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Homologs of CDPW8_2184 gene of NC_016789_P2

protein-level

Hit (GenBank Accn)

Product

Source Genome

Eval.

Ident.(%)

1) CDPW8_2184
( YP_005143732.1 )

XRE family plasmid maintenance system antidote protein

NC_016789
(Corynebacterium diphtheriae PW8)

2e-159

100

2) FRAAL4987
( YP_715169.1 )

HTH-type transcriptional regulator

NC_008278
(Frankia alni ACN14a)

6e-87

3) MASS_1p0142
( YP_008017265.1 )

XRE family plasmid maintenance system antidote protein

NC_021278
(Mycobacterium abscessus 50594)

2e-85

4) Achl_1079
( YP_002487162.1 )

XRE family plasmid maintenance system antidote protein

NC_011886
(Arthrobacter chlorophenolicus A6)

7e-84

5) BLASA_1810
( YP_005328760.1 )

Plasmid maintenance system antidote protein, XRE family

NC_016943
(Blastococcus saxobsidens DD2)

1e-61

• Sequence Alignments

1) CDPW8_2184 in NC_016789


> NC_016789_P2|15|G15|376255273|YP_005143732.1|Corynebacterium_diphtheriae_PW8|+|16346..17440|-|CDPW8_2184|XRE 
family plasmid 
maintenance system antidote protein
Length=364

 Score =  555 bits (2095),  Expect = 2e-159, Method: Compositional matrix adjust.
 Identities = 364/364 (100%), Positives = 364/364 (100%), Gaps = 0/364 (0%)

Query  1    MNTPIATELFPAGEILADELDARGWTQTDFAEVLGRPAQFVSEIISGKKEITRESAAQIG  60
            MNTPIATELFPAGEILADELDARGWTQTDFAEVLGRPAQFVSEIISGKKEITRESAAQIG
Sbjct  1    MNTPIATELFPAGEILADELDARGWTQTDFAEVLGRPAQFVSEIISGKKEITRESAAQIG  60

Query  61   AALGTSAEFWLNLQDSYLLWKQSQDDRIQDNLNAVKTRAQLRELAPVSLLVKRGYITATD  120
            AALGTSAEFWLNLQDSYLLWKQSQDDRIQDNLNAVKTRAQLRELAPVSLLVKRGYITATD
Sbjct  61   AALGTSAEFWLNLQDSYLLWKQSQDDRIQDNLNAVKTRAQLRELAPVSLLVKRGYITATD  120

Query  121  VQSQVYEVLNLFGKKSFEDPLGISFAARRSNHEENVTVLQEAWAACVRATASTLDTAPYS  180
            VQSQVYEVLNLFGKKSFEDPLGISFAARRSNHEENVTVLQEAWAACVRATASTLDTAPYS
Sbjct  121  VQSQVYEVLNLFGKKSFEDPLGISFAARRSNHEENVTVLQEAWAACVRATASTLDTAPYS  180

Query  181  RKALEDLARTLSSRARDPQAFAEFQTLFAEAGVRLVYVEAFPGGKLDGCAMMVDGHPVIG  240
            RKALEDLARTLSSRARDPQAFAEFQTLFAEAGVRLVYVEAFPGGKLDGCAMMVDGHPVIG
Sbjct  181  RKALEDLARTLSSRARDPQAFAEFQTLFAEAGVRLVYVEAFPGGKLDGCAMMVDGHPVIG  240

Query  241  ISGRGKRLDKILFTILHETAHILLGHLVDNGEVIlddlsddsandeaeadQLVSELAISS  300
            ISGRGKRLDKILFTILHETAHILLGHLVDNGEVILDDLSDDSANDEAEADQLVSELAISS
Sbjct  241  ISGRGKRLDKILFTILHETAHILLGHLVDNGEVILDDLSDDSANDEAEADQLVSELAISS  300

Query  301  PLPAVPDRVHSSWIKEQASRLGVHPITLIGRLQKKGDLSWKTTLVRNAPTVIAQLESWKS  360
            PLPAVPDRVHSSWIKEQASRLGVHPITLIGRLQKKGDLSWKTTLVRNAPTVIAQLESWKS
Sbjct  301  PLPAVPDRVHSSWIKEQASRLGVHPITLIGRLQKKGDLSWKTTLVRNAPTVIAQLESWKS  360

Query  361  PIPS  364
            PIPS
Sbjct  361  PIPS  364

2) FRAAL4987 in NC_008278


> NC_016789_P2|15|G15|376255273|YP_005143732.1|Corynebacterium_diphtheriae_PW8|+|16346..17440|-|CDPW8_2184|XRE 
family plasmid 
maintenance system antidote protein
Length=364

 Score =  314 bits (1177),  Expect = 6e-87, Method: Compositional matrix adjust.
 Identities = 181/355 (51%), Positives = 265/355 (75%), Gaps = 2/355 (0%)

Query  5    PAEAFPVGEHLLEELDARGWSQAEFAEIIGRPAQVVSEIISGKKEITRESAAQISAALGT  64
            ++E FP GE L +ELDARGW+Q++FAE++GRPAQ VSEIISGKKEITRESAAQI+AALGT
Sbjct  6    ATELFPAGEILADELDARGWTQTDFAEVLGRPAQFVSEIISGKKEITRESAAQIGAALGT  65

Query  65   SPEYWLRYQDQYHLWRQEQDEGARRKLDDVRLRARLTELAPLAVLRKRGIVTATTLGGQA  124
            S+E+WL  QD Y LW+Q QD+  + +L+ V+ RA+L ELAP+++L KRG +TAT + +Q 
Sbjct  66   SAEFWLNLQDSYLLWKQSQDDRIQDNLNAVKTRAQLRELAPVSLLVKRGYITATDVQSQV  125

Query  125  DQLCRLLNIDHIGEQPKLPMAARRSNLGDQASSTQLTWLACVRRQAESQTVSVYSPIRLR  184
             ++  L+    + +   ++ AARRSN  ++ +  Q +W ACVR  A +   + YS   L 
Sbjct  126  YEVLNLFGKKSFEDPLGISFAARRSNHEENVTVLQEAWAACVRATASTLDTAPYSRKALE  185

Query  185  GLAERLSRDLQNPQAFADLPGRFADVGVRLVYVEAFPSSKIDGAAFSMGGTPVIGISGRG  244
            +LA  LS   ++PQAFA++   FA+ GVRLVYVEAFP++K+DG A  ++G PVIGISGRG
Sbjct  186  DLARTLSSRARDPQAFAEFQTLFAEAGVRLVYVEAFPGGKLDGCAMMVDGHPVIGISGRG  245

Query  245  QRLDKVLFTILHEVAHVVLDHITDT--VILDEENGNGRHQEKDANELAAKWVLPSPIPAI  302
            +RLDK+LFTILHE AH++L+H+ D   VILD+ ++++ ++E +A++L +   ++SP+PA+
Sbjct  246  KRLDKILFTILHETAHILLGHLVDNGEVILDDLSDDSANDEAEADQLVSELAISSPLPAV  305

Query  303  PERVGRTWLTAVAKKLGVHPIIIVGRLQNDGLLNWRSALAKNAPTVTSYLQDWEN  357
            P+RV  +W+   A +LGVHPI ++GRLQ+ G L+W+++L +NAPTV + L+ W +
Sbjct  306  PDRVHSSWIKEQASRLGVHPITLIGRLQKKGDLSWKTTLVRNAPTVIAQLESWKS  360

3) MASS_1p0142 in NC_021278


> NC_016789_P2|15|G15|376255273|YP_005143732.1|Corynebacterium_diphtheriae_PW8|+|16346..17440|-|CDPW8_2184|XRE 
family plasmid 
maintenance system antidote protein
Length=364

 Score =  309 bits (1158),  Expect = 2e-85, Method: Compositional matrix adjust.
 Identities = 186/361 (52%), Positives = 263/361 (73%), Gaps = 6/361 (1%)

Query  7    NDPLPIDQTPVGELLGAELEFRGWSQADFAAVIDRPTQFVSEIVTGKKEITRESAAQIGA  66
            N P++ +  P GE+L+ EL+ RGW+Q+DFA V++RP+QFVSEI++GKKEITRESAAQIGA
Sbjct  2    NTPIATELFPAGEILADELDARGWTQTDFAEVLGRPAQFVSEIISGKKEITRESAAQIGA  61

Query  67   ALGHSAEFWLRLQDQYFLARQAKNRTTQAKLDDVRRRARLNELAPIQLLQKRKILTGSTL  126
            ALG SAEFWL LQD Y+L +Q+++   Q +L+ V+ RA+L ELAP+ LL KR  +T++ +
Sbjct  62   ALGTSAEFWLNLQDSYLLWKQSQDDRIQDNLNAVKTRAQLRELAPVSLLVKRGYITATDV  121

Query  127  DELEAEVMNLFELTSieaepeiaaaaKRANPGEDITMLQQAWVACVRKQARKLPPDSEYS  186
            +    EV+NLF   S+E    I+ AA+R+N  E++T+LQ+AW ACVR  A  L   + YS
Sbjct  122  QSQVYEVLNLFGKKSFEDPLGISFAARRSNHEENVTVLQEAWAACVRATASTLDTAP-YS  180

Query  187  AEMLAKLASSLPRSVRTAEDFATLPDQLRDAGVRLVYVEALPGAKIDGCAMFVDGHPVIG  246
               L  LA +L+   R ++ FA +   + +AGVRLVYVEA+PG+K+DGCAM VDGHPVIG
Sbjct  181  RKALEDLARTLSSRARDPQAFAEFQTLFAEAGVRLVYVEAFPGGKLDGCAMMVDGHPVIG  240

Query  247  LSGRGKRLDKVLFTLLHEIAHILRGH-VDDGPIV-EDLDDSRAQESVREREANDGAGTWI  304
            +SGRGKRLDK+LFT+LHE AHIL GH VD+G ++ +DL D  A++   E EA++  +   
Sbjct  241  ISGRGKRLDKILFTILHETAHILLGHLVDNGEVILDDLSDDSAND---EAEADQLVSELA  297

Query  305  FPDGYPSVPSRINAPWVEQTATKLGLARIVLIGQLQKRGRLDWRTTLAKNAPSVSDVLPR  364
            ++   P+VP R++++W+ + A++LG+  I LIG+LQK+G L W+TTL +NAP+V   L  
Sbjct  298  ISSPLPAVPDRVHSSWIKEQASRLGVHPITLIGRLQKKGDLSWKTTLVRNAPTVIAQLES  357

Query  365  W  365
            W
Sbjct  358  W  358

4) Achl_1079 in NC_011886


> NC_016789_P2|15|G15|376255273|YP_005143732.1|Corynebacterium_diphtheriae_PW8|+|16346..17440|-|CDPW8_2184|XRE 
family plasmid 
maintenance system antidote protein
Length=364

 Score =  304 bits (1138),  Expect = 7e-84, Method: Compositional matrix adjust.
 Identities = 171/356 (49%), Positives = 256/356 (72%), Gaps = 3/356 (0%)

Query  6    AEAFPPGESLAEELETRHWSQSDFAQILGRPAQFVSEIIAGKKEITRESAAQIGAALDQP  65
            +E FP+GE LA+EL++R W+Q+DFA++LGRPAQFVSEII+GKKEITRESAAQIGAAL+ +
Sbjct  7    TELFPAGEILADELDARGWTQTDFAEVLGRPAQFVSEIISGKKEITRESAAQIGAALGTS  66

Query  66   PQYWLNLQNAYLLWSQAQNVENRKELNDVRRRARMNDLAPVALLRKRNLITGDTLAEQEA  125
            +++WLNLQ++YLLW Q+Q+   + +LN V+ RA++ +LAPV+LL KR  IT+  +  Q  
Sbjct  67   AEFWLNLQDSYLLWKQSQDDRIQDNLNAVKTRAQLRELAPVSLLVKRGYITATDVQSQVY  126

Query  126  QILELFQIRSLDETPKFLAAARRSNRNEEPTPTQKAWLACARKNAQRVKVAKYDKNKLRQ  185
            ++L+LF  +S+++   +  AARRSN++E+ T  Q AW AC R  A  +  A Y ++ L +
Sbjct  127  EVLNLFGKKSFEDPLGISFAARRSNHEENVTVLQEAWAACVRATASTLDTAPYSRKALED  186

Query  186  LASELSRIVAEPEEFQSLPERFSAAGVRLVYIEAFPGSKLNGASFLLDDDPEQPVIALSG  245
            LA  LS    +P+ F  +   F+ AGVRLVY+EAFPG+KL+G + ++D+   +PVI++SG
Sbjct  187  LARTLSSRARDPQAFAEFQTLFAEAGVRLVYVEAFPGGKLDGCAMMVDG---HPVIGISG  243

Query  246  RGKRLDGVLFTLLHEVAHIVLGHVSPDQLFIDEGAGQADEPQEQEADRQAGEWQIPGGLP  305
            RGKRLD +LFT+LHE AHI+LGH+  +   I ++ ++    +E EAD+  +E  I++ LP
Sbjct  244  RGKRLDKILFTILHETAHILLGHLVDNGEVILDDLSDDSANDEAEADQLVSELAISSPLP  303

Query  306  KPPNVIRKGWIQTAAQQAGVHPVVILGRLQIDKLLDWRTALAKGAPTVDSYLERWN  361
              P+ ++ +WI+  A + GVHP+ ++GRLQ    L W+T+L + APTV + LE W+
Sbjct  304  AVPDRVHSSWIKEQASRLGVHPITLIGRLQKKGDLSWKTTLVRNAPTVIAQLESWK  359

5) BLASA_1810 in NC_016943


> NC_016789_P2|15|G15|376255273|YP_005143732.1|Corynebacterium_diphtheriae_PW8|+|16346..17440|-|CDPW8_2184|XRE 
family plasmid 
maintenance system antidote protein
Length=364

 Score =  230 bits (857),  Expect = 1e-61, Method: Compositional matrix adjust.
 Identities = 169/349 (49%), Positives = 247/349 (71%), Gaps = 1/349 (0%)

Query  10   PVGRFLAEEIEAHGWTQAEFAAVLGRPVQFVSEIVNGKKEVTRESAAQIGAALGQTPEFW  69
            P G +LA+E++A+GWTQ++FA VLGRP QFVSEI++GKKE+TRESAAQIGAALG ++EFW
Sbjct  11   PAGEILADELDARGWTQTDFAEVLGRPAQFVSEIISGKKEITRESAAQIGAALGTSAEFW  70

Query  70   LSFQDEYLLSEQAKSTRTQQELSEVRRRARLNRLVPVATLRKRGVLVGKdldeleeevae  129
            L++QD YLL  Q++  R Q++L+ V+ RA+L  L PV+ L KRG + + D++    EV +
Sbjct  71   LNLQDSYLLWKQSQDDRIQDNLNAVKTRAQLRELAPVSLLVKRGYITATDVQSQVYEVLN  130

Query  130  lleldSIDDDPAFHIAARRSNHDEPVSSvqvawvacvrraarkrTGVKPFSKSKLERLAA  189
            L+   S++D  ++ +AARRSNH+E V+ +Q AW ACVR +A       P+S+  LE LA 
Sbjct  131  LFGKKSFEDPLGISFAARRSNHEENVTVLQEAWAACVRATASTLDTA-PYSRKALEDLAR  189

Query  190  QLPTLLSSPAGFRGLPERFADAGLVLVYVEALPGAKIDGCAFMLGKTPTIALSGRGKRLD  249
             L++    P +F  +   FA+AG+ LVYVEA+PG+K+DGCA M++  P I++SGRGKRLD
Sbjct  190  TLSSRARDPQAFAEFQTLFAEAGVRLVYVEAFPGGKLDGCAMMVDGHPVIGISGRGKRLD  249

Query  250  KVLWTLLHEVAHVILGHVSSEVLVetlddqdetddteneadRRAGAWllprplptppARI  309
            K+L T+LHE AH++LGH+  +  V   D  D++ + E EAD+  +   ++ PLP+ P R+
Sbjct  250  KILFTILHETAHILLGHLVDNGEVILDDLSDDSANDEAEADQLVSELAISSPLPAVPDRV  309

Query  310  GAGWVDSVASERRLAPIVIVGQLQQSQVLDWRTTLARNAPTVTGVLETW  358
             ++W+   AS   + PI ++G+LQ+   L W+TTL RNAPTV + LE+W
Sbjct  310  HSSWIKEQASRLGVHPITLIGRLQKKGDLSWKTTLVRNAPTVIAQLESW  358