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Homologs of SE0035 gene of NC_004461_R1

protein-level

Hit (GenBank Accn)

Product

Source Genome

Eval.

Ident.(%)

1) SE0035
( NP_763590.1 )

penicillin binding protein 4

NC_004461
(Staphylococcus epidermidis ATCC 12228)

6e-167

100

2) A284_00760
( YP_007383927.1 )

penicillin binding protein 4

NC_020164
(Staphylococcus warneri SG1)

5e-115

3) SLUG_01640
( YP_005759290.1 )

D-ala-D-ala-carboxypeptidase family protein

NC_017353
(Staphylococcus lugdunensis N920143)

7e-95

4) pbp4
( YP_002635533.1 )

penicillin binding protein 4

NC_012121
(Staphylococcus carnosus TM300)

4e-93

5) SH0303
( YP_252218.1 )

hypothetical protein

NC_007168
(Staphylococcus haemolyticus JCSC1435)

9e-81

6) pbp4
( YP_254169.1 )

penicillin binding protein 4

NC_007168
(Staphylococcus haemolyticus JCSC1435)

2e-57

• Sequence Alignments

1) SE0035 in NC_004461


> NC_004461_R1|13|G13|27466953|NP_763590.1|Staphylococcus_epidermidis_ATCC_12228|+|8397..9620|-|SE0035|penicillin 
binding protein 
4
Length=407

 Score =  580 bits (2190),  Expect = 6e-167, Method: Compositional matrix adjust.
 Identities = 380/380 (100%), Positives = 380/380 (100%), Gaps = 0/380 (0%)

Query  1    MLISLFCCSFFTNTTYALTPVEITNNSKAQLDEGLNPRGAVVTTTNGQILYKYHKDKKVD  60
            MLISLFCCSFFTNTTYALTPVEITNNSKAQLDEGLNPRGAVVTTTNGQILYKYHKDKKVD
Sbjct  1    MLISLFCCSFFTNTTYALTPVEITNNSKAQLDEGLNPRGAVVTTTNGQILYKYHKDKKVD  60

Query  61   PASTTKLMTMLVIYDDINHSKVSLKDKVKISERYQKMSQLPNLTTFPLKKGQTYTIEQLL  120
            PASTTKLMTMLVIYDDINHSKVSLKDKVKISERYQKMSQLPNLTTFPLKKGQTYTIEQLL
Sbjct  61   PASTTKLMTMLVIYDDINHSKVSLKDKVKISERYQKMSQLPNLTTFPLKKGQTYTIEQLL  120

Query  121  KQAALNSSNAATLVLAEHIDGDISKFTDRMNREAQLLGMNQTHFTNPSGAnnkiikpyep  180
            KQAALNSSNAATLVLAEHIDGDISKFTDRMNREAQLLGMNQTHFTNPSGANNKIIKPYEP
Sbjct  121  KQAALNSSNAATLVLAEHIDGDISKFTDRMNREAQLLGMNQTHFTNPSGANNKIIKPYEP  180

Query  181  kkykdeTSSYTTANDMAILTNHLLRKYPNILKMTQLETDTQYNQQLHNTNLSLPHQSLGM  240
            KKYKDETSSYTTANDMAILTNHLLRKYPNILKMTQLETDTQYNQQLHNTNLSLPHQSLGM
Sbjct  181  KKYKDETSSYTTANDMAILTNHLLRKYPNILKMTQLETDTQYNQQLHNTNLSLPHQSLGM  240

Query  241  KNVDGLKTGTSKEGYNLALTAKKDQLRVNTNLFNIQPYPSEKAKFARHKVANALTQNAFK  300
            KNVDGLKTGTSKEGYNLALTAKKDQLRVNTNLFNIQPYPSEKAKFARHKVANALTQNAFK
Sbjct  241  KNVDGLKTGTSKEGYNLALTAKKDQLRVNTNLFNIQPYPSEKAKFARHKVANALTQNAFK  300

Query  301  NYTYRKVISKGAHQIDGKTYNVKEDLYDVVPKDNSKYELKISEKNQLSVKYNRQFTKGEH  360
            NYTYRKVISKGAHQIDGKTYNVKEDLYDVVPKDNSKYELKISEKNQLSVKYNRQFTKGEH
Sbjct  301  NYTYRKVISKGAHQIDGKTYNVKEDLYDVVPKDNSKYELKISEKNQLSVKYNRQFTKGEH  360

Query  361  IPSVKVEPKFNFLSVLFQIT  380
            IPSVKVEPKFNFLSVLFQIT
Sbjct  361  IPSVKVEPKFNFLSVLFQIT  380

2) A284_00760 in NC_020164


> NC_004461_R1|13|G13|27466953|NP_763590.1|Staphylococcus_epidermidis_ATCC_12228|+|8397..9620|-|SE0035|penicillin 
binding protein 
4
Length=407

 Score =  407 bits (1533),  Expect = 5e-115, Method: Compositional matrix adjust.
 Identities = 234/378 (62%), Positives = 314/378 (84%), Gaps = 2/378 (0%)

Query  8    LMMIMMCLVLISPTVFAEQSPVDVAKQEHQDIDKQYNPKGMIVTTKDGQILYDYHGNTQV  67
            +++ + C  +++ T +A  +PV+++++   ++D   NP+G +VTT +GQILY YH + +V
Sbjct  1    MLISLFCCSFFTNTTYA-LTPVEITNNSKAQLDEGLNPRGAVVTTTNGQILYKYHKDKKV  59

Query  68   DPASTTKLMTMNLVYDDIKSGKIKMNDKVKITSRYEKMSELPNLTTFPLKEGTTVTINQL  127
            DPASTTKLMTM ++YDDI+ +K+ ++DKVKI+ RY+KMS+LPNLTTFPLK G T TI+QL
Sbjct  60   DPASTTKLMTMLVIYDDINHSKVSLKDKVKISERYQKMSQLPNLTTFPLKKGQTYTIEQL  119

Query  128  LKQAALESSNAATLVLAEHIDGSSSKFTDRMNQKAKDLGMKDTKFTNPSGANNKILKPYE  187
            LKQAAL+SSNAATLVLAEHIDG  SKFTDRMN+ A+ LGM++T FTNPSGANNKI+KPYE
Sbjct  120  LKQAALNSSNAATLVLAEHIDGDISKFTDRMNREAQLLGMNQTHFTNPSGANNKIIKPYE  179

Query  188  PKSYKDDTISHTTARDMSLLSNHILNAHPDVLKITKLSKDKQSNQELHNTNTSLPNEADG  247
            PK YKD+T S TTA DM++L+NH+L   P++LK+T+L  D Q NQ+LHNTN SLP+++ G
Sbjct  180  PKKYKDETSSYTTANDMAILTNHLLRKYPNILKMTQLETDTQYNQQLHNTNLSLPHQSLG  239

Query  248  MKDVDGLKTGTSDNGYNLELTAKRNHLRIVTGIFNVKPYPDEQAKHARQKLANALTEHVF  307
            MK+VDGLKTGTS +GYNL LTAK+++LR+ T +FN++PYP E+AK AR+K+ANALT++ F
Sbjct  240  MKNVDGLKTGTSKEGYNLALTAKKDQLRVNTNLFNIQPYPSEKAKFARHKVANALTQNAF  299

Query  308  KQYDYRKVISKGEHEIDGKKYEVKKDLYDLVPKDKSKYQLKVSEDNQLYVDYDRQFTKGH  367
            K+Y YRKVISKG H+IDGK Y+VK DLYD+VPKD+SKY+LK+SE NQL V Y+RQFTKG+
Sbjct  300  KNYTYRKVISKGAHQIDGKTYNVKEDLYDVVPKDNSKYELKISEKNQLSVKYNRQFTKGE  359

Query  368  QAPTVEVEPTTHW-GMIF  384
            + P+V VEP  +  +++F
Sbjct  360  HIPSVKVEPKFNFLSVLF  377

3) SLUG_01640 in NC_017353


> NC_004461_R1|13|G13|27466953|NP_763590.1|Staphylococcus_epidermidis_ATCC_12228|+|8397..9620|-|SE0035|penicillin 
binding protein 
4
Length=407

 Score =  340 bits (1278),  Expect = 7e-95, Method: Compositional matrix adjust.
 Identities = 203/368 (56%), Positives = 286/368 (78%), Gaps = 3/368 (0%)

Query  7    FVLLLCLCMMFSPLTTYAAKTPTQIAEAEKQHIAQHYNPKSMIVTTQQGQILYDYHQHDN  66
            ++ L+C C  F+  TTYA  TP +I++  K ++ +  NP++ +VTT +GQILY YH++ +
Sbjct  2    LISLFC-CSFFTN-TTYAL-TPVEITNNSKAQLDEGLNPRGAVVTTTNGQILYKYHKDKK  58

Query  67   VDPASITKLMTIYLVLDDIDKGKIKLTDEVKVSGRYAKMSRIPGLTTFPLIKGKTYTIKQ  126
            VDPAS TKLMT+ ++ DDI+ +K+ L D VK+S RY KMS++P LTTFPL KG+TYTI Q
Sbjct  59   VDPASTTKLMTMLVIYDDINHSKVSLKDKVKISERYQKMSQLPNLTTFPLKKGQTYTIEQ  118

Query  127  LLKQGALASSNAAMLVLAEHIDGNSSDFTHRMNRKAQALHMRHTHFNNPSGADNRLIKPF  186
            LLKQ+AL SSNAA LVLAEHIDG+ S FT+RMNR AQ L M +THF NPSGA+N++IKP+
Sbjct  119  LLKQAALNSSNAATLVLAEHIDGDISKFTDRMNREAQLLGMNQTHFTNPSGANNKIIKPY  178

Query  187  APSKYKQQHFSKTTAKDMAVLTQQLVKQHPKVLKITRLTSDKQHGHMLKNTNLSLPAQad  246
             P KYK++  S TTA+DMA+LT++L+++ P++LK+T+L +D Q  + L NTNLSLP Q+ 
Sbjct  179  EPKKYKDETSSYTTANDMAILTNHLLRKYPNILKMTQLETDTQYNQQLHNTNLSLPHQSL  238

Query  247  glagadglKTGTSNHGYNLALTAKQNNLRIHSVLFQVQPFADERAKHVRQQLSNIMVRRA  306
            G+   DGLKTGTS++GYNLALTAK+++LR+++ LF++QP++ E+AK  R++++N + + A
Sbjct  239  GMKNVDGLKTGTSKEGYNLALTAKKDQLRVNTNLFNIQPYPSEKAKFARHKVANALTQNA  298

Query  307  FKNYDYRKVLSKGQHRIQGKMYYVKKDLYDVVPKDHKGYQFKINHGKYVHLTYQRSFLPG  366
            FKNY YRKV+SKG H+I+GK Y VK DLYDVVPKD+  Y++KI++ + + + Y+R F  G
Sbjct  299  FKNYTYRKVISKGAHQIDGKTYNVKEDLYDVVPKDNSKYELKISEKNQLSVKYNRQFTKG  358

Query  367  THPPKVEV  374
             H P V V
Sbjct  359  EHIPSVKV  366

4) pbp4 in NC_012121


> NC_004461_R1|13|G13|27466953|NP_763590.1|Staphylococcus_epidermidis_ATCC_12228|+|8397..9620|-|SE0035|penicillin 
binding protein 
4
Length=407

 Score =  335 bits (1256),  Expect = 4e-93, Method: Compositional matrix adjust.
 Identities = 202/359 (57%), Positives = 282/359 (79%), Gaps = 2/359 (0%)

Query  18   FITPNTYAQQTPTEIAKQHHQPLNTQYNPKSAYVITQQGQILYDYHGNQSIDPASTTKLM  77
            F+T  TYA  TP EI+++    L+   NP++A V T +GQILY YH ++ +DPASTTKLM
Sbjct  10   FFTNTTYAL-TPVEITNNSKAQLDEGLNPRGAVVTTTNGQILYKYHKDKKVDPASTTKLM  68

Query  78   TVYLVLEAIEQGKIKPSDSVKITPSYEKLAQLPNLTTFPLKNKQTYTIDQLLKQAMLESS  137
            T+ ++ + I+++K+   D VKI+  Y+K++QLPNLTTFPLK+ QTYTI+QLLKQA L+SS
Sbjct  69   TMLVIYDDINHSKVSLKDKVKISERYQKMSQLPNLTTFPLKKGQTYTIEQLLKQAALNSS  128

Query  138  NAATLVLADKLSGDTSKFTDNMNAKAKELGMKHSHFTNPSGANNLLIQQFAPKAYKSETF  197
            NAATLVLA+ + GD SKFTD MN  A+ LGM+++HFTNPSGANN +I+ + PK YK ET 
Sbjct  129  NAATLVLAEHIDGDISKFTDRMNREAQLLGMNQTHFTNPSGANNKIIKPYEPKKYKDETS  188

Query  198  SHSTAQDMTILSKAIIKNYPKVLQYSSLKTDQQYGKKLTNTNLSLPGSQDALNGAQGLKT  257
            S +TA+DM+IL++ ++++YP++L+ + L TD QY ++L NTNLSLP    +++  +GLKT
Sbjct  189  SYTTANDMAILTNHLLRKYPNILKMTQLETDTQYNQQLHNTNLSLPHQSLGMKNVDGLKT  248

Query  258  GTSDNGYNLVLTTKRNNLRIDTTVMNVQPYPSETSKHARQKIANALTEDAYKHYEYRKVI  317
            GTS +GYNL LT+K+++LR++T + N+QPYPSE +K AR+K+ANALT++A+K+Y YRKVI
Sbjct  249  GTSKEGYNLALTAKKDQLRVNTNLFNIQPYPSEKAKFARHKVANALTQNAFKNYTYRKVI  308

Query  318  SKGEHELDGKTYDVKQDLYDVVPkdknk-yklkikndklQIDYPRQFLKGSHAPSVKVE  375
            SKG H++DGKTY+VK+DLYDVVPKD++K       +++L + Y RQF KG H PSVKVE
Sbjct  309  SKGAHQIDGKTYNVKEDLYDVVPKDNSKYELKISEKNQLSVKYNRQFTKGEHIPSVKVE  367

5) SH0303 in NC_007168


> NC_004461_R1|13|G13|27466953|NP_763590.1|Staphylococcus_epidermidis_ATCC_12228|+|8397..9620|-|SE0035|penicillin 
binding protein 
4
Length=407

 Score =  293 bits (1099),  Expect = 9e-81, Method: Compositional matrix adjust.
 Identities = 161/356 (46%), Positives = 268/356 (76%), Gaps = 1/356 (0%)

Query  28   SPVTIANKEKNSSISTKYQPSGVMLTTDQGQILYNYRGNNQVDPASMSKMMTLYLTYEAI  87
            +PV I+N+ K + +    +P G ++TT +GQILY+Y+ +++VDPAS +K+MT+ + Y+ I
Sbjct  19   TPVEITNNSK-AQLDEGLNPRGAVVTTTNGQILYKYHKDKKVDPASTTKLMTMLVIYDDI  77

Query  88   ENGKLKLNDKVKITNKYATMSNLPNLSSVSLKQGQTYTIEELIKQTTLASSNAAAMILGE  147
            +++K+ L+DKVKI+++Y  MS+LPNL++ +LK+GQTYTIE+L+KQ++L SSNAA+++L+E
Sbjct  78   NHSKVSLKDKVKISERYQKMSQLPNLTTFPLKKGQTYTIEQLLKQAALNSSNAATLVLAE  137

Query  148  KVSGDNNTFTNKMNQQAKSFNMTNTNFVNPAGAQNSLLDQYAPSKFKKQDFPKSTAKDMN  207
             + GD + FT++MN++A+ + M +T+F NP+GA+N ++  Y P K+K +  + +TA+DM 
Sbjct  138  HIDGDISKFTDRMNREAQLLGMNQTHFTNPSGANNKIIKPYEPKKYKDETSSYTTANDMA  197

Query  208  LLMQALIKKYPQILQISKLTRDTQRGNTFKSTNLSLKGQPLYLPGTDGLKTGTSNKGYNI  267
            +L + L++KYP+IL++++L  DTQ  + + +TNLSL  Q+L +   DGLKTGTS+ GYN+
Sbjct  198  ILTNHLLRKYPNILKMTQLETDTQYNQQLHNTNLSLPHQSLGMKNVDGLKTGTSKEGYNL  257

Query  268  ALTNKQDQLRLNETIMNVKPFGDVNAKYNRNRIGNQIIKQYRQKYEYKKVLTEGDHEIDG  327
            ALT K+DQLR+N  + N++P+   +AK+ R++++N + ++  ++Y Y+KV++ G H+IDG
Sbjct  258  ALTAKKDQLRVNTNLFNIQPYPSEKAKFARHKVANALTQNAFKNYTYRKVISKGAHQIDG  317

Query  328  NKYHVKKDLYDVVPKDKSKWHLAINSKGKVYVHYYRDFLPGSHYPRVAADKKWKWF  383
            + Y+VK DLYDVVPKD+SK +L I+ K ++ V Y R+F  G H P V  + K + +
Sbjct  318  KTYNVKEDLYDVVPKDNSKYELKISEKNQLSVKYNRQFTKGEHIPSVKVEPKFNFL  373

6) pbp4 in NC_007168


> NC_004461_R1|13|G13|27466953|NP_763590.1|Staphylococcus_epidermidis_ATCC_12228|+|8397..9620|-|SE0035|penicillin 
binding protein 
4
Length=407

 Score =  217 bits (806),  Expect = 2e-57, Method: Compositional matrix adjust.
 Identities = 144/358 (41%), Positives = 243/358 (68%), Gaps = 4/358 (1%)

Query  24   ASEYEPTPTEIARQYGYPNVTDAYQPEGSINVSQTGQILYDYQSNQKWYPASMTKLMTMY  83
             + Y  TP EI+ + + +++ ++ +P G++  +  GQILY Y+ ++K  PAS TKLMTM 
Sbjct  13   NTTYALTPVEITNN-SKAQLDEGLNPRGAVVTTTNGQILYKYHKDKKVDPASTTKLMTML  71

Query  84   LTLEAVNKGELSLNDKVHITDKHYRMSTLPELSNTKLYAGETYTISELLQITVsnssnaa  143
            +  + +N + +SL+DKV I+++  +MS LP+L+   L  G+TYTI +LL+ +  NSSNAA
Sbjct  72   VIYDDINHSKVSLKDKVKISERYQKMSQLPNLTTFPLKKGQTYTIEQLLKQAALNSSNAA  131

Query  144  aLILADEVSGNVNDFTDLMNKKAKALGMSNTHFVNPTGAENKQLKEFAPSKYKNQDNTTS  203
            +L+LA+++ G+++ FTD MN+ A+ LGM++THF NP+GA+NK +K + P KYK++ ++ +
Sbjct  132  TLVLAEHIDGDISKFTDRMNREAQLLGMNQTHFTNPSGANNKIIKPYEPKKYKDETSSYT  191

Query  204  TAKDFAILDHHVIKETPKILHFTKQLAPTQHGVTYYTFNHSLEGAKMSLLGTDGLKTGSS  263
            TA+D AIL +H+++  P+IL  T+  + TQ        N SL    +++   DGLKTG+S
Sbjct  192  TANDMAILTNHLLRKYPNILKMTQLETDTQYNQQLHNTNLSLPHQSLGMKNVDGLKTGTS  251

Query  264  DVADYNHTITTKRNNFRINQVIMGAGDYVNLGGEKQRNMMGNAMMNRSFDQYSYKKVLSK  323
               +YN ++T+K++++R+N  +     Y +  +   R+ ++NA+ + +F +Y+Y+KV+SK
Sbjct  252  K-EGYNLALTAKKDQLRVNTNLFNIQPYPSEKAKFARHKVANALTQNAFKNYTYRKVISK  310

Query  324  GTHKINGKKYYVKDNLYDVVPKGMNKKDYKFIVKDGSIHLDYNRQFLTKDDGPPKVEV  381
            G+H+I+GK Y VK++LYDVVPK+ +K + K I     + + YNRQF TK++  P V V
Sbjct  311  GAHQIDGKTYNVKEDLYDVVPKDNSKYELK-ISEKNQLSVKYNRQF-TKGEHIPSVKV  366