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PAthogenisity Island DataBase (PAI DB)

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Homologs of HP0521B gene of AY330640

protein-level

Hit (GenBank Accn)

Product

Source Genome

Eval.

Ident.(%)

1) HPB14_04040
( YP_006219523.1 )

HP0521B-like protein

NC_017733
(Helicobacter pylori HUP-B14)

1e-101

2) cag2
( YP_003728745.1 )

cag pathogenicity island protein epsilon

NC_014256
(Helicobacter pylori B8)

4e-95

3) HPAG1_0496
( YP_627237.1 )

HP0521B-like protein

NC_008086
(Helicobacter pylori HPAG1)

5e-92

• Sequence Alignments

1) HPB14_04040 in NC_017733


> AY330640|2|G2|37811845|AAR03913.1|Helicobacter_pylori_Du52:2|+|562..1299|-|HP0521B|HP0521B 
protein
Length=245

 Score =  361 bits (1358),  Expect = 1e-101, Method: Compositional matrix adjust.
 Identities = 226/243 (94%), Positives = 235/243 (97%), Gaps = 0/243 (0%)

Query  6    MRENFKNLGVLVVYYSLHDPHKRPINSFSLKTSNIIGFSIFICEHAQKEIMQKVASRHTD  65
            MRENFKNLGV+VVYYSLHD HK+PINSFSLKTSNIIGFSIFICEHAQKEIMQKVASRHTD
Sbjct  1    MRENFKNLGVVVVYYSLHDLHKQPINSFSLKTSNIIGFSIFICEHAQKEIMQKVASRHTD  60

Query  66   DSNKFNIKPKEKIDENVINALETSLKSKGVVSETLESIKEAKNNKEYENLSNRGFLRAKL  125
            +SNKFNIKPKEKIDENVINALETSLKSKGVVSETLESIKEAKNNKEYENLSNRGFLRAKL
Sbjct  61   NSNKFNIKPKEKIDENVINALETSLKSKGVVSETLESIKEAKNNKEYENLSNRGFLRAKL  120

Query  126  DQGVWINFQESLGYNLSTLQKKAISLLKISPNQILELVQKLYMKGHISYPTEYLFEETFK  185
            DQGV +NFQES+GYNLS+LQKKAISLLKISPNQILELVQKLYMKGHISYPTEYLFEETFK
Sbjct  121  DQGVGLNFQESIGYNLSALQKKAISLLKISPNQILELVQKLYMKGHISYPTEYLFEETFK  180

Query  186  KNLYKIYKDSENDCFNKNVADEEKVLLEFPSRKFTPNELFTAALLTLNAMEFCLYINSEK  245
            KNLYKIYKDSENDCFNKNVADEEKVLL FP+RKFTPNE+FTA+ LTLNAMEFCLYIN  K
Sbjct  181  KNLYKIYKDSENDCFNKNVADEEKVLLGFPNRKFTPNEFFTATSLTLNAMEFCLYINLKK  240

Query  246  KGN  248
            K  
Sbjct  241  KET  243

2) cag2 in NC_014256


> AY330640|2|G2|37811845|AAR03913.1|Helicobacter_pylori_Du52:2|+|562..1299|-|HP0521B|HP0521B 
protein
Length=245

 Score =  340 bits (1275),  Expect = 4e-95, Method: Compositional matrix adjust.
 Identities = 218/234 (94%), Positives = 224/234 (96%), Gaps = 0/234 (0%)

Query  1    MVYYSLHDPHKRPINSFSLKTSNIIGFSIFYLRTRTKKIIQKMASRHTDDSNKFNIKPKE  60
            +VYYSLHD HK+PINSFSLKTSNIIGFSIF      K I+QK+ASRHTD+SNKFNIKPKE
Sbjct  12   VVYYSLHDLHKQPINSFSLKTSNIIGFSIFICEHAQKEIMQKVASRHTDNSNKFNIKPKE  71

Query  61   KIDENVINALETSLKSKGVVSETLESIKEAKNNKEYENLSNRGFLRAKLDQGVGLNFQES  120
            KIDENVINALETSLKSKGVVSETLESIKEAKNNKEYENLSNRGFLRAKLDQGVGLNFQES
Sbjct  72   KIDENVINALETSLKSKGVVSETLESIKEAKNNKEYENLSNRGFLRAKLDQGVGLNFQES  131

Query  121  IGYNLSALQKKAISLLKISPNQILELVQKLYMKGRISYPTEYLFEETFKKNLYKIYKDSE  180
            IGYNLSALQKKAISLLKISPNQILELVQKLYMKG+ISYPTEYLFEETFKKNLYKIYKDSE
Sbjct  132  IGYNLSALQKKAISLLKISPNQILELVQKLYMKGHISYPTEYLFEETFKKNLYKIYKDSE  191

Query  181  NDCFNKNVDDEEKVLLGFPNRKFTPNEFFTATSLTLNAREFCLYINLKKKETNV  234
            NDCFNKNV DEEKVLLGFPNRKFTPNEFFTATSLTLNA EFCLYINLKKKETNV
Sbjct  192  NDCFNKNVADEEKVLLGFPNRKFTPNEFFTATSLTLNAMEFCLYINLKKKETNV  245

3) HPAG1_0496 in NC_008086


> AY330640|2|G2|37811845|AAR03913.1|Helicobacter_pylori_Du52:2|+|562..1299|-|HP0521B|HP0521B 
protein
Length=245

 Score =  329 bits (1236),  Expect = 5e-92, Method: Compositional matrix adjust.
 Identities = 209/222 (95%), Positives = 217/222 (98%), Gaps = 2/222 (0%)

Query  6    IRENLTNLGVLVVCYSLHDLHKQPINSFSLKTSNIIGFSIFICEHAQKKIMQKMASRHTD  65
            +REN+ NLGV+VV YSLHDLHKQPINSFSLKTSNIIGFSIFICEHAQK IMQK+ASRHTD
Sbjct  1    MRENFKNLGVVVVYYSLHDLHKQPINSFSLKTSNIIGFSIFICEHAQKEIMQKVASRHTD  60

Query  66   DSNKFNIKPKEKIDENVINALETSLKSKGVVSETLESIKEAKNNKEYENLSNRGFLRAKL  125
            +SNKFNIKPKEKIDENVINALETSLKSKGVVSETLESIKEAKNNKEYENLSNRGFLRAKL
Sbjct  61   NSNKFNIKPKEKIDENVINALETSLKSKGVVSETLESIKEAKNNKEYENLSNRGFLRAKL  120

Query  126  DQGVGINFQESLGYNLSALQKKAISLLKISPNQILELVQKLYMKGHRHISYPTEYLFEET  185
            DQGVG+NFQES+GYNLSALQKKAISLLKISPNQILELVQKLYMKG  HISYPTEYLFEET
Sbjct  121  DQGVGLNFQESIGYNLSALQKKAISLLKISPNQILELVQKLYMKG--HISYPTEYLFEET  178

Query  186  FKKNLYKIYKDSENDCFSKNVADEEKVLLGFPNRKFTPNEFF  227
            FKKNLYKIYKDSENDCF+KNVADEEKVLLGFPNRKFTPNEFF
Sbjct  179  FKKNLYKIYKDSENDCFNKNVADEEKVLLGFPNRKFTPNEFF  220