Homologs of copR gene of AF060858

Hit (GenBank Accn)	Product	Source Genome	Eval.	Ident.(%)
1) copR   ( YP_002243090.1 )	transcriptional regulatory protein YedW	NC_011294 (Salmonella enterica P125109)	5e-113	99
2) copR   ( YP_002638196.1 )	transcriptional regulator YedW	NC_012125 (Salmonella enterica RKS4594)	5e-113	99
3) STMMW_11061   ( YP_005232162.1 )	response regulator	NC_016854 (Salmonella enterica D23580)	1e-112	98
4) copR   ( YP_005180948.1 )	response regulator	NC_016810 (Salmonella enterica SL1344)	1e-112	98
5) copR   ( YP_005251606.1 )	transcriptional regulatory protein YedW	NC_016863 (Salmonella enterica UK-1)	1e-112	98
6) copR   ( YP_002226050.1 )	transcriptional regulator YedW	NC_011274 (Salmonella enterica 287/91)	2e-112	98
7) copR   ( NP_455593.3 )	response regulator	NC_003198 (Salmonella enterica CT18)	1e-110	97
8) SEEB0189_14090   ( YP_008309130.1 )	transcriptional regulator	NC_021844 (Salmonella enterica CFSAN000189)	3e-102	99
9) SeD_A1171   ( YP_002215027.1 )	transcriptional regulatory protein YedW	NC_011205 (Salmonella enterica CT_02021853)	3e-102	99
10) SeSA_A1160   ( YP_002114094.1 )	transcriptional regulatory protein YedW	NC_011094 (Salmonella enterica CVM19633)	3e-102	99
11) SPAB_02459   ( YP_001588673.1 )	transcriptional regulatory protein YedW	NC_010102 (Salmonella enterica SGSC4150; SPB7)	3e-102	99
12) SeAg_B1055   ( YP_002145965.1 )	transcriptional regulatory protein YedW	NC_011149 (Salmonella enterica SL483)	3e-102	99
13) copR   ( YP_216033.2 )	transcriptional regulatory protein YedW	NC_006905 (Salmonella enterica SC-B67)	4e-102	99
14) SSPA1630   ( YP_002142470.1 )	transcriptional regulatory protein YedW	NC_011147 (Salmonella enterica AKU12601)	5e-102	98
15) copR   ( YP_150985.1 )	response regulator	NC_006511 (Salmonella enterica ATCC 9150)	5e-102	98
16) SE451236_11330   ( YP_008265295.1 )	transcriptional regulator	NC_021820 (Salmonella enterica 08-1736)	6e-102	98
17) copR   ( YP_005236830.1 )	transcriptional regulatory protein YedW	NC_016856 (Salmonella enterica 14028S)	6e-102	98
18) copR   ( YP_005396511.1 )	response regulator	NC_017046 (Salmonella enterica 798)	6e-102	98
19) CFSAN001921_11695   ( YP_008255709.1 )	transcriptional regulator	NC_021814 (Salmonella enterica CFSAN001921)	6e-102	98
20) copR   ( NP_460069.2 )	transcriptional regulatory protein YedW	NC_003197 (Salmonella enterica LT2)	6e-102	98
21) copR   ( YP_005241992.1 )	transcriptional regulatory protein YedW	NC_016857 (Salmonella enterica ST4/74)	6e-102	98
22) STMDT12_C11150   ( YP_005246811.1 )	transcriptional regulator YedW	NC_016860 (Salmonella enterica T000240)	6e-102	98
23) STU288_01810   ( YP_007901467.1 )	transcriptional regulatory protein YedW	NC_021151 (Salmonella enterica U288)	6e-102	98
24) copR   ( YP_008481576.1 )	response regulator	NC_022221 (Salmonella enterica CDC1983-67)	7e-102	98
25) copR   ( YP_005213119.1 )	response regulator	NC_016831 (Salmonella enterica RKS5078)	7e-102	98
26) I137_08915   ( YP_008381252.1 )	transcriptional regulator	NC_021984 (Salmonella enterica S06004)	7e-102	98
27) SBOV10091   ( YP_008504882.1 )	transcriptional activator protein IrlR	NC_022241 (Salmonella enterica 3114)	8e-102	98
28) SNSL254_A1191   ( YP_002040351.1 )	transcriptional regulatory protein YedW	NC_011080 (Salmonella enterica SL254)	8e-102	98
29) SN31241_21630   ( YP_008360080.1 )	transcriptional regulatory protein YedW	NC_021902 (Salmonella enterica USMARC-S3124.1)	8e-102	98
30) CFSAN002050_11875   ( YP_008260290.1 )	transcriptional regulator	NC_021818 (Salmonella enterica CFSAN002050)	4e-101	98
31) copR   ( YP_004729825.1 )	response regulator	NC_015761 (Salmonella bongori NCTC 12419)	1e-100	92
32) STBHUCCB_19400   ( YP_005217480.1 )	transcriptional regulatory protein yedW	NC_016832 (Salmonella enterica P-stx-12)	5e-100	97
33) copR   ( NP_805595.2 )	transcriptional regulator YedW	NC_004631 (Salmonella enterica Ty2)	5e-100	97
34) TY21A_09280   ( YP_007926142.1 )	transcriptional regulatory protein YedW	NC_021176 (Salmonella enterica Ty21a)	5e-100	97
35) SARI_01907   ( YP_001570932.1 )	transcriptional regulatory protein YedW	NC_010067 (Salmonella enterica RSK2980)	1e-98	95
36) A464_1035   ( YP_008321631.1 )	Putative two-component system response regulator YedW	NC_021870 (Salmonella bongori N268-08)	3e-96	92
37) SU5_01727   ( YP_006087363.1 )	Putative two-component system response regulatorYedW	NC_017623 (Salmonella enterica B182)	2e-88	98
38) ROD_50441   ( YP_003368401.1 )	two-component response regulator	NC_013716 (Citrobacter rodentium ICC168)	6e-85	78
39) ECP_1902   ( YP_669804.1 )	transcriptional regulatory protein YedW	NC_008253 (Escherichia coli 536)	2e-82	74
40) yedW   ( YP_006106285.1 )	heavy metal response regulator	NC_017631 (Escherichia coli ABU 83972)	2e-82	74
41) yedW   ( YP_006154309.1 )	transcriptional regulatory protein YedW	NC_017652 (Escherichia coli clone D i14)	2e-82	74
42) yedW   ( YP_006149390.1 )	transcriptional regulatory protein YedW	NC_017651 (Escherichia coli clone D i2)	2e-82	74
43) yedW   ( YP_006139017.1 )	Putative transcriotional regulator	NC_017644 (Escherichia coli NA114)	2e-82	74
44) NRG857_09830   ( YP_006120321.1 )	transcriptional regulatory protein YedW	NC_017634 (Escherichia coli NRG 857C)	2e-82	74
45) yedW   ( YP_005727688.1 )	Two component heavy metal response transcriptional regulator, winged helix family precursor	NC_017328 (Shigella flexneri 2002017)	2e-82	74
46) yedW   ( YP_689459.1 )	transcriptional regulatory protein YedW	NC_008258 (Shigella flexneri 8401)	2e-82	74
47) yedW   ( YP_853018.1 )	transcriptional regulatory protein YedW	NC_008563 (Escherichia coli APEC O1)	2e-82	74
48) yedW   ( YP_003499962.1 )	Heavy metal response regulator	NC_013941 (Escherichia coli CB9615)	2e-82	74
49) ECOK1_2082   ( YP_006101262.1 )	heavy metal response regulator	NC_017628 (Escherichia coli IHE3034)	2e-82	74
50) yedW   ( YP_008571897.1 )	putative transcriptional regulatory protein YedW	NC_022370 (Escherichia coli PMV-1)	2e-82	74
51) UM146_07355   ( YP_006110374.1 )	transcriptional regulatory protein YedW	NC_017632 (Escherichia coli UM146)	2e-82	74
52) EcolC_1676   ( YP_001724655.1 )	transcriptional regulatory protein YedW	NC_010468 (Escherichia coli ATCC 8739)	3e-82	74
53) yedW   ( YP_006144313.1 )	putative DNA-binding response regulator in two-component system with YedV	NC_017646 (Escherichia coli CE10)	3e-82	74
54) EcE24377A_2200   ( YP_001463269.1 )	transcriptional regulatory protein YedW	NC_009801 (Escherichia coli E24377A)	3e-82	74
55) EcHS_A2070   ( YP_001458755.1 )	transcriptional regulatory protein YedW	NC_009800 (Escherichia coli HS)	3e-82	74
56) EKO11_1807   ( YP_005277489.1 )	two component heavy metal response transcriptional regulator, winged helix family	NC_016902 (Escherichia coli KO11FL)	3e-82	74
57) yedW   ( YP_006164901.1 )	transcriptional regulatory protein YedW	NC_017660 (Escherichia coli KO11FL)	3e-82	74
58) P12B_c1054   ( YP_006168092.1 )	Heavy metal response regulator	NC_017663 (Escherichia coli P12b)	3e-82	74
59) EcSMS35_1216   ( YP_001743277.1 )	transcriptional regulatory protein YedW	NC_010498 (Escherichia coli SMS-3-5)	3e-82	74
60) yedW   ( YP_006124833.1 )	DNA-binding response regulator in two-component system with YedV	NC_017635 (Escherichia coli W)	3e-82	74
61) yedW   ( YP_006173546.1 )	transcriptional regulatory protein YedW	NC_017664 (Escherichia coli W)	3e-82	74
62) SbBS512_E0914   ( YP_001879602.1 )	transcriptional regulator YedW	NC_010658 (Shigella boydii CDC 3083-94)	3e-82	74
63) EcDH1_1682   ( YP_006091633.1 )	two component heavy metal response transcriptional regulator, winged helix family	NC_017625 (Escherichia coli DH1)	4e-82	74
64) yedW   ( YP_006129310.1 )	transcriptional regulatory protein YedW	NC_017638 (Escherichia coli DH1)	4e-82	74
65) ECBD_1678   ( YP_003035916.1 )	transcriptional regulatory protein YedW	NC_012947 (Escherichia coli Escherichia coli BL21-Gold(DE3)pLysS AG)	4e-82	74
66) EC042_2125   ( YP_006096431.1 )	two-component response regulator	NC_017626 (Escherichia coli 042)	4e-82	74
67) LY180_10195   ( YP_008565138.1 )	transcriptional regulator	NC_022364 (Escherichia coli LY180)	4e-82	74
68) ECH74115_2748   ( YP_002271082.1 )	transcriptional regulatory protein YedW	NC_011353 (Escherichia coli EC4115)	7e-82	74
69) ECSF_1818   ( YP_003349808.1 )	two-component response regulator	NC_013654 (Escherichia coli SE15)	7e-82	74
70) yedW   ( NP_754279.2 )	transcriptional regulatory protein YedW	NC_004431 (Escherichia coli CFT073)	3e-80	76
71) yedW   ( YP_002556839.1 )	transcriptional regulatory protein yedW	NC_011993 (Escherichia coli LF82)	3e-80	76
72) yedW   ( NP_837578.1 )	transcriptional regulatory protein YedW	NC_004741 (Shigella flexneri 2457T)	3e-80	76
73) yedW   ( NP_707854.2 )	transcriptional regulatory protein YedW	NC_004337 (Shigella flexneri 301)	3e-80	76
74) yedW   ( YP_002387460.1 )	transcriptional regulatory protein YedW	NC_011741 (Escherichia coli IAI1)	4e-80	76
75) SSON53_11995   ( YP_005456933.1 )	transcriptional regulatory protein YedW	NC_016822 (Shigella sonnei 53G)	4e-80	76
76) yedW   ( YP_310926.2 )	transcriptional regulatory protein YedW	NC_007384 (Shigella sonnei Ss046)	4e-80	76
77) yedW   ( YP_003234961.1 )	putative DNA-binding response regulator in two-component system with YedV	NC_013364 (Escherichia coli 11128)	5e-80	76
78) yedW   ( YP_003229829.1 )	transcriptional regulatory protein YedW	NC_013361 (Escherichia coli 11368)	5e-80	76
79) yedW   ( YP_003222143.1 )	DNA-binding response regulator in two-component system with YedV	NC_013353 (Escherichia coli 12009)	5e-80	76
80) APECO78_13625   ( YP_007381898.1 )	transcriptional regulatory protein YedW	NC_020163 (Escherichia coli APEC O78)	5e-80	76
81) yedW   ( YP_002999664.1 )	DNA-binding response regulator in two-component system with YedV	NC_012892 (Escherichia coli BL21(DE3))	5e-80	76
82) yedW   ( YP_003054509.1 )	DNA-binding response regulator in two-component system with YedV	NC_012971 (Escherichia coli BL21(DE3))	5e-80	76
83) yedW   ( YP_002398174.1 )	transcriptional regulatory protein YedW	NC_011745 (Escherichia coli ED1a)	5e-80	76
84) yedW   ( NP_288428.2 )	transcriptional regulatory protein YedW	NC_002655 (Escherichia coli EDL933)	5e-80	76
85) ETEC_2069   ( YP_006115635.1 )	two-component response regulator	NC_017633 (Escherichia coli ETEC H10407)	5e-80	76
86) yedW   ( YP_003045081.1 )	transcriptional regulatory protein YedW	NC_012967 (Escherichia coli REL606)	5e-80	76
87) ECO55CA74_11635   ( YP_006159464.1 )	transcriptional regulatory protein YedW	NC_017656 (Escherichia coli RM12579)	5e-80	76
88) yedW   ( YP_002391736.1 )	transcriptional regulatory protein YedW	NC_011742 (Escherichia coli S88)	5e-80	76
89) ECs2707   ( NP_310734.2 )	transcriptional regulatory protein YedW	NC_002695 (Escherichia coli Sakai)	5e-80	76
90) ECSE_2198   ( YP_002293473.1 )	transcriptional regulatory protein YedW	NC_011415 (Escherichia coli SE11)	5e-80	76
91) yedW   ( YP_003078458.1 )	transcriptional regulatory protein YedW	NC_013008 (Escherichia coli TW14359)	5e-80	76
92) yedW   ( YP_002412979.1 )	transcriptional regulatory protein YedW	NC_011751 (Escherichia coli UMN026)	5e-80	76
93) irlR   ( YP_006134190.1 )	transcriptional activator protein IrlR	NC_017641 (Escherichia coli UMNK88)	5e-80	76
94) yedW   ( YP_541172.2 )	transcriptional regulatory protein YedW	NC_007946 (Escherichia coli UTI89)	5e-80	76
95) CDCO157_2501   ( YP_006313371.1 )	transcriptional regulatory protein YedW	NC_017906 (Escherichia coli Xuzhou21)	5e-80	76
96) yedW   ( YP_407518.2 )	transcriptional regulatory protein YedW	NC_007613 (Shigella boydii Sb227)	5e-80	76
97) O3M_09730   ( YP_006769597.1 )	transcriptional regulatory protein YedW	NC_018650 (Escherichia coli 2009EL-2050)	6e-80	76
98) O3O_15860   ( YP_006783722.1 )	transcriptional regulatory protein YedW	NC_018661 (Escherichia coli 2009EL-2071)	6e-80	76
99) O3K_09765   ( YP_006778650.1 )	transcriptional regulatory protein YedW	NC_018658 (Escherichia coli 2011C-3493)	6e-80	76
100) yedW   ( YP_002403241.1 )	transcriptional regulatory protein YedW	NC_011748 (Escherichia coli 55989)	6e-80	76
101) yedW   ( YP_002407100.1 )	transcriptional regulatory protein YedW	NC_011750 (Escherichia coli IAI39)	6e-80	76
102) yedW   ( YP_002329596.1 )	transcriptional regulatory protein YedW	NC_011601 (Escherichia coli E2348/69)	7e-80	76
103) yedW   ( YP_001730929.1 )	transcriptional regulatory protein YedW	NC_010473 (Escherichia coli K-12)	7e-80	75
104) yedW   ( YP_002926966.1 )	transcriptional regulatory protein YedW	NC_012759 (Escherichia coli K-12)	7e-80	75
105) yedW   ( YP_007557228.1 )	predicted DNA-binding response regulator in two-component system withYedV	NC_020518 (Escherichia coli K-12)	7e-80	75
106) yedW   ( YP_490219.1 )	DNA-binding response regulator in two-component system withYedV	NC_007779 (Escherichia coli K-12)	7e-80	75
107) yedW   ( NP_416478.2 )	predicted DNA-binding response regulator in two-component system with YedV	NC_000913 (Escherichia coli K12)	7e-80	75
108) SEEH1578_14705   ( YP_008247000.1 )	transcriptional regulatory protein YedW	NC_021810 (Salmonella enterica 41578)	2e-78	99
109) yedW   ( YP_006341190.1 )	transcriptional regulatory protein YedW	NC_017933 (Cronobacter sakazakii ES15)	3e-78	67
110) ESA_04133   ( YP_001440151.1 )	transcriptional regulatory protein YedW	NC_009778 (Cronobacter sakazakii ATCC BAA-894)	3e-76	70
111) yedW   ( YP_003212466.1 )	transcriptional regulatory protein YedW	NC_013282 (Cronobacter turicensis z3032)	6e-76	70
112) CSSP291_19155   ( YP_007442683.1 )	transcriptional regulatory protein YedW	NC_020260 (Cronobacter sakazakii Sp291)	9e-76	70
113) yedW   ( YP_402695.2 )	transcriptional regulatory protein YedW	NC_007606 (Shigella dysenteriae Sd197)	1e-74	74
114) yedW   ( YP_006318929.1 )	heavy metal response regulator YedW	NC_017910 (Escherichia blattae DSM 4481)	2e-73	70
115) MU9_2070   ( YP_007505489.1 )	Putative two-component system response regulator YedW	NC_020418 (Morganella morganii KT)	7e-68	64
116) DSC_03840   ( YP_004929462.1 )	two component heavy metal response transcriptional regulator	NC_016147 (Pseudoxanthomonas spadix BD-a59)	7e-62	60
117) CtCNB1_2500   ( YP_003278542.1 )	two component heavy metal response transcriptional regulator	NC_013446 (Comamonas testosteroni CNB-1)	8e-62	61
118) ambt_07195   ( YP_004466774.1 )	putative two component response regulator transcription regulator protein	NC_015554 (Alteromonas sp. SN2)	2e-61	55
119) cusR   ( YP_006185079.1 )	Copper-sensing two-component system response regulator CusR	NC_017671 (Stenotrophomonas maltophilia D457)	4e-61	60
120) czcR   ( YP_003776448.1 )	cobalt/zinc/cadmium resistance two component response regulator protein	NC_014323 (Herbaspirillum seropedicae SmR1)	6e-61	55
121) Smlt2693   ( YP_001972461.1 )	two-component response regulator transcriptional regulator	NC_010943 (Stenotrophomonas maltophilia K279a)	1e-60	60
122) TOL_0557   ( YP_007681235.1 )	heavy metal response regulator	NC_020888 (Thalassolituus oleivorans MIL-1)	1e-60	55
123) Rpic12D_5099   ( YP_002973577.1 )	two component heavy metal response transcriptional regulator, winged helix family	NC_012849 (Ralstonia pickettii 12D)	2e-60	60
124) BurJV3_2210   ( YP_004792759.1 )	two component heavy metal response winged helix family transcriptional regulator	NC_015947 (Stenotrophomonas maltophilia JV3)	2e-60	58
125) Q7A_1812   ( YP_006296275.1 )	heavy metal response regulator	NC_017857 (Methylophaga sp. JAM1)	2e-60	56
126) copR2   ( YP_001353412.1 )	response regulator of copper sensing system	NC_009659 (Janthinobacterium sp. Marseille)	2e-60	55
127) Smal_2165   ( YP_002028552.1 )	two component heavy metal response transcriptional regulator, winged helix family	NC_011071 (Stenotrophomonas maltophilia R551-3)	4e-60	58
128) Kkor_1292   ( YP_003146476.1 )	two component heavy metal response transcriptional regulator, winged helix family	NC_013166 (Kangiella koreensis DSM 16069)	5e-60	58
129) Tmz1t_3985   ( YP_002890945.1 )	winged helix family two component heavy metal response transcriptional regulator	NC_011662 (Thauera sp. MZ1T)	7e-60	60
130) czcR2   ( YP_001354044.1 )	heavy metal response regulator	NC_009659 (Janthinobacterium sp. Marseille)	1e-59	61
131) czcR   ( YP_006891859.1 )	winged-helix heavy metal transcriptional response regulator	NC_017454 (Geobacter sulfurreducens KN400)	1e-59	58
132) czcR   ( NP_953988.1 )	winged-helix heavy metal transcriptional response regulator	NC_002939 (Geobacter sulfurreducens PCA)	1e-59	58
133) PT7_1815   ( YP_004416979.1 )	two component heavy metal response transcriptional regulator, winged helix family protein	NC_015458 (Pusillimonas sp. T7-7)	7e-60	59
134) copR   ( YP_001099843.1 )	response regulator in two-component regulatory system with CusS, regulation of copper resistance	NC_009138 (Herminiimonas arsenicoxydans )	7e-60	55
135) Tmz1t_4055   ( YP_002891010.1 )	winged helix family two component heavy metal response transcriptional regulator	NC_011662 (Thauera sp. MZ1T)	9e-60	59
136) Neut_0018   ( YP_746275.1 )	two component heavy metal response transcriptional regulator, winged helix family protein	NC_008344 (Nitrosomonas eutropha C91)	2e-59	58
137) Pnap_4558   ( YP_973572.1 )	two component heavy metal response transcriptional regulator	NC_008758 (Polaromonas naphthalenivorans CJ2)	4e-59	56
138) czcR   ( YP_003749414.1 )	response regulator in two-component regulatory system, regulation of heavy metal resistance operon czcCBA	NC_014310 (Ralstonia solanacearum PSI07)	1e-58	55
139) CFU_2527   ( YP_004753177.1 )	putative response regulator for cobalt zinc cadmium resistance transcription regulator protein	NC_015856 (Collimonas fungivorans Ter331)	6e-59	57
140) czcR   ( YP_006031504.1 )	response regulator protein for cobalt zinc cadmium resistance	NC_017575 (Ralstonia solanacearum Po82)	6e-59	56
141) TOL_1710   ( YP_007682373.1 )	heavy metal response regulator	NC_020888 (Thalassolituus oleivorans MIL-1)	8e-59	54
142) PT7_1097   ( YP_004416261.1 )	two component heavy metal response transcriptional regulator, winged helix family protein	NC_015458 (Pusillimonas sp. T7-7)	9e-59	58
143) Gura_1986   ( YP_001230749.1 )	two component heavy metal response transcriptional regulator	NC_009483 (Geobacter uraniireducens Rf4)	1e-58	56
144) C380_05635   ( YP_006853480.1 )	two component heavy metal response transcriptional regulator	NC_018708 (Acidovorax sp. KKS102)	2e-58	57
145) C380_06140   ( YP_006853577.1 )	two component heavy metal response transcriptional regulator	NC_018708 (Acidovorax sp. KKS102)	2e-58	57
146) Glaag_4527   ( YP_004436705.1 )	two component heavy metal response transcriptional regulator, winged helix family	NC_015498 (Glaciecola sp. 4H-3-7+YE-5)	2e-58	55
147) F504_3876   ( YP_008237607.1 )	DNA-binding heavy metal response regulator	NC_021745 (Ralstonia solanacearum FQY_4)	2e-58	55
148) czcR   ( NP_522050.1 )	response regulator for cobalt zinc cadmium resistance transcription regulator protein	NC_003296 (Ralstonia solanacearum GMI1000)	2e-58	55
149) PST_3390   ( YP_001173860.1 )	transcriptional activator CopR	NC_009434 (Pseudomonas stutzeri A1501)	3e-58	57
150) Geob_3169   ( YP_002538613.1 )	two component heavy metal response transcriptional regulator, winged helix family	NC_011979 (Geobacter daltonii FRC-32)	4e-58	56
151) Pmen_1174   ( YP_001186671.1 )	two component heavy metal response transcriptional regulator	NC_009439 (Pseudomonas mendocina ymp)	5e-58	55
152) amad1_01395   ( YP_006975164.1 )	two component response regulator transcriptional regulator	NC_019393 (Alteromonas macleodii AltDE1)	5e-58	53
153) AMBLS11_01205   ( YP_006823290.1 )	two component response regulator transcriptional regulator	NC_018692 (Alteromonas macleodii Black Sea 11)	5e-58	53
154) MADE_1001535   ( YP_004425454.1 )	XRE family transcriptional regulator	NC_011138 (Alteromonas macleodii Deep ecotype)	5e-58	53
155) I607_01380   ( YP_008170346.1 )	two component response regulator transcriptional regulator	NC_021710 (Alteromonas macleodii Ionian Sea U4)	5e-58	53
156) I876_01635   ( YP_008194755.1 )	two component response regulator transcriptional regulator	NC_021717 (Alteromonas macleodii Ionian Sea U7)	5e-58	53
157) I634_01595   ( YP_008174471.1 )	two component response regulator transcriptional regulator	NC_021712 (Alteromonas macleodii Ionian Sea U8)	5e-58	53
158) I636_01365   ( YP_008182271.1 )	two component response regulator transcriptional regulator	NC_021714 (Alteromonas macleodii Ionian Sea UM4b)	5e-58	53
159) I635_01395   ( YP_008178226.1 )	two component response regulator transcriptional regulator	NC_021713 (Alteromonas macleodii Ionian Sea UM7)	5e-58	53
160) cusR   ( YP_003625482.1 )	Transcriptional regulatory protein cusR	NC_014145 (Thiomonas sp. 3As)	6e-58	53
161) Daro_2259   ( YP_285466.1 )	two component heavy metal response transcriptional regulator	NC_007298 (Dechloromonas aromatica RCB)	1e-57	60
162) A458_05115   ( YP_006456694.1 )	two-component response regulator	NC_018028 (Pseudomonas stutzeri CCUG 29243)	1e-57	56
163) irlR5   ( YP_003981756.1 )	transcriptional activator protein IrlR 5	NC_014640 (Achromobacter xylosoxidans A8)	1e-57	55
164) irlR   ( YP_005939886.1 )	two-component response regulator	NC_017532 (Pseudomonas stutzeri DSM 4166)	1e-57	55
165) Tint_1277   ( YP_003642995.1 )	winged helix family two component transcriptional regulator	NC_014153 (Thiomonas intermedia K12)	1e-57	54
166) czcR   ( YP_003624112.1 )	Transcriptional activator protein czcR	NC_014145 (Thiomonas sp. 3As)	1e-57	54
167) Pput_0017   ( YP_001265378.1 )	two component heavy metal response transcriptional regulator	NC_009512 (Pseudomonas putida F1)	2e-57	56
168) PputGB1_0019   ( YP_001666271.1 )	two component heavy metal response transcriptional regulator	NC_010322 (Pseudomonas putida GB-1)	2e-57	56
169) B479_00330   ( YP_007226927.1 )	two component heavy metal response transcriptional regulator	NC_019905 (Pseudomonas putida PC9)	2e-57	56
170) PputW619_0017   ( YP_001746892.1 )	two component heavy metal response transcriptional regulator	NC_010501 (Pseudomonas putida W619)	2e-57	56
171) CAP2UW1_0147   ( YP_003165436.1 )	winged helix family two component heavy metal response transcriptional regulator	NC_013194 (Candidatus Accumulibacter phosphatis UW-1)	8e-58	58
172) Pfl01_3624   ( YP_349353.1 )	two component heavy metal response transcriptional regulator	NC_007492 (Pseudomonas fluorescens Pf0-1)	9e-58	53
173) copR   ( YP_004714874.1 )	transcriptional activator CopR	NC_015740 (Pseudomonas stutzeri ATCC 17588)	2e-57	57
174) Dtpsy_2215   ( YP_002553654.1 )	winged helix family two component heavy metal response transcriptional regulator	NC_011992 (Acidovorax ebreus TPSY)	2e-57	55
175) Alide2_3404   ( YP_004389251.1 )	two component heavy metal response transcriptional regulator	NC_015422 (Alicycliphilus denitrificans K601)	2e-57	55
176) PSJM300_10730   ( YP_006524568.1 )	transcriptional activator CopR	NC_018177 (Pseudomonas stutzeri DSM 10701)	3e-57	57
177) Sde_1948   ( YP_527420.1 )	Heavy metal response regulator	NC_007912 (Saccharophagus degradans 2-40)	3e-57	55
178) Tmz1t_2101   ( YP_002355738.1 )	winged helix family two component heavy metal response transcriptional regulator	NC_011662 (Thauera sp. MZ1T)	3e-57	55
179) Tmz1t_2388   ( YP_002364216.1 )	heavy metal response regulator	NC_011667 (Thauera sp. MZ1T)	3e-57	55
180) copR   ( YP_006323096.1 )	DNA-binding copper response regulator	NC_017911 (Pseudomonas fluorescens A506)	4e-57	57
181) CAP2UW1_4708   ( YP_003165280.1 )	hypothetical protein	NC_013193 (Candidatus Accumulibacter phosphatis UW-1)	5e-57	58
182) Pfl01_3855   ( YP_349583.1 )	two component heavy metal response transcriptional regulator	NC_007492 (Pseudomonas fluorescens Pf0-1)	6e-57	55
183) Bmul_6173   ( YP_001573626.1 )	two component heavy metal response transcriptional regulator	NC_010070 (Burkholderia multivorans ATCC 17616)	6e-57	54
184) CKO_02615   ( YP_001454160.1 )	DNA-binding transcriptional activator CusR	NC_009792 (Citrobacter koseri ATCC BAA-895)	6e-57	53
185) Entcl_2025   ( YP_003941564.1 )	two component heavy metal response transcriptional regulator, winged helix family	NC_014618 (Enterobacter cloacae SCF1)	6e-57	53
186) Daro_2474   ( YP_285679.1 )	heavy metal response regulator	NC_007298 (Dechloromonas aromatica RCB)	1e-56	58
187) Psyr_1497   ( YP_234585.1 )	heavy metal response regulator	NC_007005 (Pseudomonas syringae B728a)	1e-56	57
188) cusR   ( YP_001942028.1 )	two-component system copper resistance phosphate regulon response regulator	NC_010802 (Burkholderia multivorans ATCC 17616)	1e-56	55
189) DelCs14_5429   ( YP_004490754.1 )	two component heavy metal response transcriptional regulator, winged helix family	NC_015563 (Delftia sp. Cs1-4)	1e-56	54
190) Tgr7_1208   ( YP_002513281.1 )	two component heavy metal response transcriptional regulator, winged helix family	NC_011901 (Thioalkalivibrio sulfidophilus HL-EbGR7)	7e-57	59
191) CtCNB1_4385   ( YP_003280427.1 )	two component heavy metal response	NC_013446 (Comamonas testosteroni CNB-1)	7e-57	56
192) irlR   ( YP_004715526.1 )	DNA-binding heavy metal response regulator	NC_015740 (Pseudomonas stutzeri ATCC 17588)	7e-57	55
193) Pat9b_5763   ( YP_004118475.1 )	two component transcriptional regulator, winged helix family	NC_014838 (Pantoea sp. At-9b)	7e-57	51
194) Psest_1185   ( YP_007239379.1 )	two component heavy metal response transcriptional regulator, winged helix family	NC_019936 (Pseudomonas stutzeri RCH2)	8e-57	56
195) copR   ( NP_747484.1 )	two component heavy metal response transcriptional regulator	NC_002947 (Pseudomonas putida KT2440)	1e-56	54
196) PSF113_4774   ( YP_005210158.1 )	DNA-binding heavy metal response regulator	NC_016830 (Pseudomonas fluorescens F113)	2e-56	55
197) AB57_0661   ( YP_002318064.1 )	transcriptional activator protein CusR	NC_011586 (Acinetobacter baumannii AB0057)	2e-56	54
198) copR   ( YP_001714983.1 )	transcriptional activator protein	NC_010410 (Acinetobacter baumannii AYE)	2e-56	54
199) H681_17275   ( YP_007658863.1 )	putative two-component response regulator	NC_020829 (Pseudomonas denitrificans ATCC 13867)	2e-56	53
200) EbC_09000   ( YP_003740289.1 )	two component heavy metal response transcriptional regulator	NC_014306 (Erwinia billingiae Eb661)	3e-56	57
201) Rahaq2_1442   ( YP_005199461.1 )	heavy metal response regulator	NC_016818 (Rahnella aquatilis CIP 78.65)	3e-56	56
202) PSEBR_a4612   ( YP_004356032.1 )	two-component response regulator	NC_015379 (Pseudomonas brassicacearum NFM421)	3e-56	55
203) czcR1   ( YP_007997507.1 )	transcriptional activator protein CzcR	NC_021237 (Pseudomonas fluorescens CHA0)	3e-56	55
204) PFL_0200   ( YP_257346.1 )	DNA-binding heavy metal response regulator	NC_004129 (Pseudomonas protegens Pf-5)	3e-56	55
205) Dda3937_02280   ( YP_003881463.1 )	two-component response regulator	NC_014500 (Dickeya dadantii 3937)	3e-56	52
206) Pfl01_3379   ( YP_349108.1 )	two component heavy metal response transcriptional regulator	NC_007492 (Pseudomonas fluorescens Pf0-1)	3e-56	52
207) czcR3   ( YP_008002278.1 )	transcriptional activator protein CzcR	NC_021237 (Pseudomonas fluorescens CHA0)	4e-56	56
208) PFL_5050   ( YP_262129.1 )	DNA-binding heavy metal response regulator	NC_004129 (Pseudomonas protegens Pf-5)	4e-56	56
209) Daci_1091   ( YP_001562121.1 )	two component heavy metal response transcriptional regulator	NC_010002 (Delftia acidovorans SPH-1)	4e-56	54
210) cusR   ( YP_006094925.1 )	two-component system response regulator	NC_017626 (Escherichia coli 042)	4e-56	52
211) cusR   ( YP_003227712.1 )	DNA-binding transcriptional activator CusR	NC_013361 (Escherichia coli 11368)	4e-56	52
212) cusR   ( YP_003220574.1 )	DNA-binding response regulator CusR in two-component regulatory system with CusS	NC_013353 (Escherichia coli 12009)	4e-56	52
213) O3M_18735   ( YP_006771373.1 )	DNA-binding transcriptional activator CusR	NC_018650 (Escherichia coli 2009EL-2050)	4e-56	52
214) O3O_06535   ( YP_006785564.1 )	DNA-binding transcriptional activator CusR	NC_018661 (Escherichia coli 2009EL-2071)	4e-56	52
215) O3K_18760   ( YP_006780424.1 )	DNA-binding transcriptional activator CusR	NC_018658 (Escherichia coli 2011C-3493)	4e-56	52
216) ECP_0602   ( YP_668529.1 )	DNA-binding transcriptional activator CusR	NC_008253 (Escherichia coli 536)	4e-56	52
217) cusR   ( YP_002401678.1 )	DNA-binding transcriptional activator CusR	NC_011748 (Escherichia coli 55989)	4e-56	52
218) cusR   ( YP_006104748.1 )	transcriptional regulatory protein CusR	NC_017631 (Escherichia coli ABU 83972)	4e-56	52
219) ylcA   ( YP_851707.1 )	CusR family transcriptional regulator	NC_008563 (Escherichia coli APEC O1)	4e-56	52
220) EcolC_3075   ( YP_001726026.1 )	DNA-binding transcriptional activator CusR	NC_010468 (Escherichia coli ATCC 8739)	4e-56	52
221) cusR   ( YP_003498339.1 )	DNA-binding response regulator in two-component regulatory system with CusS	NC_013941 (Escherichia coli CB9615)	4e-56	52
222) cusR   ( YP_006142692.1 )	DNA-binding response regulator in two-component regulatory system with CusS	NC_017646 (Escherichia coli CE10)	4e-56	52
223) cusR   ( NP_752588.1 )	DNA-binding transcriptional activator CusR	NC_004431 (Escherichia coli CFT073)	4e-56	52
224) cusR   ( YP_006152763.1 )	DNA-binding transcriptional activator CusR	NC_017652 (Escherichia coli clone D i14)	4e-56	52
225) cusR   ( YP_006147844.1 )	DNA-binding transcriptional activator CusR	NC_017651 (Escherichia coli clone D i2)	4e-56	52
226) EcDH1_3058   ( YP_006092975.1 )	two component heavy metal response transcriptional regulator, winged helix family	NC_017625 (Escherichia coli DH1)	4e-56	52
227) cusR   ( YP_006127940.1 )	DNA-binding response regulator in two-component regulatory system with CusS	NC_017638 (Escherichia coli DH1)	4e-56	52
228) cusR   ( YP_002328044.1 )	DNA-binding transcriptional activator CusR	NC_011601 (Escherichia coli E2348/69)	4e-56	52
229) cusR   ( YP_002269201.1 )	DNA-binding transcriptional activator CusR	NC_011353 (Escherichia coli EC4115)	4e-56	52
230) cusR   ( YP_002396609.1 )	DNA-binding transcriptional activator CusR	NC_011745 (Escherichia coli ED1a)	4e-56	52
231) ylcA   ( NP_286296.1 )	DNA-binding transcriptional activator CusR	NC_002655 (Escherichia coli EDL933)	4e-56	52
232) ETEC_0599   ( YP_006114188.1 )	two-component system response regulator	NC_017633 (Escherichia coli ETEC H10407)	4e-56	52
233) cusR   ( YP_001457381.1 )	DNA-binding transcriptional activator CusR	NC_009800 (Escherichia coli HS)	4e-56	52
234) cusR   ( YP_002406572.1 )	DNA-binding transcriptional activator CusR	NC_011750 (Escherichia coli IAI39)	4e-56	52
235) cusR   ( YP_006099819.1 )	transcriptional regulatory protein cusR	NC_017628 (Escherichia coli IHE3034)	4e-56	52
236) cusR   ( YP_001729470.1 )	DNA-binding transcriptional activator CusR	NC_010473 (Escherichia coli K-12)	4e-56	52
237) cusR   ( YP_001729571.1 )	DNA-binding transcriptional activator CusR	NC_010473 (Escherichia coli K-12)	4e-56	52
238) cusR   ( YP_002925644.1 )	DNA-binding transcriptional activator CusR	NC_012759 (Escherichia coli K-12)	4e-56	52
239) cusR   ( YP_007556133.1 )	DNA-binding response regulator in two-component regulatory system with CusS	NC_020518 (Escherichia coli K-12)	4e-56	52
240) cusR   ( YP_488858.1 )	DNA-binding response regulator in two-component regulatory system with CusS	NC_007779 (Escherichia coli K-12)	4e-56	52
241) cusR   ( NP_415103.1 )	DNA-binding response regulator in two-component regulatory system with CusS	NC_000913 (Escherichia coli K12)	4e-56	52
242) cusR   ( YP_002555465.1 )	Transcriptional regulatory protein cusR	NC_011993 (Escherichia coli LF82)	4e-56	52
243) cusR   ( YP_006137598.1 )	DNA-binding transcriptional activator protein	NC_017644 (Escherichia coli NA114)	4e-56	52
244) NRG857_02565   ( YP_006118877.1 )	DNA-binding transcriptional activator CusR	NC_017634 (Escherichia coli NRG 857C)	4e-56	52
245) ylcA   ( YP_006167603.1 )	Transcriptional regulatory protein cusR	NC_017663 (Escherichia coli P12b)	4e-56	52
246) cusR   ( YP_008570511.1 )	Transcriptional regulatory protein CusR	NC_022370 (Escherichia coli PMV-1)	4e-56	52
247) ECO55CA74_03580   ( YP_006157886.1 )	DNA-binding transcriptional activator CusR	NC_017656 (Escherichia coli RM12579)	4e-56	52
248) cusR   ( YP_002390424.1 )	DNA-binding transcriptional activator CusR	NC_011742 (Escherichia coli S88)	4e-56	52
249) ECs0609   ( NP_308636.1 )	CusR family transcriptional regulator	NC_002695 (Escherichia coli Sakai)	4e-56	52
250) ECSE_0635   ( YP_002291910.1 )	DNA-binding transcriptional activator CusR	NC_011415 (Escherichia coli SE11)	4e-56	52
251) ECSF_0501   ( YP_003348491.1 )	putative two-component response regulator	NC_013654 (Escherichia coli SE15)	4e-56	52
252) cusR   ( YP_001742686.1 )	DNA-binding transcriptional activator CusR	NC_010498 (Escherichia coli SMS-3-5)	4e-56	52
253) cusR   ( YP_003076573.1 )	DNA-binding transcriptional activator CusR	NC_013008 (Escherichia coli TW14359)	4e-56	52
254) UM146_14660   ( YP_006111807.1 )	DNA-binding transcriptional activator CusR	NC_017632 (Escherichia coli UM146)	4e-56	52
255) cusR   ( YP_002411422.1 )	DNA-binding transcriptional activator CusR	NC_011751 (Escherichia coli UMN026)	4e-56	52
256) irlR   ( YP_006132408.1 )	transcriptional activator protein IrlR	NC_017641 (Escherichia coli UMNK88)	4e-56	52
257) ylcA   ( YP_539602.1 )	DNA-binding transcriptional activator CusR	NC_007946 (Escherichia coli UTI89)	4e-56	52
258) CDCO157_0593   ( YP_006311449.1 )	DNA-binding transcriptional activator CusR	NC_017906 (Escherichia coli Xuzhou21)	4e-56	52
259) cusR   ( YP_002383646.1 )	DNA-binding transcriptional activator CusR	NC_011740 (Escherichia fergusonii ATCC 35469)	4e-56	52
260) SSON53_02810   ( YP_005455139.1 )	DNA-binding transcriptional activator CusR	NC_016822 (Shigella sonnei 53G)	4e-56	52
261) ylcA   ( YP_309526.1 )	DNA-binding transcriptional activator CusR	NC_007384 (Shigella sonnei Ss046)	4e-56	52
262) A458_21605   ( YP_006459955.1 )	DNA-binding response regulator CzrR	NC_018028 (Pseudomonas stutzeri CCUG 29243)	5e-56	53
263) Psest_0611   ( YP_007238842.1 )	heavy metal response regulator	NC_019936 (Pseudomonas stutzeri RCH2)	5e-56	53
264) ylcA   ( YP_688070.1 )	DNA-binding transcriptional activator CusR	NC_008258 (Shigella flexneri 8401)	1e-55	52
265) Alide_2741   ( YP_004127359.1 )	heavy metal response regulator	NC_014910 (Alicycliphilus denitrificans BC)	6e-56	59
266) copR1   ( YP_581920.1 )	regulator protein CopR	NC_007971 (Cupriavidus metallidurans CH34)	6e-56	58
267) cusR   ( YP_002870621.1 )	tw-component system, response regulator	NC_012660 (Pseudomonas fluorescens SBW25)	7e-56	57
268) PflA506_0940   ( YP_006322461.1 )	DNA-binding heavy metal response regulator	NC_017911 (Pseudomonas fluorescens A506)	7e-56	56
269) APECO78_06430   ( YP_007380463.1 )	DNA-binding transcriptional activator CusR	NC_020163 (Escherichia coli APEC O78)	7e-56	52
270) cusR   ( YP_002998373.1 )	cusR	NC_012892 (Escherichia coli BL21(DE3))	7e-56	52
271) cusR   ( YP_003053183.1 )	DNA-binding response regulator in two-component regulatory system with CusS	NC_012971 (Escherichia coli BL21(DE3))	7e-56	52
272) cusR   ( YP_001461733.1 )	DNA-binding transcriptional activator CusR	NC_009801 (Escherichia coli E24377A)	7e-56	52
273) ECBD_3091   ( YP_003037282.1 )	CusR family transcriptional regulator	NC_012947 (Escherichia coli Escherichia coli BL21-Gold(DE3)pLysS AG)	7e-56	52
274) cusR   ( YP_002386025.1 )	DNA-binding transcriptional activator CusR	NC_011741 (Escherichia coli IAI1)	7e-56	52
275) EKO11_3296   ( YP_005278941.1 )	two component heavy metal response transcriptional regulator, winged helix family	NC_016902 (Escherichia coli KO11FL)	7e-56	52
276) cusR   ( YP_006166481.1 )	DNA-binding transcriptional activator CusR	NC_017660 (Escherichia coli KO11FL)	7e-56	52
277) LY180_03085   ( YP_008563757.1 )	transcriptional regulator	NC_022364 (Escherichia coli LY180)	7e-56	52
278) cusR   ( YP_003043755.1 )	DNA-binding transcriptional activator CusR	NC_012967 (Escherichia coli REL606)	7e-56	52
279) cusR   ( YP_006123393.1 )	DNA-binding response regulator in two-component regulatory system with CusS	NC_017635 (Escherichia coli W)	7e-56	52
280) cusR   ( YP_006172073.1 )	DNA-binding transcriptional activator CusR	NC_017664 (Escherichia coli W)	7e-56	52
281) Pfl01_0202   ( YP_345935.1 )	two component heavy metal response transcriptional regulator	NC_007492 (Pseudomonas fluorescens Pf0-1)	8e-56	54
282) Entcl_3253   ( YP_003942783.1 )	two component heavy metal response transcriptional regulator, winged helix family	NC_014618 (Enterobacter cloacae SCF1)	8e-56	53
283) Dsui_2644   ( YP_005028835.1 )	heavy metal response regulator	NC_016616 (Dechlorosoma suillum PS)	1e-55	59
284) H045_01525   ( YP_007395877.1 )	DNA-binding heavy metal response regulator	NC_020209 (Pseudomonas poae RE*1-1-14)	1e-55	57
285) Q7S_06655   ( YP_005401142.1 )	two component heavy metal response transcriptional regulator, winged helix family protein	NC_017047 (Rahnella aquatilis HX2)	1e-55	56
286) Rahaq_1379   ( YP_004212129.1 )	two component heavy metal response transcriptional regulator, winged helix family	NC_015061 (Rahnella sp. Y9602)	1e-55	56
287) L483_32095   ( YP_008098152.1 )	transcriptional regulator	NC_021491 (Pseudomonas putida H8234)	1e-55	55
288) PputW619_5178   ( YP_001752023.1 )	two component heavy metal response transcriptional regulator	NC_010501 (Pseudomonas putida W619)	1e-55	55
289) NH44784_016901   ( YP_008028784.1 )	DNA-binding heavy metal response regulator	NC_021285 (Achromobacter xylosoxidans NH44784-1996)	1e-55	53
290) ECENHK_11170   ( YP_006578723.1 )	DNA-binding transcriptional activator CusR	NC_018405 (Enterobacter cloacae ENHKU01)	1e-55	52
291) czrR-2   ( YP_001173891.1 )	DNA-binding response regulator CzrR	NC_009434 (Pseudomonas stutzeri A1501)	1e-55	52
292) PputUW4_04493   ( YP_007031490.1 )	DNA-binding heavy metal response regulator	NC_019670 (Pseudomonas sp. UW4)	2e-55	56
293) Pfl01_4663   ( YP_350391.1 )	two component heavy metal response transcriptional regulator	NC_007492 (Pseudomonas fluorescens Pf0-1)	2e-55	55
294) CtCNB1_2473   ( YP_003278515.1 )	two component heavy metal response transcriptional regulator	NC_013446 (Comamonas testosteroni CNB-1)	2e-55	54
295) czrR   ( YP_004713610.1 )	DNA-binding response regulator CzrR	NC_015740 (Pseudomonas stutzeri ATCC 17588)	2e-55	52
296) czrR-2   ( YP_005940140.1 )	DNA-binding response regulator CzrR	NC_017532 (Pseudomonas stutzeri DSM 4166)	2e-55	52
297) Daci_1713   ( YP_001562741.1 )	two component heavy metal response transcriptional regulator	NC_010002 (Delftia acidovorans SPH-1)	2e-55	51
298) ST548_p5064   ( YP_007389534.1 )	Copper-sensing two-component system response regulator CusR	NC_020181 (Enterobacter aerogenes EA1509E)	2e-55	52
299) EAE_09990   ( YP_004592193.1 )	DNA-binding transcriptional activator CusR	NC_015663 (Enterobacter aerogenes KCTC 2190)	2e-55	52
300) cusR   ( YP_002240684.1 )	DNA-binding transcriptional activator CusR	NC_011283 (Klebsiella pneumoniae 342)	2e-55	52
301) Kvar_4536   ( YP_003441442.1 )	winged helix family two component transcriptional regulator	NC_013850 (Klebsiella variicola At-22)	2e-55	52
302) HEAR0604   ( YP_001098931.1 )	two-component system response regulator	NC_009138 (Herminiimonas arsenicoxydans )	3e-55	56
303) silR   ( YP_003212811.1 )	DNA-binding transcriptional activator CusR	NC_013285 (Cronobacter turicensis z3032)	3e-55	53
304) cusR   ( YP_003233121.1 )	DNA-binding response regulator CusR	NC_013364 (Escherichia coli 11128)	3e-55	52
305) silR   ( YP_006113807.1 )	DNA-binding response regulator transcriptional regulator	NC_017633 (Escherichia coli ETEC H10407)	4e-55	54
306) ESA_04238   ( YP_001440254.1 )	DNA-binding transcriptional activator CusR	NC_009778 (Cronobacter sakazakii ATCC BAA-894)	4e-55	53
307) cusR   ( YP_003602531.1 )	DNA-binding transcriptional activator CusR	NC_014107 (Enterobacter cloacae ATCC 13047)	4e-55	53
308) cusR   ( YP_003615370.1 )	DNA-binding transcriptional activator CusR	NC_014121 (Enterobacter cloacae ATCC 13047)	4e-55	53
309) O3M_01560   ( YP_006767993.1 )	DNA-binding transcriptional activator CusR	NC_018650 (Escherichia coli 2009EL-2050)	4e-55	53
310) O3O_24130   ( YP_006782100.1 )	DNA-binding transcriptional activator CusR	NC_018661 (Escherichia coli 2009EL-2071)	4e-55	53
311) O3K_01515   ( YP_006777035.1 )	DNA-binding transcriptional activator CusR	NC_018658 (Escherichia coli 2011C-3493)	4e-55	53
312) cusR   ( YP_002404852.1 )	DNA-binding transcriptional activator CusR	NC_011748 (Escherichia coli 55989)	4e-55	53
313) silR   ( YP_001481464.1 )	DNA-binding transcriptional activator CusR	NC_009838 (Escherichia coli APEC O1)	4e-55	53
314) silR   ( YP_001338559.1 )	DNA-binding transcriptional activator CusR	NC_009649 (Klebsiella pneumoniae subsp. pneumoniae MGH 78578)	4e-55	53
315) CFSAN002050_22100   ( YP_008262287.1 )	transcriptional regulator	NC_021818 (Salmonella enterica CFSAN002050)	4e-55	53
316) PputGB1_4369   ( YP_001670593.1 )	two component heavy metal response transcriptional regulator	NC_010322 (Pseudomonas putida GB-1)	4e-55	52
317) B479_21105   ( YP_007231054.1 )	two component heavy metal response transcriptional regulator	NC_019905 (Pseudomonas putida PC9)	4e-55	52
318) PPS_4210   ( YP_004703629.1 )	two component heavy metal response transcriptional regulator	NC_015733 (Pseudomonas putida S16)	4e-55	52
319) cusR   ( YP_005726142.1 )	putative 2-component transcriptional regulator	NC_017328 (Shigella flexneri 2002017)	4e-55	52
320) ylcA   ( NP_836192.1 )	DNA-binding transcriptional activator CusR	NC_004741 (Shigella flexneri 2457T)	4e-55	52
321) ylcA   ( NP_706418.1 )	DNA-binding transcriptional activator CusR	NC_004337 (Shigella flexneri 301)	4e-55	52
322) CSSP291_21158   ( YP_007442925.1 )	DNA-binding transcriptional activator CusR	NC_020261 (Cronobacter sakazakii Sp291)	5e-55	54
323) EcolC_3426   ( YP_001726370.1 )	DNA-binding transcriptional activator CusR	NC_010468 (Escherichia coli ATCC 8739)	5e-55	54
324) KPN2242_25411   ( YP_005957473.1 )	DNA-binding transcriptional activator CusR	NC_017541 (Klebsiella pneumoniae KCTC 2242)	5e-55	54
325) pK2044_00635   ( YP_001687957.1 )	DNA-binding transcriptional activator CusR	NC_006625 (Klebsiella pneumoniae NTUH-K2044)	5e-55	54
326) M495_16080   ( YP_008231153.1 )	transcriptional regulator	NC_021741 (Serratia liquefaciens ATCC 27592)	5e-55	53
327) Hsero_2484   ( YP_003775891.1 )	two component heavy metal response transcription regulator protein	NC_014323 (Herbaspirillum seropedicae SmR1)	6e-55	56
328) PSEEN0943   ( YP_606663.1 )	DNA-binding heavy metal response regulator	NC_008027 (Pseudomonas entomophila L48)	6e-55	55
329) N559_5301   ( YP_008415082.1 )	DNA-binding transcriptional activator CusR	NC_022078 (Klebsiella pneumoniae JM45)	6e-55	54
330) Shew_3258   ( YP_001095383.1 )	two component heavy metal response transcriptional regulator	NC_009092 (Shewanella loihica PV-4)	6e-55	52
331) czrR   ( YP_008112025.1 )	two-component response regulator CzrR	NC_021505 (Pseudomonas putida NBRC 14164)	6e-55	51
332) C380_05840   ( YP_006853519.1 )	two-component response regulator	NC_018708 (Acidovorax sp. KKS102)	7e-55	52
333) KPHS_05860   ( YP_005224886.1 )	transcriptional activator protein Irlr	NC_016845 (Klebsiella pneumoniae HS11286)	7e-55	52
334) N559_4558   ( YP_008427439.1 )	transcriptional activator protein Irlr	NC_022082 (Klebsiella pneumoniae JM45)	7e-55	52
335) KPN2242_01830   ( YP_005952855.1 )	DNA-binding transcriptional activator CusR	NC_017540 (Klebsiella pneumoniae KCTC 2242)	7e-55	52
336) KP1_0690   ( YP_002917605.1 )	DNA-binding transcriptional activator CusR	NC_012731 (Klebsiella pneumoniae NTUH-K2044)	7e-55	52
337) KPN_04740   ( YP_001338357.1 )	DNA-binding transcriptional activator CusR	NC_009648 (Klebsiella pneumoniae subsp. pneumoniae MGH 78578)	7e-55	52
338) L483_26250   ( YP_008096996.1 )	transcriptional regulator	NC_021491 (Pseudomonas putida H8234)	7e-55	51
339) Rfer_0422   ( YP_521707.1 )	two component heavy metal response transcriptional regulator	NC_007908 (Rhodoferax ferrireducens T118)	1e-54	56
340) PSPPH_1195   ( YP_273462.1 )	DNA-binding heavy metal response regulator	NC_005773 (Pseudomonas syringae 1448A)	1e-54	55
341) ENC_35520   ( YP_007846961.1 )	heavy metal response regulator	NC_021046 (Enterobacter cloacae NCTC 9394)	1e-54	53
342) silR   ( YP_006170599.1 )	DNA-binding response regulator in two-component regulatory system with CusS	NC_017663 (Escherichia coli P12b)	1e-54	53
343) czcR   ( YP_002870368.1 )	two-component system response regulator	NC_012660 (Pseudomonas fluorescens SBW25)	1e-54	53
344) PputGB1_0836   ( YP_001667082.1 )	two component heavy metal response transcriptional regulator	NC_010322 (Pseudomonas putida GB-1)	1e-54	53
345) L483_04030   ( YP_008092635.1 )	transcriptional regulator	NC_021491 (Pseudomonas putida H8234)	1e-54	53
346) PP4_44810   ( YP_008115518.1 )	two-component response regulator	NC_021505 (Pseudomonas putida NBRC 14164)	1e-54	53
347) CFSAN002069_14165   ( YP_008251611.1 )	transcriptional regulator	NC_021812 (Salmonella enterica CFSAN002069)	1e-54	53
348) Sputcn32_0258   ( YP_001181792.1 )	DNA-binding transcriptional activator CusR	NC_009438 (Shewanella putrefaciens CN-32)	1e-54	53
349) Alide_0227   ( YP_004124898.1 )	heavy metal response regulator	NC_014910 (Alicycliphilus denitrificans BC)	1e-54	52
350) CzrR   ( YP_609756.1 )	heavy-metal DNA-binding response regulator CzrR	NC_008027 (Pseudomonas entomophila L48)	1e-54	52
351) PSPPH_4828   ( YP_276924.1 )	DNA-binding heavy metal response regulator	NC_005773 (Pseudomonas syringae 1448A)	1e-54	51
352) Psyr_4800   ( YP_237865.1 )	heavy metal response regulator	NC_007005 (Pseudomonas syringae B728a)	1e-54	51
353) Ajs_2725   ( YP_986944.1 )	two component heavy metal response transcriptional regulator	NC_008782 (Acidovorax sp. JS42)	2e-54	57
354) CFU_1244   ( YP_004751899.1 )	DNA-binding heavy metal response regulator	NC_015856 (Collimonas fungivorans Ter331)	2e-54	55
355) Mpe_A1629   ( YP_001020826.1 )	two-component response regulator	NC_008825 (Methylibium petroleiphilum PM1)	2e-54	52
356) Shewana3_4296   ( YP_863811.1 )	DNA-binding transcriptional activator CusR	NC_008573 (Shewanella sp. ANA-3)	8e-55	53
357) PSPTO_0378   ( NP_790227.1 )	DNA-binding heavy metal response regulator	NC_004578 (Pseudomonas syringae DC3000)	8e-55	51
358) KPR_0803   ( YP_007989784.1 )	hypothetical protein	NC_021232 (Klebsiella pneumoniae SB3432)	9e-55	52
359) czcR   ( YP_006530947.1 )	DNA-binding response regulator CzrR	NC_018220 (Pseudomonas putida DOT-T1E)	9e-55	51
360) Pput_4283   ( YP_001269591.1 )	two component heavy metal response transcriptional regulator	NC_009512 (Pseudomonas putida F1)	9e-55	51
361) czrR-2   ( NP_743596.1 )	DNA-binding response regulator CzrR	NC_002947 (Pseudomonas putida KT2440)	9e-55	51
362) YSA_02770   ( YP_006385389.1 )	DNA-binding response regulator CzrR	NC_017986 (Pseudomonas putida ND6)	9e-55	51
363) czcR2   ( YP_586599.1 )	two component heavy metal response transcriptional regulator, winged helix family	NC_007974 (Cupriavidus metallidurans CH34)	2e-54	55
364) A3UG_11440   ( YP_006477724.1 )	DNA-binding transcriptional activator CusR	NC_018079 (Enterobacter cloacae SDM)	2e-54	52
365) czcR   ( YP_007029055.1 )	two component heavy metal response transcriptional regulator	NC_019670 (Pseudomonas sp. UW4)	2e-54	51
366) PPS_0855   ( YP_004700314.1 )	two component heavy metal response transcriptional regulator	NC_015733 (Pseudomonas putida S16)	3e-54	53
367) cusR   ( YP_004952072.1 )	transcriptional regulatory protein CusR	NC_016514 (Enterobacter cloacae EcWSU1)	3e-54	52
368) cusR   ( YP_006317682.1 )	transcriptional regulatory protein CusR	NC_017910 (Escherichia blattae DSM 4481)	3e-54	52
369) HYPDE_40408   ( YP_007916249.1 )	two component transcriptional regulator, winged helix family protein	NC_021172 (Hyphomicrobium denitrificans 1NES1)	3e-54	52
370) PFLU4171   ( YP_002873721.1 )	response regulatory protein	NC_012660 (Pseudomonas fluorescens SBW25)	3e-54	51
371) MDS_2489   ( YP_004380272.1 )	two component heavy metal response transcriptional regulator	NC_015410 (Pseudomonas mendocina NK-01)	4e-54	57
372) Pmen_2234   ( YP_001187725.1 )	two component heavy metal response transcriptional regulator	NC_009439 (Pseudomonas mendocina ymp)	4e-54	57
373) BN112_3880   ( YP_006969916.1 )	response regulatory protein	NC_019382 (Bordetella bronchiseptica 253)	4e-54	54
374) BN115_4219   ( YP_006902441.1 )	response regulatory protein	NC_018829 (Bordetella bronchiseptica MO149)	4e-54	54
375) BB4542   ( NP_891076.1 )	response regulatory protein	NC_002927 (Bordetella bronchiseptica RB50)	4e-54	54
376) Dda3937_00228   ( YP_003881005.1 )	DNA-binding heavy metal response regulator	NC_014500 (Dickeya dadantii 3937)	4e-54	54
377) PSPTO_1307   ( NP_791136.1 )	DNA-binding heavy metal response regulator	NC_004578 (Pseudomonas syringae DC3000)	4e-54	54
378) RORB6_15845   ( YP_007875402.1 )	DNA-binding transcriptional activator CusR	NC_021066 (Raoultella ornithinolytica B6)	4e-54	52
379) cusR   ( YP_003612460.1 )	two-component system, OmpR family, copper resistance phosphate	NC_014121 (Enterobacter cloacae ATCC 13047)	4e-54	51
380) PPS_5258   ( YP_004704665.1 )	two component heavy metal response transcriptional regulator	NC_015733 (Pseudomonas putida S16)	5e-54	56
381) PputW619_4391   ( YP_001751240.1 )	two component heavy metal response transcriptional regulator	NC_010501 (Pseudomonas putida W619)	5e-54	54
382) B479_04485   ( YP_007227756.1 )	two component heavy metal response transcriptional regulator	NC_019905 (Pseudomonas putida PC9)	5e-54	52
383) RORB6_12760   ( YP_007874785.1 )	two-component response regulator	NC_021066 (Raoultella ornithinolytica B6)	5e-54	51
384) Csal_0102   ( YP_572165.1 )	two component heavy metal response transcriptional regulator	NC_007963 (Chromohalobacter salexigens DSM 3043)	6e-54	58
385) PPS_5251   ( YP_004704658.1 )	DNA-binding heavy metal response regulator	NC_015733 (Pseudomonas putida S16)	6e-54	55
386) Psyr_1127   ( YP_234219.1 )	heavy metal response regulator	NC_007005 (Pseudomonas syringae B728a)	6e-54	54
387) Varpa_4082   ( YP_004156365.1 )	winged helix family two component heavy metal response transcriptional regulator	NC_014931 (Variovorax paradoxus EPS)	7e-54	54
388) H045_12115   ( YP_007397984.1 )	response regulatory protein	NC_020209 (Pseudomonas poae RE*1-1-14)	7e-54	51
389) HCH_03613   ( YP_434778.1 )	response regulator	NC_007645 (Hahella chejuensis KCTC 2396)	1e-53	57
390) irlR2   ( YP_003977180.1 )	transcriptional activator protein IrlR 2	NC_014640 (Achromobacter xylosoxidans A8)	1e-53	56
391) NH44784_009211   ( YP_008028022.1 )	DNA-binding heavy metal response regulator	NC_021285 (Achromobacter xylosoxidans NH44784-1996)	1e-53	56
392) PADK2_11845   ( YP_006482354.1 )	transcriptional activator protein IrlR 2	NC_018080 (Pseudomonas aeruginosa DK2)	1e-53	56
393) L483_16290   ( YP_008095038.1 )	transcriptional regulator	NC_021491 (Pseudomonas putida H8234)	1e-53	56
394) cusR   ( YP_006373605.1 )	two component response regulator	NC_017958 (Tistrella mobilis KA081020-065)	1e-53	56
395) Dd586_0224   ( YP_003331826.1 )	winged helix family two component transcriptional regulator	NC_013592 (Dickeya dadantii Ech586)	1e-53	53
396) T1E_4698   ( YP_006535319.1 )	DNA-binding heavy metal response regulator, puta	NC_018220 (Pseudomonas putida DOT-T1E)	8e-54	55
397) Pput_0061   ( YP_001265420.1 )	two component heavy metal response transcriptional regulator	NC_009512 (Pseudomonas putida F1)	8e-54	55
398) PputGB1_0061   ( YP_001666313.1 )	two component heavy metal response transcriptional regulator	NC_010322 (Pseudomonas putida GB-1)	8e-54	55
399) L483_16000   ( YP_008094980.1 )	transcriptional regulator	NC_021491 (Pseudomonas putida H8234)	8e-54	55
400) PP_0047   ( NP_742217.1 )	DNA-binding heavy metal response regulator	NC_002947 (Pseudomonas putida KT2440)	8e-54	55
401) PP4_00380   ( YP_008111075.1 )	putative two-component response regulator	NC_021505 (Pseudomonas putida NBRC 14164)	8e-54	55
402) YSA_04795   ( YP_006386478.1 )	DNA-binding heavy metal response regulator	NC_017986 (Pseudomonas putida ND6)	8e-54	55
403) B479_00550   ( YP_007226971.1 )	two component heavy metal response transcriptional regulator	NC_019905 (Pseudomonas putida PC9)	8e-54	55
404) PputW619_0064   ( YP_001746939.1 )	two component heavy metal response transcriptional regulator	NC_010501 (Pseudomonas putida W619)	8e-54	55
405) H045_00110   ( YP_007395594.1 )	two-component system response regulator	NC_020209 (Pseudomonas poae RE*1-1-14)	8e-54	53
406) Psyc_1596   ( YP_264878.1 )	two component heavy metal response transcriptional regulator	NC_007204 (Psychrobacter arcticus 273-4)	8e-54	50
407) Dtpsy_2201   ( YP_002553641.1 )	winged helix family two component heavy metal response transcriptional regulator	NC_011992 (Acidovorax ebreus TPSY)	9e-54	58
408) Daci_0451   ( YP_001561482.1 )	two component heavy metal response transcriptional regulator	NC_010002 (Delftia acidovorans SPH-1)	9e-54	56
409) Psest_1598   ( YP_007239778.1 )	heavy metal response regulator	NC_019936 (Pseudomonas stutzeri RCH2)	9e-54	54
410) copR   ( YP_008103936.1 )	two-component response regulator CopR	NC_021499 (Pseudomonas resinovorans NBRC 106553)	2e-53	56
411) A458_14240   ( YP_006458500.1 )	transcriptional activator CopR	NC_018028 (Pseudomonas stutzeri CCUG 29243)	2e-53	54
412) czcR   ( YP_008137576.1 )	transcriptional activator protein CzcR	NC_021591 (Serratia odorifera 4Rx13)	2e-53	54
413) M621_07680   ( YP_008158355.1 )	transcriptional regulator	NC_021659 (Serratia plymuthica S13)	2e-53	54
414) PSPA7_3892   ( YP_001349246.1 )	putative two-component response regulator	NC_009656 (Pseudomonas aeruginosa PA7)	2e-53	53
415) czcR5   ( YP_008002444.1 )	transcriptional activator protein CzcR	NC_021237 (Pseudomonas fluorescens CHA0)	2e-53	51
416) czcR   ( YP_262298.1 )	DNA-binding heavy metal response regulator	NC_004129 (Pseudomonas protegens Pf-5)	2e-53	51
417) czcR   ( YP_003773453.1 )	response regulator for cobalt/zinc/cadmium resistance transcription regulator protein	NC_014323 (Herbaspirillum seropedicae SmR1)	3e-53	57
418) Ser39006_1425   ( YP_008521807.1 )	two component heavy metal response transcriptional regulator, winged helix family	NC_022268 (Serratia sp. ATCC 39006)	3e-53	55
419) NH44784_019131   ( YP_008029006.1 )	DNA-binding heavy metal response regulator	NC_021285 (Achromobacter xylosoxidans NH44784-1996)	3e-53	53
420) BN117_4143   ( YP_006897881.1 )	response regulatory protein	NC_018828 (Bordetella parapertussis Bpp5)	3e-53	53
421) PSEBR_a2893   ( YP_004354198.1 )	two-component system, response regulator	NC_015379 (Pseudomonas brassicacearum NFM421)	3e-53	52
422) irlR4   ( YP_003980709.1 )	transcriptional activator protein IrlR 4	NC_014640 (Achromobacter xylosoxidans A8)	3e-53	51
423) Dd586_2641   ( YP_003334189.1 )	winged helix family two component transcriptional regulator	NC_013592 (Dickeya dadantii Ech586)	3e-53	51
424) CFU_0183   ( YP_004750844.1 )	DNA-binding heavy metal response regulator	NC_015856 (Collimonas fungivorans Ter331)	4e-53	54
425) PflA506_0682   ( YP_006322212.1 )	DNA-binding heavy metal response regulator	NC_017911 (Pseudomonas fluorescens A506)	4e-53	53
426) copR   ( YP_001633212.1 )	two-component response regulator	NC_010170 (Bordetella petrii DSM 12804)	4e-53	52
427) Neut_0040   ( YP_746295.1 )	two component heavy metal response transcriptional regulator, winged helix family protein	NC_008344 (Nitrosomonas eutropha C91)	4e-53	51
428) irlR   ( YP_786564.1 )	heavy metal sensing two-component sytem response regulator	NC_010645 (Bordetella avium 197N)	5e-53	54
429) C380_06225   ( YP_006853594.1 )	two-component response regulator	NC_018708 (Acidovorax sp. KKS102)	5e-53	52
430) PSF113_2884   ( YP_005208283.1 )	DNA-binding heavy metal response regulator	NC_016830 (Pseudomonas fluorescens F113)	5e-53	50
431) copR/cusR   ( YP_007553175.1 )	two-component heavy metal response transcriptional regulator, winged helix family	NC_020516 (Azoarcus sp. KH32C)	1e-52	58
432) czcR   ( YP_581787.1 )	regulatory protein CzcR	NC_007971 (Cupriavidus metallidurans CH34)	1e-52	55
433) G655_18030   ( YP_007710446.1 )	two-component response regulator	NC_020912 (Pseudomonas aeruginosa B136-33)	6e-53	53
434) PADK2_18540   ( YP_006483685.1 )	two-component response regulator	NC_018080 (Pseudomonas aeruginosa DK2)	6e-53	53
435) PLES_39771   ( YP_002441560.1 )	putative two-component response regulator	NC_011770 (Pseudomonas aeruginosa LESB58)	6e-53	53
436) PAM18_3694   ( YP_005976277.1 )	putative two-component response regulator	NC_017548 (Pseudomonas aeruginosa M18)	6e-53	53
437) NCGM2_2320   ( YP_005980563.1 )	putative two-component response regulator	NC_017549 (Pseudomonas aeruginosa NCGM2.S1)	6e-53	53
438) PA1437   ( NP_250128.1 )	two-component response regulator	NC_002516 (Pseudomonas aeruginosa PAO1)	6e-53	53
439) M062_07705   ( YP_008131986.1 )	transcriptional regulator	NC_021577 (Pseudomonas aeruginosa RP73)	6e-53	53
440) PA14_45880   ( YP_791815.1 )	two-component response regulator	NC_008463 (Pseudomonas aeruginosa UCBPP-PA14)	6e-53	53
441) Veis_0344   ( YP_995152.1 )	two component heavy metal response transcriptional regulator	NC_008786 (Verminephrobacter eiseniae EF01-2)	7e-53	54
442) copR   ( YP_070510.1 )	transcriptional activator	NC_006155 (Yersinia pseudotuberculosis IP 32953)	7e-53	49
443) YPTS_2050   ( YP_001872473.1 )	two component heavy metal response transcriptional regulator	NC_010634 (Yersinia pseudotuberculosis PB1/+)	7e-53	49
444) BYI23_D012050   ( YP_005044238.1 )	two component heavy metal response transcriptional regulator	NC_016626 (Burkholderia sp. YI23)	8e-53	53
445) Dd703_3722   ( YP_002989299.1 )	two component heavy metal response transcriptional regulator, winged helix family	NC_012880 (Dickeya dadantii Ech703)	8e-53	53
446) G655_25765   ( YP_007711983.1 )	two-component response regulator	NC_020912 (Pseudomonas aeruginosa B136-33)	9e-53	58
447) irlR   ( YP_793353.1 )	two-component response regulator	NC_008463 (Pseudomonas aeruginosa UCBPP-PA14)	9e-53	58
448) Varpa_4641   ( YP_004156915.1 )	winged helix family two component heavy metal response transcriptional regulator	NC_014931 (Variovorax paradoxus EPS)	9e-53	55
449) Ajs_1236   ( YP_985538.1 )	two component heavy metal response transcriptional regulator	NC_008782 (Acidovorax sp. JS42)	1e-52	58
450) irlR   ( YP_001350928.1 )	two-component response regulator	NC_009656 (Pseudomonas aeruginosa PA7)	1e-52	58
451) YpsIP31758_2084   ( YP_001401057.1 )	DNA-binding heavy metal response regulator	NC_009708 (Yersinia pseudotuberculosis IP 31758)	1e-52	51
452) copR   ( NP_993191.1 )	transcriptional activator	NC_005810 (Yersinia pestis 91001)	1e-52	49
453) A1122_16175   ( YP_005522876.1 )	transcriptional activator	NC_017168 (Yersinia pestis A1122)	1e-52	49
454) YPA_1383   ( YP_651295.1 )	transcriptional activator	NC_008150 (Yersinia pestis Antiqua)	1e-52	49
455) copR   ( YP_002346986.1 )	transcriptional activator	NC_003143 (Yersinia pestis CO92)	1e-52	49
456) copR   ( YP_005504976.1 )	transcriptional activator	NC_017154 (Yersinia pestis D106004)	1e-52	49
457) copR   ( YP_005508859.1 )	transcriptional activator	NC_017160 (Yersinia pestis D182038)	1e-52	49
458) copR   ( YP_005624181.1 )	transcriptional activator	NC_017265 (Yersinia pestis Harbin 35)	1e-52	49
459) y2307   ( NP_669615.1 )	two-component transcriptional regulator	NC_004088 (Yersinia pestis KIM)	1e-52	49
460) YPN_1481   ( YP_647411.1 )	transcriptional activator	NC_008149 (Yersinia pestis Nepal516)	1e-52	49
461) copR   ( YP_003567989.1 )	transcriptional activator	NC_014029 (Yersinia pestis Z176003)	1e-52	49
462) YPK_2192   ( YP_001720928.1 )	two component heavy metal response transcriptional regulator	NC_010465 (Yersinia pseudotuberculosis YPIII)	1e-52	49
463) M5M_02885   ( YP_006915522.1 )	response regulator receiver domain-containing protein	NC_018868 (Simiduia agarivorans SA1)	2e-52	55
464) PflA506_3479   ( YP_006324936.1 )	DNA-binding heavy metal response regulator	NC_017911 (Pseudomonas fluorescens A506)	2e-52	50
465) YpAngola_A2480   ( YP_001606897.1 )	DNA-binding heavy metal response regulator	NC_010159 (Yersinia pestis Angola)	2e-52	50
466) Pat9b_4502   ( YP_004119032.1 )	two component transcriptional regulator, winged helix family	NC_014840 (Pantoea sp. At-9b)	2e-52	49
467) Pcryo_0702   ( YP_579969.1 )	two component heavy metal response transcriptional regulator	NC_007969 (Psychrobacter cryohalolentis K5)	2e-52	49
468) SCD_n02252   ( YP_008547092.1 )	two component heavy metal response transcriptional regulator	NC_022357 (Sulfuricella denitrificans skB26)	2e-52	57
469) czcR2   ( YP_008000452.1 )	transcriptional activator protein CzcR	NC_021237 (Pseudomonas fluorescens CHA0)	2e-52	51
470) PFL_3147   ( YP_260253.1 )	DNA-binding heavy metal response regulator	NC_004129 (Pseudomonas protegens Pf-5)	2e-52	51
471) GU3_04980   ( YP_005091503.1 )	DNA-binding heavy metal response regulator	NC_016745 (Oceanimonas sp. GK1)	3e-52	56
472) Sinac_6762   ( YP_007206527.1 )	heavy metal response regulator	NC_019892 (Singulisphaera acidiphila DSM 18658)	3e-52	52
473) Bpet4609   ( YP_001633227.1 )	two-component response regulator	NC_010170 (Bordetella petrii DSM 12804)	3e-52	51
474) PsycPRwf_0705   ( YP_001279609.1 )	two component heavy metal response transcriptional regulator	NC_009524 (Psychrobacter sp. PRwf-1)	3e-52	48
475) cusR   ( YP_002871217.1 )	heavy metal two component system, response regulator	NC_012660 (Pseudomonas fluorescens SBW25)	4e-52	57
476) NH8B_2345   ( YP_004847573.1 )	two component heavy metal response transcriptional regulator	NC_016002 (Pseudogulbenkiania sp. NH8B)	4e-52	55
477) PSYCG_04030   ( YP_008162680.1 )	transcriptional regulator	NC_021661 (Psychrobacter sp. G)	4e-52	49
478) PSPA7_2348   ( YP_001347715.1 )	putative two-component response regulator	NC_009656 (Pseudomonas aeruginosa PA7)	6e-52	56
479) czcR   ( YP_002140403.1 )	winged-helix heavy metal transcriptional response regulator	NC_011146 (Geobacter bemidjiensis Bem)	6e-52	53
480) L483_15740   ( YP_008094928.1 )	transcriptional regulator	NC_021491 (Pseudomonas putida H8234)	7e-52	55
481) HNE_2188   ( YP_760884.1 )	DNA-binding heavy metal response regulator	NC_008358 (Hyphomonas neptunium ATCC 15444)	7e-52	53
482) H650_10010   ( YP_008107823.1 )	transcriptional regulator	NC_021500 (Enterobacter sp. R4-368)	7e-52	49
483) cinR   ( YP_007030498.1 )	two component heavy metal response transcriptional regulator	NC_019670 (Pseudomonas sp. UW4)	1e-51	55
484) GM18_4078   ( YP_004200769.1 )	two component heavy metal response transcriptional regulator, winged helix family	NC_014973 (Geobacter sp. M18)	1e-51	53
485) G655_10825   ( YP_007709012.1 )	two-component response regulator, CopR	NC_020912 (Pseudomonas aeruginosa B136-33)	2e-51	56
486) PADK2_10370   ( YP_006482063.1 )	two-component response regulator, CopR	NC_018080 (Pseudomonas aeruginosa DK2)	2e-51	56
487) copR   ( YP_002439866.1 )	two-component response regulator, CopR	NC_011770 (Pseudomonas aeruginosa LESB58)	2e-51	56
488) copR   ( YP_005974739.1 )	two-component response regulator, CopR	NC_017548 (Pseudomonas aeruginosa M18)	2e-51	56
489) copR   ( YP_005982129.1 )	putative two-component response regulator	NC_017549 (Pseudomonas aeruginosa NCGM2.S1)	2e-51	56
490) copR   ( NP_251499.1 )	two-component response regulator, CopR	NC_002516 (Pseudomonas aeruginosa PAO1)	2e-51	56
491) M062_15015   ( YP_008133430.1 )	transcriptional regulator	NC_021577 (Pseudomonas aeruginosa RP73)	2e-51	56
492) copR   ( YP_007999305.1 )	transcriptional activator protein CopR	NC_021237 (Pseudomonas fluorescens CHA0)	2e-51	55
493) GM21_3720   ( YP_003023497.1 )	two component heavy metal response transcriptional regulator, winged helix family	NC_012918 (Geobacter sp. M21)	2e-51	54
494) ACMV_P1_00370   ( YP_004276975.1 )	two-component response regulator	NC_015178 (Acidiphilium multivorum AIU301)	2e-51	52
495) copR   ( YP_790370.1 )	two-component response regulator	NC_008463 (Pseudomonas aeruginosa UCBPP-PA14)	3e-51	56
496) G655_12410   ( YP_007709327.1 )	two-component response regulator	NC_020912 (Pseudomonas aeruginosa B136-33)	3e-51	51
497) PADK2_12630   ( YP_006482509.1 )	two-component response regulator	NC_018080 (Pseudomonas aeruginosa DK2)	3e-51	51
498) PLES_27721   ( YP_002440366.1 )	putative two-component response regulator	NC_011770 (Pseudomonas aeruginosa LESB58)	3e-51	51
499) PAM18_2516   ( YP_005975101.1 )	putative two-component response regulator	NC_017548 (Pseudomonas aeruginosa M18)	3e-51	51
500) czrR   ( YP_005981761.1 )	putative two-component response regulator	NC_017549 (Pseudomonas aeruginosa NCGM2.S1)	3e-51	51
501) PSPA7_2714   ( YP_001348074.1 )	putative two-component response regulator	NC_009656 (Pseudomonas aeruginosa PA7)	3e-51	51
502) PA2523   ( NP_251213.1 )	two-component response regulator	NC_002516 (Pseudomonas aeruginosa PAO1)	3e-51	51
503) M062_13115   ( YP_008133056.1 )	transcriptional regulator	NC_021577 (Pseudomonas aeruginosa RP73)	3e-51	51
504) czrR   ( YP_790715.1 )	two-component response regulator	NC_008463 (Pseudomonas aeruginosa UCBPP-PA14)	3e-51	51
505) agrR   ( YP_583899.1 )	DNA-binding response regulator in two-component regulatory system with AgrS	NC_007973 (Cupriavidus metallidurans CH34)	4e-51	57
506) A458_21440   ( YP_006459924.1 )	transcriptional activator CopR	NC_018028 (Pseudomonas stutzeri CCUG 29243)	4e-51	56
507) irlR1   ( YP_003976567.1 )	transcriptional activator protein IrlR 1	NC_014640 (Achromobacter xylosoxidans A8)	5e-51	53
508) Acry_3106   ( YP_001219877.1 )	two component heavy metal response transcriptional regulator	NC_009467 (Acidiphilium cryptum JF-5)	8e-51	52
509) H681_15505   ( YP_007658509.1 )	two-component response regulator, CopR	NC_020829 (Pseudomonas denitrificans ATCC 13867)	2e-50	54
510) copR   ( YP_259084.1 )	DNA-binding copper response regulator	NC_004129 (Pseudomonas protegens Pf-5)	2e-50	54
511) D781_3623   ( YP_007346012.1 )	heavy metal response regulator	NC_020064 (Serratia marcescens FGI94)	3e-50	55
512) Spro_1498   ( YP_001477730.1 )	two component heavy metal response transcriptional regulator	NC_009832 (Serratia proteamaculans 568)	4e-50	53
513) copR   ( YP_004715066.1 )	transcriptional activator CopR	NC_015740 (Pseudomonas stutzeri ATCC 17588)	1e-49	53
514) copR   ( YP_005939454.1 )	transcriptional activator CopR	NC_017532 (Pseudomonas stutzeri DSM 4166)	1e-49	53
515) Tthe_1628   ( YP_003852221.1 )	transcriptional regulator	NC_014410 (Thermoanaerobacterium thermosaccharolyticum DSM 571)	1e-49	47
516) PputW619_1675   ( YP_001748549.1 )	two component heavy metal response transcriptional regulator	NC_010501 (Pseudomonas putida W619)	6e-50	53
517) Tbd_1749   ( YP_315507.1 )	two component heavy metal response transcriptional regulator	NC_007404 (Thiobacillus denitrificans ATCC 25259)	6e-50	53
518) ebA2024   ( YP_158149.1 )	two component response regulator	NC_006513 (Aromatoleum aromaticum EbN1)	7e-50	57
519) cusR   ( YP_005209356.1 )	protein CusR	NC_016830 (Pseudomonas fluorescens F113)	7e-50	54
520) SMWW4_v1c14840   ( YP_007405307.1 )	two component heavy metal response transcriptional regulator	NC_020211 (Serratia marcescens WW4)	7e-50	53
521) Ajs_1461   ( YP_985746.1 )	two component heavy metal response transcriptional regulator	NC_008782 (Acidovorax sp. JS42)	8e-50	61
522) M495_07050   ( YP_008229365.1 )	transcriptional regulator	NC_021741 (Serratia liquefaciens ATCC 27592)	9e-50	54
523) GU3_10755   ( YP_005092657.1 )	two component heavy metal response transcriptional regulator, winged helix family protein	NC_016745 (Oceanimonas sp. GK1)	2e-49	55
524) copR   ( YP_001007213.1 )	transcriptional activator	NC_008800 (Yersinia enterocolitica 8081)	2e-49	51
525) HDN1F_00360   ( YP_003809286.1 )	heavy metal response regulator	NC_014366 (gamma proteobacterium HdN1)	2e-49	55
526) PSEBR_a1770   ( YP_004352985.1 )	OmpR family response regulator	NC_015379 (Pseudomonas brassicacearum NFM421)	2e-49	54
527) PADK2_25915   ( YP_006485148.1 )	two-component response regulator	NC_018080 (Pseudomonas aeruginosa DK2)	3e-49	57
528) irlR   ( YP_002442849.1 )	two-component response regulator	NC_011770 (Pseudomonas aeruginosa LESB58)	3e-49	57
529) irlR   ( YP_005977579.1 )	two-component response regulator	NC_017548 (Pseudomonas aeruginosa M18)	3e-49	57
530) irlR   ( YP_005978913.1 )	two-component response regulator	NC_017549 (Pseudomonas aeruginosa NCGM2.S1)	3e-49	57
531) irlR   ( NP_253572.1 )	two-component response regulator	NC_002516 (Pseudomonas aeruginosa PAO1)	3e-49	57
532) M062_25775   ( YP_008135535.1 )	transcriptional regulator	NC_021577 (Pseudomonas aeruginosa RP73)	3e-49	57
533) H681_11850   ( YP_007657780.1 )	two component heavy metal response transcriptional regulator	NC_020829 (Pseudomonas denitrificans ATCC 13867)	3e-49	55
534) BurJV3_2171   ( YP_004792720.1 )	two component heavy metal response winged helix family transcriptional regulator	NC_015947 (Stenotrophomonas maltophilia JV3)	3e-49	53
535) Thethe_01629   ( YP_007298962.1 )	response regulator with CheY-like receiver domain and winged-helix DNA-binding domain	NC_019970 (Thermoanaerobacterium thermosaccharolyticum M0795)	3e-49	46
536) Glaag_4444   ( YP_004436624.1 )	two component heavy metal response transcriptional regulator, winged helix family	NC_015498 (Glaciecola sp. 4H-3-7+YE-5)	4e-49	53
537) Bmul_6295   ( YP_001573748.1 )	two component heavy metal response transcriptional regulator	NC_010070 (Burkholderia multivorans ATCC 17616)	4e-49	52
538) BMULJ_06267   ( YP_001942044.1 )	OmpR family two-component system response regulator	NC_010802 (Burkholderia multivorans ATCC 17616)	4e-49	52
539) RORB6_07810   ( YP_007873805.1 )	two component heavy metal response transcriptional regulator	NC_021066 (Raoultella ornithinolytica B6)	4e-49	50
540) Alide2_2186   ( YP_004388073.1 )	two component heavy metal response transcriptional regulator	NC_015422 (Alicycliphilus denitrificans K601)	5e-49	58
541) KOX_02230   ( YP_005016426.1 )	two component heavy metal response transcriptional regulator	NC_016612 (Klebsiella oxytoca KCTC 1686)	5e-49	50
542) EC55989_3902   ( YP_002404839.1 )	Transcriptional regulatory protein pcoR	NC_011748 (Escherichia coli 55989)	6e-49	53
543) A225_4890   ( YP_006500563.1 )	DNA-binding heavy metal response regulator	NC_018106 (Klebsiella oxytoca E718)	6e-49	51
544) L483_08035   ( YP_008093412.1 )	transcriptional regulator	NC_021491 (Pseudomonas putida H8234)	7e-49	53
545) copR   ( YP_008114727.1 )	two-component response regulator CopR	NC_021505 (Pseudomonas putida NBRC 14164)	7e-49	53
546) pcoR   ( YP_003212795.1 )	Transcriptional regulatory protein pcoR	NC_013285 (Cronobacter turicensis z3032)	7e-49	52
547) copR   ( YP_003741937.1 )	transcriptional activator	NC_014306 (Erwinia billingiae Eb661)	7e-49	48
548) PSEEN3704   ( YP_609212.1 )	DNA-binding heavy metal response regulator	NC_008027 (Pseudomonas entomophila L48)	8e-49	53
549) Psest_0581   ( YP_007238815.1 )	two component heavy metal response transcriptional regulator, winged helix family	NC_019936 (Pseudomonas stutzeri RCH2)	9e-49	54
550) ESA_04253   ( YP_001440269.1 )	hypothetical protein	NC_009778 (Cronobacter sakazakii ATCC BAA-894)	1e-48	54
551) pcoR   ( YP_003602511.1 )	two component heavy metal response transcriptional regulator	NC_014107 (Enterobacter cloacae ATCC 13047)	1e-48	54
552) pcoR   ( YP_003615352.1 )	two-component system, OmpR family, copper resistance phosphate regulon response regulator CusR	NC_014121 (Enterobacter cloacae ATCC 13047)	1e-48	54
553) O3M_01635   ( YP_006768008.1 )	transcriptional regulator PcoR	NC_018650 (Escherichia coli 2009EL-2050)	1e-48	54
554) O3O_24055   ( YP_006782115.1 )	transcriptional regulator PcoR	NC_018661 (Escherichia coli 2009EL-2071)	1e-48	54
555) O3K_01590   ( YP_006777050.1 )	transcriptional regulator PcoR	NC_018658 (Escherichia coli 2011C-3493)	1e-48	54
556) pcoR   ( YP_001481477.1 )	PcoR	NC_009838 (Escherichia coli APEC O1)	1e-48	54
557) EcolC_3412   ( YP_001726356.1 )	two component heavy metal response transcriptional regulator	NC_010468 (Escherichia coli ATCC 8739)	1e-48	54
558) ETEC_0235   ( YP_006113824.1 )	putative transcriptional regulatory protein PcoR	NC_017633 (Escherichia coli ETEC H10407)	1e-48	54
559) N559_5288   ( YP_008415069.1 )	Transcriptional regulatory protein pcoR	NC_022078 (Klebsiella pneumoniae JM45)	1e-48	54
560) KPN2242_25496   ( YP_005957488.1 )	Transcriptional regulatory protein pcoR	NC_017541 (Klebsiella pneumoniae KCTC 2242)	1e-48	54
561) pK2044_00560   ( YP_001687942.1 )	PcoR	NC_006625 (Klebsiella pneumoniae NTUH-K2044)	1e-48	54
562) pcoR   ( YP_001338546.1 )	transcriptional regulatory protein PcoR	NC_009649 (Klebsiella pneumoniae subsp. pneumoniae MGH 78578)	1e-48	54
563) CFSAN002050_22025   ( YP_008262272.1 )	transcriptional regulator	NC_021818 (Salmonella enterica CFSAN002050)	1e-48	54
564) CFSAN002069_14240   ( YP_008251626.1 )	transcriptional regulator	NC_021812 (Salmonella enterica CFSAN002069)	1e-48	54
565) copR   ( YP_006531882.1 )	two component heavy metal response	NC_018220 (Pseudomonas putida DOT-T1E)	1e-48	53
566) YSA_01465   ( YP_006384685.1 )	two component heavy metal response transcriptional regulator	NC_017986 (Pseudomonas putida ND6)	1e-48	53
567) B479_08415   ( YP_007228538.1 )	two component heavy metal response transcriptional regulator	NC_019905 (Pseudomonas putida PC9)	1e-48	53
568) PPS_1726   ( YP_004701177.1 )	two component heavy metal response transcriptional regulator	NC_015733 (Pseudomonas putida S16)	1e-48	53
569) PST_2712   ( YP_001173204.1 )	transcriptional activator CopR	NC_009434 (Pseudomonas stutzeri A1501)	1e-48	53
570) ABAYE1340   ( YP_001713256.1 )	two component heavy metal response transcriptional regulator	NC_010410 (Acinetobacter baumannii AYE)	1e-48	50
571) Thexy_1114   ( YP_004470819.1 )	two component transcriptional regulator, winged helix family	NC_015555 (Thermoanaerobacterium xylanolyticum LX-11)	1e-48	47
572) AOLE_06020   ( YP_003731472.1 )	putative two component heavy metal response transcriptional regulator	NC_014259 (Acinetobacter oleivorans DR1)	2e-48	50
573) AB57_2551   ( YP_002319895.1 )	two-component heavy metal response regulator protein	NC_011586 (Acinetobacter baumannii AB0057)	2e-48	50
574) irlR   ( YP_002325153.1 )	transcriptional activator protein irlR	NC_011595 (Acinetobacter baumannii AB307-0294)	2e-48	50
575) irlR   ( YP_004995982.1 )	two component heavy metal response transcriptional regulator, winged helix family	NC_016603 (Acinetobacter calcoaceticus PHEA-2)	2e-48	50
576) B479_00465   ( YP_007226954.1 )	two component heavy metal response transcriptional regulator	NC_019905 (Pseudomonas putida PC9)	3e-48	52
577) T1E_2811   ( YP_006533444.1 )	DNA-binding response regulator CzrR	NC_018220 (Pseudomonas putida DOT-T1E)	4e-48	51
578) Pput_0043   ( YP_001265402.1 )	two component heavy metal response transcriptional regulator	NC_009512 (Pseudomonas putida F1)	4e-48	51
579) PputGB1_0043   ( YP_001666295.1 )	two component heavy metal response transcriptional regulator	NC_010322 (Pseudomonas putida GB-1)	4e-48	51
580) czrR-1   ( NP_742199.1 )	DNA-binding response regulator CzrR	NC_002947 (Pseudomonas putida KT2440)	4e-48	51
581) czrR   ( YP_008111058.1 )	two-component response regulator CzrR	NC_021505 (Pseudomonas putida NBRC 14164)	4e-48	51
582) PputW619_0046   ( YP_001746921.1 )	two component heavy metal response transcriptional regulator	NC_010501 (Pseudomonas putida W619)	4e-48	51
583) PPUBIRD1_3496   ( YP_005931294.1 )	Two component heavy metal response transcriptional regulator	NC_017530 (Pseudomonas putida BIRD-1)	5e-48	53
584) Pput_3584   ( YP_001268892.1 )	two component heavy metal response transcriptional regulator	NC_009512 (Pseudomonas putida F1)	5e-48	53
585) PP_2158   ( NP_744307.1 )	two component heavy metal response transcriptional regulator	NC_002947 (Pseudomonas putida KT2440)	5e-48	53
586) L483_16080   ( YP_008094996.1 )	transcriptional regulator	NC_021491 (Pseudomonas putida H8234)	5e-48	51
587) BJAB0715_02598   ( YP_008217746.1 )	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain protein	NC_021733 (Acinetobacter baumannii BJAB0715)	5e-48	50
588) ompR   ( YP_004038834.1 )	two component heavy metal response transcriptional regulator, winged helix family	NC_014733 (Methylovorus sp. MP688)	7e-48	54
589) czcR   ( YP_006719491.1 )	winged-helix heavy metal transcriptional response regulator	NC_007517 (Geobacter metallireducens GS-15)	1e-47	57
590) PputGB1_1699   ( YP_001667938.1 )	two component heavy metal response transcriptional regulator	NC_010322 (Pseudomonas putida GB-1)	1e-47	53
591) DSC_01180   ( YP_004928930.1 )	DNA-binding heavy metal response regulator	NC_016147 (Pseudoxanthomonas spadix BD-a59)	1e-47	53
592) Dhaf_2231   ( YP_002458700.1 )	transcriptional regulator	NC_011830 (Desulfitobacterium hafniense DCB-2)	9e-48	48
593) Msip34_0398   ( YP_003050173.1 )	two component heavy metal response transcriptional regulator, winged helix family	NC_012969 (Methylovorus glucosetrophus SIP3-4)	2e-47	57
594) copR   ( YP_001098874.1 )	response regulator in two-component regulatory system with CusS, regulation of copper resistance	NC_009138 (Herminiimonas arsenicoxydans )	2e-47	55
595) NT01EI_2120   ( YP_002933531.1 )	transcriptional regulatory protein CusR, putative	NC_012779 (Edwardsiella ictaluri 93-146)	2e-47	54
596) ETAC_07645   ( YP_007629010.1 )	DNA-binding transcriptional activator CusR	NC_020796 (Edwardsiella tarda C07-087)	2e-47	53
597) DSY1143   ( YP_517376.1 )	hypothetical protein	NC_007907 (Desulfitobacterium hafniense Y51)	2e-47	48
598) BN112_3951   ( YP_006969987.1 )	two-component response regulator	NC_019382 (Bordetella bronchiseptica 253)	3e-47	53
599) BN115_4147   ( YP_006902369.1 )	two-component response regulator	NC_018829 (Bordetella bronchiseptica MO149)	3e-47	53
600) BB4471   ( NP_891005.1 )	two-component response regulator	NC_002927 (Bordetella bronchiseptica RB50)	3e-47	53
601) BPP3998   ( NP_886144.1 )	two-component response regulator	NC_002928 (Bordetella parapertussis 12822)	3e-47	53
602) BN117_4072   ( YP_006897812.1 )	two-component response regulator	NC_018828 (Bordetella parapertussis Bpp5)	3e-47	53
603) copR   ( YP_934449.1 )	two component response regulator	NC_008702 (Azoarcus sp. BH72)	4e-47	59
604) ylcA   ( YP_003295715.1 )	DNA-binding response regulator in two-component regulatory system with CusS	NC_013508 (Edwardsiella tarda EIB202)	4e-47	53
605) cusR   ( YP_005699105.1 )	Copper-sensing two-component system response regulator CusR	NC_017309 (Edwardsiella tarda FL6-60)	4e-47	53
606) Hipma_0180   ( YP_004339218.1 )	winged helix family two component transcriptional regulator	NC_015318 (Hippea maritima DSM 10411)	5e-47	44
607) irlR [H]   ( YP_007216262.1 )	DNA-binding heavy metal response regulator	NC_019902 (Thioalkalivibrio nitratireducens DSM 14787)	7e-47	58
608) copR1   ( YP_001352484.1 )	response regulator of copper sensing system	NC_009659 (Janthinobacterium sp. Marseille)	8e-47	58
609) Desde_1778   ( YP_006429967.1 )	response regulator with CheY-like receiver domain and winged-helix DNA-binding domain	NC_018017 (Desulfitobacterium dehalogenans ATCC 51507)	8e-47	47
610) irlR6   ( YP_003982109.1 )	transcriptional activator protein IrlR 6	NC_014640 (Achromobacter xylosoxidans A8)	1e-46	49
611) DP0600   ( YP_064336.1 )	Pho family two-component response regulator	NC_006138 (Desulfotalea psychrophila LSv54)	1e-46	48
612) Theba_1302   ( YP_006346233.1 )	response regulator with CheY-like receiver domain and winged-helix DNA-binding domain	NC_017934 (Mesotoga prima MesG1.Ag.4.2)	1e-46	47
613) DMR_45900   ( YP_002955967.1 )	OmpR family two-component response regulator	NC_012796 (Desulfovibrio magneticus RS-1)	1e-46	46
614) copR   ( YP_006031605.1 )	response regulator in two-component regulatory system with cops, regulation of copper resistance	NC_017575 (Ralstonia solanacearum Po82)	2e-46	58
615) Alvin_0277   ( YP_003442272.1 )	winged helix family two component transcriptional regulator	NC_013851 (Allochromatium vinosum DSM 180)	2e-46	49
616) AZOBR_150105   ( YP_005032067.1 )	two-component transcriptional regulator involved in heavy-metal (Cu/Zn) homeostasis	NC_016617 (Azospirillum brasilense Sp245)	2e-46	49
617) Desmer_3571   ( YP_006623282.1 )	response regulator with CheY-like receiver domain and winged-helix DNA-binding domain	NC_018515 (Desulfosporosinus meridiei DSM 13257)	2e-46	48
618) czcR1   ( YP_001353451.1 )	heavy metal response regulator	NC_009659 (Janthinobacterium sp. Marseille)	2e-46	46
619) copR2   ( YP_587800.1 )	DNA-binding response regulator in two-component regulatory system with CopS	NC_007974 (Cupriavidus metallidurans CH34)	3e-46	59
620) Dsui_1068   ( YP_005027311.1 )	heavy metal response regulator	NC_016616 (Dechlorosoma suillum PS)	3e-46	59
621) PPS_5240   ( YP_004704647.1 )	DNA-binding response regulator CzrR	NC_015733 (Pseudomonas putida S16)	3e-46	52
622) OmpR3   ( NP_622667.1 )	response regulator	NC_003869 (Thermoanaerobacter tengcongensis MB4)	3e-46	44
623) mma_0023   ( YP_001351713.1 )	two-components system response regulator	NC_009659 (Janthinobacterium sp. Marseille)	4e-46	52
624) YSA_04750   ( YP_006386457.1 )	DNA-binding response regulator CzrR	NC_017986 (Pseudomonas putida ND6)	4e-46	52
625) YE105_C1210   ( YP_004297409.1 )	transcriptional activator	NC_015224 (Yersinia enterocolitica 105.5R(r))	4e-46	49
626) AZOLI_0984   ( YP_005038558.1 )	Two-component transcriptional regulator involved in heavy-metal (Cu/Zn) homeostasis	NC_016622 (Azospirillum lipoferum 4B)	5e-46	48
627) BN118_0523   ( YP_006625263.1 )	two-component response regulator	NC_018518 (Bordetella pertussis 18323)	6e-46	53
628) BPTD_0155   ( YP_005588433.1 )	two-component response regulator	NC_017223 (Bordetella pertussis CS)	6e-46	53
629) BP0158   ( NP_879051.1 )	two-component response regulator	NC_002929 (Bordetella pertussis Tohama I)	6e-46	53
630) Bphy_6519   ( YP_001862593.1 )	two component heavy metal response transcriptional regulator	NC_010625 (Burkholderia phymatum STM815)	7e-46	50
631) Rpic12D_5335   ( YP_002973803.1 )	two component heavy metal response transcriptional regulator, winged helix family	NC_012849 (Ralstonia pickettii 12D)	8e-46	59
632) copR   ( YP_003749519.1 )	response regulator in two-component regulatory system with CopS, regulation of copper resistance	NC_014310 (Ralstonia solanacearum PSI07)	1e-45	60
633) GM18_0625   ( YP_004197382.1 )	two component heavy metal response transcriptional regulator, winged helix family	NC_014973 (Geobacter sp. M18)	1e-45	50
634) cusR   ( YP_002140254.1 )	heavy metal transcriptional response regulator CusR	NC_011146 (Geobacter bemidjiensis Bem)	1e-45	49
635) GM21_3531   ( YP_003023310.1 )	transcriptional regulator	NC_012918 (Geobacter sp. M21)	1e-45	49
636) Desaci_0309   ( YP_006464713.1 )	response regulator with CheY-like receiver domain and winged-helix DNA-binding domain	NC_018068 (Desulfosporosinus acidiphilus SJ4)	1e-45	48
637) STAUR_5903   ( YP_003955491.1 )	two-component response regulator	NC_014623 (Stigmatella aurantiaca DW4/3-1)	1e-45	48
638) SULAZ_0662   ( YP_002728647.1 )	transcriptional activator protein CopR	NC_012438 (Sulfurihydrogenibium azorense Az-Fu1)	2e-45	45
639) Acife_2136   ( YP_004784577.1 )	two component heavy metal response winged helix family transcriptional regulator	NC_015942 (Acidithiobacillus ferrivorans SS3)	2e-45	50
640) Alide2_2754   ( YP_004388622.1 )	two component heavy metal response transcriptional regulator	NC_015422 (Alicycliphilus denitrificans K601)	4e-45	60
641) AZL_010820   ( YP_003448264.1 )	two-component response regulator	NC_013854 (Azospirillum sp. B510)	4e-45	48
642) cusR   ( YP_006504821.1 )	DNA-binding response regulator in two-component regulatory system with CusS	NC_018139 (Legionella pneumophila Lorraine)	5e-45	46
643) SYO3AOP1_0130   ( YP_001930330.1 )	winged helix family two component transcriptional regulator	NC_010730 (Sulfurihydrogenibium sp. YO3AOP1)	6e-45	46
644) Psyr_3374   ( YP_236444.1 )	heavy metal response regulator	NC_007005 (Pseudomonas syringae B728a)	1e-44	56
645) HYPDE_39203   ( YP_007916009.1 )	winged helix family two component transcriptional regulator	NC_021172 (Hyphomicrobium denitrificans 1NES1)	1e-44	46
646) LPC_2578   ( YP_001251839.1 )	two component response regulator	NC_009494 (Legionella pneumophila Corby)	1e-44	46
647) HP15_3484   ( YP_005887176.1 )	DNA-binding response regulator	NC_017506 (Marinobacter adhaerens HP15)	1e-44	43
648) ompR   ( YP_003618003.1 )	two-component system, OmpR family, copper resistance phosphate regulon response regulator CusR	NC_014125 (Legionella pneumophila 2300/99 Alcoy)	8e-45	46
649) lp12_0724   ( YP_005185094.1 )	two component response regulator	NC_016811 (Legionella pneumophila ATCC 43290)	8e-45	46
650) lpp0781   ( YP_123111.1 )	hypothetical protein	NC_006368 (Legionella pneumophila Paris)	8e-45	46
651) LPE509_02497   ( YP_007569040.1 )	Two component response regulator	NC_020521 (Legionella pneumophila Philadelphia 1)	8e-45	46
652) ompR   ( YP_008062415.1 )	two-component system, OmpR family, copper resistance phosphate regulon response regulator CusR	NC_021350 (Legionella pneumophila Thunder Bay)	8e-45	46
653) GOX0830   ( YP_191260.1 )	two component response regulator	NC_006677 (Gluconobacter oxydans 621H)	2e-44	47
654) cusR   ( YP_004678231.1 )	response regulator in two-component regulatory system with CusS, regulation of copper resistance	NC_015717 (Hyphomicrobium sp. MC1)	2e-44	46
655) cusR   ( YP_006507933.1 )	DNA-binding response regulator in two-component regulatory system with CusS	NC_018140 (Legionella pneumophila HL06041035)	2e-44	45
656) lpl0752   ( YP_126114.1 )	hypothetical protein	NC_006369 (Legionella pneumophila Lens)	2e-44	45
657) lpg0715   ( YP_094751.1 )	two component response regulator	NC_002942 (Legionella pneumophila Philadelphia 1)	2e-44	45
658) Maqu_3740   ( YP_960996.1 )	two component transcriptional regulator	NC_008740 (Marinobacter aquaeolei VT8)	2e-44	43
659) cusR   ( YP_005431521.1 )	DNA-binding response regulator in two-component transcriptional regulatory system, regulation of copper resistance	NC_017067 (Marinobacter hydrocarbonoclasticus ATCC 49840)	2e-44	43
660) Hden_3204   ( YP_003757320.1 )	winged helix family two component transcriptional regulator	NC_014313 (Hyphomicrobium denitrificans ATCC 51888)	3e-44	45
661) cusR   ( YP_008238296.1 )	Copper-sensing two-component system response regulator CusR	NC_021745 (Ralstonia solanacearum FQY_4)	3e-44	61
662) copR   ( NP_522216.1 )	two component response regulator transcription regulator protein	NC_003296 (Ralstonia solanacearum GMI1000)	4e-44	61
663) JCM7686_1818   ( YP_008404686.1 )	two-component response regulator	NC_022041 (Paracoccus aminophilus JCM 7686)	4e-44	46
664) TOL2_C29030   ( YP_006761767.1 )	two component system response regulator, OmpR family, related to CopR	NC_018645 (Desulfobacula toluolica Tol2)	4e-44	45
665) PSPPH_3294   ( YP_275453.1 )	DNA-binding heavy metal response regulator	NC_005773 (Pseudomonas syringae 1448A)	6e-44	56
666) PSPTO_3603   ( NP_793382.1 )	DNA-binding heavy metal response regulator	NC_004578 (Pseudomonas syringae DC3000)	6e-44	56
667) Acry_0450   ( YP_001233594.1 )	two component transcriptional regulator	NC_009484 (Acidiphilium cryptum JF-5)	1e-43	47
668) ACMV_05430   ( YP_004282772.1 )	two-component response regulator	NC_015186 (Acidiphilium multivorum AIU301)	1e-43	47
669) APA386B_872   ( YP_008391696.1 )	two-component response regulator	NC_021991 (Acetobacter pasteurianus 386B)	1e-43	44
670) APA01_19640   ( YP_003188467.1 )	two component response regulator	NC_013209 (Acetobacter pasteurianus IFO 3283)	1e-43	44
671) APA03_19640   ( YP_005478536.1 )	two component response regulator	NC_017100 (Acetobacter pasteurianus IFO 3283)	1e-43	44
672) APA12_19640   ( YP_005481700.1 )	two component response regulator	NC_017108 (Acetobacter pasteurianus IFO 3283)	1e-43	44
673) APA32_19640   ( YP_005484390.1 )	two component response regulator	NC_017111 (Acetobacter pasteurianus IFO 3283)	1e-43	44
674) APA07_19640   ( YP_005487674.1 )	two component response regulator	NC_017121 (Acetobacter pasteurianus IFO 3283)	1e-43	44
675) APA22_19640   ( YP_005490482.1 )	two component response regulator	NC_017125 (Acetobacter pasteurianus IFO 3283)	1e-43	44
676) APA26_19640   ( YP_005499584.1 )	two component response regulator	NC_017146 (Acetobacter pasteurianus IFO 3283)	1e-43	44
677) APA42C_19640   ( YP_005502381.1 )	two component response regulator	NC_017150 (Acetobacter pasteurianus IFO 3283)	1e-43	44
678) CLJU_c17310   ( YP_003779896.1 )	transcriptional regulator	NC_014328 (Clostridium ljungdahlii ATCC 49587)	1e-43	44
679) Desru_0481   ( YP_004544053.1 )	response regulator receiver	NC_015589 (Desulfotomaculum ruminis DSM 2154)	1e-43	44
680) Desor_2309   ( YP_004970417.1 )	response regulator with CheY-like receiver domain and winged-helix DNA-binding domain	NC_016584 (Desulfosporosinus orientis DSM 765)	8e-44	47
681) Rleg_0767   ( YP_002974606.1 )	transcriptional regulator	NC_012850 (Rhizobium leguminosarum WSM1325)	8e-44	45
682) Dtox_3055   ( YP_003192430.1 )	two component transcriptional regulator, winged helix family	NC_013216 (Desulfotomaculum acetoxidans DSM 771)	9e-44	45
683) RL1157   ( YP_766764.1 )	two-component response regulator transcriptional regulatory protein	NC_008380 (Rhizobium leguminosarum 3841)	9e-44	45
684) Cseg_1013   ( YP_003592136.1 )	winged helix family two component transcriptional regulator	NC_014100 (Caulobacter segnis ATCC 21756)	9e-44	44
685) ABLL_0579   ( YP_005552771.1 )	two-component response regulator	NC_017192 (Arcobacter sp. L)	1e-43	45
686) cusR   ( YP_006560008.1 )	transcriptional regulatory protein CusR	NC_018268 (Marinobacter sp. BSs20148)	1e-43	43
687) amb2895   ( YP_422258.1 )	response regulator	NC_007626 (Magnetospirillum magneticum AMB-1)	2e-43	48
688) ragA   ( YP_931961.1 )	two-component response regulator	NC_008702 (Azoarcus sp. BH72)	2e-43	47
689) DGI_2301   ( YP_008591225.1 )	putative two component transcriptional regulator, winged helix family	NC_022444 (Desulfovibrio gigas ATCC 19364)	2e-43	47
690) B932_1350   ( YP_006983863.1 )	two component response regulator	NC_019396 (Gluconobacter oxydans H24)	2e-43	47
691) copR2   ( YP_006397401.1 )	transcriptional activator protein CopR	NC_018000 (Sinorhizobium fredii USDA 257)	2e-43	47
692) Mmwyl1_0419   ( YP_001339292.1 )	two component transcriptional regulator	NC_009654 (Marinomonas sp. MWYL1)	2e-43	46
693) Sbal175_3958   ( YP_006022486.1 )	winged helix family two component transcriptional regulator	NC_017571 (Shewanella baltica BA175)	2e-43	46
694) Sbal117_0396   ( YP_006035687.1 )	winged helix family two component transcriptional regulator	NC_017579 (Shewanella baltica OS117)	2e-43	46
695) Sbal_0293   ( YP_001048695.1 )	two component transcriptional regulator	NC_009052 (Shewanella baltica OS155)	2e-43	46
696) Shew185_0286   ( YP_001364520.1 )	two component transcriptional regulator	NC_009665 (Shewanella baltica OS185)	2e-43	46
697) Sbal223_0298   ( YP_002356257.1 )	winged helix family two component transcriptional regulator	NC_011663 (Shewanella baltica OS223)	2e-43	46
698) A7H1H_0437   ( YP_008330393.1 )	two-component system response regulator	NC_021878 (Arcobacter butzleri 7h1h)	2e-43	45
699) ABED_0409   ( YP_005537936.1 )	two-component response regulator	NC_017187 (Arcobacter butzleri ED-1)	2e-43	45
700) Abu_0434   ( YP_001489378.1 )	two-component response regulator	NC_009850 (Arcobacter butzleri RM4018)	2e-43	45
701) RHE_CH01043   ( YP_468579.1 )	two-component response regulator protein	NC_007761 (Rhizobium etli CFN 42)	2e-43	45
702) Rleg2_0704   ( YP_002280226.1 )	transcriptional regulator	NC_011369 (Rhizobium leguminosarum WSM2304)	2e-43	45
703) DNO_0901   ( YP_001209793.1 )	two-component copper resistance response regulator	NC_009446 (Dichelobacter nodosus VCS1703A)	2e-43	46
704) copR1   ( YP_006397340.1 )	transcriptional activator protein CopR	NC_018000 (Sinorhizobium fredii USDA 257)	3e-43	49
705) HRM2_18670   ( YP_002603133.1 )	two component transcriptional regulator (Winged helix family protein)	NC_012108 (Desulfobacterium autotrophicum HRM2)	3e-43	48
706) AciX9_0521   ( YP_004216373.1 )	transcriptional regulator	NC_015064 (Granulicella tundricola MP5ACTX9)	3e-43	48
707) Mesci_0888   ( YP_004140103.1 )	response regulator receiver	NC_014923 (Mesorhizobium ciceri WSM1271)	3e-43	46
708) Sbal195_0294   ( YP_001552736.1 )	two component transcriptional regulator	NC_009997 (Shewanella baltica OS195)	3e-43	46
709) Sbal678_0301   ( YP_005271554.1 )	two component transcriptional regulator, winged helix family	NC_016901 (Shewanella baltica OS678)	3e-43	46
710) Desgi_0571   ( YP_007943809.1 )	response regulator with CheY-like receiver domain and winged-helix DNA-binding domain	NC_021184 (Desulfotomaculum gibsoniae DSM 7213)	4e-43	47
711) mlr4457   ( NP_105325.1 )	two-component response regulator	NC_002678 (Mesorhizobium loti MAFF303099)	4e-43	46
712) GbCGDNIH1_0146   ( YP_743967.1 )	two-component response regulator	NC_008343 (Granulibacter bethesdensis CGDNIH1)	4e-43	45
713) Mesop_0918   ( YP_004609502.1 )	winged helix family two component transcriptional regulator	NC_015675 (Mesorhizobium opportunistum WSM2075)	4e-43	45
714) Hneap_0785   ( YP_003262681.1 )	transcriptional regulator	NC_013422 (Halothiobacillus neapolitanus c2)	5e-43	46
715) REMIM1_CH01074   ( YP_008363846.1 )	response regulator protein	NC_021905 (Rhizobium etli Mim1)	5e-43	45
716) Tthe_1981   ( YP_003852548.1 )	transcriptional regulator	NC_014410 (Thermoanaerobacterium thermosaccharolyticum DSM 571)	5e-43	44
717) PCC7424_4284   ( YP_002379521.1 )	winged helix family two component transcriptional regulator	NC_011729 (Cyanothece sp. PCC 7424)	6e-43	45
718) Cyan7822_4949   ( YP_003890115.1 )	winged helix family two component transcriptional regulator	NC_014501 (Cyanothece sp. PCC 7822)	7e-43	48
719) Pcar_3081   ( YP_006718877.1 )	winged-helix transcriptional response regulator	NC_007498 (Pelobacter carbinolicus DSM 2380)	7e-43	44
720) Clopa_1269   ( YP_007939934.1 )	response regulator with CheY-like receiver domain and winged-helix DNA-binding domain	NC_021182 (Clostridium pasteurianum BC1)	7e-43	42
721) czrR-1   ( YP_005940636.1 )	DNA-binding response regulator CzrR	NC_017532 (Pseudomonas stutzeri DSM 4166)	1e-42	49
722) COB47_0270   ( YP_003839603.1 )	winged helix family two component transcriptional regulator	NC_014392 (Caldicellulosiruptor obsidiansis OB47)	1e-42	47
723) UWK_01171   ( YP_007467392.1 )	CheY-like receiver and winged-helix DNA-binding domain-containing response regulator	NC_020304 (Desulfocapsa sulfexigens DSM 10523)	1e-42	43
724) HMPREF0409_02293   ( YP_008019777.1 )	hypothetical protein	NC_021281 (Fusobacterium sp. 4_8)	1e-42	43
725) CLS_13420   ( YP_007848980.1 )	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	NC_021047 (Clostridium saccharolyticum K10)	2e-42	47
726) czcR   ( YP_006397746.1 )	transcriptional activator protein CzcR	NC_018000 (Sinorhizobium fredii USDA 257)	2e-42	46
727) ykoG   ( YP_003865716.1 )	two-component response regulator	NC_014479 (Bacillus subtilis W23)	2e-42	44
728) Plav_0944   ( YP_001412224.1 )	two component transcriptional regulator	NC_009719 (Parvibaculum lavamentivorans DS-1)	3e-42	45
729) I653_06790   ( YP_007662122.1 )	sensory transduction protein YkoG	NC_020832 (subtilis subtilis BAB-1)	3e-42	45
730) Mesau_00870   ( YP_007302730.1 )	response regulator with CheY-like receiver domain and winged-helix DNA-binding domain	NC_019973 (Mesorhizobium australicum WSM2073)	3e-42	44
731) Gmet_1026   ( YP_006719993.1 )	winged-helix transcriptional response regulator	NC_007517 (Geobacter metallireducens GS-15)	3e-42	41
732) cusR   ( YP_003797222.1 )	transcriptional regulatory protein CusR	NC_014355 (Candidatus Nitrospira defluvii )	4e-42	49
733) ykoG   ( YP_004876926.1 )	response regulator YkoG	NC_016047 (Bacillus subtilis TU-B-10)	4e-42	45
734) Acid345_1658   ( YP_590733.1 )	two component transcriptional regulator	NC_008009 (Candidatus Koribacter versatilis Ellin345)	4e-42	45
735) BATR1942_04345   ( YP_003972754.1 )	two-component response regulator YkoH	NC_014639 (Bacillus atrophaeus 1942)	4e-42	44
736) FAES_2786   ( YP_007321388.1 )	two component transcriptional regulator, winged helix family	NC_020054 (Fibrella aestuarina BUZ 2)	4e-42	43
737) Emtol_3658   ( YP_006874811.1 )	two component transcriptional regulator, winged helix family	NC_018748 (Emticicia oligotrophica DSM 17448)	4e-42	42
738) Apar_1044   ( YP_003180063.1 )	winged helix family two component transcriptional regulator	NC_013203 (Atopobium parvulum DSM 20469)	5e-42	47
739) Franean1_3859   ( YP_001508157.1 )	two component transcriptional regulator	NC_009921 (Frankia sp. EAN1.pec)	6e-42	48
740) ykoG3   ( YP_005959840.1 )	uncharacterized transcriptional regulatory protein ykoG	NC_017542 (Paenibacillus polymyxa M1)	6e-42	41
741) PPSC2_c2438   ( YP_003946651.1 )	alkaline phosphatase synthesis transcriptional regulatory protein phop	NC_014622 (Paenibacillus polymyxa SC2)	6e-42	41
742) Athe_0280   ( YP_002572201.1 )	winged helix family two component transcriptional regulator	NC_012034 (Caldicellulosiruptor bescii DSM 6725)	7e-42	47
743) CKR_1885   ( YP_002472350.1 )	hypothetical protein	NC_011837 (Clostridium kluyveri NBRC 12016)	7e-42	44
744) Calkr_0253   ( YP_004025431.1 )	two component transcriptional regulator, winged helix family	NC_014721 (Caldicellulosiruptor kristjanssonii 177R1B)	1e-41	45
745) Calla_2096   ( YP_004799636.1 )	winged helix family two component transcriptional regulator	NC_015949 (Caldicellulosiruptor lactoaceticus 6A)	1e-41	45
746) Thimo_3558   ( YP_007245845.1 )	response regulator with CheY-like receiver domain and winged-helix DNA-binding domain	NC_019940 (Thioflavicoccus mobilis 8321)	1e-41	45
747) Slin_4793   ( YP_003389570.1 )	transcriptional regulator	NC_013730 (Spirosoma linguale DSM 74)	1e-41	44
748) TherJR_2684   ( YP_003641420.1 )	two component transcriptional regulator, winged helix family	NC_014152 (Thermincola potens JR)	1e-41	44
749) Thewi_1110   ( YP_004819820.1 )	winged helix family two component transcriptional regulator	NC_015958 (Thermoanaerobacter wiegelii Rt8.B1)	1e-41	44
750) PB2503_00485   ( YP_003856006.1 )	two-component response regulator	NC_014414 (Parvularcula bermudensis HTCC2503)	1e-41	43
751) Desor_4069   ( YP_004972026.1 )	response regulator with CheY-like receiver domain and winged-helix DNA-binding domain	NC_016584 (Desulfosporosinus orientis DSM 765)	8e-42	50
752) Shewana3_0282   ( YP_867931.1 )	two component transcriptional regulator	NC_008577 (Shewanella sp. ANA-3)	8e-42	45
753) Shewmr4_0281   ( YP_732418.1 )	two component transcriptional regulator	NC_008321 (Shewanella sp. MR-4)	8e-42	45
754) Shewmr7_3740   ( YP_739777.1 )	two component transcriptional regulator	NC_008322 (Shewanella sp. MR-7)	8e-42	45
755) CKL_2146   ( YP_001395529.1 )	transcriptional regulator	NC_009706 (Clostridium kluyveri DSM 555)	8e-42	44
756) MY9_1454   ( YP_006231247.1 )	two-component response regulator YkoH	NC_017743 (Bacillus sp. JS)	9e-42	44
757) BALH_2874   ( YP_895652.1 )	two-component response regulator	NC_008600 (Bacillus thuringiensis Al Hakam)	9e-42	43
758) Tsac_1621   ( YP_006392226.1 )	winged helix family two component transcriptional regulator	NC_017992 (Thermoanaerobacterium saccharolyticum JW/SL-YS485)	2e-41	47
759) HCH_00579   ( YP_431907.1 )	response regulator	NC_007645 (Hahella chejuensis KCTC 2396)	2e-41	46
760) ROI_00370   ( YP_007830440.1 )	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	NC_021040 (Roseburia intestinalis M50/1)	2e-41	46
761) Rru_A2913   ( YP_427997.1 )	two component transcriptional regulator	NC_007643 (Rhodospirillum rubrum ATCC 11170)	2e-41	45
762) F11_14935   ( YP_006049246.1 )	two component transcriptional regulator	NC_017584 (Rhodospirillum rubrum F11)	2e-41	45
763) SO_4428   ( NP_719949.1 )	two component signal transduction system response regulator OmpR family	NC_004347 (Shewanella oneidensis MR-1)	2e-41	45
764) Sput200_0256   ( YP_006008210.1 )	winged helix family two component transcriptional regulator	NC_017566 (Shewanella putrefaciens 200)	2e-41	45
765) ykoG   ( NP_389208.1 )	transcriptional regulatory protein YkoG	NC_000964 (Bacillus subtilis 168)	2e-41	44
766) ykoG   ( YP_007533272.1 )	two-component response regulator YkoH	NC_020507 (Bacillus subtilis 6051-HGW)	2e-41	44
767) ykoG   ( YP_005560631.1 )	hypothetical protein	NC_017196 (Bacillus subtilis BEST195)	2e-41	44
768) A7A1_1469   ( YP_007209975.1 )	sensory transduction protein YkoG	NC_019896 (Bacillus subtilis BSP1)	2e-41	44
769) ykoG   ( YP_006629505.1 )	two-component response regulator	NC_018520 (Bacillus subtilis QB928)	2e-41	44
770) CL2_11700   ( YP_007789148.1 )	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	NC_021016 (butyrate-producing bacterium SSC/2)	2e-41	44
771) DAMO_2877   ( YP_003207749.1 )	two-component transcriptional regulator	NC_013260 (Candidatus Methylomirabilis oxyfera )	3e-41	46
772) Sputcn32_0397   ( YP_001181928.1 )	two component transcriptional regulator	NC_009438 (Shewanella putrefaciens CN-32)	3e-41	45
773) Sputw3181_0251   ( YP_961656.1 )	two component transcriptional regulator	NC_008750 (Shewanella sp. W3-18-1)	3e-41	45
774) H9401_3078   ( YP_006210132.1 )	two-component response regulator	NC_017729 (Bacillus anthracis H9401)	3e-41	42
775) BCA_3257   ( YP_002750526.1 )	DNA-binding response regulator	NC_012472 (Bacillus cereus 03BB102)	3e-41	42
776) bcf_15715   ( YP_005119778.1 )	DNA-binding response regulator	NC_016779 (Bacillus cereus F837/76)	3e-41	42
777) FAES_0340   ( YP_007318946.1 )	Transcriptional regulatory protein cusR	NC_020054 (Fibrella aestuarina BUZ 2)	3e-41	45
778) A1S_2937   ( YP_001085944.1 )	heavy metal response regulator	NC_009085 (Acinetobacter baumannii ATCC 17978)	4e-41	52
779) Desdi_0560   ( YP_007219489.1 )	response regulator with CheY-like receiver domain and winged-helix DNA-binding domain	NC_019903 (Desulfitobacterium dichloroeliminans LMG P-21439)	5e-41	48
780) Clos_0943   ( YP_001512486.1 )	two component transcriptional regulator	NC_009922 (Alkaliphilus oremlandii OhILAs)	5e-41	45
781) ykoG   ( YP_007426513.1 )	two-component response regulator	NC_020244 (Bacillus subtilis XF-1)	5e-41	45
782) GNIT_2765   ( YP_004872855.1 )	two-component response regulator	NC_016041 (Glaciecola nitratireducens FR1064)	5e-41	44
783) Sph21_1638   ( YP_004316870.1 )	winged helix family two component transcriptional regulator	NC_015277 (Sphingobacterium sp. 21)	5e-41	44
784) BCAH820_3235   ( YP_002452185.1 )	DNA-binding response regulator	NC_011773 (Bacillus cereus AH820)	5e-41	42
785) G432_17260   ( YP_007617766.1 )	two component transcriptional regulator	NC_020561 (Sphingomonas sp. MM-1)	6e-41	48
786) Glov_0998   ( YP_001951241.1 )	winged helix family two component transcriptional regulator	NC_010814 (Geobacter lovleyi SZ)	6e-41	47
787) Kole_0551   ( YP_002940275.1 )	two component transcriptional regulator, winged helix family	NC_012785 (Kosmotoga olearia TBF 19.5.1)	6e-41	47
788) Clole_0019   ( YP_004306979.1 )	transcriptional regulator	NC_015275 (Clostridium lentocellum DSM 5427)	1e-40	45
789) BAA_3276   ( YP_002867425.1 )	DNA-binding response regulator	NC_012659 (Bacillus anthracis A0248)	1e-40	42
790) BA_3229   ( NP_845535.1 )	DNA-binding response regulator	NC_003997 (Bacillus anthracis Ames)	1e-40	42
791) GBAA_3229   ( YP_019868.1 )	DNA-binding response regulator	NC_007530 (Bacillus anthracis Ames Ancestor)	1e-40	42
792) BAMEG_1385   ( YP_002813988.1 )	DNA-binding response regulator	NC_012581 (Bacillus anthracis CDC 684)	1e-40	42
793) BAS2999   ( YP_029256.1 )	DNA-binding response regulator	NC_005945 (Bacillus anthracis Sterne)	1e-40	42
794) HPL003_22815   ( YP_005077510.1 )	alkaline phosphatase synthesis transcriptional regulatory protein phop	NC_016641 (Paenibacillus terrae HPL-003)	1e-40	41
795) Mmar10_0943   ( YP_756174.1 )	two component transcriptional regulator	NC_008347 (Maricaulis maris MCS10)	7e-41	45
796) Calni_0142   ( YP_004050219.1 )	winged helix family two component transcriptional regulator	NC_014758 (Calditerrivibrio nitroreducens DSM 19672)	7e-41	43
797) BACI_c31720   ( YP_003792928.1 )	transcriptional regulator	NC_014335 (Bacillus cereus CI)	7e-41	42
798) Ilyop_2167   ( YP_003968278.1 )	two component transcriptional regulator, winged helix family	NC_014633 (Ilyobacter polytropus DSM 2926)	8e-41	47
799) ykoG   ( YP_005556435.1 )	response regulator YkoG	NC_017195 (Bacillus subtilis RO-NN-1)	8e-41	44
800) Niako_5824   ( YP_005011458.1 )	two component transcriptional regulator, winged helix family	NC_016609 (Niastella koreensis GR20-10)	8e-41	44
801) Oter_1727   ( YP_001818611.1 )	two component transcriptional regulator	NC_010571 (Opitutus terrae PB90-1)	9e-41	45
802) Desaf_1136   ( YP_005051138.1 )	two component transcriptional regulator, winged helix family	NC_016629 (Desulfovibrio africanus Walvis Bay)	1e-40	45
803) IALB_0152   ( YP_005845132.1 )	OmpR family response regulator	NC_017464 (Ignavibacterium album JCM 16511)	1e-40	45
804) Gdia_2157   ( YP_002276530.1 )	winged helix family two component transcriptional regulator	NC_011365 (Gluconacetobacter diazotrophicus PAl 5)	2e-40	46
805) AZC_1137   ( YP_001524053.1 )	response regulator receiver	NC_009937 (Azorhizobium caulinodans ORS 571)	2e-40	44
806) PB2503_08144   ( YP_003854826.1 )	two component response regulatorT	NC_014414 (Parvularcula bermudensis HTCC2503)	2e-40	44
807) Desca_2243   ( YP_004497993.1 )	winged helix family two component transcriptional regulator	NC_015565 (Desulfotomaculum carboxydivorans CO-1-SRB)	2e-40	43
808) swp_3181   ( YP_002312476.1 )	Response regulator receiver:Transcriptional regulatory protein	NC_011566 (Shewanella piezotolerans WP3)	2e-40	43
809) RTO_02800   ( YP_007785567.1 )	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	NC_021015 ([Ruminococcus] torques L2-14)	2e-40	43
810) BCG9842_B2033   ( YP_002446682.1 )	DNA-binding response regulator	NC_011772 (Bacillus cereus G9842)	2e-40	41
811) BTG_03395   ( YP_006602211.1 )	DNA-binding response regulator	NC_018500 (Bacillus thuringiensis HD-771)	2e-40	41
812) BTF1_13445   ( YP_006610792.1 )	DNA-binding response regulator	NC_018508 (Bacillus thuringiensis HD-789)	2e-40	41
813) Mrad2831_3484   ( YP_001756144.1 )	two component transcriptional regulator	NC_010505 (Methylobacterium radiotolerans JCM 2831)	2e-40	41
814) Swit_4798   ( YP_001265273.1 )	two component transcriptional regulator	NC_009511 (Sphingomonas wittichii RW1)	2e-40	49
815) Shal_0132   ( YP_001672367.1 )	two component transcriptional regulator	NC_010334 (Shewanella halifaxensis HAW-EB4)	3e-40	45
816) Slin_2929   ( YP_003387741.1 )	transcriptional regulator	NC_013730 (Spirosoma linguale DSM 74)	3e-40	44
817) cusR   ( YP_004676151.1 )	response regulator in two-component regulatory system with CusS, regulation of copper resistance	NC_015717 (Hyphomicrobium sp. MC1)	3e-40	42
818) BC3200   ( NP_832941.1 )	two-component response regulator	NC_004722 (Bacillus cereus ATCC 14579 )	3e-40	41
819) Arnit_3130   ( YP_003657282.1 )	winged helix family two component transcriptional regulator	NC_014166 (Arcobacter nitrofigilis DSM 7299)	4e-40	47
820) CC_2757   ( NP_421553.1 )	DNA-binding response regulator	NC_002696 (Caulobacter crescentus CB15)	4e-40	44
821) CCNA_02845   ( YP_002518218.1 )	two-component response regulator	NC_011916 (Caulobacter crescentus NA1000)	4e-40	44
822) Lbys_1633   ( YP_003997694.1 )	winged helix family two component transcriptional regulator	NC_014655 (Leadbetterella byssophila DSM 17132)	4e-40	42
823) BCB4264_A3221   ( YP_002367927.1 )	DNA-binding response regulator	NC_011725 (Bacillus cereus B4264)	4e-40	41
824) BTB_c32820   ( YP_006927903.1 )	Two-component response regulator	NC_018877 (Bacillus thuringiensis Bt407)	4e-40	41
825) CT43_CH3148   ( YP_005573110.1 )	two-component response regulator	NC_017208 (Bacillus thuringiensis CT-43)	4e-40	41
826) H175_ch3203   ( YP_007479664.1 )	DNA-binding response regulator	NC_020376 (Bacillus thuringiensis IS5056)	4e-40	41
827) Lebu_1041   ( YP_003163932.1 )	winged helix family two component transcriptional regulator	NC_013192 (Leptotrichia buccalis DSM 1135)	4e-40	41
828) sce3288   ( YP_001613927.1 )	two-component response regulator	NC_010162 (Sorangium cellulosum So ce 56)	5e-40	43
829) Shew_0097   ( YP_001092228.1 )	two component transcriptional regulator	NC_009092 (Shewanella loihica PV-4)	1e-39	45
830) Sfri_0090   ( YP_748791.1 )	two component transcriptional regulator, winged helix family protein	NC_008345 (Shewanella frigidimarina NCIMB 400)	5e-40	43
831) swp_4998   ( YP_002314200.1 )	Response regulator receiver:Transcriptional regulatory protein	NC_011566 (Shewanella piezotolerans WP3)	7e-40	44
832) Caul_3888   ( YP_001685511.1 )	two component transcriptional regulator	NC_010338 (Caulobacter sp. K31)	7e-40	43
833) A11S_1912   ( YP_007643333.1 )	response regulator in two-component regulatory system with PhoQ	NC_020812 (Micavibrio aeruginosavorus EPB)	7e-40	43
834) ragA   ( YP_004304628.1 )	response regulators consisting of a chemotaxis protein CheY domain and a winged-helix DNA-binding domain	NC_015259 (Polymorphum gilvum SL003B-26A1)	7e-40	42
835) Swoo_4783   ( YP_001763127.1 )	two component transcriptional regulator	NC_010506 (Shewanella woodyi ATCC 51908)	8e-40	45
836) GM21_0227   ( YP_003020070.1 )	transcriptional regulator	NC_012918 (Geobacter sp. M21)	9e-40	46
837) DMR_37840   ( YP_002955161.1 )	OmpR family two-component response regulator	NC_012796 (Desulfovibrio magneticus RS-1)	9e-40	44
838) RSPPHO_01922   ( YP_005417518.1 )	Two component transcriptional regulator, winged helix family	NC_017059 (Rhodospirillum photometricum DSM 122)	1e-39	48
839) Cphamn1_0990   ( YP_001959414.1 )	winged helix family two component transcriptional regulator	NC_010831 (Chlorobium phaeobacteroides BS1)	1e-39	45
840) GM18_0272   ( YP_004197037.1 )	winged helix family two component transcriptional regulator	NC_014973 (Geobacter sp. M18)	1e-39	45
841) Spea_4110   ( YP_001503955.1 )	two component transcriptional regulator	NC_009901 (Shewanella pealeana ATCC 700345)	1e-39	45
842) Bresu_0884   ( YP_003817821.1 )	transcriptional regulator	NC_014375 (Brevundimonas subvibrioides ATCC 15264)	1e-39	44
843) colR   ( YP_158896.1 )	DNA-binding response regulator ColR	NC_006513 (Aromatoleum aromaticum EbN1)	1e-39	43
844) Swit_4516   ( YP_001264992.1 )	two component transcriptional regulator	NC_009511 (Sphingomonas wittichii RW1)	1e-39	43
845) GLX_12800   ( YP_004868062.1 )	two component response regulator	NC_016027 (Gluconacetobacter xylinus NBRC 3288)	2e-39	45
846) Tlie_0721   ( YP_004932551.1 )	two component transcriptional regulator, winged helix family	NC_016148 (Thermovirga lienii DSM 17291)	2e-39	44
847) Echvi_2622   ( YP_007224874.1 )	response regulator with CheY-like receiver domain and winged-helix DNA-binding domain	NC_019904 (Echinicola vietnamensis DSM 17526)	2e-39	43
848) pcoR   ( YP_007521519.1 )	Transcriptional regulatory protein pcoR	NC_020504 (Streptomyces davawensis JCM 4913)	2e-39	43
849) MC28_0224   ( YP_006827045.1 )	hypothetical protein	NC_018693 (Bacillus thuringiensis MC28)	2e-39	41
850) cusR   ( YP_002961462.1 )	response regulator in two-component regulatory system with CusS, regulation of copper resistance	NC_012808 (Methylobacterium extorquens AM1)	2e-39	41
851) cusR   ( YP_003065940.1 )	response regulator in two-component regulatory system with CusS, regulation of copper resistance	NC_012988 (Methylobacterium extorquens DM4)	2e-39	41
852) Gbem_0243   ( YP_002137070.1 )	transcriptional regulator	NC_011146 (Geobacter bemidjiensis Bem)	3e-39	46
853) Haur_2799   ( YP_001545565.1 )	two component transcriptional regulator	NC_009972 (Herpetosiphon aurantiacus DSM 785)	3e-39	44
854) Ssed_4392   ( YP_001476122.1 )	two component transcriptional regulator	NC_009831 (Shewanella sediminis HAW-EB3)	3e-39	44
855) FAES_2892   ( YP_007321494.1 )	two component transcriptional regulator, winged helix family	NC_020054 (Fibrella aestuarina BUZ 2)	3e-39	43
856) KQS_05010   ( YP_005357025.1 )	two-component system response regulatory protein	NC_017025 (Flavobacterium indicum GPTSA100-9)	3e-39	43
857) PSE_p0334   ( YP_005086883.1 )	two component heavy metal response transcriptional regulator, winged helix family	NC_016646 (Pseudovibrio sp. FO-BEG1)	3e-39	43
858) BARBAKC583_0435   ( YP_988753.1 )	DNA-binding response regulator	NC_008783 (Bartonella bacilliformis KC583)	3e-39	41
859) Cpin_3739   ( YP_003123402.1 )	winged helix family two component transcriptional regulator	NC_013132 (Chitinophaga pinensis DSM 2588)	3e-39	41
860) MICA_2209   ( YP_004866516.1 )	response regulator	NC_016026 (Micavibrio aeruginosavorus ARL-13)	3e-39	41
861) AvCA_15530   ( YP_007892553.1 )	heavy metal response regulator, two-component	NC_021149 (Azotobacter vinelandii CA)	4e-39	55
862) AvCA6_15530   ( YP_007897602.1 )	heavy metal response regulator, two-component	NC_021150 (Azotobacter vinelandii CA6)	4e-39	55
863) Avin_15530   ( YP_002798743.1 )	heavy metal response regulator, two-component	NC_012560 (Azotobacter vinelandii DJ)	4e-39	55
864) SVI_4239   ( YP_003558988.1 )	DNA-binding response regulator	NC_014012 (Shewanella violacea DSS12)	4e-39	46
865) Ccur_00280   ( YP_003150443.1 )	response regulator with CheY-like receiver domain protein and winged-helix DNA-binding domain protein	NC_013170 (Cryptobacterium curtum DSM 15641)	4e-39	44
866) Bdt_2501   ( YP_007023451.1 )	2-component transcriptional regulator	NC_019567 (Bdellovibrio bacteriovorus Tiberius)	4e-39	43
867) Bind_2236   ( YP_001833343.1 )	two component transcriptional regulator	NC_010581 (Beijerinckia indica ATCC 9039)	4e-39	42
868) Cpar_1213   ( YP_001998818.1 )	winged helix family two component transcriptional regulator	NC_011027 (Chlorobaculum parvum NCIB 8327)	4e-39	42
869) Snas_2104   ( YP_003510891.1 )	winged helix family two component transcriptional regulator	NC_013947 (Stackebrandtia nassauensis DSM 44728)	5e-39	46
870) Avi_9846   ( YP_002546508.1 )	two component response regulator	NC_011986 (Agrobacterium vitis S4)	5e-39	44
871) AZOBR_p350049   ( YP_004986826.1 )	two-component transcriptional regulator involved in heavy-metal (Cu/Zn) homeostasis	NC_016595 (Azospirillum brasilense Sp245)	5e-39	42
872) Hden_0349   ( YP_003754495.1 )	winged helix family two component transcriptional regulator	NC_014313 (Hyphomicrobium denitrificans ATCC 51888)	7e-39	42
873) Mchl_0376   ( YP_002419241.1 )	transcriptional regulator	NC_011757 (Methylobacterium chloromethanicum CM4)	7e-39	41
874) B5T_04181   ( YP_006822784.1 )	response regulator	NC_018691 (Alcanivorax dieselolei B5)	8e-39	41
875) PP1Y_AT16532   ( YP_004534348.1 )	two-component system OmpR family response regulator	NC_015580 (Novosphingobium sp. PP1Y)	1e-38	46
876) cusR   ( YP_006941054.1 )	Transcriptional regulatory protein cusR	NC_019012 (Fibrella aestuarina BUZ 2)	1e-38	45
877) Runsl_0028   ( YP_004653620.1 )	winged helix family two component transcriptional regulator	NC_015703 (Runella slithyformis DSM 19594)	1e-38	45
878) llrE   ( YP_007508098.1 )	DNA-binding response regulator, OmpR family	NC_020450 (Lactococcus lactis IO-1)	1e-38	44
879) PM3016_6374   ( YP_005316155.1 )	protein MprA	NC_016935 (Paenibacillus mucilaginosus 3016)	1e-38	42
880) B2K_32230   ( YP_006193086.1 )	transcriptional regulator	NC_017672 (Paenibacillus mucilaginosus K02)	1e-38	42
881) mprA   ( YP_004645142.1 )	protein MprA	NC_015690 (Paenibacillus mucilaginosus KNP414)	1e-38	42
882) Riv7116_3368   ( YP_007056374.1 )	response regulator with CheY-like receiver domain and winged-helix DNA-binding domain	NC_019678 (Rivularia sp. PCC 7116)	1e-38	42
883) Msil_0189   ( YP_002360532.1 )	winged helix family two component transcriptional regulator	NC_011666 (Methylocella silvestris BL2)	1e-38	41
884) Thena_1465   ( YP_004438208.1 )	two component transcriptional regulator, winged helix family	NC_015499 (Thermodesulfobium narugense DSM 14796)	8e-39	43
885) Bpet1596   ( YP_001630204.1 )	two-component transcriptional regulator	NC_010170 (Bordetella petrii DSM 12804)	8e-39	41
886) cur_0545   ( YP_001799939.1 )	two-component system response regulator MprA	NC_010545 (Corynebacterium urealyticum DSM 7109)	8e-39	41
887) HYPDE_23408   ( YP_007912867.1 )	winged helix family two component transcriptional regulator	NC_021172 (Hyphomicrobium denitrificans 1NES1)	8e-39	41
888) Mext_0329   ( YP_001637824.1 )	response regulator receiver	NC_010172 (Methylobacterium extorquens PA1)	8e-39	41
889) Pmob_0851   ( YP_001567898.1 )	two component transcriptional regulator	NC_010003 (Petrotoga mobilis SJ95)	2e-38	45
890) Psefu_1127   ( YP_004473198.1 )	two component transcriptional regulator, winged helix family	NC_015556 (Pseudomonas fulva 12-X)	2e-38	44
891) ompR   ( YP_007320826.1 )	Transcriptional regulatory protein cusR	NC_020054 (Fibrella aestuarina BUZ 2)	2e-38	42
892) CSSP291_21073   ( YP_007442910.1 )	Transcriptional regulatory protein pcoR	NC_020261 (Cronobacter sakazakii Sp291)	3e-38	55
893) Varpa_4948   ( YP_004157219.1 )	winged helix family two component transcriptional regulator	NC_014931 (Variovorax paradoxus EPS)	3e-38	42
894) Dhaf_1005   ( YP_002457501.1 )	transcriptional regulator	NC_011830 (Desulfitobacterium hafniense DCB-2)	3e-38	41
895) DSY4317   ( YP_520550.1 )	hypothetical protein	NC_007907 (Desulfitobacterium hafniense Y51)	3e-38	41
896) Oscil6304_2879   ( YP_007086401.1 )	response regulator with CheY-like receiver domain and winged-helix DNA-binding domain	NC_019693 (Oscillatoria acuminata PCC 6304)	4e-38	44
897) CLK_2843   ( YP_001788740.1 )	alkaline phosphatase synthesis transcriptional regulatory protein PhoP	NC_010520 (Clostridium botulinum Loch Maree)	5e-38	43
898) Fjoh_3400   ( YP_001195733.1 )	two component transcriptional regulator	NC_009441 (Flavobacterium johnsoniae UW101)	5e-38	43
899) GAU_2879   ( YP_002762391.1 )	OmpR family two-component response regulator	NC_012489 (Gemmatimonas aurantiaca T-27)	5e-38	43
900) Halhy_6214   ( YP_004450908.1 )	winged helix family two component transcriptional regulator	NC_015510 (Haliscomenobacter hydrossis DSM 1100)	6e-38	45
901) BSn5_18655   ( YP_004207364.1 )	two-component response regulator YkoH	NC_014976 (Bacillus subtilis BSn5)	6e-38	44
902) ykoG   ( YP_007985000.1 )	two-component response regulator [YkoH]	NC_021219 (Candidatus Saccharimonas aalborgensis )	6e-38	43
903) Niako_7236   ( YP_005012855.1 )	two component transcriptional regulator, winged helix family	NC_016609 (Niastella koreensis GR20-10)	6e-38	43
904) Psest_3465   ( YP_007241584.1 )	response regulator with CheY-like receiver domain and winged-helix DNA-binding domain	NC_019936 (Pseudomonas stutzeri RCH2)	6e-38	43
905) Sca_1060   ( YP_002634153.1 )	putative response regulator protein	NC_012121 (Staphylococcus carnosus TM300)	6e-38	43
906) colR   ( YP_007892778.1 )	response regulator, transcriptional regulatory protein (two-component), ColR	NC_021149 (Azotobacter vinelandii CA)	6e-38	42
907) colR   ( YP_007897827.1 )	response regulator, transcriptional regulatory protein (two-component), ColR	NC_021150 (Azotobacter vinelandii CA6)	6e-38	42
908) colR   ( YP_002798968.1 )	response regulator, transcriptional regulatory protein (two-component), ColR	NC_012560 (Azotobacter vinelandii DJ)	6e-38	42
909) AARI_02110   ( YP_003915418.1 )	two-component system response regulator	NC_014550 (Arthrobacter arilaitensis Re117)	1e-37	45
910) mprA   ( YP_007416365.1 )	two-component system response regulator MprA	NC_020230 (Corynebacterium urealyticum DSM 7111)	1e-37	42
911) CPF_1056   ( YP_695502.1 )	DNA-binding response regulator	NC_008261 (Clostridium perfringens ATCC 13124)	1e-37	41
912) Desde_0924   ( YP_006429154.1 )	response regulator with CheY-like receiver domain and winged-helix DNA-binding domain	NC_018017 (Desulfitobacterium dehalogenans ATCC 51507)	1e-37	41
913) Cpin_1247   ( YP_003120946.1 )	winged helix family two component transcriptional regulator	NC_013132 (Chitinophaga pinensis DSM 2588)	8e-38	42
914) Thexy_2336   ( YP_004472008.1 )	two component transcriptional regulator, winged helix family	NC_015555 (Thermoanaerobacterium xylanolyticum LX-11)	8e-38	41
915) Lepto7376_1023   ( YP_007070228.1 )	winged helix family two component transcriptional regulator	NC_019683 (Leptolyngbya sp. PCC 7376)	9e-38	43
916) Tsac_0443   ( YP_006391072.1 )	winged helix family two component transcriptional regulator	NC_017992 (Thermoanaerobacterium saccharolyticum JW/SL-YS485)	9e-38	41
917) THEYE_A0752   ( YP_002248594.1 )	DNA-binding response regulator	NC_011296 (Thermodesulfovibrio yellowstonii DSM 11347)	1e-37	46
918) PP1Y_Mpl1894   ( YP_004538122.1 )	two-component system OmpR family response regulator	NC_015583 (Novosphingobium sp. PP1Y)	2e-37	49
919) Acid_5477   ( YP_826709.1 )	two component transcriptional regulator	NC_008536 (Candidatus Solibacter usitatus Ellin6076)	2e-37	47
920) OBV_07280   ( YP_004880432.1 )	OmpR family two-component response regulator	NC_016048 (Oscillibacter valericigenes Sjm18-20)	2e-37	47
921) Acid_2164   ( YP_823439.1 )	two component heavy metal response transcriptional regulator	NC_008536 (Candidatus Solibacter usitatus Ellin6076)	2e-37	45
922) MLP_28070   ( YP_004573224.1 )	two-component system response regulator	NC_015635 (Microlunatus phosphovorus NM-1)	2e-37	45
923) Aaci_2264   ( YP_003185662.1 )	winged helix family two component transcriptional regulator	NC_013205 (Alicyclobacillus acidocaldarius DSM 446)	2e-37	44
924) HTH_1434   ( YP_003433086.1 )	two-component transcriptional regulator	NC_013799 (Hydrogenobacter thermophilus TK-6)	2e-37	43
925) Hydth_1423   ( YP_005512101.1 )	winged helix family two component transcriptional regulator	NC_017161 (Hydrogenobacter thermophilus TK-6)	2e-37	43
926) tcsR5   ( YP_251323.1 )	two-component system response regulator TcsR5	NC_007164 (Corynebacterium jeikeium K411)	2e-37	42
927) Gbro_4258   ( YP_003275297.1 )	response regulator receiver	NC_013441 (Gordonia bronchialis DSM 43247)	2e-37	42
928) ompR   ( YP_001939258.1 )	DNA-binding response regulator, OmpR family (REC-wHTH domains)	NC_010794 (Methylacidiphilum infernorum V4)	2e-37	42
929) A458_17220   ( YP_006459092.1 )	response regulator, transcriptional regulatory protein (two-component), ColR	NC_018028 (Pseudomonas stutzeri CCUG 29243)	2e-37	42
930) Cal7507_1776   ( YP_007065066.1 )	winged helix family two component transcriptional regulator	NC_019682 (Calothrix sp. PCC 7507)	2e-37	41
931) Nos7107_2779   ( YP_007050527.1 )	winged helix family two component transcriptional regulator	NC_019676 (Nostoc sp. PCC 7107)	2e-37	41
932) GDI_1456   ( YP_001601712.1 )	two-component response regulator	NC_010125 (Gluconacetobacter diazotrophicus PAl 5)	3e-37	45
933) PB2503_00355   ( YP_003855980.1 )	DNA-binding response regulator	NC_014414 (Parvularcula bermudensis HTCC2503)	3e-37	44
934) BN112_3035   ( YP_006969083.1 )	transcriptional regulator	NC_019382 (Bordetella bronchiseptica 253)	3e-37	43
935) BN117_0373   ( YP_006894441.1 )	transcriptional regulator	NC_018828 (Bordetella parapertussis Bpp5)	3e-37	43
936) Runsl_2442   ( YP_004655979.1 )	winged helix family two component transcriptional regulator	NC_015703 (Runella slithyformis DSM 19594)	3e-37	43
937) KSE_05880   ( YP_004902387.1 )	putative two-component system response regulator	NC_016109 (Kitasatospora setae KM-6054)	3e-37	42
938) gcrR   ( YP_006250529.1 )	response regulator GcrR for glucan-binding protein C	NC_017768 (Streptococcus mutans LJ23)	3e-37	42
939) gcrR   ( YP_003484145.1 )	response regulator GcrR for glucan-binding protein C	NC_013928 (Streptococcus mutans NN2025)	3e-37	42
940) gcrR   ( NP_722229.1 )	response regulator GcrR for glucan-binding protein C	NC_004350 (Streptococcus mutans UA159)	3e-37	42
941) AZOLI_p20676   ( YP_004974927.1 )	Two-component response regulator	NC_016586 (Azospirillum lipoferum 4B)	3e-37	41
942) ragA   ( YP_007022822.1 )	two component response regulator	NC_019567 (Bdellovibrio bacteriovorus Tiberius)	3e-37	41
943) Saro_1599   ( YP_496873.1 )	two component transcriptional regulator	NC_007794 (Novosphingobium aromaticivorans DSM 12444)	4e-37	45
944) BN115_0364   ( YP_006898624.1 )	transcriptional regulator	NC_018829 (Bordetella bronchiseptica MO149)	4e-37	43
945) HNE_1312   ( YP_760030.1 )	DNA-binding response regulator	NC_008358 (Hyphomonas neptunium ATCC 15444)	4e-37	43
946) Hden_1134   ( YP_003755269.1 )	winged helix family two component transcriptional regulator	NC_014313 (Hyphomicrobium denitrificans ATCC 51888)	4e-37	42
947) Sden_0109   ( YP_561129.1 )	response regulator receiver	NC_007954 (Shewanella denitrificans OS217)	4e-37	42
948) Thewi_2650   ( YP_004821258.1 )	winged helix family two component transcriptional regulator	NC_015958 (Thermoanaerobacter wiegelii Rt8.B1)	4e-37	42
949) Thethe_02717   ( YP_007299976.1 )	response regulator with CheY-like receiver domain and winged-helix DNA-binding domain	NC_019970 (Thermoanaerobacterium thermosaccharolyticum M0795)	4e-37	42
950) Mrub_1103   ( YP_003506887.1 )	winged helix family two component transcriptional regulator	NC_013946 (Meiothermus ruber DSM 1279)	4e-37	41
951) K649_05160   ( YP_007879831.1 )	winged helix family two component transcriptional regulator	NC_021081 (Meiothermus ruber DSM 1279)	4e-37	41
952) AciPR4_2224   ( YP_004183020.1 )	winged helix family two component transcriptional regulator	NC_014963 (Terriglobus saanensis SP1PR4)	4e-37	41
953) Desdi_0824   ( YP_007219745.1 )	response regulator with CheY-like receiver domain and winged-helix DNA-binding domain	NC_019903 (Desulfitobacterium dichloroeliminans LMG P-21439)	5e-37	42
954) FAES_3332   ( YP_007321933.1 )	two component transcriptional regulator, winged helix family	NC_020054 (Fibrella aestuarina BUZ 2)	5e-37	42
955) Sfum_2007   ( YP_846125.1 )	two component transcriptional regulator	NC_008554 (Syntrophobacter fumaroxidans MPOB)	5e-37	48
956) OB0594   ( NP_691515.1 )	two-component response regulator	NC_004193 (Oceanobacillus iheyensis HTE831)	5e-37	44
957) Tthe_2686   ( YP_003853219.1 )	transcriptional regulator	NC_014410 (Thermoanaerobacterium thermosaccharolyticum DSM 571)	5e-37	42
958) GPOL_c44420   ( YP_005284811.1 )	putative two-component system regulator	NC_016906 (Gordonia polyisoprenivorans VH2)	5e-37	41
959) Clocel_1314   ( YP_003842832.1 )	two component transcriptional regulator, winged helix family	NC_014393 (Clostridium cellulovorans 743B)	6e-37	43
960) CSE_01430   ( YP_005472372.1 )	OmpR family two-component system response regulator	NC_017096 (Caldisericum exile AZM16c01)	6e-37	42
961) B841_04050   ( YP_008370780.1 )	two-component system response regulator MprA	NC_021915 (Corynebacterium maris DSM 45190)	6e-37	41
962) Npun_R5316   ( YP_001868580.1 )	two component transcriptional regulator	NC_010628 (Nostoc punctiforme PCC 73102)	6e-37	41
963) Geoth_1513   ( YP_004587577.1 )	winged helix family two component transcriptional regulator	NC_015660 (Geobacillus thermoglucosidasius C56-YS93)	7e-37	44
964) BPP0376   ( NP_882730.1 )	transcriptional regulatory protein	NC_002928 (Bordetella parapertussis 12822)	7e-37	43
965) GY4MC1_1403   ( YP_003988815.1 )	transcriptional regulator	NC_014650 (Geobacillus sp. Y4.1MC1)	8e-37	44
966) Ava_3453   ( YP_323955.1 )	two component transcriptional regulator	NC_007413 (Anabaena variabilis ATCC 29413)	8e-37	43
967) Theco_1731   ( YP_007212861.1 )	response regulator with CheY-like receiver domain and winged-helix DNA-binding domain	NC_019897 (Thermobacillus composti KWC4)	8e-37	43
968) Halhy_0426   ( YP_004445210.1 )	winged helix family two component transcriptional regulator	NC_015510 (Haliscomenobacter hydrossis DSM 1100)	8e-37	42
969) HYPDE_31988   ( YP_007914571.1 )	winged helix family two component transcriptional regulator	NC_021172 (Hyphomicrobium denitrificans 1NES1)	8e-37	42
970) Dfer_2743   ( YP_003087123.1 )	winged helix family two component transcriptional regulator	NC_013037 (Dyadobacter fermentans DSM 18053)	9e-37	42
971) Emtol_0288   ( YP_006870449.1 )	two component transcriptional regulator, winged helix family	NC_018742 (Emticicia oligotrophica DSM 17448)	9e-37	41
972) Caur_2506   ( YP_001636101.1 )	response regulator receiver	NC_010175 (Chloroflexus aurantiacus J-10-fl)	1e-36	45
973) Chy400_2703   ( YP_002570418.1 )	winged helix family two component transcriptional regulator	NC_012032 (Chloroflexus sp. Y-400-fl)	1e-36	45
974) cztR   ( YP_003796011.1 )	heavy metal response regulator	NC_014355 (Candidatus Nitrospira defluvii )	1e-36	44
975) Clopa_1309   ( YP_007939972.1 )	response regulator with CheY-like receiver domain and winged-helix DNA-binding domain	NC_021182 (Clostridium pasteurianum BC1)	1e-36	44
976) Olsu_1502   ( YP_003801481.1 )	two component transcriptional regulator, winged helix family	NC_014363 (Olsenella uli DSM 7084)	1e-36	44
977) AMBLS11_14415   ( YP_006825907.1 )	response regulator consisting of a CheY-like receiver domain-containing protein and a winged-helix DNA-binding domain-containing protein	NC_018692 (Alteromonas macleodii Black Sea 11)	1e-36	43
978) BB0379   ( NP_886928.1 )	transcriptional regulatory protein	NC_002927 (Bordetella bronchiseptica RB50)	1e-36	43
979) Snas_4900   ( YP_003513634.1 )	winged helix family two component transcriptional regulator	NC_013947 (Stackebrandtia nassauensis DSM 44728)	1e-36	43
980) vicR   ( YP_005519682.1 )	winged helix family two component transcriptional regulator	NC_017167 (Alicyclobacillus acidocaldarius Tc-4-1)	1e-36	42
981) LBUCD034_1866   ( YP_006726439.1 )	DNA-binding response regulator	NC_018610 (Lactobacillus buchneri CD034)	1e-36	41
982) FsymDg_3491   ( YP_004584701.1 )	winged helix family two component transcriptional regulator	NC_015656 (Frankia sp. 4085684)	2e-36	46
983) GAU_3842   ( YP_002763354.1 )	OmpR family two-component response regulator	NC_012489 (Gemmatimonas aurantiaca T-27)	2e-36	45
984) czcR   ( YP_005263065.1 )	transcriptional regulator	NC_016887 (Nocardia cyriacigeorgica GUH-2)	2e-36	45
985) Cagg_1351   ( YP_002462694.1 )	winged helix family two component transcriptional regulator	NC_011831 (Chloroflexus aggregans DSM 9485)	2e-36	44
986) CCALI_01167   ( YP_008089110.1 )	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	NC_021487 (Chthonomonas calidirosea T49)	2e-36	44
987) Tmar_1587   ( YP_004102423.1 )	transcriptional regulator	NC_014831 (Thermaerobacter marianensis DSM 12885)	2e-36	44
988) Xaut_3517   ( YP_001418403.1 )	two component transcriptional regulator	NC_009720 (Xanthobacter autotrophicus Py2)	2e-36	43
989) Aaci_2922   ( YP_003186314.1 )	winged helix family two component transcriptional regulator	NC_013205 (Alicyclobacillus acidocaldarius DSM 446)	2e-36	42
990) colR   ( YP_008105035.1 )	two-component response regulator ColR	NC_021499 (Pseudomonas resinovorans NBRC 106553)	2e-36	42
991) Tmath_2222   ( YP_003677899.1 )	winged helix family two component transcriptional regulator	NC_014209 (Thermoanaerobacter mathranii A3)	2e-36	42
992) Anacy_5445   ( YP_007159670.1 )	two component transcriptional regulator, winged helix family	NC_019771 (Anabaena cylindrica PCC 7122)	2e-36	41
993) cusR   ( YP_005950512.1 )	transcriptional regulatory protein CusR	NC_017538 (Oligotropha carboxidovorans OM4)	2e-36	41
994) cusR   ( YP_004632448.1 )	transcriptional regulator CusR	NC_015684 (Oligotropha carboxidovorans OM5)	2e-36	41
995) OCAR_6571   ( YP_002289548.1 )	transcriptional activator protein CopR	NC_011386 (Oligotropha carboxidovorans OM5; ATCC 49405)	2e-36	41
996) KKY_788   ( YP_004898577.1 )	response regulator in two-component regulatory system with PhoQ	NC_016078 (Pelagibacterium halotolerans B2)	2e-36	41
997) Shew185_0604   ( YP_001364828.1 )	two component transcriptional regulator	NC_009665 (Shewanella baltica OS185)	2e-36	41
998) Sbal195_0632   ( YP_001553070.1 )	two component transcriptional regulator	NC_009997 (Shewanella baltica OS195)	2e-36	41
999) Sbal678_0647   ( YP_005271884.1 )	two component transcriptional regulator, winged helix family	NC_016901 (Shewanella baltica OS678)	2e-36	41
1000) Cagg_3502   ( YP_002464777.1 )	winged helix family two component transcriptional regulator	NC_011831 (Chloroflexus aggregans DSM 9485)	2e-36	47
1001) Rcas_2599   ( YP_001432693.1 )	two component transcriptional regulator	NC_009767 (Roseiflexus castenholzii DSM 13941)	2e-36	47
1002) covR   ( YP_006903968.1 )	transcriptional regulator ycf27	NC_019042 (Streptococcus dysgalactiae AC-2713)	2e-36	43
1003) SDE12394_01880   ( YP_006012498.1 )	response regulator protein	NC_017567 (Streptococcus dysgalactiae ATCC 12394)	2e-36	43
1004) covR   ( YP_002996111.1 )	response regulator	NC_012891 (Streptococcus dysgalactiae GGS_124)	2e-36	43
1005) covR   ( YP_006859039.1 )	response regulator	NC_018712 (Streptococcus dysgalactiae RE378)	2e-36	43
1006) SPO1624   ( YP_166865.1 )	DNA-binding response regulator	NC_003911 (Ruegeria pomeroyi DSS-3)	2e-36	42
1007) Rsph17025_3971   ( YP_001170130.1 )	hypothetical protein	NC_009429 (Rhodobacter sphaeroides ATCC 17025)	3e-36	46
1008) SEQ_1890   ( YP_002747116.1 )	response regulator protein	NC_012471 (Streptococcus equi 4047)	3e-36	43
1009) covR   ( YP_006043688.1 )	TCS response regulator CovR-like protein	NC_017582 (Streptococcus equi ATCC 35246)	3e-36	43
1010) SZO_03070   ( YP_002743865.1 )	response regulator protein	NC_012470 (Streptococcus equi H70)	3e-36	43
1011) covR   ( YP_002124010.1 )	TCS response regulator CovR-like	NC_011134 (Streptococcus equi MGCS10565)	3e-36	43
1012) arlR   ( YP_006932371.1 )	response regulator	NC_018936 (Streptococcus pyogenes A20)	3e-36	43
1013) arlR   ( YP_006071477.1 )	response regulator	NC_017596 (Streptococcus pyogenes Alab49)	3e-36	43
1014) L897_01565   ( YP_008242599.1 )	PhoB family transcriptional regulator	NC_021807 (Streptococcus pyogenes HSC5)	3e-36	43
1015) covR   ( YP_007586876.1 )	response regulator	NC_020540 (Streptococcus pyogenes M1 476)	3e-36	43
1016) csrR   ( YP_001129096.1 )	response regulator protein	NC_009332 (Streptococcus pyogenes Manfredo)	3e-36	43
1017) covR   ( YP_597888.1 )	Response regulator CsrR	NC_008022 (Streptococcus pyogenes MGAS10270)	3e-36	43
1018) M6_Spy0310   ( YP_059628.1 )	response regulator CsrR	NC_006086 (Streptococcus pyogenes MGAS10394)	3e-36	43
1019) covR   ( YP_601771.1 )	Response regulator CsrR	NC_008024 (Streptococcus pyogenes MGAS10750)	3e-36	43
1020) covR   ( YP_005388362.1 )	TCS signal transduction response regulator CovR/CsrR	NC_017040 (Streptococcus pyogenes MGAS15252)	3e-36	43
1021) covR   ( YP_005411068.1 )	TCS signal transduction response regulator CovR/CsrR	NC_017053 (Streptococcus pyogenes MGAS1882)	3e-36	43
1022) csrR   ( NP_664048.1 )	two-component response regulator	NC_004070 (Streptococcus pyogenes MGAS315)	3e-36	43
1023) covR   ( YP_281646.1 )	response regulator	NC_007297 (Streptococcus pyogenes MGAS5005)	3e-36	43
1024) covR   ( YP_279743.1 )	response regulator	NC_007296 (Streptococcus pyogenes MGAS6180)	3e-36	43
1025) covR   ( YP_596014.1 )	response regulator	NC_008021 (Streptococcus pyogenes MGAS9429)	3e-36	43
1026) covR   ( NP_606584.1 )	CovR	NC_003485 (Streptococcus pyogenes MGAS8232)	3e-36	42
1027) Dfer_2762   ( YP_003087142.1 )	winged helix family two component transcriptional regulator	NC_013037 (Dyadobacter fermentans DSM 18053)	3e-36	41
1028) SPs1615   ( NP_802877.1 )	two-component response regulator CsrR/CovR	NC_004606 (Streptococcus pyogenes SSI-1)	4e-36	43
1029) BCO26_1272   ( YP_004568717.1 )	winged helix family two component transcriptional regulator	NC_015634 (Bacillus coagulans 2-6)	4e-36	42
1030) H04402_03509   ( YP_005680036.1 )	putative response regulator ArlR	NC_017299 (Clostridium botulinum H04402 065)	4e-36	42
1031) covR   ( YP_599896.1 )	response regulator CsrR	NC_008023 (Streptococcus pyogenes MGAS2096)	4e-36	42
1032) Strvi_4872   ( YP_004814706.1 )	winged helix family two component transcriptional regulator	NC_015957 (Streptomyces violaceusniger Tu 4113)	4e-36	42
1033) Arth_4535   ( YP_829285.1 )	two component transcriptional regulator	NC_008537 (Arthrobacter sp. FB24)	4e-36	41
1034) FAES_3074   ( YP_007321676.1 )	Transcriptional activator protein czcR	NC_020054 (Fibrella aestuarina BUZ 2)	4e-36	41
1035) HMPREF0946_00117   ( YP_008476395.1 )	hypothetical protein	NC_022196 (Fusobacterium sp. 3_1_36A2)	4e-36	41
1036) ragA   ( YP_001351979.1 )	two-components system response regulator	NC_009659 (Janthinobacterium sp. Marseille)	4e-36	41
1037) Tfu_1330   ( YP_289391.1 )	response regulator receiver	NC_007333 (Thermobifida fusca YX)	4e-36	41
1038) MASE_14620   ( YP_006748980.1 )	response regulator consisting of a CheY-like receiver domain-containing protein and a winged-helix DNA-binding domain-containing protein	NC_018632 (Alteromonas macleodii ATCC 27126)	4e-36	42
1039) AMBAS45_15135   ( YP_006803971.1 )	response regulator consisting of a CheY-like receiver domain-containing protein and a winged-helix DNA-binding domain-containing protein	NC_018679 (Alteromonas macleodii Balearic Sea AD45)	4e-36	42
1040) AMEC673_14890   ( YP_006800037.1 )	response regulator consisting of a CheY-like receiver domain-containing protein and a winged-helix DNA-binding domain-containing protein	NC_018678 (Alteromonas macleodii English Channel 673)	4e-36	42
1041) Bcoa_3255   ( YP_004861207.1 )	winged helix family two component transcriptional regulator	NC_016023 (Bacillus coagulans 36D1)	5e-36	43
1042) CtCNB1_0022   ( YP_003276064.1 )	two component transcriptional regulator	NC_013446 (Comamonas testosteroni CNB-1)	5e-36	42
1043) Lbuc_1782   ( YP_004399093.1 )	winged helix family two component transcriptional regulator	NC_015428 (Lactobacillus buchneri NRRL B-30929)	5e-36	41
1044) Noca_1598   ( YP_922799.1 )	response regulator receiver	NC_008699 (Nocardioides sp. JS614)	5e-36	41
1045) Shel_02200   ( YP_003142639.1 )	response regulator with CheY-like receiver domain and winged-helix DNA-binding domain	NC_013165 (Slackia heliotrinireducens DSM 20476)	6e-36	43
1046) csrR   ( YP_002285312.1 )	Response regulator CsrR	NC_011375 (Streptococcus pyogenes NZ131)	6e-36	43
1047) csrR   ( YP_002561732.1 )	response regulator protein	NC_012004 (Streptococcus uberis 0140J)	6e-36	43
1048) amad1_15475   ( YP_006977944.1 )	response regulator consisting of a CheY-like receiver domain-containing protein and a winged-helix DNA-binding domain-containing protein	NC_019393 (Alteromonas macleodii AltDE1)	6e-36	42
1049) MADE_1015535   ( YP_004428237.1 )	XRE family transcriptional regulator	NC_011138 (Alteromonas macleodii Deep ecotype)	6e-36	42
1050) I633_16000   ( YP_008193601.1 )	response regulator consisting of a CheY-like receiver domain-containing protein and a winged-helix DNA-binding domain-containing protein	NC_021716 (Alteromonas macleodii English Channel 615)	6e-36	42
1051) I607_14775   ( YP_008172998.1 )	response regulator consisting of a CheY-like receiver domain-containing protein and a winged-helix DNA-binding domain-containing protein	NC_021710 (Alteromonas macleodii Ionian Sea U4)	6e-36	42
1052) I876_15070   ( YP_008197396.1 )	response regulator consisting of a CheY-like receiver domain-containing protein and a winged-helix DNA-binding domain-containing protein	NC_021717 (Alteromonas macleodii Ionian Sea U7)	6e-36	42
1053) I634_15015   ( YP_008177100.1 )	response regulator consisting of a CheY-like receiver domain-containing protein and a winged-helix DNA-binding domain-containing protein	NC_021712 (Alteromonas macleodii Ionian Sea U8)	6e-36	42
1054) I636_14875   ( YP_008184935.1 )	response regulator consisting of a CheY-like receiver domain-containing protein and a winged-helix DNA-binding domain-containing protein	NC_021714 (Alteromonas macleodii Ionian Sea UM4b)	6e-36	42
1055) I635_15450   ( YP_008181003.1 )	response regulator consisting of a CheY-like receiver domain-containing protein and a winged-helix DNA-binding domain-containing protein	NC_021713 (Alteromonas macleodii Ionian Sea UM7)	6e-36	42
1056) BF638R_0158   ( YP_005109319.1 )	putative two-component response regulator transcriptional regulatory protein	NC_016776 (Bacteroides fragilis 638R)	6e-36	41
1057) BF0209   ( YP_097492.1 )	two-component system response regulator	NC_006347 (Bacteroides fragilis YCH46)	6e-36	41
1058) Phep_3673   ( YP_003093926.1 )	response regulator receiver	NC_013061 (Pedobacter heparinus DSM 2366)	6e-36	41
1059) Cri9333_4577   ( YP_007144867.1 )	winged helix family two component transcriptional regulator	NC_019753 (Crinalium epipsammum PCC 9333)	7e-36	41
1060) G655_22530   ( YP_007711345.1 )	two-component response regulator	NC_020912 (Pseudomonas aeruginosa B136-33)	7e-36	41
1061) PADK2_22825   ( YP_006484530.1 )	two-component response regulator	NC_018080 (Pseudomonas aeruginosa DK2)	7e-36	41
1062) PLES_47601   ( YP_002442341.1 )	putative two-component response regulator	NC_011770 (Pseudomonas aeruginosa LESB58)	7e-36	41
1063) PAM18_4472   ( YP_005977055.1 )	putative two-component response regulator	NC_017548 (Pseudomonas aeruginosa M18)	7e-36	41
1064) colR   ( YP_005979478.1 )	putative two-component response regulator	NC_017549 (Pseudomonas aeruginosa NCGM2.S1)	7e-36	41
1065) PA4381   ( NP_253071.1 )	two-component response regulator	NC_002516 (Pseudomonas aeruginosa PAO1)	7e-36	41
1066) M062_23085   ( YP_008135015.1 )	XRE family transcriptional regulator	NC_021577 (Pseudomonas aeruginosa RP73)	7e-36	41
1067) colR   ( YP_792726.1 )	two-component response regulator	NC_008463 (Pseudomonas aeruginosa UCBPP-PA14)	7e-36	41
1068) Acin_0192   ( YP_004895580.1 )	DNA-binding response regulator	NC_016077 (Acidaminococcus intestini RyC-MR95)	1e-35	44
1069) BCB4264_A0608   ( YP_002365368.1 )	DNA-binding response regulator	NC_011725 (Bacillus cereus B4264)	1e-35	43
1070) HD73_0642   ( YP_007419742.1 )	Two-component response regulator	NC_020238 (Bacillus cereus HD73)	1e-35	43
1071) SLGD_01509   ( YP_003471727.1 )	response regulator ArlR	NC_013893 (Staphylococcus lugdunensis HKU09-01)	1e-35	43
1072) arlR   ( YP_005760622.1 )	response regulator protein	NC_017353 (Staphylococcus lugdunensis N920143)	1e-35	43
1073) BC0572   ( NP_830389.1 )	two-component response regulator	NC_004722 (Bacillus cereus ATCC 14579 )	1e-35	42
1074) ykoG   ( YP_003596967.1 )	two-component response regulator	NC_014103 (Bacillus megaterium DSM 319)	1e-35	41
1075) BF0168   ( YP_209907.1 )	two-component response regulator transcriptional regulatory protein	NC_003228 (Bacteroides fragilis NCTC 9343)	1e-35	41
1076) PSPA7_4952   ( YP_001350288.1 )	putative two-component response regulator	NC_009656 (Pseudomonas aeruginosa PA7)	1e-35	41
1077) SSP1323   ( YP_301413.1 )	response regulator ArlR	NC_007350 (Staphylococcus saprophyticus ATCC 15305)	1e-35	41
1078) Ssal_01876   ( YP_006068977.1 )	response regulator	NC_017594 (Streptococcus salivarius 57.I)	1e-35	41
1079) rr01   ( YP_004727159.1 )	response regulator	NC_015760 (Streptococcus salivarius CCHSS3)	1e-35	41
1080) Taci_0717   ( YP_003317232.1 )	winged helix family two component transcriptional regulator	NC_013522 (Thermanaerovibrio acidaminovorans DSM 6589)	1e-35	41
1081) colR   ( YP_004713177.1 )	DNA-binding response regulator ColR	NC_015740 (Pseudomonas stutzeri ATCC 17588)	2e-35	43
1082) Cag_0440   ( YP_378756.1 )	two component transcriptional regulator	NC_007514 (Chlorobium chlorochromatii CaD3)	2e-35	41
1083) cusR   ( YP_007598259.1 )	two-component system, OmpR family, copper resistance phosphate regulon response regulator	NC_020548 (Azoarcus sp. KH32C)	8e-36	41
1084) ELI_1692   ( YP_003959641.1 )	two component transcriptional regulator	NC_014624 (Eubacterium limosum KIST612)	8e-36	41
1085) Slin_2552   ( YP_003387369.1 )	transcriptional regulator	NC_013730 (Spirosoma linguale DSM 74)	8e-36	41
1086) STP_1380   ( YP_004479500.1 )	response regulator protein	NC_015558 (Streptococcus parauberis KCTC 11537)	9e-36	42
1087) Niako_6386   ( YP_005012013.1 )	two component transcriptional regulator, winged helix family	NC_016609 (Niastella koreensis GR20-10)	9e-36	41
1088) SMUGS5_08600   ( YP_006490987.1 )	response regulator GcrR for glucan-binding protein C	NC_018089 (Streptococcus mutans GS-5)	9e-36	41
1089) AM1_1480   ( YP_001515822.1 )	two-component transcriptional regulator	NC_009925 (Acaryochloris marina MBIC11017)	2e-35	46
1090) Cyan7425_3411   ( YP_002484096.1 )	winged helix family two component transcriptional regulator	NC_011884 (Cyanothece sp. PCC 7425)	2e-35	46
1091) Acid345_0311   ( YP_589390.1 )	two component transcriptional regulator	NC_008009 (Candidatus Koribacter versatilis Ellin345)	2e-35	45
1092) Npun_R1688   ( YP_001865302.1 )	two component transcriptional regulator	NC_010628 (Nostoc punctiforme PCC 73102)	2e-35	45
1093) colR   ( YP_001171452.1 )	DNA-binding response regulator ColR	NC_009434 (Pseudomonas stutzeri A1501)	2e-35	44
1094) colR   ( YP_005937510.1 )	DNA-binding response regulator ColR	NC_017532 (Pseudomonas stutzeri DSM 4166)	2e-35	44
1095) BMB171_C0492   ( YP_003663030.1 )	two-component response regulator	NC_014171 (Bacillus thuringiensis BMB171)	2e-35	43
1096) Desmer_3712   ( YP_006623419.1 )	response regulator with CheY-like receiver domain and winged-helix DNA-binding domain	NC_018515 (Desulfosporosinus meridiei DSM 13257)	2e-35	43
1097) MLP_12950   ( YP_004571712.1 )	two-component system response regulator	NC_015635 (Microlunatus phosphovorus NM-1)	2e-35	43
1098) SCD_n01579   ( YP_008546432.1 )	response regulator	NC_022357 (Sulfuricella denitrificans skB26)	2e-35	43
1099) Emtol_3824   ( YP_006874977.1 )	two component transcriptional regulator, winged helix family	NC_018748 (Emticicia oligotrophica DSM 17448)	2e-35	42
1100) Ppha_0994   ( YP_002017895.1 )	winged helix family two component transcriptional regulator	NC_011060 (Pelodictyon phaeoclathratiforme BU-1)	2e-35	41
1101) ROP_pROB01-01890   ( YP_002776540.1 )	putative OmpR family two-component response regulator	NC_012520 (Rhodococcus opacus B4)	2e-35	41
1102) Ava_0615   ( YP_321134.1 )	two component transcriptional regulator	NC_007413 (Anabaena variabilis ATCC 29413)	3e-35	46
1103) BMD_5012   ( YP_003600162.1 )	two-component response regulator	NC_014103 (Bacillus megaterium DSM 319)	3e-35	44
1104) BMQ_5024   ( YP_003565437.1 )	two-component response regulator	NC_014019 (Bacillus megaterium QM B1551)	3e-35	44
1105) ykoG   ( YP_001486463.1 )	response regulator	NC_009848 (Bacillus pumilus SAFR-032)	3e-35	43
1106) Caur_2437   ( YP_001636035.1 )	response regulator receiver	NC_010175 (Chloroflexus aurantiacus J-10-fl)	3e-35	43
1107) Chy400_2626   ( YP_002570344.1 )	winged helix family two component transcriptional regulator	NC_012032 (Chloroflexus sp. Y-400-fl)	3e-35	43
1108) mprA   ( YP_002834360.1 )	two-component system response regulator	NC_012590 (Corynebacterium aurimucosum ATCC 700975)	3e-35	43
1109) Echvi_4209   ( YP_007226415.1 )	response regulator with CheY-like receiver domain and winged-helix DNA-binding domain	NC_019904 (Echinicola vietnamensis DSM 17526)	3e-35	43
1110) BSA_16850   ( YP_008085332.1 )	Response regulator CsrR	NC_021485 (Streptococcus agalactiae 09mas018883)	3e-35	42
1111) csrR   ( NP_688616.1 )	DNA-binding response regulator CsrR	NC_004116 (Streptococcus agalactiae 2603V/R)	3e-35	42
1112) csrR   ( YP_330242.1 )	DNA-binding response regulator CsrR	NC_007432 (Streptococcus agalactiae A909)	3e-35	42
1113) MSA_17510   ( YP_008087487.1 )	Response regulator CsrR	NC_021486 (Streptococcus agalactiae ILRI005)	3e-35	42
1114) SAIL_16780   ( YP_008118292.1 )	Response regulator CsrR	NC_021507 (Streptococcus agalactiae ILRI112)	3e-35	42
1115) gbs1672   ( NP_736107.1 )	DNA-binding response regulator CsrR	NC_004368 (Streptococcus agalactiae NEM316)	3e-35	42
1116) SBI_07380   ( YP_004965631.1 )	putative two-component system response regulator	NC_016582 (Streptomyces bingchenggensis BCW-1)	3e-35	42
1117) TKWG_08890   ( YP_006379104.1 )	winged helix family two component transcriptional regulator	NC_017964 (Advenella kashmirensis WT001)	3e-35	41
1118) Clim_1291   ( YP_001943337.1 )	winged helix family two component transcriptional regulator	NC_010803 (Chlorobium limicola DSM 245)	3e-35	43
1119) llrF   ( YP_893410.1 )	response regulator	NC_008600 (Bacillus thuringiensis Al Hakam)	3e-35	42
1120) csrR   ( YP_007969041.1 )	two-component response regulator	NC_021195 (Streptococcus agalactiae 2-22)	3e-35	42
1121) K710_1606   ( YP_008057301.1 )	response regulator protein	NC_021314 (Streptococcus iniae SF1)	3e-35	42
1122) Amet_1506   ( YP_001319359.1 )	two component transcriptional regulator	NC_009633 (Alkaliphilus metalliredigens QYMF)	4e-35	44
1123) Pse7367_2796   ( YP_007103477.1 )	winged helix family two component transcriptional regulator	NC_019701 (Pseudanabaena sp. PCC 7367)	4e-35	44
1124) Sfla_1927   ( YP_004922878.1 )	winged helix family two component transcriptional regulator	NC_016114 (Streptomyces flavogriseus ATCC 33331)	4e-35	44
1125) F750_4899   ( YP_007861821.1 )	two-component response regulator	NC_021055 (Streptomyces sp. PAMC26508)	4e-35	44
1126) TherJR_2129   ( YP_003640875.1 )	two component transcriptional regulator, winged helix family	NC_014152 (Thermincola potens JR)	4e-35	42
1127) arlR   ( YP_006951731.1 )	response regulator ArlR	NC_019048 (Streptococcus agalactiae SA20-06)	4e-35	41
1128) Y1U_C0299   ( YP_006339413.1 )	TCS response regulator CovR-like protein	NC_017927 (Streptococcus thermophilus MN-ZLW-002)	4e-35	41
1129) STND_0306   ( YP_006001878.1 )	TCS response regulator CovR-like protein	NC_017563 (Streptococcus thermophilus ND03)	4e-35	41
1130) Suden_0317   ( YP_392833.1 )	two component transcriptional regulator	NC_007575 (Sulfurimonas denitrificans ATCC 33889)	4e-35	41
1131) SYNPCC7002_G0158   ( YP_001733267.1 )	two-component response regulator; transcriptional regulatory protein	NC_010474 (Synechococcus sp. PCC 7002)	4e-35	41
1132) Dfer_0453   ( YP_003084887.1 )	winged helix family two component transcriptional regulator	NC_013037 (Dyadobacter fermentans DSM 18053)	5e-35	45
1133) ciaR   ( YP_006925241.1 )	transcriptional regulatory protein CiaR	NC_018877 (Bacillus thuringiensis Bt407)	5e-35	42
1134) CT43_CH0493   ( YP_005570476.1 )	two-component response regulator	NC_017208 (Bacillus thuringiensis CT-43)	5e-35	42
1135) H175_ch0496   ( YP_007476958.1 )	Two-component response regulator	NC_020376 (Bacillus thuringiensis IS5056)	5e-35	42
1136) Hbal_1278   ( YP_003059667.1 )	transcriptional regulator	NC_012982 (Hirschia baltica ATCC 59814)	5e-35	42
1137) Sama_3534   ( YP_929406.1 )	response regulator receiver protein	NC_008700 (Shewanella amazonensis SB2B)	6e-35	45
1138) AXY_16900   ( YP_006845584.1 )	two-component system response regulator	NC_018704 (Amphibacillus xylanus NBRC 15112)	6e-35	44
1139) BCG9842_B4731   ( YP_002444036.1 )	DNA-binding response regulator	NC_011772 (Bacillus cereus G9842)	6e-35	43
1140) BBR47_09580   ( YP_002770439.1 )	two-component response regulator	NC_012491 (Brevibacillus brevis NBRC 100599)	6e-35	42
1141) rr01   ( YP_140735.1 )	response regulator	NC_006449 (Streptococcus thermophilus CNRZ1066)	6e-35	41
1142) rr01   ( YP_006040112.1 )	response regulator	NC_017581 (Streptococcus thermophilus JIM 8232)	6e-35	41
1143) rr01   ( YP_138854.1 )	response regulator	NC_006448 (Streptococcus thermophilus LMG 18311)	6e-35	41
1144) B1NLA3E_19605   ( YP_007912164.1 )	two-component response regulator	NC_021171 (Bacillus sp. 1NLA3E)	8e-35	45
1145) Moth_1478   ( YP_430331.1 )	two component transcriptional regulator	NC_007644 (Moorella thermoacetica ATCC 39073)	1e-34	46
1146) MC28_5294   ( YP_006832115.1 )	hypothetical protein	NC_018693 (Bacillus thuringiensis MC28)	1e-34	43
1147) Acid_6895   ( YP_828093.1 )	two component transcriptional regulator	NC_008536 (Candidatus Solibacter usitatus Ellin6076)	1e-34	43
1148) Fbal_3729   ( YP_003914996.1 )	two component transcriptional regulator, winged helix family	NC_014541 (Ferrimonas balearica DSM 9799)	1e-34	43
1149) MASS_4881   ( YP_008025347.1 )	TcrA protein	NC_021282 (Mycobacterium abscessus 50594)	1e-34	43
1150) BCA_0602   ( YP_002747920.1 )	DNA-binding response regulator	NC_012472 (Bacillus cereus 03BB102)	1e-34	42
1151) llrF   ( YP_082091.1 )	response regulator	NC_006274 (Bacillus cereus E33L)	1e-34	42
1152) Dfer_0274   ( YP_003084709.1 )	winged helix family two component transcriptional regulator	NC_013037 (Dyadobacter fermentans DSM 18053)	1e-34	42
1153) Oweho_2064   ( YP_004989685.1 )	response regulator with CheY-like receiver domain and winged-helix DNA-binding domain	NC_016599 (Owenweeksia hongkongensis DSM 17368)	1e-34	42
1154) Thal_0320   ( YP_003473082.1 )	transcriptional regulator	NC_013894 (Thermocrinis albus DSM 14484)	1e-34	42
1155) Curi_c28350   ( YP_006789674.1 )	two component transcriptional regulator	NC_018664 (Clostridium acidurici 9a)	1e-34	41
1156) BTG_18305   ( YP_006605127.1 )	DNA-binding response regulator	NC_018500 (Bacillus thuringiensis HD-771)	7e-35	43
1157) BTF1_00570   ( YP_006608263.1 )	DNA-binding response regulator	NC_018508 (Bacillus thuringiensis HD-789)	7e-35	43
1158) BAnh1_03950   ( YP_007461065.1 )	two-component response regulator	NC_020300 (Bartonella australis Aust/NH1)	7e-35	42
1159) A964_1531   ( YP_006764732.1 )	DNA-binding response regulator CsrR	NC_018646 (Streptococcus agalactiae GD201008-001)	7e-35	42
1160) HM1_1535   ( YP_001680118.1 )	transcriptional regulator	NC_010337 (Heliobacterium modesticaldum Ice1)	8e-35	44
1161) Cagg_3265   ( YP_002464559.1 )	winged helix family two component transcriptional regulator	NC_011831 (Chloroflexus aggregans DSM 9485)	8e-35	42
1162) RC1_0686   ( YP_002296934.1 )	two-component transcriptional regulator	NC_011420 (Rhodospirillum centenum SW)	9e-35	52
1163) ragA   ( YP_007552699.1 )	two-component response regulator	NC_020516 (Azoarcus sp. KH32C)	9e-35	47
1164) Daud_1419   ( YP_001717558.1 )	two component transcriptional regulator	NC_010424 (Candidatus Desulforudis audaxviator MP104C)	9e-35	43
1165) SpiGrapes_2809   ( YP_005063575.1 )	response regulator with CheY-like receiver domain and winged-helix DNA-binding domain	NC_016633 (Sphaerochaeta pleomorpha Grapes)	9e-35	42
1166) Cha6605_0925   ( YP_007095709.1 )	response regulator with CheY-like receiver domain and winged-helix DNA-binding domain	NC_019697 (Chamaesiphon minutus PCC 6605)	1e-34	44
1167) GC56T3_1345   ( YP_003670948.1 )	winged helix family two component transcriptional regulator	NC_014206 (Geobacillus sp. C56-T3)	1e-34	43
1168) ykoG   ( YP_007402508.1 )	two-component sensor histidine kinase	NC_020210 (Geobacillus sp. GHH01)	1e-34	43
1169) GYMC52_2137   ( YP_004132682.1 )	two component transcriptional regulator, winged helix family	NC_014915 (Geobacillus sp. Y412MC52)	1e-34	43
1170) GYMC61_0523   ( YP_003251687.1 )	two component transcriptional regulator, winged helix family	NC_013411 (Geobacillus sp. Y412MC61)	1e-34	43
1171) RLO149_c040230   ( YP_004692884.1 )	two component signal transduction response regulator receiver protein	NC_015730 (Roseobacter litoralis Och 149)	1e-34	43
1172) llrF   ( YP_034830.1 )	response regulator	NC_005957 (Bacillus thuringiensis 97-27)	1e-34	42
1173) llh_8560   ( YP_005876311.1 )	Phosphate regulon transcriptional regulatory protein PhoB	NC_017492 (Lactococcus lactis A76)	1e-34	41
1174) kw2_0784   ( YP_008568429.1 )	two component system response regulator	NC_022369 (Lactococcus lactis KW2)	1e-34	41
1175) llrE   ( YP_006999271.1 )	two-component system regulator llrE	NC_019435 (Lactococcus lactis UC509.9)	1e-34	41
1176) colR   ( YP_008103548.1 )	two-component response regulator ColR	NC_021499 (Pseudomonas resinovorans NBRC 106553)	1e-34	41
1177) Mic7113_3510   ( YP_007122641.1 )	response regulator with CheY-like receiver domain and winged-helix DNA-binding domain	NC_019738 (Microcoleus sp. PCC 7113)	2e-34	46
1178) Acav_2295   ( YP_004234774.1 )	winged helix family two component transcriptional regulator	NC_015138 (Acidovorax avenae ATCC 19860)	2e-34	45
1179) Nos7107_1198   ( YP_007048998.1 )	winged helix family two component transcriptional regulator	NC_019676 (Nostoc sp. PCC 7107)	2e-34	45
1180) alr1194   ( NP_485237.1 )	two-component response regulator	NC_003272 (Nostoc sp. PCC 7120)	2e-34	45
1181) Riv7116_0912   ( YP_007054036.1 )	response regulator with CheY-like receiver domain and winged-helix DNA-binding domain	NC_019678 (Rivularia sp. PCC 7116)	2e-34	45
1182) BACI_c05810   ( YP_003790433.1 )	response regulator	NC_014335 (Bacillus cereus CI)	2e-34	43
1183) BCAH187_A0702   ( YP_002336705.1 )	DNA-binding response regulator	NC_011658 (Bacillus cereus AH187)	2e-34	42
1184) BCN_0549   ( YP_005103082.1 )	DNA-binding response regulator	NC_016771 (Bacillus cereus NC7401)	2e-34	42
1185) llrF   ( YP_002528382.1 )	response regulator	NC_011969 (Bacillus cereus Q1)	2e-34	42
1186) BcerKBAB4_0485   ( YP_001643379.1 )	two component transcriptional regulator	NC_010184 (Bacillus weihenstephanensis KBAB4)	2e-34	42
1187) Aazo_2223   ( YP_003721342.1 )	winged helix family two component transcriptional regulator	NC_014248 (Nostoc azollae 0708)	2e-34	42
1188) Osc7112_2406   ( YP_007115264.1 )	two component transcriptional regulator, winged helix family	NC_019729 (Oscillatoria nigro-viridis PCC 7112)	2e-34	42
1189) YBT020_03105   ( YP_005564288.1 )	DNA-binding response regulator	NC_017200 (Bacillus thuringiensis YBT-020)	2e-34	41
1190) SBI_07331   ( YP_004965582.1 )	two component transcriptional regulator, winged helix family protein	NC_016582 (Streptomyces bingchenggensis BCW-1)	2e-34	41
1191) Anacy_0517   ( YP_007155024.1 )	two component transcriptional regulator, winged helix family	NC_019771 (Anabaena cylindrica PCC 7122)	3e-34	43
1192) FraEuI1c_3975   ( YP_004017851.1 )	transcriptional regulator	NC_014666 (Frankia sp. EuI1c)	2e-34	44
1193) Haur_0804   ( YP_001543580.1 )	two component transcriptional regulator	NC_009972 (Herpetosiphon aurantiacus DSM 785)	2e-34	44
1194) Cyan7822_1300   ( YP_003886577.1 )	winged helix family two component transcriptional regulator	NC_014501 (Cyanothece sp. PCC 7822)	3e-34	44
1195) Dester_1148   ( YP_004281844.1 )	two component transcriptional regulator, winged helix family	NC_015185 (Desulfurobacterium thermolithotrophum DSM 11699)	3e-34	43
1196) GK2157   ( YP_148010.1 )	two-component response regulator	NC_006510 (Geobacillus kaustophilus HTA426)	3e-34	43
1197) GTCCBUS3UF5_24400   ( YP_004982843.1 )	Two-component response regulator	NC_016593 (Geobacillus thermoleovorans CCB_US3_UF5)	3e-34	43
1198) PHZ_c2688   ( YP_002131526.1 )	response regulator(with CheY-like receiver domain and winged-helix DNA-binding domain)	NC_011144 (Phenylobacterium zucineum HLK1)	3e-34	43
1199) SSIL_2104   ( YP_006462673.1 )	response regulator consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	NC_018065 (Solibacillus silvestris StLB046)	3e-34	43
1200) BAA_0654   ( YP_002865173.1 )	DNA-binding response regulator	NC_012659 (Bacillus anthracis A0248)	3e-34	42
1201) BA_0571   ( NP_843105.1 )	DNA-binding response regulator	NC_003997 (Bacillus anthracis Ames)	3e-34	42
1202) GBAA_0571   ( YP_017194.1 )	DNA-binding response regulator	NC_007530 (Bacillus anthracis Ames Ancestor)	3e-34	42
1203) BAMEG_4015   ( YP_002816567.1 )	DNA-binding response regulator	NC_012581 (Bacillus anthracis CDC 684)	3e-34	42
1204) H9401_0542   ( YP_006207596.1 )	Response regulator	NC_017729 (Bacillus anthracis H9401)	3e-34	42
1205) BAS0540   ( YP_026818.1 )	DNA-binding response regulator	NC_005945 (Bacillus anthracis Sterne)	3e-34	42
1206) BCK_05285   ( YP_006595166.1 )	Response regulator	NC_018491 (Bacillus cereus FRI-35)	3e-34	42
1207) Dacsa_1571   ( YP_007171606.1 )	response regulator with CheY-like receiver domain and winged-helix DNA-binding domain	NC_019780 (Dactylococcopsis salina PCC 8305)	3e-34	42
1208) GAU_2618   ( YP_002762130.1 )	OmpR family two-component response regulator	NC_012489 (Gemmatimonas aurantiaca T-27)	3e-34	42
1209) SH1490   ( YP_253405.1 )	hypothetical protein	NC_007168 (Staphylococcus haemolyticus JCSC1435)	3e-34	42
1210) FsymDg_1568   ( YP_004582949.1 )	winged helix family two component transcriptional regulator	NC_015656 (Frankia sp. 4085684)	3e-34	41
1211) Sta7437_2445   ( YP_007132946.1 )	two component transcriptional regulator, winged helix family	NC_019748 (Stanieria cyanosphaera PCC 7437)	3e-34	41
1212) Toce_0967   ( YP_003825352.1 )	two component transcriptional regulator, winged helix family	NC_014377 (Thermosediminibacter oceani DSM 16646)	3e-34	41
1213) Synpcc7942_1873   ( YP_400890.1 )	two component transcriptional regulator	NC_007604 (Synechococcus elongatus PCC 7942)	4e-34	45
1214) syc2221_c   ( YP_172931.1 )	two-component response regulator	NC_006576 (Synechococcus elongatus PCC6301)	4e-34	45
1215) Cha6605_6227   ( YP_007318430.1 )	response regulator with CheY-like receiver domain and winged-helix DNA-binding domain	NC_020053 (Chamaesiphon minutus PCC 6605)	4e-34	44
1216) Gbro_1324   ( YP_003272504.1 )	response regulator receiver	NC_013441 (Gordonia bronchialis DSM 43247)	4e-34	43
1217) bcf_02920   ( YP_005117243.1 )	Two-component response regulator, malate	NC_016779 (Bacillus cereus F837/76)	4e-34	42
1218) Celly_2950   ( YP_004263638.1 )	winged helix family two component transcriptional regulator	NC_015167 (Cellulophaga lytica DSM 7489)	4e-34	42
1219) Hprae_1473   ( YP_005836760.1 )	winged helix family two component transcriptional regulator	NC_017455 (Halanaerobium praevalens DSM 2228)	4e-34	42
1220) LBFF_1410   ( YP_007995586.1 )	Two component transcriptional regulator, winged helix family	NC_021235 (Lactobacillus fermentum F-6)	4e-34	42
1221) LAF_1298   ( YP_001844114.1 )	two-component response regulator	NC_010610 (Lactobacillus fermentum IFO 3956)	4e-34	42
1222) Mycch_4239   ( YP_006454633.1 )	response regulator with CheY-like receiver domain and winged-helix DNA-binding domain	NC_018027 (Mycobacterium chubuense NBB4)	4e-34	42
1223) Runsl_3552   ( YP_004657045.1 )	winged helix family two component transcriptional regulator	NC_015703 (Runella slithyformis DSM 19594)	4e-34	41
1224) PGA2_c12960   ( YP_006562548.1 )	two-component system response regulator	NC_018286 (Phaeobacter gallaeciensis 2.10)	5e-34	44
1225) PGA1_c13010   ( YP_006572737.1 )	two-component system response regulator	NC_018290 (Phaeobacter gallaeciensis DSM 17395)	5e-34	44
1226) Pjdr2_2638   ( YP_003011378.1 )	winged helix family two component transcriptional regulator	NC_012914 (Paenibacillus sp. JDR-2)	5e-34	43
1227) Emtol_2459   ( YP_006873622.1 )	two component transcriptional regulator, winged helix family	NC_018748 (Emticicia oligotrophica DSM 17448)	6e-34	45
1228) DCF50_p2776   ( YP_006914764.1 )	Response regulator receiver:Transcriptional regulatory protein-like protein	NC_018867 (Dehalobacter sp. CF)	1e-33	41
1229) DHBDCA_p2770   ( YP_006911782.1 )	Phosphate regulon transcriptional regulatory protein PhoB (SphR)	NC_018866 (Dehalobacter sp. DCA)	1e-33	41
1230) Saro_1631   ( YP_496905.1 )	two component transcriptional regulator	NC_007794 (Novosphingobium aromaticivorans DSM 12444)	1e-33	41
1231) SACTE_4594   ( YP_004804961.1 )	winged helix family two component transcriptional regulator	NC_015953 (Streptomyces sp. SirexAA-E)	5e-34	44
1232) BCAH820_0627   ( YP_002449600.1 )	DNA-binding response regulator	NC_011773 (Bacillus cereus AH820)	5e-34	42
1233) tcrA   ( YP_006266292.1 )	response regulator mprA	NC_017803 (Actinoplanes sp. SE50/110)	5e-34	41
1234) LACR_0898   ( YP_808869.1 )	DNA-binding response regulator	NC_008527 (Lactococcus lactis SK11)	5e-34	41
1235) Cal7507_0438   ( YP_007063767.1 )	winged helix family two component transcriptional regulator	NC_019682 (Calothrix sp. PCC 7507)	6e-34	44
1236) STH750   ( YP_074579.1 )	two-component response regulator	NC_006177 (Symbiobacterium thermophilum IAM 14863)	6e-34	44
1237) Cpha266_1205   ( YP_911664.1 )	two component transcriptional regulator	NC_008639 (Chlorobium phaeobacteroides DSM 266)	6e-34	43
1238) Riv7116_5064   ( YP_007058009.1 )	response regulator with CheY-like receiver domain and winged-helix DNA-binding domain	NC_019678 (Rivularia sp. PCC 7116)	6e-34	43
1239) PSPPH_3040   ( YP_275217.1 )	DNA-binding response regulator	NC_005773 (Pseudomonas syringae 1448A)	6e-34	42
1240) colR   ( YP_006717457.1 )	winged-helix transcriptional response regulator ColR	NC_007498 (Pelobacter carbinolicus DSM 2380)	6e-34	41
1241) RHA1_ro08012   ( YP_707217.1 )	response regulator, two-component system	NC_008269 (Rhodococcus jostii RHA1)	6e-34	41
1242) Daci_0726   ( YP_001561757.1 )	two component transcriptional regulator	NC_010002 (Delftia acidovorans SPH-1)	7e-34	45
1243) DelCs14_5811   ( YP_004491135.1 )	winged helix family two component transcriptional regulator	NC_015563 (Delftia sp. Cs1-4)	7e-34	45
1244) Theos_0482   ( YP_006971644.1 )	response regulator with CheY-like receiver domain and winged-helix DNA-binding domain	NC_019386 (Thermus oshimai JL-2)	7e-34	42
1245) Cyast_1744   ( YP_007165349.1 )	winged helix family two component transcriptional regulator	NC_019778 (Cyanobacterium stanieri PCC 7202)	7e-34	41
1246) Psyr_3127   ( YP_236197.1 )	response regulator receiver:transcriptional regulatory protein, C-terminal	NC_007005 (Pseudomonas syringae B728a)	7e-34	41
1247) Desku_2044   ( YP_004517400.1 )	winged helix family two component transcriptional regulator	NC_015573 (Desulfotomaculum kuznetsovii DSM 6115)	8e-34	47
1248) BN159_5879   ( YP_007524385.1 )	CheY-like receiver domain/winged-helix DNA-binding domain-containing response regulator	NC_020504 (Streptomyces davawensis JCM 4913)	8e-34	42
1249) CYA_2699   ( YP_476071.1 )	DNA-binding response regulator	NC_007775 (Synechococcus sp. JA-3-3Ab)	8e-34	42
1250) arlR   ( YP_188567.1 )	DNA-binding response regulator ArlR	NC_002976 (Staphylococcus epidermidis RP62A)	9e-34	44
1251) BCE_0634   ( NP_976960.1 )	DNA-binding response regulator	NC_003909 (Bacillus cereus ATCC 10987)	9e-34	42
1252) Bpet4611   ( YP_001633229.1 )	two-component response regulator	NC_010170 (Bordetella petrii DSM 12804)	1e-33	46
1253) Cal6303_3236   ( YP_007138149.1 )	winged helix family two component transcriptional regulator	NC_019751 (Calothrix sp. PCC 6303)	1e-33	45
1254) arlR   ( YP_005755318.1 )	response regulator ArlR	NC_017349 (Staphylococcus aureus LGA251)	1e-33	45
1255) Syn7502_03222   ( YP_007107234.1 )	response regulator with CheY-like receiver domain and winged-helix DNA-binding domain	NC_019702 (Synechococcus sp. PCC 7502)	1e-33	43
1256) Theco_2699   ( YP_007213787.1 )	response regulator with CheY-like receiver domain and winged-helix DNA-binding domain	NC_019897 (Thermobacillus composti KWC4)	1e-33	43
1257) Clos_2784   ( YP_001514311.1 )	two component transcriptional regulator	NC_009922 (Alkaliphilus oremlandii OhILAs)	1e-33	42
1258) BMQ_0215   ( YP_003560750.1 )	two-component response regulator	NC_014019 (Bacillus megaterium QM B1551)	1e-33	42
1259) llrF   ( YP_005497207.1 )	alkaline phosphatase synthesis transcriptional regulatory protein PhoP	NC_017138 (Bacillus megaterium WSH-002)	1e-33	42
1260) arlR   ( YP_006789451.1 )	two-component signal transduction response regulator	NC_018664 (Clostridium acidurici 9a)	1e-33	42
1261) Exig_2843   ( YP_001815306.1 )	two component transcriptional regulator	NC_010556 (Exiguobacterium sibiricum 255-15)	1e-33	42
1262) PputGB1_2876   ( YP_001669106.1 )	two component transcriptional regulator	NC_010322 (Pseudomonas putida GB-1)	1e-33	41
1263) BSA_21120   ( YP_008085757.1 )	DNA-binding response regulator	NC_021485 (Streptococcus agalactiae 09mas018883)	1e-33	41
1264) SAK_2061   ( YP_330651.1 )	DNA-binding response regulator	NC_007432 (Streptococcus agalactiae A909)	1e-33	41
1265) cusR   ( YP_006765160.1 )	DNA-binding response regulator	NC_018646 (Streptococcus agalactiae GD201008-001)	1e-33	41
1266) MSA_21720   ( YP_008087906.1 )	DNA-binding response regulator	NC_021486 (Streptococcus agalactiae ILRI005)	1e-33	41
1267) SAIL_21160   ( YP_008118728.1 )	DNA-binding response regulator	NC_021507 (Streptococcus agalactiae ILRI112)	1e-33	41
1268) tcrA   ( YP_007951899.1 )	two component transcriptional regulator, winged helix family protein	NC_021191 (Actinoplanes sp. N902-109)	2e-33	45
1269) Cylst_4172   ( YP_007148955.1 )	response regulator with CheY-like receiver domain and winged-helix DNA-binding domain	NC_019757 (Cylindrospermum stagnale PCC 7417)	2e-33	44
1270) SE1100   ( NP_764655.1 )	response regulator ArlR	NC_004461 (Staphylococcus epidermidis ATCC 12228)	2e-33	44
1271) Terro_4243   ( YP_006423782.1 )	response regulator with CheY-like receiver domain and winged-helix DNA-binding domain	NC_018014 (Terriglobus roseus DSM 18391)	2e-33	44
1272) B5T_04152   ( YP_006822755.1 )	two component transcriptional regulator, winged helix family	NC_018691 (Alcanivorax dieselolei B5)	2e-33	43
1273) Isova_2812   ( YP_004543395.1 )	two component transcriptional regulator, winged helix family	NC_015588 (Isoptericola variabilis 225)	2e-33	43
1274) BXY_02390   ( YP_007791101.1 )	two component transcriptional regulator, winged helix family	NC_021017 (Bacteroides xylanisolvens XB1A)	2e-33	42
1275) PCC7418_2986   ( YP_007169329.1 )	winged helix family two component transcriptional regulator	NC_019779 (Halothece sp. PCC 7418)	2e-33	42
1276) cheY   ( YP_007500504.1 )	two component transcriptional regulator, winged helix family, CheY	NC_020411 (Hydrogenobaculum sp. HO)	2e-33	42
1277) HydSN_1175   ( YP_007647562.1 )	response regulator with CheY-like receiver domain and winged-helix DNA-binding domain protein	NC_020814 (Hydrogenobaculum sp. SN)	2e-33	42
1278) Mycsm_06426   ( YP_007295982.1 )	response regulator with CheY-like receiver domain and winged-helix DNA-binding domain	NC_019966 (Mycobacterium smegmatis JS623)	2e-33	42
1279) Thit_2312   ( YP_003478080.1 )	winged helix family two component transcriptional regulator	NC_013921 (Thermoanaerobacter italicus Ab9)	2e-33	42
1280) Cyan10605_1850   ( YP_007161996.1 )	winged helix family two component transcriptional regulator	NC_019776 (Cyanobacterium aponinum PCC 10605)	2e-33	41
1281) ylcA   ( YP_006531125.1 )	two component transcriptional regulator	NC_018220 (Pseudomonas putida DOT-T1E)	2e-33	41
1282) L483_12720   ( YP_008094329.1 )	transcriptional regulator	NC_021491 (Pseudomonas putida H8234)	2e-33	41
1283) PP4_29120   ( YP_008113949.1 )	putative two-component response regulator	NC_021505 (Pseudomonas putida NBRC 14164)	2e-33	41
1284) PSPTO_3297   ( NP_793080.1 )	DNA-binding heavy metal response regulator	NC_004578 (Pseudomonas syringae DC3000)	2e-33	41
1285) RTCIAT899_PC00510   ( YP_007336459.1 )	two-component response regulator protein	NC_020062 (Rhizobium tropici CIAT 899)	2e-33	41
1286) GTNG_2092   ( YP_001126189.1 )	two-component response regulator	NC_009328 (Geobacillus thermodenitrificans NG80-2)	2e-33	43
1287) HMPREF0772_11792   ( YP_005747874.1 )	response regulator	NC_017342 (Staphylococcus aureus TCH60)	3e-33	44
1288) XNR_1434   ( YP_007744826.1 )	Two-component response regulator	NC_020990 (Streptomyces albus J1074)	3e-33	44
1289) Mflv_1887   ( YP_001133155.1 )	two component transcriptional regulator	NC_009338 (Mycobacterium gilvum PYR-GCK)	3e-33	42
1290) Mspyr1_12860   ( YP_004075801.1 )	response regulator with CheY-like receiver domain and winged-helix DNA-binding domain	NC_014814 (Mycobacterium gilvum Spyr1)	3e-33	42
1291) Mvan_4844   ( YP_955623.1 )	two component transcriptional regulator	NC_008726 (Mycobacterium vanbaalenii PYR-1)	3e-33	42
1292) Snas_4842   ( YP_003513576.1 )	winged helix family two component transcriptional regulator	NC_013947 (Stackebrandtia nassauensis DSM 44728)	3e-33	42
1293) phoB   ( YP_003779407.1 )	transcriptional regulator	NC_014328 (Clostridium ljungdahlii ATCC 49587)	3e-33	41
1294) PPUBIRD1_2829   ( YP_005930646.1 )	Winged helix family two component transcriptional regulator	NC_017530 (Pseudomonas putida BIRD-1)	3e-33	41
1295) Pput_2784   ( YP_001268100.1 )	two component transcriptional regulator	NC_009512 (Pseudomonas putida F1)	3e-33	41
1296) PP_2907   ( NP_745051.1 )	winged helix family two component transcriptional regulator	NC_002947 (Pseudomonas putida KT2440)	3e-33	41
1297) YSA_10035   ( YP_006389335.1 )	winged helix family two component transcriptional regulator	NC_017986 (Pseudomonas putida ND6)	3e-33	41
1298) B479_14940   ( YP_007229825.1 )	two component transcriptional regulator	NC_019905 (Pseudomonas putida PC9)	3e-33	41
1299) PPS_3004   ( YP_004702433.1 )	two component transcriptional regulator	NC_015733 (Pseudomonas putida S16)	3e-33	41
1300) PputW619_2409   ( YP_001749278.1 )	two component transcriptional regulator	NC_010501 (Pseudomonas putida W619)	3e-33	41
1301) BT_0682   ( NP_809595.1 )	two-component system response regulator	NC_004663 (Bacteroides thetaiotaomicron VPI-5482)	4e-33	42
1302) yycF   ( YP_006661441.1 )	transcriptional regulatory protein YycF	NC_018531 (Arthrobacter sp. Rue61a)	4e-33	41
1303) BMD_0209   ( YP_003595490.1 )	two-component response regulator	NC_014103 (Bacillus megaterium DSM 319)	4e-33	41
1304) Desca_2306   ( YP_004498053.1 )	winged helix family two component transcriptional regulator	NC_015565 (Desulfotomaculum carboxydivorans CO-1-SRB)	4e-33	41
1305) Q7A_2722   ( YP_006297153.1 )	two-component system regulatory protein	NC_017857 (Methylophaga sp. JAM1)	4e-33	41
1306) mprA1   ( YP_005959031.1 )	response regulator mprA Mycobacterial persistence regulator A	NC_017542 (Paenibacillus polymyxa M1)	4e-33	41
1307) PPSC2_c1525   ( YP_003945743.1 )	winged helix family two component transcriptional regulator	NC_014622 (Paenibacillus polymyxa SC2)	4e-33	41
1308) RTCIAT899_PA00570   ( YP_007335752.1 )	two-component response regulator protein	NC_020060 (Rhizobium tropici CIAT 899)	4e-33	41
1309) RB2501_02820   ( YP_003196784.1 )	two-component system response regulator	NC_013222 (Robiginitalea biformata HTCC2501)	5e-33	44
1310) SAMSHR1132_12560   ( YP_005325777.1 )	response regulator protein	NC_016941 (Staphylococcus aureus MSHR1132)	5e-33	44
1311) SGR_2135   ( YP_001823647.1 )	two-component system response regulator	NC_010572 (Streptomyces griseus NBRC 13350)	5e-33	44
1312) Dtox_1377   ( YP_003190876.1 )	two component transcriptional regulator, winged helix family	NC_013216 (Desulfotomaculum acetoxidans DSM 771)	5e-33	42
1313) M493_11090   ( REF_PRJNA208285:M493 )	PhoB family transcriptional regulator	NC_022080 (Geobacillus sp. JF8)	5e-33	42
1314) Awo_c27260   ( YP_005270368.1 )	response regulator	NC_016894 (Acetobacterium woodii DSM 1030)	5e-33	41
1315) Slin_1849   ( YP_003386693.1 )	transcriptional regulator	NC_013730 (Spirosoma linguale DSM 74)	5e-33	41
1316) Nos7524_1955   ( YP_007075411.1 )	response regulator with CheY-like receiver domain and winged-helix DNA-binding domain	NC_019684 (Nostoc sp. PCC 7524)	6e-33	45
1317) HY04AAS1_1151   ( YP_002121815.1 )	winged helix family two component transcriptional regulator	NC_011126 (Hydrogenobaculum sp. Y04AAS1)	6e-33	42
1318) Mnod_5481   ( YP_002500628.1 )	winged helix family two component transcriptional regulator	NC_011894 (Methylobacterium nodulans ORS 2060)	6e-33	42
1319) Aazo_0389   ( YP_003720073.1 )	winged helix family two component transcriptional regulator	NC_014248 (Nostoc azollae 0708)	6e-33	42
1320) AAur_1575   ( YP_947342.1 )	two-component system response regulator	NC_008711 (Arthrobacter aurescens TC1)	6e-33	41
1321) PFLU2572   ( YP_002872159.1 )	putative two-component response regulator transcriptional regulatory protein	NC_012660 (Pseudomonas fluorescens SBW25)	7e-33	42
1322) BH0372   ( NP_241238.1 )	two-component response regulator	NC_002570 (Bacillus halodurans C-125)	7e-33	41
1323) KN400_0424   ( YP_006889469.1 )	winged-helix transcriptional response regulator	NC_017454 (Geobacter sulfurreducens KN400)	1e-32	45
1324) GSU0451   ( NP_951510.1 )	winged-helix transcriptional response regulator	NC_002939 (Geobacter sulfurreducens PCA)	1e-32	45
1325) RoseRS_2290   ( YP_001276619.1 )	two component transcriptional regulator	NC_009523 (Roseiflexus sp. RS-1)	1e-32	45
1326) tcsR4   ( YP_005696251.1 )	two component system response regulator	NC_017308 (Corynebacterium pseudotuberculosis 1/06-A)	1e-32	44
1327) tcsR4   ( YP_005680931.1 )	two component system response regulator	NC_017300 (Corynebacterium pseudotuberculosis 1002)	1e-32	44
1328) tcsR4   ( YP_006352242.1 )	two component system response regulator	NC_017945 (Corynebacterium pseudotuberculosis 258)	1e-32	44
1329) tcsR4   ( YP_005843517.1 )	two component system response regulator	NC_017462 (Corynebacterium pseudotuberculosis 267)	1e-32	44
1330) tcsR4   ( YP_005122788.1 )	two component system response regulator	NC_016781 (Corynebacterium pseudotuberculosis 3/99-5)	1e-32	44
1331) tcsR4   ( YP_006213178.1 )	two component system response regulator	NC_017730 (Corynebacterium pseudotuberculosis 31)	1e-32	44
1332) tcsR4   ( YP_005692178.1 )	two component system response regulator	NC_017306 (Corynebacterium pseudotuberculosis 42/02-A)	1e-32	44
1333) tcsR4   ( YP_005683020.1 )	two component system response regulator	NC_017301 (Corynebacterium pseudotuberculosis C231)	1e-32	44
1334) tcsR4   ( YP_005694240.1 )	two component system response regulator	NC_017307 (Corynebacterium pseudotuberculosis CIP 52.97)	1e-32	44
1335) tcsR4   ( YP_006436809.1 )	two component system response regulator	NC_018019 (Corynebacterium pseudotuberculosis Cp162)	1e-32	44
1336) tcsR4   ( YP_003783061.1 )	two-component system transcriptional regulatory protein	NC_014329 (Corynebacterium pseudotuberculosis FRC41)	1e-32	44
1337) tcsR4   ( YP_005685107.1 )	two component system response regulator	NC_017303 (Corynebacterium pseudotuberculosis I19)	1e-32	44
1338) tcsR4   ( YP_005374695.1 )	two component system response regulator	NC_017031 (Corynebacterium pseudotuberculosis P54B96)	1e-32	44
1339) tcsR4   ( YP_005690112.1 )	two component system response regulator	NC_017305 (Corynebacterium pseudotuberculosis PAT10)	1e-32	44
1340) CULC0102_0815   ( YP_006494249.1 )	two-component system transcriptional regulatory protein	NC_018101 (Corynebacterium ulcerans 0102)	1e-32	44
1341) tcsR3   ( YP_005710333.1 )	two-component system transcriptional regulatory protein	NC_017317 (Corynebacterium ulcerans 809)	1e-32	44
1342) tcsR4   ( YP_004629347.1 )	two-component system transcriptional regulator	NC_015683 (Corynebacterium ulcerans BR-AD22)	1e-32	44
1343) Ppro_2957   ( YP_902612.1 )	two component transcriptional regulator	NC_008609 (Pelobacter propionicus DSM 2379)	1e-32	44
1344) KTR9_1310   ( YP_006668105.1 )	DNA-binding response regulator	NC_018581 (Gordonia sp. KTR9)	1e-32	43
1345) PPE_02222   ( YP_003870593.1 )	sensory transduction protein	NC_014483 (Paenibacillus polymyxa E681)	1e-32	43
1346) UWK_01389   ( YP_007467602.1 )	CheY-like receiver and winged-helix DNA-binding domain-containing response regulator	NC_020304 (Desulfocapsa sulfexigens DSM 10523)	1e-32	42
1347) GPOL_c12380   ( YP_005281662.1 )	two-component response regulator	NC_016906 (Gordonia polyisoprenivorans VH2)	1e-32	42
1348) Mycsm_05353   ( YP_007294950.1 )	response regulator with CheY-like receiver domain and winged-helix DNA-binding domain	NC_019966 (Mycobacterium smegmatis JS623)	1e-32	41
1349) Psta_3237   ( YP_003371761.1 )	winged helix family two component transcriptional regulator	NC_013720 (Pirellula staleyi DSM 6068)	1e-32	41
1350) FRAAL3821   ( YP_714024.1 )	response regulator in two-component regulatory system	NC_008278 (Frankia alni ACN14a)	2e-32	46
1351) H924_04175   ( YP_007530184.1 )	hypothetical protein	NC_020506 (Corynebacterium callunae DSM 20147)	8e-33	44
1352) Fluta_3889   ( YP_004346691.1 )	winged helix family two component transcriptional regulator	NC_015321 (Fluviicola taffensis DSM 16823)	8e-33	43
1353) Tmz1t_1940   ( YP_002355587.1 )	winged helix family two component transcriptional regulator	NC_011662 (Thauera sp. MZ1T)	8e-33	43
1354) PCC7424_2242   ( YP_002377532.1 )	winged helix family two component transcriptional regulator	NC_011729 (Cyanothece sp. PCC 7424)	8e-33	42
1355) PflA506_3038   ( YP_006324508.1 )	DNA-binding response regulator	NC_017911 (Pseudomonas fluorescens A506)	8e-33	42
1356) Lp16_1169   ( YP_008120999.1 )	two-component system response regulator	NC_021514 (Lactobacillus plantarum 16)	8e-33	41
1357) rrp5   ( YP_003062878.1 )	response regulator	NC_012984 (Lactobacillus plantarum JDM1)	8e-33	41
1358) rrp5   ( YP_003924531.1 )	response regulator	NC_014554 (Lactobacillus plantarum ST-III)	8e-33	41
1359) rrp5   ( YP_004889380.1 )	two-component system response regulator	NC_004567 (Lactobacillus plantarum WCFS1)	8e-33	41
1360) rrp5   ( YP_007414232.1 )	Two-component system response regulator	NC_020229 (Lactobacillus plantarum ZJ316)	8e-33	41
1361) Plim_2757   ( YP_003630779.1 )	response regulator receiver	NC_014148 (Planctomyces limnophilus DSM 3776)	9e-33	44
1362) arlR   ( YP_005742118.1 )	Putative response regulator ArlR	NC_017340 (Staphylococcus aureus 04-02981)	9e-33	44
1363) arlR   ( YP_006710192.1 )	response regulator protein	NC_018608 (Staphylococcus aureus 08BA02176)	9e-33	44
1364) arlR   ( YP_005757812.1 )	response regulator	NC_017351 (Staphylococcus aureus 11819-97)	9e-33	44
1365) SAAG_02023   ( YP_008449281.1 )	response regulator arlR	NC_022113 (Staphylococcus aureus 55/2053)	9e-33	44
1366) arlR   ( YP_008485317.1 )	two-component DNA-binding response regulator ArlR, putative	NC_022222 (Staphylococcus aureus 6850)	9e-33	44
1367) ST398NM01_1417   ( YP_006195497.1 )	ArlR	NC_017673 (Staphylococcus aureus 71193)	9e-33	44
1368) arlR   ( YP_008168323.1 )	Response regulator ArlR	NC_021670 (Staphylococcus aureus Bmb9393)	9e-33	44
1369) CA347_1354   ( YP_008128212.1 )	transcriptional regulatory , C terminal family protein	NC_021554 (Staphylococcus aureus CA-347)	9e-33	44
1370) SAKOR_01352   ( YP_008491540.1 )	Two-component response regulator arlR	NC_022226 (Staphylococcus aureus CN1)	9e-33	44
1371) arlR   ( YP_186303.1 )	DNA-binding response regulator ArlR	NC_002951 (Staphylococcus aureus COL)	9e-33	44
1372) ECTR2_1272   ( YP_005750002.1 )	response regulator	NC_017343 (Staphylococcus aureus ECT-R 2)	9e-33	44
1373) SAOV_1425c   ( YP_005736914.1 )	two-component response regulator	NC_017337 (Staphylococcus aureus ED133)	9e-33	44
1374) arlR   ( YP_003282307.1 )	DNA-binding response regulator ArlR	NC_013450 (Staphylococcus aureus ED98)	9e-33	44
1375) arlR   ( YP_494005.1 )	DNA-binding response regulator	NC_007793 (Staphylococcus aureus FPR3757)	9e-33	44
1376) arlR   ( YP_006237624.1 )	response regulator protein	NC_017763 (Staphylococcus aureus HO 5096 0412)	9e-33	44
1377) SaurJH1_1505   ( YP_001316641.1 )	response regulator receiver	NC_009632 (Staphylococcus aureus JH1)	9e-33	44
1378) SaurJH9_1476   ( YP_001246846.1 )	two component transcriptional regulator	NC_009487 (Staphylococcus aureus JH9)	9e-33	44
1379) arlR   ( YP_005744736.1 )	response regulator receiver	NC_017341 (Staphylococcus aureus JKD6008)	9e-33	44
1380) arlR   ( YP_005739431.1 )	response regulator receiver	NC_017338 (Staphylococcus aureus JKD6159)	9e-33	44
1381) M013TW_1362   ( YP_005297792.1 )	putative response regulator ArlR	NC_016928 (Staphylococcus aureus M013)	9e-33	44
1382) BN843_13310   ( YP_007868396.1 )	Putative response regulator ArlR	NC_021059 (Staphylococcus aureus M1)	9e-33	44
1383) arlR   ( YP_040829.1 )	response regulator protein	NC_002952 (Staphylococcus aureus MRSA252)	9e-33	44
1384) SAS1358   ( YP_043477.1 )	response regulator protein	NC_002953 (Staphylococcus aureus MSSA476)	9e-33	44
1385) SAHV_1403   ( YP_001441993.1 )	truncated response regulator	NC_009782 (Staphylococcus aureus Mu3)	9e-33	44
1386) truncated-arlR   ( NP_371939.1 )	hypothetical protein	NC_002758 (Staphylococcus aureus Mu50)	9e-33	44
1387) MW1305   ( NP_646122.1 )	truncated (putative response regulator ArlR	NC_003923 (Staphylococcus aureus MW2)	9e-33	44
1388) SAOUHSC_01420   ( YP_499946.1 )	DNA-binding response regulator	NC_007795 (Staphylococcus aureus NCTC 8325)	9e-33	44
1389) NWMN_1328   ( YP_001332362.1 )	two-component response regulator	NC_009641 (Staphylococcus aureus Newman)	9e-33	44
1390) arlR   ( YP_416748.1 )	two-component response regulator	NC_007622 (Staphylococcus aureus RF122)	9e-33	44
1391) arlR   ( YP_008587935.1 )	response regulator ArlR	NC_022443 (Staphylococcus aureus SA40)	9e-33	44
1392) arlR   ( YP_008585402.1 )	response regulator ArlR	NC_022442 (Staphylococcus aureus SA957)	9e-33	44
1393) arlR   ( YP_007583612.1 )	Response regulator ArlR	NC_020536 (Staphylococcus aureus ST228)	9e-33	44
1394) arlR   ( YP_007621326.1 )	Response regulator ArlR	NC_020566 (Staphylococcus aureus ST228)	9e-33	44
1395) arlR   ( YP_007623315.1 )	Response regulator ArlR	NC_020568 (Staphylococcus aureus ST228)	9e-33	44
1396) arlR   ( YP_007577625.1 )	Response regulator ArlR	NC_020529 (Staphylococcus aureus ST228 (isolate=10388))	9e-33	44
1397) arlR   ( YP_007619342.1 )	Response regulator ArlR	NC_020564 (Staphylococcus aureus ST228 (isolate=10497))	9e-33	44
1398) arlR   ( YP_007579634.1 )	Response regulator ArlR	NC_020532 (Staphylococcus aureus ST228 (isolate=15532))	9e-33	44
1399) arlR   ( YP_007581597.1 )	Response regulator ArlR	NC_020533 (Staphylococcus aureus ST228 (isolate=16035))	9e-33	44
1400) arlR   ( YP_007585578.1 )	Response regulator ArlR	NC_020537 (Staphylococcus aureus ST228 (isolate=18412))	9e-33	44
1401) SAPIG1417   ( YP_005734213.1 )	transcriptional regulatory protein ResD	NC_017333 (Staphylococcus aureus ST398)	9e-33	44
1402) SAT0131_01493   ( YP_005752672.1 )	Response regulator ArlR	NC_017347 (Staphylococcus aureus T0131)	9e-33	44
1403) arlR   ( YP_001575239.1 )	response regulator	NC_010079 (Staphylococcus aureus TCH1516)	9e-33	44
1404) arlR   ( YP_005731420.1 )	response regulator ArlR	NC_017331 (Staphylococcus aureus TW20)	9e-33	44
1405) SAVC_06325   ( YP_005290860.1 )	DNA-binding response regulator ArlR	NC_016912 (Staphylococcus aureus VC40)	9e-33	44
1406) HPL003_22685   ( YP_005077484.1 )	sensory transduction protein	NC_016641 (Paenibacillus terrae HPL-003)	9e-33	43
1407) H045_10815   ( YP_007397724.1 )	putative two-component response regulator transcriptional regulatory protein	NC_020209 (Pseudomonas poae RE*1-1-14)	9e-33	42
1408) PPE_01418   ( YP_003869796.1 )	sensory transduction protein	NC_014483 (Paenibacillus polymyxa E681)	9e-33	41
1409) GAU_2013   ( YP_002761525.1 )	OmpR family two-component response regulator	NC_012489 (Gemmatimonas aurantiaca T-27)	2e-32	46
1410) SFUL_5199   ( YP_007933977.1 )	two-component system response regulator	NC_021177 (Streptomyces fulvissimus DSM 40593)	2e-32	44
1411) R2APBS1_0088   ( YP_007588507.1 )	response regulator with CheY-like receiver domain and winged-helix DNA-binding domain	NC_020541 (Rhodanobacter sp. 2APBS1)	2e-32	43
1412) Caka_2013   ( YP_003549201.1 )	winged helix family two component transcriptional regulator	NC_014008 (Coraliomargarita akajimensis DSM 45221)	2e-32	42
1413) MTES_3011   ( YP_004225855.1 )	response regulator consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	NC_015125 (Microbacterium testaceum StLB037)	2e-32	42
1414) Cspa_c29570   ( YP_007455972.1 )	Two component transcriptional regulator, winged helix family	NC_020291 (Clostridium saccharoperbutylacetonicum N1-4(HMT))	2e-32	41
1415) Fraau_0777   ( YP_005376930.1 )	response regulator with CheY-like receiver domain and winged-helix DNA-binding domain	NC_017033 (Frateuria aurantia DSM 6220)	2e-32	41
1416) ZPR_1917   ( YP_003584438.1 )	two component transcriptional regulator winged helix family protein	NC_014041 (Zunongwangia profunda SMA-87)	2e-32	41
1417) tcsR4   ( YP_005303278.1 )	two component system response regulator	NC_016932 (Corynebacterium pseudotuberculosis 316)	3e-32	45
1418) CC_1293   ( NP_420106.1 )	DNA-binding response regulator	NC_002696 (Caulobacter crescentus CB15)	3e-32	43
1419) CCNA_01351   ( YP_002516724.1 )	two-component response regulator protein	NC_011916 (Caulobacter crescentus NA1000)	3e-32	43
1420) SC6G10.16   ( NP_626399.1 )	two component system response regulator	NC_003888 (Streptomyces coelicolor A3(2))	3e-32	43
1421) phoB   ( YP_002761871.1 )	phosphate regulon transcriptional regulatory protein PhoB	NC_012489 (Gemmatimonas aurantiaca T-27)	3e-32	42
1422) MDS_2290   ( YP_004380073.1 )	two component transcriptional regulator	NC_015410 (Pseudomonas mendocina NK-01)	3e-32	42
1423) LAC30SC_08995   ( YP_004292837.1 )	response regulator	NC_015214 (Lactobacillus acidophilus 30SC)	3e-32	41
1424) LEUM_1732   ( YP_819192.1 )	DNA-binding response regulator	NC_008531 (Leuconostoc mesenteroides ATCC 8293)	3e-32	41
1425) MI1_07485   ( YP_005174905.1 )	DNA-binding response regulator	NC_016805 (Leuconostoc mesenteroides J18)	3e-32	41
1426) L483_26840   ( YP_008097113.1 )	XRE family transcriptional regulator	NC_021491 (Pseudomonas putida H8234)	3e-32	41
1427) colR   ( YP_008111911.1 )	two-component response regulator ColR	NC_021505 (Pseudomonas putida NBRC 14164)	3e-32	41
1428) Gura_4293   ( YP_001233009.1 )	two component transcriptional regulator	NC_009483 (Geobacter uraniireducens Rf4)	3e-32	46
1429) colR   ( YP_005928841.1 )	ColR	NC_017530 (Pseudomonas putida BIRD-1)	3e-32	41
1430) irlR   ( YP_006532551.1 )	winged helix family two component	NC_018220 (Pseudomonas putida DOT-T1E)	3e-32	41
1431) Pput_0940   ( YP_001266285.1 )	two component transcriptional regulator	NC_009512 (Pseudomonas putida F1)	3e-32	41
1432) PputGB1_4486   ( YP_001670708.1 )	two component transcriptional regulator	NC_010322 (Pseudomonas putida GB-1)	3e-32	41
1433) colR   ( NP_743062.1 )	winged helix family two component transcriptional regulator	NC_002947 (Pseudomonas putida KT2440)	3e-32	41
1434) YSA_06895   ( YP_006387600.1 )	winged helix family two component transcriptional regulator	NC_017986 (Pseudomonas putida ND6)	3e-32	41
1435) B479_21780   ( YP_007231188.1 )	ColR	NC_019905 (Pseudomonas putida PC9)	3e-32	41
1436) PPS_4330   ( YP_004703743.1 )	two component winged helix family transcriptional regulator	NC_015733 (Pseudomonas putida S16)	3e-32	41
1437) PputW619_0969   ( YP_001747843.1 )	two component transcriptional regulator	NC_010501 (Pseudomonas putida W619)	3e-32	41
1438) Sde_3703   ( YP_529170.1 )	two component transcriptional regulator, winged helix family	NC_007912 (Saccharophagus degradans 2-40)	3e-32	41
1439) Gmet_3383   ( YP_006722337.1 )	winged-helix transcriptional response regulator	NC_007517 (Geobacter metallireducens GS-15)	4e-32	46
1440) A11Q_935   ( YP_007644758.1 )	putative 2-component transcriptional regulator	NC_020813 (Bdellovibrio exovorus JSS)	4e-32	44
1441) Geob_0409   ( YP_002535879.1 )	two component transcriptional regulator, winged helix family	NC_011979 (Geobacter daltonii FRC-32)	4e-32	44
1442) Glo7428_0146   ( YP_007125920.1 )	two component transcriptional regulator, winged helix family	NC_019745 (Gloeocapsa sp. PCC 7428)	4e-32	43
1443) Synpcc7942_1404   ( YP_400421.1 )	two component transcriptional regulator	NC_007604 (Synechococcus elongatus PCC 7942)	4e-32	43
1444) Cagg_1100   ( YP_002462446.1 )	winged helix family two component transcriptional regulator	NC_011831 (Chloroflexus aggregans DSM 9485)	4e-32	42
1445) mprA   ( YP_005125035.1 )	two-component system response regulator MprA	NC_016782 (Corynebacterium diphtheriae 241)	4e-32	42
1446) mprA   ( YP_005157570.1 )	two-component system response regulator MprA	NC_016799 (Corynebacterium diphtheriae 31A)	4e-32	42
1447) mprA   ( YP_005159904.1 )	two-component system response regulator MprA	NC_016800 (Corynebacterium diphtheriae BH8)	4e-32	42
1448) mprA   ( YP_005133309.1 )	two-component system response regulator MprA	NC_016785 (Corynebacterium diphtheriae CDCE 8392)	4e-32	42
1449) mprA   ( YP_005135568.1 )	two-component system response regulator MprA	NC_016786 (Corynebacterium diphtheriae HC01)	4e-32	42
1450) mprA   ( YP_005140085.1 )	two-component system response regulator MprA	NC_016788 (Corynebacterium diphtheriae HC04)	4e-32	42
1451) mprA   ( YP_005127248.1 )	two-component system response regulator MprA	NC_016783 (Corynebacterium diphtheriae INCA 402)	4e-32	42
1452) DIP0854   ( NP_939218.1 )	two component system response regulator	NC_002935 (Corynebacterium diphtheriae NCTC13129)	4e-32	42
1453) mprA   ( YP_005144642.1 )	two-component system response regulator MprA	NC_016790 (Corynebacterium diphtheriae VA01)	4e-32	42
1454) Mycsm_05264   ( YP_007294867.1 )	response regulator with CheY-like receiver domain and winged-helix DNA-binding domain	NC_019966 (Mycobacterium smegmatis JS623)	4e-32	42
1455) Solca_4392   ( YP_006258558.1 )	response regulator with CheY-like receiver domain and winged-helix DNA-binding domain	NC_017770 (Solitalea canadensis DSM 3403)	4e-32	42
1456) mprA   ( YP_006570072.1 )	Two-component system response regulator	NC_018289 (Mycobacterium smegmatis MC2 155)	4e-32	41
1457) PALO_08765   ( YP_007871713.1 )	sensory transduction protein RegX	NC_021064 (Propionibacterium avidum 44067)	4e-32	41
1458) Slin_0919   ( YP_003385770.1 )	transcriptional regulator	NC_013730 (Spirosoma linguale DSM 74)	4e-32	41
1459) Cgl0874   ( NP_600102.1 )	two-component system, response regulator	NC_003450 (Corynebacterium glutamicum ATCC 13032)	5e-32	43
1460) CgtR2   ( YP_007560098.1 )	two-component system, response regulator	NC_020519 (Corynebacterium glutamicum ATCC 13032)	5e-32	43
1461) C270_06020   ( YP_006796112.1 )	DNA-binding response regulator	NC_018673 (Leuconostoc carnosum JB16)	5e-32	42
1462) Pmen_2476   ( YP_001187964.1 )	two component transcriptional regulator	NC_009439 (Pseudomonas mendocina ymp)	5e-32	42
1463) Mjls_4681   ( YP_001072937.1 )	two component transcriptional regulator	NC_009077 (Mycobacterium sp. JLS)	5e-32	41
1464) Mkms_4387   ( YP_940368.1 )	two component transcriptional regulator	NC_008705 (Mycobacterium sp. KMS)	5e-32	41
1465) Mmcs_4301   ( YP_641462.1 )	two component transcriptional regulator	NC_008146 (Mycobacterium sp. MCS)	5e-32	41
1466) cusR   ( YP_007999912.1 )	transcriptional regulatory protein CusR	NC_021237 (Pseudomonas fluorescens CHA0)	5e-32	41
1467) PFL_2573   ( YP_259680.1 )	DNA-binding response regulator	NC_004129 (Pseudomonas protegens Pf-5)	5e-32	41
1468) Bd2575   ( NP_969378.1 )	2-component transcriptional regulator	NC_005363 (Bdellovibrio bacteriovorus HD100)	6e-32	45
1469) mprA   ( YP_005162225.1 )	two-component system response regulator MprA	NC_016801 (Corynebacterium diphtheriae C7 (beta))	6e-32	42
1470) mprA   ( YP_005164552.1 )	two-component system response regulator MprA	NC_016802 (Corynebacterium diphtheriae HC02)	6e-32	42
1471) mprA   ( YP_005137814.1 )	two-component system response regulator MprA	NC_016787 (Corynebacterium diphtheriae HC03)	6e-32	42
1472) mprA   ( YP_005142387.1 )	two-component system response regulator MprA	NC_016789 (Corynebacterium diphtheriae PW8)	6e-32	42
1473) cusR   ( YP_006372072.1 )	Response regulator consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	NC_017956 (Tistrella mobilis KA081020-065)	1e-31	46
1474) SCAB_28441   ( YP_003488502.1 )	two-component system response regulator	NC_013929 (Streptomyces scabiei 87.22)	1e-31	43
1475) CE0948   ( NP_737558.1 )	two-component system response regulator	NC_004369 (Corynebacterium efficiens YS-314)	1e-31	42
1476) glr2669   ( NP_925615.1 )	two-component response regulator	NC_005125 (Gloeobacter violaceus PCC 7421)	1e-31	42
1477) rpaB   ( YP_001018648.1 )	two-component response regulator	NC_008820 (Prochlorococcus marinus MIT 9303)	1e-31	42
1478) O5Y_20645   ( YP_008454674.1 )	two-component response regulator MprA	NC_022115 (Rhodococcus erythropolis CCM2595)	1e-31	42
1479) mprA   ( YP_002767845.1 )	two-component response regulator MprA	NC_012490 (Rhodococcus erythropolis PR4)	1e-31	42
1480) syc0151_d   ( YP_170861.1 )	two-component response regulator	NC_006576 (Synechococcus elongatus PCC6301)	1e-31	42
1481) Alide2_1769   ( YP_004387672.1 )	winged helix family two component transcriptional regulator	NC_015422 (Alicycliphilus denitrificans K601)	1e-31	41
1482) mprA   ( YP_008464535.1 )	two-component system response regulator	NC_022116 (Amycolatopsis mediterranei RB)	1e-31	41
1483) RAM_42795   ( YP_005536483.1 )	two-component system response regulator	NC_017186 (Amycolatopsis mediterranei S699)	1e-31	41
1484) mprA   ( YP_006554683.1 )	two-component system response regulator	NC_018266 (Amycolatopsis mediterranei S699)	1e-31	41
1485) mprA   ( YP_003770432.1 )	two-component system response regulator	NC_014318 (Amycolatopsis mediterranei U32)	1e-31	41
1486) BCA_2296   ( YP_002749570.1 )	DNA-binding response regulator	NC_012472 (Bacillus cereus 03BB102)	1e-31	41
1487) bcf_11095   ( YP_005118854.1 )	DNA-binding response regulator	NC_016779 (Bacillus cereus F837/76)	1e-31	41
1488) BALH_1972   ( YP_894794.1 )	DNA-binding response regulator	NC_008600 (Bacillus thuringiensis Al Hakam)	1e-31	41
1489) Caur_2863   ( YP_001636453.1 )	response regulator receiver	NC_010175 (Chloroflexus aurantiacus J-10-fl)	1e-31	41
1490) Chy400_3100   ( YP_002570805.1 )	winged helix family two component transcriptional regulator	NC_012032 (Chloroflexus sp. Y-400-fl)	1e-31	41
1491) Cst_c14420   ( YP_007373042.1 )	Two component transcriptional regulator, winged helix family	NC_020134 (Clostridium stercorarium DSM 8532)	1e-31	41
1492) Clst_1392   ( YP_007679470.1 )	response regulator	NC_020887 (Clostridium stercorarium DSM 8532)	1e-31	41
1493) Kfla_3513   ( YP_003381370.1 )	winged helix family two component transcriptional regulator	NC_013729 (Kribbella flavida DSM 17836)	1e-31	41
1494) rrp3   ( YP_001727678.1 )	response regulator	NC_010471 (Leuconostoc citreum KM20)	1e-31	41
1495) Pfl01_4498   ( YP_350226.1 )	two component transcriptional regulator	NC_007492 (Pseudomonas fluorescens Pf0-1)	1e-31	41
1496) Marme_0369   ( YP_004311505.1 )	transcriptional regulator	NC_015276 (Marinomonas mediterranea MMB-1)	2e-31	42
1497) Gbem_2672   ( YP_002139476.1 )	winged-helix transcriptional response regulator	NC_011146 (Geobacter bemidjiensis Bem)	7e-32	43
1498) Gbro_1396   ( YP_003272572.1 )	response regulator receiver	NC_013441 (Gordonia bronchialis DSM 43247)	7e-32	43
1499) LA2_09330   ( YP_004032568.1 )	response regulator	NC_014724 (Lactobacillus amylovorus GRL 1112)	7e-32	41
1500) LAB52_08315   ( YP_005854585.1 )	response regulator	NC_017470 (Lactobacillus amylovorus GRL1118)	7e-32	41
1501) MycrhN_3337   ( YP_005001077.1 )	response regulator with CheY-like receiver domain and winged-helix DNA-binding domain	NC_016604 (Mycobacterium rhodesiae NBB3)	7e-32	41
1502) qseB   ( YP_005518956.1 )	winged helix family two component transcriptional regulator	NC_017167 (Alicyclobacillus acidocaldarius Tc-4-1)	8e-32	44
1503) Cal6303_5206   ( YP_007140064.1 )	winged helix family two component transcriptional regulator	NC_019751 (Calothrix sp. PCC 6303)	8e-32	42
1504) PMN2A_1500   ( YP_292691.1 )	two component transcriptional regulator	NC_007335 (Prochlorococcus marinus NATL2A)	8e-32	42
1505) PputUW4_02690   ( YP_007029690.1 )	two component transcriptional regulator	NC_019670 (Pseudomonas sp. UW4)	8e-32	42
1506) SBI_02806   ( YP_004961058.1 )	two component transcriptional regulator, winged helix family protein	NC_016582 (Streptomyces bingchenggensis BCW-1)	8e-32	42
1507) Caur_2434   ( YP_001636032.1 )	response regulator receiver	NC_010175 (Chloroflexus aurantiacus J-10-fl)	8e-32	41
1508) Chy400_2623   ( YP_002570341.1 )	winged helix family two component transcriptional regulator	NC_012032 (Chloroflexus sp. Y-400-fl)	8e-32	41
1509) Rcas_2487   ( YP_001432585.1 )	two component transcriptional regulator	NC_009767 (Roseiflexus castenholzii DSM 13941)	9e-32	46
1510) cgtR2   ( YP_225165.1 )	two component response regulator	NC_006958 (Corynebacterium glutamicum ATCC 13032)	9e-32	43
1511) cgtR2   ( YP_008401005.1 )	two-component system, transcriptional response regulator	NC_022040 (Corynebacterium glutamicum MB001)	9e-32	43
1512) Desgi_2319   ( YP_007945414.1 )	response regulator with CheY-like receiver domain and winged-helix DNA-binding domain	NC_021184 (Desulfotomaculum gibsoniae DSM 7213)	9e-32	43
1513) Dtur_0537   ( YP_002352441.1 )	winged helix family two component transcriptional regulator	NC_011661 (Dictyoglomus turgidum DSM 6724)	9e-32	43
1514) NATL1_02061   ( YP_001014035.1 )	two-component response regulator	NC_008819 (Prochlorococcus marinus NATL1A)	9e-32	42
1515) rrp5   ( YP_003772871.1 )	two-component response regulator	NC_014319 (Leuconostoc gasicomitatum LMG 18811)	9e-32	41
1516) C269_07010   ( YP_006745725.1 )	two-component response regulator	NC_018631 (Leuconostoc gelidum JB7)	9e-32	41
1517) mprA1   ( YP_007034861.1 )	Response regulator	NC_019673 (Saccharothrix espanaensis DSM 44229)	9e-32	41
1518) AciX8_3939   ( YP_005059252.1 )	two component transcriptional regulator, winged helix family	NC_016631 (Granulicella mallensis MP5ACTX8)	1e-31	42
1519) GC56T3_2849   ( YP_003672368.1 )	winged helix family two component transcriptional regulator	NC_014206 (Geobacillus sp. C56-T3)	2e-31	44
1520) CL3_29720   ( YP_007810517.1 )	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	NC_021024 (butyrate-producing bacterium SM4/1)	2e-31	43
1521) CLDAP_00860   ( YP_005440023.1 )	putative OmpR family two-component response regulator	NC_017079 (Caldilinea aerophila DSM 14535)	2e-31	43
1522) nfa49640   ( YP_121180.1 )	two-component system response regulator	NC_006361 (Nocardia farcinica IFM 10152)	2e-31	43
1523) PSEBR_a3362   ( YP_004354686.1 )	OmpR family response regulator	NC_015379 (Pseudomonas brassicacearum NFM421)	2e-31	43
1524) Npun_R1903   ( YP_001865499.1 )	two component transcriptional regulator	NC_010628 (Nostoc punctiforme PCC 73102)	2e-31	42
1525) Runsl_3559   ( YP_004657052.1 )	winged helix family two component transcriptional regulator	NC_015703 (Runella slithyformis DSM 19594)	2e-31	42
1526) BAA_2274   ( YP_002866569.1 )	DNA-binding response regulator	NC_012659 (Bacillus anthracis A0248)	2e-31	41
1527) BA_2212   ( NP_844604.1 )	DNA-binding response regulator	NC_003997 (Bacillus anthracis Ames)	2e-31	41
1528) GBAA_2212   ( YP_018854.1 )	DNA-binding response regulator	NC_007530 (Bacillus anthracis Ames Ancestor)	2e-31	41
1529) BAMEG_2384   ( YP_002814982.1 )	DNA-binding response regulator	NC_012581 (Bacillus anthracis CDC 684)	2e-31	41
1530) BAS2056   ( YP_028319.1 )	DNA-binding response regulator	NC_005945 (Bacillus anthracis Sterne)	2e-31	41
1531) BCAH820_2240   ( YP_002451190.1 )	DNA-binding response regulator	NC_011773 (Bacillus cereus AH820)	2e-31	41
1532) BACI_c21680   ( YP_003791955.1 )	DNA-binding response regulator	NC_014335 (Bacillus cereus CI)	2e-31	41
1533) M493_14170   ( REF_PRJNA208285:M493 )	PhoP family transcriptional regulator	NC_022080 (Geobacillus sp. JF8)	2e-31	41
1534) GTNG_2656   ( YP_001126746.1 )	two-component response regulator	NC_009328 (Geobacillus thermodenitrificans NG80-2)	2e-31	41
1535) Mahau_0905   ( YP_004462925.1 )	winged helix family two component transcriptional regulator	NC_015520 (Mahella australiensis 50-1 BON)	2e-31	41
1536) AciPR4_2855   ( YP_004183617.1 )	winged helix family two component transcriptional regulator	NC_014963 (Terriglobus saanensis SP1PR4)	2e-31	41
1537) mprA   ( YP_008016096.1 )	two-component system, OmpR family, response regulator MprA	NC_021252 (Amycolatopsis orientalis HCCB10007)	3e-31	41
1538) rpaB   ( NP_898335.1 )	two-component response regulator	NC_005070 (Synechococcus sp. WH 8102)	3e-31	41
1539) AS9A_3568   ( YP_004494806.1 )	response regulator mprA	NC_015564 (Amycolicicoccus subflavus DQS3-9A1)	3e-31	42
1540) PSF113_2366   ( YP_005207772.1 )	DNA-binding response regulator	NC_016830 (Pseudomonas fluorescens F113)	3e-31	42
1541) RHA1_ro05622   ( YP_705560.1 )	response regulator (protein-glutamate methylesterase)	NC_008268 (Rhodococcus jostii RHA1)	3e-31	41
1542) Cwoe_4710   ( YP_003396498.1 )	two component transcriptional regulator	NC_013739 (Conexibacter woesei DSM 14684)	4e-31	43
1543) SFUL_5317   ( YP_007934095.1 )	Two component transcriptional regulator, winged helix family	NC_021177 (Streptomyces fulvissimus DSM 40593)	4e-31	43
1544) C624_05285   ( YP_008065772.1 )	hypothetical protein	NC_021351 (Corynebacterium glutamicum SCgG1)	4e-31	42
1545) C629_05285   ( YP_008068795.1 )	hypothetical protein	NC_021352 (Corynebacterium glutamicum SCgG2)	4e-31	42
1546) B005_2071   ( YP_006641174.1 )	two component system regulatory protein	NC_018524 (Nocardiopsis alba ATCC BAA-2165)	4e-31	42
1547) arlR   ( YP_006725940.1 )	two-component response regulator	NC_018610 (Lactobacillus buchneri CD034)	4e-31	41
1548) Lbuc_1195   ( YP_004398513.1 )	winged helix family two component transcriptional regulator	NC_015428 (Lactobacillus buchneri NRRL B-30929)	4e-31	41
1549) tll2364   ( NP_683154.1 )	two-component response regulator	NC_004113 (Thermosynechococcus elongatus BP-1)	4e-31	41
1550) Desru_3176   ( YP_004546673.1 )	response regulator receiver	NC_015589 (Desulfotomaculum ruminis DSM 2154)	5e-31	41
1551) Francci3_2401   ( YP_481497.1 )	two component transcriptional regulator	NC_007777 (Frankia sp. CcI3)	1e-30	46
1552) llrA   ( YP_006999852.1 )	two-component system regulator llrA	NC_019435 (Lactococcus lactis UC509.9)	1e-30	45
1553) Ksed_21520   ( YP_003149904.1 )	response regulator with CheY-like receiver domain and winged-helix DNA-binding domain	NC_013169 (Kytococcus sedentarius DSM 20547)	1e-30	43
1554) Cyan7425_1115   ( YP_002481861.1 )	winged helix family two component transcriptional regulator	NC_011884 (Cyanothece sp. PCC 7425)	1e-30	42
1555) Ple7327_3329   ( YP_007082104.1 )	response regulator with CheY-like receiver domain and winged-helix DNA-binding domain	NC_019689 (Pleurocapsa minor PCC 7327)	1e-30	42
1556) RoseRS_0188   ( YP_001274574.1 )	two component transcriptional regulator	NC_009523 (Roseiflexus sp. RS-1)	1e-30	41
1557) Syncc9605_2384   ( YP_382671.1 )	two component transcriptional regulator	NC_007516 (Synechococcus sp. CC9605)	1e-30	41
1558) ykoG   ( YP_003427192.1 )	DNA-binding response regulator	NC_013791 (Bacillus pseudofirmus OF4)	5e-31	43
1559) Cwoe_0293   ( YP_003392104.1 )	two component transcriptional regulator	NC_013739 (Conexibacter woesei DSM 14684)	5e-31	43
1560) O3I_037520   ( YP_006812425.1 )	response regulator with CheY-like receiver domain and winged-helix DNA-binding domain	NC_018681 (Nocardia brasiliensis HUJEG-1)	5e-31	43
1561) REQ_11640   ( YP_004005948.1 )	two component system response regulator	NC_014659 (Rhodococcus equi 103S)	5e-31	42
1562) DMR_02640   ( YP_002951641.1 )	OmpR family two-component response regulator	NC_012796 (Desulfovibrio magneticus RS-1)	5e-31	41
1563) Gobs_4693   ( YP_003411611.1 )	winged helix family two component transcriptional regulator	NC_013757 (Geodermatophilus obscurus DSM 43160)	5e-31	41
1564) Tpau_3286   ( YP_003648210.1 )	winged helix family two component transcriptional regulator	NC_014158 (Tsukamurella paurometabola DSM 20162)	6e-31	43
1565) Arth_1441   ( YP_830935.1 )	two component transcriptional regulator	NC_008541 (Arthrobacter sp. FB24)	6e-31	42
1566) regX   ( YP_005373771.1 )	Phosphate regulon transcriptional regulatory protein	NC_017030 (Corallococcus coralloides DSM 2259)	6e-31	42
1567) RoseRS_3818   ( YP_001278122.1 )	two component transcriptional regulator	NC_009523 (Roseiflexus sp. RS-1)	6e-31	42
1568) ACPL_2205   ( YP_006265170.1 )	winged helix family two component transcriptional regulator	NC_017803 (Actinoplanes sp. SE50/110)	6e-31	41
1569) H9401_2097   ( YP_006209151.1 )	DNA-binding response regulator	NC_017729 (Bacillus anthracis H9401)	6e-31	41
1570) BCE_2675   ( NP_978981.1 )	DNA-binding response regulator	NC_003909 (Bacillus cereus ATCC 10987)	6e-31	41
1571) Clocel_1852   ( YP_003843360.1 )	two component transcriptional regulator, winged helix family	NC_014393 (Clostridium cellulovorans 743B)	6e-31	41
1572) Ser39006_0084   ( YP_008520466.1 )	two component transcriptional regulator, winged helix family	NC_022268 (Serratia sp. ATCC 39006)	6e-31	41
1573) Slin_3454   ( YP_003388261.1 )	transcriptional regulator	NC_013730 (Spirosoma linguale DSM 74)	6e-31	41
1574) cgR_0988   ( YP_001137865.1 )	hypothetical protein	NC_009342 (Corynebacterium glutamicum R)	7e-31	42
1575) Syncc9902_0308   ( YP_376324.1 )	two component transcriptional regulator	NC_007513 (Synechococcus sp. CC9902)	7e-31	42
1576) CCU_10730   ( YP_007796105.1 )	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	NC_021018 (Coprococcus sp. ART55/1)	7e-31	41
1577) mprA   ( YP_002782877.1 )	two-component response regulator MprA	NC_012522 (Rhodococcus opacus B4)	7e-31	41
1578) SACE_0761   ( YP_001103028.1 )	two-component system response regulator	NC_009142 (Saccharopolyspora erythraea NRRL 2338)	7e-31	41
1579) tcsR5   ( YP_005868865.1 )	two-component system regulator	NC_017486 (Lactococcus lactis CV56)	8e-31	45
1580) llrA   ( NP_267750.1 )	two-component system regulator	NC_002662 (Lactococcus lactis IL1403)	8e-31	45
1581) llrA   ( YP_007508841.1 )	two-component system regulator	NC_020450 (Lactococcus lactis IO-1)	8e-31	45
1582) phoB   ( YP_006266235.1 )	Phosphate regulon transcriptional regulatory protein phoB	NC_017803 (Actinoplanes sp. SE50/110)	8e-31	43
1583) Ocepr_1581   ( YP_004058207.1 )	winged helix family two component transcriptional regulator	NC_014761 (Oceanithermus profundus DSM 14977)	8e-31	43
1584) ANT_09310   ( YP_004173565.1 )	OmpR family two-component response regulator	NC_014960 (Anaerolinea thermophila UNI-1)	8e-31	42
1585) Marky_1676   ( YP_004368521.1 )	two component transcriptional regulator, winged helix family	NC_015387 (Marinithermus hydrothermalis DSM 14884)	8e-31	42
1586) llh_4555   ( YP_005875510.1 )	two-component system regulator	NC_017492 (Lactococcus lactis A76)	9e-31	45
1587) kw2_1549   ( YP_008569192.1 )	two component system response regulator	NC_022369 (Lactococcus lactis KW2)	9e-31	45
1588) LACR_1701   ( YP_809619.1 )	DNA-binding response regulator	NC_008527 (Lactococcus lactis SK11)	9e-31	45
1589) rpaB   ( NP_895819.1 )	two-component response regulator	NC_005071 (Prochlorococcus marinus MIT 9313)	9e-31	42
1590) STAUR_7042   ( YP_003956625.1 )	winged helix family two component transcriptional regulator	NC_014623 (Stigmatella aurantiaca DW4/3-1)	9e-31	42
1591) SC8F4.07   ( NP_629542.1 )	two-component system response regulator	NC_003888 (Streptomyces coelicolor A3(2))	9e-31	42
1592) MCA2330   ( YP_114746.1 )	DNA-binding response regulator	NC_002977 (Methylococcus capsulatus Bath)	1e-30	46
1593) tcsR   ( YP_003354153.1 )	two-component system regulator	NC_013656 (Lactococcus lactis KF147)	1e-30	45
1594) ANT_28720   ( YP_004175498.1 )	OmpR family two-component response regulator	NC_014960 (Anaerolinea thermophila UNI-1)	1e-30	42
1595) DGo_CA2392   ( YP_006261777.1 )	Two component transcriptional regulator, winged helix family	NC_017790 (Deinococcus gobiensis I-0)	1e-30	42
1596) FBFL15_1953   ( YP_004844236.1 )	two component system response regulatory protein	NC_016001 (Flavobacterium branchiophilum FL-15)	1e-30	42
1597) LBPG_01273   ( YP_008447808.1 )	response regulator	NC_022112 (Lactobacillus paracasei 8700:2)	1e-30	42
1598) TSC_c21620   ( YP_004203314.1 )	response regulator	NC_014974 (Thermus scotoductus SA-01)	1e-30	42
1599) BBR47_03530   ( YP_002769834.1 )	two-component response regulator	NC_012491 (Brevibacillus brevis NBRC 100599)	1e-30	41
1600) Deipe_1997   ( YP_007181260.1 )	CheY-like receiver domain/winged-helix DNA-binding domain-containing response regulator	NC_019793 (Deinococcus peraridilitoris DSM 19664)	1e-30	41
1601) Deipr_0147   ( YP_004254938.1 )	two component transcriptional regulator, winged helix family	NC_015161 (Deinococcus proteolyticus MRP)	1e-30	41
1602) MASS_1068   ( YP_008021534.1 )	two component response transcriptional regulatory protein MprA	NC_021282 (Mycobacterium abscessus 50594)	1e-30	41
1603) MAB_1076   ( YP_001701820.1 )	Mycobacterial persistence regulator MrpA (two component response transcriptional regulatory protein)	NC_010397 (Mycobacterium abscessus ATCC 19977)	1e-30	41
1604) mprA   ( YP_006520346.1 )	response regulator mprA	NC_018150 (Mycobacterium abscessus GO 06)	1e-30	41
1605) Nham_0998   ( YP_576308.1 )	two component transcriptional regulator	NC_007964 (Nitrobacter hamburgensis X14)	1e-30	41
1606) Oscil6304_3555   ( YP_007087038.1 )	response regulator with CheY-like receiver domain and winged-helix DNA-binding domain	NC_019693 (Oscillatoria acuminata PCC 6304)	1e-30	41
1607) RHA1_ro00074   ( YP_700068.1 )	response regulator, two-component system	NC_008268 (Rhodococcus jostii RHA1)	1e-30	41
1608) SynRCC307_0250   ( YP_001226506.1 )	two-component system response regulator	NC_009482 (Synechococcus sp. RCC307)	1e-30	41
1609) llrA   ( YP_001032234.1 )	two-component system regulator llrA	NC_009004 (Lactococcus lactis MG1363)	2e-30	45
1610) LLNZ_04665   ( YP_006356342.1 )	two-component system regulator llrA	NC_017949 (Lactococcus lactis NZ9000)	2e-30	45
1611) LCGT_0429   ( YP_004778606.1 )	two-component response regulator	NC_015930 (Lactococcus garvieae ATCC 49156)	2e-30	44
1612) LCGL_0429   ( YP_005870173.1 )	two-component response regulator	NC_017490 (Lactococcus garvieae Lg2)	2e-30	44
1613) Dgeo_0195   ( YP_603667.1 )	two component transcriptional regulator	NC_008025 (Deinococcus geothermalis DSM 11300)	2e-30	42
1614) LSEI_2681   ( YP_807842.1 )	DNA-binding response regulator	NC_008526 (Lactobacillus casei ATCC 334)	2e-30	42
1615) LCBD_2899   ( YP_005860934.1 )	Two component transcriptional regulator, winged helix family	NC_017474 (Lactobacillus casei BD-II)	2e-30	42
1616) rrp2   ( YP_001988780.1 )	Response regulator	NC_010999 (Lactobacillus casei BL23)	2e-30	42
1617) LC2W_2873   ( YP_005857786.1 )	Two component transcriptional regulator, winged helix family	NC_017473 (Lactobacillus casei LC2W)	2e-30	42
1618) AM1_5663   ( YP_001519929.1 )	two-component transcriptional regulator	NC_009925 (Acaryochloris marina MBIC11017)	2e-30	41
1619) Acry_0311   ( YP_001233457.1 )	two component transcriptional regulator	NC_009484 (Acidiphilium cryptum JF-5)	2e-30	41
1620) ACMV_03420   ( YP_004282571.1 )	two-component response regulator	NC_015186 (Acidiphilium multivorum AIU301)	2e-30	41
1621) ompR   ( YP_003784950.1 )	transcriptional regulatory protein	NC_014330 (Brachyspira pilosicoli 95/1000)	2e-30	41
1622) B2904_orf946   ( YP_006707037.1 )	winged helix family two component transcriptional regulator	NC_018607 (Brachyspira pilosicoli B2904)	2e-30	41
1623) BPP43_00795   ( YP_007233772.1 )	transcriptional regulator	NC_019908 (Brachyspira pilosicoli P43/6/78)	2e-30	41
1624) WESB_1739   ( YP_006704292.1 )	transcriptional regulatory protein	NC_018604 (Brachyspira pilosicoli WesB)	2e-30	41
1625) Deima_0521   ( YP_004169845.1 )	winged helix family two component transcriptional regulator	NC_014958 (Deinococcus maricopensis DSM 21211)	2e-30	41
1626) OmpR   ( YP_001212381.1 )	response regulator	NC_009454 (Pelotomaculum thermopropionicum SI)	2e-30	41
1627) CYB_2561   ( YP_478755.1 )	DNA-binding response regulator	NC_007776 (Synechococcus sp. JA-2-3B'a(2-13))	2e-30	41
1628) Syn6312_2299   ( YP_007061957.1 )	response regulator with CheY-like receiver domain and winged-helix DNA-binding domain	NC_019680 (Synechococcus sp. PCC 6312)	2e-30	41
1629) pmrA   ( YP_003743392.1 )	two-component system response regulator	NC_014306 (Erwinia billingiae Eb661)	2e-30	42
1630) Rcas_0997   ( YP_001431123.1 )	two component transcriptional regulator	NC_009767 (Roseiflexus castenholzii DSM 13941)	2e-30	42
1631) PputUW4_01935   ( YP_007028945.1 )	two component transcriptional regulator	NC_019670 (Pseudomonas sp. UW4)	2e-30	41
1632) CYA_1392   ( YP_474826.1 )	DNA-binding response regulator	NC_007775 (Synechococcus sp. JA-3-3Ab)	2e-30	41
1633) Syn6312_0109   ( YP_007059906.1 )	response regulator with CheY-like receiver domain and winged-helix DNA-binding domain	NC_019680 (Synechococcus sp. PCC 6312)	3e-30	44
1634) Noca_1613   ( YP_922814.1 )	response regulator receiver	NC_008699 (Nocardioides sp. JS614)	3e-30	43
1635) CYB_0174   ( YP_476437.1 )	DNA-binding response regulator	NC_007776 (Synechococcus sp. JA-2-3B'a(2-13))	3e-30	43
1636) TCCBUS3UF1_5420   ( YP_005653664.1 )	Two component transcriptional regulator, winged helix	NC_017278 (Thermus sp. CCB_US3_UF1)	3e-30	43
1637) LOCK919_2933   ( YP_008201413.1 )	Response regulator	NC_021721 (Lactobacillus casei LOCK919)	3e-30	42
1638) ykoG   ( YP_006752883.1 )	transcriptional regulatory protein ykoG	NC_018641 (Lactobacillus casei W56)	3e-30	42
1639) LCAZH_2681   ( YP_003789717.1 )	OmpR family DNA-binding response regulator	NC_014334 (Lactobacillus casei Zhang)	3e-30	42
1640) Svir_32770   ( YP_003135074.1 )	response regulator with CheY-like receiver domain-containing protein and winged-helix DNA-binding domain-containing protein	NC_013159 (Saccharomonospora viridis DSM 43017)	3e-30	41
1641) Slit_0261   ( YP_003522890.1 )	transcriptional regulator	NC_013959 (Sideroxydans lithotrophicus ES-1)	3e-30	41
1642) Theos_0373   ( YP_006971545.1 )	response regulator with CheY-like receiver domain and winged-helix DNA-binding domain	NC_019386 (Thermus oshimai JL-2)	4e-30	43
1643) BCK_21610   ( YP_006598408.1 )	DNA-binding response regulator	NC_018491 (Bacillus cereus FRI-35)	4e-30	42
1644) A605_04345   ( YP_007464242.1 )	two component system response regulator	NC_020302 (Corynebacterium halotolerans YIM 70093)	4e-30	42
1645) Cyan7822_0012   ( YP_003885341.1 )	winged helix family two component transcriptional regulator	NC_014501 (Cyanothece sp. PCC 7822)	4e-30	42
1646) PCC8801_2302   ( YP_002372477.1 )	winged helix family two component transcriptional regulator	NC_011726 (Cyanothece sp. PCC 8801)	4e-30	42
1647) Cyan8802_2353   ( YP_003138063.1 )	winged helix family two component transcriptional regulator	NC_013161 (Cyanothece sp. PCC 8802)	4e-30	42
1648) Rfer_0510   ( YP_521793.1 )	two component transcriptional regulator	NC_007908 (Rhodoferax ferrireducens T118)	4e-30	42
1649) Anacy_2842   ( YP_007157184.1 )	two component transcriptional regulator, winged helix family	NC_019771 (Anabaena cylindrica PCC 7122)	4e-30	41
1650) Pse7367_1311   ( YP_007102033.1 )	winged helix family two component transcriptional regulator	NC_019701 (Pseudanabaena sp. PCC 7367)	4e-30	41
1651) Rxyl_2983   ( YP_645705.1 )	two component transcriptional regulator	NC_008148 (Rubrobacter xylanophilus DSM 9941)	4e-30	41
1652) Chro_4412   ( YP_007093675.1 )	winged helix family two component transcriptional regulator	NC_019695 (Chroococcidiopsis thermalis PCC 7203)	5e-30	41
1653) Lepto7376_1060   ( YP_007070265.1 )	winged helix family two component transcriptional regulator	NC_019683 (Leptolyngbya sp. PCC 7376)	4e-30	42
1654) Glo7428_1153   ( YP_007126886.1 )	two component transcriptional regulator, winged helix family	NC_019745 (Gloeocapsa sp. PCC 7428)	5e-30	42
1655) Mesil_2637   ( YP_003685994.1 )	winged helix family two component transcriptional regulator	NC_014212 (Meiothermus silvanus DSM 9946)	5e-30	42
1656) AORI_6131   ( YP_008015117.1 )	two-component system, OmpR family, response regulator	NC_021252 (Amycolatopsis orientalis HCCB10007)	5e-30	41
1657) CE0233   ( NP_736843.1 )	transcriptional regulator	NC_004369 (Corynebacterium efficiens YS-314)	5e-30	41
1658) Slip_0097   ( YP_003701462.1 )	winged helix family two component transcriptional regulator	NC_014220 (Syntrophothermus lipocalidus DSM 12680)	5e-30	41
1659) Chro_3608   ( YP_007092927.1 )	winged helix family two component transcriptional regulator	NC_019695 (Chroococcidiopsis thermalis PCC 7203)	6e-30	46
1660) PCC7424_4207   ( YP_002379445.1 )	winged helix family two component transcriptional regulator	NC_011729 (Cyanothece sp. PCC 7424)	6e-30	42
1661) BDI_1054   ( YP_001302442.1 )	two-component system response regulator	NC_009615 (Parabacteroides distasonis ATCC 8503)	6e-30	42
1662) vicR   ( YP_005005719.1 )	response regulator	NC_016605 (Pediococcus claussenii ATCC BAA-344)	6e-30	42
1663) Aave_3002   ( YP_971343.1 )	two component transcriptional regulator	NC_008752 (Acidovorax citrulli AAC00-1)	7e-30	45
1664) Svir_31270   ( YP_003134929.1 )	response regulator with CheY-like receiver domain-containing protein and winged-helix DNA-binding domain-containing protein	NC_013159 (Saccharomonospora viridis DSM 43017)	7e-30	43
1665) Oscil6304_2772   ( YP_007086299.1 )	response regulator with CheY-like receiver domain and winged-helix DNA-binding domain	NC_019693 (Oscillatoria acuminata PCC 6304)	7e-30	42
1666) Runsl_3699   ( YP_004657189.1 )	winged helix family two component transcriptional regulator	NC_015703 (Runella slithyformis DSM 19594)	7e-30	41
1667) MAE_22160   ( YP_001657230.1 )	OmpR family two-component response regulator	NC_010296 (Microcystis aeruginosa NIES-843)	8e-30	42
1668) Amico_1683   ( YP_003554523.1 )	winged helix family two component transcriptional regulator	NC_014011 (Aminobacterium colombiense DSM 12261)	8e-30	41
1669) phoB   ( YP_006721647.1 )	winged-helix phosphate transcriptional response regulator	NC_007517 (Geobacter metallireducens GS-15)	8e-30	41
1670) Cagg_0243   ( YP_002461627.1 )	winged helix family two component transcriptional regulator	NC_011831 (Chloroflexus aggregans DSM 9485)	9e-30	41
1671) AciX8_3596   ( YP_005058918.1 )	two component transcriptional regulator, winged helix family	NC_016631 (Granulicella mallensis MP5ACTX8)	9e-30	41
1672) Oter_1407   ( YP_001818292.1 )	two component transcriptional regulator	NC_010571 (Opitutus terrae PB90-1)	9e-30	41
1673) M446_6140   ( YP_001772847.1 )	two component transcriptional regulator	NC_010511 (Methylobacterium sp. 4-46)	1e-29	44
1674) PECL_433   ( YP_005004412.1 )	two-component response regulator	NC_016605 (Pediococcus claussenii ATCC BAA-344)	1e-29	43
1675) XNR_4737   ( YP_007748062.1 )	Two component system response regulator	NC_020990 (Streptomyces albus J1074)	1e-29	43
1676) Plut_1212   ( YP_375117.1 )	two component transcriptional regulator	NC_007512 (Chlorobium luteolum DSM 273)	1e-29	42
1677) GEI7407_2406   ( YP_007109933.1 )	winged helix family two component transcriptional regulator	NC_019703 (Geitlerinema sp. PCC 7407)	1e-29	42
1678) YM304_05570   ( YP_007562809.1 )	putative OmpR family two-component response regulator	NC_020520 (Ilumatobacter coccineum YM16-304)	1e-29	42
1679) BN6_04170   ( YP_007034621.1 )	Two-component system, response regulator of the winged helix family	NC_019673 (Saccharothrix espanaensis DSM 44229)	1e-29	42
1680) Sros_3423   ( YP_003339103.1 )	response regulator receiver protein	NC_013595 (Streptosporangium roseum DSM 43021)	1e-29	42
1681) TtJL18_0542   ( YP_006058234.1 )	response regulator with CheY-like receiver domain and winged-helix DNA-binding domain	NC_017587 (Thermus thermophilus JL-18)	1e-29	42
1682) Ththe16_1521   ( YP_005641047.1 )	winged helix family two component transcriptional regulator	NC_017272 (Thermus thermophilus SG0.5JP17-16)	1e-29	42
1683) Ava_1878   ( YP_322395.1 )	two component transcriptional regulator	NC_007413 (Anabaena variabilis ATCC 29413)	1e-29	41
1684) Cal7507_0470   ( YP_007063799.1 )	winged helix family two component transcriptional regulator	NC_019682 (Calothrix sp. PCC 7507)	1e-29	41
1685) Cylst_5088   ( YP_007149813.1 )	response regulator with CheY-like receiver domain and winged-helix DNA-binding domain	NC_019757 (Cylindrospermum stagnale PCC 7417)	1e-29	41
1686) Lepto7376_4129   ( YP_007073092.1 )	winged helix family two component transcriptional regulator	NC_019683 (Leptolyngbya sp. PCC 7376)	1e-29	41
1687) Npun_F5788   ( YP_001869029.1 )	two component transcriptional regulator	NC_010628 (Nostoc punctiforme PCC 73102)	1e-29	41
1688) Nos7107_4020   ( YP_007051723.1 )	winged helix family two component transcriptional regulator	NC_019676 (Nostoc sp. PCC 7107)	1e-29	41
1689) ycf27   ( NP_487862.1 )	two-component response regulator	NC_003272 (Nostoc sp. PCC 7120)	1e-29	41
1690) Nos7524_2769   ( YP_007076194.1 )	response regulator with CheY-like receiver domain and winged-helix DNA-binding domain	NC_019684 (Nostoc sp. PCC 7524)	1e-29	41
1691) mprA   ( YP_004909862.1 )	response regulator mprA	NC_016111 (Streptomyces cattleya NRRL 8057)	1e-29	41
1692) SCATT_03280   ( YP_006052221.1 )	two-component systen response regulator	NC_017586 (Streptomyces cattleya NRRL 8057)	1e-29	41
1693) Syn7502_03543   ( YP_007107515.1 )	response regulator with CheY-like receiver domain and winged-helix DNA-binding domain	NC_019702 (Synechococcus sp. PCC 7502)	1e-29	41
1694) slr0947   ( NP_441728.2 )	OmpR subfamily protein	NC_000911 (Synechocystis sp. PCC 6803)	1e-29	41
1695) Aazo_0581   ( YP_003720200.1 )	winged helix family two component transcriptional regulator	NC_014248 (Nostoc azollae 0708)	2e-29	41
1696) Cyan10605_2543   ( YP_007162667.1 )	winged helix family two component transcriptional regulator	NC_019776 (Cyanobacterium aponinum PCC 10605)	9e-30	41
1697) AM1_C0086   ( YP_001521533.1 )	two-component transcriptional regulator	NC_009928 (Acaryochloris marina MBIC11017)	2e-29	43
1698) HN6_00478   ( YP_005863546.1 )	two-component response regulator	NC_017481 (Lactobacillus salivarius CECT 5713)	2e-29	43
1699) NIES39_K03840   ( YP_005070568.1 )	two-component response regulator	NC_016640 (Arthrospira platensis NIES-39)	2e-29	42
1700) Sta7437_0712   ( YP_007131272.1 )	two component transcriptional regulator, winged helix family	NC_019748 (Stanieria cyanosphaera PCC 7437)	2e-29	42
1701) TTC1138   ( YP_005107.1 )	two-component response regulator	NC_005835 (Thermus thermophilus HB27)	2e-29	42
1702) TTHA1502   ( YP_144768.1 )	response regulator	NC_006461 (Thermus thermophilus HB8)	2e-29	42
1703) Osc7112_1866   ( YP_007114766.1 )	two component transcriptional regulator, winged helix family	NC_019729 (Oscillatoria nigro-viridis PCC 7112)	2e-29	41
1704) Riv7116_2381   ( YP_007055444.1 )	response regulator with CheY-like receiver domain and winged-helix DNA-binding domain	NC_019678 (Rivularia sp. PCC 7116)	2e-29	41
1705) SYNPCC7002_A0979   ( YP_001734238.1 )	two-component DNA binding response regulator	NC_010475 (Synechococcus sp. PCC 7002)	2e-29	41
1706) Tery_0954   ( YP_720817.1 )	two component transcriptional regulator	NC_008312 (Trichodesmium erythraeum IMS101)	2e-29	41
1707) PCA10_41140   ( YP_008104451.1 )	putative two-component response regulator	NC_021499 (Pseudomonas resinovorans NBRC 106553)	3e-29	44
1708) GYMC10_5092   ( YP_003245112.1 )	winged helix family two component transcriptional regulator	NC_013406 (Paenibacillus sp. Y412MC10)	3e-29	43
1709) BCB4264_A2673   ( YP_002367381.1 )	DNA-binding response regulator	NC_011725 (Bacillus cereus B4264)	3e-29	42
1710) Dalk_1128   ( YP_002430299.1 )	winged helix family two component transcriptional regulator	NC_011768 (Desulfatibacillum alkenivorans AK-01)	3e-29	41
1711) Desku_2811   ( YP_004518124.1 )	winged helix family two component transcriptional regulator	NC_015573 (Desulfotomaculum kuznetsovii DSM 6115)	3e-29	41
1712) Fbal_2799   ( YP_003914075.1 )	two component transcriptional regulator, winged helix family	NC_014541 (Ferrimonas balearica DSM 9799)	3e-29	41
1713) GM18_1481   ( YP_004198224.1 )	winged helix family two component transcriptional regulator	NC_014973 (Geobacter sp. M18)	3e-29	41
1714) Oscil6304_1792   ( YP_007085390.1 )	response regulator with CheY-like receiver domain and winged-helix DNA-binding domain	NC_019693 (Oscillatoria acuminata PCC 6304)	3e-29	41
1715) Synpcc7942_1453   ( YP_400470.1 )	two component transcriptional regulator	NC_007604 (Synechococcus elongatus PCC 7942)	3e-29	41
1716) phoP   ( YP_007325232.1 )	two-component response regulator	NC_020055 (Desulfovibrio hydrothermalis DSM 14728)	3e-29	42
1717) rdhD   ( YP_308450.1 )	DNA-binding response regulator	NC_007356 (Dehalococcoides sp. CBDB1)	3e-29	41
1718) KE3_1796   ( YP_008357063.1 )	phosphate regulon response regulator PhoB	NC_021900 (Streptococcus lutetiensis 033)	4e-29	46
1719) phoB   ( YP_004559888.1 )	OmpR family two component system phosphate regulon response regulator	NC_015600 (Streptococcus pasteurianus ATCC 43144)	4e-29	46
1720) BLASA_4966   ( YP_005331766.1 )	Two-component transcriptional regulator, CheY-like receiver domain	NC_016943 (Blastococcus saxobsidens DD2)	4e-29	45
1721) phoB   ( YP_005095450.1 )	phosphate regulon transcriptional regulatory protein PhoB (SphR)	NC_016749 (Streptococcus macedonicus ACA-DC 198)	4e-29	45
1722) SGR_5117   ( YP_001826629.1 )	two-component system response regulator	NC_010572 (Streptomyces griseus NBRC 13350)	4e-29	43
1723) BcerKBAB4_2492   ( YP_001645325.1 )	two component transcriptional regulator	NC_010184 (Bacillus weihenstephanensis KBAB4)	4e-29	42
1724) EFD32_0863   ( YP_006537230.1 )	response regulator	NC_018221 (Enterococcus faecalis D32)	4e-29	42
1725) OG1RF_10783   ( YP_005707840.1 )	response regulator	NC_017316 (Enterococcus faecalis OG1RF)	4e-29	42
1726) EFS1_0878   ( YP_007152670.1 )	two-component response regulator	NC_019770 (Enterococcus faecalis Symbioflor 1)	4e-29	42
1727) EF1050   ( NP_814783.1 )	DNA-binding response regulator	NC_004668 (Enterococcus faecalis V583)	4e-29	42
1728) ENT_30770   ( YP_007809098.1 )	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	NC_021023 (Enterococcus sp. 7L76)	4e-29	42
1729) OB3452   ( NP_694374.1 )	two-component response regulator	NC_004193 (Oceanobacillus iheyensis HTE831)	4e-29	42
1730) HMPREF9154_0201   ( YP_006510552.1 )	response regulator receiver domain-containing protein	NC_018142 (Propionibacterium propionicum F0230a)	4e-29	42
1731) Psest_3476   ( YP_007241595.1 )	response regulator with CheY-like receiver domain and winged-helix DNA-binding domain	NC_019936 (Pseudomonas stutzeri RCH2)	4e-29	42
1732) Cha6605_3811   ( YP_007098309.1 )	response regulator with CheY-like receiver domain and winged-helix DNA-binding domain	NC_019697 (Chamaesiphon minutus PCC 6605)	4e-29	41
1733) Lbys_3025   ( YP_003999040.1 )	winged helix family two component transcriptional regulator	NC_014655 (Leadbetterella byssophila DSM 17132)	4e-29	41
1734) Mic7113_1418   ( YP_007120703.1 )	response regulator with CheY-like receiver domain and winged-helix DNA-binding domain	NC_019738 (Microcoleus sp. PCC 7113)	4e-29	41
1735) Thewi_0550   ( YP_004819293.1 )	winged helix family two component transcriptional regulator	NC_015958 (Thermoanaerobacter wiegelii Rt8.B1)	4e-29	41
1736) HD73_3349   ( YP_007422448.1 )	putative sensory transduction protein ykoG	NC_020238 (Bacillus cereus HD73)	5e-29	42
1737) Desal_3695   ( YP_002993280.1 )	transcriptional regulator	NC_012881 (Desulfovibrio salexigens DSM 2638)	5e-29	42
1738) Thit_0454   ( YP_003476323.1 )	winged helix family two component transcriptional regulator	NC_013921 (Thermoanaerobacter italicus Ab9)	5e-29	42
1739) Tmath_0545   ( YP_003676311.1 )	winged helix family two component transcriptional regulator	NC_014209 (Thermoanaerobacter mathranii A3)	5e-29	42
1740) Cthe_0799   ( YP_001037227.1 )	two component transcriptional regulator	NC_009012 (Clostridium thermocellum ATCC 27405)	5e-29	41
1741) Clo1313_1423   ( YP_005687936.1 )	winged helix family two component transcriptional regulator	NC_017304 (Clostridium thermocellum DSM 1313)	5e-29	41
1742) UCYN_09310   ( YP_003421993.1 )	winged helix family two component transcriptional regulator	NC_013771 (Cyanobacterium sp. UCYN-A)	5e-29	41
1743) A458_17275   ( YP_006459103.1 )	DNA-binding response regulator	NC_018028 (Pseudomonas stutzeri CCUG 29243)	5e-29	41
1744) Rcas_4351   ( YP_001434393.1 )	two component transcriptional regulator	NC_009767 (Roseiflexus castenholzii DSM 13941)	5e-29	41
1745) Rmet_5331   ( YP_587459.1 )	transcriptional regulator two components regulatory system	NC_007974 (Cupriavidus metallidurans CH34)	6e-29	41
1746) rpaB   ( YP_005383596.1 )	OmpR subfamily protein Ycf27/Rre26	NC_017038 (Synechocystis sp. PCC 6803)	6e-29	41
1747) rpaB   ( YP_005386765.1 )	OmpR subfamily protein Ycf27/Rre26	NC_017039 (Synechocystis sp. PCC 6803)	6e-29	41
1748) rpaB   ( YP_005409472.1 )	OmpR subfamily protein Ycf27/Rre26	NC_017052 (Synechocystis sp. PCC 6803)	6e-29	41
1749) rpaB   ( YP_005651787.1 )	OmpR subfamily protein Ycf27/Rre26	NC_017277 (Synechocystis sp. PCC 6803)	6e-29	41
1750) MYO_118510   ( YP_007451610.1 )	OmpR subfamily	NC_020286 (Synechocystis sp. PCC 6803)	6e-29	41
1751) SFUL_3399   ( YP_007932213.1 )	Two-component system response regulator	NC_021177 (Streptomyces fulvissimus DSM 40593)	7e-29	41
1752) CK1_38270   ( YP_007785178.1 )	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	NC_021014 (Ruminococcus sp. SR1/5)	1e-28	45
1753) Cha6605_4787   ( YP_007099229.1 )	response regulator with CheY-like receiver domain and winged-helix DNA-binding domain	NC_019697 (Chamaesiphon minutus PCC 6605)	1e-28	43
1754) Desti_3534   ( YP_006448448.1 )	response regulator with CheY-like receiver domain and winged-helix DNA-binding domain	NC_018025 (Desulfomonile tiedjei DSM 6799)	1e-28	42
1755) SAV_4416   ( NP_825593.1 )	two-component system response regulator	NC_003155 (Streptomyces avermitilis MA-4680)	1e-28	42
1756) Desku_1201   ( YP_004516585.1 )	winged helix family two component transcriptional regulator	NC_015573 (Desulfotomaculum kuznetsovii DSM 6115)	1e-28	41
1757) EFAU004_01286   ( YP_005354488.1 )	DNA-binding response regulator	NC_017022 (Enterococcus faecium Aus0004)	1e-28	41
1758) EFAU085_01051   ( YP_008394574.1 )	DNA-binding response regulator	NC_021994 (Enterococcus faecium AUS0085)	1e-28	41
1759) HMPREF0351_11007   ( YP_006375613.1 )	response regulator	NC_017960 (Enterococcus faecium DO)	1e-28	41
1760) M7W_1482   ( YP_007394165.1 )	DNA-binding heavy metal response regulator	NC_020207 (Enterococcus faecium NRRL B-2354)	1e-28	41
1761) TepRe1_2606   ( YP_004462011.1 )	winged helix family two component transcriptional regulator	NC_015519 (Tepidanaerobacter acetatoxydans Re1)	1e-28	41
1762) walR   ( YP_008619326.1 )	two-component response regulator [YycF]	NC_019954 (Tepidanaerobacter acetatoxydans Re1)	1e-28	41
1763) Thebr_1841   ( YP_004186759.1 )	response regulator receiver	NC_014964 (Thermoanaerobacter brockii Ako-1)	1e-28	41
1764) Teth39_1796   ( YP_001665769.1 )	two component transcriptional regulator	NC_010321 (Thermoanaerobacter pseudethanolicus ATCC 33223)	1e-28	41
1765) Thet_0487   ( YP_003903427.1 )	winged helix family two component transcriptional regulator	NC_014538 (Thermoanaerobacter sp. X513)	1e-28	41
1766) Teth514_0439   ( YP_001662085.1 )	two component transcriptional regulator	NC_010320 (Thermoanaerobacter sp. X514)	1e-28	41
1767) Glov_1807   ( YP_001952043.1 )	winged helix family two component transcriptional regulator	NC_010814 (Geobacter lovleyi SZ)	7e-29	42
1768) B737_5018   ( YP_008461350.1 )	two-component system response regulator	NC_022116 (Amycolatopsis mediterranei RB)	8e-29	41
1769) RAM_25860   ( YP_005533107.1 )	two-component system response regulator	NC_017186 (Amycolatopsis mediterranei S699)	8e-29	41
1770) AMES_5018   ( YP_006551499.1 )	two-component system response regulator	NC_018266 (Amycolatopsis mediterranei S699)	8e-29	41
1771) AMED_5078   ( YP_003767245.1 )	two-component system response regulator	NC_014318 (Amycolatopsis mediterranei U32)	8e-29	41
1772) ECBG_02950   ( YP_007753450.1 )	DNA-binding response regulator	NC_020995 (Enterococcus casseliflavus EC20)	8e-29	41
1773) EHR_13985   ( YP_006488537.1 )	DNA-binding response regulator	NC_018081 (Enterococcus hirae ATCC 9790)	8e-29	41
1774) PALO_00550   ( YP_007870105.1 )	response regulator MprA	NC_021064 (Propionibacterium avidum 44067)	8e-29	41
1775) csrR   ( YP_006992874.2 )	response regulator	NC_019425 (Carnobacterium maltaromaticum LMA28)	9e-29	42
1776) MycrhN_4371   ( YP_005002085.1 )	response regulator with CheY-like receiver domain and winged-helix DNA-binding domain	NC_016604 (Mycobacterium rhodesiae NBB3)	9e-29	41
1777) phoB   ( YP_007373793.1 )	phosphate regulon transcriptional regulatory protein PhoB	NC_020134 (Clostridium stercorarium DSM 8532)	1e-28	44
1778) Clst_2126   ( YP_007680172.1 )	response regulator	NC_020887 (Clostridium stercorarium DSM 8532)	1e-28	44
1779) ambt_01885   ( YP_004465733.1 )	response regulator consisting of a CheY-like receiver domain-containing protein and a winged-helix DNA-binding domain-containing protein	NC_015554 (Alteromonas sp. SN2)	2e-28	43
1780) OmpR   ( YP_001211000.1 )	response regulator	NC_009454 (Pelotomaculum thermopropionicum SI)	2e-28	43
1781) Deba_1066   ( YP_003807028.1 )	two component transcriptional regulator, winged helix family	NC_014365 (Desulfarculus baarsii DSM 2075)	2e-28	41
1782) Gbem_1846   ( YP_002138656.1 )	winged-helix transcriptional response regulator	NC_011146 (Geobacter bemidjiensis Bem)	2e-28	41
1783) GOX0395   ( YP_190834.1 )	DNA binding response regulator	NC_006677 (Gluconobacter oxydans 621H)	2e-28	41
1784) PSEBR_a2505   ( YP_004353788.1 )	two component regulator system response regulator PmrA	NC_015379 (Pseudomonas brassicacearum NFM421)	2e-28	41
1785) qseB   ( YP_005208482.1 )	protein QseB	NC_016830 (Pseudomonas fluorescens F113)	2e-28	41
1786) Q7S_02365   ( YP_005400305.1 )	DNA-binding transcriptional regulator BasR	NC_017047 (Rahnella aquatilis HX2)	2e-28	41
1787) Rahaq_0475   ( YP_004211231.1 )	transcriptional regulator	NC_015061 (Rahnella sp. Y9602)	2e-28	41
1788) Srot_3063   ( YP_003660318.1 )	transcriptional regulator	NC_014168 (Segniliparus rotundus DSM 44985)	2e-28	41
1789) F504_4157   ( YP_008237886.1 )	DNA-binding heavy metal response regulator	NC_021745 (Ralstonia solanacearum FQY_4)	3e-28	43
1790) RSp1042   ( NP_522603.1 )	two-component response regulator transcription regulator protein	NC_003296 (Ralstonia solanacearum GMI1000)	3e-28	43
1791) Ppro_3752   ( YP_899596.1 )	two component transcriptional regulator	NC_008607 (Pelobacter propionicus DSM 2379)	3e-28	41
1792) BurJV3_2468   ( YP_004793014.1 )	two component winged helix family transcriptional regulator	NC_015947 (Stenotrophomonas maltophilia JV3)	3e-28	41
1793) Acfer_0126   ( YP_003397850.1 )	two component transcriptional regulator, winged helix family	NC_013740 (Acidaminococcus fermentans DSM 20731)	3e-28	44
1794) Dgeo_2749   ( YP_594256.1 )	two component transcriptional regulator	NC_008010 (Deinococcus geothermalis DSM 11300)	3e-28	42
1795) Caur_1833   ( YP_001635439.1 )	response regulator receiver	NC_010175 (Chloroflexus aurantiacus J-10-fl)	3e-28	41
1796) Chy400_1981   ( YP_002569712.1 )	winged helix family two component transcriptional regulator	NC_012032 (Chloroflexus sp. Y-400-fl)	3e-28	41
1797) mprA   ( YP_004522186.1 )	two component response transcriptional regulatory protein MprA	NC_015576 (Mycobacterium sp. JDM601)	3e-28	41
1798) Slin_0732   ( YP_003385594.1 )	transcriptional regulator	NC_013730 (Spirosoma linguale DSM 74)	3e-28	41
1799) arlR   ( YP_006015472.1 )	two-component response regulator ArlR	NC_017568 (Staphylococcus pseudintermedius ED99)	3e-28	41
1800) SPSINT_1128   ( YP_004149292.1 )	response regulator ArlR	NC_014925 (Staphylococcus pseudintermedius HKU10-03)	3e-28	41
1801) mprA   ( YP_004916982.1 )	two-component signal transduction system response regulator	NC_016112 (Methylomicrobium alcaliphilum 20Z)	4e-28	42
1802) syc0104_c   ( YP_170814.1 )	two-component response regulator for energy transfer from phycobilisomes to photosystems	NC_006576 (Synechococcus elongatus PCC6301)	5e-28	43
1803) M446_0275   ( YP_001767280.1 )	two component transcriptional regulator	NC_010511 (Methylobacterium sp. 4-46)	5e-28	41
1804) Kole_1429   ( YP_002941125.1 )	two component transcriptional regulator, winged helix family	NC_012785 (Kosmotoga olearia TBF 19.5.1)	1e-27	42
1805) RoseRS_2625   ( YP_001276951.1 )	two component transcriptional regulator	NC_009523 (Roseiflexus sp. RS-1)	5e-28	43
1806) Thimo_2146   ( YP_007244527.1 )	response regulator with CheY-like receiver domain and winged-helix DNA-binding domain	NC_019940 (Thioflavicoccus mobilis 8321)	5e-28	42
1807) Dgeo_2149   ( YP_605612.1 )	two component transcriptional regulator	NC_008025 (Deinococcus geothermalis DSM 11300)	6e-28	41
1808) Pfl01_3354   ( YP_349083.1 )	two component transcriptional regulator	NC_007492 (Pseudomonas fluorescens Pf0-1)	7e-28	43
1809) BN6_38910   ( YP_007038053.1 )	putative two-component system response regulator	NC_019673 (Saccharothrix espanaensis DSM 44229)	7e-28	42
1810) Daud_1897   ( YP_001718022.1 )	two component transcriptional regulator	NC_010424 (Candidatus Desulforudis audaxviator MP104C)	7e-28	41
1811) arlR   ( YP_006751931.1 )	response regulator ArlR	NC_018641 (Lactobacillus casei W56)	7e-28	41
1812) DGo_CA0101   ( YP_006259486.1 )	Two component transcriptional regulator, winged helix family	NC_017790 (Deinococcus gobiensis I-0)	8e-28	42
1813) LSA1384   ( YP_395994.1 )	two-component system response regulator	NC_007576 (Lactobacillus sakei 23K)	8e-28	42
1814) Cri9333_3966   ( YP_007144283.1 )	winged helix family two component transcriptional regulator	NC_019753 (Crinalium epipsammum PCC 9333)	8e-28	41
1815) Dalk_0317   ( YP_002429494.1 )	winged helix family two component transcriptional regulator	NC_011768 (Desulfatibacillum alkenivorans AK-01)	9e-28	41
1816) B737_8505   ( YP_008464833.1 )	two-component system response regulator	NC_022116 (Amycolatopsis mediterranei RB)	1e-27	43
1817) RAM_44315   ( YP_005536787.1 )	two-component system response regulator	NC_017186 (Amycolatopsis mediterranei S699)	1e-27	43
1818) AMES_8504   ( YP_006554981.1 )	two-component system response regulator	NC_018266 (Amycolatopsis mediterranei S699)	1e-27	43
1819) AMED_8635   ( YP_003770732.1 )	two-component system response regulator	NC_014318 (Amycolatopsis mediterranei U32)	1e-27	43
1820) copR   ( YP_005330229.1 )	Two component response regulator protein copR	NC_016943 (Blastococcus saxobsidens DD2)	1e-27	43
1821) Oscil6304_2780   ( YP_007086307.1 )	response regulator with CheY-like receiver domain and winged-helix DNA-binding domain	NC_019693 (Oscillatoria acuminata PCC 6304)	1e-27	43
1822) phoB-2   ( YP_002139751.1 )	winged-helix phosphate transcriptional response regulator	NC_011146 (Geobacter bemidjiensis Bem)	1e-27	42
1823) Apre_0086   ( YP_003151860.1 )	winged helix family two component transcriptional regulator	NC_013171 (Anaerococcus prevotii DSM 20548)	1e-27	41
1824) MLBr_02439   ( YP_002504210.1 )	two-component system response regulator	NC_011896 (Mycobacterium leprae Br4923)	1e-27	41
1825) ML2439   ( NP_302580.1 )	two-component system response regulator	NC_002677 (Mycobacterium leprae TN)	1e-27	41
1826) PSJM300_11470   ( YP_006524716.1 )	transcriptional regulatory protein TctD	NC_018177 (Pseudomonas stutzeri DSM 10701)	1e-27	41
1827) SRU_2830   ( YP_446921.1 )	response regulator receiver domain-containing protein	NC_007677 (Salinibacter ruber DSM 13855)	2e-27	44
1828) ompR   ( YP_003572919.1 )	response regulator receiver, transcriptional regulatory protein	NC_014032 (Salinibacter ruber M8)	2e-27	44
1829) Deide_01470   ( YP_002784710.1 )	response regulator CheY	NC_012526 (Deinococcus deserti VCD115)	2e-27	42
1830) Srot_1262   ( YP_003658563.1 )	transcriptional regulator	NC_014168 (Segniliparus rotundus DSM 44985)	2e-27	42
1831) Cal6303_4657   ( YP_007139529.1 )	winged helix family two component transcriptional regulator	NC_019751 (Calothrix sp. PCC 6303)	2e-27	41
1832) Chy400_3655   ( YP_002571349.1 )	winged helix family two component transcriptional regulator	NC_012032 (Chloroflexus sp. Y-400-fl)	2e-27	41
1833) EGYY_27730   ( YP_004712166.1 )	hypothetical protein	NC_015738 (Eggerthella sp. YY7918)	2e-27	41
1834) Mahau_0744   ( YP_004462766.1 )	winged helix family two component transcriptional regulator	NC_015520 (Mahella australiensis 50-1 BON)	2e-27	41
1835) Psed_0785   ( YP_004330895.1 )	winged helix family two component transcriptional regulator	NC_015312 (Pseudonocardia dioxanivorans CB1190)	2e-27	41
1836) tcrA   ( YP_006263292.1 )	response regulator mprA	NC_017803 (Actinoplanes sp. SE50/110)	2e-27	45
1837) GM21_1271   ( YP_003021089.1 )	transcriptional regulator	NC_012918 (Geobacter sp. M21)	2e-27	42
1838) MASS_1914   ( YP_008022380.1 )	putative transcriptional regulatory protein PrrA	NC_021282 (Mycobacterium abscessus 50594)	2e-27	41
1839) Dgeo_2318   ( YP_605779.1 )	two component transcriptional regulator	NC_008025 (Deinococcus geothermalis DSM 11300)	3e-27	43
1840) DGo_CA2430   ( YP_006261815.1 )	Two component transcriptional regulator, winged helix family	NC_017790 (Deinococcus gobiensis I-0)	3e-27	43
1841) Deima_0586   ( YP_004169910.1 )	winged helix family two component transcriptional regulator	NC_014958 (Deinococcus maricopensis DSM 21211)	3e-27	43
1842) LSEI_1679   ( YP_806894.1 )	DNA-binding response regulator	NC_008526 (Lactobacillus casei ATCC 334)	3e-27	42
1843) LCBD_1875   ( YP_005859912.1 )	DNA-binding response regulator YycF	NC_017474 (Lactobacillus casei BD-II)	3e-27	42
1844) rrp5   ( YP_001987835.1 )	Response regulator	NC_010999 (Lactobacillus casei BL23)	3e-27	42
1845) LC2W_1854   ( YP_005856770.1 )	DNA-binding response regulator YycF	NC_017473 (Lactobacillus casei LC2W)	3e-27	42
1846) LOCK919_1851   ( YP_008200362.1 )	DNA-binding heavy metal response regulator	NC_021721 (Lactobacillus casei LOCK919)	3e-27	42
1847) LCAZH_1669   ( YP_003788747.1 )	OmpR family DNA-binding response regulator	NC_014334 (Lactobacillus casei Zhang)	3e-27	42
1848) LBPG_00957   ( YP_008446940.1 )	two-component system response regulator	NC_022112 (Lactobacillus paracasei 8700:2)	3e-27	42
1849) LRHK_1698   ( YP_005873323.1 )	transcriptional regulatory, C terminal family protein	NC_017491 (Lactobacillus rhamnosus ATCC 8530)	3e-27	42
1850) rr2   ( YP_003171472.1 )	two-component response regulator	NC_013198 (Lactobacillus rhamnosus GG)	3e-27	42
1851) LRHM_1662   ( YP_005866154.1 )	two-component response regulator	NC_017482 (Lactobacillus rhamnosus GG)	3e-27	42
1852) rr2   ( YP_003174399.1 )	two-component response regulator	NC_013199 (Lactobacillus rhamnosus Lc 705)	3e-27	42
1853) LOCK900_1669   ( YP_008203291.1 )	DNA-binding heavy metal response regulator	NC_021723 (Lactobacillus rhamnosus LOCK900)	3e-27	42
1854) LOCK908_1763   ( YP_008206256.1 )	DNA-binding heavy metal response regulator	NC_021725 (Lactobacillus rhamnosus LOCK908)	3e-27	42
1855) Cyan10605_1525   ( YP_007161678.1 )	winged helix family two component transcriptional regulator	NC_019776 (Cyanobacterium aponinum PCC 10605)	3e-27	41
1856) kw2_0998   ( YP_008568641.1 )	two-component system response regulator	NC_022369 (Lactococcus lactis KW2)	3e-27	41
1857) MAB_1926   ( YP_001702663.1 )	Putative transcriptional regulatory protein PrrA	NC_010397 (Mycobacterium abscessus ATCC 19977)	3e-27	41
1858) Pmen_1459   ( YP_001186956.1 )	two component transcriptional regulator	NC_009439 (Pseudomonas mendocina ymp)	3e-27	41
1859) CCC13826_1969   ( YP_001467191.1 )	response regulator receiver domain-containing protein	NC_009802 (Campylobacter concisus 13826)	4e-27	41
1860) H681_14985   ( YP_007658405.1 )	two component transcriptional regulator	NC_020829 (Pseudomonas denitrificans ATCC 13867)	4e-27	41
1861) Psest_0204   ( YP_007238445.1 )	response regulator with CheY-like receiver domain and winged-helix DNA-binding domain	NC_019936 (Pseudomonas stutzeri RCH2)	4e-27	41
1862) Rxyl_0187   ( YP_642977.1 )	two component transcriptional regulator	NC_008148 (Rubrobacter xylanophilus DSM 9941)	5e-27	44
1863) Deipe_1602   ( YP_007180908.1 )	CheY-like receiver domain/winged-helix DNA-binding domain-containing response regulator	NC_019793 (Deinococcus peraridilitoris DSM 19664)	5e-27	43
1864) Eab7_2653   ( YP_006792346.1 )	two component transcriptional regulator, winged helix family	NC_018665 (Exiguobacterium antarcticum Eab7)	5e-27	42
1865) DND132_2000   ( YP_005168009.1 )	winged helix family two component transcriptional regulator	NC_016803 (Desulfovibrio desulfuricans ND132)	5e-27	41
1866) llrE   ( YP_006999439.1 )	two-component system regulator llrE	NC_019435 (Lactococcus lactis UC509.9)	5e-27	41
1867) tctD   ( YP_005940789.1 )	transcriptional regulatory protein TctD	NC_017532 (Pseudomonas stutzeri DSM 4166)	5e-27	41
1868) Clole_3064   ( YP_004309958.1 )	transcriptional regulator	NC_015275 (Clostridium lentocellum DSM 5427)	6e-27	42
1869) resD   ( YP_007520812.1 )	Transcriptional regulatory protein resD	NC_020504 (Streptomyces davawensis JCM 4913)	6e-27	42
1870) LKI_05725   ( YP_003621655.1 )	response regulator	NC_014136 (Leuconostoc kimchii IMSNU 11154)	6e-27	41
1871) LGMK_06415   ( YP_004705960.1 )	response regulator	NC_015734 (Leuconostoc sp. C2)	6e-27	41
1872) Thit_1470   ( YP_003477288.1 )	winged helix family two component transcriptional regulator	NC_013921 (Thermoanaerobacter italicus Ab9)	6e-27	41
1873) Tmath_1461   ( YP_003677183.1 )	winged helix family two component transcriptional regulator	NC_014209 (Thermoanaerobacter mathranii A3)	6e-27	41
1874) A605_11255   ( YP_007465613.1 )	transcriptional regulator	NC_020302 (Corynebacterium halotolerans YIM 70093)	7e-27	41
1875) tctD   ( YP_001174507.1 )	transcriptional regulatory protein TctD	NC_009434 (Pseudomonas stutzeri A1501)	7e-27	41
1876) A458_01080   ( YP_006455903.1 )	transcriptional regulatory protein TctD	NC_018028 (Pseudomonas stutzeri CCUG 29243)	7e-27	41
1877) Sros_2243   ( YP_003337968.1 )	response regulator receiver protein	NC_013595 (Streptosporangium roseum DSM 43021)	7e-27	41
1878) Dehly_1555   ( YP_003759156.1 )	winged helix family two component transcriptional regulator	NC_014314 (Dehalogenimonas lykanthroporepellens BL-DC-9)	8e-27	41
1879) llh_5755   ( YP_005875750.1 )	two-component system regulator	NC_017492 (Lactococcus lactis A76)	9e-27	41
1880) LACR_1090   ( YP_809047.1 )	DNA-binding response regulator	NC_008527 (Lactococcus lactis SK11)	9e-27	41
1881) tctD   ( YP_004716373.1 )	transcriptional regulatory protein TctD	NC_015740 (Pseudomonas stutzeri ATCC 17588)	9e-27	41
1882) CLDAP_04400   ( YP_005440377.1 )	putative OmpR family two-component response regulator	NC_017079 (Caldilinea aerophila DSM 14535)	1e-26	45
1883) RSPO_m00642   ( YP_006031816.1 )	response regulator in two-component regulatory system with cops, regulation of copper resistance	NC_017575 (Ralstonia solanacearum Po82)	1e-26	45
1884) RPSI07_mp1421   ( YP_003750366.1 )	DNA-binding response regulator in two-component system	NC_014310 (Ralstonia solanacearum PSI07)	1e-26	45
1885) HRM2_10430   ( YP_002602319.1 )	transcriptional regulatory protein	NC_012108 (Desulfobacterium autotrophicum HRM2)	1e-26	43
1886) SCAB_4041   ( YP_003486180.1 )	response regulator	NC_013929 (Streptomyces scabiei 87.22)	1e-26	42
1887) A3UG_20195   ( YP_006479451.1 )	DNA-binding transcriptional regulator BasR	NC_018079 (Enterobacter cloacae SDM)	1e-26	41
1888) Mfla_0489   ( YP_544600.1 )	two component transcriptional regulator	NC_007947 (Methylobacillus flagellatus KT)	1e-26	41
1889) Smed_0630   ( YP_001326321.1 )	two component transcriptional regulator	NC_009636 (Sinorhizobium medicae WSM419)	1e-26	41
1890) feuP   ( NP_385120.1 )	transcriptional regulator	NC_003047 (Sinorhizobium meliloti 1021)	1e-26	41
1891) feuP   ( YP_007574278.1 )	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain protein	NC_020528 (Sinorhizobium meliloti 2011)	1e-26	41
1892) SinmeB_0635   ( YP_005712815.1 )	winged helix family two component transcriptional regulator	NC_017322 (Sinorhizobium meliloti BL225C)	1e-26	41
1893) C770_GR4Chr1020   ( YP_007189581.1 )	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain protein	NC_019845 (Sinorhizobium meliloti GR4)	1e-26	41
1894) feuP   ( YP_005719217.1 )	probabable FeuP	NC_017325 (Sinorhizobium meliloti SM11)	1e-26	41
1895) TSC_c17350   ( YP_004202898.1 )	DNA-binding response regulator	NC_014974 (Thermus scotoductus SA-01)	1e-26	41
1896) feuP   ( YP_006839543.1 )	transcriptional regulator	NC_018700 (Sinorhizobium meliloti Rm41)	9e-27	41
1897) BSA_19840   ( YP_008085630.1 )	Phosphate regulon transcriptional regulatory protein PhoB (SphR)	NC_021485 (Streptococcus agalactiae 09mas018883)	2e-26	45
1898) MSA_20580   ( YP_008087793.1 )	Phosphate regulon transcriptional regulatory protein PhoB (SphR)	NC_021486 (Streptococcus agalactiae ILRI005)	2e-26	45
1899) SAIL_19920   ( YP_008118605.1 )	Phosphate regulon transcriptional regulatory protein PhoB (SphR)	NC_021507 (Streptococcus agalactiae ILRI112)	2e-26	45
1900) RSal33209_0687   ( YP_001623848.1 )	two-component response regulator	NC_010168 (Renibacterium salmoninarum ATCC 33209)	2e-26	43
1901) Sinac_0888   ( YP_007200988.1 )	response regulator with CheY-like receiver domain and winged-helix DNA-binding domain	NC_019892 (Singulisphaera acidiphila DSM 18658)	2e-26	42
1902) B841_10350   ( YP_008372029.1 )	transcriptional regulator	NC_021915 (Corynebacterium maris DSM 45190)	2e-26	41
1903) PACID_32180   ( YP_006982333.1 )	Transcriptional regulatory protein, C-terminal domain-containing protein	NC_019395 (Propionibacterium acidipropionici ATCC 4875)	2e-26	41
1904) MDS_1515   ( YP_004379298.1 )	two component transcriptional regulator	NC_015410 (Pseudomonas mendocina NK-01)	2e-26	41
1905) TEH_09050   ( YP_004886396.1 )	OmpR family two-component response regulator	NC_016052 (Tetragenococcus halophilus NBRC 12172)	2e-26	41
1906) F504_4906   ( YP_008238631.1 )	DNA-binding response regulator	NC_021745 (Ralstonia solanacearum FQY_4)	3e-26	45
1907) RSp1442   ( NP_523001.1 )	two-component response regulator transcription regulator protein	NC_003296 (Ralstonia solanacearum GMI1000)	3e-26	45
1908) phoB   ( NP_688948.1 )	phosphate regulon response regulator PhoB	NC_004116 (Streptococcus agalactiae 2603V/R)	3e-26	45
1909) SAK_1922   ( YP_330516.1 )	phosphate regulon transcriptinal regulatory protein PhoB	NC_007432 (Streptococcus agalactiae A909)	3e-26	45
1910) phoP   ( YP_006765021.1 )	phosphate regulon response regulator PhoB	NC_018646 (Streptococcus agalactiae GD201008-001)	3e-26	45
1911) gbs1948   ( NP_736381.1 )	hypothetical protein	NC_004368 (Streptococcus agalactiae NEM316)	3e-26	45
1912) AM1_F0113   ( YP_001522417.1 )	two-component transcriptional regulator	NC_009931 (Acaryochloris marina MBIC11017)	3e-26	41
1913) Bcell_4306   ( YP_004097264.1 )	winged helix family two component transcriptional regulator	NC_014829 (Bacillus cellulosilyticus DSM 2522)	3e-26	41
1914) Caur_3391   ( YP_001636965.1 )	response regulator receiver	NC_010175 (Chloroflexus aurantiacus J-10-fl)	3e-26	41
1915) PPSC2_c0695   ( YP_003944919.1 )	chemotaxis protein CheY	NC_014622 (Paenibacillus polymyxa SC2)	3e-26	41
1916) Rcas_0353   ( YP_001430503.1 )	two component transcriptional regulator	NC_009767 (Roseiflexus castenholzii DSM 13941)	3e-26	41
1917) basR   ( YP_007404246.1 )	DNA-binding response regulator in two-component regulatory system with BasS	NC_020211 (Serratia marcescens WW4)	3e-26	41
1918) WS0641   ( NP_906872.1 )	transcriptional activator protein COPR	NC_005090 (Wolinella succinogenes DSM 1740)	3e-26	41
1919) RTO_22740   ( YP_007787283.1 )	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	NC_021015 ([Ruminococcus] torques L2-14)	3e-26	43
1920) PFLU3126   ( YP_002872701.1 )	response regulator protein	NC_012660 (Pseudomonas fluorescens SBW25)	4e-26	43
1921) ompR   ( YP_001940850.1 )	DNA-binding response regulator, OmpR family (REC-wHTH domains)	NC_010794 (Methylacidiphilum infernorum V4)	4e-26	42
1922) RTCIAT899_CH05445   ( YP_007333043.1 )	two-component response regulator protein	NC_020059 (Rhizobium tropici CIAT 899)	4e-26	41
1923) Halsa_1753   ( YP_003995526.1 )	two component transcriptional regulator, winged helix family	NC_014654 (Halanaerobium hydrogeniformans sapolanicus)	5e-26	43
1924) Pput_3039   ( YP_001268351.1 )	two component transcriptional regulator	NC_009512 (Pseudomonas putida F1)	5e-26	42
1925) YSA_09730   ( YP_006389163.1 )	two component transcriptional regulator	NC_017986 (Pseudomonas putida ND6)	5e-26	42
1926) rcaC   ( YP_005188035.1 )	Protein rcaC	NC_016812 (Sinorhizobium fredii HH103)	5e-26	41
1927) GBS222_1623   ( YP_007969280.1 )	two-component response regulator (PhoB)	NC_021195 (Streptococcus agalactiae 2-22)	6e-26	45
1928) phoB   ( YP_006952000.1 )	phosphate regulon transcriptional regulatory protein phoB	NC_019048 (Streptococcus agalactiae SA20-06)	6e-26	45
1929) AM1_D0011   ( YP_001521822.1 )	two-component transcriptional regulator	NC_009929 (Acaryochloris marina MBIC11017)	6e-26	41
1930) NGR_c07760   ( YP_002825322.1 )	two-component response regulator protein	NC_012587 (Sinorhizobium fredii NGR234)	6e-26	41
1931) Pat9b_0497   ( YP_004114378.1 )	winged helix family two component transcriptional regulator	NC_014837 (Pantoea sp. At-9b)	7e-26	41
1932) PPS_2122   ( YP_004701563.1 )	two component transcriptional regulator	NC_015733 (Pseudomonas putida S16)	1e-25	43
1933) RUM_03870   ( YP_007828630.1 )	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	NC_021039 (Ruminococcus champanellensis 18P13)	1e-25	42
1934) phoP   ( YP_006919225.1 )	alkaline phosphatase synthesis transcriptional regulatory protein PhoP	NC_018870 (Thermacetogenium phaeum DSM 12270)	1e-25	42
1935) ABD1_22870   ( YP_007596833.1 )	two-component response regulator	NC_020547 (Acinetobacter baumannii D1279779)	1e-25	41
1936) Dacsa_1980   ( YP_007171984.1 )	response regulator with CheY-like receiver domain and winged-helix DNA-binding domain	NC_019780 (Dactylococcopsis salina PCC 8305)	1e-25	41
1937) Mpop_1663   ( YP_001924362.1 )	transcriptional regulator	NC_010725 (Methylobacterium populi BJ001)	1e-25	41
1938) Mycsm_05430   ( YP_007295026.1 )	response regulator with CheY-like receiver domain and winged-helix DNA-binding domain	NC_019966 (Mycobacterium smegmatis JS623)	1e-25	41
1939) NOCYR_4742   ( YP_005266130.1 )	putative two-component system response regulator	NC_016887 (Nocardia cyriacigeorgica GUH-2)	1e-25	41
1940) BF2241   ( YP_211864.1 )	two component system response regulator	NC_003228 (Bacteroides fragilis NCTC 9343)	7e-26	41
1941) BF2185   ( YP_099466.1 )	two-component system response regulator	NC_006347 (Bacteroides fragilis YCH46)	7e-26	41
1942) Thet_0940   ( YP_003903856.1 )	winged helix family two component transcriptional regulator	NC_014538 (Thermoanaerobacter sp. X513)	7e-26	41
1943) Teth514_1997   ( YP_001663605.1 )	two component transcriptional regulator	NC_010320 (Thermoanaerobacter sp. X514)	7e-26	41
1944) Sama_3303   ( YP_929175.1 )	response regulator receiver protein	NC_008700 (Shewanella amazonensis SB2B)	8e-26	42
1945) MycrhN_2665   ( YP_005000461.1 )	response regulator with CheY-like receiver domain and winged-helix DNA-binding domain	NC_016604 (Mycobacterium rhodesiae NBB3)	8e-26	41
1946) Thewi_1591   ( YP_004820278.1 )	winged helix family two component transcriptional regulator	NC_015958 (Thermoanaerobacter wiegelii Rt8.B1)	8e-26	41
1947) AOLE_05585   ( YP_003731387.1 )	transcriptional regulatory protein qseB	NC_014259 (Acinetobacter oleivorans DR1)	9e-26	41
1948) prrA   ( YP_006520753.1 )	transcriptional regulatory protein prrA	NC_018150 (Mycobacterium abscessus GO 06)	9e-26	41
1949) PputW619_3309   ( YP_001750163.1 )	two component transcriptional regulator	NC_010501 (Pseudomonas putida W619)	9e-26	41
1950) PSEEN2757   ( YP_608337.1 )	DNA-binding response regulator	NC_008027 (Pseudomonas entomophila L48)	1e-25	42
1951) O3I_016415   ( YP_006808218.1 )	two-component system response regulator	NC_018681 (Nocardia brasiliensis HUJEG-1)	2e-25	45
1952) A284_06560   ( YP_007385073.1 )	response regulator protein	NC_020164 (Staphylococcus warneri SG1)	2e-25	43
1953) Neut_1362   ( YP_747575.1 )	two component transcriptional regulator, winged helix family protein	NC_008344 (Nitrosomonas eutropha C91)	2e-25	42
1954) Sinac_0424   ( YP_007200558.1 )	response regulator with CheY-like receiver domain and winged-helix DNA-binding domain	NC_019892 (Singulisphaera acidiphila DSM 18658)	2e-25	42
1955) BF638R_2299   ( YP_005111354.1 )	putative two component system response regulator	NC_016776 (Bacteroides fragilis 638R)	2e-25	41
1956) DGI_0292   ( YP_008589392.1 )	putative two component transcriptional regulator, winged helix family	NC_022444 (Desulfovibrio gigas ATCC 19364)	2e-25	41
1957) mprA   ( YP_007562343.1 )	two-component response regulator MprA	NC_020520 (Ilumatobacter coccineum YM16-304)	2e-25	41
1958) qseB1   ( YP_006396097.1 )	transcriptional regulatory protein QseB	NC_018000 (Sinorhizobium fredii USDA 257)	2e-25	41
1959) TtJL18_0322   ( YP_006058019.1 )	response regulator with CheY-like receiver domain and winged-helix DNA-binding domain	NC_017587 (Thermus thermophilus JL-18)	2e-25	41
1960) ECENHK_15350   ( YP_006579535.1 )	transcriptional regulatory protein TctD	NC_018405 (Enterobacter cloacae ENHKU01)	3e-25	41
1961) Theba_2002   ( YP_006346888.1 )	response regulator with CheY-like receiver domain and winged-helix DNA-binding domain	NC_017934 (Mesotoga prima MesG1.Ag.4.2)	3e-25	42
1962) Acfer_0098   ( YP_003397822.1 )	two component transcriptional regulator, winged helix family	NC_013740 (Acidaminococcus fermentans DSM 20731)	3e-25	41
1963) Mycch_4391   ( YP_006454779.1 )	response regulator with CheY-like receiver domain and winged-helix DNA-binding domain	NC_018027 (Mycobacterium chubuense NBB4)	3e-25	41
1964) TREAZ_2302   ( YP_004525637.1 )	alkaline phosphatase synthesis transcriptional regulatory protein PhoP	NC_015577 (Treponema azotonutricium ZAS-9)	3e-25	41
1965) T1E_2717   ( YP_006533350.1 )	two component transcriptional regulator	NC_018220 (Pseudomonas putida DOT-T1E)	4e-25	42
1966) basR   ( YP_003294452.1 )	DNA-binding response regulator in two-component regulatory system with BasS	NC_013508 (Edwardsiella tarda EIB202)	4e-25	41
1967) ETAF_0349   ( YP_005697965.1 )	Transcriptional regulatory protein basR/pmrA	NC_017309 (Edwardsiella tarda FL6-60)	4e-25	41
1968) Mjls_4830   ( YP_001073086.1 )	two component transcriptional regulator	NC_009077 (Mycobacterium sp. JLS)	4e-25	41
1969) XOO1188   ( YP_199827.1 )	response regulator	NC_006834 (Xanthomonas oryzae KACC10331)	1e-24	41
1970) Amir_5468   ( YP_003103132.1 )	winged helix family two component transcriptional regulator	NC_013093 (Actinosynnema mirum DSM 43827)	5e-25	41
1971) prrA   ( YP_004722610.1 )	PrrA family transcriptional regulator	NC_015758 (Mycobacterium africanum GM041182)	5e-25	41
1972) prrA   ( NP_854584.1 )	two component response transcriptional regulatory protein PRRA	NC_002945 (Mycobacterium bovis AF2122/97)	5e-25	41
1973) prrA   ( YP_977049.1 )	two component response transcriptional regulatory protein prrA	NC_008769 (Mycobacterium bovis BCG Pasteur 1173P2)	5e-25	41
1974) K60_009640   ( YP_007430022.1 )	two component response transcriptional regulatory protein PRRA	NC_020245 (Mycobacterium bovis Korea 1168P)	5e-25	41
1975) prrA   ( YP_005170393.1 )	Two component response transcriptional regulatory protein	NC_016804 (Mycobacterium bovis Mexico)	5e-25	41
1976) prrA   ( YP_002643984.1 )	two component response transcriptional regulatory protein	NC_012207 (Mycobacterium bovis Tokyo 172)	5e-25	41
1977) prrA   ( YP_004744366.1 )	two component response transcriptional regulatory protein PRRA	NC_015848 (Mycobacterium canettii CIPT 140010059)	5e-25	41
1978) prrA   ( YP_007259615.1 )	Two component response transcriptional regulatory protein PrrA	NC_019950 (Mycobacterium canettii CIPT 140060008)	5e-25	41
1979) prrA   ( YP_007286782.1 )	Two component response transcriptional regulatory protein PrrA	NC_019965 (Mycobacterium canettii CIPT 140070008)	5e-25	41
1980) prrA   ( YP_007263620.1 )	Two component response transcriptional regulatory protein PrrA	NC_019951 (Mycobacterium canettii CIPT 140070010)	5e-25	41
1981) prrA   ( YP_007267584.1 )	Two component response transcriptional regulatory protein PrrA	NC_019952 (Mycobacterium canettii CIPT 140070017)	5e-25	41
1982) MT7199_0922   ( YP_007350660.1 )	TWO COMPONENT RESPONSE TRANSCRIPTIONAL REGULATORY protein PRRA	NC_020089 (Mycobacterium tuberculosis 7199-99)	5e-25	41
1983) J112_04870   ( YP_007853837.1 )	two component response transcriptionalregulatory protein	NC_021054 (Mycobacterium tuberculosis Beijing/NITR203)	5e-25	41
1984) J113_06320   ( YP_007960808.1 )	two component response transcriptionalregulatory protein	NC_021193 (Mycobacterium tuberculosis CAS/NITR204)	5e-25	41
1985) CCDC5079_0834   ( YP_005912257.1 )	two component response transcriptional regulatory protein PRRA	NC_017523 (Mycobacterium tuberculosis CCDC5079)	5e-25	41
1986) prrA   ( YP_008005785.1 )	two component system transcriptional regulator	NC_021251 (Mycobacterium tuberculosis CCDC5079)	5e-25	41
1987) CCDC5180_0826   ( YP_005908658.1 )	two component response transcriptional regulatory protein PRRA	NC_017522 (Mycobacterium tuberculosis CCDC5180)	5e-25	41
1988) MT0926   ( NP_335359.1 )	DNA-binding response regulator	NC_002755 (Mycobacterium tuberculosis CDC1551)	5e-25	41
1989) prrA   ( YP_005915982.1 )	two component response transcriptional regulatory protein PRRA	NC_017524 (Mycobacterium tuberculosis CTRI-2)	5e-25	41
1990) M943_04720   ( YP_008225002.1 )	transcriptional regulator	NC_021740 (Mycobacterium tuberculosis EAI5)	5e-25	41
1991) J114_04815   ( YP_007964776.1 )	two component response transcriptionalregulatory protein	NC_021194 (Mycobacterium tuberculosis EAI5/NITR206)	5e-25	41
1992) prrA   ( YP_007609482.1 )	two component response transcriptionalregulatory protein	NC_020559 (Mycobacterium tuberculosis Erdman (ATCC35801))	5e-25	41
1993) TBFG_10921   ( YP_001286866.1 )	two component system response transcriptional regulatory protein prrA	NC_009565 (Mycobacterium tuberculosis F11)	5e-25	41
1994) prrA   ( YP_001282204.1 )	two component response transcriptional regulatory protein PrrA	NC_009525 (Mycobacterium tuberculosis H37Ra)	5e-25	41
1995) prrA   ( NP_215418.1 )	Two component response transcriptional regulatory protein PrrA	NC_000962 (Mycobacterium tuberculosis H37Rv)	5e-25	41
1996) RVBD_0903c   ( YP_006514256.1 )	transcriptional regulatory protein prrA	NC_018143 (Mycobacterium tuberculosis H37Rv)	5e-25	41
1997) TBHG_00890   ( YP_002160964.1 )	two-component system transcriptional regulator PrrA	NC_022350 (Mycobacterium tuberculosis Haarlem)	5e-25	41
1998) TBMG_03086   ( YP_003033074.1 )	two component system transcriptional regulator prrA	NC_012943 (Mycobacterium tuberculosis KZN 1435)	5e-25	41
1999) TBSG_03106   ( YP_005101574.1 )	two component system transcriptional regulator prrA	NC_016768 (Mycobacterium tuberculosis KZN 4207)	5e-25	41
2000) TBXG_003065   ( YP_006474556.1 )	two component system transcriptional regulator prrA	NC_018078 (Mycobacterium tuberculosis KZN 605)	5e-25	41
2001) MRGA327_05660   ( YP_005359605.1 )	two component response transcriptional regulatory protein PRRA	NC_017026 (Mycobacterium tuberculosis RGTB327)	5e-25	41
2002) prrA   ( YP_005307242.1 )	hypothetical protein	NC_016934 (Mycobacterium tuberculosis UT205)	5e-25	41
2003) Rleg_1066   ( YP_002974900.1 )	transcriptional regulator	NC_012850 (Rhizobium leguminosarum WSM1325)	6e-25	43
2004) prrA   ( YP_006570248.1 )	Two component transcriptional regulator, winged helix family	NC_018289 (Mycobacterium smegmatis MC2 155)	6e-25	41
2005) prrA   ( YP_889895.1 )	DNA-binding response regulator PrrA	NC_008596 (Mycobacterium smegmatis MC2 155)	6e-25	41
2006) feuP   ( YP_001977539.1 )	two-component response regulator protein	NC_010994 (Rhizobium etli CIAT 652)	6e-25	41
2007) Glo7428_1879   ( YP_007127588.1 )	two component transcriptional regulator, winged helix family	NC_019745 (Gloeocapsa sp. PCC 7428)	7e-25	41
2008) Mkms_4535   ( YP_940516.1 )	two component transcriptional regulator	NC_008705 (Mycobacterium sp. KMS)	7e-25	41
2009) Mmcs_4448   ( YP_641608.1 )	two component transcriptional regulator	NC_008146 (Mycobacterium sp. MCS)	7e-25	41
2010) B479_11035   ( YP_007229048.1 )	two component transcriptional regulator	NC_019905 (Pseudomonas putida PC9)	8e-25	43
2011) qseB   ( YP_007552702.1 )	two-component transcriptional regulator	NC_020516 (Azoarcus sp. KH32C)	8e-25	42
2012) TC41_2079   ( YP_005518509.1 )	winged helix family two component transcriptional regulator	NC_017167 (Alicyclobacillus acidocaldarius Tc-4-1)	8e-25	41
2013) Cwoe_3240   ( YP_003395033.1 )	two component transcriptional regulator	NC_013739 (Conexibacter woesei DSM 14684)	8e-25	41
2014) Namu_1193   ( YP_003200589.1 )	winged helix family two component transcriptional regulator	NC_013235 (Nakamurella multipartita DSM 44233)	8e-25	41
2015) RPC_1830   ( YP_531708.1 )	two component transcriptional regulator	NC_007925 (Rhodopseudomonas palustris BisB18)	8e-25	41
2016) feuP   ( YP_767037.1 )	two-component response regulator transcriptional regulatory protein	NC_008380 (Rhizobium leguminosarum 3841)	9e-25	43
2017) pmrA   ( YP_001906290.1 )	DNA-binding transcriptional regulator BasR	NC_010694 (Erwinia tasmaniensis Et1/99)	9e-25	42
2018) Strvi_2323   ( YP_004812327.1 )	winged helix family two component transcriptional regulator	NC_015957 (Streptomyces violaceusniger Tu 4113)	9e-25	42
2019) RPSI07_mp1073   ( YP_003750029.1 )	putative two-component response regulator transcription regulator protein	NC_014310 (Ralstonia solanacearum PSI07)	1e-24	44
2020) Rleg2_0917   ( YP_002280437.1 )	transcriptional regulator	NC_011369 (Rhizobium leguminosarum WSM2304)	1e-24	43
2021) prrA   ( YP_904458.1 )	two component response transcriptional regulatory protein PrrA	NC_008611 (Mycobacterium ulcerans Agy99)	1e-24	42
2022) BN6_09420   ( YP_007035144.1 )	Two-component system, response regulator of the winged helix family	NC_019673 (Saccharothrix espanaensis DSM 44229)	1e-24	42
2023) Adeg_1028   ( YP_003239011.1 )	two component transcriptional regulator, winged helix family	NC_013385 (Ammonifex degensii KC4)	1e-24	41
2024) Calkro_1254   ( YP_004023934.1 )	two component transcriptional regulator, winged helix family	NC_014720 (Caldicellulosiruptor kronotskyensis 2002)	1e-24	41
2025) ECL_03539   ( YP_003614022.1 )	two-component system, OmpR family, response regulator TctD	NC_014121 (Enterobacter cloacae ATCC 13047)	1e-24	41
2026) ENC_39500   ( YP_007847274.1 )	transcriptional regulator	NC_021046 (Enterobacter cloacae NCTC 9394)	1e-24	41
2027) MASS_0940   ( YP_008021406.1 )	transcriptional regulatory protein PrrA	NC_021282 (Mycobacterium abscessus 50594)	1e-24	41
2028) MAB_0956c   ( YP_001701702.1 )	Probable transcriptional regulatory protein PrrA	NC_010397 (Mycobacterium abscessus ATCC 19977)	1e-24	41
2029) prrA   ( YP_006520279.1 )	transcriptional regulatory protein prrA	NC_018150 (Mycobacterium abscessus GO 06)	1e-24	41
2030) MAV_1022   ( YP_880280.1 )	PrrA family transcriptional regulator	NC_008595 (Mycobacterium avium 104)	1e-24	41
2031) MAP0834c   ( NP_959768.1 )	hypothetical protein	NC_002944 (Mycobacterium avium K-10)	1e-24	41
2032) MAP4_3026   ( YP_007972814.1 )	two component system transcriptional regulator prrA	NC_021200 (Mycobacterium avium MAP4)	1e-24	41
2033) prrA   ( YP_007370848.1 )	two-component response transcriptional regulatory protein PrrA	NC_020133 (Mycobacterium liflandii 128FXT)	1e-24	41
2034) prrA   ( YP_001852891.1 )	two-component response transcriptional regulatory protein PrrA	NC_010612 (Mycobacterium marinum M)	1e-24	41
2035) W7S_04405   ( YP_006304591.1 )	two-component response transcriptional regulatory protein PrrA	NC_017904 (Mycobacterium sp. MOTT36Y)	1e-24	41
2036) Noca_2062   ( YP_923258.1 )	two component transcriptional regulator	NC_008699 (Nocardioides sp. JS614)	1e-24	41
2037) RSPPHO_02082   ( YP_005417678.1 )	Two component transcriptional regulator, winged helix family	NC_017059 (Rhodospirillum photometricum DSM 122)	1e-24	41
2038) feuP   ( YP_468818.1 )	two-component response regulator protein	NC_007761 (Rhizobium etli CFN 42)	2e-24	43
2039) phoP   ( YP_008364053.1 )	virulence response regulator PhoP	NC_021905 (Rhizobium etli Mim1)	2e-24	43
2040) phoP   ( YP_002786669.1 )	response regulator OmpR	NC_012526 (Deinococcus deserti VCD115)	2e-24	42
2041) Athe_1456   ( YP_002573327.1 )	winged helix family two component transcriptional regulator	NC_012034 (Caldicellulosiruptor bescii DSM 6725)	2e-24	41
2042) Csac_2003   ( YP_001180779.1 )	winged helix family two component transcriptional regulator	NC_009437 (Caldicellulosiruptor saccharolyticus DSM 8903)	2e-24	41
2043) MLBr_02123   ( YP_002504032.1 )	two-component response regulator	NC_011896 (Mycobacterium leprae Br4923)	2e-24	41
2044) ML2123   ( NP_302402.1 )	two-component response regulator	NC_002677 (Mycobacterium leprae TN)	2e-24	41
2045) Mvan_5009   ( YP_955787.1 )	two component transcriptional regulator	NC_008726 (Mycobacterium vanbaalenii PYR-1)	2e-24	41
2046) PHZ_c2696   ( YP_002131534.1 )	response regulator(with CheY-like receiver domain and winged-helix DNA-binding domain)	NC_011144 (Phenylobacterium zucineum HLK1)	2e-24	41
2047) XOO_1083   ( YP_450112.1 )	hypothetical protein	NC_007705 (Xanthomonas oryzae MAFF 311018)	2e-24	41
2048) L483_11290   ( YP_008094045.1 )	transcriptional regulator	NC_021491 (Pseudomonas putida H8234)	2e-24	42
2049) Daci_2714   ( YP_001563737.1 )	two component transcriptional regulator	NC_010002 (Delftia acidovorans SPH-1)	2e-24	41
2050) Mflv_1744   ( YP_001133012.1 )	two component transcriptional regulator	NC_009338 (Mycobacterium gilvum PYR-GCK)	2e-24	41
2051) Mspyr1_11280   ( YP_004075646.1 )	response regulator with CheY-like receiver domain and winged-helix DNA-binding domain	NC_014814 (Mycobacterium gilvum Spyr1)	2e-24	41
2052) Varpa_0602   ( YP_004152934.1 )	winged helix family two component transcriptional regulator	NC_014931 (Variovorax paradoxus EPS)	3e-24	45
2053) Sgly_0261   ( YP_004264631.1 )	two component transcriptional regulator, winged helix family	NC_015172 (Syntrophobotulus glycolicus DSM 8271)	3e-24	42
2054) basR   ( NP_991969.1 )	DNA-binding transcriptional regulator BasR	NC_005810 (Yersinia pestis 91001)	3e-24	42
2055) A1122_08365   ( YP_005521344.1 )	DNA-binding transcriptional regulator BasR	NC_017168 (Yersinia pestis A1122)	3e-24	42
2056) basR   ( YP_001608275.1 )	DNA-binding transcriptional regulator BasR	NC_010159 (Yersinia pestis Angola)	3e-24	42
2057) YPA_0057   ( YP_649971.1 )	DNA-binding transcriptional regulator BasR	NC_008150 (Yersinia pestis Antiqua)	3e-24	42
2058) basR   ( YP_002348396.1 )	DNA-binding transcriptional regulator BasR	NC_003143 (Yersinia pestis CO92)	3e-24	42
2059) basR   ( YP_005506451.1 )	two-component system response regulator	NC_017154 (Yersinia pestis D106004)	3e-24	42
2060) basR   ( YP_005510148.1 )	two-component system response regulator	NC_017160 (Yersinia pestis D182038)	3e-24	42
2061) basR   ( YP_005622569.1 )	two-component system response regulator	NC_017265 (Yersinia pestis Harbin 35)	3e-24	42
2062) basR   ( NP_668014.1 )	DNA-binding transcriptional regulator BasR	NC_004088 (Yersinia pestis KIM)	3e-24	42
2063) YPN_3251   ( YP_649178.1 )	DNA-binding transcriptional regulator BasR	NC_008149 (Yersinia pestis Nepal516)	3e-24	42
2064) YPDSF_3556   ( YP_001164879.1 )	DNA-binding transcriptional regulator BasR	NC_009381 (Yersinia pestis Pestoides F)	3e-24	42
2065) basR   ( YP_003569424.1 )	two-component system response regulator	NC_014029 (Yersinia pestis Z176003)	3e-24	42
2066) basR   ( YP_001402561.1 )	BasR family transcriptional regulator	NC_009708 (Yersinia pseudotuberculosis IP 31758)	3e-24	42
2067) basR   ( YP_069012.1 )	DNA-binding transcriptional regulator BasR	NC_006155 (Yersinia pseudotuberculosis IP 32953)	3e-24	42
2068) YPTS_0499   ( YP_001870942.1 )	DNA-binding transcriptional regulator BasR	NC_010634 (Yersinia pseudotuberculosis PB1/+)	3e-24	42
2069) YPK_3741   ( YP_001722461.1 )	DNA-binding transcriptional regulator BasR	NC_010465 (Yersinia pseudotuberculosis YPIII)	3e-24	42
2070) Calhy_1280   ( YP_003992368.1 )	two component transcriptional regulator, winged helix family	NC_014652 (Caldicellulosiruptor hydrothermalis 108)	3e-24	41
2071) Deipr_1307   ( YP_004256073.1 )	two component transcriptional regulator, winged helix family	NC_015161 (Deinococcus proteolyticus MRP)	3e-24	41
2072) ECL_04562   ( YP_003615040.1 )	DNA-binding transcriptional regulator BasR	NC_014121 (Enterobacter cloacae ATCC 13047)	3e-24	41
2073) I917_06355   ( YP_007957056.1 )	two component response transcriptional regulatory protein PRRA	NC_021192 (Mycobacterium tuberculosis Haarlem/NITR202)	3e-24	41
2074) Tlie_0036   ( YP_004931879.1 )	two component transcriptional regulator, winged helix family	NC_016148 (Thermovirga lienii DSM 17291)	3e-24	41
2075) Calow_1235   ( YP_004002593.1 )	two component transcriptional regulator, winged helix family	NC_014657 (Caldicellulosiruptor owensensis OL)	4e-24	41
2076) pmrA   ( YP_004953833.1 )	transcriptional regulatory protein pmrA	NC_016514 (Enterobacter cloacae EcWSU1)	4e-24	41
2077) CYA_1033   ( YP_474491.1 )	DNA-binding response regulator	NC_007775 (Synechococcus sp. JA-3-3Ab)	5e-24	42
2078) Aaci_1970   ( YP_003185371.1 )	winged helix family two component transcriptional regulator	NC_013205 (Alicyclobacillus acidocaldarius DSM 446)	5e-24	41
2079) Bfae_20650   ( YP_003155462.1 )	response regulator with CheY-like receiver domain and winged-helix DNA-binding domain	NC_013172 (Brachybacterium faecium DSM 4810)	5e-24	41
2080) covR   ( YP_006034628.1 )	two-component system, response regulator CovR/CsrR	NC_017576 (Streptococcus gallolyticus ATCC 43143)	6e-24	43
2081) covR   ( YP_004288700.1 )	putative two-component response regulator, CovR	NC_015215 (Streptococcus gallolyticus ATCC BAA-2069)	6e-24	43
2082) covR   ( YP_003431239.1 )	two-component response regulator, CovR family	NC_013798 (Streptococcus gallolyticus UCN34)	6e-24	43
2083) Acid345_3099   ( YP_592174.1 )	two component transcriptional regulator	NC_008009 (Candidatus Koribacter versatilis Ellin345)	6e-24	42
2084) covR   ( YP_005204333.1 )	two-component response regulator, CovR family	NC_016826 (Streptococcus infantarius CJ18)	6e-24	42
2085) KE3_1686   ( YP_008356955.1 )	hypothetical protein	NC_021900 (Streptococcus lutetiensis 033)	6e-24	42
2086) prrA   ( YP_004522077.1 )	two-component response transcriptional regulatory protein PrrA	NC_015576 (Mycobacterium sp. JDM601)	6e-24	41
2087) SMA_1742   ( YP_005095341.1 )	Response regulator CsrR	NC_016749 (Streptococcus macedonicus ACA-DC 198)	7e-24	44
2088) Rxyl_3017   ( YP_645739.1 )	two component transcriptional regulator	NC_008148 (Rubrobacter xylanophilus DSM 9941)	7e-24	42
2089) MYSTI_00232   ( YP_007357275.1 )	DNA-binding response regulator	NC_020126 (Myxococcus stipitatus DSM 14675)	8e-24	41
2090) Plim_0003   ( YP_003628055.1 )	response regulator receiver	NC_014148 (Planctomyces limnophilus DSM 3776)	8e-24	41
2091) PP_2713   ( NP_744857.1 )	DNA-binding response regulator	NC_002947 (Pseudomonas putida KT2440)	1e-23	42
2092) ROP_20130   ( YP_002779205.1 )	OmpR family two-component response regulator	NC_012522 (Rhodococcus opacus B4)	1e-23	42
2093) FraEuI1c_4657   ( YP_004018519.1 )	transcriptional regulator	NC_014666 (Frankia sp. EuI1c)	1e-23	41
2094) phoB   ( YP_006890110.1 )	winged-helix phosphate transcriptional response regulator	NC_017454 (Geobacter sulfurreducens KN400)	1e-23	41
2095) phoB   ( NP_952155.1 )	winged-helix phosphate transcriptional response regulator	NC_002939 (Geobacter sulfurreducens PCA)	1e-23	41
2096) mtrA   ( YP_680467.1 )	DNA-binding response regulator	NC_008209 (Roseobacter denitrificans OCh 114)	1e-23	41
2097) RLO149_c039320   ( YP_004692797.1 )	response regulator receiver protein	NC_015730 (Roseobacter litoralis Och 149)	1e-23	41
2098) Swit_3577   ( YP_001264061.1 )	two component transcriptional regulator	NC_009511 (Sphingomonas wittichii RW1)	1e-23	41
2099) basR   ( YP_001004793.1 )	DNA-binding transcriptional regulator BasR	NC_008800 (Yersinia enterocolitica 8081)	1e-23	41
2100) Krad_1806   ( YP_001361556.1 )	winged helix family two component transcriptional regulator	NC_009664 (Kineococcus radiotolerans SRS30216)	2e-23	42
2101) PPUBIRD1_2959   ( YP_005930776.1 )	DNA-binding response regulator	NC_017530 (Pseudomonas putida BIRD-1)	2e-23	42
2102) YE105_C0444   ( YP_004296645.1 )	DNA-binding transcriptional regulator BasR	NC_015224 (Yersinia enterocolitica 105.5R(r))	2e-23	41
2103) Y11_36601   ( YP_006007159.1 )	transcriptional regulatory protein basR/pmrA	NC_017564 (Yersinia enterocolitica Y11)	2e-23	41
2104) NE1409   ( NP_841450.1 )	response regulator PhoP	NC_004757 (Nitrosomonas europaea ATCC 19718)	2e-23	42
2105) SPO3426   ( YP_168622.1 )	DNA-binding response regulator	NC_003911 (Ruegeria pomeroyi DSS-3)	2e-23	42
2106) ykoG   ( YP_004374379.1 )	two-component response regulator	NC_015391 (Carnobacterium sp. 17-4)	2e-23	41
2107) Sbal117_0362   ( YP_006035655.1 )	winged helix family two component transcriptional regulator	NC_017579 (Shewanella baltica OS117)	2e-23	41
2108) Sbal_0261   ( YP_001048664.1 )	two component transcriptional regulator	NC_009052 (Shewanella baltica OS155)	2e-23	41
2109) Tmz1t_1913   ( YP_002355560.1 )	winged helix family two component transcriptional regulator	NC_011662 (Thauera sp. MZ1T)	2e-23	41
2110) rrp5   ( YP_007986818.1 )	Response regulator	NC_021224 (Lactobacillus plantarum P-8)	3e-23	42
2111) Krad_2802   ( YP_001362536.1 )	winged helix family two component transcriptional regulator	NC_009664 (Kineococcus radiotolerans SRS30216)	3e-23	41
2112) RoseRS_0114   ( YP_001274504.1 )	two component transcriptional regulator	NC_009523 (Roseiflexus sp. RS-1)	3e-23	41
2113) Alvin_0025   ( YP_003442029.1 )	winged helix family two component transcriptional regulator	NC_013851 (Allochromatium vinosum DSM 180)	6e-23	41
2114) SCAB_10851   ( YP_003486825.1 )	two component system response regulator	NC_013929 (Streptomyces scabiei 87.22)	6e-23	41
2115) basR   ( YP_003520532.1 )	BasR	NC_013956 (Pantoea ananatis LMG 20103)	8e-23	41
2116) basR   ( YP_005195351.1 )	winged helix family two component transcriptional regulator	NC_016816 (Pantoea ananatis LMG 5342)	8e-23	41
2117) phoB   ( YP_006034757.1 )	OmpR family two component system phosphate regulon response regulator	NC_017576 (Streptococcus gallolyticus ATCC 43143)	9e-23	43
2118) phoB   ( YP_004288827.1 )	phosphate regulon response regulator PhoB	NC_015215 (Streptococcus gallolyticus ATCC BAA-2069)	9e-23	43
2119) phoB   ( YP_003431369.1 )	phosphate regulon response regulator PhoB	NC_013798 (Streptococcus gallolyticus UCN34)	9e-23	43
2120) M446_0057   ( YP_001767079.1 )	two component transcriptional regulator	NC_010511 (Methylobacterium sp. 4-46)	1e-22	43
2121) phoB   ( YP_007494944.1 )	Phosphate regulon transcriptional regulatory protein phoB	NC_020409 (Desulfovibrio piezophilus C1TLV30)	1e-22	41
2122) basR   ( YP_005934426.1 )	transcriptional regulatory protein BasR/PmrA BasR	NC_017531 (Pantoea ananatis AJ13355)	1e-22	41
2123) PAGR_g1859   ( YP_005992594.1 )	two component transcriptional regulator PmrA	NC_017554 (Pantoea ananatis PA13)	1e-22	41
2124) Noca_1559   ( YP_922760.1 )	response regulator receiver	NC_008699 (Nocardioides sp. JS614)	7e-23	43
2125) Desca_0357   ( YP_004496165.1 )	winged helix family two component transcriptional regulator	NC_015565 (Desulfotomaculum carboxydivorans CO-1-SRB)	1e-22	42
2126) SHJG_7991   ( YP_006249130.1 )	two-component system response regulator	NC_017765 (Streptomyces hygroscopicus 5008)	2e-22	41
2127) SHJGH_7753   ( YP_007696749.1 )	two-component system response regulator	NC_020895 (Streptomyces hygroscopicus TL01)	2e-22	41
2128) CC1_06520   ( YP_007768950.1 )	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	NC_021009 (Coprococcus catus GD/7)	2e-22	44
2129) Cphy_1620   ( YP_001558731.1 )	two component transcriptional regulator	NC_010001 (Clostridium phytofermentans ISDg)	2e-22	41
2130) TOL_1930   ( YP_007682582.1 )	two component transcriptional regulator, winged helix family	NC_020888 (Thalassolituus oleivorans MIL-1)	2e-22	42
2131) Bpet0096   ( YP_001628698.1 )	two-component response regulator	NC_010170 (Bordetella petrii DSM 12804)	3e-22	42
2132) Celf_0979   ( YP_004452503.1 )	winged helix family transcriptional regulator	NC_015514 (Cellulomonas fimi ATCC 484)	3e-22	42
2133) Trad_1590   ( YP_003705252.1 )	winged helix family two component transcriptional regulator	NC_014221 (Truepera radiovictrix DSM 17093)	3e-22	42
2134) mprA   ( YP_008461926.1 )	two-component system response regulator	NC_022116 (Amycolatopsis mediterranei RB)	3e-22	41
2135) RAM_28940   ( YP_005533722.1 )	two-component system response regulator	NC_017186 (Amycolatopsis mediterranei S699)	3e-22	41
2136) mprA   ( YP_006552075.1 )	two-component system response regulator	NC_018266 (Amycolatopsis mediterranei S699)	3e-22	41
2137) mprA   ( YP_003767821.1 )	two-component system response regulator	NC_014318 (Amycolatopsis mediterranei U32)	3e-22	41
2138) WKK_00875   ( YP_004725730.1 )	DNA-binding response regulator	NC_015759 (Weissella koreensis KACC 15510)	3e-22	41
2139) SACE_0101   ( YP_001102380.1 )	two component system response regulator	NC_009142 (Saccharopolyspora erythraea NRRL 2338)	5e-22	42
2140) sphR   ( YP_006372862.1 )	two component transcriptional regulator	NC_017956 (Tistrella mobilis KA081020-065)	7e-22	43
2141) Gura_1572   ( YP_001230341.1 )	two component transcriptional regulator	NC_009483 (Geobacter uraniireducens Rf4)	7e-22	41
2142) AORI_2168   ( YP_008011159.1 )	winged helix family two component transcriptional regulator	NC_021252 (Amycolatopsis orientalis HCCB10007)	8e-22	44
2143) Eab7_2741   ( YP_006792431.1 )	two component transcriptional regulator, winged helix family	NC_018665 (Exiguobacterium antarcticum Eab7)	1e-21	41
2144) PST_0906   ( YP_001171445.1 )	DNA-binding response regulator	NC_009434 (Pseudomonas stutzeri A1501)	1e-21	42
2145) phoP   ( YP_002522802.1 )	alkaline phosphatase synthesis transcriptional regulatory protein PhoP	NC_011959 (Thermomicrobium roseum DSM 5159)	1e-21	41
2146) PSTAB_0799   ( YP_004713169.1 )	DNA-binding response regulator	NC_015740 (Pseudomonas stutzeri ATCC 17588)	1e-21	42
2147) PSTAA_0851   ( YP_005937503.1 )	DNA-binding response regulator	NC_017532 (Pseudomonas stutzeri DSM 4166)	1e-21	42
2148) Exig_3031   ( YP_001815493.1 )	two component transcriptional regulator	NC_010556 (Exiguobacterium sibiricum 255-15)	2e-21	41
2149) GBP346_A0773   ( YP_002895497.1 )	DNA-binding response regulator	NC_012695 (Burkholderia pseudomallei MSHR346)	3e-21	41
2150) Eab7_2835   ( YP_006792524.1 )	two component transcriptional regulator, winged helix family protein	NC_018665 (Exiguobacterium antarcticum Eab7)	3e-21	41
2151) Mlg_2505   ( YP_743335.1 )	two component transcriptional regulator	NC_008340 (Alkalilimnicola ehrlichii MLHE-1)	3e-21	41
2152) Ferpe_0988   ( YP_005471217.1 )	response regulator with CheY-like receiver domain and winged-helix DNA-binding domain	NC_017095 (Fervidobacterium pennivorans DSM 9078)	3e-21	42
2153) qseB   ( YP_004848808.1 )	DNA-binding transcriptional regulator QseB	NC_016002 (Pseudogulbenkiania sp. NH8B)	6e-21	41
2154) Acear_0861   ( YP_003827460.1 )	two component transcriptional regulator, winged helix family	NC_014378 (Acetohalobium arabaticum DSM 5501)	7e-21	42
2155) CLH_1146   ( YP_001920540.1 )	alkaline phosphatase synthesis transcriptional regulatory proteinphoP	NC_010723 (Clostridium botulinum Alaska E43)	7e-21	42
2156) Lcho_2529   ( YP_001791559.1 )	two component transcriptional regulator	NC_010524 (Leptothrix cholodnii SP-6)	1e-20	41
2157) ETAC_01745   ( YP_007627842.1 )	DNA-binding transcriptional regulator BasR	NC_020796 (Edwardsiella tarda C07-087)	2e-20	42
2158) FRAAL1628   ( YP_711872.1 )	response regulator in two-component regulatory system	NC_008278 (Frankia alni ACN14a)	2e-20	41
2159) MCCL_1066   ( YP_002560469.1 )	response regulator ArlR	NC_011999 (Macrococcus caseolyticus JCSC5402)	2e-20	41
2160) phoB   ( YP_008010767.1 )	two-component system response regulator	NC_021252 (Amycolatopsis orientalis HCCB10007)	2e-20	42
2161) Rmar_0513   ( YP_003289803.1 )	winged helix family two component transcriptional regulator	NC_013501 (Rhodothermus marinus DSM 4252)	3e-20	41
2162) FraEuI1c_5905   ( YP_004019759.1 )	transcriptional regulator	NC_014666 (Frankia sp. EuI1c)	3e-20	41
2163) ML5_5763   ( YP_004085371.1 )	winged helix family two component transcriptional regulator	NC_014815 (Micromonospora sp. L5)	4e-20	41
2164) CLL_A1195   ( YP_001885393.1 )	alkaline phosphatase synthesis transcriptional regulatory proteinphoP	NC_010674 (Clostridium botulinum Eklund 17B)	5e-20	41
2165) Psed_5946   ( YP_004335921.1 )	winged helix family two component transcriptional regulator	NC_015312 (Pseudonocardia dioxanivorans CB1190)	7e-20	41
2166) Cwoe_1564   ( YP_003393367.1 )	two component transcriptional regulator	NC_013739 (Conexibacter woesei DSM 14684)	6e-20	41
2167) Anae109_0880   ( YP_001378073.1 )	two component transcriptional regulator	NC_009675 (Anaeromyxobacter sp. Fw109-5)	7e-20	43
2168) PputW619_3019   ( YP_001749880.1 )	two component transcriptional regulator	NC_010501 (Pseudomonas putida W619)	1e-19	42
2169) Deipr_1503   ( YP_004256258.1 )	two component transcriptional regulator, winged helix family	NC_015161 (Deinococcus proteolyticus MRP)	1e-19	43
2170) MXAN_3450   ( YP_631647.1 )	DNA-binding heavy metal response regulator	NC_008095 (Myxococcus xanthus DK 1622)	1e-19	41
2171) VAB18032_20120   ( YP_004405726.1 )	winged helix family two component transcriptional regulator	NC_015434 (Verrucosispora maris AB-18-032)	2e-19	45
2172) Micau_6165   ( YP_003839234.1 )	response regulator receiver	NC_014391 (Micromonospora aurantiaca ATCC 27029)	2e-19	41
2173) ML5_6127   ( YP_004085721.1 )	winged helix family two component transcriptional regulator	NC_014815 (Micromonospora sp. L5)	2e-19	41
2174) CKO_03752   ( YP_001455264.1 )	DNA-binding transcriptional regulator BasR	NC_009792 (Citrobacter koseri ATCC BAA-895)	2e-19	41
2175) FraEuI1c_4016   ( YP_004017890.1 )	transcriptional regulator	NC_014666 (Frankia sp. EuI1c)	4e-19	41
2176) M495_01715   ( YP_008228329.1 )	XRE family transcriptional regulator	NC_021741 (Serratia liquefaciens ATCC 27592)	4e-19	41
2177) Spro_0478   ( YP_001476714.1 )	DNA-binding transcriptional regulator BasR	NC_009832 (Serratia proteamaculans 568)	5e-19	42
2178) Kfla_6884   ( YP_003384672.1 )	winged helix family two component transcriptional regulator	NC_013729 (Kribbella flavida DSM 17836)	8e-19	42
2179) Exig_2929   ( YP_001815392.1 )	two component transcriptional regulator	NC_010556 (Exiguobacterium sibiricum 255-15)	9e-19	41
2180) SCE1572_12475   ( YP_008148938.1 )	chemotaxis protein CheY	NC_021658 (Sorangium cellulosum So0157-2)	9e-19	43
2181) sce2049   ( YP_001612688.1 )	two-component system response regulator	NC_010162 (Sorangium cellulosum So ce 56)	1e-18	42
2182) Amir_4935   ( YP_003102607.1 )	winged helix family two component transcriptional regulator	NC_013093 (Actinosynnema mirum DSM 43827)	1e-18	43
2183) Nhal_3047   ( YP_003528488.1 )	response regulator receiver	NC_013960 (Nitrosococcus halophilus Nc 4)	1e-18	41
2184) Sros_1333   ( YP_003337071.1 )	response regulator receiver protein	NC_013595 (Streptosporangium roseum DSM 43021)	1e-18	41
2185) SC3A4.01   ( NP_631137.1 )	two component response regulator protein	NC_003888 (Streptomyces coelicolor A3(2))	2e-18	41
2186) Intca_2929   ( YP_004100151.1 )	transcriptional regulator	NC_014830 (Intrasporangium calvum DSM 43043)	3e-18	41
2187) qseB2   ( YP_935174.1 )	DNA-binding response regulator	NC_008702 (Azoarcus sp. BH72)	3e-18	41
2188) Nwat_1227   ( YP_003760479.1 )	winged helix family two component transcriptional regulator	NC_014315 (Nitrosococcus watsonii C-113)	5e-18	41
2189) qseB1   ( YP_931768.1 )	transcriptional regulator	NC_008702 (Azoarcus sp. BH72)	8e-18	41
2190) Dgeo_0130   ( YP_603602.1 )	two component transcriptional regulator	NC_008025 (Deinococcus geothermalis DSM 11300)	9e-18	43
2191) CAP2UW1_3300   ( YP_003168494.1 )	winged helix family two component transcriptional regulator	NC_013194 (Candidatus Accumulibacter phosphatis UW-1)	1e-17	41
2192) ESA_03574   ( YP_001439621.1 )	DNA-binding transcriptional regulator BasR	NC_009778 (Cronobacter sakazakii ATCC BAA-894)	2e-17	41
2193) HCH_01849   ( YP_433112.1 )	response regulator	NC_007645 (Hahella chejuensis KCTC 2396)	5e-17	43
2194) SGR_6561   ( YP_001828073.1 )	two-component system response regulator	NC_010572 (Streptomyces griseus NBRC 13350)	7e-17	42
2195) phoB   ( YP_007600347.1 )	phosphate regulon response regulator	NC_020555 (Helicobacter cinaedi ATCC BAA-847)	7e-17	41
2196) HCN_0446   ( YP_006234853.1 )	phosphate regulon response regulator PhoB	NC_017761 (Helicobacter cinaedi PAGU611)	7e-17	41
2197) pmrA   ( YP_003208761.1 )	DNA-binding transcriptional regulator BasR	NC_013282 (Cronobacter turicensis z3032)	8e-17	41
2198) Deipe_0785   ( YP_007180126.1 )	CheY-like receiver domain/winged-helix DNA-binding domain-containing response regulator	NC_019793 (Deinococcus peraridilitoris DSM 19664)	8e-17	41
2199) CYA_1892   ( YP_475302.1 )	DNA-binding response regulator RpaA	NC_007775 (Synechococcus sp. JA-3-3Ab)	1e-16	41
2200) Desaci_3980   ( YP_006468178.1 )	response regulator with CheY-like receiver domain and winged-helix DNA-binding domain	NC_018068 (Desulfosporosinus acidiphilus SJ4)	1e-16	41
2201) CYB_0249   ( YP_476510.1 )	DNA-binding response regulator RpaA	NC_007776 (Synechococcus sp. JA-2-3B'a(2-13))	2e-16	41
2202) Smal_0473   ( YP_002026861.1 )	winged helix family two component transcriptional regulator	NC_011071 (Stenotrophomonas maltophilia R551-3)	2e-16	41
2203) BurJV3_0492   ( YP_004791052.1 )	two component winged helix family transcriptional regulator	NC_015947 (Stenotrophomonas maltophilia JV3)	3e-16	41
2204) rstA   ( YP_006183281.1 )	transcriptional regulator RstA	NC_017671 (Stenotrophomonas maltophilia D457)	3e-16	41
2205) Psefu_1281   ( YP_004473351.1 )	two component transcriptional regulator, winged helix family	NC_015556 (Pseudomonas fulva 12-X)	4e-16	42
2206) Trad_0881   ( YP_003704558.1 )	winged helix family two component transcriptional regulator	NC_014221 (Truepera radiovictrix DSM 17093)	5e-16	44
2207) XOC_3605   ( YP_005629863.1 )	two-component system response regulator protein	NC_017267 (Xanthomonas oryzae BLS256)	5e-16	42
2208) regX3   ( YP_062674.1 )	two-component system regulatory protein	NC_006087 (Leifsonia xyli CTCB07)	6e-16	41
2209) O159_06490   ( YP_008579401.1 )	two-component system regulatory protein	NC_022438 (Leifsonia xyli DSM 46306)	1e-15	41
2210) Hsero_2435   ( YP_003775842.1 )	transcription response regulator protein	NC_014323 (Herbaspirillum seropedicae SmR1)	2e-15	41
2211) KTR9_1781   ( YP_006668576.1 )	DNA-binding response regulator	NC_018581 (Gordonia sp. KTR9)	5e-15	41
2212) B565_0746   ( YP_004391398.1 )	putative transcriptional regulator	NC_015424 (Aeromonas veronii B565)	6e-15	42
2213) Caur_0876   ( YP_001634498.1 )	response regulator receiver	NC_010175 (Chloroflexus aurantiacus J-10-fl)	1e-14	41
2214) Chy400_0951   ( YP_002568700.1 )	winged helix family two component transcriptional regulator	NC_012032 (Chloroflexus sp. Y-400-fl)	1e-14	41
2215) BurJV3_3658   ( YP_004794197.1 )	two component winged helix family transcriptional regulator	NC_015947 (Stenotrophomonas maltophilia JV3)	4e-14	41