e-105, Method: Compositional matrix adjust.
 Identities = 265/651 (41%), Positives = 407/651 (63%), Gaps = 38/651 (5%)

Query  5    LILAEKPSVARDLAKVLNCGQNANGYIMGKKYIVTWALGHLVTLADPEAYGNKYKTWNLE  64
            L++AEKPSV+  L+KVL     ++GY+ G   +V+W +GHLV LA ++AY+ +Y  WN  
Sbjct  3    LVIAEKPSVGMALSKVLGAKSRGDGYMEGGGWLVSWCIGHLVELAPADAYDPRYSKWNYA  62

Query  65   DLPMLPNKMELVVIKQTAKQYGVVRGLLNRADVDELVIATDSGREGELVARWIIMKAGFK  124
            DLP+LP+  ++ V+ +T KQ+ V++ L++RADV  L+ ATD+GREGEL+ R      G  
Sbjct  63   DLPILPKPWQFQVLPDTKKQFEVLKTLIHRADVTALICATDAGREGELIFRLTYHLCGCT  122

Query  125  KPIKRLWISSQTDKAIKEGFAKLRPSKEYDNLYYSAQSRAEADWLIGLNVTRALTCKYNA  184
            KP+KRLWISS  + AI+ GF +L  +K+YDNLY +A  RA ADWLIG+N TR +T  Y++
Sbjct  123  KPVKRLWISSMEEAAIQKGFDNLLDGKNYDNLYAAALCRAKADWLIGINGTRLFTTLYQG  182

Query  185  Q-LSAGRVQTPTLAMIVEREEEIRKFRPKDYWTISAQFNGFTVQWQDSRNNQTRTFNKEE  243
            + L+ GRVQTPTLA++ ERE  I  F+   + T+  +++GF       R    R  +K +
Sbjct  183  KSLNVGRVQTPTLALLAEREAAISGFQKEKFYTVELELEGF-------RAASERFASKTD  235

Query  244  ADGIVAKITGQMGevvevkketkkeLPPLAYDLTELQRDANKKFSYSAKQTLNIMQRLYE  303
            A+ + +   G+ + V  V +  K E PP  YDLT LQR+AN+ F Y+A+QTL+ +Q LYE
Sbjct  236  AGRLRTGCVGKPATVQTVSQKEKTERPPKLYDLTTLQREANRLFDYTAQQTLDYLQALYE  295

Query  304  SHKLVTYPRTDSRYITDDIVPTLNERLKSIAVG-PYAKLVQGVMRNKPSVTKRFVDNSKV  362
              +L TYPRTDSRY+T+D+ + L    +S+A + P+A  +     + P  + + +DNSKV
Sbjct  296  -KRLATYPRTDSRYLTEDMAAGLPALCQSVAAALPFAADL-----SLPVNAAQVIDNSKV  349

Query  363  TDHHAIIPTEQF--VDLFSLNSEERNIYDLIVKRFIAVLSKPFEYEQTTVKLDIAGESFY  420
            TDHHAI+PT +    DL +L S E+NI  L+  R++  ++ P  Y +T+V L+ +G  F 
Sbjct  350  TDHHAILPTTEAAKTDLSALPSGEKNILFLVAARLLCAVGEPHTYAETAVTLECGGAVFS  409

Query  421  AKGKIVKSSGWKTVYDGF-GKL-deddeddndQSLPDIQKGHKAKVVGPKSINGKTKPPA  478
            AKGK   ++GW ++ ++F + L     + +   +LP + KG+K    G+   +G T PPA
Sbjct  410  AKGKTETAAGWTAMEQAFHATLKKKPKQPEPSPPLPALTKGQKLTAGGASIKEGATSPPA  469

Query  479  RYTEATLLSAMEHPG--KFVDNKALKEALESTSGLGTPATRADIIEKLFNTFYIERKGKE  536
            ++TE TLLSAMEH++   F     + +      GLGTPATRA++IEKL  + ++ERK K+
Sbjct  470  HFTEDTLLSAMEHASAKEFAKLEDVEH-----KGLGTPATRAGVIEKLVRSGFVERKKKQ  524

Query  537  IYPTSKGTQLISLVPTDLKSPELTAKWEQQLTLISKGKVNSNVFVNDMKKYARKLV----  592
            ++PT KGT+LI ++P  LKS  LTA WE++L  + +G ++++ F+ ++      LV    
Sbjct  525  LFPTEKGTELIKVMPDTLKSVKLTAEWEERLGAVERGELSPEDFMAGITAMLTELVKSYQ  584

Query  593  GAVIASSEQFKHDNVTREKCPECGKYLLEVNGKKGKMHIC----PDRECGY  639
            G  +AS+     +      CP CGK +  V+GKK+   +C    +   C++
Sbjct  585  GVTVASAALSASGRTVIGICPRCGKNV--VEGKKS--FFCEGWNAAPACDF  631

58) Clo1100_3206 in NC_016791


> NC_004668_R1|30|G30|29376814|NP_815968.1|Enterococcus_faecalis_V583|-|30310..32427|topB-2|EF2312|DNA 
topoisomerase III
Length=705

 Score =  375 bits (1408),  Expect = 8e-105, Method: Compositional matrix adjust.
 Identities = 264/636 (42%), Positives = 404/636 (64%), Gaps = 33/636 (5%)

Query  5    LVIAEKPSVARDLAKVLNCGQNANGYIMGKKYIVTWALGHLVTLADPEAYGNKYKTWNLE  64
            LVIAEKPSV+  L+KVL     ++GY+ G   +V+W +GHLV LA ++AY+ +Y  WN  
Sbjct  3    LVIAEKPSVGMALSKVLGAKSRGDGYMEGGGWLVSWCIGHLVELAPADAYDPRYSKWNYA  62

Query  65   DLPMLPNKMELVVIKQTAKQYGVVRGLLNRADVDELVIATDSGREGELVARWIIMKAGFK  124
            DLP+LP+  ++ V+ +T KQ+ V++ L++RADV  L+ ATD+GREGEL+ R      G  
Sbjct  63   DLPILPKPWQFQVLPDTKKQFEVLKTLIHRADVTALICATDAGREGELIFRLTYHLCGCT  122

Query  125  KPIKRLWISSQTDKAIKEGFAKLRPSKEYDNLYYSAQSRAEADWLVGLNVTRALTCKYNA  184
            KP+KRLWISS  + AI+ GF +L  +K+YDNLY +A  RA ADWL+G+N TR +T  Y++
Sbjct  123  KPVKRLWISSMEEAAIQKGFDNLLDGKNYDNLYAAALCRAKADWLIGINGTRLFTTLYQG  182

Query  185  Q-LSAGRVQTPTLAMIVEREEEIRKFRPKDYWTISAQFNGFSVQWQDGRTNQTRTFNKEE  243
            + L+ GRVQTPTLA++ ERE  I  F+   + T+  +++GF       R+   R  +K +
Sbjct  183  KSLNVGRVQTPTLALLAEREAAISGFQKEKFYTVELELEGF-------RAASERFASKTD  235

Query  244  ADGIVAKITGQIGevvevkketkkeLPPLAYDLTELQRDANKKFSYSAKQTLNIMQRLYE  303
            A+ + +   G+ + V  V +  K E PP  YDLT LQR+AN+ F Y+A+QTL+ +Q LYE
Sbjct  236  AGRLRTGCVGKPATVQTVSQKEKTERPPKLYDLTTLQREANRLFDYTAQQTLDYLQALYE  295

Query  304  SHKLVTYPRTDSRYITDDIVPTLNERLKSIAVG-PY-AKLVQGVMRNKISVTKRFVDNSK  361
              +L TYPRTDSRY+T+D+ + L    +S+A + P+ A L   V   ++      +DNSK
Sbjct  296  -KRLATYPRTDSRYLTEDMAAGLPALCQSVAAALPFAADLSLPVNAAQV------IDNSK  348

Query  362  VTDHHAIIPTEQF--VDLSSLNSEERNIYDLIVKRFIAVLSQPFEYEQTTVKLNVAGESF  419
            VTDHHAI+PT +    DLS+L S E+NI  L+  R++  +++P  Y +T+V L+ +G  F
Sbjct  349  VTDHHAILPTTEAAKTDLSALPSGEKNILFLVAARLLCAVGEPHTYAETAVTLECGGAVF  408

Query  420  YAKGKIVRSSGWKTVYDGF-GKldedsdeddndqslpdIQKGHKAKVVAPKAINGKTKPP  478
             AKGK   ++GW ++ ++F + L   + + +   +LP + KG+K    ++   +G T PP
Sbjct  409  SAKGKTETAAGWTAMEQAFHATLKKKPKQPEPSPPLPALTKGQKLTAGGASIKEGATSPP  468

Query  479  ARYTEATLLSAMEHPG--KFVDNKALKEALESTSGLGTPATRADIIEKLFNTFYIERRGK  536
            A++TE TLLSAMEH++   F     + +      GLGTPATRA++IEKL  + ++ER+ K
Sbjct  469  AHFTEDTLLSAMEHASAKEFAKLEDVEH-----KGLGTPATRAGVIEKLVRSGFVERKKK  523

Query  537  EIYPTSKGTQLISLVPADLKSPELTAKWEQQLSLISKGKANSNAFVGEMKNYAKKLV---  593
            +++PT KGT+LI ++P  LKS  LTA WE++L+ + +G  +++ F++ +      LV   
Sbjct  524  QLFPTEKGTELIKVMPDTLKSVKLTAEWEERLGAVERGELSPEDFMAGITAMLTELVKSY  583

Query  594  -GAVIASSEQFKHDNVTREKCPECGKYLLEVNGKKG  628
             G  +AS+     +      CP CGK +  V+GKK+
Sbjct  584  QGVTVASAALSASGRTVIGICPRCGKNV--VEGKKS  617

59) topB in NC_009725


> NC_004668_R1|30|G30|29376814|NP_815968.1|Enterococcus_faecalis_V583|-|30310..32427|topB-2|EF2312|DNA 
topoisomerase III
Length=705

 Score =  374 bits (1404),  Expect = 2e-104, Method: Compositional matrix adjust.
 Identities = 259/646 (41%), Positives = 417/646 (65%), Gaps = 37/646 (5%)

Query  5    VVLAEKPSVGRDLARVLKCHKKGNGYLEGDRYIVTWALGHLVTLADPEGYGKEFQSWRLE  64
            +V+AEKPSVG  L++VL    +G+GY+EG+  +V+W +GHLV LA +++Y+  +  W   
Sbjct  3    LVIAEKPSVGMALSKVLGAKSRGDGYMEGGGWLVSWCIGHLVELAPADAYDPRYSKWNYA  62

Query  65   DLPIIPEPLKLVVIKKTGKQFNAVKAQLVRKDVTQIVIATDAGREGELVARWIIEKANVR  124
            DLPI+P P ++ V+  T KQF+ +K+ + R DVT ++ ATDAGREGEL+ R   +     
Sbjct  63   DLPILPKPWQFQVLPDTKKQFEVLKTLIHRADVTALICATDAGREGELIFRLTYHLCGCT  122

Query  125  KPIKRLWISSVTDKAIKEGFQKLRSGKEYENLYHSAVARAEADWIVGINATRALTTKFNA  184
            KP+KRLWISS+ + AI+ GF++L  GK+Y+NLY +A+ RA ADW++GIN+TR +TT +++
Sbjct  123  KPVKRLWISSMEEAAIQKGFDNLLDGKNYDNLYAAALCRAKADWLIGINGTRLFTTLYQG  182

Query  185  Q-LSCGRVQTPTLAMIAKREADIQAFKPVPYYGLRAAADQMTLTWQDKKTKQTRTFDQTV  243
            + L+ GRVQTPTLA++A REA I +F+   +Y +     ++ L  ++ ++   R   +T 
Sbjct  183  KSLNVGRVQTPTLALLAEREAAISGFQKEKFYTV-----ELEL--EGFRAASERFASKTD  235

Query  244  TGRLAKDLQGKPAVISELKKTAKKSFAPGLYDLTELQRDAHKRFGFSAKETLSVLQKLYE  303
            +GRL  +  GKPA +  + +  K   +P LYDLT LQR+A++ F+++A++TL  LQ LYE
Sbjct  236  AGRLRTGCVGKPATVQTVSQKEKTERPPKLYDLTTLQREANRLFDYTAQQTLDYLQALYE  295

Query  304  QHKLVTYPRTDSRFLSADIVPTLKDRLNGMEVK-PYAQYVNQILKRGVKAHKGFVNDAKV  362
            + +L TYPRTDSR+L+ D+ + L    +++    P+A      L   V+A +  ++++KV
Sbjct  296  K-RLATYPRTDSRYLTEDMAAGLPALCQSVAAALPFA----ADLSLPVNAAQV-IDNSKV  349

Query  363  SDHHAIIPTEEP--LILSSLSDKERKLYDLIAKRFLAVLMPAFEYEETKVTADIGGETFT  420
            +DHHAI+PT E+    LS+L+  E+++  L+A R+L  +  +  Y ET VT + GG  F+
Sbjct  350  TDHHAILPTTEAAKTDLSALPSGEKNILFLVAARLLCAVGEPHTYAETAVTLECGGAVFS  409

Query  421  AKGKTVQSPGWKAV---YdmyeddddheedkdQTLPDLQQGQRLTVSSLKETSGQTKPPA  477
            AKGKT  ++GW A+   ++        + +    LP L +GQ+LT ++     G T PPA
Sbjct  410  AKGKTETAAGWTAMEQAFHATLKKKPKQPEPSPPLPALTKGQKLTAGGASIKEGATSPPA  469

Query  478  RFNEGTLLSAMENPSAFMQGEEKNLVKTLGETG--GLGTVATRADIIEKLFNSFLIEKKE  535
            +F E+TLLSAME++SA      K++ K L +    GLGT ATRA++IEKL  S ++E+K 
Sbjct  470  HFTEDTLLSAMEHASA------KEFAK-LEDVEHKGLGTPATRAGVIEKLVRSGFVERKK  522

Query  536  KDIFITSKGKQLLQLVPEDLKSPALTAEWEQKLSAIAAGKLKSAVFIKDMKTYAGKTVKE  595
            K++F T KG +L++++P+ LKS  LTAEWE++L+A+  G L +  F+ ++ +     VK 
Sbjct  523  KQLFPTEKGTELIKVMPDTLKSVKLTAEWEERLGAVERGELSPEDFMAGITAMLTELVKS  582

Query  596  IKNSSQTFRHDNISGTA----CPDCGKMMLKVNGKRGTMLVCQDRE  637
             +  + +    + SG +    CP CGK +  V+GK++  + C++++
Sbjct  583  YQGVTVASAALSASGRTVIGICPRCGKNV--VEGKKS--FFCEGWN  624

60) B938_02020 in NC_019842


> NC_004668_R1|30|G30|29376814|NP_815968.1|Enterococcus_faecalis_V583|-|30310..32427|topB-2|EF2312|DNA 
topoisomerase III
Length=705

 Score =  374 bits (1404),  Expect = 2e-104, Method: Compositional matrix adjust.
 Identities = 259/646 (41%), Positives = 417/646 (65%), Gaps = 37/646 (5%)

Query  5    VVLAEKPSVGRDLARVLKCHKKGNGYLEGDRYIVTWALGHLVTLADPEGYGKEFQSWRLE  64
            +V+AEKPSVG  L++VL    +G+GY+EG+  +V+W +GHLV LA +++Y+  +  W   
Sbjct  3    LVIAEKPSVGMALSKVLGAKSRGDGYMEGGGWLVSWCIGHLVELAPADAYDPRYSKWNYA  62

Query  65   DLPIIPEPLKLVVIKKTGKQFNAVKAQLVRKDVTQIVIATDAGREGELVARWIIEKANVR  124
            DLPI+P P ++ V+  T KQF+ +K+ + R DVT ++ ATDAGREGEL+ R   +     
Sbjct  63   DLPILPKPWQFQVLPDTKKQFEVLKTLIHRADVTALICATDAGREGELIFRLTYHLCGCT  122

Query  125  KPIKRLWISSVTDKAIKEGFQKLRSGKEYENLYHSAVARAEADWIVGINATRALTTKFNA  184
            KP+KRLWISS+ + AI+ GF++L  GK+Y+NLY +A+ RA ADW++GIN+TR +TT +++
Sbjct  123  KPVKRLWISSMEEAAIQKGFDNLLDGKNYDNLYAAALCRAKADWLIGINGTRLFTTLYQG  182

Query  185  Q-LSCGRVQTPTLAMIAKREADIQAFKPVPYYGLRAASDQMTLTWQDKKTKQTRTFDQTV  243
            + L+ GRVQTPTLA++A REA I +F+   +Y +     ++ L  ++ ++   R   +T 
Sbjct  183  KSLNVGRVQTPTLALLAEREAAISGFQKEKFYTV-----ELEL--EGFRAASERFASKTD  235

Query  244  TGRLAKDLQGKPAVISELKKTAKKSFAPGLYDLTELQRDAHKRFGFSAKETLSVLQKLYE  303
            +GRL  +  GKPA +  + +  K   +P LYDLT LQR+A++ F+++A++TL  LQ LYE
Sbjct  236  AGRLRTGCVGKPATVQTVSQKEKTERPPKLYDLTTLQREANRLFDYTAQQTLDYLQALYE  295

Query  304  QHKLVTYPRTDSRFLSADIVPTLKDRLNGMEVK-PYAQYVNQILKRGVKAHKGFVNDAKV  362
            + +L TYPRTDSR+L+ D+ + L    +++    P+A      L   V+A +  ++++KV
Sbjct  296  K-RLATYPRTDSRYLTEDMAAGLPALCQSVAAALPFA----ADLSLPVNAAQV-IDNSKV  349

Query  363  SDHHAIIPTEEP--LILSSLSDKERKLYDLIAKRFLAVLMPAFEYEETKVTADIGGETFT  420
            +DHHAI+PT E+    LS+L+  E+++  L+A R+L  +  +  Y ET VT + GG  F+
Sbjct  350  TDHHAILPTTEAAKTDLSALPSGEKNILFLVAARLLCAVGEPHTYAETAVTLECGGAVFS  409

Query  421  AKGKTVQSPGWKAV---YdmyeddddheedkdQTLPDLQQGQRLTVSSLKETSGQTKPPA  477
            AKGKT  ++GW A+   ++        + +    LP L +GQ+LT ++     G T PPA
Sbjct  410  AKGKTETAAGWTAMEQAFHATLKKKPKQPEPSPPLPALTKGQKLTAGGASIKEGATSPPA  469

Query  478  RFNEGTLLSAMENPSAFMQGEEKNLVKTLGETG--GLGTVATRADIIEKLFNSFLIEKKE  535
            +F E+TLLSAME++SA      K++ K L +    GLGT ATRA++IEKL  S ++E+K 
Sbjct  470  HFTEDTLLSAMEHASA------KEFAK-LEDVEHKGLGTPATRAGVIEKLVRSGFVERKK  522

Query  536  KDIFITSKGKQLLQLVPEDLKSPALTAEWEQKLSAIAAGKLKSAVFIKDMKTYAGKTVKE  595
            K++F T KG +L++++P+ LKS  LTAEWE++L+A+  G L +  F+ ++ +     VK 
Sbjct  523  KQLFPTEKGTELIKVMPDTLKSVKLTAEWEERLGAVERGELSPEDFMAGITAMLTELVKS  582

Query  596  IKNSSQTFRHDNISGTA----CPDCGKMMLKVNGKRGTMLVCQDRE  637
             +  + +    + SG +    CP CGK +  V+GK++  + C++++
Sbjct  583  YQGVTVASAALSASGRTVIGICPRCGKNV--VEGKKS--FFCEGWN  624

61) SpiBuddy_1109 in NC_015152


> NC_004668_R1|30|G30|29376814|NP_815968.1|Enterococcus_faecalis_V583|-|30310..32427|topB-2|EF2312|DNA 
topoisomerase III
Length=705

 Score =  373 bits (1403),  Expect = 2e-104, Method: Compositional matrix adjust.
 Identities = 258/641 (41%), Positives = 407/641 (64%), Gaps = 29/641 (4%)

Query  3    KLVLAEKPSVGRELARVLNCYKRETGYIEGEHYIVTWALGHLVELAQPAAYSERYKRWSL  62
            +LV+AEKPSVG  L++VL    R  GY+EG   +V+W +GHLVELA + AY  RY +W+ 
Sbjct  2    QLVIAEKPSVGMALSKVLGAKSRGDGYMEGGGWLVSWCIGHLVELAPADAYDPRYSKWNY  61

Query  63   RDLPMLPPVLQQEVIEQSKDQFAVVKSLIKRPDIESLVIATDAGREGELVARWIMKLADY  122
             DLP+LP   Q +V+ ++K QF V+K+LI R+D+ +L+ ATDAGREGEL+ R    L + 
Sbjct  62   ADLPILPKPWQFQVLPDTKKQFEVLKTLIHRADVTALICATDAGREGELIFRLTYHLCGC  121

Query  123  QGPAHRLWISSQTEGAIKEGFANLKEASLYDNLYKAAESRAAADWYVGMNVTRALTCHYD  182
              P  RLWISS  E+AI+ GF NL ++  YDNLY AA  RA ADW +G+N TR +T  Y+
Sbjct  122  TKPVKRLWISSMEEAAIQKGFDNLLDGKNYDNLYAAALCRAKADWLIGINGTRLFTTLYQ  181

Query  183  AK-LSAGRVQTPTLALMTRREDEIEAFSGQFYWTLKADFIHFSASYYPTEDTIRITEEAT  241
            +K L+ GRVQTPTLAL++ RE  I +F  + + T+  ++  F A+      + R++  + 
Sbjct  182  GKSLNVGRVQTPTLALLAEREAAISGFQKEKFYTVELELEGFRAA------SERFASKTD  235

Query  242  AKALEASLVGKQGRVVSLETVQRNEQPPLAYDLTELQRDANNLLDFSAKQTLDVLQALYE  301
            A  L ++ VGK + V ++   ++ E+PP  YDLT LQR+AN L+D++A+QTLD LQALYE
Sbjct  236  AGRLRTGCVGKPATVQTVSQKEKTERPPKLYDLTTLQREANRLFDYTAQQTLDYLQALYE  295

Query  302  QHKIVTYPRTDSRYITTDIVATLPDRLRSLADTPFAPLCSGFVKD-GFRVDEERFVQDLQ  360
            + ++ TYPRTDSRY+T D+ A LP    +L ++  A+L   F  D ++ V+  + +++ +
Sbjct  296  K-RLATYPRTDSRYLTEDMAAGLP----ALCQSVAAAL--PFAADLSLPVNAAQVIDNSK  348

Query  361  VTDHHAIIPTEQ--RVNLSRLNAQEKALWELIVLRFLEVLSPDYIYQTTTLIAEVEESRF  418
            VTDHHAI+PT +  + +LS L + EK +  L+  R+L  ++    Y  T++  E   + F
Sbjct  349  VTDHHAILPTTEAAKTDLSALPSGEKNILFLVAARLLCAVGEPHTYAETAVTLECGGAVF  408

Query  419  KTRLTIPVQQGWRSVATLIGKRSAQASLGEEDEASPALLSLKQGDGLTISSLKLRKLATT  478
             ++       GW ++   +  +++      + E+SP+L +L +G+ LT ++  ++  AT+
Sbjct  409  SAKGKTETAAGWTAMEQAF--HATLKKKPKQPEPSPPLPALTKGQKLTAGGASIKEGATS  466

Query  479  APSRYTEATLLSAMEHAGRFVDDAKLKKRLSNGLGTPATRADIIEKLIQNHYIERAGKEL  538
            +P+++TE TLLSAMEHA+   + AKL     +GLGTPATRA++IEKL+++ ++ER  K+L
Sbjct  467  PPAHFTEDTLLSAMEHASA-KEFAKLEDVEHKGLGTPATRAGVIEKLVRSGFVERKKKQL  525

Query  539  VPTPKGRELVRLAPEELRSPELTGRWEERLGNIAEGKENGDLFIQDIKRNASALVTQVTG  598
             PT KG EL+++ P+ L+S  LT+ WEERLG +  G  + + F+ +I    + LV    G
Sbjct  526  FPTEKGTELIKVMPDTLKSVKLTAEWEERLGAVERGELSPEDFMAGITAMLTELVKSYQG  585

Query  599  SSDVFSPHFPDAKQ----CPYCKTPMMKVVDEIGQNHYLCQ  635
             +   ++  + ++     CP C     +VV+  G++ ++C+
Sbjct  586  VTVASAALSASGRTVIGICPRCG---KNVVE--GKKSFFCE  621

62) Desku_2425 in NC_015573


> NC_004668_R1|30|G30|29376814|NP_815968.1|Enterococcus_faecalis_V583|-|30310..32427|topB-2|EF2312|DNA 
topoisomerase III
Length=705

 Score =  372 bits (1398),  Expect = 6e-104, Method: Compositional matrix adjust.
 Identities = 290/722 (41%), Positives = 436/722 (61%), Gaps = 45/722 (6%)

Query  3    KLVIAEKPSVARDIASALGKFAQKDGYLENDRLVISWALGHLLELADAHEYDPAFVKWTL  62
            +LVIAEKPSV+  ++  LG  ++ DGY+E +  ++SW +GHL+ELA A+ YDP + KW  
Sbjct  2    QLVIAEKPSVGMALSKVLGAKSRGDGYMEGGGWLVSWCIGHLVELAPADAYDPRYSKWNY  61

Query  63   EPLPIIPEEFKLHPIRSGAKQLKILKQLLNSADVAEVINACDAGREGELIFRRIYEWCGC  122
              LPI+P   +++ +    KQ+ +LK L++ ADV+ +I A DAGREGELIFR  Y+ CGC
Sbjct  62   ADLPILPKPWQFQVLPDTKKQFEVLKTLIHRADVTALICATDAGREGELIFRLTYHLCGC  121

Query  123  RKPVKRLWLSEATPSAIREAFKKLRDGRELDNLaaaararaeaDWIVGINATRAFSVK-H  181
             KPVKRLW+S    +AI+ +F +L DG++ DNL AAA  RA ADW++GIN+TR F+   +
Sbjct  122  TKPVKRLWISSMEEAAIQKGFDNLLDGKNYDNLYAAALCRAKADWLIGINGTRLFTTLYQ  181

Query  182  KTLLSVGRVQTPTLALVVQREREIRDFKPETYWEVRATFQKSGGATYRGRWFRGGESRIK  241
               L+VGRVQTPTLAL+ +RE  I +F+ E +  V   ++           FR++  R+ 
Sbjct  182  GKSLNVGRVQTPTLALLAEREAAISGFQKEKFYTVELELEG----------FRAASERFA  231

Query  242  EKSraeelvraalaaGSGRVAQVEKRTKTEAPPLLFNLNDLQKEANRKYGMTAQKVLDAA  301
             K+ A  L  + ++  ++ V  V ++ KTE PP L++L  LQ+EANR ++ TAQ+ LD  
Sbjct  232  SKTDAGRLRTGCVGK-PATVQTVSQKEKTERPPKLYDLTTLQREANRLFDYTAQQTLDYL  290

Query  302  QALYEKHKLITYPRTDSRHLTEALARDTLQKRLAALEKCPEYGELIRRIRPGMLP--GKR  359
            QALYEK +L TYPRTDSR LTE +A +     L+AL  C   +  +       LP  + +
Sbjct  291  QALYEK-RLATYPRTDSRYLTEDMAAG-----LPAL--CQSVAAALPFAADLSLPVNAAQ  342

Query  360  YIDDAGVTDHHAIIPT--DVTPDPSALNPAERQVYDLVVRRFLAMFYPPAVYDETAVVTE  417
             ID++ VTDHHAI+PT      D SAL ++E+++  LV  R+L     P  Y ETAV  E
Sbjct  343  VIDNSKVTDHHAILPTTEAAKTDLSALPSGEKNILFLVAARLLCAVGEPHTYAETAVTLE  402

Query  418  VGDETFISRGRVEIEPGWKAVYGPeekeekdgkdedgeSQPLPPLaegetvgveeagave  477
             G+  F ++G+ E  +GW A+  + +   K    +   S PLP+L+ G+ +    A+  E
Sbjct  403  CGGAVFSAKGKTETAAGWTAMEQAFHATLKKKPKQPEPSPPLPALTKGQKLTAGGASIKE  462

Query  478  RQTKPPKRYTEATLLAAMENAGRLLDDREMAETLKAAG--GIGTPATRAAIIETLIKRGY  535
              T PP ++TE TLL+AME+A+     +E A  L      G+GTPATRA++IE L++ G+
Sbjct  463  GATSPPAHFTEDTLLSAMEHAS----AKEFA-KLEDVEHKGLGTPATRAGVIEKLVRSGF  517

Query  536  IERRKKTLVPTPRGEALIDLVPEKLKSVELTAQWEDGLRRIEEGLDDARLWLVGLKNFTV  595
            +ER+KK L PT +G  LI ++P+ LKSV LTA+WE+ L  +E G   +   + G+     
Sbjct  518  VERKKKQLFPTEKGTELIKVMPDTLKSVKLTAEWEERLGAVERGELSPEDFMAGITAMLT  577

Query  596  EVVAMAKEQEANGA---VHQKEVMGRCPLCGRDVLEYTKSYGCSGYRD--GCNFAIWKE-  649
            E+V   +     +A      + V+G CP CG++V+E  KS+ C G     +C+FA+WK+ 
Sbjct  578  ELVKSYQGVTVASAALSASGRTVIGICPRCGKNVVEGKKSFFCEGWNAAPACDFALWKND  637

Query  650  ----TAGKKITAKQARELLQKGRTGVIKGFKSKAGKSFDAILTLGEDG----KVNFEFAD  701
                +  K +T K A  LL+KGR ++   F  K G  +DAI+ + + G    + ++EF +
Sbjct  638  RFFTSKHKELTRKAAAALLKKGRVAMTGLFSEKKGVLYDAIVVMEDTGEKFVRFKLEFDN  697

Query  702  HA  703
            ++
Sbjct  698  NT  699


 Score = 63.1 bits (220),  Expect = 7e-11, Method: Compositional matrix adjust.
 Identities = 33/97 (35%), Positives = 56/97 (58%), Gaps = 13/97 (13%)

Query  706  ALGKCPLCGKDVIEGKKGYGCAGWKE--GCKFVIWKE-----IAGKKIAANLAKELLQKG  758
             +G CP CGK+V+EGKK++ C GW+   +C F +WK+        K ++ + A  LL+KG
Sbjct  600  VIGICPRCGKNVVEGKKSFFCEGWNAAPACDFALWKNDRFFTSKHKELTRKAAAALLKKG  659

Query  759  RTGVIKGFKSRAGKDFEAALVLGEGG------KIEFE  789
            R ++   F  + G  ++A +V+ + G      K+EF+
Sbjct  660  RVAMTGLFSEKKGVLYDAIVVMEDTGEKFVRFKLEFD  696

63) FPR_19060 in NC_021020


> NC_004668_R1|30|G30|29376814|NP_815968.1|Enterococcus_faecalis_V583|-|30310..32427|topB-2|EF2312|DNA 
topoisomerase III
Length=705

 Score =  363 bits (1364),  Expect = 2e-101, Method: Compositional matrix adjust.
 Identities = 251/543 (47%), Positives = 356/543 (66%), Gaps = 29/543 (5%)

Query  1    MVGINASRLFSCLYN-QPLAVGRVMTPVLAMTVVREAAIAAFTPEKFYTVDLELTSGCTA  59
            ++GIN++RLF+ LY+ ++L VGRV TP LA+   REAAI++F  EKFYTV+LEL  G  A
Sbjct  167  LIGINGTRLFTTLYQGKSLNVGRVQTPTLALLAEREAAISGFQKEKFYTVELEL-EGFRA  225

Query  60   SSRRIPEKSVAENLLKACRKEMVATIQRITRKEKSENPPPLYDLTTLQRDANRLLGYSAQ  119
            +S R++ K+ A  L  +C     AT+Q +++KEK+E PP LYDLTTLQR+ANRL++Y+AQ
Sbjct  226  ASERFASKTDAGRLRTGC-VGKPATVQTVSQKEKTERPPKLYDLTTLQREANRLFDYTAQ  284

Query  120  QTLDYVQSLYEKKLTTYPRTDSCYITdddeemleelteelegfldITSADVDEAVPRTRR  179
            QTLDY+Q+LYEK+L+TYPRTDS Y+T+D    L  L + + + L + +AD+  +V  + +
Sbjct  285  QTLDYLQALYEKRLATYPRTDSRYLTEDMAAGLPALCQSVAAALPF-AADLSLPV-NAAQ  342

Query  180  TVNREKVTDHHAILPTRSMLQADLDALPKGEQNVLKLIIARTLMAVSKPFRYLETLLTTE  239
             ++  KVTDHHAILPT    ++DL ALP GE+N+L L+ AR L AV+ P  Y ET +T E
Sbjct  343  VIDNSKVTDHHAILPTTEAAKTDLSALPSGEKNILFLVAARLLCAVGEPHTYAETAVTLE  402

Query  240  CAGEEFTAKGKEILEEGWKAVERKVLADILNRKQE-------LTALPNAAENEYGILNAE  292
            C+G  F+AKGK     GW A+E+  +   L++K         L AL ++     G   A 
Sbjct  403  CGGAVFSAKGKTETAAGWTAMEQ-AFHATLKKKPKQPEPSPPLPALTKGQKLTAG--GAS  459

Query  293  LKEGQTSPPKHFTEDTLLHAMETASADSMP--EGVERQGIGTPATRAATIEKLVQKGFLE  350
            +KEG TSPP HFTEDTLL AME ASA   +  E+VE++G+GTPATRA+ IEKLV+ GF+E
Sbjct  460  IKEGATSPPAHFTEDTLLSAMEHASAKEFAKLEDVEHKGLGTPATRAGVIEKLVRSGFVE  519

Query  351  RKGTKKTKVLLPTDKGKALITVMPEEIQSADMTADWEAKLLQIERSEMEPETFMTEIKEM  410
            R    K K L+PT+KG  LI VMP+ ++S  +TA+WE +L  +ER+E+ PE FM+ I  M
Sbjct  520  R----KKKQLFPTEKGTELIKVMPDTLKSVKLTAEWEERLGAVERGELSPEDFMAGITAM  575

Query  411  ISSLVTTTEAAKGANALMKN---KIIGVCPNCGANVVEREKGWFCES----NPCRFVLWK  463
            ++ LV + ++   A+A +      +IG+CP CG NVVE  K+ FCE+     +C F LWK
Sbjct  576  LTELVKSYQGVTVASAALSASGRTVIGICPRCGKNVVEGKKSFFCEGWNAAPACDFALWK  635

Query  464  DNAFFKRLGKRLDGRMADKLLRDGHVRLKD-CKSAKGKTYNATVLLSTEPDGRSKFSLEF  522
            ++ FF    K L  + A  LL+ G+V + +     KG  Y+A V++    +   +F LEF
Sbjct  636  NDRFFTSKHKELTRKAAAALLKKGRVAMTGLFSEKKGVLYDAIVVMEDTGEKFVRFKLEF  695

Query  523  EGG  525
            +  
Sbjct  696  DNN  698