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PAthogenisity Island DataBase (PAI DB)

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Homologs of HP0521B gene of AY330638

protein-level

Hit (GenBank Accn)

Product

Source Genome

Eval.

Ident.(%)

1) HPAG1_0496
( YP_627237.1 )

HP0521B-like protein

NC_008086
(Helicobacter pylori HPAG1)

6e-99

2) HPB14_04040
( YP_006219523.1 )

HP0521B-like protein

NC_017733
(Helicobacter pylori HUP-B14)

3e-96

3) cag2
( YP_003728745.1 )

cag pathogenicity island protein epsilon

NC_014256
(Helicobacter pylori B8)

4e-82

• Sequence Alignments

1) HPAG1_0496 in NC_008086


> AY330638|2|G2|37811812|AAR03884.1|Helicobacter_pylori_Ca73|+|731..1447|-|HP0521B|HP0521B 
protein
Length=238

 Score =  353 bits (1324),  Expect = 6e-99, Method: Compositional matrix adjust.
 Identities = 226/239 (95%), Positives = 231/239 (97%), Gaps = 2/239 (0%)

Query  6    IRENLTNLGVLVVCYSLHDLHKQPINSFSLKTSNIIGFSIFICEHAQKKIMQKMASRHTD  65
            +REN+ NLGVLVV YSLHD HK+PINSFSLKTSNIIGFSIFICEHAQK IMQK+ASRHTD
Sbjct  1    MRENFKNLGVLVVYYSLHDPHKRPINSFSLKTSNIIGFSIFICEHAQKEIMQKVASRHTD  60

Query  66   DSNKFNIKPKEKIDENVINALETSLKSKGVVSETLESIKEAKNNKEYENLSNRGFLRAKL  125
            DSNKFNIKPKEKIDENVINALETSLKSKGVVSETLESIKEAKNNKEYENLSNRGFLRAKL
Sbjct  61   DSNKFNIKPKEKIDENVINALETSLKSKGVVSETLESIKEAKNNKEYENLSNRGFLRAKL  120

Query  126  DQGVGINFQESLGYNLSALQKKAISLLKISPNQILELVQKLYMKGHRHISYPTEYLFEET  185
            DQGV INFQESLGYNLSALQKKAISLLKI+PNQILELVQKLYMKG  HISYPTEYLFEET
Sbjct  121  DQGVWINFQESLGYNLSALQKKAISLLKITPNQILELVQKLYMKG--HISYPTEYLFEET  178

Query  186  FKKNLYKIYKDSENDCFSKNVADEEKVLLGFPNRKFTPNEFFYSCITYLKCKGILSLYQ  244
            FKKNLYKIYKDSENDCFSKNVADEEKVLLGFPNRKFTPNE FYSCITYLKCKGILSLYQ
Sbjct  179  FKKNLYKIYKDSENDCFSKNVADEEKVLLGFPNRKFTPNESFYSCITYLKCKGILSLYQ  237

2) HPB14_04040 in NC_017733


> AY330638|2|G2|37811812|AAR03884.1|Helicobacter_pylori_Ca73|+|731..1447|-|HP0521B|HP0521B 
protein
Length=238

 Score =  344 bits (1290),  Expect = 3e-96, Method: Compositional matrix adjust.
 Identities = 214/220 (98%), Positives = 218/220 (99%), Gaps = 0/220 (0%)

Query  6    MRENFKNLGVLVVYYSLHDPHKRPINSFSLKTSNIIGFSIFICEHAQKEIMQKVASRHTD  65
            MRENFKNLGVLVVYYSLHDPHKRPINSFSLKTSNIIGFSIFICEHAQKEIMQKVASRHTD
Sbjct  1    MRENFKNLGVLVVYYSLHDPHKRPINSFSLKTSNIIGFSIFICEHAQKEIMQKVASRHTD  60

Query  66   DSNKFNIKPKEKIDENVINALETSLKSKGVVSETLESIKEAKNNKEYENLSNRGFLRAKL  125
            DSNKFNIKPKEKIDENVINALETSLKSKGVVSETLESIKEAKNNKEYENLSNRGFLRAKL
Sbjct  61   DSNKFNIKPKEKIDENVINALETSLKSKGVVSETLESIKEAKNNKEYENLSNRGFLRAKL  120

Query  126  DQGVWINFQESLGYNLSTLQKKAISLLKISPNQILELVQKLYMKGHISYPTEYLFEETFK  185
            DQGVWINFQESLGYNLS+LQKKAISLLKI+PNQILELVQKLYMKGHISYPTEYLFEETFK
Sbjct  121  DQGVWINFQESLGYNLSALQKKAISLLKITPNQILELVQKLYMKGHISYPTEYLFEETFK  180

Query  186  KNLYKIYKDSENDCFNKNVADEEKVLLEFPSRKFTPNELF  225
            KNLYKIYKDSENDCF+KNVADEEKVLL FP+RKFTPNE F
Sbjct  181  KNLYKIYKDSENDCFSKNVADEEKVLLGFPNRKFTPNESF  220

3) cag2 in NC_014256


> AY330638|2|G2|37811812|AAR03884.1|Helicobacter_pylori_Ca73|+|731..1447|-|HP0521B|HP0521B 
protein
Length=238

 Score =  296 bits (1110),  Expect = 4e-82, Method: Compositional matrix adjust.
 Identities = 191/214 (90%), Positives = 202/214 (95%), Gaps = 1/214 (0%)

Query  1    MVYYSLHDPHKRPINSFSLKTSNIIGFSIFYLRTRTKKIIQKMASRHTDDSNKFNIKPKE  60
            +VYYSLHDPHKRPINSFSLKTSNIIGFSIF      K I+QK+ASRHTDDSNKFNIKPKE
Sbjct  12   VVYYSLHDPHKRPINSFSLKTSNIIGFSIFICEHAQKEIMQKVASRHTDDSNKFNIKPKE  71

Query  61   KIDENVINALETSLKSKGVVSETLESIKEAKNNKEYENLSNRGFLRAKLDQGVGLNFQES  120
            KIDENVINALETSLKSKGVVSETLESIKEAKNNKEYENLSNRGFLRAKLDQGV +NFQES
Sbjct  72   KIDENVINALETSLKSKGVVSETLESIKEAKNNKEYENLSNRGFLRAKLDQGVWINFQES  131

Query  121  IGYNLSALQKKAISLLKISPNQILELVQKLYMKGRISYPTEYLFEETFKKNLYKIYKDSE  180
            +GYNLSALQKKAISLLKI+PNQILELVQKLYMKG+ISYPTEYLFEETFKKNLYKIYKDSE
Sbjct  132  LGYNLSALQKKAISLLKITPNQILELVQKLYMKGHISYPTEYLFEETFKKNLYKIYKDSE  191

Query  181  NDCFNKNVDDEEKVLLGFPNRKFTPNE-FFTATS  213
            NDCF+KNV DEEKVLLGFPNRKFTPNE F++  +
Sbjct  192  NDCFSKNVADEEKVLLGFPNRKFTPNESFYSCIT  225