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Homologs of Spaf_1839 gene of NC_017905_P3

protein-level

Hit (GenBank Accn)

Product

Source Genome

Eval.

Ident.(%)

1) Spaf_1839
( YP_006310605.1 )

immunogenic secreted protein

NC_017905
(Streptococcus parasanguinis FW213)

7e-157

100

2) HMPREF0833_11837
( YP_004622796.1 )

immunogenic secreted protein

NC_015678
(Streptococcus parasanguinis ATCC 15912)

2e-155

3) isp2
( YP_006858926.1 )

transfer protein

NC_018712
(Streptococcus dysgalactiae RE378)

6e-132

4) SDE12394_03105
( YP_006012726.1 )

immunogenic secreted protein, putative

NC_017567
(Streptococcus dysgalactiae ATCC 12394)

4e-109

5) SeseC_00436
( YP_006042276.1 )

amidase

NC_017582
(Streptococcus equi ATCC 35246)

1e-82

• Sequence Alignments

1) Spaf_1839 in NC_017905


> NC_017905_P3|3|G3|387880302|YP_006310605.1|Streptococcus_parasanguinis_FW213|-|1415..2527|-|Spaf_1839|immunogenic 
secreted 
protein
Length=370

 Score =  546 bits (2062),  Expect = 7e-157, Method: Compositional matrix adjust.
 Identities = 370/370 (100%), Positives = 370/370 (100%), Gaps = 0/370 (0%)

Query  1    MKKLKWYLLAGliplflpvliiiilMGAVGGGGTNGSPQSQNGVTYADHWSDGDPYTHNL  60
            MKKLKWYLLAGLIPLFLPVLIIIILMGAVGGGGTNGSPQSQNGVTYADHWSDGDPYTHNL
Sbjct  1    MKKLKWYLLAGLIPLFLPVLIIIILMGAVGGGGTNGSPQSQNGVTYADHWSDGDPYTHNL  60

Query  61   LVHRFGITAEQLDGFLDTLGISYDKTRINGKKLLEWEAKSNLDVRGIVAIALNESSLGTA  120
            LVHRFGITAEQLDGFLDTLGISYDKTRINGKKLLEWEAKSNLDVRGIVAIALNESSLGTA
Sbjct  61   LVHRFGITAEQLDGFLDTLGISYDKTRINGKKLLEWEAKSNLDVRGIVAIALNESSLGTA  120

Query  121  GVATNPGANMFGFGAYDSNPEYANNFNDEIAVVGLTQQTIIGNKNQTFKIQDDKAKKFAN  180
            GVATNPGANMFGFGAYDSNPEYANNFNDEIAVVGLTQQTIIGNKNQTFKIQDDKAKKFAN
Sbjct  121  GVATNPGANMFGFGAYDSNPEYANNFNDEIAVVGLTQQTIIGNKNQTFKIQDDKAKKFAN  180

Query  181  GTLNPATDGGVYFTDTTGSGKRRAETMQKLDTFIDEHGGTPKAPEQTTGKTRDGGGITSN  240
            GTLNPATDGGVYFTDTTGSGKRRAETMQKLDTFIDEHGGTPKAPEQTTGKTRDGGGITSN
Sbjct  181  GTLNPATDGGVYFTDTTGSGKRRAETMQKLDTFIDEHGGTPKAPEQTTGKTRDGGGITSN  240

Query  241  DIPVGYSLTTAIDTTGYITSTYPWGQCTWYVFNRGKQVGVNFDPFMGNGGQWMNKPGFIT  300
            DIPVGYSLTTAIDTTGYITSTYPWGQCTWYVFNRGKQVGVNFDPFMGNGGQWMNKPGFIT
Sbjct  241  DIPVGYSLTTAIDTTGYITSTYPWGQCTWYVFNRGKQVGVNFDPFMGNGGQWMNKPGFIT  300

Query  301  THTPTEHSALSFSPGQAGADPIYGHISFVEQVKSDGSILVSECNVKGLGIISYRTFDAET  360
            THTPTEHSALSFSPGQAGADPIYGHISFVEQVKSDGSILVSECNVKGLGIISYRTFDAET
Sbjct  301  THTPTEHSALSFSPGQAGADPIYGHISFVEQVKSDGSILVSECNVKGLGIISYRTFDAET  360

Query  361  AKQFTYVIGH  370
            AKQFTYVIGH
Sbjct  361  AKQFTYVIGH  370

2) HMPREF0833_11837 in NC_015678


> NC_017905_P3|3|G3|387880302|YP_006310605.1|Streptococcus_parasanguinis_FW213|-|1415..2527|-|Spaf_1839|immunogenic 
secreted 
protein
Length=370

 Score =  542 bits (2045),  Expect = 2e-155, Method: Compositional matrix adjust.
 Identities = 364/370 (99%), Positives = 367/370 (99%), Gaps = 0/370 (0%)

Query  1    MKKLKWFLLAGliplflpvliiiilMGAVGGGGTNGSPQSQNGVTYADHWSDGDPYTHNL  60
            MKKLKW+LLAGLIPLFLPVLIIIILMGAVGGGGTNGSPQSQNGVTYADHWSDGDPYTHNL
Sbjct  1    MKKLKWYLLAGLIPLFLPVLIIIILMGAVGGGGTNGSPQSQNGVTYADHWSDGDPYTHNL  60

Query  61   LVHRFGITAEQLDGFLDTLGISYDKNRINGKKLLEWEAKSNLDVRGIVAIALNESSLGTA  120
            LVHRFGITAEQLDGFLDTLGISYDK RINGKKLLEWEAKSNLDVRGIVAIALNESSLGTA
Sbjct  61   LVHRFGITAEQLDGFLDTLGISYDKTRINGKKLLEWEAKSNLDVRGIVAIALNESSLGTA  120

Query  121  GVATNPGANMFGFGAYDSNPEYANNFNDEIAVVELTQQTIIGNKNQTFKIQDDKAKKFAN  180
            GVATNPGANMFGFGAYDSNPEYANNFNDEIAVV LTQQTIIGNKNQTFKIQDDKAKKFAN
Sbjct  121  GVATNPGANMFGFGAYDSNPEYANNFNDEIAVVGLTQQTIIGNKNQTFKIQDDKAKKFAN  180

Query  181  GTLNPATDGGVYFTDTTGSGKRRAETMQKLDAFIDEHGGTPKAPEQTTGKTRDGGGVTSN  240
            GTLNPATDGGVYFTDTTGSGKRRAETMQKLD+FIDEHGGTPKAPEQTTGKTRDGGG+TSN
Sbjct  181  GTLNPATDGGVYFTDTTGSGKRRAETMQKLDTFIDEHGGTPKAPEQTTGKTRDGGGITSN  240

Query  241  DIPVGYSLTTAIDTTGYITSTYPWGQCTWYVFNRGKQVGVNFDPFMGNGGQWMNKPGFTT  300
            DIPVGYSLTTAIDTTGYITSTYPWGQCTWYVFNRGKQVGVNFDPFMGNGGQWMNKPGF T
Sbjct  241  DIPVGYSLTTAIDTTGYITSTYPWGQCTWYVFNRGKQVGVNFDPFMGNGGQWMNKPGFIT  300

Query  301  THTPTEHSALSFSPGQAGADPIYGHISFVEQVKSDGSILVSECNVKGLGIISYRTFDAET  360
            THTPTEHSALSFSPGQAGADPIYGHISFVEQVKSDGSILVSECNVKGLGIISYRTFDAET
Sbjct  301  THTPTEHSALSFSPGQAGADPIYGHISFVEQVKSDGSILVSECNVKGLGIISYRTFDAET  360

Query  361  AKQFTYVIGH  370
            AKQFTYVIGH
Sbjct  361  AKQFTYVIGH  370

3) isp2 in NC_018712


> NC_017905_P3|3|G3|387880302|YP_006310605.1|Streptococcus_parasanguinis_FW213|-|1415..2527|-|Spaf_1839|immunogenic 
secreted 
protein
Length=370

 Score =  464 bits (1747),  Expect = 6e-132, Method: Compositional matrix adjust.
 Identities = 277/330 (84%), Positives = 311/330 (95%), Gaps = 0/330 (0%)

Query  61   QNEVTYSEHWSDGDAYTHNLLVHRYGIKASQLDGFLKTLGIDYDSSRINGTKLLEWEAKS  120
            QN VTY++HWSDGD+YTHNLLVHR+GI A QLDGFL TLGI YD +RING KLLEWEAKS
Sbjct  41   QNGVTYADHWSDGDPYTHNLLVHRFGITAEQLDGFLDTLGISYDKTRINGKKLLEWEAKS  100

Query  121  NLDVRAILAIALNESSLGTAGVATNPGANMFGYGAFDSNPENANNFNDEVAVVALTQQTI  180
            NLDVR+I+AIALNESSLGTAGVATNPGANMFG+GA+DSNPE ANNFNDE+AVV+LTQQTI
Sbjct  101  NLDVRGIVAIALNESSLGTAGVATNPGANMFGFGAYDSNPEYANNFNDEIAVVGLTQQTI  160

Query  181  IGNKNQTFKIQDDKAKKLASGTLNTAVDGGVYFTDTSGSGKRRAETMQKLDTYIDENGGT  240
            IGNKNQTFKIQDDKAKK+A+GTLN A DGGVYFTDT+GSGKRRAETMQKLDT+IDE+GGT
Sbjct  161  IGNKNQTFKIQDDKAKKFANGTLNPATDGGVYFTDTTGSGKRRAETMQKLDTFIDEHGGT  220

Query  241  PKAPKQTTGKSRDGGGVTSSDIPEGYSLTQAIDTTNYIASSYPWGQCTWFVYNRGKEVGV  300
            PKAP QTTGK+RDGGG+TS+DIP GYSLT AIDTT YI+S+YPWGQCTW+V+NRGK+VGV
Sbjct  221  PKAPEQTTGKTRDGGGITSNDIPVGYSLTTAIDTTGYITSTYPWGQCTWYVFNRGKQVGV  280

Query  301  NFDPYMGNGNQWMEKPGYTTTNTPTEHSALSFSSSQAGADPVYGHVAFVEQVKSDGSILI  360
            NFDP+MGNG QWM+KPG+ TT+TPTEHSALSFS++QAGADP+YGH++FVEQVKSDGSIL+
Sbjct  281  NFDPFMGNGGQWMNKPGFITTHTPTEHSALSFSPGQAGADPIYGHISFVEQVKSDGSILV  340

Query  361  SESNYKGLGIISYRTFDAETAKQFTYVIGK  390
            SE N KGLGIISYRTFDAETAKQFTYVIG 
Sbjct  341  SECNVKGLGIISYRTFDAETAKQFTYVIGH  370

4) SDE12394_03105 in NC_017567


> NC_017905_P3|3|G3|387880302|YP_006310605.1|Streptococcus_parasanguinis_FW213|-|1415..2527|-|Spaf_1839|immunogenic 
secreted 
protein
Length=370

 Score =  388 bits (1458),  Expect = 4e-109, Method: Compositional matrix adjust.
 Identities = 243/369 (66%), Positives = 317/369 (86%), Gaps = 4/369 (1%)

Query  1    MKWFVKRFGCLTLLLAPILMVLFLFIgagstsnsgsattLDGVQYVDHWSNGDAYTHNIL  60
            +KW++  ++ L  L+ P+L++++L  + G+ + +GS+ + +GV Y DHWS+GD+YTHN+L
Sbjct  4    LKWYL--LAGLIPLFLPVLIIIILMGAVGGGGTNGSPQSQNGVTYADHWSDGDPYTHNLL  61

Query  61   MHRYGITAEQLDGFLDSTGIAYDKTRINGKKLLEWSNKSGLDVRAIVAIAQMESSFGTAG  120
            +HR+GITAEQLDGFLD+ GI+YDKTRINGKKLLEW  KS LDVR+IVAIA  ESS+GTAG
Sbjct  62   VHRFGITAEQLDGFLDTLGISYDKTRINGKKLLEWEAKSNLDVRGIVAIALNESSLGTAG  121

Query  121  VATKPGANMFGYGAFdsnsdnasnyndETAVVALTRVSIINNRNETFKIQDEKAQKNAKG  180
            VAT+PGANMFG+GA+DSN++ A+N+NDE AVV+LT+ +II N+N+TFKIQD+KA+K A+G
Sbjct  122  VATNPGANMFGFGAYDSNPEYANNFNDEIAVVGLTQQTIIGNKNQTFKIQDDKAKKFANG  181

Query  181  TLNVAKDGGVYFTDTSGSGKRRAEVMEKLDKWIDEHGGTPEPPKtsgsrtgg--gvtsgD  238
            TLN A DGGVYFTDT+GSGKRRAE M+KLD  IDEHGGTP +P  + ++T +  G+TS D
Sbjct  182  TLNPATDGGVYFTDTTGSGKRRAETMQKLDTFIDEHGGTPKAPEQTTGKTRDGGGITSND  241

Query  239  IPAGYSLTKAIDSSSYITSSYPWGQCTWFVWNRGRELGITFDPYMGNGGDWKYKPGYQTT  298
            IP GYSLT AID+++YITS+YPWGQCTW+V NRG+++G+ FDP+MGNGG+W  KPG+ TT
Sbjct  242  IPVGYSLTTAIDTTGYITSTYPWGQCTWYVFNRGKQVGVNFDPFMGNGGQWMNKPGFITT  301

Query  299  RTPTEHSAICFSPGEGGSHPYYGHIAFVEQVKPDGSILISESNAQGLGVISYRVFDAQTA  358
            +TPTEHSA+ FSPG++G++P YGHI+FVEQVK+DGSIL+SE N +GLG+ISYR FDA+TA
Sbjct  302  HTPTEHSALSFSPGQAGADPIYGHISFVEQVKSDGSILVSECNVKGLGIISYRTFDAETA  361

Query  359  KQFTYVIGK  367
            KQFTYVIG 
Sbjct  362  KQFTYVIGH  370

5) SeseC_00436 in NC_017582


> NC_017905_P3|3|G3|387880302|YP_006310605.1|Streptococcus_parasanguinis_FW213|-|1415..2527|-|Spaf_1839|immunogenic 
secreted 
protein
Length=370

 Score =  300 bits (1125),  Expect = 1e-82, Method: Compositional matrix adjust.
 Identities = 183/326 (57%), Positives = 248/326 (77%), Gaps = 4/326 (1%)

Query  138  AYVAHWSGQSAYTHNLLSRRYGIKAEQLDSFLKSTKIKYDEKRINGAALLQWEKKSGLDV  197
            +Y  HWS+  +YTHNLL +R+GI AEQLD+FL +  I YD  RING  LL+WE KS LDV
Sbjct  45   TYADHWSDGDPYTHNLLVHRFGITAEQLDGFLDTLGISYDKTRINGKKLLEWEAKSNLDV  104

Query  198  RAIVAIAMTESELGTKGNATLLGSNMFGYALFDLDSKKPNQFNDELAIVKLTQETIIKNS  257
            R+IVAIA+ ES LGT G AT  G+NMFG++ +D ++  +N+FNDE+A+V LTQ+TII N 
Sbjct  105  RGIVAIALNESSLGTAGVATNPGANMFGFGAYDSNPEYANNFNDEIAVVGLTQQTIIGNK  164

Query  258  NLSFEqqdqkadkfakkqLNFASDGGLYFTDTNGIGKHRAEIMEKLDAWIDQHGGTPEIP  317
            N +F  QD+KA KFA+  LN A+DGG+YFTDT G GK+RAE M+KLD+ ID+HGGTP  P
Sbjct  165  NQTFKIQDDKAKKFANGTLNPATDGGVYFTDTTGSGKRRAETMQKLDTFIDEHGGTPKAP  224

Query  318  AEL--KIQSSSSFAV--VPTGYKLSKSYDILSYQASSYAWGQCTWYVYNRAKELGYQFDS  373
             +   K + +++++   +P GY L+ + D  +Y +S+Y+WGQCTWYV+NR+K++G +FD+
Sbjct  225  EQTTGKTRDGGGITSNDIPVGYSLTTAIDTTGYITSTYPWGQCTWYVFNRGKQVGVNFDP  284

Query  374  FMGNGGDWRFKSGYSISKEPKVGYAVSFAPGQAGADGLYGHVSIVEDVRKDGSILISESN  433
            FMGNGG+W  K+G+  +  P    A+SF+PGQAGAD +YGH+S+VE+V+ DGSIL+SE N
Sbjct  285  FMGNGGQWMNKPGFITTHTPTEHSALSFSPGQAGADPIYGHISFVEQVKSDGSILVSECN  344

Query  434  CLGLGQISYRTFTAEQANQLTYVVGK  459
              GLG ISYRTF AE A+Q+TYV+G 
Sbjct  345  VKGLGIISYRTFDAETAKQFTYVIGH  370