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Homologs of leuS gene of NC_007297_P1

1761

protein-level

Hit (GenBank Accn)

Product

Source Genome

Eval.

Ident.(%)

1) leuS
( NP_663938.1 )

leucyl-tRNA synthetase

NC_004070
(Streptococcus pyogenes MGAS315)

0.0

2) leuS
( NP_801399.1 )

leucyl-tRNA synthetase

NC_004606
(Streptococcus pyogenes SSI-1)

0.0

3) leuS
( YP_006932244.1 )

leucyl-tRNA synthetase

NC_018936
(Streptococcus pyogenes A20)

0.0

100

4) leuS
( YP_007586724.1 )

leucyl-tRNA synthetase

NC_020540
(Streptococcus pyogenes M1 476)

0.0

100

5) leuS
( YP_599750.1 )

leucyl-tRNA synthetase

NC_008023
(Streptococcus pyogenes MGAS2096)

0.0

100

6) leuS
( YP_281511.2 )

leucyl-tRNA synthetase

NC_007297
(Streptococcus pyogenes MGAS5005)

0.0

100

7) leuS
( YP_595881.1 )

leucyl-tRNA synthetase

NC_008021
(Streptococcus pyogenes MGAS9429)

0.0

100

8) leuS
( YP_597758.1 )

Leucyl-tRNA synthetase

NC_008022
(Streptococcus pyogenes MGAS10270)

0.0

9) leuS
( YP_006071350.1 )

leucyl-tRNA synthetase

NC_017596
(Streptococcus pyogenes Alab49)

0.0

10) leuS
( YP_001127737.1 )

leucyl-tRNA synthetase

NC_009332
(Streptococcus pyogenes Manfredo)

0.0

11) leuS
( YP_601647.1 )

leucyl-tRNA synthetase

NC_008024
(Streptococcus pyogenes MGAS10750)

0.0

12) leuS
( YP_279614.1 )

leucyl-tRNA synthetase

NC_007296
(Streptococcus pyogenes MGAS6180)

0.0

13) leuS
( YP_059511.1 )

leucyl-tRNA synthetase

NC_006086
(Streptococcus pyogenes MGAS10394)

0.0

14) leuS
( YP_002285196.1 )

leucyl-tRNA synthetase

NC_011375
(Streptococcus pyogenes NZ131)

0.0

15) leuS
( NP_268552.1 )

leucyl-tRNA synthetase

NC_002737
(Streptococcus pyogenes SF370)

0.0

16) leuS
( YP_003446969.1 )

leucyl-tRNA synthetase

NC_013853
(Streptococcus mitis B6)

0.0

17) leuS
( NP_606474.1 )

leucyl-tRNA synthetase

NC_003485
(Streptococcus pyogenes MGAS8232)

0.0

18) leuS
( YP_004727078.1 )

leucyl-tRNA synthetase

NC_015760
(Streptococcus salivarius CCHSS3)

0.0

19) leuS
( YP_005388244.1 )

leucyl-tRNA synthetase protein LeuS

NC_017040
(Streptococcus pyogenes MGAS15252)

0.0

20) leuS
( YP_005410951.1 )

leucyl-tRNA synthetase protein LeuS

NC_017053
(Streptococcus pyogenes MGAS1882)

0.0

21) leuS
( YP_001693783.1 )

leucyl-tRNA synthetase

NC_010380
(Streptococcus pneumoniae Hungary19A-6)

0.0

22) leuS
( NP_344793.1 )

leucyl-tRNA synthetase

NC_003028
(Streptococcus pneumoniae TIGR4)

0.0

23) leuS
( YP_006069400.1 )

leucyl-tRNA synthetase (Leucine--tRNA ligase) (LeuRS)

NC_017595
(Streptococcus salivarius JIM8777)

0.0

24) leuS
( NP_689043.1 )

leucyl-tRNA synthetase

NC_004116
(Streptococcus agalactiae 2603V/R)

0.0

25) leuS
( NP_736445.1 )

leucyl-tRNA synthetase

NC_004368
(Streptococcus agalactiae NEM316)

0.0

26) leuS
( YP_004622680.1 )

leucine--tRNA ligase

NC_015678
(Streptococcus parasanguinis ATCC 15912)

0.0

27) leuS
( YP_006061914.1 )

leucyl-tRNA synthetase

NC_017591
(Streptococcus pneumoniae INV104)

0.0

28) Ssal_01962
( YP_006069057.1 )

leucyl-tRNA synthetase

NC_017594
(Streptococcus salivarius 57.I)

0.0

29) BSA_20450
( YP_008085690.1 )

Leucyl-tRNA synthetase

NC_021485
(Streptococcus agalactiae 09mas018883)

0.0

30) leuS
( YP_330587.1 )

leucyl-tRNA synthetase

NC_007432
(Streptococcus agalactiae A909)

0.0

31) leuS
( YP_006765096.1 )

leucyl-tRNA synthetase

NC_018646
(Streptococcus agalactiae GD201008-001)

0.0

32) leuS
( YP_006952049.1 )

leucyl-tRNA synthetase

NC_019048
(Streptococcus agalactiae SA20-06)

0.0

33) leuS
( YP_004326734.1 )

leucyl-tRNA synthetase

NC_015291
(Streptococcus oralis Uo5)

0.0

34) MSA_21140
( YP_008087848.1 )

Leucyl-tRNA synthetase

NC_021486
(Streptococcus agalactiae ILRI005)

0.0

35) SAIL_20620
( YP_008118674.1 )

Leucyl-tRNA synthetase

NC_021507
(Streptococcus agalactiae ILRI112)

0.0

36) leuS
( YP_140649.1 )

leucyl-tRNA synthetase

NC_006449
(Streptococcus thermophilus CNRZ1066)

0.0

37) leuS
( YP_819776.1 )

leucyl-tRNA synthetase

NC_008532
(Streptococcus thermophilus LMD-9)

0.0

38) leuS
( YP_138760.1 )

leucyl-tRNA synthetase

NC_006448
(Streptococcus thermophilus LMG 18311)

0.0

39) Y1U_C0211
( YP_006339325.1 )

leucyl-tRNA synthetase

NC_017927
(Streptococcus thermophilus MN-ZLW-002)

0.0

40) STND_0220
( YP_006001795.1 )

leucyl-tRNA synthetase

NC_017563
(Streptococcus thermophilus ND03)

0.0

41) leuS
( YP_002036956.1 )

leucyl-tRNA synthetase

NC_011072
(Streptococcus pneumoniae G54)

0.0

42) leuS
( YP_004767696.1 )

leucyl-tRNA synthetase

NC_015875
(Streptococcus pseudopneumoniae IS7493)

0.0

43) leuS
( YP_007969315.1 )

Leucyl-tRNA synthetase

NC_021195
(Streptococcus agalactiae 2-22)

0.0

44) leuS
( YP_007924166.1 )

leucyl-tRNA ligase

NC_021175
(Streptococcus oligofermentans AS 1.3089)

0.0

45) leuS
( YP_006742512.1 )

leucyl-tRNA synthetase

NC_018630
(Streptococcus pneumoniae gamPNI0373)

0.0

46) leuS
( YP_002737525.1 )

leucyl-tRNA synthetase

NC_012467
(Streptococcus pneumoniae P1031)

0.0

47) leuS
( YP_006040020.1 )

leucyl-tRNA synthetase

NC_017581
(Streptococcus thermophilus JIM 8232)

0.0

48) leuS
( YP_002739616.1 )

leucyl-tRNA synthetase

NC_012468
(Streptococcus pneumoniae 70585)

0.0

49) leuS
( YP_003878503.1 )

leucyl-tRNA synthetase

NC_014498
(Streptococcus pneumoniae 670-6B)

0.0

50) MYY_0336
( YP_006252533.1 )

leucyl-tRNA synthetase

NC_017769
(Streptococcus pneumoniae ST556)

0.0

51) leuS
( YP_003724012.1 )

leucyl-tRNA synthetase

NC_014251
(Streptococcus pneumoniae TCH8431/19A)

0.0

52) leuS
( YP_006702152.1 )

leucyl-tRNA synthetase

NC_018594
(Streptococcus pneumoniae A45)

0.0

53) SPAP_0303
( YP_003875898.1 )

leucyl-tRNA synthetase

NC_014494
(Streptococcus pneumoniae AP200)

0.0

54) leuS
( YP_002510309.1 )

leucyl-tRNA synthetase

NC_011900
(Streptococcus pneumoniae ATCC 700669)

0.0

55) leuS
( YP_002735368.1 )

leucyl-tRNA synthetase

NC_012466
(Streptococcus pneumoniae JJA)

0.0

56) leuS
( YP_006063791.1 )

leucyl-tRNA synthetase

NC_017592
(Streptococcus pneumoniae OXC141)

0.0

57) leuS
( YP_007765602.1 )

leucyl-tRNA synthetase

NC_021006
(Streptococcus pneumoniae SNP034156)

0.0

58) leuS
( YP_007813954.1 )

leucyl-tRNA synthetase

NC_021028
(Streptococcus pneumoniae SNP034183)

0.0

59) leuS
( YP_007812128.1 )

leucyl-tRNA synthetase

NC_021026
(Streptococcus pneumoniae SNP994038)

0.0

60) leuS
( YP_007762802.1 )

leucyl-tRNA synthetase

NC_021005
(Streptococcus pneumoniae SNP994039)

0.0

61) leuS
( YP_002741802.1 )

leucyl-tRNA synthetase

NC_012469
(Streptococcus pneumoniae Taiwan19F-14)

0.0

62) leuS
( YP_815756.1 )

leucyl-tRNA synthetase

NC_008533
(Streptococcus pneumoniae D39)

0.0

63) leuS
( YP_006065586.1 )

leucyl-tRNA synthetase

NC_017593
(Streptococcus pneumoniae INV200)

0.0

64) leuS
( NP_357829.1 )

leucyl-tRNA synthetase

NC_003098
(Streptococcus pneumoniae R6)

0.0

65) L897_00975
( YP_008242489.1 )

leucyl-tRNA synthase

NC_021807
(Streptococcus pyogenes HSC5)

0.0

66) leuS
( YP_001834982.1 )

leucyl-tRNA synthetase

NC_010582
(Streptococcus pneumoniae CGSP14)

0.0

67) leuS
( YP_006309192.1 )

leucyl-tRNA synthetase

NC_017905
(Streptococcus parasanguinis FW213)

0.0

68) leuS
( YP_006014031.1 )

leucyl-tRNA synthetase

NC_017567
(Streptococcus dysgalactiae ATCC 12394)

0.0

69) leuS
( YP_002997710.1 )

leucyl-tRNA synthetase

NC_012891
(Streptococcus dysgalactiae GGS_124)

0.0

70) leuS
( YP_006860470.1 )

leucyl-tRNA synthetase

NC_018712
(Streptococcus dysgalactiae RE378)

0.0

71) leuS
( YP_006905649.1 )

leucyl-tRNA synthetase

NC_019042
(Streptococcus dysgalactiae AC-2713)

0.0

72) K710_2041
( YP_008057720.1 )

LeuS

NC_021314
(Streptococcus iniae SF1)

0.0

73) leuS
( YP_006083568.1 )

leucyl-tRNA synthetase

NC_017621
(Streptococcus suis D12)

0.0

74) leuS
( YP_002743705.1 )

leucyl-tRNA synthetase

NC_012470
(Streptococcus equi H70)

0.0

75) leuS
( YP_004479866.1 )

leucyl-tRNA synthetase

NC_015558
(Streptococcus parauberis KCTC 11537)

0.0

76) leuS
( YP_001034296.1 )

leucyl-tRNA synthetase

NC_009009
(Streptococcus sanguinis SK36)

0.0

77) leuS
( YP_001201642.1 )

leucyl-tRNA synthetase

NC_009443
(Streptococcus suis 98HAH33)

0.0

78) leuS
( YP_003029622.1 )

leucyl-tRNA synthetase

NC_012926
(Streptococcus suis BM407)

0.0

79) SSGZ1_1889
( YP_006075287.1 )

leucyl-tRNA synthetase

NC_017617
(Streptococcus suis GZ1)

0.0

80) leuS
( YP_006077353.1 )

leucyl-tRNA synthetase

NC_017618
(Streptococcus suis JS14)

0.0

81) leuS
( YP_003027690.1 )

leucyl-tRNA synthetase

NC_012925
(Streptococcus suis P1/7)

0.0

82) leuS
( YP_006650703.1 )

leucyl-tRNA ligase

NC_018526
(Streptococcus suis S735)

0.0

83) NJAUSS_1917
( YP_007571856.1 )

leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

NC_020526
(Streptococcus suis SC070731)

0.0

84) leuS
( YP_003025864.1 )

leucyl-tRNA synthetase

NC_012924
(Streptococcus suis SC84)

0.0

85) leuS
( YP_006079435.1 )

leucyl-tRNA synthetase

NC_017619
(Streptococcus suis SS12)

0.0

86) KE3_0089
( YP_008355488.1 )

leucyl-tRNA synthetase

NC_021900
(Streptococcus lutetiensis 033)

0.0

87) leuS
( YP_006081502.1 )

leucyl-tRNA synthetase

NC_017620
(Streptococcus suis D9)

0.0

88) leuS
( YP_001199447.1 )

leucyl-tRNA synthetase

NC_009442
(Streptococcus suis 05ZYH33)

0.0

89) leuS
( YP_002745647.1 )

leucyl-tRNA synthetase

NC_012471
(Streptococcus equi 4047)

0.0

90) leuS
( YP_001451053.1 )

leucyl-tRNA synthetase

NC_009785
(Streptococcus gordonii Challis)

0.0

91) leuS
( YP_006085554.1 )

leucyl-tRNA synthetase

NC_017622
(Streptococcus suis A7)

0.0

92) leuS
( YP_004402519.1 )

leucyl-tRNA synthetase

NC_015433
(Streptococcus suis ST3)

0.0

93) larS
( YP_006042072.1 )

leucyl-tRNA synthetase

NC_017582
(Streptococcus equi ATCC 35246)

0.0

94) leuS
( YP_002122557.1 )

leucyl-tRNA synthetase

NC_011134
(Streptococcus equi MGCS10565)

0.0

95) leuS
( YP_006359837.1 )

leucyl-tRNA synthetase

NC_017950
(Streptococcus suis ST1)

0.0

96) leuS
( YP_002563002.1 )

leucyl-tRNA synthetase

NC_012004
(Streptococcus uberis 0140J)

0.0

97) leuS
( YP_006032991.1 )

leucyl-tRNA synthetase

NC_017576
(Streptococcus gallolyticus ATCC 43143)

0.0

98) leuS
( YP_004287070.1 )

leucyl-tRNA synthetase

NC_015215
(Streptococcus gallolyticus ATCC BAA-2069)

0.0

99) leuS
( YP_003429578.1 )

leucyl-tRNA synthetase

NC_013798
(Streptococcus gallolyticus UCN34)

0.0

100) leuS
( YP_003484127.1 )

leucyl-tRNA synthetase

NC_013928
(Streptococcus mutans NN2025)

0.0

101) leuS
( YP_005093882.1 )

leucyl-tRNA synthetase

NC_016749
(Streptococcus macedonicus ACA-DC 198)

0.0

102) leuS
( YP_006491012.1 )

leucyl-tRNA ligase

NC_018089
(Streptococcus mutans GS-5)

0.0

103) leuS
( YP_006250511.1 )

putative leucyl-tRNA synthetase

NC_017768
(Streptococcus mutans LJ23)

0.0

104) syl
( NP_722247.1 )

leucyl-tRNA synthetase

NC_004350
(Streptococcus mutans UA159)

0.0

105) leuS
( YP_004558352.1 )

leucyl-tRNA synthetase

NC_015600
(Streptococcus pasteurianus ATCC 43144)

0.0

106) leuS
( YP_007976237.1 )

Leucyl-tRNA synthetase

NC_021213
(Streptococcus suis TL13)

0.0

107) leuS
( YP_008497750.1 )

leucyl-tRNA synthetase

NC_022237
(Streptococcus intermedius C270)

0.0

108) leuS
( YP_008508714.1 )

leucyl-tRNA synthetase

NC_022244
(Streptococcus anginosus C1051)

0.0

109) leuS
( YP_008499561.1 )

leucyl-tRNA synthetase

NC_022238
(Streptococcus constellatus C1050)

0.0

110) leuS
( YP_008495985.1 )

leucyl-tRNA synthetase

NC_022236
(Streptococcus constellatus C232)

0.0

111) leuS
( YP_008511746.1 )

leucyl-tRNA synthetase

NC_022245
(Streptococcus constellatus C818)

0.0

112) leuS
( YP_008500048.1 )

leucyl-tRNA synthetase

NC_022239
(Streptococcus anginosus C238)

0.0

113) leuS
( YP_006470305.1 )

leucyl-tRNA synthetase

NC_018073
(Streptococcus intermedius JTH08)

0.0

114) leuS
( YP_008513527.1 )

leucyl-tRNA synthetase

NC_022246
(Streptococcus intermedius B196)

0.0

115) leuS
( YP_005868172.1 )

leucyl-tRNA synthetase

NC_017486
(Lactococcus lactis CV56)

0.0

116) leuS
( NP_266972.1 )

leucyl-tRNA synthetase

NC_002662
(Lactococcus lactis IL1403)

0.0

117) leuS
( YP_007508080.1 )

leucyl-tRNA synthetase

NC_020450
(Lactococcus lactis IO-1)

0.0

118) leuS
( YP_003353290.1 )

leucyl-tRNA synthetase

NC_013656
(Lactococcus lactis KF147)

0.0

119) leuS
( YP_001033014.1 )

leucyl-tRNA synthetase

NC_009004
(Lactococcus lactis MG1363)

0.0

120) leuS
( YP_006357147.1 )

leucyl-tRNA synthetase

NC_017949
(Lactococcus lactis NZ9000)

0.0

121) LCGT_0691
( YP_004778868.1 )

leucyl-tRNA synthetase

NC_015930
(Lactococcus garvieae ATCC 49156)

0.0

122) LCGL_0711
( YP_005870455.1 )

leucyl-tRNA synthetase

NC_017490
(Lactococcus garvieae Lg2)

0.0

123) llh_8685
( YP_005876336.1 )

leucyl-tRNA synthetase

NC_017492
(Lactococcus lactis A76)

0.0

124) leuS
( YP_808847.1 )

leucyl-tRNA synthetase

NC_008527
(Lactococcus lactis SK11)

0.0

125) leuS
( YP_006999251.1 )

leucyl-tRNA synthetase

NC_019435
(Lactococcus lactis UC509.9)

0.0

126) leuS
( YP_008568410.1 )

leucyl-tRNA synthetase LeuS

NC_022369
(Lactococcus lactis KW2)

0.0

127) ECBG_02263
( YP_007754123.1 )

leucyl-tRNA synthetase

NC_020995
(Enterococcus casseliflavus EC20)

0.0

128) leuS
( YP_004374277.1 )

leucine--tRNA ligase

NC_015391
(Carnobacterium sp. 17-4)

0.0

129) leuS
( NP_814544.1 )

leucyl-tRNA synthetase

NC_004668
(Enterococcus faecalis V583)

0.0

130) leuS
( YP_007152432.1 )

leucyl-tRNA synthetase

NC_019770
(Enterococcus faecalis Symbioflor 1)

0.0

131) leuS
( NP_471105.1 )

leucyl-tRNA synthetase

NC_003212
(Listeria innocua Clip11262)

0.0

132) leuS
( YP_008396189.1 )

leucyl-tRNA synthetase

NC_021994
(Enterococcus faecium AUS0085)

0.0

133) leuS
( YP_006377136.1 )

leucyl-tRNA synthetase

NC_017960
(Enterococcus faecium DO)

0.0

134) M7W_2542
( YP_007395198.1 )

Leucyl-tRNA synthetase

NC_020207
(Enterococcus faecium NRRL B-2354)

0.0

135) ENT_22930
( YP_007808483.1 )

leucyl-tRNA synthetase

NC_021023
(Enterococcus sp. 7L76)

0.0

136) MPD5_0393
( YP_005319164.1 )

leucyl-tRNA synthetase

NC_016938
(Melissococcus plutonius DAT561)

0.0

137) leuS
( YP_005355783.1 )

leucyl-tRNA synthetase

NC_017022
(Enterococcus faecium Aus0004)

0.0

138) EFD32_0611
( YP_006536978.1 )

leucyl-tRNA synthetase

NC_018221
(Enterococcus faecalis D32)

0.0

139) leuS
( YP_005707591.1 )

leucyl-tRNA synthetase

NC_017316
(Enterococcus faecalis OG1RF)

0.0

140) leuS
( YP_001487887.1 )

leucyl-tRNA synthetase

NC_009848
(Bacillus pumilus SAFR-032)

0.0

141) leuS
( YP_006461685.1 )

leucyl-tRNA synthetase

NC_018065
(Solibacillus silvestris StLB046)

0.0

142) MPTP_1662
( YP_004456898.1 )

leucyl-tRNA synthetase

NC_015516
(Melissococcus plutonius ATCC 35311)

0.0

143) leuS
( YP_001126832.1 )

leucyl-tRNA synthetase

NC_009328
(Geobacillus thermodenitrificans NG80-2)

0.0

144) leuS
( YP_006991870.1 )

leucyl-tRNA synthetase

NC_019425
(Carnobacterium maltaromaticum LMA28)

0.0

145) leuS
( YP_001647354.1 )

leucyl-tRNA synthetase

NC_010184
(Bacillus weihenstephanensis KBAB4)

0.0

146) leuS
( YP_003464819.1 )

hypothetical protein

NC_013891
(Listeria seeligeri SLCC3954)

0.0

147) leuS
( YP_006679286.1 )

leucyl-tRNA synthetase

NC_018586
(Listeria monocytogenes SLCC2540)

0.0

148) leuS
( YP_006205896.1 )

leucyl-tRNA synthetase

NC_017728
(Listeria monocytogenes 07PF0776)

0.0

149) LMRG_01307
( YP_005962775.1 )

leucyl-tRNA synthetase

NC_017544
(Listeria monocytogenes 10403S)

0.0

150) leuS
( YP_006673476.1 )

leucyl-tRNA synthetase

NC_018584
(Listeria monocytogenes ATCC 19117)

0.0

151) M642_06250
( YP_008272113.1 )

leucyl-tRNA synthetase

NC_021823
(Listeria monocytogenes C1-387)

0.0

152) leuS
( YP_002758370.1 )

leucyl-tRNA synthetase

NC_012488
(Listeria monocytogenes Clip81459)

0.0

153) leuS
( YP_014280.1 )

leucyl-tRNA synthetase

NC_002973
(Listeria monocytogenes F2365)

0.0

154) leuS
( YP_002349868.1 )

leucyl-tRNA synthetase

NC_011660
(Listeria monocytogenes HCC23)

0.0

155) LM220_15800
( YP_008289912.1 )

leucyl-tRNA synthetase

NC_021830
(Listeria monocytogenes J1-220)

0.0

156) M640_07285
( YP_008302003.1 )

leucyl-tRNA synthetase

NC_021839
(Listeria monocytogenes J1776)

0.0

157) M644_07640
( YP_008284119.1 )

leucyl-tRNA synthetase

NC_021827
(Listeria monocytogenes J1817)

0.0

158) M645_07820
( YP_008304994.1 )

leucyl-tRNA synthetase

NC_021840
(Listeria monocytogenes J1926)

0.0

159) M637_11300
( YP_008276055.1 )

leucyl-tRNA synthetase

NC_021824
(Listeria monocytogenes J2-064)

0.0

160) M638_11030
( YP_008278845.1 )

leucyl-tRNA synthetase

NC_021825
(Listeria monocytogenes J2-1091)

0.0

161) leuS
( YP_006754796.1 )

leucyl-tRNA synthetase

NC_018642
(Listeria monocytogenes L312)

0.0

162) leuS
( YP_005926711.1 )

leuS

NC_017529
(Listeria monocytogenes L99)

0.0

163) leuS
( YP_007015253.1 )

Leucine--tRNA ligase

NC_019556
(Listeria monocytogenes LL195)

0.0

164) leuS
( YP_005947813.1 )

leucyl-tRNA synthetase

NC_017537
(Listeria monocytogenes M7)

0.0

165) M643_03220
( YP_008280239.1 )

leucyl-tRNA synthetase

NC_021826
(Listeria monocytogenes N1-011A)

0.0

166) M641_05150
( YP_008298542.1 )

leucyl-tRNA synthetase

NC_021838
(Listeria monocytogenes R2-502)

0.0

167) leuS
( YP_006690818.1 )

leucyl-tRNA synthetase

NC_018590
(Listeria monocytogenes SLCC2376)

0.0

168) leuS
( YP_006676350.1 )

leucyl-tRNA synthetase

NC_018585
(Listeria monocytogenes SLCC2378)

0.0

169) leuS
( YP_006693676.1 )

leucyl-tRNA synthetase

NC_018591
(Listeria monocytogenes SLCC2482)

0.0

170) leuS
( YP_006682122.1 )

leucyl-tRNA synthetase

NC_018587
(Listeria monocytogenes SLCC2755)

0.0

171) leuS
( YP_006696550.1 )

leucyl-tRNA synthetase

NC_018592
(Listeria monocytogenes SLCC5850)

0.0

172) leuS
( YP_006699326.1 )

leucyl-tRNA synthetase

NC_018593
(Listeria monocytogenes SLCC7179)

0.0

173) leuS
( YP_003413917.1 )

leucyl-tRNA synthetase

NC_013766
(Listeria monocytogenes 08-5578)

0.0

174) leuS
( YP_003416962.1 )

leucyl-tRNA synthetase

NC_013768
(Listeria monocytogenes 08-5923)

0.0

175) leuS
( NP_465185.1 )

leucyl-tRNA synthetase

NC_003210
(Listeria monocytogenes EGD-e)

0.0

176) LMKG_02977
( YP_005968627.1 )

leucyl-tRNA synthetase

NC_017546
(Listeria monocytogenes FSL R2-561)

0.0

177) LMOG_00027
( YP_005965643.1 )

leucyl-tRNA synthetase

NC_017545
(Listeria monocytogenes J0161)

0.0

178) leuS
( YP_006844759.1 )

leucyl-tRNA synthetase

NC_018704
(Amphibacillus xylanus NBRC 15112)

0.0

179) LMLG_1184
( YP_005971470.1 )

leucyl-tRNA synthetase

NC_017547
(Listeria monocytogenes Finland 1988)

0.0

180) M639_09005
( YP_008296363.1 )

leucyl-tRNA synthetase

NC_021837
(Listeria monocytogenes J2-031)

0.0

181) leuS
( YP_006685052.1 )

leucyl-tRNA synthetase

NC_018588
(Listeria monocytogenes SLCC2372)

0.0

182) leuS
( YP_006687986.1 )

leucyl-tRNA synthetase

NC_018589
(Listeria monocytogenes SLCC2479)

0.0

183) leuS
( YP_396045.1 )

leucyl-tRNA synthetase

NC_007576
(Lactobacillus sakei 23K)

0.0

184) leuS
( YP_849876.1 )

leucyl-tRNA synthetase

NC_008555
(Listeria welshimeri SLCC5334)

0.0

185) leuS
( NP_693228.1 )

leucyl-tRNA synthetase

NC_004193
(Oceanobacillus iheyensis HTE831)

0.0

186) leuS
( YP_007911774.1 )

leucyl-tRNA ligase

NC_021171
(Bacillus sp. 1NLA3E)

0.0

187) leuS
( YP_004855386.1 )

putative leucyl-tRNA synthetase

NC_016011
(Listeria ivanovii PAM 55)

0.0

188) leuS
( YP_001699832.1 )

leucyl-tRNA synthetase

NC_010382
(Lysinibacillus sphaericus C3-41)

0.0

189) leuS
( YP_006487021.1 )

leucyl-tRNA synthetase

NC_018081
(Enterococcus hirae ATCC 9790)

0.0

190) leuS
( YP_002869016.1 )

leucyl-tRNA synthetase

NC_012659
(Bacillus anthracis A0248)

0.0

191) leuS
( NP_847185.1 )

leucyl-tRNA synthetase

NC_003997
(Bacillus anthracis Ames)

0.0

192) leuS
( YP_021642.1 )

leucyl-tRNA synthetase

NC_007530
(Bacillus anthracis Ames Ancestor)

0.0

193) leuS
( YP_002817542.1 )

leucyl-tRNA synthetase

NC_012581
(Bacillus anthracis CDC 684)

0.0

194) H9401_4769
( YP_006211823.1 )

leucyl-tRNA synthetase

NC_017729
(Bacillus anthracis H9401)

0.0

195) leuS
( YP_030881.1 )

leucyl-tRNA synthetase

NC_005945
(Bacillus anthracis Sterne)

0.0

196) leuS
( YP_002752108.1 )

leucyl-tRNA synthetase

NC_012472
(Bacillus cereus 03BB102)

0.0

197) leuS
( YP_002453807.1 )

leucyl-tRNA synthetase

NC_011773
(Bacillus cereus AH820)

0.0

198) leuS
( NP_834441.1 )

leucyl-tRNA synthetase

NC_004722
(Bacillus cereus ATCC 14579 )

0.0

199) leuS
( YP_086065.1 )

leucyl-tRNA synthetase

NC_006274
(Bacillus cereus E33L)

0.0

200) bcf_23780
( YP_005121388.1 )

leucyl-tRNA synthetase

NC_016779
(Bacillus cereus F837/76)

0.0

201) leuS
( YP_006596400.1 )

leucyl-tRNA ligase

NC_018491
(Bacillus cereus FRI-35)

0.0

202) HD73_5048
( YP_007424147.1 )

Leucyl-tRNA synthetase

NC_020238
(Bacillus cereus HD73)

0.0

203) leuS
( YP_038784.1 )

leucyl-tRNA synthetase

NC_005957
(Bacillus thuringiensis 97-27)

0.0

204) leuS
( YP_897022.1 )

leucyl-tRNA synthetase

NC_008600
(Bacillus thuringiensis Al Hakam)

0.0

205) leuS
( YP_003666906.1 )

leucyl-tRNA synthetase

NC_014171
(Bacillus thuringiensis BMB171)

0.0

206) leuS
( YP_006929509.1 )

leucine--tRNA ligase LeuS

NC_018877
(Bacillus thuringiensis Bt407)

0.0

207) leuS
( YP_005574710.1 )

leucyl-tRNA synthetase

NC_017208
(Bacillus thuringiensis CT-43)

0.0

208) H175_ch4838
( YP_007481296.1 )

Leucyl-tRNA synthetase

NC_020376
(Bacillus thuringiensis IS5056)

0.0

209) leuS
( YP_002340798.1 )

leucyl-tRNA synthetase

NC_011658
(Bacillus cereus AH187)

0.0

210) leuS
( NP_981175.1 )

leucyl-tRNA synthetase

NC_003909
(Bacillus cereus ATCC 10987)

0.0

211) leuS
( YP_003794459.1 )

leucyl-tRNA synthetase

NC_014335
(Bacillus cereus CI)

0.0

212) BCN_4647
( YP_005107180.1 )

leucyl-tRNA synthetase

NC_016771
(Bacillus cereus NC7401)

0.0

213) leuS
( YP_002532268.1 )

leucyl-tRNA synthetase

NC_011969
(Bacillus cereus Q1)

0.0

214) leuS
( YP_006606470.1 )

leucyl-tRNA ligase

NC_018500
(Bacillus thuringiensis HD-771)

0.0

215) leuS
( YP_006612537.1 )

leucyl-tRNA ligase

NC_018508
(Bacillus thuringiensis HD-789)

0.0

216) leuS
( YP_002448306.1 )

leucyl-tRNA synthetase

NC_011772
(Bacillus cereus G9842)

0.0

217) leuS
( YP_005568313.1 )

leucyl-tRNA synthetase

NC_017200
(Bacillus thuringiensis YBT-020)

0.0

218) MC28_4019
( YP_006830840.1 )

menaquinone-specific isochorismate synthase

NC_018693
(Bacillus thuringiensis MC28)

0.0

219) MY9_3033
( YP_006232822.1 )

leucyl-tRNA synthetase

NC_017743
(Bacillus sp. JS)

0.0

220) leuS
( YP_001376622.1 )

leucyl-tRNA synthetase

NC_009674
(Bacillus cytotoxicus NVH 391-98)

0.0

221) leuS
( YP_004878517.1 )

leucyl-tRNA synthetase

NC_016047
(Bacillus subtilis TU-B-10)

0.0

222) leuS
( YP_005492592.1 )

Leucyl-tRNA synthetase bacterial/mitochondrial, class Ia

NC_017138
(Bacillus megaterium WSH-002)

0.0

223) leuS
( YP_003867285.1 )

leucyl-tRNA synthetase

NC_014479
(Bacillus subtilis W23)

0.0

224) leuS
( YP_002771476.1 )

leucyl-tRNA synthetase

NC_012491
(Brevibacillus brevis NBRC 100599)

0.0

225) leuS
( YP_004885597.1 )

leucyl-tRNA synthetase

NC_016052
(Tetragenococcus halophilus NBRC 12172)

0.0

226) Bcoa_2427
( YP_004860385.1 )

leucyl-tRNA synthetase

NC_016023
(Bacillus coagulans 36D1)

0.0

227) leuS
( YP_003565284.1 )

leucyl-tRNA synthetase

NC_014019
(Bacillus megaterium QM B1551)

0.0

228) leuS
( YP_004569501.1 )

leucyl-tRNA synthetase

NC_015634
(Bacillus coagulans 2-6)

0.0

229) leuS
( YP_003600007.1 )

leucyl-tRNA synthetase

NC_014103
(Bacillus megaterium DSM 319)

0.0

230) leuS
( YP_007403180.1 )

leucyl-tRNA synthetase

NC_020210
(Geobacillus sp. GHH01)

0.0

231) GYMC52_2888
( YP_004133399.1 )

leucyl-tRNA synthetase

NC_014915
(Geobacillus sp. Y412MC52)

0.0

232) leuS
( YP_003251824.1 )

leucyl-tRNA synthetase

NC_013411
(Geobacillus sp. Y412MC61)

0.0

233) GTCCBUS3UF5_31990
( YP_004983601.1 )

leucyl-tRNA synthetase

NC_016593
(Geobacillus thermoleovorans CCB_US3_UF5)

0.0

234) leuS
( YP_148695.1 )

leucyl-tRNA synthetase

NC_006510
(Geobacillus kaustophilus HTA426)

0.0

235) GC56T3_0651
( YP_003670275.1 )

leucyl-tRNA synthetase

NC_014206
(Geobacillus sp. C56-T3)

0.0

236) leuS
( YP_004320986.1 )

leucine--tRNA ligase

NC_015278
(Aerococcus urinae ACS-120-V-Col10a)

0.0

237) leuS
( YP_003974444.1 )

leucyl-tRNA synthetase

NC_014639
(Bacillus atrophaeus 1942)

0.0

238) leuS
( YP_002369537.1 )

leucyl-tRNA synthetase

NC_011725
(Bacillus cereus B4264)

0.0

239) leuS
( YP_005558001.1 )

leucyl-tRNA synthetase

NC_017195
(Bacillus subtilis RO-NN-1)

0.0

240) leuS
( NP_390910.1 )

leucine--tRNA ligase

NC_000964
(Bacillus subtilis 168)

0.0

241) leuS
( YP_007535019.1 )

leucyl-tRNA synthetase LeuS

NC_020507
(Bacillus subtilis 6051-HGW)

0.0

242) leuS
( YP_004204855.1 )

leucyl-tRNA synthetase

NC_014976
(Bacillus subtilis BSn5)

0.0

243) A7A1_1644
( YP_007208465.1 )

leucyl-tRNA synthetase

NC_019896
(Bacillus subtilis BSP1)

0.0

244) leuS
( YP_006631130.1 )

leucyl-tRNA synthetase

NC_018520
(Bacillus subtilis QB928)

0.0

245) leuS
( YP_005562244.1 )

leucyl-tRNA synthetase

NC_017196
(Bacillus subtilis BEST195)

0.0

246) leuS
( YP_007427965.1 )

leucyl-tRNA synthetase

NC_020244
(Bacillus subtilis XF-1)

0.0

247) leuS
( YP_007663658.1 )

leucyl-tRNA ligase

NC_020832
(subtilis subtilis BAB-1)

0.0

248) leuS
( YP_002314794.1 )

leucyl-tRNA synthetase

NC_011567
(Anoxybacillus flavithermus WK1)

0.0

249) leuS
( YP_007187499.1 )

leucyl-tRNA ligase

NC_019842
(Bacillus amyloliquefaciens AS43.3)

0.0

250) leuS
( YP_006714507.1 )

leucyl-tRNA ligase

NC_006322
(Bacillus licheniformis DSM 13)

0.0

251) leuS
( YP_080312.1 )

leucyl-tRNA synthetase

NC_006270
(Bacillus licheniformis DSM 13)

0.0

252) leuS
( YP_005131470.1 )

leucyl-tRNA synthetase

NC_016784
(Bacillus amyloliquefaciens CAU B946)

0.0

253) leuS
( YP_001422314.1 )

leucyl-tRNA synthetase

NC_009725
(Bacillus amyloliquefaciens FZB42)

0.0

254) leuS
( YP_007444463.1 )

leucyl-tRNA ligase

NC_020272
(Bacillus amyloliquefaciens IT-45)

0.0

255) leuS
( YP_007498346.1 )

Leucine--tRNA ligase

NC_020410
(Bacillus amyloliquefaciens UCMB5036)

0.0

256) leuS
( YP_006329918.1 )

leucyl-tRNA synthetase

NC_017912
(Bacillus amyloliquefaciens Y2)

0.0

257) leuS
( YP_005422278.1 )

leucyl-tRNA synthetase

NC_017061
(Bacillus amyloliquefaciens YAU B9601-Y2)

0.0

258) leuS
( YP_008413841.1 )

leucyl-tRNA synthetase

NC_022075
(Bacillus amyloliquefaciens UCMB-5033)

0.0

259) leuS
( YP_008422087.1 )

leucyl-tRNA synthetase

NC_022081
(Bacillus amyloliquefaciens UCMB5113)

0.0

260) leuS
( YP_003921410.1 )

leucyl-tRNA synthetase

NC_014551
(Bacillus amyloliquefaciens DSM 7)

0.0

261) leuS
( YP_005546866.1 )

leucyl-tRNA synthetase

NC_017190
(Bacillus amyloliquefaciens LL3)

0.0

262) leuS
( YP_005542619.1 )

leucyl-tRNA synthetase

NC_017188
(Bacillus amyloliquefaciens TA208)

0.0

263) leuS
( YP_005551011.1 )

leucyl-tRNA synthetase

NC_017191
(Bacillus amyloliquefaciens XH7)

0.0

264) leuS
( YP_002560838.1 )

leucyl-tRNA synthetase

NC_011999
(Macrococcus caseolyticus JCSC5402)

0.0

265) leuS
( NP_244147.1 )

leucyl-tRNA synthetase

NC_002570
(Bacillus halodurans C-125)

0.0

266) leuS
( YP_008079328.1 )

leucyl-tRNA ligase LeuS

NC_021362
(Bacillus licheniformis 9945A)

0.0

267) leuS
( YP_804150.1 )

leucyl-tRNA synthetase

NC_008525
(Pediococcus pentosaceus ATCC 25745)

0.0

268) SLGD_01172
( YP_003471390.1 )

Leucyl-tRNA synthetase

NC_013893
(Staphylococcus lugdunensis HKU09-01)

0.0

269) leuS
( YP_005760289.1 )

leucyl-tRNA synthetase

NC_017353
(Staphylococcus lugdunensis N920143)

0.0

270) leuS
( YP_006015147.1 )

leucyl-tRNA synthetase

NC_017568
(Staphylococcus pseudintermedius ED99)

0.0

271) SPSINT_1524
( YP_004149688.1 )

leucyl-tRNA synthetase

NC_014925
(Staphylococcus pseudintermedius HKU10-03)

0.0

272) GY4MC1_0754
( YP_003988181.1 )

leucyl-tRNA synthetase

NC_014650
(Geobacillus sp. Y4.1MC1)

0.0

273) Geoth_0822
( YP_004586901.1 )

leucyl-tRNA synthetase

NC_015660
(Geobacillus thermoglucosidasius C56-YS93)

0.0

274) leuS
( YP_004032527.1 )

leucyl-tRNA synthetase

NC_014724
(Lactobacillus amylovorus GRL 1112)

0.0

275) leuS
( YP_004292797.1 )

leucyl-tRNA synthetase

NC_015214
(Lactobacillus acidophilus 30SC)

0.0

276) leuS
( YP_005854544.1 )

leucyl-tRNA synthetase

NC_017470
(Lactobacillus amylovorus GRL1118)

0.0

277) leuS
( YP_004561961.1 )

Leucyl-tRNA synthetase

NC_015602
(Lactobacillus kefiranofaciens ZW3)

0.0

278) leuS
( YP_253078.1 )

leucyl-tRNA synthetase

NC_007168
(Staphylococcus haemolyticus JCSC1435)

0.0

279) leuS
( YP_002950719.1 )

leucyl-tRNA synthetase

NC_012793
(Geobacillus sp. WCH70)

0.0

280) leuS
( YP_006795929.1 )

leucyl-tRNA ligase

NC_018673
(Leuconostoc carnosum JB16)

0.0

281) M493_14690
( REF_PRJNA208285:M493 )

leucyl-tRNA synthetase

NC_022080
(Geobacillus sp. JF8)

0.0

282) leuS
( NP_764986.1 )

leucyl-tRNA synthetase

NC_004461
(Staphylococcus epidermidis ATCC 12228)

0.0

283) leuS
( YP_188890.1 )

leucyl-tRNA synthetase

NC_002976
(Staphylococcus epidermidis RP62A)

0.0

284) leuS
( YP_007384758.1 )

leucyl-tRNA ligase

NC_020164
(Staphylococcus warneri SG1)

0.0

285) leuS
( YP_003425773.1 )

leucyl-tRNA synthetase

NC_013791
(Bacillus pseudofirmus OF4)

0.0

286) leuS
( YP_005174001.1 )

leucyl-tRNA synthetase

NC_016805
(Leuconostoc mesenteroides J18)

0.0

287) leuS
( YP_005005122.1 )

leucyl-tRNA synthetase

NC_016605
(Pediococcus claussenii ATCC BAA-344)

0.0

288) leuS
( YP_818121.1 )

leucyl-tRNA synthetase

NC_008531
(Leuconostoc mesenteroides ATCC 8293)

0.0

289) leuS
( YP_001727857.1 )

leucyl-tRNA synthetase

NC_010471
(Leuconostoc citreum KM20)

0.0

290) leuS
( YP_005078082.1 )

leucyl-tRNA synthetase

NC_016641
(Paenibacillus terrae HPL-003)

0.0

291) leuS
( YP_176366.1 )

leucyl-tRNA synthetase

NC_006582
(Bacillus clausii KSM-K16)

0.0

292) leuS
( YP_003602101.1 )

leucyl-tRNA synthetase

NC_014106
(Lactobacillus crispatus ST1)

0.0

293) leuS
( YP_006655318.1 )

leucyl-tRNA ligase

NC_018528
(Lactobacillus helveticus R0052)

0.0

294) leuS
( YP_004832632.1 )

leucyl-tRNA synthetase

NC_015975
(Lactobacillus ruminis ATCC 27782)

0.0

295) leuS
( YP_005863482.1 )

Leucyl-tRNA synthetase (Leucine--tRNA ligase) (LeuRS)

NC_017481
(Lactobacillus salivarius CECT 5713)

0.0

296) leuS
( YP_535335.1 )

leucyl-tRNA synthetase

NC_007929
(Lactobacillus salivarius UCC118)

0.0

297) leuS
( YP_003871590.1 )

leucyl-tRNA synthetase

NC_014483
(Paenibacillus polymyxa E681)

0.0

298) leuS
( YP_001577906.1 )

leucyl-tRNA synthetase

NC_010080
(Lactobacillus helveticus DPC 4571)

0.0

299) leuS
( YP_806126.1 )

leucyl-tRNA synthetase

NC_008526
(Lactobacillus casei ATCC 334)

0.0

300) LCBD_0930
( YP_005858969.1 )

leucyl-tRNA synthetase

NC_017474
(Lactobacillus casei BD-II)

0.0

301) leuS
( YP_001986894.1 )

leucyl-tRNA synthetase

NC_010999
(Lactobacillus casei BL23)

0.0

302) LC2W_0935
( YP_005855853.1 )

leucyl-tRNA synthetase

NC_017473
(Lactobacillus casei LC2W)

0.0

303) leuS
( YP_006750987.1 )

leucine--tRNA ligase

NC_018641
(Lactobacillus casei W56)

0.0

304) leuS
( YP_003292669.1 )

hypothetical protein

NC_013504
(Lactobacillus johnsonii FI9785)

0.0

305) leuS
( YP_005849650.1 )

leucyl-tRNA synthetase

NC_017467
(Lactobacillus helveticus H10)

0.0

306) LOCK919_0986
( YP_008199507.1 )

Leucyl-tRNA synthetase

NC_021721
(Lactobacillus casei LOCK919)

0.0

307) LCAZH_0826
( YP_003787924.1 )

leucyl-tRNA synthetase

NC_014334
(Lactobacillus casei Zhang)

0.0

308) LJP_0500
( YP_005861784.1 )

leucyl-tRNA synthetase

NC_017477
(Lactobacillus johnsonii DPC 6026)

0.0

309) leuS
( NP_964532.1 )

leucyl-tRNA synthetase

NC_005362
(Lactobacillus johnsonii NCC 533)

0.0

310) LBPG_00010
( YP_008446047.1 )

leucyl-tRNA synthetase

NC_022112
(Lactobacillus paracasei 8700:2)

0.0

311) LA14_1608
( YP_007938449.1 )

Leucyl-tRNA synthetase

NC_021181
(Lactobacillus acidophilus La-14)

0.0

312) leuS
( YP_194462.1 )

leucyl-tRNA synthetase

NC_006814
(Lactobacillus acidophilus NCFM)

0.0

313) lhe_1588
( YP_008236942.1 )

leucyl-tRNA synthetase

NC_021744
(Lactobacillus helveticus CNRZ32)

0.0

314) leuS
( YP_008049015.1 )

leucyl-tRNA synthetase

NC_017542
(Paenibacillus polymyxa M1)

0.0

315) PPSC2_c3659
( YP_003947855.1 )

leucyl-tRNA synthetase

NC_014622
(Paenibacillus polymyxa SC2)

0.0

316) leuS
( YP_619369.1 )

leucyl-tRNA synthetase

NC_008054
(Lactobacillus delbrueckii ATCC 11842)

0.0

317) LBU_1344
( YP_005852553.1 )

leucyl-tRNA synthetase

NC_017469
(Lactobacillus delbrueckii 2038)

0.0

318) leuS
( YP_813393.1 )

leucyl-tRNA synthetase

NC_008529
(Lactobacillus delbrueckii ATCC BAA-365)

0.0

319) leuS
( YP_004034495.1 )

leucyl-tRNA synthetase

NC_014727
(Lactobacillus delbrueckii ND02)

0.0

320) ST398NM01_1811
( YP_006195831.1 )

leucyl-tRNA synthetase

NC_017673
(Staphylococcus aureus 71193)

0.0

321) leuS
( YP_005739825.1 )

leucyl-tRNA synthetase

NC_017338
(Staphylococcus aureus JKD6159)

0.0

322) leuS
( YP_005742465.1 )

Leucyl-tRNA synthetase

NC_017340
(Staphylococcus aureus 04-02981)

0.0

323) leuS
( YP_006710543.1 )

leucyl-tRNA synthetase

NC_018608
(Staphylococcus aureus 08BA02176)

0.0

324) leuS
( YP_005758203.1 )

leucyl-tRNA synthetase

NC_017351
(Staphylococcus aureus 11819-97)

0.0

325) SAAG_01660
( YP_008449665.1 )

leucyl-tRNA synthetase

NC_022113
(Staphylococcus aureus 55/2053)

0.0

326) leuS
( YP_008485629.1 )

leucyl-tRNA synthetase

NC_022222
(Staphylococcus aureus 6850)

0.0

327) leuS
( YP_005750328.1 )

leucyl-tRNA synthetase

NC_017343
(Staphylococcus aureus ECT-R 2)

0.0

328) SAOV_1744
( YP_005737230.1 )

leucyl-tRNA synthetase

NC_017337
(Staphylococcus aureus ED133)

0.0

329) leuS
( YP_003282665.1 )

leucyl-tRNA synthetase

NC_013450
(Staphylococcus aureus ED98)

0.0

330) leuS
( YP_001316979.1 )

leucyl-tRNA synthetase

NC_009632
(Staphylococcus aureus JH1)

0.0

331) leuS
( YP_001247179.1 )

leucyl-tRNA synthetase

NC_009487
(Staphylococcus aureus JH9)

0.0

332) leuS
( YP_005755631.1 )

leucyl-tRNA synthetase

NC_017349
(Staphylococcus aureus LGA251)

0.0

333) M013TW_1774
( YP_005298199.1 )

leucyl-tRNA synthetase

NC_016928
(Staphylococcus aureus M013)

0.0

334) leuS
( YP_041229.1 )

leucyl-tRNA synthetase

NC_002952
(Staphylococcus aureus MRSA252)

0.0

335) leuS
( YP_001442336.1 )

leucyl-tRNA synthetase

NC_009782
(Staphylococcus aureus Mu3)

0.0

336) leuS
( NP_372284.1 )

leucyl-tRNA synthetase

NC_002758
(Staphylococcus aureus Mu50)

0.0

337) leuS
( NP_374868.1 )

leucyl-tRNA synthetase

NC_002745
(Staphylococcus aureus N315)

0.0

338) leuS
( YP_008588263.1 )

leucyl-tRNA synthetase

NC_022443
(Staphylococcus aureus SA40)

0.0

339) leuS
( YP_008585798.1 )

leucyl-tRNA synthetase

NC_022442
(Staphylococcus aureus SA957)

0.0

340) leuS
( YP_007583880.1 )

Leucine--tRNA ligase

NC_020536
(Staphylococcus aureus ST228)

0.0

341) leuS
( YP_007621594.1 )

Leucine--tRNA ligase

NC_020566
(Staphylococcus aureus ST228)

0.0

342) leuS
( YP_007623583.1 )

Leucine--tRNA ligase

NC_020568
(Staphylococcus aureus ST228)

0.0

343) leuS
( YP_007577893.1 )

Leucine--tRNA ligase

NC_020529
(Staphylococcus aureus ST228 (isolate=10388))

0.0

344) leuS
( YP_007619610.1 )

Leucine--tRNA ligase

NC_020564
(Staphylococcus aureus ST228 (isolate=10497))

0.0

345) leuS
( YP_007579901.1 )

Leucine--tRNA ligase

NC_020532
(Staphylococcus aureus ST228 (isolate=15532))

0.0

346) leuS
( YP_007581866.1 )

Leucine--tRNA ligase

NC_020533
(Staphylococcus aureus ST228 (isolate=16035))

0.0

347) leuS
( YP_007585847.1 )

Leucine--tRNA ligase

NC_020537
(Staphylococcus aureus ST228 (isolate=18412))

0.0

348) leuS
( YP_005734607.1 )

leucyl-tRNA synthetase

NC_017333
(Staphylococcus aureus ST398)

0.0

349) leuS
( YP_005747475.1 )

leucyl-tRNA synthetase

NC_017342
(Staphylococcus aureus TCH60)

0.0

350) leuS
( YP_005872522.1 )

leucyl-tRNA synthetase

NC_017491
(Lactobacillus rhamnosus ATCC 8530)

0.0

351) leuS
( YP_003173589.1 )

leucyl-tRNA synthetase

NC_013199
(Lactobacillus rhamnosus Lc 705)

0.0

352) LOCK900_0812
( YP_008202446.1 )

Leucyl-tRNA synthetase

NC_021723
(Lactobacillus rhamnosus LOCK900)

0.0

353) LOCK908_0914
( YP_008205417.1 )

Leucyl-tRNA synthetase

NC_021725
(Lactobacillus rhamnosus LOCK908)

0.0

354) leuS
( YP_008128606.1 )

leucine--tRNA ligase

NC_021554
(Staphylococcus aureus CA-347)

0.0

355) Bsel_1235
( YP_003699313.1 )

leucyl-tRNA synthetase

NC_014219
(Bacillus selenitireducens MLS10)

0.0

356) leuS
( YP_006238009.1 )

leucyl-tRNA synthetase

NC_017763
(Staphylococcus aureus HO 5096 0412)

0.0

357) leuS
( YP_417087.1 )

leucyl-tRNA synthetase

NC_007622
(Staphylococcus aureus RF122)

0.0

358) leuS
( YP_003170594.1 )

leucyl-tRNA synthetase

NC_013198
(Lactobacillus rhamnosus GG)

0.0

359) LRHM_0806
( YP_005865298.1 )

leucyl-tRNA synthetase

NC_017482
(Lactobacillus rhamnosus GG)

0.0

360) leuS
( YP_008168907.1 )

Leucine--tRNA ligase

NC_021670
(Staphylococcus aureus Bmb9393)

0.0

361) leuS
( YP_186641.1 )

leucyl-tRNA synthetase

NC_002951
(Staphylococcus aureus COL)

0.0

362) leuS
( YP_494398.1 )

leucyl-tRNA synthetase

NC_007793
(Staphylococcus aureus FPR3757)

0.0

363) leuS
( YP_005745076.1 )

leucyl-tRNA synthetase

NC_017341
(Staphylococcus aureus JKD6008)

0.0

364) BN843_17610
( YP_007868826.1 )

Leucyl-tRNA synthetase

NC_021059
(Staphylococcus aureus M1)

0.0

365) leuS
( YP_500378.1 )

leucyl-tRNA synthetase

NC_007795
(Staphylococcus aureus NCTC 8325)

0.0

366) leuS
( YP_001332685.1 )

leucyl-tRNA synthetase

NC_009641
(Staphylococcus aureus Newman)

0.0

367) SAT0131_01867
( YP_005753012.1 )

leucyl-tRNA synthetase

NC_017347
(Staphylococcus aureus T0131)

0.0

368) leuS
( YP_001575635.1 )

leucyl-tRNA synthetase

NC_010079
(Staphylococcus aureus TCH1516)

0.0

369) leuS
( YP_005731746.1 )

leucyl-tRNA synthetase

NC_017331
(Staphylococcus aureus TW20)

0.0

370) leuS
( YP_005291193.1 )

leucyl-tRNA synthetase

NC_016912
(Staphylococcus aureus VC40)

0.0

371) leuS
( YP_006745542.1 )

leucyl-tRNA ligase

NC_018631
(Leuconostoc gelidum JB7)

0.0

372) SAKOR_01701
( YP_008491889.1 )

Leucyl-tRNA synthetase

NC_022226
(Staphylococcus aureus CN1)

0.0

373) leuS
( YP_043804.1 )

leucyl-tRNA synthetase

NC_002953
(Staphylococcus aureus MSSA476)

0.0

374) leuS
( NP_646518.1 )

leucyl-tRNA synthetase

NC_003923
(Staphylococcus aureus MW2)

0.0

375) leuS
( YP_003772694.1 )

leucyl-tRNA synthetase

NC_014319
(Leuconostoc gasicomitatum LMG 18811)

0.0

376) SAMSHR1132_16080
( YP_005326118.1 )

leucyl-tRNA synthetase

NC_016941
(Staphylococcus aureus MSHR1132)

0.0

377) leuS
( YP_003620920.1 )

leucyl-tRNA synthetase

NC_014136
(Leuconostoc kimchii IMSNU 11154)

0.0

378) leuS
( YP_004704873.1 )

leucyl-tRNA synthetase

NC_015734
(Leuconostoc sp. C2)

0.0

379) Bcell_3314
( YP_004096287.1 )

leucyl-tRNA synthetase

NC_014829
(Bacillus cellulosilyticus DSM 2522)

0.0

380) leuS
( YP_004560281.1 )

leucyl-tRNA synthetase

NC_015601
(Erysipelothrix rhusiopathiae Fujisawa)

0.0

381) leuS
( YP_008074136.1 )

leucyl-tRNA ligase

NC_021354
(Erysipelothrix rhusiopathiae SY1027)

0.0

382) leuS
( YP_810425.1 )

leucyl-tRNA synthetase

NC_008528
(Oenococcus oeni PSU-1)

0.0

383) leuS
( YP_814295.1 )

leucyl-tRNA synthetase

NC_008530
(Lactobacillus gasseri ATCC 33323)

0.0

384) leuS
( YP_002885110.1 )

leucyl-tRNA synthetase

NC_012673
(Exiguobacterium sp. AT1b)

0.0

385) leuS
( YP_301096.1 )

leucyl-tRNA synthetase

NC_007350
(Staphylococcus saprophyticus ATCC 15305)

0.0

386) leuS
( YP_001814744.1 )

leucyl-tRNA synthetase

NC_010556
(Exiguobacterium sibiricum 255-15)

0.0

387) leuS
( YP_004841187.1 )

leucyl-tRNA synthetase

NC_015978
(Lactobacillus sanfranciscensis TMW 1.1304)

0.0

388) leuS
( YP_004642577.1 )

LeuS protein

NC_015690
(Paenibacillus mucilaginosus KNP414)

0.0

389) PM3016_5616
( YP_005315457.1 )

LeuS protein

NC_016935
(Paenibacillus mucilaginosus 3016)

0.0

390) B2K_28610
( YP_006192379.1 )

leucyl-tRNA synthetase

NC_017672
(Paenibacillus mucilaginosus K02)

0.0

391) leuS
( YP_006181463.1 )

leucyl-tRNA synthetase

NC_017668
(Halobacillus halophilus DSM 2266)

0.0

392) Theco_2421
( YP_007213527.1 )

leucyl-tRNA synthetase

NC_019897
(Thermobacillus composti KWC4)

0.0

393) leuS
( YP_001844170.1 )

leucyl-tRNA synthetase

NC_010610
(Lactobacillus fermentum IFO 3956)

0.0

394) Lp16_1014
( YP_008120846.1 )

leucine-tRNA synthetase

NC_021514
(Lactobacillus plantarum 16)

0.0

395) leuS
( YP_003062696.1 )

leucyl-tRNA synthetase

NC_012984
(Lactobacillus plantarum JDM1)

0.0

396) leuS
( YP_007986658.1 )

Leucyl-tRNA synthetase

NC_021224
(Lactobacillus plantarum P-8)

0.0

397) leuS
( YP_003924376.1 )

leucyl-tRNA synthetase

NC_014554
(Lactobacillus plantarum ST-III)

0.0

398) leuS
( YP_004889192.1 )

leucine-tRNA synthetase

NC_004567
(Lactobacillus plantarum WCFS1)

0.0

399) leuS
( YP_007414018.1 )

Leucine--tRNA ligase

NC_020229
(Lactobacillus plantarum ZJ316)

0.0

400) LC40_0860
( YP_005848945.1 )

Leucine--tRNA ligase

NC_017465
(Lactobacillus fermentum CECT 5716)

0.0

401) leuS
( YP_007995644.1 )

Leucyl-tRNA synthetase

NC_021235
(Lactobacillus fermentum F-6)

0.0

402) leuS
( YP_003241811.1 )

leucyl-tRNA synthetase

NC_013406
(Paenibacillus sp. Y412MC10)

0.0

403) leuS
( YP_006791832.1 )

Leucine--tRNA ligase

NC_018665
(Exiguobacterium antarcticum Eab7)

0.0

404) leuS
( YP_006726013.1 )

leucyl-tRNA synthetase

NC_018610
(Lactobacillus buchneri CD034)

0.0

405) leuS
( YP_795226.1 )

leucyl-tRNA synthetase

NC_008497
(Lactobacillus brevis ATCC 367)

0.0

406) Lbuc_1271
( YP_004398589.1 )

leucyl-tRNA synthetase

NC_015428
(Lactobacillus buchneri NRRL B-30929)

0.0

407) LVISKB_0907
( YP_007653747.1 )

Leucyl-tRNA synthetase

NC_020819
(Lactobacillus brevis KB290)

0.0

408) leuS
( YP_004726153.1 )

leucyl-tRNA synthetase

NC_015759
(Weissella koreensis KACC 15510)

0.0

409) leuS
( YP_001271889.1 )

leucyl-tRNA synthetase

NC_009513
(Lactobacillus reuteri DSM 20016)

0.0

410) leuS
( YP_008099025.1 )

leucyl-tRNA synthase

NC_021494
(Lactobacillus reuteri I5007)

0.0

411) leuS
( YP_001842224.1 )

leucyl-tRNA synthetase

NC_010609
(Lactobacillus reuteri JCM 1112)

0.0

412) N134_07230
( YP_008326729.1 )

leucyl-tRNA synthetase

NC_021872
(Lactobacillus reuteri TD1)

0.0

413) Spico_0089
( YP_004410713.1 )

leucyl-tRNA synthetase

NC_015436
(Sphaerochaeta coccoides DSM 17374)

0.0

414) leuS
( YP_004648811.1 )

leucine--tRNA ligase

NC_015697
(Lactobacillus reuteri SD2112)

0.0

415) leuS
( YP_003010931.1 )

leucyl-tRNA synthetase

NC_012914
(Paenibacillus sp. JDR-2)

0.0

416) Fisuc_1159
( YP_003249245.1 )

leucyl-tRNA synthetase

NC_013410
(Fibrobacter succinogenes S85)

0.0

417) leuS
( YP_005821599.1 )

leucyl-tRNA synthetase

NC_017448
(Fibrobacter succinogenes S85)

0.0

418) Spirs_0283
( YP_003802033.1 )

leucyl-tRNA synthetase

NC_014364
(Spirochaeta smaragdinae DSM 11293)

0.0

419) SpiBuddy_0042
( YP_004246081.1 )

leucyl-tRNA synthetase

NC_015152
(Sphaerochaeta globosa Buddy)

0.0

420) SpiGrapes_1871
( YP_005062675.1 )

leucyl-tRNA synthetase

NC_016633
(Sphaerochaeta pleomorpha Grapes)

0.0

421) Hoch_6458
( YP_003270820.1 )

leucyl-tRNA synthetase

NC_013440
(Haliangium ochraceum DSM 14365)

0.0

422) leuS
( YP_008435191.1 )

leucyl-tRNA synthetase

NC_022097
(Treponema pedis T A4)

0.0

423) Spith_0352
( YP_006044354.1 )

leucyl-tRNA synthetase

NC_017583
(Spirochaeta thermophila DSM 6578)

0.0

424) STHERM_c03870
( YP_003873632.1 )

leucyl-tRNA synthetase

NC_014484
(Spirochaeta thermophila DSM 6192)

0.0

425) leuS
( YP_004651810.1 )

leucyl-tRNA synthetase

NC_015702
(Parachlamydia acanthamoebae UV-7)

0.0

426) leuS
( YP_008311149.1 )

leucyl-tRNA synthetase

NC_021846
(Spiroplasma taiwanense CT-1)

0.0

427) Spiaf_2640
( YP_005476373.1 )

leucyl-tRNA synthetase

NC_017098
(Spirochaeta africana DSM 8902)

0.0

428) leuS
( YP_001996342.1 )

leucyl-tRNA synthetase

NC_011026
(Chloroherpeton thalassium ATCC 35110)

0.0

429) Rmar_0671
( YP_003289957.1 )

leucyl-tRNA synthetase

NC_013501
(Rhodothermus marinus DSM 4252)

0.0

430) Rhom172_2212
( YP_004825948.1 )

leucyl-tRNA synthetase

NC_015966
(Rhodothermus marinus SG0.5JP17-172)

0.0

431) leuS
( NP_662533.1 )

leucyl-tRNA synthetase

NC_002932
(Chlorobium tepidum TLS)

0.0

432) leuS
( YP_001998161.1 )

leucyl-tRNA synthetase

NC_011027
(Chlorobaculum parvum NCIB 8327)

0.0

433) Spica_2714
( YP_004699319.1 )

leucyl-tRNA synthetase

NC_015732
(Treponema caldaria DSM 7334)

0.0

434) leuS
( YP_445066.1 )

leucyl-tRNA synthetase

NC_007677
(Salinibacter ruber DSM 13855)

0.0

435) leuS
( NP_972938.1 )

leucyl-tRNA synthetase

NC_002967
(Treponema denticola ATCC 35405)

0.0

436) Tresu_0602
( YP_004364840.1 )

leucyl-tRNA synthetase

NC_015385
(Treponema succinifaciens DSM 2489)

0.0

437) leuS
( YP_003570999.1 )

leucyl-tRNA synthetase

NC_014032
(Salinibacter ruber M8)

0.0

438) I871_01340
( YP_008415412.1 )

leucyl-tRNA synthase

NC_022079
(Borrelia miyamotoi LB-2001)

0.0

439) leuS
( YP_002221911.1 )

leucyl-tRNA synthetase

NC_011229
(Borrelia duttonii Ly)

0.0

440) leuS
( YP_008046.1 )

leucyl-tRNA synthetase

NC_005861
(Candidatus Protochlamydia amoebophila UWE25)

0.0

441) leuS
( YP_945258.1 )

leucyl-tRNA synthetase

NC_008710
(Borrelia turicatae 91E135)

0.0

442) leuS
( YP_002222722.1 )

leucyl-tRNA synthetase

NC_011244
(Borrelia recurrentis A1)

0.0

443) leuS
( YP_768383.1 )

leucyl-tRNA synthetase

NC_008380
(Rhizobium leguminosarum 3841)

0.0

444) leuS
( YP_072699.1 )

leucyl-tRNA synthetase

NC_006156
(Borrelia garinii PBi)

0.0

445) Q7M_254
( YP_006272185.1 )

leucyl-tRNA synthetase

NC_017808
(Borrelia crocidurae Achema)

0.0

446) Emin_0201
( YP_001875101.1 )

leucyl-tRNA synthetase

NC_010644
(Elusimicrobium minutum Pei191)

0.0

447) leuS
( YP_006931416.1 )

leucyl-tRNA synthetase

NC_018887
(Borrelia afzelii HLJ01)

0.0

448) leuS
( YP_375533.1 )

leucyl-tRNA synthetase

NC_007512
(Chlorobium luteolum DSM 273)

0.0

449) leuS
( YP_001958994.1 )

leucyl-tRNA synthetase

NC_010831
(Chlorobium phaeobacteroides BS1)

0.0

450) leuS
( YP_004671622.1 )

leucyl-tRNA synthetase

NC_015713
(Simkania negevensis Z)

0.0

451) leuS
( YP_005592469.1 )

leucyl-tRNA synthetase

NC_017238
(Borrelia afzelii PKo)

0.0

452) Rleg_2339
( YP_002976152.1 )

leucyl-tRNA synthetase

NC_012850
(Rhizobium leguminosarum WSM1325)

0.0

453) leuS
( YP_002015208.1 )

leucyl-tRNA synthetase

NC_011059
(Prosthecochloris aestuarii DSM 271)

0.0

454) leuS
( YP_008292238.1 )

leucyl-tRNA synthetase

NC_021833
(Spiroplasma diminutum CUAS-1)

0.0

455) leuS
( YP_003799828.1 )

leucyl-tRNA synthetase

NC_014355
(Candidatus Nitrospira defluvii )

0.0

456) leuS
( YP_004527760.1 )

leucine--tRNA ligase

NC_015577
(Treponema azotonutricium ZAS-9)

0.0

457) Trebr_1433
( YP_004439988.1 )

leucyl-tRNA synthetase

NC_015500
(Treponema brennaborense DSM 12168)

0.0

458) leuS
( YP_008018145.1 )

leucyl-tRNA synthetase

NC_021280
(Spiroplasma chrysopicola DF-1)

0.0

459) leuS
( YP_006202944.1 )

LeuS protein

NC_017717
(Borrelia garinii BgVir)

0.0

460) BgCN_0255
( YP_006870947.1 )

leucyl-tRNA synthetase

NC_018747
(Borrelia garinii NMJW1)

0.0

461) leuS
( YP_379983.1 )

leucyl-tRNA synthetase

NC_007514
(Chlorobium chlorochromatii CaD3)

0.0

462) leuS
( YP_002017581.1 )

leucyl-tRNA synthetase

NC_011060
(Pelodictyon phaeoclathratiforme BU-1)

0.0

463) leuS
( YP_004400367.1 )

Leucyl tRNA synthetase

NC_015431
(Mycoplasma mycoides 95010)

0.0

464) leuS
( YP_004529908.1 )

leucine--tRNA ligase

NC_015578
(Treponema primitia ZAS-2)

0.0

465) leuS
( YP_005805358.1 )

leucyl-tRNA synthetase

NC_017403
(Borrelia burgdorferi JD1)

0.0

466) leuS
( NP_975686.1 )

leucyl-tRNA synthetase

NC_005364
(Mycoplasma mycoides PG1)

0.0

467) leuS
( YP_001939058.1 )

leucyl-tRNA synthetase

NC_010794
(Methylacidiphilum infernorum V4)

0.0

468) leuS
( YP_007811535.1 )

leucine--tRNA ligase

NC_021025
(Mycoplasma mycoides Gladysdale)

0.0

469) leuS
( YP_003709413.1 )

Leucyl-tRNA synthetase

NC_014225
(Waddlia chondrophila WSU 86-1044)

0.0

470) leuS
( YP_911031.1 )

leucyl-tRNA synthetase

NC_008639
(Chlorobium phaeobacteroides DSM 266)

0.0

471) leuS
( YP_001883687.1 )

leucyl-tRNA synthetase

NC_010673
(Borrelia hermsii DAH)

0.0

472) leuS
( YP_005806449.1 )

leucyl-tRNA synthetase

NC_017418
(Borrelia burgdorferi N40)

0.0

473) leuS
( YP_424624.1 )

leucyl-tRNA synthetase

NC_007633
(Mycoplasma capricolum ATCC 27343)

0.0

474) leuS
( YP_004777499.1 )

leucyl-tRNA synthetase

NC_015921
(Borrelia bissettii DN127)

0.0

475) leuS
( YP_008407435.1 )

leucyl-tRNA ligase

NC_022048
(Borrelia burgdorferi CA382)

0.0

476) leuS
( YP_002374774.1 )

leucyl-tRNA synthetase

NC_011728
(Borrelia burgdorferi ZS7)

0.0

477) leuS
( YP_001942664.1 )

leucyl-tRNA synthetase

NC_010803
(Chlorobium limicola DSM 245)

0.0

478) leuS
( NP_212385.1 )

leucyl-tRNA synthetase

NC_001318
(Borrelia burgdorferi B31)

0.0

479) leuS
( YP_004790076.1 )

leucyl-tRNA synthetase

NC_015946
(Mycoplasma putrefaciens KS1)

0.0

480) leuS
( YP_007885176.1 )

Leucyl-tRNA synthetase

NC_021083
(Mycoplasma putrefaciens Mput9231)

0.0

481) leuS
( YP_001130938.1 )

leucyl-tRNA synthetase

NC_009337
(Chlorobium phaeovibrioides DSM 265)

0.0

482) leuS
( YP_005230377.1 )

leucyl-tRNA synthetase

NC_016848
(Treponema pallidum CDC2)

0.0

483) leuS
( YP_007936392.1 )

leucine--tRNA ligase

NC_021179
(Treponema pallidum Fribourg-Blanc)

0.0

484) leuS
( YP_005222769.1 )

leucyl-tRNA synthetase

NC_016843
(Treponema pallidum Gauthier)

0.0

485) leuS
( YP_005221700.1 )

leucyl-tRNA synthetase

NC_016842
(Treponema pallidum SamoaD)

0.0

486) leuS
( YP_005631455.1 )

leucyl-tRNA synthetase

NC_017268
(Treponema pallidum Chicago)

0.0

487) leuS
( YP_005223830.1 )

leucyl-tRNA synthetase

NC_016844
(Treponema pallidum DAL-1)

0.0

488) leuS
( YP_006869897.1 )

leucine--tRNA ligase

NC_018722
(Treponema pallidum Mexico A)

0.0

489) leuS
( NP_219024.1 )

leucyl-tRNA synthetase

NC_000919
(Treponema pallidum Nichols)

0.0

490) leuS
( YP_008091426.1 )

leucine--tRNA ligase

NC_021490
(Treponema pallidum Nichols)

0.0

491) leuS
( YP_008026946.1 )

leucyl-tRNA synthetase

NC_021284
(Spiroplasma syrphidicola EA-1)

0.0

492) leuS
( YP_004673317.1 )

leucine--tRNA ligase

NC_015714
(Treponema paraluiscuniculi Cuniculi A)

0.0

493) leuS
( YP_005907548.1 )

leucyl-tRNA synthetase

NC_017521
(Mycoplasma leachii 99/014/6)

0.0

494) leuS
( YP_004047412.1 )

leucyl-tRNA synthetase

NC_014751
(Mycoplasma leachii PG50)

0.0

495) Caka_1388
( YP_003548577.1 )

leucyl-tRNA synthetase

NC_014008
(Coraliomargarita akajimensis DSM 45221)

0.0

496) leuS
( YP_004838656.1 )

leucyl-tRNA synthetase

NC_015977
(Roseburia hominis A2-183)

0.0

497) leuS
( YP_632229.1 )

leucyl-tRNA synthetase

NC_008095
(Myxococcus xanthus DK 1622)

0.0

498) lueS
( NP_868620.1 )

leucyl-tRNA synthetase

NC_005027
(Rhodopirellula baltica SH 1)

0.0

499) Amuc_1654
( YP_001878254.1 )

leucyl-tRNA synthetase

NC_010655
(Akkermansia muciniphila ATCC BAA-835)

0.0

500) ROI_24380
( YP_007832445.1 )

leucyl-tRNA synthetase, eubacterial and mitochondrial family

NC_021040
(Roseburia intestinalis M50/1)

0.0

501) RO1_13160
( YP_007777723.1 )

leucyl-tRNA synthetase, eubacterial and mitochondrial family

NC_021012
(Roseburia intestinalis XB6B4)

0.0

502) leuS
( YP_005811262.1 )

leucyl-tRNA synthetase

NC_017434
(Chlamydia trachomatis D-EC)

0.0

503) leuS
( YP_005812140.1 )

leucyl-tRNA synthetase

NC_017436
(Chlamydia trachomatis D-LC)

0.0

504) O176_01130
( YP_008467628.1 )

leucyl-tRNA synthetase

NC_022119
(Chlamydia trachomatis D/13-96)

0.0

505) O177_01130
( YP_008442337.1 )

leucyl-tRNA synthetase

NC_022109
(Chlamydia trachomatis D/14-96)

0.0

506) SOTOND1_00217
( YP_007732835.1 )

leucyl-tRNA synthetase

NC_020967
(Chlamydia trachomatis D/SotonD1)

0.0

507) SOTOND5_00216
( YP_007727328.1 )

leucyl-tRNA synthetase

NC_020943
(Chlamydia trachomatis D/SotonD5)

0.0

508) SOTOND6_00216
( YP_007733728.1 )

leucyl-tRNA synthetase

NC_020968
(Chlamydia trachomatis D/SotonD6)

0.0

509) leuS
( NP_219713.1 )

leucyl-tRNA synthetase

NC_000117
(Chlamydia trachomatis D/UW-3/CX)

0.0

510) leuS
( YP_005809412.1 )

leucyl-tRNA synthetase

NC_017431
(Chlamydia trachomatis E/11023)

0.0

511) leuS
( YP_005814002.1 )

leucyl-tRNA synthetase

NC_017439
(Chlamydia trachomatis E/150)

0.0

512) BOUR_00219
( YP_007736409.1 )

leucyl-tRNA synthetase

NC_020971
(Chlamydia trachomatis E/Bour)

0.0

513) SOTONE4_00215
( YP_007734618.1 )

leucyl-tRNA synthetase

NC_020969
(Chlamydia trachomatis E/SotonE4)

0.0

514) SOTONE8_00221
( YP_007726436.1 )

leucyl-tRNA synthetase

NC_020942
(Chlamydia trachomatis E/SotonE8)

0.0

515) leuS
( YP_006361015.1 )

leucyl-tRNA synthetase

NC_017952
(Chlamydia trachomatis E/SW3)

0.0

516) O169_01140
( YP_008465771.1 )

leucyl-tRNA synthetase

NC_022117
(Chlamydia trachomatis F/1-93)

0.0

517) O173_01135
( YP_008440492.1 )

leucyl-tRNA synthetase

NC_022107
(Chlamydia trachomatis F/11-96)

0.0

518) O170_01130
( YP_008439565.1 )

leucyl-tRNA synthetase

NC_022106
(Chlamydia trachomatis F/2-93)

0.0

519) O172_01130
( YP_008466698.1 )

leucyl-tRNA synthetase

NC_022118
(Chlamydia trachomatis F/6-94)

0.0

520) SOTONF3_00216
( YP_007730150.1 )

leucyl-tRNA synthetase

NC_020964
(Chlamydia trachomatis F/SotonF3)

0.0

521) leuS
( YP_006360140.1 )

leucyl-tRNA synthetase

NC_017951
(Chlamydia trachomatis F/SW4)

0.0

522) leuS
( YP_006361890.1 )

leucyl-tRNA synthetase

NC_017953
(Chlamydia trachomatis F/SW5)

0.0

523) leuS
( YP_005814927.1 )

leucyl-tRNA synthetase

NC_017440
(Chlamydia trachomatis G/11074)

0.0

524) leuS
( YP_005808481.1 )

leucyl-tRNA synthetase

NC_017430
(Chlamydia trachomatis G/11222)

0.0

525) leuS
( YP_005810334.1 )

leucyl-tRNA synthetase

NC_017432
(Chlamydia trachomatis G/9301)

0.0

526) leuS
( YP_005807561.1 )

leucyl-tRNA synthetase

NC_017429
(Chlamydia trachomatis G/9768)

0.0

527) SOTONG1_00216
( YP_007725539.1 )

leucyl-tRNA synthetase

NC_020941
(Chlamydia trachomatis G/SotonG1)

0.0

528) leuS
( YP_007539903.1 )

leucyl-tRNA synthetase

NC_020511
(Chlamydia trachomatis IU824)

0.0

529) leuS
( YP_007540779.1 )

leucyl-tRNA synthetase

NC_020512
(Chlamydia trachomatis IU888)

0.0

530) O180_01140
( YP_008469487.1 )

leucyl-tRNA synthetase

NC_022121
(Chlamydia trachomatis J/31-98)

0.0

531) leuS
( YP_008348907.1 )

leucyl-tRNA synthetase

NC_021892
(Chlamydia trachomatis J/6276tet1)

0.0

532) SOTONK1_00216
( YP_007731042.1 )

leucyl-tRNA synthetase

NC_020965
(Chlamydia trachomatis K/SotonK1)

0.0

533) leuS
( YP_005815838.1 )

leucyl-tRNA synthetase

NC_017441
(Chlamydia trachomatis Sweden2)

0.0

534) EUR_16570
( YP_007772833.1 )

leucyl-tRNA synthetase

NC_021010
(Eubacterium rectale DSM 17629)

0.0

535) ERE_32020
( YP_007843775.1 )

leucyl-tRNA synthetase

NC_021044
(Eubacterium rectale M104/1)

0.0

536) SOTONIA1_00218
( YP_007735514.1 )

leucyl-tRNA synthetase

NC_020970
(Chlamydia trachomatis Ia/SotonIa1)

0.0

537) SOTONIA3_00218
( YP_007724647.1 )

leucyl-tRNA synthetase

NC_020940
(Chlamydia trachomatis Ia/SotonIa3)

0.0

538) O178_01135
( YP_008468559.1 )

leucyl-tRNA synthetase

NC_022120
(Chlamydia trachomatis Ia20-97)

0.0

539) EUBREC_1999
( YP_002937874.1 )

leucyl-tRNA synthetase

NC_012781
(Eubacterium rectale ATCC 33656)

0.0

540) O175_01130
( YP_008441419.1 )

leucyl-tRNA synthetase

NC_022108
(Chlamydia trachomatis E/12-94)

0.0

541) leuS
( YP_008347015.1 )

leucyl-tRNA synthetase

NC_021890
(Chlamydia trachomatis RC-F(s)/342)

0.0

542) leuS
( YP_008345142.1 )

leucyl-tRNA synthetase

NC_021888
(Chlamydia trachomatis RC-F(s)/852)

0.0

543) leuS
( YP_001620244.1 )

leucyl-tRNA synthetase

NC_010163
(Acholeplasma laidlawii PG-8A)

0.0

544) CCU_12230
( YP_007796215.1 )

leucyl-tRNA synthetase, eubacterial and mitochondrial family

NC_021018
(Coprococcus sp. ART55/1)

0.0

545) leuS
( YP_001514114.1 )

leucyl-tRNA synthetase

NC_009922
(Alkaliphilus oremlandii OhILAs)

0.0

546) Rumal_3096
( YP_004106195.1 )

leucyl-tRNA synthetase

NC_014833
(Ruminococcus albus 7)

0.0

547) A363_00224
( YP_007731942.1 )

leucyl-tRNA synthetase

NC_020966
(Chlamydia trachomatis A/363)

0.0

548) A5291_00223
( YP_007723753.1 )

leucyl-tRNA synthetase

NC_020939
(Chlamydia trachomatis A/5291)

0.0

549) A7249_00223
( YP_007728226.1 )

leucyl-tRNA synthetase

NC_020944
(Chlamydia trachomatis A/7249)

0.0

550) leuS
( YP_328017.1 )

leucyl-tRNA synthetase

NC_007429
(Chlamydia trachomatis A/HAR-13)

0.0

551) leuS
( YP_005156038.1 )

leucyl-tRNA synthetase

NC_016798
(Chlamydia trachomatis A2497)

0.0

552) CTO_0229
( YP_005813036.1 )

leucyl-tRNA synthetase

NC_017437
(Chlamydia trachomatis A2497)

0.0

553) leuS
( YP_002888708.1 )

leucyl-tRNA synthetase

NC_012687
(Chlamydia trachomatis B/TZ1A828/OT)

0.0

554) O179_01125
( YP_008443251.1 )

leucyl-tRNA synthetase

NC_022110
(Chlamydia trachomatis J/27-97)

0.0

555) leuS
( YP_002887826.1 )

leucyl-tRNA synthetase

NC_012686
(Chlamydia trachomatis Jali20)

0.0

556) BN418_1961
( YP_007604058.1 )

Leucine--tRNA ligase

NC_020557
(Listeria monocytogenes La111)

0.0

557) BN419_1962
( YP_007607189.1 )

Leucine--tRNA ligase

NC_020558
(Listeria monocytogenes N53-1)

0.0

558) leuS
( YP_456852.1 )

leucyl-tRNA synthetase

NC_007716
(Aster yellows witches'-broom phytoplasma AYWB)

0.0

559) leuS
( YP_001798783.1 )

leucyl-tRNA synthetase

NC_010544
(Candidatus Phytoplasma australiense )

0.0

560) leuS
( YP_007996990.1 )

Leucyl-tRNA synthetase

NC_021236
(Candidatus Phytoplasma australiense NZSb11)

0.0

561) Turpa_0238
( YP_006438404.1 )

leucyl-tRNA synthetase

NC_018020
(Turneriella parva DSM 21527)

0.0

562) leuS
( NP_950990.1 )

leucyl-tRNA synthetase

NC_005303
(Onion yellows phytoplasma onion yellows)

0.0

563) leuS
( YP_053732.1 )

leucyl-tRNA synthetase

NC_006055
(Mesoplasma florum L1)

0.0

564) leuS
( YP_002930141.1 )

leucyl-tRNA synthetase

NC_012778
(Eubacterium eligens ATCC 27750)

0.0

565) Cphy_0938
( YP_001558061.1 )

leucyl-tRNA synthetase

NC_010001
(Clostridium phytofermentans ISDg)

0.0

566) FP2_02300
( YP_007836198.1 )

leucyl-tRNA synthetase, eubacterial and mitochondrial family

NC_021042
(Faecalibacterium prausnitzii L2/6)

0.0

567) leuS
( YP_006974500.1 )

putative leucyl-tRNA synthetase

NC_019391
(Chlamydia psittaci 01DC12)

0.0

568) leuS
( YP_006741774.1 )

leucyl-tRNA synthetase

NC_018627
(Chlamydia psittaci MN)

0.0

569) leuS
( YP_005664296.1 )

leucyl-tRNA synthetase

NC_017289
(Chlamydia psittaci 01DC11)

0.0

570) leuS
( YP_005667222.1 )

leucyl-tRNA synthetase

NC_017292
(Chlamydia psittaci 02DC15)

0.0

571) leuS
( YP_005665269.1 )

leucyl-tRNA synthetase

NC_017290
(Chlamydia psittaci 08DC60)

0.0

572) leuS
( YP_004422445.1 )

leucyl-tRNA synthetase

NC_015470
(Chlamydia psittaci 6BC)

0.0

573) leuS
( YP_005663300.1 )

leucyl-tRNA synthetase

NC_017287
(Chlamydia psittaci 6BC)

0.0

574) leuS
( YP_006733267.1 )

leucyl-tRNA synthetase

NC_018619
(Chlamydia psittaci 84/55)

0.0

575) leuS
( YP_005666244.1 )

leucyl-tRNA synthetase

NC_017291
(Chlamydia psittaci C19/98)

0.0

576) leuS
( YP_006734334.1 )

leucyl-tRNA synthetase

NC_018620
(Chlamydia psittaci GR9)

0.0

577) leuS
( YP_004064554.1 )

putative leucyl-tRNA synthetase

NC_014796
(Chlamydia psittaci RD1)

0.0

578) leuS
( YP_006735419.1 )

leucyl-tRNA synthetase

NC_018621
(Chlamydia psittaci VS225)

0.0

579) Bd0365
( NP_967361.1 )

leucyl-rRNA synthetase

NC_005363
(Bdellovibrio bacteriovorus HD100)

0.0

580) Oter_3868
( YP_001820742.1 )

leucyl-tRNA synthetase

NC_010571
(Opitutus terrae PB90-1)

0.0

581) leuS
( YP_001654537.1 )

leucyl-tRNA synthetase

NC_010287
(Chlamydia trachomatis 434/Bu)

0.0

582) L1115_00212
( YP_007714834.1 )

leucyl-tRNA synthetase

NC_020929
(Chlamydia trachomatis L1/115)

0.0

583) L11322_00213
( YP_007737299.1 )

leucyl-tRNA synthetase

NC_020972
(Chlamydia trachomatis L1/1322/p2)

0.0

584) L1224_00212
( YP_007738188.1 )

leucyl-tRNA synthetase

NC_020973
(Chlamydia trachomatis L1/224)

0.0

585) L1440_00214
( YP_007721962.1 )

leucyl-tRNA synthetase

NC_020937
(Chlamydia trachomatis L1/440/LN)

0.0

586) L225667R_00213
( YP_007715724.1 )

leucyl-tRNA synthetase

NC_020930
(Chlamydia trachomatis L2/25667R)

0.0

587) leuS
( YP_007852426.1 )

leucyl-tRNA ligase

NC_021052
(Chlamydia trachomatis L2/434/Bu(f))

0.0

588) leuS
( YP_007851485.1 )

leucyl-tRNA ligase

NC_021050
(Chlamydia trachomatis L2/434/Bu(i))

0.0

589) L2B795_00213
( YP_007722853.1 )

leucyl-tRNA synthetase

NC_020938
(Chlamydia trachomatis L2b/795)

0.0

590) L2B8200_00212
( YP_007729113.1 )

leucyl-tRNA synthetase

NC_020945
(Chlamydia trachomatis L2b/8200/07)

0.0

591) L2BAMS1_00212
( YP_007718395.1 )

leucyl-tRNA synthetase

NC_020933
(Chlamydia trachomatis L2b/Ams1)

0.0

592) L2BAMS2_00212
( YP_007719285.1 )

leucyl-tRNA synthetase

NC_020934
(Chlamydia trachomatis L2b/Ams2)

0.0

593) L2BAMS3_00212
( YP_007741746.1 )

leucyl-tRNA synthetase

NC_020977
(Chlamydia trachomatis L2b/Ams3)

0.0

594) L2BAMS4_00213
( YP_007742637.1 )

leucyl-tRNA synthetase

NC_020978
(Chlamydia trachomatis L2b/Ams4)

0.0

595) L2BAMS5_00213
( YP_007721071.1 )

leucyl-tRNA synthetase

NC_020936
(Chlamydia trachomatis L2b/Ams5)

0.0

596) L2BCAN1_00214
( YP_007720177.1 )

leucyl-tRNA synthetase

NC_020935
(Chlamydia trachomatis L2b/Canada1)

0.0

597) L2BCAN2_00213
( YP_007717504.1 )

leucyl-tRNA synthetase

NC_020932
(Chlamydia trachomatis L2b/Canada2)

0.0

598) L2BCV204_00212
( YP_007740856.1 )

leucyl-tRNA synthetase

NC_020976
(Chlamydia trachomatis L2b/CV204)

0.0

599) L2BLST_00212
( YP_007739966.1 )

leucyl-tRNA synthetase

NC_020975
(Chlamydia trachomatis L2b/LST)

0.0

600) L2BUCH2_00212
( YP_007716613.1 )

leucyl-tRNA synthetase

NC_020931
(Chlamydia trachomatis L2b/UCH-2)

0.0

601) leuS
( YP_004717344.1 )

leucyl-tRNA synthetase

NC_015744
(Chlamydia trachomatis L2c)

0.0

602) L3404_00212
( YP_007739078.1 )

leucyl-tRNA synthetase

NC_020974
(Chlamydia trachomatis L3/404/LN)

0.0

603) leuS
( YP_008350998.1 )

leucyl-tRNA synthetase

NC_021895
(Chlamydia trachomatis RC-F/69)

0.0

604) leuS
( YP_008347965.1 )

leucyl-tRNA synthetase

NC_021891
(Chlamydia trachomatis RC-J(s)/122)

0.0

605) leuS
( YP_008351921.1 )

leucyl-tRNA synthetase

NC_021896
(Chlamydia trachomatis RC-J/943)

0.0

606) leuS
( YP_008346102.1 )

leucyl-tRNA synthetase

NC_021889
(Chlamydia trachomatis RC-J/953)

0.0

607) leuS
( YP_008353769.1 )

leucyl-tRNA synthetase

NC_021898
(Chlamydia trachomatis RC-J/966)

0.0

608) leuS
( YP_008354693.1 )

leucyl-tRNA synthetase

NC_021899
(Chlamydia trachomatis RC-J/971)

0.0

609) leuS
( YP_008352842.1 )

leucyl-tRNA synthetase

NC_021897
(Chlamydia trachomatis RC-L2(s)/3)

0.0

610) leuS
( YP_008344222.1 )

leucyl-tRNA synthetase

NC_021887
(Chlamydia trachomatis RC-L2(s)/46)

0.0

611) leuS
( YP_008349865.1 )

leucyl-tRNA synthetase

NC_021893
(Chlamydia trachomatis RC-L2/55)

0.0

612) leuS
( YP_001653549.1 )

leucyl-tRNA synthetase

NC_010280
(Chlamydia trachomatis UCH-1)

0.0

613) leuS
( YP_006740734.1 )

leucyl-tRNA synthetase

NC_018626
(Chlamydia psittaci NJ1)

0.0

614) leuS
( YP_002284773.1 )

leucyl-tRNA synthetase

NC_011374
(Ureaplasma urealyticum ATCC 33699)

0.0

615) leuS
( NP_829476.1 )

leucyl-tRNA synthetase

NC_003361
(Chlamydophila caviae GPIC)

0.0

616) leuS
( YP_219986.1 )

leucyl-tRNA synthetase

NC_004552
(Chlamydophila abortus S26/3)

0.0

617) Isop_2280
( YP_004179407.1 )

leucyl-tRNA synthetase

NC_014962
(Isosphaera pallida ATCC 43644)

0.0

618) Aaci_0425
( YP_003183873.1 )

leucyl-tRNA synthetase

NC_013205
(Alicyclobacillus acidocaldarius DSM 446)

0.0

619) leuS
( YP_005517034.1 )

leucyl-tRNA synthetase

NC_017167
(Alicyclobacillus acidocaldarius Tc-4-1)

0.0

620) A11Q_2231
( YP_007646054.1 )

leucyl-rRNA synthetase

NC_020813
(Bdellovibrio exovorus JSS)

0.0

621) leuS
( YP_515308.1 )

leucyl-tRNA synthetase

NC_007899
(Chlamydophila felis Fe/C-56)

0.0

622) Ethha_0328
( YP_004090645.1 )

leucyl-tRNA synthetase

NC_014828
(Ethanoligenens harbinense YUAN-3)

0.0

623) leuS
( YP_007438336.1 )

leucyl-tRNA synthetase

NC_020248
(Chlamydia psittaci Mat116)

0.0

624) leuS
( NP_325924.1 )

leucyl-tRNA synthetase

NC_002771
(Mycoplasma pulmonis UAB CTIP)

0.0

625) Sinac_3050
( YP_007203026.1 )

leucyl-tRNA synthetase

NC_019892
(Singulisphaera acidiphila DSM 18658)

0.0

626) leuS
( YP_003937068.1 )

leucyl-tRNA synthetase

NC_014614
(Clostridium sticklandii DSM 519)

0.0

627) leuS
( NP_757774.1 )

leucyl-tRNA synthetase

NC_004432
(Mycoplasma penetrans HF-2)

0.0

628) Psta_1623
( YP_003370158.1 )

leucyl-tRNA synthetase

NC_013720
(Pirellula staleyi DSM 6068)

0.0

629) leuS
( NP_445160.1 )

leucyl-tRNA synthetase

NC_002179
(Chlamydophila pneumoniae AR39)

0.0

630) leuS
( NP_224361.1 )

leucyl-tRNA synthetase

NC_000922
(Chlamydophila pneumoniae CWL029)

0.0

631) leuS
( NP_300212.1 )

leucyl-tRNA synthetase

NC_002491
(Chlamydophila pneumoniae J138)

0.0

632) leuS
( NP_876430.1 )

leucyl-tRNA synthetase

NC_005043
(Chlamydophila pneumoniae TW-183)

0.0

633) leuS
( YP_005662180.1 )

leucyl-tRNA synthetase

NC_017285
(Chlamydophila pneumoniae LPCoLN)

0.0

634) Bdt_0357
( YP_007021332.1 )

leucyl-tRNA synthetase

NC_019567
(Bdellovibrio bacteriovorus Tiberius)

0.0

635) leuS
( YP_002004474.1 )

leucyl-tRNA synthetase

NC_011047
(Candidatus Phytoplasma mali AT)

0.0

636) FPR_03880
( YP_007799198.1 )

leucyl-tRNA synthetase, eubacterial and mitochondrial family

NC_021020
(Faecalibacterium prausnitzii SL3/3)

0.0

637) leuS
( YP_001752454.1 )

leucyl-tRNA synthetase

NC_010503
(Ureaplasma parvum ATCC 27815)

0.0

638) leuS
( NP_078205.1 )

leucyl-tRNA synthetase

NC_002162
(Ureaplasma parvum ATCC 700970)

0.0

639) leuS
( YP_006788977.1 )

leucyl-tRNA ligase LeuS

NC_018664
(Clostridium acidurici 9a)

0.0

640) leuS
( YP_003152942.1 )

leucyl-tRNA synthetase

NC_013171
(Anaerococcus prevotii DSM 20548)

0.0

641) leuS
( YP_001999799.1 )

leucyl-tRNA synthetase

NC_011025
(Mycoplasma arthritidis 158L3-1)

0.0

642) CC1_19310
( YP_007770071.1 )

leucyl-tRNA synthetase, eubacterial and mitochondrial family

NC_021009
(Coprococcus catus GD/7)

0.0

643) ELI_3047
( YP_003960979.1 )

leucyl-tRNA synthetase

NC_014624
(Eubacterium limosum KIST612)

0.0

644) Clole_1316
( YP_004308240.1 )

leucyl-tRNA synthetase

NC_015275
(Clostridium lentocellum DSM 5427)

0.0

645) CK5_25320
( YP_007805818.1 )

leucyl-tRNA synthetase, eubacterial and mitochondrial family

NC_021022
([Ruminococcus] obeum A2-162)

0.0

646) leuS
( YP_008583736.1 )

leucyl-tRNA synthetase

NC_022441
(Chlamydia pecorum P787)

0.0

647) leuS
( YP_008581887.1 )

leucyl-tRNA synthetase

NC_022439
(Chlamydia pecorum PV3056/3)

0.0

648) leuS
( YP_008582810.1 )

leucyl-tRNA synthetase

NC_022440
(Chlamydia pecorum W73)

0.0

649) leuS
( YP_004377611.1 )

leucyl-tRNA synthetase

NC_015408
(Chlamydophila pecorum E58)

0.0

650) CLS_38740
( YP_007850948.1 )

leucyl-tRNA synthetase

NC_021047
(Clostridium saccharolyticum K10)

0.0

651) leuS
( NP_296858.1 )

leucyl-tRNA synthetase

NC_002620
(Chlamydia muridarum Nigg)

0.0

652) leuS
( YP_001691931.1 )

leucyl-tRNA synthetase

NC_010376
(Finegoldia magna ATCC 29328)

0.0

653) CK1_11530
( YP_007782993.1 )

leucyl-tRNA synthetase

NC_021014
(Ruminococcus sp. SR1/5)

0.0

654) CK3_29100
( YP_007824881.1 )

leucyl-tRNA synthetase

NC_021035
(butyrate-producing bacterium SS3/4)

0.0

655) Closa_1685
( YP_003821904.1 )

leucyl-tRNA synthetase

NC_014376
(Clostridium saccharolyticum WM1)

0.0

656) leuS
( YP_006264713.1 )

leucyl-tRNA synthetase

NC_017803
(Actinoplanes sp. SE50/110)

0.0

657) leuS
( YP_003302844.1 )

Leucyl-tRNA synthetase

NC_013511
(Mycoplasma hominis PG21)

0.0

658) leuS
( YP_005269350.1 )

leucyl-tRNA synthetase

NC_016894
(Acetobacterium woodii DSM 1030)

0.0

659) Clocl_1028
( YP_005045629.1 )

leucyl-tRNA synthetase

NC_016627
(Clostridium clariflavum DSM 19732)

0.0

660) leuS
( YP_001618066.1 )

leucyl-tRNA synthetase

NC_010162
(Sorangium cellulosum So ce 56)

0.0

661) Desku_0441
( YP_004515866.1 )

leucyl-tRNA synthetase

NC_015573
(Desulfotomaculum kuznetsovii DSM 6115)

0.0

662) SCE1572_43065
( YP_008154968.1 )

leucyl-tRNA synthetase

NC_021658
(Sorangium cellulosum So0157-2)

2e-180

663) leuS
( YP_429441.1 )

leucyl-tRNA synthetase

NC_007644
(Moorella thermoacetica ATCC 39073)

3e-180

664) RTO_26330
( YP_007787604.1 )

leucyl-tRNA synthetase

NC_021015
([Ruminococcus] torques L2-14)

7e-180

665) Desca_1898
( YP_004497654.1 )

leucyl-tRNA synthetase

NC_015565
(Desulfotomaculum carboxydivorans CO-1-SRB)

8e-180

666) Slip_1669
( YP_003702993.1 )

leucyl-tRNA synthetase

NC_014220
(Syntrophothermus lipocalidus DSM 12680)

2e-179

667) CL2_10680
( YP_007789058.1 )

leucyl-tRNA synthetase

NC_021016
(butyrate-producing bacterium SSC/2)

1e-178

668) RUM_13040
( YP_007829439.1 )

leucyl-tRNA synthetase, eubacterial and mitochondrial family

NC_021039
(Ruminococcus champanellensis 18P13)

2e-178

669) leuS
( YP_005880675.1 )

leucyl-tRNA synthetase

NC_017503
(Mycoplasma gallisepticum F)

2e-178

670) leuS
( YP_004882676.1 )

leucyl-tRNA synthetase

NC_016048
(Oscillibacter valericigenes Sjm18-20)

3e-178

671) HMPREF0389_00536
( YP_005053844.1 )

leucyl-tRNA synthetase

NC_016630
(Filifactor alocis ATCC 35896)

4e-178

672) leuS
( YP_005071342.1 )

leucyl-tRNA synthetase

NC_016640
(Arthrospira platensis NIES-39)

1e-177

673) leuS
( NP_853215.1 )

leucyl-tRNA synthetase

NC_004829
(Mycoplasma gallisepticum R)

6e-178

674) leuS
( YP_005879983.1 )

leucyl-tRNA synthetase

NC_017502
(Mycoplasma gallisepticum R(high))

6e-178

675) leuS
( YP_006585856.1 )

leucyl-tRNA synthetase

NC_018412
(Mycoplasma gallisepticum CA06_2006.052-5-2P)

8e-178

676) leuS
( YP_006585103.1 )

leucyl-tRNA synthetase

NC_018411
(Mycoplasma gallisepticum NC06_2006.080-5-2P)

8e-178

677) leuS
( YP_006586606.1 )

leucyl-tRNA synthetase

NC_018413
(Mycoplasma gallisepticum NC08_2008.031-4-3P)

8e-178

678) leuS
( YP_006582074.1 )

leucyl-tRNA synthetase

NC_018407
(Mycoplasma gallisepticum NC95_13295-2-2P)

8e-178

679) leuS
( YP_006582841.1 )

leucyl-tRNA synthetase

NC_018408
(Mycoplasma gallisepticum NC96_1596-4-2P)

8e-178

680) leuS
( YP_006583604.1 )

leucyl-tRNA synthetase

NC_018409
(Mycoplasma gallisepticum NY01_2001.047-5-1P)

8e-178

681) leuS
( YP_006581319.1 )

leucyl-tRNA synthetase

NC_018406
(Mycoplasma gallisepticum VA94_7994-1-7P)

8e-178

682) leuS
( YP_006584350.1 )

leucyl-tRNA synthetase

NC_018410
(Mycoplasma gallisepticum WI01_2001.043-13-2P)

8e-178

683) leuS
( YP_001037662.1 )

leucyl-tRNA synthetase

NC_009012
(Clostridium thermocellum ATCC 27405)

4e-177

684) Clo1313_1020
( YP_005687539.1 )

leucyl-tRNA synthetase

NC_017304
(Clostridium thermocellum DSM 1313)

4e-177

685) leuS
( YP_001659573.1 )

leucyl-tRNA synthetase

NC_010296
(Microcystis aeruginosa NIES-843)

5e-177

686) leuS
( NP_561586.1 )

leucyl-tRNA synthetase

NC_003366
(Clostridium perfringens 13)

3e-176

687) leuS
( YP_697972.1 )

leucyl-tRNA synthetase

NC_008262
(Clostridium perfringens SM101)

3e-176

688) GEI7407_0169
( YP_007107726.1 )

leucyl-tRNA synthetase

NC_019703
(Geitlerinema sp. PCC 7407)

4e-176

689) Oscil6304_4513
( YP_007087950.1 )

leucyl-tRNA synthetase

NC_019693
(Oscillatoria acuminata PCC 6304)

6e-176

690) Cyan7822_5283
( YP_003890439.1 )

leucyl-tRNA synthetase

NC_014501
(Cyanothece sp. PCC 7822)

7e-176

691) Sta7437_1821
( YP_007132345.1 )

leucyl-tRNA synthetase

NC_019748
(Stanieria cyanosphaera PCC 7437)

2e-175

692) Mesil_1033
( YP_003684446.1 )

leucyl-tRNA synthetase

NC_014212
(Meiothermus silvanus DSM 9946)

2e-175

693) Anacy_3413
( YP_007157724.1 )

leucyl-tRNA synthetase

NC_019771
(Anabaena cylindrica PCC 7122)

3e-175

694) leuS
( YP_001089035.1 )

leucyl-tRNA ligase

NC_009089
(Clostridium difficile 630)

3e-175

695) leuS
( YP_003215383.1 )

leucyl-tRNA synthetase

NC_013315
(Clostridium difficile CD196)

3e-175

696) leuS
( YP_003218891.1 )

leucyl-tRNA synthetase

NC_013316
(Clostridium difficile R20291)

3e-175

697) ES1_07210
( YP_007839352.1 )

leucyl-tRNA synthetase, eubacterial and mitochondrial family

NC_021043
(Eubacterium siraeum V10Sc8a)

3e-175

698) Cal6303_4910
( YP_007139779.1 )

leucyl-tRNA synthetase

NC_019751
(Calothrix sp. PCC 6303)

4e-175

699) leuS
( YP_359254.1 )

leucyl-tRNA synthetase

NC_007503
(Carboxydothermus hydrogenoformans Z-2901)

4e-175

700) EUS_23420
( YP_007776227.1 )

leucyl-tRNA synthetase, eubacterial and mitochondrial family

NC_021011
(Eubacterium siraeum 70/3)

4e-175

701) Desru_1058
( YP_004544619.1 )

leucyl-tRNA synthetase

NC_015589
(Desulfotomaculum ruminis DSM 2154)

4e-175

702) CCALI_00923
( YP_008088879.1 )

leucyl-tRNA synthetase

NC_021487
(Chthonomonas calidirosea T49)

5e-175

703) leuS
( YP_400937.1 )

leucyl-tRNA synthetase

NC_007604
(Synechococcus elongatus PCC 7942)

1e-174

704) leuS
( YP_006737531.1 )

leucyl-tRNA synthetase

NC_018623
(Chlamydia psittaci M56)

7e-175

705) AMIS_15100
( YP_005461246.1 )

putative leucyl-tRNA synthetase

NC_017093
(Actinoplanes missouriensis 431)

2e-174

706) Syn7502_00016
( YP_007104326.1 )

leucyl-tRNA synthetase

NC_019702
(Synechococcus sp. PCC 7502)

2e-174

707) MCYN0372
( YP_007258206.1 )

Leucyl-tRNA synthetase

NC_019949
(Mycoplasma cynos C142)

3e-174

708) leuS
( YP_001211389.1 )

leucyl-tRNA synthetase

NC_009454
(Pelotomaculum thermopropionicum SI)

4e-174

709) Mahau_1713
( YP_004463716.1 )

leucyl-tRNA synthetase

NC_015520
(Mahella australiensis 50-1 BON)

4e-174

710) Pse7367_0963
( YP_007101690.1 )

leucyl-tRNA synthetase

NC_019701
(Pseudanabaena sp. PCC 7367)

8e-174

711) leuS
( YP_172884.1 )

leucyl-tRNA synthetase

NC_006576
(Synechococcus elongatus PCC6301)

9e-174

712) Cha6605_3873
( YP_007098368.1 )

leucyl-tRNA synthetase

NC_019697
(Chamaesiphon minutus PCC 6605)

1e-173

713) leuS
( YP_002373367.1 )

leucyl-tRNA synthetase

NC_011726
(Cyanothece sp. PCC 8801)

1e-173

714) Nos7524_2415
( YP_007075854.1 )

leucyl-tRNA synthetase

NC_019684
(Nostoc sp. PCC 7524)

1e-173

715) Calkro_1446
( YP_004024121.1 )

leucyl-tRNA synthetase

NC_014720
(Caldicellulosiruptor kronotskyensis 2002)

2e-173

716) Syn6312_1305
( YP_007061025.1 )

leucyl-tRNA synthetase

NC_019680
(Synechococcus sp. PCC 6312)

2e-173

717) leuS
( YP_003192660.1 )

leucyl-tRNA synthetase

NC_013216
(Desulfotomaculum acetoxidans DSM 771)

2e-173

718) leuS
( YP_003138567.1 )

leucyl-tRNA synthetase

NC_013161
(Cyanothece sp. PCC 8802)

2e-173

719) leuS
( YP_002573127.1 )

leucyl-tRNA synthetase

NC_012034
(Caldicellulosiruptor bescii DSM 6725)

3e-173

720) Calhy_1471
( YP_003992557.1 )

leucyl-tRNA synthetase

NC_014652
(Caldicellulosiruptor hydrothermalis 108)

3e-173

721) Csac_1819
( YP_001180595.1 )

leucyl-tRNA synthetase

NC_009437
(Caldicellulosiruptor saccharolyticus DSM 8903)

4e-173

722) Calow_1045
( YP_004002408.1 )

leucyl-tRNA synthetase

NC_014657
(Caldicellulosiruptor owensensis OL)

4e-173

723) Mrub_1074
( YP_003506858.1 )

leucyl-tRNA synthetase

NC_013946
(Meiothermus ruber DSM 1279)

5e-173

724) leuS
( YP_007879802.1 )

leucyl-tRNA ligase

NC_021081
(Meiothermus ruber DSM 1279)

5e-173

725) TherJR_2509
( YP_003641247.1 )

leucyl-tRNA synthetase

NC_014152
(Thermincola potens JR)

5e-173

726) COB47_1302
( YP_003840580.1 )

leucyl-tRNA synthetase

NC_014392
(Caldicellulosiruptor obsidiansis OB47)

6e-173

727) Calla_0643
( YP_004798272.1 )

leucyl-tRNA synthetase

NC_015949
(Caldicellulosiruptor lactoaceticus 6A)

1e-172

728) leuS
( YP_002483726.1 )

leucyl-tRNA synthetase

NC_011884
(Cyanothece sp. PCC 7425)

2e-172

729) leuS
( YP_754271.1 )

leucyl-tRNA synthetase

NC_008346
(Syntrophomonas wolfei Goettingen)

2e-172

730) Marpi_0359
( YP_005096105.1 )

leucyl-tRNA synthetase

NC_016751
(Marinitoga piezophila KA3)

3e-172

731) Cal7507_5836
( YP_007068984.1 )

leucyl-tRNA synthetase

NC_019682
(Calothrix sp. PCC 7507)

3e-172

732) Ocepr_0474
( YP_004057106.1 )

leucyl-tRNA synthetase

NC_014761
(Oceanithermus profundus DSM 14977)

3e-172

733) leuS
( YP_325428.1 )

leucyl-tRNA synthetase

NC_007413
(Anabaena variabilis ATCC 29413)

3e-172

734) Calkr_1236
( YP_004026357.1 )

leucyl-tRNA synthetase

NC_014721
(Caldicellulosiruptor kristjanssonii 177R1B)

4e-172

735) leuS
( NP_781040.1 )

leucyl-tRNA synthetase

NC_004557
(Clostridium tetani E88)

4e-172

736) Clopa_1241
( YP_007939908.1 )

leucyl-tRNA synthetase

NC_021182
(Clostridium pasteurianum BC1)

4e-172

737) Osc7112_1185
( YP_007114148.1 )

leucyl-tRNA synthetase

NC_019729
(Oscillatoria nigro-viridis PCC 7112)

5e-172

738) Mic7113_0700
( YP_007120018.1 )

leucyl-tRNA synthetase

NC_019738
(Microcoleus sp. PCC 7113)

7e-172

739) Amet_2314
( YP_001320130.1 )

leucyl-tRNA synthetase

NC_009633
(Alkaliphilus metalliredigens QYMF)

8e-172

740) Riv7116_4568
( YP_007057534.1 )

leucyl-tRNA synthetase

NC_019678
(Rivularia sp. PCC 7116)

1e-171

741) MROS_1551
( YP_006527801.1 )

leucyl-tRNA synthetase

NC_018178
(Melioribacter roseus P3M-2)

1e-171

742) Aazo_4197
( YP_003722727.1 )

leucyl-tRNA synthetase

NC_014248
(Nostoc azollae 0708)

9e-172

743) leuS
( YP_001515391.1 )

leucyl-tRNA synthetase

NC_009925
(Acaryochloris marina MBIC11017)

2e-171

744) PCC7418_1974
( YP_007168354.1 )

leucyl-tRNA synthetase

NC_019779
(Halothece sp. PCC 7418)

2e-171

745) Hore_13370
( YP_002509082.1 )

leucyl-tRNA synthetase

NC_011899
(Halothermothrix orenii H 168)

1e-170

746) leuS
( YP_730582.1 )

leucyl-tRNA synthetase

NC_008319
(Synechococcus sp. CC9311)

9e-171

747) leuS
( NP_927027.1 )

leucyl-tRNA synthetase

NC_005125
(Gloeobacter violaceus PCC 7421)

2e-170

748) Cylst_1071
( YP_007146067.1 )

leucyl-tRNA synthetase

NC_019757
(Cylindrospermum stagnale PCC 7417)

2e-170

749) leuS
( YP_377114.1 )

leucyl-tRNA synthetase

NC_007513
(Synechococcus sp. CC9902)

2e-170

750) leuS
( YP_695110.1 )

leucyl-tRNA synthetase

NC_008261
(Clostridium perfringens ATCC 13124)

4e-170

751) leuS
( YP_877455.1 )

leucyl-tRNA synthetase

NC_008593
(Clostridium novyi NT)

4e-170

752) Cyan10605_2867
( YP_007162977.1 )

leucyl-tRNA synthetase

NC_019776
(Cyanobacterium aponinum PCC 10605)

4e-170

753) leuS
( YP_001867477.1 )

leucyl-tRNA synthetase

NC_010628
(Nostoc punctiforme PCC 73102)

4e-170

754) leuS
( NP_440622.1 )

leucyl-tRNA synthetase

NC_000911
(Synechocystis sp. PCC 6803)

5e-170

755) leuS
( YP_005382489.1 )

leucyl-tRNA synthetase

NC_017038
(Synechocystis sp. PCC 6803)

5e-170

756) leuS
( YP_005385658.1 )

leucyl-tRNA synthetase

NC_017039
(Synechocystis sp. PCC 6803)

5e-170

757) leuS
( YP_005408365.1 )

leucyl-tRNA synthetase

NC_017052
(Synechocystis sp. PCC 6803)

5e-170

758) leuS
( YP_005650680.1 )

leucyl-tRNA synthetase

NC_017277
(Synechocystis sp. PCC 6803)

5e-170

759) leuS
( YP_007450505.1 )

leucyl-tRNA synthetase

NC_020286
(Synechocystis sp. PCC 6803)

5e-170

760) Ferpe_0048
( YP_005470329.1 )

leucyl-tRNA synthetase

NC_017095
(Fervidobacterium pennivorans DSM 9078)

6e-170

761) leuS
( NP_487323.1 )

leucyl-tRNA synthetase

NC_003272
(Nostoc sp. PCC 7120)

6e-170

762) Dtur_1563
( YP_002353451.1 )

leucyl-tRNA synthetase

NC_011661
(Dictyoglomus turgidum DSM 6724)

2e-169

763) Nos7107_4769
( YP_007052440.1 )

leucyl-tRNA synthetase

NC_019676
(Nostoc sp. PCC 7107)

2e-169

764) LeuS
( YP_004709445.1 )

leucyl-tRNA synthetase

NC_015737
(Clostridium sp. SY8519)

9e-170

765) leuS
( YP_005847616.1 )

leucyl-tRNA synthetase

NC_017464
(Ignavibacterium album JCM 16511)

2e-169

766) Dacsa_2623
( YP_007172566.1 )

leucyl-tRNA synthetase

NC_019780
(Dactylococcopsis salina PCC 8305)

2e-169

767) leuS
( YP_002802498.1 )

leucyl-tRNA synthetase

NC_012563
(Clostridium botulinum Kyoto)

3e-169

768) leuS
( YP_001779813.1 )

leucyl-tRNA synthetase

NC_010516
(Clostridium botulinum Okra)

3e-169

769) leuS
( YP_002534061.1 )

leucyl-tRNA synthetase

NC_011978
(Thermotoga neapolitana DSM 4359)

4e-169

770) UCYN_00260
( YP_003421141.1 )

leucyl-tRNA synthetase

NC_013771
(Cyanobacterium sp. UCYN-A)

4e-169

771) Cyast_1429
( YP_007165042.1 )

leucyl-tRNA synthetase

NC_019778
(Cyanobacterium stanieri PCC 7202)

4e-169

772) leuS
( YP_381689.1 )

leucyl-tRNA synthetase

NC_007516
(Synechococcus sp. CC9605)

4e-169

773) leuS
( YP_002251273.1 )

leucyl-tRNA synthetase

NC_011297
(Dictyoglomus thermophilum H-6-12)

5e-169

774) leuS
( YP_001382590.1 )

leucyl-tRNA synthetase

NC_009697
(Clostridium botulinum ATCC 19397)

6e-169

775) leuS
( YP_001252730.1 )

leucyl-tRNA synthetase

NC_009495
(Clostridium botulinum ATCC 3502)

6e-169

776) leuS
( YP_001386143.1 )

leucyl-tRNA synthetase

NC_009698
(Clostridium botulinum Hall)

6e-169

777) H04402_00175
( YP_005676757.1 )

leucyl-tRNA synthetase

NC_017299
(Clostridium botulinum H04402 065)

1e-168

778) CBF_0218
( YP_005673224.1 )

leucyl-tRNA synthetase

NC_017297
(Clostridium botulinum 230613)

9e-169

779) leuS
( YP_001389549.1 )

leucyl-tRNA synthetase

NC_009699
(Clostridium botulinum Langeland)

9e-169

780) Glo7428_4678
( YP_007130271.1 )

leucyl-tRNA synthetase

NC_019745
(Gloeocapsa sp. PCC 7428)

2e-168

781) Clocel_3293
( YP_003844739.1 )

leucyl-tRNA synthetase

NC_014393
(Clostridium cellulovorans 743B)

3e-168

782) leuS
( NP_682888.1 )

leucyl-tRNA synthetase

NC_004113
(Thermosynechococcus elongatus BP-1)

4e-168

783) MHY_08640
( YP_007834518.1 )

leucyl-tRNA synthetase

NC_021041
(Megamonas hypermegale ART12/1)

1e-167

784) leuS
( YP_001278816.1 )

leucyl-tRNA synthetase

NC_009523
(Roseiflexus sp. RS-1)

1e-167

785) leuS
( YP_001227444.1 )

leucyl-tRNA synthetase

NC_009482
(Synechococcus sp. RCC307)

1e-167

786) Desaci_4049
( YP_006468246.1 )

leucyl-tRNA synthetase

NC_018068
(Desulfosporosinus acidiphilus SJ4)

6e-168

787) leuS
( YP_001305515.1 )

leucyl-tRNA synthetase

NC_009616
(Thermosipho melanesiensis BI429)

6e-168

788) leuS
( YP_001922274.1 )

leucyl-tRNA synthetase

NC_010723
(Clostridium botulinum Alaska E43)

8e-168

789) leuS
( YP_003104711.1 )

leucyl-tRNA synthetase

NC_013093
(Actinosynnema mirum DSM 43827)

9e-168

790) leuS
( YP_001887335.1 )

leucyl-tRNA synthetase

NC_010674
(Clostridium botulinum Eklund 17B)

2e-167

791) Amico_0688
( YP_003553547.1 )

leucyl-tRNA synthetase

NC_014011
(Aminobacterium colombiense DSM 12261)

3e-167

792) Clo1100_4071
( YP_005149977.1 )

leucyl-tRNA synthetase

NC_016791
(Clostridium sp. BNL1100)

4e-167

793) leuS
( YP_479064.1 )

leucyl-tRNA synthetase

NC_007776
(Synechococcus sp. JA-2-3B'a(2-13))

4e-167

794) leuS
( YP_004395212.1 )

leucyl-tRNA synthetase

NC_015425
(Clostridium botulinum BKT015925)

6e-167

795) leuS
( YP_001785514.1 )

leucyl-tRNA synthetase

NC_010520
(Clostridium botulinum Loch Maree)

6e-167

796) Plim_3733
( YP_003631744.1 )

leucyl-tRNA synthetase

NC_014148
(Planctomyces limnophilus DSM 3776)

1e-166

797) leuS
( YP_003496024.1 )

leucyl-tRNA synthetase

NC_013939
(Deferribacter desulfuricans SSM1)

1e-166

798) Ple7327_3352
( YP_007082125.1 )

leucyl-tRNA synthetase

NC_019689
(Pleurocapsa minor PCC 7327)

1e-166

799) Toce_0772
( YP_003825161.1 )

leucyl-tRNA synthetase

NC_014377
(Thermosediminibacter oceani DSM 16646)

2e-166

800) Theth_1781
( YP_004660920.1 )

leucyl-tRNA synthetase

NC_015707
(Thermotoga thermarum DSM 5069)

2e-166

801) leuS
( YP_928454.1 )

leucyl-tRNA synthetase

NC_008700
(Shewanella amazonensis SB2B)

3e-166

802) leuS
( YP_001734939.1 )

leucyl-tRNA synthetase

NC_010475
(Synechococcus sp. PCC 7002)

6e-166

803) Desgi_3363
( YP_007946384.1 )

leucyl-tRNA synthetase

NC_021184
(Desulfotomaculum gibsoniae DSM 7213)

6e-166

804) leuS
( YP_002861057.1 )

leucyl-tRNA synthetase

NC_012658
(Clostridium botulinum 657)

7e-166

805) leuS
( YP_001311654.1 )

leucyl-tRNA synthetase

NC_009617
(Clostridium beijerinckii NCIMB 8052)

2e-165

806) leuS
( YP_291516.1 )

leucyl-tRNA synthetase

NC_007335
(Prochlorococcus marinus NATL2A)

2e-165

807) leuS
( YP_001113850.1 )

leucyl-tRNA synthetase

NC_009253
(Desulfotomaculum reducens MI-1)

3e-165

808) Ilyop_0169
( YP_003966306.1 )

leucyl-tRNA synthetase

NC_014632
(Ilyobacter polytropus DSM 2926)

4e-165

809) Acfer_0634
( YP_003398343.1 )

leucyl-tRNA synthetase

NC_013740
(Acidaminococcus fermentans DSM 20731)

4e-165

810) Anamo_0594
( YP_006443570.1 )

leucyl-tRNA synthetase

NC_018024
(Anaerobaculum mobile DSM 13181)

5e-165

811) leuS
( YP_002522448.1 )

leucyl-tRNA synthetase

NC_011959
(Thermomicrobium roseum DSM 5159)

7e-165

812) Dole_2438
( YP_001530319.1 )

leucyl-tRNA synthetase

NC_009943
(Desulfococcus oleovorans Hxd3)

1e-164

813) leuS
( NP_897348.1 )

leucyl-tRNA synthetase

NC_005070
(Synechococcus sp. WH 8102)

2e-164

814) leuS
( YP_001471465.1 )

leucyl-tRNA synthetase

NC_009828
(Thermotoga lettingae TMO)

2e-164

815) leuS
( YP_003778462.1 )

leucyl-tRNA synthetase

NC_014328
(Clostridium ljungdahlii ATCC 49587)

3e-164

816) leuS
( YP_001681217.1 )

leucyl-tRNA synthetase

NC_010337
(Heliobacterium modesticaldum Ice1)

3e-164

817) leuS
( YP_006920832.1 )

leucyl-tRNA ligase LeuS

NC_018870
(Thermacetogenium phaeum DSM 12270)

3e-164

818) leuS
( YP_474702.1 )

leucyl-tRNA synthetase

NC_007775
(Synechococcus sp. JA-3-3Ab)

6e-164

819) leuS
( YP_002377160.1 )

leucyl-tRNA synthetase

NC_011729
(Cyanothece sp. PCC 7424)

8e-164

820) Tlie_0702
( YP_004932534.1 )

leucyl-tRNA synthetase

NC_016148
(Thermovirga lienii DSM 17291)

8e-164

821) Taci_0698
( YP_003317216.1 )

leucyl-tRNA synthetase

NC_013522
(Thermanaerovibrio acidaminovorans DSM 6589)

9e-164

822) Hprae_1340
( YP_005836633.1 )

leucyl-tRNA synthetase

NC_017455
(Halanaerobium praevalens DSM 2228)

1e-163

823) leuS
( YP_001567409.1 )

leucyl-tRNA synthetase

NC_010003
(Petrotoga mobilis SJ95)

2e-163

824) leuS
( YP_001411022.1 )

leucyl-tRNA synthetase

NC_009718
(Fervidobacterium nodosum Rt17-B1)

9e-164

825) Haur_4419
( YP_001547179.1 )

leucyl-tRNA synthetase

NC_009972
(Herpetosiphon aurantiacus DSM 785)

2e-163

826) leuS
( YP_290212.1 )

leucyl-tRNA synthetase

NC_007333
(Thermobifida fusca YX)

3e-163

827) Cyagr_0582
( YP_007045114.1 )

leucyl-tRNA synthetase

NC_019675
(Cyanobium gracile PCC 6307)

3e-163

828) Asphe3_19760
( YP_004241265.1 )

leucyl-tRNA synthetase

NC_015145
(Arthrobacter phenanthrenivorans Sphe3)

6e-163

829) leuS
( YP_001017515.1 )

leucyl-tRNA synthetase

NC_008820
(Prochlorococcus marinus MIT 9303)

7e-163

830) leuS
( YP_005205096.1 )

leucyl-tRNA synthetase

NC_016829
(Mycoplasma hyorhinis GDL-1)

1e-162

831) leuS
( YP_005904778.1 )

leucyl-tRNA synthetase

NC_017519
(Mycoplasma hyorhinis MCLD)

1e-162

832) leuS
( YP_007458314.1 )

leucine--tRNA ligase LeuS

NC_020291
(Clostridium saccharoperbutylacetonicum N1-4(HMT))

1e-162

833) Dehly_1143
( YP_003758760.1 )

leucyl-tRNA synthetase

NC_014314
(Dehalogenimonas lykanthroporepellens BL-DC-9)

1e-162

834) leuS
( NP_894547.1 )

leucyl-tRNA synthetase

NC_005071
(Prochlorococcus marinus MIT 9313)

1e-162

835) leuS
( YP_003856239.1 )

Leucyl-trna synthetase protein

NC_014448
(Mycoplasma hyorhinis HUB-1)

9e-163

836) Desor_5039
( YP_004972947.1 )

leucyl-tRNA synthetase

NC_016584
(Desulfosporosinus orientis DSM 765)

9e-163

837) MOS_262
( YP_007012835.1 )

leucyl-tRNA synthetase

NC_019552
(Mycoplasma hyorhinis SK76)

2e-162

838) Halha_1913
( YP_007315917.1 )

leucyl-tRNA synthetase

NC_019978
(Halobacteroides halobius DSM 5150)

2e-162

839) Sbal175_1096
( YP_006019679.1 )

leucyl-tRNA synthetase

NC_017571
(Shewanella baltica BA175)

2e-162

840) Sbal117_3406
( YP_006038579.1 )

leucyl-tRNA synthetase

NC_017579
(Shewanella baltica OS117)

2e-162

841) leuS
( YP_001051618.1 )

leucyl-tRNA synthetase

NC_009052
(Shewanella baltica OS155)

2e-162

842) leuS
( YP_001555869.1 )

leucyl-tRNA synthetase

NC_009997
(Shewanella baltica OS195)

2e-162

843) Sbal678_3462
( YP_005274652.1 )

leucyl-tRNA synthetase

NC_016901
(Shewanella baltica OS678)

2e-162

844) leuS
( YP_733134.1 )

leucyl-tRNA synthetase

NC_008321
(Shewanella sp. MR-4)

2e-162

845) leuS
( YP_001224983.1 )

leucyl-tRNA synthetase

NC_009481
(Synechococcus sp. WH 7803)

2e-162

846) Sgly_2452
( YP_004266738.1 )

leucyl-tRNA synthetase

NC_015172
(Syntrophobotulus glycolicus DSM 8271)

2e-162

847) leuS
( YP_561810.1 )

leucyl-tRNA synthetase

NC_007954
(Shewanella denitrificans OS217)

3e-162

848) leuS
( YP_002460769.1 )

leucyl-tRNA synthetase

NC_011830
(Desulfitobacterium hafniense DCB-2)

3e-162

849) leuS
( YP_519391.1 )

leucyl-tRNA synthetase

NC_007907
(Desulfitobacterium hafniense Y51)

3e-162

850) leuS
( YP_868642.1 )

leucyl-tRNA synthetase

NC_008577
(Shewanella sp. ANA-3)

4e-162

851) leuS
( YP_737118.1 )

leucyl-tRNA synthetase

NC_008322
(Shewanella sp. MR-7)

4e-162

852) TepRe1_1508
( YP_004460961.1 )

leucyl-tRNA synthetase

NC_015519
(Tepidanaerobacter acetatoxydans Re1)

5e-162

853) leuS
( YP_007272372.1 )

leucyl-tRNA synthetase

NC_019954
(Tepidanaerobacter acetatoxydans Re1)

5e-162

854) leuS
( YP_002357036.1 )

leucyl-tRNA synthetase

NC_011663
(Shewanella baltica OS223)

5e-162

855) leuS
( YP_001396966.1 )

leucyl-tRNA synthetase

NC_009706
(Clostridium kluyveri DSM 555)

1e-161

856) leuS
( YP_002473648.1 )

leucyl-tRNA synthetase

NC_011837
(Clostridium kluyveri NBRC 12016)

1e-161

857) leuS
( YP_001430232.1 )

leucyl-tRNA synthetase

NC_009767
(Roseiflexus castenholzii DSM 13941)

1e-161

858) Desmer_4033
( YP_006623735.1 )

leucyl-tRNA synthetase

NC_018515
(Desulfosporosinus meridiei DSM 13257)

1e-161

859) leuS
( YP_001367501.1 )

leucyl-tRNA synthetase

NC_009665
(Shewanella baltica OS185)

7e-162

860) Kfla_2370
( YP_003380244.1 )

leucyl-tRNA synthetase

NC_013729
(Kribbella flavida DSM 17836)

1e-161

861) leuS
( YP_590404.1 )

leucyl-tRNA synthetase

NC_008009
(Candidatus Koribacter versatilis Ellin345)

2e-161

862) B565_0903
( YP_004391555.1 )

Leucyl-tRNA synthetase, class Ia

NC_015424
(Aeromonas veronii B565)

3e-161

863) WQG_15580
( YP_007548626.1 )

Leucyl-tRNA synthetase

NC_020515
(Bibersteinia trehalosi USDA-ARS-USMARC-192)

3e-161

864) leuS
( NP_716799.1 )

leucyl-tRNA synthetase LeuS

NC_004347
(Shewanella oneidensis MR-1)

4e-161

865) leuS
( YP_962444.1 )

leucyl-tRNA synthetase

NC_008750
(Shewanella sp. W3-18-1)

4e-161

866) Sulac_2973
( YP_005258106.1 )

leucyl-tRNA synthetase

NC_016884
(Sulfobacillus acidophilus DSM 10332)

7e-161

867) leuS
( YP_004718606.1 )

leucyl-tRNA synthetase

NC_015757
(Sulfobacillus acidophilus TPY)

7e-161

868) Sput200_3007
( YP_006010873.1 )

leucyl-tRNA synthetase

NC_017566
(Shewanella putrefaciens 200)

8e-161

869) leuS
( YP_005091739.1 )

leucyl-tRNA synthetase

NC_016745
(Oceanimonas sp. GK1)

8e-161

870) Thexy_2006
( YP_004471694.1 )

leucyl-tRNA synthetase

NC_015555
(Thermoanaerobacterium xylanolyticum LX-11)

9e-161

871) Flexsi_1305
( YP_004603524.1 )

leucyl-tRNA synthetase

NC_015672
(Flexistipes sinusarabici DSM 4947)

9e-161

872) leuS
( YP_006559077.1 )

leucyl-tRNA synthetase

NC_018268
(Marinobacter sp. BSs20148)

9e-161

873) leuS
( YP_001184381.1 )

leucyl-tRNA synthetase

NC_009438
(Shewanella putrefaciens CN-32)

1e-160

874) leuS
( YP_005595607.1 )

leucyl-tRNA synthetase

NC_017243
(Brachyspira intermedia PWS/A)

1e-160

875) leuS
( YP_006761129.1 )

leucyl-tRNA synthetase LeuS

NC_018645
(Desulfobacula toluolica Tol2)

1e-160

876) leuS
( YP_001231868.1 )

leucyl-tRNA synthetase

NC_009483
(Geobacter uraniireducens Rf4)

1e-160

877) leuS
( YP_005430519.1 )

leucyl-tRNA synthetase

NC_017067
(Marinobacter hydrocarbonoclasticus ATCC 49840)

1e-160

878) leuS
( YP_004895908.1 )

leucyl-tRNA synthetase

NC_016077
(Acidaminococcus intestini RyC-MR95)

1e-160

879) leuS
( YP_002334323.1 )

leucyl-tRNA synthetase

NC_011653
(Thermosipho africanus TCF52B)

2e-160

880) Adeg_1804
( YP_003239742.1 )

leucyl-tRNA synthetase

NC_013385
(Ammonifex degensii KC4)

2e-160

881) leuS
( YP_003206250.1 )

leucine tRNA synthetase

NC_013260
(Candidatus Methylomirabilis oxyfera )

2e-160

882) Marky_1980
( YP_004368820.1 )

leucyl-tRNA synthetase

NC_015387
(Marinithermus hydrothermalis DSM 14884)

2e-160

883) Chro_4832
( YP_007094081.1 )

leucyl-tRNA synthetase

NC_019695
(Chroococcidiopsis thermalis PCC 7203)

2e-160

884) leuS
( YP_008034451.1 )

leucyl-tRNA ligase

NC_021286
(Idiomarina loihiensis GSL 199)

2e-160

885) leuS
( YP_155336.1 )

leucyl-tRNA synthetase

NC_006512
(Idiomarina loihiensis L2TR)

2e-160

886) Dret_1425
( YP_003198290.1 )

leucyl-tRNA synthetase

NC_013223
(Desulfohalobium retbaense DSM 5692)

3e-160

887) leuS
( YP_003916884.1 )

leucine-tRNA ligase

NC_014550
(Arthrobacter arilaitensis Re117)

3e-160

888) leuS
( NP_347283.1 )

leucyl-tRNA synthetase

NC_003030
(Clostridium acetobutylicum ATCC 824)

4e-160

889) leuS
( YP_004635310.1 )

leucyl-tRNA synthetase

NC_015687
(Clostridium acetobutylicum DSM 1731)

4e-160

890) leuS
( YP_005669792.1 )

leucyl-tRNA synthetase

NC_017295
(Clostridium acetobutylicum EA 2018)

4e-160

891) leuS
( YP_003984868.1 )

leucine--tRNA ligase

NC_014643
(Rothia dentocariosa ATCC 17931)

4e-160

892) leuS
( YP_960006.1 )

leucyl-tRNA synthetase

NC_008740
(Marinobacter aquaeolei VT8)

4e-160

893) leuS
( YP_002507722.1 )

leucyl-tRNA synthetase

NC_011898
(Clostridium cellulolyticum H10)

7e-160

894) leuS
( YP_001014817.1 )

leucyl-tRNA synthetase

NC_008819
(Prochlorococcus marinus NATL1A)

7e-160

895) Lepto7376_3835
( YP_007072826.1 )

leucyl-tRNA synthetase

NC_019683
(Leptolyngbya sp. PCC 7376)

1e-159

896) leuS
( YP_857738.1 )

leucyl-tRNA synthetase

NC_008570
(Aeromonas hydrophila ATCC 7966)

1e-159

897) leuS
( YP_006798812.1 )

leucyl-tRNA ligase

NC_018678
(Alteromonas macleodii English Channel 673)

1e-159

898) leuS
( YP_002722420.1 )

leucyl-tRNA synthetase

NC_012225
(Brachyspira hyodysenteriae WA1)

1e-159

899) leuS
( YP_087530.1 )

leucyl-tRNA synthetase

NC_006300
(Mannheimia succiniciproducens MBEL55E)

1e-159

900) leuS
( YP_005433795.1 )

putative leucyl-tRNA synthetase

NC_017068
(Selenomonas ruminantium TAM6421)

1e-159

901) leuS
( YP_719762.1 )

leucyl-tRNA synthetase

NC_008309
(Haemophilus somnus 129PT)

1e-159

902) Halsa_1703
( YP_003995480.1 )

leucyl-tRNA synthetase

NC_014654
(Halanaerobium hydrogeniformans sapolanicus)

2e-159

903) leuS
( YP_002603975.1 )

LeuS protein

NC_012108
(Desulfobacterium autotrophicum HRM2)

2e-159

904) Calni_0469
( YP_004050545.1 )

leucyl-tRNA synthetase

NC_014758
(Calditerrivibrio nitroreducens DSM 19672)

9e-160

905) GM18_3598
( YP_004200303.1 )

leucyl-tRNA synthetase

NC_014973
(Geobacter sp. M18)

2e-159

906) leuS
( YP_005986504.1 )

leucyl-tRNA synthetase

NC_017550
(Propionibacterium acnes ATCC 11828)

2e-159

907) leuS
( YP_001783813.1 )

leucyl-tRNA synthetase

NC_010519
(Haemophilus somnus 2336)

2e-159

908) leuS
( YP_831727.1 )

leucyl-tRNA synthetase

NC_008541
(Arthrobacter sp. FB24)

3e-159

909) leuS
( YP_006721261.1 )

leucyl-tRNA ligase

NC_007517
(Geobacter metallireducens GS-15)

3e-159

910) leuS
( YP_967305.1 )

leucyl-tRNA synthetase

NC_008751
(Desulfovibrio vulgaris DP4)

3e-159

911) Lebu_0511
( YP_003163413.1 )

leucyl-tRNA synthetase

NC_013192
(Leptotrichia buccalis DSM 1135)

4e-159

912) leuS
( YP_010415.1 )

leucyl-tRNA synthetase

NC_002937
(Desulfovibrio vulgaris Hildenborough)

4e-159

913) Deval_1104
( YP_005701903.1 )

leucyl-tRNA synthetase

NC_017310
(Desulfovibrio vulgaris RCH1)

4e-159

914) leuS
( YP_005944497.1 )

leucyl-tRNA synthetase

NC_017535
(Propionibacterium acnes 6609)

4e-159

915) leuS
( YP_003020598.1 )

leucyl-tRNA synthetase

NC_012918
(Geobacter sp. M21)

5e-159

916) leuS
( YP_004573885.1 )

leucyl-tRNA synthetase

NC_015635
(Microlunatus phosphovorus NM-1)

5e-159

917) leuS
( YP_055606.1 )

leucyl-tRNA synthetase

NC_006085
(Propionibacterium acnes KPA171202)

5e-159

918) leuS
( YP_004606667.1 )

leucyl-tRNA synthetase

NC_015673
(Corynebacterium resistens DSM 45100)

6e-159

919) leuS
( YP_008044592.1 )

leucyl-tRNA ligase

NC_021290
(Aeromonas hydrophila ML09-119)

6e-159

920) leuS
( YP_004226211.1 )

leucyl-tRNA synthetase

NC_015125
(Microbacterium testaceum StLB037)

1e-158

921) Rahaq2_3238
( YP_005201186.1 )

leucyl-tRNA synthetase

NC_016818
(Rahnella aquatilis CIP 78.65)

1e-158

922) Bmur_2055
( YP_003634329.1 )

leucyl-tRNA synthetase

NC_014150
(Brachyspira murdochii DSM 12563)

1e-158

923) Vpar_0964
( YP_003311925.1 )

leucyl-tRNA synthetase

NC_013520
(Veillonella parvula DSM 2008)

6e-159

924) leuS
( YP_268460.1 )

leucyl-tRNA synthetase

NC_003910
(Colwellia psychrerythraea 34H)

7e-159

925) leuS
( YP_005888753.1 )

leucyl-tRNA synthetase

NC_017509
(Mycoplasma hyopneumoniae 168)

7e-159

926) MHP168L_657
( YP_008026067.1 )

Leucyl-tRNA synthetase

NC_021283
(Mycoplasma hyopneumoniae 168-L)

7e-159

927) leuS
( YP_279441.1 )

leucyl-tRNA synthetase

NC_007295
(Mycoplasma hyopneumoniae J)

8e-159

928) leuS
( YP_006747813.1 )

leucyl-tRNA ligase

NC_018632
(Alteromonas macleodii ATCC 27126)

8e-159

929) leuS
( YP_001717990.1 )

leucyl-tRNA synthetase

NC_010424
(Candidatus Desulforudis audaxviator MP104C)

9e-159

930) leuS
( YP_006813135.1 )

leucyl-tRNA ligase

NC_018681
(Nocardia brasiliensis HUJEG-1)

9e-159

931) leuS
( YP_007404998.1 )

leucyl-tRNA synthetase

NC_020211
(Serratia marcescens WW4)

9e-159

932) syl
( YP_006704343.1 )

leucyl-tRNA synthetase

NC_018604
(Brachyspira pilosicoli WesB)

9e-159

933) leuS
( YP_001477439.1 )

leucyl-tRNA synthetase

NC_009832
(Serratia proteamaculans 568)

1e-158

934) Thein_1827
( YP_004626646.1 )

leucyl-tRNA synthetase

NC_015681
(Thermodesulfatator indicus DSM 15286)

1e-158

935) syl
( YP_006706981.1 )

leucyl-tRNA synthetase

NC_018607
(Brachyspira pilosicoli B2904)

1e-158

936) Acear_0581
( YP_003827189.1 )

leucyl-tRNA synthetase

NC_014378
(Acetohalobium arabaticum DSM 5501)

2e-158

937) leuS
( YP_002137573.1 )

leucyl-tRNA synthetase

NC_011146
(Geobacter bemidjiensis Bem)

2e-158

938) leuS
( YP_002960685.1 )

Leucyl-tRNA synthetase

NC_012806
(Mycoplasma conjunctivae HRC/581)

2e-158

939) Dde_2439
( YP_388931.1 )

leucyl-tRNA synthetase

NC_007519
(Desulfovibrio alaskensis G20)

2e-158

940) BPP43_00555
( YP_007233726.1 )

leucyl-tRNA synthetase

NC_019908
(Brachyspira pilosicoli P43/6/78)

2e-158

941) leuS
( YP_007616339.1 )

leucyl-tRNA ligase

NC_020561
(Sphingomonas sp. MM-1)

2e-158

942) LeuS
( YP_007562174.1 )

leucyl-tRNA synthetase

NC_020519
(Corynebacterium glutamicum ATCC 13032)

3e-158

943) leuS
( YP_005443452.1 )

leucyl-tRNA synthetase

NC_017079
(Caldilinea aerophila DSM 14535)

3e-158

944) leuS
( YP_002475527.1 )

leucyl-tRNA synthetase

NC_011852
(Haemophilus parasuis SH0165)

3e-158

945) leuS
( YP_001139827.1 )

leucyl-tRNA synthetase

NC_009342
(Corynebacterium glutamicum R)

4e-158

946) B711_0708
( YP_006739667.1 )

leucyl-tRNA synthetase

NC_018625
(Chlamydia psittaci CP3)

4e-158

947) RMDY18_11170
( YP_003362769.1 )

leucyl-tRNA synthetase

NC_013715
(Rothia mucilaginosa DY-18)

4e-158

948) leuS
( YP_008229044.1 )

leucyl-tRNA synthetase

NC_021741
(Serratia liquefaciens ATCC 27592)

4e-158

949) SerAS9_1179
( YP_004504580.1 )

leucyl-tRNA synthetase

NC_015567
(Serratia plymuthica AS9)

4e-158

950) SerAS12_1179
( YP_004499628.1 )

leucyl-tRNA synthetase

NC_015566
(Serratia sp. AS12)

4e-158

951) SerAS13_1179
( YP_006024042.1 )

leucyl-tRNA synthetase

NC_017573
(Serratia sp. AS13)

4e-158

952) leuS
( YP_002951833.1 )

leucyl-tRNA synthetase

NC_012796
(Desulfovibrio magneticus RS-1)

4e-158

953) leuS
( YP_007495196.1 )

Leucyl-tRNA synthetase

NC_020409
(Desulfovibrio piezophilus C1TLV30)

4e-158

954) leuS
( YP_001891666.1 )

leucyl-tRNA synthetase

NC_010677
(Francisella tularensis FSC147)

4e-158

955) Ping_1191
( YP_942624.1 )

leucyl-tRNA synthetase

NC_008709
(Psychromonas ingrahamii 37)

4e-158

956) leuS
( YP_003784995.1 )

leucyl-tRNA synthetase

NC_014330
(Brachyspira pilosicoli 95/1000)

4e-158

957) leuS
( YP_008067656.1 )

leucyl-tRNA ligase

NC_021351
(Corynebacterium glutamicum SCgG1)

5e-158

958) leuS
( YP_008070681.1 )

leucyl-tRNA ligase

NC_021352
(Corynebacterium glutamicum SCgG2)

5e-158

959) leuS
( YP_008123224.1 )

leucyl-tRNA ligase

NC_021521
(Haemophilus parasuis ZJ0906)

5e-158

960) leuS
( YP_749401.1 )

leucyl-tRNA synthetase

NC_008345
(Shewanella frigidimarina NCIMB 400)

5e-158

961) leuS
( YP_001762057.1 )

leucyl-tRNA synthetase

NC_010506
(Shewanella woodyi ATCC 51908)

5e-158

962) leuS
( YP_001606329.1 )

leucyl-tRNA synthetase

NC_010159
(Yersinia pestis Angola)

5e-158

963) leuS
( YP_003329681.1 )

leucyl-tRNA synthetase

NC_013552
(Dehalococcoides sp. VS)

1e-157

964) leuS
( YP_667110.1 )

leucyl-tRNA synthetase

NC_008245
(Francisella tularensis FSC 198)

5e-158

965) leuS
( YP_005831153.1 )

leucyl-tRNA synthetase

NC_017453
(Francisella tularensis NE061598)

5e-158

966) leuS
( YP_169978.1 )

leucyl-tRNA synthetase

NC_006570
(Francisella tularensis SCHU S4)

5e-158

967) leuS
( YP_005318114.1 )

leucyl-tRNA synthetase

NC_016937
(Francisella tularensis TI0902)

5e-158

968) leuS
( YP_005305660.1 )

leucyl-tRNA synthetase

NC_016933
(Francisella tularensis TIGB03)

5e-158

969) leuS
( YP_001140938.1 )

leucyl-tRNA synthetase

NC_009348
(Aeromonas salmonicida A449)

6e-158

970) leuS
( NP_992472.1 )

leucyl-tRNA synthetase

NC_005810
(Yersinia pestis 91001)

6e-158

971) leuS
( YP_005522259.1 )

leucyl-tRNA synthetase

NC_017168
(Yersinia pestis A1122)

6e-158

972) leuS
( YP_652396.1 )

leucyl-tRNA synthetase

NC_008150
(Yersinia pestis Antiqua)

6e-158

973) leuS
( YP_002347566.1 )

leucyl-tRNA synthetase

NC_003143
(Yersinia pestis CO92)

6e-158

974) leuS
( YP_005505620.1 )

leucyl-tRNA synthetase

NC_017154
(Yersinia pestis D106004)

6e-158

975) leuS
( YP_005509350.1 )

leucyl-tRNA synthetase

NC_017160
(Yersinia pestis D182038)

6e-158

976) leuS
( YP_005625045.1 )

leucyl-tRNA synthetase

NC_017265
(Yersinia pestis Harbin 35)

6e-158

977) leuS
( NP_668510.1 )

leucyl-tRNA synthetase

NC_004088
(Yersinia pestis KIM)

6e-158

978) leuS
( YP_647026.1 )

leucyl-tRNA synthetase

NC_008149
(Yersinia pestis Nepal516)

6e-158

979) leuS
( YP_001163982.1 )

leucyl-tRNA synthetase

NC_009381
(Yersinia pestis Pestoides F)

6e-158

980) leuS
( YP_003568476.1 )

leucyl-tRNA synthetase

NC_014029
(Yersinia pestis Z176003)

6e-158

981) leuS
( YP_001401888.1 )

leucyl-tRNA synthetase

NC_009708
(Yersinia pseudotuberculosis IP 31758)

6e-158

982) leuS
( YP_069641.1 )

leucyl-tRNA synthetase

NC_006155
(Yersinia pseudotuberculosis IP 32953)

6e-158

983) leuS
( YP_001871593.1 )

leucyl-tRNA synthetase

NC_010634
(Yersinia pseudotuberculosis PB1/+)

6e-158

984) leuS
( YP_001721741.1 )

leucyl-tRNA synthetase

NC_010465
(Yersinia pseudotuberculosis YPIII)

6e-158

985) leuS
( YP_227268.1 )

leucyl-tRNA synthetase

NC_006958
(Corynebacterium glutamicum ATCC 13032)

7e-158

986) DCF50_p2591
( YP_006914579.1 )

Leucyl-tRNA synthetase

NC_018867
(Dehalobacter sp. CF)

7e-158

987) leuS
( YP_006911593.1 )

Leucyl-tRNA synthetase

NC_018866
(Dehalobacter sp. DCA)

7e-158

988) leuS
( YP_001007185.1 )

leucyl-tRNA synthetase

NC_008800
(Yersinia enterocolitica 8081)

7e-158

989) Fbal_0825
( YP_003912108.1 )

leucyl-tRNA synthetase

NC_014541
(Ferrimonas balearica DSM 9799)

7e-158

990) leuS
( NP_739458.1 )

leucyl-tRNA synthetase

NC_004369
(Corynebacterium efficiens YS-314)

8e-158

991) leuS
( NP_602213.1 )

leucyl-tRNA synthetase

NC_003450
(Corynebacterium glutamicum ATCC 13032)

8e-158

992) leuS
( YP_008402851.1 )

leucine-tRNA ligase

NC_022040
(Corynebacterium glutamicum MB001)

8e-158

993) B601_0659
( YP_006736485.1 )

leucyl-tRNA synthetase

NC_018622
(Chlamydia psittaci WS/RT/E30)

8e-158

994) leuS
( YP_008137274.1 )

leucine--tRNA ligase LeuS

NC_021591
(Serratia odorifera 4Rx13)

8e-158

995) leuS
( YP_901401.1 )

leucyl-tRNA synthetase

NC_008609
(Pelobacter propionicus DSM 2379)

8e-158

996) leuS
( YP_008158040.1 )

leucyl-tRNA synthetase

NC_021659
(Serratia plymuthica S13)

9e-158

997) B603_0664
( YP_006738574.1 )

leucyl-tRNA synthetase

NC_018624
(Chlamydia psittaci WC)

1e-157

998) YE105_C1241
( YP_004297440.1 )

leucyl-tRNA synthetase

NC_015224
(Yersinia enterocolitica 105.5R(r))

1e-157

999) Y11_19181
( YP_006005417.1 )

leucyl-tRNA synthetase

NC_017564
(Yersinia enterocolitica Y11)

1e-157

1000) leuS
( YP_004946399.1 )

leucyl-tRNA synthetase

NC_016512
(Propionibacterium acnes P.acn17)

1e-157

1001) leuS
( YP_004944156.1 )

leucyl-tRNA synthetase

NC_016511
(Propionibacterium acnes P.acn31)

1e-157

1002) leuS
( YP_004955329.1 )

leucyl-tRNA synthetase

NC_016516
(Propionibacterium acnes P.acn33)

1e-157

1003) Tsac_0122
( YP_006390757.1 )

leucyl-tRNA synthetase

NC_017992
(Thermoanaerobacterium saccharolyticum JW/SL-YS485)

2e-157

1004) leuS
( NP_227983.1 )

leucyl-tRNA synthetase

NC_000853
(Thermotoga maritima MSB8)

2e-157

1005) Tmari_0166
( YP_007976517.1 )

Leucyl-tRNA synthetase

NC_021214
(Thermotoga maritima MSB8)

2e-157

1006) Selin_0893
( YP_004112189.1 )

leucyl-tRNA synthetase

NC_014836
(Desulfurispirillum indicum S5)

2e-157

1007) leuS
( YP_001121863.1 )

leucyl-tRNA synthetase

NC_009257
(Francisella tularensis WY96-3418)

2e-157

1008) leuS
( YP_005942139.1 )

leucyl-tRNA synthetase

NC_017534
(Propionibacterium acnes 266)

2e-157

1009) leuS
( YP_006850937.1 )

leucyl-tRNA ligase

NC_018707
(Propionibacterium acnes C1)

2e-157

1010) PAGK_1257
( YP_007887593.1 )

leucyl-tRNA synthetase

NC_021085
(Propionibacterium acnes HL096PA1)

2e-157

1011) leuS
( YP_003581118.1 )

leucine--tRNA ligase

NC_014039
(Propionibacterium acnes SK137)

2e-157

1012) leuS
( YP_007009333.1 )

leucyl-tRNA ligase

NC_019537
(Francisella tularensis F92)

2e-157

1013) leuS
( YP_007012045.1 )

leucyl-tRNA synthetase

NC_019551
(Francisella tularensis FSC200)

2e-157

1014) leuS
( YP_001428712.1 )

leucyl-tRNA synthetase

NC_009749
(Francisella tularensis FTNF002-00)

2e-157

1015) leuS
( YP_513895.1 )

leucyl-tRNA synthetase

NC_007880
(Francisella tularensis LVS)

2e-157

1016) leuS
( YP_763684.1 )

leucyl-tRNA synthetase

NC_008369
(Francisella tularensis OSU18)

2e-157

1017) PCNPT3_03740
( YP_007639528.1 )

leucyl-tRNA synthetase

NC_020802
(Psychromonas sp. CNPT3)

3e-157

1018) Sros_7138
( YP_003342576.1 )

leucyl-tRNA synthetase

NC_013595
(Streptosporangium roseum DSM 43021)

3e-157

1019) Tnap_0798
( YP_003346306.1 )

leucyl-tRNA synthetase

NC_013642
(Thermotoga naphthophila RKU-10)

3e-157

1020) leuS
( YP_180942.1 )

leucyl-tRNA synthetase

NC_002936
(Dehalococcoides ethenogenes 195)

3e-157

1021) FNFX1_0882
( YP_005825790.1 )

hypothetical protein

NC_017450
(Francisella novicida Fx1)

3e-157

1022) leuS
( YP_007871291.1 )

leucyl-tRNA ligase

NC_021064
(Propionibacterium avidum 44067)

3e-157

1023) leuS
( YP_001344050.1 )

leucyl-tRNA synthetase

NC_009655
(Actinobacillus succinogenes 130Z)

3e-157

1024) leuS
( YP_001244352.1 )

leucyl-tRNA synthetase

NC_009486
(Thermotoga petrophila RKU-1)

4e-157

1025) leuS
( YP_049415.1 )

leucyl-tRNA synthetase

NC_004547
(Pectobacterium atrosepticum SCRI1043)

4e-157

1026) leuS
( YP_007484585.1 )

leucine-tRNA ligase

NC_020387
(Dehalococcoides mccartyi BTF08)

5e-157

1027) Dbac_0057
( YP_003156603.1 )

leucyl-tRNA synthetase

NC_013173
(Desulfomicrobium baculatum DSM 4028)

5e-157

1028) HMPREF0409_01679
( YP_008020192.1 )

leucyl-tRNA synthetase

NC_021281
(Fusobacterium sp. 4_8)

5e-157

1029) Dalk_1193
( YP_002430364.1 )

leucyl-tRNA synthetase

NC_011768
(Desulfatibacillum alkenivorans AK-01)

5e-157

1030) leuS
( YP_143427.1 )

leucyl-tRNA synthetase

NC_006461
(Thermus thermophilus HB8)

6e-157

1031) Ser39006_1828
( YP_008522210.1 )

leucyl-tRNA synthetase class Ia

NC_022268
(Serratia sp. ATCC 39006)

6e-157

1032) leuS
( YP_941453.1 )

leucyl-tRNA synthetase

NC_008705
(Mycobacterium sp. KMS)

7e-157

1033) leuS
( YP_642545.1 )

leucyl-tRNA synthetase

NC_008146
(Mycobacterium sp. MCS)

7e-157

1034) leuS
( YP_008549812.1 )

leucyl-tRNA synthetase

NC_011138
(Alteromonas macleodii Deep ecotype)

7e-157

1035) leuS
( YP_001074019.1 )

leucyl-tRNA synthetase

NC_009077
(Mycobacterium sp. JLS)

8e-157

1036) FN3523_0917
( YP_005823971.1 )

leucyl-tRNA synthetase

NC_017449
(Francisella novicida 3523)

8e-157

1037) leuS
( YP_002537626.1 )

leucyl-tRNA synthetase

NC_011979
(Geobacter daltonii FRC-32)

8e-157

1038) leuS
( YP_005886165.1 )

leucyl-tRNA synthetase

NC_017506
(Marinobacter adhaerens HP15)

8e-157

1039) Kkor_0323
( YP_003145512.1 )

leucyl-tRNA synthetase

NC_013166
(Kangiella koreensis DSM 16069)

1e-156

1040) leuS
( YP_005794.1 )

leucyl-tRNA synthetase

NC_005835
(Thermus thermophilus HB27)

1e-156

1041) leuS
( YP_001363170.1 )

leucyl-tRNA synthetase

NC_009664
(Kineococcus radiotolerans SRS30216)

1e-156

1042) DehalGT_0253
( YP_003462076.1 )

leucyl-tRNA synthetase

NC_013890
(Dehalococcoides sp. GT)

1e-156

1043) leuS
( YP_898512.1 )

leucyl-tRNA synthetase

NC_008601
(Francisella novicida U112)

1e-156

1044) UMN179_01479
( YP_004420393.1 )

leucyl-tRNA synthetase

NC_015460
(Gallibacterium anatis UMN179)

1e-156

1045) leuS
( YP_008235396.1 )

leucyl-tRNA synthetase

NC_021743
(Mannheimia haemolytica D153)

1e-156

1046) leuS
( YP_008223957.1 )

leucyl-tRNA synthetase

NC_021739
(Mannheimia haemolytica D174)

1e-156

1047) leuS
( YP_007883396.1 )

leucine--tRNA ligase LeuS

NC_021082
(Mannheimia haemolytica M42548)

1e-156

1048) D650_17700
( YP_007666547.1 )

Leucyl-tRNA synthetase

NC_020833
(Mannheimia haemolytica USDA-ARS-USMARC-183)

1e-156

1049) D648_9870
( YP_007668499.1 )

Leucyl-tRNA synthetase

NC_020834
(Mannheimia haemolytica USDA-ARS-USMARC-185)

1e-156

1050) leuS
( YP_008338489.1 )

leucyl-tRNA synthetase

NC_021883
(Mannheimia haemolytica USMARC_2286)

1e-156

1051) leuS
( NP_622012.1 )

leucyl-tRNA synthetase

NC_003869
(Thermoanaerobacter tengcongensis MB4)

2e-156

1052) FN1517
( NP_602344.1 )

leucyl-tRNA synthetase

NC_003454
(Fusobacterium nucleatum ATCC 25586)

2e-156

1053) Nther_0537
( YP_001916721.1 )

leucyl-tRNA synthetase

NC_010718
(Natranaerobius thermophilus JW/NM-WN-LF)

9e-157

1054) TOL_0681
( YP_007681358.1 )

leucyl-tRNA synthetase

NC_020888
(Thalassolituus oleivorans MIL-1)

2e-156

1055) leuS
( YP_001738815.1 )

leucyl-tRNA synthetase

NC_010483
(Thermotoga sp. RQ2)

2e-156

1056) TtJL18_0246
( YP_006057947.1 )

leucyl-tRNA synthetase

NC_017587
(Thermus thermophilus JL-18)

2e-156

1057) leuS
( YP_006817378.1 )

leucyl-tRNA ligase

NC_018690
(Actinobacillus suis H91-0380)

2e-156

1058) leuS
( YP_008221301.1 )

leucyl-tRNA synthetase

NC_021738
(Mannheimia haemolytica D171)

2e-156

1059) Thewi_0350
( YP_004819127.1 )

leucyl-tRNA synthetase

NC_015958
(Thermoanaerobacter wiegelii Rt8.B1)

3e-156

1060) Tbis_2429
( YP_003653025.1 )

leucyl-tRNA synthetase

NC_014165
(Thermobispora bispora DSM 43833)

3e-156

1061) leuS
( YP_006802797.1 )

leucyl-tRNA ligase

NC_018679
(Alteromonas macleodii Balearic Sea AD45)

3e-156

1062) HMPREF0946_01200
( YP_008477499.1 )

leucyl-tRNA synthetase

NC_022196
(Fusobacterium sp. 3_1_36A2)

3e-156

1063) Sterm_0736
( YP_003307539.1 )

leucyl-tRNA synthetase

NC_013517
(Sebaldella termitidis ATCC 33386)

3e-156

1064) leuS
( YP_007483170.1 )

leucine-tRNA ligase

NC_020386
(Dehalococcoides mccartyi DCMB5)

4e-156

1065) leuS
( YP_307365.1 )

leucyl-tRNA synthetase

NC_007356
(Dehalococcoides sp. CBDB1)

4e-156

1066) Marme_3045
( YP_004314100.1 )

leucyl-tRNA synthetase

NC_015276
(Marinomonas mediterranea MMB-1)

5e-156

1067) DehaBAV1_0159
( YP_001213628.1 )

leucyl-tRNA synthetase

NC_009455
(Dehalococcoides sp. BAV1)

5e-156

1068) leuS
( NP_873605.1 )

leucyl-tRNA synthetase

NC_002940
(Haemophilus ducreyi 35000HP)

6e-156

1069) leuS
( YP_004761422.1 )

Leucyl-tRNA synthetase

NC_015859
(Corynebacterium variabile DSM 44702)

1e-155

1070) leuS
( YP_007372255.1 )

leucine--tRNA ligase LeuS

NC_020134
(Clostridium stercorarium DSM 8532)

1e-155

1071) Clst_0595
( YP_007678710.1 )

leucyl-tRNA synthetase

NC_020887
(Clostridium stercorarium DSM 8532)

1e-155

1072) leuS
( YP_001651886.1 )

leucyl-tRNA synthetase

NC_010278
(Actinobacillus pleuropneumoniae JL03)

1e-155

1073) leuS
( YP_001053573.1 )

leucyl-tRNA synthetase

NC_009053
(Actinobacillus pleuropneumoniae L20)

1e-155

1074) leuS
( YP_693667.1 )

leucine-tRNA synthetase

NC_008260
(Alcanivorax borkumensis SK2)

1e-155

1075) F7308_1367
( YP_004647893.1 )

Leucyl-tRNA synthetase

NC_015696
(Francisella sp. TX077308)

1e-155

1076) Glaag_2764
( YP_004434971.1 )

leucyl-tRNA synthetase

NC_015497
(Glaciecola sp. 4H-3-7+YE-5)

1e-155

1077) Anae109_2719
( YP_001379904.1 )

leucyl-tRNA synthetase

NC_009675
(Anaeromyxobacter sp. Fw109-5)

7e-156

1078) leuS
( YP_008292052.1 )

leucyl-tRNA synthetase

NC_021831
(Mycoplasma hyopneumoniae 7422)

8e-156

1079) leuS
( YP_288032.1 )

leucyl-tRNA synthetase

NC_007332
(Mycoplasma hyopneumoniae 7448)

8e-156

1080) Ththe16_0228
( YP_005639788.1 )

leucyl-tRNA synthetase

NC_017272
(Thermus thermophilus SG0.5JP17-16)

9e-156

1081) Tcr_0479
( YP_390749.1 )

leucyl-tRNA synthetase

NC_007520
(Thiomicrospira crunogena XCL-2)

9e-156

1082) leuS
( YP_008192600.1 )

leucyl-tRNA ligase

NC_021716
(Alteromonas macleodii English Channel 615)

1e-155

1083) leuS
( YP_003005259.1 )

leucyl-tRNA synthetase

NC_012912
(Dickeya zeae Ech1591)

1e-155

1084) leuS
( YP_006167671.1 )

leucyl-tRNA synthetase

NC_017663
(Escherichia coli P12b)

1e-155

1085) Dd586_1143
( YP_003332732.1 )

leucyl-tRNA synthetase

NC_013592
(Dickeya dadantii Ech586)

1e-155

1086) leuS
( YP_006118950.1 )

leucyl-tRNA synthetase

NC_017634
(Escherichia coli NRG 857C)

2e-155

1087) leuS
( YP_661142.1 )

leucyl-tRNA synthetase

NC_008228
(Pseudoalteromonas atlantica T6c)

2e-155

1088) Sde_3308
( YP_528775.1 )

leucyl-tRNA synthetase

NC_007912
(Saccharophagus degradans 2-40)

2e-155

1089) leuS
( YP_005726299.1 )

leucyl-tRNA synthetase

NC_017328
(Shigella flexneri 2002017)

2e-155

1090) leuS
( YP_003897296.1 )

leucyl-tRNA synthetase

NC_014532
(Halomonas elongata DSM 2581)

2e-155

1091) leuS
( NP_836340.1 )

leucyl-tRNA synthetase

NC_004741
(Shigella flexneri 2457T)

3e-155

1092) leuS
( NP_706568.2 )

leucyl-tRNA synthetase

NC_004337
(Shigella flexneri 301)

3e-155

1093) Tcur_1582
( YP_003299196.1 )

leucyl-tRNA synthetase

NC_013510
(Thermomonospora curvata DSM 43183)

3e-155

1094) leuS
( YP_006976819.1 )

leucyl-tRNA ligase

NC_019393
(Alteromonas macleodii AltDE1)

3e-155

1095) leuS
( YP_008171785.1 )

leucyl-tRNA ligase

NC_021710
(Alteromonas macleodii Ionian Sea U4)

3e-155

1096) leuS
( YP_008196190.1 )

leucyl-tRNA ligase

NC_021717
(Alteromonas macleodii Ionian Sea U7)

3e-155

1097) leuS
( YP_008175925.1 )

leucyl-tRNA ligase

NC_021712
(Alteromonas macleodii Ionian Sea U8)

3e-155

1098) leuS
( YP_008183868.1 )

leucyl-tRNA ligase

NC_021714
(Alteromonas macleodii Ionian Sea UM4b)

3e-155

1099) leuS
( YP_008179878.1 )

leucyl-tRNA ligase

NC_021713
(Alteromonas macleodii Ionian Sea UM7)

3e-155

1100) leuS
( YP_001980977.1 )

leucyl-tRNA synthetase

NC_010995
(Cellvibrio japonicus Ueda107)

3e-155

1101) leuS
( YP_002555536.1 )

Leucyl-tRNA synthetase

NC_011993
(Escherichia coli LF82)

3e-155

1102) leuS
( YP_003882066.1 )

leucyl-tRNA synthetase

NC_014500
(Dickeya dadantii 3937)

3e-155

1103) Desal_0650
( YP_002990255.1 )

leucyl-tRNA synthetase

NC_012881
(Desulfovibrio salexigens DSM 2638)

4e-155

1104) leuS
( YP_851771.1 )

leucyl-tRNA synthetase

NC_008563
(Escherichia coli APEC O1)

4e-155

1105) EcDH1_2984
( YP_006092902.1 )

leucyl-tRNA synthetase

NC_017625
(Escherichia coli DH1)

4e-155

1106) leuS
( YP_006128012.1 )

leucyl-tRNA synthetase

NC_017638
(Escherichia coli DH1)

4e-155

1107) ETEC_0670
( YP_006114260.1 )

leucyl-tRNA synthetase

NC_017633
(Escherichia coli ETEC H10407)

4e-155

1108) leuS
( YP_001729541.1 )

leucyl-tRNA synthetase

NC_010473
(Escherichia coli K-12)

4e-155

1109) leuS
( YP_001729642.1 )

leucyl-tRNA synthetase

NC_010473
(Escherichia coli K-12)

4e-155

1110) leuS
( YP_002925715.1 )

leucyl-tRNA synthetase

NC_012759
(Escherichia coli K-12)

4e-155

1111) leuS
( YP_007556199.1 )

leucyl-tRNA synthetase

NC_020518
(Escherichia coli K-12)

4e-155

1112) leuS
( YP_488933.1 )

leucyl-tRNA synthetase

NC_007779
(Escherichia coli K-12)

4e-155

1113) leuS
( NP_415175.1 )

leucyl-tRNA synthetase

NC_000913
(Escherichia coli K12)

4e-155

1114) leuS
( YP_539676.1 )

leucyl-tRNA synthetase

NC_007946
(Escherichia coli UTI89)

4e-155

1115) leuS
( YP_003687825.1 )

leucyl-tRNA synthetase

NC_014215
(Propionibacterium freudenreichii CIRM-BIA1)

4e-155

1116) leuS
( YP_007531854.1 )

leucyl-tRNA ligase

NC_020506
(Corynebacterium callunae DSM 20147)

5e-155

1117) leuS
( YP_002246977.1 )

leucyl-tRNA synthetase

NC_011295
(Coprothermobacter proteolyticus DSM 5265)

5e-155

1118) leuS
( YP_002760030.1 )

leucyl-tRNA synthetase

NC_012489
(Gemmatimonas aurantiaca T-27)

5e-155

1119) leuS
( YP_001725955.1 )

leucyl-tRNA synthetase

NC_010468
(Escherichia coli ATCC 8739)

5e-155

1120) leuS
( YP_002291986.1 )

leucyl-tRNA synthetase

NC_011415
(Escherichia coli SE11)

5e-155

1121) leuS
( YP_402257.1 )

leucyl-tRNA synthetase

NC_007606
(Shigella dysenteriae Sd197)

5e-155

1122) leuS
( YP_003008594.1 )

leucyl-tRNA synthetase

NC_012913
(Aggregatibacter aphrophilus NJ8700)

6e-155

1123) leuS
( YP_006132486.1 )

leucyl-tRNA synthetase

NC_017641
(Escherichia coli UMNK88)

6e-155

1124) Csal_2344
( YP_574392.1 )

leucyl-tRNA synthetase

NC_007963
(Chromohalobacter salexigens DSM 3043)

1e-154

1125) leuS
( YP_005803437.1 )

protein leuS

NC_017390
(Erwinia pyrifoliae DSM 12163)

1e-154

1126) leuS
( YP_002649478.1 )

leucyl-tRNA synthetase

NC_012214
(Erwinia pyrifoliae Ep1/96)

1e-154

1127) leuS
( YP_002328113.1 )

leucyl-tRNA synthetase

NC_011601
(Escherichia coli E2348/69)

1e-154

1128) leuS
( YP_006099891.1 )

leucyl-tRNA synthetase

NC_017628
(Escherichia coli IHE3034)

1e-154

1129) leuS
( YP_008570580.1 )

Leucine--tRNA ligase

NC_022370
(Escherichia coli PMV-1)

1e-154

1130) leuS
( YP_002390493.1 )

leucyl-tRNA synthetase

NC_011742
(Escherichia coli S88)

1e-154

1131) leuS
( YP_001879348.1 )

leucyl-tRNA synthetase

NC_010658
(Shigella boydii CDC 3083-94)

1e-154

1132) leuS
( NP_841196.1 )

leucyl-tRNA synthetase

NC_004757
(Nitrosomonas europaea ATCC 19718)

1e-154

1133) Q91_1664
( YP_006838201.1 )

leucyl-tRNA synthetase

NC_018697
(Cycloclasticus sp. P1; MCCC 1A01040)

5e-155

1134) leuS
( YP_002998448.1 )

leucyl-tRNA synthetase

NC_012892
(Escherichia coli BL21(DE3))

6e-155

1135) leuS
( YP_003053260.1 )

leucyl-tRNA synthetase

NC_012971
(Escherichia coli BL21(DE3))

6e-155

1136) leuS
( YP_003498411.1 )

Leucyl-tRNA synthetase

NC_013941
(Escherichia coli CB9615)

6e-155

1137) leuS
( NP_752663.1 )

leucyl-tRNA synthetase

NC_004431
(Escherichia coli CFT073)

6e-155

1138) leuS
( YP_006152834.1 )

leucyl-tRNA synthetase

NC_017652
(Escherichia coli clone D i14)

6e-155

1139) leuS
( YP_006147915.1 )

leucyl-tRNA synthetase

NC_017651
(Escherichia coli clone D i2)

6e-155

1140) leuS
( YP_002269278.1 )

leucyl-tRNA synthetase

NC_011353
(Escherichia coli EC4115)

6e-155

1141) leuS
( NP_286368.1 )

leucyl-tRNA synthetase

NC_002655
(Escherichia coli EDL933)

6e-155

1142) leuS
( YP_003037203.1 )

leucyl-tRNA synthetase

NC_012947
(Escherichia coli Escherichia coli BL21-Gold(DE3)pLysS AG)

6e-155

1143) leuS
( YP_003043832.1 )

leucyl-tRNA synthetase

NC_012967
(Escherichia coli REL606)

6e-155

1144) leuS
( YP_006157960.1 )

leucyl-tRNA synthetase

NC_017656
(Escherichia coli RM12579)

6e-155

1145) leuS
( NP_308707.1 )

leucyl-tRNA synthetase

NC_002695
(Escherichia coli Sakai)

6e-155

1146) leuS
( YP_003076645.1 )

leucyl-tRNA synthetase

NC_013008
(Escherichia coli TW14359)

6e-155

1147) leuS
( YP_006311523.1 )

leucyl-tRNA synthetase

NC_017906
(Escherichia coli Xuzhou21)

6e-155

1148) Daes_2821
( YP_004122563.1 )

leucyl-tRNA synthetase

NC_014844
(Desulfovibrio aespoeensis Aspo-2)

7e-155

1149) leuS
( YP_006111736.1 )

leucyl-tRNA synthetase

NC_017632
(Escherichia coli UM146)

7e-155

1150) leuS
( YP_407034.1 )

leucyl-tRNA synthetase

NC_007613
(Shigella boydii Sb227)

7e-155

1151) leuS
( YP_006094998.1 )

leucyl-tRNA synthetase

NC_017626
(Escherichia coli 042)

8e-155

1152) leuS
( YP_003233192.1 )

leucyl-tRNA synthetase

NC_013364
(Escherichia coli 11128)

8e-155

1153) leuS
( YP_003227785.1 )

leucyl-tRNA synthetase

NC_013361
(Escherichia coli 11368)

8e-155

1154) leuS
( YP_003220646.1 )

leucyl-tRNA synthetase

NC_013353
(Escherichia coli 12009)

8e-155

1155) leuS
( YP_006771298.1 )

leucyl-tRNA synthetase

NC_018650
(Escherichia coli 2009EL-2050)

8e-155

1156) leuS
( YP_006785488.1 )

leucyl-tRNA synthetase

NC_018661
(Escherichia coli 2009EL-2071)

8e-155

1157) leuS
( YP_006780348.1 )

leucyl-tRNA synthetase

NC_018658
(Escherichia coli 2011C-3493)

8e-155

1158) leuS
( YP_002401749.1 )

leucyl-tRNA synthetase

NC_011748
(Escherichia coli 55989)

8e-155

1159) leuS
( YP_007380535.1 )

leucyl-tRNA ligase

NC_020163
(Escherichia coli APEC O78)

8e-155

1160) leuS
( YP_002386097.1 )

leucyl-tRNA synthetase

NC_011741
(Escherichia coli IAI1)

8e-155

1161) EKO11_3224
( YP_005278871.1 )

leucyl-tRNA synthetase

NC_016902
(Escherichia coli KO11FL)

8e-155

1162) leuS
( YP_006166408.1 )

leucyl-tRNA synthetase

NC_017660
(Escherichia coli KO11FL)

8e-155

1163) leuS
( YP_008563832.1 )

leucyl-tRNA synthetase

NC_022364
(Escherichia coli LY180)

8e-155

1164) leuS
( YP_006123466.1 )

leucyl-tRNA synthetase

NC_017635
(Escherichia coli W)

8e-155

1165) leuS
( YP_006172146.1 )

leucyl-tRNA synthetase

NC_017664
(Escherichia coli W)

8e-155

1166) leuS
( YP_002383574.1 )

leucyl-tRNA synthetase

NC_011740
(Escherichia fergusonii ATCC 35469)

8e-155

1167) Afer_1322
( YP_003109921.1 )

leucyl-tRNA synthetase

NC_013124
(Acidimicrobium ferrooxidans DSM 10331)

8e-155

1168) Thivi_0986
( YP_006413146.1 )

leucyl-tRNA synthetase

NC_018012
(Thiocystis violascens DSM 198)

8e-155

1169) leuS
( YP_004009323.1 )

leucyl-tRNA synthetase

NC_014659
(Rhodococcus equi 103S)

9e-155

1170) Cwoe_2829
( YP_003394623.1 )

leucyl-tRNA synthetase

NC_013739
(Conexibacter woesei DSM 14684)

9e-155

1171) leuS
( YP_001457455.1 )

leucyl-tRNA synthetase

NC_009800
(Escherichia coli HS)

1e-154

1172) leuS
( YP_006137678.1 )

leucyl-tRNA synthetase

NC_017644
(Escherichia coli NA114)

1e-154

1173) leuS
( YP_003955187.1 )

leucyl-tRNA synthetase

NC_014623
(Stigmatella aurantiaca DW4/3-1)

1e-154

1174) Desde_3702
( YP_006431768.1 )

leucyl-tRNA synthetase

NC_018017
(Desulfitobacterium dehalogenans ATCC 51507)

2e-154

1175) leuS
( YP_947987.1 )

leucyl-tRNA synthetase

NC_008711
(Arthrobacter aurescens TC1)

2e-154

1176) leuS
( YP_668599.1 )

leucyl-tRNA synthetase

NC_008253
(Escherichia coli 536)

2e-154

1177) leuS
( YP_006104818.1 )

leucyl-tRNA synthetase

NC_017631
(Escherichia coli ABU 83972)

2e-154

1178) leuS
( YP_001461810.1 )

leucyl-tRNA synthetase

NC_009801
(Escherichia coli E24377A)

2e-154

1179) leuS
( YP_002396677.1 )

leucyl-tRNA synthetase

NC_011745
(Escherichia coli ED1a)

2e-154

1180) ECSF_0582
( YP_003348572.1 )

leucyl-tRNA synthetase

NC_013654
(Escherichia coli SE15)

2e-154

1181) leuS
( YP_688229.1 )

leucyl-tRNA synthetase

NC_008258
(Shigella flexneri 8401)

2e-154

1182) CYCME_0797
( YP_008373492.1 )

Leucyl-tRNA synthetase

NC_021917
(Cycloclasticus zancles 7-ME)

2e-154

1183) leuS
( YP_005844920.1 )

leucyl-tRNA synthetase

NC_017462
(Corynebacterium pseudotuberculosis 267)

3e-154

1184) leuS
( YP_005693529.1 )

leucyl-tRNA synthetase

NC_017306
(Corynebacterium pseudotuberculosis 42/02-A)

3e-154

1185) leuS
( YP_005684394.1 )

leucyl-tRNA synthetase

NC_017301
(Corynebacterium pseudotuberculosis C231)

3e-154

1186) leuS
( YP_005686489.1 )

leucyl-tRNA synthetase

NC_017303
(Corynebacterium pseudotuberculosis I19)

3e-154

1187) leuS
( YP_005376071.1 )

leucyl-tRNA synthetase

NC_017031
(Corynebacterium pseudotuberculosis P54B96)

3e-154

1188) leuS
( YP_005691479.1 )

leucyl-tRNA synthetase

NC_017305
(Corynebacterium pseudotuberculosis PAT10)

3e-154

1189) Btus_1210
( YP_003589081.1 )

leucyl-tRNA synthetase

NC_014098
(Kyrpidia tusciae DSM 2912)

3e-154

1190) Thebr_2003
( YP_004186905.1 )

leucyl-tRNA synthetase

NC_014964
(Thermoanaerobacter brockii Ako-1)

3e-154

1191) leuS
( YP_001665923.1 )

leucyl-tRNA synthetase

NC_010321
(Thermoanaerobacter pseudethanolicus ATCC 33223)

3e-154

1192) leuS
( YP_006142763.1 )

leucyl-tRNA synthetase

NC_017646
(Escherichia coli CE10)

3e-154

1193) leuS
( YP_002406643.1 )

leucyl-tRNA synthetase

NC_011750
(Escherichia coli IAI39)

3e-154

1194) leuS
( YP_001742758.1 )

leucyl-tRNA synthetase

NC_010498
(Escherichia coli SMS-3-5)

3e-154

1195) GNIT_2076
( YP_004872177.1 )

leucyl-tRNA synthetase

NC_016041
(Glaciecola nitratireducens FR1064)

3e-154

1196) leuS
( YP_005455221.1 )

leucyl-tRNA synthetase

NC_016822
(Shigella sonnei 53G)

3e-154

1197) leuS
( YP_309597.1 )

leucyl-tRNA synthetase

NC_007384
(Shigella sonnei Ss046)

3e-154

1198) Entcl_3155
( YP_003942685.1 )

leucyl-tRNA synthetase

NC_014618
(Enterobacter cloacae SCF1)

3e-154

1199) leuS
( YP_001550760.1 )

leucyl-tRNA synthetase

NC_009976
(Prochlorococcus marinus MIT 9211)

3e-154

1200) leuS
( YP_001475211.1 )

leucyl-tRNA synthetase

NC_009831
(Shewanella sediminis HAW-EB3)

3e-154

1201) leuS
( YP_460226.1 )

leucyl-tRNA synthetase

NC_007759
(Syntrophus aciditrophicus SB)

3e-154

1202) leuS
( YP_003538218.1 )

leucyl-tRNA synthetase

NC_013971
(Erwinia amylovora ATCC 49946)

4e-154

1203) leuS
( YP_003530482.1 )

leucyl-tRNA synthetase

NC_013961
(Erwinia amylovora CFBP1430)

4e-154

1204) HICON_04820
( YP_004137635.1 )

leucyl-tRNA synthetase

NC_014922
(Haemophilus influenzae F3047)

4e-154

1205) D781_1124
( YP_007343635.1 )

leucyl-tRNA synthetase

NC_020064
(Serratia marcescens FGI94)

4e-154

1206) Desdi_3025
( YP_007221826.1 )

leucyl-tRNA synthetase

NC_019903
(Desulfitobacterium dichloroeliminans LMG P-21439)

4e-154

1207) leuS
( YP_005124206.1 )

leucyl-tRNA synthetase

NC_016781
(Corynebacterium pseudotuberculosis 3/99-5)

5e-154

1208) leuS
( YP_003784451.1 )

leucyl-tRNA synthetase

NC_014329
(Corynebacterium pseudotuberculosis FRC41)

5e-154

1209) leuS
( YP_006717139.1 )

leucyl-tRNA ligase

NC_007498
(Pelobacter carbinolicus DSM 2380)

5e-154

1210) leuS
( YP_006662340.1 )

leucyl-tRNA synthetase

NC_018531
(Arthrobacter sp. Rue61a)

5e-154

1211) NT01EI_2936
( YP_002934325.1 )

leucyl-tRNA synthetase, putative

NC_012779
(Edwardsiella ictaluri 93-146)

5e-154

1212) leuS
( YP_005682304.1 )

leucyl-tRNA synthetase

NC_017300
(Corynebacterium pseudotuberculosis 1002)

6e-154

1213) leuS
( YP_003364286.1 )

leucyl-tRNA synthetase

NC_013716
(Citrobacter rodentium ICC168)

6e-154

1214) leuS
( YP_002411495.1 )

leucyl-tRNA synthetase

NC_011751
(Escherichia coli UMN026)

6e-154

1215) PARA_02330
( YP_004821934.1 )

leucyl-tRNA synthetase

NC_015964
(Haemophilus parainfluenzae T3T1)

6e-154

1216) Mmwyl1_2915
( YP_001341761.1 )

leucyl-tRNA synthetase

NC_009654
(Marinomonas sp. MWYL1)

6e-154

1217) leuS
( YP_827074.1 )

leucyl-tRNA synthetase

NC_008536
(Candidatus Solibacter usitatus Ellin6076)

6e-154

1218) leuS
( YP_436452.1 )

leucyl-tRNA synthetase

NC_007645
(Hahella chejuensis KCTC 2396)

6e-154

1219) leuS
( YP_005697557.1 )

leucyl-tRNA synthetase

NC_017308
(Corynebacterium pseudotuberculosis 1/06-A)

7e-154

1220) leuS
( YP_005304665.1 )

leucyl-tRNA synthetase

NC_016932
(Corynebacterium pseudotuberculosis 316)

7e-154

1221) leuS
( YP_005695591.1 )

leucyl-tRNA synthetase

NC_017307
(Corynebacterium pseudotuberculosis CIP 52.97)

7e-154

1222) leuS
( YP_006353621.1 )

leucyl-tRNA synthetase

NC_017945
(Corynebacterium pseudotuberculosis 258)

8e-154

1223) leuS
( YP_007324651.1 )

Leucine--tRNA ligase

NC_020055
(Desulfovibrio hydrothermalis DSM 14728)

8e-154

1224) leuS
( YP_006476697.1 )

leucyl-tRNA ligase

NC_018079
(Enterobacter cloacae SDM)

8e-154

1225) leuS
( YP_003255095.1 )

leucyl-tRNA synthetase

NC_013416
(Aggregatibacter actinomycetemcomitans D11S-1)

9e-154

1226) leuS
( YP_001502994.1 )

leucyl-tRNA synthetase

NC_009901
(Shewanella pealeana ATCC 700345)

9e-154

1227) leuS
( YP_006438128.1 )

leucyl-tRNA synthetase

NC_018019
(Corynebacterium pseudotuberculosis Cp162)

1e-153

1228) leuS
( YP_005472805.1 )

leucyl-tRNA synthetase

NC_017096
(Caldisericum exile AZM16c01)

1e-153

1229) Tthe_2364
( YP_003852914.1 )

leucyl-tRNA synthetase

NC_014410
(Thermoanaerobacterium thermosaccharolyticum DSM 571)

1e-153

1230) Thethe_02420
( YP_007299685.1 )

leucyl-tRNA synthetase

NC_019970
(Thermoanaerobacterium thermosaccharolyticum M0795)

1e-153

1231) D7S_01126
( YP_006286741.1 )

leucyl-tRNA synthetase

NC_017846
(Aggregatibacter actinomycetemcomitans D7S-1)

1e-153

1232) Despr_1832
( YP_004195272.1 )

leucyl-tRNA synthetase

NC_014972
(Desulfobulbus propionicus DSM 2032)

1e-153

1233) DGI_1902
( YP_008590855.1 )

putative leucyl-tRNA synthetase

NC_022444
(Desulfovibrio gigas ATCC 19364)

1e-153

1234) leuS
( YP_005818815.1 )

leucyl-tRNA synthetase

NC_017445
(Erwinia sp. Ejp617)

1e-153

1235) HIBPF13900
( YP_004135789.1 )

leucyl-tRNA synthetase

NC_014920
(Haemophilus influenzae F3031)

1e-153

1236) leuS
( YP_008543683.1 )

leucyl-tRNA synthetase

NC_022356
(Haemophilus influenzae KR494)

1e-153

1237) leuS
( YP_001009363.1 )

leucyl-tRNA synthetase

NC_008816
(Prochlorococcus marinus AS9601)

1e-153

1238) leuS
( YP_001675434.1 )

leucyl-tRNA synthetase

NC_010334
(Shewanella halifaxensis HAW-EB4)

1e-153

1239) leuS
( YP_246667.1 )

leucyl-tRNA synthetase

NC_007109
(Rickettsia felis URRWXCal2)

1e-153

1240) leuS
( YP_001571289.1 )

leucyl-tRNA synthetase

NC_010067
(Salmonella enterica RSK2980)

2e-153

1241) Dacet_1236
( YP_003503964.1 )

leucyl-tRNA synthetase

NC_013943
(Denitrovibrio acetiphilus DSM 12809)

9e-154

1242) leuS
( YP_006824735.1 )

leucyl-tRNA ligase

NC_018692
(Alteromonas macleodii Black Sea 11)

2e-153

1243) leuS
( YP_454483.1 )

leucyl-tRNA synthetase

NC_007712
(Sodalis glossinidius morsitans)

2e-153

1244) leuS
( YP_003740636.1 )

leucyl-tRNA synthetase

NC_014306
(Erwinia billingiae Eb661)

2e-153

1245) AciX9_2117
( YP_004217941.1 )

leucyl-tRNA synthetase

NC_015064
(Granulicella tundricola MP5ACTX9)

2e-153

1246) leuS
( YP_002488047.1 )

leucyl-tRNA synthetase

NC_011886
(Arthrobacter chlorophenolicus A6)

3e-153

1247) leuS
( YP_248619.1 )

leucyl-tRNA synthetase

NC_007146
(Haemophilus influenzae 86-028NP)

3e-153

1248) leuS
( YP_001678479.1 )

leucyl-tRNA synthetase

NC_010336
(Francisella philomiragia ATCC 25017)

3e-153

1249) Thet_0297
( YP_003903249.1 )

leucyl-tRNA synthetase

NC_014538
(Thermoanaerobacter sp. X513)

4e-153

1250) leuS
( YP_001661908.1 )

leucyl-tRNA synthetase

NC_010320
(Thermoanaerobacter sp. X514)

4e-153

1251) leuS
( YP_004203615.1 )

leucyl-tRNA synthetase

NC_014974
(Thermus scotoductus SA-01)

4e-153

1252) Theba_1985
( YP_006346871.1 )

leucyl-tRNA synthetase

NC_017934
(Mesotoga prima MesG1.Ag.4.2)

4e-153

1253) leuS
( YP_006819715.1 )

leucyl-tRNA synthetase

NC_018691
(Alcanivorax dieselolei B5)

5e-153

1254) leuS
( YP_003209638.1 )

leucyl-tRNA synthetase

NC_013282
(Cronobacter turicensis z3032)

5e-153

1255) DP2600
( YP_066336.1 )

leucyl-tRNA synthetase

NC_006138
(Desulfotalea psychrophila LSv54)

5e-153

1256) leuS
( YP_074273.1 )

leucyl-tRNA synthetase

NC_006177
(Symbiobacterium thermophilum IAM 14863)

5e-153

1257) leuS
( YP_411211.1 )

leucyl-tRNA synthetase

NC_007614
(Nitrosospira multiformis ATCC 25196)

6e-153

1258) PCC21_012110
( YP_006645867.1 )

leucyl-tRNA synthetase

NC_018525
(Pectobacterium carotovorum PCC21)

6e-153

1259) Tery_1704
( YP_721442.1 )

leucyl-tRNA synthetase

NC_008312
(Trichodesmium erythraeum IMS101)

1e-152

1260) leuS
( YP_001454059.1 )

leucyl-tRNA synthetase

NC_009792
(Citrobacter koseri ATCC BAA-895)

1e-152

1261) D782_3198
( YP_007341319.1 )

leucyl-tRNA synthetase

NC_020063
(Enterobacteriaceae bacterium FGI 57)

1e-152

1262) leuS
( YP_005828127.1 )

Leucyl-tRNA synthetase

NC_017451
(Haemophilus influenzae R2866)

1e-152

1263) leuS
( YP_004729455.1 )

leucyl-tRNA synthetase

NC_015761
(Salmonella bongori NCTC 12419)

1e-152

1264) leuS
( NP_360222.1 )

leucyl-tRNA synthetase

NC_003103
(Rickettsia conorii Malish 7)

1e-152

1265) Adeh_2727
( YP_465934.1 )

leucyl-tRNA synthetase

NC_007760
(Anaeromyxobacter dehalogenans 2CP-C)

6e-153

1266) leuS
( YP_001011285.1 )

leucyl-tRNA synthetase

NC_008817
(Prochlorococcus marinus MIT 9515)

7e-153

1267) leuS
( YP_006214532.1 )

leucyl-tRNA synthetase

NC_017730
(Corynebacterium pseudotuberculosis 31)

8e-153

1268) Tmath_0360
( YP_003676148.1 )

leucyl-tRNA synthetase

NC_014209
(Thermoanaerobacter mathranii A3)

8e-153

1269) leuS
( YP_007949991.1 )

leucyl-tRNA synthetase

NC_021191
(Actinoplanes sp. N902-109)

9e-153

1270) Thit_0284
( YP_003476165.1 )

leucyl-tRNA synthetase

NC_013921
(Thermoanaerobacter italicus Ab9)

9e-153

1271) A464_624
( YP_008321220.1 )

Leucyl-tRNA synthetase

NC_021870
(Salmonella bongori N268-08)

1e-152

1272) Smon_0349
( YP_003305710.1 )

leucyl-tRNA synthetase

NC_013515
(Streptobacillus moniliformis DSM 12112)

1e-152

1273) leuS
( YP_007466122.1 )

leucyl-tRNA ligase

NC_020302
(Corynebacterium halotolerans YIM 70093)

2e-152

1274) ECL_03054
( YP_003613539.1 )

leucyl-tRNA synthetase

NC_014121
(Enterobacter cloacae ATCC 13047)

2e-152

1275) leuS
( YP_006577780.1 )

leucyl-tRNA ligase

NC_018405
(Enterobacter cloacae ENHKU01)

2e-152

1276) leuS
( YP_001908271.1 )

leucyl-tRNA synthetase

NC_010694
(Erwinia tasmaniensis Et1/99)

2e-152

1277) leuS
( YP_008047011.1 )

leucyl-tRNA ligase

NC_021291
(Spiribacter salinus M19-40)

2e-152

1278) leuS
( YP_001291188.1 )

leucyl-tRNA synthetase

NC_009566
(Haemophilus influenzae PittEE)

3e-152

1279) leuS
( YP_005829839.1 )

leucyl-tRNA synthetase

NC_017452
(Haemophilus influenzae R2846)

3e-152

1280) leuS
( NP_439081.1 )

leucyl-tRNA synthetase

NC_000907
(Haemophilus influenzae Rd KW20)

3e-152

1281) leuS
( YP_001625087.1 )

leucyl-tRNA synthetase

NC_010168
(Renibacterium salmoninarum ATCC 33209)

3e-152

1282) ANH9381_0925
( YP_004948663.1 )

leucyl-tRNA synthetase

NC_016513
(Aggregatibacter actinomycetemcomitans ANH9381)

3e-152

1283) leuS
( YP_003930157.1 )

leucyl-tRNA synthetase

NC_014562
(Pantoea vagans C9-1)

3e-152

1284) leuS
( YP_251875.1 )

leucyl-tRNA synthetase

NC_007164
(Corynebacterium jeikeium K411)

4e-152

1285) leuS
( YP_006320304.1 )

leucyl-tRNA synthetase

NC_017910
(Escherichia blattae DSM 4481)

4e-152

1286) leuS
( YP_002225736.1 )

leucyl-tRNA synthetase

NC_011274
(Salmonella enterica 287/91)

4e-152

1287) HIB_10530
( YP_005179079.1 )

leucyl-tRNA synthetase

NC_016809
(Haemophilus influenzae 10810)

4e-152

1288) NT08PM_2253
( YP_006241105.1 )

leucyl-tRNA synthetase

NC_017764
(Pasteurella multocida 3480)

4e-152

1289) leuS
( YP_005177983.1 )

leucyl-tRNA synthetase

NC_016808
(Pasteurella multocida 36950)

4e-152

1290) leuS
( NP_246151.1 )

leucyl-tRNA synthetase

NC_002663
(Pasteurella multocida Pm70)

4e-152

1291) leuS
( YP_003260493.1 )

leucyl-tRNA synthetase

NC_013421
(Pectobacterium wasabiae WPP163)

4e-152

1292) SU5_01339
( YP_006086977.1 )

leucyl-tRNA synthetase

NC_017623
(Salmonella enterica B182)

5e-152

1293) leuS
( YP_005711749.1 )

leucyl-tRNA synthetase

NC_017317
(Corynebacterium ulcerans 809)

1e-151

1294) SBOV06001
( YP_008504478.1 )

hypothetical protein

NC_022241
(Salmonella enterica 3114)

1e-151

1295) leuS
( YP_008246600.1 )

leucyl-tRNA ligase

NC_021810
(Salmonella enterica 41578)

1e-151

1296) leuS
( YP_008309503.1 )

leucyl-tRNA synthetase

NC_021844
(Salmonella enterica CFSAN000189)

1e-151

1297) leuS
( YP_008259902.1 )

leucyl-tRNA synthetase

NC_021818
(Salmonella enterica CFSAN002050)

1e-151

1298) leuS
( YP_008249960.1 )

leucyl-tRNA synthetase

NC_021812
(Salmonella enterica CFSAN002069)

1e-151

1299) leuS
( YP_002113766.1 )

leucyl-tRNA synthetase

NC_011094
(Salmonella enterica CVM19633)

1e-151

1300) leuS
( YP_002636282.1 )

leucyl-tRNA synthetase

NC_012125
(Salmonella enterica RKS4594)

1e-151

1301) leuS
( YP_001589099.1 )

leucyl-tRNA synthetase

NC_010102
(Salmonella enterica SGSC4150; SPB7)

1e-151

1302) leuS
( YP_002039891.1 )

leucyl-tRNA synthetase

NC_011080
(Salmonella enterica SL254)

1e-151

1303) leuS
( YP_002044682.1 )

leucyl-tRNA synthetase

NC_011083
(Salmonella enterica SL476)

1e-151

1304) leuS
( YP_002145624.1 )

leucyl-tRNA synthetase

NC_011149
(Salmonella enterica SL483)

1e-151

1305) SN31241_16540
( YP_008359571.1 )

Leucyl-tRNA synthetase

NC_021902
(Salmonella enterica USMARC-S3124.1)

1e-151

1306) leuS
( YP_215665.1 )

leucyl-tRNA synthetase

NC_006905
(Salmonella enterica SC-B67)

6e-152

1307) leuS
( YP_001292851.1 )

leucyl-tRNA synthetase

NC_009567
(Haemophilus influenzae PittGG)

7e-152

1308) leuS
( YP_005396137.1 )

leucyl-tRNA synthetase

NC_017046
(Salmonella enterica 798)

8e-152

1309) leuS
( YP_008481911.1 )

leucyl-tRNA synthetase

NC_022221
(Salmonella enterica CDC1983-67)

8e-152

1310) leuS
( YP_005213454.1 )

leucyl-tRNA synthetase

NC_016831
(Salmonella enterica RKS5078)

8e-152

1311) leuS
( YP_005241594.1 )

leucyl-tRNA synthetase

NC_016857
(Salmonella enterica ST4/74)

8e-152

1312) leuS
( YP_004857647.1 )

leucyl-tRNA synthetase

NC_016012
(Candidatus Arthromitus sp. SFB-rat-Yit)

9e-152

1313) leuS
( YP_001438754.1 )

leucyl-tRNA synthetase

NC_009778
(Cronobacter sakazakii ATCC BAA-894)

9e-152

1314) leuS
( YP_006343842.1 )

leucyl-tRNA synthetase

NC_017933
(Cronobacter sakazakii ES15)

9e-152

1315) leuS
( YP_007441405.1 )

leucyl-tRNA ligase

NC_020260
(Cronobacter sakazakii Sp291)

9e-152

1316) DND132_1681
( YP_005167691.1 )

leucyl-tRNA synthetase

NC_016803
(Desulfovibrio desulfuricans ND132)

9e-152

1317) leuS
( YP_007471367.1 )

leucyl-tRNA ligase

NC_020307
(Salmonella enterica CFSAN001992)

9e-152

1318) W5S_3142
( YP_006284088.1 )

Leucyl-tRNA synthetase

NC_017845
(Pectobacterium sp. SCC3193)

9e-152

1319) leuS
( YP_008264898.1 )

leucyl-tRNA synthetase

NC_021820
(Salmonella enterica 08-1736)

1e-151

1320) STM14_0756
( YP_005236364.2 )

hypothetical protein

NC_016856
(Salmonella enterica 14028S)

1e-151

1321) leuS
( YP_008256112.1 )

leucyl-tRNA synthetase

NC_021814
(Salmonella enterica CFSAN001921)

1e-151

1322) leuS
( YP_002214637.1 )

leucyl-tRNA synthetase

NC_011205
(Salmonella enterica CT_02021853)

1e-151

1323) STMMW_07131
( YP_005231774.1 )

leucyl-tRNA synthetase

NC_016854
(Salmonella enterica D23580)

1e-151

1324) leuS
( NP_459640.1 )

leucyl-tRNA synthetase

NC_003197
(Salmonella enterica LT2)

1e-151

1325) leuS
( YP_005180558.1 )

leucyl-tRNA synthetase

NC_016810
(Salmonella enterica SL1344)

1e-151

1326) leuS
( YP_005246407.1 )

leucyl-tRNA synthetase

NC_016860
(Salmonella enterica T000240)

1e-151

1327) leuS
( YP_007903325.1 )

leucyl-tRNA ligase

NC_021151
(Salmonella enterica U288)

1e-151

1328) leuS
( YP_005251210.1 )

leucyl-tRNA synthetase

NC_016863
(Salmonella enterica UK-1)

1e-151

1329) PC1_1187
( YP_003016771.1 )

leucyl-tRNA synthetase

NC_012917
(Pectobacterium carotovorum PC1)

1e-151

1330) leuS
( YP_006571450.1 )

leucyl-tRNA synthetase

NC_018289
(Mycobacterium smegmatis MC2 155)

2e-151

1331) leuS
( YP_891113.1 )

leucyl-tRNA synthetase

NC_008596
(Mycobacterium smegmatis MC2 155)

2e-151

1332) leuS
( YP_006495717.1 )

leucyl-tRNA synthetase

NC_018101
(Corynebacterium ulcerans 0102)

2e-151

1333) leuS
( YP_004630908.1 )

leucyl-tRNA synthetase

NC_015683
(Corynebacterium ulcerans BR-AD22)

2e-151

1334) leuS
( YP_005364641.1 )

leucyl-tRNA synthetase

NC_017027
(Pasteurella multocida HN06)

2e-151

1335) leuS
( YP_002142777.1 )

leucyl-tRNA synthetase

NC_011147
(Salmonella enterica AKU12601)

2e-151

1336) leuS
( YP_151292.1 )

leucyl-tRNA synthetase

NC_006511
(Salmonella enterica ATCC 9150)

2e-151

1337) leuS
( YP_116175.1 )

leucyl-tRNA synthetase

NC_006360
(Mycoplasma hyopneumoniae 232)

3e-151

1338) TCCBUS3UF1_22230
( YP_005655333.1 )

leucyl-tRNA synthetase

NC_017278
(Thermus sp. CCB_US3_UF1)

3e-151

1339) STY0699
( NP_455224.1 )

leucyl-tRNA synthetase

NC_003198
(Salmonella enterica CT18)

3e-151

1340) STBHUCCB_23460
( YP_005217872.1 )

Leucyl-tRNA synthetase

NC_016832
(Salmonella enterica P-stx-12)

3e-151

1341) leuS
( YP_002242765.1 )

leucyl-tRNA synthetase

NC_011294
(Salmonella enterica P125109)

3e-151

1342) leuS
( NP_805962.1 )

leucyl-tRNA synthetase

NC_004631
(Salmonella enterica Ty2)

3e-151

1343) leuS
( YP_007926518.1 )

leucyl-tRNA synthetase

NC_021176
(Salmonella enterica Ty21a)

3e-151

1344) MELS_2130
( YP_004767174.1 )

leucyl-tRNA synthetase

NC_015873
(Megasphaera elsdenii DSM 20460)

3e-151

1345) leuS
( NP_794546.1 )

leucyl-tRNA synthetase

NC_004578
(Pseudomonas syringae DC3000)

3e-151

1346) LFE_0465
( YP_005468314.1 )

leucyl-tRNA synthetase

NC_017094
(Leptospirillum ferrooxidans C2-3)

4e-151

1347) Selsp_0877
( YP_004413301.1 )

leucyl-tRNA synthetase

NC_015437
(Selenomonas sputigena ATCC 35185)

5e-151

1348) leuS
( YP_005175625.1 )

leucyl-tRNA synthetase

NC_016807
(Mycoplasma pneumoniae 309)

7e-151

1349) leuS
( YP_005881396.1 )

leucyl-tRNA synthetase

NC_017504
(Mycoplasma pneumoniae FH)

7e-151

1350) leuS
( YP_001095054.1 )

leucyl-tRNA synthetase

NC_009092
(Shewanella loihica PV-4)

8e-151

1351) TOPB45_1433
( YP_004628441.1 )

leucyl-tRNA synthetase

NC_015682
(Thermodesulfobacterium geofontis OPB45)

1e-150

1352) leuS
( NP_110072.1 )

leucyl-tRNA synthetase

NC_000912
(Mycoplasma pneumoniae M129)

1e-150

1353) leuS
( YP_003558149.1 )

leucyl-tRNA synthetase

NC_014012
(Shewanella violacea DSS12)

1e-150

1354) leuS
( YP_001671067.1 )

leucyl-tRNA synthetase

NC_010322
(Pseudomonas putida GB-1)

2e-150

1355) C985_0387
( YP_007347979.1 )

Leucyl-tRNA synthetase

NC_020076
(Mycoplasma pneumoniae M129-B7)

9e-151

1356) PP1Y_AT802
( YP_004532879.1 )

leucyl-tRNA synthetase

NC_015580
(Novosphingobium sp. PP1Y)

4e-150

1357) leuS
( YP_007042599.1 )

Leucyl-tRNA synthetase

NC_019673
(Saccharothrix espanaensis DSM 44229)

5e-150

1358) leuS
( YP_006639553.1 )

leucine--tRNA ligase

NC_018524
(Nocardiopsis alba ATCC BAA-2165)

5e-150

1359) leuS
( YP_005163734.1 )

leucyl-tRNA synthetase

NC_016801
(Corynebacterium diphtheriae C7 (beta))

8e-150

1360) leuS
( YP_002835998.1 )

leucyl-tRNA synthetase

NC_012590
(Corynebacterium aurimucosum ATCC 700975)

1e-149

1361) leuS
( YP_005126460.1 )

leucyl-tRNA synthetase

NC_016782
(Corynebacterium diphtheriae 241)

1e-149

1362) leuS
( YP_005159036.1 )

leucyl-tRNA synthetase

NC_016799
(Corynebacterium diphtheriae 31A)

1e-149

1363) leuS
( YP_005136995.1 )

leucyl-tRNA synthetase

NC_016786
(Corynebacterium diphtheriae HC01)

1e-149

1364) leuS
( YP_005165966.1 )

leucyl-tRNA synthetase

NC_016802
(Corynebacterium diphtheriae HC02)

1e-149

1365) leuS
( YP_008456297.1 )

leucyl-tRNA ligase

NC_022115
(Rhodococcus erythropolis CCM2595)

1e-149

1366) leuS
( YP_002769444.1 )

leucyl-tRNA synthetase

NC_012490
(Rhodococcus erythropolis PR4)

1e-149

1367) leuS
( YP_004467231.1 )

leucyl-tRNA synthetase

NC_015554
(Alteromonas sp. SN2)

1e-149

1368) Trad_2121
( YP_003705777.1 )

leucyl-tRNA synthetase

NC_014221
(Truepera radiovictrix DSM 17093)

8e-150

1369) leuS
( YP_001003711.1 )

leucyl-tRNA synthetase

NC_008789
(Halorhodospira halophila SL1)

8e-150

1370) leuS
( YP_004679964.1 )

leucyl-tRNA synthetase

NC_015722
(Candidatus Midichloria mitochondrii IricVA)

8e-150

1371) leuS
( YP_005139256.1 )

leucyl-tRNA synthetase

NC_016787
(Corynebacterium diphtheriae HC03)

9e-150

1372) Nwat_0451
( YP_003759737.1 )

leucyl-tRNA synthetase

NC_014315
(Nitrosococcus watsonii C-113)

1e-149

1373) leuS
( YP_005128673.1 )

leucyl-tRNA synthetase

NC_016783
(Corynebacterium diphtheriae INCA 402)

2e-149

1374) leuS
( YP_005143851.1 )

leucyl-tRNA synthetase

NC_016789
(Corynebacterium diphtheriae PW8)

2e-149

1375) leuS
( YP_005134741.1 )

leucyl-tRNA synthetase

NC_016785
(Corynebacterium diphtheriae CDCE 8392)

2e-149

1376) leuS
( YP_003075179.1 )

leucyl-tRNA synthetase

NC_012997
(Teredinibacter turnerae T7901)

2e-149

1377) AnaeK_2819
( YP_002135172.1 )

leucyl-tRNA synthetase

NC_011145
(Anaeromyxobacter sp. K)

2e-149

1378) leuS
( YP_004951084.1 )

leucyl-tRNA synthetase

NC_016514
(Enterobacter cloacae EcWSU1)

2e-149

1379) OOM_1545
( YP_006317410.1 )

leucyl-tRNA synthetase

NC_017909
(Francisella noatunensis Toba 04)

2e-149

1380) leuS
( YP_005141533.1 )

leucyl-tRNA synthetase

NC_016788
(Corynebacterium diphtheriae HC04)

3e-149

1381) leuS
( YP_005146046.1 )

leucyl-tRNA synthetase

NC_016790
(Corynebacterium diphtheriae VA01)

3e-149

1382) Mspyr1_53210
( YP_004079680.1 )

leucyl-tRNA synthetase

NC_014814
(Mycobacterium gilvum Spyr1)

3e-149

1383) leuS
( YP_001334354.1 )

leucyl-tRNA synthetase

NC_009648
(Klebsiella pneumoniae subsp. pneumoniae MGH 78578)

3e-149

1384) Noc_2665
( YP_344648.1 )

leucyl-tRNA synthetase

NC_007484
(Nitrosococcus oceani ATCC 19707)

3e-149

1385) leuS
( YP_002894002.1 )

leucyl-tRNA synthetase

NC_012691
(Tolumonas auensis DSM 9187)

3e-149

1386) leuS
( YP_879355.1 )

leucyl-tRNA synthetase

NC_008595
(Mycobacterium avium 104)

4e-149

1387) leuS
( NP_958982.1 )

leucyl-tRNA synthetase

NC_002944
(Mycobacterium avium K-10)

4e-149

1388) MAP4_3827
( YP_007973586.1 )

leucyl-tRNA synthetase LeuS

NC_021200
(Mycobacterium avium MAP4)

4e-149

1389) leuS
( NP_940621.1 )

leucyl-tRNA synthetase

NC_002935
(Corynebacterium diphtheriae NCTC13129)

4e-149

1390) A79E_3565
( YP_006637345.1 )

leucyl-tRNA synthetase

NC_018522
(Klebsiella pneumoniae 1084)

4e-149

1391) KPHS_15130
( YP_005225813.1 )

leucyl-tRNA synthetase

NC_016845
(Klebsiella pneumoniae HS11286)

4e-149

1392) N559_3648
( YP_008426570.1 )

leucyl-tRNA synthetase

NC_022082
(Klebsiella pneumoniae JM45)

4e-149

1393) leuS
( YP_002918443.1 )

leucyl-tRNA synthetase

NC_012731
(Klebsiella pneumoniae NTUH-K2044)

4e-149

1394) leuS
( YP_005161398.1 )

leucyl-tRNA synthetase

NC_016800
(Corynebacterium diphtheriae BH8)

5e-149

1395) leuS
( YP_002874908.1 )

leucyl-tRNA synthetase

NC_012660
(Pseudomonas fluorescens SBW25)

5e-149

1396) Mmc1_0432
( YP_864363.1 )

leucyl-tRNA synthetase

NC_008576
(Magnetococcus marinus MC-1)

5e-149

1397) leuS
( YP_002239703.1 )

leucyl-tRNA synthetase

NC_011283
(Klebsiella pneumoniae 342)

1e-148

1398) Kvar_3692
( YP_003440604.1 )

leucyl-tRNA synthetase

NC_013850
(Klebsiella variicola At-22)

1e-148

1399) Entas_1156
( YP_004827687.1 )

leucyl-tRNA synthetase

NC_015968
(Enterobacter asburiae LF7a)

1e-148

1400) ENC_20680
( YP_007845783.1 )

leucyl-tRNA synthetase

NC_021046
(Enterobacter cloacae NCTC 9394)

1e-148

1401) leuS
( NP_953258.1 )

leucyl-tRNA ligase

NC_002939
(Geobacter sulfurreducens PCA)

6e-149

1402) leuS
( YP_007365237.1 )

leucyl-tRNA synthetase

NC_020127
(Lawsonia intracellularis N343)

6e-149

1403) leuS
( YP_594530.1 )

leucyl-tRNA synthetase

NC_008011
(Lawsonia intracellularis PHE/MN1-00)

6e-149

1404) leuS
( YP_005953732.1 )

leucyl-tRNA synthetase

NC_017540
(Klebsiella pneumoniae KCTC 2242)

7e-149

1405) leuS
( YP_002780635.1 )

leucyl-tRNA synthetase

NC_012522
(Rhodococcus opacus B4)

9e-149

1406) leuS
( YP_006891116.1 )

leucyl-tRNA synthetase

NC_017454
(Geobacter sulfurreducens KN400)

1e-148

1407) leuS
( YP_872530.1 )

leucyl-tRNA synthetase

NC_008578
(Acidothermus cellulolyticus 11B)

1e-148

1408) leuS
( YP_007992875.1 )

hypothetical protein

NC_021232
(Klebsiella pneumoniae SB3432)

1e-148

1409) MU9_1349
( YP_007504768.1 )

Leucyl-tRNA synthetase

NC_020418
(Morganella morganii KT)

1e-148

1410) leuS
( YP_001091194.1 )

leucyl-tRNA synthetase

NC_009091
(Prochlorococcus marinus MIT 9301)

1e-148

1411) leuS
( YP_007874574.1 )

leucyl-tRNA ligase

NC_021066
(Raoultella ornithinolytica B6)

1e-148

1412) leuS
( YP_003135724.1 )

leucyl-tRNA synthetase

NC_013159
(Saccharomonospora viridis DSM 43017)

2e-148

1413) leuS
( YP_001269973.1 )

leucyl-tRNA synthetase

NC_009512
(Pseudomonas putida F1)

2e-148

1414) leuS
( YP_004706660.1 )

leucyl-tRNA synthetase

NC_015735
(Candidatus Moranella endobia PCIT)

3e-148

1415) leuS
( YP_003296684.1 )

leucyl-tRNA synthetase

NC_013508
(Edwardsiella tarda EIB202)

3e-148

1416) ETAF_2377
( YP_005699972.1 )

leucyl-tRNA synthetase

NC_017309
(Edwardsiella tarda FL6-60)

3e-148

1417) Theos_1861
( YP_006972974.1 )

leucyl-tRNA synthetase

NC_019386
(Thermus oshimai JL-2)

4e-148

1418) leuS
( YP_007864447.1 )

Leucyl-tRNA synthetase

NC_021057
(Candidatus Moranella endobia PCVAL)

4e-148

1419) leuS
( YP_005368633.1 )

leucyl-tRNA synthetase

NC_017030
(Corallococcus coralloides DSM 2259)

4e-148

1420) leuS
( YP_007630016.1 )

leucyl-tRNA ligase

NC_020796
(Edwardsiella tarda C07-087)

4e-148

1421) T1E_4712
( YP_006535333.1 )

Leucyl-tRNA synthetase

NC_018220
(Pseudomonas putida DOT-T1E)

4e-148

1422) YSA_03698
( YP_006385881.1 )

leucyl-tRNA synthetase

NC_017986
(Pseudomonas putida ND6)

4e-148

1423) KTR9_4724
( YP_006671509.1 )

Leucyl-tRNA synthetase

NC_018581
(Gordonia sp. KTR9)

5e-148

1424) TK90_2132
( YP_003461358.1 )

leucyl-tRNA synthetase

NC_013889
(Thioalkalivibrio sp. K90mix)

5e-148

1425) Metme_3062
( YP_004513939.1 )

leucyl-tRNA synthetase

NC_015572
(Methylomonas methanica MC09)

5e-148

1426) Mycch_5305
( YP_006455668.1 )

leucyl-tRNA synthetase

NC_018027
(Mycobacterium chubuense NBB4)

7e-148

1427) leuS
( YP_003041986.1 )

leucyl-tRNA synthetase

NC_012962
(Photorhabdus asymbiotica ATCC 43949)

7e-148

1428) leuS
( YP_005932344.1 )

LeuS protein

NC_017530
(Pseudomonas putida BIRD-1)

7e-148

1429) leuS
( NP_746899.1 )

leucyl-tRNA synthetase

NC_002947
(Pseudomonas putida KT2440)

7e-148

1430) leuS
( YP_007564910.1 )

leucyl-tRNA synthetase

NC_020520
(Ilumatobacter coccineum YM16-304)

1e-147

1431) leuS
( YP_604038.1 )

leucyl-tRNA synthetase

NC_008025
(Deinococcus geothermalis DSM 11300)

1e-147

1432) Pat9b_1072
( YP_004114950.1 )

leucyl-tRNA synthetase

NC_014837
(Pantoea sp. At-9b)

2e-147

1433) leuS
( YP_003810114.1 )

leucyl-tRNA synthetase

NC_014366
(gamma proteobacterium HdN1)

2e-147

1434) leuS
( YP_003058406.1 )

leucyl-tRNA synthetase

NC_012982
(Hirschia baltica ATCC 59814)

2e-147

1435) Nhal_0537
( YP_003526108.1 )

leucyl-tRNA synthetase

NC_013960
(Nitrosococcus halophilus Nc 4)

3e-147

1436) A2cp1_2911
( YP_002493314.1 )

leucyl-tRNA synthetase

NC_011891
(Anaeromyxobacter dehalogenans 2CP-1)

3e-147

1437) Snas_4914
( YP_003513648.1 )

leucyl-tRNA synthetase

NC_013947
(Stackebrandtia nassauensis DSM 44728)

4e-147

1438) leuS
( YP_008017067.1 )

leucyl-tRNA synthetase

NC_021252
(Amycolatopsis orientalis HCCB10007)

4e-147

1439) leuS
( YP_006601303.1 )

leucyl-tRNA ligase

NC_018498
(Mycoplasma genitalium M2288)

4e-147

1440) leuS
( YP_006600295.1 )

leucyl-tRNA ligase

NC_018496
(Mycoplasma genitalium M6282)

4e-147

1441) leuS
( YP_002249023.1 )

leucyl-tRNA synthetase

NC_011296
(Thermodesulfovibrio yellowstonii DSM 11347)

5e-147

1442) Cfla_2234
( YP_003637324.1 )

leucyl-tRNA synthetase

NC_014151
(Cellulomonas flavigena DSM 20109)

6e-147

1443) leuS
( YP_002786118.1 )

leucyl-tRNA synthetase

NC_012526
(Deinococcus deserti VCD115)

7e-147

1444) leuS
( YP_002957307.1 )

leucyl-tRNA synthetase

NC_012803
(Micrococcus luteus NCTC 2665)

7e-147

1445) leuS
( YP_008465521.1 )

leucyl-tRNA synthetase

NC_022116
(Amycolatopsis mediterranei RB)

1e-146

1446) leuS
( YP_005537490.1 )

leucyl-tRNA synthetase

NC_017186
(Amycolatopsis mediterranei S699)

1e-146

1447) leuS
( YP_006555668.1 )

leucyl-tRNA synthetase

NC_018266
(Amycolatopsis mediterranei S699)

1e-146

1448) leuS
( YP_003771420.1 )

leucyl-tRNA synthetase

NC_014318
(Amycolatopsis mediterranei U32)

1e-146

1449) ML5_3818
( YP_004083480.1 )

leucyl-tRNA synthetase

NC_014815
(Micromonospora sp. L5)

1e-146

1450) leuS
( YP_001160037.1 )

leucyl-tRNA synthetase

NC_009380
(Salinispora tropica CNB-440)

1e-146

1451) leuS
( YP_632907.1 )

leucyl-tRNA synthetase

NC_008095
(Myxococcus xanthus DK 1622)

1e-146

1452) leuS
( YP_006217591.1 )

leucyl-tRNA synthetase

NC_017731
(Providencia stuartii MRSN 2154)

1e-146

1453) Mar181_1146
( YP_004481113.1 )

leucyl-tRNA synthetase

NC_015559
(Marinomonas posidonica IVIA-Po-181)

8e-147

1454) leuS
( YP_006599807.1 )

leucyl-tRNA ligase

NC_018495
(Mycoplasma genitalium M2321)

9e-147

1455) leuS
( YP_006600799.1 )

leucyl-tRNA ligase

NC_018497
(Mycoplasma genitalium M6320)

9e-147

1456) Deipe_0136
( YP_007179510.1 )

leucyl-tRNA synthetase

NC_019793
(Deinococcus peraridilitoris DSM 19664)

1e-146

1457) leuS
( YP_703583.1 )

leucyl-tRNA synthetase

NC_008268
(Rhodococcus jostii RHA1)

2e-146

1458) leuS
( YP_001952352.1 )

leucyl-tRNA synthetase

NC_010814
(Geobacter lovleyi SZ)

2e-146

1459) leuS
( NP_072933.1 )

leucyl-tRNA synthetase

NC_000908
(Mycoplasma genitalium G37)

2e-146

1460) MYSTI_05203
( YP_007362168.1 )

leucyl-tRNA synthetase

NC_020126
(Myxococcus stipitatus DSM 14675)

2e-146

1461) Psest_0525
( YP_007238762.1 )

leucyl-tRNA synthetase

NC_019936
(Pseudomonas stutzeri RCH2)

2e-146

1462) leuS
( YP_537481.1 )

leucyl-tRNA synthetase

NC_007940
(Rickettsia bellii RML369-C)

2e-146

1463) Gbro_4829
( YP_003275835.1 )

leucyl-tRNA synthetase

NC_013441
(Gordonia bronchialis DSM 43247)

3e-146

1464) leuS
( YP_001222289.1 )

leucyl-tRNA synthetase

NC_009480
(Clavibacter michiganensis NCPPB 382)

3e-146

1465) leuS
( YP_002907332.1 )

leucyl-tRNA synthetase

NC_012704
(Corynebacterium kroppenstedtii DSM 44385)

4e-146

1466) leuS
( YP_923081.1 )

leucyl-tRNA synthetase

NC_008699
(Nocardioides sp. JS614)

4e-146

1467) leuS
( YP_008166862.1 )

leucyl-tRNA ligase

NC_021663
(Corynebacterium terpenotabidum Y-11)

1e-145

1468) Micau_4485
( YP_003837574.1 )

leucyl-tRNA synthetase

NC_014391
(Micromonospora aurantiaca ATCC 27029)

1e-145

1469) leuS
( YP_007262755.1 )

Leucyl-tRNA synthetase

NC_019951
(Mycobacterium canettii CIPT 140070010)

1e-145

1470) leuS
( YP_007266681.1 )

Leucyl-tRNA synthetase

NC_019952
(Mycobacterium canettii CIPT 140070017)

1e-145

1471) Desti_3834
( YP_006448740.1 )

leucyl-tRNA synthetase

NC_018025
(Desulfomonile tiedjei DSM 6799)

1e-145

1472) Psed_6668
( YP_004336609.1 )

leucyl-tRNA synthetase

NC_015312
(Pseudonocardia dioxanivorans CB1190)

7e-146

1473) leuS
( YP_004173700.1 )

leucyl-tRNA synthetase

NC_014960
(Anaerolinea thermophila UNI-1)

1e-145

1474) A225_1672
( YP_006497416.1 )

leucyl-tRNA synthetase

NC_018106
(Klebsiella oxytoca E718)

1e-145

1475) leuS
( YP_005018816.1 )

leucyl-tRNA synthetase

NC_016612
(Klebsiella oxytoca KCTC 1686)

1e-145

1476) leuS
( NP_875339.1 )

leucyl-tRNA synthetase

NC_005042
(Prochlorococcus marinus CCMP1375)

1e-145

1477) leuS
( YP_004721766.1 )

leucyl-tRNA synthetase

NC_015758
(Mycobacterium africanum GM041182)

2e-145

1478) leuS
( NP_853711.1 )

leucyl-tRNA synthetase

NC_002945
(Mycobacterium bovis AF2122/97)

2e-145

1479) leuS
( YP_976174.1 )

leucyl-tRNA synthetase

NC_008769
(Mycobacterium bovis BCG Pasteur 1173P2)

2e-145

1480) K60_000450
( YP_007429103.1 )

leucyl-tRNA synthetase

NC_020245
(Mycobacterium bovis Korea 1168P)

2e-145

1481) leuS
( YP_005169517.1 )

leucyl-tRNA synthetase

NC_016804
(Mycobacterium bovis Mexico)

2e-145

1482) leuS
( YP_002643091.1 )

leucyl-tRNA synthetase

NC_012207
(Mycobacterium bovis Tokyo 172)

2e-145

1483) leuS
( YP_004743526.1 )

putative leucyl-tRNA synthetase LEUS

NC_015848
(Mycobacterium canettii CIPT 140010059)

2e-145

1484) leuS
( YP_007258762.1 )

Leucyl-tRNA synthetase

NC_019950
(Mycobacterium canettii CIPT 140060008)

2e-145

1485) leuS
( YP_007285929.1 )

Leucyl-tRNA synthetase

NC_019965
(Mycobacterium canettii CIPT 140070008)

2e-145

1486) leuS
( YP_001132125.1 )

leucyl-tRNA synthetase

NC_009338
(Mycobacterium gilvum PYR-GCK)

2e-145

1487) MT7199_0041
( YP_007349779.1 )

putative LEUCYL-tRNA SYNTHETASE LEUS (LEUCINE-tRNA LIGASE) (LEURS)

NC_020089
(Mycobacterium tuberculosis 7199-99)

2e-145

1488) leuS
( YP_007959928.1 )

leucyl-tRNA ligase

NC_021193
(Mycobacterium tuberculosis CAS/NITR204)

2e-145

1489) leuS
( NP_334455.1 )

leucyl-tRNA synthetase

NC_002755
(Mycobacterium tuberculosis CDC1551)

2e-145

1490) leuS
( YP_005915110.1 )

leucyl-tRNA synthetase

NC_017524
(Mycobacterium tuberculosis CTRI-2)

2e-145

1491) M943_00240
( YP_008224140.1 )

leucyl-tRNA synthetase

NC_021740
(Mycobacterium tuberculosis EAI5)

2e-145

1492) leuS
( YP_007963889.1 )

leucyl-tRNA ligase

NC_021194
(Mycobacterium tuberculosis EAI5/NITR206)

2e-145

1493) leuS
( YP_007608543.1 )

leucyl-tRNA synthetase

NC_020559
(Mycobacterium tuberculosis Erdman (ATCC35801))

2e-145

1494) leuS
( YP_001285985.1 )

leucyl-tRNA synthetase

NC_009565
(Mycobacterium tuberculosis F11)

2e-145

1495) leuS
( YP_001281324.1 )

leucyl-tRNA synthetase

NC_009525
(Mycobacterium tuberculosis H37Ra)

2e-145

1496) leuS
( NP_214555.1 )

Probable leucyl-tRNA synthetase LeuS (leucine--tRNA ligase) (LEURS)

NC_000962
(Mycobacterium tuberculosis H37Rv)

2e-145

1497) RVBD_0041
( YP_006513355.1 )

leucyl-tRNA synthetase

NC_018143
(Mycobacterium tuberculosis H37Rv)

2e-145

1498) TBHG_00041
( YP_002159343.1 )

leucyl-tRNA synthetase LeuS

NC_022350
(Mycobacterium tuberculosis Haarlem)

2e-145

1499) leuS
( YP_003029957.1 )

leucyl-tRNA synthetase

NC_012943
(Mycobacterium tuberculosis KZN 1435)

2e-145

1500) TBSG_00040
( YP_005098508.1 )

leucyl-tRNA synthetase leuS

NC_016768
(Mycobacterium tuberculosis KZN 4207)

2e-145

1501) TBXG_000040
( YP_006471494.1 )

leucyl-tRNA synthetase leuS

NC_018078
(Mycobacterium tuberculosis KZN 605)

2e-145

1502) leuS
( YP_005358791.1 )

leucyl-tRNA synthetase

NC_017026
(Mycobacterium tuberculosis RGTB327)

2e-145

1503) leuS
( YP_005921407.1 )

leucyl-tRNA synthetase

NC_017528
(Mycobacterium tuberculosis RGTB423)

2e-145

1504) leuS
( YP_005306390.1 )

hypothetical protein

NC_016934
(Mycobacterium tuberculosis UT205)

2e-145

1505) leuS
( YP_006326103.1 )

leucyl-tRNA synthetase

NC_017911
(Pseudomonas fluorescens A506)

3e-145

1506) leuS
( YP_005940449.1 )

leucyl-tRNA synthetase

NC_017532
(Pseudomonas stutzeri DSM 4166)

3e-145

1507) leuS
( YP_005933327.1 )

leucyl-tRNA synthetase

NC_017531
(Pantoea ananatis AJ13355)

4e-145

1508) leuS
( YP_005196589.1 )

leucyl-tRNA synthetase

NC_016816
(Pantoea ananatis LMG 5342)

4e-145

1509) PAGR_g3028
( YP_005993744.1 )

leucyl-tRNA synthetase

NC_017554
(Pantoea ananatis PA13)

4e-145

1510) leuS
( YP_237420.1 )

leucyl-tRNA synthetase

NC_007005
(Pseudomonas syringae B728a)

4e-145

1511) leuS
( YP_007852929.1 )

leucyl-tRNA ligase

NC_021054
(Mycobacterium tuberculosis Beijing/NITR203)

5e-145

1512) CCDC5079_0038
( YP_005911461.1 )

leucyl-tRNA synthetase

NC_017523
(Mycobacterium tuberculosis CCDC5079)

5e-145

1513) leuS
( YP_008004882.1 )

leucyl-tRNA synthetase

NC_021251
(Mycobacterium tuberculosis CCDC5079)

5e-145

1514) CCDC5180_0039
( YP_005907871.1 )

leucyl-tRNA synthetase

NC_017522
(Mycobacterium tuberculosis CCDC5180)

5e-145

1515) leuS2
( YP_007031765.1 )

leucyl-tRNA synthetase

NC_019670
(Pseudomonas sp. UW4)

5e-145

1516) swp_3914
( YP_002313176.1 )

Leucyl-tRNA synthetase, class Ia

NC_011566
(Shewanella piezotolerans WP3)

5e-145

1517) leuS
( YP_001174233.1 )

leucyl-tRNA synthetase

NC_009434
(Pseudomonas stutzeri A1501)

5e-145

1518) Sfum_2084
( YP_846202.1 )

leucyl-tRNA synthetase

NC_008554
(Syntrophobacter fumaroxidans MPOB)

5e-145

1519) APP7_0931
( YP_001968725.1 )

leucyl-tRNA synthetase

NC_010939
(Actinobacillus pleuropneumoniae AP76)

1e-144

1520) Kole_0173
( YP_002939903.1 )

leucyl-tRNA synthetase

NC_012785
(Kosmotoga olearia TBF 19.5.1)

1e-144

1521) leuS
( YP_004716092.1 )

Leucyl-tRNA synthetase

NC_015740
(Pseudomonas stutzeri ATCC 17588)

1e-144

1522) leuS
( NP_893007.1 )

leucyl-tRNA synthetase

NC_005072
(Prochlorococcus marinus CCMP1986)

2e-144

1523) OEM_00480
( YP_008185914.1 )

leucyl-tRNA synthetase

NC_021715
(Mycobacterium yongonense 05-1390)

2e-144

1524) Hipma_1167
( YP_004340188.1 )

leucyl-tRNA synthetase

NC_015318
(Hippea maritima DSM 10411)

2e-144

1525) Deba_1412
( YP_003807374.1 )

leucyl-tRNA synthetase

NC_014365
(Desulfarculus baarsii DSM 2075)

2e-144

1526) Q7A_1275
( YP_006295757.1 )

leucyl-tRNA synthetase

NC_017857
(Methylophaga sp. JAM1)

2e-144

1527) leuS
( YP_003519425.1 )

LeuS

NC_013956
(Pantoea ananatis LMG 20103)

2e-144

1528) leuS
( YP_004495792.1 )

leucyl-tRNA synthetase

NC_015564
(Amycolicicoccus subflavus DQS3-9A1)

3e-144

1529) leuS
( YP_262507.1 )

leucyl-tRNA synthetase

NC_004129
(Pseudomonas protegens Pf-5)

3e-144

1530) leuS
( YP_008002651.1 )

leucyl-tRNA synthetase LeuS

NC_021237
(Pseudomonas fluorescens CHA0)

3e-144

1531) MIP_00064
( YP_006727116.1 )

leucyl-tRNA synthetase

NC_018612
(Mycobacterium indicus pranii MTCC 9506)

4e-144

1532) leuS
( YP_008110149.1 )

leucyl-tRNA synthetase

NC_021500
(Enterobacter sp. R4-368)

4e-144

1533) OCU_00490
( YP_005335590.1 )

leucyl-tRNA synthetase

NC_016946
(Mycobacterium intracellulare ATCC 13950)

4e-144

1534) leuS
( YP_005285357.1 )

leucyl-tRNA synthetase

NC_016906
(Gordonia polyisoprenivorans VH2)

5e-144

1535) OCQ_00480
( YP_005345882.1 )

leucyl-tRNA synthetase

NC_016948
(Mycobacterium intracellulare MOTT-64)

5e-144

1536) leuS
( YP_006303761.1 )

leucyl-tRNA synthetase

NC_017904
(Mycobacterium sp. MOTT36Y)

5e-144

1537) PSEBR_a4951
( YP_004356377.1 )

leucine--tRNA ligase

NC_015379
(Pseudomonas brassicacearum NFM421)

5e-144

1538) leuS
( YP_005210520.1 )

LeuS protein

NC_016830
(Pseudomonas fluorescens F113)

7e-144

1539) leuS
( YP_007399047.1 )

leucyl-tRNA ligase

NC_020209
(Pseudomonas poae RE*1-1-14)

7e-144

1540) Mycsm_06489
( YP_007296035.1 )

leucyl-tRNA synthetase

NC_019966
(Mycobacterium smegmatis JS623)

9e-144

1541) Deipr_0908
( YP_004255681.1 )

leucyl-tRNA synthetase

NC_015161
(Deinococcus proteolyticus MRP)

1e-143

1542) leuS
( YP_001109454.1 )

leucyl-tRNA synthetase

NC_009142
(Saccharopolyspora erythraea NRRL 2338)

2e-143

1543) ST548_p5866
( YP_007388732.1 )

Leucyl-tRNA synthetase

NC_020181
(Enterobacter aerogenes EA1509E)

2e-143

1544) leuS
( YP_004592972.1 )

leucyl-tRNA synthetase

NC_015663
(Enterobacter aerogenes KCTC 2190)

2e-143

1545) leuS
( YP_008101145.1 )

leucyl-tRNA synthetase

NC_021499
(Pseudomonas resinovorans NBRC 106553)

2e-143

1546) leuS
( YP_002986725.1 )

leucyl-tRNA synthetase

NC_012880
(Dickeya dadantii Ech703)

9e-144

1547) leuS
( YP_008115898.1 )

leucyl-tRNA synthetase

NC_021505
(Pseudomonas putida NBRC 14164)

9e-144

1548) Rxyl_3202
( YP_645919.1 )

leucyl-tRNA synthetase

NC_008148
(Rubrobacter xylanophilus DSM 9941)

2e-143

1549) OCO_00480
( YP_005340733.1 )

leucyl-tRNA synthetase

NC_016947
(Mycobacterium intracellulare MOTT-02)

3e-143

1550) leuS
( YP_005266787.1 )

Leucyl-tRNA synthetase (Leucine--tRNA ligase) (LeuRS)

NC_016887
(Nocardia cyriacigeorgica GUH-2)

3e-143

1551) leuS
( YP_002881748.1 )

leucyl-tRNA synthetase

NC_012669
(Beutenbergia cavernae DSM 12333)

3e-143

1552) GPA_10270
( YP_007802149.1 )

leucyl-tRNA synthetase

NC_021021
(Gordonibacter pamelaeae 7-10-1-bT)

3e-143

1553) leuS
( YP_008097559.1 )

leucyl-tRNA synthetase

NC_021491
(Pseudomonas putida H8234)

5e-143

1554) Arch_1000
( YP_003697339.1 )

leucyl-tRNA synthetase

NC_014218
(Arcanobacterium haemolyticum DSM 20595)

1e-142

1555) leuS
( YP_007956246.1 )

leucyl-tRNA ligase

NC_021192
(Mycobacterium tuberculosis Haarlem/NITR202)

1e-142

1556) Deima_1796
( YP_004171109.1 )

leucyl-tRNA synthetase

NC_014958
(Deinococcus maricopensis DSM 21211)

6e-143

1557) leuS
( YP_007231515.1 )

leucyl-tRNA ligase

NC_019905
(Pseudomonas putida PC9)

8e-143

1558) Mmol_0582
( YP_003048019.1 )

leucyl-tRNA synthetase

NC_012968
(Methylotenera mobilis JLW8)

1e-142

1559) leuS
( YP_610252.1 )

leucyl-tRNA synthetase

NC_008027
(Pseudomonas entomophila L48)

2e-142

1560) PPS_4636
( YP_004704047.1 )

leucyl-tRNA synthetase

NC_015733
(Pseudomonas putida S16)

2e-142

1561) Mfla_2155
( YP_546263.1 )

leucyl-tRNA synthetase

NC_007947
(Methylobacillus flagellatus KT)

3e-142

1562) leuS
( YP_001747501.1 )

leucyl-tRNA synthetase

NC_010501
(Pseudomonas putida W619)

3e-142

1563) leuS
( YP_003149513.1 )

leucyl-tRNA synthetase

NC_013169
(Kytococcus sedentarius DSM 20547)

4e-142

1564) leuS
( YP_350685.1 )

leucyl-tRNA synthetase

NC_007492
(Pseudomonas fluorescens Pf0-1)

4e-142

1565) leuS
( YP_007685802.1 )

hypothetical protein

NC_020891
(Clavibacter michiganensis NCPPB 2581)

4e-142

1566) leuS
( YP_001189266.1 )

leucyl-tRNA synthetase

NC_009439
(Pseudomonas mendocina ymp)

5e-142

1567) leuS
( YP_001175908.1 )

leucyl-tRNA synthetase

NC_009436
(Enterobacter sp. 638)

7e-142

1568) Olsu_1022
( YP_003801013.1 )

leucyl-tRNA synthetase

NC_014363
(Olsenella uli DSM 7084)

1e-141

1569) leuS
( YP_004669294.1 )

leucyl-tRNA synthetase

NC_015711
(Myxococcus fulvus HW-1)

9e-142

1570) F750_2393
( YP_007859368.1 )

leucyl-tRNA synthetase

NC_021055
(Streptomyces sp. PAMC26508)

3e-141

1571) BAST_0705
( YP_006864858.1 )

leucine--tRNA ligase

NC_018720
(Bifidobacterium asteroides PRL2011)

3e-141

1572) Ornrh_0971
( YP_006426957.1 )

leucyl-tRNA synthetase

NC_018016
(Ornithobacterium rhinotracheale DSM 15997)

3e-141

1573) leuS
( YP_001710466.1 )

leucyl-tRNA synthetase

NC_010407
(Clavibacter michiganensis ATCC33113)

3e-141

1574) Sfla_4314
( YP_004925239.1 )

leucyl-tRNA synthetase

NC_016114
(Streptomyces flavogriseus ATCC 33331)

6e-141

1575) leuS
( YP_007594427.1 )

leucyl-tRNA ligase

NC_020546
(Bifidobacterium thermophilum RBL67)

2e-140

1576) Psefu_3459
( YP_004475515.1 )

leucyl-tRNA synthetase

NC_015556
(Pseudomonas fulva 12-X)

2e-140

1577) SCD_n00053
( YP_008544934.1 )

leucyl-tRNA synthetase

NC_022357
(Sulfuricella denitrificans skB26)

2e-140

1578) leuS
( YP_956812.1 )

leucyl-tRNA synthetase

NC_008726
(Mycobacterium vanbaalenii PYR-1)

3e-140

1579) CARG_09545
( YP_008479644.1 )

leucyl-tRNA synthetase

NC_022198
(Corynebacterium argentoratense DSM 44202)

3e-140

1580) MAB_4923c
( YP_001705645.1 )

Leucyl-tRNA synthetase

NC_010397
(Mycobacterium abscessus ATCC 19977)

3e-140

1581) leuS
( YP_006525841.1 )

leucyl-tRNA ligase

NC_018177
(Pseudomonas stutzeri DSM 10701)

4e-140

1582) leuS
( NP_626809.1 )

leucyl-tRNA synthetase

NC_003888
(Streptomyces coelicolor A3(2))

5e-140

1583) leuS
( YP_008372467.1 )

leucyl-tRNA ligase

NC_021915
(Corynebacterium maris DSM 45190)

1e-139

1584) leuS
( YP_008058110.1 )

leucyl-tRNA ligase

NC_018868
(Simiduia agarivorans SA1)

9e-140

1585) leuS
( YP_007524228.1 )

Leucyl-tRNA synthetase

NC_020504
(Streptomyces davawensis JCM 4913)

1e-139

1586) leuS
( YP_003117483.1 )

leucyl-tRNA synthetase

NC_013131
(Catenulispora acidiphila DSM 44928)

1e-139

1587) leuS
( YP_003491595.1 )

leucyl-tRNA synthetase

NC_013929
(Streptomyces scabiei 87.22)

2e-139

1588) leuS
( YP_741244.1 )

leucyl-tRNA synthetase

NC_008340
(Alkalilimnicola ehrlichii MLHE-1)

2e-139

1589) leuS
( YP_007707797.1 )

leucyl-tRNA ligase

NC_020912
(Pseudomonas aeruginosa B136-33)

2e-139

1590) leuS
( YP_789131.1 )

leucyl-tRNA synthetase

NC_008463
(Pseudomonas aeruginosa UCBPP-PA14)

2e-139

1591) leuS [H]
( YP_007217648.1 )

Leucyl-tRNA synthetase

NC_019902
(Thioalkalivibrio nitratireducens DSM 14787)

2e-139

1592) MycrhN_1794
( YP_004999620.1 )

leucyl-tRNA synthetase

NC_016604
(Mycobacterium rhodesiae NBB3)

3e-139

1593) leuS
( NP_900175.1 )

leucyl-tRNA synthetase

NC_005085
(Chromobacterium violaceum ATCC 12472)

3e-139

1594) leuS
( YP_005902421.1 )

leucyl-tRNA synthetase

NC_017517
(Neisseria meningitidis M01-240355)

4e-139

1595) leuS
( YP_002438594.1 )

leucyl-tRNA synthetase

NC_011770
(Pseudomonas aeruginosa LESB58)

4e-139

1596) leuS
( YP_002794124.1 )

leucyl-tRNA synthetase

NC_012559
(Laribacter hongkongensis HLHK9)

5e-139

1597) leuS
( YP_006480872.1 )

leucyl-tRNA synthetase

NC_018080
(Pseudomonas aeruginosa DK2)

5e-139

1598) leuS
( YP_005973541.1 )

leucyl-tRNA synthetase

NC_017548
(Pseudomonas aeruginosa M18)

5e-139

1599) leuS
( NP_252676.1 )

leucyl-tRNA synthetase

NC_002516
(Pseudomonas aeruginosa PAO1)

5e-139

1600) leuS
( YP_008134621.1 )

leucyl-tRNA synthetase

NC_021577
(Pseudomonas aeruginosa RP73)

5e-139

1601) BIF_00793
( YP_005576784.1 )

leucyl-tRNA synthetase

NC_017214
(Bifidobacterium animalis BB-12)

6e-139

1602) BALAC2494_00374
( YP_005577930.1 )

Leucine--tRNA ligase

NC_017215
(Bifidobacterium animalis CNCM I-2494)

6e-139

1603) leuS
( YP_006522400.1 )

Leucine--tRNA ligase

NC_018150
(Mycobacterium abscessus GO 06)

6e-139

1604) Echvi_2126
( YP_007224387.1 )

leucyl-tRNA synthetase

NC_019904
(Echinicola vietnamensis DSM 17526)

6e-139

1605) Bl12_0705
( YP_008143536.1 )

leucyl-tRNA synthetase

NC_021593
(animalis lactis Bl12)

6e-139

1606) leuS
( YP_002470140.1 )

leucyl-tRNA synthetase

NC_011835
(Bifidobacterium animalis AD011)

6e-139

1607) W7Y_0757
( YP_006300703.1 )

leucyl-tRNA synthetase

NC_017866
(Bifidobacterium animalis B420)

6e-139

1608) W91_0779
( YP_006302284.1 )

leucyl-tRNA synthetase

NC_017867
(Bifidobacterium animalis Bi-07)

6e-139

1609) BLC1_0721
( YP_005579532.1 )

leucyl-tRNA synthetase

NC_017216
(Bifidobacterium animalis BLC1)

6e-139

1610) leuS
( YP_003360670.1 )

leucyl-tRNA synthetase

NC_013714
(Bifidobacterium dentium Bd1)

6e-139

1611) Thicy_1389
( YP_004537630.1 )

leucyl-tRNA synthetase

NC_015581
(Thioalkalimicrobium cyclicum ALM1)

6e-139

1612) MASS_4924
( YP_008025390.1 )

leucine--tRNA ligase

NC_021282
(Mycobacterium abscessus 50594)

7e-139

1613) leuS
( YP_001598485.1 )

leucyl-tRNA synthetase

NC_010120
(Neisseria meningitidis 053442)

7e-139

1614) leuS
( YP_121740.1 )

leucyl-tRNA synthetase

NC_006361
(Nocardia farcinica IFM 10152)

8e-139

1615) leuS
( YP_006279922.1 )

leucyl-tRNA synthetase

NC_017834
(Bifidobacterium animalis ATCC 25527)

8e-139

1616) DGo_CA2006
( YP_006261391.1 )

putative Leucine--tRNA ligase

NC_017790
(Deinococcus gobiensis I-0)

1e-138

1617) leuS
( YP_004049395.1 )

leucyl-tRNA synthetase

NC_014752
(Neisseria lactamica 020-06)

1e-138

1618) leuS
( YP_003082506.1 )

leucyl-tRNA synthetase

NC_013016
(Neisseria meningitidis alpha14)

1e-138

1619) leuS
( YP_005895133.1 )

leucyl-tRNA synthetase

NC_017514
(Neisseria meningitidis M01-240149)

1e-138

1620) leuS
( YP_005898496.1 )

leucyl-tRNA synthetase

NC_017515
(Neisseria meningitidis M04-240196)

1e-138

1621) leuS
( YP_001346507.1 )

leucyl-tRNA synthetase

NC_009656
(Pseudomonas aeruginosa PA7)

1e-138

1622) leuS
( YP_002968186.1 )

leucyl-tRNA synthetase

NC_012814
(Bifidobacterium animalis Bl-04)

2e-138

1623) leuS
( YP_002969753.1 )

leucyl-tRNA synthetase

NC_012815
(Bifidobacterium animalis DSM 10140)

2e-138

1624) leuS
( YP_005581095.1 )

leucyl-tRNA synthetase

NC_017217
(Bifidobacterium animalis V9)

2e-138

1625) LeuS
( YP_004711777.1 )

leucyl-tRNA synthetase

NC_015738
(Eggerthella sp. YY7918)

2e-138

1626) leuS
( YP_005893235.1 )

leucyl-tRNA synthetase

NC_017513
(Neisseria meningitidis G2136)

2e-138

1627) leuS
( YP_006456214.1 )

leucyl-tRNA ligase

NC_018028
(Pseudomonas stutzeri CCUG 29243)

2e-138

1628) leuS
( YP_004911141.1 )

leucyl-tRNA synthetase

NC_016111
(Streptomyces cattleya NRRL 8057)

3e-138

1629) SCATT_16200
( YP_006053513.1 )

leucyl-tRNA synthetase

NC_017586
(Streptomyces cattleya NRRL 8057)

3e-138

1630) Strvi_7871
( YP_004817480.1 )

leucyl-tRNA synthetase

NC_015957
(Streptomyces violaceusniger Tu 4113)

3e-138

1631) Tpau_4214
( YP_003649121.1 )

leucyl-tRNA synthetase

NC_014158
(Tsukamurella paurometabola DSM 20162)

3e-138

1632) NMBB_2163
( YP_005883443.1 )

putative leucyl-tRNA synthetase

NC_017505
(Neisseria meningitidis alpha710)

3e-138

1633) leuS
( YP_974439.1 )

leucyl-tRNA synthetase

NC_008767
(Neisseria meningitidis FAM18)

3e-138

1634) leuS
( YP_005900460.1 )

leucyl-tRNA synthetase

NC_017516
(Neisseria meningitidis H44/76)

4e-138

1635) leuS
( NP_274892.1 )

leucyl-tRNA synthetase

NC_003112
(Neisseria meningitidis MC58)

4e-138

1636) leuS
( NP_826665.1 )

leucyl-tRNA synthetase

NC_003155
(Streptomyces avermitilis MA-4680)

5e-138

1637) Tmar_2197
( YP_004103004.1 )

leucyl-tRNA synthetase

NC_014831
(Thermaerobacter marianensis DSM 12885)

6e-138

1638) leuS
( YP_005879281.1 )

leucyl-tRNA synthetase (leucine--tRNA ligase; LeuRS)

NC_017501
(Neisseria meningitidis 8013)

6e-138

1639) Belba_0205
( YP_006405628.1 )

leucyl-tRNA synthetase

NC_018010
(Belliella baltica DSM 15883)

1e-137

1640) leuS
( YP_001708122.1 )

leucyl-tRNA synthetase

NC_010400
(Acinetobacter baumannii SDF)

1e-137

1641) leuS
( YP_002000634.1 )

leucyl-tRNA synthetase

NC_011035
(Neisseria gonorrhoeae NCCP11945)

1e-137

1642) leuS
( YP_005890986.1 )

leucyl-tRNA synthetase

NC_017511
(Neisseria gonorrhoeae TCDC-NG08107)

1e-137

1643) XNR_4367
( YP_007747696.1 )

Leucyl-tRNA synthetase

NC_020990
(Streptomyces albus J1074)

2e-137

1644) leuS
( YP_001538244.1 )

leucyl-tRNA synthetase

NC_009953
(Salinispora arenicola CNS-205)

2e-137

1645) leuS
( YP_005983393.1 )

leucyl-tRNA synthetase

NC_017549
(Pseudomonas aeruginosa NCGM2.S1)

2e-137

1646) leuS
( YP_207190.1 )

leucyl-tRNA synthetase

NC_002946
(Neisseria gonorrhoeae FA 1090)

8e-138

1647) leuS
( YP_002322486.1 )

leucyl-tRNA synthetase

NC_011593
(Bifidobacterium longum JCM 1222)

2e-137

1648) BLIJ_1032
( YP_005584790.1 )

leucyl-tRNA synthetase

NC_017219
(Bifidobacterium longum JCM 1222)

2e-137

1649) leuS
( YP_904302.1 )

leucyl-tRNA synthetase

NC_008611
(Mycobacterium ulcerans Agy99)

3e-137

1650) leuS
( YP_003661418.1 )

leucyl-tRNA synthetase

NC_014169
(Bifidobacterium longum JDM301)

3e-137

1651) leuS
( YP_909727.1 )

leucyl-tRNA synthetase

NC_008618
(Bifidobacterium adolescentis ATCC 15703)

4e-137

1652) leuS
( YP_003999965.1 )

leus

NC_014656
(Bifidobacterium longum BBMN68)

4e-137

1653) leuS
( YP_001954272.1 )

leucyl-tRNA synthetase

NC_010816
(Bifidobacterium longum DJO10A)

4e-137

1654) BLLJ_1149
( YP_004220908.1 )

leucyl-tRNA synthase

NC_015067
(Bifidobacterium longum JCM 1217)

4e-137

1655) BIL_08230
( YP_007767386.1 )

leucyl-tRNA synthetase

NC_021008
(Bifidobacterium longum F8)

5e-137

1656) leuS
( YP_003374157.1 )

leucyl-tRNA synthetase

NC_013721
(Gardnerella vaginalis 409-05)

6e-137

1657) leuS
( YP_001848383.1 )

leucyl-tRNA synthetase

NC_010612
(Mycobacterium marinum M)

1e-136

1658) leuS
( YP_006394485.1 )

leucyl-tRNA synthetase

NC_017999
(Bifidobacterium bifidum BGN4)

1e-136

1659) leuS
( YP_003971188.1 )

leucyl-tRNA synthetase LeuS

NC_014638
(Bifidobacterium bifidum PRL2010)

7e-137

1660) leuS
( YP_005582616.1 )

leucyl-tRNA synthetase

NC_017218
(Bifidobacterium breve ACS-071-V-Sch8b)

7e-137

1661) leuS
( YP_007554933.1 )

Leucyl-tRNA synthetase

NC_020517
(Bifidobacterium breve UCC2003)

7e-137

1662) leuS
( YP_003938808.1 )

leucyl-tRNA synthetase

NC_014616
(Bifidobacterium bifidum S17)

8e-137

1663) leuS
( YP_005587124.1 )

leucyl-tRNA synthetase

NC_017221
(Bifidobacterium longum KACC 91563)

8e-137

1664) leuS
( NP_696609.1 )

leucyl-tRNA synthetase

NC_004307
(Bifidobacterium longum NCC2705)

8e-137

1665) SVEN_2353
( YP_006877898.1 )

Leucyl-tRNA synthetase

NC_018750
(Streptomyces venezuelae ATCC 10712)

9e-137

1666) Intca_1421
( YP_004098664.1 )

leucyl-tRNA synthetase

NC_014830
(Intrasporangium calvum DSM 43043)

9e-137

1667) NH8B_3906
( YP_004849067.1 )

leucyl-tRNA synthetase

NC_016002
(Pseudogulbenkiania sp. NH8B)

9e-137

1668) leuS
( YP_003718970.1 )

leucine--tRNA ligase

NC_014246
(Mobiluncus curtisii ATCC 43063)

2e-136

1669) leuS
( YP_004965395.1 )

leucyl-tRNA synthetase

NC_016582
(Streptomyces bingchenggensis BCW-1)

3e-136

1670) BLIF_1140
( YP_004209060.1 )

leucyl-tRNA synthase

NC_015052
(Bifidobacterium longum 157F)

3e-136

1671) leuS
( YP_001209169.1 )

leucyl-tRNA synthetase

NC_009446
(Dichelobacter nodosus VCS1703A)

3e-136

1672) leuS
( YP_005838169.1 )

leucyl-tRNA synthetase

NC_017456
(Gardnerella vaginalis HMP9231)

4e-136

1673) leuS
( YP_003985838.1 )

leucyl-tRNA synthetase

NC_014644
(Gardnerella vaginalis ATCC 14019)

1e-135

1674) leuS
( YP_004407047.1 )

leucyl-tRNA synthetase

NC_015434
(Verrucosispora maris AB-18-032)

2e-135

1675) leuS
( YP_007366702.1 )

leucyl-tRNA synthetase LeuS

NC_020133
(Mycobacterium liflandii 128FXT)

2e-135

1676) MDS_4091
( YP_004381874.1 )

leucyl-tRNA synthetase

NC_015410
(Pseudomonas mendocina NK-01)

2e-135

1677) leuS
( YP_001826485.1 )

leucyl-tRNA synthetase

NC_010572
(Streptomyces griseus NBRC 13350)

3e-135

1678) Alfi_1697
( YP_006410713.1 )

leucyl-tRNA synthetase

NC_018011
(Alistipes finegoldii DSM 17242)

3e-135

1679) Sked_13250
( YP_003314099.1 )

leucyl-tRNA synthetase

NC_013521
(Sanguibacter keddieii DSM 10542)

4e-135

1680) AciPR4_3119
( YP_004183871.1 )

leucyl-tRNA synthetase

NC_014963
(Terriglobus saanensis SP1PR4)

4e-135

1681) Gobs_3367
( YP_003410340.1 )

leucyl-tRNA synthetase

NC_013757
(Geodermatophilus obscurus DSM 43160)

7e-135

1682) Isova_2002
( YP_004542632.1 )

leucyl-tRNA synthetase

NC_015588
(Isoptericola variabilis 225)

8e-135

1683) SFUL_2132
( YP_007930976.1 )

Leucyl-tRNA synthetase

NC_021177
(Streptomyces fulvissimus DSM 40593)

1e-134

1684) leuS
( YP_002502787.1 )

leucyl-tRNA synthetase

NC_011896
(Mycobacterium leprae Br4923)

2e-134

1685) leuS
( NP_301156.1 )

leucyl-tRNA synthetase

NC_002677
(Mycobacterium leprae TN)

2e-134

1686) FraEuI1c_0670
( YP_004014618.1 )

leucyl-tRNA synthetase

NC_014666
(Frankia sp. EuI1c)

4e-134

1687) SHJG_4065
( YP_006245210.1 )

leucyl-tRNA synthetase

NC_017765
(Streptomyces hygroscopicus 5008)

4e-134

1688) SHJGH_3830
( YP_007692829.1 )

leucyl-tRNA synthetase

NC_020895
(Streptomyces hygroscopicus TL01)

4e-134

1689) leuS
( YP_003575776.1 )

leucine--tRNA ligase

NC_014033
(Prevotella ruminicola 23)

5e-134

1690) leuS
( YP_001958396.1 )

leucyl-tRNA synthetase

NC_010830
(Candidatus Amoebophilus asiaticus 5a2)

1e-133

1691) Jden_1568
( YP_003161519.1 )

leucyl-tRNA synthetase

NC_013174
(Jonesia denitrificans DSM 20603)

2e-133

1692) leuS
( YP_003093791.1 )

leucyl-tRNA synthetase

NC_013061
(Pedobacter heparinus DSM 2366)

4e-133

1693) Oweho_2745
( YP_004990352.1 )

leucyl-tRNA synthetase

NC_016599
(Owenweeksia hongkongensis DSM 17368)

1e-132

1694) Sph21_0546
( YP_004315798.1 )

leucyl-tRNA synthetase

NC_015277
(Sphingobacterium sp. 21)

8e-133

1695) Srot_0244
( YP_003657562.1 )

leucyl-tRNA synthetase

NC_014168
(Segniliparus rotundus DSM 44985)

2e-132

1696) Lbys_0592
( YP_003996708.1 )

leucyl-tRNA synthetase

NC_014655
(Leadbetterella byssophila DSM 17132)

3e-132

1697) Tgr7_2279
( YP_002514346.1 )

leucyl-tRNA synthetase

NC_011901
(Thioalkalivibrio sulfidophilus HL-EbGR7)

3e-132

1698) leuS
( YP_007891926.1 )

leucyl-tRNA synthetase

NC_021149
(Azotobacter vinelandii CA)

5e-132

1699) leuS
( YP_007896974.1 )

leucyl-tRNA synthetase

NC_021150
(Azotobacter vinelandii CA6)

5e-132

1700) leuS
( YP_002798114.1 )

leucyl-tRNA synthetase

NC_012560
(Azotobacter vinelandii DJ)

5e-132

1701) leuS
( YP_006765647.1 )

leucyl-tRNA synthetase

NC_018649
(Leptospirillum ferriphilum ML-04)

1e-131

1702) leuS
( YP_001192919.1 )

leucyl-tRNA synthetase

NC_009441
(Flavobacterium johnsoniae UW101)

3e-131

1703) leuS
( YP_004525576.1 )

leucyl-tRNA synthetase

NC_015576
(Mycobacterium sp. JDM601)

4e-131

1704) leuS
( YP_003204644.1 )

leucyl-tRNA synthetase

NC_013235
(Nakamurella multipartita DSM 44233)

5e-131

1705) leuS
( YP_004904359.1 )

putative leucyl-tRNA synthetase

NC_016109
(Kitasatospora setae KM-6054)

1e-130

1706) FB2170_07704
( YP_003862432.1 )

leucyl-tRNA synthetase

NC_014472
(Maribacter sp. HTCC2170)

1e-130

1707) leuS
( YP_003094942.1 )

leucyl-tRNA synthetase

NC_013062
(Flavobacteriaceae bacterium 3519-10)

7e-131

1708) leuS
( YP_482980.1 )

leucyl-tRNA synthetase

NC_007777
(Frankia sp. CcI3)

7e-130

1709) Cycma_0967
( YP_004772970.1 )

leucyl-tRNA synthetase

NC_015914
(Cyclobacterium marinum DSM 745)

2e-129

1710) Bacsa_2284
( YP_004259306.1 )

leucyl-tRNA synthetase

NC_015164
(Bacteroides salanitronis DSM 18170)

4e-129

1711) leuS
( YP_003120953.1 )

leucyl-tRNA synthetase

NC_013132
(Chitinophaga pinensis DSM 2588)

4e-129

1712) leuS
( YP_005329025.1 )

leucyl-tRNA synthetase

NC_016943
(Blastococcus saxobsidens DD2)

6e-129

1713) leuS
( YP_863043.1 )

leucyl-tRNA synthetase

NC_008571
(Gramella forsetii KT0803)

6e-129

1714) Weevi_1176
( YP_004238463.1 )

leucyl-tRNA synthetase

NC_015144
(Weeksella virosa DSM 16922)

7e-129

1715) leuS
( YP_008386336.1 )

leucyl-tRNA ligase

NC_021985
(Streptomyces collinus Tu 365)

1e-128

1716) leuS
( YP_006367447.1 )

leucyl-tRNA synthetase

NC_017955
(Modestobacter marinus BC501)

1e-128

1717) leuS
( YP_003154688.1 )

leucyl-tRNA synthetase

NC_013172
(Brachybacterium faecium DSM 4810)

2e-128

1718) Emtol_4026
( YP_006875178.1 )

leucyl-tRNA synthetase

NC_018748
(Emticicia oligotrophica DSM 17448)

2e-128

1719) leuS
( YP_005036098.1 )

leucyl-tRNA synthetase

NC_016620
(Bacteriovorax marinus SJ)

3e-128

1720) leuS
( YP_001298462.1 )

leucyl-tRNA synthetase

NC_009614
(Bacteroides vulgatus ATCC 8482)

3e-128

1721) CA2559_04530
( YP_003715670.1 )

leucyl-tRNA synthetase

NC_014230
(Croceibacter atlanticus HTCC2559)

3e-128

1722) leuS
( YP_677899.1 )

leucyl-tRNA synthetase

NC_008255
(Cytophaga hutchinsonii ATCC 33406)

6e-128

1723) leuS
( YP_101857.1 )

leucyl-tRNA synthetase

NC_006347
(Bacteroides fragilis YCH46)

7e-128

1724) leuS
( YP_003194670.1 )

leucyl-tRNA synthetase

NC_013222
(Robiginitalea biformata HTCC2501)

1e-127

1725) Xcel_2223
( YP_003326799.1 )

leucyl-tRNA synthetase

NC_013530
(Xylanimonas cellulosilytica DSM 15894)

2e-127

1726) Poras_0515
( YP_004441637.1 )

leucyl-tRNA synthetase

NC_015501
(Porphyromonas asaccharolytica DSM 20707)

2e-127

1727) leuS
( YP_213927.1 )

leucyl-tRNA synthetase

NC_003228
(Bacteroides fragilis NCTC 9343)

5e-127

1728) Slin_1712
( YP_003386557.1 )

leucyl-tRNA synthetase

NC_013730
(Spirosoma linguale DSM 74)

1e-126

1729) AL1_17720
( YP_007816912.1 )

leucyl-tRNA synthetase

NC_021030
(Alistipes shahii WAL 8301)

6e-127

1730) leuS
( YP_005113458.1 )

putative Leucyl-tRNA synthetase

NC_016776
(Bacteroides fragilis 638R)

6e-127

1731) leuS
( YP_006512239.1 )

leucyl-tRNA synthetase

NC_018142
(Propionibacterium propionicum F0230a)

8e-127

1732) Celgi_1211
( YP_004600298.1 )

leucyl-tRNA synthetase

NC_015671
(Cellvibrio gilvus ATCC 13127)

2e-126

1733) leuS
( YP_001505193.1 )

leucyl-tRNA synthetase

NC_009921
(Frankia sp. EAN1.pec)

3e-126

1734) leuS
( NP_213240.1 )

leucyl-tRNA synthetase

NC_000918
(Aquifex aeolicus VF5)

5e-126

1735) Celf_2373
( YP_004453887.1 )

leucyl-tRNA synthetase

NC_015514
(Cellulomonas fimi ATCC 484)

6e-126

1736) BXY_22580
( YP_007792911.1 )

leucyl-tRNA synthetase

NC_021017
(Bacteroides xylanisolvens XB1A)

2e-125

1737) leuS
( YP_006705686.1 )

leucine--tRNA ligase

NC_018605
(Cardinium endosymbiont cEper1)

5e-125

1738) Bache_0699
( YP_004160308.1 )

leucyl-tRNA synthetase

NC_014933
(Bacteroides helcogenes P 36-108)

3e-124

1739) leuS
( YP_001304338.1 )

leucyl-tRNA synthetase

NC_009615
(Parabacteroides distasonis ATCC 8503)

1e-123

1740) SACTE_1984
( YP_004802429.1 )

leucyl-tRNA synthetase

NC_015953
(Streptomyces sp. SirexAA-E)

1e-123

1741) Odosp_2649
( YP_004253808.1 )

leucyl-tRNA synthetase

NC_015160
(Odoribacter splanchnicus DSM 220712)

2e-123

1742) leuS
( NP_812038.1 )

leucyl-tRNA synthetase

NC_004663
(Bacteroides thetaiotaomicron VPI-5482)

3e-123

1743) leuS
( YP_001297219.1 )

Leucine--tRNA ligase

NC_009613
(Flavobacterium psychrophilum JIP02/86)

3e-123

1744) C427_3472
( YP_007544929.1 )

leucyl-tRNA synthetase

NC_020514
(Glaciecola psychrophila 170)

2e-122

1745) leuS
( YP_005445162.1 )

leucyl-tRNA synthetase

NC_017080
(Phycisphaera mikurensis NBRC 102666)

3e-121

1746) Niako_6939
( YP_005012564.1 )

leucyl-tRNA synthetase

NC_016609
(Niastella koreensis GR20-10)

1e-120

1747) leuS
( YP_004510627.1 )

leucyl-tRNA synthetase

NC_015571
(Porphyromonas gingivalis TDC60)

1e-120

1748) Ftrac_1194
( YP_004053297.1 )

leucyl-tRNA synthetase

NC_014759
(Marivirga tractuosa DSM 4126)

8e-120

1749) Pedsa_0250
( YP_004272658.1 )

leucyl-tRNA synthetase

NC_015177
(Pedobacter saltans DSM 12145)

1e-119

1750) leuS
( NP_905058.1 )

leucyl-tRNA synthetase

NC_002950
(Porphyromonas gingivalis W83)

3e-119

1751) Riean_0951
( YP_004045618.1 )

leucyl-tRNA synthetase

NC_014738
(Riemerella anatipestifer ATCC 11845)

4e-119

1752) RA0C_1213
( YP_005394657.1 )

leucyl-tRNA synthetase

NC_017045
(Riemerella anatipestifer ATCC 11845)

4e-119

1753) G148_0667
( YP_007355665.1 )

Leucyl-tRNA synthetase

NC_020125
(Riemerella anatipestifer RA-CH-2)

4e-119

1754) RIA_1286
( YP_006017734.1 )

leucyl-tRNA synthetase

NC_017569
(Riemerella anatipestifer RA-GD)

4e-119

1755) leuS
( YP_001928935.1 )

leucyl-tRNA synthetase

NC_010729
(Porphyromonas gingivalis ATCC 33277)

5e-119

1756) B739_0929
( YP_006723428.1 )

leucyl-tRNA synthetase

NC_018609
(Riemerella anatipestifer RA-CH-1)

8e-119

1757) Solca_2951
( YP_006257146.1 )

leucyl-tRNA synthetase

NC_017770
(Solitalea canadensis DSM 3403)

3e-118

1758) leuS
( YP_002309307.1 )

leucyl-tRNA synthetase

NC_011565
(Candidatus Azobacteroides pseudotrichonymphae CFP2)

3e-118

1759) Runsl_3682
( YP_004657172.1 )

leucyl-tRNA synthetase

NC_015703
(Runella slithyformis DSM 19594)

2e-115

1760) leuS
( YP_003087016.1 )

leucyl-tRNA synthetase

NC_013037
(Dyadobacter fermentans DSM 18053)

3e-114

1761) leuS
( YP_005787651.1 )

leucyl-tRNA synthetase

NC_017376
(Helicobacter pylori Santal49)

3e-108

• Sequence Alignments

1) leuS in NC_004070


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1295 bits (4913),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 827/833 (99%), Positives = 832/833 (99%), Gaps = 0/833 (0%)

Query  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60
            MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120
            ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180
            WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  181  GYPVVRKPMRQWMLKITVYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240
            GYPVVRKPMRQWMLKIT YAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  241  KNFTVFTTRPDTLFGATYAVLAPEHALVDAITTADQAEAVADYKRQASLKSDLARTDLAK  300
            K+FTVFTTRPDTLFGATYAVLAPEHALVDAITT+DQAEAVADYKRQASLKSDLARTDLAK
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  301  EKTGVWTGSYAINPVNGKEIPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360
            EKTGVWTGSYAINPVNGKE+PVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  361  VLEGGNVEEAAFTEDGLHINSGFLDGLDKASAIAKMVEWLEAEGVGNEKVTYRLRDWLFS  420
            VLEGGNVEEAAFTEDGLHINS+FLDGLDKASAIAKMVEWLEAEGVGNE+VTYRLRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480
            RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540
            GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600
            YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660
            GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720
            LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK
Sbjct  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIk  780
            LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK
Sbjct  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK  780

Query  781  gkvkaklvvakDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833
            GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK
Sbjct  781  GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

2) leuS in NC_004606


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1295 bits (4913),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 827/833 (99%), Positives = 832/833 (99%), Gaps = 0/833 (0%)

Query  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60
            MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120
            ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180
            WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  181  GYPVVRKPMRQWMLKITVYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240
            GYPVVRKPMRQWMLKIT YAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  241  KNFTVFTTRPDTLFGATYAVLAPEHALVDAITTADQAEAVADYKRQASLKSDLARTDLAK  300
            K+FTVFTTRPDTLFGATYAVLAPEHALVDAITT+DQAEAVADYKRQASLKSDLARTDLAK
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  301  EKTGVWTGSYAINPVNGKEIPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360
            EKTGVWTGSYAINPVNGKE+PVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  361  VLEGGNVEEAAFTEDGLHINSGFLDGLDKASAIAKMVEWLEAEGVGNEKVTYRLRDWLFS  420
            VLEGGNVEEAAFTEDGLHINS+FLDGLDKASAIAKMVEWLEAEGVGNE+VTYRLRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480
            RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540
            GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600
            YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660
            GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720
            LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK
Sbjct  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIk  780
            LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK
Sbjct  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK  780

Query  781  gkvkaklvvakDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833
            GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK
Sbjct  781  GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

3) leuS in NC_018936


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1265 bits (4800),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 833/833 (100%), Positives = 833/833 (100%), Gaps = 0/833 (0%)

Query  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60
            MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120
            ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180
            WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANvtfkvkdtd  240
            GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  241  kdftvfttRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300
            KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360
            EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420
            VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480
            RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540
            GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600
            YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660
            GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720
            LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK
Sbjct  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIk  780
            LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK
Sbjct  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK  780

Query  781  gkvkaklvvakDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833
            GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK
Sbjct  781  GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

4) leuS in NC_020540


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1265 bits (4800),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 833/833 (100%), Positives = 833/833 (100%), Gaps = 0/833 (0%)

Query  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60
            MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120
            ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180
            WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANvtfkvkdtd  240
            GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  241  kdftvfttRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300
            KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360
            EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420
            VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480
            RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540
            GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600
            YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660
            GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720
            LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK
Sbjct  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIk  780
            LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK
Sbjct  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK  780

Query  781  gkvkaklvvakDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833
            GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK
Sbjct  781  GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

5) leuS in NC_008023


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1265 bits (4800),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 833/833 (100%), Positives = 833/833 (100%), Gaps = 0/833 (0%)

Query  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60
            MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120
            ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180
            WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANvtfkvkdtd  240
            GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  241  kdftvfttRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300
            KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360
            EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420
            VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480
            RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540
            GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600
            YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660
            GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720
            LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK
Sbjct  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIk  780
            LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK
Sbjct  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK  780

Query  781  gkvkaklvvakDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833
            GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK
Sbjct  781  GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

6) leuS in NC_007297


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1265 bits (4800),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 833/833 (100%), Positives = 833/833 (100%), Gaps = 0/833 (0%)

Query  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60
            MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120
            ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180
            WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANvtfkvkdtd  240
            GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  241  kdftvfttRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300
            KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360
            EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420
            VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480
            RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540
            GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600
            YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660
            GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720
            LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK
Sbjct  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIk  780
            LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK
Sbjct  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK  780

Query  781  gkvkaklvvakDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833
            GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK
Sbjct  781  GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

7) leuS in NC_008021


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1265 bits (4800),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 833/833 (100%), Positives = 833/833 (100%), Gaps = 0/833 (0%)

Query  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60
            MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120
            ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180
            WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANvtfkvkdtd  240
            GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  241  kdftvfttRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300
            KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360
            EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420
            VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480
            RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540
            GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600
            YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660
            GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720
            LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK
Sbjct  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIk  780
            LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK
Sbjct  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK  780

Query  781  gkvkaklvvakDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833
            GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK
Sbjct  781  GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

8) leuS in NC_008022


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1264 bits (4795),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 830/833 (99%), Positives = 833/833 (100%), Gaps = 0/833 (0%)

Query  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60
            MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120
            ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180
            WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANvtfkvkdtd  240
            GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  241  kdftvfttRPDTLFGATYAVLAPEHALVDAITTADQAEAVADYKRQASLKSDLARTDLAK  300
            KDFTVFTTRPDTLFGATYAVLAPEHALVDAITT+DQAEAVADYKRQASLKSDLARTDLAK
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360
            EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  361  VLEGGNVEEAAFTEDGLHINSGFLDGLDKASAIAKMVEWLEAEGVGNEKVTYRLRDWLFS  420
            VLEGGNVEEAAFTEDGLHINS+FLDGLDKASAIAKMVEWLEAEGVGNE+VTYRLRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480
            RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540
            GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600
            YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660
            GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720
            LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK
Sbjct  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIk  780
            LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK
Sbjct  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK  780

Query  781  gkvkaklvvakDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833
            GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK
Sbjct  781  GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

9) leuS in NC_017596


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1263 bits (4793),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 830/833 (99%), Positives = 833/833 (100%), Gaps = 0/833 (0%)

Query  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60
            MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120
            ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180
            WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANvtfkvkdtd  240
            GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  241  kdftvfttRPDTLFGATYAVLAPEHALVDAITTADQAEAVADYKRQASLKSDLARTDLAK  300
            KDFTVFTTRPDTLFGATYAVLAPEHALVDAITT+DQAEAVADYKRQASLKSDLARTDLAK
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  301  EKTGVWTGSYAINPVNGNEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360
            EKTGVWTGSYAINPVNG+EMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNEKVTYRLRDWLFS  420
            VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNE+VTYRLRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480
            RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540
            GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600
            YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660
            GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720
            LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK
Sbjct  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIk  780
            LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK
Sbjct  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK  780

Query  781  gkvkaklvvakDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833
            GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK
Sbjct  781  GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

10) leuS in NC_009332


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1262 bits (4786),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 828/833 (99%), Positives = 833/833 (100%), Gaps = 0/833 (0%)

Query  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60
            MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120
            ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180
            WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANvtfkvkdtd  240
            GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  241  kdftvfttRPDTLFGATYAVLAPEHALVDAITTADQAEAVADYKRQASLKSDLARTDLAK  300
            KDFTVFTTRPDTLFGATYAVLAPEHALVDAITT+DQAEAVADYKRQASLKSDLARTDLAK
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  301  EKTGVWTGSYAINPVNGNEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360
            EKTGVWTGSYAINPVNG+EMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  361  VLEGGNVEEAAFTEDGLHINSGFLDGLDKASAIAKMVEWLEAEGVGNEKVTYRLRDWLFS  420
            VLEGGNVEEAAFTEDGLHINS+FLDGLDKASAIAKMVEWLEAEGVGNE+VTYRLRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480
            RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540
            GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHLET  600
            YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFH+ET
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660
            GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720
            LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK
Sbjct  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIk  780
            LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK
Sbjct  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK  780

Query  781  gkvkaklvvakDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833
            GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK
Sbjct  781  GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

11) leuS in NC_008024


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1262 bits (4787),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 829/833 (99%), Positives = 833/833 (100%), Gaps = 0/833 (0%)

Query  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60
            MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120
            ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180
            WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIDKSTGANvtfkvkdtd  240
            GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWI+KSTGANVTFKVKDTD
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  241  kdftvfttRPDTLFGATYAVLAPEHALVDAITTADQAEAVADYKRQASLKSDLARTDLAK  300
            KDFTVFTTRPDTLFGATYAVLAPEHALVDAITT+DQAEAVADYKRQASLKSDLARTDLAK
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  301  EKTGVWTGSYAINPVNGNEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360
            EKTGVWTGSYAINPVNG+EMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNEKVTYRLRDWLFS  420
            VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNE+VTYRLRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480
            RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540
            GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600
            YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660
            GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720
            LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK
Sbjct  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIk  780
            LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK
Sbjct  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK  780

Query  781  gkvkaklvvakDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833
            GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK
Sbjct  781  GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

12) leuS in NC_007296


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1262 bits (4787),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 827/833 (99%), Positives = 831/833 (99%), Gaps = 0/833 (0%)

Query  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60
            MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120
            ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180
            WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANvtfkvkdtd  240
            GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  241  kdftvfttRPDTLFGATYAVLAPEHALVDAITTADQAEAVADYKRQASLKSDLARTDLAK  300
            KDFTVFTTRPDTLFGATYAVLAPEHALVDAITT+DQAEAVADYKRQASLKSDLARTDLAK
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  301  EKTGVWTGSYAINPVNGNEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFKLDIIP  360
            EKTGVWTGSYAINPVNG+EMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQF+LDIIP
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNEKVTYRLRDWLFS  420
            VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNE+VTYRLRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480
            RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540
            GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600
            YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660
            GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720
            LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK
Sbjct  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  721  LFSDYAKGFVQLIAPFAPHLGEELWQVLTASGESISYVPWPSYDKSKLVENDVEIVVQIk  780
            LFSDYAKGFVQLIAPFAPHLGEELWQ LTASGESISYVPWPSYD SKLVENDVEIVVQIK
Sbjct  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK  780

Query  781  gkvkaklvvakDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833
            GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK
Sbjct  781  GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

13) leuS in NC_002737


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1260 bits (4782),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 825/833 (99%), Positives = 832/833 (99%), Gaps = 0/833 (0%)

Query  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60
            MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   ILSRFKRAQGHNILHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120
            ILSRFKRAQGHN+LHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180
            WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANvtfkvkdtd  240
            GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  241  kdftvfttRPDTLFGATYAVLAPEHALVDAITTADQAEAVAKYKRQASLKSDLARTDLAK  300
            KDFTVFTTRPDTLFGATYAVLAPEHALVDAITT+DQAEAVA YKRQASLKSDLARTDLAK
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  301  EKTGVWTGAYAINPVNGNEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFKLDIIP  360
            EKTGVWTG+YAINPVNG+EMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQF+LDIIP
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  361  VLEGGNVEEAAFTEDGLHINSGFLDGLDKASAIAKMVEWLEAEGVGNEKVTYRLRDWLFS  420
            VLEGGNVEEAAFTEDGLHINS+FLDGLDKASAIAKMVEWLEAEGVGNE+VTYRLRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480
            RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540
            GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600
            YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660
            GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720
            LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK
Sbjct  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIk  780
            LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK
Sbjct  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK  780

Query  781  gkvkaklvvakDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833
            GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK
Sbjct  781  GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

14) leuS in NC_006086


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1260 bits (4782),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 827/833 (99%), Positives = 832/833 (99%), Gaps = 0/833 (0%)

Query  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60
            MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120
            ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180
            WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANvtfkvkdtd  240
            GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  241  kdftvfttRPDTLFGATYAVLAPEHALVDAITTADQAEAVADYKRQASLKSDLARTDLAK  300
            KDFTVFTTRPDTLFGATYAVLAPEHALVDAITT+DQAEAVADYKRQASLKSDLARTDLAK
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  301  EKTGVWTGSYAINPVNGNEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360
            EKTGVWTGSYAINPVNG+EMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  361  VLEGGNVEEAAFTEDGLHINSGFLDGLDKASAIAKMVEWLEAEGVGNEKVTYRLRDWLFS  420
            VLEGGNVEEAAFTEDGLHINS+FLDGLDKASAIAKMVEWLEAEGVGNE+VTYRLRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480
            RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540
            GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600
            YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660
            GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720
            LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK
Sbjct  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDKSKLVENDVEIVVQIk  780
            LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYD SKLVENDVEIVVQIK
Sbjct  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK  780

Query  781  gkvkaklvvakDLSREELQEVALANEKVQAEITGKDIIKVIAVPNKLVNIVIK  833
            GKVKAKLVVAKDLSREELQEVALANEKVQAEI+GKDIIKVIAVPNKLVNIVIK
Sbjct  781  GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

15) leuS in NC_011375


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1260 bits (4781),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 828/833 (99%), Positives = 831/833 (99%), Gaps = 0/833 (0%)

Query  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60
            MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120
            ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WDREVNTTDPNYYKWTQWIFTELYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180
            WDREVNTTDPNYYKWTQWIFT LYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANvtfkvkdtd  240
            GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  241  kdftvfttRPDTLFGATYAVLAPEHALVDAITTADQAEAVADYKRQASLKSDLARTDLAK  300
            KDFTVFTTRPDTLFGATYAVLAPEHALVDAITT+DQAEAVADYKRQASLKSDLARTDLAK
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  301  EKTGVWTGSYAINPVNGNEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360
            EKTGVWTGSYAINPVNG+EMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNEKVTYRLRDWLFS  420
            VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNE+VTYRLRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480
            RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540
            GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600
            YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660
            GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720
            LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK
Sbjct  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDKSKLVENDVEIVVQIk  780
            LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYD SKLVENDVEIVVQIK
Sbjct  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK  780

Query  781  gkvkaklvvakDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833
            GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK
Sbjct  781  GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

16) leuS in NC_013853


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1260 bits (4779),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 757/833 (91%), Positives = 812/833 (98%), Gaps = 0/833 (0%)

Query  1    MSFYNHKEIEPKWQSYWAEHHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60
            M+FY+H  IEPKWQ++WA++HTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   ILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120
            ILSR+KRAQG NVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180
            WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  181  GYPVVRKPMRQWMLKITAYAERLLNDLDELDWPESIKDMQRNWIGKSTGSNVTFKVKGTD  240
            GYPVVRKPMRQWMLKITAYAERLL+DL+E+DWPESIKDMQRNWIGKSTG+NVTFKVK+TD
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  241  KEFTVFTTRPDTLFGATFTVLAPEHDLVDAITSPEQAEAVADYKHQASLKSDLARTDLAK  300
            K+FTVFTTRPDTLFGAT++VLAPEH LVDAIT+++QAEAVADYK+QASLKSDLARTDLAK
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  301  EKTGVWTGAYAINPVNGKEIPIWIADYVLASYGTGAVMAVPAHDQRDWEFAKQFDLPIVE  360
            EKTGVWTG+YAINPVNGKE+P+WIADYVLASYGTGA+MAVPAHD+RDWEFAKQF+L I+ 
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  361  VLEGGNVAEAAYTEDGLHVNSDFLDGLNKEDAIAKIVSWLEEEGCGQEKVTYRLRDWLFS  420
            VLEGGNV EAA+TEDGLH+NSDFLDGL+K  AIAK+V WLE EG G+E+VTYRLRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANLTDWLEVTRED  480
            RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLAN+TDWLEVTRED
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEDLLKQWLPVDIYVGGAEHAVLHLL  540
            GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADE+LLKQWLPVDIYVGGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  541  YARFWHKFLYDLGVVPTKEPFQKLFNQGMILGTSYRDHRGALVATDKVEKRDGSFFHVET  600
            YARFWHK LYDLGVVPTKEPFQKLFNQGMILGTSYRD RGALVATDKVEKRDGSFFHVET
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660
            GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  661  LDRVYRLITSKEIVAENNGALDKVYNETVKAVTEQIESMKFNTAIAQLMVFVNAANKEDK  720
            LDRVYRLIT+KEI  EN+GALDKVYNETVKAVTEQ++ MKFNTAIAQLMVFVNAANKEDK
Sbjct  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  721  LYVDYAKGFVQLIAPFAPHLAEELWQTVAATGESISYVAWPTWDESKLVEDEIEIVVQIK  780
            L+ DYAKGFVQLIAPFAPHL+EELWQ+++A+GESISYV+WP+ DESKLVE+++EIVVQIK
Sbjct  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK  780

Query  781  GKVRAKLMVAKDLSRKELQEVALANEKVKAEIDGKEIVKVIAVPNKLVNIVVK  833
            GKV+AKL+VAKDLSR ELQEVALANEKV+AEI GK+I+KVIAVPNKLVNIV+K
Sbjct  781  GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

17) leuS in NC_003485


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1259 bits (4777),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 825/833 (99%), Positives = 831/833 (99%), Gaps = 0/833 (0%)

Query  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60
            MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120
            ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180
            WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANvtfkvkdtd  240
            GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  241  kdftvfttRPDTLFGATYAVLAPEHALVDAITTADQAEAVADYKRQASLKSDLARTDLAK  300
            KDFTVFTTRPDTLFGATYAVLAPEHALVDAITT+DQAEAVADYKRQASLKSDLARTDLAK
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  301  EKTGVWTGSYAINPVNGNEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360
            EKTGVWTGSYAINPVNG+EMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  361  VLEGGNVEEAAFTEDGLHINSGFLDGLDKASAIAKMVEWLEAEGVGNEKVTYRLRDWLFS  420
            VLEGGNVEEAAFTEDGLHINS+FLDGLDKASAIAKMVEWLEAEGVGNE+VTYRLRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480
            RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540
            GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHLET  600
            YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFH+ET
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660
            GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  661  LDRVYRLVTTKEIVAENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720
            LDRVYRL+TTKEI  ENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK
Sbjct  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIk  780
            LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK
Sbjct  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK  780

Query  781  gkvkaklvvakDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833
            GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK
Sbjct  781  GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

18) leuS in NC_015760


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1259 bits (4777),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 757/833 (91%), Positives = 811/833 (98%), Gaps = 0/833 (0%)

Query  1    MSFYNHKEIEPKWQKYWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60
            M+FY+H  IEPKWQ +WADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   ILSRFKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120
            ILSRFKRAQG NVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180
            WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  181  GYPVVRKPMRQWMLKITAYAERLLNDLDELDWPESIKDMQRNWIGKSTGANVTFKVKGTD  240
            GYPVVRKPMRQWMLKITAYAERLL+DL+E+DWPESIKDMQRNWIGKSTGANVTFKVK+TD
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  241  KEFTVFTTRPDTLFGATFTVLAPEHDLVDAITTPEQAEAVADYKHQASLKSDLARTDLAK  300
            K+FTVFTTRPDTLFGAT++VLAPEH LVDAITT++QAEAVADYK+QASLKSDLARTDLAK
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  301  EKTGVWTGAYAINPVNGKEIPIWIADYVLASYGTGAVMAVPAHDERDWEFAKQFDLPIVE  360
            EKTGVWTG+YAINPVNGKE+P+WIADYVLASYGTGA+MAVPAHDERDWEFAKQF+L I+ 
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  361  VLEGGNVEEAAYTEDGLHVNSDFLNGLNKEEAIAKIVAWLEEKGCGQEKVTYRLRDWLFS  420
            VLEGGNVEEAA+TEDGLH+NSDFL+GL+K  AIAK+V WLE  G G+E+VTYRLRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  421  RQRYWGEPIPIVHWEDGTSTAVPESDLPLVLPVTKDIRPSGTGESPLANLTDWLEVTRED  480
            RQRYWGEPIPI+HWEDGTSTAVPES+LPLVLPVTKDIRPSGTGESPLAN+TDWLEVTRED
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEDLLKQWLPVDIYVGGAEHAVLHLL  540
            GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADE+LLKQWLPVDIYVGGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  541  YARFWHKFLYDLGVVPTKEPFQKLFNQGMILGTSYRDHRGALVATDKVEKRDGSFFHMET  600
            YARFWHK LYDLGVVPTKEPFQKLFNQGMILGTSYRD RGALVATDKVEKRDGSFFH+ET
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660
            GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  661  LDRVYRLITTKEIVAENNGTLDKVYNETVKSVTEQVESMKFNTAIAQLMVFVNAANKEDK  720
            LDRVYRLITTKEI  EN+G+LDKVYNETVK+VTEQV+ MKFNTAIAQLMVFVNAANKEDK
Sbjct  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  721  LYVDYAKGFIQLIAPFAPHLAEELWQTVAETGESISYVAWPTWDESKLVEDEIEIVVQIK  780
            L+ DYAKGF+QLIAPFAPHL+EELWQ+++ +GESISYV+WP+ DESKLVE+++EIVVQIK
Sbjct  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK  780

Query  781  GKVRAKLMVAKDLSREELQEVALANEKVKAEIDGKEIVKVISVPNKLVNIVVK  833
            GKV+AKL+VAKDLSREELQEVALANEKV+AEI GK+I+KVI+VPNKLVNIV+K
Sbjct  781  GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

19) leuS in NC_017040


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1257 bits (4769),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 823/833 (99%), Positives = 831/833 (99%), Gaps = 0/833 (0%)

Query  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60
            MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120
            ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180
            WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANvtfkvkdtd  240
            GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  241  kdftvfttRPDTLFGATYAVLAPEHALVDAITTADQAEAVAEYKRQASLKSDLARTDLAK  300
            KDFTVFTTRPDTLFGATYAVLAPEHALVDAITT+DQAEAVA+YKRQASLKSDLARTDLAK
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  301  EKTGVWTGSYAINPVNGNKMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360
            EKTGVWTGSYAINPVNG+ MPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  361  VLEGGNVEEAAFTEDGLHINSGFLDGLDKASAIAKMVEWLEAEGVGNEKVTYRLRDWLFS  420
            VLEGGNVEEAAFTEDGLHINS+FLDGLDKASAIAKMVEWLEAEGVGNE+VTYRLRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480
            RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540
            GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGTLVATDKVEKRDGSFFHVET  600
            YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRG+LVATDKVEKRDGSFFHVET
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRRF  660
            GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSR+F
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  661  LDRVHRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720
            LDRV RLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK
Sbjct  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  721  LFSDYAKGFVQLVAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIk  780
            LFSDYAKGFVQL+APFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK
Sbjct  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK  780

Query  781  gkvkaklvvakDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833
            GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK
Sbjct  781  GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

20) leuS in NC_017053


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1257 bits (4769),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 823/833 (99%), Positives = 831/833 (99%), Gaps = 0/833 (0%)

Query  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60
            MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120
            ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180
            WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANvtfkvkdtd  240
            GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  241  kdftvfttRPDTLFGATYAVLAPEHALVDAITTADQAEAVAEYKRQASLKSDLARTDLAK  300
            KDFTVFTTRPDTLFGATYAVLAPEHALVDAITT+DQAEAVA+YKRQASLKSDLARTDLAK
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  301  EKTGVWTGSYAINPVNGNKMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360
            EKTGVWTGSYAINPVNG+ MPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  361  VLEGGNVEEAAFTEDGLHINSGFLDGLDKASAIAKMVEWLEAEGVGNEKVTYRLRDWLFS  420
            VLEGGNVEEAAFTEDGLHINS+FLDGLDKASAIAKMVEWLEAEGVGNE+VTYRLRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480
            RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540
            GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGTLVATDKVEKRDGSFFHVET  600
            YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRG+LVATDKVEKRDGSFFHVET
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRRF  660
            GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSR+F
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  661  LDRVHRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720
            LDRV RLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK
Sbjct  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  721  LFSDYAKGFVQLVAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIk  780
            LFSDYAKGFVQL+APFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK
Sbjct  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK  780

Query  781  gkvkaklvvakDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833
            GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK
Sbjct  781  GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

21) leuS in NC_010380


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1257 bits (4769),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 754/833 (91%), Positives = 812/833 (98%), Gaps = 0/833 (0%)

Query  1    MSFYNHKEIEPKWQGYWAEHHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60
            M+FY+H  IEPKWQ++WA++HTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   ILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120
            ILSR+KRAQG NVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180
            WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  181  GYPVVRKPMRQWMLKITAYAERLLNDLDELDWPESIKDMQRNWIGKSTGANVTFKVKGTD  240
            GYPVVRKPMRQWMLKITAYAERLL+DL+E+DWPESIKDMQRNWIGKSTGANVTFKVK+TD
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  241  KEFTVFTTRPDTLFGATFTVLAPEHELVDAITSTEQAEAVADYKHQASLKSDLARTDLAK  300
            K+FTVFTTRPDTLFGAT++VLAPEH LVDAIT+++QAEAVADYK+QASLKSDLARTDLAK
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  301  EKTGVWTGAYAINPVNGKEIPIWIADYVLASYGTGAVMAVPAHDQRDWEFAKQFDLPIVE  360
            EKTGVWTG+YAINPVNGKE+P+WIADYVLASYGTGA+MAVPAHD+RDWEFAKQF+L I+ 
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  361  VLEGGNVEEAAYTEDGLHVNSDFLDGLNKEDAIAKIVAWLEEKGCGQEKVTYRLRDWLFS  420
            VLEGGNVEEAA+TEDGLH+NSDFLDGL+K  AIAK+V WLE  G G+E+VTYRLRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANLTDWLEVTRED  480
            RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLAN+TDWLEVTRED
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEDLLKQWLPVDIYVGGAEHAVLHLL  540
            GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADE+LLKQWLPVDIYVGGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  541  YARFWHKFLYDLGVVPTKEPFQKLFNQGMILGTSYRDHRGALVATDKVEKRDGSFFHVET  600
            YARFWHK LYDLGVVPTKEPFQKLFNQGMILGTSYRD RGALVATDKVEKRDGSFFHVET
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660
            GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  661  LDRVYRLITSKEILAENNGALDKVYNETVKAVTEQIESLKFNTAIAQLMVFVNAANKEDK  720
            LDRVYRLIT+KEI  EN+GALDKVYNETVKAVTEQ++ +KFNTAIAQLMVFVNAANKEDK
Sbjct  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  721  LYVDYAKGFIQLIAPFAPHLAEELWQTVAETGESISYVAWPTWDESKLVEDEIEIVVQIK  780
            L+ DYAKGF+QLIAPFAPHL+EELWQ+++ +GESISYV+WP+ DESKLVE+++EIVVQIK
Sbjct  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK  780

Query  781  GKVRAKLMVAKDLSREELQEIALADEKVKAEIDGKEIVKVIAVPNKLVNIVVK  833
            GKV+AKL+VAKDLSREELQE+ALA+EKV+AEI GK+I+KVIAVPNKLVNIV+K
Sbjct  781  GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

22) leuS in NC_003028


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1257 bits (4770),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 753/833 (91%), Positives = 812/833 (98%), Gaps = 0/833 (0%)

Query  1    MSFYNHKEIEPKWQGYWAEHHTFKTGTDTSKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60
            M+FY+H  IEPKWQ++WA++HTFKTGTD+SKPKFYALDMFPYPSGAGLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   ILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120
            ILSR+KRAQG NVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180
            WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  181  GYPVVRKPMRQWMLKITAYAERLLNDLDELDWSESIKDMQRNWIGKSTGANVTFKVKGTD  240
            GYPVVRKPMRQWMLKITAYAERLL+DL+E+DW+ESIKDMQRNWIGKSTGANVTFKVK+TD
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  241  KEFTVFTTRPDTLFGATFTVLAPEHELVDAITSSEQAEAVADYKHQASLKSDLARTDLAK  300
            K+FTVFTTRPDTLFGAT++VLAPEH LVDAIT+S+QAEAVADYK+QASLKSDLARTDLAK
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  301  EKTGVWTGAYAINPVNGKEMPIWIADYVLASYGTGAVMAVPAHDQRDWEFAKQFDLPIVE  360
            EKTGVWTG+YAINPVNGKEMP+WIADYVLASYGTGA+MAVPAHD+RDWEFAKQF+L I+ 
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  361  VLEGGNVEEAAYTEDGLHVNSDFLDGLNKEDAIAKIVAWLEEKGCGQEKVTYRLRDWLFS  420
            VLEGGNVEEAA+TEDGLH+NSDFLDGL+K  AIAK+V WLE  G G+E+VTYRLRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  421  RQRYWGEPIPIIHWEDGTSTAVPETELPLVLPVTKDIRPSGTGESPLANLTDWLEVTRED  480
            RQRYWGEPIPIIHWEDGTSTAVPE+ELPLVLPVTKDIRPSGTGESPLAN+TDWLEVTRED
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEDLLKQWLPVDIYVGGAEHAVLHLL  540
            GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADE+LLKQWLPVDIYVGGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  541  YARFWHKFLYDLGVVPTKEPFQKLFNQGMILGTSYRDHRGALVATDKVEKRDGSFFHVET  600
            YARFWHK LYDLGVVPTKEPFQKLFNQGMILGTSYRD RGALVATDKVEKRDGSFFHVET
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660
            GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  661  LDRVYRLITSKEILAENNGALDKVYNETVKAVTEQIESLKFNTAIAQLMVFVNAANKEDK  720
            LDRVYRLIT+KEI  EN+GALDKVYNETVKAVTEQ++ +KFNTAIAQLMVFVNAANKEDK
Sbjct  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  721  LYVDYAKGFIQLIAPFAPHLAEELWQTVAETGESISYVAWPTWDESKLVEDEIEIVVQIK  780
            L+ DYAKGF+QLIAPFAPHL+EELWQ+++ +GESISYV+WP+ DESKLVE+++EIVVQIK
Sbjct  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK  780

Query  781  GKVRAKLMVAKDLSREELQEIALADEKVKAEIDGKEIVKVIAVPNKLVNIVVK  833
            GKV+AKL+VAKDLSREELQE+ALA+EKV+AEI GK+I+KVIAVPNKLVNIV+K
Sbjct  781  GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

23) leuS in NC_017595


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1257 bits (4769),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 754/833 (91%), Positives = 811/833 (98%), Gaps = 0/833 (0%)

Query  1    MSFYNHKEIEPKWQKYWADHHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60
            M+FY+H  IEPKWQ +WAD+HTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   ILSRFKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120
            ILSRFKRAQG NVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180
            WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  181  GYPVVRKPMRQWMLKITAYAERLLNDLDDLDWPESIKDMQRNWIGKSTGANVTFKVKGTD  240
            GYPVVRKPMRQWMLKITAYAERLL+DL+++DWPESIKDMQRNWIGKSTGANVTFKVK+TD
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  241  KEFTVFTTRPDTLFGATFTVLAPEHDLVDAITTPEQAEAVADYKHQASLKSDLARTDLAK  300
            K+FTVFTTRPDTLFGAT++VLAPEH LVDAITT++QAEAVADYK+QASLKSDLARTDLAK
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  301  EKTGVWTGAYAVNPVNGKEIPIWIADYVLASYGTGAVMAVPAHDERDWEFAKQFDLPIVE  360
            EKTGVWTG+YA+NPVNGKE+P+WIADYVLASYGTGA+MAVPAHDERDWEFAKQF+L I+ 
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  361  VLEGGNVEEAAYTEDGLHVNSDFLNGLNKEEAIAKIVAWLEEKGFGQEKITYRLRDWLFS  420
            VLEGGNVEEAA+TEDGLH+NSDFL+GL+K  AIAK+V WLE  G G+E++TYRLRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANLTDWLEVTRED  480
            RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLAN+TDWLEVTRED
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEDLLKQWLPVDIYVGGAEHAVLHLL  540
            GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADE+LLKQWLPVDIYVGGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  541  YARFWHKFLYDLGVVPTKEPFQKLFNQGMILGTSYRDHRGALVATDKVEKRDGSFFHVET  600
            YARFWHK LYDLGVVPTKEPFQKLFNQGMILGTSYRD RGALVATDKVEKRDGSFFHVET
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660
            GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  661  LDRVYRLITSKEIVAENNGALDKVYNETVKSVTEQIEAMKFNTAIAQLMVFVNAANKEDK  720
            LDRVYRLIT+KEI  EN+GALDKVYNETVK+VTEQ++ MKFNTAIAQLMVFVNAANKEDK
Sbjct  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  721  LYVDYAKGFIQLIAPFAPHLAEELWQTVAETGESISYVAWPTWDESKLVEDEIEIVVQIK  780
            L+ DYAKGF+QLIAPFAPHL+EELWQ+++ +GESISYV+WP+ DESKLVE+++EIVVQIK
Sbjct  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK  780

Query  781  GKVRAKLMVAKDLSREELQEVALADDKVKAEIEGKEIVKVIAVPNKLVNIVVK  833
            GKV+AKL+VAKDLSREELQEVALA++KV+AEI GK+I+KVIAVPNKLVNIV+K
Sbjct  781  GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

24) leuS in NC_004116


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1256 bits (4765),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 816/833 (98%), Positives = 830/833 (99%), Gaps = 0/833 (0%)

Query  1    MTFYNHKEIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60
            MTFY+H  IEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120
            ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180
            WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANvtfkvkdtd  240
            GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  241  kdftvfttRPDTLFGATYAVLAPEHALVDAITTADQAEAVAEYKRQASLKSDLARTDLAK  300
            KDFTVFTTRPDTLFGATYAVLAPEHALVDAITT+DQAEAVA+YKRQASLKSDLARTDLAK
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  301  EKTGVWTGAYAINPVNGKEIPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360
            EKTGVWTG+YAINPVNGKE+PVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKAAAIAKMVEWLEAEGVGNEKVTYRLRDWLFS  420
            VLEGGNVEEAAFTEDGLHINSDFLDGLDKA+AIAKMVEWLEAEGVGNE+VTYRLRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANLTDWLEVTRED  480
            RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLAN+TDWLEVTRED
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540
            GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600
            YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660
            GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720
            LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK
Sbjct  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  721  LFSDYAKGFVQLIAPFAPHLGEELWQVLTASGQSISYVPWPSYDESKLVENEIEIVVQIk  780
            LFSDYAKGFVQLIAPFAPHLGEELWQ LTASG+SISYVPWPSYDESKLVEN++EIVVQIK
Sbjct  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK  780

Query  781  gkvkaklvvakDLSREELQDLALANEKVQAEIAGKDIIKVIAVPNKLVNIVVK  833
            GKVKAKLVVAKDLSREELQ++ALANEKVQAEIAGKDIIKVIAVPNKLVNIV+K
Sbjct  781  GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

25) leuS in NC_004368


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1256 bits (4765),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 816/833 (98%), Positives = 830/833 (99%), Gaps = 0/833 (0%)

Query  1    MTFYNHKEIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60
            MTFY+H  IEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120
            ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180
            WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANvtfkvkdtd  240
            GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  241  kdftvfttRPDTLFGATYAVLAPEHALVDAITTADQAEAVAEYKRQASLKSDLARTDLAK  300
            KDFTVFTTRPDTLFGATYAVLAPEHALVDAITT+DQAEAVA+YKRQASLKSDLARTDLAK
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  301  EKTGVWTGAYAINPVNGKEIPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360
            EKTGVWTG+YAINPVNGKE+PVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKAAAIAKMVEWLEAEGVGNEKVTYRLRDWLFS  420
            VLEGGNVEEAAFTEDGLHINSDFLDGLDKA+AIAKMVEWLEAEGVGNE+VTYRLRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANLTDWLEVTRED  480
            RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLAN+TDWLEVTRED
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540
            GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600
            YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660
            GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720
            LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK
Sbjct  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  721  LFSDYAKGFVQLIAPFAPHLGEELWQVLTASGQSISYVPWPSYDESKLVENEIEIVVQIk  780
            LFSDYAKGFVQLIAPFAPHLGEELWQ LTASG+SISYVPWPSYDESKLVEN++EIVVQIK
Sbjct  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK  780

Query  781  gkvkaklvvakDLSREELQDLALANEKVQAEIAGKDIIKVIAVPNKLVNIVVK  833
            GKVKAKLVVAKDLSREELQ++ALANEKVQAEIAGKDIIKVIAVPNKLVNIV+K
Sbjct  781  GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

26) leuS in NC_015678


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1256 bits (4766),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 755/833 (91%), Positives = 811/833 (98%), Gaps = 0/833 (0%)

Query  1    MSFYNHKEIEPKWQKYWADHHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60
            M+FY+H  IEPKWQ +WAD+HTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   ILSRFKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120
            ILSRFKRAQG NVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180
            WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  181  GYPVVRKPMRQWMLKITAYAERLLNDLDDLDWPESIKDMQRNWIGKSTGANVTFKVKGTD  240
            GYPVVRKPMRQWMLKITAYAERLL+DL+++DWPESIKDMQRNWIGKSTGANVTFKVK+TD
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  241  KEFTVFTTRPDTLFGATFTVLAPEHELVDAITTPEQAEAVADYKHQASLKSDLARTDLAK  300
            K+FTVFTTRPDTLFGAT++VLAPEH LVDAITT++QAEAVADYK+QASLKSDLARTDLAK
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  301  EKTGVWTGAYAINPVNGKEIPIWIADYVLASYGTGAVMAVPAHDERDWEFAKQFGLPIVE  360
            EKTGVWTG+YAINPVNGKE+P+WIADYVLASYGTGA+MAVPAHDERDWEFAKQF L I+ 
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  361  VLEGGNVEEAAYTEDGLHVNSDFLNGLNKEEAIAKIVSWLEEKGFGQEKVTYRLRDWLFS  420
            VLEGGNVEEAA+TEDGLH+NSDFL+GL+K  AIAK+V WLE  G G+E+VTYRLRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANLTDWLEVTRED  480
            RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLAN+TDWLEVTRED
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEDLLKQWLPVDIYVGGAEHAVLHLL  540
            GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADE+LLKQWLPVDIYVGGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  541  YARFWHKFLYDLDVVPTKEPFQKLFNQGMILGTSYRDHRGALVATDKVEKRDGSFFHVET  600
            YARFWHK LYDL+VVPTKEPFQKLFNQGMILGTSYRD RGALVATDKVEKRDGSFFHVET
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660
            GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  661  LDRVYRLITSKEIVAENNGALDKVYNETVKSVTEQIESMKFNTAIAQLMVFVNAANKEDK  720
            LDRVYRLIT+KEI  EN+GALDKVYNETVK+VTEQ++ MKFNTAIAQLMVFVNAANKEDK
Sbjct  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  721  LYVDYAKGFIQLIAPFAPHLAEELWQTVAATGESISYVAWPTWDESKLVEDEIEIVVQIK  780
            L+ DYAKGF+QLIAPFAPHL+EELWQ+++A+GESISYV+WP+ DESKLVE+++EIVVQIK
Sbjct  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK  780

Query  781  GKVRAKLMVAKDLSREELQEVALADEKVKAEIDGKEVVKVISVPNKLVNIVVK  833
            GKV+AKL+VAKDLSREELQEVALA+EKV+AEI GK+++KVI+VPNKLVNIV+K
Sbjct  781  GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

27) leuS in NC_017591


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1256 bits (4764),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 753/833 (91%), Positives = 811/833 (98%), Gaps = 0/833 (0%)

Query  1    MSFYNHKEIEPKWQGYWAEHHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60
            M+FY+H  IEPKWQ++WA++HTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   ILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120
            ILSR+KRAQG NVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180
            WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  181  GYPVVRKPMRQWMLKITAYAERLLNDLDELDWSESIKDMQRNWIGKSTGANVTFKVKGTD  240
            GYPVVRKPMRQWMLKITAYAERLL+DL+E+DW+ESIKDMQRNWIGKSTGANVTFKVK+TD
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  241  KEFTVFTTRPDTLFGATFTVLAPEHELVDAITSTEQAEAVADYKHQASLKSDLARTDLAK  300
            K+FTVFTTRPDTLFGAT++VLAPEH LVDAIT+++QAEAVADYK+QASLKSDLARTDLAK
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  301  EKTGVWTGAYAINPVNGKEIPIWIADYVLASYGTGAVMAVPAHDQRDWEFAKQFDLPIVE  360
            EKTGVWTG+YAINPVNGKE+P+WIADYVLASYGTGA+MAVPAHD+RDWEFAKQF+L I+ 
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  361  VLEGGNVEEAAYTEDGLHVNSDFLDGLNKEDAIAKIVAWLEEKGCGQEKVTYRLRDWLFS  420
            VLEGGNVEEAA+TEDGLH+NSDFLDGL+K  AIAK+V WLE  G G+E+VTYRLRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANLTDWLEVTRED  480
            RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLAN+TDWLEVTRED
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEDLLKQWLPVDIYVGGAEHAVLHLL  540
            GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADE+LLKQWLPVDIYVGGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  541  YARFWHKFLYDLGVVPTKEPFQKLFNQGMILGTSYRDHRGALVATDKVEKRDGSFFHVET  600
            YARFWHK LYDLGVVPTKEPFQKLFNQGMILGTSYRD RGALVATDKVEKRDGSFFHVET
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660
            GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  661  LDRVYRLIRSKEIVAENNGALDKVYNETVKAVTEQIDSLKFNTAIAQLMVFVNAANKEDK  720
            LDRVYRLI +KEI  EN+GALDKVYNETVKAVTEQ+D +KFNTAIAQLMVFVNAANKEDK
Sbjct  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  721  LYVDYAKGFIQLIAPFAPHLAEELWQTVAATGESISYVTWPTWDESKLVEDEIEIVVQIK  780
            L+ DYAKGF+QLIAPFAPHL+EELWQ+++A+GESISYV WP+ DESKLVE+++EIVVQIK
Sbjct  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK  780

Query  781  GKVRAKLMVAKDLSREELQEIALADEKVKAEIDGKEIVKVISVPNKLVNIVVK  833
            GKV+AKL+VAKDLSREELQE+ALA+EKV+AEI GK+I+KVI+VPNKLVNIV+K
Sbjct  781  GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

28) Ssal_01962 in NC_017594


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1256 bits (4763),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 755/833 (91%), Positives = 810/833 (98%), Gaps = 0/833 (0%)

Query  1    MSFYNHKEIEPKWQKYWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60
            M+FY+H  IEPKWQ +WADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   ILSRFKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120
            ILSRFKRAQG NVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180
            WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  181  GYPVVRKPMRQWMLKITAYAERLLNDLDDLDWPESIKDMQRNWIGKSTGANVTFKVKGID  240
            GYPVVRKPMRQWMLKITAYAERLL+DL+++DWPESIKDMQRNWIGKSTGANVTFKVK+ D
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  241  KEFTVFTTRPDTLFGATFTVLAPEHDLVDAITTPEQAEAVADYKHQASLKSDLARTDLAK  300
            K+FTVFTTRPDTLFGAT++VLAPEH LVDAITT++QAEAVADYK+QASLKSDLARTDLAK
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  301  EKTGVWTGAYAINPVNGKEIPIWIADYVLASYGTGAVMAVPAHDERDWEFAKQFDLPIVE  360
            EKTGVWTG+YAINPVNGKE+P+WIADYVLASYGTGA+MAVPAHDERDWEFAKQF+L I+ 
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  361  VLEGGNVEEAAYTEDGLHVNSDFLNGLNKEEAIAKIVAWLEEKGFGQEKITYRLRDWLFS  420
            VLEGGNVEEAA+TEDGLH+NSDFL+GL+K  AIAK+V WLE  G G+E++TYRLRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANLTDWLEVTRED  480
            RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLAN+TDWLEVTRED
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEDLLKQWLPVDIYVGGAEHAVLHLL  540
            GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADE+LLKQWLPVDIYVGGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  541  YARFWHKFLYDLGVVPTKEPFQKLFNQGMILGTSYRDHRGALVATDKVEKRDGSFFHVET  600
            YARFWHK LYDLGVVPTKEPFQKLFNQGMILGTSYRD RGALVATDKVEKRDGSFFHVET
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660
            GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  661  LDRVYRLITSKEIVAENNGALDKVYNETVKSVTEQIESMKFNTAIAQLMVFVNAANKEDK  720
            LDRVYRLIT+KEI  EN+GALDKVYNETVK+VTEQ++ MKFNTAIAQLMVFVNAANKEDK
Sbjct  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  721  LYVGYAKGFIQLIAPFAPHLAEELWQTVAETGESISYIAWPTWDESKLVEDEIEIVVQIK  780
            L+ +YAKGF+QLIAPFAPHL+EELWQ+++ +GESISY++WP+ DESKLVE+++EIVVQIK
Sbjct  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK  780

Query  781  GKVRAKLMVAKDLSREELQEVALANEKVKAEIDGKEIVKVIAVPNKLVNIVVK  833
            GKV+AKL+VAKDLSREELQEVALANEKV+AEI GK+I+KVIAVPNKLVNIV+K
Sbjct  781  GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

29) BSA_20450 in NC_021485


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1255 bits (4760),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 815/833 (98%), Positives = 829/833 (99%), Gaps = 0/833 (0%)

Query  1    MTFYNHKEIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60
            MTFY+H  IEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120
            ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180
            WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANvtfkvkdtd  240
            GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  241  kdftvfttRPDTLFGATYAVLAPEHALVDAITTADQAEAVAEYKRQASLKSDLARTDLAK  300
            KDFTVFTTRPDTLFGATYAVLAPEHALVDAITT+DQAEAVA+YKRQASLKSDLARTDLAK
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  301  EKTGVWTGAYAINPVNGKEIPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFKLDIIP  360
            EKTGVWTG+YAINPVNGKE+PVWIADYVLASYGTGAIMAVPAHDERDWEFAKQF+LDIIP
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNEKVTYRLRDWLFS  420
            VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNE+VTYRLRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANLTDWLEVTRED  480
            RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLAN+TDWLEVTRED
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540
            GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600
            YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660
            GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  661  LDRVYRLITTKEITKENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720
            LDRVYRLITTKEIT ENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK
Sbjct  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  721  LFSDYAKGFVQLIAPFAPHLGEELWQVLTASGESISYVPWPSYDESKLVENEIEIVVQIk  780
            LFSDYAKGFVQLIAPFAPHLGEELWQ LTASGESISYVPWPSYDESKLVEN++EIVVQIK
Sbjct  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK  780

Query  781  gkvkaklvvakDLSREELQDLALANEKVQSEIAGKDIIKVIAVPNKLVNIVVK  833
            GKVKAKLVVAKDLSREELQ++ALANEKVQ+EIAGKDIIKVIAVPNKLVNIV+K
Sbjct  781  GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

30) leuS in NC_007432


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1255 bits (4760),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 815/833 (98%), Positives = 829/833 (99%), Gaps = 0/833 (0%)

Query  1    MTFYNHKEIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60
            MTFY+H  IEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120
            ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180
            WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANvtfkvkdtd  240
            GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  241  kdftvfttRPDTLFGATYAVLAPEHALVDAITTADQAEAVAEYKRQASLKSDLARTDLAK  300
            KDFTVFTTRPDTLFGATYAVLAPEHALVDAITT+DQAEAVA+YKRQASLKSDLARTDLAK
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  301  EKTGVWTGAYAINPVNGKEIPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFKLDIIP  360
            EKTGVWTG+YAINPVNGKE+PVWIADYVLASYGTGAIMAVPAHDERDWEFAKQF+LDIIP
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNEKVTYRLRDWLFS  420
            VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNE+VTYRLRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANLTDWLEVTRED  480
            RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLAN+TDWLEVTRED
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540
            GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600
            YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660
            GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  661  LDRVYRLITTKEITKENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720
            LDRVYRLITTKEIT ENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK
Sbjct  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  721  LFSDYAKGFVQLIAPFAPHLGEELWQVLTASGESISYVPWPSYDESKLVENEIEIVVQIk  780
            LFSDYAKGFVQLIAPFAPHLGEELWQ LTASGESISYVPWPSYDESKLVEN++EIVVQIK
Sbjct  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK  780

Query  781  gkvkaklvvakDLSREELQDLALANEKVQSEIAGKDIIKVIAVPNKLVNIVVK  833
            GKVKAKLVVAKDLSREELQ++ALANEKVQ+EIAGKDIIKVIAVPNKLVNIV+K
Sbjct  781  GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

31) leuS in NC_018646


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1255 bits (4760),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 815/833 (98%), Positives = 829/833 (99%), Gaps = 0/833 (0%)

Query  1    MTFYNHKEIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60
            MTFY+H  IEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120
            ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180
            WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANvtfkvkdtd  240
            GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  241  kdftvfttRPDTLFGATYAVLAPEHALVDAITTADQAEAVAEYKRQASLKSDLARTDLAK  300
            KDFTVFTTRPDTLFGATYAVLAPEHALVDAITT+DQAEAVA+YKRQASLKSDLARTDLAK
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  301  EKTGVWTGAYAINPVNGKEIPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFKLDIIP  360
            EKTGVWTG+YAINPVNGKE+PVWIADYVLASYGTGAIMAVPAHDERDWEFAKQF+LDIIP
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNEKVTYRLRDWLFS  420
            VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNE+VTYRLRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANLTDWLEVTRED  480
            RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLAN+TDWLEVTRED
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540
            GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600
            YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660
            GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  661  LDRVYRLITTKEITKENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720
            LDRVYRLITTKEIT ENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK
Sbjct  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  721  LFSDYAKGFVQLIAPFAPHLGEELWQVLTASGESISYVPWPSYDESKLVENEIEIVVQIk  780
            LFSDYAKGFVQLIAPFAPHLGEELWQ LTASGESISYVPWPSYDESKLVEN++EIVVQIK
Sbjct  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK  780

Query  781  gkvkaklvvakDLSREELQDLALANEKVQSEIAGKDIIKVIAVPNKLVNIVVK  833
            GKVKAKLVVAKDLSREELQ++ALANEKVQ+EIAGKDIIKVIAVPNKLVNIV+K
Sbjct  781  GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

32) leuS in NC_019048


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1255 bits (4761),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 815/833 (98%), Positives = 829/833 (99%), Gaps = 0/833 (0%)

Query  1    MTFYNHKEIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60
            MTFY+H  IEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120
            ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180
            WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSIGANvtfkvkdtd  240
            GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKS GANVTFKVKDTD
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  241  kdftvfttRPDTLFGATYAVLAPEHALVDAITTADQAEAVAEYKRQASLKSDLARTDLAK  300
            KDFTVFTTRPDTLFGATYAVLAPEHALVDAITT+DQAEAVA+YKRQASLKSDLARTDLAK
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  301  EKTGVWTGAYAINPVNGKEIPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360
            EKTGVWTG+YAINPVNGKE+PVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKAAAIAKMVEWLEAEGVGNEKVTYRLRDWLFS  420
            VLEGGNVEEAAFTEDGLHINSDFLDGLDKA+AIAKMVEWLEAEGVGNE+VTYRLRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANLTDWLEVTRED  480
            RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLAN+TDWLEVTRED
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540
            GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600
            YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660
            GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720
            LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK
Sbjct  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  721  LFSDYAKGFVQLIAPFAPHLGEELWQVLTASGQSISYVPWPSYDESKLVENEIEIVVQIk  780
            LFSDYAKGFVQLIAPFAPHLGEELWQ LTASG+SISYVPWPSYDESKLVEN++EIVVQIK
Sbjct  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK  780

Query  781  gkvkaklvvakDLSREELQDLALANEKVQAEIAGKDIIKVIAVPNKLVNIVVK  833
            GKVKAKLVVAKDLSREELQ++ALANEKVQAEIAGKDIIKVIAVPNKLVNIV+K
Sbjct  781  GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

33) leuS in NC_015291


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1255 bits (4761),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 751/833 (91%), Positives = 810/833 (98%), Gaps = 0/833 (0%)

Query  1    MSFYNHKEIEHKWQGYWAQHHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60
            M+FY+H  IE KWQ++WA++HTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   ILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120
            ILSR+KRAQG NVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180
            WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  181  GYPVVRKPMRQWMLKITAYAERLLNDLDELDWPESIKDMQRNWIGKSTGANVTFKVKGTD  240
            GYPVVRKPMRQWMLKITAYAERLL+DL+E+DWPESIKDMQRNWIGKSTGANVTFKVK+TD
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  241  KEFTVFTTRPDTLFGATFTVLAPEHDLVDAIVSPEQAEAVADYKHQASLKSDLARTDLAK  300
            K+FTVFTTRPDTLFGAT++VLAPEH LVDAI +++QAEAVADYK+QASLKSDLARTDLAK
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  301  EKTGVWTGAYAINPVNGKEIPIWIADYVLASYGTGAVMAVPAHDQRDWEFAKQFDLPIVE  360
            EKTGVWTG+YAINPVNGKE+P+WIADYVLASYGTGA+MAVPAHD+RDWEFAKQF+L I+ 
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  361  VLEGGNVAEAAYTEDGLHVNSDFLDGLNKEEAIAKIVAWLEEKGCGQEKVTYRLRDWLFS  420
            VLEGGNV EAA+TEDGLH+NSDFLDGL+K  AIAK+V WLE  G G+E+VTYRLRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANLADWLEVTRED  480
            RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLAN++DWLEVTRED
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEDLLKQWLPVDIYVGGAEHAVLHLL  540
            GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADE+LLKQWLPVDIYVGGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  541  YARFWHKFLYDLGVVPTKEPFQKLFNQGMILGTSYRDHRGALVATDKVEKRDGSFFHVET  600
            YARFWHK LYDLGVVPTKEPFQKLFNQGMILGTSYRD RGALVATDKVEKRDGSFFHVET
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660
            GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  661  LDRVYRLITSKEIVAENNGALDKVYNETVKSVTEQIESMKFNTAIAQLMVFVNAANKEDK  720
            LDRVYRLIT+KEI  EN+GALDKVYNETVK+VTEQ++ MKFNTAIAQLMVFVNAANKEDK
Sbjct  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  721  LYVDYAKGFIQLIAPFAPHLAEELWQTVAATGESISYVAWPTWDESKLVEDEIEIVVQIK  780
            L+ DYAKGF+QLIAPFAPHL+EELWQ+++A+GESISYV+WP+ DESKLVE+++EIVVQIK
Sbjct  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK  780

Query  781  GKVRAKLMVAKDLSREELQEIALADEKVKAEIDGKEIVKVIAVPNKLVNIVVK  833
            GKV+AKL+VAKDLSREELQE+ALA+EKV+AEI GK+I+KVIAVPNKLVNIV+K
Sbjct  781  GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

34) MSA_21140 in NC_021486


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1254 bits (4757),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 817/833 (99%), Positives = 829/833 (99%), Gaps = 0/833 (0%)

Query  1    MTFYNHKEIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60
            MTFY+H  IEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120
            ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180
            WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANvtfkvkdtd  240
            GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  241  kdftvfttRPDTLFGATYAVLAPEHALVDAITTADQAEAVAEYKRQASLKSDLARTDLAK  300
            KDFTVFTTRPDTLFGATYAVLAPEHALVDAITT+DQAEAVA+YKRQASLKSDLARTDLAK
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  301  EKTGVWTGAYAINPVNGKEIPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360
            EKTGVWTG+YAINPVNGKE+PVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  361  VLEGGNVEEAALTEDGLHINSGFLDGLDKASAIAKMVEWLEAEGVGNEKVTYRLRDWLFS  420
            VLEGGNVEEAA+TEDGLHINS+FLDGLDKASAIAKMVEWLEAEGVGNE+VTYRLRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANLTDWLEVTRED  480
            RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLAN+TDWLEVTRED
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540
            GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600
            YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660
            GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720
            LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK
Sbjct  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  721  LFSDYAKGFVQLIAPFAPHLGEELWQVLTASGESISYVPWPSYDESKLVENEIEIVVQIk  780
            LFSDYAKGFVQLIAPFAPHLGEELWQ LTASGESISYVPWPSYDESKLVEN++EIVVQIK
Sbjct  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK  780

Query  781  gkvkaklvvakDLSREELQEVALANEKVQAEIAGKDIIKVIVVPNKLVNIVVK  833
            GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVI VPNKLVNIV+K
Sbjct  781  GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

35) SAIL_20620 in NC_021507


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1254 bits (4759),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 817/833 (99%), Positives = 830/833 (99%), Gaps = 0/833 (0%)

Query  1    MTFYNHKEIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60
            MTFY+H  IEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120
            ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180
            WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANvtfkvkdtd  240
            GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  241  kdftvfttRPDTLFGATYAVLAPEHALVDAITTADQAEAVAEYKRQASLKSDLARTDLAK  300
            KDFTVFTTRPDTLFGATYAVLAPEHALVDAITT+DQAEAVA+YKRQASLKSDLARTDLAK
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  301  EKTGVWTGAYAINPVNGKEIPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFKLDIIP  360
            EKTGVWTG+YAINPVNGKE+PVWIADYVLASYGTGAIMAVPAHDERDWEFAKQF+LDIIP
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNEKVTYRLRDWLFS  420
            VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNE+VTYRLRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANLTDWLEVTRED  480
            RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLAN+TDWLEVTRED
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540
            GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600
            YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660
            GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720
            LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK
Sbjct  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  721  LFSDYAKGFVQLIAPFAPHLGEELWQVLTASGESISYVPWPSYDESKLVENEIEIVVQIk  780
            LFSDYAKGFVQLIAPFAPHLGEELWQ LTASGESISYVPWPSYDESKLVEN++EIVVQIK
Sbjct  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK  780

Query  781  gkvkaklvvakDFSREELQELALANEKVQAEIAGKDIIKVIAVPNKLVNIVVK  833
            GKVKAKLVVAKD+SREELQE+ALANEKVQAEIAGKDIIKVIAVPNKLVNIV+K
Sbjct  781  GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

36) leuS in NC_006449


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1254 bits (4757),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 754/833 (91%), Positives = 810/833 (98%), Gaps = 0/833 (0%)

Query  1    MSFYNHKEIEPKWQKYWADHHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60
            M+FY+H  IEPKWQ +WAD+HTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   ILSRFKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPADFTAENIANFKRQINALGFSYD  120
            ILSRFKRAQG NVLHPMGWDAFGLPAEQYAMDTGNDPA+FTAENIANFKRQINALGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WDREINTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180
            WDRE+NTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  181  GYPVVRKPMRQWMLKITAYAERLLNDLDELDWPESIKDMQRNWIGKSTGANVTFKVKGTD  240
            GYPVVRKPMRQWMLKITAYAERLL+DL+E+DWPESIKDMQRNWIGKSTGANVTFKVK+TD
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  241  KEFTVFTTRPDTLFGATFTVLAPEHDLVDAITSPEQAEAVANYKHQASLKSDLARTDLAK  300
            K+FTVFTTRPDTLFGAT++VLAPEH LVDAIT+++QAEAVA+YK+QASLKSDLARTDLAK
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  301  EKTGVWTGAYAINPVNGREIPIWIADYVLASYGTGAVMAVPAHDERDWEFAKQFGLPIVE  360
            EKTGVWTG+YAINPVNG+E+P+WIADYVLASYGTGA+MAVPAHDERDWEFAKQF L I+ 
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  361  VLEGGNVEEAAYTEDGPHVNSDFLNGLNKEEAIAKIVAWLEEKGFGQEKITYRLRDWLFS  420
            VLEGGNVEEAA+TEDG H+NSDFL+GL+K  AIAK+V WLE  G G+E++TYRLRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANLTDWLEVTRED  480
            RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLAN+TDWLEVTRED
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEDLLKQWLPVDIYVGGAEHAVLHLL  540
            GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADE+LLKQWLPVDIYVGGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  541  YARFWHKFLYDLGVVPTKEPFQKLFNQGMILGTSYRDHRGALVATDKVEKRDGSFFHVET  600
            YARFWHK LYDLGVVPTKEPFQKLFNQGMILGTSYRD RGALVATDKVEKRDGSFFHVET
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660
            GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  661  LDRVYRLITSKEIVAENNGGLDKVYNETVKSVTEQIELMKFNTAIAQLMVFVNAANKEDK  720
            LDRVYRLIT+KEI  EN+G+LDKVYNETVK+VTEQ++ MKFNTAIAQLMVFVNAANKEDK
Sbjct  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  721  LYVDYAKGFVQLIAPFAPHLAEELWQTLTATGESISYVAWPTWDESKLVEDEIEIVVQIK  780
            L+ DYAKGFVQLIAPFAPHL+EELWQ+LTA+GESISYV+WP+ DESKLVE+++EIVVQIK
Sbjct  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK  780

Query  781  GKVRAKLMVAKDLSREELQEVALADEKVKAEIDGKEIVKVIAVPNKLVNIVVK  833
            GKV+AKL+VAKDLSREELQEVALA+EKV+AEI GK+I+KVIAVPNKLVNIV+K
Sbjct  781  GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

37) leuS in NC_008532


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1254 bits (4757),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 754/833 (91%), Positives = 810/833 (98%), Gaps = 0/833 (0%)

Query  1    MSFYNHKEIEPKWQKYWADHHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60
            M+FY+H  IEPKWQ +WAD+HTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   ILSRFKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPADFTAENIANFKRQINALGFSYD  120
            ILSRFKRAQG NVLHPMGWDAFGLPAEQYAMDTGNDPA+FTAENIANFKRQINALGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WDREINTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180
            WDRE+NTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  181  GYPVVRKPMRQWMLKITAYAERLLNDLDELDWPESIKDMQRNWIGKSTGANVTFKVKGTD  240
            GYPVVRKPMRQWMLKITAYAERLL+DL+E+DWPESIKDMQRNWIGKSTGANVTFKVK+TD
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  241  KEFTVFTTRPDTLFGATFTVLAPEHDLVDAITSPEQAEAVANYKHQASLKSDLARTDLAK  300
            K+FTVFTTRPDTLFGAT++VLAPEH LVDAIT+++QAEAVA+YK+QASLKSDLARTDLAK
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  301  EKTGVWTGAYAINPVNGREIPIWIADYVLASYGTGAVMAVPAHDERDWEFAKQFGLPIVE  360
            EKTGVWTG+YAINPVNG+E+P+WIADYVLASYGTGA+MAVPAHDERDWEFAKQF L I+ 
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  361  VLEGGNVEEAAYTEDGPHVNSDFLNGLNKEEAIAKIVAWLEEKGFGQEKITYRLRDWLFS  420
            VLEGGNVEEAA+TEDG H+NSDFL+GL+K  AIAK+V WLE  G G+E++TYRLRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANLTDWLEVTRED  480
            RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLAN+TDWLEVTRED
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEDLLKQWLPVDIYVGGAEHAVLHLL  540
            GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADE+LLKQWLPVDIYVGGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  541  YARFWHKFLYDLGVVPTKEPFQKLFNQGMILGTSYRDHRGALVATDKVEKRDGSFFHVET  600
            YARFWHK LYDLGVVPTKEPFQKLFNQGMILGTSYRD RGALVATDKVEKRDGSFFHVET
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660
            GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  661  LDRVYRLITSKEIVAENNGGLDKVYNETVKSVTEQIELMKFNTAIAQLMVFVNAANKEDK  720
            LDRVYRLIT+KEI  EN+G+LDKVYNETVK+VTEQ++ MKFNTAIAQLMVFVNAANKEDK
Sbjct  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  721  LYVDYAKGFVQLIAPFAPHLAEELWQTLTATGESISYVAWPTWDESKLVEDEIEIVVQIK  780
            L+ DYAKGFVQLIAPFAPHL+EELWQ+LTA+GESISYV+WP+ DESKLVE+++EIVVQIK
Sbjct  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK  780

Query  781  GKVRAKLMVAKDLSREELQEVALADEKVKAEIDGKEIVKVIAVPNKLVNIVVK  833
            GKV+AKL+VAKDLSREELQEVALA+EKV+AEI GK+I+KVIAVPNKLVNIV+K
Sbjct  781  GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

38) leuS in NC_006448


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1254 bits (4757),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 754/833 (91%), Positives = 810/833 (98%), Gaps = 0/833 (0%)

Query  1    MSFYNHKEIEPKWQKYWADHHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60
            M+FY+H  IEPKWQ +WAD+HTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   ILSRFKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPADFTAENIANFKRQINALGFSYD  120
            ILSRFKRAQG NVLHPMGWDAFGLPAEQYAMDTGNDPA+FTAENIANFKRQINALGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WDREINTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180
            WDRE+NTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  181  GYPVVRKPMRQWMLKITAYAERLLNDLDELDWPESIKDMQRNWIGKSTGANVTFKVKGTD  240
            GYPVVRKPMRQWMLKITAYAERLL+DL+E+DWPESIKDMQRNWIGKSTGANVTFKVK+TD
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  241  KEFTVFTTRPDTLFGATFTVLAPEHDLVDAITSPEQAEAVANYKHQASLKSDLARTDLAK  300
            K+FTVFTTRPDTLFGAT++VLAPEH LVDAIT+++QAEAVA+YK+QASLKSDLARTDLAK
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  301  EKTGVWTGAYAINPVNGREIPIWIADYVLASYGTGAVMAVPAHDERDWEFAKQFGLPIVE  360
            EKTGVWTG+YAINPVNG+E+P+WIADYVLASYGTGA+MAVPAHDERDWEFAKQF L I+ 
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  361  VLEGGNVEEAAYTEDGPHVNSDFLNGLNKEEAIAKIVAWLEEKGFGQEKITYRLRDWLFS  420
            VLEGGNVEEAA+TEDG H+NSDFL+GL+K  AIAK+V WLE  G G+E++TYRLRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANLTDWLEVTRED  480
            RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLAN+TDWLEVTRED
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEDLLKQWLPVDIYVGGAEHAVLHLL  540
            GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADE+LLKQWLPVDIYVGGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  541  YARFWHKFLYDLGVVPTKEPFQKLFNQGMILGTSYRDHRGALVATDKVEKRDGSFFHVET  600
            YARFWHK LYDLGVVPTKEPFQKLFNQGMILGTSYRD RGALVATDKVEKRDGSFFHVET
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660
            GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  661  LDRVYRLITSKEIVAENNGGLDKVYNETVKSVTEQIELMKFNTAIAQLMVFVNAANKEDK  720
            LDRVYRLIT+KEI  EN+G+LDKVYNETVK+VTEQ++ MKFNTAIAQLMVFVNAANKEDK
Sbjct  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  721  LYVDYAKGFVQLIAPFAPHLAEELWQTLTATGESISYVAWPTWDESKLVEDEIEIVVQIK  780
            L+ DYAKGFVQLIAPFAPHL+EELWQ+LTA+GESISYV+WP+ DESKLVE+++EIVVQIK
Sbjct  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK  780

Query  781  GKVRAKLMVAKDLSREELQEVALADEKVKAEIDGKEIVKVIAVPNKLVNIVVK  833
            GKV+AKL+VAKDLSREELQEVALA+EKV+AEI GK+I+KVIAVPNKLVNIV+K
Sbjct  781  GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

39) Y1U_C0211 in NC_017927


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1254 bits (4757),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 754/833 (91%), Positives = 810/833 (98%), Gaps = 0/833 (0%)

Query  1    MSFYNHKEIEPKWQKYWADHHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60
            M+FY+H  IEPKWQ +WAD+HTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   ILSRFKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPADFTAENIANFKRQINALGFSYD  120
            ILSRFKRAQG NVLHPMGWDAFGLPAEQYAMDTGNDPA+FTAENIANFKRQINALGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WDREINTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180
            WDRE+NTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  181  GYPVVRKPMRQWMLKITAYAERLLNDLDELDWPESIKDMQRNWIGKSTGANVTFKVKGTD  240
            GYPVVRKPMRQWMLKITAYAERLL+DL+E+DWPESIKDMQRNWIGKSTGANVTFKVK+TD
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  241  KEFTVFTTRPDTLFGATFTVLAPEHDLVDAITSPEQAEAVANYKHQASLKSDLARTDLAK  300
            K+FTVFTTRPDTLFGAT++VLAPEH LVDAIT+++QAEAVA+YK+QASLKSDLARTDLAK
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  301  EKTGVWTGAYAINPVNGREIPIWIADYVLASYGTGAVMAVPAHDERDWEFAKQFGLPIVE  360
            EKTGVWTG+YAINPVNG+E+P+WIADYVLASYGTGA+MAVPAHDERDWEFAKQF L I+ 
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  361  VLEGGNVEEAAYTEDGPHVNSDFLNGLNKEEAIAKIVAWLEEKGFGQEKITYRLRDWLFS  420
            VLEGGNVEEAA+TEDG H+NSDFL+GL+K  AIAK+V WLE  G G+E++TYRLRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANLTDWLEVTRED  480
            RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLAN+TDWLEVTRED
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEDLLKQWLPVDIYVGGAEHAVLHLL  540
            GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADE+LLKQWLPVDIYVGGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  541  YARFWHKFLYDLGVVPTKEPFQKLFNQGMILGTSYRDHRGALVATDKVEKRDGSFFHVET  600
            YARFWHK LYDLGVVPTKEPFQKLFNQGMILGTSYRD RGALVATDKVEKRDGSFFHVET
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660
            GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  661  LDRVYRLITSKEIVAENNGGLDKVYNETVKSVTEQIELMKFNTAIAQLMVFVNAANKEDK  720
            LDRVYRLIT+KEI  EN+G+LDKVYNETVK+VTEQ++ MKFNTAIAQLMVFVNAANKEDK
Sbjct  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  721  LYVDYAKGFVQLIAPFAPHLAEELWQTLTATGESISYVAWPTWDESKLVEDEIEIVVQIK  780
            L+ DYAKGFVQLIAPFAPHL+EELWQ+LTA+GESISYV+WP+ DESKLVE+++EIVVQIK
Sbjct  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK  780

Query  781  GKVRAKLMVAKDLSREELQEVALADEKVKAEIDGKEIVKVIAVPNKLVNIVVK  833
            GKV+AKL+VAKDLSREELQEVALA+EKV+AEI GK+I+KVIAVPNKLVNIV+K
Sbjct  781  GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

40) STND_0220 in NC_017563


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1254 bits (4757),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 754/833 (91%), Positives = 810/833 (98%), Gaps = 0/833 (0%)

Query  1    MSFYNHKEIEPKWQKYWADHHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60
            M+FY+H  IEPKWQ +WAD+HTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   ILSRFKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPADFTAENIANFKRQINALGFSYD  120
            ILSRFKRAQG NVLHPMGWDAFGLPAEQYAMDTGNDPA+FTAENIANFKRQINALGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WDREINTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180
            WDRE+NTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  181  GYPVVRKPMRQWMLKITAYAERLLNDLDELDWPESIKDMQRNWIGKSTGANVTFKVKGTD  240
            GYPVVRKPMRQWMLKITAYAERLL+DL+E+DWPESIKDMQRNWIGKSTGANVTFKVK+TD
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  241  KEFTVFTTRPDTLFGATFTVLAPEHDLVDAITSPEQAEAVANYKHQASLKSDLARTDLAK  300
            K+FTVFTTRPDTLFGAT++VLAPEH LVDAIT+++QAEAVA+YK+QASLKSDLARTDLAK
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  301  EKTGVWTGAYAINPVNGREIPIWIADYVLASYGTGAVMAVPAHDERDWEFAKQFGLPIVE  360
            EKTGVWTG+YAINPVNG+E+P+WIADYVLASYGTGA+MAVPAHDERDWEFAKQF L I+ 
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  361  VLEGGNVEEAAYTEDGPHVNSDFLNGLNKEEAIAKIVAWLEEKGFGQEKITYRLRDWLFS  420
            VLEGGNVEEAA+TEDG H+NSDFL+GL+K  AIAK+V WLE  G G+E++TYRLRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANLTDWLEVTRED  480
            RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLAN+TDWLEVTRED
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEDLLKQWLPVDIYVGGAEHAVLHLL  540
            GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADE+LLKQWLPVDIYVGGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  541  YARFWHKFLYDLGVVPTKEPFQKLFNQGMILGTSYRDHRGALVATDKVEKRDGSFFHVET  600
            YARFWHK LYDLGVVPTKEPFQKLFNQGMILGTSYRD RGALVATDKVEKRDGSFFHVET
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660
            GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  661  LDRVYRLITSKEIVAENNGGLDKVYNETVKSVTEQIELMKFNTAIAQLMVFVNAANKEDK  720
            LDRVYRLIT+KEI  EN+G+LDKVYNETVK+VTEQ++ MKFNTAIAQLMVFVNAANKEDK
Sbjct  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  721  LYVDYAKGFVQLIAPFAPHLAEELWQTLTATGESISYVAWPTWDESKLVEDEIEIVVQIK  780
            L+ DYAKGFVQLIAPFAPHL+EELWQ+LTA+GESISYV+WP+ DESKLVE+++EIVVQIK
Sbjct  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK  780

Query  781  GKVRAKLMVAKDLSREELQEVALADEKVKAEIDGKEIVKVIAVPNKLVNIVVK  833
            GKV+AKL+VAKDLSREELQEVALA+EKV+AEI GK+I+KVIAVPNKLVNIV+K
Sbjct  781  GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

41) leuS in NC_011072


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1254 bits (4756),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 749/833 (90%), Positives = 809/833 (98%), Gaps = 0/833 (0%)

Query  1    MSFYNHKEIEPKWQGYWAEHHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60
            M+FY+H  IEPKWQ++WA++HTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   ILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120
            ILSR+KRAQG NVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180
            WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  181  GYPVVRKPMRQWMLKITAYAERLLNDLDELDWPESIKDMQRNWIGKSTGANVTFKVKGTD  240
            GYPVVRKPMRQWMLKITAYAERLL+DL+E+DWPESIKDMQRNWIGKSTGANVTFKVK+TD
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  241  KEFTVFTTRPDTLFGATFTVLAPEHELVDAITSSEQAEAVANYKHQASLKSDLARTDLAK  300
            K+FTVFTTRPDTLFGAT++VLAPEH LVDAIT+S+QAEAVA+YK+QASLKSDLARTDLAK
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  301  EKTGVWTGAYAINPVNGKEIPIWIADYVLASYGTGAVMAVPAHDQRDWEFAKQFDLPIVE  360
            EKTGVWTG+YAINPVNGKE+P+WIADYVLASYGTGA+MAVPAHD+RDWEFAKQF+L I+ 
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  361  VLEGGNVAEAAYTEDGLHVNSDFLDGLNKEEAIAKIVAWLEEKGCGQEKVTYRLRDWLFS  420
            VLEGGNV EAA+TEDGLH+NSDFLDGL+K  AIAK+V WLE  G G+E+VTYRLRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANLTDWLEVTRAD  480
            RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLAN+TDWLEVTR D
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEDLLKQWLPVDIYVGGAEHAVLHLL  540
            GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADE+LLKQWLPVDIYVGGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  541  YARFWHKFLYDLGVVPTKEPFQKLFNQGMILGTSYRDHRGALVTTDKVEKRDGSFFHVET  600
            YARFWHK LYDLGVVPTKEPFQKLFNQGMILGTSYRD RGALV+TDKVEKRDGSFFHVET
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660
            GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  661  LDRVYRLITSKEILAENNGALDKAYNETVKAVTEQIESLKFNTAIAQLMVFVNAANKEDK  720
            LDRVYRLIT+KEI  EN+GALDK YNETVKAVTEQ++ +KFNTAIAQLMVFVNAANKEDK
Sbjct  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  721  LYVDYAKGFIQLIAPFAPHLAEELWQTVAETGESISYVAWPTWDESKLVEDEIEIVVQIK  780
            L+ DYAKGF+QLIAPFAPHL+EELWQ+++ +GESISYV+WP+ DESKLVE+++EIVVQIK
Sbjct  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK  780

Query  781  GKVRAKLMVAKDLSREELQEIALADEKVKAEIDGKEIVKVISVPNKLVNIVVK  833
            GKV+AKL+VAKDLSREELQE+ALA+EKV+AEI GK+I+KVI+VPNKLVNIV+K
Sbjct  781  GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

42) leuS in NC_015875


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1254 bits (4757),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 749/833 (90%), Positives = 812/833 (98%), Gaps = 0/833 (0%)

Query  1    MSFYNHKEIEPKWQGYWAEHHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60
            M+FY+H  IEPKWQ++WA++HTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   ILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120
            ILSR+KRAQG NVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180
            WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  181  GYPVVRKPMRQWMLKITAYAERLLNDLDELDWPESIKDMQRNWIGKSTGANVTFKVRGTD  240
            GYPVVRKPMRQWMLKITAYAERLL+DL+E+DWPESIKDMQRNWIGKSTGANVTFKV++TD
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  241  KEFTVFTTRPDTLFGATFTVLAPEHELVDAITSTEQAEAVADYKHQASLKSDLARTDLAK  300
            K+FTVFTTRPDTLFGAT++VLAPEH LVDAIT+++QAEAVADYK+QASLKSDLARTDLAK
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  301  EKTGVWTGAYAINPVNGKEIPIWIADYVLASYGTGAVMAVPAHDQRDWEFAKQFDLPIVE  360
            EKTGVWTG+YAINPVNGKE+P+WIADYVLASYGTGA+MAVPAHD+RDWEFAKQF+L I+ 
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  361  VLEGGNVKEAAYTEDGLHVNSDFLDGLNKEDAIAKIVAWLEEKDCGQEKVTYRLRDWLFS  420
            VLEGGNV EAA+TEDGLH+NSDFLDGL+K  AIAK+V WLE  + G+E+VTYRLRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  421  RQRYWGEPIPIIHWEDGTSTAVPETELPLVLPVTKDIRPSGTGESPLANLTDWLEVTRED  480
            RQRYWGEPIPIIHWEDGTSTAVPE+ELPLVLPVTKDIRPSGTGESPLAN+TDWLEVTRED
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEDLLKQWLPVDIYVGGAEHAVLHLL  540
            GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADE+LLKQWLPVDIYVGGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  541  YARFWHKFLYDLGVVPTKEPFQKLFNQGMILGTSYRDHRGALVATDKVEKRDGSFFHIET  600
            YARFWHK LYDLGVVPTKEPFQKLFNQGMILGTSYRD RGALVATDKVEKRDGSFFH+ET
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGGRKF  660
            GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEG+RKF
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  661  LDRVYRLITSKEIVAENNGALDKVYNETVKAVTEQIESLKFNTAIAQLMVFVNAANKEDK  720
            LDRVYRLIT+KEI  EN+GALDKVYNETVKAVTEQ++ +KFNTAIAQLMVFVNAANKEDK
Sbjct  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  721  LYVDYAKGFIQLIAPFAPHLAEELWQTVAATGESISYVAWPTWDESKLVEDEVEIVIQIK  780
            L+ DYAKGF+QLIAPFAPHL+EELWQ+++A+GESISYV+WP+ DESKLVE++VEIV+QIK
Sbjct  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK  780

Query  781  GKVRAKVMVAKDLSREELQEIALADEKVKAEIDGKDIVKVIAVPNKLVNIVVK  833
            GKV+AK++VAKDLSREELQE+ALA+EKV+AEI GKDI+KVIAVPNKLVNIV+K
Sbjct  781  GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

43) leuS in NC_021195


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1253 bits (4755),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 814/833 (98%), Positives = 828/833 (99%), Gaps = 0/833 (0%)

Query  1    MTFYNHKEIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60
            MTFY+H  IEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120
            ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180
            WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSIGANvtfkvkdtd  240
            GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKS GANVTFKVKDTD
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  241  kdftvfttRPDTLFGATYAVLAPEHALVDAITTADQAEAVAEYKRQASLKSDLARTDLAK  300
            KDFTVFTTRPDTLFGATYAVLAPEHALVDAITT+DQAEAVA+YKRQASLKSDLARTDLAK
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  301  EKTGVWTGAYAINPVNGKEIPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360
            EKTGVWTG+YAINPVNGKE+PVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKAAAIAKMVEWLEAEGVGNEKVTYRLRDWLFS  420
            VLEGGNVEEAAFTEDGLHINSDFLDGLDKA+AIAKMVEWLEAEGVGNE+VTYRLRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANLTDWLEVTRED  480
            RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLAN+TDWLEVTRED
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540
            GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600
            YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFKGPLDASIAWSEEGLEGSRKF  660
            GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMF GPLDASIAWSEEGLEGSRKF
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720
            LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK
Sbjct  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  721  LFSDYAKGFVQLIAPFAPHLGEELWQVLTASGQSISYVPWPSYDESKLVENEIEIVVQIk  780
            LFSDYAKGFVQLIAPFAPHLGEELWQ LTASG+SISYVPWPSYDESKLVEN++EIVVQIK
Sbjct  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK  780

Query  781  gkvkaklvvakDLSREELQDLALANEKVQAEIAGKDIIKVIAVPNKLVNIVVK  833
            GKVKAKLVVAKDLSREELQ++ALANEKVQAEIAGKDIIKVIAVPNKLVNIV+K
Sbjct  781  GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

44) leuS in NC_021175


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1252 bits (4750),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 745/833 (90%), Positives = 810/833 (98%), Gaps = 0/833 (0%)

Query  1    MATYNHKEIEPKWQKYWAEHHTFKTGTDKDKPNFYALDMFPYPSGAGLHVGHPEGYTATD  60
            M+ Y+H  IEPKWQ +WA++HTFKTGTD  KP+FYALDMFPYPSGAGLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   ILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPADFTAENIANFKRQINALGFSYD  120
            ILSR+KRAQG NVLHPMGWDAFGLPAEQYAMDTGNDPA+FTAENIANFKRQINALGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180
            WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  181  GYPVVRKPMRQWMLKITAYAERLLNDLEELDWPESIKDMQRNWIGKSTGANVTFKIKGTD  240
            GYPVVRKPMRQWMLKITAYAERLL+DLEE+DWPESIKDMQRNWIGKSTGANVTFK+K+TD
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITSAEQAQAVADYKHAASLKSDLARTDLAK  300
            KDFTVFTTRPDTLFGATYAVLAPEHALVDAIT+++QA+AVADYK+ ASLKSDLARTDLAK
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  301  EKTGVWTGAYAINPVNGKEIPIWIADYVLASYGTGAIMAVPAHDERDWEFAKQFDLEIIP  360
            EKTGVWTG+YAINPVNGKE+P+WIADYVLASYGTGAIMAVPAHDERDWEFAKQF+L+IIP
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  361  VLEGGNVAEAAYTEDGPHINSGFLDGLDKAAAIEKMVAWLEAEGVGNEKVTYRLRDWLFS  420
            VLEGGNV EAA+TEDG HINS+FLDGLDKA+AI KMV WLEAEGVGNE+VTYRLRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  421  RQRYWGEPIPIIHWEDGTSTAVPENELPLVLPVTKDIRPSGTGESPLANLTDWLEVTRED  480
            RQRYWGEPIPIIHWEDGTSTAVPE+ELPLVLPVTKDIRPSGTGESPLAN+TDWLEVTRED
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNNEKLADEELLKAWLPVDIYIGGAEHAVLHLL  540
            GVKGRRETNTMPQWAGSSWYYLRYIDPHN EKLADEELLK WLPVDIY+GGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  541  YARFWHKFLYDLGVVPTKEPFQKLFNQGMILGTSYRDHRGALVATDKVEKRDGSFFNIET  600
            YARFWHK LYDLGVVPTKEPFQKLFNQGMILGTSYRD RGALVATDKVEKRDGSFF++ET
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  601  GEELEQAPAKMSKSLKNVVNPDDVVKQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660
            GEELEQAPAKMSKSLKNVVNPDDVV QYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  661  LDRVYRLLNSKELVSENSGALDKVYHETVKAVTEQIEDLKFNTAIAQLMIFVNAANKEEK  720
            LDRVYRL+ +KE+  ENSGALDKVY+ETVKAVTEQ++++KFNTAIAQLM+FVNAANKE+K
Sbjct  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  721  LYVEYAKGFIQLLAPFAPHLAEELWQAVAQTDESISYVAWPTYDESKLVEAEVEIVVQIK  780
            L+ +YAKGF+QL+APFAPHL+EELWQA++ ++ESISYV+WP+YDESKLVE +VEIVVQIK
Sbjct  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK  780

Query  781  GKVRAKLVVAKNLSREELQEIALADEKIKSEIAGKEVVKVITVPNKLVNIVVK  833
            GKV+AKLVVAK+LSREELQE+ALA+EK+++EIAGK+++KVI+VPNKLVNIV+K
Sbjct  781  GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

45) leuS in NC_018630


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1251 bits (4747),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 751/833 (91%), Positives = 811/833 (98%), Gaps = 0/833 (0%)

Query  1    MSFYNHKEIEPKWQGYWAEHHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60
            M+FY+H  IEPKWQ++WA++HTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   ILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120
            ILSR+KRAQG NVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180
            WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  181  GYPVVRKPMRQWMLKITAYAERLLNDLDELDWSESIKDMQRNWIGKSTGANVTFKVKGTD  240
            GYPVVRKPMRQWMLKITAYAERLL+DL+E+DW+ESIKDMQRNWIGKSTGANVTFKVK+TD
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  241  KEFTVFTTRPDTLFGATFTVLAPEHELVDAITSTEQAEAVADYKHQASLKSDLARTDLAK  300
            K+FTVFTTRPDTLFGAT++VLAPEH LVDAIT+++QAEAVADYK+QASLKSDLARTDLAK
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  301  EKTGVWTGAYAINPVNGKEIPIWIADYVLASYGTGAVMAVPAHDQRDWEFAKQFDLPIVE  360
            EKTGVWTG+YAINPVNGKE+P+WIADYVLASYGTGA+MAVPAHD+RDWEFAKQF+L I+ 
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  361  VLEGGNVEEAAYTEDGLHVNSDFLDGLNKEDAIAKIVACLEEKGCGQEKVTYRLRDWLFS  420
            VLEGGNVEEAA+TEDGLH+NSDFLDGL+K  AIAK+V  LE  G G+E+VTYRLRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANLTDWLEVTRED  480
            RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLAN+TDWLEVTRED
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEDLLKQWLPVDIYVGGAEHAVLHLL  540
            GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADE+LLKQWLPVDIYVGGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  541  YARFWHKFLYDLGVVPTKEPFQKLFNQGMILGTSYRDHRGALVATDKVEKRDGSFFHVET  600
            YARFWHK LYDLGVVPTKEPFQKLFNQGMILGTSYRD RGALVATDKVEKRDGSFFHVET
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660
            GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  661  LDRVYRLITSKEIIAENNGALDKVYNETVKAVTEQIESLKFNTAIAQLMVFVNAANKEDK  720
            LDRVYRLIT+KEI  EN+GALDKVYNETVKAVTEQ++ +KFNTAIAQLMVFVNAANKEDK
Sbjct  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  721  LYVDYAKGFIQLIAPFAPHLAEELWQTVAATGESISYVAWPTWDESKLVEDEIEIVVQIK  780
            L+ DYAKGF+QLIAPFAPHL+EELWQ+++A+GESISYV+WP+ DESKLVE+++EIVVQIK
Sbjct  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK  780

Query  781  GKVRAKLMVAKDLSREELQEIALADEKVKVEIDGKEIVKVISVPNKLVNIVVK  833
            GKV+AKL+VAKDLSREELQE+ALA+EKV+ EI GK+I+KVI+VPNKLVNIV+K
Sbjct  781  GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

46) leuS in NC_012467


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1251 bits (4747),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 751/833 (91%), Positives = 811/833 (98%), Gaps = 0/833 (0%)

Query  1    MSFYNHKEIEPKWQGYWAEHHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60
            M+FY+H  IEPKWQ++WA++HTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   ILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120
            ILSR+KRAQG NVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180
            WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  181  GYPVVRKPMRQWMLKITAYAERLLNDLDELDWSESIKDMQRNWIGKSTGANVTFKVKGTD  240
            GYPVVRKPMRQWMLKITAYAERLL+DL+E+DW+ESIKDMQRNWIGKSTGANVTFKVK+TD
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  241  KEFTVFTTRPDTLFGATFTVLAPEHELVDAITSTEQAEAVADYKHQASLKSDLARTDLAK  300
            K+FTVFTTRPDTLFGAT++VLAPEH LVDAIT+++QAEAVADYK+QASLKSDLARTDLAK
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  301  EKTGVWTGAYAINPVNGKEIPIWIADYVLASYGTGAVMAVPAHDQRDWEFAKQFDLPIVE  360
            EKTGVWTG+YAINPVNGKE+P+WIADYVLASYGTGA+MAVPAHD+RDWEFAKQF+L I+ 
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  361  VLEGGNVEEAAYTEDGLHVNSDFLDGLNKEDAIAKIVACLEEKGCGQEKVTYRLRDWLFS  420
            VLEGGNVEEAA+TEDGLH+NSDFLDGL+K  AIAK+V  LE  G G+E+VTYRLRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANLTDWLEVTRED  480
            RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLAN+TDWLEVTRED
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEDLLKQWLPVDIYVGGAEHAVLHLL  540
            GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADE+LLKQWLPVDIYVGGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  541  YARFWHKFLYDLGVVPTKEPFQKLFNQGMILGTSYRDHRGALVATDKVEKRDGSFFHVET  600
            YARFWHK LYDLGVVPTKEPFQKLFNQGMILGTSYRD RGALVATDKVEKRDGSFFHVET
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660
            GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  661  LDRVYRLITSKEIIAENNGALDKVYNETVKAVTEQIESLKFNTAIAQLMVFVNAANKEDK  720
            LDRVYRLIT+KEI  EN+GALDKVYNETVKAVTEQ++ +KFNTAIAQLMVFVNAANKEDK
Sbjct  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  721  LYVDYAKGFIQLIAPFAPHLAEELWQTVAATGESISYVAWPTWDESKLVEDEIEIVVQIK  780
            L+ DYAKGF+QLIAPFAPHL+EELWQ+++A+GESISYV+WP+ DESKLVE+++EIVVQIK
Sbjct  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK  780

Query  781  GKVRAKLMVAKDLSREELQEIALADEKVKVEIDGKEIVKVISVPNKLVNIVVK  833
            GKV+AKL+VAKDLSREELQE+ALA+EKV+ EI GK+I+KVI+VPNKLVNIV+K
Sbjct  781  GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

47) leuS in NC_017581


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1251 bits (4744),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 750/833 (91%), Positives = 809/833 (98%), Gaps = 0/833 (0%)

Query  1    MSFYNHKEIEPKWQKYWADHHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60
            M+FY+H  IEPKWQ +WAD+HTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   ILSRFKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPADFTAENIANFKRQINALGFSYD  120
            ILSRFKRAQG NVLHPMGWDAFGLPAEQYAMDTGNDPA+FTAENIANFKRQINALGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WDREINTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180
            WDRE+NTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  181  GYPVVRKPMRQWMLKITAYAERLLNDLDELDWPESIKDMQRNWIGKSTGANVTFKVKGTD  240
            GYPVVRKPMRQWMLKITAYAERLL+DL+E+DWPESIKDMQRNWIGKSTGANVTFKVK+TD
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  241  KEFTVFTTRPDTLFGATFTVLAPEHDLVDAITSPEQAEAVANYKHQASLKSDLARTDLAK  300
            K+FTVFTTRPDTLFGAT++VLAPEH LVDAIT+++QAEAVA+YK+QASLKSDLARTDLAK
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  301  EKTGVWTGAYAINPVNGREIPIWIADYVLASYGTGAVMAVPAHDERDWEFAKQFGLPIVE  360
            EKTGVWTG+YAINPVNG+E+P+WIADYVLASYGTGA+MAVPAHDERDWEFAKQF L I+ 
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  361  VLEGGNVEEAAYTEDGPHVNSDFLNGLNKEEAIAKIVAWLEEKGFGQEKITYRLRDWLFS  420
            VLEGGNVEEAA+TEDG H+NSDFL+GL+K  AIAK+V WLE  G G+E++TYRLRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANLTDWLEVTRED  480
            RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLAN+TDWLEVTRED
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEDLLKQWLPVDIYVGGAEHAVLHLL  540
            GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADE+LLKQWLPVDIYVGGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  541  YARFWHKFLYDLGVVPTKEPFQKLFNQGMILGTSYRDHRGALVATDKVEKRDGSFLHVET  600
            YARFWHK LYDLGVVPTKEPFQKLFNQGMILGTSYRD RGALVATDKVEKRDGSF+HVET
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660
            GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  661  LDRVYRLITSKEIVAENNGALDKVYNETVKSVTEQIESMKFNTAIAQLMVFVNAANKEDK  720
            LDRVYRLIT+KEI  EN+GALDKVYNETVK+VTEQ++ MKFNTAIAQLMVFVNAANKEDK
Sbjct  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  721  LYVGYAKGFIQLIAPFAPHLAEELWQTVAETGESISYVAWPTWDESKLVEDEIEIVVQIK  780
            L+ +YAKGF+QLIAPFAPHL+EELWQ+++ +GESISYV+WP+ DESKLVE+++EIVVQIK
Sbjct  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK  780

Query  781  GKVRAKLMVAKDLSREELQEVALANEKVKAEIDGKEIVKVIAVPNKLVNIVVK  833
            GKV+AKL+VAKDLSREELQEVALANEKV+AEI GK+I+KVIAVPNKLVNIV+K
Sbjct  781  GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

48) leuS in NC_012468


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1250 bits (4742),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 752/833 (91%), Positives = 810/833 (98%), Gaps = 0/833 (0%)

Query  1    MSFYNHKEIEPKWQGYWAEHHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60
            M+FY+H  IEPKWQ++WA++HTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   ILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120
            ILSR+KRAQG NVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180
            WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  181  GYPVVRKPMRQWMLKITAYAERLLNDLDELDWSESIKDMQRNWIGKSTGANVTFKVKGTD  240
            GYPVVRKPMRQWMLKITAYAERLL+DL+E+DW+ESIKDMQRNWIGKSTGANVTFKVK+TD
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  241  KEFTVFTTRPDTLFGATFTVLAPEHELVDAITSTEQAEAVADYKHQASLKSDLARTDLAK  300
            K+FTVFTTRPDTLFGAT++VLAPEH LVDAIT+++QAEAVADYK+QASLKSDLARTDLAK
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  301  EKTGVWTGAYAINPVNGKEIPIWIADYVLASYGTGAVMAVPAHDQRDWEFAKQFDLPIVE  360
            EKTGVWTG+YAINPVNGKE+P+WIADYVLASYGTGA+MAVPAHD+RDWEFAKQF+L I+ 
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  361  VLEGGNVEEAAYTEDGLHVNSDFLDGLNKEDAIAKIVACLEEKGCGQEKVTYRLRDWLFS  420
            VLEGGNVEEAA+TEDGLH+NSDFLDGL+K  AIAK+V  LE  G G+E+VTYRLRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANLTDWLEVTRED  480
            RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLAN+TDWLEVTRED
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEDLLKQWLPVDIYVGGAEHAVLHLL  540
            GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADE+LLKQWLPVDIYVGGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  541  YARFWHKFLYDLGVVPTKEPFQKLFNQGMILGTSYRDHRGALVATDKVEKRDGSFFHVET  600
            YARFWHK LYDLGVVPTKEPFQKLFNQGMILGTSYRD RGALVATDKVEKRDGSFFHVET
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660
            GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  661  LDRVYRLIRSKEIVAENNGALDKVYNETVKAVTEQIDSLKFNTAIAQLMVFVNAANKEDK  720
            LDRVYRLI +KEI  EN+GALDKVYNETVKAVTEQ+D +KFNTAIAQLMVFVNAANKEDK
Sbjct  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  721  LYVDYAKGFIQLIAPFAPHLAEELWQTVAATGESISYVTWPTWDESKLVEDEIEIVVQIK  780
            L+ DYAKGF+QLIAPFAPHL+EELWQ+++A+GESISYV WP+ DESKLVE+++EIVVQIK
Sbjct  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK  780

Query  781  GKVRAKLMVAKDLSREELQEIALADEKVKAEIDGKEIVKVISVPNKLVNIVVK  833
            GKV+AKL+VAKDLSREELQE+ALA+EKV+AEI GK+I+KVI+VPNKLVNIV+K
Sbjct  781  GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

49) leuS in NC_014498


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1249 bits (4739),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 750/833 (91%), Positives = 809/833 (98%), Gaps = 0/833 (0%)

Query  1    MSFYNHKEIEPKWQGYWAEHHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60
            M+FY+H  IEPKWQ++WA++HTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   ILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120
            ILSR+KRAQG NVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180
            WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  181  GYPVVRKPMRQWMLKITAYAERLLNDLDELDWSESIKDMQRNWIGKSTGANVTFKVKGTD  240
            GYPVVRKPMRQWMLKITAYAERLL+DL+E+DW+ESIKDMQRNWIGKSTGANVTFKVK+TD
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  241  KEFTVFTTRPDTLFGATFTVLAPEHELVDAITSSEQAEAVADYKHQASLKSDLARTDLAK  300
            K+FTVFTTRPDTLFGAT++VLAPEH LVDAIT+S+QAEAVADYK+QASLKSDLARTDLAK
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  301  EKTGVWIGAYAINPVNGKEMPIWIADYVLASYGTGAVMAVPAHDQRDWEFAKQFDLPIVE  360
            EKTGVW G+YAINPVNGKEMP+WIADYVLASYGTGA+MAVPAHD+RDWEFAKQF+L I+ 
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  361  VLEGGNVEEAAYTEDGLHVNSDFLDGLNKEDAIAKIVAYLEEKGCGQEKVTYRLRDWLFS  420
            VLEGGNVEEAA+TEDGLH+NSDFLDGL+K  AIAK+V  LE  G G+E+VTYRLRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  421  RQRYWGEPIPIIHWEDGTSTAVPETELPLVLPVTKDIRPSGTGESPLANLTDWLEVTRED  480
            RQRYWGEPIPIIHWEDGTSTAVPE+ELPLVLPVTKDIRPSGTGESPLAN+TDWLEVTRED
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEDLLKQWLPVDIYVGGAEHAVLHLL  540
            GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADE+LLKQWLPVDIYVGGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  541  YARFWHKFLYDLGVVPTKEPFQKLFNQGMILGTSYRDHRGALVTTDKVEKRDGSFFHVET  600
            YARFWHK LYDLGVVPTKEPFQKLFNQGMILGTSYRD RGALV+TDKVEKRDGSFFHVET
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660
            GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  661  LDRVYRLITSKEILAENNGALDKAYNETVKAVTEQIESLKFNTAIAQLMVFVNAANKEDK  720
            LDRVYRLIT+KEI  EN+GALDK YNETVKAVTEQ++ +KFNTAIAQLMVFVNAANKEDK
Sbjct  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  721  LYIDYAKGFIQLIAPFAPHLAEELWQTVAETGESISYVAWPTWDESKLVEDEIEIVVQIK  780
            L+ DYAKGF+QLIAPFAPHL+EELWQ+++ +GESISYV+WP+ DESKLVE+++EIVVQIK
Sbjct  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK  780

Query  781  GKVRAKLMVAKDLSREELQEIALADEKVKAEIDGKEIVKVIAVPNKLVNIVVK  833
            GKV+AKL+VAKDLSREELQE+ALA+EKV+AEI GK+I+KVIAVPNKLVNIV+K
Sbjct  781  GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

50) MYY_0336 in NC_017769


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1249 bits (4740),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 750/833 (91%), Positives = 809/833 (98%), Gaps = 0/833 (0%)

Query  1    MSFYNHKEIEPKWQGYWAEHHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60
            M+FY+H  IEPKWQ++WA++HTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   ILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120
            ILSR+KRAQG NVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180
            WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  181  GYPVVRKPMRQWMLKITAYAERLLNDLDELDWSESIKDMQRNWIGKSTGANVTFKVKGTD  240
            GYPVVRKPMRQWMLKITAYAERLL+DL+E+DW+ESIKDMQRNWIGKSTGANVTFKVK+TD
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  241  KEFTVFTTRPDTLFGATFTVLAPEHELVDAITSSEQAEAVADYKHQASLKSDLVRTDLAK  300
            K+FTVFTTRPDTLFGAT++VLAPEH LVDAIT+S+QAEAVADYK+QASLKSDL RTDLAK
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  301  EKTGVWTGAYAINPVNGKEMPIWIADYVLASYGTGAVMAVPAHDQRDWEFAKQFDLPIVE  360
            EKTGVWTG+YAINPVNGKEMP+WIADYVLASYGTGA+MAVPAHD+RDWEFAKQF+L I+ 
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  361  VLEGGNVEEAAYTEDGLHVNSDFLDGLNKEDAIAKIVAYLEEKGCGQEKVTYRLRDWLFS  420
            VLEGGNVEEAA+TEDGLH+NSDFLDGL+K  AIAK+V  LE  G G+E+VTYRLRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  421  RQRYWGEPIPIIHWEDGTSTAVPETELPLVLPVTKDIRPSGTGESPLANLTDWLEVTRED  480
            RQRYWGEPIPIIHWEDGTSTAVPE+ELPLVLPVTKDIRPSGTGESPLAN+TDWLEVTRED
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEDLLKQWLPVDIYVGGAEHAVLHLL  540
            GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADE+LLKQWLPVDIYVGGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  541  YARFWHKFLYDLGVVPTKEPFQKLFNQGMILGTSYRDHRGALVTTDKVEKRDGSFFHVET  600
            YARFWHK LYDLGVVPTKEPFQKLFNQGMILGTSYRD RGALV+TDKVEKRDGSFFHVET
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660
            GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  661  LDRVYRLITSKEILAENNGALDKAYNETVKAVTEQIESLKFNTAIAQLMVFVNAANKEDK  720
            LDRVYRLIT+KEI  EN+GALDK YNETVKAVTEQ++ +KFNTAIAQLMVFVNAANKEDK
Sbjct  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  721  LYIDYAKGFIQLIAPFAPHLAEELWQTVAETGESISYVAWPTWDESKLVEDEIEIVVQIK  780
            L+ DYAKGF+QLIAPFAPHL+EELWQ+++ +GESISYV+WP+ DESKLVE+++EIVVQIK
Sbjct  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK  780

Query  781  GKVRAKLMVAKDLSREELQEIALADEKVKAEIDGKEIVKVIAVPNKLVNIVVK  833
            GKV+AKL+VAKDLSREELQE+ALA+EKV+AEI GK+I+KVIAVPNKLVNIV+K
Sbjct  781  GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

51) leuS in NC_014251


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1249 bits (4740),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 750/833 (91%), Positives = 809/833 (98%), Gaps = 0/833 (0%)

Query  1    MSFYNHKEIEPKWQGYWAEHHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60
            M+FY+H  IEPKWQ++WA++HTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   ILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120
            ILSR+KRAQG NVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180
            WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  181  GYPVVRKPMRQWMLKITAYAERLLNDLDELDWSESIKDMQRNWIGKSTGANVTFKVKGTD  240
            GYPVVRKPMRQWMLKITAYAERLL+DL+E+DW+ESIKDMQRNWIGKSTGANVTFKVK+TD
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  241  KEFTVFTTRPDTLFGATFTVLAPEHELVDAITSSEQAEAVADYKHQASLKSDLVRTDLAK  300
            K+FTVFTTRPDTLFGAT++VLAPEH LVDAIT+S+QAEAVADYK+QASLKSDL RTDLAK
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  301  EKTGVWTGAYAINPVNGKEMPIWIADYVLASYGTGAVMAVPAHDQRDWEFAKQFDLPIVE  360
            EKTGVWTG+YAINPVNGKEMP+WIADYVLASYGTGA+MAVPAHD+RDWEFAKQF+L I+ 
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  361  VLEGGNVEEAAYTEDGLHVNSDFLDGLNKEDAIAKIVAYLEEKGCGQEKVTYRLRDWLFS  420
            VLEGGNVEEAA+TEDGLH+NSDFLDGL+K  AIAK+V  LE  G G+E+VTYRLRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  421  RQRYWGEPIPIIHWEDGTSTAVPETELPLVLPVTKDIRPSGTGESPLANLTDWLEVTRED  480
            RQRYWGEPIPIIHWEDGTSTAVPE+ELPLVLPVTKDIRPSGTGESPLAN+TDWLEVTRED
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEDLLKQWLPVDIYVGGAEHAVLHLL  540
            GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADE+LLKQWLPVDIYVGGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  541  YARFWHKFLYDLGVVPTKEPFQKLFNQGMILGTSYRDHRGALVTTDKVEKRDGSFFHVET  600
            YARFWHK LYDLGVVPTKEPFQKLFNQGMILGTSYRD RGALV+TDKVEKRDGSFFHVET
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660
            GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  661  LDRVYRLITSKEILAENNGALDKAYNETVKAVTEQIESLKFNTAIAQLMVFVNAANKEDK  720
            LDRVYRLIT+KEI  EN+GALDK YNETVKAVTEQ++ +KFNTAIAQLMVFVNAANKEDK
Sbjct  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  721  LYIDYAKGFIQLIAPFAPHLAEELWQTVAETGESISYVAWPTWDESKLVEDEIEIVVQIK  780
            L+ DYAKGF+QLIAPFAPHL+EELWQ+++ +GESISYV+WP+ DESKLVE+++EIVVQIK
Sbjct  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK  780

Query  781  GKVRAKLMVAKDLSREELQEIALADEKVKAEIDGKEIVKVIAVPNKLVNIVVK  833
            GKV+AKL+VAKDLSREELQE+ALA+EKV+AEI GK+I+KVIAVPNKLVNIV+K
Sbjct  781  GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

52) SPAP_0303 in NC_014494


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1249 bits (4738),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 749/833 (90%), Positives = 809/833 (98%), Gaps = 0/833 (0%)

Query  1    MSFYNHKEIEPKWQGYWAEHHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60
            M+FY+H  IEPKWQ++WA++HTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   ILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTSENIANFKRQINALGFSYD  120
            ILSR+KRAQG NVLHPMGWDAFGLPAEQYAMDTGNDPAEFT+ENIANFKRQINALGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180
            WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  181  GYPVVRKPMRQWMLKITAYAERLLNDLDELDWSESIKDMQRNWIGKSTGANVTFKVKGTD  240
            GYPVVRKPMRQWMLKITAYAERLL+DL+E+DW+ESIKDMQRNWIGKSTGANVTFKVK+TD
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  241  KEFTVFTTRPDTLFGATFTVLAPEHELVDAITSSEQAEAVVDYKHQASLKSDLARTDLAK  300
            K+FTVFTTRPDTLFGAT++VLAPEH LVDAIT+S+QAEAV DYK+QASLKSDLARTDLAK
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  301  EKTGVWTGAYAINPVNGKEMPIWIADYVLASYGTGAVMAVPAHDQRDWEFAKQFDLPIVE  360
            EKTGVWTG+YAINPVNGKEMP+WIADYVLASYGTGA+MAVPAHD+RDWEFAKQF+L I+ 
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  361  VLEGGNVEEAAYTEDGLHVNSDFLDGLNKEDAIAKIVACLEEKGCGQEKVTYRLRDWLFS  420
            VLEGGNVEEAA+TEDGLH+NSDFLDGL+K  AIAK+V  LE  G G+E+VTYRLRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  421  RQRYWGEPIPIIHWEDGTSTAVPETELPLVLPVTKDIRPSGTGESPLANLTDWLEVTRED  480
            RQRYWGEPIPIIHWEDGTSTAVPE+ELPLVLPVTKDIRPSGTGESPLAN+TDWLEVTRED
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEDLLKQWLPVDIYVGGAEHAVLHLL  540
            GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADE+LLKQWLPVDIYVGGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  541  YARFWHKFLYDLGVVPTKEPFQKLFNQGMILGTSYRDHRGALVATDKVEKRDGSFFHVET  600
            YARFWHK LYDLGVVPTKEPFQKLFNQGMILGTSYRD RGALVATDKVEKRDGSFFHVET
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660
            GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  661  LDRVYRLITSKEILAENNGALDKAYNETVKAVTEQIESLKFNTAIAQLMVFVNAANKEDK  720
            LDRVYRLIT+KEI  EN+GALDK YNETVKAVTEQ++ +KFNTAIAQLMVFVNAANKEDK
Sbjct  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  721  LYVDYAKGFIQLIAPFAPHLAEELWQTVAETGESISYVAWPTWDESKLVEDEIEIVVQIK  780
            L+ DYAKGF+QLIAPFAPHL+EELWQ+++ +GESISYV+WP+ DESKLVE+++EIVVQIK
Sbjct  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK  780

Query  781  GKVRAKLMVAKDLSREELQEIALADEKVKAEIDGKEIVKVISVPNKLVNIVVK  833
            GKV+AKL+VAKDLSREELQE+ALA+EKV+AEI GK+I+KVI+VPNKLVNIV+K
Sbjct  781  GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

53) leuS in NC_011900


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1249 bits (4737),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 749/833 (90%), Positives = 809/833 (98%), Gaps = 0/833 (0%)

Query  1    MSFYNHKEIEPKWQGYWAEHHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60
            M+FY+H  IEPKWQ++WA++HTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   ILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120
            ILSR+KRAQG NVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180
            WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  181  GYPVVRKPMRQWMLKITAYAERLLNDLDELDWSESIKDMQRNWIGKSTGANVTFKVKGTD  240
            GYPVVRKPMRQWMLKITAYAERLL+DL+E+DW+ESIKDMQRNWIGKSTGANVTFKVK+TD
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  241  KEFTVFTTRPDTLFGATFTVLAPEHELVDAITSSEQAEAVADYKHQASLKSDLVRTDLAK  300
            K+FTVFTTRPDTLFGAT++VLAPEH LVDAIT+S+QAEAVADYK+QASLKSDL RTDLAK
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  301  EKTGVWTGAYAINPVNGKEMPIWIADYVLASYGTGAVMAVPAHDQRDWEFAKQFDLPIVE  360
            EKTGVWTG+YAINPVNGKEMP+WIADYVLASYGTGA+MAVPAHD+RDWEFAKQF+L I+ 
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  361  VLEGGNVEEAAYTEDGLHVNSDFLDGLNKEDAIAKIVACLEEKGCGQEKVTYRLRDWLFS  420
            VLEGGNVEEAA+TEDGLH+NSDFLDGL+K  AIAK+V  LE  G G+E+VTYRLRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  421  RQRYWGEPIPIIHWEDGTSTAVPETELPLVLPVTKDIRPSGTGESPLANLTDWLEVTRED  480
            RQRYWGEPIPIIHWEDGTSTAVPE+ELPLVLPVTKDIRPSGTGESPLAN+TDWLEVTRED
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEDLLKQWLPVDIYVGGAEHAVLHLL  540
            GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADE+LLKQWLPVDIYVGGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  541  YARFWHKFLYDLGVVPTKEPFQKLFNQGMILGTSYRDHRGALVATDKVEKRDGSFFHIET  600
            YARFWHK LYDLGVVPTKEPFQKLFNQGMILGTSYRD RGALVATDKVEKRDGSFFH+ET
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660
            GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  661  LDRVYRLITSKEILAENNGALDKAYNETVKAVTEQIESLKFNTAIAQLMVFVNAANKEDK  720
            LDRVYRLIT+KEI  EN+GALDK YNETVKAVTEQ++ +KFNTAIAQLMVFVNAANKEDK
Sbjct  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  721  LYVDYAKGFIQLIAPFAPHLAEELWQTVAETGESISYVAWPTWDESKLVEDEIEIVVQIK  780
            L+ DYAKGF+QLIAPFAPHL+EELWQ+++ +GESISYV+WP+ DESKLVE+++EIVVQIK
Sbjct  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK  780

Query  781  GKVRAKLMVAKDLSREELQEIALADEKVKAEIDGKEIVKVISVPNKLVNIVVK  833
            GKV+AKL+VAKDLSREELQE+ALA+EKV+AEI GK+I+KVI+VPNKLVNIV+K
Sbjct  781  GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

54) leuS in NC_012466


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1249 bits (4737),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 749/833 (90%), Positives = 809/833 (98%), Gaps = 0/833 (0%)

Query  1    MSFYNHKEIEPKWQGYWAEHHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60
            M+FY+H  IEPKWQ++WA++HTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   ILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120
            ILSR+KRAQG NVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180
            WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  181  GYPVVRKPMRQWMLKITAYAERLLNDLDELDWSESIKDMQRNWIGKSTGANVTFKVKGTD  240
            GYPVVRKPMRQWMLKITAYAERLL+DL+E+DW+ESIKDMQRNWIGKSTGANVTFKVK+TD
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  241  KEFTVFTTRPDTLFGATFTVLAPEHELVDAITSSEQAEAVADYKHQASLKSDLVRTDLAK  300
            K+FTVFTTRPDTLFGAT++VLAPEH LVDAIT+S+QAEAVADYK+QASLKSDL RTDLAK
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  301  EKTGVWTGAYAINPVNGKEMPIWIADYVLASYGTGAVMAVPAHDQRDWEFAKQFDLPIVE  360
            EKTGVWTG+YAINPVNGKEMP+WIADYVLASYGTGA+MAVPAHD+RDWEFAKQF+L I+ 
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  361  VLEGGNVEEAAYTEDGLHVNSDFLDGLNKEDAIAKIVACLEEKGCGQEKVTYRLRDWLFS  420
            VLEGGNVEEAA+TEDGLH+NSDFLDGL+K  AIAK+V  LE  G G+E+VTYRLRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  421  RQRYWGEPIPIIHWEDGTSTAVPETELPLVLPVTKDIRPSGTGESPLANLTDWLEVTRED  480
            RQRYWGEPIPIIHWEDGTSTAVPE+ELPLVLPVTKDIRPSGTGESPLAN+TDWLEVTRED
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEDLLKQWLPVDIYVGGAEHAVLHLL  540
            GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADE+LLKQWLPVDIYVGGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  541  YARFWHKFLYDLGVVPTKEPFQKLFNQGMILGTSYRDHRGALVATDKVEKRDGSFFHIET  600
            YARFWHK LYDLGVVPTKEPFQKLFNQGMILGTSYRD RGALVATDKVEKRDGSFFH+ET
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660
            GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  661  LDRVYRLITSKEILAENNGALDKAYNETVKAVTEQIESLKFNTAIAQLMVFVNAANKEDK  720
            LDRVYRLIT+KEI  EN+GALDK YNETVKAVTEQ++ +KFNTAIAQLMVFVNAANKEDK
Sbjct  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  721  LYVDYAKGFIQLIAPFAPHLAEELWQTVAETGESISYVAWPTWDESKLVEDEIEIVVQIK  780
            L+ DYAKGF+QLIAPFAPHL+EELWQ+++ +GESISYV+WP+ DESKLVE+++EIVVQIK
Sbjct  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK  780

Query  781  GKVRAKLMVAKDLSREELQEIALADEKVKAEIDGKEIVKVISVPNKLVNIVVK  833
            GKV+AKL+VAKDLSREELQE+ALA+EKV+AEI GK+I+KVI+VPNKLVNIV+K
Sbjct  781  GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

55) leuS in NC_017592


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1249 bits (4737),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 749/833 (90%), Positives = 810/833 (98%), Gaps = 0/833 (0%)

Query  1    MSFYNHKEIEPKWQGYWAEHHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60
            M+FY+H  IEPKWQ++WA++HTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   ILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120
            ILSR+KRAQG NVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180
            WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  181  GYPVVRKPMRQWMLKITAYAERLLNDLDELDWSESIKDMQRNWIGKSTGANVTFKVKGTD  240
            GYPVVRKPMRQWMLKITAYAERLL+DL+E+DW+ESIKDMQRNWIGKSTGANVTFKVK+TD
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  241  KEFTVFTTRPDTLFGATFTVLAPEHELVDAITSSEQAEAVADYKHQASLKSDLARTDLAK  300
            K+FTVFTTRPDTLFGAT++VLAPEH LVDAIT+S+QAEAVADYK+QASLKSDLARTDLAK
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  301  EKTGVWTGAYAINPVNGKEMPIWIADYVLASYGTGAVMAVPAHDQRDWEFAKQFDLPIVE  360
            EKTGVWTG+YAINPVNGKEMP+WIADYVLASYGTGA+MAVPAHD+RDWEFAKQF+L I+ 
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  361  VLEGGNVEEAAYTEDGLHVNSDFLDGLNKEDAIAKIVACLEEKGCGQEKVTYRLRDWLFS  420
            VLEGGNVEEAA+TEDGLH+NSDFLDGL+K  AIAK+V  LE  G G+E+VTYRLRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  421  RQRYWGEPIPIIHWEDGTSTAVPETELPLVLPVTKDIRPSGTGESPLANLTDWLEVTRED  480
            RQRYWGEPIPIIHWEDGTSTAVPE+ELPLVLPVTKDIRPSGTGESPLAN+TDWLEVTRED
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEDLLKQWLPVDIYVGGAEHAVLHLL  540
            GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADE+LLKQWLPVDIYVGGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  541  YARFWHKFLYDLGVVPTKEPFQKLFNQGMILGTSYRDHRGALVATDKVEKRDGSFFHIET  600
            YARFWHK LYDLGVVPTKEPFQKLFNQGMILGTSYRD RGALVATDKVEKRDGSFFH+ET
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660
            GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  661  LDRVYRLITSKEILAENNGALDKAYNETVKAVTEQIESLKFNTAIAQLMVFVNAANKEDK  720
            LDRVYRLIT+KEI  EN+GALDK YNETVKAVTEQ++ +KFNTAIAQLMVFVNAANKEDK
Sbjct  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  721  LYVDYAKGFIQLIAPFAPHLAEELWQTVAETGESISYVAWPTWDESKLVEDEIEIVVQIK  780
            L+ DYAKGF+QLIAPFAPHL+EELWQ+++ +GESISYV+WP+ DESKLVE+++EIVVQIK
Sbjct  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK  780

Query  781  GKVRAKLMVAKDISREELQEIALADEKVKAEIDGKEIVKVISVPNKLVNIVVK  833
            GKV+AKL+VAKD+SREELQE+ALA+EKV+AEI GK+I+KVI+VPNKLVNIV+K
Sbjct  781  GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

56) leuS in NC_021006


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1249 bits (4737),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 749/833 (90%), Positives = 810/833 (98%), Gaps = 0/833 (0%)

Query  1    MSFYNHKEIEPKWQGYWAEHHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60
            M+FY+H  IEPKWQ++WA++HTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   ILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120
            ILSR+KRAQG NVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180
            WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  181  GYPVVRKPMRQWMLKITAYAERLLNDLDELDWSESIKDMQRNWIGKSTGANVTFKVKGTD  240
            GYPVVRKPMRQWMLKITAYAERLL+DL+E+DW+ESIKDMQRNWIGKSTGANVTFKVK+TD
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  241  KEFTVFTTRPDTLFGATFTVLAPEHELVDAITSSEQAEAVADYKHQASLKSDLARTDLAK  300
            K+FTVFTTRPDTLFGAT++VLAPEH LVDAIT+S+QAEAVADYK+QASLKSDLARTDLAK
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  301  EKTGVWTGAYAINPVNGKEMPIWIADYVLASYGTGAVMAVPAHDQRDWEFAKQFDLPIVE  360
            EKTGVWTG+YAINPVNGKEMP+WIADYVLASYGTGA+MAVPAHD+RDWEFAKQF+L I+ 
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  361  VLEGGNVEEAAYTEDGLHVNSDFLDGLNKEDAIAKIVACLEEKGCGQEKVTYRLRDWLFS  420
            VLEGGNVEEAA+TEDGLH+NSDFLDGL+K  AIAK+V  LE  G G+E+VTYRLRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  421  RQRYWGEPIPIIHWEDGTSTAVPETELPLVLPVTKDIRPSGTGESPLANLTDWLEVTRED  480
            RQRYWGEPIPIIHWEDGTSTAVPE+ELPLVLPVTKDIRPSGTGESPLAN+TDWLEVTRED
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEDLLKQWLPVDIYVGGAEHAVLHLL  540
            GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADE+LLKQWLPVDIYVGGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  541  YARFWHKFLYDLGVVPTKEPFQKLFNQGMILGTSYRDHRGALVATDKVEKRDGSFFHIET  600
            YARFWHK LYDLGVVPTKEPFQKLFNQGMILGTSYRD RGALVATDKVEKRDGSFFH+ET
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660
            GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  661  LDRVYRLITSKEILAENNGALDKAYNETVKAVTEQIESLKFNTAIAQLMVFVNAANKEDK  720
            LDRVYRLIT+KEI  EN+GALDK YNETVKAVTEQ++ +KFNTAIAQLMVFVNAANKEDK
Sbjct  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  721  LYVDYAKGFIQLIAPFAPHLAEELWQTVAETGESISYVAWPTWDESKLVEDEIEIVVQIK  780
            L+ DYAKGF+QLIAPFAPHL+EELWQ+++ +GESISYV+WP+ DESKLVE+++EIVVQIK
Sbjct  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK  780

Query  781  GKVRAKLMVAKDISREELQEIALADEKVKAEIDGKEIVKVISVPNKLVNIVVK  833
            GKV+AKL+VAKD+SREELQE+ALA+EKV+AEI GK+I+KVI+VPNKLVNIV+K
Sbjct  781  GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

57) leuS in NC_021028


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1249 bits (4737),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 749/833 (90%), Positives = 810/833 (98%), Gaps = 0/833 (0%)

Query  1    MSFYNHKEIEPKWQGYWAEHHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60
            M+FY+H  IEPKWQ++WA++HTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   ILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120
            ILSR+KRAQG NVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180
            WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  181  GYPVVRKPMRQWMLKITAYAERLLNDLDELDWSESIKDMQRNWIGKSTGANVTFKVKGTD  240
            GYPVVRKPMRQWMLKITAYAERLL+DL+E+DW+ESIKDMQRNWIGKSTGANVTFKVK+TD
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  241  KEFTVFTTRPDTLFGATFTVLAPEHELVDAITSSEQAEAVADYKHQASLKSDLARTDLAK  300
            K+FTVFTTRPDTLFGAT++VLAPEH LVDAIT+S+QAEAVADYK+QASLKSDLARTDLAK
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  301  EKTGVWTGAYAINPVNGKEMPIWIADYVLASYGTGAVMAVPAHDQRDWEFAKQFDLPIVE  360
            EKTGVWTG+YAINPVNGKEMP+WIADYVLASYGTGA+MAVPAHD+RDWEFAKQF+L I+ 
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  361  VLEGGNVEEAAYTEDGLHVNSDFLDGLNKEDAIAKIVACLEEKGCGQEKVTYRLRDWLFS  420
            VLEGGNVEEAA+TEDGLH+NSDFLDGL+K  AIAK+V  LE  G G+E+VTYRLRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  421  RQRYWGEPIPIIHWEDGTSTAVPETELPLVLPVTKDIRPSGTGESPLANLTDWLEVTRED  480
            RQRYWGEPIPIIHWEDGTSTAVPE+ELPLVLPVTKDIRPSGTGESPLAN+TDWLEVTRED
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEDLLKQWLPVDIYVGGAEHAVLHLL  540
            GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADE+LLKQWLPVDIYVGGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  541  YARFWHKFLYDLGVVPTKEPFQKLFNQGMILGTSYRDHRGALVATDKVEKRDGSFFHIET  600
            YARFWHK LYDLGVVPTKEPFQKLFNQGMILGTSYRD RGALVATDKVEKRDGSFFH+ET
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660
            GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  661  LDRVYRLITSKEILAENNGALDKAYNETVKAVTEQIESLKFNTAIAQLMVFVNAANKEDK  720
            LDRVYRLIT+KEI  EN+GALDK YNETVKAVTEQ++ +KFNTAIAQLMVFVNAANKEDK
Sbjct  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  721  LYVDYAKGFIQLIAPFAPHLAEELWQTVAETGESISYVAWPTWDESKLVEDEIEIVVQIK  780
            L+ DYAKGF+QLIAPFAPHL+EELWQ+++ +GESISYV+WP+ DESKLVE+++EIVVQIK
Sbjct  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK  780

Query  781  GKVRAKLMVAKDISREELQEIALADEKVKAEIDGKEIVKVISVPNKLVNIVVK  833
            GKV+AKL+VAKD+SREELQE+ALA+EKV+AEI GK+I+KVI+VPNKLVNIV+K
Sbjct  781  GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

58) leuS in NC_021026


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1249 bits (4737),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 749/833 (90%), Positives = 810/833 (98%), Gaps = 0/833 (0%)

Query  1    MSFYNHKEIEPKWQGYWAEHHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60
            M+FY+H  IEPKWQ++WA++HTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   ILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120
            ILSR+KRAQG NVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180
            WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  181  GYPVVRKPMRQWMLKITAYAERLLNDLDELDWSESIKDMQRNWIGKSTGANVTFKVKGTD  240
            GYPVVRKPMRQWMLKITAYAERLL+DL+E+DW+ESIKDMQRNWIGKSTGANVTFKVK+TD
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  241  KEFTVFTTRPDTLFGATFTVLAPEHELVDAITSSEQAEAVADYKHQASLKSDLARTDLAK  300
            K+FTVFTTRPDTLFGAT++VLAPEH LVDAIT+S+QAEAVADYK+QASLKSDLARTDLAK
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  301  EKTGVWTGAYAINPVNGKEMPIWIADYVLASYGTGAVMAVPAHDQRDWEFAKQFDLPIVE  360
            EKTGVWTG+YAINPVNGKEMP+WIADYVLASYGTGA+MAVPAHD+RDWEFAKQF+L I+ 
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  361  VLEGGNVEEAAYTEDGLHVNSDFLDGLNKEDAIAKIVACLEEKGCGQEKVTYRLRDWLFS  420
            VLEGGNVEEAA+TEDGLH+NSDFLDGL+K  AIAK+V  LE  G G+E+VTYRLRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  421  RQRYWGEPIPIIHWEDGTSTAVPETELPLVLPVTKDIRPSGTGESPLANLTDWLEVTRED  480
            RQRYWGEPIPIIHWEDGTSTAVPE+ELPLVLPVTKDIRPSGTGESPLAN+TDWLEVTRED
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEDLLKQWLPVDIYVGGAEHAVLHLL  540
            GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADE+LLKQWLPVDIYVGGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  541  YARFWHKFLYDLGVVPTKEPFQKLFNQGMILGTSYRDHRGALVATDKVEKRDGSFFHIET  600
            YARFWHK LYDLGVVPTKEPFQKLFNQGMILGTSYRD RGALVATDKVEKRDGSFFH+ET
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660
            GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  661  LDRVYRLITSKEILAENNGALDKAYNETVKAVTEQIESLKFNTAIAQLMVFVNAANKEDK  720
            LDRVYRLIT+KEI  EN+GALDK YNETVKAVTEQ++ +KFNTAIAQLMVFVNAANKEDK
Sbjct  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  721  LYVDYAKGFIQLIAPFAPHLAEELWQTVAETGESISYVAWPTWDESKLVEDEIEIVVQIK  780
            L+ DYAKGF+QLIAPFAPHL+EELWQ+++ +GESISYV+WP+ DESKLVE+++EIVVQIK
Sbjct  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK  780

Query  781  GKVRAKLMVAKDISREELQEIALADEKVKAEIDGKEIVKVISVPNKLVNIVVK  833
            GKV+AKL+VAKD+SREELQE+ALA+EKV+AEI GK+I+KVI+VPNKLVNIV+K
Sbjct  781  GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

59) leuS in NC_021005


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1249 bits (4737),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 749/833 (90%), Positives = 810/833 (98%), Gaps = 0/833 (0%)

Query  1    MSFYNHKEIEPKWQGYWAEHHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60
            M+FY+H  IEPKWQ++WA++HTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   ILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120
            ILSR+KRAQG NVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180
            WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  181  GYPVVRKPMRQWMLKITAYAERLLNDLDELDWSESIKDMQRNWIGKSTGANVTFKVKGTD  240
            GYPVVRKPMRQWMLKITAYAERLL+DL+E+DW+ESIKDMQRNWIGKSTGANVTFKVK+TD
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  241  KEFTVFTTRPDTLFGATFTVLAPEHELVDAITSSEQAEAVADYKHQASLKSDLARTDLAK  300
            K+FTVFTTRPDTLFGAT++VLAPEH LVDAIT+S+QAEAVADYK+QASLKSDLARTDLAK
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  301  EKTGVWTGAYAINPVNGKEMPIWIADYVLASYGTGAVMAVPAHDQRDWEFAKQFDLPIVE  360
            EKTGVWTG+YAINPVNGKEMP+WIADYVLASYGTGA+MAVPAHD+RDWEFAKQF+L I+ 
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  361  VLEGGNVEEAAYTEDGLHVNSDFLDGLNKEDAIAKIVACLEEKGCGQEKVTYRLRDWLFS  420
            VLEGGNVEEAA+TEDGLH+NSDFLDGL+K  AIAK+V  LE  G G+E+VTYRLRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  421  RQRYWGEPIPIIHWEDGTSTAVPETELPLVLPVTKDIRPSGTGESPLANLTDWLEVTRED  480
            RQRYWGEPIPIIHWEDGTSTAVPE+ELPLVLPVTKDIRPSGTGESPLAN+TDWLEVTRED
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEDLLKQWLPVDIYVGGAEHAVLHLL  540
            GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADE+LLKQWLPVDIYVGGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  541  YARFWHKFLYDLGVVPTKEPFQKLFNQGMILGTSYRDHRGALVATDKVEKRDGSFFHIET  600
            YARFWHK LYDLGVVPTKEPFQKLFNQGMILGTSYRD RGALVATDKVEKRDGSFFH+ET
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660
            GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  661  LDRVYRLITSKEILAENNGALDKAYNETVKAVTEQIESLKFNTAIAQLMVFVNAANKEDK  720
            LDRVYRLIT+KEI  EN+GALDK YNETVKAVTEQ++ +KFNTAIAQLMVFVNAANKEDK
Sbjct  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  721  LYVDYAKGFIQLIAPFAPHLAEELWQTVAETGESISYVAWPTWDESKLVEDEIEIVVQIK  780
            L+ DYAKGF+QLIAPFAPHL+EELWQ+++ +GESISYV+WP+ DESKLVE+++EIVVQIK
Sbjct  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK  780

Query  781  GKVRAKLMVAKDISREELQEIALADEKVKAEIDGKEIVKVISVPNKLVNIVVK  833
            GKV+AKL+VAKD+SREELQE+ALA+EKV+AEI GK+I+KVI+VPNKLVNIV+K
Sbjct  781  GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

60) leuS in NC_018594


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1249 bits (4738),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 748/833 (90%), Positives = 808/833 (97%), Gaps = 0/833 (0%)

Query  1    MSFYNHKEIEPKWQGYWAEHHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60
            M+FY+H  IEPKWQ++WA++HTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   ILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120
            ILSR+KRAQG NVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180
            WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  181  GYPVVRKPMRQWMLKITAYAERLLNDLDDLDWPESIKNMQRNWIGKSTGANVTFKVKGTD  240
            GYPVVRKPMRQWMLKITAYAERLL+DL+++DWPESIK+MQRNWIGKSTGANVTFKVK+TD
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  241  KEFTVFTTRPDTLFGATFTVLAPEHELVDAITSSEQAEAVADYKHQASLKSDLVRTDLAK  300
            K+FTVFTTRPDTLFGAT++VLAPEH LVDAIT+S+QAEAVADYK+QASLKSDL RTDLAK
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  301  EKTGVWTGAYAINPVNGKGMPIWIADYVLASYGTGAVMAVPAHDQRDWEFAKQFDLPIVE  360
            EKTGVWTG+YAINPVNGK MP+WIADYVLASYGTGA+MAVPAHD+RDWEFAKQF+L I+ 
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  361  VLEGGNVEEAAYTEDGLHVNSDFLDGLNKEDAIAKIVACLEEKGCGQEKVTYRLRDWLFS  420
            VLEGGNVEEAA+TEDGLH+NSDFLDGL+K  AIAK+V  LE  G G+E+VTYRLRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  421  RQRYWGEPIPIIHWEDGTSTAVPETELPLVLPVTKDIRPSGTGESPLANLTDWLEVTRED  480
            RQRYWGEPIPIIHWEDGTSTAVPE+ELPLVLPVTKDIRPSGTGESPLAN+TDWLEVTRED
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEDLLKQWLPVDIYVGGAEHAVLHLL  540
            GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADE+LLKQWLPVDIYVGGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  541  YARFWHKFLYDLGVVPTKEPFQKLFNQGMILGTSYRDHRGALVATDKVEKRDGSFFHIET  600
            YARFWHK LYDLGVVPTKEPFQKLFNQGMILGTSYRD RGALVATDKVEKRDGSFFH+ET
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660
            GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  661  LDRVYRLITSKEILAENNGALDKAYNETVKAVTEQIESLKFNTAIAQLMVFVNAANKEDK  720
            LDRVYRLIT+KEI  EN+GALDK YNETVKAVTEQ++ +KFNTAIAQLMVFVNAANKEDK
Sbjct  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  721  LYVDYAKGFIQLIAPFAPHLAEELWQTVAETGESISYVAWPTWDESKLVEDEIEIVVQIK  780
            L+ DYAKGF+QLIAPFAPHL+EELWQ+++ +GESISYV+WP+ DESKLVE+++EIVVQIK
Sbjct  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK  780

Query  781  GKVRAKLMVAKDLSREELQEIALADEKVKAEIDGKEIVKVIAVPNKLVNIVVK  833
            GKV+AKL+VAKDLSREELQE+ALA+EKV+AEI GK+I+KVIAVPNKLVNIV+K
Sbjct  781  GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

61) leuS in NC_012469


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1249 bits (4740),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 749/833 (90%), Positives = 809/833 (98%), Gaps = 0/833 (0%)

Query  1    MSFYNHKEIEPKWQGYWAEHHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60
            M+FY+H  IEPKWQ++WA++HTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   ILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120
            ILSR+KRAQG NVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180
            WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  181  GYPVVRKPMRQWMLKITAYAERLLNDLDELDWSESIKDMQRNWIGKSTGANVTFKVKGTD  240
            GYPVVRKPMRQWMLKITAYAERLL+DL+E+DW+ESIKDMQRNWIGKSTGANVTFKVK+TD
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  241  KEFTVFTTRPDTLFGATFTVLAPEHELVDAITSSEQAEAVADYKHQASLKSDLVRTDLAK  300
            K+FTVFTTRPDTLFGAT++VLAPEH LVDAIT+S+QAEAVADYK+QASLKSDL RTDLAK
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  301  EKTGVWTGAYAINPVNGKEMPIWIADYVLASYGTGAVMAVPAHDQRDWEFAKQFDLPIVE  360
            EKTGVWTG+YAINPVNGKEMP+WIADYVLASYGTGA+MAVPAHD+RDWEFAKQF+L I+ 
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  361  VLEGGNVEEAAYTEDGLHVNSDFLDGLNKEDAIAKIVAYLEEKGCGQEKVTYRLRDWLFS  420
            VLEGGNVEEAA+TEDGLH+NSDFLDGL+K  AIAK+V  LE  G G+E+VTYRLRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  421  RQRYWGEPIPIIHWEDGTSTAVPETELPLVLPVTKDIRPSGTGESPLANLTDWLEVTRED  480
            RQRYWGEPIPIIHWEDGTSTAVPE+ELPLVLPVTKDIRPSGTGESPLAN+TDWLEVTRED
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEDLLKQWLPVDIYVGGAEHAVLHLL  540
            GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADE+LLKQWLPVDIYVGGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  541  YARFWHKFLYDLGVVPTKEPFQKLFNQGMILGTSYRDHRGALVTTDKVEKRDGSFFHVET  600
            YARFWHK LYDLGVVPTKEPFQKLFNQGMILGTSYRD RGALV+TDKVEKRDGSFFHVET
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660
            GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  661  LDRVYRLITSKEILAENNGALDKAYNETVKAVTEQIESLKFNTAIAQLMVFVNAANKEDK  720
            LDRVYRLIT+KEI  EN+GALDK YNETVKAVTEQ++ +KFNTAIAQLMVFVNAANKEDK
Sbjct  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  721  LYIDYAKGFIQLIAPFAPHLAEELWQTVAETGESISYVAWPTWDESKLVEDEIEIVVQIK  780
            L+ DYAKGF+QLIAPFAPHL+EELWQ+++ +GESISYV+WP+ DESKLVE+++EIVVQIK
Sbjct  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK  780

Query  781  GKVRAKLMVAKDLSREELQEIALADEKVKAEIDGKEIVKVISVPNKLVNIVVK  833
            GKV+AKL+VAKDLSREELQE+ALA+EKV+AEI GK+I+KVI+VPNKLVNIV+K
Sbjct  781  GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

62) leuS in NC_008533


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1248 bits (4734),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 748/833 (90%), Positives = 808/833 (97%), Gaps = 0/833 (0%)

Query  1    MSFYNHKEIEPKWQGYWAEHHTFKTGTDASKPKFYALDMFPYPSGVGLHVGHPEGYTATD  60
            M+FY+H  IEPKWQ++WA++HTFKTGTDASKPKFYALDMFPYPSG GLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   ILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120
            ILSR+KRAQG NVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180
            WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  181  GYPVVRKPMRQWMLKITAYAERLLNDLDELDWSESIKDMQRNWIGKSTGANVTFKVKGTD  240
            GYPVVRKPMRQWMLKITAYAERLL+DL+E+DW+ESIKDMQRNWIGKSTGANVTFKVK+TD
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  241  KEFTVFTTRPDTLFGATFTVLAPEHELVDAITSSEQAEAVADYKHQASLKSDLVRTDLAK  300
            K+FTVFTTRPDTLFGAT++VLAPEH LVDAIT+S+QAEAVADYK+QASLKSDL RTDLAK
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  301  EKTGVWTGAYAINPVNGKEMPIWIADYVLASYGTGAVMAVPAHDQRDWEFAKQFDLPIVE  360
            EKTGVWTG+YAINPVNGKEMP+WIADYVLASYGTGA+MAVPAHD+RDWEFAKQF+L I+ 
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  361  VLEGGNVEEAAYTEDGLHVNSDFLDGLNKEDAIAKIVACLEEKGCGQEKVTYRLRDWLFS  420
            VLEGGNVEEAA+TEDGLH+NSDFLDGL+K  AIAK+V  LE  G G+E+VTYRLRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  421  RQRYWGEPIPIIHWEDGTSTAVPETELPLVLPVTKDIRPSGTGESPLANLTDWLEVTRED  480
            RQRYWGEPIPIIHWEDGTSTAVPE+ELPLVLPVTKDIRPSGTGESPLAN+TDWLEVTRED
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEDLLKQWLPVDIYVGGAEHAVLHLL  540
            GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADE+LLKQWLPVDIYVGGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  541  YARFWHKFLYDLGVVPTKEPFQKLFNQGMILGTSYRDHRGALVATDKVEKRDGSFFHIET  600
            YARFWHK LYDLGVVPTKEPFQKLFNQGMILGTSYRD RGALVATDKVEKRDGSFFH+ET
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660
            GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  661  LDRVYRLITSKEILAENNGALDKAYNETVKAVTEQIESLKFNTAIAQLMVFVNAANKEDK  720
            LDRVYRLIT+KEI  EN+GALDK YNETVKAVTEQ++ +KFNTAIAQLMVFVNAANKEDK
Sbjct  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  721  LYVDYAKGFIQLIAPFAPHLAEELWQTVAETGESISYVAWPTWDESKLVEDEIEIVVQIK  780
            L+ DYAKGF+QLIAPFAPHL+EELWQ+++ +GESISYV+WP+ DESKLVE+++EIVVQIK
Sbjct  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK  780

Query  781  GKVRAKLMVAKDLSREELQEIALADEKVKAEIDGKEIVKVISVPNKLVNIVVK  833
            GKV+AKL+VAKDLSREELQE+ALA+EKV+AEI GK+I+KVI+VPNKLVNIV+K
Sbjct  781  GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

63) leuS in NC_017593


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1248 bits (4733),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 748/833 (90%), Positives = 809/833 (98%), Gaps = 0/833 (0%)

Query  1    MSFYNHKEIEPKWQGYWAEHHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60
            M+FY+H  IEPKWQ++WA++HTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   ILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTSENIANFKRQINALGFSYD  120
            ILSR+KRAQG NVLHPMGWDAFGLPAEQYAMDTGNDPAEFT+ENIANFKRQINALGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180
            WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  181  GYPVVRKPMRQWMLKITAYAERLLNDLDELDWSESIKDMQRNWIGKSTGANVTFKVKGTD  240
            GYPVVRKPMRQWMLKITAYAERLL+DL+E+DW+ESIKDMQRNWIGKSTGANVTFKVK+TD
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  241  KEFTVFTTRPDTLFGATFTVLAPEHELVDAITSSEQAEAVVDYKHQASLKSDLARTDLAK  300
            K+FTVFTTRPDTLFGAT++VLAPEH LVDAIT+S+QAEAV DYK+QASLKSDLARTDLAK
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  301  EKTGVWTGAYAINPVNGKEMPIWIADYVLASYGTGAVMAVPAHDQRDWEFAKQFDLPIVE  360
            EKTGVWTG+YAINPVNGKEMP+WIADYVLASYGTGA+MAVPAHD+RDWEFAKQF+L I+ 
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  361  VLEGGNVEEAAYTEDGLHVNSDFLDGLNKEDAIAKIVACLEEKGCGQEKVTYRLRDWLFS  420
            VLEGGNVEEAA+TEDGLH+NSDFLDGL+K  AIAK+V  LE  G G+E+VTYRLRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  421  RQRYWGEPIPIIHWEDGTSTAVPETELPLVLPVTKDIRPSGTGESPLANLTDWLEVTRED  480
            RQRYWGEPIPIIHWEDGTSTAVPE+ELPLVLPVTKDIRPSGTGESPLAN+TDWLEVTRED
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEDLLKQWLPVDIYVGGAEHAVLHLL  540
            GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADE+LLKQWLPVDIYVGGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  541  YARFWHKFLYDLGVVPTKEPFQKLFNQGMILGTSYRDHRGALVATDKVEKRDGSFFHIET  600
            YARFWHK LYDLGVVPTKEPFQKLFNQGMILGTSYRD RGALVATDKVEKRDGSFFH+ET
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660
            GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  661  LDRVYRLITSKEILAENNGALDKAYNETVKAVTEQIESLKFNTAIAQLMVFVNAANKEDK  720
            LDRVYRLIT+KEI  EN+GALDK YNETVKAVTEQ++ +KFNTAIAQLMVFVNAANKEDK
Sbjct  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  721  LYVDYAKGFIQLIAPFAPHLAEELWQTVAETDESISYVAWPTWDESKLVEDEIEIVVQIK  780
            L+ DYAKGF+QLIAPFAPHL+EELWQ+++ ++ESISYV+WP+ DESKLVE+++EIVVQIK
Sbjct  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK  780

Query  781  GKVRAKLMVAKDLSREELQEIALADEKVKAEIDGKEIVKVIAVPNKLVNIVVK  833
            GKV+AKL+VAKDLSREELQE+ALA+EKV+AEI GK+I+KVIAVPNKLVNIV+K
Sbjct  781  GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

64) leuS in NC_003098


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1248 bits (4734),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 748/833 (90%), Positives = 808/833 (97%), Gaps = 0/833 (0%)

Query  1    MSFYNHKEIEPKWQGYWAEHHTFKTGTDASKPKFYALDMFPYPSGVGLHVGHPEGYTATD  60
            M+FY+H  IEPKWQ++WA++HTFKTGTDASKPKFYALDMFPYPSG GLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   ILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120
            ILSR+KRAQG NVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180
            WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  181  GYPVVRKPMRQWMLKITAYAERLLNDLDELDWSESIKDMQRNWIGKSTGANVTFKVKGTD  240
            GYPVVRKPMRQWMLKITAYAERLL+DL+E+DW+ESIKDMQRNWIGKSTGANVTFKVK+TD
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  241  KEFTVFTTRPDTLFGATFTVLAPEHELVDAITSSEQAEAVADYKHQASLKSDLVRTDLAK  300
            K+FTVFTTRPDTLFGAT++VLAPEH LVDAIT+S+QAEAVADYK+QASLKSDL RTDLAK
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  301  EKTGVWTGAYAINPVNGKEMPIWIADYVLASYGTGAVMAVPAHDQRDWEFAKQFDLPIVE  360
            EKTGVWTG+YAINPVNGKEMP+WIADYVLASYGTGA+MAVPAHD+RDWEFAKQF+L I+ 
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  361  VLEGGNVEEAAYTEDGLHVNSDFLDGLNKEDAIAKIVACLEEKGCGQEKVTYRLRDWLFS  420
            VLEGGNVEEAA+TEDGLH+NSDFLDGL+K  AIAK+V  LE  G G+E+VTYRLRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  421  RQRYWGEPIPIIHWEDGTSTAVPETELPLVLPVTKDIRPSGTGESPLANLTDWLEVTRED  480
            RQRYWGEPIPIIHWEDGTSTAVPE+ELPLVLPVTKDIRPSGTGESPLAN+TDWLEVTRED
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEDLLKQWLPVDIYVGGAEHAVLHLL  540
            GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADE+LLKQWLPVDIYVGGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  541  YARFWHKFLYDLGVVPTKEPFQKLFNQGMILGTSYRDHRGALVATDKVEKRDGSFFHIET  600
            YARFWHK LYDLGVVPTKEPFQKLFNQGMILGTSYRD RGALVATDKVEKRDGSFFH+ET
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660
            GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  661  LDRVYRLITSKEILAENNGALDKAYNETVKAVTEQIESLKFNTAIAQLMVFVNAANKEDK  720
            LDRVYRLIT+KEI  EN+GALDK YNETVKAVTEQ++ +KFNTAIAQLMVFVNAANKEDK
Sbjct  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  721  LYVDYAKGFIQLIAPFAPHLAEELWQTVAETGESISYVAWPTWDESKLVEDEIEIVVQIK  780
            L+ DYAKGF+QLIAPFAPHL+EELWQ+++ +GESISYV+WP+ DESKLVE+++EIVVQIK
Sbjct  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK  780

Query  781  GKVRAKLMVAKDLSREELQEIALADEKVKAEIDGKEIVKVISVPNKLVNIVVK  833
            GKV+AKL+VAKDLSREELQE+ALA+EKV+AEI GK+I+KVI+VPNKLVNIV+K
Sbjct  781  GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

65) L897_00975 in NC_021807


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1247 bits (4729),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 813/833 (98%), Positives = 826/833 (99%), Gaps = 0/833 (0%)

Query  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60
            MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120
            ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180
            WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANvtfkvkdtd  240
            GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  241  kdftvfttRPDTLFGATYAVLAPEHALVDAITTADQAEAVAEYKRQASLKSDLARTDLAK  300
            KDFTVFTTRPDTLFGATYAVLAPEHALVDAITT+DQAEAVA+YKRQASLKSDLARTDLAK
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  301  EKTGVWTGSYAINPVNGNEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360
            EKTGVWTGSYAINPVNG+EMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNEKVTYRLRDWLFS  420
            VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNE+VTYRLRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480
            RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540
            GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600
            YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660
            GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  661  LDRVYRLVTTKEIVAENSGALDKVYNETVKAVTEQIETMKFNTAIAQLMIFVNAANKEDK  720
            LDRVYRL+TTKEI  ENSGALDKVYNETVKAVTEQ++ MKFNTAIAQLM+FVNAANKEDK
Sbjct  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  721  LFSDYAKGFVQLIAPFAPHLGEELWQMITQSDESIAHVAWPTWDESKLVENDVEIVVQIk  780
            LFSDYAKGFVQLIAPFAPHLGEELWQ +T S+ESI+ V+WP+ DESKLVENDVEIVVQIK
Sbjct  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK  780

Query  781  gkvkaklvvakDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833
            GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK
Sbjct  781  GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

66) leuS in NC_010582


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1246 bits (4727),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 747/833 (90%), Positives = 808/833 (97%), Gaps = 0/833 (0%)

Query  1    MSFYNHKEIEPKWQGYWAEHHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60
            M+FY+H  IEPKWQ++WA++HTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   ILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTSENIANFKRQINALGFSYD  120
            ILSR+KRAQG NVLHPMGWDAFGLPAEQYAMDTGNDPAEFT+ENIANFKRQINALGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180
            WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  181  GYPVVRKPMRQWMLKITAYAERLLNDLDELDWSESIKDMQRNWIGKSTGANVTFKVKGTD  240
            GYPVVRKPMRQWMLKITAYAERLL+DL+E+DW+ESIKDMQRNWIGKSTGANVTFKVK+TD
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  241  KEFTVFTTRPDTLFGATFTVLAPEHELVDAITSSEQAEAVVDYKHQASLKSDLARTDLAK  300
            K+FTVFTTRPDTLFGAT++VLAPEH LVDAIT+S+QAEAV DYK+QASLKSDLARTDLAK
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  301  EKTGVWTGAYAINPVNGKEMPIWIADYVLASYGTGAVMAVPAHDQRDWEFAKQFDLPIVE  360
            EKTGVWTG+YAINPVNGKEMP+WIADYVLASYGTGA+MAVPAHD+RDWEFAKQF+L I+ 
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  361  VLEGGNVEEAAYTEDGLHVNSDFLDGLNKEDAIAKIVACLEEKGCGQEKVTYRLRDWLFS  420
            VLEGGNVEEAA+TEDGLH+NSDFLDGL+K  AIAK+V  LE  G G+E+VTYRLRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  421  RQRYWGEPIPIIHWEDGTSTAVPETELPLVLPVTKDIRPSGTGESPLANLTDWLEVTRED  480
            RQRYWGEPIPIIHWEDGTSTAVPE+ELPLVLPVTKDIRPSGTGESPLAN+TDWLEVTRED
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEDLLKQWLPVDIYVGGAEHAVLHLL  540
            GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADE+LLKQWLPVDIYVGGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  541  YARFWHKFLYDLGVVPTKEPFQKLFNQGMILGTSYRDHRGALVATDKVEKRDGSFFHIET  600
            YARFWHK LYDLGVVPTKEPFQKLFNQGMILGTSYRD RGALVATDKVEKRDGSFFH+ET
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660
            GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  661  LDRVYRLITSKEILAENNGALDKAYNETVKAVTEQIESLKFNTAIAQLMVFVNAANKEDK  720
            LDRVYRLIT+KEI  EN+GALDK YNETVKAVTEQ++ +KFNTAIAQLMVFVNAANKEDK
Sbjct  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  721  LYVDYAKGFIQLIAPFAPHLAEELWQTVAETDKSISYVAWPTWDESKLVEDEIEIVVQIK  780
            L+ DYAKGF+QLIAPFAPHL+EELWQ+++ ++ SISYV+WP+ DESKLVE+++EIVVQIK
Sbjct  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK  780

Query  781  GKVRAKLMVAKDLSREELQEIALADEKVKAEIDGKEIVKVIAVPNKLVNIVVK  833
            GKV+AKL+VAKDLSREELQE+ALA+EKV+AEI GK+I+KVIAVPNKLVNIV+K
Sbjct  781  GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

67) leuS in NC_017905


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1243 bits (4714),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 757/833 (91%), Positives = 809/833 (98%), Gaps = 0/833 (0%)

Query  1    MSFYNHKEIEPKWQKYWADHHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60
            M+FY+H  IEPKWQ +WAD+HTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   ILSRFKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120
            ILSRFKRAQG NVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180
            WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  181  GYPVVRKPMRQWMLKITAYAERlladlddldWPESIKDMQRNWIGKSTGANVTFKVKGTD  240
            GYPVVRKPMRQWMLKITAYAERLL DL+++DWPESIKDMQRNWIGKSTGANVTFKVK+TD
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  241  KEFTVFTTRPDTLFGATFTVLAPEHELVDAITTPEQAEAVADYKHQASLKSDLARTDLAK  300
            K+FTVFTTRPDTLFGAT++VLAPEH LVDAITT++QAEAVADYK+QASLKSDLARTDLAK
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  301  EKTGVWTGAYAINPVNGKEIPIWIADYVLASYGTGAVMAVPAHDERDWEFAKQFGLPIVE  360
            EKTGVWTG+YAINPVNGKE+P+WIADYVLASYGTGA+MAVPAHDERDWEFAKQF L I+ 
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  361  VLEGGNVEEAAYTEDGLHVNSDFLNGLNKEEAIAKIVAWLEEKGFGQEKVTYRLRDWLFS  420
            VLEGGNVEEAA+TEDGLH+NSDFL+GL+K  AIAK+V WLE  G G+E+VTYRLRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANLTDWLEVTRED  480
            RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLAN+TDWLEVTRED
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEDLLKQWLPVDIYVGGAEHAVLHLL  540
            GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADE+LLKQWLPVDIYVGGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  541  YARFWHKFLYDLGVVPTKEPFQKLFNQGMILGTSYRDHRGALVATDKVEKRDGSFFHVET  600
            YARFWHK LYDLGVVPTKEPFQKLFNQGMILGTSYRD RGALVATDKVEKRDGSFFHVET
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660
            GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  661  LDRVYRLITSKEIVAENNGALDKVYNETVKAVTEQIESMKFNTAIAQLMVFVNAANKEDK  720
            LDRVYRLIT+KEI  EN+GALDKVYNETVKAVTEQ++ MKFNTAIAQLMVFVNAANKEDK
Sbjct  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  721  LYVDYAKGFIQLIAPFAPHLAEELWQTVAATGESISYVAWPTWDESKLIEDEIEIVVQIK  780
            L+ DYAKGF+QLIAPFAPHL+EELWQ+++A+GESISYV+WP+ DESKL+E+++EIVVQIK
Sbjct  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK  780

Query  781  GKVRAKLMVAKDLSREELQEVALADEKVKAEIDGKEIVKVISVPNKLVNIVTK  833
            GKV+AKL+VAKDLSREELQEVALA+EKV+AEI GK+I+KVI+VPNKLVNIV K
Sbjct  781  GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

68) leuS in NC_017567


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1241 bits (4708),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 777/833 (94%), Positives = 808/833 (97%), Gaps = 0/833 (0%)

Query  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60
            MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   ILSRFKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120
            ILSRFKRAQG NVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WDREVNTTDPDYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180
            WDREVNTTDP+YYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKGSD  240
            GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVK++D
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDEITSPEQAEAVADYKRQASLKSDLARTDLAK  300
            KDFTVFTTRPDTLFGATYAVLAPEHALVD IT+++QAEAVADYKRQASLKSDLARTDLAK
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  301  EKTGVWTGSYAINPVNGKEVPIWIADYVLASYGTGAIMAVPAHDERDWEFAKQFDLEIIP  360
            EKTGVWTGSYAINPVNGKE+P+WIADYVLASYGTGAIMAVPAHDERDWEFAKQF+L+IIP
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  361  VLEGGNVAEAAYTEDGRHINSDFLDGLDKADAIAKMVAWLEDKEVGNEKVTYRLRDWLFS  420
            VLEGGNV EAA+TEDG HINSDFLDGLDKA AIAKMV WLE   VGNE+VTYRLRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  421  RQRYWGEPIPIIHWEDGTSTAVPENELPLVLPVTSDIRPSGTGESPLANLTDWLEVTRED  480
            RQRYWGEPIPIIHWEDGTSTAVPE+ELPLVLPVT DIRPSGTGESPLAN+TDWLEVTRED
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  481  GVKGRRETNTMPQWAGSSWYYLRYIDPKNDQALADPELLKQWLPVDIYVGGAEHAVLHLL  540
            GVKGRRETNTMPQWAGSSWYYLRYIDP N + LAD ELLKQWLPVDIYVGGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDHRGALVATDKVEKRDGSFFHIET  600
            YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRD RGALVATDKVEKRDGSFFH+ET
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660
            GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  661  LDRVYRLVTTREIVAENSGALDKVYNETVKAVTEQIETMKFNTAIAQLMIFVNAANKEDQ  720
            LDRVYRL+TT+EI  ENSGALDKVYNETVKAVTEQ++ MKFNTAIAQLM+FVNAANKED+
Sbjct  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  721  LFVDYAKGFVQLIAPFAPHLGEELWQMITQSDESIAHVAWPTWDESKLVENDVEIVVQIk  780
            LF DYAKGFVQLIAPFAPHLGEELWQ +T S+ESI+ V+WP+ DESKLVENDVEIVVQIK
Sbjct  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK  780

Query  781  gkvkaklvvakDLSREDLEAAALANEKVQAEIAGKDIVKVIAVPNKLVNIVVK  833
            GKVKAKLVVAKDLSRE+L+  ALANEKVQAEIAGKDI+KVIAVPNKLVNIV+K
Sbjct  781  GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

69) leuS in NC_012891


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1241 bits (4708),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 777/833 (94%), Positives = 808/833 (97%), Gaps = 0/833 (0%)

Query  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60
            MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   ILSRFKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120
            ILSRFKRAQG NVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WDREVNTTDPDYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180
            WDREVNTTDP+YYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKGSD  240
            GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVK++D
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDEITSPEQAEAVADYKRQASLKSDLARTDLAK  300
            KDFTVFTTRPDTLFGATYAVLAPEHALVD IT+++QAEAVADYKRQASLKSDLARTDLAK
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  301  EKTGVWTGSYAINPVNGKEVPIWIADYVLASYGTGAIMAVPAHDERDWEFAKQFDLEIIP  360
            EKTGVWTGSYAINPVNGKE+P+WIADYVLASYGTGAIMAVPAHDERDWEFAKQF+L+IIP
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  361  VLEGGNVAEAAYTEDGRHINSDFLDGLDKADAIAKMVAWLEDKEVGNEKVTYRLRDWLFS  420
            VLEGGNV EAA+TEDG HINSDFLDGLDKA AIAKMV WLE   VGNE+VTYRLRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  421  RQRYWGEPIPIIHWEDGTSTAVPENELPLVLPVTSDIRPSGTGESPLANLTDWLEVTRED  480
            RQRYWGEPIPIIHWEDGTSTAVPE+ELPLVLPVT DIRPSGTGESPLAN+TDWLEVTRED
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  481  GVKGRRETNTMPQWAGSSWYYLRYIDPKNDQALADPELLKQWLPVDIYVGGAEHAVLHLL  540
            GVKGRRETNTMPQWAGSSWYYLRYIDP N + LAD ELLKQWLPVDIYVGGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDHRGALVATDKVEKRDGSFFHIET  600
            YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRD RGALVATDKVEKRDGSFFH+ET
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660
            GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  661  LDRVYRLVTTREIVAENSGALDKVYNETVKAVTEQIETMKFNTAIAQLMIFVNAANKEDQ  720
            LDRVYRL+TT+EI  ENSGALDKVYNETVKAVTEQ++ MKFNTAIAQLM+FVNAANKED+
Sbjct  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  721  LFVDYAKGFVQLIAPFAPHLGEELWQMITQSDESIAHVAWPTWDESKLVENDVEIVVQIk  780
            LF DYAKGFVQLIAPFAPHLGEELWQ +T S+ESI+ V+WP+ DESKLVENDVEIVVQIK
Sbjct  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK  780

Query  781  gkvkaklvvakDLSREDLEAAALANEKVQAEIAGKDIVKVIAVPNKLVNIVVK  833
            GKVKAKLVVAKDLSRE+L+  ALANEKVQAEIAGKDI+KVIAVPNKLVNIV+K
Sbjct  781  GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

70) leuS in NC_018712


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1241 bits (4708),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 777/833 (94%), Positives = 808/833 (97%), Gaps = 0/833 (0%)

Query  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60
            MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   ILSRFKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120
            ILSRFKRAQG NVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WDREVNTTDPDYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180
            WDREVNTTDP+YYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKGSD  240
            GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVK++D
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDEITSPEQAEAVADYKRQASLKSDLARTDLAK  300
            KDFTVFTTRPDTLFGATYAVLAPEHALVD IT+++QAEAVADYKRQASLKSDLARTDLAK
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  301  EKTGVWTGSYAINPVNGKEVPIWIADYVLASYGTGAIMAVPAHDERDWEFAKQFDLEIIP  360
            EKTGVWTGSYAINPVNGKE+P+WIADYVLASYGTGAIMAVPAHDERDWEFAKQF+L+IIP
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  361  VLEGGNVAEAAYTEDGRHINSDFLDGLDKADAIAKMVAWLEDKEVGNEKVTYRLRDWLFS  420
            VLEGGNV EAA+TEDG HINSDFLDGLDKA AIAKMV WLE   VGNE+VTYRLRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  421  RQRYWGEPIPIIHWEDGTSTAVPENELPLVLPVTSDIRPSGTGESPLANLTDWLEVTRED  480
            RQRYWGEPIPIIHWEDGTSTAVPE+ELPLVLPVT DIRPSGTGESPLAN+TDWLEVTRED
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  481  GVKGRRETNTMPQWAGSSWYYLRYIDPKNDQALADPELLKQWLPVDIYVGGAEHAVLHLL  540
            GVKGRRETNTMPQWAGSSWYYLRYIDP N + LAD ELLKQWLPVDIYVGGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDHRGALVATDKVEKRDGSFFHIET  600
            YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRD RGALVATDKVEKRDGSFFH+ET
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660
            GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  661  LDRVYRLVTTREIVAENSGALDKVYNETVKAVTEQIETMKFNTAIAQLMIFVNAANKEDQ  720
            LDRVYRL+TT+EI  ENSGALDKVYNETVKAVTEQ++ MKFNTAIAQLM+FVNAANKED+
Sbjct  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  721  LFVDYAKGFVQLIAPFAPHLGEELWQMITQSDESIAHVAWPTWDESKLVENDVEIVVQIk  780
            LF DYAKGFVQLIAPFAPHLGEELWQ +T S+ESI+ V+WP+ DESKLVENDVEIVVQIK
Sbjct  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK  780

Query  781  gkvkaklvvakDLSREDLEAAALANEKVQAEIAGKDIVKVIAVPNKLVNIVVK  833
            GKVKAKLVVAKDLSRE+L+  ALANEKVQAEIAGKDI+KVIAVPNKLVNIV+K
Sbjct  781  GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

71) leuS in NC_019042


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1239 bits (4699),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 775/833 (94%), Positives = 805/833 (97%), Gaps = 0/833 (0%)

Query  1    MTFYDHKAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60
            MTFYDH AIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   ILSRFKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120
            ILSRFKRAQG NVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WDREVNTTDPDYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180
            WDREVNTTDP+YYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKGSD  240
            GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVK++D
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDEITSPEQAEAVADYKCQASLKSDLARTDLAK  300
            KDFTVFTTRPDTLFGATYAVLAPEHALVD IT+++QAEAVADYK QASLKSDLARTDLAK
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  301  EKTGVWTGSYAINPVNGKEMPIWIADYVLASYGTGAIMAVPAHDERDWEFAKQFDLEIIP  360
            EKTGVWTGSYAINPVNGKEMP+WIADYVLASYGTGAIMAVPAHDERDWEFAKQF+L+IIP
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  361  VLEGGNVAEAAYIEDGRHINSDFLDGLDKADAIAKMVAWLEDKEVGNEKVTYRLRDWLFS  420
            VLEGGNV EAA+ EDG HINSDFLDGLDKA AIAKMV WLE   VGNE+VTYRLRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  421  RQRYWGEPIPIIHWEDGTSTAVPENELPLVLPVTSDIRPSGTGESPLANLTDWLEVTRED  480
            RQRYWGEPIPIIHWEDGTSTAVPE+ELPLVLPVT DIRPSGTGESPLAN+TDWLEVTRED
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  481  GVKGRRETNTMPQWAGSSWYYLRYIDPKNDQALADPELLKQWLPVDIYVGGAEHAVLHLL  540
            GVKGRRETNTMPQWAGSSWYYLRYIDP N + LAD ELLKQWLPVDIYVGGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDHRGALVATDKVEKRDGSFFHIET  600
            YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRD RGALVATDKVEKRDGSFFH+ET
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660
            GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  661  LDRVYRLVTTREIVAENSGALDKVYNETVKAVTEQIETMKFNTAIAQLMIFVNAANKEDQ  720
            LDRVYRL+TT+EI  ENSGALDKVYNETVKAVTEQ++ MKFNTAIAQLM+FVNAANKED+
Sbjct  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  721  LFVDYAKGFVQLIAPFAPHLGEELWQMITQSDESIAHVAWPTWDESKLVENDVEIVVQIk  780
            LF DYAKGFVQLIAPFAPHLGEELWQ +T S+ESI+ V+WP+ DESKLVENDVEIVVQIK
Sbjct  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK  780

Query  781  gkvkaklvvakDLSREDLEAAALANEKVQAEIAGKDIVKVIAVPNKLVNIVVK  833
            GKVKAKLVVAKDLSRE+L+  ALANEKVQAEIAGKDI+KVIAVPNKLVNIV+K
Sbjct  781  GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

72) K710_2041 in NC_021314


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1231 bits (4671),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 758/833 (91%), Positives = 808/833 (97%), Gaps = 0/833 (0%)

Query  1    MTFYNHKDIEPKWQAFWADKHTFKTGMDTSKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60
            MTFY+H  IEPKWQAFWAD+HTFKTG D+SKPKFYALDMFPYPSGAGLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   ILSRFKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPADFTAENIANFKRQINALGFSYD  120
            ILSRFKRAQG NVLHPMGWDAFGLPAEQYAMDTGNDPA+FTAENIANFKRQINALGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180
            WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSSGANVTFKIKDSD  240
            GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKS+GANVTFK+KD+D
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  241  QEFTVFTTRPDTLFGATYAVLAPEHALVDAITSKEQAEAVAEYKRQASLKSDLARTDLAK  300
            ++FTVFTTRPDTLFGATYAVLAPEHALVDAIT+ +QAEAVA+YKRQASLKSDLARTDLAK
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  301  EKTGVWTGSYAINPVNGKEMPIWIADYVLASYGTGAIMAVPAHDDRDWDFAKQFNLDIIA  360
            EKTGVWTGSYAINPVNGKEMP+WIADYVLASYGTGAIMAVPAHD+RDW+FAKQFNLDII+
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  361  VLEGGNVDEAPYTEDGVHINSEFLNGLDKAQAMAKMIAWLEENGVGQEKITYRLRDWLFS  420
            VLEGGNV+EA++TEDG+HINS+FL+GLDKA A+AKM+ WLE +GVG+E++TYRLRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  421  RQRYWGEPIPIIHWEDGTSTAVPEGDLPLVLPVTKDIRPSGTGESPLANLTDWLEVVRED  480
            RQRYWGEPIPIIHWEDGTSTAVPE++LPLVLPVTKDIRPSGTGESPLAN+TDWLEV RED
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNDHALADPELLKQWLPVDIYVGGAEHAVLHLL  540
            GVKGRRETNTMPQWAGSSWYYLRYIDPHN + LAD ELLKQWLPVDIYVGGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDGRGALVATDKVEKRDGSFFHMET  600
            YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRD+RGALVATDKVEKRDGSFFH+ET
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  601  GEELEQAPAKMSKSLKNVVNPDDVVEAYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660
            GEELEQAPAKMSKSLKNVVNPDDVVE YGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  661  LDRVYRLITSKTIVTENSGALDKVYHETVKAVTEQVEAMKFNTAIAQLMVFVNAANKEDR  720
            LDRVYRLIT+K I  ENSGALDKVY+ETVKAVTEQV+ MKFNTAIAQLMVFVNAANKED+
Sbjct  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  721  LFADYAKGFVQLIAPFAPHLGEELWQILTDSQESISHVAWPVWDEAKLVENDVEIVVQIk  780
            LF+DYAKGFVQLIAPFAPHLGEELWQ LT S ESIS V+WP  DE+KLVENDVEIVVQIK
Sbjct  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK  780

Query  781  gkvkaklvvakdlakEELERIALSHDKVQAEIAGKDIVKVIVVPNKLVNIVVK  833
            GKVKAKLVVAKDL++EEL+ +AL+++KVQAEIAGKDI+KVI VPNKLVNIV+K
Sbjct  781  GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

73) leuS in NC_017621


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1227 bits (4656),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 728/815 (90%), Positives = 788/815 (97%), Gaps = 0/815 (0%)

Query  1    MSFYNHKEIEPKWQEFWAKNHTFKTGTDADKPNFYALDMFPYPSGAGLHVGHPEGYTATD  60
            M+FY+H  IEPKWQ FWA NHTFKTGTDA KP+FYALDMFPYPSGAGLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   ILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPADFTAENIANFKRQINALGFSYD  120
            ILSR+KRAQG NVLHPMGWDAFGLPAEQYAMDTGNDPA+FTAENIANFKRQINALGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180
            WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  181  GYPVVRKPMRQWMLKITAYAERLLNDLEDVDWPESIKDMQRNWIGKSTGANVTFKIKGTD  240
            GYPVVRKPMRQWMLKITAYAERLL+DLE+VDWPESIKDMQRNWIGKSTGANVTFK+K+TD
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  241  KDFTVFTTRPDTLFGATYAVLAPEHDLVDSITSPEQAEAVAEYKRQASLKSDLARTDLAK  300
            KDFTVFTTRPDTLFGATYAVLAPEH LVD+IT+++QAEAVA+YKRQASLKSDLARTDLAK
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  301  DKTGVWTGAYAINPVNGREIPIWISDYVLVSYGTGAIMAVPAHDERDWEFAKQFNLDIIS  360
            +KTGVWTG+YAINPVNG+E+P+WI+DYVL SYGTGAIMAVPAHDERDWEFAKQFNLDII+
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  361  VLEGGNVEEAPYTEDGAHINSDFLDGLNKEEAIAKMVAWLEENGVGQEKISYRLRDWLFS  420
            VLEGGNVEEA++TEDG HINSDFLDGL+K  AIAKMV WLE +GVG+E+++YRLRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  421  RQRYWGEPIPIIHWEDGTSTAVPENELPLVLPKTSDIKPSGTGESPLANLTDWLEVVRED  480
            RQRYWGEPIPIIHWEDGTSTAVPE+ELPLVLP T DI+PSGTGESPLAN+TDWLEV RED
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNDEKLADEDLLKAWLPVDIYIGGAEHAVLHLL  540
            GVKGRRETNTMPQWAGSSWYYLRYIDPHN EKLADE+LLK WLPVDIY+GGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  541  YARFWHKFLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFNIET  600
            YARFWHK LYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFF++ET
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  601  GEELEQAPAKMSKSLKNVVNPDDVVEQFGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660
            GEELEQAPAKMSKSLKNVVNPDDVVEQ+GADTLRVYEMFMGPLDASIAWSEEGLEGSRKF
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  661  LDRVYRLITTKEISSKNSGALDKVYNETVKTVTEHIEDLKFNTAIAQLMIFVNAANKEDK  720
            LDRVYRLITTKEI+  NSGALDKVYNETVK+VTE+++++KFNTAIAQLM+FVNAANKEDK
Sbjct  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  721  LYVEYAKGFVQLIAPFAPHLAEELWQGLTNTGQSISYVAWPTYDESKLVESEVEIVVQIK  780
            L+ +YAKGFVQLIAPFAPHL+EELWQ+LT +G+SISYV+WP+YDESKLVE++VEIVVQIK
Sbjct  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK  780

Query  781  GKVKARLTVAKDLTPAELEKVALADEKVQAEIAGQ  815
            GKVKA+L VAKDL+  EL+ VALA+EKVQAEIAG+
Sbjct  781  GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGK  815

74) leuS in NC_012470


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1221 bits (4631),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 770/833 (93%), Positives = 812/833 (98%), Gaps = 0/833 (0%)

Query  1    MTFYNHKAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60
            MTFY+H AIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   ILSRFKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120
            ILSRFKRAQG NVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WDREINTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180
            WDRE+NTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  181  GYPVVRKPMRQWMLKITAYAERLLADLEEVDWPESIKDMQRNWIGKSTGANvtfkvkdtd  240
            GYPVVRKPMRQWMLKITAYAERLL DLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  241  kdftvfttRPDTLFGATYAVLAPEHALVDSITTAEQAQAVAEYKRQASLKSDLARTDLAK  300
            KDFTVFTTRPDTLFGATYAVLAPEHALVD+ITT++QA+AVA+YKRQASLKSDLARTDLAK
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  301  EKTGVWTGAYAINPVNGKEMPIWIADYVLASYGTGAIMAVPAHDERDWAFAKQFNLEIIP  360
            EKTGVWTG+YAINPVNGKEMP+WIADYVLASYGTGAIMAVPAHDERDW FAKQFNL+IIP
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  361  VLEGGNVDEAAYTEDGIHINSDFLDGLDKACAIAKMVVWLEETGVGHEKVSYRLRDWLFS  420
            VLEGGNV+EAA+TEDG+HINSDFLDGLDKA AIAKMV WLE  GVG+E+V+YRLRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  421  RQRYWGEPIPIIHWEDGTSTAVPEQDLPLVLPVTKDIRPSGTGESPLANLTDWLEVTRED  480
            RQRYWGEPIPIIHWEDGTSTAVPE +LPLVLPVTKDIRPSGTGESPLAN+TDWLEVTRED
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNDKQLADKDLLKQWLPVDIYIGGAEHAVLHLL  540
            GVKGRRETNTMPQWAGSSWYYLRYIDPHN  +LAD +LLKQWLPVDIY+GGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDHRGALVATDKVDKRDGSFFHMET  600
            YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRD RGALVATDKV+KRDGSFFH+ET
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGARKF  660
            GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEG+RKF
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  661  LDRVYRLITTKEIVAENSGALDKAYHETVKAVTEQIEGMKFNTAIAQLMIFVNAANKEDK  720
            LDRVYRLITTKEI  ENSGALDK Y+ETVKAVTEQ++ MKFNTAIAQLM+FVNAANKEDK
Sbjct  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  721  LYVAYAKGFVQLLAPFAPHLGEELWQSLTASGQSISYVAWPTHDDSKLVENDVEIVVQIk  780
            L+  YAKGFVQL+APFAPHLGEELWQ+LTASG+SISYV+WP+ D+SKLVENDVEIVVQIK
Sbjct  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK  780

Query  781  gkvkaklvvakDLSREELEKVALAHDKIQAEIAGKEVIKVIAVPNKLVNIVVK  833
            GKVKAKLVVAKDLSREEL+ VALA++K+QAEIAGK++IKVIAVPNKLVNIV+K
Sbjct  781  GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

75) leuS in NC_015558


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1221 bits (4631),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 750/833 (91%), Positives = 806/833 (97%), Gaps = 0/833 (0%)

Query  1    MTTYNHKEIEPKWQAYWAANKNFKTGTDKSKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60
            MT Y+H  IEPKWQA+WA N  FKTGTD SKPKFYALDMFPYPSGAGLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   ILSRFKRSQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120
            ILSRFKR+QG NVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVAVNWVEELGTAIANEEVLPDGTSERG  180
            WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEV+VNWVEELGTAIANEEVLPDGTSERG
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240
            GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  241  QDFTVFTTRPDTLFGATYAVLAPEHAMVDTITSPEQSQAVADYKRQASLKSDLVRTDLAK  300
            +DFTVFTTRPDTLFGATYAVLAPEHA+VD+IT+++Q++AVADYKRQASLKSDL RTDLAK
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  301  EKTGVWTGAYAINPVNGQEMPIWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLEIIP  360
            EKTGVWTG+YAINPVNG+EMP+WIADYVLASYGTGAIMAVPAHDERDWEFAKQFNL+IIP
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  361  VLEGGNVQEAAYTEDGLHINSDFLNGLDKAEGMSKMVEWLEENQVGNEKVTYRLRDWLFS  420
            VLEGGNV+EAA+TEDGLHINSDFL+GLDKA +++KMVEWLE + VGNE+VTYRLRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  421  RQRYWGEPIPIIHWEDGTSTAVPEQDLPLVLPITKDIRPSGTGESPLANLTDWLEVVRED  480
            RQRYWGEPIPIIHWEDGTSTAVPE +LPLVLP+TKDIRPSGTGESPLAN+TDWLEV RED
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNDQALADPELLKEWLPVDMYIGGAEHAVLHLL  540
            GVKGRRETNTMPQWAGSSWYYLRYIDPHN + LAD ELLK+WLPVD+Y+GGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  541  YARFWHKVLYDLDVVPTKEPFQKLYNQGMILGTSYRDHRGALVASDKVEKRDGSFFNIET  600
            YARFWHKVLYDL+VVPTKEPFQKL+NQGMILGTSYRD RGALVA+DKVEKRDGSFF++ET
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660
            GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  661  LDRVYRLITSKEIIAENSGALDKVYHETVKAVTEQIDSMKFNTAIAQLMIFVNAANKEDQ  720
            LDRVYRLIT+KEI  ENSGALDKVY+ETVKAVTEQ+D MKFNTAIAQLM+FVNAANKED+
Sbjct  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  721  LFVDYAKGFVQLIAPFAPHLGEELWQVLTSSGQSLTYEAWPIWDETKLIENDVEIVVQIk  780
            LF DYAKGFVQLIAPFAPHLGEELWQ LT+SG+S++Y +WP  DE+KL+ENDVEIVVQIK
Sbjct  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK  780

Query  781  gkvkaklvvakdlskDQLEAIALANDKVQAEIAGKEIIKVIAVPNKLVNIVVK  833
            GKVKAKLVVAKDLS+++L+ +ALAN+KVQAEIAGK+IIKVIAVPNKLVNIV+K
Sbjct  781  GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

76) leuS in NC_009009


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1221 bits (4632),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 744/833 (90%), Positives = 811/833 (98%), Gaps = 0/833 (0%)

Query  5    MAYYNHKEIEPKWQKYWAEHHTFKTGTDKDKPNFYALDMFPYPSGAGLHVGHPEGYTATD  64
            M++Y+H  IEPKWQ +WA++HTFKTGTD  KP+FYALDMFPYPSGAGLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  65   ILSRYKRTQGYNVLHPMGWDAFGLPAEQYAMDTGNDPADFTAENIANFKRQINALGFSYD  124
            ILSR+KR+QG NVLHPMGWDAFGLPAEQYAMDTGNDPA+FTAENIANFKRQINALGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  125  WDREINTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  184
            WDRE+NTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  185  GYPVVRKPMRQWMLKITAYAERLLNDLEELDWPESIKDMQRNWIGKSTGANvtfkikdtd  244
            GYPVVRKPMRQWMLKITAYAERLL+DLEE+DWPESIKDMQRNWIGKSTGANVTFK+KDTD
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  245  kdftvfttRPDTLFGATYAVLAPEHALVDAITSAEQAQAVADYKHAASLKSDLARTDLAK  304
            KDFTVFTTRPDTLFGATYAVLAPEHALVDAIT+++QA+AVADYK+ ASLKSDLARTDLAK
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  305  DKTGVWTGAYAINPVNGKEIPIWIADYVLASYGTGAIMAVPAHDERDWEFAKQFDLEIIP  364
            +KTGVWTG+YAINPVNGKE+P+WIADYVLASYGTGAIMAVPAHDERDWEFAKQF+L+IIP
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  365  VLEGGNVAEAAYTEDGPHINSGFLDGLDKAAAIDKMVAWLEAEGVGNEKVTYRLRDWLFS  424
            VLEGGNV EAA+TEDG HINS+FLDGLDKA+AI KMV WLEAEGVGNE+VTYRLRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  425  RQRYWGEPIPIIHWEDGTSTAVPENELPLVLPVTKDIRPSGTGESPLANLTDWLEVTRED  484
            RQRYWGEPIPIIHWEDGTSTAVPE+ELPLVLPVTKDIRPSGTGESPLAN+TDWLEVTRED
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  485  GVKGRRETNTMPQWAGSSWYYLRYIDPHNNEKLADEELLKAWLPVDIYIGGAEHAVLHLL  544
            GVKGRRETNTMPQWAGSSWYYLRYIDPHN EKLADEELLK WLPVDIY+GGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  545  YARFWHKFLYDIGVVPTKEPFQKLFNQGMILGTSYRDSRCALVATDKVEKRDGSFFNIET  604
            YARFWHK LYD+GVVPTKEPFQKLFNQGMILGTSYRDSR ALVATDKVEKRDGSFF++ET
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  605  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  664
            GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  665  LDRVYRLFNSKELVTENSGALDKVYHETVKSVTEQIEELKFNTAIAQLMIFVNAANKEEK  724
            LDRVYRL+ +KE+  ENSGALDKVY+ETVK+VTEQ++++KFNTAIAQLM+FVNAANKE+K
Sbjct  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  725  LYVEYAKGFIQLLAPFAPHLAEELWQAVAQTGESISYVTWPTYDESKLVEAEVEIVVQIK  784
            L+ +YAKGF+QL+APFAPHL+EELWQA++ +GESISYV WP+YDESKLVE +VEIVVQIK
Sbjct  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK  780

Query  785  GKVRAKLVVAKDLSREELQEIALSDEKIKSEIAGKEIVKVISVPNKLVNIVVK  837
            GKV+AKLVVAKDLSREELQE+AL++EK+++EIAGK+I+KVI+VPNKLVNIV+K
Sbjct  781  GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

77) leuS in NC_009443


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1220 bits (4627),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 746/833 (90%), Positives = 805/833 (97%), Gaps = 0/833 (0%)

Query  7    MSFYNHKEIEPKWQEFWAKNHTFKTGTDAEKPNFYALDMFPYPSGAGLHVGHPEGYTATD  66
            M+FY+H  IEPKWQ FWA NHTFKTGTDA KP+FYALDMFPYPSGAGLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  67   ILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPADFTAENIANFKRQINALGFSYD  126
            ILSR+KRAQG NVLHPMGWDAFGLPAEQYAMDTGNDPA+FTAENIANFKRQINALGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  127  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  186
            WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  187  GYPVVRKPMRQWMLKITAYAERLLNDLEEVDWPESIKDMQRNWIGKSTGANvtfkikdtd  246
            GYPVVRKPMRQWMLKITAYAERLL+DLEEVDWPESIKDMQRNWIGKSTGANVTFK+KDTD
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  247  kdftvfttRPDTLFGATYAVLAPEHDLVDSITSAEQAEAVAEYKRQASLKSDLARTDLAK  306
            KDFTVFTTRPDTLFGATYAVLAPEH LVD+IT+++QAEAVA+YKRQASLKSDLARTDLAK
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  307  DKTGVWTGAYAINPVNGKEIPIWIADYVLASYGTGAIMAVPAHDERDWEFAKQFGLDIIP  366
            +KTGVWTG+YAINPVNGKE+P+WIADYVLASYGTGAIMAVPAHDERDWEFAKQF LDIIP
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  367  VLEGGNVEEAPYTEDGAHINSDFLDGLNKEEAIAKMVAWLEENGVGQEKISYRLRDWLFS  426
            VLEGGNVEEA++TEDG HINSDFLDGL+K  AIAKMV WLE +GVG+E+++YRLRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  427  RQRYWGEPIPIIHWEDGTSTAVPENELPLVLPKTSDIKPSGTGESPLANLTDWLEVVRED  486
            RQRYWGEPIPIIHWEDGTSTAVPE+ELPLVLP T DI+PSGTGESPLAN+TDWLEV RED
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  487  GVKGRRETNTMPQWAGSSWYYLRYIDPHNDEKLADEDLLKAWLPVDIYIGGAEHAVLHLL  546
            GVKGRRETNTMPQWAGSSWYYLRYIDPHN EKLADE+LLK WLPVDIY+GGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  547  YARFWHKFLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHMET  606
            YARFWHK LYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFH+ET
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  607  GEELEQAPAKMSKSLKNVVNPDDVVEQFGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  666
            GEELEQAPAKMSKSLKNVVNPDDVVEQ+GADTLRVYEMFMGPLDASIAWSEEGLEGSRKF
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  667  LDRVYRLLTTKELVAENSGALDKVYNETVKTVTEHIEDLKFNTAIAQLMIFVNAANKEDK  726
            LDRVYRL+TTKE+  ENSGALDKVYNETVK+VTE+++++KFNTAIAQLM+FVNAANKEDK
Sbjct  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  727  LYVDYAKGFVQLIAPFAPHLAEELWQGLANTGQSISYVAWPTYDESKLVESEVEIVVQIK  786
            L+ DYAKGFVQLIAPFAPHL+EELWQ+L+ +G+SISYV+WP+YDESKLVE++VEIVVQIK
Sbjct  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK  780

Query  787  GKVKARLTVAKDLAPAELEKVALADEKVQAEIAGQTVVKVISVPNKLVNIVVK  839
            GKVKA+L VAKDL+  EL+ VALA+EKVQAEIAG+ ++KVI+VPNKLVNIV+K
Sbjct  781  GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

78) leuS in NC_012926


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1220 bits (4628),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 746/833 (90%), Positives = 805/833 (97%), Gaps = 0/833 (0%)

Query  1    MSFYNHKEIEPKWQEFWAKNHTFKTGTDAEKPNFYALDMFPYPSGAGLHVGHPEGYTATD  60
            M+FY+H  IEPKWQ FWA NHTFKTGTDA KP+FYALDMFPYPSGAGLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   ILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPADFTAENIANFKRQINALGFSYD  120
            ILSR+KRAQG NVLHPMGWDAFGLPAEQYAMDTGNDPA+FTAENIANFKRQINALGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180
            WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  181  GYPVVRKPMRQWMLKITAYAERLLNDLEEVDWPESIKDMQRNWIGKSTGANvtfkikdtd  240
            GYPVVRKPMRQWMLKITAYAERLL+DLEEVDWPESIKDMQRNWIGKSTGANVTFK+KDTD
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  241  kdftvfttRPDTLFGATYAVLAPEHDLVDSITSAEQAEAVAEYKRQASLKSDLARTDLAK  300
            KDFTVFTTRPDTLFGATYAVLAPEH LVD+IT+++QAEAVA+YKRQASLKSDLARTDLAK
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  301  DKTGVWTGAYAINPVNGKEIPIWIADYVLASYGTGAIMAVPAHDERDWEFAKQFGLDIIP  360
            +KTGVWTG+YAINPVNGKE+P+WIADYVLASYGTGAIMAVPAHDERDWEFAKQF LDIIP
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  361  VLEGGNVEEAPYTEDGAHINSDFLDGLNKEEAIAKMVAWLEENGVGQEKISYRLRDWLFS  420
            VLEGGNVEEA++TEDG HINSDFLDGL+K  AIAKMV WLE +GVG+E+++YRLRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  421  RQRYWGEPIPIIHWEDGTSTAVPENELPLVLPKTSDIKPSGTGESPLANLTDWLEVVRED  480
            RQRYWGEPIPIIHWEDGTSTAVPE+ELPLVLP T DI+PSGTGESPLAN+TDWLEV RED
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNDEKLADEDLLKAWLPVDIYIGGAEHAVLHLL  540
            GVKGRRETNTMPQWAGSSWYYLRYIDPHN EKLADE+LLK WLPVDIY+GGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  541  YARFWHKFLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHMET  600
            YARFWHK LYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFH+ET
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  601  GEELEQAPAKMSKSLKNVVNPDDVVEQFGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660
            GEELEQAPAKMSKSLKNVVNPDDVVEQ+GADTLRVYEMFMGPLDASIAWSEEGLEGSRKF
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  661  LDRVYRLLTTKELVAENSGALDKVYNETVKTVTEHIEDLKFNTAIAQLMIFVNAANKEDK  720
            LDRVYRL+TTKE+  ENSGALDKVYNETVK+VTE+++++KFNTAIAQLM+FVNAANKEDK
Sbjct  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  721  LYVDYAKGFVQLIAPFAPHLAEELWQGLANTGQSISYVAWPTYDESKLVESEVEIVVQIK  780
            L+ DYAKGFVQLIAPFAPHL+EELWQ+L+ +G+SISYV+WP+YDESKLVE++VEIVVQIK
Sbjct  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK  780

Query  781  GKVKARLTVAKDLAPAELEKVALADEKVQAEIAGQTVVKVISVPNKLVNIVVK  833
            GKVKA+L VAKDL+  EL+ VALA+EKVQAEIAG+ ++KVI+VPNKLVNIV+K
Sbjct  781  GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

79) SSGZ1_1889 in NC_017617


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1220 bits (4627),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 746/833 (90%), Positives = 805/833 (97%), Gaps = 0/833 (0%)

Query  7    MSFYNHKEIEPKWQEFWAKNHTFKTGTDAEKPNFYALDMFPYPSGAGLHVGHPEGYTATD  66
            M+FY+H  IEPKWQ FWA NHTFKTGTDA KP+FYALDMFPYPSGAGLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  67   ILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPADFTAENIANFKRQINALGFSYD  126
            ILSR+KRAQG NVLHPMGWDAFGLPAEQYAMDTGNDPA+FTAENIANFKRQINALGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  127  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  186
            WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  187  GYPVVRKPMRQWMLKITAYAERLLNDLEEVDWPESIKDMQRNWIGKSTGANvtfkikdtd  246
            GYPVVRKPMRQWMLKITAYAERLL+DLEEVDWPESIKDMQRNWIGKSTGANVTFK+KDTD
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  247  kdftvfttRPDTLFGATYAVLAPEHDLVDSITSAEQAEAVAEYKRQASLKSDLARTDLAK  306
            KDFTVFTTRPDTLFGATYAVLAPEH LVD+IT+++QAEAVA+YKRQASLKSDLARTDLAK
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  307  DKTGVWTGAYAINPVNGKEIPIWIADYVLASYGTGAIMAVPAHDERDWEFAKQFGLDIIP  366
            +KTGVWTG+YAINPVNGKE+P+WIADYVLASYGTGAIMAVPAHDERDWEFAKQF LDIIP
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  367  VLEGGNVEEAPYTEDGAHINSDFLDGLNKEEAIAKMVAWLEENGVGQEKISYRLRDWLFS  426
            VLEGGNVEEA++TEDG HINSDFLDGL+K  AIAKMV WLE +GVG+E+++YRLRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  427  RQRYWGEPIPIIHWEDGTSTAVPENELPLVLPKTSDIKPSGTGESPLANLTDWLEVVRED  486
            RQRYWGEPIPIIHWEDGTSTAVPE+ELPLVLP T DI+PSGTGESPLAN+TDWLEV RED
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  487  GVKGRRETNTMPQWAGSSWYYLRYIDPHNDEKLADEDLLKAWLPVDIYIGGAEHAVLHLL  546
            GVKGRRETNTMPQWAGSSWYYLRYIDPHN EKLADE+LLK WLPVDIY+GGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  547  YARFWHKFLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHMET  606
            YARFWHK LYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFH+ET
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  607  GEELEQAPAKMSKSLKNVVNPDDVVEQFGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  666
            GEELEQAPAKMSKSLKNVVNPDDVVEQ+GADTLRVYEMFMGPLDASIAWSEEGLEGSRKF
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  667  LDRVYRLLTTKELVAENSGALDKVYNETVKTVTEHIEDLKFNTAIAQLMIFVNAANKEDK  726
            LDRVYRL+TTKE+  ENSGALDKVYNETVK+VTE+++++KFNTAIAQLM+FVNAANKEDK
Sbjct  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  727  LYVDYAKGFVQLIAPFAPHLAEELWQGLANTGQSISYVAWPTYDESKLVESEVEIVVQIK  786
            L+ DYAKGFVQLIAPFAPHL+EELWQ+L+ +G+SISYV+WP+YDESKLVE++VEIVVQIK
Sbjct  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK  780

Query  787  GKVKARLTVAKDLAPAELEKVALADEKVQAEIAGQTVVKVISVPNKLVNIVVK  839
            GKVKA+L VAKDL+  EL+ VALA+EKVQAEIAG+ ++KVI+VPNKLVNIV+K
Sbjct  781  GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

80) leuS in NC_017618


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1220 bits (4628),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 746/833 (90%), Positives = 805/833 (97%), Gaps = 0/833 (0%)

Query  1    MSFYNHKEIEPKWQEFWAKNHTFKTGTDAEKPNFYALDMFPYPSGAGLHVGHPEGYTATD  60
            M+FY+H  IEPKWQ FWA NHTFKTGTDA KP+FYALDMFPYPSGAGLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   ILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPADFTAENIANFKRQINALGFSYD  120
            ILSR+KRAQG NVLHPMGWDAFGLPAEQYAMDTGNDPA+FTAENIANFKRQINALGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180
            WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  181  GYPVVRKPMRQWMLKITAYAERLLNDLEEVDWPESIKDMQRNWIGKSTGANvtfkikdtd  240
            GYPVVRKPMRQWMLKITAYAERLL+DLEEVDWPESIKDMQRNWIGKSTGANVTFK+KDTD
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  241  kdftvfttRPDTLFGATYAVLAPEHDLVDSITSAEQAEAVAEYKRQASLKSDLARTDLAK  300
            KDFTVFTTRPDTLFGATYAVLAPEH LVD+IT+++QAEAVA+YKRQASLKSDLARTDLAK
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  301  DKTGVWTGAYAINPVNGKEIPIWIADYVLASYGTGAIMAVPAHDERDWEFAKQFGLDIIP  360
            +KTGVWTG+YAINPVNGKE+P+WIADYVLASYGTGAIMAVPAHDERDWEFAKQF LDIIP
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  361  VLEGGNVEEAPYTEDGAHINSDFLDGLNKEEAIAKMVAWLEENGVGQEKISYRLRDWLFS  420
            VLEGGNVEEA++TEDG HINSDFLDGL+K  AIAKMV WLE +GVG+E+++YRLRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  421  RQRYWGEPIPIIHWEDGTSTAVPENELPLVLPKTSDIKPSGTGESPLANLTDWLEVVRED  480
            RQRYWGEPIPIIHWEDGTSTAVPE+ELPLVLP T DI+PSGTGESPLAN+TDWLEV RED
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNDEKLADEDLLKAWLPVDIYIGGAEHAVLHLL  540
            GVKGRRETNTMPQWAGSSWYYLRYIDPHN EKLADE+LLK WLPVDIY+GGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  541  YARFWHKFLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHMET  600
            YARFWHK LYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFH+ET
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  601  GEELEQAPAKMSKSLKNVVNPDDVVEQFGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660
            GEELEQAPAKMSKSLKNVVNPDDVVEQ+GADTLRVYEMFMGPLDASIAWSEEGLEGSRKF
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  661  LDRVYRLLTTKELVAENSGALDKVYNETVKTVTEHIEDLKFNTAIAQLMIFVNAANKEDK  720
            LDRVYRL+TTKE+  ENSGALDKVYNETVK+VTE+++++KFNTAIAQLM+FVNAANKEDK
Sbjct  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  721  LYVDYAKGFVQLIAPFAPHLAEELWQGLANTGQSISYVAWPTYDESKLVESEVEIVVQIK  780
            L+ DYAKGFVQLIAPFAPHL+EELWQ+L+ +G+SISYV+WP+YDESKLVE++VEIVVQIK
Sbjct  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK  780

Query  781  GKVKARLTVAKDLAPAELEKVALADEKVQAEIAGQTVVKVISVPNKLVNIVVK  833
            GKVKA+L VAKDL+  EL+ VALA+EKVQAEIAG+ ++KVI+VPNKLVNIV+K
Sbjct  781  GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

81) leuS in NC_012925


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1220 bits (4628),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 746/833 (90%), Positives = 805/833 (97%), Gaps = 0/833 (0%)

Query  1    MSFYNHKEIEPKWQEFWAKNHTFKTGTDAEKPNFYALDMFPYPSGAGLHVGHPEGYTATD  60
            M+FY+H  IEPKWQ FWA NHTFKTGTDA KP+FYALDMFPYPSGAGLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   ILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPADFTAENIANFKRQINALGFSYD  120
            ILSR+KRAQG NVLHPMGWDAFGLPAEQYAMDTGNDPA+FTAENIANFKRQINALGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180
            WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  181  GYPVVRKPMRQWMLKITAYAERLLNDLEEVDWPESIKDMQRNWIGKSTGANvtfkikdtd  240
            GYPVVRKPMRQWMLKITAYAERLL+DLEEVDWPESIKDMQRNWIGKSTGANVTFK+KDTD
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  241  kdftvfttRPDTLFGATYAVLAPEHDLVDSITSAEQAEAVAEYKRQASLKSDLARTDLAK  300
            KDFTVFTTRPDTLFGATYAVLAPEH LVD+IT+++QAEAVA+YKRQASLKSDLARTDLAK
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  301  DKTGVWTGAYAINPVNGKEIPIWIADYVLASYGTGAIMAVPAHDERDWEFAKQFGLDIIP  360
            +KTGVWTG+YAINPVNGKE+P+WIADYVLASYGTGAIMAVPAHDERDWEFAKQF LDIIP
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  361  VLEGGNVEEAPYTEDGAHINSDFLDGLNKEEAIAKMVAWLEENGVGQEKISYRLRDWLFS  420
            VLEGGNVEEA++TEDG HINSDFLDGL+K  AIAKMV WLE +GVG+E+++YRLRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  421  RQRYWGEPIPIIHWEDGTSTAVPENELPLVLPKTSDIKPSGTGESPLANLTDWLEVVRED  480
            RQRYWGEPIPIIHWEDGTSTAVPE+ELPLVLP T DI+PSGTGESPLAN+TDWLEV RED
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNDEKLADEDLLKAWLPVDIYIGGAEHAVLHLL  540
            GVKGRRETNTMPQWAGSSWYYLRYIDPHN EKLADE+LLK WLPVDIY+GGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  541  YARFWHKFLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHMET  600
            YARFWHK LYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFH+ET
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  601  GEELEQAPAKMSKSLKNVVNPDDVVEQFGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660
            GEELEQAPAKMSKSLKNVVNPDDVVEQ+GADTLRVYEMFMGPLDASIAWSEEGLEGSRKF
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  661  LDRVYRLLTTKELVAENSGALDKVYNETVKTVTEHIEDLKFNTAIAQLMIFVNAANKEDK  720
            LDRVYRL+TTKE+  ENSGALDKVYNETVK+VTE+++++KFNTAIAQLM+FVNAANKEDK
Sbjct  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  721  LYVDYAKGFVQLIAPFAPHLAEELWQGLANTGQSISYVAWPTYDESKLVESEVEIVVQIK  780
            L+ DYAKGFVQLIAPFAPHL+EELWQ+L+ +G+SISYV+WP+YDESKLVE++VEIVVQIK
Sbjct  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK  780

Query  781  GKVKARLTVAKDLAPAELEKVALADEKVQAEIAGQTVVKVISVPNKLVNIVVK  833
            GKVKA+L VAKDL+  EL+ VALA+EKVQAEIAG+ ++KVI+VPNKLVNIV+K
Sbjct  781  GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

82) leuS in NC_018526


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1220 bits (4628),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 746/833 (90%), Positives = 805/833 (97%), Gaps = 0/833 (0%)

Query  1    MSFYNHKEIEPKWQEFWAKNHTFKTGTDAEKPNFYALDMFPYPSGAGLHVGHPEGYTATD  60
            M+FY+H  IEPKWQ FWA NHTFKTGTDA KP+FYALDMFPYPSGAGLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   ILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPADFTAENIANFKRQINALGFSYD  120
            ILSR+KRAQG NVLHPMGWDAFGLPAEQYAMDTGNDPA+FTAENIANFKRQINALGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180
            WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  181  GYPVVRKPMRQWMLKITAYAERLLNDLEEVDWPESIKDMQRNWIGKSTGANvtfkikdtd  240
            GYPVVRKPMRQWMLKITAYAERLL+DLEEVDWPESIKDMQRNWIGKSTGANVTFK+KDTD
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  241  kdftvfttRPDTLFGATYAVLAPEHDLVDSITSAEQAEAVAEYKRQASLKSDLARTDLAK  300
            KDFTVFTTRPDTLFGATYAVLAPEH LVD+IT+++QAEAVA+YKRQASLKSDLARTDLAK
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  301  DKTGVWTGAYAINPVNGKEIPIWIADYVLASYGTGAIMAVPAHDERDWEFAKQFGLDIIP  360
            +KTGVWTG+YAINPVNGKE+P+WIADYVLASYGTGAIMAVPAHDERDWEFAKQF LDIIP
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  361  VLEGGNVEEAPYTEDGAHINSDFLDGLNKEEAIAKMVAWLEENGVGQEKISYRLRDWLFS  420
            VLEGGNVEEA++TEDG HINSDFLDGL+K  AIAKMV WLE +GVG+E+++YRLRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  421  RQRYWGEPIPIIHWEDGTSTAVPENELPLVLPKTSDIKPSGTGESPLANLTDWLEVVRED  480
            RQRYWGEPIPIIHWEDGTSTAVPE+ELPLVLP T DI+PSGTGESPLAN+TDWLEV RED
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNDEKLADEDLLKAWLPVDIYIGGAEHAVLHLL  540
            GVKGRRETNTMPQWAGSSWYYLRYIDPHN EKLADE+LLK WLPVDIY+GGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  541  YARFWHKFLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHMET  600
            YARFWHK LYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFH+ET
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  601  GEELEQAPAKMSKSLKNVVNPDDVVEQFGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660
            GEELEQAPAKMSKSLKNVVNPDDVVEQ+GADTLRVYEMFMGPLDASIAWSEEGLEGSRKF
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  661  LDRVYRLLTTKELVAENSGALDKVYNETVKTVTEHIEDLKFNTAIAQLMIFVNAANKEDK  720
            LDRVYRL+TTKE+  ENSGALDKVYNETVK+VTE+++++KFNTAIAQLM+FVNAANKEDK
Sbjct  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  721  LYVDYAKGFVQLIAPFAPHLAEELWQGLANTGQSISYVAWPTYDESKLVESEVEIVVQIK  780
            L+ DYAKGFVQLIAPFAPHL+EELWQ+L+ +G+SISYV+WP+YDESKLVE++VEIVVQIK
Sbjct  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK  780

Query  781  GKVKARLTVAKDLAPAELEKVALADEKVQAEIAGQTVVKVISVPNKLVNIVVK  833
            GKVKA+L VAKDL+  EL+ VALA+EKVQAEIAG+ ++KVI+VPNKLVNIV+K
Sbjct  781  GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

83) NJAUSS_1917 in NC_020526


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1220 bits (4628),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 746/833 (90%), Positives = 805/833 (97%), Gaps = 0/833 (0%)

Query  1    MSFYNHKEIEPKWQEFWAKNHTFKTGTDAEKPNFYALDMFPYPSGAGLHVGHPEGYTATD  60
            M+FY+H  IEPKWQ FWA NHTFKTGTDA KP+FYALDMFPYPSGAGLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   ILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPADFTAENIANFKRQINALGFSYD  120
            ILSR+KRAQG NVLHPMGWDAFGLPAEQYAMDTGNDPA+FTAENIANFKRQINALGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180
            WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  181  GYPVVRKPMRQWMLKITAYAERLLNDLEEVDWPESIKDMQRNWIGKSTGANvtfkikdtd  240
            GYPVVRKPMRQWMLKITAYAERLL+DLEEVDWPESIKDMQRNWIGKSTGANVTFK+KDTD
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  241  kdftvfttRPDTLFGATYAVLAPEHDLVDSITSAEQAEAVAEYKRQASLKSDLARTDLAK  300
            KDFTVFTTRPDTLFGATYAVLAPEH LVD+IT+++QAEAVA+YKRQASLKSDLARTDLAK
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  301  DKTGVWTGAYAINPVNGKEIPIWIADYVLASYGTGAIMAVPAHDERDWEFAKQFGLDIIP  360
            +KTGVWTG+YAINPVNGKE+P+WIADYVLASYGTGAIMAVPAHDERDWEFAKQF LDIIP
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  361  VLEGGNVEEAPYTEDGAHINSDFLDGLNKEEAIAKMVAWLEENGVGQEKISYRLRDWLFS  420
            VLEGGNVEEA++TEDG HINSDFLDGL+K  AIAKMV WLE +GVG+E+++YRLRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  421  RQRYWGEPIPIIHWEDGTSTAVPENELPLVLPKTSDIKPSGTGESPLANLTDWLEVVRED  480
            RQRYWGEPIPIIHWEDGTSTAVPE+ELPLVLP T DI+PSGTGESPLAN+TDWLEV RED
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNDEKLADEDLLKAWLPVDIYIGGAEHAVLHLL  540
            GVKGRRETNTMPQWAGSSWYYLRYIDPHN EKLADE+LLK WLPVDIY+GGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  541  YARFWHKFLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHMET  600
            YARFWHK LYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFH+ET
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  601  GEELEQAPAKMSKSLKNVVNPDDVVEQFGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660
            GEELEQAPAKMSKSLKNVVNPDDVVEQ+GADTLRVYEMFMGPLDASIAWSEEGLEGSRKF
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  661  LDRVYRLLTTKELVAENSGALDKVYNETVKTVTEHIEDLKFNTAIAQLMIFVNAANKEDK  720
            LDRVYRL+TTKE+  ENSGALDKVYNETVK+VTE+++++KFNTAIAQLM+FVNAANKEDK
Sbjct  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  721  LYVDYAKGFVQLIAPFAPHLAEELWQGLANTGQSISYVAWPTYDESKLVESEVEIVVQIK  780
            L+ DYAKGFVQLIAPFAPHL+EELWQ+L+ +G+SISYV+WP+YDESKLVE++VEIVVQIK
Sbjct  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK  780

Query  781  GKVKARLTVAKDLAPAELEKVALADEKVQAEIAGQTVVKVISVPNKLVNIVVK  833
            GKVKA+L VAKDL+  EL+ VALA+EKVQAEIAG+ ++KVI+VPNKLVNIV+K
Sbjct  781  GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

84) leuS in NC_012924


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1220 bits (4628),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 746/833 (90%), Positives = 805/833 (97%), Gaps = 0/833 (0%)

Query  1    MSFYNHKEIEPKWQEFWAKNHTFKTGTDAEKPNFYALDMFPYPSGAGLHVGHPEGYTATD  60
            M+FY+H  IEPKWQ FWA NHTFKTGTDA KP+FYALDMFPYPSGAGLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   ILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPADFTAENIANFKRQINALGFSYD  120
            ILSR+KRAQG NVLHPMGWDAFGLPAEQYAMDTGNDPA+FTAENIANFKRQINALGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180
            WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  181  GYPVVRKPMRQWMLKITAYAERLLNDLEEVDWPESIKDMQRNWIGKSTGANvtfkikdtd  240
            GYPVVRKPMRQWMLKITAYAERLL+DLEEVDWPESIKDMQRNWIGKSTGANVTFK+KDTD
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  241  kdftvfttRPDTLFGATYAVLAPEHDLVDSITSAEQAEAVAEYKRQASLKSDLARTDLAK  300
            KDFTVFTTRPDTLFGATYAVLAPEH LVD+IT+++QAEAVA+YKRQASLKSDLARTDLAK
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  301  DKTGVWTGAYAINPVNGKEIPIWIADYVLASYGTGAIMAVPAHDERDWEFAKQFGLDIIP  360
            +KTGVWTG+YAINPVNGKE+P+WIADYVLASYGTGAIMAVPAHDERDWEFAKQF LDIIP
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  361  VLEGGNVEEAPYTEDGAHINSDFLDGLNKEEAIAKMVAWLEENGVGQEKISYRLRDWLFS  420
            VLEGGNVEEA++TEDG HINSDFLDGL+K  AIAKMV WLE +GVG+E+++YRLRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  421  RQRYWGEPIPIIHWEDGTSTAVPENELPLVLPKTSDIKPSGTGESPLANLTDWLEVVRED  480
            RQRYWGEPIPIIHWEDGTSTAVPE+ELPLVLP T DI+PSGTGESPLAN+TDWLEV RED
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNDEKLADEDLLKAWLPVDIYIGGAEHAVLHLL  540
            GVKGRRETNTMPQWAGSSWYYLRYIDPHN EKLADE+LLK WLPVDIY+GGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  541  YARFWHKFLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHMET  600
            YARFWHK LYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFH+ET
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  601  GEELEQAPAKMSKSLKNVVNPDDVVEQFGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660
            GEELEQAPAKMSKSLKNVVNPDDVVEQ+GADTLRVYEMFMGPLDASIAWSEEGLEGSRKF
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  661  LDRVYRLLTTKELVAENSGALDKVYNETVKTVTEHIEDLKFNTAIAQLMIFVNAANKEDK  720
            LDRVYRL+TTKE+  ENSGALDKVYNETVK+VTE+++++KFNTAIAQLM+FVNAANKEDK
Sbjct  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  721  LYVDYAKGFVQLIAPFAPHLAEELWQGLANTGQSISYVAWPTYDESKLVESEVEIVVQIK  780
            L+ DYAKGFVQLIAPFAPHL+EELWQ+L+ +G+SISYV+WP+YDESKLVE++VEIVVQIK
Sbjct  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK  780

Query  781  GKVKARLTVAKDLAPAELEKVALADEKVQAEIAGQTVVKVISVPNKLVNIVVK  833
            GKVKA+L VAKDL+  EL+ VALA+EKVQAEIAG+ ++KVI+VPNKLVNIV+K
Sbjct  781  GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

85) leuS in NC_017619


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1220 bits (4628),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 746/833 (90%), Positives = 805/833 (97%), Gaps = 0/833 (0%)

Query  1    MSFYNHKEIEPKWQEFWAKNHTFKTGTDAEKPNFYALDMFPYPSGAGLHVGHPEGYTATD  60
            M+FY+H  IEPKWQ FWA NHTFKTGTDA KP+FYALDMFPYPSGAGLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   ILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPADFTAENIANFKRQINALGFSYD  120
            ILSR+KRAQG NVLHPMGWDAFGLPAEQYAMDTGNDPA+FTAENIANFKRQINALGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180
            WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  181  GYPVVRKPMRQWMLKITAYAERLLNDLEEVDWPESIKDMQRNWIGKSTGANvtfkikdtd  240
            GYPVVRKPMRQWMLKITAYAERLL+DLEEVDWPESIKDMQRNWIGKSTGANVTFK+KDTD
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  241  kdftvfttRPDTLFGATYAVLAPEHDLVDSITSAEQAEAVAEYKRQASLKSDLARTDLAK  300
            KDFTVFTTRPDTLFGATYAVLAPEH LVD+IT+++QAEAVA+YKRQASLKSDLARTDLAK
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  301  DKTGVWTGAYAINPVNGKEIPIWIADYVLASYGTGAIMAVPAHDERDWEFAKQFGLDIIP  360
            +KTGVWTG+YAINPVNGKE+P+WIADYVLASYGTGAIMAVPAHDERDWEFAKQF LDIIP
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  361  VLEGGNVEEAPYTEDGAHINSDFLDGLNKEEAIAKMVAWLEENGVGQEKISYRLRDWLFS  420
            VLEGGNVEEA++TEDG HINSDFLDGL+K  AIAKMV WLE +GVG+E+++YRLRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  421  RQRYWGEPIPIIHWEDGTSTAVPENELPLVLPKTSDIKPSGTGESPLANLTDWLEVVRED  480
            RQRYWGEPIPIIHWEDGTSTAVPE+ELPLVLP T DI+PSGTGESPLAN+TDWLEV RED
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNDEKLADEDLLKAWLPVDIYIGGAEHAVLHLL  540
            GVKGRRETNTMPQWAGSSWYYLRYIDPHN EKLADE+LLK WLPVDIY+GGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  541  YARFWHKFLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHMET  600
            YARFWHK LYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFH+ET
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  601  GEELEQAPAKMSKSLKNVVNPDDVVEQFGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660
            GEELEQAPAKMSKSLKNVVNPDDVVEQ+GADTLRVYEMFMGPLDASIAWSEEGLEGSRKF
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  661  LDRVYRLLTTKELVAENSGALDKVYNETVKTVTEHIEDLKFNTAIAQLMIFVNAANKEDK  720
            LDRVYRL+TTKE+  ENSGALDKVYNETVK+VTE+++++KFNTAIAQLM+FVNAANKEDK
Sbjct  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  721  LYVDYAKGFVQLIAPFAPHLAEELWQGLANTGQSISYVAWPTYDESKLVESEVEIVVQIK  780
            L+ DYAKGFVQLIAPFAPHL+EELWQ+L+ +G+SISYV+WP+YDESKLVE++VEIVVQIK
Sbjct  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK  780

Query  781  GKVKARLTVAKDLAPAELEKVALADEKVQAEIAGQTVVKVISVPNKLVNIVVK  833
            GKVKA+L VAKDL+  EL+ VALA+EKVQAEIAG+ ++KVI+VPNKLVNIV+K
Sbjct  781  GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

86) KE3_0089 in NC_021900


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1219 bits (4624),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 758/833 (91%), Positives = 805/833 (97%), Gaps = 0/833 (0%)

Query  1    MVTYNHKEIEKKWQAYWADNHTFKTGTDADKPNFYALDMFPYPSGAGLHVGHPEGYTATD  60
            M  Y+H  IE KWQA+WADNHTFKTGTDA KP+FYALDMFPYPSGAGLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   ILSRFKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAKNIANFKRQINSLGFSYD  120
            ILSRFKRAQG NVLHPMGWDAFGLPAEQYAMDTGNDPAEFTA NIANFKRQIN+LGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180
            WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  181  GYPVVRKPMRQWMLKITAYAERLLNDLDDLDWPESIKDMQRNWIGKSTGANvtfkvkdtd  240
            GYPVVRKPMRQWMLKITAYAERLL+DL+++DWPESIKDMQRNWIGKSTGANVTFKVKDTD
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  241  kdftvfttRPDTLFGATYAVLAPEHPLVEAITTPEQAQAVADYKHQASLKSDLARTDLAK  300
            KDFTVFTTRPDTLFGATYAVLAPEH+LV+AITT++QA+AVADYK+QASLKSDLARTDLAK
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  301  EKTGVWTGSYAINPVNGKEMPIWIADYVLVSYGTGAIMAVPAHDTRDWEFAKQFNLEIIP  360
            EKTGVWTGSYAINPVNGKEMP+WIADYVL SYGTGAIMAVPAHD RDWEFAKQFNL+IIP
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  361  VLEGGNVEEEAYTEDGLHINSGFLDGLDKAQAIDKMVEWLEAEGVGNKKVTYRLRDWLFS  420
            VLEGGNVEE A+TEDGLHINS+FLDGLDKA AI KMVEWLEAEGVGN +VTYRLRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  421  RQRYWGEPIPIIHWEDGTTTAVPEDQLPLVLPVTKDIKPSGTGESPLANLTDWLEVTRED  480
            RQRYWGEPIPIIHWEDGT+TAVPE +LPLVLPVTKDI+PSGTGESPLAN+TDWLEVTRED
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  481  GVKGRRETNTMPQWAGSSWYFLRYIDPHNDEKLADEELLKAWLPVDIYIGGAEHAVLHLL  540
            GVKGRRETNTMPQWAGSSWY+LRYIDPHN EKLADEELLK WLPVDIY+GGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  541  YARFWHKFLYDLGVVPTKEPFQKLFNQGMILGTSYRDHRGALVATDKVEKRDGSFFHIET  600
            YARFWHK LYDLGVVPTKEPFQKLFNQGMILGTSYRD RGALVATDKVEKRDGSFFH+ET
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  601  GEKLEQAPAKMSKSLKNVVNPDDVVEHYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660
            GE LEQAPAKMSKSLKNVVNPDDVVE+YGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  661  LDRVYRLLTTKEIVAENNGNLDKVYNETVKAVTEQLETMKFNTAIAQLMVFVNAANKEDK  720
            LDRVYRL+TTKEI  EN+G LDKVYNETVKAVTEQ++ MKFNTAIAQLMVFVNAANKEDK
Sbjct  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  721  LFADYAKGFVQLLAPFAPHLSEELWQTLTQSGESISYVAWPTWDEAKLVENDVEIVIQIK  780
            LF+DYAKGFVQL+APFAPHL+EELWQ+LT SGESISYV+WP+ DE+KLVENDVEIV+QIK
Sbjct  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK  780

Query  781  GKVRAKLVVPKDSSREELEKLALANDKIQAEITGKDIIKVIAVPNKLVNIVVK  833
            GKV+AKLVV+KD SREEL+ +ALAN+K+QAEI+GKDIIKVIAVPNKLVNIV+K
Sbjct  781  GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

87) leuS in NC_017620


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1219 bits (4624),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 744/833 (90%), Positives = 807/833 (97%), Gaps = 0/833 (0%)

Query  1    MSFYNHKEIEPKWQGFWAKNHTFKTGTDAAKPNFYALDMFPYPSGAGLHVGHPEGYTATD  60
            M+FY+H  IEPKWQ+FWA NHTFKTGTDA+KP+FYALDMFPYPSGAGLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   ILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPADFTAENIANFKRQINALGFSYD  120
            ILSR+KRAQG NVLHPMGWDAFGLPAEQYAMDTGNDPA+FTAENIANFKRQINALGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180
            WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  181  GYPVVRKPMRQWMLKITAYAERLLNDLEEVDWPESIKDMQRNWIGKSTGANvtfkikdtd  240
            GYPVVRKPMRQWMLKITAYAERLL+DLEEVDWPESIKDMQRNWIGKSTGANVTFK+KDTD
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  241  kdftvfttRPDTLFGATYAVLAPEHDLVDSITSPEQTEAVAEYKRQASLKSDLARTDLAK  300
            KDFTVFTTRPDTLFGATYAVLAPEH LVD+IT+++Q+EAVA+YKRQASLKSDLARTDLAK
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  301  DKTGVWTGAYAINPVNGKEIPIWIADYVLASYGTGAIMAVPAHDERDWEFAKQFGLDIIP  360
            +KTGVWTG+YAINPVNGKE+P+WIADYVLASYGTGAIMAVPAHDERDWEFAKQF LDIIP
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  361  VLEGGNVEEAPYTEDGAHINSDFLDGLNKEEAIAKMVAWLEENGVGQEKISYRLRDWLFS  420
            VLEGGNVEEA++TEDG HINSDFLDGL+K  AIAKMV WLE +GVG+E+++YRLRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  421  RQRYWGEPIPIIHWEDGTSTAVPENELPLVLPKTSDIKPSGTGESPLANLTDWLEVVRED  480
            RQRYWGEPIPIIHWEDGTSTAVPE+ELPLVLP T DI+PSGTGESPLAN+TDWLEV RED
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNDEKLADEDLLKAWLPVDIYIGGAEHAVLHLL  540
            GVKGRRETNTMPQWAGSSWYYLRYIDPHN EKLADE+LLK WLPVDIY+GGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  541  YARFWHKFLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFNIET  600
            YARFWHK LYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFF++ET
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  601  GEELEQAPAKMSKSLKNVVNPDDVVEQFGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660
            GEELEQAPAKMSKSLKNVVNPDDVVEQ+GADTLRVYEMFMGPLDASIAWSEEGLEGSRKF
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  661  LDRVYRLLTTKELAAENSGALDKVYNETVKTVTEHIEDLKFNTAIAQLMIFVNAANKEDK  720
            LDRVYRL+TTKE++ ENSGALDKVYNETVK+VTE+++++KFNTAIAQLM+FVNAANKEDK
Sbjct  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  721  LYVEYAKGFVQLIAPFAPHLAEELWQGLTNTGQSISYVAWPTYDESKLVESEVEIVVQIK  780
            L+ +YAKGFVQLIAPFAPHL+EELWQ+LT +G+SISYV+WP+YDESKLVE++VEIVVQIK
Sbjct  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK  780

Query  781  GKVKARLTVAKDLAPAELEKVALADEKVQAEIAGQTVVKVITVPNKLVNIVTK  833
            GKVKA+L VAKDL+  EL+ VALA+EKVQAEIAG+ ++KVI+VPNKLVNIV K
Sbjct  781  GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

88) leuS in NC_009442


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1218 bits (4622),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 745/833 (90%), Positives = 804/833 (97%), Gaps = 0/833 (0%)

Query  7    MSFYNHKEIEPKWQEFWAKNHTFKTGTDAEKPNFYALDMFPYPSGAGLHVGHPEGYTATD  66
            M+FY+H  IEPKWQ FWA NHTFKTGTDA KP+FYALDMFPYPSGAGLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  67   ILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPADFTAENIANFKRQINALGFSYD  126
            ILSR+KRAQG NVLHPMGWDAFGLPAEQYAMDTGNDPA+FTAENIANFKRQINALGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  127  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  186
            WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  187  GYPVVRKPMRQWMLKITAYAERLLNDLEEVDWPESIKDMQRNWIGKSTGANvtfkikdtd  246
            GYPVVRKPMRQWMLKITAYAERLL+DLEEVDWPESIKDMQRNWIGKSTGANVTFK+KDTD
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  247  kdftvfttRPDTLFGATYAVLAPEHDLVDSITSAEQAEAVAEYKRQASLKSDLARTDLAT  306
            KDFTVFTTRPDTLFGATYAVLAPEH LVD+IT+++QAEAVA+YKRQASLKSDLARTDLA 
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  307  DKTGVWTGAYAINPVNGKEIPIWIADYVLASYGTGAIMAVPAHDERDWEFAKQFGLDIIP  366
            +KTGVWTG+YAINPVNGKE+P+WIADYVLASYGTGAIMAVPAHDERDWEFAKQF LDIIP
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  367  VLEGGNVEEAPYTEDGAHINSDFLDGLNKEEAIAKMVAWLEENGVGQEKISYRLRDWLFS  426
            VLEGGNVEEA++TEDG HINSDFLDGL+K  AIAKMV WLE +GVG+E+++YRLRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  427  RQRYWGEPIPIIHWEDGTSTAVPENELPLVLPKTSDIKPSGTGESPLANLTDWLEVVRED  486
            RQRYWGEPIPIIHWEDGTSTAVPE+ELPLVLP T DI+PSGTGESPLAN+TDWLEV RED
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  487  GVKGRRETNTMPQWAGSSWYYLRYIDPHNDEKLADEDLLKAWLPVDIYIGGAEHAVLHLL  546
            GVKGRRETNTMPQWAGSSWYYLRYIDPHN EKLADE+LLK WLPVDIY+GGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  547  YARFWHKFLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHMET  606
            YARFWHK LYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFH+ET
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  607  GEELEQAPAKMSKSLKNVVNPDDVVEQFGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  666
            GEELEQAPAKMSKSLKNVVNPDDVVEQ+GADTLRVYEMFMGPLDASIAWSEEGLEGSRKF
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  667  LDRVYRLLTTKELVAENSGALDKVYNETVKTVTEHIEDLKFNTAIAQLMIFVNAANKEDK  726
            LDRVYRL+TTKE+  ENSGALDKVYNETVK+VTE+++++KFNTAIAQLM+FVNAANKEDK
Sbjct  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  727  LYVDYAKGFVQLIAPFAPHLAEELWQGLANTGQSISYVAWPTYDESKLVESEVEIVVQIK  786
            L+ DYAKGFVQLIAPFAPHL+EELWQ+L+ +G+SISYV+WP+YDESKLVE++VEIVVQIK
Sbjct  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK  780

Query  787  GKVKARLTVAKDLAPAELEKVALADEKVQAEIAGQTVVKVISVPNKLVNIVVK  839
            GKVKA+L VAKDL+  EL+ VALA+EKVQAEIAG+ ++KVI+VPNKLVNIV+K
Sbjct  781  GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

89) leuS in NC_012471


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1217 bits (4616),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 767/833 (93%), Positives = 809/833 (98%), Gaps = 0/833 (0%)

Query  1    MTFYNHKAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60
            MTFY+H AIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   ILSRFKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120
            ILSRFKRAQG NVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WDREINTTDPSYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180
            WDRE+NTTDP+YYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  181  GYPVVRKPMRQWMLKITAYAERLLADLEEVDWPESIKDMQRNWIGKSTGANvtfkvkdtd  240
            GYPVVRKPMRQWMLKITAYAERLL DLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  241  kdftvfttRPDTLFGATYAVLAPEHALVDSITTAEQAQAVAEYKRQASLKSDLARTDLAK  300
            KDFTVFTTRPDTLFGATYAVLAPEHALVD+ITT++QA+AVA+YKRQASLKSDLARTDLAK
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  301  EKTGVWTGAYAINPVNGKEMPIWIADYVLASYGTGAIMAVPAHDERDWAFAKQFNLEIIP  360
            EKTGVWTG+YAINPVNGKEMP+WIADYVLASYGTGAIMAVPAHDERDW FAKQFNL+IIP
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  361  VLEGGNVDEAAYTEDGIHINSDFLDGLDKACAIAKMVAWLEETGVGHEKVSYRLRDWLFS  420
            VLEGGNV+EAA+TEDG+HINSDFLDGLDKA AIAKMV WLE  GVG+E+V+YRLRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  421  RQRYWGEPIPIIHWEDGTSTAVPEQDLPLVLPVTKDIRPSGTGESPLANLTDWLEVTRED  480
            RQRYWGEPIPIIHWEDGTSTAVPE +LPLVLPVTKDIRPSGTGESPLAN+TDWLEVTRED
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNDEQLADKDLLKQWLPVDIYIGGAEHAVLHLL  540
            GVKGRRETNTMPQWAGSSWYYLRYIDPHN E+LAD +LLKQWLPVDIY+GGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDHRGALVATDKVDKRDGSFFHMET  600
            YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRD RGALVATDKV+KRDGSFFH+ET
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGARKF  660
            GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEG+RKF
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  661  LDRVYRLITTKEIVAENSGALDKAYHETVKAVTEQIEGMKFNTAIAQLMIFVNAANKEDE  720
            LDRVYRLITTKEI  ENSGALDK Y+ETVKAVTEQ++ MKFNTAIAQLM+FVNAANKED 
Sbjct  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  721  LYVAYAKGFVQLLAPFAPHLGEELWQILTASGQSISYVAWPTHDDSKLVENDVEIVVQIk  780
            L+  YAKGFVQL+APFAPHLGEELWQ LTASG+SISYV+WP+ D+SKLVENDVEIVVQIK
Sbjct  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK  780

Query  781  gkvkaklvvakDLSREELEKVALAHDKIQAEIAGKEVAKVIVVPNKLVNIVVK  833
            GKVKAKLVVAKDLSREEL+ VALA++K+QAEIAGK++ KVI VPNKLVNIV+K
Sbjct  781  GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

90) leuS in NC_009785


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1217 bits (4615),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 744/833 (90%), Positives = 809/833 (98%), Gaps = 0/833 (0%)

Query  1    MSTYNHREIEPKWQKYWAEHHTFKTGTDKDKPNFYALDMFPYPSGAGLHVGHPEGYTATD  60
            M+ Y+H  IEPKWQ +WA++HTFKTGTD  KP+FYALDMFPYPSGAGLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   ILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPADFTAENIANFKRQINALGFSYD  120
            ILSR+KRAQG NVLHPMGWDAFGLPAEQYAMDTGNDPA+FTAENIANFKRQINALGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180
            WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  181  GYPVVRKPMRQWMLKITAYAERLLNDLEELDWPESIKDMQRNWIGKSTGANvtfkikdtd  240
            GYPVVRKPMRQWMLKITAYAERLL+DLEE+DWPESIKDMQRNWIGKSTGANVTFK+KDTD
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  241  kdftvfttRPDTLFGATYAVLAPEHALVDVITSAEQAQAVADYKHAASLKSDLARTDLAK  300
            KDFTVFTTRPDTLFGATYAVLAPEHALVD IT+++QA+AVADYK+ ASLKSDLARTDLAK
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  301  EKTGVWTGAYAINPVNGKEIPIWIADYVLASYGTGAIMAVPAHDERDWEFAKQFDLEIIP  360
            EKTGVWTG+YAINPVNGKE+P+WIADYVLASYGTGAIMAVPAHDERDWEFAKQF+L+IIP
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  361  VLEGGNVADAAYTEDGPHINSGFLDGLDKAAAIEKMVAWLEKEGVGNEKVTYRLRDWLFS  420
            VLEGGNV +AA+TEDG HINS+FLDGLDKA+AI KMV WLE EGVGNE+VTYRLRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANLTDWLEVTRED  480
            RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLAN+TDWLEVTRED
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNNEKLADEDLLKAWLPVDIYIGGAEHAVLHLL  540
            GVKGRRETNTMPQWAGSSWYYLRYIDPHN EKLADE+LLK WLPVDIY+GGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  541  YARFWHKFLYDLGVVPTKEPFQKLFNQGMILGTSYRDHRGALVATDKVEKRDGSFFNIET  600
            YARFWHK LYDLGVVPTKEPFQKLFNQGMILGTSYRD RGALVATDKVEKRDGSFF++ET
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660
            GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  661  LDRVYRLLNTKELVTENSGALDKVYHETVKSVTEQLEELKFNTAIAQLMIFVNAANKEEK  720
            LDRVYRL+ TKE+  ENSGALDKVY+ETVK+VTEQ++++KFNTAIAQLM+FVNAANKE+K
Sbjct  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  721  LYVEYAKGFIQLLAPFAPHLAEELWQAVAQTDESISYVAWPTYDESKLVEAEVEIVVQIK  780
            L+ +YAKGF+QL+APFAPHL+EELWQA++ ++ESISYV+WP+YDESKLVE +VEIVVQIK
Sbjct  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK  780

Query  781  GKVRAKLVVAKDLSREELQEIALADEKIKSEIADKEVVKVISVPNKLVNIVVK  833
            GKV+AKLVVAKDLSREELQE+ALA+EK+++EIA+K+++KVI+VPNKLVNIV+K
Sbjct  781  GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

91) leuS in NC_017622


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1217 bits (4616),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 744/833 (90%), Positives = 803/833 (97%), Gaps = 0/833 (0%)

Query  1    MSFYNHKEIEPKWQEFWAKNHTFKTGTDAEKPNFYALDMFPYPSGAGLHVGHPEGYTATD  60
            M+FY+H  IEPKWQ FWA NHTFKTGTDA KP+FYALDMFPYPSGAGLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   ILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPADFTAENIANFKRQINALGFSYD  120
            ILSR+KRAQG NVLHPMGWDAFGLPAEQYAMDTGNDPA+FTAENIANFKRQINALGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180
            WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  181  GYPVVRKPMRQWMLKKPAYAERLLNDLEEVDWPESIKDMQRNWIGKSTGANvtfkikdtd  240
            GYPVVRKPMRQWMLK  AYAERLL+DLEEVDWPESIKDMQRNWIGKSTGANVTFK+KDTD
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  241  kdftvfttRPDTLFGATYAVLAPEHDLVDSITSAEQAEAVAEYKRQASLKSDLARTDLAK  300
            KDFTVFTTRPDTLFGATYAVLAPEH LVD+IT+++QAEAVA+YKRQASLKSDLARTDLAK
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  301  DKTGVWTGAYAINPVNGKEIPIWIADYVLASYGTGAIMAVPAHDERDWEFAKQFGLDIIP  360
            +KTGVWTG+YAINPVNGKE+P+WIADYVLASYGTGAIMAVPAHDERDWEFAKQF LDIIP
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  361  VLEGGNVEEAPYTEDGAHINSDFLDGLNKEEAIAKMVAWLEENGVGQEKISYRLRDWLFS  420
            VLEGGNVEEA++TEDG HINSDFLDGL+K  AIAKMV WLE +GVG+E+++YRLRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  421  RQRYWGEPIPIIHWEDGTSTAVPENELPLVLPKTSDIKPSGTGESPLANLTDWLEVVRED  480
            RQRYWGEPIPIIHWEDGTSTAVPE+ELPLVLP T DI+PSGTGESPLAN+TDWLEV RED
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNDEKLADEDLLKAWLPVDIYIGGAEHAVLHLL  540
            GVKGRRETNTMPQWAGSSWYYLRYIDPHN EKLADE+LLK WLPVDIY+GGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  541  YARFWHKFLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHMET  600
            YARFWHK LYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFH+ET
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  601  GEELEQAPAKMSKSLKNVVNPDDVVEQFGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660
            GEELEQAPAKMSKSLKNVVNPDDVVEQ+GADTLRVYEMFMGPLDASIAWSEEGLEGSRKF
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  661  LDRVYRLLTTKELVAENSGALDKVYNETVKTVTEHIEDLKFNTAIAQLMIFVNAANKEDK  720
            LDRVYRL+TTKE+  ENSGALDKVYNETVK+VTE+++++KFNTAIAQLM+FVNAANKEDK
Sbjct  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  721  LYVDYAKGFVQLIAPFAPHLAEELWQGLANTGQSISYVAWPTYDESKLVESEVEIVVQIK  780
            L+ DYAKGFVQLIAPFAPHL+EELWQ+L+ +G+SISYV+WP+YDESKLVE++VEIVVQIK
Sbjct  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK  780

Query  781  GKVKARLTVAKDLAPAELEKVALADEKVQAEIAGQTVVKVISVPNKLVNIVVK  833
            GKVKA+L VAKDL+  EL+ VALA+EKVQAEIAG+ ++KVI+VPNKLVNIV+K
Sbjct  781  GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

92) leuS in NC_015433


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1217 bits (4615),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 743/833 (90%), Positives = 806/833 (97%), Gaps = 0/833 (0%)

Query  1    MSFYNHKEIEPKWQGFWAKNHTFKTGTDAAKPNFYALDMFPYPSGAGLHVGHPEGYTATD  60
            M+FY+H  IEPKWQ+FWA NHTFKTGTDA+KP+FYALDMFPYPSGAGLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   ILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPADFTAENIANFKRQINALGFSYD  120
            ILSR+KRAQG NVLHPMGWDAFGLPAEQYAMDTGNDPA+FTAENIANFKRQINALGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180
            WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  181  GYPVVRKPMRQWMLKITAYAERLLNDLEEVDWPESIKDMQRNWIGKSTGANvtfkikdtd  240
            GYPVVRKPMRQWMLKITAYAERLL+DLEEVDWPESIKDMQRNWIGKSTGANVTFK+KDTD
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  241  kdftvfttRPDTLFGATYAVLAPEHDLVDSITSPEQTEAVAEYKRQASLKSDLARTDLAK  300
            KDFTVFTTRPDTLFGATYAVLAPEH LVD+IT+++Q+EAVA+YKRQASLKSDLARTDLAK
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  301  DKTGVWTGAYAINPVNGKEIPIWIADYVLASYRTGAIMAVPAHDERDWEFAKQFGLDIIP  360
            +KTGVWTG+YAINPVNGKE+P+WIADYVLASY TGAIMAVPAHDERDWEFAKQF LDIIP
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  361  VLEGGNVEEAPYTEDGAHINSDFLDGLNKEEAIAKMVAWLEENGVGQEKISYRLRDWLFS  420
            VLEGGNVEEA++TEDG HINSDFLDGL+K  AIAKMV WLE +GVG+E+++YRLRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  421  RQRYWGEPIPIIHWEDGTSTAVPENELPLVLPKTSDIKPSGTGESPLANLTDWLEVVRED  480
            RQRYWGEPIPIIHWEDGTSTAVPE+ELPLVLP T DI+PSGTGESPLAN+TDWLEV RED
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNDEKLADEDLLKAWLPVDIYIGGAEHAVLHLL  540
            GVKGRRETNTMPQWAGSSWYYLRYIDPHN EKLADE+LLK WLPVDIY+GGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  541  YARFWHKFLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFNIET  600
            YARFWHK LYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFF++ET
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  601  GEELEQAPAKMSKSLKNVVNPDDVVEQFGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660
            GEELEQAPAKMSKSLKNVVNPDDVVEQ+GADTLRVYEMFMGPLDASIAWSEEGLEGSRKF
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  661  LDRVYRLLTTKELAAENSGALDKVYNETVKTVTEHIEDLKFNTAIAQLMIFVNAANKEDK  720
            LDRVYRL+TTKE++ ENSGALDKVYNETVK+VTE+++++KFNTAIAQLM+FVNAANKEDK
Sbjct  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  721  LYVEYAKGFVQLIAPFAPHLAEELWQGLTNTGQSISYVAWPTYDESKLVESEVEIVVQIK  780
            L+ +YAKGFVQLIAPFAPHL+EELWQ+LT +G+SISYV+WP+YDESKLVE++VEIVVQIK
Sbjct  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK  780

Query  781  GKVKARLTVAKDLAPAELEKVALADEKVQAEIAGQTVVKVITVPNKLVNIVTK  833
            GKVKA+L VAKDL+  EL+ VALA+EKVQAEIAG+ ++KVI+VPNKLVNIV K
Sbjct  781  GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

93) larS in NC_017582


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1216 bits (4614),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 766/833 (92%), Positives = 809/833 (98%), Gaps = 0/833 (0%)

Query  1    MTFYNHKAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60
            MTFY+H AIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   ILSRFKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120
            ILSRFKRAQG NVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WDREINTTDPSYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180
            WDRE+NTTDP+YYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  181  GYPVVRKPMRQWMLKITAYAERLLADLEEVDWPESIKDMQRNWIGKSTGANvtfkvkdtd  240
            GYPVVRKPMRQWMLKITAYAERLL DLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  241  kdftvfttRPDTLFGATYAVLAPEHALVDSITTAEQAAAVAEYKRQASLKSDLARTDLAK  300
            KDFTVFTTRPDTLFGATYAVLAPEHALVD+ITT++QA AVA+YKRQASLKSDLARTDLAK
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  301  EKTGVWTGAYAINPVNGKEMPIWIADYVLASYGTGAIMAVPAHDERDWAFAKQFNLEIIP  360
            EKTGVWTG+YAINPVNGKEMP+WIADYVLASYGTGAIMAVPAHDERDW FAKQFNL+IIP
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  361  VLEGGNVDEAAYTEDGIHINSGFLDGLDKACAITKMVAWLEETGVGHEKVSYRLRDWLFS  420
            VLEGGNV+EAA+TEDG+HINS+FLDGLDKA AI+KMV WLE  GVG+E+V+YRLRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  421  RQRYWGEPIPIIHWEDGTSTAVPEQDLPLVLPVTKDIRPSGTGESPLANLTDWLEVIRED  480
            RQRYWGEPIPIIHWEDGTSTAVPE +LPLVLPVTKDIRPSGTGESPLAN+TDWLEV RED
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNDEQLADKDLLKQWLPVDIYIGGAEHAVLHLL  540
            GVKGRRETNTMPQWAGSSWYYLRYIDPHN E+LAD +LLKQWLPVDIY+GGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDHRGALVATDKVDKRDGSFFHMET  600
            YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRD RGALVATDKV+KRDGSFFH+ET
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGARKF  660
            GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEG+RKF
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  661  LDRVYRLITTKEIVAENSGALDKAYHETVKAVTEQIEGMKFNTAIAQLMIFVNAANKEDE  720
            LDRVYRLITTKEI  ENSGALDK Y+ETVKAVTEQ++ MKFNTAIAQLM+FVNAANKED 
Sbjct  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  721  LYVAYAKGFVQLLAPFAPHLGEELWQILTASGQSISYVAWPTHDDSKLVENDVEIVVQIk  780
            L+  YAKGFVQL+APFAPHLGEELWQ LTASG+SISYV+WP+ D+SKLVENDVEIVVQIK
Sbjct  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK  780

Query  781  gkvkaklvvakDLSREELEKVALAHDKIQAEIAGKEVIKVIAVPNKLVNIVVK  833
            GKVKAKLVVAKDLSREEL+ VALA++K+QAEIAGK++IKVIAVPNKLVNIV+K
Sbjct  781  GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

94) leuS in NC_011134


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1215 bits (4609),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 765/833 (92%), Positives = 808/833 (97%), Gaps = 0/833 (0%)

Query  1    MTFYNHKAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60
            MTFY+H AIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   ILSRFKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120
            ILSRFKRAQG NVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WDREINTTDPSYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180
            WDRE+NTTDP+YYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  181  GYPVVRKPMRQWMLKITAYAERLLADLEEVDWPESIKDMQRNWIGKSTGANvtfkvkdtd  240
            GYPVVRKPMRQWMLKITAYAERLL DLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  241  kdftvfttRPDTLFGATYAVLAPEHALVDSITTAEQAAAVAEYKRQASLKSDLARTDLAK  300
            KDFTVFTTRPDTLFGATYAVLAPEHALVD+ITT++QA AVA+YKRQASLKSDLARTDLAK
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  301  EKTGVWTGAYAINPVNGKEMPIWIADYVLASYGTGAIMAVPAHDERDWAFAKQFNLEIIP  360
            EKTGVWTG+YAINPVNGKEMP+WIADYVLASYGTGAIMAVPAHDERDW FAKQFNL+IIP
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  361  VLEGGNVDEAAYTEDGIHINSGFLDGLDKACAITKMVAWLEETGVGHEKVSYRLRDWLFS  420
            VLEGGNV+EAA+TEDG+HINS+FLDGLDKA AI+KMV WLE  GVG+E+V+YRLRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  421  RQRYWGEPIPIIHWEDGTSTAVPEQDLPLVLPVTKDIRPSGTGESPLANLTDWLEVTRED  480
            RQRYWGEPIPIIHWEDGTSTAVPE +LPLVLPVTKDIRPSGTGESPLAN+TDWLEVTRED
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNDEQLADKDLLKQWLPVDIYIGGAEHAVLHLL  540
            GVKGRRETNTMPQWAGSSWYYLRYIDPHN E+LAD +LLKQWLPVDIY+GGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDHRGALVATDKVDKRDGSFFHMET  600
            YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRD RGALVATDKV+KRDGSFFH+ET
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGARKF  660
            GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEG+RKF
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  661  LDRVYRLITTKEIVAENSGALDKAYHETVKAVTEQIEGMKFNTAIAQLMIFVNAANKEDE  720
            LDRVYRLITTKEI  ENSGALDK Y+ETVKAVTEQ++ MKFNTAIAQLM+FVNAANKED 
Sbjct  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  721  LYVAYAKGFVQLLAPFAPHLGEELWQILTASGQSISYVAWPTHDDSKLVENDVEIVVQIk  780
            L+  YAKGFVQL+APFAPHLGEELWQ LTASG+SISYV+WP+ D+SKLVENDVEIVVQIK
Sbjct  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK  780

Query  781  gkvkaklvvakDLSREELEKVALAHDKIQAEIAGKEVAKVIVVPNKLVNIVVK  833
            GKVKAKLVVAKDLSREEL+ VALA++K+QAEIAGK++ KVI VPNKLVNIV+K
Sbjct  781  GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

95) leuS in NC_017950


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1215 bits (4608),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 745/833 (90%), Positives = 804/833 (97%), Gaps = 0/833 (0%)

Query  1    MSFYNHKEIEPKWQEFWAKNHTFKTGTDAEKPNFYALDMFPYPSGAGLHVGHPEGYTATD  60
            M+FY+H  IEPKWQ FWA NHTFKTGTDA KP+FYALDMFPYPSGAGLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   ILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPADFTAENIANFKRQINALGFSYD  120
            ILSR+KRAQG NVLHPMGWDAFGLPAEQYAMDTGNDPA+FTAENIANFKRQINALGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180
            WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  181  GYPVVRKPMRQWMLKITAYAERLLNDLEEVDWPESIKDMQRNWIGKSTGANvtfkikdtd  240
            GYPVVRKPMRQWMLKITAYAERLL+DLEEVDWPESIKDMQRNWIGKSTGANVTFK+KDTD
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  241  kdftvfttRPDTLFGATYAVLAPEHDLVDSITSSEQAEAVAEYKRQASLKSDLARTDLAK  300
            KDFTVFTTRPDTLFGATYAVLAPEH LVD+IT+S+QAEAVA+YKRQASLKSDLARTDLAK
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  301  DKTGVWTGAYAINPVNGKEIPIWIADYVLASYGTGAIMAVPAHDERDWEFAKQFGLDIIP  360
            +KTGVWTG+YAINPVNGKE+P+WIADYVLASYGTGAIMAVPAHDERDWEFAKQF LDIIP
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  361  VLEGGNVEEAPYTEDGAHINSDFLDGLNKEEAIAKMVAWLEENGVGQEKISYRLRDWLFS  420
            VLEGGNVEEA++TEDG HINSDFLDGL+K  AIAKMV WLE +GVG+E+++YRLRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  421  RQRYWGEPIPIIRWEDGTSTAVPENELPLVLPKTSDIKPSGTGESPLANLTDWLEVVRED  480
            RQRYWGEPIPII+WEDGTSTAVPE+ELPLVLP T DI+PSGTGESPLAN+TDWLEV RED
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNDEKLADEELLKAWLPVDIYIGGAEHAVLHLL  540
            GVKGRRETNTMPQWAGSSWYYLRYIDPHN EKLADEELLK WLPVDIY+GGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  541  YARFWHKFLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFNIET  600
            YARFWHK LYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFF++ET
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  601  GEELEQAPAKMSKSLKNVVNPDDVVEQFGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660
            GEELEQAPAKMSKSLKNVVNPDDVVEQ+GADTLRVYEMFMGPLDASIAWSEEGLEGSRKF
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  661  LDRVYRLLTTKELVAENSGALDKVYNETVKTVTEHIEDLKFNTAIAQLMIFVNAANKEDK  720
            LDRVYRL+TTKE+  ENSGALDKVYNETVK+VTE+++++KFNTAIAQLM+FVNAANKEDK
Sbjct  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  721  LYVEYAKGFVQLIAPFAPHLAEELWQGLANTGQSISYVAWPTYDESKLVESEVEIVVQIK  780
            L+ +YAKGFVQLIAPFAPHL+EELWQ+L+ +G+SISYV+WP+YDESKLVE++VEIVVQIK
Sbjct  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK  780

Query  781  GKVKARLTVAKDLSPAELEKVALADEKVQAEIARQTVVKVISVPNKLVNIVVK  833
            GKVKA+L VAKDLS  EL+ VALA+EKVQAEIA + ++KVI+VPNKLVNIV+K
Sbjct  781  GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

96) leuS in NC_012004


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1215 bits (4607),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 749/833 (90%), Positives = 799/833 (96%), Gaps = 0/833 (0%)

Query  1    MTFYNHKEIEPKWQDFWAKNHTFKTGTDSSKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60
            MTFY+H  IEPKWQ FWA NHTFKTGTD+SKPKFYALDMFPYPSGAGLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   ILSRFKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPADFTAENIANFKRQINSLGFSYD  120
            ILSRFKRAQG NVLHPMGWDAFGLPAEQYAMDTGNDPA+FTAENIANFKRQIN+LGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180
            WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSVGANITFNVKDSE  240
            GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKS GAN+TF+VKD++
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  241  ESFTVFTTRPDTLFGATYAVLAPEHALVDaitteeqaeaiaeYKRQASLKSDLARTDLAK  300
              FTVFTTRPDTLFGATYAVLAPEHALVDAITT +QAEA+A+YKRQASLKSDLARTDLAK
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  301  EKTGVWTGAYAINPVNGKEMPIWIADYVLSSYGTGAIMAVPAHDERDWEFAKQFHLDIIP  360
            EKTGVWTG+YAINPVNGKEMP+WIADYVL+SYGTGAIMAVPAHDERDWEFAKQF+LDIIP
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  361  VLEGGNVQEAAYTEDGLHINSDFLDGLNKEEAIAKTVAWLEEKEVGNEKVSYRLRDWLFS  420
            VLEGGNV+EAA+TEDGLHINSDFLDGL+K  AIAK V WLE   VGNE+V+YRLRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  421  RQRYWGEPIPIIHWEDGTSTAVPEDQLPLILPVTKDIHPSGTGESPLANITDWLEVTRED  480
            RQRYWGEPIPIIHWEDGTSTAVPE +LPL+LPVTKDI+PSGTGESPLAN+TDWLEVTRED
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  481  GVKGRRETNTMPQWAGSSWYYLRYIDPKNDKAIADPDLLKQWLPVDIYVGGAEHAVLHLL  540
            GVKGRRETNTMPQWAGSSWYYLRYIDP N   +AD +LLKQWLPVDIYVGGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDHRGALVATDKVEKREGSYFHIET  600
            YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRD RGALVATDKVEKR+GS+FH+ET
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660
            GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  661  LDRVYRLITTKEMTGDNSGALDKVYHETVKAVTEQIESMKFNTAIAQLMIFVNAANKEDK  720
            LDRVYRLITTKE+T +NSGALDKVY+ETVKAVTEQ++ MKFNTAIAQLM+FVNAANKEDK
Sbjct  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  721  LYKEQAKGFVQLIAPFAPHLGEELWQVLTDSNQSISHVAWPTWDENKLVENDVEIVVQIK  780
            L+ + AKGFVQLIAPFAPHLGEELWQ LT S +SIS V+WP+ DE+KLVENDVEIVVQIK
Sbjct  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK  780

Query  781  GkvkaklvlakDLSKEELEAAALSHEKIQAEIAGKEIVKVIAVPNKLVNIVVK  833
            GKVKAKLV+AKDLS+EEL+  AL++EK+QAEIAGK+I+KVIAVPNKLVNIV+K
Sbjct  781  GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

97) leuS in NC_017576


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1204 bits (4566),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 759/833 (92%), Positives = 809/833 (98%), Gaps = 0/833 (0%)

Query  1    MATYNHKEIEKKWQAYWADNHTFKTGTDADKPNFYALDMFPYPSGAGLHVGHPEGYTATD  60
            M+ Y+H  IE KWQA+WADNHTFKTGTDA KP+FYALDMFPYPSGAGLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   ILSRFKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAQNIANFKRQINSLGFSYD  120
            ILSRFKRAQG NVLHPMGWDAFGLPAEQYAMDTGNDPAEFTA+NIANFKRQIN+LGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180
            WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  181  GYPVVRKPMRQWMLKITAYAerlledledldWPESIKDMQRNWIGKSTGANvtfkikdtd  240
            GYPVVRKPMRQWMLKITAYAERLLEDLE++DWPESIKDMQRNWIGKSTGANVTFK+KDTD
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  241  kdftvfttRPDTLFGATYAVLAPEHPLVEAITTPEQAQAVADYKHQASLKSDLARTDLAK  300
            KDFTVFTTRPDTLFGATYAVLAPEH+LV+AITT++QA+AVADYK+QASLKSDLARTDLAK
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  301  EKTGVWTGSYAINPVNGKEMPIWIADYVLVSYGTGAIMAVPAHDTRDWEFAKQFDLEIIP  360
            EKTGVWTGSYAINPVNGKEMP+WIADYVL SYGTGAIMAVPAHD RDWEFAKQF+L+IIP
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  361  VLEGGNVEEEAYTEDGLHINSGFLDGLDKAQAIDKMVEWLEAEGVGNKKVTYRLRDWLFS  420
            VLEGGNVEE A+TEDGLHINS+FLDGLDKA AI KMVEWLEAEGVGN +VTYRLRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  421  RQRYWGEPIPIIHWEDGTTTAVPEEQLPLVLPVTKDIKPSGTGESPLANLTDWLEVTRED  480
            RQRYWGEPIPIIHWEDGT+TAVPE +LPLVLPVTKDI+PSGTGESPLAN+TDWLEVTRED
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  481  GVKGRRETNTMPQWAGSSWYFLRYIDPHNDEKLADEELLKQWLPVDIYIGGAEHAVLHLL  540
            GVKGRRETNTMPQWAGSSWY+LRYIDPHN EKLADEELLKQWLPVDIY+GGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  541  YARFWHKFLYDLGVVPTKEPFQKLFNQGMILGTSYRDHRGALVATDKVEKRDGSFFHIET  600
            YARFWHK LYDLGVVPTKEPFQKLFNQGMILGTSYRD RGALVATDKVEKRDGSFFH+ET
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  601  GEELEQAPAKMSKSLKNVVNPDDVVEHYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660
            GEELEQAPAKMSKSLKNVVNPDDVVE+YGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  661  LDRIYRLLTTKEIVAENNGNLDKVYNETVKAVTEQLEAMKFNTAIAQLMVFVNAANKEDK  720
            LDR+YRL+TTKEI  EN+G LDKVYNETVKAVTEQ++ MKFNTAIAQLMVFVNAANKEDK
Sbjct  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  721  LFADYAKGFVQLLAPFAPHLSEELWQTLTQSGESISYVAWPTWDEAKLVENDVEIVIQIK  780
            LF+DYAKGFVQL+APFAPHL+EELWQ+LT SGESISYV+WP+ DE+KLVENDVEIV+QIK
Sbjct  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK  780

Query  781  GKVRAKLVVPKDSSREELEKLALANDKIQTEIAGKDIIKVIAVPNKLVNIVVK  833
            GKV+AKLVV+KD SREEL+ +ALAN+K+Q+EIAGKDIIKVIAVPNKLVNIV+K
Sbjct  781  GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

98) leuS in NC_015215


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1204 bits (4566),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 759/833 (92%), Positives = 809/833 (98%), Gaps = 0/833 (0%)

Query  1    MATYNHKEIEKKWQAYWADNHTFKTGTDADKPNFYALDMFPYPSGAGLHVGHPEGYTATD  60
            M+ Y+H  IE KWQA+WADNHTFKTGTDA KP+FYALDMFPYPSGAGLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   ILSRFKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAQNIANFKRQINSLGFSYD  120
            ILSRFKRAQG NVLHPMGWDAFGLPAEQYAMDTGNDPAEFTA+NIANFKRQIN+LGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180
            WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  181  GYPVVRKPMRQWMLKITAYAerlledledldWPESIKDMQRNWIGKSTGANvtfkikdtd  240
            GYPVVRKPMRQWMLKITAYAERLLEDLE++DWPESIKDMQRNWIGKSTGANVTFK+KDTD
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  241  kdftvfttRPDTLFGATYAVLAPEHPLVEAITTPEQAQAVADYKHQASLKSDLARTDLAK  300
            KDFTVFTTRPDTLFGATYAVLAPEH+LV+AITT++QA+AVADYK+QASLKSDLARTDLAK
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  301  EKTGVWTGSYAINPVNGKEMPIWIADYVLVSYGTGAIMAVPAHDTRDWEFAKQFDLEIIP  360
            EKTGVWTGSYAINPVNGKEMP+WIADYVL SYGTGAIMAVPAHD RDWEFAKQF+L+IIP
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  361  VLEGGNVEEEAYTEDGLHINSGFLDGLDKAQAIDKMVEWLEAEGVGNKKVTYRLRDWLFS  420
            VLEGGNVEE A+TEDGLHINS+FLDGLDKA AI KMVEWLEAEGVGN +VTYRLRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  421  RQRYWGEPIPIIHWEDGTTTAVPEEQLPLVLPVTKDIKPSGTGESPLANLTDWLEVTRED  480
            RQRYWGEPIPIIHWEDGT+TAVPE +LPLVLPVTKDI+PSGTGESPLAN+TDWLEVTRED
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  481  GVKGRRETNTMPQWAGSSWYFLRYIDPHNDEKLADEELLKQWLPVDIYIGGAEHAVLHLL  540
            GVKGRRETNTMPQWAGSSWY+LRYIDPHN EKLADEELLKQWLPVDIY+GGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  541  YARFWHKFLYDLGVVPTKEPFQKLFNQGMILGTSYRDHRGALVATDKVEKRDGSFFHIET  600
            YARFWHK LYDLGVVPTKEPFQKLFNQGMILGTSYRD RGALVATDKVEKRDGSFFH+ET
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  601  GEELEQAPAKMSKSLKNVVNPDDVVEHYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660
            GEELEQAPAKMSKSLKNVVNPDDVVE+YGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  661  LDRIYRLLTTKEIVAENNGNLDKVYNETVKAVTEQLEAMKFNTAIAQLMVFVNAANKEDK  720
            LDR+YRL+TTKEI  EN+G LDKVYNETVKAVTEQ++ MKFNTAIAQLMVFVNAANKEDK
Sbjct  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  721  LFADYAKGFVQLLAPFAPHLSEELWQTLTQSGESISYVAWPTWDEAKLVENDVEIVIQIK  780
            LF+DYAKGFVQL+APFAPHL+EELWQ+LT SGESISYV+WP+ DE+KLVENDVEIV+QIK
Sbjct  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK  780

Query  781  GKVRAKLVVPKDSSREELEKLALANDKIQTEIAGKDIIKVIAVPNKLVNIVVK  833
            GKV+AKLVV+KD SREEL+ +ALAN+K+Q+EIAGKDIIKVIAVPNKLVNIV+K
Sbjct  781  GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

99) leuS in NC_013798


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1204 bits (4566),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 760/833 (92%), Positives = 809/833 (98%), Gaps = 0/833 (0%)

Query  1    MATYNHKEIEKKWQAYWADNHTFKTGTDADKPNFYALDMFPYPSGAGLHVGHPEGYTATD  60
            M+ Y+H  IE KWQA+WADNHTFKTGTDA KP+FYALDMFPYPSGAGLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   ILSRFKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAQNIANFKRQINSLGFSYD  120
            ILSRFKRAQG NVLHPMGWDAFGLPAEQYAMDTGNDPAEFTA+NIANFKRQIN+LGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180
            WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  181  GYPVVRKPMRQWMLKITAYAerlledledldWPESIKDMQRNWIGKSTGANvtfkikdtd  240
            GYPVVRKPMRQWMLKITAYAERLLEDLE++DWPESIKDMQRNWIGKSTGANVTFK+KDTD
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  241  kdftvfttRPDTLFGATYAVLAPEHPLVEAITTPEQAQAVADYKHQASLKSDLARTDLAK  300
            KDFTVFTTRPDTLFGATYAVLAPEH+LV+AITT++QA+AVADYK+QASLKSDLARTDLAK
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  301  EKTGVWTGSYAINPVNGKEMPIWIADYVLVSYGTGAIMAVPAHDTRDWEFAKQFDLEIIP  360
            EKTGVWTGSYAINPVNGKEMP+WIADYVL SYGTGAIMAVPAHD RDWEFAKQF+L+IIP
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  361  VLEGGNVEEEAYTEDGLHINSGFLDGLDKAQAIDKMVEWLEAEGVGNKKVTYRLRDWLFS  420
            VLEGGNVEE A+TEDGLHINS+FLDGLDKA AI KMVEWLEAEGVGN +VTYRLRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  421  RQRYWGEPIPIIHWEDGTTTAVPEEQLPLVLPVTKDIKPSGTGESPLANLTDWLEVTRED  480
            RQRYWGEPIPIIHWEDGT+TAVPE +LPLVLPVTKDI+PSGTGESPLAN+TDWLEVTRED
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  481  GVKGRRETNTMPQWAGSSWYFLRYIDPHNDEKLADEELLKQWLPVDIYIGGAEHAVLHLL  540
            GVKGRRETNTMPQWAGSSWY+LRYIDPHN EKLADEELLKQWLPVDIY+GGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  541  YARFWHKFLYDLGVVPTKEPFQKLFNQGMILGTSYRDHRGALVATDKVEKRDGSFFHIET  600
            YARFWHK LYDLGVVPTKEPFQKLFNQGMILGTSYRD RGALVATDKVEKRDGSFFH+ET
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  601  GEELEQAPAKMSKSLKNVVNPDDVVEHYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660
            GEELEQAPAKMSKSLKNVVNPDDVVE+YGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  661  LDRVYRLLTTKEIVAENNGNLDKVYNETVKAVTEQLEAMKFNTAIAQLMVFVNAANKEDK  720
            LDRVYRL+TTKEI  EN+G LDKVYNETVKAVTEQ++ MKFNTAIAQLMVFVNAANKEDK
Sbjct  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  721  LFADYAKGFVQLLAPFAPHLSEELWQTLTQSGESISYVAWPTWDEAKLVENDVEIVIQIK  780
            LF+DYAKGFVQL+APFAPHL+EELWQ+LT SGESISYV+WP+ DE+KLVENDVEIV+QIK
Sbjct  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK  780

Query  781  GKVRAKLVVPKDSSREELEKLALANDKIQTEIAGKDIIKVIAVPNKLVNIVVK  833
            GKV+AKLVV+KD SREEL+ +ALAN+K+Q+EIAGKDIIKVIAVPNKLVNIV+K
Sbjct  781  GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

100) leuS in NC_013928


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1203 bits (4562),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 734/833 (89%), Positives = 803/833 (97%), Gaps = 0/833 (0%)

Query  1    MVYYNHKAIENKWQKFWEDNHTFKTGTASSKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60
            M +Y+H AIE KWQ FW DNHTFKTGT +SKPKFYALDMFPYPSGAGLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   ILSRFKRAQGYSVLHPMGWDAFGLPAEQYAMDTGHDPADFTAQNIATFKRQIKSLGFSYD  120
            ILSRFKRAQG +VLHPMGWDAFGLPAEQYAMDTG+DPA+FTA+NIA FKRQI++LGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WDREINTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180
            WDRE+NTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  181  GYPVVRKPMRQWMLKITAYAerlledledldWPESIKDMQRNWIGKSTGANVTFKVKDTD  240
            GYPVVRKPMRQWMLKITAYAERLLEDLE++DWPESIKDMQRNWIGKSTGANVTFKVKDTD
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  241  EEFTVFTTRPDTLFGATYAVLAPEHDLVDIITTAGQAQAVADYKHQASLKSDLARTDLAK  300
             +FTVFTTRPDTLFGATYAVLAPEH LVD ITT++QA+AVADYK+QASLKSDLARTDLAK
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  301  EKTGIWTGAYAINPVNGKEIPIWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360
            EKTG+WTG+YAINPVNGKE+P+WIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  361  VLEGGNVAEAAYTDDGLHINSGFLNGLDKAAAIDKMVTWLETEGVGNKKVTYRLRDWLFS  420
            VLEGGNV EAA+T+DGLHINS+FL+GLDKA+AI KMV WLE+EGVGN +VTYRLRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  421  RQRYWGEPIPIIHWEDGTSTAlpenelplvlpvTKDIKPSGTGESPLANLTDWLEVSRED  480
            RQRYWGEPIPIIHWEDGTSTA+PE+ELPLVLPVTKDI+PSGTGESPLAN+TDWLEV+RED
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  481  GVKGRRETNTMPQWAGSSWYFLRYIDPHNDQKLADEDLLKQWLPVDVYVGGAEHAVLHLL  540
            GVKGRRETNTMPQWAGSSWY+LRYIDPHN +KLADE+LLKQWLPVD+YVGGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  541  YARFWHKFLYDLGVVPTKEPFQKLFNQGMILGTSYHDHRGALVATDKVEKRDGSFFNIET  600
            YARFWHK LYDLGVVPTKEPFQKLFNQGMILGTSY+D RGALVATDKVEKRDGSFF++ET
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  601  GEELEQAPAKMSKSLKNVVNPDDVIEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660
            GEELEQAPAKMSKSLKNVVNPDDV+EQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  661  LDRVYRLITTKEIAAKNNGHLDKVYNEVVKTVTEHLEAMRFNTAISQLMIFVNAANKEEQ  720
            LDRVYRLITTKEI+  N+G LDKVYNE VK+VTE+++ M+FNTAI+QLM+FVNAANKE++
Sbjct  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  721  LFIDYAKGFIQLLAPFVPHLAEELWQVLTQSGESLSYVTWPSYDESKLVEDEIEIVLQIK  780
            LF DYAKGF+QL+APF PHL+EELWQ LT SGES+SYV WPSYDESKLVE+++EIV+QIK
Sbjct  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK  780

Query  781  GKVRAKVVVSKDSSREDLEKIALANDKIQAEIAGKDIVKVIAVPNKLVNIVIK  833
            GKV+AK+VV+KD SRE+L+ +ALAN+K+QAEIAGKDI+KVIAVPNKLVNIVIK
Sbjct  781  GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

101) leuS in NC_016749


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1202 bits (4559),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 757/833 (91%), Positives = 804/833 (97%), Gaps = 0/833 (0%)

Query  1    MATYNHKEIEKKWQAYWADNHTFKTGTDADKPNFYALDMFPYPSGAGLHVGHPEGYTATD  60
            M+ Y+H  IE KWQA+WADNHTFKTGTDA KP+FYALDMFPYPSGAGLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   ILSRFKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAQNIANFKRQINSLGFSYD  120
            ILSRFKRAQG NVLHPMGWDAFGLPAEQYAMDTGNDPAEFTA+NIANFKRQIN+LGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180
            WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  181  GYPVVRKPMRQWMLKITAYAERlledlddldWPESIKDMQRNWIGKSTGANvtfkvkdtd  240
            GYPVVRKPMRQWMLKITAYAERLLEDL+++DWPESIKDMQRNWIGKSTGANVTFKVKDTD
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  241  kdftvfttRPDTLFGATYAVLAPEHPLVEAITIPEQAQAVADYKHQASLKSDLARTDLAK  300
            KDFTVFTTRPDTLFGATYAVLAPEH+LV+AIT ++QA+AVADYK+QASLKSDLARTDLAK
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  301  EKTGVWTGSYAINPVNGKEMPIWIADYVLVSYGTGAIMAVPAHDTRDWEFAKQFNLEIIP  360
            EKTGVWTGSYAINPVNGKEMP+WIADYVL SYGTGAIMAVPAHD RDWEFAKQFNL+IIP
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  361  VLEGGNVEEEAYTEDGLHINSGFLDGLDKAQAIDKMVEWLEAEGVGNKKVTYRLRDWLFS  420
            VLEGGNVEE A+TEDGLHINS+FLDGLDKA AI KMVEWLEAEGVGN +VTYRLRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  421  RQRYWGEPIPIIHWEDGTTTAVPEDQLPLVLPVTKDIKPSGTGESPLANLTDWLEVTRED  480
            RQRYWGEPIPIIHWEDGT+TAVPE +LPLVLPVTKDI+PSGTGESPLAN+TDWLEVTRED
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  481  GVKGRRETNTMPQWAGSSWYFLRYIDPHNDEKLADEELLKAWLPVDIYIGGAEHAVLHLL  540
            GVKGRRETNTMPQWAGSSWY+LRYIDPHN EKLADEELLK WLPVDIY+GGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  541  YARFWHKFLYDLGVVPTKEPFQKLFNQGMILGTSYRDHRGVLVATDKVEKRDGSFFHIET  600
            YARFWHK LYDLGVVPTKEPFQKLFNQGMILGTSYRD RG LVATDKVEKRDGSFFH+ET
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  601  GEELEQAPAKMSKSLKNVVNPDDVVERYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660
            GEELEQAPAKMSKSLKNVVNPDDVVE+YGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  661  LDRVYRLLTTKEIVAENNGNLDKVYNETVKAVTEQLEAMKFNTAIAQLMVFVNAANKEDK  720
            LDRVYRL+TTKEI  EN+G LDKVYNETVKAVTEQ++ MKFNTAIAQLMVFVNAANKEDK
Sbjct  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  721  LFVDYAKGFVQLLAPFAPHLSEELWQTLTQSGESISYVAWPTWDEAKLVENNVEIVIQIK  780
            LF DYAKGFVQL+APFAPHL+EELWQ+LT SGESISYV+WP+ DE+KLVEN+VEIV+QIK
Sbjct  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK  780

Query  781  GKVRAKLVVPKDSSRQELEKLALANEKIQDEIAGKDIIKVIAVPNKLVNIVVK  833
            GKV+AKLVV+KD SR+EL+ +ALANEK+Q EIAGKDIIKVIAVPNKLVNIV+K
Sbjct  781  GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

102) leuS in NC_018089


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1202 bits (4561),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 736/833 (89%), Positives = 804/833 (97%), Gaps = 0/833 (0%)

Query  1    MVYYNHKAIENKWQKFWEDNHTFKTGTASSKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60
            M +Y+H AIE KWQ FW DNHTFKTGT +SKPKFYALDMFPYPSGAGLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   ILSRFKRAQGYSVLHPMGWDAFGLPAEQYAMDTGHDPADFTAQNIATFKRQIKSLGFSYD  120
            ILSRFKRAQG +VLHPMGWDAFGLPAEQYAMDTG+DPA+FTA+NIA FKRQI++LGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WDREINTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180
            WDRE+NTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  181  GYPVVRKPMRQWMLKITAYAerlledledldWPESIKDMQRNWIGKSTGANVTFKVKDTD  240
            GYPVVRKPMRQWMLKITAYAERLLEDLE++DWPESIKDMQRNWIGKSTGANVTFKVKDTD
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  241  EEFTVFTTRPDTLFGATYAVLAPEHDLVDIITTAGQAQAVADYKHQASLKSDLARTDLAK  300
             +FTVFTTRPDTLFGATYAVLAPEH LVD ITT++QA+AVADYK+QASLKSDLARTDLAK
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  301  EKTGVWTGAYAINPVNGKEIPIWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360
            EKTGVWTG+YAINPVNGKE+P+WIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  361  VLEGGNVAEAAYTDDGLHINSGFLNGLDKAAAIDKMVTWLETEGVGNKKVTYRLRDWLFS  420
            VLEGGNV EAA+T+DGLHINS+FL+GLDKA+AI KMV WLE+EGVGN +VTYRLRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  421  RQRYWGEPIPIIHWEDGTSTAlpenelplvlpvTNDIKPSGTGESPLANLTDWLEVTRED  480
            RQRYWGEPIPIIHWEDGTSTA+PE+ELPLVLPVT+DI+PSGTGESPLAN+TDWLEVTRED
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  481  GVKGRRETNTMPQWAGSSWYFLRYIDPHNDQKLADEDLLKQWLPVDVYVGGAEHAVLHLL  540
            GVKGRRETNTMPQWAGSSWY+LRYIDPHN +KLADE+LLKQWLPVD+YVGGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  541  YARFWHKFLYDLGVVPTKEPFQKLFNQGMILGTSYRDHRGALVATDKVEKRDGSFFNIET  600
            YARFWHK LYDLGVVPTKEPFQKLFNQGMILGTSYRD RGALVATDKVEKRDGSFF++ET
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660
            GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  661  LDRVYRLITTKEIAAKNNGHLDKIYNEVVKTVTEHLEAMRFNTAISQLMIFVNAANKEEQ  720
            LDRVYRLITTKEI+  N+G LDK+YNE VK+VTE+++ M+FNTAI+QLM+FVNAANKE++
Sbjct  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  721  LFLDYAKGFIQLLAPFAPHLAEELWQVLTQSGESLSYVTWPSYDESKLVEDEIEIVLQIK  780
            LF DYAKGF+QL+APFAPHL+EELWQ LT SGES+SYV WPSYDESKLVE+++EIV+QIK
Sbjct  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK  780

Query  781  GKVRAKVVVPKDSSREDLEKIALANDKIQAEIAGKDIVKVIAVPNKLVNIVVK  833
            GKV+AK+VV+KD SRE+L+ +ALAN+K+QAEIAGKDI+KVIAVPNKLVNIV+K
Sbjct  781  GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

103) leuS in NC_017768


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1202 bits (4560),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 736/833 (89%), Positives = 803/833 (97%), Gaps = 0/833 (0%)

Query  1    MVYYNHKAIENKWQKFWEDNHTFKTGTASSKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60
            M +Y+H AIE KWQ FW DNHTFKTGT +SKPKFYALDMFPYPSGAGLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   ILSRFKRAQGYSVLHPMGWDAFGLPAEQYAMDTGHDPADFTAQNIATFKRQIKSLGFSYD  120
            ILSRFKRAQG +VLHPMGWDAFGLPAEQYAMDTG+DPA+FTA+NIA FKRQI++LGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WDREINTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180
            WDRE+NTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  181  GYPVVRKPMRQWMLKITAYAerlledledldWPESIKDMQRNWIGKSTGANVTFKVKDTD  240
            GYPVVRKPMRQWMLKITAYAERLLEDLE++DWPESIKDMQRNWIGKSTGANVTFKVKDTD
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  241  EEFTVFTTRPDTLFGATYAVLAPEHDLVDIITTAGQAQAVADYKHQASLKSDLARTDLAK  300
             +FTVFTTRPDTLFGATYAVLAPEH LVD ITT++QA+AVADYK+QASLKSDLARTDLAK
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  301  EKTGVWTGAYAINPVNGKEIPIWMADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360
            EKTGVWTG+YAINPVNGKE+P+W+ADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  361  VLEGGNVAEAAYTDDGLHINSGFLNGLDKAAAIDKMVTWLETEGVGNKKVTYRLRDWLFS  420
            VLEGGNV EAA+T+DGLHINS+FL+GLDKA+AI KMV WLE+EGVGN +VTYRLRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  421  RQRYWGEPIPIIHWEDGTSTAllenelplvlpvTKDIKPSGTGESPLANLTDWLEVTRED  480
            RQRYWGEPIPIIHWEDGTSTA+ E+ELPLVLPVTKDI+PSGTGESPLAN+TDWLEVTRED
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  481  GVKGRRETNTMPQWAGSSWYFLRYIDPHNDQKLADEDLLKQWLPVDVYVGGAEHAVLHLL  540
            GVKGRRETNTMPQWAGSSWY+LRYIDPHN +KLADE+LLKQWLPVD+YVGGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  541  YARFWHKFLYDLGVVPTKEPFQKLFNQGMILGTSYRDHRGALVATDKVEKRDGSFFNIET  600
            YARFWHK LYDLGVVPTKEPFQKLFNQGMILGTSYRD RGALVATDKVEKRDGSFF++ET
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  601  DEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660
            +EELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  661  LDRVYRLITTKEIAAKNNGHLDKVYNEVVKTVTEHLEAMRFNTAISQLMIFVNAANKEEQ  720
            LDRVYRLITTKEI+  N+G LDKVYNE VK+VTE+++ M+FNTAI+QLM+FVNAANKE++
Sbjct  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  721  LFIDYAKGFIQLLAPFAPHLAEELWQVLTQSGESLSYVTWPSYDESKLVEDEIEIVLQIK  780
            LF DYAKGF+QL+APFAPHL+EELWQ LT SGES+SYV WPSYDESKLVE+++EIV+QIK
Sbjct  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK  780

Query  781  GKVRAKVVVSKDSSREDLEKIALANDKIQAEIAGKDIVKVIAVPNKLVNIVIK  833
            GKV+AK+VV+KD SRE+L+ +ALAN+K+QAEIAGKDI+KVIAVPNKLVNIVIK
Sbjct  781  GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

104) syl in NC_004350


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1201 bits (4557),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 737/833 (89%), Positives = 805/833 (97%), Gaps = 0/833 (0%)

Query  1    MVYYNHKAIENKWQKFWEDNHTFKTGTASSKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60
            M +Y+H AIE KWQ FW DNHTFKTGT +SKPKFYALDMFPYPSGAGLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   ILSRFKRAQGYNVLHPMGWDAFGLPAEQYAMDTGHDPADFTAQNIATFKRQIKSLGFSYD  120
            ILSRFKRAQG NVLHPMGWDAFGLPAEQYAMDTG+DPA+FTA+NIA FKRQI++LGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WDREINTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180
            WDRE+NTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  181  GYPVVRKPMRQWMLKITAYAerlledledldWPESIKDMQRNWIGKSTGANVTFKVKDTD  240
            GYPVVRKPMRQWMLKITAYAERLLEDLE++DWPESIKDMQRNWIGKSTGANVTFKVKDTD
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  241  EEFTVFTTRPDTLFGATYAVLAPEHDLVDIITTAGQAQAVADYKHQASLKSDLARTDLAK  300
             +FTVFTTRPDTLFGATYAVLAPEH LVD ITT++QA+AVADYK+QASLKSDLARTDLAK
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  301  EKTGVWTGAYAINPVNGKEIPIWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360
            EKTGVWTG+YAINPVNGKE+P+WIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  361  VLEGGNVAEAAYTDDGLHINSGFLNGLDKAAAIDKMVTWLETEGVGNKKVTYRLRDWLFS  420
            VLEGGNV EAA+T+DGLHINS+FL+GLDKA+AI KMV WLE+EGVGN +VTYRLRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  421  RQRYWGEPIPIIHWEDGTSTAlpenelplvlpvTKDIKPSGTGESPLANLTDWLEVTRED  480
            RQRYWGEPIPIIHWEDGTSTA+PE+ELPLVLPVTKDI+PSGTGESPLAN+TDWLEVTRED
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  481  GVKGRRETNTMPQWAGSSWYFLRYIDPHNDQKLADEDLLKQWLPVDVYVGGAEHAVLHLL  540
            GVKGRRETNTMPQWAGSSWY+LRYIDPHN +KLADE+LLKQWLPVD+YVGGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  541  YARFWHKFLYDLGVVPTKEPFQKLFNQGMILGTSYRDHRGALVATDKVEKRDGSFFNIET  600
            YARFWHK LYDLGVVPTKEPFQKLFNQGMILGTSYRD RGALVATDKVEKRDGSFF++ET
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  601  DEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660
            +EELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  661  LDRVYRLITTKEIAAKNNGHLDKVYNEVVKTVTEHLEAMRFNTAISQLMIFVNAANKEEQ  720
            LDRVYRLITTKEI+  N+G LDKVYNE VK+VTE+++ M+FNTAI+QLM+FVNAANKE++
Sbjct  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  721  LFLDYAKGFIQLLAPFAPHLAEELWQFLTQSGQSITYVAWPSYDESKLVEDEIEIVLQIK  780
            LF DYAKGF+QL+APFAPHL+EELWQ LT SG+SI+YV+WPSYDESKLVE+++EIV+QIK
Sbjct  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK  780

Query  781  GKVRAKVVVSKDSSREDLEKIALANDKIQAEVAGKDIVKVIAVPNKLVNIVIK  833
            GKV+AK+VV+KD SRE+L+ +ALAN+K+QAE+AGKDI+KVIAVPNKLVNIVIK
Sbjct  781  GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

105) leuS in NC_015600


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1197 bits (4541),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 755/833 (91%), Positives = 805/833 (97%), Gaps = 0/833 (0%)

Query  1    MATYNHKEIEKKWQAYWAVNHTFKTGTDADKPNFYALDMFPYPSGAGLHVGHPEGYTATD  60
            M+ Y+H  IE KWQA+WA NHTFKTGTDA KP+FYALDMFPYPSGAGLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   ILSRFKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAKNIANFKRQINSLGFSYD  120
            ILSRFKRAQG NVLHPMGWDAFGLPAEQYAMDTGNDPAEFTA NIANFKRQIN+LGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180
            WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  181  GYPVVRKPMRQWMLKITAYAerlledledldWPESIKDMQRNWIGKSTGANvtfkikdtd  240
            GYPVVRKPMRQWMLKITAYAERLLEDLE++DWPESIKDMQRNWIGKSTGANVTFK+KDTD
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  241  kdftvfttRPDTLFGATYAVLAPEHPLVEAITTPEQAQAVADYQHQASLKSDLARTDLAK  300
            KDFTVFTTRPDTLFGATYAVLAPEH+LV+AITT++QA+AVADY++QASLKSDLARTDLAK
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  301  EKTGVWTGSYAINPVTGKEMPIWIADYVLVSYGTGAIMAVPAHDTRDWEFAKQFDLEIIP  360
            EKTGVWTGSYAINPV GKEMP+WIADYVL SYGTGAIMAVPAHD RDWEFAKQF+L+IIP
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  361  VLEGGNVEEEAYTEDGLHVNSGFLDGLDKAQAIDKMVEWLEAEGVGNKKVTYRLRDWLFS  420
            VLEGGNVEE A+TEDGLH+NS+FLDGLDKA AI KMVEWLEAEGVGN +VTYRLRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  421  RQRYWGEPIPIIHWEDGTTTAVPEEQLPLVLPVTKDIKPSGTGESPLANLTDWLEVTRED  480
            RQRYWGEPIPIIHWEDGT+TAVPE +LPLVLPVTKDI+PSGTGESPLAN+TDWLEVTRED
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  481  GVKGRRETNTMPQWAGSSWYFLRYIDPHNDEKLADEELLKAWLPVDIYIGGAEHAVLHLL  540
            GVKGRRETNTMPQWAGSSWY+LRYIDPHN EKLADEELLK WLPVDIY+GGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  541  YARFWHKFLYDLGVVPTKEPFQKLFNQGMILGTSYRDHRGALVATDKVEKRDGSFFHIET  600
            YARFWHK LYDLGVVPTKEPFQKLFNQGMILGTSYRD RGALVATDKVEKRDGSFFH+ET
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  601  GEELEQAPAKMSKSLKNVVNPDDVVEHYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660
            GEELEQAPAKMSKSLKNVVNPDDVVE+YGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  661  LDRVYRLLTTKEIVAENNGNLDKVYNETVKAVTEQLEAMKFNTAIAQLMVFVNAANKEDK  720
            LDRVYRL+TTKEI  EN+G LDKVYNETVKAVTEQ++ MKFNTAIAQLMVFVNAANKEDK
Sbjct  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  721  LFADYAKGFVQLLAPFAPHLSEELWQTLTQSGESISYVAWPTWDEAKLVENDVEIVIQIK  780
            LF+DYAKGFVQL+APFAPHL+EELWQ+LT SGESISYV+WP+ DE+KLVENDVEIV+QIK
Sbjct  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK  780

Query  781  GKVRAKLVVPKDSSREELEKLALANDKIQTEIAGKDIIKVIAVPNKLVNIVVK  833
            GKV+AKLVV+KD SREEL+ +ALAN+K+Q+EIAGKDIIKVIAVPNKLVNIV+K
Sbjct  781  GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

106) leuS in NC_021213


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1193 bits (4525),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 732/815 (90%), Positives = 787/815 (97%), Gaps = 0/815 (0%)

Query  1    MSFYNHKEIEPKWQEFWAKNHTFKTGTDAEKPNFYALDMFPYPSGAGLHVGHPEGYTATD  60
            M+FY+H  IEPKWQ FWA NHTFKTGTDA KP+FYALDMFPYPSGAGLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   ILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPADFTAENIANFKRQINALGFSYD  120
            ILSR+KRAQG NVLHPMGWDAFGLPAEQYAMDTGNDPA+FTAENIANFKRQINALGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180
            WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  181  GYPVVRKPMRQWMLKITAYAERLLNDLEEVDWPESIKDMQRNWIGKSTGANvtfkikdtd  240
            GYPVVRKPMRQWMLKITAYAERLL+DLEEVDWPESIKDMQRNWIGKSTGANVTFK+KDTD
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  241  kdftvfttRPDTLFGATYAVLAPEHDLVDSITSSEQEEAVAEYKRQASLKSDLARTDLAK  300
            KDFTVFTTRPDTLFGATYAVLAPEH LVD+IT+S+Q EAVA+YKRQASLKSDLARTDLAK
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  301  DKTGVWTGAYAINPVNGKEIPIWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDVIP  360
            +KTGVWTG+YAINPVNGKE+P+WIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLD+IP
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  361  VLEGGNVEEAPYTEDGAHINSDFLDGLNKEEAIAKMVAWLEETGVGQEKISYRLRDWLFS  420
            VLEGGNVEEA++TEDG HINSDFLDGL+K  AIAKMV WLE  GVG+E+++YRLRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  421  RQRYWGEPIPIIHWEDGTSTAVPENELPLVLPKTSDIKPSGTGESPLANLTDWLEVVRED  480
            RQRYWGEPIPIIHWEDGTSTAVPE+ELPLVLP T DI+PSGTGESPLAN+TDWLEV RED
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNDEKLADEELLKAWLPVDIYIGGAEHAVLHLL  540
            GVKGRRETNTMPQWAGSSWYYLRYIDPHN EKLADEELLK WLPVDIY+GGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  541  YARFWHKFLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFNIET  600
            YARFWHK LYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFF++ET
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  601  GEELEQAPAKMSKSLKNVVNPDDVVEQFGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660
            GEELEQAPAKMSKSLKNVVNPDDVVEQ+GADTLRVYEMFMGPLDASIAWSEEGLEGSRKF
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  661  LDRVYRLLTTKELVAENSGALDKVYNETVKTVTEHIEDLKFNTAIAQLMIFVNAANKEDK  720
            LDRVYRL+TTKE+  ENSGALDKVYNETVK+VTE+++++KFNTAIAQLM+FVNAANKEDK
Sbjct  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  721  LYVEYAKGFVQLIAPFAPHLAEELWQGLANTGQSISYVAWPTYDESKLVESEVEIVVQIK  780
            L+ +YAKGFVQLIAPFAPHL+EELWQ+L+ +G+SISYV+WP+YDESKLVE++VEIVVQIK
Sbjct  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK  780

Query  781  GKVKARLTVAKDLAPAELEKVALADEKVQAEIAGQ  815
            GKVKA+L VAKDL+  EL+ VALA+EKVQAEIAG+
Sbjct  781  GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGK  815

107) leuS in NC_022237


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1187 bits (4504),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 756/833 (91%), Positives = 805/833 (97%), Gaps = 0/833 (0%)

Query  1    MTFYNHKSIEKKWQKYWAENHTFKTGTAASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60
            MTFY+H +IE KWQ +WA+NHTFKTGT ASKPKFYALDMFPYPSGAGLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   ILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAKNIANFKRQINSLGFSYD  120
            ILSR+KRAQG NVLHPMGWDAFGLPAEQYAMDTGNDPAEFTA NIANFKRQIN+LGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WDREINTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180
            WDRE+NTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  181  GYPVVRKPMRQWMLKITAYAERlledlddldWPESIKDMQRNWIGKSTGANvtfkvkdtd  240
            GYPVVRKPMRQWMLKITAYAERLLEDL+++DWPESIKDMQRNWIGKSTGANVTFKVKDTD
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  241  kdftvfttRPDTLFGATYAVLAPEHALVDAITSPEQAQAVTDYKHQASLKSDLARTDLAK  300
            KDFTVFTTRPDTLFGATYAVLAPEHALVDAIT+++QA+AV+DYK+QASLKSDLARTDLAK
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  301  EKTGVWTGSYAINPVNGKEIPIWIADYVLASYGTGAIMAVPAHDDRDWEFAKQFDLEIIP  360
            EKTGVWTGSYAINPVNGKE+P+WIADYVLASYGTGAIMAVPAHD+RDWEFAKQF+L+IIP
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  361  VLEGGNVEEAAYTEDGLHINSSFLDGLDKAQAIDKMVAWLEAEGVGNKKVTYRLRDWLFS  420
            VLEGGNVEEAA+TEDGLHINS FLDGLDKA AI KMV WLEAEGVGN +VTYRLRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  421  RQRYWGEPIPIIHWEDGTTTAVPEDQLPLVLPVTKDIKPSGTGESPLANLTDWLEVTRED  480
            RQRYWGEPIPIIHWEDGT+TAVPE +LPLVLPVTKDI+PSGTGESPLAN+TDWLEVTRED
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKAWLPVDIYIGGAEHAVLHLL  540
            GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLK WLPVDIY+GGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  541  YARFWHKFLYDLGVVPTKEPFQKLFNQGMILGTSYRDHRGALVVTDKVEKRDGSFFNIET  600
            YARFWHK LYDLGVVPTKEPFQKLFNQGMILGTSYRD RGALV TDKVEKRDGSFF++ET
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660
            GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  661  LDRVYRLLITKEIVAENNGNLDKVYNETVKAVTEQLEAMKFNTAIAQLMVFINAANKEDK  720
            LDRVYRL+ TKEI  EN+G LDKVYNETVKAVTEQ++ MKFNTAIAQLMVF+NAANKEDK
Sbjct  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  721  LFADYAKGFVQLLAPFAPHLSEELWQTLTQSGESISYVLWPTWDEAKLVENDVEIVVQIK  780
            LF+DYAKGFVQL+APFAPHL+EELWQ+LT SGESISYV WP+ DE+KLVENDVEIVVQIK
Sbjct  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK  780

Query  781  GKVRAKLVVPKDSSReeleklalanekIQVEIAGKQVIKVIVVPNKLVNIVVK  833
            GKV+AKLVV+KD SREEL+ +ALANEK+Q EIAGK++IKVI VPNKLVNIV+K
Sbjct  781  GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

108) leuS in NC_022244


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1173 bits (4449),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 739/813 (91%), Positives = 789/813 (98%), Gaps = 0/813 (0%)

Query  1    MTFYNHKSIEKKWQNYWAENHTFKTGTDADKPNFYALDMFPYPSGAGLHVGHPEGYTATD  60
            MTFY+H +IE KWQ +WA+NHTFKTGTDA KP+FYALDMFPYPSGAGLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   ILSRFKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120
            ILSRFKRAQG NVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180
            WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  181  GYPVVRKPMRQWMLKITAYAerlledledldWPESIKDMQRNWIGKSTGANvtfkikdtd  240
            GYPVVRKPMRQWMLKITAYAERLLEDLE++DWPESIKDMQRNWIGKSTGANVTFK+KDTD
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  241  kdftvfttRPDTLFGATYAVLAPEHPLVDVITTPEQAQAVADYKHQASLKSDLARTDLAK  300
            KDFTVFTTRPDTLFGATYAVLAPEH+LVD ITT++QA+AVADYK+QASLKSDLARTDLAK
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  301  EKTGVWTGSYAINPVNGKEIPIWIADYVLVSYGTGAIMAVPAHDTRDWEFAKQFDLEIIP  360
            EKTGVWTGSYAINPVNGKE+P+WIADYVL SYGTGAIMAVPAHD RDWEFAKQF+L+IIP
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  361  VLEGGNVEEGAFTEDGLHINSGFLDGLDKAQAIDKMVDWLEAEGVGNKKVTYRLRDWLFS  420
            VLEGGNVEE+AFTEDGLHINS+FLDGLDKA AI KMV+WLEAEGVGN +VTYRLRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  421  RQRYWGEPIPIIHWEDGTTTAVPEEQLPLVLPVTKDIKPSGTGESPLANLTDWLEVTRED  480
            RQRYWGEPIPIIHWEDGT+TAVPE +LPLVLPVTKDI+PSGTGESPLAN+TDWLEVTRED
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  481  GMKGRRETNTMPQWAGSSWYYLRYIDPHNDEKLADEELLKAWLPVDIYIGGAEHAVLHLL  540
            G+KGRRETNTMPQWAGSSWYYLRYIDPHN EKLADEELLK WLPVDIY+GGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  541  YARFWHKFLYDLGAVPTKEPFQKLFNQGMILGTSYRDHRGALVATDKVEKRDGSFFHIET  600
            YARFWHK LYDLG VPTKEPFQKLFNQGMILGTSYRD RGALVATDKVEKRDGSFFH+ET
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  601  GEELEQAPAKMSKSLKNVVNPDDVVERYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660
            GEELEQAPAKMSKSLKNVVNPDDVVE+YGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  661  LDRVYRLLTTKEIVAENSGALDKVYNQTVKAVTEQLEELKFNTAIAQLMVFVNAANKEDK  720
            LDRVYRL+TTKEI  ENSGALDKVYN+TVKAVTEQ++++KFNTAIAQLMVFVNAANKEDK
Sbjct  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  721  LFVGYAKGFVQLLAPFAPHLSEELWQTLTQSGESISYVPWPTWDEAKLVEDEVEIVVQIK  780
            LF +YAKGFVQL+APFAPHL+EELWQ+LT SGESISYVPWP+ DE+KLVE++VEIVVQIK
Sbjct  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK  780

Query  781  GKVRAKLVIAKDSSREELEKLALTNEKIQSEIA  813
            GKV+AKLV+AKD SREEL+ +AL+NEK+Q+EIA
Sbjct  781  GKVKAKLVVAKDLSREELQEVALANEKVQAEIA  813

109) leuS in NC_022238


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1171 bits (4442),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 738/810 (92%), Positives = 786/810 (98%), Gaps = 0/810 (0%)

Query  1    MTFYNHKSIEKKWQNYWAENHTFKTGTDADKPNFYALDMFPYPSGAGLHVGHPEGYTATD  60
            MTFY+H +IE KWQ +WA+NHTFKTGTDA KP+FYALDMFPYPSGAGLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   ILSRFKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120
            ILSRFKRAQG NVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WDREVNTTDPNYYKWTQWICTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180
            WDREVNTTDPNYYKWTQWI TKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  181  GYPVVRKPMRQWMLKITAYAerlledledldWPESIKDMQRNWIGKSTGANvtfkikdtd  240
            GYPVVRKPMRQWMLKITAYAERLLEDLE++DWPESIKDMQRNWIGKSTGANVTFK+KDTD
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  241  kdftvfttRPDTLFGATYAVLAPEHPLVDVITTPEQAQAVADYKHQASLKSDLARTDLAK  300
            KDFTVFTTRPDTLFGATYAVLAPEH+LVD ITT++QA+AVADYK+QASLKSDLARTDLAK
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  301  EKTGVWTGSYAINPVNGKEIPIWIADYVLVSYGTGAIMAVPAHDERDWEFAKQFGLEIVP  360
            EKTGVWTGSYAINPVNGKE+P+WIADYVL SYGTGAIMAVPAHDERDWEFAKQF L+I+P
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  361  VLEGGNVEEGAFTEDGLHINSGFLDGLDKAQAIDKMVDWLEAEGVGNKKVTYRLRDWLFS  420
            VLEGGNVEE+AFTEDGLHINS+FLDGLDKA AI KMV+WLEAEGVGN +VTYRLRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  421  RQRYWGEPIPIIHWEDGTTTAVPEEQLPLVLPVTKDIKPSGTGESPLANLTDWLEVTRED  480
            RQRYWGEPIPIIHWEDGT+TAVPE +LPLVLPVTKDI+PSGTGESPLAN+TDWLEVTRED
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKAWLPVDIYIGGAEHAVLHLL  540
            GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLK WLPVDIY+GGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDHRGALVATDKVEKRDGSFFNIET  600
            YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRD RGALVATDKVEKRDGSFF++ET
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660
            GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  661  LDRVYRLLTTKEIVAENNGNLDKVYNETVKSVTEQLEAMKFNTAIAQLMVFINAANKEDK  720
            LDRVYRL+TTKEI  EN+G LDKVYNETVK+VTEQ++ MKFNTAIAQLMVF+NAANKEDK
Sbjct  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  721  LFADYAKGFIQLLAPFAPHLSEELWQTLTQSGESISYVLWPTWDEAKLVENDVEIVVQIK  780
            LF+DYAKGF+QL+APFAPHL+EELWQ+LT SGESISYV WP+ DE+KLVENDVEIVVQIK
Sbjct  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK  780

Query  781  GKVRAKLVVPKDSSREELEKLALSNEKIQS  810
            GKV+AKLVV+KD SREEL+ +AL+NEK+Q+
Sbjct  781  GKVKAKLVVAKDLSREELQEVALANEKVQA  810

110) leuS in NC_022236


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1171 bits (4442),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 738/810 (92%), Positives = 786/810 (98%), Gaps = 0/810 (0%)

Query  1    MTFYNHKSIEKKWQNYWAENHTFKTGTDADKPNFYALDMFPYPSGAGLHVGHPEGYTATD  60
            MTFY+H +IE KWQ +WA+NHTFKTGTDA KP+FYALDMFPYPSGAGLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   ILSRFKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120
            ILSRFKRAQG NVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WDREVNTTDPNYYKWTQWICTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180
            WDREVNTTDPNYYKWTQWI TKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  181  GYPVVRKPMRQWMLKITAYAerlledledldWPESIKDMQRNWIGKSTGANvtfkikdtd  240
            GYPVVRKPMRQWMLKITAYAERLLEDLE++DWPESIKDMQRNWIGKSTGANVTFK+KDTD
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  241  kdftvfttRPDTLFGATYAVLAPEHPLVDVITTPEQAQAVADYKHQASLKSDLARTDLAK  300
            KDFTVFTTRPDTLFGATYAVLAPEH+LVD ITT++QA+AVADYK+QASLKSDLARTDLAK
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  301  EKTGVWTGSYAINPVNGKEIPIWIADYVLVSYGTGAIMAVPAHDERDWEFAKQFGLEIVP  360
            EKTGVWTGSYAINPVNGKE+P+WIADYVL SYGTGAIMAVPAHDERDWEFAKQF L+I+P
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  361  VLEGGNVEEGAFTEDGLHINSGFLDGLDKAQAIDKMVDWLEAEGVGNKKVTYRLRDWLFS  420
            VLEGGNVEE+AFTEDGLHINS+FLDGLDKA AI KMV+WLEAEGVGN +VTYRLRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  421  RQRYWGEPIPIIHWEDGTTTAVPEEQLPLVLPVTKDIKPSGTGESPLANLTDWLEVTRED  480
            RQRYWGEPIPIIHWEDGT+TAVPE +LPLVLPVTKDI+PSGTGESPLAN+TDWLEVTRED
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKAWLPVDIYIGGAEHAVLHLL  540
            GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLK WLPVDIY+GGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDHRGALVATDKVEKRDGSFFNIET  600
            YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRD RGALVATDKVEKRDGSFF++ET
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660
            GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  661  LDRVYRLLTTKEIVAENNGNLDKVYNETVKSVTEQLEAMKFNTAIAQLMVFINAANKEDK  720
            LDRVYRL+TTKEI  EN+G LDKVYNETVK+VTEQ++ MKFNTAIAQLMVF+NAANKEDK
Sbjct  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  721  LFADYAKGFIQLLAPFAPHLSEELWQTLTQSGESISYVLWPTWDEAKLVENDVEIVVQIK  780
            LF+DYAKGF+QL+APFAPHL+EELWQ+LT SGESISYV WP+ DE+KLVENDVEIVVQIK
Sbjct  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK  780

Query  781  GKVRAKLVVPKDSSREELEKLALSNEKIQS  810
            GKV+AKLVV+KD SREEL+ +AL+NEK+Q+
Sbjct  781  GKVKAKLVVAKDLSREELQEVALANEKVQA  810

111) leuS in NC_022245


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1171 bits (4442),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 738/810 (92%), Positives = 786/810 (98%), Gaps = 0/810 (0%)

Query  1    MTFYNHKSIEKKWQNYWAENHTFKTGTDADKPNFYALDMFPYPSGAGLHVGHPEGYTATD  60
            MTFY+H +IE KWQ +WA+NHTFKTGTDA KP+FYALDMFPYPSGAGLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   ILSRFKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120
            ILSRFKRAQG NVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WDREVNTTDPNYYKWTQWICTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180
            WDREVNTTDPNYYKWTQWI TKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  181  GYPVVRKPMRQWMLKITAYAerlledledldWPESIKDMQRNWIGKSTGANvtfkikdtd  240
            GYPVVRKPMRQWMLKITAYAERLLEDLE++DWPESIKDMQRNWIGKSTGANVTFK+KDTD
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  241  kdftvfttRPDTLFGATYAVLAPEHPLVDVITTPEQAQAVADYKHQASLKSDLARTDLAK  300
            KDFTVFTTRPDTLFGATYAVLAPEH+LVD ITT++QA+AVADYK+QASLKSDLARTDLAK
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  301  EKTGVWTGSYAINPVNGKEIPIWIADYVLVSYGTGAIMAVPAHDERDWEFAKQFGLEIVP  360
            EKTGVWTGSYAINPVNGKE+P+WIADYVL SYGTGAIMAVPAHDERDWEFAKQF L+I+P
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  361  VLEGGNVEEGAFTEDGLHINSGFLDGLDKAQAIDKMVDWLEAEGVGNKKVTYRLRDWLFS  420
            VLEGGNVEE+AFTEDGLHINS+FLDGLDKA AI KMV+WLEAEGVGN +VTYRLRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  421  RQRYWGEPIPIIHWEDGTTTAVPEEQLPLVLPVTKDIKPSGTGESPLANLTDWLEVTRED  480
            RQRYWGEPIPIIHWEDGT+TAVPE +LPLVLPVTKDI+PSGTGESPLAN+TDWLEVTRED
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKAWLPVDIYIGGAEHAVLHLL  540
            GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLK WLPVDIY+GGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDHRGALVATDKVEKRDGSFFNIET  600
            YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRD RGALVATDKVEKRDGSFF++ET
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660
            GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  661  LDRVYRLLTTKEIVAENNGNLDKVYNETVKSVTEQLEAMKFNTAIAQLMVFINAANKEDK  720
            LDRVYRL+TTKEI  EN+G LDKVYNETVK+VTEQ++ MKFNTAIAQLMVF+NAANKEDK
Sbjct  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  721  LFADYAKGFIQLLAPFAPHLSEELWQTLTQSGESISYVLWPTWDEAKLVENDVEIVVQIK  780
            LF+DYAKGF+QL+APFAPHL+EELWQ+LT SGESISYV WP+ DE+KLVENDVEIVVQIK
Sbjct  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK  780

Query  781  GKVRAKLVVPKDSSREELEKLALSNEKIQS  810
            GKV+AKLVV+KD SREEL+ +AL+NEK+Q+
Sbjct  781  GKVKAKLVVAKDLSREELQEVALANEKVQA  810

112) leuS in NC_022239


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1166 bits (4422),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 742/813 (92%), Positives = 791/813 (98%), Gaps = 0/813 (0%)

Query  1    MTFYNHKSIEKKWQNYWVENHTFKTGTDADKPNFYALDMFPYPSGAGLHVGHPEGYTATD  60
            MTFY+H +IE KWQ +W +NHTFKTGTDA KP+FYALDMFPYPSGAGLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   ILSRFKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINSLGFSYD  120
            ILSRFKRAQG NVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQIN+LGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180
            WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  181  GYPVVRKPMRQWMLKITAYAERlledlddldWPESIKDMQRNWIGKSTGANvtfkikdtd  240
            GYPVVRKPMRQWMLKITAYAERLLEDL+++DWPESIKDMQRNWIGKSTGANVTFK+KDTD
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  241  kdftvfttRPDTLFGATYAVLAPEHPLVDVITTPEQAQAVADYKHQASLKSDLARTDLAK  300
            KDFTVFTTRPDTLFGATYAVLAPEH+LVD ITT++QA+AVADYK+QASLKSDLARTDLAK
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  301  EKTGVWTGSYAINPVNGKEIPIWIADYVLVSYGTGAIMAVPAHDERDWEFAKQFGLEIVP  360
            EKTGVWTGSYAINPVNGKE+P+WIADYVL SYGTGAIMAVPAHDERDWEFAKQF L+I+P
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  361  VLEGGNVEEGAFTEDGLHINSGFLDGLDKAQAIDKMVDWLEAEGVGNKKVTYRLRDWLFS  420
            VLEGGNVEE+AFTEDGLHINS+FLDGLDKA AI KMV+WLEAEGVGN +VTYRLRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  421  RQRYWGEPIPIIHWEDGTTTAVPEEQLPLVLPVTKDIKPSGTGESPLANLTDWLEVTRED  480
            RQRYWGEPIPIIHWEDGT+TAVPE +LPLVLPVTKDI+PSGTGESPLAN+TDWLEVTRED
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKAWLPVDIYIGGAEHAVLHLL  540
            GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLK WLPVDIY+GGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDHRGALVATDKVEKRDGSFFNIET  600
            YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRD RGALVATDKVEKRDGSFF++ET
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660
            GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  661  LDRVYRLLTTKEIVAENSGALDKVYNQTVKAVTEQLEELKFNTAIAQLMVFVNAANKEDK  720
            LDRVYRL+TTKEI  ENSGALDKVYN+TVKAVTEQ++++KFNTAIAQLMVFVNAANKEDK
Sbjct  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  721  LFVGYAKGFVQLLAPFAPHLSEELWQTLTQSGESISYVPWPTWDEAKLVEDEVEIVVQIK  780
            LF +YAKGFVQL+APFAPHL+EELWQ+LT SGESISYVPWP+ DE+KLVE++VEIVVQIK
Sbjct  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK  780

Query  781  GKVRAKLVVAKDSSReeleklalanekIQSEIA  813
            GKV+AKLVVAKD SREEL+ +ALANEK+Q+EIA
Sbjct  781  GKVKAKLVVAKDLSREELQEVALANEKVQAEIA  813

113) leuS in NC_018073


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1160 bits (4398),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 737/811 (91%), Positives = 787/811 (98%), Gaps = 0/811 (0%)

Query  1    MTFYNHKSIEKKWQKYWAENHTFKTGTAASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60
            MTFY+H +IE KWQ +WA+NHTFKTGT ASKPKFYALDMFPYPSGAGLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   ILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAKNIANFKRQINSLGFSYD  120
            ILSR+KRAQG NVLHPMGWDAFGLPAEQYAMDTGNDPAEFTA NIANFKRQIN+LGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WDREINTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180
            WDRE+NTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  181  GYSVVRKPMRQWMLKITAYAERlledlddldWPESIKDMQRNWIGKSTGANvtfkvkdtd  240
            GY+VVRKPMRQWMLKITAYAERLLEDL+++DWPESIKDMQRNWIGKSTGANVTFKVKDTD
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  241  kdftvfttRPDTLFGATYAVLAPEHALVDAITSPEQaqavaaykraaSLKSDLARTDLAK  300
            KDFTVFTTRPDTLFGATYAVLAPEHALVDAIT+++QA+AVA YKR ASLKSDLARTDLAK
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  301  EKTGVWTGSYAINPVNGKEIPIWIADYVLASYGTGAIMAVPAHDDRDWEFAKQFDLEIIP  360
            EKTGVWTGSYAINPVNGKE+P+WIADYVLASYGTGAIMAVPAHD+RDWEFAKQF+L+IIP
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  361  VLEGGNVEEAAYTEDGLHINSGFLDGLDKAQAIDKMVAWLEAEGVGNKKVTYRLRDWLFS  420
            VLEGGNVEEAA+TEDGLHINS+FLDGLDKA AI KMV WLEAEGVGN +VTYRLRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  421  RQRYWGEPIPIIHWEDGTTTAVPEDQLPLVLPVTKDIKPSGTGESPLANLTDWLEVTRED  480
            RQRYWGEPIPIIHWEDGT+TAVPE +LPLVLPVTKDI+PSGTGESPLAN+TDWLEVTRED
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKAWLPVDIYIGGAEHAVLHLL  540
            GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLK WLPVDIY+GGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDHRGALVATDKVEKRDGSFFNIET  600
            YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRD RGALVATDKVEKRDGSFF++ET
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660
            GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  661  LDRVYRLLTTKEIVAENNGNLDKVYNETVKAVTEQLEAMKFNTAIAQLMVFINAANKEDK  720
            LDRVYRL+TTKEI  EN+G LDKVYNETVKAVTEQ++ MKFNTAIAQLMVF+NAANKEDK
Sbjct  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  721  LFADYAKGFIQLLAPFAPHLSEELWQTLTQSGESISYVLWPTWDEAKLVENDVEIVVQIK  780
            LF+DYAKGF+QL+APFAPHL+EELWQ+LT SGESISYV WP+ DE+KLVENDVEIVVQIK
Sbjct  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK  780

Query  781  GKVRAKLVVPKDSSREDLEKLALANDKIQSE  811
            GKV+AKLVV+KD SRE+L+ +ALAN+K+Q+E
Sbjct  781  GKVKAKLVVAKDLSREELQEVALANEKVQAE  811

114) leuS in NC_022246


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1157 bits (4389),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 736/810 (91%), Positives = 784/810 (97%), Gaps = 0/810 (0%)

Query  1    MTFYNHKSIEKKWQKYWAENHTFKTGTVVSKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60
            MTFY+H +IE KWQ +WA+NHTFKTGT  SKPKFYALDMFPYPSGAGLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   ILSRFKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAKNIANFKRQINSLGFSYD  120
            ILSRFKRAQG NVLHPMGWDAFGLPAEQYAMDTGNDPAEFTA NIANFKRQIN+LGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WDREINTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180
            WDRE+NTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  181  GYPVVRKPMRQWMLKITAYAERlledlddldWPESIKDMQRNWIGKSTGANvtfkvkdtd  240
            GYPVVRKPMRQWMLKITAYAERLLEDL+++DWPESIKDMQRNWIGKSTGANVTFKVKDTD
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  241  kdftvfttRPDTLFGATYAVLAPEHALVDAITSPEQaqavaaykraaSLKSDLARTDLAK  300
            KDFTVFTTRPDTLFGATYAVLAPEHALVDAIT+++QA+AVA YKR ASLKSDLARTDLAK
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  301  EKTGVWTGSYAINPVNGKEIPIWIADYVLASYGTGAIMAVPAHDDRDWEFAKQFDLEIIP  360
            EKTGVWTGSYAINPVNGKE+P+WIADYVLASYGTGAIMAVPAHD+RDWEFAKQF+L+IIP
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  361  VLEGGNVEEAAYTEDGLHINSGFLDGLDKAQAIDKMVSWLEAEGVGNKKVTYRLRDWLFS  420
            VLEGGNVEEAA+TEDGLHINS+FLDGLDKA AI KMV WLEAEGVGN +VTYRLRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  421  RQRYWGEPIPIIHWEDGTTTAVPEDQLPLVLPVTKDIKPSGTGESPLANLTDWLEVTRED  480
            RQRYWGEPIPIIHWEDGT+TAVPE +LPLVLPVTKDI+PSGTGESPLAN+TDWLEVTRED
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKAWLPVDIYIGGAEHAVLHLL  540
            GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLK WLPVDIY+GGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDHRGALVATDKVEKRDGSFFSIET  600
            YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRD RGALVATDKVEKRDGSFF +ET
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  601  GEDLEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660
            GE+LEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  661  LDRVYRLLTTKEIVAENNGNLDKVYNETVKAVTEQLEAMKFNTAIAQLMVFINAANKEDK  720
            LDRVYRL+TTKEI  EN+G LDKVYNETVKAVTEQ++ MKFNTAIAQLMVF+NAANKEDK
Sbjct  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  721  LFADYAKGFIQLLAPFAPHLSEELWQTLTQSGESISYVLWPTWDEAKLVENDVEIVVQIK  780
            LF+DYAKGF+QL+APFAPHL+EELWQ+LT SGESISYV WP+ DE+KLVENDVEIVVQIK
Sbjct  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK  780

Query  781  GKVRAKLVVPKDSSREDLEKLALANDKIQS  810
            GKV+AKLVV+KD SRE+L+ +ALAN+K+Q+
Sbjct  781  GKVKAKLVVAKDLSREELQEVALANEKVQA  810

115) leuS in NC_017486


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1128 bits (4277),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 678/830 (82%), Positives = 762/830 (92%), Gaps = 3/830 (0%)

Query  3    YNHQEIEAKWQKYWADNKTFRTGTDKNKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  62
            Y+H  IE+KWQ +WADN TF+TGTD +KPKFYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRAQGFNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINSLGFSYDWER  122
            R+KRAQG NVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQIN+LGFSYDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVNTTDPNFYKWTQWIFTKLYEKGLAYEAEVAVNWVEELGTAIANEEVLPDGTSERGGYP  182
            EVNTTDPN+YKWTQWIFTKLYEKGLAYEAEV+VNWVEELGTAIANEEVLPDGTSERGGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKEMQRNWIGKSVGADVTFEVAGTDKSF  242
            VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIK+MQRNWIGKS GA+VTF V +TDK F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  243  EVFTTRPDTLFGATYAVLAPEHDLVDAITTPEQKEAVAEYRRKASLKSDLARTDLSKEKT  302
             VFTTRPDTLFGATYAVLAPEH LVDAITT++Q EAVA+Y+R+ASLKSDLARTDL+KEKT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  303  GAFTGAYAINPINGRKMPIWVADYVLASYGHGAVMAVPAHDERDWEFAKVYGLEILPVVE  362
            G  TG+YAINP+NG+ MP+W+ADYVLASYG GA+MAVPAHDERDWEFAK + L+I+PV+E
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  363  GGNVEEAVYTEDGPHINSEFLNGLDKAQAIEKAIEFLEEKKIGKKKITYRLRDWLFSRQR  422
            GGNVEEA +TEDG HINS+FL+GLDKA AI K +E LE   +G+ ++TYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  423  YWGEPIPIIHWEDGTSTALSEDELPLVLPVTSDIKPSGTGESPLANLTDWLEVTRADGLK  482
            YWGEPIPIIHWEDGTSTA++E ELPLVLPVT DI+PSGTGESPLAN+TDWLEVTR DG+K
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  483  GRRETNTMPQWAGSSWYYLRYIDPNNSEALADPELLKEWLPVDIYVGGAEHAVLHLLYAR  542
            GRRETNTMPQWAGSSWYYLRYIDP+N+E LAD ELLK+WLPVDIYVGGAEHAVLHLLYAR
Sbjct  484  GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYAR  543

Query  543  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDHRGALVATDKVEKRDGGFYHMETGEA  602
            FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRD RGALVATDKVEKRDG+F+H+ETGE 
Sbjct  544  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEE  603

Query  603  LEQAPAKMSKSLKNVVNPDDVVEHYGADTLRVYEMFMGPLDASIPWSEEGLEGARKFLDR  662
            LEQAPAKMSKSLKNVVNPDDVVE+YGADTLRVYEMFMGPLDASI+WSEEGLEG+RKFLDR
Sbjct  604  LEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR  663

Query  663  AVRMIENSEIKAENNGELDKVYNETVKNVTERLDLMYFNTAISQLMIFVNAVNKAKALPL  722
              R+I   EI  EN+G LDKVYNETVK VTE++D M FNTAI+QLM+FVNA NK   L  
Sbjct  664  VYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFS  723

Query  723  EYANGFVQLLAPFAPHIAEELWVKL-GNEAGISYVAWPTFDESKLIESEVEIVVQINGkl  781
            +YA+GFVQL+APFAPH++EELW  L ++  +ISYV+WP++DESKL+E++VEIVVQI+GK+
Sbjct  724  DYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKV  783

Query  782  kakikiakdlaREELEKI--GRESVAEALEGKNVVKVIAVPNKLVNIVVK  829
            KAK+ +AKDL+REEL+ +  + E V   + GK+++KVIAVPNKLVNIV+K
Sbjct  784  KAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

116) leuS in NC_002662


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1128 bits (4277),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 678/830 (82%), Positives = 762/830 (92%), Gaps = 3/830 (0%)

Query  3    YNHQEIEAKWQKYWADNKTFRTGTDKNKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  62
            Y+H  IE+KWQ +WADN TF+TGTD +KPKFYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRAQGFNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINSLGFSYDWER  122
            R+KRAQG NVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQIN+LGFSYDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVNTTDPNFYKWTQWIFTKLYEKGLAYEAEVAVNWVEELGTAIANEEVLPDGTSERGGYP  182
            EVNTTDPN+YKWTQWIFTKLYEKGLAYEAEV+VNWVEELGTAIANEEVLPDGTSERGGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKEMQRNWIGKSVGADVTFEVAGTDKSF  242
            VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIK+MQRNWIGKS GA+VTF V +TDK F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  243  EVFTTRPDTLFGATYAVLAPEHDLVDAITTPEQKEAVAEYRRKASLKSDLARTDLSKEKT  302
             VFTTRPDTLFGATYAVLAPEH LVDAITT++Q EAVA+Y+R+ASLKSDLARTDL+KEKT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  303  GAFTGAYAINPINGRKMPIWVADYVLASYGHGAVMAVPAHDERDWEFAKVYGLEILPVVE  362
            G  TG+YAINP+NG+ MP+W+ADYVLASYG GA+MAVPAHDERDWEFAK + L+I+PV+E
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  363  GGNVEEAVYTEDGPHINSEFLNGLDKAQAIEKAIEFLEEKKIGKKKITYRLRDWLFSRQR  422
            GGNVEEA +TEDG HINS+FL+GLDKA AI K +E LE   +G+ ++TYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  423  YWGEPIPIIHWEDGTSTALSEDELPLVLPVTSDIKPSGTGESPLANLTDWLEVTRADGLK  482
            YWGEPIPIIHWEDGTSTA++E ELPLVLPVT DI+PSGTGESPLAN+TDWLEVTR DG+K
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  483  GRRETNTMPQWAGSSWYYLRYIDPNNSEALADPELLKEWLPVDIYVGGAEHAVLHLLYAR  542
            GRRETNTMPQWAGSSWYYLRYIDP+N+E LAD ELLK+WLPVDIYVGGAEHAVLHLLYAR
Sbjct  484  GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYAR  543

Query  543  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDHRGALVATDKVEKRDGGFYHMETGEA  602
            FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRD RGALVATDKVEKRDG+F+H+ETGE 
Sbjct  544  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEE  603

Query  603  LEQAPAKMSKSLKNVVNPDDVVEHYGADTLRVYEMFMGPLDASIPWSEEGLEGARKFLDR  662
            LEQAPAKMSKSLKNVVNPDDVVE+YGADTLRVYEMFMGPLDASI+WSEEGLEG+RKFLDR
Sbjct  604  LEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR  663

Query  663  AVRMIENSEIKAENNGELDKVYNETVKNVTERLDLMYFNTAISQLMIFVNAVNKAKALPL  722
              R+I   EI  EN+G LDKVYNETVK VTE++D M FNTAI+QLM+FVNA NK   L  
Sbjct  664  VYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFS  723

Query  723  EYANGFVQLLAPFAPHIAEELWVKL-GNEAGISYVAWPTFDESKLIESEVEIVVQINGkl  781
            +YA+GFVQL+APFAPH++EELW  L ++  +ISYV+WP++DESKL+E++VEIVVQI+GK+
Sbjct  724  DYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKV  783

Query  782  kakikiakdlaREELEKI--GRESVAEALEGKNVVKVIAVPNKLVNIVVK  829
            KAK+ +AKDL+REEL+ +  + E V   + GK+++KVIAVPNKLVNIV+K
Sbjct  784  KAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

117) leuS in NC_009004


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1127 bits (4275),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 678/830 (82%), Positives = 762/830 (92%), Gaps = 3/830 (0%)

Query  3    YNHQKIEAKWQKYWADNKTFRTGTDKNKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  62
            Y+H  IE+KWQ +WADN TF+TGTD +KPKFYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRAQGFNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINSLGFSYDWER  122
            R+KRAQG NVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQIN+LGFSYDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVNTTDPNFYKWTQWIFTKLYEKGLAYEAEVAVNWVEELGTAIANEEVLPDGTSERGGYP  182
            EVNTTDPN+YKWTQWIFTKLYEKGLAYEAEV+VNWVEELGTAIANEEVLPDGTSERGGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKEMQRNWIGKSVGADVTFEVAGTDKSF  242
            VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIK+MQRNWIGKS GA+VTF V +TDK F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  243  EVFTTRPDTLFGATYAVLAPEHDLVDAITTPEQKEAVAEYRRKASLKSDLARTDLSKEKT  302
             VFTTRPDTLFGATYAVLAPEH LVDAITT++Q EAVA+Y+R+ASLKSDLARTDL+KEKT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  303  GAFTGAYAINPINGRKMPIWVADYVLASYGHGAVMAVPAHDERDWEFAKVYGLEILPVVE  362
            G  TG+YAINP+NG+ MP+W+ADYVLASYG GA+MAVPAHDERDWEFAK + L+I+PV+E
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  363  GGNVEEAVYTEDGPHINSEFLNGLDKAQAIEKAIEFLEEKKIGKKKITYRLRDWLFSRQR  422
            GGNVEEA +TEDG HINS+FL+GLDKA AI K +E LE   +G+ ++TYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  423  YWGEPIPIIHWEDGTSTALSEDELPLVLPVTSDIKPSGTGESPLANLTDWLEVTRADGLK  482
            YWGEPIPIIHWEDGTSTA++E ELPLVLPVT DI+PSGTGESPLAN+TDWLEVTR DG+K
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  483  GRRETNTMPQWAGSSWYYLRYIDPNNSEALADPELLKEWLPVDIYVGGAEHAVLHLLYAR  542
            GRRETNTMPQWAGSSWYYLRYIDP+N+E LAD ELLK+WLPVDIYVGGAEHAVLHLLYAR
Sbjct  484  GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYAR  543

Query  543  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDHRGALVATDKVEKRDGGFYHMETGEA  602
            FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRD RGALVATDKVEKRDG+F+H+ETGE 
Sbjct  544  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEE  603

Query  603  LEQAPAKMSKSLKNVVNPDDVVEHYGADTLRVYEMFMGPLDASIPWSEEGLEGARKFLDR  662
            LEQAPAKMSKSLKNVVNPDDVVE+YGADTLRVYEMFMGPLDASI+WSEEGLEG+RKFLDR
Sbjct  604  LEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR  663

Query  663  AVRMIENSEIKAENNGELDKVYNETVKNVTERLDLMYFNTAISQLMIFVNAVNKAKALPL  722
              R+I   EI  EN+G LDKVYNETVK VTE++D M FNTAI+QLM+FVNA NK   L  
Sbjct  664  VYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFS  723

Query  723  EYANGFVQLLAPFAPHIAEELWVKL-GNEAGISYVAWPTFDESKLIESEVEIVVQINGkl  781
            +YA+GFVQL+APFAPH++EELW  L ++  +ISYV+WP++DESKL+E++VEIVVQI+GK+
Sbjct  724  DYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKV  783

Query  782  kakikiakdlaREELEKI--GRESVAEALEGKNVVKVIAVPNKLVNIVVK  829
            KAK+ +AKDL+REEL+ +  + E V   + GK+++KVIAVPNKLVNIV+K
Sbjct  784  KAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

118) leuS in NC_017949


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1127 bits (4275),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 678/830 (82%), Positives = 762/830 (92%), Gaps = 3/830 (0%)

Query  3    YNHQKIEAKWQKYWADNKTFRTGTDKNKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  62
            Y+H  IE+KWQ +WADN TF+TGTD +KPKFYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRAQGFNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINSLGFSYDWER  122
            R+KRAQG NVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQIN+LGFSYDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVNTTDPNFYKWTQWIFTKLYEKGLAYEAEVAVNWVEELGTAIANEEVLPDGTSERGGYP  182
            EVNTTDPN+YKWTQWIFTKLYEKGLAYEAEV+VNWVEELGTAIANEEVLPDGTSERGGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKEMQRNWIGKSVGADVTFEVAGTDKSF  242
            VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIK+MQRNWIGKS GA+VTF V +TDK F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  243  EVFTTRPDTLFGATYAVLAPEHDLVDAITTPEQKEAVAEYRRKASLKSDLARTDLSKEKT  302
             VFTTRPDTLFGATYAVLAPEH LVDAITT++Q EAVA+Y+R+ASLKSDLARTDL+KEKT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  303  GAFTGAYAINPINGRKMPIWVADYVLASYGHGAVMAVPAHDERDWEFAKVYGLEILPVVE  362
            G  TG+YAINP+NG+ MP+W+ADYVLASYG GA+MAVPAHDERDWEFAK + L+I+PV+E
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  363  GGNVEEAVYTEDGPHINSEFLNGLDKAQAIEKAIEFLEEKKIGKKKITYRLRDWLFSRQR  422
            GGNVEEA +TEDG HINS+FL+GLDKA AI K +E LE   +G+ ++TYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  423  YWGEPIPIIHWEDGTSTALSEDELPLVLPVTSDIKPSGTGESPLANLTDWLEVTRADGLK  482
            YWGEPIPIIHWEDGTSTA++E ELPLVLPVT DI+PSGTGESPLAN+TDWLEVTR DG+K
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  483  GRRETNTMPQWAGSSWYYLRYIDPNNSEALADPELLKEWLPVDIYVGGAEHAVLHLLYAR  542
            GRRETNTMPQWAGSSWYYLRYIDP+N+E LAD ELLK+WLPVDIYVGGAEHAVLHLLYAR
Sbjct  484  GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYAR  543

Query  543  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDHRGALVATDKVEKRDGGFYHMETGEA  602
            FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRD RGALVATDKVEKRDG+F+H+ETGE 
Sbjct  544  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEE  603

Query  603  LEQAPAKMSKSLKNVVNPDDVVEHYGADTLRVYEMFMGPLDASIPWSEEGLEGARKFLDR  662
            LEQAPAKMSKSLKNVVNPDDVVE+YGADTLRVYEMFMGPLDASI+WSEEGLEG+RKFLDR
Sbjct  604  LEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR  663

Query  663  AVRMIENSEIKAENNGELDKVYNETVKNVTERLDLMYFNTAISQLMIFVNAVNKAKALPL  722
              R+I   EI  EN+G LDKVYNETVK VTE++D M FNTAI+QLM+FVNA NK   L  
Sbjct  664  VYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFS  723

Query  723  EYANGFVQLLAPFAPHIAEELWVKL-GNEAGISYVAWPTFDESKLIESEVEIVVQINGkl  781
            +YA+GFVQL+APFAPH++EELW  L ++  +ISYV+WP++DESKL+E++VEIVVQI+GK+
Sbjct  724  DYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKV  783

Query  782  kakikiakdlaREELEKI--GRESVAEALEGKNVVKVIAVPNKLVNIVVK  829
            KAK+ +AKDL+REEL+ +  + E V   + GK+++KVIAVPNKLVNIV+K
Sbjct  784  KAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

119) leuS in NC_020450


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1127 bits (4273),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 677/830 (82%), Positives = 761/830 (92%), Gaps = 3/830 (0%)

Query  3    YNHQEIEAKWQKYWADNKTFRTGTDKNKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  62
            Y+H  IE+KWQ +WADN TF+TGTD +KPKFYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRAQGFNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINSLGFSYDWER  122
            R+KRAQG NVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQIN+LGFSYDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVNTTDPNFYKWTQWIFTKLYEKGLAYEAEVAVNWVEELGTAIANEEVLPDGTSERGGYP  182
            EVNTTDPN+YKWTQWIFTKLYEKGLAYEAEV+VNWVEELGTAIANEEVLPDGTSERGGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKEMQRNWIGKSVGADVTFEVAGTDKSF  242
            VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIK+MQRNWIGKS GA+VTF V +TDK F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  243  EVFTTRPDTLFGATYAVLAPEHDLVDAITTAEQKEAVAEYRRKASLKSDLARTDLSKEKT  302
             VFTTRPDTLFGATYAVLAPEH LVDAITT++Q EAVA+Y+R+ASLKSDLARTDL+KEKT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  303  GAFTGAYAINPINGRKMPIWVADYVLASYGHGAVMAVPAHDERDWEFAKVYGLEILPVVE  362
            G  TG+YAINP+NG+ MP+W+ADYVLASYG GA+MAVPAHDERDWEFAK + L+I+PV+E
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  363  GGNVEKAVYTEDGPHINSEFLNGLDKAQAIEKAIEFLEEKKIGKKKITYRLRDWLFSRQR  422
            GGNVE A +TEDG HINS+FL+GLDKA AI K +E LE   +G+ ++TYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  423  YWGEPIPIIHWEDGTSTALSEDELPLVLPVTSDIKPSGTGESPLANLTDWLEVTRADGLK  482
            YWGEPIPIIHWEDGTSTA++E ELPLVLPVT DI+PSGTGESPLAN+TDWLEVTR DG+K
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  483  GRRETNTMPQWAGSSWYYLRYIDPNNSEALADPELLKEWLPVDIYVGGAEHAVLHLLYAR  542
            GRRETNTMPQWAGSSWYYLRYIDP+N+E LAD ELLK+WLPVDIYVGGAEHAVLHLLYAR
Sbjct  484  GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYAR  543

Query  543  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDHRGALVATDKVEKRDGGFYHMETGEA  602
            FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRD RGALVATDKVEKRDG+F+H+ETGE 
Sbjct  544  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEE  603

Query  603  LEQAPAKMSKSLKNVVNPDDVVEHYGADTLRVYEMFMGPLDASIPWSEEGLEGARKFLDR  662
            LEQAPAKMSKSLKNVVNPDDVVE+YGADTLRVYEMFMGPLDASI+WSEEGLEG+RKFLDR
Sbjct  604  LEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR  663

Query  663  AVRMIENSEIKAENNGELDKVYNETVKNVTERLDLMYFNTAISQLMIFVNAVNKAKALPL  722
              R+I   EI  EN+G LDKVYNETVK VTE++D M FNTAI+QLM+FVNA NK   L  
Sbjct  664  VYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFS  723

Query  723  EYANGFVQLLAPFAPHIAEELWVKL-GNEAGISYVAWPTFDESKLIESEVEIVVQINGkl  781
            +YA+GFVQL+APFAPH++EELW  L ++  +ISYV+WP++DESKL+E++VEIVVQI+GK+
Sbjct  724  DYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKV  783

Query  782  kakikiakdlaREELEKI--GRESVAEALEGKNVVKVIAVPNKLVNIVVK  829
            KAK+ +AKDL+REEL+ +  + E V   + GK+++KVIAVPNKLVNIV+K
Sbjct  784  KAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

120) leuS in NC_013656


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1127 bits (4274),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 676/830 (82%), Positives = 762/830 (92%), Gaps = 3/830 (0%)

Query  3    YNHQEIEAKWQKYWAENKTFRTGTDKNKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  62
            Y+H  IE+KWQ +WA+N TF+TGTD +KPKFYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRAQGFNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINSLGFSYDWER  122
            R+KRAQG NVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQIN+LGFSYDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVNTTDPNFYKWTQWIFTKLYEKGLAYEAEVAVNWVEELGTAIANEEVLPDGTSERGGYP  182
            EVNTTDPN+YKWTQWIFTKLYEKGLAYEAEV+VNWVEELGTAIANEEVLPDGTSERGGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKEMQRNWIGKSVGADVTFEVAGTDKSF  242
            VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIK+MQRNWIGKS GA+VTF V +TDK F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  243  EVFTTRPDTLFGATYAVLAPEHDLVDAITTPEQKEAVAEYRRKASLKSDLARTDLSKEKT  302
             VFTTRPDTLFGATYAVLAPEH LVDAITT++Q EAVA+Y+R+ASLKSDLARTDL+KEKT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  303  GAFTGAYAINPINGRKMPIWVADYVLASYGHGAVMAVPAHDERDWEFAKVYGLEILPVVE  362
            G  TG+YAINP+NG+ MP+W+ADYVLASYG GA+MAVPAHDERDWEFAK + L+I+PV+E
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  363  GGNVEEAVYTEDGPHINSEFLNGLDKAQAIEKAIEFLEEKKIGKKKITYRLRDWLFSRQR  422
            GGNVEEA +TEDG HINS+FL+GLDKA AI K +E LE   +G+ ++TYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  423  YWGEPIPIIHWENGTSTALSEDELPLVLPVTSDIKPSGTGESPLANLTDWLEVTRADGLK  482
            YWGEPIPIIHWE+GTSTA++E ELPLVLPVT DI+PSGTGESPLAN+TDWLEVTR DG+K
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  483  GRRETNTMPQWAGSSWYYLRYIDPNNSEALADPELLKEWLPVDIYVGGAEHAVLHLLYAR  542
            GRRETNTMPQWAGSSWYYLRYIDP+N+E LAD ELLK+WLPVDIYVGGAEHAVLHLLYAR
Sbjct  484  GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYAR  543

Query  543  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDHRGALVATDKVEKRDGGFYHMETGEA  602
            FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRD RGALVATDKVEKRDG+F+H+ETGE 
Sbjct  544  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEE  603

Query  603  LEQAPAKMSKSLKNVVNPDDVVEHYGADTLRVYEMFMGPLDASIPWSEEGLEGARKFLDR  662
            LEQAPAKMSKSLKNVVNPDDVVE+YGADTLRVYEMFMGPLDASI+WSEEGLEG+RKFLDR
Sbjct  604  LEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR  663

Query  663  AVRMIENSEIKAENNGELDKVYNETVKNVTERLDLMYFNTAISQLMIFVNAVNKAKALPL  722
              R+I   EI  EN+G LDKVYNETVK VTE++D M FNTAI+QLM+FVNA NK   L  
Sbjct  664  VYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFS  723

Query  723  EYANGFVQLLAPFAPHIAEELWVKL-GNEAGISYVAWPTFDESKLIESEVEIVVQINGkl  781
            +YA+GFVQL+APFAPH++EELW  L ++  +ISYV+WP++DESKL+E++VEIVVQI+GK+
Sbjct  724  DYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKV  783

Query  782  kakikiakdlaREELEKI--GRESVAEALEGKNVVKVIAVPNKLVNIVVK  829
            KAK+ +AKDL+REEL+ +  + E V   + GK+++KVIAVPNKLVNIV+K
Sbjct  784  KAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

121) LCGT_0691 in NC_015930


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1126 bits (4271),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 659/830 (80%), Positives = 764/830 (93%), Gaps = 6/830 (0%)

Query  3    YKHIDIEAKWQKYWADNNTFRTGTDKNKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  62
            Y H  IE+KWQ +WADN+TF+TGTD +KPKFYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRAQGYNVLHPMGWDAFGLPAEQYAIDTGNDPVEFTAKNIATFKRQINSLGFSYDWER  122
            R+KRAQG NVLHPMGWDAFGLPAEQYA+DTGNDP EFTA NIA FKRQIN+LGFSYDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVNTTDPEFYKWTQWIFTKLYEKGLAYEAEVAVNWVEELGTAIANEEVLPDGTSERGGYP  182
            EVNTTDP++YKWTQWIFTKLYEKGLAYEAEV+VNWVEELGTAIANEEVLPDGTSERGGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VVRKPMRQWMLKITAYAERLLNDLEDLDWPESIKEMQRNWIGKSVGADINFKVEGSDEEF  242
            VVRKPMRQWMLKITAYAERLL+DLE++DWPESIK+MQRNWIGKS GA++ FKV ++D +F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  243  TVFTTRPETLFGSTFAVLAPEHPLVEKITTAEQADAVEDYKHQASLKSDLARTDLAKDKT  302
            TVFTTRP+TLFG+T+AVLAPEH+LV+ ITT++QA+AV DYK+QASLKSDLARTDLAK+KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  303  GVWTGAYAINPVSGKKMPIWIADYVLASYGHGAVMAVPGHDERDWEFAKVYDLEIVPVFD  362
            GVWTG+YAINPV+GK MP+WIADYVLASYG GA+MAVP+HDERDWEFAK ++L+I+PV++
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  363  GGNVQEACHVEGGKIINSDFLNGMEKEAAIEKMVAYLEEKGIGSRKVTYRLRDWLFSRQR  422
            GGNV+EA   E+G  INSDFL+G++K +AI KMV  LE  G+G+ +VTYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  423  YWGEPIPIIHWEDGTTTAVPEEELPLVLPKTSNIKPSGTGESPLANLTDWLTVTREDGVK  482
            YWGEPIPIIHWEDGT+TAVPE ELPLVLP T +I+PSGTGESPLAN+TDWL VTREDGVK
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  483  GRRETNTMPQWAGSSWYYLRYIDPKNSQAIADPELIKEWLPVDIYVGGAEHAVLHLLYAR  542
            GRRETNTMPQWAGSSWYYLRYIDP N++ +AD EL+K+WLPVDIYVGGAEHAVLHLLYAR
Sbjct  484  GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYAR  543

Query  543  FWHKVLFDLGVVPTNEPFQKLFNQGMILGTSYRDSRGALVATDKVEKREGSYYNIETGEE  602
            FWHKVL+DLGVVPT+EPFQKLFNQGMILGTSYRDSRGALVATDKVEKR+GS++++ETGEE
Sbjct  544  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEE  603

Query  603  LEQAPAKMSKSLKNVVNPDDVVKRYGADTLRVYEMFMGPLDASIPWSEEGLEGARKFLDR  662
            LEQAPAKMSKSLKNVVNPDDVV +YGADTLRVYEMFMGPLDASI+WSEEGLEG+RKFLDR
Sbjct  604  LEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR  663

Query  663  VVRLLSNSTITEENDGSLDKVYNETVKNVTERLDHMLFNTAISQLMIFVNAANKAKTLPL  722
            V RL++   ITEEN G+LDKVYNETVK VTE++D+M FNTAI+QLM+FVNAANK   L  
Sbjct  664  VYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFS  723

Query  723  EYAKGFVQLLAPFAPHLAEELWVEL-GNEAGISYVAWPSFDESKLVEDEIEIVVQINGKL  781
            +YAKGFVQL+APFAPHL+EELW  L ++  +ISYV+WPS+DESKLVE+++EIVVQI+GK+
Sbjct  724  DYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKV  783

Query  782  KAKVMIEKDLPKDQlekvaleaveveG-----NIVKVIAIPNKLVNIVVK  826
            KAK+++ KDL++++L+ VAL    V++     +I+KVIA+PNKLVNIV+K
Sbjct  784  KAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

122) LCGL_0711 in NC_017490


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1126 bits (4271),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 659/830 (80%), Positives = 764/830 (93%), Gaps = 6/830 (0%)

Query  3    YKHIDIEAKWQKYWADNNTFRTGTDKNKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  62
            Y H  IE+KWQ +WADN+TF+TGTD +KPKFYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRAQGYNVLHPMGWDAFGLPAEQYAIDTGNDPVEFTAKNIATFKRQINSLGFSYDWER  122
            R+KRAQG NVLHPMGWDAFGLPAEQYA+DTGNDP EFTA NIA FKRQIN+LGFSYDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVNTTDPEFYKWTQWIFTKLYEKGLAYEAEVAVNWVEELGTAIANEEVLPDGTSERGGYP  182
            EVNTTDP++YKWTQWIFTKLYEKGLAYEAEV+VNWVEELGTAIANEEVLPDGTSERGGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VVRKPMRQWMLKITAYAERLLNDLEDLDWPESIKEMQRNWIGKSVGADINFKVEGSDEEF  242
            VVRKPMRQWMLKITAYAERLL+DLE++DWPESIK+MQRNWIGKS GA++ FKV ++D +F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  243  TVFTTRPETLFGSTFAVLAPEHPLVEKITTAEQADAVEDYKHQASLKSDLARTDLAKDKT  302
            TVFTTRP+TLFG+T+AVLAPEH+LV+ ITT++QA+AV DYK+QASLKSDLARTDLAK+KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  303  GVWTGAYAINPVSGKKMPIWIADYVLASYGHGAVMAVPGHDERDWEFAKVYDLEIVPVFD  362
            GVWTG+YAINPV+GK MP+WIADYVLASYG GA+MAVP+HDERDWEFAK ++L+I+PV++
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  363  GGNVQEACHVEGGKIINSDFLNGMEKEAAIEKMVAYLEEKGIGSRKVTYRLRDWLFSRQR  422
            GGNV+EA   E+G  INSDFL+G++K +AI KMV  LE  G+G+ +VTYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  423  YWGEPIPIIHWEDGTTTAVPEEELPLVLPKTSNIKPSGTGESPLANLTDWLTVTREDGVK  482
            YWGEPIPIIHWEDGT+TAVPE ELPLVLP T +I+PSGTGESPLAN+TDWL VTREDGVK
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  483  GRRETNTMPQWAGSSWYYLRYIDPKNSQAIADPELIKEWLPVDIYVGGAEHAVLHLLYAR  542
            GRRETNTMPQWAGSSWYYLRYIDP N++ +AD EL+K+WLPVDIYVGGAEHAVLHLLYAR
Sbjct  484  GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYAR  543

Query  543  FWHKVLFDLGVVPTNEPFQKLFNQGMILGTSYRDSRGALVATDKVEKREGSYYNIETGEE  602
            FWHKVL+DLGVVPT+EPFQKLFNQGMILGTSYRDSRGALVATDKVEKR+GS++++ETGEE
Sbjct  544  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEE  603

Query  603  LEQAPAKMSKSLKNVVNPDDVVKRYGADTLRVYEMFMGPLDASIPWSEEGLEGARKFLDR  662
            LEQAPAKMSKSLKNVVNPDDVV +YGADTLRVYEMFMGPLDASI+WSEEGLEG+RKFLDR
Sbjct  604  LEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR  663

Query  663  VVRLLSNSTITEENDGSLDKVYNETVKNVTERLDHMLFNTAISQLMIFVNAANKAKTLPL  722
            V RL++   ITEEN G+LDKVYNETVK VTE++D+M FNTAI+QLM+FVNAANK   L  
Sbjct  664  VYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFS  723

Query  723  EYAKGFVQLLAPFAPHLAEELWVEL-GNEAGISYVAWPSFDESKLVEDEIEIVVQINGKL  781
            +YAKGFVQL+APFAPHL+EELW  L ++  +ISYV+WPS+DESKLVE+++EIVVQI+GK+
Sbjct  724  DYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKV  783

Query  782  KAKVMIEKDLPKDQlekvaleaveveG-----NIVKVIAIPNKLVNIVVK  826
            KAK+++ KDL++++L+ VAL    V++     +I+KVIA+PNKLVNIV+K
Sbjct  784  KAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

123) llh_8685 in NC_017492


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1117 bits (4235),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 687/830 (83%), Positives = 770/830 (93%), Gaps = 3/830 (0%)

Query  3    YNHQEIEAKWQKFWADNQTFRTGTDKTKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  62
            Y+H  IE+KWQ FWADN+TF+TGTD +KPKFYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRAQGFNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINSLGFSYDWER  122
            R+KRAQG NVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQIN+LGFSYDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVNTTDPNFYKWTQWIFTKLYEKGLAYEAEVAVNWVEELGTAIANEEVLPDGTSERGGYP  182
            EVNTTDPN+YKWTQWIFTKLYEKGLAYEAEV+VNWVEELGTAIANEEVLPDGTSERGGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKEMQRNWIGKSVGADVTFKVEGTDKSF  242
            VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIK+MQRNWIGKS GA+VTFKV +TDK F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  243  EVFTTRPDTLFGATYAVLAPEHDLVDAITTPEQVQAVADYRRQASLKSDLARTDLAKEKT  302
             VFTTRPDTLFGATYAVLAPEH LVDAITT++Q +AVADY+RQASLKSDLARTDLAKEKT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  303  GAFTGAYAINPINGRKMPIWVADYVLASYGHGAVMAVPAHDERDWEFAKVYGLEILPVVE  362
            G  TG+YAINP+NG+ MP+W+ADYVLASYG GA+MAVPAHDERDWEFAK + L+I+PV+E
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  363  GGNVEEAVYTEDGPHINSEFLNGLDKAQAIEKAIEFLEEKKIGKKKITYRLRDWLFSRQR  422
            GGNVEEA +TEDG HINS+FL+GLDKA AI K +E LE   +G+ ++TYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  423  YWGEPIPIIHWEDGTSTAlpenelplvlpvTSDIKPSGTGESPLANLTDWLEVTREDGVK  482
            YWGEPIPIIHWEDGTSTA+PE+ELPLVLPVT DI+PSGTGESPLAN+TDWLEVTREDGVK
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  483  GRRETNTMPQWAGSSWYYLRYIDPHNTEALADPELLKEWLPVDIYVGGAEHAVLHLLYAR  542
            GRRETNTMPQWAGSSWYYLRYIDPHNTE LAD ELLK+WLPVDIYVGGAEHAVLHLLYAR
Sbjct  484  GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYAR  543

Query  543  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDHRGALVATDKVEKRDGGFYHMETGEE  602
            FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRD RGALVATDKVEKRDG+F+H+ETGEE
Sbjct  544  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEE  603

Query  603  LEQAPAKMSKSLKNVVNPDDVVEHYGADTLRVYEMFMGPLDASIPWSEEGLEGARKFLDR  662
            LEQAPAKMSKSLKNVVNPDDVVE+YGADTLRVYEMFMGPLDASI+WSEEGLEG+RKFLDR
Sbjct  604  LEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR  663

Query  663  VVRMIDNSEISDKNNGELDKVYNETVKNVSERLDLMYFNTAISQLMIFVNATNKAKILPL  722
            V R+I   EI++ N+G LDKVYNETVK V+E++D M FNTAI+QLM+FVNA+NK   L  
Sbjct  664  VYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFS  723

Query  723  EYANGFVQLLAPFAPHIAEELWVKL-GNEAGISYVAWPTFDESKLVESEVEIVVQINgkl  781
            +YA+GFVQL+APFAPH++EELW  L ++  +ISYV+WP++DESKLVE++VEIVVQI+GK+
Sbjct  724  DYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKV  783

Query  782  kakikiakdlgRDELEKI--GREAVAEALEGKNVVKVIAVPNKLVNIVVK  829
            KAK+ +AKDL+R+EL+ +  + E V   + GK+++KVIAVPNKLVNIV+K
Sbjct  784  KAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

124) leuS in NC_008527


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1117 bits (4235),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 687/830 (83%), Positives = 770/830 (93%), Gaps = 3/830 (0%)

Query  3    YNHQEIEAKWQKFWADNQTFRTGTDKTKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  62
            Y+H  IE+KWQ FWADN+TF+TGTD +KPKFYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRAQGFNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINSLGFSYDWER  122
            R+KRAQG NVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQIN+LGFSYDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVNTTDPNFYKWTQWIFTKLYEKGLAYEAEVAVNWVEELGTAIANEEVLPDGTSERGGYP  182
            EVNTTDPN+YKWTQWIFTKLYEKGLAYEAEV+VNWVEELGTAIANEEVLPDGTSERGGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKEMQRNWIGKSVGADVTFKVEGTDKSF  242
            VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIK+MQRNWIGKS GA+VTFKV +TDK F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  243  EVFTTRPDTLFGATYAVLAPEHDLVDAITTPEQVQAVADYRRQASLKSDLARTDLAKEKT  302
             VFTTRPDTLFGATYAVLAPEH LVDAITT++Q +AVADY+RQASLKSDLARTDLAKEKT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  303  GAFTGAYAINPINGRKMPIWVADYVLASYGHGAVMAVPAHDERDWEFAKVYGLEILPVVE  362
            G  TG+YAINP+NG+ MP+W+ADYVLASYG GA+MAVPAHDERDWEFAK + L+I+PV+E
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  363  GGNVEEAVYTEDGPHINSEFLNGLDKAQAIEKAIEFLEEKKIGKKKITYRLRDWLFSRQR  422
            GGNVEEA +TEDG HINS+FL+GLDKA AI K +E LE   +G+ ++TYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  423  YWGEPIPIIHWEDGTSTAlpenelplvlpvTSDIKPSGTGESPLANLTDWLEVTREDGVK  482
            YWGEPIPIIHWEDGTSTA+PE+ELPLVLPVT DI+PSGTGESPLAN+TDWLEVTREDGVK
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  483  GRRETNTMPQWAGSSWYYLRYIDPHNTEALADPELLKEWLPVDIYVGGAEHAVLHLLYAR  542
            GRRETNTMPQWAGSSWYYLRYIDPHNTE LAD ELLK+WLPVDIYVGGAEHAVLHLLYAR
Sbjct  484  GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYAR  543

Query  543  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDHRGALVATDKVEKRDGGFYHMETGEE  602
            FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRD RGALVATDKVEKRDG+F+H+ETGEE
Sbjct  544  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEE  603

Query  603  LEQAPAKMSKSLKNVVNPDDVVEHYGADTLRVYEMFMGPLDASIPWSEEGLEGARKFLDR  662
            LEQAPAKMSKSLKNVVNPDDVVE+YGADTLRVYEMFMGPLDASI+WSEEGLEG+RKFLDR
Sbjct  604  LEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR  663

Query  663  VVRMIDNSEISDKNNGELDKVYNETVKNVSERLDLMYFNTAISQLMIFVNATNKAKILPL  722
            V R+I   EI++ N+G LDKVYNETVK V+E++D M FNTAI+QLM+FVNA+NK   L  
Sbjct  664  VYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFS  723

Query  723  EYANGFVQLLAPFAPHIAEELWVKL-GNEAGISYVAWPTFDESKLVESEVEIVVQINgkl  781
            +YA+GFVQL+APFAPH++EELW  L ++  +ISYV+WP++DESKLVE++VEIVVQI+GK+
Sbjct  724  DYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKV  783

Query  782  kakikiakdlgRDELEKI--GREAVAEALEGKNVVKVIAVPNKLVNIVVK  829
            KAK+ +AKDL+R+EL+ +  + E V   + GK+++KVIAVPNKLVNIV+K
Sbjct  784  KAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

125) leuS in NC_019435


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1117 bits (4235),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 687/830 (83%), Positives = 770/830 (93%), Gaps = 3/830 (0%)

Query  3    YNHQEIEAKWQKFWADNQTFRTGTDKTKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  62
            Y+H  IE+KWQ FWADN+TF+TGTD +KPKFYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRAQGFNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINSLGFSYDWER  122
            R+KRAQG NVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQIN+LGFSYDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVNTTDPNFYKWTQWIFTKLYEKGLAYEAEVAVNWVEELGTAIANEEVLPDGTSERGGYP  182
            EVNTTDPN+YKWTQWIFTKLYEKGLAYEAEV+VNWVEELGTAIANEEVLPDGTSERGGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKEMQRNWIGKSVGADVTFKVEGTDKSF  242
            VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIK+MQRNWIGKS GA+VTFKV +TDK F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  243  EVFTTRPDTLFGATYAVLAPEHDLVDAITTPEQVQAVADYRRQASLKSDLARTDLAKEKT  302
             VFTTRPDTLFGATYAVLAPEH LVDAITT++Q +AVADY+RQASLKSDLARTDLAKEKT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  303  GAFTGAYAINPINGRKMPIWVADYVLASYGHGAVMAVPAHDERDWEFAKVYGLEILPVVE  362
            G  TG+YAINP+NG+ MP+W+ADYVLASYG GA+MAVPAHDERDWEFAK + L+I+PV+E
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  363  GGNVEEAVYTEDGPHINSEFLNGLDKAQAIEKAIEFLEEKKIGKKKITYRLRDWLFSRQR  422
            GGNVEEA +TEDG HINS+FL+GLDKA AI K +E LE   +G+ ++TYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  423  YWGEPIPIIHWEDGTSTAlpenelplvlpvTSDIKPSGTGESPLANLTDWLEVTREDGVK  482
            YWGEPIPIIHWEDGTSTA+PE+ELPLVLPVT DI+PSGTGESPLAN+TDWLEVTREDGVK
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  483  GRRETNTMPQWAGSSWYYLRYIDPHNTEALADPELLKEWLPVDIYVGGAEHAVLHLLYAR  542
            GRRETNTMPQWAGSSWYYLRYIDPHNTE LAD ELLK+WLPVDIYVGGAEHAVLHLLYAR
Sbjct  484  GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYAR  543

Query  543  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDHRGALVATDKVEKRDGGFYHMETGEE  602
            FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRD RGALVATDKVEKRDG+F+H+ETGEE
Sbjct  544  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEE  603

Query  603  LEQAPAKMSKSLKNVVNPDDVVEHYGADTLRVYEMFMGPLDASIPWSEEGLEGARKFLDR  662
            LEQAPAKMSKSLKNVVNPDDVVE+YGADTLRVYEMFMGPLDASI+WSEEGLEG+RKFLDR
Sbjct  604  LEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR  663

Query  663  VVRMIDNSEISDKNNGELDKVYNETVKNVSERLDLMYFNTAISQLMIFVNATNKAKILPL  722
            V R+I   EI++ N+G LDKVYNETVK V+E++D M FNTAI+QLM+FVNA+NK   L  
Sbjct  664  VYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFS  723

Query  723  EYANGFVQLLAPFAPHIAEELWVKL-GNEAGISYVAWPTFDESKLVESEVEIVVQINgkl  781
            +YA+GFVQL+APFAPH++EELW  L ++  +ISYV+WP++DESKLVE++VEIVVQI+GK+
Sbjct  724  DYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKV  783

Query  782  kakikiakdlgRDELEKI--GREAVAEALEGKNVVKVIAVPNKLVNIVVK  829
            KAK+ +AKDL+R+EL+ +  + E V   + GK+++KVIAVPNKLVNIV+K
Sbjct  784  KAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

126) leuS in NC_022369


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score = 1116 bits (4231),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 686/830 (83%), Positives = 769/830 (93%), Gaps = 3/830 (0%)

Query  3    YNHQEIEAKWQKFWADNQTFRTGTDKTKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  62
            Y+H  IE+KWQ FWADN+TF+TGTD +KPKFYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRAQGFNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINSLGFSYDWER  122
            R+KRAQG NVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQIN+LGFSYDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVNTTDPNFYKWTQWIFTKLYEKGLAYEAEVAVNWVEELGTAIANEEVLPDGTSERGGYP  182
            EVNTTDPN+YKWTQWIFTKLYEKGLAYEAEV+VNWVEELGTAIANEEVLPDGTSERGGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKEMQRNWIGKSVGADVTFKVEGTDKSF  242
            VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIK+MQRNWIGKS GA+VTFKV +TDK F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  243  EVFTTRPDTLFGATYAVLAPEHDLVDAITTPEQVQAVADYRRQASLKSDLARTDLAKEKT  302
             VFTTRPDTLFGATYAVLAPEH LVDAITT++Q +AVADY+RQASLKSDLARTDLAKEKT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  303  GAFTGAYAINPINGRKMPIWVADYVLASYGHGAVMAVPAHDERDWEFAKVYGLEILPVVE  362
            G  TG+YAINP+NG+ MP+W+ADYVLASYG GA+MAVPAHDERDWEFAK + L+I+PV+E
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  363  GGNVEEAVYTEDGPHINSEFLNGLDKAQAIEKAIEFLEEKKIGKKKITYRLRDWLFSRQR  422
            GGNVEEA +TEDG HINS+FL+GLDKA AI K +E LE   +G+ ++TYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  423  YWGEPIPIIHWEDGTSTAlpenelplvlpvTSDIKPSGTGESPLANLTDWLEVTREDGVK  482
            YWGEPIPIIHWEDGTSTA+PE+ELPLVLPVT DI+PSGTGESPLAN+TDWLEVTREDGVK
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  483  GRRETNTMPQWAGSSWYYLRYIDPHNTEALADSDLLKEWLPVDIYVGGAEHAVLHLLYAR  542
            GRRETNTMPQWAGSSWYYLRYIDPHNTE LAD +LLK+WLPVDIYVGGAEHAVLHLLYAR
Sbjct  484  GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYAR  543

Query  543  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDHRGALVATDKVEKRDGGFYHMETGEE  602
            FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRD RGALVATDKVEKRDG+F+H+ETGEE
Sbjct  544  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEE  603

Query  603  LEQAPAKMSKSLKNVVNPDDVVEHYGADTLRVYEMFMGPLDASIPWSEEGLEGARKFLDR  662
            LEQAPAKMSKSLKNVVNPDDVVE+YGADTLRVYEMFMGPLDASI+WSEEGLEG+RKFLDR
Sbjct  604  LEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR  663

Query  663  VVRMIDNSEISDKNNGELDKVYNETVKNVTERLDLMYFNTAISQLMIFVNATNKAKVLPL  722
            V R+I   EI++ N+G LDKVYNETVK VTE++D M FNTAI+QLM+FVNA+NK   L  
Sbjct  664  VYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFS  723

Query  723  EYANGFVQLLAPFAPHIAEELWVKL-GNEAGISYVAWPTFDESKLVESEVEIVVQINgkl  781
            +YA+GFVQL+APFAPH++EELW  L ++  +ISYV+WP++DESKLVE++VEIVVQI+GK+
Sbjct  724  DYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKV  783

Query  782  kakikiakdlgRDELEKI--GREAVAEALEGENVVKVIAVPNKLVNIVVK  829
            KAK+ +AKDL+R+EL+ +  + E V   + G +++KVIAVPNKLVNIV+K
Sbjct  784  KAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

127) ECBG_02263 in NC_020995


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  995 bits (3769),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 603/837 (73%), Positives = 694/837 (83%), Gaps = 42/837 (5%)

Query  3    YNHKEIEKKWQKYWAKKNEFNTHDEPDKPKFYALDMFPYPSGQGLHVGHPEGYTATDILS  62
            Y+H  IE KWQ +WA ++ F+T  ++ KPKFYALDMFPYPSG GLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RFKRSQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTKKNIETFRRQINALGFSYDWNR  122
            RFKR+QG NVLHPMGWDAFGLPAEQYA+DTGNDPAEFT  NI  F+RQINALGFSYDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EINTTDPEYYKWTQWIFTKLYEKGLAYEAEVPVNWVPELGTVIANEEVI-DGKSERGGYD  181
            E+NTTDP+YYKWTQWIFTKLYEKGLAYEAEVPVNWV ELGT IANEEV+ DG SERGGY 
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VIRKPMRQWMLKITAYADRLLDDLEEVDWPESIKEMQRNWIGRSVGANVTFKVAGMEKDF  241
            V+RKPMRQWMLKITAYA+RLL+DLEEVDWPESIK+MQRNWIG+S GANVTFKV + +KDF
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  TVFTTRPDTLFGATYAVLAPEHELVAQITTPEQKAAIDAYVEEASKKSDLNRTDLAKEKT  301
            TVFTTRPDTLFGATYAVLAPEH LV  ITT++Q  A+  Y  +AS KSDL RTDLAKEKT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAINPVNGKEIPIWIADYVLASYGTGAIMAVPAHDERDHEFAKTFGLEIIPVLA  361
            GV TG+YAINPVNGKE+P+WIADYVLASYGTGAIMAVPAHDERD EFAK F L+IIPVL 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGNVEESAYTEDGLHINSDFLDGLDKETAIEKMVAWLEENHVGKKEVSYRLRDWLFSRQR  421
            GGNVEE+A+TEDGLHINSDFLDGLDK +AI KMV WLE + VG+ +V+YRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPIIHWEDGTTTTLPEDQLPLRLPKTDNIKPSGTGESPLANVTDWVNVTDPETGK  481
            YWGEPIPIIHWEDGT+T++PE +LPL LP T +I+PSGTGESPLANVTDW++VT  E G 
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT-REDGV  482

Query  482  KGRRETNTMPQWAGSSWYFLRFIDPHNKSVLADYDKLKRWMPVDIYIGGAEHAVLHLLYA  541
            KGRRETNTMPQWAGSSWY+LR+IDPHN   LAD + LK+W+PVDIY+GGAEHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKFLYDIGVVPTKEPFEKLFNQGMILG------------------------------  571
            RFWHK LYD+GVVPTKEPF+KLFNQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---ENNEKMSKSRGNVVNPDDVINQYGADTLRLYEMFMGPLDASIAWNENGLEGSRKFLD  628
               +   KMSKS  NVVNPDDV++QYGADTLR+YEMFMGPLDASIAW+E+GLEGSRKFLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RVWRLIVDENGKMRDRITTFNDGKLSKVYHQTVKKVTEDFEQLHFNTAISQLMVFVNEAY  688
            RV RLI   +      IT  N G L KVY++TVK VTE+ +Q+ FNTAI+QLMVFVN A 
Sbjct  663  RVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  689  KADALPYEYVEGFVQLLAPIAPHIGEELWSIL-GNDHGISYVPWPTYDESALVEDEIEVV  747
            K D L  +Y  GFVQL+AP+APH+GEELW  L +++++ISYVPWP+YDES LVE+++E+V
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  748  FQVNGKVRAKAMVPADAEKAVLEQLAQENELVQEQLQGKTIRKVIVVPNKLVNIVAN  804
             Q++GKV+AK +V+ D  +  L+++A  NE VQ ++ GK I KVI VPNKLVNIV +
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

128) leuS in NC_015391


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  986 bits (3738),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 592/837 (71%), Positives = 688/837 (83%), Gaps = 41/837 (4%)

Query  14   FNHKTIEKKWQKYWASNNTFRTTEDAEKENFYALDMFPYPSGQGLHVGHPEGYTATDILS  73
            ++H +IE KWQ +WA N+TF+T  DA K +FYALDMFPYPSG GLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  74   RMKRAQGFNVLHPMGWDAFGLPAEQYALDTGNDPAEFTAHNIETFRRQINSLGFSYDWER  133
            R KRAQG NVLHPMGWDAFGLPAEQYA+DTGNDPAEFTA+NI  F+RQIN+LGFSYDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  134  EINTTDPDYYKWTQWIFTKLYEKGLAYEAEVAVNWCPALGTVLANEEVI-DGKSERGGHP  192
            E+NTTDP+YYKWTQWIFTKLYEKGLAYEAEV+VNW   LGT +ANEEV+ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  193  VYRKPMKQWMLKITVYADRLLDDLELVDWPESIKDMQRNWIGKSIGANVDFKVKGTDHKF  252
            V RKPM+QWMLKIT YA+RLL+DLE VDWPESIKDMQRNWIGKS GANV FKVK+TD  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  253  TVFTTRPDTLFGATYSVMAPELDLVKQITTPAQEAEVNAYIEKVSLKSDLDRTDLNKDKT  312
            TVFTTRPDTLFGATY+V+APE  LV  ITT+ Q   V  Y  + SLKSDL RTDL K+KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  313  GVFTGAYAINPVNGKEIPIWIADYVLASYGTGAIMAVPAHDERDYEFAKAFGLEIIPVLE  372
            GV TG+YAINPVNGKE+P+WIADYVLASYGTGAIMAVPAHDERD EFAK F L+IIPVLE
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  373  GGDVANAAFTEDGPHINSGFLDGLGKEEAIDKMNKWLEGNGVGKKETTYRLRDWLFARQR  432
            GG+V +AAFTEDG HINS+FLDGL+K  AI KM  WLE++GVG+ + TYRLRDWLF+RQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  433  YWGEPIPVIHWEDGTSTTLPESELPLILPKTDEIKPSGTGESPLANITEWVNVVDPETGM  492
            YWGEPIP+IHWEDGTST++PESELPL+LP T +I+PSGTGESPLAN+T+W++V   E G+
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT-REDGV  482

Query  493  KGRRDTNTMPQWAGSSWYFLRFIDPKNKEMLADPEKLKQWLPVDIYIGGAEHAVLHLLYA  552
            KGRR+TNTMPQWAGSSWY+LR+IDP N E LAD E LKQWLPVDIY+GGAEHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  553  RFWHKFLYDIGVVPTKEPFQKLYNQGMILGGN----------------------------  584
            RFWHK LYD+GVVPTKEPFQKL+NQGMILG +                            
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  585  -----NEKMSKSKGNVVNPDDVVEKFGADTLRMYEMFMGPLDASIAWSENGLEGSRKFLD  639
                   KMSKS  NVVNPDDVVE++GADTLR+YEMFMGPLDASIAWSE+GLEGSRKFLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  640  RVWRLIMDENGKVRDRITKFNDGSLDVVYHQTVKKVTEDFEHLRFNTAISQMMVFVNEAY  699
            RV RLI   +      IT  N G+LD VY++TVK VTE+ ++++FNTAI+Q+MVFVN A 
Sbjct  663  RVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  700  KATALPVDYIKAFVQLLAPIAPHMGEELWANLTHSGESISYVTWPTFDEKFLVEDEIEVV  759
            K   L  DY K+FVQL+AP+APH+GEELW  LT SGESISYV WP++DE  LVE+++E+V
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  760  FQVNGKLKAKAQASKEISREDLETLAMNNEKIKEAIEGKTIRKVIVVPGRLVNIVAN  816
             Q++GK+KAK   +K++SRE+L+ +A+ NEK++  I GK I KVI VP +LVNIV +
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

129) leuS in NC_004668


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  981 bits (3716),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 593/837 (71%), Positives = 694/837 (83%), Gaps = 42/837 (5%)

Query  3    YNHKEIEKKWQKYWAKNNCFNTLDDPNKEKFYALDMFPYPSGQGLHVGHPEGYTATDILS  62
            Y+H  IE KWQ +WA N+ F+T  D++K KFYALDMFPYPSG GLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMKRAQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTKKNIETFRRQINSLGFSYDWNR  122
            R KRAQG NVLHPMGWDAFGLPAEQYA+DTGNDPAEFT  NI  F+RQIN+LGFSYDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EINTTDPEYYKWTQWIFTKLYEKGLAYEAEVAVNWVPELGTVISNEEVI-DGKSERGGYD  181
            E+NTTDP+YYKWTQWIFTKLYEKGLAYEAEV+VNWV ELGT I+NEEV+ DG SERGGY 
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VVRRPMRQWMLKITAYADRLLEDLELVDWPESIKDMQRNWIGRSEGANVTFKVAGTEESF  241
            VVR+PMRQWMLKITAYA+RLLEDLE VDWPESIKDMQRNWIG+S GANVTFKV +T+  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  TVFTTRPDTLFGATYTVLAPELELVKKITTPEQTAAVEAYIEETSKKSDLNRTDLAKEKT  301
            TVFTTRPDTLFGATY+VLAPE  LV  ITT++Q+ AV  Y  ++S KSDL RTDLAKEKT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAINPVNGQEIPIWIGDYVLASYGTGAIMAVPAHDERDYEFAKTFGIDILPVIA  361
            GV TG+YAINPVNG+E+P+WI+DYVLASYGTGAIMAVPAHDERD EFAK F +DI+PV+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGDITTEAYTGDGPHINSDFLNGLNKAEAIAKMNEWLEENHVGKKEVSYRLRDWLFSRQR  421
            GG++   A+T DG HINSDFL+GL+KA AIAKM EWLE + VG+ +V+YRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPVIHWEDGTTTTVPESELPLRLPVTSDIRPSGTGESPLANIDEWVNVVDPETGM  481
            YWGEPIP+IHWEDGT+T+VPESELPL LPVT DIRPSGTGESPLAN+ +W++V   E G+
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT-REDGV  482

Query  482  KGKRETNTMPQWAGSSWYYLRFIDPHNKNEIADFEKLKRWLPVDIYIGGAEHAVLHLLYA  541
            KG+RETNTMPQWAGSSWYYLR+IDPHN + +AD E LK+WLPVDIY+GGAEHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKFLYDIGVVPTKEPFQKLYNQGMILG------------------------------  571
            RFWHK LYD+GVVPTKEPFQKL+NQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---ENNEKMSKSRGNVVNPDDVVAKYGADTLRLYEMFMGPLDASIAWNENGLEGSRKFLD  628
               +   KMSKS  NVVNPDDVV +YGADTLR+YEMFMGPLDASIAW+E+GLEGSRKFLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RVWRLIVDEEGKMRDRITTINDGRLTKVYHQTVKKVTEDMANLHFNTAISQLMVFVNEAN  688
            RV RLI   E      IT  N G L KVY++TVK VTE++ ++ FNTAI+QLMVFVN AN
Sbjct  663  RVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  689  KVDALPYEYVEGFVQLLAPIAPHIGEELWQIL-GNEESLTYVPWPTYDETALVEDEVEVV  747
            K D L  +Y  GFVQL+AP+APH+GEELWQ L ++ ES++YVPWP+YDE+ LVE++VE+V
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  748  FQVNGKLRGKQNVARGLSKEELEQIAMNHEAVKEFIEGKTVRKVIAVPDKLVNIVAN  804
             Q++GK+++K  VA++LS+EEL+++A+ +E V+  I GK + KVIAVP+KLVNIV +
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

130) leuS in NC_019770


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  963 bits (3650),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 593/837 (71%), Positives = 695/837 (84%), Gaps = 42/837 (5%)

Query  3    YNHKEIEKKWQKYWAKNNCFNTLDDPNKEKFYALDMFPYPSGQGLHVGHPEGYTATDILS  62
            Y+H  IE KWQ +WA N+ F+T  D++K KFYALDMFPYPSG GLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMKRAQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTKKNIETFRRQINSLGFSYDWNR  122
            R KRAQG NVLHPMGWDAFGLPAEQYA+DTGNDPAEFT  NI  F+RQIN+LGFSYDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EINTTDPEYYKWTQWIFTKLYEKGLAYEAEVAVNWVPELGTVISNEEVI-DGKSERGGYD  181
            E+NTTDP+YYKWTQWIFTKLYEKGLAYEAEV+VNWV ELGT I+NEEV+ DG SERGGY 
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VVRRPMRQWMLKITAYADRLLEDLELVDWPESIKDMQRNWIGRSEGANVTFKVAGTEESF  241
            VVR+PMRQWMLKITAYA+RLLEDLE VDWPESIKDMQRNWIG+S GANVTFKV +T+  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  TVFTTRPDTLFGATYTVLAPELELVKKITTPEQTAAVEAYIKETSKKSDLNRTDLAKEKT  301
            TVFTTRPDTLFGATY+VLAPE  LV  ITT++Q+ AV  Y +++S KSDL RTDLAKEKT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAINPVNGQEIPIWIGDYVLASYGTGAIMAVPAHDERDYEFAKTFGIDILPVIA  361
            GV TG+YAINPVNG+E+P+WI+DYVLASYGTGAIMAVPAHDERD EFAK F +DI+PV+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGDITTEAYTGDGPHINSDFLNGLNKAEAIAKMNEWLEENHVGKKEVSYRLRDWLFSRQR  421
            GG++   A+T DG HINSDFL+GL+KA AIAKM EWLE + VG+ +V+YRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPVIHWEDGTTTTVPESELPLRLPVTSDIRPSGTGESPLANIDEWVNVVDPETGM  481
            YWGEPIP+IHWEDGT+T+VPESELPL LPVT DIRPSGTGESPLAN+ +W++V   E G+
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT-REDGV  482

Query  482  KGKRETNTMPQWAGSSWYYLRFIDPHNKNEIADFEKLKRWLPVDIYIGGAEHAVLHLLYA  541
            KG+RETNTMPQWAGSSWYYLR+IDPHN + +AD E LK+WLPVDIY+GGAEHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKFLYDIGVVPTKEPFQKLYNQGMILG------------------------------  571
            RFWHK LYD+GVVPTKEPFQKL+NQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---ENNEKMSKSRGNVVNPDDVVAKYGADTLRLYEMFMGPLDASIAWNENGLEGSRKFLD  628
               +   KMSKS  NVVNPDDVV +YGADTLR+YEMFMGPLDASIAW+E+GLEGSRKFLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RVWRLIVDEEGKMRDRITTINDGRLTKVYHQTVKKVTEDMANLHFNTAISQLMVFVNEAN  688
            RV RLI   E      IT  N G L KVY++TVK VTE++ ++ FNTAI+QLMVFVN AN
Sbjct  663  RVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  689  KVDALPYEYVEGFVQLLAPIAPHIGEELWQIL-GNEESLTYVPWPTYdeaalvedevevv  747
            K D L  +Y  GFVQL+AP+APH+GEELWQ L ++ ES++YVPWP+YDE+ LVE++VE+V
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  748  FQVNGKLRGKQNVARGLSKEELEQIAMNHEAVKEFIEGKTVRKVIAVPDKLVNIVAN  804
             Q++GK+++K  VA++LS+EEL+++A+ +E V+  I GK + KVIAVP+KLVNIV +
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

131) leuS in NC_003212


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  963 bits (3649),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 566/836 (68%), Positives = 692/836 (83%), Gaps = 41/836 (4%)

Query  3    FNHKKMEPKWQQYWSEHNTFKTTEDKDKENFYALDMFPYPSGAGLHVGHPEGYTATDILS  62
            ++H  +EPKWQ +W++++TFKT  D  K +FYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMKRMQGKNVLHPIGWDAFGLPAEQYAIDTGNDPEEFTALNIANFTRQIKSLGFSYDWDR  122
            R KR QG NVLHP+GWDAFGLPAEQYA+DTGNDP EFTA NIANF RQI++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EINTTDPEYYKWTQWIFEKLYENGLAYEAEIAVNWCPALGTVLANEEVI-DGKSERGGFP  181
            E+NTTDP+YYKWTQWIF KLYE+GLAYEAE++VNW   LGT +ANEEV+ DG SERGG+P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VFRKPMRQWMLKITAYADRLLDDLELVDWPENIKDMQRNWIGRSEGAEVTFKIKDSDETF  241
            V RKPMRQWMLKITAYA+RLL+DLE VDWPE+IKDMQRNWIG+S GA+VTFK+KD+D  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  NVFTTRPDTLFGATYTVFAPEHELIEKITTPEQKEAVEAYKKQVELKSELERTDLAKDKT  301
             VFTTRPDTLFGATY+V+APEH L++ ITT++Q EAV  YK+Q  LKS+L RTDLAK+KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAINPINGEEVPIWIADYVLIQYGTGAIMAVPAHDERDFEFAQQFGLNIRPVLE  361
            GV TG+YAINP+NG E+P+WIADYVL  YGTGAIMAVPAHDERD EFA+QF L+I PVLE
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGDVTKEAFTGDGPHINSDFLNGLAKAEAITAAIDWLEKEGIGSRKITYRLRDWLFSRQR  421
            GG+V   AFT DG HINSDFL+GL KA AI+  ++WLE EG+G+ ++TYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPVIHWEDGettlvpedelplllpKATEIKPSGTGESPLANLHDWVNVTDENGRK  481
            YWGEPIP+IHWEDG +T VPE ELPL+LP + +I+PSGTGESPLAN+ DW++VT E+G K
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  482  GRRETNTMPQWAGSSWYFLRYIDPKNSEAIADKEKLAEWLPVDVYIGGAEHAVLHLLYAR  541
            GRRETNTMPQWAGSSWY+LRYIDP N+E +AD E L +WLPVD+Y+GGAEHAVLHLLYAR
Sbjct  484  GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYAR  543

Query  542  FWHKFLYDIGVVPTKEPFQKLFNQGMILG-------------------------------  570
            FWHK LYD+GVVPTKEPFQKLFNQGMILG                               
Sbjct  544  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEE  603

Query  571  --ENNEKMSKSRGNVVNPDEVVEKYGADTLRLYEMFMGPLEASIAWNENGLEGARKFLDR  628
              +   KMSKS  NVVNPD+VVE+YGADTLR+YEMFMGPL+ASIAW+E+GLEG+RKFLDR
Sbjct  604  LEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR  663

Query  629  IWRLLVTEEGTLAEKVTTDANANLEKAYHHMVKTVTNHYENLRFNTGISQLMIFINEAYK  688
            + RL+ T E      +T + ++ L+K Y++ VK+VT++ ++++FNT+I+QLM+F+N A K
Sbjct  664  VYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANK  717

Query  689  RDTIPKQYVEGFVQLLSPIAPHLAEELWEIL-GHTETISYVAWPTYDETKLVEDEVEIVL  747
             D +  +Y  GFVQL++P+APHL+EELW+ L +  E+ISYV+WP+YDE+KLVE++VEIV+
Sbjct  718  EDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVV  777

Query  748  QVNGKVKSKITVAKSLGKEELEKLAHEDDKIKENIDGKTIRKVIVVPGKLVNIVAN  803
            Q++GKVK+K+ VAK L++EEL+ +A  ++K++ +I GK I KVI VP KLVNIV +
Sbjct  778  QIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

132) leuS in NC_021994


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  962 bits (3645),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 599/837 (72%), Positives = 686/837 (82%), Gaps = 42/837 (5%)

Query  3    YNHKEIEKKWQKYWAKTNTFNTHDDPEKPKFYALDMFPYPSGQGLHVGHPEGYTATDILS  62
            Y+H  IE KWQ +WA  +TF+T  D+ KPKFYALDMFPYPSG GLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RVKRSQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTQKNIETFRRQINSLGFSYDWNR  122
            R KR+QG NVLHPMGWDAFGLPAEQYA+DTGNDPAEFT  NI  F+RQIN+LGFSYDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVNTTDPEYYKWTQWIFTKLYEKGLAYEAEVAVNWVPELGTVISNEEVI-DGKSERGGYD  181
            EVNTTDP+YYKWTQWIFTKLYEKGLAYEAEV+VNWV ELGT I+NEEV+ DG SERGGY 
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VVRKPMRQWMLKITAYADRLLDDLELVDWPESIKEMQRNWIGRSVGANIEFKVAGTDKSY  241
            VVRKPMRQWMLKITAYA+RLL+DLE VDWPESIK+MQRNWIG+S GAN+ FKV +TDK +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  TVFTTRPDTLFGATYSVLAPELDLVREITTPEQKAAVEAYIEETAKKSDLKRTDLAKEKT  301
            TVFTTRPDTLFGATY+VLAPE  LV  ITT++Q  AV  Y  +++ KSDL RTDLAKEKT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAINPVNGKEIPIWIADYVLSSYGTGAIMAVPAHDERDFEFAQTFGLEILPVIE  361
            GV TG+YAINPVNGKE+P+WIADYVL+SYGTGAIMAVPAHDERD EFA+ F L+I+PV+E
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGDVEKAAYTEDGTHINSEFLDGMNKQEAIDKMNEWLEENGVGKKEVSYRLRDWLFSRQR  421
            GG+VE AA+TEDG HINS+FLDG++K  AI KM EWLE +GVG+ +V+YRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPIIHWEDGTVTAVPEEELPLRLPKTKNIKPSGTGESPLANIEEWVNVVDPVTGK  481
            YWGEPIPIIHWEDGT TAVPE ELPL LP TK+I+PSGTGESPLAN+ +W++V     G 
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRE-DGV  482

Query  482  KGRRETNTMPQWAGSSWYYLRYIDPHNKKELADYEKLKRWLPVDIYIGGAEHAVLHLLYA  541
            KGRRETNTMPQWAGSSWYYLRYIDPHN   LAD E LK+WLPVDIY+GGAEHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKFLYDIGVVPTKEPFQKLYNQGMILG------------------------------  571
            RFWHK LYD+GVVPTKEPFQKL+NQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---ENNEKMSKSRGNVVNPDDVVETYGADTLRMYEMFMGPLDASIAWSENGLEGSRKFLD  628
               +   KMSKS  NVVNPDDVVE YGADTLR+YEMFMGPLDASIAWSE+GLEGSRKFLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RVWRLIVDENNKMRDRITTLNDGKLDKVYHQTVKKVTEDYENLHFNTAISQLMVFINEAY  688
            RV RLI   +      IT  N G LDKVY++TVK VTE+ +++ FNTAI+QLMVF+N A 
Sbjct  663  RVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  689  KVDALPYEYIEGFVQLLAPIAPHMGEELWAILGNDG-GISYAPWPTYdeaalvedevevv  747
            K D L  +Y  GFVQL+AP+APH+GEELW  L   G +ISY PWP+YDE+ LVE++VE+V
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  748  FQVNGKVRAKSNVPRDLGKDELEKAALANEIVQEYIEGKTVRKVIAVPNKLVNIVAN  804
             Q++GKV+AK  V++DL+++EL+  ALANE VQ  I GK + KVIAVPNKLVNIV +
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

133) leuS in NC_017960


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  962 bits (3645),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 599/837 (72%), Positives = 686/837 (82%), Gaps = 42/837 (5%)

Query  3    YNHKEIEKKWQKYWAKTNTFNTHDDPEKPKFYALDMFPYPSGQGLHVGHPEGYTATDILS  62
            Y+H  IE KWQ +WA  +TF+T  D+ KPKFYALDMFPYPSG GLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RVKRSQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTQKNIETFRRQINSLGFSYDWNR  122
            R KR+QG NVLHPMGWDAFGLPAEQYA+DTGNDPAEFT  NI  F+RQIN+LGFSYDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVNTTDPEYYKWTQWIFTKLYEKGLAYEAEVAVNWVPELGTVISNEEVI-DGKSERGGYD  181
            EVNTTDP+YYKWTQWIFTKLYEKGLAYEAEV+VNWV ELGT I+NEEV+ DG SERGGY 
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VVRKPMRQWMLKITAYADRLLDDLELVDWPESIKEMQRNWIGRSVGANIEFKVAGTDKSY  241
            VVRKPMRQWMLKITAYA+RLL+DLE VDWPESIK+MQRNWIG+S GAN+ FKV +TDK +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  TVFTTRPDTLFGATYSVLAPELDLVREITTPEQKAAVEAYIEETAKKSDLKRTDLAKEKT  301
            TVFTTRPDTLFGATY+VLAPE  LV  ITT++Q  AV  Y  +++ KSDL RTDLAKEKT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAINPVNGKEIPIWIADYVLSSYGTGAIMAVPAHDERDFEFAQTFGLEILPVIE  361
            GV TG+YAINPVNGKE+P+WIADYVL+SYGTGAIMAVPAHDERD EFA+ F L+I+PV+E
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGDVEKAAYTEDGTHINSEFLDGMNKQEAIDKMNEWLEENGVGKKEVSYRLRDWLFSRQR  421
            GG+VE AA+TEDG HINS+FLDG++K  AI KM EWLE +GVG+ +V+YRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPIIHWEDGTVTAVPEEELPLRLPKTKNIKPSGTGESPLANIEEWVNVVDPVTGK  481
            YWGEPIPIIHWEDGT TAVPE ELPL LP TK+I+PSGTGESPLAN+ +W++V     G 
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRE-DGV  482

Query  482  KGRRETNTMPQWAGSSWYYLRYIDPHNKKELADYEKLKRWLPVDIYIGGAEHAVLHLLYA  541
            KGRRETNTMPQWAGSSWYYLRYIDPHN   LAD E LK+WLPVDIY+GGAEHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKFLYDIGVVPTKEPFQKLYNQGMILG------------------------------  571
            RFWHK LYD+GVVPTKEPFQKL+NQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---ENNEKMSKSRGNVVNPDDVVETYGADTLRMYEMFMGPLDASIAWSENGLEGSRKFLD  628
               +   KMSKS  NVVNPDDVVE YGADTLR+YEMFMGPLDASIAWSE+GLEGSRKFLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RVWRLIVDENNKMRDRITTLNDGKLDKVYHQTVKKVTEDYENLHFNTAISQLMVFINEAY  688
            RV RLI   +      IT  N G LDKVY++TVK VTE+ +++ FNTAI+QLMVF+N A 
Sbjct  663  RVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  689  KVDALPYEYIEGFVQLLAPIAPHMGEELWAILGNDG-GISYAPWPTYdeaalvedevevv  747
            K D L  +Y  GFVQL+AP+APH+GEELW  L   G +ISY PWP+YDE+ LVE++VE+V
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  748  FQVNGKVRAKSNVPRDLGKDELEKAALANEIVQEYIEGKTVRKVIAVPNKLVNIVAN  804
             Q++GKV+AK  V++DL+++EL+  ALANE VQ  I GK + KVIAVPNKLVNIV +
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

134) M7W_2542 in NC_020207


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  962 bits (3645),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 599/837 (72%), Positives = 686/837 (82%), Gaps = 42/837 (5%)

Query  3    YNHKEIEKKWQKYWAKTNTFNTHDDPEKPKFYALDMFPYPSGQGLHVGHPEGYTATDILS  62
            Y+H  IE KWQ +WA  +TF+T  D+ KPKFYALDMFPYPSG GLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RVKRSQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTQKNIETFRRQINSLGFSYDWNR  122
            R KR+QG NVLHPMGWDAFGLPAEQYA+DTGNDPAEFT  NI  F+RQIN+LGFSYDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVNTTDPEYYKWTQWIFTKLYEKGLAYEAEVAVNWVPELGTVISNEEVI-DGKSERGGYD  181
            EVNTTDP+YYKWTQWIFTKLYEKGLAYEAEV+VNWV ELGT I+NEEV+ DG SERGGY 
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VVRKPMRQWMLKITAYADRLLDDLELVDWPESIKEMQRNWIGRSVGANIEFKVAGTDKSY  241
            VVRKPMRQWMLKITAYA+RLL+DLE VDWPESIK+MQRNWIG+S GAN+ FKV +TDK +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  TVFTTRPDTLFGATYSVLAPELDLVREITTPEQKAAVEAYIEETAKKSDLKRTDLAKEKT  301
            TVFTTRPDTLFGATY+VLAPE  LV  ITT++Q  AV  Y  +++ KSDL RTDLAKEKT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAINPVNGKEIPIWIADYVLSSYGTGAIMAVPAHDERDFEFAQTFGLEILPVIE  361
            GV TG+YAINPVNGKE+P+WIADYVL+SYGTGAIMAVPAHDERD EFA+ F L+I+PV+E
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGDVEKAAYTEDGTHINSEFLDGMNKQEAIDKMNEWLEENGVGKKEVSYRLRDWLFSRQR  421
            GG+VE AA+TEDG HINS+FLDG++K  AI KM EWLE +GVG+ +V+YRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPIIHWEDGTVTAVPEEELPLRLPKTKNIKPSGTGESPLANIEEWVNVVDPVTGK  481
            YWGEPIPIIHWEDGT TAVPE ELPL LP TK+I+PSGTGESPLAN+ +W++V     G 
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRE-DGV  482

Query  482  KGRRETNTMPQWAGSSWYYLRYIDPHNKKELADYEKLKRWLPVDIYIGGAEHAVLHLLYA  541
            KGRRETNTMPQWAGSSWYYLRYIDPHN   LAD E LK+WLPVDIY+GGAEHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKFLYDIGVVPTKEPFQKLYNQGMILG------------------------------  571
            RFWHK LYD+GVVPTKEPFQKL+NQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---ENNEKMSKSRGNVVNPDDVVETYGADTLRMYEMFMGPLDASIAWSENGLEGSRKFLD  628
               +   KMSKS  NVVNPDDVVE YGADTLR+YEMFMGPLDASIAWSE+GLEGSRKFLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RVWRLIVDENNKMRDRITTLNDGKLDKVYHQTVKKVTEDYENLHFNTAISQLMVFINEAY  688
            RV RLI   +      IT  N G LDKVY++TVK VTE+ +++ FNTAI+QLMVF+N A 
Sbjct  663  RVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  689  KVDALPYEYIEGFVQLLAPIAPHMGEELWAILGNDG-GISYAPWPTYdeaalvedevevv  747
            K D L  +Y  GFVQL+AP+APH+GEELW  L   G +ISY PWP+YDE+ LVE++VE+V
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  748  FQVNGKVRAKSNVPRDLGKDELEKAALANEIVQEYIEGKTVRKVIAVPNKLVNIVAN  804
             Q++GKV+AK  V++DL+++EL+  ALANE VQ  I GK + KVIAVPNKLVNIV +
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

135) ENT_22930 in NC_021023


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  962 bits (3644),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 593/837 (71%), Positives = 694/837 (83%), Gaps = 42/837 (5%)

Query  3    YNHKEIEKKWQKYWAKNNCFNTLDDPNKEKFYALDMFPYPSGQGLHVGHPEGYTATDILS  62
            Y+H  IE KWQ +WA N+ F+T  D++K KFYALDMFPYPSG GLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMKRAQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTKKNIETFRRQINSLGFSYDWNR  122
            R KRAQG NVLHPMGWDAFGLPAEQYA+DTGNDPAEFT  NI  F+RQIN+LGFSYDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EINTTDPEYYKWTQWIFTKLYEKGLAYEAEVAVNWVPELGTVISNEEVI-DGKSERGGYD  181
            E+NTTDP+YYKWTQWIFTKLYEKGLAYEAEV+VNWV ELGT I+NEEV+ DG SERGGY 
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VVRRPMRQWMLKITAYADRLLEDLELVDWPESIKDMQRNWIGRSEGANVTFKVAGTEESF  241
            VVR+PMRQWMLKITAYA+RLLEDLE VDWPESIKDMQRNWIG+S GANVTFKV +T+  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  TVFTTRPDTLFGATYTVLAPELELVKKITTPEQTAAVEAYIEETSKKSDLNRTDLAKEKT  301
            TVFTTRPDTLFGATY+VLAPE  LV  ITT++Q+ AV  Y  ++S KSDL RTDLAKEKT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAINPVNGQEIPIWIGDYVLASYGTGAIMAVPAHDERDYEFAKTFGIDILPVIA  361
            GV TG+YAINPVNG+E+P+WI+DYVLASYGTGAIMAVPAHDERD EFAK F +DI+PV+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGDITTEAYTGDGPHINSDFLNGLNKAEAIAKMNEWLEENHVGKKEVSYRLRDWLFSRQR  421
            GG++   A+T DG HINSDFL+GL+KA AIAKM EWLE + VG+ +V+YRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPVIHWEDGTTTTVPESELPLRLPVTSDIRPSGTGESPLANIDEWVNVVDPETGM  481
            YWGEPIP+IHWEDGT+T+VPESELPL LPVT DIRPSGTGESPLAN+ +W++V   E G+
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT-REDGV  482

Query  482  KGKRETNTMPQWAGSSWYYLRFIDPHNKNEIADFEKLKRWLPVDIYIGGAEHAVLHLLYA  541
            KG+RETNTMPQWAGSSWYYLR+IDPHN + +AD E LK+WLPVDIY+GGAEHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKFLYDIGVVPTKEPFQKLYNQGMILG------------------------------  571
            RFWHK LYD+GVVPTKEPFQKL+NQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---ENNEKMSKSRGNVVNPDDVVAKYGADTLRLYEMFMGPLDASIAWNENGLEGSRKFLD  628
               +   KMSKS  NVVNPDDVV +YGADTLR+YEMFMGPLDASIAW+E+GLEGSRKFLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RVWRLIVDEEGKMRDRITTINDGRLTKVYHQTVKKVTEDMANLHFNTAISQLMVFVNEAN  688
            RV RLI   E      IT  N G L KVY++TVK VTE++ ++ FNTAI+QLMVFVN AN
Sbjct  663  RVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  689  KVDALPYEYVEGFVQLLAPIAPHIGEELWQIL-GNEESLTYVPWPTYdeaalvedevevv  747
            K D L  +Y  GFVQL+AP+APH+GEELWQ L ++ ES++YVPWP+YDE+ LVE++VE+V
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  748  FQVNGKLRGKQNVARGLSKEELEQIAMNHEAVKEFIEGKTVRKVIAVPDKLVNIVAN  804
             Q++GK+++K  VA++LS+EEL+++A+ +E V+  I GK + KVIAVP+KLVNIV +
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

136) MPD5_0393 in NC_016938


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  962 bits (3645),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 573/837 (69%), Positives = 678/837 (82%), Gaps = 42/837 (5%)

Query  3    YDHKKIEKKWQNYWAMNNTFITKEEPDREKFYALDMFPYPSGKGLHVGHPEGYTATDILS  62
            YDH  IE KWQ +WA N+TF T  ++ + KFYALDMFPYPSG GLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMKRSQGYNVLHPMGWDAFGLPAEQYALDTGNDPEVFTKENIETFKRQINSLGFSYDWNR  122
            R KR+QG NVLHPMGWDAFGLPAEQYA+DTGNDP  FT ENI  FKRQIN+LGFSYDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EISTTNPDYYKWTQWIFTKLYEKGLAYEAEVAVNWVPELGTVISNEEVI-DGKSERGGYD  181
            E++TT+P+YYKWTQWIFTKLYEKGLAYEAEV+VNWV ELGT I+NEEV+ DG SERGGY 
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VIRKPMRQWMLKITAYADRLLKDLDLVDWPENIKDMQRNWIGRSEGANITFQVAGIEQAF  241
            V+RKPMRQWMLKITAYA+RLL DL+ VDWPE+IKDMQRNWIG+S GAN+TF+V + ++ F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  TVFTTRADTLFGATYTVLAPEHKLVKEITTPKQQKMVEKYVAEAAKKSDLMRTELAKEKT  301
            TVFTTR+DTLFGATY+VLAPEH LV  ITT+ Q   V  Y  +A+ KSDL RT+LAKEKT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAINPVNNKKIPIWISDYVLSSYGTGAIMAVPAHDERDYAFAKTFNLEILPVID  361
            GV TG+YAINPVN K +P+WI+DYVL+SYGTGAIMAVPAHDERD  FAK FNL+I+PV++
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGNVEEEAYTGNGRHINSGFLDGLDKETAISTMIDWLEEHKVGEKKVSYRLRDWLFSRQR  421
            GGNVEE A+T +G HINS+FLDGLDK +AI+ M++WLE + VG+ +V+YRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPIIHWEDGTTSVVPESELPLCLPKVTDIHPSGTGESPLANIEDWINVIDPKTGK  481
            YWGEPIPIIHWEDGT++ VPESELPL LP   DI+PSGTGESPLAN+ DW++V     G 
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT-REDGV  482

Query  482  KGKRETNTMPQWAGSSWYYLRFIDPYNKEKIASYEALERWLPVDIYIGGAEHAVLHLLYA  541
            KG+RETNTMPQWAGSSWYYLR+IDP N EK+A  E L +WLPVDIY+GGAEHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKFLYDLGVVPTKEPFQKLYNQGMILG------------------------------  571
            RFWHK LYDLGVVPTKEPFQKL+NQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---KNNEKMSKSRGNVVNPDDVIEKYGADTLRLYEMFMGPLDASIAWSENGLEGSRKFLD  628
               +   KMSKS  NVVNPDDV+E+YGADTLR+YEMFMGPLDASIAWSE+GLEGSRKFLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RVWRLLVSETGTMNARIIKTNDGQLTKLYNQTVKKVTEDLEAMHFNTAISQLMIFVNEAN  688
            RV RL+ +        I   N G L K+YN+TVK VTE+++ M FNTAI+QLM+FVN AN
Sbjct  663  RVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  689  KIAELPYNYALGFVQLLAPIVPHLGEELWEIL-GKTDSISYAPWPEYDESVLVEEETEII  747
            K   L  +YA GFVQL+AP+ PHLGEELW+ L +  +SISY PWP YDES LVE++ EI+
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  748  FQVNGKVRGKMTLPKGLGKEELEQKALTIESIQRILEGKNIHKVIVIPDKLVNIVAK  804
             Q++GKV++K+ ++K+L++EEL++ AL+ E +Q  + GK+I KVI +P+KLVNIV K
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

137) leuS in NC_017022


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  961 bits (3642),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 599/837 (72%), Positives = 686/837 (82%), Gaps = 42/837 (5%)

Query  3    YNHKEIEKKWQKYWAKTNTFNTHDDPEKPKFYALDMFPYPSGQGLHVGHPEGYTATDILS  62
            Y+H  IE KWQ +WA  +TF+T  D+ KPKFYALDMFPYPSG GLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RVKRSQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTQKNIETFRRQINSLGFSYDWNR  122
            R KR+QG NVLHPMGWDAFGLPAEQYA+DTGNDPAEFT  NI  F+RQIN+LGFSYDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVNTTDPEYYKWTQWIFTKLYEKGLAYEAEVAVNWVPELGTVISNEEVI-DGKSERGGYD  181
            EVNTTDP+YYKWTQWIFTKLYEKGLAYEAEV+VNWV ELGT I+NEEV+ DG SERGGY 
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VVRKPMRQWMLKITAYADRLLDDLELVDWPESIKEMQRNWIGRSVGANIEFKVAGTDKSY  241
            VVRKPMRQWMLKITAYA+RLL+DLE VDWPESIK+MQRNWIG+S GAN+ FKV +TDK +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  TVFTTRPDTLFGATYSVLAPELDLVREITTPEQKAAVEAYIEETAKKSDLKRTDLAKEKT  301
            TVFTTRPDTLFGATY+VLAPE  LV  ITT++Q  AV  Y  +++ KSDL RTDLAKEKT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAINPVNGKEIPIWIADYVLSSYGTGAIMAVPAHDERDFEFAQTFGLEILPVIE  361
            GV TG+YAINPVNGKE+P+WIADYVL+SYGTGAIMAVPAHDERD EFA+ F L+I+PV+E
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGDVEKAAYTEDGTHINSEFLDGMNKQEAIDKMNEWLEKNGVGKKEVSYRLRDWLFSRQR  421
            GG+VE AA+TEDG HINS+FLDG++K  AI KM EWLE +GVG+ +V+YRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPIIHWEDGTVTAVPEEELPLRLPKTKNIKPSGTGESPLANIEEWVNVVDPVTGK  481
            YWGEPIPIIHWEDGT TAVPE ELPL LP TK+I+PSGTGESPLAN+ +W++V     G 
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRE-DGV  482

Query  482  KGRRETNTMPQWAGSSWYYLRYIDPHNKKELADYEKLKRWLPVDIYIGGAEHAVLHLLYA  541
            KGRRETNTMPQWAGSSWYYLRYIDPHN   LAD E LK+WLPVDIY+GGAEHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKFLYDIGVVPTKEPFQKLYNQGMILG------------------------------  571
            RFWHK LYD+GVVPTKEPFQKL+NQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---ENNEKMSKSRGNVVNPDDVVETYGADTLRMYEMFMGPLDASIAWSENGLEGSRKFLD  628
               +   KMSKS  NVVNPDDVVE YGADTLR+YEMFMGPLDASIAWSE+GLEGSRKFLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RVWRLIVDENNKMRDRITTLNDGKLDKVYHQTVKKVTEDYENLHFNTAISQLMVFINEAY  688
            RV RLI   +      IT  N G LDKVY++TVK VTE+ +++ FNTAI+QLMVF+N A 
Sbjct  663  RVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  689  KVDALPYEYIEGFVQLLAPIAPHMGEELWAILGNDG-GISYAPWPTYdeaalvedevevv  747
            K D L  +Y  GFVQL+AP+APH+GEELW  L   G +ISY PWP+YDE+ LVE++VE+V
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  748  FQVNGKVRAKSNVPRDLGKDELEKAALANEIVQEYIEGKTVRKVIAVPNKLVNIVAN  804
             Q++GKV+AK  V++DL+++EL+  ALANE VQ  I GK + KVIAVPNKLVNIV +
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

138) EFD32_0611 in NC_018221


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  961 bits (3643),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 592/837 (71%), Positives = 694/837 (83%), Gaps = 42/837 (5%)

Query  3    YNHKEIEKKWQKYWAKNNCFNTLDDPNKEKFYALDMFPYPSGQGLHVGHPEGYTATDILS  62
            Y+H  IE KWQ +WA N+ F+T  D++K KFYALDMFPYPSG GLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMKRAQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTKKNIETFRRQINSLGFSYDWNR  122
            R KRAQG NVLHPMGWDAFGLPAEQYA+DTGNDPAEFT  NI  F+RQIN+LGFSYDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EINTTDPEYYKWTQWIFTKLYEKGLAYEAEVAVNWVPELGTVISNEEVI-DGKSERGGYD  181
            E+NTTDP+YYKWTQWIFTKLYEKGLAYEAEV+VNWV ELGT I+NEEV+ DG SERGGY 
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VVRRPMRQWMLKITAYADRLLEDLELVDWPESIKDMQRNWIGRSEGANVTFKVAGTEESF  241
            VVR+PMRQWMLKITAYA+RLLEDLE VDWPESIKDMQRNWIG+S GANVTFKV +T+  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  TVFTTRPDTLFGATYTVLAPELELVKKITTPEQTASVEAYIEETSKKSDLNRTDLAKEKT  301
            TVFTTRPDTLFGATY+VLAPE  LV  ITT++Q+ +V  Y  ++S KSDL RTDLAKEKT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAINPVNGQEIPIWIGDYVLASYGTGAIMAVPAHDERDYEFAKTFGIDILPVIA  361
            GV TG+YAINPVNG+E+P+WI+DYVLASYGTGAIMAVPAHDERD EFAK F +DI+PV+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGDITTEAYTGDGPHINSDFLNGLNKAEAIAKMNEWLEENHVGKKEVSYRLRDWLFSRQR  421
            GG++   A+T DG HINSDFL+GL+KA AIAKM EWLE + VG+ +V+YRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPVIHWEDGTTTTVPESELPLRLPVTSDIRPSGTGESPLANIDEWVNVVDPETGM  481
            YWGEPIP+IHWEDGT+T+VPESELPL LPVT DIRPSGTGESPLAN+ +W++V   E G+
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT-REDGV  482

Query  482  KGKRETNTMPQWAGSSWYYLRFIDPHNKNEIADFEKLKRWLPVDIYIGGAEHAVLHLLYA  541
            KG+RETNTMPQWAGSSWYYLR+IDPHN + +AD E LK+WLPVDIY+GGAEHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKFLYDIGVVPTKEPFQKLYNQGMILG------------------------------  571
            RFWHK LYD+GVVPTKEPFQKL+NQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---ENNEKMSKSRGNVVNPDDVVAKYGADTLRLYEMFMGPLDASIAWNENGLEGSRKFLD  628
               +   KMSKS  NVVNPDDVV +YGADTLR+YEMFMGPLDASIAW+E+GLEGSRKFLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RVWRLIVDEEGKMRDRITTINDGRLTKVYHQTVKKVTEDMANLHFNTAISQLMVFVNEAN  688
            RV RLI   E      IT  N G L KVY++TVK VTE++ ++ FNTAI+QLMVFVN AN
Sbjct  663  RVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  689  KVDALPYEYVEGFVQLLAPIAPHIGEELWQIL-GNEESLTYVPWPTYdeaalvedevevv  747
            K D L  +Y  GFVQL+AP+APH+GEELWQ L ++ ES++YVPWP+YDE+ LVE++VE+V
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  748  FQVNGKLRGKQNVARGLSKEELEQIAMNHEAVKEFIEGKTVRKVIAVPDKLVNIVAN  804
             Q++GK+++K  VA++LS+EEL+++A+ +E V+  I GK + KVIAVP+KLVNIV +
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

139) leuS in NC_017316


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  961 bits (3642),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 593/837 (71%), Positives = 694/837 (83%), Gaps = 42/837 (5%)

Query  19   YNHKEIEKKWQKYWAKNNCFNTLDDPNKEKFYALDMFPYPSGQGLHVGHPEGYTATDILS  78
            Y+H  IE KWQ +WA N+ F+T  D++K KFYALDMFPYPSG GLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  79   RMKRAQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTKKNIETFRRQINSLGFSYDWNR  138
            R KRAQG NVLHPMGWDAFGLPAEQYA+DTGNDPAEFT  NI  F+RQIN+LGFSYDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  139  EINTTDPEYYKWTQWIFTKLYEKGLAYEAEVAVNWVPELGTVISNEEVI-DGKSERGGYD  197
            E+NTTDP+YYKWTQWIFTKLYEKGLAYEAEV+VNWV ELGT I+NEEV+ DG SERGGY 
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  198  VVRRPMRQWMLKITAYADRLLEDLELVDWPESIKDMQRNWIGRSEGANVTFKVAGTEESF  257
            VVR+PMRQWMLKITAYA+RLLEDLE VDWPESIKDMQRNWIG+S GANVTFKV +T+  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  258  TVFTTRPDTLFGATYTVLAPELELVKKITTPEQTAAVEAYIEETSKKSDLNRTDLAKEKT  317
            TVFTTRPDTLFGATY+VLAPE  LV  ITT++Q+ AV  Y  ++S KSDL RTDLAKEKT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  318  GVFTGAYAINPVNGQEIPIWIGDYVLASYGTGAIMAVPAHDERDYEFAKTFGIDILPVIA  377
            GV TG+YAINPVNG+E+P+WI+DYVLASYGTGAIMAVPAHDERD EFAK F +DI+PV+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  378  GGDITTEAYTGDGPHINSDFLNGLNKAEAIAKMNEWLEENHVGKKEVSYRLRDWLFSRQR  437
            GG++   A+T DG HINSDFL+GL+KA AIAKM EWLE + VG+ +V+YRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  438  YWGEPIPVIHWEDGTTTTVPESELPLRLPVTSDIRPSGTGESPLANIDEWVNVVDPETGM  497
            YWGEPIP+IHWEDGT+T+VPESELPL LPVT DIRPSGTGESPLAN+ +W++V   E G+
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT-REDGV  482

Query  498  KGKRETNTMPQWAGSSWYYLRFIDPHNKNEIADFEKLKRWLPVDIYIGGAEHAVLHLLYA  557
            KG+RETNTMPQWAGSSWYYLR+IDPHN + +AD E LK+WLPVDIY+GGAEHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  558  RFWHKFLYDIGVVPTKEPFQKLYNQGMILG------------------------------  587
            RFWHK LYD+GVVPTKEPFQKL+NQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  588  ---ENNEKMSKSRGNVVNPDDVVAKYGADTLRLYEMFMGPLDASIAWNENGLEGSRKFLD  644
               +   KMSKS  NVVNPDDVV +YGADTLR+YEMFMGPLDASIAW+E+GLEGSRKFLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  645  RVWRLIVDEEGKMRDRITTINDGRLTKVYHQTVKKVTEDMANLHFNTAISQLMVFVNEAN  704
            RV RLI   E      IT  N G L KVY++TVK VTE++ ++ FNTAI+QLMVFVN AN
Sbjct  663  RVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  705  KVDALPYEYVEGFVQLLAPIAPHIGEELWQIL-GNEESLTYVPWPTYdeaalvedevevv  763
            K D L  +Y  GFVQL+AP+APH+GEELWQ L ++ ES++YVPWP+YDE+ LVE++VE+V
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  764  FQVNGKLRGKQNVARGLSKEELEQIAMNHEAVKEFIEGKTVRKVIAVPDKLVNIVAN  820
             Q++GK+++K  VA++LS+EEL+++A+ +E V+  I GK + KVIAVP+KLVNIV +
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

140) leuS in NC_009848


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  960 bits (3636),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 567/837 (68%), Positives = 675/837 (81%), Gaps = 42/837 (5%)

Query  48   FQHREIEKKWQDYWLTHKTFATSDSEDKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  107
            ++H  IE KWQ +W  + TF T+    KPKFYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  108  RMKRMQGYDVLHPMGWDAFGLPAEQYALDTGNDPAVFTEENINNFRRQIQSLGFSYDWDR  167
            R KR QG +VLHPMGWDAFGLPAEQYA+DTGNDPA FT ENI NF+RQI++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  168  EINTTDPNYYKWTQWIFLKLYEKGLAYIDEVPVNWCPALGTVLANEEVI-DGKSERGGHP  226
            E+NTTDPNYYKWTQWIF KLYEKGLAY  EVPVNW   LGT +ANEEV+ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  227  VERRPMKQWMLKITAYADRLLEDLEDIDWPESIKDMQRNWIGRSEGAHVHFEIEGHDEQF  286
            V R+PM+QWMLKITAYA+RLLEDLE++DWPESIKDMQRNWIG+S GA+V F + + D +F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  287  TVFTTRPDTLFGATYAVLAPEHALVEKITTATQKEAVEAYIKEIQSKSDLERTDLAKTKT  346
            TVFTTRPDTLFGATYAVLAPEHALV+ ITT+ Q EAV  Y ++   KSDL RTDLAK KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  347  GIFTGAYAVNPLNGEKMPIWIADYVLATYGTGAIMAVPAHDERDYEFAKTFDLPIKAVVE  406
            G+ TG+YA+NP+NG  MP+WIADYVLA+YGTGAIMAVPAHDERD EFAK F+L I +V+E
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  407  GGDIEEEAYTGDGKHINSDFLDGLGKEEAIEKVIAWLEEHQKGEKKVTYRLRDWLFSRQR  466
            GG++EE A+T DG HINSDFLDGL+K  AI K++ WLE +  G+ +VTYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  467  YWGEPIPIIHWEDGTSSAVSEEDLPLILPKTTEIKPSGTGESPLANIKDWVEVVDPVTGK  526
            YWGEPIPIIHWEDGTS+AV+E +LPL+LP T +I+PSGTGESPLAN+ DW+EV     G 
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRE-DGV  482

Query  527  KGRRETNTMPQWAGSCWYFLRYIDPHNSEELASPEKLKKWLPVDVYIGGAEHAVLHLLYA  586
            KGRRETNTMPQWAGS WY+LRYIDPHN+E LA  E LK+WLPVD+Y+GGAEHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  587  RFWHKFLYDIGVVPTKEPFMKLFNQGMILG------------------------------  616
            RFWHK LYD+GVVPTKEPF KLFNQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  617  ---ENNEKMSKSKGNVVNPDDIVESHGADTLRLYEMFMGPLDASIAWSETGLDGARRFLD  673
               +   KMSKS  NVVNPDD+VE  GADTLR+YEMFMGPLDASIAWSE GL+G+R+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  674  RVWRLFTNEDGTISDKVTEQTGGALERSYHETVMKVTDHYEGLRFNTGISQLMVFINDAY  733
            RV RL+T  +      +TE+ +GAL++ Y+ETV  VT++ + ++FNT+I+QLMVF+N A 
Sbjct  663  RVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  734  KADTLPKEYAEGFVKLLSPIAPHLAEELWNKLGHEG-SISYEAWPQYDESKLVDDEVEIV  792
            K D L  +YA GFV+L++P+APHL+EELW+ L   G SISY +WP YDESKLV+++VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  793  VQLNGKVKAKLTVPADATKEQLEDLAKSDARVKEQLEGKTIRKVIAVPGKLVNIVAN  849
            VQ++GKVKAKL V+ D ++E+L+++A ++ +V+ ++ GK I KVIAVP KLVNIV +
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

141) leuS in NC_018065


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  960 bits (3637),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 566/837 (68%), Positives = 685/837 (82%), Gaps = 42/837 (5%)

Query  3    FNHQQIEKKWQTFWDVNKTFKTENEMDKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  62
            ++H  IE KWQ+FW  N TFKT  +  KPKFYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RFKRMQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTAKNIATFKRQINELGFSYDWDR  122
            RFKR QG NVLHPMGWDAFGLPAEQYA+DTGNDPAEFTA NIA FKRQIN LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EINTTDPSYYKWTQWIFTKLVEMDLAYVDEVAVNWCEALGTVLANEEVI-DGVSERGGHP  181
            E+NTTDP+YYKWTQWIFTKL E +LAY  EV+VNW E LGT +ANEEV+ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VVRRPMRQWVLRITKYAdrlvddlvdvdWPESIKEMQRNWIGRSEGAQVKFTVAGTDKNF  241
            VVR+PMRQW+L+IT YA+RL++DL +VDWPESIK+MQRNWIG+S GA+V F V +TDK+F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  EVFTTRPDTLFGATYCVLAPEHKLVADITTAEQKEAVEAYLEKVSLKSDLERTDLAKEKT  301
             VFTTRPDTLFGATY VLAPEH LV  ITT++Q EAV  Y  + SLKSDL RTDLAKEKT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAVNPINGKQVPIWIADYVLATYGTGAIMAVPAHDERDYEFAKEFNLEIIPVLE  361
            GV TG+YA+NP+NGK++P+WIADYVLA+YGTGAIMAVPAHDERD EFAK+FNL+IIPVLE
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGDIENEAFTGDGAHINSDFLNGLNKADGIAKAIEWLVENGVGEKKITYRLRDWLFSRQR  421
            GG++E+ AFT DG HINSDFL+GL+KA +IAK +EWL  +GVG+ ++TYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPVIHWEDGTMTTIPVEELPLELPKTTNIRPSGTGESPLANIEEWVNVVDPVTGK  481
            YWGEPIP+IHWEDGT T++P  ELPL LP T +IRPSGTGESPLAN+ +W++V     G 
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT-REDGV  482

Query  482  KGRRETNTMPQWAGSSWYFLRYIDPKNDQALADPELLKHWLPVDIYIGGAEHAVLHLLYA  541
            KGRRETNTMPQWAGSSWY+LRYIDP N + LAD ELLK+WLPVDIY+GGAEHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKVLYDLGLVHTKEPFQKLFNQGMILG------------------------------  571
            RFWHKVLYDLG+V TKEPFQKLFNQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---EGNEKMSKSKGNVVNPDDIIVSHGADTLRLYEMFMGPLEASVAWSTNGLDGARRFLD  628
               ++  KMSKS  NVVNPDD++   GADTLR+YEMFMGPL+AS+AWS +GL+G+R+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RIWRLFVTDEGKLAAKVQDSADTTLEKVYHQTVKKVTEDYEGIRFNTAISQMMVFINDCY  688
            R+ RL+ T E      + +    +L+KVY++TVK VTE+ + ++FNTAI+Q+MVF+N   
Sbjct  663  RVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  689  KAEVIPTEYAKGFVKLLSPIAPHIAEELWSIL-GHEDTITYATWPTFDESKLVDDEIEVV  747
            K + + ++YAKGFV+L++P+APH++EELW  L +  ++I+Y  WP++DESKLV++++E+V
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  748  VQVLGKVRAKVTVAKDITKEDLEKVALADSKVQEFIEGKTVVKVIVIPGKLVNIVVK  804
            VQ+ GKV+AK+ VAKD+++E+L+ VALA+ KVQ  I GK ++KVI +P KLVNIV+K
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

142) MPTP_1662 in NC_015516


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  958 bits (3631),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 571/837 (69%), Positives = 675/837 (81%), Gaps = 42/837 (5%)

Query  3    YDHKKIEKKWQNYWAMNNTFITKEEPDREKFYALDMFPYPSGKGLHVGHPEGYTATDILS  62
            YDH  IE KWQ +WA N+TF T  ++ + KFYALDMFPYPSG GLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMKRSQGYNVLHPMGWDAFGLPAEQYALDTENDPEVFTKENIETFKRQINSLGFSYDWNR  122
            R KR+QG NVLHPMGWDAFGLPAEQYA+DT NDP  FT ENI  FKRQIN+LGFSYDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EISTTNPDYYKWTQWIFTKLYEKGLAYEAEVAVNWVPELGTVISNEEVI-DGKSERGGYD  181
            E++TT+P+YYKWTQWIFTKLYEKGLAYEAEV+VNWV ELGT I+NEEV+ DG SERGGY 
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VIRKPMRQWMLKITAYADRLLKDLDLVDWPENIKDMQRNWIGRSEGANITFQVAGIEQAF  241
            V+RKPMRQWMLKITAYA+RLL DL+ VDWPE+IKDMQRNWIG+S GAN+TF+V + ++ F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  TVFTTRADTLFGATYTVLAPEHKLVKEITIPKQQKMVEKYVAEAAKKSDLMRTELAKEKT  301
            TVFTTR+DTLFGATY+VLAPEH LV  IT + Q   V  Y  +A+ KSDL RT+LAKEKT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAINPVNNKKIPIWISDYVLSSYGTGAIMAVPAHDERDYAFAKTFNLEILPVID  361
            GV TG+YAINPVN K +P+WI+DYVL+SYGTGAIMAVPAHDERD  FAK FNL+I+PV++
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGNVEEEAYTGNGRHINSGFLDGLDKETAISTMIGWLEEHKVGEKKVSYRLRDWLFSRQR  421
            GGNVEE A+T +G HINS+FLDGLDK +AI+ M+ WLE + VG+ +V+YRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPIIHWEDGTTSVVPESELPLCLPKVTDIHPSGTGESPLANIEDWINVIDPKTGK  481
            YWGEPIPIIHWEDGT++ VPESELPL LP   DI+PSGTGESPLAN+ DW++V     G 
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT-REDGV  482

Query  482  KGKRETNTMPQWAGSSWYYLRFIDPYNKEKIASYEALERWLPVDIYIGGAEHAVLHLLYA  541
            KG+RETNTMPQWAGSSWYYLR+IDP N EK+A  E L +WLPVDIY+GGAEHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKFLYDLGVVPTKEPFQKLYNQGMILG------------------------------  571
            RFWHK LYDLGVVPTKEPFQKL+NQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---KNNEKMSKSRGNVVNPDDVIEKYGADTLRLYEMFMGPLDASIAWSENGLEGSRKFLD  628
               +   KMSKS  NVVNPDDV+E+YGADTLR+YEMFMGPLDASIAWSE+GLEGSRKFLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RVWRLLVSETGTMNARIIKTNDGQLTKLYNQTVKKVTEDLEAMHFNTAISQLMIFVNEAN  688
            RV RL+ +        I   N G L K+YN+TVK VTE+++ M FNTAI+QLM+FVN AN
Sbjct  663  RVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  689  KIAELPYNYALGFVQLLAPIVPHLGEELWEIL-GKTDSISYAPWPEYDESVLVEEETEII  747
            K   L  +YA GFVQL+AP+ PHLGEELW+ L +  +SISY PWP YDES LVE++ EI+
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  748  FQVNGKVRGKMTLPKGLGKEELEQKALTIESIQRILEGKNIHKVIVIPDKLVNIVAK  804
             Q++GKV++K+ ++K+L++EEL++ AL+ E +Q  + GK+I KVI +P+KLVNIV K
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

143) leuS in NC_009328


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  950 bits (3600),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 563/838 (68%), Positives = 676/838 (81%), Gaps = 43/838 (5%)

Query  9    FNHREIEKKWQDYWEQHKTFRTPDESDKPKFYVLDMFPYPSGAGLHVGHPEGYTATDILA  68
            ++H  IE KWQ +W ++ TF+T  ++ KPKFY LDMFPYPSGAGLHVGHPEGYTATDIL+
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  69   RMKRMQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTQKNIDNFRRQIKSLGFSYDWDR  128
            R KR QG NVLHPMGWDAFGLPAEQYA+DTGNDPAEFT  NI NF+RQI++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  129  EINTTDPNYYKWTQWIFLKLYEKGLAYMDEVPVNWCPALGTVLANEEVI-NGRSERGGHP  187
            E+NTTDPNYYKWTQWIF KLYEKGLAY  EVPVNW   LGT +ANEEV+ +G SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  188  VIRKPMRQWMLKITAYAdrlledleeldWPESIKEMQRNWIGRSEGAEIEFAVDGHDESF  247
            V+RKPMRQWMLKITAYA+RLLEDLEE+DWPESIK+MQRNWIG+S GA++ F V + D  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  248  TVFTTRPDTLFGATYAVLAPEHPLVEKITTPEQKPAVDAYLKEVQSKSDLERTDLAKEKT  307
            TVFTTRPDTLFGATYAVLAPEH+LV+ ITT++Q  AV  Y ++   KSDL RTDLAKEKT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  308  GVFTGAYAIHPVTGDKLPIWIADYVLMGYGTGAIMAVPAHDERDYEFAKTFNLPIKEVVA  367
            GV TG+YAI+PV G  +P+WIADYVL +YGTGAIMAVPAHDERD EFAK FNL I  V+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  368  GGNVENEPYTGDGEHINSEFLNGLNKQEAIEKMIAWLEENGKGQKKVSYRLRDWLFSRQR  427
            GGNVE+ ++T DG HINS+FL+GL+K  AI KM+ WLE +G G+ +V+YRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  428  YWGEPIPVIHWEDGTMTTVPEEELPLVLPKTDEIKPSGTGESPLANIEEWVNVVDPKTGK  487
            YWGEPIP+IHWEDGT T+VPE ELPLVLP T +I+PSGTGESPLAN+ +W++V     G 
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT-REDGV  482

Query  488  KGRRETNTMPQWAGSCWYYLRYIDPHNDKQLADPEKLKQWLPVDVYIGGAEHAVLHLLYA  547
            KGRRETNTMPQWAGS WYYLRYIDPHN  +LAD E LKQWLPVD+Y+GGAEHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  548  RFWHKVLYDLGIVPTKEPFQKLFNQGMILG------------------------------  577
            RFWHKVLYDLG+VPTKEPFQKLFNQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  578  ---ENNEKMSKSKGNVVNPDDIVESHGADTLRLYEMFMGPLEASIAWSTKGLDGARRFLE  634
               +   KMSKS  NVVNPDD+VE  GADTLR+YEMFMGPL+ASIAWS  GL+G+R+FL+
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  635  RVWRLFVTEDGQLNPNIVDEPANDTLERVYHQTVKKVTEDYEALRFNTAISQLMVFINEA  694
            RV RL+ T +       + E  +++L++VY++TVK VTE+ + ++FNTAI+QLMVF+N A
Sbjct  663  RVYRLITTKE-------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAA  715

Query  695  YKAEQMKKEYMEGFVKLLSPVCPHIGEELWQKL-GHTDTIAYEPWPTYDEAKLVEDVVEI  753
             K +++  +Y  GFV+L++P  PH+GEELWQ L +  ++I+Y PWP+YDE+KLVE+ VEI
Sbjct  716  NKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEI  775

Query  754  VIQINGKVRAKLNVPADLSKEALEERALADEKIKEQLAGKTVRKVITVPGKLVNIVAN  811
            V+QI+GKV+AKL V+ DLS+E L+E ALA+EK++ ++AGK + KVI+VP KLVNIV +
Sbjct  776  VVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

144) leuS in NC_019425


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  949 bits (3597),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 573/837 (69%), Positives = 690/837 (83%), Gaps = 42/837 (5%)

Query  3    YNHKTIEKKWQKYWAAHNSFNTTEDPKKENFYALDMFPYPSGQGLHVGHPEGYTATDILA  62
            Y+H +IE KWQ +WA +++F+T  D+ K +FYALDMFPYPSG GLHVGHPEGYTATDIL+
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMKRSQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTEHNIGTFRRQINSLGFSYDWNR  122
            R KR+QG NVLHPMGWDAFGLPAEQYA+DTGNDPAEFT +NI+ F+RQIN+LGFSYDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EINTTDPHYYKWTQWIFTKLYEKGLAYEAEVAVNWCPALGTVLANEEVI-DGKSERGGFP  181
            E+NTTDP+YYKWTQWIFTKLYEKGLAYEAEV+VNW   LGT +ANEEV+ DG SERGG+P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VYRKPMKQWMLKITAYAERLLDDLETVDWPESIKDMQRNWIGKSVGANVTFKIKDRSEDF  241
            V RKPM+QWMLKITAYAERLL+DLE VDWPESIKDMQRNWIGKS GANVTFK+KD   DF
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  TVFTTRPDTLFGATYAVLAPELDLVKEITTPEQKEAVEAYITEVSLKTDLDRTDLAKSKT  301
            TVFTTRPDTLFGATYAVLAPE  LV  ITT++Q EAV  Y  + SLK+DL RTDLAK KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAVNPVNGQEIPIWIADYVLATYGTGAIMAVPAHDERDYEFAKTFNLTIIPVLE  361
            GV TG+YA+NPVNG+E+P+WIADYVLA+YGTGAIMAVPAHDERD EFAK FNL IIPVLE
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGNVAEEPYTGDGVHVNSGFLDGLDKETAIEVMNKWLEENGHGKKEITYRLRDWLFSRQR  421
            GGNV E ++T DG+H+NS+FLDGLDK +AI  M  WLE +G G+ ++TYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPVIHWEDGTTTAlpeselplllpKTDEIKPSGTGESPLANISEWVNVVDPETGM  481
            YWGEPIP+IHWEDGT+TA+PESELPL+LP T +I+PSGTGESPLAN+++W++V   E G+
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT-REDGV  482

Query  482  KGRRETNTMPQWAGSSWYFLRFIDPHNKNEIASKEKLEKWLPVDIYIGGAEHAVLHLLYA  541
            KGRRETNTMPQWAGSSWY+LR+IDPHN + +A  E L +WLPVDIY+GGAEHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKFLYDIGVVPTKEPFQKLYNQGMILG------------------------------  571
            RFWHK LYD+GVVPTKEPFQKL+NQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---ENNEKMSKSKGNVVNPDDVVEKFGADTLRMYEMFMGPLDSAIAWSENGLEGSRKFLD  628
               +   KMSKS  NVVNPDDVVE++GADTLR+YEMFMGPLD++IAWSE+GLEGSRKFLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RVWRLVVDEEGKLRDRITTINNGKLDRVYHQTVKKVTEDYQSLHFNTAISQMMVFVNEAY  688
            RV RL+   E      IT  N+G LD+VY++TVK VTE+ + + FNTAI+Q+MVFVN A 
Sbjct  663  RVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  689  KTDALPIEYVAGLVQLLAPIAPHVSEELWEKL-GNESSLTYVSWPTYDESFLVESEVEVI  747
            K D L  +Y  G+VQL+AP+APH++EELW+ L ++  S++YV+WP+YDES LVE++VE++
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  748  FQVNGKVKAKAMVPKDIAKDDMETLATENEAIKEALVGKTVRKVIVVPGKLVNIVAN  804
             Q++GKVKAK +V+KD+++++++ +A  NE ++  + GK + KVI VP KLVNIV +
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

145) leuS in NC_010184


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  949 bits (3597),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 555/837 (67%), Positives = 666/837 (80%), Gaps = 44/837 (5%)

Query  3    FNHQEIEKKWQGHWEENKTFRTPDETEKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  62
            ++H  IE KWQ+ W +N TF+T  ++ KPKFYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMKRMQGYNVLHPMGWDAFGLPAEQYALDTGNSPAEFTELNINTFRNQIKALGFSYDWDR  122
            R KR QG NVLHPMGWDAFGLPAEQYA+DTGN PAEFT  NI  F+ QI+ALGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVNTTDPTYYKWTQWIFLKLFEKGLAYVDEVPVNWCPALGTVLANEEII-DGKSERGGHP  181
            EVNTTDP YYKWTQWIF KL+EKGLAY  EVPVNW   LGT +ANEE++ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRPMRQWMLKITAYGDRLLEDLDELNWPESLKDMQRNWIGRSEGAEVHFNIDGTDEKF  241
            V R+PMRQWMLKITAY++RLLEDL+E++WPES+KDMQRNWIG+S GA+V F++ +TD  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  TVFTTRPDTLFGASYCVLAPEHALVANITIPEQKEAVEAYINSVKMKSDLERTELAKEKT  301
            TVFTTRPDTLFGA+Y VLAPEHALV  IT ++Q EAV  Y     +KSDL RT+LAKEKT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAVNPVNGEKLPIWIADYVLATYGTGAVMAVPAHDERDYEFASTFNLPMKEVVK  361
            GV TG+YA+NPVNG  +P+WIADYVLA+YGTGA+MAVPAHDERD EFA  FNL +  V+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGDISKEAYTGDGAHVNSAFLDGLNKEKAIVKMIEWLEVTSAGNQKVTYRLRDWLFSRQR  421
            GG++   A+T DG H+NS FLDGL+K  AI KM+EWLE  + GN++VTYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPVIHWEDGTMTAVKEEELPLVLPKTENIRPSGTGESPLANIEEWVNVVDPETGK  481
            YWGEPIP+IHWEDGT TAV E ELPLVLP T +IRPSGTGESPLAN+ +W++V   E G 
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT-REDGV  482

Query  482  KGRRETNTMPQWAGSCWYYLRYIDPNNSEALVDPEKVKQWLPVDIYIGGAEHAVLHLLYA  541
            KGRRETNTMPQWAGS WYYLRYIDP+N+E L D E +KQWLPVDIY+GGAEHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKVLYDIGVVPTKEPFQQLFNQGMILG------------------------------  571
            RFWHKVLYD+GVVPTKEPFQ+LFNQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---ENNEKMSKSKGNVVNPDDIVASHGADTLRLYEMFMGPLDASIAWSENGLDGARRFLD  628
               +   KMSKS  NVVNPDD+V   GADTLR+YEMFMGPLDASIAWSE+GL+G+R+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RVWRLFIQENGELSEKITDAPNKDLEKAYHQTVKKVTEDYAELRFNTAISQMMVFINDAY  688
            RV RL+       +  IT+  +  L+K Y++TVK VTE+  +++FNTAI+Q+MVF+N A 
Sbjct  663  RVYRLIT------TKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  689  KAETLPKEYVEGFVKMIAPVAPHIGEELWNKL-GYSETITYASWPTFDESKLVEDEVEIV  747
            K + L  +Y  GFV++IAP APH+GEELW+ L + +E+I+Y +WP++DESKLVE++VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  748  VQIMGKVRTKLTMSKDASKEEMEQLAL--EAIKEQIEGKTVRKVIVVPGKLVNVVAN  802
            VQI GKV++KL ++KD S+EE++++AL  E ++ +I GK + KVI VP KLVN+V +
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

146) leuS in NC_013891


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  948 bits (3591),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 568/836 (68%), Positives = 694/836 (84%), Gaps = 41/836 (4%)

Query  6    FNHKKVEPKWQQYWSEHNTFKTTEDKNKENFYALDMFPYPSGAGLHVGHPEGYTATDILS  65
            ++H  +EPKWQ +W++++TFKT  D +K +FYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  66   RMKRMQGKNVLHPIGWDAFGLPAEQYAIDTGNDPEEFTALNIANFTRQIKSLGFSYDWER  125
            R KR QG NVLHP+GWDAFGLPAEQYA+DTGNDP EFTA NIANF RQI++LGFSYDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  126  EINTTDPEYYKWTQWIFEKLYENGLAYEAEIAVNWCPALGTVLANEEVI-DGKSERGGFP  184
            E+NTTDP+YYKWTQWIF KLYE+GLAYEAE++VNW   LGT +ANEEV+ DG SERGG+P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  185  VFRKPMRQWMLKITAYAdrllddldlvdWPENIKDMQRNWIGRSEGAEVTFKIKDSDETF  244
            V RKPMRQWMLKITAYA+RLL+DL+ VDWPE+IKDMQRNWIG+S GA+VTFK+KD+D  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  245  NVFTTRPDTLFGATYTVFAPEHELVEKITTAAQKDAVEAYKKQVELKSELERTDLAKDKT  304
             VFTTRPDTLFGATY+V+APEH LV+ ITT+ Q +AV  YK+Q  LKS+L RTDLAK+KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  305  GVFTGAYAINPINGEEVPVWIADYVLIQYGTGAIMAVPAHDERDYEFAKQFGLNIRPVLE  364
            GV TG+YAINP+NG E+PVWIADYVL  YGTGAIMAVPAHDERD EFAKQF L+I PVLE
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  365  GGDVTKEAFTGDGPHINSDFLNGLDKTEAITAAIDWLEKEQIGSRKITYRLRDWLFSRQR  424
            GG+V   AFT DG HINSDFL+GLDK+ AI+  ++WLE E +G+ ++TYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  425  YWGEPIPVIHWEDGettlvpeeelplllpkateIKPSGTGESPLANLHDWVNVTDENGRK  484
            YWGEPIP+IHWEDG +T VPE ELPL+LP + +I+PSGTGESPLAN+ DW++VT E+G K
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  485  GRRETNTMPQWAGSSWYFLRYIDPNNTEAIADKEKLAEWLPVDVYIGGAEHAVLHLLYAR  544
            GRRETNTMPQWAGSSWY+LRYIDP+NTE +AD E L +WLPVD+Y+GGAEHAVLHLLYAR
Sbjct  484  GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYAR  543

Query  545  FWHKFLYDIGVVPTKEPFQKLFNQGMILG-------------------------------  573
            FWHK LYD+GVVPTKEPFQKLFNQGMILG                               
Sbjct  544  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEE  603

Query  574  --ENNEKMSKSRGNVVNPDEVVEKYGADTLRMYEMFMGPLEASIAWNENGLEGSRKFLDR  631
              +   KMSKS  NVVNPD+VVE+YGADTLR+YEMFMGPL+ASIAW+E+GLEGSRKFLDR
Sbjct  604  LEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR  663

Query  632  IWRLLVTEEGTLAEKVTTEPNANLEKAYHHMVKTVTNHFENLRFNTGISQLMIFINEAYK  691
            + RL+ T E      +T E ++ L+K Y++ VK+VT++ ++++FNT+I+QLM+F+N A K
Sbjct  664  VYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANK  717

Query  692  QDTIPKEYVEGFVQLLSPIAPHLAEELWEIL-GHTETISYVSWPTYDETKLVEDEVEIVL  750
            +D +  +Y  GFVQL++P+APHL+EELW+ L +  E+ISYV+WP+YDE+KLVE++VEIV+
Sbjct  718  EDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVV  777

Query  751  QVNGKVKSKITVAKSLAKDELEKVAQNDEKIKENLEGKTIRKVIVVPGKLVNIVAN  806
            Q++GKVK+K+ VAK L+++EL+ VA  +EK++ ++ GK I KVI VP KLVNIV +
Sbjct  778  QIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

147) leuS in NC_018586


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  946 bits (3586),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 564/836 (68%), Positives = 694/836 (84%), Gaps = 41/836 (4%)

Query  6    FNHKKMEPKWQQYWSEHNTFKTTEDKNKDNFYALDMFPYPSGAGLHVGHPEGYTATDILS  65
            ++H  +EPKWQ +W++++TFKT  D +K +FYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  66   RMKRMQGKNVLHPIGWDAFGLPAEQYAIDTGNDPEEFTALNIANFTRQIKSLGFSYDWDR  125
            R KR QG NVLHP+GWDAFGLPAEQYA+DTGNDP EFTA NIANF RQI++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  126  EINTTDPEYYKWTQWIFEKLYEKGLAYEAEIAVNWCPALGTVLANEEVI-DGKSERGGFP  184
            E+NTTDP+YYKWTQWIF KLYEKGLAYEAE++VNW   LGT +ANEEV+ DG SERGG+P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  185  VFRKPMRQWMLKITAYAdrllddldlvdWPENIKDMQRNWIGRSEGAEVTFKIKDSDETF  244
            V RKPMRQWMLKITAYA+RLL+DL+ VDWPE+IKDMQRNWIG+S GA+VTFK+KD+D  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  245  NVFTTRPDTLFGATYTVFAPEHELIEKITTPEQKEAVEAYKKQVELKSELERTDLAKDKT  304
             VFTTRPDTLFGATY+V+APEH L++ ITT++Q EAV  YK+Q  LKS+L RTDLAK+KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  305  GVFTGAYAINPINGEEVPIWIADYVLIQYGTGAIMAVPAHDERDFEFAQQFGLNIRPVLE  364
            GV TG+YAINP+NG E+P+WIADYVL  YGTGAIMAVPAHDERD EFA+QF L+I PVLE
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  365  GGDVTKEAFTDDGPHINSDFLNGLAKAEAITAAIDWLEKEGIGSRKITYRLRDWLFSRQR  424
            GG+V   AFT+DG HINSDFL+GL KA AI+  ++WLE EG+G+ ++TYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  425  YWGEPIPVIHWEDGettlvpedelplllpKATEIKPSGTGESPLANLHDWVNVTDKNGRK  484
            YWGEPIP+IHWEDG +T VPE ELPL+LP + +I+PSGTGESPLAN+ DW++VT  +G K
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  485  GRRETNTMPQWAGSSWYFLRYIDPNNSEAIADKEKLAEWLPVDVYIGGAEHAVLHLLYAR  544
            GRRETNTMPQWAGSSWY+LRYIDP+N+E +AD E L +WLPVD+Y+GGAEHAVLHLLYAR
Sbjct  484  GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYAR  543

Query  545  FWHKFLYDIGVVPTKEPFQKLFNQGMILG-------------------------------  573
            FWHK LYD+GVVPTKEPFQKLFNQGMILG                               
Sbjct  544  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEE  603

Query  574  --ENNEKMSKSRGNVVNPDEVVEKYGADTLRLYEMFMGPLEASIAWNENGLEGARKFLDR  631
              +   KMSKS  NVVNPD+VVE+YGADTLR+YEMFMGPL+ASIAW+E+GLEG+RKFLDR
Sbjct  604  LEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR  663

Query  632  IWRLLVTEEGTLAEKVTTDANANLEKAYHHMVKTVTNHYENLRFNTGISQLMIFINEAYK  691
            + RL+ T E      +T + ++ L+K Y++ VK+VT++ ++++FNT+I+QLM+F+N A K
Sbjct  664  VYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANK  717

Query  692  QDTIPKQYVEGFVQLLSPIAPHLAEELWEIL-GHTETISYVAWPTYDETKLVEDEVEIVL  750
            +D +  +Y  GFVQL++P+APHL+EELW+ L +  E+ISYV+WP+YDE+KLVE++VEIV+
Sbjct  718  EDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVV  777

Query  751  QVNGKVKSKITVAKSLEKEELEKIAQEDNKMKENLEGKTIRKVIVVPGKLVNIVAN  806
            Q++GKVK+K+ VAK L +EEL+ +A  ++K++ ++ GK I KVI VP KLVNIV +
Sbjct  778  QIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

148) leuS in NC_017728


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  945 bits (3579),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 564/836 (68%), Positives = 693/836 (83%), Gaps = 41/836 (4%)

Query  3    FNHKKMEPKWQQYWSEHNTFKTTEDKNKDNFYALDMFPYPSGAGLHVGHPEGYTATDILS  62
            ++H  +EPKWQ +W++++TFKT  D +K +FYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMKRMQGKNVLHPIGWDAFGLPAEQYAIDTGNDPEEFTALNIANFTRQIKSLGFSYDWDR  122
            R KR QG NVLHP+GWDAFGLPAEQYA+DTGNDP EFTA NIANF RQI++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EINTTDPEYYKWTQWIFEKLYEKGLAYEAEIAVNWCPALGTVLANEEVI-DGKSERGGFP  181
            E+NTTDP+YYKWTQWIF KLYEKGLAYEAE++VNW   LGT +ANEEV+ DG SERGG+P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VFRKPMRQWMLKITAYAdrllddldlvdWPENIKDMQRNWIGRSEGAEVTFKIKDSDETF  241
            V RKPMRQWMLKITAYA+RLL+DL+ VDWPE+IKDMQRNWIG+S GA+VTFK+KD+D  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  NVFTTRPDTLFGATYTVFAPEHELIEKITTPEQKEAVEAYKKQVELKSELERTDLAKDKT  301
             VFTTRPDTLFGATY+V+APEH L++ ITT++Q EAV  YK+Q  LKS+L RTDLAK+KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAINPINGEEVPIWIADYVLIQYGTGAIMAVPAHDERDFEFAQQFGLNIRPVLE  361
            GV TG+YAINP+NG E+P+WIADYVL  YGTGAIMAVPAHDERD EFA+QF L+I PVLE
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGDVTKEAFTGDGPHINSDFLNGLAKAEAITAAIDWLEKEGIGSRKITYRLRDWLFSRQR  421
            GG+V   AFT DG HINSDFL+GL KA AI+  ++WLE EG+G+ ++TYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPVIHWEDGettlvpedelplllpKATEIKPSGTGESPLANLHDWVNVTDKNGRK  481
            YWGEPIP+IHWEDG +T VPE ELPL+LP + +I+PSGTGESPLAN+ DW++VT  +G K
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  482  GRRETNTMPQWAGSSWYFLRYIDPNNSEAIADKEKLAEWLPVDVYIGGAEHAVLHLLYAR  541
            GRRETNTMPQWAGSSWY+LRYIDP+N+E +AD E L +WLPVD+Y+GGAEHAVLHLLYAR
Sbjct  484  GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYAR  543

Query  542  FWHKFLYDIGVVPTKEPFQKLFNQGMILG-------------------------------  570
            FWHK LYD+GVVPTKEPFQKLFNQGMILG                               
Sbjct  544  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEE  603

Query  571  --ENNEKMSKSRGNVVNPDEVVEKYGADTLRLYEMFMGPLEASIAWNENGLEGARKFLDR  628
              +   KMSKS  NVVNPD+VVE+YGADTLR+YEMFMGPL+ASIAW+E+GLEG+RKFLDR
Sbjct  604  LEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR  663

Query  629  IWRLLVTEEGTLAEKVTTDANANLEKAYHHMVKTVTNHYENLRFNTGISQLMIFINEAYK  688
            + RL+ T E      +T + ++ L+K Y++ VK+VT++ ++++FNT+I+QLM+F+N A K
Sbjct  664  VYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANK  717

Query  689  QDTIPKQYVEGFVQLLSPIAPHLAEELWEIL-GHTETISYVAWPTYDETKLVEDEVEIVL  747
            +D +  +Y  GFVQL++P+APHL+EELW+ L +  E+ISYV+WP+YDE+KLVE++VEIV+
Sbjct  718  EDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVV  777

Query  748  QVNGKVKSKITVAKSLEKEELEKIAQEDNKMKENLEGKTIRKVIVVPGKLVNIVAN  803
            Q++GKVK+K+ VAK L +EEL+ +A  ++K++ ++ GK I KVI VP KLVNIV +
Sbjct  778  QIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

149) LMRG_01307 in NC_017544


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  945 bits (3579),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 565/836 (68%), Positives = 694/836 (84%), Gaps = 41/836 (4%)

Query  6    FNHKKMEPKWQQYWSEHNTFKTTEDKNKENFYALDMFPYPSGAGLHVGHPEGYTATDILS  65
            ++H  +EPKWQ +W++++TFKT  D +K +FYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  66   RMKRMQGKNVLHPIGWDAFGLPAEQYAIDTGNDPEEFTALNIANFTRQIKSLGFSYDWDR  125
            R KR QG NVLHP+GWDAFGLPAEQYA+DTGNDP EFTA NIANF RQI++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  126  EINTTDPEYYKWTQWIFEKLYEKGLAYEAEIAVNWCPALGTVLANEEVI-DGKSERGGFP  184
            E+NTTDP+YYKWTQWIF KLYEKGLAYEAE++VNW   LGT +ANEEV+ DG SERGG+P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  185  VFRKPMRQWMLKITAYAdrllddldlvdWPENIKDMQRNWIGRSEGAEVTFKIKDSDETF  244
            V RKPMRQWMLKITAYA+RLL+DL+ VDWPE+IKDMQRNWIG+S GA+VTFK+KD+D  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  245  NVFTTRPDTLFGATYTVFAPEHELIEKITTPEQKEAVEAYKKQVELKSELERTDLAKDKT  304
             VFTTRPDTLFGATY+V+APEH L++ ITT++Q EAV  YK+Q  LKS+L RTDLAK+KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  305  GVFTGAYAINPINGEEVPIWIADYVLIQYGTGAIMAVPAHDERDFEFAQQFGLNIRPVLE  364
            GV TG+YAINP+NG E+P+WIADYVL  YGTGAIMAVPAHDERD EFA+QF L+I PVLE
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  365  GGDVTKEAFTGDGPHINSDFLNGLAKAEAITAAIDWLEKEGIGSRKITYRLRDWLFSRQR  424
            GG+V   AFT DG HINSDFL+GL KA AI+  ++WLE EG+G+ ++TYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  425  YWGEPIPVIHWEDGettlvpeeelplllpkateIKPSGTGESPLANLHDWVNVTDENGRK  484
            YWGEPIP+IHWEDG +T VPE ELPL+LP + +I+PSGTGESPLAN+ DW++VT E+G K
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  485  GRRETNTMPQWAGSSWYFLRYIDPKNSEAIADKEKLAEWLPVDVYIGGAEHAVLHLLYAR  544
            GRRETNTMPQWAGSSWY+LRYIDP N+E +AD E L +WLPVD+Y+GGAEHAVLHLLYAR
Sbjct  484  GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYAR  543

Query  545  FWHKFLYDIGVVPTKEPFQKLFNQGMILG-------------------------------  573
            FWHK LYD+GVVPTKEPFQKLFNQGMILG                               
Sbjct  544  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEE  603

Query  574  --ENNEKMSKSRGNVVNPDEVVEKYGADTLRLYEMFMGPLEASIAWNENGLEGARKFLDR  631
              +   KMSKS  NVVNPD+VVE+YGADTLR+YEMFMGPL+ASIAW+E+GLEG+RKFLDR
Sbjct  604  LEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR  663

Query  632  IWRLLVTEEGTLAEKVTTDANANLEKAYHHMVKTVTNHYENLRFNTGISQLMIFINEAYK  691
            + RL+ T E      +T + ++ L+K Y++ VK+VT++ ++++FNT+I+QLM+F+N A K
Sbjct  664  VYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANK  717

Query  692  QDTIPKQYVEGFVQLLSPIAPHLAEELWEIL-GHTETISYVAWPTYDEAKLVEDEVEIVL  750
            +D +  +Y  GFVQL++P+APHL+EELW+ L +  E+ISYV+WP+YDE+KLVE++VEIV+
Sbjct  718  EDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVV  777

Query  751  QVNGKVKSKITVAKSLGKEELEKIAQEDNKMKENLEGKTIRKVIVVPGKLVNIVAN  806
            Q++GKVK+K+ VAK L++EEL+ +A  ++K++ ++ GK I KVI VP KLVNIV +
Sbjct  778  QIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

150) leuS in NC_018584


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  945 bits (3581),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 564/836 (68%), Positives = 693/836 (83%), Gaps = 41/836 (4%)

Query  6    FNHKKMEPKWQQYWSEHNTFKTTEDKNKDNFYALDMFPYPSGAGLHVGHPEGYTATDILS  65
            ++H  +EPKWQ +W++++TFKT  D +K +FYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  66   RMKRMQGKNVLHPIGWDAFGLPAEQYAIDTGNDPEEFTALNIANFTRQIKSLGFSYDWDR  125
            R KR QG NVLHP+GWDAFGLPAEQYA+DTGNDP EFTA NIANF RQI++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  126  EINTTDPEYYKWTQWIFEKLYEKGLAYEAEIAVNWCPALGTVLANEEVI-DGKSERGGFP  184
            E+NTTDP+YYKWTQWIF KLYEKGLAYEAE++VNW   LGT +ANEEV+ DG SERGG+P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  185  VFRKPMRQWMLKITAYAdrllddldlvdWPENIKDMQRNWIGRSEGAEVTFKIKDSDETF  244
            V RKPMRQWMLKITAYA+RLL+DL+ VDWPE+IKDMQRNWIG+S GA+VTFK+KD+D  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  245  NVFTTRPDTLFGATYTVFAPEHELIEKITTPEQKEAVEAYKKQVELKSELERTDLAKDKT  304
             VFTTRPDTLFGATY+V+APEH L++ ITT++Q EAV  YK+Q  LKS+L RTDLAK+KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  305  GVFTGAYAINPINGEEVPIWIADYVLIQYGTGAIMAVPAHDERDFEFAQQFGLNIRPVLE  364
            GV TG+YAINP+NG E+P+WIADYVL  YGTGAIMAVPAHDERD EFA+QF L+I PVLE
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  365  GGDVTKEAFTGDGPHINSDFLNGLAKAEAITAAIDWLEKEGIGSRKITYRLRDWLFSRQR  424
            GG+V   AFT DG HINSDFL+GL KA AI+  ++WLE EG+G+ ++TYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  425  YWGEPIPVIHWEDGettlvpedelplllpKATEIKPSGTGESPLANLHDWVNVTDKNGRK  484
            YWGEPIP+IHWEDG +T VPE ELPL+LP + +I+PSGTGESPLAN+ DW++VT  +G K
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  485  GRRETNTMPQWAGSSWYFLRYIDPNNSEAIADKEKLAEWLPVDVYIGGAEHAVLHLLYAR  544
            GRRETNTMPQWAGSSWY+LRYIDP+N+E +AD E L +WLPVD+Y+GGAEHAVLHLLYAR
Sbjct  484  GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYAR  543

Query  545  FWHKFLYDIGVVPTKEPFQKLFNQGMILG-------------------------------  573
            FWHK LYD+GVVPTKEPFQKLFNQGMILG                               
Sbjct  544  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEE  603

Query  574  --ENNEKMSKSRGNVVNPDEVVEKYGADTLRLYEMFMGPLEASIAWNENGLEGARKFLDR  631
              +   KMSKS  NVVNPD+VVE+YGADTLR+YEMFMGPL+ASIAW+E+GLEG+RKFLDR
Sbjct  604  LEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR  663

Query  632  IWRLLVTEEGTLAEKVTTDANANLEKAYHHMVKTVTNHYENLRFNTGISQLMIFINEAYK  691
            + RL+ T E      +T + ++ L+K Y++ VK+VT++ ++++FNT+I+QLM+F+N A K
Sbjct  664  VYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANK  717

Query  692  QDTIPKQYVEGFVQLLSPIAPHLAEELWEIL-GHTETISYVAWPTYDETKLVEDEVEIVL  750
            +D +  +Y  GFVQL++P+APHL+EELW+ L +  E+ISYV+WP+YDE+KLVE++VEIV+
Sbjct  718  EDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVV  777

Query  751  QVNGKVKSKITVAKSLEKEELEKIAQEDNKMKENLEGKTIRKVIVVPGKLVNIVAN  806
            Q++GKVK+K+ VAK L +EEL+ +A  ++K++ ++ GK I KVI VP KLVNIV +
Sbjct  778  QIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

151) leuS in NC_012488


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  945 bits (3579),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 564/836 (68%), Positives = 693/836 (83%), Gaps = 41/836 (4%)

Query  3    FNHKKMEPKWQQYWSEHNTFKTTEDKNKDNFYALDMFPYPSGAGLHVGHPEGYTATDILS  62
            ++H  +EPKWQ +W++++TFKT  D +K +FYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMKRMQGKNVLHPIGWDAFGLPAEQYAIDTGNDPEEFTALNIANFTRQIKSLGFSYDWDR  122
            R KR QG NVLHP+GWDAFGLPAEQYA+DTGNDP EFTA NIANF RQI++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EINTTDPEYYKWTQWIFEKLYEKGLAYEAEIAVNWCPALGTVLANEEVI-DGKSERGGFP  181
            E+NTTDP+YYKWTQWIF KLYEKGLAYEAE++VNW   LGT +ANEEV+ DG SERGG+P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VFRKPMRQWMLKITAYAdrllddldlvdWPENIKDMQRNWIGRSEGAEVTFKIKDSDETF  241
            V RKPMRQWMLKITAYA+RLL+DL+ VDWPE+IKDMQRNWIG+S GA+VTFK+KD+D  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  NVFTTRPDTLFGATYTVFAPEHELIEKITTPEQKEAVEAYKKQVELKSELERTDLAKDKT  301
             VFTTRPDTLFGATY+V+APEH L++ ITT++Q EAV  YK+Q  LKS+L RTDLAK+KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAINPINGEEVPIWIADYVLIQYGTGAIMAVPAHDERDFEFAQQFGLNIRPVLE  361
            GV TG+YAINP+NG E+P+WIADYVL  YGTGAIMAVPAHDERD EFA+QF L+I PVLE
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGDVTKEAFTGDGPHINSDFLNGLAKAEAITAAIDWLEKEGIGSRKITYRLRDWLFSRQR  421
            GG+V   AFT DG HINSDFL+GL KA AI+  ++WLE EG+G+ ++TYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPVIHWEDGettlvpedelplllpKATEIKPSGTGESPLANLHDWVNVTDKNGRK  481
            YWGEPIP+IHWEDG +T VPE ELPL+LP + +I+PSGTGESPLAN+ DW++VT  +G K
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  482  GRRETNTMPQWAGSSWYFLRYIDPNNSEAIADKEKLAEWLPVDVYIGGAEHAVLHLLYAR  541
            GRRETNTMPQWAGSSWY+LRYIDP+N+E +AD E L +WLPVD+Y+GGAEHAVLHLLYAR
Sbjct  484  GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYAR  543

Query  542  FWHKFLYDIGVVPTKEPFQKLFNQGMILG-------------------------------  570
            FWHK LYD+GVVPTKEPFQKLFNQGMILG                               
Sbjct  544  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEE  603

Query  571  --ENNEKMSKSRGNVVNPDEVVEKYGADTLRLYEMFMGPLEASIAWNENGLEGARKFLDR  628
              +   KMSKS  NVVNPD+VVE+YGADTLR+YEMFMGPL+ASIAW+E+GLEG+RKFLDR
Sbjct  604  LEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR  663

Query  629  IWRLLVTEEGTLAEKVTTDANANLEKAYHHMVKTVTNHYENLRFNTGISQLMIFINEAYK  688
            + RL+ T E      +T + ++ L+K Y++ VK+VT++ ++++FNT+I+QLM+F+N A K
Sbjct  664  VYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANK  717

Query  689  QDTIPKQYVEGFVQLLSPIAPHLAEELWEIL-GHTETISYVAWPTYDETKLVEDEVEIVL  747
            +D +  +Y  GFVQL++P+APHL+EELW+ L +  E+ISYV+WP+YDE+KLVE++VEIV+
Sbjct  718  EDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVV  777

Query  748  QVNGKVKSKITVAKSLEKEELEKIAQEDNKMKENLEGKTIRKVIVVPGKLVNIVAN  803
            Q++GKVK+K+ VAK L +EEL+ +A  ++K++ ++ GK I KVI VP KLVNIV +
Sbjct  778  QIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

152) leuS in NC_011660


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  945 bits (3582),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 564/836 (68%), Positives = 694/836 (84%), Gaps = 41/836 (4%)

Query  3    FNHKKMEPKWQQYWSEHNTFKTTEDKNKENFYALDMFPYPSGAGLHVGHPEGYTATDILS  62
            ++H  +EPKWQ +W++++TFKT  D +K +FYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMKRMQGKNVLHPIGWDAFGLPAEQYAIDTGNDPEEFTALNIANFTRQIKSLGFSYDWDR  122
            R KR QG NVLHP+GWDAFGLPAEQYA+DTGNDP EFTA NIANF RQI++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EINTTDPEYYKWTQWIFEKLYENGLAYEAEIAVNWCPALGTVLANEEVI-DGKSERGGFP  181
            E+NTTDP+YYKWTQWIF KLYE+GLAYEAE++VNW   LGT +ANEEV+ DG SERGG+P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VFRKPMRQWMLKITAYAdrllddldlvdWPENIKDMQRNWIGRSEGAEVTFKIKDSDETF  241
            V RKPMRQWMLKITAYA+RLL+DL+ VDWPE+IKDMQRNWIG+S GA+VTFK+KD+D  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  NVFTTRPDTLFGATYTVFAPEHELIEKITTPEQKEAVEAYKKQVELKSELERTDLAKDKT  301
             VFTTRPDTLFGATY+V+APEH L++ ITT++Q EAV  YK+Q  LKS+L RTDLAK+KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAINPINGEEVPIWIADYVLIQYGTGAIMAVPAHDERDFEFAQQFGLNIRPVLE  361
            GV TG+YAINP+NG E+P+WIADYVL  YGTGAIMAVPAHDERD EFA+QF L+I PVLE
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGDVTKEAFTGDGPHINSDFLNGLAKAEAITAAIDWLEKEGIGSRKITYRLRDWLFSRQR  421
            GG+V   AFT DG HINSDFL+GL KA AI+  ++WLE EG+G+ ++TYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPVIHWEDGettlvpedelplllpKATEIKPSGTGESPLANLHDWVNVTDENGRK  481
            YWGEPIP+IHWEDG +T VPE ELPL+LP + +I+PSGTGESPLAN+ DW++VT E+G K
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  482  GRRETNTMPQWAGSSWYFLRYIDPKNSEAIADKEKLAEWLPVDVYIGGAEHAVLHLLYAR  541
            GRRETNTMPQWAGSSWY+LRYIDP N+E +AD E L +WLPVD+Y+GGAEHAVLHLLYAR
Sbjct  484  GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYAR  543

Query  542  FWHKFLYDIGVVPTKEPFQKLFNQGMILG-------------------------------  570
            FWHK LYD+GVVPTKEPFQKLFNQGMILG                               
Sbjct  544  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEE  603

Query  571  --ENNEKMSKSRGNVVNPDEVVEKYGADTLRLYEMFMGPLEASIAWNENGLEGARKFLDR  628
              +   KMSKS  NVVNPD+VVE+YGADTLR+YEMFMGPL+ASIAW+E+GLEG+RKFLDR
Sbjct  604  LEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR  663

Query  629  IWRLLVTEEGTLAEKVTTDANANLEKAYHHMVKTVTNHYENLRFNTGISQLMIFINEAYK  688
            + RL+ T E      +T + ++ L+K Y++ VK+VT++ ++++FNT+I+QLM+F+N A K
Sbjct  664  VYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANK  717

Query  689  QDTIPKQYVEGFVQLLSPIAPHLAEELWEIL-GHTETISYVAWPTYDETKLVEDEVEIVL  747
            +D +  +Y  GFVQL++P+APHL+EELW+ L +  E+ISYV+WP+YDE+KLVE++VEIV+
Sbjct  718  EDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVV  777

Query  748  QVNGKVKSKITVAKSLGKEELEKIAQEDNKMKENLEGKTIRKVIVVPGKLVNIVAN  803
            Q++GKVK+K+ VAK L++EEL+ +A  ++K++ ++ GK I KVI VP KLVNIV +
Sbjct  778  QIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

153) LM220_15800 in NC_021830


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  945 bits (3581),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 564/836 (68%), Positives = 693/836 (83%), Gaps = 41/836 (4%)

Query  6    FNHKKMEPKWQQYWSEHNTFKTTEDKNKDNFYALDMFPYPSGAGLHVGHPEGYTATDILS  65
            ++H  +EPKWQ +W++++TFKT  D +K +FYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  66   RMKRMQGKNVLHPIGWDAFGLPAEQYAIDTGNDPEEFTALNIANFTRQIKSLGFSYDWDR  125
            R KR QG NVLHP+GWDAFGLPAEQYA+DTGNDP EFTA NIANF RQI++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  126  EINTTDPEYYKWTQWIFEKLYEKGLAYEAEIAVNWCPALGTVLANEEVI-DGKSERGGFP  184
            E+NTTDP+YYKWTQWIF KLYEKGLAYEAE++VNW   LGT +ANEEV+ DG SERGG+P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  185  VFRKPMRQWMLKITAYAdrllddldlvdWPENIKDMQRNWIGRSEGAEVTFKIKDSDETF  244
            V RKPMRQWMLKITAYA+RLL+DL+ VDWPE+IKDMQRNWIG+S GA+VTFK+KD+D  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  245  NVFTTRPDTLFGATYTVFAPEHELIEKITTPEQKEAVEAYKKQVELKSELERTDLAKDKT  304
             VFTTRPDTLFGATY+V+APEH L++ ITT++Q EAV  YK+Q  LKS+L RTDLAK+KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  305  GVFTGAYAINPINGEEVPIWIADYVLIQYGTGAIMAVPAHDERDFEFAQQFGLNIRPVLE  364
            GV TG+YAINP+NG E+P+WIADYVL  YGTGAIMAVPAHDERD EFA+QF L+I PVLE
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  365  GGDVTKEAFTGDGPHINSDFLNGLAKAEAITAAIDWLEKEGIGSRKITYRLRDWLFSRQR  424
            GG+V   AFT DG HINSDFL+GL KA AI+  ++WLE EG+G+ ++TYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  425  YWGEPIPVIHWEDGettlvpedelplllpKATEIKPSGTGESPLANLHDWVNVTDKNGRK  484
            YWGEPIP+IHWEDG +T VPE ELPL+LP + +I+PSGTGESPLAN+ DW++VT  +G K
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  485  GRRETNTMPQWAGSSWYFLRYIDPNNSEAIADKEKLAEWLPVDVYIGGAEHAVLHLLYAR  544
            GRRETNTMPQWAGSSWY+LRYIDP+N+E +AD E L +WLPVD+Y+GGAEHAVLHLLYAR
Sbjct  484  GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYAR  543

Query  545  FWHKFLYDIGVVPTKEPFQKLFNQGMILG-------------------------------  573
            FWHK LYD+GVVPTKEPFQKLFNQGMILG                               
Sbjct  544  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEE  603

Query  574  --ENNEKMSKSRGNVVNPDEVVEKYGADTLRLYEMFMGPLEASIAWNENGLEGARKFLDR  631
              +   KMSKS  NVVNPD+VVE+YGADTLR+YEMFMGPL+ASIAW+E+GLEG+RKFLDR
Sbjct  604  LEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR  663

Query  632  IWRLLVTEEGTLAEKVTTDANANLEKAYHHMVKTVTNHYENLRFNTGISQLMIFINEAYK  691
            + RL+ T E      +T + ++ L+K Y++ VK+VT++ ++++FNT+I+QLM+F+N A K
Sbjct  664  VYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANK  717

Query  692  QDTIPKQYVEGFVQLLSPIAPHLAEELWEIL-GHTETISYVAWPTYDETKLVEDEVEIVL  750
            +D +  +Y  GFVQL++P+APHL+EELW+ L +  E+ISYV+WP+YDE+KLVE++VEIV+
Sbjct  718  EDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVV  777

Query  751  QVNGKVKSKITVAKSLEKEELEKIAQEDNKMKENLEGKTIRKVIVVPGKLVNIVAN  806
            Q++GKVK+K+ VAK L +EEL+ +A  ++K++ ++ GK I KVI VP KLVNIV +
Sbjct  778  QIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

154) leuS in NC_018642


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  945 bits (3581),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 564/836 (68%), Positives = 693/836 (83%), Gaps = 41/836 (4%)

Query  6    FNHKKMEPKWQQYWSEHNTFKTTEDKNKDNFYALDMFPYPSGAGLHVGHPEGYTATDILS  65
            ++H  +EPKWQ +W++++TFKT  D +K +FYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  66   RMKRMQGKNVLHPIGWDAFGLPAEQYAIDTGNDPEEFTALNIANFTRQIKSLGFSYDWDR  125
            R KR QG NVLHP+GWDAFGLPAEQYA+DTGNDP EFTA NIANF RQI++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  126  EINTTDPEYYKWTQWIFEKLYEKGLAYEAEIAVNWCPALGTVLANEEVI-DGKSERGGFP  184
            E+NTTDP+YYKWTQWIF KLYEKGLAYEAE++VNW   LGT +ANEEV+ DG SERGG+P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  185  VFRKPMRQWMLKITAYAdrllddldlvdWPENIKDMQRNWIGRSEGAEVTFKIKDSDETF  244
            V RKPMRQWMLKITAYA+RLL+DL+ VDWPE+IKDMQRNWIG+S GA+VTFK+KD+D  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  245  NVFTTRPDTLFGATYTVFAPEHELIEKITTPEQKEAVEAYKKQVELKSELERTDLAKDKT  304
             VFTTRPDTLFGATY+V+APEH L++ ITT++Q EAV  YK+Q  LKS+L RTDLAK+KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  305  GVFTGAYAINPINGEEVPIWIADYVLIQYGTGAIMAVPAHDERDFEFAQQFGLNIRPVLE  364
            GV TG+YAINP+NG E+P+WIADYVL  YGTGAIMAVPAHDERD EFA+QF L+I PVLE
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  365  GGDVTKEAFTGDGPHINSDFLNGLAKAEAITAAIDWLEKEGIGSRKITYRLRDWLFSRQR  424
            GG+V   AFT DG HINSDFL+GL KA AI+  ++WLE EG+G+ ++TYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  425  YWGEPIPVIHWEDGettlvpedelplllpKATEIKPSGTGESPLANLHDWVNVTDKNGRK  484
            YWGEPIP+IHWEDG +T VPE ELPL+LP + +I+PSGTGESPLAN+ DW++VT  +G K
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  485  GRRETNTMPQWAGSSWYFLRYIDPNNSEAIADKEKLAEWLPVDVYIGGAEHAVLHLLYAR  544
            GRRETNTMPQWAGSSWY+LRYIDP+N+E +AD E L +WLPVD+Y+GGAEHAVLHLLYAR
Sbjct  484  GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYAR  543

Query  545  FWHKFLYDIGVVPTKEPFQKLFNQGMILG-------------------------------  573
            FWHK LYD+GVVPTKEPFQKLFNQGMILG                               
Sbjct  544  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEE  603

Query  574  --ENNEKMSKSRGNVVNPDEVVEKYGADTLRLYEMFMGPLEASIAWNENGLEGARKFLDR  631
              +   KMSKS  NVVNPD+VVE+YGADTLR+YEMFMGPL+ASIAW+E+GLEG+RKFLDR
Sbjct  604  LEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR  663

Query  632  IWRLLVTEEGTLAEKVTTDANANLEKAYHHMVKTVTNHYENLRFNTGISQLMIFINEAYK  691
            + RL+ T E      +T + ++ L+K Y++ VK+VT++ ++++FNT+I+QLM+F+N A K
Sbjct  664  VYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANK  717

Query  692  QDTIPKQYVEGFVQLLSPIAPHLAEELWEIL-GHTETISYVAWPTYDETKLVEDEVEIVL  750
            +D +  +Y  GFVQL++P+APHL+EELW+ L +  E+ISYV+WP+YDE+KLVE++VEIV+
Sbjct  718  EDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVV  777

Query  751  QVNGKVKSKITVAKSLEKEELEKIAQEDNKMKENLEGKTIRKVIVVPGKLVNIVAN  806
            Q++GKVK+K+ VAK L +EEL+ +A  ++K++ ++ GK I KVI VP KLVNIV +
Sbjct  778  QIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

155) leuS in NC_017537


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  945 bits (3582),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 564/836 (68%), Positives = 694/836 (84%), Gaps = 41/836 (4%)

Query  3    FNHKKMEPKWQQYWSEHNTFKTTEDKNKENFYALDMFPYPSGAGLHVGHPEGYTATDILS  62
            ++H  +EPKWQ +W++++TFKT  D +K +FYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMKRMQGKNVLHPIGWDAFGLPAEQYAIDTGNDPEEFTALNIANFTRQIKSLGFSYDWDR  122
            R KR QG NVLHP+GWDAFGLPAEQYA+DTGNDP EFTA NIANF RQI++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EINTTDPEYYKWTQWIFEKLYENGLAYEAEIAVNWCPALGTVLANEEVI-DGKSERGGFP  181
            E+NTTDP+YYKWTQWIF KLYE+GLAYEAE++VNW   LGT +ANEEV+ DG SERGG+P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VFRKPMRQWMLKITAYAdrllddldlvdWPENIKDMQRNWIGRSEGAEVTFKIKDSDETF  241
            V RKPMRQWMLKITAYA+RLL+DL+ VDWPE+IKDMQRNWIG+S GA+VTFK+KD+D  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  NVFTTRPDTLFGATYTVFAPEHELIEKITTPEQKEAVEAYKKQVELKSELERTDLAKDKT  301
             VFTTRPDTLFGATY+V+APEH L++ ITT++Q EAV  YK+Q  LKS+L RTDLAK+KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAINPINGEEVPIWIADYVLIQYGTGAIMAVPAHDERDFEFAQQFGLNIRPVLE  361
            GV TG+YAINP+NG E+P+WIADYVL  YGTGAIMAVPAHDERD EFA+QF L+I PVLE
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGDVTKEAFTGDGPHINSDFLNGLAKAEAITAAIDWLEKEGIGSRKITYRLRDWLFSRQR  421
            GG+V   AFT DG HINSDFL+GL KA AI+  ++WLE EG+G+ ++TYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPVIHWEDGettlvpedelplllpKATEIKPSGTGESPLANLHDWVNVTDENGRK  481
            YWGEPIP+IHWEDG +T VPE ELPL+LP + +I+PSGTGESPLAN+ DW++VT E+G K
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  482  GRRETNTMPQWAGSSWYFLRYIDPKNSEAIADKEKLAEWLPVDVYIGGAEHAVLHLLYAR  541
            GRRETNTMPQWAGSSWY+LRYIDP N+E +AD E L +WLPVD+Y+GGAEHAVLHLLYAR
Sbjct  484  GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYAR  543

Query  542  FWHKFLYDIGVVPTKEPFQKLFNQGMILG-------------------------------  570
            FWHK LYD+GVVPTKEPFQKLFNQGMILG                               
Sbjct  544  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEE  603

Query  571  --ENNEKMSKSRGNVVNPDEVVEKYGADTLRLYEMFMGPLEASIAWNENGLEGARKFLDR  628
              +   KMSKS  NVVNPD+VVE+YGADTLR+YEMFMGPL+ASIAW+E+GLEG+RKFLDR
Sbjct  604  LEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR  663

Query  629  IWRLLVTEEGTLAEKVTTDANANLEKAYHHMVKTVTNHYENLRFNTGISQLMIFINEAYK  688
            + RL+ T E      +T + ++ L+K Y++ VK+VT++ ++++FNT+I+QLM+F+N A K
Sbjct  664  VYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANK  717

Query  689  QDTIPKQYVEGFVQLLSPIAPHLAEELWEIL-GHTETISYVAWPTYDETKLVEDEVEIVL  747
            +D +  +Y  GFVQL++P+APHL+EELW+ L +  E+ISYV+WP+YDE+KLVE++VEIV+
Sbjct  718  EDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVV  777

Query  748  QVNGKVKSKITVAKSLGKEELEKIAQEDNKMKENLEGKTIRKVIVVPGKLVNIVAN  803
            Q++GKVK+K+ VAK L++EEL+ +A  ++K++ ++ GK I KVI VP KLVNIV +
Sbjct  778  QIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

156) leuS in NC_018587


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  945 bits (3581),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 564/836 (68%), Positives = 693/836 (83%), Gaps = 41/836 (4%)

Query  6    FNHKKMEPKWQQYWSEHNTFKTTEDKNKDNFYALDMFPYPSGAGLHVGHPEGYTATDILS  65
            ++H  +EPKWQ +W++++TFKT  D +K +FYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  66   RMKRMQGKNVLHPIGWDAFGLPAEQYAIDTGNDPEEFTALNIANFTRQIKSLGFSYDWDR  125
            R KR QG NVLHP+GWDAFGLPAEQYA+DTGNDP EFTA NIANF RQI++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  126  EINTTDPEYYKWTQWIFEKLYEKGLAYEAEIAVNWCPALGTVLANEEVI-DGKSERGGFP  184
            E+NTTDP+YYKWTQWIF KLYEKGLAYEAE++VNW   LGT +ANEEV+ DG SERGG+P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  185  VFRKPMRQWMLKITAYAdrllddldlvdWPENIKDMQRNWIGRSEGAEVTFKIKDSDETF  244
            V RKPMRQWMLKITAYA+RLL+DL+ VDWPE+IKDMQRNWIG+S GA+VTFK+KD+D  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  245  NVFTTRPDTLFGATYTVFAPEHELIEKITTPEQKEAVEAYKKQVELKSELERTDLAKDKT  304
             VFTTRPDTLFGATY+V+APEH L++ ITT++Q EAV  YK+Q  LKS+L RTDLAK+KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  305  GVFTGAYAINPINGEEVPIWIADYVLIQYGTGAIMAVPAHDERDFEFAQQFGLNIRPVLE  364
            GV TG+YAINP+NG E+P+WIADYVL  YGTGAIMAVPAHDERD EFA+QF L+I PVLE
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  365  GGDVTKEAFTGDGPHINSDFLNGLAKAEAITAAIDWLEKEGIGSRKITYRLRDWLFSRQR  424
            GG+V   AFT DG HINSDFL+GL KA AI+  ++WLE EG+G+ ++TYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  425  YWGEPIPVIHWEDGettlvpedelplllpKATEIKPSGTGESPLANLHDWVNVTDKNGRK  484
            YWGEPIP+IHWEDG +T VPE ELPL+LP + +I+PSGTGESPLAN+ DW++VT  +G K
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  485  GRRETNTMPQWAGSSWYFLRYIDPNNSEAIADKEKLAEWLPVDVYIGGAEHAVLHLLYAR  544
            GRRETNTMPQWAGSSWY+LRYIDP+N+E +AD E L +WLPVD+Y+GGAEHAVLHLLYAR
Sbjct  484  GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYAR  543

Query  545  FWHKFLYDIGVVPTKEPFQKLFNQGMILG-------------------------------  573
            FWHK LYD+GVVPTKEPFQKLFNQGMILG                               
Sbjct  544  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEE  603

Query  574  --ENNEKMSKSRGNVVNPDEVVEKYGADTLRLYEMFMGPLEASIAWNENGLEGARKFLDR  631
              +   KMSKS  NVVNPD+VVE+YGADTLR+YEMFMGPL+ASIAW+E+GLEG+RKFLDR
Sbjct  604  LEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR  663

Query  632  IWRLLVTEEGTLAEKVTTDANANLEKAYHHMVKTVTNHYENLRFNTGISQLMIFINEAYK  691
            + RL+ T E      +T + ++ L+K Y++ VK+VT++ ++++FNT+I+QLM+F+N A K
Sbjct  664  VYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANK  717

Query  692  QDTIPKQYVEGFVQLLSPIAPHLAEELWEIL-GHTETISYVAWPTYDETKLVEDEVEIVL  750
            +D +  +Y  GFVQL++P+APHL+EELW+ L +  E+ISYV+WP+YDE+KLVE++VEIV+
Sbjct  718  EDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVV  777

Query  751  QVNGKVKSKITVAKSLEKEELEKIAQEDNKMKENLEGKTIRKVIVVPGKLVNIVAN  806
            Q++GKVK+K+ VAK L +EEL+ +A  ++K++ ++ GK I KVI VP KLVNIV +
Sbjct  778  QIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

157) leuS in NC_017529


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  945 bits (3582),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 564/836 (68%), Positives = 694/836 (84%), Gaps = 41/836 (4%)

Query  6    FNHKKMEPKWQQYWSEHNTFKTTEDKNKENFYALDMFPYPSGAGLHVGHPEGYTATDILS  65
            ++H  +EPKWQ +W++++TFKT  D +K +FYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  66   RMKRMQGKNVLHPIGWDAFGLPAEQYAIDTGNDPEEFTALNIANFTRQIKSLGFSYDWDR  125
            R KR QG NVLHP+GWDAFGLPAEQYA+DTGNDP EFTA NIANF RQI++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  126  EINTTDPEYYKWTQWIFEKLYENGLAYEAEIAVNWCPALGTVLANEEVI-DGKSERGGFP  184
            E+NTTDP+YYKWTQWIF KLYE+GLAYEAE++VNW   LGT +ANEEV+ DG SERGG+P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  185  VFRKPMRQWMLKITAYAdrllddldlvdWPENIKDMQRNWIGRSEGAEVTFKIKDSDETF  244
            V RKPMRQWMLKITAYA+RLL+DL+ VDWPE+IKDMQRNWIG+S GA+VTFK+KD+D  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  245  NVFTTRPDTLFGATYTVFAPEHELIEKITTPEQKEAVEAYKKQVELKSELERTDLAKDKT  304
             VFTTRPDTLFGATY+V+APEH L++ ITT++Q EAV  YK+Q  LKS+L RTDLAK+KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  305  GVFTGAYAINPINGEEVPIWIADYVLIQYGTGAIMAVPAHDERDFEFAQQFGLNIRPVLE  364
            GV TG+YAINP+NG E+P+WIADYVL  YGTGAIMAVPAHDERD EFA+QF L+I PVLE
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  365  GGDVTKEAFTGDGPHINSDFLNGLAKAEAITAAIDWLEKEGIGSRKITYRLRDWLFSRQR  424
            GG+V   AFT DG HINSDFL+GL KA AI+  ++WLE EG+G+ ++TYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  425  YWGEPIPVIHWEDGettlvpedelplllpKATEIKPSGTGESPLANLHDWVNVTDENGRK  484
            YWGEPIP+IHWEDG +T VPE ELPL+LP + +I+PSGTGESPLAN+ DW++VT E+G K
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  485  GRRETNTMPQWAGSSWYFLRYIDPKNSEAIADKEKLAEWLPVDVYIGGAEHAVLHLLYAR  544
            GRRETNTMPQWAGSSWY+LRYIDP N+E +AD E L +WLPVD+Y+GGAEHAVLHLLYAR
Sbjct  484  GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYAR  543

Query  545  FWHKFLYDIGVVPTKEPFQKLFNQGMILG-------------------------------  573
            FWHK LYD+GVVPTKEPFQKLFNQGMILG                               
Sbjct  544  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEE  603

Query  574  --ENNEKMSKSRGNVVNPDEVVEKYGADTLRLYEMFMGPLEASIAWNENGLEGARKFLDR  631
              +   KMSKS  NVVNPD+VVE+YGADTLR+YEMFMGPL+ASIAW+E+GLEG+RKFLDR
Sbjct  604  LEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR  663

Query  632  IWRLLVTEEGTLAEKVTTDANANLEKAYHHMVKTVTNHYENLRFNTGISQLMIFINEAYK  691
            + RL+ T E      +T + ++ L+K Y++ VK+VT++ ++++FNT+I+QLM+F+N A K
Sbjct  664  VYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANK  717

Query  692  QDTIPKQYVEGFVQLLSPIAPHLAEELWEIL-GHTETISYVAWPTYDETKLVEDEVEIVL  750
            +D +  +Y  GFVQL++P+APHL+EELW+ L +  E+ISYV+WP+YDE+KLVE++VEIV+
Sbjct  718  EDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVV  777

Query  751  QVNGKVKSKITVAKSLGKEELEKIAQEDNKMKENLEGKTIRKVIVVPGKLVNIVAN  806
            Q++GKVK+K+ VAK L++EEL+ +A  ++K++ ++ GK I KVI VP KLVNIV +
Sbjct  778  QIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

158) leuS in NC_002973


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  945 bits (3579),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 564/836 (68%), Positives = 693/836 (83%), Gaps = 41/836 (4%)

Query  3    FNHKKMEPKWQQYWSEHNTFKTTEDKNKDNFYALDMFPYPSGAGLHVGHPEGYTATDILS  62
            ++H  +EPKWQ +W++++TFKT  D +K +FYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMKRMQGKNVLHPIGWDAFGLPAEQYAIDTGNDPEEFTALNIANFTRQIKSLGFSYDWDR  122
            R KR QG NVLHP+GWDAFGLPAEQYA+DTGNDP EFTA NIANF RQI++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EINTTDPEYYKWTQWIFEKLYEKGLAYEAEIAVNWCPALGTVLANEEVI-DGKSERGGFP  181
            E+NTTDP+YYKWTQWIF KLYEKGLAYEAE++VNW   LGT +ANEEV+ DG SERGG+P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VFRKPMRQWMLKITAYAdrllddldlvdWPENIKDMQRNWIGRSEGAEVTFKIKDSDETF  241
            V RKPMRQWMLKITAYA+RLL+DL+ VDWPE+IKDMQRNWIG+S GA+VTFK+KD+D  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  NVFTTRPDTLFGATYTVFAPEHELIEKITTPEQKEAVEAYKKQVELKSELERTDLAKDKT  301
             VFTTRPDTLFGATY+V+APEH L++ ITT++Q EAV  YK+Q  LKS+L RTDLAK+KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAINPINGEEVPIWIADYVLIQYGTGAIMAVPAHDERDFEFAQQFGLNIRPVLE  361
            GV TG+YAINP+NG E+P+WIADYVL  YGTGAIMAVPAHDERD EFA+QF L+I PVLE
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGDVTKEAFTGDGPHINSDFLNGLAKAEAITAAIDWLEKEGIGSRKITYRLRDWLFSRQR  421
            GG+V   AFT DG HINSDFL+GL KA AI+  ++WLE EG+G+ ++TYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPVIHWEDGettlvpedelplllpKATEIKPSGTGESPLANLHDWVNVTDKNGRK  481
            YWGEPIP+IHWEDG +T VPE ELPL+LP + +I+PSGTGESPLAN+ DW++VT  +G K
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  482  GRRETNTMPQWAGSSWYFLRYIDPNNSEAIADKEKLAEWLPVDVYIGGAEHAVLHLLYAR  541
            GRRETNTMPQWAGSSWY+LRYIDP+N+E +AD E L +WLPVD+Y+GGAEHAVLHLLYAR
Sbjct  484  GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYAR  543

Query  542  FWHKFLYDIGVVPTKEPFQKLFNQGMILG-------------------------------  570
            FWHK LYD+GVVPTKEPFQKLFNQGMILG                               
Sbjct  544  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEE  603

Query  571  --ENNEKMSKSRGNVVNPDEVVEKYGADTLRLYEMFMGPLEASIAWNENGLEGARKFLDR  628
              +   KMSKS  NVVNPD+VVE+YGADTLR+YEMFMGPL+ASIAW+E+GLEG+RKFLDR
Sbjct  604  LEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR  663

Query  629  IWRLLVTEEGTLAEKVTTDANANLEKAYHHMVKTVTNHYENLRFNTGISQLMIFINEAYK  688
            + RL+ T E      +T + ++ L+K Y++ VK+VT++ ++++FNT+I+QLM+F+N A K
Sbjct  664  VYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANK  717

Query  689  QDTIPKQYVEGFVQLLSPIAPHLAEELWEIL-GHTETISYVAWPTYDETKLVEDEVEIVL  747
            +D +  +Y  GFVQL++P+APHL+EELW+ L +  E+ISYV+WP+YDE+KLVE++VEIV+
Sbjct  718  EDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVV  777

Query  748  QVNGKVKSKITVAKSLEKEELEKIAQEDNKMKENLEGKTIRKVIVVPGKLVNIVAN  803
            Q++GKVK+K+ VAK L +EEL+ +A  ++K++ ++ GK I KVI VP KLVNIV +
Sbjct  778  QIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

159) leuS in NC_019556


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  945 bits (3581),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 564/836 (68%), Positives = 693/836 (83%), Gaps = 41/836 (4%)

Query  50   FNHKKMEPKWQQYWSEHNTFKTTEDKNKDNFYALDMFPYPSGAGLHVGHPEGYTATDILS  109
            ++H  +EPKWQ +W++++TFKT  D +K +FYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  110  RMKRMQGKNVLHPIGWDAFGLPAEQYAIDTGNDPEEFTALNIANFTRQIKSLGFSYDWDR  169
            R KR QG NVLHP+GWDAFGLPAEQYA+DTGNDP EFTA NIANF RQI++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  170  EINTTDPEYYKWTQWIFEKLYEKGLAYEAEIAVNWCPALGTVLANEEVI-DGKSERGGFP  228
            E+NTTDP+YYKWTQWIF KLYEKGLAYEAE++VNW   LGT +ANEEV+ DG SERGG+P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  229  VFRKPMRQWMLKITAYAdrllddldlvdWPENIKDMQRNWIGRSEGAEVTFKIKDSDETF  288
            V RKPMRQWMLKITAYA+RLL+DL+ VDWPE+IKDMQRNWIG+S GA+VTFK+KD+D  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  289  NVFTTRPDTLFGATYTVFAPEHELIEKITTPEQKEAVEAYKKQVELKSELERTDLAKDKT  348
             VFTTRPDTLFGATY+V+APEH L++ ITT++Q EAV  YK+Q  LKS+L RTDLAK+KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  349  GVFTGAYAINPINGEEVPIWIADYVLIQYGTGAIMAVPAHDERDFEFAQQFGLNIRPVLE  408
            GV TG+YAINP+NG E+P+WIADYVL  YGTGAIMAVPAHDERD EFA+QF L+I PVLE
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  409  GGDVTKEAFTGDGPHINSDFLNGLAKAEAITAAIDWLEKEGIGSRKITYRLRDWLFSRQR  468
            GG+V   AFT DG HINSDFL+GL KA AI+  ++WLE EG+G+ ++TYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  469  YWGEPIPVIHWEDGettlvpedelplllpKATEIKPSGTGESPLANLHDWVNVTDKNGRK  528
            YWGEPIP+IHWEDG +T VPE ELPL+LP + +I+PSGTGESPLAN+ DW++VT  +G K
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  529  GRRETNTMPQWAGSSWYFLRYIDPNNSEAIADKEKLAEWLPVDVYIGGAEHAVLHLLYAR  588
            GRRETNTMPQWAGSSWY+LRYIDP+N+E +AD E L +WLPVD+Y+GGAEHAVLHLLYAR
Sbjct  484  GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYAR  543

Query  589  FWHKFLYDIGVVPTKEPFQKLFNQGMILG-------------------------------  617
            FWHK LYD+GVVPTKEPFQKLFNQGMILG                               
Sbjct  544  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEE  603

Query  618  --ENNEKMSKSRGNVVNPDEVVEKYGADTLRLYEMFMGPLEASIAWNENGLEGARKFLDR  675
              +   KMSKS  NVVNPD+VVE+YGADTLR+YEMFMGPL+ASIAW+E+GLEG+RKFLDR
Sbjct  604  LEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR  663

Query  676  IWRLLVTEEGTLAEKVTTDANANLEKAYHHMVKTVTNHYENLRFNTGISQLMIFINEAYK  735
            + RL+ T E      +T + ++ L+K Y++ VK+VT++ ++++FNT+I+QLM+F+N A K
Sbjct  664  VYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANK  717

Query  736  QDTIPKQYVEGFVQLLSPIAPHLAEELWEIL-GHTETISYVAWPTYDETKLVEDEVEIVL  794
            +D +  +Y  GFVQL++P+APHL+EELW+ L +  E+ISYV+WP+YDE+KLVE++VEIV+
Sbjct  718  EDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVV  777

Query  795  QVNGKVKSKITVAKSLEKEELEKIAQEDNKMKENLEGKTIRKVIVVPGKLVNIVAN  850
            Q++GKVK+K+ VAK L +EEL+ +A  ++K++ ++ GK I KVI VP KLVNIV +
Sbjct  778  QIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

160) leuS in NC_018591


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  945 bits (3581),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 564/836 (68%), Positives = 693/836 (83%), Gaps = 41/836 (4%)

Query  6    FNHKKMEPKWQQYWSEHNTFKTTEDKNKDNFYALDMFPYPSGAGLHVGHPEGYTATDILS  65
            ++H  +EPKWQ +W++++TFKT  D +K +FYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  66   RMKRMQGKNVLHPIGWDAFGLPAEQYAIDTGNDPEEFTALNIANFTRQIKSLGFSYDWDR  125
            R KR QG NVLHP+GWDAFGLPAEQYA+DTGNDP EFTA NIANF RQI++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  126  EINTTDPEYYKWTQWIFEKLYEKGLAYEAEIAVNWCPALGTVLANEEVI-DGKSERGGFP  184
            E+NTTDP+YYKWTQWIF KLYEKGLAYEAE++VNW   LGT +ANEEV+ DG SERGG+P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  185  VFRKPMRQWMLKITAYAdrllddldlvdWPENIKDMQRNWIGRSEGAEVTFKIKDSDETF  244
            V RKPMRQWMLKITAYA+RLL+DL+ VDWPE+IKDMQRNWIG+S GA+VTFK+KD+D  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  245  NVFTTRPDTLFGATYTVFAPEHELIEKITTPEQKEAVEAYKKQVELKSELERTDLAKDKT  304
             VFTTRPDTLFGATY+V+APEH L++ ITT++Q EAV  YK+Q  LKS+L RTDLAK+KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  305  GVFTGAYAINPINGEEVPIWIADYVLIQYGTGAIMAVPAHDERDFEFAQQFGLNIRPVLE  364
            GV TG+YAINP+NG E+P+WIADYVL  YGTGAIMAVPAHDERD EFA+QF L+I PVLE
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  365  GGDVTKEAFTGDGPHINSDFLNGLAKAEAITAAIDWLEKEGIGSRKITYRLRDWLFSRQR  424
            GG+V   AFT DG HINSDFL+GL KA AI+  ++WLE EG+G+ ++TYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  425  YWGEPIPVIHWEDGettlvpedelplllpKATEIKPSGTGESPLANLHDWVNVTDKNGRK  484
            YWGEPIP+IHWEDG +T VPE ELPL+LP + +I+PSGTGESPLAN+ DW++VT  +G K
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  485  GRRETNTMPQWAGSSWYFLRYIDPNNSEAIADKEKLAEWLPVDVYIGGAEHAVLHLLYAR  544
            GRRETNTMPQWAGSSWY+LRYIDP+N+E +AD E L +WLPVD+Y+GGAEHAVLHLLYAR
Sbjct  484  GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYAR  543

Query  545  FWHKFLYDIGVVPTKEPFQKLFNQGMILG-------------------------------  573
            FWHK LYD+GVVPTKEPFQKLFNQGMILG                               
Sbjct  544  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEE  603

Query  574  --ENNEKMSKSRGNVVNPDEVVEKYGADTLRLYEMFMGPLEASIAWNENGLEGARKFLDR  631
              +   KMSKS  NVVNPD+VVE+YGADTLR+YEMFMGPL+ASIAW+E+GLEG+RKFLDR
Sbjct  604  LEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR  663

Query  632  IWRLLVTEEGTLAEKVTTDANANLEKAYHHMVKTVTNHYENLRFNTGISQLMIFINEAYK  691
            + RL+ T E      +T + ++ L+K Y++ VK+VT++ ++++FNT+I+QLM+F+N A K
Sbjct  664  VYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANK  717

Query  692  QDTIPKQYVEGFVQLLSPIAPHLAEELWEIL-GHTETISYVAWPTYDETKLVEDEVEIVL  750
            +D +  +Y  GFVQL++P+APHL+EELW+ L +  E+ISYV+WP+YDE+KLVE++VEIV+
Sbjct  718  EDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVV  777

Query  751  QVNGKVKSKITVAKSLEKEELEKIAQEDNKMKENLEGKTIRKVIVVPGKLVNIVAN  806
            Q++GKVK+K+ VAK L +EEL+ +A  ++K++ ++ GK I KVI VP KLVNIV +
Sbjct  778  QIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

161) leuS in NC_018590


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  945 bits (3582),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 564/836 (68%), Positives = 694/836 (84%), Gaps = 41/836 (4%)

Query  6    FNHKKMEPKWQQYWSEHNTFKTTEDKNKENFYALDMFPYPSGAGLHVGHPEGYTATDILS  65
            ++H  +EPKWQ +W++++TFKT  D +K +FYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  66   RMKRMQGKNVLHPIGWDAFGLPAEQYAIDTGNDPEEFTALNIANFTRQIKSLGFSYDWDR  125
            R KR QG NVLHP+GWDAFGLPAEQYA+DTGNDP EFTA NIANF RQI++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  126  EINTTDPEYYKWTQWIFEKLYENGLAYEAEIAVNWCPALGTVLANEEVI-DGKSERGGFP  184
            E+NTTDP+YYKWTQWIF KLYE+GLAYEAE++VNW   LGT +ANEEV+ DG SERGG+P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  185  VFRKPMRQWMLKITAYAdrllddldlvdWPENIKDMQRNWIGRSEGAEVTFKIKDSDETF  244
            V RKPMRQWMLKITAYA+RLL+DL+ VDWPE+IKDMQRNWIG+S GA+VTFK+KD+D  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  245  NVFTTRPDTLFGATYTVFAPEHELIEKITTPEQKEAVEAYKKQVELKSELERTDLAKDKT  304
             VFTTRPDTLFGATY+V+APEH L++ ITT++Q EAV  YK+Q  LKS+L RTDLAK+KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  305  GVFTGAYAINPINGEEVPIWIADYVLIQYGTGAIMAVPAHDERDFEFAQQFGLNIRPVLE  364
            GV TG+YAINP+NG E+P+WIADYVL  YGTGAIMAVPAHDERD EFA+QF L+I PVLE
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  365  GGDVTKEAFTGDGPHINSDFLNGLAKAEAITAAIDWLEKEGIGSRKITYRLRDWLFSRQR  424
            GG+V   AFT DG HINSDFL+GL KA AI+  ++WLE EG+G+ ++TYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  425  YWGEPIPVIHWEDGettlvpedelplllpKATEIKPSGTGESPLANLHDWVNVTDENGRK  484
            YWGEPIP+IHWEDG +T VPE ELPL+LP + +I+PSGTGESPLAN+ DW++VT E+G K
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  485  GRRETNTMPQWAGSSWYFLRYIDPKNSEAIADKEKLAEWLPVDVYIGGAEHAVLHLLYAR  544
            GRRETNTMPQWAGSSWY+LRYIDP N+E +AD E L +WLPVD+Y+GGAEHAVLHLLYAR
Sbjct  484  GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYAR  543

Query  545  FWHKFLYDIGVVPTKEPFQKLFNQGMILG-------------------------------  573
            FWHK LYD+GVVPTKEPFQKLFNQGMILG                               
Sbjct  544  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEE  603

Query  574  --ENNEKMSKSRGNVVNPDEVVEKYGADTLRLYEMFMGPLEASIAWNENGLEGARKFLDR  631
              +   KMSKS  NVVNPD+VVE+YGADTLR+YEMFMGPL+ASIAW+E+GLEG+RKFLDR
Sbjct  604  LEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR  663

Query  632  IWRLLVTEEGTLAEKVTTDANANLEKAYHHMVKTVTNHYENLRFNTGISQLMIFINEAYK  691
            + RL+ T E      +T + ++ L+K Y++ VK+VT++ ++++FNT+I+QLM+F+N A K
Sbjct  664  VYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANK  717

Query  692  QDTIPKQYVEGFVQLLSPIAPHLAEELWEIL-GHTETISYVAWPTYDETKLVEDEVEIVL  750
            +D +  +Y  GFVQL++P+APHL+EELW+ L +  E+ISYV+WP+YDE+KLVE++VEIV+
Sbjct  718  EDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVV  777

Query  751  QVNGKVKSKITVAKSLGKEELEKIAQEDNKMKENLEGKTIRKVIVVPGKLVNIVAN  806
            Q++GKVK+K+ VAK L++EEL+ +A  ++K++ ++ GK I KVI VP KLVNIV +
Sbjct  778  QIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

162) leuS in NC_018585


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  945 bits (3581),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 564/836 (68%), Positives = 693/836 (83%), Gaps = 41/836 (4%)

Query  6    FNHKKMEPKWQQYWSEHNTFKTTEDKNKDNFYALDMFPYPSGAGLHVGHPEGYTATDILS  65
            ++H  +EPKWQ +W++++TFKT  D +K +FYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  66   RMKRMQGKNVLHPIGWDAFGLPAEQYAIDTGNDPEEFTALNIANFTRQIKSLGFSYDWDR  125
            R KR QG NVLHP+GWDAFGLPAEQYA+DTGNDP EFTA NIANF RQI++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  126  EINTTDPEYYKWTQWIFEKLYEKGLAYEAEIAVNWCPALGTVLANEEVI-DGKSERGGFP  184
            E+NTTDP+YYKWTQWIF KLYEKGLAYEAE++VNW   LGT +ANEEV+ DG SERGG+P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  185  VFRKPMRQWMLKITAYAdrllddldlvdWPENIKDMQRNWIGRSEGAEVTFKIKDSDETF  244
            V RKPMRQWMLKITAYA+RLL+DL+ VDWPE+IKDMQRNWIG+S GA+VTFK+KD+D  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  245  NVFTTRPDTLFGATYTVFAPEHELIEKITTPEQKEAVEAYKKQVELKSELERTDLAKDKT  304
             VFTTRPDTLFGATY+V+APEH L++ ITT++Q EAV  YK+Q  LKS+L RTDLAK+KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  305  GVFTGAYAINPINGEEVPIWIADYVLIQYGTGAIMAVPAHDERDFEFAQQFGLNIRPVLE  364
            GV TG+YAINP+NG E+P+WIADYVL  YGTGAIMAVPAHDERD EFA+QF L+I PVLE
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  365  GGDVTKEAFTGDGPHINSDFLNGLAKAEAITAAIDWLEKEGIGSRKITYRLRDWLFSRQR  424
            GG+V   AFT DG HINSDFL+GL KA AI+  ++WLE EG+G+ ++TYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  425  YWGEPIPVIHWEDGettlvpedelplllpKATEIKPSGTGESPLANLHDWVNVTDKNGRK  484
            YWGEPIP+IHWEDG +T VPE ELPL+LP + +I+PSGTGESPLAN+ DW++VT  +G K
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  485  GRRETNTMPQWAGSSWYFLRYIDPNNSEAIADKEKLAEWLPVDVYIGGAEHAVLHLLYAR  544
            GRRETNTMPQWAGSSWY+LRYIDP+N+E +AD E L +WLPVD+Y+GGAEHAVLHLLYAR
Sbjct  484  GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYAR  543

Query  545  FWHKFLYDIGVVPTKEPFQKLFNQGMILG-------------------------------  573
            FWHK LYD+GVVPTKEPFQKLFNQGMILG                               
Sbjct  544  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEE  603

Query  574  --ENNEKMSKSRGNVVNPDEVVEKYGADTLRLYEMFMGPLEASIAWNENGLEGARKFLDR  631
              +   KMSKS  NVVNPD+VVE+YGADTLR+YEMFMGPL+ASIAW+E+GLEG+RKFLDR
Sbjct  604  LEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR  663

Query  632  IWRLLVTEEGTLAEKVTTDANANLEKAYHHMVKTVTNHYENLRFNTGISQLMIFINEAYK  691
            + RL+ T E      +T + ++ L+K Y++ VK+VT++ ++++FNT+I+QLM+F+N A K
Sbjct  664  VYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANK  717

Query  692  QDTIPKQYVEGFVQLLSPIAPHLAEELWEIL-GHTETISYVAWPTYDETKLVEDEVEIVL  750
            +D +  +Y  GFVQL++P+APHL+EELW+ L +  E+ISYV+WP+YDE+KLVE++VEIV+
Sbjct  718  EDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVV  777

Query  751  QVNGKVKSKITVAKSLEKEELEKIAQEDNKMKENLEGKTIRKVIVVPGKLVNIVAN  806
            Q++GKVK+K+ VAK L +EEL+ +A  ++K++ ++ GK I KVI VP KLVNIV +
Sbjct  778  QIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

163) leuS in NC_018592


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  945 bits (3579),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 565/836 (68%), Positives = 694/836 (84%), Gaps = 41/836 (4%)

Query  6    FNHKKMEPKWQQYWSEHNTFKTTEDKNKENFYALDMFPYPSGAGLHVGHPEGYTATDILS  65
            ++H  +EPKWQ +W++++TFKT  D +K +FYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  66   RMKRMQGKNVLHPIGWDAFGLPAEQYAIDTGNDPEEFTALNIANFTRQIKSLGFSYDWDR  125
            R KR QG NVLHP+GWDAFGLPAEQYA+DTGNDP EFTA NIANF RQI++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  126  EINTTDPEYYKWTQWIFEKLYEKGLAYEAEIAVNWCPALGTVLANEEVI-DGKSERGGFP  184
            E+NTTDP+YYKWTQWIF KLYEKGLAYEAE++VNW   LGT +ANEEV+ DG SERGG+P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  185  VFRKPMRQWMLKITAYAdrllddldlvdWPENIKDMQRNWIGRSEGAEVTFKIKDSDETF  244
            V RKPMRQWMLKITAYA+RLL+DL+ VDWPE+IKDMQRNWIG+S GA+VTFK+KD+D  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  245  NVFTTRPDTLFGATYTVFAPEHELIEKITTPEQKEAVEAYKKQVELKSELERTDLAKDKT  304
             VFTTRPDTLFGATY+V+APEH L++ ITT++Q EAV  YK+Q  LKS+L RTDLAK+KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  305  GVFTGAYAINPINGEEVPIWIADYVLIQYGTGAIMAVPAHDERDFEFAQQFGLNIRPVLE  364
            GV TG+YAINP+NG E+P+WIADYVL  YGTGAIMAVPAHDERD EFA+QF L+I PVLE
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  365  GGDVTKEAFTGDGPHINSDFLNGLAKAEAITAAIDWLEKEGIGSRKITYRLRDWLFSRQR  424
            GG+V   AFT DG HINSDFL+GL KA AI+  ++WLE EG+G+ ++TYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  425  YWGEPIPVIHWEDGettlvpeeelplllpkateIKPSGTGESPLANLHDWVNVTDENGRK  484
            YWGEPIP+IHWEDG +T VPE ELPL+LP + +I+PSGTGESPLAN+ DW++VT E+G K
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  485  GRRETNTMPQWAGSSWYFLRYIDPKNSEAIADKEKLAEWLPVDVYIGGAEHAVLHLLYAR  544
            GRRETNTMPQWAGSSWY+LRYIDP N+E +AD E L +WLPVD+Y+GGAEHAVLHLLYAR
Sbjct  484  GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYAR  543

Query  545  FWHKFLYDIGVVPTKEPFQKLFNQGMILG-------------------------------  573
            FWHK LYD+GVVPTKEPFQKLFNQGMILG                               
Sbjct  544  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEE  603

Query  574  --ENNEKMSKSRGNVVNPDEVVEKYGADTLRLYEMFMGPLEASIAWNENGLEGARKFLDR  631
              +   KMSKS  NVVNPD+VVE+YGADTLR+YEMFMGPL+ASIAW+E+GLEG+RKFLDR
Sbjct  604  LEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR  663

Query  632  IWRLLVTEEGTLAEKVTTDANANLEKAYHHMVKTVTNHYENLRFNTGISQLMIFINEAYK  691
            + RL+ T E      +T + ++ L+K Y++ VK+VT++ ++++FNT+I+QLM+F+N A K
Sbjct  664  VYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANK  717

Query  692  QDTIPKQYVEGFVQLLSPIAPHLAEELWEIL-GHTETISYVAWPTYDEAKLVEDEVEIVL  750
            +D +  +Y  GFVQL++P+APHL+EELW+ L +  E+ISYV+WP+YDE+KLVE++VEIV+
Sbjct  718  EDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVV  777

Query  751  QVNGKVKSKITVAKSLGKEELEKIAQEDNKMKENLEGKTIRKVIVVPGKLVNIVAN  806
            Q++GKVK+K+ VAK L++EEL+ +A  ++K++ ++ GK I KVI VP KLVNIV +
Sbjct  778  QIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

164) leuS in NC_018593


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  945 bits (3582),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 564/836 (68%), Positives = 694/836 (84%), Gaps = 41/836 (4%)

Query  6    FNHKKMEPKWQQYWSEHNTFKTTEDKNKENFYALDMFPYPSGAGLHVGHPEGYTATDILS  65
            ++H  +EPKWQ +W++++TFKT  D +K +FYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  66   RMKRMQGKNVLHPIGWDAFGLPAEQYAIDTGNDPEEFTALNIANFTRQIKSLGFSYDWDR  125
            R KR QG NVLHP+GWDAFGLPAEQYA+DTGNDP EFTA NIANF RQI++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  126  EINTTDPEYYKWTQWIFEKLYENGLAYEAEIAVNWCPALGTVLANEEVI-DGKSERGGFP  184
            E+NTTDP+YYKWTQWIF KLYE+GLAYEAE++VNW   LGT +ANEEV+ DG SERGG+P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  185  VFRKPMRQWMLKITAYAdrllddldlvdWPENIKDMQRNWIGRSEGAEVTFKIKDSDETF  244
            V RKPMRQWMLKITAYA+RLL+DL+ VDWPE+IKDMQRNWIG+S GA+VTFK+KD+D  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  245  NVFTTRPDTLFGATYTVFAPEHELIEKITTPEQKEAVEAYKKQVELKSELERTDLAKDKT  304
             VFTTRPDTLFGATY+V+APEH L++ ITT++Q EAV  YK+Q  LKS+L RTDLAK+KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  305  GVFTGAYAINPINGEEVPIWIADYVLIQYGTGAIMAVPAHDERDFEFAQQFGLNIRPVLE  364
            GV TG+YAINP+NG E+P+WIADYVL  YGTGAIMAVPAHDERD EFA+QF L+I PVLE
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  365  GGDVTKEAFTGDGPHINSDFLNGLAKAEAITAAIDWLEKEGIGSRKITYRLRDWLFSRQR  424
            GG+V   AFT DG HINSDFL+GL KA AI+  ++WLE EG+G+ ++TYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  425  YWGEPIPVIHWEDGettlvpedelplllpKATEIKPSGTGESPLANLHDWVNVTDENGRK  484
            YWGEPIP+IHWEDG +T VPE ELPL+LP + +I+PSGTGESPLAN+ DW++VT E+G K
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  485  GRRETNTMPQWAGSSWYFLRYIDPKNSEAIADKEKLAEWLPVDVYIGGAEHAVLHLLYAR  544
            GRRETNTMPQWAGSSWY+LRYIDP N+E +AD E L +WLPVD+Y+GGAEHAVLHLLYAR
Sbjct  484  GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYAR  543

Query  545  FWHKFLYDIGVVPTKEPFQKLFNQGMILG-------------------------------  573
            FWHK LYD+GVVPTKEPFQKLFNQGMILG                               
Sbjct  544  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEE  603

Query  574  --ENNEKMSKSRGNVVNPDEVVEKYGADTLRLYEMFMGPLEASIAWNENGLEGARKFLDR  631
              +   KMSKS  NVVNPD+VVE+YGADTLR+YEMFMGPL+ASIAW+E+GLEG+RKFLDR
Sbjct  604  LEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR  663

Query  632  IWRLLVTEEGTLAEKVTTDANANLEKAYHHMVKTVTNHYENLRFNTGISQLMIFINEAYK  691
            + RL+ T E      +T + ++ L+K Y++ VK+VT++ ++++FNT+I+QLM+F+N A K
Sbjct  664  VYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANK  717

Query  692  QDTIPKQYVEGFVQLLSPIAPHLAEELWEIL-GHTETISYVAWPTYDETKLVEDEVEIVL  750
            +D +  +Y  GFVQL++P+APHL+EELW+ L +  E+ISYV+WP+YDE+KLVE++VEIV+
Sbjct  718  EDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVV  777

Query  751  QVNGKVKSKITVAKSLGKEELEKIAQEDNKMKENLEGKTIRKVIVVPGKLVNIVAN  806
            Q++GKVK+K+ VAK L++EEL+ +A  ++K++ ++ GK I KVI VP KLVNIV +
Sbjct  778  QIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

165) M642_06250 in NC_021823


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  945 bits (3582),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 564/836 (68%), Positives = 694/836 (84%), Gaps = 41/836 (4%)

Query  6    FNHKKMEPKWQQYWSEHNTFKTTEDKNKENFYALDMFPYPSGAGLHVGHPEGYTATDILS  65
            ++H  +EPKWQ +W++++TFKT  D +K +FYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  66   RMKRMQGKNVLHPIGWDAFGLPAEQYAIDTGNDPEEFTALNIANFTRQIKSLGFSYDWDR  125
            R KR QG NVLHP+GWDAFGLPAEQYA+DTGNDP EFTA NIANF RQI++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  126  EINTTDPEYYKWTQWIFEKLYENGLAYEAEIAVNWCPALGTVLANEEVI-DGKSERGGFP  184
            E+NTTDP+YYKWTQWIF KLYE+GLAYEAE++VNW   LGT +ANEEV+ DG SERGG+P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  185  VFRKPMRQWMLKITAYAdrllddldlvdWPENIKDMQRNWIGRSEGAEVTFKIKDSDETF  244
            V RKPMRQWMLKITAYA+RLL+DL+ VDWPE+IKDMQRNWIG+S GA+VTFK+KD+D  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  245  NVFTTRPDTLFGATYTVFAPEHELIEKITTPEQKEAVEAYKKQVELKSELERTDLAKDKT  304
             VFTTRPDTLFGATY+V+APEH L++ ITT++Q EAV  YK+Q  LKS+L RTDLAK+KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  305  GVFTGAYAINPINGEEVPIWIADYVLIQYGTGAIMAVPAHDERDFEFAQQFGLNIRPVLE  364
            GV TG+YAINP+NG E+P+WIADYVL  YGTGAIMAVPAHDERD EFA+QF L+I PVLE
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  365  GGDVTKEAFTGDGPHINSDFLNGLAKAEAITAAIDWLEKEGIGSRKITYRLRDWLFSRQR  424
            GG+V   AFT DG HINSDFL+GL KA AI+  ++WLE EG+G+ ++TYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  425  YWGEPIPVIHWEDGettlvpedelplllpKATEIKPSGTGESPLANLHDWVNVTDENGRK  484
            YWGEPIP+IHWEDG +T VPE ELPL+LP + +I+PSGTGESPLAN+ DW++VT E+G K
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  485  GRRETNTMPQWAGSSWYFLRYIDPKNSEAIADKEKLAEWLPVDVYIGGAEHAVLHLLYAR  544
            GRRETNTMPQWAGSSWY+LRYIDP N+E +AD E L +WLPVD+Y+GGAEHAVLHLLYAR
Sbjct  484  GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYAR  543

Query  545  FWHKFLYDIGVVPTKEPFQKLFNQGMILG-------------------------------  573
            FWHK LYD+GVVPTKEPFQKLFNQGMILG                               
Sbjct  544  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEE  603

Query  574  --ENNEKMSKSRGNVVNPDEVVEKYGADTLRLYEMFMGPLEASIAWNENGLEGARKFLDR  631
              +   KMSKS  NVVNPD+VVE+YGADTLR+YEMFMGPL+ASIAW+E+GLEG+RKFLDR
Sbjct  604  LEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR  663

Query  632  IWRLLVTEEGTLAEKVTTDANANLEKAYHHMVKTVTNHYENLRFNTGISQLMIFINEAYK  691
            + RL+ T E      +T + ++ L+K Y++ VK+VT++ ++++FNT+I+QLM+F+N A K
Sbjct  664  VYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANK  717

Query  692  QDTIPKQYVEGFVQLLSPIAPHLAEELWEIL-GHTETISYVAWPTYDETKLVEDEVEIVL  750
            +D +  +Y  GFVQL++P+APHL+EELW+ L +  E+ISYV+WP+YDE+KLVE++VEIV+
Sbjct  718  EDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVV  777

Query  751  QVNGKVKSKITVAKSLGKEELEKIAQEDNKMKENLEGKTIRKVIVVPGKLVNIVAN  806
            Q++GKVK+K+ VAK L++EEL+ +A  ++K++ ++ GK I KVI VP KLVNIV +
Sbjct  778  QIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

166) M640_07285 in NC_021839


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  945 bits (3581),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 564/836 (68%), Positives = 693/836 (83%), Gaps = 41/836 (4%)

Query  6    FNHKKMEPKWQQYWSEHNTFKTTEDKNKDNFYALDMFPYPSGAGLHVGHPEGYTATDILS  65
            ++H  +EPKWQ +W++++TFKT  D +K +FYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  66   RMKRMQGKNVLHPIGWDAFGLPAEQYAIDTGNDPEEFTALNIANFTRQIKSLGFSYDWDR  125
            R KR QG NVLHP+GWDAFGLPAEQYA+DTGNDP EFTA NIANF RQI++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  126  EINTTDPEYYKWTQWIFEKLYEKGLAYEAEIAVNWCPALGTVLANEEVI-DGKSERGGFP  184
            E+NTTDP+YYKWTQWIF KLYEKGLAYEAE++VNW   LGT +ANEEV+ DG SERGG+P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  185  VFRKPMRQWMLKITAYAdrllddldlvdWPENIKDMQRNWIGRSEGAEVTFKIKDSDETF  244
            V RKPMRQWMLKITAYA+RLL+DL+ VDWPE+IKDMQRNWIG+S GA+VTFK+KD+D  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  245  NVFTTRPDTLFGATYTVFAPEHELIEKITTPEQKEAVEAYKKQVELKSELERTDLAKDKT  304
             VFTTRPDTLFGATY+V+APEH L++ ITT++Q EAV  YK+Q  LKS+L RTDLAK+KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  305  GVFTGAYAINPINGEEVPIWIADYVLIQYGTGAIMAVPAHDERDFEFAQQFGLNIRPVLE  364
            GV TG+YAINP+NG E+P+WIADYVL  YGTGAIMAVPAHDERD EFA+QF L+I PVLE
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  365  GGDVTKEAFTGDGPHINSDFLNGLAKAEAITAAIDWLEKEGIGSRKITYRLRDWLFSRQR  424
            GG+V   AFT DG HINSDFL+GL KA AI+  ++WLE EG+G+ ++TYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  425  YWGEPIPVIHWEDGettlvpedelplllpKATEIKPSGTGESPLANLHDWVNVTDKNGRK  484
            YWGEPIP+IHWEDG +T VPE ELPL+LP + +I+PSGTGESPLAN+ DW++VT  +G K
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  485  GRRETNTMPQWAGSSWYFLRYIDPNNSEAIADKEKLAEWLPVDVYIGGAEHAVLHLLYAR  544
            GRRETNTMPQWAGSSWY+LRYIDP+N+E +AD E L +WLPVD+Y+GGAEHAVLHLLYAR
Sbjct  484  GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYAR  543

Query  545  FWHKFLYDIGVVPTKEPFQKLFNQGMILG-------------------------------  573
            FWHK LYD+GVVPTKEPFQKLFNQGMILG                               
Sbjct  544  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEE  603

Query  574  --ENNEKMSKSRGNVVNPDEVVEKYGADTLRLYEMFMGPLEASIAWNENGLEGARKFLDR  631
              +   KMSKS  NVVNPD+VVE+YGADTLR+YEMFMGPL+ASIAW+E+GLEG+RKFLDR
Sbjct  604  LEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR  663

Query  632  IWRLLVTEEGTLAEKVTTDANANLEKAYHHMVKTVTNHYENLRFNTGISQLMIFINEAYK  691
            + RL+ T E      +T + ++ L+K Y++ VK+VT++ ++++FNT+I+QLM+F+N A K
Sbjct  664  VYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANK  717

Query  692  QDTIPKQYVEGFVQLLSPIAPHLAEELWEIL-GHTETISYVAWPTYDETKLVEDEVEIVL  750
            +D +  +Y  GFVQL++P+APHL+EELW+ L +  E+ISYV+WP+YDE+KLVE++VEIV+
Sbjct  718  EDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVV  777

Query  751  QVNGKVKSKITVAKSLEKEELEKIAQEDNKMKENLEGKTIRKVIVVPGKLVNIVAN  806
            Q++GKVK+K+ VAK L +EEL+ +A  ++K++ ++ GK I KVI VP KLVNIV +
Sbjct  778  QIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

167) M644_07640 in NC_021827


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  945 bits (3581),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 564/836 (68%), Positives = 693/836 (83%), Gaps = 41/836 (4%)

Query  6    FNHKKMEPKWQQYWSEHNTFKTTEDKNKDNFYALDMFPYPSGAGLHVGHPEGYTATDILS  65
            ++H  +EPKWQ +W++++TFKT  D +K +FYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  66   RMKRMQGKNVLHPIGWDAFGLPAEQYAIDTGNDPEEFTALNIANFTRQIKSLGFSYDWDR  125
            R KR QG NVLHP+GWDAFGLPAEQYA+DTGNDP EFTA NIANF RQI++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  126  EINTTDPEYYKWTQWIFEKLYEKGLAYEAEIAVNWCPALGTVLANEEVI-DGKSERGGFP  184
            E+NTTDP+YYKWTQWIF KLYEKGLAYEAE++VNW   LGT +ANEEV+ DG SERGG+P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  185  VFRKPMRQWMLKITAYAdrllddldlvdWPENIKDMQRNWIGRSEGAEVTFKIKDSDETF  244
            V RKPMRQWMLKITAYA+RLL+DL+ VDWPE+IKDMQRNWIG+S GA+VTFK+KD+D  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  245  NVFTTRPDTLFGATYTVFAPEHELIEKITTPEQKEAVEAYKKQVELKSELERTDLAKDKT  304
             VFTTRPDTLFGATY+V+APEH L++ ITT++Q EAV  YK+Q  LKS+L RTDLAK+KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  305  GVFTGAYAINPINGEEVPIWIADYVLIQYGTGAIMAVPAHDERDFEFAQQFGLNIRPVLE  364
            GV TG+YAINP+NG E+P+WIADYVL  YGTGAIMAVPAHDERD EFA+QF L+I PVLE
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  365  GGDVTKEAFTGDGPHINSDFLNGLAKAEAITAAIDWLEKEGIGSRKITYRLRDWLFSRQR  424
            GG+V   AFT DG HINSDFL+GL KA AI+  ++WLE EG+G+ ++TYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  425  YWGEPIPVIHWEDGettlvpedelplllpKATEIKPSGTGESPLANLHDWVNVTDKNGRK  484
            YWGEPIP+IHWEDG +T VPE ELPL+LP + +I+PSGTGESPLAN+ DW++VT  +G K
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  485  GRRETNTMPQWAGSSWYFLRYIDPNNSEAIADKEKLAEWLPVDVYIGGAEHAVLHLLYAR  544
            GRRETNTMPQWAGSSWY+LRYIDP+N+E +AD E L +WLPVD+Y+GGAEHAVLHLLYAR
Sbjct  484  GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYAR  543

Query  545  FWHKFLYDIGVVPTKEPFQKLFNQGMILG-------------------------------  573
            FWHK LYD+GVVPTKEPFQKLFNQGMILG                               
Sbjct  544  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEE  603

Query  574  --ENNEKMSKSRGNVVNPDEVVEKYGADTLRLYEMFMGPLEASIAWNENGLEGARKFLDR  631
              +   KMSKS  NVVNPD+VVE+YGADTLR+YEMFMGPL+ASIAW+E+GLEG+RKFLDR
Sbjct  604  LEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR  663

Query  632  IWRLLVTEEGTLAEKVTTDANANLEKAYHHMVKTVTNHYENLRFNTGISQLMIFINEAYK  691
            + RL+ T E      +T + ++ L+K Y++ VK+VT++ ++++FNT+I+QLM+F+N A K
Sbjct  664  VYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANK  717

Query  692  QDTIPKQYVEGFVQLLSPIAPHLAEELWEIL-GHTETISYVAWPTYDETKLVEDEVEIVL  750
            +D +  +Y  GFVQL++P+APHL+EELW+ L +  E+ISYV+WP+YDE+KLVE++VEIV+
Sbjct  718  EDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVV  777

Query  751  QVNGKVKSKITVAKSLEKEELEKIAQEDNKMKENLEGKTIRKVIVVPGKLVNIVAN  806
            Q++GKVK+K+ VAK L +EEL+ +A  ++K++ ++ GK I KVI VP KLVNIV +
Sbjct  778  QIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

168) M645_07820 in NC_021840


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  945 bits (3581),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 564/836 (68%), Positives = 693/836 (83%), Gaps = 41/836 (4%)

Query  6    FNHKKMEPKWQQYWSEHNTFKTTEDKNKDNFYALDMFPYPSGAGLHVGHPEGYTATDILS  65
            ++H  +EPKWQ +W++++TFKT  D +K +FYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  66   RMKRMQGKNVLHPIGWDAFGLPAEQYAIDTGNDPEEFTALNIANFTRQIKSLGFSYDWDR  125
            R KR QG NVLHP+GWDAFGLPAEQYA+DTGNDP EFTA NIANF RQI++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  126  EINTTDPEYYKWTQWIFEKLYEKGLAYEAEIAVNWCPALGTVLANEEVI-DGKSERGGFP  184
            E+NTTDP+YYKWTQWIF KLYEKGLAYEAE++VNW   LGT +ANEEV+ DG SERGG+P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  185  VFRKPMRQWMLKITAYAdrllddldlvdWPENIKDMQRNWIGRSEGAEVTFKIKDSDETF  244
            V RKPMRQWMLKITAYA+RLL+DL+ VDWPE+IKDMQRNWIG+S GA+VTFK+KD+D  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  245  NVFTTRPDTLFGATYTVFAPEHELIEKITTPEQKEAVEAYKKQVELKSELERTDLAKDKT  304
             VFTTRPDTLFGATY+V+APEH L++ ITT++Q EAV  YK+Q  LKS+L RTDLAK+KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  305  GVFTGAYAINPINGEEVPIWIADYVLIQYGTGAIMAVPAHDERDFEFAQQFGLNIRPVLE  364
            GV TG+YAINP+NG E+P+WIADYVL  YGTGAIMAVPAHDERD EFA+QF L+I PVLE
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  365  GGDVTKEAFTGDGPHINSDFLNGLAKAEAITAAIDWLEKEGIGSRKITYRLRDWLFSRQR  424
            GG+V   AFT DG HINSDFL+GL KA AI+  ++WLE EG+G+ ++TYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  425  YWGEPIPVIHWEDGettlvpedelplllpKATEIKPSGTGESPLANLHDWVNVTDKNGRK  484
            YWGEPIP+IHWEDG +T VPE ELPL+LP + +I+PSGTGESPLAN+ DW++VT  +G K
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  485  GRRETNTMPQWAGSSWYFLRYIDPNNSEAIADKEKLAEWLPVDVYIGGAEHAVLHLLYAR  544
            GRRETNTMPQWAGSSWY+LRYIDP+N+E +AD E L +WLPVD+Y+GGAEHAVLHLLYAR
Sbjct  484  GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYAR  543

Query  545  FWHKFLYDIGVVPTKEPFQKLFNQGMILG-------------------------------  573
            FWHK LYD+GVVPTKEPFQKLFNQGMILG                               
Sbjct  544  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEE  603

Query  574  --ENNEKMSKSRGNVVNPDEVVEKYGADTLRLYEMFMGPLEASIAWNENGLEGARKFLDR  631
              +   KMSKS  NVVNPD+VVE+YGADTLR+YEMFMGPL+ASIAW+E+GLEG+RKFLDR
Sbjct  604  LEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR  663

Query  632  IWRLLVTEEGTLAEKVTTDANANLEKAYHHMVKTVTNHYENLRFNTGISQLMIFINEAYK  691
            + RL+ T E      +T + ++ L+K Y++ VK+VT++ ++++FNT+I+QLM+F+N A K
Sbjct  664  VYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANK  717

Query  692  QDTIPKQYVEGFVQLLSPIAPHLAEELWEIL-GHTETISYVAWPTYDETKLVEDEVEIVL  750
            +D +  +Y  GFVQL++P+APHL+EELW+ L +  E+ISYV+WP+YDE+KLVE++VEIV+
Sbjct  718  EDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVV  777

Query  751  QVNGKVKSKITVAKSLEKEELEKIAQEDNKMKENLEGKTIRKVIVVPGKLVNIVAN  806
            Q++GKVK+K+ VAK L +EEL+ +A  ++K++ ++ GK I KVI VP KLVNIV +
Sbjct  778  QIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

169) M637_11300 in NC_021824


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  945 bits (3579),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 564/836 (68%), Positives = 692/836 (83%), Gaps = 41/836 (4%)

Query  6    FNHKKMEPKWQQYWSEHNTFKTTEDKNKDNFYALDMFPYPSGAGLHVGHPEGYTATDILS  65
            ++H  +EPKWQ +W++++TFKT  D +K +FYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  66   RMKRMQGKNVLHPIGWDAFGLPAEQYAIDTGNDPEEFTALNIANFTRQIKSLGFSYDWDR  125
            R KR QG NVLHP+GWDAFGLPAEQYA+DTGNDP EFTA NIANF RQI++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  126  EINTTDPEYYKWTQWIFEKLYEKGLAYEAEIAVNWCPALGTVLANEEVI-DGKSERGGFP  184
            E+NTTDP+YYKWTQWIF KLYEKGLAYEAE++VNW   LGT +ANEEV+ DG SERGG+P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  185  VFRKPMRQWMLKITAYAdrllddldlvdWPENIKDMQRNWIGRSEGAEVTFKIKDSDETF  244
            V RKPMRQWMLKITAYA+RLL+DL+ VDWPE+IKDMQRNWIG+S GA+VTFK+KD+D  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  245  NVFTTRPDTLFGATYTVFAPEHELIEKITTPEQKEAVEAYKKQVELKSELERTDLAKDKT  304
             VFTTRPDTLFGATY+V+APEH L++ ITT++Q EAV  YK+Q  LKS+L RTDLAK+KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  305  GVFTGAYAINPINGEEVPIWIADYVLIQYGTGAIMAVPAHDERDFEFAQQFGLNIRPVLE  364
            GV TG+YAINP+NG E+P+WIADYVL  YGTGAIMAVPAHDERD EFA+QF L+I PVLE
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  365  GGDVTKEAFTGDGPHINSDFLNGLAKAEAITAAIDWLEKEGIGSRKITYRLRDWLFSRQR  424
            GG+V   AFT DG HINSDFL+GL KA AI+  ++WLE EG+G+ ++TYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  425  YWGEPIPVIHWEDGettlvpedelplllpKATEIKPSGTGESPLANLHDWVNVTDKNGRK  484
            YWGEPIP+IHWEDG +T VPE ELPL+LP + +I+PSGTGESPLAN+ DW++VT  +G K
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  485  GRRETNTMPQWAGSSWYFLRYIDPKNSEAIADKEKLAEWLPVDVYIGGAEHAVLHLLYAR  544
            GRRETNTMPQWAGSSWY+LRYIDP N+E +AD E L +WLPVD+Y+GGAEHAVLHLLYAR
Sbjct  484  GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYAR  543

Query  545  FWHKFLYDIGVVPTKEPFQKLFNQGMILG-------------------------------  573
            FWHK LYD+GVVPTKEPFQKLFNQGMILG                               
Sbjct  544  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEE  603

Query  574  --ENNEKMSKSRGNVVNPDEVVEKYGADTLRLYEMFMGPLEASIAWNENGLEGARKFLDR  631
              +   KMSKS  NVVNPD+VVE+YGADTLR+YEMFMGPL+ASIAW+E+GLEG+RKFLDR
Sbjct  604  LEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR  663

Query  632  IWRLLVTEEGTLAEKVTTDANANLEKAYHHMVKTVTNHYENLRFNTGISQLMIFINEAYK  691
            + RL+ T E      +T + ++ L+K Y++ VK+VT++ ++++FNT+I+QLM+F+N A K
Sbjct  664  VYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANK  717

Query  692  QDTIPKQYVEGFVQLLSPIAPHLAEELWEIL-GHTETISYVAWPTYDETKLVEDEVEIVL  750
            +D +  +Y  GFVQL++P+APHL+EELW+ L +  E+ISYV+WP+YDE+KLVE++VEIV+
Sbjct  718  EDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVV  777

Query  751  QVNGKVKSKITVAKSLEKEELEKIAQEDNKMKENLEGKTIRKVIVVPGKLVNIVAN  806
            Q++GKVK+K+ VAK L +EEL+ +A  ++K++ ++ GK I KVI VP KLVNIV +
Sbjct  778  QIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

170) M638_11030 in NC_021825


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  945 bits (3581),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 564/836 (68%), Positives = 693/836 (83%), Gaps = 41/836 (4%)

Query  6    FNHKKMEPKWQQYWSEHNTFKTTEDKNKDNFYALDMFPYPSGAGLHVGHPEGYTATDILS  65
            ++H  +EPKWQ +W++++TFKT  D +K +FYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  66   RMKRMQGKNVLHPIGWDAFGLPAEQYAIDTGNDPEEFTALNIANFTRQIKSLGFSYDWDR  125
            R KR QG NVLHP+GWDAFGLPAEQYA+DTGNDP EFTA NIANF RQI++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  126  EINTTDPEYYKWTQWIFEKLYEKGLAYEAEIAVNWCPALGTVLANEEVI-DGKSERGGFP  184
            E+NTTDP+YYKWTQWIF KLYEKGLAYEAE++VNW   LGT +ANEEV+ DG SERGG+P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  185  VFRKPMRQWMLKITAYAdrllddldlvdWPENIKDMQRNWIGRSEGAEVTFKIKDSDETF  244
            V RKPMRQWMLKITAYA+RLL+DL+ VDWPE+IKDMQRNWIG+S GA+VTFK+KD+D  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  245  NVFTTRPDTLFGATYTVFAPEHELIEKITTPEQKEAVEAYKKQVELKSELERTDLAKDKT  304
             VFTTRPDTLFGATY+V+APEH L++ ITT++Q EAV  YK+Q  LKS+L RTDLAK+KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  305  GVFTGAYAINPINGEEVPIWIADYVLIQYGTGAIMAVPAHDERDFEFAQQFGLNIRPVLE  364
            GV TG+YAINP+NG E+P+WIADYVL  YGTGAIMAVPAHDERD EFA+QF L+I PVLE
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  365  GGDVTKEAFTGDGPHINSDFLNGLAKAEAITAAIDWLEKEGIGSRKITYRLRDWLFSRQR  424
            GG+V   AFT DG HINSDFL+GL KA AI+  ++WLE EG+G+ ++TYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  425  YWGEPIPVIHWEDGettlvpedelplllpKATEIKPSGTGESPLANLHDWVNVTDKNGRK  484
            YWGEPIP+IHWEDG +T VPE ELPL+LP + +I+PSGTGESPLAN+ DW++VT  +G K
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  485  GRRETNTMPQWAGSSWYFLRYIDPNNSEAIADKEKLAEWLPVDVYIGGAEHAVLHLLYAR  544
            GRRETNTMPQWAGSSWY+LRYIDP+N+E +AD E L +WLPVD+Y+GGAEHAVLHLLYAR
Sbjct  484  GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYAR  543

Query  545  FWHKFLYDIGVVPTKEPFQKLFNQGMILG-------------------------------  573
            FWHK LYD+GVVPTKEPFQKLFNQGMILG                               
Sbjct  544  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEE  603

Query  574  --ENNEKMSKSRGNVVNPDEVVEKYGADTLRLYEMFMGPLEASIAWNENGLEGARKFLDR  631
              +   KMSKS  NVVNPD+VVE+YGADTLR+YEMFMGPL+ASIAW+E+GLEG+RKFLDR
Sbjct  604  LEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR  663

Query  632  IWRLLVTEEGTLAEKVTTDANANLEKAYHHMVKTVTNHYENLRFNTGISQLMIFINEAYK  691
            + RL+ T E      +T + ++ L+K Y++ VK+VT++ ++++FNT+I+QLM+F+N A K
Sbjct  664  VYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANK  717

Query  692  QDTIPKQYVEGFVQLLSPIAPHLAEELWEIL-GHTETISYVAWPTYDETKLVEDEVEIVL  750
            +D +  +Y  GFVQL++P+APHL+EELW+ L +  E+ISYV+WP+YDE+KLVE++VEIV+
Sbjct  718  EDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVV  777

Query  751  QVNGKVKSKITVAKSLEKEELEKIAQEDNKMKENLEGKTIRKVIVVPGKLVNIVAN  806
            Q++GKVK+K+ VAK L +EEL+ +A  ++K++ ++ GK I KVI VP KLVNIV +
Sbjct  778  QIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

171) M643_03220 in NC_021826


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  945 bits (3581),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 564/836 (68%), Positives = 693/836 (83%), Gaps = 41/836 (4%)

Query  6    FNHKKMEPKWQQYWSEHNTFKTTEDKNKDNFYALDMFPYPSGAGLHVGHPEGYTATDILS  65
            ++H  +EPKWQ +W++++TFKT  D +K +FYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  66   RMKRMQGKNVLHPIGWDAFGLPAEQYAIDTGNDPEEFTALNIANFTRQIKSLGFSYDWDR  125
            R KR QG NVLHP+GWDAFGLPAEQYA+DTGNDP EFTA NIANF RQI++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  126  EINTTDPEYYKWTQWIFEKLYEKGLAYEAEIAVNWCPALGTVLANEEVI-DGKSERGGFP  184
            E+NTTDP+YYKWTQWIF KLYEKGLAYEAE++VNW   LGT +ANEEV+ DG SERGG+P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  185  VFRKPMRQWMLKITAYAdrllddldlvdWPENIKDMQRNWIGRSEGAEVTFKIKDSDETF  244
            V RKPMRQWMLKITAYA+RLL+DL+ VDWPE+IKDMQRNWIG+S GA+VTFK+KD+D  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  245  NVFTTRPDTLFGATYTVFAPEHELIEKITTPEQKEAVEAYKKQVELKSELERTDLAKDKT  304
             VFTTRPDTLFGATY+V+APEH L++ ITT++Q EAV  YK+Q  LKS+L RTDLAK+KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  305  GVFTGAYAINPINGEEVPIWIADYVLIQYGTGAIMAVPAHDERDFEFAQQFGLNIRPVLE  364
            GV TG+YAINP+NG E+P+WIADYVL  YGTGAIMAVPAHDERD EFA+QF L+I PVLE
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  365  GGDVTKEAFTGDGPHINSDFLNGLAKAEAITAAIDWLEKEGIGSRKITYRLRDWLFSRQR  424
            GG+V   AFT DG HINSDFL+GL KA AI+  ++WLE EG+G+ ++TYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  425  YWGEPIPVIHWEDGettlvpedelplllpKATEIKPSGTGESPLANLHDWVNVTDKNGRK  484
            YWGEPIP+IHWEDG +T VPE ELPL+LP + +I+PSGTGESPLAN+ DW++VT  +G K
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  485  GRRETNTMPQWAGSSWYFLRYIDPNNSEAIADKEKLAEWLPVDVYIGGAEHAVLHLLYAR  544
            GRRETNTMPQWAGSSWY+LRYIDP+N+E +AD E L +WLPVD+Y+GGAEHAVLHLLYAR
Sbjct  484  GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYAR  543

Query  545  FWHKFLYDIGVVPTKEPFQKLFNQGMILG-------------------------------  573
            FWHK LYD+GVVPTKEPFQKLFNQGMILG                               
Sbjct  544  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEE  603

Query  574  --ENNEKMSKSRGNVVNPDEVVEKYGADTLRLYEMFMGPLEASIAWNENGLEGARKFLDR  631
              +   KMSKS  NVVNPD+VVE+YGADTLR+YEMFMGPL+ASIAW+E+GLEG+RKFLDR
Sbjct  604  LEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR  663

Query  632  IWRLLVTEEGTLAEKVTTDANANLEKAYHHMVKTVTNHYENLRFNTGISQLMIFINEAYK  691
            + RL+ T E      +T + ++ L+K Y++ VK+VT++ ++++FNT+I+QLM+F+N A K
Sbjct  664  VYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANK  717

Query  692  QDTIPKQYVEGFVQLLSPIAPHLAEELWEIL-GHTETISYVAWPTYDETKLVEDEVEIVL  750
            +D +  +Y  GFVQL++P+APHL+EELW+ L +  E+ISYV+WP+YDE+KLVE++VEIV+
Sbjct  718  EDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVV  777

Query  751  QVNGKVKSKITVAKSLEKEELEKIAQEDNKMKENLEGKTIRKVIVVPGKLVNIVAN  806
            Q++GKVK+K+ VAK L +EEL+ +A  ++K++ ++ GK I KVI VP KLVNIV +
Sbjct  778  QIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

172) M641_05150 in NC_021838


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  945 bits (3581),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 564/836 (68%), Positives = 693/836 (83%), Gaps = 41/836 (4%)

Query  6    FNHKKMEPKWQQYWSEHNTFKTTEDKNKDNFYALDMFPYPSGAGLHVGHPEGYTATDILS  65
            ++H  +EPKWQ +W++++TFKT  D +K +FYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  66   RMKRMQGKNVLHPIGWDAFGLPAEQYAIDTGNDPEEFTALNIANFTRQIKSLGFSYDWDR  125
            R KR QG NVLHP+GWDAFGLPAEQYA+DTGNDP EFTA NIANF RQI++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  126  EINTTDPEYYKWTQWIFEKLYEKGLAYEAEIAVNWCPALGTVLANEEVI-DGKSERGGFP  184
            E+NTTDP+YYKWTQWIF KLYEKGLAYEAE++VNW   LGT +ANEEV+ DG SERGG+P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  185  VFRKPMRQWMLKITAYAdrllddldlvdWPENIKDMQRNWIGRSEGAEVTFKIKDSDETF  244
            V RKPMRQWMLKITAYA+RLL+DL+ VDWPE+IKDMQRNWIG+S GA+VTFK+KD+D  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  245  NVFTTRPDTLFGATYTVFAPEHELIEKITTPEQKEAVEAYKKQVELKSELERTDLAKDKT  304
             VFTTRPDTLFGATY+V+APEH L++ ITT++Q EAV  YK+Q  LKS+L RTDLAK+KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  305  GVFTGAYAINPINGEEVPIWIADYVLIQYGTGAIMAVPAHDERDFEFAQQFGLNIRPVLE  364
            GV TG+YAINP+NG E+P+WIADYVL  YGTGAIMAVPAHDERD EFA+QF L+I PVLE
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  365  GGDVTKEAFTGDGPHINSDFLNGLAKAEAITAAIDWLEKEGIGSRKITYRLRDWLFSRQR  424
            GG+V   AFT DG HINSDFL+GL KA AI+  ++WLE EG+G+ ++TYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  425  YWGEPIPVIHWEDGettlvpedelplllpKATEIKPSGTGESPLANLHDWVNVTDKNGRK  484
            YWGEPIP+IHWEDG +T VPE ELPL+LP + +I+PSGTGESPLAN+ DW++VT  +G K
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  485  GRRETNTMPQWAGSSWYFLRYIDPNNSEAIADKEKLAEWLPVDVYIGGAEHAVLHLLYAR  544
            GRRETNTMPQWAGSSWY+LRYIDP+N+E +AD E L +WLPVD+Y+GGAEHAVLHLLYAR
Sbjct  484  GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYAR  543

Query  545  FWHKFLYDIGVVPTKEPFQKLFNQGMILG-------------------------------  573
            FWHK LYD+GVVPTKEPFQKLFNQGMILG                               
Sbjct  544  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEE  603

Query  574  --ENNEKMSKSRGNVVNPDEVVEKYGADTLRLYEMFMGPLEASIAWNENGLEGARKFLDR  631
              +   KMSKS  NVVNPD+VVE+YGADTLR+YEMFMGPL+ASIAW+E+GLEG+RKFLDR
Sbjct  604  LEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR  663

Query  632  IWRLLVTEEGTLAEKVTTDANANLEKAYHHMVKTVTNHYENLRFNTGISQLMIFINEAYK  691
            + RL+ T E      +T + ++ L+K Y++ VK+VT++ ++++FNT+I+QLM+F+N A K
Sbjct  664  VYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANK  717

Query  692  QDTIPKQYVEGFVQLLSPIAPHLAEELWEIL-GHTETISYVAWPTYDETKLVEDEVEIVL  750
            +D +  +Y  GFVQL++P+APHL+EELW+ L +  E+ISYV+WP+YDE+KLVE++VEIV+
Sbjct  718  EDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVV  777

Query  751  QVNGKVKSKITVAKSLEKEELEKIAQEDNKMKENLEGKTIRKVIVVPGKLVNIVAN  806
            Q++GKVK+K+ VAK L +EEL+ +A  ++K++ ++ GK I KVI VP KLVNIV +
Sbjct  778  QIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

173) leuS in NC_013768


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  944 bits (3577),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 564/836 (68%), Positives = 694/836 (84%), Gaps = 41/836 (4%)

Query  6    FNHKKMEPKWQQYWSEHNTFKTTEDNNKENFYALDMFPYPSGAGLHVGHPEGYTATDILS  65
            ++H  +EPKWQ +W++++TFKT  D +K +FYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  66   RMKRMQGKNVLHPIGWDAFGLPAEQYAIDTGNDPEEFTALNIANFTRQIKSLGFSYDWDR  125
            R KR QG NVLHP+GWDAFGLPAEQYA+DTGNDP EFTA NIANF RQI++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  126  EINTTDPEYYKWTQWIFEKLYENGLAYEAEIAVNWCPALGTVLANEEVI-DGKSERGGFP  184
            E+NTTDP+YYKWTQWIF KLYE+GLAYEAE++VNW   LGT +ANEEV+ DG SERGG+P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  185  VFRKPMRQWMLKITAYAdrllddldlvdWPENIKDMQRNWIGRSEGAEVTFKIKDSDETF  244
            V RKPMRQWMLKITAYA+RLL+DL+ VDWPE+IKDMQRNWIG+S GA+VTFK+KD+D  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  245  NVFTTRPDTLFGATYTVFAPEHELIEKITTPEQKEAVESYKKQVELKSELERTDLAKDKT  304
             VFTTRPDTLFGATY+V+APEH L++ ITT++Q EAV  YK+Q  LKS+L RTDLAK+KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  305  GVFTGAYAINPINGEEVPIWIADYVLIQYGTGAIMAVPAHDERDFEFAQQFGLNIRPVLE  364
            GV TG+YAINP+NG E+P+WIADYVL  YGTGAIMAVPAHDERD EFA+QF L+I PVLE
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  365  GGDVTKEAFTGDGPHINSDFLNGLAKAEAITAAIDWLEKEGIGSRKITYRLRDWLFSRQR  424
            GG+V   AFT DG HINSDFL+GL KA AI+  ++WLE EG+G+ ++TYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  425  YWGEPIPVIHWEDGettlvpeeelplllpkateIKPSGTGESPLANLHDWVNVTDENGRK  484
            YWGEPIP+IHWEDG +T VPE ELPL+LP + +I+PSGTGESPLAN+ DW++VT E+G K
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  485  GRRETNTMPQWAGSSWYFLRYIDPKNSEAIADKEKLAEWLPVDVYIGGAEHAVLHLLYAR  544
            GRRETNTMPQWAGSSWY+LRYIDP N+E +AD E L +WLPVD+Y+GGAEHAVLHLLYAR
Sbjct  484  GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYAR  543

Query  545  FWHKFLYDIGVVPTKEPFQKLFNQGMILG-------------------------------  573
            FWHK LYD+GVVPTKEPFQKLFNQGMILG                               
Sbjct  544  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEE  603

Query  574  --ENNEKMSKSRGNVVNPDEVVEKYGADTLRLYEMFMGPLEASIAWNENGLEGARKFLDR  631
              +   KMSKS  NVVNPD+VVE+YGADTLR+YEMFMGPL+ASIAW+E+GLEG+RKFLDR
Sbjct  604  LEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR  663

Query  632  IWRLLVTEEGTLAEKVTTDANANLEKAYHHMVKTVTNHYENLRFNTGISQLMIFINEAYK  691
            + RL+ T E      +T + ++ L+K Y++ VK+VT++ ++++FNT+I+QLM+F+N A K
Sbjct  664  VYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANK  717

Query  692  QDTIPKQYVEGFVQLLSPIAPHLAEELWEIL-GHTETISYVAWPTYDEAKLVEDEVEIVL  750
            +D +  +Y  GFVQL++P+APHL+EELW+ L +  E+ISYV+WP+YDE+KLVE++VEIV+
Sbjct  718  EDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVV  777

Query  751  QVNGKVKSKITVAKSLGKEELEKIAQEDNKMKENLEGKTIRKVIVVPGKLVNIVAN  806
            Q++GKVK+K+ VAK L++EEL+ +A  ++K++ ++ GK I KVI VP KLVNIV +
Sbjct  778  QIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

174) leuS in NC_003210


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  944 bits (3575),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 564/836 (68%), Positives = 694/836 (84%), Gaps = 41/836 (4%)

Query  3    FNHKKMEPKWQQYWSEHNTFKTTEDKNKENFYALDMFPYPSGAGLHVGHPEGYTATDILS  62
            ++H  +EPKWQ +W++++TFKT  D +K +FYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMKRMQGKNVLHPIGWDAFGLPAEQYAIDTGNDPEEFTALNIANFTRQIKSLGFSYDWDR  122
            R KR QG NVLHP+GWDAFGLPAEQYA+DTGNDP EFTA NIANF RQI++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EINTTDPEYYKWTQWIFEKLYENGLAYEAEIAVNWCPALGTVLANEEVI-DGKSERGGFP  181
            E+NTTDP+YYKWTQWIF KLYE+GLAYEAE++VNW   LGT +ANEEV+ DG SERGG+P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VFRKPMRQWMLKITAYAdrllddldlvdWPENIKDMQRNWIGRSEGAEVTFKIKDSDETF  241
            V RKPMRQWMLKITAYA+RLL+DL+ VDWPE+IKDMQRNWIG+S GA+VTFK+KD+D  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  NVFTTRPDTLFGATYTVFAPEHELIEKITTPEQKEAVEAYKKQVELKSELERTDLAKDKT  301
             VFTTRPDTLFGATY+V+APEH L++ ITT++Q EAV  YK+Q  LKS+L RTDLAK+KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAINPINGEEVPIWIADYVLIQYGTGAIMAVPAHDERDFEFAQQFGLNIRPVLE  361
            GV TG+YAINP+NG E+P+WIADYVL  YGTGAIMAVPAHDERD EFA+QF L+I PVLE
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGDVTKEAFTGDGPHINSDFLNGLAKAEAITAAIDWLEKEGIGSRKITYRLRDWLFSRQR  421
            GG+V   AFT DG HINSDFL+GL KA AI+  ++WLE EG+G+ ++TYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPVIHWEDGettlvpeeelplllpkateIKPSGTGESPLANLHDWVNVTDENGRK  481
            YWGEPIP+IHWEDG +T VPE ELPL+LP + +I+PSGTGESPLAN+ DW++VT E+G K
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  482  GRRETNTMPQWAGSSWYFLRYIDPKNSEAIADKEKLAEWLPVDVYIGGAEHAVLHLLYAR  541
            GRRETNTMPQWAGSSWY+LRYIDP N+E +AD E L +WLPVD+Y+GGAEHAVLHLLYAR
Sbjct  484  GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYAR  543

Query  542  FWHKFLYDIGVVPTKEPFQKLFNQGMILG-------------------------------  570
            FWHK LYD+GVVPTKEPFQKLFNQGMILG                               
Sbjct  544  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEE  603

Query  571  --ENNEKMSKSRGNVVNPDEVVEKYGADTLRLYEMFMGPLEASIAWNENGLEGARKFLDR  628
              +   KMSKS  NVVNPD+VVE+YGADTLR+YEMFMGPL+ASIAW+E+GLEG+RKFLDR
Sbjct  604  LEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR  663

Query  629  IWRLLVTEEGTLAEKVTTDANANLEKAYHHMVKTVTNHYENLRFNTGISQLMIFINEAYK  688
            + RL+ T E      +T + ++ L+K Y++ VK+VT++ ++++FNT+I+QLM+F+N A K
Sbjct  664  VYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANK  717

Query  689  QDTIPKQYVEGFVQLLSPIAPHLAEELWEIL-GHTETISYVAWPTYDETKLVEDEVEIVL  747
            +D +  +Y  GFVQL++P+APHL+EELW+ L +  E+ISYV+WP+YDE+KLVE++VEIV+
Sbjct  718  EDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVV  777

Query  748  QVNGKVKSKITVAKSLGKEELEKIAQEDNKMKENLEGKTIRKVIVVPGKLVNIVAN  803
            Q++GKVK+K+ VAK L++EEL+ +A  ++K++ ++ GK I KVI VP KLVNIV +
Sbjct  778  QIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

175) LMKG_02977 in NC_017546


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  944 bits (3575),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 564/836 (68%), Positives = 694/836 (84%), Gaps = 41/836 (4%)

Query  3    FNHKKMEPKWQQYWSEHNTFKTTEDKNKENFYALDMFPYPSGAGLHVGHPEGYTATDILS  62
            ++H  +EPKWQ +W++++TFKT  D +K +FYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMKRMQGKNVLHPIGWDAFGLPAEQYAIDTGNDPEEFTALNIANFTRQIKSLGFSYDWDR  122
            R KR QG NVLHP+GWDAFGLPAEQYA+DTGNDP EFTA NIANF RQI++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EINTTDPEYYKWTQWIFEKLYENGLAYEAEIAVNWCPALGTVLANEEVI-DGKSERGGFP  181
            E+NTTDP+YYKWTQWIF KLYE+GLAYEAE++VNW   LGT +ANEEV+ DG SERGG+P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VFRKPMRQWMLKITAYAdrllddldlvdWPENIKDMQRNWIGRSEGAEVTFKIKDSDETF  241
            V RKPMRQWMLKITAYA+RLL+DL+ VDWPE+IKDMQRNWIG+S GA+VTFK+KD+D  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  NVFTTRPDTLFGATYTVFAPEHELIEKITTPEQKEAVEAYKKQVELKSELERTDLAKDKT  301
             VFTTRPDTLFGATY+V+APEH L++ ITT++Q EAV  YK+Q  LKS+L RTDLAK+KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAINPINGEEVPIWIADYVLIQYGTGAIMAVPAHDERDFEFAQQFGLNIRPVLE  361
            GV TG+YAINP+NG E+P+WIADYVL  YGTGAIMAVPAHDERD EFA+QF L+I PVLE
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGDVTKEAFTGDGPHINSDFLNGLAKAEAITAAIDWLEKEGIGSRKITYRLRDWLFSRQR  421
            GG+V   AFT DG HINSDFL+GL KA AI+  ++WLE EG+G+ ++TYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPVIHWEDGettlvpeeelplllpkateIKPSGTGESPLANLHDWVNVTDENGRK  481
            YWGEPIP+IHWEDG +T VPE ELPL+LP + +I+PSGTGESPLAN+ DW++VT E+G K
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  482  GRRETNTMPQWAGSSWYFLRYIDPKNSEAIADKEKLAEWLPVDVYIGGAEHAVLHLLYAR  541
            GRRETNTMPQWAGSSWY+LRYIDP N+E +AD E L +WLPVD+Y+GGAEHAVLHLLYAR
Sbjct  484  GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYAR  543

Query  542  FWHKFLYDIGVVPTKEPFQKLFNQGMILG-------------------------------  570
            FWHK LYD+GVVPTKEPFQKLFNQGMILG                               
Sbjct  544  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEE  603

Query  571  --ENNEKMSKSRGNVVNPDEVVEKYGADTLRLYEMFMGPLEASIAWNENGLEGARKFLDR  628
              +   KMSKS  NVVNPD+VVE+YGADTLR+YEMFMGPL+ASIAW+E+GLEG+RKFLDR
Sbjct  604  LEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR  663

Query  629  IWRLLVTEEGTLAEKVTTDANANLEKAYHHMVKTVTNHYENLRFNTGISQLMIFINEAYK  688
            + RL+ T E      +T + ++ L+K Y++ VK+VT++ ++++FNT+I+QLM+F+N A K
Sbjct  664  VYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANK  717

Query  689  QDTIPKQYVEGFVQLLSPIAPHLAEELWEIL-GHTETISYVAWPTYDETKLVEDEVEIVL  747
            +D +  +Y  GFVQL++P+APHL+EELW+ L +  E+ISYV+WP+YDE+KLVE++VEIV+
Sbjct  718  EDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVV  777

Query  748  QVNGKVKSKITVAKSLGKEELEKIAQEDNKMKENLEGKTIRKVIVVPGKLVNIVAN  803
            Q++GKVK+K+ VAK L++EEL+ +A  ++K++ ++ GK I KVI VP KLVNIV +
Sbjct  778  QIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

176) LMOG_00027 in NC_017545


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  944 bits (3575),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 564/836 (68%), Positives = 694/836 (84%), Gaps = 41/836 (4%)

Query  3    FNHKKMEPKWQQYWSEHNTFKTTEDKNKENFYALDMFPYPSGAGLHVGHPEGYTATDILS  62
            ++H  +EPKWQ +W++++TFKT  D +K +FYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMKRMQGKNVLHPIGWDAFGLPAEQYAIDTGNDPEEFTALNIANFTRQIKSLGFSYDWDR  122
            R KR QG NVLHP+GWDAFGLPAEQYA+DTGNDP EFTA NIANF RQI++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EINTTDPEYYKWTQWIFEKLYENGLAYEAEIAVNWCPALGTVLANEEVI-DGKSERGGFP  181
            E+NTTDP+YYKWTQWIF KLYE+GLAYEAE++VNW   LGT +ANEEV+ DG SERGG+P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VFRKPMRQWMLKITAYAdrllddldlvdWPENIKDMQRNWIGRSEGAEVTFKIKDSDETF  241
            V RKPMRQWMLKITAYA+RLL+DL+ VDWPE+IKDMQRNWIG+S GA+VTFK+KD+D  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  NVFTTRPDTLFGATYTVFAPEHELIEKITTPEQKEAVEAYKKQVELKSELERTDLAKDKT  301
             VFTTRPDTLFGATY+V+APEH L++ ITT++Q EAV  YK+Q  LKS+L RTDLAK+KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAINPINGEEVPIWIADYVLIQYGTGAIMAVPAHDERDFEFAQQFGLNIRPVLE  361
            GV TG+YAINP+NG E+P+WIADYVL  YGTGAIMAVPAHDERD EFA+QF L+I PVLE
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGDVTKEAFTGDGPHINSDFLNGLAKAEAITAAIDWLEKEGIGSRKITYRLRDWLFSRQR  421
            GG+V   AFT DG HINSDFL+GL KA AI+  ++WLE EG+G+ ++TYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPVIHWEDGettlvpeeelplllpkateIKPSGTGESPLANLHDWVNVTDENGRK  481
            YWGEPIP+IHWEDG +T VPE ELPL+LP + +I+PSGTGESPLAN+ DW++VT E+G K
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  482  GRRETNTMPQWAGSSWYFLRYIDPKNSEAIADKEKLAEWLPVDVYIGGAEHAVLHLLYAR  541
            GRRETNTMPQWAGSSWY+LRYIDP N+E +AD E L +WLPVD+Y+GGAEHAVLHLLYAR
Sbjct  484  GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYAR  543

Query  542  FWHKFLYDIGVVPTKEPFQKLFNQGMILG-------------------------------  570
            FWHK LYD+GVVPTKEPFQKLFNQGMILG                               
Sbjct  544  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEE  603

Query  571  --ENNEKMSKSRGNVVNPDEVVEKYGADTLRLYEMFMGPLEASIAWNENGLEGARKFLDR  628
              +   KMSKS  NVVNPD+VVE+YGADTLR+YEMFMGPL+ASIAW+E+GLEG+RKFLDR
Sbjct  604  LEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR  663

Query  629  IWRLLVTEEGTLAEKVTTDANANLEKAYHHMVKTVTNHYENLRFNTGISQLMIFINEAYK  688
            + RL+ T E      +T + ++ L+K Y++ VK+VT++ ++++FNT+I+QLM+F+N A K
Sbjct  664  VYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANK  717

Query  689  QDTIPKQYVEGFVQLLSPIAPHLAEELWEIL-GHTETISYVAWPTYDETKLVEDEVEIVL  747
            +D +  +Y  GFVQL++P+APHL+EELW+ L +  E+ISYV+WP+YDE+KLVE++VEIV+
Sbjct  718  EDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVV  777

Query  748  QVNGKVKSKITVAKSLGKEELEKIAQEDNKMKENLEGKTIRKVIVVPGKLVNIVAN  803
            Q++GKVK+K+ VAK L++EEL+ +A  ++K++ ++ GK I KVI VP KLVNIV +
Sbjct  778  QIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

177) leuS in NC_013766


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  944 bits (3577),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 564/836 (68%), Positives = 694/836 (84%), Gaps = 41/836 (4%)

Query  6    FNHKKMEPKWQQYWSEHNTFKTTEDNNKENFYALDMFPYPSGAGLHVGHPEGYTATDILS  65
            ++H  +EPKWQ +W++++TFKT  D +K +FYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  66   RMKRMQGKNVLHPIGWDAFGLPAEQYAIDTGNDPEEFTALNIANFTRQIKSLGFSYDWDR  125
            R KR QG NVLHP+GWDAFGLPAEQYA+DTGNDP EFTA NIANF RQI++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  126  EINTTDPEYYKWTQWIFEKLYENGLAYEAEIAVNWCPALGTVLANEEVI-DGKSERGGFP  184
            E+NTTDP+YYKWTQWIF KLYE+GLAYEAE++VNW   LGT +ANEEV+ DG SERGG+P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  185  VFRKPMRQWMLKITAYAdrllddldlvdWPENIKDMQRNWIGRSEGAEVTFKIKDSDETF  244
            V RKPMRQWMLKITAYA+RLL+DL+ VDWPE+IKDMQRNWIG+S GA+VTFK+KD+D  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  245  NVFTTRPDTLFGATYTVFAPEHELIEKITTPEQKEAVESYKKQVELKSELERTDLAKDKT  304
             VFTTRPDTLFGATY+V+APEH L++ ITT++Q EAV  YK+Q  LKS+L RTDLAK+KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  305  GVFTGAYAINPINGEEVPIWIADYVLIQYGTGAIMAVPAHDERDFEFAQQFGLNIRPVLE  364
            GV TG+YAINP+NG E+P+WIADYVL  YGTGAIMAVPAHDERD EFA+QF L+I PVLE
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  365  GGDVTKEAFTGDGPHINSDFLNGLAKAEAITAAIDWLEKEGIGSRKITYRLRDWLFSRQR  424
            GG+V   AFT DG HINSDFL+GL KA AI+  ++WLE EG+G+ ++TYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  425  YWGEPIPVIHWEDGettlvpeeelplllpkateIKPSGTGESPLANLHDWVNVTDENGRK  484
            YWGEPIP+IHWEDG +T VPE ELPL+LP + +I+PSGTGESPLAN+ DW++VT E+G K
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  485  GRRETNTMPQWAGSSWYFLRYIDPKNSEAIADKEKLAEWLPVDVYIGGAEHAVLHLLYAR  544
            GRRETNTMPQWAGSSWY+LRYIDP N+E +AD E L +WLPVD+Y+GGAEHAVLHLLYAR
Sbjct  484  GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYAR  543

Query  545  FWHKFLYDIGVVPTKEPFQKLFNQGMILG-------------------------------  573
            FWHK LYD+GVVPTKEPFQKLFNQGMILG                               
Sbjct  544  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEE  603

Query  574  --ENNEKMSKSRGNVVNPDEVVEKYGADTLRLYEMFMGPLEASIAWNENGLEGARKFLDR  631
              +   KMSKS  NVVNPD+VVE+YGADTLR+YEMFMGPL+ASIAW+E+GLEG+RKFLDR
Sbjct  604  LEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR  663

Query  632  IWRLLVTEEGTLAEKVTTDANANLEKAYHHMVKTVTNHYENLRFNTGISQLMIFINEAYK  691
            + RL+ T E      +T + ++ L+K Y++ VK+VT++ ++++FNT+I+QLM+F+N A K
Sbjct  664  VYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANK  717

Query  692  QDTIPKQYVEGFVQLLSPIAPHLAEELWEIL-GHTETISYVAWPTYDEAKLVEDEVEIVL  750
            +D +  +Y  GFVQL++P+APHL+EELW+ L +  E+ISYV+WP+YDE+KLVE++VEIV+
Sbjct  718  EDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVV  777

Query  751  QVNGKVKSKITVAKSLGKEELEKIAQEDNKMKENLEGKTIRKVIVVPGKLVNIVAN  806
            Q++GKVK+K+ VAK L++EEL+ +A  ++K++ ++ GK I KVI VP KLVNIV +
Sbjct  778  QIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

178) leuS in NC_018704


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  943 bits (3573),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 575/837 (69%), Positives = 679/837 (82%), Gaps = 44/837 (5%)

Query  3    YDHKKIETKWNKYWLENKTFKTNIRSEKKKFYALDMFPYPSGAGLHVGHPEGYTATDILS  62
            YDH  IE KW+ +W +N TFKT   + K KFYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMKRMQGYEVLHPMGWDAFGLPAEQYALDTGNDPAEFTDKNIDTFRRQIQDLGFSYDWDR  122
            R KR QG +VLHPMGWDAFGLPAEQYA+DTGNDPAEFT  NI  F+RQI+ LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EINTTDPNYYKWTQWIFLKLYEKGLAYIDEVPVNWCPALGTVLANEEVI-DGLSERGGHP  181
            E+NTTDPNYYKWTQWIF KLYEKGLAY  EVPVNW   LGT +ANEEV+ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRPMKQWMLRITAYAdrlledldeldWPESIKEMQRNWIGRSEGANVTFEVAGQDKTF  241
            V R+PM+QWML+ITAYA+RLLEDL+E+DWPESIK+MQRNWIG+S GANVTF V + DK F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  TVFTTRPDTLFGATYAVLAPEHSLVSQITTPEQKEAVEQYIEKIKSKSDLERTDLAKEKT  301
            TVFTTRPDTLFGATYAVLAPEH+LV  ITT++Q EAV +Y  +   KSDL RTDLAKEKT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAINPINNKQIPIWIADYVLASYGTGAIMSVPAHDQRDYEFAKTFDLEIIPVLE  361
            GV TG+YAINP+N K++P+WIADYVLASYGTGAIM+VPAHD+RD EFAK F+L+IIPVLE
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGNIEVEAFTGDGKHINSDFLNGLNKEEAINKAIEWLESEGKGERKVTYRLRDWLFSRQR  421
            GGN+E  AFT DG HINSDFL+GL+K  AI K +EWLE+EG G+ +VTYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPIIHWEDGTVTGVDESELPVMLPKTTEIKPSGTGESPLANIEEWVNVTDPKTGM  481
            YWGEPIPIIHWEDGT T+V ESELP++LP T +I+PSGTGESPLAN+ +W++VT    G+
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT-REDGV  482

Query  482  KGRRETNTMPQWAGSSWYYLRYIDPNNTEKIADEDLLKEWLPVDIYIGGAEHAVLHLLYA  541
            KGRRETNTMPQWAGSSWYYLRYIDP+NTEK+ADE+LLK+WLPVDIY+GGAEHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKFLYDIGVVSTKEPFQKLFNQGMILG------------------------------  571
            RFWHK LYD+GVV+TKEPFQKLFNQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---ENNEKMSKSKGNVVNPDDIVESHGADTLRLYEMFMGPLDASIAWSEAGLDGSRRFLD  628
               +   KMSKS  NVVNPDD+VE  GADTLR+YEMFMGPLDASIAWSE GL+GSR+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RVWRLFVDEETDKLSPKIVNQVEQDQLEKVYHETVKQVTDNFTSLKFNTAISQMMVFINE  688
            RV RL        ++ K + + + + L+KVY+ETVK VT++   +KFNTAI+Q+MVF+N 
Sbjct  663  RVYRL--------ITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNA  714

Query  689  AYKAEQILKDYVEGFVKLLSPVAPFIAEELWSKL-GYSETIAYEPWPEYDGAKLEENEVE  747
            A K ++++ DY  GFV+L++P AP ++EELW  L + +E+I+Y PWP YD +KL EN+VE
Sbjct  715  ANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVE  774

Query  748  IVIQILGKNRARIMVDKDATKEELEKLALDNEIIKEKIAGKTVRKVIVVPGKLVNIV  804
            IV+QI GK +A+++V KD ++EEL+ +AL NE ++  IAGK + KVI VP KLVNIV
Sbjct  775  IVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIV  831

179) LMLG_1184 in NC_017547


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  943 bits (3574),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 564/836 (68%), Positives = 694/836 (84%), Gaps = 41/836 (4%)

Query  41   FNHKKMEPKWQQYWSEHNTFKTTEDKNKENFYALDMFPYPSGAGLHVGHPEGYTATDILS  100
            ++H  +EPKWQ +W++++TFKT  D +K +FYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  101  RMKRMQGKNVLHPIGWDAFGLPAEQYAIDTGNDPEEFTALNIANFTRQIKSLGFSYDWDR  160
            R KR QG NVLHP+GWDAFGLPAEQYA+DTGNDP EFTA NIANF RQI++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  161  EINTTDPEYYKWTQWIFEKLYENGLAYEAEIAVNWCPALGTVLANEEVI-DGKSERGGFP  219
            E+NTTDP+YYKWTQWIF KLYE+GLAYEAE++VNW   LGT +ANEEV+ DG SERGG+P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  220  VFRKPMRQWMLKITAYAdrllddldlvdWPENIKDMQRNWIGRSEGAEVTFKIKDSDETF  279
            V RKPMRQWMLKITAYA+RLL+DL+ VDWPE+IKDMQRNWIG+S GA+VTFK+KD+D  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  280  NVFTTRPDTLFGATYTVFAPEHELIEKITTPEQKEAVEAYKKQVELKSELERTDLAKDKT  339
             VFTTRPDTLFGATY+V+APEH L++ ITT++Q EAV  YK+Q  LKS+L RTDLAK+KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  340  GVFTGAYAINPINGEEVPIWIADYVLIQYGTGAIMAVPAHDERDFEFAQQFGLNIRPVLE  399
            GV TG+YAINP+NG E+P+WIADYVL  YGTGAIMAVPAHDERD EFA+QF L+I PVLE
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  400  GGDVTKEAFTGDGPHINSDFLNGLAKAEAITAAIDWLEKEGIGSRKITYRLRDWLFSRQR  459
            GG+V   AFT DG HINSDFL+GL KA AI+  ++WLE EG+G+ ++TYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  460  YWGEPIPVIHWEDGettlvpedelplllpKATEIKPSGTGESPLANLHDWVNVTDENGRK  519
            YWGEPIP+IHWEDG +T VPE ELPL+LP + +I+PSGTGESPLAN+ DW++VT E+G K
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  520  GRRETNTMPQWAGSSWYFLRYIDPKNSEAIADKEKLAEWLPVDVYIGGAEHAVLHLLYAR  579
            GRRETNTMPQWAGSSWY+LRYIDP N+E +AD E L +WLPVD+Y+GGAEHAVLHLLYAR
Sbjct  484  GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYAR  543

Query  580  FWHKFLYDIGVVPTKEPFQKLFNQGMILG-------------------------------  608
            FWHK LYD+GVVPTKEPFQKLFNQGMILG                               
Sbjct  544  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEE  603

Query  609  --ENNEKMSKSRGNVVNPDEVVEKYGADTLRLYEMFMGPLEASIAWNENGLEGARKFLDR  666
              +   KMSKS  NVVNPD+VVE+YGADTLR+YEMFMGPL+ASIAW+E+GLEG+RKFLDR
Sbjct  604  LEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR  663

Query  667  IWRLLVTEEGTLAEKVTTDANANLEKAYHHMVKTVTNHYENLRFNTGISQLMIFINEAYK  726
            + RL+ T E      +T + ++ L+K Y++ VK+VT++ ++++FNT+I+QLM+F+N A K
Sbjct  664  VYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANK  717

Query  727  QDTIPKQYVEGFVQLLSPIAPHLAEELWEIL-GHTETISYVAWPTYDETKLVEDEVEIVL  785
            +D +  +Y  GFVQL++P+APHL+EELW+ L +  E+ISYV+WP+YDE+KLVE++VEIV+
Sbjct  718  EDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVV  777

Query  786  QVNGKVKSKITVAKSLGKEELEKIAQEDNKMKENLEGKTIRKVIVVPGKLVNIVAN  841
            Q++GKVK+K+ VAK L++EEL+ +A  ++K++ ++ GK I KVI VP KLVNIV +
Sbjct  778  QIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

180) leuS in NC_018588


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  943 bits (3574),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 564/836 (68%), Positives = 694/836 (84%), Gaps = 41/836 (4%)

Query  6    FNHKKMEPKWQQYWSEHNTFKTTEDKNKENFYALDMFPYPSGAGLHVGHPEGYTATDILS  65
            ++H  +EPKWQ +W++++TFKT  D +K +FYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  66   RMKRMQGKNVLHPIGWDAFGLPAEQYAIDTGNDPEEFTALNIANFTRQIKSLGFSYDWDR  125
            R KR QG NVLHP+GWDAFGLPAEQYA+DTGNDP EFTA NIANF RQI++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  126  EINTTDPEYYKWTQWIFEKLYENGLAYEAEIAVNWCPALGTVLANEEVI-DGKSERGGFP  184
            E+NTTDP+YYKWTQWIF KLYE+GLAYEAE++VNW   LGT +ANEEV+ DG SERGG+P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  185  VFRKPMRQWMLKITAYAdrllddldlvdWPENIKDMQRNWIGRSEGAEVTFKIKDSDETF  244
            V RKPMRQWMLKITAYA+RLL+DL+ VDWPE+IKDMQRNWIG+S GA+VTFK+KD+D  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  245  NVFTTRPDTLFGATYTVFAPEHELIEKITTPEQKEAVEAYKKQVELKSELERTDLAKDKT  304
             VFTTRPDTLFGATY+V+APEH L++ ITT++Q EAV  YK+Q  LKS+L RTDLAK+KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  305  GVFTGAYAINPINGEEVPIWIADYVLIQYGTGAIMAVPAHDERDFEFAQQFGLNIRPVLE  364
            GV TG+YAINP+NG E+P+WIADYVL  YGTGAIMAVPAHDERD EFA+QF L+I PVLE
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  365  GGDVTKEAFTGDGPHINSDFLNGLAKAEAITAAIDWLEKEGIGSRKITYRLRDWLFSRQR  424
            GG+V   AFT DG HINSDFL+GL KA AI+  ++WLE EG+G+ ++TYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  425  YWGEPIPVIHWEDGettlvpeeelplllpkateIKPSGTGESPLANLHDWVNVTDENGRK  484
            YWGEPIP+IHWEDG +T VPE ELPL+LP + +I+PSGTGESPLAN+ DW++VT E+G K
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  485  GRRETNTMPQWAGSSWYFLRYIDPKNSEAIADKEKLAEWLPVDVYIGGAEHAVLHLLYAR  544
            GRRETNTMPQWAGSSWY+LRYIDP N+E +AD E L +WLPVD+Y+GGAEHAVLHLLYAR
Sbjct  484  GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYAR  543

Query  545  FWHKFLYDIGVVPTKEPFQKLFNQGMILG-------------------------------  573
            FWHK LYD+GVVPTKEPFQKLFNQGMILG                               
Sbjct  544  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEE  603

Query  574  --ENNEKMSKSRGNVVNPDEVVEKYGADTLRLYEMFMGPLEASIAWNENGLEGARKFLDR  631
              +   KMSKS  NVVNPD+VVE+YGADTLR+YEMFMGPL+ASIAW+E+GLEG+RKFLDR
Sbjct  604  LEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR  663

Query  632  IWRLLVTEEGTLAEKVTTDANANLEKAYHHMVKTVTNHYENLRFNTGISQLMIFINEAYK  691
            + RL+ T E      +T + ++ L+K Y++ VK+VT++ ++++FNT+I+QLM+F+N A K
Sbjct  664  VYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANK  717

Query  692  QDTIPKQYVEGFVQLLSPIAPHLAEELWEIL-GHTETISYVAWPTYDETKLVEDEVEIVL  750
            +D +  +Y  GFVQL++P+APHL+EELW+ L +  E+ISYV+WP+YDE+KLVE++VEIV+
Sbjct  718  EDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVV  777

Query  751  QVNGKVKSKITVAKSLGKEELEKIAQEDNKMKENLEGKTIRKVIVVPGKLVNIVAN  806
            Q++GKVK+K+ VAK L++EEL+ +A  ++K++ ++ GK I KVI VP KLVNIV +
Sbjct  778  QIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

181) leuS in NC_018589


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  943 bits (3574),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 564/836 (68%), Positives = 694/836 (84%), Gaps = 41/836 (4%)

Query  6    FNHKKMEPKWQQYWSEHNTFKTTEDKNKENFYALDMFPYPSGAGLHVGHPEGYTATDILS  65
            ++H  +EPKWQ +W++++TFKT  D +K +FYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  66   RMKRMQGKNVLHPIGWDAFGLPAEQYAIDTGNDPEEFTALNIANFTRQIKSLGFSYDWDR  125
            R KR QG NVLHP+GWDAFGLPAEQYA+DTGNDP EFTA NIANF RQI++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  126  EINTTDPEYYKWTQWIFEKLYENGLAYEAEIAVNWCPALGTVLANEEVI-DGKSERGGFP  184
            E+NTTDP+YYKWTQWIF KLYE+GLAYEAE++VNW   LGT +ANEEV+ DG SERGG+P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  185  VFRKPMRQWMLKITAYAdrllddldlvdWPENIKDMQRNWIGRSEGAEVTFKIKDSDETF  244
            V RKPMRQWMLKITAYA+RLL+DL+ VDWPE+IKDMQRNWIG+S GA+VTFK+KD+D  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  245  NVFTTRPDTLFGATYTVFAPEHELIEKITTPEQKEAVEAYKKQVELKSELERTDLAKDKT  304
             VFTTRPDTLFGATY+V+APEH L++ ITT++Q EAV  YK+Q  LKS+L RTDLAK+KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  305  GVFTGAYAINPINGEEVPIWIADYVLIQYGTGAIMAVPAHDERDFEFAQQFGLNIRPVLE  364
            GV TG+YAINP+NG E+P+WIADYVL  YGTGAIMAVPAHDERD EFA+QF L+I PVLE
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  365  GGDVTKEAFTGDGPHINSDFLNGLAKAEAITAAIDWLEKEGIGSRKITYRLRDWLFSRQR  424
            GG+V   AFT DG HINSDFL+GL KA AI+  ++WLE EG+G+ ++TYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  425  YWGEPIPVIHWEDGettlvpeeelplllpkateIKPSGTGESPLANLHDWVNVTDENGRK  484
            YWGEPIP+IHWEDG +T VPE ELPL+LP + +I+PSGTGESPLAN+ DW++VT E+G K
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  485  GRRETNTMPQWAGSSWYFLRYIDPKNSEAIADKEKLAEWLPVDVYIGGAEHAVLHLLYAR  544
            GRRETNTMPQWAGSSWY+LRYIDP N+E +AD E L +WLPVD+Y+GGAEHAVLHLLYAR
Sbjct  484  GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYAR  543

Query  545  FWHKFLYDIGVVPTKEPFQKLFNQGMILG-------------------------------  573
            FWHK LYD+GVVPTKEPFQKLFNQGMILG                               
Sbjct  544  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEE  603

Query  574  --ENNEKMSKSRGNVVNPDEVVEKYGADTLRLYEMFMGPLEASIAWNENGLEGARKFLDR  631
              +   KMSKS  NVVNPD+VVE+YGADTLR+YEMFMGPL+ASIAW+E+GLEG+RKFLDR
Sbjct  604  LEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR  663

Query  632  IWRLLVTEEGTLAEKVTTDANANLEKAYHHMVKTVTNHYENLRFNTGISQLMIFINEAYK  691
            + RL+ T E      +T + ++ L+K Y++ VK+VT++ ++++FNT+I+QLM+F+N A K
Sbjct  664  VYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANK  717

Query  692  QDTIPKQYVEGFVQLLSPIAPHLAEELWEIL-GHTETISYVAWPTYDETKLVEDEVEIVL  750
            +D +  +Y  GFVQL++P+APHL+EELW+ L +  E+ISYV+WP+YDE+KLVE++VEIV+
Sbjct  718  EDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVV  777

Query  751  QVNGKVKSKITVAKSLGKEELEKIAQEDNKMKENLEGKTIRKVIVVPGKLVNIVAN  806
            Q++GKVK+K+ VAK L++EEL+ +A  ++K++ ++ GK I KVI VP KLVNIV +
Sbjct  778  QIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

182) M639_09005 in NC_021837


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  943 bits (3573),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 564/836 (68%), Positives = 694/836 (84%), Gaps = 41/836 (4%)

Query  6    FNHKKMEPKWQQYWSEHNTFKTTEDKNKENFYALDMFPYPSGAGLHVGHPEGYTATDILS  65
            ++H  +EPKWQ +W++++TFKT  D +K +FYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  66   RMKRMQGKNVLHPIGWDAFGLPAEQYAIDTGNDPEEFTALNIANFTRQIKSLGFSYDWDR  125
            R KR QG NVLHP+GWDAFGLPAEQYA+DTGNDP EFTA NIANF RQI++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  126  EINTTDPEYYKWTQWIFEKLYENGLAYEAEIAVNWCPALGTVLANEEVI-DGKSERGGFP  184
            E+NTTDP+YYKWTQWIF KLYE+GLAYEAE++VNW   LGT +ANEEV+ DG SERGG+P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  185  VFRKPMRQWMLKITAYAdrllddldlvdWPENIKDMQRNWIGRSEGAEVTFKIKDSDETF  244
            V RKPMRQWMLKITAYA+RLL+DL+ VDWPE+IKDMQRNWIG+S GA+VTFK+KD+D  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  245  NVFTTRPDTLFGATYTVFAPEHELIEKITTPEQKEAVESYKKQVELKSELERTDLAKDKT  304
             VFTTRPDTLFGATY+V+APEH L++ ITT++Q EAV  YK+Q  LKS+L RTDLAK+KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  305  GVFTGAYAINPINGEEVPIWIADYVLIQYGTGAIMAVPAHDERDFEFAQQFGLNIRPVLE  364
            GV TG+YAINP+NG E+P+WIADYVL  YGTGAIMAVPAHDERD EFA+QF L+I PVLE
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  365  GGDVTKEAFTGDGPHINSDFLNGLAKAEAITAAIDWLEKEGIGSRKITYRLRDWLFSRQR  424
            GG+V   AFT DG HINSDFL+GL KA AI+  ++WLE EG+G+ ++TYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  425  YWGEPIPVIHWEDGettlvpeeelplllpkateIKPSGTGESPLANLHDWVNVTDENGRK  484
            YWGEPIP+IHWEDG +T VPE ELPL+LP + +I+PSGTGESPLAN+ DW++VT E+G K
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  485  GRRETNTMPQWAGSSWYFLRYIDPKNSEAIADKEKLAEWLPVDVYIGGAEHAVLHLLYAR  544
            GRRETNTMPQWAGSSWY+LRYIDP N+E +AD E L +WLPVD+Y+GGAEHAVLHLLYAR
Sbjct  484  GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYAR  543

Query  545  FWHKFLYDIGVVPTKEPFQKLFNQGMILG-------------------------------  573
            FWHK LYD+GVVPTKEPFQKLFNQGMILG                               
Sbjct  544  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEE  603

Query  574  --ENNEKMSKSRGNVVNPDEVVEKYGADTLRLYEMFMGPLEASIAWNENGLEGARKFLDR  631
              +   KMSKS  NVVNPD+VVE+YGADTLR+YEMFMGPL+ASIAW+E+GLEG+RKFLDR
Sbjct  604  LEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR  663

Query  632  IWRLLVTEEGTLAEKVTTDANANLEKAYHHMVKTVTNHYENLRFNTGISQLMIFINEAYK  691
            + RL+ T E      +T + ++ L+K Y++ VK+VT++ ++++FNT+I+QLM+F+N A K
Sbjct  664  VYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANK  717

Query  692  QDTIPKQYVEGFVQLLSPIAPHLAEELWEIL-GHTETISYVAWPTYDETKLVEDEVEIVL  750
            +D +  +Y  GFVQL++P+APHL+EELW+ L +  E+ISYV+WP+YDE+KLVE++VEIV+
Sbjct  718  EDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVV  777

Query  751  QVNGKVKSKITVAKSLGKEELEKIAQEDNKMKENLEGKTIRKVIVVPGKLVNIVAN  806
            Q++GKVK+K+ VAK L++EEL+ +A  ++K++ ++ GK I KVI VP KLVNIV +
Sbjct  778  QIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

183) leuS in NC_007576


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  943 bits (3573),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 558/840 (67%), Positives = 671/840 (80%), Gaps = 45/840 (5%)

Query  3    YDHRAVEQKWQAYWQSHKSFKTTEDKDKKNFYALDMFPYPSGQGLHVGHPEGYTATDILA  62
            YDH A+E KWQA+W  + +FKT  D  K +FYALDMFPYPSG GLHVGHPEGYTATDIL+
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMKRMQGFNVLHPMGWDAFGLPAEQYALDTGNNPADFTQKNINTFKRQINSLGFSYDWDR  122
            R KR QG NVLHPMGWDAFGLPAEQYA+DTGN+PA+FT  NI  FKRQIN+LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVNTTDPDFYKWTQWIFEKMYEKGLAYEAEVAVNWSPDLGTVVANEEVI-DGKTERGGYP  181
            EVNTTDP++YKWTQWIF K+YEKGLAYEAEV+VNW  +LGT +ANEEV+ DG +ERGGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VYRKPMRQWMLKITAYADRLIDDLDLVDWPESVKDMQRNWIGRSKGAEVSFAVENHDANI  241
            V RKPMRQWMLKITAYA+RL++DL+ VDWPES+KDMQRNWIG+S GA+V+F V + D ++
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  DVFTTRADTMFGVSYIVMAPEHKLVADITTPEQKAAVDAYLKEIEHKSDLERTDLAKDKT  301
             VFTTR+DT+FG +Y V+APEH LV  ITT++Q  AV  Y ++   KSDL RTDLAK+KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GAFTGAYAINPVNGERLPIWISDYVLASYGTGAVMAVPAHDPRDWEFAKKFGLPLKPVVS  361
            G  TG+YAINPVNG  +P+WI+DYVLASYGTGA+MAVPAHD RDWEFAK+F L + PV+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGNPEEAVHTEPGVMINSDFLDGLDKQAAIDKMIPWLVEHKVGHEQISYKLRDWLFSRQR  421
            GGN EEA  TE G+ INSDFLDGLDK +AI KM+ WL  + VG+E+++Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPIIHWEDGTTSVVPEDQLPLELPLTSDIKPSGTGESPLANLTDWLNVTDENGRK  481
            YWGEPIPIIHWEDGT++ VPE +LPL LP+T DI+PSGTGESPLAN+TDWL+VT E+G K
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  482  GRRETNTMPQWAGSSWYYLRYIDPKNPDKLADFDKLKDWLPVDMYIGGAEHAVLHLLYVR  541
            GRRETNTMPQWAGSSWYYLRYIDP N +KLAD + LK+WLPVD+Y+GGAEHAVLHLLY R
Sbjct  484  GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYAR  543

Query  542  FWHKFLYDIGVVPTKEPFQHLYNQGMILG-------------------------------  570
            FWHK LYD+GVVPTKEPFQ L+NQGMILG                               
Sbjct  544  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEE  603

Query  571  --DNHEKMSKSKGNVVNPDDVVDRFGADTLRLYEMFMGPLDASISWSEKGLAGARKFLDR  628
              +   KMSKS  NVVNPDDVV+++GADTLR+YEMFMGPLDASI+WSE GL G+RKFLDR
Sbjct  604  LEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR  663

Query  629  VWRLYTEEDTDENDQLSSKIVADNNDQLKKVYNETVKKVTEDFESMHFNVAISQLMVFIN  688
            V RL T  +          I  +N++ L KVYNETVK VTE+ + M FN AI+QLMVF+N
Sbjct  664  VYRLITTKE----------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVN  713

Query  689  DAYKADTFPREYAEGFVKLLAPIAPHMMEELWAML-GHDDSISYVDWPTFDPAALIANEV  747
             A K D +  +YA GFV+L+AP+APH+ EELW  L + ++SISYV WP++D + L+ N+V
Sbjct  714  AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDV  773

Query  748  EVIFQVNGKLKAKVTVAKDTPKEELEAMAKANEKVAEFIADKTVRKVIAIPNKLVNIVAN  807
            E++ Q++GK+KAK+ VAKD ++EEL+ +A ANEKV   IA+K + KVIA+PNKLVNIV +
Sbjct  774  EIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

184) leuS in NC_008555


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  940 bits (3560),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 565/834 (68%), Positives = 688/834 (83%), Gaps = 41/834 (4%)

Query  3    FNHKKMEPKWQQYWSEHNTFKTTEDKDKENFYALDMFPYPSGAGLHVGHPEGYTATDILS  62
            ++H  +EPKWQ +W++++TFKT  D  K +FYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMKRMQGKNVLHPIGWDAFGLPAEQYAIDTGNDPEEFTALNIANFTRQIKSLGFSYDWDR  122
            R KR QG NVLHP+GWDAFGLPAEQYA+DTGNDP EFTA NIANF RQI++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EINTTDPEYYKWTQWIFEKLYENGLAYEAEIAVNWCPALGTVLANEEVI-DGKSERGGFP  181
            E+NTTDP+YYKWTQWIF KLYE+GLAYEAE++VNW   LGT +ANEEV+ DG SERGG+P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VFRKPMRQWMLKITAYAdrllddldlvdWPENIKDMQRNWIGRSEGAEVTFKIKDSDETF  241
            V RKPMRQWMLKITAYA+RLL+DL+ VDWPE+IKDMQRNWIG+S GA+VTFK+KD+D  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  NVFTTRPDTLFGATYTVFAPEHELIEKITTPEQKEAVETYKKQVELKSELERTDLAKDKT  301
             VFTTRPDTLFGATY+V+APEH L++ ITT++Q EAV  YK+Q  LKS+L RTDLAK+KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAINPINGEEVPIWIADYVLIQYGTGAIMAVPAHDERDFEFAQQFGLNIRPVLE  361
            GV TG+YAINP+NG E+P+WIADYVL  YGTGAIMAVPAHDERD EFA+QF L+I PVLE
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGDVTKEAFTGDGPHINSEFLDGLAKEEAITAAIDWLEKEGIGSRKITYRLRDWLFSRQR  421
            GG+V   AFT DG HINS+FLDGL K  AI+  ++WLE EG+G+ ++TYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPVIHWEDGettlvpeeelplllpkateIKPSGTGESPLANLHDWVNVTDESGRK  481
            YWGEPIP+IHWEDG +T VPE ELPL+LP + +I+PSGTGESPLAN+ DW++VT E G K
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  482  GRRETNTMPQWAGSSWYFLRYIDPKNTEAIADKEKLIEWLPVDVYIGGAEHAVLHLLYAR  541
            GRRETNTMPQWAGSSWY+LRYIDP NTE +AD E L +WLPVD+Y+GGAEHAVLHLLYAR
Sbjct  484  GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYAR  543

Query  542  FWHKFLYDIGVVPTKEPFQKLFNQGMILG-------------------------------  570
            FWHK LYD+GVVPTKEPFQKLFNQGMILG                               
Sbjct  544  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEE  603

Query  571  --ENNEKMSKSRGNVVNPDEVVEKYGADTLRMYEMFMGPLDASIAWNENGLEGARKFLDR  628
              +   KMSKS  NVVNPD+VVE+YGADTLR+YEMFMGPLDASIAW+E+GLEG+RKFLDR
Sbjct  604  LEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR  663

Query  629  IWRLFVTEEGILAEKVTTTANANLEKAYHHMVKTVTNHYENLRFNTGISQLMIFINEAYK  688
            + RL+ T E      +T   ++ L+K Y++ VK+VT++ ++++FNT+I+QLM+F+N A K
Sbjct  664  VYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANK  717

Query  689  QDSIPKEYVEGFVQLLSPIAPHLAEELWEIL-GHTETISYVTWPTYDETKLVEDEVEIVL  747
            +D +  +Y  GFVQL++P+APHL+EELW+ L +  E+ISYV WP+YDE+KLVE++VEIV+
Sbjct  718  EDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVV  777

Query  748  QVNGKVKSKITVAKSLGKEELEKIAQEDDKMKENLEGKTIRKVIVVPGKLVNIV  801
            Q++GKVK+K+ VAK L++EEL+ +A  ++K++ ++ GK I KVI VP KLVNIV
Sbjct  778  QIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIV  831

185) leuS in NC_004193


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  940 bits (3563),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 547/837 (66%), Positives = 672/837 (81%), Gaps = 42/837 (5%)

Query  3    FQHRQIEKKWQDYWEDNKTFKTDTFSNKEKFYALDMFPYPSGQGLHVGHPEGYTATDILA  62
            ++H  IE KWQ +W DN TFKT+T ++K KFYALDMFPYPSG GLHVGHPEGYTATDIL+
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMKRMQGYEVMHPMGWDAFGLPAEQYAIDTGNSPAEFTNQNINTFKRQIKELGFSYDWDR  122
            R KR QG +V+HPMGWDAFGLPAEQYA+DTGN PAEFT +NI  FKRQI+ LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EINTTDPNYYKWTQWIFKKLYENDLAYMDEVAVNWCPALGTVLANEEVI-DGKSERGGHP  181
            E+NTTDPNYYKWTQWIF KLYE++LAY  EV+VNW   LGT +ANEEV+ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VIRKPMKQWMLKITAYADRLLEDLNELDWPDSLKEMQRNWIGRSEGAEVTFSIKGNEGTF  241
            V+RKPM+QWMLKITAYA+RLLEDL+E+DWP+S+K+MQRNWIG+S GA+VTF +K+ +  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  TVFTTRPDTLFGATYAVVAPEHPLVKEITTLSQKEAVQNYLDEIQTKSDLERTDLAKDKT  301
            TVFTTRPDTLFGATYAV+APEH+LV  ITT  Q EAV +Y  +   KSDL RTDLAK+KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAINPVNGEEMPIWVADYVLMSYGTGAIMAVPAHDERDYEFANTFGLPIKEVVA  361
            GV TG+YAINPVNG EMP+W+ADYVL SYGTGAIMAVPAHDERD EFA+ F L I  V+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGNIDDEAYTGDGEHVNSEFLNGLGKEEAITKMIDWLEANGSGEKKITYRLRDWLFARQR  421
            GGN+++ A+T DG H+NS+FL+GL+K  AI+KM++WLEA+G G+ ++TYRLRDWLF+RQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPIIHWEDGTMTAVPDEDLPLTLPQVAEIKPSGTGESPLANNTDWVNVVDPETGL  481
            YWGEPIPIIHWEDGT TAVP+ +LPL LP   +I+PSGTGESPLAN TDW++V   E G+
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT-REDGV  482

Query  482  KGRRETNTMPQWAGSCWYFLRYIDPNNTERLADPKALEEWLPIDIYIGGAEHAVLHLLYA  541
            KGRRETNTMPQWAGS WY+LRYIDP+NTE+LAD   L +WLP+DIY+GGAEHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKFLFDIGVVSTKEPFQKLYNQGMILG------------------------------  571
            RFWHK L+D+GVV+TKEPFQKL+NQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---EGNEKMSKSKGNVVNPDDIIDSHGADTLRLYEMFMGPLDASVAWSTNGLDGSRRFLD  628
               ++  KMSKS  NVVNPDD+++  GADTLR+YEMFMGPLDAS+AWS +GL+GSR+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RVWRLYVGDDGSLTDKIIDDESTELDKIYHETVKKVTDDFEHMHFNTGISQMMVFINECY  688
            RV RL    +      I +++S  LDK+Y+ETVK VT++ ++M FNT+I+Q+MVF+N   
Sbjct  663  RVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  689  KANKIPKIYAEGFVKLLSPVAPHLSEEIWQKL-GHSESISKATWPAYDESKLVEDEVEVV  747
            K +K+   YA GFV+L++P APHL+EE+WQ L + +ESIS   WP+YDESKLVE++VE+V
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  748  LQIMGKVRSKIQVPVDISKDDLEKAALDDESMQKWLEGKTIRKVIVVPGKLVNIVAN  804
            +QI GKV++K+ V+ D+S+++L+  AL +E +Q  + GK I KVI VP KLVNIV +
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

186) leuS in NC_021171


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  939 bits (3556),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 548/837 (66%), Positives = 668/837 (80%), Gaps = 42/837 (5%)

Query  3    FDHQDIEKKWQTYWEENKTFKTSEEKGKRKFYALDMFPYPSGAGLHVGHPEGYTATDILS  62
            +DH  IE KWQ++W +N TFKT+ + +K KFYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RLKRMQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTKKNIDNFRRQIKSLGFSYDWDR  122
            R+KR QG NVLHPMGWDAFGLPAEQYA+DTGNDPAEFT  NI NF+RQI++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVNTTDQSYYKWTQWIFLQLYKKGLAYIDEVAVNWCPALGTVLANEEVI-DGKSERGGHP  181
            EVNTTD +YYKWTQWIF +LY KGLAY  EV+VNW   LGT +ANEEV+ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRPMKQWMLRITAYADRLLEDLDEVDWPESIKEMQRNWIGRSEGAEITFHIDGYDETF  241
            V R+PM+QWML+ITAYA+RLLEDL+EVDWPESIK+MQRNWIG+S GA++TF + + D  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  TVFTTRPDTLFGATYAVLAPEHPLVGVISTDSQKEAVKVYLDQIKSKSDLERTDLAKDKT  301
            TVFTTRPDTLFGATYAVLAPEH+LV+ I+T  Q EAV  Y  Q   KSDL RTDLAK+KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAINPVNGEKMPIWIADYVLMSYGSGAIMAVPAHDERDYEFAKKFELPIIEVVG  361
            GV TG+YAINPVNG  MP+WIADYVL SYG+GAIMAVPAHDERD EFAK+F+L II V+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGDISTEAYTGDGDHVNSEFLNGMNKVDGIQAMISWLEERKIGMKKVTYRLRDWLFSRQR  421
            GG++   A+T DG H+NS+FL+G++K  +I  M+ WLE   +G  +VTYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPIIHWEDGTMSAVPEDQLPLVLPKTSEIKPSGTGESPLAIIKDWVNIEDPTTGK  481
            YWGEPIPIIHWEDGT +AVPE +LPLVLP T +I+PSGTGESPLA + DW+++     G 
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV-TREDGV  482

Query  482  KGRRETNTMPQWAGSCWYYLRYIDPKNDQALADAEKLNEWLPVDIYIGGAEHAVLHLLYA  541
            KGRRETNTMPQWAGS WYYLRYIDP N + LAD E L++WLPVDIY+GGAEHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKFLYDIGVVPTKEPFQKLFNQGMILG------------------------------  571
            RFWHK LYD+GVVPTKEPFQKLFNQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---EGNEKMSKSKGNVVNPDDIVISHGADTLRLYEMFMGPLDASIAWSTNGLDGSRRFLD  628
               ++  KMSKS  NVVNPDD+V   GADTLR+YEMFMGPLDASIAWS +GL+GSR+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RIWRLFIEDTGELSSKIQTSDDDTLEKVYHQTVKKVTEDYEGLRFNTAISQMMVFINDAY  688
            R+ RL+       +  I   + ++L+KVY++TVK VTE+ + ++FNTAI+Q+MVF+N A 
Sbjct  663  RVYRLIT------TKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  689  KATVLPKHFIEGFVKLLAPITPHVAEELWSKLGGKG-TISYEAWPAYDEAKLIDDEVEIV  747
            K   L  ++  GFV+L+AP++PH++EELW  L + G +ISY +WP+YDE+KL++++VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  748  VQINGKVKAKLLVPSGASKEILEQIAMDDDNIKEQIDGKTVRKVIAVPGKLVNIVAN  804
            VQI+GKVKAKL+V+ + S+E L+++A+ +++++ +I GK + KVIAVP KLVNIV +
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

187) leuS in NC_016011


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  938 bits (3553),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 562/836 (68%), Positives = 690/836 (83%), Gaps = 41/836 (4%)

Query  41   FNHKKVEPKWQQYWSEHNTFKTTEDKNKENFYALDMFPYPSGAGLHVGHPEGYTATDILS  100
            ++H  +EPKWQ +W++++TFKT  D +K +FYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  101  RMKRMQGKNVLHPIGWDAFGLPAEQYAIDTGNDPEEFTALNIANFTRQIKSLGFSYDWER  160
            R KR QG NVLHP+GWDAFGLPAEQYA+DTGNDP EFTA NIANF RQI++LGFSYDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  161  EINTTDPEYYKWTQWIFEKLYENGLAYEAEIAVNWCPALGTVLANEEVI-DGKSERGGFP  219
            E+NTTDP+YYKWTQWIF KLYE+GLAYEAE++VNW   LGT +ANEEV+ DG SERGG+P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  220  VFRKPMRQWMLKITAYAdrllddldlvdWPENIKDMQRNWIGRSEGAEVTFKMKDSDETF  279
            V RKPMRQWMLKITAYA+RLL+DL+ VDWPE+IKDMQRNWIG+S GA+VTFK+KD+D  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  280  NVFTTRPDTLFGATYTVFAPEHELIEKITTAAQKDAVEAYKKQVELKSELERTDLAKDKT  339
             VFTTRPDTLFGATY+V+APEH L++ ITT+ Q +AV  YK+Q  LKS+L RTDLAK+KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  340  GVFTGAYAINPINGEEVPVWIADYVLIQYGTGAIMAVPAHDERDYEFAKQFGLNIRPVLE  399
            GV TG+YAINP+NG E+PVWIADYVL  YGTGAIMAVPAHDERD EFAKQF L+I PVLE
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  400  GGDVTKEAFTGDGPHINSGFLNGLDKTEAITAAIDWLEKEGIGNRKITYRLRDWLFSRQR  459
            GG+V   AFT DG HINS+FL+GLDK+ AI+  ++WLE EG+GN ++TYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  460  YWGEPIPVIHWEDGettlvpeeelplllpkateIKPSGTGESPLANLHDWVNVTDENGRK  519
            YWGEPIP+IHWEDG +T VPE ELPL+LP + +I+PSGTGESPLAN+ DW++VT E+G K
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  520  GRRETNTMPQWAGSSWYFLRYIDPTNTKAIADKEKLAEWLPVDVYIGGAEHAVLHLLYAR  579
            GRRETNTMPQWAGSSWY+LRYIDP NT  +AD E L +WLPVD+Y+GGAEHAVLHLLYAR
Sbjct  484  GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYAR  543

Query  580  FWHKFLYDIGVVPTKEPFQKLFNQGMILG-------------------------------  608
            FWHK LYD+GVVPTKEPFQKLFNQGMILG                               
Sbjct  544  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEE  603

Query  609  --ENNEKMSKSRGNVVNPDEVVEKYGADTLRLYEMFMGPLEASIAWNENGLEGARKFLDR  666
              +   KMSKS  NVVNPD+VVE+YGADTLR+YEMFMGPL+ASIAW+E+GLEG+RKFLDR
Sbjct  604  LEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR  663

Query  667  IWRLLVTEEGTLAEKVTTDANANLEKAYHHMVKTVTNHYENLRFNTGISQLMIFINEAYK  726
            + RL+ T E      +T + ++ L+K Y++ VK+VT++ ++++FNT+I+QLM+F+N A K
Sbjct  664  VYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANK  717

Query  727  QPTIPKEYVEGFVQLLSPIAPHLAEELWEIL-GHTETISYVSWPTYDETKLVEDEVEIVL  785
            +  +  +Y  GFVQL++P+APHL+EELW+ L +  E+ISYV+WP+YDE+KLVE++VEIV+
Sbjct  718  EDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVV  777

Query  786  QVNGKVKNKITVAKSLSKEELETLAKNDDKMKENLENKSIRKIIVVPGKLVNIVAN  841
            Q++GKVK K+ VAK LS+EEL+ +A  ++K++ ++  K I K+I VP KLVNIV +
Sbjct  778  QIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

188) leuS in NC_010382


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  938 bits (3555),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 568/838 (68%), Positives = 683/838 (82%), Gaps = 43/838 (5%)

Query  3    FNHQQIEKKWQQYWADNKTFKTENETEKPKFFALDMFPYPSGAGLHVGHPEGYTATDILS  62
            ++H  IE KWQ +WADN TFKT  ++ KPKF+ALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RFKRMQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTAKNIATFKRQIQELGFSYDWDR  122
            RFKR QG NVLHPMGWDAFGLPAEQYA+DTGNDPAEFTA NIA FKRQI+ LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EINTTDPAYYKWTQWIFIQLYKKGLAYVDEVAVNWCPALGTVLANEEVI-DGKSERGGHP  181
            E+NTTDP YYKWTQWIF +LY KGLAY  EV+VNW   LGT +ANEEV+ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRPMKQWMLKITAYADRLIDDLEEVDWPESIKDMQRNWIGRSEGAEVTFGIDGTDENF  241
            V R+PM+QWMLKITAYA+RL++DLEEVDWPESIKDMQRNWIG+S GA+VTF + +TD +F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  TVFTTRPDTLFGATYCVLAPEHKLVEQITTVEQRQAVEDYLEKVKMKSDLERTDLAKEKT  301
            TVFTTRPDTLFGATY VLAPEH LV+ ITT +Q +AV DY  +  +KSDL RTDLAKEKT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAVNPINGKKVPIWIADYVLVSYGTGAIMAVPAHDERDYEFASAFSLDIVPVLE  361
            GV TG+YA+NP+NGK +P+WIADYVL SYGTGAIMAVPAHDERD EFA  F+LDI+PVLE
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGDISKEAFTGDGQHINSDFLNGLNKVEGIAKAIEWLEEKGVGEKKISYRLRDWLFSRQR  421
            GG++   AFT DG HINSDFL+GL+K  +IAK +EWLE  GVG+ +++YRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPMIHWEDGTITPVpeeelplmlpKTDNIRPSGTGESPLANIAEWVNVVDPATGK  481
            YWGEPIP+IHWEDGT T+VPE ELPL+LP T +IRPSGTGESPLAN+++W++V     G 
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT-REDGV  482

Query  482  KGRRETNTMPQWAGSSWYFLRYIDPTNTEAIADPELLKRWLPVDIYIGGAEHAVLHLLYA  541
            KGRRETNTMPQWAGSSWY+LRYIDP NTE +AD ELLK+WLPVDIY+GGAEHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKVLYDLGVVHTKEPFQKLFNQGMILG------------------------------  571
            RFWHKVLYDLGVV TKEPFQKLFNQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---EGNEKMSKSKGNVVNPDEIIESHGSDTLRLYEMFMGPLEASVAWSTNGLDGARRFLD  628
               ++  KMSKS  NVVNPD+++E  G+DTLR+YEMFMGPL+AS+AWS +GL+G+R+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RIWRLLVNEEDGTISAKIQVSDDKTLEKSYHQTVKKVTEDYEGIRFNTAISQMMVFINDC  688
            R+ RL+   E       I   +  +L+K Y++TVK VTE+ + ++FNTAI+Q+MVF+N  
Sbjct  663  RVYRLITTKE-------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAA  715

Query  689  YKAEVIPTAYAEGFVKMLAPIAPHIAEELWNLLGHEG-TLSYEQWPTYDESKLvddevev  747
             K + + + YA GFV+++AP+APH++EELW+ L   G ++SY  WP+YDESKLV+++VE+
Sbjct  716  NKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEI  775

Query  748  avqvaGKVRAKIVVAKDASKEDIEKVALADEKVQEYMAGKDLVKVIVIPGKLVNIVVK  805
             VQ+ GKV+AK+VVAKD S+E+++ VALA+EKVQ  +AGKD++KVI +P KLVNIV+K
Sbjct  776  VVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

189) leuS in NC_018081


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  937 bits (3551),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 591/837 (71%), Positives = 693/837 (83%), Gaps = 42/837 (5%)

Query  3    YNHKEIEKKWQKYWAKNNTFNTHDDPEKPKFYAMDMFPYPSGQGLHVGHPEGYTATDILS  62
            Y+H  IE KWQ +WA N+TF+T  D+ KPKFYA+DMFPYPSG GLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RFKRSQGFNVLHPMGWDAFGLPAEQYALDTGNDPAEFTQKNIETFRRQINSLGFSYDWNR  122
            RFKR+QG NVLHPMGWDAFGLPAEQYA+DTGNDPAEFT  NI  F+RQIN+LGFSYDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVNTTDPEYYKWTQWIFTKLYEKGLAYEAEVAVNWVPELGTVISNEEVI-DGKSERGGYD  181
            EVNTTDP+YYKWTQWIFTKLYEKGLAYEAEV+VNWV ELGT I+NEEV+ DG SERGGY 
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VVRKPMRQWMLKITAYAdrllddldlvdwpdSIKEMQRNWIGRSVGANVEFKVAGTDKTY  241
            VVRKPMRQWMLKITAYA+RLL+DL+ VDWP+SIK+MQRNWIG+S GANV FKV +TDK +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  TIFTTRPDTLFGATYSVLAPELDLVQEITTPEQKAAVEAYIEETAKKSDLKRTDLAKEKT  301
            T+FTTRPDTLFGATY+VLAPE  LV+ ITT++Q  AV  Y  +++ KSDL RTDLAKEKT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAINPVNGKEIPIWIADYVLASYGTGAIMAVPAHDERDYEFAKTFDLEILPVIE  361
            GV TG+YAINPVNGKE+P+WIADYVLASYGTGAIMAVPAHDERD EFAK F+L+I+PV+E
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGNIEEAAYTEDGPHINSEFLNGMNKAEAIAKMNEWLEENSCGKKEVSYRLRDWLFSRQR  421
            GGN+EEAA+TEDG HINS+FL+G++KA AIAKM EWLE ++ G+ +V+YRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPIIHWEDGTVTAlpeeelplrlpKTTNIKPSGTGESPLANIEEWVNVVDPVTGK  481
            YWGEPIPIIHWEDGT TA+PE ELPL LP T +I+PSGTGESPLAN+ +W++V     G 
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRE-DGV  482

Query  482  KGRRETNTMPQWAGSSWYYLRYIDPHNKTELANYEKLERWLPVDIYIGGAEHAVLHLLYA  541
            KGRRETNTMPQWAGSSWYYLRYIDPHN   LA+ E L +WLPVDIY+GGAEHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKFLYDIGVVPTKEPFQKLYNQGMILG------------------------------  571
            RFWHK LYD+GVVPTKEPFQKL+NQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---ENNEKMSKSRGNVVNPDDVVAKYGADTLRLYEMFMGPLDASIAWSENGLEGSRKFLD  628
               +   KMSKS  NVVNPDDVV +YGADTLR+YEMFMGPLDASIAWSE+GLEGSRKFLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RVWRLIVDENNKMRDRITTLNDGKLDKVYHQTVKKVTEDYENLHFNTAISQLMVFVNEAY  688
            RV RLI   +      IT  N G LDKVY++TVK VTE+ +++ FNTAI+QLMVFVN A 
Sbjct  663  RVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  689  KVDALPYEYIEGFVQLLAPIAPHMGEELWAIL-GNEEGISYAAWPTYDESALVEDEIEVV  747
            K D L  +Y  GFVQL+AP+APH+GEELW  L ++ E+ISY +WP+YDES LVE+++E+V
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  748  FQINGKVRGKANVSRDLPKDELEKIAMNNETIKENIAGKTVRKVIVVPNKLVNIVAN  804
             QI+GKV++K  V++DL+++EL+ +A+ NE ++ +IAGK + KVI VPNKLVNIV +
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

190) leuS in NC_012659


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  935 bits (3544),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 559/837 (67%), Positives = 668/837 (80%), Gaps = 44/837 (5%)

Query  3    FNHQEIEKKWQGYWEENKTFRTPDETEKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  62
            ++H  IE KWQ++W +N TF+T  ++ KPKFYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMKRMQGYNVLHPMGWDAFGLPAEQYALDTGNSPAEFTEHNINTFRNQIKSLGFSYDWDR  122
            R KR QG NVLHPMGWDAFGLPAEQYA+DTGN PAEFT +NI  F+ QI++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVNTTDPNYYKWTQWIFLKLFEKGLAYVDEVPVNWCPALGTVLANEEII-DGKSERGGHP  181
            EVNTTDPNYYKWTQWIF KL+EKGLAY  EVPVNW   LGT +ANEE++ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRPMRQWMLKITAYGdrlledldeldWPESLKDMQRNWIGRSEGAEVHFNIDGTDEKF  241
            V R+PMRQWMLKITAY++RLLEDL+E+DWPES+KDMQRNWIG+S GA+V F++ +TD  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  TVFTTRPDTLFGASYCVLAPEHALVADITTADQKEAVEAYINSVKMKSDLERTELAKEKT  301
            TVFTTRPDTLFGA+Y VLAPEHALV  ITT+DQ EAV  Y     +KSDL RT+LAKEKT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAVNPVNGEKLPIWIADYVLATYGTGAVMAVPAHDERDYEFASTFNLPMKEVVK  361
            GV TG+YA+NPVNG  +P+WIADYVLA+YGTGA+MAVPAHDERD EFA  FNL +  V+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGDITKEAYTGDGAHVNSAFLDGLNKEEAIAKMIEWLEVTSAGNQKVTYRLRDWLFSRQR  421
            GG++   A+T DG H+NS FLDGL+K  AIAKM+EWLE  + GN++VTYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPVIHWEDGTMTAVKEEELPLVLPKTENIRPSGTGESPLANIDEWVNVVDPETGK  481
            YWGEPIP+IHWEDGT TAV E ELPLVLP T +IRPSGTGESPLAN+ +W++V   E G 
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT-REDGV  482

Query  482  KGRRETNTMPQWAGSCWYYLRYIDPNNSEALVDPEKVKQWLPVDIYIGGAEHAVLHLLYA  541
            KGRRETNTMPQWAGS WYYLRYIDP+N+E L D E +KQWLPVDIY+GGAEHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKVLYDIGVVPTKEPFQQLFNQGMILG------------------------------  571
            RFWHKVLYD+GVVPTKEPFQ+LFNQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---ENNEKMSKSKGNVVNPDDIVASHGADTLRLYEMFMGPLDASIAWSENGLDGARRFLD  628
               +   KMSKS  NVVNPDD+V   GADTLR+YEMFMGPLDASIAWSE+GL+G+R+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RVWRLFVQDNGELSEKITDAPNKDLEKAYHQTVKKVTEDYAELRFNTAISQMMVFINDAY  688
            RV RL+       +  IT+  +  L+K Y++TVK VTE+  +++FNTAI+Q+MVF+N A 
Sbjct  663  RVYRLIT------TKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  689  KAETLPKEYVEGFVKMIAPVAPHIGEELWSKL-GYNETITYASWPTFDESKLVEDEVEIV  747
            K + L  +Y  GFV++IAP APH+GEELW  L +  E+I+Y +WP++DESKLVE++VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  748  VQVMGKVRAKLTMSKDASKDEMEKLAL--EAIQDQIEGKTVRKVIVVPGKLVNVVAN  802
            VQ+ GKV+AKL ++KD S++E++ +AL  E +Q +I GK + KVI VP KLVN+V +
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

191) leuS in NC_007530


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  935 bits (3544),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 559/837 (67%), Positives = 668/837 (80%), Gaps = 44/837 (5%)

Query  3    FNHQEIEKKWQGYWEENKTFRTPDETEKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  62
            ++H  IE KWQ++W +N TF+T  ++ KPKFYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMKRMQGYNVLHPMGWDAFGLPAEQYALDTGNSPAEFTEHNINTFRNQIKSLGFSYDWDR  122
            R KR QG NVLHPMGWDAFGLPAEQYA+DTGN PAEFT +NI  F+ QI++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVNTTDPNYYKWTQWIFLKLFEKGLAYVDEVPVNWCPALGTVLANEEII-DGKSERGGHP  181
            EVNTTDPNYYKWTQWIF KL+EKGLAY  EVPVNW   LGT +ANEE++ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRPMRQWMLKITAYGdrlledldeldWPESLKDMQRNWIGRSEGAEVHFNIDGTDEKF  241
            V R+PMRQWMLKITAY++RLLEDL+E+DWPES+KDMQRNWIG+S GA+V F++ +TD  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  TVFTTRPDTLFGASYCVLAPEHALVADITTADQKEAVEAYINSVKMKSDLERTELAKEKT  301
            TVFTTRPDTLFGA+Y VLAPEHALV  ITT+DQ EAV  Y     +KSDL RT+LAKEKT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAVNPVNGEKLPIWIADYVLATYGTGAVMAVPAHDERDYEFASTFNLPMKEVVK  361
            GV TG+YA+NPVNG  +P+WIADYVLA+YGTGA+MAVPAHDERD EFA  FNL +  V+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGDITKEAYTGDGAHVNSAFLDGLNKEEAIAKMIEWLEVTSAGNQKVTYRLRDWLFSRQR  421
            GG++   A+T DG H+NS FLDGL+K  AIAKM+EWLE  + GN++VTYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPVIHWEDGTMTAVKEEELPLVLPKTENIRPSGTGESPLANIDEWVNVVDPETGK  481
            YWGEPIP+IHWEDGT TAV E ELPLVLP T +IRPSGTGESPLAN+ +W++V   E G 
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT-REDGV  482

Query  482  KGRRETNTMPQWAGSCWYYLRYIDPNNSEALVDPEKVKQWLPVDIYIGGAEHAVLHLLYA  541
            KGRRETNTMPQWAGS WYYLRYIDP+N+E L D E +KQWLPVDIY+GGAEHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKVLYDIGVVPTKEPFQQLFNQGMILG------------------------------  571
            RFWHKVLYD+GVVPTKEPFQ+LFNQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---ENNEKMSKSKGNVVNPDDIVASHGADTLRLYEMFMGPLDASIAWSENGLDGARRFLD  628
               +   KMSKS  NVVNPDD+V   GADTLR+YEMFMGPLDASIAWSE+GL+G+R+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RVWRLFVQDNGELSEKITDAPNKDLEKAYHQTVKKVTEDYAELRFNTAISQMMVFINDAY  688
            RV RL+       +  IT+  +  L+K Y++TVK VTE+  +++FNTAI+Q+MVF+N A 
Sbjct  663  RVYRLIT------TKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  689  KAETLPKEYVEGFVKMIAPVAPHIGEELWSKL-GYNETITYASWPTFDESKLVEDEVEIV  747
            K + L  +Y  GFV++IAP APH+GEELW  L +  E+I+Y +WP++DESKLVE++VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  748  VQVMGKVRAKLTMSKDASKDEMEKLAL--EAIQDQIEGKTVRKVIVVPGKLVNVVAN  802
            VQ+ GKV+AKL ++KD S++E++ +AL  E +Q +I GK + KVI VP KLVN+V +
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

192) leuS in NC_003997


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  935 bits (3544),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 559/837 (67%), Positives = 668/837 (80%), Gaps = 44/837 (5%)

Query  3    FNHQEIEKKWQGYWEENKTFRTPDETEKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  62
            ++H  IE KWQ++W +N TF+T  ++ KPKFYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMKRMQGYNVLHPMGWDAFGLPAEQYALDTGNSPAEFTEHNINTFRNQIKSLGFSYDWDR  122
            R KR QG NVLHPMGWDAFGLPAEQYA+DTGN PAEFT +NI  F+ QI++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVNTTDPNYYKWTQWIFLKLFEKGLAYVDEVPVNWCPALGTVLANEEII-DGKSERGGHP  181
            EVNTTDPNYYKWTQWIF KL+EKGLAY  EVPVNW   LGT +ANEE++ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRPMRQWMLKITAYGdrlledldeldWPESLKDMQRNWIGRSEGAEVHFNIDGTDEKF  241
            V R+PMRQWMLKITAY++RLLEDL+E+DWPES+KDMQRNWIG+S GA+V F++ +TD  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  TVFTTRPDTLFGASYCVLAPEHALVADITTADQKEAVEAYINSVKMKSDLERTELAKEKT  301
            TVFTTRPDTLFGA+Y VLAPEHALV  ITT+DQ EAV  Y     +KSDL RT+LAKEKT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAVNPVNGEKLPIWIADYVLATYGTGAVMAVPAHDERDYEFASTFNLPMKEVVK  361
            GV TG+YA+NPVNG  +P+WIADYVLA+YGTGA+MAVPAHDERD EFA  FNL +  V+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGDITKEAYTGDGAHVNSAFLDGLNKEEAIAKMIEWLEVTSAGNQKVTYRLRDWLFSRQR  421
            GG++   A+T DG H+NS FLDGL+K  AIAKM+EWLE  + GN++VTYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPVIHWEDGTMTAVKEEELPLVLPKTENIRPSGTGESPLANIDEWVNVVDPETGK  481
            YWGEPIP+IHWEDGT TAV E ELPLVLP T +IRPSGTGESPLAN+ +W++V   E G 
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT-REDGV  482

Query  482  KGRRETNTMPQWAGSCWYYLRYIDPNNSEALVDPEKVKQWLPVDIYIGGAEHAVLHLLYA  541
            KGRRETNTMPQWAGS WYYLRYIDP+N+E L D E +KQWLPVDIY+GGAEHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKVLYDIGVVPTKEPFQQLFNQGMILG------------------------------  571
            RFWHKVLYD+GVVPTKEPFQ+LFNQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---ENNEKMSKSKGNVVNPDDIVASHGADTLRLYEMFMGPLDASIAWSENGLDGARRFLD  628
               +   KMSKS  NVVNPDD+V   GADTLR+YEMFMGPLDASIAWSE+GL+G+R+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RVWRLFVQDNGELSEKITDAPNKDLEKAYHQTVKKVTEDYAELRFNTAISQMMVFINDAY  688
            RV RL+       +  IT+  +  L+K Y++TVK VTE+  +++FNTAI+Q+MVF+N A 
Sbjct  663  RVYRLIT------TKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  689  KAETLPKEYVEGFVKMIAPVAPHIGEELWSKL-GYNETITYASWPTFDESKLVEDEVEIV  747
            K + L  +Y  GFV++IAP APH+GEELW  L +  E+I+Y +WP++DESKLVE++VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  748  VQVMGKVRAKLTMSKDASKDEMEKLAL--EAIQDQIEGKTVRKVIVVPGKLVNVVAN  802
            VQ+ GKV+AKL ++KD S++E++ +AL  E +Q +I GK + KVI VP KLVN+V +
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

193) leuS in NC_012581


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  935 bits (3544),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 559/837 (67%), Positives = 668/837 (80%), Gaps = 44/837 (5%)

Query  3    FNHQEIEKKWQGYWEENKTFRTPDETEKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  62
            ++H  IE KWQ++W +N TF+T  ++ KPKFYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMKRMQGYNVLHPMGWDAFGLPAEQYALDTGNSPAEFTEHNINTFRNQIKSLGFSYDWDR  122
            R KR QG NVLHPMGWDAFGLPAEQYA+DTGN PAEFT +NI  F+ QI++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVNTTDPNYYKWTQWIFLKLFEKGLAYVDEVPVNWCPALGTVLANEEII-DGKSERGGHP  181
            EVNTTDPNYYKWTQWIF KL+EKGLAY  EVPVNW   LGT +ANEE++ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRPMRQWMLKITAYGdrlledldeldWPESLKDMQRNWIGRSEGAEVHFNIDGTDEKF  241
            V R+PMRQWMLKITAY++RLLEDL+E+DWPES+KDMQRNWIG+S GA+V F++ +TD  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  TVFTTRPDTLFGASYCVLAPEHALVADITTADQKEAVEAYINSVKMKSDLERTELAKEKT  301
            TVFTTRPDTLFGA+Y VLAPEHALV  ITT+DQ EAV  Y     +KSDL RT+LAKEKT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAVNPVNGEKLPIWIADYVLATYGTGAVMAVPAHDERDYEFASTFNLPMKEVVK  361
            GV TG+YA+NPVNG  +P+WIADYVLA+YGTGA+MAVPAHDERD EFA  FNL +  V+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGDITKEAYTGDGAHVNSAFLDGLNKEEAIAKMIEWLEVTSAGNQKVTYRLRDWLFSRQR  421
            GG++   A+T DG H+NS FLDGL+K  AIAKM+EWLE  + GN++VTYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPVIHWEDGTMTAVKEEELPLVLPKTENIRPSGTGESPLANIDEWVNVVDPETGK  481
            YWGEPIP+IHWEDGT TAV E ELPLVLP T +IRPSGTGESPLAN+ +W++V   E G 
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT-REDGV  482

Query  482  KGRRETNTMPQWAGSCWYYLRYIDPNNSEALVDPEKVKQWLPVDIYIGGAEHAVLHLLYA  541
            KGRRETNTMPQWAGS WYYLRYIDP+N+E L D E +KQWLPVDIY+GGAEHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKVLYDIGVVPTKEPFQQLFNQGMILG------------------------------  571
            RFWHKVLYD+GVVPTKEPFQ+LFNQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---ENNEKMSKSKGNVVNPDDIVASHGADTLRLYEMFMGPLDASIAWSENGLDGARRFLD  628
               +   KMSKS  NVVNPDD+V   GADTLR+YEMFMGPLDASIAWSE+GL+G+R+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RVWRLFVQDNGELSEKITDAPNKDLEKAYHQTVKKVTEDYAELRFNTAISQMMVFINDAY  688
            RV RL+       +  IT+  +  L+K Y++TVK VTE+  +++FNTAI+Q+MVF+N A 
Sbjct  663  RVYRLIT------TKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  689  KAETLPKEYVEGFVKMIAPVAPHIGEELWSKL-GYNETITYASWPTFDESKLVEDEVEIV  747
            K + L  +Y  GFV++IAP APH+GEELW  L +  E+I+Y +WP++DESKLVE++VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  748  VQVMGKVRAKLTMSKDASKDEMEKLAL--EAIQDQIEGKTVRKVIVVPGKLVNVVAN  802
            VQ+ GKV+AKL ++KD S++E++ +AL  E +Q +I GK + KVI VP KLVN+V +
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

194) H9401_4769 in NC_017729


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  935 bits (3544),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 559/837 (67%), Positives = 668/837 (80%), Gaps = 44/837 (5%)

Query  3    FNHQEIEKKWQGYWEENKTFRTPDETEKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  62
            ++H  IE KWQ++W +N TF+T  ++ KPKFYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMKRMQGYNVLHPMGWDAFGLPAEQYALDTGNSPAEFTEHNINTFRNQIKSLGFSYDWDR  122
            R KR QG NVLHPMGWDAFGLPAEQYA+DTGN PAEFT +NI  F+ QI++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVNTTDPNYYKWTQWIFLKLFEKGLAYVDEVPVNWCPALGTVLANEEII-DGKSERGGHP  181
            EVNTTDPNYYKWTQWIF KL+EKGLAY  EVPVNW   LGT +ANEE++ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRPMRQWMLKITAYGdrlledldeldWPESLKDMQRNWIGRSEGAEVHFNIDGTDEKF  241
            V R+PMRQWMLKITAY++RLLEDL+E+DWPES+KDMQRNWIG+S GA+V F++ +TD  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  TVFTTRPDTLFGASYCVLAPEHALVADITTADQKEAVEAYINSVKMKSDLERTELAKEKT  301
            TVFTTRPDTLFGA+Y VLAPEHALV  ITT+DQ EAV  Y     +KSDL RT+LAKEKT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAVNPVNGEKLPIWIADYVLATYGTGAVMAVPAHDERDYEFASTFNLPMKEVVK  361
            GV TG+YA+NPVNG  +P+WIADYVLA+YGTGA+MAVPAHDERD EFA  FNL +  V+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGDITKEAYTGDGAHVNSAFLDGLNKEEAIAKMIEWLEVTSAGNQKVTYRLRDWLFSRQR  421
            GG++   A+T DG H+NS FLDGL+K  AIAKM+EWLE  + GN++VTYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPVIHWEDGTMTAVKEEELPLVLPKTENIRPSGTGESPLANIDEWVNVVDPETGK  481
            YWGEPIP+IHWEDGT TAV E ELPLVLP T +IRPSGTGESPLAN+ +W++V   E G 
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT-REDGV  482

Query  482  KGRRETNTMPQWAGSCWYYLRYIDPNNSEALVDPEKVKQWLPVDIYIGGAEHAVLHLLYA  541
            KGRRETNTMPQWAGS WYYLRYIDP+N+E L D E +KQWLPVDIY+GGAEHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKVLYDIGVVPTKEPFQQLFNQGMILG------------------------------  571
            RFWHKVLYD+GVVPTKEPFQ+LFNQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---ENNEKMSKSKGNVVNPDDIVASHGADTLRLYEMFMGPLDASIAWSENGLDGARRFLD  628
               +   KMSKS  NVVNPDD+V   GADTLR+YEMFMGPLDASIAWSE+GL+G+R+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RVWRLFVQDNGELSEKITDAPNKDLEKAYHQTVKKVTEDYAELRFNTAISQMMVFINDAY  688
            RV RL+       +  IT+  +  L+K Y++TVK VTE+  +++FNTAI+Q+MVF+N A 
Sbjct  663  RVYRLIT------TKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  689  KAETLPKEYVEGFVKMIAPVAPHIGEELWSKL-GYNETITYASWPTFDESKLVEDEVEIV  747
            K + L  +Y  GFV++IAP APH+GEELW  L +  E+I+Y +WP++DESKLVE++VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  748  VQVMGKVRAKLTMSKDASKDEMEKLAL--EAIQDQIEGKTVRKVIVVPGKLVNVVAN  802
            VQ+ GKV+AKL ++KD S++E++ +AL  E +Q +I GK + KVI VP KLVN+V +
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

195) leuS in NC_005945


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  935 bits (3544),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 559/837 (67%), Positives = 668/837 (80%), Gaps = 44/837 (5%)

Query  3    FNHQEIEKKWQGYWEENKTFRTPDETEKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  62
            ++H  IE KWQ++W +N TF+T  ++ KPKFYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMKRMQGYNVLHPMGWDAFGLPAEQYALDTGNSPAEFTEHNINTFRNQIKSLGFSYDWDR  122
            R KR QG NVLHPMGWDAFGLPAEQYA+DTGN PAEFT +NI  F+ QI++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVNTTDPNYYKWTQWIFLKLFEKGLAYVDEVPVNWCPALGTVLANEEII-DGKSERGGHP  181
            EVNTTDPNYYKWTQWIF KL+EKGLAY  EVPVNW   LGT +ANEE++ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRPMRQWMLKITAYGdrlledldeldWPESLKDMQRNWIGRSEGAEVHFNIDGTDEKF  241
            V R+PMRQWMLKITAY++RLLEDL+E+DWPES+KDMQRNWIG+S GA+V F++ +TD  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  TVFTTRPDTLFGASYCVLAPEHALVADITTADQKEAVEAYINSVKMKSDLERTELAKEKT  301
            TVFTTRPDTLFGA+Y VLAPEHALV  ITT+DQ EAV  Y     +KSDL RT+LAKEKT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAVNPVNGEKLPIWIADYVLATYGTGAVMAVPAHDERDYEFASTFNLPMKEVVK  361
            GV TG+YA+NPVNG  +P+WIADYVLA+YGTGA+MAVPAHDERD EFA  FNL +  V+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGDITKEAYTGDGAHVNSAFLDGLNKEEAIAKMIEWLEVTSAGNQKVTYRLRDWLFSRQR  421
            GG++   A+T DG H+NS FLDGL+K  AIAKM+EWLE  + GN++VTYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPVIHWEDGTMTAVKEEELPLVLPKTENIRPSGTGESPLANIDEWVNVVDPETGK  481
            YWGEPIP+IHWEDGT TAV E ELPLVLP T +IRPSGTGESPLAN+ +W++V   E G 
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT-REDGV  482

Query  482  KGRRETNTMPQWAGSCWYYLRYIDPNNSEALVDPEKVKQWLPVDIYIGGAEHAVLHLLYA  541
            KGRRETNTMPQWAGS WYYLRYIDP+N+E L D E +KQWLPVDIY+GGAEHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKVLYDIGVVPTKEPFQQLFNQGMILG------------------------------  571
            RFWHKVLYD+GVVPTKEPFQ+LFNQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---ENNEKMSKSKGNVVNPDDIVASHGADTLRLYEMFMGPLDASIAWSENGLDGARRFLD  628
               +   KMSKS  NVVNPDD+V   GADTLR+YEMFMGPLDASIAWSE+GL+G+R+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RVWRLFVQDNGELSEKITDAPNKDLEKAYHQTVKKVTEDYAELRFNTAISQMMVFINDAY  688
            RV RL+       +  IT+  +  L+K Y++TVK VTE+  +++FNTAI+Q+MVF+N A 
Sbjct  663  RVYRLIT------TKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  689  KAETLPKEYVEGFVKMIAPVAPHIGEELWSKL-GYNETITYASWPTFDESKLVEDEVEIV  747
            K + L  +Y  GFV++IAP APH+GEELW  L +  E+I+Y +WP++DESKLVE++VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  748  VQVMGKVRAKLTMSKDASKDEMEKLAL--EAIQDQIEGKTVRKVIVVPGKLVNVVAN  802
            VQ+ GKV+AKL ++KD S++E++ +AL  E +Q +I GK + KVI VP KLVN+V +
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

196) leuS in NC_012472


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  935 bits (3544),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 559/837 (67%), Positives = 668/837 (80%), Gaps = 44/837 (5%)

Query  3    FNHQEIEKKWQGYWEENKTFRTPDETEKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  62
            ++H  IE KWQ++W +N TF+T  ++ KPKFYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMKRMQGYNVLHPMGWDAFGLPAEQYALDTGNSPAEFTEHNINTFRNQIKSLGFSYDWDR  122
            R KR QG NVLHPMGWDAFGLPAEQYA+DTGN PAEFT +NI  F+ QI++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVNTTDPNYYKWTQWIFLKLFEKGLAYVDEVPVNWCPALGTVLANEEII-DGKSERGGHP  181
            EVNTTDPNYYKWTQWIF KL+EKGLAY  EVPVNW   LGT +ANEE++ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRPMRQWMLKITAYGdrlledldeldWPESLKDMQRNWIGRSEGAEVHFNIDGTDEKF  241
            V R+PMRQWMLKITAY++RLLEDL+E+DWPES+KDMQRNWIG+S GA+V F++ +TD  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  TVFTTRPDTLFGASYCVLAPEHALVADITTADQKEAVEAYINSVKMKSDLERTELAKEKT  301
            TVFTTRPDTLFGA+Y VLAPEHALV  ITT+DQ EAV  Y     +KSDL RT+LAKEKT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAVNPVNGEKLPIWIADYVLATYGTGAVMAVPAHDERDYEFASTFNLPMKEVVK  361
            GV TG+YA+NPVNG  +P+WIADYVLA+YGTGA+MAVPAHDERD EFA  FNL +  V+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGDITKEAYTGDGAHVNSAFLDGLNKEEAIAKMIEWLEVTSAGNQKVTYRLRDWLFSRQR  421
            GG++   A+T DG H+NS FLDGL+K  AIAKM+EWLE  + GN++VTYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPVIHWEDGTMTAVKEEELPLVLPKTENIRPSGTGESPLANIDEWVNVVDPETGK  481
            YWGEPIP+IHWEDGT TAV E ELPLVLP T +IRPSGTGESPLAN+ +W++V   E G 
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT-REDGV  482

Query  482  KGRRETNTMPQWAGSCWYYLRYIDPNNSEALVDPEKVKQWLPVDIYIGGAEHAVLHLLYA  541
            KGRRETNTMPQWAGS WYYLRYIDP+N+E L D E +KQWLPVDIY+GGAEHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKVLYDIGVVPTKEPFQQLFNQGMILG------------------------------  571
            RFWHKVLYD+GVVPTKEPFQ+LFNQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---ENNEKMSKSKGNVVNPDDIVASHGADTLRLYEMFMGPLDASIAWSENGLDGARRFLD  628
               +   KMSKS  NVVNPDD+V   GADTLR+YEMFMGPLDASIAWSE+GL+G+R+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RVWRLFVQDNGELSEKITDAPNKDLEKAYHQTVKKVTEDYAELRFNTAISQMMVFINDAY  688
            RV RL+       +  IT+  +  L+K Y++TVK VTE+  +++FNTAI+Q+MVF+N A 
Sbjct  663  RVYRLIT------TKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  689  KAETLPKEYVEGFVKMIAPVAPHIGEELWSKL-GYNETITYASWPTFDESKLVEDEVEIV  747
            K + L  +Y  GFV++IAP APH+GEELW  L +  E+I+Y +WP++DESKLVE++VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  748  VQVMGKVRAKLTMSKDASKDEMEKLAL--EAIQDQIEGKTVRKVIVVPGKLVNVVAN  802
            VQ+ GKV+AKL ++KD S++E++ +AL  E +Q +I GK + KVI VP KLVN+V +
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

197) leuS in NC_011773


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  935 bits (3544),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 559/837 (67%), Positives = 668/837 (80%), Gaps = 44/837 (5%)

Query  3    FNHQEIEKKWQGYWEENKTFRTPDETEKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  62
            ++H  IE KWQ++W +N TF+T  ++ KPKFYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMKRMQGYNVLHPMGWDAFGLPAEQYALDTGNSPAEFTEHNINTFRNQIKSLGFSYDWDR  122
            R KR QG NVLHPMGWDAFGLPAEQYA+DTGN PAEFT +NI  F+ QI++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVNTTDPNYYKWTQWIFLKLFEKGLAYVDEVPVNWCPALGTVLANEEII-DGKSERGGHP  181
            EVNTTDPNYYKWTQWIF KL+EKGLAY  EVPVNW   LGT +ANEE++ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRPMRQWMLKITAYGdrlledldeldWPESLKDMQRNWIGRSEGAEVHFNIDGTDEKF  241
            V R+PMRQWMLKITAY++RLLEDL+E+DWPES+KDMQRNWIG+S GA+V F++ +TD  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  TVFTTRPDTLFGASYCVLAPEHALVADITTADQKEAVEAYINSVKMKSDLERTELAKEKT  301
            TVFTTRPDTLFGA+Y VLAPEHALV  ITT+DQ EAV  Y     +KSDL RT+LAKEKT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAVNPVNGEKLPIWIADYVLATYGTGAVMAVPAHDERDYEFASTFNLPMKEVVK  361
            GV TG+YA+NPVNG  +P+WIADYVLA+YGTGA+MAVPAHDERD EFA  FNL +  V+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGDITKEAYTGDGAHVNSAFLDGLNKEEAIAKMIEWLEVTSAGNQKVTYRLRDWLFSRQR  421
            GG++   A+T DG H+NS FLDGL+K  AIAKM+EWLE  + GN++VTYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPVIHWEDGTMTAVKEEELPLVLPKTENIRPSGTGESPLANIDEWVNVVDPETGK  481
            YWGEPIP+IHWEDGT TAV E ELPLVLP T +IRPSGTGESPLAN+ +W++V   E G 
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT-REDGV  482

Query  482  KGRRETNTMPQWAGSCWYYLRYIDPNNSEALVDPEKVKQWLPVDIYIGGAEHAVLHLLYA  541
            KGRRETNTMPQWAGS WYYLRYIDP+N+E L D E +KQWLPVDIY+GGAEHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKVLYDIGVVPTKEPFQQLFNQGMILG------------------------------  571
            RFWHKVLYD+GVVPTKEPFQ+LFNQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---ENNEKMSKSKGNVVNPDDIVASHGADTLRLYEMFMGPLDASIAWSENGLDGARRFLD  628
               +   KMSKS  NVVNPDD+V   GADTLR+YEMFMGPLDASIAWSE+GL+G+R+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RVWRLFVQDNGELSEKITDAPNKDLEKAYHQTVKKVTEDYAELRFNTAISQMMVFINDAY  688
            RV RL+       +  IT+  +  L+K Y++TVK VTE+  +++FNTAI+Q+MVF+N A 
Sbjct  663  RVYRLIT------TKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  689  KAETLPKEYVEGFVKMIAPVAPHIGEELWSKL-GYNETITYASWPTFDESKLVEDEVEIV  747
            K + L  +Y  GFV++IAP APH+GEELW  L +  E+I+Y +WP++DESKLVE++VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  748  VQVMGKVRAKLTMSKDASKDEMEKLAL--EAIQDQIEGKTVRKVIVVPGKLVNVVAN  802
            VQ+ GKV+AKL ++KD S++E++ +AL  E +Q +I GK + KVI VP KLVN+V +
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

198) leuS in NC_004722


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  935 bits (3543),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 560/837 (67%), Positives = 669/837 (80%), Gaps = 44/837 (5%)

Query  3    FNHQEIEKKWQGYWEENKTFRTPDETEKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  62
            ++H  IE KWQ++W +N TF+T  ++ KPKFYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMKRMQGYNVLHPMGWDAFGLPAEQYALDTGNSPAEFTEHNINTFRNQIKSLGFSYDWDR  122
            R KR QG NVLHPMGWDAFGLPAEQYA+DTGN PAEFT +NI  F+ QI++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVNTTDPNYYKWTQWIFLKLFEKGLAYVDEVPVNWCPALGTVLANEEII-DGKSERGGHP  181
            EVNTTDPNYYKWTQWIF KL+EKGLAY  EVPVNW   LGT +ANEE++ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRPMRQWMLKITAYGdrlledldeldWPESLKDMQRNWIGRSEGAEVHFNIDGTDEKF  241
            V R+PMRQWMLKITAY++RLLEDL+E+DWPES+KDMQRNWIG+S GA+V F++ +TD  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  TVFTTRPDTLFGATYCVLAPEHALVAEITTAEQKEAVEAYINAVKMKSDLERTELAKEKT  301
            TVFTTRPDTLFGATY VLAPEHALV  ITT++Q EAV  Y     +KSDL RT+LAKEKT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAVNPVNGEKLPIWIADYVLATYGTGAVMAVPAHDERDYEFASVFNLPMKEVVK  361
            GV TG+YA+NPVNG  +P+WIADYVLA+YGTGA+MAVPAHDERD EFA  FNL +  V+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGDITKEVYTGDGAHVNSAFLDGLNKEEAIAKMIEWLEATSAGNQKVTYRLRDWLFSRQR  421
            GG++    +T DG H+NS FLDGL+K  AIAKM+EWLEA + GN++VTYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPVIHWEDGTMTAVKEEELPLVLPKTENIRPSGTGESPLANIDEWVNVVDPETGK  481
            YWGEPIP+IHWEDGT TAV E ELPLVLP T +IRPSGTGESPLAN+ +W++V   E G 
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT-REDGV  482

Query  482  KGRRETNTMPQWAGSCWYYLRYIDPNNSEALVDPEKVKQWLPVDIYIGGAEHAVLHLLYA  541
            KGRRETNTMPQWAGS WYYLRYIDP+N+E L D E +KQWLPVDIY+GGAEHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKVLYDIGVVPTKEPFQQLFNQGMILG------------------------------  571
            RFWHKVLYD+GVVPTKEPFQ+LFNQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---ENNEKMSKSKGNVVNPDDIVASHGADTLRLYEMFMGPLDASIAWSENGLDGARRFLD  628
               +   KMSKS  NVVNPDD+V   GADTLR+YEMFMGPLDASIAWSE+GL+G+R+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RVWRLFVQDNGELSEKITDAPNKELEKAYHQTVKKVTEDYAELRFNTAISQMMVFINDAY  688
            RV RL+       +  IT+  +  L+K Y++TVK VTE+  +++FNTAI+Q+MVF+N A 
Sbjct  663  RVYRLIT------TKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  689  KAETLPREYVEGFVKMIAPVAPHIGEELWSKL-GYNETITYASWPTFDESKLVEDEVEIV  747
            K + L  +Y  GFV++IAP APH+GEELW  L +  E+I+Y +WP++DESKLVE++VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  748  VQVMGKVRAKLTMSKDASKEEMEQLAL--EAIQDQIEGKTVRKVIVVPGKLVNVVAN  802
            VQ+ GKV+AKL ++KD S+EE++++AL  E +Q +I GK + KVI VP KLVN+V +
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

199) leuS in NC_006274


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  935 bits (3544),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 559/837 (67%), Positives = 668/837 (80%), Gaps = 44/837 (5%)

Query  3    FNHQEIEKKWQGYWEENKTFRTPDETEKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  62
            ++H  IE KWQ++W +N TF+T  ++ KPKFYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMKRMQGYNVLHPMGWDAFGLPAEQYALDTGNSPAEFTEHNINTFRNQIKSLGFSYDWDR  122
            R KR QG NVLHPMGWDAFGLPAEQYA+DTGN PAEFT +NI  F+ QI++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVNTTDPNYYKWTQWIFLKLFEKGLAYVDEVPVNWCPALGTVLANEEII-DGKSERGGHP  181
            EVNTTDPNYYKWTQWIF KL+EKGLAY  EVPVNW   LGT +ANEE++ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRPMRQWMLKITAYGdrlledldeldWPESLKDMQRNWIGRSEGAEVHFNIDGTDEKF  241
            V R+PMRQWMLKITAY++RLLEDL+E+DWPES+KDMQRNWIG+S GA+V F++ +TD  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  TVFTTRPDTLFGASYCVLAPEHALVADITTADQKEAVEAYINSVKMKSDLERTELAKEKT  301
            TVFTTRPDTLFGA+Y VLAPEHALV  ITT+DQ EAV  Y     +KSDL RT+LAKEKT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAVNPVNGEKLPIWIADYVLATYGTGAVMAVPAHDERDYEFASTFNLPMKEVVK  361
            GV TG+YA+NPVNG  +P+WIADYVLA+YGTGA+MAVPAHDERD EFA  FNL +  V+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGDITKEAYTGDGAHVNSAFLDGLNKEEAIAKMIEWLEVTSAGNQKVTYRLRDWLFSRQR  421
            GG++   A+T DG H+NS FLDGL+K  AIAKM+EWLE  + GN++VTYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPVIHWEDGTMTAVKEEELPLVLPKTENIRPSGTGESPLANIDEWVNVVDPETGK  481
            YWGEPIP+IHWEDGT TAV E ELPLVLP T +IRPSGTGESPLAN+ +W++V   E G 
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT-REDGV  482

Query  482  KGRRETNTMPQWAGSCWYYLRYIDPNNSEALVDPEKVKQWLPVDIYIGGAEHAVLHLLYA  541
            KGRRETNTMPQWAGS WYYLRYIDP+N+E L D E +KQWLPVDIY+GGAEHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKVLYDIGVVPTKEPFQQLFNQGMILG------------------------------  571
            RFWHKVLYD+GVVPTKEPFQ+LFNQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---ENNEKMSKSKGNVVNPDDIVASHGADTLRLYEMFMGPLDASIAWSENGLDGARRFLD  628
               +   KMSKS  NVVNPDD+V   GADTLR+YEMFMGPLDASIAWSE+GL+G+R+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RVWRLFVQDNGELSEKITDAPNKDLEKAYHQTVKKVTEDYAELRFNTAISQMMVFINDAY  688
            RV RL+       +  IT+  +  L+K Y++TVK VTE+  +++FNTAI+Q+MVF+N A 
Sbjct  663  RVYRLIT------TKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  689  KAETLPKEYVEGFVKMIAPVAPHIGEELWSKL-GYNETITYASWPTFDESKLVEDEVEIV  747
            K + L  +Y  GFV++IAP APH+GEELW  L +  E+I+Y +WP++DESKLVE++VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  748  VQVMGKVRAKLTMSKDASKDEMEKLAL--EAIQDQIEGKTVRKVIVVPGKLVNVVAN  802
            VQ+ GKV+AKL ++KD S++E++ +AL  E +Q +I GK + KVI VP KLVN+V +
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

200) bcf_23780 in NC_016779


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  935 bits (3544),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 559/837 (67%), Positives = 668/837 (80%), Gaps = 44/837 (5%)

Query  3    FNHQEIEKKWQGYWEENKTFRTPDETEKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  62
            ++H  IE KWQ++W +N TF+T  ++ KPKFYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMKRMQGYNVLHPMGWDAFGLPAEQYALDTGNSPAEFTEHNINTFRNQIKSLGFSYDWDR  122
            R KR QG NVLHPMGWDAFGLPAEQYA+DTGN PAEFT +NI  F+ QI++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVNTTDPNYYKWTQWIFLKLFEKGLAYVDEVPVNWCPALGTVLANEEII-DGKSERGGHP  181
            EVNTTDPNYYKWTQWIF KL+EKGLAY  EVPVNW   LGT +ANEE++ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRPMRQWMLKITAYGdrlledldeldWPESLKDMQRNWIGRSEGAEVHFNIDGTDEKF  241
            V R+PMRQWMLKITAY++RLLEDL+E+DWPES+KDMQRNWIG+S GA+V F++ +TD  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  TVFTTRPDTLFGASYCVLAPEHALVADITTADQKEAVEAYINSVKMKSDLERTELAKEKT  301
            TVFTTRPDTLFGA+Y VLAPEHALV  ITT+DQ EAV  Y     +KSDL RT+LAKEKT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAVNPVNGEKLPIWIADYVLATYGTGAVMAVPAHDERDYEFASTFNLPMKEVVK  361
            GV TG+YA+NPVNG  +P+WIADYVLA+YGTGA+MAVPAHDERD EFA  FNL +  V+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGDITKEAYTGDGAHVNSAFLDGLNKEEAIAKMIEWLEVTSAGNQKVTYRLRDWLFSRQR  421
            GG++   A+T DG H+NS FLDGL+K  AIAKM+EWLE  + GN++VTYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPVIHWEDGTMTAVKEEELPLVLPKTENIRPSGTGESPLANIDEWVNVVDPETGK  481
            YWGEPIP+IHWEDGT TAV E ELPLVLP T +IRPSGTGESPLAN+ +W++V   E G 
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT-REDGV  482

Query  482  KGRRETNTMPQWAGSCWYYLRYIDPNNSEALVDPEKVKQWLPVDIYIGGAEHAVLHLLYA  541
            KGRRETNTMPQWAGS WYYLRYIDP+N+E L D E +KQWLPVDIY+GGAEHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKVLYDIGVVPTKEPFQQLFNQGMILG------------------------------  571
            RFWHKVLYD+GVVPTKEPFQ+LFNQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---ENNEKMSKSKGNVVNPDDIVASHGADTLRLYEMFMGPLDASIAWSENGLDGARRFLD  628
               +   KMSKS  NVVNPDD+V   GADTLR+YEMFMGPLDASIAWSE+GL+G+R+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RVWRLFVQDNGELSEKITDAPNKDLEKAYHQTVKKVTEDYAELRFNTAISQMMVFINDAY  688
            RV RL+       +  IT+  +  L+K Y++TVK VTE+  +++FNTAI+Q+MVF+N A 
Sbjct  663  RVYRLIT------TKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  689  KAETLPKEYVEGFVKMIAPVAPHIGEELWSKL-GYNETITYASWPTFDESKLVEDEVEIV  747
            K + L  +Y  GFV++IAP APH+GEELW  L +  E+I+Y +WP++DESKLVE++VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  748  VQVMGKVRAKLTMSKDASKDEMEKLAL--EAIQDQIEGKTVRKVIVVPGKLVNVVAN  802
            VQ+ GKV+AKL ++KD S++E++ +AL  E +Q +I GK + KVI VP KLVN+V +
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

201) leuS in NC_018491


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  935 bits (3542),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 558/837 (67%), Positives = 669/837 (80%), Gaps = 44/837 (5%)

Query  3    FNHQEIEKKWQGYWEENKTFRTPDETEKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  62
            ++H  IE KWQ++W +N TF+T  ++ KPKFYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMKRMQGYNVLHPMGWDAFGLPAEQYALDTGNSPAEFTEHNINTFRNQIKSLGFSYDWDR  122
            R KR QG NVLHPMGWDAFGLPAEQYA+DTGN PAEFT +NI  F+ QI++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVNTTDPNYYKWTQWIFLKLFEKGLAYVDEVPVNWCPALGTVLANEEII-DGKSERGGHP  181
            EVNTTDPNYYKWTQWIF KL+EKGLAY  EVPVNW   LGT +ANEE++ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRPMRQWMLKITAYGdrlledldeldWPESLKDMQRNWIGRSEGAEVHFNIDGTDEKF  241
            V R+PMRQWMLKITAY++RLLEDL+E+DWPES+KDMQRNWIG+S GA+V F++ +TD  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  TVFTTRPDTLFGASYCVLAPEHALVADITTAEQKEAVEAYINSVKMKSDLERTELAKEKT  301
            TVFTTRPDTLFGA+Y VLAPEHALV  ITT++Q EAV  Y     +KSDL RT+LAKEKT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAVNPVNGEKLPIWIADYVLATYGTGAVMAVPAHDERDYEFASTFNLPMKEVVK  361
            GV TG+YA+NPVNG  +P+WIADYVLA+YGTGA+MAVPAHDERD EFA  FNL +  V+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGDITKEAYTGDGAHVNSAFLDGLNKEEAIAKMIEWLEVTSAGNQKVTYRLRDWLFSRQR  421
            GG++   A+T DG H+NS FLDGL+K  AIAKM+EWLE  + GN++VTYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPVIHWEDGTMTAVKEEELPLVLPKTDNIRPSGTGESPLANIDEWVNVVDPETGK  481
            YWGEPIP+IHWEDGT TAV E ELPLVLP T +IRPSGTGESPLAN+ +W++V   E G 
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT-REDGV  482

Query  482  KGRRETNTMPQWAGSCWYYLRYIDPNNSEALVDPEKVKQWLPVDIYIGGAEHAVLHLLYA  541
            KGRRETNTMPQWAGS WYYLRYIDP+N+E L D E +KQWLPVDIY+GGAEHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKVLYDIGVVPTKEPFQQLFNQGMILG------------------------------  571
            RFWHKVLYD+GVVPTKEPFQ+LFNQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---ENNEKMSKSKGNVVNPDDIVASHGADTLRLYEMFMGPLDASIAWSENGLDGARRFLD  628
               +   KMSKS  NVVNPDD+V   GADTLR+YEMFMGPLDASIAWSE+GL+G+R+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RVWRLFVQDNGELSEKITDAPNKELEKAYHQTVKKVTEDYAELRFNTAISQMMVFINDAY  688
            RV RL+       +  IT+  +  L+K Y++TVK VTE+  +++FNTAI+Q+MVF+N A 
Sbjct  663  RVYRLIT------TKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  689  KAETLPKEYVEGFVKMIAPVAPHIGEELWSKL-GYNETITYASWPTFDESKLVEDEVEIV  747
            K + L  +Y  GFV++IAP APH+GEELW  L +  E+I+Y +WP++DESKLVE++VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  748  VQVMGKVRAKLTMSKDASKEEMEQLAL--EAIKDQIEGKTVRKVIVVPGKLVNVVAN  802
            VQ+ GKV+AKL ++KD S+EE++++AL  E ++ +I GK + KVI VP KLVN+V +
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

202) leuS in NC_008600


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  935 bits (3544),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 559/837 (67%), Positives = 668/837 (80%), Gaps = 44/837 (5%)

Query  3    FNHQEIEKKWQGYWEENKTFRTPDETEKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  62
            ++H  IE KWQ++W +N TF+T  ++ KPKFYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMKRMQGYNVLHPMGWDAFGLPAEQYALDTGNSPAEFTEHNINTFRNQIKSLGFSYDWDR  122
            R KR QG NVLHPMGWDAFGLPAEQYA+DTGN PAEFT +NI  F+ QI++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVNTTDPNYYKWTQWIFLKLFEKGLAYVDEVPVNWCPALGTVLANEEII-DGKSERGGHP  181
            EVNTTDPNYYKWTQWIF KL+EKGLAY  EVPVNW   LGT +ANEE++ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRPMRQWMLKITAYGdrlledldeldWPESLKDMQRNWIGRSEGAEVHFNIDGTDEKF  241
            V R+PMRQWMLKITAY++RLLEDL+E+DWPES+KDMQRNWIG+S GA+V F++ +TD  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  TVFTTRPDTLFGASYCVLAPEHALVADITTADQKEAVEAYINSVKMKSDLERTELAKEKT  301
            TVFTTRPDTLFGA+Y VLAPEHALV  ITT+DQ EAV  Y     +KSDL RT+LAKEKT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAVNPVNGEKLPIWIADYVLATYGTGAVMAVPAHDERDYEFASTFNLPMKEVVK  361
            GV TG+YA+NPVNG  +P+WIADYVLA+YGTGA+MAVPAHDERD EFA  FNL +  V+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGDITKEAYTGDGAHVNSAFLDGLNKEEAIAKMIEWLEVTSAGNQKVTYRLRDWLFSRQR  421
            GG++   A+T DG H+NS FLDGL+K  AIAKM+EWLE  + GN++VTYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPVIHWEDGTMTAVKEEELPLVLPKTENIRPSGTGESPLANIDEWVNVVDPETGK  481
            YWGEPIP+IHWEDGT TAV E ELPLVLP T +IRPSGTGESPLAN+ +W++V   E G 
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT-REDGV  482

Query  482  KGRRETNTMPQWAGSCWYYLRYIDPNNSEALVDPEKVKQWLPVDIYIGGAEHAVLHLLYA  541
            KGRRETNTMPQWAGS WYYLRYIDP+N+E L D E +KQWLPVDIY+GGAEHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKVLYDIGVVPTKEPFQQLFNQGMILG------------------------------  571
            RFWHKVLYD+GVVPTKEPFQ+LFNQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---ENNEKMSKSKGNVVNPDDIVASHGADTLRLYEMFMGPLDASIAWSENGLDGARRFLD  628
               +   KMSKS  NVVNPDD+V   GADTLR+YEMFMGPLDASIAWSE+GL+G+R+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RVWRLFVQDNGELSEKITDAPNKDLEKAYHQTVKKVTEDYAELRFNTAISQMMVFINDAY  688
            RV RL+       +  IT+  +  L+K Y++TVK VTE+  +++FNTAI+Q+MVF+N A 
Sbjct  663  RVYRLIT------TKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  689  KAETLPKEYVEGFVKMIAPVAPHIGEELWSKL-GYNETITYASWPTFDESKLVEDEVEIV  747
            K + L  +Y  GFV++IAP APH+GEELW  L +  E+I+Y +WP++DESKLVE++VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  748  VQVMGKVRAKLTMSKDASKDEMEKLAL--EAIQDQIEGKTVRKVIVVPGKLVNVVAN  802
            VQ+ GKV+AKL ++KD S++E++ +AL  E +Q +I GK + KVI VP KLVN+V +
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

203) leuS in NC_014171


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  935 bits (3543),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 560/837 (67%), Positives = 669/837 (80%), Gaps = 44/837 (5%)

Query  3    FNHQEIEKKWQGYWEENKTFRTPDETEKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  62
            ++H  IE KWQ++W +N TF+T  ++ KPKFYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMKRMQGYNVLHPMGWDAFGLPAEQYALDTGNSPAEFTEHNINTFRNQIKSLGFSYDWDR  122
            R KR QG NVLHPMGWDAFGLPAEQYA+DTGN PAEFT +NI  F+ QI++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVNTTDPNYYKWTQWIFLKLFEKGLAYVDEVPVNWCPALGTVLANEEII-DGKSERGGHP  181
            EVNTTDPNYYKWTQWIF KL+EKGLAY  EVPVNW   LGT +ANEE++ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRPMRQWMLKITAYGdrlledldeldWPESLKDMQRNWIGRSEGAEVHFNIDGTDEKF  241
            V R+PMRQWMLKITAY++RLLEDL+E+DWPES+KDMQRNWIG+S GA+V F++ +TD  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  TVFTTRPDTLFGATYCVLAPEHALVAEITTAEQKEAVEAYINAVKMKSDLERTELAKEKT  301
            TVFTTRPDTLFGATY VLAPEHALV  ITT++Q EAV  Y     +KSDL RT+LAKEKT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAVNPVNGEKLPIWIADYVLATYGTGAVMAVPAHDERDYEFASVFNLPMKEVVK  361
            GV TG+YA+NPVNG  +P+WIADYVLA+YGTGA+MAVPAHDERD EFA  FNL +  V+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGDITKEVYTGDGAHVNSAFLDGLNKEEAIAKMIEWLEATSAGNQKVTYRLRDWLFSRQR  421
            GG++    +T DG H+NS FLDGL+K  AIAKM+EWLEA + GN++VTYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPVIHWEDGTMTAVKEEELPLVLPKTENIRPSGTGESPLANIDEWVNVVDPETGK  481
            YWGEPIP+IHWEDGT TAV E ELPLVLP T +IRPSGTGESPLAN+ +W++V   E G 
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT-REDGV  482

Query  482  KGRRETNTMPQWAGSCWYYLRYIDPNNSEALVDPEKVKQWLPVDIYIGGAEHAVLHLLYA  541
            KGRRETNTMPQWAGS WYYLRYIDP+N+E L D E +KQWLPVDIY+GGAEHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKVLYDIGVVPTKEPFQQLFNQGMILG------------------------------  571
            RFWHKVLYD+GVVPTKEPFQ+LFNQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---ENNEKMSKSKGNVVNPDDIVASHGADTLRLYEMFMGPLDASIAWSENGLDGARRFLD  628
               +   KMSKS  NVVNPDD+V   GADTLR+YEMFMGPLDASIAWSE+GL+G+R+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RVWRLFVQDNGELSEKITDAPNKELEKAYHQTVKKVTEDYAELRFNTAISQMMVFINDAY  688
            RV RL+       +  IT+  +  L+K Y++TVK VTE+  +++FNTAI+Q+MVF+N A 
Sbjct  663  RVYRLIT------TKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  689  KAETLPREYVEGFVKMIAPVAPHIGEELWSKL-GYNETITYASWPTFDESKLVEDEVEIV  747
            K + L  +Y  GFV++IAP APH+GEELW  L +  E+I+Y +WP++DESKLVE++VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  748  VQVMGKVRAKLTMSKDASKEEMEQLAL--EAIQDQIEGKTVRKVIVVPGKLVNVVAN  802
            VQ+ GKV+AKL ++KD S+EE++++AL  E +Q +I GK + KVI VP KLVN+V +
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

204) leuS in NC_018877


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  935 bits (3544),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 560/837 (67%), Positives = 669/837 (80%), Gaps = 44/837 (5%)

Query  3    FNHQEIEKKWQGYWEENKTFRTPDETEKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  62
            ++H  IE KWQ++W +N TF+T  ++ KPKFYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMKRMQGYNVLHPMGWDAFGLPAEQYALDTGNSPAEFTEHNINTFRNQIKSLGFSYDWDR  122
            R KR QG NVLHPMGWDAFGLPAEQYA+DTGN PAEFT +NI  F+ QI++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVNTTDPNYYKWTQWIFLKLFEKGLAYVDEVPVNWCPALGTVLANEEII-DGKSERGGHP  181
            EVNTTDPNYYKWTQWIF KL+EKGLAY  EVPVNW   LGT +ANEE++ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRPMRQWMLKITAYGdrlledldeldWPESLKDMQRNWIGRSEGAEVHFNIDGTDEKF  241
            V R+PMRQWMLKITAY++RLLEDL+E+DWPES+KDMQRNWIG+S GA+V F++ +TD  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  TVFTTRPDTLFGATYCVLAPEHALVAEITTAEQKEAVEAYINAVKMKSDLERTELAKEKT  301
            TVFTTRPDTLFGATY VLAPEHALV  ITT++Q EAV  Y     +KSDL RT+LAKEKT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAVNPVNGEKLPIWIADYVLATYGTGAVMAVPAHDERDYEFASVFNLPMKEVVK  361
            GV TG+YA+NPVNG  +P+WIADYVLA+YGTGA+MAVPAHDERD EFA  FNL +  V+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGDITKEVYTGDGAHVNSAFLDGLNKEEAIAKMIEWLEATSAGNQKVTYRLRDWLFSRQR  421
            GG++    +T DG H+NS FLDGL+K  AIAKM+EWLEA + GN++VTYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPVIHWEDGTMTAVKEEELPLVLPKTENIRPSGTGESPLANIDEWVNVVDPETGK  481
            YWGEPIP+IHWEDGT TAV E ELPLVLP T +IRPSGTGESPLAN+ +W++V   E G 
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT-REDGV  482

Query  482  KGRRETNTMPQWAGSCWYYLRYIDPNNSEALVDPEKVKQWLPVDIYIGGAEHAVLHLLYA  541
            KGRRETNTMPQWAGS WYYLRYIDP+N+E L D E +KQWLPVDIY+GGAEHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKVLYDIGVVPTKEPFQQLFNQGMILG------------------------------  571
            RFWHKVLYD+GVVPTKEPFQ+LFNQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---ENNEKMSKSKGNVVNPDDIVASHGADTLRLYEMFMGPLDASIAWSENGLDGARRFLD  628
               +   KMSKS  NVVNPDD+V   GADTLR+YEMFMGPLDASIAWSE+GL+G+R+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RVWRLFVQDNGELSEKITDAPNKELEKAYHQTVKKVTEDYAELRFNTAISQMMVFINDAY  688
            RV RL+       +  IT+  +  L+K Y++TVK VTE+  +++FNTAI+Q+MVF+N A 
Sbjct  663  RVYRLIT------TKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  689  KAETLPKEYVEGFVKMIAPVAPHIGEELWSKL-GYNETITYASWPTFDESKLVEDEVEIV  747
            K + L  +Y  GFV++IAP APH+GEELW  L +  E+I+Y +WP++DESKLVE++VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  748  VQVMGKVRAKLTMSKDASKEEMEQLAL--EAIQDQIEGKTVRKVIVVPGKLVNVVAN  802
            VQ+ GKV+AKL ++KD S+EE++++AL  E +Q +I GK + KVI VP KLVN+V +
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

205) leuS in NC_017208


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  935 bits (3544),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 560/837 (67%), Positives = 669/837 (80%), Gaps = 44/837 (5%)

Query  3    FNHQEIEKKWQGYWEENKTFRTPDETEKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  62
            ++H  IE KWQ++W +N TF+T  ++ KPKFYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMKRMQGYNVLHPMGWDAFGLPAEQYALDTGNSPAEFTEHNINTFRNQIKSLGFSYDWDR  122
            R KR QG NVLHPMGWDAFGLPAEQYA+DTGN PAEFT +NI  F+ QI++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVNTTDPNYYKWTQWIFLKLFEKGLAYVDEVPVNWCPALGTVLANEEII-DGKSERGGHP  181
            EVNTTDPNYYKWTQWIF KL+EKGLAY  EVPVNW   LGT +ANEE++ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRPMRQWMLKITAYGdrlledldeldWPESLKDMQRNWIGRSEGAEVHFNIDGTDEKF  241
            V R+PMRQWMLKITAY++RLLEDL+E+DWPES+KDMQRNWIG+S GA+V F++ +TD  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  TVFTTRPDTLFGATYCVLAPEHALVAEITTAEQKEAVEAYINAVKMKSDLERTELAKEKT  301
            TVFTTRPDTLFGATY VLAPEHALV  ITT++Q EAV  Y     +KSDL RT+LAKEKT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAVNPVNGEKLPIWIADYVLATYGTGAVMAVPAHDERDYEFASVFNLPMKEVVK  361
            GV TG+YA+NPVNG  +P+WIADYVLA+YGTGA+MAVPAHDERD EFA  FNL +  V+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGDITKEVYTGDGAHVNSAFLDGLNKEEAIAKMIEWLEATSAGNQKVTYRLRDWLFSRQR  421
            GG++    +T DG H+NS FLDGL+K  AIAKM+EWLEA + GN++VTYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPVIHWEDGTMTAVKEEELPLVLPKTENIRPSGTGESPLANIDEWVNVVDPETGK  481
            YWGEPIP+IHWEDGT TAV E ELPLVLP T +IRPSGTGESPLAN+ +W++V   E G 
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT-REDGV  482

Query  482  KGRRETNTMPQWAGSCWYYLRYIDPNNSEALVDPEKVKQWLPVDIYIGGAEHAVLHLLYA  541
            KGRRETNTMPQWAGS WYYLRYIDP+N+E L D E +KQWLPVDIY+GGAEHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKVLYDIGVVPTKEPFQQLFNQGMILG------------------------------  571
            RFWHKVLYD+GVVPTKEPFQ+LFNQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---ENNEKMSKSKGNVVNPDDIVASHGADTLRLYEMFMGPLDASIAWSENGLDGARRFLD  628
               +   KMSKS  NVVNPDD+V   GADTLR+YEMFMGPLDASIAWSE+GL+G+R+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RVWRLFVQDNGELSEKITDAPNKELEKAYHQTVKKVTEDYAELRFNTAISQMMVFINDAY  688
            RV RL+       +  IT+  +  L+K Y++TVK VTE+  +++FNTAI+Q+MVF+N A 
Sbjct  663  RVYRLIT------TKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  689  KAETLPKEYVEGFVKMIAPVAPHIGEELWSKL-GYNETITYASWPTFDESKLVEDEVEIV  747
            K + L  +Y  GFV++IAP APH+GEELW  L +  E+I+Y +WP++DESKLVE++VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  748  VQVMGKVRAKLTMSKDASKEEMEQLAL--EAIQDQIEGKTVRKVIVVPGKLVNVVAN  802
            VQ+ GKV+AKL ++KD S+EE++++AL  E +Q +I GK + KVI VP KLVN+V +
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

206) H175_ch4838 in NC_020376


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  935 bits (3544),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 560/837 (67%), Positives = 669/837 (80%), Gaps = 44/837 (5%)

Query  3    FNHQEIEKKWQGYWEENKTFRTPDETEKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  62
            ++H  IE KWQ++W +N TF+T  ++ KPKFYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMKRMQGYNVLHPMGWDAFGLPAEQYALDTGNSPAEFTEHNINTFRNQIKSLGFSYDWDR  122
            R KR QG NVLHPMGWDAFGLPAEQYA+DTGN PAEFT +NI  F+ QI++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVNTTDPNYYKWTQWIFLKLFEKGLAYVDEVPVNWCPALGTVLANEEII-DGKSERGGHP  181
            EVNTTDPNYYKWTQWIF KL+EKGLAY  EVPVNW   LGT +ANEE++ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRPMRQWMLKITAYGdrlledldeldWPESLKDMQRNWIGRSEGAEVHFNIDGTDEKF  241
            V R+PMRQWMLKITAY++RLLEDL+E+DWPES+KDMQRNWIG+S GA+V F++ +TD  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  TVFTTRPDTLFGATYCVLAPEHALVAEITTAEQKEAVEAYINAVKMKSDLERTELAKEKT  301
            TVFTTRPDTLFGATY VLAPEHALV  ITT++Q EAV  Y     +KSDL RT+LAKEKT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAVNPVNGEKLPIWIADYVLATYGTGAVMAVPAHDERDYEFASVFNLPMKEVVK  361
            GV TG+YA+NPVNG  +P+WIADYVLA+YGTGA+MAVPAHDERD EFA  FNL +  V+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGDITKEVYTGDGAHVNSAFLDGLNKEEAIAKMIEWLEATSAGNQKVTYRLRDWLFSRQR  421
            GG++    +T DG H+NS FLDGL+K  AIAKM+EWLEA + GN++VTYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPVIHWEDGTMTAVKEEELPLVLPKTENIRPSGTGESPLANIDEWVNVVDPETGK  481
            YWGEPIP+IHWEDGT TAV E ELPLVLP T +IRPSGTGESPLAN+ +W++V   E G 
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT-REDGV  482

Query  482  KGRRETNTMPQWAGSCWYYLRYIDPNNSEALVDPEKVKQWLPVDIYIGGAEHAVLHLLYA  541
            KGRRETNTMPQWAGS WYYLRYIDP+N+E L D E +KQWLPVDIY+GGAEHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKVLYDIGVVPTKEPFQQLFNQGMILG------------------------------  571
            RFWHKVLYD+GVVPTKEPFQ+LFNQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---ENNEKMSKSKGNVVNPDDIVASHGADTLRLYEMFMGPLDASIAWSENGLDGARRFLD  628
               +   KMSKS  NVVNPDD+V   GADTLR+YEMFMGPLDASIAWSE+GL+G+R+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RVWRLFVQDNGELSEKITDAPNKELEKAYHQTVKKVTEDYAELRFNTAISQMMVFINDAY  688
            RV RL+       +  IT+  +  L+K Y++TVK VTE+  +++FNTAI+Q+MVF+N A 
Sbjct  663  RVYRLIT------TKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  689  KAETLPKEYVEGFVKMIAPVAPHIGEELWSKL-GYNETITYASWPTFDESKLVEDEVEIV  747
            K + L  +Y  GFV++IAP APH+GEELW  L +  E+I+Y +WP++DESKLVE++VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  748  VQVMGKVRAKLTMSKDASKEEMEQLAL--EAIQDQIEGKTVRKVIVVPGKLVNVVAN  802
            VQ+ GKV+AKL ++KD S+EE++++AL  E +Q +I GK + KVI VP KLVN+V +
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

207) leuS in NC_005957


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  935 bits (3542),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 558/837 (67%), Positives = 668/837 (80%), Gaps = 44/837 (5%)

Query  3    FNHQEIEKKWQGYWEENKTFRTPDETEKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  62
            ++H  IE KWQ++W +N TF+T  ++ KPKFYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMKRMQGYNVLHPMGWDAFGLPAEQYALDTGNSPAEFTEHNINTFRNQIKSLGFSYDWDR  122
            R KR QG NVLHPMGWDAFGLPAEQYA+DTGN PAEFT +NI  F+ QI++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVNTTDPNYYKWTQWIFLKLFEKGLAYVDEVPVNWCPALGTVLANEEII-DGKSERGGHP  181
            EVNTTDPNYYKWTQWIF KL+EKGLAY  EVPVNW   LGT +ANEE++ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRPMRQWMLKITAYGdrlledldeldWPESLKDMQRNWIGRSEGAEVHFNIDGTDEKF  241
            V R+PMRQWMLKITAY++RLLEDL+E+DWPES+KDMQRNWIG+S GA+V F++ +TD  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  TVFTTRPDTLFGASYCVLAPEHALVADITTAEQKEAVEAYINSVKMKSDLERTELAKEKT  301
            TVFTTRPDTLFGA+Y VLAPEHALV  ITT++Q EAV  Y     +KSDL RT+LAKEKT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAVNPVNGEKLPIWIADYVLATYGTGAVMAVPAHDERDYEFASTFNLPMKEVVK  361
            GV TG+YA+NPVNG  +P+WIADYVLA+YGTGA+MAVPAHDERD EFA  FNL +  V+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGDITKEAYTGDGAHVNSAFLDGLNKEEAIAKMIEWLEVTSAGNQKVTYRLRDWLFSRQR  421
            GG++   A+T DG H+NS FLDGL+K  AIAKM+EWLE  + GN++VTYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPVIHWEDGTMTAVKEEELPLVLPKTENIRPSGTGESPLANIDEWVNVVDPETGK  481
            YWGEPIP+IHWEDGT TAV E ELPLVLP T +IRPSGTGESPLAN+ +W++V   E G 
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT-REDGV  482

Query  482  KGRRETNTMPQWAGSCWYYLRYIDPNNSEALVDPEKVKQWLPVDIYIGGAEHAVLHLLYA  541
            KGRRETNTMPQWAGS WYYLRYIDP+N+E L D E +KQWLPVDIY+GGAEHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKVLYDIGVVPTKEPFQQLFNQGMILG------------------------------  571
            RFWHKVLYD+GVVPTKEPFQ+LFNQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---ENNEKMSKSKGNVVNPDDIVASHGADTLRLYEMFMGPLDASIAWSENGLDGARRFLD  628
               +   KMSKS  NVVNPDD+V   GADTLR+YEMFMGPLDASIAWSE+GL+G+R+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RVWRLFVQDNGELSEKITDAPNKDLEKAYHQTVKKVTEDYAELRFNTAISQMMVFINDAY  688
            RV RL+       +  IT+  +  L+K Y++TVK VTE+  +++FNTAI+Q+MVF+N A 
Sbjct  663  RVYRLIT------TKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  689  KAETLPKEYVEGFVKMIAPVAPHIGEELWSKL-GYNETITYASWPTFDESKLVEDEVEIV  747
            K + L  +Y  GFV++IAP APH+GEELW  L +  E+I+Y +WP++DESKLVE++VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  748  VQVMGKVRAKLTMSKDASKDEMEKLAL--EAIQDQIEGKTVRKVIVVPGKLVNVVAN  802
            VQ+ GKV+AKL ++KD S++E++ +AL  E +Q +I GK + KVI VP KLVN+V +
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

208) HD73_5048 in NC_020238


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  935 bits (3542),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 560/837 (67%), Positives = 668/837 (80%), Gaps = 44/837 (5%)

Query  3    FNHQEIEKKWQGYWEENKTFRTPDETEKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  62
            ++H  IE KWQ++W +N TF+T  ++ KPKFYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMKRMQGYNVLHPMGWDAFGLPAEQYALDTGNSPAEFTEHNINTFRNQIKSLGFSYDWDR  122
            R KR QG NVLHPMGWDAFGLPAEQYA+DTGN PAEFT +NI  F+ QI++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVNTTDPNYYKWTQWIFLKLFEKGLAYVDEVPVNWCPALGTVLANEEII-DGKSERGGHP  181
            EVNTTDPNYYKWTQWIF KL+EKGLAY  EVPVNW   LGT +ANEE++ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRPMRQWMLKITAYGdrlledldeldWPESLKDMQRNWIGRSEGAEVHFNIDGTDEKF  241
            V R+PMRQWMLKITAY++RLLEDL+E+DWPES+KDMQRNWIG+S GA+V F++ +TD  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  TVFTTRPDTLFGATYCVLAPEHALVAEITTAEQKEAVEAYINAVKMKSDLERTELAKEKT  301
            TVFTTRPDTLFGATY VLAPEHALV  ITT++Q EAV  Y     +KSDL RT+LAKEKT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAINPVNGEKLPIWIADYVLATYGTGAVMAVPAHDERDYEFASVFNLPMKEVVK  361
            GV TG+YAINPVNG  +P+WIADYVLA+YGTGA+MAVPAHDERD EFA  FNL +  V+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGDITKEVYTGDGAHVNSAFLDGLNKEEAIAKMIEWLEVTSAGNQKVTYRLRDWLFSRQR  421
            GG++    +T DG H+NS FLDGL+K  AIAKM+EWLE  + GN++VTYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPVIHWEDGTMTAVKEEELPLVLPKTENIRPSGTGESPLANIDEWVNVVDPETGK  481
            YWGEPIP+IHWEDGT TAV E ELPLVLP T +IRPSGTGESPLAN+ +W++V   E G 
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT-REDGV  482

Query  482  KGRRETNTMPQWAGSCWYYLRYIDPNNSEALVDPEKVKQWLPVDIYIGGAEHAVLHLLYA  541
            KGRRETNTMPQWAGS WYYLRYIDP+N+E L D E +KQWLPVDIY+GGAEHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKVLYDIGVVPTKEPFQQLFNQGMILG------------------------------  571
            RFWHKVLYD+GVVPTKEPFQ+LFNQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---ENNEKMSKSKGNVVNPDDIVASHGADTLRLYEMFMGPLDASIAWSENGLDGARRFLD  628
               +   KMSKS  NVVNPDD+V   GADTLR+YEMFMGPLDASIAWSE+GL+G+R+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RVWRLFVQDNGELSEKITDAPNKELEKAYHQTVKKVTEDYAELRFNTAISQMMVFINDAY  688
            RV RL+       +  IT+  +  L+K Y++TVK VTE+  +++FNTAI+Q+MVF+N A 
Sbjct  663  RVYRLIT------TKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  689  KAETLPREYVEGFVKMIAPVAPHIGEELWSKL-GYNETITYASWPTFDESKLVEDEVEIV  747
            K + L  +Y  GFV++IAP APH+GEELW  L +  E+I+Y +WP++DESKLVE++VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  748  VQVMGKVRAKLTMSKDASKEEMEQLAL--EAIQDQIEGKTVRKVIVVPGKLVNVVAN  802
            VQ+ GKV+AKL ++KD S+EE++++AL  E +Q +I GK + KVI VP KLVN+V +
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

209) leuS in NC_011658


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  934 bits (3540),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 558/837 (67%), Positives = 669/837 (80%), Gaps = 44/837 (5%)

Query  3    FNHQEIEKKWQGYWEENKTFRTPDETEKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  62
            ++H  IE KWQ++W +N TF+T  ++ KPKFYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMKRMQGYNVLHPMGWDAFGLPAEQYALDTGNSPAEFTEHNINTFRNQIKSLGFSYDWDR  122
            R KR QG NVLHPMGWDAFGLPAEQYA+DTGN PAEFT +NI  F+ QI++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVNTTDPNYYKWTQWIFLKLFEKGLAYVDEVPVNWCPALGTVLANEEII-DGKSERGGHP  181
            EVNTTDPNYYKWTQWIF KL+EKGLAY  EVPVNW   LGT +ANEE++ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRPMRQWMLKITAYGdrlledldeldWPESLKDMQRNWIGRSEGAEVHFNIDGTDEKF  241
            V R+PMRQWMLKITAY++RLLEDL+E+DWPES+KDMQRNWIG+S GA+V F++ +TD  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  TVFTTRPDTLFGASYCVLAPEHALVADITTAEQKEAVEAYINSVKMKSDLERTELAKEKT  301
            TVFTTRPDTLFGA+Y VLAPEHALV  ITT++Q EAV  Y     +KSDL RT+LAKEKT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAVNPVNGEKLPIWIADYVLATYGTGAVMAVPAHDERDYEFASTFNLPMKEVVK  361
            GV TG+YA+NPVNG  +P+WIADYVLA+YGTGA+MAVPAHDERD EFA  FNL +  V+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGDITKEAYTGDGEHVNSAFLDGLNKEEAIAKMIEWLEVTSAGNQKVTYRLRDWLFSRQR  421
            GG++   A+T DG H+NS FLDGL+K  AIAKM+EWLE  + GN++VTYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPVIHWEDGTMTAVKEEELPLVLPKTDNIRPSGTGESPLANIDEWVNVVDPETGK  481
            YWGEPIP+IHWEDGT TAV E ELPLVLP T +IRPSGTGESPLAN+ +W++V   E G 
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT-REDGV  482

Query  482  KGRRETNTMPQWAGSCWYYLRYIDPNNSEALVDPEKVKQWLPVDIYIGGAEHAVLHLLYA  541
            KGRRETNTMPQWAGS WYYLRYIDP+N+E L D E +KQWLPVDIY+GGAEHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKVLYDIGVVPTKEPFQQLFNQGMILG------------------------------  571
            RFWHKVLYD+GVVPTKEPFQ+LFNQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---ENNEKMSKSKGNVVNPDDIVASHGADTLRLYEMFMGPLDASIAWSENGLDGARRFLD  628
               +   KMSKS  NVVNPDD+V   GADTLR+YEMFMGPLDASIAWSE+GL+G+R+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RVWRLFVQDNGELSEKITDAPNKELEKAYHQTVKKVTEDYAELRFNTAISQMMVFINDAY  688
            RV RL+       +  IT+  +  L+K Y++TVK VTE+  +++FNTAI+Q+MVF+N A 
Sbjct  663  RVYRLIT------TKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  689  KAETLPKEYVEGFVKMIAPVAPHIGEELWSKL-GYNETITYASWPTFDESKLVEDEVEIV  747
            K + L  +Y  GFV++IAP APH+GEELW  L +  E+I+Y +WP++DESKLVE++VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  748  VQVMGKVRAKLTMSKDASKEEMEQLAL--EAIKDQIEGKTVRKVIVVPGKLVNVVAN  802
            VQ+ GKV+AKL ++KD S+EE++++AL  E ++ +I GK + KVI VP KLVN+V +
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

210) leuS in NC_003909


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  934 bits (3540),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 558/837 (67%), Positives = 669/837 (80%), Gaps = 44/837 (5%)

Query  3    FNHQEIEKKWQGYWEENKTFRTPDETEKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  62
            ++H  IE KWQ++W +N TF+T  ++ KPKFYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMKRMQGYNVLHPMGWDAFGLPAEQYALDTGNSPAEFTEHNINTFRNQIKSLGFSYDWDR  122
            R KR QG NVLHPMGWDAFGLPAEQYA+DTGN PAEFT +NI  F+ QI++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVNTTDPNYYKWTQWIFLKLFEKGLAYVDEVPVNWCPALGTVLANEEII-DGKSERGGHP  181
            EVNTTDPNYYKWTQWIF KL+EKGLAY  EVPVNW   LGT +ANEE++ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRPMRQWMLKITAYGdrlledldeldWPESLKDMQRNWIGRSEGAEVHFNIDGTDEKF  241
            V R+PMRQWMLKITAY++RLLEDL+E+DWPES+KDMQRNWIG+S GA+V F++ +TD  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  TVFTTRPDTLFGASYCVLAPEHALVADITTAEQKEAVEAYINSVKMKSDLERTELAKEKT  301
            TVFTTRPDTLFGA+Y VLAPEHALV  ITT++Q EAV  Y     +KSDL RT+LAKEKT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAVNPVNGEKLPIWIADYVLATYGTGAVMAVPAHDERDYEFASTFNLPMKEVVK  361
            GV TG+YA+NPVNG  +P+WIADYVLA+YGTGA+MAVPAHDERD EFA  FNL +  V+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGDITKEAYTGDGEHVNSAFLDGLNKEEAIAKMIEWLEVTSAGNQKVTYRLRDWLFSRQR  421
            GG++   A+T DG H+NS FLDGL+K  AIAKM+EWLE  + GN++VTYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPVIHWEDGTMTAVKEEELPLVLPKTDNIRPSGTGESPLANIDEWVNVVDPETGK  481
            YWGEPIP+IHWEDGT TAV E ELPLVLP T +IRPSGTGESPLAN+ +W++V   E G 
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT-REDGV  482

Query  482  KGRRETNTMPQWAGSCWYYLRYIDPNNSEALVDPEKVKQWLPVDIYIGGAEHAVLHLLYA  541
            KGRRETNTMPQWAGS WYYLRYIDP+N+E L D E +KQWLPVDIY+GGAEHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKVLYDIGVVPTKEPFQQLFNQGMILG------------------------------  571
            RFWHKVLYD+GVVPTKEPFQ+LFNQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---ENNEKMSKSKGNVVNPDDIVASHGADTLRLYEMFMGPLDASIAWSENGLDGARRFLD  628
               +   KMSKS  NVVNPDD+V   GADTLR+YEMFMGPLDASIAWSE+GL+G+R+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RVWRLFVQDNGELSEKITDAPNKELEKAYHQTVKKVTEDYAELRFNTAISQMMVFINDAY  688
            RV RL+       +  IT+  +  L+K Y++TVK VTE+  +++FNTAI+Q+MVF+N A 
Sbjct  663  RVYRLIT------TKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  689  KAETLPKEYVEGFVKMIAPVAPHIGEELWSKL-GYNETITYASWPTFDESKLVEDEVEIV  747
            K + L  +Y  GFV++IAP APH+GEELW  L +  E+I+Y +WP++DESKLVE++VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  748  VQVMGKVRAKLTMSKDASKEEMEQLAL--EAIKDQIEGKTVRKVIVVPGKLVNVVAN  802
            VQ+ GKV+AKL ++KD S+EE++++AL  E ++ +I GK + KVI VP KLVN+V +
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

211) leuS in NC_014335


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  934 bits (3540),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 559/837 (67%), Positives = 668/837 (80%), Gaps = 44/837 (5%)

Query  3    FNHQEIEKKWQGYWEENKTFRTPDETEKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  62
            ++H  IE KWQ++W +N TF+T  ++ KPKFYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMKRMQGYNVLHPMGWDAFGLPAEQYALDTGNSPAEFTEHNINTFRNQIKSLGFSYDWDR  122
            R KR QG NVLHPMGWDAFGLPAEQYA+DTGN PAEFT +NI  F+ QI++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVNTTDPNYYKWTQWIFLKLFEKGLAYVDEVPVNWCPALGTVLANEEII-DGKSERGGHP  181
            EVNTTDPNYYKWTQWIF KL+EKGLAY  EVPVNW   LGT +ANEE++ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRPMRQWMLKITAYGdrlledldeldWPESLKDMQRNWIGRSEGAEVHFNIDGTDEKF  241
            V R+PMRQWMLKITAY++RLLEDL+E+DWPES+KDMQRNWIG+S GA+V F++ +TD  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  TVFTTRPDTLFGASYCVLAPEHALVADITTADQKEAVEAYINSVKMKSDLERTELAKEKT  301
            TVFTTRPDTLFGA+Y VLAPEHALV  ITT+DQ EAV  Y     +KSDL RT+LAKEKT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAVNPVNGEKLPIWIADYVLATYGTGAVMAVPAHDERDYEFASTFNLPMKEVVK  361
            GV TG+YA+NPVNG  +P+WIADYVLA+YGTGA+MAVPAHDERD EFA  FNL +  V+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGDITKEAYTGDGAHVNSAFLDGLNKEEAIAKMIEWLEVTSAGNQKVTYRLRDWLFSRQR  421
            GG++   A+T DG H+NS FLDGL+K  AIAKM+EWLE  + GN++VTYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPVIHWEDGTMTAVKEEELPLVLPKTENIRPSGTGESPLANIDEWVNVVDPETGK  481
            YWGEPIP+IHWEDGT TAV E ELPLVLP T +IRPSGTGESPLAN+ +W++V   E G 
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT-REDGV  482

Query  482  KGRRETNTMPQWAGSCWYYLRYIDPNNSEALVDPEKVKQWLPVDIYIGGAEHAVLHLLYA  541
            KGRRETNTMPQWAGS WYYLRYIDP+N+E L D E +KQWLPVDIY+GGAEHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKVLYDIGVVPTKEPFQQLFNQGMILG------------------------------  571
            RFWHKVLYD+GVVPTKEPFQ+LFNQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---ENNEKMSKSKGNVVNPDDIVASHGADTLRLYEMFMGPLDASIAWSENGLDGARRFLD  628
               +   KMSKS  NVVNPDD+V   GADTLR+YEMFMGPLDASIAWSE+GL+G+R+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RVWRLFVQDNGELSEKITDAPNKDLEKPYHQTVKKVTEDYAELRFNTAISQMMVFINDAY  688
            RV RL+       +  IT+  +  L+K Y++TVK VTE+  +++FNTAI+Q+MVF+N A 
Sbjct  663  RVYRLIT------TKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  689  KAETLPKEYVEGFVKMIAPVAPHIGEELWSKL-GYNETITYASWPTFDESKLVEDEVEIV  747
            K + L  +Y  GFV++IAP APH+GEELW  L +  E+I+Y +WP++DESKLVE++VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  748  VQVMGKVRAKLTMSKDASKDEMEKLAL--EAIQDQIEGKTVRKVIVVPGKLVNVVAN  802
            VQ+ GKV+AKL ++KD S++E++ +AL  E +Q +I GK + KVI VP KLVN+V +
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

212) BCN_4647 in NC_016771


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  934 bits (3540),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 558/837 (67%), Positives = 669/837 (80%), Gaps = 44/837 (5%)

Query  3    FNHQEIEKKWQGYWEENKTFRTPDETEKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  62
            ++H  IE KWQ++W +N TF+T  ++ KPKFYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMKRMQGYNVLHPMGWDAFGLPAEQYALDTGNSPAEFTEHNINTFRNQIKSLGFSYDWDR  122
            R KR QG NVLHPMGWDAFGLPAEQYA+DTGN PAEFT +NI  F+ QI++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVNTTDPNYYKWTQWIFLKLFEKGLAYVDEVPVNWCPALGTVLANEEII-DGKSERGGHP  181
            EVNTTDPNYYKWTQWIF KL+EKGLAY  EVPVNW   LGT +ANEE++ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRPMRQWMLKITAYGdrlledldeldWPESLKDMQRNWIGRSEGAEVHFNIDGTDEKF  241
            V R+PMRQWMLKITAY++RLLEDL+E+DWPES+KDMQRNWIG+S GA+V F++ +TD  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  TVFTTRPDTLFGASYCVLAPEHALVADITTAEQKEAVEAYINSVKMKSDLERTELAKEKT  301
            TVFTTRPDTLFGA+Y VLAPEHALV  ITT++Q EAV  Y     +KSDL RT+LAKEKT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAVNPVNGEKLPIWIADYVLATYGTGAVMAVPAHDERDYEFASTFNLPMKEVVK  361
            GV TG+YA+NPVNG  +P+WIADYVLA+YGTGA+MAVPAHDERD EFA  FNL +  V+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGDITKEAYTGDGEHVNSAFLDGLNKEEAIAKMIEWLEVTSAGNQKVTYRLRDWLFSRQR  421
            GG++   A+T DG H+NS FLDGL+K  AIAKM+EWLE  + GN++VTYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPVIHWEDGTMTAVKEEELPLVLPKTDNIRPSGTGESPLANIDEWVNVVDPETGK  481
            YWGEPIP+IHWEDGT TAV E ELPLVLP T +IRPSGTGESPLAN+ +W++V   E G 
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT-REDGV  482

Query  482  KGRRETNTMPQWAGSCWYYLRYIDPNNSEALVDPEKVKQWLPVDIYIGGAEHAVLHLLYA  541
            KGRRETNTMPQWAGS WYYLRYIDP+N+E L D E +KQWLPVDIY+GGAEHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKVLYDIGVVPTKEPFQQLFNQGMILG------------------------------  571
            RFWHKVLYD+GVVPTKEPFQ+LFNQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---ENNEKMSKSKGNVVNPDDIVASHGADTLRLYEMFMGPLDASIAWSENGLDGARRFLD  628
               +   KMSKS  NVVNPDD+V   GADTLR+YEMFMGPLDASIAWSE+GL+G+R+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RVWRLFVQDNGELSEKITDAPNKELEKAYHQTVKKVTEDYAELRFNTAISQMMVFINDAY  688
            RV RL+       +  IT+  +  L+K Y++TVK VTE+  +++FNTAI+Q+MVF+N A 
Sbjct  663  RVYRLIT------TKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  689  KAETLPKEYVEGFVKMIAPVAPHIGEELWSKL-GYNETITYASWPTFDESKLVEDEVEIV  747
            K + L  +Y  GFV++IAP APH+GEELW  L +  E+I+Y +WP++DESKLVE++VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  748  VQVMGKVRAKLTMSKDASKEEMEQLAL--EAIKDQIEGKTVRKVIVVPGKLVNVVAN  802
            VQ+ GKV+AKL ++KD S+EE++++AL  E ++ +I GK + KVI VP KLVN+V +
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

213) leuS in NC_011969


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  934 bits (3540),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 558/837 (67%), Positives = 669/837 (80%), Gaps = 44/837 (5%)

Query  3    FNHQEIEKKWQGYWEENKTFRTPDETEKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  62
            ++H  IE KWQ++W +N TF+T  ++ KPKFYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMKRMQGYNVLHPMGWDAFGLPAEQYALDTGNSPAEFTEHNINTFRNQIKSLGFSYDWDR  122
            R KR QG NVLHPMGWDAFGLPAEQYA+DTGN PAEFT +NI  F+ QI++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVNTTDPNYYKWTQWIFLKLFEKGLAYVDEVPVNWCPALGTVLANEEII-DGKSERGGHP  181
            EVNTTDPNYYKWTQWIF KL+EKGLAY  EVPVNW   LGT +ANEE++ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRPMRQWMLKITAYGdrlledldeldWPESLKDMQRNWIGRSEGAEVHFNIDGTDEKF  241
            V R+PMRQWMLKITAY++RLLEDL+E+DWPES+KDMQRNWIG+S GA+V F++ +TD  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  TVFTTRPDTLFGASYCVLAPEHALVADITTAEQKEAVEAYINSVKMKSDLERTELAKEKT  301
            TVFTTRPDTLFGA+Y VLAPEHALV  ITT++Q EAV  Y     +KSDL RT+LAKEKT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAVNPVNGEKLPIWIADYVLATYGTGAVMAVPAHDERDYEFASTFNLPMKEVVK  361
            GV TG+YA+NPVNG  +P+WIADYVLA+YGTGA+MAVPAHDERD EFA  FNL +  V+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGDITKEAYTGDGEHVNSAFLDGLNKEEAIAKMIEWLEVTSAGNQKVTYRLRDWLFSRQR  421
            GG++   A+T DG H+NS FLDGL+K  AIAKM+EWLE  + GN++VTYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPVIHWEDGTMTAVKEEELPLVLPKTDNIRPSGTGESPLANIDEWVNVVDPETGK  481
            YWGEPIP+IHWEDGT TAV E ELPLVLP T +IRPSGTGESPLAN+ +W++V   E G 
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT-REDGV  482

Query  482  KGRRETNTMPQWAGSCWYYLRYIDPNNSEALVDPEKVKQWLPVDIYIGGAEHAVLHLLYA  541
            KGRRETNTMPQWAGS WYYLRYIDP+N+E L D E +KQWLPVDIY+GGAEHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKVLYDIGVVPTKEPFQQLFNQGMILG------------------------------  571
            RFWHKVLYD+GVVPTKEPFQ+LFNQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---ENNEKMSKSKGNVVNPDDIVASHGADTLRLYEMFMGPLDASIAWSENGLDGARRFLD  628
               +   KMSKS  NVVNPDD+V   GADTLR+YEMFMGPLDASIAWSE+GL+G+R+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RVWRLFVQDNGELSEKITDAPNKELEKAYHQTVKKVTEDYAELRFNTAISQMMVFINDAY  688
            RV RL+       +  IT+  +  L+K Y++TVK VTE+  +++FNTAI+Q+MVF+N A 
Sbjct  663  RVYRLIT------TKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  689  KAETLPKEYVEGFVKMIAPVAPHIGEELWSKL-GYNETITYASWPTFDESKLVEDEVEIV  747
            K + L  +Y  GFV++IAP APH+GEELW  L +  E+I+Y +WP++DESKLVE++VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  748  VQVMGKVRAKLTMSKDASKEEMEQLAL--EAIKDQIEGKTVRKVIVVPGKLVNVVAN  802
            VQ+ GKV+AKL ++KD S+EE++++AL  E ++ +I GK + KVI VP KLVN+V +
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

214) leuS in NC_018500


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  934 bits (3537),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 559/837 (67%), Positives = 667/837 (80%), Gaps = 44/837 (5%)

Query  3    FNHQDIEKKWQGYWEENKTFRTPDETEKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  62
            ++H  IE KWQ++W +N TF+T  ++ KPKFYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMKRMQGYNVLHPMGWDAFGLPAEQYALDTGNSPAEFTEHNINTFRNQIKSLGFSYDWDR  122
            R KR QG NVLHPMGWDAFGLPAEQYA+DTGN PAEFT +NI  F+ QI++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVNTTDPNYYKWTQWIFLKLFEKGLAYVDEVPVNWCPALGTVLANEEII-DGKSERGGHP  181
            EVNTTDPNYYKWTQWIF KL+EKGLAY  EVPVNW   LGT +ANEE++ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRPMRQWMLKITAYGdrlledldeldWPESLKDMQRNWIGRSEGAEVHFNIDGTDEKF  241
            V R+PMRQWMLKITAY++RLLEDL+E+DWPES+KDMQRNWIG+S GA+V F++ +TD  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  TVFTTRPDTLFGATYCVLAPEHALVAEITTAEQKEAVEAYINAVKMKSDLERTELAKEKT  301
            TVFTTRPDTLFGATY VLAPEHALV  ITT++Q EAV  Y     +KSDL RT+LAKEKT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAVNPVNGEKLPIWIADYVLATYGTGAVMAVPAHDERDYEFASVFNLPMKEVVK  361
            GV TG+YA+NPVNG  +P+WIADYVLA+YGTGA+MAVPAHDERD EFA  FNL +  V+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGDITKEVYTGDGAHVNSAFLDGLNKEEAIAKMIEWLEVTSAGNQKVTYRLRDWLFSRQR  421
            GG++    +T DG H+NS FLDGL+K  AIAKM+EWLE  + GN++VTYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPVIHWEDGTMTAVKEEELPLVLPKTENIRPSGTGESPLANIDEWVNVVDPETGK  481
            YWGEPIP+IHWEDGT TAV E ELPLVLP T +IRPSGTGESPLAN+ +W++V   E G 
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT-REDGV  482

Query  482  KGRRETNTMPQWAGSCWYYLRYIDPNNSEALVDPEKVKQWLPVDIYIGGAEHAVLHLLYA  541
            KGRRETNTMPQWAGS WYYLRYIDP+N+E L D E +KQWLPVDIY+GGAEHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKVLYDIGVVPTKEPFQQLFNQGMILG------------------------------  571
            RFWHKVLYD+GVVPTKEPFQ+LFNQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---ENNEKMSKSKGNVVNPDDIVASHGADTLRLYEMFMGPLDASIAWSENGLDGARRFLD  628
               +   KMSKS  NVVNPDD+V   GADTLR+YEMFMGPLDASIAWSE+GL+G+R+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RVWRLFVQDNGELSEKITDAPNKELEKAYHQTVKKVTEDYAELRFNTAISQMMVFINDAY  688
            RV RL+       +  IT+  +  L+K Y++TVK VTE+  +++FNTAI+Q+MVF+N A 
Sbjct  663  RVYRLIT------TKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  689  KAETLPKEYVEGFVKMIAPVAPHIGEELWSKL-GYNETITYASWPIFDESKLVEDEVEIV  747
            K + L  +Y  GFV++IAP APH+GEELW  L +  E+I+Y +WP +DESKLVE++VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  748  VQVMGKVRAKLTMSKDASKEEMEQLAL--EAIQDQIEGKTVRKVIVVPGKLVNVVAN  802
            VQ+ GKV+AKL ++KD S+EE++++AL  E +Q +I GK + KVI VP KLVN+V +
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

215) leuS in NC_018508


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  934 bits (3537),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 559/837 (67%), Positives = 667/837 (80%), Gaps = 44/837 (5%)

Query  3    FNHQDIEKKWQGYWEENKTFRTPDETEKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  62
            ++H  IE KWQ++W +N TF+T  ++ KPKFYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMKRMQGYNVLHPMGWDAFGLPAEQYALDTGNSPAEFTEHNINTFRNQIKSLGFSYDWDR  122
            R KR QG NVLHPMGWDAFGLPAEQYA+DTGN PAEFT +NI  F+ QI++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVNTTDPNYYKWTQWIFLKLFEKGLAYVDEVPVNWCPALGTVLANEEII-DGKSERGGHP  181
            EVNTTDPNYYKWTQWIF KL+EKGLAY  EVPVNW   LGT +ANEE++ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRPMRQWMLKITAYGdrlledldeldWPESLKDMQRNWIGRSEGAEVHFNIDGTDEKF  241
            V R+PMRQWMLKITAY++RLLEDL+E+DWPES+KDMQRNWIG+S GA+V F++ +TD  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  TVFTTRPDTLFGATYCVLAPEHALVAEITTAEQKEAVEAYINAVKMKSDLERTELAKEKT  301
            TVFTTRPDTLFGATY VLAPEHALV  ITT++Q EAV  Y     +KSDL RT+LAKEKT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAVNPVNGEKLPIWIADYVLATYGTGAVMAVPAHDERDYEFASVFNLPMKEVVK  361
            GV TG+YA+NPVNG  +P+WIADYVLA+YGTGA+MAVPAHDERD EFA  FNL +  V+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGDITKEVYTGDGAHVNSAFLDGLNKEEAIAKMIEWLEVTSAGNQKVTYRLRDWLFSRQR  421
            GG++    +T DG H+NS FLDGL+K  AIAKM+EWLE  + GN++VTYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPVIHWEDGTMTAVKEEELPLVLPKTENIRPSGTGESPLANIDEWVNVVDPETGK  481
            YWGEPIP+IHWEDGT TAV E ELPLVLP T +IRPSGTGESPLAN+ +W++V   E G 
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT-REDGV  482

Query  482  KGRRETNTMPQWAGSCWYYLRYIDPNNSEALVDPEKVKQWLPVDIYIGGAEHAVLHLLYA  541
            KGRRETNTMPQWAGS WYYLRYIDP+N+E L D E +KQWLPVDIY+GGAEHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKVLYDIGVVPTKEPFQQLFNQGMILG------------------------------  571
            RFWHKVLYD+GVVPTKEPFQ+LFNQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---ENNEKMSKSKGNVVNPDDIVASHGADTLRLYEMFMGPLDASIAWSENGLDGARRFLD  628
               +   KMSKS  NVVNPDD+V   GADTLR+YEMFMGPLDASIAWSE+GL+G+R+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RVWRLFVQDNGELSEKITDAPNKELEKAYHQTVKKVTEDYAELRFNTAISQMMVFINDAY  688
            RV RL+       +  IT+  +  L+K Y++TVK VTE+  +++FNTAI+Q+MVF+N A 
Sbjct  663  RVYRLIT------TKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  689  KAETLPKEYVEGFVKMIAPVAPHIGEELWSKL-GYNETITYASWPIFDESKLVEDEVEIV  747
            K + L  +Y  GFV++IAP APH+GEELW  L +  E+I+Y +WP +DESKLVE++VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  748  VQVMGKVRAKLTMSKDASKEEMEQLAL--EAIQDQIEGKTVRKVIVVPGKLVNVVAN  802
            VQ+ GKV+AKL ++KD S+EE++++AL  E +Q +I GK + KVI VP KLVN+V +
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

216) leuS in NC_011772


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  933 bits (3536),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 558/837 (67%), Positives = 667/837 (80%), Gaps = 44/837 (5%)

Query  3    FNHQDIEKKWQGYWEENKTFRTPDETEKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  62
            ++H  IE KWQ++W +N TF+T  ++ KPKFYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMKRMQGYKVLHPMGWDAFGLPAEQYALDTGNSPAEFTEHNINTFRNQIKSLGFSYDWDR  122
            R KR QG +VLHPMGWDAFGLPAEQYA+DTGN PAEFT +NI  F+ QI++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVNTTDPNYYKWTQWIFLKLFEKGLAYVDEVPVNWCPALGTVLANEEII-DGKSERGGHP  181
            EVNTTDPNYYKWTQWIF KL+EKGLAY  EVPVNW   LGT +ANEE++ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRPMRQWMLKITAYGdrlledldeldWPESLKDMQRNWIGRSEGAEVHFNIDGTDEKF  241
            V R+PMRQWMLKITAY++RLLEDL+E+DWPES+KDMQRNWIG+S GA+V F++ +TD  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  TVFTTRPDTLFGATYCVLAPEHALVAEITTAEQKEAVEAYINAVKMKSDLERTELAKEKT  301
            TVFTTRPDTLFGATY VLAPEHALV  ITT++Q EAV  Y     +KSDL RT+LAKEKT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAVNPVNGEKLPIWIADYVLATYGTGAVMAVPAHDERDYEFASVFNLPMKEVVK  361
            GV TG+YA+NPVNG  +P+WIADYVLA+YGTGA+MAVPAHDERD EFA  FNL +  V+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGDITKEVYTGDGAHVNSAFLDGLNKEEAIAKMIEWLEVTSAGNQKVTYRLRDWLFSRQR  421
            GG++    +T DG H+NS FLDGL+K  AIAKM+EWLE  + GN++VTYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPVIHWEDGTMTAVKEEELPLVLPKTENIRPSGTGESPLANIDEWVNVVDPETGK  481
            YWGEPIP+IHWEDGT TAV E ELPLVLP T +IRPSGTGESPLAN+ +W++V   E G 
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT-REDGV  482

Query  482  KGRRETNTMPQWAGSCWYYLRYIDPNNSEALVDPEKVKQWLPVDIYIGGAEHAVLHLLYA  541
            KGRRETNTMPQWAGS WYYLRYIDP+N+E L D E +KQWLPVDIY+GGAEHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKVLYDIGVVPTKEPFQQLFNQGMILG------------------------------  571
            RFWHKVLYD+GVVPTKEPFQ+LFNQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---ENNEKMSKSKGNVVNPDDIVASHGADTLRLYEMFMGPLDASIAWSENGLDGARRFLD  628
               +   KMSKS  NVVNPDD+V   GADTLR+YEMFMGPLDASIAWSE+GL+G+R+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RVWRLFVQDNGELSEKITDAPNKELEKAYHQTVKKVTEDYAELRFNTAISQMMVFINDAY  688
            RV RL+       +  IT+  +  L+K Y++TVK VTE+  +++FNTAI+Q+MVF+N A 
Sbjct  663  RVYRLIT------TKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  689  KAETLPKEYVEGFVKMIAPVAPHIGEELWSKL-GYNETITYASWPIFDESKLVEDEVEIV  747
            K + L  +Y  GFV++IAP APH+GEELW  L +  E+I+Y +WP +DESKLVE++VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  748  VQVMGKVRAKLTMSKDASKEEMEQLAL--EAIQDQIEGKTVRKVIVVPGKLVNVVAN  802
            VQ+ GKV+AKL ++KD S+EE++++AL  E +Q +I GK + KVI VP KLVN+V +
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

217) leuS in NC_017200


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  933 bits (3534),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 558/837 (67%), Positives = 668/837 (80%), Gaps = 44/837 (5%)

Query  3    FNHQEIEKKWQGYWEENKTFRTPDETEKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  62
            ++H  IE KWQ++W +N TF+T  ++ KPKFYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMKRMQGYNVLHPMGWDAFGLPAEQYALDTGNSPAEFTEHNINTFRNQIKSLGFSYDWDR  122
            R KR QG NVLHPMGWDAFGLPAEQYA+DTGN PAEFT +NI  F+ QI++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVNTTDPNYYKWTQWIFLKLFEKGLAYVDEVPVNWCPALGTVLANEEII-DGKSERGGHP  181
            EVNTTDPNYYKWTQWIF KL+EKGLAY  EVPVNW   LGT +ANEE++ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRPMRQWMLKITAYGdrlledldeldWPESLKDMQRNWIGRSEGAEVHFNIDGTDEKF  241
            V R+PMRQWMLKITAY++RLLEDL+E+DWPES+KDMQRNWIG+S GA+V F++ +TD  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  TVFTTRPDTLFGATYCVLAPEHALVAEITTAEQKEAVEAYINAVKMKSDLERTELAKEKT  301
            TVFTTRPDTLFGATY VLAPEHALV  ITT++Q EAV  Y     +KSDL RT+LAKEKT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAVNPVNGEKLPIWIADYVLATYGTGAVMAVPAHDERDYEFASVFNLPMKEVVK  361
            GV TG+YA+NPVNG  +P+WIADYVLA+YGTGA+MAVPAHDERD EFA  FNL +  V+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGDITKEVYTGDGPHVNSAFLDGLNKEEAIAKMIEWLEVTSAGNQKVTYRLRDWLFSRQR  421
            GG++    +T DG H+NS FLDGL+K  AIAKM+EWLE  + GN++VTYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPVIHWEDGTMTAVKEEELPLVLPKTDNIRPSGTGESPLANIEEWVNVVDPETGK  481
            YWGEPIP+IHWEDGT TAV E ELPLVLP T +IRPSGTGESPLAN+ +W++V   E G 
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT-REDGV  482

Query  482  KGRRETNTMPQWAGSCWYYLRYIDPNNSEALVDPEKVKQWLPVDIYIGGAEHAVLHLLYA  541
            KGRRETNTMPQWAGS WYYLRYIDP+N+E L D E +KQWLPVDIY+GGAEHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKVLYDIGVVPTKEPFQQLFNQGMILG------------------------------  571
            RFWHKVLYD+GVVPTKEPFQ+LFNQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---ENNEKMSKSKGNVVNPDDIVASHGADTLRLYEMFMGPLDASIAWSENGLDGARRFLD  628
               +   KMSKS  NVVNPDD+V   GADTLR+YEMFMGPLDASIAWSE+GL+G+R+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RVWRLFVQDNGELSEKITDAPNKELEKAYHQTVKKVTEDYAELRFNTAISQMMVFINDAY  688
            RV RL+       +  IT+  +  L+K Y++TVK VTE+  +++FNTAI+Q+MVF+N A 
Sbjct  663  RVYRLIT------TKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  689  KAETLPKEYVEGFVKMIAPVAPHIGEELWSKL-GYNETITYASWPTFDESKLVEDEVEIV  747
            K + L  +Y  GFV++IAP APH+GEELW  L +  E+I+Y +WP++DESKLVE++VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  748  VQVMGKVRAKLTMSKDASKEEMEQLAL--EAIKDQIEGKTVRKVIVVPGKLVNVVAN  802
            VQ+ GKV+AKL ++KD S+EE++++AL  E ++ +I GK + KVI VP KLVN+V +
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

218) MC28_4019 in NC_018693


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  931 bits (3528),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 559/837 (67%), Positives = 666/837 (80%), Gaps = 44/837 (5%)

Query  3    FNHQEIEKKWQGYWEENKTFRTPDETEKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  62
            ++H  IE KWQ++W +N TF+T  ++ KPKFYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMKRMQGYNVLHPMGWDAFGLPAEQYALDTGNSPAEFTELNINTFRNQIKALGFSYDWDR  122
            R KR QG NVLHPMGWDAFGLPAEQYA+DTGN PAEFT  NI  F+ QI+ALGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVNTTDPNYYKWTQWIFLKLFEKGLAYVDEVPVNWCPALGTVLANEEII-DGKSERGGHP  181
            EVNTTDPNYYKWTQWIF KL+EKGLAY  EVPVNW   LGT +ANEE++ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRPMRQWMLKITAYGdrlledldeldWPESLKDMQRNWIGRSEGAEVHFNIDGTDEKF  241
            V R+PMRQWMLKITAY++RLLEDL+E+DWPES+KDMQRNWIG+S GA+V F++ +TD  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  TVFTTRPDTLFGATYCVLAPEHALVAEITTAEQKEAVEAYINSVKMKSDLERTELAKEKT  301
            TVFTTRPDTLFGATY VLAPEHALV  ITT++Q EAV  Y     +KSDL RT+LAKEKT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAVNPVNGEKLPIWIADYVLATYGTGAVMAVPAHDERDYEFASVFNLPMKEVVK  361
            GV TG+YA+NPVNG  +P+WIADYVLA+YGTGA+MAVPAHDERD EFA  FNL +  V+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGDITKEVYTGDGAHVNSAFLDGLNKEEAIAKMIEWLEVTSAGNQKVTYRLRDWLFSRQR  421
            GG++    +T DG H+NS FLDGL+K  AIAKM+EWLE  + GN++VTYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPVIHWEDGTMTAVKEEELPLVLPKTENIRPSGTGESPLANIEEWVNVVDPETGK  481
            YWGEPIP+IHWEDGT TAV E ELPLVLP T +IRPSGTGESPLAN+ +W++V   E G 
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT-REDGV  482

Query  482  KGRRETNTMPQWAGSCWYYLRYMDPNNNEALVDPEKVKQWLPVDIYIGGAEHAVLHLLYA  541
            KGRRETNTMPQWAGS WYYLRY+DP+N E L D E +KQWLPVDIY+GGAEHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKVLYDIGVVPTKEPFQQLFNQGMILG------------------------------  571
            RFWHKVLYD+GVVPTKEPFQ+LFNQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---ENNEKMSKSKGNVVNPDDIVASHGADTLRLYEMFMGPLDASIAWSENGLDGARRFLD  628
               +   KMSKS  NVVNPDD+V   GADTLR+YEMFMGPLDASIAWSE+GL+G+R+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RVWRLFVQDNGELSEKITDAPNQELEKAYHQTVKKVTEDYAELRFNTAISQMMVFINDAY  688
            RV RL+       +  IT+  +  L+K Y++TVK VTE+  +++FNTAI+Q+MVF+N A 
Sbjct  663  RVYRLIT------TKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  689  KANTLPKEYVEGFVKMIAPVAPHIGEELWSKL-GYNETITYASWPTFDESKLVEDEVEIV  747
            K + L  +Y  GFV++IAP APH+GEELW  L +  E+I+Y +WP++DESKLVE++VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  748  VQIMGKVRAKLTMSKDASKEEMEQLAL--EAIKEQIEGKTVRKVIVVPGKLVNVVAN  802
            VQI GKV+AKL ++KD S+EE++++AL  E ++ +I GK + KVI VP KLVN+V +
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

219) MY9_3033 in NC_017743


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  930 bits (3523),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 560/837 (67%), Positives = 668/837 (80%), Gaps = 42/837 (5%)

Query  3    FQHKEIEKKWQTYWLENKTFATLDNNEKQKFYALDMFPYPSGAGLHVGHPEGYTATDILS  62
            ++H  IE KWQ++W +N TF T  +  K KFYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMKRMQGYDVLHPMGWDAFGLPAEQYALDTGNDPAVFTKQNIDNFRRQIQALGFSYDWDR  122
            R KR QG +VLHPMGWDAFGLPAEQYA+DTGNDPA FT +NI NF+RQI+ALGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EINTTDPEYYKWTQWIFLKLYEKGLAYVDEVPVNWCPALGTVLANEEVI-DGKSERGGHP  181
            E+NTTDP+YYKWTQWIF KLYEKGLAY  EVPVNW   LGT +ANEEV+ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRPMKQWMLKITAYAdrlledleeldWPESIKDMQRNWIGRSEGAHVHFAIDGHDESF  241
            V R+PM+QWMLKITAYA+RLLEDLEE+DWPESIKDMQRNWIG+S GA+V F + + D  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  TVFTTRPDTLFGATYTVLAPEHALVENITTAEQKEAVEAYIKEIQSKSDLERTDLAKTKT  301
            TVFTTRPDTLFGATY+VLAPEHALV+ ITT++Q EAV  Y ++   KSDL RTDLAK KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAINPVNGEKLPIWIADYVLASYGTGAVMAVPGHDERDFEFANTFGLPVKEVVK  361
            GV TG+YAINPVNG  +P+WIADYVLASYGTGA+MAVP+HDERD EFA+ F L +  V+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGNIEEAAYTGDGEHVNSDFLNGLNKQEAIEKMIAWLEETKNGEKKVTYRLRDWLFSRQR  421
            GGN+EEAA+T DG H+NSDFL+GL+K  AI KM+ WLE    G+ +VTYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPVIHWEDGTSTAVPEEELPLILPKTDEIKPSGTGESPLAIIKEWVEVTDPETGK  481
            YWGEPIP+IHWEDGTSTAVPE ELPL+LP T +I+PSGTGESPLA + +W+EVT  E G 
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT-REDGV  482

Query  482  KGRRETNTMPQWAGSCWYFLRYIDPHNPDQLASPEKLEKWLPVDMYIGGAEHAVLHLLYA  541
            KGRRETNTMPQWAGS WY+LRYIDPHN ++LA  E L +WLPVD+Y+GGAEHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKFLYDIGVVPTKEPFQKLYNQGMILG------------------------------  571
            RFWHK LYD+GVVPTKEPFQKL+NQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---ENNEKMSKSKGNVVNPDEIVASHGADTLRLYEMFMGPLDASIAWSESGLDGARRFLD  628
               +   KMSKS  NVVNPD++V   GADTLR+YEMFMGPLDASIAWSE GL+G+R+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RVWRLFVEDSGELNGKIVEGAGETLERVYHETVMKVTDHYEGLRFNTGISQLMVFINEAY  688
            RV RL+          I E  + +L++VY+ETV  VT++ + ++FNT+I+QLMVF+N A 
Sbjct  663  RVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  689  KATELPKEYMEGFVKLLSPVAPHLAEELWEKLGHSG-TIAYEAWPVYDETKLVDDEVEIV  747
            K   L  +Y  GFV+L++P APHL+EELW+ L  SG +I+Y +WP YDE+KLV+++VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  748  VQLNGKVKAKLQVPADATREQLEQLAQADEKVKEQLEGKTIRKIIAVPGKLVNIVAN  804
            VQ++GKVKAKL V+ D +RE+L+++A A+EKV+ ++ GK I K+IAVP KLVNIV +
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

220) leuS in NC_009674


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  928 bits (3516),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 563/837 (68%), Positives = 664/837 (80%), Gaps = 44/837 (5%)

Query  3    FNHQEIEKKWQAYWEENKTFRTPDETDKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  62
            ++H  IE KWQA+W +N TF+T  ++ KPKFYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMKRMQGYNVLHPMGWDAFGLPAEQYALDTGNSPAEFTEKNINTFRNQIKSLGFSYDWDR  122
            R KR QG NVLHPMGWDAFGLPAEQYA+DTGN PAEFT  NI  F+ QI++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVNTTDPNYYKWTQWIFLKLFEKGLAYVDEIPVNWCPALGTVLANEEVI-DGKSERGGHP  181
            EVNTTDPNYYKWTQWIF KL+EKGLAY  E+PVNW   LGT +ANEEV+ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRPMKQWMLKITAYAdrlledldeldWPESLKDMQRNWIGRSEGAEVHFNIDGTDKKF  241
            V R+PM+QWMLKITAYA+RLLEDL+E+DWPES+KDMQRNWIG+S GA+V F++ +TDK F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  TIFTTRPDTLFGATYCVLAPEHALVAEITTEDQKGAVEAYIDVVKSKSDLERTELAKEKT  301
            T+FTTRPDTLFGATY VLAPEHALV  ITT DQ  AV  Y      KSDL RT+LAKEKT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAINPVNGEKLPIWIADYVLASYGTGAVMAVPAHDERDYEFAKTFDLPMKEVVK  361
            GV TG+YAINPVNG  +P+WIADYVLASYGTGA+MAVPAHDERD EFAK F+L +  V+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGDITKEAYTADGEHIDSAFLNGLNKEEAIAKMIEWLEVTGAGNQKVTYRLRDWLFSRQR  421
            GG++   A+T DG HI+S FL+GL+K  AIAKM+EWLE  G GN++VTYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPIIHWEDGTMTAVKEEELPLVLPKTDNIRPSGTGESPLANIDEWVNVVDPETGK  481
            YWGEPIPIIHWEDGT TAV E ELPLVLP T +IRPSGTGESPLAN+ +W++V   E G 
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT-REDGV  482

Query  482  KGRRETNTMPQWAGSCWYYLRYIDPNNNEALVDPEKAKQWLPVDIYIGGAEHAVLHLLYA  541
            KGRRETNTMPQWAGS WYYLRYIDP+N E L D E  KQWLPVDIY+GGAEHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKVLYDIGVVPTKEPFQQLFNQGMILG------------------------------  571
            RFWHKVLYD+GVVPTKEPFQ+LFNQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---ENNEKMSKSKGNVVNPDDIVASHGADTLRLYEMFMGPLDASIAWSENGLDGARRFLD  628
               +   KMSKS  NVVNPDD+V   GADTLR+YEMFMGPLDASIAWSE+GL+G+R+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RVWRLFVQENGELSEKITDAPNKELEKAYHQTVKKVTEDYEELHFNTAISQMMMFINDAY  688
            RV RL+       +  IT+  +  L+K Y++TVK VTE+ +++ FNTAI+Q+M+F+N A 
Sbjct  663  RVYRLIT------TKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  689  KAETLPKEYVEGFVKLLAPVAPHIAEELWSKL-GYNETITYASWPTFDESKLVEDEVEIV  747
            K + L  +Y  GFV+L+AP APH++EELW  L +  E+I+Y +WP++DESKLVE++VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  748  VQVMGKVRAKLKMKKDASKEEMEQLAL--EEVKEQIEGKTVRKVIVVPGKLVNIVAN  802
            VQ+ GKV+AKL + KD S+EE++++AL  E V+ +I GK + KVI VP KLVNIV +
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

221) leuS in NC_016047


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  927 bits (3513),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 558/837 (67%), Positives = 668/837 (80%), Gaps = 42/837 (5%)

Query  3    FQHKEIEKKWQTYWLENKTFATLDNNEKQKFYALDMFPYPSGAGLHVGHPEGYTATDILS  62
            ++H  IE KWQ++W +N TF T  +  K KFYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMKRMQGYDVLHPMGWDAFGLPAEQYALDTGNDPAVFTKQNIDNFRRQIQSLGFSYDWDR  122
            R KR QG +VLHPMGWDAFGLPAEQYA+DTGNDPA FT +NI NF+RQI++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EINTTDPEYYKWTQWIFLKLYEKGLAYVDEVPVNWCPALGTVLANEEVI-DGKSERGGHP  181
            E+NTTDP+YYKWTQWIF KLYEKGLAY  EVPVNW   LGT +ANEEV+ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRPMKQWMLKITAYAdrlledleeldWPESIKDMQRNWIGRSEGAHVHFTVDGHAESF  241
            V R+PM+QWMLKITAYA+RLLEDLEE+DWPESIKDMQRNWIG+S GA+V F V +    F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  TVFTTRPDTLFGATYTVLAPEHALVENITTAEQKEAVEAYIKEIQSKSDLERTDLAKTKT  301
            TVFTTRPDTLFGATY+VLAPEHALV+ ITT++Q EAV  Y ++   KSDL RTDLAK KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAINPVNGEKLPIWIADYVLASYGTGAVMAVPGHDERDFEFAKTFGLPVKEIVK  361
            GV TG+YAINPVNG  +P+WIADYVLASYGTGA+MAVP+HDERD EFAK F L +  ++ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGNVEEAAYTGDGEHVNSDFLNGLNKQEAIEKVIAWLEETKNGEKKVTYRLRDWLFSRQR  421
            GGNVEEAA+T DG H+NSDFL+GL+K  AI K++ WLE    G+ +VTYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPVIHWEDGTSTAVPEEELPLILPKTDEIKPSGTGESPLANIKDWVEVTDPETGK  481
            YWGEPIP+IHWEDGTSTAVPE ELPL+LP T +I+PSGTGESPLAN+ DW+EVT  E G 
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT-REDGV  482

Query  482  KGRRETNTMPQWAGSCWYFLRYIDPRNPNQLASPEKLEKWLPVDMYIGGAEHAVLHLLYA  541
            KGRRETNTMPQWAGS WY+LRYIDP+N ++LA  E L +WLPVD+Y+GGAEHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKFLYDIGVVPTKEPFQKLYNQGMILG------------------------------  571
            RFWHK LYD+GVVPTKEPFQKL+NQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---ENNEKMSKSKGNVVNPDEIVASHGADTLRLYEMFMGPLDASIAWSESGLDGARRFLD  628
               +   KMSKS  NVVNPD++V   GADTLR+YEMFMGPLDASIAWSE GL+G+R+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RVWRLFVEDSGELNGKIVEGAGETLERVYHETVMKVTDHYEGLRFNTGISQLMVFINEAY  688
            RV RL+          I E  + +L++VY+ETV  VT++ + ++FNT+I+QLMVF+N A 
Sbjct  663  RVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  689  KATELPKEYMEGFVKLLSPVAPHLAEELWEKLGHSG-TIAYEAWPEYDETKLVDDEVEIV  747
            K   L  +Y  GFV+L++P APHL+EELW+ L  SG +I+Y +WP YDE+KLV+++VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  748  VQLNGKVKAKLQVPADATKEQLEQLAQADEKIKEQLEGKTIRKIIAVPGKLVNIVAN  804
            VQ++GKVKAKL V+ D ++E+L+++A A+EK++ ++ GK I K+IAVP KLVNIV +
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

222) leuS in NC_017138


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  926 bits (3508),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 563/837 (68%), Positives = 669/837 (80%), Gaps = 42/837 (5%)

Query  3    FNHEKIEQKWQKVWEENKTFRTTEDEGKRKFYALDMFPYPSGAGLHVGHPEGYTATDILS  62
            ++H  IE KWQ  W +N TF+T  D +K KFYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMKRMQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTELNINNFRRQIKSLGFSYDWER  122
            R KR QG NVLHPMGWDAFGLPAEQYA+DTGNDPAEFT  NI NF+RQI++LGFSYDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EINTTDPNYYKWTQWIFLQLYKKGLAYVDEVAVNWCPALGTVLANEEVI-DGKSERGGHP  181
            E+NTTDPNYYKWTQWIF +LY KGLAY  EV+VNW   LGT +ANEEV+ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRPMKQWMLKITAYAdrlledldeldWPESIKEMQRNWIGRSEGAHVHFTIDGYDETF  241
            V R+PM+QWMLKITAYA+RLLEDL+E+DWPESIK+MQRNWIG+S GA+V F + + D  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  TVFTTRPDTLFGATYAVLAPEHPFVDKITTAEQKEAVEAYLDQIKSKSDLERTDLAKDKT  301
            TVFTTRPDTLFGATYAVLAPEH++VD ITT++Q EAV  Y  Q   KSDL RTDLAK+KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAINPVNGERMPIWIADYVLMSYGTGAIMAVPAHDERDYEFAVKFELPIKEVVA  361
            GV TG+YAINPVNG  MP+WIADYVL SYGTGAIMAVPAHDERD EFA +F+L I  V+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGDVSKEAYTGDGEHVNSEFLNGLDKEEAISNMIQWLQANEKGEKQVTYRLRDWLFSRQR  421
            GG+V   A+T DG H+NS+FL+GLDK  AI++M++WL+A+  G+ +VTYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPVIHWEDGTTTAVPEDQLPLVLPKTTEIKPSGTGESPLANIDDWVNVVDPETGK  481
            YWGEPIP+IHWEDGT+TAVPE +LPLVLP T +I+PSGTGESPLAN+ DW++V   E G 
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT-REDGV  482

Query  482  KGRRETNTMPQWAGSCWYYLRYIDPTNSEALADADKLKEWLPVDIYIGGAEHAVLHLLYA  541
            KGRRETNTMPQWAGS WYYLRYIDP N+E LAD + LK+WLPVDIY+GGAEHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKFLYDIGVVPTKEPFQKLFNQGMILG------------------------------  571
            RFWHK LYD+GVVPTKEPFQKLFNQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---ENNEKMSKSKGNVVNPDEIVESHGADTLRLYEMFMGPLDASIAWSTKGLDGARRFLD  628
               +   KMSKS  NVVNPD++VE  GADTLR+YEMFMGPLDASIAWS  GL+G+R+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RVWRLLVDDNGELSSKVQESNDTTLERVYHQTVKKVTEDYEGLRFNTGISQLMVFINDAY  688
            RV RL+       +  + E N  +L++VY++TVK VTE+ + ++FNT+I+QLMVF+N A 
Sbjct  663  RVYRLIT------TKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  689  KVDVLPKQYVEGFVKLLAPICPHTTEELWSKL-GHEDTISYEAWPAFDEAKLVDDEVEIV  747
            K D L  +Y  GFV+L+AP+ PH  EELW  L +  ++ISY +WP++DE+KLV+++VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  748  VQINGKVRAKLNVPAEASREELQDIAMANEDVQEFIEGKTVRKVIAVPGKLVNIVAN  804
            VQI+GKV+AKL V+ + SREELQ++A+ANE VQ  I GK + KVIAVP KLVNIV +
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

223) leuS in NC_014479


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  926 bits (3508),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 558/837 (67%), Positives = 668/837 (80%), Gaps = 42/837 (5%)

Query  3    FQHKEIEKKWQTYWLENKTFATLDHNEKQKFYALDMFPYPSGAGLHVGHPEGYTATDILS  62
            ++H  IE KWQ++W +N TF T  +  K KFYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMKRMQGYDVLHPMGWDAFGLPAEQYALDTGNDPAVFTKQNIDNFRRQIQSLGFSYDWDR  122
            R KR QG +VLHPMGWDAFGLPAEQYA+DTGNDPA FT +NI NF+RQI++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EINTTDPEYYKWTQWIFLKLYEKGLAYVDEVPVNWCPALGTVLANEEVI-DGKSERGGHP  181
            E+NTTDP+YYKWTQWIF KLYEKGLAY  EVPVNW   LGT +ANEEV+ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRPMKQWMLKITAYAdrlledleeldWPESIKDMQRNWIGRSEGAHVHFAVDGHAESF  241
            V R+PM+QWMLKITAYA+RLLEDLEE+DWPESIKDMQRNWIG+S GA+V F V +    F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  TVFTTRPDTLFGATYTVLAPEHALVENITTAEQKEAVEAYIKEIQSKSDLERTDLAKTKT  301
            TVFTTRPDTLFGATY+VLAPEHALV+ ITT++Q EAV  Y ++   KSDL RTDLAK KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAINPVNGEKLPIWIADYVLASYGTGAVMAVPGHDERDFEFAKTFGLPVKEVVK  361
            GV TG+YAINPVNG  +P+WIADYVLASYGTGA+MAVP+HDERD EFAK F L +  V+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGNIEEAAYTGDGEHVNSDFLNGLNKQEAIEKVIAWLEETKNGEKKVTYRLRDWLFSRQR  421
            GGN+EEAA+T DG H+NSDFL+GL+K  AI K++ WLE    G+ +VTYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPVIHWEDGTSTAVPEEELPLILPKTDEIKPSGTGESPLANIKDWVEVTDPQTGK  481
            YWGEPIP+IHWEDGTSTAVPE ELPL+LP T +I+PSGTGESPLAN+ DW+EVT  + G 
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT-REDGV  482

Query  482  KGRRETNTMPQWAGSCWYFLRYIDPRNPDQLASPEKLEKWLPVDMYIGGAEHAVLHLLYA  541
            KGRRETNTMPQWAGS WY+LRYIDP+N ++LA  E L +WLPVD+Y+GGAEHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKFLYDIGVVPTKEPFQKLYNQGMILG------------------------------  571
            RFWHK LYD+GVVPTKEPFQKL+NQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---ENNEKMSKSKGNVVNPDEIVASHGADTLRLYEMFMGPLDASIAWSESGLDGARRFLD  628
               +   KMSKS  NVVNPD++V   GADTLR+YEMFMGPLDASIAWSE GL+G+R+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RVWRLFVEDSGELNGKIVEGAGETLERVYHETVMKVTDHYEGLRFNTGISQLMVFINEAY  688
            RV RL+          I E  + +L++VY+ETV  VT++ + ++FNT+I+QLMVF+N A 
Sbjct  663  RVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  689  KATELPKEYMEGFVKLLSPVAPHLAEELWEKLGHSG-TIAYEAWPVYDETKLVDDEVEIV  747
            K   L  +Y  GFV+L++P APHL+EELW+ L  SG +I+Y +WP YDE+KLV+++VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  748  VQLNGKVKAKLQVPADATKEQLEQLAQADEKVKEQLEGKTIRKIIAVPGKLVNIVAN  804
            VQ++GKVKAKL V+ D ++E+L+++A A+EKV+ ++ GK I K+IAVP KLVNIV +
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

224) leuS in NC_012491


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  926 bits (3507),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 551/838 (66%), Positives = 672/838 (81%), Gaps = 43/838 (5%)

Query  3    FSHRNVEKKWQQYWEQNKTFKTSEDEGKKKFYALDMFPYPSGAGLHVGHPEGYTATDILS  62
            + H  +E KWQ +W +N TFKT+ D +K KFYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMKRMQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTEHNINTFRRQIKSLGFSYDWDR  122
            R KR QG NVLHPMGWDAFGLPAEQYA+DTGNDPAEFT +NI  F+RQI++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EINTTDPHYYKWTQWIFTKLYEHGLAYIDEVAVNWCPALGTVLANEEVI-DGKSERGGHP  181
            E+NTTDP+YYKWTQWIFTKLYE GLAY  EV+VNW   LGT +ANEEV+ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRPMKQWVLKITAYaerlladldeldWPESIKEMQRNWIGRSEGAEVTFGIEGHDESF  241
            V R+PM+QW+LKITAYAERLL DL+E+DWPESIK+MQRNWIG+S GA+VTF + + D  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  TVFTTRPDTLYGATYAVLAPEHKLVEQITVPAQKEAVEAYLDQAKRKSDLERTDLAKEKT  301
            TVFTTRPDTL+GATYAVLAPEH LV+ IT + Q EAV  Y  QA  KSDL RTDLAKEKT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAINPVNGERLPIWIADYVLISYGTGSIMAVPAHDERDYEFAKTFDLPIKQVIA  361
            GV TG+YAINPVNG  +P+WIADYVL SYGTG+IMAVPAHDERD EFAK F+L I  V+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGDISKEAYAGDGEHINSGMLDGLNKEQAISKMIEWLEAEGKGNRKVTYRLRDWLFSRQR  421
            GG++   A++ DG HINS+ LDGL+K  AI+KM+EWLEAEG GN +VTYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPILHLEDGTMKVVPESELPIMLPKTKEIKPSGTGESPLANIAEWVNTIDPETGM  481
            YWGEPIPI+H EDGT   VPESELP++LP TK+I+PSGTGESPLAN+++W++ +  E G+
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE-VTREDGV  482

Query  482  KARRETNTMPQWAGSCWYFLRFIDPHNDKALADPDKLKEWLPIDIYIGGAEHAVLHLLYS  541
            K+RRETNTMPQWAGS WY+LR+IDPHN   LAD + LK+WLP+DIY+GGAEHAVLHLLY+
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKFLYDIGVVPTKEPFQKLFNQGMILG------------------------------  571
            RFWHK LYD+GVVPTKEPFQKLFNQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---ENNEKMSKSKGNVVNPDDIIDSHGADTLRMYEMFMGPLDASIAWSTKGLDGARRFLD  628
               +   KMSKS  NVVNPDD+++  GADTLR+YEMFMGPLDASIAWS  GL+G+R+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RVYRLFVGDNGELNEKIVETSNVAGMERVYHQTVKKVTEDYEGLRFNTGISQLMVFVNEA  688
            RVYRL       +  K +   N +++++VY++TVK VTE+ + ++FNT+I+QLMVFVN A
Sbjct  663  RVYRL-------ITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAA  715

Query  689  YKAEVLPKKFMEDFVKMLSPIAPHLGEELWEKL-GHSESVAYAAWPTYDEAKLVEDEVEI  747
             K + L   +  +FV++++P+APHLGEELW+ L + +ES++Y +WP+YDE+KLVE++VEI
Sbjct  716  NKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEI  775

Query  748  VLQINGKNKEKLLIASDSTKEQMEEMAKNNEMINELIEGKTIVKVIAVPGKLVNIVVR  805
            V+QI+GK K KL++A D ++E+++E+A  NE ++  I GK I+KVIAVP KLVNIV++
Sbjct  776  VVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

225) leuS in NC_016052


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  925 bits (3506),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 574/822 (70%), Positives = 680/822 (83%), Gaps = 42/822 (5%)

Query  1    MKTYDHKAIEKRWQNYWEKNNTFVTTEDEQKPKAYIMDMFPYPSGQGLHVGHPEGYTATD  60
            M  YDH AIE +WQ +W  N+TF T  D  KPK Y +DMFPYPSG GLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   ILARMKRSQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTKKNIEVFRKQINSLGFSYD  120
            IL+R KR+QG NVLHPMGWDAFGLPAEQYA+DTGNDPAEFT  NI  F++QIN+LGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WAREINTTDPDYYKWTQWIFTKLYEKGLAYEAEVPVNWVPELGTVIANEEVI-DGKSERG  179
            W RE+NTTDP+YYKWTQWIFTKLYEKGLAYEAEVPVNWV ELGT IANEEV+ DG SERG
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  180  DYDVVRKPMRQWMLKITAYAdrllddledldWPESIKEMQRNWIGRSVGANVQFKIKDTD  239
            +Y VVRKPMRQWMLKITAYA+RLL+DLE++DWPESIK+MQRNWIG+S GANV FK+KDTD
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  240  ETFTVFTTRPDTLFGATYAVFAPELDLVKQITTAKQKETVDQYIAEAAKKSELSRTDLAK  299
              FTVFTTRPDTLFGATYAV+APE  LV  ITT+ Q E+V +Y  +A+ KS+L+RTDLAK
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  300  EKTGVFTGAYAINPVNGNEIPIWIADYVLSSYGTGAIMSVPAHDERDYEFAKKFNLDIVP  359
            EKTGV TG+YAINPVNG+E+P+WIADYVL+SYGTGAIM+VPAHDERD EFAK+FNLDI+P
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  360  VLEGGDIEKEAFTEDGPHINSGFLNGLNKEEAIEKMMAWLEKEGLGQKEVSYRLRDWLFS  419
            VLEGG++E  AFTEDG HINS+FL+GL+K  AI KM+ WLE EG+G+ +V+YRLRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  420  RQRYWGEPIPIIHWEDGTTSALSEDELPLELPKAADIKPSGTGESPLANVTDWVNVTDPV  479
            RQRYWGEPIPIIHWEDGT++A++E ELPL LP + DI+PSGTGESPLANVTDW++VT   
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRE-  479

Query  480  TGKKGHRETNTMPQWAGSSWYFLRFVDPHNKGALADYDHLKKWMPVDVYIGGAEHAVLHL  539
             G KG+RETNTMPQWAGSSWY+LR++DPHN   LAD + LK+W+PVD+Y+GGAEHAVLHL
Sbjct  480  DGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHL  539

Query  540  LYARFWHKFLYDIGVVPTKEPFQKLYNQGMILGTN-------------------------  574
            LYARFWHK LYD+GVVPTKEPFQKL+NQGMILGT+                         
Sbjct  540  LYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVE  599

Query  575  --------NEKMSKSRGNVINPDDVIEQYGADTLRLYEMFMGPLDASVAWSENGLEGSRK  626
                      KMSKS  NV+NPDDV+EQYGADTLR+YEMFMGPLDAS+AWSE+GLEGSRK
Sbjct  600  TGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRK  659

Query  627  FLDRVWRLCVDEDGKIRDRITTINDGSLTKVYNQTVKKVTEDFADLRFNTAISQLMVFVN  686
            FLDRV RL    +      IT  N G+L KVYN+TVK VTE+  +++FNTAI+QLMVFVN
Sbjct  660  FLDRVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVN  713

Query  687  EANKADSLYYGYIEGFVQLLAPVAPHLGEELWAILGNKG-GISYVSWPTYDESALVEDQV  745
             ANK D L+ +Y  GFVQL+AP APHLGEELW  L   G +ISYV+WP+YDES LVE++V
Sbjct  714  AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDV  773

Query  746  EVVLQINGRVRAKVQVPaeatkeeleelakSNPNIQEHLADK  787
            E+V+QI+G+V+AK+ V+ + ++EEL+E+A +N ++Q ++A+K
Sbjct  774  EIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGK  815

226) Bcoa_2427 in NC_016023


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  925 bits (3506),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 549/835 (66%), Positives = 671/835 (81%), Gaps = 42/835 (5%)

Query  3    FDHRKIEKKWQQYWEEHHTFRTGEDENKPKFYCLDMFPYPSGAGLHVGHPEGYTATDIVS  62
            +DH  IE KWQ +W ++HTF+TG D +KPKFY LDMFPYPSGAGLHVGHPEGYTATDI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RTKRMQGYNVLHPMGWDAFGLPAEQYAIDTGNDPAVFTIQNINTFRRQMKSIGFSYDWDR  122
            R KR QG NVLHPMGWDAFGLPAEQYA+DTGNDPA FT +NI  F+RQ++++GFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EINTSDPEYYKWTQWIFLQLWKKGLAYIDEVPVNWCPALGTVLANEEVI-DGKSERGGHP  181
            E+NT+DP+YYKWTQWIF +L  KGLAY  EVPVNW   LGT +ANEEV+ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VIRKPMRQWMLKITAYAdrlledleeldWPENIKDMQRNWIGRSEGAEVTFQVEGTNETF  241
            V+RKPMRQWMLKITAYA+RLLEDLEE+DWPE+IKDMQRNWIG+S GA+VTF+V +T+  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  TVFTTRPDTLFGATYAVLAPEHPLVDKIKTAEQADAVQAYIAEVQLKSDLERTDLAKDKT  301
            TVFTTRPDTLFGATYAVLAPEH+LVD I T++QA+AV  Y  +  LKSDL RTDLAK+KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAVNPANGEKMPIWIADYVLMSYGTGAIMAVPAHDERDYEFARKFDLPIKEVVA  361
            GV TG+YA+NP NG  MP+WIADYVL SYGTGAIMAVPAHDERD EFA++F+L I  V+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGNVEKEAYTGDGEHVHSGFLNGLDKQTAIKRMIEWLEEKGIGQKKVTYRLRDWLFSRQR  421
            GGNVE  A+T DG H++S+FL+GLDK +AI +M+EWLE  G+G+ +VTYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPVIHWEDGTITAVPEEELPLMLPKMKEIKPSGTGESPLANVEDWVNVVDPKTGK  481
            YWGEPIP+IHWEDGT TAVPE ELPL+LP  K+I+PSGTGESPLANV DW++V     G 
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT-REDGV  482

Query  482  KGRRETNTMPQWAGSCWYFLRFIDPKNHKAIADPEKLKKWLPVDLYIGGTEHAVLHLLYA  541
            KGRRETNTMPQWAGS WY+LR+IDP N   +AD E LK+WLPVD+Y+GG+EHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKFLYDIGVVSTKEPFQRLFNQGMILGAN----------------------------  573
            RFWHK LYD+GVV+TKEPFQ+LFNQGMILG++                            
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  574  -----HEKMSKSRGNVVNPDDILESHGADTLRLYEMFMGPLDASIPWSTNGLDGSRRFLD  628
                   KMSKS  NVVNPDD++E  GADTLR+YEMFMGPLDASI+WS +GL+GSR+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RIWRLFVNEDGSLSEKIQDKANPALEKTYHLTVKKVTEDIDALHFNTAISQLMVFINDAY  688
            R+ RL+   +      I +  + AL+K Y+ TVK VTE++D + FNTAI+QLMVF+N A 
Sbjct  663  RVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  689  KAEVIPKTYVEGFVKLLSPFCPHIAEELWEKLGHSG-TITYEAWPAFDASKLIENEVEIV  747
            K + +   Y  GFV+L++PF PH++EELW+ L  SG +I+Y +WP++D SKL+EN+VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  748  LQVNGKVRNKVKIDRNMSREDMEKLALADEKIKEFTEGKTIRKIIAVPGKLVNIV  802
            +Q++GKV+ K+ + +++SRE+++ +ALA+EK++    GK I K+IAVP KLVNIV
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIV  831

227) leuS in NC_014019


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  923 bits (3496),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 561/837 (68%), Positives = 669/837 (80%), Gaps = 42/837 (5%)

Query  3    FNHEKIEQKWQKVWEENKTFRTTEDEGKRKFYALDMFPYPSGAGLHVGHPEGYTATDILS  62
            ++H  IE KWQ  W +N TF+T  D +K KFYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMKRMQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTELNINNFRRQIKSLGFSYDWER  122
            R KR QG NVLHPMGWDAFGLPAEQYA+DTGNDPAEFT  NI NF+RQI++LGFSYDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EINTTDPNYYKWTQWIFLQLYKKGLAYVDEVAVNWCPALGTVLANEEVI-DGKSERGGHP  181
            E+NTTDPNYYKWTQWIF +LY KGLAY  EV+VNW   LGT +ANEEV+ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRPMKQWMLKITAYAdrlledldeldWPESIKEMQRNWIGRSEGAHVHFTIDGYDDTF  241
            V R+PM+QWMLKITAYA+RLLEDL+E+DWPESIK+MQRNWIG+S GA+V F + + D  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  TVFTTRPDTLFGATYAVLAPEHPFVEKITTAEQKEAVEAYLDQIKSKSDLERTDLAKDKT  301
            TVFTTRPDTLFGATYAVLAPEH++V+ ITT++Q EAV  Y  Q   KSDL RTDLAK+KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAINPVNGERMPIWIADYVLMSYGTGAIMAVPAHDERDYEFAVKFELPIKEVVA  361
            GV TG+YAINPVNG  MP+WIADYVL SYGTGAIMAVPAHDERD EFA +F+L I  V+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGDVSKEAYTGDGEHVNSDFLNGLDKEEAISNMIQWLQANEKGEKQVTYRLRDWLFSRQR  421
            GG+V   A+T DG H+NSDFL+GLDK  AI++M++WL+A+  G+ +VTYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPVIHWEDGTTTAVPEDQLPLVLPKTTEIKPSGTGESPLANIDDWVNVVDPETGK  481
            YWGEPIP+IHWEDGT+TAVPE +LPLVLP T +I+PSGTGESPLAN+ DW++V   E G 
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT-REDGV  482

Query  482  KGRRETNTMPQWAGSCWYYLRYIDPTNSEALADADKLKEWLPVDIYIGGAEHAVLHLLYA  541
            KGRRETNTMPQWAGS WYYLRYIDP N+E LAD + LK+WLPVDIY+GGAEHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKFLYDIGVVPTKEPFQKLFNQGMILG------------------------------  571
            RFWHK LYD+GVVPTKEPFQKLFNQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---ENNEKMSKSKGNVVNPDEIVESHGADTLRLYEMFMGPLDASIAWSTKGLDGARRFLD  628
               +   KMSKS  NVVNPD++VE  GADTLR+YEMFMGPLDASIAWS  GL+G+R+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RVWRLLVDDNGELSSKVQESNDTTLERVYHQTVKKVTEDYEGLRFNTGISQLMVFINDAY  688
            RV RL+       +  + E N  +L++VY++TVK VTE+ + ++FNT+I+QLMVF+N A 
Sbjct  663  RVYRLIT------TKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  689  KVDVLPKQYVEGFVKLLAPICPHTTEELWSKL-GHEDTISYEAWPAFDEAKLVDDEVEIV  747
            K D L  +Y  GFV+L+AP+ PH  EELW  L +  ++ISY +WP++DE+KLV+++VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  748  VQINGKVRAKVNVPAEASREELQDIAMANEDVKEFIEGKTVRKVIAVPGKLVNIVAN  804
            VQI+GKV+AK+ V+ + SREELQ++A+ANE V+  I GK + KVIAVP KLVNIV +
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

228) leuS in NC_015634


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  923 bits (3495),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 554/837 (67%), Positives = 669/837 (80%), Gaps = 42/837 (5%)

Query  3    FDHRKIEKKWQHYWEEHQTFRAGEDENKPKFYCLDMFPYPSGAGLHVGHPEGYTATDIIS  62
            +DH  IE KWQ +W +++TF++G D +KPKFY LDMFPYPSGAGLHVGHPEGYTATDI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RAKRMQGYNVLHPMGWDAFGLPAEQYAIDTGNDPAVFTIQNIHTFRRQIKALGFSYDWDR  122
            R KR QG NVLHPMGWDAFGLPAEQYA+DTGNDPA FT +NI  F+RQI+ALGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EINTSDPEYYKWTQWIFLQLWKNGLAYIDEVPVNWCPALGTVLANEEVI-DGKSERGGHP  181
            E+NT+DP+YYKWTQWIF +L  +GLAY  EVPVNW   LGT +ANEEV+ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VIRKPMRQWMLKITAYAdrlledleeldWPESIKDMQRNWIGRSEGAEVTFQVEGTNETF  241
            V+RKPMRQWMLKITAYA+RLLEDLEE+DWPESIKDMQRNWIG+S GA+VTF+V +T+  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  TVFTTRPDTLFGATYAVLAPEHPLVDKIKTKEQAEAVQAYIAQVQSKSDLERTDLAKEKT  301
            TVFTTRPDTLFGATYAVLAPEH+LVD I T +QAEAV  Y  Q   KSDL RTDLAKEKT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAVNPANGEKMPIWIADYVLMSYGTGAIMAVPAHDERDYEFARKFNLPIKEVVA  361
            GV TG+YA+NP NG  MP+WIADYVL SYGTGAIMAVPAHDERD EFA++FNL I  V+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGNVEKEAYTGDGEHVHSGFLNGLGKQAAIKRMIEWLEEKGIGQKKVTYRLRDWLFSRQR  421
            GGNVE  A+T DG H++S+FL+GL+K +AI +M+EWLE  G+G+ +VTYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPVIHWEDGTITAVPEEELPLMLPKMTEIKPSGTGESPLANVEEWVNVVDPETGK  481
            YWGEPIP+IHWEDGT TAVPE ELPL+LP   +I+PSGTGESPLANV +W++V   E G 
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT-REDGV  482

Query  482  KGRRETNTMPQWAGSCWYFLRFIDPKNRKAIADPEKLKKWLPVDLYIGGAEHAVLHLLYA  541
            KGRRETNTMPQWAGS WY+LR+IDP N   +AD E LK+WLPVD+Y+GGAEHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKFLYDIGVVPTKEPFQRLFNQGMILG------------------------------  571
            RFWHK LYD+GVVPTKEPFQ+LFNQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---ENHEKMSKSRGNVVNPDDILESHGADTLRLYEMFMGPLDASIPWSTNGLDGSRRFLD  628
               +   KMSKS  NVVNPDD++E  GADTLR+YEMFMGPLDASI+WS +GL+GSR+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RIWRLFVNEDGSLSEKIQDKANPALEKTYHLTVKKVTEDIDALHFNTAISQLMVFINDAY  688
            R+ RL+   +      I +  + AL+K Y+ TVK VTE++D + FNTAI+QLMVF+N A 
Sbjct  663  RVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  689  KAEVIPKTYVEGFVKLLSPFCPHIAEELWEKLGHSG-TITYEAWPSFDASKLVDNEVEIV  747
            K + +   Y  GFV+L++PF PH++EELW+ L  SG +I+Y +WPS+D SKLV+N+VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  748  LQVNGKVRNKVKIDRNMSREDMEKLALADEKIKEFTEGKTIRKIIAVPGKLVNIVAN  804
            +Q++GKV+ K+ + +++SRE+++ +ALA+EK++    GK I K+IAVP KLVNIV +
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

229) leuS in NC_014103


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  923 bits (3496),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 560/837 (67%), Positives = 669/837 (80%), Gaps = 42/837 (5%)

Query  3    FNHEKIEQKWQKVWEENKTFRTTEDEGKRKFYALDMFPYPSGAGLHVGHPEGYTATDILS  62
            ++H  IE KWQ  W +N TF+T  D +K KFYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMKRMQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTELNINNFRRQIKSLGFSYDWER  122
            R KR QG NVLHPMGWDAFGLPAEQYA+DTGNDPAEFT  NI NF+RQI++LGFSYDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EINTTDPNYYKWTQWIFLQLYKNGLAYVDEVAVNWCPALGTVLANEEVI-DGKSERGGHP  181
            E+NTTDPNYYKWTQWIF +LY +GLAY  EV+VNW   LGT +ANEEV+ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRPMKQWMLKITAYAdrlledldeldWPESIKEMQRNWIGRSEGAHVHFTIDGYEDTF  241
            V R+PM+QWMLKITAYA+RLLEDL+E+DWPESIK+MQRNWIG+S GA+V F + + +  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  TVFTTRPDTLFGATYAVLAPEHPFVEKITTAEQKEAVEAYLDQIKSKSDLERTDLAKDKT  301
            TVFTTRPDTLFGATYAVLAPEH++V+ ITT++Q EAV  Y  Q   KSDL RTDLAK+KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAINPVNGERMPIWIADYVLMSYGTGAIMAVPAHDERDYEFAVKFELPIKEVVA  361
            GV TG+YAINPVNG  MP+WIADYVL SYGTGAIMAVPAHDERD EFA +F+L I  V+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGDVSKEAYTGDGEHVNSDFLNGLDKEEAISNMIQWLQANEKGEKQVTYRLRDWLFSRQR  421
            GG+V   A+T DG H+NSDFL+GLDK  AI++M++WL+A+  G+ +VTYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPVIHWEDGTTTAVPEDQLPLVLPKTTEIKPSGTGESPLANIDDWVNVVDPETGK  481
            YWGEPIP+IHWEDGT+TAVPE +LPLVLP T +I+PSGTGESPLAN+ DW++V   E G 
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT-REDGV  482

Query  482  KGRRETNTMPQWAGSCWYYLRYIDPTNSEALADADKLKEWLPVDIYIGGAEHAVLHLLYA  541
            KGRRETNTMPQWAGS WYYLRYIDP N+E LAD + LK+WLPVDIY+GGAEHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKFLYDIGVVPTKEPFQKLFNQGMILG------------------------------  571
            RFWHK LYD+GVVPTKEPFQKLFNQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---ENNEKMSKSKGNVVNPDEIVESHGADTLRLYEMFMGPLDASIAWSTKGLDGARRFLD  628
               +   KMSKS  NVVNPD++VE  GADTLR+YEMFMGPLDASIAWS  GL+G+R+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RVWRLLVDDNGELSSKVQESNDTTLERVYHQTVKKVTEDYEGLRFNTGISQLMVFINDAY  688
            RV RL+       +  + E N  +L++VY++TVK VTE+ + ++FNT+I+QLMVF+N A 
Sbjct  663  RVYRLIT------TKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  689  KVDVLPKQYVEGFVKLLAPICPHTTEELWSKL-GHEDTISYEAWPAFDEAKLVDDEVEIV  747
            K D L  +Y  GFV+L+AP+ PH  EELW  L +  ++ISY +WP++DE+KLV+++VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  748  VQINGKVRAKVNVPAEASREELQDIAMANEDVQEFIEGKTVRKVIAVPGKLVNIVAN  804
            VQI+GKV+AK+ V+ + SREELQ++A+ANE VQ  I GK + KVIAVP KLVNIV +
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

230) leuS in NC_020210


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  919 bits (3482),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 558/838 (67%), Positives = 672/838 (81%), Gaps = 43/838 (5%)

Query  3    FNHREIEQKWQDYWEKNKTFRTSDDDDKPKFYVLDMFPYPSGAGLHVGHPEGYTATDILA  62
            ++H  IE KWQ +W  N TF+T+ D  KPKFY LDMFPYPSGAGLHVGHPEGYTATDIL+
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMKRMQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTQKNIDNFRRQIKSLGFSYDWDR  122
            R KR QG NVLHPMGWDAFGLPAEQYA+DTGNDPAEFT  NI NF+RQI++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EINTTDPNYYKWTQWIFLKLYEKGLAYMDEVPVNWCPALGTVLANEEVI-NGRSERGGHP  181
            E+NTTDPNYYKWTQWIF KLYEKGLAY  EVPVNW   LGT +ANEEV+ +G SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VIRKPMRQWMLKITAYAdrlledleeldWPESIKEMQRNWIGRSEGAEIEFAVDGHDETF  241
            V+RKPMRQWMLKITAYA+RLLEDLEE+DWPESIK+MQRNWIG+S GA++ F V + D  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  TVFTTRPDTLFGATYTVLAPEHPLVEKITTPEQKPAVDAYLKEIQSKSDLERTDLAKEKT  301
            TVFTTRPDTLFGATY+VLAPEH+LV+ ITT++Q  AV  Y ++   KSDL RTDLAKEKT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAIHPVTGDRLPIWIADYVLMSYGTGAIMAVPAHDERDYEFAKKFHLPMKEVVA  361
            GV TG+YAI+PV G  +P+WIADYVL SYGTGAIMAVPAHDERD EFAK+F+L +  V+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGDIEKEPYTGDGEHINSEFLNGLNKQEAIDKMIAWLEEHGKGRKKVSYRLRDWLFSRQR  421
            GG++E  ++T DG HINS+FL+GL+K  AI KM+ WLE +G G  +V+YRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPIIHWEDGTMTpvpeeelplvlpKTDEIRPSGTGESPLANIEEWVNVVDPKTGK  481
            YWGEPIPIIHWEDGT T+VPE ELPLVLP T +IRPSGTGESPLAN+ +W++V     G 
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT-REDGV  482

Query  482  KGRRETNTMPQWAGSCWYYLRYIDPHNDKQLADPEKLKKWLPVDVYIGGAEHAVLHLLYA  541
            KGRRETNTMPQWAGS WYYLRYIDPHN  +LAD E LK+WLPVD+Y+GGAEHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKFLYDLGIVPTKEPFQKLFNQGMILG------------------------------  571
            RFWHK LYDLG+VPTKEPFQKLFNQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---ENNEKMSKSKGNVVNPDDIIESHGADTLRLYEMFMGPLEASIAWSTKGLDGARRFLD  628
               +   KMSKS  NVVNPDD++E  GADTLR+YEMFMGPL+ASIAWS  GL+G+R+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RVWRLFVTENGELNPNIVDEPANDTLERIYHQTVKKVTEDYESLRFNTAISQLMVFINEA  688
            RV RL+ T +       + E  +++L+++Y++TVK VTE+ + ++FNTAI+QLMVF+N A
Sbjct  663  RVYRLITTKE-------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAA  715

Query  689  YKAEQMKKEYMEGFVKLLSPVCPHIGEELWQKL-GHTDTIAYEPWPTYDETKLVEDVVEI  747
             K +++  +Y  GFV+L++P  PH+GEELWQ L +  ++I+Y PWP+YDE+KLVE+ VEI
Sbjct  716  NKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEI  775

Query  748  VVQINGKVRSRLHVPVDLPKEALEERALADEKIKEQLEGKTVRKVIAVPGKLVNIVAN  805
            VVQI+GKV+++L V+ DL++E L+E ALA+EK++ ++ GK + KVIAVP KLVNIV +
Sbjct  776  VVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

231) GTCCBUS3UF5_31990 in NC_016593


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  919 bits (3483),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 560/838 (67%), Positives = 672/838 (81%), Gaps = 43/838 (5%)

Query  3    FNHREIEQKWQDYWEKNKTFRTSDDDDKPKFYVLDMFPYPSGAGLHVGHPEGYTATDILA  62
            ++H  IE KWQ +W  N TF+T+ D  KPKFY LDMFPYPSGAGLHVGHPEGYTATDIL+
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMKRMQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTQKNIDNFRRQIKSLGFSYDWDR  122
            R KR QG NVLHPMGWDAFGLPAEQYA+DTGNDPAEFT  NI NF+RQI++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EINTTDPNYYKWTQWIFLKLYEKGLAYMDEVPVNWCPALGTVLANEEVI-NGRSERGGHP  181
            E+NTTDPNYYKWTQWIF KLYEKGLAY  EVPVNW   LGT +ANEEV+ +G SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VIRKPMRQWMLKITAYAdrlledleeldWPESIKEMQRNWIGRSEGAEIEFAVDGHDETF  241
            V+RKPMRQWMLKITAYA+RLLEDLEE+DWPESIK+MQRNWIG+S GA++ F V + D  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  TVFTTRPDTLFGATYTVLAPEHPLVEKITTPEQKPAVDAYLKEIQSKSDLERTDLAKEKT  301
            TVFTTRPDTLFGATY+VLAPEH+LV+ ITT++Q  AV  Y ++   KSDL RTDLAKEKT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAIHPVTGDRLPIWIADYVLMSYGTGAIMAVPAHDERDYEFAKKFHLPMKEVVA  361
            GV TG+YAI+PV G  +P+WIADYVL SYGTGAIMAVPAHDERD EFAK+F+L +  V+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGNIEKEAYTGDGEHINSEFLNGLNKQEAIDKMIAWLEEHGKGRKKVSYRLRDWLFSRQR  421
            GGN+E  A+T DG HINS+FL+GL+K  AI KM+ WLE +G G  +V+YRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPIIHWEDGTMTpvpeeelplvlpKTDEIRPSGTGESPLANIEEWVNVVDPKTGK  481
            YWGEPIPIIHWEDGT T+VPE ELPLVLP T +IRPSGTGESPLAN+ +W++V     G 
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT-REDGV  482

Query  482  KGRRETNTMPQWAGSCWYYLRYIDPHNDKQLADPEKLKKWLPVDVYIGGAEHAVLHLLYA  541
            KGRRETNTMPQWAGS WYYLRYIDPHN  +LAD E LK+WLPVD+Y+GGAEHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKFLYDLGIVPTKEPFQKLFNQGMILG------------------------------  571
            RFWHK LYDLG+VPTKEPFQKLFNQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---ENNEKMSKSKGNVVNPDDIIESHGADTLRLYEMFMGPLEASIAWSTKGLDGARRFLD  628
               +   KMSKS  NVVNPDD++E  GADTLR+YEMFMGPL+ASIAWS  GL+G+R+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RVWRLFVTENGELNPNIVDEPANDTLERIYHQTVKKVTEDYEALRFNTAISQLMVFINEA  688
            RV RL+ T +       + E  +++L+++Y++TVK VTE+ + ++FNTAI+QLMVF+N A
Sbjct  663  RVYRLITTKE-------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAA  715

Query  689  YKAEQMKKEYMEGFVKLLSPVCPHIGEELWQKL-GHTDTIAYEPWPTYDETKLVEDVVEI  747
             K +++  +Y  GFV+L++P  PH+GEELWQ L +  ++I+Y PWP+YDE+KLVE+ VEI
Sbjct  716  NKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEI  775

Query  748  VVQINGKVRSRLHVPVDLPKEALEERALADEKIKEQLEGKTVRKVIAVPGKLVNIVAN  805
            VVQI+GKV+++L V+ DL++E L+E ALA+EK++ ++ GK + KVIAVP KLVNIV +
Sbjct  776  VVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

232) GYMC52_2888 in NC_014915


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  919 bits (3481),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 561/838 (67%), Positives = 671/838 (81%), Gaps = 43/838 (5%)

Query  3    FNHREIEQKWQDYWEKNKTFRTPDDDDKPKFYVLDMFPYPSGAGLHVGHPEGYTATDILA  62
            ++H  IE KWQ +W  N TF+T  D  KPKFY LDMFPYPSGAGLHVGHPEGYTATDIL+
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMKRMQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTQKNIDNFRRQIKSLGFSYDWDR  122
            R KR QG NVLHPMGWDAFGLPAEQYA+DTGNDPAEFT  NI NF+RQI++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EINTTDPNYYKWTQWIFLKLYEKGLAYMDEVPVNWCPALGTVLANEEVI-NGRSERGGHP  181
            E+NTTDPNYYKWTQWIF KLYEKGLAY  EVPVNW   LGT +ANEEV+ +G SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VIRKPMRQWMLKITAYAdrlledleeldWPESIKEMQRNWIGRSEGAEIEFAVDGHDETF  241
            V+RKPMRQWMLKITAYA+RLLEDLEE+DWPESIK+MQRNWIG+S GA++ F V + D  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  TVFTTRPDTLFGATYTVLAPEHPLVEKITTPEQKPAVDAYLKEIQSKSDLERTDLAKEKT  301
            TVFTTRPDTLFGATY+VLAPEH+LV+ ITT++Q  AV  Y ++   KSDL RTDLAKEKT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAIHPVTGDRLPIWIADYVLMSYGTGAIMAVPAHDERDYEFAKKFHLPMKEVVA  361
            GV TG+YAI+PV G  +P+WIADYVL SYGTGAIMAVPAHDERD EFAK+F+L +  V+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGNIEKEAYTGDGEHINSEFLNGLNKQEAIDKMIAWLEEHGKGRKKVSYRLRDWLFSRQR  421
            GGN+E  A+T DG HINS+FL+GL+K  AI KM+ WLE +G G  +V+YRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPIIHWEDGTMTpvpeeelplvlpKTDEIRPSGTGESPLANIEEWVNVVDPKTGK  481
            YWGEPIPIIHWEDGT T+VPE ELPLVLP T +IRPSGTGESPLAN+ +W++V     G 
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT-REDGV  482

Query  482  KGRRETNTMPQWAGSCWYYLRYIDPHNDKQLADPEKLKKWLPVDVYIGGAEHAVLHLLYA  541
            KGRRETNTMPQWAGS WYYLRYIDPHN  +LAD E LK+WLPVD+Y+GGAEHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKFLYDLGIVPTKEPFQKLFNQGMILG------------------------------  571
            RFWHK LYDLG+VPTKEPFQKLFNQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---ENNEKMSKSKGNVVNPDDIIESHGADTLRLYEMFMGPLEASIAWSTKGLDGARRFLD  628
               +   KMSKS  NVVNPDD++E  GADTLR+YEMFMGPL+ASIAWS  GL+G+R+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RVWRLFVTENGELNPNIVDEPANDTLERVYHQTVKKVTEDYEALRFNTAISQLMVFINEA  688
            RV RL+ T +       + E  +++L++VY++TVK VTE+ + ++FNTAI+QLMVF+N A
Sbjct  663  RVYRLITTKE-------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAA  715

Query  689  YKAEQMKKEYMEGFVKLLSPVCPHIGEELWQKL-GHTDTIAYEPWPTYDETKLVEDVVEI  747
             K +++  +Y  GFV+L++P  PH+GEELWQ L +  ++I+Y PWP+YDE+KLVE+ VEI
Sbjct  716  NKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEI  775

Query  748  VVQINGKVRSRLHVPVDLPKEALEERALADEKIKEQLEGKTVRKVIAVPGKLVNIVAN  805
            VVQI+GKV+++L V+ DL++E L+E ALA+EK++ ++ GK + KVIAVP KLVNIV +
Sbjct  776  VVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

233) leuS in NC_013411


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  919 bits (3481),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 561/838 (67%), Positives = 671/838 (81%), Gaps = 43/838 (5%)

Query  3    FNHREIEQKWQDYWEKNKTFRTPDDDDKPKFYVLDMFPYPSGAGLHVGHPEGYTATDILA  62
            ++H  IE KWQ +W  N TF+T  D  KPKFY LDMFPYPSGAGLHVGHPEGYTATDIL+
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMKRMQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTQKNIDNFRRQIKSLGFSYDWDR  122
            R KR QG NVLHPMGWDAFGLPAEQYA+DTGNDPAEFT  NI NF+RQI++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EINTTDPNYYKWTQWIFLKLYEKGLAYMDEVPVNWCPALGTVLANEEVI-NGRSERGGHP  181
            E+NTTDPNYYKWTQWIF KLYEKGLAY  EVPVNW   LGT +ANEEV+ +G SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VIRKPMRQWMLKITAYAdrlledleeldWPESIKEMQRNWIGRSEGAEIEFAVDGHDETF  241
            V+RKPMRQWMLKITAYA+RLLEDLEE+DWPESIK+MQRNWIG+S GA++ F V + D  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  TVFTTRPDTLFGATYTVLAPEHPLVEKITTPEQKPAVDAYLKEIQSKSDLERTDLAKEKT  301
            TVFTTRPDTLFGATY+VLAPEH+LV+ ITT++Q  AV  Y ++   KSDL RTDLAKEKT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAIHPVTGDRLPIWIADYVLMSYGTGAIMAVPAHDERDYEFAKKFHLPMKEVVA  361
            GV TG+YAI+PV G  +P+WIADYVL SYGTGAIMAVPAHDERD EFAK+F+L +  V+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGNIEKEAYTGDGEHINSEFLNGLNKQEAIDKMIAWLEEHGKGRKKVSYRLRDWLFSRQR  421
            GGN+E  A+T DG HINS+FL+GL+K  AI KM+ WLE +G G  +V+YRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPIIHWEDGTMTpvpeeelplvlpKTDEIRPSGTGESPLANIEEWVNVVDPKTGK  481
            YWGEPIPIIHWEDGT T+VPE ELPLVLP T +IRPSGTGESPLAN+ +W++V     G 
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT-REDGV  482

Query  482  KGRRETNTMPQWAGSCWYYLRYIDPHNDKQLADPEKLKKWLPVDVYIGGAEHAVLHLLYA  541
            KGRRETNTMPQWAGS WYYLRYIDPHN  +LAD E LK+WLPVD+Y+GGAEHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKFLYDLGIVPTKEPFQKLFNQGMILG------------------------------  571
            RFWHK LYDLG+VPTKEPFQKLFNQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---ENNEKMSKSKGNVVNPDDIIESHGADTLRLYEMFMGPLEASIAWSTKGLDGARRFLD  628
               +   KMSKS  NVVNPDD++E  GADTLR+YEMFMGPL+ASIAWS  GL+G+R+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RVWRLFVTENGELNPNIVDEPANDTLERVYHQTVKKVTEDYEALRFNTAISQLMVFINEA  688
            RV RL+ T +       + E  +++L++VY++TVK VTE+ + ++FNTAI+QLMVF+N A
Sbjct  663  RVYRLITTKE-------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAA  715

Query  689  YKAEQMKKEYMEGFVKLLSPVCPHIGEELWQKL-GHTDTIAYEPWPTYDETKLVEDVVEI  747
             K +++  +Y  GFV+L++P  PH+GEELWQ L +  ++I+Y PWP+YDE+KLVE+ VEI
Sbjct  716  NKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEI  775

Query  748  VVQINGKVRSRLHVPVDLPKEALEERALADEKIKEQLEGKTVRKVIAVPGKLVNIVAN  805
            VVQI+GKV+++L V+ DL++E L+E ALA+EK++ ++ GK + KVIAVP KLVNIV +
Sbjct  776  VVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

234) GC56T3_0651 in NC_014206


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  918 bits (3479),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 560/838 (67%), Positives = 671/838 (81%), Gaps = 43/838 (5%)

Query  3    FNHREIEQKWQDYWEKNKTFRTPDDDDKPKFYVLDMFPYPSGAGLHVGHPEGYTATDILA  62
            ++H  IE KWQ +W  N TF+T  D  KPKFY LDMFPYPSGAGLHVGHPEGYTATDIL+
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMKRMQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTQKNIDNFRRQIKSLGFSYDWDR  122
            R KR QG NVLHPMGWDAFGLPAEQYA+DTGNDPAEFT  NI NF+RQI++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EINTTDPNYYKWTQWIFLKLYEKGLAYMDEVPVNWCPALGTVLANEEVI-NGRSERGGHP  181
            E+NTTDPNYYKWTQWIF KLYEKGLAY  EVPVNW   LGT +ANEEV+ +G SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VIRKPMRQWMLKITAYAdrlledleeldWPESIKEMQRNWIGRSEGAEIEFAVDGHDETF  241
            V+RKPMRQWMLKITAYA+RLLEDLEE+DWPESIK+MQRNWIG+S GA++ F V + D  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  TVFTTRPDTLFGATYTVLAPEHPLVEKITTPEQKPAVDAYLKEIQSKSDLERTDLAKEKT  301
            TVFTTRPDTLFGATY+VLAPEH+LV+ ITT++Q  AV  Y ++   KSDL RTDLAKEKT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAIHPVTGARLPIWIADYVLMSYGTGAIMAVPAHDERDYEFAKKFHLPMKEVVA  361
            GV TG+YAI+PV G  +P+WIADYVL SYGTGAIMAVPAHDERD EFAK+F+L +  V+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGNIEKEAYTGDGEHINSEFLNGLNKQEAIDKMIAWLEEHGKGRKKVSYRLRDWLFSRQR  421
            GGN+E  A+T DG HINS+FL+GL+K  AI KM+ WLE +G G  +V+YRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPIIHWEDGTMTpvpeeelplvlpKTDEIRPSGTGESPLANIEEWVNVVDPKTGK  481
            YWGEPIPIIHWEDGT T+VPE ELPLVLP T +IRPSGTGESPLAN+ +W++V     G 
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT-REDGV  482

Query  482  KGRRETNTMPQWAGSCWYYLRYIDPHNDKQLADPEKLKKWLPVDVYIGGAEHAVLHLLYA  541
            KGRRETNTMPQWAGS WYYLRYIDPHN  +LAD E LK+WLPVD+Y+GGAEHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKFLYDLGIVPTKEPFQKLFNQGMILG------------------------------  571
            RFWHK LYDLG+VPTKEPFQKLFNQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---ENNEKMSKSKGNVVNPDDIIESHGADTLRLYEMFMGPLEASIAWSTKGLDGARRFLD  628
               +   KMSKS  NVVNPDD++E  GADTLR+YEMFMGPL+ASIAWS  GL+G+R+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RVWRLFVTENGELNPNIVDEPANDTLERIYHQTVKKVTEDYEALRFNTAISQLMVFINEA  688
            RV RL+ T +       + E  +++L+++Y++TVK VTE+ + ++FNTAI+QLMVF+N A
Sbjct  663  RVYRLITTKE-------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAA  715

Query  689  YKAEQMKKEYMEGFVKLLSPVCPHIGEELWQKL-GHTDTIAYEPWPTYDETKLVEDVVEI  747
             K +++  +Y  GFV+L++P  PH+GEELWQ L +  ++I+Y PWP+YDE+KLVE+ VEI
Sbjct  716  NKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEI  775

Query  748  VVQINGKVRSRLHVPVDLPKEALEERALADEKIKEQLEGKTVRKVIAVPGKLVNIVAN  805
            VVQI+GKV+++L V+ DL++E L+E ALA+EK++ ++ GK + KVIAVP KLVNIV +
Sbjct  776  VVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

235) leuS in NC_006510


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  918 bits (3478),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 558/838 (67%), Positives = 671/838 (81%), Gaps = 43/838 (5%)

Query  3    FNHREIEQKWQDYWEKNKTFRTPDDDDKPKFYVLDMFPYPSGAGLHVGHPEGYTATDILA  62
            ++H  IE KWQ +W  N TF+T  D  KPKFY LDMFPYPSGAGLHVGHPEGYTATDIL+
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMKRMQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTQKNIDNFRRQIKSLGFSYDWDR  122
            R KR QG NVLHPMGWDAFGLPAEQYA+DTGNDPAEFT  NI NF+RQI++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EINTTDPNYYKWTQWIFLKLYEKGLAYMDEVPVNWCPALGTVLANEEVI-NGRSERGGHP  181
            E+NTTDPNYYKWTQWIF KLYEKGLAY  EVPVNW   LGT +ANEEV+ +G SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VIRKPMRQWMLKITAYAdrlledleeldWPESIKEMQRNWIGRSEGAEIEFAVHGHDETF  241
            V+RKPMRQWMLKITAYA+RLLEDLEE+DWPESIK+MQRNWIG+S GA++ F V + D  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  TVFTTRPDTLFGATYTVLAPEHPLVEKITTPEQKPAVDAYLKEIQSKSDLERTDLAKEKT  301
            TVFTTRPDTLFGATY+VLAPEH+LV+ ITT++Q  AV  Y ++   KSDL RTDLAKEKT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAIHPVTGDRLPIWIADYVLMSYGTGAIMAVPAHDERDYEFAKKFHLPMKEVVA  361
            GV TG+YAI+PV G  +P+WIADYVL SYGTGAIMAVPAHDERD EFAK+F+L +  V+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGDIEKEPYTGDGEHINSEFLNGLNKQEAIDKMIAWLEEHGKGRKKVSYRLRDWLFSRQR  421
            GG++E  ++T DG HINS+FL+GL+K  AI KM+ WLE +G G  +V+YRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPIIHWEDGTMTpvpeeelplvlpKTDEIRPSGTGESPLANIEEWVNVVDPKTGK  481
            YWGEPIPIIHWEDGT T+VPE ELPLVLP T +IRPSGTGESPLAN+ +W++V     G 
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT-REDGV  482

Query  482  KGRRETNTMPQWAGSCWYYLRYIDPHNDKQLADPEKLKKWLPVDVYIGGAEHAVLHLLYA  541
            KGRRETNTMPQWAGS WYYLRYIDPHN  +LAD E LK+WLPVD+Y+GGAEHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKFLYDLGIVPTKEPFQKLFNQGMILG------------------------------  571
            RFWHK LYDLG+VPTKEPFQKLFNQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---ENNEKMSKSKGNVVNPDDIIESHGADTLRLYEMFMGPLEASIAWSTKGLDGARRFLD  628
               +   KMSKS  NVVNPDD++E  GADTLR+YEMFMGPL+ASIAWS  GL+G+R+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RVWRLFVTENGELNPNIVDEPANDTLERIYHQTVKKVTEDYESLRFNTAISQLMVFINEA  688
            RV RL+ T +       + E  +++L+++Y++TVK VTE+ + ++FNTAI+QLMVF+N A
Sbjct  663  RVYRLITTKE-------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAA  715

Query  689  YKAEQMKKEYMEGFVKLLSPVCPHIGEELWQKL-GHTDTIAYEPWPTYDETKLVEDVVEI  747
             K +++  +Y  GFV+L++P  PH+GEELWQ L +  ++I+Y PWP+YDE+KLVE+ VEI
Sbjct  716  NKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEI  775

Query  748  VVQINGKVRSRLHVPVDLPKEALEERALADEKIKEQLEGKTVRKVIAVPGKLVNIVAN  805
            VVQI+GKV+++L V+ DL++E L+E ALA+EK++ ++ GK + KVIAVP KLVNIV +
Sbjct  776  VVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

236) leuS in NC_015278


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  917 bits (3473),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 565/837 (68%), Positives = 683/837 (82%), Gaps = 42/837 (5%)

Query  3    YNHKTIEKKWQKYWKDNKSFKTLEDKSLPKFYALDMFPYPSGQGLHVGHPEGYTATDIVS  62
            Y+H +IE KWQ +W DN +FKT  D S PKFYALDMFPYPSG GLHVGHPEGYTATDI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMKRAQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTQANIEVFKKQIESLGFSYDWDR  122
            R KRAQG NVLHPMGWDAFGLPAEQYA+DTGNDPAEFT  NI  FK+QI++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EIDTTDPEYYKWTQWIFTKLFEKGLAYEDEIMVNWCEALGTVLANEEVI-DGLSERGNHP  181
            E++TTDP+YYKWTQWIFTKL+EKGLAYE E+ VNW E LGT +ANEEV+ DG SERG  P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VVRRPMKQWVLKITAYAdrlldglddldWPESIKEMQRNWIGRSEGADVTFKVADTDKEF  241
            VVR+PM+QW+LKITAYA+RLL++L+++DWPESIK+MQRNWIG+S GA+VTFKV DTDK+F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  EVFTTRPDTLYGATYCALAPEHPLIKQIVSEDQKQAVADYVEAASHKSDLERTDLAKEKT  301
             VFTTRPDTL+GATY  LAPEH+L+  I + DQ +AVADY   AS KSDL RTDLAKEKT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAVNPLNGDKLPIWVADYVLVSYGSGAVMAVPAHDQRDYEFAKQFDLPIKAVIE  361
            GV TG+YA+NP+NG  +P+W+ADYVL SYG+GA+MAVPAHD+RD EFAKQF+L I +V+E
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGDLEKEAYTGDEVHIHSEELDGLVKDeaiekaielleakGAGQAKTSYRLRDWVFSRQR  421
            GG++E  A+T D +HI+S+ LDGL K  AI K +E LEA G G+ + +YRLRDW+FSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPVIHWEDGTTTAVPEADLPVLLPEGKDIKPSGTGESPLANFDDWLNVYDEETGL  481
            YWGEPIP+IHWEDGT+TAVPE++LP++LP  KDI+PSGTGESPLAN  DWL+V   E G+
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV-TREDGV  482

Query  482  HGKRETNTMPQWAGSSWYYIRFCDPKNNEELISQEAANYWMNVDLYIGGAEHAVLHLLYA  541
             G+RETNTMPQWAGSSWYY+R+ DP N E L  +E  + W+ VD+Y+GGAEHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWNMFLYDLGVVPTEEPFQKLFNQGMILG------------------------------  571
            RFW+  LYDLGVVPT EPFQKLFNQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---EGHEKMSKSKGNVVNPDDIVERYGADTLRLYEMFMGPLDASIAWSEDGLAGARRFLE  628
               ++  KMSKS  NVVNPDD+VE+YGADTLR+YEMFMGPLDASIAWSE+GL G+R+FL+
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RVWRLFVDSEDQLRDRITTIDTGELDKVYNQTVKKVTEDLEKLHFNTAISQMMVFVNEAN  688
            RV RL+   E      IT  ++G LDKVYN+TVK VTE+++++ FNTAI+Q+MVFVN AN
Sbjct  663  RVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  689  KAESIPYDYAKGFVQLLAPIAPHLGEELWQRLTGEA-GISYVPWPSYDESQLVEESIEIV  747
            K + +  DYAKGFVQL+AP+APHLGEELWQ LT+ + +ISYVPWPSYDES+LVE+ +EIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  748  VQVNGKIKERLQVASGLSQEELSQAAKDSDKVQAAIAGKDVVKVIAVPDKLVNIVVK  804
            VQ++GK+K +L VA +LS+EEL + A  ++KVQA IAGKD++KVIAVP+KLVNIV+K
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

237) leuS in NC_014639


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  916 bits (3469),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 563/837 (68%), Positives = 666/837 (80%), Gaps = 42/837 (5%)

Query  3    FQHKEIEKKWQNYWLENKTFATLEDNEKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  62
            ++H  IE KWQ +W +N TF T  D  KPKFYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMKRMQGYDVLHPMGWDAFGLPAEQYALDTGNDPAIFTKQNIDNFRRQIQALGFSYDWDR  122
            R KR QG +VLHPMGWDAFGLPAEQYA+DTGNDPA FT +NI NF+RQI+ALGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EINTTDPGYYKWTQWIFLKLYEKGLAYVDEVPVNWCPALGTVLANEEII-DGKSERGGHP  181
            E+NTTDP YYKWTQWIF KLYEKGLAY  EVPVNW   LGT +ANEE++ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRPMRQWMLKITAYAdrllddleeldWPESIKDMQRNWIGRSEGAHVHFDIEGHHESF  241
            V R+PMRQWMLKITAYA+RLL+DLEE+DWPESIKDMQRNWIG+S GA+V F + + +  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  TVFTTRPDTLFGATYTVLAPEHALVEKITTAEQKEAVEAYIKEVQSKSDLERTDLAKTKT  301
            TVFTTRPDTLFGATY+VLAPEHALV+ ITT++Q EAV  Y ++   KSDL RTDLAK KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAINPVNGEKMPIWIADYVLASYGTGAVMAVPGHDERDFEFAKVFGLPvkevvk  361
            GV TG+YAINPVNG  MP+WIADYVLASYGTGA+MAVP+HDERD EFAK F L +  V+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  ggnveeeAYTGDGEHVNSDFLNGLGKQEAIEKMIAWLEETKHGEKKVTYRLRDWLFSRQR  421
            GGNVEE A+T DG H+NSDFL+GL+K  AI KM+ WLE    G+ +VTYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPIIHWEDGTSTAVPEEELPLILPKTSEIKPSGTGESPLANIKDWVEVTDPETGK  481
            YWGEPIPIIHWEDGTSTAVPE ELPL+LP T +I+PSGTGESPLAN+ DW+EVT  E G 
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT-REDGV  482

Query  482  KGRRETNTMPQWAGSCWYFLRYIDPHNPDQLASPEKLDKWLPVDMYIGGAEHAVLHLLYA  541
            KGRRETNTMPQWAGS WY+LRYIDPHN ++LA  E L +WLPVD+Y+GGAEHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKFLYDIGVVPTKEPFQQLYNQGMILG------------------------------  571
            RFWHK LYD+GVVPTKEPFQ+L+NQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---ENNEKMSKSKGNVVNPDEIVSSHGADTLRLYEMFMGPLDASIAWSESGLDGARRFLD  628
               +   KMSKS  NVVNPD++V   GADTLR+YEMFMGPLDASIAWSE GL+G+R+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RVWRLFIEDSGELNSKITEGASETLERVYHETVMKVTDHYEGLRFNTGISQLMVFINEAY  688
            RV RL+          ITE  S +L++VY+ETV  VT++ + ++FNT+I+QLMVF+N A 
Sbjct  663  RVYRLIT------TKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  689  KASELPKEYVEGFVKLLSPVAPHLAEELWTRLGHTG-SIAYESWPVYDESKLIDDEIEIV  747
            K   L  +Y  GFV+L++P APHL+EELW  L  +G SI+Y +WP YDESKL+++++EIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  748  VQLNGKVKAKLQVPADATKDQLEQLAKDDEKVKEQLEGKTIRKVIAVPGKLVNIVAN  804
            VQ++GKVKAKL V+ D ++++L+++A  +EKV+ ++ GK I KVIAVP KLVNIV +
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

238) leuS in NC_011725


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  916 bits (3471),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 549/818 (68%), Positives = 655/818 (81%), Gaps = 44/818 (5%)

Query  3    FNHQEIEKKWQGYWEENKTFRTPDETEKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  62
            ++H  IE KWQ++W +N TF+T  ++ KPKFYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMKRMQGYNVLHPMGWDAFGLPAEQYALDTGNSPAEFTEHNINTFRNQIKSLGFSYDWDR  122
            R KR QG NVLHPMGWDAFGLPAEQYA+DTGN PAEFT +NI  F+ QI++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVNTTDPNYYKWTQWIFLKLFEKGLAYVDEVPVNWCPALGTVLANEEII-DGKSERGGHP  181
            EVNTTDPNYYKWTQWIF KL+EKGLAY  EVPVNW   LGT +ANEE++ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRPMRQWMLKITAYGdrlledldeldWPESLKDMQRNWIGRSEGAEVHFNIDGTDEKF  241
            V R+PMRQWMLKITAY++RLLEDL+E+DWPES+KDMQRNWIG+S GA+V F++ +TD  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  TVFTTRPDTLFGATYCVLAPEHALVAEITTAEQKEAVEAYINAVKMKSDLERTELAKEKT  301
            TVFTTRPDTLFGATY VLAPEHALV  ITT++Q EAV  Y     +KSDL RT+LAKEKT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAVNPVNGEKLPIWIADYVLATYGTGAVMAVPAHDERDYEFASVFNLPMKEVVK  361
            GV TG+YA+NPVNG  +P+WIADYVLA+YGTGA+MAVPAHDERD EFA  FNL +  V+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGDITKEVYTGDGAHVNSAFLDGLNKEEAIAKMIEWLEATSAGNQKVTYRLRDWLFSRQR  421
            GG++    +T DG H+NS FLDGL+K  AIAKM+EWLEA + GN++VTYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPVIHWEDGTMTAVKEEELPLVLPKTENIRPSGTGESPLANIDEWVNVVDPETGK  481
            YWGEPIP+IHWEDGT TAV E ELPLVLP T +IRPSGTGESPLAN+ +W++V   E G 
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT-REDGV  482

Query  482  KGRRETNTMPQWAGSCWYYLRYIDPNNSEALVDPEKVKQWLPVDIYIGGAEHAVLHLLYA  541
            KGRRETNTMPQWAGS WYYLRYIDP+N+E L D E +KQWLPVDIY+GGAEHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKVLYDIGVVPTKEPFQQLFNQGMILG------------------------------  571
            RFWHKVLYD+GVVPTKEPFQ+LFNQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---ENNEKMSKSKGNVVNPDDIVASHGADTLRLYEMFMGPLDASIAWSENGLDGARRFLD  628
               +   KMSKS  NVVNPDD+V   GADTLR+YEMFMGPLDASIAWSE+GL+G+R+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RVWRLFVQDNGELSEKITDAPNKELEKAYHQTVKKVTEDYAELRFNTAISQMMVFINDAY  688
            RV RL+       +  IT+  +  L+K Y++TVK VTE+  +++FNTAI+Q+MVF+N A 
Sbjct  663  RVYRLIT------TKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  689  KAETLPREYVEGFVKMIAPVAPHIGEELWSKL-GYNETITYASWPTFDESKLVEDEVEIV  747
            K + L  +Y  GFV++IAP APH+GEELW  L +  E+I+Y +WP++DESKLVE++VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  748  VQVMGKVRAKLTMSKDASKEEMEQLAL--EAIQDQIEG  783
            VQ+ GKV+AKL ++KD S+EE++++AL  E +Q +I G
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAG  814

239) leuS in NC_017195


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  916 bits (3469),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 560/837 (67%), Positives = 671/837 (81%), Gaps = 42/837 (5%)

Query  3    FQHKEIEKKWQTYWLENKTFATLDNNEKQKFYALDMFPYPSGAGLHVGHPEGYTATDILS  62
            ++H  IE KWQ++W +N TF T  +  K KFYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMKRMQGYDVLHPMGWDAFGLPAEQYALDTGNDPAVFTKQNIDNFRRQIQALGFSYDWDR  122
            R KR QG +VLHPMGWDAFGLPAEQYA+DTGNDPA FT +NI NF+RQI+ALGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EINTTDPEYYKWTQWIFLKLYEKGLAYVDEVPVNWCPALGTVLANEEVI-DGKSERGGHP  181
            E+NTTDP+YYKWTQWIF KLYEKGLAY  EVPVNW   LGT +ANEEV+ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRPMKQWMLKITAYAdrlledleeldWPESIKDMQRNWIGRSEGAHVHFAIDGHDDSF  241
            V R+PM+QWMLKITAYA+RLLEDLEE+DWPESIKDMQRNWIG+S GA+V F + + D  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  TVFTTRPDTLFGATYTVLAPEHALVENITTAEQKEAVEAYIKEIQSKSDLERTDLAKTKT  301
            TVFTTRPDTLFGATY+VLAPEHALV+ ITT++Q EAV  Y ++   KSDL RTDLAK KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAINPVNGEKLPIWIADYVLASYGTGAVMAVPGHDERDFEFAKTFGLPvkevvk  361
            GV TG+YAINPVNG  +P+WIADYVLASYGTGA+MAVP+HDERD EFAK F L +  V+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  ggnveeAAYTGDGEHVNSDFLNGLHKQEAIEKVIAWLEETKNGEKKVTYRLRDWLFSRQR  421
            GGNVEEAA+T DG H+NSDFL+GL+K  AI K++ WLE    G+ +VTYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPVIHWEDGTSTAVPEEELPLILPKTDEIKPSGTGESPLANIKEWVEVTDPETGK  481
            YWGEPIP+IHWEDGTSTAVPE ELPL+LP T +I+PSGTGESPLAN+ +W+EVT  E G 
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT-REDGV  482

Query  482  KGRRETNTMPQWAGSCWYFLRYIDPHNPDQLASPEKLEKWLPVDMYIGGAEHAVLHLLYA  541
            KGRRETNTMPQWAGS WY+LRYIDPHN ++LA  E L +WLPVD+Y+GGAEHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKFLYDIGVVPTKEPFQKLYNQGMILG------------------------------  571
            RFWHK LYD+GVVPTKEPFQKL+NQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---ENNEKMSKSKGNVVNPDEIVSSHGADTLRLYEMFMGPLDASIAWSESGLDGARRFLD  628
               +   KMSKS  NVVNPD++V   GADTLR+YEMFMGPLDASIAWSE GL+G+R+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RVWRLFVEENGELNGKIVEGAGETLERVYHETVMKVTDHYEGLRFNTGISQLMVFINEAY  688
            RV RL+   +      I E  + +L++VY+ETV  VT++ + ++FNT+I+QLMVF+N A 
Sbjct  663  RVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  689  KATELPKEYMEGFVKLLSPIAPHLAEELWEKLGHSG-TIAYEAWPVYDETKLVDDEVEIV  747
            K   L  +Y  GFV+L++P+APHL+EELW+ L  SG +I+Y +WP YDE+KLV+++VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  748  IQLNGKVKAKLQVPADATKEQLEQLAQADEKVKEQLEGKTIRKIIAVPGKLVNIVAN  804
            +Q++GKVKAKL V+ D ++E+L+++A A+EKV+ ++ GK I K+IAVP KLVNIV +
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

240) leuS in NC_000964


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  915 bits (3465),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 561/837 (68%), Positives = 669/837 (80%), Gaps = 42/837 (5%)

Query  3    FQHKEIEKKWQTYWLENKTFATLDNNEKQKFYALDMFPYPSGAGLHVGHPEGYTATDILS  62
            ++H  IE KWQ++W +N TF T  +  K KFYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMKRMQGYDVLHPMGWDAFGLPAEQYALDTGNDPAVFTKQNIDNFRRQIQALGFSYDWDR  122
            R KR QG +VLHPMGWDAFGLPAEQYA+DTGNDPA FT +NI NF+RQI+ALGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EINTTDPEYYKWTQWIFLKLYEKGLAYVDEVPVNWCPALGTVLANEEVI-DGKSERGGHP  181
            E+NTTDP+YYKWTQWIF KLYEKGLAY  EVPVNW   LGT +ANEEV+ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRPMKQWMLKITAYAdrlledleeldWPESIKDMQRNWIGRSEGAHVHFAIDGHDDSF  241
            V R+PM+QWMLKITAYA+RLLEDLEE+DWPESIKDMQRNWIG+S GA+V F + + D  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  TVFTTRPDTLFGATYTVLAPEHALVENITTAEQKEAVEAYIKEIQSKSDLERTDLAKTKT  301
            TVFTTRPDTLFGATY+VLAPEHALV+ ITT++Q EAV  Y ++   KSDL RTDLAK KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAINPVNGEKLPIWIADYVLASYGTGAVMAVPGHDERDFEFAKTFGLPvkevvk  361
            GV TG+YAINPVNG  +P+WIADYVLASYGTGA+MAVP+HDERD EFAK F L +  V+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  ggnveeAAYTGDGEHVNSDFLNGLHKQEAIEKVIAWLEETKNGEKKVTYRLRDWLFSRQR  421
            GGNVEEAA+T DG H+NSDFL+GL+K  AI K++ WLE    G+ +VTYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPVIHWEDGTSTAVPEEELPLILPKTDEIKPSGTGESPLANIKEWVEVTDPETGK  481
            YWGEPIP+IHWEDGTSTAVPE ELPL+LP T +I+PSGTGESPLAN+ +W+EVT  E G 
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT-REDGV  482

Query  482  KGRRETNTMPQWAGSCWYFLRYIDPHNPDQLASPEKLEKWLPVDMYIGGAEHAVLHLLYA  541
            KGRRETNTMPQWAGS WY+LRYIDPHN ++LA  E L +WLPVD+Y+GGAEHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKFLYDIGVVPTKEPFQKLYNQGMILG------------------------------  571
            RFWHK LYD+GVVPTKEPFQKL+NQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---ENNEKMSKSKGNVVNPDEIVASHGADTLRLYEMFMGPLDASIAWSESGLDGARRFLD  628
               +   KMSKS  NVVNPD++V   GADTLR+YEMFMGPLDASIAWSE GL+G+R+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RVWRLFIEDSGELNGKIVEGAGETLERVYHETVMKVTDHYEGLRFNTGISQLMVFINEAY  688
            RV RL+          I E  + +L++VY+ETV  VT++ + ++FNT+I+QLMVF+N A 
Sbjct  663  RVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  689  KATELPKEYMEGFVKLLSPVAPHLAEELWEKLGHSG-TIAYEAWPVYDETKLVDDEVEIV  747
            K   L  +Y  GFV+L++P APHL+EELW+ L  SG +I+Y +WP YDE+KLV+++VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  748  VQLNGKVKAKLQVPADATKEQLEQLAQADEKVKEQLEGKTIRKIIAVPGKLVNIVAN  804
            VQ++GKVKAKL V+ D ++E+L+++A A+EKV+ ++ GK I K+IAVP KLVNIV +
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

241) leuS in NC_020507


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  915 bits (3465),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 561/837 (68%), Positives = 669/837 (80%), Gaps = 42/837 (5%)

Query  3    FQHKEIEKKWQTYWLENKTFATLDNNEKQKFYALDMFPYPSGAGLHVGHPEGYTATDILS  62
            ++H  IE KWQ++W +N TF T  +  K KFYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMKRMQGYDVLHPMGWDAFGLPAEQYALDTGNDPAVFTKQNIDNFRRQIQALGFSYDWDR  122
            R KR QG +VLHPMGWDAFGLPAEQYA+DTGNDPA FT +NI NF+RQI+ALGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EINTTDPEYYKWTQWIFLKLYEKGLAYVDEVPVNWCPALGTVLANEEVI-DGKSERGGHP  181
            E+NTTDP+YYKWTQWIF KLYEKGLAY  EVPVNW   LGT +ANEEV+ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRPMKQWMLKITAYAdrlledleeldWPESIKDMQRNWIGRSEGAHVHFAIDGHDDSF  241
            V R+PM+QWMLKITAYA+RLLEDLEE+DWPESIKDMQRNWIG+S GA+V F + + D  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  TVFTTRPDTLFGATYTVLAPEHALVENITTAEQKEAVEAYIKEIQSKSDLERTDLAKTKT  301
            TVFTTRPDTLFGATY+VLAPEHALV+ ITT++Q EAV  Y ++   KSDL RTDLAK KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAINPVNGEKLPIWIADYVLASYGTGAVMAVPGHDERDFEFAKTFGLPvkevvk  361
            GV TG+YAINPVNG  +P+WIADYVLASYGTGA+MAVP+HDERD EFAK F L +  V+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  ggnveeAAYTGDGEHVNSDFLNGLHKQEAIEKVIAWLEETKNGEKKVTYRLRDWLFSRQR  421
            GGNVEEAA+T DG H+NSDFL+GL+K  AI K++ WLE    G+ +VTYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPVIHWEDGTSTAVPEEELPLILPKTDEIKPSGTGESPLANIKEWVEVTDPETGK  481
            YWGEPIP+IHWEDGTSTAVPE ELPL+LP T +I+PSGTGESPLAN+ +W+EVT  E G 
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT-REDGV  482

Query  482  KGRRETNTMPQWAGSCWYFLRYIDPHNPDQLASPEKLEKWLPVDMYIGGAEHAVLHLLYA  541
            KGRRETNTMPQWAGS WY+LRYIDPHN ++LA  E L +WLPVD+Y+GGAEHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKFLYDIGVVPTKEPFQKLYNQGMILG------------------------------  571
            RFWHK LYD+GVVPTKEPFQKL+NQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---ENNEKMSKSKGNVVNPDEIVASHGADTLRLYEMFMGPLDASIAWSESGLDGARRFLD  628
               +   KMSKS  NVVNPD++V   GADTLR+YEMFMGPLDASIAWSE GL+G+R+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RVWRLFIEDSGELNGKIVEGAGETLERVYHETVMKVTDHYEGLRFNTGISQLMVFINEAY  688
            RV RL+          I E  + +L++VY+ETV  VT++ + ++FNT+I+QLMVF+N A 
Sbjct  663  RVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  689  KATELPKEYMEGFVKLLSPVAPHLAEELWEKLGHSG-TIAYEAWPVYDETKLVDDEVEIV  747
            K   L  +Y  GFV+L++P APHL+EELW+ L  SG +I+Y +WP YDE+KLV+++VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  748  VQLNGKVKAKLQVPADATKEQLEQLAQADEKVKEQLEGKTIRKIIAVPGKLVNIVAN  804
            VQ++GKVKAKL V+ D ++E+L+++A A+EKV+ ++ GK I K+IAVP KLVNIV +
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

242) leuS in NC_014976


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  915 bits (3467),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 561/837 (68%), Positives = 670/837 (81%), Gaps = 42/837 (5%)

Query  3    FQHKEIEKKWQTYWLENKTFATLDNNEKQKFYALDMFPYPSGAGLHVGHPEGYTATDILS  62
            ++H  IE KWQ++W +N TF T  +  K KFYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMKRMQGYDVLHPMGWDAFGLPAEQYALDTGNDPAVFTKQNIDNFRRQIQALGFSYDWDR  122
            R KR QG +VLHPMGWDAFGLPAEQYA+DTGNDPA FT +NI NF+RQI+ALGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EINTTDPEYYKWTQWIFLKLYEKGLAYVDEVPVNWCPALGTVLANEEVI-DGKSERGGHP  181
            E+NTTDP+YYKWTQWIF KLYEKGLAY  EVPVNW   LGT +ANEEV+ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRPMKQWMLKITAYAdrlledleeldWPESIKDMQRNWIGRSEGAHVHFAIDGHDDSF  241
            V R+PM+QWMLKITAYA+RLLEDLEE+DWPESIKDMQRNWIG+S GA+V F + + D  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  TVFTTRPDTLFGATYTVLAPEHALVENITTAEQKEAVEAYIKEIQSKSDLERTDLAKTKT  301
            TVFTTRPDTLFGATY+VLAPEHALV+ ITT++Q EAV  Y ++   KSDL RTDLAK KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAINPVNGEKLPIWIADYVLASYGTGAVMAVPGHDERDFEFAKTFGLPvkevvk  361
            GV TG+YAINPVNG  +P+WIADYVLASYGTGA+MAVP+HDERD EFAK F L +  V+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  ggnveeAAYTGDGEHVNSDFLNGLHKQEAIEKVIAWLEETKNGEKKVTYRLRDWLFSRQR  421
            GGNVEEAA+T DG H+NSDFL+GL+K  AI K++ WLE    G+ +VTYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPVIHWEDGTSTAVPEEELPLILPKTDEIKPSGTGESPLANIKEWVEVTDPETGK  481
            YWGEPIP+IHWEDGTSTAVPE ELPL+LP T +I+PSGTGESPLAN+ +W+EVT  E G 
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT-REDGV  482

Query  482  KGRRETNTMPQWAGSCWYFLRYIDPHNPDQLASPEKLEKWLPVDMYIGGAEHAVLHLLYA  541
            KGRRETNTMPQWAGS WY+LRYIDPHN ++LA  E L +WLPVD+Y+GGAEHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKFLYDIGVVPTKEPFQKLYNQGMILG------------------------------  571
            RFWHK LYD+GVVPTKEPFQKL+NQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---ENNEKMSKSKGNVVNPDEIVSSHGADTLRLYEMFMGPLDASIAWSESGLDGARRFLD  628
               +   KMSKS  NVVNPD++V   GADTLR+YEMFMGPLDASIAWSE GL+G+R+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RVWRLFVEENGELNGKIVEGAGETLERVYHETVMKVTDHYEGLRFNTGISQLMVFINEAY  688
            RV RL+   +      I E  + +L++VY+ETV  VT++ + ++FNT+I+QLMVF+N A 
Sbjct  663  RVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  689  KATELPKEYMEGFVKLLSPVAPHLAEELWEKLGHSG-TIAYEAWPVYDETKLVDDEVEIV  747
            K   L  +Y  GFV+L++P APHL+EELW+ L  SG +I+Y +WP YDE+KLV+++VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  748  VQLNGKVKAKLQVPADATKEQLEQLAQADEKVKEQLEGKTIRKIIAVPGKLVNIVAN  804
            VQ++GKVKAKL V+ D ++E+L+++A A+EKV+ ++ GK I K+IAVP KLVNIV +
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

243) A7A1_1644 in NC_019896


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  915 bits (3467),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 561/837 (68%), Positives = 670/837 (81%), Gaps = 42/837 (5%)

Query  3    FQHKEIEKKWQTYWLENKTFATLDNNEKQKFYALDMFPYPSGAGLHVGHPEGYTATDILS  62
            ++H  IE KWQ++W +N TF T  +  K KFYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMKRMQGYDVLHPMGWDAFGLPAEQYALDTGNDPAVFTKQNIDNFRRQIQALGFSYDWDR  122
            R KR QG +VLHPMGWDAFGLPAEQYA+DTGNDPA FT +NI NF+RQI+ALGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EINTTDPEYYKWTQWIFLKLYEKGLAYVDEVPVNWCPALGTVLANEEVI-DGKSERGGHP  181
            E+NTTDP+YYKWTQWIF KLYEKGLAY  EVPVNW   LGT +ANEEV+ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRPMKQWMLKITAYAdrlledleeldWPESIKDMQRNWIGRSEGAHVHFAIDGHDDSF  241
            V R+PM+QWMLKITAYA+RLLEDLEE+DWPESIKDMQRNWIG+S GA+V F + + D  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  TVFTTRPDTLFGATYTVLAPEHALVENITTAEQKEAVEAYIKEIQSKSDLERTDLAKTKT  301
            TVFTTRPDTLFGATY+VLAPEHALV+ ITT++Q EAV  Y ++   KSDL RTDLAK KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAINPVNGEKLPIWIADYVLASYGTGAVMAVPGHDERDFEFAKTFGLPvkevvk  361
            GV TG+YAINPVNG  +P+WIADYVLASYGTGA+MAVP+HDERD EFAK F L +  V+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  ggnveeAAYTGDGEHVNSDFLNGLHKQEAIEKVIAWLEETKNGEKKVTYRLRDWLFSRQR  421
            GGNVEEAA+T DG H+NSDFL+GL+K  AI K++ WLE    G+ +VTYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPVIHWEDGTSTAVPEEELPLILPKTDEIKPSGTGESPLANIKEWVEVTDPETGK  481
            YWGEPIP+IHWEDGTSTAVPE ELPL+LP T +I+PSGTGESPLAN+ +W+EVT  E G 
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT-REDGV  482

Query  482  KGRRETNTMPQWAGSCWYFLRYIDPHNPDQLASPEKLEKWLPVDMYIGGAEHAVLHLLYA  541
            KGRRETNTMPQWAGS WY+LRYIDPHN ++LA  E L +WLPVD+Y+GGAEHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKFLYDIGVVPTKEPFQKLYNQGMILG------------------------------  571
            RFWHK LYD+GVVPTKEPFQKL+NQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---ENNEKMSKSKGNVVNPDEIVSSHGADTLRLYEMFMGPLDASIAWSESGLDGARRFLD  628
               +   KMSKS  NVVNPD++V   GADTLR+YEMFMGPLDASIAWSE GL+G+R+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RVWRLFVEENGELNGKIVEGAGETLERVYHETVMKVTDHYEGLRFNTGISQLMVFINEAY  688
            RV RL+   +      I E  + +L++VY+ETV  VT++ + ++FNT+I+QLMVF+N A 
Sbjct  663  RVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  689  KATELPKEYMEGFVKLLSPVAPHLAEELWEKLGHSG-TIAYEAWPVYDETKLVDDEVEIV  747
            K   L  +Y  GFV+L++P APHL+EELW+ L  SG +I+Y +WP YDE+KLV+++VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  748  VQLNGKVKAKLQVPADATKEQLEQLAQADEKVKEQLEGKTIRKIIAVPGKLVNIVAN  804
            VQ++GKVKAKL V+ D ++E+L+++A A+EKV+ ++ GK I K+IAVP KLVNIV +
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

244) leuS in NC_018520


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  915 bits (3465),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 561/837 (68%), Positives = 669/837 (80%), Gaps = 42/837 (5%)

Query  3    FQHKEIEKKWQTYWLENKTFATLDNNEKQKFYALDMFPYPSGAGLHVGHPEGYTATDILS  62
            ++H  IE KWQ++W +N TF T  +  K KFYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMKRMQGYDVLHPMGWDAFGLPAEQYALDTGNDPAVFTKQNIDNFRRQIQALGFSYDWDR  122
            R KR QG +VLHPMGWDAFGLPAEQYA+DTGNDPA FT +NI NF+RQI+ALGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EINTTDPEYYKWTQWIFLKLYEKGLAYVDEVPVNWCPALGTVLANEEVI-DGKSERGGHP  181
            E+NTTDP+YYKWTQWIF KLYEKGLAY  EVPVNW   LGT +ANEEV+ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRPMKQWMLKITAYAdrlledleeldWPESIKDMQRNWIGRSEGAHVHFAIDGHDDSF  241
            V R+PM+QWMLKITAYA+RLLEDLEE+DWPESIKDMQRNWIG+S GA+V F + + D  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  TVFTTRPDTLFGATYTVLAPEHALVENITTAEQKEAVEAYIKEIQSKSDLERTDLAKTKT  301
            TVFTTRPDTLFGATY+VLAPEHALV+ ITT++Q EAV  Y ++   KSDL RTDLAK KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAINPVNGEKLPIWIADYVLASYGTGAVMAVPGHDERDFEFAKTFGLPvkevvk  361
            GV TG+YAINPVNG  +P+WIADYVLASYGTGA+MAVP+HDERD EFAK F L +  V+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  ggnveeAAYTGDGEHVNSDFLNGLHKQEAIEKVIAWLEETKNGEKKVTYRLRDWLFSRQR  421
            GGNVEEAA+T DG H+NSDFL+GL+K  AI K++ WLE    G+ +VTYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPVIHWEDGTSTAVPEEELPLILPKTDEIKPSGTGESPLANIKEWVEVTDPETGK  481
            YWGEPIP+IHWEDGTSTAVPE ELPL+LP T +I+PSGTGESPLAN+ +W+EVT  E G 
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT-REDGV  482

Query  482  KGRRETNTMPQWAGSCWYFLRYIDPHNPDQLASPEKLEKWLPVDMYIGGAEHAVLHLLYA  541
            KGRRETNTMPQWAGS WY+LRYIDPHN ++LA  E L +WLPVD+Y+GGAEHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKFLYDIGVVPTKEPFQKLYNQGMILG------------------------------  571
            RFWHK LYD+GVVPTKEPFQKL+NQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---ENNEKMSKSKGNVVNPDEIVASHGADTLRLYEMFMGPLDASIAWSESGLDGARRFLD  628
               +   KMSKS  NVVNPD++V   GADTLR+YEMFMGPLDASIAWSE GL+G+R+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RVWRLFIEDSGELNGKIVEGAGETLERVYHETVMKVTDHYEGLRFNTGISQLMVFINEAY  688
            RV RL+          I E  + +L++VY+ETV  VT++ + ++FNT+I+QLMVF+N A 
Sbjct  663  RVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  689  KATELPKEYMEGFVKLLSPVAPHLAEELWEKLGHSG-TIAYEAWPVYDETKLVDDEVEIV  747
            K   L  +Y  GFV+L++P APHL+EELW+ L  SG +I+Y +WP YDE+KLV+++VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  748  VQLNGKVKAKLQVPADATKEQLEQLAQADEKVKEQLEGKTIRKIIAVPGKLVNIVAN  804
            VQ++GKVKAKL V+ D ++E+L+++A A+EKV+ ++ GK I K+IAVP KLVNIV +
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

245) leuS in NC_020832


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  914 bits (3462),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 560/837 (67%), Positives = 669/837 (80%), Gaps = 42/837 (5%)

Query  3    FQHKEIEKKWQTYWLENKTFATLDNNEKQKFYALDMFPYPSGAGLHVGHPEGYTATDILS  62
            ++H  IE KWQ++W +N TF T  +  K KFYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMKRMQGYDVLHPMGWDAFGLPAEQYALDTGNDPAVFTKQNIDNFRRQIQALGFSYDWDR  122
            R KR QG +VLHPMGWDAFGLPAEQYA+DTGNDPA FT +NI NF+RQI+ALGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EINTTDPEYYKWTQWIFLKLYEKGLAYVDEVPVNWCPALGTVLANEEVI-DGKSERGGHP  181
            E+NTTDP+YYKWTQWIF KLYEKGLAY  EVPVNW   LGT +ANEEV+ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRPMKQWMLKITAYAdrlledleeldWPESIKDMQRNWIGRSEGAHVHFAIDGHDDSF  241
            V R+PM+QWMLKITAYA+RLLEDLEE+DWPESIKDMQRNWIG+S GA+V F + + D  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  TVFTTRPDTLFGATYTVLAPEHALVENITTAEQKEAVEAYIKEIQSKSDLERTDLAKTKT  301
            TVFTTRPDTLFGATY+VLAPEHALV+ ITT++Q EAV  Y ++   KSDL RTDLAK KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAINPVNGEKLPIWIADYVLASYGTGAVMAVPGHDERDFEFAKTFGLPvkevvk  361
            GV TG+YAINPVNG  +P+WIADYVLASYGTGA+MAVP+HDERD EFAK F L +  V+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  ggnveeAAYIGDGEHVNSDFLNGLHKQEAIEKVIAWLEETKNGEKKVTYRLRDWLFSRQR  421
            GGNVEEAA+  DG H+NSDFL+GL+K  AI K++ WLE    G+ +VTYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPVIHWEDGTSTAVPEEELPLILPKTDEIKPSGTGESPLANIKEWVEVTDPETGK  481
            YWGEPIP+IHWEDGTSTAVPE ELPL+LP T +I+PSGTGESPLAN+ +W+EVT  E G 
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT-REDGV  482

Query  482  KGRRETNTMPQWAGSCWYFLRYIDPHNPDQLASPEKLEKWLPVDMYIGGAEHAVLHLLYA  541
            KGRRETNTMPQWAGS WY+LRYIDPHN ++LA  E L +WLPVD+Y+GGAEHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKFLYDIGVVPTKEPFQKLYNQGMILG------------------------------  571
            RFWHK LYD+GVVPTKEPFQKL+NQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---ENNEKMSKSKGNVVNPDEIVSSHGADTLRLYEMFMGPLDASIAWSESGLDGARRFLD  628
               +   KMSKS  NVVNPD++V   GADTLR+YEMFMGPLDASIAWSE GL+G+R+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RVWRLFIEDSGELNGKIVEGAGETLERVYHETVMKVTDHYEGLRFNTGISQLMVFINEAY  688
            RV RL+          I E  + +L++VY+ETV  VT++ + ++FNT+I+QLMVF+N A 
Sbjct  663  RVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  689  KASELPKEYMEGFVKLLSPIAPHLAEELWEKLGHSG-TIAYEAWPVYDETKLVDDEVEIV  747
            K   L  +Y  GFV+L++P+APHL+EELW+ L  SG +I+Y +WP YDE+KLV+++VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  748  VQLNGKVKAKLQVPADATKEQLEQLAQADEKVKEQLEGKTIRKIIAVPGKLVNIVAN  804
            VQ++GKVKAKL V+ D ++E+L+++A A+EKV+ ++ GK I K+IAVP KLVNIV +
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

246) leuS in NC_017196


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  914 bits (3461),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 560/837 (67%), Positives = 668/837 (80%), Gaps = 42/837 (5%)

Query  3    FQHKEIEKKWQTYWLENKTFATLDNNEKQKFYALDMFPYPSGAGLHVGHPEGYTATDILS  62
            ++H  IE KWQ++W +N TF T  +  K KFYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMKRMQGYDVLHPMGWDAFGLPAEQYALDTGNDPAVFTKQNIDNFRRQIQALGFSYDWDR  122
            R KR QG +VLHPMGWDAFGLPAEQYA+DTGNDPA FT +NI NF+RQI+ALGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EINTTDPEYYKWTQWIFLKLYEKGLAYVDEVPVNWCPALGTVLANEEVI-DGKSERGGHP  181
            E+NTTDP+YYKWTQWIF KLYEKGLAY  EVPVNW   LGT +ANEEV+ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRPMKQWMLKITAYAdrlledleeldWPESIKDMQRNWIGRSEGAHVHFAIDGHDDSF  241
            V R+PM+QWMLKITAYA+RLLEDLEE+DWPESIKDMQRNWIG+S GA+V F + + D  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  TVFTTRPDTLFGATYTVLAPEHALVENITTAEQKEAVEAYIKEIQSKSDLERTDLAKTKT  301
            TVFTTRPDTLFGATY+VLAPEHALV+ ITT++Q EAV  Y ++   KSDL RTDLAK KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAINPVNGEKLPIWIADYVLASYGTGAVMAVPGHDERDFEFAKTFGLPvkevvk  361
            GV TG+YAINPVNG  +P+WIADYVLASYGTGA+MAVP+HDERD EFAK F L +  V+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  ggnveeAAYTGDGEHVNSDFLNGLHKQEAIEKVIAWLEETKNGEKKVTYRLRDWLFSRQR  421
            GGNVEEAA+T DG H+NSDFL+GL+K  AI K++ WLE    G+ +VTYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPVIHWEDGTSTAVPEEELPLILPKTDEIKPSGTGESPLANIKEWVEVTDPETGK  481
            YWGEPIP+IHWEDGTSTAVPE ELPL+LP T +I+PSGTGESPLAN+ +W+EVT  E G 
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT-REDGV  482

Query  482  KGRRETNTMPQWAGSCWYFLRYIDPHNPDQLASPEKLEKWLPVDMYIGGAEHAVLHLLYA  541
            KGRRETNTMPQWAGS WY+LRYIDPHN ++LA  E L +WLPVD+Y+GGAEHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKFLYDIGVVPTKEPFQKLYNQGMILG------------------------------  571
            RFWHK LYD+GVVPTKEPFQKL+NQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---ENNEKMSKSKGNVVNPDEIVASHGADTLRLYEMFMGPLDASIAWSESGLDGARRFLD  628
               +   KMSKS  NVVNPD++V   GADTLR+YEMFMGPLDASIAWSE GL+G+R+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RVWRLFIEDSGELNGKIVEGAGETLERVYHETVMKVTDHYEGLRFNTGISQLMVFINEAY  688
            RV RL+          I E  + +L++VY+ETV  VT++ + ++FNT+I+QLMVF+N A 
Sbjct  663  RVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  689  KATELPKEYMEGFVKLLSPVAPHLAEELWEKLGHSG-TIAYEAWPVYDETKLVDDEVEIV  747
            K   L  +Y  GFV+L++P APHL+EELW+ L  SG +I+Y +WP YDE+KLV+++VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  748  VQLNGKVKAKLQVPADATKEQLEQLAQADEKVKEQLEGKTIRKIIAVPGTLVNIVAN  804
            VQ++GKVKAKL V+ D ++E+L+++A A+EKV+ ++ GK I K+IAVP  LVNIV +
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

247) leuS in NC_020244


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  914 bits (3462),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 560/837 (67%), Positives = 669/837 (80%), Gaps = 42/837 (5%)

Query  3    FQHKEIEKKWQTYWLENKTFATLDNNEKQKFYALDMFPYPSGAGLHVGHPEGYTATDILS  62
            ++H  IE KWQ++W +N TF T  +  K KFYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMKRMQGYDVLHPMGWDAFGLPAEQYALDTGNDPAVFTKQNIDNFRRQIQALGFSYDWDR  122
            R KR QG +VLHPMGWDAFGLPAEQYA+DTGNDPA FT +NI NF+RQI+ALGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EINTTDPEYYKWTQWIFLKLYEKGLAYVDEVPVNWCPALGTVLANEEVI-DGKSERGGHP  181
            E+NTTDP+YYKWTQWIF KLYEKGLAY  EVPVNW   LGT +ANEEV+ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRPMKQWMLKITAYAdrlledleeldWPESIKDMQRNWIGRSEGAHVHFAIDGHDDSF  241
            V R+PM+QWMLKITAYA+RLLEDLEE+DWPESIKDMQRNWIG+S GA+V F + + D  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  TVFTTRPDTLFGATYTVLAPEHALVENITTAEQKEAVEAYIKEIQSKSDLERTDLAKTKT  301
            TVFTTRPDTLFGATY+VLAPEHALV+ ITT++Q EAV  Y ++   KSDL RTDLAK KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAINPVNGEKLPIWIADYVLASYGTGAVMAVPGHDERDFEFAKTFGLPvkevvk  361
            GV TG+YAINPVNG  +P+WIADYVLASYGTGA+MAVP+HDERD EFAK F L +  V+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  ggnveeAAYIGDGEHVNSDFLNGLHKQEAIEKVIAWLEETKNGEKKVTYRLRDWLFSRQR  421
            GGNVEEAA+  DG H+NSDFL+GL+K  AI K++ WLE    G+ +VTYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPVIHWEDGTSTAVPEEELPLILPKTDEIKPSGTGESPLANIKEWVEVTDPETGK  481
            YWGEPIP+IHWEDGTSTAVPE ELPL+LP T +I+PSGTGESPLAN+ +W+EVT  E G 
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT-REDGV  482

Query  482  KGRRETNTMPQWAGSCWYFLRYIDPHNPDQLASPEKLEKWLPVDMYIGGAEHAVLHLLYA  541
            KGRRETNTMPQWAGS WY+LRYIDPHN ++LA  E L +WLPVD+Y+GGAEHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKFLYDIGVVPTKEPFQKLYNQGMILG------------------------------  571
            RFWHK LYD+GVVPTKEPFQKL+NQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---ENNEKMSKSKGNVVNPDEIVSSHGADTLRLYEMFMGPLDASIAWSESGLDGARRFLD  628
               +   KMSKS  NVVNPD++V   GADTLR+YEMFMGPLDASIAWSE GL+G+R+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RVWRLFIEDSGELNGKIVEGAGETLERVYHETVMKVTDHYEGLRFNTGISQLMVFINEAY  688
            RV RL+          I E  + +L++VY+ETV  VT++ + ++FNT+I+QLMVF+N A 
Sbjct  663  RVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  689  KASELPKEYMEGFVKLLSPIAPHLAEELWEKLGHSG-TIAYEAWPVYDETKLVDDEVEIV  747
            K   L  +Y  GFV+L++P+APHL+EELW+ L  SG +I+Y +WP YDE+KLV+++VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  748  VQLNGKVKAKLQVPADATKEQLEQLAQADEKVKEQLEGKTIRKIIAVPGKLVNIVAN  804
            VQ++GKVKAKL V+ D ++E+L+++A A+EKV+ ++ GK I K+IAVP KLVNIV +
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

248) leuS in NC_011567


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  913 bits (3460),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 563/838 (68%), Positives = 673/838 (81%), Gaps = 43/838 (5%)

Query  3    FNHREIEKKWQKYWEENKTFKTTEDDGKRKFYALDMFPYPSGAGLHVGHPEGYTATDILA  62
            ++H  IE KWQ +W +N TFKT  D +K KFYALDMFPYPSGAGLHVGHPEGYTATDIL+
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMKRMQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTEKNINNFRRQIKSLGFSYDWDR  122
            R KR QG NVLHPMGWDAFGLPAEQYA+DTGNDPAEFT  NI NF+RQI++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVNTTDPNYYKWTQWIFLKLYEKGLAYMDEVPVNWCPALGTVLANEEVI-DGKSERGGHP  181
            EVNTTDPNYYKWTQWIF KLYEKGLAY  EVPVNW   LGT +ANEEV+ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VIRKPMKQWMLRITAYAdrlledleeldWPESIKEMQRNWIGRSEGANIHFQVDGHDETF  241
            V+RKPM+QWML+ITAYA+RLLEDLEE+DWPESIK+MQRNWIG+S GAN+ F+V + D  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  TVFTTRPDTLFGATYAVLAPEHPLVEKITTPEQKEAVEAYLKQIQSKSDLERTDLAKEKT  301
            TVFTTRPDTLFGATYAVLAPEH+LV+ ITT++Q EAV  Y +Q   KSDL RTDLAKEKT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAINPANGEKLPIWIADYVLMSYGTGAIMAVPAHDERDYEFAKKFNLPIKQVVA  361
            GV TG+YAINP NG  +P+WIADYVL SYGTGAIMAVPAHDERD EFAK+FNL I  V+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGDISKEAYTGDGEHINSDFLNGLNKEEATKKMIEWLEANGKGEKKVSYRLRDWLFSRQR  421
            GG++   A+T DG HINSDFL+GL+K  A  KM+EWLEA+G G+ +V+YRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPIIHWEDGTMTpvpeeelplvlpKTDEIKPSGTGESPLANIEEWVSVVDPKTGK  481
            YWGEPIPIIHWEDGT T+VPE ELPLVLP T +I+PSGTGESPLAN+ +W+ V     G 
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT-REDGV  482

Query  482  KGRRETNTMPQWAGSCWYYLRYIDPHNDKQLADPEKLEKWLPVDIYIGGAEHAVLHLLYA  541
            KGRRETNTMPQWAGS WYYLRYIDPHN  +LAD E L +WLPVDIY+GGAEHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKFLYDIGVVPTKEPFQKLFNQGMILG------------------------------  571
            RFWHK LYD+GVVPTKEPFQKLFNQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---ENNEKMSKSKGNVVNPDDIVESHGADTLRLYEMFMGPLEASIAWSTKGLDGARRFLD  628
               +   KMSKS  NVVNPDD+VE  GADTLR+YEMFMGPL+ASIAWS  GL+G+R+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RVWRLFVEENGELNPKIVDNPETDTLERVYHQTVKKVTEDYEALRFNTAISQLMVFINEA  688
            RV RL       +  K + + ++++L++VY++TVK VTE+ + ++FNTAI+QLMVF+N A
Sbjct  663  RVYRL-------ITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAA  715

Query  689  YKAPILPKAYMEGFVKLLSPVCPHIAEELWEKL-GYSNTIAYEAWPAYDEAKLVEDEVEI  747
             K   L   Y  GFV+L++P  PH++EELW+ L + +++I+Y +WP+YDE+KLVE++VEI
Sbjct  716  NKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEI  775

Query  748  VIQVNGKVRAKLHVPADATKEQLEQLAMEDEKIKEQIEGKTVRKVIAVPGKLVNIVAN  805
            V+Q++GKV+AKL V+ D ++E+L+++A+ +EK++ +I GK + KVIAVP KLVNIV +
Sbjct  776  VVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

249) leuS in NC_019842


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  910 bits (3447),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 562/837 (68%), Positives = 671/837 (81%), Gaps = 42/837 (5%)

Query  3    FQHEKIEKKWQNYWLDHKTFAVSEENDKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  62
            ++H  IE KWQ +W D+ TF  + +  KPKFYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMRRMQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTKQNIDNFRRQIQSLGFSYDWDR  122
            R +R QG NVLHPMGWDAFGLPAEQYA+DTGNDPAEFT +NI NF+RQI++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EINTTDPDYYKWTQWIFTKLYEKGLAYVDEVPVNWCPALGTVLANEEVI-DGKSERGGHP  181
            E+NTTDP+YYKWTQWIFTKLYEKGLAY  EVPVNW   LGT +ANEEV+ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRPMRQWMLKITAYAdrlledledldWPESIKDMQRNWIGRSEGANVHFAIdgtddtf  241
            V R+PMRQWMLKITAYA+RLLEDLE++DWPESIKDMQRNWIG+S GANV F + +TD  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  tvfttrpdtLFGAAYAVLAPEHELVEAITTPEQKEAVDAYVKEVQAKSDLERTDLAKTKT  301
            TVFTTRPDTLFGA+YAVLAPEH LV+AITT++Q EAV  Y ++   KSDL RTDLAK KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAVNPANGEKLPIWIADYVLASYGTGAVMAVPAHDERDFEFAKVFSLPVKEVVK  361
            GV TG+YA+NP NG  +P+WIADYVLASYGTGA+MAVPAHDERD EFAK F+L +  V+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGNTEEEAYTGDGEHVNSGFLNGLNKAEAIEKMIAWLEETKNGEKKVTYRLRDWLFSRQR  421
            GGN EE A+T DG H+NS+FL+GL+KA AI KM+ WLE    G+ +VTYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPVIHWEDGTSTAVPAEELPLILPKTDEIKPSGTGESPLANIKEWVEVTDPETGK  481
            YWGEPIP+IHWEDGTSTAVP  ELPL+LP T +I+PSGTGESPLAN+ +W+EVT  E G 
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT-REDGV  482

Query  482  KGRRETNTMPQWAGSCWYFLRFIDPKNPDQLASPEKLDKWLPVDIYIGGAEHAVLHLLYA  541
            KGRRETNTMPQWAGS WY+LR+IDP N ++LA  E L +WLPVDIY+GGAEHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKFLYDIGVVPTKEPFQKLYNQGMILG------------------------------  571
            RFWHK LYD+GVVPTKEPFQKL+NQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---ENNEKMSKSRGNVVNPDEIVASHGADTLRLYEMFMGPLDASIAWSESGLDGARRFLD  628
               +   KMSKS  NVVNPD++V   GADTLR+YEMFMGPLDASIAWSE GL+G+R+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RVWRLFIEENGELTGKVTEGAGETLERVYHETVMKVTENFEALRFNTGISQLMVFINEAY  688
            RV RL+       T  +TE  + +L++VY+ETV  VTE+ + ++FNT+I+QLMVF+N A 
Sbjct  663  RVYRLIT------TKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  689  KANELPREYIEGFVKLLSPIAPHLAEELWEKLGHEG-SIAYEAWPAYDESKLVDDEVEIV  747
            K + L  +Y  GFV+L++P+APHL+EELW+ L   G SI+Y +WP+YDESKLV+++VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  748  VQLNGKVKAKLMVPADADKAALEQLAQADEKVKEQLEGKTIRKIIAVPGKLVNIVAN  804
            VQ++GKVKAKL+V+ D  +  L+++A A+EKV+ ++ GK I K+IAVP KLVNIV +
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

250) leuS in NC_006270


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  910 bits (3448),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 565/837 (68%), Positives = 669/837 (80%), Gaps = 42/837 (5%)

Query  3    FDHQTIEKKWQDYWLKNKTFATREDKSKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  62
            +DH +IE KWQ +W  N TF T  D SKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMKRMQGYNVLHPMGWDAFGLPAEQYALDTGNDPAVFTEQNIDNFRRQIRALGFSYDWDR  122
            R KR QG NVLHPMGWDAFGLPAEQYA+DTGNDPA FT +NI NF+RQI ALGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVNTTDPDYYKWTQWIFLKLYEKGLAYVDEVPVNWCPALGTVLANEEVI-DGKSERGGHP  181
            EVNTTDP+YYKWTQWIF KLYEKGLAY  EVPVNW   LGT +ANEEV+ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRPMKQWMLKITAYAdrlledleeldWPESIKEMQRNWIGRSEGAHVHFAVDGTNETF  241
            V R+PM+QWMLKITAYA+RLLEDLEE+DWPESIK+MQRNWIG+S GA+V F V +T+  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  TVFTTRPDTLFGATYAVLAPEHDLVQKITTPEQKDAVNAYIEEVQSKSDLERTDLAKTKT  301
            TVFTTRPDTLFGATYAVLAPEH LV+ ITT++Q +AV  Y  +   KSDL RTDLAK KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAVNPANGEKIPVWIADYVLATYGTGAVMAVPAHDERDHEFASAFGLPIKEVVK  361
            GV TG+YA+NP NG  +PVWIADYVLA+YGTGA+MAVPAHDERD EFA  F L I  V+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGDVEKEAYTGDGEHIHSDFLNGLDKAAAIEKMIQWLEENGKGEKKVTYRLRDWLFSRQR  421
            GG+VE  A+T DG HI+SDFL+GLDKA+AI KM++WLE +G G+ +VTYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPIIHWEDGTSTPVpeeelplilpKTSEIKPSGTGESPLANIKEWVEVTDPETGK  481
            YWGEPIPIIHWEDGTST+VPE ELPL+LP T +I+PSGTGESPLAN+ +W+EVT  E G 
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT-REDGV  482

Query  482  KGRRETNTMPQWAGSCWYFLRYIDPKNPNELASPEKLKEWLPVDMYIGGAEHAVLHLLYA  541
            KGRRETNTMPQWAGS WY+LRYIDP N + LA  E LK+WLPVD+Y+GGAEHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKFLYDIGVVPTKEPFKQLYNQGMILG------------------------------  571
            RFWHK LYD+GVVPTKEPF++L+NQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---ENNEKMSKSKGNVVNPDEIVETHGADTLRLYEMFMGPLDASIAWSTTGLDGARRFLD  628
               +   KMSKS  NVVNPD++VE  GADTLR+YEMFMGPLDASIAWS  GL+G+R+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RVWRLFIDDNGGLNEKIVEGAGETLERVYHETVMKVTDHFEGLRFNTGISQLMVFINEAY  688
            RV RL+   +      I E  + +L++VY+ETV  VT++ + ++FNT+I+QLMVF+N A 
Sbjct  663  RVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  689  KADQLPKEYMEGFVKLLSPVAPHLAEELWNRL-GHEETIAYEAWPVYDEAKLVDDEIEIV  747
            K D+L  +Y  GFV+L++P APHL+EELW+ L +  E+I+Y +WP YDE+KLV++++EIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  748  VQLNGKVKAKLNVPADADKEQLEELAKNNEKVKEQLEGKTIRKVIAVPGKLVNIVAN  804
            VQ++GKVKAKL V+ D  +E+L+E+A  NEKV+ ++ GK I KVIAVP KLVNIV +
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

251) leuS in NC_006322


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  910 bits (3448),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 565/837 (68%), Positives = 669/837 (80%), Gaps = 42/837 (5%)

Query  3    FDHQTIEKKWQDYWLKNKTFATREDKSKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  62
            +DH +IE KWQ +W  N TF T  D SKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMKRMQGYNVLHPMGWDAFGLPAEQYALDTGNDPAVFTEQNIDNFRRQIRALGFSYDWDR  122
            R KR QG NVLHPMGWDAFGLPAEQYA+DTGNDPA FT +NI NF+RQI ALGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVNTTDPDYYKWTQWIFLKLYEKGLAYVDEVPVNWCPALGTVLANEEVI-DGKSERGGHP  181
            EVNTTDP+YYKWTQWIF KLYEKGLAY  EVPVNW   LGT +ANEEV+ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRPMKQWMLKITAYAdrlledleeldWPESIKEMQRNWIGRSEGAHVHFAVDGTNETF  241
            V R+PM+QWMLKITAYA+RLLEDLEE+DWPESIK+MQRNWIG+S GA+V F V +T+  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  TVFTTRPDTLFGATYAVLAPEHDLVQKITTPEQKDAVNAYIEEVQSKSDLERTDLAKTKT  301
            TVFTTRPDTLFGATYAVLAPEH LV+ ITT++Q +AV  Y  +   KSDL RTDLAK KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAVNPANGEKIPVWIADYVLATYGTGAVMAVPAHDERDHEFASAFGLPIKEVVK  361
            GV TG+YA+NP NG  +PVWIADYVLA+YGTGA+MAVPAHDERD EFA  F L I  V+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGDVEKEAYTGDGEHIHSDFLNGLDKAAAIEKMIQWLEENGKGEKKVTYRLRDWLFSRQR  421
            GG+VE  A+T DG HI+SDFL+GLDKA+AI KM++WLE +G G+ +VTYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPIIHWEDGTSTPVpeeelplilpKTSEIKPSGTGESPLANIKEWVEVTDPETGK  481
            YWGEPIPIIHWEDGTST+VPE ELPL+LP T +I+PSGTGESPLAN+ +W+EVT  E G 
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT-REDGV  482

Query  482  KGRRETNTMPQWAGSCWYFLRYIDPKNPNELASPEKLKEWLPVDMYIGGAEHAVLHLLYA  541
            KGRRETNTMPQWAGS WY+LRYIDP N + LA  E LK+WLPVD+Y+GGAEHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKFLYDIGVVPTKEPFKQLYNQGMILG------------------------------  571
            RFWHK LYD+GVVPTKEPF++L+NQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---ENNEKMSKSKGNVVNPDEIVETHGADTLRLYEMFMGPLDASIAWSTTGLDGARRFLD  628
               +   KMSKS  NVVNPD++VE  GADTLR+YEMFMGPLDASIAWS  GL+G+R+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RVWRLFIDDNGGLNEKIVEGAGETLERVYHETVMKVTDHFEGLRFNTGISQLMVFINEAY  688
            RV RL+   +      I E  + +L++VY+ETV  VT++ + ++FNT+I+QLMVF+N A 
Sbjct  663  RVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  689  KADQLPKEYMEGFVKLLSPVAPHLAEELWNRL-GHEETIAYEAWPVYDEAKLVDDEIEIV  747
            K D+L  +Y  GFV+L++P APHL+EELW+ L +  E+I+Y +WP YDE+KLV++++EIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  748  VQLNGKVKAKLNVPADADKEQLEELAKNNEKVKEQLEGKTIRKVIAVPGKLVNIVAN  804
            VQ++GKVKAKL V+ D  +E+L+E+A  NEKV+ ++ GK I KVIAVP KLVNIV +
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

252) leuS in NC_009725


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  909 bits (3443),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 562/837 (68%), Positives = 670/837 (81%), Gaps = 42/837 (5%)

Query  3    FQHEKIEKKWQNYWLDHKTFAVSEENDKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  62
            ++H  IE KWQ +W D+ TF  + +  KPKFYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMRRMQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTKQNIDNFRRQIQSLGFSYDWDR  122
            R +R QG NVLHPMGWDAFGLPAEQYA+DTGNDPAEFT +NI NF+RQI++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EINTTDPDYYKWTQWIFTKLYEKGLAYVDEVPVNWCPALGTVLANEEVI-DGKSERGGHP  181
            E+NTTDP+YYKWTQWIFTKLYEKGLAY  EVPVNW   LGT +ANEEV+ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRPMRQWMLKITAYAdrlledledldWPESIKDMQRNWIGRSEGANVHFAIdgtddtf  241
            V R+PMRQWMLKITAYA+RLLEDLE++DWPESIKDMQRNWIG+S GANV F + +TD  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  tvfttrpdtLFGAAYAVLAPEHELVEAITTPEQKEAVDAYVKEVQAKSDLERTDLAKTKT  301
            TVFTTRPDTLFGA+YAVLAPEH LV+AITT++Q EAV  Y ++   KSDL RTDLAK KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAVNPANGEKLPIWIADYVLASYGTGAVMAVPAHDERDFEFAKVFSLPVKEVVK  361
            GV TG+YA+NP NG  +P+WIADYVLASYGTGA+MAVPAHDERD EFAK F+L +  V+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGNTEEEAYTGDGEHVNSGFLNGLKKAEAIEKMIAWLEETKNGEKKVTYRLRDWLFSRQR  421
            GGN EE A+T DG H+NS+FL+GL KA AI KM+ WLE    G+ +VTYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPVIHWEDGTSTAVPAEELPLILPKTDEIKPSGTGESPLANIKEWVEVTDPETGK  481
            YWGEPIP+IHWEDGTSTAVP  ELPL+LP T +I+PSGTGESPLAN+ +W+EVT  E G 
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT-REDGV  482

Query  482  KGRRETNTMPQWAGSCWYFLRFIDPKNPDQLASPEKLDKWLPVDIYIGGAEHAVLHLLYA  541
            KGRRETNTMPQWAGS WY+LR+IDP N ++LA  E L +WLPVDIY+GGAEHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKFLYDIGVVPTKEPFQKLYNQGMILG------------------------------  571
            RFWHK LYD+GVVPTKEPFQKL+NQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---ENNEKMSKSRGNVVNPDEIVASHGADTLRLYEMFMGPLDASIAWSESGLDGARRFLD  628
               +   KMSKS  NVVNPD++V   GADTLR+YEMFMGPLDASIAWSE GL+G+R+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RVWRLFIEENGELTGKVTEGAGETLERVYHETVMKVTENFEALRFNTGISQLMVFINEAY  688
            RV RL+       T  +TE  + +L++VY+ETV  VTE+ + ++FNT+I+QLMVF+N A 
Sbjct  663  RVYRLIT------TKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  689  KANELPREYIEGFVKLLSPIAPHLAEELWEKLGHEG-SIAYEAWPAYDESKLVDDEVEIV  747
            K + L  +Y  GFV+L++P+APHL+EELW+ L   G SI+Y +WP+YDESKLV+++VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  748  VQLNGKVKAKLMVPADADKAALEQLAQADEKVKEQLEGKTIRKIIAVPGKLVNIVAN  804
            VQ++GKVKAKL+V+ D  +  L+++A A+EKV+ ++ GK I K+IAVP KLVNIV +
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

253) leuS in NC_020272


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  909 bits (3442),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 563/837 (68%), Positives = 670/837 (81%), Gaps = 42/837 (5%)

Query  3    FQHEKIEKKWQNYWLDHKTFAVSEENDKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  62
            ++H  IE KWQ +W D+ TF  + +  KPKFYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMRRMQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTKQNIDNFRRQIQSLGFSYDWDR  122
            R +R QG NVLHPMGWDAFGLPAEQYA+DTGNDPAEFT +NI NF+RQI++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EINTTDPDYYKWTQWIFTKLYEKGLAYVDEVPVNWCPALGTVLANEEVI-DGKSERGGHP  181
            E+NTTDP+YYKWTQWIFTKLYEKGLAY  EVPVNW   LGT +ANEEV+ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRPMRQWMLKITAYAdrlledleeldWPESIKDMQRNWIGRSEGANVHFAIdgtddtf  241
            V R+PMRQWMLKITAYA+RLLEDLEE+DWPESIKDMQRNWIG+S GANV F + +TD  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  tvfttrpdtLFGAAYAVLAPEHELVEAITTPEQKEAVDAYVKEVQAKSDLERTDLAKTKT  301
            TVFTTRPDTLFGA+YAVLAPEH LV+AITT++Q EAV  Y ++   KSDL RTDLAK KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAVNPANGEKLPIWIADYVLASYGTGAVMAVPAHDERDFEFAKVFSLPVKEVVK  361
            GV TG+YA+NP NG  +P+WIADYVLASYGTGA+MAVPAHDERD EFAK F+L +  V+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGNTEEEAYTGDGEHVNSGFLNGLNKAEAIEKMIAWLEETKNGEKKVTYRLRDWLFSRQR  421
            GGN EE A+T DG H+NS+FL+GL+KA AI KM+ WLE    G+ +VTYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPVIHWEDGTSTAVPAEELPLILPKTDEIKPSGTGESPLANIKEWVEVTDPETGR  481
            YWGEPIP+IHWEDGTSTAVP  ELPL+LP T +I+PSGTGESPLAN+ +W+EVT  E G 
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT-REDGV  482

Query  482  KGRRETNTMPQWAGSCWYFLRFIDPKNPDQLASPEKLDKWLPVDIYIGGAEHAVLHLLYA  541
            KGRRETNTMPQWAGS WY+LR+IDP N ++LA  E L +WLPVDIY+GGAEHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKFLYDIGVVPTKEPFQKLYNQGMILG------------------------------  571
            RFWHK LYD+GVVPTKEPFQKL+NQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---ENNEKMSKSRGNVVNPDEIVASHGADTLRLYEMFMGPLDASIAWSESGLDGARRFLD  628
               +   KMSKS  NVVNPD++V   GADTLR+YEMFMGPLDASIAWSE GL+G+R+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RVWRLFIEENGELTGKVTEGAGETLERVYHETVMKVTENFEALRFNTGISQLMVFINEAY  688
            RV RL+       T  +TE  + +L++VY+ETV  VTE+ + ++FNT+I+QLMVF+N A 
Sbjct  663  RVYRLIT------TKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  689  KANELPREYIEGFVKLLSPVAPHLAEELWEKLGHEG-SIAYEAWPAYDESKLVDDEVEIV  747
            K + L  +Y  GFV+L++P APHL+EELW+ L   G SI+Y +WP+YDESKLV+++VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  748  VQLNGKVKAKLMVPADADKAALEQLAQADEKVKEQLEGKTIRKIIAVPGKLVNIVAN  804
            VQ++GKVKAKL+V+ D  +  L+++A A+EKV+ ++ GK I K+IAVP KLVNIV +
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

254) leuS in NC_016784


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  909 bits (3442),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 563/837 (68%), Positives = 670/837 (81%), Gaps = 42/837 (5%)

Query  3    FQHEKIEKKWQNYWLDHKTFAVSEENDKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  62
            ++H  IE KWQ +W D+ TF  + +  KPKFYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMRRMQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTKQNIDNFRRQIQSLGFSYDWDR  122
            R +R QG NVLHPMGWDAFGLPAEQYA+DTGNDPAEFT +NI NF+RQI++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EINTTDPDYYKWTQWIFTKLYEKGLAYVDEVPVNWCPALGTVLANEEVI-DGKSERGGHP  181
            E+NTTDP+YYKWTQWIFTKLYEKGLAY  EVPVNW   LGT +ANEEV+ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRPMRQWMLKITAYAdrlledleeldWPESIKDMQRNWIGRSEGANVHFAIdgtddtf  241
            V R+PMRQWMLKITAYA+RLLEDLEE+DWPESIKDMQRNWIG+S GANV F + +TD  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  tvfttrpdtLFGAAYAVLAPEHELVEAITTPEQKEAVDAYVKEVQAKSDLERTDLAKTKT  301
            TVFTTRPDTLFGA+YAVLAPEH LV+AITT++Q EAV  Y ++   KSDL RTDLAK KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAVNPANGEKLPIWIADYVLASYGTGAVMAVPAHDERDFEFAKVFSLPVKEVVK  361
            GV TG+YA+NP NG  +P+WIADYVLASYGTGA+MAVPAHDERD EFAK F+L +  V+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGNTEEEAYTGDGEHVNSGFLNGLNKAEAIEKMIAWLEETKNGEKKVTYRLRDWLFSRQR  421
            GGN EE A+T DG H+NS+FL+GL+KA AI KM+ WLE    G+ +VTYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPVIHWEDGTSTAVPAEELPLILPKTDEIKPSGTGESPLANIKEWVEVTDPETGR  481
            YWGEPIP+IHWEDGTSTAVP  ELPL+LP T +I+PSGTGESPLAN+ +W+EVT  E G 
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT-REDGV  482

Query  482  KGRRETNTMPQWAGSCWYFLRFIDPKNPDQLASPEKLDKWLPVDIYIGGAEHAVLHLLYA  541
            KGRRETNTMPQWAGS WY+LR+IDP N ++LA  E L +WLPVDIY+GGAEHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKFLYDIGVVPTKEPFQKLYNQGMILG------------------------------  571
            RFWHK LYD+GVVPTKEPFQKL+NQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---ENNEKMSKSRGNVVNPDEIVASHGADTLRLYEMFMGPLDASIAWSESGLDGARRFLD  628
               +   KMSKS  NVVNPD++V   GADTLR+YEMFMGPLDASIAWSE GL+G+R+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RVWRLFIEENGELTGKVTEGAGETLERVYHETVMKVTENFEALRFNTGISQLMVFINEAY  688
            RV RL+       T  +TE  + +L++VY+ETV  VTE+ + ++FNT+I+QLMVF+N A 
Sbjct  663  RVYRLIT------TKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  689  KANELPREYIEGFVKLLSPVAPHLAEELWEKLGHEG-SIAYEAWPAYDESKLVDDEVEIV  747
            K + L  +Y  GFV+L++P APHL+EELW+ L   G SI+Y +WP+YDESKLV+++VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  748  VQLNGKVKAKLMVPADADKAALEQLAQADEKVKEQLEGKTIRKIIAVPGKLVNIVAN  804
            VQ++GKVKAKL+V+ D  +  L+++A A+EKV+ ++ GK I K+IAVP KLVNIV +
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

255) leuS in NC_020410


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  909 bits (3442),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 562/837 (68%), Positives = 669/837 (80%), Gaps = 42/837 (5%)

Query  3    FQHEKIEKKWQNYWLDHKTFAVSEENDKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  62
            ++H  IE KWQ +W D+ TF  + +  KPKFYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMRRMQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTKQNIDNFRRQIQSLGFSYDWDR  122
            R +R QG NVLHPMGWDAFGLPAEQYA+DTGNDPAEFT +NI NF+RQI++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EINTTDPDYYKWTQWIFTKLYEKGLAYVDEVPVNWCPALGTVLANEEVI-DGKSERGGHP  181
            E+NTTDP+YYKWTQWIFTKLYEKGLAY  EVPVNW   LGT +ANEEV+ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRPMRQWMLKITAYAdrlledleeldWPESIKDMQRNWIGRSEGANVHFAIdgtddtf  241
            V R+PMRQWMLKITAYA+RLLEDLEE+DWPESIKDMQRNWIG+S GANV F + +TD  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  tvfttrpdtLFGAAYAVLAPEHELVEVITTPEQKEAVDAYVKEVQAKSDLERTDLAKTKT  301
            TVFTTRPDTLFGA+YAVLAPEH LV+ ITT++Q EAV  Y ++   KSDL RTDLAK KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAVNPANGEKLPIWIADYVLASYGTGAVMAVPAHDERDFEFAKVFSLPVKEVVK  361
            GV TG+YA+NP NG  +P+WIADYVLASYGTGA+MAVPAHDERD EFAK F+L +  V+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGNTEEEAYTGDGEHVNSGFLNGLNKAEAIEKMIAWLEETKNGEKKVTYRLRDWLFSRQR  421
            GGN EE A+T DG H+NS+FL+GL+KA AI KM+ WLE    G+ +VTYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPVIHWEDGTSTAVPAEELPLILPKTDEIKPSGTGESPLANIKEWVEVTDPETGR  481
            YWGEPIP+IHWEDGTSTAVP  ELPL+LP T +I+PSGTGESPLAN+ +W+EVT  E G 
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT-REDGV  482

Query  482  KGRRETNTMPQWAGSCWYFLRFIDPKNPDQLASPEKLDKWLPVDIYIGGAEHAVLHLLYA  541
            KGRRETNTMPQWAGS WY+LR+IDP N ++LA  E L +WLPVDIY+GGAEHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKFLYDIGVVPTKEPFQKLYNQGMILG------------------------------  571
            RFWHK LYD+GVVPTKEPFQKL+NQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---ENNEKMSKSRGNVVNPDEIVASHGADTLRLYEMFMGPLDASIAWSESGLDGARRFLD  628
               +   KMSKS  NVVNPD++V   GADTLR+YEMFMGPLDASIAWSE GL+G+R+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RVWRLFIEENGELTGKVTEGAGETLERVYHETVMKVTENFEALRFNTGISQLMVFINEAY  688
            RV RL+       T  +TE  + +L++VY+ETV  VTE+ + ++FNT+I+QLMVF+N A 
Sbjct  663  RVYRLIT------TKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  689  KANELPREYIEGFVKLLSPVAPHLAEELWEKLGHEG-SIAYEAWPAYDESKLVDDEVEIV  747
            K + L  +Y  GFV+L++P APHL+EELW+ L   G SI+Y +WP+YDESKLV+++VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  748  VQLNGKVKAKLMVPADADKAALEQLAQADEKVKEQLEGKTIRKIIAVPGKLVNIVAN  804
            VQ++GKVKAKL+V+ D  +  L+++A A+EKV+ ++ GK I K+IAVP KLVNIV +
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

256) leuS in NC_017061


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  909 bits (3445),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 563/837 (68%), Positives = 671/837 (81%), Gaps = 42/837 (5%)

Query  3    FQHEKIEKKWQNYWLDHKTFAVSEENDKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  62
            ++H  IE KWQ +W D+ TF  + +  KPKFYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMRRMQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTKQNIDNFRRQIQSLGFSYDWDR  122
            R +R QG NVLHPMGWDAFGLPAEQYA+DTGNDPAEFT +NI NF+RQI++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EINTTDPDYYKWTQWIFTKLYEKGLAYVDEVPVNWCPALGTVLANEEVI-DGKSERGGHP  181
            E+NTTDP+YYKWTQWIFTKLYEKGLAY  EVPVNW   LGT +ANEEV+ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRPMRQWMLKITAYAdrlledleeldWPESIKDMQRNWIGRSEGANVHFAIdgtddtf  241
            V R+PMRQWMLKITAYA+RLLEDLEE+DWPESIKDMQRNWIG+S GANV F + +TD  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  tvfttrpdtLFGAAYAVLAPEHELVEAITTPEQKEAVDAYVKEVQAKSDLERTDLAKTKT  301
            TVFTTRPDTLFGA+YAVLAPEH LV+AITT++Q EAV  Y ++   KSDL RTDLAK KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAVNPANGEKLPIWIADYVLASYGTGAVMAVPAHDERDFEFAKVFSLPVKEVVK  361
            GV TG+YA+NP NG  +P+WIADYVLASYGTGA+MAVPAHDERD EFAK F+L +  V+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGNTEEEAYTGDGEHVNSGFLNGLNKAEAIEKMIAWLEETKNGEKKVTYRLRDWLFSRQR  421
            GGN EE A+T DG H+NS+FL+GL+KA AI KM+ WLE    G+ +VTYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPVIHWEDGTSTAVPAEELPLILPKTDEIKPSGTGESPLANIKEWVEVTDPETGK  481
            YWGEPIP+IHWEDGTSTAVP  ELPL+LP T +I+PSGTGESPLAN+ +W+EVT  E G 
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT-REDGV  482

Query  482  KGRRETNTMPQWAGSCWYFLRFIDPKNPDQLASPEKLDKWLPVDIYIGGAEHAVLHLLYA  541
            KGRRETNTMPQWAGS WY+LR+IDP N ++LA  E L +WLPVDIY+GGAEHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKFLYDIGVVPTKEPFQKLYNQGMILG------------------------------  571
            RFWHK LYD+GVVPTKEPFQKL+NQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---ENNEKMSKSRGNVVNPDEIVASHGADTLRLYEMFMGPLDASIAWSESGLDGARRFLD  628
               +   KMSKS  NVVNPD++V   GADTLR+YEMFMGPLDASIAWSE GL+G+R+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RVWRLFIEENGELTGKVTEGAGETLERVYHETVMKVTENFEALRFNTGISQLMVFINEAY  688
            RV RL+       T  +TE  + +L++VY+ETV  VTE+ + ++FNT+I+QLMVF+N A 
Sbjct  663  RVYRLIT------TKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  689  KANELPREYIEGFVKLLSPIAPHLAEELWEKLGHEG-SIAYEAWPAYDESKLVDDEVEIV  747
            K + L  +Y  GFV+L++P+APHL+EELW+ L   G SI+Y +WP+YDESKLV+++VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  748  VQLNGKVKAKLMVPADADKAVLEQLAQADEKVKEQLEGKTIRKIIAVPGKLVNIVAN  804
            VQ++GKVKAKL+V+ D  +  L+++A A+EKV+ ++ GK I K+IAVP KLVNIV +
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

257) leuS in NC_017912


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  909 bits (3445),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 563/837 (68%), Positives = 671/837 (81%), Gaps = 42/837 (5%)

Query  3    FQHEKIEKKWQNYWLDHKTFAVSEENDKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  62
            ++H  IE KWQ +W D+ TF  + +  KPKFYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMRRMQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTKQNIDNFRRQIQSLGFSYDWDR  122
            R +R QG NVLHPMGWDAFGLPAEQYA+DTGNDPAEFT +NI NF+RQI++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EINTTDPDYYKWTQWIFTKLYEKGLAYVDEVPVNWCPALGTVLANEEVI-DGKSERGGHP  181
            E+NTTDP+YYKWTQWIFTKLYEKGLAY  EVPVNW   LGT +ANEEV+ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRPMRQWMLKITAYAdrlledleeldWPESIKDMQRNWIGRSEGANVHFAIdgtddtf  241
            V R+PMRQWMLKITAYA+RLLEDLEE+DWPESIKDMQRNWIG+S GANV F + +TD  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  tvfttrpdtLFGAAYAVLAPEHELVEAITTPEQKEAVDAYVKEVQAKSDLERTDLAKTKT  301
            TVFTTRPDTLFGA+YAVLAPEH LV+AITT++Q EAV  Y ++   KSDL RTDLAK KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAVNPANGEKLPIWIADYVLASYGTGAVMAVPAHDERDFEFAKVFSLPVKEVVK  361
            GV TG+YA+NP NG  +P+WIADYVLASYGTGA+MAVPAHDERD EFAK F+L +  V+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGNTEEEAYTGDGEHVNSGFLNGLNKAEAIEKMIAWLEETKNGEKKVTYRLRDWLFSRQR  421
            GGN EE A+T DG H+NS+FL+GL+KA AI KM+ WLE    G+ +VTYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPVIHWEDGTSTAVPAEELPLILPKTDEIKPSGTGESPLANIKEWVEVTDPETGK  481
            YWGEPIP+IHWEDGTSTAVP  ELPL+LP T +I+PSGTGESPLAN+ +W+EVT  E G 
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT-REDGV  482

Query  482  KGRRETNTMPQWAGSCWYFLRFIDPKNPDQLASPEKLDKWLPVDIYIGGAEHAVLHLLYA  541
            KGRRETNTMPQWAGS WY+LR+IDP N ++LA  E L +WLPVDIY+GGAEHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKFLYDIGVVPTKEPFQKLYNQGMILG------------------------------  571
            RFWHK LYD+GVVPTKEPFQKL+NQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---ENNEKMSKSRGNVVNPDEIVASHGADTLRLYEMFMGPLDASIAWSESGLDGARRFLD  628
               +   KMSKS  NVVNPD++V   GADTLR+YEMFMGPLDASIAWSE GL+G+R+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RVWRLFIEENGELTGKVTEGAGETLERVYHETVMKVTENFEALRFNTGISQLMVFINEAY  688
            RV RL+       T  +TE  + +L++VY+ETV  VTE+ + ++FNT+I+QLMVF+N A 
Sbjct  663  RVYRLIT------TKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  689  KANELPREYIEGFVKLLSPIAPHLAEELWEKLGHEG-SIAYEAWPAYDESKLVDDEVEIV  747
            K + L  +Y  GFV+L++P+APHL+EELW+ L   G SI+Y +WP+YDESKLV+++VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  748  VQLNGKVKAKLMVPADADKAVLEQLAQADEKVKEQLEGKTIRKIIAVPGKLVNIVAN  804
            VQ++GKVKAKL+V+ D  +  L+++A A+EKV+ ++ GK I K+IAVP KLVNIV +
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

258) leuS in NC_022075


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  908 bits (3440),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 561/837 (68%), Positives = 670/837 (81%), Gaps = 42/837 (5%)

Query  3    FQHEKIEKKWQNYWLDHKTFAVSEENDKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  62
            ++H  IE KWQ +W D+ TF  + +  KPKFYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMRRMQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTKQNIDNFRRQIQSLGFSYDWDR  122
            R +R QG NVLHPMGWDAFGLPAEQYA+DTGNDPAEFT +NI NF+RQI++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EINTTDPDYYKWTQWIFTKLYEKGLAYVDEVPVNWCPALGTVLANEEVI-DGKSERGGHP  181
            E+NTTDP+YYKWTQWIFTKLYEKGLAY  EVPVNW   LGT +ANEEV+ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRPMRQWMLKITAYAdrlledledldWPESIKDMQRNWIGRSEGANVHFAIdgtddtf  241
            V R+PMRQWMLKITAYA+RLLEDLE++DWPESIKDMQRNWIG+S GANV F + +TD  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  tvfttrpdtLFGAAYAVLAPEHELVEAITTPEQKEAVDAYVKEVQAKSDLERTDLAKTKT  301
            TVFTTRPDTLFGA+YAVLAPEH LV+AITT++Q EAV  Y ++   KSDL RTDLAK KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAVNPANGEKLPIWIADYVLASYGTGAVMAVPAHDERDFEFAKVFSLPVKEVVK  361
            GV TG+YA+NP NG  +P+WIADYVLASYGTGA+MAVPAHDERD EFAK F+L +  V+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGNTEEEAYTGDGEHVNSGFLNGLNKAEAIEKMIAWLEETKNGEKKVTYRLRDWLFSRQR  421
            GGN EE A+T DG H+NS+FL+GL+KA AI KM+ WLE    G+ +VTYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPVIHWEDGTSTAVPAEELPLILPKTDEIKPSGTGESPLANIKEWVEVTDPVTGK  481
            YWGEPIP+IHWEDGTSTAVP  ELPL+LP T +I+PSGTGESPLAN+ +W+EVT    G 
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRE-DGV  482

Query  482  KGRRETNTMPQWAGSCWYFLRFIDPKNPDQLASPEKLDKWLPVDIYIGGAEHAVLHLLYA  541
            KGRRETNTMPQWAGS WY+LR+IDP N ++LA  E L +WLPVDIY+GGAEHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKFLYDIGVVPTKEPFQKLYNQGMILG------------------------------  571
            RFWHK LYD+GVVPTKEPFQKL+NQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---ENNEKMSKSRGNVVNPDEIVASHGADTLRLYEMFMGPLDASIAWSESGLDGARRFLD  628
               +   KMSKS  NVVNPD++V   GADTLR+YEMFMGPLDASIAWSE GL+G+R+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RVWRLFIEENGELTGKVTEGAGETLERVYHETVMKVTENFEALRFNTGISQLMVFINEAY  688
            RV RL+       T  +TE  + +L++VY+ETV  VTE+ + ++FNT+I+QLMVF+N A 
Sbjct  663  RVYRLIT------TKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  689  KANELPREYIEGFVKLLSPIAPHLAEELWEKLGHEG-SIAYEAWPAYDESKLVDDEVEIV  747
            K + L  +Y  GFV+L++P+APHL+EELW+ L   G SI+Y +WP+YDESKLV+++VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  748  VQLNGKVKAKLMVPADADKAALEQLAQADEKVKEQLEGKTIRKIIAVPGKLVNIVAN  804
            VQ++GKVKAKL+V+ D  +  L+++A A+EKV+ ++ GK I K+IAVP KLVNIV +
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

259) leuS in NC_022081


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  908 bits (3440),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 561/837 (68%), Positives = 670/837 (81%), Gaps = 42/837 (5%)

Query  3    FQHEKIEKKWQNYWLDHKTFAVSEENDKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  62
            ++H  IE KWQ +W D+ TF  + +  KPKFYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMRRMQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTKQNIDNFRRQIQSLGFSYDWDR  122
            R +R QG NVLHPMGWDAFGLPAEQYA+DTGNDPAEFT +NI NF+RQI++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EINTTDPDYYKWTQWIFTKLYEKGLAYVDEVPVNWCPALGTVLANEEVI-DGKSERGGHP  181
            E+NTTDP+YYKWTQWIFTKLYEKGLAY  EVPVNW   LGT +ANEEV+ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRPMRQWMLKITAYAdrlledledldWPESIKDMQRNWIGRSEGANVHFAIdgtddtf  241
            V R+PMRQWMLKITAYA+RLLEDLE++DWPESIKDMQRNWIG+S GANV F + +TD  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  tvfttrpdtLFGAAYAVLAPEHELVEAITTPEQKEAVDAYVKEVQAKSDLERTDLAKTKT  301
            TVFTTRPDTLFGA+YAVLAPEH LV+AITT++Q EAV  Y ++   KSDL RTDLAK KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAVNPANGEKLPIWIADYVLASYGTGAVMAVPAHDERDFEFAKVFSLPVKEVVK  361
            GV TG+YA+NP NG  +P+WIADYVLASYGTGA+MAVPAHDERD EFAK F+L +  V+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGNTEEEAYTGDGEHVNSGFLNGLNKAEAIEKMIAWLEETKNGEKKVTYRLRDWLFSRQR  421
            GGN EE A+T DG H+NS+FL+GL+KA AI KM+ WLE    G+ +VTYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPVIHWEDGTSTAVPAEELPLILPKTDEIKPSGTGESPLANIKEWVEVTDPVTGK  481
            YWGEPIP+IHWEDGTSTAVP  ELPL+LP T +I+PSGTGESPLAN+ +W+EVT    G 
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRE-DGV  482

Query  482  KGRRETNTMPQWAGSCWYFLRFIDPKNPDQLASPEKLDKWLPVDIYIGGAEHAVLHLLYA  541
            KGRRETNTMPQWAGS WY+LR+IDP N ++LA  E L +WLPVDIY+GGAEHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKFLYDIGVVPTKEPFQKLYNQGMILG------------------------------  571
            RFWHK LYD+GVVPTKEPFQKL+NQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---ENNEKMSKSRGNVVNPDEIVASHGADTLRLYEMFMGPLDASIAWSESGLDGARRFLD  628
               +   KMSKS  NVVNPD++V   GADTLR+YEMFMGPLDASIAWSE GL+G+R+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RVWRLFIEENGELTGKVTEGAGETLERVYHETVMKVTENFEALRFNTGISQLMVFINEAY  688
            RV RL+       T  +TE  + +L++VY+ETV  VTE+ + ++FNT+I+QLMVF+N A 
Sbjct  663  RVYRLIT------TKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  689  KANELPREYIEGFVKLLSPIAPHLAEELWEKLGHEG-SIAYEAWPAYDESKLVDDEVEIV  747
            K + L  +Y  GFV+L++P+APHL+EELW+ L   G SI+Y +WP+YDESKLV+++VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  748  VQLNGKVKAKLMVPADADKAALEQLAQADEKVKEQLEGKTIRKIIAVPGKLVNIVAN  804
            VQ++GKVKAKL+V+ D  +  L+++A A+EKV+ ++ GK I K+IAVP KLVNIV +
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

260) leuS in NC_014551


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  908 bits (3438),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 558/837 (67%), Positives = 671/837 (81%), Gaps = 42/837 (5%)

Query  3    FQHEKIEKKWQNYWLEHKTFAASEENDKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  62
            ++H  IE KWQ +W ++ TF ++ +  KPKFYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMRRMQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTKHNIDNFRRQIQSLGFSYDWDR  122
            R +R QG NVLHPMGWDAFGLPAEQYA+DTGNDPAEFT +NI NF+RQI++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EINTTDPDYYKWTQWIFTKLYEKGLAYVDEVPVNWCPALGTVLANEEVI-DGKSERGGHP  181
            E+NTTDP+YYKWTQWIFTKLYEKGLAY  EVPVNW   LGT +ANEEV+ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRPMKQWMLKITAYAdrlledledldWPESIKDMQRNWIGRSEGANVHFAIdgtddtf  241
            V R+PM+QWMLKITAYA+RLLEDLE++DWPESIKDMQRNWIG+S GANV F + +TD  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  tvfttrpdtLFGAAYAVLAPEHELVEAITTAEQKEAVDAYIKEVQAKSDLERTDLAKTKT  301
            TVFTTRPDTLFGA+YAVLAPEH LV+AITT++Q EAV  Y ++   KSDL RTDLAK KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAVNPANGEKLPIWIADYVLATYGTGAVMAVPAHDERDFEFAKVFSLPVKEVVK  361
            GV TG+YA+NP NG  +P+WIADYVLA+YGTGA+MAVPAHDERD EFAK F+L +  V+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGNTDEEAYTGDGEHVNSGFLNGLNKAEAIEKMIAWLEETKNGEKKVTYRLRDWLFSRQR  421
            GGN +E A+T DG H+NS+FL+GL+KA AI KM+ WLE    G+ +VTYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPVIHWEDGTSTAVPAEELPLILPKTDEIKPSGTGESPLANIKEWVEVTDPETGR  481
            YWGEPIP+IHWEDGTSTAVP  ELPL+LP T +I+PSGTGESPLAN+ +W+EVT  E G 
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT-REDGV  482

Query  482  KGRRETNTMPQWAGSCWYFLRFIDPKNPDQLASPEKLDKWLPVDIYIGGAEHAVLHLLYA  541
            KGRRETNTMPQWAGS WY+LR+IDP N ++LA  E L +WLPVDIY+GGAEHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKFLYDIGVVPTKEPFQKLYNQGMILG------------------------------  571
            RFWHK LYD+GVVPTKEPFQKL+NQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---ENNEKMSKSRGNVVNPDEIVASHGADTLRLYEMFMGPLDASIAWSESGLDGARRFLD  628
               +   KMSKS  NVVNPD++V   GADTLR+YEMFMGPLDASIAWSE GL+G+R+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RVWRLFIEENGELTGKVTEGAGETLERVYHETVMKVTENYEALRFNTGISQLMVFINEAY  688
            RV RL+       T  +TE  + +L++VY+ETV  VTE+ + ++FNT+I+QLMVF+N A 
Sbjct  663  RVYRLIT------TKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  689  KANELPREYMEGFVKLLSPVAPHLAEELWEKLGHEG-SIAYEAWPAYDESKLVDDEVEIV  747
            K + L  +Y  GFV+L++P APHL+EELW+ L   G SI+Y +WP+YDESKLV+++VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  748  VQLNGKVKAKLMVPADADKAALEQLAQADEKVKEQLEGKTIRKIIAVPGKLVNIVAN  804
            VQ++GKVKAKL+V+ D  +  L+++A A+EKV+ ++ GK I K+IAVP KLVNIV +
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

261) leuS in NC_017190


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  908 bits (3438),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 558/837 (67%), Positives = 671/837 (81%), Gaps = 42/837 (5%)

Query  3    FQHEKIEKKWQNYWLEHKTFAASEENDKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  62
            ++H  IE KWQ +W ++ TF ++ +  KPKFYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMRRMQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTKHNIDNFRRQIQSLGFSYDWDR  122
            R +R QG NVLHPMGWDAFGLPAEQYA+DTGNDPAEFT +NI NF+RQI++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EINTTDPDYYKWTQWIFTKLYEKGLAYVDEVPVNWCPALGTVLANEEVI-DGKSERGGHP  181
            E+NTTDP+YYKWTQWIFTKLYEKGLAY  EVPVNW   LGT +ANEEV+ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRPMKQWMLKITAYAdrlledledldWPESIKDMQRNWIGRSEGANVHFAIdgtddtf  241
            V R+PM+QWMLKITAYA+RLLEDLE++DWPESIKDMQRNWIG+S GANV F + +TD  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  tvfttrpdtLFGAAYAVLAPEHELVEAITTAEQKEAVDAYIKEVQAKSDLERTDLAKTKT  301
            TVFTTRPDTLFGA+YAVLAPEH LV+AITT++Q EAV  Y ++   KSDL RTDLAK KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAVNPANGEKLPIWIADYVLATYGTGAVMAVPAHDERDFEFAKVFSLPVKEVVK  361
            GV TG+YA+NP NG  +P+WIADYVLA+YGTGA+MAVPAHDERD EFAK F+L +  V+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGNTDEEAYTGDGEHVNSGFLNGLNKAEAIEKMIAWLEETKNGEKKVTYRLRDWLFSRQR  421
            GGN +E A+T DG H+NS+FL+GL+KA AI KM+ WLE    G+ +VTYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPVIHWEDGTSTAVPAEELPLILPKTDEIKPSGTGESPLANIKEWVEVTDPETGR  481
            YWGEPIP+IHWEDGTSTAVP  ELPL+LP T +I+PSGTGESPLAN+ +W+EVT  E G 
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT-REDGV  482

Query  482  KGRRETNTMPQWAGSCWYFLRFIDPKNPDQLASPEKLDKWLPVDIYIGGAEHAVLHLLYA  541
            KGRRETNTMPQWAGS WY+LR+IDP N ++LA  E L +WLPVDIY+GGAEHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKFLYDIGVVPTKEPFQKLYNQGMILG------------------------------  571
            RFWHK LYD+GVVPTKEPFQKL+NQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---ENNEKMSKSRGNVVNPDEIVASHGADTLRLYEMFMGPLDASIAWSESGLDGARRFLD  628
               +   KMSKS  NVVNPD++V   GADTLR+YEMFMGPLDASIAWSE GL+G+R+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RVWRLFIEENGELTGKVTEGAGETLERVYHETVMKVTENYEALRFNTGISQLMVFINEAY  688
            RV RL+       T  +TE  + +L++VY+ETV  VTE+ + ++FNT+I+QLMVF+N A 
Sbjct  663  RVYRLIT------TKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  689  KANELPREYMEGFVKLLSPVAPHLAEELWEKLGHEG-SIAYEAWPAYDESKLVDDEVEIV  747
            K + L  +Y  GFV+L++P APHL+EELW+ L   G SI+Y +WP+YDESKLV+++VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  748  VQLNGKVKAKLMVPADADKAALEQLAQADEKVKEQLEGKTIRKIIAVPGKLVNIVAN  804
            VQ++GKVKAKL+V+ D  +  L+++A A+EKV+ ++ GK I K+IAVP KLVNIV +
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

262) leuS in NC_017188


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  908 bits (3438),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 558/837 (67%), Positives = 671/837 (81%), Gaps = 42/837 (5%)

Query  3    FQHEKIEKKWQNYWLEHKTFAASEENDKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  62
            ++H  IE KWQ +W ++ TF ++ +  KPKFYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMRRMQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTKHNIDNFRRQIQSLGFSYDWDR  122
            R +R QG NVLHPMGWDAFGLPAEQYA+DTGNDPAEFT +NI NF+RQI++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EINTTDPDYYKWTQWIFTKLYEKGLAYVDEVPVNWCPALGTVLANEEVI-DGKSERGGHP  181
            E+NTTDP+YYKWTQWIFTKLYEKGLAY  EVPVNW   LGT +ANEEV+ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRPMKQWMLKITAYAdrlledledldWPESIKDMQRNWIGRSEGANVHFAIdgtddtf  241
            V R+PM+QWMLKITAYA+RLLEDLE++DWPESIKDMQRNWIG+S GANV F + +TD  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  tvfttrpdtLFGAAYAVLAPEHELVEAITTAEQKEAVDAYIKEVQAKSDLERTDLAKTKT  301
            TVFTTRPDTLFGA+YAVLAPEH LV+AITT++Q EAV  Y ++   KSDL RTDLAK KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAVNPANGEKLPIWIADYVLATYGTGAVMAVPAHDERDFEFAKVFSLPVKEVVK  361
            GV TG+YA+NP NG  +P+WIADYVLA+YGTGA+MAVPAHDERD EFAK F+L +  V+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGNTDEEAYTGDGEHVNSGFLNGLNKAEAIEKMIAWLEETKNGEKKVTYRLRDWLFSRQR  421
            GGN +E A+T DG H+NS+FL+GL+KA AI KM+ WLE    G+ +VTYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPVIHWEDGTSTAVPAEELPLILPKTDEIKPSGTGESPLANIKEWVEVTDPETGR  481
            YWGEPIP+IHWEDGTSTAVP  ELPL+LP T +I+PSGTGESPLAN+ +W+EVT  E G 
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT-REDGV  482

Query  482  KGRRETNTMPQWAGSCWYFLRFIDPKNPDQLASPEKLDKWLPVDIYIGGAEHAVLHLLYA  541
            KGRRETNTMPQWAGS WY+LR+IDP N ++LA  E L +WLPVDIY+GGAEHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKFLYDIGVVPTKEPFQKLYNQGMILG------------------------------  571
            RFWHK LYD+GVVPTKEPFQKL+NQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---ENNEKMSKSRGNVVNPDEIVASHGADTLRLYEMFMGPLDASIAWSESGLDGARRFLD  628
               +   KMSKS  NVVNPD++V   GADTLR+YEMFMGPLDASIAWSE GL+G+R+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RVWRLFIEENGELTGKVTEGAGETLERVYHETVMKVTENYEALRFNTGISQLMVFINEAY  688
            RV RL+       T  +TE  + +L++VY+ETV  VTE+ + ++FNT+I+QLMVF+N A 
Sbjct  663  RVYRLIT------TKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  689  KANELPREYMEGFVKLLSPVAPHLAEELWEKLGHEG-SIAYEAWPAYDESKLVDDEVEIV  747
            K + L  +Y  GFV+L++P APHL+EELW+ L   G SI+Y +WP+YDESKLV+++VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  748  VQLNGKVKAKLMVPADADKAALEQLAQADEKVKEQLEGKTIRKIIAVPGKLVNIVAN  804
            VQ++GKVKAKL+V+ D  +  L+++A A+EKV+ ++ GK I K+IAVP KLVNIV +
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

263) leuS in NC_017191


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  908 bits (3438),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 558/837 (67%), Positives = 671/837 (81%), Gaps = 42/837 (5%)

Query  3    FQHEKIEKKWQNYWLEHKTFAASEENDKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  62
            ++H  IE KWQ +W ++ TF ++ +  KPKFYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMRRMQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTKHNIDNFRRQIQSLGFSYDWDR  122
            R +R QG NVLHPMGWDAFGLPAEQYA+DTGNDPAEFT +NI NF+RQI++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EINTTDPDYYKWTQWIFTKLYEKGLAYVDEVPVNWCPALGTVLANEEVI-DGKSERGGHP  181
            E+NTTDP+YYKWTQWIFTKLYEKGLAY  EVPVNW   LGT +ANEEV+ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRPMKQWMLKITAYAdrlledledldWPESIKDMQRNWIGRSEGANVHFAIdgtddtf  241
            V R+PM+QWMLKITAYA+RLLEDLE++DWPESIKDMQRNWIG+S GANV F + +TD  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  tvfttrpdtLFGAAYAVLAPEHELVEAITTAEQKEAVDAYIKEVQAKSDLERTDLAKTKT  301
            TVFTTRPDTLFGA+YAVLAPEH LV+AITT++Q EAV  Y ++   KSDL RTDLAK KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAVNPANGEKLPIWIADYVLATYGTGAVMAVPAHDERDFEFAKVFSLPVKEVVK  361
            GV TG+YA+NP NG  +P+WIADYVLA+YGTGA+MAVPAHDERD EFAK F+L +  V+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGNTDEEAYTGDGEHVNSGFLNGLNKAEAIEKMIAWLEETKNGEKKVTYRLRDWLFSRQR  421
            GGN +E A+T DG H+NS+FL+GL+KA AI KM+ WLE    G+ +VTYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPVIHWEDGTSTAVPAEELPLILPKTDEIKPSGTGESPLANIKEWVEVTDPETGR  481
            YWGEPIP+IHWEDGTSTAVP  ELPL+LP T +I+PSGTGESPLAN+ +W+EVT  E G 
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT-REDGV  482

Query  482  KGRRETNTMPQWAGSCWYFLRFIDPKNPDQLASPEKLDKWLPVDIYIGGAEHAVLHLLYA  541
            KGRRETNTMPQWAGS WY+LR+IDP N ++LA  E L +WLPVDIY+GGAEHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKFLYDIGVVPTKEPFQKLYNQGMILG------------------------------  571
            RFWHK LYD+GVVPTKEPFQKL+NQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---ENNEKMSKSRGNVVNPDEIVASHGADTLRLYEMFMGPLDASIAWSESGLDGARRFLD  628
               +   KMSKS  NVVNPD++V   GADTLR+YEMFMGPLDASIAWSE GL+G+R+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RVWRLFIEENGELTGKVTEGAGETLERVYHETVMKVTENYEALRFNTGISQLMVFINEAY  688
            RV RL+       T  +TE  + +L++VY+ETV  VTE+ + ++FNT+I+QLMVF+N A 
Sbjct  663  RVYRLIT------TKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  689  KANELPREYMEGFVKLLSPVAPHLAEELWEKLGHEG-SIAYEAWPAYDESKLVDDEVEIV  747
            K + L  +Y  GFV+L++P APHL+EELW+ L   G SI+Y +WP+YDESKLV+++VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  748  VQLNGKVKAKLMVPADADKAALEQLAQADEKVKEQLEGKTIRKIIAVPGKLVNIVAN  804
            VQ++GKVKAKL+V+ D  +  L+++A A+EKV+ ++ GK I K+IAVP KLVNIV +
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

264) leuS in NC_011999


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  908 bits (3440),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 558/837 (67%), Positives = 676/837 (81%), Gaps = 44/837 (5%)

Query  3    FNHQTIEKKWQKYWLDNHTFKTTEDKDK-NFYALDMFPYPSGAGLHVGHPEGYTATDIIS  61
            ++H +IE KWQ +W DNHTFKT  D  K +FYALDMFPYPSGAGLHVGHPEGYTATDI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  62   RFKRMQGYNVLHPMGWDAFGLPAEQYAIDTGNDPAEFTEKNIATFKRQIQELGFSYDWER  121
            RFKR QG NVLHPMGWDAFGLPAEQYA+DTGNDPAEFT  NIA FKRQI+ LGFSYDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  122  EINTTDPEYYKWTQWIFIQLYKKGLAYVDEVAVNWCPALGTVLSNEEVI-DGVSERGGHP  180
            E+NTTDP+YYKWTQWIF +LY KGLAY  EV+VNW   LGT ++NEEV+ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  181  VIRKPMRQWVLKITeyadrlledleeldwpeslKDMQRNWIGRSEGAEVAFEVENLDHSF  240
            V+RKPMRQW+LKIT YA+RLLEDLEE+DWPES+KDMQRNWIG+S GA+V+F V + D  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  KVFTTRPDTIYGATYAVLSPEHELVAAITSEEQAEAVKAYQEQAARKSDLERTDLAKDKT  300
             VFTTRPDT++GATYAVL+PEH LV AIT+ +QAEAV  Y+ QA+ KSDL RTDLAK+KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  301  GVFTGSYAINPFNGERMPIWISDYVLASYGTGAIMAVPAHDERDFEFAKQFGLDIKPVIE  360
            GV TGSYAINP NG  MP+WI+DYVLASYGTGAIMAVPAHDERD EFAKQF LDI PV+E
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  361  GGD-NTSAYTGDGAHINSGELDGLNKEEGIRRAIELLEAKGIGEKKVSYKLRDWLFSRQR  419
            GG+ + +A+T DG HINS+ LDGL+K  +I + +E LEA G+G+ +V+Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  420  YWGEPIPVITWEDGSMTTVPEEELPLMLPKTEHIKPSGTGESPLANIDEFVNVTDPVTGM  479
            YWGEPIP+I WEDG+ T+VPE ELPL+LP T +I+PSGTGESPLAN+ + ++VT    G+
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRE-DGV  482

Query  480  KGRRETNTMPQWAGSCWYYLRYIDPKNSDMIADPELLKKWLPVDLYIGGAEHAVLHLLYA  539
            KGRRETNTMPQWAGS WYYLRYIDP N++ +AD ELLK+WLPVD+Y+GGAEHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  540  RFWHKVLYDLGVVHTKEPFQKLFNQGMILG------------------------------  569
            RFWHKVLYDLGVV TKEPFQKLFNQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  570  ---EGNEKMSKSKGNVVNPDDVVASHGADTLRLYEMFMGPLDASIAWSTNGLDGARRFLD  626
               ++  KMSKS  NVVNPDDVV   GADTLR+YEMFMGPLDASIAWS +GL+G+R+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  627  RVYRLLVNEDGTLSEKITEQPVGSMEKVYHQTVKKVTDDYETLGFNTAISQMMVFINEGY  686
            RVYRL+   +      ITE+  G+++KVY++TVK VT++ + + FNTAI+Q+MVF+N + 
Sbjct  663  RVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  687  KSEQLNIDHIRGFVKLLNPIAPHITEELWEKLGGT-ESITYEAWPVYDESKLVDSEVEIV  745
            K ++L  D  +GFV+L+ P+APH+ EELW+ L ++ ESI+Y +WP YDESKLV+++VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  746  IQVNGKLKQKATIAKDMDKSEMETFALSLEAVQTAIEGKTVRKVIAVPNKLVNIVAN  802
            +Q++GK+K K  +AKD+ + E++  AL+ E VQ+ I GK + KVIAVPNKLVNIV +
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

265) leuS in NC_002570


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  907 bits (3436),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 564/839 (68%), Positives = 665/839 (80%), Gaps = 44/839 (5%)

Query  3    FSHREIESKWQKYWEENKTFKTEEDETREKFYALDMFPYPSGAGLHVGHPEGYTATDILS  62
            + H  IE+KWQ +W +N TFKT  D ++ KFYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMKRMQGYNVLHPMGWDAFGLPAEQYAIDTGNSPAEFTEKNINTFRRQIKSLGFSYDWDR  122
            R KR QG NVLHPMGWDAFGLPAEQYA+DTGN PAEFT  NI  F+RQI++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVNTTDPDYYKWTQWIFIQLYNKGLAYIDEVAVNWCPALGTVLANEEVI-DGKSERGGHP  181
            EVNTTDP+YYKWTQWIF +LY+KGLAY  EV+VNW   LGT +ANEEV+ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRPMKQWMLKITEYAdrlledleeldWPESIKDMQRNWIGRSEGAEVTFSVDGHDDTI  241
            V R+PM+QWMLKIT YA+RLLEDLEE+DWPESIKDMQRNWIG+S GA+VTF V + D  +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  TVFTTRPDTLFGATYMVLAPEHKLVDAITTSEQKQAVESYKKEVATKSDLERTELAKEKT  301
            TVFTTRPDTLFGATY VLAPEH LVDAITTS+Q +AV  YK++ + KSDL RT+LAKEKT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAINPVNGEKVPIWIADYVLVSYGTGAIMAVPAHDERDYEFAKTFDLPIKEVVS  361
            GV TG+YAINPVNG  +P+WIADYVL SYGTGAIMAVPAHDERD EFAK F+L I  V+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGVIEQEAYTGDGPHVNSEFLNGLSKEEAIEKMIQWLEAEKKGTKKVTYRLRDWLFSRQR  421
            GG +E+ A+T DG H+NS+FL+GL K  AI KM++WLEAE  G  +VTYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPVIHWEDGTMSTVPEDELPLELPKMSEIKPSGTGESPLANATDWLEVVDPVTGK  481
            YWGEPIP+IHWEDGT ++VPE ELPL LP   +I+PSGTGESPLAN TDWLEV     G 
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRE-DGV  482

Query  482  KGRRETNTMPQWAGSCWYYLRYIDPDNERMIADPEKLKKWLPVDIYIGGAEHAVLHLLYA  541
            KGRRETNTMPQWAGS WYYLRYIDP+N   +AD E LK+WLPVDIY+GGAEHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKVLYDLGVVPTKEPFQKLYNQGMILG------------------------------  571
            RFWHKVLYDLGVVPTKEPFQKL+NQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---ENNEKMSKSKGNVVNPDDIIDSHGADTLRLYEMFMGPLDASIAWSTTGLDGARRFLD  628
               +   KMSKS  NVVNPDD+++  GADTLR+YEMFMGPLDASIAWS  GL+G+R+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RVWRLLVDENTEEKSSKIVNGEGSPELKRAYHQTVKKVTEDFEELRFNVGISQLMVYVNE  688
            RV RL+        ++K +  E S  L + Y++TVK VTE+ ++++FN +I+QLMV+VN 
Sbjct  663  RVYRLI--------TTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNA  714

Query  689  AYKQEELPLDQAEGFVKLLSPVAPHLAEELWSKLGHEG-TIAYEPWPTYDEAFLVEDEVE  747
            A K++ L  D A GFV+L++P APHL+EELW  L   G +I+Y PWP+YDE+ LVE++VE
Sbjct  715  ANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVE  774

Query  748  IVVQHNGkvrakvvvakdatkEQMEEAALANERVKESIDGKTVRKVIVVPGKLVNIVAN  806
            IVVQ +GKV+AK+VVAKD ++E+++E ALANE+V+  I GK + KVI VP KLVNIV +
Sbjct  775  IVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

266) leuS in NC_021362


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  907 bits (3435),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 565/837 (68%), Positives = 668/837 (80%), Gaps = 42/837 (5%)

Query  3    FDHQTIEKKWQDYWLKNKTFATREDKSKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  62
            +DH +IE KWQ +W  N TF T  D SKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMKRMQGYNVLHPMGWDAFGLPAEQYALDTGNDPAVFTEQNIDNFRRQIRALGFSYDWDR  122
            R KR QG NVLHPMGWDAFGLPAEQYA+DTGNDPA FT +NI NF+RQI ALGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVNTTDPDYYKWTQWIFLKLYEKGLAYVDEVPVNWCPALGTVLANEEVI-DGKSERGGHP  181
            EVNTTDP+YYKWTQWIF KLYEKGLAY  EVPVNW   LGT +ANEEV+ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRPMKQWMLKITAYAdrlledleeldWPESIKEMQRNWIGRSEGAHVHFAVDGTDEMF  241
            V R+PM+QWMLKITAYA+RLLEDLEE+DWPESIK+MQRNWIG+S GA+V F V +TD  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  TVFTTRPDTLFGATYAVLAPEHDLVQKITTPEQQDAVDAYIEEVQSKSDLERTDLAKTKT  301
            TVFTTRPDTLFGATYAVLAPEH LV+ ITT++Q +AV  Y  +   KSDL RTDLAK KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAVNPANGEKIPVWIADYVLATYGTGAVMAVPAHDERDHEFASAFGLPIKEVVK  361
            GV TG+YA+NP NG  +PVWIADYVLA+YGTGA+MAVPAHDERD EFA  F L I  V+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGDVEKEAYTGDGEHIHSDFLNGLDKAAAIEKMIQWLEENGKGEKKVTYRLRDWLFSRQR  421
            GG+VE  A+T DG HI+SDFL+GLDKA+AI KM++WLE +G G+ +VTYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPVIHWEDGTSTPVpeeelplilpKTSEIKPSGTGESPLANIKEWVEVTDPETGK  481
            YWGEPIP+IHWEDGTST+VPE ELPL+LP T +I+PSGTGESPLAN+ +W+EVT  E G 
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT-REDGV  482

Query  482  KGRRETNTMPQWAGSCWYFLRYIDPKNPNELASPEKLQEWLPVDMYIGGAEHAVLHLLYA  541
            KGRRETNTMPQWAGS WY+LRYIDP N + LA  E L++WLPVD+Y+GGAEHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKFLYDIGVVPTKEPFKQLYNQGMILG------------------------------  571
            RFWHK LYD+GVVPTKEPF++L+NQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---ENNEKMSKSKGNVVNPDEIVETHGADTLRLYEMFMGPLDASIAWSTTGLDGARRFLD  628
               +   KMSKS  NVVNPD++VE  GADTLR+YEMFMGPLDASIAWS  GL+G+R+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RVWRLFIDDNGGLNEKIVEGAGETLERVYHETVMKVTDHFEGLRFNTGISQLMVFINEAY  688
            RV RL+   +      I E  + +L++VY+ETV  VT++ + ++FNT+I+QLMVF+N A 
Sbjct  663  RVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  689  KADQLPKEYMEGFVKLLSPVAPHLAEELWSRL-GHEETITYEAWPVYDEAKLVDDEVEIV  747
            K D+L  +Y  GFV+L++P APHL+EELW  L +  E+I+Y +WP YDE+KLV+++VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  748  VQLNGKVKAKLNVPADADKEQLEELAKNNEKVKEQLEGKTIRKVIAVPGKLVNIVAN  804
            VQ++GKVKAKL V+ D  +E+L+E+A  NEKV+ ++ GK I KVIAVP KLVNIV +
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

267) leuS in NC_008525


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  906 bits (3432),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 534/814 (66%), Positives = 659/814 (81%), Gaps = 43/814 (5%)

Query  3    YNHKDIEQKWQQFWSDNETFKTVEDADKPKYYALDMFPYPSGQGLHVGHPEGYTATDIMS  62
            Y+H  IE KWQ FW+DN+TFKT  DA KPK+YALDMFPYPSG GLHVGHPEGYTATDI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMKRMQGYKVLHPMGWDAFGLPAEQYAMKTGNNPRDFTAKNIQNFKRQIQSLGFSYDWSR  122
            R KR QG +VLHPMGWDAFGLPAEQYAM TGN+P +FTA NI NFKRQI++LGFSYDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVNTTDPAYYKWTQWIFEQLYKKGLAYEKETLVNWAPDLMGGTVVANEEVV-DGKTERGG  181
            EVNTTDP YYKWTQWIF +LY KGLAYE E  VNW  +L  GT +ANEEV+ DG +ERGG
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEEL--GTAIANEEVLPDGTSERGG  181

Query  182  FPVYRKPMKQWILKITAYADRLIDDLDLVDWPDSIKEMQKNWIGRSVGASVFFNVEDSEK  241
            +PV RKPM+QW+LKITAYA+RL++DL+ VDWP+SIK+MQ+NWIG+S GA+V F+V D++K
Sbjct  182  YPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDK  241

Query  242  QIEVFTTRPDTLFGATYLVISPEHDLVDQITTPESkaaveeykkavatkSDLERTDLNKD  301
            ++ VFTTRPDTLFGATY V++PEH LVD ITT++   AV +YK+  + KSDL RTDL K+
Sbjct  242  DFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKE  301

Query  302  KTGVFTGAYAVNPVNGKKIPVWISDYVLASYGTGAVMAVPAHDGRDYEFAKKFKIDMVPV  361
            KTGV TG+YA+NPVNGK +PVWI+DYVLASYGTGA+MAVPAHD RD EFAK+F++D++PV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  362  YEGGNLEDGVLDSEGGLINSGFLDGMDKQTAIDTMISWLEEHGVGHKKVNYRLRDWVFSR  421
             EGGN+E++ +  +G  INS+FLDG+DK +AI  M+ WLE +GVG+ +V YRLRDW+FSR
Sbjct  362  LEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSR  421

Query  422  QRYWGEPIPVIHWEDGETTLIPEDELPLRLPAATDIRPSGTGESPLANLDDWVNVVDENG  481
            QRYWGEPIP+IHWEDG +T +PE ELPL LP + DIRPSGTGESPLAN+ DW++V  E+G
Sbjct  422  QRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDG  481

Query  482  RKGRRETNTMPQWAGSSWYFLRYVDPKNDQKIADEDLLKEWLPVDLYVGGAEHAVLHLLY  541
             KGRRETNTMPQWAGSSWY+LRY+DP N +K+ADE+LLK+WLPVD+YVGGAEHAVLHLLY
Sbjct  482  VKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLY  541

Query  542  ARFWHKVLYDLGVVPTKEPFQKLVNQGMILGSN---------------------------  574
            ARFWHKVLYDLGVVPTKEPFQKL NQGMILG++                           
Sbjct  542  ARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETG  601

Query  575  ------HEKMSKSKGNVVNPDDIVERFGADTLRLYEMFMGPLTESVAWSEDGLNGSRKWI  628
                    KMSKS  NVVNPDD+VE++GADTLR+YEMFMGPL  S+AWSE+GL+GSRK +
Sbjct  602  EELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFL  661

Query  629  DRVWRLMIDDENQLRDHIVTENDGSLDMIYNQTVKKVTDDYENMRFNTAISQMMVFVNEA  688
            DRV RL+   E      I  EN G+LD +YN+TVK VT++ ++M+FNTAI+Q+MVFVN A
Sbjct  662  DRVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAA  715

Query  689  YKADKLPAVYMEGLVKMLAPIIPHVAEELWSLLGHEG-GISYAEWPTYDESKLVEATVQV  747
             K DKL + Y  G+V+++AP+ PH++EELW  L   G +ISY  WP+YDESKLVE  V++
Sbjct  716  NKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEI  775

Query  748  ILQVNGKVRSKITVDKDIAKEELEKLALADAKIQ  781
            ++Q++GKV++K+ V KD+++EEL+ +ALA+ K+Q
Sbjct  776  VVQIKGKVKAKLVVAKDLSREELQEVALANEKVQ  809

268) SLGD_01172 in NC_013893


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  905 bits (3430),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 555/837 (67%), Positives = 680/837 (82%), Gaps = 42/837 (5%)

Query  3    YNHKIIEKKWQCFWLDNQTFKTSDNLGQKKFYALDMFPYPSGAGLHVGHPEGYTATDIIS  62
            Y+H  IE KWQ FW DN+TFKT+ + ++ KFYALDMFPYPSGAGLHVGHPEGYTATDI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRMQGYNVLHPMGWDAFGLPAEQYALDTGNDPRAFTKQNIQTFKRQIQELGFSYDWDR  122
            R+KR QG NVLHPMGWDAFGLPAEQYA+DTGNDP  FT +NI  FKRQI+ LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVNTTDPEYYKWTQWIFIQLYNKGLAYVDEVAVNWCPALGTVLSNEEVV-DGVSERGGHP  181
            EVNTTDP+YYKWTQWIF +LY+KGLAY  EV+VNW   LGT ++NEEV+ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VYRRPMKQWVLKITEYAdrlledlddldWPESIKDMQRNWIGRSEGARVSFKVEGENDTI  241
            V R+PM+QW+LKIT YA+RLLEDL+++DWPESIKDMQRNWIG+S GA V+FKV + +  +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  DVFTTRPDTIFGTTFLVLSPEHALVEKITTTEKFEEVKKYQEAASKKSDLERTDLAKDKS  301
             VFTTRPDT+FG+T+ VL+PEHALV+ ITT+++ E V  Y+  AS KSDL RTDLAK+K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAINPLSGEKLPIWIADYVLSSYGTGAVMAVPAHDERDHEFAVKFNLPIIEVIA  361
            GV TG+YAINP++G  +P+WIADYVL+SYGTGA+MAVPAHDERD EFA +FNL II V+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGDVQKEAYTGAGEHVNSGDLDGLNNEQAIAKAIELLEAKGAGEKKVNYKLRDWLFSRQR  421
            GG+V+  A+T  G H+NS+ LDGL++  AIAK +E LEA G G+ +V Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPIIHWEDGTMTTVpeeelplllpeTDEIKPSGTGESPLANIDDFVNVVDEETGM  481
            YWGEPIPIIHWEDGT T+VPE ELPL+LP T +I+PSGTGESPLAN+ D ++V  E+ G+
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED-GV  482

Query  482  RGRRETNTMPQWAGSCWYYLRYIDPHNEQMLADPEKLKHWLPVDLYIGGVEHAVLHLLYA  541
            +GRRETNTMPQWAGS WYYLRYIDPHN + LAD E LK+WLPVD+Y+GG EHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKVLYDLGVVPTKEPFQKLFNQGMILG------------------------------  571
            RFWHKVLYDLGVVPTKEPFQKLFNQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---EGNEKMSKSKGNVVNPDDIVNSHGADTLRLYEMFMGPLDAAIAWSENGLDGSRRFLD  628
               ++  KMSKS  NVVNPDD+V+  GADTLR+YEMFMGPLDA+IAWSE+GL+GSR+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RVWRLFINEDDSLSQKFVESNNKSLDKVYNQTVKKVTEDFDTLNFNTAISQLMVFINECY  688
            RV RL+   +      + E N+ +LDKVYN+TVK VTE+ D ++FNTAI+QLMVF+N   
Sbjct  663  RVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  689  KVDEIYQPYAEGFVKMLAPIAPHIGEELWQKL-GHDETITYQPWPTYNETLLVDSEVEIV  747
            K D ++  YA GFV+++AP+APH+GEELWQ L + +E+I+Y PWP+Y+E+ LV+++VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  748  VQVNGKVRAKLTIPKELSKEEMQELALENENVKMAIDGKEIKKVIAVPQKLVNIVAK  804
            VQ++GKV+AKL ++K+LS+EE+QE+AL NE+V+  I GK+I KVIAVP+KLVNIV K
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

269) leuS in NC_017353


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  905 bits (3430),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 554/837 (67%), Positives = 680/837 (82%), Gaps = 42/837 (5%)

Query  3    YNHKIIEKKWQCFWLDNQTFKTSDNLGQKKFYALDMFPYPSGAGLHVGHPEGYTATDIIS  62
            Y+H  IE KWQ FW DN+TFKT+ + ++ KFYALDMFPYPSGAGLHVGHPEGYTATDI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRMQGYNVLHPMGWDAFGLPAEQYALDTGNDPRAFTKQNIQTFKRQIQELGFSYDWDR  122
            R+KR QG NVLHPMGWDAFGLPAEQYA+DTGNDP  FT +NI  FKRQI+ LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVNTTDPEYYKWTQWIFIQLYNKGLAYVDEVAVNWCPALGTVLSNEEVV-DGVSERGGHP  181
            EVNTTDP+YYKWTQWIF +LY+KGLAY  EV+VNW   LGT ++NEEV+ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VYRRPMKQWVLKITEYAdrlledlddldWPESIKDMQRNWVGRSEGARVSFKVEGENDTI  241
            V R+PM+QW+LKIT YA+RLLEDL+++DWPESIKDMQRNW+G+S GA V+FKV + +  +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  DVFTTRPDTIFGTTFLVLSPEHALVEKITTTEKFEEVKKYQEAASKKSDLERTDLAKDKS  301
             VFTTRPDT+FG+T+ VL+PEHALV+ ITT+++ E V  Y+  AS KSDL RTDLAK+K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAINPLSGEKLPIWIADYVLSSYGTGAVMAVPAHDERDHEFAVKFNLPIIEVIA  361
            GV TG+YAINP++G  +P+WIADYVL+SYGTGA+MAVPAHDERD EFA +FNL II V+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGDVQKEAYTGAGEHVNSGDLDGLNNEQAIAKAIELLEAKGAGEKKVNYKLRDWLFSRQR  421
            GG+V+  A+T  G H+NS+ LDGL++  AIAK +E LEA G G+ +V Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPIIHWEDGTMTTVpeeelplllpeTDEIKPSGTGESPLANIDDFVNVVDEETGM  481
            YWGEPIPIIHWEDGT T+VPE ELPL+LP T +I+PSGTGESPLAN+ D ++V  E+ G+
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED-GV  482

Query  482  RGRRETNTMPQWAGSCWYYLRYIDPHNEQMLADPEKLKHWLPVDLYIGGVEHAVLHLLYA  541
            +GRRETNTMPQWAGS WYYLRYIDPHN + LAD E LK+WLPVD+Y+GG EHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKVLYDLGVVPTKEPFQKLFNQGMILG------------------------------  571
            RFWHKVLYDLGVVPTKEPFQKLFNQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---EGNEKMSKSKGNVVNPDDIVNSHGADTLRLYEMFMGPLDAAIAWSENGLDGSRRFLD  628
               ++  KMSKS  NVVNPDD+V+  GADTLR+YEMFMGPLDA+IAWSE+GL+GSR+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RVWRLFINEDDSLSQKFVESNNKSLDKVYNQTVKKVTEDFDTLNFNTAISQLMVFINECY  688
            RV RL+   +      + E N+ +LDKVYN+TVK VTE+ D ++FNTAI+QLMVF+N   
Sbjct  663  RVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  689  KVDEIYQPYAEGFVKMLAPIAPHIGEELWQKL-GHDETITYQPWPTYNETLLVDSEVEIV  747
            K D ++  YA GFV+++AP+APH+GEELWQ L + +E+I+Y PWP+Y+E+ LV+++VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  748  VQVNGKVRAKLTIPKELSKEEMQELALENENVKMAIDGKEIKKVIAVPQKLVNIVAK  804
            VQ++GKV+AKL ++K+LS+EE+QE+AL NE+V+  I GK+I KVIAVP+KLVNIV K
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

270) leuS in NC_017568


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  905 bits (3429),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 541/837 (65%), Positives = 673/837 (81%), Gaps = 43/837 (5%)

Query  10   YNHQEVEKKWQTYWLENKTFKTEDNIGQKKFYALDMFPYPSGAGLHVGHPEGYTATDILS  69
            Y+H  +E KWQ++W +N TFKT  + ++ KFYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  70   RYKRMQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTKRNIQTFKRQIQELGFSYDWDR  129
            R+KR QG NVLHPMGWDAFGLPAEQYA+DTGNDPAEFT  NI  FKRQI+ LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  130  EVSTTDPEYYKWTQWIFIQLYKKGLAYIDEIPVNWCEALGTVLSNEEVV-DGVSERGGYP  188
            EV+TTDP+YYKWTQWIF +LY KGLAY  E+PVNW E LGT ++NEEV+ DG SERGGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  189  VVRRPMKQWVLKITEYADRLLEDLDTLDWPESIKDMQRNWIGRSEGAKVNFKVENINTPI  248
            VVR+PM+QW+LKIT YA+RLLEDL+ +DWPESIKDMQRNWIG+S GA+V FKV + +  +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  249  EVFTTRPDTIYGATFLVLSPEHTLVNRITTPQQYEKVKHYQDEAAKKSDLERTDLAKEKT  308
             VFTTRPDT++GAT+ VL+PEH+LV+ ITT++Q E V +Y+ +A+ KSDL RTDLAKEKT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  309  GVFTGAYAIHPFTGKQVPIWIADYVLASYGTGAVMAVPAHDERDYEFATTFDLPVVTVIE  368
            GV TG+YAI+P  GK++P+WIADYVLASYGTGA+MAVPAHDERD EFA  F+L ++ V+E
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  369  -NDAETPYYTGDGAHVQSGELDGlnneaaiakaielleakGLGEKKVNYKLRDWLFSRQR  427
              + E + +T DG H++S+ LDGL++ +AIAK +E LEA G+G+ +V Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  428  YWGEPIPIIHWEDGSMTTVPENELPLLLPKTDEIKPSGTGESPLANIDDFVNVVDPETGM  487
            YWGEPIPIIHWEDG+ T+VPE+ELPL+LP T +I+PSGTGESPLAN+ D ++V   E G+
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT-REDGV  482

Query  488  KGRRETNTMPQWAGSCWYYLRYIDPKNDQMLADPEKLKHWLPVDLYIGGVEHAVLHLLYA  547
            KGRRETNTMPQWAGS WYYLRYIDP N + LAD E LK+WLPVD+Y+GG EHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  548  RFWHKVLYDLGIVPTSEPFQKLFNQGMILG------------------------------  577
            RFWHKVLYDLG+VPT EPFQKLFNQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  578  ---EGNEKMSKSKGNVVNPDDIVRSHGADTLRLYEMFMGPLEASIAWSENGLDGSRRFLD  634
               ++  KMSKS  NVVNPDD+V   GADTLR+YEMFMGPL+ASIAWSE+GL+GSR+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  635  RVWRLFVTEDSQLTDKVIEGDTPALQTVYHQTVKKVTEDFESLSFNTAISQLMVFINECY  694
            RV RL+ T +      + E ++ AL+ VY++TVK VTE+ + + FNTAI+QLMVF+N   
Sbjct  663  RVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  695  KADNISKAYAEGFVKMLAPIAPHVGEELWSIL-GHDTTITYQPWPSFDPSLLEEDVVEIV  753
            K D++   YA GFV+++AP+APH+GEELW  L + + +I+Y PWPS+D S L E+ VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  754  VQVNGKVRAKIEIPKDMSKADMEATALANDNIKAAVEGKDVKKVIAVPQKLVNIVAK  810
            VQ++GKV+AK+ ++KD+S+ +++  ALAN++++A + GKD+ KVIAVP+KLVNIV K
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

271) SPSINT_1524 in NC_014925


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  904 bits (3423),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 539/837 (65%), Positives = 672/837 (81%), Gaps = 43/837 (5%)

Query  10   YNHQEVEKKWQTYWLENKTFKTEDNIGQKKFYALDMFPYPSGAGLHVGHPEGYTATDILS  69
            Y+H  +E KWQ++W +N TFKT  + ++ KFYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  70   RYKRMQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTKRNIQTFKRQIQELGFSYDWDR  129
            R+KR QG NVLHPMGWDAFGLPAEQYA+DTGNDPAEFT  NI  FKRQI+ LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  130  EVSTTDPEYYKWTQWIFIQLYKKGLAYIDEIPVNWCEALGTVLSNEEVV-DGVSERGGYP  188
            EV+TTDP+YYKWTQWIF +LY KGLAY  E+PVNW E LGT ++NEEV+ DG SERGGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  189  VVRRPMKQWVLKITEYADRLLEDLDTLDWPESIKDMQRNWIGRSEGAKVNFKVENINTPI  248
            VVR+PM+QW+LKIT YA+RLLEDL+ +DWPESIKDMQRNWIG+S GA+V FKV + +  +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  249  EVFTTRPDTIYGATFLVLSPEHTLVNRITTPQQYEKVKHYQDEAAKKSDLERTDLAKEKT  308
             VFTTRPDT++GAT+ VL+PEH+LV+ ITT++Q E V +Y+ +A+ KSDL RTDLAKEKT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  309  GVFTGAYAIHPFTGKQVPIWIADYVLASYGTGAVMAVPAHDERDYEFATTFDLPVVTVIE  368
            GV TG+YAI+P  GK++P+WIADYVLASYGTGA+MAVPAHDERD EFA  F+L ++ V+E
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  369  -NDAETPYYTGDGAHVQSGELDGlnneaaiakaielleakGLGEKKVNYKLRDWLFSRQR  427
              + E + +T DG H++S+ LDGL++ +AIAK +E LEA G+G+ +V Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  428  YWGEPIPIIHWEDGSMTTVPENELPLLLPKTDEIKPSGTGESPLANIDDFVNVVDPETGM  487
            YWGEPIPIIHWEDG+ T+VPE+ELPL+LP T +I+PSGTGESPLAN+ D ++V   E G+
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT-REDGV  482

Query  488  KGRRETNTMPQWAGSCWYYLRYIDPKNDQMLADPEKLKHWLPVDLYIGGVEHAVLHLLYA  547
            KGRRETNTMPQWAGS WYYLRYIDP N + LAD E LK+WLPVD+Y+GG EHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  548  RFWHKVLYDLGIVPTSEPFQKLFNQGMILG------------------------------  577
            RFWHKVLYDLG+VPT EPFQKLFNQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  578  ---EGNEKMSKSKGNVVNPDDIVRSHGADTLRLYEMFMGPLEASIAWSENGLDGSRRFLD  634
               ++  KMSKS  NVVNPDD+V   GADTLR+YEMFMGPL+ASIAWSE+GL+GSR+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  635  RVWRLFVTEDSQLTDKVIEGDTPTLQTAYHQTVKKVTEDFESLSFNTAISQLMVFINECY  694
            RV RL+ T +      + E ++ +L+  Y++TVK VTE+ + + FNTAI+QLMVF+N   
Sbjct  663  RVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  695  KADNISKAYAEGFVKMLAPIAPHVGEELWSIL-GHDTTITYQPWPSFDPSLLEEDVVEIV  753
            K D++   YA GFV+++AP+APH+GEELW  L + + +I+Y PWPS+D S L E+ VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  754  VQVNGKVRAKIEIPKDMSKADMEATALANDNIKAAVEGKDVKKVIAVPQKLVNIVAK  810
            VQ++GKV+AK+ ++KD+S+ +++  ALAN++++A + GKD+ KVIAVP+KLVNIV K
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

272) Geoth_0822 in NC_015660


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  903 bits (3419),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 563/838 (68%), Positives = 667/838 (80%), Gaps = 43/838 (5%)

Query  3    FNHREIEKKWQDYWEKNKTFKTVDDDDKPKFYVLDMFPYPSGAGLHVGHPEGYTATDILA  62
            ++H  IE KWQ +W  N TFKT  D  KPKFY LDMFPYPSGAGLHVGHPEGYTATDIL+
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMKRMQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTEKNINTFRRQIKSLGFSYDWDR  122
            R KR QG NVLHPMGWDAFGLPAEQYA+DTGNDPAEFT  NI  F+RQI++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EINTTDPNYYKWTQWIFLKLYEKGLAYIDEVPVNWCPALGTVLANEEVI-NGRSERGGHP  181
            E+NTTDPNYYKWTQWIF KLYEKGLAY  EVPVNW   LGT +ANEEV+ +G SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VIRKPMRQWMLRITAYAdrlledleeldWPESIKEMQRNWIGRSEGAEIRFEVDGHNETF  241
            V+RKPMRQWML+ITAYA+RLLEDLEE+DWPESIK+MQRNWIG+S GA++ F V + +  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  TVFTTRPDTLFGATYTVLAPEHPLVEKITTPEQKAAVEAYLDAIKSKSDLERTDLAKEKT  301
            TVFTTRPDTLFGATY+VLAPEH+LV+ ITT++Q  AV  Y      KSDL RTDLAKEKT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAIHPVTGEKLPIWIADYVLMSYGTGAIMAVPAHDERDYEFAKKFNLPIKEVVA  361
            GV TG+YAI+PV G  +P+WIADYVL SYGTGAIMAVPAHDERD EFAK+FNL I  V+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGDIAKEAYTGDGEHINSDFLNGLNKEEAIKKMIEWLEANGKGQKKVTYRLRDWLFSRQR  421
            GG++   A+T DG HINSDFL+GL+K  AI KM+EWLEA+G G+ +VTYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPIIHWEDGTMTPVpeeelplklpkTDQIRPSGTGESPLANIEEWVNVIDPKTGK  481
            YWGEPIPIIHWEDGT T+VPE ELPL LP T +IRPSGTGESPLAN+ +W++V     G 
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT-REDGV  482

Query  482  KGRRETNTMPQWAGSCWYYLRYIDPHNDKQLADPEKLKKWLPVDVYIGGAEHAVLHLLYA  541
            KGRRETNTMPQWAGS WYYLRYIDPHN  +LAD E LK+WLPVD+Y+GGAEHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKFLYDIGVVPTKEPFQKLFNQGMILG------------------------------  571
            RFWHK LYD+GVVPTKEPFQKLFNQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---ENNEKMSKSRGNVVNPDDIIESHGADTLRLYEMFMGPLEASIAWSTKGLDGARRFLE  628
               +   KMSKS  NVVNPDD++E  GADTLR+YEMFMGPL+ASIAWS  GL+G+R+FL+
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RVWRLFVDENGELNPKIVDNPETDTLERVYHQTVKKVTEDYEALRFNTAISQLMVFINEA  688
            RV RL       +  K + + ++++L++VY++TVK VTE+ + ++FNTAI+QLMVF+N A
Sbjct  663  RVYRL-------ITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAA  715

Query  689  YKAPVLPKKYMEGFVKLLSPVCPHIGEELWEKL-GHNNTIAYEPWPTYDEAKLveeevei  747
             K   L   Y  GFV+L++P  PH+GEELW+ L +  ++I+Y PWP+YDE+KLVE++VEI
Sbjct  716  NKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEI  775

Query  748  vvqvNGKVRAKLHVRADLSKEELEQAAMQDEKVQEHIAGKTVRKVITVPGKLVNIVAN  805
            VVQ++GKV+AKL V  DLS+EEL++ A+ +EKVQ +IAGK + KVI+VP KLVNIV +
Sbjct  776  VVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

273) GY4MC1_0754 in NC_014650


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  903 bits (3419),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 563/838 (68%), Positives = 667/838 (80%), Gaps = 43/838 (5%)

Query  3    FNHREIEKKWQDYWEKNKTFKTVDDDDKPKFYVLDMFPYPSGAGLHVGHPEGYTATDILA  62
            ++H  IE KWQ +W  N TFKT  D  KPKFY LDMFPYPSGAGLHVGHPEGYTATDIL+
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMKRMQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTEKNINTFRRQIKSLGFSYDWDR  122
            R KR QG NVLHPMGWDAFGLPAEQYA+DTGNDPAEFT  NI  F+RQI++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EINTTDPNYYKWTQWIFLKLYEKGLAYIDEVPVNWCPALGTVLANEEVI-NGRSERGGHP  181
            E+NTTDPNYYKWTQWIF KLYEKGLAY  EVPVNW   LGT +ANEEV+ +G SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VIRKPMRQWMLRITAYAdrlledleeldWPESIKEMQRNWIGRSEGAEIRFEVDGHNETF  241
            V+RKPMRQWML+ITAYA+RLLEDLEE+DWPESIK+MQRNWIG+S GA++ F V + +  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  TVFTTRPDTLFGATYTVLAPEHPLVEKITTPEQKAAVEAYLDAIKSKSDLERTDLAKEKT  301
            TVFTTRPDTLFGATY+VLAPEH+LV+ ITT++Q  AV  Y      KSDL RTDLAKEKT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAIHPVTGEKLPIWIADYVLMSYGTGAIMAVPAHDERDYEFAKKFNLPIKEVVA  361
            GV TG+YAI+PV G  +P+WIADYVL SYGTGAIMAVPAHDERD EFAK+FNL I  V+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGDIAKEAYTGDGEHINSDFLNGLNKEEAIKKMIEWLEANGKGQKKVTYRLRDWLFSRQR  421
            GG++   A+T DG HINSDFL+GL+K  AI KM+EWLEA+G G+ +VTYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPIIHWEDGTMTPVpeeelplklpkTDQIRPSGTGESPLANIEEWVNVIDPKTGK  481
            YWGEPIPIIHWEDGT T+VPE ELPL LP T +IRPSGTGESPLAN+ +W++V     G 
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT-REDGV  482

Query  482  KGRRETNTMPQWAGSCWYYLRYIDPHNDKQLADPEKLKKWLPVDVYIGGAEHAVLHLLYA  541
            KGRRETNTMPQWAGS WYYLRYIDPHN  +LAD E LK+WLPVD+Y+GGAEHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKFLYDIGVVPTKEPFQKLFNQGMILG------------------------------  571
            RFWHK LYD+GVVPTKEPFQKLFNQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---ENNEKMSKSRGNVVNPDDIIESHGADTLRLYEMFMGPLEASIAWSTKGLDGARRFLE  628
               +   KMSKS  NVVNPDD++E  GADTLR+YEMFMGPL+ASIAWS  GL+G+R+FL+
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RVWRLFVDENGELNPKIVDNPETDTLERVYHQTVKKVTEDYEALRFNTAISQLMVFINEA  688
            RV RL       +  K + + ++++L++VY++TVK VTE+ + ++FNTAI+QLMVF+N A
Sbjct  663  RVYRL-------ITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAA  715

Query  689  YKAPVLPKKYMEGFVKLLSPVCPHIGEELWEKL-GHNNTIAYEPWPTYDEAKLveeevei  747
             K   L   Y  GFV+L++P  PH+GEELW+ L +  ++I+Y PWP+YDE+KLVE++VEI
Sbjct  716  NKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEI  775

Query  748  vvqvNGKVRAKLHVRADLSKEELEQAAMQDEKVQEHIAGKTVRKVITVPGKLVNIVAN  805
            VVQ++GKV+AKL V  DLS+EEL++ A+ +EKVQ +IAGK + KVI+VP KLVNIV +
Sbjct  776  VVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

274) leuS in NC_014724


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  903 bits (3421),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 520/822 (64%), Positives = 647/822 (79%), Gaps = 45/822 (5%)

Query  2    YNHKVVEKKWQDYWAKHDTFKTGTDPNKNNYYALDMFPFPSGKGLHVGHPEGYTATDIVA  61
            Y+H  +E KWQ +WA ++TFKTGTD++K ++YALDMFP+PSG GLHVGHPEGYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  62   RMKRAQGYNVLHPMGWDAFGLPTEQYALKTGEDPEVVTKNNIANFKRQLNKLGFSYDWDR  121
            R KRAQG NVLHPMGWDAFGLP+EQYA+ TG+DP   T +NIANFKRQ+N LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  122  EVTTSDPNYYKWTQWVFEQMYKNGLAYEAEVPVNWSPDLGTVVANEEVI-DGKTERGGYP  180
            EV T+DPNYYKWTQW+F ++Y +GLAYEAEVPVNW  +LGT +ANEEV+ DG +ERGGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  181  VYRKNMRQWMLKMTAYADRLLEDLDGLDWPEPVKEMQRNWIGRSVGAQVTFKIKGSDKTF  240
            V RK MRQWMLK+TAYA+RLLEDL+ +DWPE++K+MQRNWIG+S GA+VTFK+K++DK F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  DIFTTRPDTLFGCSYTVLAPENKLVQEITTDAHRDEVNAYIKKIESKSDLERTDLNKNKT  300
             +FTTRPDTLFG +Y+VLAPE+ LV+ ITT  + + V  Y ++   KSDL RTDL K+KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  301  GVFTGAYAINPVNGKEVPIWISDYVLASYGTGAVMAVPAHDDRDYAFATKFGLPINPVLE  360
            GV TG+YAINPVNGKE+P+WI+DYVLASYGTGA+MAVPAHD+RD  FA +F L I PVLE
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  361  GGDITKEAFTEDGPHINSEFLNGLNIEDAKKKMVDWLEDHNCGEKKVNYKLRDWDFSRQR  420
            GG++   AFTEDG HINS+FL+GL+   A  KMV+WLE +  G+ +V Y+LRDW FSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  421  YWGEPIPVIHWEDGETTLVPEDQLPLRLPHATDIKPSGTPESPLANLTDWVNVVDKNGRK  480
            YWGEPIP+IHWEDG +T VPE +LPL LP + DI+PSGT ESPLAN+TDW++V   +G K
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  481  GKRETNTMPNWAGSSWYYLRYVDPHNDKELADYDLLKQWLPVDLYIGGAEHAVRHLLYAR  540
            G+RETNTMP+WAGSSWYYLRY+DPHN   LAD +LLKQWLPVD+Y+GGAEHAV HLLYAR
Sbjct  484  GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYAR  543

Query  541  FWHKVLYDLGVVPTKEPFQRLYNQGLIL--------------------------------  568
            FWHKVLYDLGVVPTKEPFQ+L+NQG+IL                                
Sbjct  544  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEE  603

Query  569  --KNHEKMSKSKGNVVNPDDVIDEYGADSLRMYEMFMGPLDASIDWDDNGPASTKKFLDR  626
              +   KMSKS  NVVNPDDV+++YGAD+LR+YEMFMGPLDASI W ++G  +++KFLDR
Sbjct  604  LEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR  663

Query  627  VWRLFVNDLDLKAIPQERIVDKNDGELDKVYAETVKKVTEDFDALHFNTAISQMMVFINA  686
            V RL         I    I + N G LDKVY ETVK VTE+ D + FNTAI+Q+MVF+NA
Sbjct  664  VYRL---------ITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNA  714

Query  687  AQKAKTIPREYAEGFVKLLAPVAPHMMEEIWQVF-GHDESITYAKWPTYDPAKLVESTVE  745
            A+K   +  +YA GFV+L+AP APH+ EE+WQ + + +ESI+Y  WP+YD +KLVE+ VE
Sbjct  715  ANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVE  774

Query  746  IMVQVNGKLRGKFQAAKDADRDDVQKQAMTLPHVQKFLEGKD  787
            I+VQ++GK+++K+  AKD  R+++Q  A++   VQ  + GKD
Sbjct  775  IVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKD  816

275) leuS in NC_015214


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  902 bits (3417),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 520/822 (64%), Positives = 647/822 (79%), Gaps = 45/822 (5%)

Query  2    YNHKVVEKKWQDYWAKHDTFKTGTDPNKKNYYALDMFPFPSGKGLHVGHPEGYTATDIVA  61
            Y+H  +E KWQ +WA ++TFKTGTD++K ++YALDMFP+PSG GLHVGHPEGYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  62   RMKRAQGYNVLHPMGWDAFGLPTEQYALKTGEDPEVVTKNNIANFKRQLNKLGFSYDWDR  121
            R KRAQG NVLHPMGWDAFGLP+EQYA+ TG+DP   T +NIANFKRQ+N LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  122  EVTTSDPNYYKWTQWVFEQMYKNGLAYEAEVPVNWSPDLGTVVANEEVI-DGKTERGGYP  180
            EV T+DPNYYKWTQW+F ++Y +GLAYEAEVPVNW  +LGT +ANEEV+ DG +ERGGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  181  VYRKNMRQWMLKMTAYADRLLEDLDGLDWPEPVKEMQRNWIGRSVGAQVTFKIKGSDKTF  240
            V RK MRQWMLK+TAYA+RLLEDL+ +DWPE++K+MQRNWIG+S GA+VTFK+K++DK F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  DIFTTRPDTLFGCSYTVLAPENKLVQEITTDAHRDEVNAYIKKIESKSDLERTDLNKNKT  300
             +FTTRPDTLFG +Y+VLAPE+ LV+ ITT  + + V  Y ++   KSDL RTDL K+KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  301  GVFTGAYAINPVNGKEVPIWISDYVLASYGTGAVMAVPAHDDRDYAFATKFGLPINPVLE  360
            GV TG+YAINPVNGKE+P+WI+DYVLASYGTGA+MAVPAHD+RD  FA +F L I PVLE
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  361  GGDITKEAFTEDGPHINSEFLNGLNIEDAKKKMVDWLEDHNCGEKKVNYKLRDWDFSRQR  420
            GG++   AFTEDG HINS+FL+GL+   A  KMV+WLE +  G+ +V Y+LRDW FSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  421  YWGEPIPVIHWEDGETTLVPEDQLPLRLPHATDIKPSGTPESPLANLTDWVNVVDKNGRK  480
            YWGEPIP+IHWEDG +T VPE +LPL LP + DI+PSGT ESPLAN+TDW++V   +G K
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  481  GKRETNTMPNWAGSSWYYLRYVDPHNDKELADYDLLKQWLPVDLYIGGAEHAVRHLLYAR  540
            G+RETNTMP+WAGSSWYYLRY+DPHN   LAD +LLKQWLPVD+Y+GGAEHAV HLLYAR
Sbjct  484  GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYAR  543

Query  541  FWHKVLYDLGVVPTKEPFQRLYNQGLIL--------------------------------  568
            FWHKVLYDLGVVPTKEPFQ+L+NQG+IL                                
Sbjct  544  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEE  603

Query  569  --KNHEKMSKSKGNVVNPDDVIDEYGADSLRMYEMFMGPLDASIDWDDNGPASTKKFLDR  626
              +   KMSKS  NVVNPDDV+++YGAD+LR+YEMFMGPLDASI W ++G  +++KFLDR
Sbjct  604  LEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR  663

Query  627  VWRLFVNDLDLKAIPQERIVDKNDGELDKVYAETVKKVTEDFDALHFNTAISQMMVFINA  686
            V RL         I    I + N G LDKVY ETVK VTE+ D + FNTAI+Q+MVF+NA
Sbjct  664  VYRL---------ITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNA  714

Query  687  AQKAKTIPREYAEGFVKLLAPVAPHMMEEIWQVF-GHDESITYAKWPTYDPAKLVESTVE  745
            A+K   +  +YA GFV+L+AP APH+ EE+WQ + + +ESI+Y  WP+YD +KLVE+ VE
Sbjct  715  ANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVE  774

Query  746  IMVQVNGKLRGKFQAAKDADRDDVQKQAMTLPHVQKFLEGKD  787
            I+VQ++GK+++K+  AKD  R+++Q  A++   VQ  + GKD
Sbjct  775  IVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKD  816

276) leuS in NC_017470


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  902 bits (3417),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 521/822 (64%), Positives = 647/822 (79%), Gaps = 45/822 (5%)

Query  2    YNHKVVEKKWQDYWAKHDTFKTGTDPNKKNYYALDMFPFPSGKGLHVGHPEGYTATDIVA  61
            Y+H  +E KWQ +WA ++TFKTGTD++K ++YALDMFP+PSG GLHVGHPEGYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  62   RMKRAQGYNVLHPMGWDAFGLPTEQYALKTGEDPEVVTKNNIANFKRQLNKLGFSYDWDR  121
            R KRAQG NVLHPMGWDAFGLP+EQYA+ TG+DP   T +NIANFKRQ+N LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  122  EVTTSDPNYYKWTQWVFEQMYKNGLAYEAEVPVNWSPDLGTVVANEEVI-DGKTERGGYP  180
            EV T+DPNYYKWTQW+F ++Y +GLAYEAEVPVNW  +LGT +ANEEV+ DG +ERGGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  181  VYRKNMRQWMLKMTAYADRLLEDLDGLDWPEPVKEMQRNWIGRSVGAQVTFKIKGSDKTF  240
            V RK MRQWMLK+TAYA+RLLEDL+ +DWPE++K+MQRNWIG+S GA+VTFK+K++DK F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  DIFTTRPDTLFGCSYTVLAPENKLVQEITTDAHRDEVNAYIKKIESKSDLERTDLNKNKT  300
             +FTTRPDTLFG +Y+VLAPE+ LV+ ITT  + + V  Y ++   KSDL RTDL K+KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  301  GVFTGAYAINPVNGKEVPIWISDYVLASYGTGAVMAVPAHDDRDYAFATKFGLPINPVLE  360
            GV TG+YAINPVNGKE+P+WI+DYVLASYGTGA+MAVPAHD+RD  FA +F L I PVLE
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  361  GGDITKEAFTEDGPHINSEFLNGLNIEDAKKKMVDWLEDHNCGEKKVNYKLRDWDFSRQR  420
            GG++   AFTEDG HINS+FL+GL+   A  KMV+WLE +  G+ +V Y+LRDW FSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  421  YWGEPIPVIHWEDGETTLVPEDQLPLRLPHATDIKPSGTPESPLANLTDWVNVVDKNGRK  480
            YWGEPIP+IHWEDG +T VPE +LPL LP + DI+PSGT ESPLAN+TDW++V   +G K
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  481  GKRETNTMPNWAGSSWYYLRYVDPHNDKELADYDLLKQWLPVDLYIGGAEHAVRHLLYAR  540
            G+RETNTMP+WAGSSWYYLRY+DPHN   LAD +LLKQWLPVD+Y+GGAEHAV HLLYAR
Sbjct  484  GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYAR  543

Query  541  FWHKVLYDLGVVPTKEPFQRLYNQGLIL--------------------------------  568
            FWHKVLYDLGVVPTKEPFQ+L+NQG+IL                                
Sbjct  544  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEE  603

Query  569  --KNHEKMSKSKGNVVNPDDVIDEYGADSLRMYEMFMGPLDASIDWDDNGPASTKKFLDR  626
              +   KMSKS  NVVNPDDV+++YGAD+LR+YEMFMGPLDASI W ++G  +++KFLDR
Sbjct  604  LEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR  663

Query  627  VWRLFVNDLDLKAIPQERIVDKNDGELDKVYAETVKKVTEDFDALHFNTAISQMMVFINA  686
            V RL         I    I + N G LDKVY ETVK VTE+ D + FNTAI+Q+MVF+NA
Sbjct  664  VYRL---------ITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNA  714

Query  687  AQKAKTIPREYAEGFVKLLAPVAPHMMEEIWQIF-GHDESITYAKWPTYDPAKLVESTVE  745
            A+K   +  +YA GFV+L+AP APH+ EE+WQ + + +ESI+Y  WP+YD +KLVE+ VE
Sbjct  715  ANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVE  774

Query  746  IMVQVNGKLRGKFQAAKDADRDDVQKQAMALPHVQKFLEGKD  787
            I+VQ++GK+++K+  AKD  R+++Q  A+A   VQ  + GKD
Sbjct  775  IVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKD  816

277) leuS in NC_015602


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  901 bits (3413),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 523/820 (64%), Positives = 648/820 (80%), Gaps = 45/820 (5%)

Query  2    YNHKVVEKKWQDYWAKHDTFKTGTDPKKKNYYALDMFPFPSGKGLHVGHPEGYTATDIVS  61
            Y+H  +E KWQ +WA ++TFKTGTD+ K ++YALDMFP+PSG GLHVGHPEGYTATDI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  62   RMKRAQGYNVLHPMGWDAFGLPTEQYALKTGMDPAVVTKQNIANFKEQLNKLGFSYDWDR  121
            R KRAQG NVLHPMGWDAFGLP+EQYA+ TG DPA  T +NIANFK Q+N LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  122  EITTSDPNYYKWTQWVFEQMYENGLAYEAEVPVNWSPDLGTVVANEEVI-DGKTERGGYP  180
            E+ T+DPNYYKWTQW+F ++YE+GLAYEAEVPVNW  +LGT +ANEEV+ DG +ERGGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  181  VYRKNMRQWMLKMTAYADRLLEDLDSLDWPEPVKEMQRNWIGRSVGAQVTFKIKGSDKTF  240
            V RK MRQWMLK+TAYA+RLLEDL+ +DWPE++K+MQRNWIG+S GA+VTFK+K++DK F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  DIFTTRPDTLFGCSYTVLAPENKLVQEITTDGHRDEVNAYIKKIESKSDLERTDLNKDKT  300
             +FTTRPDTLFG +Y+VLAPE+ LV+ ITT ++ + V  Y ++   KSDL RTDL K+KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  301  GVFTGAYAINPVNGKEVPIWISDYVLASYGTGAVMAVPAHDDRDYAFATKFGLPINPVLK  360
            GV TG+YAINPVNGKE+P+WI+DYVLASYGTGA+MAVPAHD+RD  FA +F L I PVL 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  361  GGDISKAAFTEDGPHINSEFLDGLNIKDAKKKMVDWLEDHNCGKKKVNYKLRDWDFSRQR  420
            GG++  AAFTEDG HINS+FLDGL+   A  KMV+WLE +  G+ +V Y+LRDW FSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  421  YWGEPIPVIHWEDGTTSLVPEDQLPLRLPHATDIKPSGTPESPLANLTDWVNVVDENGRK  480
            YWGEPIP+IHWEDGT++ VPE +LPL LP + DI+PSGT ESPLAN+TDW++V  E+G K
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  481  GKRETNTMPNWAGSSWYYLRYVDPHNDKELADYDLLKQWLPVDLYIGGAEHAVRHLLYAR  540
            G+RETNTMP+WAGSSWYYLRY+DPHN   LAD +LLKQWLPVD+Y+GGAEHAV HLLYAR
Sbjct  484  GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYAR  543

Query  541  FWHKVLYDLGVVPTKEPFQRLYNQGLIL--------------------------------  568
            FWHKVLYDLGVVPTKEPFQ+L+NQG+IL                                
Sbjct  544  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEE  603

Query  569  --KNHEKMSKSKGNVVNPDDVIDEYGADSLRMYEMFMGPLDASIDWDDNGPASTKKFLDR  626
              +   KMSKS  NVVNPDDV+++YGAD+LR+YEMFMGPLDASI W ++G  +++KFLDR
Sbjct  604  LEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR  663

Query  627  VWRLFVNDLDLKAIPQERIVDKNDGELDKVYAETVKKVTEDFDALHFNTAISQMMVFINA  686
            V RL         I    I + N G LDKVY ETVK VTE+ D + FNTAI+Q+MVF+NA
Sbjct  664  VYRL---------ITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNA  714

Query  687  AQKAKSIPREYAEGFVKLLAPVAPHMMEEIWQVF-GHDESITYAKWPTYDPAKLVESTVE  745
            A+K   +  +YA GFV+L+AP APH+ EE+WQ + + +ESI+Y  WP+YD +KLVE+ VE
Sbjct  715  ANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVE  774

Query  746  IMVQVNGKLRGKFQAPKDADRDAVQKQALAIEHVKKFLAG  785
            I+VQ++GK+++K+  +KD  R+ +Q  ALA E V+  +AG
Sbjct  775  IVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAG  814

278) leuS in NC_007168


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  900 bits (3410),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 547/837 (66%), Positives = 678/837 (82%), Gaps = 42/837 (5%)

Query  3    YNHKEIEKKWQNYWADNKTFKTSDNLGQKKFYALDMFPYPSGAGLHVGHPEGYTATDIVS  62
            Y+H  IE KWQ +WADN TFKT+ + ++ KFYALDMFPYPSGAGLHVGHPEGYTATDI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRMQGYNVLHPMGWDAFGLPAEQYALDTGNDPREFTKQNIQTFKRQIQELGFSYDWDR  122
            R+KR QG NVLHPMGWDAFGLPAEQYA+DTGNDP EFT +NI  FKRQI+ LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVNTTDPEYYKWTQWIFIQLYNKGLAYVDEVAVNWCPALGTVLSNEEVV-DGVSERGGHP  181
            EVNTTDP+YYKWTQWIF +LY+KGLAY  EV+VNW   LGT ++NEEV+ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VYRRPMKQWVLKITEYAdrlledldeldWPESIKDMQRNWIGRSEGARVSFEIENKDASI  241
            V R+PM+QW+LKIT YA+RLLEDL+E+DWPESIKDMQRNWIG+S GA V+F + + D  +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  DVFTTRPDTIYGTTFLVLSPEHSLVNEITSEDKLEAVKKYQEDSSKKSDLERTDLAKDKS  301
             VFTTRPDT++G+T+ VL+PEH+LV+ IT+ D+ EAV  Y+ ++S KSDL RTDLAK+K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAINPLTGKKLPIWIADYVLSSYGTGAVMAVPAHDERDYEFASKFNLPINEVIA  361
            GV TG+YAINP+ GK +P+WIADYVL+SYGTGA+MAVPAHDERD EFA +FNL I  V+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGDIQKEAYTGVGEHINSGELNGLDNETAISKAIELLVAKGAGEKKVNYKLRDWLFSRQR  421
            GG+++  A+T  G HINS+ L+GLD+ +AI+K +E L A G G+ +V Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPVIHWEDGTMTTVpeeelplllpeTDEIKPSGTGESPLANIDEFVNVIDEKTGM  481
            YWGEPIP+IHWEDGT T+VPE ELPL+LP T +I+PSGTGESPLAN+ + ++V  E  G+
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED-GV  482

Query  482  KGRRETNTMPQWAGSCWYYLRYIDPHNSNMLADPEKLKHWLPVDLYIGGVEHAVLHLLYA  541
            KGRRETNTMPQWAGS WYYLRYIDPHN++ LAD E LK+WLPVD+Y+GG EHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKVLYDLGVVPTKEPFQKLFNQGMILG------------------------------  571
            RFWHKVLYDLGVVPTKEPFQKLFNQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---EGNEKMSKSKGNVVNPDDIVDSHGADTLRLYEMFMGPLDAAIAWSENGLDGSRRFLD  628
               ++  KMSKS  NVVNPDD+V+  GADTLR+YEMFMGPLDA+IAWSE+GL+GSR+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RVWRLFINEDGSLSNKIVENNDNGLDKVYNQTVKKVTEDFNTLNFNTAISQLMVFINDCY  688
            RV RL+   +      I E+N  +LDKVYN+TVK VTE+ + ++FNTAI+QLMVF+N   
Sbjct  663  RVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  689  KAETIYQPYAEGFVKMLAPIAPHIGEELWDRL-GNEDTITYQPWPTYDESLLVDSEVEIV  747
            K + ++  YA GFV+++AP+APH+GEELW+ L ++ ++I+Y PWP+YDES LV+++VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  748  VQVNGKVRAKLNIPKDTSKDEMEALALKDENVKLSIEGKDIKKVIAVPQKLVNIVAK  804
            VQ++GKV+AKL ++KD S++E++ +AL +E+V+  I GKDI KVIAVP+KLVNIV K
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

279) leuS in NC_012793


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  898 bits (3400),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 558/838 (67%), Positives = 668/838 (80%), Gaps = 43/838 (5%)

Query  3    FNHREIEKKWQEYWEKNKTFKTVDDDDKPKFYVLDMFPYPSGAGLHVGHPEGYTATDILA  62
            ++H  IE KWQ +W  N TFKT  D  KPKFY LDMFPYPSGAGLHVGHPEGYTATDIL+
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMKRMQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTEKNINTFRRQIKSLGFSYDWDR  122
            R KR QG NVLHPMGWDAFGLPAEQYA+DTGNDPAEFT  NI  F+RQI++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EINTTDPNYYKWTQWIFLKLYEKGLAYMDEVPVNWCPALGTVLANEEVI-DGKSERGGHP  181
            E+NTTDPNYYKWTQWIF KLYEKGLAY  EVPVNW   LGT +ANEEV+ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VIRKPMKQWLLRITAYAdrlledleeldWPESVKEMQRNWIGRSEGAEIRFEVDGHDETF  241
            V+RKPM+QW+L+ITAYA+RLLEDLEE+DWPES+K+MQRNWIG+S GA++ F V + D  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  TVFTTRPDTLFGATYTVLAPEHPLVEKITTPEQKAAVEAYLDAIKSKSDLERTDLAKEKT  301
            TVFTTRPDTLFGATY+VLAPEH+LV+ ITT++Q  AV  Y      KSDL RTDLAKEKT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAIHPVTGEKLPIWIADYVLMSYGTGAIMAVPAHDERDYEFAKKFNLPIKEVVA  361
            GV TG+YAI+PV G  +P+WIADYVL SYGTGAIMAVPAHDERD EFAK+FNL I  V+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGDIAKEAYTGDGEHINSDFLNGLNKEEAIKKMIEWLEANGKGQKKVTYRLRDWLFSRQR  421
            GG++   A+T DG HINSDFL+GL+K  AI KM+EWLEA+G G+ +VTYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPIIHWEDGTMTPVpeeelplklpkTDKIKPTGTGESPLANIEEWVNVVDPKTGK  481
            YWGEPIPIIHWEDGT T+VPE ELPL LP T  I+P+GTGESPLAN+ +W++V     G 
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT-REDGV  482

Query  482  KGRRETNTMPQWAGSCWYYLRYIDPHNDKQLADPEKLKKWLPVDVYIGGAEHAVLHLLYA  541
            KGRRETNTMPQWAGS WYYLRYIDPHN  +LAD E LK+WLPVD+Y+GGAEHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKFLYDIGVVPTKEPFQKLFNQGMILG------------------------------  571
            RFWHK LYD+GVVPTKEPFQKLFNQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---ENNEKMSKSRGNVVNPDDIIESHGADTLRLYEMFMGPLEASIAWSTKGLDGARRFLD  628
               +   KMSKS  NVVNPDD++E  GADTLR+YEMFMGPL+ASIAWS  GL+G+R+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RVWRLFVDENGNLNPKIVDNPETDTLERVYHQTVKKVTEDYEALRFNTAISQLMVFINEA  688
            RV RL       +  K + + ++++L++VY++TVK VTE+ + ++FNTAI+QLMVF+N A
Sbjct  663  RVYRL-------ITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAA  715

Query  689  YKAPVLPKEYMEGFVKLLSPVCPHIGEELWEKL-GHNNTIAYEPWPTYDESKLveeevei  747
             K   L  +Y  GFV+L++P  PH+GEELW+ L +  ++I+Y PWP+YDESKLVE++VEI
Sbjct  716  NKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEI  775

Query  748  vvqvNGKVRAKLRVPADISKEKLEQLAMEDEKIKEHIAGKTVRKVITVPGKLVNIVAN  805
            VVQ++GKV+AKL V+ D+S+E L+++A+ +EK++ +IAGK + KVI+VP KLVNIV +
Sbjct  776  VVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

280) leuS in NC_018673


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  897 bits (3398),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 534/835 (64%), Positives = 676/835 (81%), Gaps = 41/835 (4%)

Query  3    YEHQKIEQKWQKFWSDNHTFKTTDDTSKPKYYALDMFPYPSGQGLHVGHPEGYTATDIMS  62
            Y+H  IE KWQ FW+DNHTFKT  D+SKPK+YALDMFPYPSG GLHVGHPEGYTATDI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RFKRAKGFNVLHPMGWDAFGLPAEQYAMKTGHNPADFTSQNVAHFREQIQSLGLSYDWDR  122
            RFKRA+G NVLHPMGWDAFGLPAEQYAM TG++PA+FT++N+A+F+ QI++LG+SYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EINTTDPEYYKWTQWIFEKLYEKGLAYESKMMVNW-DPIDRVVLANEEVIDGKSERSGNR  181
            E+NTTDP+YYKWTQWIF KLYEKGLAYE+ + VNW + ++  +  +E + DG SER+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERKALRQWVLKITAYADRLVDDLEELDWPEAIKEQQRHWIGRSKGAAVFFNIDHSDKQI  241
            V RK++RQW+LKITAYA+RL++DLEE+DWPE+IK+ QR+WIG+S GA V F++ ++DK++
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  EVYTTRPDTLFGASYMVLAPEHELVNEIMTDEQSQAVSDYRAMISAKSDLERTDLNKDKT  301
             V+TTRPDTLFGA+Y VLAPEH LV+ I T +Q++AV+DY+   S KSDL RTDL K+KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYGINPVNGEKLPIWIADYVLASYGTGAIMAVPAHDERDFEFANKFNLTIKPVIE  361
            GV TG+Y+INPVNG  +P+WIADYVLASYGTGAIMAVPAHDERD EFA++FNL I PV+E
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGDITQAPYIGDGVHINSDFLNGLDKVTAIDNIISWLEEHGAGHSQTNFRLRDWIFSRQR  421
            GG++ +A++  DG+HINSDFL+GLDK +AI +++ WLE +G G+ +  +RLRDW+FSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPVIHWEDGTKSlvpenelplllpRATELRPSGNGESPLANLTDWLEVTREDGVK  481
            YWGEPIP+IHWEDGT + VPE+ELPL+LP + ++RPSG GESPLAN+TDWLEVTREDGVK
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  482  GRRETNTMPQWAGSSWYFLRFVDPHNQEKLADPDKLKYWMNVDLYVGGAEHAVLHLLYAR  541
            GRRETNTMPQWAGSSWY+LR++DPHN EKLAD + LK W+ VD+YVGGAEHAVLHLLYAR
Sbjct  484  GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYAR  543

Query  542  FWHKFLYNLGVVPTKEPFQKLVNQGMILGGN-----------------------------  572
            FWHK LY+LGVVPTKEPFQKL NQGMILG +                             
Sbjct  544  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEE  603

Query  573  ----HEKMSKSKGNVVNPDDIVAQFGADTLRVYEMFMGPLTQSKPWSEEGITGSrrwldr  628
                  KMSKS  NVVNPDD+V Q+GADTLRVYEMFMGPL  S +WSEEG+ GSR+ LDR
Sbjct  604  LEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR  663

Query  629  vwrllvddAGQLRDHVTTVNQGDLDKVYNQTVKKVTDDVENMRFNTAISQMMVFVNEAYK  688
            V RL+         ++T  N G LDKVYN+TVK VT++V++M+FNTAI+Q+MVFVN A K
Sbjct  664  VYRLITT------KEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANK  717

Query  689  SEALPIDYMNGFTQLLAPFAPHMAEELWLRL-GHESSITYVTWPEYDETQIVDDTVEIIF  747
             + L  DY +GF QL+APFAPH++EELW  L +   SI+YV WP YDE+++V++ VEI+ 
Sbjct  718  EDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVV  777

Query  748  QVNGKVRGKAKVTRDIDKNSMIDLAKADENVQNFIDGKEIRKIIAIPGKFINIVV  802
            Q++GKV++K  V++D+ ++ + ++A A+E+VQ  I GK+I K+IA+P K++NIV+
Sbjct  778  QIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

281) M493_14690 in NC_022080


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  896 bits (3393),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 561/838 (67%), Positives = 673/838 (81%), Gaps = 43/838 (5%)

Query  3    FNHRDIEKKWQHYWEQNKTFRTPDDDDKPKFYVLDMFPYPSGAGLHVGHPEGYTATDILA  62
            ++H  IE KWQ +W +N TF+T  D  KPKFY LDMFPYPSGAGLHVGHPEGYTATDIL+
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMKRMQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTQKNIDNFRRQIKSLGFSYDWDR  122
            R KR QG NVLHPMGWDAFGLPAEQYA+DTGNDPAEFT  NI NF+RQI++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EINTTDPNYYKWTQWIFLKLYEKGLAYMDEVPVNWCPALGTVLANEEVI-NGRSERGGHP  181
            E+NTTDPNYYKWTQWIF KLYEKGLAY  EVPVNW   LGT +ANEEV+ +G SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VIRKPMRQWILKITAYAdrlledleeldWPESIKEMQRNWIGRSEGAEIQFAVDGHDETF  241
            V+RKPMRQW+LKITAYA+RLLEDLEE+DWPESIK+MQRNWIG+S GA++ F V + D  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  TVFTTRPDTLFGATYAVLAPEHPLVENITTPEQKPAVEAYLHEVERKSDLERTDLAKEKT  301
            TVFTTRPDTLFGATYAVLAPEH+LV+ ITT++Q  AV  Y ++   KSDL RTDLAKEKT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAIHPVTGERLPIWIADYVLMGYGTGAIMAVPAHDERDYEFAKTFHLPIKEVVA  361
            GV TG+YAI+PV G  +P+WIADYVL +YGTGAIMAVPAHDERD EFAK F+L I  V+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGNVEREPYTGDGEHINSEFLNGLNKQEAIEKMIAWLEEHGKGQKKVSYRLRDWLFSRQR  421
            GGNVE  ++T DG HINS+FL+GL+K  AI KM+ WLE +G G+ +V+YRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPIIHWEDGTMTpvpedelplvlpKTDEIKPSGTGESPLANIEEWVNVVDPNTGK  481
            YWGEPIPIIHWEDGT T+VPE ELPLVLP T +I+PSGTGESPLAN+ +W++V   + G 
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT-REDGV  482

Query  482  KGRRETNTMPQWAGSCWYYLRYIDPHNDKQLADPEKLKKWLPVDVYIGGAEHAVLHLLYA  541
            KGRRETNTMPQWAGS WYYLRYIDPHN  +LAD E LK+WLPVD+Y+GGAEHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKFLYDLGVVPTKEPFQKLFNQGMILG------------------------------  571
            RFWHK LYDLGVVPTKEPFQKLFNQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---ENNEKMSKSKGNVVNPDDIVDSHGADTLRLYEMFMGPLEASIAWSTKGLDGARRFLD  628
               +   KMSKS  NVVNPDD+V+  GADTLR+YEMFMGPL+ASIAWS  GL+G+R+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RVWRLFVTEEGGLNPNIVEEPAADTLERVYHQTVKKVTEDYEALRFNTAISQLMVFINEA  688
            RV RL+ T E       + E  +++L++VY++TVK VTE+ + ++FNTAI+QLMVF+N A
Sbjct  663  RVYRLITTKE-------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAA  715

Query  689  YKAEQMKKEYMEGFVKLLSPVCPHIGEELWQKL-GHTDTIAYEPWPAYDETKLVDDVVEI  747
             K +++  +Y  GFV+L++P  PH+GEELWQ L +  ++I+Y PWP+YDE+KLV++ VEI
Sbjct  716  NKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEI  775

Query  748  VVQINGKVRSRLHVPadlakealeeraladekIKEQLEGKTVRKVIAVPGKLVNIVAN  805
            VVQI+GKV+++L V+ DL++E L+E ALA+EK++ ++ GK + KVIAVP KLVNIV +
Sbjct  776  VVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

282) leuS in NC_004461


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  896 bits (3392),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 546/837 (66%), Positives = 680/837 (82%), Gaps = 42/837 (5%)

Query  13   YNHKEIEKKWQNYWEENKTFKTNDNLGQKKFYALDMFPYPSGAGLHVGHPEGYTATDIIS  72
            Y+H  IE KWQ +W +N TFKT  + ++ KFYALDMFPYPSGAGLHVGHPEGYTATDI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  73   RYKRMQGYNVLHPMGWDAFGLPAEQYALDTGNDPREFTQKNIQTFKRQIQELGFSYDWDR  132
            R+KR QG NVLHPMGWDAFGLPAEQYA+DTGNDP EFT  NI  FKRQI+ LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  133  EVNTTDPEYYKWTQWIFIQLYNKGLAYVDEVAVNWCPALGTVLSNEEVV-DGVSERGGHP  191
            EVNTTDP+YYKWTQWIF +LY+KGLAY  EV+VNW   LGT ++NEEV+ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  192  VYRKPMKQWVLKITEYAdrlledldeldWPESIKDMQRNWIGRSEGAKVTFKIEQSDQNI  251
            V RKPM+QW+LKIT YA+RLLEDL+E+DWPESIKDMQRNWIG+S GA+VTFK+ ++D+++
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  252  EVFTTRPDTIYGTSFLVLSPEHPLVNEITTSDKEQEVKLYQNEASKKSDLERTDLAKEKT  311
             VFTTRPDT++G+++ VL+PEH+LV+ ITTSD+ + V  Y+ +AS KSDL RTDLAKEKT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  312  GVFTGTFAINPLSGDKLPIWIADYVLSTYGTGAVMAVPGHDERDHEFATKFNLPIIEVIE  371
            GV TG++AINP++G  +P+WIADYVL++YGTGA+MAVP+HDERD EFA +FNL II V+E
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  372  GGEVQKYAYTGEGKHINSGELDGLENEAAISKAIELLESKGAGEKKVNYKLRDWLFSRQR  431
            GG+V+  A+T +G HINS+ LDGL++ +AI+K +E LE+ G G+ +V Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  432  YWGEPIPIIHWEDGSMttvpedelplllpetdeIKPSGTGESPLANIDAFVNVIDEKTGM  491
            YWGEPIPIIHWEDG+ T+VPE ELPL+LP T +I+PSGTGESPLAN+   ++V  E  G+
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED-GV  482

Query  492  KGRRETNTMPQWAGSCWYYLRYIDPHNEKMIADPEKLKHWLPVDLYIGGVEHAVLHLLYA  551
            KGRRETNTMPQWAGS WYYLRYIDPHN   +AD E LK+WLPVD+Y+GG EHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  552  RFWHKVLYDLGVVPTKEPFQKLYNQGMILG------------------------------  581
            RFWHKVLYDLGVVPTKEPFQKL+NQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  582  ---EGNEKMSKSKGNVINPDDIVASHGADTLRLYEMFMGPLDAAIAWSEKGLDGSRRFLD  638
               ++  KMSKS  NV+NPDD+V   GADTLR+YEMFMGPLDA+IAWSE GL+GSR+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  639  RVWRLIITDENSINKKIVDSNNHSLDKVYNQTVKKVTEDFDTLSFNTAISQLMVFINECY  698
            RV RLI T      K I + N+ +LDKVYN+TVK VTE+ D + FNTAI+QLMVF+N   
Sbjct  663  RVYRLITT------KEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  699  KTNEVYKPYIEGFVKMLSPIAPHIGEELWDRL-GHENTITYQPWPTFDESLLVDDEVEIV  757
            K + ++  Y  GFV++++P+APH+GEELW+ L +  ++I+Y PWP++DES LV+++VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  758  VQVNGKVRAKINIPKDLSKEEMQDLALSNDNVKMSIEGKEVKKVIAVPQKLVNIVAK  814
            VQ++GKV+AK+ ++KDLS+EE+Q++AL+N++V+  I GK++ KVIAVP+KLVNIV K
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

283) leuS in NC_002976


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  896 bits (3393),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 546/837 (66%), Positives = 680/837 (82%), Gaps = 42/837 (5%)

Query  3    YNHKEIEKKWQNYWEENKTFKTNDNLGQKKFYALDMFPYPSGAGLHVGHPEGYTATDIIS  62
            Y+H  IE KWQ +W +N TFKT  + ++ KFYALDMFPYPSGAGLHVGHPEGYTATDI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRMQGYNVLHPMGWDAFGLPAEQYALDTGNDPREFTQKNIQTFKRQIQELGFSYDWDR  122
            R+KR QG NVLHPMGWDAFGLPAEQYA+DTGNDP EFT  NI  FKRQI+ LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVNTTDPEYYKWTQWIFIQLYNKGLAYVDEVAVNWCPALGTVLSNEEVV-DGVSERGGHP  181
            EVNTTDP+YYKWTQWIF +LY+KGLAY  EV+VNW   LGT ++NEEV+ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VYRKPMKQWVLKITEYAdrlledldeldWPESIKDMQRNWIGRSEGAKVTFKIEQSDQNI  241
            V RKPM+QW+LKIT YA+RLLEDL+E+DWPESIKDMQRNWIG+S GA+VTFK+ ++D+++
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  EVFTTRPDTIYGTSFLVLSPEHPLVNEITTSDKEQEVKLYQNEASKKSDLERTDLAKEKT  301
             VFTTRPDT++G+++ VL+PEH+LV+ ITTSD+ + V  Y+ +AS KSDL RTDLAKEKT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGTFAINPLSGDKLPIWIADYVLSTYGTGAVMAVPGHDERDHEFATKFNLPIIEVIE  361
            GV TG++AINP++G  +P+WIADYVL++YGTGA+MAVP+HDERD EFA +FNL II V+E
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGEVQKYAYTGEGKHINSGELDGLENEAAISKAIELLESKGAGEKKVNYKLRDWLFSRQR  421
            GG+V+  A+T +G HINS+ LDGL++ +AI+K +E LE+ G G+ +V Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPIIHWEDGSMttvpedelplllpetdeIKPSGTGESPLANIDAFVNVIDEKTGM  481
            YWGEPIPIIHWEDG+ T+VPE ELPL+LP T +I+PSGTGESPLAN+   ++V  E  G+
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED-GV  482

Query  482  KGRRETNTMPQWAGSCWYYLRYIDPHNEKMIADPEKLKHWLPVDLYIGGVEHAVLHLLYA  541
            KGRRETNTMPQWAGS WYYLRYIDPHN   +AD E LK+WLPVD+Y+GG EHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKVLYDLGVVPTKEPFQKLYNQGMILG------------------------------  571
            RFWHKVLYDLGVVPTKEPFQKL+NQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---EGNEKMSKSKGNVINPDDIVASHGADTLRLYEMFMGPLDAAIAWSEKGLDGSRRFLD  628
               ++  KMSKS  NV+NPDD+V   GADTLR+YEMFMGPLDA+IAWSE GL+GSR+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RVWRLIITDENSINKKIVDSNNHSLDKVYNQTVKKVTEDFDTLSFNTAISQLMVFINECY  688
            RV RLI T      K I + N+ +LDKVYN+TVK VTE+ D + FNTAI+QLMVF+N   
Sbjct  663  RVYRLITT------KEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  689  KTNEVYKPYIEGFVKMLSPIAPHIGEELWDRL-GHENTITYQPWPTFDESLLVDDEVEIV  747
            K + ++  Y  GFV++++P+APH+GEELW+ L +  ++I+Y PWP++DES LV+++VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  748  VQVNGKVRAKINIPKDLSKEEMQDLALSNDNVKMSIEGKEVKKVIAVPQKLVNIVAK  804
            VQ++GKV+AK+ ++KDLS+EE+Q++AL+N++V+  I GK++ KVIAVP+KLVNIV K
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

284) leuS in NC_020164


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  896 bits (3395),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 548/837 (66%), Positives = 675/837 (81%), Gaps = 42/837 (5%)

Query  3    YNHNEIEKKWQKYWEDNKTFKTQDNLGQKKFYALDMFPYPSGAGLHVGHPEGYTATDIIS  62
            Y+H  IE KWQ +W DN TFKT  + ++ KFYALDMFPYPSGAGLHVGHPEGYTATDI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRMQGYNVLHPMGWDAFGLPAEQYALDTGNDPREFTQKNIQTFKRQIQELGFSYDWDR  122
            R+KR QG NVLHPMGWDAFGLPAEQYA+DTGNDP EFT  NI  FKRQI+ LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVNTTDPNYYKWTQWIFIQLYNKGLAYVDEVAVNWCPTLGTVLSNEEVV-DGVSERGGHP  181
            EVNTTDPNYYKWTQWIF +LY+KGLAY  EV+VNW   LGT ++NEEV+ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VYRKPMKQWVLKITEYAdrlledledldWPESIKDMQRNWIGRSEGARVSFNVKDTDEKV  241
            V RKPM+QW+LKIT YA+RLLEDLE++DWPESIKDMQRNWIG+S GA V+F+VKDTD   
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  EVFTTRPDTIFGTSFLVLSPEHTLVNQITSDDKLEEVKAYQTEASKKSDLERTDLAKGKT  301
             VFTTRPDT+FG+++ VL+PEH+LV+ IT+ D+ E V  Y+ +AS KSDL RTDLAK KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAINPVSGEQLPIWIADYVLSTYGTGAVMAVPGHDERDHEFAEKFELPIIEVIE  361
            GV TG+YAINPV+G ++P+WIADYVL++YGTGA+MAVP+HDERD EFA +F+L II V+E
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGDVQTEAYTGNGPHVNSGELNGLYNDEAISKAIELLEANQAGEKKVNYKLRDWLFSRQR  421
            GG+V+  A+T +G H+NS+ L+GL +  AI+K +E LEA+  G+ +V Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPIIHWEDGSMSTVleselplllpeTDEIKPSGTGESPLANIDDFVNVTDEKTGM  481
            YWGEPIPIIHWEDG+ ++V ESELPL+LP T +I+PSGTGESPLAN+ D ++VT E  G+
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED-GV  482

Query  482  KGRRETNTMPQWAGSCWYYLRYIDPDNDKMIADPEKLKHWLPVDLYIGGVEHAVLHLLYA  541
            KGRRETNTMPQWAGS WYYLRYIDP+N   +AD E LK+WLPVD+Y+GG EHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKVLYDLGVVPTKEPFQKLYNQGMILG------------------------------  571
            RFWHKVLYDLGVVPTKEPFQKL+NQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---EGNEKMSKSKGNVINPDDIVNSHGADTLRLYEMFMGPLDAAIAWSDKGLDGSRRFLD  628
               ++  KMSKS  NV+NPDD+V+  GADTLR+YEMFMGPLDA+IAWS+ GL+GSR+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RVWRLIVKEDGSLSDKIVETNNKSLDKTYNQTVKKVTEDFDTLGFNTAISQLMVFINDCY  688
            RV RLI   +      I E N+ +LDK YN+TVK VTE+ D + FNTAI+QLMVF+N   
Sbjct  663  RVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  689  KADEIYKPYIEGFVTMLAPIAPHIGEELWDRL-GHSDTITYQPWPTYNESLLVDDEVEIV  747
            K D ++  Y  GFV ++AP+APH+GEELW+ L + +++I+Y PWP+Y+ES LV+++VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  748  VQVNGKLRAKIEIPKDLSKEEMQDLALANDNVKMSIEGKEIKKVIAVPQKLVNIVAK  804
            VQ++GK++AK+ ++KDLS+EE+Q++ALAN++V+  I GK+I KVIAVP+KLVNIV K
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

285) leuS in NC_013791


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  895 bits (3390),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 559/839 (67%), Positives = 669/839 (80%), Gaps = 45/839 (5%)

Query  3    FSHLDIEKKWQKHWEENKTFKTTEEADKPKFYALDMFPFPSGAGLHVGHPEGYTATDILS  62
            + H  IE KWQ  W +N TFKT  +A KPKFYALDMFP+PSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMKRMQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTLKNIDTFRRQIKSLGFSYDWDR  122
            R KR QG NVLHPMGWDAFGLPAEQYA+DTGNDPAEFT  NI  F+RQI++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVNTIDPDYYKWTQWIFLKLYEKGLAYIDEVAVNWCPALGTVLANEEVI-DGKSERGGHP  181
            EVNT DP+YYKWTQWIF KLYEKGLAY  EV+VNW   LGT +ANEEV+ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRPMKQWMLKITAYAdrlledldeldWSESIKDMQRNWIGRSEGAEVTFKVDGHDAEK  241
            V R+PM+QWMLKITAYA+RLLEDL+E+DW+ESIKDMQRNWIG+S GA+VTFKV + D + 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKD-  242

Query  242  VDVFTTRPDTLFGATYMVLAPEHKLVDVITTAEQQEAVEKYKKQVALKSDLERTELSKEK  301
              VFTTRPDTLFGATY VLAPEH LVD ITT++Q EAV  YK+Q +LKSDL RT+L+KEK
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEK  302

Query  302  TGVFTGAFAVNPANGKRIPIWIADYVLVSYGTGAIMAVPAHDERDYEFAKTFDLEIIEVV  361
            TGV TG++A+NP NGK +P+WIADYVL SYGTGAIMAVPAHDERD EFAK F+L+II V+
Sbjct  303  TGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL  362

Query  362  AGGDVLKEAYTGDGEHVNSDFLNGLDKESAITNMIEWLEANHYGTKKVTYRLRDWLFSRQ  421
             GG+V   A+T DG H+NSDFL+GLDK SAI++M+EWLEA+  G  +VTYRLRDWLFSRQ
Sbjct  363  EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQ  422

Query  422  RYWGEPIPMIHWEDGSMTPVAYEELPLTLPKMDEIKPSDTGESPLANHKEWLEVTDPKTG  481
            RYWGEPIP+IHWEDG+ T+V+  ELPL LP   +I+PS+TGESPLAN  +WLEVT    G
Sbjct  423  RYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT-REDG  481

Query  482  MKGRRETNTMPNWAGSCWYYLRYIDPNNSEALADPEKLKQWLPVDIYIGGAEHAVLHLLY  541
            +KGRRETNTMP+WAGS WYYLRYIDP+N+E LAD E LKQWLPVDIY+GGAEHAVLHLLY
Sbjct  482  VKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLY  541

Query  542  ARFWHKFLYDLGVVPTKEPFQKLYNQGMILG-----------------------------  572
            ARFWHK LYDLGVVPTKEPFQKL+NQGMILG                             
Sbjct  542  ARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETG  601

Query  573  ----ENNEKMSKSKGNVVNPDDIVLSHGADTLRLYEMFMGPLDASIAWSTNGLDGARRFL  628
                +   KMSKS  NVVNPDD+V   GADTLR+YEMFMGPLDASIAWS +GL+G+R+FL
Sbjct  602  EELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFL  661

Query  629  DRVWRLFIDEKTNELNPAITDTKGTDEFIRTYHQTVKKVTEDFAALRFNVGISQMMVFIN  688
            DRV RL+      E N++  D        + Y++TVK VTE+   ++FN +I+Q+MVF+N
Sbjct  662  DRVYRLITTKEITEENSGALD--------KVYNETVKAVTEQVDQMKFNTAIAQLMVFVN  713

Query  689  DAYKQEKLPRELMEGFVKLLAPLAPHIAEELWQKF-GHNETITYAEWPTYeesllvenev  747
             A K++KL  +   GFV+L+AP+APH++EELWQ + +  E+I+Y  WP+Y+ES LVEN+V
Sbjct  714  AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDV  773

Query  748  evvvQINGKVRAKLVIPADASRDQMEEIAKNDDKVQEAIGGKTVRKIIAVPGKLVNIVV  806
            E+VVQI+GKV+AKLV++ D SR++++E+A  ++KVQ  I+GK + K+IAVP KLVNIV+
Sbjct  774  EIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

286) leuS in NC_016805


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  894 bits (3386),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 539/840 (65%), Positives = 673/840 (81%), Gaps = 46/840 (5%)

Query  3    YDHKSIEAKWQKYWDEHETFRAPDKSEKEKYYVMDMFPYPSGQGLHVGHPEGYTATDIMS  62
            YDH +IE+KWQ +W +++TF++   + K K+Y +DMFPYPSG GLHVGHPEGYTATDI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRAKGFNVLHPMGWDAFGLPAEQYAIKTGNNPAGFTNKNVQVFKNQIKSLGFSIDWSR  122
            R+KRA+G NVLHPMGWDAFGLPAEQYA+ TGN+PA FT  N+  FK QI++LGFS DW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EINTTDPEYYKWSQWIFEKLYEKGLAYEDEIMVNWAPDFPGGGIVVANEEVI-DGKTERG  181
            E+NTTDP+YYKW+QWIF KLYEKGLAYE E+ VNW  ++   G  +ANEEV+ DG +ERG
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEEL---GTAIANEEVLPDGTSERG  180

Query  182  GYPVYRKPMKQWVLRITAYAdrlledledldWPEAIKEQQRHWIGKSIGASVFFNIADSD  241
            GYPV RKPM+QW+L+ITAYA+RLLEDLE++DWPE+IK+ QR+WIGKS GA+V F++ D+D
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  242  KQIEVYTTRPDTLFGAQYMVLSPEHELVDEITTLEQKEAIANYKKEVETKSDLERTDLNK  301
            K++ V+TTRPDTLFGA Y VL+PEH LVD ITT +Q EA+A+YK++   KSDL RTDL K
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  302  DKTGAFTGAYATNPINGEKLPIWIADYVLSSYGTGAIMAVPAHDDRDWEFAKKFNLPIKA  361
            +KTG  TG+YA NP+NG  +P+WIADYVL+SYGTGAIMAVPAHD+RDWEFAK+FNL I +
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  362  VIEGGDVEEAAYTDDGTHINSGFLDGLNKQEAIDKAISWLEEHNAGHQQINYRLRDWIFS  421
            V+EGG+VEEAA+T+DG HINS+FLDGL+K  AI K + WLE +  G++++ YRLRDW+FS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  422  RQRYWGEPIPVIHWEDGTQTLVPESELPLRLPEMTQEQLKPSGTGESPLANATDWLNVTR  481
            RQRYWGEPIP+IHWEDGT T VPESELPL LP     +++PSGTGESPLAN TDWL+VTR
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLP--VTKDIRPSGTGESPLANVTDWLEVTR  478

Query  482  EDGVKGRRETNTMPQWAGSSWYFLRYVDPHNSEALADPEKLKYWMNVDLYVGGAEHAVLH  541
            EDGVKGRRETNTMPQWAGSSWY+LRY+DPHN+E LAD E LK W+ VD+YVGGAEHAVLH
Sbjct  479  EDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLH  538

Query  542  LLYARFWHKFLYDLGVVPTKEPFQKLVNQGMILG--------------------------  575
            LLYARFWHK LYDLGVVPTKEPFQKL NQGMILG                          
Sbjct  539  LLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHV  598

Query  576  -------ENHEKMSKSKGNVVNPDEIVNNYGADTLRVYEMFMGPLTQSKPWSEDGVAGSr  628
                   +   KMSKS  NVVNPD++V++YGADTLRVYEMFMGPL  S +WSE+G+ GSR
Sbjct  599  ETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSR  658

Query  629  rwldrvwrllvdEEDKLRDHVTTVNKGDLDKIYHQTVKKVSEDLENMRFNTAISQLMVFV  688
            + LDRV RL+   E      +T  N G LDK+Y++TVK V+E++++M+FNTAI+QLMVFV
Sbjct  659  KFLDRVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFV  712

Query  689  NEAYKSEALPVQYMDGFVQMLAPIAPHLAEELWSKL-GHEEDISYVSWPTYDESQLVEDS  747
            N A K + L  +Y  GFVQ++AP+APHL+EELW  L +  E ISYV+WP+YDES+LVE+ 
Sbjct  713  NAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVEND  772

Query  748  VEIIFQVNGKVRGKATVARNIDKDAMLDYAKADENVQNFISGKEIRKIIAIPGKFVNIVV  807
            VEI+ Q++GKV++K  VA+++ ++ + + A A+E+VQ  I+GK+I K+IA+P K+VNIV+
Sbjct  773  VEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

287) leuS in NC_016605


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  894 bits (3385),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 520/821 (64%), Positives = 659/821 (81%), Gaps = 43/821 (5%)

Query  3    FNHHEIEPKWQKYWSDHETFKTNATEDKPKYYALDMFPYPSGQGLHVGHPEGYTATDIMS  62
            ++H  IEPKWQ +W+D++TFKT +   KPK+YALDMFPYPSG GLHVGHPEGYTATDI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMKRMQGFKVLHPMGWDAFGLPAEQYAMKTGHNPKDFTKDNIKNFKRQIQSLGFSYDWSR  122
            R KR QG +VLHPMGWDAFGLPAEQYAM TG++P +FT +NI NFKRQI++LGFSYDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EINTTDPSYYKWTQWIFEQMYKKGLAYEKETLVNWAPDLMGGTVVANEEVI-NGRTERGD  181
            E+NTTDP+YYKWTQWIF ++Y KGLAYE E  VNW  +L  GT +ANEEV+ +G +ERG+
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEEL--GTAIANEEVLPDGTSERGG  181

Query  182  FPVFRVPMKQWILKITAYAdrllddldlvdWPESIKEMQRNWIGRSVGASVNFKVEDTEE  241
            +PV R PM+QW+LKITAYA+RLL+DL+ VDWPESIK+MQRNWIG+S GA+V FKV DT+ 
Sbjct  182  YPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDK  241

Query  242  NIEVFTTRADTLFGVTYLVVSPEHDIVERITTAENKAKVTEYQKQVATKSDLERTDLNKD  301
            ++ VFTTR+DTLFG TY V++PEH +V+ ITT+++   V++Y++Q + KSDL RTDL K+
Sbjct  242  DFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKE  301

Query  302  KTGVFTGAYAINPVNGKKVPIWIADYVLSSYGTGAVMAVPAHDPRDFEFAKKFGIEIIPV  361
            KTGV TG+YAINPVNGK +P+WIADYVL+SYGTGA+MAVPAHD RD EFAK+F ++IIPV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  362  IEGGNIEDGAYEGDGTHINSAFLNGLDKQAALSSMLTWIKENGVGDKKVNYRLRDWVFSR  421
            +EGGN+E++A+  DG HINS FL+GLDK +A++ M+ W+  +GVG+ +V YRLRDW+FSR
Sbjct  362  LEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSR  421

Query  422  QRYWGEPIPIIHWEDGETGLVPENELPLRLPATDDLKPSGTGESPLANLDDWLNVVDENG  481
            QRYWGEPIPIIHWEDG +  VPE+ELPL LP T D++PSGTGESPLAN+ DWL+V  E+G
Sbjct  422  QRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDG  481

Query  482  RKGRRETNTMPQWAGSSWYYLRYIDPKNDQEIADKQLLKEWMPVDLYVGGAEHAVLHLLY  541
             KGRRETNTMPQWAGSSWYYLRYIDP N + +AD +LLK+W+PVD+YVGGAEHAVLHLLY
Sbjct  482  VKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLY  541

Query  542  ARFWHKVLYDLGVVPTKEPFQKLVNQGMILGSN---------------------------  574
            ARFWHKVLYDLGVVPTKEPFQKL NQGMILG++                           
Sbjct  542  ARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETG  601

Query  575  ------HEKMSKSKGNVVNPDDIVDKYGADTLRIYEMFMGPLTESVSWSEDGLNGSRKWL  628
                    KMSKS  NVVNPDD+V++YGADTLR+YEMFMGPL  S++WSE+GL+GSRK L
Sbjct  602  EELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFL  661

Query  629  DRVWRLFIDDDGKLRDRITKVNDGKLDLIFNKTVQKVSNDFENMRFNTGISQLMVFINEA  688
            DRV RL+   +      IT  N G LD ++N TV+ V+++ ++M+FNT+I+QLMVF+N A
Sbjct  662  DRVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAA  715

Query  689  YKVDSIYVKYVEDFVKILSPLAPHLAEELWSRL-GYKETISYEKWPTVDESKLVEDTVEV  747
             K D ++  Y  +FV++++P+APHL+EELW  L +  E+ISY  WP+ DESKLVE+ VE+
Sbjct  716  NKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEI  775

Query  748  ILQINGKVRGRLTVEKDLKQEQLQKLAMDSDSVQQWINGKE  788
            ++QI+GKV+++L V KDL +E+LQ +A+ ++ VQ  I GK+
Sbjct  776  VVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKD  816

288) leuS in NC_008531


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  893 bits (3383),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 539/840 (65%), Positives = 672/840 (80%), Gaps = 46/840 (5%)

Query  3    YDHKSIEAKWQKYWDEHETFRAPDKSEKEKYYVMDMFPYPSGQGLHVGHPEGYTATDIMS  62
            YDH +IE+KWQ +W +++TF++   + K K+Y +DMFPYPSG GLHVGHPEGYTATDI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRAKGFNVLHPMGWDAFGLPAEQYAIKTGNNPAGFTNKNVQVFKNQIKSLGFSIDWSR  122
            R+KRA+G NVLHPMGWDAFGLPAEQYA+ TGN+PA FT  N+  FK QI++LGFS DW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EINTTDPEYYKWSQWIFEKLYEKGLAYEDEIMVNWAPDFPGGGIVVANEEVI-DGKTERG  181
            E+NTTDP+YYKW+QWIF KLYEKGLAYE E+ VNW  ++   G  +ANEEV+ DG +ERG
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEEL---GTAIANEEVLPDGTSERG  180

Query  182  GYPVYRKPMKQWVLRITAYAdrlledledldWPEAIKEQQRHWIGKSIGASVFFNIADSD  241
            GYPV RKPM+QW+L+ITAYA+RLLEDLE++DWPE+IK+ QR+WIGKS GA+V F++ D+D
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  242  KQIEVYTTRPDTLFGAQYMVLSPEHELVDEITTLEQKEAIANYKKEVETKSDLERTDLNK  301
            K++ V+TTRPDTLFGA Y VL+PEH LVD ITT +Q EA+A+YK++   KSDL RTDL K
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  302  DKTGAFTGAYATNPINGEKLPIWIADYVLSSYGTGAIMAVPAHDDRDWEFAKKFNLPIKA  361
            +KTG  TG+YA NP+NG  +P+WIADYVL+SYGTGAIMAVPAHD+RDWEFAK+FNL I +
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  362  VIEGGNVEEAAYTDDGTHINSGFLDGLNKQEAIDKAISWLEEHNAGHQQINYRLRDWIFS  421
            V+EGGNVEEAA+T+DG HINS+FLDGL+K  AI K + WLE +  G++++ YRLRDW+FS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  422  RQRYWGEPIPVIHWEDGTQTLVPESELPLRLPEMTQEQLKPSGTGESPLANATDWLNVTR  481
            RQRYWGEPIP+IHWEDGT T VPESELPL LP     +++PSGTGESPLAN TDWL+VTR
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLP--VTKDIRPSGTGESPLANVTDWLEVTR  478

Query  482  KDGVKGRRETNTMPQWAGSSWYFLRYVDPHNSEALADPEKLKYWMNVDLYVGGAEHAVLH  541
             DGVKGRRETNTMPQWAGSSWY+LRY+DPHN+E LAD E LK W+ VD+YVGGAEHAVLH
Sbjct  479  EDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLH  538

Query  542  LLYARFWHKFLYDLGVVPTKEPFQKLVNQGMILG--------------------------  575
            LLYARFWHK LYDLGVVPTKEPFQKL NQGMILG                          
Sbjct  539  LLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHV  598

Query  576  -------ENHEKMSKSKGNVVNPDEIVNNYGADTLRVYEMFMGPLTQSKPWSEDGVSGSr  628
                   +   KMSKS  NVVNPD++V++YGADTLRVYEMFMGPL  S +WSE+G+ GSR
Sbjct  599  ETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSR  658

Query  629  rwldrvwrllvdEEDKLRDHVTTVNKGDLDKIYHQTVKKVSEDLENMRFNTAISQLMVFV  688
            + LDRV RL+   E      +T  N G LDK+Y++TVK V+E++++M+FNTAI+QLMVFV
Sbjct  659  KFLDRVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFV  712

Query  689  NEAYKSEALPVQYMDGFVQMLAPIAPHLAEELWSKL-GHEEDISYVSWPTYDESQLVEDS  747
            N A K + L  +Y  GFVQ++AP+APHL+EELW  L +  E ISYV+WP+YDES+LVE+ 
Sbjct  713  NAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVEND  772

Query  748  VEIIFQVNGKVRGKATVARNIDKDAMLDYAKADENVQNFISGKEIRKIIAIPGKFVNIVV  807
            VEI+ Q++GKV++K  VA+++ ++ + + A A+E+VQ  I+GK+I K+IA+P K+VNIV+
Sbjct  773  VEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

289) leuS in NC_010471


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  893 bits (3384),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 533/835 (64%), Positives = 678/835 (82%), Gaps = 41/835 (4%)

Query  3    YEHQQIEQKWQKFWDDNQTFATSDTTDKPKYYAVDMFPYPSGQGLHVGHPEGYTATDIMS  62
            Y+H  IE KWQ FW DN+TF T+  + KPK+YA+DMFPYPSG GLHVGHPEGYTATDI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RFKRAKGFNVLHPMGWDAFGLPAEQYAMKTGHNPADFTSQNIDHFREQIKSLGLSYDWNR  122
            RFKRA+G NVLHPMGWDAFGLPAEQYAM TG++PA+FT++NI +F+ QI++LG+SYDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EINTTDPSYYKWTQWIFEKLYEKGLAYESNMMVNW-DPIDRVVLANEEVIDGKSERSGNK  181
            E+NTTDP+YYKWTQWIF KLYEKGLAYE+++ VNW + ++  +  +E + DG SER+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERKALRQWVLKITAYAdrlvddlddldWPEAIKEQQRNWIGRSKGAAVFFNVDHADAKI  241
            V RK++RQW+LKITAYA+RL++DL+++DWPE+IK+ QRNWIG+S GA V F+V ++D  +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  EVYTTRPDTLFGATYMVLAPEHELVDSIVTAEQKQAVADYRAAIAAKSDLERTDLNKDKT  301
             V+TTRPDTLFGATY VLAPEH LVD+I T++Q +AVADY+   + KSDL RTDL K+KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYGINPINGEKLPIWIADYVLASYGTGAIMAVPAHDDRDFEFAKKFDLAIKPVIA  361
            GV TG+Y+INP+NG  +P+WIADYVLASYGTGAIMAVPAHD+RD EFAK+F+L I PV+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGENDDVAYTGDGVHINSDFLDGLDKATAIDQAIDWLEAHQAGHAQTNFRLRDWIFSRQR  421
            GG+ ++ A+T DG+HINSDFLDGLDKA+AI + ++WLEA+  G+ +  +RLRDW+FSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPVIHWEDGTTSlvpenelplllpHATELRPSGSGESPLANLTDWLEVTRDDGVK  481
            YWGEPIP+IHWEDGT++ VPE+ELPL+LP + ++RPSG+GESPLAN+TDWLEVTR+DGVK
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  482  GRRETNTMPQWAGSSWYFLRYIDPHNDHQLADPEKLKYWMNVDLYVGGAEHAVLHLLYAR  541
            GRRETNTMPQWAGSSWY+LRYIDPHN ++LAD E LK W+ VD+YVGGAEHAVLHLLYAR
Sbjct  484  GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYAR  543

Query  542  FWHKFLYDLGVVPTKEPFQKLVNQGMILGAN-----------------------------  572
            FWHK LYDLGVVPTKEPFQKL NQGMILG++                             
Sbjct  544  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEE  603

Query  573  ----HEKMSKSKGNVVNPDDIVREYGADTLRVYEMFMGPLTQSKPWSEEGITGSRRWLDR  628
                  KMSKS  NVVNPDD+V +YGADTLRVYEMFMGPL  S +WSEEG+ GSR+ LDR
Sbjct  604  LEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR  663

Query  629  VWRLLIDDEGQLRDHVTTVNPGDLDKIYHQTVKKVTDDLENMRFNTAISQMMVFVNDAYK  688
            V RL+   E      +T  N+G LDK+Y++TVK VT+++++M+FNTAI+Q+MVFVN A K
Sbjct  664  VYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANK  717

Query  689  SDALPVTYMNGFIQLLAPFAPHLAEELWVRLGNR-ESISYVSWPTYDDTKLVDDTVEIIF  747
             D L   Y +GF+QL+APFAPHL+EELW  L    ESISYV+WP+YD++KLV++ VEI+ 
Sbjct  718  EDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVV  777

Query  748  QVNGKVRGKATVARDINQDDMITAAKADDNVQNFITGKTVRKVIAIPGKFVNIVV  802
            Q++GKV++K  VA+D++++++   A A+++VQ  I+GK + KVIA+P K+VNIV+
Sbjct  778  QIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

290) leuS in NC_016641


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  892 bits (3378),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 530/836 (64%), Positives = 661/836 (80%), Gaps = 43/836 (5%)

Query  10   YQPQSIEPKWQKYWDENKTFRTGEEPGKPKFYALDMFPYPSGAGLHVGHPEGYTATDIVS  69
            Y+  +IEPKWQ +W +N TF+TG +++KPKFYALDMFPYPSGAGLHVGHPEGYTATDI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  70   RYKRMRGYNVLHPMGWDAFGLPAEQHALDTGEHPREITVKNVNNFRRQIKSLGFSYDWDR  129
            R+KR +G NVLHPMGWDAFGLPAEQ A+DTG++P E+T  N+ NF+RQI++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  130  EISTTDPDYYKWTQWIFIQLYKRGLAYVAEVPVNWCPALGTVLANEEVI-DGKSERGGHP  188
            E++TTDP+YYKWTQWIF +LY +GLAY AEVPVNW   LGT +ANEEV+ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  189  VIRKPMRQWMLKITEYAdrllddleeldWSESIKDMQRNWIGKSTGAEVHFPIEGHDKQL  248
            V+RKPMRQWMLKIT YA+RLL+DLEE+DW+ESIKDMQRNWIGKSTGA+V F + + DK++
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  249  TVFTTRPDTLFGASYCVLAPEQELVDVITTPEQKDVVNQYREQAARKSDLERTDLAKDKT  308
            TVFTTRPDTLFGA+Y VLAPE+ LVD ITT++Q + V +Y+ QA+ KSDL RTDLAK+KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  309  GVFTGAYAVNPVNGEKLPIWIADYVLAGYGTGAIMAVPGHDTRDWEFAKQFGLNIIEVVQ  368
            GV TG+YA+NPVNG  +P+WIADYVLA+YGTGAIMAVP+HD RDWEFAKQF L+II V++
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  369  GGDVAKEPYTEDGPHVNSGPLNGLTNEEAIPKMIEWLEAEGKGQGKVTYRLRDWLFSRQR  428
            GG+V   ++TEDG H+NS+ L+GL +  AI+KM+EWLEAEG G+ +VTYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  429  YWGEPIPVIHLEDGTIKTVPEDQLPLVLPEMDNIKPSGTGESPLANATDWVETVDPETGL  488
            YWGEPIP+IH EDGT  +VPE +LPLVLP   +I+PSGTGESPLAN TDW+E V  E G+
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE-VTREDGV  482

Query  489  KARRETNTMPQWAGSCWYYLRYIDPHNDKEPVSKEKQREWLPVDLYIGGAEHAVLHLLYA  548
            K+RRETNTMPQWAGS WYYLRYIDPHN       E  ++WLPVD+Y+GGAEHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  549  RFWHKVLYDIGVVETKEPFYKLVNQGMILGNN----------------------------  580
            RFWHKVLYD+GVV TKEPF KL NQGMILG +                            
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  581  -----NEKMSKSRGNVINPDDIVNTFGADTLRIYEMFMGPLEATKPWSENGVEGAHRFLS  635
                   KMSKS  NV+NPDD+V+ +GADTLR+YEMFMGPL+A+ +WSE+G+EG+++FL 
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  636  RVWRLFVSEDGSLNDKISNEGGSDEFNRTWHKTLKKVTEDLDALRFNTAISQLMIFTNDA  695
            RV RL+ + +         E  S+ +++  + T+K VTE++D ++FNTAI+QLM+F N A
Sbjct  663  RVYRLITTKE-------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAA  715

Query  696  YKADHLPRAAMENFVQMLSPLAPHLAEELWQ-LLGHNESITYAAWPAYDEAWTVDAEVEI  754
             K D L       FVQ+++P+APHL+EELWQ L +  ESI+Y +WP+YDE+  V+ +VEI
Sbjct  716  NKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEI  775

Query  755  VVQVNGKILQRATIAKDLDAKAMEAFALSLDNVQQALAGKTVRKVIAVPGKLVNIV  810
            VVQ++GK+  +  +AKDL    ++  AL+ ++VQ  +AGK + KVIAVP KLVNIV
Sbjct  776  VVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIV  831

291) leuS in NC_006582


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  889 bits (3366),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 553/838 (66%), Positives = 661/838 (79%), Gaps = 46/838 (5%)

Query  3    FSHQEIEKKWQAFWEENKTFKTDEQAEGPHFYALDMFPYPSGAGLHVGHPEGYTATDILA  62
            + H  IE KWQAFW +N TFKT+ +A  P FYALDMFPYPSGAGLHVGHPEGYTATDIL+
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMKRMQGYNVLHPMGWDAFGLPAEQYALDTGKHPATFTKQNIDTFKRQIKELGFSYDWDR  122
            R KR QG NVLHPMGWDAFGLPAEQYA+DTG++PA FT +NI  FKRQI+ LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EISTTDPHYYKWTQWIFLKLYEKGLAYIDEVAVNWCPALGTVLANEEIV-DGVSERGGHP  181
            E++TTDP+YYKWTQWIF KLYEKGLAY  EV+VNW   LGT +ANEE++ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRPMKQWVLRITAYAerlledleelewpeslKDMQRNWIGKSEGAEVTFKINE--HSV  239
            V R+PM+QW+L+ITAYAERLLEDLEE++WPES+KDMQRNWIGKS GA+VTFK+++     
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  240  NVFTTRPDTLFGATYMVLAPEHKLVTEITTDEQKEAVEAYQKQVALKSDIERTDLAKEKT  299
             VFTTRPDTLFGATY VLAPEH LV  ITT +Q EAV  Y++Q +LKSD+ RTDLAKEKT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  300  GAFTGAYAINPVNGEKIPVWIADYVLISYGTGAVMAVPAHDERDFEFANAFGLPIKEVVA  359
            G  TG+YAINPVNG  +PVWIADYVL SYGTGA+MAVPAHDERD EFA+ F L I  V+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  360  GGDVSKAAYTGDGEHVNSDFLNGLNKQEAVEKMIVWLEENGAGQRKVTYRLRDWLFSRQR  419
            GG+V  AA+T DG H+NSDFL+GL+K  A+ KM+ WLE +G G+ +VTYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  420  YWGEPIPIIHWEDGSMSALDESELPLVLPDLEEIKPSGTGESPLANAKDWLEVVDPKTGM  479
            YWGEPIPIIHWEDG+ +A+ ESELPLVLP   +I+PSGTGESPLAN  DWLEV     G+
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT-REDGV  482

Query  480  RGRRETNTMPQWAGSCWYYLRYIDPTNDEALADPEKLKNWLPVDTYIGGAEHAVLHLLYA  539
            +GRRETNTMPQWAGS WYYLRYIDP N E LAD E LK+WLPVD Y+GGAEHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  540  RFWHKFLYDIGVVPTKEPFQKVFNQGMILG------------------------------  569
            RFWHK LYD+GVVPTKEPFQK+FNQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  570  ---ENNEKMSKSKGNVVNPDEIIASHGADTLRLYEMFMGPLDASVAWSTNGLDGSRRFLE  626
               +   KMSKS  NVVNPD+++   GADTLR+YEMFMGPLDAS+AWS +GL+GSR+FL+
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  627  RVWRLIVNEETGKLNSNVKDVEGNEAFVRTYHQTVKKVTEDFAELRFNTGISQLMVFVNE  686
            RV RLI   E           E + A+ + Y++TVK VTE+  +++FNT+I+QLMVFVN 
Sbjct  663  RVYRLITTKEITE--------ENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNA  714

Query  687  GNKQEVLPKALIEGFVKLLSPVAPHIAEELWEKL-GHTDTITYEAWPTYDESLLveneve  745
            +NK++ L      GFV+L++P APH++EELW+ L +  ++I+Y +WP+YDES LVEN+VE
Sbjct  715  ANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVE  774

Query  746  vvvQMNGKVKTKLVINKGASKEEMEAAALADEKVQAAIGEKTIRKVIAVPGKLVNIVV  803
            +VVQ++GKVK+KLV+ K+ S+EE++  ALA+EKVQA I+ K I KVIAVP KLVNIV+
Sbjct  775  IVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

292) leuS in NC_014106


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  889 bits (3367),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 525/822 (64%), Positives = 652/822 (80%), Gaps = 45/822 (5%)

Query  2    YNHKVVEKKWQDYWAKHDTFKTGTDPDKKNYYALDMFPFPSGKGLHVGHPEGYTATDIVS  61
            Y+H  +E KWQ +WA ++TFKTGTD+ K ++YALDMFP+PSG GLHVGHPEGYTATDI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  62   RMKRAQGYNVLHPMGWDAFGLPTEQYALKTGEDPEVVTKNNIANFKRQLNKLGFSYDWDR  121
            R KRAQG NVLHPMGWDAFGLP+EQYA+ TG+DP   T +NIANFKRQ+N LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  122  EVTTSDPNYYKWTQWVFEQMYKKGLAYEAEVPVNWSPDLGTVVANEEVI-DGKTERGGYP  180
            EV T+DPNYYKWTQW+F ++Y KGLAYEAEVPVNW  +LGT +ANEEV+ DG +ERGGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  181  VYRKNMRQWMLKMTAYAdrlledlddldWPEPVKEMQRNWIGRSEGAQVTFKVKDSDKTF  240
            V RK MRQWMLK+TAYA+RLLEDL+++DWPE++K+MQRNWIG+S GA+VTFKVKD+DK F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  DVFTTRPDTLFGCSYTVLAPESKLVQEITTPEQKEAVDAYIKKIESKSDLERTDLNKDKT  300
             VFTTRPDTLFG +Y+VLAPE  LV+ ITT++Q EAV  Y ++   KSDL RTDL K+KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  301  GVFTGAYAINPVNGKEVPIWISDYVLASYGTGAVMAVPAHDDRDYAFATKFGLPINPVIE  360
            GV TG+YAINPVNGKE+P+WI+DYVLASYGTGA+MAVPAHD+RD  FA +F L I PV+E
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  361  GGNIEKEAFTGNGKHINSEFLDDLDNEEAKKRMIEWLEDHNCGKKKVNYKLRDWDFSRQR  420
            GGN+E  AFT +G HINS+FLD+LD+  A  +M+EWLE +  G+ +V Y+LRDW FSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  421  YWGEPIPVIHWEDGTTSLVPEDQLPLRLPHATDIKPSGTPESPLANLTDWVNVVDENGRK  480
            YWGEPIP+IHWEDGT++ VPE +LPL LP + DI+PSGT ESPLAN+TDW++V  E+G K
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  481  GKRETNTMPNWAGSSWYYLRYVDPHNDKELADYDLLKKWLPVDLYIGGAEHAVRHLLYAR  540
            G+RETNTMP+WAGSSWYYLRY+DPHN   LAD +LLK+WLPVD+Y+GGAEHAV HLLYAR
Sbjct  484  GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYAR  543

Query  541  FWHKVLYDLGVVPTKEPFQKLYNQGLIL--------------------------------  568
            FWHKVLYDLGVVPTKEPFQKL+NQG+IL                                
Sbjct  544  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEE  603

Query  569  --KNHEKMSKSKGNVVNPDEVIDEYGADSLRMYEMFMGPLDASIDWDDNGPASTKKFLDR  626
              +   KMSKS  NVVNPD+V+++YGAD+LR+YEMFMGPLDASI W ++G  +++KFLDR
Sbjct  604  LEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR  663

Query  627  VWRLFVNDLDLKAIPQERIVDKNDGELDKVYAETVKKVSEDFESLHFNTAISQMMVFMNA  686
            V RL         I    I + N G LDKVY ETVK V+E+ + + FNTAI+Q+MVF+NA
Sbjct  664  VYRL---------ITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNA  714

Query  687  AQKAKTIPREYAEGFVKLLAPVAPHMMEEIWQVF-GHDESITYAKWPTYDPAKLVESTVE  745
            A+K   +  +YA GFV+L+AP APH+ EE+WQ + + +ESI+Y  WP+YD +KLVE+ VE
Sbjct  715  ANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVE  774

Query  746  IMVQVNGKLRGKFQAPKDADRDDLQKQAMEIEHVKKFLEGKD  787
            I+VQ++GK+++K+  +KD  R++LQ  A+  E V+  + GKD
Sbjct  775  IVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKD  816

293) leuS in NC_018528


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  889 bits (3367),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 524/822 (64%), Positives = 653/822 (80%), Gaps = 45/822 (5%)

Query  2    YNHKAVEKKWQDYWAKHDTFKTGTDPKKKNYYALDMFPFPSGKGLHVGHPEGYTATDIVS  61
            Y+H A+E KWQ +WA ++TFKTGTD+ K ++YALDMFP+PSG GLHVGHPEGYTATDI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  62   RMKRAQGYNVLHPMGWDAFGLPTEQYALKTGEDPAVVTKNNIANFKRQLNKLGFSYDWDR  121
            R KRAQG NVLHPMGWDAFGLP+EQYA+ TG+DPA  T +NIANFKRQ+N LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  122  EITTSDPNYYKWTQWVFEQMYKKGLAYEAEVPVNWSPDLGTVVANEEVI-DGKTERGGYP  180
            E+ T+DPNYYKWTQW+F ++Y KGLAYEAEVPVNW  +LGT +ANEEV+ DG +ERGGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  181  VYRRNMRQWMLKMTAYAdrlledlddldWPEPVKEMQRNWIGRSVGAQVTFKIKDSDKTF  240
            V R+ MRQWMLK+TAYA+RLLEDL+++DWPE++K+MQRNWIG+S GA+VTFK+KD+DK F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  DIFTTRPDTLFGCSYTVLAPENKLVQEITTDGHRDEVNAYIKKIESKSDLERTDLNKDKT  300
             +FTTRPDTLFG +Y+VLAPE+ LV+ ITT ++ + V  Y ++   KSDL RTDL K+KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  301  GVFTGAYAINPVNGKEVPIWISDYVLASYGTGAVMAVPAHDDRDYAFAKKFDLPINQVLE  360
            GV TG+YAINPVNGKE+P+WI+DYVLASYGTGA+MAVPAHD+RD  FAK+F+L I  VLE
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  361  GGDLSKAAFTEDGPHINSEFLNGLNIKDAKKKMVDWLEEHNCGEKKVNYKLRDWDFSRQR  420
            GG++  AAFTEDG HINS+FL+GL+   A  KMV+WLE +  G+ +V Y+LRDW FSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  421  YWGEPIPVIHWEDGTTSLVPEDQLPLRLPHATDIKPSGTPESPLANLTDWVNVVDENGRK  480
            YWGEPIP+IHWEDGT++ VPE +LPL LP + DI+PSGT ESPLAN+TDW++V  E+G K
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  481  GKRETNTMPNWAGSSWYYLRYVDPHNDKELADYDLLKQWLPVDLYIGGAEHAVRHLLYAR  540
            G+RETNTMP+WAGSSWYYLRY+DPHN   LAD +LLKQWLPVD+Y+GGAEHAV HLLYAR
Sbjct  484  GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYAR  543

Query  541  FWHKVLYDLGVVPTKEPFQRLYNQGLIL--------------------------------  568
            FWHKVLYDLGVVPTKEPFQ+L+NQG+IL                                
Sbjct  544  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEE  603

Query  569  --KNHEKMSKSKGNVVNPDEVIDEYGADSLRMYEMFMGPLDASIDWDDNGPASTKKFLDR  626
              +   KMSKS  NVVNPD+V+++YGAD+LR+YEMFMGPLDASI W ++G  +++KFLDR
Sbjct  604  LEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR  663

Query  627  VWRLFVNDLDLKAIPQERIVDKNDGELDKVYAETVKKVTEDFDALHFNTAISQMMVFINA  686
            V RL         I    I + N G LDKVY ETVK VTE+ D + FNTAI+Q+MVF+NA
Sbjct  664  VYRL---------ITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNA  714

Query  687  AQKAKTIPREYVEGFVKLLAPVAPHMMEEIWQVF-GHDESITYAKWPTYDPAKLVESAVE  745
            A+K   +  +Y  GFV+L+AP APH+ EE+WQ + + +ESI+Y  WP+YD +KLVE+ VE
Sbjct  715  ANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVE  774

Query  746  IMVQVNGKLRGKFEAAKDADRDDVQKQAMALPHVQKFLEGKD  787
            I+VQ++GK+++K+  AKD  R+++Q  A+A   VQ  + GKD
Sbjct  775  IVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKD  816

294) leuS in NC_015975


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  888 bits (3364),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 551/837 (66%), Positives = 663/837 (80%), Gaps = 42/837 (5%)

Query  3    YDHKAIEKKWQHYWEEHKTFKTSEDPDKKKFYALDMFPYPSGQGLHVGHPEGYTATDIIS  62
            YDH AIE KWQ +W ++ TFKT+ D+ K KFYALDMFPYPSG GLHVGHPEGYTATDI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMKRMQGYDVLHPMGWDAFGLPAEQYALKTGNSPREFTKKNINNFRRQIKSLGLSYDWDR  122
            R KR QG +VLHPMGWDAFGLPAEQYA+ TGN P EFT  NI NF+RQI++LG+SYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVNTTDPSYYKWTQWIFEQMYKKGLAYEAEIPVNWCQELGTVVANEEII-DGKTERGGYP  181
            EVNTTDP+YYKWTQWIF ++Y KGLAYEAE+PVNW +ELGT +ANEE++ DG +ERGGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VVRKPMRQWVLKITAYAdrliddlddldWPEAIKDQQRNWIGRSVGASVKFSVCGHDDKQ  241
            VVRKPMRQW+LKITAYA+RL++DL+++DWPE+IKD QRNWIG+S GA+V F V  + DK+
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKV-KDTDKD  242

Query  242  IEVFTTRPDTLFGASLLVLAPEHEYVSSLTTAEQKEAVEAYVDQCAHKSDLERTDLAKTK  301
            + VFTTRPDTLFGA+  VLAPEH  V ++TT++Q EAV  Y  Q + KSDL RTDLAK K
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEK  302

Query  302  TGVFTGSYCINPVNGEKLPIWIADYVLASYGTGAIMVVPAHDERDYEFAKKFDLPIKPVI  361
            TGV TGSY INPVNG  +P+WIADYVLASYGTGAIM VPAHDERD EFAK+F+L I PV+
Sbjct  303  TGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL  362

Query  362  EGGNVEEAAYTGDGKHINSGFLDGLGKKEAIDKMVEWLEEKGIGKKKVNYRLRDWTFSRQ  421
            EGGNVEEAA+T DG HINS+FLDGL+K  AI KMVEWLE  G+G+ +V YRLRDW FSRQ
Sbjct  363  EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQ  422

Query  422  RYWGEPIPVIHWEDGETTLVPEDELPLRLPKATDIKPSGTGESPLANLDDWVNVVDKNGR  481
            RYWGEPIP+IHWEDG +T VPE ELPL LP + DI+PSGTGESPLAN+ DW++V   +G 
Sbjct  423  RYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGV  482

Query  482  KGRRETNTMPQWAGSSWYFLRYVDPHNQGKLADYDKLKHWMAVDLYVGGAEHAVLHLLYA  541
            KGRRETNTMPQWAGSSWY+LRY+DPHN  KLAD + LK+W++VD+YVGGAEHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKFLYDLGVVPTKEPFQKLVNQGMILGNN----------------------------  573
            RFWHK LYDLGVVPTKEPFQKL NQGMILG +                            
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  574  -----HEKMSKSKGNVINPDDIVEQYGADTLRLYEMFMGPLEASKPWSEDGLNGAYKFIN  628
                   KMSKS  NV+NPDD+VEQYGADTLR+YEMFMGPL+AS +WSE+GL+G+ KF++
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RIWNLIIDEDDNMRDRITTINEGELDFAYNQTVKKVTEDFTKMHFNTAISQMMVFVNDCY  688
            R+  LI   +      IT  N G LD  YN+TVK VTE+  +M FNTAI+Q+MVFVN   
Sbjct  663  RVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  689  KADSLPLEYVEGFVKLLAPLVPHLAEELWTKIGHVG-SIAYAKWPEYDESKLVKDevevv  747
            K D L  +Y  GFV+L+AP+ PHL+EELW  +   G SI+Y  WP YDESKLV ++VE+V
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  748  vqvngrvrqHLKVSSSISKEELEKFAMADEHVKEFVEGKNVVRVISVPGKLVNIVVK  804
            VQ++G+V+  L V+  +S+EEL+  A+A+E V+  + GK++++VI+VP KLVNIV+K
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

295) leuS in NC_017481


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  888 bits (3362),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 540/836 (65%), Positives = 659/836 (79%), Gaps = 42/836 (5%)

Query  3    YKHIEIEKKWQRYWeehktfkttedddkkNYYALDMFPYPSGQGLHVGHPEGYTATDIMA  62
            Y H  IE KWQ +W ++ TFKT  D  K ++YALDMFPYPSG GLHVGHPEGYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMKRMQGYNVLHPMGWDAFGLPAEQYALNTGNSPREFTKKNVNNFRRQIKSLGLSYDWDR  122
            R KR QG NVLHPMGWDAFGLPAEQYA++TGN P EFT  N+ NF+RQI++LG+SYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVNTTDPAYYKWTQWIFEQLYKKGLAYEAEVPVNWSPDLGTVVANEEVI-DGKTERGGFP  181
            EVNTTDP YYKWTQWIF +LY KGLAYEAEVPVNW  +LGT +ANEEV+ DG +ERGG+P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VIRKPMRQWVLKITAYAdrliddlddldWPEAIKEQQRNWIGRSVGAAINFPVSGDENTK  241
            V+RKPMRQW+LKITAYA+RL++DL+++DWPE+IK+ QRNWIG+S GA + F V  D +  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVK-DTDKD  242

Query  242  IEVFSTRPDTIFGVAALVLAPEHELVKQLTTPEHENEVEAYIEKISHKSDLERTDLAKDK  301
            + VF+TRPDT+FG +  VLAPEH LV  +TT+++ + V  Y  + S KSDL RTDLAK+K
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEK  302

Query  302  TGVFTGSYVVNPVSGEKLPIWIADYVLNSYGTGAVMVVPAHDERDHEFAQKFDLPIVQVI  361
            TGV TGSY +NPV+G  +P+WIADYVL SYGTGA+M VPAHDERD EFA++F+L I+ V+
Sbjct  303  TGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL  362

Query  362  EGGDVQKEAYTGDGVHINSDFLNGMDKEEAIDAINNWLEENGVGEKKVNYRLRDWLFSRQ  421
            EGG+V+  A+T DG+HINSDFL+G+DK  AI  + +WLE +GVG+ +V YRLRDWLFSRQ
Sbjct  363  EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQ  422

Query  422  RYWGEPIPVIHWEDGETTLVPEDELPLYLPKATDIKPSGTGESPLANLDDWVNVVDENGR  481
            RYWGEPIP+IHWEDG +T VPE ELPL LP + DI+PSGTGESPLAN+ DW++V  E+G 
Sbjct  423  RYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGV  482

Query  482  KGRRETNTMPQWAGSSWYFLRYIDPHNNHEVADYEKLKEWLPVNLYVGGAEHAVLHLLYA  541
            KGRRETNTMPQWAGSSWY+LRYIDPHN + +AD E LK+WLPV++YVGGAEHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKFLYDLGVVPTKEPFQKLVNQGMILGSN----------------------------  573
            RFWHK LYDLGVVPTKEPFQKL NQGMILG++                            
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  574  -----HEKMSKSKGNVVNPDDIVEQYGADTLRLYEMFMGPLDASIPWSEEGLGGAHKFIN  628
                   KMSKS  NVVNPDD+VEQYGADTLR+YEMFMGPLDASI+WSEEGL G++KF++
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RVWNLLIDENDNLRDRVTTINNHDLDKIYNETVKKVTEDYEAMHFNTAISQLMVFVNNAY  688
            RV  L+   +      +T  N+  LDK+YNETVK VTE+ + M FNTAI+QLMVFVN A 
Sbjct  663  RVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  689  KADSLPLEYVEGLVKLLSPVVPHITEELWSKLGHVG-SIAYAKWPTYDESKLVEDVVEIV  747
            K D L  +Y  G+V+L++P  PH+ EELW  L   G SI+Y  WP+YDESKLVE+ VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  748  VQINGKVRQHLQVSKDASREELQALALNDERIKQELADKEVKKVIAVPGKLVSIVV  803
            VQI+GKV+  L V+KD SREELQ +AL +E+++ E+A+K++ KVIAVP KLV+IV+
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

296) leuS in NC_007929


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  888 bits (3364),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 540/836 (65%), Positives = 659/836 (79%), Gaps = 42/836 (5%)

Query  3    YKHIEIEKKWQRYWeehktfkttedddkkNYYALDMFPYPSGQGLHVGHPEGYTATDIMA  62
            Y H  IE KWQ +W ++ TFKT  D  K ++YALDMFPYPSG GLHVGHPEGYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMKRMQGYNVLHPMGWDAFGLPAEQYALNTGNSPREFTKKNVNNFRRQIKSLGLSYDWDR  122
            R KR QG NVLHPMGWDAFGLPAEQYA++TGN P EFT  N+ NF+RQI++LG+SYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVNTTDPAYYKWTQWIFEQLYKKGLAYEAEVPVNWSPDLGTVVANEEVI-DGKTERGGFP  181
            EVNTTDP YYKWTQWIF +LY KGLAYEAEVPVNW  +LGT +ANEEV+ DG +ERGG+P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VIRKPMRQWVLKITAYAdrliddlddldWPEAIKEQQRNWIGRSVGAAINFPVSGDENTK  241
            V+RKPMRQW+LKITAYA+RL++DL+++DWPE+IK+ QRNWIG+S GA + F V  D +  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVK-DTDKD  242

Query  242  IEVFSTRPDTIFGVAALVLAPEHELVKQLTTPEHENEVEAYIEKISHKSDLERTDLAKDK  301
            + VF+TRPDT+FG +  VLAPEH LV  +TT+++ + V  Y  + S KSDL RTDLAK+K
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEK  302

Query  302  TGVFTGSYVVNPVSGEKLPIWIADYVLNSYGTGAVMVVPAHDERDHEFAQKFDLPIVQVI  361
            TGV TGSY +NPV+G  +P+WIADYVL SYGTGA+M VPAHDERD EFA++F+L I+ V+
Sbjct  303  TGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL  362

Query  362  EGGDVQKEAYTGDGVHINSDFLNGMDKEEAIDAINNWLEENGVGEKKVNYRLRDWLFSRQ  421
            EGG+V+  A+T DG+HINSDFL+G+DK  AI  + +WLE +GVG+ +V YRLRDWLFSRQ
Sbjct  363  EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQ  422

Query  422  RYWGEPIPVIHWEDGETTLVPEDELPLYLPKATDIKPSGTGESPLANLDDWVNVVDENGR  481
            RYWGEPIP+IHWEDG +T VPE ELPL LP + DI+PSGTGESPLAN+ DW++V  E+G 
Sbjct  423  RYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGV  482

Query  482  KGRRETNTMPQWAGSSWYFLRYIDPHNNHEIADYEKLKEWLPVNLYVGGAEHAVLHLLYA  541
            KGRRETNTMPQWAGSSWY+LRYIDPHN + +AD E LK+WLPV++YVGGAEHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKFLYDLGVVPTKEPFQKLVNQGMILGSN----------------------------  573
            RFWHK LYDLGVVPTKEPFQKL NQGMILG++                            
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  574  -----HEKMSKSKGNVVNPDDIVEQYGADTLRLYEMFMGPLDASIPWSEEGLGGAHKFIN  628
                   KMSKS  NVVNPDD+VEQYGADTLR+YEMFMGPLDASI+WSEEGL G++KF++
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RVWNLLIDENDNLRDRVTTINNHDLDKIYNETVKKVTEDYEAMHFNTAISQLMVFVNNAY  688
            RV  L+   +      +T  N+  LDK+YNETVK VTE+ + M FNTAI+QLMVFVN A 
Sbjct  663  RVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  689  KADSLPLEYVEGLVKLLSPVVPHITEELWSKLGHVG-SIAYAKWPTYDESKLVEDVVEIV  747
            K D L  +Y  G+V+L++P  PH+ EELW  L   G SI+Y  WP+YDESKLVE+ VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  748  VQINGKVRQHLQVSKDASREELQALALNDERIKQELADKEVKKVIAVPGKLVSIVV  803
            VQI+GKV+  L V+KD SREELQ +AL +E+++ E+A+K++ KVIAVP KLV+IV+
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

297) leuS in NC_014483


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  888 bits (3362),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 528/836 (64%), Positives = 662/836 (80%), Gaps = 43/836 (5%)

Query  10   YQPQSIEPKWQKYWDENKTFRTGEEPGKPKFYALDMFPYPSGAGLHVGHPEGYTATDIVS  69
            Y+  +IEPKWQ +W +N TF+TG +++KPKFYALDMFPYPSGAGLHVGHPEGYTATDI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  70   RYKRMRGYNVLHPMGWDAFGLPAEQHALDTGEHPREITVKNVNNFRRQIKSLGFSYDWDR  129
            R+KR +G NVLHPMGWDAFGLPAEQ A+DTG++P E+T  N+ NF+RQI++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  130  EISTTDPDYYKWTQWIFIQLYKRGLAYVAEVPVNWCPALGTVLANEEVI-DGKSERGGHP  188
            E++TTDP+YYKWTQWIF +LY +GLAY AEVPVNW   LGT +ANEEV+ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  189  VVRKPMRQWMLKITEYAdrlledleeldWSESIKDMQRNWIGKSTGAEVRFPIQGYDEQL  248
            VVRKPMRQWMLKIT YA+RLLEDLEE+DW+ESIKDMQRNWIGKSTGA+V F +++ D ++
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  249  TVFTTRPDTLFGASYCVLAPEQELVDIITTPEQKDAVQQYREQAARKSDLERTDLAKDKT  308
            TVFTTRPDTLFGA+Y VLAPE+ LVD ITT++Q +AV +Y+ QA+ KSDL RTDLAK+KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  309  GVFTGAYAVNPVNGEKLPIWIADYVLAGYGTGAIMAVPAHDARDWEFAKQFGLNIIEVVQ  368
            GV TG+YA+NPVNG  +P+WIADYVLA+YGTGAIMAVPAHD RDWEFAKQF L+II V++
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  369  GGDVANEPYTEDGPHVNSGPLNGLTNEEAIPKMIEWLEAEGKGHGKVTYRLRDWLFSRQR  428
            GG+V + ++TEDG H+NS+ L+GL +  AI+KM+EWLEAEG G+ +VTYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  429  YWGEPIPVIHLEDGTIKTVPEDQLPLVLPEMDNIKPSGTGESPLANATDWVETIDPETGM  488
            YWGEPIP+IH EDGT  +VPE +LPLVLP   +I+PSGTGESPLAN TDW+E +  E G+
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE-VTREDGV  482

Query  489  KARRETNTMPQWAGSCWYYLRFIDPKNDKELVSKEKQREWMPVDLYIGGAEHAVLHLLYA  548
            K+RRETNTMPQWAGS WYYLR+IDP N   L   E  ++W+PVD+Y+GGAEHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  549  RFWHKVLYDIGVVETKEPFYKLVNQGMILGNN----------------------------  580
            RFWHKVLYD+GVV TKEPF KL NQGMILG +                            
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  581  -----NEKMSKSRGNVINPDDIVNTFGADTLRIYEMFMGPLEATKPWNENGVEGAHRFLS  635
                   KMSKS  NV+NPDD+V+ +GADTLR+YEMFMGPL+A+ +W+E+G+EG+++FL 
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  636  RVWRLFVSEDGSLNDKITNDGGSDEFNRTWHKTLKKVTEDLDALRFNTAISQLMIFTNDA  695
            RV RL       +  K   +  S+ +++  + T+K VTE++D ++FNTAI+QLM+F N A
Sbjct  663  RVYRL-------ITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAA  715

Query  696  YKADLLPRAAMENFVQMLSPLAPHLAEELWQ-LLGHNDSITYAAWPAYDEAWTVDAEVEI  754
             K D L       FVQ+++P+APHL+EELWQ L +  +SI+Y +WP+YDE+  V+ +VEI
Sbjct  716  NKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEI  775

Query  755  VVQVNGKIVQRATIAKDLDAKAMEAFAVSLDNVQQALAGKTIRKVIAVPGKLVNIV  810
            VVQ++GK+  +  +AKDL    ++  A++ ++VQ  +AGK I KVIAVP KLVNIV
Sbjct  776  VVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIV  831

298) leuS in NC_010080


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  887 bits (3358),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 523/822 (64%), Positives = 651/822 (80%), Gaps = 45/822 (5%)

Query  2    YNHKVVEKKWQDYWAKHDTFKTGTDPKKKNYYALDMFPFPSGKGLHVGHPEGYTATDIVS  61
            Y+H  +E KWQ +WA ++TFKTGTD+ K ++YALDMFP+PSG GLHVGHPEGYTATDI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  62   RMKRAQGYNVLHPMGWDAFGLPTEQYALKTGEDPAVVTKNNIANFKRQLNKLGFSYDWDR  121
            R KRAQG NVLHPMGWDAFGLP+EQYA+ TG+DPA  T +NIANFKRQ+N LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  122  EITTSDPNYYKWTQWVFEQMYKKGLAYEAEVPVNWSPDLGTVVANEEVI-DGKTERGGYP  180
            E+ T+DPNYYKWTQW+F ++Y KGLAYEAEVPVNW  +LGT +ANEEV+ DG +ERGGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  181  VYRRNMRQWMLKMTAYAdrlledlddldWPEPVKEMQRNWIGRSVGAQVTFKIKDSDKTF  240
            V R+ MRQWMLK+TAYA+RLLEDL+++DWPE++K+MQRNWIG+S GA+VTFK+KD+DK F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  DIFTTRPDTLFGCSYTVLAPENKLVQEITTDGHRDEVNAYIKKIESKSDLERTDLNKDKT  300
             +FTTRPDTLFG +Y+VLAPE+ LV+ ITT ++ + V  Y ++   KSDL RTDL K+KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  301  GVFTGAYAINPVNGKEVPIWISDYVLASYGTGAVMAVPAHDDRDYAFAKKFDLPINQVLE  360
            GV TG+YAINPVNGKE+P+WI+DYVLASYGTGA+MAVPAHD+RD  FAK+F+L I  VLE
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  361  GGDLSKAAFTEDGPHINSEFLNGLNIKDAKKKMVDWLEEHNCGEKKVNYKLRDWDFSRQR  420
            GG++  AAFTEDG HINS+FL+GL+   A  KMV+WLE +  G+ +V Y+LRDW FSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  421  YWGEPIPVIHWEDGTTSLVPEDQLPLRLPHATDIKPSGTPESPLANLTDWVNVVDEMGRK  480
            YWGEPIP+IHWEDGT++ VPE +LPL LP + DI+PSGT ESPLAN+TDW++V  E G K
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  481  GKRETNTMPNWAGSSWYYLRYVDPHNDKELADYDLLKQWLPVDLYIGGAEHAVRHLLYAR  540
            G+RETNTMP+WAGSSWYYLRY+DPHN   LAD +LLKQWLPVD+Y+GGAEHAV HLLYAR
Sbjct  484  GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYAR  543

Query  541  FWHKVLYDLGVVPTKEPFQRLYNQGLIL--------------------------------  568
            FWHKVLYDLGVVPTKEPFQ+L+NQG+IL                                
Sbjct  544  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEE  603

Query  569  --KNHEKMSKSKGNVVNPDEVIDEYGADSLRMYEMFMGPLDASIDWDDNGPASTKKFLDR  626
              +   KMSKS  NVVNPD+V+++YGAD+LR+YEMFMGPLDASI W ++G  +++KFLDR
Sbjct  604  LEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR  663

Query  627  VWRLFVNDLDLKAIPQERIVDKNDGELDKVYAETVKKVTEDFDALHFNTAISQMMVFINA  686
            V RL         I    I + N G LDKVY ETVK VTE+ D + FNTAI+Q+MVF+NA
Sbjct  664  VYRL---------ITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNA  714

Query  687  AQKAKTIPREYVEGFVKLLAPVAPHMMEEIWQVF-GHDESITYAKWPTYDPAKLVESTVE  745
            A+K   +  +Y  GFV+L+AP APH+ EE+WQ + + +ESI+Y  WP+YD +KLVE+ VE
Sbjct  715  ANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVE  774

Query  746  IMVQVNGKLRGKFEAAKDADRDDVQKQAMALPHVQKFLEGKD  787
            I+VQ++GK+++K+  AKD  R+++Q  A+A   VQ  + GKD
Sbjct  775  IVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKD  816

299) leuS in NC_008526


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  886 bits (3355),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 520/812 (65%), Positives = 646/812 (80%), Gaps = 41/812 (5%)

Query  3    YDHHEIDKKWQRYWAEHNEFNTTTDPKKPNYYALDMFPYPSGQGLHVGHPEGYTATDIVA  62
            YDH  I+ KWQ +WA+++ F+T TD+ KP++YALDMFPYPSG GLHVGHPEGYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMKRMQGFNVLHPMGWDAFGLPAEQYALNTGHNPKTFTKQNIETFKRQINSLGFSYDWNR  122
            R KR QG NVLHPMGWDAFGLPAEQYA++TG++P  FT +NI  FKRQIN+LGFSYDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EINTTDPNYYKWTQWIFEQLYKHGLAYEAEVPVNWSPDLGTVVANEEVI-DGKTERGGFP  181
            E+NTTDPNYYKWTQWIF +LY  GLAYEAEVPVNW  +LGT +ANEEV+ DG +ERGG+P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VVRKPMRQWMLKITAYAEKLLTDLDDLDWPESIKQMQRNWIGKSTGAQITFRVTDSHEPF  241
            VVRKPMRQWMLKITAYAE+LL DL+++DWPESIK+MQRNWIGKSTGA++TF+V D++  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  DVFTTRPDTLFGATYVVMAPEHELVQKITTPAQQAVVDAYIDEAAHKSDLDRTALDKEKT  301
             VFTTRPDTLFGATY V+APEH LV+ ITT+ Q   V  Y  +A+ KSDL RT L KEKT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVWTGAYATNPVNGEKLPIWISDYVLASYGTGAIMSVPAHDDRDYAFAKKFGIEIKPVIE  361
            GVWTG+YA NPVNG  +P+WI+DYVLASYGTGAIM+VPAHD+RD  FAK+F ++I PV+E
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGNVDEAAYTGDGVHINSGFLDGLNEHDAIDRMIKWLEDKGIGSAKINYKLRDWVFSRQR  421
            GGNV+EAA+T DG+HINS+FLDGL+   AI +M+ WLE  G+G+ ++ Y+LRDW+FSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPVIHWEDGettlvpedelpltlpeeADIKPSGTGESPLANLTDWVNVVDKNGRK  481
            YWGEPIP+IHWEDG +T VPE ELPL LP   DI+PSGTGESPLAN+TDW++V   +G K
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  482  GKRETNTMPQWAGSSWYFLRFVDPHNKEALADYDKLKAWMPVDLYIGGAEHAVLHLLYAR  541
            G+RETNTMPQWAGSSWY+LR++DPHN E LAD + LK W+PVD+Y+GGAEHAVLHLLYAR
Sbjct  484  GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYAR  543

Query  542  FWNLFLYDIGAIPNKEPFQRLFNQGMILG-------------------------------  570
            FW+  LYD+G +P KEPFQ+LFNQGMILG                               
Sbjct  544  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEE  603

Query  571  --DNHEKMSKSKGNVVNPDDVVDEYGADTLRLYEMFMGPLDAGIAWSTKGLAGARKFLDR  628
              +   KMSKS  NVVNPDDVV++YGADTLR+YEMFMGPLDA+IAWS  GL G+RKFLDR
Sbjct  604  LEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR  663

Query  629  VWSAFIDDEGKLRDRITTINDGRLDKVYNETVKKVTEDYDALHFNTAISQMMVFINSARK  688
            V   +   E      IT  N G LDKVYNETVK VTE+ D + FNTAI+Q+MVF+N+A K
Sbjct  664  VYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANK  717

Query  689  DDDLPLEYVEGFVKMLAPIAPHLMEEIWSRL-GHDHSLTYAPWPSYDESKIKTDTYDMMI  747
            +D L  +Y  GFV+++AP+APHL EE+W  L + ++S++Y PWPSYDESK+  +  ++++
Sbjct  718  EDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVV  777

Query  748  QVNGKLRGSITADVNESDDEIKQAALANDNVQ  779
            Q++GK+++ +    + S +E+++ ALAN++VQ
Sbjct  778  QIKGKVKAKLVVAKDLSREELQEVALANEKVQ  809

300) LCBD_0930 in NC_017474


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  886 bits (3355),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 520/812 (65%), Positives = 646/812 (80%), Gaps = 41/812 (5%)

Query  3    YDHHEIDKKWQRYWAEHNEFNTTTDPKKPNYYALDMFPYPSGQGLHVGHPEGYTATDIVA  62
            YDH  I+ KWQ +WA+++ F+T TD+ KP++YALDMFPYPSG GLHVGHPEGYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMKRMQGFNVLHPMGWDAFGLPAEQYALNTGHNPKTFTKQNIETFKRQINSLGFSYDWNR  122
            R KR QG NVLHPMGWDAFGLPAEQYA++TG++P  FT +NI  FKRQIN+LGFSYDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EINTTDPNYYKWTQWIFEQLYKHGLAYEAEVPVNWSPDLGTVVANEEVI-DGKTERGGFP  181
            E+NTTDPNYYKWTQWIF +LY  GLAYEAEVPVNW  +LGT +ANEEV+ DG +ERGG+P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VVRKPMRQWMLKITAYAEKLLTDLDDLDWPESIKQMQRNWIGKSTGAQITFRVTDSHEPF  241
            VVRKPMRQWMLKITAYAE+LL DL+++DWPESIK+MQRNWIGKSTGA++TF+V D++  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  DVFTTRPDTLFGATYVVMAPEHELVQKITTPAQQAVVDAYIDEAAHKSDLDRTALDKEKT  301
             VFTTRPDTLFGATY V+APEH LV+ ITT+ Q   V  Y  +A+ KSDL RT L KEKT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVWTGAYATNPVNGEKLPIWISDYVLASYGTGAIMSVPAHDDRDYAFAKKFGIEIKPVIE  361
            GVWTG+YA NPVNG  +P+WI+DYVLASYGTGAIM+VPAHD+RD  FAK+F ++I PV+E
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGNVDEAAYTGDGVHINSGFLDGLNEHDAIDRMIKWLEDKGIGSAKINYKLRDWVFSRQR  421
            GGNV+EAA+T DG+HINS+FLDGL+   AI +M+ WLE  G+G+ ++ Y+LRDW+FSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPVIHWEDGettlvpedelpltlpeeADIKPSGTGESPLANLTDWVNVVDKNGRK  481
            YWGEPIP+IHWEDG +T VPE ELPL LP   DI+PSGTGESPLAN+TDW++V   +G K
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  482  GKRETNTMPQWAGSSWYFLRFVDPHNKEALADYDKLKAWMPVDLYIGGAEHAVLHLLYAR  541
            G+RETNTMPQWAGSSWY+LR++DPHN E LAD + LK W+PVD+Y+GGAEHAVLHLLYAR
Sbjct  484  GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYAR  543

Query  542  FWNLFLYDIGAIPNKEPFQRLFNQGMILG-------------------------------  570
            FW+  LYD+G +P KEPFQ+LFNQGMILG                               
Sbjct  544  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEE  603

Query  571  --DNHEKMSKSKGNVVNPDDVVDEYGADTLRLYEMFMGPLDAGIAWSTKGLAGARKFLDR  628
              +   KMSKS  NVVNPDDVV++YGADTLR+YEMFMGPLDA+IAWS  GL G+RKFLDR
Sbjct  604  LEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR  663

Query  629  VWSAFIDDEGKLRDRITTINDGRLDKVYNETVKKVTEDYDALHFNTAISQMMVFINSARK  688
            V   +   E      IT  N G LDKVYNETVK VTE+ D + FNTAI+Q+MVF+N+A K
Sbjct  664  VYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANK  717

Query  689  DDDLPLEYVEGFVKMLAPIAPHLMEEIWSRL-GHDHSLTYAPWPSYDESKIKTDTYDMMI  747
            +D L  +Y  GFV+++AP+APHL EE+W  L + ++S++Y PWPSYDESK+  +  ++++
Sbjct  718  EDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVV  777

Query  748  QVNGKLRGSITADVNESDDEIKQAALANDNVQ  779
            Q++GK+++ +    + S +E+++ ALAN++VQ
Sbjct  778  QIKGKVKAKLVVAKDLSREELQEVALANEKVQ  809

301) leuS in NC_010999


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  886 bits (3355),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 520/812 (65%), Positives = 646/812 (80%), Gaps = 41/812 (5%)

Query  3    YDHHEIDKKWQRYWAEHNEFNTTTDPKKPNYYALDMFPYPSGQGLHVGHPEGYTATDIVA  62
            YDH  I+ KWQ +WA+++ F+T TD+ KP++YALDMFPYPSG GLHVGHPEGYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMKRMQGFNVLHPMGWDAFGLPAEQYALNTGHNPKTFTKQNIETFKRQINSLGFSYDWNR  122
            R KR QG NVLHPMGWDAFGLPAEQYA++TG++P  FT +NI  FKRQIN+LGFSYDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EINTTDPNYYKWTQWIFEQLYKHGLAYEAEVPVNWSPDLGTVVANEEVI-DGKTERGGFP  181
            E+NTTDPNYYKWTQWIF +LY  GLAYEAEVPVNW  +LGT +ANEEV+ DG +ERGG+P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VVRKPMRQWMLKITAYAEKLLTDLDDLDWPESIKQMQRNWIGKSTGAQITFRVTDSHEPF  241
            VVRKPMRQWMLKITAYAE+LL DL+++DWPESIK+MQRNWIGKSTGA++TF+V D++  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  DVFTTRPDTLFGATYVVMAPEHELVQKITTPAQQAVVDAYIDEAAHKSDLDRTALDKEKT  301
             VFTTRPDTLFGATY V+APEH LV+ ITT+ Q   V  Y  +A+ KSDL RT L KEKT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVWTGAYATNPVNGEKLPIWISDYVLASYGTGAIMSVPAHDDRDYAFAKKFGIEIKPVIE  361
            GVWTG+YA NPVNG  +P+WI+DYVLASYGTGAIM+VPAHD+RD  FAK+F ++I PV+E
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGNVDEAAYTGDGVHINSGFLDGLNEHDAIDRMIKWLEDKGIGSAKINYKLRDWVFSRQR  421
            GGNV+EAA+T DG+HINS+FLDGL+   AI +M+ WLE  G+G+ ++ Y+LRDW+FSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPVIHWEDGettlvpedelpltlpeeADIKPSGTGESPLANLTDWVNVVDKNGRK  481
            YWGEPIP+IHWEDG +T VPE ELPL LP   DI+PSGTGESPLAN+TDW++V   +G K
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  482  GKRETNTMPQWAGSSWYFLRFVDPHNKEALADYDKLKAWMPVDLYIGGAEHAVLHLLYAR  541
            G+RETNTMPQWAGSSWY+LR++DPHN E LAD + LK W+PVD+Y+GGAEHAVLHLLYAR
Sbjct  484  GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYAR  543

Query  542  FWNLFLYDIGAIPNKEPFQRLFNQGMILG-------------------------------  570
            FW+  LYD+G +P KEPFQ+LFNQGMILG                               
Sbjct  544  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEE  603

Query  571  --DNHEKMSKSKGNVVNPDDVVDEYGADTLRLYEMFMGPLDAGIAWSTKGLAGARKFLDR  628
              +   KMSKS  NVVNPDDVV++YGADTLR+YEMFMGPLDA+IAWS  GL G+RKFLDR
Sbjct  604  LEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR  663

Query  629  VWSAFIDDEGKLRDRITTINDGRLDKVYNETVKKVTEDYDALHFNTAISQMMVFINSARK  688
            V   +   E      IT  N G LDKVYNETVK VTE+ D + FNTAI+Q+MVF+N+A K
Sbjct  664  VYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANK  717

Query  689  DDDLPLEYVEGFVKMLAPIAPHLMEEIWSRL-GHDHSLTYAPWPSYDESKIKTDTYDMMI  747
            +D L  +Y  GFV+++AP+APHL EE+W  L + ++S++Y PWPSYDESK+  +  ++++
Sbjct  718  EDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVV  777

Query  748  QVNGKLRGSITADVNESDDEIKQAALANDNVQ  779
            Q++GK+++ +    + S +E+++ ALAN++VQ
Sbjct  778  QIKGKVKAKLVVAKDLSREELQEVALANEKVQ  809

302) LC2W_0935 in NC_017473


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  886 bits (3355),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 520/812 (65%), Positives = 646/812 (80%), Gaps = 41/812 (5%)

Query  3    YDHHEIDKKWQRYWAEHNEFNTTTDPKKPNYYALDMFPYPSGQGLHVGHPEGYTATDIVA  62
            YDH  I+ KWQ +WA+++ F+T TD+ KP++YALDMFPYPSG GLHVGHPEGYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMKRMQGFNVLHPMGWDAFGLPAEQYALNTGHNPKTFTKQNIETFKRQINSLGFSYDWNR  122
            R KR QG NVLHPMGWDAFGLPAEQYA++TG++P  FT +NI  FKRQIN+LGFSYDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EINTTDPNYYKWTQWIFEQLYKHGLAYEAEVPVNWSPDLGTVVANEEVI-DGKTERGGFP  181
            E+NTTDPNYYKWTQWIF +LY  GLAYEAEVPVNW  +LGT +ANEEV+ DG +ERGG+P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VVRKPMRQWMLKITAYAEKLLTDLDDLDWPESIKQMQRNWIGKSTGAQITFRVTDSHEPF  241
            VVRKPMRQWMLKITAYAE+LL DL+++DWPESIK+MQRNWIGKSTGA++TF+V D++  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  DVFTTRPDTLFGATYVVMAPEHELVQKITTPAQQAVVDAYIDEAAHKSDLDRTALDKEKT  301
             VFTTRPDTLFGATY V+APEH LV+ ITT+ Q   V  Y  +A+ KSDL RT L KEKT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVWTGAYATNPVNGEKLPIWISDYVLASYGTGAIMSVPAHDDRDYAFAKKFGIEIKPVIE  361
            GVWTG+YA NPVNG  +P+WI+DYVLASYGTGAIM+VPAHD+RD  FAK+F ++I PV+E
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGNVDEAAYTGDGVHINSGFLDGLNEHDAIDRMIKWLEDKGIGSAKINYKLRDWVFSRQR  421
            GGNV+EAA+T DG+HINS+FLDGL+   AI +M+ WLE  G+G+ ++ Y+LRDW+FSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPVIHWEDGettlvpedelpltlpeeADIKPSGTGESPLANLTDWVNVVDKNGRK  481
            YWGEPIP+IHWEDG +T VPE ELPL LP   DI+PSGTGESPLAN+TDW++V   +G K
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  482  GKRETNTMPQWAGSSWYFLRFVDPHNKEALADYDKLKAWMPVDLYIGGAEHAVLHLLYAR  541
            G+RETNTMPQWAGSSWY+LR++DPHN E LAD + LK W+PVD+Y+GGAEHAVLHLLYAR
Sbjct  484  GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYAR  543

Query  542  FWNLFLYDIGAIPNKEPFQRLFNQGMILG-------------------------------  570
            FW+  LYD+G +P KEPFQ+LFNQGMILG                               
Sbjct  544  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEE  603

Query  571  --DNHEKMSKSKGNVVNPDDVVDEYGADTLRLYEMFMGPLDAGIAWSTKGLAGARKFLDR  628
              +   KMSKS  NVVNPDDVV++YGADTLR+YEMFMGPLDA+IAWS  GL G+RKFLDR
Sbjct  604  LEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR  663

Query  629  VWSAFIDDEGKLRDRITTINDGRLDKVYNETVKKVTEDYDALHFNTAISQMMVFINSARK  688
            V   +   E      IT  N G LDKVYNETVK VTE+ D + FNTAI+Q+MVF+N+A K
Sbjct  664  VYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANK  717

Query  689  DDDLPLEYVEGFVKMLAPIAPHLMEEIWSRL-GHDHSLTYAPWPSYDESKIKTDTYDMMI  747
            +D L  +Y  GFV+++AP+APHL EE+W  L + ++S++Y PWPSYDESK+  +  ++++
Sbjct  718  EDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVV  777

Query  748  QVNGKLRGSITADVNESDDEIKQAALANDNVQ  779
            Q++GK+++ +    + S +E+++ ALAN++VQ
Sbjct  778  QIKGKVKAKLVVAKDLSREELQEVALANEKVQ  809

303) leuS in NC_018641


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  886 bits (3355),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 520/812 (65%), Positives = 646/812 (80%), Gaps = 41/812 (5%)

Query  3    YDHHEIDKKWQRYWAEHNEFNTTTDPKKPNYYALDMFPYPSGQGLHVGHPEGYTATDIVA  62
            YDH  I+ KWQ +WA+++ F+T TD+ KP++YALDMFPYPSG GLHVGHPEGYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMKRMQGFNVLHPMGWDAFGLPAEQYALNTGHNPKTFTKQNIETFKRQINSLGFSYDWNR  122
            R KR QG NVLHPMGWDAFGLPAEQYA++TG++P  FT +NI  FKRQIN+LGFSYDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EINTTDPNYYKWTQWIFEQLYKHGLAYEAEVPVNWSPDLGTVVANEEVI-DGKTERGGFP  181
            E+NTTDPNYYKWTQWIF +LY  GLAYEAEVPVNW  +LGT +ANEEV+ DG +ERGG+P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VVRKPMRQWMLKITAYAEKLLTDLDDLDWPESIKQMQRNWIGKSTGAQITFRVTDSHEPF  241
            VVRKPMRQWMLKITAYAE+LL DL+++DWPESIK+MQRNWIGKSTGA++TF+V D++  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  DVFTTRPDTLFGATYVVMAPEHELVQKITTPAQQAVVDAYIDEAAHKSDLDRTALDKEKT  301
             VFTTRPDTLFGATY V+APEH LV+ ITT+ Q   V  Y  +A+ KSDL RT L KEKT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVWTGAYATNPVNGEKLPIWISDYVLASYGTGAIMSVPAHDDRDYAFAKKFGIEIKPVIE  361
            GVWTG+YA NPVNG  +P+WI+DYVLASYGTGAIM+VPAHD+RD  FAK+F ++I PV+E
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGNVDEAAYTGDGVHINSGFLDGLNEHDAIDRMIKWLEDKGIGSAKINYKLRDWVFSRQR  421
            GGNV+EAA+T DG+HINS+FLDGL+   AI +M+ WLE  G+G+ ++ Y+LRDW+FSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPVIHWEDGettlvpedelpltlpeeADIKPSGTGESPLANLTDWVNVVDKNGRK  481
            YWGEPIP+IHWEDG +T VPE ELPL LP   DI+PSGTGESPLAN+TDW++V   +G K
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  482  GKRETNTMPQWAGSSWYFLRFVDPHNKEALADYDKLKAWMPVDLYIGGAEHAVLHLLYAR  541
            G+RETNTMPQWAGSSWY+LR++DPHN E LAD + LK W+PVD+Y+GGAEHAVLHLLYAR
Sbjct  484  GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYAR  543

Query  542  FWNLFLYDIGAIPNKEPFQRLFNQGMILG-------------------------------  570
            FW+  LYD+G +P KEPFQ+LFNQGMILG                               
Sbjct  544  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEE  603

Query  571  --DNHEKMSKSKGNVVNPDDVVDEYGADTLRLYEMFMGPLDAGIAWSTKGLAGARKFLDR  628
              +   KMSKS  NVVNPDDVV++YGADTLR+YEMFMGPLDA+IAWS  GL G+RKFLDR
Sbjct  604  LEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR  663

Query  629  VWSAFIDDEGKLRDRITTINDGRLDKVYNETVKKVTEDYDALHFNTAISQMMVFINSARK  688
            V   +   E      IT  N G LDKVYNETVK VTE+ D + FNTAI+Q+MVF+N+A K
Sbjct  664  VYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANK  717

Query  689  DDDLPLEYVEGFVKMLAPIAPHLMEEIWSRL-GHDHSLTYAPWPSYDESKIKTDTYDMMI  747
            +D L  +Y  GFV+++AP+APHL EE+W  L + ++S++Y PWPSYDESK+  +  ++++
Sbjct  718  EDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVV  777

Query  748  QVNGKLRGSITADVNESDDEIKQAALANDNVQ  779
            Q++GK+++ +    + S +E+++ ALAN++VQ
Sbjct  778  QIKGKVKAKLVVAKDLSREELQEVALANEKVQ  809

304) leuS in NC_013504


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  886 bits (3356),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 526/815 (65%), Positives = 649/815 (80%), Gaps = 45/815 (5%)

Query  2    YNHKTVEKKWQKYWAEHDTFKTGTDPKKKNYYALDMFPFPSGKGLHVGHPEGYTATDIVS  61
            Y+H ++E KWQ +WA+++TFKTGTD+ K ++YALDMFP+PSG GLHVGHPEGYTATDI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  62   RMKRAQGYNVLHPMGWDAFGLPTEQYALKTGEDPEKVTKENIANFKKQLNKLGFSYDWDR  121
            R KRAQG NVLHPMGWDAFGLP+EQYA+ TG+DP   T ENIANFK+Q+N LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  122  EVTTSDPNYYKWTQWVFEQMYKKGLAYEAEVPVNWSPDLGTVVANEEII-DGKTERGGYP  180
            EV T+DPNYYKWTQW+F ++Y KGLAYEAEVPVNW  +LGT +ANEE++ DG +ERGGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  181  VYRRNMRQWMLKMTAYAdrlledlddldWPEPVKEMQRNWIGRSEGAQVTFKVKDSDKTF  240
            V R+ MRQWMLK+TAYA+RLLEDL+++DWPE++K+MQRNWIG+S GA+VTFKVKD+DK F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  DVFTTRPDTLFGVSYTVLAPESKLVQEITTSEQKEAVDAYIKKIESKSDLERTDLNKDKT  300
             VFTTRPDTLFG +Y+VLAPE  LV+ ITTS+Q EAV  Y ++   KSDL RTDL K+KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  301  GVFTGAYAVNPVNGKEVPIWISDYVLASYGTGAVMAVPAHDDRDYAFATKFGLPINRVIE  360
            GV TG+YA+NPVNGKE+P+WI+DYVLASYGTGA+MAVPAHD+RD  FA +F L I  V+E
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  361  GGNLEKEAFGGDGKHINSEFLDGLNNEEAKKRMIEWLEDHNVGEKKVNYKLRDWDFSRQR  420
            GGN+E  AF  DG HINS+FLDGL++  A  +M+EWLE + VG+ +V Y+LRDW FSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  421  YWGEPIPVIHWEDGTTSLVPEDELPLRLPHATDIKPSGTPESPLANLTDWVNVVDENGRK  480
            YWGEPIP+IHWEDGT++ VPE ELPL LP + DI+PSGT ESPLAN+TDW++V  E+G K
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  481  GKRETNTMPNWAGSSWYYLRYIDPHNDKELADYDLLKKWLPVDLYIGGAEHAVRHLLYAR  540
            G+RETNTMP+WAGSSWYYLRYIDPHN   LAD +LLK+WLPVD+Y+GGAEHAV HLLYAR
Sbjct  484  GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYAR  543

Query  541  FWHKVLYDLGVVPTKEPFQKLYNQGLIL--------------------------------  568
            FWHKVLYDLGVVPTKEPFQKL+NQG+IL                                
Sbjct  544  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEE  603

Query  569  --KNHEKMSKSKGNVVNPDEVIDEYGADSLRMYEMFMGPLDASIDWDDNGPASTKKFLDR  626
              +   KMSKS  NVVNPD+V+++YGAD+LR+YEMFMGPLDASI W ++G  +++KFLDR
Sbjct  604  LEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR  663

Query  627  VWRLFVNDLDLKAIPQEKIVDENDGELDKVYAETVKKVTEDFEALHFNTAISQMMVFMNA  686
            V RL         I    I +EN G LDKVY ETVK VTE+ + + FNTAI+Q+MVF+NA
Sbjct  664  VYRL---------ITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNA  714

Query  687  AQKAKIIPREYAEGFVQLLAPVAPHMMEEIWSVF-GHDESIAYAKWPEYDPAKLVESTVE  745
            A+K   +  +YA GFVQL+AP APH+ EE+W  + + +ESI+Y  WP YD +KLVE+ VE
Sbjct  715  ANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVE  774

Query  746  IMVQVNGKLRGKFKVAKDSDKDTLEKEALALDHVQ  780
            I+VQ++GK+++K+ VAKD  ++ L+  ALA + VQ
Sbjct  775  IVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQ  809

305) leuS in NC_017467


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  886 bits (3356),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 523/822 (64%), Positives = 651/822 (80%), Gaps = 45/822 (5%)

Query  2    YNHKVVEKKWQDYWAKHDTFKTGTDPKKKNYYALDMFPFPSGKGLHVGHPEGYTATDIVS  61
            Y+H  +E KWQ +WA ++TFKTGTD+ K ++YALDMFP+PSG GLHVGHPEGYTATDI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  62   RMKRAQGYNVLHPMGWDAFGLPTEQYALKTGEDPAVVTKNNIANFKRQLNKLGFSYDWDR  121
            R KRAQG NVLHPMGWDAFGLP+EQYA+ TG+DPA  T +NIANFKRQ+N LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  122  EITTSDPNYYKWTQWVFEQMYKKGLAYEAEVPVNWSPDLGTVVANEEVI-DGRTERGGYP  180
            E+ T+DPNYYKWTQW+F ++Y KGLAYEAEVPVNW  +LGT +ANEEV+ DG +ERGGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  181  VYRRNMRQWMLKMTAYAdrlledlddldWPEPVKEMQRNWIGRSVGAQVTFKIKDSDKTF  240
            V R+ MRQWMLK+TAYA+RLLEDL+++DWPE++K+MQRNWIG+S GA+VTFK+KD+DK F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  DIFTTRPDTLFGCSYTVLAPENKLVQEITTDGHRDEVNAYIKKIESKSDLERTDLNKDKT  300
             +FTTRPDTLFG +Y+VLAPE+ LV+ ITT ++ + V  Y ++   KSDL RTDL K+KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  301  GVFTGAYAINPVNGKEVPIWISDYVLASYGTGAVMAVPAHDDRDYAFAKKFDLPINQVLE  360
            GV TG+YAINPVNGKE+P+WI+DYVLASYGTGA+MAVPAHD+RD  FAK+F+L I  VLE
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  361  GGDLSKAAFTEDGPHINSEFLNGLNIKDAKKKMVDWLEEHNCGEKKVNYKLRDWDFSRQR  420
            GG++  AAFTEDG HINS+FL+GL+   A  KMV+WLE +  G+ +V Y+LRDW FSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  421  YWGEPIPVIHWEDGTTSLVPEDQLPLRLPHATDIKPSGTPESPLANLTDWVNVVDEMGRK  480
            YWGEPIP+IHWEDGT++ VPE +LPL LP + DI+PSGT ESPLAN+TDW++V  E G K
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  481  GKRETNTMPNWAGSSWYYLRYVDPHNDKELADYDLLKQWLPVDLYIGGAEHAVRHLLYAR  540
            G+RETNTMP+WAGSSWYYLRY+DPHN   LAD +LLKQWLPVD+Y+GGAEHAV HLLYAR
Sbjct  484  GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYAR  543

Query  541  FWHKVLYDLGVVPTKEPFQRLYNQGLIL--------------------------------  568
            FWHKVLYDLGVVPTKEPFQ+L+NQG+IL                                
Sbjct  544  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEE  603

Query  569  --KNHEKMSKSKGNVVNPDEVIDEYGADSLRMYEMFMGPLDASIDWDDNGPASTKKFLDR  626
              +   KMSKS  NVVNPD+V+++YGAD+LR+YEMFMGPLDASI W ++G  +++KFLDR
Sbjct  604  LEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR  663

Query  627  VWRLFVNDLDLKAIPQERIVDKNDGELDKVYAETVKKVTEDFDALHFNTAISQMMVFINA  686
            V RL         I    I + N G LDKVY ETVK VTE+ D + FNTAI+Q+MVF+NA
Sbjct  664  VYRL---------ITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNA  714

Query  687  AQKAKTIPREYVEGFVKLLAPVAPHMMEEIWQVF-GHDESITYAKWPTYDPAKLVESTVE  745
            A+K   +  +Y  GFV+L+AP APH+ EE+WQ + + +ESI+Y  WP+YD +KLVE+ VE
Sbjct  715  ANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVE  774

Query  746  IMVQVNGKLRGKFEAAKDADRDDVQKQAMALPHVQKFLEGKD  787
            I+VQ++GK+++K+  AKD  R+++Q  A+A   VQ  + GKD
Sbjct  775  IVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKD  816

306) LOCK919_0986 in NC_021721


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  885 bits (3353),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 520/812 (65%), Positives = 646/812 (80%), Gaps = 41/812 (5%)

Query  3    YDHHEIDKKWQRYWAEHNEFNTTTDPKKPNYYALDMFPYPSGQGLHVGHPEGYTATDIVA  62
            YDH  I+ KWQ +WA+++ F+T TD+ KP++YALDMFPYPSG GLHVGHPEGYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMKRMQGFNVLHPMGWDAFGLPAEQYALNTGHNPKTFTKQNIETFKRQINSLGFSYDWNR  122
            R KR QG NVLHPMGWDAFGLPAEQYA++TG++P  FT +NI  FKRQIN+LGFSYDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EINTTDPNYYKWTQWIFEQLYKHGLAYEAEVPVNWSPDLGTVVANEEVI-DGKTERGGFP  181
            E+NTTDPNYYKWTQWIF +LY  GLAYEAEVPVNW  +LGT +ANEEV+ DG +ERGG+P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VVRKPMRQWMLKITAYAEKLLTDLDDLDWPESIKQMQRNWIGKSTGAQITFRVTDSHEPF  241
            VVRKPMRQWMLKITAYAE+LL DL+++DWPESIK+MQRNWIGKSTGA++TF+V D++  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  DVFTTRPDTLFGATYVVMAPEHELVQKITTPAQQAVVDAYIDEAAHKSDLDRTALDKEKT  301
             VFTTRPDTLFGATY V+APEH LV+ ITT+ Q   V  Y  +A+ KSDL RT L KEKT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVWTGAYATNPVNGEKLPIWISDYVLASYGTGAIMSVPAHDDRDYAFAKKFGIEIKPVIE  361
            GVWTG+YA NPVNG  +P+WI+DYVLASYGTGAIM+VPAHD+RD  FAK+F ++I PV+E
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGNVDEAAYTGDGVHINSGFLDGLNEHDAIDRMIKWLEDKGIGSAKINYKLRDWVFSRQR  421
            GGNV+EAA+T DG+HINS+FLDGL+   AI +M+ WLE  G+G+ ++ Y+LRDW+FSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPVIHWEDGettlvpedelpltlpeeADIKPSGTGESPLANLTDWVNVVDKNGRK  481
            YWGEPIP+IHWEDG +T VPE ELPL LP   DI+PSGTGESPLAN+TDW++V   +G K
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  482  GKRETNTMPQWAGSSWYFLRFVDPHNKEALADYDKLKAWMPVDLYIGGAEHAVLHLLYAR  541
            G+RETNTMPQWAGSSWY+LR++DPHN E LAD + LK W+PVD+Y+GGAEHAVLHLLYAR
Sbjct  484  GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYAR  543

Query  542  FWNLFLYDIGAIPNKEPFQRLFNQGMILG-------------------------------  570
            FW+  LYD+G +P KEPFQ+LFNQGMILG                               
Sbjct  544  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEE  603

Query  571  --DNHEKMSKSKGNVVNPDDVVDEYGADTLRLYEMFMGPLDAGIAWSTKGLAGARKFLDR  628
              +   KMSKS  NVVNPDDVV++YGADTLR+YEMFMGPLDA+IAWS  GL G+RKFLDR
Sbjct  604  LEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR  663

Query  629  VWSAFIDDEGKLRDRITTINDGRLDKVYNETVKKVTEDYDALHFNTAISQMMVFINSARK  688
            V   +   E      IT  N G LDKVYNETVK VTE+ D + FNTAI+Q+MVF+N+A K
Sbjct  664  VYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANK  717

Query  689  DDDLPLEYVEGFVKMLAPIAPHLMEEIWSRL-GHDHSLTYAPWPSYDESKIKTDTYDMMI  747
            +D L  +Y  GFV+++AP+APHL EE+W  L + ++S++Y PWPSYDESK+  +  ++++
Sbjct  718  EDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVV  777

Query  748  QVNGKLRGSITADVNESDDEIKQAALANNNVQ  779
            Q++GK+++ +    + S +E+++ ALAN++VQ
Sbjct  778  QIKGKVKAKLVVAKDLSREELQEVALANEKVQ  809

307) LCAZH_0826 in NC_014334


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  885 bits (3353),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 520/812 (65%), Positives = 646/812 (80%), Gaps = 41/812 (5%)

Query  3    YDHHEIDKKWQRYWAEHNEFNTTTDPKKPNYYALDMFPYPSGQGLHVGHPEGYTATDIVA  62
            YDH  I+ KWQ +WA+++ F+T TD+ KP++YALDMFPYPSG GLHVGHPEGYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMKRMQGFNVLHPMGWDAFGLPAEQYALNTGHNPKTFTKQNIETFKRQINSLGFSYDWNR  122
            R KR QG NVLHPMGWDAFGLPAEQYA++TG++P  FT +NI  FKRQIN+LGFSYDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EINTTDPNYYKWTQWIFEQLYKHGLAYEAEVPVNWSPDLGTVVANEEVI-DGKTERGGFP  181
            E+NTTDPNYYKWTQWIF +LY  GLAYEAEVPVNW  +LGT +ANEEV+ DG +ERGG+P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VVRKPMRQWMLKITAYAEKLLTDLDDLDWPESIKQMQRNWIGKSTGAQITFRVTDSHEPF  241
            VVRKPMRQWMLKITAYAE+LL DL+++DWPESIK+MQRNWIGKSTGA++TF+V D++  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  DVFTTRPDTLFGATYVVMAPEHELVQKITTPAQQAVVDAYIDEAAHKSDLDRTALDKEKT  301
             VFTTRPDTLFGATY V+APEH LV+ ITT+ Q   V  Y  +A+ KSDL RT L KEKT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVWTGAYATNPVNGEKLPIWISDYVLASYGTGAIMSVPAHDDRDYAFAKKFGIEIKPVIE  361
            GVWTG+YA NPVNG  +P+WI+DYVLASYGTGAIM+VPAHD+RD  FAK+F ++I PV+E
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGNVDEAAYTGDGVHINSGFLDGLNEHDAIDRMIKWLEDKGIGSAKINYKLRDWVFSRQR  421
            GGNV+EAA+T DG+HINS+FLDGL+   AI +M+ WLE  G+G+ ++ Y+LRDW+FSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPVIHWEDGettlvpedelpltlpeeADIKPSGTGESPLANLTDWVNVVDKNGRK  481
            YWGEPIP+IHWEDG +T VPE ELPL LP   DI+PSGTGESPLAN+TDW++V   +G K
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  482  GKRETNTMPQWAGSSWYFLRFVDPHNKEALADYDKLKAWMPVDLYIGGAEHAVLHLLYAR  541
            G+RETNTMPQWAGSSWY+LR++DPHN E LAD + LK W+PVD+Y+GGAEHAVLHLLYAR
Sbjct  484  GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYAR  543

Query  542  FWNLFLYDIGAIPNKEPFQRLFNQGMILG-------------------------------  570
            FW+  LYD+G +P KEPFQ+LFNQGMILG                               
Sbjct  544  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEE  603

Query  571  --DNHEKMSKSKGNVVNPDDVVDEYGADTLRLYEMFMGPLDAGIAWSTKGLAGARKFLDR  628
              +   KMSKS  NVVNPDDVV++YGADTLR+YEMFMGPLDA+IAWS  GL G+RKFLDR
Sbjct  604  LEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR  663

Query  629  VWSAFIDDEGKLRDRITTINDGRLDKVYNETVKKVTEDYDALHFNTAISQMMVFINSARK  688
            V   +   E      IT  N G LDKVYNETVK VTE+ D + FNTAI+Q+MVF+N+A K
Sbjct  664  VYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANK  717

Query  689  DDDLPLEYVEGFVKMLAPIAPHLMEEIWSRL-GHDHSLTYAPWPSYDESKIKTDTYDMMI  747
            +D L  +Y  GFV+++AP+APHL EE+W  L + ++S++Y PWPSYDESK+  +  ++++
Sbjct  718  EDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVV  777

Query  748  QVNGKLRGSITADVNESDDEIKQAALANNNVQ  779
            Q++GK+++ +    + S +E+++ ALAN++VQ
Sbjct  778  QIKGKVKAKLVVAKDLSREELQEVALANEKVQ  809

308) LJP_0500 in NC_017477


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  885 bits (3353),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 524/815 (65%), Positives = 648/815 (80%), Gaps = 45/815 (5%)

Query  2    YNHKTVEKKWQKYWAEHDTFKTGTDPKKKNYYALDMFPFPSGKGLHVGHPEGYTATDIVS  61
            Y+H ++E KWQ +WA+++TFKTGTD+ K ++YALDMFP+PSG GLHVGHPEGYTATDI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  62   RMKRAQGYNVLHPMGWDAFGLPTEQYALKTGEDPEKVTKENIANFKKQLNKLGFSYDWDR  121
            R KRAQG NVLHPMGWDAFGLP+EQYA+ TG+DP   T ENIANFK+Q+N LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  122  EVTTSDPNYYKWTQWVFEQMYKKGLAYEAEVPVNWSPDLGTVVANEEII-DGKTERGGYP  180
            EV T+DPNYYKWTQW+F ++Y KGLAYEAEVPVNW  +LGT +ANEE++ DG +ERGGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  181  VYRRNMRQWMLKMTAYAdrlledlddldWPEPVKEMQRNWIGRSEGAQVTFKVKDSDKTF  240
            V R+ MRQWMLK+TAYA+RLLEDL+++DWPE++K+MQRNWIG+S GA+VTFKVKD+DK F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  DVFTTRPDTLFGVSYTVLAPESKLVQEITTPEQKEAVDAYIKKIESKSDLERTDLNKDKT  300
             VFTTRPDTLFG +Y+VLAPE  LV+ ITT++Q EAV  Y ++   KSDL RTDL K+KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  301  GVFTGAYAVNPVNGKEVPIWISDYVLASYGTGAVMAVPAHDDRDYAFATKFGLPINRVIE  360
            GV TG+YA+NPVNGKE+P+WI+DYVLASYGTGA+MAVPAHD+RD  FA +F L I  V+E
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  361  GGNLEKEAFGGDGKHINSEFLDGLNNEEAKKRMIEWLEDHNVGEKKVNYKLRDWDFSRQR  420
            GGN+E  AF  DG HINS+FLDGL++  A  +M+EWLE + VG+ +V Y+LRDW FSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  421  YWGEPIPVIHWEDGTTSLVPEDELPLRLPHATDIKPSGTPESPLANLTDWVNVVDENGRK  480
            YWGEPIP+IHWEDGT++ VPE ELPL LP + DI+PSGT ESPLAN+TDW++V  E+G K
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  481  GKRETNTMPNWAGSSWYYLRYIDPHNDKELADYDLLKKWLPVDLYIGGAEHAVRHLLYAR  540
            G+RETNTMP+WAGSSWYYLRYIDPHN   LAD +LLK+WLPVD+Y+GGAEHAV HLLYAR
Sbjct  484  GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYAR  543

Query  541  FWHKVLYDLGVVPTKEPFQKLYNQGLIL--------------------------------  568
            FWHKVLYDLGVVPTKEPFQKL+NQG+IL                                
Sbjct  544  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEE  603

Query  569  --KNHEKMSKSKGNVVNPDEVIDEYGADSLRMYEMFMGPLDASIDWDDNGPASTKKFLDR  626
              +   KMSKS  NVVNPD+V+++YGAD+LR+YEMFMGPLDASI W ++G  +++KFLDR
Sbjct  604  LEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR  663

Query  627  VWRLFVNDLDLKAIPQEKIVDENDGELDKVYAETVKKVTEDFEALHFNTAISQMMVFMNA  686
            V RL         I    I +EN G LDKVY ETVK VTE+ + + FNTAI+Q+MVF+NA
Sbjct  664  VYRL---------ITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNA  714

Query  687  AQKAKTIPREYAEGFVQLLAPVAPHMMEEIWSVF-GHDESIAYAKWPEYDPAKLVESTVE  745
            A+K   +  +YA GFVQL+AP APH+ EE+W  + + +ESI+Y  WP YD +KLVE+ VE
Sbjct  715  ANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVE  774

Query  746  IMVQVNGKLRGKFKAAKDSDKDTLEKEALALDHVQ  780
            I+VQ++GK+++K+  AKD  ++ L+  ALA + VQ
Sbjct  775  IVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQ  809

309) leuS in NC_005362


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  885 bits (3353),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 524/815 (65%), Positives = 648/815 (80%), Gaps = 45/815 (5%)

Query  2    YNHKTVEKKWQKYWAEHDTFKTGTDPKKKNYYALDMFPFPSGKGLHVGHPEGYTATDIVS  61
            Y+H ++E KWQ +WA+++TFKTGTD+ K ++YALDMFP+PSG GLHVGHPEGYTATDI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  62   RMKRAQGYNVLHPMGWDAFGLPTEQYALKTGEDPEKVTKENIANFKKQLNKLGFSYDWDR  121
            R KRAQG NVLHPMGWDAFGLP+EQYA+ TG+DP   T ENIANFK+Q+N LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  122  EVTTSDPNYYKWTQWVFEQMYKKGLAYEAEVPVNWSPDLGTVVANEEII-DGKTERGGYP  180
            EV T+DPNYYKWTQW+F ++Y KGLAYEAEVPVNW  +LGT +ANEE++ DG +ERGGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  181  VYRRNMRQWMLKMTAYAdrlledlddldWPEPVKEMQRNWIGRSEGAQVTFKVKDSDKTF  240
            V R+ MRQWMLK+TAYA+RLLEDL+++DWPE++K+MQRNWIG+S GA+VTFKVKD+DK F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  DVFTTRPDTLFGVSYTVLAPESKLVQEITTPEQKEAVDAYIKKIESKSDLERTDLNKDKT  300
             VFTTRPDTLFG +Y+VLAPE  LV+ ITT++Q EAV  Y ++   KSDL RTDL K+KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  301  GVFTGAYAVNPVNGKEVPIWISDYVLASYGTGAVMAVPAHDDRDYAFATKFGLPINRVIE  360
            GV TG+YA+NPVNGKE+P+WI+DYVLASYGTGA+MAVPAHD+RD  FA +F L I  V+E
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  361  GGNLEKEAFGGDGKHINSEFLDGLNNEEAKKRMIEWLEDHNVGEKKVNYKLRDWDFSRQR  420
            GGN+E  AF  DG HINS+FLDGL++  A  +M+EWLE + VG+ +V Y+LRDW FSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  421  YWGEPIPVIHWEDGTTSLVPEDELPLRLPHATDIKPSGTPESPLANLTDWVNVVDENGRK  480
            YWGEPIP+IHWEDGT++ VPE ELPL LP + DI+PSGT ESPLAN+TDW++V  E+G K
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  481  GKRETNTMPNWAGSSWYYLRYIDPHNDKELADYDLLKKWLPVDLYIGGAEHAVRHLLYAR  540
            G+RETNTMP+WAGSSWYYLRYIDPHN   LAD +LLK+WLPVD+Y+GGAEHAV HLLYAR
Sbjct  484  GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYAR  543

Query  541  FWHKVLYDLGVVPTKEPFQKLYNQGLIL--------------------------------  568
            FWHKVLYDLGVVPTKEPFQKL+NQG+IL                                
Sbjct  544  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEE  603

Query  569  --KNHEKMSKSKGNVVNPDEVIDEYGADSLRMYEMFMGPLDASIDWDDNGPASTKKFLDR  626
              +   KMSKS  NVVNPD+V+++YGAD+LR+YEMFMGPLDASI W ++G  +++KFLDR
Sbjct  604  LEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR  663

Query  627  VWRLFVNDLDLKAIPQEKIVDENDGELDKVYAETVKKVTEDFEALHFNTAISQMMVFMNA  686
            V RL         I    I +EN G LDKVY ETVK VTE+ + + FNTAI+Q+MVF+NA
Sbjct  664  VYRL---------ITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNA  714

Query  687  AQKAKTIPREYAEGFVQLLAPVAPHMMEEIWSVF-GHDESIAYAKWPEYDPAKLVESTVE  745
            A+K   +  +YA GFVQL+AP APH+ EE+W  + + +ESI+Y  WP YD +KLVE+ VE
Sbjct  715  ANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVE  774

Query  746  IMVQVNGKLRGKFKAAKDSDKDTLEKEALALDHVQ  780
            I+VQ++GK+++K+  AKD  ++ L+  ALA + VQ
Sbjct  775  IVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQ  809

310) LBPG_00010 in NC_022112


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  885 bits (3353),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 520/812 (65%), Positives = 646/812 (80%), Gaps = 41/812 (5%)

Query  3    YDHHEIDKKWQRYWAEHNEFNTTTDPKKPNYYALDMFPYPSGQGLHVGHPEGYTATDIVA  62
            YDH  I+ KWQ +WA+++ F+T TD+ KP++YALDMFPYPSG GLHVGHPEGYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMKRMQGFNVLHPMGWDAFGLPAEQYALNTGHNPKTFTKQNIETFKRQINSLGFSYDWNR  122
            R KR QG NVLHPMGWDAFGLPAEQYA++TG++P  FT +NI  FKRQIN+LGFSYDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EINTTDPNYYKWTQWIFEQLYKHGLAYEAEVPVNWSPDLGTVVANEEVI-DGKTERGGFP  181
            E+NTTDPNYYKWTQWIF +LY  GLAYEAEVPVNW  +LGT +ANEEV+ DG +ERGG+P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VVRKPMRQWMLKITAYAEKLLTDLDDLDWPESIKQMQRNWIGKSTGAQITFRVTDSHEPF  241
            VVRKPMRQWMLKITAYAE+LL DL+++DWPESIK+MQRNWIGKSTGA++TF+V D++  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  DVFTTRPDTLFGATYVVMAPEHELVQKITTPAQQAVVDAYIDEAAHKSDLDRTALDKEKT  301
             VFTTRPDTLFGATY V+APEH LV+ ITT+ Q   V  Y  +A+ KSDL RT L KEKT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVWTGAYATNPVNGEKLPIWISDYVLASYGTGAIMSVPAHDDRDYAFAKKFGIEIRPVIE  361
            GVWTG+YA NPVNG  +P+WI+DYVLASYGTGAIM+VPAHD+RD  FAK+F ++I PV+E
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGNVDEAAYTGDGVHINSGFLDGLNEHDAIDRMIKWLEDKGIGSAKINYKLRDWVFSRQR  421
            GGNV+EAA+T DG+HINS+FLDGL+   AI +M+ WLE  G+G+ ++ Y+LRDW+FSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPVIHWEDGettlvpedelpltlpeeADIKPSGTGESPLANLTDWVNVVDKNGRK  481
            YWGEPIP+IHWEDG +T VPE ELPL LP   DI+PSGTGESPLAN+TDW++V   +G K
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  482  GKRETNTMPQWAGSSWYFLRFVDPHNKEALADYDKLKAWMPVDLYIGGAEHAVLHLLYAR  541
            G+RETNTMPQWAGSSWY+LR++DPHN E LAD + LK W+PVD+Y+GGAEHAVLHLLYAR
Sbjct  484  GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYAR  543

Query  542  FWNLFLYDIGAIPNKEPFQRLFNQGMILG-------------------------------  570
            FW+  LYD+G +P KEPFQ+LFNQGMILG                               
Sbjct  544  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEE  603

Query  571  --DNHEKMSKSKGNVVNPDDVVDEYGADTLRLYEMFMGPLDAGIAWSTKGLAGARKFLDR  628
              +   KMSKS  NVVNPDDVV++YGADTLR+YEMFMGPLDA+IAWS  GL G+RKFLDR
Sbjct  604  LEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR  663

Query  629  VWSAFIDDEGKLRDRITTINDGRLDKVYNETVKKVTEDYDALHFNTAISQMMVFINSARK  688
            V   +   E      IT  N G LDKVYNETVK VTE+ D + FNTAI+Q+MVF+N+A K
Sbjct  664  VYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANK  717

Query  689  DDDLPLEYVEGFVKMLAPIAPHLMEEIWSRL-GHDHSLTYAPWPSYDESKIKTDTYDMMI  747
            +D L  +Y  GFV+++AP+APHL EE+W  L + ++S++Y PWPSYDESK+  +  ++++
Sbjct  718  EDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVV  777

Query  748  QVNGKLRGSITADVNESDDEIKQAALANNNVQ  779
            Q++GK+++ +    + S +E+++ ALAN++VQ
Sbjct  778  QIKGKVKAKLVVAKDLSREELQEVALANEKVQ  809

311) LA14_1608 in NC_021181


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  885 bits (3352),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 526/822 (64%), Positives = 649/822 (79%), Gaps = 45/822 (5%)

Query  2    YNHKVVEKKWQDYWAKHDTFKTGTDSNKKNYYALDMFPFPSGKGLHVGHPEGYTATDIVS  61
            Y+H  +E KWQ +WA ++TFKTGTD++K ++YALDMFP+PSG GLHVGHPEGYTATDI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  62   RMKRAQGYNVLHPMGWDAFGLPTEQYALKTGEDPEVVTKNNIANFKRQLNKLGFSYDWDR  121
            R KRAQG NVLHPMGWDAFGLP+EQYA+ TG+DP   T +NIANFKRQ+N LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  122  EVTTSDPNYYKWTQWVFEQMYKKGLAYEAEVPVNWSPDLGTVVANEEIV-DGKTERGGYP  180
            EV T+DPNYYKWTQW+F ++Y KGLAYEAEVPVNW  +LGT +ANEE++ DG +ERGGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  181  VYRRNMRQWMLKMTAYAdrlledlddldWPEPVKEMQRNWIGRSLGAQVTFKIKDSDKTF  240
            V R+ MRQWMLK+TAYA+RLLEDL+++DWPE++K+MQRNWIG+S GA+VTFK+KD+DK F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  DIFTTRPDTLFGCSYTVLAPENKLVQEITTDAQRDEVNAYIKKIESKSDLERTDLNKDKT  300
             +FTTRPDTLFG +Y+VLAPE+ LV+ ITT  Q + V  Y ++   KSDL RTDL K+KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  301  GVFTGAYAINPVNGKEVPIWISDYVLASYGTGAVMAVPAHDERDYAFATKFGLPINPVLE  360
            GV TG+YAINPVNGKE+P+WI+DYVLASYGTGA+MAVPAHDERD  FA +F L I PVLE
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  361  GGDITKEAFTEDGPHINSEFLNGLNIKDAKKKMVEWLEEHNCGEKKVNYKLRDWDFSRQR  420
            GG++   AFTEDG HINS+FL+GL+   A  KMVEWLE +  G+ +V Y+LRDW FSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  421  YWGEPIPVIHWEDGETTLVPEDQLPLRLPHATDIKPSGTPESPLANLTDWVNVVDENGRK  480
            YWGEPIP+IHWEDG +T VPE +LPL LP + DI+PSGT ESPLAN+TDW++V  E+G K
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  481  GKRETNTMPNWAGSSWYYLRYVDPHNDKELADYDLLKKWLPVDLYIGGAEHAVRHLLYAR  540
            G+RETNTMP+WAGSSWYYLRY+DPHN   LAD +LLK+WLPVD+Y+GGAEHAV HLLYAR
Sbjct  484  GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYAR  543

Query  541  FWHKVLYDLGVVPTKEPFQRLYNQGLIL--------------------------------  568
            FWHKVLYDLGVVPTKEPFQ+L+NQG+IL                                
Sbjct  544  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEE  603

Query  569  --KNHEKMSKSKGNVVNPDDVIDEYGADSLRMYEMFMGPLDASIDWDDNGPASTKKFLDR  626
              +   KMSKS  NVVNPDDV+++YGAD+LR+YEMFMGPLDASI W ++G  +++KFLDR
Sbjct  604  LEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR  663

Query  627  VWRLFVNDLDLKAIPQERIVDENDGELDKVYAETVKKVTEDFDALHFNTAISQMMVFMNA  686
            V RL         I    I +EN G LDKVY ETVK VTE+ D + FNTAI+Q+MVF+NA
Sbjct  664  VYRL---------ITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNA  714

Query  687  AQKAKTIPREYAEGFVKLLAPVAPHMMEEIWQVF-GHDESISYAEWSTYDPAKLVESTVE  745
            A+K   +  +YA GFV+L+AP APH+ EE+WQ + + +ESISY  W++YD +KLVE+ VE
Sbjct  715  ANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVE  774

Query  746  IMVQVNGKLRGKFQAAKDADRDEVQKQAMELPHVQKFLEGKD  787
            I+VQ++GK+++K+  AKD  R+E+Q  A+    VQ  + GKD
Sbjct  775  IVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKD  816

312) leuS in NC_006814


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  885 bits (3352),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 526/822 (64%), Positives = 649/822 (79%), Gaps = 45/822 (5%)

Query  2    YNHKVVEKKWQDYWAKHDTFKTGTDSNKKNYYALDMFPFPSGKGLHVGHPEGYTATDIVS  61
            Y+H  +E KWQ +WA ++TFKTGTD++K ++YALDMFP+PSG GLHVGHPEGYTATDI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  62   RMKRAQGYNVLHPMGWDAFGLPTEQYALKTGEDPEVVTKNNIANFKRQLNKLGFSYDWDR  121
            R KRAQG NVLHPMGWDAFGLP+EQYA+ TG+DP   T +NIANFKRQ+N LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  122  EVTTSDPNYYKWTQWVFEQMYKKGLAYEAEVPVNWSPDLGTVVANEEIV-DGKTERGGYP  180
            EV T+DPNYYKWTQW+F ++Y KGLAYEAEVPVNW  +LGT +ANEE++ DG +ERGGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  181  VYRRNMRQWMLKMTAYAdrlledlddldWPEPVKEMQRNWIGRSLGAQVTFKIKDSDKTF  240
            V R+ MRQWMLK+TAYA+RLLEDL+++DWPE++K+MQRNWIG+S GA+VTFK+KD+DK F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  DIFTTRPDTLFGCSYTVLAPENKLVQEITTDAQRDEVNAYIKKIESKSDLERTDLNKDKT  300
             +FTTRPDTLFG +Y+VLAPE+ LV+ ITT  Q + V  Y ++   KSDL RTDL K+KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  301  GVFTGAYAINPVNGKEVPIWISDYVLASYGTGAVMAVPAHDERDYAFATKFGLPINPVLE  360
            GV TG+YAINPVNGKE+P+WI+DYVLASYGTGA+MAVPAHDERD  FA +F L I PVLE
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  361  GGDITKEAFTEDGPHINSEFLNGLNIKDAKKKMVEWLEEHNCGEKKVNYKLRDWDFSRQR  420
            GG++   AFTEDG HINS+FL+GL+   A  KMVEWLE +  G+ +V Y+LRDW FSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  421  YWGEPIPVIHWEDGETTLVPEDQLPLRLPHATDIKPSGTPESPLANLTDWVNVVDENGRK  480
            YWGEPIP+IHWEDG +T VPE +LPL LP + DI+PSGT ESPLAN+TDW++V  E+G K
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  481  GKRETNTMPNWAGSSWYYLRYVDPHNDKELADYDLLKKWLPVDLYIGGAEHAVRHLLYAR  540
            G+RETNTMP+WAGSSWYYLRY+DPHN   LAD +LLK+WLPVD+Y+GGAEHAV HLLYAR
Sbjct  484  GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYAR  543

Query  541  FWHKVLYDLGVVPTKEPFQRLYNQGLIL--------------------------------  568
            FWHKVLYDLGVVPTKEPFQ+L+NQG+IL                                
Sbjct  544  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEE  603

Query  569  --KNHEKMSKSKGNVVNPDDVIDEYGADSLRMYEMFMGPLDASIDWDDNGPASTKKFLDR  626
              +   KMSKS  NVVNPDDV+++YGAD+LR+YEMFMGPLDASI W ++G  +++KFLDR
Sbjct  604  LEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR  663

Query  627  VWRLFVNDLDLKAIPQERIVDENDGELDKVYAETVKKVTEDFDALHFNTAISQMMVFMNA  686
            V RL         I    I +EN G LDKVY ETVK VTE+ D + FNTAI+Q+MVF+NA
Sbjct  664  VYRL---------ITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNA  714

Query  687  AQKAKTIPREYAEGFVKLLAPVAPHMMEEIWQVF-GHDESISYAEWSTYDPAKLVESTVE  745
            A+K   +  +YA GFV+L+AP APH+ EE+WQ + + +ESISY  W++YD +KLVE+ VE
Sbjct  715  ANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVE  774

Query  746  IMVQVNGKLRGKFQAAKDADRDEVQKQAMELPHVQKFLEGKD  787
            I+VQ++GK+++K+  AKD  R+E+Q  A+    VQ  + GKD
Sbjct  775  IVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKD  816

313) lhe_1588 in NC_021744


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  885 bits (3352),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 522/822 (64%), Positives = 650/822 (80%), Gaps = 45/822 (5%)

Query  2    YNHKVVEKKWQDYWAKHDTFKTGTDPKKKNYYALDMFPFPSGKGLHVGHPEGYTATDIVS  61
            Y+H  +E KWQ +WA ++TFKTGTD+ K ++YALDMFP+PSG GLHVGHPEGYTATDI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  62   RMKRAQGYNVLHPMGWDAFGLPTEQYALKTGEDPAVVTKNNIANFKRQLNKLGFSYDWDR  121
            R KRAQG NVLHPMGWDAFGLP+EQYA+ TG+DPA  T +NIANFKRQ+N LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  122  EITTSDPNYYKWTQWVFEQMYKKGLAYEAEVPVNWSPDLGTVVANEEVI-DGKTERGGYP  180
            E+ T+DPNYYKWTQW+F ++Y KGLAYEAEVPVNW  +LGT +ANEEV+ DG +ERGGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  181  VYRRNMRQWMLKMTAYAdrlledlddldWPEPVKEMQRNWIGRSVGAQVTFKIKDSDKTF  240
            V R+ MRQWMLK+TAYA+RLLEDL+++DWPE++K+MQRNWIG+S GA+VTFK+KD+DK F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  DIFTTRPDTLFGCSYTVLAPENKLVQEITTDGHRDEVNAYIKKIESKSDLERTDLNKDKT  300
             +FTTRPDTLFG +Y+VLAPE+ LV+ ITT ++ + V  Y ++   KSDL RTDL K+KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  301  GVFTGAYAINPVNGKKVPIWISDYVLASYGTGAVMAVPAHDDRDYAFAKKFDLPINQVLE  360
            GV TG+YAINPVNGK +P+WI+DYVLASYGTGA+MAVPAHD+RD  FAK+F+L I  VLE
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  361  GGDLSKAAFTEDGPHINSEFLNGLNIKDAKKKMVDWLEEHNCGEKKVNYKLRDWDFSRQR  420
            GG++  AAFTEDG HINS+FL+GL+   A  KMV+WLE +  G+ +V Y+LRDW FSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  421  YWGEPIPVIHWEDGTTSLVPEDQLPLRLPHATDIKPSGTPESPLANLTDWVNVVDEMGRK  480
            YWGEPIP+IHWEDGT++ VPE +LPL LP + DI+PSGT ESPLAN+TDW++V  E G K
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  481  GKRETNTMPNWAGSSWYYLRYVDPHNDKELADYDLLKQWLPVDLYIGGAEHAVRHLLYAR  540
            G+RETNTMP+WAGSSWYYLRY+DPHN   LAD +LLKQWLPVD+Y+GGAEHAV HLLYAR
Sbjct  484  GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYAR  543

Query  541  FWHKVLYDLGVVPTKEPFQRLYNQGLIL--------------------------------  568
            FWHKVLYDLGVVPTKEPFQ+L+NQG+IL                                
Sbjct  544  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEE  603

Query  569  --KNHEKMSKSKGNVVNPDEVIDEYGADSLRMYEMFMGPLDASIDWDDNGPASTKKFLDR  626
              +   KMSKS  NVVNPD+V+++YGAD+LR+YEMFMGPLDASI W ++G  +++KFLDR
Sbjct  604  LEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR  663

Query  627  VWRLFVNDLDLKAIPQERIVDKNDGELDKVYAETVKKVTEDFDALHFNTAISQMMVFINA  686
            V RL         I    I + N G LDKVY ETVK VTE+ D + FNTAI+Q+MVF+NA
Sbjct  664  VYRL---------ITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNA  714

Query  687  AQKAKTIPREYVEGFVKLLAPVAPHMMEEIWQVF-GHDESITYAKWPTYDPAKLVESTVE  745
            A+K   +  +Y  GFV+L+AP APH+ EE+WQ + + +ESI+Y  WP+YD +KLVE+ VE
Sbjct  715  ANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVE  774

Query  746  IMVQVNGKLRGKFEAAKDADRDDVQKQAMALPHVQKFLEGKD  787
            I+VQ++GK+++K+  AKD  R+++Q  A+A   VQ  + GKD
Sbjct  775  IVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKD  816

314) leuS in NC_017542


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  883 bits (3345),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 523/836 (63%), Positives = 660/836 (79%), Gaps = 43/836 (5%)

Query  10   YQPQSIEPKWQKYWDENKTFRTGEEPGKPKFYALDMFPYPSGAGLHVGHPEGYTATDIVS  69
            Y+  +IEPKWQ +W +N TF+TG +++KPKFYALDMFPYPSGAGLHVGHPEGYTATDI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  70   RYKRMRGYNVLHPMGWDAFGLPAEQHALDTGEHPREITVKNVNNFRRQIKSLGFSYDWDR  129
            R+KR +G NVLHPMGWDAFGLPAEQ A+DTG++P E+T  N+ NF+RQI++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  130  EISTTDPDYYKWTQWIFIQLYKRGLAYVAEVPVNWCPALGTVLANEEVI-DGKSERGGHP  188
            E++TTDP+YYKWTQWIF +LY +GLAY AEVPVNW   LGT +ANEEV+ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  189  VIRKPMRQWMLKITEYAdrllddleeldWSESIKDMQRNWIGKSTGAEVHFPIEGYDEQL  248
            V+RKPMRQWMLKIT YA+RLL+DLEE+DW+ESIKDMQRNWIGKSTGA+V F + + D ++
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  249  TVFTTRPDTLFGASYCVLAPEQELVDMITTPEQKDAVQQYREQAARKSDLERTDLAKDKT  308
            TVFTTRPDTLFGA+Y VLAPE+ LVD ITT++Q +AV +Y+ QA+ KSDL RTDLAK+KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  309  GVFTGAYAVNPVNGEKLPIWIADYVLAGYGTGAIMAVPGHDTRDWEFAKKFGLKITEVVQ  368
            GV TG+YA+NPVNG  +P+WIADYVLA+YGTGAIMAVP+HD RDWEFAK+F L I  V++
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  369  GGDVDKEPYTEDGPHVNSGLLNGLTNEEAIPKMIEWLEAEGKGQGKVTYRLRDWLFSRQR  428
            GG+V+  ++TEDG H+NS++L+GL +  AI+KM+EWLEAEG G+ +VTYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  429  YWGEPIPVIHLEDGTIKTVPEDQLPLVLPEMDNIKPSGTGESPLANATDWVEIVDPETGM  488
            YWGEPIP+IH EDGT  +VPE +LPLVLP   +I+PSGTGESPLAN TDW+E V  E G+
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE-VTREDGV  482

Query  489  KARRETNTMPQWAGSCWYYLRFIDPKNDKELVSKEKQREWMPVDLYIGGAEHAVLHLLYA  548
            K+RRETNTMPQWAGS WYYLR+IDP N   L   E  ++W+PVD+Y+GGAEHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  549  RFWHKVLYDIGVVETKEPFYKLVNQGMILGNN----------------------------  580
            RFWHKVLYD+GVV TKEPF KL NQGMILG +                            
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  581  -----NEKMSKSRGNVINPDDIVNTFGADTLRIYEMFMGPLEATKPWNENGVEGAHRFLS  635
                   KMSKS  NV+NPDD+V+ +GADTLR+YEMFMGPL+A+ +W+E+G+EG+++FL 
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  636  RVWRLFVSEDGSLNEKIKNDGGSDEFKRTWHKTLKKVTEDLDALRFNTAISQLMIFTNDA  695
            RV RL+ + + +       +  S+ + +  + T+K VTE++D ++FNTAI+QLM+F N A
Sbjct  663  RVYRLITTKEIT-------EENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAA  715

Query  696  YKADLLPRAAMENFVQMLSPLAPHLAEELWQ-LLGHNESITYAAWPAYDEAWTVDAEVEI  754
             K D L       FVQ+++P+APHL+EELWQ L +  ESI+Y +WP+YDE+  V+ +VEI
Sbjct  716  NKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEI  775

Query  755  VIQMNGKIVQRATIAKDLDAKAMEAFALSLDSVQEALAGKTVRKVIAVPGKLVNIV  810
            V+Q++GK+  +  +AKDL    ++  AL+ + VQ  +AGK + KVIAVP KLVNIV
Sbjct  776  VVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIV  831

315) PPSC2_c3659 in NC_014622


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  883 bits (3345),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 523/836 (63%), Positives = 660/836 (79%), Gaps = 43/836 (5%)

Query  10   YQPQSIEPKWQKYWDENKTFRTGEEPGKPKFYALDMFPYPSGAGLHVGHPEGYTATDIVS  69
            Y+  +IEPKWQ +W +N TF+TG +++KPKFYALDMFPYPSGAGLHVGHPEGYTATDI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  70   RYKRMRGYNVLHPMGWDAFGLPAEQHALDTGEHPREITVKNVNNFRRQIKSLGFSYDWDR  129
            R+KR +G NVLHPMGWDAFGLPAEQ A+DTG++P E+T  N+ NF+RQI++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  130  EISTTDPDYYKWTQWIFIQLYKRGLAYVAEVPVNWCPALGTVLANEEVI-DGKSERGGHP  188
            E++TTDP+YYKWTQWIF +LY +GLAY AEVPVNW   LGT +ANEEV+ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  189  VIRKPMRQWMLKITEYAdrllddleeldWSESIKDMQRNWIGKSTGAEVHFPIEGYDEQL  248
            V+RKPMRQWMLKIT YA+RLL+DLEE+DW+ESIKDMQRNWIGKSTGA+V F + + D ++
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  249  TVFTTRPDTLFGASYCVLAPEQELVDMITTPEQKDAVQQYREQAARKSDLERTDLAKDKT  308
            TVFTTRPDTLFGA+Y VLAPE+ LVD ITT++Q +AV +Y+ QA+ KSDL RTDLAK+KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  309  GVFTGAYAVNPVNGEKLPIWIADYVLAGYGTGAIMAVPGHDTRDWEFAKKFGLKITEVVQ  368
            GV TG+YA+NPVNG  +P+WIADYVLA+YGTGAIMAVP+HD RDWEFAK+F L I  V++
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  369  GGDVDKEPYTEDGPHVNSGLLNGLTNEEAIPKMIEWLEAEGKGQGKVTYRLRDWLFSRQR  428
            GG+V+  ++TEDG H+NS++L+GL +  AI+KM+EWLEAEG G+ +VTYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  429  YWGEPIPVIHLEDGTIKTVPEDQLPLVLPEMDNIKPSGTGESPLANATDWVEIVDPETGM  488
            YWGEPIP+IH EDGT  +VPE +LPLVLP   +I+PSGTGESPLAN TDW+E V  E G+
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE-VTREDGV  482

Query  489  KARRETNTMPQWAGSCWYYLRFIDPKNDKELVSKEKQREWMPVDLYIGGAEHAVLHLLYA  548
            K+RRETNTMPQWAGS WYYLR+IDP N   L   E  ++W+PVD+Y+GGAEHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  549  RFWHKVLYDIGVVETKEPFYKLVNQGMILGNN----------------------------  580
            RFWHKVLYD+GVV TKEPF KL NQGMILG +                            
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  581  -----NEKMSKSRGNVINPDDIVNTFGADTLRIYEMFMGPLEATKPWNENGVEGAHRFLS  635
                   KMSKS  NV+NPDD+V+ +GADTLR+YEMFMGPL+A+ +W+E+G+EG+++FL 
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  636  RVWRLFVSEDGSLNEKIKNDGGSDEFKRTWHKTLKKVTEDLDALRFNTAISQLMIFTNDA  695
            RV RL+ + + +       +  S+ + +  + T+K VTE++D ++FNTAI+QLM+F N A
Sbjct  663  RVYRLITTKEIT-------EENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAA  715

Query  696  YKADLLPRAAMENFVQMLSPLAPHLAEELWQ-LLGHNESITYAAWPAYDEAWTVDAEVEI  754
             K D L       FVQ+++P+APHL+EELWQ L +  ESI+Y +WP+YDE+  V+ +VEI
Sbjct  716  NKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEI  775

Query  755  VIQMNGKIVQRATIAKDLDAKAMEAFALSLDSVQEALAGKTVRKVIAVPGKLVNIV  810
            V+Q++GK+  +  +AKDL    ++  AL+ + VQ  +AGK + KVIAVP KLVNIV
Sbjct  776  VVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIV  831

316) leuS in NC_008054


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  882 bits (3341),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 514/795 (65%), Positives = 638/795 (81%), Gaps = 45/795 (5%)

Query  2    YNHKVVEKKWQKYWLENKTFKTGTDPEKPKYYVLDMFPYPSGKGLHVGHPEGYTATDIMA  61
            Y+H  +E KWQ +W +N TFKTGTD+ KPK+Y LDMFPYPSG GLHVGHPEGYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  62   RMKRAQGYNVLHPMGWDAFGLPAEQYALQTGNDPATFTDENIAHFKKQLQALGFSYDWDR  121
            R KRAQG NVLHPMGWDAFGLPAEQYA++TGNDPA FT ENIA+FK+Q++ALGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  122  EIKTTDPNYYKWTQWIFEQMYKMGLAYEAEVPVNWSPDLGTVVANEEVI-DGKTERGGYP  180
            E++TTDPNYYKWTQWIF ++Y  GLAYEAEVPVNW  +LGT +ANEEV+ DG +ERGGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  181  VYRRKMRQWMLKITAYAdrllddlddldWPEPIKEMQRNWIGRSVGAQVTFKIKDSDKSF  240
            V R+ MRQWMLKITAYA+RLL+DL+++DWPE+IK+MQRNWIG+S GA+VTFK+KD+DK F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  AVFTTRPDTLFGCSYTVLAPENELVKEITSPEQKEAVDAYIKSIESKSDLERTDLNKDKT  300
            +VFTTRPDTLFG +Y+VLAPE+ LV  IT+++Q EAV  Y +    KSDL RTDL K+KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  301  GVFTGAYAINPVNGEEVPVWISDYVLATYGTGAVMAVPAHDERDYAFATKFDLPIKEVVE  360
            GV TG+YAINPVNG E+PVWI+DYVLA+YGTGA+MAVPAHDERD  FA +F+L I  V+E
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  361  GGDISKEAFAGDGVHVNSDFLNGLHNEEAKAKMVDWLTEKGVGEKKVNYKMRDWNFSRQR  420
            GG++   AF+ DG+H+NSDFL+GL++  A AKMV+WL   GVG+ +V Y++RDW FSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  421  YWGEPIPVIHWEDGETTLVPEDELPLRLPKESNIKPSGTPESPLANLTDWVNVVDENGRK  480
            YWGEPIP+IHWEDG +T VPE ELPL LP   +I+PSGT ESPLAN+TDW++V  E+G K
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  481  GKRETNTMPQWAGSSWYFLRYIDPHNDKALADPELLKKWMPVDLYIGGAEHATLHLLYAR  540
            G+RETNTMPQWAGSSWY+LRYIDPHN   LAD ELLK+W+PVD+Y+GGAEHA LHLLYAR
Sbjct  484  GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYAR  543

Query  541  FWHKVLYDLGVVPTKEPFQKLYNQGLIL--------------------------------  568
            FWHKVLYDLGVVPTKEPFQKL+NQG+IL                                
Sbjct  544  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEE  603

Query  569  --KNHEKMSKSRGNVVNPDDVVDEYGADSLRTYEMFMGPLNASIDWDDNGPSGVKKFLDR  626
              +   KMSKS  NVVNPDDVV++YGAD+LR YEMFMGPL+ASI W ++G  G +KFLDR
Sbjct  604  LEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR  663

Query  627  VWRTFVNDLDLDPIPSEKITDKNDGKLDKIYNETVKTVTEHFEELRFNTAISQMMVFMNA  686
            V R          I +  IT+ N G LDK+YNETVK+VTE+ ++++FNTAI+Q+MVF+NA
Sbjct  664  VYRL---------ITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNA  714

Query  687  CQKVDKIPREYAEGFVKLMAPVAPHMMEEIWHVF-GHDESVQFAAWPTYDASKLVESTVE  745
             +K DK+  +YA GFV+L+AP APH+ EE+W+ + + +ES+ + +WP+YD SKLVE+ VE
Sbjct  715  ANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVE  774

Query  746  MAVTVNGKKRGNFQI  760
            + V ++GK ++++ +
Sbjct  775  IVVQIKGKVKAKLVV  789

317) LBU_1344 in NC_017469


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  880 bits (3333),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 513/795 (65%), Positives = 638/795 (81%), Gaps = 45/795 (5%)

Query  2    YNHKVVEKKWQKYWLENKTFKTGTDPEKPKYYVLDMFPYPSGKGLHVGHPEGYTATDIMA  61
            Y+H  +E KWQ +W +N TFKTGTD+ KPK+Y LDMFPYPSG GLHVGHPEGYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  62   RMKRAQGYNVLHPMGWDAFGLPAEQYALQTGNDPATFTDENIAHFKKQLQALGFSYDWDR  121
            R KRAQG NVLHPMGWDAFGLPAEQYA++TGNDPA FT ENIA+FK+Q++ALGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  122  EIKTTDPNYYKWTQWIFEQMYKMGLAYEAEVPVNWSPDLGTVVANEEVI-DGKTERGGYP  180
            E++TTDPNYYKWTQWIF ++Y  GLAYEAEVPVNW  +LGT +ANEEV+ DG +ERGGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  181  VYRRKMRQWMLKITAYAdrllddlddldWPEPIKEMQRNWIGRSVGAQVTFKIKDSDKSF  240
            V R+ MRQWMLKITAYA+RLL+DL+++DWPE+IK+MQRNWIG+S GA+VTFK+KD+DK F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  AVFTTRPDTLFGCSYTVLAPENELVKEITSPEQKEAVDAYIKSIESKSDLERTDLNKDKT  300
            +VFTTRPDTLFG +Y+VLAPE+ LV  IT+++Q EAV  Y +    KSDL RTDL K+KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  301  GVFTGAYAINPVNGEEVPVWISDYVLATYGTGAVMAVPAHDERDYSFATKFDLPIKEVVE  360
            GV TG+YAINPVNG E+PVWI+DYVLA+YGTGA+MAVPAHDERD  FA +F+L I  V+E
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  361  GGDISKEAFAGDGVHVNSDFLNGLHNEEAKAKMVDWLTEKGVGEKKVNYKMRDWNFSRQR  420
            GG++   AF+ DG+H+NSDFL+GL++  A AKMV+WL   GVG+ +V Y++RDW FSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  421  YWGEPIPVIHWEDGETTLVPEDELPLRLPKESNIKPSGTPESPLANLTDWVNVVDENGRK  480
            YWGEPIP+IHWEDG +T VPE ELPL LP   +I+PSGT ESPLAN+TDW++V  E+G K
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  481  GKRETNTMPQWAGSSWYFLRYIDPNNDKALADPELLKKWMPVDLYIGGAEHATLHLLYAR  540
            G+RETNTMPQWAGSSWY+LRYIDP+N   LAD ELLK+W+PVD+Y+GGAEHA LHLLYAR
Sbjct  484  GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYAR  543

Query  541  FWHKVLYDLGVVPTKEPFQKLYNQGLIL--------------------------------  568
            FWHKVLYDLGVVPTKEPFQKL+NQG+IL                                
Sbjct  544  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEE  603

Query  569  --KNHEKMSKSRGNVVNPDDVVDEYGADSLRTYEMFMGPLNASIDWDDNGPSGVKKFLDR  626
              +   KMSKS  NVVNPDDVV++YGAD+LR YEMFMGPL+ASI W ++G  G +KFLDR
Sbjct  604  LEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR  663

Query  627  VWRTFVNDLDLDPIPSEKITDKNDGKLDKIYNETVKTVTEHFEELRFNTAISQMMVFMNA  686
            V R          I +  IT+ N G LDK+YNETVK+VTE+ ++++FNTAI+Q+MVF+NA
Sbjct  664  VYRL---------ITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNA  714

Query  687  CQKVDKIPREYAEGFVKLMAPVAPHMMEEIWHVF-GHDESVQFAAWPTYDASKLVESTVE  745
             +K DK+  +YA GFV+L+AP APH+ EE+W+ + + +ES+ + +WP+YD SKLVE+ VE
Sbjct  715  ANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVE  774

Query  746  MAVTVNGKKRGNFQI  760
            + V ++GK ++++ +
Sbjct  775  IVVQIKGKVKAKLVV  789

318) leuS in NC_008529


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  880 bits (3334),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 513/795 (65%), Positives = 638/795 (81%), Gaps = 45/795 (5%)

Query  2    YNHKVVEKKWQKYWLENKTFKTGTDPEKPKYYVLDMFPYPSGKGLHVGHPEGYTATDIMA  61
            Y+H  +E KWQ +W +N TFKTGTD+ KPK+Y LDMFPYPSG GLHVGHPEGYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  62   RMKRAQGYNVLHPMGWDAFGLPAEQYALQTGNDPATFTDENIAHFKKQLQALGFSYDWDR  121
            R KRAQG NVLHPMGWDAFGLPAEQYA++TGNDPA FT ENIA+FK+Q++ALGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  122  EIKTTDPNYYKWTQWIFEQMYKMGLAYEAEVPVNWSPDLGTVVANEEVI-DGKTERGGYP  180
            E++TTDPNYYKWTQWIF ++Y  GLAYEAEVPVNW  +LGT +ANEEV+ DG +ERGGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  181  VYRRKMRQWMLKITAYAdrllddlddldWPEPIKEMQRNWIGRSVGAQVTFKIKDSDKSF  240
            V R+ MRQWMLKITAYA+RLL+DL+++DWPE+IK+MQRNWIG+S GA+VTFK+KD+DK F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  AVFTTRPDTLFGCSYTVLAPENELVKEITSPEQKEAVDAYIKSIESKSDLERTDLNKDKT  300
            +VFTTRPDTLFG +Y+VLAPE+ LV  IT+++Q EAV  Y +    KSDL RTDL K+KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  301  GVFTGAYAINPVNGEEVPVWISDYVLATYGTGAVIAVPAHDERDYAFATKFDLPIKEVVE  360
            GV TG+YAINPVNG E+PVWI+DYVLA+YGTGA++AVPAHDERD  FA +F+L I  V+E
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  361  GGDISKEAFAGDGVHVNSDFLNGLHNEEAKAKMVDWLTEKGVGEKKVNYKMRDWNFSRQR  420
            GG++   AF+ DG+H+NSDFL+GL++  A AKMV+WL   GVG+ +V Y++RDW FSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  421  YWGEPIPVIHWEDGETTLVPEDELPLRLPKESNIKPSGTPESPLANLTDWVNVVDENGRK  480
            YWGEPIP+IHWEDG +T VPE ELPL LP   +I+PSGT ESPLAN+TDW++V  E+G K
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  481  GKRETNTMPQWAGSSWYFLRYIDPHNDKALADPELLKKWMPVDLYIGGAEHATLHLLYAR  540
            G+RETNTMPQWAGSSWY+LRYIDPHN   LAD ELLK+W+PVD+Y+GGAEHA LHLLYAR
Sbjct  484  GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYAR  543

Query  541  FWHKVLYDLGVVPTKEPFQKLYNQGLIL--------------------------------  568
            FWHKVLYDLGVVPTKEPFQKL+NQG+IL                                
Sbjct  544  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEE  603

Query  569  --KNHEKMSKSRGNVVNPDDVVDEYGADSLRTYEMFMGPLNASIDWDDNGPSGVKKFLDR  626
              +   KMSKS  NVVNPDDVV++YGAD+LR YEMFMGPL+ASI W ++G  G +KFLDR
Sbjct  604  LEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR  663

Query  627  VWRTFVNDLDLDPIPSEKITDKNDGKLDKIYNETVKTVTEHFEELRFNTAISQMMVFMNA  686
            V R          I +  IT+ N G LDK+YNETVK+VTE+ ++++FNTAI+Q+MVF+NA
Sbjct  664  VYRL---------ITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNA  714

Query  687  CQKVDKIPREYAEGFVKLMAPVAPHMMEEIWHVF-GHDESVQFAAWPTYDASKLVESTVE  745
             +K DK+  +YA GFV+L+AP APH+ EE+W+ + + +ES+ + +WP+YD SKLVE+ VE
Sbjct  715  ANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVE  774

Query  746  MAVTVNGKKRGNFQI  760
            + V ++GK ++++ +
Sbjct  775  IVVQIKGKVKAKLVV  789

319) leuS in NC_014727


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  880 bits (3331),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 513/795 (65%), Positives = 636/795 (80%), Gaps = 45/795 (5%)

Query  2    YNHKVVEKKWQKYWLENKTFKTGTDPEKPKYYVLDMFPYPSGKGLHVGHPEGYTATDIMA  61
            Y+H  +E KWQ +W +N TFKTGTD+ KPK+Y LDMFPYPSG GLHVGHPEGYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  62   RMKRAQGYNVLHPMGWDAFGLPAEQYALQTGNDPATFTDKNIAHFKKQLQALGFSYDWDR  121
            R KRAQG NVLHPMGWDAFGLPAEQYA++TGNDPA FT  NIA+FK+Q++ALGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  122  EIKTTDPNYYKWTQWIFEQMYKMGLAYEAEVPVNWSPDLGTVVANEEVI-DGKTERGGYP  180
            E++TTDPNYYKWTQWIF ++Y  GLAYEAEVPVNW  +LGT +ANEEV+ DG +ERGGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  181  VYRRKMRQWMLKITAYAdrllddlddldWPEPIKEMQRNWIGRSVGAQVTFKIKDSDKSF  240
            V R+ MRQWMLKITAYA+RLL+DL+++DWPE+IK+MQRNWIG+S GA+VTFK+KD+DK F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  AVFTTRPDTLFGCSYTVLAPENELVKEITSPEQKEAVDAYIKSIESKSDLERTDLNKDKT  300
            +VFTTRPDTLFG +Y+VLAPE+ LV  IT+++Q EAV  Y +    KSDL RTDL K+KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  301  GVFTGAYAINPVNGEEVPVWISDYVLATYGTGAVMAVPAHDERDYAFATKFNLPIKEVVE  360
            GV TG+YAINPVNG E+PVWI+DYVLA+YGTGA+MAVPAHDERD  FA +FNL I  V+E
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  361  GGDISKEAFVGDGVHVNSDFLNGLHNEEAKAKMVDWLTEKGVGEKKVNYKMRDWNFSRQR  420
            GG++   AF  DG+H+NSDFL+GL++  A AKMV+WL   GVG+ +V Y++RDW FSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  421  YWGEPIPVIHWEDGETTLVPEDELPLRLPKESNIKPSGTPESPLANLTDWVNVVDENGRK  480
            YWGEPIP+IHWEDG +T VPE ELPL LP   +I+PSGT ESPLAN+TDW++V  E+G K
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  481  GKRETNTMPQWAGSSWYFLRYIDPHNDKALADPELLKKWMPVDLYIGGAEHATLHLLYAR  540
            G+RETNTMPQWAGSSWY+LRYIDPHN   LAD ELLK+W+PVD+Y+GGAEHA LHLLYAR
Sbjct  484  GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYAR  543

Query  541  FWHKVLYDLGVVPTKEPFQKLYNQGLIL--------------------------------  568
            FWHKVLYDLGVVPTKEPFQKL+NQG+IL                                
Sbjct  544  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEE  603

Query  569  --KNHEKMSKSRGNVVNPDDVIDEYGADSLRTYEMFMGPLNASIDWDDNGPSGVKKFLDR  626
              +   KMSKS  NVVNPDDV+++YGAD+LR YEMFMGPL+ASI W ++G  G +KFLDR
Sbjct  604  LEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR  663

Query  627  VWRTFVNDLDLDPIPSEKITDKNDGKLDKIYNETVKTVTEHFEELRFNTAISQMMVFMNA  686
            V R          I +  IT+ N G LDK+YNETVK+VTE+ ++++FNTAI+Q+MVF+NA
Sbjct  664  VYRL---------ITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNA  714

Query  687  CQKVDKIPREYAEGFVKLMAPVAPHMMEEIWHVF-GHDESVQFAAWPTYDASKLVESTVE  745
             +K DK+  +YA GFV+L+AP APH+ EE+W+ + + +ES+ + +WP+YD SKLVE+ VE
Sbjct  715  ANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVE  774

Query  746  MAVTVNGKKRGNFQI  760
            + V ++GK ++++ +
Sbjct  775  IVVQIKGKVKAKLVV  789

320) ST398NM01_1811 in NC_017673


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  879 bits (3330),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 546/837 (66%), Positives = 674/837 (81%), Gaps = 42/837 (5%)

Query  4    YNHNQIEKKWQDYWDENKTFKTNDNLGQKKFYALDMFPYPSGAGLHVGHPEGYTATDIIS  63
            Y+H  IE KWQ +W +N TFKT  + ++ KFYALDMFPYPSGAGLHVGHPEGYTATDI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYKRMQGYNVLHPMGWDAFGLPAEQYALDTGNDPCEFTKKNIQTFKRQIKELGFSYDWDR  123
            R+KR QG NVLHPMGWDAFGLPAEQYA+DTGNDP EFT  NI  FKRQI+ LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVNTTDPEYYKWTQWIFIQLYNKGLAYVDEVAVNWCPALGTVLSNEEVI-DGVSERGGHP  182
            EVNTTDP+YYKWTQWIF +LY+KGLAY  EV+VNW   LGT ++NEEV+ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VYRKPMKQWVLKITEYadqlladlddldWPESLKDMQRNWIGRSEGAKVSFDVDNAEGKV  242
            V RKPM+QW+LKIT YA++LL DL+++DWPES+KDMQRNWIG+S GA+V+F V +++   
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  243  EVFTTRPDTIYGASFLVLSPEHALVDSITTDEYKDQVKAYQTEASKKSDLERTDLAKDKS  302
             VFTTRPDT++GA++ VL+PEHALVD+ITT +  + V  Y+ +AS KSDL RTDLAK+K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  303  GVFTGAYAINPLSGEKVQIWIADYVLSTYGTGAIMAVPAHDDRDYEFAKKFDLPiievie  362
            GV TG+YAINP++G  + +WIADYVL++YGTGAIMAVPAHD+RD EFAK+F+L II V+E
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  363  ggnveeAAYTGEGKHINSGELDGLENEAAITKAIQLLEQKGAGEKKVNYKLRDWLFSRQR  422
            GGNVEEAA+T +G HINS+ LDGL++ +AI+K ++ LE  G G+ +V Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  423  YWGEPIPVIHWEDGTMTTVpeeelplllpeTDEIKPSGTGESPLANIDSFVNVVDEKTGM  482
            YWGEPIP+IHWEDGT T+VPE ELPL+LP T +I+PSGTGESPLAN+   ++V  E  G+
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED-GV  482

Query  483  KGRRETNTMPQWAGSCWYYLRYIDPKNENMLADPEKLKHWLPVDLYIGGVEHAVLHLLYA  542
            KGRRETNTMPQWAGS WYYLRYIDP N + LAD E LK+WLPVD+Y+GG EHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  543  RFWHKVLYDLGIVPTKEPFQKLFNQGMILG------------------------------  572
            RFWHKVLYDLG+VPTKEPFQKLFNQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  573  ---EGNEKMSKSKGNVINPDDIVQSHGADTLRLYEMFMGPLDAAIAWSEKGLDGSRRFLD  629
               ++  KMSKS  NV+NPDD+V+  GADTLR+YEMFMGPLDA+IAWSE GL+GSR+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  630  RVWRLMVNEDGTLSSKIVTTNNKSLDKVYNQTVKKVTEDFETLGFNTAISQLMVFINECY  689
            RV RL+   +      I   N+ +LDKVYN+TVK VTE+ + + FNTAI+QLMVF+N   
Sbjct  663  RVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  690  KVDEVYKPYIEGFVKMLAPIAPHIGEELWSKL-GHEESITYQPWPTYDEALLVDDEVEIV  748
            K D ++  Y  GFV+++AP+APH+GEELW  L +  ESI+Y PWP+YDE+ LV+++VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  749  VQVNGKLRAKIKIAKDTSKEEMQEIALSNDNVKASIEGKDIMKVIAVPQKLVNIVAK  805
            VQ++GK++AK+ +AKD S+EE+QE+AL+N++V+A I GKDI+KVIAVP+KLVNIV K
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

321) leuS in NC_017338


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  879 bits (3328),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 548/837 (66%), Positives = 674/837 (81%), Gaps = 42/837 (5%)

Query  3    YNHNQIEKKWQDYWDENKTFKTNDNLGQKKFYALDMFPYPSGAGLHVGHPEGYTATDIIS  62
            Y+H  IE KWQ +W +N TFKT  + ++ KFYALDMFPYPSGAGLHVGHPEGYTATDI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRMQGYNVLHPMGWDAFGLPAEQYALDTGNDPREFTKKNIQTFKRQIKELGFSYDWDR  122
            R+KR QG NVLHPMGWDAFGLPAEQYA+DTGNDP EFT  NI  FKRQI+ LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVNTTDPEYYKWTQWIFIQLYNKGLAYVDEVAVNWCPALGTVLSNEEVI-DGVSERGGHP  181
            EVNTTDP+YYKWTQWIF +LY+KGLAY  EV+VNW   LGT ++NEEV+ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VYRKPMKQWVLKITEYadqlladlddldWPESLKDMQRNWIGRSEGAKVSFDVDNTKGKV  241
            V RKPM+QW+LKIT YA++LL DL+++DWPES+KDMQRNWIG+S GA+V+F V +T    
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  EVFTTRPDTIYGASFLVLSPEHALVNSITTDEYKEKVKAYQTEASKKSDLERTDLAKDKS  301
             VFTTRPDT++GA++ VL+PEHALV++ITT +  E V  Y+ +AS KSDL RTDLAK+K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAINPLSGEKVQIWIADYVLSTYGTGAIMAVPAHDDRDYEFAKKFDLPiievie  361
            GV TG+YAINP++G  + +WIADYVL++YGTGAIMAVPAHD+RD EFAK+F+L II V+E
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  ggnveeAAYTGEGKHINSGELDGLENEAAITKAIQLLEQKGVGEKKVNYKLRDWLFSRQR  421
            GGNVEEAA+T +G HINS+ LDGL++ +AI+K ++ LE  GVG+ +V Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPVIHWEDGTMTTVpeeelplllpeTDEIKPSGTGESPLANIDSFVNVVDEKTGM  481
            YWGEPIP+IHWEDGT T+VPE ELPL+LP T +I+PSGTGESPLAN+   ++V  E  G+
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED-GV  482

Query  482  KGRRETNTMPQWAGSCWYYLRYIDPKNENMLADPEKLKHWLPVDLYIGGVEHAVLHLLYA  541
            KGRRETNTMPQWAGS WYYLRYIDP N + LAD E LK+WLPVD+Y+GG EHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKVLYDLGIVPTKEPFQKLFNQGMILG------------------------------  571
            RFWHKVLYDLG+VPTKEPFQKLFNQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---EGNEKMSKSKGNVINPDDIVQSHGADTLRLYEMFMGPLDAAIAWSEKGLDGSRRFLD  628
               ++  KMSKS  NV+NPDD+V+  GADTLR+YEMFMGPLDA+IAWSE GL+GSR+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RVWRLMVNEDGTLSSKIVTTNNKSLDKVYNQTVKKVTEDFETLGFNTAISQLMVFINECY  688
            RV RL+   +      I   N+ +LDKVYN+TVK VTE+ + + FNTAI+QLMVF+N   
Sbjct  663  RVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  689  KVDEVYKPYIEGFVKMLAPIAPHIGEELWSKL-GHEESITYQPWPTYDEALLVDDEVEIV  747
            K D ++  Y  GFV+++AP+APH+GEELW  L +  ESI+Y PWP+YDE+ LV+++VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  748  VQVNGKLRAKIKIAKDTSKEEMQEIALSNDNVKASIEGKDIMKVIAVPQKLVNIVAK  804
            VQ++GK++AK+ +AKD S+EE+QE+AL+N++V+A I GKDI+KVIAVP+KLVNIV K
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

322) leuS in NC_017340


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  878 bits (3327),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 547/837 (66%), Positives = 674/837 (81%), Gaps = 42/837 (5%)

Query  3    YNHNQIEKKWQDYWDENKTFKTNDNLGQKKFYALDMFPYPSGAGLHVGHPEGYTATDIIS  62
            Y+H  IE KWQ +W +N TFKT  + ++ KFYALDMFPYPSGAGLHVGHPEGYTATDI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRMQGYNVLHPMGWDAFGLPAEQYALDTGNDPREFTKKNIQTFKRQIKELGFSYDWDR  122
            R+KR QG NVLHPMGWDAFGLPAEQYA+DTGNDP EFT  NI  FKRQI+ LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVNTTDPEYYKWTQWIFIQLYNKGLAYVDEVAVNWCPALGTVLSNEEVI-DGVSERGGHP  181
            EVNTTDP+YYKWTQWIF +LY+KGLAY  EV+VNW   LGT ++NEEV+ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VYRKPMKQWVLKITEYadqlladlddldWPESLKDMQRNWIGRSEGAKVSFDVDNTEGKV  241
            V RKPM+QW+LKIT YA++LL DL+++DWPES+KDMQRNWIG+S GA+V+F V +T+   
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  EVFTTRPDTIYGASFLVLSPEHALVNSITTDEYKEKVKAYQTEASKKSDLERTDLAKDKS  301
             VFTTRPDT++GA++ VL+PEHALV++ITT +  E V  Y+ +AS KSDL RTDLAK+K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAINPLSGEKVQIWIADYVLSTYGTGAIMAVPAHDDRDYEFAKKFDLPiievie  361
            GV TG+YAINP++G  + +WIADYVL++YGTGAIMAVPAHD+RD EFAK+F+L II V+E
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  ggnveeAAYTGEGKHINSGELDGLENEAAITKAIQLLEQKGAGEKKVNYKLRDWLFSRQR  421
            GGNVEEAA+T +G HINS+ LDGL++ +AI+K ++ LE  G G+ +V Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPVIHWEDGTMTTVpeeelplllpeTDEIKPSGTGESPLANIDSFVNVVDEKTGM  481
            YWGEPIP+IHWEDGT T+VPE ELPL+LP T +I+PSGTGESPLAN+   ++V  E  G+
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED-GV  482

Query  482  KGRRETNTMPQWAGSCWYYLRYIDPKNENMLADPEKLKHWLPVDLYIGGVEHAVLHLLYA  541
            KGRRETNTMPQWAGS WYYLRYIDP N + LAD E LK+WLPVD+Y+GG EHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKVLYDLGIVPTKEPFQKLFNQGMILG------------------------------  571
            RFWHKVLYDLG+VPTKEPFQKLFNQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---EGNEKMSKSKGNVINPDDIVQSHGADTLRLYEMFMGPLDAAIAWSEKGLDGSRRFLD  628
               ++  KMSKS  NV+NPDD+V+  GADTLR+YEMFMGPLDA+IAWSE GL+GSR+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RVWRLMVNEDGTLSSKIVTTNNKSLDKVYNQTVKKVTEDFETLGFNTAISQLMVFINECY  688
            RV RL+   +      I   N+ +LDKVYN+TVK VTE+ + + FNTAI+QLMVF+N   
Sbjct  663  RVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  689  KVDEVYKPYIEGFVKMLAPIAPHIGEELWSKL-GHEESITYQPWPTYDEALLVDDEVEIV  747
            K D ++  Y  GFV+++AP+APH+GEELW  L +  ESI+Y PWP+YDE+ LV+++VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  748  VQVNGKLRAKIKIAKDTSKEEMQEIALSNDNVKASIEGKDIMKVIAVPQKLVNIVAK  804
            VQ++GK++AK+ +AKD S+EE+QE+AL+N++V+A I GKDI+KVIAVP+KLVNIV K
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

323) leuS in NC_018608


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  878 bits (3325),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 546/837 (66%), Positives = 674/837 (81%), Gaps = 42/837 (5%)

Query  4    YNHNQIEKKWQDYWDENKTFKTNDNLGQKKFYALDMFPYPSGAGLHVGHPEGYTATDIIS  63
            Y+H  IE KWQ +W +N TFKT  + ++ KFYALDMFPYPSGAGLHVGHPEGYTATDI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYKRMQGYNVLHPMGWDAFGLPAEQYALDTGNDPREFTKKNIQTFKRQIKELGFSYDWDR  123
            R+KR QG NVLHPMGWDAFGLPAEQYA+DTGNDP EFT  NI  FKRQI+ LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVNTTDPEYYKWTQWIFIQLYNKGLAYVDEVAVNWCPALGTVLSNEEVI-DGVSERGGHP  182
            EVNTTDP+YYKWTQWIF +LY+KGLAY  EV+VNW   LGT ++NEEV+ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VYRKPMKQWVLKITEYadqlladlddldWPESLKDMQRNWIGRSEGAKVSFDVDNAEGKV  242
            V RKPM+QW+LKIT YA++LL DL+++DWPES+KDMQRNWIG+S GA+V+F V +++   
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  243  EVFTTRPDTIYGASFLVLSPEHALVDSITTDEYKDQVKAYQTEASKKSDLERTDLAKDKS  302
             VFTTRPDT++GA++ VL+PEHALVD+ITT +  + V  Y+ +AS KSDL RTDLAK+K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  303  GVFTGAYAINPLSGEKVQIWIADYVLSTYGTGAIMAVPAHDDRDYEFAKKFDLPiievie  362
            GV TG+YAINP++G  + +WIADYVL++YGTGAIMAVPAHD+RD EFAK+F+L II V+E
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  363  ggnveeAAYTGEGKHINSGELDGLENEAAITKAIQLLEQKGAGEKKVNYKLRDWLFSRQR  422
            GGNVEEAA+T +G HINS+ LDGL++ +AI+K ++ LE  G G+ +V Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  423  YWGEPIPVIHWEDGTMTTVpeeelplllpeTDEIKPSGTGESPLANIDSFVNVVDEKTGM  482
            YWGEPIP+IHWEDGT T+VPE ELPL+LP T +I+PSGTGESPLAN+   ++V  E  G+
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED-GV  482

Query  483  KGRRETNTMPQWAGSCWYYLRYIDPKNENMLADPEKLKHWLPVDLYIGGVEHAVLHLLYA  542
            KGRRETNTMPQWAGS WYYLRYIDP N + LAD E LK+WLPVD+Y+GG EHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  543  RFWHKVLYDLGIVPTKEPFQKLFNQGMILG------------------------------  572
            RFWHKVLYDLG+VPTKEPFQKLFNQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  573  ---EGNEKMSKSKGNVINPDDIVQSHGADTLRLYEMFMGPLDAAIAWSEKGLDGSRRFLD  629
               ++  KMSKS  NV+NPDD+V+  GADTLR+YEMFMGPLDA+IAWSE GL+GSR+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  630  RVWRLMVNEDGTLSSKIVTTNNKSLDKVYNQTVKKVTEDFETLGFNTAISQLMVFINECY  689
            RV RL+   +      I   N+ +LDKVYN+TVK VTE+ + + FNTAI+QLMVF+N   
Sbjct  663  RVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  690  KVDEVYKPYIEGFVKMLAPIAPHIGEELWSKL-GHEESITYQPWPTYDEALLVDDEVEIV  748
            K D ++  Y  GFV+++AP+APH+GEELW  L +  ESI+Y PWP+YDE+ LV+++VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  749  VQVNGKLRAKIKIAKDTSKEEMQEIALSNDNVKASIEGKDIMKVIAVPQKLVNIVAK  805
            VQ++GK++AK+ +AKD S+EE+QE+AL+N++V+A I GKDI+KVIAVP+KLVNIV K
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

324) leuS in NC_017351


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  878 bits (3327),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 547/837 (66%), Positives = 674/837 (81%), Gaps = 42/837 (5%)

Query  3    YNHNQIEKKWQDYWDENKTFKTNDNLGQKKFYALDMFPYPSGAGLHVGHPEGYTATDIIS  62
            Y+H  IE KWQ +W +N TFKT  + ++ KFYALDMFPYPSGAGLHVGHPEGYTATDI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRMQGYNVLHPMGWDAFGLPAEQYALDTGNDPREFTKKNIQTFKRQIKELGFSYDWDR  122
            R+KR QG NVLHPMGWDAFGLPAEQYA+DTGNDP EFT  NI  FKRQI+ LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVNTTDPEYYKWTQWIFIQLYNKGLAYVDEVAVNWCPALGTVLSNEEVI-DGVSERGGHP  181
            EVNTTDP+YYKWTQWIF +LY+KGLAY  EV+VNW   LGT ++NEEV+ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VYRKPMKQWVLKITEYadqlladlddldWPESLKDMQRNWIGRSEGAKVSFDVDNTEGKV  241
            V RKPM+QW+LKIT YA++LL DL+++DWPES+KDMQRNWIG+S GA+V+F V +T+   
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  EVFTTRPDTIYGASFLVLSPEHALVNSITTDEYKEKVKAYQTEASKKSDLERTDLAKDKS  301
             VFTTRPDT++GA++ VL+PEHALV++ITT +  E V  Y+ +AS KSDL RTDLAK+K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAINPLSGEKVQIWIADYVLSTYGTGAIMAVPAHDDRDYEFAKKFDLPiievie  361
            GV TG+YAINP++G  + +WIADYVL++YGTGAIMAVPAHD+RD EFAK+F+L II V+E
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  ggnveeAAYTGEGKHINSGELDGLENEAAITKAIQLLEQKGAGEKKVNYKLRDWLFSRQR  421
            GGNVEEAA+T +G HINS+ LDGL++ +AI+K ++ LE  G G+ +V Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPVIHWEDGTMTTVpeeelplllpeTDEIKPSGTGESPLANIDSFVNVVDEKTGM  481
            YWGEPIP+IHWEDGT T+VPE ELPL+LP T +I+PSGTGESPLAN+   ++V  E  G+
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED-GV  482

Query  482  KGRRETNTMPQWAGSCWYYLRYIDPKNENMLADPEKLKHWLPVDLYIGGVEHAVLHLLYA  541
            KGRRETNTMPQWAGS WYYLRYIDP N + LAD E LK+WLPVD+Y+GG EHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKVLYDLGIVPTKEPFQKLFNQGMILG------------------------------  571
            RFWHKVLYDLG+VPTKEPFQKLFNQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---EGNEKMSKSKGNVINPDDIVQSHGADTLRLYEMFMGPLDAAIAWSEKGLDGSRRFLD  628
               ++  KMSKS  NV+NPDD+V+  GADTLR+YEMFMGPLDA+IAWSE GL+GSR+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RVWRLMVNEDGTLSSKIVTTNNKSLDKVYNQTVKKVTEDFETLGFNTAISQLMVFINECY  688
            RV RL+   +      I   N+ +LDKVYN+TVK VTE+ + + FNTAI+QLMVF+N   
Sbjct  663  RVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  689  KVDEVYKPYIEGFVKMLAPIAPHIGEELWSKL-GHEESITYQPWPTYDEALLVDDEVEIV  747
            K D ++  Y  GFV+++AP+APH+GEELW  L +  ESI+Y PWP+YDE+ LV+++VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  748  VQVNGKLRAKIKIAKDTSKEEMQEIALSNDNVKASIEGKDIMKVIAVPQKLVNIVAK  804
            VQ++GK++AK+ +AKD S+EE+QE+AL+N++V+A I GKDI+KVIAVP+KLVNIV K
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

325) SAAG_01660 in NC_022113


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  878 bits (3324),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 546/837 (66%), Positives = 674/837 (81%), Gaps = 42/837 (5%)

Query  4    YNHNQIEKKWQDYWDENKTFKTNDNLGQKKFYALDMFPYPSGAGLHVGHPEGYTATDIIS  63
            Y+H  IE KWQ +W +N TFKT  + ++ KFYALDMFPYPSGAGLHVGHPEGYTATDI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYKRMQGYNVLHPMGWDAFGLPAEQYALDTGNDPREFTKKNIQTFKRQIKELGFSYDWDR  123
            R+KR QG NVLHPMGWDAFGLPAEQYA+DTGNDP EFT  NI  FKRQI+ LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVNTTDPEYYKWTQWIFIQLYNKGLAYVDEVAVNWCPALGTVLSNEEVI-DGVSERGGHP  182
            EVNTTDP+YYKWTQWIF +LY+KGLAY  EV+VNW   LGT ++NEEV+ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VYRKPMKQWVLKITEYadqlladlddldWPESLKDMQRNWIGRSEGAKVSFDVDNSEGKV  242
            V RKPM+QW+LKIT YA++LL DL+++DWPES+KDMQRNWIG+S GA+V+F V +++   
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  243  EVFTTRPDTIYGASFLVLSPEHALVDSITTDEYKDQVKAYQTEASKKSDLERTDLAKDKS  302
             VFTTRPDT++GA++ VL+PEHALVD+ITT +  + V  Y+ +AS KSDL RTDLAK+K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  303  GVFTGAYAINPLSGEKVQIWIADYVLSTYGTGAIMAVPAHDDRDYEFAKKFDLPiievie  362
            GV TG+YAINP++G  + +WIADYVL++YGTGAIMAVPAHD+RD EFAK+F+L II V+E
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  363  ggnveeAAYTGEGKHINSGELDGLENEAAITKAIQLLEKKGAGEKKVNYKLRDWLFSRQR  422
            GGNVEEAA+T +G HINS+ LDGL++ +AI+K ++ LE  G G+ +V Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  423  YWGEPIPVIHWEDGTMTTVpeeelplllpeTDEIKPSGTGESPLANIDSFVNVVDEKTGM  482
            YWGEPIP+IHWEDGT T+VPE ELPL+LP T +I+PSGTGESPLAN+   ++V  E  G+
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED-GV  482

Query  483  KGRRETNTMPQWAGSCWYYLRYIDPKNENMLADPERLKHWLPVDLYIGGVEHAVLHLLYA  542
            KGRRETNTMPQWAGS WYYLRYIDP N + LAD E LK+WLPVD+Y+GG EHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  543  RFWHKVLYDLGIVPTKEPFQKLFNQGMILG------------------------------  572
            RFWHKVLYDLG+VPTKEPFQKLFNQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  573  ---EGNEKMSKSKGNVINPDDIVQSHGADTLRLYEMFMGPLDAAIAWSEKGLDGSRRFLD  629
               ++  KMSKS  NV+NPDD+V+  GADTLR+YEMFMGPLDA+IAWSE GL+GSR+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  630  RVWRLMVNEDGTLSSKIVTTNNKSLDKVYNQTVKKVTEDFETLGFNTAISQLMVFINECY  689
            RV RL+   +      I   N+ +LDKVYN+TVK VTE+ + + FNTAI+QLMVF+N   
Sbjct  663  RVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  690  KVDEVYKPYIEGFVKMLAPIAPHIGEELWSKL-GHEESITYQPWPTYDEALLVDDEVEIV  748
            K D ++  Y  GFV+++AP+APH+GEELW  L +  ESI+Y PWP+YDE+ LV+++VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  749  VQVNGKLRAKIKIAKDTSKEEMQEIALSNDNVKASIEGKDIMKVIAVPQKLVNIVAK  805
            VQ++GK++AK+ +AKD S+EE+QE+AL+N++V+A I GKDI+KVIAVP+KLVNIV K
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

326) leuS in NC_022222


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  878 bits (3324),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 547/837 (66%), Positives = 675/837 (81%), Gaps = 42/837 (5%)

Query  4    YNHNQIEKKWQDYWGENKTFKTNDNLGQKKFYALDMFPYPSGAGLHVGHPEGYTATDIIS  63
            Y+H  IE KWQ +W++N TFKT  + ++ KFYALDMFPYPSGAGLHVGHPEGYTATDI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYKRMQGYNVLHPMGWDAFGLPAEQYALDTGNDPREFTKKNIQTFKRQIKELGFSYDWDR  123
            R+KR QG NVLHPMGWDAFGLPAEQYA+DTGNDP EFT  NI  FKRQI+ LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVNTTDPEYYKWTQWIFIQLYNKGLAYVDEVAVNWCPALGTVLSNEEVI-DGVSERGGHP  182
            EVNTTDP+YYKWTQWIF +LY+KGLAY  EV+VNW   LGT ++NEEV+ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VYRKPMKQWVLKITEYadqlladlddldWPESLKDMQRNWIGRSEGAKVSFDVDNTEGKV  242
            V RKPM+QW+LKIT YA++LL DL+++DWPES+KDMQRNWIG+S GA+V+F V +T+   
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  243  EVFTTRPDTIYGASFLVLSPEHALVNSITTDEYKEKVKAYQTEASKKSDLERTDLAKDKS  302
             VFTTRPDT++GA++ VL+PEHALV++ITT +  E V  Y+ +AS KSDL RTDLAK+K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  303  GVFTGAYAINPLSGEKVQIWIADYVLSTYGTGAIMAVPAHDDRDYEFAKKFDLPiievie  362
            GV TG+YAINP++G  + +WIADYVL++YGTGAIMAVPAHD+RD EFAK+F+L II V+E
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  363  ggnveeAAYTGEGKHINSGELDGLENEAAITKAIQLLEQKGAGEKKVNYKLRDWLFSRQR  422
            GGNVEEAA+T +G HINS+ LDGL++ +AI+K ++ LE  G G+ +V Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  423  YWGEPIPVIHWEDGTMTTVpeeelplllpeTDEIKPSGTGESPLANIDSFVNVVDEKTGM  482
            YWGEPIP+IHWEDGT T+VPE ELPL+LP T +I+PSGTGESPLAN+   ++V  E  G+
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED-GV  482

Query  483  KGRRETNTMPQWAGSCWYYLRYIDPKNENMLADPEKLKHWLPVDLYIGGVEHAVLHLLYA  542
            KGRRETNTMPQWAGS WYYLRYIDP N + LAD E LK+WLPVD+Y+GG EHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  543  RFWHKVLYDLGIVPTKEPFQKLFNQGMILG------------------------------  572
            RFWHKVLYDLG+VPTKEPFQKLFNQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  573  ---EGNEKMSKSKGNVINPDDIVQSHGADTLRLYEMFMGPLDAAIAWSEKGLDGSRRFLD  629
               ++  KMSKS  NV+NPDD+V+  GADTLR+YEMFMGPLDA+IAWSE GL+GSR+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  630  RVWRLMVNEDGTLSSKIVTINNKSLDKVYNQTVKKVTEDFETLGFNTAISQLMVFINECY  689
            RV RL+   +      I   N+ +LDKVYN+TVK VTE+ + + FNTAI+QLMVF+N   
Sbjct  663  RVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  690  KVDEVYKPYIEGFVKMLAPIAPHIGEELWSKL-GHEESITYQPWPTYDEALLVDDEVEIV  748
            K D ++  Y  GFV+++AP+APH+GEELW  L +  ESI+Y PWP+YDE+ LV+++VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  749  VQVNGKLRAKIKIAKDTSKEEMQEIALSNDNVKASIEGKDIMKVIAVPQKLVNIVAK  805
            VQ++GK++AK+ +AKD S+EE+QE+AL+N++V+A I GKDI+KVIAVP+KLVNIV K
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

327) leuS in NC_017343


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  878 bits (3327),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 547/837 (66%), Positives = 674/837 (81%), Gaps = 42/837 (5%)

Query  3    YNHNQIEKKWQDYWDENKTFKTNDNLGQKKFYALDMFPYPSGAGLHVGHPEGYTATDIIS  62
            Y+H  IE KWQ +W +N TFKT  + ++ KFYALDMFPYPSGAGLHVGHPEGYTATDI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRMQGYNVLHPMGWDAFGLPAEQYALDTGNDPREFTKKNIQTFKRQIKELGFSYDWDR  122
            R+KR QG NVLHPMGWDAFGLPAEQYA+DTGNDP EFT  NI  FKRQI+ LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVNTTDPEYYKWTQWIFIQLYNKGLAYVDEVAVNWCPALGTVLSNEEVI-DGVSERGGHP  181
            EVNTTDP+YYKWTQWIF +LY+KGLAY  EV+VNW   LGT ++NEEV+ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VYRKPMKQWVLKITEYadqlladlddldWPESLKDMQRNWIGRSEGAKVSFDVDNTEGKV  241
            V RKPM+QW+LKIT YA++LL DL+++DWPES+KDMQRNWIG+S GA+V+F V +T+   
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  EVFTTRPDTIYGASFLVLSPEHALVNSITTDEYKEKVKAYQTEASKKSDLERTDLAKDKS  301
             VFTTRPDT++GA++ VL+PEHALV++ITT +  E V  Y+ +AS KSDL RTDLAK+K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAINPLSGEKVQIWIADYVLSTYGTGAIMAVPAHDDRDYEFAKKFDLPiievie  361
            GV TG+YAINP++G  + +WIADYVL++YGTGAIMAVPAHD+RD EFAK+F+L II V+E
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  ggnveeAAYTGEGKHINSGELDGLENEAAITKAIQLLEQKGAGEKKVNYKLRDWLFSRQR  421
            GGNVEEAA+T +G HINS+ LDGL++ +AI+K ++ LE  G G+ +V Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPVIHWEDGTMTTVpeeelplllpeTDEIKPSGTGESPLANIDSFVNVVDEKTGM  481
            YWGEPIP+IHWEDGT T+VPE ELPL+LP T +I+PSGTGESPLAN+   ++V  E  G+
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED-GV  482

Query  482  KGRRETNTMPQWAGSCWYYLRYIDPKNENMLADPEKLKHWLPVDLYIGGVEHAVLHLLYA  541
            KGRRETNTMPQWAGS WYYLRYIDP N + LAD E LK+WLPVD+Y+GG EHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKVLYDLGIVPTKEPFQKLFNQGMILG------------------------------  571
            RFWHKVLYDLG+VPTKEPFQKLFNQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---EGNEKMSKSKGNVINPDDIVQSHGADTLRLYEMFMGPLDAAIAWSEKGLDGSRRFLD  628
               ++  KMSKS  NV+NPDD+V+  GADTLR+YEMFMGPLDA+IAWSE GL+GSR+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RVWRLMVNEDGTLSSKIVTTNNKSLDKVYNQTVKKVTEDFETLGFNTAISQLMVFINECY  688
            RV RL+   +      I   N+ +LDKVYN+TVK VTE+ + + FNTAI+QLMVF+N   
Sbjct  663  RVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  689  KVDEVYKPYIEGFVKMLAPIAPHIGEELWSKL-GHEESITYQPWPTYDEALLVDDEVEIV  747
            K D ++  Y  GFV+++AP+APH+GEELW  L +  ESI+Y PWP+YDE+ LV+++VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  748  VQVNGKLRAKIKIAKDTSKEEMQEIALSNDNVKASIEGKDIMKVIAVPQKLVNIVAK  804
            VQ++GK++AK+ +AKD S+EE+QE+AL+N++V+A I GKDI+KVIAVP+KLVNIV K
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

328) SAOV_1744 in NC_017337


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  878 bits (3327),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 546/837 (66%), Positives = 674/837 (81%), Gaps = 42/837 (5%)

Query  4    YNHNQIEKKWQDYWDENKTFKTNDNLGQKKFYALDMFPYPSGAGLHVGHPEGYTATDIIS  63
            Y+H  IE KWQ +W +N TFKT  + ++ KFYALDMFPYPSGAGLHVGHPEGYTATDI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYKRMQGYNVLHPMGWDAFGLPAEQYALDTGNDPREFTKKNIQTFKRQIKELGFSYDWDR  123
            R+KR QG NVLHPMGWDAFGLPAEQYA+DTGNDP EFT  NI  FKRQI+ LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVNTTDPEYYKWTQWIFIQLYNKGLAYVDEVAVNWCPALGTVLSNEEVI-DGVSERGGHP  182
            EVNTTDP+YYKWTQWIF +LY+KGLAY  EV+VNW   LGT ++NEEV+ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VYRKPMKQWVLKITEYadqlladlddldWPESLKDMQRNWIGRSEGAKVAFDVDNAEGKV  242
            V RKPM+QW+LKIT YA++LL DL+++DWPES+KDMQRNWIG+S GA+V+F V +++   
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  243  EVFTTRPDTIYGASFLVLSPEHALVNSITTDEYKEKVKAYQTEASKKSDLERTDLAKDKS  302
             VFTTRPDT++GA++ VL+PEHALV++ITT +  E V  Y+ +AS KSDL RTDLAK+K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  303  GVFTGAYAINPLSGEKVQIWIADYVLSTYGTGAIMAVPAHDDRDFEFAKKFDLPiievie  362
            GV TG+YAINP++G  + +WIADYVL++YGTGAIMAVPAHD+RD EFAK+F+L II V+E
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  363  ggnveeAAYTGEGKHINSGELDGLENEAAITKAIQLLDQKGAGEKKVNYKLRDWLFSRQR  422
            GGNVEEAA+T +G HINS+ LDGL++ +AI+K ++ L+  G G+ +V Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  423  YWGEPIPVIHWEDGTMTTVpeeelplllpeTDEIKPSGTGESPLANIDSFVNVIDEKTGM  482
            YWGEPIP+IHWEDGT T+VPE ELPL+LP T +I+PSGTGESPLAN+   ++V  E  G+
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED-GV  482

Query  483  KGRRETNTMPQWAGSCWYYLRYIDPKNENMLADPEKLKHWLPVDLYIGGVEHAVLHLLYA  542
            KGRRETNTMPQWAGS WYYLRYIDP N + LAD E LK+WLPVD+Y+GG EHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  543  RFWHKVLYDLGIVPTKEPFQKLFNQGMILG------------------------------  572
            RFWHKVLYDLG+VPTKEPFQKLFNQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  573  ---EGNEKMSKSKGNVINPDDIVQSHGADTLRLYEMFMGPLDAAIAWSEKGLDGSRRFLD  629
               ++  KMSKS  NV+NPDD+V+  GADTLR+YEMFMGPLDA+IAWSE GL+GSR+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  630  RVWRLIVNEDGTLSSKIVTTNNKSLDKVYNQTVKKVTEDFETLGFNTAISQLMVFINECY  689
            RV RLI   +      I   N+ +LDKVYN+TVK VTE+ + + FNTAI+QLMVF+N   
Sbjct  663  RVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  690  KVDEVYKPYIEGFVKMLAPIAPHIGEELWSKL-GHEESITYQPWPTYDEALLVDDEVEIV  748
            K D ++  Y  GFV+++AP+APH+GEELW  L +  ESI+Y PWP+YDE+ LV+++VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  749  VQVNGKLRAKIKIAKDTSKEEMQEIALSNDNVKASIEGKDIMKVIAVPQKLVNIVAK  805
            VQ++GK++AK+ +AKD S+EE+QE+AL+N++V+A I GKDI+KVIAVP+KLVNIV K
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

329) leuS in NC_013450


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  878 bits (3326),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 547/837 (66%), Positives = 674/837 (81%), Gaps = 42/837 (5%)

Query  4    YNHNQIEKKWQDYWDENKTFKTNDNLGQKKFYALDMFPYPSGAGLHVGHPEGYTATDIIS  63
            Y+H  IE KWQ +W +N TFKT  + ++ KFYALDMFPYPSGAGLHVGHPEGYTATDI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYKRMQGYNVLHPMGWDAFGLPAEQYALDTGNDPREFTKKNIQTFKRQIKELGFSYDWDR  123
            R+KR QG NVLHPMGWDAFGLPAEQYA+DTGNDP EFT  NI  FKRQI+ LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVNTTDPEYYKWTQWIFIQLYNKGLAYVDEVAVNWCPALGTVLSNEEVI-DGVSERGGHP  182
            EVNTTDP+YYKWTQWIF +LY+KGLAY  EV+VNW   LGT ++NEEV+ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VYRKPMKQWVLKITEYadqlladlddldWPESLKDMQRNWIGRSEGAKVSFDVDNTEGKV  242
            V RKPM+QW+LKIT YA++LL DL+++DWPES+KDMQRNWIG+S GA+V+F V +T+   
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  243  EVFTTRPDTIYGASFLVLSPEHALVNSITTDEYKEKVKAYQTEASKKSDLERTDLAKDKS  302
             VFTTRPDT++GA++ VL+PEHALV++ITT +  E V  Y+ +AS KSDL RTDLAK+K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  303  GVFTGAYAINPLSGEKVQIWIADYVLSTYGTGAIMAVPAHDDRDYEFAKKFDLPiievie  362
            GV TG+YAINP++G  + +WIADYVL++YGTGAIMAVPAHD+RD EFAK+F+L II V+E
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  363  ggnveeAAYTGEGKHINSGELDGLENEAAITKAIQLLEQKGAGEKKVNYKLRDWLFSRQR  422
            GGNVEEAA+T +G HINS+ LDGL++ +AI+K ++ LE  G G+ +V Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  423  YWGEPIPVIHWEDGTMTTVpeeelplllpeTDEIKPSGTGESPLANIDSFVNVVDEKTGM  482
            YWGEPIP+IHWEDGT T+VPE ELPL+LP T +I+PSGTGESPLAN+   ++V  E  G+
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED-GV  482

Query  483  KGRRETNTMPQWAGSCWYYLRYIDPKNENMLADPEKLKHWLPVDLYIGGVEHAVLHLLYA  542
            KGRRETNTMPQWAGS WYYLRYIDP N + LAD E LK+WLPVD+Y+GG EHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  543  RFWHKVLYDLGIVPTKEPFQKLFNQGMILG------------------------------  572
            RFWHKVLYDLG+VPTKEPFQKLFNQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  573  ---EGNEKMSKSKGNVINPDDIVQSHGADTLRLYEMFMGPLDAAIAWSEKGLDGSRRFLD  629
               ++  KMSKS  NV+NPDD+V+  GADTLR+YEMFMGPLDA+IAWSE GL+GSR+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  630  RVWRLMVNEDGTLSSKIVTTNNKSLDKVYNQTVKKVTEDFETLGFNTAISQLMVFINECY  689
            RV RL+   +      I   N+ +LDKVYN+TVK VTE+ + + FNTAI+QLMVF+N   
Sbjct  663  RVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  690  KVDEVYKPYIEGFVKMLAPIAPHIGEELWSKL-GHEESITYQPWPTYDEALLVDDEVEIV  748
            K D ++  Y  GFV+++AP+APH+GEELW  L +  ESI+Y PWP+YDE+ LV+++VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  749  VQVNGKLRAKIKIAKDTSKEEMQEIALSNDNVKASIEGKDIMKVIAVPQKLVNIVAK  805
            VQ++GK++AK+ +AKD S+EE+QE+AL+N++V+A I GKDI+KVIAVP+KLVNIV K
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

330) leuS in NC_009632


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  878 bits (3326),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 547/837 (66%), Positives = 674/837 (81%), Gaps = 42/837 (5%)

Query  4    YNHNQIEKKWQDYWDENKTFKTNDNLGQKKFYALDMFPYPSGAGLHVGHPEGYTATDIIS  63
            Y+H  IE KWQ +W +N TFKT  + ++ KFYALDMFPYPSGAGLHVGHPEGYTATDI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYKRMQGYNVLHPMGWDAFGLPAEQYALDTGNDPREFTKKNIQTFKRQIKELGFSYDWDR  123
            R+KR QG NVLHPMGWDAFGLPAEQYA+DTGNDP EFT  NI  FKRQI+ LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVNTTDPEYYKWTQWIFIQLYNKGLAYVDEVAVNWCPALGTVLSNEEVI-DGVSERGGHP  182
            EVNTTDP+YYKWTQWIF +LY+KGLAY  EV+VNW   LGT ++NEEV+ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VYRKPMKQWVLKITEYadqlladlddldWPESLKDMQRNWIGRSEGAKVSFDVDNTEGKV  242
            V RKPM+QW+LKIT YA++LL DL+++DWPES+KDMQRNWIG+S GA+V+F V +T+   
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  243  EVFTTRPDTIYGASFLVLSPEHALVNSITTDEYKEKVKAYQTEASKKSDLERTDLAKDKS  302
             VFTTRPDT++GA++ VL+PEHALV++ITT +  E V  Y+ +AS KSDL RTDLAK+K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  303  GVFTGAYAINPLSGEKVQIWIADYVLSTYGTGAIMAVPAHDDRDYEFAKKFDLPiievie  362
            GV TG+YAINP++G  + +WIADYVL++YGTGAIMAVPAHD+RD EFAK+F+L II V+E
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  363  ggnveeAAYTGEGKHINSGELDGLENEAAITKAIQLLEQKGAGEKKVNYKLRDWLFSRQR  422
            GGNVEEAA+T +G HINS+ LDGL++ +AI+K ++ LE  G G+ +V Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  423  YWGEPIPVIHWEDGTMTTVpeeelplllpeTDEIKPSGTGESPLANIDSFVNVVDEKTGM  482
            YWGEPIP+IHWEDGT T+VPE ELPL+LP T +I+PSGTGESPLAN+   ++V  E  G+
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED-GV  482

Query  483  KGRRETNTMPQWAGSCWYYLRYIDPKNENMLADPEKLKHWLPVDLYIGGVEHAVLHLLYA  542
            KGRRETNTMPQWAGS WYYLRYIDP N + LAD E LK+WLPVD+Y+GG EHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  543  RFWHKVLYDLGIVPTKEPFQKLFNQGMILG------------------------------  572
            RFWHKVLYDLG+VPTKEPFQKLFNQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  573  ---EGNEKMSKSKGNVINPDDIVQSHGADTLRLYEMFMGPLDAAIAWSEKGLDGSRRFLD  629
               ++  KMSKS  NV+NPDD+V+  GADTLR+YEMFMGPLDA+IAWSE GL+GSR+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  630  RVWRLMVNEDGTLSSKIVTTNNKSLDKVYNQTVKKVTEDFETLGFNTAISQLMVFINECY  689
            RV RL+   +      I   N+ +LDKVYN+TVK VTE+ + + FNTAI+QLMVF+N   
Sbjct  663  RVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  690  KVDEVYKPYIEGFVKMLAPIAPHIGEELWSKL-GHEESITYQPWPTYDEALLVDDEVEIV  748
            K D ++  Y  GFV+++AP+APH+GEELW  L +  ESI+Y PWP+YDE+ LV+++VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  749  VQVNGKLRAKIKIAKDTSKEEMQEIALSNDNVKASIEGKDIMKVIAVPQKLVNIVAK  805
            VQ++GK++AK+ +AKD S+EE+QE+AL+N++V+A I GKDI+KVIAVP+KLVNIV K
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

331) leuS in NC_009487


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  878 bits (3326),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 547/837 (66%), Positives = 674/837 (81%), Gaps = 42/837 (5%)

Query  4    YNHNQIEKKWQDYWDENKTFKTNDNLGQKKFYALDMFPYPSGAGLHVGHPEGYTATDIIS  63
            Y+H  IE KWQ +W +N TFKT  + ++ KFYALDMFPYPSGAGLHVGHPEGYTATDI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYKRMQGYNVLHPMGWDAFGLPAEQYALDTGNDPREFTKKNIQTFKRQIKELGFSYDWDR  123
            R+KR QG NVLHPMGWDAFGLPAEQYA+DTGNDP EFT  NI  FKRQI+ LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVNTTDPEYYKWTQWIFIQLYNKGLAYVDEVAVNWCPALGTVLSNEEVI-DGVSERGGHP  182
            EVNTTDP+YYKWTQWIF +LY+KGLAY  EV+VNW   LGT ++NEEV+ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VYRKPMKQWVLKITEYadqlladlddldWPESLKDMQRNWIGRSEGAKVSFDVDNTEGKV  242
            V RKPM+QW+LKIT YA++LL DL+++DWPES+KDMQRNWIG+S GA+V+F V +T+   
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  243  EVFTTRPDTIYGASFLVLSPEHALVNSITTDEYKEKVKAYQTEASKKSDLERTDLAKDKS  302
             VFTTRPDT++GA++ VL+PEHALV++ITT +  E V  Y+ +AS KSDL RTDLAK+K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  303  GVFTGAYAINPLSGEKVQIWIADYVLSTYGTGAIMAVPAHDDRDYEFAKKFDLPiievie  362
            GV TG+YAINP++G  + +WIADYVL++YGTGAIMAVPAHD+RD EFAK+F+L II V+E
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  363  ggnveeAAYTGEGKHINSGELDGLENEAAITKAIQLLEQKGAGEKKVNYKLRDWLFSRQR  422
            GGNVEEAA+T +G HINS+ LDGL++ +AI+K ++ LE  G G+ +V Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  423  YWGEPIPVIHWEDGTMTTVpeeelplllpeTDEIKPSGTGESPLANIDSFVNVVDEKTGM  482
            YWGEPIP+IHWEDGT T+VPE ELPL+LP T +I+PSGTGESPLAN+   ++V  E  G+
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED-GV  482

Query  483  KGRRETNTMPQWAGSCWYYLRYIDPKNENMLADPEKLKHWLPVDLYIGGVEHAVLHLLYA  542
            KGRRETNTMPQWAGS WYYLRYIDP N + LAD E LK+WLPVD+Y+GG EHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  543  RFWHKVLYDLGIVPTKEPFQKLFNQGMILG------------------------------  572
            RFWHKVLYDLG+VPTKEPFQKLFNQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  573  ---EGNEKMSKSKGNVINPDDIVQSHGADTLRLYEMFMGPLDAAIAWSEKGLDGSRRFLD  629
               ++  KMSKS  NV+NPDD+V+  GADTLR+YEMFMGPLDA+IAWSE GL+GSR+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  630  RVWRLMVNEDGTLSSKIVTTNNKSLDKVYNQTVKKVTEDFETLGFNTAISQLMVFINECY  689
            RV RL+   +      I   N+ +LDKVYN+TVK VTE+ + + FNTAI+QLMVF+N   
Sbjct  663  RVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  690  KVDEVYKPYIEGFVKMLAPIAPHIGEELWSKL-GHEESITYQPWPTYDEALLVDDEVEIV  748
            K D ++  Y  GFV+++AP+APH+GEELW  L +  ESI+Y PWP+YDE+ LV+++VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  749  VQVNGKLRAKIKIAKDTSKEEMQEIALSNDNVKASIEGKDIMKVIAVPQKLVNIVAK  805
            VQ++GK++AK+ +AKD S+EE+QE+AL+N++V+A I GKDI+KVIAVP+KLVNIV K
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

332) leuS in NC_017349


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  878 bits (3324),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 546/837 (66%), Positives = 674/837 (81%), Gaps = 42/837 (5%)

Query  4    YNHNQIEKKWQDYWDENKTFKTNDNLGQKKFYALDMFPYPSGAGLHVGHPEGYTATDIIS  63
            Y+H  IE KWQ +W +N TFKT  + ++ KFYALDMFPYPSGAGLHVGHPEGYTATDI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYKRMQGYNVLHPMGWDAFGLPAEQYALDTGNDPREFTKKNIQTFKRQIKELGFSYDWDR  123
            R+KR QG NVLHPMGWDAFGLPAEQYA+DTGNDP EFT  NI  FKRQI+ LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVNTTDPEYYKWTQWIFIQLYNKGLAYVDEVAVNWCPALGTVLSNEEVI-DGVSERGGHP  182
            EVNTTDP+YYKWTQWIF +LY+KGLAY  EV+VNW   LGT ++NEEV+ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VYRKPMKQWVLKITEYadqlladlddldWPESLKDMQRNWIGRSEGAKVSFDVDNAEGKV  242
            V RKPM+QW+LKIT YA++LL DL+++DWPES+KDMQRNWIG+S GA+V+F V +++   
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  243  EVFTTRPDTIYGASFLVLSPEHALVNSITTDEYKEKVKAYQTEASKKSDLERTDLAKDKS  302
             VFTTRPDT++GA++ VL+PEHALV++ITT +  E V  Y+ +AS KSDL RTDLAK+K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  303  GVFTGAYAINPLSGEKVQIWIADYVLSTYGTGAIMAVPAHDDRDFEFAKKFDLPiievie  362
            GV TG+YAINP++G  + +WIADYVL++YGTGAIMAVPAHD+RD EFAK+F+L II V+E
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  363  ggnveeAAYTGEGKHINSGELDGLENEAAITKAIQLLEQKGAGEKKVNYKLRDWLFSRQR  422
            GGNVEEAA+T +G HINS+ LDGL++ +AI+K ++ LE  G G+ +V Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  423  YWGEPIPVIHWEDGTMTTVpeeelplllpeTDEIKPSGTGESPLANIDSFVNVVDEKTGM  482
            YWGEPIP+IHWEDGT T+VPE ELPL+LP T +I+PSGTGESPLAN+   ++V  E  G+
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED-GV  482

Query  483  KGRRETNTMPQWAGSCWYYLRYIDPKNENMLADPEKLKHWLPVDLYIGGVEHAVLHLLYA  542
            KGRRETNTMPQWAGS WYYLRYIDP N + LAD E LK+WLPVD+Y+GG EHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  543  RFWHKVLYDLGIVPTKEPFQKLFNQGMILG------------------------------  572
            RFWHKVLYDLG+VPTKEPFQKLFNQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  573  ---EGNEKMSKSKGNVINPDDIVQSHGADTLRLYEMFMGPLDAAIAWSEKGLDGSRRFLD  629
               ++  KMSKS  NV+NPDD+V+  GADTLR+YEMFMGPLDA+IAWSE GL+GSR+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  630  RVWRLMVNEDGTLSSKIVTTNNKSLDKVYNQTVKKVTEDFETLGFNTAISQLMVFINECY  689
            RV RL+   +      I   N+ +LDKVYN+TVK VTE+ + + FNTAI+QLMVF+N   
Sbjct  663  RVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  690  KVDEVYKPYIEGFVKMLAPIAPHIGEELWSKL-GHEESITYQPWPTYDEALLVDDEVEIV  748
            K D ++  Y  GFV+++AP+APH+GEELW  L +  ESI+Y PWP+YDE+ LV+++VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  749  VQVNGKLRAKIKIAKDTSKEEMQEIALSNDNVKASIEGKDIMKVIAVPQKLVNIVAK  805
            VQ++GK++AK+ +AKD S+EE+QE+AL+N++V+A I GKDI+KVIAVP+KLVNIV K
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

333) M013TW_1774 in NC_016928


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  878 bits (3326),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 547/837 (66%), Positives = 674/837 (81%), Gaps = 42/837 (5%)

Query  4    YNHNQIEKKWQDYWDENKTFKTNDNLGQKKFYALDMFPYPSGAGLHVGHPEGYTATDIIS  63
            Y+H  IE KWQ +W +N TFKT  + ++ KFYALDMFPYPSGAGLHVGHPEGYTATDI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYKRMQGYNVLHPMGWDAFGLPAEQYALDTGNDPREFTKKNIQTFKRQIKELGFSYDWDR  123
            R+KR QG NVLHPMGWDAFGLPAEQYA+DTGNDP EFT  NI  FKRQI+ LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVNTTDPEYYKWTQWIFIQLYNKGLAYVDEVAVNWCPALGTVLSNEEVI-DGVSERGGHP  182
            EVNTTDP+YYKWTQWIF +LY+KGLAY  EV+VNW   LGT ++NEEV+ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VYRKPMKQWVLKITEYadqlladlddldWPESLKDMQRNWIGRSEGAKVSFDVDNTEGKV  242
            V RKPM+QW+LKIT YA++LL DL+++DWPES+KDMQRNWIG+S GA+V+F V +T+   
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  243  EVFTTRPDTIYGASFLVLSPEHALVNSITTDEYKEKVKAYQTEASKKSDLERTDLAKDKS  302
             VFTTRPDT++GA++ VL+PEHALV++ITT +  E V  Y+ +AS KSDL RTDLAK+K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  303  GVFTGAYAINPLSGEKVQIWIADYVLSTYGTGAIMAVPAHDDRDYEFAKKFDLPiievie  362
            GV TG+YAINP++G  + +WIADYVL++YGTGAIMAVPAHD+RD EFAK+F+L II V+E
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  363  ggnveeAAYTGEGKHINSGELDGLENEAAITKAIQLLEQKGAGEKKVNYKLRDWLFSRQR  422
            GGNVEEAA+T +G HINS+ LDGL++ +AI+K ++ LE  G G+ +V Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  423  YWGEPIPVIHWEDGTMTTVpeeelplllpeTDEIKPSGTGESPLANIDSFVNVVDEKTGM  482
            YWGEPIP+IHWEDGT T+VPE ELPL+LP T +I+PSGTGESPLAN+   ++V  E  G+
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED-GV  482

Query  483  KGRRETNTMPQWAGSCWYYLRYIDPKNENMLADPEKLKHWLPVDLYIGGVEHAVLHLLYA  542
            KGRRETNTMPQWAGS WYYLRYIDP N + LAD E LK+WLPVD+Y+GG EHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  543  RFWHKVLYDLGIVPTKEPFQKLFNQGMILG------------------------------  572
            RFWHKVLYDLG+VPTKEPFQKLFNQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  573  ---EGNEKMSKSKGNVINPDDIVQSHGADTLRLYEMFMGPLDAAIAWSEKGLDGSRRFLD  629
               ++  KMSKS  NV+NPDD+V+  GADTLR+YEMFMGPLDA+IAWSE GL+GSR+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  630  RVWRLMVNEDGTLSSKIVTTNNKSLDKVYNQTVKKVTEDFETLGFNTAISQLMVFINECY  689
            RV RL+   +      I   N+ +LDKVYN+TVK VTE+ + + FNTAI+QLMVF+N   
Sbjct  663  RVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  690  KVDEVYKPYIEGFVKMLAPIAPHIGEELWSKL-GHEESITYQPWPTYDEALLVDDEVEIV  748
            K D ++  Y  GFV+++AP+APH+GEELW  L +  ESI+Y PWP+YDE+ LV+++VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  749  VQVNGKLRAKIKIAKDTSKEEMQEIALSNDNVKASIEGKDIMKVIAVPQKLVNIVAK  805
            VQ++GK++AK+ +AKD S+EE+QE+AL+N++V+A I GKDI+KVIAVP+KLVNIV K
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

334) leuS in NC_002952


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  878 bits (3326),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 546/837 (66%), Positives = 674/837 (81%), Gaps = 42/837 (5%)

Query  3    YNHNQIEKKWQDYWDENKTFKTNDNLGQKKFYALDMFPYPSGAGLHVGHPEGYTATDIIS  62
            Y+H  IE KWQ +W +N TFKT  + ++ KFYALDMFPYPSGAGLHVGHPEGYTATDI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRMQGYNVLHPMGWDAFGLPAEQYALDTGNDPREFTKKNIQTFKRQIKELGFSYDWDR  122
            R+KR QG NVLHPMGWDAFGLPAEQYA+DTGNDP EFT  NI  FKRQI+ LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVNTTDPEYYKWTQWIFIQLYNKGLAYVDEVAVNWCPALGTVLSNEEVI-DGVSERGGHP  181
            EVNTTDP+YYKWTQWIF +LY+KGLAY  EV+VNW   LGT ++NEEV+ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VYRKPMKQWVLKITEYadqlladlddldWPESLKDMQRNWIGRSEGAKVSFDVDNSEGKV  241
            V RKPM+QW+LKIT YA++LL DL+++DWPES+KDMQRNWIG+S GA+V+F V +++   
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  EVFTTRPDTIYGASFLVLSPEHALVDSITTDEYKDQVKAYQTEASKKSDLERTDLAKDKS  301
             VFTTRPDT++GA++ VL+PEHALVD+ITT +  + V  Y+ +AS KSDL RTDLAK+K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAINPLSGEKVQIWIADYVLSTYGTGAIMAVPAHDDRDYEFAKKFDLPiievie  361
            GV TG+YAINP++G  + +WIADYVL++YGTGAIMAVPAHD+RD EFAK+F+L II V+E
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  ggnveeAAYTGEGKHINSGELDGLENEAAITKAIQLLEKKGAGEKKVNYKLRDWLFSRQR  421
            GGNVEEAA+T +G HINS+ LDGL++ +AI+K ++ LE  G G+ +V Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPVIHWEDGTMTTVpeeelplllpeTDEIKPSGTGESPLANIDSFVNVVDEKTGM  481
            YWGEPIP+IHWEDGT T+VPE ELPL+LP T +I+PSGTGESPLAN+   ++V  E  G+
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED-GV  482

Query  482  KGRRETNTMPQWAGSCWYYLRYIDPKNENMLADPEKLKHWLPVDLYIGGVEHAVLHLLYA  541
            KGRRETNTMPQWAGS WYYLRYIDP N + LAD E LK+WLPVD+Y+GG EHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKVLYDLGIVPTKEPFQKLFNQGMILG------------------------------  571
            RFWHKVLYDLG+VPTKEPFQKLFNQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---EGNEKMSKSKGNVINPDDIVQSHGADTLRLYEMFMGPLDAAIAWSEKGLDGSRRFLD  628
               ++  KMSKS  NV+NPDD+V+  GADTLR+YEMFMGPLDA+IAWSE GL+GSR+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RVWRLMVNEDGTLSSKIVTTNNKSLDKVYNQTVKKVTEDFETLGFNTAISQLMVFINECY  688
            RV RL+   +      I   N+ +LDKVYN+TVK VTE+ + + FNTAI+QLMVF+N   
Sbjct  663  RVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  689  KVDEVYKPYIEGFVKMLAPIAPHIGEELWSKL-GHEESITYQPWPTYDEALLVDDEVEIV  747
            K D ++  Y  GFV+++AP+APH+GEELW  L +  ESI+Y PWP+YDE+ LV+++VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  748  VQVNGKLRAKIKIAKDTSKEEMQEIALSNDNVKASIEGKDIMKVIAVPQKLVNIVAK  804
            VQ++GK++AK+ +AKD S+EE+QE+AL+N++V+A I GKDI+KVIAVP+KLVNIV K
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

335) leuS in NC_009782


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  878 bits (3327),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 547/837 (66%), Positives = 674/837 (81%), Gaps = 42/837 (5%)

Query  3    YNHNQIEKKWQDYWDENKTFKTNDNLGQKKFYALDMFPYPSGAGLHVGHPEGYTATDIIS  62
            Y+H  IE KWQ +W +N TFKT  + ++ KFYALDMFPYPSGAGLHVGHPEGYTATDI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRMQGYNVLHPMGWDAFGLPAEQYALDTGNDPREFTKKNIQTFKRQIKELGFSYDWDR  122
            R+KR QG NVLHPMGWDAFGLPAEQYA+DTGNDP EFT  NI  FKRQI+ LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVNTTDPEYYKWTQWIFIQLYNKGLAYVDEVAVNWCPALGTVLSNEEVI-DGVSERGGHP  181
            EVNTTDP+YYKWTQWIF +LY+KGLAY  EV+VNW   LGT ++NEEV+ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VYRKPMKQWVLKITEYadqlladlddldWPESLKDMQRNWIGRSEGAKVSFDVDNTEGKV  241
            V RKPM+QW+LKIT YA++LL DL+++DWPES+KDMQRNWIG+S GA+V+F V +T+   
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  EVFTTRPDTIYGASFLVLSPEHALVNSITTDEYKEKVKAYQTEASKKSDLERTDLAKDKS  301
             VFTTRPDT++GA++ VL+PEHALV++ITT +  E V  Y+ +AS KSDL RTDLAK+K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAINPLSGEKVQIWIADYVLSTYGTGAIMAVPAHDDRDYEFAKKFDLPiievie  361
            GV TG+YAINP++G  + +WIADYVL++YGTGAIMAVPAHD+RD EFAK+F+L II V+E
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  ggnveeAAYTGEGKHINSGELDGLENEAAITKAIQLLEQKGAGEKKVNYKLRDWLFSRQR  421
            GGNVEEAA+T +G HINS+ LDGL++ +AI+K ++ LE  G G+ +V Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPVIHWEDGTMTTVpeeelplllpeTDEIKPSGTGESPLANIDSFVNVVDEKTGM  481
            YWGEPIP+IHWEDGT T+VPE ELPL+LP T +I+PSGTGESPLAN+   ++V  E  G+
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED-GV  482

Query  482  KGRRETNTMPQWAGSCWYYLRYIDPKNENMLADPEKLKHWLPVDLYIGGVEHAVLHLLYA  541
            KGRRETNTMPQWAGS WYYLRYIDP N + LAD E LK+WLPVD+Y+GG EHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKVLYDLGIVPTKEPFQKLFNQGMILG------------------------------  571
            RFWHKVLYDLG+VPTKEPFQKLFNQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---EGNEKMSKSKGNVINPDDIVQSHGADTLRLYEMFMGPLDAAIAWSEKGLDGSRRFLD  628
               ++  KMSKS  NV+NPDD+V+  GADTLR+YEMFMGPLDA+IAWSE GL+GSR+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RVWRLMVNEDGTLSSKIVTTNNKSLDKVYNQTVKKVTEDFETLGFNTAISQLMVFINECY  688
            RV RL+   +      I   N+ +LDKVYN+TVK VTE+ + + FNTAI+QLMVF+N   
Sbjct  663  RVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  689  KVDEVYKPYIEGFVKMLAPIAPHIGEELWSKL-GHEESITYQPWPTYDEALLVDDEVEIV  747
            K D ++  Y  GFV+++AP+APH+GEELW  L +  ESI+Y PWP+YDE+ LV+++VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  748  VQVNGKLRAKIKIAKDTSKEEMQEIALSNDNVKASIEGKDIMKVIAVPQKLVNIVAK  804
            VQ++GK++AK+ +AKD S+EE+QE+AL+N++V+A I GKDI+KVIAVP+KLVNIV K
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

336) leuS in NC_002758


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  878 bits (3327),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 547/837 (66%), Positives = 674/837 (81%), Gaps = 42/837 (5%)

Query  3    YNHNQIEKKWQDYWDENKTFKTNDNLGQKKFYALDMFPYPSGAGLHVGHPEGYTATDIIS  62
            Y+H  IE KWQ +W +N TFKT  + ++ KFYALDMFPYPSGAGLHVGHPEGYTATDI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRMQGYNVLHPMGWDAFGLPAEQYALDTGNDPREFTKKNIQTFKRQIKELGFSYDWDR  122
            R+KR QG NVLHPMGWDAFGLPAEQYA+DTGNDP EFT  NI  FKRQI+ LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVNTTDPEYYKWTQWIFIQLYNKGLAYVDEVAVNWCPALGTVLSNEEVI-DGVSERGGHP  181
            EVNTTDP+YYKWTQWIF +LY+KGLAY  EV+VNW   LGT ++NEEV+ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VYRKPMKQWVLKITEYadqlladlddldWPESLKDMQRNWIGRSEGAKVSFDVDNTEGKV  241
            V RKPM+QW+LKIT YA++LL DL+++DWPES+KDMQRNWIG+S GA+V+F V +T+   
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  EVFTTRPDTIYGASFLVLSPEHALVNSITTDEYKEKVKAYQTEASKKSDLERTDLAKDKS  301
             VFTTRPDT++GA++ VL+PEHALV++ITT +  E V  Y+ +AS KSDL RTDLAK+K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAINPLSGEKVQIWIADYVLSTYGTGAIMAVPAHDDRDYEFAKKFDLPiievie  361
            GV TG+YAINP++G  + +WIADYVL++YGTGAIMAVPAHD+RD EFAK+F+L II V+E
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  ggnveeAAYTGEGKHINSGELDGLENEAAITKAIQLLEQKGAGEKKVNYKLRDWLFSRQR  421
            GGNVEEAA+T +G HINS+ LDGL++ +AI+K ++ LE  G G+ +V Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPVIHWEDGTMTTVpeeelplllpeTDEIKPSGTGESPLANIDSFVNVVDEKTGM  481
            YWGEPIP+IHWEDGT T+VPE ELPL+LP T +I+PSGTGESPLAN+   ++V  E  G+
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED-GV  482

Query  482  KGRRETNTMPQWAGSCWYYLRYIDPKNENMLADPEKLKHWLPVDLYIGGVEHAVLHLLYA  541
            KGRRETNTMPQWAGS WYYLRYIDP N + LAD E LK+WLPVD+Y+GG EHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKVLYDLGIVPTKEPFQKLFNQGMILG------------------------------  571
            RFWHKVLYDLG+VPTKEPFQKLFNQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---EGNEKMSKSKGNVINPDDIVQSHGADTLRLYEMFMGPLDAAIAWSEKGLDGSRRFLD  628
               ++  KMSKS  NV+NPDD+V+  GADTLR+YEMFMGPLDA+IAWSE GL+GSR+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RVWRLMVNEDGTLSSKIVTTNNKSLDKVYNQTVKKVTEDFETLGFNTAISQLMVFINECY  688
            RV RL+   +      I   N+ +LDKVYN+TVK VTE+ + + FNTAI+QLMVF+N   
Sbjct  663  RVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  689  KVDEVYKPYIEGFVKMLAPIAPHIGEELWSKL-GHEESITYQPWPTYDEALLVDDEVEIV  747
            K D ++  Y  GFV+++AP+APH+GEELW  L +  ESI+Y PWP+YDE+ LV+++VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  748  VQVNGKLRAKIKIAKDTSKEEMQEIALSNDNVKASIEGKDIMKVIAVPQKLVNIVAK  804
            VQ++GK++AK+ +AKD S+EE+QE+AL+N++V+A I GKDI+KVIAVP+KLVNIV K
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

337) leuS in NC_002745


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  878 bits (3327),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 547/837 (66%), Positives = 674/837 (81%), Gaps = 42/837 (5%)

Query  3    YNHNQIEKKWQDYWDENKTFKTNDNLGQKKFYALDMFPYPSGAGLHVGHPEGYTATDIIS  62
            Y+H  IE KWQ +W +N TFKT  + ++ KFYALDMFPYPSGAGLHVGHPEGYTATDI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRMQGYNVLHPMGWDAFGLPAEQYALDTGNDPREFTKKNIQTFKRQIKELGFSYDWDR  122
            R+KR QG NVLHPMGWDAFGLPAEQYA+DTGNDP EFT  NI  FKRQI+ LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVNTTDPEYYKWTQWIFIQLYNKGLAYVDEVAVNWCPALGTVLSNEEVI-DGVSERGGHP  181
            EVNTTDP+YYKWTQWIF +LY+KGLAY  EV+VNW   LGT ++NEEV+ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VYRKPMKQWVLKITEYadqlladlddldWPESLKDMQRNWIGRSEGAKVSFDVDNTEGKV  241
            V RKPM+QW+LKIT YA++LL DL+++DWPES+KDMQRNWIG+S GA+V+F V +T+   
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  EVFTTRPDTIYGASFLVLSPEHALVNSITTDEYKEKVKAYQTEASKKSDLERTDLAKDKS  301
             VFTTRPDT++GA++ VL+PEHALV++ITT +  E V  Y+ +AS KSDL RTDLAK+K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAINPLSGEKVQIWIADYVLSTYGTGAIMAVPAHDDRDYEFAKKFDLPiievie  361
            GV TG+YAINP++G  + +WIADYVL++YGTGAIMAVPAHD+RD EFAK+F+L II V+E
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  ggnveeAAYTGEGKHINSGELDGLENEAAITKAIQLLEQKGAGEKKVNYKLRDWLFSRQR  421
            GGNVEEAA+T +G HINS+ LDGL++ +AI+K ++ LE  G G+ +V Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPVIHWEDGTMTTVpeeelplllpeTDEIKPSGTGESPLANIDSFVNVVDEKTGM  481
            YWGEPIP+IHWEDGT T+VPE ELPL+LP T +I+PSGTGESPLAN+   ++V  E  G+
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED-GV  482

Query  482  KGRRETNTMPQWAGSCWYYLRYIDPKNENMLADPEKLKHWLPVDLYIGGVEHAVLHLLYA  541
            KGRRETNTMPQWAGS WYYLRYIDP N + LAD E LK+WLPVD+Y+GG EHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKVLYDLGIVPTKEPFQKLFNQGMILG------------------------------  571
            RFWHKVLYDLG+VPTKEPFQKLFNQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---EGNEKMSKSKGNVINPDDIVQSHGADTLRLYEMFMGPLDAAIAWSEKGLDGSRRFLD  628
               ++  KMSKS  NV+NPDD+V+  GADTLR+YEMFMGPLDA+IAWSE GL+GSR+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RVWRLMVNEDGTLSSKIVTTNNKSLDKVYNQTVKKVTEDFETLGFNTAISQLMVFINECY  688
            RV RL+   +      I   N+ +LDKVYN+TVK VTE+ + + FNTAI+QLMVF+N   
Sbjct  663  RVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  689  KVDEVYKPYIEGFVKMLAPIAPHIGEELWSKL-GHEESITYQPWPTYDEALLVDDEVEIV  747
            K D ++  Y  GFV+++AP+APH+GEELW  L +  ESI+Y PWP+YDE+ LV+++VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  748  VQVNGKLRAKIKIAKDTSKEEMQEIALSNDNVKASIEGKDIMKVIAVPQKLVNIVAK  804
            VQ++GK++AK+ +AKD S+EE+QE+AL+N++V+A I GKDI+KVIAVP+KLVNIV K
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

338) leuS in NC_022443


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  878 bits (3326),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 547/837 (66%), Positives = 674/837 (81%), Gaps = 42/837 (5%)

Query  4    YNHNQIEKKWQDYWDENKTFKTNDNLGQKKFYALDMFPYPSGAGLHVGHPEGYTATDIIS  63
            Y+H  IE KWQ +W +N TFKT  + ++ KFYALDMFPYPSGAGLHVGHPEGYTATDI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYKRMQGYNVLHPMGWDAFGLPAEQYALDTGNDPREFTKKNIQTFKRQIKELGFSYDWDR  123
            R+KR QG NVLHPMGWDAFGLPAEQYA+DTGNDP EFT  NI  FKRQI+ LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVNTTDPEYYKWTQWIFIQLYNKGLAYVDEVAVNWCPALGTVLSNEEVI-DGVSERGGHP  182
            EVNTTDP+YYKWTQWIF +LY+KGLAY  EV+VNW   LGT ++NEEV+ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VYRKPMKQWVLKITEYadqlladlddldWPESLKDMQRNWIGRSEGAKVSFDVDNTEGKV  242
            V RKPM+QW+LKIT YA++LL DL+++DWPES+KDMQRNWIG+S GA+V+F V +T+   
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  243  EVFTTRPDTIYGASFLVLSPEHALVNSITTDEYKEKVKAYQTEASKKSDLERTDLAKDKS  302
             VFTTRPDT++GA++ VL+PEHALV++ITT +  E V  Y+ +AS KSDL RTDLAK+K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  303  GVFTGAYAINPLSGEKVQIWIADYVLSTYGTGAIMAVPAHDDRDYEFAKKFDLPiievie  362
            GV TG+YAINP++G  + +WIADYVL++YGTGAIMAVPAHD+RD EFAK+F+L II V+E
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  363  ggnveeAAYTGEGKHINSGELDGLENEAAITKAIQLLEQKGAGEKKVNYKLRDWLFSRQR  422
            GGNVEEAA+T +G HINS+ LDGL++ +AI+K ++ LE  G G+ +V Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  423  YWGEPIPVIHWEDGTMTTVpeeelplllpeTDEIKPSGTGESPLANIDSFVNVVDEKTGM  482
            YWGEPIP+IHWEDGT T+VPE ELPL+LP T +I+PSGTGESPLAN+   ++V  E  G+
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED-GV  482

Query  483  KGRRETNTMPQWAGSCWYYLRYIDPKNENMLADPEKLKHWLPVDLYIGGVEHAVLHLLYA  542
            KGRRETNTMPQWAGS WYYLRYIDP N + LAD E LK+WLPVD+Y+GG EHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  543  RFWHKVLYDLGIVPTKEPFQKLFNQGMILG------------------------------  572
            RFWHKVLYDLG+VPTKEPFQKLFNQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  573  ---EGNEKMSKSKGNVINPDDIVQSHGADTLRLYEMFMGPLDAAIAWSEKGLDGSRRFLD  629
               ++  KMSKS  NV+NPDD+V+  GADTLR+YEMFMGPLDA+IAWSE GL+GSR+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  630  RVWRLMVNEDGTLSSKIVTTNNKSLDKVYNQTVKKVTEDFETLGFNTAISQLMVFINECY  689
            RV RL+   +      I   N+ +LDKVYN+TVK VTE+ + + FNTAI+QLMVF+N   
Sbjct  663  RVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  690  KVDEVYKPYIEGFVKMLAPIAPHIGEELWSKL-GHEESITYQPWPTYDEALLVDDEVEIV  748
            K D ++  Y  GFV+++AP+APH+GEELW  L +  ESI+Y PWP+YDE+ LV+++VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  749  VQVNGKLRAKIKIAKDTSKEEMQEIALSNDNVKASIEGKDIMKVIAVPQKLVNIVAK  805
            VQ++GK++AK+ +AKD S+EE+QE+AL+N++V+A I GKDI+KVIAVP+KLVNIV K
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

339) leuS in NC_022442


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  878 bits (3326),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 547/837 (66%), Positives = 674/837 (81%), Gaps = 42/837 (5%)

Query  4    YNHNQIEKKWQDYWDENKTFKTNDNLGQKKFYALDMFPYPSGAGLHVGHPEGYTATDIIS  63
            Y+H  IE KWQ +W +N TFKT  + ++ KFYALDMFPYPSGAGLHVGHPEGYTATDI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYKRMQGYNVLHPMGWDAFGLPAEQYALDTGNDPREFTKKNIQTFKRQIKELGFSYDWDR  123
            R+KR QG NVLHPMGWDAFGLPAEQYA+DTGNDP EFT  NI  FKRQI+ LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVNTTDPEYYKWTQWIFIQLYNKGLAYVDEVAVNWCPALGTVLSNEEVI-DGVSERGGHP  182
            EVNTTDP+YYKWTQWIF +LY+KGLAY  EV+VNW   LGT ++NEEV+ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VYRKPMKQWVLKITEYadqlladlddldWPESLKDMQRNWIGRSEGAKVSFDVDNTEGKV  242
            V RKPM+QW+LKIT YA++LL DL+++DWPES+KDMQRNWIG+S GA+V+F V +T+   
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  243  EVFTTRPDTIYGASFLVLSPEHALVNSITTDEYKEKVKAYQTEASKKSDLERTDLAKDKS  302
             VFTTRPDT++GA++ VL+PEHALV++ITT +  E V  Y+ +AS KSDL RTDLAK+K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  303  GVFTGAYAINPLSGEKVQIWIADYVLSTYGTGAIMAVPAHDDRDYEFAKKFDLPiievie  362
            GV TG+YAINP++G  + +WIADYVL++YGTGAIMAVPAHD+RD EFAK+F+L II V+E
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  363  ggnveeAAYTGEGKHINSGELDGLENEAAITKAIQLLEQKGAGEKKVNYKLRDWLFSRQR  422
            GGNVEEAA+T +G HINS+ LDGL++ +AI+K ++ LE  G G+ +V Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  423  YWGEPIPVIHWEDGTMTTVpeeelplllpeTDEIKPSGTGESPLANIDSFVNVVDEKTGM  482
            YWGEPIP+IHWEDGT T+VPE ELPL+LP T +I+PSGTGESPLAN+   ++V  E  G+
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED-GV  482

Query  483  KGRRETNTMPQWAGSCWYYLRYIDPKNENMLADPEKLKHWLPVDLYIGGVEHAVLHLLYA  542
            KGRRETNTMPQWAGS WYYLRYIDP N + LAD E LK+WLPVD+Y+GG EHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  543  RFWHKVLYDLGIVPTKEPFQKLFNQGMILG------------------------------  572
            RFWHKVLYDLG+VPTKEPFQKLFNQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  573  ---EGNEKMSKSKGNVINPDDIVQSHGADTLRLYEMFMGPLDAAIAWSEKGLDGSRRFLD  629
               ++  KMSKS  NV+NPDD+V+  GADTLR+YEMFMGPLDA+IAWSE GL+GSR+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  630  RVWRLMVNEDGTLSSKIVTTNNKSLDKVYNQTVKKVTEDFETLGFNTAISQLMVFINECY  689
            RV RL+   +      I   N+ +LDKVYN+TVK VTE+ + + FNTAI+QLMVF+N   
Sbjct  663  RVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  690  KVDEVYKPYIEGFVKMLAPIAPHIGEELWSKL-GHEESITYQPWPTYDEALLVDDEVEIV  748
            K D ++  Y  GFV+++AP+APH+GEELW  L +  ESI+Y PWP+YDE+ LV+++VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  749  VQVNGKLRAKIKIAKDTSKEEMQEIALSNDNVKASIEGKDIMKVIAVPQKLVNIVAK  805
            VQ++GK++AK+ +AKD S+EE+QE+AL+N++V+A I GKDI+KVIAVP+KLVNIV K
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

340) leuS in NC_020529


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  878 bits (3326),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 547/837 (66%), Positives = 674/837 (81%), Gaps = 42/837 (5%)

Query  4    YNHNQIEKKWQDYWDENKTFKTNDNLGQKKFYALDMFPYPSGAGLHVGHPEGYTATDIIS  63
            Y+H  IE KWQ +W +N TFKT  + ++ KFYALDMFPYPSGAGLHVGHPEGYTATDI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYKRMQGYNVLHPMGWDAFGLPAEQYALDTGNDPREFTKKNIQTFKRQIKELGFSYDWDR  123
            R+KR QG NVLHPMGWDAFGLPAEQYA+DTGNDP EFT  NI  FKRQI+ LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVNTTDPEYYKWTQWIFIQLYNKGLAYVDEVAVNWCPALGTVLSNEEVI-DGVSERGGHP  182
            EVNTTDP+YYKWTQWIF +LY+KGLAY  EV+VNW   LGT ++NEEV+ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VYRKPMKQWVLKITEYadqlladlddldWPESLKDMQRNWIGRSEGAKVSFDVDNTEGKV  242
            V RKPM+QW+LKIT YA++LL DL+++DWPES+KDMQRNWIG+S GA+V+F V +T+   
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  243  EVFTTRPDTIYGASFLVLSPEHALVNSITTDEYKEKVKAYQTEASKKSDLERTDLAKDKS  302
             VFTTRPDT++GA++ VL+PEHALV++ITT +  E V  Y+ +AS KSDL RTDLAK+K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  303  GVFTGAYAINPLSGEKVQIWIADYVLSTYGTGAIMAVPAHDDRDYEFAKKFDLPiievie  362
            GV TG+YAINP++G  + +WIADYVL++YGTGAIMAVPAHD+RD EFAK+F+L II V+E
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  363  ggnveeAAYTGEGKHINSGELDGLENEAAITKAIQLLEQKGAGEKKVNYKLRDWLFSRQR  422
            GGNVEEAA+T +G HINS+ LDGL++ +AI+K ++ LE  G G+ +V Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  423  YWGEPIPVIHWEDGTMTTVpeeelplllpeTDEIKPSGTGESPLANIDSFVNVVDEKTGM  482
            YWGEPIP+IHWEDGT T+VPE ELPL+LP T +I+PSGTGESPLAN+   ++V  E  G+
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED-GV  482

Query  483  KGRRETNTMPQWAGSCWYYLRYIDPKNENMLADPEKLKHWLPVDLYIGGVEHAVLHLLYA  542
            KGRRETNTMPQWAGS WYYLRYIDP N + LAD E LK+WLPVD+Y+GG EHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  543  RFWHKVLYDLGIVPTKEPFQKLFNQGMILG------------------------------  572
            RFWHKVLYDLG+VPTKEPFQKLFNQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  573  ---EGNEKMSKSKGNVINPDDIVQSHGADTLRLYEMFMGPLDAAIAWSEKGLDGSRRFLD  629
               ++  KMSKS  NV+NPDD+V+  GADTLR+YEMFMGPLDA+IAWSE GL+GSR+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  630  RVWRLMVNEDGTLSSKIVTTNNKSLDKVYNQTVKKVTEDFETLGFNTAISQLMVFINECY  689
            RV RL+   +      I   N+ +LDKVYN+TVK VTE+ + + FNTAI+QLMVF+N   
Sbjct  663  RVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  690  KVDEVYKPYIEGFVKMLAPIAPHIGEELWSKL-GHEESITYQPWPTYDEALLVDDEVEIV  748
            K D ++  Y  GFV+++AP+APH+GEELW  L +  ESI+Y PWP+YDE+ LV+++VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  749  VQVNGKLRAKIKIAKDTSKEEMQEIALSNDNVKASIEGKDIMKVIAVPQKLVNIVAK  805
            VQ++GK++AK+ +AKD S+EE+QE+AL+N++V+A I GKDI+KVIAVP+KLVNIV K
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

341) leuS in NC_020564


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  878 bits (3326),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 547/837 (66%), Positives = 674/837 (81%), Gaps = 42/837 (5%)

Query  4    YNHNQIEKKWQDYWDENKTFKTNDNLGQKKFYALDMFPYPSGAGLHVGHPEGYTATDIIS  63
            Y+H  IE KWQ +W +N TFKT  + ++ KFYALDMFPYPSGAGLHVGHPEGYTATDI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYKRMQGYNVLHPMGWDAFGLPAEQYALDTGNDPREFTKKNIQTFKRQIKELGFSYDWDR  123
            R+KR QG NVLHPMGWDAFGLPAEQYA+DTGNDP EFT  NI  FKRQI+ LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVNTTDPEYYKWTQWIFIQLYNKGLAYVDEVAVNWCPALGTVLSNEEVI-DGVSERGGHP  182
            EVNTTDP+YYKWTQWIF +LY+KGLAY  EV+VNW   LGT ++NEEV+ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VYRKPMKQWVLKITEYadqlladlddldWPESLKDMQRNWIGRSEGAKVSFDVDNTEGKV  242
            V RKPM+QW+LKIT YA++LL DL+++DWPES+KDMQRNWIG+S GA+V+F V +T+   
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  243  EVFTTRPDTIYGASFLVLSPEHALVNSITTDEYKEKVKAYQTEASKKSDLERTDLAKDKS  302
             VFTTRPDT++GA++ VL+PEHALV++ITT +  E V  Y+ +AS KSDL RTDLAK+K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  303  GVFTGAYAINPLSGEKVQIWIADYVLSTYGTGAIMAVPAHDDRDYEFAKKFDLPiievie  362
            GV TG+YAINP++G  + +WIADYVL++YGTGAIMAVPAHD+RD EFAK+F+L II V+E
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  363  ggnveeAAYTGEGKHINSGELDGLENEAAITKAIQLLEQKGAGEKKVNYKLRDWLFSRQR  422
            GGNVEEAA+T +G HINS+ LDGL++ +AI+K ++ LE  G G+ +V Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  423  YWGEPIPVIHWEDGTMTTVpeeelplllpeTDEIKPSGTGESPLANIDSFVNVVDEKTGM  482
            YWGEPIP+IHWEDGT T+VPE ELPL+LP T +I+PSGTGESPLAN+   ++V  E  G+
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED-GV  482

Query  483  KGRRETNTMPQWAGSCWYYLRYIDPKNENMLADPEKLKHWLPVDLYIGGVEHAVLHLLYA  542
            KGRRETNTMPQWAGS WYYLRYIDP N + LAD E LK+WLPVD+Y+GG EHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  543  RFWHKVLYDLGIVPTKEPFQKLFNQGMILG------------------------------  572
            RFWHKVLYDLG+VPTKEPFQKLFNQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  573  ---EGNEKMSKSKGNVINPDDIVQSHGADTLRLYEMFMGPLDAAIAWSEKGLDGSRRFLD  629
               ++  KMSKS  NV+NPDD+V+  GADTLR+YEMFMGPLDA+IAWSE GL+GSR+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  630  RVWRLMVNEDGTLSSKIVTTNNKSLDKVYNQTVKKVTEDFETLGFNTAISQLMVFINECY  689
            RV RL+   +      I   N+ +LDKVYN+TVK VTE+ + + FNTAI+QLMVF+N   
Sbjct  663  RVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  690  KVDEVYKPYIEGFVKMLAPIAPHIGEELWSKL-GHEESITYQPWPTYDEALLVDDEVEIV  748
            K D ++  Y  GFV+++AP+APH+GEELW  L +  ESI+Y PWP+YDE+ LV+++VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  749  VQVNGKLRAKIKIAKDTSKEEMQEIALSNDNVKASIEGKDIMKVIAVPQKLVNIVAK  805
            VQ++GK++AK+ +AKD S+EE+QE+AL+N++V+A I GKDI+KVIAVP+KLVNIV K
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

342) leuS in NC_020532


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  878 bits (3326),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 547/837 (66%), Positives = 674/837 (81%), Gaps = 42/837 (5%)

Query  4    YNHNQIEKKWQDYWDENKTFKTNDNLGQKKFYALDMFPYPSGAGLHVGHPEGYTATDIIS  63
            Y+H  IE KWQ +W +N TFKT  + ++ KFYALDMFPYPSGAGLHVGHPEGYTATDI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYKRMQGYNVLHPMGWDAFGLPAEQYALDTGNDPREFTKKNIQTFKRQIKELGFSYDWDR  123
            R+KR QG NVLHPMGWDAFGLPAEQYA+DTGNDP EFT  NI  FKRQI+ LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVNTTDPEYYKWTQWIFIQLYNKGLAYVDEVAVNWCPALGTVLSNEEVI-DGVSERGGHP  182
            EVNTTDP+YYKWTQWIF +LY+KGLAY  EV+VNW   LGT ++NEEV+ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VYRKPMKQWVLKITEYadqlladlddldWPESLKDMQRNWIGRSEGAKVSFDVDNTEGKV  242
            V RKPM+QW+LKIT YA++LL DL+++DWPES+KDMQRNWIG+S GA+V+F V +T+   
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  243  EVFTTRPDTIYGASFLVLSPEHALVNSITTDEYKEKVKAYQTEASKKSDLERTDLAKDKS  302
             VFTTRPDT++GA++ VL+PEHALV++ITT +  E V  Y+ +AS KSDL RTDLAK+K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  303  GVFTGAYAINPLSGEKVQIWIADYVLSTYGTGAIMAVPAHDDRDYEFAKKFDLPiievie  362
            GV TG+YAINP++G  + +WIADYVL++YGTGAIMAVPAHD+RD EFAK+F+L II V+E
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  363  ggnveeAAYTGEGKHINSGELDGLENEAAITKAIQLLEQKGAGEKKVNYKLRDWLFSRQR  422
            GGNVEEAA+T +G HINS+ LDGL++ +AI+K ++ LE  G G+ +V Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  423  YWGEPIPVIHWEDGTMTTVpeeelplllpeTDEIKPSGTGESPLANIDSFVNVVDEKTGM  482
            YWGEPIP+IHWEDGT T+VPE ELPL+LP T +I+PSGTGESPLAN+   ++V  E  G+
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED-GV  482

Query  483  KGRRETNTMPQWAGSCWYYLRYIDPKNENMLADPEKLKHWLPVDLYIGGVEHAVLHLLYA  542
            KGRRETNTMPQWAGS WYYLRYIDP N + LAD E LK+WLPVD+Y+GG EHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  543  RFWHKVLYDLGIVPTKEPFQKLFNQGMILG------------------------------  572
            RFWHKVLYDLG+VPTKEPFQKLFNQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  573  ---EGNEKMSKSKGNVINPDDIVQSHGADTLRLYEMFMGPLDAAIAWSEKGLDGSRRFLD  629
               ++  KMSKS  NV+NPDD+V+  GADTLR+YEMFMGPLDA+IAWSE GL+GSR+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  630  RVWRLMVNEDGTLSSKIVTTNNKSLDKVYNQTVKKVTEDFETLGFNTAISQLMVFINECY  689
            RV RL+   +      I   N+ +LDKVYN+TVK VTE+ + + FNTAI+QLMVF+N   
Sbjct  663  RVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  690  KVDEVYKPYIEGFVKMLAPIAPHIGEELWSKL-GHEESITYQPWPTYDEALLVDDEVEIV  748
            K D ++  Y  GFV+++AP+APH+GEELW  L +  ESI+Y PWP+YDE+ LV+++VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  749  VQVNGKLRAKIKIAKDTSKEEMQEIALSNDNVKASIEGKDIMKVIAVPQKLVNIVAK  805
            VQ++GK++AK+ +AKD S+EE+QE+AL+N++V+A I GKDI+KVIAVP+KLVNIV K
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

343) leuS in NC_020533


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  878 bits (3326),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 547/837 (66%), Positives = 674/837 (81%), Gaps = 42/837 (5%)

Query  4    YNHNQIEKKWQDYWDENKTFKTNDNLGQKKFYALDMFPYPSGAGLHVGHPEGYTATDIIS  63
            Y+H  IE KWQ +W +N TFKT  + ++ KFYALDMFPYPSGAGLHVGHPEGYTATDI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYKRMQGYNVLHPMGWDAFGLPAEQYALDTGNDPREFTKKNIQTFKRQIKELGFSYDWDR  123
            R+KR QG NVLHPMGWDAFGLPAEQYA+DTGNDP EFT  NI  FKRQI+ LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVNTTDPEYYKWTQWIFIQLYNKGLAYVDEVAVNWCPALGTVLSNEEVI-DGVSERGGHP  182
            EVNTTDP+YYKWTQWIF +LY+KGLAY  EV+VNW   LGT ++NEEV+ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VYRKPMKQWVLKITEYadqlladlddldWPESLKDMQRNWIGRSEGAKVSFDVDNTEGKV  242
            V RKPM+QW+LKIT YA++LL DL+++DWPES+KDMQRNWIG+S GA+V+F V +T+   
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  243  EVFTTRPDTIYGASFLVLSPEHALVNSITTDEYKEKVKAYQTEASKKSDLERTDLAKDKS  302
             VFTTRPDT++GA++ VL+PEHALV++ITT +  E V  Y+ +AS KSDL RTDLAK+K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  303  GVFTGAYAINPLSGEKVQIWIADYVLSTYGTGAIMAVPAHDDRDYEFAKKFDLPiievie  362
            GV TG+YAINP++G  + +WIADYVL++YGTGAIMAVPAHD+RD EFAK+F+L II V+E
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  363  ggnveeAAYTGEGKHINSGELDGLENEAAITKAIQLLEQKGAGEKKVNYKLRDWLFSRQR  422
            GGNVEEAA+T +G HINS+ LDGL++ +AI+K ++ LE  G G+ +V Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  423  YWGEPIPVIHWEDGTMTTVpeeelplllpeTDEIKPSGTGESPLANIDSFVNVVDEKTGM  482
            YWGEPIP+IHWEDGT T+VPE ELPL+LP T +I+PSGTGESPLAN+   ++V  E  G+
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED-GV  482

Query  483  KGRRETNTMPQWAGSCWYYLRYIDPKNENMLADPEKLKHWLPVDLYIGGVEHAVLHLLYA  542
            KGRRETNTMPQWAGS WYYLRYIDP N + LAD E LK+WLPVD+Y+GG EHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  543  RFWHKVLYDLGIVPTKEPFQKLFNQGMILG------------------------------  572
            RFWHKVLYDLG+VPTKEPFQKLFNQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  573  ---EGNEKMSKSKGNVINPDDIVQSHGADTLRLYEMFMGPLDAAIAWSEKGLDGSRRFLD  629
               ++  KMSKS  NV+NPDD+V+  GADTLR+YEMFMGPLDA+IAWSE GL+GSR+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  630  RVWRLMVNEDGTLSSKIVTTNNKSLDKVYNQTVKKVTEDFETLGFNTAISQLMVFINECY  689
            RV RL+   +      I   N+ +LDKVYN+TVK VTE+ + + FNTAI+QLMVF+N   
Sbjct  663  RVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  690  KVDEVYKPYIEGFVKMLAPIAPHIGEELWSKL-GHEESITYQPWPTYDEALLVDDEVEIV  748
            K D ++  Y  GFV+++AP+APH+GEELW  L +  ESI+Y PWP+YDE+ LV+++VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  749  VQVNGKLRAKIKIAKDTSKEEMQEIALSNDNVKASIEGKDIMKVIAVPQKLVNIVAK  805
            VQ++GK++AK+ +AKD S+EE+QE+AL+N++V+A I GKDI+KVIAVP+KLVNIV K
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

344) leuS in NC_020537


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  878 bits (3326),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 547/837 (66%), Positives = 674/837 (81%), Gaps = 42/837 (5%)

Query  4    YNHNQIEKKWQDYWDENKTFKTNDNLGQKKFYALDMFPYPSGAGLHVGHPEGYTATDIIS  63
            Y+H  IE KWQ +W +N TFKT  + ++ KFYALDMFPYPSGAGLHVGHPEGYTATDI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYKRMQGYNVLHPMGWDAFGLPAEQYALDTGNDPREFTKKNIQTFKRQIKELGFSYDWDR  123
            R+KR QG NVLHPMGWDAFGLPAEQYA+DTGNDP EFT  NI  FKRQI+ LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVNTTDPEYYKWTQWIFIQLYNKGLAYVDEVAVNWCPALGTVLSNEEVI-DGVSERGGHP  182
            EVNTTDP+YYKWTQWIF +LY+KGLAY  EV+VNW   LGT ++NEEV+ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VYRKPMKQWVLKITEYadqlladlddldWPESLKDMQRNWIGRSEGAKVSFDVDNTEGKV  242
            V RKPM+QW+LKIT YA++LL DL+++DWPES+KDMQRNWIG+S GA+V+F V +T+   
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  243  EVFTTRPDTIYGASFLVLSPEHALVNSITTDEYKEKVKAYQTEASKKSDLERTDLAKDKS  302
             VFTTRPDT++GA++ VL+PEHALV++ITT +  E V  Y+ +AS KSDL RTDLAK+K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  303  GVFTGAYAINPLSGEKVQIWIADYVLSTYGTGAIMAVPAHDDRDYEFAKKFDLPiievie  362
            GV TG+YAINP++G  + +WIADYVL++YGTGAIMAVPAHD+RD EFAK+F+L II V+E
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  363  ggnveeAAYTGEGKHINSGELDGLENEAAITKAIQLLEQKGAGEKKVNYKLRDWLFSRQR  422
            GGNVEEAA+T +G HINS+ LDGL++ +AI+K ++ LE  G G+ +V Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  423  YWGEPIPVIHWEDGTMTTVpeeelplllpeTDEIKPSGTGESPLANIDSFVNVVDEKTGM  482
            YWGEPIP+IHWEDGT T+VPE ELPL+LP T +I+PSGTGESPLAN+   ++V  E  G+
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED-GV  482

Query  483  KGRRETNTMPQWAGSCWYYLRYIDPKNENMLADPEKLKHWLPVDLYIGGVEHAVLHLLYA  542
            KGRRETNTMPQWAGS WYYLRYIDP N + LAD E LK+WLPVD+Y+GG EHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  543  RFWHKVLYDLGIVPTKEPFQKLFNQGMILG------------------------------  572
            RFWHKVLYDLG+VPTKEPFQKLFNQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  573  ---EGNEKMSKSKGNVINPDDIVQSHGADTLRLYEMFMGPLDAAIAWSEKGLDGSRRFLD  629
               ++  KMSKS  NV+NPDD+V+  GADTLR+YEMFMGPLDA+IAWSE GL+GSR+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  630  RVWRLMVNEDGTLSSKIVTTNNKSLDKVYNQTVKKVTEDFETLGFNTAISQLMVFINECY  689
            RV RL+   +      I   N+ +LDKVYN+TVK VTE+ + + FNTAI+QLMVF+N   
Sbjct  663  RVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  690  KVDEVYKPYIEGFVKMLAPIAPHIGEELWSKL-GHEESITYQPWPTYDEALLVDDEVEIV  748
            K D ++  Y  GFV+++AP+APH+GEELW  L +  ESI+Y PWP+YDE+ LV+++VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  749  VQVNGKLRAKIKIAKDTSKEEMQEIALSNDNVKASIEGKDIMKVIAVPQKLVNIVAK  805
            VQ++GK++AK+ +AKD S+EE+QE+AL+N++V+A I GKDI+KVIAVP+KLVNIV K
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

345) leuS in NC_017333


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  878 bits (3325),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 546/837 (66%), Positives = 674/837 (81%), Gaps = 42/837 (5%)

Query  4    YNHNQIEKKWQDYWDENKTFKTNDNLGQKKFYALDMFPYPSGAGLHVGHPEGYTATDIIS  63
            Y+H  IE KWQ +W +N TFKT  + ++ KFYALDMFPYPSGAGLHVGHPEGYTATDI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYKRMQGYNVLHPMGWDAFGLPAEQYALDTGNDPREFTKKNIQTFKRQIKELGFSYDWDR  123
            R+KR QG NVLHPMGWDAFGLPAEQYA+DTGNDP EFT  NI  FKRQI+ LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVNTTDPEYYKWTQWIFIQLYNKGLAYVDEVAVNWCPALGTVLSNEEVI-DGVSERGGHP  182
            EVNTTDP+YYKWTQWIF +LY+KGLAY  EV+VNW   LGT ++NEEV+ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VYRKPMKQWVLKITEYadqlladlddldWPESLKDMQRNWIGRSEGAKVSFDVDNAEGKV  242
            V RKPM+QW+LKIT YA++LL DL+++DWPES+KDMQRNWIG+S GA+V+F V +++   
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  243  EVFTTRPDTIYGASFLVLSPEHALVDSITTDEYKDQVKAYQTEASKKSDLERTDLAKDKS  302
             VFTTRPDT++GA++ VL+PEHALVD+ITT +  + V  Y+ +AS KSDL RTDLAK+K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  303  GVFTGAYAINPLSGEKVQIWIADYVLSTYGTGAIMAVPAHDDRDYEFAKKFDLPiievie  362
            GV TG+YAINP++G  + +WIADYVL++YGTGAIMAVPAHD+RD EFAK+F+L II V+E
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  363  ggnveeAAYTGEGKHINSGELDGLENEAAITKAIQLLEQKGAGEKKVNYKLRDWLFSRQR  422
            GGNVEEAA+T +G HINS+ LDGL++ +AI+K ++ LE  G G+ +V Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  423  YWGEPIPVIHWEDGTMTTVpeeelplllpeTDEIKPSGTGESPLANIDSFVNVVDEKTGM  482
            YWGEPIP+IHWEDGT T+VPE ELPL+LP T +I+PSGTGESPLAN+   ++V  E  G+
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED-GV  482

Query  483  KGRRETNTMPQWAGSCWYYLRYIDPKNENMLADPEKLKHWLPVDLYIGGVEHAVLHLLYA  542
            KGRRETNTMPQWAGS WYYLRYIDP N + LAD E LK+WLPVD+Y+GG EHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  543  RFWHKVLYDLGIVPTKEPFQKLFNQGMILG------------------------------  572
            RFWHKVLYDLG+VPTKEPFQKLFNQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  573  ---EGNEKMSKSKGNVINPDDIVQSHGADTLRLYEMFMGPLDAAIAWSEKGLDGSRRFLD  629
               ++  KMSKS  NV+NPDD+V+  GADTLR+YEMFMGPLDA+IAWSE GL+GSR+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  630  RVWRLMVNEDGTLSSKIVTTNNKSLDKVYNQTVKKVTEDFETLGFNTAISQLMVFINECY  689
            RV RL+   +      I   N+ +LDKVYN+TVK VTE+ + + FNTAI+QLMVF+N   
Sbjct  663  RVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  690  KVDEVYKPYIEGFVKMLAPIAPHIGEELWSKL-GHEESITYQPWPTYDEALLVDDEVEIV  748
            K D ++  Y  GFV+++AP+APH+GEELW  L +  ESI+Y PWP+YDE+ LV+++VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  749  VQVNGKLRAKIKIAKDTSKEEMQEIALSNDNVKASIEGKDIMKVIAVPQKLVNIVAK  805
            VQ++GK++AK+ +AKD S+EE+QE+AL+N++V+A I GKDI+KVIAVP+KLVNIV K
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

346) leuS in NC_017342


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  878 bits (3324),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 546/837 (66%), Positives = 674/837 (81%), Gaps = 42/837 (5%)

Query  4    YNHNQIEKKWQDYWDENKTFKTNDNLGQKKFYALDMFPYPSGAGLHVGHPEGYTATDIIS  63
            Y+H  IE KWQ +W +N TFKT  + ++ KFYALDMFPYPSGAGLHVGHPEGYTATDI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYKRMQGYNVLHPMGWDAFGLPAEQYALDTGNDPREFTKKNIQTFKRQIKELGFSYDWDR  123
            R+KR QG NVLHPMGWDAFGLPAEQYA+DTGNDP EFT  NI  FKRQI+ LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVNTTDPEYYKWTQWIFIQLYNKGLAYVDEVAVNWCPALGTVLSNEEVI-DGVSERGGHP  182
            EVNTTDP+YYKWTQWIF +LY+KGLAY  EV+VNW   LGT ++NEEV+ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VYRKPMKQWVLKITEYadqlladlddldWPESLKDMQRNWIGRSEGAKVSFDVDNSEGKV  242
            V RKPM+QW+LKIT YA++LL DL+++DWPES+KDMQRNWIG+S GA+V+F V +++   
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  243  EVFTTRPDTIYGASFLVLSPEHALVDSITTDEYKDQVKAYQTEASKKSDLERTDLAKDKS  302
             VFTTRPDT++GA++ VL+PEHALVD+ITT +  + V  Y+ +AS KSDL RTDLAK+K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  303  GVFTGAYAINPLSGEKVQIWIADYVLSTYGTGAIMAVPAHDDRDYEFAKKFDLPiievie  362
            GV TG+YAINP++G  + +WIADYVL++YGTGAIMAVPAHD+RD EFAK+F+L II V+E
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  363  ggnveeAAYTGEGKHINSGELDGLENEAAITKAIQLLEKKGAGEKKVNYKLRDWLFSRQR  422
            GGNVEEAA+T +G HINS+ LDGL++ +AI+K ++ LE  G G+ +V Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  423  YWGEPIPVIHWEDGTMTTVpeeelplllpeTDEIKPSGTGESPLANIDSFVNVVDEKTGM  482
            YWGEPIP+IHWEDGT T+VPE ELPL+LP T +I+PSGTGESPLAN+   ++V  E  G+
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED-GV  482

Query  483  KGRRETNTMPQWAGSCWYYLRYIDPKNENMLADPEKLKHWLPVDLYIGGVEHAVLHLLYA  542
            KGRRETNTMPQWAGS WYYLRYIDP N + LAD E LK+WLPVD+Y+GG EHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  543  RFWHKVLYDLGIVPTKEPFQKLFNQGMILG------------------------------  572
            RFWHKVLYDLG+VPTKEPFQKLFNQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  573  ---EGNEKMSKSKGNVINPDDIVQSHGADTLRLYEMFMGPLDAAIAWSEKGLDGSRRFLD  629
               ++  KMSKS  NV+NPDD+V+  GADTLR+YEMFMGPLDA+IAWSE GL+GSR+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  630  RVWRLMVNEDGTLSSKIVTTNNKSLDKVYNQTVKKVTEDFETLGFNTAISQLMVFINECY  689
            RV RL+   +      I   N+ +LDKVYN+TVK VTE+ + + FNTAI+QLMVF+N   
Sbjct  663  RVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  690  KVDEVYKPYIEGFVKMLAPIAPHIGEELWSKL-GHEESITYQPWPTYDEALLVDDEVEIV  748
            K D ++  Y  GFV+++AP+APH+GEELW  L +  ESI+Y PWP+YDE+ LV+++VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  749  VQVNGKLRAKIKIAKDTSKEEMQEIALSNDNVKASIEGKDIMKVIAVPQKLVNIVAK  805
            VQ++GK++AK+ +AKD S+EE+QE+AL+N++V+A I GKDI+KVIAVP+KLVNIV K
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

347) leuS in NC_020566


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  878 bits (3326),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 547/837 (66%), Positives = 674/837 (81%), Gaps = 42/837 (5%)

Query  4    YNHNQIEKKWQDYWDENKTFKTNDNLGQKKFYALDMFPYPSGAGLHVGHPEGYTATDIIS  63
            Y+H  IE KWQ +W +N TFKT  + ++ KFYALDMFPYPSGAGLHVGHPEGYTATDI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYKRMQGYNVLHPMGWDAFGLPAEQYALDTGNDPREFTKKNIQTFKRQIKELGFSYDWDR  123
            R+KR QG NVLHPMGWDAFGLPAEQYA+DTGNDP EFT  NI  FKRQI+ LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVNTTDPEYYKWTQWIFIQLYNKGLAYVDEVAVNWCPALGTVLSNEEVI-DGVSERGGHP  182
            EVNTTDP+YYKWTQWIF +LY+KGLAY  EV+VNW   LGT ++NEEV+ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VYRKPMKQWVLKITEYadqlladlddldWPESLKDMQRNWIGRSEGAKVSFDVDNTEGKV  242
            V RKPM+QW+LKIT YA++LL DL+++DWPES+KDMQRNWIG+S GA+V+F V +T+   
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  243  EVFTTRPDTIYGASFLVLSPEHALVNSITTDEYKEKVKAYQTEASKKSDLERTDLAKDKS  302
             VFTTRPDT++GA++ VL+PEHALV++ITT +  E V  Y+ +AS KSDL RTDLAK+K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  303  GVFTGAYAINPLSGEKVQIWIADYVLSTYGTGAIMAVPAHDDRDYEFAKKFDLPiievie  362
            GV TG+YAINP++G  + +WIADYVL++YGTGAIMAVPAHD+RD EFAK+F+L II V+E
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  363  ggnveeAAYTGEGKHINSGELDGLENEAAITKAIQLLEQKGAGEKKVNYKLRDWLFSRQR  422
            GGNVEEAA+T +G HINS+ LDGL++ +AI+K ++ LE  G G+ +V Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  423  YWGEPIPVIHWEDGTMTTVpeeelplllpeTDEIKPSGTGESPLANIDSFVNVVDEKTGM  482
            YWGEPIP+IHWEDGT T+VPE ELPL+LP T +I+PSGTGESPLAN+   ++V  E  G+
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED-GV  482

Query  483  KGRRETNTMPQWAGSCWYYLRYIDPKNENMLADPEKLKHWLPVDLYIGGVEHAVLHLLYA  542
            KGRRETNTMPQWAGS WYYLRYIDP N + LAD E LK+WLPVD+Y+GG EHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  543  RFWHKVLYDLGIVPTKEPFQKLFNQGMILG------------------------------  572
            RFWHKVLYDLG+VPTKEPFQKLFNQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  573  ---EGNEKMSKSKGNVINPDDIVQSHGADTLRLYEMFMGPLDAAIAWSEKGLDGSRRFLD  629
               ++  KMSKS  NV+NPDD+V+  GADTLR+YEMFMGPLDA+IAWSE GL+GSR+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  630  RVWRLMVNEDGTLSSKIVTTNNKSLDKVYNQTVKKVTEDFETLGFNTAISQLMVFINECY  689
            RV RL+   +      I   N+ +LDKVYN+TVK VTE+ + + FNTAI+QLMVF+N   
Sbjct  663  RVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  690  KVDEVYKPYIEGFVKMLAPIAPHIGEELWSKL-GHEESITYQPWPTYDEALLVDDEVEIV  748
            K D ++  Y  GFV+++AP+APH+GEELW  L +  ESI+Y PWP+YDE+ LV+++VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  749  VQVNGKLRAKIKIAKDTSKEEMQEIALSNDNVKASIEGKDIMKVIAVPQKLVNIVAK  805
            VQ++GK++AK+ +AKD S+EE+QE+AL+N++V+A I GKDI+KVIAVP+KLVNIV K
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

348) leuS in NC_020536


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  878 bits (3326),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 547/837 (66%), Positives = 674/837 (81%), Gaps = 42/837 (5%)

Query  4    YNHNQIEKKWQDYWDENKTFKTNDNLGQKKFYALDMFPYPSGAGLHVGHPEGYTATDIIS  63
            Y+H  IE KWQ +W +N TFKT  + ++ KFYALDMFPYPSGAGLHVGHPEGYTATDI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYKRMQGYNVLHPMGWDAFGLPAEQYALDTGNDPREFTKKNIQTFKRQIKELGFSYDWDR  123
            R+KR QG NVLHPMGWDAFGLPAEQYA+DTGNDP EFT  NI  FKRQI+ LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVNTTDPEYYKWTQWIFIQLYNKGLAYVDEVAVNWCPALGTVLSNEEVI-DGVSERGGHP  182
            EVNTTDP+YYKWTQWIF +LY+KGLAY  EV+VNW   LGT ++NEEV+ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VYRKPMKQWVLKITEYadqlladlddldWPESLKDMQRNWIGRSEGAKVSFDVDNTEGKV  242
            V RKPM+QW+LKIT YA++LL DL+++DWPES+KDMQRNWIG+S GA+V+F V +T+   
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  243  EVFTTRPDTIYGASFLVLSPEHALVNSITTDEYKEKVKAYQTEASKKSDLERTDLAKDKS  302
             VFTTRPDT++GA++ VL+PEHALV++ITT +  E V  Y+ +AS KSDL RTDLAK+K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  303  GVFTGAYAINPLSGEKVQIWIADYVLSTYGTGAIMAVPAHDDRDYEFAKKFDLPiievie  362
            GV TG+YAINP++G  + +WIADYVL++YGTGAIMAVPAHD+RD EFAK+F+L II V+E
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  363  ggnveeAAYTGEGKHINSGELDGLENEAAITKAIQLLEQKGAGEKKVNYKLRDWLFSRQR  422
            GGNVEEAA+T +G HINS+ LDGL++ +AI+K ++ LE  G G+ +V Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  423  YWGEPIPVIHWEDGTMTTVpeeelplllpeTDEIKPSGTGESPLANIDSFVNVVDEKTGM  482
            YWGEPIP+IHWEDGT T+VPE ELPL+LP T +I+PSGTGESPLAN+   ++V  E  G+
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED-GV  482

Query  483  KGRRETNTMPQWAGSCWYYLRYIDPKNENMLADPEKLKHWLPVDLYIGGVEHAVLHLLYA  542
            KGRRETNTMPQWAGS WYYLRYIDP N + LAD E LK+WLPVD+Y+GG EHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  543  RFWHKVLYDLGIVPTKEPFQKLFNQGMILG------------------------------  572
            RFWHKVLYDLG+VPTKEPFQKLFNQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  573  ---EGNEKMSKSKGNVINPDDIVQSHGADTLRLYEMFMGPLDAAIAWSEKGLDGSRRFLD  629
               ++  KMSKS  NV+NPDD+V+  GADTLR+YEMFMGPLDA+IAWSE GL+GSR+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  630  RVWRLMVNEDGTLSSKIVTTNNKSLDKVYNQTVKKVTEDFETLGFNTAISQLMVFINECY  689
            RV RL+   +      I   N+ +LDKVYN+TVK VTE+ + + FNTAI+QLMVF+N   
Sbjct  663  RVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  690  KVDEVYKPYIEGFVKMLAPIAPHIGEELWSKL-GHEESITYQPWPTYDEALLVDDEVEIV  748
            K D ++  Y  GFV+++AP+APH+GEELW  L +  ESI+Y PWP+YDE+ LV+++VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  749  VQVNGKLRAKIKIAKDTSKEEMQEIALSNDNVKASIEGKDIMKVIAVPQKLVNIVAK  805
            VQ++GK++AK+ +AKD S+EE+QE+AL+N++V+A I GKDI+KVIAVP+KLVNIV K
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

349) leuS in NC_020568


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  878 bits (3326),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 547/837 (66%), Positives = 674/837 (81%), Gaps = 42/837 (5%)

Query  4    YNHNQIEKKWQDYWDENKTFKTNDNLGQKKFYALDMFPYPSGAGLHVGHPEGYTATDIIS  63
            Y+H  IE KWQ +W +N TFKT  + ++ KFYALDMFPYPSGAGLHVGHPEGYTATDI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYKRMQGYNVLHPMGWDAFGLPAEQYALDTGNDPREFTKKNIQTFKRQIKELGFSYDWDR  123
            R+KR QG NVLHPMGWDAFGLPAEQYA+DTGNDP EFT  NI  FKRQI+ LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVNTTDPEYYKWTQWIFIQLYNKGLAYVDEVAVNWCPALGTVLSNEEVI-DGVSERGGHP  182
            EVNTTDP+YYKWTQWIF +LY+KGLAY  EV+VNW   LGT ++NEEV+ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VYRKPMKQWVLKITEYadqlladlddldWPESLKDMQRNWIGRSEGAKVSFDVDNTEGKV  242
            V RKPM+QW+LKIT YA++LL DL+++DWPES+KDMQRNWIG+S GA+V+F V +T+   
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  243  EVFTTRPDTIYGASFLVLSPEHALVNSITTDEYKEKVKAYQTEASKKSDLERTDLAKDKS  302
             VFTTRPDT++GA++ VL+PEHALV++ITT +  E V  Y+ +AS KSDL RTDLAK+K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  303  GVFTGAYAINPLSGEKVQIWIADYVLSTYGTGAIMAVPAHDDRDYEFAKKFDLPiievie  362
            GV TG+YAINP++G  + +WIADYVL++YGTGAIMAVPAHD+RD EFAK+F+L II V+E
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  363  ggnveeAAYTGEGKHINSGELDGLENEAAITKAIQLLEQKGAGEKKVNYKLRDWLFSRQR  422
            GGNVEEAA+T +G HINS+ LDGL++ +AI+K ++ LE  G G+ +V Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  423  YWGEPIPVIHWEDGTMTTVpeeelplllpeTDEIKPSGTGESPLANIDSFVNVVDEKTGM  482
            YWGEPIP+IHWEDGT T+VPE ELPL+LP T +I+PSGTGESPLAN+   ++V  E  G+
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED-GV  482

Query  483  KGRRETNTMPQWAGSCWYYLRYIDPKNENMLADPEKLKHWLPVDLYIGGVEHAVLHLLYA  542
            KGRRETNTMPQWAGS WYYLRYIDP N + LAD E LK+WLPVD+Y+GG EHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  543  RFWHKVLYDLGIVPTKEPFQKLFNQGMILG------------------------------  572
            RFWHKVLYDLG+VPTKEPFQKLFNQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  573  ---EGNEKMSKSKGNVINPDDIVQSHGADTLRLYEMFMGPLDAAIAWSEKGLDGSRRFLD  629
               ++  KMSKS  NV+NPDD+V+  GADTLR+YEMFMGPLDA+IAWSE GL+GSR+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  630  RVWRLMVNEDGTLSSKIVTTNNKSLDKVYNQTVKKVTEDFETLGFNTAISQLMVFINECY  689
            RV RL+   +      I   N+ +LDKVYN+TVK VTE+ + + FNTAI+QLMVF+N   
Sbjct  663  RVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  690  KVDEVYKPYIEGFVKMLAPIAPHIGEELWSKL-GHEESITYQPWPTYDEALLVDDEVEIV  748
            K D ++  Y  GFV+++AP+APH+GEELW  L +  ESI+Y PWP+YDE+ LV+++VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  749  VQVNGKLRAKIKIAKDTSKEEMQEIALSNDNVKASIEGKDIMKVIAVPQKLVNIVAK  805
            VQ++GK++AK+ +AKD S+EE+QE+AL+N++V+A I GKDI+KVIAVP+KLVNIV K
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

350) leuS in NC_017491


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  878 bits (3325),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 529/819 (65%), Positives = 655/819 (80%), Gaps = 41/819 (5%)

Query  3    YDHHEIDKKWQRYWAEHNEFNTTTDPKKPNYYALDMFPYPSGQGLHVGHPEGYTATDIVA  62
            YDH  I+ KWQ +WA+++ F+T TD+ KP++YALDMFPYPSG GLHVGHPEGYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMKRMQGFNVLHPMGWDAFGLPAEQYALNTGHNPRTFTKQNIETFKRQINSLGFSYDWNR  122
            R KR QG NVLHPMGWDAFGLPAEQYA++TG++P  FT +NI  FKRQIN+LGFSYDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EINTTDPNYYKWTQWIFEQLYKHGLAYEAEVPVNWSPDLGTVVANEEVI-DGKTERGGFP  181
            E+NTTDPNYYKWTQWIF +LY  GLAYEAEVPVNW  +LGT +ANEEV+ DG +ERGG+P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VVRKPMRQWMLKITAYadklladlddldWPESIKQMQRNWIGKSTGAQITFTVTDTQEKF  241
            VVRKPMRQWMLKITAYA++LL DL+++DWPESIK+MQRNWIGKSTGA++TF V DT+  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  DVFTTRPDTLFGATYVVMAPEHDLVEKITTPEQQAVVDAYIEEAAHKSDLDRTALDKEKT  301
             VFTTRPDTLFGATY V+APEH LV+ ITT++Q   V  Y  +A+ KSDL RT L KEKT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVWTGAYATNPVNGEKLPIWISDYVLATYGTGAIMAVPAHDDRDYAFAKKFGIEIKPVIE  361
            GVWTG+YA NPVNG  +P+WI+DYVLA+YGTGAIMAVPAHD+RD  FAK+F ++I PV+E
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGNIDEAAYTGDGVHINSGFLDGLNEQDAIDRMIAWLEDKGIGQEKVNYKLRDWVFSRQR  421
            GGN++EAA+T DG+HINS+FLDGL+   AI +M+ WLE  G+G+E+V Y+LRDW+FSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPVIHWEDGettlvpedelpltlpeevdIKPSGTGESPLANLTDWVNVVDKNGRK  481
            YWGEPIP+IHWEDG +T VPE ELPL LP   DI+PSGTGESPLAN+TDW++V   +G K
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  482  GKRETNTMPQWAGSSWYFLRFVDPHNKEALADYDKLKQWMPVDLYIGGAEHAVLHLLYAR  541
            G+RETNTMPQWAGSSWY+LR++DPHN E LAD + LKQW+PVD+Y+GGAEHAVLHLLYAR
Sbjct  484  GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYAR  543

Query  542  FWNLFLYDIGAIPNKEPFQRLFNQGMILG-------------------------------  570
            FW+  LYD+G +P KEPFQ+LFNQGMILG                               
Sbjct  544  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEE  603

Query  571  --DNHEKMSKSKGNVVNPDDVVDEYGADTLRLYEMFMGPLDAGIAWSTDGLAGARKFLDR  628
              +   KMSKS  NVVNPDDVV++YGADTLR+YEMFMGPLDA+IAWS +GL G+RKFLDR
Sbjct  604  LEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR  663

Query  629  VWSAFIDDEGKLRDRITTINDGRLDKVYNETVKKVTEDYEALHFNTAIAQMMVFINSARK  688
            V   +   E      IT  N G LDKVYNETVK VTE+ + + FNTAIAQ+MVF+N+A K
Sbjct  664  VYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANK  717

Query  689  DDDLPLEYVEGFVKMLAPIAPHLMEEIWQRL-GHDHSLTYAPWPSYDESKLKTDTYDMMV  747
            +D L  +Y  GFV+++AP+APHL EE+WQ L + ++S++Y PWPSYDESKL  +  +++V
Sbjct  718  EDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVV  777

Query  748  QVNGKLRGSITASVDETDDEIKQAALANENVQKYTTGKD  786
            Q++GK+++ +  + D + +E+++ ALANE+VQ   +GKD
Sbjct  778  QIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKD  816

351) leuS in NC_013199


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  878 bits (3325),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 529/819 (65%), Positives = 655/819 (80%), Gaps = 41/819 (5%)

Query  3    YDHHEIDKKWQRYWAEHNEFNTTTDPKKPNYYALDMFPYPSGQGLHVGHPEGYTATDIVA  62
            YDH  I+ KWQ +WA+++ F+T TD+ KP++YALDMFPYPSG GLHVGHPEGYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMKRMQGFNVLHPMGWDAFGLPAEQYALNTGHNPRTFTKQNIETFKRQINSLGFSYDWNR  122
            R KR QG NVLHPMGWDAFGLPAEQYA++TG++P  FT +NI  FKRQIN+LGFSYDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EINTTDPNYYKWTQWIFEQLYKHGLAYEAEVPVNWSPDLGTVVANEEVI-DGKTERGGFP  181
            E+NTTDPNYYKWTQWIF +LY  GLAYEAEVPVNW  +LGT +ANEEV+ DG +ERGG+P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VVRKPMRQWMLKITAYadklladlddldWPESIKQMQRNWIGKSTGAQITFTVTDTQEKF  241
            VVRKPMRQWMLKITAYA++LL DL+++DWPESIK+MQRNWIGKSTGA++TF V DT+  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  DVFTTRPDTLFGATYVVMAPEHDLVEKITTPEQQAVVDAYIEEAAHKSDLDRTALDKEKT  301
             VFTTRPDTLFGATY V+APEH LV+ ITT++Q   V  Y  +A+ KSDL RT L KEKT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVWTGAYATNPVNGEKLPIWISDYVLATYGTGAIMAVPAHDDRDYAFAKKFGIEIKPVIE  361
            GVWTG+YA NPVNG  +P+WI+DYVLA+YGTGAIMAVPAHD+RD  FAK+F ++I PV+E
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGNIDEAAYTGDGVHINSGFLDGLNEQDAIDRMIAWLEDKGIGQEKVNYKLRDWVFSRQR  421
            GGN++EAA+T DG+HINS+FLDGL+   AI +M+ WLE  G+G+E+V Y+LRDW+FSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPVIHWEDGettlvpedelpltlpeevdIKPSGTGESPLANLTDWVNVVDKNGRK  481
            YWGEPIP+IHWEDG +T VPE ELPL LP   DI+PSGTGESPLAN+TDW++V   +G K
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  482  GKRETNTMPQWAGSSWYFLRFVDPHNKEALADYDKLKQWMPVDLYIGGAEHAVLHLLYAR  541
            G+RETNTMPQWAGSSWY+LR++DPHN E LAD + LKQW+PVD+Y+GGAEHAVLHLLYAR
Sbjct  484  GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYAR  543

Query  542  FWNLFLYDIGAIPNKEPFQRLFNQGMILG-------------------------------  570
            FW+  LYD+G +P KEPFQ+LFNQGMILG                               
Sbjct  544  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEE  603

Query  571  --DNHEKMSKSKGNVVNPDDVVDEYGADTLRLYEMFMGPLDAGIAWSTDGLAGARKFLDR  628
              +   KMSKS  NVVNPDDVV++YGADTLR+YEMFMGPLDA+IAWS +GL G+RKFLDR
Sbjct  604  LEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR  663

Query  629  VWSAFIDDEGKLRDRITTINDGRLDKVYNETVKKVTEDYEALHFNTAIAQMMVFINSARK  688
            V   +   E      IT  N G LDKVYNETVK VTE+ + + FNTAIAQ+MVF+N+A K
Sbjct  664  VYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANK  717

Query  689  DDDLPLEYVEGFVKMLAPIAPHLMEEIWQRL-GHDHSLTYAPWPSYDESKLKTDTYDMMV  747
            +D L  +Y  GFV+++AP+APHL EE+WQ L + ++S++Y PWPSYDESKL  +  +++V
Sbjct  718  EDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVV  777

Query  748  QVNGKLRGSITASVDETDDEIKQAALANENVQKYTTGKD  786
            Q++GK+++ +  + D + +E+++ ALANE+VQ   +GKD
Sbjct  778  QIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKD  816

352) LOCK900_0812 in NC_021723


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  878 bits (3325),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 530/819 (65%), Positives = 655/819 (80%), Gaps = 41/819 (5%)

Query  3    YDHHEIDKKWQRYWAEHNEFNTTTDPKKPNYYALDMFPYPSGQGLHVGHPEGYTATDIVA  62
            YDH  I+ KWQ +WA+++ F+T TD+ KP++YALDMFPYPSG GLHVGHPEGYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMKRMQGFNVLHPMGWDAFGLPAEQYALNTGHNPRTFTKQNIETFKRQINSLGFSYDWNR  122
            R KR QG NVLHPMGWDAFGLPAEQYA++TG++P  FT +NI  FKRQIN+LGFSYDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EINTTDPNYYKWTQWIFEQLYKHGLAYEAEVPVNWSPDLGTVVANEEVI-DGKTERGGFP  181
            E+NTTDPNYYKWTQWIF +LY  GLAYEAEVPVNW  +LGT +ANEEV+ DG +ERGG+P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VVRKPMRQWMLKITAYadklladlddldWPESIKQMQRNWIGKSTGAQITFTVTDTQEKF  241
            VVRKPMRQWMLKITAYA++LL DL+++DWPESIK+MQRNWIGKSTGA++TF V DT+  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  DVFTTRPDTLFGATYVVMAPEHDLVEKITTPEQQAVVDAYIEEAAHKSDLDRTALDKEKT  301
             VFTTRPDTLFGATY V+APEH LV+ ITT++Q   V  Y  +A+ KSDL RT L KEKT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVWTGAYATNPVNGEKLPIWISDYVLATYGTGAIMAVPAHDDRDYAFAKKFGIEIKPVIE  361
            GVWTG+YA NPVNG  +P+WI+DYVLA+YGTGAIMAVPAHD+RD  FAK+F ++I PV+E
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGNIDEAAYTGDGVHINSGFLDGLNEQDAIDRMIAWLEDKGIGQEKVNYKLRDWVFSRQR  421
            GGN++EAA+T DG+HINS+FLDGL+   AI +M+ WLE  G+G+E+V Y+LRDW+FSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPVIHWEDGettlvpedelpltlpeevdIKPSGTGESPLANLTDWVNVVDKNGRK  481
            YWGEPIP+IHWEDG +T VPE ELPL LP   DI+PSGTGESPLAN+TDW++V   +G K
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  482  GKRETNTMPQWAGSSWYFLRFVDPHNKEALADYDKLKQWMPVDLYIGGAEHAVLHLLYAR  541
            G+RETNTMPQWAGSSWY+LR++DPHN E LAD + LKQW+PVD+Y+GGAEHAVLHLLYAR
Sbjct  484  GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYAR  543

Query  542  FWNLFLYDIGAIPNKEPFQRLFNQGMILG-------------------------------  570
            FW+  LYD+G +P KEPFQ+LFNQGMILG                               
Sbjct  544  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEE  603

Query  571  --DNHEKMSKSKGNVVNPDDVVDEYGADTLRLYEMFMGPLDAGIAWSTDGLAGARKFLDR  628
              +   KMSKS  NVVNPDDVV++YGADTLR+YEMFMGPLDA+IAWS +GL G+RKFLDR
Sbjct  604  LEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR  663

Query  629  VWSAFIDDEGKLRDRITTINDGRLDKVYNETVKKVTEDYEALHFNTAIAQMMVFINSARK  688
            V   +   E      IT  N G LDKVYNETVK VTE+ + + FNTAIAQ+MVF+N+A K
Sbjct  664  VYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANK  717

Query  689  DDDLPLEYVEGFVKMLAPIAPHLMEEIWQRL-GHDHSLTYAPWPSYDESKLKTDTYDMMV  747
            +D L  +Y  GFV+++AP+APHL EE+WQ L + ++S++Y PWPSYDESKL  +  +++V
Sbjct  718  EDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVV  777

Query  748  QVNGKLRGSITASVDETDDEIKQAALANENVQKFTAGKD  786
            Q++GK+++ +  + D + +E+++ ALANE+VQ   AGKD
Sbjct  778  QIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKD  816

353) LOCK908_0914 in NC_021725


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  878 bits (3325),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 529/819 (65%), Positives = 655/819 (80%), Gaps = 41/819 (5%)

Query  3    YDHHEIDKKWQRYWAEHNEFNTTTDPKKPNYYALDMFPYPSGQGLHVGHPEGYTATDIVA  62
            YDH  I+ KWQ +WA+++ F+T TD+ KP++YALDMFPYPSG GLHVGHPEGYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMKRMQGFNVLHPMGWDAFGLPAEQYALNTGHNPRTFTKQNIETFKRQINSLGFSYDWNR  122
            R KR QG NVLHPMGWDAFGLPAEQYA++TG++P  FT +NI  FKRQIN+LGFSYDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EINTTDPNYYKWTQWIFEQLYKHGLAYEAEVPVNWSPDLGTVVANEEVI-DGKTERGGFP  181
            E+NTTDPNYYKWTQWIF +LY  GLAYEAEVPVNW  +LGT +ANEEV+ DG +ERGG+P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VVRKPMRQWMLKITAYadklladlddldWPESIKQMQRNWIGKSTGAQITFTVTDTQEKF  241
            VVRKPMRQWMLKITAYA++LL DL+++DWPESIK+MQRNWIGKSTGA++TF V DT+  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  DVFTTRPDTLFGATYVVMAPEHDLVEKITTPEQQAVVDAYIEEAAHKSDLDRTALDKEKT  301
             VFTTRPDTLFGATY V+APEH LV+ ITT++Q   V  Y  +A+ KSDL RT L KEKT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVWTGAYATNPVNGEKLPIWISDYVLATYGTGAIMAVPAHDDRDYAFAKKFGIEIKPVIE  361
            GVWTG+YA NPVNG  +P+WI+DYVLA+YGTGAIMAVPAHD+RD  FAK+F ++I PV+E
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGNIDEAAYTGDGVHINSGFLDGLNEQDAIDRMIAWLEDKGIGQEKVNYKLRDWVFSRQR  421
            GGN++EAA+T DG+HINS+FLDGL+   AI +M+ WLE  G+G+E+V Y+LRDW+FSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPVIHWEDGettlvpedelpltlpeevdIKPSGTGESPLANLTDWVNVVDKNGRK  481
            YWGEPIP+IHWEDG +T VPE ELPL LP   DI+PSGTGESPLAN+TDW++V   +G K
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  482  GKRETNTMPQWAGSSWYFLRFVDPHNKEALADYDKLKQWMPVDLYIGGAEHAVLHLLYAR  541
            G+RETNTMPQWAGSSWY+LR++DPHN E LAD + LKQW+PVD+Y+GGAEHAVLHLLYAR
Sbjct  484  GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYAR  543

Query  542  FWNLFLYDIGAIPNKEPFQRLFNQGMILG-------------------------------  570
            FW+  LYD+G +P KEPFQ+LFNQGMILG                               
Sbjct  544  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEE  603

Query  571  --DNHEKMSKSKGNVVNPDDVVDEYGADTLRLYEMFMGPLDAGIAWSTDGLAGARKFLDR  628
              +   KMSKS  NVVNPDDVV++YGADTLR+YEMFMGPLDA+IAWS +GL G+RKFLDR
Sbjct  604  LEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR  663

Query  629  VWSAFIDDEGKLRDRITTINDGRLDKVYNETVKKVTEDYEALHFNTAIAQMMVFINSARK  688
            V   +   E      IT  N G LDKVYNETVK VTE+ + + FNTAIAQ+MVF+N+A K
Sbjct  664  VYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANK  717

Query  689  DDDLPLEYVEGFVKMLAPIAPHLMEEIWQRL-GHDHSLTYAPWPSYDESKLKTDTYDMMV  747
            +D L  +Y  GFV+++AP+APHL EE+WQ L + ++S++Y PWPSYDESKL  +  +++V
Sbjct  718  EDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVV  777

Query  748  QVNGKLRGSITASVDETDDEIKQAALANENVQKYTTGKD  786
            Q++GK+++ +  + D + +E+++ ALANE+VQ   +GKD
Sbjct  778  QIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKD  816

354) leuS in NC_021554


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  878 bits (3325),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 544/837 (65%), Positives = 674/837 (81%), Gaps = 42/837 (5%)

Query  3    YNHNQIEKKWQDYWDENKTFKTNDNLGQKKFYALDMFPYPSGAGLHVGHPEGYTATDIIS  62
            Y+H  IE KWQ +W +N TFKT  + ++ KFYALDMFPYPSGAGLHVGHPEGYTATDI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRMQGYNVLHPMGWDAFGLPAEQYALDTGNDPREFTKKNIQTFKRQIKELGFSYDWDR  122
            R+KR QG NVLHPMGWDAFGLPAEQYA+DTGNDP EFT  NI  FKRQI+ LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVNTTDPEYYKWTQWIFIQLYNKGLAYVDEVAVNWCPALGTVLSNEEVI-DGVSERGGHP  181
            EVNTTDP+YYKWTQWIF +LY+KGLAY  EV+VNW   LGT ++NEEV+ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VYRKPMKQWVLKITEYadqlladlddldWPESLKDMQRNWIGRSEGAKVSFDVDNAEGKV  241
            V RKPM+QW+LKIT YA++LL DL+++DWPES+KDMQRNWIG+S GA+V+F V +++   
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  EVFTTRPDTIYGASFLVLSPEHALVDSITTDEYKDQVKAYQTEASKKSDLERTDLAKDKS  301
             VFTTRPDT++GA++ VL+PEHALVD+ITT +  + V  Y+ +AS KSDL RTDLAK+K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAINPLSGEKVQIWIADYVLSTYGTGAIMAVPAHDDRDYEFAKKFDLPiievie  361
            GV TG+YAINP++G  + +WIADYVL++YGTGAIMAVPAHD+RD EFAK+F+L II V+E
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  ggnveeAAYTGEGKHINSGELNGLENEAAITKAIQLLEQKGAGEKKVNYKLRDWLFSRQR  421
            GGNVEEAA+T +G HINS+ L+GL++ +AI+K ++ LE  G G+ +V Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPVIHWEDGTMTTVpeeelplllpeTDEIKPSGTGESPLANIDSFVNVVDEKTGM  481
            YWGEPIP+IHWEDGT T+VPE ELPL+LP T +I+PSGTGESPLAN+   ++V  E  G+
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED-GV  482

Query  482  KGRRETNTMPQWAGSCWYYLRYIDPKNENMLADPEKLKHWLPVDLYIGGVEHAVLHLLYA  541
            KGRRETNTMPQWAGS WYYLRYIDP N + LAD E LK+WLPVD+Y+GG EHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKVLYDLGIVPTKEPFQKLFNQGMILG------------------------------  571
            RFWHKVLYDLG+VPTKEPFQKLFNQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---EGNEKMSKSKGNVINPDEIVQSHGADTLRLYEMFMGPLDAAIAWSEKGLDGSRRFLD  628
               ++  KMSKS  NV+NPD++V+  GADTLR+YEMFMGPLDA+IAWSE GL+GSR+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RVWRLMVNEDGTLSSKIVTSNNKSLDKVYNQTVKKVTEDFETLGFNTAISQLMVFINECY  688
            RV RL+   +      I   N+ +LDKVYN+TVK VTE+ + + FNTAI+QLMVF+N   
Sbjct  663  RVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  689  KVDEVYKPYIEGFVKMLAPIAPHIGEELWSKL-GHEESITYQPWPTYDEALLVDDEVEIV  747
            K D ++  Y  GFV+++AP+APH+GEELW  L +  ESI+Y PWP+YDE+ LV+++VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  748  VQVNGKLRAKIKIAKDTSKEEMQEIALSNDNVKASIEGKDIMKVIAVPQKLVNIVAK  804
            VQ++GK++AK+ +AKD S+EE+QE+AL+N++V+A I GKDI+KVIAVP+KLVNIV K
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

355) Bsel_1235 in NC_014219


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  878 bits (3327),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 533/838 (64%), Positives = 660/838 (79%), Gaps = 43/838 (5%)

Query  3    FDHQEIEKKWQHVWesektfkttedtdkekfYALDMFPYPSGAGLHVGHPEGYTATDILS  62
            +DH  IE KWQ  W  + TFKT  D+ K KFYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMKRMQGYNVLHPMGWDAFGLPAEQYALDTGKHPREFTEKNIETFRRQIKSLGFSYDWDR  122
            R KR QG NVLHPMGWDAFGLPAEQYA+DTG++P EFT  NI  F+RQI++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EINTTDEKYYKWTQWIFIQLYNKGLAYMDEVAVNWCPALGTVLANEEVI-EGKSERGGHP  181
            E+NTTD +YYKWTQWIF +LY+KGLAY  EV+VNW   LGT +ANEEV+ +G SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VEKRPMKQWMLKITEYGdrlledledldWPESIKDMQRNWIGRSEGADVTFTFEKTGEEV  241
            V ++PM+QWMLKIT Y++RLLEDLE++DWPESIKDMQRNWIG+S GA+VTF    T+ + 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  TVFTTRPDTLYGATYLVLAPEHKAVQSVTTPEQKEEVEAYIKKVTHKSDLERTELSKEKT  301
            TVFTTRPDTL+GATY VLAPEH  V+++TT++Q E V  Y ++ + KSDL RT+L+KEKT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGGYAIHPVSGEQVPVWIADYVLISYGSGAIMAVPAHDERDYEFAKTFDLPIREVVE  361
            GV TG+YAI+PV+G ++PVWIADYVL SYG+GAIMAVPAHDERD EFAK F+L I  V+E
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGDVSKEAYAGDGAHINSDFLNGLDNSEAIAKMIDWLEQEGKGERKVTYRLRDWLFSRQR  421
            GG+V   A++ DG HINSDFL+GLD++ AIAKM++WLE EG G+ +VTYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPMIHWEDGSLEPVPEDELPLTLPDMDEFKPSGTGESPLANNEEWLHVTDPSTGR  481
            YWGEPIP+IHWEDG+  +VPE ELPL LP   +++PSGTGESPLAN  +WL+VT    G 
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT-REDGV  482

Query  482  KGRRETNTMPQWAGSCWYYLRYIDPDNDQALADPSKLREWLPVDIYIGGAEHAVLHLLYA  541
            KGRRETNTMPQWAGS WYYLRYIDP+N + LAD   L++WLPVDIY+GGAEHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKVLYDLGVVPTKEPFQKLYNQGMILG------------------------------  571
            RFWHKVLYDLGVVPTKEPFQKL+NQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---ENNEKMSKSKGNVVNPDDILQSHGADTLRLYEMFMGPLDAAIAWSDNGLDGARRFLD  628
               +   KMSKS  NVVNPDD+++  GADTLR+YEMFMGPLDA+IAWS++GL+G+R+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RVWRLFVKDDGALSPQIQDAQGSETMTKVYHQTVKKVTEDFKELRFNTGISQLMVFVNEA  688
            RV RL+   + +        + S ++ KVY++TVK VTE+  +++FNT+I+QLMVFVN A
Sbjct  663  RVYRLITTKEIT-------EENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAA  715

Query  689  YKQEMLSKSHLEGFLKLLSPVAPHIAEELWSRL-GHGETISYSTWPVYDEAMLEDDTVLV  747
             K++ L      GF++L++P APH++EELW  L + GE+ISY  WP YDE+ L ++ V +
Sbjct  716  NKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEI  775

Query  748  VVQINGKLKSKLDLPKGTSKEDMEAAALADDKIKQAIDGKTVRKVIAVPDKLVNIVAN  805
            VVQI+GK+K+KL ++K+ S+E+++  ALA++K++  I GK + KVIAVP+KLVNIV +
Sbjct  776  VVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

356) leuS in NC_017763


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  877 bits (3323),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 546/837 (66%), Positives = 674/837 (81%), Gaps = 42/837 (5%)

Query  3    YNHNQIEKKWQDYWDENKTFKTNDNLGQKKFYALDMFPYPSGAGLHVGHPEGYTATDIIS  62
            Y+H  IE KWQ +W +N TFKT  + ++ KFYALDMFPYPSGAGLHVGHPEGYTATDI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRMQGYNVLHPMGWDAFGLPAEQYALDTGNDPREFTKKNIQTFKRQIKELGFSYDWDR  122
            R+KR QG NVLHPMGWDAFGLPAEQYA+DTGNDP EFT  NI  FKRQI+ LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVNTTDPEYYKWTQWIFIQLYNKGLAYVDEVAVNWCPALGTVLSNEEVI-DGVSERGGHP  181
            EVNTTDP+YYKWTQWIF +LY+KGLAY  EV+VNW   LGT ++NEEV+ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VYRKPMKQWVLKITEYadqlladlddldWPESLKDMQRNWIGRSEGAKVSFDVDNTEGKV  241
            V RKPM+QW+LKIT YA++LL DL+++DWPES+KDMQRNWIG+S GA+V+F V +T+   
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  EVFTTRPDTIYGASFLVLSPEHALVNSITTDEYKEKVKAYQTEASKKSDLERTDLAKDKS  301
             VFTTRPDT++GA++ VL+PEHALV++ITT +  E V  Y+ +AS KSDL RTDLAK+K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAINPLSGEKVQIWIADYVLSTYGTGAIMAVPAHDDRDYEFAKKFDLPiievie  361
            GV TG+YAINP++G  + +WIADYVL++YGTGAIMAVPAHD+RD EFAK+F+L II V+E
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  ggnveeAAYTGEGKHINSGELDGLENEAAITKAIQLLEQKGAGEKKVNYKLRDWLFSRQR  421
            GGNVEEAA+T +G HINS+ LDGL++ +AI+K ++ LE  G G+ +V Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPVIHWEDGTMTTVpeeelplllpeTDEIKPSGTGESPLANIDSFVNVVDEKTGM  481
            YWGEPIP+IHWEDGT T+VPE ELPL+LP T +I+PSGTGESPLAN+   ++V  E  G+
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED-GV  482

Query  482  KGRRETNTMPQWAGSCWYYLRYIDPKNENMLADPEKLKHWLPVDLYIGGVEHAVLHLLYA  541
            KGRRETNTMPQWAGS WYYLRYIDP N + LAD E LK+WLPVD+Y+GG EHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKVLYDLGIVPTKEPFQKLFNQGMILG------------------------------  571
            RFWHKVLYDLG+VPTKEPFQKLFNQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---EGNEKMSKSKGNVINPDDIVQSHGADTLRLYEMFMGPLDAAIAWSEKGLDGSRRFLD  628
               ++  KMSKS  NV+NPDD+V+  GADTLR+YEMFMGPLDA+IAWSE GL+GSR+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RVWRLMVNEDGTLSSKIVTTNNKSLDKVYNQTVKKVTEDFETLGFNTAISQLMVFINECY  688
            RV RL+   +      I   N+ +LDKVYN+TVK VTE+ + + FNTAI+QLMVF+N   
Sbjct  663  RVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  689  KVDEVYKPYIEGFVKMLAPIAPHIGEELWSKL-GHEESITYQPWPTFDEALLVDDEVEIV  747
            K D ++  Y  GFV+++AP+APH+GEELW  L +  ESI+Y PWP++DE+ LV+++VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  748  VQVNGKLRAKIKIAKDTSKEEMQEIALSNDNVKASIEGKDIMKVIAVPQKLVNIVAK  804
            VQ++GK++AK+ +AKD S+EE+QE+AL+N++V+A I GKDI+KVIAVP+KLVNIV K
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

357) leuS in NC_007622


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  877 bits (3323),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 547/837 (66%), Positives = 674/837 (81%), Gaps = 42/837 (5%)

Query  3    YNHNQIEKKWQDYWDENKTFKTNDNLGQKKFYALDMFPYPSGAGLHVGHPEGYTATDIIS  62
            Y+H  IE KWQ +W +N TFKT  + ++ KFYALDMFPYPSGAGLHVGHPEGYTATDI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRMQGYNVLHPMGWDAFGLPAEQYALDTGNDPREFTKKNIQTFKRQIKELGFSYDWDR  122
            R+KR QG NVLHPMGWDAFGLPAEQYA+DTGNDP EFT  NI  FKRQI+ LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVNTTDPEYYKWTQWIFIQLYNKGLAYVDEVAVNWCPALGTVLSNEEVI-DGVSERGGHP  181
            EVNTTDP+YYKWTQWIF +LY+KGLAY  EV+VNW   LGT ++NEEV+ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VYRKPMKQWVLKITEYadqlladlddldWPESLKDMQRNWIGRSEGAKVSFDVDNTEGKV  241
            V RKPM+QW+LKIT YA++LL DL+++DWPES+KDMQRNWIG+S GA+V+F V +T+   
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  EVFTTRPDTIYGASFLVLSPEHALVNSITTDEYKEKVKAYQTEASKKSDLERTDLAKDKS  301
             VFTTRPDT++GA++ VL+PEHALV++ITT +  E V  Y+ +AS KSDL RTDLAK+K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAINPLSGEKVQIWIADYVLSTYGTGAIMAVPAHDDRDYEFAKKFDLLiievie  361
            GV TG+YAINP++G  + +WIADYVL++YGTGAIMAVPAHD+RD EFAK+F+L II V+E
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  ggnveeAAYTGEGKHINSGELDGLENEAAITKAIQLLEQKGAGEKKVNYKLRDWLFSRQR  421
            GGNVEEAA+T +G HINS+ LDGL++ +AI+K ++ LE  G G+ +V Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPVIHWEDGTMTTVpeeelplllpeTDEIKPSGTGESPLANIDSFVNVVDEKTGM  481
            YWGEPIP+IHWEDGT T+VPE ELPL+LP T +I+PSGTGESPLAN+   ++V  E  G+
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED-GV  482

Query  482  KGRRETNTMPQWAGSCWYYLRYIDPKNENMLADPEKLKHWLPVDLYIGGVEHAVLHLLYA  541
            KGRRETNTMPQWAGS WYYLRYIDP N + LAD E LK+WLPVD+Y+GG EHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKVLYDLGIVPTKEPFQKLFNQGMILG------------------------------  571
            RFWHKVLYDLG+VPTKEPFQKLFNQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---EGNEKMSKSKGNVINPDDIVQSHGADTLRLYEMFMGPLDAAIAWSEKGLDGSRRFLD  628
               ++  KMSKS  NV+NPDD+V+  GADTLR+YEMFMGPLDA+IAWSE GL+GSR+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RVWRLIVNEDGTLSSKIVTTNNKSLDKVYNQTVKKVTDDFETLGFNTAISQLMVFINECY  688
            RV RLI   +      I   N+ +LDKVYN+TVK VT++ + + FNTAI+QLMVF+N   
Sbjct  663  RVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  689  KVDEVYKPYIEGFVKMLAPIAPHIGEELWSKL-GHEESITYQPWPTYDEALLVDDEVEIV  747
            K D ++  Y  GFV+++AP+APH+GEELW  L +  ESI+Y PWP+YDE+ LV+++VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  748  VQVNGKLRAKIKIAKDTSKEEMQEIALSNDNVKASIEGKDIMKVIAVPQKLVNIVAK  804
            VQ++GK++AK+ +AKD S+EE+QE+AL+N++V+A I GKDI+KVIAVP+KLVNIV K
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

358) LRHM_0806 in NC_017482


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  877 bits (3321),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 528/819 (65%), Positives = 654/819 (80%), Gaps = 41/819 (5%)

Query  3    YDHHEIDKKWQRYWAEHNEFNTTTDPKKPNYYALDMFPYPSGQGLHVGHPEGYTATDIVA  62
            YDH  I+ KWQ +WA+++ F+T TD+ KP++YALDMFPYPSG GLHVGHPEGYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMKRMQGFNVLHPMGWDAFGLPAEQYALNTGHNPRTFTKQNIETFKRQINSLGFSYDWNR  122
            R KR QG NVLHPMGWDAFGLPAEQYA++TG++P  FT +NI  FKRQIN+LGFSYDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EINTTDPNYYKWTQWIFEQLYKHGLAYEAEVPVNWSPDLGTVVANEEVI-DGKTERGGFP  181
            E+NTTDPNYYKWTQWIF +LY  GLAYEAEVPVNW  +LGT +ANEEV+ DG +ERGG+P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VVRKPMRQWMLKITAYadklladlddldWPESIKQMQRNWIGKSTGAQITFTVTDTQEKF  241
            VVRKPMRQWMLKITAYA++LL DL+++DWPESIK+MQRNWIGKSTGA++TF V DT+  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  DVFTTRPDTLFGATYVVMAPEHDLVEKITTPEQQAVVDAYIEEAAHKSDLDRTALDKEKT  301
             VFTTRPDTLFGATY V+APEH LV+ ITT++Q   V  Y  +A+ KSDL RT L KEKT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVWTGAYATNPVNGEKLPIWISDYVLATYGTGAIMAVPAHDDRDYAFAKKFGIEIKPVIE  361
            GVWTG+YA NPVNG  +P+WI+DYVLA+YGTGAIMAVPAHD+RD  FAK+F ++I PV+E
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGNIDEAAYTGDGVHINSGFLDGLNEQDAIDRMIAWLEDKGIGQAKVNYKLRDWVFSRQR  421
            GGN++EAA+T DG+HINS+FLDGL+   AI +M+ WLE  G+G+ +V Y+LRDW+FSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPVIHWEDGettlvpedelpltlpeevdIKPSGTGESPLANLTDWVNVVDKNGRK  481
            YWGEPIP+IHWEDG +T VPE ELPL LP   DI+PSGTGESPLAN+TDW++V   +G K
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  482  GKRETNTMPQWAGSSWYFLRFVDPHNKEALADYDKLKQWMPVDLYIGGAEHAVLHLLYAR  541
            G+RETNTMPQWAGSSWY+LR++DPHN E LAD + LKQW+PVD+Y+GGAEHAVLHLLYAR
Sbjct  484  GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYAR  543

Query  542  FWNLFLYDIGAIPNKEPFQRLFNQGMILG-------------------------------  570
            FW+  LYD+G +P KEPFQ+LFNQGMILG                               
Sbjct  544  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEE  603

Query  571  --DNHEKMSKSKGNVVNPDDVVDEYGADTLRLYEMFMGPLDAGIAWSTDGLAGARKFLDR  628
              +   KMSKS  NVVNPDDVV++YGADTLR+YEMFMGPLDA+IAWS +GL G+RKFLDR
Sbjct  604  LEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR  663

Query  629  VWSAFIDDEGKLRDRITTINDGRLDKVYNETVKKVTEDYEALHFNTAIAQMMVFINSARK  688
            V   +   E      IT  N G LDKVYNETVK VTE+ + + FNTAIAQ+MVF+N+A K
Sbjct  664  VYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANK  717

Query  689  DDDLPLEYVEGFVKMLAPIAPHLMEEIWQRL-GHDHSLTYAPWPSYDESKLKTDTYDMMV  747
            +D L  +Y  GFV+++AP+APHL EE+WQ L + ++S++Y PWPSYDESKL  +  +++V
Sbjct  718  EDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVV  777

Query  748  QVNGKLRGSITASVDETDDEIKQAALANENVQKYTTGKD  786
            Q++GK+++ +  + D + +E+++ ALANE+VQ   +GKD
Sbjct  778  QIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKD  816

359) leuS in NC_013198


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  877 bits (3321),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 528/819 (65%), Positives = 654/819 (80%), Gaps = 41/819 (5%)

Query  3    YDHHEIDKKWQRYWAEHNEFNTTTDPKKPNYYALDMFPYPSGQGLHVGHPEGYTATDIVA  62
            YDH  I+ KWQ +WA+++ F+T TD+ KP++YALDMFPYPSG GLHVGHPEGYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMKRMQGFNVLHPMGWDAFGLPAEQYALNTGHNPRTFTKQNIETFKRQINSLGFSYDWNR  122
            R KR QG NVLHPMGWDAFGLPAEQYA++TG++P  FT +NI  FKRQIN+LGFSYDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EINTTDPNYYKWTQWIFEQLYKHGLAYEAEVPVNWSPDLGTVVANEEVI-DGKTERGGFP  181
            E+NTTDPNYYKWTQWIF +LY  GLAYEAEVPVNW  +LGT +ANEEV+ DG +ERGG+P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VVRKPMRQWMLKITAYadklladlddldWPESIKQMQRNWIGKSTGAQITFTVTDTQEKF  241
            VVRKPMRQWMLKITAYA++LL DL+++DWPESIK+MQRNWIGKSTGA++TF V DT+  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  DVFTTRPDTLFGATYVVMAPEHDLVEKITTPEQQAVVDAYIEEAAHKSDLDRTALDKEKT  301
             VFTTRPDTLFGATY V+APEH LV+ ITT++Q   V  Y  +A+ KSDL RT L KEKT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVWTGAYATNPVNGEKLPIWISDYVLATYGTGAIMAVPAHDDRDYAFAKKFGIEIKPVIE  361
            GVWTG+YA NPVNG  +P+WI+DYVLA+YGTGAIMAVPAHD+RD  FAK+F ++I PV+E
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGNIDEAAYTGDGVHINSGFLDGLNEQDAIDRMIAWLEDKGIGQAKVNYKLRDWVFSRQR  421
            GGN++EAA+T DG+HINS+FLDGL+   AI +M+ WLE  G+G+ +V Y+LRDW+FSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPVIHWEDGettlvpedelpltlpeevdIKPSGTGESPLANLTDWVNVVDKNGRK  481
            YWGEPIP+IHWEDG +T VPE ELPL LP   DI+PSGTGESPLAN+TDW++V   +G K
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  482  GKRETNTMPQWAGSSWYFLRFVDPHNKEALADYDKLKQWMPVDLYIGGAEHAVLHLLYAR  541
            G+RETNTMPQWAGSSWY+LR++DPHN E LAD + LKQW+PVD+Y+GGAEHAVLHLLYAR
Sbjct  484  GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYAR  543

Query  542  FWNLFLYDIGAIPNKEPFQRLFNQGMILG-------------------------------  570
            FW+  LYD+G +P KEPFQ+LFNQGMILG                               
Sbjct  544  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEE  603

Query  571  --DNHEKMSKSKGNVVNPDDVVDEYGADTLRLYEMFMGPLDAGIAWSTDGLAGARKFLDR  628
              +   KMSKS  NVVNPDDVV++YGADTLR+YEMFMGPLDA+IAWS +GL G+RKFLDR
Sbjct  604  LEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR  663

Query  629  VWSAFIDDEGKLRDRITTINDGRLDKVYNETVKKVTEDYEALHFNTAIAQMMVFINSARK  688
            V   +   E      IT  N G LDKVYNETVK VTE+ + + FNTAIAQ+MVF+N+A K
Sbjct  664  VYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANK  717

Query  689  DDDLPLEYVEGFVKMLAPIAPHLMEEIWQRL-GHDHSLTYAPWPSYDESKLKTDTYDMMV  747
            +D L  +Y  GFV+++AP+APHL EE+WQ L + ++S++Y PWPSYDESKL  +  +++V
Sbjct  718  EDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVV  777

Query  748  QVNGKLRGSITASVDETDDEIKQAALANENVQKYTTGKD  786
            Q++GK+++ +  + D + +E+++ ALANE+VQ   +GKD
Sbjct  778  QIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKD  816

360) leuS in NC_021670


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  876 bits (3316),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 545/837 (66%), Positives = 673/837 (81%), Gaps = 42/837 (5%)

Query  4    YNHNQIEKKWQDYWDENKTFKTNDNLGQKKFYALDMFPYPSGAGLHVGHPEGYTATDIIS  63
            Y+H  IE KWQ +W +N TFKT  + ++ KFYALDMFPYPSGAGLHVGHPEGYTATDI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYKRMQGYNVLHPMGWDAFGLPAEQYALDTGNDPREFTKKNIQTFKRQIKELGFSYDWDR  123
            R+KR QG NVLHPMGWDAFGLPAEQYA+DTGNDP EFT  NI  FKRQI+ LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVNTTDPEYYKWTQWIFIQLYNKGLAYVDEVAVNWCPALGTVLSNEEVI-DGVSERGGHP  182
            EVNTTDP+YYKWTQWIF +LY+KGLAY  EV+VNW   LGT ++NEEV+ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VYRKPMKQWVLKITEYadqlladlddldWPESLKDMQRNWIGRSEGAKVSFDVDNTEGKV  242
            V RKPM+QW+LKIT YA++LL DL+++DWPES+KDMQRNWIG+S GA+V+F V +T+   
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  243  EVFTTRPDTIYGASFLVLSPEHALVNSITTDEYKEKVKAYQTEASKKSDLERTDLAKDKS  302
             VFTTRPDT++GA++ VL+PEHALV++ITT +  E V  Y+ +AS KSDL RTDLAK+K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  303  GVFTGAYATNPLSGEKVQIWIADYVLSTYGTGAIMAVPAHDDRDYEFAKKFDLPiievie  362
            GV TG+YA NP++G  + +WIADYVL++YGTGAIMAVPAHD+RD EFAK+F+L II V+E
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  363  ggnveeAAYTGEGKHINSGELDGLENEAAITKAIQLLEQKGAGEKKVNYKLRDWLFSRQR  422
            GGNVEEAA+T +G HINS+ LDGL++ +AI+K ++ LE  G G+ +V Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  423  YWGEPIPVIHWEDGTMTTVpeeelplllpeTDEIKPSGTGESPLANIDSFVNVVDEKTGM  482
            YWGEPIP+IHWEDGT T+VPE ELPL+LP T +I+PSGTGESPLAN+   ++V  E  G+
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED-GV  482

Query  483  KGRRETNTMPQWAGSCWYYLRYIDPKNENMLADPEKLKHWLPVDLYIGGVEHAVLHLLYA  542
            KGRRETNTMPQWAGS WYYLRYIDP N + LAD E LK+WLPVD+Y+GG EHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  543  RFWHKVLYDLAIVPTKEPFQKLFNQGMILG------------------------------  572
            RFWHKVLYDL++VPTKEPFQKLFNQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  573  ---EGNEKMSKSKGNVINPDDIVQSHGADTLRLYEMFMGPLDAAIAWSEKGLDGSRRFLD  629
               ++  KMSKS  NV+NPDD+V+  GADTLR+YEMFMGPLDA+IAWSE GL+GSR+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  630  RVWRLMVNEDGTLSSKIVTTNNKSLDKVYNQTVKKVTEDFETLGFNTAISQLMVFINECY  689
            RV RL+   +      I   N+ +LDKVYN+TVK VTE+ + + FNTAI+QLMVF+N   
Sbjct  663  RVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  690  KVDEVYKPYIEGFVKMLAPIAPHIGEELWSKL-GHEESITYQPWPTYDEALLVDDEVEIV  748
            K D ++  Y  GFV+++AP+APH+GEELW  L +  ESI+Y PWP+YDE+ LV+++VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  749  VQVNGKLRAKIKIAKDTSKEEMQEIALSNDNVKASIEGKDIMKVIAVPQKLVNIVAK  805
            VQ++GK++AK+ +AKD S+EE+QE+AL+N++V+A I GKDI+KVIAVP+KLVNIV K
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

361) leuS in NC_002951


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  876 bits (3316),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 545/837 (66%), Positives = 673/837 (81%), Gaps = 42/837 (5%)

Query  4    YNHNQIEKKWQDYWDENKTFKTNDNLGQKKFYALDMFPYPSGAGLHVGHPEGYTATDIIS  63
            Y+H  IE KWQ +W +N TFKT  + ++ KFYALDMFPYPSGAGLHVGHPEGYTATDI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYKRMQGYNVLHPMGWDAFGLPAEQYALDTGNDPREFTKKNIQTFKRQIKELGFSYDWDR  123
            R+KR QG NVLHPMGWDAFGLPAEQYA+DTGNDP EFT  NI  FKRQI+ LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVNTTDPEYYKWTQWIFIQLYNKGLAYVDEVAVNWCPALGTVLSNEEVI-DGVSERGGHP  182
            EVNTTDP+YYKWTQWIF +LY+KGLAY  EV+VNW   LGT ++NEEV+ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VYRKPMKQWVLKITEYadqlladlddldWPESLKDMQRNWIGRSEGAKVSFDVDNTEGKV  242
            V RKPM+QW+LKIT YA++LL DL+++DWPES+KDMQRNWIG+S GA+V+F V +T+   
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  243  EVFTTRPDTIYGASFLVLSPEHALVNSITTDEYKEKVKAYQTEASKKSDLERTDLAKDKS  302
             VFTTRPDT++GA++ VL+PEHALV++ITT +  E V  Y+ +AS KSDL RTDLAK+K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  303  GVFTGAYATNPLSGEKVQIWIADYVLSTYGTGAIMAVPAHDDRDYEFAKKFDLPiievie  362
            GV TG+YA NP++G  + +WIADYVL++YGTGAIMAVPAHD+RD EFAK+F+L II V+E
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  363  ggnveeAAYTGEGKHINSGELDGLENEAAITKAIQLLEQKGAGEKKVNYKLRDWLFSRQR  422
            GGNVEEAA+T +G HINS+ LDGL++ +AI+K ++ LE  G G+ +V Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  423  YWGEPIPVIHWEDGTMTTVpeeelplllpeTDEIKPSGTGESPLANIDSFVNVVDEKTGM  482
            YWGEPIP+IHWEDGT T+VPE ELPL+LP T +I+PSGTGESPLAN+   ++V  E  G+
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED-GV  482

Query  483  KGRRETNTMPQWAGSCWYYLRYIDPKNENMLADPEKLKHWLPVDLYIGGVEHAVLHLLYA  542
            KGRRETNTMPQWAGS WYYLRYIDP N + LAD E LK+WLPVD+Y+GG EHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  543  RFWHKVLYDLAIVPTKEPFQKLFNQGMILG------------------------------  572
            RFWHKVLYDL++VPTKEPFQKLFNQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  573  ---EGNEKMSKSKGNVINPDDIVQSHGADTLRLYEMFMGPLDAAIAWSEKGLDGSRRFLD  629
               ++  KMSKS  NV+NPDD+V+  GADTLR+YEMFMGPLDA+IAWSE GL+GSR+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  630  RVWRLMVNEDGTLSSKIVTTNNKSLDKVYNQTVKKVTEDFETLGFNTAISQLMVFINECY  689
            RV RL+   +      I   N+ +LDKVYN+TVK VTE+ + + FNTAI+QLMVF+N   
Sbjct  663  RVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  690  KVDEVYKPYIEGFVKMLAPIAPHIGEELWSKL-GHEESITYQPWPTYDEALLVDDEVEIV  748
            K D ++  Y  GFV+++AP+APH+GEELW  L +  ESI+Y PWP+YDE+ LV+++VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  749  VQVNGKLRAKIKIAKDTSKEEMQEIALSNDNVKASIEGKDIMKVIAVPQKLVNIVAK  805
            VQ++GK++AK+ +AKD S+EE+QE+AL+N++V+A I GKDI+KVIAVP+KLVNIV K
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

362) leuS in NC_017341


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  876 bits (3317),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 545/837 (66%), Positives = 673/837 (81%), Gaps = 42/837 (5%)

Query  3    YNHNQIEKKWQDYWDENKTFKTNDNLGQKKFYALDMFPYPSGAGLHVGHPEGYTATDIIS  62
            Y+H  IE KWQ +W +N TFKT  + ++ KFYALDMFPYPSGAGLHVGHPEGYTATDI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRMQGYNVLHPMGWDAFGLPAEQYALDTGNDPREFTKKNIQTFKRQIKELGFSYDWDR  122
            R+KR QG NVLHPMGWDAFGLPAEQYA+DTGNDP EFT  NI  FKRQI+ LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVNTTDPEYYKWTQWIFIQLYNKGLAYVDEVAVNWCPALGTVLSNEEVI-DGVSERGGHP  181
            EVNTTDP+YYKWTQWIF +LY+KGLAY  EV+VNW   LGT ++NEEV+ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VYRKPMKQWVLKITEYadqlladlddldWPESLKDMQRNWIGRSEGAKVSFDVDNTEGKV  241
            V RKPM+QW+LKIT YA++LL DL+++DWPES+KDMQRNWIG+S GA+V+F V +T+   
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  EVFTTRPDTIYGASFLVLSPEHALVNSITTDEYKEKVKAYQTEASKKSDLERTDLAKDKS  301
             VFTTRPDT++GA++ VL+PEHALV++ITT +  E V  Y+ +AS KSDL RTDLAK+K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYATNPLSGEKVQIWIADYVLSTYGTGAIMAVPAHDDRDYEFAKKFDLPiievie  361
            GV TG+YA NP++G  + +WIADYVL++YGTGAIMAVPAHD+RD EFAK+F+L II V+E
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  ggnveeAAYTGEGKHINSGELDGLENEAAITKAIQLLEQKGAGEKKVNYKLRDWLFSRQR  421
            GGNVEEAA+T +G HINS+ LDGL++ +AI+K ++ LE  G G+ +V Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPVIHWEDGTMTTVpeeelplllpeTDEIKPSGTGESPLANIDSFVNVVDEKTGM  481
            YWGEPIP+IHWEDGT T+VPE ELPL+LP T +I+PSGTGESPLAN+   ++V  E  G+
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED-GV  482

Query  482  KGRRETNTMPQWAGSCWYYLRYIDPKNENMLADPEKLKHWLPVDLYIGGVEHAVLHLLYA  541
            KGRRETNTMPQWAGS WYYLRYIDP N + LAD E LK+WLPVD+Y+GG EHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKVLYDLAIVPTKEPFQKLFNQGMILG------------------------------  571
            RFWHKVLYDL++VPTKEPFQKLFNQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---EGNEKMSKSKGNVINPDDIVQSHGADTLRLYEMFMGPLDAAIAWSEKGLDGSRRFLD  628
               ++  KMSKS  NV+NPDD+V+  GADTLR+YEMFMGPLDA+IAWSE GL+GSR+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RVWRLMVNEDGTLSSKIVTTNNKSLDKVYNQTVKKVTEDFETLGFNTAISQLMVFINECY  688
            RV RL+   +      I   N+ +LDKVYN+TVK VTE+ + + FNTAI+QLMVF+N   
Sbjct  663  RVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  689  KVDEVYKPYIEGFVKMLAPIAPHIGEELWSKL-GHEESITYQPWPTYDEALLVDDEVEIV  747
            K D ++  Y  GFV+++AP+APH+GEELW  L +  ESI+Y PWP+YDE+ LV+++VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  748  VQVNGKLRAKIKIAKDTSKEEMQEIALSNDNVKASIEGKDIMKVIAVPQKLVNIVAK  804
            VQ++GK++AK+ +AKD S+EE+QE+AL+N++V+A I GKDI+KVIAVP+KLVNIV K
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

363) BN843_17610 in NC_021059


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  876 bits (3316),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 545/837 (66%), Positives = 673/837 (81%), Gaps = 42/837 (5%)

Query  4    YNHNQIEKKWQDYWDENKTFKTNDNLGQKKFYALDMFPYPSGAGLHVGHPEGYTATDIIS  63
            Y+H  IE KWQ +W +N TFKT  + ++ KFYALDMFPYPSGAGLHVGHPEGYTATDI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYKRMQGYNVLHPMGWDAFGLPAEQYALDTGNDPREFTKKNIQTFKRQIKELGFSYDWDR  123
            R+KR QG NVLHPMGWDAFGLPAEQYA+DTGNDP EFT  NI  FKRQI+ LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVNTTDPEYYKWTQWIFIQLYNKGLAYVDEVAVNWCPALGTVLSNEEVI-DGVSERGGHP  182
            EVNTTDP+YYKWTQWIF +LY+KGLAY  EV+VNW   LGT ++NEEV+ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VYRKPMKQWVLKITEYadqlladlddldWPESLKDMQRNWIGRSEGAKVSFDVDNTEGKV  242
            V RKPM+QW+LKIT YA++LL DL+++DWPES+KDMQRNWIG+S GA+V+F V +T+   
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  243  EVFTTRPDTIYGASFLVLSPEHALVNSITTDEYKEKVKAYQTEASKKSDLERTDLAKDKS  302
             VFTTRPDT++GA++ VL+PEHALV++ITT +  E V  Y+ +AS KSDL RTDLAK+K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  303  GVFTGAYATNPLSGEKVQIWIADYVLSTYGTGAIMAVPAHDDRDYEFAKKFDLPiievie  362
            GV TG+YA NP++G  + +WIADYVL++YGTGAIMAVPAHD+RD EFAK+F+L II V+E
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  363  ggnveeAAYTGEGKHINSGELDGLENEAAITKAIQLLEQKGAGEKKVNYKLRDWLFSRQR  422
            GGNVEEAA+T +G HINS+ LDGL++ +AI+K ++ LE  G G+ +V Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  423  YWGEPIPVIHWEDGTMTTVpeeelplllpeTDEIKPSGTGESPLANIDSFVNVVDEKTGM  482
            YWGEPIP+IHWEDGT T+VPE ELPL+LP T +I+PSGTGESPLAN+   ++V  E  G+
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED-GV  482

Query  483  KGRRETNTMPQWAGSCWYYLRYIDPKNENMLADPEKLKHWLPVDLYIGGVEHAVLHLLYA  542
            KGRRETNTMPQWAGS WYYLRYIDP N + LAD E LK+WLPVD+Y+GG EHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  543  RFWHKVLYDLAIVPTKEPFQKLFNQGMILG------------------------------  572
            RFWHKVLYDL++VPTKEPFQKLFNQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  573  ---EGNEKMSKSKGNVINPDDIVQSHGADTLRLYEMFMGPLDAAIAWSEKGLDGSRRFLD  629
               ++  KMSKS  NV+NPDD+V+  GADTLR+YEMFMGPLDA+IAWSE GL+GSR+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  630  RVWRLMVNEDGTLSSKIVTTNNKSLDKVYNQTVKKVTEDFETLGFNTAISQLMVFINECY  689
            RV RL+   +      I   N+ +LDKVYN+TVK VTE+ + + FNTAI+QLMVF+N   
Sbjct  663  RVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  690  KVDEVYKPYIEGFVKMLAPIAPHIGEELWSKL-GHEESITYQPWPTYDEALLVDDEVEIV  748
            K D ++  Y  GFV+++AP+APH+GEELW  L +  ESI+Y PWP+YDE+ LV+++VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  749  VQVNGKLRAKIKIAKDTSKEEMQEIALSNDNVKASIEGKDIMKVIAVPQKLVNIVAK  805
            VQ++GK++AK+ +AKD S+EE+QE+AL+N++V+A I GKDI+KVIAVP+KLVNIV K
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

364) leuS in NC_007795


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  876 bits (3316),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 545/837 (66%), Positives = 673/837 (81%), Gaps = 42/837 (5%)

Query  4    YNHNQIEKKWQDYWDENKTFKTNDNLGQKKFYALDMFPYPSGAGLHVGHPEGYTATDIIS  63
            Y+H  IE KWQ +W +N TFKT  + ++ KFYALDMFPYPSGAGLHVGHPEGYTATDI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYKRMQGYNVLHPMGWDAFGLPAEQYALDTGNDPREFTKKNIQTFKRQIKELGFSYDWDR  123
            R+KR QG NVLHPMGWDAFGLPAEQYA+DTGNDP EFT  NI  FKRQI+ LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVNTTDPEYYKWTQWIFIQLYNKGLAYVDEVAVNWCPALGTVLSNEEVI-DGVSERGGHP  182
            EVNTTDP+YYKWTQWIF +LY+KGLAY  EV+VNW   LGT ++NEEV+ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VYRKPMKQWVLKITEYadqlladlddldWPESLKDMQRNWIGRSEGAKVSFDVDNTEGKV  242
            V RKPM+QW+LKIT YA++LL DL+++DWPES+KDMQRNWIG+S GA+V+F V +T+   
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  243  EVFTTRPDTIYGASFLVLSPEHALVNSITTDEYKEKVKAYQTEASKKSDLERTDLAKDKS  302
             VFTTRPDT++GA++ VL+PEHALV++ITT +  E V  Y+ +AS KSDL RTDLAK+K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  303  GVFTGAYATNPLSGEKVQIWIADYVLSTYGTGAIMAVPAHDDRDYEFAKKFDLPiievie  362
            GV TG+YA NP++G  + +WIADYVL++YGTGAIMAVPAHD+RD EFAK+F+L II V+E
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  363  ggnveeAAYTGEGKHINSGELDGLENEAAITKAIQLLEQKGAGEKKVNYKLRDWLFSRQR  422
            GGNVEEAA+T +G HINS+ LDGL++ +AI+K ++ LE  G G+ +V Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  423  YWGEPIPVIHWEDGTMTTVpeeelplllpeTDEIKPSGTGESPLANIDSFVNVVDEKTGM  482
            YWGEPIP+IHWEDGT T+VPE ELPL+LP T +I+PSGTGESPLAN+   ++V  E  G+
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED-GV  482

Query  483  KGRRETNTMPQWAGSCWYYLRYIDPKNENMLADPEKLKHWLPVDLYIGGVEHAVLHLLYA  542
            KGRRETNTMPQWAGS WYYLRYIDP N + LAD E LK+WLPVD+Y+GG EHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  543  RFWHKVLYDLAIVPTKEPFQKLFNQGMILG------------------------------  572
            RFWHKVLYDL++VPTKEPFQKLFNQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  573  ---EGNEKMSKSKGNVINPDDIVQSHGADTLRLYEMFMGPLDAAIAWSEKGLDGSRRFLD  629
               ++  KMSKS  NV+NPDD+V+  GADTLR+YEMFMGPLDA+IAWSE GL+GSR+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  630  RVWRLMVNEDGTLSSKIVTTNNKSLDKVYNQTVKKVTEDFETLGFNTAISQLMVFINECY  689
            RV RL+   +      I   N+ +LDKVYN+TVK VTE+ + + FNTAI+QLMVF+N   
Sbjct  663  RVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  690  KVDEVYKPYIEGFVKMLAPIAPHIGEELWSKL-GHEESITYQPWPTYDEALLVDDEVEIV  748
            K D ++  Y  GFV+++AP+APH+GEELW  L +  ESI+Y PWP+YDE+ LV+++VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  749  VQVNGKLRAKIKIAKDTSKEEMQEIALSNDNVKASIEGKDIMKVIAVPQKLVNIVAK  805
            VQ++GK++AK+ +AKD S+EE+QE+AL+N++V+A I GKDI+KVIAVP+KLVNIV K
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

365) leuS in NC_009641


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  876 bits (3316),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 545/837 (66%), Positives = 673/837 (81%), Gaps = 42/837 (5%)

Query  4    YNHNQIEKKWQDYWDENKTFKTNDNLGQKKFYALDMFPYPSGAGLHVGHPEGYTATDIIS  63
            Y+H  IE KWQ +W +N TFKT  + ++ KFYALDMFPYPSGAGLHVGHPEGYTATDI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYKRMQGYNVLHPMGWDAFGLPAEQYALDTGNDPREFTKKNIQTFKRQIKELGFSYDWDR  123
            R+KR QG NVLHPMGWDAFGLPAEQYA+DTGNDP EFT  NI  FKRQI+ LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVNTTDPEYYKWTQWIFIQLYNKGLAYVDEVAVNWCPALGTVLSNEEVI-DGVSERGGHP  182
            EVNTTDP+YYKWTQWIF +LY+KGLAY  EV+VNW   LGT ++NEEV+ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VYRKPMKQWVLKITEYadqlladlddldWPESLKDMQRNWIGRSEGAKVSFDVDNTEGKV  242
            V RKPM+QW+LKIT YA++LL DL+++DWPES+KDMQRNWIG+S GA+V+F V +T+   
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  243  EVFTTRPDTIYGASFLVLSPEHALVNSITTDEYKEKVKAYQTEASKKSDLERTDLAKDKS  302
             VFTTRPDT++GA++ VL+PEHALV++ITT +  E V  Y+ +AS KSDL RTDLAK+K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  303  GVFTGAYATNPLSGEKVQIWIADYVLSTYGTGAIMAVPAHDDRDYEFAKKFDLPiievie  362
            GV TG+YA NP++G  + +WIADYVL++YGTGAIMAVPAHD+RD EFAK+F+L II V+E
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  363  ggnveeAAYTGEGKHINSGELDGLENEAAITKAIQLLEQKGAGEKKVNYKLRDWLFSRQR  422
            GGNVEEAA+T +G HINS+ LDGL++ +AI+K ++ LE  G G+ +V Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  423  YWGEPIPVIHWEDGTMTTVpeeelplllpeTDEIKPSGTGESPLANIDSFVNVVDEKTGM  482
            YWGEPIP+IHWEDGT T+VPE ELPL+LP T +I+PSGTGESPLAN+   ++V  E  G+
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED-GV  482

Query  483  KGRRETNTMPQWAGSCWYYLRYIDPKNENMLADPEKLKHWLPVDLYIGGVEHAVLHLLYA  542
            KGRRETNTMPQWAGS WYYLRYIDP N + LAD E LK+WLPVD+Y+GG EHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  543  RFWHKVLYDLAIVPTKEPFQKLFNQGMILG------------------------------  572
            RFWHKVLYDL++VPTKEPFQKLFNQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  573  ---EGNEKMSKSKGNVINPDDIVQSHGADTLRLYEMFMGPLDAAIAWSEKGLDGSRRFLD  629
               ++  KMSKS  NV+NPDD+V+  GADTLR+YEMFMGPLDA+IAWSE GL+GSR+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  630  RVWRLMVNEDGTLSSKIVTTNNKSLDKVYNQTVKKVTEDFETLGFNTAISQLMVFINECY  689
            RV RL+   +      I   N+ +LDKVYN+TVK VTE+ + + FNTAI+QLMVF+N   
Sbjct  663  RVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  690  KVDEVYKPYIEGFVKMLAPIAPHIGEELWSKL-GHEESITYQPWPTYDEALLVDDEVEIV  748
            K D ++  Y  GFV+++AP+APH+GEELW  L +  ESI+Y PWP+YDE+ LV+++VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  749  VQVNGKLRAKIKIAKDTSKEEMQEIALSNDNVKASIEGKDIMKVIAVPQKLVNIVAK  805
            VQ++GK++AK+ +AKD S+EE+QE+AL+N++V+A I GKDI+KVIAVP+KLVNIV K
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

366) SAT0131_01867 in NC_017347


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  876 bits (3316),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 545/837 (66%), Positives = 673/837 (81%), Gaps = 42/837 (5%)

Query  4    YNHNQIEKKWQDYWDENKTFKTNDNLGQKKFYALDMFPYPSGAGLHVGHPEGYTATDIIS  63
            Y+H  IE KWQ +W +N TFKT  + ++ KFYALDMFPYPSGAGLHVGHPEGYTATDI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYKRMQGYNVLHPMGWDAFGLPAEQYALDTGNDPREFTKKNIQTFKRQIKELGFSYDWDR  123
            R+KR QG NVLHPMGWDAFGLPAEQYA+DTGNDP EFT  NI  FKRQI+ LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVNTTDPEYYKWTQWIFIQLYNKGLAYVDEVAVNWCPALGTVLSNEEVI-DGVSERGGHP  182
            EVNTTDP+YYKWTQWIF +LY+KGLAY  EV+VNW   LGT ++NEEV+ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VYRKPMKQWVLKITEYadqlladlddldWPESLKDMQRNWIGRSEGAKVSFDVDNTEGKV  242
            V RKPM+QW+LKIT YA++LL DL+++DWPES+KDMQRNWIG+S GA+V+F V +T+   
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  243  EVFTTRPDTIYGASFLVLSPEHALVNSITTDEYKEKVKAYQTEASKKSDLERTDLAKDKS  302
             VFTTRPDT++GA++ VL+PEHALV++ITT +  E V  Y+ +AS KSDL RTDLAK+K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  303  GVFTGAYATNPLSGEKVQIWIADYVLSTYGTGAIMAVPAHDDRDYEFAKKFDLPiievie  362
            GV TG+YA NP++G  + +WIADYVL++YGTGAIMAVPAHD+RD EFAK+F+L II V+E
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  363  ggnveeAAYTGEGKHINSGELDGLENEAAITKAIQLLEQKGAGEKKVNYKLRDWLFSRQR  422
            GGNVEEAA+T +G HINS+ LDGL++ +AI+K ++ LE  G G+ +V Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  423  YWGEPIPVIHWEDGTMTTVpeeelplllpeTDEIKPSGTGESPLANIDSFVNVVDEKTGM  482
            YWGEPIP+IHWEDGT T+VPE ELPL+LP T +I+PSGTGESPLAN+   ++V  E  G+
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED-GV  482

Query  483  KGRRETNTMPQWAGSCWYYLRYIDPKNENMLADPEKLKHWLPVDLYIGGVEHAVLHLLYA  542
            KGRRETNTMPQWAGS WYYLRYIDP N + LAD E LK+WLPVD+Y+GG EHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  543  RFWHKVLYDLAIVPTKEPFQKLFNQGMILG------------------------------  572
            RFWHKVLYDL++VPTKEPFQKLFNQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  573  ---EGNEKMSKSKGNVINPDDIVQSHGADTLRLYEMFMGPLDAAIAWSEKGLDGSRRFLD  629
               ++  KMSKS  NV+NPDD+V+  GADTLR+YEMFMGPLDA+IAWSE GL+GSR+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  630  RVWRLMVNEDGTLSSKIVTTNNKSLDKVYNQTVKKVTEDFETLGFNTAISQLMVFINECY  689
            RV RL+   +      I   N+ +LDKVYN+TVK VTE+ + + FNTAI+QLMVF+N   
Sbjct  663  RVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  690  KVDEVYKPYIEGFVKMLAPIAPHIGEELWSKL-GHEESITYQPWPTYDEALLVDDEVEIV  748
            K D ++  Y  GFV+++AP+APH+GEELW  L +  ESI+Y PWP+YDE+ LV+++VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  749  VQVNGKLRAKIKIAKDTSKEEMQEIALSNDNVKASIEGKDIMKVIAVPQKLVNIVAK  805
            VQ++GK++AK+ +AKD S+EE+QE+AL+N++V+A I GKDI+KVIAVP+KLVNIV K
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

367) leuS in NC_017331


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  876 bits (3316),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 545/837 (66%), Positives = 673/837 (81%), Gaps = 42/837 (5%)

Query  4    YNHNQIEKKWQDYWDENKTFKTNDNLGQKKFYALDMFPYPSGAGLHVGHPEGYTATDIIS  63
            Y+H  IE KWQ +W +N TFKT  + ++ KFYALDMFPYPSGAGLHVGHPEGYTATDI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYKRMQGYNVLHPMGWDAFGLPAEQYALDTGNDPREFTKKNIQTFKRQIKELGFSYDWDR  123
            R+KR QG NVLHPMGWDAFGLPAEQYA+DTGNDP EFT  NI  FKRQI+ LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVNTTDPEYYKWTQWIFIQLYNKGLAYVDEVAVNWCPALGTVLSNEEVI-DGVSERGGHP  182
            EVNTTDP+YYKWTQWIF +LY+KGLAY  EV+VNW   LGT ++NEEV+ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VYRKPMKQWVLKITEYadqlladlddldWPESLKDMQRNWIGRSEGAKVSFDVDNTEGKV  242
            V RKPM+QW+LKIT YA++LL DL+++DWPES+KDMQRNWIG+S GA+V+F V +T+   
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  243  EVFTTRPDTIYGASFLVLSPEHALVNSITTDEYKEKVKAYQTEASKKSDLERTDLAKDKS  302
             VFTTRPDT++GA++ VL+PEHALV++ITT +  E V  Y+ +AS KSDL RTDLAK+K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  303  GVFTGAYATNPLSGEKVQIWIADYVLSTYGTGAIMAVPAHDDRDYEFAKKFDLPiievie  362
            GV TG+YA NP++G  + +WIADYVL++YGTGAIMAVPAHD+RD EFAK+F+L II V+E
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  363  ggnveeAAYTGEGKHINSGELDGLENEAAITKAIQLLEQKGAGEKKVNYKLRDWLFSRQR  422
            GGNVEEAA+T +G HINS+ LDGL++ +AI+K ++ LE  G G+ +V Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  423  YWGEPIPVIHWEDGTMTTVpeeelplllpeTDEIKPSGTGESPLANIDSFVNVVDEKTGM  482
            YWGEPIP+IHWEDGT T+VPE ELPL+LP T +I+PSGTGESPLAN+   ++V  E  G+
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED-GV  482

Query  483  KGRRETNTMPQWAGSCWYYLRYIDPKNENMLADPEKLKHWLPVDLYIGGVEHAVLHLLYA  542
            KGRRETNTMPQWAGS WYYLRYIDP N + LAD E LK+WLPVD+Y+GG EHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  543  RFWHKVLYDLAIVPTKEPFQKLFNQGMILG------------------------------  572
            RFWHKVLYDL++VPTKEPFQKLFNQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  573  ---EGNEKMSKSKGNVINPDDIVQSHGADTLRLYEMFMGPLDAAIAWSEKGLDGSRRFLD  629
               ++  KMSKS  NV+NPDD+V+  GADTLR+YEMFMGPLDA+IAWSE GL+GSR+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  630  RVWRLMVNEDGTLSSKIVTTNNKSLDKVYNQTVKKVTEDFETLGFNTAISQLMVFINECY  689
            RV RL+   +      I   N+ +LDKVYN+TVK VTE+ + + FNTAI+QLMVF+N   
Sbjct  663  RVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  690  KVDEVYKPYIEGFVKMLAPIAPHIGEELWSKL-GHEESITYQPWPTYDEALLVDDEVEIV  748
            K D ++  Y  GFV+++AP+APH+GEELW  L +  ESI+Y PWP+YDE+ LV+++VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  749  VQVNGKLRAKIKIAKDTSKEEMQEIALSNDNVKASIEGKDIMKVIAVPQKLVNIVAK  805
            VQ++GK++AK+ +AKD S+EE+QE+AL+N++V+A I GKDI+KVIAVP+KLVNIV K
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

368) leuS in NC_007793


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  876 bits (3316),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 545/837 (66%), Positives = 673/837 (81%), Gaps = 42/837 (5%)

Query  4    YNHNQIEKKWQDYWDENKTFKTNDNLGQKKFYALDMFPYPSGAGLHVGHPEGYTATDIIS  63
            Y+H  IE KWQ +W +N TFKT  + ++ KFYALDMFPYPSGAGLHVGHPEGYTATDI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYKRMQGYNVLHPMGWDAFGLPAEQYALDTGNDPREFTKKNIQTFKRQIKELGFSYDWDR  123
            R+KR QG NVLHPMGWDAFGLPAEQYA+DTGNDP EFT  NI  FKRQI+ LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVNTTDPEYYKWTQWIFIQLYNKGLAYVDEVAVNWCPALGTVLSNEEVI-DGVSERGGHP  182
            EVNTTDP+YYKWTQWIF +LY+KGLAY  EV+VNW   LGT ++NEEV+ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VYRKPMKQWVLKITEYadqlladlddldWPESLKDMQRNWIGRSEGAKVSFDVDNTEGKV  242
            V RKPM+QW+LKIT YA++LL DL+++DWPES+KDMQRNWIG+S GA+V+F V +T+   
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  243  EVFTTRPDTIYGASFLVLSPEHALVNSITTDEYKEKVKAYQTEASKKSDLERTDLAKDKS  302
             VFTTRPDT++GA++ VL+PEHALV++ITT +  E V  Y+ +AS KSDL RTDLAK+K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  303  GVFTGAYATNPLSGEKVQIWIADYVLSTYGTGAIMAVPAHDDRDYEFAKKFDLPiievie  362
            GV TG+YA NP++G  + +WIADYVL++YGTGAIMAVPAHD+RD EFAK+F+L II V+E
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  363  ggnveeAAYTGEGKHINSGELDGLENEAAITKAIQLLEQKGAGEKKVNYKLRDWLFSRQR  422
            GGNVEEAA+T +G HINS+ LDGL++ +AI+K ++ LE  G G+ +V Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  423  YWGEPIPVIHWEDGTMTTVpeeelplllpeTDEIKPSGTGESPLANIDSFVNVVDEKTGM  482
            YWGEPIP+IHWEDGT T+VPE ELPL+LP T +I+PSGTGESPLAN+   ++V  E  G+
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED-GV  482

Query  483  KGRRETNTMPQWAGSCWYYLRYIDPKNENMLADPEKLKHWLPVDLYIGGVEHAVLHLLYA  542
            KGRRETNTMPQWAGS WYYLRYIDP N + LAD E LK+WLPVD+Y+GG EHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  543  RFWHKVLYDLAIVPTKEPFQKLFNQGMILG------------------------------  572
            RFWHKVLYDL++VPTKEPFQKLFNQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  573  ---EGNEKMSKSKGNVINPDDIVQSHGADTLRLYEMFMGPLDAAIAWSEKGLDGSRRFLD  629
               ++  KMSKS  NV+NPDD+V+  GADTLR+YEMFMGPLDA+IAWSE GL+GSR+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  630  RVWRLMVNEDGTLSSKIVTTNNKSLDKVYNQTVKKVTEDFETLGFNTAISQLMVFINECY  689
            RV RL+   +      I   N+ +LDKVYN+TVK VTE+ + + FNTAI+QLMVF+N   
Sbjct  663  RVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  690  KVDEVYKPYIEGFVKMLAPIAPHIGEELWSKL-GHEESITYQPWPTYDEALLVDDEVEIV  748
            K D ++  Y  GFV+++AP+APH+GEELW  L +  ESI+Y PWP+YDE+ LV+++VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  749  VQVNGKLRAKIKIAKDTSKEEMQEIALSNDNVKASIEGKDIMKVIAVPQKLVNIVAK  805
            VQ++GK++AK+ +AKD S+EE+QE+AL+N++V+A I GKDI+KVIAVP+KLVNIV K
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

369) leuS in NC_010079


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  876 bits (3316),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 545/837 (66%), Positives = 673/837 (81%), Gaps = 42/837 (5%)

Query  4    YNHNQIEKKWQDYWDENKTFKTNDNLGQKKFYALDMFPYPSGAGLHVGHPEGYTATDIIS  63
            Y+H  IE KWQ +W +N TFKT  + ++ KFYALDMFPYPSGAGLHVGHPEGYTATDI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYKRMQGYNVLHPMGWDAFGLPAEQYALDTGNDPREFTKKNIQTFKRQIKELGFSYDWDR  123
            R+KR QG NVLHPMGWDAFGLPAEQYA+DTGNDP EFT  NI  FKRQI+ LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVNTTDPEYYKWTQWIFIQLYNKGLAYVDEVAVNWCPALGTVLSNEEVI-DGVSERGGHP  182
            EVNTTDP+YYKWTQWIF +LY+KGLAY  EV+VNW   LGT ++NEEV+ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VYRKPMKQWVLKITEYadqlladlddldWPESLKDMQRNWIGRSEGAKVSFDVDNTEGKV  242
            V RKPM+QW+LKIT YA++LL DL+++DWPES+KDMQRNWIG+S GA+V+F V +T+   
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  243  EVFTTRPDTIYGASFLVLSPEHALVNSITTDEYKEKVKAYQTEASKKSDLERTDLAKDKS  302
             VFTTRPDT++GA++ VL+PEHALV++ITT +  E V  Y+ +AS KSDL RTDLAK+K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  303  GVFTGAYATNPLSGEKVQIWIADYVLSTYGTGAIMAVPAHDDRDYEFAKKFDLPiievie  362
            GV TG+YA NP++G  + +WIADYVL++YGTGAIMAVPAHD+RD EFAK+F+L II V+E
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  363  ggnveeAAYTGEGKHINSGELDGLENEAAITKAIQLLEQKGAGEKKVNYKLRDWLFSRQR  422
            GGNVEEAA+T +G HINS+ LDGL++ +AI+K ++ LE  G G+ +V Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  423  YWGEPIPVIHWEDGTMTTVpeeelplllpeTDEIKPSGTGESPLANIDSFVNVVDEKTGM  482
            YWGEPIP+IHWEDGT T+VPE ELPL+LP T +I+PSGTGESPLAN+   ++V  E  G+
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED-GV  482

Query  483  KGRRETNTMPQWAGSCWYYLRYIDPKNENMLADPEKLKHWLPVDLYIGGVEHAVLHLLYA  542
            KGRRETNTMPQWAGS WYYLRYIDP N + LAD E LK+WLPVD+Y+GG EHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  543  RFWHKVLYDLAIVPTKEPFQKLFNQGMILG------------------------------  572
            RFWHKVLYDL++VPTKEPFQKLFNQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  573  ---EGNEKMSKSKGNVINPDDIVQSHGADTLRLYEMFMGPLDAAIAWSEKGLDGSRRFLD  629
               ++  KMSKS  NV+NPDD+V+  GADTLR+YEMFMGPLDA+IAWSE GL+GSR+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  630  RVWRLMVNEDGTLSSKIVTTNNKSLDKVYNQTVKKVTEDFETLGFNTAISQLMVFINECY  689
            RV RL+   +      I   N+ +LDKVYN+TVK VTE+ + + FNTAI+QLMVF+N   
Sbjct  663  RVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  690  KVDEVYKPYIEGFVKMLAPIAPHIGEELWSKL-GHEESITYQPWPTYDEALLVDDEVEIV  748
            K D ++  Y  GFV+++AP+APH+GEELW  L +  ESI+Y PWP+YDE+ LV+++VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  749  VQVNGKLRAKIKIAKDTSKEEMQEIALSNDNVKASIEGKDIMKVIAVPQKLVNIVAK  805
            VQ++GK++AK+ +AKD S+EE+QE+AL+N++V+A I GKDI+KVIAVP+KLVNIV K
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

370) leuS in NC_016912


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  876 bits (3317),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 545/837 (66%), Positives = 673/837 (81%), Gaps = 42/837 (5%)

Query  3    YNHNQIEKKWQDYWDENKTFKTNDNLGQKKFYALDMFPYPSGAGLHVGHPEGYTATDIIS  62
            Y+H  IE KWQ +W +N TFKT  + ++ KFYALDMFPYPSGAGLHVGHPEGYTATDI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRMQGYNVLHPMGWDAFGLPAEQYALDTGNDPREFTKKNIQTFKRQIKELGFSYDWDR  122
            R+KR QG NVLHPMGWDAFGLPAEQYA+DTGNDP EFT  NI  FKRQI+ LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVNTTDPEYYKWTQWIFIQLYNKGLAYVDEVAVNWCPALGTVLSNEEVI-DGVSERGGHP  181
            EVNTTDP+YYKWTQWIF +LY+KGLAY  EV+VNW   LGT ++NEEV+ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VYRKPMKQWVLKITEYadqlladlddldWPESLKDMQRNWIGRSEGAKVSFDVDNTEGKV  241
            V RKPM+QW+LKIT YA++LL DL+++DWPES+KDMQRNWIG+S GA+V+F V +T+   
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  EVFTTRPDTIYGASFLVLSPEHALVNSITTDEYKEKVKAYQTEASKKSDLERTDLAKDKS  301
             VFTTRPDT++GA++ VL+PEHALV++ITT +  E V  Y+ +AS KSDL RTDLAK+K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYATNPLSGEKVQIWIADYVLSTYGTGAIMAVPAHDDRDYEFAKKFDLPiievie  361
            GV TG+YA NP++G  + +WIADYVL++YGTGAIMAVPAHD+RD EFAK+F+L II V+E
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  ggnveeAAYTGEGKHINSGELDGLENEAAITKAIQLLEQKGAGEKKVNYKLRDWLFSRQR  421
            GGNVEEAA+T +G HINS+ LDGL++ +AI+K ++ LE  G G+ +V Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPVIHWEDGTMTTVpeeelplllpeTDEIKPSGTGESPLANIDSFVNVVDEKTGM  481
            YWGEPIP+IHWEDGT T+VPE ELPL+LP T +I+PSGTGESPLAN+   ++V  E  G+
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED-GV  482

Query  482  KGRRETNTMPQWAGSCWYYLRYIDPKNENMLADPEKLKHWLPVDLYIGGVEHAVLHLLYA  541
            KGRRETNTMPQWAGS WYYLRYIDP N + LAD E LK+WLPVD+Y+GG EHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKVLYDLAIVPTKEPFQKLFNQGMILG------------------------------  571
            RFWHKVLYDL++VPTKEPFQKLFNQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---EGNEKMSKSKGNVINPDDIVQSHGADTLRLYEMFMGPLDAAIAWSEKGLDGSRRFLD  628
               ++  KMSKS  NV+NPDD+V+  GADTLR+YEMFMGPLDA+IAWSE GL+GSR+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RVWRLMVNEDGTLSSKIVTTNNKSLDKVYNQTVKKVTEDFETLGFNTAISQLMVFINECY  688
            RV RL+   +      I   N+ +LDKVYN+TVK VTE+ + + FNTAI+QLMVF+N   
Sbjct  663  RVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  689  KVDEVYKPYIEGFVKMLAPIAPHIGEELWSKL-GHEESITYQPWPTYDEALLVDDEVEIV  747
            K D ++  Y  GFV+++AP+APH+GEELW  L +  ESI+Y PWP+YDE+ LV+++VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  748  VQVNGKLRAKIKIAKDTSKEEMQEIALSNDNVKASIEGKDIMKVIAVPQKLVNIVAK  804
            VQ++GK++AK+ +AKD S+EE+QE+AL+N++V+A I GKDI+KVIAVP+KLVNIV K
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

371) leuS in NC_018631


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  876 bits (3316),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 522/835 (63%), Positives = 667/835 (80%), Gaps = 41/835 (4%)

Query  3    YEHQKIEQKWQKYWDENQTFATTDDTSKPKYYAMDMFPYPSGQGLHVGHPEGYTATDIMS  62
            Y+H  IE KWQ +W +N+TF T  D+SKPK+YA+DMFPYPSG GLHVGHPEGYTATDI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RFKRANGFNVLHPMGWDAFGLPAEQYAMKTGHNPADFTSQNVDHFREQIKSLGLSYDWNR  122
            RFKRA+G NVLHPMGWDAFGLPAEQYAM TG++PA+FT++N+ +F+ QI++LG+SYDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EINTTDPAYYKWTQWIFEKLYEKGLAYESNMMVNW-DPIDRVVLANEEVIDGKSERSGNK  181
            E+NTTDP YYKWTQWIF KLYEKGLAYE+++ VNW + ++  +  +E + DG SER+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERKALRQWVLKITAYAdrlvddlddldWPEAIKEQQRHWIGRSKGAAVFFNVADSNKKI  241
            V RK++RQW+LKITAYA+RL++DL+++DWPE+IK+ QR+WIG+S GA V F+V D++K +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  EVYTTRPDTLFGASYMVLAPEHQLVDEIATEQQKQAISDYRAIISAKTDLERTDLNKDKT  301
             V+TTRPDTLFGA+Y VLAPEH LVD I+T +Q +A++DY+   S K+DL RTDL K+KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYGVNPINGEKLPIWIADYVLASYGTGAIMAVPAHDDRDFEFAQKFALEIKPVIA  361
            GV TG+Y++NP+NG  +P+WIADYVLASYGTGAIMAVPAHD+RD EFA++F L+I PV+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGDVTKEPYTGDGLHINSDFLDGLDKSTAINTTIAWLETQESGHAQTNFRLRDWIFSRQR  421
            GG+V   ++T DGLHINSDFLDGLDK++AI   + WLE++  G+ +  +RLRDW+FSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPVIHWEDGtttlvpekelplllpHATELRPSGSGESPLANLTDWLEITREDGVK  481
            YWGEPIP+IHWEDGT+T VPE ELPL+LP + ++RPSG+GESPLAN+TDWLE+TREDGVK
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  482  GRRETNTMPQWAGSSWYFLRYIDPRNAEKIADLDKLKYWMNVDLYVGGAEHAVLHLLYAR  541
            GRRETNTMPQWAGSSWY+LRYIDP+N+EK+AD + LK W+ VD+YVGGAEHAVLHLLYAR
Sbjct  484  GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYAR  543

Query  542  FWHKFLYDLGVVPTKEPFQKLVNQGMILGSN-----------------------------  572
            FWHK LYDLGVVPTKEPFQKL NQGMILG++                             
Sbjct  544  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEE  603

Query  573  ----HEKMSKSKGNVVNPDDIVTAFGADTLRVYEMFMGPLTQNKPWSEEGITGSRRWLDR  628
                  KMSKS  NVVNPDD+V  +GADTLRVYEMFMGPL  + +WSEEG+ GSR+ LDR
Sbjct  604  LEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR  663

Query  629  VWRLLIDDEGQVREAVSTYNSGDLDKIYHQTVKKVTEDLENMHFNTAISQMMVFINEAYK  688
            V RL+   E      ++  NSG LDK+Y++TVK VTE++++M FNTAI+Q+MVF+N A K
Sbjct  664  VYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANK  717

Query  689  SEALPINYMTGFVQLLAPIAPHLAEELWVRLGNKA-SISYVTWPQYDQAQLVDDTVEIIF  747
             + L  +Y  GFVQL+AP+APHL+EELW  L   + SISYV WP YD+++LV++ VEI+ 
Sbjct  718  EDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVV  777

Query  748  QVNGKVRGKATVARDLDKDSMIAAAKLDDNVQNFIAEKTIRKVIAIPGKFVNIVV  802
            Q++GKV++K  VA+DL ++ +   A  +++VQ  IA K I KVIA+P K+VNIV+
Sbjct  778  QIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

372) SAKOR_01701 in NC_022226


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  875 bits (3313),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 546/839 (66%), Positives = 675/839 (81%), Gaps = 44/839 (5%)

Query  4    YNHNQIEKKWQDYWDENKTFKTNDNLGQKKFYALDMFPYPSGAGLHVGHPEGYTATDIIS  63
            Y+H  IE KWQ +W +N TFKT  + ++ KFYALDMFPYPSGAGLHVGHPEGYTATDI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYKRMQGYNVLHPMGWDAFGLPAEQYALDTGNDPREFTKKNIQTFKRQIKELGFSYDWDR  123
            R+KR QG NVLHPMGWDAFGLPAEQYA+DTGNDP EFT  NI  FKRQI+ LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVNTTDPEYYKWTQWIFIQLYNKGLAYVDEVAVNWCPALGTVLSNEEVI-DGVSERGGHP  182
            EVNTTDP+YYKWTQWIF +LY+KGLAY  EV+VNW   LGT ++NEEV+ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VYRKPMKQWVLKITEYadqlladlddldWPESLKDMQRNWIGRSEGAKVSFDVDNTEAEG  242
            V RKPM+QW+LKIT YA++LL DL+++DWPES+KDMQRNWIG+S GA+V+F V +T+ + 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKD-  242

Query  243  KVEVFTTRPDTIYGASFLVLSPEHALVNSITTDEYKEKVKAYQTEASKKSDLERTDLAKD  302
               VFTTRPDT++GA++ VL+PEHALV++ITT +  E V  Y+ +AS KSDL RTDLAK+
Sbjct  243  -FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKE  301

Query  303  KSGVFTGAYAINPLSGEKVQIWIADYVLSTYGTGAIMAVPAHDDRDYEFAKKFDLPiiev  362
            K+GV TG+YAINP++G  + +WIADYVL++YGTGAIMAVPAHD+RD EFAK+F+L II V
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  363  ieggnveeAAYTGEGKHINSGELDGLENEAAITKAIQLLEQKGAGEKKVNYKLRDWLFSR  422
            +EGGNVEEAA+T +G HINS+ LDGL++ +AI+K ++ LE  G G+ +V Y+LRDWLFSR
Sbjct  362  LEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSR  421

Query  423  QRYWGEPIPVIHWEDGTMTTVpeeelplllpeTDEIKPSGTGESPLANIDSFVNVVDEKT  482
            QRYWGEPIP+IHWEDGT T+VPE ELPL+LP T +I+PSGTGESPLAN+   ++V  E  
Sbjct  422  QRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED-  480

Query  483  GMKGRRETNTMPQWAGSCWYYLRYIDPKNENMLADPEKLKHWLPVDLYIGGVEHAVLHLL  542
            G+KGRRETNTMPQWAGS WYYLRYIDP N + LAD E LK+WLPVD+Y+GG EHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  543  YARFWHKVLYDLGIVPTKEPFQKLFNQGMILG----------------------------  574
            YARFWHKVLYDLG+VPTKEPFQKLFNQGMILG                            
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  575  -----EGNEKMSKSKGNVINPDDIVQSHGADTLRLYEMFMGPLDAAIAWSEKGLDGSRRF  629
                 ++  KMSKS  NV+NPDD+V+  GADTLR+YEMFMGPLDA+IAWSE GL+GSR+F
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  630  LDRVWRLMVNEDGTLSSKIVTTNNKSLDKVYNQTVKKVTEDFETLGFNTAISQLMVFINE  689
            LDRV RL+   +      I   N+ +LDKVYN+TVK VTE+ + + FNTAI+QLMVF+N 
Sbjct  661  LDRVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNA  714

Query  690  CYKVDEVYKPYIEGFVKMLAPIAPHIGEELWSKL-GHEESITYQPWPTYDEALLVDDEIE  748
              K D ++  Y  GFV+++AP+APH+GEELW  L +  ESI+Y PWP+YDE+ LV++++E
Sbjct  715  ANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVE  774

Query  749  IVVQVNGKLRAKIKIAKDTSKEEMQEIALSNDNVKASIEGKDIMKVIAVPQKLVNIVAK  807
            IVVQ++GK++AK+ +AKD S+EE+QE+AL+N++V+A I GKDI+KVIAVP+KLVNIV K
Sbjct  775  IVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

373) leuS in NC_002953


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  875 bits (3315),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 547/839 (66%), Positives = 675/839 (81%), Gaps = 44/839 (5%)

Query  3    YNHNQIEKKWQDYWDENKTFKTNDNLGQKKFYALDMFPYPSGAGLHVGHPEGYTATDIIS  62
            Y+H  IE KWQ +W +N TFKT  + ++ KFYALDMFPYPSGAGLHVGHPEGYTATDI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRMQGYNVLHPMGWDAFGLPAEQYALDTGNDPREFTKKNIQTFKRQIKELGFSYDWDR  122
            R+KR QG NVLHPMGWDAFGLPAEQYA+DTGNDP EFT  NI  FKRQI+ LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVNTTDPEYYKWTQWIFIQLYNKGLAYVDEVAVNWCPALGTVLSNEEVI-DGVSERGGHP  181
            EVNTTDP+YYKWTQWIF +LY+KGLAY  EV+VNW   LGT ++NEEV+ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VYRKPMKQWVLKITEYadqlladlddldWPESLKDMQRNWIGRSEGAKVSFDVDNTEAEG  241
            V RKPM+QW+LKIT YA++LL DL+++DWPES+KDMQRNWIG+S GA+V+F V +T+ + 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKD-  242

Query  242  KVEVFTTRPDTIYGASFLVLSPEHALVNSITTDEYKEKVKAYQTEASKKSDLERTDLAKD  301
               VFTTRPDT++GA++ VL+PEHALV++ITT +  E V  Y+ +AS KSDL RTDLAK+
Sbjct  243  -FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKE  301

Query  302  KSGVFTGAYAINPLSGEKVQIWIADYVLSTYGTGAIMAVPAHDDRDYEFAKKFDLPiiev  361
            K+GV TG+YAINP++G  + +WIADYVL++YGTGAIMAVPAHD+RD EFAK+F+L II V
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  362  ieggnveeAAYTGEGKHINSGELDGLENEAAITKAIQLLEQKGAGEKKVNYKLRDWLFSR  421
            +EGGNVEEAA+T +G HINS+ LDGL++ +AI+K ++ LE  G G+ +V Y+LRDWLFSR
Sbjct  362  LEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSR  421

Query  422  QRYWGEPIPVIHWEDGTMTTVpeeelplllpeTDEIKPSGTGESPLANIDSFVNVVDEKT  481
            QRYWGEPIP+IHWEDGT T+VPE ELPL+LP T +I+PSGTGESPLAN+   ++V  E  
Sbjct  422  QRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED-  480

Query  482  GMKGRRETNTMPQWAGSCWYYLRYIDPKNENMLADPEKLKHWLPVDLYIGGVEHAVLHLL  541
            G+KGRRETNTMPQWAGS WYYLRYIDP N + LAD E LK+WLPVD+Y+GG EHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  542  YARFWHKVLYDLGIVPTKEPFQKLFNQGMILG----------------------------  573
            YARFWHKVLYDLG+VPTKEPFQKLFNQGMILG                            
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  574  -----EGNEKMSKSKGNVINPDDIVQSHGADTLRLYEMFMGPLDAAIAWSEKGLDGSRRF  628
                 ++  KMSKS  NV+NPDD+V+  GADTLR+YEMFMGPLDA+IAWSE GL+GSR+F
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  629  LDRVWRLMVNEDGTLSSKIVTTNNKSLDKVYNQTVKKVTEDFETLGFNTAISQLMVFINE  688
            LDRV RL+   +      I   N+ +LDKVYN+TVK VTE+ + + FNTAI+QLMVF+N 
Sbjct  661  LDRVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNA  714

Query  689  CYKVDEVYKPYIEGFVKMLAPIAPHIGEELWSKL-GHEESITYQPWPTYDEALLVDDEVE  747
              K D ++  Y  GFV+++AP+APH+GEELW  L +  ESI+Y PWP+YDE+ LV+++VE
Sbjct  715  ANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVE  774

Query  748  IVVQVNGKLRAKIKIAKDTSKEEMQEIALSNDNVKASIEGKDIMKVIAVPQKLVNIVAK  806
            IVVQ++GK++AK+ +AKD S+EE+QE+AL+N++V+A I GKDI+KVIAVP+KLVNIV K
Sbjct  775  IVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

374) leuS in NC_003923


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  875 bits (3312),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 547/839 (66%), Positives = 675/839 (81%), Gaps = 44/839 (5%)

Query  4    YNHNQIEKKWQDYWDENKTFKTNDNLGQKKFYALDMFPYPSGAGLHVGHPEGYTATDIIS  63
            Y+H  IE KWQ +W +N TFKT  + ++ KFYALDMFPYPSGAGLHVGHPEGYTATDI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYKRMQGYNVLHPMGWDAFGLPAEQYALDTGNDPREFTKKNIQTFKRQIKELGFSYDWDR  123
            R+KR QG NVLHPMGWDAFGLPAEQYA+DTGNDP EFT  NI  FKRQI+ LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVNTTDPEYYKWTQWIFIQLYNKGLAYVDEVAVNWCPALGTVLSNEEVI-DGVSERGGHP  182
            EVNTTDP+YYKWTQWIF +LY+KGLAY  EV+VNW   LGT ++NEEV+ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VYRKPMKQWVLKITEYadqlladlddldWPESLKDMQRNWIGRSEGAKVSFDVDNTEAEG  242
            V RKPM+QW+LKIT YA++LL DL+++DWPES+KDMQRNWIG+S GA+V+F V +T+ + 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKD-  242

Query  243  KVEVFTTRPDTIYGASFLVLSPEHALVNSITTDEYKEKVKAYQTEASKKSDLERTDLAKD  302
               VFTTRPDT++GA++ VL+PEHALV++ITT +  E V  Y+ +AS KSDL RTDLAK+
Sbjct  243  -FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKE  301

Query  303  KSGVFTGAYAINPLSGEKVQIWIADYVLSTYGTGAIMAVPAHDDRDYEFAKKFDLPiiev  362
            K+GV TG+YAINP++G  + +WIADYVL++YGTGAIMAVPAHD+RD EFAK+F+L II V
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  363  ieggnveeAAYTGEGKHINSGELDGLENEAAITKAIQLLEQKGAGEKKVNYKLRDWLFSR  422
            +EGGNVEEAA+T +G HINS+ LDGL++ +AI+K ++ LE  G G+ +V Y+LRDWLFSR
Sbjct  362  LEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSR  421

Query  423  QRYWGEPIPVIHWEDGTMTTVpeeelplllpeTDEIKPSGTGESPLANIDSFVNVVDEKT  482
            QRYWGEPIP+IHWEDGT T+VPE ELPL+LP T +I+PSGTGESPLAN+   ++V  E  
Sbjct  422  QRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED-  480

Query  483  GMKGRRETNTMPQWAGSCWYYLRYIDPKNENMLADPEKLKHWLPVDLYIGGVEHAVLHLL  542
            G+KGRRETNTMPQWAGS WYYLRYIDP N + LAD E LK+WLPVD+Y+GG EHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  543  YARFWHKVLYDLGIVPTKEPFQKLFNQGMILG----------------------------  574
            YARFWHKVLYDLG+VPTKEPFQKLFNQGMILG                            
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  575  -----EGNEKMSKSKGNVINPDDIVQSHGADTLRLYEMFMGPLDAAIAWSEKGLDGSRRF  629
                 ++  KMSKS  NV+NPDD+V+  GADTLR+YEMFMGPLDA+IAWSE GL+GSR+F
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  630  LDRVWRLMVNEDGTLSSKIVTTNNKSLDKVYNQTVKKVTEDFETLGFNTAISQLMVFINE  689
            LDRV RL+   +      I   N+ +LDKVYN+TVK VTE+ + + FNTAI+QLMVF+N 
Sbjct  661  LDRVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNA  714

Query  690  CYKVDEVYKPYIEGFVKMLAPIAPHIGEELWSKL-GHEESITYQPWPTYDEALLVDDEVE  748
              K D ++  Y  GFV+++AP+APH+GEELW  L +  ESI+Y PWP+YDE+ LV+++VE
Sbjct  715  ANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVE  774

Query  749  IVVQVNGKLRAKIKIAKDTSKEEMQEIALSNDNVKASIEGKDIMKVIAVPQKLVNIVAK  807
            IVVQ++GK++AK+ +AKD S+EE+QE+AL+N++V+A I GKDI+KVIAVP+KLVNIV K
Sbjct  775  IVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

375) leuS in NC_014319


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  875 bits (3315),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 524/835 (63%), Positives = 669/835 (81%), Gaps = 41/835 (4%)

Query  3    YEHQKIEQKWQKYWDENQTFATTDDTSKPKYYAMDMFPYPSGQGLHVGHPEGYTATDIMS  62
            Y+H  IE KWQ +W +N+TF T  D+SKPK+YA+DMFPYPSG GLHVGHPEGYTATDI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RFKRANGFNVLHPMGWDAFGLPAEQYAMKTGHNPADFTSQNVDHFREQIKSLGLSYDWNR  122
            RFKRA+G NVLHPMGWDAFGLPAEQYAM TG++PA+FT++N+ +F+ QI++LG+SYDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EINTTDPTYYKWTQWIFEKLYEKGLAYESNMMVNW-DPIDRVVLANEEVIDGKSERSGNK  181
            E+NTTDP YYKWTQWIF KLYEKGLAYE+++ VNW + ++  +  +E + DG SER+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERKALRQWVLKITAYAdrlvddlddldWPEAIKEQQRHWIGRSKGAAVFFNVLDSNRQI  241
            V RK++RQW+LKITAYA+RL++DL+++DWPE+IK+ QR+WIG+S GA V F+V D+++++
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  EVYTTRPDTLFGASYMVLAPEHQLVDEIATEKQKQAISDYRAIISAKTDLERTDLNKDKT  301
             V+TTRPDTLFGA+Y VLAPEH LVD I+T  Q +A++DY+   S K+DL RTDL K+KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYGINPINGEKLPIWIADYVLASYGTGAIMAVPAHDDRDFEFAQKFDLKIKPVIA  361
            GV TG+Y+INP+NG  +P+WIADYVLASYGTGAIMAVPAHD+RD EFA++F+L I PV+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGDVTKEPYTGDGLHINSDFLDGLDKSTAITSAITWLETHESGHAQTNFRLRDWIFSRQR  421
            GG+V   ++T DGLHINSDFLDGLDK++AI+  + WLE++  G+ +  +RLRDW+FSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPVIHWEDGtttlvpekelplllpHATELRPSGSGESPLANLTDWLEVTREDGVK  481
            YWGEPIP+IHWEDGT+T VPE ELPL+LP + ++RPSG+GESPLAN+TDWLEVTREDGVK
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  482  GRRETNTMPQWAGSSWYFLRYIDPHNAEKIADLDKLKYWMNVDLYVGGAEHAVLHLLYAR  541
            GRRETNTMPQWAGSSWY+LRYIDPHN+EK+AD + LK W+ VD+YVGGAEHAVLHLLYAR
Sbjct  484  GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYAR  543

Query  542  FWHKFLYDLGVVPTKEPFQKLVNQGMILGSN-----------------------------  572
            FWHK LYDLGVVPTKEPFQKL NQGMILG++                             
Sbjct  544  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEE  603

Query  573  ----HEKMSKSKGNVVNPDDIVMAFGADTLRVYEMFMGPLTQNKPWSEEGITGSRRWLDR  628
                  KMSKS  NVVNPDD+V  +GADTLRVYEMFMGPL  + +WSEEG+ GSR+ LDR
Sbjct  604  LEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR  663

Query  629  VWRLLIDDEGQVREAVSTYNSGDLDKIYHQTVKKVTEDLENMHFNTAISQMMVFINEAYK  688
            V RL+   E      ++  NSG LDK+Y++TVK VTE++++M FNTAI+Q+MVF+N A K
Sbjct  664  VYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANK  717

Query  689  SEALPINYMTGFVQLLAPIAPHLAEELWVRL-GNEASISYVTWPQYDQAQLVDDTVEIIF  747
             + L  +Y  GFVQL+AP+APHL+EELW  L ++  SISYV WP YD+++LV++ VEI+ 
Sbjct  718  EDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVV  777

Query  748  QVNGKVRGKATVARDLDKDSMIAAAKLDDNVQNFIAEKTIRKVIAIPGKFVNIVV  802
            Q++GKV++K  VA+DL ++ +   A  +++VQ  IA K I KVIA+P K+VNIV+
Sbjct  778  QIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

376) SAMSHR1132_16080 in NC_016941


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  872 bits (3301),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 553/837 (67%), Positives = 675/837 (81%), Gaps = 42/837 (5%)

Query  3    YNHNQIEKKWQDYWDENKTFKTNDNLGQKKFYALDMFPYPSGAGLHVGHPEGYTATDIIS  62
            Y+H  IE KWQ +W +N TFKT  + ++ KFYALDMFPYPSGAGLHVGHPEGYTATDI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRMQGYNVLHPMGWDAFGLPAEQYALDTGNDPREFTKKNIQTFKRQIKELGFSYDWDR  122
            R+KR QG NVLHPMGWDAFGLPAEQYA+DTGNDP EFT  NI  FKRQI+ LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVNTTDPEYYKWTQWIFIQLYNKGLAYVDEVAVNWCPALGTVLSNEEVI-DGVSERGGHP  181
            EVNTTDP+YYKWTQWIF +LY+KGLAY  EV+VNW   LGT ++NEEV+ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VYRKPMKQWVLKITEYAdqllvdlddldWPESLKDMQRNWIGRSEGAKVSFGVKDTDEKV  241
            V RKPM+QW+LKIT YA++LL DL+++DWPES+KDMQRNWIG+S GA+V+F VKDTD   
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  EVFTTRPDTIYGASFLVLSPEHALVDLITTDEYKEEVKAYQTEASKKSDLERTDLAKDKT  301
             VFTTRPDT++GA++ VL+PEHALVD ITT +  E V  Y+ +AS KSDL RTDLAK+KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAINPLSGEKLPIWIADYVLSTYGTGAIMAVPAHDERDYEFAKKYELPiievie  361
            GV TG+YAINP++G  +P+WIADYVL++YGTGAIMAVPAHDERD EFAK+++L II V+E
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  ggnveeAAYTGEGKHINSgelngleneeAISRAIQLLEQKGAGEKKVNYKLRDWLFSRQR  421
            GGNVEEAA+T +G HINS+ L+GL++  AI++ ++ LE  G G+ +V Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPVIHWEDGTMTTVpeeelplllpeTDEIKPSGTGESPLANIDSFVNVVDEKTGM  481
            YWGEPIP+IHWEDGT T+VPE ELPL+LP T +I+PSGTGESPLAN+   ++V  E  G+
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED-GV  482

Query  482  KGRRETNTMPQWAGSCWYYLRYIDPKNENMLADPEKLKHWLPVDLYIGGVEHAVLHLLYA  541
            KGRRETNTMPQWAGS WYYLRYIDP N + LAD E LK+WLPVD+Y+GG EHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKVLYDLGVVPTKEPFQKLFNQGMILG------------------------------  571
            RFWHKVLYDLGVVPTKEPFQKLFNQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---EGNEKMSKSKGNVINPDDIVQSHGADTLRLYEMFMGPLDAAIAWSENGLDGSRRFLD  628
               ++  KMSKS  NV+NPDD+V+  GADTLR+YEMFMGPLDA+IAWSE+GL+GSR+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RVWRLMVNEDGSLSSKIVTTNNKSLDKVYNQTVKKVTEDFETLGFNTAISQLMVFINECY  688
            RV RL+   +      I   N+ +LDKVYN+TVK VTE+ + + FNTAI+QLMVF+N   
Sbjct  663  RVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  689  KVDEVYKPYIEGFVKMLAPIAPHIGEELWSKL-GHEESITYQPWPTYDESLLVDDEVEIV  747
            K D ++  Y  GFV+++AP+APH+GEELW  L +  ESI+Y PWP+YDES LV+++VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  748  VQVNGKLRAKIKIAKDTSKEEMQEIALSNDNVKASIEGKDIMKVIAVPQKLVNIVAK  804
            VQ++GK++AK+ +AKD S+EE+QE+AL+N++V+A I GKDI+KVIAVP+KLVNIV K
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

377) leuS in NC_015734


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  872 bits (3302),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 520/835 (63%), Positives = 668/835 (80%), Gaps = 41/835 (4%)

Query  3    YEHQKIETKWQKYWDEYQTFATSDETNKPKYYAVDMFPYPSGQGLHVGHPEGYTATDIMS  62
            Y+H  IE KWQ +W + +TF T+ +++KPK+YA+DMFPYPSG GLHVGHPEGYTATDI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RFKRTQGFNVLHPMGWDAFGLPAEQYALKTGHNPADFTSQNVAHFREQIKSLGLSYDWNR  122
            RFKR+QG NVLHPMGWDAFGLPAEQYA+ TG++PA+FT++N+A+F+ QI++LG+SYDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EINTTDPKFYKWTQWIFEKLYEKGLAYESNMMVNW-DPIDRVVLANEEVIDGKSERSGNK  181
            E+NTTDP++YKWTQWIF KLYEKGLAYE+++ VNW + ++  +  +E + DG SER+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERKALRQWVLKITAYAdrlvddlddldWPEAIKEQQRHWIGRSKGAAVFFKVANTDKQI  241
            V RK++RQW+LKITAYA+RL++DL+++DWPE+IK+ QR+WIG+S GA V FKV +TDK++
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  EVYTTRPDTLFGASYMVLAPEHTLVDDIVTDAQKQAVANYRADIAAKSDLERTDLNKDKT  301
             V+TTRPDTLFGA+Y VLAPEH+LVD I T  Q +AVA+Y+ + + KSDL RTDL K+KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYGINPINGEKLPIWIADYVLASYGTGAIMAVPAHDTRDFDFAKKFDLNIKPVIA  361
            GV TG+Y+INP+NG  +P+WIADYVLASYGTGAIMAVPAHD RD +FAK+F+L+I PV+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGDSTKEAYMGDGTHINSGFLDGLDKASAIDQTISWLESHQAGHAQTNFRLRDWIFSRQR  421
            GG+    A+  DG HINS+FLDGLDKASAI + + WLE++  G+ +  +RLRDW+FSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPVIHWEDGTTSlvpekelplllpRATELRPSGSGESPLANLTDWLEVTREDGVK  481
            YWGEPIP+IHWEDGT++ VPE ELPL+LP + ++RPSG+GESPLAN+TDWLEVTREDGVK
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  482  GRRETNTMPQWAGSSWYFLRYIDPHNDEVLADSDKLKYWMNVDLYVGGAEHAVLHLLYAR  541
            GRRETNTMPQWAGSSWY+LRYIDPHN E LAD + LK W+ VD+YVGGAEHAVLHLLYAR
Sbjct  484  GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYAR  543

Query  542  FWHKFLYDLGVVPTKEPFQKLVNQGMILGAN-----------------------------  572
            FWHK LYDLGVVPTKEPFQKL NQGMILG++                             
Sbjct  544  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEE  603

Query  573  ----HEKMSKSKGNVVNPDDIVAAFGADTLRVYEMFMGPLTQNKPWSEEGITGSRRWLDR  628
                  KMSKS  NVVNPDD+V  +GADTLRVYEMFMGPL  + +WSEEG+ GSR+ LDR
Sbjct  604  LEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR  663

Query  629  VWrlliddndrlrdHVTTYNPGDLDKIYNQTVKKVTEDLENMRFNTAISQMMVFVNEAYK  688
            V             ++T  N+G LDK+YN+TVK VTE++++M+FNTAI+Q+MVFVN A K
Sbjct  664  VY------RLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANK  717

Query  689  SDALPLDYMNGFIQLLAPFAPHLAEELWVRL-GNEASISYVTWPTYDQAQLVDDTVEIIF  747
             D L  DY +GF+QL+APFAPHL+EELW  L ++  SISYV WP+YD+++LV++ VEI+ 
Sbjct  718  EDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVV  777

Query  748  QVNGKVRGKATVTRDIDKDSMIASAKLDDNVQNFIAGKTVRKIIAIPGKFVNIVV  802
            Q++GKV++K  V++D+ ++ +   A  +++VQ  IAGK + K+IA+P K+VNIV+
Sbjct  778  QIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

378) leuS in NC_014136


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  872 bits (3302),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 520/835 (63%), Positives = 668/835 (80%), Gaps = 41/835 (4%)

Query  3    YEHQKIETKWQKYWDEYQTFATSDETNKPKYYAVDMFPYPSGQGLHVGHPEGYTATDIMS  62
            Y+H  IE KWQ +W + +TF T+ +++KPK+YA+DMFPYPSG GLHVGHPEGYTATDI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RFKRTQGFNVLHPMGWDAFGLPAEQYALKTGHNPADFTSQNVAHFREQIKSLGLSYDWNR  122
            RFKR+QG NVLHPMGWDAFGLPAEQYA+ TG++PA+FT++N+A+F+ QI++LG+SYDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EINTTDPKFYKWTQWIFEKLYEKGLAYESNMMVNW-DPIDRVVLANEEVIDGKSERSGNK  181
            E+NTTDP++YKWTQWIF KLYEKGLAYE+++ VNW + ++  +  +E + DG SER+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERKALRQWVLKITAYAdrlvddlddldWPEAIKEQQRHWIGRSKGAAVFFKVANTDKQI  241
            V RK++RQW+LKITAYA+RL++DL+++DWPE+IK+ QR+WIG+S GA V FKV +TDK++
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  EVYTTRPDTLFGASYMVLAPEHTLVDDIVTDAQKQAVANYRADIAAKSDLERTDLNKDKT  301
             V+TTRPDTLFGA+Y VLAPEH+LVD I T  Q +AVA+Y+ + + KSDL RTDL K+KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYGINPINGEKLPIWIADYVLASYGTGAIMAVPAHDTRDFDFAKKFDLNIKPVIA  361
            GV TG+Y+INP+NG  +P+WIADYVLASYGTGAIMAVPAHD RD +FAK+F+L+I PV+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGDSTKEAYMGDGTHINSGFLDGLDKASAIDQTISWLESHQAGHAQTNFRLRDWIFSRQR  421
            GG+    A+  DG HINS+FLDGLDKASAI + + WLE++  G+ +  +RLRDW+FSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPVIHWEDGTTSlvpekelplllpRATELRPSGSGESPLANLTDWLEVTREDGVK  481
            YWGEPIP+IHWEDGT++ VPE ELPL+LP + ++RPSG+GESPLAN+TDWLEVTREDGVK
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  482  GRRETNTMPQWAGSSWYFLRYIDPHNDEVLADSDKLKYWMNVDLYVGGAEHAVLHLLYAR  541
            GRRETNTMPQWAGSSWY+LRYIDPHN E LAD + LK W+ VD+YVGGAEHAVLHLLYAR
Sbjct  484  GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYAR  543

Query  542  FWHKFLYDLGVVPTKEPFQKLVNQGMILGAN-----------------------------  572
            FWHK LYDLGVVPTKEPFQKL NQGMILG++                             
Sbjct  544  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEE  603

Query  573  ----HEKMSKSKGNVVNPDDIVAAFGADTLRVYEMFMGPLTQNKPWSEEGITGSRRWLDR  628
                  KMSKS  NVVNPDD+V  +GADTLRVYEMFMGPL  + +WSEEG+ GSR+ LDR
Sbjct  604  LEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR  663

Query  629  VWrlliddndrlrdHVTTYNPGDLDKIYNQTVKKVTEDLENMRFNTAISQMMVFVNEAYK  688
            V             ++T  N+G LDK+YN+TVK VTE++++M+FNTAI+Q+MVFVN A K
Sbjct  664  VY------RLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANK  717

Query  689  SDALPLDYMNGFIQLLAPFAPHLAEELWVRL-GNEASISYVTWPTYDQAQLVDDTVEIIF  747
             D L  DY +GF+QL+APFAPHL+EELW  L ++  SISYV WP+YD+++LV++ VEI+ 
Sbjct  718  EDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVV  777

Query  748  QVNGKVRGKATVTRDIDKDSMIASAKLDDNVQNFIAGKTVRKIIAIPGKFVNIVV  802
            Q++GKV++K  V++D+ ++ +   A  +++VQ  IAGK + K+IA+P K+VNIV+
Sbjct  778  QIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

379) Bcell_3314 in NC_014829


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  871 bits (3297),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 547/838 (66%), Positives = 664/838 (80%), Gaps = 43/838 (5%)

Query  3    FDHQFVEQKWQKVWEENKTFKVEENTTKENFYALDMFPYPSGSGLHVGHPEGYTATDILS  62
            +DH  +E KWQ  W +N TFK   +++K +FYALDMFPYPSG+GLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMRRMQGYNVLHPMGWDAFGLPAEQYALDTGNHPNEFTVKNIDVFRKQIKALGFSYDWDR  122
            R +R QG NVLHPMGWDAFGLPAEQYA+DTGN+P EFT  NI  F++QI+ALGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVNTTDESYYKWTQWIFLKLYEKGLAYVDEVAVNWCPALGTVLANEEVI-DGKSERGGHP  181
            EVNTTD +YYKWTQWIF KLYEKGLAY  EV+VNW   LGT +ANEEV+ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRPMKQWMLRITAYAdrlledleeldWPESLKDMQRNWIGRSEGADVTFDVEGVDNTI  241
            V R+PM+QWML+ITAYA+RLLEDLEE+DWPES+KDMQRNWIG+S GA+VTF V + D+ +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  TVFTTRPDTLYGATYIVLAPEHKLVERIVTPEQFEAVDEYQKKVATKSDLERTELAKDKT  301
            TVFTTRPDTL+GATY VLAPEH LV+ I T++Q EAV +Y+++ + KSDL RT+LAK+KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAIHPVSGEKLPIWIADYVLVNYGTGAIMAVPGHDERDYEFAQAFDLPIVEVVS  361
            GV TG+YAI+PV+G  +P+WIADYVL +YGTGAIMAVP+HDERD EFA+ F+L I+ V+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGDLSKEAYTGDGPHVNSDFLNGLDKEEAISKMIEWLENNNRGERKVTYRLRDWLFSRQR  421
            GG++   A+T DG H+NSDFL+GLDK  AI+KM+EWLE +  G+ +VTYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPIIHFEDGTMKAVpeeelpltlpeleeFKPSGEGESPLANATDWLYVTDPETGK  481
            YWGEPIPIIH EDGT  AVPE ELPL LP   +++PSG GESPLAN TDWL VT  E G 
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT-REDGV  482

Query  482  KGRRETNTMPQWAGSCWYYLRYIDPHNDEALADPELLKKWLPVDIYIGGAEHAVLHLLYA  541
            KGRRETNTMPQWAGS WYYLRYIDPHN E LAD ELLK+WLPVDIY+GGAEHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKFLYDIGVVPTKEPFQKLYNQGMILG------------------------------  571
            RFWHK LYD+GVVPTKEPFQKL+NQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---EGNEKMSKSKGNVVNPDDIIKSHGADTLRLYEMFMGPLDASIAWSTNGLDGARRFLD  628
               ++  KMSKS  NVVNPDD++   GADTLR+YEMFMGPLDASIAWS +GL+G+R+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RVWRLIVSDNGELNHAIVDKEGSAHMTRAYHQTVKKVTEDFEGLRFNTGISQMMVFVNEA  688
            RV RLI + +       +  E S+ + + Y++TVK VTE+ + ++FNT+I+Q+MVFVN A
Sbjct  663  RVYRLITTKE-------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAA  715

Query  689  YKQEELCKSHIEGFVKLLSPVAPHISEELWSKL-GHEETIAYATWPIYDESLLvenevei  747
             K++ L      GFV+L++P APH++EELW  L +  E+I+Y  WP YDES LVEN+VEI
Sbjct  716  NKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEI  775

Query  748  vvqvnGKVRSKLVIAKDASREDMEQKAVEIDKVKEEIEGKTVRKVIAVPGKLVNIVAN  805
            VVQ++GKV++KLV+AKD SRE++++ A+  +KV+ EI GK + KVIAVP KLVNIV +
Sbjct  776  VVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

380) leuS in NC_015601


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  870 bits (3294),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 497/814 (62%), Positives = 634/814 (78%), Gaps = 37/814 (4%)

Query  2    YNHLKIEKKWQNYWDEHETFKTDVHNFDLPKYYVLDMFPYPSGNGLHVGHPRGYTATDVI  61
            Y+H  IE KWQ +W +++TFKT+ +    PK+Y LDMFPYPSG GLHVGHP GYTATD++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDA-SKPKFYALDMFPYPSGAGLHVGHPEGYTATDIL  62

Query  62   ARYKRMNGFNVLHPMGWDAFGLPAEQFALKTGNHPNEFTKQNIDHFTDQIKSLGLSYDWS  121
            +R+KR +G NVLHPMGWDAFGLPAEQ+A+ TGN+P EFT +NI +F  QI++LG+SYDW 
Sbjct  63   SRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWD  122

Query  122  REISTTDPGYYKWTQWIFTKLYDMGLAYVDEKPVNFCPELGTVLANEEVI-DGKSEVGGF  180
            RE++TTDP YYKWTQWIFTKLY+ GLAY  E PVN   ELGT +ANEEV+ DG SE GG+
Sbjct  123  REVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGY  182

Query  181  DVIRMPMRQWVLKITEYADRLLEDLDLVEWPDSTKEMQINWIGRSEGSNVIFKIADHDKE  240
             V+R PMRQW+LKIT YA+RLLEDL+ V+WP+S K+MQ NWIG+S G+NV FK+ D DK+
Sbjct  183  PVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  241  FTVFTTRADTLFGNTYCVLAPEHPFVKEITTAENIDEVNAYVEKVLHKSDLERTELNKEK  300
            FTVFTTR+DTLFG TY VLAPEH++V  ITT+++ + V  Y  +   KSDL RT+L KEK
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEK  302

Query  301  SGVFTGAYAINPVNGKKVPIYIADYVLAAYGTGAIMAVPAHDTRDFEFAKKYNLEIIPVI  360
            +GV TG+YAINPVNGK +P+ IADYVLA+YGTGAIMAVPAHD RD EFAK++NL+IIPV+
Sbjct  303  TGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL  362

Query  361  EGGDIAVEAYTGDGIHINSGFLDGMGKDEAIETMQSWLVENGYGEAKTTYKLRDWLFSRQ  420
            EGG++   A+T DG+HINS+FLDG++K  AI  M  WL  +G G+ + TY+LRDWLFSRQ
Sbjct  363  EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQ  422

Query  421  RYWGEPIPIVHLEDGTMRTVEIDELPLELPEVEHYKPASDGQSPLANAGDWLDVTFADGT  480
            RYWGEPIPI+H EDGT  +V   ELPL LP   + +P++ G+SPLAN  DWL+VT  DG 
Sbjct  423  RYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGV  482

Query  481  KGRRETNTMPQWAGSCWYYLRYIDPENNEAIGDPELLKHWMPVDLYMGGSEHAVLHLLYA  540
            KGRRETNTMPQWAGS WYYLRYIDP+N E ++D ELLK+W+PVD+Y+GG+EHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  541  RFWHKVLFDLGVVDTKEPFGKLYHQGMILGAN----------------------------  572
            RFWHKVL+DLGVV TKEPF KL++QGMILG++                            
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  573  -----NEKMSKSRGNVVNPDDIVESHGADALRVYEMFMGPLDGAIAWSTRGLDGIRKWLD  627
                   KMSKS  NVVNPDD+VE  GAD+LRVYEMFMGPLD++IAWS  GL+G RK LD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  628  RVYRLMVESDKISETNDGSLDFVYNQTVQKVTHDIETFGMNTAISQLMIFVNEAYKAETL  687
            RVYRL+   + I+E N G+LD VYN+TV+ VT++++    NTAI+QLM+FVN A K + L
Sbjct  663  RVYRLITTKE-ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKL  721

Query  688  YKEYALGFIKMLACFAPHLGEELYEIVSGNGD-ISYEPWPTFDPSKLVLDELEIVVQING  746
            + +YA GF++++A FAPHLGEEL + ++++G+ ISY PWP++D SKLV +++EIVVQI+G
Sbjct  722  FSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKG  781

Query  747  KVRAKFVAPNNLPEDELKALVYDQAQVQKNLEGM  780
            KV+AK+V +++L+ +EL+ +   + +VQ ++ G 
Sbjct  782  KVKAKLVVAKDLSREELQEVALANEKVQAEIAGK  815

381) leuS in NC_021354


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  870 bits (3294),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 497/814 (62%), Positives = 634/814 (78%), Gaps = 37/814 (4%)

Query  2    YNHLKIEKKWQNYWDEHETFKTDVHNFDLPKYYVLDMFPYPSGNGLHVGHPRGYTATDVI  61
            Y+H  IE KWQ +W +++TFKT+ +    PK+Y LDMFPYPSG GLHVGHP GYTATD++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDA-SKPKFYALDMFPYPSGAGLHVGHPEGYTATDIL  62

Query  62   ARYKRMNGFNVLHPMGWDAFGLPAEQFALKTGNHPNEFTKQNIDHFTDQIKSLGLSYDWS  121
            +R+KR +G NVLHPMGWDAFGLPAEQ+A+ TGN+P EFT +NI +F  QI++LG+SYDW 
Sbjct  63   SRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWD  122

Query  122  REISTTDPGYYKWTQWIFTKLYDMGLAYVDEKPVNFCPELGTVLANEEVI-DGKSEVGGF  180
            RE++TTDP YYKWTQWIFTKLY+ GLAY  E PVN   ELGT +ANEEV+ DG SE GG+
Sbjct  123  REVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGY  182

Query  181  DVIRMPMRQWVLKITEYADRLLEDLDLVEWPDSTKEMQINWIGRSEGSNVIFKIADHDKE  240
             V+R PMRQW+LKIT YA+RLLEDL+ V+WP+S K+MQ NWIG+S G+NV FK+ D DK+
Sbjct  183  PVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  241  FTVFTTRADTLFGNTYCVLAPEHPFVKEITTAENIDEVNAYVEKVLHKSDLERTELNKEK  300
            FTVFTTR+DTLFG TY VLAPEH++V  ITT+++ + V  Y  +   KSDL RT+L KEK
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEK  302

Query  301  SGVFTGAYAINPVNGKKVPIYIADYVLAAYGTGAIMAVPAHDTRDFEFAKKYNLEIIPVI  360
            +GV TG+YAINPVNGK +P+ IADYVLA+YGTGAIMAVPAHD RD EFAK++NL+IIPV+
Sbjct  303  TGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL  362

Query  361  EGGDIAVEAYTGDGIHINSGFLDGMGKDEAIETMQSWLVENGYGEAKTTYKLRDWLFSRQ  420
            EGG++   A+T DG+HINS+FLDG++K  AI  M  WL  +G G+ + TY+LRDWLFSRQ
Sbjct  363  EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQ  422

Query  421  RYWGEPIPIVHLEDGTMRTVEIDELPLELPEVEHYKPASDGQSPLANAGDWLDVTFADGT  480
            RYWGEPIPI+H EDGT  +V   ELPL LP   + +P++ G+SPLAN  DWL+VT  DG 
Sbjct  423  RYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGV  482

Query  481  KGRRETNTMPQWAGSCWYYLRYIDPENNEAIGDPELLKHWMPVDLYMGGSEHAVLHLLYA  540
            KGRRETNTMPQWAGS WYYLRYIDP+N E ++D ELLK+W+PVD+Y+GG+EHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  541  RFWHKVLFDLGVVDTKEPFGKLYHQGMILGAN----------------------------  572
            RFWHKVL+DLGVV TKEPF KL++QGMILG++                            
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  573  -----NEKMSKSRGNVVNPDDIVESHGADALRVYEMFMGPLDGAIAWSTRGLDGIRKWLD  627
                   KMSKS  NVVNPDD+VE  GAD+LRVYEMFMGPLD++IAWS  GL+G RK LD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  628  RVYRLMVESDKISETNDGSLDFVYNQTVQKVTHDIETFGMNTAISQLMIFVNEAYKAETL  687
            RVYRL+   + I+E N G+LD VYN+TV+ VT++++    NTAI+QLM+FVN A K + L
Sbjct  663  RVYRLITTKE-ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKL  721

Query  688  YKEYALGFIKMLACFAPHLGEELYEIVSGNGD-ISYEPWPTFDPSKLVLDELEIVVQING  746
            + +YA GF++++A FAPHLGEEL + ++++G+ ISY PWP++D SKLV +++EIVVQI+G
Sbjct  722  FSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKG  781

Query  747  KVRAKFVAPNNLPEDELKALVYDQAQVQKNLEGM  780
            KV+AK+V +++L+ +EL+ +   + +VQ ++ G 
Sbjct  782  KVKAKLVVAKDLSREELQEVALANEKVQAEIAGK  815

382) leuS in NC_008528


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  869 bits (3290),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 509/826 (62%), Positives = 638/826 (78%), Gaps = 50/826 (6%)

Query  22   YDHKAIEKRWQTYWDEHKTFKTAPETSGKPKYYVMNMFPYPSGQGLHVGHPESYTATDIM  81
            YDH AIE +WQ++W ++ TFKT+ ++S KPK+Y ++MFPYPSG GLHVGHPE+YTATDI+
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDAS-KPKFYALDMFPYPSGAGLHVGHPEGYTATDIL  62

Query  82   ARFNRMRGFNVLQPMGWDAFGLPAEQYAIKTGHNPADFTNENIKHFKKQVKSLGFSYDWD  141
            +RF+R +G NVL+PMGWDAFGLPAEQYA+ TG++PA+FT ENI +FK+Q+++LGFSYDWD
Sbjct  63   SRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWD  122

Query  142  REINTTDPEYYKWTQWIFEQLYKKGLAYEDEIMVNWAPDFPGGGIVVANEEVI-DGKTER  200
            RE+NTTDP+YYKWTQWIF +LY KGLAYE E+ VNW  ++   G  +ANEEV+ DG +ER
Sbjct  123  REVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEEL---GTAIANEEVLPDGTSER  179

Query  201  GSYPVYRVPMKQWVLRITKYAERLLSDLDDLDWPEAIKEQQRNWIGKSTGAAVFFKV-DG  259
            G+YPV R PM+QW+L+IT YAERLL DL+++DWPE+IK+ QRNWIGKSTGA V FKV D 
Sbjct  180  GGYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDT  239

Query  260  KSDYQVEVYTTRPDTLFGASYMVLAPEHDLVDKITTSECRADVDAYKAKIASKSDLERTD  319
              D+   V+TTRPDTLFGA+Y VLAPEH LVD ITTS+    V  YK + + KSDL RTD
Sbjct  240  DKDF--TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTD  297

Query  320  LNREKTGAFTGAYGINPVNGEKIPIWIADYVLSSYGTGAIMAVPAHDTRDYEFAKKFDLP  379
            L +EKTG  TG+Y+INPVNG  +P+WIADYVL+SYGTGAIMAVPAHD RD EFAK+F+L 
Sbjct  298  LAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLD  357

Query  380  IRQVIKGGDISKEAFTGDGTHINSAFLDVLDKKQAIEKIIDWLEEHDAGHKQVNYKLRDW  439
            I  V+ GG++   AFT DG HINS FLD LDK  AI K+++WLE ++ G+ +V Y+LRDW
Sbjct  358  IIPVLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDW  417

Query  440  IFSRQRYWGEPIPVIHWEDGKQTLVPESELPLRLPHLNQDQMKPSGTGESPLANAKSWLE  499
            +FSRQRYWGEPIP+IHWEDG  T VPESELPL LP     +++PSGTGESPLAN   WLE
Sbjct  418  LFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLP--VTKDIRPSGTGESPLANVTDWLE  475

Query  500  VTRQDGVKGRRETNTMPQWAGSSWYFLRYIDPHNDKVLADPEKLKYWMNVDLYVGGAEHA  559
            VTR+DGVKGRRETNTMPQWAGSSWY+LRYIDPHN   LAD E LK W+ VD+YVGGAEHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  560  VLHLLYARFWHKFLYDLGIVPTKEPFQKLVNQGMILGTN---------------------  598
            VLHLLYARFWHK LYDLG+VPTKEPFQKL NQGMILGT+                     
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSF  595

Query  599  ------------HEKMSKSKGNVVNPDEIVDSYGADALRVYEMFMGPLTQSKPWSTESLA  646
                          KMSKS  NVVNPD++V+ YGAD+LRVYEMFMGPL  S +WS E+L 
Sbjct  596  FHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLE  655

Query  647  GIRRYLDRVWRIFTSDGDGINPIIVSENDHKLDKIFNQTVKKVTEDYAAMRFNTAISQMM  706
            G R++LDRV R++T+        I  EN   LDK++N+TVK VTE+   M+FNTAI+Q+M
Sbjct  656  GSRKFLDRVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLM  709

Query  707  VFINETFKAEKLPKKYMNAFLQLLNPVAPHITEELWQRM-GHQETIAYATWPTYDESQII  765
            VF+N + K +KL   Y ++F+QL+ P APH+ EELWQ + +  E+I+Y  WP+YDES+++
Sbjct  710  VFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLV  769

Query  766  EKQIEMAVQINGKVRAKINTPVDISRDELAKMATDNPDVKKQVADK  811
            E+++E+ VQI+GKV+AK+  + D+SR+EL  +A  N  V+ ++A+K
Sbjct  770  ENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGK  815

383) leuS in NC_008530


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  868 bits (3288),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 514/791 (65%), Positives = 630/791 (80%), Gaps = 45/791 (5%)

Query  2    YNHKTVEKKWQKYWAEHDTFKTGNDPKKKNYYALDMFPFPSGKGLHVGHPEGYTATDIIS  61
            Y+H ++E KWQ +WA+++TFKTG D+ K ++YALDMFP+PSG GLHVGHPEGYTATDI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  62   RMKRAQGYNVLHPMGWDAFGLPTEQYALKTGEDPEKVTKENIANFKKQLNKLGFSYDWDR  121
            R KRAQG NVLHPMGWDAFGLP+EQYA+ TG+DP   T ENIANFK+Q+N LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  122  EVTTSDPNYYKWTQWVFEQMYKKGLAYEAEVPVNWSPDLGTVVANEEIV-DGKTERGGYP  180
            EV T+DPNYYKWTQW+F ++Y KGLAYEAEVPVNW  +LGT +ANEE++ DG +ERGGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  181  VYRRNMRQWMLKMTAYAdrlledlddldWPEPVKEMQRNWIGRSEGAQVTFKVKDSDKTF  240
            V R+ MRQWMLK+TAYA+RLLEDL+++DWPE++K+MQRNWIG+S GA+VTFKVKD+DK F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  DVFTTRPDTLFGVSYTVLAPESKLVQEITTPEQKAAVDSYIKKIESKSDLERTDLNKDKT  300
             VFTTRPDTLFG +Y+VLAPE  LV+ ITT++Q  AV  Y ++   KSDL RTDL K+KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  301  GVFTGAYAINPVNGKEVPVWISDYVLASYGTGAVMAVPAHDDRDYAFATKFGLPINRVIE  360
            GV TG+YAINPVNGKE+PVWI+DYVLASYGTGA+MAVPAHD+RD  FA +F L I  V+E
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  361  GGDLEKEAFTGNGKHINSDFLDGLDNEEAKKRMIEWLEDHNAGQKKVNYKLRDWDFSRQR  420
            GG++E  AFT +G HINSDFLDGLD+  A  +M+EWLE +  G+ +V Y+LRDW FSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  421  YWGEPIPVIHWEDGTTSLVPEDELPLRLPHATDIKPSGTPESPLANLTDWVNVVDKNGRK  480
            YWGEPIP+IHWEDGT++ VPE ELPL LP + DI+PSGT ESPLAN+TDW++V   +G K
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  481  GKRETNTMPNWAGSSWYYLRYIDPHNDKELADYDLLKKWLPVDLYIGGAEHAVRHLLYAR  540
            G+RETNTMP+WAGSSWYYLRYIDPHN   LAD +LLK+WLPVD+Y+GGAEHAV HLLYAR
Sbjct  484  GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYAR  543

Query  541  FWHKVLYDLGVVPTKEPFQRLYNQGLIL--------------------------------  568
            FWHKVLYDLGVVPTKEPFQ+L+NQG+IL                                
Sbjct  544  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEE  603

Query  569  --KNHEKMSKSKGNVVNPDDVIDEYGADSLRMYEMFMGPLDASIDWDDNGPASTKKFLDR  626
              +   KMSKS  NVVNPDDV+++YGAD+LR+YEMFMGPLDASI W ++G  +++KFLDR
Sbjct  604  LEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR  663

Query  627  VWRLFVNDLDLKAIPQERIVDKNDGELDKVYAETVKKVTEDFDALHFNTAISQMMVFINA  686
            V RL         I    I + N G LDKVY ETVK VTE+ D + FNTAI+Q+MVF+NA
Sbjct  664  VYRL---------ITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNA  714

Query  687  AQKAKTIPREYAEGFVKLLAPVAPHMMEEIWQVF-GHDESISYAKWPEYDPAKLVESTVE  745
            A+K   +  +YA GFV+L+AP APH+ EE+WQ + + +ESISY  WP YD +KLVE+ VE
Sbjct  715  ANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVE  774

Query  746  IMVQVNGKLRG  756
            I+VQ++GK+++
Sbjct  775  IVVQIKGKVKA  785

384) leuS in NC_012673


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  868 bits (3286),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 518/834 (63%), Positives = 650/834 (78%), Gaps = 37/834 (4%)

Query  2    LSYFKHQEIEPKWQKRWEEKEAFKTTEDPEKDCFYVLDMFPYPSGAGLHVGHPEGYTATD  61
            ++++ H  IEPKWQ  W ++++FKT  D+ K  FY LDMFPYPSGAGLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  62   IIARMKRMQGYNVLHPIGWDAFGLPAEQYALDTGNDPREFTARNIETFRRQLKELGFSYD  121
            I++R KR QG NVLHP+GWDAFGLPAEQYA+DTGNDP EFTA NI  F+RQ++ LGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  122  WDREISTTDPKYYKWTQWIFTQLFERGLAYVDEVAVNWCPALGTVLANEEVI-DGLSERG  180
            WDRE++TTDP+YYKWTQWIFT+L+E+GLAY  EV+VNW   LGT +ANEEV+ DG SERG
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  181  NHPVYRVPMKQWVLRITEYAERLLEDLEGLDWPESVKEMQRNWIGKSVGAEVDFKVDGHD  240
              PV R PM+QW+L+IT YAERLLEDLE +DWPES+K+MQRNWIGKS GA+V FKV + D
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  241  KIVTVFTTRPDTLHGATYVTLAPEHPFTKVITTPEQSTAVEAYIEEVSKKTDLERTDLAK  300
            K  TVFTTRPDTL GATY  LAPEH++   ITT++Q+ AV  Y  + S K+DL RTDLAK
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  301  EKTGVFTGAYAINPVNGEKLPIWTADYVLSTYGTGAVMAVPGHDERDYEFAKTFDLPIRE  360
            EKTGV TG+YAINPVNG  +P+W ADYVL++YGTGA+MAVP+HDERD EFAK F+L I  
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  361  VVKGGNVEEAAYVEDGEHVNSGSLNGLNKADAIKTIIEELEASGTGRAKTTYRLRDWLFS  420
            V+ GGNVEEAA+ EDG H+NS+ L+GL+KA AI  ++E LEA G G  + TYRLRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  421  RQRYWGEPIPVVHMEDGTMKTvpveelplelpIIDEIKPSGTGESPLANAEEWLTYTDPV  480
            RQRYWGEPIP++H EDGT  +VP  ELPL LP+  +I+PSGTGESPLAN  +WL      
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE-VTRE  479

Query  481  TGEKGRRETNTMPQWAGSCWYYIRYIDPDNEEMIADPEKLKRWLPVDLYIGGTEHAVLHL  540
             G KGRRETNTMPQWAGS WYY+RYIDP+N E +AD E LK+WLPVD+Y+GG+EHAVLHL
Sbjct  480  DGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHL  539

Query  541  LYARFWHKVLFDIGVVPTSEPFQKLYNQGMILG---------------------------  573
            LYARFWHKVL+D+GVVPT EPFQKL+NQGMILG                           
Sbjct  540  LYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVE  599

Query  574  ------ENNEKMSKSRGNVVNPDDIVKSHGADTLRLYEMFMGPLDAAIAWSTNGLDGARR  627
                  +   KMSKS  NVVNPDD+V   GADTLR+YEMFMGPLDA+IAWS +GL+G+R+
Sbjct  600  TGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRK  659

Query  628  FLDRVWRLFDQTNFADVAPTADFERTYHQTVKKVTEDYEALRFNTAISQLMVFVNEANKQ  687
            FLDRV RL+   ++++   ++ +++ Y++TVK VTE+ + ++FNTAI+QLMVFVN ANK+
Sbjct  660  FLDRVYRLITTKEITE-ENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKE  718

Query  688  ETLPKSQMVDFIKMLSPVAPHLSEELWEKMGMTEE-LTYAAWPTYDESKLVSDTIEVVIQ  746
            + L      +F+++++P APHL+EELW+ +  + E ++Y +WP+YDESKLV + +E+V+Q
Sbjct  719  DKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQ  778

Query  747  VNGKLRAKMHVSRDASKEALEAEALGNERVQEFTEGKTVRKVIVVPGKLVNIVV  800
            ++GK++AK+ V++D S+E L+  AL+NE+VQ    GK + KVI VP KLVNIV+
Sbjct  779  IKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

385) leuS in NC_007350


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  866 bits (3281),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 532/837 (64%), Positives = 675/837 (81%), Gaps = 42/837 (5%)

Query  3    YSHNEIEKKWQDYWEANKTFKTSDNLGQKKFYALDMFPYPSGAGLHVGHPEGYTATDIIS  62
            Y H  IE KWQ +W  N TFKT+ + ++ KFYALDMFPYPSGAGLHVGHPEGYTATDI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRMLGYNVLHPMGWDAFGLPAEQYALDTGNDPREFTKENIQTFKRQIKELGFSYDWDR  122
            R+KR  G NVLHPMGWDAFGLPAEQYA+DTGNDP EFT ENI  FKRQI+ LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVNTTDPEYYKWTQWIFIQLYNKGLAYVDEVAVNWCPALGTVLSNEEVI-DGVSERGGHP  181
            EVNTTDP+YYKWTQWIF +LY+KGLAY  EV+VNW   LGT ++NEEV+ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VYRRPMKQWVLKITEYAdrlledldeldWPESLKDMQRNWIGRSEGASVAFDVKDYNEQI  241
            V R+PM+QW+LKIT YA+RLLEDL+E+DWPES+KDMQRNWIG+S GA+V+F VKD + ++
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  EVFTTRPDTIYGASFLVLSPEHELVDLITTEDNKDDVEAYQKEAAKKSDLERTGLSKEKS  301
             VFTTRPDT++GA++ VL+PEH LVD ITT D+ + V  Y+++A+ KSDL RT+L+KEK+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAVNPLSGQQVPIWIADYVLSTYGTGAVMAVPSGDQRDYEFAKTFDLPIIEVIE  361
            GV TG+YA+NP++G+++P+WIADYVL++YGTGA+MAVP+ D+RD EFAK F+L II V+E
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGDMSKEAYTGDGPHINSGELNGLYNeaaiekaielleNKNAGTRKVNYKLRDWLFSRQR  421
            GG++   A+T DG HINS+ L+GL + +AI K +E LE    G  +V Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPVIHWEDGSMttvpedelplllpetdeIKPSGTGESPLANIDEFVNVVDEATGM  481
            YWGEPIP+IHWEDG+ T+VPE ELPL+LP T +I+PSGTGESPLAN+ + ++V  E  G+
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED-GV  482

Query  482  KGRRETNTMPQWAGSCWYYLRYIDPDNEQMLADPEKLKHWLPVDLYIGGVEHAVLHLLYA  541
            KGRRETNTMPQWAGS WYYLRYIDP+N + LAD E LK+WLPVD+Y+GG EHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKVLFDLGVVPTKEPFQKLFNQGMILG------------------------------  571
            RFWHKVL+DLGVVPTKEPFQKLFNQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---EGNEKMSKSKGNVINPDDIVKSHGADTLRLYEMFMGPLDAAIAWSENGLDGSRRFLD  628
               ++  KMSKS  NV+NPDD+V   GADTLR+YEMFMGPLDA+IAWSE+GL+GSR+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RIWRLLITEDGSISNKVVNNHSKALDKSYHQTVKKVTEDYNSLNFNTAISQLMVFINDCY  688
            R+ RL+ T +      + +++S ALDK Y++TVK VTE+ + ++FNTAI+QLMVF+N   
Sbjct  663  RVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  689  KAEEIYKPYIEGFIKMLAPIAPHISEELWSRL-GHDETITYQPWPSYDEALLVDDEIEIV  747
            K + ++  Y  GF++++AP+APH++EELW  L + +E+I+Y PWPSYDE+ LV++++EIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  748  VQVNGKVRAKINVSKDIAKEEMEQIALDNEHVKSEIEGKDIKKVIAVPKKLVNIVAK  804
            VQ++GKV+AK+ V+KD+++EE++++AL NE V++EI GKDI KVIAVP+KLVNIV K
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

386) leuS in NC_010556


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  865 bits (3274),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 522/834 (63%), Positives = 660/834 (80%), Gaps = 39/834 (4%)

Query  3    YNHREIEPKWQARWEQDNAFVTTEDPEKEGFYALDMFPYPSGAGLHVGHPEGYTATDILA  62
            Y+H  IEPKWQA W ++++F T  D+ K  FYALDMFPYPSGAGLHVGHPEGYTATDIL+
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMKRMQGYNVLHPMGWDAFGLPAEQYALDTGNDPREFTAQNIETFKRQLKDLGFSYDWDR  122
            R KR QG NVLHPMGWDAFGLPAEQYA+DTGNDP EFTA+NI  FKRQ++ LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EINTTDPKYYKWTQWIFTKLYEQGLAFVDEVAVNWCPALGTVLANEEVI-DGLSERGNHP  181
            E+NTTDP+YYKWTQWIFTKLYE+GLA+  EV+VNW   LGT +ANEEV+ DG SERG  P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VVRVPMRQWVLKITEYAdrlledldeldWPESVKEMQRNWIGKSEGAEIDFTIDGHKKQV  241
            VVR PMRQW+LKIT YA+RLLEDL+E+DWPES+K+MQRNWIGKS GA++ F + +  K+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  TVFTTRPDTVFGATYLVLAPEHPFVTDITTEDHEEAVKAYIASVQTKSDLERTDLAKEKT  301
            TVFTTRPDT+FGATY VLAPEH++V  ITT D+ EAV  Y      KSDL RTDLAKEKT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAFAVNPISGERLPIWIADYVLATYGTGAIMAVPAHDERDHEFAKQFDLPIIEVVK  361
            GV TG++A+NP++G  +P+WIADYVLA+YGTGAIMAVPAHDERD EFAKQF+L II V+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGNVDEVAYTGEGEHVNSQMLDGLSKQeaietiiaeletNQVGRKKITFRLRDWLFSRQR  421
            GGNV+E A+T +G H+NS+ LDGL K  AI  ++  LE++ VG  ++T+RLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPVVHMEDGTMKTLDKSELPLELPMIPEIKPSGTGESPLALAEDWLDYTDPVTGL  481
            YWGEPIP++H EDGT  ++  SELPL LP+  +I+PSGTGESPLA   DWL+      G+
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE-VTREDGV  482

Query  482  KGRRETNTMPQWGGSCWYYLRFIDPHNEEAIADPEKLKYWLPVDIYIGGAEHAVLHLLYA  541
            KGRRETNTMPQW+GS WYYLR+IDPHN E +AD E LK WLPVDIY+GGAEHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKVLYDIGVVPTKEPFQKLYNQGMILG------------------------------  571
            RFWHKVLYD+GVVPTKEPFQKL+NQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---ENNEKMSKSRGNVINPDEIVKSHGADTLRLYEMFMGPLDASVSWSENGLDGARRFLD  628
               +   KMSKS  NV+NPD++V   GADTLR+YEMFMGPLDAS++WSE+GL+G+R+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RVWRLFERTADIQDVTTVDADFERVYHQTVKKVTEDFTNIQFNTGISQLMVFVNEANKQP  688
            RV RL+      ++ +   + +++VY++TVK VTE+  +++FNT+I+QLMVFVN ANK+ 
Sbjct  663  RVYRLITTKEITEENS---GALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKED  719

Query  689  VLPRHFLRGFIQLLTPVAPHLGEELWEQL-GFEDTLTYAAWPTFDETKLVSDTMEFVIQV  747
             L  ++ +GF+QL++P APHLGEELW+ L +  ++++Y +WP++DE+KLV + +E+V+Q+
Sbjct  720  KLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQI  779

Query  748  NGKVRSKLVISMEATKEEIEALAFADEKTQEWIGDKTVRKVIVVPKKLINIVAN  801
            +GKV++KLV++ + ++EE++ +A+A+EK Q  I++K + KVI VP+KL+NIV +
Sbjct  780  KGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

387) leuS in NC_015978


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  865 bits (3276),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 498/823 (61%), Positives = 649/823 (79%), Gaps = 44/823 (5%)

Query  3    YDHAKVEKKWQHYWEENKTFRTSDKTEKEKYYVLDMFPYPSGQGLHVGHPEGYTATDIMA  62
            YDH+ +E KWQ +W +N TF+T+  + K K+Y LDMFPYPSG GLHVGHPEGYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RFERMQGKNVLHPIGWDAFGLPAEQYAMKTGHNPREFTNQNIDNFRRQIKSLGFSYDWDR  122
            RF R QG NVLHP+GWDAFGLPAEQYAM TG++P EFT +NI NF+RQI++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVNTTDPKYYKWTQWIFEKLYEKGLAYEDEIEVNWAPDLMGGTVVANEEVV-NGKTERGG  181
            EVNTTDP+YYKWTQWIF KLYEKGLAYE E+ VNW  +L  GT +ANEEV+ +G +ERGG
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEEL--GTAIANEEVLPDGTSERGG  181

Query  182  FPVYRKPMKQWVLRITAYAdrllddlddvdWPESVKQMQRNWIGRSVGASINFNVDEHPD  241
            +PV RKPM+QW+L+ITAYA+RLL+DL++VDWPES+K+MQRNWIG+S GA++ F+V +  D
Sbjct  182  YPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKD-TD  240

Query  242  ESIEVFSTRADTLFGATYIVLAPESDIVDKIVTPEQKAAIDEYRQKIASKSDLERTDLNK  301
              + VF+TR+DTLFGATY VLAPE  +VD I T++Q  A+ +Y+++ + KSDL RTDL K
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  302  DKSGVFTGAYAINPVNGAKLPIWIGDYVLSSYGTGAIMAVPAHDDRDYEFAKKSKLPIIP  361
            +K+GV TG+YAINPVNG  +P+WI+DYVL+SYGTGAIMAVPAHD+RD EFAK+ +L IIP
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  362  VIEGGDIEKEPYTGDGVHINSGFLDGLGKKDAINTMIEWLQTHHAGDKKVNYKLRDWIFS  421
            V+EGG++E  ++T DG+HINS+FLDGL+K  AI  M+EWL+++  G+ +V Y+LRDW+FS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  422  RQRYWGEPIPVINWDDGTKSLVPEDELPLRLPKTDDIKSSGTGESPLANLKDWVNVTDKN  481
            RQRYWGEPIP+I+W+DGT + VPE ELPL LP T DI++SGTGESPLAN+ DW++VT  +
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  482  GRHGKRETNTMPQWAGSSWYYLRYIDPKNDKMLADPKKLDYWLPIDLYVGGAEHAVLHLL  541
            G  G+RETNTMPQWAGSSWYYLRYIDP N   LAD   L  WLP+D+YVGGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  542  YARFWHKFLYDLGVVPTKEPFQRLVNQGMILGTN--------------------------  575
            YARFWHK LYDLGVVPTKEPFQ+L NQGMILGT+                          
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  576  -------HEKMSKSKGNVVNPDDIVNEYGADTLRLYEMFMGPLTESKPWSTEGIVGANRW  628
                     KMSKS  NVVNPDD+V++YGADTLR+YEMFMGPL  S +WS EG+ G+ + 
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  629  IKRVWRMYLNDDNSTSDMLIADNDGKLDKVYNQTVKKVTDDIEKMRFNTAISQMMVFVNE  688
            + RV R+       T+  +  +N G LDKVYN+TVK VT+++++M+FNTAI+Q+MVFVN 
Sbjct  661  LDRVYRL------ITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNA  714

Query  689  VYKNKTLPKRYAEGFIKLLSPITPHMAEEIWQQL-GHKDTIAYAEWPTYDESKLKDDQAE  747
              K+  L   YA GF++L++P++PH++EE+WQ L +  ++I+Y  WP+YDESKL +++ E
Sbjct  715  ANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVE  774

Query  748  LVVQINGKVRAHITVAVGTSKDDIEKIALADDNIKNNLQNKTV  790
            +VVQI+GKV+A + VA + S+++++ +ALA+++++ ++  K +
Sbjct  775  IVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDI  817

388) leuS in NC_015690


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  859 bits (3252),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 520/840 (62%), Positives = 659/840 (79%), Gaps = 46/840 (5%)

Query  44   YNPLAIEPKWQQYWDQNKTFKVLDDESKPKFYALDMFPYPSGAGLHVGHPEGYTATDIVS  103
            Y+  AIEPKWQ +W +N TFK   D SKPKFYALDMFPYPSGAGLHVGHPEGYTATDI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  104  RYKRMRGYNVLHPMGWDAFGLPAEQHALDTGQHPREITVKNINNFRRQIKSLGFSYDWDR  163
            R+KR +G NVLHPMGWDAFGLPAEQ A+DTG++P E+T  NI NF+RQI++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  164  EISTTDPDYYKWTQWIFIQLYNKGLAYVDEVPVNWCPALGTVLANEEVI-DGLSERGGHP  222
            E++TTDP+YYKWTQWIF +LY+KGLAY  EVPVNW   LGT +ANEEV+ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  223  VIRKPMRQWVLRITEYAerlledleeldWSESIKDMQRHWIGKSKGAEVTFAIDGHDGEG  282
            V+RKPMRQW+L+IT YAERLLEDLEE+DW+ESIKDMQR+WIGKS GA+VTF + + D + 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKD-  242

Query  283  LKVFTTRPDTLFGATYCVLAPEHELVERITAGEQSAAVKEYQERAARKSDLERTDLAKEK  342
            + VFTTRPDTLFGATY VLAPEH LV+ IT+++Q+ AV +Y+ +A+ KSDL RTDLAKEK
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEK  302

Query  343  TGVFTGAYAVNPVSGARLPIWIADYVLAGYGTGAIMAVPGHDQRDWEFAKQYDLPILEVV  402
            TGV TG+YA+NPV+G  +P+WIADYVLA+YGTGAIMAVP+HD+RDWEFAKQ++L I+ V+
Sbjct  303  TGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL  362

Query  403  SGGDVEKEAYAGDGPHVNSGFLDGLNNEQGIAKMIEWLEQSGKGQGKVTYRLRDWLFSRQ  462
             GG+VE  A++ DG H+NS+FLDGL++  +IAKM+EWLE  G G+ +VTYRLRDWLFSRQ
Sbjct  363  EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQ  422

Query  463  RYWGEPIPILHLEDGTMKTVPEDQLPLLLPEVDEIKPSGTGESPLAVVTDWVNTVDPETG  522
            RYWGEPIPI+H EDGT  +VPE +LPL+LP   +I+PSGTGESPLA VTDW++ V  E G
Sbjct  423  RYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE-VTREDG  481

Query  523  KPARRETNTMPQWAGSCWYYLRFIDPKNDDALCSKELQRKWLPVDLYIGGAEHAVLHLLY  582
              +RRETNTMPQWAGS WYYLR+IDP N + L   EL ++WLPVD+Y+GGAEHAVLHLLY
Sbjct  482  VKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLY  541

Query  583  ARFWHKVLYDLGVVETKEPFYKLVNQGMIL-----------------------------G  613
            ARFWHKVLYDLGVV TKEPF KL NQGMIL                             G
Sbjct  542  ARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETG  601

Query  614  ENME----KMSKSRGNVINPDEIVNEYGADTLRLYEMFMGPLEATKPWNTNGVDGAYRFL  669
            E++E    KMSKS  NV+NPD++V++YGADTLR+YEMFMGPL+A+ +W+ +G++G+ +FL
Sbjct  602  EELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFL  661

Query  670  SRVWRLFISEDGSLSAKITDSADAGTDAFKRIWHRTIKKVTEDLEALRFNTAISQLMIFV  729
             RV RL+ +          + ++  ++A+ ++ + T+K VTE+++ ++FNTAI+QLM+FV
Sbjct  662  DRVYRLITT---------KEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFV  712

Query  730  NEAYKTETLPKAAMEQFAQMLSPIAPHLAEELWEKLGHSG-TISYASWPVYEEAWTVDNE  788
            N A K + L       F Q+++P+APHL+EELW+ L  SG +ISY +WP Y+E+  V+N+
Sbjct  713  NAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVEND  772

Query  789  VEIVVQVNGKiaeratiaadadeaaMQEFALGLDKVKEATAGKTVRKIIAVKGKLVNIVV  848
            VEIVVQ++GK+  +  +A D     +QE AL+ +KV+   AGK + K+IAV  KLVNIV+
Sbjct  773  VEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

389) PM3016_5616 in NC_016935


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  858 bits (3251),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 520/840 (62%), Positives = 659/840 (79%), Gaps = 46/840 (5%)

Query  11   YNPLAIEPKWQQYWDQNKTFKVLDDESKPKFYALDMFPYPSGAGLHVGHPEGYTATDIVS  70
            Y+  AIEPKWQ +W +N TFK   D SKPKFYALDMFPYPSGAGLHVGHPEGYTATDI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  71   RYKRMRGYNVLHPMGWDAFGLPAEQHALDTGQHPREITVKNINNFRRQIKSLGFSYDWDR  130
            R+KR +G NVLHPMGWDAFGLPAEQ A+DTG++P E+T  NI NF+RQI++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  131  EISTTDPDYYKWTQWIFIQLYNKGLAYVDEVPVNWCPALGTVLANEEVI-DGLSERGGHP  189
            E++TTDP+YYKWTQWIF +LY+KGLAY  EVPVNW   LGT +ANEEV+ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  190  VIRKPMRQWVLRITEYAerlledleeldWSESIKDMQRHWIGKSKGAEVTFAIDGHDGEG  249
            V+RKPMRQW+L+IT YAERLLEDLEE+DW+ESIKDMQR+WIGKS GA+VTF + + D + 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKD-  242

Query  250  LKVFTTRPDTLFGATYCVLAPEHELVERITAGEQSAAVKEYQERAARKSDLERTDLAKEK  309
            + VFTTRPDTLFGATY VLAPEH LV+ IT+++Q+ AV +Y+ +A+ KSDL RTDLAKEK
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEK  302

Query  310  TGVFTGAYAVNPVSGARLPIWIADYVLAGYGTGAIMAVPGHDQRDWEFAKQYDLPILEVV  369
            TGV TG+YA+NPV+G  +P+WIADYVLA+YGTGAIMAVP+HD+RDWEFAKQ++L I+ V+
Sbjct  303  TGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL  362

Query  370  SGGDVEKEAYAGDGPHVNSGFLDGLNNEQGIAKMIEWLEQSGKGQGKVTYRLRDWLFSRQ  429
             GG+VE  A++ DG H+NS+FLDGL++  +IAKM+EWLE  G G+ +VTYRLRDWLFSRQ
Sbjct  363  EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQ  422

Query  430  RYWGEPIPILHLEDGTMKTVPEDQLPLLLPEVDEIKPSGTGESPLAVVTDWVNTVDPETG  489
            RYWGEPIPI+H EDGT  +VPE +LPL+LP   +I+PSGTGESPLA VTDW++ V  E G
Sbjct  423  RYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE-VTREDG  481

Query  490  KPARRETNTMPQWAGSCWYYLRFIDPKNDDALCSKELQRKWLPVDLYIGGAEHAVLHLLY  549
              +RRETNTMPQWAGS WYYLR+IDP N + L   EL ++WLPVD+Y+GGAEHAVLHLLY
Sbjct  482  VKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLY  541

Query  550  ARFWHKVLYDLGVVETKEPFYKLVNQGMIL-----------------------------G  580
            ARFWHKVLYDLGVV TKEPF KL NQGMIL                             G
Sbjct  542  ARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETG  601

Query  581  ENME----KMSKSRGNVINPDEIVNEYGADTLRLYEMFMGPLEATKPWNTNGVDGAYRFL  636
            E++E    KMSKS  NV+NPD++V++YGADTLR+YEMFMGPL+A+ +W+ +G++G+ +FL
Sbjct  602  EELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFL  661

Query  637  SRVWRLFISEDGSLSAKITDSADAGTDAFKRIWHRTIKKVTEDLEALRFNTAISQLMIFV  696
             RV RL+ +          + ++  ++A+ ++ + T+K VTE+++ ++FNTAI+QLM+FV
Sbjct  662  DRVYRLITT---------KEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFV  712

Query  697  NEAYKTETLPKAAMEQFAQMLSPIAPHLAEELWEKLGRSG-TISYASWPVYEEAWTVDNE  755
            N A K + L       F Q+++P+APHL+EELW+ L  SG +ISY +WP Y+E+  V+N+
Sbjct  713  NAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVEND  772

Query  756  VEIVVQVNGKiaeratiaadadeaaMQEFALGLDKVKEATAGKTVRKIIAVKGKLVNIVV  815
            VEIVVQ++GK+  +  +A D     +QE AL+ +KV+   AGK + K+IAV  KLVNIV+
Sbjct  773  VEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

390) B2K_28610 in NC_017672


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  858 bits (3250),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 519/840 (62%), Positives = 660/840 (79%), Gaps = 46/840 (5%)

Query  11   YNPLAIEPKWQQYWDQNKTFKVLDDESKPKFYALDMFPYPSGAGLHVGHPEGYTATDIVS  70
            Y+  AIEPKWQ +W +N TFK   D SKPKFYALDMFPYPSGAGLHVGHPEGYTATDI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  71   RYKRMRGYNVLHPMGWDAFGLPAEQHALDTGQHPREITVKNINNFRRQIKSLGFSYDWDR  130
            R+KR +G NVLHPMGWDAFGLPAEQ A+DTG++P E+T  NI NF+RQI++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  131  EISTTDPDYYKWTQWIFIQLYNKGLAYVDEVPVNWCPALGTVLANEEVI-DGLSERGGHP  189
            E++TTDP+YYKWTQWIF +LY+KGLAY  EVPVNW   LGT +ANEEV+ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  190  VIRKPMRQWVLRITEYAerlledleeldWSESIKDMQRHWIGKSKGAEVTFAIDGHGGEA  249
            V+RKPMRQW+L+IT YAERLLEDLEE+DW+ESIKDMQR+WIGKS GA+VTF + + + + 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKD-  242

Query  250  LKVFTTRPDTLFGATYCVLAPEHELVERITAGEQSAAVKEYQERAARKSDLERTDLAKEK  309
            + VFTTRPDTLFGATY VLAPEH LV+ IT+++Q+ AV +Y+ +A+ KSDL RTDLAKEK
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEK  302

Query  310  TGVFTGAYAVNPVSGARLPIWIADYVLAGYGTGAIMAVPGHDQRDWEFAKQYDLPILEVV  369
            TGV TG+YA+NPV+G  +P+WIADYVLA+YGTGAIMAVP+HD+RDWEFAKQ++L I+ V+
Sbjct  303  TGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL  362

Query  370  SGGDVEKEAYAGDGPHVNSGFLDGLNNEQGIAKMIEWLEQNGKGQGKVTYRLRDWLFSRQ  429
             GG+VE  A++ DG H+NS+FLDGL++  +IAKM+EWLE +G G+ +VTYRLRDWLFSRQ
Sbjct  363  EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQ  422

Query  430  RYWGEPIPILHLEDGTMKTVPEDQLPLLLPEVDEIKPSGTGESPLAVVTDWVNTVDPETG  489
            RYWGEPIPI+H EDGT  +VPE +LPL+LP   +I+PSGTGESPLA VTDW++ V  E G
Sbjct  423  RYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE-VTREDG  481

Query  490  KPARRETNTMPQWAGSCWYYLRFIDPKNDDALCSKELQRKWLPVDLYIGGAEHAVLHLLY  549
              +RRETNTMPQWAGS WYYLR+IDP N + L   EL ++WLPVD+Y+GGAEHAVLHLLY
Sbjct  482  VKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLY  541

Query  550  ARFWHKVLYDLGVVETKEPFYKLVNQGMIL-----------------------------G  580
            ARFWHKVLYDLGVV TKEPF KL NQGMIL                             G
Sbjct  542  ARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETG  601

Query  581  ENME----KMSKSRGNVINPDEIVNEYGADTLRLYEMFMGPLEATKPWNTNGVDGAYRFL  636
            E++E    KMSKS  NV+NPD++V++YGADTLR+YEMFMGPL+A+ +W+ +G++G+ +FL
Sbjct  602  EELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFL  661

Query  637  SRVWRLFISEDGSLSAKITDSADAGTDAFKRIWHRTIKKVTEDLEALRFNTAISQLMIFV  696
             RV RL+ +          + ++  ++A+ ++ + T+K VTE+++ ++FNTAI+QLM+FV
Sbjct  662  DRVYRLITT---------KEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFV  712

Query  697  NEAYKTETLPKAAMEQFAQMLSPIAPHLAEELWEKLGHSG-TISYASWPVYEEAWTVDNE  755
            N A K + L       F Q+++P+APHL+EELW+ L  SG +ISY +WP Y+E+  V+N+
Sbjct  713  NAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVEND  772

Query  756  VEIVVQVNGKiaeratiaadadeaaMQEFALGLDKVKEATAGKTVRKIIAVKGKLVNIVV  815
            VEIVVQ++GK+  +  +A D     +QE AL+ +KV+   AGK + K+IAV  KLVNIV+
Sbjct  773  VEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

391) leuS in NC_017668


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  856 bits (3240),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 551/837 (66%), Positives = 673/837 (81%), Gaps = 42/837 (5%)

Query  3    FDHKKIEKKWQKYWLDQKTFKTDSESEKKKFYALDMFPYPSGAGLHVGHPEGYTATDILS  62
            +DH  IE KWQ +W D+ TFKT++++ K KFYALDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMKRMQGYEVLHPIGWDAFGLPAEQYALDTGNDPEEFTAQNIQTFRRQIQELGFSYDWDR  122
            R KR QG +VLHP+GWDAFGLPAEQYA+DTGNDP EFTA+NI  F+RQI+ LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVNTTDPDYYKWTQWIFLKLYEKGLAYIDEVAVNWCPALGTVLANEEVI-DGKSERGDHP  181
            EVNTTDP+YYKWTQWIF KLYEKGLAY  EV+VNW   LGT +ANEEV+ DG SERG+ P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRPMKQWMLKITAYAdrllddledldWPESIKDMQRNWIGKSEGAEVTFHIEGDKGTF  241
            V R+PM+QWMLKITAYA+RLL+DLE++DWPESIKDMQRNWIGKS GA+VTF + +    F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  DVFTTRPDTLFGATYAVLAPEHPLVEKIVSPDHQDAVQTYVEKALNKSDLERTDLAKDKS  301
             VFTTRPDTLFGATYAVLAPEH+LV+ I ++D+ +AV  Y  +A  KSDL RTDLAK+K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGSYAINPINGEKLPIWVADYVLMSYGSGAIMAVPAHDERDYEFAQKFDLPIVPvve  361
            GV TGSYAINP+NG  +P+W+ADYVL SYG+GAIMAVPAHDERD EFA++F+L I+PV+E
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  ggnvneeAYTGDGKHINSDFLNGLDKDEAIDKSIEWLENNGRGKKQTTYRLRDWLFSRQR  421
            GGNV+E A+T DG HINSDFL+GLDK  AI K +EWLE +G G+ + TYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPIIHWEDGSvtpvpetelpvelpktteIKPSGTGESPLANINDWVNVVDPDTGM  481
            YWGEPIPIIHWEDG+ T+VPE+ELP+ LP T +I+PSGTGESPLAN+ DW++V   + G+
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT-REDGV  482

Query  482  KGRRETNTMPQWAGSCWYYLRYIDANNEQELGDYEKLKKWLPVDVYIGGAEHAVLHLLYA  541
            KGRRETNTMPQWAGS WYYLRYID++N + L+D E LK+WLPVD+Y+GGAEHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKVLYDAGVVPTKEPFQKLFNQGMILG------------------------------  571
            RFWHKVLYD GVVPTKEPFQKLFNQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---ENNEKMSKSKGNVVNPDDIVHTHGADTLRLYEMFMGPLDASVAWSTNGLDGArrfld  628
               +   KMSKS  NVVNPDD+V+  GADTLR+YEMFMGPLDAS+AWS +GL+G+R+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  rvfrlfvvdGELSDSIKQDVSEDKLEKVYHETVKKVTENFEALRFNTGISQMMVFINEGY  688
            RV+RL+      +  I ++ + + L+KVY+ETVK VTE+ + ++FNT+I+Q+MVF+N + 
Sbjct  663  RVYRLIT-----TKEITEE-NSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  689  KVEELPKSYVEGFVKLLSPVAPHLAEELWEKL-GHPETITYQQWPIFDEEKLVEDEVEIV  747
            K + L   Y  GFV+L++P APHL+EELW+ L +  E+I+Y  WP +DE KLVE++VEIV
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  748  VQVMGKVRAKMMVNQEASAEDLEKQALENENVQQWLEGKTVRKVIAVPGKLVNIVAN  804
            VQ+ GKV+AK++V ++ S E+L+  AL NE+VQ  + GK + KVIAVP KLVNIV +
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

392) Theco_2421 in NC_019897


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  855 bits (3236),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 528/838 (64%), Positives = 656/838 (79%), Gaps = 43/838 (5%)

Query  10   YDPRTIEPKWQAYWEKNKTFKTHDDTSKPKFYALDMFPYPSGSGLHVGHPEGYTATDIVA  69
            YD  +IEPKWQA+W  N TFKT  D+SKPKFYALDMFPYPSG+GLHVGHPEGYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  70   RYKRMRGYNVLHPMGWDAFGLPAEQHALNTGEHPRGFTEQNINNFRRQIKSLGFSYDWDR  129
            R+KR +G NVLHPMGWDAFGLPAEQ A++TG++P  FT +NI NF+RQI++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  130  EISTTDPEYYKWTQWIFLQLYKKGLAYVAEVPVNWCPALGTVLANEEVI-NGVSERGGHP  188
            E++TTDP+YYKWTQWIF +LY KGLAY AEVPVNW   LGT +ANEEV+ +G SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  189  VIRKPMRQWMLKITEYAerlledleeldWPESIKEMQRNWIGKSQGAEVTFAIDGHDASI  248
            V+RKPMRQWMLKIT YAERLLEDLEE+DWPESIK+MQRNWIGKS GA+VTF + + D  +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  249  TVFTTRPDTLFGATYCVLAPEHELVDKITTEAQREAVEAYRDAAARKSDLERTDLAKEKT  308
            TVFTTRPDTLFGATY VLAPEH LVD ITT  Q EAV  Y+  A+ KSDL RTDLAKEKT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  309  GVFTGAYAVNPVNGAKLPVWIADYVLGGYGTGAIMAVPAHDQRDWEFAKQYDLPIIEVVR  368
            GV TG+YA+NPVNG  +PVWIADYVL++YGTGAIMAVPAHD+RDWEFAKQ++L II V+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  369  GGDVTKEAFTGDGPHVNSGLLDGLHNEEAKAKMIEWLEREGKGRAKTTYRLRDWLFSRQR  428
            GG+V   AFT DG H+NS++LDGL++  A AKM+EWLE EG G  + TYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  429  YWGEPIPILHLEDGTMKPVpeedlplllpdldeIKPSGTGESPLANATDWVNTVDPETGL  488
            YWGEPIPI+H EDGT  +VPE +LPL+LP   +I+PSGTGESPLAN TDW++ V  E G+
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE-VTREDGV  482

Query  489  KARRETNTMPQWAGSCWYYLRYIDPHNDKELVSKEKEKYWLPVDLYIGGAEHAVLHLLYA  548
            K+RRETNTMPQWAGS WYYLRYIDPHN   L   E  K WLPVD+Y+GGAEHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  549  RFWHKVLYDIGVVSTKEPFRKLVNQGMILGTN----------------------------  580
            RFWHKVLYD+GVV+TKEPF+KL NQGMILGT+                            
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  581  -----NEKMSKSRGNVINPDDIVNEYGADTLRMYEMFMGPLEATKPWNTNGVEGTYRFLS  635
                   KMSKS  NV+NPDD+V++YGADTLR+YEMFMGPL+A+ +W+ +G+EG+ +FL 
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  636  RVWRLYIGEDGNLNPKIADGDADDAFKRTWHRTIKKVTEDYENLRFNTAISQLMIFVNDA  695
            RV RL       +  K    +  +A+ +  + T+K VTE+ ++++FNTAI+QLM+FVN A
Sbjct  663  RVYRL-------ITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAA  715

Query  696  YKAERLPRKAMNDFLQLLSPIAPHIAEELWERM-GHSDTITYEPWPEYDEAWTVDQEIEI  754
             K ++L     ++F+QL++P+APH++EELW+ + + +++I+Y PWP YDE+  V++++EI
Sbjct  716  NKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEI  775

Query  755  VVQVNGKIVDRVKVAADAPEDELERLAKESSRVQELTAGKTVRKIIVVKGKLVNIVAN  812
            VVQ++GK+  ++ VA D + +EL+ +A  + +VQ   AGK + K+I V  KLVNIV +
Sbjct  776  VVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

393) leuS in NC_010610


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  855 bits (3237),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 508/815 (63%), Positives = 633/815 (78%), Gaps = 43/815 (5%)

Query  3    YDHKAIEKKWQRYWKQHKTFKATLDKDQKKYYALDMFPYPSGQGLHVGHPEGYTATDVMS  62
            YDH AIE KWQ +W ++ TFK+  D  + K+YALDMFPYPSG GLHVGHPEGYTATD++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RLKRMQGFNVLHPMGWDAFGLPAEQYALKTGHNPADFTNQNVDHFRDQIQSLGFSYDWDR  122
            R+KR QG NVLHPMGWDAFGLPAEQYA+ TG++PA+FT +N+ +F+ QI++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVNTTDPNYYKWTQWIFEQLYKKGLAYEDEIMVNWAPDFMGGTVVANEEVVDGKTERGGY  182
            EVNTTDPNYYKWTQWIF +LY KGLAYE E+ VNW  + +G ++  +E + DG +ERGGY
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEE-LGTAIANEEVLPDGTSERGGY  182

Query  183  PVYRVPMRQWVLKITAYADRLIDDLDLVDWPESVKEMQRNWIGRSEGASVKFKVVGHDGV  242
            PV R PMRQW+LKITAYA+RL++DL+ VDWPES+K+MQRNWIG+S GA+V FKV + D  
Sbjct  183  PVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDK-  241

Query  243  EIEVFTTRADTLFGASYVVLAPENELVDQLTTPEQKAAVDAYKEEVSRRSDLERTELSKE  302
            ++ VFTTR+DTLFGA+Y VLAPE+ LVD +TT++Q  AV  YK + S +SDL RT+L+KE
Sbjct  242  DFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKE  301

Query  303  KTGVFTGAYVINPVNGEQLPIWTADYVLNSYGTGAVMAVPSGDQRDFEFATKFNLPITPV  362
            KTGV TG+Y INPVNG ++P+W ADYVL SYGTGA+MAVP+ D+RD EFA +FNL I PV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  363  VEGFNGEEA-YTEDGAHVNSGFLDGLNIKEAKAKMVEWLEEHDCGGKKVNYRLRDWIFSR  421
            +EG N EEA +TEDG H+NS+FLDGL+   A AKMVEWLE ++ G  +V YRLRDW+FSR
Sbjct  362  LEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSR  421

Query  422  QRYWGEPIPVIHWDDGTTSLVPEDELPLRLPETDNIEPSGTGESPLANIEDWVNVYDENG  481
            QRYWGEPIP+IHW+DGT++ VPE ELPL LP T +I PSGTGESPLAN+ DW++V  E+G
Sbjct  422  QRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDG  481

Query  482  RHGKRETNTMPQWAGSSWYWLRYTDPTNDKEFASKEALDYWSPVDLYVGGAEHAVLHLLY  541
              G+RETNTMPQWAGSSWY LRY DP N   +A  E L  W PVD+YVGGAEHAVLHLLY
Sbjct  482  VKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLY  541

Query  542  ARFWHKVLYDLGLVPTKEPFMKLVNQGMILGSN---------------------------  574
            ARFWHKVLYDLG+VPTKEPF KL NQGMILG++                           
Sbjct  542  ARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETG  601

Query  575  ------HEKMSKSKGNVVNPDDIVDQYGADTLRLYEMFMGPLEESVPWDEKGLHGSNKWV  628
                    KMSKS  NVVNPDD+V+QYGADTLR+YEMFMGPL+ S++W E GL+GS K +
Sbjct  602  EELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFL  661

Query  629  QRVWRLLMDDNNHLRDRVSTYNDGKLTKVYNQTVKKVTDDFERMHFNTAISQLMVFVNEA  688
            +RV RL+   +      ++  N G L KVYN+TVK VT++ ++M FNTAI+QLMVFVN A
Sbjct  662  DRVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAA  715

Query  689  YKVDDLPLEYMKGFVKMIAPLMPHLAEELWSQFNES-ETITYQPWPTYDEKALVEDEVEM  747
             K D L  +Y KGFV++IAP+ PHL+EELW  +  S E+I+Y PWP+YDE  LVE++VE+
Sbjct  716  NKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEI  775

Query  748  IVQVNGKVRAKIKMAKDADNKDVEDAALANEHVHS  782
            +VQ++GKV+AK+ +AKD    ++++ ALANE V++
Sbjct  776  VVQIKGKVKAKLVVAKDLSREELQEVALANEKVQA  810

394) Lp16_1014 in NC_021514


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  854 bits (3234),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 533/841 (64%), Positives = 663/841 (79%), Gaps = 46/841 (5%)

Query  3    YNHKVIERKWQHYWKENktfktldttdkkkYYALDMFPYPSGQGLHVGHPEGYTATDIMS  62
            Y+H  IE KWQ +W +N TFKT   + K K+YALDMFPYPSG GLHVGHPEGYTATDI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RFKRMQGYNVLHPMGWDAFGLPAEQYALKTGHNPKDFTAKNIKNFKRQIRSLGFSYDWDR  122
            RFKR QG NVLHPMGWDAFGLPAEQYA+ TG++P +FTA NI NFKRQI +LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVNTTDPSYYKWTQWIFEQLYKKGLAYESETLVNWAPDMMGGTVVSNEEVV-DGKTERGG  181
            EVNTTDP+YYKWTQWIF +LY KGLAYE+E  VNW  ++  GT ++NEEV+ DG +ERGG
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEEL--GTAIANEEVLPDGTSERGG  181

Query  182  YDVYRVPMKQWSLKITAYAdrliddlddidWPENIKEQQRNWIGRSVGASIRFKVAGQPD  241
            Y V R PM+QW LKITAYA+RL++DL+++DWPE+IK+ QRNWIG+S GA++ FKV  +  
Sbjct  182  YPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKV--KDT  239

Query  242  DTEIEVFSTRPDTLFGASYMVLAPEHDLVEQLTTPEQadaikaykakiasksdLERTDLN  301
            D ++ VF+TRPDTLFGA+Y VLAPEH LV+ +TT++QA+A+  YK + + KSDL RTDL 
Sbjct  240  DKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA  299

Query  302  KDKTGVFTGSYGINPVNGEKLPIWIADYVLASYGTGAIMAVPAHDDRDFEFAQKFDLPIK  361
            K+KTGV TGSY+INPVNG  +P+WIADYVLASYGTGAIMAVPAHD+RD EFA++F+L I 
Sbjct  300  KEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDII  359

Query  362  PVIAGDNDYDQQAYTGDGEHINSGFVDGLAKQPAIDKMIDWLGEHHTGEKKVNYRLRDWI  421
            PV+ G+N  ++ A+T DG HINS+F+DGL K +AI KM++WL  +  G+ +V YRLRDW+
Sbjct  360  PVLEGGNV-EEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWL  418

Query  422  FSRQRYWGEPIPVIHWEDGETTLVPEDELPLRLPATKNLEPSGTGESPLANIDDWVNVVD  481
            FSRQRYWGEPIP+IHWEDG +T VPE ELPL LP TK++ PSGTGESPLAN+ DW++V  
Sbjct  419  FSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTR  478

Query  482  ENGRKGKRETNTMPQWAGSSWYFLRYVDPHNREALADYDKLKYWSPVDLYVGGAEHAVLH  541
            E+G KG+RETNTMPQWAGSSWY+LRY+DPHN E LAD + LK W PVD+YVGGAEHAVLH
Sbjct  479  EDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLH  538

Query  542  LLYARFWHKFLYDLGVVPTKEPFQKLVNQGMILG--------------------------  575
            LLYARFWHK LYDLGVVPTKEPFQKL NQGMILG                          
Sbjct  539  LLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHV  598

Query  576  -------DNHEKMSKSRGNVVNPDDIVDQYGADTLRLYEMFMGPLEASIPWSTDGLHGAN  628
                   +   KMSKS  NVVNPDD+V+QYGADTLR+YEMFMGPL+ASI+WS +GL+G+ 
Sbjct  599  ETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSR  658

Query  629  KWIERVWRLMIDENNRVRDRITTINDGKLTKIYNETVKKVTEDYEAMRFNIAISQMMVFV  688
            K ++RV RL+   +      IT  N G L K+YNETVK VTE+ + M+FN AI+Q+MVFV
Sbjct  659  KFLDRVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFV  712

Query  689  NEAYKVDDLPIIYIEGFVKLLSPIAPHLSEELW-SLLGHDDTITYATWPTYDESKLVEDT  747
            N A K D L   Y  GFV+L++P+APHL+EELW +L + +++I+Y  WP+YDESKLVE+ 
Sbjct  713  NAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVEND  772

Query  748  VQIVLQVNGKVRSHAEVAKDMGKDELEKLALADEKIQEFTAGKTVRKVIAIPGKLVNVVA  807
            V+IV+Q++GKV++   VAKD++++EL+ +ALA+EK+Q   AGK + KVIA+P KLVN+V 
Sbjct  773  VEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

Query  808  N  808
            +
Sbjct  833  K  833

395) leuS in NC_012984


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  854 bits (3233),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 533/841 (64%), Positives = 663/841 (79%), Gaps = 46/841 (5%)

Query  3    YNHKVIERKWQHYWKENktfktldttdkkkYYALDMFPYPSGQGLHVGHPEGYTATDIMS  62
            Y+H  IE KWQ +W +N TFKT   + K K+YALDMFPYPSG GLHVGHPEGYTATDI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RFKRMQGYNVLHPMGWDAFGLPAEQYALKTGHNPKDFTAKNIKNFKRQIRSLGFSYDWDR  122
            RFKR QG NVLHPMGWDAFGLPAEQYA+ TG++P +FTA NI NFKRQI +LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVNTTDPSYYKWTQWIFEQLYKKGLAYESETLVNWAPDMMGGTVVSNEEVV-DGKTERGG  181
            EVNTTDP+YYKWTQWIF +LY KGLAYE+E  VNW  ++  GT ++NEEV+ DG +ERGG
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEEL--GTAIANEEVLPDGTSERGG  181

Query  182  YDVYRVPMKQWSLKITAYAdrliddlddidWPENIKEQQRNWIGRSVGASIRFKVAGQPD  241
            Y V R PM+QW LKITAYA+RL++DL+++DWPE+IK+ QRNWIG+S GA++ FKV  +  
Sbjct  182  YPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKV--KDT  239

Query  242  DTEIEVFSTRPDTLFGASYMVLAPEHDLVEQLTTPEQadaikaykakiasksdLERTDLN  301
            D ++ VF+TRPDTLFGA+Y VLAPEH LV+ +TT++QA+A+  YK + + KSDL RTDL 
Sbjct  240  DKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA  299

Query  302  KDKTGVFTGSYGINPVNGEKLPIWIADYVLASYGTGAIMAVPAHDDRDFEFAQKFDLPIK  361
            K+KTGV TGSY+INPVNG  +P+WIADYVLASYGTGAIMAVPAHD+RD EFA++F+L I 
Sbjct  300  KEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDII  359

Query  362  PVIAGDNDYDQQAYTGDGEHINSGFVDGLAKQPAIDKMIDWLGEHHAGEKKVNYRLRDWI  421
            PV+ G+N  ++ A+T DG HINS+F+DGL K +AI KM++WL  +  G+ +V YRLRDW+
Sbjct  360  PVLEGGNV-EEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWL  418

Query  422  FSRQRYWGEPIPVIHWEDGETTLVPEDELPLRLPATKNLEPSGTGESPLANIDDWVNVVD  481
            FSRQRYWGEPIP+IHWEDG +T VPE ELPL LP TK++ PSGTGESPLAN+ DW++V  
Sbjct  419  FSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTR  478

Query  482  ENGRKGKRETNTMPQWAGSSWYFLRYVDPHNREALADYDKLKYWSPVDLYVGGAEHAVLH  541
            E+G KG+RETNTMPQWAGSSWY+LRY+DPHN E LAD + LK W PVD+YVGGAEHAVLH
Sbjct  479  EDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLH  538

Query  542  LLYARFWHKFLYDLGVVPTKEPFQKLVNQGMILG--------------------------  575
            LLYARFWHK LYDLGVVPTKEPFQKL NQGMILG                          
Sbjct  539  LLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHV  598

Query  576  -------DNHEKMSKSRGNVVNPDDIVDQYGADTLRLYEMFMGPLEASIPWSTDGLHGAN  628
                   +   KMSKS  NVVNPDD+V+QYGADTLR+YEMFMGPL+ASI+WS +GL+G+ 
Sbjct  599  ETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSR  658

Query  629  KWIERVWRLMIDENNRVRDRITTINDGKLTKIYNETVKKVTEDYEAMRFNIAISQMMVFV  688
            K ++RV RL+   +      IT  N G L K+YNETVK VTE+ + M+FN AI+Q+MVFV
Sbjct  659  KFLDRVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFV  712

Query  689  NEAYKVDDLPIIYIEGFVKLLSPIAPHLSEELW-SLLGHDDTITYATWPTYDESKLVEDT  747
            N A K D L   Y  GFV+L++P+APHL+EELW +L + +++I+Y  WP+YDESKLVE+ 
Sbjct  713  NAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVEND  772

Query  748  VQIVLQVNGKVRSHAEVAKDMGKDELEKLALADEKIQEFTAGKTVRKVIAIPGKLVNVVA  807
            V+IV+Q++GKV++   VAKD++++EL+ +ALA+EK+Q   AGK + KVIA+P KLVN+V 
Sbjct  773  VEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

Query  808  N  808
            +
Sbjct  833  K  833

396) leuS in NC_021224


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  854 bits (3234),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 533/841 (64%), Positives = 663/841 (79%), Gaps = 46/841 (5%)

Query  3    YNHKVIERKWQHYWKENktfktldttdkkkYYALDMFPYPSGQGLHVGHPEGYTATDIMS  62
            Y+H  IE KWQ +W +N TFKT   + K K+YALDMFPYPSG GLHVGHPEGYTATDI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RFKRMQGYNVLHPMGWDAFGLPAEQYALKTGHNPKDFTAKNIKNFKRQIRSLGFSYDWDR  122
            RFKR QG NVLHPMGWDAFGLPAEQYA+ TG++P +FTA NI NFKRQI +LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVNTTDPSYYKWTQWIFEQLYKKGLAYESETLVNWAPDMMGGTVVSNEEVV-DGKTERGG  181
            EVNTTDP+YYKWTQWIF +LY KGLAYE+E  VNW  ++  GT ++NEEV+ DG +ERGG
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEEL--GTAIANEEVLPDGTSERGG  181

Query  182  YDVYRVPMKQWSLKITAYAdrliddlddidWPENIKEQQRNWIGRSVGASIRFKVAGQPD  241
            Y V R PM+QW LKITAYA+RL++DL+++DWPE+IK+ QRNWIG+S GA++ FKV  +  
Sbjct  182  YPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKV--KDT  239

Query  242  DTEIEVFSTRPDTLFGASYMVLAPEHDLVEQLTTPEQadaikaykakiasksdLERTDLN  301
            D ++ VF+TRPDTLFGA+Y VLAPEH LV+ +TT++QA+A+  YK + + KSDL RTDL 
Sbjct  240  DKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA  299

Query  302  KDKTGVFTGSYGINPVNGEKLPIWIADYVLASYGTGAIMAVPAHDDRDFEFAQKFDLPIK  361
            K+KTGV TGSY+INPVNG  +P+WIADYVLASYGTGAIMAVPAHD+RD EFA++F+L I 
Sbjct  300  KEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDII  359

Query  362  PVIAGDNDYDQQAYTGDGEHINSGFVDGLAKQPAIDKMIDWLGEHHTGEKKVNYRLRDWI  421
            PV+ G+N  ++ A+T DG HINS+F+DGL K +AI KM++WL  +  G+ +V YRLRDW+
Sbjct  360  PVLEGGNV-EEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWL  418

Query  422  FSRQRYWGEPIPVIHWEDGETTLVPEDELPLRLPATKNLEPSGTGESPLANIDDWVNVVD  481
            FSRQRYWGEPIP+IHWEDG +T VPE ELPL LP TK++ PSGTGESPLAN+ DW++V  
Sbjct  419  FSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTR  478

Query  482  ENGRKGKRETNTMPQWAGSSWYFLRYVDPHNREALADYDKLKYWSPVDLYVGGAEHAVLH  541
            E+G KG+RETNTMPQWAGSSWY+LRY+DPHN E LAD + LK W PVD+YVGGAEHAVLH
Sbjct  479  EDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLH  538

Query  542  LLYARFWHKFLYDLGVVPTKEPFQKLVNQGMILG--------------------------  575
            LLYARFWHK LYDLGVVPTKEPFQKL NQGMILG                          
Sbjct  539  LLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHV  598

Query  576  -------DNHEKMSKSRGNVVNPDDIVDQYGADTLRLYEMFMGPLEASIPWSTDGLHGAN  628
                   +   KMSKS  NVVNPDD+V+QYGADTLR+YEMFMGPL+ASI+WS +GL+G+ 
Sbjct  599  ETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSR  658

Query  629  KWIERVWRLMIDENNRVRDRITTINDGKLTKIYNETVKKVTEDYEAMRFNIAISQMMVFV  688
            K ++RV RL+   +      IT  N G L K+YNETVK VTE+ + M+FN AI+Q+MVFV
Sbjct  659  KFLDRVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFV  712

Query  689  NEAYKVDDLPIIYIEGFVKLLSPIAPHLSEELW-SLLGHDDTITYATWPTYDESKLVEDT  747
            N A K D L   Y  GFV+L++P+APHL+EELW +L + +++I+Y  WP+YDESKLVE+ 
Sbjct  713  NAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVEND  772

Query  748  VQIVLQVNGKVRSHAEVAKDMGKDELEKLALADEKIQEFTAGKTVRKVIAIPGKLVNVVA  807
            V+IV+Q++GKV++   VAKD++++EL+ +ALA+EK+Q   AGK + KVIA+P KLVN+V 
Sbjct  773  VEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

Query  808  N  808
            +
Sbjct  833  K  833

397) leuS in NC_014554


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  854 bits (3233),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 533/841 (64%), Positives = 663/841 (79%), Gaps = 46/841 (5%)

Query  3    YNHKVIERKWQHYWKENktfktldttdkkkYYALDMFPYPSGQGLHVGHPEGYTATDIMS  62
            Y+H  IE KWQ +W +N TFKT   + K K+YALDMFPYPSG GLHVGHPEGYTATDI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RFKRMQGYNVLHPMGWDAFGLPAEQYALKTGHNPKDFTAKNIKNFKRQIRSLGFSYDWDR  122
            RFKR QG NVLHPMGWDAFGLPAEQYA+ TG++P +FTA NI NFKRQI +LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVNTTDPSYYKWTQWIFEQLYKKGLAYESETLVNWAPDMMGGTVVSNEEVV-DGKTERGG  181
            EVNTTDP+YYKWTQWIF +LY KGLAYE+E  VNW  ++  GT ++NEEV+ DG +ERGG
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEEL--GTAIANEEVLPDGTSERGG  181

Query  182  YDVYRVPMKQWSLKITAYAdrliddlddidWPENIKEQQRNWIGRSVGASIRFKVAGQPD  241
            Y V R PM+QW LKITAYA+RL++DL+++DWPE+IK+ QRNWIG+S GA++ FKV  +  
Sbjct  182  YPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKV--KDT  239

Query  242  DTEIEVFSTRPDTLFGASYMVLAPEHDLVEQLTTPEQadaikaykakiasksdLERTDLN  301
            D ++ VF+TRPDTLFGA+Y VLAPEH LV+ +TT++QA+A+  YK + + KSDL RTDL 
Sbjct  240  DKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA  299

Query  302  KDKTGVFTGSYGINPVNGEKLPIWIADYVLASYGTGAIMAVPAHDDRDFEFAQKFDLPIK  361
            K+KTGV TGSY+INPVNG  +P+WIADYVLASYGTGAIMAVPAHD+RD EFA++F+L I 
Sbjct  300  KEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDII  359

Query  362  PVIAGDNDYDQQAYTGDGEHINSGFVDGLAKQPAIDKMIDWLGEHHAGEKKVNYRLRDWI  421
            PV+ G+N  ++ A+T DG HINS+F+DGL K +AI KM++WL  +  G+ +V YRLRDW+
Sbjct  360  PVLEGGNV-EEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWL  418

Query  422  FSRQRYWGEPIPVIHWEDGETTLVPEDELPLRLPATKNLEPSGTGESPLANIDDWVNVVD  481
            FSRQRYWGEPIP+IHWEDG +T VPE ELPL LP TK++ PSGTGESPLAN+ DW++V  
Sbjct  419  FSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTR  478

Query  482  ENGRKGKRETNTMPQWAGSSWYFLRYVDPHNREALADYDKLKYWSPVDLYVGGAEHAVLH  541
            E+G KG+RETNTMPQWAGSSWY+LRY+DPHN E LAD + LK W PVD+YVGGAEHAVLH
Sbjct  479  EDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLH  538

Query  542  LLYARFWHKFLYDLGVVPTKEPFQKLVNQGMILG--------------------------  575
            LLYARFWHK LYDLGVVPTKEPFQKL NQGMILG                          
Sbjct  539  LLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHV  598

Query  576  -------DNHEKMSKSRGNVVNPDDIVDQYGADTLRLYEMFMGPLEASIPWSTDGLHGAN  628
                   +   KMSKS  NVVNPDD+V+QYGADTLR+YEMFMGPL+ASI+WS +GL+G+ 
Sbjct  599  ETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSR  658

Query  629  KWIERVWRLMIDENNRVRDRITTINDGKLTKIYNETVKKVTEDYEAMRFNIAISQMMVFV  688
            K ++RV RL+   +      IT  N G L K+YNETVK VTE+ + M+FN AI+Q+MVFV
Sbjct  659  KFLDRVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFV  712

Query  689  NEAYKVDDLPIIYIEGFVKLLSPIAPHLSEELW-SLLGHDDTITYATWPTYDESKLVEDT  747
            N A K D L   Y  GFV+L++P+APHL+EELW +L + +++I+Y  WP+YDESKLVE+ 
Sbjct  713  NAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVEND  772

Query  748  VQIVLQVNGKVRSHAEVAKDMGKDELEKLALADEKIQEFTAGKTVRKVIAIPGKLVNVVA  807
            V+IV+Q++GKV++   VAKD++++EL+ +ALA+EK+Q   AGK + KVIA+P KLVN+V 
Sbjct  773  VEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

Query  808  N  808
            +
Sbjct  833  K  833

398) leuS in NC_004567


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  854 bits (3233),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 533/841 (64%), Positives = 663/841 (79%), Gaps = 46/841 (5%)

Query  3    YNHKVIERKWQHYWKENktfktldttdkkkYYALDMFPYPSGQGLHVGHPEGYTATDIMS  62
            Y+H  IE KWQ +W +N TFKT   + K K+YALDMFPYPSG GLHVGHPEGYTATDI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RFKRMQGYNVLHPMGWDAFGLPAEQYALKTGHNPKDFTAKNIKNFKRQIRSLGFSYDWDR  122
            RFKR QG NVLHPMGWDAFGLPAEQYA+ TG++P +FTA NI NFKRQI +LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVNTTDPSYYKWTQWIFEQLYKKGLAYESETLVNWAPDMMGGTVVSNEEVV-DGKTERGG  181
            EVNTTDP+YYKWTQWIF +LY KGLAYE+E  VNW  ++  GT ++NEEV+ DG +ERGG
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEEL--GTAIANEEVLPDGTSERGG  181

Query  182  YDVYRVPMKQWSLKITAYAdrliddlddidWPENIKEQQRNWIGRSVGASIRFKVAGQPD  241
            Y V R PM+QW LKITAYA+RL++DL+++DWPE+IK+ QRNWIG+S GA++ FKV  +  
Sbjct  182  YPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKV--KDT  239

Query  242  DTEIEVFSTRPDTLFGASYMVLAPEHDLVEQLTTPEQadaikaykakiasksdLERTDLN  301
            D ++ VF+TRPDTLFGA+Y VLAPEH LV+ +TT++QA+A+  YK + + KSDL RTDL 
Sbjct  240  DKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA  299

Query  302  KDKTGVFTGSYGINPVNGEKLPIWIADYVLASYGTGAIMAVPAHDDRDFEFAQKFDLPIK  361
            K+KTGV TGSY+INPVNG  +P+WIADYVLASYGTGAIMAVPAHD+RD EFA++F+L I 
Sbjct  300  KEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDII  359

Query  362  PVIAGDNDYDQQAYTGDGEHINSGFVDGLAKQPAIDKMIDWLGEHHAGEKKVNYRLRDWI  421
            PV+ G+N  ++ A+T DG HINS+F+DGL K +AI KM++WL  +  G+ +V YRLRDW+
Sbjct  360  PVLEGGNV-EEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWL  418

Query  422  FSRQRYWGEPIPVIHWEDGETTLVPEDELPLRLPATKNLEPSGTGESPLANIDDWVNVVD  481
            FSRQRYWGEPIP+IHWEDG +T VPE ELPL LP TK++ PSGTGESPLAN+ DW++V  
Sbjct  419  FSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTR  478

Query  482  ENGRKGKRETNTMPQWAGSSWYFLRYVDPHNREALADYDKLKYWSPVDLYVGGAEHAVLH  541
            E+G KG+RETNTMPQWAGSSWY+LRY+DPHN E LAD + LK W PVD+YVGGAEHAVLH
Sbjct  479  EDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLH  538

Query  542  LLYARFWHKFLYDLGVVPTKEPFQKLVNQGMILG--------------------------  575
            LLYARFWHK LYDLGVVPTKEPFQKL NQGMILG                          
Sbjct  539  LLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHV  598

Query  576  -------DNHEKMSKSRGNVVNPDDIVDQYGADTLRLYEMFMGPLEASIPWSTDGLHGAN  628
                   +   KMSKS  NVVNPDD+V+QYGADTLR+YEMFMGPL+ASI+WS +GL+G+ 
Sbjct  599  ETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSR  658

Query  629  KWIERVWRLMIDENNRVRDRITTINDGKLTKIYNETVKKVTEDYEAMRFNIAISQMMVFV  688
            K ++RV RL+   +      IT  N G L K+YNETVK VTE+ + M+FN AI+Q+MVFV
Sbjct  659  KFLDRVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFV  712

Query  689  NEAYKVDDLPIIYIEGFVKLLSPIAPHLSEELW-SLLGHDDTITYATWPTYDESKLVEDT  747
            N A K D L   Y  GFV+L++P+APHL+EELW +L + +++I+Y  WP+YDESKLVE+ 
Sbjct  713  NAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVEND  772

Query  748  VQIVLQVNGKVRSHAEVAKDMGKDELEKLALADEKIQEFTAGKTVRKVIAIPGKLVNVVA  807
            V+IV+Q++GKV++   VAKD++++EL+ +ALA+EK+Q   AGK + KVIA+P KLVN+V 
Sbjct  773  VEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

Query  808  N  808
            +
Sbjct  833  K  833

399) leuS in NC_020229


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  854 bits (3233),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 533/841 (64%), Positives = 663/841 (79%), Gaps = 46/841 (5%)

Query  3    YNHKVIERKWQHYWKENktfktldttdkkkYYALDMFPYPSGQGLHVGHPEGYTATDIMS  62
            Y+H  IE KWQ +W +N TFKT   + K K+YALDMFPYPSG GLHVGHPEGYTATDI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RFKRMQGYNVLHPMGWDAFGLPAEQYALKTGHNPKDFTAKNIKNFKRQIRSLGFSYDWDR  122
            RFKR QG NVLHPMGWDAFGLPAEQYA+ TG++P +FTA NI NFKRQI +LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVNTTDPSYYKWTQWIFEQLYKKGLAYESETLVNWAPDMMGGTVVSNEEVV-DGKTERGG  181
            EVNTTDP+YYKWTQWIF +LY KGLAYE+E  VNW  ++  GT ++NEEV+ DG +ERGG
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEEL--GTAIANEEVLPDGTSERGG  181

Query  182  YDVYRVPMKQWSLKITAYAdrliddlddidWPENIKEQQRNWIGRSVGASIRFKVAGQPD  241
            Y V R PM+QW LKITAYA+RL++DL+++DWPE+IK+ QRNWIG+S GA++ FKV  +  
Sbjct  182  YPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKV--KDT  239

Query  242  DTEIEVFSTRPDTLFGASYMVLAPEHDLVEQLTTPEQadaikaykakiasksdLERTDLN  301
            D ++ VF+TRPDTLFGA+Y VLAPEH LV+ +TT++QA+A+  YK + + KSDL RTDL 
Sbjct  240  DKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA  299

Query  302  KDKTGVFTGSYGINPVNGEKLPIWIADYVLASYGTGAIMAVPAHDDRDFEFAQKFDLPIK  361
            K+KTGV TGSY+INPVNG  +P+WIADYVLASYGTGAIMAVPAHD+RD EFA++F+L I 
Sbjct  300  KEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDII  359

Query  362  PVIAGDNDYDQQAYTGDGEHINSGFVDGLAKQPAIDKMIDWLGEHHAGEKKVNYRLRDWI  421
            PV+ G+N  ++ A+T DG HINS+F+DGL K +AI KM++WL  +  G+ +V YRLRDW+
Sbjct  360  PVLEGGNV-EEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWL  418

Query  422  FSRQRYWGEPIPVIHWEDGETTLVPEDELPLRLPATKNLEPSGTGESPLANIDDWVNVVD  481
            FSRQRYWGEPIP+IHWEDG +T VPE ELPL LP TK++ PSGTGESPLAN+ DW++V  
Sbjct  419  FSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTR  478

Query  482  ENGRKGKRETNTMPQWAGSSWYFLRYVDPHNREALADYDKLKYWSPVDLYVGGAEHAVLH  541
            E+G KG+RETNTMPQWAGSSWY+LRY+DPHN E LAD + LK W PVD+YVGGAEHAVLH
Sbjct  479  EDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLH  538

Query  542  LLYARFWHKFLYDLGVVPTKEPFQKLVNQGMILG--------------------------  575
            LLYARFWHK LYDLGVVPTKEPFQKL NQGMILG                          
Sbjct  539  LLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHV  598

Query  576  -------DNHEKMSKSRGNVVNPDDIVDQYGADTLRLYEMFMGPLEASIPWSTDGLHGAN  628
                   +   KMSKS  NVVNPDD+V+QYGADTLR+YEMFMGPL+ASI+WS +GL+G+ 
Sbjct  599  ETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSR  658

Query  629  KWIERVWRLMIDENNRVRDRITTINDGKLTKIYNETVKKVTEDYEAMRFNIAISQMMVFV  688
            K ++RV RL+   +      IT  N G L K+YNETVK VTE+ + M+FN AI+Q+MVFV
Sbjct  659  KFLDRVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFV  712

Query  689  NEAYKVDDLPIIYIEGFVKLLSPIAPHLSEELW-SLLGHDDTITYATWPTYDESKLVEDT  747
            N A K D L   Y  GFV+L++P+APHL+EELW +L + +++I+Y  WP+YDESKLVE+ 
Sbjct  713  NAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVEND  772

Query  748  VQIVLQVNGKVRSHAEVAKDMGKDELEKLALADEKIQEFTAGKTVRKVIAIPGKLVNVVA  807
            V+IV+Q++GKV++   VAKD++++EL+ +ALA+EK+Q   AGK + KVIA+P KLVN+V 
Sbjct  773  VEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

Query  808  N  808
            +
Sbjct  833  K  833

400) LC40_0860 in NC_017465


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  854 bits (3235),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 508/815 (63%), Positives = 634/815 (78%), Gaps = 43/815 (5%)

Query  3    YDHKAIEKKWQRYWKQHKTFKATLDKDQKKYYALDMFPYPSGQGLHVGHPEGYTATDVMS  62
            YDH AIE KWQ +W ++ TFK+  D  + K+YALDMFPYPSG GLHVGHPEGYTATD++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RLKRMQGFNVLHPMGWDAFGLPAEQYALKTGHNPADFTNQNVDHFRDQIQSLGFSYDWDR  122
            R+KR QG NVLHPMGWDAFGLPAEQYA+ TG++PA+FT +N+ +F+ QI++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVNTTDPNYYKWTQWIFEQLYKKGLAYEDEIMVNWAPDFMGGTVVANEEVVDGKTERGGY  182
            EVNTTDPNYYKWTQWIF +LY KGLAYE E+ VNW  + +G ++  +E + DG +ERGGY
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEE-LGTAIANEEVLPDGTSERGGY  182

Query  183  PVYRVPMRQWVLKITAYADRLIDDLDLVDWPESVKEMQRNWIGRSEGASVKFKVVGHDGV  242
            PV R PMRQW+LKITAYA+RL++DL+ VDWPES+K+MQRNWIG+S GA+V FKV + D  
Sbjct  183  PVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDK-  241

Query  243  EIEVFTTRADTLFGASYVVLAPENELVDQLTTPEQKAAVDAYKEEASRRSDLERTELSKE  302
            ++ VFTTR+DTLFGA+Y VLAPE+ LVD +TT++Q  AV  YK +AS +SDL RT+L+KE
Sbjct  242  DFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKE  301

Query  303  KTGVFTGAYVINPVNGEQLPIWTADYVLNSYGTGAVMAVPSGDQRDFEFATKFNLPITPV  362
            KTGV TG+Y INPVNG ++P+W ADYVL SYGTGA+MAVP+ D+RD EFA +FNL I PV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  363  VEGFNGEEA-YTEDGAHVNSGFLDGLNIKEAKAKMVEWLEEHDCGGKKVNYRLRDWIFSR  421
            +EG N EEA +TEDG H+NS+FLDGL+   A AKMVEWLE ++ G  +V YRLRDW+FSR
Sbjct  362  LEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSR  421

Query  422  QRYWGEPIPVIHWDDGTTSLVPEDELPLRLPETDNIEPSGTGESPLANIEDWVNVYDENG  481
            QRYWGEPIP+IHW+DGT++ VPE ELPL LP T +I PSGTGESPLAN+ DW++V  E+G
Sbjct  422  QRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDG  481

Query  482  RHGKRETNTMPQWAGSSWYWLRYTDPTNDKEFASKEALDYWSPVDLYVGGAEHAVLHLLY  541
              G+RETNTMPQWAGSSWY LRY DP N   +A  E L  W PVD+YVGGAEHAVLHLLY
Sbjct  482  VKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLY  541

Query  542  ARFWHKVLYDLGLVPTKEPFMKLVNQGMILGSN---------------------------  574
            ARFWHKVLYDLG+VPTKEPF KL NQGMILG++                           
Sbjct  542  ARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETG  601

Query  575  ------HEKMSKSKGNVVNPDDIVDQYGADTLRLYEMFMGPLEESVPWDEKGLHGSNKWV  628
                    KMSKS  NVVNPDD+V+QYGADTLR+YEMFMGPL+ S++W E GL+GS K +
Sbjct  602  EELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFL  661

Query  629  QRVWRLLMDDNNHLRDRVSTYNDGKLTKVYNQTVKKVTDDFERMHFNTAISQLMVFVNEA  688
            +RV RL+   +      ++  N G L KVYN+TVK VT++ ++M FNTAI+QLMVFVN A
Sbjct  662  DRVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAA  715

Query  689  YKVDNLPLEYMEGFVKMIAPLMPHLAEELWSQFNES-ETITYQPWPTYDEKALVEDEVEM  747
             K D+L  +Y  GFV++IAP+ PHL+EELW  +  S E+I+Y PWP+YDE  LVE++VE+
Sbjct  716  NKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEI  775

Query  748  IVQVNGKVRAKIKMAKDADNKDVEDAALANEHVHS  782
            +VQ++GKV+AK+ +AKD    ++++ ALANE V++
Sbjct  776  VVQIKGKVKAKLVVAKDLSREELQEVALANEKVQA  810

401) leuS in NC_021235


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  854 bits (3233),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 508/815 (63%), Positives = 634/815 (78%), Gaps = 43/815 (5%)

Query  3    YDHKAIEKKWQRYWKQHKTFKATLDKDQKKYYALDMFPYPSGQGLHVGHPEGYTATDVMS  62
            YDH AIE KWQ +W ++ TFK+  D  + K+YALDMFPYPSG GLHVGHPEGYTATD++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RLKRMQGFNVLHPMGWDAFGLPAEQYALKTGHNPADFTNQNVDHFRDQIQSLGFSYDWDR  122
            R+KR QG NVLHPMGWDAFGLPAEQYA+ TG++PA+FT +N+ +F+ QI++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVNTTDPNYYKWTQWIFEQLYKKGLAYEDEIMVNWAPDFMGGTVVANEEVVDGKTERGGY  182
            EVNTTDPNYYKWTQWIF +LY KGLAYE E+ VNW  + +G ++  +E + DG +ERGGY
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEE-LGTAIANEEVLPDGTSERGGY  182

Query  183  PVYRVPMRQWVLKITAYADRLIDDLDLVDWPESVKEMQRNWIGRSEGASVKFKVVGHDGV  242
            PV R PMRQW+LKITAYA+RL++DL+ VDWPES+K+MQRNWIG+S GA+V FKV + D  
Sbjct  183  PVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDK-  241

Query  243  EIEVFTTRADTLFGASYVVLAPENELVDQLTTPEQKAAVDAYKEEASRRSDLERTELSKE  302
            ++ VFTTR+DTLFGA+Y VLAPE+ LVD +TT++Q  AV  YK +AS +SDL RT+L+KE
Sbjct  242  DFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKE  301

Query  303  KTGVFTGSYVINPVNGEQLPIWTADYVLNSYGTGAVMAVPSGDQRDFEFATKFNLPITPV  362
            KTGV TGSY INPVNG ++P+W ADYVL SYGTGA+MAVP+ D+RD EFA +FNL I PV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  363  VEGFNGEEA-YTEDGAHVNSGFLDGLNIKEAKAKMVEWLEEHDCGGKKVNYRLRDWIFSR  421
            +EG N EEA +TEDG H+NS+FLDGL+   A AKMVEWLE ++ G  +V YRLRDW+FSR
Sbjct  362  LEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSR  421

Query  422  QRYWGEPIPVIHWDDGTTSLVPEDELPLRLPETDNIEPSGTGESPLANIEDWVNVYDENG  481
            QRYWGEPIP+IHW+DGT++ VPE ELPL LP T +I PSGTGESPLAN+ DW++V  E+G
Sbjct  422  QRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDG  481

Query  482  RHGKRETNTMPQWAGSSWYWLRYTDPTNDKEFASKEALDYWSPVDLYVGGAEHAVLHLLY  541
              G+RETNTMPQWAGSSWY LRY DP N   +A  E L  W PVD+YVGGAEHAVLHLLY
Sbjct  482  VKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLY  541

Query  542  ARFWHKVLYDLGLVPTKEPFMKLVNQGMILGSN---------------------------  574
            ARFWHKVLYDLG+VPTKEPF KL NQGMILG++                           
Sbjct  542  ARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETG  601

Query  575  ------HEKMSKSKGNVVNPDDIVDQYGADTLRLYEMFMGPLEESVPWDEKGLHGANKWV  628
                    KMSKS  NVVNPDD+V+QYGADTLR+YEMFMGPL+ S++W E GL+G+ K +
Sbjct  602  EELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFL  661

Query  629  QRVWRLLMDDNNHLRDRVSTYNDGKLTKVYNQTVKKVTDDFERMHFNTAISQLMVFVNEA  688
            +RV RL+   +      ++  N G L KVYN+TVK VT++ ++M FNTAI+QLMVFVN A
Sbjct  662  DRVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAA  715

Query  689  YKVDVLPVEYMEGFVKMIAPLMPHLAEELWSQFNES-ETITYQPWPTYDEKALVEDEVEM  747
             K D L  +Y  GFV++IAP+ PHL+EELW  +  S E+I+Y PWP+YDE  LVE++VE+
Sbjct  716  NKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEI  775

Query  748  IVQVNGKVRAKIKMAKDADKRDVEDAALANEHVHS  782
            +VQ++GKV+AK+ +AKD  + ++++ ALANE V++
Sbjct  776  VVQIKGKVKAKLVVAKDLSREELQEVALANEKVQA  810

402) leuS in NC_013406


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  851 bits (3223),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 533/836 (64%), Positives = 660/836 (79%), Gaps = 43/836 (5%)

Query  11   YQPQAIEPKWQQYWDENKTFKTEETSSKPKFYALDMFPYPSGAGLHVGHPEGYTATDIVS  70
            Y+  AIEPKWQ +W +N TFKT   +SKPKFYALDMFPYPSGAGLHVGHPEGYTATDI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  71   RYKRMRGYNVLHPMGWDAFGLPAEQYAMDTGKHPREFTVQNIDTFRRQIKSLGFSYDWDR  130
            R+KR +G NVLHPMGWDAFGLPAEQYAMDTG++P EFT +NI  F+RQI++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  131  EISTTDPEYYKWTQWIFIQLYKRGLAYVAEVPVNWCEALGTVLANEEVI-DGKSERGGHP  189
            E++TTDP+YYKWTQWIF +LY +GLAY AEVPVNW E LGT +ANEEV+ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  190  VVRKPMRQWILRITEYAdrlledldeldwseslkdMQRNWIGKSTGAEVRFDIEGYDGHL  249
            VVRKPMRQW+L+IT YA+RLLEDL+E+DW+ES+KDMQRNWIGKSTGA+V F + + D ++
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  250  EVFTTRPDTLFGASYCVLAPEHDLVDKIATADQREAVKAYQDQAARKSDLERTDLAKDKT  309
             VFTTRPDTLFGA+Y VLAPEH LVD I+T+DQ EAV  Y+ QA+ KSDL RTDLAK+KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  310  GVFTGAYAVNPVNGAKVPIWIADYVLAGYGTGAIMAVPGHDSRDWEFAKQFGLPIIEVVQ  369
            GV TG+YA+NPVNG  +P+WIADYVLA+YGTGAIMAVP+HD RDWEFAKQF L II V++
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  370  GGNVEEEAYTGTGAHVNSGFLNGLDNEAAIQAMNEWLekegkgkkkVTYRLRDWLFSRQR  429
            GGNVEE A+T  G H+NS+FL+GLD+ +AI  M EWLE EG G+ +VTYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  430  YWGEPIPILHLEDGTMKTvpedqlplllpdvdqIKPSGTGESPLANVTEWVETVDPETGM  489
            YWGEPIPI+H EDGT  +VPE +LPL+LP   +I+PSGTGESPLANVT+W+E V  E G+
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE-VTREDGV  482

Query  490  KARRETNTMPQWAGSCWYYLRYIDPDNHDELCSKEKQKEWLPVDLYIGGVEHAVLHLLYA  549
            K+RRETNTMPQWAGS WYYLRYIDP+N + L   E  K+WLPVD+Y+GG EHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  550  RFWHKVLYDLGVVDTKEPFQKLVNQGMILGNN----------------------------  581
            RFWHKVLYDLGVV TKEPFQKL NQGMILG +                            
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  582  -----NEKMSKSRGNVINPDDIVNEYGADTLRVYEMFMGPLEATKPWNTNGVEGTHRFLS  636
                   KMSKS  NV+NPDD+V++YGADTLRVYEMFMGPL+A+ +W+ +G+EG+++FL 
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  637  RVWRLFIGDDGQLNPKIVDGEGTDEFKRTLHKTIKKVTDDFEHLRFNTAISQLMIFINEG  696
            RV RL       +  K +  E ++ + +  + T+K VT++ ++++FNTAI+QLM+F+N +
Sbjct  663  RVYRL-------ITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAA  715

Query  697  YKSEVLPRKAMENFVQLLSPLAPHLAEELWSRL-GYTESVTYVPWPEFDEAWTVEAEVEI  755
             K + L       FVQL++P+APHL+EELW  L +  ES++YVPWP +DE+  VE +VEI
Sbjct  716  NKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEI  775

Query  756  VVQVNGKIVERAKIAKDMDQEAMQQHSLSLPNVKQALEGKSIRKIIAVPGKLVNIV  811
            VVQ++GK+  +  +AKD+ +E +Q+ +L+  +V+  + GK I K+IAVP KLVNIV
Sbjct  776  VVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIV  831

403) leuS in NC_018665


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  850 bits (3218),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 523/834 (63%), Positives = 662/834 (80%), Gaps = 39/834 (4%)

Query  3    YNHRDIEPKWQARWEQDNAFVTTEDPEKEGFYALDMFPYPSGAGLHVGHPEGYTATDILA  62
            Y+H  IEPKWQA W ++++F T  D+ K  FYALDMFPYPSGAGLHVGHPEGYTATDIL+
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMKRMQGYNVLHPMGWDAFGLPAEQYALDTGNDPREFTAQNIETFKRQLKDLGFSYDWDR  122
            R KR QG NVLHPMGWDAFGLPAEQYA+DTGNDP EFTA+NI  FKRQ++ LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EINTTDPKYYKWTQWIFTQLYEKGLAFVDEVAVNWCPALGTVLANEEVI-DGLSERGNHP  181
            E+NTTDP+YYKWTQWIFT+LYEKGLA+  EV+VNW   LGT +ANEEV+ DG SERG  P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VVRVPMRQWVLKITDYAdrlledldeldWPESVKEMQRNWIGKSEGAEIDFTIDGHKKQV  241
            VVR PMRQW+LKIT YA+RLLEDL+E+DWPES+K+MQRNWIGKS GA++ F + +  K+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  TVFTTRPDTVFGATYLVLAPEHPFVSDITTADHTEAVQSYIASVQTKSDLERTDLAKEKT  301
            TVFTTRPDT+FGATY VLAPEH++V  ITT+D++EAV  Y      KSDL RTDLAKEKT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAFAVNPISGERLPIWIADYVLSTYGTGAIMAVPAHDERDHEFAKQFDLPIIEVVQ  361
            GV TG++A+NP++G  +P+WIADYVL++YGTGAIMAVPAHDERD EFAKQF+L II V++
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  GGKVEEAAYTGEGAHVNSQMLDGLSKDeaietiiaeletNQVGRKKITFRLRDWLFSRQR  421
            GG+VEEAA+T +G H+NS+ LDGL K  AI  ++  LE++ VG  ++T+RLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  422  YWGEPIPVVHMEDGTMKTLDKSelplelpiipeiKPSGTGESPLALAEDWLDYTDPVTGQ  481
            YWGEPIP++H EDGT  ++  SELPL LP+  +I+PSGTGESPLA   DWL+      G 
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE-VTREDGV  482

Query  482  KGRRETNTMPQWGGSCWYYLRFIDPHNEEMFADPEKLKYWLPVDIYIGGAEHAVLHLLYA  541
            KGRRETNTMPQW+GS WYYLR+IDPHN E +AD E LK WLPVDIY+GGAEHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  542  RFWHKVLYDIGVVPTKEPFQKLYNQGMILG------------------------------  571
            RFWHKVLYD+GVVPTKEPFQKL+NQGMILG                              
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  572  ---ENNEKMSKSRGNVINPDEIVKSHGADTLRLYEMFMGPLDASVSWSENGLDGARRFLD  628
               +   KMSKS  NV+NPD++V   GADTLR+YEMFMGPLDAS++WSE+GL+G+R+FLD
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  629  RVWRLFERTADIQDVTSVDADFERVYHQTVKKVTEDFTNIQFNTGISQLMVFVNEANKQP  688
            RV RL+      ++ +   + +++VY++TVK VTE+  +++FNT+I+QLMVFVN ANK+ 
Sbjct  663  RVYRLITTKEITEENS---GALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKED  719

Query  689  VLPRHFLRGFIQLLTPVAPHLGEELWEQL-GFEETLTYASWPTFDETKLVSDTMEFVIQV  747
             L  ++ +GF+QL++P APHLGEELW+ L +  E+++Y +WP++DE+KLV + +E+V+Q+
Sbjct  720  KLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQI  779

Query  748  NGKVRSKLVISTEATKEEIEALAFADEKTQEWIGEKTVRKVIVVPKKLINIVAN  801
            +GKV++KLV++ + ++EE++ +A+A+EK Q  I+ K + KVI VP+KL+NIV +
Sbjct  780  KGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

404) leuS in NC_018610


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  846 bits (3202),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 502/820 (62%), Positives = 630/820 (77%), Gaps = 42/820 (5%)

Query  3    YNHEVIERKWQHYWKEHKTFKTEEVADKDKYYVLDMFPYPSGQGLHVGHPEGYTATDIMA  62
            Y+H  IE KWQ +W ++ TFKT   A K K+Y LDMFPYPSG GLHVGHPEGYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMKRMQGKNVLHPMGWDAFGLPAEQYALKTGHNPRDFTAKNIKTFKRQIRSLGFSYDWDR  122
            R KR QG NVLHPMGWDAFGLPAEQYA+ TG++P +FTA NI  FKRQI +LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EINTTDPSYYKWTQWIFEELYKRGLAYEDNIEVNWAPDFMGGTVVANEEVVDGKTERGGY  182
            E+NTTDP+YYKWTQWIF  LY +GLAYE ++ VNW  + +G ++  +E + DG +ERGGY
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEE-LGTAIANEEVLPDGTSERGGY  182

Query  183  PVYRVPMRQWVLKITAYAdrliddlddldWPESIKEQQRNWIGRSRGASVFFEVKGHPDD  242
            PV R PMRQW+LKITAYA+RL++DL+++DWPESIK+ QRNWIG+S GA+V F VK + D 
Sbjct  183  PVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVK-DTDK  241

Query  243  KVEVFTTRPDTLFGATYMVLAPEHQLVSKITTPEQAAEVKAYQEEVSRKSDLERTDLNKD  302
               VFTTRPDTLFGATY VLAPEH LV  ITT++QA  V  Y+ + S KSDL RTDL K+
Sbjct  242  DFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKE  301

Query  303  KSGVFTGAYGINPMTGKEVPIWIGDYVLESYGTGAIMAVPAHDDRDYDFAKKFGLPIVPV  362
            K+GV TG+Y+INP+ GKE+P+WI+DYVL SYGTGAIMAVPAHD+RD +FAK+F L I+PV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  363  IEGGNTDEAAYTGDGPHFNSGFMDGMGKDDAIKAAIDWLTDHKAGHEKVNYRLRDWIFSR  422
            +EGGN +EAA+T DG H+NS+F+DG++K  AI   ++WL  +  G+E+V YRLRDW+FSR
Sbjct  362  LEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSR  421

Query  423  QRYWGEPIPVIHWEDGETTLVPEDELPLRLPKAKDIQTSGGKESPLANLDDWVNVVDKNG  482
            QRYWGEPIP+IHWEDG +T VPE ELPL LP +KDI+ SG  ESPLAN+ DW++V   +G
Sbjct  422  QRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDG  481

Query  483  RKGKRETNTMPQWAGSSWYWLRYMDPHNDQAIASPEKLKYWSPVDLYVGGAEHAVLHLLY  542
             KG+RETNTMPQWAGSSWY LRY+DPHN + +A  E LK W PVD+YVGGAEHAVLHLLY
Sbjct  482  VKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLY  541

Query  543  ARFWHKFLYDLGVVPTKEPFQKLVNQGMILGTN---------------------------  575
            ARFWHK LYDLGVVPTKEPFQKL NQGMILGT+                           
Sbjct  542  ARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETG  601

Query  576  ------HEKMSKSKGNVINPDDIVDEYGADTLRVYEMFMGPIDAAKPWSTEGIHGAYHWL  629
                    KMSKS  NV+NPDD+V++YGADTLRVYEMFMGP+DA+ +WS EG++G+   L
Sbjct  602  EELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFL  661

Query  630  DRVWRLLIDDNNHLRDRVTTINDGKLDKIYNQTVKIVSDDFEHMRFNVGISQMMVFVNDA  689
            DRV RL+   +      +T  N G LDK+YN+TVK V+++ ++M+FN +I+Q+MVFVN A
Sbjct  662  DRVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAA  715

Query  690  YKADSLPIDYMEGFVKLLSPVAPHIAEELWSLLGHDG-TITYEKWPTYDASKLVENTVQM  748
             K D L  DY  GFV+L++P APH++EELW  L   G +I+Y  WP+YD SKLVEN V++
Sbjct  716  NKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEI  775

Query  749  VVQVNGKVRSHIKVARDLDKEKVEQTAKSDENVERYLEGK  788
            VVQ++GKV++ + VA+DL +E +++ A ++E+V+  + GK
Sbjct  776  VVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGK  815

405) leuS in NC_008497


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  845 bits (3199),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 522/842 (62%), Positives = 659/842 (79%), Gaps = 47/842 (5%)

Query  3    YKHQIIERKWQHYWRANHTFETSDSQTKPKYYVMDMFPYPSGQGLHVGHPEGYTATDIMA  62
            Y H  IE KWQ +W  NHTF T+   +KPK+Y +DMFPYPSG GLHVGHPEGYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RLKRMQGFNVLHPMGWDAFGLPAEQYALKTGHNPKDFTAHNIKNFKRQIRSLGFSYDWSR  122
            R+KR QG NVLHPMGWDAFGLPAEQYA+ TG++P +FTA+NI NFKRQI +LGFSYDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EINTTDESYYKWTQWIFEQLYKKGLAYEDKIMVNWAPDFMGGTVVANEEVI-DGKTERGG  181
            E+NTTD +YYKWTQWIF +LY KGLAYE  + VNW  ++  GT +ANEEV+ DG +ERGG
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEEL--GTAIANEEVLPDGTSERGG  181

Query  182  YPVYRVPMRQWVLKITAYAdrliddlddldwpdSIKEMQRNWIGRSEGASVFFPVDGQAD  241
            YPV R PMRQW+LKITAYA+RL++DL+++DWP+SIK+MQRNWIG+S GA+V F V  ++D
Sbjct  182  YPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVK-DTD  240

Query  242  TKIEVYTTRPDTLFGATYMVLAPEHAAVAKITTPEQADAVKAYQEAIESKSDLERTDLNK  301
              + V+TTRPDTLFGATY VLAPEHA V  ITT++QA+AV  Y+     KSDL RTDL K
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  302  DKTGVFTGAYGINPLSGKKLPIWIGDYVLSSYGTGAIMAVPAHDERDHEFATKFNLPITQ  361
            +KTGV TG+Y+INP++GK +P+WI+DYVL+SYGTGAIMAVPAHDERD EFA +FNL I  
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  362  VIEGDADTDITEAAYTDDGKHINSDFMNGMDKQTAISAAIDWLTEHDAGHKQVNFRLRDW  421
            V+EG+   ++ EAA+T+DG HINSDF++G+DK +AI+  ++WL  ++ G+ +V +RLRDW
Sbjct  361  VLEGG---NVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDW  417

Query  422  IFSRQRYWGEPIPVIHWENGETTLVPEDELPLKLPAAKQLEPSGTGESPLANLDDWVNVV  481
            +FSRQRYWGEPIP+IHWE+G +T VPE ELPL LP +K++ PSGTGESPLAN+ DW++V 
Sbjct  418  LFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT  477

Query  482  DENGRKGKRETNTMPQWAGSSWYFLRYVDPTNDQAIADPEKLKYWMPVDLYIGGAEHAVL  541
             E+G KG+RETNTMPQWAGSSWY+LRY+DP N + +AD E LK W+PVD+Y+GGAEHAVL
Sbjct  478  REDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVL  537

Query  542  HLLYARFWHKFLYDLGVVPTKEPFQKLVNQGMILGTN-----------------------  578
            HLLYARFWHK LYDLGVVPTKEPFQKL NQGMILGT+                       
Sbjct  538  HLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFH  597

Query  579  ----------HEKMSKSKGNVINPDEIVEKHGADTLRLYEMFMGPLEASKPWSTEGINGS  628
                        KMSKS  NV+NPD++VE+ GADTLR+YEMFMGPL+AS +WS EG++GS
Sbjct  598  VETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGS  657

Query  629  RRWLDRVWRLLIDDNNRLRDRVTMINDGALDKIYNQTVKTVTEDLEAMRFNVAISQLMVF  688
            R+ LDRV RL+   +      +T  N GALDK+YN+TVK+VTE+++ M+FN AI+QLMVF
Sbjct  658  RKFLDRVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVF  711

Query  689  VNEAYKVDSLPMIYMEGFVKLISPIVPHIAEELW-SLLGHDETIAYAKWPTYDAKqlved  747
            VN A K D L   Y  GFV+LI+P+ PH++EELW +L + +E+I+Y  WP+YD  +LVE+
Sbjct  712  VNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVEN  771

Query  748  vvelvvqvNGKVRAHLKVAKDATKDAIEAAALADETVQVHTDGKTVRKVIVVPGKLVNIV  807
             VE+VVQ++GKV+A L VAKD +++ ++  ALA+E VQ +  GK + KVI VP KLVNIV
Sbjct  772  DVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIV  831

Query  808  AN  809
             +
Sbjct  832  IK  833

406) Lbuc_1271 in NC_015428


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  845 bits (3200),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 500/820 (61%), Positives = 630/820 (77%), Gaps = 42/820 (5%)

Query  3    YNHEVIERKWQHYWKEHKTFKTEEVADKDKYYVLDMFPYPSGQGLHVGHPEGYTATDIMA  62
            Y+H  IE KWQ +W ++ TFKT   A K K+Y LDMFPYPSG GLHVGHPEGYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMKRMQGKNVLHPMGWDAFGLPAEQYALKTGHNPRDFTAKNIKTFKRQIRSLGFSYDWDR  122
            R KR QG NVLHPMGWDAFGLPAEQYA+ TG++P +FTA NI  FKRQI +LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EINTTDPSYYKWTQWIFEELYKRGLAYEDNIEVNWAPDFMGGTVVANEEVVDGKTERGGY  182
            E+NTTDP+YYKWTQWIF  LY +GLAYE ++ VNW  + +G ++  +E + DG +ERGGY
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEE-LGTAIANEEVLPDGTSERGGY  182

Query  183  PVYRVPMRQWVLKITAYAdrliddlddldWPESIKEQQRNWIGRSRGASVFFEVKGHPDD  242
            PV R PMRQW+LKITAYA+RL++DL+++DWPESIK+ QRNWIG+S GA+V F VK + D 
Sbjct  183  PVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVK-DTDK  241

Query  243  KVEVFTTRPDTLFGATYMVLAPEHELVSKITTPEQAAEVKAYQEEVSRKSDLERTDLNKD  302
               VFTTRPDTLFGATY VLAPEH LV  ITT++QA  V  Y+ + S KSDL RTDL K+
Sbjct  242  DFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKE  301

Query  303  KSGVFTGAYGINPMTGKEVPIWIGDYVLESYGTGAIMAVPAHDDRDYDFAKKFGLPIVPV  362
            K+GV TG+Y+INP+ GKE+P+WI+DYVL SYGTGAIMAVPAHD+RD +FAK+F L I+PV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  363  IEGGNTDEAAYTGDGSHFNSGFMDGMGKDDAIKAAIDWLTDHKAGHEKVNYRLRDWIFSR  422
            +EGGN +EAA+T DG H+NS+F+DG++K  AI   ++WL  +  G+E+V YRLRDW+FSR
Sbjct  362  LEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSR  421

Query  423  QRYWGEPIPVIHWEDGETTLVPEDELPLRLPKAKDIQTSGGKESPLANLDDWVNVVDKNG  482
            QRYWGEPIP+IHWEDG +T VPE ELPL LP +KDI+ SG  ESPLAN+ DW++V   +G
Sbjct  422  QRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDG  481

Query  483  RKGKRETNTMPQWAGSSWYWMRYMDPHNDQAIASPEKLKYWSPVDLYVGGAEHAVLHLLY  542
             KG+RETNTMPQWAGSSWY +RY+DPHN + +A  E LK W PVD+YVGGAEHAVLHLLY
Sbjct  482  VKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLY  541

Query  543  ARFWHKFLYDLGVVPTKEPFQKLVNQGMILGTN---------------------------  575
            ARFWHK LYDLGVVPTKEPFQKL NQGMILGT+                           
Sbjct  542  ARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETG  601

Query  576  ------HEKMSKSKGNVINPDDIVDEYGADTLRVYEMFMGPIDAAKPWSTEGIHGAYHWL  629
                    KMSKS  NV+NPDD+V++YGADTLRVYEMFMGP+DA+ +WS EG++G+   L
Sbjct  602  EELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFL  661

Query  630  DRVWRLLIDDNNHLRDRVTTINDGKLDKIYNQTVKIVSDDFEHMRFNVGISQMMVFVNDA  689
            DRV RL+   +      +T  N G LDK+YN+TVK V+++ ++M+FN +I+Q+MVFVN A
Sbjct  662  DRVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAA  715

Query  690  YKADSLPIDYMEGFVKLLSPVAPHIAEELWSLLGHDG-TITYEKWPTYDASKLVENTVQM  748
             K D L  DY  GFV+L++P APH++EELW  L   G +I+Y  WP+YD SKLVEN V++
Sbjct  716  NKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEI  775

Query  749  VVQVNGKVRSHIKVARDLDKDKVEQTAKSDENVERYLEGK  788
            VVQ++GKV++ + VA+DL ++ +++ A ++E+V+  + GK
Sbjct  776  VVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGK  815

407) LVISKB_0907 in NC_020819


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  844 bits (3196),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 523/842 (63%), Positives = 658/842 (79%), Gaps = 47/842 (5%)

Query  35   YKHQIIERKWQHYWRANHTFETSDSQTKPKYYVMDMFPYPSGQGLHVGHPEGYTATDIMA  94
            Y H  IE KWQ +W  NHTF T+   +KPK+Y +DMFPYPSG GLHVGHPEGYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  95   RLKRMQGFNVLHPMGWDAFGLPAEQYALKTGHNPKDFTAHNIKNFKRQIRSLGFSYDWSR  154
            R+KR QG NVLHPMGWDAFGLPAEQYA+ TG++P +FTA+NI NFKRQI +LGFSYDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  155  EINTTDESYYKWTQWIFEQLYKKGLAYEDKIMVNWAPDFMGGTVVANEEVI-DGKTERGG  213
            E+NTTD +YYKWTQWIF +LY KGLAYE  + VNW  ++  GT +ANEEV+ DG +ERGG
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEEL--GTAIANEEVLPDGTSERGG  181

Query  214  YPVYRVPMRQWVLKITAYAdrliddlddldwpdSIKEMQRNWIGRSEGASVFFPVDGQAD  273
            YPV R PMRQW+LKITAYA+RL++DL+++DWP+SIK+MQRNWIG+S GA+V F V  ++D
Sbjct  182  YPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVK-DTD  240

Query  274  TKIEVYTTRPDTLFGATYMVLAPEHAAVAKITTPEQADAVKAYQEAIESKSDLERTDLNK  333
              + V+TTRPDTLFGATY VLAPEHA V  ITT++QA+AV  Y+     KSDL RTDL K
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  334  DKTGVFTGAYGINPLSGKKLPIWIGDYVLSSYGTGAIMAVPAHDERDYEFATKFNLPITQ  393
            +KTGV TG+Y+INP++GK +P+WI+DYVL+SYGTGAIMAVPAHDERD EFA +FNL I  
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  394  VIEGDADTDITEAAYTGDGKHINSDFMNGMDKQTAISAAIDWLTEHDAGHKQVNFRLRDW  453
            V+EG+   ++ EAA+T DG HINSDF++G+DK +AI+  ++WL  ++ G+ +V +RLRDW
Sbjct  361  VLEGG---NVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDW  417

Query  454  IFSRQRYWGEPIPVIHWEDGETTLVPEDELPLKLPAAKQLEPSGTGESPLANLDDWVNVV  513
            +FSRQRYWGEPIP+IHWEDG +T VPE ELPL LP +K++ PSGTGESPLAN+ DW++V 
Sbjct  418  LFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT  477

Query  514  DENGRKGKRETNTMPQWAGSSWYFLRYVDPTNDQAIADPEKLKYWMPVDLYIGGAEHAVL  573
             E+G KG+RETNTMPQWAGSSWY+LRY+DP N + +AD E LK W+PVD+Y+GGAEHAVL
Sbjct  478  REDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVL  537

Query  574  HLLYARFWHKFLYDLGVVPTKEPFQKLVNQGMILGTN-----------------------  610
            HLLYARFWHK LYDLGVVPTKEPFQKL NQGMILGT+                       
Sbjct  538  HLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFH  597

Query  611  ----------HEKMSKSKGNVINPDEIVEKHGADTLRLYEMFMGPLEASKPWSTEGINGS  660
                        KMSKS  NV+NPD++VE+ GADTLR+YEMFMGPL+AS +WS EG++GS
Sbjct  598  VETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGS  657

Query  661  RRWLDRVWRLLIDDNNRLRDRVTMINDGALDKIYNQTVKTVTEDLEAMRFNVAISQLMVF  720
            R+ LDRV RL+   +      +T  N GALDK+YN+TVK+VTE+++ M+FN AI+QLMVF
Sbjct  658  RKFLDRVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVF  711

Query  721  VNEAYKVDSLPMIYMEGFVKLISPIVPHIAEELW-SLLGHDETIAYAKWPTYDAKqlved  779
            VN A K D L   Y  GFV+LI+P+ PH++EELW +L + +E+I+Y  WP+YD  +LVE+
Sbjct  712  VNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVEN  771

Query  780  vvelvvqvNGKVRAHLKVAKDATKDAIEAAALADETVQVHTDGKTVRKVIVVPGKLVNIV  839
             VE+VVQ++GKV+A L VAKD +++ ++  ALA+E VQ +  GK + KVI VP KLVNIV
Sbjct  772  DVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIV  831

Query  840  AN  841
             +
Sbjct  832  IK  833

408) leuS in NC_015759


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  842 bits (3187),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 519/838 (62%), Positives = 647/838 (78%), Gaps = 44/838 (5%)

Query  3    YQHQAVEQKWQRFWEDNQIFKTGTDQSKPKYYVLDMFPFPSGQGLHVGHPEGYTATDILA  62
            Y+H A+E KWQ FW DN+ FKTGTD SKPK+Y LDMFP+PSG GLHVGHPEGYTATDIL+
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMKRMQGFNVLHPMGFDAFGLPTEDYAIKTGANPKDVTKTNVNNFRRQMRSLGLSYDWTR  122
            R KR QG NVLHPMG DAFGLP+E+YA+ TG +P + T  N+ NF+RQ+ +LG+SYDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVNTTNPKYYKWTQWIFEQLYKKGLAYEDEMMVNWAPDYNGGTVVANEEII-NGRTERGD  181
            EVNTT+P+YYKWTQWIF +LY KGLAYE E+ VNW  +   GT +ANEE++ +G +ERG+
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEEL--GTAIANEEVLPDGTSERGG  181

Query  182  YPVYRVPMRQWVLKITEYAdrllddlddldWPEAIKEQQRNWIGRSTGASIDFKIDGYDD  241
            YPV R PMRQW+LKIT YA+RLL+DL+++DWPE+IK+ QRNWIG+STGA++ FK+ +  D
Sbjct  182  YPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKD-TD  240

Query  242  KKIEVFTTRPDTLFGASYVILAPEHDLVQEITTPAQKEAVEAFKEALSSKSDLERTDLNK  301
            K + VFTTRPDTLFGA+Y +LAPEH LV+ ITT+ Q EAV  +K   S KSDL RTDL K
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  302  DKSGIFTGSYAINPVNGAKLQIWIGDYVLASYGTGAVMAVPAHDARDYEFATKYDLPKLE  361
            +K+G+ TGSYAINPVNG  + +WI+DYVLASYGTGA+MAVPAHD RD EFA +++L  + 
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  362  VIAGGDIENEVYTGDGVHINSEFLNGLEKEAAIERMLTWLSENKIGAKKVNYRLRDWIFS  421
            V+ GG++E+  +T DG+HINS+FL+GL+K +AI +M+ WL  + +G  +V YRLRDW+FS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  422  RQRYWGEPIPVINWDDGTKSLVpeeelplrlpDAENILPTGTGESPLANIDDWVNVTDEQ  481
            RQRYWGEPIP+I+W+DGT + VPE ELPL LP + +I P+GTGESPLAN+ DW++VT E+
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  482  GRHGRRETNTMPQWAGSSWYYLRYMDPHNDEMMVDPELEQYWQNVDLYVGGAEHAVLHLL  541
            G  GRRETNTMPQWAGSSWYYLRY+DPHN E + D EL + W  VD+YVGGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  542  YARFWHKVLYDLGIVTTKEPFQKLANQGMILGSN--------------------------  575
            YARFWHKVLYDLG+V TKEPFQKL NQGMILG++                          
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  576  -------HEKMSKSKGNVVNPDDVVEKYGADTLRLYEMFMGPLEQSIAWSEDGLSGSRRW  628
                     KMSKS  NVVNPDDVVE+YGADTLR+YEMFMGPL+ SIAWSE+GL GSR+ 
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  629  LDRVWRLVIDDENHLRDHITTVNDHKLDKVYNETVKKVTEHFTNMRFNTGISQLMVFVNE  688
            LDRV RL+   E      IT  N   LDKVYNETVK VTE+  +M+FNT+I+QLMVFVN 
Sbjct  661  LDRVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNA  714

Query  689  AYKVDNLPAEYIEGFIQLLSPVAPHISEELWSYF-HKDESIQMTTWPTYDESKLVEATVE  747
            A K D+L ++Y  GF+QL++P APH++EELW  +   +ESI    WP+YDESKLVE  VE
Sbjct  715  ANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVE  774

Query  748  IVFQVNGKLRGKAQMDKDSTKEEMIAAALANEGVQRTLDGQEPKKVIAVPGKLVSVVM  805
            IV Q++GK+++K  + KD ++EE+   ALANE VQ  + G++  KVIAVP KLV++V+
Sbjct  775  IVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

409) leuS in NC_009513


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  840 bits (3179),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 503/814 (62%), Positives = 633/814 (78%), Gaps = 42/814 (5%)

Query  3    YDHKTIEKKWQKFWKKNETFKADLNKDQKKYYALDMFPYPSGQGLHVGHPEGYTATDVMS  62
            YDH +IE KWQ FW  N+TFK++ +  + K+YALDMFPYPSG GLHVGHPEGYTATD++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMKRMQGFNVLHPMGWDAFGLPAEQYALKTGHNPKDFTNKNIDHFRDQIQSLGFSYDWDR  122
            R KR QG NVLHPMGWDAFGLPAEQYA+ TG++P +FT  NI +F+ QI++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVNTTDPKFYKWTQWIFEQLYKKGLAYESEIMVNWAPDFMGGTVVANEEVEDGKTKRGGY  182
            EVNTTDP++YKWTQWIF +LY KGLAYE+E+ VNW  + +G ++  +E + DG + RGGY
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEE-LGTAIANEEVLPDGTSERGGY  182

Query  183  PVYRKPMRQWVLKITAYADRLIDDLDLVDWPESVKEMQRNWIGRSEGASVFFPVVGDEDT  242
            PV RKPMRQW+LKITAYA+RL++DL+ VDWPES+K+MQRNWIG+S GA+V F V  D D 
Sbjct  183  PVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKV-KDTDK  241

Query  243  KIEVFTTRADTLFGASYVVLAPEQELVDQLTTPEHKAEVEKYKEEASRRSDLERTDLNKD  302
             + VFTTR+DTLFGA+Y VLAPE+ LVD +TT+++   V  YK +AS +SDL RTDL K+
Sbjct  242  DFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKE  301

Query  303  KTGVFTGSYVINPVNGEKLPIWISDYVLASYGTGAVMAVPSGDQRDYDFATKFNLPIKPI  362
            KTGV TGSY INPVNG  +P+WI+DYVLASYGTGA+MAVP+ D+RD +FA +FNL I P+
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  363  IEGADISEGAFDGDGKHINSGFLDGLNIADAKQKMIDWLEEHDAGHKKVNYRLRDWIFSR  422
            +EG+++ E+AF  DG HINS+FLDGL+ A A  KM++WLE ++ G+ +V YRLRDW+FSR
Sbjct  362  LEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSR  421

Query  423  QRYWGEPIPVIHWDDGTTSLVpedelplelpKTDNIEPSGTGESPLANVEDWVNVYDENG  482
            QRYWGEPIP+IHW+DGT++ VPE ELPL LP T +I PSGTGESPLANV DW++V  E+G
Sbjct  422  QRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDG  481

Query  483  RHGLRETNTMPQWAGSSWYWLRYTDPHNDEEFASKEALDYWSPVDLYVGGAEHAVLHLLY  542
              G RETNTMPQWAGSSWY LRY DPHN E +A  E L  W PVD+YVGGAEHAVLHLLY
Sbjct  482  VKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLY  541

Query  543  ARFWHKVLYDLGLVPTKEPFMKLVNQGMILGSN---------------------------  575
            ARFWHKVLYDLG+VPTKEPF KL NQGMILG++                           
Sbjct  542  ARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETG  601

Query  576  ------HEKMSKSKGNVVNPDDIVDQYGADTLRLYEMFMGPLEESVPWDEKGLHGANKWV  629
                    KMSKS  NVVNPDD+V+QYGADTLR+YEMFMGPL+ S++W E GL+G+ K +
Sbjct  602  EELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFL  661

Query  630  QRVWRLLMDDNNHLRDRVSTFNDGKLTKVYNQTVKKVTEDYERMHFNTAISQLMVFVNEA  689
            +RV RL+   +      ++  N G L KVYN+TVK VTE+ ++M FNTAI+QLMVFVN A
Sbjct  662  DRVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAA  715

Query  690  YKVDDLPVEYMKGFVKMIAPIMPHMAEELWSQF-GESDTITYQPWPTYDPKALVEDEVEM  748
             K D L  +Y KGFV++IAP+ PH++EELW  + + +++I+Y PWP+YD   LVE++VE+
Sbjct  716  NKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEI  775

Query  749  IVQVNGKVRAKIKMAKDTDRDEAQQLALANEHVK  782
            +VQ++GKV+AK+ +AKD  R+E Q++ALANE V+
Sbjct  776  VVQIKGKVKAKLVVAKDLSREELQEVALANEKVQ  809

410) leuS in NC_021494


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  840 bits (3182),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 504/814 (62%), Positives = 633/814 (78%), Gaps = 42/814 (5%)

Query  3    YDHKTIEKKWQKFWKKNETFKADLNKDQKKYYALDMFPYPSGQGLHVGHPEGYTATDVMS  62
            YDH +IE KWQ FW  N+TFK++ +  + K+YALDMFPYPSG GLHVGHPEGYTATD++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMKRMQGFNVLHPMGWDAFGLPAEQYALKTGHNPKDFTNKNIDHFRDQIQSLGFSYDWDR  122
            R KR QG NVLHPMGWDAFGLPAEQYA+ TG++P +FT  NI +F+ QI++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVNTTDPKFYKWTQWIFEQLYKKGLAYESEIMVNWAPDFMGGTVVANEEVEDGKTKRGGY  182
            EVNTTDP++YKWTQWIF +LY KGLAYE+E+ VNW  + +G ++  +E + DG + RGGY
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEE-LGTAIANEEVLPDGTSERGGY  182

Query  183  PVYRKPMRQWVLKITAYADRLIDDLDLVDWPESVKEMQRNWIGRSEGASVFFPVVGDEDT  242
            PV RKPMRQW+LKITAYA+RL++DL+ VDWPES+K+MQRNWIG+S GA+V F V  D D 
Sbjct  183  PVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKV-KDTDK  241

Query  243  KIEVFTTRADTLFGASYVVLAPEQELVDQLTTPEHKAEVEKYKEEASRRSDLERTDLNKD  302
             + VFTTR+DTLFGA+Y VLAPE+ LVD +TT+++   V  YK +AS +SDL RTDL K+
Sbjct  242  DFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKE  301

Query  303  KTGVFTGSYVINPVNGEKLPIWISDYVLASYGTGAVMAVPSGDQRDYDFATKFDLPIKPV  362
            KTGV TGSY INPVNG  +P+WI+DYVLASYGTGA+MAVP+ D+RD +FA +F+L I PV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  363  IEGADVSEGAFDGDGKHINSGFLDGLNIADAKQKMIDWLEEHDAGHKKVNYRLRDWIFSR  422
            +EG++V E+AF  DG HINS+FLDGL+ A A  KM++WLE ++ G+ +V YRLRDW+FSR
Sbjct  362  LEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSR  421

Query  423  QRYWGEPIPVIHWDDGTTSLVpedelplelpKTDNIEPSGTGESPLANVEDWVNVYDENG  482
            QRYWGEPIP+IHW+DGT++ VPE ELPL LP T +I PSGTGESPLANV DW++V  E+G
Sbjct  422  QRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDG  481

Query  483  RHGLRETNTMPQWAGSSWYWLRYTDPHNNEEFASKEALDYWSPVDLYVGGAEHAVLHLLY  542
              G RETNTMPQWAGSSWY LRY DPHN E +A  E L  W PVD+YVGGAEHAVLHLLY
Sbjct  482  VKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLY  541

Query  543  ARFWHKVLYDLGLVPTKEPFMKLVNQGMILGSN---------------------------  575
            ARFWHKVLYDLG+VPTKEPF KL NQGMILG++                           
Sbjct  542  ARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETG  601

Query  576  ------HEKMSKSKGNVVNPDDIVDQYGADTLRLYEMFMGPLEESVPWDEKGLHGANKWV  629
                    KMSKS  NVVNPDD+V+QYGADTLR+YEMFMGPL+ S++W E GL+G+ K +
Sbjct  602  EELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFL  661

Query  630  QRVWRLLMDDNNHLRDRVSTFNDGKLTKVYNQTVKKVTEDYERMHFNTAISQLMVFVNEA  689
            +RV RL+   +      ++  N G L KVYN+TVK VTE+ ++M FNTAI+QLMVFVN A
Sbjct  662  DRVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAA  715

Query  690  YKVDDLPVEYMKGFVKMIAPIMPHMAEELWSQF-GESDTITYQPWPTYDPKALVEDEVEM  748
             K D L  +Y KGFV++IAP+ PH++EELW  + + +++I+Y PWP+YD   LVE++VE+
Sbjct  716  NKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEI  775

Query  749  IVQVNGKVRAKIKMAKDTDRDEAQQLALANEHVK  782
            +VQ++GKV+AK+ +AKD  R+E Q++ALANE V+
Sbjct  776  VVQIKGKVKAKLVVAKDLSREELQEVALANEKVQ  809

411) leuS in NC_010609


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  840 bits (3179),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 503/814 (62%), Positives = 633/814 (78%), Gaps = 42/814 (5%)

Query  3    YDHKTIEKKWQKFWKKNETFKADLNKDQKKYYALDMFPYPSGQGLHVGHPEGYTATDVMS  62
            YDH +IE KWQ FW  N+TFK++ +  + K+YALDMFPYPSG GLHVGHPEGYTATD++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMKRMQGFNVLHPMGWDAFGLPAEQYALKTGHNPKDFTNKNIDHFRDQIQSLGFSYDWDR  122
            R KR QG NVLHPMGWDAFGLPAEQYA+ TG++P +FT  NI +F+ QI++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVNTTDPKFYKWTQWIFEQLYKKGLAYESEIMVNWAPDFMGGTVVANEEVEDGKTKRGGY  182
            EVNTTDP++YKWTQWIF +LY KGLAYE+E+ VNW  + +G ++  +E + DG + RGGY
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEE-LGTAIANEEVLPDGTSERGGY  182

Query  183  PVYRKPMRQWVLKITAYADRLIDDLDLVDWPESVKEMQRNWIGRSEGASVFFPVVGDEDT  242
            PV RKPMRQW+LKITAYA+RL++DL+ VDWPES+K+MQRNWIG+S GA+V F V  D D 
Sbjct  183  PVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKV-KDTDK  241

Query  243  KIEVFTTRADTLFGASYVVLAPEQELVDQLTTPEHKAEVEKYKEEASRRSDLERTDLNKD  302
             + VFTTR+DTLFGA+Y VLAPE+ LVD +TT+++   V  YK +AS +SDL RTDL K+
Sbjct  242  DFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKE  301

Query  303  KTGVFTGSYVINPVNGEKLPIWISDYVLASYGTGAVMAVPSGDQRDYDFATKFNLPIKPI  362
            KTGV TGSY INPVNG  +P+WI+DYVLASYGTGA+MAVP+ D+RD +FA +FNL I P+
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  363  IEGADISEGAFDGDGKHINSGFLDGLNIADAKQKMIDWLEEHDAGHKKVNYRLRDWIFSR  422
            +EG+++ E+AF  DG HINS+FLDGL+ A A  KM++WLE ++ G+ +V YRLRDW+FSR
Sbjct  362  LEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSR  421

Query  423  QRYWGEPIPVIHWDDGTTSLVpedelplelpKTDNIEPSGTGESPLANVEDWVNVYDENG  482
            QRYWGEPIP+IHW+DGT++ VPE ELPL LP T +I PSGTGESPLANV DW++V  E+G
Sbjct  422  QRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDG  481

Query  483  RHGLRETNTMPQWAGSSWYWLRYTDPHNDEEFASKEALDYWSPVDLYVGGAEHAVLHLLY  542
              G RETNTMPQWAGSSWY LRY DPHN E +A  E L  W PVD+YVGGAEHAVLHLLY
Sbjct  482  VKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLY  541

Query  543  ARFWHKVLYDLGLVPTKEPFMKLVNQGMILGSN---------------------------  575
            ARFWHKVLYDLG+VPTKEPF KL NQGMILG++                           
Sbjct  542  ARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETG  601

Query  576  ------HEKMSKSKGNVVNPDDIVDQYGADTLRLYEMFMGPLEESVPWDEKGLHGANKWV  629
                    KMSKS  NVVNPDD+V+QYGADTLR+YEMFMGPL+ S++W E GL+G+ K +
Sbjct  602  EELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFL  661

Query  630  QRVWRLLMDDNNHLRDRVSTFNDGKLTKVYNQTVKKVTEDYERMHFNTAISQLMVFVNEA  689
            +RV RL+   +      ++  N G L KVYN+TVK VTE+ ++M FNTAI+QLMVFVN A
Sbjct  662  DRVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAA  715

Query  690  YKVDDLPVEYMKGFVKMIAPIMPHMAEELWSQF-GESDTITYQPWPTYDPKALVEDEVEM  748
             K D L  +Y KGFV++IAP+ PH++EELW  + + +++I+Y PWP+YD   LVE++VE+
Sbjct  716  NKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEI  775

Query  749  IVQVNGKVRAKIKMAKDTDRDEAQQLALANEHVK  782
            +VQ++GKV+AK+ +AKD  R+E Q++ALANE V+
Sbjct  776  VVQIKGKVKAKLVVAKDLSREELQEVALANEKVQ  809

412) N134_07230 in NC_021872


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  839 bits (3178),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 503/814 (62%), Positives = 633/814 (78%), Gaps = 42/814 (5%)

Query  3    YDHKTIEKKWQKFWKKNETFKADLNKDQKKYYALDMFPYPSGQGLHVGHPEGYTATDVMS  62
            YDH +IE KWQ FW  N+TFK++ +  + K+YALDMFPYPSG GLHVGHPEGYTATD++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMKRMQGFNVLHPMGWDAFGLPAEQYALKTGHNPKDFTNKNIDHFRDQIQSLGFSYDWDR  122
            R KR QG NVLHPMGWDAFGLPAEQYA+ TG++P +FT  NI +F+ QI++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVNTTDPKFYKWTQWIFEQLYKKGLAYESEIMVNWAPDFMGGTVVANEEVEDGKTKRGGY  182
            EVNTTDP++YKWTQWIF +LY KGLAYE+E+ VNW  + +G ++  +E + DG + RGGY
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEE-LGTAIANEEVLPDGTSERGGY  182

Query  183  PVYRKPMRQWVLKITAYADRLIDDLDLVDWPESVKEMQRNWIGRSEGASVFFPVVGDEDT  242
            PV RKPMRQW+LKITAYA+RL++DL+ VDWPES+K+MQRNWIG+S GA+V F V  D D 
Sbjct  183  PVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKV-KDTDK  241

Query  243  KIEVFTTRADTLFGASYVVLAPEQELVDQLTTPEHKAEVEKYKEEASRRSDLERTDLNKD  302
             + VFTTR+DTLFGA+Y VLAPE+ LVD +TT+++   V  YK +AS +SDL RTDL K+
Sbjct  242  DFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKE  301

Query  303  KTGVFTGSYVINPVNGEKLPIWISDYVLASYGTGAVMAVPSGDQRDYDFATKFDLPIKPV  362
            KTGV TGSY INPVNG  +P+WI+DYVLASYGTGA+MAVP+ D+RD +FA +F+L I PV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  363  IEGADVSEGAFDGDGKHINSGFLDGLNIADAKQKMIDWLEEHDAGHKKVNYRLRDWIFSR  422
            +EG++V E+AF  DG HINS+FLDGL+ A A  KM++WLE ++ G+ +V YRLRDW+FSR
Sbjct  362  LEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSR  421

Query  423  QRYWGEPIPVIHWDDGTTSLVpedelplelpKTDNIEPSGTGESPLANVEDWVNVYDENG  482
            QRYWGEPIP+IHW+DGT++ VPE ELPL LP T +I PSGTGESPLANV DW++V  E+G
Sbjct  422  QRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDG  481

Query  483  RHGLRETNTMPQWAGSSWYWLRYTDPHNDEEFASKEALDYWSPVDLYVGGAEHAVLHLLY  542
              G RETNTMPQWAGSSWY LRY DPHN E +A  E L  W PVD+YVGGAEHAVLHLLY
Sbjct  482  VKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLY  541

Query  543  ARFWHKVLYDLGLVPTKEPFMKLVNQGMILGSN---------------------------  575
            ARFWHKVLYDLG+VPTKEPF KL NQGMILG++                           
Sbjct  542  ARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETG  601

Query  576  ------HEKMSKSKGNVVNPDDIVDQYGADTLRLYEMFMGPLEESVPWDEKGLHGANKWV  629
                    KMSKS  NVVNPDD+V+QYGADTLR+YEMFMGPL+ S++W E GL+G+ K +
Sbjct  602  EELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFL  661

Query  630  QRVWRLLMDDNNHLRDRVSTFNDGKLTKVYNQTVKKVTEDYERMHFNTAISQLMVFVNEA  689
            +RV RL+   +      ++  N G L KVYN+TVK VTE+ ++M FNTAI+QLMVFVN A
Sbjct  662  DRVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAA  715

Query  690  YKVDDLPVEYMKGFVKMIAPIMPHMAEELWSQF-GESDTITYQPWPTYDPKALVEDEIEM  748
             K D L  +Y KGFV++IAP+ PH++EELW  + + +++I+Y PWP+YD   LVE+++E+
Sbjct  716  NKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEI  775

Query  749  IVQVNGKVRAKIKMAKDTDRDEAQQLALANEHVK  782
            +VQ++GKV+AK+ +AKD  R+E Q++ALANE V+
Sbjct  776  VVQIKGKVKAKLVVAKDLSREELQEVALANEKVQ  809

413) Spico_0089 in NC_015436


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  838 bits (3172),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 490/840 (59%), Positives = 653/840 (78%), Gaps = 9/840 (1%)

Query  5    MSTYSFNEIEKKWQKFWEEHKTFLAKEDPSFPPEKRQYVLDMFPYPSAEGLHVGHPEGYT  64
            M+ Y    IE KWQ FW ++ TF +  D+S P   + Y LDMFPYPS+ GLHVGHPEGYT
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKP---KFYALDMFPYPSGAGLHVGHPEGYT  57

Query  65   ATDIYCRFLRMNGYNVLHPMGFDSFGLPAETYALKTGIHPRVTTEASIANFRKQIKSLGF  124
            ATDI  RF R +G NVLHPMG D+FGLPAE YA+ TG +P   T  +IANF++QI++LGF
Sbjct  58   ATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGF  117

Query  125  SYDWDREISTHEPEYYRWTQWIFEQLYKMGLAYESEMPVNWCSHDNAVLSNEEV-KEGRC  183
            SYDWDRE++T +P+YY+WTQWIF +LY  GLAYE+E+PVNW  +  + ++NEEV  +G  
Sbjct  118  SYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTS  177

Query  184  ERCGTPVIRRNIRQWVLKITAYADRLIDDLDGLDWPESVKQMQRNWIGRSEGASVFFKVD  243
            ER G PV+R+ +RQW+LKITAYA+RL++DL+ +DWPES+K+MQRNWIG+S GA+V FKV 
Sbjct  178  ERGGYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVK  237

Query  244  GHNENLEVYTTRCDTLFGATYMVISPEHPLVGKLTAPDRKKEVEAYIHQAAHKSDLERTD  303
            + + ++ V+TTR DTLFGATY V++PEH+LV+ +T++D+   V  Y +QA+ KSDL RTD
Sbjct  238  DTDKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTD  297

Query  304  LAKDKTGVFSGSYAVNPVNGERIPIWIADYVLISYGTGAIMAVPAHDTRDWEFAKKFNLP  363
            LAK+KTGV +GSYA+NPVNG  +P+WIADYVL SYGTGAIMAVPAHD RDWEFAK+FNL 
Sbjct  298  LAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLD  357

Query  364  IIEVLKGEGDVQEAAWIEDGIHVNSGFLDGLDKEDAIATMLSWLEKNKLGHKTTNYKLRD  423
            II VL G G+V+EAA  EDG+H+NS+FLDGLDK  AIA M+ WLE + +G+    Y+LRD
Sbjct  358  IIPVLEG-GNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  424  WIFSRQRYWGEPIPLVHTRDGAVELIPENQLPLLLPEIERYQPASTGESPLANVTEWVET  483
            W+FSRQRYWGEPIP++H  DG+   +PE++LPL+LP     +P++TGESPLANVT+W+E 
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  484  QSPVDGSPARRETNTMPQWAGSCWYFLRYLDPHNSERFVSKEAEEYWMPVDLYVGGAEHA  543
             +  DG  +RRETNTMPQWAGS WY+LRY+DPHN+E++   E    W+PVD+YVGGAEHA
Sbjct  477  -TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  544  VLHLLYARFWHKVLYDLGHVSTKEPFQRLVNQGMITSFAYQRPDKSLVPTDMVEELPDGS  603
            VLHLLYARFWHKVLYDLG V+TKEPFQ+L NQGMI + +Y+ +  +LV+TD VE   DGS
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEK-RDGS  594

Query  604  FMEKQTGIALERVIAKMSKSLKNVINPDDIVREYGADTMRMYEMFMGPLRESKPWATTSL  663
            F + +TG  LE+  AKMSKSLKNV+NPDD+V +YGADT+R+YEMFMGPL  S +W+  +L
Sbjct  595  FFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGL  654

Query  664  IGIWRFLDRIWRLHEDRAISEEAPSAELLKTLHKTIKKVTTDTEALNFNTAISQMMVLVN  723
             G ++FLDR+ RL   + I+EE ++A L K  + T+K VT + + ++FNTAI+Q+MV+VN
Sbjct  655  EGSRKFLDRVYRLITTKEITEENSGA-LDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVN  713

Query  724  EMYKCDVLPREVWESLLLLLSPYVPHIAEELWER-AGHTPSIAYASWPTYAEELTQDDEV  782
               K D L  +   +++ L++P+ PH++EELW+  ++   SI+Y +WP+Y E    +++V
Sbjct  714  AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDV  773

Query  783  ELVIQVNGKLRARVVVAKGLSRDEALATARANEVVKGWIEGKPIVKEIFVQDKLVNIVVK  842
            E+V+Q++GK++A++VVAK+LSR+E    A ANE V++ I GK I+K I V +KLVNIV+K
Sbjct  774  EIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

414) leuS in NC_015697


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  837 bits (3168),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 501/814 (62%), Positives = 631/814 (78%), Gaps = 42/814 (5%)

Query  3    YNHKTIEKKWQKFWKKNETFKADLNKDQKKYYALDMFPYPSGQGLHVGHPEGYTATDVMS  62
            Y+H +IE KWQ FW  N+TFK++ +  + K+YALDMFPYPSG GLHVGHPEGYTATD++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RMKRMQGFNVLHPMGWDAFGLPAEQYALKTGHNPKDFTNKNIDHFRDQIQSLGFSYDWDR  122
            R KR QG NVLHPMGWDAFGLPAEQYA+ TG++P +FT  NI +F+ QI++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVNTTDPKFYKWTQWIFEQLYKKGLAYESEIMVNWAPDFMGGTVVANEEVEDGKTKRGGY  182
            EVNTTDP++YKWTQWIF +LY KGLAYE+E+ VNW  + +G ++  +E + DG + RGGY
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEE-LGTAIANEEVLPDGTSERGGY  182

Query  183  PVYRKPMRQWVLKITAYADRLIDDLDLVDWPESVKEMQRNWIGRSEGASVFFPVVGDEDT  242
            PV RKPMRQW+LKITAYA+RL++DL+ VDWPES+K+MQRNWIG+S GA+V F V  D D 
Sbjct  183  PVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKV-KDTDK  241

Query  243  KIEVFTTRADTLFGASYVVLAPEQELVDQLTTPEHKAEVEKYKEEASRRSDLERTDLNKD  302
             + VFTTR+DTLFGA+Y VLAPE+ LVD +TT+++   V  YK +AS +SDL RTDL K+
Sbjct  242  DFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKE  301

Query  303  KTGVFTGSYVINPVNGEKLPIWISDYVLASYGTGAVMAVPSGDQRDYDFATKFDLPIKPV  362
            KTGV TGSY INPVNG  +P+WI+DYVLASYGTGA+MAVP+ D+RD +FA +F+L I PV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  363  IEGTDVSEGAFDGDGKHINSGFLDGLNIADAKQKMIDWLEEHDAGHKKVNYRLRDWIFSR  422
            +EG +V E+AF  DG HINS+FLDGL+ A A  KM++WLE ++ G+ +V YRLRDW+FSR
Sbjct  362  LEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSR  421

Query  423  QRYWGEPIPVIHWDDGTTSLVpedelplelpKTDNIEPSGTGESPLANVEDWVNVYDENG  482
            QRYWGEPIP+IHW+DGT++ VPE ELPL LP T +I PSGTGESPLANV DW++V  E+G
Sbjct  422  QRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDG  481

Query  483  RHGLRETNTMPQWAGSSWYWLRYTDPHNDKEFASKEALDYWSPVDLYVGGAEHAVLHLLY  542
              G RETNTMPQWAGSSWY LRY DPHN   +A  E L  W PVD+YVGGAEHAVLHLLY
Sbjct  482  VKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLY  541

Query  543  ARFWHKVLYDLGLVPTKEPFMKLVNQGMILGSN---------------------------  575
            ARFWHKVLYDLG+VPTKEPF KL NQGMILG++                           
Sbjct  542  ARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETG  601

Query  576  ------HEKMSKSKGNVVNPDDIVDQYGADTLRLYEMFMGPLEESVPWDEKGLHGANKWV  629
                    KMSKS  NVVNPDD+V+QYGADTLR+YEMFMGPL+ S++W E GL+G+ K +
Sbjct  602  EELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFL  661

Query  630  QRVWRLLMDDNNHLRDRVSTFNDGKLTKVYNQTVKKVTEDYERMHFNTAISQLMVFVNEA  689
            +RV RL+   +      ++  N G L KVYN+TVK VTE+ ++M FNTAI+QLMVFVN A
Sbjct  662  DRVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAA  715

Query  690  YKVDDLPVEYMKGFVKMIAPIMPHMAEELWSQF-GESDTITYQSWPTYDPKALVEDEVEM  748
             K D L  +Y KGFV++IAP+ PH++EELW  + + +++I+Y +WP+YD   LVE++VE+
Sbjct  716  NKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEI  775

Query  749  IVQVNGKVRAKIKMAKDTDRDEAQQLALANEHVK  782
            +VQ++GKV+AK+ +AKD  R+E Q++ALANE V+
Sbjct  776  VVQIKGKVKAKLVVAKDLSREELQEVALANEKVQ  809

415) leuS in NC_012914


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  834 bits (3156),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 514/823 (63%), Positives = 642/823 (79%), Gaps = 44/823 (5%)

Query  8    YNPLAVEPKWQKYWDENKTFATTEDSGKKKFYALDMFPYPSGAGLHVGHPEGYTATDIVS  67
            Y+  A+EPKWQ +W +N TF T  D++K KFYALDMFPYPSGAGLHVGHPEGYTATDI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  68   RYKRMRGYNVLHPMGWDAFGLPAEQYALQTGRHPREITVENINNFRRQIKSLGFSYDWDR  127
            R+KR +G NVLHPMGWDAFGLPAEQYA++TG +P E+T ENI NF+RQI++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  128  EFSTTDPDYYKWTQWIFIQLYNKGLAYVAEVPVNWCPALGTVLANEEVI-DGLSERGGHP  186
            E +TTDP+YYKWTQWIF +LY+KGLAY AEVPVNW   LGT +ANEEV+ DG SERGG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  187  VIRKPMRQWMLKITEYAerlledleeldWSESIKDMQRNWIGKSTGAEVTFDIDGHDASL  246
            V+RKPMRQWMLKIT YAERLLEDLEE+DW+ESIKDMQRNWIGKSTGA+VTF + + D  +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  247  VVFTTRPDTLFGATYCVLAPEHELVATITTADQAQAVDAYKEAAARKSDLERTDLAKDKT  306
             VFTTRPDTLFGATY VLAPEH LV +ITT+DQA+AV  YK  A+ KSDL RTDLAK+KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  307  GVFTGAYAINPVNGAKTPIWIADYVLAGYGTGAIMAVPGHDTRDWEFAKQFDLPILEVVQ  366
            GV TG+YAINPVNG   P+WIADYVLA+YGTGAIMAVP+HD RDWEFAKQF+L I+ V++
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  367  GGDATKEAYAGDGPHANSDFLNGLNNEDAIKTMIEHLEGSGKGHGKVTYRLRDWLFSRQR  426
            GG+    A++ DG H NSDFL+GL++  AI  M+E LE+ G G+ +VTYRLRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  427  YWGEPIPILHLEDGTMKpvpvdqlplvlpdvdAIKPSGTGESPLANVTEWVNTIDPETGM  486
            YWGEPIPI+H EDGT  +VP  +LPLVLP    I+PSGTGESPLANVT+W++ +  E G+
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE-VTREDGV  482

Query  487  KARRETNTMPQWAGSCWYYLRFIDPKNENEICSPEKQKEWLPVDLYIGGAEHAVLHLLYA  546
            K+RRETNTMPQWAGS WYYLR+IDP N + +   E  K+WLPVD+Y+GGAEHAVLHLLYA
Sbjct  483  KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  547  RFWHKVLYDLGVVDTKEPFHKLVNQGMILGTN----------------------------  578
            RFWHKVLYDLGVV TKEPF+KL NQGMILGT+                            
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  579  -----NEKMSKSRGNVINPDDIVNEFGADTLRMYEMFMGPLEATKPWNTNGVEGTYRFLS  633
                   KMSKS  NV+NPDD+V+++GADTLR+YEMFMGPL+A+ +W+ +G+EG+ +FL 
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  634  RVWRLFVGEDGSVNAKITNDGETTKAFKQTWHRSIKKVTDDFENLRFNTAISQLMIFVNE  693
            RV RL+   + + +    N G   K +++T    +K VT++ ++++FNTAI+QLM+FVN 
Sbjct  663  RVYRLITTKEITEE----NSGALDKVYNET----VKAVTEQVDQMKFNTAIAQLMVFVNA  714

Query  694  AYKTDVLPVEAMKNFLQMLSPLAPHITEELWEKLGGTG-SITYEQWPSYEEALTVDDEVE  752
            A K D L  +  K F+Q+++P+APH+ EELW+ L ++G SI+Y  WPSY+E+  V+++VE
Sbjct  715  ANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVE  774

Query  753  IVVQVNGKIIERVSIAADTAEAEMESLAKDMDKVKELIEGKTI  795
            IVVQ++GK+  ++ +A D +  E++ +A   +KV+  I GK I
Sbjct  775  IVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDI  817

416) leuS in NC_017448


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  818 bits (3096),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 494/896 (56%), Positives = 653/896 (73%), Gaps = 64/896 (7%)

Query  1    MAKYNPQEIETKWQAYWEEHQTFKTGEDKSKPKYYCLDMFPYPSGAGLHVGHPEGYTATD  60
            M+ Y+   IE KWQA+W +++TFKTG D SKPK+Y LDMFPYPSGAGLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   IICRYKRSRGFNVLHPMGWDAFGLPAEQYAIQTGTHPAITTKKNCDNFRRQIKRLGLSYD  120
            I+ R+KR++G NVLHPMGWDAFGLPAEQYA++TG +PA  T  N  NF+RQI+ LG+SYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WNKEVNTTDPKYYKWTQWIFKRLYGTWFDEDQQKGRPIEELPIPADVEAKGKEEVRKYKD  180
            W++EVNTTDP+YYKWTQWIF +LY                                    
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYE-----------------------------------  145

Query  181  GKRLAYYADAQVWWCKHCKIVCANEEVLNDGSHEKCGTKEVERRNLKQWLMRIPlygdrl  240
             K LAY A+  V W  +     ANEEVL DG+ E+ G   V R+ ++QW+++I  Y++RL
Sbjct  146  -KGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGY-PVVRKPMRQWMLKITAYAERL  203

Query  241  lkgldkldWPQGVKDMQKNWIGKSYGAEVDFAIADAEGKPTEKKLRVYTTRCDTLFGATY  300
            L +L+ +DWP+++KDMQ+NWIGKS GA+V F +     K T+K + V+TTR DTLFGATY
Sbjct  204  LEDLEEVDWPESIKDMQRNWIGKSTGANVTFKV-----KDTDKDFTVFTTRPDTLFGATY  258

Query  301  MVVAPEHAMVPELTTAEQKVAVEEYVHAAALKSDLDRTELAKEKTGVFTGSYAVNPLTGT  360
             V+APEHA+V  +TT++Q  AV +Y + A+LKSDL RT+LAKEKTGV TGSYA+NP+ G 
Sbjct  259  AVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAINPVNGK  318

Query  361  KIPVWVADYVLTGYGTGAIMAVPAHDTRDFDFAKKFNLPVICIMEPDASCPEDVKPLVLK  420
             +PVW+ADYVL++YGTGAIMAVPAHD RD +FAK+FNL +I ++E +             
Sbjct  319  EMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNV-----------  367

Query  421  GEACWAADGTYINSENATLCLNGLNKKQGIAKVIEWLEANKIGKATVNYKLRDWLFSRQR  480
             EA  + DG  INS+     L+GL+K  +IAK++EWLEA+ +G+  V Y+LRDWLFSRQR
Sbjct  368  EEAAFTEDGLHINSD----FLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  481  YWGEPFPIIHWEDGEISTVDDAELPVLLPELKDYKPGDGGQSPLANATEWLQVVDKNGRK  540
            YWGEP+PIIHWEDG  ++V ++ELP++LP  KD +P++ G+SPLAN T+WL+V   +G K
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  541  GIRETNTMPQWAGSCWYYLRYIDACNGDAFVAKELEKYWMPVDLYVGGAEHAVLHLLYSR  600
            G RETNTMPQWAGS WYYLRYID+ N + +   EL K W+PVD+YVGGAEHAVLHLLY+R
Sbjct  484  GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYAR  543

Query  601  FWHKVLFDLGLVSTDEPFQKLFNQGMILAFAYEDAAGSKVPTDEVEEKNGKYFKKGTDIE  660
            FWHKVL+DLG+V+T EPFQKLFNQGMIL+ +Y D+ G+ V+TD VE ++G +F   T+ E
Sbjct  544  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEE  603

Query  661  LKQIVAKMSKSLKNVVNPDDVVRDYGADSLRLYEMFMGPLDAVKPWQTKGIEGMNRFLGR  720
            L Q  AKMSKSLKNVVNPDDVV +YGAD+LR+YEMFMGPLDA  +W   G+EG  +FL+R
Sbjct  604  LEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR  663

Query  721  AWRSVVGDSDEAPVFVDEAAPEAIEKVMHQSVIKVTNDIENMSFNTAISQLMIFNNEMMK  780
              R +          + E  + A++KV +++V  VT+++++M FNTAI+QLM+F N   K
Sbjct  664  VYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANK  717

Query  781  MDKRYREPCETFVKLLHPFAPHIAEEMWSIL-GHNESLTNVAWPEADHSKAVENTVEVVF  839
             DK + +    FV+L+ PFAPH++EE+W  L +  ES++ V+WP  D+SK VEN VE+V 
Sbjct  718  EDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVV  777

Query  840  QVNGKVRAKASVAKDMDKAALEKLAMDNDRVKEFMAGKTVVKSIVVPGKLVNIVVK  895
            Q++GKV+AK  VAKD+ +  L+ +A+ N++V+  +AGK ++K I VP KLVNIV+K
Sbjct  778  QIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

417) Fisuc_1159 in NC_013410


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  818 bits (3096),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 494/896 (56%), Positives = 653/896 (73%), Gaps = 64/896 (7%)

Query  1    MAKYNPQEIETKWQAYWEEHQTFKTGEDKSKPKYYCLDMFPYPSGAGLHVGHPEGYTATD  60
            M+ Y+   IE KWQA+W +++TFKTG D SKPK+Y LDMFPYPSGAGLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   IICRYKRSRGFNVLHPMGWDAFGLPAEQYAIQTGTHPAITTKKNCDNFRRQIKRLGLSYD  120
            I+ R+KR++G NVLHPMGWDAFGLPAEQYA++TG +PA  T  N  NF+RQI+ LG+SYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WNKEVNTTDPKYYKWTQWIFKRLYGTWFDEDQQKGRPIEELPIPADVEAKGKEEVRKYKD  180
            W++EVNTTDP+YYKWTQWIF +LY                                    
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYE-----------------------------------  145

Query  181  GKRLAYYADAQVWWCKHCKIVCANEEVLNDGSHEKCGTKEVERRNLKQWLMRIPlygdrl  240
             K LAY A+  V W  +     ANEEVL DG+ E+ G   V R+ ++QW+++I  Y++RL
Sbjct  146  -KGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGY-PVVRKPMRQWMLKITAYAERL  203

Query  241  lkgldkldWPQGVKDMQKNWIGKSYGAEVDFAIADAEGKPTEKKLRVYTTRCDTLFGATY  300
            L +L+ +DWP+++KDMQ+NWIGKS GA+V F +     K T+K + V+TTR DTLFGATY
Sbjct  204  LEDLEEVDWPESIKDMQRNWIGKSTGANVTFKV-----KDTDKDFTVFTTRPDTLFGATY  258

Query  301  MVVAPEHAMVPELTTAEQKVAVEEYVHAAALKSDLDRTELAKEKTGVFTGSYAVNPLTGT  360
             V+APEHA+V  +TT++Q  AV +Y + A+LKSDL RT+LAKEKTGV TGSYA+NP+ G 
Sbjct  259  AVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAINPVNGK  318

Query  361  KIPVWVADYVLTGYGTGAIMAVPAHDTRDFDFAKKFNLPVICIMEPDASCPEDVKPLVLK  420
             +PVW+ADYVL++YGTGAIMAVPAHD RD +FAK+FNL +I ++E +             
Sbjct  319  EMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNV-----------  367

Query  421  GEACWAADGTYINSENATLCLNGLNKKQGIAKVIEWLEANKIGKATVNYKLRDWLFSRQR  480
             EA  + DG  INS+     L+GL+K  +IAK++EWLEA+ +G+  V Y+LRDWLFSRQR
Sbjct  368  EEAAFTEDGLHINSD----FLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  481  YWGEPFPIIHWEDGEISTVDDAELPVLLPELKDYKPGDGGQSPLANATEWLQVVDKNGRK  540
            YWGEP+PIIHWEDG  ++V ++ELP++LP  KD +P++ G+SPLAN T+WL+V   +G K
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  541  GIRETNTMPQWAGSCWYYLRYIDACNGDAFVAKELEKYWMPVDLYVGGAEHAVLHLLYSR  600
            G RETNTMPQWAGS WYYLRYID+ N + +   EL K W+PVD+YVGGAEHAVLHLLY+R
Sbjct  484  GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYAR  543

Query  601  FWHKVLFDLGLVSTDEPFQKLFNQGMILAFAYEDAAGSKVPTDEVEEKNGKYFKKGTDIE  660
            FWHKVL+DLG+V+T EPFQKLFNQGMIL+ +Y D+ G+ V+TD VE ++G +F   T+ E
Sbjct  544  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEE  603

Query  661  LKQIVAKMSKSLKNVVNPDDVVRDYGADSLRLYEMFMGPLDAVKPWQTKGIEGMNRFLGR  720
            L Q  AKMSKSLKNVVNPDDVV +YGAD+LR+YEMFMGPLDA  +W   G+EG  +FL+R
Sbjct  604  LEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR  663

Query  721  AWRSVVGDSDEAPVFVDEAAPEAIEKVMHQSVIKVTNDIENMSFNTAISQLMIFNNEMMK  780
              R +          + E  + A++KV +++V  VT+++++M FNTAI+QLM+F N   K
Sbjct  664  VYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANK  717

Query  781  MDKRYREPCETFVKLLHPFAPHIAEEMWSIL-GHNESLTNVAWPEADHSKAVENTVEVVF  839
             DK + +    FV+L+ PFAPH++EE+W  L +  ES++ V+WP  D+SK VEN VE+V 
Sbjct  718  EDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVV  777

Query  840  QVNGKVRAKASVAKDMDKAALEKLAMDNDRVKEFMAGKTVVKSIVVPGKLVNIVVK  895
            Q++GKV+AK  VAKD+ +  L+ +A+ N++V+  +AGK ++K I VP KLVNIV+K
Sbjct  778  QIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

418) Spirs_0283 in NC_014364


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  812 bits (3075),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 463/836 (56%), Positives = 618/836 (74%), Gaps = 39/836 (4%)

Query  4    MSKYPFADIEKKWQDYWERNKSFHVVEDPAIPPEKRVYVLDMFPYPSSQGLHVGHPEGYT  63
            M+ Y  + IE KWQ +W  N +F    D++ P   + Y LDMFPYPS+ GLHVGHPEGYT
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKP---KFYALDMFPYPSGAGLHVGHPEGYT  57

Query  64   ATDIYCRYLRMNGYNVLHPMGFDSFGLPAENYAIKTGTHPKATTESNIDMFRSQIKRLGF  123
            ATDI  R+ R +G NVLHPMG D+FGLPAE+YA+ TG +P   T  NI  F+ QI+ LGF
Sbjct  58   ATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGF  117

Query  124  SYDWDREISTHKIEYYRWTQWIFLQLFKKGLAYESQTPINWCPSCKTGLANEEV-KEGKC  182
            SYDWDRE++T   +YY+WTQWIF +L+ KGLAYE++ P+NW     T++ANEEV  +G  
Sbjct  118  SYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTS  177

Query  183  ERCGAQVTRKNIRQWILKITTYADQLLEGLEDLNWSEAIKTMQRNWIGRSEGADVVFTVE  242
            ER G  V RK +RQW+LKIT+YA++LLE+LE+++W+E+IK MQRNWIG+S GA+V F V 
Sbjct  178  ERGGYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVK  237

Query  243  GTEDEITVYTTRPDTLFGATYMVLAPEHPLVAKITTEGQKAAVQAYLDEAAKKSDLERTD  302
            +T+ ++TV+TTRPDTLFGATY VLAPEH+LV  ITT +Q  AV  Y  +A+ KSDL RTD
Sbjct  238  DTDKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTD  297

Query  303  LAKDKTGVFSGAYAVNPVNGEKIPVWIADYVLISYGSGAIMAVPAHDQRDWEFAKKFDIP  362
            LAK+KTGV +G+YA+NPVNG  +PVWIADYVL SYG+GAIMAVPAHD+RDWEFAK+F++ 
Sbjct  298  LAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLD  357

Query  363  IIRVLEGGDIESEAYTGDGVHVNSGFLDGLGKEEAIAKMLDWLEERKLGKRSINYKLRDW  422
            II VLEGG++E  A+T DG+H+NS+FLDGL+K  AIAKM++WLE   +G+ ++ Y+LRDW
Sbjct  358  IIPVLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDW  417

Query  423  IFSRQRYWGEPIPIVHCEKCGVVPLAEEDLPLTLPEVESYAPTGTGESPLAAINEWVNTT  482
            +FSRQRYWGEPIPI+H E     +++E +LPL LP      P+GTGESPLA + +W++ T
Sbjct  418  LFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT  477

Query  483  CPKCGGPAKRETNTMPQWAGSCWYYLRYLDPHNDKKFASRDKIDYWMPVDLYVGGAEHAV  542
                G  ++RETNTMPQWAGS WYYLRY+DPHN  K+A  + +  W+PVD+YVGGAEHAV
Sbjct  478  RED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  543  LHLLYSRFWHKVLHEIGAVNTTEPFQRLVNQGMILG------------------------  578
            LHLLY+RFWHKVL ++G V T EPFQ+L NQGMILG                        
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFF  596

Query  579  ---------EGGVKMSKSLGNVINPDDIIKEYGADSMRVYEMFMGPLQVSKPWSTNGLAG  629
                     ++  KMSKSL NV+NPDD++ +YGAD++RVYEMFMGPL+ S +WS +GL G
Sbjct  597  HVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEG  656

Query  630  VHRFLDRVWRLGERDVIDGPAPDDQKKILHQTIRKVSQDTAALEFNTAIAQMMIFINEMF  689
             ++FLDRV RL     I    ++   K+ ++T++ V+++   + FNTAIAQ+M+F+N   
Sbjct  657  SRKFLDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  690  KSEKLYREIWEPFVLIIAPYAPHLAEELWDRL-GHNETLAYEPWPQWDEALCQENETEVV  748
            K +KL+ +    FV +IAP+APHL+EELW+ L +  E+++Y PWP  DE+   EN+ E+V
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  749  FQVNGKVRAKCMLPVGMAKEELEKQAMANERIQELIDGKRVMKVIAVPDKLVNIVI  804
             Q++GKV+AK +++ ++++EEL+  A+ANE++Q  I GK ++KVIAVP+KLVNIVI
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

419) SpiBuddy_0042 in NC_015152


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  808 bits (3060),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 472/840 (57%), Positives = 639/840 (77%), Gaps = 9/840 (1%)

Query  5    MSKYPFHEIETKWQAYWDEHQTFAVTEDPSIPKDKRAYVLDMFPYPSGAGLHVGHPEGYT  64
            M+ Y    IE KWQA+W +++TF    D+S PK    Y LDMFPYPSGAGLHVGHPEGYT
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPK---FYALDMFPYPSGAGLHVGHPEGYT  57

Query  65   ATDIYCRFLRMRGYNVLHPMGFDSFGLPAENYAIKTGTHPKATTEKNIENFRKQIKSLGF  124
            ATDI  RF R +G NVLHPMG D+FGLPAE+YA+ TG +P   T  NI NF++QI++LGF
Sbjct  58   ATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGF  117

Query  125  SYDWNREISTHSSDYYRWTQWIFIQLFNKGLAYESHTPINWCGQCKTGLANEEV-KDGKC  183
            SYDW+RE++T  ++YY+WTQWIF +L++KGLAYE++ P+NW  +  T++ANEEV  DG  
Sbjct  118  SYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTS  177

Query  184  ERCGTTVVRKNIRQWVLKITEYADKLLSDLDSVDWPESVKLMQRNWIGRSEGASVFFKVD  243
            ER G  VVRK +RQW+LKIT YA++LL DL+ VDWPES+K MQRNWIG+S GA+V FKV 
Sbjct  178  ERGGYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVK  237

Query  244  EIDAQLEVYTTRADTLYGATYMVVAPEHPLVSQLTKVGQKAAVEAYLEASARKSDLERTD  303
            + D ++ V+TTR+DTL+GATY V+APEH+LV  +T  +Q  AV  Y   ++ KSDL RTD
Sbjct  238  DTDKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTD  297

Query  304  LAKDKTGVFSGSYAINPVNGKRIPIWIADYVLISYGTGAIMAVPAHDTRDWEFAKKFNLP  363
            LAK+KTGV +GSYAINPVNGK +P+WIADYVL SYGTGAIMAVPAHD RDWEFAK+FNL 
Sbjct  298  LAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLD  357

Query  364  IIEVLKSEVDVQTQAWTEDGIHVNSDFLDGLNKEDAIEAMLAWLLERKLGSKAINYKLRD  423
            II VL +  +V+  A TEDG+H+NSDFLDGL+K  AI  M+ WL    +G+  + Y+LRD
Sbjct  358  IIPVLEGG-NVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  424  WIFSRQRYWGEPIPLVHCPTCGTVAVpieelplllpeVTSYEPSGTGESPLAKIDEWVHC  483
            W+FSRQRYWGEPIP++H     + AVP  ELPL+LP      PSGTGESPLA++ +W++ 
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  484  SCPVCGGEAKRETNTMPQWAGSCWYYLRYLDPKNANEFVSKEMEAYWMPVDLYVGGAEHA  543
            +    G  ++RETNTMPQWAGS WYYLRY+DP N++ +   E+   W+PVD+YVGGAEHA
Sbjct  477  TRE-DGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  544  VLHLLYARFWHKVLFDLGLVSTSEPFKRLVNQGMITSYAFQRKDKSLVPTDMVEEQSPDV  603
            VLHLLYARFWHKVL+DLG+V+T EPF++L NQGMI + +++    +LV+TD VE +    
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGS-  594

Query  604  FIEKATGETLERVIAKMSKSLKNVINPDEIITEFGADSMRMYEMFMGPLEVSKPWATTGL  663
            F++  TGE LE+  AKMSKSLKNV+NPD+++ ++GAD++R+YEMFMGPL+ S +W+  GL
Sbjct  595  FFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGL  654

Query  664  VGVYRFLDRIWRLFDEREITDAEPDEELKRTLHKSIKKVTYDTNSLNFNTAISQMMVLVN  723
             G  +FLDR+ RL+  +EIT+ E    L +  + ++K VT + + ++FNTAI+Q+MV+VN
Sbjct  655  EGSRKFLDRVYRLITTKEITE-ENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVN  713

Query  724  ELYKIEILPREVGETLVKLLGPYVPHLAEELWERLGHSG-GLSTVAWPAYCEEFTIDNQI  782
               K + L  + +  +V+L++P+ PHL+EELW+ L  SG ++S V+WP+Y E   ++N++
Sbjct  714  AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDV  773

Query  783  EMVFQVNGKVRSKVTVPKGLGKDEVLSMAKEDEKMRNWLEGKTIVKEIVVPDKLVNIVVK  842
            E+V Q++GKV++K+ V+K+L+++E+  +A  +EK++  + GK I+K I VP+KLVNIV+K
Sbjct  774  EIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

420) SpiGrapes_1871 in NC_016633


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  794 bits (3005),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 480/840 (58%), Positives = 645/840 (77%), Gaps = 9/840 (1%)

Query  5    MSKYPFHEIETKWQKYWEENQTFAVTEDISVPPEKRKYVLDMFPYPSGAGLHVGHPEGYT  64
            M+ Y    IE KWQ +W +N+TF    D S P   + Y LDMFPYPSGAGLHVGHPEGYT
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKP---KFYALDMFPYPSGAGLHVGHPEGYT  57

Query  65   ATDIYCRYLRMNGYNVLHPMGFDSFGLPAENYAIKTGTHPKATTEKNIENFRKQIKSLGF  124
            ATDI  R+ R +G NVLHPMG D+FGLPAE+YA+ TG +P   T  NI NF++QI++LGF
Sbjct  58   ATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGF  117

Query  125  CYDWNREISTHSSEYYRWTQWIFLQLFNKGLAYESQTPINWCPQCLTGLANEEV-KDGKC  183
             YDW+RE++T  ++YY+WTQWIF +L++KGLAYE++ P+NW  +  T++ANEEV  DG  
Sbjct  118  SYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTS  177

Query  184  ERCGTRVVRKNIRQWVLKItdyadklladldtldWPESVKSMQRNWIGRSEGAsvffkle  243
            ER G  VVRK +RQW+LKIT YA++LL DL+ +DWPES+K MQRNWIG+S GA+V FK+ 
Sbjct  178  ERGGYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVK  237

Query  244  kseeklevYTTRCDTLFGATYMVVSPEHPLVATLTTSENKAAVEAYIVSSAHKSDLERTD  303
             ++  + V+TTR DTLFGATY V++PEH+LV ++TTS++  AV  Y   ++ KSDL RTD
Sbjct  238  DTDKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTD  297

Query  304  LAKDKTGVFSGSYAINPVNGKKIPIWIADYVLISYGTGAIMAVPAHDTRDWEFAKKFNLP  363
            LAK+KTGV +GSYAINPVNGK +P+WIADYVL SYGTGAIMAVPAHD RDWEFAK+FNL 
Sbjct  298  LAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLD  357

Query  364  IVEVLKGEVDVQQQAWTEDGIHVNSDFLDGLDKEEAINKMLLWLEERKLGTKTTNYKLRD  423
            I+ VL G  +V++ A TEDG+H+NSDFLDGLDK  AI KM+ WLE   +G     Y+LRD
Sbjct  358  IIPVLEGG-NVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  424  WIFSRQRYWGEPIPLIHCEHCGIVPVPETDLPLLLPEVTSYEPSGTGESPLAKIDDWVNT  483
            W+FSRQRYWGEPIP+IH E+    +VPE++LPL+LP      PSGTGESPLA++ DW++ 
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  484  TCPVCGGPAKRETNTMPQWAGSCWYYLRYIDPHNSERFIDREKELYWMPVDLYVGGAEHA  543
            T    G  ++RETNTMPQWAGS WYYLRYIDPHN+E++ D E    W+PVD+YVGGAEHA
Sbjct  477  TRE-DGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  544  VLHLLYARFWHEVLFDLGIVSTREPFQKLVNQGMITSFAFQRKDKSLVPTDMVEEKGPDL  603
            VLHLLYARFWH VL+DLG+V+T+EPFQKL NQGMI + +++    +LV+TD VE ++  +
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSF  595

Query  604  FIEKETGEELERVVAKMSKSLKNVINPDEIITEFGADSMRMYEMFMGPLEVSKPWATTGL  663
            F + ETGEELE+  AKMSKSLKNV+NPD+++ ++GAD++R+YEMFMGPL+ S +W+  GL
Sbjct  596  F-HVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGL  654

Query  664  SGVYRFLDRIWRLYEDRPISEEAPSHELLKTLHKTIKKVTYDTDTLNFNTGISQMMVLVN  723
             G  +FLDR+ RL   + I+EE ++  L K  + T+K VT + D ++FNT+I+Q+MV+VN
Sbjct  655  EGSRKFLDRVYRLITTKEITEENSG-ALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVN  713

Query  724  ELYKVETLPRIVWEALIKMLSPYVPHLAEELWEK-AGHEPSLANVAWPTYDEKLTIDSEV  782
               K + L      +++++++P+ PHL+EELW+  ++   S++ V+WP+YDE   ++++V
Sbjct  714  AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDV  773

Query  783  EMVFQINGKVRAKEVIEKGMAKDELLTMAKANEKIVSWLDGKTIVKEIVVPDKLVNIVVR  842
            E+V QI+GKV+AK V+ K+++++EL  +A ANEK+ + + GK I+K I VP+KLVNIV++
Sbjct  774  EIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

421) Hoch_6458 in NC_013440


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  794 bits (3004),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 457/856 (54%), Positives = 620/856 (73%), Gaps = 25/856 (2%)

Query  1    MAGYDHREIDAKWQALWRDEDLFATPEDRTKPKFYILDMFPYPSGAGLHVGHPKGYVATD  60
            M+ YDH  I++KWQA+W D++ F T  D +KPKFY LDMFPYPSGAGLHVGHP GY ATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   VVARAKRMMGFNVLHVMGWDSFGLPTERQAVREGRSPAEITARNVGRFKEQLENLGLSYD  120
            +++R KR  G NVLH MGWD+FGLP+E+ A+  G  PAE+TA N++ FK Q++ LG+SYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WSRELATSDEAYYRWTQWIFLKLYEKGLAYQAEVAVNWCPALGTVLANEEV-QDGKYVET  179
            W RE+ T+D  YY+WTQWIF KLYEKGLAY+AEV+VNW   LGT +ANEEV  DG     
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  180  GDPVERRSMKQWMLRITAYADRLLDGLEDLDWPEGIKEMQRHWIGRSRGAEIDFAVENHE  239
            G PV R++M+QWML+ITAYA+RLL++LE++DWPE+IK+MQR+WIG+S GA++ F V + +
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  240  GDHDGDAIRVFTTRPDTLFGCTYVVLAPEHELVAKITTEAQREAVNAYCDEVAGRSERDR  299
             D     + VFTTRPDTLFG TY VLAPEH LV  ITT  Q EAV  Y  + + +S+  R
Sbjct  241  KD-----FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLAR  295

Query  300  TTEAADADKTGVFTGAYARNPANGAKVPIWIADYVLASYGTGAVFACPAHDERDHAFAKK  359
            T      +KTGV TG+YA NP NG  +P+WIADYVLASYGTGA+ A PAHDERD  FAK+
Sbjct  296  T--DLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQ  353

Query  360  FELPIIEVVEGGSVDEAAYTGDGAHLRSEFLDGLDIAAAKQRIIAFLEEKGCGEGVVRYR  419
            F+L II V+EGG+V+EAA+T DG H+ S+FLDGLD A+A  +++  LE  G G+  V YR
Sbjct  354  FNLDIIPVLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYR  413

Query  420  LRDWLFSRQRYWGEPFPIIELEDGTVKPLPESELPVKLPPLDEYKPTEDGRPPLARAEDW  479
            LRDWLFSRQRYWGEP+PII+ EDGT  ++PESELP+ LP   + +P+  G +PLA   DW
Sbjct  414  LRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDW  473

Query  480  VQTKDPETGAPAQRETNTMPQWAGSCWYYLRFITPKLDTAAWDPGEERYWMPVDLYVGGA  539
            ++    E G  ++RETNTMPQWAGS WYYLR+I P       D    + W+PVD+YVGGA
Sbjct  474  LEVT-REDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGA  532

Query  540  EHATLHLLYSRFWHHVLYDLGLVSTPEPFQRLFNQGMIHRTSYRDAAGKYYYEEEVDKRG  599
            EHA LHLLY+RFWH VLYDLG+V+T EPFQ+LFNQGMI  TSYRD+ G     + V+KR+
Sbjct  533  EHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRD  592

Query  600  DSYVAKADGTEVFPKLEKMSKSKYNVVNPDDMCAEYGADALRLYELFMGPLEDGCEWETA  659
            +S+     G E+     KMSKS  NVVNPDD+  +YGAD+LR+YE+FMGPL+ +  W   
Sbjct  593  GSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEE  652

Query  660  GVAGTRRFLDRLYRLVVDTDSDSGTESDKLASKLVDEDTDDRELERALHAAIKKVSEAIE  719
            G+ G+R+FLDR+YRL+   +             + +E+++   L++  + ++K V+E ++
Sbjct  653  GLEGSRKFLDRVYRLITTKE-------------ITEENSG--ALDKVYNETVKAVTEQVD  697

Query  720  SLRFNTAVSEMMMFVNEATKAERVPKAWMETFVRVLAPFAPHLGEELWRRL-GHEDSLVY  778
             ++FNTA++++M+FVN A K +++       FV+++APFAPHLGEELW+ L +  +S+ Y
Sbjct  698  QMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISY  757

Query  779  APWPAYEEAKLVADTITLAVQVNGKLRSTLEVPADIGKDDAIAQAKSDDKVAKFLEGKTL  838
             PWP+Y+E+KLV + + + VQ++GK+++ L V+ D+++++    A +++KV   + GK +
Sbjct  758  VPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDI  817

Query  839  RREIYVPGRLVNLVAN  854
             + I VP +LVN+V +
Sbjct  818  IKVIAVPNKLVNIVIK  833

422) leuS in NC_022097


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  786 bits (2975),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 465/860 (55%), Positives = 622/860 (73%), Gaps = 31/860 (3%)

Query  1    MSSYPFSTIEPKWQKYWEENKTFKTTEDKNFPKERRAYILDMFPYPSGEGLHVGHPEGYS  60
            M+ Y  ++IEPKWQ +W +N TFKT  D + PK    Y LDMFPYPSG GLHVGHPEGY+
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPK---FYALDMFPYPSGAGLHVGHPEGYT  57

Query  61   ATDIYSRFLRMNGYNVLHPMGFDSFGLPAENYAIKTGTHPRLTTDKNIENFKRQIKSLGL  120
            ATDI SRF R +G NVLHPMG D+FGLPAE+YA+ TG +P   T  NI NFKRQI++LG+
Sbjct  58   ATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGF  117

Query  121  SYDWERELSTSEEDYYKWTQWIFLQLYKKGLAYEKEAPINWCPSCLTGLANEEV-KEGHC  179
            SYDW+RE++T++ +YYKWTQWIF +LY KGLAYE E P+NW     T++ANEEV  +G  
Sbjct  118  SYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTS  177

Query  180  DRCGSQVERKNLRQWILKITEYADKLLEGLENLDWPDSIKQMQRNWIGKSYGAEIDFELA  239
            +R G  V RK +RQW+LKIT YA++LLE+LE++DWP+SIK+MQRNWIGKS GA++ F + 
Sbjct  178  ERGGYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVK  237

Query  240  ASSGEKKIKVYTTRPDTLFGATYMVLAPEHQLVSEITDTEHKAAVEQYISQSAKKSDLER  299
             +  +K + V+TTRPDTLFGATY VLAPEH LV  IT +++  AV +Y  Q++ KSDL R
Sbjct  238  DT--DKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLAR  295

Query  300  TDLAKTKTGVFTGAYAINPLTGKNIPIWISDYILISYGTGAIMAVPAHDERDFEFASKFG  359
            TDLAK KTGV TG+YAINP+ GK++P+WI+DY+L SYGTGAIMAVPAHDERD EFA +F 
Sbjct  296  TDLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFN  355

Query  360  LEKIQVVASEEEWKNKGKEGDYSSIPENCTSGDGYSVNSGEFTGLTTEEAKSKITELLEK  419
            L+ I V+ +             +++ E   + DG  +NS+ + GL    A +K+ E LE 
Sbjct  356  LDIIPVLEG-------------GNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEA  402

Query  420  KGIGKKAVNYKLRDWIFSRQRYWGEPIPLVHCPHCGVVPVNEKDLPVTLPEVKSYTPAGT  479
             G+G+  V Y+LRDW+FSRQRYWGEPIP++H  +    +V E +LP+ LP  K   P+GT
Sbjct  403  EGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGT  462

Query  480  GESPLAAIDSWVNTKCPKCGAAAKRETNTMPQWAGSCWYYLRYIDPDNEKEFANKEKCDY  539
            GESPLA +  W++      G  ++RETNTMPQWAGS WYYLRYIDP+N   +A+ E    
Sbjct  463  GESPLANVTDWLEVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQ  521

Query  540  WMPVNLYIGGAEHAVLHLLYARFWHKVLYDLGLVSTEEPFKKLVNQGLITASAYMRKNKT  599
            W+PV++Y+GGAEHAVLHLLYARFWHKVLYDLG+V+T EPF+KL NQG+I +++Y     +
Sbjct  522  WLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGA  581

Query  600  LVPVDQVKKISETEFEEIATGEKLEQVIAKMSKSLKNVITPDEIIKEYGADSCRLYEMFL  659
            LV+ D+V K  +  F ++ TGE LEQ  AKMSKSLKNV+ PD+++ +YGAD+ R+YEMF+
Sbjct  582  LVATDKVEK-RDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFM  640

Query  660  GPLEVSKPWNTNGIIGVFRFLERVWNLSEREIYDTPVNDTSTEETKALTILLNKTIKKVT  719
            GPL+ S +W+ +G+ G  +FL+RV  L          ++ + E++ AL  + N T+K VT
Sbjct  641  GPLDASIAWSEEGLEGSRKFLDRVYRL-------ITTKEITEENSGALDKVYNETVKAVT  693

Query  720  EDTASLNFNTAISQMMIFVNEVSKYKKI-PRYVWYNFVKLLSPYAPHLGEELWQKLDNK-  777
            E+   ++FNTAI+Q+M+FVN  +K  K+ + Y    FV+L++P+APHLGEELWQ L    
Sbjct  694  EQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYA-KGFVQLIAPFAPHLGEELWQALTASG  752

Query  778  ESIAYSHWPMYVEKFCIDQTCTVVVQVNGKVRGKFEAEKGTSKEELEKTALLNEGAVRHI  837
            ESI+Y  WP Y E   +++   +VVQ++GKV++K+   K+ S+EEL+  AL NE    +I
Sbjct  753  ESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEI  812

Query  838  ADKPVRKVIVVPDKLVNIVI  857
            A+K + KVI VP+KLVNIVI
Sbjct  813  AGKDIIKVIAVPNKLVNIVI  832

423) Spith_0352 in NC_017583


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  779 bits (2947),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 475/844 (57%), Positives = 620/844 (74%), Gaps = 47/844 (5%)

Query  1    MKNYSFRDIEKKWQRYWLEHKTFSVKEDPSVPREKRRYVLDMFPYPSAEGLHVGHPEGYT  60
            M  Y    IE KWQ +W ++ TF    D+S P+    Y LDMFPYPS+ GLHVGHPEGYT
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPK---FYALDMFPYPSGAGLHVGHPEGYT  57

Query  61   ATDIYCRYLRMRGYQVLHPMGFDSFGLPAEIYAITTGTHPRITTERNINRFRKQIQSLGF  120
            ATDI  R+ R +G +VLHPMG D+FGLPAE YA+ TG +P   T  NI  F++QI++LGF
Sbjct  58   ATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGF  117

Query  121  SYDWDREIATHRPEYYKWTQWMFLKMYEMGLAYMAEVPVWFCEALGTVLANEEVIQTPEG  180
            SYDWDRE+ T  P+YYKWTQW+F K+YE GLAY AEVPV   E LGT +ANEEV+  P+G
Sbjct  118  SYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVL--PDG  175

Query  181  PRSERGNHPVIRKPLRQWMLRITAYADRLLEGLDKLDWPESIKTMQRNWIGRSEGADIRF  240
              SERG  PV+RKP+RQWML+ITAYA+RLLE+L+ +DWPESIK MQRNWIG+S GA++ F
Sbjct  176  T-SERGGYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTF  234

Query  241  PLKDHDGHIEVFTTRPDTVFGATYMVLAPEHPLVQKITTPEQREAVEAYVRQAQLKSDLE  300
             +KD D ++ VFTTRPDT+FGATY VLAPEH+LV+ ITT++Q EAV  Y RQA LKSDL 
Sbjct  235  KVKDTDKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLA  294

Query  301  RTDLAKEKTGVFTGAYAINPFTEREIPVWISDYILITYGTGAIMAVPAHDERDWEFAKKF  360
            RTDLAKEKTGV TG+YAINP   +E+PVWI+DY+L +YGTGAIMAVPAHDERDWEFAK+F
Sbjct  295  RTDLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQF  354

Query  361  DLPIVQVVSRNGKEEELTEAFVEEGISINSGPFSGLPTKEMKEKIIAYMEEKGIGKRAVN  420
            +L I+ V+     EE    AF E+G+ INS+ + GL       K++  +E  G+G+  V 
Sbjct  355  NLDIIPVLEGGNVEE---AAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVT  411

Query  421  YRLRDWIFSRQRYWGEPIPVVHVEGDGVQPVPYDQLPVTLPEVESYKPTGTGESPLAAIR  480
            YRLRDW+FSRQRYWGEPIP++H E++   +VP  +LP+ LP     +P+GTGESPLA + 
Sbjct  412  YRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVT  471

Query  481  EWVETTAPDGSGRKAYRETNTMPQWAGSCWYYLRYLDPHNDREFASREKIDYWMPVDLYV  540
            +W+E T  DG   K+ RETNTMPQWAGS WYYLRY+DPHN   +A  E +  W+PVD+YV
Sbjct  472  DWLEVTREDGV--KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYV  529

Query  541  GGAEHAVLHLLYARFWHKVLYDLGLVNTDEPFMRLVNQGMILG-----------------  583
            GGAEHAVLHLLYARFWHKVLYDLG+V T EPF +L NQGMILG                 
Sbjct  530  GGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVE  589

Query  584  ----------------EDGEKMSKSRGNVVNPDDIVEEYGADSLRMYEMFMGPLEATKPW  627
                            +   KMSKS  NVVNPDD+VE+YGAD+LR+YEMFMGPL+A+ +W
Sbjct  590  KRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAW  649

Query  628  STKGLVGVHRFLNRV-WDISEREITdeepdpdllkllHKTIKKVTEDTEHLRFNTAIAQM  686
            S  GL G ++FL+RV + I+ +EIT EE    L K+ + T+K VTE+ ++++FNTAIAQ+
Sbjct  650  SEEGLEGSRKFLDRVYRLITTKEIT-EENSGALDKVYNETVKAVTEQVDQMKFNTAIAQL  708

Query  687  MTYINEIYKLERVPRSLWEPFVLIIAPYAPHIAEEMWEKLGHEG-TLAYHPWPTYDEALT  745
            M ++N   K +++       FV +IAP+APH++EE+W+ L   G +++Y PWP+YDE+  
Sbjct  709  MVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKL  768

Query  746  IDEVVTVVIQVNGKVRARIEVPRDLPKEELEKRALSHERIRQWIDGKEMKKVITVPNKIV  805
            +++ V +V+Q++GKV+A++ V++DL++EEL+  AL++E+++  I GK++ KVI+VPNK+V
Sbjct  769  VENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLV  828

Query  806  NIVV  809
            NIV+
Sbjct  829  NIVI  832

424) STHERM_c03870 in NC_014484


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  778 bits (2946),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 477/844 (57%), Positives = 619/844 (74%), Gaps = 47/844 (5%)

Query  1    MKSYSFRDIEKKWQRYWLEHKTFSVKEDPSIPKEKRRYVLDMFPYPSAEGLHVGHPEGYT  60
            M  Y    IE KWQ +W ++ TF    D+S PK    Y LDMFPYPS+ GLHVGHPEGYT
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPK---FYALDMFPYPSGAGLHVGHPEGYT  57

Query  61   ATDIYCRYLRMRGYQVLHPMGFDSFGLPAEIYAITTGTHPRITTERNIERFRTQIQSLGF  120
            ATDI  R+ R +G +VLHPMG D+FGLPAE YA+ TG +P   T  NI  F+ QI++LGF
Sbjct  58   ATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGF  117

Query  121  SYDWDREIATHRPEYYKWTQWMFLKMYEMGLAYMAEVPVWFCEALGTVLANEEVIQTPEG  180
            SYDWDRE+ T  P+YYKWTQW+F K+YE GLAY AEVPV   E LGT +ANEEV+  P+G
Sbjct  118  SYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVL--PDG  175

Query  181  PRSERGNHPVIRKPLRQWMLKITAYADRLLEGLDKLDWPESIKTMQRNWIGRSEGADIRF  240
              SERG  PV+RKP+RQWMLKITAYA+RLLE+L+ +DWPESIK MQRNWIG+S GA++ F
Sbjct  176  T-SERGGYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTF  234

Query  241  PLKDHDGHIEVFTTRPDTVFGATYMVLAPEHPLVKEITTPEQREAVEAYVRQAQLKSDLE  300
             +KD D ++ VFTTRPDT+FGATY VLAPEH+LV  ITT++Q EAV  Y RQA LKSDL 
Sbjct  235  KVKDTDKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLA  294

Query  301  RTDLAKEKTGVFTGAYAVNPFTEKEIPVWISDYILITYGTGAIMAVPAHDERDWEFAKKF  360
            RTDLAKEKTGV TG+YA+NP   KE+PVWI+DY+L +YGTGAIMAVPAHDERDWEFAK+F
Sbjct  295  RTDLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQF  354

Query  361  DLPIVQVVSRDGKEEELTEAFVEEGISINSGPFSGLPTKEMKEKIIAYMEEKGIGKRAVN  420
            +L I+ V+  +  EE    AF E+G+ INS+ + GL       K++  +E  G+G+  V 
Sbjct  355  NLDIIPVLEGGNVEE---AAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVT  411

Query  421  YRLRDWIFSRQRYWGEPIPVVHVEGDGVQPVPYDQLPVTLPEVESYKPTGTGESPLATIR  480
            YRLRDW+FSRQRYWGEPIP++H E++   +VP  +LP+ LP     +P+GTGESPLA + 
Sbjct  412  YRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVT  471

Query  481  DWVETSAPDGSGRKAYRETNTMPQWAGSCWYYLRYLDPHNDREFASREKIDYWMPVDLYV  540
            DW+E +  DG   K+ RETNTMPQWAGS WYYLRY+DPHN   +A  E +  W+PVD+YV
Sbjct  472  DWLEVTREDGV--KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYV  529

Query  541  GGAEHAVLHLLYARFWHKVLYDLGLVNTDEPFMRLVNQGMILG-----------------  583
            GGAEHAVLHLLYARFWHKVLYDLG+V T EPF +L NQGMILG                 
Sbjct  530  GGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVE  589

Query  584  ----------------EDGEKMSKSRGNVVNPDDIIEEYGADSLRMYEMFMGPLEATKPW  627
                            +   KMSKS  NVVNPDD++E+YGAD+LR+YEMFMGPL+A+ +W
Sbjct  590  KRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAW  649

Query  628  STKGLVGVHRFLNRV-WDISEREITdeepdpdllkllHKTIKKVTEDTEHLRFNTAIAQM  686
            S  GL G ++FL+RV + I+ +EIT EE    L K+ + T+K VTE+ ++++FNTAIAQ+
Sbjct  650  SEEGLEGSRKFLDRVYRLITTKEIT-EENSGALDKVYNETVKAVTEQVDQMKFNTAIAQL  708

Query  687  MTYINEIYKLERVPRSLWEPFVLIIAPYAPHIAEEMWEKLGHEG-SLAYHPWPTYDEALT  745
            M ++N   K +++       FV +IAP+APH++EE+W+ L   G S++Y PWP+YDE+  
Sbjct  709  MVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKL  768

Query  746  IDEVVTVVIQVNGKVRARIEVPRDLPKEELEKRALSHERIRQWIDGKEMKKVITVPNKIV  805
            +++ V +V+Q++GKV+A++ V++DL++EEL+  AL++E+++  I GK++ KVI+VPNK+V
Sbjct  769  VENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLV  828

Query  806  NIVV  809
            NIV+
Sbjct  829  NIVI  832

425) leuS in NC_015702


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  776 bits (2938),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 451/850 (54%), Positives = 625/850 (74%), Gaps = 22/850 (2%)

Query  4    YNHKQIEKKWQKYWLDHKTYKVEIDRAKPKYYVLDMFPYPSGSGLHVGHPEGYTATDILA  63
            Y+H  IE KWQ +W D+ T+K   D +KPK+Y LDMFPYPSG+GLHVGHPEGYTATDIL+
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYKRQKGFNVLHPMGWDNFGLPAEQYAIRTGTHPAVTTKKNVENFKRQLQSLGFSYDWDR  123
            R+KR +G NVLHPMGWD FGLPAEQYA+ TG +PA  T  N+ NFKRQ+++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EISTSDPSYYKWTQWIFTKLYEKGLAYEAEMSVNFCPALGTVLANEEI-ENGRAKEGGHV  182
            E++T+DP+YYKWTQWIFTKLYEKGLAYEAE++VN    LGT +ANEE+  +G +  GG  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERRPLRQWVLKITAYAERLLQDLDLLDWPEGLKKLQANWIGRSEGVQVDFLIDGTDEKI  242
            V R+P+RQW+LKITAYAERLL+DL+ +DWPE++K +Q NWIG+S G +V F + +TD  +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  243  TVFTTCPHTLFGATYVVLAPEHPLIKQITTTAQKDAIEGYQKETASKSDFDRTEMAKNKT  302
            TVFTT P+TLFGATY VLAPEH+L+  ITT+ Q +A+ +Y+++++ KSD+ RT++AK+KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  303  GVFTGAYAINPVNQQKIPIWIADYVLINYGTGAVMAVPSHDERDFEFATQYELPFVQVID  362
            GV TG+YAINPVN + +P+WIADYVL +YGTGA+MAVP+HDERD EFA Q++L ++ V++
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  363  PELTAEDENHDQIQQAIACGKKCWTGNGKAINSQHNDFSINGLTTEQAKESVANWLESNQ  422
                      +++++A        T +G  INS   DF ++GL    A   + +WLE++ 
Sbjct  364  G---------GNVEEA------AFTEDGLHINS---DF-LDGLDKASAIAKMVEWLEAEG  404

Query  423  KGRKTISFKLRDWLFSRQRYWGEPFPLLHFEDGTIRTLDLDELPLCPPQISQYKPASDGS  482
             G   ++++LRDWLFSRQRYWGEP+P++H EDGT  ++   ELPL  P   + +P++ G 
Sbjct  405  VGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGE  464

Query  483  SPLANAPEWVFITDVKTGKAARRETNTMPQWAGSCWYYIRFCDPHNDVEAWSKEAEQYWL  542
            SPLAN  +W+ +T     K+ RRETNTMPQWAGS WYY+R+ DPHN       E  + WL
Sbjct  465  SPLANVTDWLEVTREDGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWL  523

Query  543  PVDLYVGGVEHAVLHLLYSRFWHKVLYDCGFLSTSEPFQTLRNQGLITARSFQNSLGAYV  602
            PVD+YVGG EHAVLHLLY+RFWHKVLYD G ++T EPFQ L NQG+I + S+++S GA V
Sbjct  524  PVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALV  583

Query  603  APEDVQEKEGEYFHRETGEKLKSQIEKMSKSKLNGVSPDEIIEEFGADSLRLYEMFMGPL  662
            A + V+ ++G +FH ETGE L     KMSKS  N V+PD+++E++GAD+LR+YEMFMGPL
Sbjct  584  ATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPL  643

Query  663  EKEKVWNTDAVSGCRRFLARFYDLAVSPKLTQETTVEALKLGHRLVKGVEEDIVAMQFNT  722
            +    W+ +++ G R+FL R Y L  +  +T+E +    K+ +  VK+V E++  M+FNT
Sbjct  644  DASIAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNT  703

Query  723  AIAKMMEFINDFSKLDTYPASVLKMAAQALYPFAPHLAEEIWEILGIK-ESLSYTSYPQA  781
            AIA++M F+N  +K D   +   K   Q + PFAPHL+EE+W+ L    ES+SY + P  
Sbjct  704  AIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSY  763

Query  782  EQCYLEDSTVLYVVQVNGKLRGRFELPKDQTEEQIVEAAKKDPGIQRHIAGTEIIKVIFV  841
            ++  L ++ V  VVQ++GK+++++ ++KD + E++ E A  +  +Q +IAG +IIKVI V
Sbjct  764  DESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAV  823

Query  842  PNKLLNFVVR  851
            PNKL+N+V++
Sbjct  824  PNKLVNIVIK  833

426) leuS in NC_021846


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  772 bits (2923),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 458/840 (55%), Positives = 619/840 (74%), Gaps = 47/840 (5%)

Query  3    FSHKSIEKKWQKFWEENQTFKTTNSNEK-KAYVLDMFPYPSGAGLHVGHPKGYTATDIFA  61
            + H +IE KWQ FW +N+TFKT     K K Y LDMFPYPSGAGLHVGHP GYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  62   RMKRMQGYDVLHPIGWDAFGLPAEQYALKTGNDPREFTDKNIIIFRNQLKKLGFSYDYNK  121
            R KR QG +VLHP+GWDAFGLPAEQYA+ TGNDP EFT  NI  F+ Q++ LGFSYD ++
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  122  EVNTSHPNYYKITQWIFQQLYKKGLAEVKEVNVNWCEELGTVLANEEVILSNGKMVSDIG  181
            EVNT++PNYYK TQWIF +LY KGLA   EV VNW EELGT +ANEEV L++G   S+ G
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEV-LPDG--TSERG  180

Query  182  GFDVIKKPMKQWVLKITQYADRLLDGLENLNWPNSVKELQKNWIGKSEGVLIKFKIKESN  241
            G+ V++KPM+QW+LKIT YA+RLL++LE+++WP+S+K++Q+NWIGKS G  + FK+K+++
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  242  EEIEVFTTRPDTIFGVSYIVLAPENEKVLKICSNNFQNEIENYIQNTKTKTDVERQDDSK  301
             ++ VFTTRPDT+FG +Y VLAPE+  V  I +++  + + +Y +++  K+D+ R D +K
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  302  EKTGLYLGCHAINPITNEEVPIWISDYVLNDYATGAVMAVPAHDERDWKFATKYNLSIKF  361
            EKTG+  G  AINP+   E+P+WI+DYVL  Y+TGA+MAVPAHDERDW FA ++NL I  
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  362  VLETKD-KSKAFVGESEHINSDFLNGLDRKNAIKLVIDKLEKENNGKKQINYKLRDWLFS  420
            VLE  +    AF  ++ HINSDFL+GLD+ +AI  +++ LE E  G+ ++ Y+LRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  421  RQRFYGEPFPVIFLDNGDIALIDEKDLPLMLPKTDYIKPSGTGESPLANIKEWVNI-KYN  479
            RQR+ GEP+P+I  ++G  + + E +LPL+LP T  I+PSGTGESPLAN+ +W+++ + +
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  480  GLNAKRETNTMPQWAGSCWYYLAYILTTSPNNLIDITSEEAMQLFKKWLPVDLYIGGQEH  539
            G++++RETNTMPQWAGS WYYL YI   + ++L D       +L+K+WLPVD+Y+GG EH
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADE------ELLKQWLPVDIYVGGAEH  534

Query  540  AVLHLLYARFWHQVLFDLNVVPTPEPFQKLINQGMIL-------------TDKGE-----  581
            AVLHLLYARFWH+VL+DL VVPT EPFQKL+NQGMIL             TDK E     
Sbjct  535  AVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGS  594

Query  582  ---------------KMSKSKGNVINPDEIIESHGADTLRLYEVFMGPLEASLPWSFKGL  626
                           KMSKS  NV+NPD+++E  GADTLR+YE+FMGPL+AS++WS  GL
Sbjct  595  FFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGL  654

Query  627  DGSRKWLDRVYRLIEDIKLTDENNGNLDFIYNDVVKKTTQMIEDCKFNTAVSQLMVFINA  686
            +GSRK LDRVYRLI    +T+EN+G LD +YN+ VK  T+ +++ KFNTA++QLMVF+NA
Sbjct  655  EGSRKFLDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNA  714

Query  687  VYKENSAIYKPYIFNFVKMLSLYAPHLAEELWSMLGNKT-SVCLESWPVFDETKLLLSNV  745
              KE+  ++  Y   FV++++ +APHL+EELW  L     S+   +WP +DE+KL+ ++V
Sbjct  715  ANKEDK-LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDV  773

Query  746  VIAVQINGKLKSTFEVEKGTSIEELIKLAKNILNVKETIHGKTIIKEIAVLDKIVNIVIK  805
             I VQI+GK+K+ + V K+ S EEL  +A    +V+  I GK IIK IAV +K+VNIVIK
Sbjct  774  EIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

427) Spiaf_2640 in NC_017098


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  768 bits (2906),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 472/855 (56%), Positives = 617/855 (73%), Gaps = 56/855 (6%)

Query  1    MSAYPFKEIEPKWQQYWLQNKTFKAKEDPSFPPEKRRYVLDMFPYPSAAGLHVGHPEGYT  60
            M+ Y    IEPKWQ +W +N TFK+  D+S P   + Y LDMFPYPS+AGLHVGHPEGYT
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKP---KFYALDMFPYPSGAGLHVGHPEGYT  57

Query  61   ATDIYCRFLRMQGYNVLHPMGFDSFGLAAETYAIQNGTHPRTSTEQNIDRFREQIRSLGF  120
            ATDI  RF R QG NVLHPMG D+FGL+AE YA++ G +P   T +NI  F+ QI +LGF
Sbjct  58   ATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGF  117

Query  121  SYDWDREVSTHKPDYYRWTQWIFLKLYERGLAYMAEIPMWYCEALGTVLANEEVITTPDG  180
            SYDWDREV+T  P+YY+WTQWIF KLYE+GLAY AE+P+   E LGT +ANEEV+  PDG
Sbjct  118  SYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVL--PDG  175

Query  181  PRSERGNHPVERRPLRQWMLRITAYADRLLEGLDDLDWPESIKAMQRNWIGRSEGANVRF  240
              SERG  PV R+P+RQWML+ITAYA+RLLE+L+++DWPESIK MQRNWIG+S GANV F
Sbjct  176  T-SERGGYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTF  234

Query  241  QLVDTAAADTQDDIEVFTTRPDTLFGATYMVLAPEHPLVDRITTTEQRAQVDRYIELART  300
            ++      DT+ D+ VFTTRPDTLFGATY VLAPEH+LVD ITT++Q   V  Y   A  
Sbjct  235  KV-----KDTDKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASL  289

Query  301  KSDLERTDLAKEKTGVFTGAYAVNPVNGAHIPIWISDYILLSYGTGAIMAVPAHDTRDFE  360
            KSDL RTDLAKEKTGV TG+YA+NPVNG ++P+WI+DY+L SYGTGAIMAVPAHD RD E
Sbjct  290  KSDLARTDLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWE  349

Query  361  FARTFDLPItpvvapadggaavtdgSEMTEAFTDEGIAINSGQFNGMPTAEFKQAITAWL  420
            FA+ F+L I PV+  ++             AFT++G+ INS+ ++G+  A     +  WL
Sbjct  350  FAKQFNLDIIPVLEGGNVE---------EAAFTEDGLHINSDFLDGLDKASAIAKMVEWL  400

Query  421  AEQGLGSHAVNYKLRDWIFSRQRYWGEPIPLVHCEDGSIQPLPEDQLPLTLPEVETYKPT  480
              +G+G++ V Y+LRDW+FSRQRYWGEPIP++H EDG+  ++PE +LPL LP     +P+
Sbjct  401  EAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPS  460

Query  481  GTGESPLANVAEWVNTGCPAEPGKQGTRETNTMPQWAGSCWYFLRYIDPHNTEQLVDPEK  540
            GTGESPLANV++W++     E G +G RETNTMPQWAGS WY+LRYIDPHNTE+L D E 
Sbjct  461  GTGESPLANVTDWLE--VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEEL  518

Query  541  AAYWMPVDLYVGGAEHAVLHLLYARFWHKVLFDLGVVHTEEPFTRLVNQGMILG------  594
               W+PVD+YVGGAEHAVLHLLYARFWHKVL+DLGVV T EPF +L NQGMILG      
Sbjct  519  LKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDS  578

Query  595  ---------------------------EGGVKMSKSLGNVINPDDIVAEFGADAMRVYEM  627
                                       ++  KMSKSL NV+NPDD+V ++GAD++RVYEM
Sbjct  579  RGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEM  638

Query  628  FMGPLRQSKPWNTQGLSGVYRFLDRVWKLGQRSLSDAQPPEALQRTLHKTIRKVARDTEN  687
            FMGPL  S +W+ +GL G  +FLDRV +L        + + AL++  + T++ V+ + ++
Sbjct  639  FMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQ  698

Query  688  LDFNTAISQMMIFINEISKENTHYRQLWEPFVLVLAPYAPHLAEELWQQL-GHTETLAYE  746
            + FNTAI+Q+M+F+N  +KE+  + +    FV ++AP+APHL+EELWQ L +  E+++Y 
Sbjct  699  MKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYV  758

Query  747  SFPIWDEELCRDNEVEVVFQVNGKVRDKAVLPADSDKQALEAAARASEKIQGYLDGKTVV  806
            + P  DE    +N+VE+V Q++GKV+ K V++ D  ++ L+  A A+EK+Q+ + GK ++
Sbjct  759  PWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDII  818

Query  807  KVIAVPRKLVNFVIR  821
            KVIAVP KLVN+VI+
Sbjct  819  KVIAVPNKLVNIVIK  833

428) leuS in NC_011026


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  767 bits (2903),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 462/844 (55%), Positives = 614/844 (73%), Gaps = 55/844 (6%)

Query  3    YDFTEIEKKWQAYWEQHQTFKATEEPNKPKYYVLDMFPYPSGSGLHVGHLEGYTASDITA  62
            YD T IE KWQA+W +++TFK+  +++KPK+Y LDMFPYPSG+GLHVGH EGYTA+DI +
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRLKGFSVLHPMGWDAFGLPAEQYAIKTGTHPRLTTETNVANFKSTLQRMGFSYDWSR  122
            R+KR +G +VLHPMGWDAFGLPAEQYA+ TG +P   T  N+ANFK  ++ +GFSYDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EINTTDPGYVKWTQWIFLKLYEKGLAYVDDVPVNWCEELKVVLANEEV---DEKVNDGYT  179
            E+NTTDP Y KWTQWIF KLYEKGLAY  +VPVNW EEL   +ANEEV   +    +GY 
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  180  VVRRPLRQWMLKITAYAERLLTDLDEVDWPESVKEMQRNWIGKSVGAELDFYLAGTDEKF  239
            VVR+P+RQWMLKITAYAERLL DL+EVDWPES+K+MQRNWIGKS GA++ F + +TD  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  240  RIFTTRPDTVFGATYMVLSPEHPLLDKITTDEHKSAVAAYREEAERKSDLERTGLQKEKT  299
             +FTTRPDT+FGATY VL+PEH+L+D ITT ++  AVA Y+ +A  KSDL RT+L KEKT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  300  GVFTGSYALNPATGKEIPIWTSDFVLMGYGTGAIMSVPAHDERDWEFAKKFGIPIVEVIK  359
            GV TGSYA+NP  GKE+P+W +D+VL +YGTGAIM+VPAHDERDWEFAK+F + I+ V+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  360  SPHSVQEAVFAGKDSVCTNSENAEISINGLAYEEAFEKITDWFEKKGLGQRKVNYKLRDW  419
            + + V+EA F+  D++  NS+     ++GL    A+ K+ +W+E  G+G+ +V Y+LRDW
Sbjct  364  GGN-VEEAAFTE-DGLHINSD----FLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDW  417

Query  420  LFSRQRYWGEPIPIKHYEDGAERA--ETELPLNLPEVSAYQPSGTGESPLANIAEWLYGE  477
            LFSRQRYWGEPIPI H EDG+  A  E+ELPL LP     +PSGTGESPLAN+++WL   
Sbjct  418  LFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT  477

Query  478  DEHG-KFRRETNTMPQWAGSCWYYLRFIDPDNPNEAVSPEKEKYWMNVDLYIGGAEHAVL  536
             E+G K RRETNTMPQWAGS WYYLR+IDP+N +     E  K W+ VD+Y+GGAEHAVL
Sbjct  478  REDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVL  537

Query  537  HLLYARFWHKVLYDVGVVSTKEPFRKLFNQGMILG-------------------------  571
            HLLYARFWHKVLYD+GVV+TKEPF+KLFNQGMILG                         
Sbjct  538  HLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFH  597

Query  572  --------EDNEKMSKSRGNVITADSVMSGYGADAVRLYEMFLGPLEQVKPWSTNGIEGI  623
                    +   KMSKS  NV+ +D V+  YGAD++R+YEMF+GPL+   +WS +G+EG 
Sbjct  598  VETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGS  657

Query  624  SRFLGKVWRLVYPNEADGTVQVTDDAPSETVLRRM-HKTIKKVGEDTETLKFNTAISEMM  682
             +FL++V RL+       T ++T++ ++   L ++ + T+K V E+ + +KFNTAI+++M
Sbjct  658  RKFLDRVYRLI------TTKEITEENSG--ALDKVYNETVKAVTEQVDQMKFNTAIAQLM  709

Query  683  IYVNELQKEKCRSRTAIENLLLMLSPFAPHICEELWQAL-GHEESITFAKFPEYDATLAK  741
            ++VN  +KE          ++ +++PFAPH+ EELWQAL +  ESI++   P YD +   
Sbjct  710  VFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLV  769

Query  742  DDVVTIAVQVNGKLRGTFDAAAGLSKDDMIAEAMKVESVIKFTEGKEIVKQIAVPNKLVN  801
            ++ V I VQ++GK+++ +  A +LS++++   A+  E V     GK+I+K IAVPNKLVN
Sbjct  770  ENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVN  829

Query  802  LVVK  805
            +V+K
Sbjct  830  IVIK  833

429) Rmar_0671 in NC_013501


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  766 bits (2897),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 491/907 (55%), Positives = 648/907 (72%), Gaps = 77/907 (8%)

Query  1    MAGYPFKETEKKWQRYWDEHKIFRTAGPKEPGFDPNKPKYYVLDMFPYPSGAGLHVGHPE  60
            M+ Y     E KWQ +W ++  F+T+       D++KPK+Y LDMFPYPSGAGLHVGHPE
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGT------DASKPKFYALDMFPYPSGAGLHVGHPE  54

Query  61   GYTATDIMARYRRMKGYNVLHPMGWDAFGLPAEQYAIETNTHPRITTERNITRFRSQLKS  120
            GYTATDI++R++R +G NVLHPMGWDAFGLPAEQYA++T  +P   T  NI+ F+ Q+++
Sbjct  55   GYTATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINA  114

Query  121  LGFSYDWDREINTTDPRYYKWTQWIFLQLYKMGLAYEAEVPVNWCPALGTVLANEEVI-D  179
            LGFSYDWDRE+NTTDP YYKWTQWIF +LY  GLAYEAEVPVNW   LGT +ANEEV+ D
Sbjct  115  LGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPD  174

Query  180  GKSERGGYPVYRRPMRQWMLRITAYADRlledlelldWPESIKEMQRNWIGRSEGAEIEF  239
            G SERGGYPV R+PMRQWML+ITAYA+RLLEDLE +DWPESIK+MQRNWIG+S GA++ F
Sbjct  175  GTSERGGYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTF  234

Query  240  PVVGLDARIRVFTTRPDTLFGATYMVLAPEHPLVDQITTPEHRAEVEAYRRQAQQKSDLE  299
             V + D  + VFTTRPDTLFGATY VLAPEH+LVD ITT+++   V  Y+RQA  KSDL 
Sbjct  235  KVKDTDKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLA  294

Query  300  RTELAREKTGVFTGGYAINPATGQQIPIWIADYVLGHYGTGAIMAVPGHDQRDWEFARKY  359
            RT+LA+EKTGV TG+YAINP  G+++P+WIADYVL+ YGTGAIMAVP+HD+RDWEFA+++
Sbjct  295  RTDLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQF  354

Query  360  NLPIVEVVQGGNLEEGAYEGDGPHVNSANDEVSLNGLHNEEAKRVIVEWLERKGLGKRSV  419
            NL I+ V++GGN+EE+A+  DG H+NS      L+GL++  A   +VEWLE  G+G+ +V
Sbjct  355  NLDIIPVLEGGNVEEAAFTEDGLHINSD----FLDGLDKASAIAKMVEWLEAEGVGNENV  410

Query  420  QYRLRDWLFSRQRYWGEPFPIVHEVDEEGRRTGRTYPLDESELPVELPDLEDFRPQPASD  479
             YRLRDWLFSRQRYWGEP+PI+H      +  G + ++ ESELP+ LP   D+RP  +++
Sbjct  411  TYRLRDWLFSRQRYWGEPIPIIH------WEDGTSTAVPESELPLVLPVTKDIRPSGTGE  464

Query  480  PDAEPQPPLARAVDWVRVKGWVTPEGTVRLLKPGVEPPPGVEIKNFHRETNTMPQWAGSC  539
            +      PLA   DW+ V    T E+ V+                 +RETNTMPQWAGS 
Sbjct  465  S------PLANVTDWLEV----TREDGVKG----------------RRETNTMPQWAGSS  498

Query  540  WYYLRYIDPHNDERFVDPEKERYWMPVDLYVGGAEHAVLHLLYARFWHKVLYDLGLVSTP  599
            WYYLRYIDPHN E++ D E  + W+PVD+YVGGAEHAVLHLLYARFWHKVLYDLG+V+T 
Sbjct  499  WYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTK  558

Query  600  EPFMKLVNQGLILGEMEYTAFRDAEGRWVSAEFVDDGIDVRTGQKLEAVKLKEDEVEKQG  659
            EPF KL NQG+ILG    T++RD+ G  V+++ V+                      ++G
Sbjct  559  EPFQKLFNQGMILG----TSYRDSRGALVATDKVEK---------------------RDG  593

Query  660  DFFVLKAHPEIRVEARAYKMSKSRGNVVNPDDVIEQYGADSLRLYEMFMGPLEQVKPWSM  719
             FF + +  E+  E  + KMSKS  NVVNPDDV+EQYGAD+LR+YEMFMGPL+   +WS 
Sbjct  594  SFFHVETGEEL--EQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSE  651

Query  720  RGVEGVHRFLNRVWRLYVNDADGSLRVTDAEPTREQlrvlhrtlrrvtDDIEAMRFNTAI  779
             G+EG ++FL+RV RL         +    E +    +V + T++ VT++++ M+FNTAI
Sbjct  652  EGLEGSRKFLDRVYRLITT------KEITEENSGALDKVYNETVKAVTEQVDQMKFNTAI  705

Query  780  AAMMEFVNEANRWDTFPRAVAEPFVLMLSPFAPHIAEELWERL-GHTESLAYEPWPEVNE  838
            A +M FVN AN+ D +    A  FV +++PFAPH++EELW+ L +  ES++Y PWP  +E
Sbjct  706  AQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDE  765

Query  839  EYLKVDEVEIAVQVNGKVRATVRIPAEADQETALAIARQHENVARYIDGKTIRRAIYVPG  898
              L  ++VEI VQ++GKV+A + ++ +  +E    +A  +E+V   I GK I + I VP 
Sbjct  766  SKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPN  825

Query  899  RIINFVV  905
            +++N+V+
Sbjct  826  KLVNIVI  832

430) Rhom172_2212 in NC_015966


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  766 bits (2900),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 494/907 (55%), Positives = 652/907 (72%), Gaps = 77/907 (8%)

Query  1    MAGYPFKEIEKKWQRYWDEHKTFRTAGPKEPGFDPNKPKYYVLDMFPYPSGAGLHVGHPE  60
            M+ Y    IE KWQ +W ++ TF+T+       D++KPK+Y LDMFPYPSGAGLHVGHPE
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGT------DASKPKFYALDMFPYPSGAGLHVGHPE  54

Query  61   GYTATDIMARYRRMKGYNVLHPMGWDAFGLPAEQYAIETNTHPRITTERNIARFRAQLKS  120
            GYTATDI++R++R +G NVLHPMGWDAFGLPAEQYA++T  +P   T  NIA F+ Q+++
Sbjct  55   GYTATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINA  114

Query  121  LGFSYDWDREINTTDPRYYKWTQWIFLQLYKMGLAYEAEVPVNWCPALGTVLANEEVI-D  179
            LGFSYDWDRE+NTTDP YYKWTQWIF +LY  GLAYEAEVPVNW   LGT +ANEEV+ D
Sbjct  115  LGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPD  174

Query  180  GKSERGGYPVYRRPMRQWMLRITAYADRlledlelldWPESIKEMQRNWIGRSEGAEIEF  239
            G SERGGYPV R+PMRQWML+ITAYA+RLLEDLE +DWPESIK+MQRNWIG+S GA++ F
Sbjct  175  GTSERGGYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTF  234

Query  240  PVVGLDARIRVFTTRPDTLFGATYMVLAPEHPLVDQITTPEHRAEVEAYRRQAQQKSDLE  299
             V + D  + VFTTRPDTLFGATY VLAPEH+LVD ITT+++   V  Y+RQA  KSDL 
Sbjct  235  KVKDTDKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLA  294

Query  300  RTELAREKTGVFTGGYAINPATGQQIPIWIADYVLGHYGTGAIMAVPGHDQRDWEFARKH  359
            RT+LA+EKTGV TG+YAINP  G+++P+WIADYVL+ YGTGAIMAVP+HD+RDWEFA++ 
Sbjct  295  RTDLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQF  354

Query  360  NLPIVEVVQGGNLEEGAYEGDGPHVNSANDEVSLNGLHNEEAKRVIVEWLERKGLGKRSV  419
            NL I+ V++GGN+EE+A+  DG H+NS      L+GL++  A   +VEWLE  G+G+ +V
Sbjct  355  NLDIIPVLEGGNVEEAAFTEDGLHINSD----FLDGLDKASAIAKMVEWLEAEGVGNENV  410

Query  420  QYRLRDWLFSRQRYWGEPFPIVHEVDEEGRRTGRTYPLDESELPVELPDLEDFRpqpapd  479
             YRLRDWLFSRQRYWGEP+PI+H      +  G + ++ ESELP+ LP   D+R      
Sbjct  411  TYRLRDWLFSRQRYWGEPIPIIH------WEDGTSTAVPESELPLVLPVTKDIR------  458

Query  480  pdaepqppLARAVDWVRVRGWVTPEGTVQLLKPGVEPPPGVEIKNFHRETNTMPQWAGSC  539
            P +  ++PLA   DW+     VT E+ V+                 +RETNTMPQWAGS 
Sbjct  459  PSGTGESPLANVTDWLE----VTREDGVKG----------------RRETNTMPQWAGSS  498

Query  540  WYYLRYIDPHNDERFVDPEKERYWMPVDLYVGGAEHAVLHLLYARFWHKVLYDLGLVSTP  599
            WYYLRYIDPHN E++ D E  + W+PVD+YVGGAEHAVLHLLYARFWHKVLYDLG+V+T 
Sbjct  499  WYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTK  558

Query  600  EPFMKLVNQGLILGEMEYTAFRDAEGRWVSAEFVDDGIDVRTGQKLEAVKLKEDEVEKQG  659
            EPF KL NQG+ILG    T++RD+ G  V+++ V+                      ++G
Sbjct  559  EPFQKLFNQGMILG----TSYRDSRGALVATDKVEK---------------------RDG  593

Query  660  DFFVLKAHPEIRVEARAYKMSKSRGNVVNPDDVVEQYGADSLRLYEMFMGPLEQVKPWST  719
             FF + +  E+  E  + KMSKS  NVVNPDDVVEQYGAD+LR+YEMFMGPL+   +WS 
Sbjct  594  SFFHVETGEEL--EQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSE  651

Query  720  RGVEGVHRFLNRVWRLYVNDADGSLRVTDAEPTREQLRVLHQTLRRVTDDIEAMRFNTAI  779
             G+EG ++FL+RV RL          +T+ ++   + +V ++T++ VT++++ M+FNTAI
Sbjct  652  EGLEGSRKFLDRVYRLITTKE-----ITEENSGALD-KVYNETVKAVTEQVDQMKFNTAI  705

Query  780  AAMMEFVNEANRWETFPRTVAEPFVLMLSPFAPHIAEELWERL-GHTESLAYEPWPEVNE  838
            A +M FVN AN+ + +    A  FV +++PFAPH++EELW+ L +  ES++Y PWP  +E
Sbjct  706  AQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDE  765

Query  839  EYLKVDEVEIAVQVNGKVRATVRIPAEADQETALAIARQHENVARYIDGKPIRRAIYVPG  898
              L  ++VEI VQ++GKV+A + ++ +  +E    +A  +E+V   I GK I + I VP 
Sbjct  766  SKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPN  825

Query  899  RIINFVV  905
            +++N+V+
Sbjct  826  KLVNIVI  832

431) leuS in NC_002932


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  765 bits (2894),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 455/842 (55%), Positives = 613/842 (73%), Gaps = 52/842 (6%)

Query  3    YDFSALEKKWQSRWADEQTFASSADQEKPKYYVLDMFPYPSGSGLHVGHLEGYTATDIMA  62
            YD +A+E KWQ+ WAD++TF +++D  KPK+Y LDMFPYPSG+GLHVGH EGYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRCQGHNVLHPMGWDAFGLPAEQFAIKTGTHPRLTTEKNVASFRETLKSMGFSYDWSR  122
            R+KR QGHNVLHPMGWDAFGLPAEQ+A+ TG +P   T  N+A+F+  ++++GFSYDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EINTTDPNYFKWTQWIFLKLYEKGLAYISEVDVNWCEELKVVLANEEV---DEKIADGYT  179
            E+NTTDPNY+KWTQWIF KLYEKGLAY +EV VNW EEL   +ANEEV   +    +GY 
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  180  VVRRPLRQWVLKITAYAERLLKDLDEVDWPENVKQMQRNWIGRSEGMEIDFELRCHRTNL  239
            VVR+P+RQW+LKITAYAERLL DL+EVDWPE++K+MQRNWIG+S G ++ F ++    ++
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  240  RVYTTRPDTLFGATYLVISPEHPMAEKLAIAQQLVAVKKYIEQAKLKTELERTGLQKEKT  299
             V+TTRPDTLFGATY V++PEH++ + ++ ++Q  AV  Y  QA LK++L RT+L KEKT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  300  GVFTGSYAINPANGEALPVWISDFVLTSYGTGAIMSVPAHDSRDWEFAKKFGLPIREVIK  359
            GV TGSYAINP NG  +PVWI+D+VL+SYGTGAIM+VPAHD RDWEFAK+F L I  V+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  360  SPHDVQERVFDGKESVCVNSANDEISINGLDFKTAFDRMAAWLESKGKGKRKVNYKLRDW  419
            + + V+E  F   +++ +NS      ++GLD  +A+ +M  WLE+ G G+ +V Y+LRDW
Sbjct  364  GGN-VEEAAF-TEDGLHINSD----FLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDW  417

Query  420  VFSRQRYWGEPIPIKHYEDGTMR--PETNLPLTLPEVEAYQPTSTGESPLANIESWLYGE  477
            +FSRQRYWGEPIPI H EDGT    PE++LPL LP     +P++TGESPLAN+  WL   
Sbjct  418  LFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT  477

Query  478  DEHG-KFRRETNTMPQWAGSCWYYLRFIDPQNSDALVDPSLEQYWMNVDLYIGGAEHAVL  536
             E+G K RRETNTMPQWAGS WYYLR+IDP+N++ L D  L + W+ VD+Y+GGAEHAVL
Sbjct  478  REDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVL  537

Query  537  HLLYSRFWHKVLYDLGVVSTKEPFQRLFNQGMILG-------------------------  571
            HLLY+RFWHKVLYDLGVV+TKEPFQ+LFNQGMILG                         
Sbjct  538  HLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFH  597

Query  572  --------EDNEKMSKSRGNVIPADHVLSTYGADALRLYEMFLGPLDQVKPWNTHGIEGI  623
                    +   KMSKS  NV+ +D+V+  YGAD+LR+YEMF+GPLD   +W+ +G+EG 
Sbjct  598  VETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGS  657

Query  624  SRFLNKVWRLVWDENTETQKTTEDKPSEAILKRMHKAIKKVTEDTEQLKFNTAISEMMVL  683
             +FL++V RL+      T K   +  S A+ K  + ++K VTE+ +Q+KFNTAI+++MV+
Sbjct  658  RKFLDRVYRLI------TTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVF  711

Query  684  VNELHKAGCYSRETTETLLVLLSPFAPHITEELWQAL-GHAESISGAVWPVFDAKLATDD  742
            VN  +K +    + +  ++ L++PFAPH+ EELWQAL + +ESIS   WP +D     ++
Sbjct  712  VNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVEN  771

Query  743  VLTIAVQVNGKLRGTFEAPAGCTKEEMIESAKKVESVAKFLDGQQIVKEIAVPGKLVNFA  802
             + I VQ++GK+++ +  + + ++EE+ E A   E V   + G++I+K IAVP KLVN+ 
Sbjct  772  DVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIV  831

Query  803  VK  804
            +K
Sbjct  832  IK  833

432) leuS in NC_011027


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  760 bits (2875),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 454/842 (54%), Positives = 609/842 (73%), Gaps = 52/842 (6%)

Query  3    YDFSALEKKWQARWADEQTFASSADQDKPKYYVLDMFPYPSGSGLHVGHLEGYTATDIMA  62
            YD +A+E KWQA WAD++TF +++D  KPK+Y LDMFPYPSG+GLHVGH EGYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRCQGHNVLHPMGWDAFGLPAEQFAIKTGTHPRLTTEKNVASFRETLKSMGFSYDWSR  122
            R+KR QGHNVLHPMGWDAFGLPAEQ+A+ TG +P   T  N+A+F+  ++++GFSYDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVNTTDPNYFKWTQWIFLKLYEKGLAYISEVDVNWCEELKVVLANEEV---DEKIADGYT  179
            EVNTTDPNY+KWTQWIF KLYEKGLAY +EV VNW EEL   +ANEEV   +    +GY 
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  180  VVRRPLRQWVLKITAYAERLLEDLDEVDWPENVKQMQRNWIGRSEGVEIDFELRCHRTNL  239
            VVR+P+RQW+LKITAYAERLLEDL+EVDWPE++K+MQRNWIG+S G ++ F ++    ++
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  240  RVYTTRPDTLFGATYLVISPEHPMAEKLAIAQQLVEVKKYIEQAKLKTELERTGLQKEKT  299
             V+TTRPDTLFGATY V++PEH++ + ++ ++Q   V  Y  QA LK++L RT+L KEKT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  300  GVFTGSYAINPANGEALPVWISDFVLTSYGTGAIMSVPAHDSRDWEFAKKFGLPIREVIK  359
            GV TGSYAINP NG  +PVWI+D+VL+SYGTGAIM+VPAHD RDWEFAK+F L I  V+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  360  SPHDVQEEVFDGKESVCVNSANDEISIDGLDFKTAFDRMATWLESKGKGKRKVNYKLRDW  419
            + + V+E  F   +++ +NS      +DGLD  +A+ +M  WLE+ G G+ +V Y+LRDW
Sbjct  364  GGN-VEEAAF-TEDGLHINSD----FLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDW  417

Query  420  VFSRQRYWGEPIPIKHYEDGTMR--PETNLPLTLPEVEAYHPTSTGESPLANIESWLYGE  477
            +FSRQRYWGEPIPI H EDGT    PE++LPL LP     +P++TGESPLAN+  WL   
Sbjct  418  LFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT  477

Query  478  DEHG-KFRRETNTMPQWAGSCWYYLRFIDPQNGNALVDPSREQYWMNVDLYIGGAEHAVL  536
             E+G K RRETNTMPQWAGS WYYLR+IDP+N + L D    + W+ VD+Y+GGAEHAVL
Sbjct  478  REDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVL  537

Query  537  HLLYSRFWHKVLYDLGVVSTKEPFQRLFNQGMILG-------------------------  571
            HLLY+RFWHKVLYDLGVV+TKEPFQ+LFNQGMILG                         
Sbjct  538  HLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFH  597

Query  572  --------EDNEKMSKSRGNVIPADHVLSTYGADAVRLYEMFLGPLEQVKPWNTHGIEGI  623
                    +   KMSKS  NV+ +D+V+  YGAD++R+YEMF+GPL+   +W+ +G+EG 
Sbjct  598  VETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGS  657

Query  624  SRFLNKVWRLVWDENTETQKTTDDKPSEAVLKRMHKAIKKVTEDTEQLKFNTAISEMMVL  683
             +FL++V RL+      T K   +  S A+ K  + ++K VTE+ +Q+KFNTAI+++MV+
Sbjct  658  RKFLDRVYRLI------TTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVF  711

Query  684  VNELTKTGCYSRETTETLLVLLSPFAPHITEELWQTL-GHTESISGAVWPVFDAKLATDD  742
            VN   K +    + +  ++ L++PFAPH+ EELWQ+L +  ESIS   WP +D     ++
Sbjct  712  VNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVEN  771

Query  743  VLTIAVQVNGKLRGTFEAPAGYAKEDMIESAKKVESVAKFLEGQQIIKEIAVPGKLVNFA  802
             + I VQ++GK+++ +  + + ++E++ E A   E V   + G++IIK IAVP KLVN+ 
Sbjct  772  DVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIV  831

Query  803  VK  804
            +K
Sbjct  832  IK  833

433) Spica_2714 in NC_015732


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  758 bits (2868),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 467/854 (55%), Positives = 606/854 (71%), Gaps = 56/854 (6%)

Query  1    MAKYPFDTIEPKWQKYWEEHKTFKAVEDPAFPKEKRQYVLDMFPYPSAQGLHVGHPEGYT  60
            M+ Y   +IEPKWQ +W ++ TFK+  D++ PK    Y LDMFPYPS+ GLHVGHPEGYT
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPK---FYALDMFPYPSGAGLHVGHPEGYT  57

Query  61   ATDIYCRYLRMNGFNVLHPMGFDAFGLPAENYAIKTGTHPATTTRANIDKFRTQIKALGF  120
            ATDI  R+ R +G NVLHPMG DAFGLPAE+YA+ TG +PA  T  NI +F+ QI+ALGF
Sbjct  58   ATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGF  117

Query  121  SYDWDREVSTCEADYYKWTQWIFLKLFEKGLAYEAETPINWCPSCKTGLANEEV-KDGAC  179
            SYDWDREV+T +++YYKWTQWIF KL+EKGLAYEAE P+NW     T++ANEEV  DG+ 
Sbjct  118  SYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTS  177

Query  180  DRCGTKVTRKRIRQWILKITAYAERlledldlldWPEPVKLMQRNWIGKSEGANVIFKID  239
            +R G  V RK +RQW+LKITAYAERLLEDL+ +DWPE++K MQRNWIGKS GANV FK+ 
Sbjct  178  ERGGYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVK  237

Query  240  GHDAELEIYTTRPDTLFGATYMVLAPEHPLVPKITTAEQKAAVEAYLDAAAKKSDLERTD  299
            + D ++ ++TTRPDTLFGATY VLAPEH+LV  ITT++Q  AV  Y   A+ KSDL RTD
Sbjct  238  DTDKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTD  297

Query  300  LAKEKTGVFSGAYALNPVNGKKIPIWIADYVLISYGTGAIMAVPAHDERDWDFAKAFNLP  359
            LAKEKTGV +G+YA+NPVNGK +P+WIADYVL SYGTGAIMAVPAHDERDW+FAK FNL 
Sbjct  298  LAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLD  357

Query  360  IIQVVAGEPPAIGKDYSQTPETCTTADGWAVNSGPFDGTPTAEFKQKIIGWLEEKGIGKR  419
            II V+ G         ++  E+  T DG  +NS+ +DG   A    K++ WLE  G+G+ 
Sbjct  358  IIPVLEG---------GNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNE  408

Query  420  AVNYKLRDWIFSRQRYWGEPIPIVHCESCGIVPLPEDQLPLTLPDVQSYAPTGTGESPLA  479
             V Y+LRDW+FSRQRYWGEPIPI+H E     ++PE +LPL LP  +   P+GTGESPLA
Sbjct  409  NVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLA  468

Query  480  GITDWVNTTCPKCGGKAKRETNTMPQWAGSCWYYLRYLDPHNDKEFASKKAIEYWMPVDL  539
             +TDW++ T    G K++RETNTMPQWAGS WYYLRY+DPHN   +A    +  W+PVD+
Sbjct  469  NVTDWLEVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDI  527

Query  540  YVGGTEHAVLHLLYSRFWHKVLYDLGLVNSKEPFQRLVNQGMILG---------------  584
            YVGG+EHAVLHLLY+RFWHKVLYDLG+V +KEPFQ+L NQGMILG               
Sbjct  528  YVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDK  587

Query  585  ------------------EDGQKMSKSRGNVINPDDIIRDYGADSMRVYEMFMGPLEVSK  626
                              +   KMSKS  NV+NPDD++ +YGAD++RVYEMFMGPL+ S 
Sbjct  588  VEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASI  647

Query  627  PWATAGLVGVSRFLERLWALGEKPLADTPEAAGISSDQKTELLRILHKTIKKVTDDTSTL  686
            +W+  GL G  +FL+R+  L          +  I+ ++   L ++ + T+K VT++   +
Sbjct  648  AWSEEGLEGSRKFLDRVYRL--------ITTKEITEENSGALDKVYNETVKAVTEQVDQM  699

Query  687  NFNTAISAMMVYSSELAKLEKLPRPFWEPLVQMVSPYAPHLAEELWEKL-GYKESISKSQ  745
            +FNTAI+ +MV+ +   K +KL   +   +VQ+++P+APHL+EELW+ L +  ESIS   
Sbjct  700  KFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVP  759

Query  746  WPQYDASLAADNEVTIVVQVNGKIRDKFTAPIGISKAELEKTALNLPGIQKWLEGLTIAK  805
            WP YD S   +N+V IVVQ++GK++ K+  + ++S+ EL+  AL    +Q  + G  I K
Sbjct  760  WPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIK  819

Query  806  VISVPDKLVNIVVK  819
            VI+VP+KLVNIV+K
Sbjct  820  VIAVPNKLVNIVIK  833

434) leuS in NC_007677


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  755 bits (2856),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 477/863 (56%), Positives = 633/863 (74%), Gaps = 37/863 (4%)

Query  3    YPFHDIETKWQQYWEEHQTFRTPDEVPDDQEEFYVLDMFPYPSGSGLHVGHPEGYTATDI  62
            Y    IE KWQ +W +++TF+T  + +  +  FY LDMFPYPSG+GLHVGHPEGYTATDI
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDAS--KPKFYALDMFPYPSGAGLHVGHPEGYTATDI  61

Query  63   VARYKRKQGFNVLHPMGWDAFGLPAEQYALKTNTHPRETTEKNIAQFKRQLKRLGFSYDW  122
            ++R+KR QG NVLHPMGWDAFGLPAEQYA+ T  +P E T  NIA+FKRQ++ LGFSYDW
Sbjct  62   LSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDW  121

Query  123  QREINTTDPDYYKWTQWIFLQLYEKGLAYQSEEPVWWCEELGTVLANEEVI-DGKSERGG  181
            +RE+NTTDP+YYKWTQWIF +LYEKGLAY++E PV W EELGT +ANEEV+ DG SERGG
Sbjct  122  DREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGG  181

Query  182  YPCERVPMRQWVLKITEYADRLLEGLEDLDWPESTKEMQRNWIGRSEGANVYFDLVGADD  241
            YP  R PMRQW+LKIT YA+RLLE+LE++DWPES K+MQRNWIG+S GANV F + ++D 
Sbjct  182  YPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDK  241

Query  242  ALEVYTTRPDTLFGATYMVLAPEHELLDEITTDEHREDVDEYCRQALRKSERKRQQQG-D  300
             + V+TTRPDTLFGATY VLAPEH L+D ITT ++ E V +Y RQA  KS+  R + + +
Sbjct  242  DFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKE  301

Query  301  KTGVFTGGYAVNPVNGEEIPIWVADYVLVSYGTGAIMAVPAHDERDHAFANKYDLPIREV  360
            KTGV TG+YA+NPVNG E+P+W+ADYVL SYGTGAIMAVPAHDERD  FA++++L I  V
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  361  VEGGDIDEEAYTGDGPHVHSANEAVSLNGLRNEEAKEAITEWLDEEEKGERTVNYQLQDW  420
            +EGG+++E A+T DG H++S      L+GL +  A   + EWL+ E  G+  V Y+L+DW
Sbjct  362  LEGGNVEEAAFTEDGLHINSD----FLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDW  417

Query  421  LFSRQRYWGEPFPIVFTEDGEDKpvpeeelpvtlpdldVFEPSGTPEGPLATIEDWRETT  480
            LFSRQRYWGEP+PI+  EDG   +VPE ELP+ LP    + PSGT E+PLA + DW E T
Sbjct  418  LFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT  477

Query  481  DPETGEPAQRETNTMPQWAGSCWYYLRFIDPDNDEQLVDPEKEEYWMPVDLYVGGSEHAV  540
              E G  ++RETNTMPQWAGS WYYLR+IDP+N E+L D E    W+PVD+YVGG+EHAV
Sbjct  478  -REDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  541  LHLLYARFWHKVLYDAGVVSTKEPFQTLVHQGMILGETEYTAYRDDAGEFVSAEQVDDDA  600
            LHLLYARFWHKVLYD GVV+TKEPFQ L +QGMILG    T+YRD  G +V++++V+   
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILG----TSYRDSRGALVATDKVEKRD  592

Query  601  DLTpvpvddgdvkkdgdvFVLADRPAVRVDARSHKMSKSRGNVINPDDVVDEYGADTLRL  660
            +                 F   +  +  ++  + KMSKS  NV+NPDDVV++YGADTLR+
Sbjct  593  G----------------SFFHVE-TGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRV  635

Query  661  YEMFMGPLEQDKPWSTDDMEGVHRFLNRIWRLVVDADSGGLAVSDEEPDREQLRTLHRTI  720
            YEMFMGPL+   +WS +++EG ++FL+R+ RL+   +     +++E+++  + +  + T+
Sbjct  636  YEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKE-----ITEENSGALD-KVYNETV  689

Query  721  KTVTEDIEARDFNTAIAAMMEFVNAANKWDALPRQVATPFVLLLSPFAPHLAEELWARL-  779
            K+VTE+++   FNTAIA +M FVNAANK D L  + A  FV L++PFAPHL+EELW  L 
Sbjct  690  KAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALT  749

Query  780  GHDQSLAYADWPAYDDELIRREVVEMPVQVDGTVRatievaadaeeadvlataKEAENVA  839
            + ++S++Y  WP+YD+  +  + VE+ VQ+ G V+A + VA D    ++   A   E+V 
Sbjct  750  ASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQ  809

Query  840  RHLDDEDLQREIYVPGQIVNFVT  862
             ++ + D+ + I VP ++VN+V 
Sbjct  810  AEIAGKDIIKVIAVPNKLVNIVI  832

435) leuS in NC_002967


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  753 bits (2850),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 473/859 (56%), Positives = 629/859 (74%), Gaps = 32/859 (3%)

Query  3    YPFSTIEPKWQKYWEENKTFKTVEDKNYPKDKRLYILDMFPYPSGDGLHVGHPEGYTATD  62
            Y  ++IEPKWQ +W +N TFKT  D + PK   +Y LDMFPYPSG GLHVGHPEGYTATD
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPK---FYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  63   IYSRFLRMSGYNVLHPMGFDSFGLPAENYAIKTGIHPLITTRKNMETFRKQIKSIGLSYD  122
            I SRF R  G NVLHPMG D+FGLPAE+YA+ TG +P   T  N+  F++QI+++G+SYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  123  WDREISTSEESYYKWTQWIFLQLFKKGLAYEKEAPINWCPSCLTGLANEEV-KDGKCERC  181
            WDRE++T++ +YYKWTQWIF +L+ KGLAYE E P+NW     T++ANEEV  DG  ER 
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  182  GAQIQRKNLRQWILKITEYAerlledldeldWPESIKIMQKNWIGKSTGAEVDFALVDKD  241
            G  + RK +RQW+LKIT YAERLLEDL+E+DWPESIK MQ+NWIGKSTGA+V F +    
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKV----  236

Query  242  GKETGQKIKVYTTRPDTIFGATYMVLAPEHELVKSITTSNQEKAVAAYIEEAAKKSDLER  301
             K+T++ + V+TTRPDT+FGATY VLAPEH LV +ITTS+Q  AVA Y  +A+ KSDL R
Sbjct  237  -KDTDKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLAR  295

Query  302  TDLAKNKTGVFTGAYAINPLTEQKIPVWISDYILISYGTGAIMAVPAHDERDFEFAAQFN  361
            TDLAK+KTGV TG+YAINP+  + +PVWI+DY+L SYGTGAIMAVPAHDERD EFA QFN
Sbjct  296  TDLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFN  355

Query  362  LPKIKVVAGAEEWESGKRDFSEEPKACTTEDGYSVNSKQFDGLKTEEAKTKITEHLENLG  421
            L  I V+ G+           +   A  TEDG  +NS  +DGL    A +K+ E LE  G
Sbjct  356  LDIIPVLEGG-----------NVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEG  404

Query  422  IAKRAVNYKLRDWIFSRQRYWGEPIPLVHCPSCGIVPLNEHDLPLTLPQVESYAPTGTGE  481
            +++  V Y+LRDW+FSRQRYWGEPIP++H       ++ E +LPL LP      P+GTGE
Sbjct  405  VGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGE  464

Query  482  SPLAAIDSWVNTKCPKCGKEAKRETNTMPQWAGSCWYYLRFIDPHNNEAFADKEKCDYWM  541
            SPLA +  W++       K ++RETNTMPQWAGS WYYLR+IDPHN E +AD E    W+
Sbjct  465  SPLANVTDWLEVTREDGVK-GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWL  523

Query  542  PVDLYVGGTEHAVLHLLYARFWHKVLYDLGLVSTKEPFTRLINQGMITSFAYMRKNKSLV  601
            PVD+YVGG+EHAVLHLLYARFWHKVLYDLG+V+TKEPF +L+NQGMI + +Y     +LV
Sbjct  524  PVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALV  583

Query  602  PVDKVKKISETEFEDIETGEKLEQVIAKMSKSLKNVINPDDIIKEYGADTLRLYEMFLGP  661
            + DKV K  +  F ++ETGE LEQ  AKMSKSLKNV+NPDD++ +YGADTLR+YEMF+GP
Sbjct  584  ATDKVEK-RDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGP  642

Query  662  LEVSKPWNTSGIMGVFRFLEKIWNLSDREIYKTPVNDTSTPETKTLTVLLNKTIKKVTED  721
            L+ S +W+  G+ G  +FL+++  L          ++ +  ++ +L  + N T+K VTE+
Sbjct  643  LDASIAWSEEGLEGSRKFLDRVYRL-------ITTKEITEENSGALDKVYNETVKAVTEQ  695

Query  722  TASLNFNTAISQMMIFINEVSKHKKI-PHYVWYNFVKLLNPYAPHLAEELWQKM-GNDES  779
               ++FNTAI+Q+M+F+N  +K+ K+ ++Y    FV+L+ P+APHL+EELWQ + +++ES
Sbjct  696  VDQMKFNTAIAQLMVFVNAANKEDKLFSDYA-KGFVQLIAPFAPHLGEELWQALTASGES  754

Query  780  IAYSHWPMFVEKFcvdqtctvvvqvNGKLRGKFEAEAGTSKEELERLALSNEGAIRNIEG  839
            I+Y  WP + E   V++   +VVQ++GK+++K+    + S+EEL+ +AL+NE    +I G
Sbjct  755  ISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAG  814

Query  840  KEIKKIITVPDKLVNIVVQ  858
            K+I K+I+VP+KLVNIV++
Sbjct  815  KDIIKVIAVPNKLVNIVIK  833

436) Tresu_0602 in NC_015385


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  753 bits (2850),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 469/890 (53%), Positives = 621/890 (70%), Gaps = 59/890 (6%)

Query  1    MSNYPFQNIEVKWQKYWEENKTFRVEEDKSFSKEKRRYILDMFPYPSGAGLHVGHPEGYT  60
            M+ Y    IE KWQ +W +N TF+   D   +   + Y LDMFPYPSGAGLHVGHPEGYT
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTD---ASKPKFYALDMFPYPSGAGLHVGHPEGYT  57

Query  61   ATDIYSRYLRMNGYNVLHPMGYDSFGLPAENYAIKTGTHPSITTNANIANFTRQIKALGF  120
            ATDI SR+ R +G NVLHPMG D+FGLPAE+YA+ TG +P+  T  NIANF RQI+ALGF
Sbjct  58   ATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGF  117

Query  121  SYDWDRCVSTCEPEYYKWTQWIFLQLYKKGLAYEAATPINWCPSCLTGLANEEV-KEGRC  179
            SYDWDR V+T +P+YYKWTQWIF +LY KGLAYEA  P+NW     T++ANEEV  +G  
Sbjct  118  SYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTS  177

Query  180  ERCGAVVTRKTIRQWILKITDYAERlledldlldWPESVKLMQKNWIGKSCGAEVEFEVA  239
            ER G  V RK +RQW+LKIT YAERLLEDL+ +DWPES+K MQ+NWIGKS GA+V F V 
Sbjct  178  ERGGYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKV-  236

Query  240  GKDGNGSGKYLKVYTTRADTLFGCTYMVMSPEHKMLKELTTPEQKPaveayveeaaKKSD  299
                ++++K + V+TTR+DTLFG TY V++PEH ++  +TT++Q  AV  Y  +A+ KSD
Sbjct  237  ----KDTDKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSD  292

Query  300  LERTDLNKNKTGVFTGSYGIDPVNGAKVPIWISDYVLTSYGTGAIMAVPAHDERDWDFAK  359
            L RTDL K+KTGV TGSY+I+PVNG  +P+WI+DYVL+SYGTGAIMAVPAHDERDW+FAK
Sbjct  293  LARTDLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAK  352

Query  360  KFNLPIIKVIATKEDIVSLGGGDEKKGAELLQAASKNPEEYKKLVDAHPEIFCVANECTS  419
            +FNL II V         L GG+                                +E + 
Sbjct  353  QFNLDIIPV---------LEGGN-------------------------------VEEAAF  372

Query  420  AKDGYSINSEFITGKSTKDAIQEMIKFLEEKKCGKATVNYKLRDWIFSRQRYWGEPIPLV  479
            + DG  INS+F+ G     AI  M+  LE    G+  V Y+LRDW+FSRQRYWGEPIP++
Sbjct  373  TEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPII  432

Query  480  HCEKCGCVPVPEKDLPVKLPDVKSYQPTGTGESPLAAIESWVNTTCPKCGGKAKRETNTM  539
            H E     +VPE +LP+ LP  K  +P+GTGESPLA +  W++ T    G K++RETNTM
Sbjct  433  HWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED-GVKGRRETNTM  491

Query  540  PQWGGSCWYYLRYLDPKNNSEFCSKEKEEYWMPVDLYVGGAEHAVLHLLYARFWHKVLYD  599
            PQW+GS WYYLRY+DP N   +   E    W+PVD+YVGGAEHAVLHLLYARFWHKVLYD
Sbjct  492  PQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYD  551

Query  600  IGAVSTKEPFHRLINQGLITSFAFQRKNKTLVPTDEVEEKDGKYFEKATGEQVEQIIAKM  659
            +G V+TKEPF++L+NQG+I + +++    +LV+TD VE +DG +F+  TGE++EQ  AKM
Sbjct  552  LGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEELEQAPAKM  611

Query  660  SKSLKNVVNPDEMIQKYGADSVRMYEMFMGPLTVSKPWNTQGLVGINRFLEKVWNISEKP  719
            SKSLKNVVNPD+++++YGAD++R+YEMFMGPL  S +W+ +GL G  +FL++V  +    
Sbjct  612  SKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRL----  667

Query  720  MDEIDIKGKLEDKALVALRKTFAQTIKKVTEDTSSLSFNTAISQMMIFINEASKFNSLPK  779
               I  K   E+++  AL K + +T+K VTE+   + FNTAI+Q+M+F+N A+K + L  
Sbjct  668  ---ITTKEITEENS-GALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFS  723

Query  780  EMWKDFVLILSPYAPHLGEELWQKLGGT-KTVAYEKWPSFSEEFCKEDSIQIVVMINGKL  838
            +  K+FV +++P+APHLGEELWQ L ++  +++Y  WPS+ E    E+ ++IVV I+GK+
Sbjct  724  DYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKV  783

Query  839  RDKFEAAPGTDDETLKNLASQTEGYKKFTDGKTIAKVIVVKDKLVNIVAK  888
            + K+  A +   E L+++A   E  +    GK I KVI V +KLVNIV K
Sbjct  784  KAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

437) leuS in NC_014032


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  752 bits (2846),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 477/863 (56%), Positives = 629/863 (73%), Gaps = 37/863 (4%)

Query  3    YPFHDIETKWQQHWEEHQTFRTPDEVPDDQEEFYVLDMFPYPSGSGLHVGHPEGYTATDI  62
            Y    IE KWQ  W +++TF+T  + +  +  FY LDMFPYPSG+GLHVGHPEGYTATDI
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDAS--KPKFYALDMFPYPSGAGLHVGHPEGYTATDI  61

Query  63   VARYKRKQGFNVLHPMGWDAFGLPAEQYALKTNTHPRETTEKNIAQFKRQLKRLGFSYDW  122
            ++R+KR QG NVLHPMGWDAFGLPAEQYA+ T  +P E T  NIA+FKRQ++ LGFSYDW
Sbjct  62   LSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDW  121

Query  123  QREINTTDPDYYKWTQWIFLQLYEKGLAYQSEEPVWWCEELGTVLANEEVI-DGKSERGG  181
            +RE+NTTDP+YYKWTQWIF +LYEKGLAY++E PV W EELGT +ANEEV+ DG SERGG
Sbjct  122  DREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGG  181

Query  182  YPCERVPMRQWVLKITEYADRLLEGLEALDWPESTKEMQRNWIGRSEGANVYFDLVGADD  241
            YP  R PMRQW+LKIT YA+RLLE+LE +DWPES K+MQRNWIG+S GANV F + ++D 
Sbjct  182  YPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDK  241

Query  242  ALEVYTTRPDTLFGATYMVLAPEHELLDEITTDEHREDVNEYCRQALRKSERKRQQQG-D  300
             + V+TTRPDTLFGATY VLAPEH L+D ITT ++ E V +Y RQA  KS+  R + + +
Sbjct  242  DFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKE  301

Query  301  KTGVFTGGYAVNPVNGEEIPIWVADYVLVSYGTGAIMAVPAHDERDHAFAKKYDLPIREV  360
            KTGV TG+YA+NPVNG E+P+W+ADYVL SYGTGAIMAVPAHDERD  FAK+++L I  V
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  361  VEGGDIDEEAYTGDGPHVHSANEAVSLNGLRNEEAKEAITEWLDEEEKGERTVNYQLQDW  420
            +EGG+++E A+T DG H++S      L+GL +  A   + EWL+ E  G+  V Y+L+DW
Sbjct  362  LEGGNVEEAAFTEDGLHINSD----FLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDW  417

Query  421  LFSRQRYWGEPFPIVFTEDGEDKpvpeeelpvtlpdldVFEPSGTPEGPLATIEDWRETT  480
            LFSRQRYWGEP+PI+  EDG   +VPE ELP+ LP    + PSGT E+PLA + DW E T
Sbjct  418  LFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT  477

Query  481  DPETGEPAQRETNTMPQWAGSCWYYLRFIDPDNDEQLVDPEKEEYWMPVDLYVGGSEHAV  540
              E G  ++RETNTMPQWAGS WYYLR+IDP+N E+L D E    W+PVD+YVGG+EHAV
Sbjct  478  -REDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  541  LHLLYARFWHKVLYDAGVVSTKEPFQTLVHQGMILGETEYTAYRDDAGEFVSAEQVDDDA  600
            LHLLYARFWHKVLYD GVV+TKEPFQ L +QGMILG    T+YRD  G +V++++V+   
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILG----TSYRDSRGALVATDKVEKRD  592

Query  601  DLTpvpvddgdvekdgdvfvLADRPAVRVDARSHKMSKSRGNVINPDDVVDEYGADTLRL  660
            +                   +    +  ++  + KMSKS  NV+NPDDVV++YGADTLR+
Sbjct  593  G-----------------SFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRV  635

Query  661  YEMFMGPLEQDKPWSTDDMEGVHRFLNRIWRLVVDADSGGLAVSDEEPDREQLRTLHRTI  720
            YEMFMGPL+   +WS +++EG ++FL+R+ RL+   +     +++E+++  + +  + T+
Sbjct  636  YEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKE-----ITEENSGALD-KVYNETV  689

Query  721  KKVTEDIEARDFNTAIAAMMEFVNAANKWDALPRQVATPFVLLLSPFAPHLAEELWARL-  779
            K VTE+++   FNTAIA +M FVNAANK D L  + A  FV L++PFAPHL+EELW  L 
Sbjct  690  KAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALT  749

Query  780  GHDQSLAYADWPAYDDELIRREVVEMPVQVDGTVRATIevaadaeeadvlaaakeaeNVA  839
            + ++S++Y  WP+YD+  +  + VE+ VQ+ G V+A + VA D    ++   A   E+V 
Sbjct  750  ASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQ  809

Query  840  RHLDDEDLQREIYVPGQIVNFVT  862
             ++ + D+ + I VP ++VN+V 
Sbjct  810  AEIAGKDIIKVIAVPNKLVNIVI  832

438) I871_01340 in NC_022079


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  748 bits (2831),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 456/845 (54%), Positives = 626/845 (75%), Gaps = 15/845 (1%)

Query  1    MSKYNFTEIEKKWQTYWDKHKTYKVYEDPSIPKEKRIYILDMFPYPSANGLHVGHPEGYT  60
            M+ Y+ T IE KWQ++W  + T+K   D+S PK   +Y LDMFPYPS+ GLHVGHPEGYT
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPK---FYALDMFPYPSGAGLHVGHPEGYT  57

Query  61   ATDILTRYKLLNGFNVLHPIGFDSFGLPAENYAIQTGKHPKKITEKNIERFKEQIKALGF  120
            ATDIL+R+K  +G NVLHP+G D+FGLPAE+YA++TG++P  +T  NI  FK QI+ALGF
Sbjct  58   ATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGF  117

Query  121  AYDWDREIRTHDENYYKWTQWIFLKLYKKGLAYTKKMPVWYCPDLGTVLSNEEVIQTPDG  180
            +YDWDRE+ T D NYYKWTQWIF KLY KGLAY   +PV    +LGT ++NEEV+  PDG
Sbjct  118  SYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVL--PDG  175

Query  181  PRSERGFHKVKRKPLKQWILKITEYAERLLKDLEDIDWPESVKEMQKNWIGKSTGAEIEF  240
              SERG   V RKP++QW+LKIT YAERLL DLE++DWPES+K+MQ+NWIGKSTGA++ F
Sbjct  176  T-SERGGYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTF  234

Query  241  SVKASKEKIKVFTTRPDTIFGVTYLVLAPENKIVDKITKDEFKSLISEYKNKEYLKSDLE  300
             VK +   + VFTTRPDT+FG TY VLAPE+ +VD IT  +    +++YK +  LKSDL 
Sbjct  235  KVKDTDKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLA  294

Query  301  RTSLEKDKTGIFTGSYAINPITEEEIPIWIGSYVLGTYGTGAVMSVPAHDERDFEFAKKY  360
            RT L K+KTG+ TGSYAINP+   E+P+WI+ YVL++YGTGA+M+VPAHDERD EFAK++
Sbjct  295  RTDLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQF  354

Query  361  NLEIKQVVSKTGKNEILIKPFTEDGISTNTPQEF-NNLKTTQVKTKVIEWLTknkkgqkk  419
            NL+I  V+     +E    +FTEDG+  N+  +F + L  +   +K++EWL  +  G+ +
Sbjct  355  NLDIIPVLEGGNVEEA---AFTEDGLHINS--DFLDGLDKASAIAKMVEWLEAEGVGNEN  409

Query  420  vnykLRDWIFSRQRYWGEPIPIMLDEDLNEIPLEEDKLPLRLPEIENYKPSGTGESPLSK  479
            V Y+LRDW+FSRQRYWGEPIPI+  ED    ++ E  LPL LP   + +PSGTGESPL++
Sbjct  410  VTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLAN  469

Query  480  NQNWVNV-KHNGKIYKRETNTMPQWAGSCWYYLRYLDPNNEKEFASKETINYWMPVDLYV  538
              +W++V +++G   +RETNTMPQWAGS WYYLRY+DP+N   +A  E ++ W+PVD+YV
Sbjct  470  VTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYV  529

Query  539  GGAEHSVLHLLYARFWHKVLYDLGYVNTKEPFKKLINQGMITSFAYQDENGILIPNDEVE  598
            GGAEH+VLHLLYARFWHKVLYDLG V TKEPF+KL+NQGMI + +Y+D  G L++ D VE
Sbjct  530  GGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVE  589

Query  599  KRNNKFFSKKTNKELKQIVAKMSKSLkniinpdniikkYGADSIRIYEMFMGPLTDSKPW  658
            KR+  FF   T  EL Q  AKMSKSLKN++NPD+++ +YGAD++R+YEMFMGPL  S +W
Sbjct  590  KRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAW  649

Query  659  NTQGLIGVFRFLNKI-WTIKNKELTKEAAPKKLISELQKTIKKVTEDIESLNFNTAISSL  717
            + +GL G  +FL+++ + I  KE+T E +   L    + T+K VTE+++ ++FNTAI+ L
Sbjct  650  SEEGLEGSRKFLDRVYRLITTKEITEENSG-ALDKVYNETVKAVTEQVDQMKFNTAIAQL  708

Query  718  MIFTNEVLKYDKNYLEIFKPLTIILSPFAPHLGEELWEYMEEKSSIFKNAKWPKYDPNLM  777
            M+F N   K DK + +  K +  +++PFAPHLGEELW+ +   +  +    WP YD + +
Sbjct  709  MVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKL  768

Query  778  IDEPREIILQINGKIKDRITLDKETDKEALQDIAFknqkimkniknkqiikiiTVKDKLI  837
            +++  EI++QI+GK+K ++ + K+  +E LQ++A+ N+K+  +I  K+IIK+I+V +KL+
Sbjct  769  VENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLV  828

Query  838  NIVTK  842
            NIV K
Sbjct  829  NIVIK  833

439) leuS in NC_011229


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  747 bits (2826),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 453/845 (54%), Positives = 630/845 (75%), Gaps = 15/845 (1%)

Query  1    MSKYDFKKIEKKWQNYWDKHKTYKVNEDPNVPKEKRIYILDMFPYPSANGLHVGHPEGYT  60
            M+ YD   IE KWQ +W  + T+K   D++ PK   +Y LDMFPYPS+ GLHVGHPEGYT
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPK---FYALDMFPYPSGAGLHVGHPEGYT  57

Query  61   ATDILTRYKLLNGFNVLHPMGFDSFGLPAENYAIQTGKHPKKITEKNIEKFKEQIKALGF  120
            ATDIL+R+K  +G NVLHPMG D+FGLPAE+YA++TG++P  +T  NI +FK QI+ALGF
Sbjct  58   ATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGF  117

Query  121  AYDWDREIKTHDVNYYKWTQWIFLQLYKKGLAYTKEIPVWYCPDLGTVLANEEVIQTPDG  180
            +YDWDRE++T D NYYKWTQWIF +LY KGLAY  E+PV    +LGT +ANEEV+  PDG
Sbjct  118  SYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVL--PDG  175

Query  181  PRSERGFHKVERKPLRQWLLKITKYAERLIRDLEEVDWPDSVKEMQKNWIGKSTGVEIEF  240
              SERG   V RKP+RQW+LKIT YAERL+ DLEEVDWP+S+K+MQ+NWIGKSTG ++ F
Sbjct  176  T-SERGGYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTF  234

Query  241  LIKESKEKIKVFTTRPDTIFGVTYLVLAPEHPMVDKITKDELKPIISKYKDKEILKSDLE  300
             +K++   + VFTTRPDT+FG TY VLAPEH++VD IT  +    ++ YK +  LKSDL 
Sbjct  235  KVKDTDKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLA  294

Query  301  RTSLEKDKTGIFTGAYAINPITKEEIPIWIGSYILGTYGTGAVMSVPAHDERDFEFAKKY  360
            RT L K+KTG+ TG+YAINP+   E+P+WI+ Y+L++YGTGA+M+VPAHDERD EFAK++
Sbjct  295  RTDLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQF  354

Query  361  NLPIKQVVSQTGTNEVLIKPFTENGISINTPTEF-NNLKTIEVKTKVIKWLIENKMGQEK  419
            NL I  V+     +E    +FTE+G+ IN+  +F + L      +K++ WL  + +G+E+
Sbjct  355  NLDIIPVLEGGNVEEA---AFTEDGLHINS--DFLDGLDKASAIAKMVEWLEAEGVGNEN  409

Query  420  VNYKLRDWIFSRQRYWGEPIPILFDDNLNEIPLNDDELPLTLPDIENYKPSGTGESPLSK  479
            V Y+LRDW+FSRQRYWGEPIPI+  ++    ++ + ELPL LP   + +PSGTGESPL++
Sbjct  410  VTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLAN  469

Query  480  IKDWVNVKRNGKI-YKRETNTMPQWAGSCWYYIRYLDPHNKKEFANKEKINYWMPVDLYI  538
            + DW++V R++ +  +RETNTMPQWAGS WYY+RY+DPHN   +A+ E ++ W+PVD+Y+
Sbjct  470  VTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYV  529

Query  539  GGAEHSVLHLLYARFWHKVLYDLGYVNTKEPFRKLINQGMITSFAYQDENGILIPNDEVe  598
            GGAEH+VLHLLYARFWHKVLYDLG V TKEPF+KL+NQGMI + +Y+D  G L++ D VE
Sbjct  530  GGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVE  589

Query  599  kkdnkffskknnkelkQIIAKMSKSLKNIINPDDIIKEYGADSMRIYEMFMGPLTDSKPW  658
            K+D  FF      EL Q  AKMSKSLKN++NPDD++ +YGAD++R+YEMFMGPL  S +W
Sbjct  590  KRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAW  649

Query  659  NTQGLIGIFRFLNKI-WLIKNKELTNETPPKEIISELHKTIKKVTEDIETLNFNTAISTL  717
            + +GL G  +FL+++ +LI  KE+T+E +   +    + T+K VTE+++ ++FNTAI+ L
Sbjct  650  SEEGLEGSRKFLDRVYRLITTKEITEENSG-ALDKVYNETVKAVTEQVDQMKFNTAIAQL  708

Query  718  MIFINELLKHEKNYLKIFRPISIILSPFAPHLGEELWEFMGEQSSIFKNAKWPKYDLNSI  777
            M+F+N   K++K +    + +  +++PFAPHLGEELW+ +   +  +    WP YD + +
Sbjct  709  MVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKL  768

Query  778  IDDTREIVLQVNGktkdkimikkdtdEETLkkiafnnqkiiqninnkqiikiiTVKDKLV  837
            +++  EIV+Q++GK K K+++ KD   E L+ +A+ N+K+  +I  K+IIK+I+V +KLV
Sbjct  769  VENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLV  828

Query  838  NIVAK  842
            NIV K
Sbjct  829  NIVIK  833

440) leuS in NC_005861


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  747 bits (2828),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 457/849 (54%), Positives = 616/849 (73%), Gaps = 25/849 (2%)

Query  3    YDHQQIEAKWQKFWQDNQTYRSDDNFQKPKYYVLDMFPYPSGAGLHVGHVVGYTATDIIA  62
            YDH  IE+KWQ FW DN+T++++ +  KPK+Y LDMFPYPSGAGLHVGH  GYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYMRTKGYNVMHPMGWDSFGLPAEQYAIRTGTHPAESTQENINNYRRQLRALGFSYDWNR  122
            R+ R++G NV+HPMGWD+FGLPAEQYA+ TG +PAE T ENI N++RQ+ ALGFSYDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  ELATSDPNYYKWTQWIFTKLYEKGLAYEAEMLVNYCPALGTVLANEEI-ENGKTKDGGHP  181
            E+ T+DPNYYKWTQWIFTKLYEKGLAYEAE+ VN    LGT +ANEE+  +G +  GG P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRPLKQWILKITAYAdrllqdldlldWPESLKKLQINWIGKSEGAYVQFIEKTTQEAF  241
            V R+P++QW+LKITAYA+RLL+DL+ +DWPES+K +Q NWIGKS GA V F  K T+  F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  SVFTTRPDTLFGVSYLVLAPEHPLVSHITASSQQQAVRAYQAQIASKSDLDRTELNRDKT  301
            +VFTTRPDTLFG +Y VLAPEH+LV  IT+S Q +AV  Y+ Q + KSDL RT+L ++KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAVNPVNHKEIPIWISDYVLMNVGTGAIMAVPAHDERDFEFAKTFKLPIIPVYD  361
            GV TG+YA+NPVN KE+P+WI+DYVL + GTGAIMAVPAHDERD EFAK F+L IIPV +
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  PVCEEITIRNQVLAGQQCWPGHGICVNSACGDLSLNGLNLDQAKKIVINWLEINHKGKSA  421
                E          +     +G+ +NS      L+GL+   A   +++WLE +  G+  
Sbjct  364  GGNVE----------EAAFTEDGLHINSDF----LDGLDKASAIAKMVEWLEAEGVGNEN  409

Query  422  TTYKLRDWLFSRQRYWGEPFPLLKFEDGSVRlldedelplcppAITNYKPTGDGKGPLTQ  481
             TY+LRDWLFSRQRYWGEP+P++  EDG+   + E ELPL  P   + +P+G G +PL++
Sbjct  410  VTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLAN  469

Query  482  IKEWVEIIDTKTGKKAFRDTNIMPQWAGSCWYYLRFCDPHNTEKAFSPEKEKYWLPVDLY  541
            + +W+E+     G K+ R+TN MPQWAGS WYYLR+ DPHNTEK    E  K WLPVD+Y
Sbjct  470  VTDWLEVT-REDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIY  528

Query  542  IGGVEHAVLHLLYARFWHKVLYDCGYVHTLEPFQTLRNQGLVVARSYQNKMRVYVEPRYV  601
            +GG EHAVLHLLYARFWHKVLYD G V T EPFQ L NQG++++ SY++     V    V
Sbjct  529  VGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKV  588

Query  602  EQRDGKYFDSRTGEELTSQIDKMSKSKLNGESPDEIIQEYGADALRLYEMFMGPLEKEKV  661
            E+RDG +F+  TGEEL     KMSKS  N  +PD+++++YGAD+LR+YEMFMGPL+    
Sbjct  589  EKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIA  648

Query  662  WNTDAVSGTRRFLNRFYEMAFSDKVTNETSEEGLKLGHRLVHSVMKDMELLQFNTAIAKM  721
            W+ +++ G+R+FL+R Y +  +  +T+E S    K+ +  V +V  +++ ++FNTAIA++
Sbjct  649  WSEEGLEGSRKFLDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQL  708

Query  722  MEFINEFTK----LVTYPKQVIQMATQVLAPFAPHLAEEVWEHLKCEG-SLSFTPYPQVE  776
            M F+N   K    +  Y+K  +Q+    +APFAPHL+EE+W+ L   G S+S+ P P  +
Sbjct  709  MVFVNAANKEDKLFSDYAKGFVQL----IAPFAPHLGEELWQALTASGESISYVPWPSYD  764

Query  777  EKYLQENVITYVVQINGKVRGRFDLPKDQTQENVLEAAKNNPHIQQYINKKEIGKVVFVP  836
            E  L EN +  VVQI+GKV++++ ++KD ++E++ E A  N  +Q  I  K+I KV+ VP
Sbjct  765  ESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVP  824

Query  837  NKLLSIVLR  845
            NKL++IV++
Sbjct  825  NKLVNIVIK  833

441) leuS in NC_008710


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  746 bits (2821),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 458/845 (55%), Positives = 630/845 (75%), Gaps = 15/845 (1%)

Query  1    MSEYNFTKIEKKWQNYWDKHKTYKVNEDPNIPKEKRIYILDMFPYPSANGLHVGHPEGYT  60
            M+ Y+ T IE KWQ +W  + T+K   D++ PK   +Y LDMFPYPS+ GLHVGHPEGYT
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPK---FYALDMFPYPSGAGLHVGHPEGYT  57

Query  61   ATDILTRYKLLNGFNVLHPMGFDSFGLPAENYAIQTGEHPKKITEKNIEKFKEQIKALGF  120
            ATDIL+R+K  +G NVLHPMG D+FGLPAE+YA++TG++P  +T  NI +FK QI+ALGF
Sbjct  58   ATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGF  117

Query  121  AYDWDREIRTHDENYYKWTQWIFLKLYKKGLAYIKEMPVWYCPDLGTVLSNEEVIQTPDG  180
            +YDWDRE+ T D NYYKWTQWIF KLY KGLAY  E+PV    +LGT ++NEEV+  PDG
Sbjct  118  SYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVL--PDG  175

Query  181  PRSERGFHKVQRKPLRQWVLKITEYAERLIKDLEEIDWPESVKEMQKNWIGKSIGAEIEF  240
              SERG   V RKP+RQW+LKIT YAERL+ DLEE+DWPES+K+MQ+NWIGKS GA++ F
Sbjct  176  T-SERGGYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTF  234

Query  241  SIKASKEKIKVFTTRPDTIFGVTYLVLAPEHNIVDKITKDELKTIIAEYKDKEILKSDLE  300
             +K +   + VFTTRPDT+FG TY VLAPEH +VD IT  +    +A+YK +  LKSDL 
Sbjct  235  KVKDTDKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLA  294

Query  301  RTSLEKDKTGVFTGAYAINPITEEEIPIWIGSYVLGIYGTGAVMSVPAHDERDFEFAKKY  360
            RT L K+KTGV TG+YAINP+   E+P+WI+ YVL+ YGTGA+M+VPAHDERD EFAK++
Sbjct  295  RTDLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQF  354

Query  361  NLPIKQVVSQTGNNEILTKPFTENGISINTPEEF-NNLKTEKVKTKVIEWLTknkkgqkk  419
            NL I  V+     +E    +FTE+G+ IN+  +F + L      +K++EWL  +  G+ +
Sbjct  355  NLDIIPVLEGGNVEEA---AFTEDGLHINS--DFLDGLDKASAIAKMVEWLEAEGVGNEN  409

Query  420  vnykLRDWIFSRQRYWGepipiiidddlneipleedelplrlpeieNYKPSDTGESPLSK  479
            V Y+LRDW+FSRQRYWGEPIPII  +D    ++ E ELPL LP   + +PS+TGESPL++
Sbjct  410  VTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLAN  469

Query  480  VQNWVNVKRNGKI-YKRETNTMPQWAGSCWYYIRYLDPNNEKEFASKEKINYWMPVDLYI  538
            V +W++V R++ +  +RETNTMPQWAGS WYY+RY+DP+N   +A  E ++ W+PVD+Y+
Sbjct  470  VTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYV  529

Query  539  GGAEHSVLHLLYARFWHKVLYDLGYVNTKEPFKKLINQGMITSFAYQDENGILIPNDEVK  598
            GGAEH+VLHLLYARFWHKVLYDLG V TKEPF+KL+NQGMI + +Y+D  G L++ D V 
Sbjct  530  GGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVE  589

Query  599  KRDNKFFSKTNNKELKQIIAKMSKSLKNIINPDDIIKEYGADSMRIYEMFMGPLTDSKPW  658
            KRD  FF      EL Q  AKMSKSLKN++NPDD++ +YGAD++R+YEMFMGPL  S +W
Sbjct  590  KRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAW  649

Query  659  NTQGLIGIFRFLNKI-WAIKNKELTKESAAKEIISGLHKTIKKVTEDIENLNFNTAISSL  717
            + +GL G  +FL+++ + I  KE+T E+++  +    + T+K VTE++++++FNTAI+ L
Sbjct  650  SEEGLEGSRKFLDRVYRLITTKEITEENSG-ALDKVYNETVKAVTEQVDQMKFNTAIAQL  708

Query  718  MIFINELLKHDKNYLEIFKPLTIILAPFAPHLGEELWEYMGEQPSIFKNAKWPKYDPNLI  777
            M+F+N   K+DK + +  K +  ++APFAPHLGEELW+ +      +    WP YD + +
Sbjct  709  MVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKL  768

Query  778  IDNTREIVLQVNGKIKDKIILNKGINEDTLKDIALknhkimqniqnkqiikiiTVKDKLI  837
            ++N  EIV+Q++GK+K K+++ K+++ + L+++AL N+K+  +I  K+IIK+I+V +KL+
Sbjct  769  VENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLV  828

Query  838  NIVTK  842
            NIV K
Sbjct  829  NIVIK  833

442) leuS in NC_011244


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  746 bits (2821),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 428/793 (54%), Positives = 592/793 (75%), Gaps = 15/793 (1%)

Query  1    MSKYDFKKIEKKWQNYWDKHKTYKVNEDPNVPKEKRIYILDMFPYPSANGLHVGHPEGYT  60
            M+ YD   IE KWQ +W  + T+K   D++ PK   +Y LDMFPYPS+ GLHVGHPEGYT
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPK---FYALDMFPYPSGAGLHVGHPEGYT  57

Query  61   ATDILTRYKLLNGFNVLHPMGFDSFGLPAENYAIQTGKHPKKITEKNIEKFKEQIKALGF  120
            ATDIL+R+K  +G NVLHPMG D+FGLPAE+YA++TG++P  +T  NI +FK QI+ALGF
Sbjct  58   ATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGF  117

Query  121  AYDWDREIKTHDVNYYKWTQWIFLQLYKKGLAYTKEIPVWYCPDLGTVLANEEVIQTPDG  180
            +YDWDRE++T D NYYKWTQWIF +LY KGLAY  E+PV    +LGT +ANEEV+  PDG
Sbjct  118  SYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVL--PDG  175

Query  181  PRSERGFHKVERKPLRQWLLKITKYAERLIRDLEEVDWPDSVKEMQKNWIGKSTGVEIEF  240
              SERG   V RKP+RQW+LKIT YAERL+ DLEEVDWP+S+K+MQ+NWIGKSTG ++ F
Sbjct  176  T-SERGGYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTF  234

Query  241  LIKESKEKIKVFTTRPDTIFGVTYLVLAPEHPMVDKITKDELKPIISKYKDKEILKSDLE  300
             +K++   + VFTTRPDT+FG TY VLAPEH++VD IT  +    ++ YK +  LKSDL 
Sbjct  235  KVKDTDKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLA  294

Query  301  RTSLEKDKTGIFTGAYAINPITKEEIPIWIGSYILGTYGTGAVMSVPAHDERDFEFAKKY  360
            RT L K+KTG+ TG+YAINP+   E+P+WI+ Y+L++YGTGA+M+VPAHDERD EFAK++
Sbjct  295  RTDLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQF  354

Query  361  NLPIKQVVSQTGTNEVLIKPFTENGISINTPTEF-NNLKTIEVKTKVIKWLIENKMGQEK  419
            NL I  V+     +E    +FTE+G+ IN+  +F + L      +K++ WL  + +G+E+
Sbjct  355  NLDIIPVLEGGNVEEA---AFTEDGLHINS--DFLDGLDKASAIAKMVEWLEAEGVGNEN  409

Query  420  VNYKLRDWIFSRQRYWGEPIPILFDDNLNEIPLNDDELPLTLPDIENYKPSGTGESPLSK  479
            V Y+LRDW+FSRQRYWGEPIPI+  ++    ++ + ELPL LP   + +PSGTGESPL++
Sbjct  410  VTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLAN  469

Query  480  IKDWVNVKRNGKI-YKRETNTMPQWAGSCWYYIRYLDPHNEKEFANKEKINYWMPVDLYI  538
            + DW++V R++ +  +RETNTMPQWAGS WYY+RY+DPHN   +A+ E ++ W+PVD+Y+
Sbjct  470  VTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYV  529

Query  539  GGAEHSVLHLLYARFWHKVLYDLGYVNIKEPFRKLINQGMITSFAYQDENGILIPNDEVe  598
            GGAEH+VLHLLYARFWHKVLYDLG V  KEPF+KL+NQGMI + +Y+D  G L++ D VE
Sbjct  530  GGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVE  589

Query  599  kkdnkffskknnkelkQIIAKMSKSLKNIINPDDIIKEYGADSMRIYEMFMGPLTDSKPW  658
            K+D  FF      EL Q  AKMSKSLKN++NPDD++ +YGAD++R+YEMFMGPL  S +W
Sbjct  590  KRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAW  649

Query  659  NTQGLIGIFRFLNKI-WLIKNKELTNETPPKEIISELHKTIKKVTEDIETLNFNTAISTL  717
            + +GL G  +FL+++ +LI  KE+T+E +   +    + T+K VTE+++ ++FNTAI+ L
Sbjct  650  SEEGLEGSRKFLDRVYRLITTKEITEENSG-ALDKVYNETVKAVTEQVDQMKFNTAIAQL  708

Query  718  MIFINELLKHEKNYLKIFRPISIILSPFAPHLGEELWEFMGEQSSIFKNAKWPKYDLNSI  777
            M+F+N   K++K +    + +  +++PFAPHLGEELW+ +   +  +    WP YD + +
Sbjct  709  MVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKL  768

Query  778  IDDTREIVLQVNG  790
            +++  EIV+Q++G
Sbjct  769  VENDVEIVVQIKG  781

443) leuS in NC_008380


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  746 bits (2822),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 448/838 (54%), Positives = 608/838 (73%), Gaps = 14/838 (1%)

Query  3    YDPTKIEPKWQAYWAGHHIFRVEIDPARPKFYALDMFPYPSGAGLHVGHPLGYTATDIMC  62
            YD T IEPKWQA+WA++H F+   D+++PKFYALDMFPYPSGAGLHVGHP GYTATDI+ 
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRMRGFNVLHPMGWDSFGLPAERHAMRTGVHPDITTKRNIETFRGQVQRLGFSYDWSR  122
            R+KR +G NVLHPMGWD+FGLPAE+ AM TG +P   T  NI  F+ Q++ LGFSYDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EFATTDPAYVRWTQWIFLKLFENGLAYQAEVAVNWCPAQNAVLADEEV-KDGRYVETGDP  181
            E  TTDP Y +WTQWIF KL+E+GLAY+AEV+VNW     + +A+EEV  DG     G P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VIRRRMRQWMLRITAYADRLLQGLDGLDWPENLKAMQRNWIGRSEGAEIRFPLEHGKGVI  241
            V+R+ MRQWML+ITAYA+RLL++L+ +DWPE++K MQRNWIG+S GA++ F + +    +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  TVFTTRPETLFGASYILLAPEHPAVAAIVEPEMSEAVAAYIAEAEGLEETVRADAGREKT  301
            TVFTTRP+TLFGA+Y +LAPEH+ V AI  ++ +EAVA Y  +A    +  R+D ++EKT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYAINPANGARLPVWVADYVLAGYGTGALMAVPAHDARDYAFAHSHELPIIRVID  361
            GV TG+YAINP NG  +PVW+ADYVLA+YGTGA+MAVPAHD RD  FA   +L II V++
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  SEADIEKGAYEGEGAMVNSGFLSGLGSPEARSAIVAWLQANGTGWPKVMYRLRDWLFSRQ  421
            + +++E +A+  +G  +NS+FL GL+ + A + +V WL+A+G G  +V YRLRDWLFSRQ
Sbjct  364  G-GNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQ  422

Query  422  RYWGEPIPVLHLADGSVMplpeeclpllppelDDYAPTPDGEPPLARAQAWVETIVPGTD  481
            RYWGEPIP++H  DG+  ++PE  LPL+ P   D  P+  GE+PLA    W+E +    +
Sbjct  423  RYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE-VTREDG  481

Query  482  IPARRETNTMPQWAGSCWYYLRFLDPENTSEPVGREAERYWMPVDLYVGGAEHAVLHLLY  541
            + +RRETNTMPQWAGS WYYLR++DP+NT    + E  + W+PVD+YVGGAEHAVLHLLY
Sbjct  482  VKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLY  541

Query  542  ARFWHKVLYDIGVVSTEEPFQRLFNQGMILAHSYRDAAGRYYAPSSVVEEEGRWF--AGS  599
            ARFWHKVLYD+GVV+T EPFQ+LFNQGMIL+ SYRD+ G   A   V   +G  F    +
Sbjct  542  ARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETG  601

Query  600  VEVQRAVEKMSKSQLNVVNPDDVVHQFGADALRLYEMFMGPLDAAKPWQTAGVIGVRRFL  659
             E+++A  KMSKS  NVVNPDDVV+Q+GAD+LR+YEMFMGPLDA+ +W   G+ G R+FL
Sbjct  602  EELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFL  661

Query  660  ERAWRIVCDESDGLSPVVLEAAPSPQLLRLRHQTVKTVTADIEAIRFNTAVSRLMELANA  719
            +R  R++           +    S  L ++ ++TVK+VT +++ ++FNTA+++LM + NA
Sbjct  662  DRVYRLITTKE-------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNA  714

Query  720  LTAEAARPREVVETFVLLLAPFAPHIAEELWSKL-GHGETLTWVSWPTFDPALIEMETRE  778
               E     +    FV L+APFAPH++EELW  L + GE+++ V+WP++D + +  +  E
Sbjct  715  ANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVE  774

Query  779  YVVQINGKVRHRFEaaadlgeallaaaR-SEPSVMALLDGKTVVKEVLVPGRLVNFVV  835
             VVQI+GKV+ ++  A DL+   L     ++  V A + GK ++K + VP +LVN+V+
Sbjct  775  IVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

444) leuS in NC_006156


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  745 bits (2820),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 419/816 (52%), Positives = 599/816 (74%), Gaps = 15/816 (1%)

Query  1    MSKYEFIKIEKKWQEFWDNNKTYKVKEDPNIPKEKRLYILDMFPYPSANGLHVGHPEGYT  60
            M+ Y+   IE KWQ FW +N T+K   D++ PK   +Y LDMFPYPS+ GLHVGHPEGYT
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPK---FYALDMFPYPSGAGLHVGHPEGYT  57

Query  61   ATDIFGRYKLLNGFHVLHPIGFDSFGLPAENYAIQTGTHPQKSTEENINKFKKQIKALGF  120
            ATDI++R+K  +G +VLHP+G D+FGLPAE+YA++TG +P   T ENI +FK+QI+ALGF
Sbjct  58   ATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGF  117

Query  121  AYDWDREIRTHDENYYKWTQWIFLELYKKGLAYAKEMPVWYCPELGTVLANEEIIQTPDG  180
            +YDWDRE+ T D NYYKWTQWIF  LY KGLAY  E+PV    ELGT +ANEE++  PDG
Sbjct  118  SYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVL--PDG  175

Query  181  PKSERGFHNVEKKYLRQWVLKITKYAERLLNDLEELEWPESVKEMQRNWIGKSTGVEIDF  240
              SERG   V +K +RQW+LKIT YAERLL+DLEE++WPES+K+MQRNWIGKSTG ++ F
Sbjct  176  T-SERGGYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTF  234

Query  241  EIEGHNDKIKVFTTRPDTIFGITYLVIAPESKLIEKITKNNFKRNVLKYVKHEELKSDLK  300
             + + +  + VFTTRPDT+FG TY V+APE  L++ IT ++    V  Y ++  LKSDL 
Sbjct  235  KVKDTDKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLA  294

Query  301  RTSLEKDKSGVFTGSYAFHPITNEKIPIWIGSYVLGTYGSGAVMGVPAHDERDFQFAKKY  360
            RT L K+K+GV TGSYA++P+    +P+WI+ YVL++YG+GA+M+VPAHDERD +FAK++
Sbjct  295  RTDLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQF  354

Query  361  KLKILPVISKSGKNEILEKAFIDDGISINSPNEF-NNLKNSEVKDKVIEWLIKNKKGKEK  419
            +L I+PV+  +   ++ E AF +DG+ INS  +F + L ++    K++EWL  +  G+E+
Sbjct  355  NLDIIPVLEGG---NVEEAAFTEDGLHINS--DFLDGLDKASAIAKMVEWLEAEGVGNEN  409

Query  420  VTYKLRDWIFSRQRYWGEPIPILFDKLGNAVPLEKNDLPLKLPKTANYKPSRTGESPLSR  479
            VTY+LRDW+FSRQRYWGEPIPI+    G + ++  ++LPL LP T + +PS TGESPL+ 
Sbjct  410  VTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLAN  469

Query  480  IKDWVNL-KDTGFT--RETNTMPQWAGSCWYYLRYLDPKNPKEFASKKKIEYWMPVDLYI  536
            + DW+++ ++ G    RETNTMPQWAGS WYYLRY+DP N   +A    +  W+PVD+Y+
Sbjct  470  VTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYV  529

Query  537  GGAEHTVLHLLYSRFWHKVLYDLGYVNTKEPFKKLINQGIITAFSYQKENGILIPNDQVI  596
            GGAEH+VLHLLY+RFWHKVLYDLG V TKEPF+KL+NQG+I + SY+   G L++ D+V 
Sbjct  530  GGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVE  589

Query  597  EKNSKFFDKRDNKEVIQVIAKMSKSLKNVINPDDIIKEFGADSIRIYEMFMGPLTDSKPW  656
             +++ FF+     E+ Q  AKMSKSLKNV+NPDD++ ++GAD++R+YEMFMGPL  S +W
Sbjct  590  KRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAW  649

Query  657  NTKGIIGVFRFLNKIWNLREKELSKDNPPKEIISQLHKAIKKVTEDTEKLSFNTAISAMM  716
            +  G+ G  +FL+++  L       ++ +  +    + ++K VTE+ +++ FNTAI+ +M
Sbjct  650  SEEGLEGSRKFLDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLM  709

Query  717  IFVNELIKYEKNYLNIFKPFIIILSPYAPHLAEELWEYIGETPSLFKNSKWPEFDENLII  776
            +FVN   K +K + +  K F+ +++P+APHL+EELW+ +  +   +    WP +DE+ ++
Sbjct  710  VFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLV  769

Query  777  KDAKEIVLQINGKMKDKILLSKETDEEELKEIAMGN  812
             +  EIV+QI+GK+K K++++K+   EEL+E+A++N
Sbjct  770  ENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALAN  805

445) Q7M_254 in NC_017808


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  744 bits (2816),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 453/845 (54%), Positives = 629/845 (75%), Gaps = 15/845 (1%)

Query  1    MSKYDFKKIEKKWQNYWDKHKTYKVNEDPNVPKEKRIYILDMFPYPSANGLHVGHPEGYT  60
            M+ YD   IE KWQ +W  + T+K   D++ PK   +Y LDMFPYPS+ GLHVGHPEGYT
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPK---FYALDMFPYPSGAGLHVGHPEGYT  57

Query  61   ATDILTRYKLLNGFNVLHPMGFDSFGLPAENYAIQTGKHPKKITEKNIEKFKEQIKALGF  120
            ATDIL+R+K  +G NVLHPMG D+FGLPAE+YA++TG++P  +T  NI +FK QI+ALGF
Sbjct  58   ATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGF  117

Query  121  AYDWDREIKTHDVNYYKWTQWIFLQLYKKGLAYTKEIPVWYCPDLGTVLANEEVIQTPDG  180
            +YDWDRE++T D NYYKWTQWIF +LY KGLAY  E+PV    +LGT +ANEEV+  PDG
Sbjct  118  SYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVL--PDG  175

Query  181  PRSERGFHKVERKPLRQWLLKITKYAERLIRDLEEVDWPDSVKEMQKNWIGKSTGVEIEF  240
              SERG   V RKP+RQW+LKIT YAERL+ DLEEVDWP+S+K+MQ+NWIGKSTG ++ F
Sbjct  176  T-SERGGYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTF  234

Query  241  LVKESKEKIKVFTTRPDTIFGVTYLVLAPEHPMVDKITKDELKPIISKYKDKEILKSDLE  300
             VK++   + VFTTRPDT+FG TY VLAPEH++VD IT  +    ++ YK +  LKSDL 
Sbjct  235  KVKDTDKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLA  294

Query  301  RTSLEKDKTGMFTGAYAINPITKEEIPIWIGSYILGTYGTGAVMSVPAHDERDFEFAKKY  360
            RT L K+KTG+ TG+YAINP+   E+P+WI+ Y+L++YGTGA+M+VPAHDERD EFAK++
Sbjct  295  RTDLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQF  354

Query  361  NLPIKQVVSQTGNNEVLIKPFTENGISINTPTEF-NNLKTIEVKTKVIKWLIENKMGQEK  419
            NL I  V+     +E    +FTE+G+ IN+  +F + L      +K++ WL  + +G+E+
Sbjct  355  NLDIIPVLEGGNVEEA---AFTEDGLHINS--DFLDGLDKASAIAKMVEWLEAEGVGNEN  409

Query  420  VNYKLRDWIFSRQRYWGEPIPILFDDKLNEIPLNDDELPLTLPDIENYKPSGTGESPLSK  479
            V Y+LRDW+FSRQRYWGEPIPI+  +     ++ + ELPL LP   + +PSGTGESPL++
Sbjct  410  VTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLAN  469

Query  480  IKDWVNVKRNGKI-YKRETNTMPQWAGSCWYYIRYLDPHNDKEFANKEKINYWMPVDLYI  538
            + DW++V R++ +  +RETNTMPQWAGS WYY+RY+DPHN   +A+ E ++ W+PVD+Y+
Sbjct  470  VTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYV  529

Query  539  GGAEHSVLHLLYARFWHKVLYDLGYVNTKEPFRKLINQGMITSFAYQDENGILIPNDEVe  598
            GGAEH+VLHLLYARFWHKVLYDLG V TKEPF+KL+NQGMI + +Y+D  G L++ D VE
Sbjct  530  GGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVE  589

Query  599  kkdnkffskknnkelkQIIAKMSKSLKNIINPDDIIKEYGADSMRIYEMFMGPLTDSKPW  658
            K+D  FF      EL Q  AKMSKSLKN++NPDD++ +YGAD++R+YEMFMGPL  S +W
Sbjct  590  KRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAW  649

Query  659  NTQGLIGIFRFLNKI-WLIKNKELTNETPPKEIISELHKTIKKVTEDIETLNFNTAISTL  717
            + +GL G  +FL+++ +LI  KE+T+E +   +    + T+K VTE+++ ++FNTAI+ L
Sbjct  650  SEEGLEGSRKFLDRVYRLITTKEITEENSG-ALDKVYNETVKAVTEQVDQMKFNTAIAQL  708

Query  718  MIFINELLKHEKNYLKIFRPISIILSPFAPHLGEELWEFMGEQSSIFKNAKWPKYDLNSI  777
            M+F+N   K++K +    + +  +++PFAPHLGEELW+ +   +  +    WP YD + +
Sbjct  709  MVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKL  768

Query  778  IDDTREVVLQVNGktkdkimikkdtdEETLkkiafnnqkiiqninnkqiikiiTVKDKLV  837
            +++  E+V+Q++GK K K+++ KD   E L+ +A+ N+K+  +I  K+IIK+I+V +KLV
Sbjct  769  VENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLV  828

Query  838  NIVAK  842
            NIV K
Sbjct  829  NIVIK  833

446) Emin_0201 in NC_010644


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  743 bits (2810),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 440/831 (53%), Positives = 600/831 (73%), Gaps = 8/831 (0%)

Query  8    EIDKKQQKIWEDNNLFVTPRLPINPKFYCLDMFPYPSGQGLHVGHPEGYTASDILVRYKK  67
             I+ K Q +W DN+ F T   + +PKFY LDMFPYPSG GLHVGHPEGYTA+DIL R+K+
Sbjct  8    AIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSRFKR  67

Query  68   MKGFDVIHPMGWDAFGLPAENYAIATGVHPAITTKNNIDNFRRQIKSLGMAYDWTREIDT  127
             +G +V+HPMGWDAFGLPAE+YA+ TG +PA  T +NI NF+RQI++LG +YDW RE++T
Sbjct  68   AQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDREVNT  127

Query  128  TDPNYYRWTQWIFLQIFKKGLAYESTVPINWCPSCKTGLANEEVF-NGNCERCGTKIESK  186
            TDPNYY+WTQWIF +++ KGLAYE+ VP+NW     T++ANEEV+ +G  ER G  +  K
Sbjct  128  TDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRK  187

Query  187  NIRQWVLKITEYADRLLEDLEGLDWPESTLAMQRNWIGKSIGAEVDFEIDGHKENLKVFT  246
             +RQW+LKIT YA+RLLEDLE +DWPES   MQRNWIGKS GA+V F + +   ++ VFT
Sbjct  188  PMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFT  247

Query  247  TRPDTLFGATYMVVSPEHPILEQITMPEQKAAVKSYQEEAAAKTDFERGDVNK-KTGVFT  305
            TRPDTLFGATY V++PEH++++ IT ++Q  AV  Y+ +A+ K+D+ R D+ K KTGV T
Sbjct  248  TRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVWT  307

Query  306  GAYAINPVNGKKIQIWTSDYVLMGYGTGAIMAVPAHDERDYEFAKKFGLEIIEVIKSDKG  365
            G+YAINPVNGK + +W +DYVL +YGTGAIMAVPAHDERD EFAK+F L+II V+ +++ 
Sbjct  308  GSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGN-  366

Query  366  VEKEAFTGDGELVNSDFLNGMKVEQSKAAMIKFLEEKGVGGAKTTYRLRDWVFSRQRYWG  425
            VE  AFT DG  +NSDFL+G+    + A M+  LE  GVG  + TYRLRDW+FSRQRYWG
Sbjct  367  VEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWG  426

Query  426  EPIPIVHCPKCGVVPVPESELPVKLPEVTNYEPTGTGESPLANVPEWVNTVCPVCAGPAK  485
            EPIPI+H       +VPESELP+ LP   +  P+GTGESPLANV +W++ V    +  ++
Sbjct  427  EPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE-VTREDGVKGR  485

Query  486  RETNTMPQWAGSCWYYLRYLDPKNDKTFVNPEIERECDPVDCYIGGAEHAVLHLLYSRFW  545
            RETNTMPQWAGS WYYLRY+DP N   + + E+ ++  PVD Y+GGAEHAVLHLLY+RFW
Sbjct  486  RETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFW  545

Query  546  HKVLYDLGYVKYKEPYAKLRHQGMILAYSYRGEDGVYHGYDEVDLSDLQNPKLKTTGEKL  605
            HKVLYDLG V  KEP+ KL +QGMIL+ SYR+  G   + D V+  D     +  TGE L
Sbjct  546  HKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVE-TGEEL  604

Query  606  NSMVEKMSKSKKNVINPDDILHKYGADAFRMYEMFMGPFEASKPWDMKGIEGVNRFLKRV  665
            +    KMSKS KNV+NPDD++++YGAD++R+YEMFMGP++AS +W   G+EG  +FL RV
Sbjct  605  EQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRV  664

Query  666  YAWGESVETDEVFLSTKELDILRSKTIVKVSEDIEKFNFNTAVSALMIYFNDLSKIKGVP  725
            Y    + E  E   ++  LD + + T+  V+E++++ +FNTA++ LM++ N  +K   + 
Sbjct  665  YRLITTKEITEE--NSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLF  722

Query  726  LKHFKTFLALLHPFAPHITEELWSR-RKCGPFLVKTAWPEADIMLLRSEDMGLGIQVNGK  784
                K F+ L+ PFAPH+ EELW      G  +   +WP  D   L  +D+ + +Q++GK
Sbjct  723  SDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGK  782

Query  785  VRGSITVNASASDDEIKAKAFEEPNVKKHMEGKALVKVIIVPKRMVNIVVK  835
            V++ + V    S +E++  A+ + +V+ ++ GK ++KVI VP+++VNIV+K
Sbjct  783  VKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

447) leuS in NC_018887


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  743 bits (2812),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 422/823 (52%), Positives = 605/823 (74%), Gaps = 15/823 (1%)

Query  1    MSKYEFIKIEKKWQEFWDNNKTYKVIEDPNIPKEKRLYILDMFPYPSANGLHVGHPEGYT  60
            M+ Y+   IE KWQ FW +N T+K   D++ PK   +Y LDMFPYPS+ GLHVGHPEGYT
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPK---FYALDMFPYPSGAGLHVGHPEGYT  57

Query  61   ATDIFARYKILNGFHVLHPIGFDSFGLPAENYAIQTGTHPKKSTEENINKFKKQIKALGF  120
            ATDI++R+K  +G +VLHP+G D+FGLPAE+YA++TG +P   T ENI +FK+QI+ALGF
Sbjct  58   ATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGF  117

Query  121  AYDWDREIRTHDENYYKWTQWIFLQLYKKGLAYAKEMPVWYCPELGTVLANEEIIQTPNG  180
            +YDWDRE+ T D NYYKWTQWIF +LY KGLAY  E+PV    ELGT +ANEE++  P+G
Sbjct  118  SYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVL--PDG  175

Query  181  PKSERGFHNVEKKYLRQWVLKITKYAERLLNDLEELEWPESVKEMQRNWIGKSTGVEIDF  240
              SERG   V +K +RQW+LKIT YAERLL+DLEE++WPES+K+MQRNWIGKSTG ++ F
Sbjct  176  T-SERGGYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTF  234

Query  241  EIEGYNDKIKVFTTRPDTIFGITYLVIAPENKLVEKITKDNFKSNVLKYIKQEELKSDLK  300
             + + +  + VFTTRPDT+FG TY V+APE+ LV+ IT  +    V  Y +Q  LKSDL 
Sbjct  235  KVKDTDKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLA  294

Query  301  RTSLEKDKSGVFTGSYAFHPITNVKIPIWVGSYVLGTYGSGAVMGVPAHDERDFQFAKKY  360
            RT L K+K+GV TGSYA++P+    +P+W++ YVL++YG+GA+M+VPAHDERD +FAK++
Sbjct  295  RTDLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQF  354

Query  361  KLKILPVISKSGKNEILEKAFINDGISINSPDEF-NNLKNSEVKDKVIKWLTKNKKGKET  419
            +L I+PV+  +   ++ E AF +DG+ INS  +F + L ++    K++ WL  +  G+E 
Sbjct  355  NLDIIPVLEGG---NVEEAAFTEDGLHINS--DFLDGLDKASAIAKMVEWLEAEGVGNEN  409

Query  420  VTYKLRDWVFSRQRYWGEPIPILFDKLGNAIPLEKNDLPLKLPETANYKPSGTGESPLSR  479
            VTY+LRDW+FSRQRYWGEPIPI+    G + ++  ++LPL LP T + +PSGTGESPL+ 
Sbjct  410  VTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLAN  469

Query  480  IKDWVNVKDTDFT---RETNTMPQWAGSCWYYLRYLDPKNSKKFANHKKIEYWMPVDLYI  536
            + DW++V   D     RETNTMPQWAGS WYYLRY+DP N+ K+A++  +  W+PVD+Y+
Sbjct  470  VTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYV  529

Query  537  GGAEHTVLHLLYSRFWHKVLYDLGHVNTKEPFKKLINQGIITAFSYQKENGVLIPNDQVI  596
            GGAEH+VLHLLY+RFWHKVLYDLG V TKEPF+KL+NQG+I + SY+   G L++ D+V 
Sbjct  530  GGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVE  589

Query  597  EkdnkffdkkdnkEVTQVIAKMSKSLKNVINPDDIIKEFGADSIRIYEMFMGPLTDSKPW  656
             +D  FF+     E+ Q  AKMSKSLKNV+NPDD++ ++GAD++R+YEMFMGPL  S +W
Sbjct  590  KRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAW  649

Query  657  NTKGIIGVFRFLNKIWNLREKELSKDNPPKEIMSQLHKVIKKVTEDTEKLNFNTAISAMM  716
            +  G+ G  +FL+++  L       ++ +  +    +  +K VTE+ ++++FNTAI+ +M
Sbjct  650  SEEGLEGSRKFLDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLM  709

Query  717  IFINELSKYEKNYLNIFKPFIIILSPYAPHLAEELWEYIGETPSLFKNSKWPKFDETLII  776
            +F+N  +K +K + +  K F+ +++P+APHL+EELW+ +  +   +    WP +DE+ ++
Sbjct  710  VFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLV  769

Query  777  KETKEIVLQINGKIKDKILLNKETDEEELKEIAMENSKIKSNL  819
             +  EIV+QI+GK+K K+++ K+   EEL+E+A+ N K+++++
Sbjct  770  ENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEI  812

448) leuS in NC_007512


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  742 bits (2807),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 443/843 (53%), Positives = 602/843 (72%), Gaps = 53/843 (6%)

Query  3    YDFSHTEKKWQAYWQEHGTFQAEEGQEKPKYYVLDMFPYPSGSGLHVGHLEGYTASDIVA  62
            YD +  E KWQA+W ++ TF++  +  KPK+Y LDMFPYPSG+GLHVGH EGYTA+DI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYRRSRGNNVLHPMGWDAFGLPAEQYAIKTGTHPSLTTENNIRSFRETLQAMGFSYDWSR  122
            R++R++G+NVLHPMGWDAFGLPAEQYA+ TG +P+  T +NI +F+  ++A+GFSYDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EINTTDPGYFRWTQWIFLKLYEMGLAYQSEVDVNWCVELRAVLANEEV---EEKIAEGLT  179
            E+NTTDP Y++WTQWIF KLYE GLAY++EV VNW  EL + +ANEEV         G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  180  VVRRPLRQWVLKITAYAERLLLDLDGLDWPENVKQMQRNWIGRSEGVEVDFELRCHRKML  239
            VVR+P+RQW+LKITAYAERLL DL+ +DWPE++K+MQRNWIG+S G +V F ++   K +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  240  RVYTTRPDTLFGATYLVISPEHPMAEKLATAPQLVEVKNYISKAKLKTELERTGLQKDKT  299
             V+TTRPDTLFGATY V++PEH++ + ++T+ Q   V +Y  +A LK++L RT+L K+KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  300  GVFTGSYAINPANGEALPVWISDFVLTSYGTGAIMSVPAHDSRDWEFAKKFGLPIVEVVK  359
            GV TGSYAINP NG  +PVWI+D+VL+SYGTGAIM+VPAHD RDWEFAK+F L I+ V+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  360  SPHDVQDAVYEGKDSTAVNSSNSEISLDGLAFPEAFERMASWLELKKCGERKVNYRLRDW  419
            + + V++A +   D+  +NS      LDGL  + A+ +M  WLE    G+ +V YRLRDW
Sbjct  364  GGN-VEEAAF-TEDGLHINSD----FLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDW  417

Query  420  IFSRQRYWGEPIPVKHYEDGSLGT--ETDLPLRLPEVEAYQPTETGESPLANIPEWLYGT  477
            +FSRQRYWGEPIP+ H EDG+  +  E++LPL LP     +P+ TGESPLAN+ +WL  T
Sbjct  418  LFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT  477

Query  478  DGKGA-FRRETNTMPQWAGSCWYYLRFIDPRNSEHLVDAEKEHYWMNVDLYIGGAEHAVL  536
               G   RRETNTMPQWAGS WYYLR+IDP+N+E L D E    W+ VD+Y+GGAEHAVL
Sbjct  478  REDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVL  537

Query  537  HLLYARFWHKVLYDLKVVSTKEPFQKLFNQGMILG-------------------------  571
            HLLYARFWHKVLYDL VV+TKEPFQKLFNQGMILG                         
Sbjct  538  HLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFH  597

Query  572  --------EDGEKMSKSRGNVIPADHVLEKYGADAVRLYEMFLGPLEQVKPWNTNGIEGV  623
                    +   KMSKS  NV+ +D+V+E+YGAD++R+YEMF+GPL+   +W+ +G+EG 
Sbjct  598  VETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGS  657

Query  624  SRFLNRVWRLVHPDTEGPAAVLDEAAMPGELLRRMHKTVKKVREDTECLKFNTAIAEMMV  683
             +FL+RV RL+         + +E +  G L +  + TVK V E+ + +KFNTAIA++MV
Sbjct  658  RKFLDRVYRLI-----TTKEITEENS--GALDKVYNETVKAVTEQVDQMKFNTAIAQLMV  710

Query  684  FVNDLHRTGNRNREAIETLVLLLAPYAPHISEELWEAL-GHPESIARAPFPTFDPALAAN  742
            FVN  ++ ++   +    +V L+AP+APH++EELW+AL +  ESI+  P P++D +   +
Sbjct  711  FVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVE  770

Query  743  DVLTIAVQVNGKLRGTFEAAKDASKEEMLEAARAVESVRKFIEGSTVVKEIVVPGKLINF  802
            + + I VQ++GK+++ +  AKD S+EE+ E A A E V+  I G  ++K I VP KL+N+
Sbjct  771  NDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNI  830

Query  803  AVK  805
             +K
Sbjct  831  VIK  833

449) leuS in NC_010831


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  742 bits (2809),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 442/842 (53%), Positives = 602/842 (72%), Gaps = 52/842 (6%)

Query  3    YDFQSIEKKWQAYWNEHQTFLTKETVDKPKYYVLDMFPYPSGSGLHVGHLEGYTATDIIS  62
            YD  +IE KWQA+W +++TF T     KPK+Y LDMFPYPSG+GLHVGH EGYTATDI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRSRGHNVLHPMGWDAFGLPAEQFAIKTGTHPKVITEKNVSSFKDTLMRMGFSYDWNR  122
            R+KR++GHNVLHPMGWDAFGLPAEQ+A+ TG +P  +T  N+++FK  +  +GFSYDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EINTTDPGYYAWTQWIFLQLLDRGLAYTSEIDVNWCEELKTVLANEEV---AEKVADGHA  179
            E+NTTDP YY WTQWIF +L ++GLAY +E+ VNW EEL T +ANEEV   +    +G +
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  180  VVRKPLRQWVLKITAYAERLLSDLDLVDWPESVKQMQRNWIGRSEGVEIDFQLPCHRTSL  239
            VVRKP+RQW+LKITAYAERLL DL+ VDWPES+K+MQRNWIG+S G ++ F++      +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  240  KVYTTRPDTLFGATYLVISPEHPMAEKLATAEHLIEAKNYIEEAKRKTELERTGLQKEKT  299
             V+TTRPDTLFGATY V++PEH++ + ++T+++     +Y  +A  K++L RT+L KEKT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  300  GVFTGSFAVNPANGQALPVWISDFVLTSYGTGAIMSVPAHDGRDWEFAKKFDLPIVEVIK  359
            GV TGS+A+NP NG+ +PVWI+D+VL+SYGTGAIM+VPAHD RDWEFAK+F+L I+ V+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  360  SPHDVEEAVFEEKGSVCINSSNDDISLDGLPFETSFGVMADWLEKKGTGKRTVKYKLRDW  419
            + + VEEA F E G + INS      LDGL   ++++ M +WLE  G G+  V Y+LRDW
Sbjct  364  GGN-VEEAAFTEDG-LHINSD----FLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDW  417

Query  420  IFSRQRYWGEPIPVKYYEDGTLR--PESDLPLTLPDIEAYEPTTTGESPLANISEWLYGT  477
            +FSRQRYWGEPIP+   EDGT    PES+LPL LP      P+ TGESPLAN+++WL  T
Sbjct  418  LFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT  477

Query  478  DENG-SFRRETNTMPQWAGSCWYYLRFIDPGNTEKPVDPKKEQYWMNVDLYVGGAEHAVL  536
             E+G   RRETNTMPQWAGS WYYLR+IDP NTEK  D    + W+ VD+YVGGAEHAVL
Sbjct  478  REDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVL  537

Query  537  HLLYARFWHKVLFDLGVVSTKEPFQKLFNQGMILG-------------------------  571
            HLLYARFWHKVL+DLGVV+TKEPFQKLFNQGMILG                         
Sbjct  538  HLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFH  597

Query  572  --------EDNEKMSKSRGNVIPADQVLGSYGADAVRLYEMFLGPLEQVKPWNTNGIEGV  623
                    +   KMSKS  NV+ +D+V+  YGAD++R+YEMF+GPL+   +W+ +G+EG 
Sbjct  598  VETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGS  657

Query  624  SRFLSRVWRLIYPEPGSMAELNEAPLTEDLTRTMHKAVKKITDHTEQLKFNTAISEMMVF  683
             +FL RV RLI     +  E+ E   +  L +  + +VK +T++ +Q+KFNTAI+++MVF
Sbjct  658  RKFLDRVYRLI-----TTKEITEEN-SGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVF  711

Query  684  VNELHKSGSRNRTAVETLLLLLSPYAPHICEELWEAI-GHDTSITEENWPLFDPALAADN  742
            VN  +K +         ++ L++P+APH+ EELW+A+ + + SI+   WP +D +   +N
Sbjct  712  VNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVEN  771

Query  743  EVTIAVQVNGKLRGTVTAPAGSPKNILLDSARKEESVRKFLDGMSIIKEVVVPDRLVNFV  802
            +V I VQ++GK+++ +  + + +++ L + A  +E V+  + G  IIK + VP++LVN+V
Sbjct  772  DVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIV  831

Query  803  VK  804
            +K
Sbjct  832  IK  833

450) leuS in NC_015713


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  742 bits (2806),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 452/860 (53%), Positives = 616/860 (72%), Gaps = 36/860 (4%)

Query  6    YNHIEVERKWQTYWKENQLFKAKVDPSKPKYYILDMFPYPSGAGLHVGHVTGYTATDILA  65
            Y+H  +E KWQ++W +N+ FK+  D+SKPK+Y LDMFPYPSGAGLHVGH  GYTATDIL+
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  66   RYKRQKGYNVLHPMGWDSFGLQAEQYAVRTGTHPKITTEKNINTYRRQLQSLGFSYDWDR  125
            R+KR +G NVLHPMGWD+FGL AEQYA+ TG +P   T  NI  ++RQ+++LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  126  EFATSDPDYYKWTQWIFSKLYEQGLAYEAEILVNYCPALGTVLANEEV-ENGKSREGGYP  184
            E  T+DP+YYKWTQWIF+KLYE+GLAYEAE+ VN    LGT +ANEEV  +G S  GGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  185  VERRPLRQWILKITAYAERLLADLETLDWPEYLKILQRNWIGKSEGAEVVFLENESKQPI  244
            V R+P+RQW+LKITAYAERLL DLE +DWPE +K +QRNWIGKS GA+V F  +++ + +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  245  TVFTTRHDTLFGTTFLVLSPEHPLVNKITTDDQKEDVEAYQQKTTAKSDMERTDLNKEKS  304
            TVFTTR DTLFG+T+ VL+PEH+LV+ ITT DQ E V  Y+++++ KSD+ RTDL KEK+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  305  GVWTGAYARNPINNELIPIWIADYVLMGYGTGAVMAVPGGDERDFEFAKKFGLKIIppyd  364
            GVWTG+YA NP+N   +P+WIADYVL +YGTGA+MAVP+ DERD EFAK+F L II    
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDII----  359

Query  365  pllkdylddlpADMAEEDFRLEILAGNRCWTKGGVVINGKSELFDINGLEIEAAKNKVAD  424
                       +++ E  F           T +G+ IN+    F ++GL+  +A  K+ +
Sbjct  360  ------PVLEGGNVEEAAF-----------TEDGLHINSD---F-LDGLDKASAIAKMVE  398

Query  425  WLETHKCGRRTTTYKLRDWLFSRQRYWGEPFPILHLEDGTKRlldldelplvlpelTDYK  484
            WLE++  G    TY+LRDWLFSRQRYWGEP+PI+H EDGT   +   ELPLVLP   D +
Sbjct  399  WLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIR  458

Query  485  PQGEGRTPLENVPEWVEITDPKTGKKALRETNTMPQWAGSCWYYLRFCDPHNENAAWGEK  544
            P G G +PL NV +W+E+T    G K+ RETNTMPQWAGS WYYLR+ DPHN +   +E 
Sbjct  459  PSGTGESPLANVTDWLEVT-REDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEE  517

Query  545  EEKYWMPVDMYVGGVEHAVLHLLYARFWHKVLYDLDLVSTTEPFQTLRNQGLVTARAFKR  604
              K W+PVD+YVGG EHAVLHLLYARFWHKVLYDL++V+T EPFQ L NQG++ + +++ 
Sbjct  518  LLKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRD  577

Query  605  LGGGYVDAHHVMKKGDEYFEEGGDEKLLSLVEKMSKSKLNGVTPDEIVQELGADSLRLYE  664
              G+ V ++ V K+++ +F+   +E L     KMSKS  N V PD++V++ GAD+LR+YE
Sbjct  578  SRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYE  637

Query  665  MFMGPFDKEKLWNSEAISGCRRFLDRFFQLVTSDKVIGKEEGEGMKLAHILVKGVENDIE  724
            MFMGP+D    W+ E++ G R+FLDR ++L+T+  +   + G   K+ +  VK+V ++++
Sbjct  638  MFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVD  697

Query  725  SMLYNTAISKMMEFVNAFVK----LDSYPKKALQMAVQALSPFAPHLAEECWEILGKEPG  780
             M +NTAI+++M FVNA  K    +  Y+K  +Q+    ++PFAPHL+EE W+ L     
Sbjct  698  QMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQL----IAPFAPHLGEELWQALTASGE  753

Query  781  SLTFEPYPQADPKYLEEASAVYVVQINGKFRGKWELPKGQSQDELLEFVKGEEKIAKHLQ  840
            S+++ P P  D   L E     VVQI+GK ++K  ++K+ S++EL E   ++EK+  ++ 
Sbjct  754  SISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIA  813

Query  841  G-EIMKVIFVPDKLINLVVK  859
            G +I+KVI VP+KL+N+V+K
Sbjct  814  GKDIIKVIAVPNKLVNIVIK  833

451) leuS in NC_017238


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  740 bits (2801),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 419/823 (51%), Positives = 604/823 (74%), Gaps = 15/823 (1%)

Query  1    MSKYEFIKIEKKWQEFWDNNKTYKVIEDPNIPKEKRLYILDMFPYPSANGLHVGHPEGYT  60
            M+ Y+   IE KWQ FW +N T+K   D++ PK   +Y LDMFPYPS+ GLHVGHPEGYT
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPK---FYALDMFPYPSGAGLHVGHPEGYT  57

Query  61   ATDIFARYKILNGFHVLHPIGFDSFGLPAENYAIQTGTHPKKSTEENINKFKKQIKALGF  120
            ATDI++R+K  +G +VLHP+G D+FGLPAE+YA++TG +P   T ENI +FK+QI+ALGF
Sbjct  58   ATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGF  117

Query  121  AYDWDREIRTHDENYYKWTQWIFLQLYKKGLAYAKEMPVWYCPELGTVLANEEIIQTPNG  180
            +YDWDRE+ T D NYYKWTQWIF +LY KGLAY  E+PV    ELGT +ANEE++  P+G
Sbjct  118  SYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVL--PDG  175

Query  181  PKSERGFHNVEKKYLRQWVLKITKYAERLLNDLEELEWPESVKEMQRNWIGKSTGVEIDF  240
              SERG   V +K +RQW+LKIT YAERLL+DLEE++WPES+K+MQRNWIGKSTG ++ F
Sbjct  176  T-SERGGYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTF  234

Query  241  EIEGYNDKIKVFTTRPDTIFGITYLVIAPENKLVEKITKDNFKSNVLKYIKQEELKSDLK  300
             + + +  + VFTTRPDT+FG TY V+APE+ LV+ IT  +    V  Y +Q  LKSDL 
Sbjct  235  KVKDTDKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLA  294

Query  301  RTSLEKDKSGVFTGSYAFHPITNVKIPIWVGSYVLGTYGSGAVMGVPAHDERDFQFAKKY  360
            RT L K+K+GV TGSYA++P+    +P+W++ YVL++YG+GA+M+VPAHDERD +FAK++
Sbjct  295  RTDLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQF  354

Query  361  KLKILPVISKSGKNEILEKAFINDGISINSPDEF-NNLKNSEVKDKVIKWLTKNKKGKET  419
            +L I+PV+  +   ++ E AF +DG+ INS  +F + L ++    K++ WL  +  G+E 
Sbjct  355  NLDIIPVLEGG---NVEEAAFTEDGLHINS--DFLDGLDKASAIAKMVEWLEAEGVGNEN  409

Query  420  VTYKLRDWVFSRQRYWGEPIPILFDKLGNAIPLEKNDLPLKLPETANYKPSGTGESPLSR  479
            VTY+LRDW+FSRQRYWGEPIPI+    G + ++  ++LPL LP T + +PSGTGESPL+ 
Sbjct  410  VTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLAN  469

Query  480  IKNWVNVKDTDFT---RETNTMPQWAGSCWYYLRYLDPKNSKEFANHKKIEYWMPVDLYI  536
            + +W++V   D     RETNTMPQWAGS WYYLRY+DP N+  +A++  +  W+PVD+Y+
Sbjct  470  VTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYV  529

Query  537  GGAEHTVLHLLYSRFWHKVLYDLGHVNTKEPFKKLINQGIITAFSYQKENGVLIPNDQVI  596
            GGAEH+VLHLLY+RFWHKVLYDLG V TKEPF+KL+NQG+I + SY+   G L++ D+V 
Sbjct  530  GGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVE  589

Query  597  EkdnkffdkkdnkEVTQVIAKMSKSLKNVINPDGIIKEFGADSIRIYEMFMGPLTDSKPW  656
             +D  FF+     E+ Q  AKMSKSLKNV+NPD+++ ++GAD++R+YEMFMGPL  S +W
Sbjct  590  KRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAW  649

Query  657  NTKGIIGVFRFLNKIWNLREKELSKDNPPKEIMSQLHKVIKKVTEDTEKLNFNTAISAMM  716
            +  G+ G  +FL+++  L       ++ +  +    +  +K VTE+ ++++FNTAI+ +M
Sbjct  650  SEEGLEGSRKFLDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLM  709

Query  717  IFINELSKYEKNYLNIFKPFIIILSPYAPHLAEELWEYIGETPSLFKNSKWPKFDETLII  776
            +F+N  +K +K + +  K F+ +++P+APHL+EELW+ +  +   +    WP +DE+ ++
Sbjct  710  VFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLV  769

Query  777  KETKEIVLQINGKIKDKILLNKETDEEELKEIAMENSKIKSNL  819
             +  EIV+QI+GK+K K+++ K+   EEL+E+A+ N K+++++
Sbjct  770  ENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEI  812

452) Rleg_2339 in NC_012850


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  739 bits (2795),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 447/838 (54%), Positives = 606/838 (73%), Gaps = 14/838 (1%)

Query  3    YDPKTIEPKWQAYWADHHIFRAEIDPARPKFYALDMFPYPSGAGLHVGHPLGYTATDITC  62
            YD  +IEPKWQA+WAD+H F++  D+++PKFYALDMFPYPSGAGLHVGHP GYTATDI  
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRMRGFNVLHPMGWDSFGLPAERHAMRTGVHPDITTKRNIETFRGQVQRLGFSYDWSR  122
            R+KR +G NVLHPMGWD+FGLPAE+ AM TG +P   T  NI  F+ Q++ LGFSYDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EFATTDPAYVRWTQWIFLKLFEKGLAYQEEIAVNWCPAQNAVLADEEV-KDGRYVETGDP  181
            E  TTDP Y +WTQWIF KL+EKGLAY+ E++VNW     + +A+EEV  DG     G P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VIRRRMRQWMLRITAYADRLLQGLDGLDWPENLKTMQRNWIGRSEGAEIRFPLEHGKKVI  241
            V+R+ MRQWML+ITAYA+RLL++L+ +DWPE++K MQRNWIG+S GA++ F + +  K +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  TVFTTRPETLFGASYMVLAPEHPAVAAIIEPEMREAVAAYIAEAEGLEETVRADGRREKT  301
            TVFTTRP+TLFGA+Y VLAPEH+ V AI  ++  EAVA Y  +A    +  R+D  +EKT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYATNPANGARLPVWVADYVLAGYGTGALMAVPAHDARDYAFAHAHELPIIRVVD  361
            GV TG+YA NP NG  +PVW+ADYVLA+YGTGA+MAVPAHD RD  FA   +L II V++
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  SEDDIEKVAYEGEGAMVNSGFLDGLGSPEARSAIIAWLQANGAGWPKVMYRLRDWLFSRQ  421
            + +++E  A+  +G  +NS+FLDGL+ + A + ++ WL+A+G G  +V YRLRDWLFSRQ
Sbjct  364  G-GNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQ  422

Query  422  RYWGEPIPVLHLADGSVMplpeeclpllppelDDYAPAPDGEPPLARAQAWVETIVPGTD  481
            RYWGEPIP++H  DG+  ++PE  LPL+ P   D  P+  GE+PLA    W+E +    +
Sbjct  423  RYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE-VTREDG  481

Query  482  IPARRETNTMPQWAGSCWYYLRFLDPENTSEPVGREAERYWMPVDLYVGGAEHAVLHLLY  541
            + +RRETNTMPQWAGS WYYLR++DP+NT    + E  + W+PVD+YVGGAEHAVLHLLY
Sbjct  482  VKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLY  541

Query  542  ARFWHKVLYDIGVVSTEEPFQRLFNQGMILAHSYRDAAGRYYAPSFVVEEEGRW--LAGS  599
            ARFWHKVLYD+GVV+T EPFQ+LFNQGMIL+ SYRD+ G   A   V   +G    +  +
Sbjct  542  ARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETG  601

Query  600  VEMQRAVEKMSKSRLNVVNPDDVVHQFGADALRLYEMFMGPLDAAKPWQTAGVIGVRRFL  659
             E+++A  KMSKS  NVVNPDDVV+Q+GAD+LR+YEMFMGPLDA+ +W   G+ G R+FL
Sbjct  602  EELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFL  661

Query  660  ERAWRIVCDESDGLSAAVLEAASSPQLLRLRHQTVKAVTADIEAIRFNTAVSRLMELANA  719
            +R  R++           +   +S  L ++ ++TVKAVT +++ ++FNTA+++LM + NA
Sbjct  662  DRVYRLITTKE-------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNA  714

Query  720  LTAEAVRPREVVETLVLLLAPFAPHIAEELWSKL-GHGETLTWVSWPTFDPAMVGMETRE  778
               E     +    +V L+APFAPH++EELW  L + GE+++ V+WP++D + +  +  E
Sbjct  715  ANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVE  774

Query  779  YVVQINGKVRHRFEaaadlgeallaaaR-SEPSIMALLDGKTVVKEILVPGRLVNFVV  835
             VVQI+GKV+ ++  A DL+   L     ++  + A + GK ++K I VP +LVN+V+
Sbjct  775  IVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

453) leuS in NC_011059


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  739 bits (2796),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 440/842 (53%), Positives = 614/842 (73%), Gaps = 52/842 (6%)

Query  3    YEFSTIEQKWQKYWADNQTFLTDDNPDKPKYYVLDMFPYPSGTGLHVGHLEGYTATDIIA  62
            Y+ ++IE KWQ +WADN+TF T+ ++ KPK+Y LDMFPYPSG+GLHVGH EGYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRSRGFNVLHPMGWDAFGLPAEQFAIKtgthpttttQKNVSSFRQTLQNMGFSYDWSR  122
            R+KR++G NVLHPMGWDAFGLPAEQ+A+ TG +P+  T  N+++F++ ++ +GFSYDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EINTTDPNYFRWTQWIFLQLLDKGLAYMSEVDVNWCEDLRVVLANEEV---DEKIAAGHT  179
            E+NTTDPNY++WTQWIF +L +KGLAY +EV VNW E+L   +ANEEV   +    +G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  180  VVRKPLRQWVLKITAYAERLLGDLDELDWPENVKQMQRNWIGRSEGVEIDFELPCHRQKL  239
            VVRKP+RQW+LKITAYAERLL DL+E+DWPE++K+MQRNWIG+S G ++ F +    + +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  240  TVYTTRPDTLFGASYLVISPEHPLAEKLATAPQLVELKNYIREAKLKTELERTGLQKEKT  299
            TV+TTRPDTLFGA+Y V++PEH+L + ++T+ Q   + +Y R+A LK++L RT+L KEKT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  300  GVFTGSYAINPANGEALPVWVSDFVLTSYGTGAIMSVPAHDSRDWEFAKKFGLPIIEVIQ  359
            GV TGSYAINP NG  +PVW++D+VL+SYGTGAIM+VPAHD RDWEFAK+F L II V++
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  360  SPHDVQDEVFEGKESICVNSSNNEISLDGLDFTSAFKRMADWIESSGKGRRKINYKLRDW  419
            + + V++  F   +++ +NS      LDGLD +SA+ +M +W+E+ G G  ++ Y+LRDW
Sbjct  364  GGN-VEEAAF-TEDGLHINSD----FLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDW  417

Query  420  IFSRQRYWGEPIPVKHYDDGSLR--PETDLPLTLPEVEAYHPSTTGESPLANIEDWL-FG  476
            +FSRQRYWGEPIP+ H +DG+    PE++LPL LP     +PS TGESPLAN+ DWL   
Sbjct  418  LFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT  477

Query  477  QDEHGAFRRETNTMPQWAGSCWYYLRFIDPSNQQQLVDPDKERYWMNVDLYIGGAEHAVL  536
            +++    RRETNTMPQWAGS WYYLR+IDP N ++L D +  + W+ VD+Y+GGAEHAVL
Sbjct  478  REDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVL  537

Query  537  HLLYARFWHKVLYDLGVVSTKEPFQKLFNQGMILG-------------------------  571
            HLLYARFWHKVLYDLGVV+TKEPFQKLFNQGMILG                         
Sbjct  538  HLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFH  597

Query  572  --------EDNEKMSKSRGNVIPADHVMQSYGADAVRLYEMFLGPLEQVKPWNTNGIEGI  623
                    +   KMSKS  NV+ +D+V++ YGAD++R+YEMF+GPL+   +W+ +G+EG 
Sbjct  598  VETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGS  657

Query  624  SRFLSRVWRIVYPEQEGPAMLTDTPLDDALTRRMHKTIKKVTEDTEHLKFNTAIAEMMVF  683
             +FL RV R++   +     +T+    +AL +  + T+K VTE+ +++KFNTAIA++MVF
Sbjct  658  RKFLDRVYRLITTKE-----ITEEN-SGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVF  711

Query  684  VNELHKAGCRNRKALETlllllAPYAPHICEELWQA-AGNNEPIARAPFPVFDPALAEDN  742
            VN  +K +         ++ L+AP+APH+ EELWQA +++ E+I+  P P +D +   +N
Sbjct  712  VNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVEN  771

Query  743  ELTIAVQVNGKLRGTFLAPAGLSKEAMIAGAREIESVKKFLEGMTIIKEIAVPGKLVNFA  802
            ++ I VQ++GK+++ ++ + +LS+E +   A   E V+  + G  IIK IAVP KLVN+ 
Sbjct  772  DVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIV  831

Query  803  VK  804
            +K
Sbjct  832  IK  833

454) leuS in NC_021833


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  738 bits (2793),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 465/840 (56%), Positives = 615/840 (74%), Gaps = 47/840 (5%)

Query  3    FSHKAIEKKWQKFWEENNTFKTTSDKDK-KAYILDMFPYPSGAGLHVGHPKGYTATDVFA  61
            + H AIE KWQ FW +N+TFKT +D  K K Y LDMFPYPSGAGLHVGHP GYTATD+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  62   RMRRMQQYDVLHPIGWDAFGLPAEQYALKTGNDPREFTAKNIITFRNQLKKLGFSYDYNK  121
            R +R Q  +VLHP+GWDAFGLPAEQYA+ TGNDP EFTA NI  F+ Q++ LGFSYD ++
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  122  EVNTSDPNYYKITQWIFQQLYKKGLAEIREANVNWCEGLGTVLANEEVILENGKMVSEVG  181
            EVNT+DPNYYK TQWIF +LY KGLA   E  VNW E LGT +ANEEV+ +     SE G
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDG---TSERG  180

Query  182  GFEVIKKPMKQWVLKITKYADRLLEGLDDLDWPSSVKELQKNWIGKSEGVILNFDVKDIN  241
            G+ V++KPM+QW+LKIT YA+RLLE+L+++DWP S+K++Q+NWIGKS G  + F VKD +
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  242  EKVEVFTTRADTIFGVSYVVLAPENNLVLKLTTDENKQKVEEYISLTKTKTDVERQDDSK  301
                VFTTR+DT+FG +Y VLAPE+ LV  +TT ++ + V +Y   +  K+D+ R D +K
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  302  EKTGVFTGSYVINPITNELLPVWTADYVLNDYATGAVMAVPAHDERDWKFAKKYELPIKY  361
            EKTGV TGSY INP+    +PVW ADYVL  Y+TGA+MAVPAHDERDW FAK+++L I  
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  362  VLETKD-ESKAFVGESTLINSDFLNGLNRFEAInlvveklkkenkakkQINYKLRDWLFS  420
            VLE  + E  AF  ++  INSDFL+GL++  AI  +VE L  E  ++ ++ Y+LRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  421  RQRFYGEPFPIIFLEDGQIALIDEKDLPLELPKTDYIKPSGTGESPLANLTDWVNIEF-N  479
            RQR+ GEP+PII  EDG  + + E +LPL LP T  I+PSGTGESPLAN+TDW+++   +
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  480  GQKAKRETNTMPQWAGSCWYYLAYILTTSPNNLVDINSQEAMELFKKWLPVDLYIGGQEH  539
            G K++RETNTMPQWAGS WYYL YI   + ++L D       EL+K+WLPVD+Y+GG EH
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADE------ELLKQWLPVDIYVGGAEH  534

Query  540  AVLHLLYARFWHQVLFDLKIVPTKEPFQKLINQGMILA----------------------  577
            AVLHLLYARFWH+VL+DL +VPTKEPFQKL+NQGMIL+                      
Sbjct  535  AVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGS  594

Query  578  ----DNGE-------KMSKSKGNVINPDDIIESHGADTLRLYEVFMGPLEASLPWSFKGL  626
                + GE       KMSKS  NV+NPDD++E  GADTLR+YE+FMGPL+AS++WS  GL
Sbjct  595  FFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGL  654

Query  627  DGARKWLDRVYRMIENIELTDQNNGNLDFIYNDVVKKVTQMIEDCKFNTAVSQLMMFVNA  686
            +G+RK LDRVYR+I   E+T++N+G LD +YN+ VK VT+ +++ KFNTA++QLM+FVNA
Sbjct  655  EGSRKFLDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNA  714

Query  687  VYKEEKPVYKVYILNFIKMLSIFTPHLAEELWFK-TGNKETVCLQIWPVHDESKLSLSTV  745
              KE+K ++  Y   F+++++ F+PHL+EELW   T++ E++    WP  DESKL  + V
Sbjct  715  ANKEDK-LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDV  773

Query  746  VIAVQINGKLRGTFEVDKGTDKEELISLAKKLDNikeqiegkqiikeiAVLDKIVNIVIK  805
             I VQI+GK+++ + V K+  +EEL  +A   ++++ +I GK+IIK IAV +K+VNIVIK
Sbjct  774  EIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

455) leuS in NC_014355


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  736 bits (2784),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 467/845 (56%), Positives = 618/845 (74%), Gaps = 54/845 (6%)

Query  5    YDHQALESKWQTYWETHRPFRALDDQSKPKFYCLDMFPYPSGSGLHVGHLEGYTATDIVS  64
            YDH A+E+KWQ++W  ++ F++  D SKPKFY LDMFPYPSG+GLHVGH EGYTATDI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  65   RYKRMRGFNVLHPMGWDAFGLPAEQYAVKTGVHPAITTAQNIATFKRQMKRVGLSYDWER  124
            R+KR +G NVLHPMGWDAFGLPAEQYA+ TG +PA  TA+NIA FKRQ++ +G+SYDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  125  ELSTTDQDYYRWTQWIFLKLFERGLAYVAEVPVNWCPALGTVLANEEIV-DGKSEVGGFD  183
            E++TTD +YY+WTQWIF KL+E+GLAY AEVPVNW   LGT +ANEE++ DG SE GG+ 
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  184  VIRKPMRQWVLKITAYAERLLEDLTLVEWPTSTLEMQKNWIGRSIGAEVDFPLADQRGNL  243
            V+RKPMRQW+LKITAYAERLLEDL  V+WP S  +MQ+NWIG+S GA+V F + D   ++
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  244  RVFTTRPDTLFGATYMVLAPEHPLVDVVTTPEQREQVTAYREAASRKSDLQRQELDKVKT  303
             VFTTRPDTLFGATY VLAPEH+LVD +TT++Q E V+ Y+  AS KSDL R +L K KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  304  GVFTGGYAVNPVNQERLPIWIADYVLMSYGTGAIMAVPAHDERDWAFATQYRLPIREVIQ  363
            GV TG+YA+NPVN   +P+WIADYVL SYGTGAIMAVPAHDERDW FA Q+ L I  V++
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  364  GGQVEKAAFVETDRGRVVNSTTPDGSCSLDGLLPSDAIPTMTAWLETKGRGKKTINYKLR  423
            GG+VE AAF  T+ G  +NS        LDGL  + AI+ M  WLE+ G G+  + Y+LR
Sbjct  364  GGNVEEAAF--TEDGLHINSD------FLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  424  DWLFARQRYWGEPFPIV-WVDGeprplpeeqlplplpeTKNFKPSGSGESPLANLHDWLE  482
            DWLF+RQRYWGEP+PI+ W DG + ++PE +LPL LP TK+++PSG+GESPLAN+ DWLE
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  483  TTDPATGKPARRETNTMPQWAGSCWYYLRFIDPKNPAQVVDPAKERYWMPVDLYIGGSEH  542
             T     K +RRETNTMPQWAGS WYYLR+IDP N  ++ D    + W+PVD+Y+GG+EH
Sbjct  476  VTREDGVK-GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEH  534

Query  543  AVLHLLYSRFWHKVLFDAGVVSTPEPFKKLVHQGIVLG----------------------  580
            AVLHLLY+RFWHKVL+D GVV+T EPF+KL +QG++LG                      
Sbjct  535  AVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGS  594

Query  581  -----------EDNQKMSKSRGNVVNPDEMIDQFGADAVRLYEMFMGPLESMKPWSTRGV  629
                       +   KMSKS  NVVNPD++++Q+GAD++R+YEMFMGPL++  +WS  G+
Sbjct  595  FFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGL  654

Query  630  EGITRFLDRVWRLLIGDEGALSPAVTDAEPSPEQLRLLHYTIKKVTDDIDALRFNTAISQ  689
            EG  +FLDRV RL+   E      +T+ ++++ + ++ + T+K VT+++D ++FNTAI+Q
Sbjct  655  EGSRKFLDRVYRLITTKE------ITEENSGALD-KVYNETVKAVTEQVDQMKFNTAIAQ  707

Query  690  MMVFTNEMTKLEQrprrllepfvllllpfaphlSEELWERLGQQPSAGQ-QPWPQFDPAL  748
            +MVF N   K ++        FV L+ PFAPHL+EELW+ L     +    PWP +D + 
Sbjct  708  LMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESK  767

Query  749  VVSDRLTIPIQVNGKLRGKLEVDAGASRELLE--PLAKKEVAEWLQGKEPKKVIYVEKKL  806
            +V + + I +Q++GK+++KL V  + SRE L+  +LA+  V   + GK+  KVI V +KL
Sbjct  768  LVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKL  827

Query  807  INFVV  811
            +N+V+
Sbjct  828  VNIVI  832

456) leuS in NC_015577


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  736 bits (2784),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 458/856 (54%), Positives = 595/856 (70%), Gaps = 58/856 (6%)

Query  1    MAKYPFETIEPKWQKFWADHKTFKAVEDPGFAQDKRRYVLDMFPYPSAQGLHVGHPEGYT  60
            M+ Y   +IEPKWQ FWAD+ TFK+  D++     + Y LDMFPYPS+ GLHVGHPEGYT
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDAS---KPKFYALDMFPYPSGAGLHVGHPEGYT  57

Query  61   ATDIYCRFLRMKGFNVLHPMGFDAFGLPAENYAIKTGTHPAITTAANINHFRTQIKSLGF  120
            ATDI  RF R +G NVLHPMG DAFGLPAE+YA+ TG +PA  TA NI +F+ QI++LGF
Sbjct  58   ATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGF  117

Query  121  SYDWDREVDTSQEDYYKWTQWIFLKLFEKGLAYEAESPINFCPSCKTGLANEEV-KDGLC  179
            SYDWDREV+T++ +YYKWTQWIF KL+EKGLAYEAE P+N      T++ANEEV  DG  
Sbjct  118  SYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTS  177

Query  180  ERCGTKVTRKRIRQWILKITAYAERLLEDLDGLDWPEPVKLMQRNWIGRSEGANVIFKID  239
            ER G  V RK +RQW+LKITAYAERLLEDL+ +DWPE++K MQRNWIG+S GANV FK+ 
Sbjct  178  ERGGYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVK  237

Query  240  GYPDTLEIYTTRPDTLFGATYMVLSPEHPLVGKITTAGQQDAVKAYVDSAAKKSDLERTD  299
            +    + ++TTRPDTLFGATY VL+PEH+LV+ ITT++Q +AV  Y   A+ KSDL RTD
Sbjct  238  DTDKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTD  297

Query  300  LAKEKTGVFSGAYAVNPVNNKKIPIWIADYVLISYGTGAIMAVPAHDERDWDFAKVYKLP  359
            LAKEKTGV +G+YA+NPVN K +P+WIADYVL SYGTGAIMAVPAHDERDW+FAK ++L 
Sbjct  298  LAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLD  357

Query  360  IIQVVSPTKPGSSEDVSREPAECTVADGFSVNSGSFDGLPTDEAKAKVTAWIEEQGIGKK  419
            II V+   +   +             DG+ +NS+ +DGL    A AK+  W+E +G+G+ 
Sbjct  358  IIPVLEGGNVEEA---------AFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNE  408

Query  420  AINYKLRDWIFSRQRYWGEPIPLVHCEKCGIVAVPEKDLPLKLPEVTSYAPTGTGESPLA  479
             + Y+LRDW+FSRQRYWGEPIP++H E     AVPE +LPL LP      P+GTGESPLA
Sbjct  409  NVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLA  468

Query  480  LISDWVNTSCPKCGGKAKRETNTMPQWAGSCWYYLRYLDPHNDKAFAAKDKVEYWAPVDL  539
             ++DW++ +    G K++RETNTMPQWAGS WYYLRY+DPHN   +A  + +  W PVD+
Sbjct  469  NVTDWLEVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDI  527

Query  540  YVGGVEHAVLHLLYSRFWHKVLYDLGLVNTKEPFQRLVNQGMILG---------------  584
            YVGG EHAVLHLLY+RFWHKVLYDLG+V TKEPFQ+L NQGMILG               
Sbjct  528  YVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDK  587

Query  585  ------------------EDNQKMSKSRGNVINPDDIVKEFGADSMRMYEMFMGPLEVTK  626
                              +   KMSKS  NV+NPDD+V ++GAD++R+YEMFMGPL+ + 
Sbjct  588  VEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASI  647

Query  627  PWLTAGLVGVSRFLERLWSIAEKCHLAEPNGTVIEAPDASHADLTRLLHKTIKKVGQDTD  686
            +W   GL G  +FL+R+       +L     T  E  + + + L ++ + T+K V ++ D
Sbjct  648  AWSEEGLEGSRKFLDRV------YRLI----TTKEITEENSGALDKVYNETVKAVTEQVD  697

Query  687  TLNFNTAISQMMIYSNELAKLAEVPRSLWEPLVQMIAPYAPHLGEELWERL-GHKESISK  745
             ++FNTAI+Q+M++ N   K   +       +VQ+IAP+APHLGEELW+ L +  ESIS 
Sbjct  698  QMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISY  757

Query  746  TQWPVYDEKLCVESEATIVVQVNGKIRDKFTAPVGtakaelektalalPGTVKWTDGLTV  805
              WP YDE   VE++  IVVQ++GK++ K+  + + ++ EL+  ALA         G  +
Sbjct  758  VPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDI  817

Query  806  VKVITVQDKLVNIVAK  821
            +KVI+V +KLVNIV K
Sbjct  818  IKVIAVPNKLVNIVIK  833

457) Trebr_1433 in NC_015500


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  736 bits (2784),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 456/863 (53%), Positives = 607/863 (71%), Gaps = 60/863 (6%)

Query  1    MAKYPFETIEPKWQAYWEKNKTFKVTEDMKFEPSKRTYVLDMFPYPSAQGLHVGHPEGYT  60
            M+ Y   +IEPKWQA+W  N TFK   D    +  + Y LDMFPYPS+ GLHVGHPEGYT
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTD---ASKPKFYALDMFPYPSGAGLHVGHPEGYT  57

Query  61   ATDIYCRYLRMNGYNVLHPMGYDAFGLPAENYAIKTGTHPAATTNANIEHFTQQIKALGF  120
            ATDI  R+ R +G NVLHPMG DAFGLPAE+YA+ TG +PA  T  NI +F +QI+ALGF
Sbjct  58   ATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGF  117

Query  121  SYDWDRCVSTCTPDYYHWTQWIFLQLYKKGLAYEAETPINWCPSCLTGLANEEV-KEGRC  179
            SYDWDR V+T  P+YY WTQWIF +LY KGLAYEAE P+NW     T++ANEEV  +G  
Sbjct  118  SYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTS  177

Query  180  DRCGAAVSRKTIRQWILRITAYADRLLEDLDSLDWPESVKLMQKNWIGKSEGAEVSFKIA  239
            +R G +V RK +RQW+L+ITAYA+RLLEDL+ +DWPES+K MQ+NWIGKS GA+V+FK+ 
Sbjct  178  ERGGYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKV-  236

Query  240  APDGSATEDELLVYTTRADTLHGATYMVIAPEHTLVSRLTTaaqkaavdayvdaaakkSD  299
                  T+ ++ V+TTR+DTL GATY V+APEH+LV  +TT+ Q  AV  Y   A+ KSD
Sbjct  237  ----KDTDKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSD  292

Query  300  LERTDLAKDKTGVFTGSYAVNPVNGDKIPIWISDYILISYGTGAIMAVPAHDERDWAFAR  359
            L RTDLAK+KTGV TGSYA+NPVNG  +P+WI+DY+L SYGTGAIMAVPAHDERDW FA+
Sbjct  293  LARTDLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAK  352

Query  360  KFDLPIRKVVASKEEIASLADGNEAEGACRLTRaaadaaayealvkaHPDVFNTAAECTA  419
            +F+L I         I+ L +GN  E+A                               +
Sbjct  353  QFNLDI---------IPVLEGGNVEEAAF------------------------------T  373

Query  420  ADGYTINSGTFTGMPTARTIPAMIEWLTRDGIGKKAVNYKLRDWVFSRQRYWGEPMPLVH  479
             DG  INS+ + G+  A +I+ M+EWL  +G+G+  V Y+LRDW+FSRQRYWGEP+P++H
Sbjct  374  EDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIH  433

Query  480  CQKCGCVpldekdlplllpdVKTYQPTGTGESPLAGIDEWVNCTCPKCGGKAKRETNTMP  539
             +     ++ E +LPL+LP  K  +P+GTGESPLA + +W++ T    G K++RETNTMP
Sbjct  434  WEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED-GVKGRRETNTMP  492

Query  540  QWAGSCWYYLRYLDPHNTKEFASQDAVKYWMPVDLYVGGAEHAVLHLLYARFWHKVLYDL  599
            QWAGS WYYLRY+DPHNT  +A ++ +K W+PVD+YVGGAEHAVLHLLYARFWHKVLYDL
Sbjct  493  QWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDL  552

Query  600  GLVQTKEPFQRLVNQGMITSFAFQRKNKTLVATDAVTETESGVFVETATGEKLERVIAKM  659
            G+V TKEPFQ+L NQGMI + +++    +LVATD V E   G F +  TGE LE+  AKM
Sbjct  553  GVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKV-EKRDGSFFHVETGEELEQAPAKM  611

Query  660  SKSLKNVVNPDDVIKEYGADSVRMYEMFMGPLEVSKPWNTQGLIGINRFLEKI-WAVSEK  718
            SKSLKNVVNPDDV+ +YGAD++R+YEMFMGPL+ S +W+ +GL G  +FL+++ + ++ K
Sbjct  612  SKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTK  671

Query  719  SIVDIPVDGELDKEFTALRKTFHKTVKKVTEDTAALNFNTAISQMMIFINEAAKIESLPR  778
             I         + +  AL K ++ TVK VTE+   ++FNTAI+Q+M+F+N A K + L  
Sbjct  672  EIT--------EENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFS  723

Query  779  AIWSDFVKLLSVYAPHIGEELWEKL-GHDTTIAYEPWPVYNEAFCTDDTCTIVVQVNGKK  837
                +FV+L++ +APH+GEELW+ L + + +I+Y PWP Y+E+   ++   IVVQ++GK 
Sbjct  724  DYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKV  783

Query  838  RDEFSAAIDTDKAVLEKTAMETD  860
            +  +  A D  +  L+  A+  +
Sbjct  784  KAKLVVAKDLSREELQEVALANE  806

458) leuS in NC_021280


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  734 bits (2775),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 451/825 (55%), Positives = 599/825 (73%), Gaps = 46/825 (5%)

Query  3    FSHKAIEQKWQKYWAEHNTFATNTNFSK-KAYILDMFPYPSGAGLHVGHPKGYTATDVIS  61
            + H AIE KWQ +WA+++TF T T+ SK K Y LDMFPYPSGAGLHVGHP GYTATD++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  62   RMRRLQQYNVLHPIGWDAFGLPAEQYALQTGNDPADFTLKNIDNFRNQLKALGFSYDYEK  121
            R +R Q  NVLHP+GWDAFGLPAEQYA++TGNDPA+FT  NI NF+ Q++ALGFSYD ++
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  122  EVNTSAPWYFKTTQWIFEKLYQQGLAEVREVDVNWCPELGTVLANEEVFVVDGKMVSERG  181
            EVNT+ P Y+K TQWIF KLY++GLA   EV VNW  ELGT +ANEEV + DG   SERG
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEV-LPDG--TSERG  180

Query  182  SFPVYKKPMKQWVLKITAYAEQLISGLDELDWPQSVKDLQKNWIGKSVGAEIKFAVADMP  241
            ++PV +KPM+QW+LKITAYAE+L+ +L+E+DWP+S+KD+Q+NWIGKS GA++ F V D  
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  242  NEVTVFSTRADTIFGVEYLVLAPEHPLVLSLVTPENLASTKEYLELVKTKTELDRQDTSK  301
            ++ TVF+TR+DT+FG  Y VLAPEH+LV ++ T+++  +  +Y      K++L R D +K
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  302  EKTGIFLGRYAINPVNNKKIPIWTADYVLSHYGAGAVMAVPGHDERDYLFAKKYNLPISY  361
            EKTG+  G YAINPVN K +P+W ADYVL+ YG+GA+MAVP+HDERD  FAK++NL I  
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  362  VIKNSN-HNGPFLKDGEHINSDFLDGLNTKQASEKALSVLGEKKIAQPKITYKLKDWLFS  420
            V+  +N ++++F  DG HINSDFLDGL+   A  K +  L    +++ ++TY+L+DWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  421  RQRYWGEPFPIIHWEDGSISLVPESELPLTLPKMDNITPSTTGESPLANATDWLTVTDAT  480
            RQRYWGEP+PIIHWEDG+ + VPESELPL LP   +I PS TGESPLAN TDWL VT   
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  481  GKKGRRETNTMPQWAGSCWYYLAYPLMIGQEEMLDLASPEGQAALKEWLPVDLYVGGQEH  540
            G KGRRETNTMPQWAGS WYYL Y   I+ ++   LA   ++  LK+WLPVD+YVGG EH
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRY---IDPHNTEKLA---DEELLKQWLPVDIYVGGAEH  534

Query  541  AVLHLLYARFWHKVLFDQNLVPTSEPFIKLVNQGMILGPD--------------------  580
            AVLHLLYARFWHKVL+D  +VPT EPF KL NQGMILG                      
Sbjct  535  AVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGS  594

Query  581  -------------GSKMSKSKGNVINPDDIIKSHGADSLRLYEMFMGPIEASLPWNETGL  627
                          +KMSKS  NV+NPDD++   GAD+LR+YEMFMGP++AS++W+E GL
Sbjct  595  FFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGL  654

Query  628  DSMRKWLDRIYRLVKNNNFTTVNDKTLDFAYHQMVKKTTEMLENLSFNTAISQLMVFINA  687
            ++ RK LDR+YRL+  +++T  N  +LD  Y++ VK  TE ++++ FNTAI+QLMVF+NA
Sbjct  655  EGSRKFLDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNA  714

Query  688  CYKTDQPIYQPYFEGFTKILSCFAPHLAEEIWSNF-GYQTSINNGQWPIYETKYLQKTTL  746
              K D+ ++  Y  GF ++++ FAPHL+EE+W  + +   SI+   WP Y+   L    +
Sbjct  715  ANKEDK-LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDV  773

Query  747  IVAVQVNGKLRAKLDVPVDTPeaellllakeheNIQGILATHDIL  791
             + VQ++GK++AKL V+ D +  EL  +A  +E++Q+ +A  DI+
Sbjct  774  EIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDII  818

459) leuS in NC_017717


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  733 bits (2773),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 419/816 (52%), Positives = 599/816 (74%), Gaps = 15/816 (1%)

Query  1    MSKYEFIKIEKKWQEFWDNNKTYKVKEDPNIPKEKRLYILDMFPYPSANGLHVGHPEGYT  60
            M+ Y+   IE KWQ FW +N T+K   D++ PK   +Y LDMFPYPS+ GLHVGHPEGYT
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPK---FYALDMFPYPSGAGLHVGHPEGYT  57

Query  61   ATDIFGRYKLLNGFHVLHPIGFDSFGLPAENYAIQTGTHPQKSTEENINKFKKQIKALGF  120
            ATDI++R+K  +G +VLHP+G D+FGLPAE+YA++TG +P   T ENI +FK+QI+ALGF
Sbjct  58   ATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGF  117

Query  121  AYDWDREIRTHDENYYKWTQWIFLELYKKGLAYAKEMPVWYCPELGTVLANEEIIQTPDG  180
            +YDWDRE+ T D NYYKWTQWIF  LY KGLAY  E+PV    ELGT +ANEE++  PDG
Sbjct  118  SYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVL--PDG  175

Query  181  PKSERGFHNVEKKYLRQWVLKITKYAERLLNDLEELEWPESVKEMQRNWIGKSTGVEIDF  240
              SERG   V +K +RQW+LKIT YAERLL+DLEE++WPES+K+MQRNWIGKSTG ++ F
Sbjct  176  T-SERGGYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTF  234

Query  241  EIEGHNDKIKVFTTRPDTIFGITYLVIAPESKLIEKITKNNFKRNVLKYVKHEELKSDLK  300
             + + +  + VFTTRPDT+FG TY V+APE  L++ IT ++    V  Y ++  LKSDL 
Sbjct  235  KVKDTDKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLA  294

Query  301  RTSLEKDKSGVFTGSYAFHPITNEKIPIWVGSYVLGTYGSGAVMGVPAHDERDFQFAKKY  360
            RT L K+K+GV TGSYA++P+    +P+W++ YVL++YG+GA+M+VPAHDERD +FAK++
Sbjct  295  RTDLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQF  354

Query  361  KLKILPVISKSGKNEILEKAFIDDGISINSPNEF-NNLKNSEVKDKVIEWLIKNKKGKEK  419
            +L I+PV+  +   ++ E AF +DG+ INS  +F + L ++    K++EWL  +  G+E+
Sbjct  355  NLDIIPVLEGG---NVEEAAFTEDGLHINS--DFLDGLDKASAIAKMVEWLEAEGVGNEN  409

Query  420  VTYKLRDWIFSRQRYWGEPIPILFDKLGNAIPLEKNDLPLKLPETANYKPSRTGESPLSR  479
            VTY+LRDW+FSRQRYWGEPIPI+    G + ++  ++LPL LP T + +PS TGESPL+ 
Sbjct  410  VTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLAN  469

Query  480  IKDWVNL-KDTGFT--RETNTMPQWAGSCWYYLRYLDPKNPKEFASKKKIEYWMPVDLYI  536
            + DW+++ ++ G    RETNTMPQWAGS WYYLRY+DP N   +A    +  W+PVD+Y+
Sbjct  470  VTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYV  529

Query  537  GGAEHTVLHLLYSRFWHKVLYDLGYVNTKEPFKKLINQGIITAFSYQKENGILIPNDQVI  596
            GGAEH+VLHLLY+RFWHKVLYDLG V TKEPF+KL+NQG+I + SY+   G L++ D+V 
Sbjct  530  GGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVE  589

Query  597  EkdnkffdkrdnkEVTQVIAKMSKSLKNVINPDDIIKEFGADSIRIYEMFMGPLTDSKPW  656
             +D  FF+     E+ Q  AKMSKSLKNV+NPDD++ ++GAD++R+YEMFMGPL  S +W
Sbjct  590  KRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAW  649

Query  657  NTKGIIGVFRFLNKIWNLRKKELSKDNPPKEIISQLHKAIKKVTEDTEKLNFNTAISAMM  716
            +  G+ G  +FL+++  L       ++ +  +    + ++K VTE+ ++++FNTAI+ +M
Sbjct  650  SEEGLEGSRKFLDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLM  709

Query  717  IFVNELLKYEKNYLNIFKPFIIILSPYAPHLAEELWEYIGETPSLFKNSKWPEFDENLII  776
            +FVN   K +K + +  K F+ +++P+APHL+EELW+ +  +   +    WP +DE+ ++
Sbjct  710  VFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLV  769

Query  777  KDAKEIVLQINGKIKDKILLSKETDEEELKEIAMGN  812
             +  EIV+QI+GK+K K++++K+   EEL+E+A++N
Sbjct  770  ENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALAN  805

460) BgCN_0255 in NC_018747


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  732 bits (2770),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 419/816 (52%), Positives = 599/816 (74%), Gaps = 15/816 (1%)

Query  1    MSKYEFIKIEKKWQEFWDNNKTYKVKEDPNIPKEKRLYILDMFPYPSANGLHVGHPEGYT  60
            M+ Y+   IE KWQ FW +N T+K   D++ PK   +Y LDMFPYPS+ GLHVGHPEGYT
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPK---FYALDMFPYPSGAGLHVGHPEGYT  57

Query  61   ATDIFGRYKLLNGFHVLHPIGFDSFGLPAENYAIQTGTHPQKSTEENINKFKKQIKALGF  120
            ATDI++R+K  +G +VLHP+G D+FGLPAE+YA++TG +P   T ENI +FK+QI+ALGF
Sbjct  58   ATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGF  117

Query  121  AYDWDREIRTHDENYYKWTQWIFLELYKKGLAYAKEMPVWYCPELGTVLANEEIIQTPDG  180
            +YDWDRE+ T D NYYKWTQWIF  LY KGLAY  E+PV    ELGT +ANEE++  PDG
Sbjct  118  SYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVL--PDG  175

Query  181  PKSERGFHNVEKKYLRQWVLKITKYAERLLNDLEELEWPESVKEMQRNWIGKSTGVEIDF  240
              SERG   V +K +RQW+LKIT YAERLL+DLEE++WPES+K+MQRNWIGKSTG ++ F
Sbjct  176  T-SERGGYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTF  234

Query  241  EIEGHNDKIKVFTTRPDTIFGITYLVIAPESKLIEKITKNNFKRNVLKYVKHEELKSDLK  300
             + + +  + VFTTRPDT+FG TY V+APE  L++ IT ++    V  Y ++  LKSDL 
Sbjct  235  KVKDTDKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLA  294

Query  301  RTSLEKDKSGVFTGSYAFHPITNEKIPIWVGSYVLGTYGSGAVMGVPAHDERDFQFAKKY  360
            RT L K+K+GV TGSYA++P+    +P+W++ YVL++YG+GA+M+VPAHDERD +FAK++
Sbjct  295  RTDLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQF  354

Query  361  KLKILPVISKSGKNEILEKAFIDDGISINSPNEF-NNLKNSEVKDKVIEWLIKNKKGKEK  419
            +L I+PV+  +   ++ E AF +DG+ INS  +F + L ++    K++EWL  +  G+E+
Sbjct  355  NLDIIPVLEGG---NVEEAAFTEDGLHINS--DFLDGLDKASAIAKMVEWLEAEGVGNEN  409

Query  420  VTYKLRDWIFSRQRYWGEPIPILFDKLGNAIPLEKNDLPLKLPETANYKPSRTGESPLSR  479
            VTY+LRDW+FSRQRYWGEPIPI+    G + ++  ++LPL LP T + +PS TGESPL+ 
Sbjct  410  VTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLAN  469

Query  480  IKDWVNL-KDTGFT--RETNTMPQWAGSCWYYLRYLDPKNPKEFASKKKIEYWMPVDLYI  536
            + DW+++ ++ G    RETNTMPQWAGS WYYLRY+DP N   +A    +  W+PVD+Y+
Sbjct  470  VTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYV  529

Query  537  GGAEHTVLHLLYSRFWHKVLYDLGYVNTKEPFKKLINQGIITAFSYQKENGILIPNDQVI  596
            GGAEH+VLHLLY+RFWHKVLYDLG V TKEPF+KL+NQG+I + SY+   G L++ D+V 
Sbjct  530  GGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVE  589

Query  597  EkdnkffdkrdnkEVTQVIAKMSKSLKNVINPDDIIKEFGADSIRIYEMFMGPLIDSKPW  656
             +D  FF+     E+ Q  AKMSKSLKNV+NPDD++ ++GAD++R+YEMFMGPL  S +W
Sbjct  590  KRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAW  649

Query  657  NTKGIIGVFRFLNKIWNLREKELSKDNPPKEIISQLHKAIKKVTEDTEKLNFNTAISAMM  716
            +  G+ G  +FL+++  L       ++ +  +    + ++K VTE+ ++++FNTAI+ +M
Sbjct  650  SEEGLEGSRKFLDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLM  709

Query  717  IFVNELLKYEKNYLNIFKPFIIILSPYAPHLAEELWEYIGETPSLFKNSKWPEFDENLII  776
            +FVN   K +K + +  K F+ +++P+APHL+EELW+ +  +   +    WP +DE+ ++
Sbjct  710  VFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLV  769

Query  777  KDAKEIVLQINGKIKDKILLSKETDEEELKEIAMGN  812
             +  EIV+QI+GK+K K++++K+   EEL+E+A++N
Sbjct  770  ENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALAN  805

461) leuS in NC_007514


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  730 bits (2761),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 450/844 (54%), Positives = 612/844 (73%), Gaps = 55/844 (6%)

Query  3    YDFTSIEKKWQTRWQAEATFATGTDHSKPKYYVLDMFPYPSGSGLHVGHLEGYTASDIIA  62
            YD T+IE KWQ+ W  + TF TGTD SKPK+Y LDMFPYPSG+GLHVGH EGYTA+DI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRSSGYNVLHPMGWDAFGLPAEQFAIKTGTHPRITTEANVKNFKGTLQAMGFSYDWER  122
            R+KR+ G NVLHPMGWDAFGLPAEQ+A+ TG +P   T  N+ NFK  ++A+GFSYDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EINTTDSGYFKWTQWIFLQLYDRGLAYMSEVDVNWCEELKTVLANEEV---DEKLADGYT  179
            E+NTTD+ Y+KWTQWIF +LY++GLAY +EV VNW EEL T +ANEEV   +    +GY 
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  180  VVRRPLRQWVLKITAYaerlladleeldWPENVKQMQRNWIGRSEGVEIDFELRCHRTTL  239
            VVR+P+RQW+LKITAYAERLL DLEE+DWPE++K+MQRNWIG+S G ++ F ++     +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  240  KAYTTRPDTLFGATYLVIAPEHPMAEKLATAPQLLVVKEYITKAKLKSDLERTGLQKEKS  299
              +TTRPDTLFGATY V+APEH++ + ++T+ Q   V +Y  +A LKSDL RT+L KEK+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  300  GVFTGSYAINPATGQPLPIWISDFVLISYGTGAIMSVPAHDSRDWAFAKQYNLPIIEVIK  359
            GV TGSYAINP  G+ +P+WI+D+VL SYGTGAIM+VPAHD RDW FAKQ+NL II V+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  360  SPHDVQEAVFEEKNSTCVNSANDEISLNGLDFATAFERMATWLESKKVGKRKVNYKLRDW  419
            + + V+EA F E ++  +NS      L+GLD A+A+ +M  WLE+  VG+ +V Y+LRDW
Sbjct  364  GGN-VEEAAFTE-DGLHINSD----FLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDW  417

Query  420  IFSRQRYWGEPIPIKHYEDGTIR--PETNLPLELPAVEAYHPTSTGESPLANITEWL-IG  476
            +FSRQRYWGEPIPI H EDGT    PE++LPL LP     +P++TGESPLAN+T+WL + 
Sbjct  418  LFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT  477

Query  477  NDEHGAFRRETNTMPQWAGSCWYYLRFIDPHNHAQVVDGNNERYWMNVDLYIGGAEHAVL  536
             ++    RRETNTMPQWAGS WYYLR+IDPHN  ++ D +  + W+ VD+Y+GGAEHAVL
Sbjct  478  REDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVL  537

Query  537  HLLYSRFWHKVLYDLGVVSTKEPFQKLFNQGMILG-------------------------  571
            HLLY+RFWHKVLYDLGVV+TKEPFQKLFNQGMILG                         
Sbjct  538  HLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFH  597

Query  572  --------EDNEKMSKSRGNVIPADHVLQRYGADAVRLYEMFLGPLEQVKPWNTNGIEGI  623
                    +   KMSKS  NV+ +D+V+++YGAD++R+YEMF+GPL+   +W+ +G+EG 
Sbjct  598  VETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGS  657

Query  624  SRFLGKVWRFVYPEHSEAATQPSNEPLPDELLRRMHKTIKKVGDDTSSLKFNTAIAEMMV  683
             +FL++V R++       +T+   E  ++ L +  + T+K V ++   +KFNTAIA++MV
Sbjct  658  RKFLDRVYRLI-------TTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMV  710

Query  684  FVNELTKTGCNNREAIETLLKLLAPYAPHMTEELWEAL-GHTNSISHEPFPTFNPA-LVE  741
            FVN   K +    +    +++L+AP+APH+ EELW+AL +  +SIS  P P+++ + LVE
Sbjct  711  FVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVE  770

Query  742  ENMAIIAVQVNGKLRGTFTVPAKSPKEMLLEEARKVESVAKFLEGKTIVKEIVVPDKLVN  801
            +++ I+ VQ++GK+++ + V+   ++E L E A   E V   + GK I+K I VP+KLVN
Sbjct  771  NDVEIV-VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVN  829

Query  802  FAVK  805
            + +K
Sbjct  830  IVIK  833

462) leuS in NC_011060


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  730 bits (2761),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 442/832 (54%), Positives = 603/832 (73%), Gaps = 55/832 (6%)

Query  3    YEFSKTEAKWQAWWKEQNTFKTGDDADKPKYYVLDMFPYPSGTGLHVGHLEGYTASDITA  62
            Y+ +  E+KWQA W +++TFKTG DA KPK+Y LDMFPYPSG+GLHVGH EGYTA+DI +
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRSCGYNVLHPMGWDAFGLPAEQFAIKTGTHPKTTTEENIRNFKGTLQAMGFSYDWSR  122
            R+KR+ G NVLHPMGWDAFGLPAEQ+A+ TG +P   T ENI NFK  ++A+GFSYDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EINTTDPHYFKWTQWIFLKLYERGLAYMSEVDVNWCEELKTVLANEEV---DEKIADGYT  179
            E+NTTDP+Y+KWTQWIF KLYE+GLAY +EV VNW EEL T +ANEEV   +    +GY 
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  180  VVRRPLRQWVLKITAYADRLLADLDELNWPENVKQMQRNWIGRSEGVEIDFELRCHNKKL  239
            VVR+P+RQW+LKITAYA+RLL DL+E++WPE++K+MQRNWIG+S G ++ F ++  +K +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  240  RVYTTRPDTLFGATYLVISPEHPLAEKLATAQQLVEVKNYISKAKLKTELERTGLQKEKT  299
             V+TTRPDTLFGATY V++PEH+L + ++T++Q   V +Y  +A LK++L RT+L KEKT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  300  GVFTGSYAINPATGEPLPVWISDFVLISYGTGAIMSVPAHDSRDWEFAKQYNLPIIEVIQ  359
            GV TGSYAINP  G  +PVWI+D+VL SYGTGAIM+VPAHD RDWEFAKQ+NL II V++
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  360  SPHDVQERVFEEKESICVNSANNEITLNGLPFCEAFERMASWLETKKAGERKVNYKLRDW  419
            + + V+E  F E +++ +NS      L+GL    A+ +M  WLE+   G+ +V Y+LRDW
Sbjct  364  GGN-VEEAAFTE-DGLHINSD----FLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDW  417

Query  420  IFSRQRYWGEPIPIKHYHDGTLRL--ETALPLVLPEVEAYHPSSTGESPLANIPHWLYGS  477
            +FSRQRYWGEPIPI H +DGT     E+ LPLVLP     +PS+TGESPLAN+ +WL  +
Sbjct  418  LFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT  477

Query  478  DEHG-SFRRETNTMPQWAGSCWYYLRFIDPENQEKLVDPEKERYWMNVDLYIGGAEHAVL  536
             E+G   RRETNTMPQWAGS WYYLR+IDP+N EKL D E  + W+ VD+Y+GGAEHAVL
Sbjct  478  REDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVL  537

Query  537  HLLYARFWHKVLFDLGVVSSREPFKKLFNQGMILG-------------------------  571
            HLLYARFWHKVL+DLGVV+++EPF+KLFNQGMILG                         
Sbjct  538  HLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFH  597

Query  572  --------EDNEKMSKSRGNVIPADHVLERYGADAVRLYEMFLGPLEQVKPWNTNGIEGI  623
                    +   KMSKS  NV+ +D+V+E+YGAD++R+YEMF+GPL+   +W+ +G+EG 
Sbjct  598  VETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGS  657

Query  624  SRFLSKVWRLVYGEHEESATLLSEEAMPEELLRRMHKSIKKVGEDTEQLKFNTAISEMMV  683
             +FL +V RL+      ++  ++EE  +  L +  + ++K V E+ +Q+KFNTAI+++MV
Sbjct  658  RKFLDRVYRLI------TTKEITEEN-SGALDKVYNETVKAVTEQVDQMKFNTAIAQLMV  710

Query  684  FVNELQKSGCKNRSAIETLLVLLSPYAPHITEELWESI-GHNYSISQAPFPSFD-PKLVE  741
            FVN  +K +         ++ L++P+APH+ EELW+++ +   SIS  P PS+D +KLVE
Sbjct  711  FVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVE  770

Query  742  ESILTIAVQINGKLRGTFLAPAKSPKELLLQEAKKTESVFKFLDGQTILREI  793
            + +  I VQI+GK+++ ++ +   ++E L + A   E V   + G+ I++ I
Sbjct  771  NDV-EIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVI  821

463) leuS in NC_015431


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  729 bits (2756),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 428/840 (51%), Positives = 607/840 (73%), Gaps = 50/840 (5%)

Query  3    FSHKAIEKKWQKYWKENNIYKTTNNSEK-KAYILDMFPYPSGAGLHVGHIKGYTATDVYS  61
            + H AIE KWQ +W +N+ +KT  ++ K K Y LDMFPYPSGAGLHVGH  GYTATD+ S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  62   RFKRMQGYDVLHPIGWDAFGLPAEQYALKTGNDPREFTLQNIENFKIQLNKMGFSYDYDK  121
            RFKR QG +VLHP+GWDAFGLPAEQYA+ TGNDP EFT +NI NFK Q+N +GFSYD D+
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  122  EINTADPNYYKTTQWIFKQLYKKGLAENRDIDVNWCQELGTVLANDEIIEKDGLMVSERG  181
            E+NT+DPNYYK TQWIF +LY KGLA + ++ VNW +ELGT +AN+E++  +    SERG
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDG---TSERG  180

Query  182  EYPVVKKKMRQWVLKITDYADKLLDGLDNLDWPNSVKELQRNWIGKSEGCEINFKSNDI-  240
             YPVV+K MRQW+LKIT YA++LL++L+++DWP+S+K++QRNWIGKS G ++ FK +D  
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  241  -NIPVFTTRADTIFGATYIVLAPENELVLKLTTPEKLDEVKKYIELTANKSEIERKDESR  299
             ++ VFTTR+DT+FGATY VLAPE+ LV  +TT+++ + V  Y   ++ KS++ R D ++
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  300  TKTGVFIGSYATNPLTKEQIQIWISDYVLNDYGSGAIMAVPAHDKRDWDFATKFDLPIRF  359
             KTGV  GSYA NP+   ++ +WI+DYVL  YG+GAIMAVPAHD RDW+FA +F+L I  
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  360  VIQTKD-QSKAFVGEGIHINSEFLNDLDRVQALQVIHDYVEKNNLGKRKINYKLRDWLFS  418
            V++  + +  AF  +G+HINS+FL++LD+  A+  + + +E + +G+ ++ Y+LRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  419  RQRFYGEPFPVLYDKDNNIVLIEDNNLPITLPTTDYIKPTNNGESPLANVKNWVNVKIGD  478
            RQR+ GEP+P++   D     + +++LP+ LP T  I+P+  GESPLANV +W++V   D
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  479  K-EYKRETNTMPQSAGSSWYFIAYILADSKNNLIDLTSDEAKKRLEKWLPVDLYIGGQEH  537
                +RETNTMPQ AGSSWY++ YI +++ ++L D         L +WLPVD+Y+GG EH
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLAD------EELLKQWLPVDIYVGGAEH  534

Query  538  AVGHLLYSRFWTHFLYDLGLLPTNEPFKRLFNQGMILGPDNR------------------  579
            AV HLLY+RFW   LYDLG++PT+EPF++LFNQGMILG   R                  
Sbjct  535  AVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGS  594

Query  580  ---------------KMSKSWGNVINPDDVIDTHGSDALRLYEMFMGPLDASLPWSFDGL  624
                           KMSKS  NV+NPDDV++  G+D+LR+YEMFMGPLDAS++WS +GL
Sbjct  595  FFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGL  654

Query  625  DASLKWLNRCYRMINKIEFSNTNNHKLDYVYNDVVKKVTQMIQELKFNTAISQLMVLVNA  684
            ++S K L+R YR+I   E+++ N+  LD VYN+ VK VT+ ++++KFNTAI+QLMV+VNA
Sbjct  655  EGSRKFLDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNA  714

Query  685  IYKEELNTVYKPYIEGFVKMLSLFAPHLSEELWEKL-GNNSSVTLQTWPEFDETKIIKNT  743
              KE+   ++  Y  GFV++++ FAPHL+EELW+ L ++  S++   WP +DE+K++ N 
Sbjct  715  ANKED--KLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVEND  772

Query  744  VVIALQVNGKLRSTIEVEKGTDKETLINLAEKNENIIKFIKDHKILKRIAVIDRIVNIVI  803
            V I +Q++GK+++ + V K+  +E L ++A  NE++   I +  I+K IAV +++VNIVI
Sbjct  773  VEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

464) leuS in NC_015578


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  728 bits (2753),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 458/856 (54%), Positives = 601/856 (71%), Gaps = 61/856 (7%)

Query  9    YPFETIEPKWQKYWADHQTFKAVEDPSFPKDKRRYVLDMFPYPSAQGLHVGHPEGYTATD  68
            Y   +IEPKWQ +WAD++TFK+  D+S PK    Y LDMFPYPS+ GLHVGHPEGYTATD
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPK---FYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  69   IYCRYLRMNGYNVLHPMGFDAFGLPAENYAIKTGTHPSVTTAANINHFRTQIKSLGFSYD  128
            I  R+ R +G NVLHPMG DAFGLPAE+YA+ TG +P+  TA NI +F+ QI++LGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  129  WDREVDTSNEKYYRWTQWIFLKLFEKGLAYEAESPINWCPSCKTGLANEEV-KDGCCDRC  187
            WDREV+T++ +YY+WTQWIF KL+EKGLAYEAE P+NW     T++ANEEV  DG  +R 
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  188  GTKVSRKRIRQWILKITAYAERLLDDLDGLDWPEPVKLMQRNWIGRSEGANVIFKIDGHS  247
            G  V RK +RQW+LKITAYAERLL+DL+ +DWPE++K MQRNWIG+S GANV FK+ +  
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  248  EALEIYTTRPDTLFGATYMVLSPEHSLVEKITTPDQKAAVGAYLDAAAKKSDLERTDLAK  307
              + ++TTRPDTLFGATY VL+PEH+LV+ ITT+DQ  AV+ Y   A+ KSDL RTDLAK
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  308  EKTGVFSGAYAVNPVNGAKIPIWIADYVLISYGTGAIMAVPAHDERDWDFAKAFNLPIIQ  367
            EKTGV +G+YA+NPVNG  +P+WIADYVL SYGTGAIMAVPAHDERDW+FAK FNL II 
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  368  VVSPVPPGGESAGFSDGNTEGISTCTVADGWSVNSGDFTGLPTTEAKEKVTAWVEAQGFG  427
            V+       E A+F++            DG  +NS+ + GL  + A  K+  W+EA+G G
Sbjct  361  VLE--GGNVEEAAFTE------------DGLHINSDFLDGLDKASAIAKMVEWLEAEGVG  406

Query  428  KKTVNYKLRDWIFSRQRYWGEPIPLVHCEHCGIVplpetelplrlpDVQSYTPTGTGESP  487
            +  V Y+LRDW+FSRQRYWGEPIP++H E+    ++PE+ELPL LP  +   P+GTGESP
Sbjct  407  NENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESP  466

Query  488  LAGITDWVNTTCPVCGGPAKRETNTMPQWAGSCWYYLRYLDPDNDTAFAAKDKIDYWAPV  547
            LA +TDW++ T    G  ++RETNTMPQWAGS WYYLRY+DP+N   +A  + +  W PV
Sbjct  467  LANVTDWLEVTRE-DGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPV  525

Query  548  DLYVGGVEHAVLHLLYSRFWHKVLYDLGLVNTKEPFQRLVNQGMILG-------------  594
            D+YVGG EHAVLHLLY+RFWHKVLYDLG+V TKEPFQ+L NQGMILG             
Sbjct  526  DIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVAT  585

Query  595  --------------------EDNLKMSKSRGNVINPDDIVKSFGADSMRVYEMFMGPLEV  634
                                +   KMSKS  NV+NPDD+V  +GAD++RVYEMFMGPL+ 
Sbjct  586  DKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  635  TKPWLTAGLVGVSRFLERLWAIAEKPLTEKSPTEALGAEQAEELVRLQHKTIKKVSRDTG  694
            + +W   GL G  +FL+R+  +          T  +  E++  L ++ + T+K V+ + +
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLI--------TTKEITEENSGALDKVYNETVKAVTEQVD  697

Query  695  SLDFNTAISQMMVYSNELAKLAELPRSLWEPLVLMVSAYAPHLGEELWEKLGHSG-SVSK  753
             + FNTAI+Q+MV+ N   K   L       +V +++++APHLGEELW+ L  SG S+S 
Sbjct  698  QMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISY  757

Query  754  AAWPVWEEKLTADNEVTVVAQVNGKIRDKFTAAAGTSKEELEKIALALPGVLKWLDGQTV  813
             +WP  +E    +N+V +V Q++GK++ K+  A + S+EEL+ +ALA   V   + G+ +
Sbjct  758  VPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDI  817

Query  814  VKVIAVQDKLVNIVVK  829
            +KVIAV +KLVNIV+K
Sbjct  818  IKVIAVPNKLVNIVIK  833

465) leuS in NC_017403


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  728 bits (2753),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 419/823 (51%), Positives = 607/823 (74%), Gaps = 15/823 (1%)

Query  1    MSKYEFIKIEKKWQEFWDNNKTYKVEEDPSIPKEKRLYILDMFPYPSANGLHVGHPEGYT  60
            M+ Y+   IE KWQ FW +N T+K   D+S PK   +Y LDMFPYPS+ GLHVGHPEGYT
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPK---FYALDMFPYPSGAGLHVGHPEGYT  57

Query  61   ATDIFGRYKLLNGFHVLHPIGFDSFGLPAENYAIQTGTHPQKSTEENINKFKKQIKALGF  120
            ATDI++R+K  +G +VLHP+G D+FGLPAE+YA++TG +P   T ENI +FK+QI+ALGF
Sbjct  58   ATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGF  117

Query  121  AYDWDREIRTHEENYYKWTQWIFLQLYKKGLAYVKEMPVWYCPELGTVLANEEIIQTSDG  180
            +YDWDRE+ T + NYYKWTQWIF +LY KGLAY  E+PV    ELGT +ANEE++  +  
Sbjct  118  SYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDG--  175

Query  181  PKSERGSYSVEKKYLRQWVLKITKYAerllddleeleWPESVKEMQRNWIGKSTGVEIEF  240
              SERG+Y+V +K +RQW+LKIT YAERLL+DLEE++WPES+K+MQRNWIGKSTG ++ F
Sbjct  176  -TSERGGYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTF  234

Query  241  EIEGHSDKIKVFTTRPDTIFGITYLVIAPENKLIEKITKNNFKQNVLKYVKREELKSDLN  300
             + +    + VFTTRPDT+FG TY V+APE+ L++ IT ++  + V  Y ++  LKSDL 
Sbjct  235  KVKDTDKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLA  294

Query  301  RTSLEKDKSGVFTGSYAFHPITNEKIPIWVGSYVLGTYGTGAVMGVPAHDERDFQFAKKY  360
            RT L K+K+GV TGSYA++P+    +P+W++ YVL++YGTGA+M+VPAHDERD +FAK++
Sbjct  295  RTDLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQF  354

Query  361  QLKILPVISKSGKNEILEKAFIDDGISINSPNEF-NNLKNSEVKDKVIKWLTKNKKGKEK  419
            +L I+PV+  +   ++ E AF +DG+ INS  +F + L ++    K++ WL  +  G+E+
Sbjct  355  NLDIIPVLEGG---NVEEAAFTEDGLHINS--DFLDGLDKASAIAKMVEWLEAEGVGNEN  409

Query  420  VTYKLRDWIFSRQRYWGEPIPILFDKLGNAIPLEENDLPLKLPEIANYKPSGTGESPLSR  479
            VTY+LRDW+FSRQRYWGEPIPI+    G + ++ E++LPL LP   + +PSGTGESPL+ 
Sbjct  410  VTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLAN  469

Query  480  IKDWVNV-KDMGFT--RETNTMPQWAGSCWYYLRYLDPKNSKEFANKKKIEYWMPVDLYI  536
            + DW++V ++ G    RETNTMPQWAGS WYYLRY+DP N+  +A+   +  W+PVD+Y+
Sbjct  470  VTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYV  529

Query  537  GGAEHTVLHLLYSRFWHKVLYDLGYVNTKEPFKKLINQGIITSFSYQKENGVLIPNDQVI  596
            GGAEH+VLHLLY+RFWHKVLYDLG V TKEPF+KL+NQG+I + SY+   G L++ D+V 
Sbjct  530  GGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVE  589

Query  597  EkdnkffdkkdnkEVTQVIAKMSKSLKNVINPDDIIKEFGADSMRIYEMFMGPLTDSKPW  656
             +D  FF+     E+ Q  AKMSKSLKNV+NPDD++ ++GAD++R+YEMFMGPL  S +W
Sbjct  590  KRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAW  649

Query  657  NTKGIIGVFRFLNKIWNLREKELSKDNPPKEIISELHKVIKKVTEDTEKLNFNTAISAMM  716
            +  G+ G  +FL+++  L       ++ +  +    +  +K VTE+ ++++FNTAI+ +M
Sbjct  650  SEEGLEGSRKFLDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLM  709

Query  717  IFINELLKYEKNYLNIFKPFIIILSPYAPHLAEELWEYIGELPSLFKNSKWPKFNESLII  776
            +F+N   K +K + +  K F+ +++P+APHL+EELW+ +      +    WP ++ES ++
Sbjct  710  VFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLV  769

Query  777  KDKKEIVLQINGKIKDKILLNKEIDEEELKEIAMENGKIKSNL  819
             +  EIV+QI+GK+K K+++ K++  EEL+E+A+ N K+++++
Sbjct  770  ENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEI  812

466) leuS in NC_014387


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  728 bits (2754),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 430/845 (51%), Positives = 613/845 (73%), Gaps = 55/845 (6%)

Query  5    YNHHAVEQKWQKYWKENETFKTDVWDFSKPKYYALDMFPYPSGVGLHAGHPEGYTATDIM  64
            Y+H A+E KWQ +W +N+TFKT+  D SKPK+YALDMFPYPSG GLH GHPEGYTATDI+
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGT-DASKPKFYALDMFPYPSGAGLHVGHPEGYTATDIL  62

Query  65   SRMKRMQGYNVLHPMGYDSFGLPAEQYAVTTGNHPAGFTEKNIETFSKQLRELGFDYDWS  124
            SR KR QG NVLHPMG D+FGLPAEQYA+ TGN+PA FT  NI  F +Q+  LGF YDW 
Sbjct  63   SRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWD  122

Query  125  KMIATSDPKFYKWTQWIFKKLYEAGYAKHIDMPVNWCEELGTVLSNDEVI-DGKSERGGY  183
            + + T+DP++YKWTQWIF KLYE G A + ++PVNW EELGT ++N+EV+ DG SERGGY
Sbjct  123  REVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGY  182

Query  184  PVVKKMMKQWVIDQQAFAEELLDGLNEIDWPESTKEIQRNWIGKSTGVEVDFDIVGGGK-  242
            PVV+K M+QW++   A+AE LL++L+E+DWPES K++QRNWIGKSTG +V F + + +K 
Sbjct  183  PVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  FSIFTTCIETIYGITFMVLAPDGEIVKSLMDRVENPEEVQAYIDETLKKNDLDRTDLNKT  302
            F++FTT  +T++G T+ VLAP+  +V ++    +++E V  Y  ++  K+DL RTDL K 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTS-DQAEAVADYKRQASLKSDLARTDLAKE  301

Query  303  KSGCPLKGIYAINPVNGKEVPLFMGDFVLASYGTGAVMAVPTHDQRDFEYAQVHNLPLIQ  362
            K+G    G YAINPVNGKE+P+ ++D+VLASYGTGA+MAVP+HD+RD E+A+  NL +I 
Sbjct  302  KTGV-WTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  363  VINNTEGTVDVSEHAFEKQDYLGKGCILMNSEEFNGMTVEEAKKGITKKLVDMGVAREKV  422
            V++      +V E AF  ++      + +NS+ ++G+    A   +   L   GV+ E+V
Sbjct  361  VLEGG----NVEEAAFTEDG------LHINSDFLDGLDKASAIAKMVEWLEAEGVGNENV  410

Query  423  NYHFREWIFARQRYWGEPVPCVYKEDGSIVFLDDSELPVVLPELEDYKGR-NGKAPLENA  481
             Y++R+W+F+RQRYWGEP+P +  EDG+   + +SELP+VLP   D +    G +PL N 
Sbjct  411  TYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANV  470

Query  482  TEWKAYDK-NGIKGTRETSTMPGSAGSSWYYMRYIDPDNDNEFANQELLKHWMPVDLYVG  540
            T+W    + +G+KG RET+TMP  AGSSWYY+RYIDP+N + +A++ELLK+W+PVD+YVG
Sbjct  471  TDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVG  530

Query  541  GPEHAVGHLLYSRIWNRFLYNKGLSPVKEPFKKLVHQGMILG------------------  582
            G+EHAV HLLY+R+W++ LY+ G+ P KEPF+KL +QGMILG                  
Sbjct  531  GAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEK  590

Query  583  ---------------ENGIKMGKRFPEFVVNPSDIVRDYGADTLRLYEMFMGPLEVSKPW  627
                           +   KM+K + + VVNP D+V +YGADTLR+YEMFMGPL+ S +W
Sbjct  591  RDGSFFHVETGEELEQAPAKMSKSLKN-VVNPDDVVEQYGADTLRVYEMFMGPLDASIAW  649

Query  628  NSNNVTGARKFINRVYTFFTEPGNITDENNGNLEKIYHQTVKKVTNDFEVLGFNTAIAQM  687
            + + + G+RKF++RVY ++T   +IT+EN+G L+K+Y++TVK VT++ + + FNTAIAQ+
Sbjct  650  SEEGLEGSRKFLDRVYRLIT-TKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQL  708

Query  688  MIFVNAVYKEGSCPREYAENFIKMLSCICPHVGEEIWQIL-GHDNTIAYEPWPTYDESKC  746
            M+FVNA  KE+    +YA  F+++++ + PH+GEE+WQ L + +++I+Y PWP+YDESK 
Sbjct  709  MVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKL  768

Query  747  VEDTVEIAVQINGKVKATLNIGKEDPKDEV--IAKGKELIADKLEGKNIVKEIYVPGRIV  804
            VE+ VEI VQI+GKVKA L ++K+ +++E+  +A ++E +   + GK+I+K I VP ++V
Sbjct  769  VENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLV  828

Query  805  NIVVK  809
            NIV+K
Sbjct  829  NIVIK  833

467) leuS in NC_005364


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  726 bits (2745),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 427/840 (51%), Positives = 606/840 (73%), Gaps = 50/840 (5%)

Query  9    FSHKAIEKKWQKYWKENNIYKTTNNSEK-KAYILDMFPYPSGAGLHVGHIKGYTATDVYS  67
            + H AIE KWQ +W +N+ +KT  ++ K K Y LDMFPYPSGAGLHVGH  GYTATD+ S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  68   RFKRMQGYDVLHPIGWDAFGLPAEQYALKTGNDPREFTLQNIENFKIQLNKMGFSYDYDK  127
            RFKR QG +VLHP+GWDAFGLPAEQYA+ TGNDP EFT +NI NFK Q+N +GFSYD D+
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  128  EINTADPNYYKTTQWIFKQLYKKGLAENRDIDVNWCQELGTVLANDEIIEKDGLMVSERG  187
            E+NT+DPNYYK TQWIF +LY KGLA + ++ VNW +ELGT +AN+E++  +    SERG
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDG---TSERG  180

Query  188  EYPVVKKKMRQWVLKITDYADKLLDGLDNLDWPNSVKELQRNWIGKSEGCEINFKSNDI-  246
             YPVV+K MRQW+LKIT YA++LL++L+++DWP+S+K++QRNWIGKS G ++ FK +D  
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  247  -NIPVFTTRADTIFGVTYIVLASENELVLKLTAPEKLEEVKKYIELTANKSEIERKDESR  305
             ++ VFTTR+DT+FG TY VLA+E+ LV  +T++++ E V  Y   ++ KS++ R D ++
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  306  TKTGVFIGSYATNPLTKEQIQIWISDYVLNDYGSGAIMAVPAHDKRDWDFAAKFNLPIKF  365
             KTGV  GSYA NP+   ++ +WI+DYVL  YG+GAIMAVPAHD RDW+FA +FNL I  
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  366  VIQTKD-QSKAFVGEGIHINSEFLNDLDRIQALQVIHDYVDKNNLGKRKINYKLRDWLFS  424
            V++  + +  AF  +G+HINS+FL++LD+  A+  + + ++ + +G+ ++ Y+LRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  425  RQRFYGEPFPVLYDKDNNIVLIEDNNLPITLPITDYIKPTNTGESPLANVKNWVNVKIGD  484
            RQR+ GEP+P++   D     + +++LP+ LP+T  I+P+ TGESPLANV +W++V   D
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  485  K-EYKRETNTMPQSAASSWYFIAYILANSKNNLIDLTSDEAKKRLEKWLPVDLYIGGQEH  543
                +RETNTMPQ A+SSWY++ YI +++ ++L D         L +WLPVD+Y+GG EH
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLAD------EELLKQWLPVDIYVGGAEH  534

Query  544  AVGHLLYARFWTHFLYDLGLLPTNEPFKRLFNQGMILGPDNR------------------  585
            AV HLLYARFW   LYDLG++PT+EPF++LFNQGMILG   R                  
Sbjct  535  AVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGS  594

Query  586  ---------------KMSKSWGNVINPDDVIDTHGADALRLYEMFMGPLDASLPWSFDGL  630
                           KMSKS  NV+NPDDV++  GAD+LR+YEMFMGPLDAS++WS +GL
Sbjct  595  FFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGL  654

Query  631  DASLKWLNRCYRMINKIEFSNTNNHKLDYVYNDVVKKVTQMIQELKFNTAISQLMVLVNA  690
            ++S K L+R YR+I   E+++ N+  LD VYN+ VK VT+ ++++KFNTAI+QLMV+VNA
Sbjct  655  EGSRKFLDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNA  714

Query  691  IYKEELNTVYKPYIEGFVKMLSLFAPHLSEELWEKL-GNNSSVTLQTWPEFDETKIIKNA  749
              KE+   ++  Y  GFV++++ FAPHL+EELW+ L ++  S++   WP +DE+K++ N 
Sbjct  715  ANKED--KLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVEND  772

Query  750  VVIALQVNGKLRSTIEVEKGTDKETLIKLAQENENIIRFIKDHKNLKYIAVVDRIVNIVI  809
            V I +Q++GK+++ + V K+  +E L  +A  NE++   I +   +K IAV +++VNIVI
Sbjct  773  VEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

468) leuS in NC_010794


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  725 bits (2744),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 454/855 (54%), Positives = 615/855 (72%), Gaps = 66/855 (7%)

Query  7    YPFGVIEPKWQRYWLEKGLFRSADPGEEGSSKPKFYVLDMFPYPSGSGLHVGHLEGYTAS  66
            Y    IEPKWQ +W ++  F+++     ++SKPKFY LDMFPYPSG+GLHVGH EGYTA+
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGT----DASKPKFYALDMFPYPSGAGLHVGHPEGYTAT  59

Query  67   DIIARYKRMKGFNVLHPMGWDAFGLPAEQHAILTGTHPALTTRQNIANFKRQIQAMGFSY  126
            DI++R+KR +G NVLHPMGWDAFGLPAEQ A+ TG +PA  T +NIANFKRQI+A+GFSY
Sbjct  60   DILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSY  119

Query  127  DWSREINTTDPAYYKWTQWIFLRLFEKGLAYVAEAPVWYCPNLKTVLANEEIIHTPDGPR  186
            DW RE+NTTDP YYKWTQWIF +L+EKGLAY AE PV    +L T +ANEE++  PDG  
Sbjct  120  DWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVL--PDGT-  176

Query  187  SERGNHPVIRKPFRQWFLKITAYAEKLLEGLEKVQWPESIKEMQRHWIGKSEGALIRFPV  246
            SERG  PV+RKP RQW LKITAYAE+LLE+LE V+WPESIK+MQR+WIGKS GA + F V
Sbjct  177  SERGGYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKV  236

Query  247  EGKECKIEVFTTRPDTLFGTTFLVLAPEHPLVEEVTTLENKAEVENYRAAAFLKSDLERT  306
             + +  + VFTTRPDTLFG+T+ VLAPEH+LV+ +TT ++   V +Y+  A LKSDL RT
Sbjct  237  KDTDKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLART  296

Query  307  ELAKSKTGVWTGGYALHPVTGERLPIWVSDYVLMTYGTGAIMAVPAHDHRDYEFAKTFNL  366
            +LAK KTGVWTG+YA++PV G  +P+W++DYVL +YGTGAIMAVPAHD+RD EFAK FNL
Sbjct  297  DLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNL  356

Query  367  PIRKVVVPEKDGEQYETGCFTGEGISVDSEFISGLKTAEAKKRIVEWLEERKLGKKTIQY  426
             I    +P  +G + E + FT +G+ ++S+F+ GL  A A  ++VEWLE   +G+  + Y
Sbjct  357  DI----IPVLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTY  412

Query  427  KLRDWLFSRQRYWGEPFPIV-WKEGKAIAVSdadlpvllpdlddftptdEGIAPLSRKKE  485
            +LRDWLFSRQRYWGEP+PI+ W +G + AV++++LP++LP   D+ P++ G +PL+   +
Sbjct  413  RLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTD  472

Query  486  WVELP--DG--TRREINTMPQWAGSCWYYLRYCDPHN-EKLPFSAEKEKYWMSPQGVDLY  540
            W+E+   DG   RRE NTMPQWAGS WYYLRY DPHN EKL+   E  K W++   VD+Y
Sbjct  473  WLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLA-DEELLKQWLP---VDIY  528

Query  541  IGGAEHAVLHLLYARFWHKVLYDIGLVSTPEPFYRLVNQGVILG----------------  584
            +GGAEHAVLHLLYARFWHKVLYD+G+V+T EPF +L NQG+ILG                
Sbjct  529  VGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKV  588

Query  585  -----------------EDNQKMSKSRGNIVNPDAIIQEYGADTLRLFEMFLGPLQQSKP  627
                             +   KMSKS  N+VNPD ++++YGADTLR++EMF+GPL+ S +
Sbjct  589  EKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIA  648

Query  628  WSSKGLEGPHRFLARVWRLFMDEDGEGMWVLRTDIVDEQPPLPIQKLQHKTVAEVTQDIE  687
            WS  GLEG+++FL RV RL+   +           + E+ + +++K+ + TV  VT++++
Sbjct  649  WSEEGLEGSRKFLDRVYRLITTKE-----------ITEENSGALDKVYNETVKAVTEQVD  697

Query  688  NFQFHTAIAKLMTFVNELTKEKTRWKSvlevlllllSPFAPHLCEELWHNL-GHADSLAY  746
            + +F+TAIA+LM FVN   KE          ++ L++PFAPHL EELW+ L + ++S++Y
Sbjct  698  QMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISY  757

Query  747  VPWPEYDPKLLEEQWVEIIVQINGKVRGRLSVKKDTDKQELINRAREHSSIAKWLENRAF  806
            VPWP YD   L E+ VEI+VQI+GKV+++L V KD  ++EL + A  +  +   +  + +
Sbjct  758  VPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDI  817

Query  807  SKIVYIPNKLLNFVF  821
             K++ +PNKL+N+V+
Sbjct  818  IKVIAVPNKLVNIVI  832

469) leuS in NC_021025


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  725 bits (2742),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 427/840 (51%), Positives = 606/840 (73%), Gaps = 50/840 (5%)

Query  3    FSHKAIEKKWQKYWKENNIYKTTNNSEK-KAYILDMFPYPSGAGLHVGHIKGYTATDVYS  61
            + H AIE KWQ +W +N+ +KT  ++ K K Y LDMFPYPSGAGLHVGH  GYTATD+ S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  62   RFKRMQGYDVLHPIGWDAFGLPAEQYALKTGNDPREFTLQNIENFKIQLNKMGFSYDYDK  121
            RFKR QG +VLHP+GWDAFGLPAEQYA+ TGNDP EFT +NI NFK Q+N +GFSYD D+
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  122  EINTADPNYYKTTQWIFKQLYKKGLAENRDIDVNWCQELGTVLANDEIIEKDGLMVSERG  181
            E+NT+DPNYYK TQWIF +LY KGLA + ++ VNW +ELGT +AN+E++  +    SERG
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDG---TSERG  180

Query  182  EYPVVKKKMRQWVLKITDYADKLLDGLDNLDWPNSVKELQRNWIGKSEGCEINFKSNDI-  240
             YPVV+K MRQW+LKIT YA++LL++L+++DWP+S+K++QRNWIGKS G ++ FK +D  
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  241  -NIPVFTTRADTIFGVTYIVLASENELVLKLTAPEKLEEVKKYIELTANKSEIERKDESR  299
             ++ VFTTR+DT+FG TY VLA+E+ LV  +T++++ E V  Y   ++ KS++ R D ++
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  300  TKTGVFIGSYATNPLTKEQIQIWISDYVLNDYGSGAIMAVPAHDKRDWDFAAKFNLPIKF  359
             KTGV  GSYA NP+   ++ +WI+DYVL  YG+GAIMAVPAHD RDW+FA +FNL I  
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  360  VIQTKD-QSKAFVGEGIHINSEFLNDLDRIQALQVIHDYVDKNNLGKRKINYKLRDWLFS  418
            V++  + +  AF  +G+HINS+FL++LD+  A+  + + ++ + +G+ ++ Y+LRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  419  RQRFYGEPFPVLYDKDNNIVLIEDNNLPITLPITDYIKPTNTGESPLANVKNWVNVKIGD  478
            RQR+ GEP+P++   D     + +++LP+ LP+T  I+P+ TGESPLANV +W++V   D
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  479  K-EYKRETNTMPQSAASSWYFIAYILANSKNNLIDLTSDEAKKRLEKWLPVDLYIGGQEH  537
                +RETNTMPQ A+SSWY++ YI +++ ++L D         L +WLPVD+Y+GG EH
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLAD------EELLKQWLPVDIYVGGAEH  534

Query  538  AVGHLLYARFWTHFLYDLGLLPTNEPFKRLFNQGMILGPDNR------------------  579
            AV HLLYARFW   LYDLG++PT+EPF++LFNQGMILG   R                  
Sbjct  535  AVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGS  594

Query  580  ---------------KMSKSWGNVINPDDVIDTHGADALRLYEMFMGPLDASLPWSFDGL  624
                           KMSKS  NV+NPDDV++  GAD+LR+YEMFMGPLDAS++WS +GL
Sbjct  595  FFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGL  654

Query  625  DASLKWLNRCYRMINKIEFSNTNNHKLDYVYNDVVKKVTQMIQELKFNTAISQLMVLVNA  684
            ++S K L+R YR+I   E+++ N+  LD VYN+ VK VT+ ++++KFNTAI+QLMV+VNA
Sbjct  655  EGSRKFLDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNA  714

Query  685  IYKEELNTVYKPYIEGFVKMLSLFAPHLSEELWEKL-GNNSSVTLQTWPEFDETKIIKNA  743
              KE+   ++  Y  GFV++++ FAPHL+EELW+ L ++  S++   WP +DE+K++ N 
Sbjct  715  ANKED--KLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVEND  772

Query  744  VVIALQVNGKLRSTIEVEKGTDKETLIKLAQENENIIRFIKDHKNLKYIAVVDRIVNIVI  803
            V I +Q++GK+++ + V K+  +E L  +A  NE++   I +   +K IAV +++VNIVI
Sbjct  773  VEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

470) leuS in NC_014225


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  724 bits (2740),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 445/837 (54%), Positives = 605/837 (73%), Gaps = 28/837 (3%)

Query  21   TFKVDVDPNKPKYYVLDMFPYISGAGLHVGHVLGYTATDILARYKRQLGFNVLHPMGWDS  80
            TFK + D++KPK+Y LDMFPY SGAGLHVGH  GYTATDIL+R+KR  G NVLHPMGWD+
Sbjct  22   TFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSRFKRAQGHNVLHPMGWDA  81

Query  81   FGLPAEQHAIRTGTHPAETTEINLANFRKQLKSLGFSYDWDREFGTHEPTYYKWTQWIFT  140
            FGLPAEQ A+ TG +PAE T  N+ANF++Q+++LGFSYDWDRE  T +P YYKWTQWIFT
Sbjct  82   FGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFT  141

Query  141  KLFEKGLAYEAEMPVNWCPALGTVLANeeveegkskeggh-evIRRPLRQWVLKITdyad  199
            KL+EKGLAYEAE+PVNW   LGT +ANEEV  + + E G   V+R+P+RQW+LKIT YA+
Sbjct  142  KLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAE  201

Query  200  rllkdldlldWPESLKRLQKNWIGRSEGAQVKFPVNGTKHLLSVFTTRPDTLFGATYMVL  259
            RLL DL+ +DWPES+K +Q+NWIG+S GA+V F V++T   ++VFTTRPDTLFGATY VL
Sbjct  202  RLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVL  261

Query  260  APEHPLVSEIAADSCKEAVETYQRQAAMKSDMDRTDFSREKTGVFTGAYAINPANGREIP  319
            APEH+LV  I++    EAV  Y+RQA++KSD+ RTD+++EKTGV TG+YAINP NG+E+P
Sbjct  262  APEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAINPVNGKEMP  321

Query  320  IWISDYVLIGYGTGAIMAVPSHDQRDFDFARAHHLEVIPVFDPNIESHPELVPETLSHDE  379
            +WI+DYVL +YGTGAIMAVP+HD+RD +FA+  +L++IPV++     ++ +         
Sbjct  322  VWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEAAFT--------  373

Query  380  LRELVIAGKHCWEGEGVCINSANEEVSLNGLRVKEAVEKMLAWLEKKGYGKKTVSYKLRD  439
                          +G+ INS      L+GL    A+ KM+ WLE  G G+  V+Y+LRD
Sbjct  374  -------------EDGLHINSD----FLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  440  WLFSRQRYWGEPFPILHLADGTKRVLELDELPLTPPNLSDFKPAGDGQSPIAKVDDWVNI  499
            WLFSRQRYWGEP+PI+H  DGT   +   ELPL  P   D++P+G G+SP+A+V DW+++
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  500  ADPKSGQQAKRETNTMPQWAGSCWYYLRFCDPHNHDEAWSREAENYWMPVDLYVGGVEHA  559
            +    G +++RETNTMPQWAGS WYYLR+ DPHN +     E  + W+PVD+YVGG EHA
Sbjct  477  T-REDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  560  VLHLLYARFWHKVLYDTGYVSTPEPFQSLRNQGLIVSRSFKDSGNNYVPTALVKEKDGAY  619
            VLHLLYARFWHKVLYD G V+T EPFQ L NQG+I++ S++DS    V+T  V  +DG++
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSF  595

Query  620  FHKETGEELTSQIEKMSKSKLNGVVPDEIIAEYGADALRLYEMFMGPLDKEKVWNTDAVN  679
            FH ETGEEL     KMSKS  N V PD+++ +YGAD+LR+YEMFMGPLD    W+ ++++
Sbjct  596  FHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLE  655

Query  680  GCRRFLQRFYDACASDKVTDIDHEDALKLGHRLVHDVSKDIEQMSFNTSVARFMEFMNDL  739
            G R+FL+R Y   ++  +T+ +     K+ +  V  V+ +++QM FNT++A++M F+N  
Sbjct  656  GSRKFLDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAA  715

Query  740  SKLEAYPRSVMKMAIQTLAPFAPHLAEETWEMLGFKEELSRCL-WPEVDPKYLKNDRVTY  798
            +K +       K  +Q +APFAPHL+EE W+ L    E    + WP  D   L ++ V  
Sbjct  716  NKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEI  775

Query  799  VVQVNGKVRGRLEMDKGLSKEDLMEYAVSDPHVVKFLDGKEIRKVIFVPDKLLNLVV  855
            VVQ++GKV+++L + K+LS+E+L E A+++  V   + GK+I KVI VP+KL+N+V+
Sbjct  776  VVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

471) leuS in NC_008639


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  723 bits (2736),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 433/848 (52%), Positives = 608/848 (72%), Gaps = 58/848 (6%)

Query  3    YDFSTIEKKWQSFWLKNNSFSSGESTDKPKYYVLDMFPYPSGSGLHVGHLEGYTATDIVA  62
            YD ++IE KWQ+FW  N++F +G  + KPK+Y LDMFPYPSG+GLHVGH EGYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRSCGYNVLHPMGWDAFGLPAEQFAIKTGTHPKNTTEKNISSFRETLQAMGFSYDWSR  122
            R+KR+ G NVLHPMGWDAFGLPAEQ+A+ TG +P + T  NI++F+  ++A+GFSYDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EINTTSPDYFRWTQWIFIKLYELGLAYVSEVDINWCEELKTVLANEEV---EEKVKEGYT  179
            E+NTT P+Y++WTQWIF KLYE GLAY +EV +NW EEL T +ANEEV       + GY 
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  180  VIRKPLRQWVLKITAYAERllddldeldWPENVKQMQRNWIGRSEGMEIDFELRCHNRKL  239
            V+RKP+RQW+LKITAYAERLL+DL+E+DWPE++K+MQRNWIG+S G ++ F ++  ++ +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  240  RVYTTRPDTLFGATFLVISPEHPLALKLATAQQLVAVTQYIKEAKLKSELERTGLQKDKT  299
             V+TTRPDTLFGAT+ V++PEH+L   ++T++Q  AV++Y ++A LKS+L RT+L K+KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  300  GIFTGSFAINPATGDPLPVWISDFVLTSYGTGAIMSVPAHDSRDWEFAKKFGLPIIEVIK  359
            G+ TGS+AINP  G  +PVWI+D+VL+SYGTGAIM+VPAHD RDWEFAK+F L II V+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  360  SPDGVDDAAFEGKESVSINSSNPEISIDGLHFSEAFQIMAHWLETKGLGERKVTYKLRDW  419
            + + V++AAF   +++ INS      +DGL+ + A+  M +WLE+ G+G+ +VTY+LRDW
Sbjct  364  GGN-VEEAAF-TEDGLHINSD----FLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDW  417

Query  420  IFSRQRYWGEPIPVKHYEDGSIRT--ESNLPLQLPEVEAYQPSETGESPLATMHDWLYGA  477
            +FSRQRYWGEPIP+ H EDG+  +  ES+LPL LP     +PS TGESPLA + DWL  +
Sbjct  418  LFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT  477

Query  478  DEFG-SFRRETNTMPQWAGSCWYYLRFIDPENNAQLIDPAKEKYWMNVDLYIGGAEHAVL  536
             E G   RRETNTMPQWAGS WYYLR+IDP+N  +L D    K W+ VD+Y+GGAEHAVL
Sbjct  478  REDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVL  537

Query  537  HLLYARFWHKVLYDLGVVSSREPFKKLFNQGMILG-------------------------  571
            HLLYARFWHKVLYDLGVV+++EPF+KLFNQGMILG                         
Sbjct  538  HLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFH  597

Query  572  --------EDNEKMSKSRGNVIPADQVLKDYGADAVRLYEMFLGPLEQVKPWNTNGIEGI  623
                    +   KMSKS  NV+ +D+V+ +YGAD++R+YEMF+GPL+   +W+ +G+EG 
Sbjct  598  VETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGS  657

Query  624  SRFLGKVWRLVYPDSENPDQRDQAAVLDENPLPEILQRRMHKTIKKVTEDTDHLKFNTAI  683
             +FL++V RL+       ++            +  L++  + T+K VTE+ D++KFNTAI
Sbjct  658  RKFLDRVYRLITTKEITEEN------------SGALDKVYNETVKAVTEQVDQMKFNTAI  705

Query  684  SEMMVFVNELQKNGCRQKSAVENLLLMLAPYAPHITAELWQAIGHTS-PISAEPFPVFDP  742
            +++MVFVN  +K++         ++ ++AP+APH+  ELWQA+  ++ +IS  P P +D 
Sbjct  706  AQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDE  765

Query  743  AIAEDPVVTIAVQVNGKLRGRFTAPAKSPEESLVDMAKHVDTVIKFLEGQTIVKEIVIQD  802
            +   +  V I VQ++GK+++++  +   + E L ++A   + V   + G+ I+K I + +
Sbjct  766  SKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPN  825

Query  803  KLVNFAVK  810
            KLVN+ +K
Sbjct  826  KLVNIVIK  833

472) leuS in NC_010673


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  722 bits (2730),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 455/845 (54%), Positives = 630/845 (75%), Gaps = 15/845 (1%)

Query  1    MSEYNFTKIEKKWQDYWDKHKTYKVNEDPNIPKEKRIYILDMFPYPSANGLHVGHPEGYT  60
            M+ Y+ T IE KWQ +W  + T+K   D++ PK   +Y LDMFPYPS+ GLHVGHPEGYT
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPK---FYALDMFPYPSGAGLHVGHPEGYT  57

Query  61   ATDILTRYKLLNGFNVLHPIGFDSFGLPAENYAIQTGEHPkkiteknikkfkeQIKALGF  120
            ATDIL+R+K  +G NVLHP+G D+FGLPAE+YA++TG++P  +T  NI +FK QI+ALGF
Sbjct  58   ATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGF  117

Query  121  AYDWDREIRTHDENYYKWTQWIFLKLYKKGLAYTKEMPVWYCPDLGTVLSNEEVIQTPDG  180
            +YDWDRE+ T D NYYKWTQWIF KLY KGLAY  E+PV    +LGT ++NEEV+  PDG
Sbjct  118  SYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVL--PDG  175

Query  181  PRSERGFHKVKRKPLRQWILKITEYAERLIKDLEEIDWPESVKEMQKNWIGKSTGAEIEF  240
              SERG   V RKP+RQW+LKIT YAERL+ DLEE+DWPES+K+MQ+NWIGKSTGA++ F
Sbjct  176  T-SERGGYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTF  234

Query  241  SVKASKEKIKVFTTRPDTIFGVTYLVLAPEHSIVDKITKDEFKPMIVEYRERETLKSDLE  300
             VK +   + VFTTRPDT+FG TY VLAPEH++VD IT  +    + +Y+ + +LKSDL 
Sbjct  235  KVKDTDKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLA  294

Query  301  RTSLEKDKTGVFTGAYAINPITGEEIPIWIGSYILGTYGTGAVMSVPAHDARDFEFAKKY  360
            RT L K+KTGV TG+YAINP+ G E+P+WI+ Y+L++YGTGA+M+VPAHD RD EFAK++
Sbjct  295  RTDLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQF  354

Query  361  NLPIKQVVSQTGNNEILTQPFTENGISINTPEEF-NNLKTDEIKERVIKWLTENKKGQKK  419
            NL I  V+     +E    +FTE+G+ IN+  +F + L       +++ WL  +  G+ +
Sbjct  355  NLDIIPVLEGGNVEE---AAFTEDGLHINS--DFLDGLDKASAIAKMVEWLEAEGVGNEN  409

Query  420  VNYKLRDWIFSRQRYWGepipiildddlneipleedelplrlpeieNYKPSGTGESPLSR  479
            V Y+LRDW+FSRQRYWGEPIPII  +D    ++ E ELPL LP   + +PSGTGESPL+ 
Sbjct  410  VTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLAN  469

Query  480  IQDWVNIKR-NGKTYKRETNTMPQWAGSCWYYIRYLDPNNDNEFASKEKINYWMPVDLYI  538
            + DW+++ R +G   +RETNTMPQWAGS WYY+RY+DP+N + +A  E ++ W+PVD+Y+
Sbjct  470  VTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYV  529

Query  539  GGAEHSVLHLLYARFWHKVLYDLGYVNTKEPFKKLINQGMITSFAYQDENGILIPNDEVe  598
            GGAEH+VLHLLYARFWHKVLYDLG V TKEPF+KL+NQGMI + +Y+D  G L++ D VE
Sbjct  530  GGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVE  589

Query  599  kkdnkffskknnkelkQIVAKMSKSLKNIINPDDIIKEYGADSMRIYEMFMGPLTDSKPW  658
            K+D  FF      EL Q  AKMSKSLKN++NPDD++ +YGAD++R+YEMFMGPL  S +W
Sbjct  590  KRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAW  649

Query  659  NTQGLIGIFRFLNKI-WTIKNKELTKESASKEIISELHKTIKKVTEDIENLNFNTAISSL  717
            + +GL G  +FL+++ + I  KE+T E+++  +    + T+K VTE++++++FNTAI+ L
Sbjct  650  SEEGLEGSRKFLDRVYRLITTKEITEENSG-ALDKVYNETVKAVTEQVDQMKFNTAIAQL  708

Query  718  MIFINELLKHDKNYLEIFKPLTIILSPFAPHLGEELWEYMGETPSIFKSAKWPEYDPNLI  777
            M+F+N   K+DK + +  K +  +++PFAPHLGEELW+ +  +   +    WP YD + +
Sbjct  709  MVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKL  768

Query  778  IDNTREIVLQINGKIKDKIILNKGTNEEALKSIALknhkimqniqnkqiikiiTVKDKLI  837
            ++N  EIV+QI+GK+K K+++ K+ + E L+ +AL N+K+  +I  K+IIK+I+V +KL+
Sbjct  769  VENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLV  828

Query  838  NIVTR  842
            NIV +
Sbjct  829  NIVIK  833

473) leuS in NC_017418


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  722 bits (2733),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 416/815 (52%), Positives = 600/815 (74%), Gaps = 15/815 (1%)

Query  1    MSKYEFIKIEKKWQEFWDNNKTYKVEEDPSIPKEKRLYILDMFPYPSANGLHVGHPEGYT  60
            M+ Y+   IE KWQ FW +N T+K   D+S PK   +Y LDMFPYPS+ GLHVGHPEGYT
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPK---FYALDMFPYPSGAGLHVGHPEGYT  57

Query  61   ATDIFGRYKLLNGFHVLHPIGFDSFGLPAENYAIQTGTHPQKSTEENINKFKKQIKALGF  120
            ATDI++R+K  +G +VLHP+G D+FGLPAE+YA++TG +P   T ENI +FK+QI+ALGF
Sbjct  58   ATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGF  117

Query  121  AYDWDREIRTHEENYYKWTQWIFLQLYKKGLAYVKEMPVWYCPELGTVLANEEIIQTSDG  180
            +YDWDRE+ T + NYYKWTQWIF +LY KGLAY  E+PV    ELGT +ANEE++  +  
Sbjct  118  SYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDG--  175

Query  181  PKSERGSYSVEKKYLRQWVLKITKYAerllddleeleWPESVKEMQRNWIGKSTGVEIEF  240
              SERG+Y+V +K +RQW+LKIT YAERLL+DLEE++WPES+K+MQRNWIGKSTG ++ F
Sbjct  176  -TSERGGYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTF  234

Query  241  KIEGHNDKIKVFTTRPDTIFGITYLVIAPENKLIEKITKNNFKQNVLKYVKREELKSDLN  300
            K+ + +  + VFTTRPDT+FG TY V+APE+ L++ IT ++  + V  Y ++  LKSDL 
Sbjct  235  KVKDTDKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLA  294

Query  301  RTSLEKDKSGVFTGSYAFHPITNEKIPIWVGSYVLGTYGTGAVMGVPAHDERDFQFAKKY  360
            RT L K+K+GV TGSYA++P+    +P+W++ YVL++YGTGA+M+VPAHDERD +FAK++
Sbjct  295  RTDLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQF  354

Query  361  QLKILPVISKSGKNEILEKAFVDDGISINSPNEF-NNLKNSEVKDKVIKWLTKNKKGKEK  419
            +L I+PV+  +   ++ E AF +DG+ INS  +F + L ++    K++ WL  +  G+E+
Sbjct  355  NLDIIPVLEGG---NVEEAAFTEDGLHINS--DFLDGLDKASAIAKMVEWLEAEGVGNEN  409

Query  420  VAYKLRDWIFSRQRYWGEPIPILFDKLGNTIPLEENDLPLKLPEIANYKPSGTGESPLSR  479
            V+Y+LRDW+FSRQRYWGEPIPI+    G + ++ E++LPL LP   + +PSGTGESPL+ 
Sbjct  410  VTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLAN  469

Query  480  IKDWVNV-KDMGFT--RETNTMPQWAGSCWYYLRYLDPKNSKEFANKKKIEYWMPVDLYI  536
            + DW++V ++ G    RETNTMPQWAGS WYYLRY+DP N+  +A+   +  W+PVD+Y+
Sbjct  470  VTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYV  529

Query  537  GGAEHTVLHLLYSRFWHKVLYDLGYVNTKEPFKKLINQGIITSFSYQKENGVLIPNDQVI  596
            GGAEH+VLHLLY+RFWHKVLYDLG V TKEPF+KL+NQG+I + SY+   G L++ D+V 
Sbjct  530  GGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVE  589

Query  597  EkdnkffdkkdnkEVTQVIAKMSKSLKNVINPDDIIKEFGADSMRIYEMFMGPLTDSKPW  656
             +D  FF+     E+ Q  AKMSKSLKNV+NPDD++ ++GAD++R+YEMFMGPL  S +W
Sbjct  590  KRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAW  649

Query  657  NTKGIIGVFRFLNKIWNLREKELSKDNPPKEITSELHKVIKKVTEDTEKLNFNTAISAMM  716
            +  G+ G  +FL+++  L       ++ +  +    +  +K VTE+ ++++FNTAI+ +M
Sbjct  650  SEEGLEGSRKFLDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLM  709

Query  717  IFINELLKYEKNYLNIFKPFIIILSPYAPHLAEELWEYIGELPSLFKNSKWPKFDESLII  776
            +F+N   K +K + +  K F+ +++P+APHL+EELW+ +      +    WP +DES ++
Sbjct  710  VFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLV  769

Query  777  KDKKEIVLQINGKIKDKILLNKETDEKELKDIAME  811
             +  EIV+QI+GK+K K+++ K+    EL+++A+ 
Sbjct  770  ENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALA  804

474) leuS in NC_007633


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  722 bits (2732),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 433/840 (52%), Positives = 601/840 (72%), Gaps = 50/840 (5%)

Query  3    FSHKAIEKKWQKYWKENNVYKT-TDSNHKKAYVLDMFPYPSGAGLHVGHIKGYTATDVYS  61
            + H AIE KWQ +W +N+ +KT TD++  K Y LDMFPYPSGAGLHVGH  GYTATD+ S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  62   RFKRMQGYDVLHPIGWDAFGLPAEQYALKTGNDPRDFTLKNIENFKAQLVKMGFSYDYDK  121
            RFKR QG +VLHP+GWDAFGLPAEQYA+ TGNDP +FT  NI NFK Q+  +GFSYD D+
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  122  EINTADPNYYKVTQWIFKELYKKGLAENRNIDVNWCQELGTVLANDEIIEKDGLMVSERG  181
            E+NT+DPNYYK TQWIF  LY KGLA + ++ VNW +ELGT +AN+E++  +    SERG
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDG---TSERG  180

Query  182  EYPVVKKKMRQWVLKITDYADKLLKGLDNLDWPNSVKELQRNWIGKSEGCEINFKSNDI-  240
             YPVV+K MRQW+LKIT YA++LL +L+++DWP+S+K++QRNWIGKS G ++ FK +D  
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  241  -NIPVFTTRADTVFGATYIVLAPENELVLKLTTPNKLDEVKKYIELTANKSEIERKDESK  299
             ++ VFTTR+DT+FGATY VLAPE+ LV  +TT+++ + V  Y   ++ KS++ R D +K
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  300  TKTGVFIGSYAINPLTKEQIQIWISDYVLNDYGSGAIMAVPAHDKRDWDFATKFNLPIRF  359
             KTGV  GSYAINP+   ++ +WI+DYVL  YG+GAIMAVPAHD RDW+FA +FNL I  
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  360  VISTKD-ESKAFVGEGKHINSEFLNDLDRIQSLQVIHDYIEKNNLGKKKTNYKLRDWLFS  418
            V+   + E  AF  +G HINS+FL++LD+  ++  + + +E + +G+ +  Y+LRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  419  RQRFYGEPFPVLYDKDNNIILVEDDDLPITLPKTDYIKPTNTGESPLANVKNWVNV-KIG  477
            RQR+ GEP+P++   D     V + +LP+ LP T  I+P+ TGESPLANV +W++V + +
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  478  DREYKRETNTMPQSAGSSWYFIAYILANSKNNLIDLTSDEAKKRLEKWLPVDLYIGGQEH  537
            +   +RETNTMPQ AGSSWY++ YI +++ ++L D         L +WLPVD+Y+GG EH
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLAD------EELLKQWLPVDIYVGGAEH  534

Query  538  AVGHLLYSRFWTHFLYDLGLLPTSEPFQRLFNQGMILGPDNR------------------  579
            AV HLLY+RFW   LYDLG++PT EPFQ+LFNQGMILG   R                  
Sbjct  535  AVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGS  594

Query  580  ---------------KMSKSWGNVINPDDVIDTHGADALRLYEMFMGPLDASLPWSFDGL  624
                           KMSKS  NV+NPDDV++  GAD+LR+YEMFMGPLDAS++WS +GL
Sbjct  595  FFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGL  654

Query  625  DASLKWLNRCYRMINKIEFSNTNNHKLDYVYNDVVKKVTQMITELKFNTAISQLMVLVNA  684
            ++S K L+R YR+I   E+++ N+  LD VYN+ VK VT+ + ++KFNTAI+QLMV+VNA
Sbjct  655  EGSRKFLDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNA  714

Query  685  IYKEELSTVYKPYIEGFVKMLSLFSPHLAEELWEKL-GNNSSVTLQAWPEFDETKIVKNT  743
              KE+   ++  Y  GFV++++ F+PHL+EELW+ L ++  S++  +WP +DE+K+V N 
Sbjct  715  ANKED--KLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVEND  772

Query  744  VVIALQVNGKLRSTIEVEKGTDKETLIKLAQENENIIRFIKGHKNLKYIAVVDRIVNIVI  803
            V I +Q++GK+++ + V K+  +E L  +A  NE++   I G   +K IAV +++VNIVI
Sbjct  773  VEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

475) leuS in NC_015921


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  720 bits (2723),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 422/823 (52%), Positives = 603/823 (74%), Gaps = 15/823 (1%)

Query  1    MSKYEFIKIEKKWQEFWDNNKTYKVEEDPNIPKEKRLYILDMFPYPSANGLHVGHPEGYT  60
            M+ Y+   IE KWQ FW +N T+K   D++ PK   +Y LDMFPYPS+ GLHVGHPEGYT
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPK---FYALDMFPYPSGAGLHVGHPEGYT  57

Query  61   ATDIFGRYKLLNGFHVLHPIGFDSFGLPAENYAIQTGTHPQKSTEENINKFKKQIKALGF  120
            ATDI++R+K  +G +VLHP+G D+FGLPAE+YA++TG +P   T ENI +FK+QI+ALGF
Sbjct  58   ATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGF  117

Query  121  AYDWDREIRTHEENYYKWTQWIFLQLYKKGLAYVKEMPVWYCPELGTVLANEEIIQTPDG  180
            +YDWDRE+ T + NYYKWTQWIF +LY KGLAY  E+PV    ELGT +ANEE++  PDG
Sbjct  118  SYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVL--PDG  175

Query  181  PKSERGFYKVEKKYLKQWVLKITKYAerllddleeleWPESVKEMQRNWIGKSTGVEIDF  240
              SERG Y V +K ++QW+LKIT YAERLL+DLEE++WPES+K+MQRNWIGKSTG ++ F
Sbjct  176  T-SERGGYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTF  234

Query  241  EIEGHSDKIKVFTTRPDTIFGITYLVIAPENKLIEKITKNNFKKDVLKYVKHEELKSDLK  300
             + +    + VFTTRPDT+FG TY V+APE+ L++ IT ++    V  Y ++  LKSDL 
Sbjct  235  KVKDTDKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLA  294

Query  301  RTSLEKDKSGVFTGSYAFHPITNEKIPIWVGSYVLGTYGTGAVMGVPAHDERDFQFAKKY  360
            RT L K+K+GV TGSYA++P+    +P+W++ YVL++YGTGA+M+VPAHDERD +FAK++
Sbjct  295  RTDLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQF  354

Query  361  QLKILPVISKSGKNEILEKAFINDGISINSPNEF-NNLKNSEVKEKVIEWLTKNKKGKEK  419
            +L I+PV+  +   ++ E AF +DG+ INS  +F + L ++    K++EWL  +  G+E+
Sbjct  355  NLDIIPVLEGG---NVEEAAFTEDGLHINS--DFLDGLDKASAIAKMVEWLEAEGVGNEN  409

Query  420  VTYRLRDWIFSRQRYWGEPIPILFDKLGNAIPLEENDLPLKLPEIANYKPSGTGESPLSR  479
            VTYRLRDW+FSRQRYWGEPIPI+    G + ++ E++LPL LP   + +PSGTGESPL+ 
Sbjct  410  VTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLAN  469

Query  480  IKDWVNVK---EMDLTRETNTMPQWAGSCWYYLRYLDPKNPKEFANKKKIEYWMPVDLYI  536
            + DW++V     +   RETNTMPQWAGS WYYLRY+DP N   +A+   +  W+PVD+Y+
Sbjct  470  VTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYV  529

Query  537  GGAEHTVLHLLYSRFWHKVLYDLGYVNTKEPFKKLINQGIITSFSYQKENGVLIPNDQvv  596
            GGAEH+VLHLLY+RFWHKVLYDLG V TKEPF+KL+NQG+I + SY+   G L++ D+V 
Sbjct  530  GGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVE  589

Query  597  ekdnkffdkkdnkevTQVIAKMSKSLKNVINPDDIIKEFGADSMRIYEMFMGPLTDSKPW  656
             +D  FF+     E+ Q  AKMSKSLKNV+NPDD++ ++GAD++R+YEMFMGPL  S +W
Sbjct  590  KRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAW  649

Query  657  NTKGIIGVFRFLNKIWNLREKELSKDNPPKEIISELHKVIKKVTEDTENLNFNTAISAMM  716
            +  G+ G  +FL+++  L       ++ +  +    +  +K VTE+ ++++FNTAI+ +M
Sbjct  650  SEEGLEGSRKFLDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLM  709

Query  717  IFINELLKYEKNYLNIFKPFIIILSPYAPHLAEELWEYIGELPSLFKNSKWPKFDESLII  776
            +F+N   K +K + +  K F+ +++P+APHL+EELW+ +      +    WP +DES ++
Sbjct  710  VFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLV  769

Query  777  KDKKEIVLQINGKIKDKILLNKETDEEELKEIAMENSKIKSNL  819
             +  EIV+QI+GK+K K+++ K+   EEL+E+A+ N K+++++
Sbjct  770  ENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEI  812

476) leuS in NC_022048


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  720 bits (2724),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 417/815 (52%), Positives = 599/815 (74%), Gaps = 15/815 (1%)

Query  1    MSKYEFIKIEKKWQEFWDNNKTYKVEEDPSIPKEKRLYILDMFPYPSANGLHVGHPEGYT  60
            M+ Y+   IE KWQ FW +N T+K   D+S PK   +Y LDMFPYPS+ GLHVGHPEGYT
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPK---FYALDMFPYPSGAGLHVGHPEGYT  57

Query  61   ATDIFGRYKLLNGFHVLHPIGFDSFGLPAENYAIQTGTHPQKSTEENINKFKKQIKALGF  120
            ATDI++R+K  +G +VLHP+G D+FGLPAE+YA++TG +P   T ENI +FK+QI+ALGF
Sbjct  58   ATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGF  117

Query  121  AYDWDREIRTHEENYYKWTQWIFLQLYKKGLAYVKEMPVWYCPELGTVLANEEIIQTSDG  180
            +YDWDRE+ T + NYYKWTQWIF +LY KGLAY  E+PV    ELGT +ANEE++  +  
Sbjct  118  SYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDG--  175

Query  181  PKSERGSYSVEKKYLRQWVLKITKYAerllddleeleWPESVKEMQRNWIGKSTGVEIEF  240
              SERG+Y+V +K +RQW+LKIT YAERLL+DLEE++WPES+K+MQRNWIGKSTG ++ F
Sbjct  176  -TSERGGYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTF  234

Query  241  EIEGHSDKIKVFTTRPDTIFGITYLVIAPENKLIEKITKNNFKQNVLKYVKHEELKSDLN  300
             + +    + VFTTRPDT+FG TY V+APE+ L++ IT ++  + V  Y ++  LKSDL 
Sbjct  235  KVKDTDKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLA  294

Query  301  RTSLEKDKSGVFTGSYAFHPITNEKIPIWVGSYVLGTYGTGAVMGVPAHDERDFQFAKKY  360
            RT L K+K+GV TGSYA++P+    +P+W++ YVL++YGTGA+M+VPAHDERD +FAK++
Sbjct  295  RTDLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQF  354

Query  361  QLKILPVISKSGKNEILEKAFVDDGISINSPNEF-NNLKNSEVKDKVIKWLTKNKKGKEK  419
            +L I+PV+  +   ++ E AF +DG+ INS  +F + L ++    K++ WL  +  G+E+
Sbjct  355  NLDIIPVLEGG---NVEEAAFTEDGLHINS--DFLDGLDKASAIAKMVEWLEAEGVGNEN  409

Query  420  VAYKLRDWIFSRQRYWGEPIPILFDKLGNAIPLEENDLPLKLPEIANYKPSGTGESPLSR  479
            V+Y+LRDW+FSRQRYWGEPIPI+    G + ++ E++LPL LP   + +PSGTGESPL+ 
Sbjct  410  VTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLAN  469

Query  480  IKDWVNV-KDMGFT--RETNTMPQWAGSCWYYLRYLDPKNSKEFANKKKIEYWMPVDLYI  536
            + DW++V ++ G    RETNTMPQWAGS WYYLRY+DP N+  +A+   +  W+PVD+Y+
Sbjct  470  VTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYV  529

Query  537  GGAEHTVLHLLYSRFWHKVLYDLGYVNTKEPFKKLINQGIITSFSYQKENGVLIPNDQVI  596
            GGAEH+VLHLLY+RFWHKVLYDLG V TKEPF+KL+NQG+I + SY+   G L++ D+V 
Sbjct  530  GGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVE  589

Query  597  EkdnkffdkkdnkEVTQVIAKMSKSLKNVINPDDIIKEFGADSMRIYEMFMGPLTDSKPW  656
             +D  FF+     E+ Q  AKMSKSLKNV+NPDD++ ++GAD++R+YEMFMGPL  S +W
Sbjct  590  KRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAW  649

Query  657  NTKGIIGVFRFLNKIWNLREKELSKENPPREIISELHKVIKKVTEDTEKLNFNTAISAMM  716
            +  G+ G  +FL+++  L       E+ +  +    +  +K VTE+ ++++FNTAI+ +M
Sbjct  650  SEEGLEGSRKFLDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLM  709

Query  717  IFINELLKYEKNYLNIFKPFIIILSPYAPHLAEELWEYIGELPSLFKNSKWPKFDESLII  776
            +F+N   K +K + +  K F+ +++P+APHL+EELW+ +      +    WP +DES ++
Sbjct  710  VFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLV  769

Query  777  KDKKEIVLQINGKIKDKILLNKETGEKELKEIAME  811
             +  EIV+QI+GK+K K+++ K+ +  EL+E+A+ 
Sbjct  770  ENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALA  804

477) leuS in NC_011728


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  720 bits (2724),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 417/815 (52%), Positives = 599/815 (74%), Gaps = 15/815 (1%)

Query  1    MSKYEFIKIEKKWQEFWDNNKTYKVEEDPSIPKEKRLYILDMFPYPSANGLHVGHPEGYT  60
            M+ Y+   IE KWQ FW +N T+K   D+S PK   +Y LDMFPYPS+ GLHVGHPEGYT
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPK---FYALDMFPYPSGAGLHVGHPEGYT  57

Query  61   ATDIFGRYKLLNGFHVLHPIGFDSFGLPAENYAIQTGTHPQKSTEENINKFKKQIKALGF  120
            ATDI++R+K  +G +VLHP+G D+FGLPAE+YA++TG +P   T ENI +FK+QI+ALGF
Sbjct  58   ATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGF  117

Query  121  AYDWDREIRTHEENYYKWTQWIFLQLYKKGLAYVKEMPVWYCPELGTVLANEEIIQTSDG  180
            +YDWDRE+ T + NYYKWTQWIF +LY KGLAY  E+PV    ELGT +ANEE++  +  
Sbjct  118  SYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDG--  175

Query  181  PKSERGSYSVEKKYLRQWVLKITKYAerllddleeleWPESVKEMQRNWIGKSTGVEIEF  240
              SERG+Y+V +K +RQW+LKIT YAERLL+DLEE++WPES+K+MQRNWIGKSTG ++ F
Sbjct  176  -TSERGGYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTF  234

Query  241  EIEGHSDKIKVFTTRPDTIFGITYLVIAPENKLIEKITKNNFKQNVLKYVKHEELKSDLN  300
             + +    + VFTTRPDT+FG TY V+APE+ L++ IT ++  + V  Y ++  LKSDL 
Sbjct  235  KVKDTDKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLA  294

Query  301  RTSLEKDKSGVFTGSYAFHPITNEKIPIWVGSYVLGTYGTGAVMGVPAHDERDFQFAKKY  360
            RT L K+K+GV TGSYA++P+    +P+W++ YVL++YGTGA+M+VPAHDERD +FAK++
Sbjct  295  RTDLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQF  354

Query  361  QLKILPVISKSGKNEILEKAFVDDGISINSPNEF-NNLKNSEVKDKVIKWLTKNKKGKEK  419
            +L I+PV+  +   ++ E AF +DG+ INS  +F + L ++    K++ WL  +  G+E+
Sbjct  355  NLDIIPVLEGG---NVEEAAFTEDGLHINS--DFLDGLDKASAIAKMVEWLEAEGVGNEN  409

Query  420  VAYKLRDWIFSRQRYWGEPIPILFDKLGNAIPLEENDLPLKLPEIANYKPSGTGESPLSR  479
            V+Y+LRDW+FSRQRYWGEPIPI+    G + ++ E++LPL LP   + +PSGTGESPL+ 
Sbjct  410  VTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLAN  469

Query  480  IKDWVNV-KDMGFT--RETNTMPQWAGSCWYYLRYLDPKNSKEFANKKKIEYWMPVDLYI  536
            + DW++V ++ G    RETNTMPQWAGS WYYLRY+DP N+  +A+   +  W+PVD+Y+
Sbjct  470  VTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYV  529

Query  537  GGAEHTVLHLLYSRFWHKVLYDLGYVNTKEPFKKLINQGIITSFSYQKENGVLIPNDQVI  596
            GGAEH+VLHLLY+RFWHKVLYDLG V TKEPF+KL+NQG+I + SY+   G L++ D+V 
Sbjct  530  GGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVE  589

Query  597  EkdnkffdkkdnkEVTQVIAKMSKSLKNVINPDDIIKEFGADSMRIYEMFMGPLTDSKPW  656
             +D  FF+     E+ Q  AKMSKSLKNV+NPDD++ ++GAD++R+YEMFMGPL  S +W
Sbjct  590  KRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAW  649

Query  657  NTKGIIGVFRFLNKIWNLREKELSKENPPREIISELHKVIKKVTEDTEKLNFNTAISAMM  716
            +  G+ G  +FL+++  L       E+ +  +    +  +K VTE+ ++++FNTAI+ +M
Sbjct  650  SEEGLEGSRKFLDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLM  709

Query  717  IFINELLKYEKNYLNIFKPFIIILSPYAPHLAEELWEYIGELPSLFKNSKWPKFDESLII  776
            +F+N   K +K + +  K F+ +++P+APHL+EELW+ +      +    WP +DES ++
Sbjct  710  VFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLV  769

Query  777  KDKKEIVLQINGKIKDKILLNKETGEKELKEIAME  811
             +  EIV+QI+GK+K K+++ K+ +  EL+E+A+ 
Sbjct  770  ENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALA  804

478) leuS in NC_010803


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  719 bits (2721),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 441/843 (53%), Positives = 602/843 (72%), Gaps = 53/843 (6%)

Query  3    YEFSAIEKKWQAIWQENGTFKTGESTEKPKYYVLDMFPYPSGSGLHVGHLEGYTASDIIA  62
            Y+ +AIE KWQA+W +N TFKTG  + KPK+Y LDMFPYPSG+GLHVGH EGYTA+DI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RFKRSRGFNVLHPMGWDAFGLPAEQYAIKTGTHPKITTENNIRSFRETLQAMGFSYDWSK  122
            RFKR++G NVLHPMGWDAFGLPAEQYA+ TG +P   T +NI +F+  ++A+GFSYDW +
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EINTTDPAYFKWTQWIFLRLYEMGLAYMSDVDVNWCEELKTVLANEEV---DEKIADGYT  179
            E+NTTDP Y+KWTQWIF +LYE GLAY ++V VNW EEL T +ANEEV   +    +GY 
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  180  VVRKPLRQWVLKITAYaerlladldeleWPENVKQMQRNWIGRSEGVEIDFELRCHGKNL  239
            VVRKP+RQW+LKITAYAERLL DL+E++WPE++K+MQRNWIG+S G ++ F ++  +K++
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  240  RVYTTRPDTLFGATYLVVSPEHPLAEKLATADNLKEVKAYISRAKLKTELERTGLQKDKT  299
             V+TTRPDTLFGATY V++PEH+L + ++T+D+   V  Y  +A LK++L RT+L K+KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  300  GVFTGSYAINPATGNPLPVWISDFVLISYGTGAIMSVPAHDSRDWEFAKKFDLPIIEVIK  359
            GV TGSYAINP  G+ +PVWI+D+VL SYGTGAIM+VPAHD RDWEFAK+F+L II V+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  360  SPHDVNDAVFEGKESVPVNSSNSEITIDGLPFREAFDTMASWLEKKGAGKRTINYKLRDW  419
            + + V++A F   +++ +NS      +DGL    A+  M  WLE  G G+  + Y+LRDW
Sbjct  364  GGN-VEEAAF-TEDGLHINSD----FLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDW  417

Query  420  IFSRQRYWGEPIPIKHYEDGTLRT--ETILPLTLPDVEAYQPSETGESPLATIHDWL-YG  476
            +FSRQRYWGEPIPI H EDGT  +  E+ LPL LP     +PS TGESPLA + DWL   
Sbjct  418  LFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT  477

Query  477  SDEFGSFRRETNTMPQWAGSCWYYLRFIDPENSGRLIDPEREKYWMNVDLYIGGAEHAVL  536
             ++    RRETNTMPQWAGS WYYLR+IDP+N+ +L D E  K W+ VD+Y+GGAEHAVL
Sbjct  478  REDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVL  537

Query  537  HLLYARFWHKVLFDLNVVSTVEPFRKLFNQGMILG-------------------------  571
            HLLYARFWHKVL+DL VV+T EPF+KLFNQGMILG                         
Sbjct  538  HLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFH  597

Query  572  --------EDNEKMSKSRGNVIPADHVLKTYGADAVRLYEMFLGPLEQVKPWNTNGIEGI  623
                    +   KMSKS  NV+ +D+V+  YGAD++R+YEMF+GPL+   +W+ +G+EG 
Sbjct  598  VETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGS  657

Query  624  SRFLGKVWRLVYPEQEGNKAELTDETMPEELLRRLHKTIRKVTEDTEALKFNTAIAEMMV  683
             +FL++V RL+         E+T+E  +  L +  + T++ VTE+ + +KFNTAIA++MV
Sbjct  658  RKFLDRVYRLI------TTKEITEEN-SGALDKVYNETVKAVTEQVDQMKFNTAIAQLMV  710

Query  684  LVNELQRNGCRNRTAVESMILLLAPYAPHIAEELWQA-TGHTGSISNEPFPNYVAGLATD  742
            +VN  ++++        + + L+AP+APH++EELWQA T+   SIS  P P+Y  +   +
Sbjct  711  FVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVE  770

Query  743  SVVQIAVQVNGKLRGTFSTPAGTPQNSLIETARNVESVMKFLEGKAIMREIVVPDKLVNF  802
            + V+I VQ++GK+++ +  + + +++ L E A   E V   + GK I++ I VP+KLVN+
Sbjct  771  NDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNI  830

Query  803  AVK  805
             +K
Sbjct  831  VIK  833

479) leuS in NC_001318


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  719 bits (2721),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 417/815 (52%), Positives = 598/815 (74%), Gaps = 15/815 (1%)

Query  1    MSKYEFIKIEKKWQEFWDNNKTYKVEEDPSIPKEKRLYILDMFPYPSANGLHVGHPEGYT  60
            M+ Y+   IE KWQ FW +N T+K   D+S PK   +Y LDMFPYPS+ GLHVGHPEGYT
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPK---FYALDMFPYPSGAGLHVGHPEGYT  57

Query  61   ATDIFGRYKLLNGFHVLHPIGFDSFGLPAENYAIQTGTHPQKSTEENINKFKKQIKALGF  120
            ATDI++R+K  +G +VLHP+G D+FGLPAE+YA++TG +P   T ENI +FK+QI+ALGF
Sbjct  58   ATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGF  117

Query  121  AYDWDREIRTHEENYYKWTQWIFLQLYKKGLAYVKEMPVWYCPELGTVLANEEIIQTSDG  180
            +YDWDRE+ T + NYYKWTQWIF +LY KGLAY  E+PV    ELGT +ANEE++  +  
Sbjct  118  SYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDG--  175

Query  181  PKSERGSYSVEKKYLRQWVLKITKYAerllddleeleWPESVKEMQRNWIGKSTGVEIEF  240
              SERG+Y+V +K +RQW+LKIT YAERLL+DLEE++WPES+K+MQRNWIGKSTG ++ F
Sbjct  176  -TSERGGYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTF  234

Query  241  EIEGHSDKIKVFTTRPDTIFGITYLVIAPENKLIEKITKNNFKQNVLKYVKHEELKSDLN  300
             + +    + VFTTRPDT+FG TY V+APE+ L++ IT ++  + V  Y ++  LKSDL 
Sbjct  235  KVKDTDKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLA  294

Query  301  RTSLEKDKSGVFTGSYAFHPITNEKIPIWVGSYVLGTYGTGAVMGVPAHDERDFQFAKKY  360
            RT L K+K+GV TGSYA++P+    +P+W++ YVL++YGTGA+M+VPAHDERD +FAK++
Sbjct  295  RTDLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQF  354

Query  361  QLKILPVISKSGKNEILEKAFVDDGISINSPNEF-NNLKNSEVKDKVIKWLTKNKKGKEK  419
            +L I+PV+  +   ++ E AF +DG+ INS  +F + L ++    K++ WL  +  G+E+
Sbjct  355  NLDIIPVLEGG---NVEEAAFTEDGLHINS--DFLDGLDKASAIAKMVEWLEAEGVGNEN  409

Query  420  VAYKLRDWIFSRQRYWGEPIPILFDKLGNAIPLEENDLPLKLPEIANYKPSGTGESPLSR  479
            V+Y+LRDW+FSRQRYWGEPIPI+    G + ++ E++LPL LP   + +PSGTGESPL+ 
Sbjct  410  VTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLAN  469

Query  480  IKDWVNV-KDMGFT--RETNTMPQWAGSCWYYLRYLDPKNSKEFANKKKIEYWMPVDLYI  536
            + DW++V ++ G    RETNTMPQWAGS WYYLRY+DP N+  +A+   +  W+PVD+Y+
Sbjct  470  VTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYV  529

Query  537  GGAEHTVLHLLYSRFWHKVLYDLGYVNTKEPFKKLINQGIITSFSYQKENGVLIPNDQVI  596
            GGAEH+VLHLLY+RFWHKVLYDLG V TKEPF+KL+NQG+I + SY+   G L++ D+V 
Sbjct  530  GGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVE  589

Query  597  EkdnkffdkkdnkEVTQVIAKMSKSLKNVINPDDIIKEFGADSMRIYEMFMGPLTDSKPW  656
             +D  FF+     E+ Q  AKMSKSLKNV+NPDD++ ++GAD++R+YEMFMGPL  S +W
Sbjct  590  KRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAW  649

Query  657  NTKGIIGVFRFLNKIWNLREKELSKENPPREIISELHKVIKKVTEDTEKLNFNTAISAMM  716
            +  G+ G  +FL+++  L       E+ +  +    +  +K VTE+ ++++FNTAI+ +M
Sbjct  650  SEEGLEGSRKFLDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLM  709

Query  717  IFINELLKYEKNYLNIFKPFIIILSPYAPHLAEELWEYIGELPSLFKNSKWPKFDESLII  776
            +F+N   K +K + +  K F+ +++P+APHL+EELW+ +      +    WP +DES ++
Sbjct  710  VFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLV  769

Query  777  KGKKEIVLQINGKIKDKILLNKETGEKELKEIAME  811
                EIV+QI+GK+K K+++ K+ +  EL+E+A+ 
Sbjct  770  ENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALA  804

480) leuS in NC_015946


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  718 bits (2716),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 446/841 (54%), Positives = 604/841 (72%), Gaps = 50/841 (5%)

Query  3    FSHKAIEKKWQKFWKENDLYKT-TDTSDKKSYVLDMFPYPSGAGLHVGHIKGYTATDVFA  61
            + H AIE KWQ FW +N+ +KT TD+S  K Y LDMFPYPSGAGLHVGH  GYTATD+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  62   RFKRMQGYDVLHPIGWDAFGLPAEQYALKTGNDPREFTLKNIDNFRVQLQKMGFSYDFDK  121
            RFKR QG +VLHP+GWDAFGLPAEQYA+ TGNDP EFT  NI NF+ Q++ +GFSYD D+
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  122  EVNTADANYYKITQQIFKKLYQHNLAEKRDVEVNWCQELGTVLANDEIIEKNGMMLSERG  181
            EVNT+D+NYYK TQ IF KLY+  LA   +V VNW +ELGT +AN+E++       SERG
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGT---SERG  180

Query  182  EHPVTKKKMRQWVLKITDYAEKLLQGLDELDWPQSIKDLQKNWIGKSVGAEIIFKSNDI-  240
              PV +K MRQW+LKIT YAE+LL++L+E+DWP+SIKD+Q+NWIGKS GA++ FK +D  
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  241  -EIPVFTTRADTIYGVSYIVLAPENELVLKLTTADKLAEVKNYIQQTSSKSEIDRKDESR  299
             ++ VFTTR+DT++G +Y VLAPE+ LV  +TT+D+   V +Y +Q+S KS++ R D ++
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  300  PKTGVFIGSYATNPVTKQAVEIWISDYVLSDYGTGAVMAVPAHDKRDWEFATKFNLPIKF  359
             KTGV  GSYA NPV  + + +WI+DYVL+ YGTGA+MAVPAHD RDWEFA +FNL I  
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  360  VIKTKD-QSKAFVGEDIHINSDILDGLDRVQALEVIYKYLEDNHLGIRKINYKLRDWLFS  418
            V+   + +  AF  +++HINSD+LDGLD+  A+  +   LE + +G  ++ Y+LRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  419  RQRFYGEPFPVLYTKDQKIILVDDKYLPVTLPETEYIKPTKTGESPLANLTDWVNFEIA-  477
            RQR+ GEP+P++   D     V +  LP+ LP T  I+P+ TGESPLAN+TDW++     
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  478  GVKYKRETNTMPQSAGSSWYFIAYLLTDAPNKLIDLDSEQAKQRMQKWLPVDLYIGGQEH  537
            GVK +RETNTMPQ AGSSWY++ Y+  +  +KL D       + +++WLPVD+Y+GG EH
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLAD------EELLKQWLPVDIYVGGAEH  534

Query  538  AVGHLLYARFWTHFLYDLGICPVKEPFKNLFNQGMILGP---DGR---------------  579
            AV HLLYARFW   LYDLG+ P KEPF++LFNQGMILG    D+R               
Sbjct  535  AVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGS  594

Query  580  ---------------KMSKSWGNVINPDDVIDSHGADALRLYEMFMGPLDASLPWSFDGL  624
                           KMSKS  NV+NPDDV++  GAD+LR+YEMFMGPLDAS++WS +GL
Sbjct  595  FFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGL  654

Query  625  DASLKWLNRCYRMINKISFSNQNNANLDFVYNDVVKKVTEMVSDLKFNTAISQLMVLVNA  684
            ++S K L+R YR+I    ++++N++ LD VYN+ VK VTE V ++KFNTAI+QLMV+VNA
Sbjct  655  EGSRKFLDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNA  714

Query  685  IYKEKEGTVYKAYVEGFVKMLSLFAPHLAEELWEKL-GYNSSVTKQSWPSYDKSKLVRNT  743
               +KE+ ++  Y  GFV++++ FAPHL+EELW+ L +   S++  +WPSYD SKLV N 
Sbjct  715  A--NKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVEND  772

Query  744  VVVAFQVNGKLRSTIEVEKGTNKETLIKLAKNDEHVLRFIKGCQIIKEIAIVDKIVNIVV  803
            V +  Q++GK+++ + V K+ ++E L  +A  +E V   I G +IIK IA+ +K+VNIV+
Sbjct  773  VEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

Query  804  K  804
            K
Sbjct  833  K  833

481) leuS in NC_021083


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  717 bits (2711),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 447/841 (54%), Positives = 604/841 (72%), Gaps = 50/841 (5%)

Query  3    FSHKAIEKKWQKFWKENDLYKT-TDTSDKKSYVLDMFPYPSGAGLHVGHIKGYTATDVFA  61
            + H AIE KWQ FW +N+ +KT TD+S  K Y LDMFPYPSGAGLHVGH  GYTATD+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  62   RFKRMQGYDVLHPIGWDAFGLPAEQYALKTGNDPREFTLKNIDNFRVQLQKMGFSYDFDK  121
            RFKR QG +VLHP+GWDAFGLPAEQYA+ TGNDP EFT  NI NF+ Q++ +GFSYD D+
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  122  EVNTADANYYKITQQIFKKLYQHNLAEKRDVEVNWCQELGTVLANDEIIEKNGIMLSERG  181
            EVNT+D+NYYK TQ IF KLY+  LA   +V VNW +ELGT +AN+E++       SERG
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGT---SERG  180

Query  182  EHPVAKKKMRQWVLKITDYAEKLLQGLDELDWPQSIKDLQKNWIGKSVGAEIIFKSNDI-  240
              PV +K MRQW+LKIT YAE+LL++L+E+DWP+SIKD+Q+NWIGKS GA++ FK +D  
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  241  -EIPVFTTRADTIYGVSYIVLAPENELVLKLTTADKLAEVKNYIQQTSSKSEIDRKDESR  299
             ++ VFTTR+DT++G +Y VLAPE+ LV  +TT+D+   V +Y +Q+S KS++ R D ++
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  300  PKTGVFIGSYATNPVTKQAVEIWISDYVLSDYGTGAVMAVPAHDKRDWEFATKFNLPIKF  359
             KTGV  GSYA NPV  + + +WI+DYVL+ YGTGA+MAVPAHD RDWEFA +FNL I  
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  360  VIKTKD-QSKAFVGEDIHINSDILDGLDRVQALEVIYKYLEDNHLGIRKINYKLRDWLFS  418
            V+   + +  AF  +++HINSD+LDGLD+  A+  +   LE + +G  ++ Y+LRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  419  RQRFYGEPFPVLYTKDQKIILVDDKYLPVTLPETEYIKPTKTGESPLANLTDWVNFEIA-  477
            RQR+ GEP+P++   D     V +  LP+ LP T  I+P+ TGESPLAN+TDW++     
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  478  GVKYKRETNTMPQSAGSSWYFIAYLLTDAPNKLIDLDSEQAKQRMQKWLPVDLYIGGQEH  537
            GVK +RETNTMPQ AGSSWY++ Y+  +  +KL D       + +++WLPVD+Y+GG EH
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLAD------EELLKQWLPVDIYVGGAEH  534

Query  538  AVGHLLYARFWTHFLYDLGICPVKEPFKNLFNQGMILGP---DGR---------------  579
            AV HLLYARFW   LYDLG+ P KEPF++LFNQGMILG    D+R               
Sbjct  535  AVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGS  594

Query  580  ---------------KMSKSWGNVINPDDVIDSHGADALRLYEMFMGPLDASLPWSFDGL  624
                           KMSKS  NV+NPDDV++  GAD+LR+YEMFMGPLDAS++WS +GL
Sbjct  595  FFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGL  654

Query  625  DASLKWLNRCYRMINKISFSNQNNANLDFVYNDVVKKVTEMVSDLKFNTAISQLMVLVNA  684
            ++S K L+R YR+I    ++++N++ LD VYN+ VK VTE V ++KFNTAI+QLMV+VNA
Sbjct  655  EGSRKFLDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNA  714

Query  685  IYKEKEGTVYKAYVEGFVKMLSLFAPHLAEELWEKL-GYNSSVTKQSWPSYDKSKLVRNT  743
               +KE+ ++  Y  GFV++++ FAPHL+EELW+ L +   S++  +WPSYD SKLV N 
Sbjct  715  A--NKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVEND  772

Query  744  VVVAFQVNGKLRSTIEVEKGTNKETLIKLAKNDEHVLRFIKGYQIIKEIAVVDKIVNIVV  803
            V +  Q++GK+++ + V K+ ++E L  +A  +E V   I G +IIK IAV +K+VNIV+
Sbjct  773  VEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

Query  804  K  804
            K
Sbjct  833  K  833

482) leuS in NC_009337


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  717 bits (2711),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 439/843 (53%), Positives = 595/843 (71%), Gaps = 53/843 (6%)

Query  3    YDFSKTEKKWQARWKQQETFKTGEAPEKPKYYVLDMFPYPSGSGLHVGHLEGYTASDISA  62
            YD +  E KWQA W +++TFKTG  + KPK+Y LDMFPYPSG+GLHVGH EGYTA+DI +
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYRRSRGYNVLHPMGWDAFGLPAEQFAIKTGTHPSDTTQKNIANFKETLQAMGFSYDWSR  122
            R++R++G NVLHPMGWDAFGLPAEQ+A+ TG +P++ T  NIANFK  ++A+GFSYDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EINTTDPGYFQWTQWIFLKLHEMGLAYMSEVDVNWCVELRAVLANEEV---EEKLADGLT  179
            E+NTTDP Y++WTQWIF KL E GLAY +EV VNW  EL + +ANEEV        +G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  180  VVRRPLRQWVLKITAYADRLLEDLDGLDWPENVKQMQRNWIGRSEGVEVDFELRCHRTML  239
            VVR+P+RQW+LKITAYA+RLLEDL+ +DWPE++K+MQRNWIG+S G +V F ++     +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  240  RVYTTRPDTLFGATYLVISPEHAMAEKLATAQQLVAVKEYIAKAKLKTELERTGLQKDKT  299
             V+TTRPDTLFGATY V++PEHA+ + ++T++Q  AV +Y  +A LK++L RT+L K+KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  300  GVFTGSYAINPATGEPLPVWISDFVLTSYGTGAIMSVPAHDSRDWEFAKQYGLPIIEVVK  359
            GV TGSYAINP  G  +PVWI+D+VL+SYGTGAIM+VPAHD RDWEFAKQ+ L II V+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  360  SPHDVQQEVFEGKDSTVVNSSNNDISLNGLAFPEAFELMASWLEKKKAGKRKVNYRLRDW  419
            + + V++  F   +  +    N+D+ L+GL  + A+  M  WLE    G+ +V YRLRDW
Sbjct  364  GGN-VEEAAFTEDGLHI----NSDF-LDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDW  417

Query  420  IFSRQRYWGEPIPIKHYPDGTLK--PETSLPLMLPEVEAYQPTETGESPLANIPEWLNGT  477
            +FSRQRYWGEPIPI H  DGT    PE+ LPL+LP     +P+ TGESPLAN+ +WL+ T
Sbjct  418  LFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT  477

Query  478  DENG-PFRRETNTMPQWAGSCWYYLRFIDPHNSKLPVDPAKEAYWMNVDLYIGGAEHAVL  536
             E+G   RRETNTMPQWAGS WYYLR+IDPHN+    D      W+ VD+Y+GGAEHAVL
Sbjct  478  REDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVL  537

Query  537  HLLYARFWHKVLFDLKVVSTKEPFQRLFNQGMILG-------------------------  571
            HLLYARFWHKVL+DL VV+TKEPFQ+LFNQGMILG                         
Sbjct  538  HLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFH  597

Query  572  --------EDNEKMSKSRGNVIPADHVLQTYGADAVRLYEMFLGPLEQVKPWNTNGIEGI  623
                    +   KMSKS  NV+ +D+V++ YGAD++R+YEMF+GPL+   +W+ +G+EG 
Sbjct  598  VETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGS  657

Query  624  SRFLSRVWRLVWPEPEGTRADLSTLAPSPDLLRRMHKTIKKVAADTENLKFNTAIAEMMV  683
             +FL RV RL+      T  +++    S  L +  + T+K V+ + +++KFNTAIA++MV
Sbjct  658  RKFLDRVYRLI------TTKEITE-ENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMV  710

Query  684  FTNELHRTGEGSRIAVETlllllAPYAPHLSEELWEAL-GHQESISLAPFPEFDPELAQD  742
            F N  ++ +         ++ L+AP+APHL+EELW+AL +  ESIS  P P +D     +
Sbjct  711  FVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVE  770

Query  743  KEVTIAVQVNGKLRGSFTAAPGSPKEQLLNEAKALEGVKKFLEGVTIMKEIVVPDKLINF  802
            ++V I VQ++GK+++ +  A + ++E+L + A A E V+  + G  I+K I VP+KL+N+
Sbjct  771  NDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNI  830

Query  803  AVK  805
             +K
Sbjct  831  VIK  833

483) leuS in NC_021179


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  716 bits (2708),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 440/878 (51%), Positives = 610/878 (70%), Gaps = 51/878 (5%)

Query  3    YPFRALEKKWQAYWRDKRVFCVSEDERFPPERRAYVLDMFPYPSAQGLHVGHPEGYTATD  62
            Y   A+E KWQA+W D++ F  + D   ++  + Y LDMFPYPS+ GLHVGHPEGYTATD
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTD---ASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  63   IYCRYLRMGGYNVLHPMGFDAFGLPAENFALKTGTHPRVSTSANCDTFRRQIQSFGFSYD  122
            I  R+ R  G NVLHPMG DAFGLPAE++A+ TG +P   T+ N   F+RQI+++GFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  123  WEREISTADPEYYRWTQWLFLKLYEKGLAYEATAPINWCPSCKTGLANEEV-RDACCERC  181
            W+RE++T+DP+YY+WTQW+F KLYEKGLAYEA  P+NW     T++ANEEV  D+  ER 
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  182  GAEVTRRGVRQWMVRITAYAERLLSDLDELDWPESVKQMQRNWIGKSCGAEIDFPVDAPA  241
            G  V R+ +RQWM++ITAYAERLL DL+E+DWPES+K+MQRNWIGKS GA++ F V    
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  242  CSVHDKLPQTIRVYTTRADTLFGVTYLVLAPEHEAVTALTTHaqraavqayvqraaKKND  301
                    + + V+TTR+DTLFG TY VLAPEH  V A+TT  Q  AV  Y ++A+ K+D
Sbjct  241  --------KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSD  292

Query  302  LERTDLAKEKTGVFTGAYVRNPINDMRIPVWVGDYVLVSYGTGAVMAVPAHDQRDWDFAT  361
            L RTDLAKEKTGV TG+Y  NP+N+  +PVW++DYVL SYGTGA+MAVPAHD+RDW+FA 
Sbjct  293  LARTDLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAK  352

Query  362  RFGLPKLTVVSADYTATVPNSNSPQGTVLQRCVSDEGFVVNSGAFNGLASADARERIVAH  421
            +F L  + V+ +             G V +   +++G+ +NS+ ++GL  A A  ++V  
Sbjct  353  QFNLDIIPVLEG-------------GNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEW  399

Query  422  LEMRGAGARRVTYRLRDWVFSRQRYWGEPIPLVHCPSCGVVplpesalplllpeTADFTP  481
            LE  G G   VTYRLRDW+FSRQRYWGEPIP++H       ++PES LPL+LP T D+ P
Sbjct  400  LEAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRP  459

Query  482  TEDGQGPLARACTWLRVPCPQCASDAVRETNTMPQWAGSCWYYLRYMDPRNKTAFCAPEK  541
            +  G++PLA    WL V   + +  + RETNTMPQWAGS WYYLRY+DP+N   +   E 
Sbjct  460  SGTGESPLANVTDWLEV-TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEEL  518

Query  542  ERYWAPVALYVGGAEHAVLHLLYARFWHKVLYDLGLVSTKEPFARLVNQGMITSYAYRRK  601
             + W PV +YVGGAEHAVLHLLYARFWHKVLYDLG+V+TKEPF +L NQGMI + +YR  
Sbjct  519  LKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDS  578

Query  602  NGALVPHDEVHTNAQGTYVHARTGEKLECVVAKMSKALKNVVNPDDMIAAYGADACRVYE  661
             GALV+ D V+   +G++ H  TGE LE   AKMSK+LKNVVNPDD++  YGAD+ RVYE
Sbjct  579  RGALVATDKVEKR-DGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYE  637

Query  662  MFMGPLEASKPWNTQGLVGVFRFLEKIWVLAGRVAAANGIPQDSRAEPPGDLHAQKKSCS  721
            MFMGPL+AS +W+ +GL G  +FL+++     R+ +++ I +++ +              
Sbjct  638  MFMGPLDASIAWSEEGLEGSRKFLDRVY----RLITTKEITEENSG--------------  679

Query  722  MYALETLLHRTIQKVTDDTSALSFNTAISQMMIFVNEATRVARRMPLPSKMWEMFVKILS  781
              AL+ + + T++ VT++   + FNTAI+Q+M+FVN A +  +  +  +K    FV++++
Sbjct  680  --ALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAK---GFVQLIA  734

Query  782  PYAPHLAEELWE-MCGHTHTIAYEPWPQVDPARVAPHVCSVVVQVNGKVRDTFSVAPNAP  840
            P+APHL+EELW+ + +  ++I+Y PWP  D +++  +   +VVQ++GKV+  + VA + +
Sbjct  735  PFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLS  794

Query  841  NEELEQKARETAGARKFLGTQQPKRVVIVPNKLVNFVL  878
             EEL++ A      +  ++ ++  +V+ VPNKLVN+V+
Sbjct  795  REELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

484) leuS in NC_016848


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  716 bits (2708),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 440/878 (51%), Positives = 610/878 (70%), Gaps = 51/878 (5%)

Query  3    YPFRALEKKWQAYWRDKRVFCVSEDERFPPERRAYVLDMFPYPSAQGLHVGHPEGYTATD  62
            Y   A+E KWQA+W D++ F  + D   ++  + Y LDMFPYPS+ GLHVGHPEGYTATD
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTD---ASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  63   IYCRYLRMGGYNVLHPMGFDAFGLPAENFALKTGTHPRVSTSANCDTFRRQIQSFGFSYD  122
            I  R+ R  G NVLHPMG DAFGLPAE++A+ TG +P   T+ N   F+RQI+++GFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  123  WEREISTADPEYYRWTQWLFLKLYEKGLAYEATAPINWCPSCKTGLANEEV-RDACCERC  181
            W+RE++T+DP+YY+WTQW+F KLYEKGLAYEA  P+NW     T++ANEEV  D+  ER 
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  182  GAEVTRRGVRQWMVRITAYAERLLSDLDELDWPESVKQMQRNWIGKSCGAEIDFPVDAPA  241
            G  V R+ +RQWM++ITAYAERLL DL+E+DWPES+K+MQRNWIGKS GA++ F V    
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  242  CSVHDKLPQTIRVYTTRADTLFGVTYLVLAPEHEAVTALTTHaqraavqayvqraaKKND  301
                    + + V+TTR+DTLFG TY VLAPEH  V A+TT  Q  AV  Y ++A+ K+D
Sbjct  241  --------KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSD  292

Query  302  LERTDLAKEKTGVFTGAYVRNPINDMRIPVWVGDYVLVSYGTGAVMAVPAHDQRDWDFAT  361
            L RTDLAKEKTGV TG+Y  NP+N+  +PVW++DYVL SYGTGA+MAVPAHD+RDW+FA 
Sbjct  293  LARTDLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAK  352

Query  362  RFGLPKLTVVSADYTATVPNSNSPQGTVLQRCVSDEGFVVNSGAFNGLASADARERIVAH  421
            +F L  + V+ +             G V +   +++G+ +NS+ ++GL  A A  ++V  
Sbjct  353  QFNLDIIPVLEG-------------GNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEW  399

Query  422  LEMRGAGARRVTYRLRDWVFSRQRYWGEPIPLVHCPSCGVVplpesalplllpeTADFTP  481
            LE  G G   VTYRLRDW+FSRQRYWGEPIP++H       ++PES LPL+LP T D+ P
Sbjct  400  LEAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRP  459

Query  482  TEDGQGPLARACTWLRVPCPQCASDAVRETNTMPQWAGSCWYYLRYMDPRNKTAFCAPEK  541
            +  G++PLA    WL V   + +  + RETNTMPQWAGS WYYLRY+DP+N   +   E 
Sbjct  460  SGTGESPLANVTDWLEV-TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEEL  518

Query  542  ERYWAPVALYVGGAEHAVLHLLYARFWHKVLYDLGLVSTKEPFARLVNQGMITSYAYRRK  601
             + W PV +YVGGAEHAVLHLLYARFWHKVLYDLG+V+TKEPF +L NQGMI + +YR  
Sbjct  519  LKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDS  578

Query  602  NGALVPHDEVHTNAQGTYVHARTGEKLECVVAKMSKALKNVVNPDDMIAAYGADACRVYE  661
             GALV+ D V+   +G++ H  TGE LE   AKMSK+LKNVVNPDD++  YGAD+ RVYE
Sbjct  579  RGALVATDKVEKR-DGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYE  637

Query  662  MFMGPLEASKPWNTQGLVGVFRFLEKIWVLAGRVAAANGIPQDSRAEPPGDLHAQKKSCS  721
            MFMGPL+AS +W+ +GL G  +FL+++     R+ +++ I +++ +              
Sbjct  638  MFMGPLDASIAWSEEGLEGSRKFLDRVY----RLITTKEITEENSG--------------  679

Query  722  MYALETLLHRTIQKVTDDTSALSFNTAISQMMIFVNEATRVARRMPLPSKMWEMFVKILS  781
              AL+ + + T++ VT++   + FNTAI+Q+M+FVN A +  +  +  +K    FV++++
Sbjct  680  --ALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAK---GFVQLIA  734

Query  782  PYAPHLAEELWE-MCGHTHTIAYEPWPQVDPARVAPHVCSVVVQVNGKVRDTFSVAPNAP  840
            P+APHL+EELW+ + +  ++I+Y PWP  D +++  +   +VVQ++GKV+  + VA + +
Sbjct  735  PFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLS  794

Query  841  NEELEQKARETAGARKFLGTQQPKRVVIVPNKLVNFVL  878
             EEL++ A      +  ++ ++  +V+ VPNKLVN+V+
Sbjct  795  REELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

485) leuS in NC_016843


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  716 bits (2708),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 440/878 (51%), Positives = 610/878 (70%), Gaps = 51/878 (5%)

Query  3    YPFRALEKKWQAYWRDKRVFCVSEDERFPPERRAYVLDMFPYPSAQGLHVGHPEGYTATD  62
            Y   A+E KWQA+W D++ F  + D   ++  + Y LDMFPYPS+ GLHVGHPEGYTATD
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTD---ASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  63   IYCRYLRMGGYNVLHPMGFDAFGLPAENFALKTGTHPRVSTSANCDTFRRQIQSFGFSYD  122
            I  R+ R  G NVLHPMG DAFGLPAE++A+ TG +P   T+ N   F+RQI+++GFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  123  WEREISTADPEYYRWTQWLFLKLYEKGLAYEATAPINWCPSCKTGLANEEV-RDACCERC  181
            W+RE++T+DP+YY+WTQW+F KLYEKGLAYEA  P+NW     T++ANEEV  D+  ER 
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  182  GAEVTRRGVRQWMVRITAYAERLLSDLDELDWPESVKQMQRNWIGKSCGAEIDFPVDAPA  241
            G  V R+ +RQWM++ITAYAERLL DL+E+DWPES+K+MQRNWIGKS GA++ F V    
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  242  CSVHDKLPQTIRVYTTRADTLFGVTYLVLAPEHEAVTALTTHaqraavqayvqraaKKND  301
                    + + V+TTR+DTLFG TY VLAPEH  V A+TT  Q  AV  Y ++A+ K+D
Sbjct  241  --------KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSD  292

Query  302  LERTDLAKEKTGVFTGAYVRNPINDMRIPVWVGDYVLVSYGTGAVMAVPAHDQRDWDFAT  361
            L RTDLAKEKTGV TG+Y  NP+N+  +PVW++DYVL SYGTGA+MAVPAHD+RDW+FA 
Sbjct  293  LARTDLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAK  352

Query  362  RFGLPKLTVVSADYTATVPNSNSPQGTVLQRCVSDEGFVVNSGAFNGLASADARERIVAH  421
            +F L  + V+ +             G V +   +++G+ +NS+ ++GL  A A  ++V  
Sbjct  353  QFNLDIIPVLEG-------------GNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEW  399

Query  422  LEMRGAGARRVTYRLRDWVFSRQRYWGEPIPLVHCPSCGVVplpesalplllpeTADFTP  481
            LE  G G   VTYRLRDW+FSRQRYWGEPIP++H       ++PES LPL+LP T D+ P
Sbjct  400  LEAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRP  459

Query  482  TEDGQGPLARACTWLRVPCPQCASDAVRETNTMPQWAGSCWYYLRYMDPRNKTAFCAPEK  541
            +  G++PLA    WL V   + +  + RETNTMPQWAGS WYYLRY+DP+N   +   E 
Sbjct  460  SGTGESPLANVTDWLEV-TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEEL  518

Query  542  ERYWAPVALYVGGAEHAVLHLLYARFWHKVLYDLGLVSTKEPFARLVNQGMITSYAYRRK  601
             + W PV +YVGGAEHAVLHLLYARFWHKVLYDLG+V+TKEPF +L NQGMI + +YR  
Sbjct  519  LKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDS  578

Query  602  NGALVPHDEVHTNAQGTYVHARTGEKLECVVAKMSKALKNVVNPDDMIAAYGADACRVYE  661
             GALV+ D V+   +G++ H  TGE LE   AKMSK+LKNVVNPDD++  YGAD+ RVYE
Sbjct  579  RGALVATDKVEKR-DGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYE  637

Query  662  MFMGPLEASKPWNTQGLVGVFRFLEKIWVLAGRVAAANGIPQDSRAEPPGDLHAQKKSCS  721
            MFMGPL+AS +W+ +GL G  +FL+++     R+ +++ I +++ +              
Sbjct  638  MFMGPLDASIAWSEEGLEGSRKFLDRVY----RLITTKEITEENSG--------------  679

Query  722  MYALETLLHRTIQKVTDDTSALSFNTAISQMMIFVNEATRVARRMPLPSKMWEMFVKILS  781
              AL+ + + T++ VT++   + FNTAI+Q+M+FVN A +  +  +  +K    FV++++
Sbjct  680  --ALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAK---GFVQLIA  734

Query  782  PYAPHLAEELWE-MCGHTHTIAYEPWPQVDPARVAPHVCSVVVQVNGKVRDTFSVAPNAP  840
            P+APHL+EELW+ + +  ++I+Y PWP  D +++  +   +VVQ++GKV+  + VA + +
Sbjct  735  PFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLS  794

Query  841  NEELEQKARETAGARKFLGTQQPKRVVIVPNKLVNFVL  878
             EEL++ A      +  ++ ++  +V+ VPNKLVN+V+
Sbjct  795  REELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

486) leuS in NC_016842


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  716 bits (2708),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 440/878 (51%), Positives = 610/878 (70%), Gaps = 51/878 (5%)

Query  3    YPFRALEKKWQAYWRDKRVFCVSEDERFPPERRAYVLDMFPYPSAQGLHVGHPEGYTATD  62
            Y   A+E KWQA+W D++ F  + D   ++  + Y LDMFPYPS+ GLHVGHPEGYTATD
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTD---ASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  63   IYCRYLRMGGYNVLHPMGFDAFGLPAENFALKTGTHPRVSTSANCDTFRRQIQSFGFSYD  122
            I  R+ R  G NVLHPMG DAFGLPAE++A+ TG +P   T+ N   F+RQI+++GFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  123  WEREISTADPEYYRWTQWLFLKLYEKGLAYEATAPINWCPSCKTGLANEEV-RDACCERC  181
            W+RE++T+DP+YY+WTQW+F KLYEKGLAYEA  P+NW     T++ANEEV  D+  ER 
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  182  GAEVTRRGVRQWMVRITAYAERLLSDLDELDWPESVKQMQRNWIGKSCGAEIDFPVDAPA  241
            G  V R+ +RQWM++ITAYAERLL DL+E+DWPES+K+MQRNWIGKS GA++ F V    
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  242  CSVHDKLPQTIRVYTTRADTLFGVTYLVLAPEHEAVTALTTHaqraavqayvqraaKKND  301
                    + + V+TTR+DTLFG TY VLAPEH  V A+TT  Q  AV  Y ++A+ K+D
Sbjct  241  --------KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSD  292

Query  302  LERTDLAKEKTGVFTGAYVRNPINDMRIPVWVGDYVLVSYGTGAVMAVPAHDQRDWDFAT  361
            L RTDLAKEKTGV TG+Y  NP+N+  +PVW++DYVL SYGTGA+MAVPAHD+RDW+FA 
Sbjct  293  LARTDLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAK  352

Query  362  RFGLPKLTVVSADYTATVPNSNSPQGTVLQRCVSDEGFVVNSGAFNGLASADARERIVAH  421
            +F L  + V+ +             G V +   +++G+ +NS+ ++GL  A A  ++V  
Sbjct  353  QFNLDIIPVLEG-------------GNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEW  399

Query  422  LEMRGAGARRVTYRLRDWVFSRQRYWGEPIPLVHCPSCGVVplpesalplllpeTADFTP  481
            LE  G G   VTYRLRDW+FSRQRYWGEPIP++H       ++PES LPL+LP T D+ P
Sbjct  400  LEAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRP  459

Query  482  TEDGQGPLARACTWLRVPCPQCASDAVRETNTMPQWAGSCWYYLRYMDPRNKTAFCAPEK  541
            +  G++PLA    WL V   + +  + RETNTMPQWAGS WYYLRY+DP+N   +   E 
Sbjct  460  SGTGESPLANVTDWLEV-TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEEL  518

Query  542  ERYWAPVALYVGGAEHAVLHLLYARFWHKVLYDLGLVSTKEPFARLVNQGMITSYAYRRK  601
             + W PV +YVGGAEHAVLHLLYARFWHKVLYDLG+V+TKEPF +L NQGMI + +YR  
Sbjct  519  LKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDS  578

Query  602  NGALVPHDEVHTNAQGTYVHARTGEKLECVVAKMSKALKNVVNPDDMIAAYGADACRVYE  661
             GALV+ D V+   +G++ H  TGE LE   AKMSK+LKNVVNPDD++  YGAD+ RVYE
Sbjct  579  RGALVATDKVEKR-DGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYE  637

Query  662  MFMGPLEASKPWNTQGLVGVFRFLEKIWVLAGRVAAANGIPQDSRAEPPGDLHAQKKSCS  721
            MFMGPL+AS +W+ +GL G  +FL+++     R+ +++ I +++ +              
Sbjct  638  MFMGPLDASIAWSEEGLEGSRKFLDRVY----RLITTKEITEENSG--------------  679

Query  722  MYALETLLHRTIQKVTDDTSALSFNTAISQMMIFVNEATRVARRMPLPSKMWEMFVKILS  781
              AL+ + + T++ VT++   + FNTAI+Q+M+FVN A +  +  +  +K    FV++++
Sbjct  680  --ALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAK---GFVQLIA  734

Query  782  PYAPHLAEELWE-MCGHTHTIAYEPWPQVDPARVAPHVCSVVVQVNGKVRDTFSVAPNAP  840
            P+APHL+EELW+ + +  ++I+Y PWP  D +++  +   +VVQ++GKV+  + VA + +
Sbjct  735  PFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLS  794

Query  841  NEELEQKARETAGARKFLGTQQPKRVVIVPNKLVNFVL  878
             EEL++ A      +  ++ ++  +V+ VPNKLVN+V+
Sbjct  795  REELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

487) leuS in NC_017268


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  715 bits (2706),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 440/878 (51%), Positives = 610/878 (70%), Gaps = 51/878 (5%)

Query  12   YPFRALEKKWQAYWRDKRVFCVSEDERFPPERRAYVLDMFPYPSAQGLHVGHPEGYTATD  71
            Y   A+E KWQA+W D++ F  + D   ++  + Y LDMFPYPS+ GLHVGHPEGYTATD
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTD---ASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  72   IYCRYLRMGGYNVLHPMGFDAFGLPAENFALKTGTHPRVSTSANCDTFRRQIQSFGFSYD  131
            I  R+ R  G NVLHPMG DAFGLPAE++A+ TG +P   T+ N   F+RQI+++GFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  132  WEREISTADPEYYRWTQWLFLKLYEKGLAYEATAPINWCPSCKTGLANEEV-RDACCERC  190
            W+RE++T+DP+YY+WTQW+F KLYEKGLAYEA  P+NW     T++ANEEV  D+  ER 
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  191  GAEVTRRGVRQWMVRITAYAERLLSDLDELDWPESVKQMQRNWIGKSCGAEIDFPVDAPA  250
            G  V R+ +RQWM++ITAYAERLL DL+E+DWPES+K+MQRNWIGKS GA++ F V    
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  251  CSVHDKLPQTIRVYTTRADTLFGVTYLVLAPEHEAVTALTTHaqraavqayvqraaKKND  310
                    + + V+TTR+DTLFG TY VLAPEH  V A+TT  Q  AV  Y ++A+ K+D
Sbjct  241  --------KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSD  292

Query  311  LERTDLAKEKTGVFTGAYVRNPINDMRIPVWVGDYVLVSYGTGAVMAVPAHDQRDWDFAT  370
            L RTDLAKEKTGV TG+Y  NP+N+  +PVW++DYVL SYGTGA+MAVPAHD+RDW+FA 
Sbjct  293  LARTDLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAK  352

Query  371  RFGLPKLTVVSADYTATVPNSNSPQGAVLQRCVSDEGFVVNSGAFNGLASADARERIVAH  430
            +F L  + V+ +             G V +   +++G+ +NS+ ++GL  A A  ++V  
Sbjct  353  QFNLDIIPVLEG-------------GNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEW  399

Query  431  LEMRGAGARRVTYRLRDWVFSRQRYWGEPIPLVHCPSCGVVplpesalplllpeTADFTP  490
            LE  G G   VTYRLRDW+FSRQRYWGEPIP++H       ++PES LPL+LP T D+ P
Sbjct  400  LEAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRP  459

Query  491  TEDGQGPLARARTWLRVPCPQCASDAVRETNTMPQWAGSCWYYLRYMDPRNKTAFCAPEK  550
            +  G++PLA    WL V   + +  + RETNTMPQWAGS WYYLRY+DP+N   +   E 
Sbjct  460  SGTGESPLANVTDWLEV-TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEEL  518

Query  551  ERYWAPVALYVGGAEHAVLHLLYARFWHKVLYDLGLVSTKEPFARLVNQGMITSYAYRRK  610
             + W PV +YVGGAEHAVLHLLYARFWHKVLYDLG+V+TKEPF +L NQGMI + +YR  
Sbjct  519  LKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDS  578

Query  611  NGALVPHDEVHTNAQGTYVHARTGEKLECVVAKMSKALKNVVNPDDMIAAYGADACRVYE  670
             GALV+ D V+   +G++ H  TGE LE   AKMSK+LKNVVNPDD++  YGAD+ RVYE
Sbjct  579  RGALVATDKVEKR-DGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYE  637

Query  671  MFMGPLEASKPWNTQGLVGVFRFLEKIWVLAGRVAAANGIPQDSRAEPPGDLHAQKKSCS  730
            MFMGPL+AS +W+ +GL G  +FL+++     R+ +++ I +++ +              
Sbjct  638  MFMGPLDASIAWSEEGLEGSRKFLDRVY----RLITTKEITEENSG--------------  679

Query  731  MYALETLLHRTIQKVTDDTSALSFNTAISQMMIFVNEATRVARRMPLPSKMWEMFVKILS  790
              AL+ + + T++ VT++   + FNTAI+Q+M+FVN A +  +  +  +K    FV++++
Sbjct  680  --ALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAK---GFVQLIA  734

Query  791  PYAPHLAEELWE-MCGHTHTIAYEPWPQVDPARVAPHVCSVVVQVNGKVRDTFSVAPNAP  849
            P+APHL+EELW+ + +  ++I+Y PWP  D +++  +   +VVQ++GKV+  + VA + +
Sbjct  735  PFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLS  794

Query  850  NEELEQKARETAGARKFLGTQQPKRVVIVPNKLVNFVL  887
             EEL++ A      +  ++ ++  +V+ VPNKLVN+V+
Sbjct  795  REELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

488) leuS in NC_016844


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  715 bits (2706),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 440/878 (51%), Positives = 610/878 (70%), Gaps = 51/878 (5%)

Query  3    YPFRALEKKWQAYWRDKRVFCVSEDERFPPERRAYVLDMFPYPSAQGLHVGHPEGYTATD  62
            Y   A+E KWQA+W D++ F  + D   ++  + Y LDMFPYPS+ GLHVGHPEGYTATD
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTD---ASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  63   IYCRYLRMGGYNVLHPMGFDAFGLPAENFALKTGTHPRVSTSANCDTFRRQIQSFGFSYD  122
            I  R+ R  G NVLHPMG DAFGLPAE++A+ TG +P   T+ N   F+RQI+++GFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  123  WEREISTADPEYYRWTQWLFLKLYEKGLAYEATAPINWCPSCKTGLANEEV-RDACCERC  181
            W+RE++T+DP+YY+WTQW+F KLYEKGLAYEA  P+NW     T++ANEEV  D+  ER 
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  182  GAEVTRRGVRQWMVRITAYAERLLSDLDELDWPESVKQMQRNWIGKSCGAEIDFPVDAPA  241
            G  V R+ +RQWM++ITAYAERLL DL+E+DWPES+K+MQRNWIGKS GA++ F V    
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  242  CSVHDKLPQTIRVYTTRADTLFGVTYLVLAPEHEAVTALTTHaqraavqayvqraaKKND  301
                    + + V+TTR+DTLFG TY VLAPEH  V A+TT  Q  AV  Y ++A+ K+D
Sbjct  241  --------KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSD  292

Query  302  LERTDLAKEKTGVFTGAYVRNPINDMRIPVWVGDYVLVSYGTGAVMAVPAHDQRDWDFAT  361
            L RTDLAKEKTGV TG+Y  NP+N+  +PVW++DYVL SYGTGA+MAVPAHD+RDW+FA 
Sbjct  293  LARTDLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAK  352

Query  362  RFGLPKLTVVSADYTATVPNSNSPQGAVLQRCVSDEGFVVNSGAFNGLASADARERIVAH  421
            +F L  + V+ +             G V +   +++G+ +NS+ ++GL  A A  ++V  
Sbjct  353  QFNLDIIPVLEG-------------GNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEW  399

Query  422  LEMRGAGARRVTYRLRDWVFSRQRYWGEPIPLVHCPSCGVVplpesalplllpeTADFTP  481
            LE  G G   VTYRLRDW+FSRQRYWGEPIP++H       ++PES LPL+LP T D+ P
Sbjct  400  LEAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRP  459

Query  482  TEDGQGPLARARTWLRVPCPQCASDAVRETNTMPQWAGSCWYYLRYMDPRNKTAFCAPEK  541
            +  G++PLA    WL V   + +  + RETNTMPQWAGS WYYLRY+DP+N   +   E 
Sbjct  460  SGTGESPLANVTDWLEV-TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEEL  518

Query  542  ERYWAPVALYVGGAEHAVLHLLYARFWHKVLYDLGLVSTKEPFARLVNQGMITSYAYRRK  601
             + W PV +YVGGAEHAVLHLLYARFWHKVLYDLG+V+TKEPF +L NQGMI + +YR  
Sbjct  519  LKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDS  578

Query  602  NGALVPHDEVHTNAQGTYVHARTGEKLECVVAKMSKALKNVVNPDDMIAAYGADACRVYE  661
             GALV+ D V+   +G++ H  TGE LE   AKMSK+LKNVVNPDD++  YGAD+ RVYE
Sbjct  579  RGALVATDKVEKR-DGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYE  637

Query  662  MFMGPLEASKPWNTQGLVGVFRFLEKIWVLAGRVAAANGIPQDSRAEPPGDLHAQKKSCS  721
            MFMGPL+AS +W+ +GL G  +FL+++     R+ +++ I +++ +              
Sbjct  638  MFMGPLDASIAWSEEGLEGSRKFLDRVY----RLITTKEITEENSG--------------  679

Query  722  MYALETLLHRTIQKVTDDTSALSFNTAISQMMIFVNEATRVARRMPLPSKMWEMFVKILS  781
              AL+ + + T++ VT++   + FNTAI+Q+M+FVN A +  +  +  +K    FV++++
Sbjct  680  --ALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAK---GFVQLIA  734

Query  782  PYAPHLAEELWE-MCGHTHTIAYEPWPQVDPARVAPHVCSVVVQVNGKVRDTFSVAPNAP  840
            P+APHL+EELW+ + +  ++I+Y PWP  D +++  +   +VVQ++GKV+  + VA + +
Sbjct  735  PFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLS  794

Query  841  NEELEQKARETAGARKFLGTQQPKRVVIVPNKLVNFVL  878
             EEL++ A      +  ++ ++  +V+ VPNKLVN+V+
Sbjct  795  REELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

489) leuS in NC_018722


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  715 bits (2706),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 440/878 (51%), Positives = 610/878 (70%), Gaps = 51/878 (5%)

Query  3    YPFRALEKKWQAYWRDKRVFCVSEDERFPPERRAYVLDMFPYPSAQGLHVGHPEGYTATD  62
            Y   A+E KWQA+W D++ F  + D   ++  + Y LDMFPYPS+ GLHVGHPEGYTATD
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTD---ASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  63   IYCRYLRMGGYNVLHPMGFDAFGLPAENFALKTGTHPRVSTSANCDTFRRQIQSFGFSYD  122
            I  R+ R  G NVLHPMG DAFGLPAE++A+ TG +P   T+ N   F+RQI+++GFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  123  WEREISTADPEYYRWTQWLFLKLYEKGLAYEATAPINWCPSCKTGLANEEV-RDACCERC  181
            W+RE++T+DP+YY+WTQW+F KLYEKGLAYEA  P+NW     T++ANEEV  D+  ER 
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  182  GAEVTRRGVRQWMVRITAYAERLLSDLDELDWPESVKQMQRNWIGKSCGAEIDFPVDAPA  241
            G  V R+ +RQWM++ITAYAERLL DL+E+DWPES+K+MQRNWIGKS GA++ F V    
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  242  CSVHDKLPQTIRVYTTRADTLFGVTYLVLAPEHEAVTALTTHaqraavqayvqraaKKND  301
                    + + V+TTR+DTLFG TY VLAPEH  V A+TT  Q  AV  Y ++A+ K+D
Sbjct  241  --------KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSD  292

Query  302  LERTDLAKEKTGVFTGAYVRNPINDMRIPVWVGDYVLVSYGTGAVMAVPAHDQRDWDFAT  361
            L RTDLAKEKTGV TG+Y  NP+N+  +PVW++DYVL SYGTGA+MAVPAHD+RDW+FA 
Sbjct  293  LARTDLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAK  352

Query  362  RFGLPKLTVVSADYTATVPNSNSPQGAVLQRCVSDEGFVVNSGAFNGLASADARERIVAH  421
            +F L  + V+ +             G V +   +++G+ +NS+ ++GL  A A  ++V  
Sbjct  353  QFNLDIIPVLEG-------------GNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEW  399

Query  422  LEMRGAGARRVTYRLRDWVFSRQRYWGEPIPLVHCPSCGVVplpesalplllpeTADFTP  481
            LE  G G   VTYRLRDW+FSRQRYWGEPIP++H       ++PES LPL+LP T D+ P
Sbjct  400  LEAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRP  459

Query  482  TEDGQGPLARARTWLRVPCPQCASDAVRETNTMPQWAGSCWYYLRYMDPRNKTAFCAPEK  541
            +  G++PLA    WL V   + +  + RETNTMPQWAGS WYYLRY+DP+N   +   E 
Sbjct  460  SGTGESPLANVTDWLEV-TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEEL  518

Query  542  ERYWAPVALYVGGAEHAVLHLLYARFWHKVLYDLGLVSTKEPFARLVNQGMITSYAYRRK  601
             + W PV +YVGGAEHAVLHLLYARFWHKVLYDLG+V+TKEPF +L NQGMI + +YR  
Sbjct  519  LKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDS  578

Query  602  NGALVPHDEVHTNAQGTYVHARTGEKLECVVAKMSKALKNVVNPDDMIAAYGADACRVYE  661
             GALV+ D V+   +G++ H  TGE LE   AKMSK+LKNVVNPDD++  YGAD+ RVYE
Sbjct  579  RGALVATDKVEKR-DGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYE  637

Query  662  MFMGPLEASKPWNTQGLVGVFRFLEKIWVLAGRVAAANGIPQDSRAEPPGDLHAQKKSCS  721
            MFMGPL+AS +W+ +GL G  +FL+++     R+ +++ I +++ +              
Sbjct  638  MFMGPLDASIAWSEEGLEGSRKFLDRVY----RLITTKEITEENSG--------------  679

Query  722  MYALETLLHRTIQKVTDDTSALSFNTAISQMMIFVNEATRVARRMPLPSKMWEMFVKILS  781
              AL+ + + T++ VT++   + FNTAI+Q+M+FVN A +  +  +  +K    FV++++
Sbjct  680  --ALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAK---GFVQLIA  734

Query  782  PYAPHLAEELWE-MCGHTHTIAYEPWPQVDPARVAPHVCSVVVQVNGKVRDTFSVAPNAP  840
            P+APHL+EELW+ + +  ++I+Y PWP  D +++  +   +VVQ++GKV+  + VA + +
Sbjct  735  PFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLS  794

Query  841  NEELEQKARETAGARKFLGTQQPKRVVIVPNKLVNFVL  878
             EEL++ A      +  ++ ++  +V+ VPNKLVN+V+
Sbjct  795  REELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

490) leuS in NC_021490


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  715 bits (2706),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 440/878 (51%), Positives = 610/878 (70%), Gaps = 51/878 (5%)

Query  3    YPFRALEKKWQAYWRDKRVFCVSEDERFPPERRAYVLDMFPYPSAQGLHVGHPEGYTATD  62
            Y   A+E KWQA+W D++ F  + D   ++  + Y LDMFPYPS+ GLHVGHPEGYTATD
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTD---ASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  63   IYCRYLRMGGYNVLHPMGFDAFGLPAENFALKTGTHPRVSTSANCDTFRRQIQSFGFSYD  122
            I  R+ R  G NVLHPMG DAFGLPAE++A+ TG +P   T+ N   F+RQI+++GFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  123  WEREISTADPEYYRWTQWLFLKLYEKGLAYEATAPINWCPSCKTGLANEEV-RDACCERC  181
            W+RE++T+DP+YY+WTQW+F KLYEKGLAYEA  P+NW     T++ANEEV  D+  ER 
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  182  GAEVTRRGVRQWMVRITAYAERLLSDLDELDWPESVKQMQRNWIGKSCGAEIDFPVDAPA  241
            G  V R+ +RQWM++ITAYAERLL DL+E+DWPES+K+MQRNWIGKS GA++ F V    
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  242  CSVHDKLPQTIRVYTTRADTLFGVTYLVLAPEHEAVTALTTHaqraavqayvqraaKKND  301
                    + + V+TTR+DTLFG TY VLAPEH  V A+TT  Q  AV  Y ++A+ K+D
Sbjct  241  --------KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSD  292

Query  302  LERTDLAKEKTGVFTGAYVRNPINDMRIPVWVGDYVLVSYGTGAVMAVPAHDQRDWDFAT  361
            L RTDLAKEKTGV TG+Y  NP+N+  +PVW++DYVL SYGTGA+MAVPAHD+RDW+FA 
Sbjct  293  LARTDLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAK  352

Query  362  RFGLPKLTVVSADYTATVPNSNSPQGAVLQRCVSDEGFVVNSGAFNGLASADARERIVAH  421
            +F L  + V+ +             G V +   +++G+ +NS+ ++GL  A A  ++V  
Sbjct  353  QFNLDIIPVLEG-------------GNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEW  399

Query  422  LEMRGAGARRVTYRLRDWVFSRQRYWGEPIPLVHCPSCGVVplpesalplllpeTADFTP  481
            LE  G G   VTYRLRDW+FSRQRYWGEPIP++H       ++PES LPL+LP T D+ P
Sbjct  400  LEAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRP  459

Query  482  TEDGQGPLARARTWLRVPCPQCASDAVRETNTMPQWAGSCWYYLRYMDPRNKTAFCAPEK  541
            +  G++PLA    WL V   + +  + RETNTMPQWAGS WYYLRY+DP+N   +   E 
Sbjct  460  SGTGESPLANVTDWLEV-TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEEL  518

Query  542  ERYWAPVALYVGGAEHAVLHLLYARFWHKVLYDLGLVSTKEPFARLVNQGMITSYAYRRK  601
             + W PV +YVGGAEHAVLHLLYARFWHKVLYDLG+V+TKEPF +L NQGMI + +YR  
Sbjct  519  LKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDS  578

Query  602  NGALVPHDEVHTNAQGTYVHARTGEKLECVVAKMSKALKNVVNPDDMIAAYGADACRVYE  661
             GALV+ D V+   +G++ H  TGE LE   AKMSK+LKNVVNPDD++  YGAD+ RVYE
Sbjct  579  RGALVATDKVEKR-DGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYE  637

Query  662  MFMGPLEASKPWNTQGLVGVFRFLEKIWVLAGRVAAANGIPQDSRAEPPGDLHAQKKSCS  721
            MFMGPL+AS +W+ +GL G  +FL+++     R+ +++ I +++ +              
Sbjct  638  MFMGPLDASIAWSEEGLEGSRKFLDRVY----RLITTKEITEENSG--------------  679

Query  722  MYALETLLHRTIQKVTDDTSALSFNTAISQMMIFVNEATRVARRMPLPSKMWEMFVKILS  781
              AL+ + + T++ VT++   + FNTAI+Q+M+FVN A +  +  +  +K    FV++++
Sbjct  680  --ALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAK---GFVQLIA  734

Query  782  PYAPHLAEELWE-MCGHTHTIAYEPWPQVDPARVAPHVCSVVVQVNGKVRDTFSVAPNAP  840
            P+APHL+EELW+ + +  ++I+Y PWP  D +++  +   +VVQ++GKV+  + VA + +
Sbjct  735  PFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLS  794

Query  841  NEELEQKARETAGARKFLGTQQPKRVVIVPNKLVNFVL  878
             EEL++ A      +  ++ ++  +V+ VPNKLVN+V+
Sbjct  795  REELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

491) leuS in NC_000919


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  715 bits (2706),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 440/878 (51%), Positives = 610/878 (70%), Gaps = 51/878 (5%)

Query  3    YPFRALEKKWQAYWRDKRVFCVSEDERFPPERRAYVLDMFPYPSAQGLHVGHPEGYTATD  62
            Y   A+E KWQA+W D++ F  + D   ++  + Y LDMFPYPS+ GLHVGHPEGYTATD
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTD---ASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  63   IYCRYLRMGGYNVLHPMGFDAFGLPAENFALKTGTHPRVSTSANCDTFRRQIQSFGFSYD  122
            I  R+ R  G NVLHPMG DAFGLPAE++A+ TG +P   T+ N   F+RQI+++GFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  123  WEREISTADPEYYRWTQWLFLKLYEKGLAYEATAPINWCPSCKTGLANEEV-RDACCERC  181
            W+RE++T+DP+YY+WTQW+F KLYEKGLAYEA  P+NW     T++ANEEV  D+  ER 
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  182  GAEVTRRGVRQWMVRITAYAERLLSDLDELDWPESVKQMQRNWIGKSCGAEIDFPVDAPA  241
            G  V R+ +RQWM++ITAYAERLL DL+E+DWPES+K+MQRNWIGKS GA++ F V    
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  242  CSVHDKLPQTIRVYTTRADTLFGVTYLVLAPEHEAVTALTTHaqraavqayvqraaKKND  301
                    + + V+TTR+DTLFG TY VLAPEH  V A+TT  Q  AV  Y ++A+ K+D
Sbjct  241  --------KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSD  292

Query  302  LERTDLAKEKTGVFTGAYVRNPINDMRIPVWVGDYVLVSYGTGAVMAVPAHDQRDWDFAT  361
            L RTDLAKEKTGV TG+Y  NP+N+  +PVW++DYVL SYGTGA+MAVPAHD+RDW+FA 
Sbjct  293  LARTDLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAK  352

Query  362  RFGLPKLTVVSADYTATVPNSNSPQGAVLQRCVSDEGFVVNSGAFNGLASADARERIVAH  421
            +F L  + V+ +             G V +   +++G+ +NS+ ++GL  A A  ++V  
Sbjct  353  QFNLDIIPVLEG-------------GNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEW  399

Query  422  LEMRGAGARRVTYRLRDWVFSRQRYWGEPIPLVHCPSCGVVplpesalplllpeTADFTP  481
            LE  G G   VTYRLRDW+FSRQRYWGEPIP++H       ++PES LPL+LP T D+ P
Sbjct  400  LEAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRP  459

Query  482  TEDGQGPLARARTWLRVPCPQCASDAVRETNTMPQWAGSCWYYLRYMDPRNKTAFCAPEK  541
            +  G++PLA    WL V   + +  + RETNTMPQWAGS WYYLRY+DP+N   +   E 
Sbjct  460  SGTGESPLANVTDWLEV-TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEEL  518

Query  542  ERYWAPVALYVGGAEHAVLHLLYARFWHKVLYDLGLVSTKEPFARLVNQGMITSYAYRRK  601
             + W PV +YVGGAEHAVLHLLYARFWHKVLYDLG+V+TKEPF +L NQGMI + +YR  
Sbjct  519  LKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDS  578

Query  602  NGALVPHDEVHTNAQGTYVHARTGEKLECVVAKMSKALKNVVNPDDMIAAYGADACRVYE  661
             GALV+ D V+   +G++ H  TGE LE   AKMSK+LKNVVNPDD++  YGAD+ RVYE
Sbjct  579  RGALVATDKVEKR-DGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYE  637

Query  662  MFMGPLEASKPWNTQGLVGVFRFLEKIWVLAGRVAAANGIPQDSRAEPPGDLHAQKKSCS  721
            MFMGPL+AS +W+ +GL G  +FL+++     R+ +++ I +++ +              
Sbjct  638  MFMGPLDASIAWSEEGLEGSRKFLDRVY----RLITTKEITEENSG--------------  679

Query  722  MYALETLLHRTIQKVTDDTSALSFNTAISQMMIFVNEATRVARRMPLPSKMWEMFVKILS  781
              AL+ + + T++ VT++   + FNTAI+Q+M+FVN A +  +  +  +K    FV++++
Sbjct  680  --ALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAK---GFVQLIA  734

Query  782  PYAPHLAEELWE-MCGHTHTIAYEPWPQVDPARVAPHVCSVVVQVNGKVRDTFSVAPNAP  840
            P+APHL+EELW+ + +  ++I+Y PWP  D +++  +   +VVQ++GKV+  + VA + +
Sbjct  735  PFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLS  794

Query  841  NEELEQKARETAGARKFLGTQQPKRVVIVPNKLVNFVL  878
             EEL++ A      +  ++ ++  +V+ VPNKLVN+V+
Sbjct  795  REELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

492) leuS in NC_010741


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  715 bits (2706),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 440/878 (51%), Positives = 610/878 (70%), Gaps = 51/878 (5%)

Query  3    YPFRALEKKWQAYWRDKRVFCVSEDERFPPERRAYVLDMFPYPSAQGLHVGHPEGYTATD  62
            Y   A+E KWQA+W D++ F  + D   ++  + Y LDMFPYPS+ GLHVGHPEGYTATD
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTD---ASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  63   IYCRYLRMGGYNVLHPMGFDAFGLPAENFALKTGTHPRVSTSANCDTFRRQIQSFGFSYD  122
            I  R+ R  G NVLHPMG DAFGLPAE++A+ TG +P   T+ N   F+RQI+++GFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  123  WEREISTADPEYYRWTQWLFLKLYEKGLAYEATAPINWCPSCKTGLANEEV-RDACCERC  181
            W+RE++T+DP+YY+WTQW+F KLYEKGLAYEA  P+NW     T++ANEEV  D+  ER 
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  182  GAEVTRRGVRQWMVRITAYAERLLSDLDELDWPESVKQMQRNWIGKSCGAEIDFPVDAPA  241
            G  V R+ +RQWM++ITAYAERLL DL+E+DWPES+K+MQRNWIGKS GA++ F V    
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  242  CSVHDKLPQTIRVYTTRADTLFGVTYLVLAPEHEAVTALTTHaqraavqayvqraaKKND  301
                    + + V+TTR+DTLFG TY VLAPEH  V A+TT  Q  AV  Y ++A+ K+D
Sbjct  241  --------KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSD  292

Query  302  LERTDLAKEKTGVFTGAYVRNPINDMRIPVWVGDYVLVSYGTGAVMAVPAHDQRDWDFAT  361
            L RTDLAKEKTGV TG+Y  NP+N+  +PVW++DYVL SYGTGA+MAVPAHD+RDW+FA 
Sbjct  293  LARTDLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAK  352

Query  362  RFGLPKLTVVSADYTATVPNSNSPQGAVLQRCVSDEGFVVNSGAFNGLASADARERIVAH  421
            +F L  + V+ +             G V +   +++G+ +NS+ ++GL  A A  ++V  
Sbjct  353  QFNLDIIPVLEG-------------GNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEW  399

Query  422  LEMRGAGARRVTYRLRDWVFSRQRYWGEPIPLVHCPSCGVVplpesalplllpeTADFTP  481
            LE  G G   VTYRLRDW+FSRQRYWGEPIP++H       ++PES LPL+LP T D+ P
Sbjct  400  LEAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRP  459

Query  482  TEDGQGPLARARTWLRVPCPQCASDAVRETNTMPQWAGSCWYYLRYMDPRNKTAFCAPEK  541
            +  G++PLA    WL V   + +  + RETNTMPQWAGS WYYLRY+DP+N   +   E 
Sbjct  460  SGTGESPLANVTDWLEV-TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEEL  518

Query  542  ERYWAPVALYVGGAEHAVLHLLYARFWHKVLYDLGLVSTKEPFARLVNQGMITSYAYRRK  601
             + W PV +YVGGAEHAVLHLLYARFWHKVLYDLG+V+TKEPF +L NQGMI + +YR  
Sbjct  519  LKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDS  578

Query  602  NGALVPHDEVHTNAQGTYVHARTGEKLECVVAKMSKALKNVVNPDDMIAAYGADACRVYE  661
             GALV+ D V+   +G++ H  TGE LE   AKMSK+LKNVVNPDD++  YGAD+ RVYE
Sbjct  579  RGALVATDKVEKR-DGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYE  637

Query  662  MFMGPLEASKPWNTQGLVGVFRFLEKIWVLAGRVAAANGIPQDSRAEPPGDLHAQKKSCS  721
            MFMGPL+AS +W+ +GL G  +FL+++     R+ +++ I +++ +              
Sbjct  638  MFMGPLDASIAWSEEGLEGSRKFLDRVY----RLITTKEITEENSG--------------  679

Query  722  MYALETLLHRTIQKVTDDTSALSFNTAISQMMIFVNEATRVARRMPLPSKMWEMFVKILS  781
              AL+ + + T++ VT++   + FNTAI+Q+M+FVN A +  +  +  +K    FV++++
Sbjct  680  --ALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAK---GFVQLIA  734

Query  782  PYAPHLAEELWE-MCGHTHTIAYEPWPQVDPARVAPHVCSVVVQVNGKVRDTFSVAPNAP  840
            P+APHL+EELW+ + +  ++I+Y PWP  D +++  +   +VVQ++GKV+  + VA + +
Sbjct  735  PFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLS  794

Query  841  NEELEQKARETAGARKFLGTQQPKRVVIVPNKLVNFVL  878
             EEL++ A      +  ++ ++  +V+ VPNKLVN+V+
Sbjct  795  REELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

493) leuS in NC_021508


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  715 bits (2706),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 440/878 (51%), Positives = 610/878 (70%), Gaps = 51/878 (5%)

Query  3    YPFRALEKKWQAYWRDKRVFCVSEDERFPPERRAYVLDMFPYPSAQGLHVGHPEGYTATD  62
            Y   A+E KWQA+W D++ F  + D   ++  + Y LDMFPYPS+ GLHVGHPEGYTATD
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTD---ASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  63   IYCRYLRMGGYNVLHPMGFDAFGLPAENFALKTGTHPRVSTSANCDTFRRQIQSFGFSYD  122
            I  R+ R  G NVLHPMG DAFGLPAE++A+ TG +P   T+ N   F+RQI+++GFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  123  WEREISTADPEYYRWTQWLFLKLYEKGLAYEATAPINWCPSCKTGLANEEV-RDACCERC  181
            W+RE++T+DP+YY+WTQW+F KLYEKGLAYEA  P+NW     T++ANEEV  D+  ER 
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  182  GAEVTRRGVRQWMVRITAYAERLLSDLDELDWPESVKQMQRNWIGKSCGAEIDFPVDAPA  241
            G  V R+ +RQWM++ITAYAERLL DL+E+DWPES+K+MQRNWIGKS GA++ F V    
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  242  CSVHDKLPQTIRVYTTRADTLFGVTYLVLAPEHEAVTALTTHaqraavqayvqraaKKND  301
                    + + V+TTR+DTLFG TY VLAPEH  V A+TT  Q  AV  Y ++A+ K+D
Sbjct  241  --------KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSD  292

Query  302  LERTDLAKEKTGVFTGAYVRNPINDMRIPVWVGDYVLVSYGTGAVMAVPAHDQRDWDFAT  361
            L RTDLAKEKTGV TG+Y  NP+N+  +PVW++DYVL SYGTGA+MAVPAHD+RDW+FA 
Sbjct  293  LARTDLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAK  352

Query  362  RFGLPKLTVVSADYTATVPNSNSPQGAVLQRCVSDEGFVVNSGAFNGLASADARERIVAH  421
            +F L  + V+ +             G V +   +++G+ +NS+ ++GL  A A  ++V  
Sbjct  353  QFNLDIIPVLEG-------------GNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEW  399

Query  422  LEMRGAGARRVTYRLRDWVFSRQRYWGEPIPLVHCPSCGVVplpesalplllpeTADFTP  481
            LE  G G   VTYRLRDW+FSRQRYWGEPIP++H       ++PES LPL+LP T D+ P
Sbjct  400  LEAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRP  459

Query  482  TEDGQGPLARARTWLRVPCPQCASDAVRETNTMPQWAGSCWYYLRYMDPRNKTAFCAPEK  541
            +  G++PLA    WL V   + +  + RETNTMPQWAGS WYYLRY+DP+N   +   E 
Sbjct  460  SGTGESPLANVTDWLEV-TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEEL  518

Query  542  ERYWAPVALYVGGAEHAVLHLLYARFWHKVLYDLGLVSTKEPFARLVNQGMITSYAYRRK  601
             + W PV +YVGGAEHAVLHLLYARFWHKVLYDLG+V+TKEPF +L NQGMI + +YR  
Sbjct  519  LKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDS  578

Query  602  NGALVPHDEVHTNAQGTYVHARTGEKLECVVAKMSKALKNVVNPDDMIAAYGADACRVYE  661
             GALV+ D V+   +G++ H  TGE LE   AKMSK+LKNVVNPDD++  YGAD+ RVYE
Sbjct  579  RGALVATDKVEKR-DGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYE  637

Query  662  MFMGPLEASKPWNTQGLVGVFRFLEKIWVLAGRVAAANGIPQDSRAEPPGDLHAQKKSCS  721
            MFMGPL+AS +W+ +GL G  +FL+++     R+ +++ I +++ +              
Sbjct  638  MFMGPLDASIAWSEEGLEGSRKFLDRVY----RLITTKEITEENSG--------------  679

Query  722  MYALETLLHRTIQKVTDDTSALSFNTAISQMMIFVNEATRVARRMPLPSKMWEMFVKILS  781
              AL+ + + T++ VT++   + FNTAI+Q+M+FVN A +  +  +  +K    FV++++
Sbjct  680  --ALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAK---GFVQLIA  734

Query  782  PYAPHLAEELWE-MCGHTHTIAYEPWPQVDPARVAPHVCSVVVQVNGKVRDTFSVAPNAP  840
            P+APHL+EELW+ + +  ++I+Y PWP  D +++  +   +VVQ++GKV+  + VA + +
Sbjct  735  PFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLS  794

Query  841  NEELEQKARETAGARKFLGTQQPKRVVIVPNKLVNFVL  878
             EEL++ A      +  ++ ++  +V+ VPNKLVN+V+
Sbjct  795  REELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

494) leuS in NC_021284


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  714 bits (2701),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 449/825 (55%), Positives = 589/825 (72%), Gaps = 46/825 (5%)

Query  3    FSHKAIEQKWQKYWAE-HntfatntnfnkkaYILDMFPYPSGAGLHVGHPKGYTATDVIS  61
            + H AIE KWQ +WA+ H   +     + K Y LDMFPYPSGAGLHVGHP GYTATD++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  62   RMRRLQQYNVLHPIGWDAFGLPAEQYALQTGNDPADFTLKNIDNFRNQLKALGFSYDYQK  121
            R +R Q  NVLHP+GWDAFGLPAEQYA++TGNDPA+FT  NI NF+ Q++ALGFSYD ++
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  122  EVNTSAPWYFKTTQWIFEKLYQQGLAEVREVDVNWCPELGTVLANEEVFVVDGKMVSERG  181
            EVNT+ P Y+K TQWIF KLY++GLA   EV VNW  ELGT +ANEEV + DG   SERG
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEV-LPDG--TSERG  180

Query  182  SFPVYKKPMKQWVLKITAYAEQLISGLDELDWPQSVKDLQKNWIGKSVGAEIKFAVADMS  241
            ++PV +KPM+QW+LKITAYAE+L+ +L+E+DWP+S+KD+Q+NWIGKS GA++ F V D  
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  242  EEVTVFSTRADTIFGVEYLVLAPEHPLVLSLVTPENLAATKEYLELVKTKTELDRQDTSK  301
             + TVF+TR+DT+FG  Y VLAPEH+LV ++ T+++  A  +Y      K++L R D +K
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  302  EKTGVFLGRYAINPVNNKKIPIWTADYVLSHYGTGAVMAVPGHDERDYLFAMKYNLPISY  361
            EKTGV  G YAINPVN K +P+W ADYVL+ YGTGA+MAVP+HDERD  FA ++NL I  
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  362  VIKNNN-NNGPFLKDGEHINSDFLDGLNTDQASEkalgflggkglaQPKVTYKLKDWLFS  420
            V+   N ++++F  DG HINSDFLDGL+   A  K +  L + G+++ +VTY+L+DWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  421  RQRYWGEPFPIIHWEDGSISLVPEAELPLTLPKMDNITPSSTGESPLANATDWLTVVDAT  480
            RQRYWGEP+PIIHWEDG+ + VPE+ELPL LP   +I PS+TGESPLAN TDWL V    
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  481  GKKGRRETNTMPQWAGSCWYYLAYPLMTGQEEMLDLASPEGQAALKEWLPVDLYVGGQEH  540
            G KGRRETNTMPQWAGS WYYL Y      E + D      +  LK+WLPVD+YVGG EH
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLAD------EELLKQWLPVDIYVGGAEH  534

Query  541  AVLHLLYARFWHKVLFDQNLVPTSEPFIKLVNQGMILGPD--------------------  580
            AVLHLLYARFWHKVL+D  +VPT EPF KL NQGMILG                      
Sbjct  535  AVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGS  594

Query  581  -------------GSKMSKSKGNVINPDDIIKSHGADSLRLYEMFMGPIEASLPWSETGL  627
                          +KMSKS  NV+NPDD++   GAD+LR+YEMFMGP++AS++WSE GL
Sbjct  595  FFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGL  654

Query  628  DSMRKWLDRIYRLVKNNNFTTVNDKTLDFAYHQMVKKTTEMLENLSFNTAISQLMVFINA  687
            ++ RK LDR+YRL+  +++T  N  +LD  Y++ VK  TE ++++ FNTAI+QLMVF+NA
Sbjct  655  EGSRKFLDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNA  714

Query  688  CYKTDQPIYQPYFEGFTKILSCFAPHLAEEIWNNFGHQA-SIANEQWPIYETKYLQKTAI  746
              K D+ ++  Y  GF ++++ FAPHL+EE+W+ +   + SI+   WP Y+   L    +
Sbjct  715  ANKEDK-LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDV  773

Query  747  IVAVQVNGKLRAKLEVAVDTPeaellllakeheNIQGILATHDIL  791
             + VQ++GK++AKL VA D +  EL  +A  +E++Q+ +A  DI+
Sbjct  774  EIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDII  818

495) leuS in NC_015714


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  714 bits (2699),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 440/878 (51%), Positives = 609/878 (70%), Gaps = 51/878 (5%)

Query  3    YPFRALEKKWQAYWRDKRVFCVSEDERFPPERRAYVLDMFPYPSAQGLHVGHPEGYTATD  62
            Y   A+E KWQA+W D++ F  + D   ++  + Y LDMFPYPS+ GLHVGHPEGYTATD
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTD---ASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  63   IYCRYLRMGGYNVLHPMGFDAFGLPAENFALKTGTHPRVSTSANCDTFRRQIQSFGFSYD  122
            I  R+ R  G NVLHPMG DAFGLPAE++A+ TG +P   T+ N   F+RQI+++GFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  123  WEREISTADPEYYRWTQWLFLKLYEKGLAYEATAPINWCPSCKTGLANEEV-RDACCERC  181
            W+RE++T+DP+YY+WTQW+F KLYEKGLAYEA  P+NW     T++ANEEV  D+  ER 
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  182  GAEVTRRGVRQWMVRITAYAERLLSDLDELDWPESVKQMQRNWIGKSCGAEIDFPVDAPA  241
            G  V R+ +RQWM++ITAYAERLL DL+E+DWPES+K+MQRNWIGKS GA++ F V    
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  242  CSVHDKLPQTIRVYTTRADTLFGVTYLVLAPEHEAVTALTTHaqraavqayvqraaKKND  301
                    + + V+TTR+DTLFG TY VLAPEH  V A+TT  Q  AV  Y ++A+ K+D
Sbjct  241  --------KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSD  292

Query  302  LERTDLAKEKTGVFTGAYVRNPINDMRIPVWVGDYVLVSYGTGAVMAVPAHDQRDWDFAT  361
            L RTDLAKEKTGV TG+Y  NP+N+  +PVW++DYVL SYGTGA+MAVPAHD+RDW+FA 
Sbjct  293  LARTDLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAK  352

Query  362  RFGLPKLTVVSADYTATVPNSNSPQGAVLQRCVSDEGFVVNSGAFNGLASADARERIVAH  421
            +F L  + V+ +             G V +   +++G+ +NS+ ++GL  A A  ++V  
Sbjct  353  QFNLDIIPVLEG-------------GNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEW  399

Query  422  LEMRGAGARRVTYRLRDWVFSRQRYWGEPIPLVHCPSCGVVplpesalplllpeTADFTP  481
            LE  G G   VTYRLRDW+FSRQRYWGEPIP++H       ++PES LPL+LP T D+ P
Sbjct  400  LEAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRP  459

Query  482  TEDGQGPLARARMWLRVPCPQCASDAVRETNTMPQWAGSCWYYLRYMDPRNKTAFCAPEK  541
            +  G++PLA    WL V   + +  + RETNTMPQWAGS WYYLRY+DP+N   +   E 
Sbjct  460  SGTGESPLANVTDWLEV-TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEEL  518

Query  542  ERYWAPVALYVGGAEHAVLHLLYARFWHKVLYDLGLVSTKEPFARLVNQGMITSYAYRRK  601
             + W PV +YVGGAEHAVLHLLYARFWHKVLYDLG+V+TKEPF +L NQGMI + +YR  
Sbjct  519  LKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDS  578

Query  602  NGALVPHDEVHTNAQGTYVHARTGEKLECVVAKMSKALKNVVNPDDMIAAYGADACRVYE  661
             GALV+ D V+   +G++ H  TGE LE   AKMSK+LKNVVNPDD++  YGAD+ RVYE
Sbjct  579  RGALVATDKVEKR-DGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYE  637

Query  662  MFMGPLEASKPWNTQGLVGVFRFLEKIWVLAGRVAAANGIPQDSRTEPPGDLHAQKKSCS  721
            MFMGPL+AS +W+ +GL G  +FL+++     R+ +++ I +++                
Sbjct  638  MFMGPLDASIAWSEEGLEGSRKFLDRVY----RLITTKEITEENSG--------------  679

Query  722  MYALETLLHRTIQKVTDDTSALSFNTAISQMMIFVNEATRVARRMPLPSKMWEMFVKILS  781
              AL+ + + T++ VT++   + FNTAI+Q+M+FVN A +  +  +  +K    FV++++
Sbjct  680  --ALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAK---GFVQLIA  734

Query  782  PYAPHLAEELWE-MCGHTHTIAYEPWPQVDPARVAPHVCSVVVQVNGKVRDTFSVAPNAP  840
            P+APHL+EELW+ + +  ++I+Y PWP  D +++  +   +VVQ++GKV+  + VA + +
Sbjct  735  PFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLS  794

Query  841  NEELEQKARETAGARKFLGTQQPKRVVIVPNKLVNFVL  878
             EEL++ A      +  ++ ++  +V+ VPNKLVN+V+
Sbjct  795  REELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

496) leuS in NC_017521


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  713 bits (2698),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 429/840 (52%), Positives = 599/840 (72%), Gaps = 50/840 (5%)

Query  3    FSHKAIEKKWQKYWKENNVYKT-TDSNHKKAYVLDMFPYPSGAGLHVGHIKGYTATDVYS  61
            + H AIE KWQ +W +N+ +KT TD++  K Y LDMFPYPSGAGLHVGH  GYTATD+ S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  62   RFKRMQGYDVLHPIGWDAFGLPAEQYALKTGNDPRDFTLKNIENFKAQLVKMGFSYDYDK  121
            RFKR QG +VLHP+GWDAFGLPAEQYA+ TGNDP +FT  NI NFK Q+  +GFSYD D+
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  122  EINTADPNYYKVTQWIFKELYKKGLAENRNIDVNWCQELGTVLANDEIIEKDGLMVSERG  181
            E+NT+DPNYYK TQWIF  LY KGLA + ++ VNW +ELGT +AN+E++  +    SERG
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDG---TSERG  180

Query  182  EHPVVKRKMRQWVLKITDYADKLLKGLDNLDWPNSVKELQRNWIGKSEGCEINFKSNDI-  240
              PVV++ MRQW+LKIT YA++LL +L+++DWP+S+K++QRNWIGKS G ++ FK +D  
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  241  -NIPVFTTRADTVFGATYIVLAPENELVLKLTTPNKLNEVKKYIELTANKSEIERKDESK  299
             ++ VFTTR+DT+FGATY VLAPE+ LV  +TT+++ + V  Y   ++ KS++ R D +K
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  300  TKTGVFIGSYAINPLTKEQIQIWISDYVLNDYGSGAIMAVPAHDKRDWDFATKFNLPIRF  359
             KTGV  GSYAINP+   ++ +WI+DYVL  YG+GAIMAVPAHD RDW+FA +FNL I  
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  360  VISTKD-QSKAFVGEGKHINSDFLNDLDRIQSLQVIHNYIEKNNLGKKKTNYKLRDWLFS  418
            V+   + +  AF  +G HINSDFL++LD+  ++  + + +E + +G+ +  Y+LRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  419  RQRFYGEPFPVLYDKDNNIILVEDNNLPITLPKTDYIKPTNTGESPLANVKNWVNV-KIG  477
            RQR+ GEP+P++   D     V +++LP+ LP T  I+P+ TGESPLANV +W++V + +
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  478  DREYKRETNTMPQSAGSSWYFIAYVLANSKNNLIDLIGDESKKRLEKWLPVDLYIGGQEH  537
            +   +RETNTMPQ AGSSWY++ Y+ +++ ++L D         L +WLPVD+Y+GG EH
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLAD------EELLKQWLPVDIYVGGAEH  534

Query  538  AVGHLLYSRFWTHFLYDLGLLPTSEPFQRLFNQGMILGSDNR------------------  579
            AV HLLY+RFW   LYDLG++PT EPFQ+LFNQGMILG+  R                  
Sbjct  535  AVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGS  594

Query  580  ---------------KMSKSWGNVINPDDVIDTHGADALRLYEMFMGPLDASLPWSFDGL  624
                           KMSKS  NV+NPDDV++  GAD+LR+YEMFMGPLDAS++WS +GL
Sbjct  595  FFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGL  654

Query  625  DASLKWLNRCYRMINKVEFSNTNNHKLDYVYNDVVKKVTQMIKELKFNTAISQLMVLVNA  684
            ++S K L+R YR+I   E+++ N+  LD VYN+ VK VT+ + ++KFNTAI+QLMV+VNA
Sbjct  655  EGSRKFLDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNA  714

Query  685  IYKEELSTVYKPYIEGFVKMLSLFSPHLAEELWEKLGNRT-SVTLQTWPEFDETKIVKNT  743
              KE+   ++  Y  GFV++++ F+PHL+EELW+ L     S++   WP +DE+K+V N 
Sbjct  715  ANKED--KLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVEND  772

Query  744  VVIALQVNGKLRSTIEVEKGTDKEILIKLAQENENIIRFIKDHKNLKYIAVVDRIVNIVI  803
            V I +Q++GK+++ + V K+  +E L  +A  NE++   I +   +K IAV +++VNIVI
Sbjct  773  VEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

497) leuS in NC_014751


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  713 bits (2698),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 429/840 (52%), Positives = 599/840 (72%), Gaps = 50/840 (5%)

Query  3    FSHKAIEKKWQKYWKENNVYKT-TDSNHKKAYVLDMFPYPSGAGLHVGHIKGYTATDVYS  61
            + H AIE KWQ +W +N+ +KT TD++  K Y LDMFPYPSGAGLHVGH  GYTATD+ S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  62   RFKRMQGYDVLHPIGWDAFGLPAEQYALKTGNDPRDFTLKNIENFKAQLVKMGFSYDYDK  121
            RFKR QG +VLHP+GWDAFGLPAEQYA+ TGNDP +FT  NI NFK Q+  +GFSYD D+
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  122  EINTADPNYYKVTQWIFKELYKKGLAENRNIDVNWCQELGTVLANDEIIEKDGLMVSERG  181
            E+NT+DPNYYK TQWIF  LY KGLA + ++ VNW +ELGT +AN+E++  +    SERG
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDG---TSERG  180

Query  182  EHPVVKRKMRQWVLKITDYADKLLKGLDNLDWPNSVKELQRNWIGKSEGCEINFKSNDI-  240
              PVV++ MRQW+LKIT YA++LL +L+++DWP+S+K++QRNWIGKS G ++ FK +D  
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  241  -NIPVFTTRADTVFGATYIVLAPENELVLKLTTPNKLNEVKKYIELTANKSEIERKDESK  299
             ++ VFTTR+DT+FGATY VLAPE+ LV  +TT+++ + V  Y   ++ KS++ R D +K
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  300  TKTGVFIGSYAINPLTKEQIQIWISDYVLNDYGSGAIMAVPAHDKRDWDFATKFNLPIRF  359
             KTGV  GSYAINP+   ++ +WI+DYVL  YG+GAIMAVPAHD RDW+FA +FNL I  
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  360  VISTKD-QSKAFVGEGKHINSDFLNDLDRIQSLQVIHNYIEKNNLGKKKTNYKLRDWLFS  418
            V+   + +  AF  +G HINSDFL++LD+  ++  + + +E + +G+ +  Y+LRDWLFS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  419  RQRFYGEPFPVLYDKDNNIILVEDNNLPITLPKTDYIKPTNTGESPLANVKNWVNV-KIG  477
            RQR+ GEP+P++   D     V +++LP+ LP T  I+P+ TGESPLANV +W++V + +
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  478  DREYKRETNTMPQSAGSSWYFIAYVLANSKNNLIDLIGDESKKRLEKWLPVDLYIGGQEH  537
            +   +RETNTMPQ AGSSWY++ Y+ +++ ++L D         L +WLPVD+Y+GG EH
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLAD------EELLKQWLPVDIYVGGAEH  534

Query  538  AVGHLLYSRFWTHFLYDLGLLPTSEPFQRLFNQGMILGSDNR------------------  579
            AV HLLY+RFW   LYDLG++PT EPFQ+LFNQGMILG+  R                  
Sbjct  535  AVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGS  594

Query  580  ---------------KMSKSWGNVINPDDVIDTHGADALRLYEMFMGPLDASLPWSFDGL  624
                           KMSKS  NV+NPDDV++  GAD+LR+YEMFMGPLDAS++WS +GL
Sbjct  595  FFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGL  654

Query  625  DASLKWLNRCYRMINKVEFSNTNNHKLDYVYNDVVKKVTQMIKELKFNTAISQLMVLVNA  684
            ++S K L+R YR+I   E+++ N+  LD VYN+ VK VT+ + ++KFNTAI+QLMV+VNA
Sbjct  655  EGSRKFLDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNA  714

Query  685  IYKEELSTVYKPYIEGFVKMLSLFSPHLAEELWEKLGNRT-SVTLQTWPEFDETKIVKNT  743
              KE+   ++  Y  GFV++++ F+PHL+EELW+ L     S++   WP +DE+K+V N 
Sbjct  715  ANKED--KLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVEND  772

Query  744  VVIALQVNGKLRSTIEVEKGTDKEILIKLAQENENIIRFIKDHKNLKYIAVVDRIVNIVI  803
            V I +Q++GK+++ + V K+  +E L  +A  NE++   I +   +K IAV +++VNIVI
Sbjct  773  VEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

498) Caka_1388 in NC_014008


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  710 bits (2685),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 444/885 (51%), Positives = 591/885 (67%), Gaps = 92/885 (10%)

Query  8    YDFSAIEPKWQAFWSENKTYEAKDFEDQPTFYVLDMFPYPSGAGLHIGHPEGYTASDALK  67
            YD +AIEPKWQAFW++N T+ +     +P FY LDMFPYPSGAGLH+GHPEGYTA+D L 
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  68   RYKKAKGFNVLHPMGWDAFGLPTEQYAIKTGTHPATTTKQNVANFTAQLSQLGFAYDWNR  127
            R+K+A+G NVLHPMGWDAFGLP+EQYA+ TG +PA  T +N+ANF  Q++ LGF+YDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  128  EVNTTDPNYFKWTQWIFMQLFKKGLAYVDEKPVWFCPELGTVLANEEVLNTAEGPRSERG  187
            EVNTTDPNY+KWTQWIF +L+ KGLAY  E PV    ELGT +ANEEVL  +    SERG
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGT---SERG  180

Query  188  NFPVERRPIRQWVLRITEYAERLIAGLKDLDWPDSTKRLQENWIGRSEGGEITFDVSGHD  247
             +PV R+P+RQW+L+IT YAERL+ +L ++DWP+S K +Q NWIG+S G+++TF V + D
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  248  ARLTVFTTRPDTLYGATYMVIAPEHPLVAQITSEAQEAEVDAYIEKAKSKSDLERAELSK  307
              +TVFTTRPDTL+GATY V+APEH+LV  IT+  Q   V  Y  +A  KSDL R++L+K
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  308  EKSGVWTGATAINPVNGKEIPIWVADYVLMTYGTGAIMAVPAHDERDFDFAKAFDLDIVQ  367
            EK+GVWTG+ AINPVNGKE+P+W+ADYVL +YGTGAIMAVPAHDERD +FAK F+LDI+ 
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  368  VIEDDGSAEKDASGELASAYTGPGKLINSGEQSGNDSETAKNAIIEQLAADGRGKATVNF  427
            V+E++   E        +A+T  G  INS+   G D  +A   ++E L A+G G+  V +
Sbjct  361  VLEGGNVEE--------AAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTY  412

Query  428  KLRDWLFSRQRYWGEPFPIV-WVSEDDYAKADDSLKSVERPVSCQINGETRFalalpeae  486
            +LRDWLFSRQRYWGEP+PI+ W      A ++  L     P+   +  + R         
Sbjct  413  RLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESEL-----PLVLPVTKDIR---------  458

Query  487  lplnlpeVESYTPSPDGQSPLSKADSWLHVSVNPQTGETSTEAQDGWITGIRETNTMPQW  546
                        PS  G+SPL++   WL+V+            +DG + G RETNTMPQW
Sbjct  459  ------------PSGTGESPLANVTDWLEVT-----------REDG-VKGRRETNTMPQW  494

Query  547  AGSCWYYLRYIDPKNGTALIDPEKEQYWGTPDLYIGGAEHAVLHLLYARFWHQVLFDLGV  606
            AGS WYYLRYIDP N   L D E  + W   D+Y+GGAEHAVLHLLYARFWH+VL+DLGV
Sbjct  495  AGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGV  554

Query  607  VSDPEPFKKLFHQGIILG---------------------------------EDGEKMSKS  633
            V+  EPF+KLF+QG+ILG                                 +   KMSKS
Sbjct  555  VPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKS  614

Query  634  RGNVVNPETIIEGYGADALRCYLMFLGPLEAMKPWNTKGIEGIARFLRKVWRLVVDNDGQ  693
              NVVNP+ ++E YGAD+LR Y MF+GPL+A  +W+  G+EG  +FL +V RL+  ++  
Sbjct  615  LKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKE--  672

Query  694  ISTKIGASDALDPESDRVLHATIKKVSEDYESLGFNTAISQMMICVNQLAKAEALPKSVV  753
                   ++      D+V + T+K V+E+ + + FNTAI+Q+M+ VN   K + L     
Sbjct  673  ------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYA  726

Query  754  ESFLKLLAPLAPHIGEELWERLGNSGSIVE-AGWPECDESKLVQDTIKIVFQVNGKYRGD  812
             +F++L+AP+APH+GEELW+ L  SG  +    WP  DESKLV++ + IV Q++GK ++ 
Sbjct  727  KGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAK  786

Query  813  AELPADVSKEDAIAAAKANERVAGFIDGKDIKREIYVPGKIVNIV  857
              ++ D+S+E+    A ANE+V + I GKDI + I VP K+VNIV
Sbjct  787  LVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIV  831

499) leuS in NC_015977


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  709 bits (2682),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 434/843 (52%), Positives = 587/843 (70%), Gaps = 53/843 (6%)

Query  4    LYNHKVVEKKWQKVWDDNKAFAATDDYSKPKYYALVEFPYPSGQGLHVGHPRPYTALDIV  63
            +Y+H  +E KWQ  W DN +F +  D SKPK+YAL  FPYPSG GLHVGHP  YTA DI+
Sbjct  3    FYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDIL  62

Query  64   ARKRRMQGYNVLYPMGWDAFGLPTENYAIKNKIHPKIVTENNVKRFKEQLHSLGYSFDWD  123
            +R +R QG NVL PMGWDAFGLP+E+YA+    +P   T +N+  FK Q+++LG+S+DWD
Sbjct  63   SRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWD  122

Query  124  REINTTDPSYYKWTQWIFLKLFKAGLAYKKEMPINWCTSCKVGLANEEVV-NGVCERCGA  182
            RE+NTTDP+YYKWTQWIF KL+  GLAY  E+P+NW      ++ANEEV+ +G  ER G 
Sbjct  123  REVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGY  182

Query  183  PVVRKVKSEWMLKITDYAEKLIEGLDHVDYIERVKVSQKNWIGKSQGAEVDFSIKGKEDK  242
            PVVRK   +WMLKIT YAE+L+E+L++VD  E +K  Q+NWIGKS GA+V F +K+ +  
Sbjct  183  PVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LRVYTTRCDTLFGVTYMVVSPEHPIIDKYKDELKNWDAIAAYRDEAAKKSDFERAELAKE  302
            + V+TTR DTLFG TY V++PEH+++D      +  +A+A Y+ +A+ KSD+ R++LAKE
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQA-EAVADYKRQASLKSDLARTDLAKE  301

Query  303  KTGVQIEGLTAINPVNGKEIPIWISDYVLMSYGTGAIMAVPAHDERDWEFAKKFNLPLIQ  362
            KTGV   +  AINPVNGKE+P+WI+DYVL SYGTGAIMAVPAHDERDWEFAK+FNL +I 
Sbjct  302  KTGVWTGSY-AINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  363  VVAKNGEEVDINAAAFTDVATGVLINSDFLNGLEVKDAKAKMIAFLEEKKIGTAKTNYKL  422
            V+    E  +++ AAFT+   G+ INSDFL+GL+   A AKM+  LE   +G  +  Y+L
Sbjct  361  VL----EGGNVEEAAFTE--DGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRL  414

Query  423  RDWVFSRQRYWGEPIPIVHCDKCGYVPIDESELPLMLPEVESYMPTDNGESPLAAMTDWV  482
            RDW+FSRQRYWGEPIPI+H +     ++ ESELPL+LP      P++ GESPLA +TDW+
Sbjct  415  RDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWL  474

Query  483  NTTCPCCGGPAKRETDTMPQWAGSSWYFLRYTDPHNDEALASKEALKYWMPVDWYNGGME  542
            + T    G  ++RET+TMPQWAGSSWY+LRY DPHN E LA  E LK W+PVD Y GG E
Sbjct  475  EVTRE-DGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAE  533

Query  543  HTTLHLLYSRFWHKFLYDQGVVPCPEPYQKRTSHGMILG---------------------  581
            H+ LHLLY+RFWHK LYD GVVP  EP+QK  ++GMILG                     
Sbjct  534  HAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDG  593

Query  582  ------------ENGEKMSKSRGNVVNPDDIVREYGADTLRTYEMFIGAFDLSASWSEDG  629
                        +   KMSKS  NVVNPDD+V +YGADTLR YEMF+G++D S +WSE+G
Sbjct  594  SFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEG  653

Query  630  VKGCRRFLERIWKLQDIMTNEEGYSSDLETKMHQTIKKVSSDYENLKYNTAIAAMMALLN  689
            + G R+FL+R+ +L       E  S+ L+   ++T+K V+ + +++K+NTAIA +M ++N
Sbjct  654  LEGSRKFLDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVN  713

Query  690  DFTKKGSITKGEYKTLLILLNPVAPHITEELWQIIGGSG----YVYEQTWPEYEEAKTVE  745
               K + +  +  K ++ L+ P APH+ EELWQ + +SG    YV    WP Y+E+K VE
Sbjct  714  AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYV---PWPSYDESKLVE  770

Query  746  NTVEIAVQINGKTKGTLAIGRDDAKEDV--IAKAKESIADKLTG-NIVKEIYVPGRIVNI  802
            N VEI VQI+GK K+ L +++D ++E++  +A A+E +   ++G +I+K I VP ++VNI
Sbjct  771  NDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNI  830

Query  803  VMK  805
            V+K
Sbjct  831  VIK  833

500) leuS in NC_008095


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  708 bits (2676),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 428/860 (50%), Positives = 602/860 (70%), Gaps = 71/860 (8%)

Query  8    YDPANIEPLWQARWEEQRIFEARRHPGKPKAYILDMFPYPSGAGLHVGHPEGYTATDIVS  67
            YD + IEP WQA W +++ F +  +++KPK Y LDMFPYPSGAGLHVGHPEGYTATDI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  68   RYLRMRGYDVLHPMGWDAFGLPAEQHALETGTHPADTTAKNVATFKRQLKSLGFSYDWSR  127
            R+ R +G +VLHPMGWDAFGLPAEQ A++TG +PA+ TA N+A FKRQ+++LGFSYDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  128  ELSTTDPEYVRWTQWLFLKLFDRGLAYQAELPVNWCAALGTVLANEEVI-DGKSERGSHP  186
            E++TTDP+Y +WTQW+F KL+++GLAY+AE+PVNW   LGT +ANEEV+ DG SERG+ P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  187  VVRLPLRQWTLRITAYADRLAEDLSGLDWPET-REKQLHWIGRSEGAEVDFAIEGSADRL  245
            VVR P+RQW L+ITAYA+RL EDL  +DWPE+ ++ Q +WIG+S GA+V F + ++   +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  246  RIFTTRPDTLFGATYMVVAPEHPLLERFATAERRAEVLAYREATASRSELDRTALTKAKT  305
             +FTTRPDTLFGATY V+APEH+L++ ++T+++   V  Y+  ++ +S+L RT L+K KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  306  GVFTGSYALHPLTGARLPIWVADFVLGSYGTGAIMSVPGHDARDFEFARAFGLPVVEVVS  365
            GV TGSYA++P+ G  +P+W+AD+VL+SYGTGAIM+VP+HD RD EFA+ F L ++ V+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  366  VDGALNETGTWTEAFVGDGVAVRSRFLDGLRTPEAKAAMLAHLEREGLGARRVQYRLRDW  425
             +G ++E+     AF  DG+ + S FLDGL  + A A M+  LE EG+G   V YRLRDW
Sbjct  364  -GGNVEEA-----AFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDW  417

Query  426  VFSRQRYWGEPIPIYFPVELAEGSSDPRIHPHTIRYDQPLPVSEDELPVRLPELEDFKPS  485
            +FSRQRYWGEPIPI   ++  +G+S               +V+E ELP+ LP   D++PS
Sbjct  418  LFSRQRYWGEPIPI---IHWEDGTST--------------AVPESELPLVLPVTKDIRPS  460

Query  486  EDPAGPLARALDWRFFQRD----GKWYARETNTMPQWAGSCWYYLRFIDPKNTQAIFSQQ  541
                +PLA   DW    R+    G+   RETNTMPQWAGS WYYLR+IDP NT+ +  ++
Sbjct  461  GTGESPLANVTDWLEVTREDGVKGR---RETNTMPQWAGSSWYYLRYIDPHNTEKLADEE  517

Query  542  AYDAWMPVDLYVGGSEHAVLHLLYARFWHKVLFDCGLVTHAEPFKKLVHQGMILG-----  596
                W+PVD+YVGG+EHAVLHLLYARFWHKVL+D G+V   EPF+KL +QGMILG     
Sbjct  518  LLKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRD  577

Query  597  ----------------------------ENNEKMSKSRGNVVNPDDIVRQFGADALRMYE  628
                                        +   KMSKS  NVVNPDD+V Q+GAD+LR+YE
Sbjct  578  SRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYE  637

Query  629  MFMGPLEAVKPWQTNGVIGVRRFLDRVWNMLAFVTEDAGGAPAELTEDARRLLHKTVKKV  688
            MFMGPL+A  +W  +G+ G R+FLDRV  +++   E +   ++ L     ++ + TVK V
Sbjct  638  MFMGPLDASIAWSEEGLEGSRKFLDRVYRLIT-TKEITEENSGALD----KVYNETVKAV  692

Query  689  GEDIEALRFNTAVSAMMILANALAELPRVPLEAARVFARILSPFAPHLSEELWHRWGAS-  747
             E+++ ++FNTA++ +M++ NA     ++  + A+ F ++++PFAPHL+EELW+   AS 
Sbjct  693  TEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASG  752

Query  748  ESISLQPWPEYDPALTVDELVEMAIQVNGKVRGKLRLKRDATEAEAREAVHREPELIPHL  807
            ESIS  PWP YD +  V++ VE+ +Q++GKV++KL + +D +  E +E    +  + +++
Sbjct  753  ESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEI  812

Query  808  AGKTERRFVYVPGRIINIVV  827
            AGK   + + VP +++NIV+
Sbjct  813  AGKDIIKVIAVPNKLVNIVI  832

501) lueS in NC_005027


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  706 bits (2671),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 461/953 (49%), Positives = 619/953 (65%), Gaps = 123/953 (12%)

Query  1    MVRYNPNEIEPRWQAYWDEHHTFATPEKVGKKKRYVLDMFPYPSGDGLHVGHPEGYTATD  60
            M  Y+   IEP+WQA+W ++HTF T    +K K Y LDMFPYPSG GLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   IVSRFARARGESVLHPMGFDAFGLPAEEHAIKTGEHPRVQTQRNIDNFTRQLKMLGFSYD  120
            I+SRF RA+G++VLHPMG DAFGLPAE+ A+ TG++P   T  NI NF RQ++ LGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WDRVLATTDEEYFRWTQWIFGVLYDTWFDHDQQKGRPISELPIPAEVTAEGELEIEQYRD  180
            WDR + TTD +Y++WTQWIF  LY+                                   
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYE-----------------------------------  145

Query  181  SKRLAYLDDALVNWCPKLGTVLANEEVV-DGKSEVGGHPVKRIPLRQWMLRITDYAERLL  239
             K LAY  +  VNW   LGT +ANEEV+ DG SE GG PV R P+RQWML+IT YAERLL
Sbjct  146  -KGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLL  204

Query  240  DGLDDLDWPTGIKKLQSDWIGRSTGGEVDFYLQRGAAGDDTGPFVAFKRARESEGFPTDP  299
            ++L+++DWP +IK +Q +WIG+STG++V F                  + ++++      
Sbjct  205  EDLEEVDWPESIKDMQRNWIGKSTGANVTF------------------KVKDTD------  240

Query  300  GKDCLRVYTTRPDTLFGATYMVVAPEHPLIDVLVKPEQKDEVDAYREKASFKSDRERTDG  359
             KD + V+TTRPDTLFGATY V+APEH+L+D +  ++Q + V  Y+ +AS+KSD  RTD 
Sbjct  241  -KD-FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDL  298

Query  360  DRAKTGVFTGSYAINPADGRSIPIWVADYVLAGYGTGAIMAVPAHDERDFEFAVAFDLPV  419
             + KTGV TGSYAINP +G+ +P+W+ADYVLA+YGTGAIMAVPAHDERD EFA  F+L +
Sbjct  299  AKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDI  358

Query  420  IPVVDPPADHKQREEILAGKACFAAEGVAINSGEYDGKTTAEVKAALTAELAKQGLACEA  479
            IPV++               A F+ +G+ INS+  DG   A   A +   L  +G++ E 
Sbjct  359  IPVLEGGN---------VEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNEN  409

Query  480  VNYKLRDWLFSRQRFWGEPFPVLHEIDSEGNATGVRRLVPDDQLPVTLPELADFKPHGRP  539
            V Y+LRDWLFSRQR+WGEP+P++H  D+ + A      VP+ +LP+ LP   D++P G  
Sbjct  410  VTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTA------VPESELPLVLPVTKDIRPSGTG  463

Query  540  EPPLAKADDDWL-IVELDGKRYRRETNTMPQWAGSCWYYLRYIDPKNSDALIDPQKEKDW  598
            E+PLA+  D WL +   DG + RRETNTMPQWAGS WYYLRYIDP N++ L D +  K+W
Sbjct  464  ESPLANVTD-WLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQW  522

Query  599  MPVDLYVGGAEHAVLHLLYSRFWHKVLFDRGHVTCPEPFGKLVNQGMILGEVEFTSFVDP  658
            +PVD+YVGGAEHAVLHLLY+RFWHKVL+D G V   EPF KL NQGMILG    TS+ D+
Sbjct  523  LPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILG----TSYRDS  578

Query  659  SGKHVSTKDVKKDAEGNRVHKATGEQVEIVSLTEEQVVKKGEGFVLASDASIKVDSRAFK  718
             G  V+T  V K  +G+  H  TGE++E  +                            K
Sbjct  579  RGALVATDKVEK-RDGSFFHVETGEELEQAPA---------------------------K  610

Query  719  MSKSRGNVVNPDSVVRDYGADSLRLYEMFMGPLEATKPWAMNGVGGVRSFLDRVWRMIID  778
            MSKS  NVVNPD VV +YGAD+LR+YEMFMGPL+A+ +W+ +G+ G R FLDRV R+I  
Sbjct  611  MSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLI--  668

Query  779  EPEDELKVSDAVVDTACDEEQLRVLHQTIRKVTEDNEAMSFNTAIAKMMEFTNHFTRCET  838
                    +  + +   +  + +V ++T++ VTE+ + M FNTAIA++M F N   + + 
Sbjct  669  -------TTKEITEENSGALD-KVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  839  RPREAMESFLILLAPYAPHMCEELWKHL-GHNESISLQPWPKWDEAALVQSSIEIPVQIN  897
               +   +F+ L+AP+APH+ EELW+ L +  ESIS  PWP  DE+ LV++ +EI VQI+
Sbjct  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK  780

Query  898  GKVKAKISLSPDAKPNEMGEAALADPAVQNAIGDKKVVKTIAVPGRMVNLVVK  950
            GKVKAK+ ++ D   +E+ E ALA+  VQ  I++K ++K IAVP ++VN+V+K
Sbjct  781  GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

502) Amuc_1654 in NC_010655


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  701 bits (2650),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 459/894 (52%), Positives = 602/894 (68%), Gaps = 108/894 (12%)

Query  8    YPFDVFEPKWQQIWDERKTFKVNNPGEEGFDASKPKYYVLDMFPYPSGAGLHVGHPEGYT  67
            Y    +EPKWQ +W +  TFK       G DASKPK+Y LDMFPYPSGAGLHVGHPEGYT
Sbjct  4    YDHTAIEPKWQAFWADNHTFKT------GTDASKPKFYALDMFPYPSGAGLHVGHPEGYT  57

Query  68   ATDIVARFKRMNGFNVLHPMGWDSFGLPAEQYAIKTGQHPSVTTFRNIDNFRRQLKMLGF  127
            ATDI++RFKR +G NVLHPMGWD+FGLPAEQYA+ TG++P+  T  NI NF+RQ++ LGF
Sbjct  58   ATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGF  117

Query  128  SYDWDREIATTDHEYVRWTQWIFLQLYNSYYNKELKKARPVSELEEQGLSREEIDQRRLA  187
            SYDWDRE+ TTD +Y +WTQWIF +LY                            ++ LA
Sbjct  118  SYDWDREVNTTDPNYYKWTQWIFTKLY----------------------------EKGLA  149

Query  188  YVAEAAVNWSPDLGTVLANEEV---EEWKSKGHRVERRPLRQWMLRITDYAERLIDELEP  244
            Y AE +VNW  +LGT +ANEEV         G  V R+P+RQWML+IT YAERL+++LE 
Sbjct  150  YEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDLEE  209

Query  245  LDWPESIKLLQRNWIGKSEGAEVDFTL--DGETITVYTTRPDTLFGATYMVLSPEHPLVD  302
            +DWPESIK +QRNWIGKS GA+V F +   +  +TV+TTRPDTLFGATY VL+PEH+LVD
Sbjct  210  VDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHALVD  269

Query  303  TVTTPEQKHAVEQYRAQCASKSDLERTDLSKEKTGVFTGAYAVNPVNGKQIPVWIADYVL  362
            ++TT++Q +AV +Y+ Q + KSDL RTDL+KEKTGV TG+YA+NPVNGK++PVWIADYVL
Sbjct  270  AITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAINPVNGKEMPVWIADYVL  329

Query  363  MGYGTGAIMAVPAHDERDFAFAQVFGLPILQVVQPPSEDTDWRGFCGYEGSSVNSGFLTG  422
             +YGTGAIMAVPAHDERD  FA+ F L I+ V++  + +    +F   +G  +NS+FL G
Sbjct  330  ASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEA--AFTE-DGLHINSDFLDG  386

Query  423  LPTPEAKEKMILWLEENGKGRRKVNYKLRDWLFSRQRYWGEPFPIV-WEDGRHRALPESE  481
            L  + A  KM+ WLE +G G  +V Y+LRDWLFSRQRYWGEP+PI+ WEDG   A+PESE
Sbjct  387  LDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESE  446

Query  482  LPVLQPDLDDFAPTGDPRGPLVKAAEWIAYTP----TAHRETNTMPQWAGSCWYYLRYLD  537
            LP++ P   D+ P+G   +PL + ++W+  T      ++RETNTMPQWAGS WYYLRY+D
Sbjct  447  LPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYID  506

Query  538  PANTERFVSREAEQYWMGSAGSPGGVDLYVGGTEHAVLHLLYARFWHKVLFDLGYLSTNE  597
            P NTE++   E  + W+        VD+YVGG+EHAVLHLLYARFWHKVL+DLG ++T+E
Sbjct  507  PHNTEKLADEELLKQWL-------PVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKE  559

Query  598  PFQKLVNQGLILG---------------------------------EDGQKMSKSRGNVV  624
            PFQKL NQG+ILG                                 +   KMSKS  NVV
Sbjct  560  PFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVV  619

Query  625  NPDDIVREYGADSLRLYEMFMGPLKDVKPWATKGVEGISRFLARVWRVAFRENQEGEWEI  684
            NPDD+V +YGAD+LR+YEMFMGPL    +W+  G+EG  +FL RV R+           I
Sbjct  620  NPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRL-----------I  668

Query  685  NSKLVENAPEAGVLAVRKELHKTIKKVTEDINGMSFNTAIAKMMECTNAMTSADVVDVQD  744
             +K + +   +   A+ K  + T+K VTE+++ M FNTAIA++M   NA    D +   D
Sbjct  669  TTKEITEENSG---ALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKL-FSD  724

Query  745  YD-AFLTLLNPFAPHLTEEIHSRLQTAFPALAQTQLCQKSWPEWEEALLEENTVPMVIQV  803
            Y  +F+ L+ PFAPHL EE+   L +     +   +   +WP  +E+ L EN V +V+Q+
Sbjct  725  YAKGFVQLIAPFAPHLGEELWQALTA-----SGESISYVPWPSYDESKLVENDVEIVVQI  779

Query  804  NGKLRDKLEVPKDISREELEKQALASAKVKTFLDGVTVRKVIVVPGRLVNIVAN  857
            +GK++ KL V+KD+SREEL+  ALA+ KV++ + G  + KVI VP +LVNIV +
Sbjct  780  KGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

503) ROI_24380 in NC_021040


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  699 bits (2642),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 427/843 (51%), Positives = 584/843 (70%), Gaps = 53/843 (6%)

Query  4    LYNHKVVEKKWQKVWDDNKAFAATDDYSKPKYYALVEFPYPSGQGLHVGHPRPYTALDIV  63
            +Y+H  +E KWQ  W DN +F +  D SKPK+YAL  FPYPSG GLHVGHP  YTA DI+
Sbjct  3    FYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDIL  62

Query  64   ARKRRMQGYNVLYPMGWDAFGLPTENYAIKNKIHPKIVTENNVKRFKEQLHSLGYSFDWD  123
            +R +R QG NVL PMGWDAFGLP+E+YA+    +P   T +N+  FK Q+++LG+S+DWD
Sbjct  63   SRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWD  122

Query  124  REINTTDPSYYKWTQWIFLKLFKAGLAYKKEMPINWCTSCKVGLANEEVV-NGVCERCGA  182
            RE+NTTDP+YYKWTQWIF KL+  GLAY  E+P+NW      ++ANEEV+ +G  ER G 
Sbjct  123  REVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGY  182

Query  183  PVVRKVKSEWMLKITDYAEKLLEGLNDVDYIERVKVSQKNWIGKSQGAEVDFAIAGKEDK  242
            PVVRK   +WMLKIT YAE+LLE+L++VD  E +K  Q+NWIGKS GA+V F + + +  
Sbjct  183  PVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LRVYTTRCDTLFGATYMVVSPEHPIIDKYKDELKNWDAIAAYREEAAKKSDFERSELAKD  302
            + V+TTR DTLFGATY V++PEH+++D      +  +A+A Y+ +A+ KSD+ R++LAK+
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQA-EAVADYKRQASLKSDLARTDLAKE  301

Query  303  KTGVEIDGLMAVNPVTGKEIPIWISDYVLMSYGTGAIMAVPAHDERDWEFAKKFNIPMVQ  362
            KTGV   G  A+NPV GKE+P+WI+DYVL SYGTGAIMAVPAHDERDWEFAK+FN+ ++ 
Sbjct  302  KTGV-WTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  363  VVAKNGEEVDINEAAFTDVATGVLINSEFLNGLEVKDAKAKMIAFLEEKGIGTAKTNYKL  422
            V+    E  +++EAAFT+   G+ INS+FL+GL+   A AKM+  LE  G+G  +  Y+L
Sbjct  361  VL----EGGNVEEAAFTE--DGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRL  414

Query  423  RDWVFSRQRYWGEPIPIVHCDKCGYVPIDESELPLMLPEVESYMPTDNGESPLAAMTDWV  482
            RDW+FSRQRYWGEPIPI+H +     ++ ESELPL+LP      P++ GESPLA +TDW+
Sbjct  415  RDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWL  474

Query  483  NTTCPCCGGPAKRETDTMPQWAGSSWYFLRYTDPHNDEALASPEALKYWMPVDWYNGGME  542
            + T    G  ++RET+TMPQWAGSSWY+LRY DPHN E LA  E LK W+PVD Y GG E
Sbjct  475  EVTRE-DGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAE  533

Query  543  HTTLHLLYSRFWHKFLYDEKVVPCPEPYQKRTSHGMILG---------------------  581
            H+ LHLLY+RFWHK LYD  VVP  EP+QK  ++GMILG                     
Sbjct  534  HAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDG  593

Query  582  ------------ENGEKMSKSRGNVVNPDDIVREYGADTLRTYEMFIGAFDLSASWSEDG  629
                        +   KMSKS  NVVNPDD+V +YGADTLR YEMF+G++D S +WSE+G
Sbjct  594  SFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEG  653

Query  630  VKGCRRFLERVWKLQDIMTEETGYSKELETKMHQTIKKVSSDYENLKYNTAIAAMMALIN  689
            + G R+FL+RV +L          S  L+   ++T+K V+ + +++K+NTAIA +M ++N
Sbjct  654  LEGSRKFLDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVN  713

Query  690  EFYKKNAVTKGEYETLLILLNPVAPHITEELWQIIGGTG----YVYQQKWPEFDEAKTVE  745
               K + +  +    ++ L+ P APH+ EELWQ + ++G    YV    WP +DE+K VE
Sbjct  714  AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYV---PWPSYDESKLVE  770

Query  746  NTVEIAVQINGKTKGTLAIGRNDAKDDV--IAKAKESIADKLTG-NIVKEIYVPGRIVNI  802
            N VEI VQI+GK K+ L ++++ +++++  +A A+E +   ++G +I+K I VP ++VNI
Sbjct  771  NDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNI  830

Query  803  VMK  805
            V+K
Sbjct  831  VIK  833

504) RO1_13160 in NC_021012


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  699 bits (2642),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 427/843 (51%), Positives = 584/843 (70%), Gaps = 53/843 (6%)

Query  4    LYNHKVVEKKWQKVWDDNKAFAATDDYSKPKYYALVEFPYPSGQGLHVGHPRPYTALDIV  63
            +Y+H  +E KWQ  W DN +F +  D SKPK+YAL  FPYPSG GLHVGHP  YTA DI+
Sbjct  3    FYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDIL  62

Query  64   ARKRRMQGYNVLYPMGWDAFGLPTENYAIKNKIHPKIVTENNVKRFKEQLHSLGYSFDWD  123
            +R +R QG NVL PMGWDAFGLP+E+YA+    +P   T +N+  FK Q+++LG+S+DWD
Sbjct  63   SRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWD  122

Query  124  REINTTDPSYYKWTQWIFLKLFKAGLAYKKEMPINWCTSCKVGLANEEVV-NGVCERCGA  182
            RE+NTTDP+YYKWTQWIF KL+  GLAY  E+P+NW      ++ANEEV+ +G  ER G 
Sbjct  123  REVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGY  182

Query  183  PVVRKVKSEWMLKITDYAEKLLEGLNDVDYIERVKVSQKNWIGKSQGAEVDFAIAGKEDK  242
            PVVRK   +WMLKIT YAE+LLE+L++VD  E +K  Q+NWIGKS GA+V F + + +  
Sbjct  183  PVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LRVYTTRCDTLFGATYMVVSPEHPIIDKYKDELKNWDAIAAYREEAAKKSDFERSELAKD  302
            + V+TTR DTLFGATY V++PEH+++D      +  +A+A Y+ +A+ KSD+ R++LAK+
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQA-EAVADYKRQASLKSDLARTDLAKE  301

Query  303  KTGVEIDGLMAVNPVTGKEIPIWISDYVLMSYGTGAIMAVPAHDERDWEFAKKFNIPMVQ  362
            KTGV   G  A+NPV GKE+P+WI+DYVL SYGTGAIMAVPAHDERDWEFAK+FN+ ++ 
Sbjct  302  KTGV-WTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  363  VVAKNGEEVDINEAAFTDVATGVLINSEFLNGLEVKDAKAKMIAFLEEKGIGTAKTNYKL  422
            V+    E  +++EAAFT+   G+ INS+FL+GL+   A AKM+  LE  G+G  +  Y+L
Sbjct  361  VL----EGGNVEEAAFTE--DGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRL  414

Query  423  RDWVFSRQRYWGEPIPIVHCDKCGYVPIDESELPLMLPEVESYMPTDNGESPLAAMTDWV  482
            RDW+FSRQRYWGEPIPI+H +     ++ ESELPL+LP      P++ GESPLA +TDW+
Sbjct  415  RDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWL  474

Query  483  NTTCPCCGGPAKRETDTMPQWAGSSWYFLRYTDPHNDEALASPEALKYWMPVDWYNGGME  542
            + T    G  ++RET+TMPQWAGSSWY+LRY DPHN E LA  E LK W+PVD Y GG E
Sbjct  475  EVTRE-DGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAE  533

Query  543  HTTLHLLYSRFWHKFLYDEKVVPCPEPYQKRTSHGMILG---------------------  581
            H+ LHLLY+RFWHK LYD  VVP  EP+QK  ++GMILG                     
Sbjct  534  HAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDG  593

Query  582  ------------ENGEKMSKSRGNVVNPDDIVREYGADTLRTYEMFIGAFDLSASWSEDG  629
                        +   KMSKS  NVVNPDD+V +YGADTLR YEMF+G++D S +WSE+G
Sbjct  594  SFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEG  653

Query  630  VKGCRRFLERVWKLQDIMTEETGYSKELETKMHQTIKKVSSDYENLKYNTAIAAMMALIN  689
            + G R+FL+RV +L          S  L+   ++T+K V+ + +++K+NTAIA +M ++N
Sbjct  654  LEGSRKFLDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVN  713

Query  690  EFYKKNAVTKGEYETLLILLNPVAPHITEELWQIIGGTG----YVYQQKWPEFDEAKTVE  745
               K + +  +    ++ L+ P APH+ EELWQ + ++G    YV    WP +DE+K VE
Sbjct  714  AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYV---PWPSYDESKLVE  770

Query  746  NTVEIAVQINGKTKGTLAIGRNDAKDDV--IAKAKESIADKLTG-NIVKEIYVPGRIVNI  802
            N VEI VQI+GK K+ L ++++ +++++  +A A+E +   ++G +I+K I VP ++VNI
Sbjct  771  NDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNI  830

Query  803  VMK  805
            V+K
Sbjct  831  VIK  833

505) leuS in NC_017434


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  699 bits (2642),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 414/834 (50%), Positives = 601/834 (73%), Gaps = 22/834 (2%)

Query  3    YDPGLIEEKWQKFWENEQVFKAEEDETKTKYYVLDMFPYPSGAGLHVGHLIGYTATDIVA  62
            YD   IE KWQ FW +++ FK+  D +K K+Y LDMFPYPSGAGLHVGH  GYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRAQGFSVLHPMGWDSFGLPAEQYAIRTGTHPRETTEKNIANFKKQLTAMGFSYDESR  122
            R+KRAQG +VLHPMGWD+FGLPAEQYA+ TG +P E T  NIANFK+Q+ A+GFSYD  R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EFATSDPEYYKWTQKLFLILYEKGLAYMADMAVNYCPELGTVLSNEEI-ENGFSVDGGYP  181
            E  T+DP+YYKWTQ +F  LYEKGLAY A+++VN   ELGT ++NEE+  +G S  GGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRMLRQWVLRITAFADQLLEGLDELDWPESVKQLQKNWIGKSSGASVNFATEHGVIE-  240
            V R+ +RQW+L+ITA+A++LLE+L+E+DWPES+K++Q+NWIGKS+GA+V F   +   + 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  -VFTTRPDTLIGVSFLALAPEHPLVDLLTSDEQKAVVAQYIKETQSKSERDRISEMKTKS  299
             VFTTRPDTL+G ++  LAPEH+LVD +T+ +Q   VA+Y +++  KS+  R    K K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  300  GVFTGSYAKHPVTHKLIPIWIADYVLIGFGSGAVMGVPAHDERDLLFAEQFNLPVVSVLN  359
            GV TGSYA +PV  K +P+WIADYVL ++G+GA+M+VPAHDERD  FA QFNL +++VL+
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  360  KEGVCINSCCE-GFH-----LDGLSGEEAKQYVINFLEENHLGAAKIAYKLRDWLFSRQR  413
               V   +  E G+H     LDGL    A   +++ LE + +G  +++Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  414  YWGEPIPIIHFEDGSCRPLRDYELPLLPPEIQDYRPEGVGQGPLAKVREWVQVFDTETQR  473
            YWGEPIPIIH EDG+  ++ + ELPL+ P  +D RP G G++PLA+V +W++V   +  +
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  474  AGKRETHTMPQWAGSCWYYLRFCDAHNSAAPWAKEKEQYWMPVDLYIGGAEHAVLHLLYA  533
             G+RET+TMPQWAGS WYYLR+ D+HN+      E  + W+PVD+Y+GGAEHAVLHLLYA
Sbjct  484  -GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  534  RFWHQVFYEAGIVSTPEPFKKLVNQGLVLATSYRIPGKGYIYPE-IAKEENGKWVAPSGE  592
            RFWH+V+Y+ G+V+T EPF+KL NQG++L+TSYR +  + +  + + K + +     +GE
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  593  ELDVRQEKMSKSKLNGVDPQILIDEFGADAVRMYAMFSGPLDKNKLWSNQGVAGCRRFLN  652
            EL+    KMSKS  N V+P+ +++++GAD++R+Y MF GPLD +  WS++G+ G R+FL+
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  653  RFYEMVSSDRVKEDNNFEGLSLAHKLVQRVTDAIEKLSLNTIPSSFMEFINDFVK----L  708
            R Y ++++  + E+N+     + +  V+ VT+ ++++ +NT  + +M F+N   K    +
Sbjct  663  RVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLF  722

Query  709  AVYPKSAVEMAVRALAPIAPHISEELW-VLLGNSPGVQKSGWPSVLPEYLEGQTVTIVVQ  767
            + Y+K+ V++    +AP+APH++EELW  L +++ ++    WPS     L  + V IVVQ
Sbjct  723  SDYAKGFVQL----IAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQ  778

Query  768  VNGKLRARLDIMKDASKEEV--LALARESASKYLEGCEVKKAIFVPARLVNFVV  819
            ++GK++A+L + KD S+EE+  +ALA E     + G ++ K I VP +LVN+V+
Sbjct  779  IKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

506) leuS in NC_017436


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  699 bits (2642),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 414/834 (50%), Positives = 601/834 (73%), Gaps = 22/834 (2%)

Query  3    YDPGLIEEKWQKFWENEQVFKAEEDETKTKYYVLDMFPYPSGAGLHVGHLIGYTATDIVA  62
            YD   IE KWQ FW +++ FK+  D +K K+Y LDMFPYPSGAGLHVGH  GYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRAQGFSVLHPMGWDSFGLPAEQYAIRTGTHPRETTEKNIANFKKQLTAMGFSYDESR  122
            R+KRAQG +VLHPMGWD+FGLPAEQYA+ TG +P E T  NIANFK+Q+ A+GFSYD  R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EFATSDPEYYKWTQKLFLILYEKGLAYMADMAVNYCPELGTVLSNEEI-ENGFSVDGGYP  181
            E  T+DP+YYKWTQ +F  LYEKGLAY A+++VN   ELGT ++NEE+  +G S  GGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRMLRQWVLRITAFADQLLEGLDELDWPESVKQLQKNWIGKSSGASVNFATEHGVIE-  240
            V R+ +RQW+L+ITA+A++LLE+L+E+DWPES+K++Q+NWIGKS+GA+V F   +   + 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  -VFTTRPDTLIGVSFLALAPEHPLVDLLTSDEQKAVVAQYIKETQSKSERDRISEMKTKS  299
             VFTTRPDTL+G ++  LAPEH+LVD +T+ +Q   VA+Y +++  KS+  R    K K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  300  GVFTGSYAKHPVTHKLIPIWIADYVLIGFGSGAVMGVPAHDERDLLFAEQFNLPVVSVLN  359
            GV TGSYA +PV  K +P+WIADYVL ++G+GA+M+VPAHDERD  FA QFNL +++VL+
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  360  KEGVCINSCCE-GFH-----LDGLSGEEAKQYVINFLEENHLGAAKIAYKLRDWLFSRQR  413
               V   +  E G+H     LDGL    A   +++ LE + +G  +++Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  414  YWGEPIPIIHFEDGSCRPLRDYELPLLPPEIQDYRPEGVGQGPLAKVREWVQVFDTETQR  473
            YWGEPIPIIH EDG+  ++ + ELPL+ P  +D RP G G++PLA+V +W++V   +  +
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  474  AGKRETHTMPQWAGSCWYYLRFCDAHNSAAPWAKEKEQYWMPVDLYIGGAEHAVLHLLYA  533
             G+RET+TMPQWAGS WYYLR+ D+HN+      E  + W+PVD+Y+GGAEHAVLHLLYA
Sbjct  484  -GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  534  RFWHQVFYEAGIVSTPEPFKKLVNQGLVLATSYRIPGKGYIYPE-IAKEENGKWVAPSGE  592
            RFWH+V+Y+ G+V+T EPF+KL NQG++L+TSYR +  + +  + + K + +     +GE
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  593  ELDVRQEKMSKSKLNGVDPQILIDEFGADAVRMYAMFSGPLDKNKLWSNQGVAGCRRFLN  652
            EL+    KMSKS  N V+P+ +++++GAD++R+Y MF GPLD +  WS++G+ G R+FL+
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  653  RFYEMVSSDRVKEDNNFEGLSLAHKLVQRVTDAIEKLSLNTIPSSFMEFINDFVK----L  708
            R Y ++++  + E+N+     + +  V+ VT+ ++++ +NT  + +M F+N   K    +
Sbjct  663  RVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLF  722

Query  709  AVYPKSAVEMAVRALAPIAPHISEELW-VLLGNSPGVQKSGWPSVLPEYLEGQTVTIVVQ  767
            + Y+K+ V++    +AP+APH++EELW  L +++ ++    WPS     L  + V IVVQ
Sbjct  723  SDYAKGFVQL----IAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQ  778

Query  768  VNGKLRARLDIMKDASKEEV--LALARESASKYLEGCEVKKAIFVPARLVNFVV  819
            ++GK++A+L + KD S+EE+  +ALA E     + G ++ K I VP +LVN+V+
Sbjct  779  IKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

507) SOTOND1_00217 in NC_020967


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  699 bits (2642),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 414/834 (50%), Positives = 601/834 (73%), Gaps = 22/834 (2%)

Query  3    YDPGLIEEKWQKFWENEQVFKAEEDETKTKYYVLDMFPYPSGAGLHVGHLIGYTATDIVA  62
            YD   IE KWQ FW +++ FK+  D +K K+Y LDMFPYPSGAGLHVGH  GYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRAQGFSVLHPMGWDSFGLPAEQYAIRTGTHPRETTEKNIANFKKQLTAMGFSYDESR  122
            R+KRAQG +VLHPMGWD+FGLPAEQYA+ TG +P E T  NIANFK+Q+ A+GFSYD  R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EFATSDPEYYKWTQKLFLILYEKGLAYMADMAVNYCPELGTVLSNEEI-ENGFSVDGGYP  181
            E  T+DP+YYKWTQ +F  LYEKGLAY A+++VN   ELGT ++NEE+  +G S  GGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRMLRQWVLRITAFADQLLEGLDELDWPESVKQLQKNWIGKSSGASVNFATEHGVIE-  240
            V R+ +RQW+L+ITA+A++LLE+L+E+DWPES+K++Q+NWIGKS+GA+V F   +   + 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  -VFTTRPDTLIGVSFLALAPEHPLVDLLTSDEQKAVVAQYIKETQSKSERDRISEMKTKS  299
             VFTTRPDTL+G ++  LAPEH+LVD +T+ +Q   VA+Y +++  KS+  R    K K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  300  GVFTGSYAKHPVTHKLIPIWIADYVLMGFGSGAVMGVPAHDERDLLFAEQFNLPVVSVLN  359
            GV TGSYA +PV  K +P+WIADYVL ++G+GA+M+VPAHDERD  FA QFNL +++VL+
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  360  KEGVCINSCCE-GFH-----LDGLSGEEAKQYVINFLEENHLGAAKIAYKLRDWLFSRQR  413
               V   +  E G+H     LDGL    A   +++ LE + +G  +++Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  414  YWGEPIPIIHFEDGSCRPLRDYELPLLPPEIQDYRPEGVGQGPLAKVREWVQVFDTETQR  473
            YWGEPIPIIH EDG+  ++ + ELPL+ P  +D RP G G++PLA+V +W++V   +  +
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  474  AGKRETHTMPQWAGSCWYYLRFCDAHNSAAPWAKEKEQYWMPVDLYIGGAEHAVLHLLYA  533
             G+RET+TMPQWAGS WYYLR+ D+HN+      E  + W+PVD+Y+GGAEHAVLHLLYA
Sbjct  484  -GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  534  RFWHQVFYEAGIVSTPEPFKKLVNQGLVLATSYRIPGKGYIYPE-IAKEENGKWVAPSGE  592
            RFWH+V+Y+ G+V+T EPF+KL NQG++L+TSYR +  + +  + + K + +     +GE
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  593  ELDVRQEKMSKSKLNGVDPQILIDEFGADAVRMYAMFSGPLDKNKLWSNQGVAGCRRFLN  652
            EL+    KMSKS  N V+P+ +++++GAD++R+Y MF GPLD +  WS++G+ G R+FL+
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  653  RFYEMVSSDRVKEDNNFEGLSLAHKLVQRVTDAIEKLSLNTIPSSFMEFINDFVK----L  708
            R Y ++++  + E+N+     + +  V+ VT+ ++++ +NT  + +M F+N   K    +
Sbjct  663  RVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLF  722

Query  709  AVYPKSAVEMAVRALAPIAPHISEELW-VLLGNSPGVQKSGWPSVLPEYLEGQTVTIVVQ  767
            + Y+K+ V++    +AP+APH++EELW  L +++ ++    WPS     L  + V IVVQ
Sbjct  723  SDYAKGFVQL----IAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQ  778

Query  768  VNGKLRARLDIMKDASKEEV--LALARESASKYLEGCEVKKAIFVPARLVNFVV  819
            ++GK++A+L + KD S+EE+  +ALA E     + G ++ K I VP +LVN+V+
Sbjct  779  IKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

508) SOTOND5_00216 in NC_020943


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  699 bits (2642),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 414/834 (50%), Positives = 601/834 (73%), Gaps = 22/834 (2%)

Query  3    YDPGLIEEKWQKFWENEQVFKAEEDETKTKYYVLDMFPYPSGAGLHVGHLIGYTATDIVA  62
            YD   IE KWQ FW +++ FK+  D +K K+Y LDMFPYPSGAGLHVGH  GYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRAQGFSVLHPMGWDSFGLPAEQYAIRTGTHPRETTEKNIANFKKQLTAMGFSYDESR  122
            R+KRAQG +VLHPMGWD+FGLPAEQYA+ TG +P E T  NIANFK+Q+ A+GFSYD  R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EFATSDPEYYKWTQKLFLILYEKGLAYMADMAVNYCPELGTVLSNEEI-ENGFSVDGGYP  181
            E  T+DP+YYKWTQ +F  LYEKGLAY A+++VN   ELGT ++NEE+  +G S  GGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRMLRQWVLRITAFADQLLEGLDELDWPESVKQLQKNWIGKSSGASVNFATEHGVIE-  240
            V R+ +RQW+L+ITA+A++LLE+L+E+DWPES+K++Q+NWIGKS+GA+V F   +   + 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  -VFTTRPDTLIGVSFLALAPEHPLVDLLTSDEQKAVVAQYIKETQSKSERDRISEMKTKS  299
             VFTTRPDTL+G ++  LAPEH+LVD +T+ +Q   VA+Y +++  KS+  R    K K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  300  GVFTGSYAKHPVTHKLIPIWIADYVLMGFGSGAVMGVPAHDERDLLFAEQFNLPVVSVLN  359
            GV TGSYA +PV  K +P+WIADYVL ++G+GA+M+VPAHDERD  FA QFNL +++VL+
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  360  KEGVCINSCCE-GFH-----LDGLSGEEAKQYVINFLEENHLGAAKIAYKLRDWLFSRQR  413
               V   +  E G+H     LDGL    A   +++ LE + +G  +++Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  414  YWGEPIPIIHFEDGSCRPLRDYELPLLPPEIQDYRPEGVGQGPLAKVREWVQVFDTETQR  473
            YWGEPIPIIH EDG+  ++ + ELPL+ P  +D RP G G++PLA+V +W++V   +  +
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  474  AGKRETHTMPQWAGSCWYYLRFCDAHNSAAPWAKEKEQYWMPVDLYIGGAEHAVLHLLYA  533
             G+RET+TMPQWAGS WYYLR+ D+HN+      E  + W+PVD+Y+GGAEHAVLHLLYA
Sbjct  484  -GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  534  RFWHQVFYEAGIVSTPEPFKKLVNQGLVLATSYRIPGKGYIYPE-IAKEENGKWVAPSGE  592
            RFWH+V+Y+ G+V+T EPF+KL NQG++L+TSYR +  + +  + + K + +     +GE
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  593  ELDVRQEKMSKSKLNGVDPQILIDEFGADAVRMYAMFSGPLDKNKLWSNQGVAGCRRFLN  652
            EL+    KMSKS  N V+P+ +++++GAD++R+Y MF GPLD +  WS++G+ G R+FL+
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  653  RFYEMVSSDRVKEDNNFEGLSLAHKLVQRVTDAIEKLSLNTIPSSFMEFINDFVK----L  708
            R Y ++++  + E+N+     + +  V+ VT+ ++++ +NT  + +M F+N   K    +
Sbjct  663  RVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLF  722

Query  709  AVYPKSAVEMAVRALAPIAPHISEELW-VLLGNSPGVQKSGWPSVLPEYLEGQTVTIVVQ  767
            + Y+K+ V++    +AP+APH++EELW  L +++ ++    WPS     L  + V IVVQ
Sbjct  723  SDYAKGFVQL----IAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQ  778

Query  768  VNGKLRARLDIMKDASKEEV--LALARESASKYLEGCEVKKAIFVPARLVNFVV  819
            ++GK++A+L + KD S+EE+  +ALA E     + G ++ K I VP +LVN+V+
Sbjct  779  IKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

509) SOTOND6_00216 in NC_020968


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  699 bits (2642),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 414/834 (50%), Positives = 601/834 (73%), Gaps = 22/834 (2%)

Query  3    YDPGLIEEKWQKFWENEQVFKAEEDETKTKYYVLDMFPYPSGAGLHVGHLIGYTATDIVA  62
            YD   IE KWQ FW +++ FK+  D +K K+Y LDMFPYPSGAGLHVGH  GYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRAQGFSVLHPMGWDSFGLPAEQYAIRTGTHPRETTEKNIANFKKQLTAMGFSYDESR  122
            R+KRAQG +VLHPMGWD+FGLPAEQYA+ TG +P E T  NIANFK+Q+ A+GFSYD  R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EFATSDPEYYKWTQKLFLILYEKGLAYMADMAVNYCPELGTVLSNEEI-ENGFSVDGGYP  181
            E  T+DP+YYKWTQ +F  LYEKGLAY A+++VN   ELGT ++NEE+  +G S  GGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRMLRQWVLRITAFADQLLEGLDELDWPESVKQLQKNWIGKSSGASVNFATEHGVIE-  240
            V R+ +RQW+L+ITA+A++LLE+L+E+DWPES+K++Q+NWIGKS+GA+V F   +   + 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  -VFTTRPDTLIGVSFLALAPEHPLVDLLTSDEQKAVVAQYIKETQSKSERDRISEMKTKS  299
             VFTTRPDTL+G ++  LAPEH+LVD +T+ +Q   VA+Y +++  KS+  R    K K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  300  GVFTGSYAKHPVTHKLIPIWIADYVLMGFGSGAVMGVPAHDERDLLFAEQFNLPVVSVLN  359
            GV TGSYA +PV  K +P+WIADYVL ++G+GA+M+VPAHDERD  FA QFNL +++VL+
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  360  KEGVCINSCCE-GFH-----LDGLSGEEAKQYVINFLEENHLGAAKIAYKLRDWLFSRQR  413
               V   +  E G+H     LDGL    A   +++ LE + +G  +++Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  414  YWGEPIPIIHFEDGSCRPLRDYELPLLPPEIQDYRPEGVGQGPLAKVREWVQVFDTETQR  473
            YWGEPIPIIH EDG+  ++ + ELPL+ P  +D RP G G++PLA+V +W++V   +  +
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  474  AGKRETHTMPQWAGSCWYYLRFCDAHNSAAPWAKEKEQYWMPVDLYIGGAEHAVLHLLYA  533
             G+RET+TMPQWAGS WYYLR+ D+HN+      E  + W+PVD+Y+GGAEHAVLHLLYA
Sbjct  484  -GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  534  RFWHQVFYEAGIVSTPEPFKKLVNQGLVLATSYRIPGKGYIYPE-IAKEENGKWVAPSGE  592
            RFWH+V+Y+ G+V+T EPF+KL NQG++L+TSYR +  + +  + + K + +     +GE
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  593  ELDVRQEKMSKSKLNGVDPQILIDEFGADAVRMYAMFSGPLDKNKLWSNQGVAGCRRFLN  652
            EL+    KMSKS  N V+P+ +++++GAD++R+Y MF GPLD +  WS++G+ G R+FL+
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  653  RFYEMVSSDRVKEDNNFEGLSLAHKLVQRVTDAIEKLSLNTIPSSFMEFINDFVK----L  708
            R Y ++++  + E+N+     + +  V+ VT+ ++++ +NT  + +M F+N   K    +
Sbjct  663  RVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLF  722

Query  709  AVYPKSAVEMAVRALAPIAPHISEELW-VLLGNSPGVQKSGWPSVLPEYLEGQTVTIVVQ  767
            + Y+K+ V++    +AP+APH++EELW  L +++ ++    WPS     L  + V IVVQ
Sbjct  723  SDYAKGFVQL----IAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQ  778

Query  768  VNGKLRARLDIMKDASKEEV--LALARESASKYLEGCEVKKAIFVPARLVNFVV  819
            ++GK++A+L + KD S+EE+  +ALA E     + G ++ K I VP +LVN+V+
Sbjct  779  IKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

510) leuS in NC_000117


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  699 bits (2642),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 414/834 (50%), Positives = 601/834 (73%), Gaps = 22/834 (2%)

Query  3    YDPGLIEEKWQKFWENEQVFKAEEDETKTKYYVLDMFPYPSGAGLHVGHLIGYTATDIVA  62
            YD   IE KWQ FW +++ FK+  D +K K+Y LDMFPYPSGAGLHVGH  GYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRAQGFSVLHPMGWDSFGLPAEQYAIRTGTHPRETTEKNIANFKKQLTAMGFSYDESR  122
            R+KRAQG +VLHPMGWD+FGLPAEQYA+ TG +P E T  NIANFK+Q+ A+GFSYD  R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EFATSDPEYYKWTQKLFLILYEKGLAYMADMAVNYCPELGTVLSNEEI-ENGFSVDGGYP  181
            E  T+DP+YYKWTQ +F  LYEKGLAY A+++VN   ELGT ++NEE+  +G S  GGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRMLRQWVLRITAFADQLLEGLDELDWPESVKQLQKNWIGKSSGASVNFATEHGVIE-  240
            V R+ +RQW+L+ITA+A++LLE+L+E+DWPES+K++Q+NWIGKS+GA+V F   +   + 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  -VFTTRPDTLIGVSFLALAPEHPLVDLLTSDEQKAVVAQYIKETQSKSERDRISEMKTKS  299
             VFTTRPDTL+G ++  LAPEH+LVD +T+ +Q   VA+Y +++  KS+  R    K K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  300  GVFTGSYAKHPVTHKLIPIWIADYVLIGFGSGAVMGVPAHDERDLLFAEQFNLPVVSVLN  359
            GV TGSYA +PV  K +P+WIADYVL ++G+GA+M+VPAHDERD  FA QFNL +++VL+
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  360  KEGVCINSCCE-GFH-----LDGLSGEEAKQYVINFLEENHLGAAKIAYKLRDWLFSRQR  413
               V   +  E G+H     LDGL    A   +++ LE + +G  +++Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  414  YWGEPIPIIHFEDGSCRPLRDYELPLLPPEIQDYRPEGVGQGPLAKVREWVQVFDTETQR  473
            YWGEPIPIIH EDG+  ++ + ELPL+ P  +D RP G G++PLA+V +W++V   +  +
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  474  AGKRETHTMPQWAGSCWYYLRFCDAHNSAAPWAKEKEQYWMPVDLYIGGAEHAVLHLLYA  533
             G+RET+TMPQWAGS WYYLR+ D+HN+      E  + W+PVD+Y+GGAEHAVLHLLYA
Sbjct  484  -GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  534  RFWHQVFYEAGIVSTPEPFKKLVNQGLVLATSYRIPGKGYIYPE-IAKEENGKWVAPSGE  592
            RFWH+V+Y+ G+V+T EPF+KL NQG++L+TSYR +  + +  + + K + +     +GE
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  593  ELDVRQEKMSKSKLNGVDPQILIDEFGADAVRMYAMFSGPLDKNKLWSNQGVAGCRRFLN  652
            EL+    KMSKS  N V+P+ +++++GAD++R+Y MF GPLD +  WS++G+ G R+FL+
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  653  RFYEMVSSDRVKEDNNFEGLSLAHKLVQRVTDAIEKLSLNTIPSSFMEFINDFVK----L  708
            R Y ++++  + E+N+     + +  V+ VT+ ++++ +NT  + +M F+N   K    +
Sbjct  663  RVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLF  722

Query  709  AVYPKSAVEMAVRALAPIAPHISEELW-VLLGNSPGVQKSGWPSVLPEYLEGQTVTIVVQ  767
            + Y+K+ V++    +AP+APH++EELW  L +++ ++    WPS     L  + V IVVQ
Sbjct  723  SDYAKGFVQL----IAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQ  778

Query  768  VNGKLRARLDIMKDASKEEV--LALARESASKYLEGCEVKKAIFVPARLVNFVV  819
            ++GK++A+L + KD S+EE+  +ALA E     + G ++ K I VP +LVN+V+
Sbjct  779  IKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

511) leuS in NC_017431


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  699 bits (2642),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 414/834 (50%), Positives = 601/834 (73%), Gaps = 22/834 (2%)

Query  3    YDPGLIEEKWQKFWENEQVFKAEEDETKTKYYVLDMFPYPSGAGLHVGHLIGYTATDIVA  62
            YD   IE KWQ FW +++ FK+  D +K K+Y LDMFPYPSGAGLHVGH  GYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRAQGFSVLHPMGWDSFGLPAEQYAIRTGTHPRETTEKNIANFKKQLTAMGFSYDESR  122
            R+KRAQG +VLHPMGWD+FGLPAEQYA+ TG +P E T  NIANFK+Q+ A+GFSYD  R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EFATSDPEYYKWTQKLFLILYEKGLAYMADMAVNYCPELGTVLSNEEI-ENGFSVDGGYP  181
            E  T+DP+YYKWTQ +F  LYEKGLAY A+++VN   ELGT ++NEE+  +G S  GGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRMLRQWVLRITAFADQLLEGLDELDWPESVKQLQKNWIGKSSGASVNFATEHGVIE-  240
            V R+ +RQW+L+ITA+A++LLE+L+E+DWPES+K++Q+NWIGKS+GA+V F   +   + 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  -VFTTRPDTLIGVSFLALAPEHPLVDLLTSDEQKAVVAQYIKETQSKSERDRISEMKTKS  299
             VFTTRPDTL+G ++  LAPEH+LVD +T+ +Q   VA+Y +++  KS+  R    K K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  300  GVFTGSYAKHPVTHKLIPIWIADYVLMGFGSGAVMGVPAHDERDLLFAEQFNLPVVSVLN  359
            GV TGSYA +PV  K +P+WIADYVL ++G+GA+M+VPAHDERD  FA QFNL +++VL+
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  360  KEGVCINSCCE-GFH-----LDGLSGEEAKQYVINFLEENHLGAAKIAYKLRDWLFSRQR  413
               V   +  E G+H     LDGL    A   +++ LE + +G  +++Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  414  YWGEPIPIIHFEDGSCRPLRDYELPLLPPEIQDYRPEGVGQGPLAKVREWVQVFDTETQR  473
            YWGEPIPIIH EDG+  ++ + ELPL+ P  +D RP G G++PLA+V +W++V   +  +
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  474  AGKRETHTMPQWAGSCWYYLRFCDAHNSAAPWAKEKEQYWMPVDLYIGGAEHAVLHLLYA  533
             G+RET+TMPQWAGS WYYLR+ D+HN+      E  + W+PVD+Y+GGAEHAVLHLLYA
Sbjct  484  -GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  534  RFWHQVFYEAGIVSTPEPFKKLVNQGLVLATSYRIPGKGYIYPE-IAKEENGKWVAPSGE  592
            RFWH+V+Y+ G+V+T EPF+KL NQG++L+TSYR +  + +  + + K + +     +GE
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  593  ELDVRQEKMSKSKLNGVDPQILIDEFGADAVRMYAMFSGPLDKNKLWSNQGVAGCRRFLN  652
            EL+    KMSKS  N V+P+ +++++GAD++R+Y MF GPLD +  WS++G+ G R+FL+
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  653  RFYEMVSSDRVKEDNNFEGLSLAHKLVQRVTDAIEKLSLNTIPSSFMEFINDFVK----L  708
            R Y ++++  + E+N+     + +  V+ VT+ ++++ +NT  + +M F+N   K    +
Sbjct  663  RVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLF  722

Query  709  AVYPKSAVEMAVRALAPIAPHISEELW-VLLGNSPGVQKSGWPSVLPEYLEGQTVTIVVQ  767
            + Y+K+ V++    +AP+APH++EELW  L +++ ++    WPS     L  + V IVVQ
Sbjct  723  SDYAKGFVQL----IAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQ  778

Query  768  VNGKLRARLDIMKDASKEEV--LALARESASKYLEGCEVKKAIFVPARLVNFVV  819
            ++GK++A+L + KD S+EE+  +ALA E     + G ++ K I VP +LVN+V+
Sbjct  779  IKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

512) leuS in NC_017439


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  699 bits (2642),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 414/834 (50%), Positives = 601/834 (73%), Gaps = 22/834 (2%)

Query  3    YDPGLIEEKWQKFWENEQVFKAEEDETKTKYYVLDMFPYPSGAGLHVGHLIGYTATDIVA  62
            YD   IE KWQ FW +++ FK+  D +K K+Y LDMFPYPSGAGLHVGH  GYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRAQGFSVLHPMGWDSFGLPAEQYAIRTGTHPRETTEKNIANFKKQLTAMGFSYDESR  122
            R+KRAQG +VLHPMGWD+FGLPAEQYA+ TG +P E T  NIANFK+Q+ A+GFSYD  R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EFATSDPEYYKWTQKLFLILYEKGLAYMADMAVNYCPELGTVLSNEEI-ENGFSVDGGYP  181
            E  T+DP+YYKWTQ +F  LYEKGLAY A+++VN   ELGT ++NEE+  +G S  GGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRMLRQWVLRITAFADQLLEGLDELDWPESVKQLQKNWIGKSSGASVNFATEHGVIE-  240
            V R+ +RQW+L+ITA+A++LLE+L+E+DWPES+K++Q+NWIGKS+GA+V F   +   + 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  -VFTTRPDTLIGVSFLALAPEHPLVDLLTSDEQKAVVAQYIKETQSKSERDRISEMKTKS  299
             VFTTRPDTL+G ++  LAPEH+LVD +T+ +Q   VA+Y +++  KS+  R    K K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  300  GVFTGSYAKHPVTHKLIPIWIADYVLMGFGSGAVMGVPAHDERDLLFAEQFNLPVVSVLN  359
            GV TGSYA +PV  K +P+WIADYVL ++G+GA+M+VPAHDERD  FA QFNL +++VL+
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  360  KEGVCINSCCE-GFH-----LDGLSGEEAKQYVINFLEENHLGAAKIAYKLRDWLFSRQR  413
               V   +  E G+H     LDGL    A   +++ LE + +G  +++Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  414  YWGEPIPIIHFEDGSCRPLRDYELPLLPPEIQDYRPEGVGQGPLAKVREWVQVFDTETQR  473
            YWGEPIPIIH EDG+  ++ + ELPL+ P  +D RP G G++PLA+V +W++V   +  +
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  474  AGKRETHTMPQWAGSCWYYLRFCDAHNSAAPWAKEKEQYWMPVDLYIGGAEHAVLHLLYA  533
             G+RET+TMPQWAGS WYYLR+ D+HN+      E  + W+PVD+Y+GGAEHAVLHLLYA
Sbjct  484  -GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  534  RFWHQVFYEAGIVSTPEPFKKLVNQGLVLATSYRIPGKGYIYPE-IAKEENGKWVAPSGE  592
            RFWH+V+Y+ G+V+T EPF+KL NQG++L+TSYR +  + +  + + K + +     +GE
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  593  ELDVRQEKMSKSKLNGVDPQILIDEFGADAVRMYAMFSGPLDKNKLWSNQGVAGCRRFLN  652
            EL+    KMSKS  N V+P+ +++++GAD++R+Y MF GPLD +  WS++G+ G R+FL+
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  653  RFYEMVSSDRVKEDNNFEGLSLAHKLVQRVTDAIEKLSLNTIPSSFMEFINDFVK----L  708
            R Y ++++  + E+N+     + +  V+ VT+ ++++ +NT  + +M F+N   K    +
Sbjct  663  RVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLF  722

Query  709  AVYPKSAVEMAVRALAPIAPHISEELW-VLLGNSPGVQKSGWPSVLPEYLEGQTVTIVVQ  767
            + Y+K+ V++    +AP+APH++EELW  L +++ ++    WPS     L  + V IVVQ
Sbjct  723  SDYAKGFVQL----IAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQ  778

Query  768  VNGKLRARLDIMKDASKEEV--LALARESASKYLEGCEVKKAIFVPARLVNFVV  819
            ++GK++A+L + KD S+EE+  +ALA E     + G ++ K I VP +LVN+V+
Sbjct  779  IKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

513) BOUR_00219 in NC_020971


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  699 bits (2642),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 414/834 (50%), Positives = 601/834 (73%), Gaps = 22/834 (2%)

Query  3    YDPGLIEEKWQKFWENEQVFKAEEDETKTKYYVLDMFPYPSGAGLHVGHLIGYTATDIVA  62
            YD   IE KWQ FW +++ FK+  D +K K+Y LDMFPYPSGAGLHVGH  GYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRAQGFSVLHPMGWDSFGLPAEQYAIRTGTHPRETTEKNIANFKKQLTAMGFSYDESR  122
            R+KRAQG +VLHPMGWD+FGLPAEQYA+ TG +P E T  NIANFK+Q+ A+GFSYD  R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EFATSDPEYYKWTQKLFLILYEKGLAYMADMAVNYCPELGTVLSNEEI-ENGFSVDGGYP  181
            E  T+DP+YYKWTQ +F  LYEKGLAY A+++VN   ELGT ++NEE+  +G S  GGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRMLRQWVLRITAFADQLLEGLDELDWPESVKQLQKNWIGKSSGASVNFATEHGVIE-  240
            V R+ +RQW+L+ITA+A++LLE+L+E+DWPES+K++Q+NWIGKS+GA+V F   +   + 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  -VFTTRPDTLIGVSFLALAPEHPLVDLLTSDEQKAVVAQYIKETQSKSERDRISEMKTKS  299
             VFTTRPDTL+G ++  LAPEH+LVD +T+ +Q   VA+Y +++  KS+  R    K K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  300  GVFTGSYAKHPVTHKLIPIWIADYVLMGFGSGAVMGVPAHDERDLLFAEQFNLPVVSVLN  359
            GV TGSYA +PV  K +P+WIADYVL ++G+GA+M+VPAHDERD  FA QFNL +++VL+
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  360  KEGVCINSCCE-GFH-----LDGLSGEEAKQYVINFLEENHLGAAKIAYKLRDWLFSRQR  413
               V   +  E G+H     LDGL    A   +++ LE + +G  +++Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  414  YWGEPIPIIHFEDGSCRPLRDYELPLLPPEIQDYRPEGVGQGPLAKVREWVQVFDTETQR  473
            YWGEPIPIIH EDG+  ++ + ELPL+ P  +D RP G G++PLA+V +W++V   +  +
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  474  AGKRETHTMPQWAGSCWYYLRFCDAHNSAAPWAKEKEQYWMPVDLYIGGAEHAVLHLLYA  533
             G+RET+TMPQWAGS WYYLR+ D+HN+      E  + W+PVD+Y+GGAEHAVLHLLYA
Sbjct  484  -GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  534  RFWHQVFYEAGIVSTPEPFKKLVNQGLVLATSYRIPGKGYIYPE-IAKEENGKWVAPSGE  592
            RFWH+V+Y+ G+V+T EPF+KL NQG++L+TSYR +  + +  + + K + +     +GE
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  593  ELDVRQEKMSKSKLNGVDPQILIDEFGADAVRMYAMFSGPLDKNKLWSNQGVAGCRRFLN  652
            EL+    KMSKS  N V+P+ +++++GAD++R+Y MF GPLD +  WS++G+ G R+FL+
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  653  RFYEMVSSDRVKEDNNFEGLSLAHKLVQRVTDAIEKLSLNTIPSSFMEFINDFVK----L  708
            R Y ++++  + E+N+     + +  V+ VT+ ++++ +NT  + +M F+N   K    +
Sbjct  663  RVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLF  722

Query  709  AVYPKSAVEMAVRALAPIAPHISEELW-VLLGNSPGVQKSGWPSVLPEYLEGQTVTIVVQ  767
            + Y+K+ V++    +AP+APH++EELW  L +++ ++    WPS     L  + V IVVQ
Sbjct  723  SDYAKGFVQL----IAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQ  778

Query  768  VNGKLRARLDIMKDASKEEV--LALARESASKYLEGCEVKKAIFVPARLVNFVV  819
            ++GK++A+L + KD S+EE+  +ALA E     + G ++ K I VP +LVN+V+
Sbjct  779  IKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

514) SOTONE8_00221 in NC_020942


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  699 bits (2642),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 414/834 (50%), Positives = 601/834 (73%), Gaps = 22/834 (2%)

Query  3    YDPGLIEEKWQKFWENEQVFKAEEDETKTKYYVLDMFPYPSGAGLHVGHLIGYTATDIVA  62
            YD   IE KWQ FW +++ FK+  D +K K+Y LDMFPYPSGAGLHVGH  GYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRAQGFSVLHPMGWDSFGLPAEQYAIRTGTHPRETTEKNIANFKKQLTAMGFSYDESR  122
            R+KRAQG +VLHPMGWD+FGLPAEQYA+ TG +P E T  NIANFK+Q+ A+GFSYD  R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EFATSDPEYYKWTQKLFLILYEKGLAYMADMAVNYCPELGTVLSNEEI-ENGFSVDGGYP  181
            E  T+DP+YYKWTQ +F  LYEKGLAY A+++VN   ELGT ++NEE+  +G S  GGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRMLRQWVLRITAFADQLLEGLDELDWPESVKQLQKNWIGKSSGASVNFATEHGVIE-  240
            V R+ +RQW+L+ITA+A++LLE+L+E+DWPES+K++Q+NWIGKS+GA+V F   +   + 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  -VFTTRPDTLIGVSFLALAPEHPLVDLLTSDEQKAVVAQYIKETQSKSERDRISEMKTKS  299
             VFTTRPDTL+G ++  LAPEH+LVD +T+ +Q   VA+Y +++  KS+  R    K K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  300  GVFTGSYAKHPVTHKLIPIWIADYVLMGFGSGAVMGVPAHDERDLLFAEQFNLPVVSVLN  359
            GV TGSYA +PV  K +P+WIADYVL ++G+GA+M+VPAHDERD  FA QFNL +++VL+
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  360  KEGVCINSCCE-GFH-----LDGLSGEEAKQYVINFLEENHLGAAKIAYKLRDWLFSRQR  413
               V   +  E G+H     LDGL    A   +++ LE + +G  +++Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  414  YWGEPIPIIHFEDGSCRPLRDYELPLLPPEIQDYRPEGVGQGPLAKVREWVQVFDTETQR  473
            YWGEPIPIIH EDG+  ++ + ELPL+ P  +D RP G G++PLA+V +W++V   +  +
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  474  AGKRETHTMPQWAGSCWYYLRFCDAHNSAAPWAKEKEQYWMPVDLYIGGAEHAVLHLLYA  533
             G+RET+TMPQWAGS WYYLR+ D+HN+      E  + W+PVD+Y+GGAEHAVLHLLYA
Sbjct  484  -GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  534  RFWHQVFYEAGIVSTPEPFKKLVNQGLVLATSYRIPGKGYIYPE-IAKEENGKWVAPSGE  592
            RFWH+V+Y+ G+V+T EPF+KL NQG++L+TSYR +  + +  + + K + +     +GE
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  593  ELDVRQEKMSKSKLNGVDPQILIDEFGADAVRMYAMFSGPLDKNKLWSNQGVAGCRRFLN  652
            EL+    KMSKS  N V+P+ +++++GAD++R+Y MF GPLD +  WS++G+ G R+FL+
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  653  RFYEMVSSDRVKEDNNFEGLSLAHKLVQRVTDAIEKLSLNTIPSSFMEFINDFVK----L  708
            R Y ++++  + E+N+     + +  V+ VT+ ++++ +NT  + +M F+N   K    +
Sbjct  663  RVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLF  722

Query  709  AVYPKSAVEMAVRALAPIAPHISEELW-VLLGNSPGVQKSGWPSVLPEYLEGQTVTIVVQ  767
            + Y+K+ V++    +AP+APH++EELW  L +++ ++    WPS     L  + V IVVQ
Sbjct  723  SDYAKGFVQL----IAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQ  778

Query  768  VNGKLRARLDIMKDASKEEV--LALARESASKYLEGCEVKKAIFVPARLVNFVV  819
            ++GK++A+L + KD S+EE+  +ALA E     + G ++ K I VP +LVN+V+
Sbjct  779  IKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

515) leuS in NC_017952


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  699 bits (2642),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 414/834 (50%), Positives = 601/834 (73%), Gaps = 22/834 (2%)

Query  3    YDPGLIEEKWQKFWENEQVFKAEEDETKTKYYVLDMFPYPSGAGLHVGHLIGYTATDIVA  62
            YD   IE KWQ FW +++ FK+  D +K K+Y LDMFPYPSGAGLHVGH  GYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRAQGFSVLHPMGWDSFGLPAEQYAIRTGTHPRETTEKNIANFKKQLTAMGFSYDESR  122
            R+KRAQG +VLHPMGWD+FGLPAEQYA+ TG +P E T  NIANFK+Q+ A+GFSYD  R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EFATSDPEYYKWTQKLFLILYEKGLAYMADMAVNYCPELGTVLSNEEI-ENGFSVDGGYP  181
            E  T+DP+YYKWTQ +F  LYEKGLAY A+++VN   ELGT ++NEE+  +G S  GGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRMLRQWVLRITAFADQLLEGLDELDWPESVKQLQKNWIGKSSGASVNFATEHGVIE-  240
            V R+ +RQW+L+ITA+A++LLE+L+E+DWPES+K++Q+NWIGKS+GA+V F   +   + 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  -VFTTRPDTLIGVSFLALAPEHPLVDLLTSDEQKAVVAQYIKETQSKSERDRISEMKTKS  299
             VFTTRPDTL+G ++  LAPEH+LVD +T+ +Q   VA+Y +++  KS+  R    K K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  300  GVFTGSYAKHPVTHKLIPIWIADYVLMGFGSGAVMGVPAHDERDLLFAEQFNLPVVSVLN  359
            GV TGSYA +PV  K +P+WIADYVL ++G+GA+M+VPAHDERD  FA QFNL +++VL+
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  360  KEGVCINSCCE-GFH-----LDGLSGEEAKQYVINFLEENHLGAAKIAYKLRDWLFSRQR  413
               V   +  E G+H     LDGL    A   +++ LE + +G  +++Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  414  YWGEPIPIIHFEDGSCRPLRDYELPLLPPEIQDYRPEGVGQGPLAKVREWVQVFDTETQR  473
            YWGEPIPIIH EDG+  ++ + ELPL+ P  +D RP G G++PLA+V +W++V   +  +
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  474  AGKRETHTMPQWAGSCWYYLRFCDAHNSAAPWAKEKEQYWMPVDLYIGGAEHAVLHLLYA  533
             G+RET+TMPQWAGS WYYLR+ D+HN+      E  + W+PVD+Y+GGAEHAVLHLLYA
Sbjct  484  -GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  534  RFWHQVFYEAGIVSTPEPFKKLVNQGLVLATSYRIPGKGYIYPE-IAKEENGKWVAPSGE  592
            RFWH+V+Y+ G+V+T EPF+KL NQG++L+TSYR +  + +  + + K + +     +GE
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  593  ELDVRQEKMSKSKLNGVDPQILIDEFGADAVRMYAMFSGPLDKNKLWSNQGVAGCRRFLN  652
            EL+    KMSKS  N V+P+ +++++GAD++R+Y MF GPLD +  WS++G+ G R+FL+
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  653  RFYEMVSSDRVKEDNNFEGLSLAHKLVQRVTDAIEKLSLNTIPSSFMEFINDFVK----L  708
            R Y ++++  + E+N+     + +  V+ VT+ ++++ +NT  + +M F+N   K    +
Sbjct  663  RVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLF  722

Query  709  AVYPKSAVEMAVRALAPIAPHISEELW-VLLGNSPGVQKSGWPSVLPEYLEGQTVTIVVQ  767
            + Y+K+ V++    +AP+APH++EELW  L +++ ++    WPS     L  + V IVVQ
Sbjct  723  SDYAKGFVQL----IAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQ  778

Query  768  VNGKLRARLDIMKDASKEEV--LALARESASKYLEGCEVKKAIFVPARLVNFVV  819
            ++GK++A+L + KD S+EE+  +ALA E     + G ++ K I VP +LVN+V+
Sbjct  779  IKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

516) leuS in NC_017951


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  699 bits (2642),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 414/834 (50%), Positives = 601/834 (73%), Gaps = 22/834 (2%)

Query  3    YDPGLIEEKWQKFWENEQVFKAEEDETKTKYYVLDMFPYPSGAGLHVGHLIGYTATDIVA  62
            YD   IE KWQ FW +++ FK+  D +K K+Y LDMFPYPSGAGLHVGH  GYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRAQGFSVLHPMGWDSFGLPAEQYAIRTGTHPRETTEKNIANFKKQLTAMGFSYDESR  122
            R+KRAQG +VLHPMGWD+FGLPAEQYA+ TG +P E T  NIANFK+Q+ A+GFSYD  R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EFATSDPEYYKWTQKLFLILYEKGLAYMADMAVNYCPELGTVLSNEEI-ENGFSVDGGYP  181
            E  T+DP+YYKWTQ +F  LYEKGLAY A+++VN   ELGT ++NEE+  +G S  GGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRMLRQWVLRITAFADQLLEGLDELDWPESVKQLQKNWIGKSSGASVNFATEHGVIE-  240
            V R+ +RQW+L+ITA+A++LLE+L+E+DWPES+K++Q+NWIGKS+GA+V F   +   + 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  -VFTTRPDTLIGVSFLALAPEHPLVDLLTSDEQKAVVAQYIKETQSKSERDRISEMKTKS  299
             VFTTRPDTL+G ++  LAPEH+LVD +T+ +Q   VA+Y +++  KS+  R    K K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  300  GVFTGSYAKHPVTHKLIPIWIADYVLMGFGSGAVMGVPAHDERDLLFAEQFNLPVVSVLN  359
            GV TGSYA +PV  K +P+WIADYVL ++G+GA+M+VPAHDERD  FA QFNL +++VL+
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  360  KEGVCINSCCE-GFH-----LDGLSGEEAKQYVINFLEENHLGAAKIAYKLRDWLFSRQR  413
               V   +  E G+H     LDGL    A   +++ LE + +G  +++Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  414  YWGEPIPIIHFEDGSCRPLRDYELPLLPPEIQDYRPEGVGQGPLAKVREWVQVFDTETQR  473
            YWGEPIPIIH EDG+  ++ + ELPL+ P  +D RP G G++PLA+V +W++V   +  +
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  474  AGKRETHTMPQWAGSCWYYLRFCDAHNSAAPWAKEKEQYWMPVDLYIGGAEHAVLHLLYA  533
             G+RET+TMPQWAGS WYYLR+ D+HN+      E  + W+PVD+Y+GGAEHAVLHLLYA
Sbjct  484  -GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  534  RFWHQVFYEAGIVSTPEPFKKLVNQGLVLATSYRIPGKGYIYPE-IAKEENGKWVAPSGE  592
            RFWH+V+Y+ G+V+T EPF+KL NQG++L+TSYR +  + +  + + K + +     +GE
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  593  ELDVRQEKMSKSKLNGVDPQILIDEFGADAVRMYAMFSGPLDKNKLWSNQGVAGCRRFLN  652
            EL+    KMSKS  N V+P+ +++++GAD++R+Y MF GPLD +  WS++G+ G R+FL+
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  653  RFYEMVSSDRVKEDNNFEGLSLAHKLVQRVTDAIEKLSLNTIPSSFMEFINDFVK----L  708
            R Y ++++  + E+N+     + +  V+ VT+ ++++ +NT  + +M F+N   K    +
Sbjct  663  RVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLF  722

Query  709  AVYPKSAVEMAVRALAPIAPHISEELW-VLLGNSPGVQKSGWPSVLPEYLEGQTVTIVVQ  767
            + Y+K+ V++    +AP+APH++EELW  L +++ ++    WPS     L  + V IVVQ
Sbjct  723  SDYAKGFVQL----IAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQ  778

Query  768  VNGKLRARLDIMKDASKEEV--LALARESASKYLEGCEVKKAIFVPARLVNFVV  819
            ++GK++A+L + KD S+EE+  +ALA E     + G ++ K I VP +LVN+V+
Sbjct  779  IKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

517) leuS in NC_017953


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  699 bits (2642),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 414/834 (50%), Positives = 601/834 (73%), Gaps = 22/834 (2%)

Query  3    YDPGLIEEKWQKFWENEQVFKAEEDETKTKYYVLDMFPYPSGAGLHVGHLIGYTATDIVA  62
            YD   IE KWQ FW +++ FK+  D +K K+Y LDMFPYPSGAGLHVGH  GYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRAQGFSVLHPMGWDSFGLPAEQYAIRTGTHPRETTEKNIANFKKQLTAMGFSYDESR  122
            R+KRAQG +VLHPMGWD+FGLPAEQYA+ TG +P E T  NIANFK+Q+ A+GFSYD  R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EFATSDPEYYKWTQKLFLILYEKGLAYMADMAVNYCPELGTVLSNEEI-ENGFSVDGGYP  181
            E  T+DP+YYKWTQ +F  LYEKGLAY A+++VN   ELGT ++NEE+  +G S  GGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRMLRQWVLRITAFADQLLEGLDELDWPESVKQLQKNWIGKSSGASVNFATEHGVIE-  240
            V R+ +RQW+L+ITA+A++LLE+L+E+DWPES+K++Q+NWIGKS+GA+V F   +   + 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  -VFTTRPDTLIGVSFLALAPEHPLVDLLTSDEQKAVVAQYIKETQSKSERDRISEMKTKS  299
             VFTTRPDTL+G ++  LAPEH+LVD +T+ +Q   VA+Y +++  KS+  R    K K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  300  GVFTGSYAKHPVTHKLIPIWIADYVLMGFGSGAVMGVPAHDERDLLFAEQFNLPVVSVLN  359
            GV TGSYA +PV  K +P+WIADYVL ++G+GA+M+VPAHDERD  FA QFNL +++VL+
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  360  KEGVCINSCCE-GFH-----LDGLSGEEAKQYVINFLEENHLGAAKIAYKLRDWLFSRQR  413
               V   +  E G+H     LDGL    A   +++ LE + +G  +++Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  414  YWGEPIPIIHFEDGSCRPLRDYELPLLPPEIQDYRPEGVGQGPLAKVREWVQVFDTETQR  473
            YWGEPIPIIH EDG+  ++ + ELPL+ P  +D RP G G++PLA+V +W++V   +  +
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  474  AGKRETHTMPQWAGSCWYYLRFCDAHNSAAPWAKEKEQYWMPVDLYIGGAEHAVLHLLYA  533
             G+RET+TMPQWAGS WYYLR+ D+HN+      E  + W+PVD+Y+GGAEHAVLHLLYA
Sbjct  484  -GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  534  RFWHQVFYEAGIVSTPEPFKKLVNQGLVLATSYRIPGKGYIYPE-IAKEENGKWVAPSGE  592
            RFWH+V+Y+ G+V+T EPF+KL NQG++L+TSYR +  + +  + + K + +     +GE
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  593  ELDVRQEKMSKSKLNGVDPQILIDEFGADAVRMYAMFSGPLDKNKLWSNQGVAGCRRFLN  652
            EL+    KMSKS  N V+P+ +++++GAD++R+Y MF GPLD +  WS++G+ G R+FL+
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  653  RFYEMVSSDRVKEDNNFEGLSLAHKLVQRVTDAIEKLSLNTIPSSFMEFINDFVK----L  708
            R Y ++++  + E+N+     + +  V+ VT+ ++++ +NT  + +M F+N   K    +
Sbjct  663  RVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLF  722

Query  709  AVYPKSAVEMAVRALAPIAPHISEELW-VLLGNSPGVQKSGWPSVLPEYLEGQTVTIVVQ  767
            + Y+K+ V++    +AP+APH++EELW  L +++ ++    WPS     L  + V IVVQ
Sbjct  723  SDYAKGFVQL----IAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQ  778

Query  768  VNGKLRARLDIMKDASKEEV--LALARESASKYLEGCEVKKAIFVPARLVNFVV  819
            ++GK++A+L + KD S+EE+  +ALA E     + G ++ K I VP +LVN+V+
Sbjct  779  IKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

518) leuS in NC_017440


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  699 bits (2642),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 414/834 (50%), Positives = 601/834 (73%), Gaps = 22/834 (2%)

Query  3    YDPGLIEEKWQKFWENEQVFKAEEDETKTKYYVLDMFPYPSGAGLHVGHLIGYTATDIVA  62
            YD   IE KWQ FW +++ FK+  D +K K+Y LDMFPYPSGAGLHVGH  GYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRAQGFSVLHPMGWDSFGLPAEQYAIRTGTHPRETTEKNIANFKKQLTAMGFSYDESR  122
            R+KRAQG +VLHPMGWD+FGLPAEQYA+ TG +P E T  NIANFK+Q+ A+GFSYD  R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EFATSDPEYYKWTQKLFLILYEKGLAYMADMAVNYCPELGTVLSNEEI-ENGFSVDGGYP  181
            E  T+DP+YYKWTQ +F  LYEKGLAY A+++VN   ELGT ++NEE+  +G S  GGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRMLRQWVLRITAFADQLLEGLDELDWPESVKQLQKNWIGKSSGASVNFATEHGVIE-  240
            V R+ +RQW+L+ITA+A++LLE+L+E+DWPES+K++Q+NWIGKS+GA+V F   +   + 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  -VFTTRPDTLIGVSFLALAPEHPLVDLLTSDEQKAVVAQYIKETQSKSERDRISEMKTKS  299
             VFTTRPDTL+G ++  LAPEH+LVD +T+ +Q   VA+Y +++  KS+  R    K K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  300  GVFTGSYAKHPVTHKLIPIWIADYVLMGFGSGAVMGVPAHDERDLLFAEQFNLPVVSVLN  359
            GV TGSYA +PV  K +P+WIADYVL ++G+GA+M+VPAHDERD  FA QFNL +++VL+
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  360  KEGVCINSCCE-GFH-----LDGLSGEEAKQYVINFLEENHLGAAKIAYKLRDWLFSRQR  413
               V   +  E G+H     LDGL    A   +++ LE + +G  +++Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  414  YWGEPIPIIHFEDGSCRPLRDYELPLLPPEIQDYRPEGVGQGPLAKVREWVQVFDTETQR  473
            YWGEPIPIIH EDG+  ++ + ELPL+ P  +D RP G G++PLA+V +W++V   +  +
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  474  AGKRETHTMPQWAGSCWYYLRFCDAHNSAAPWAKEKEQYWMPVDLYIGGAEHAVLHLLYA  533
             G+RET+TMPQWAGS WYYLR+ D+HN+      E  + W+PVD+Y+GGAEHAVLHLLYA
Sbjct  484  -GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  534  RFWHQVFYEAGIVSTPEPFKKLVNQGLVLATSYRIPGKGYIYPE-IAKEENGKWVAPSGE  592
            RFWH+V+Y+ G+V+T EPF+KL NQG++L+TSYR +  + +  + + K + +     +GE
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  593  ELDVRQEKMSKSKLNGVDPQILIDEFGADAVRMYAMFSGPLDKNKLWSNQGVAGCRRFLN  652
            EL+    KMSKS  N V+P+ +++++GAD++R+Y MF GPLD +  WS++G+ G R+FL+
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  653  RFYEMVSSDRVKEDNNFEGLSLAHKLVQRVTDAIEKLSLNTIPSSFMEFINDFVK----L  708
            R Y ++++  + E+N+     + +  V+ VT+ ++++ +NT  + +M F+N   K    +
Sbjct  663  RVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLF  722

Query  709  AVYPKSAVEMAVRALAPIAPHISEELW-VLLGNSPGVQKSGWPSVLPEYLEGQTVTIVVQ  767
            + Y+K+ V++    +AP+APH++EELW  L +++ ++    WPS     L  + V IVVQ
Sbjct  723  SDYAKGFVQL----IAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQ  778

Query  768  VNGKLRARLDIMKDASKEEV--LALARESASKYLEGCEVKKAIFVPARLVNFVV  819
            ++GK++A+L + KD S+EE+  +ALA E     + G ++ K I VP +LVN+V+
Sbjct  779  IKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

519) leuS in NC_017430


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  699 bits (2642),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 414/834 (50%), Positives = 601/834 (73%), Gaps = 22/834 (2%)

Query  3    YDPGLIEEKWQKFWENEQVFKAEEDETKTKYYVLDMFPYPSGAGLHVGHLIGYTATDIVA  62
            YD   IE KWQ FW +++ FK+  D +K K+Y LDMFPYPSGAGLHVGH  GYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRAQGFSVLHPMGWDSFGLPAEQYAIRTGTHPRETTEKNIANFKKQLTAMGFSYDESR  122
            R+KRAQG +VLHPMGWD+FGLPAEQYA+ TG +P E T  NIANFK+Q+ A+GFSYD  R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EFATSDPEYYKWTQKLFLILYEKGLAYMADMAVNYCPELGTVLSNEEI-ENGFSVDGGYP  181
            E  T+DP+YYKWTQ +F  LYEKGLAY A+++VN   ELGT ++NEE+  +G S  GGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRMLRQWVLRITAFADQLLEGLDELDWPESVKQLQKNWIGKSSGASVNFATEHGVIE-  240
            V R+ +RQW+L+ITA+A++LLE+L+E+DWPES+K++Q+NWIGKS+GA+V F   +   + 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  -VFTTRPDTLIGVSFLALAPEHPLVDLLTSDEQKAVVAQYIKETQSKSERDRISEMKTKS  299
             VFTTRPDTL+G ++  LAPEH+LVD +T+ +Q   VA+Y +++  KS+  R    K K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  300  GVFTGSYAKHPVTHKLIPIWIADYVLMGFGSGAVMGVPAHDERDLLFAEQFNLPVVSVLN  359
            GV TGSYA +PV  K +P+WIADYVL ++G+GA+M+VPAHDERD  FA QFNL +++VL+
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  360  KEGVCINSCCE-GFH-----LDGLSGEEAKQYVINFLEENHLGAAKIAYKLRDWLFSRQR  413
               V   +  E G+H     LDGL    A   +++ LE + +G  +++Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  414  YWGEPIPIIHFEDGSCRPLRDYELPLLPPEIQDYRPEGVGQGPLAKVREWVQVFDTETQR  473
            YWGEPIPIIH EDG+  ++ + ELPL+ P  +D RP G G++PLA+V +W++V   +  +
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  474  AGKRETHTMPQWAGSCWYYLRFCDAHNSAAPWAKEKEQYWMPVDLYIGGAEHAVLHLLYA  533
             G+RET+TMPQWAGS WYYLR+ D+HN+      E  + W+PVD+Y+GGAEHAVLHLLYA
Sbjct  484  -GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  534  RFWHQVFYEAGIVSTPEPFKKLVNQGLVLATSYRIPGKGYIYPE-IAKEENGKWVAPSGE  592
            RFWH+V+Y+ G+V+T EPF+KL NQG++L+TSYR +  + +  + + K + +     +GE
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  593  ELDVRQEKMSKSKLNGVDPQILIDEFGADAVRMYAMFSGPLDKNKLWSNQGVAGCRRFLN  652
            EL+    KMSKS  N V+P+ +++++GAD++R+Y MF GPLD +  WS++G+ G R+FL+
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  653  RFYEMVSSDRVKEDNNFEGLSLAHKLVQRVTDAIEKLSLNTIPSSFMEFINDFVK----L  708
            R Y ++++  + E+N+     + +  V+ VT+ ++++ +NT  + +M F+N   K    +
Sbjct  663  RVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLF  722

Query  709  AVYPKSAVEMAVRALAPIAPHISEELW-VLLGNSPGVQKSGWPSVLPEYLEGQTVTIVVQ  767
            + Y+K+ V++    +AP+APH++EELW  L +++ ++    WPS     L  + V IVVQ
Sbjct  723  SDYAKGFVQL----IAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQ  778

Query  768  VNGKLRARLDIMKDASKEEV--LALARESASKYLEGCEVKKAIFVPARLVNFVV  819
            ++GK++A+L + KD S+EE+  +ALA E     + G ++ K I VP +LVN+V+
Sbjct  779  IKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

520) leuS in NC_017432


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  699 bits (2642),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 414/834 (50%), Positives = 601/834 (73%), Gaps = 22/834 (2%)

Query  3    YDPGLIEEKWQKFWENEQVFKAEEDETKTKYYVLDMFPYPSGAGLHVGHLIGYTATDIVA  62
            YD   IE KWQ FW +++ FK+  D +K K+Y LDMFPYPSGAGLHVGH  GYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRAQGFSVLHPMGWDSFGLPAEQYAIRTGTHPRETTEKNIANFKKQLTAMGFSYDESR  122
            R+KRAQG +VLHPMGWD+FGLPAEQYA+ TG +P E T  NIANFK+Q+ A+GFSYD  R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EFATSDPEYYKWTQKLFLILYEKGLAYMADMAVNYCPELGTVLSNEEI-ENGFSVDGGYP  181
            E  T+DP+YYKWTQ +F  LYEKGLAY A+++VN   ELGT ++NEE+  +G S  GGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRMLRQWVLRITAFADQLLEGLDELDWPESVKQLQKNWIGKSSGASVNFATEHGVIE-  240
            V R+ +RQW+L+ITA+A++LLE+L+E+DWPES+K++Q+NWIGKS+GA+V F   +   + 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  -VFTTRPDTLIGVSFLALAPEHPLVDLLTSDEQKAVVAQYIKETQSKSERDRISEMKTKS  299
             VFTTRPDTL+G ++  LAPEH+LVD +T+ +Q   VA+Y +++  KS+  R    K K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  300  GVFTGSYAKHPVTHKLIPIWIADYVLMGFGSGAVMGVPAHDERDLLFAEQFNLPVVSVLN  359
            GV TGSYA +PV  K +P+WIADYVL ++G+GA+M+VPAHDERD  FA QFNL +++VL+
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  360  KEGVCINSCCE-GFH-----LDGLSGEEAKQYVINFLEENHLGAAKIAYKLRDWLFSRQR  413
               V   +  E G+H     LDGL    A   +++ LE + +G  +++Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  414  YWGEPIPIIHFEDGSCRPLRDYELPLLPPEIQDYRPEGVGQGPLAKVREWVQVFDTETQR  473
            YWGEPIPIIH EDG+  ++ + ELPL+ P  +D RP G G++PLA+V +W++V   +  +
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  474  AGKRETHTMPQWAGSCWYYLRFCDAHNSAAPWAKEKEQYWMPVDLYIGGAEHAVLHLLYA  533
             G+RET+TMPQWAGS WYYLR+ D+HN+      E  + W+PVD+Y+GGAEHAVLHLLYA
Sbjct  484  -GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  534  RFWHQVFYEAGIVSTPEPFKKLVNQGLVLATSYRIPGKGYIYPE-IAKEENGKWVAPSGE  592
            RFWH+V+Y+ G+V+T EPF+KL NQG++L+TSYR +  + +  + + K + +     +GE
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  593  ELDVRQEKMSKSKLNGVDPQILIDEFGADAVRMYAMFSGPLDKNKLWSNQGVAGCRRFLN  652
            EL+    KMSKS  N V+P+ +++++GAD++R+Y MF GPLD +  WS++G+ G R+FL+
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  653  RFYEMVSSDRVKEDNNFEGLSLAHKLVQRVTDAIEKLSLNTIPSSFMEFINDFVK----L  708
            R Y ++++  + E+N+     + +  V+ VT+ ++++ +NT  + +M F+N   K    +
Sbjct  663  RVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLF  722

Query  709  AVYPKSAVEMAVRALAPIAPHISEELW-VLLGNSPGVQKSGWPSVLPEYLEGQTVTIVVQ  767
            + Y+K+ V++    +AP+APH++EELW  L +++ ++    WPS     L  + V IVVQ
Sbjct  723  SDYAKGFVQL----IAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQ  778

Query  768  VNGKLRARLDIMKDASKEEV--LALARESASKYLEGCEVKKAIFVPARLVNFVV  819
            ++GK++A+L + KD S+EE+  +ALA E     + G ++ K I VP +LVN+V+
Sbjct  779  IKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

521) leuS in NC_017429


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  699 bits (2642),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 414/834 (50%), Positives = 601/834 (73%), Gaps = 22/834 (2%)

Query  3    YDPGLIEEKWQKFWENEQVFKAEEDETKTKYYVLDMFPYPSGAGLHVGHLIGYTATDIVA  62
            YD   IE KWQ FW +++ FK+  D +K K+Y LDMFPYPSGAGLHVGH  GYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRAQGFSVLHPMGWDSFGLPAEQYAIRTGTHPRETTEKNIANFKKQLTAMGFSYDESR  122
            R+KRAQG +VLHPMGWD+FGLPAEQYA+ TG +P E T  NIANFK+Q+ A+GFSYD  R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EFATSDPEYYKWTQKLFLILYEKGLAYMADMAVNYCPELGTVLSNEEI-ENGFSVDGGYP  181
            E  T+DP+YYKWTQ +F  LYEKGLAY A+++VN   ELGT ++NEE+  +G S  GGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRMLRQWVLRITAFADQLLEGLDELDWPESVKQLQKNWIGKSSGASVNFATEHGVIE-  240
            V R+ +RQW+L+ITA+A++LLE+L+E+DWPES+K++Q+NWIGKS+GA+V F   +   + 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  -VFTTRPDTLIGVSFLALAPEHPLVDLLTSDEQKAVVAQYIKETQSKSERDRISEMKTKS  299
             VFTTRPDTL+G ++  LAPEH+LVD +T+ +Q   VA+Y +++  KS+  R    K K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  300  GVFTGSYAKHPVTHKLIPIWIADYVLMGFGSGAVMGVPAHDERDLLFAEQFNLPVVSVLN  359
            GV TGSYA +PV  K +P+WIADYVL ++G+GA+M+VPAHDERD  FA QFNL +++VL+
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  360  KEGVCINSCCE-GFH-----LDGLSGEEAKQYVINFLEENHLGAAKIAYKLRDWLFSRQR  413
               V   +  E G+H     LDGL    A   +++ LE + +G  +++Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  414  YWGEPIPIIHFEDGSCRPLRDYELPLLPPEIQDYRPEGVGQGPLAKVREWVQVFDTETQR  473
            YWGEPIPIIH EDG+  ++ + ELPL+ P  +D RP G G++PLA+V +W++V   +  +
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  474  AGKRETHTMPQWAGSCWYYLRFCDAHNSAAPWAKEKEQYWMPVDLYIGGAEHAVLHLLYA  533
             G+RET+TMPQWAGS WYYLR+ D+HN+      E  + W+PVD+Y+GGAEHAVLHLLYA
Sbjct  484  -GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  534  RFWHQVFYEAGIVSTPEPFKKLVNQGLVLATSYRIPGKGYIYPE-IAKEENGKWVAPSGE  592
            RFWH+V+Y+ G+V+T EPF+KL NQG++L+TSYR +  + +  + + K + +     +GE
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  593  ELDVRQEKMSKSKLNGVDPQILIDEFGADAVRMYAMFSGPLDKNKLWSNQGVAGCRRFLN  652
            EL+    KMSKS  N V+P+ +++++GAD++R+Y MF GPLD +  WS++G+ G R+FL+
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  653  RFYEMVSSDRVKEDNNFEGLSLAHKLVQRVTDAIEKLSLNTIPSSFMEFINDFVK----L  708
            R Y ++++  + E+N+     + +  V+ VT+ ++++ +NT  + +M F+N   K    +
Sbjct  663  RVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLF  722

Query  709  AVYPKSAVEMAVRALAPIAPHISEELW-VLLGNSPGVQKSGWPSVLPEYLEGQTVTIVVQ  767
            + Y+K+ V++    +AP+APH++EELW  L +++ ++    WPS     L  + V IVVQ
Sbjct  723  SDYAKGFVQL----IAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQ  778

Query  768  VNGKLRARLDIMKDASKEEV--LALARESASKYLEGCEVKKAIFVPARLVNFVV  819
            ++GK++A+L + KD S+EE+  +ALA E     + G ++ K I VP +LVN+V+
Sbjct  779  IKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

522) SOTONG1_00216 in NC_020941


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  699 bits (2642),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 414/834 (50%), Positives = 601/834 (73%), Gaps = 22/834 (2%)

Query  3    YDPGLIEEKWQKFWENEQVFKAEEDETKTKYYVLDMFPYPSGAGLHVGHLIGYTATDIVA  62
            YD   IE KWQ FW +++ FK+  D +K K+Y LDMFPYPSGAGLHVGH  GYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRAQGFSVLHPMGWDSFGLPAEQYAIRTGTHPRETTEKNIANFKKQLTAMGFSYDESR  122
            R+KRAQG +VLHPMGWD+FGLPAEQYA+ TG +P E T  NIANFK+Q+ A+GFSYD  R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EFATSDPEYYKWTQKLFLILYEKGLAYMADMAVNYCPELGTVLSNEEI-ENGFSVDGGYP  181
            E  T+DP+YYKWTQ +F  LYEKGLAY A+++VN   ELGT ++NEE+  +G S  GGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRMLRQWVLRITAFADQLLEGLDELDWPESVKQLQKNWIGKSSGASVNFATEHGVIE-  240
            V R+ +RQW+L+ITA+A++LLE+L+E+DWPES+K++Q+NWIGKS+GA+V F   +   + 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  -VFTTRPDTLIGVSFLALAPEHPLVDLLTSDEQKAVVAQYIKETQSKSERDRISEMKTKS  299
             VFTTRPDTL+G ++  LAPEH+LVD +T+ +Q   VA+Y +++  KS+  R    K K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  300  GVFTGSYAKHPVTHKLIPIWIADYVLMGFGSGAVMGVPAHDERDLLFAEQFNLPVVSVLN  359
            GV TGSYA +PV  K +P+WIADYVL ++G+GA+M+VPAHDERD  FA QFNL +++VL+
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  360  KEGVCINSCCE-GFH-----LDGLSGEEAKQYVINFLEENHLGAAKIAYKLRDWLFSRQR  413
               V   +  E G+H     LDGL    A   +++ LE + +G  +++Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  414  YWGEPIPIIHFEDGSCRPLRDYELPLLPPEIQDYRPEGVGQGPLAKVREWVQVFDTETQR  473
            YWGEPIPIIH EDG+  ++ + ELPL+ P  +D RP G G++PLA+V +W++V   +  +
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  474  AGKRETHTMPQWAGSCWYYLRFCDAHNSAAPWAKEKEQYWMPVDLYIGGAEHAVLHLLYA  533
             G+RET+TMPQWAGS WYYLR+ D+HN+      E  + W+PVD+Y+GGAEHAVLHLLYA
Sbjct  484  -GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  534  RFWHQVFYEAGIVSTPEPFKKLVNQGLVLATSYRIPGKGYIYPE-IAKEENGKWVAPSGE  592
            RFWH+V+Y+ G+V+T EPF+KL NQG++L+TSYR +  + +  + + K + +     +GE
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  593  ELDVRQEKMSKSKLNGVDPQILIDEFGADAVRMYAMFSGPLDKNKLWSNQGVAGCRRFLN  652
            EL+    KMSKS  N V+P+ +++++GAD++R+Y MF GPLD +  WS++G+ G R+FL+
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  653  RFYEMVSSDRVKEDNNFEGLSLAHKLVQRVTDAIEKLSLNTIPSSFMEFINDFVK----L  708
            R Y ++++  + E+N+     + +  V+ VT+ ++++ +NT  + +M F+N   K    +
Sbjct  663  RVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLF  722

Query  709  AVYPKSAVEMAVRALAPIAPHISEELW-VLLGNSPGVQKSGWPSVLPEYLEGQTVTIVVQ  767
            + Y+K+ V++    +AP+APH++EELW  L +++ ++    WPS     L  + V IVVQ
Sbjct  723  SDYAKGFVQL----IAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQ  778

Query  768  VNGKLRARLDIMKDASKEEV--LALARESASKYLEGCEVKKAIFVPARLVNFVV  819
            ++GK++A+L + KD S+EE+  +ALA E     + G ++ K I VP +LVN+V+
Sbjct  779  IKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

523) leuS in NC_020511


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  699 bits (2642),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 414/834 (50%), Positives = 601/834 (73%), Gaps = 22/834 (2%)

Query  3    YDPGLIEEKWQKFWENEQVFKAEEDETKTKYYVLDMFPYPSGAGLHVGHLIGYTATDIVA  62
            YD   IE KWQ FW +++ FK+  D +K K+Y LDMFPYPSGAGLHVGH  GYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRAQGFSVLHPMGWDSFGLPAEQYAIRTGTHPRETTEKNIANFKKQLTAMGFSYDESR  122
            R+KRAQG +VLHPMGWD+FGLPAEQYA+ TG +P E T  NIANFK+Q+ A+GFSYD  R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EFATSDPEYYKWTQKLFLILYEKGLAYMADMAVNYCPELGTVLSNEEI-ENGFSVDGGYP  181
            E  T+DP+YYKWTQ +F  LYEKGLAY A+++VN   ELGT ++NEE+  +G S  GGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRMLRQWVLRITAFADQLLEGLDELDWPESVKQLQKNWIGKSSGASVNFATEHGVIE-  240
            V R+ +RQW+L+ITA+A++LLE+L+E+DWPES+K++Q+NWIGKS+GA+V F   +   + 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  -VFTTRPDTLIGVSFLALAPEHPLVDLLTSDEQKAVVAQYIKETQSKSERDRISEMKTKS  299
             VFTTRPDTL+G ++  LAPEH+LVD +T+ +Q   VA+Y +++  KS+  R    K K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  300  GVFTGSYAKHPVTHKLIPIWIADYVLMGFGSGAVMGVPAHDERDLLFAEQFNLPVVSVLN  359
            GV TGSYA +PV  K +P+WIADYVL ++G+GA+M+VPAHDERD  FA QFNL +++VL+
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  360  KEGVCINSCCE-GFH-----LDGLSGEEAKQYVINFLEENHLGAAKIAYKLRDWLFSRQR  413
               V   +  E G+H     LDGL    A   +++ LE + +G  +++Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  414  YWGEPIPIIHFEDGSCRPLRDYELPLLPPEIQDYRPEGVGQGPLAKVREWVQVFDTETQR  473
            YWGEPIPIIH EDG+  ++ + ELPL+ P  +D RP G G++PLA+V +W++V   +  +
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  474  AGKRETHTMPQWAGSCWYYLRFCDAHNSAAPWAKEKEQYWMPVDLYIGGAEHAVLHLLYA  533
             G+RET+TMPQWAGS WYYLR+ D+HN+      E  + W+PVD+Y+GGAEHAVLHLLYA
Sbjct  484  -GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  534  RFWHQVFYEAGIVSTPEPFKKLVNQGLVLATSYRIPGKGYIYPE-IAKEENGKWVAPSGE  592
            RFWH+V+Y+ G+V+T EPF+KL NQG++L+TSYR +  + +  + + K + +     +GE
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  593  ELDVRQEKMSKSKLNGVDPQILIDEFGADAVRMYAMFSGPLDKNKLWSNQGVAGCRRFLN  652
            EL+    KMSKS  N V+P+ +++++GAD++R+Y MF GPLD +  WS++G+ G R+FL+
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  653  RFYEMVSSDRVKEDNNFEGLSLAHKLVQRVTDAIEKLSLNTIPSSFMEFINDFVK----L  708
            R Y ++++  + E+N+     + +  V+ VT+ ++++ +NT  + +M F+N   K    +
Sbjct  663  RVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLF  722

Query  709  AVYPKSAVEMAVRALAPIAPHISEELW-VLLGNSPGVQKSGWPSVLPEYLEGQTVTIVVQ  767
            + Y+K+ V++    +AP+APH++EELW  L +++ ++    WPS     L  + V IVVQ
Sbjct  723  SDYAKGFVQL----IAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQ  778

Query  768  VNGKLRARLDIMKDASKEEV--LALARESASKYLEGCEVKKAIFVPARLVNFVV  819
            ++GK++A+L + KD S+EE+  +ALA E     + G ++ K I VP +LVN+V+
Sbjct  779  IKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

524) leuS in NC_020512


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  699 bits (2642),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 414/834 (50%), Positives = 601/834 (73%), Gaps = 22/834 (2%)

Query  3    YDPGLIEEKWQKFWENEQVFKAEEDETKTKYYVLDMFPYPSGAGLHVGHLIGYTATDIVA  62
            YD   IE KWQ FW +++ FK+  D +K K+Y LDMFPYPSGAGLHVGH  GYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRAQGFSVLHPMGWDSFGLPAEQYAIRTGTHPRETTEKNIANFKKQLTAMGFSYDESR  122
            R+KRAQG +VLHPMGWD+FGLPAEQYA+ TG +P E T  NIANFK+Q+ A+GFSYD  R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EFATSDPEYYKWTQKLFLILYEKGLAYMADMAVNYCPELGTVLSNEEI-ENGFSVDGGYP  181
            E  T+DP+YYKWTQ +F  LYEKGLAY A+++VN   ELGT ++NEE+  +G S  GGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRMLRQWVLRITAFADQLLEGLDELDWPESVKQLQKNWIGKSSGASVNFATEHGVIE-  240
            V R+ +RQW+L+ITA+A++LLE+L+E+DWPES+K++Q+NWIGKS+GA+V F   +   + 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  -VFTTRPDTLIGVSFLALAPEHPLVDLLTSDEQKAVVAQYIKETQSKSERDRISEMKTKS  299
             VFTTRPDTL+G ++  LAPEH+LVD +T+ +Q   VA+Y +++  KS+  R    K K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  300  GVFTGSYAKHPVTHKLIPIWIADYVLMGFGSGAVMGVPAHDERDLLFAEQFNLPVVSVLN  359
            GV TGSYA +PV  K +P+WIADYVL ++G+GA+M+VPAHDERD  FA QFNL +++VL+
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  360  KEGVCINSCCE-GFH-----LDGLSGEEAKQYVINFLEENHLGAAKIAYKLRDWLFSRQR  413
               V   +  E G+H     LDGL    A   +++ LE + +G  +++Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  414  YWGEPIPIIHFEDGSCRPLRDYELPLLPPEIQDYRPEGVGQGPLAKVREWVQVFDTETQR  473
            YWGEPIPIIH EDG+  ++ + ELPL+ P  +D RP G G++PLA+V +W++V   +  +
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  474  AGKRETHTMPQWAGSCWYYLRFCDAHNSAAPWAKEKEQYWMPVDLYIGGAEHAVLHLLYA  533
             G+RET+TMPQWAGS WYYLR+ D+HN+      E  + W+PVD+Y+GGAEHAVLHLLYA
Sbjct  484  -GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  534  RFWHQVFYEAGIVSTPEPFKKLVNQGLVLATSYRIPGKGYIYPE-IAKEENGKWVAPSGE  592
            RFWH+V+Y+ G+V+T EPF+KL NQG++L+TSYR +  + +  + + K + +     +GE
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  593  ELDVRQEKMSKSKLNGVDPQILIDEFGADAVRMYAMFSGPLDKNKLWSNQGVAGCRRFLN  652
            EL+    KMSKS  N V+P+ +++++GAD++R+Y MF GPLD +  WS++G+ G R+FL+
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  653  RFYEMVSSDRVKEDNNFEGLSLAHKLVQRVTDAIEKLSLNTIPSSFMEFINDFVK----L  708
            R Y ++++  + E+N+     + +  V+ VT+ ++++ +NT  + +M F+N   K    +
Sbjct  663  RVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLF  722

Query  709  AVYPKSAVEMAVRALAPIAPHISEELW-VLLGNSPGVQKSGWPSVLPEYLEGQTVTIVVQ  767
            + Y+K+ V++    +AP+APH++EELW  L +++ ++    WPS     L  + V IVVQ
Sbjct  723  SDYAKGFVQL----IAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQ  778

Query  768  VNGKLRARLDIMKDASKEEV--LALARESASKYLEGCEVKKAIFVPARLVNFVV  819
            ++GK++A+L + KD S+EE+  +ALA E     + G ++ K I VP +LVN+V+
Sbjct  779  IKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

525) leuS in NC_021892


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  699 bits (2642),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 414/834 (50%), Positives = 601/834 (73%), Gaps = 22/834 (2%)

Query  3    YDPGLIEEKWQKFWENEQVFKAEEDETKTKYYVLDMFPYPSGAGLHVGHLIGYTATDIVA  62
            YD   IE KWQ FW +++ FK+  D +K K+Y LDMFPYPSGAGLHVGH  GYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRAQGFSVLHPMGWDSFGLPAEQYAIRTGTHPRETTEKNIANFKKQLTAMGFSYDESR  122
            R+KRAQG +VLHPMGWD+FGLPAEQYA+ TG +P E T  NIANFK+Q+ A+GFSYD  R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EFATSDPEYYKWTQKLFLILYEKGLAYMADMAVNYCPELGTVLSNEEI-ENGFSVDGGYP  181
            E  T+DP+YYKWTQ +F  LYEKGLAY A+++VN   ELGT ++NEE+  +G S  GGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRMLRQWVLRITAFADQLLEGLDELDWPESVKQLQKNWIGKSSGASVNFATEHGVIE-  240
            V R+ +RQW+L+ITA+A++LLE+L+E+DWPES+K++Q+NWIGKS+GA+V F   +   + 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  -VFTTRPDTLIGVSFLALAPEHPLVDLLTSDEQKAVVAQYIKETQSKSERDRISEMKTKS  299
             VFTTRPDTL+G ++  LAPEH+LVD +T+ +Q   VA+Y +++  KS+  R    K K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  300  GVFTGSYAKHPVTHKLIPIWIADYVLMGFGSGAVMGVPAHDERDLLFAEQFNLPVVSVLN  359
            GV TGSYA +PV  K +P+WIADYVL ++G+GA+M+VPAHDERD  FA QFNL +++VL+
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  360  KEGVCINSCCE-GFH-----LDGLSGEEAKQYVINFLEENHLGAAKIAYKLRDWLFSRQR  413
               V   +  E G+H     LDGL    A   +++ LE + +G  +++Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  414  YWGEPIPIIHFEDGSCRPLRDYELPLLPPEIQDYRPEGVGQGPLAKVREWVQVFDTETQR  473
            YWGEPIPIIH EDG+  ++ + ELPL+ P  +D RP G G++PLA+V +W++V   +  +
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  474  AGKRETHTMPQWAGSCWYYLRFCDAHNSAAPWAKEKEQYWMPVDLYIGGAEHAVLHLLYA  533
             G+RET+TMPQWAGS WYYLR+ D+HN+      E  + W+PVD+Y+GGAEHAVLHLLYA
Sbjct  484  -GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  534  RFWHQVFYEAGIVSTPEPFKKLVNQGLVLATSYRIPGKGYIYPE-IAKEENGKWVAPSGE  592
            RFWH+V+Y+ G+V+T EPF+KL NQG++L+TSYR +  + +  + + K + +     +GE
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  593  ELDVRQEKMSKSKLNGVDPQILIDEFGADAVRMYAMFSGPLDKNKLWSNQGVAGCRRFLN  652
            EL+    KMSKS  N V+P+ +++++GAD++R+Y MF GPLD +  WS++G+ G R+FL+
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  653  RFYEMVSSDRVKEDNNFEGLSLAHKLVQRVTDAIEKLSLNTIPSSFMEFINDFVK----L  708
            R Y ++++  + E+N+     + +  V+ VT+ ++++ +NT  + +M F+N   K    +
Sbjct  663  RVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLF  722

Query  709  AVYPKSAVEMAVRALAPIAPHISEELW-VLLGNSPGVQKSGWPSVLPEYLEGQTVTIVVQ  767
            + Y+K+ V++    +AP+APH++EELW  L +++ ++    WPS     L  + V IVVQ
Sbjct  723  SDYAKGFVQL----IAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQ  778

Query  768  VNGKLRARLDIMKDASKEEV--LALARESASKYLEGCEVKKAIFVPARLVNFVV  819
            ++GK++A+L + KD S+EE+  +ALA E     + G ++ K I VP +LVN+V+
Sbjct  779  IKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

526) SOTONK1_00216 in NC_020965


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  699 bits (2642),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 414/834 (50%), Positives = 601/834 (73%), Gaps = 22/834 (2%)

Query  3    YDPGLIEEKWQKFWENEQVFKAEEDETKTKYYVLDMFPYPSGAGLHVGHLIGYTATDIVA  62
            YD   IE KWQ FW +++ FK+  D +K K+Y LDMFPYPSGAGLHVGH  GYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRAQGFSVLHPMGWDSFGLPAEQYAIRTGTHPRETTEKNIANFKKQLTAMGFSYDESR  122
            R+KRAQG +VLHPMGWD+FGLPAEQYA+ TG +P E T  NIANFK+Q+ A+GFSYD  R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EFATSDPEYYKWTQKLFLILYEKGLAYMADMAVNYCPELGTVLSNEEI-ENGFSVDGGYP  181
            E  T+DP+YYKWTQ +F  LYEKGLAY A+++VN   ELGT ++NEE+  +G S  GGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRMLRQWVLRITAFADQLLEGLDELDWPESVKQLQKNWIGKSSGASVNFATEHGVIE-  240
            V R+ +RQW+L+ITA+A++LLE+L+E+DWPES+K++Q+NWIGKS+GA+V F   +   + 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  -VFTTRPDTLIGVSFLALAPEHPLVDLLTSDEQKAVVAQYIKETQSKSERDRISEMKTKS  299
             VFTTRPDTL+G ++  LAPEH+LVD +T+ +Q   VA+Y +++  KS+  R    K K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  300  GVFTGSYAKHPVTHKLIPIWIADYVLMGFGSGAVMGVPAHDERDLLFAEQFNLPVVSVLN  359
            GV TGSYA +PV  K +P+WIADYVL ++G+GA+M+VPAHDERD  FA QFNL +++VL+
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  360  KEGVCINSCCE-GFH-----LDGLSGEEAKQYVINFLEENHLGAAKIAYKLRDWLFSRQR  413
               V   +  E G+H     LDGL    A   +++ LE + +G  +++Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  414  YWGEPIPIIHFEDGSCRSLRDYELPLLPPEIQDYRPEGVGQGPLAKVREWVQVFDTETQR  473
            YWGEPIPIIH EDG+  ++ + ELPL+ P  +D RP G G++PLA+V +W++V   +  +
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  474  AGKRETHTMPQWAGSCWYYLRFCDAHNSAAPWAKEKEQYWMPVDLYIGGAEHAVLHLLYA  533
             G+RET+TMPQWAGS WYYLR+ D+HN+      E  + W+PVD+Y+GGAEHAVLHLLYA
Sbjct  484  -GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  534  RFWHQVFYEAGIVSTPEPFKKLVNQGLVLATSYRIPGKGYIYPE-IAKEENGKWVAPSGE  592
            RFWH+V+Y+ G+V+T EPF+KL NQG++L+TSYR +  + +  + + K + +     +GE
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  593  ELDVRQEKMSKSKLNGVDPQILIDEFGADAVRMYAMFSGPLDKNKLWSNQGVAGCRRFLN  652
            EL+    KMSKS  N V+P+ +++++GAD++R+Y MF GPLD +  WS++G+ G R+FL+
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  653  RFYEMVSSDRVKEDNNFEGLSLAHKLVQRVTDAIEKLSLNTIPSSFMEFINDFVK----L  708
            R Y ++++  + E+N+     + +  V+ VT+ ++++ +NT  + +M F+N   K    +
Sbjct  663  RVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLF  722

Query  709  AVYPKSAVEMAVRALAPIAPHISEELW-VLLGNSPGVQKSGWPSVLPEYLEGQTVTIVVQ  767
            + Y+K+ V++    +AP+APH++EELW  L +++ ++    WPS     L  + V IVVQ
Sbjct  723  SDYAKGFVQL----IAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQ  778

Query  768  VNGKLRARLDIMKDASKEEV--LALARESASKYLEGCEVKKAIFVPARLVNFVV  819
            ++GK++A+L + KD S+EE+  +ALA E     + G ++ K I VP +LVN+V+
Sbjct  779  IKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

527) leuS in NC_017441


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  699 bits (2642),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 414/834 (50%), Positives = 601/834 (73%), Gaps = 22/834 (2%)

Query  3    YDPGLIEEKWQKFWENEQVFKAEEDETKTKYYVLDMFPYPSGAGLHVGHLIGYTATDIVA  62
            YD   IE KWQ FW +++ FK+  D +K K+Y LDMFPYPSGAGLHVGH  GYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRAQGFSVLHPMGWDSFGLPAEQYAIRTGTHPRETTEKNIANFKKQLTAMGFSYDESR  122
            R+KRAQG +VLHPMGWD+FGLPAEQYA+ TG +P E T  NIANFK+Q+ A+GFSYD  R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EFATSDPEYYKWTQKLFLILYEKGLAYMADMAVNYCPELGTVLSNEEI-ENGFSVDGGYP  181
            E  T+DP+YYKWTQ +F  LYEKGLAY A+++VN   ELGT ++NEE+  +G S  GGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRMLRQWVLRITAFADQLLEGLDELDWPESVKQLQKNWIGKSSGASVNFATEHGVIE-  240
            V R+ +RQW+L+ITA+A++LLE+L+E+DWPES+K++Q+NWIGKS+GA+V F   +   + 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  -VFTTRPDTLIGVSFLALAPEHPLVDLLTSDEQKAVVAQYIKETQSKSERDRISEMKTKS  299
             VFTTRPDTL+G ++  LAPEH+LVD +T+ +Q   VA+Y +++  KS+  R    K K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  300  GVFTGSYAKHPVTHKLIPIWIADYVLMGFGSGAVMGVPAHDERDLLFAEQFNLPVVSVLN  359
            GV TGSYA +PV  K +P+WIADYVL ++G+GA+M+VPAHDERD  FA QFNL +++VL+
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  360  KEGVCINSCCE-GFH-----LDGLSGEEAKQYVINFLEENHLGAAKIAYKLRDWLFSRQR  413
               V   +  E G+H     LDGL    A   +++ LE + +G  +++Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  414  YWGEPIPIIHFEDGSCRPLRDYELPLLPPEIQDYRPEGVGQGPLAKVREWVQVFDTETQR  473
            YWGEPIPIIH EDG+  ++ + ELPL+ P  +D RP G G++PLA+V +W++V   +  +
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  474  AGKRETHTMPQWAGSCWYYLRFCDAHNSAAPWAKEKEQYWMPVDLYIGGAEHAVLHLLYA  533
             G+RET+TMPQWAGS WYYLR+ D+HN+      E  + W+PVD+Y+GGAEHAVLHLLYA
Sbjct  484  -GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  534  RFWHQVFYEAGIVSTPEPFKKLVNQGLVLATSYRIPGKGYIYPE-IAKEENGKWVAPSGE  592
            RFWH+V+Y+ G+V+T EPF+KL NQG++L+TSYR +  + +  + + K + +     +GE
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  593  ELDVRQEKMSKSKLNGVDPQILIDEFGADAVRMYAMFSGPLDKNKLWSNQGVAGCRRFLN  652
            EL+    KMSKS  N V+P+ +++++GAD++R+Y MF GPLD +  WS++G+ G R+FL+
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  653  RFYEMVSSDRVKEDNNFEGLSLAHKLVQRVTDAIEKLSLNTIPSSFMEFINDFVK----L  708
            R Y ++++  + E+N+     + +  V+ VT+ ++++ +NT  + +M F+N   K    +
Sbjct  663  RVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLF  722

Query  709  AVYPKSAVEMAVRALAPIAPHISEELW-VLLGNSPGVQKSGWPSVLPEYLEGQTVTIVVQ  767
            + Y+K+ V++    +AP+APH++EELW  L +++ ++    WPS     L  + V IVVQ
Sbjct  723  SDYAKGFVQL----IAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQ  778

Query  768  VNGKLRARLDIMKDASKEEV--LALARESASKYLEGCEVKKAIFVPARLVNFVV  819
            ++GK++A+L + KD S+EE+  +ALA E     + G ++ K I VP +LVN+V+
Sbjct  779  IKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

528) SOTONE4_00215 in NC_020969


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  699 bits (2642),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 414/834 (50%), Positives = 601/834 (73%), Gaps = 22/834 (2%)

Query  3    YDPGLIEEKWQKFWENEQVFKAEEDETKTKYYVLDMFPYPSGAGLHVGHLIGYTATDIVA  62
            YD   IE KWQ FW +++ FK+  D +K K+Y LDMFPYPSGAGLHVGH  GYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRAQGFSVLHPMGWDSFGLPAEQYAIRTGTHPRETTEKNIANFKKQLTAMGFSYDESR  122
            R+KRAQG +VLHPMGWD+FGLPAEQYA+ TG +P E T  NIANFK+Q+ A+GFSYD  R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EFATSDPEYYKWTQKLFLILYEKGLAYMADMAVNYCPELGTVLSNEEI-ENGFSVDGGYP  181
            E  T+DP+YYKWTQ +F  LYEKGLAY A+++VN   ELGT ++NEE+  +G S  GGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRMLRQWVLRITAFADQLLEGLDELDWPESVKQLQKNWIGKSSGASVNFATEHGVIE-  240
            V R+ +RQW+L+ITA+A++LLE+L+E+DWPES+K++Q+NWIGKS+GA+V F   +   + 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  -VFTTRPDTLIGVSFLALAPEHPLVDLLTSDEQKAVVAQYIKETQSKSERDRISEMKTKS  299
             VFTTRPDTL+G ++  LAPEH+LVD +T+ +Q   VA+Y +++  KS+  R    K K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  300  GVFTGSYAKHPVTHKLIPIWIADYVLMGFGSGAVMGVPAHDERDLLFAEQFNLPVVSVLN  359
            GV TGSYA +PV  K +P+WIADYVL ++G+GA+M+VPAHDERD  FA QFNL +++VL+
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  360  KEGVCINSCCE-GFH-----LDGLSGEEAKQYVINFLEENHLGAAKIAYKLRDWLFSRQR  413
               V   +  E G+H     LDGL    A   +++ LE + +G  +++Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  414  YWGEPIPIIHFEDGSCRPLRDYELPLLPPEIQDYRPEGVGQGPLAKVREWVQVFDTETQR  473
            YWGEPIPIIH EDG+  ++ + ELPL+ P  +D RP G G++PLA+V +W++V   +  +
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  474  AGKRETHTMPQWAGSCWYYLRFCDAHNSAAPWAKEKEQYWMPVDLYIGGAEHAVLHLLYA  533
             G+RET+TMPQWAGS WYYLR+ D+HN+      E  + W+PVD+Y+GGAEHAVLHLLYA
Sbjct  484  -GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  534  RFWHQVFYEAGIVSTPEPFKKLVNQGLVLATSYRIPGKGYIYPE-IAKEENGKWVAPSGE  592
            RFWH+V+Y+ G+V+T EPF+KL NQG++L+TSYR +  + +  + + K + +     +GE
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  593  ELDVRQEKMSKSKLNGVDPQILIDEFGADAVRMYAMFSGPLDKNKLWSNQGVAGCRRFLN  652
            EL+    KMSKS  N V+P+ +++++GAD++R+Y MF GPLD +  WS++G+ G R+FL+
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  653  RFYEMVSSDRVKEDNNFEGLSLAHKLVQRVTDAIEKLSLNTIPSSFMEFINDFVK----L  708
            R Y ++++  + E+N+     + +  V+ VT+ ++++ +NT  + +M F+N   K    +
Sbjct  663  RVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLF  722

Query  709  AVYPKSAVEMAVRALAPIAPHISEELW-VLLGNSPGVQKSGWPSVLPEYLEGQTVTIVVQ  767
            + Y+K+ V++    +AP+APH++EELW  L +++ ++    WPS     L  + V IVVQ
Sbjct  723  SDYAKGFVQL----IAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQ  778

Query  768  VNGKLRARLDIMKDASKEEV--LALARESASKYLEGCEVKKAIFVPARLVNFVV  819
            ++GK++A+L + KD S+EE+  +ALA E     + G ++ K I VP +LVN+V+
Sbjct  779  IKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

529) SOTONF3_00216 in NC_020964


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  699 bits (2642),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 414/834 (50%), Positives = 601/834 (73%), Gaps = 22/834 (2%)

Query  3    YDPGLIEEKWQKFWENEQVFKAEEDETKTKYYVLDMFPYPSGAGLHVGHLIGYTATDIVA  62
            YD   IE KWQ FW +++ FK+  D +K K+Y LDMFPYPSGAGLHVGH  GYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRAQGFSVLHPMGWDSFGLPAEQYAIRTGTHPRETTEKNIANFKKQLTAMGFSYDESR  122
            R+KRAQG +VLHPMGWD+FGLPAEQYA+ TG +P E T  NIANFK+Q+ A+GFSYD  R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EFATSDPEYYKWTQKLFLILYEKGLAYMADMAVNYCPELGTVLSNEEI-ENGFSVDGGYP  181
            E  T+DP+YYKWTQ +F  LYEKGLAY A+++VN   ELGT ++NEE+  +G S  GGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRMLRQWVLRITAFADQLLEGLDELDWPESVKQLQKNWIGKSSGASVNFATEHGVIE-  240
            V R+ +RQW+L+ITA+A++LLE+L+E+DWPES+K++Q+NWIGKS+GA+V F   +   + 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  -VFTTRPDTLIGVSFLALAPEHPLVDLLTSDEQKAVVAQYIKETQSKSERDRISEMKTKS  299
             VFTTRPDTL+G ++  LAPEH+LVD +T+ +Q   VA+Y +++  KS+  R    K K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  300  GVFTGSYAKHPVTHKLIPIWIADYVLMGFGSGAVMGVPAHDERDLLFAEQFNLPVVSVLN  359
            GV TGSYA +PV  K +P+WIADYVL ++G+GA+M+VPAHDERD  FA QFNL +++VL+
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  360  KEGVCINSCCE-GFH-----LDGLSGEEAKQYVINFLEENHLGAAKIAYKLRDWLFSRQR  413
               V   +  E G+H     LDGL    A   +++ LE + +G  +++Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  414  YWGEPIPIIHFEDGSCRPLRDYELPLLPPEIQDYRPEGVGQGPLAKVREWVQVFDTETQR  473
            YWGEPIPIIH EDG+  ++ + ELPL+ P  +D RP G G++PLA+V +W++V   +  +
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  474  AGKRETHTMPQWAGSCWYYLRFCDAHNSAAPWAKEKEQYWMPVDLYIGGAEHAVLHLLYA  533
             G+RET+TMPQWAGS WYYLR+ D+HN+      E  + W+PVD+Y+GGAEHAVLHLLYA
Sbjct  484  -GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  534  RFWHQVFYEAGIVSTPEPFKKLVNQGLVLATSYRIPGKGYIYPE-IAKEENGKWVAPSGE  592
            RFWH+V+Y+ G+V+T EPF+KL NQG++L+TSYR +  + +  + + K + +     +GE
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  593  ELDVRQEKMSKSKLNGVDPQILIDEFGADAVRMYAMFSGPLDKNKLWSNQGVAGCRRFLN  652
            EL+    KMSKS  N V+P+ +++++GAD++R+Y MF GPLD +  WS++G+ G R+FL+
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  653  RFYEMVSSDRVKEDNNFEGLSLAHKLVQRVTDAIEKLSLNTIPSSFMEFINDFVK----L  708
            R Y ++++  + E+N+     + +  V+ VT+ ++++ +NT  + +M F+N   K    +
Sbjct  663  RVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLF  722

Query  709  AVYPKSAVEMAVRALAPIAPHISEELW-VLLGNSPGVQKSGWPSVLPEYLEGQTVTIVVQ  767
            + Y+K+ V++    +AP+APH++EELW  L +++ ++    WPS     L  + V IVVQ
Sbjct  723  SDYAKGFVQL----IAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQ  778

Query  768  VNGKLRARLDIMKDASKEEV--LALARESASKYLEGCEVKKAIFVPARLVNFVV  819
            ++GK++A+L + KD S+EE+  +ALA E     + G ++ K I VP +LVN+V+
Sbjct  779  IKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

530) O170_01130 in NC_022106


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  699 bits (2642),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 414/834 (50%), Positives = 601/834 (73%), Gaps = 22/834 (2%)

Query  3    YDPGLIEEKWQKFWENEQVFKAEEDETKTKYYVLDMFPYPSGAGLHVGHLIGYTATDIVA  62
            YD   IE KWQ FW +++ FK+  D +K K+Y LDMFPYPSGAGLHVGH  GYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRAQGFSVLHPMGWDSFGLPAEQYAIRTGTHPRETTEKNIANFKKQLTAMGFSYDESR  122
            R+KRAQG +VLHPMGWD+FGLPAEQYA+ TG +P E T  NIANFK+Q+ A+GFSYD  R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EFATSDPEYYKWTQKLFLILYEKGLAYMADMAVNYCPELGTVLSNEEI-ENGFSVDGGYP  181
            E  T+DP+YYKWTQ +F  LYEKGLAY A+++VN   ELGT ++NEE+  +G S  GGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRMLRQWVLRITAFADQLLEGLDELDWPESVKQLQKNWIGKSSGASVNFATEHGVIE-  240
            V R+ +RQW+L+ITA+A++LLE+L+E+DWPES+K++Q+NWIGKS+GA+V F   +   + 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  -VFTTRPDTLIGVSFLALAPEHPLVDLLTSDEQKAVVAQYIKETQSKSERDRISEMKTKS  299
             VFTTRPDTL+G ++  LAPEH+LVD +T+ +Q   VA+Y +++  KS+  R    K K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  300  GVFTGSYAKHPVTHKLIPIWIADYVLMGFGSGAVMGVPAHDERDLLFAEQFNLPVVSVLN  359
            GV TGSYA +PV  K +P+WIADYVL ++G+GA+M+VPAHDERD  FA QFNL +++VL+
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  360  KEGVCINSCCE-GFH-----LDGLSGEEAKQYVINFLEENHLGAAKIAYKLRDWLFSRQR  413
               V   +  E G+H     LDGL    A   +++ LE + +G  +++Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  414  YWGEPIPIIHFEDGSCRPLRDYELPLLPPEIQDYRPEGVGQGPLAKVREWVQVFDTETQR  473
            YWGEPIPIIH EDG+  ++ + ELPL+ P  +D RP G G++PLA+V +W++V   +  +
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  474  AGKRETHTMPQWAGSCWYYLRFCDAHNSAAPWAKEKEQYWMPVDLYIGGAEHAVLHLLYA  533
             G+RET+TMPQWAGS WYYLR+ D+HN+      E  + W+PVD+Y+GGAEHAVLHLLYA
Sbjct  484  -GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  534  RFWHQVFYEAGIVSTPEPFKKLVNQGLVLATSYRIPGKGYIYPE-IAKEENGKWVAPSGE  592
            RFWH+V+Y+ G+V+T EPF+KL NQG++L+TSYR +  + +  + + K + +     +GE
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  593  ELDVRQEKMSKSKLNGVDPQILIDEFGADAVRMYAMFSGPLDKNKLWSNQGVAGCRRFLN  652
            EL+    KMSKS  N V+P+ +++++GAD++R+Y MF GPLD +  WS++G+ G R+FL+
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  653  RFYEMVSSDRVKEDNNFEGLSLAHKLVQRVTDAIEKLSLNTIPSSFMEFINDFVK----L  708
            R Y ++++  + E+N+     + +  V+ VT+ ++++ +NT  + +M F+N   K    +
Sbjct  663  RVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLF  722

Query  709  AVYPKSAVEMAVRALAPIAPHISEELW-VLLGNSPGVQKSGWPSVLPEYLEGQTVTIVVQ  767
            + Y+K+ V++    +AP+APH++EELW  L +++ ++    WPS     L  + V IVVQ
Sbjct  723  SDYAKGFVQL----IAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQ  778

Query  768  VNGKLRARLDIMKDASKEEV--LALARESASKYLEGCEVKKAIFVPARLVNFVV  819
            ++GK++A+L + KD S+EE+  +ALA E     + G ++ K I VP +LVN+V+
Sbjct  779  IKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

531) O173_01135 in NC_022107


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  699 bits (2642),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 414/834 (50%), Positives = 601/834 (73%), Gaps = 22/834 (2%)

Query  3    YDPGLIEEKWQKFWENEQVFKAEEDETKTKYYVLDMFPYPSGAGLHVGHLIGYTATDIVA  62
            YD   IE KWQ FW +++ FK+  D +K K+Y LDMFPYPSGAGLHVGH  GYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRAQGFSVLHPMGWDSFGLPAEQYAIRTGTHPRETTEKNIANFKKQLTAMGFSYDESR  122
            R+KRAQG +VLHPMGWD+FGLPAEQYA+ TG +P E T  NIANFK+Q+ A+GFSYD  R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EFATSDPEYYKWTQKLFLILYEKGLAYMADMAVNYCPELGTVLSNEEI-ENGFSVDGGYP  181
            E  T+DP+YYKWTQ +F  LYEKGLAY A+++VN   ELGT ++NEE+  +G S  GGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRMLRQWVLRITAFADQLLEGLDELDWPESVKQLQKNWIGKSSGASVNFATEHGVIE-  240
            V R+ +RQW+L+ITA+A++LLE+L+E+DWPES+K++Q+NWIGKS+GA+V F   +   + 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  -VFTTRPDTLIGVSFLALAPEHPLVDLLTSDEQKAVVAQYIKETQSKSERDRISEMKTKS  299
             VFTTRPDTL+G ++  LAPEH+LVD +T+ +Q   VA+Y +++  KS+  R    K K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  300  GVFTGSYAKHPVTHKLIPIWIADYVLMGFGSGAVMGVPAHDERDLLFAEQFNLPVVSVLN  359
            GV TGSYA +PV  K +P+WIADYVL ++G+GA+M+VPAHDERD  FA QFNL +++VL+
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  360  KEGVCINSCCE-GFH-----LDGLSGEEAKQYVINFLEENHLGAAKIAYKLRDWLFSRQR  413
               V   +  E G+H     LDGL    A   +++ LE + +G  +++Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  414  YWGEPIPIIHFEDGSCRPLRDYELPLLPPEIQDYRPEGVGQGPLAKVREWVQVFDTETQR  473
            YWGEPIPIIH EDG+  ++ + ELPL+ P  +D RP G G++PLA+V +W++V   +  +
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  474  AGKRETHTMPQWAGSCWYYLRFCDAHNSAAPWAKEKEQYWMPVDLYIGGAEHAVLHLLYA  533
             G+RET+TMPQWAGS WYYLR+ D+HN+      E  + W+PVD+Y+GGAEHAVLHLLYA
Sbjct  484  -GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  534  RFWHQVFYEAGIVSTPEPFKKLVNQGLVLATSYRIPGKGYIYPE-IAKEENGKWVAPSGE  592
            RFWH+V+Y+ G+V+T EPF+KL NQG++L+TSYR +  + +  + + K + +     +GE
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  593  ELDVRQEKMSKSKLNGVDPQILIDEFGADAVRMYAMFSGPLDKNKLWSNQGVAGCRRFLN  652
            EL+    KMSKS  N V+P+ +++++GAD++R+Y MF GPLD +  WS++G+ G R+FL+
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  653  RFYEMVSSDRVKEDNNFEGLSLAHKLVQRVTDAIEKLSLNTIPSSFMEFINDFVK----L  708
            R Y ++++  + E+N+     + +  V+ VT+ ++++ +NT  + +M F+N   K    +
Sbjct  663  RVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLF  722

Query  709  AVYPKSAVEMAVRALAPIAPHISEELW-VLLGNSPGVQKSGWPSVLPEYLEGQTVTIVVQ  767
            + Y+K+ V++    +AP+APH++EELW  L +++ ++    WPS     L  + V IVVQ
Sbjct  723  SDYAKGFVQL----IAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQ  778

Query  768  VNGKLRARLDIMKDASKEEV--LALARESASKYLEGCEVKKAIFVPARLVNFVV  819
            ++GK++A+L + KD S+EE+  +ALA E     + G ++ K I VP +LVN+V+
Sbjct  779  IKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

532) O177_01130 in NC_022109


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  699 bits (2642),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 414/834 (50%), Positives = 601/834 (73%), Gaps = 22/834 (2%)

Query  3    YDPGLIEEKWQKFWENEQVFKAEEDETKTKYYVLDMFPYPSGAGLHVGHLIGYTATDIVA  62
            YD   IE KWQ FW +++ FK+  D +K K+Y LDMFPYPSGAGLHVGH  GYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRAQGFSVLHPMGWDSFGLPAEQYAIRTGTHPRETTEKNIANFKKQLTAMGFSYDESR  122
            R+KRAQG +VLHPMGWD+FGLPAEQYA+ TG +P E T  NIANFK+Q+ A+GFSYD  R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EFATSDPEYYKWTQKLFLILYEKGLAYMADMAVNYCPELGTVLSNEEI-ENGFSVDGGYP  181
            E  T+DP+YYKWTQ +F  LYEKGLAY A+++VN   ELGT ++NEE+  +G S  GGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRMLRQWVLRITAFADQLLEGLDELDWPESVKQLQKNWIGKSSGASVNFATEHGVIE-  240
            V R+ +RQW+L+ITA+A++LLE+L+E+DWPES+K++Q+NWIGKS+GA+V F   +   + 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  -VFTTRPDTLIGVSFLALAPEHPLVDLLTSDEQKAVVAQYIKETQSKSERDRISEMKTKS  299
             VFTTRPDTL+G ++  LAPEH+LVD +T+ +Q   VA+Y +++  KS+  R    K K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  300  GVFTGSYAKHPVTHKLIPIWIADYVLMGFGSGAVMGVPAHDERDLLFAEQFNLPVVSVLN  359
            GV TGSYA +PV  K +P+WIADYVL ++G+GA+M+VPAHDERD  FA QFNL +++VL+
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  360  KEGVCINSCCE-GFH-----LDGLSGEEAKQYVINFLEENHLGAAKIAYKLRDWLFSRQR  413
               V   +  E G+H     LDGL    A   +++ LE + +G  +++Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  414  YWGEPIPIIHFEDGSCRPLRDYELPLLPPEIQDYRPEGVGQGPLAKVREWVQVFDTETQR  473
            YWGEPIPIIH EDG+  ++ + ELPL+ P  +D RP G G++PLA+V +W++V   +  +
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  474  AGKRETHTMPQWAGSCWYYLRFCDAHNSAAPWAKEKEQYWMPVDLYIGGAEHAVLHLLYA  533
             G+RET+TMPQWAGS WYYLR+ D+HN+      E  + W+PVD+Y+GGAEHAVLHLLYA
Sbjct  484  -GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  534  RFWHQVFYEAGIVSTPEPFKKLVNQGLVLATSYRIPGKGYIYPE-IAKEENGKWVAPSGE  592
            RFWH+V+Y+ G+V+T EPF+KL NQG++L+TSYR +  + +  + + K + +     +GE
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  593  ELDVRQEKMSKSKLNGVDPQILIDEFGADAVRMYAMFSGPLDKNKLWSNQGVAGCRRFLN  652
            EL+    KMSKS  N V+P+ +++++GAD++R+Y MF GPLD +  WS++G+ G R+FL+
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  653  RFYEMVSSDRVKEDNNFEGLSLAHKLVQRVTDAIEKLSLNTIPSSFMEFINDFVK----L  708
            R Y ++++  + E+N+     + +  V+ VT+ ++++ +NT  + +M F+N   K    +
Sbjct  663  RVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLF  722

Query  709  AVYPKSAVEMAVRALAPIAPHISEELW-VLLGNSPGVQKSGWPSVLPEYLEGQTVTIVVQ  767
            + Y+K+ V++    +AP+APH++EELW  L +++ ++    WPS     L  + V IVVQ
Sbjct  723  SDYAKGFVQL----IAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQ  778

Query  768  VNGKLRARLDIMKDASKEEV--LALARESASKYLEGCEVKKAIFVPARLVNFVV  819
            ++GK++A+L + KD S+EE+  +ALA E     + G ++ K I VP +LVN+V+
Sbjct  779  IKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

533) O169_01140 in NC_022117


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  699 bits (2642),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 414/834 (50%), Positives = 601/834 (73%), Gaps = 22/834 (2%)

Query  3    YDPGLIEEKWQKFWENEQVFKAEEDETKTKYYVLDMFPYPSGAGLHVGHLIGYTATDIVA  62
            YD   IE KWQ FW +++ FK+  D +K K+Y LDMFPYPSGAGLHVGH  GYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRAQGFSVLHPMGWDSFGLPAEQYAIRTGTHPRETTEKNIANFKKQLTAMGFSYDESR  122
            R+KRAQG +VLHPMGWD+FGLPAEQYA+ TG +P E T  NIANFK+Q+ A+GFSYD  R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EFATSDPEYYKWTQKLFLILYEKGLAYMADMAVNYCPELGTVLSNEEI-ENGFSVDGGYP  181
            E  T+DP+YYKWTQ +F  LYEKGLAY A+++VN   ELGT ++NEE+  +G S  GGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRMLRQWVLRITAFADQLLEGLDELDWPESVKQLQKNWIGKSSGASVNFATEHGVIE-  240
            V R+ +RQW+L+ITA+A++LLE+L+E+DWPES+K++Q+NWIGKS+GA+V F   +   + 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  -VFTTRPDTLIGVSFLALAPEHPLVDLLTSDEQKAVVAQYIKETQSKSERDRISEMKTKS  299
             VFTTRPDTL+G ++  LAPEH+LVD +T+ +Q   VA+Y +++  KS+  R    K K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  300  GVFTGSYAKHPVTHKLIPIWIADYVLMGFGSGAVMGVPAHDERDLLFAEQFNLPVVSVLN  359
            GV TGSYA +PV  K +P+WIADYVL ++G+GA+M+VPAHDERD  FA QFNL +++VL+
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  360  KEGVCINSCCE-GFH-----LDGLSGEEAKQYVINFLEENHLGAAKIAYKLRDWLFSRQR  413
               V   +  E G+H     LDGL    A   +++ LE + +G  +++Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  414  YWGEPIPIIHFEDGSCRPLRDYELPLLPPEIQDYRPEGVGQGPLAKVREWVQVFDTETQR  473
            YWGEPIPIIH EDG+  ++ + ELPL+ P  +D RP G G++PLA+V +W++V   +  +
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  474  AGKRETHTMPQWAGSCWYYLRFCDAHNSAAPWAKEKEQYWMPVDLYIGGAEHAVLHLLYA  533
             G+RET+TMPQWAGS WYYLR+ D+HN+      E  + W+PVD+Y+GGAEHAVLHLLYA
Sbjct  484  -GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  534  RFWHQVFYEAGIVSTPEPFKKLVNQGLVLATSYRIPGKGYIYPE-IAKEENGKWVAPSGE  592
            RFWH+V+Y+ G+V+T EPF+KL NQG++L+TSYR +  + +  + + K + +     +GE
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  593  ELDVRQEKMSKSKLNGVDPQILIDEFGADAVRMYAMFSGPLDKNKLWSNQGVAGCRRFLN  652
            EL+    KMSKS  N V+P+ +++++GAD++R+Y MF GPLD +  WS++G+ G R+FL+
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  653  RFYEMVSSDRVKEDNNFEGLSLAHKLVQRVTDAIEKLSLNTIPSSFMEFINDFVK----L  708
            R Y ++++  + E+N+     + +  V+ VT+ ++++ +NT  + +M F+N   K    +
Sbjct  663  RVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLF  722

Query  709  AVYPKSAVEMAVRALAPIAPHISEELW-VLLGNSPGVQKSGWPSVLPEYLEGQTVTIVVQ  767
            + Y+K+ V++    +AP+APH++EELW  L +++ ++    WPS     L  + V IVVQ
Sbjct  723  SDYAKGFVQL----IAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQ  778

Query  768  VNGKLRARLDIMKDASKEEV--LALARESASKYLEGCEVKKAIFVPARLVNFVV  819
            ++GK++A+L + KD S+EE+  +ALA E     + G ++ K I VP +LVN+V+
Sbjct  779  IKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

534) O172_01130 in NC_022118


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  699 bits (2642),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 414/834 (50%), Positives = 601/834 (73%), Gaps = 22/834 (2%)

Query  3    YDPGLIEEKWQKFWENEQVFKAEEDETKTKYYVLDMFPYPSGAGLHVGHLIGYTATDIVA  62
            YD   IE KWQ FW +++ FK+  D +K K+Y LDMFPYPSGAGLHVGH  GYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRAQGFSVLHPMGWDSFGLPAEQYAIRTGTHPRETTEKNIANFKKQLTAMGFSYDESR  122
            R+KRAQG +VLHPMGWD+FGLPAEQYA+ TG +P E T  NIANFK+Q+ A+GFSYD  R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EFATSDPEYYKWTQKLFLILYEKGLAYMADMAVNYCPELGTVLSNEEI-ENGFSVDGGYP  181
            E  T+DP+YYKWTQ +F  LYEKGLAY A+++VN   ELGT ++NEE+  +G S  GGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRMLRQWVLRITAFADQLLEGLDELDWPESVKQLQKNWIGKSSGASVNFATEHGVIE-  240
            V R+ +RQW+L+ITA+A++LLE+L+E+DWPES+K++Q+NWIGKS+GA+V F   +   + 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  -VFTTRPDTLIGVSFLALAPEHPLVDLLTSDEQKAVVAQYIKETQSKSERDRISEMKTKS  299
             VFTTRPDTL+G ++  LAPEH+LVD +T+ +Q   VA+Y +++  KS+  R    K K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  300  GVFTGSYAKHPVTHKLIPIWIADYVLMGFGSGAVMGVPAHDERDLLFAEQFNLPVVSVLN  359
            GV TGSYA +PV  K +P+WIADYVL ++G+GA+M+VPAHDERD  FA QFNL +++VL+
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  360  KEGVCINSCCE-GFH-----LDGLSGEEAKQYVINFLEENHLGAAKIAYKLRDWLFSRQR  413
               V   +  E G+H     LDGL    A   +++ LE + +G  +++Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  414  YWGEPIPIIHFEDGSCRPLRDYELPLLPPEIQDYRPEGVGQGPLAKVREWVQVFDTETQR  473
            YWGEPIPIIH EDG+  ++ + ELPL+ P  +D RP G G++PLA+V +W++V   +  +
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  474  AGKRETHTMPQWAGSCWYYLRFCDAHNSAAPWAKEKEQYWMPVDLYIGGAEHAVLHLLYA  533
             G+RET+TMPQWAGS WYYLR+ D+HN+      E  + W+PVD+Y+GGAEHAVLHLLYA
Sbjct  484  -GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  534  RFWHQVFYEAGIVSTPEPFKKLVNQGLVLATSYRIPGKGYIYPE-IAKEENGKWVAPSGE  592
            RFWH+V+Y+ G+V+T EPF+KL NQG++L+TSYR +  + +  + + K + +     +GE
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  593  ELDVRQEKMSKSKLNGVDPQILIDEFGADAVRMYAMFSGPLDKNKLWSNQGVAGCRRFLN  652
            EL+    KMSKS  N V+P+ +++++GAD++R+Y MF GPLD +  WS++G+ G R+FL+
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  653  RFYEMVSSDRVKEDNNFEGLSLAHKLVQRVTDAIEKLSLNTIPSSFMEFINDFVK----L  708
            R Y ++++  + E+N+     + +  V+ VT+ ++++ +NT  + +M F+N   K    +
Sbjct  663  RVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLF  722

Query  709  AVYPKSAVEMAVRALAPIAPHISEELW-VLLGNSPGVQKSGWPSVLPEYLEGQTVTIVVQ  767
            + Y+K+ V++    +AP+APH++EELW  L +++ ++    WPS     L  + V IVVQ
Sbjct  723  SDYAKGFVQL----IAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQ  778

Query  768  VNGKLRARLDIMKDASKEEV--LALARESASKYLEGCEVKKAIFVPARLVNFVV  819
            ++GK++A+L + KD S+EE+  +ALA E     + G ++ K I VP +LVN+V+
Sbjct  779  IKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

535) O176_01130 in NC_022119


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  699 bits (2642),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 414/834 (50%), Positives = 601/834 (73%), Gaps = 22/834 (2%)

Query  3    YDPGLIEEKWQKFWENEQVFKAEEDETKTKYYVLDMFPYPSGAGLHVGHLIGYTATDIVA  62
            YD   IE KWQ FW +++ FK+  D +K K+Y LDMFPYPSGAGLHVGH  GYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRAQGFSVLHPMGWDSFGLPAEQYAIRTGTHPRETTEKNIANFKKQLTAMGFSYDESR  122
            R+KRAQG +VLHPMGWD+FGLPAEQYA+ TG +P E T  NIANFK+Q+ A+GFSYD  R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EFATSDPEYYKWTQKLFLILYEKGLAYMADMAVNYCPELGTVLSNEEI-ENGFSVDGGYP  181
            E  T+DP+YYKWTQ +F  LYEKGLAY A+++VN   ELGT ++NEE+  +G S  GGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRMLRQWVLRITAFADQLLEGLDELDWPESVKQLQKNWIGKSSGASVNFATEHGVIE-  240
            V R+ +RQW+L+ITA+A++LLE+L+E+DWPES+K++Q+NWIGKS+GA+V F   +   + 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  -VFTTRPDTLIGVSFLALAPEHPLVDLLTSDEQKAVVAQYIKETQSKSERDRISEMKTKS  299
             VFTTRPDTL+G ++  LAPEH+LVD +T+ +Q   VA+Y +++  KS+  R    K K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  300  GVFTGSYAKHPVTHKLIPIWIADYVLMGFGSGAVMGVPAHDERDLLFAEQFNLPVVSVLN  359
            GV TGSYA +PV  K +P+WIADYVL ++G+GA+M+VPAHDERD  FA QFNL +++VL+
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  360  KEGVCINSCCE-GFH-----LDGLSGEEAKQYVINFLEENHLGAAKIAYKLRDWLFSRQR  413
               V   +  E G+H     LDGL    A   +++ LE + +G  +++Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  414  YWGEPIPIIHFEDGSCRPLRDYELPLLPPEIQDYRPEGVGQGPLAKVREWVQVFDTETQR  473
            YWGEPIPIIH EDG+  ++ + ELPL+ P  +D RP G G++PLA+V +W++V   +  +
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  474  AGKRETHTMPQWAGSCWYYLRFCDAHNSAAPWAKEKEQYWMPVDLYIGGAEHAVLHLLYA  533
             G+RET+TMPQWAGS WYYLR+ D+HN+      E  + W+PVD+Y+GGAEHAVLHLLYA
Sbjct  484  -GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  534  RFWHQVFYEAGIVSTPEPFKKLVNQGLVLATSYRIPGKGYIYPE-IAKEENGKWVAPSGE  592
            RFWH+V+Y+ G+V+T EPF+KL NQG++L+TSYR +  + +  + + K + +     +GE
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  593  ELDVRQEKMSKSKLNGVDPQILIDEFGADAVRMYAMFSGPLDKNKLWSNQGVAGCRRFLN  652
            EL+    KMSKS  N V+P+ +++++GAD++R+Y MF GPLD +  WS++G+ G R+FL+
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  653  RFYEMVSSDRVKEDNNFEGLSLAHKLVQRVTDAIEKLSLNTIPSSFMEFINDFVK----L  708
            R Y ++++  + E+N+     + +  V+ VT+ ++++ +NT  + +M F+N   K    +
Sbjct  663  RVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLF  722

Query  709  AVYPKSAVEMAVRALAPIAPHISEELW-VLLGNSPGVQKSGWPSVLPEYLEGQTVTIVVQ  767
            + Y+K+ V++    +AP+APH++EELW  L +++ ++    WPS     L  + V IVVQ
Sbjct  723  SDYAKGFVQL----IAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQ  778

Query  768  VNGKLRARLDIMKDASKEEV--LALARESASKYLEGCEVKKAIFVPARLVNFVV  819
            ++GK++A+L + KD S+EE+  +ALA E     + G ++ K I VP +LVN+V+
Sbjct  779  IKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

536) O180_01140 in NC_022121


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  699 bits (2642),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 414/834 (50%), Positives = 601/834 (73%), Gaps = 22/834 (2%)

Query  3    YDPGLIEEKWQKFWENEQVFKAEEDETKTKYYVLDMFPYPSGAGLHVGHLIGYTATDIVA  62
            YD   IE KWQ FW +++ FK+  D +K K+Y LDMFPYPSGAGLHVGH  GYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRAQGFSVLHPMGWDSFGLPAEQYAIRTGTHPRETTEKNIANFKKQLTAMGFSYDESR  122
            R+KRAQG +VLHPMGWD+FGLPAEQYA+ TG +P E T  NIANFK+Q+ A+GFSYD  R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EFATSDPEYYKWTQKLFLILYEKGLAYMADMAVNYCPELGTVLSNEEI-ENGFSVDGGYP  181
            E  T+DP+YYKWTQ +F  LYEKGLAY A+++VN   ELGT ++NEE+  +G S  GGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRMLRQWVLRITAFADQLLEGLDELDWPESVKQLQKNWIGKSSGASVNFATEHGVIE-  240
            V R+ +RQW+L+ITA+A++LLE+L+E+DWPES+K++Q+NWIGKS+GA+V F   +   + 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  -VFTTRPDTLIGVSFLALAPEHPLVDLLTSDEQKAVVAQYIKETQSKSERDRISEMKTKS  299
             VFTTRPDTL+G ++  LAPEH+LVD +T+ +Q   VA+Y +++  KS+  R    K K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  300  GVFTGSYAKHPVTHKLIPIWIADYVLMGFGSGAVMGVPAHDERDLLFAEQFNLPVVSVLN  359
            GV TGSYA +PV  K +P+WIADYVL ++G+GA+M+VPAHDERD  FA QFNL +++VL+
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  360  KEGVCINSCCE-GFH-----LDGLSGEEAKQYVINFLEENHLGAAKIAYKLRDWLFSRQR  413
               V   +  E G+H     LDGL    A   +++ LE + +G  +++Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  414  YWGEPIPIIHFEDGSCRPLRDYELPLLPPEIQDYRPEGVGQGPLAKVREWVQVFDTETQR  473
            YWGEPIPIIH EDG+  ++ + ELPL+ P  +D RP G G++PLA+V +W++V   +  +
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  474  AGKRETHTMPQWAGSCWYYLRFCDAHNSAAPWAKEKEQYWMPVDLYIGGAEHAVLHLLYA  533
             G+RET+TMPQWAGS WYYLR+ D+HN+      E  + W+PVD+Y+GGAEHAVLHLLYA
Sbjct  484  -GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  534  RFWHQVFYEAGIVSTPEPFKKLVNQGLVLATSYRIPGKGYIYPE-IAKEENGKWVAPSGE  592
            RFWH+V+Y+ G+V+T EPF+KL NQG++L+TSYR +  + +  + + K + +     +GE
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  593  ELDVRQEKMSKSKLNGVDPQILIDEFGADAVRMYAMFSGPLDKNKLWSNQGVAGCRRFLN  652
            EL+    KMSKS  N V+P+ +++++GAD++R+Y MF GPLD +  WS++G+ G R+FL+
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  653  RFYEMVSSDRVKEDNNFEGLSLAHKLVQRVTDAIEKLSLNTIPSSFMEFINDFVK----L  708
            R Y ++++  + E+N+     + +  V+ VT+ ++++ +NT  + +M F+N   K    +
Sbjct  663  RVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLF  722

Query  709  AVYPKSAVEMAVRALAPIAPHISEELW-VLLGNSPGVQKSGWPSVLPEYLEGQTVTIVVQ  767
            + Y+K+ V++    +AP+APH++EELW  L +++ ++    WPS     L  + V IVVQ
Sbjct  723  SDYAKGFVQL----IAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQ  778

Query  768  VNGKLRARLDIMKDASKEEV--LALARESASKYLEGCEVKKAIFVPARLVNFVV  819
            ++GK++A+L + KD S+EE+  +ALA E     + G ++ K I VP +LVN+V+
Sbjct  779  IKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

537) EUR_16570 in NC_021010


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  699 bits (2642),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 418/840 (50%), Positives = 607/840 (73%), Gaps = 50/840 (5%)

Query  5    YNHKAIEKKWQEYWKEHETFKTDVWDFSKPKYYALDMFPYPSGVGLHAGHPEGYTATDIM  64
            Y+H AIE KWQ +W +++TFKT+  D SKPK+YALDMFPYPSG GLH GHPEGYTATDI+
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGT-DASKPKFYALDMFPYPSGAGLHVGHPEGYTATDIL  62

Query  65   SRMKRMQGYNVLHPMGYDSFGLPAEQYAVNTGHHPNGFTQKNIETFSKQLRELGFDYDWS  124
            SR KR QG NVLHPMG D+FGLPAEQYA++TG++P  FT  NI  F +Q+  LGF YDW 
Sbjct  63   SRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWD  122

Query  125  KMISTSDPEFYKWTQWIFKKLYEAGYAKHIDMPVNWCEELGTVLSNDEVI-DGKSERGGY  183
            + ++T+DP++YKWTQWIF KLYE G A + ++PVNW EELGT ++N+EV+ DG SERGGY
Sbjct  123  REVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGY  182

Query  184  PVVRKNMKQWVIDQPAFAEKLLEGLDEIDWPESTKEMQRNWIGKSTGVEVKFQIVGGG-E  242
            PVVRK M+QW++   A+AE+LLE+L+E+DWPES K+MQRNWIGKSTG +V F++ + + +
Sbjct  183  PVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  FSIFTTCIETIYGITFMVLAPDGDIVKGLMDRVENKEEVQAYIDETVKKSDMDRTELNKT  302
            F++FTT  +T++G T+ VLAP+  +V ++    ++ E V  Y  ++  KSD+ RT+L K 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTS-DQAEAVADYKRQASLKSDLARTDLAKE  301

Query  303  KSGCELKGLHCINPVNGKEVRMFIGDFVLASYGTGAVMAVPTHDQRDFEYAQAHDIEMIQ  362
            K+G    G   INPVNGKE+ + I+D+VLASYGTGA+MAVP+HD+RD E+A+  ++++I 
Sbjct  302  KTGV-WTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  363  VIDGADVSEHAFEKHDYLGKGCKLINSEEFTGMVVEDAKEAITAKLEKMGVAKRTVNYKF  422
            V++G++V E AF  ++        INS+ + G+    A   +   LE  GV++  V Y++
Sbjct  361  VLEGGNVEEAAFTEDGL------HINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRL  414

Query  423  REWIFARQRYWGEPVPCVYKEDGSIYFlpddelplvlpeledYKGK-NGKAPLENATEWK  481
            R+W+F+RQRYWGEP+P +  EDG+   +P+ ELPLVLP   D +    G +PL N T+W 
Sbjct  415  RDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWL  474

Query  482  QYDR-NGVKGTRETSTMPGSAGSSWYYMRYIDPHNDKEFANQELLKHWMPVDLYVGGPEH  540
            +  R +GVKG RET+TMP  AGSSWYY+RYIDPHN   +A++ELLK+W+PVD+YVGG+EH
Sbjct  475  EVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEH  534

Query  541  AVGHLMYSRIWNRFLFDQGLSPVKEPFKKLVHQGMILGSN----------GIKMGKRFPE  590
            AV HL+Y+R+W++ L+D G+ P KEPF+KL +QGMILG++            K+ KR   
Sbjct  535  AVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGS  594

Query  591  F----------------------VVNPSDVVEEYGADTLRLYEMFMGPLEVSKPWNDSNV  628
            F                      VVNP DVVE+YGADTLR+YEMFMGPL+ S +W++  +
Sbjct  595  FFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGL  654

Query  629  QGAKRFITRVWNFFTEPENIIEEDDGKLTRIYHQTVKKVTNDFEALGYNTAISQMMIFVN  688
            +G+++F+ RV  ++T  E I EE+ G L ++Y++TVK VT++ + + +NTAI+Q+M+FVN
Sbjct  655  EGSRKFLDRVYRLITTKE-ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVN  713

Query  689  EVYKAGRCPREFAEGLIKMLSCVCPHVGEEIWQRM-GHDDTIAFEPWPVYDEAKTVEDTV  747
               K ++   ++A G++++++   PH+GEE+WQ + + +++I++ PWP YDE+K VE+ V
Sbjct  714  AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDV  773

Query  748  EIAVQINGKTKGTLAIGKQDPKDEV--IAKAKDVIADKLTG-NIVKEIYVPGRIVNIVMK  804
            EI VQI+GK K+ L ++K+ +++E+  +A A++ +   ++G +I+K I VP ++VNIV+K
Sbjct  774  EIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

538) ERE_32020 in NC_021044


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  699 bits (2642),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 418/840 (50%), Positives = 607/840 (73%), Gaps = 50/840 (5%)

Query  5    YNHKAIEKKWQEYWKEHETFKTDVWDFSKPKYYALDMFPYPSGVGLHAGHPEGYTATDIM  64
            Y+H AIE KWQ +W +++TFKT+  D SKPK+YALDMFPYPSG GLH GHPEGYTATDI+
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGT-DASKPKFYALDMFPYPSGAGLHVGHPEGYTATDIL  62

Query  65   SRMKRMQGYNVLHPMGYDSFGLPAEQYAVNTGHHPNGFTQKNIETFSKQLRELGFDYDWS  124
            SR KR QG NVLHPMG D+FGLPAEQYA++TG++P  FT  NI  F +Q+  LGF YDW 
Sbjct  63   SRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWD  122

Query  125  KMISTSDPEFYKWTQWIFKKLYEAGYAKHIDMPVNWCEELGTVLSNDEVI-DGKSERGGY  183
            + ++T+DP++YKWTQWIF KLYE G A + ++PVNW EELGT ++N+EV+ DG SERGGY
Sbjct  123  REVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGY  182

Query  184  PVVRKNMKQWVIDQPAFAEKLLEGLDEIDWPESTKEMQRNWIGKSTGVEVKFQIVGGG-E  242
            PVVRK M+QW++   A+AE+LLE+L+E+DWPES K+MQRNWIGKSTG +V F++ + + +
Sbjct  183  PVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  FSIFTTCIETIYGITFMVLAPDGDIVKGLMDRVENKEEVQAYIDETVKKSDMDRTELNKT  302
            F++FTT  +T++G T+ VLAP+  +V ++    ++ E V  Y  ++  KSD+ RT+L K 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTS-DQAEAVADYKRQASLKSDLARTDLAKE  301

Query  303  KSGCELKGLHCINPVNGKEVRMFIGDFVLASYGTGAVMAVPTHDQRDFEYAQAHDIEMIQ  362
            K+G    G   INPVNGKE+ + I+D+VLASYGTGA+MAVP+HD+RD E+A+  ++++I 
Sbjct  302  KTGV-WTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  363  VIDGADVSEHAFEKHDYLGKGCKLINSEEFTGMVVEDAKEAITAKLEKMGVAKRTVNYKF  422
            V++G++V E AF  ++        INS+ + G+    A   +   LE  GV++  V Y++
Sbjct  361  VLEGGNVEEAAFTEDGL------HINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRL  414

Query  423  REWIFARQRYWGEPVPCVYKEDGSIYFlpddelplvlpeledYKGK-NGKAPLENATEWK  481
            R+W+F+RQRYWGEP+P +  EDG+   +P+ ELPLVLP   D +    G +PL N T+W 
Sbjct  415  RDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWL  474

Query  482  QYDR-NGVKGTRETSTMPGSAGSSWYYMRYIDPHNDKEFANQELLKHWMPVDLYVGGPEH  540
            +  R +GVKG RET+TMP  AGSSWYY+RYIDPHN   +A++ELLK+W+PVD+YVGG+EH
Sbjct  475  EVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEH  534

Query  541  AVGHLMYSRIWNRFLFDQGLSPVKEPFKKLVHQGMILGSN----------GIKMGKRFPE  590
            AV HL+Y+R+W++ L+D G+ P KEPF+KL +QGMILG++            K+ KR   
Sbjct  535  AVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGS  594

Query  591  F----------------------VVNPSDVVEEYGADTLRLYEMFMGPLEVSKPWNDSNV  628
            F                      VVNP DVVE+YGADTLR+YEMFMGPL+ S +W++  +
Sbjct  595  FFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGL  654

Query  629  QGAKRFITRVWNFFTEPENIIEEDDGKLTRIYHQTVKKVTNDFEALGYNTAISQMMIFVN  688
            +G+++F+ RV  ++T  E I EE+ G L ++Y++TVK VT++ + + +NTAI+Q+M+FVN
Sbjct  655  EGSRKFLDRVYRLITTKE-ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVN  713

Query  689  EVYKAGRCPREFAEGLIKMLSCVCPHVGEEIWQRM-GHDDTIAFEPWPVYDEAKTVEDTV  747
               K ++   ++A G++++++   PH+GEE+WQ + + +++I++ PWP YDE+K VE+ V
Sbjct  714  AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDV  773

Query  748  EIAVQINGKTKGTLAIGKQDPKDEV--IAKAKDVIADKLTG-NIVKEIYVPGRIVNIVMK  804
            EI VQI+GK K+ L ++K+ +++E+  +A A++ +   ++G +I+K I VP ++VNIV+K
Sbjct  774  EIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

539) SOTONIA1_00218 in NC_020970


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  698 bits (2638),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 413/834 (50%), Positives = 600/834 (72%), Gaps = 22/834 (2%)

Query  3    YDPGLIEEKWQKFWENEQVFKAEEDETKTKYYVLDMFPYPSGAGLHVGHLIGYTATDIVA  62
            YD   IE KWQ FW +++ FK+  D +K K+Y LDMFPYPSGAGLHVGH  GYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRAQGFSVLHPMGWDSFGLPAEQYAIRTGTHPRETTEKNIANFKKQLTAMGFSYDESR  122
            R+KRAQG +VLHPMGWD+FGLPAEQYA+ TG +P E T  NIANFK+Q+ A+GFSYD  R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EFATSDPEYYKWTQKLFLILYEKGLAYMADMAVNYCPELGTVLSNEEI-ENGFSVDGGYP  181
            E  T+DP+YYKWTQ +F  LYEKGLAY A+++VN   ELGT ++NEE+  +G S  GGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRMLRQWVLRITAFADQLLEGLDELDWPESVKQLQKNWIGKSSGASVNFATEHGVIE-  240
            V R+ +RQW+L+ITA+A++LLE+L+E+DWPES+K++Q+NWIGKS+GA+V F   +   + 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  -VFTTRPDTLIGVSFLALAPEHPLVDLLTSDEQKAVVAQYIKETQSKSERDRISEMKTKS  299
             VFTTRPDTL+G ++  LAPEH+LVD +T+ +Q   VA+Y +++  KS+  R    K K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  300  GVFTGSYAKHPVTHKLIPIWIADYVLMGFGSGAVMGVPAHDERDLLFAEQFNLPVVSVLN  359
            GV TGSYA +PV  K +P+WIADYVL ++G+GA+M+VPAHDERD  FA QFNL +++VL+
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  360  KEGVCINSCCE-GFH-----LDGLSGEEAKQYVINFLEENHLGAAKIAYKLRDWLFSRQR  413
               V   +  E G+H     LDGL    A   +++ LE + +G  +++Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  414  YWGEPIPIIHFEDGSCRPLRDYELPLLPPEIQDYRPEGVGQGPLAKVREWVQVFDTETQR  473
            YWGEPIPIIH EDG+  ++ + ELPL+ P  +D RP G G++PLA+V +W++V   +  +
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  474  AGKRETHTMPQWAGSCWYYLRFCDAHNSAAPWAKEKEQYWMPVDLYIGGAEHAVLHLLYA  533
             G+RET+TMPQWAGS WYYLR+ D+HN+      E  + W+PVD+Y+GGAEHAVLHLLYA
Sbjct  484  -GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  534  RFWHQVFYEAGIVSTPEPFKKLVNQGLVLATSYRIPGKGYIYPE-IAKEENGKWVAPSGE  592
            RFWH+V+Y+ G+V+T EPF+KL NQG++L+TSYR +  + +  + + K + +     +GE
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  593  ELDVRQEKMSKSKLNGVDPQILIDEFGADAVRMYAMFSGPLDKNKLWSNQGVAGCRRFLN  652
            EL+    KMSKS  N V+P+ +++++GAD++R+Y MF GPLD +  WS++G+ G R+FL+
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  653  RFYEMVSSDRVKEDNNFEGLSLAHKLVQRVTDAIEKLSLNTIPSSFMEFINDFVK----L  708
            R Y ++++  + E+N+     + +  V+ VT+ ++++ +NT  + +M F+N   K    +
Sbjct  663  RVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLF  722

Query  709  AVYPKSAVEMAVRALAPIAPHISEELW-VLLGNSPGVQKSGWPSVLPEYLEGQTVTIVVQ  767
            + Y+K+ V++    +AP+APH++EELW  L +++ ++    WPS     L  + V IVVQ
Sbjct  723  SDYAKGFVQL----IAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQ  778

Query  768  VNGKLRARLDIMKDASKKEV--LALARESASKYLEGCEVKKAIFVPARLVNFVV  819
            ++GK++A+L + KD S+ E+  +ALA E     + G ++ K I VP +LVN+V+
Sbjct  779  IKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

540) SOTONIA3_00218 in NC_020940


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  698 bits (2638),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 413/834 (50%), Positives = 600/834 (72%), Gaps = 22/834 (2%)

Query  3    YDPGLIEEKWQKFWENEQVFKAEEDETKTKYYVLDMFPYPSGAGLHVGHLIGYTATDIVA  62
            YD   IE KWQ FW +++ FK+  D +K K+Y LDMFPYPSGAGLHVGH  GYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRAQGFSVLHPMGWDSFGLPAEQYAIRTGTHPRETTEKNIANFKKQLTAMGFSYDESR  122
            R+KRAQG +VLHPMGWD+FGLPAEQYA+ TG +P E T  NIANFK+Q+ A+GFSYD  R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EFATSDPEYYKWTQKLFLILYEKGLAYMADMAVNYCPELGTVLSNEEI-ENGFSVDGGYP  181
            E  T+DP+YYKWTQ +F  LYEKGLAY A+++VN   ELGT ++NEE+  +G S  GGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRMLRQWVLRITAFADQLLEGLDELDWPESVKQLQKNWIGKSSGASVNFATEHGVIE-  240
            V R+ +RQW+L+ITA+A++LLE+L+E+DWPES+K++Q+NWIGKS+GA+V F   +   + 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  -VFTTRPDTLIGVSFLALAPEHPLVDLLTSDEQKAVVAQYIKETQSKSERDRISEMKTKS  299
             VFTTRPDTL+G ++  LAPEH+LVD +T+ +Q   VA+Y +++  KS+  R    K K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  300  GVFTGSYAKHPVTHKLIPIWIADYVLMGFGSGAVMGVPAHDERDLLFAEQFNLPVVSVLN  359
            GV TGSYA +PV  K +P+WIADYVL ++G+GA+M+VPAHDERD  FA QFNL +++VL+
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  360  KEGVCINSCCE-GFH-----LDGLSGEEAKQYVINFLEENHLGAAKIAYKLRDWLFSRQR  413
               V   +  E G+H     LDGL    A   +++ LE + +G  +++Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  414  YWGEPIPIIHFEDGSCRPLRDYELPLLPPEIQDYRPEGVGQGPLAKVREWVQVFDTETQR  473
            YWGEPIPIIH EDG+  ++ + ELPL+ P  +D RP G G++PLA+V +W++V   +  +
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  474  AGKRETHTMPQWAGSCWYYLRFCDAHNSAAPWAKEKEQYWMPVDLYIGGAEHAVLHLLYA  533
             G+RET+TMPQWAGS WYYLR+ D+HN+      E  + W+PVD+Y+GGAEHAVLHLLYA
Sbjct  484  -GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  534  RFWHQVFYEAGIVSTPEPFKKLVNQGLVLATSYRIPGKGYIYPE-IAKEENGKWVAPSGE  592
            RFWH+V+Y+ G+V+T EPF+KL NQG++L+TSYR +  + +  + + K + +     +GE
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  593  ELDVRQEKMSKSKLNGVDPQILIDEFGADAVRMYAMFSGPLDKNKLWSNQGVAGCRRFLN  652
            EL+    KMSKS  N V+P+ +++++GAD++R+Y MF GPLD +  WS++G+ G R+FL+
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  653  RFYEMVSSDRVKEDNNFEGLSLAHKLVQRVTDAIEKLSLNTIPSSFMEFINDFVK----L  708
            R Y ++++  + E+N+     + +  V+ VT+ ++++ +NT  + +M F+N   K    +
Sbjct  663  RVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLF  722

Query  709  AVYPKSAVEMAVRALAPIAPHISEELW-VLLGNSPGVQKSGWPSVLPEYLEGQTVTIVVQ  767
            + Y+K+ V++    +AP+APH++EELW  L +++ ++    WPS     L  + V IVVQ
Sbjct  723  SDYAKGFVQL----IAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQ  778

Query  768  VNGKLRARLDIMKDASKKEV--LALARESASKYLEGCEVKKAIFVPARLVNFVV  819
            ++GK++A+L + KD S+ E+  +ALA E     + G ++ K I VP +LVN+V+
Sbjct  779  IKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

541) O178_01135 in NC_022120


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  698 bits (2638),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 413/834 (50%), Positives = 600/834 (72%), Gaps = 22/834 (2%)

Query  3    YDPGLIEEKWQKFWENEQVFKAEEDETKTKYYVLDMFPYPSGAGLHVGHLIGYTATDIVA  62
            YD   IE KWQ FW +++ FK+  D +K K+Y LDMFPYPSGAGLHVGH  GYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRAQGFSVLHPMGWDSFGLPAEQYAIRTGTHPRETTEKNIANFKKQLTAMGFSYDESR  122
            R+KRAQG +VLHPMGWD+FGLPAEQYA+ TG +P E T  NIANFK+Q+ A+GFSYD  R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EFATSDPEYYKWTQKLFLILYEKGLAYMADMAVNYCPELGTVLSNEEI-ENGFSVDGGYP  181
            E  T+DP+YYKWTQ +F  LYEKGLAY A+++VN   ELGT ++NEE+  +G S  GGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRMLRQWVLRITAFADQLLEGLDELDWPESVKQLQKNWIGKSSGASVNFATEHGVIE-  240
            V R+ +RQW+L+ITA+A++LLE+L+E+DWPES+K++Q+NWIGKS+GA+V F   +   + 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  -VFTTRPDTLIGVSFLALAPEHPLVDLLTSDEQKAVVAQYIKETQSKSERDRISEMKTKS  299
             VFTTRPDTL+G ++  LAPEH+LVD +T+ +Q   VA+Y +++  KS+  R    K K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  300  GVFTGSYAKHPVTHKLIPIWIADYVLMGFGSGAVMGVPAHDERDLLFAEQFNLPVVSVLN  359
            GV TGSYA +PV  K +P+WIADYVL ++G+GA+M+VPAHDERD  FA QFNL +++VL+
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  360  KEGVCINSCCE-GFH-----LDGLSGEEAKQYVINFLEENHLGAAKIAYKLRDWLFSRQR  413
               V   +  E G+H     LDGL    A   +++ LE + +G  +++Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  414  YWGEPIPIIHFEDGSCRPLRDYELPLLPPEIQDYRPEGVGQGPLAKVREWVQVFDTETQR  473
            YWGEPIPIIH EDG+  ++ + ELPL+ P  +D RP G G++PLA+V +W++V   +  +
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  474  AGKRETHTMPQWAGSCWYYLRFCDAHNSAAPWAKEKEQYWMPVDLYIGGAEHAVLHLLYA  533
             G+RET+TMPQWAGS WYYLR+ D+HN+      E  + W+PVD+Y+GGAEHAVLHLLYA
Sbjct  484  -GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  534  RFWHQVFYEAGIVSTPEPFKKLVNQGLVLATSYRIPGKGYIYPE-IAKEENGKWVAPSGE  592
            RFWH+V+Y+ G+V+T EPF+KL NQG++L+TSYR +  + +  + + K + +     +GE
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  593  ELDVRQEKMSKSKLNGVDPQILIDEFGADAVRMYAMFSGPLDKNKLWSNQGVAGCRRFLN  652
            EL+    KMSKS  N V+P+ +++++GAD++R+Y MF GPLD +  WS++G+ G R+FL+
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  653  RFYEMVSSDRVKEDNNFEGLSLAHKLVQRVTDAIEKLSLNTIPSSFMEFINDFVK----L  708
            R Y ++++  + E+N+     + +  V+ VT+ ++++ +NT  + +M F+N   K    +
Sbjct  663  RVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLF  722

Query  709  AVYPKSAVEMAVRALAPIAPHISEELW-VLLGNSPGVQKSGWPSVLPEYLEGQTVTIVVQ  767
            + Y+K+ V++    +AP+APH++EELW  L +++ ++    WPS     L  + V IVVQ
Sbjct  723  SDYAKGFVQL----IAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQ  778

Query  768  VNGKLRARLDIMKDASKKEV--LALARESASKYLEGCEVKKAIFVPARLVNFVV  819
            ++GK++A+L + KD S+ E+  +ALA E     + G ++ K I VP +LVN+V+
Sbjct  779  IKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

542) EUBREC_1999 in NC_012781


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  698 bits (2640),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 418/840 (50%), Positives = 607/840 (73%), Gaps = 50/840 (5%)

Query  5    YNHKAIEKKWQEYWKEHETFKTDVWDFSKPKYYALDMFPYPSGVGLHAGHPEGYTATDIM  64
            Y+H AIE KWQ +W +++TFKT+  D SKPK+YALDMFPYPSG GLH GHPEGYTATDI+
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGT-DASKPKFYALDMFPYPSGAGLHVGHPEGYTATDIL  62

Query  65   SRMKRMQGYNVLHPMGYDSFGLPAEQYAVNTGHHPNGFTQKNIETFSKQLRELGFDYDWS  124
            SR KR QG NVLHPMG D+FGLPAEQYA++TG++P  FT  NI  F +Q+  LGF YDW 
Sbjct  63   SRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWD  122

Query  125  KMISTSDPEFYKWTQWIFKKLYEAGYAKHIDMPVNWCEELGTVLSNDEVI-DGKSERGGY  183
            + ++T+DP++YKWTQWIF KLYE G A + ++PVNW EELGT ++N+EV+ DG SERGGY
Sbjct  123  REVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGY  182

Query  184  PVVRKNMKQWVIDQPAFAEKLLEGLNEIDWPESTKEMQRNWIGKSTGVEVKFQIVGGG-E  242
            PVVRK M+QW++   A+AE+LLE+L+E+DWPES K+MQRNWIGKSTG +V F++ + + +
Sbjct  183  PVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  FSIFTTCIETIYGITFMVLAPDGDIVKGLMDRVENKEEVQAYIDETVKKSDMDRTELNKT  302
            F++FTT  +T++G T+ VLAP+  +V ++    ++ E V  Y  ++  KSD+ RT+L K 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTS-DQAEAVADYKRQASLKSDLARTDLAKE  301

Query  303  KSGCELKGLHCINPVNGKEVRMFIGDFVLASYGTGAVMAVPTHDQRDFEYAQAHDIEMIQ  362
            K+G    G   INPVNGKE+ + I+D+VLASYGTGA+MAVP+HD+RD E+A+  ++++I 
Sbjct  302  KTGV-WTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  363  VIDGADVSEHAFEKHDYLGKGCKLINSEEFTGMVVEDAKEAITAKLEKMGVAKRTVNYKF  422
            V++G++V E AF  ++        INS+ + G+    A   +   LE  GV++  V Y++
Sbjct  361  VLEGGNVEEAAFTEDGL------HINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRL  414

Query  423  REWIFARQRYWGEPVPCVYKEDGSIYFlpddelplvlpeledYKGK-NGKAPLENATEWK  481
            R+W+F+RQRYWGEP+P +  EDG+   +P+ ELPLVLP   D +    G +PL N T+W 
Sbjct  415  RDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWL  474

Query  482  QYDR-NGVKGTRETSTMPGSAGSSWYYMRYIDPHNDKEFANQELLKHWMPVDLYVGGPEH  540
            +  R +GVKG RET+TMP  AGSSWYY+RYIDPHN   +A++ELLK+W+PVD+YVGG+EH
Sbjct  475  EVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEH  534

Query  541  AVGHLMYSRIWNRFLFDQGLSPVKEPFKKLVHQGMILGSN----------GIKMGKRFPE  590
            AV HL+Y+R+W++ L+D G+ P KEPF+KL +QGMILG++            K+ KR   
Sbjct  535  AVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGS  594

Query  591  F----------------------VVNPSDVVEEYGADTLRLYEMFMGPLEVSKPWNDSNV  628
            F                      VVNP DVVE+YGADTLR+YEMFMGPL+ S +W++  +
Sbjct  595  FFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGL  654

Query  629  QGAKRFITRVWNFFTEPENIIEEDDGKLTRIYHQTVKKVTNDFEALGYNTAISQMMIFVN  688
            +G+++F+ RV  ++T  E I EE+ G L ++Y++TVK VT++ + + +NTAI+Q+M+FVN
Sbjct  655  EGSRKFLDRVYRLITTKE-ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVN  713

Query  689  EVYKAGRCPREFAEGLIKMLSCVCPHVGEEIWQRM-GHDDTIAFEPWPVYDEAKTVEDTV  747
               K ++   ++A G++++++   PH+GEE+WQ + + +++I++ PWP YDE+K VE+ V
Sbjct  714  AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDV  773

Query  748  EIAVQINGKTKGTLAIGKQDPKDEV--IAKAKDVIADKLTG-NIVKEIYVPGRIVNIVMK  804
            EI VQI+GK K+ L ++K+ +++E+  +A A++ +   ++G +I+K I VP ++VNIV+K
Sbjct  774  EIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

543) leuS in NC_021890


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  697 bits (2637),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 413/834 (50%), Positives = 600/834 (72%), Gaps = 22/834 (2%)

Query  3    YDPGLIEEKWQKFWKNEQVFKAEEDETKTKYYVLDMFPYPSGAGLHVGHLIGYTATDIVA  62
            YD   IE KWQ FW +++ FK+  D +K K+Y LDMFPYPSGAGLHVGH  GYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRAQGFSVLHPMGWDSFGLPAEQYAIRTGTHPRETTEKNIANFKKQLTAMGFSYDESR  122
            R+KRAQG +VLHPMGWD+FGLPAEQYA+ TG +P E T  NIANFK+Q+ A+GFSYD  R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EFATSDPEYYKWTQKLFLILYEKGLAYMADMAVNYCPELGTVLSNEEI-ENGFSVDGGYP  181
            E  T+DP+YYKWTQ +F  LYEKGLAY A+++VN   ELGT ++NEE+  +G S  GGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRMLRQWVLRITAFADQLLEGLDELDWPESVKQLQKNWIGKSSGASVNFATEHGAIE-  240
            V R+ +RQW+L+ITA+A++LLE+L+E+DWPES+K++Q+NWIGKS+GA+V F   +   + 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  -VFTTRPDTLIGVSFLALAPEHPLVDLLTSDEQKAVVAQYIKETQSKSERDRISEMKTKS  299
             VFTTRPDTL+G ++  LAPEH+LVD +T+ +Q   VA+Y +++  KS+  R    K K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  300  GVFTGSYAKHPVTHELIPIWIADYVLMGFGSGAVMGVPAHDERDLLFAEQFNLPVVSVLN  359
            GV TGSYA +PV    +P+WIADYVL ++G+GA+M+VPAHDERD  FA QFNL +++VL+
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  360  KEGVCINSCCE-GFH-----LDGLSGEEAKQYVINFLEENHLGAAKIAYKLRDWLFSRQR  413
               V   +  E G+H     LDGL    A   +++ LE + +G  +++Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  414  YWGEPIPIIHFEDGSCRPLRDYELPLLPPEIQDYRPEGVGQGPLAKVREWVQVFDTETQR  473
            YWGEPIPIIH EDG+  ++ + ELPL+ P  +D RP G G++PLA+V +W++V   +  +
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  474  AGKRETHTMPQWAGSCWYYLRFCDAHNSAAPWAKEKEQYWMPVDLYIGGAEHAVLHLLYA  533
             G+RET+TMPQWAGS WYYLR+ D+HN+      E  + W+PVD+Y+GGAEHAVLHLLYA
Sbjct  484  -GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  534  RFWHQVFYEAGIVSTPEPFKKLVNQGLVLATSYRIPGKGYIYPE-IAKEENGKWVAPSGE  592
            RFWH+V+Y+ G+V+T EPF+KL NQG++L+TSYR +  + +  + + K + +     +GE
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  593  ELDVRQEKMSKSKLNGVDPQILIDEFGADAVRMYAMFSGPLDKNKLWSNQGVAGCRRFLN  652
            EL+    KMSKS  N V+P+ +++++GAD++R+Y MF GPLD +  WS++G+ G R+FL+
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  653  RFYEMVSSDRVKEDNNFEGLSLAHKLVQRVTDAIEKLSLNTIPSSFMEFINDFVK----L  708
            R Y ++++  + E+N+     + +  V+ VT+ ++++ +NT  + +M F+N   K    +
Sbjct  663  RVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLF  722

Query  709  AVYPKSAVEMAVRVLAPIAPHISEELW-VLLGNSPGVQKSGWPSVLPEYLEGQTVTIVVQ  767
            + Y+K+ V++    +AP+APH++EELW  L +++ ++    WPS     L  + V IVVQ
Sbjct  723  SDYAKGFVQL----IAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQ  778

Query  768  VNGKLRARLDIMKDASKEEV--LALARESASKYLEGCEVKKAIFVPARLVNFVV  819
            ++GK++A+L + KD S+EE+  +ALA E     + G ++ K I VP +LVN+V+
Sbjct  779  IKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

544) leuS in NC_021888


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  697 bits (2637),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 413/834 (50%), Positives = 600/834 (72%), Gaps = 22/834 (2%)

Query  3    YDPGLIEEKWQKFWKNEQVFKAEEDETKTKYYVLDMFPYPSGAGLHVGHLIGYTATDIVA  62
            YD   IE KWQ FW +++ FK+  D +K K+Y LDMFPYPSGAGLHVGH  GYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRAQGFSVLHPMGWDSFGLPAEQYAIRTGTHPRETTEKNIANFKKQLTAMGFSYDESR  122
            R+KRAQG +VLHPMGWD+FGLPAEQYA+ TG +P E T  NIANFK+Q+ A+GFSYD  R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EFATSDPEYYKWTQKLFLILYEKGLAYMADMAVNYCPELGTVLSNEEI-ENGFSVDGGYP  181
            E  T+DP+YYKWTQ +F  LYEKGLAY A+++VN   ELGT ++NEE+  +G S  GGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRMLRQWVLRITAFADQLLEGLDELDWPESVKQLQKNWIGKSSGASVNFATEHGAIE-  240
            V R+ +RQW+L+ITA+A++LLE+L+E+DWPES+K++Q+NWIGKS+GA+V F   +   + 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  -VFTTRPDTLIGVSFLALAPEHPLVDLLTSDEQKAVVAQYIKETQSKSERDRISEMKTKS  299
             VFTTRPDTL+G ++  LAPEH+LVD +T+ +Q   VA+Y +++  KS+  R    K K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  300  GVFTGSYAKHPVTHELIPIWIADYVLMGFGSGAVMGVPAHDERDLLFAEQFNLPVVSVLN  359
            GV TGSYA +PV    +P+WIADYVL ++G+GA+M+VPAHDERD  FA QFNL +++VL+
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  360  KEGVCINSCCE-GFH-----LDGLSGEEAKQYVINFLEENHLGAAKIAYKLRDWLFSRQR  413
               V   +  E G+H     LDGL    A   +++ LE + +G  +++Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  414  YWGEPIPIIHFEDGSCRPLRDYELPLLPPEIQDYRPEGVGQGPLAKVREWVQVFDTETQR  473
            YWGEPIPIIH EDG+  ++ + ELPL+ P  +D RP G G++PLA+V +W++V   +  +
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  474  AGKRETHTMPQWAGSCWYYLRFCDAHNSAAPWAKEKEQYWMPVDLYIGGAEHAVLHLLYA  533
             G+RET+TMPQWAGS WYYLR+ D+HN+      E  + W+PVD+Y+GGAEHAVLHLLYA
Sbjct  484  -GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  534  RFWHQVFYEAGIVSTPEPFKKLVNQGLVLATSYRIPGKGYIYPE-IAKEENGKWVAPSGE  592
            RFWH+V+Y+ G+V+T EPF+KL NQG++L+TSYR +  + +  + + K + +     +GE
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  593  ELDVRQEKMSKSKLNGVDPQILIDEFGADAVRMYAMFSGPLDKNKLWSNQGVAGCRRFLN  652
            EL+    KMSKS  N V+P+ +++++GAD++R+Y MF GPLD +  WS++G+ G R+FL+
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  653  RFYEMVSSDRVKEDNNFEGLSLAHKLVQRVTDAIEKLSLNTIPSSFMEFINDFVK----L  708
            R Y ++++  + E+N+     + +  V+ VT+ ++++ +NT  + +M F+N   K    +
Sbjct  663  RVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLF  722

Query  709  AVYPKSAVEMAVRVLAPIAPHISEELW-VLLGNSPGVQKSGWPSVLPEYLEGQTVTIVVQ  767
            + Y+K+ V++    +AP+APH++EELW  L +++ ++    WPS     L  + V IVVQ
Sbjct  723  SDYAKGFVQL----IAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQ  778

Query  768  VNGKLRARLDIMKDASKEEV--LALARESASKYLEGCEVKKAIFVPARLVNFVV  819
            ++GK++A+L + KD S+EE+  +ALA E     + G ++ K I VP +LVN+V+
Sbjct  779  IKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

545) O175_01130 in NC_022108


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  697 bits (2635),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 413/834 (50%), Positives = 600/834 (72%), Gaps = 22/834 (2%)

Query  3    YDPGLIEEKWQKFWENEQVFKAEEDETKTKYYVLDMFPYPSGAGLHVGHLIGYTATDIVA  62
            YD   IE KWQ FW +++ FK+  D +K K+Y LDMFPYPSGAGLHVGH  GYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRAQGFSVLHPMGWDSFGLPAEQYAIRTGTHPRETTEKNIANFKKQLTAMGFSYDESR  122
            R+KRAQG +VLHPMGWD+FGLPAEQYA+ TG +P E T  NIANFK+Q+ A+GFSYD  R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EFATSDPEYYKWTQKLFLILYEKGLAYMADMAXNYCPELGTVLSNEEI-ENGFSVDGGYP  181
            E  T+DP+YYKWTQ +F  LYEKGLAY A+++ N   ELGT ++NEE+  +G S  GGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRMLRQWVLRITAFADQLLEGLDELDWPESVKQLQKNWIGKSSGASVNFATEHGVIE-  240
            V R+ +RQW+L+ITA+A++LLE+L+E+DWPES+K++Q+NWIGKS+GA+V F   +   + 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  -VFTTRPDTLIGVSFLALAPEHPLVDLLTSDEQKAVVAQYIKETQSKSERDRISEMKTKS  299
             VFTTRPDTL+G ++  LAPEH+LVD +T+ +Q   VA+Y +++  KS+  R    K K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  300  GVFTGSYAKHPVTHKLIPIWIADYVLMGFGSGAVMGVPAHDERDLLFAEQFNLPVVSVLN  359
            GV TGSYA +PV  K +P+WIADYVL ++G+GA+M+VPAHDERD  FA QFNL +++VL+
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  360  KEGVCINSCCE-GFH-----LDGLSGEEAKQYVINFLEENHLGAAKIAYKLRDWLFSRQR  413
               V   +  E G+H     LDGL    A   +++ LE + +G  +++Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  414  YWGEPIPIIHFEDGSCRPLRDYELPLLPPEIQDYRPEGVGQGPLAKVREWVQVFDTETQR  473
            YWGEPIPIIH EDG+  ++ + ELPL+ P  +D RP G G++PLA+V +W++V   +  +
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  474  AGKRETHTMPQWAGSCWYYLRFCDAHNSAAPWAKEKEQYWMPVDLYIGGAEHAVLHLLYA  533
             G+RET+TMPQWAGS WYYLR+ D+HN+      E  + W+PVD+Y+GGAEHAVLHLLYA
Sbjct  484  -GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  534  RFWHQVFYEAGIVSTPEPFKKLVNQGLVLATSYRIPGKGYIYPE-IAKEENGKWVAPSGE  592
            RFWH+V+Y+ G+V+T EPF+KL NQG++L+TSYR +  + +  + + K + +     +GE
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  593  ELDVRQEKMSKSKLNGVDPQILIDEFGADAVRMYAMFSGPLDKNKLWSNQGVAGCRRFLN  652
            EL+    KMSKS  N V+P+ +++++GAD++R+Y MF GPLD +  WS++G+ G R+FL+
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  653  RFYEMVSSDRVKEDNNFEGLSLAHKLVQRVTDAIEKLSLNTIPSSFMEFINDFVK----L  708
            R Y ++++  + E+N+     + +  V+ VT+ ++++ +NT  + +M F+N   K    +
Sbjct  663  RVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLF  722

Query  709  AVYPKSAVEMAVRALAPIAPHISEELW-VLLGNSPGVQKSGWPSVLPEYLEGQTVTIVVQ  767
            + Y+K+ V++    +AP+APH++EELW  L +++ ++    WPS     L  + V IVVQ
Sbjct  723  SDYAKGFVQL----IAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQ  778

Query  768  VNGKLRARLDIMKDASKEEV--LALARESASKYLEGCEVKKAIFVPARLVNFVV  819
            ++GK++A+L + KD S+EE+  +ALA E     + G ++ K I VP +LVN+V+
Sbjct  779  IKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

546) leuS in NC_010163


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  696 bits (2633),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 445/819 (55%), Positives = 590/819 (73%), Gaps = 46/819 (5%)

Query  4    YEHRKIEEKWQKHWLDNKLFKTKNDRFHQKYYVLDMFPYPSASGLHVGHIEGYTATDIVS  63
            Y+H  IE KWQ  W DN  FKT  D    K+Y LDMFPYPS++GLHVGH EGYTATDI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RFKRMQGYNVLHPMGWDAYGLPSEQYALATGKDPKSFTYQNISNFKRQIIEMGKGVDWDK  123
            RFKR QG NVLHPMGWDA+GLP+EQYA+ TG+DP  FT +NI+NFKRQI  +G + DWD+
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATTDPEYFKWTQWIFKRLYEKGLAVLKDVEVNWCEGLGTVLANDEIEIINGQMVSERG  183
            E+ TTDP+Y+KWTQWIF +LYEKGLA   +V VNW E LGT +AN+E+ + +G   SERG
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEV-LPDG--TSERG  180

Query  184  HYPVIKKPMRQWVLRITEYadrllddlalvdWPENLKEMQRNWIGKSSGAVIEFEVASTD  243
             YPV++KPMRQW+L+IT YA+RLL+DL  VDWPE++K+MQRNWIGKS+GA + F V  TD
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  244  YKFEIFTTRPDTIYGVTYCVLSPEHPLVEKIVTQDEEKDVLRYIEQTKMKSDLDRIA-DK  302
              F +FTTRPDT++G TY VL+PEH+LV+ I T D+   V  Y  Q+ +KSDL R    K
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  303  SKTGVFTGAFAKHPLTNQLIPIWIGDYVLPQYGMGAVMAVPAHDDRDYEFAMQYGLNIIE  362
             KTGV TG++A +P+  + +P+WI+DYVL+ YG GA+MAVPAHD+RD EFA Q+ L+II 
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  363  VIKGGS--EGAYTGDGIHHHSGIIDGLYNEEAIEKITKHLEDRKKGYKHYTYKLRDWVFS  420
            V+ GG+  E+A+T DG+H +S+++DGL +  AI K+   LE    G  + TY+LRDW+FS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  421  RQRYWGEPFPVIYDEDGQIHlvpddelplelpyleFIKPSGTGESPLANARDWLYVDI-N  479
            RQRYWGEP+P+I  EDG    VP+ ELPL LP    I+PSGTGESPLAN  DWL V   +
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  480  GKKGRRDTNTMPQLAGSSWYYIGYILKSNLGYIPLDSKEAKAVLDQFLPVDLYVGGTEHA  539
            G KGRR+TNTMPQ AGSSWYY+ YI   N      +      +L Q LPVD+YVGG+EHA
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHN-----TEKLADEELLKQWLPVDIYVGGAEHA  535

Query  540  VGHLLYARFWHKFFYDLGFVSSKEPFMKLVNQGMILGAD---------------------  578
            V HLLYARFWHK +YDLG V++KEPF KL NQGMILG+                      
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSF  595

Query  579  ------------HSKMSKSKGNSVSPDDFIQSHGADALRLFEMFMGPLEAEKPWSNEGLE  626
                         +KMSKS  N V+PDD ++  GAD+LR++EMFMGPL+A  +WS+EGLE
Sbjct  596  FHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLE  655

Query  627  GAKRFLDRVWRMFDF-EITQQPVDALQTVYHQTVKKVTEDYEKLAFNTAISQMMIFVNEV  685
            G+++FLDRV R++   EIT++  +AL+ VY++TVK VTE+ +++ FNTAI+Q+M+FVN  
Sbjct  656  GSRKFLDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAA  715

Query  686  YKTKVIGAAQARGFLKLLNPIAPHLTEEINETVLKHHEDLVYSEWPTYDESFLIETEVEV  745
             K   + +  A+GF++L+ P+APHL EE+ +++    E + Y  WP+YDES L+E +VE+
Sbjct  716  NKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEI  775

Query  746  AIQVNGKLRGRLQVKKDMVEEDLKKLALEHENVIKHVEG  784
             +Q++GK++++L V KD+  E+L+ +AL +E+V  ++ G
Sbjct  776  VVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAG  814

547) CCU_12230 in NC_021018


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  696 bits (2633),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 425/839 (51%), Positives = 583/839 (70%), Gaps = 47/839 (5%)

Query  5    YNHKVVEGKWQKVWDDNKAFAATDDYSKPKYYALVEFPYPSGQGLHVGHPRPYTALDIVA  64
            Y+H  +E KWQ  W DN +F +  D SKPK+YAL  FPYPSG GLHVGHP  YTA DI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  65   RKRRMQGYNVLYPMGWDAFGLPTENYAIKNKIHPKEVTKTNVARFKKQLHSLGYSFDWDR  124
            R +R QG NVL PMGWDAFGLP+E+YA+    +P E T  N+A FK+Q+++LG+S+DWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  125  EINTTDPEYYKWTQWIFLKLFKAGLAYKKEMPINWCTSCKVGLANEEVV-NGVCERCGSE  183
            E+NTTDP+YYKWTQWIF KL+  GLAY  E+P+NW      ++ANEEV+ +G  ER G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  184  VVRKVKSEWMLKITDYADKLIEGLDGVDYIERVKVSQKNWIGRSTGAEVDFSVKGKEDKL  243
            VVRK   +WMLKIT YA++L+E+L+ VD  E +K  Q+NWIG+STGA+V F VK+ +  +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  244  RIYTTRCDTLFGVTYMVVSPEHPILDKYKDEIGNWSDIEAYREQAAKKSDFERSELAKDK  303
             ++TTR DTLFG TY V++PEH+++D           +  Y+ QA+ KSD+ R++LAK+K
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQA-EAVADYKRQASLKSDLARTDLAKEK  302

Query  304  TGVCIDGLTAINPVNGKEIPIYVSDYVLMSYGTGAIMAVPAHDDRDWEFAKKFGLPLIQV  363
            TGV  ++  AINPVNGKE+P+ ++DYVL SYGTGAIMAVPAHD+RDWEFAK+F L +I V
Sbjct  303  TGVWTGSY-AINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  364  VAKDGEEVDINETAFTDVATGVLINSDFLNGLEVKDAKEKMIKFLEEKGIGQAKTNYKLR  423
            +    E  +++E+AFT+   G+ INSDFL+GL+   A  KM+  LE  G+G+ +  Y+LR
Sbjct  362  L----EGGNVEEAAFTE--DGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  424  DWVFSRQRYWGEPIPIVHCDKCGYVPIDESQLPLLLPEVDSYMPTDNGESPLAAMTDWVN  483
            DW+FSRQRYWGEPIPI+H +     ++ ES+LPL+LP      P++ GESPLA +TDW++
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  484  TTCPCCGGPAKRETDTMPQWAGSSWYFLRYTDPHNTEALASKEALKYWLPVDWYNGGMEH  543
             T    G  ++RET+TMPQWAGSSWY+LRY DPHNTE LA  E LK WLPVD Y GG EH
Sbjct  476  VTRE-DGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEH  534

Query  544  TTLHLLYSRFWHKFLYDQGVVPTPEPYQKRTSHGMILG----------------------  581
            + LHLLY+RFWHK LYD GVVPT EP+QK  ++GMILG                      
Sbjct  535  AVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGS  594

Query  582  -----------ENGEKMSKSRGNVVNPDDIVDVYGADTLRTYEMFIGAFDLAASWSEDGV  630
                       +   KMSKS  NVVNPDD+V+ YGADTLR YEMF+G++D + +WSE+G+
Sbjct  595  FFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGL  654

Query  631  KGCRRFLDRVWKLQDSVTDEKGYSKDMETKMHQVIKKVSNDFENLKYNTAIAAMMALLND  690
             G R+FLDRV +L  +       S  ++   ++ +K V+++ +++K+NTAIA +M ++N 
Sbjct  655  EGSRKFLDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNA  714

Query  691  FYKKGSVTADEFKTLLILLNPVAPHITEELW-SVKNYGGYVYQQTWPEFDEAKTVESTVE  749
              K + + +D  K ++ L+ P APH+ EELW ++   G  +    WP +DE+K VE+ VE
Sbjct  715  ANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVE  774

Query  750  IAVQINGKTKATLAIGKEDPKDEV--IAKAKEVIADKLTG-NVIKEIYVPGRIVNIVMK  805
            I VQI+GK KA L ++K+ +++E+  +A A+E +   ++G ++IK I VP ++VNIV+K
Sbjct  775  IVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

548) leuS in NC_009922


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  696 bits (2633),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 414/838 (50%), Positives = 587/838 (71%), Gaps = 41/838 (4%)

Query  1    MKQYNPKEIESKWQNIWEERGVFHASNDKDKEKFYALIEFPYPSGQGLHVGHPRPYTALD  60
            M  Y+   IE+KWQ +W +   F ++ D  K KFYAL  FPYPSG GLHVGHP  YTA D
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   VVSRKRRLEGYNVLYPMGWDAFGLPTENYAIKNKIHPKVVTEQNVARFKKQLQGLGMSFD  120
            ++SR +R +G NVL PMGWDAFGLP+E+YA+    +P   T +N+A FK+Q+++LG S+D
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WSREINTTDPEYYKWTQWIFLKLFEKGLAYKKEMSINWCTSCKVGLANEEVV-NGGCERC  179
            W RE+NTTDP+YYKWTQWIF KL+EKGLAY  E+++NW      ++ANEEV+ +G  ER 
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  180  GAEVVRKQKNQWMLKITEYAERLINDLDLVDYIERVKIQQKNWIGKSEGMEVDFEITG-G  238
            G  VVRK   QWMLKIT YAERL++DL+ VD  E +K  Q+NWIGKS G +V F + + +
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  239  KKITVYTTRPDTLFGSTYMVISPEHPYIEELAAHIQNMDDLVHYREEAAKKSEFERTELV  298
            K +TV+TTRPDTLFG+TY V++PEH+ ++ +++  Q  + + +Y+ +A+ KS++ RT+L 
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQA-EAVADYKRQASLKSDLARTDLA  299

Query  299  KDKTGVKIEGIEATNPATGKQIPIFISDYVMMSYGTGAIMAVPGHDTRDWEFAKKFNLPI  358
            K+KTGV   +  A NP  GK++P+ I+DYV+ SYGTGAIMAVP+HD RDWEFAK+FNL I
Sbjct  300  KEKTGVWTGSY-AINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDI  358

Query  359  VEVVSGGNVDEAAYTDTEEGIIVNSDFINGMQVKEAKEKISSWLEEKGLGKRKVNYKLRD  418
            + V+ GGNV+EAA+  TE+G+ +NSDF++G++   A  K+  WLE  G+G+ +V Y+LRD
Sbjct  359  IPVLEGGNVEEAAF--TEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  419  WVFSRQRYWGEPIPLVHCDCCGWVPVPESQLPVLLPEVESYEPTDNGESPLANLRDWVET  478
            W+FSRQRYWGEPIP++H +     +VPES+LP++LP      P++ GESPLAN+ DW+E 
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  479  TCPKCGGKAERETDTMPQWAGSSWYFLRYTDPHNNEELASKENLDYWMPIDWYNGGMEHT  538
            T    G K+ RET+TMPQWAGSSWY+LRY DPHN E LA  E L  W+P+D Y GG EH+
Sbjct  477  TRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  539  TLHLLYSRFWHKFLYDCGVVPSCEPYQKRTSHGMILG-----------------------  575
             LHLLY+RFWHK LYD GVVP+ EP+QK  ++GMILG                       
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSF  595

Query  576  ----------ENNEKMSKSRGNVINPDDIVTEFGADTLRLYEMFIGDFEKSVPWSQNGVK  625
                      +   KMSKS  NV+NPDD+V ++GADTLR+YEMF+G ++ S++WS++G+ 
Sbjct  596  FHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLE  655

Query  626  GCRRFLDRIWKLQEILVDSQEMTKELEGNIHKTIKKVTEDYETLKFNTAVASMMALINDF  685
            G R+FLDR+ +L      ++E +  L+   + T+K VTE+ + +KFNTA+A +M ++N  
Sbjct  656  GSRKFLDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAA  715

Query  686  YDHGTVTKGDMKTLLTLLNPVAPHITEELWEVLGFEGHIYG-TTWPIWDEAKTIDSVVEI  744
              ++ +  +  K ++ L+ P APH+ EELW+ L   G+  +   WP  DE+K +++ VEI
Sbjct  716  NKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEI  775

Query  745  PIQINGKVKGQMVISVDFTADQVKEQFRNDERLMALVEGKSIVKEIYVPGKIYNIVVK  802
             +QI+GKVK+++V++ D++ ++++E    +E++ A + GK I+K I VP K+ NIV+K
Sbjct  776  VVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

549) Rumal_3096 in NC_014833


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  695 bits (2629),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 430/850 (51%), Positives = 601/850 (71%), Gaps = 56/850 (6%)

Query  1    MKNYDFSAIEKKWQKYWEEHETFKTDVWDFSKPKFYALDMFPYPSGVGLHAGHPEGYTAT  60
            M  YD +AIE KWQ +W +++TFKT+  D SKPKFYALDMFPYPSG GLH GHPEGYTAT
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGT-DASKPKFYALDMFPYPSGAGLHVGHPEGYTAT  59

Query  61   DIVSRMKRMQGFNVLHPMGYDSFGLPAEQYAVNTGNHPNGFTQENIKTFSKQLKELGFDY  120
            DI+SR KR QG NVLHPMG D+FGLPAEQYA++TGN+P  FT ENI  F +Q++ LGF Y
Sbjct  60   DILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSY  119

Query  121  DWSKMLATSDPSFYKWTQWIFKQLYLDGYAKYIDMPVNWCEELGTVLSNDEVI-DGKSER  179
            DW + + T+DP++YKWTQWIF +LY  G A   ++PVNW EELGT ++N+EV+ DG SER
Sbjct  120  DWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSER  179

Query  180  GGFPVVRKNMKQWVIDQPAFAEKLLEGLDEIDWPESTKSMQRNWIGKSTGVEVEFDIVGG  239
            GG+PVVRK M+QW++   A+AE+LLE+L+E+DWPES K MQRNWIGKSTG +V F + + 
Sbjct  180  GGYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDT  239

Query  240  GK-FSIFTTCIETIYGITFMVLAPDGEITERLLDRVQNREEVQAYIDETKKKNDMDRTEL  298
            +K F++FTT  +T++G T+ VLAP+  + + +    Q  E V  Y  ++  K+D+ RT+L
Sbjct  240  DKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQA-EAVADYKRQASLKSDLARTDL  298

Query  299  NKTKSGCELKGVTCINPVNGKEVRMFIGDFVLASYGTGAVMAVPSHDQRDFEYAIAHNID  358
             K K+G    G   INPVNGKE+ + I+D+VLASYGTGA+MAVP+HD+RD E+A   N+D
Sbjct  299  AKEKTGV-WTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLD  357

Query  359  MIQVIDGDEKLGHVDVSKQAFEKQGYLGKGYKLINSEEFTGLTVEEAKEAITVKLEKMGR  418
            +I V++G+      +V   AF  +G        INS+ + GL    A   +   LE  G 
Sbjct  358  IIPVLEGG------NVEEAAFTEDGL------HINSDFLDGLDKASAIAKMVEWLEAEGV  405

Query  419  AKRTVNYHFREWIFARQRYWGEPVPVVHTENGIHvlddee--lplvlpelddYKGKNGKA  476
            ++  V Y++R+W+F+RQRYWGEP+P++H E+G      E     ++    D   +  G +
Sbjct  406  GNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGES  465

Query  477  PLENATEWKQYDH-NGVKGVRETSTMPGSAGSSWYFLRYIDPNNDKQFADPELLKHWMPV  535
            PL N T+W +  + +GVKG RET+TMP  AGSSWY+LRYIDP+N  ++AD ELLK+W+PV
Sbjct  466  PLANVTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPV  525

Query  536  DLYIGGPEHTVGHLIYSRIWNRYLYDKGLAPTKEPFKKLVHQGMILG-------------  582
            D+Y+GG+EH+V HL+Y+R+W++ LYD G+ PTKEPF+KL +QGMILG             
Sbjct  526  DIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVAT  585

Query  583  --------------------ENGIKMGKRFPKYVVNPSDIIRDYGADTLRLYEMFMGPLE  622
                                +   KM+K + K VVNP D++ +YGADTLR+YEMFMGPL+
Sbjct  586  DKVEKRDGSFFHVETGEELEQAPAKMSKSL-KNVVNPDDVVEQYGADTLRVYEMFMGPLD  644

Query  623  VSKPWSPSGVEGAKKFLNRVWVFFTDENNLTADNDGALTKVYHQTVKKVTDDFETLAFNT  682
             S +WS  G+EG++KFL+RV  ++T  +++T +N GAL KVY++TVK VT++ + + FNT
Sbjct  645  ASIAWSEEGLEGSRKFLDRVYRLITT-KEITEENSGALDKVYNETVKAVTEQVDQMKFNT  703

Query  683  AIAQMMIFVNAVYKNGSCPKEYAEGLIKMLSCIAPHIGEEIWSIL-GHDDTIAYEKWPVY  741
            AIAQ+M+FVNA  K++    +YA G++++++ +APH+GEE+W  L + +++I+Y  WP Y
Sbjct  704  AIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSY  763

Query  742  DEAQLVEDTVEIVVQVNGKIKTKLNIAKDEDKESVLAKAKADENVAKVIDGKNVVKEIVV  801
            DE++LVE+ VEIVVQ++GK+K+KL +AKD  +E +   A A+E+V   I GK+++K I V
Sbjct  764  DESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAV  823

Query  802  PNKLVNIVVK  811
            PNKLVNIV+K
Sbjct  824  PNKLVNIVIK  833

550) leuS in NC_016798


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  695 bits (2627),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 411/834 (50%), Positives = 599/834 (72%), Gaps = 22/834 (2%)

Query  3    YDPGLIEEKWQKFWENEQVFKAEEDETKTKYYVLDMFPYPSGAGLHVGHLIGYTATDIVA  62
            YD   IE KWQ FW +++ FK+  D +K K+Y LDMFPYPSGAGLHVGH  GYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRAQGFSVLHPMGWDSFGLPAEQYAIRTGTHPRETTEKNIANFKKQLTAMGFSYDESR  122
            R+KRAQG +VLHPMGWD+FGLPAEQYA+ TG +P E T  NIANFK+Q+ A+GFSYD  R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EFATSDPEYYKWTQKLFLILYEKGLAYMADMAVNYCPELGTVLSNEEI-ENGFSVDGGYP  181
            E  T+DP+YYKWTQ +F  LYEKGLAY A+++VN   ELGT ++NEE+  +G S  GGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRMLRQWVLRITAFADQLLEGLDELDWPESVKQLQKNWIGKSSGASVNFATEHGVIE-  240
            V R+ +RQW+L+ITA+A++LLE+L+E+DWPES+K++Q+NWIGKS+GA+V F   +   + 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  -VFTTRPDTLIGVSFLALAPEHPLVDLLTSDEQKAVVAQYIKETQSKSERDRISEMKTKS  299
             VFTTRPDTL+G ++  LAPEH+LVD +T+ +Q   VA+Y +++  KS+  R    K K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  300  GVFTGSYAKHPVTHELIPIWIADYVLMGFGSGAVMGVPAHDERDLLFAEQFNLPVVSVLN  359
            GV TGSYA +PV    +P+WIADYVL ++G+GA+M+VPAHDERD  FA QFNL +++VL+
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  360  KEGVCINSCCE-GFH-----LDGLSGEEAKQYVINFLEENHLGAAKIAYKLRDWLFSRQR  413
               V   +  E G+H     LDGL    A   +++ LE + +G  +++Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  414  YWGEPIPIIHFEDGSCRPLRDYELPLLPPEIQDYRPEGVGQGPLAKVREWVQVFDTETQR  473
            YWGEPIPIIH EDG+  ++ + ELPL+ P  +D RP G G++PLA+V +W++V   +  +
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  474  AGKRETHTMPQWAGSCWYYLRFCDAHNSAAPWAKEKEQYWMPVDLYIGGAEHAVLHLLYA  533
             G+RET+TMPQWAGS WYYLR+ D+HN+      E  + W+PVD+Y+GGAEHAVLHLLYA
Sbjct  484  -GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  534  RFWHQIFYEAGIVSTPEPFKKLVNQGLVLATSYRIPGKGYIYPE-IAKEENGKWVAPSGE  592
            RFWH+++Y+ G+V+T EPF+KL NQG++L+TSYR +  + +  + + K + +     +GE
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  593  ELDVRQEKMSKSKLNGVDPQILIDEFGADAVRMYAMFSGPLDKNKLWSNQGVAGCRRFLN  652
            EL+    KMSKS  N V+P+ +++++GAD++R+Y MF GPLD +  WS++G+ G R+FL+
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  653  RFYEMVSSDRVKEDNNFEGLSLAHKLVQRVTDAIEKLSLNTIPSSFMEFINDFVK----L  708
            R Y ++++  + E+N+     + +  V+ VT+ ++++ +NT  + +M F+N   K    +
Sbjct  663  RVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLF  722

Query  709  AVYPKSAVEMAVRALAPIAPHISEELW-VLLGNSPGVQKSGWPSVLPEYLEGQTVTIVVQ  767
            + Y+K+ V++    +AP+APH++EELW  L +++ ++    WPS     L  + V IVVQ
Sbjct  723  SDYAKGFVQL----IAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQ  778

Query  768  VNGKLRARLDIMKDASKEEV--LALARESASKYLEGCEVKEAIFVPARLVNFVV  819
            ++GK++A+L + KD S+EE+  +ALA E     + G ++   I VP +LVN+V+
Sbjct  779  IKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

551) CTO_0229 in NC_017437


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  695 bits (2627),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 411/834 (50%), Positives = 599/834 (72%), Gaps = 22/834 (2%)

Query  3    YDPGLIEEKWQKFWENEQVFKAEEDETKTKYYVLDMFPYPSGAGLHVGHLIGYTATDIVA  62
            YD   IE KWQ FW +++ FK+  D +K K+Y LDMFPYPSGAGLHVGH  GYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRAQGFSVLHPMGWDSFGLPAEQYAIRTGTHPRETTEKNIANFKKQLTAMGFSYDESR  122
            R+KRAQG +VLHPMGWD+FGLPAEQYA+ TG +P E T  NIANFK+Q+ A+GFSYD  R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EFATSDPEYYKWTQKLFLILYEKGLAYMADMAVNYCPELGTVLSNEEI-ENGFSVDGGYP  181
            E  T+DP+YYKWTQ +F  LYEKGLAY A+++VN   ELGT ++NEE+  +G S  GGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRMLRQWVLRITAFADQLLEGLDELDWPESVKQLQKNWIGKSSGASVNFATEHGVIE-  240
            V R+ +RQW+L+ITA+A++LLE+L+E+DWPES+K++Q+NWIGKS+GA+V F   +   + 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  -VFTTRPDTLIGVSFLALAPEHPLVDLLTSDEQKAVVAQYIKETQSKSERDRISEMKTKS  299
             VFTTRPDTL+G ++  LAPEH+LVD +T+ +Q   VA+Y +++  KS+  R    K K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  300  GVFTGSYAKHPVTHELIPIWIADYVLMGFGSGAVMGVPAHDERDLLFAEQFNLPVVSVLN  359
            GV TGSYA +PV    +P+WIADYVL ++G+GA+M+VPAHDERD  FA QFNL +++VL+
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  360  KEGVCINSCCE-GFH-----LDGLSGEEAKQYVINFLEENHLGAAKIAYKLRDWLFSRQR  413
               V   +  E G+H     LDGL    A   +++ LE + +G  +++Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  414  YWGEPIPIIHFEDGSCRPLRDYELPLLPPEIQDYRPEGVGQGPLAKVREWVQVFDTETQR  473
            YWGEPIPIIH EDG+  ++ + ELPL+ P  +D RP G G++PLA+V +W++V   +  +
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  474  AGKRETHTMPQWAGSCWYYLRFCDAHNSAAPWAKEKEQYWMPVDLYIGGAEHAVLHLLYA  533
             G+RET+TMPQWAGS WYYLR+ D+HN+      E  + W+PVD+Y+GGAEHAVLHLLYA
Sbjct  484  -GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  534  RFWHQIFYEAGIVSTPEPFKKLVNQGLVLATSYRIPGKGYIYPE-IAKEENGKWVAPSGE  592
            RFWH+++Y+ G+V+T EPF+KL NQG++L+TSYR +  + +  + + K + +     +GE
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  593  ELDVRQEKMSKSKLNGVDPQILIDEFGADAVRMYAMFSGPLDKNKLWSNQGVAGCRRFLN  652
            EL+    KMSKS  N V+P+ +++++GAD++R+Y MF GPLD +  WS++G+ G R+FL+
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  653  RFYEMVSSDRVKEDNNFEGLSLAHKLVQRVTDAIEKLSLNTIPSSFMEFINDFVK----L  708
            R Y ++++  + E+N+     + +  V+ VT+ ++++ +NT  + +M F+N   K    +
Sbjct  663  RVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLF  722

Query  709  AVYPKSAVEMAVRALAPIAPHISEELW-VLLGNSPGVQKSGWPSVLPEYLEGQTVTIVVQ  767
            + Y+K+ V++    +AP+APH++EELW  L +++ ++    WPS     L  + V IVVQ
Sbjct  723  SDYAKGFVQL----IAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQ  778

Query  768  VNGKLRARLDIMKDASKEEV--LALARESASKYLEGCEVKEAIFVPARLVNFVV  819
            ++GK++A+L + KD S+EE+  +ALA E     + G ++   I VP +LVN+V+
Sbjct  779  IKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

552) A363_00224 in NC_020966


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  695 bits (2627),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 411/834 (50%), Positives = 599/834 (72%), Gaps = 22/834 (2%)

Query  3    YDPGLIEEKWQKFWENEQVFKAEEDETKTKYYVLDMFPYPSGAGLHVGHLIGYTATDIVA  62
            YD   IE KWQ FW +++ FK+  D +K K+Y LDMFPYPSGAGLHVGH  GYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRAQGFSVLHPMGWDSFGLPAEQYAIRTGTHPRETTEKNIANFKKQLTAMGFSYDESR  122
            R+KRAQG +VLHPMGWD+FGLPAEQYA+ TG +P E T  NIANFK+Q+ A+GFSYD  R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EFATSDPEYYKWTQKLFLILYEKGLAYMADMAVNYCPELGTVLSNEEI-ENGFSVDGGYP  181
            E  T+DP+YYKWTQ +F  LYEKGLAY A+++VN   ELGT ++NEE+  +G S  GGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRMLRQWVLRITAFADQLLEGLDELDWPESVKQLQKNWIGKSSGASVNFATEHGVIE-  240
            V R+ +RQW+L+ITA+A++LLE+L+E+DWPES+K++Q+NWIGKS+GA+V F   +   + 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  -VFTTRPDTLIGVSFLALAPEHPLVDLLTSDEQKAVVAQYIKETQSKSERDRISEMKTKS  299
             VFTTRPDTL+G ++  LAPEH+LVD +T+ +Q   VA+Y +++  KS+  R    K K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  300  GVFTGSYAKHPVTHELIPIWIADYVLMGFGSGAVMGVPAHDERDLLFAEQFNLPVVSVLN  359
            GV TGSYA +PV    +P+WIADYVL ++G+GA+M+VPAHDERD  FA QFNL +++VL+
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  360  KEGVCINSCCE-GFH-----LDGLSGEEAKQYVINFLEENHLGAAKIAYKLRDWLFSRQR  413
               V   +  E G+H     LDGL    A   +++ LE + +G  +++Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  414  YWGEPIPIIHFEDGSCRPLRDYELPLLPPEIQDYRPEGVGQGPLAKVREWVQVFDTETQR  473
            YWGEPIPIIH EDG+  ++ + ELPL+ P  +D RP G G++PLA+V +W++V   +  +
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  474  AGKRETHTMPQWAGSCWYYLRFCDAHNSAAPWAKEKEQYWMPVDLYIGGAEHAVLHLLYA  533
             G+RET+TMPQWAGS WYYLR+ D+HN+      E  + W+PVD+Y+GGAEHAVLHLLYA
Sbjct  484  -GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  534  RFWHQIFYEAGIVSTPEPFKKLVNQGLVLATSYRIPGKGYIYPE-IAKEENGKWVAPSGE  592
            RFWH+++Y+ G+V+T EPF+KL NQG++L+TSYR +  + +  + + K + +     +GE
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  593  ELDVRQEKMSKSKLNGVDPQILIDEFGADAVRMYAMFSGPLDKNKLWSNQGVAGCRRFLN  652
            EL+    KMSKS  N V+P+ +++++GAD++R+Y MF GPLD +  WS++G+ G R+FL+
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  653  RFYEMVSSDRVKEDNNFEGLSLAHKLVQRVTDAIEKLSLNTIPSSFMEFINDFVK----L  708
            R Y ++++  + E+N+     + +  V+ VT+ ++++ +NT  + +M F+N   K    +
Sbjct  663  RVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLF  722

Query  709  AVYPKSAVEMAVRALAPIAPHISEELW-VLLGNSPGVQKSGWPSVLPEYLEGQTVTIVVQ  767
            + Y+K+ V++    +AP+APH++EELW  L +++ ++    WPS     L  + V IVVQ
Sbjct  723  SDYAKGFVQL----IAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQ  778

Query  768  VNGKLRARLDIMKDASKEEV--LALARESASKYLEGCEVKEAIFVPARLVNFVV  819
            ++GK++A+L + KD S+EE+  +ALA E     + G ++   I VP +LVN+V+
Sbjct  779  IKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

553) A5291_00223 in NC_020939


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  695 bits (2627),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 411/834 (50%), Positives = 599/834 (72%), Gaps = 22/834 (2%)

Query  3    YDPGLIEEKWQKFWENEQVFKAEEDETKTKYYVLDMFPYPSGAGLHVGHLIGYTATDIVA  62
            YD   IE KWQ FW +++ FK+  D +K K+Y LDMFPYPSGAGLHVGH  GYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRAQGFSVLHPMGWDSFGLPAEQYAIRTGTHPRETTEKNIANFKKQLTAMGFSYDESR  122
            R+KRAQG +VLHPMGWD+FGLPAEQYA+ TG +P E T  NIANFK+Q+ A+GFSYD  R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EFATSDPEYYKWTQKLFLILYEKGLAYMADMAVNYCPELGTVLSNEEI-ENGFSVDGGYP  181
            E  T+DP+YYKWTQ +F  LYEKGLAY A+++VN   ELGT ++NEE+  +G S  GGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRMLRQWVLRITAFADQLLEGLDELDWPESVKQLQKNWIGKSSGASVNFATEHGVIE-  240
            V R+ +RQW+L+ITA+A++LLE+L+E+DWPES+K++Q+NWIGKS+GA+V F   +   + 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  -VFTTRPDTLIGVSFLALAPEHPLVDLLTSDEQKAVVAQYIKETQSKSERDRISEMKTKS  299
             VFTTRPDTL+G ++  LAPEH+LVD +T+ +Q   VA+Y +++  KS+  R    K K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  300  GVFTGSYAKHPVTHELIPIWIADYVLMGFGSGAVMGVPAHDERDLLFAEQFNLPVVSVLN  359
            GV TGSYA +PV    +P+WIADYVL ++G+GA+M+VPAHDERD  FA QFNL +++VL+
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  360  KEGVCINSCCE-GFH-----LDGLSGEEAKQYVINFLEENHLGAAKIAYKLRDWLFSRQR  413
               V   +  E G+H     LDGL    A   +++ LE + +G  +++Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  414  YWGEPIPIIHFEDGSCRPLRDYELPLLPPEIQDYRPEGVGQGPLAKVREWVQVFDTETQR  473
            YWGEPIPIIH EDG+  ++ + ELPL+ P  +D RP G G++PLA+V +W++V   +  +
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  474  AGKRETHTMPQWAGSCWYYLRFCDAHNSAAPWAKEKEQYWMPVDLYIGGAEHAVLHLLYA  533
             G+RET+TMPQWAGS WYYLR+ D+HN+      E  + W+PVD+Y+GGAEHAVLHLLYA
Sbjct  484  -GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  534  RFWHQIFYEAGIVSTPEPFKKLVNQGLVLATSYRIPGKGYIYPE-IAKEENGKWVAPSGE  592
            RFWH+++Y+ G+V+T EPF+KL NQG++L+TSYR +  + +  + + K + +     +GE
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  593  ELDVRQEKMSKSKLNGVDPQILIDEFGADAVRMYAMFSGPLDKNKLWSNQGVAGCRRFLN  652
            EL+    KMSKS  N V+P+ +++++GAD++R+Y MF GPLD +  WS++G+ G R+FL+
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  653  RFYEMVSSDRVKEDNNFEGLSLAHKLVQRVTDAIEKLSLNTIPSSFMEFINDFVK----L  708
            R Y ++++  + E+N+     + +  V+ VT+ ++++ +NT  + +M F+N   K    +
Sbjct  663  RVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLF  722

Query  709  AVYPKSAVEMAVRALAPIAPHISEELW-VLLGNSPGVQKSGWPSVLPEYLEGQTVTIVVQ  767
            + Y+K+ V++    +AP+APH++EELW  L +++ ++    WPS     L  + V IVVQ
Sbjct  723  SDYAKGFVQL----IAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQ  778

Query  768  VNGKLRARLDIMKDASKEEV--LALARESASKYLEGCEVKEAIFVPARLVNFVV  819
            ++GK++A+L + KD S+EE+  +ALA E     + G ++   I VP +LVN+V+
Sbjct  779  IKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

554) leuS in NC_007429


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  695 bits (2630),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 411/834 (50%), Positives = 599/834 (72%), Gaps = 22/834 (2%)

Query  3    YDPGLIEEKWQKFWKNEQVFKAEEDETKTKYYVLDMFPYPSGAGLHVGHLIGYTATDIVA  62
            YD   IE KWQ FW +++ FK+  D +K K+Y LDMFPYPSGAGLHVGH  GYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRAQGFSVLHPMGWDSFGLPAEQYAIRTGTHPRETTEKNIANFKKQLTAMGFSYDESR  122
            R+KRAQG +VLHPMGWD+FGLPAEQYA+ TG +P E T  NIANFK+Q+ A+GFSYD  R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EFATSDPEYYKWTQKLFLILYEKGLAYMADMAVNYCPELGTVLSNEEI-ENGFSVDGGYP  181
            E  T+DP+YYKWTQ +F  LYEKGLAY A+++VN   ELGT ++NEE+  +G S  GGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRMLRQWVLRITAFADQLLEGLDELDWPESVKQLQKNWIGKSSGASVNFATEHGAIE-  240
            V R+ +RQW+L+ITA+A++LLE+L+E+DWPES+K++Q+NWIGKS+GA+V F   +   + 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  -VFTTRPDTLIGVSFLALAPEHPLVDLLTSDEQKAVVAQYIKETQSKSERDRISEMKTKS  299
             VFTTRPDTL+G ++  LAPEH+LVD +T+ +Q   VA+Y +++  KS+  R    K K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  300  GVFTGSYAKHPVTHELIPIWIADYVLIGFGSGAVMGVPAHDERDLLFAEQFNLPVVSVLN  359
            GV TGSYA +PV    +P+WIADYVL ++G+GA+M+VPAHDERD  FA QFNL +++VL+
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  360  KEGVCINSCCE-GFH-----LDGLSGEEAKQYVINFLEENHLGAAKIAYKLRDWLFSRQR  413
               V   +  E G+H     LDGL    A   +++ LE + +G  +++Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  414  YWGEPIPIIHFEDGSCRPLRDYELPLLPPEIQDYRPEGVGQGPLAKVREWVQVFDTETQR  473
            YWGEPIPIIH EDG+  ++ + ELPL+ P  +D RP G G++PLA+V +W++V   +  +
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  474  AGKRETHTMPQWAGSCWYYLRFCDAHNSAAPWAKEKEQYWMPVDLYIGGAEHAVLHLLYA  533
             G+RET+TMPQWAGS WYYLR+ D+HN+      E  + W+PVD+Y+GGAEHAVLHLLYA
Sbjct  484  -GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  534  RFWHQIFYEAGIVSTPEPFKKLVNQGLVLATSYRIPGKGYIYPE-IAKEENGKWVAPSGE  592
            RFWH+++Y+ G+V+T EPF+KL NQG++L+TSYR +  + +  + + K + +     +GE
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  593  ELDVRQEKMSKSKLNGVDPQILIDEFGADAVRMYAMFSGPLDKNKLWSNQGVAGCRRFLN  652
            EL+    KMSKS  N V+P+ +++++GAD++R+Y MF GPLD +  WS++G+ G R+FL+
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  653  RFYEMVSSDRVKEDNNFEGLSLAHKLVQRVTDAIEKLSLNTIPSSFMEFINDFVK----L  708
            R Y ++++  + E+N+     + +  V+ VT+ ++++ +NT  + +M F+N   K    +
Sbjct  663  RVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLF  722

Query  709  AVYPKSAVEMAVRALAPIAPHISEELW-VLLGNSPGVQKSGWPSVLPEYLEGQTVTIVVQ  767
            + Y+K+ V++    +AP+APH++EELW  L +++ ++    WPS     L  + V IVVQ
Sbjct  723  SDYAKGFVQL----IAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQ  778

Query  768  VNGKLRARLDIMKDASKEEV--LALARESASKYLEGCEVKEAIFVPARLVNFVV  819
            ++GK++A+L + KD S+EE+  +ALA E     + G ++   I VP +LVN+V+
Sbjct  779  IKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

555) leuS in NC_012686


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  695 bits (2630),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 411/834 (50%), Positives = 599/834 (72%), Gaps = 22/834 (2%)

Query  3    YDPGLIEEKWQKFWKNEQVFKAEEDETKTKYYVLDMFPYPSGAGLHVGHLIGYTATDIVA  62
            YD   IE KWQ FW +++ FK+  D +K K+Y LDMFPYPSGAGLHVGH  GYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRAQGFSVLHPMGWDSFGLPAEQYAIRTGTHPRETTEKNIANFKKQLTAMGFSYDESR  122
            R+KRAQG +VLHPMGWD+FGLPAEQYA+ TG +P E T  NIANFK+Q+ A+GFSYD  R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EFATSDPEYYKWTQKLFLILYEKGLAYMADMAVNYCPELGTVLSNEEI-ENGFSVDGGYP  181
            E  T+DP+YYKWTQ +F  LYEKGLAY A+++VN   ELGT ++NEE+  +G S  GGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRMLRQWVLRITAFADQLLEGLDELDWPESVKQLQKNWIGKSSGASVNFATEHGAIE-  240
            V R+ +RQW+L+ITA+A++LLE+L+E+DWPES+K++Q+NWIGKS+GA+V F   +   + 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  -VFTTRPDTLIGVSFLALAPEHPLVDLLTSDEQKAVVAQYIKETQSKSERDRISEMKTKS  299
             VFTTRPDTL+G ++  LAPEH+LVD +T+ +Q   VA+Y +++  KS+  R    K K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  300  GVFTGSYAKHPVTHELIPIWIADYVLIGFGSGAVMGVPAHDERDLLFAEQFNLPVVSVLN  359
            GV TGSYA +PV    +P+WIADYVL ++G+GA+M+VPAHDERD  FA QFNL +++VL+
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  360  KEGVCINSCCE-GFH-----LDGLSGEEAKQYVINFLEENHLGAAKIAYKLRDWLFSRQR  413
               V   +  E G+H     LDGL    A   +++ LE + +G  +++Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  414  YWGEPIPIIHFEDGSCRPLRDYELPLLPPEIQDYRPEGVGQGPLAKVREWVQVFDTETQR  473
            YWGEPIPIIH EDG+  ++ + ELPL+ P  +D RP G G++PLA+V +W++V   +  +
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  474  AGKRETHTMPQWAGSCWYYLRFCDAHNSAAPWAKEKEQYWMPVDLYIGGAEHAVLHLLYA  533
             G+RET+TMPQWAGS WYYLR+ D+HN+      E  + W+PVD+Y+GGAEHAVLHLLYA
Sbjct  484  -GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  534  RFWHQIFYEAGIVSTPEPFKKLVNQGLVLATSYRIPGKGYIYPE-IAKEENGKWVAPSGE  592
            RFWH+++Y+ G+V+T EPF+KL NQG++L+TSYR +  + +  + + K + +     +GE
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  593  ELDVRQEKMSKSKLNGVDPQILIDEFGADAVRMYAMFSGPLDKNKLWSNQGVAGCRRFLN  652
            EL+    KMSKS  N V+P+ +++++GAD++R+Y MF GPLD +  WS++G+ G R+FL+
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  653  RFYEMVSSDRVKEDNNFEGLSLAHKLVQRVTDAIEKLSLNTIPSSFMEFINDFVK----L  708
            R Y ++++  + E+N+     + +  V+ VT+ ++++ +NT  + +M F+N   K    +
Sbjct  663  RVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLF  722

Query  709  AVYPKSAVEMAVRALAPIAPHISEELW-VLLGNSPGVQKSGWPSVLPEYLEGQTVTIVVQ  767
            + Y+K+ V++    +AP+APH++EELW  L +++ ++    WPS     L  + V IVVQ
Sbjct  723  SDYAKGFVQL----IAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQ  778

Query  768  VNGKLRARLDIMKDASKEEV--LALARESASKYLEGCEVKEAIFVPARLVNFVV  819
            ++GK++A+L + KD S+EE+  +ALA E     + G ++   I VP +LVN+V+
Sbjct  779  IKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

556) leuS in NC_012687


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  695 bits (2627),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 411/834 (50%), Positives = 599/834 (72%), Gaps = 22/834 (2%)

Query  3    YDPGLIEEKWQKFWENEQVFKAEEDETKTKYYVLDMFPYPSGAGLHVGHLIGYTATDIVA  62
            YD   IE KWQ FW +++ FK+  D +K K+Y LDMFPYPSGAGLHVGH  GYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRAQGFSVLHPMGWDSFGLPAEQYAIRTGTHPRETTEKNIANFKKQLTAMGFSYDESR  122
            R+KRAQG +VLHPMGWD+FGLPAEQYA+ TG +P E T  NIANFK+Q+ A+GFSYD  R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EFATSDPEYYKWTQKLFLILYEKGLAYMADMAVNYCPELGTVLSNEEI-ENGFSVDGGYP  181
            E  T+DP+YYKWTQ +F  LYEKGLAY A+++VN   ELGT ++NEE+  +G S  GGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRMLRQWVLRITAFADQLLEGLDELDWPESVKQLQKNWIGKSSGASVNFATEHGVIE-  240
            V R+ +RQW+L+ITA+A++LLE+L+E+DWPES+K++Q+NWIGKS+GA+V F   +   + 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  -VFTTRPDTLIGVSFLALAPEHPLVDLLTSDEQKAVVAQYIKETQSKSERDRISEMKTKS  299
             VFTTRPDTL+G ++  LAPEH+LVD +T+ +Q   VA+Y +++  KS+  R    K K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  300  GVFTGSYAKHPVTHELIPIWIADYVLMGFGSGAVMGVPAHDERDLLFAEQFNLPVVSVLN  359
            GV TGSYA +PV    +P+WIADYVL ++G+GA+M+VPAHDERD  FA QFNL +++VL+
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  360  KEGVCINSCCE-GFH-----LDGLSGEEAKQYVINFLEENHLGAAKIAYKLRDWLFSRQR  413
               V   +  E G+H     LDGL    A   +++ LE + +G  +++Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  414  YWGEPIPIIHFEDGSCRPLRDYELPLLPPEIQDYRPEGVGQGPLAKVREWVQVFDTETQR  473
            YWGEPIPIIH EDG+  ++ + ELPL+ P  +D RP G G++PLA+V +W++V   +  +
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  474  AGKRETHTMPQWAGSCWYYLRFCDAHNSAAPWAKEKEQYWMPVDLYIGGAEHAVLHLLYA  533
             G+RET+TMPQWAGS WYYLR+ D+HN+      E  + W+PVD+Y+GGAEHAVLHLLYA
Sbjct  484  -GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  534  RFWHQIFYEAGIVSTPEPFKKLVNQGLVLATSYRIPGKGYIYPE-IAKEENGKWVAPSGE  592
            RFWH+++Y+ G+V+T EPF+KL NQG++L+TSYR +  + +  + + K + +     +GE
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  593  ELDVRQEKMSKSKLNGVDPQILIDEFGADAVRMYAMFSGPLDKNKLWSNQGVAGCRRFLN  652
            EL+    KMSKS  N V+P+ +++++GAD++R+Y MF GPLD +  WS++G+ G R+FL+
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  653  RFYEMVSSDRVKEDNNFEGLSLAHKLVQRVTDAIEKLSLNTIPSSFMEFINDFVK----L  708
            R Y ++++  + E+N+     + +  V+ VT+ ++++ +NT  + +M F+N   K    +
Sbjct  663  RVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLF  722

Query  709  AVYPKSAVEMAVRALAPIAPHISEELW-VLLGNSPGVQKSGWPSVLPEYLEGQTVTIVVQ  767
            + Y+K+ V++    +AP+APH++EELW  L +++ ++    WPS     L  + V IVVQ
Sbjct  723  SDYAKGFVQL----IAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQ  778

Query  768  VNGKLRARLDIMKDASKEEV--LALARESASKYLEGCEVKEAIFVPARLVNFVV  819
            ++GK++A+L + KD S+EE+  +ALA E     + G ++   I VP +LVN+V+
Sbjct  779  IKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

557) A7249_00223 in NC_020944


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  695 bits (2627),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 411/834 (50%), Positives = 599/834 (72%), Gaps = 22/834 (2%)

Query  3    YDPGLIEEKWQKFWENEQVFKAEEDETKTKYYVLDMFPYPSGAGLHVGHLIGYTATDIVA  62
            YD   IE KWQ FW +++ FK+  D +K K+Y LDMFPYPSGAGLHVGH  GYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRAQGFSVLHPMGWDSFGLPAEQYAIRTGTHPRETTEKNIANFKKQLTAMGFSYDESR  122
            R+KRAQG +VLHPMGWD+FGLPAEQYA+ TG +P E T  NIANFK+Q+ A+GFSYD  R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EFATSDPEYYKWTQKLFLILYEKGLAYMADMAVNYCPELGTVLSNEEI-ENGFSVDGGYP  181
            E  T+DP+YYKWTQ +F  LYEKGLAY A+++VN   ELGT ++NEE+  +G S  GGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRMLRQWVLRITAFADQLLEGLDELDWPESVKQLQKNWIGKSSGASVNFATEHGVIE-  240
            V R+ +RQW+L+ITA+A++LLE+L+E+DWPES+K++Q+NWIGKS+GA+V F   +   + 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  -VFTTRPDTLIGVSFLALAPEHPLVDLLTSDEQKAVVAQYIKETQSKSERDRISEMKTKS  299
             VFTTRPDTL+G ++  LAPEH+LVD +T+ +Q   VA+Y +++  KS+  R    K K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  300  GVFTGSYAKHPVTHELIPIWIADYVLMGFGSGAVMGVPAHDERDLLFAEQFNLPVVSVLN  359
            GV TGSYA +PV    +P+WIADYVL ++G+GA+M+VPAHDERD  FA QFNL +++VL+
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  360  KEGVCINSCCE-GFH-----LDGLSGEEAKQYVINFLEENHLGAAKIAYKLRDWLFSRQR  413
               V   +  E G+H     LDGL    A   +++ LE + +G  +++Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  414  YWGEPIPIIHFEDGSCRPLRDYELPLLPPEIQDYRPEGVGQGPLAKVREWVQVFDTETQR  473
            YWGEPIPIIH EDG+  ++ + ELPL+ P  +D RP G G++PLA+V +W++V   +  +
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  474  AGKRETHTMPQWAGSCWYYLRFCDAHNSAAPWAKEKEQYWMPVDLYIGGAEHAVLHLLYA  533
             G+RET+TMPQWAGS WYYLR+ D+HN+      E  + W+PVD+Y+GGAEHAVLHLLYA
Sbjct  484  -GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  534  RFWHQIFYEAGIVSTPEPFKKLVNQGLVLATSYRIPGKGYIYPE-IAKEENGKWVAPSGE  592
            RFWH+++Y+ G+V+T EPF+KL NQG++L+TSYR +  + +  + + K + +     +GE
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  593  ELDVRQEKMSKSKLNGVDPQILIDEFGADAVRMYAMFSGPLDKNKLWSNQGVAGCRRFLN  652
            EL+    KMSKS  N V+P+ +++++GAD++R+Y MF GPLD +  WS++G+ G R+FL+
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  653  RFYEMVSSDRVKEDNNFEGLSLAHKLVQRVTDAIEKLSLNTIPSSFMEFINDFVK----L  708
            R Y ++++  + E+N+     + +  V+ VT+ ++++ +NT  + +M F+N   K    +
Sbjct  663  RVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLF  722

Query  709  AVYPKSAVEMAVRALAPIAPHISEELW-VLLGNSPGVQKSGWPSVLPEYLEGQTVTIVVQ  767
            + Y+K+ V++    +AP+APH++EELW  L +++ ++    WPS     L  + V IVVQ
Sbjct  723  SDYAKGFVQL----IAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQ  778

Query  768  VNGKLRARLDIMKDASKEEV--LALARESASKYLEGCEVKEAIFVPARLVNFVV  819
            ++GK++A+L + KD S+EE+  +ALA E     + G ++   I VP +LVN+V+
Sbjct  779  IKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

558) O179_01125 in NC_022110


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  695 bits (2628),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 411/834 (50%), Positives = 599/834 (72%), Gaps = 22/834 (2%)

Query  3    YDPGLIEEKWQKFWXNEQVFKAEEDETKTKYYVLDMFPYPSGAGLHVGHLIGYTATDIVA  62
            YD   IE KWQ FW +++ FK+  D +K K+Y LDMFPYPSGAGLHVGH  GYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRAQGFSVLHPMGWDSFGLPAEQYAIRTGTHPRETTEKNIANFKKQLTAMGFSYDESR  122
            R+KRAQG +VLHPMGWD+FGLPAEQYA+ TG +P E T  NIANFK+Q+ A+GFSYD  R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EFATSDPEYYKWTQKLFLILYEKGLAYMADMAVNYCPELGTVLSNEEI-ENGFSVDGGYP  181
            E  T+DP+YYKWTQ +F  LYEKGLAY A+++VN   ELGT ++NEE+  +G S  GGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRMLRQWVLRITAFADQLLEGLDELDWPESVKQLQKNWIGKSSGVSVNFATEHGAIE-  240
            V R+ +RQW+L+ITA+A++LLE+L+E+DWPES+K++Q+NWIGKS+G +V F   +   + 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  -VFTTRPDTLIGVSFLALAPEHPLVDLLTSDEQKAVVAQYIKETQSKSERDRISEMKTKS  299
             VFTTRPDTL+G ++  LAPEH+LVD +T+ +Q   VA+Y +++  KS+  R    K K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  300  GVFTGSYAKHPVTHELIPIWIADYVLMGFGSGAVMGVPAHDERDLLFAEQFNLPVVSVLN  359
            GV TGSYA +PV    +P+WIADYVL ++G+GA+M+VPAHDERD  FA QFNL +++VL+
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  360  KEGVCINSCCE-GFH-----LDGLSGEEAKQYVINFLEENHLGAAKIAYKLRDWLFSRQR  413
               V   +  E G+H     LDGL    A   +++ LE + +G  +++Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  414  YWGEPIPIIHFEDGSCRPLRDYELPLLPPEIQDYRPEGVGQGPLAKVREWVQVFDTETQR  473
            YWGEPIPIIH EDG+  ++ + ELPL+ P  +D RP G G++PLA+V +W++V   +  +
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  474  AGKRETHTMPQWAGSCWYYLRFCDAHNSAAPWAKEKEQYWMPVDLYIGGAEHAVLHLLYA  533
             G+RET+TMPQWAGS WYYLR+ D+HN+      E  + W+PVD+Y+GGAEHAVLHLLYA
Sbjct  484  -GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  534  RFWHQVFYEAGIVSTPEPFKKLVNQGLVLATSYRIPGKGYIYPE-IAKEENGKWVAPSGE  592
            RFWH+V+Y+ G+V+T EPF+KL NQG++L+TSYR +  + +  + + K + +     +GE
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  593  ELDVRQEKMSKSKLNGVDPQILIDEFGADAVRMYAMFSGPLDKNKLWSNQGVAGCRRFLN  652
            EL+    KMSKS  N V+P+ +++++GAD++R+Y MF GPLD +  WS++G+ G R+FL+
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  653  RFYEMVSSDRVKEDNNFEGLSLAHKLVQRVTDAIEKLSLNTIPSSFMEFINDFVK----L  708
            R Y ++++  + E+N+     + +  V+ VT+ ++++ +NT  + +M F+N   K    +
Sbjct  663  RVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLF  722

Query  709  AVYPKSALEMAVRALAPIAPHISEELW-VLLGNSPGVQKSGWPSVLPEYLEGQTVTIVVQ  767
            + Y+K+ +++    +AP+APH++EELW  L +++ ++    WPS     L  + V IVVQ
Sbjct  723  SDYAKGFVQL----IAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQ  778

Query  768  VNGKLRAQLDIMKDASKEEV--LALARESASKYLEGCEVKKAIFVPARLVNFVV  819
            ++GK++A+L + KD S+EE+  +ALA E     + G ++ K I VP +LVN+V+
Sbjct  779  IKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

559) BN418_1961 in NC_020557


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  694 bits (2625),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 422/649 (66%), Positives = 529/649 (82%), Gaps = 40/649 (6%)

Query  1    MRQWMLKITAYAdrllddldlvdWPENIKDMQRNWIGRSEGAEVTFKIKDSDETFNVFTT  60
            MRQWMLKITAYA+RLL+DL+ VDWPE+IKDMQRNWIG+S GA+VTFK+KD+D  F VFTT
Sbjct  189  MRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTT  248

Query  61   RPDTLFGATYTVFAPEHELIEKITTPEQKEAVESYKKQVELKSELERTDLAKDKTGVFTG  120
            RPDTLFGATY+V+APEH L++ ITT++Q EAV  YK+Q  LKS+L RTDLAK+KTGV TG
Sbjct  249  RPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTG  308

Query  121  AYAINPINGEEVPIWIADYVLIQYGTGAIMAVPAHDERDFEFAQQFGLNIRPVLEGGDVT  180
            +YAINP+NG E+P+WIADYVL  YGTGAIMAVPAHDERD EFA+QF L+I PVLEGG+V 
Sbjct  309  SYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVE  368

Query  181  KEAFTGDGPHINSDFLNGLAKAEAITAAIDWLEKEGIGSRKITYRLRDWLFSRQRYWGEP  240
              AFT DG HINSDFL+GL KA AI+  ++WLE EG+G+ ++TYRLRDWLFSRQRYWGEP
Sbjct  369  EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEP  428

Query  241  IPVIHWEDGettlvpeeelplllpkateIKPSGTGESPLANLHDWVNVTDENGRKGRRET  300
            IP+IHWEDG +T VPE ELPL+LP + +I+PSGTGESPLAN+ DW++VT E+G KGRRET
Sbjct  429  IPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVKGRRET  488

Query  301  NTMPQWAGSSWYFLRYIDPKNSEAIADKEKLAEWLPVDVYIGGAEHAVLHLLYARFWHKF  360
            NTMPQWAGSSWY+LRYIDP N+E +AD E L +WLPVD+Y+GGAEHAVLHLLYARFWHK 
Sbjct  489  NTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWHKV  548

Query  361  LYDIGVVPTKEPFQKLFNQGMILG---------------------------------ENN  387
            LYD+GVVPTKEPFQKLFNQGMILG                                 +  
Sbjct  549  LYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEELEQAP  608

Query  388  EKMSKSRGNVVNPDEVVEKYGADTLRLYEMFMGPLEASIAWNENGLEGARKFLDRIWRLL  447
             KMSKS  NVVNPD+VVE+YGADTLR+YEMFMGPL+ASIAW+E+GLEG+RKFLDR+ RL+
Sbjct  609  AKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLI  668

Query  448  VTEEGTLAEKVTTDANANLEKAYHHMVKTVTNHYENLRFNTGISQLMIFINEAYKQDTIP  507
             T E      +T + ++ L+K Y++ VK+VT++ ++++FNT+I+QLM+F+N A K+D + 
Sbjct  669  TTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLF  722

Query  508  KQYVEGFVQLLSPIAPHLAEELWEIL-GHTETISYVAWPTYDETKLVEDEVEIVLQVNGK  566
             +Y  GFVQL++P+APHL+EELW+ L +  E+ISYV+WP+YDE+KLVE++VEIV+Q++GK
Sbjct  723  SDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGK  782

Query  567  VKSKITVAKSLGKEELEKIAQEDNKMKENLEGKTIRKVIVVPGKLVNIV  615
            VK+K+ VAK L++EEL+ +A  ++K++ ++ GK I KVI VP KLVNIV
Sbjct  783  VKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIV  831

560) BN419_1962 in NC_020558


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  694 bits (2625),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 422/649 (66%), Positives = 529/649 (82%), Gaps = 40/649 (6%)

Query  1    MRQWMLKITAYAdrllddldlvdWPENIKDMQRNWIGRSEGAEVTFKIKDSDETFNVFTT  60
            MRQWMLKITAYA+RLL+DL+ VDWPE+IKDMQRNWIG+S GA+VTFK+KD+D  F VFTT
Sbjct  189  MRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTT  248

Query  61   RPDTLFGATYTVFAPEHELIEKITTPEQKEAVESYKKQVELKSELERTDLAKDKTGVFTG  120
            RPDTLFGATY+V+APEH L++ ITT++Q EAV  YK+Q  LKS+L RTDLAK+KTGV TG
Sbjct  249  RPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTG  308

Query  121  AYAINPINGEEVPIWIADYVLIQYGTGAIMAVPAHDERDFEFAQQFGLNIRPVLEGGDVT  180
            +YAINP+NG E+P+WIADYVL  YGTGAIMAVPAHDERD EFA+QF L+I PVLEGG+V 
Sbjct  309  SYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVE  368

Query  181  KEAFTGDGPHINSDFLNGLAKAEAITAAIDWLEKEGIGSRKITYRLRDWLFSRQRYWGEP  240
              AFT DG HINSDFL+GL KA AI+  ++WLE EG+G+ ++TYRLRDWLFSRQRYWGEP
Sbjct  369  EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEP  428

Query  241  IPVIHWEDGettlvpeeelplllpkateIKPSGTGESPLANLHDWVNVTDENGRKGRRET  300
            IP+IHWEDG +T VPE ELPL+LP + +I+PSGTGESPLAN+ DW++VT E+G KGRRET
Sbjct  429  IPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVKGRRET  488

Query  301  NTMPQWAGSSWYFLRYIDPKNSEAIADKEKLAEWLPVDVYIGGAEHAVLHLLYARFWHKF  360
            NTMPQWAGSSWY+LRYIDP N+E +AD E L +WLPVD+Y+GGAEHAVLHLLYARFWHK 
Sbjct  489  NTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWHKV  548

Query  361  LYDIGVVPTKEPFQKLFNQGMILG---------------------------------ENN  387
            LYD+GVVPTKEPFQKLFNQGMILG                                 +  
Sbjct  549  LYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEELEQAP  608

Query  388  EKMSKSRGNVVNPDEVVEKYGADTLRLYEMFMGPLEASIAWNENGLEGARKFLDRIWRLL  447
             KMSKS  NVVNPD+VVE+YGADTLR+YEMFMGPL+ASIAW+E+GLEG+RKFLDR+ RL+
Sbjct  609  AKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLI  668

Query  448  VTEEGTLAEKVTTDANANLEKAYHHMVKTVTNHYENLRFNTGISQLMIFINEAYKQDTIP  507
             T E      +T + ++ L+K Y++ VK+VT++ ++++FNT+I+QLM+F+N A K+D + 
Sbjct  669  TTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLF  722

Query  508  KQYVEGFVQLLSPIAPHLAEELWEIL-GHTETISYVAWPTYDETKLVEDEVEIVLQVNGK  566
             +Y  GFVQL++P+APHL+EELW+ L +  E+ISYV+WP+YDE+KLVE++VEIV+Q++GK
Sbjct  723  SDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGK  782

Query  567  VKSKITVAKSLGKEELEKIAQEDNKMKENLEGKTIRKVIVVPGKLVNIV  615
            VK+K+ VAK L++EEL+ +A  ++K++ ++ GK I KVI VP KLVNIV
Sbjct  783  VKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIV  831

561) leuS in NC_007716


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  693 bits (2619),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 413/852 (49%), Positives = 588/852 (70%), Gaps = 58/852 (6%)

Query  6    YDFKQIEHKWQLYWQQNNVFKTQDNFSKKKFYCLDMFPYPSSEGLHVGHIEGYTASDIMS  65
            YD   IE KWQ +W +N+ FKT  + SK KFY LDMFPYPS+ GLHVGH EGYTA+DI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  66   RFKRMQGFNVLHPFGWDSFGLPAEQYALQTGKNPRNFTYENINNFKKQIQSIGKSVDWDR  125
            RFKR QG NVLHP GWD+FGLPAEQYA++TG++P +FT ENI NFK+QI+++G S DWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  126  ELATSDPYFYAWTQWIFKKLYEKGLAVLKNIEVNFCPNLGTALANEEVISNEKGMFSERG  185
            E+ T+DP +Y WTQWIF KLYEKGLA   ++ VN   +LGTA+ANEEV+++     SERG
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGT---SERG  180

Query  186  NHPVVKKKMKQWVLKITQYADRLLDDLNLVNWPLNVKEMQANWIGKNQGAIVSFPVFDQK  245
              PVV+K M+QW+LKIT YA+RLL+DL+ V+WP ++K+MQ NWIGK+ GA V+F V D  
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  246  MTLKTFTNRPDTLFGVTFLVIAPEHELALQLTKTEHQQAVNNYLELTKQKKDLER-DINK  304
              +  FT RPDTLFG T+ V+APEH L   +T +++ +AV +Y   +  K DL R D+ K
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  305  DKTGVFTGSFAINPCNNTKIPIWIADYVLPHYGTGALMSVPCHDQRDFEFAQKHGLKMIQ  364
            +KTGV TGS+AINP N   +P+WIADYVL+ YGTGA+M+VP HD+RD EFA++  L +I 
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  365  VINPPSSDFAMPTTNQTQPPLTEAYTGEGIHINSDFLNGLNNEQAKTKMLQFLEKKNHGY  424
            V++  + +               A+T +G+HINSDFL+GL++  A +KM++ LE    G 
Sbjct  361  VLEGGNVE-------------EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGN  407

Query  425  PHYTYKLRDWVFSRQRYWAEPFPIYYDDSNNEIYTDSDTNLPIELPVLEQIKPSGTGESP  484
             + TY+LRDW+FSRQRYW+EP+PI   +      + ++++LP+ LPV  +I+PSGTGESP
Sbjct  408  ENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTST-AVPESELPLVLPVTKDIRPSGTGESP  466

Query  485  ISKAHFWLYFEK-DGKKYRRDCNTMPQLAGSSWYYIGYILKNHLGLIPLNTAKAKELLDY  543
            +++   WL   + DG K RR+ NTMPQ AGSSWYY+ YI  ++   ++       ELL  
Sbjct  467  LANVTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLA-----DEELLKQ  521

Query  544  YLPVDLYIGGTEHAVGHLLYARFWHKFLYDLGLVSTKEPFQKLVNQGIILG---------  594
             LPVD+Y+GG+EHAV HLLYARFWHK LYDLG+V+TKEPFQKL NQG+ILG         
Sbjct  522  WLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGA  581

Query  595  ------------------------HDHTKMSKSKGNGVSASLMLARYGADVLRIYIMFMG  630
                                    +  +KMSKS  N V++  ++ +YGAD LR+Y MFMG
Sbjct  582  LVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMG  641

Query  631  PLEDIKNWCEKGFKGIQRFLNRVYQMFSF-SMPNDFETSLNAIYHQTIFQTTQDYEKLKF  689
            PL+    W E G+ G ++FL+RVY++++   + ++   +L+ +Y++T+   T++ +++KF
Sbjct  642  PLDASIAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKF  701

Query  690  NKVISQLMIFVNQVYKHQKIGKKQAQIFLQLLNPIAPHLTEEINQTILKNKTQLVALTWP  749
            N  I+QLM+FVN   K++K+    A+ F+QL+ P+APHL EE+ Q++  +   +  + WP
Sbjct  702  NTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWP  761

Query  750  FYDKNHLEQLQVKIIVQVNSKLRAVLELPFNLSSEQIKIRALQDSKVNKFVCHKKIQNMI  809
             YD + L + +V I+VQ+++K++A L ++ +LS E+++  AL + KV+  +  K I ++I
Sbjct  762  SYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVI  821

Query  810  YIPNKLLNIIVN  821
             +PNKL+NI+++
Sbjct  822  AVPNKLVNIVIK  833

562) leuS in NC_010544


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  690 bits (2611),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 410/846 (49%), Positives = 580/846 (69%), Gaps = 55/846 (6%)

Query  6    YDFKKIEEHWQDYWKKHEIFKTKINKDQKKFYCLDMFPYPSSEGLHVGHIEGYAATDIVS  65
            YD   IE  WQ +W  ++ FKT  +  + KFY LDMFPYPS+ GLHVGH EGY+ATDI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  66   RFKRMQQYNVFHPFGWDSFGLPAEQYALKTGKNPRNFTYENIQKFKIQIQRLGKSVDWEK  125
            RFKR Q  NV+HP GWD+FGLPAEQYA+ TG++P +FT ENI +FK QI+ LG S DW++
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  126  ELATSDPYFYKWTQWIFKKLYEKNLAVLQNVEVYFCPALGTVLANEEVISNDKGLFSERG  185
            E+ T+DP +YKWTQWIF KLYEK LA   +V V     LGT +ANEEV++++    SERG
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGT---SERG  180

Query  186  NHPVIKKQMKQWVLKITDYAERLLADLDLVDWPQNVKDMQINWIGKSQGAVVSFPVFQQK  245
              PV++K M+QW+LKIT YAERLL DL+ VDWP+++KDMQ NWIGKS GA V+F V +  
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  246  NTLKVFTTRPYTLFGVTFLVIAPEHELLSQITTLKQQEEVLDYLECTKQKKTLER-NINK  304
            + + VFTTRP TLFG T+ V+APEH L+  ITT  Q E V DY   +  K  L R ++ K
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  305  DKSGVFTGSYAINPCNGEKIPIWVDDYVLPHFGTGILMGVPCHDQRDFEFAQKHHLKMIQ  364
            +K+GV TGSYAINP NG  +P+W+ DYVL+ +GTG +M+VP HD+RD EFA++ +L +I 
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  365  VVKPNPITDSSQKNPLEVFEGDGIIVNSDFLNGLDNNQAQTKMMQFLKEKKLAYPHYTYK  424
            V+    + +++       F  DG+ +NSDFL+GLD+  A +KM++ L    ++  + TY+
Sbjct  361  VLEGGNVEEAA-------FTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYR  413

Query  425  LHDWVFSRQRYWGEPLSIFYDENNNIHTMDDDSLPLELPVLDKIQPSGTGESPLSKASSW  484
            L+DW+FSRQRYWGEP++I+  E+    ++ +  LPL LPV   I+PSGTGESPL++ + W
Sbjct  414  LRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDW  473

Query  485  LYFEK-DGKKYRRDSNTMPQLAGSSWYYIAYVLKNISGITPLNTS--EAKELLDYYLPVD  541
            L   + DG K RR++NTMPQ AGSSWYY+ Y       I P NT      ELL   LPVD
Sbjct  474  LEVTREDGVKGRRETNTMPQWAGSSWYYLRY-------IDPHNTEKLADEELLKQWLPVD  526

Query  542  LYIGGTEHAVGHLLYARFWHKFLYDLGLVSQKEPFQKLVNQGMILG--------------  587
            +Y+GG+EHAV HLLYARFWHK LYDLG+V+ KEPFQKL NQGMILG              
Sbjct  527  IYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATD  586

Query  588  -------------------HDHTKMSKSKGNGVNASSMLEKYGADALRLHIMFMGPLEDV  628
                               +  +KMSKS  N VN+  ++E+YGAD+LR+  MFMGPL+  
Sbjct  587  KVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  629  KSWNEKGLQGIQRFLNRVHQMCSF-EMIDQKDVFLEKILHQTIQIVTQSYEKLKFNKAIS  687
             +W+E GL+G ++FL+RV ++ +  E+ +++   L+K+ ++T++ VT+  +++KFN AI+
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIA  706

Query  688  QLMIFVNHVYKSQKITKEQCQIFLQMLNPLTPHLTEELNATILKNKEMLVNMTWPHYNPK  747
            QLM+FVN   K +K+  +  + F+Q++ P++PHL EEL  ++  + E +  + WP Y+  
Sbjct  707  QLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDES  766

Query  748  YLGNEQSNIIVQVNGKTRSILTVSLGVSSEKIQKLAFQDQKVHKFIFQKQIQKVIYIPEK  807
             L +++ +I+VQ++GK ++ L V+ ++S E +Q +A+ ++KV+  I  K+I KVI +P+K
Sbjct  767  KLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNK  826

Query  808  LLNIIV  813
            L+NI++
Sbjct  827  LVNIVI  832

563) leuS in NC_021236


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  690 bits (2609),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 411/846 (49%), Positives = 581/846 (69%), Gaps = 55/846 (6%)

Query  6    YDFKKIEEHWQDYWKKHEIFKTKINKDQKKFYCLDMFPYPSSEGLHVGHIEGYAATDIVS  65
            YD   IE  WQ +W  ++ FKT  +  + KFY LDMFPYPS+ GLHVGH EGY+ATDI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  66   RFKRMQQYNVFHPFGWDSFGLPAEQYALKTGKNPRNFTYENIQKFKIQIQRLGKSVDWEK  125
            RFKR Q  NV+HP GWD+FGLPAEQYA+ TG++P +FT ENI +FK QI+ LG S DW++
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  126  ELATSDPYFYKWTQWIFKKLYEKKLAVLQNVEVYFCPALGTVLANEEVISNDKGLFSERG  185
            E+ T+DP +YKWTQWIF KLYEK LA   +V V     LGT +ANEEV++++    SERG
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGT---SERG  180

Query  186  NHPVIKKQMKQWVLKITDYAERLLADLDLVDWPQNVKDMQINWIGKSQGAVVSFPVFQQK  245
              PV++K M+QW+LKIT YAERLL DL+ VDWP+++KDMQ NWIGKS GA V+F V +  
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  246  NTLKVFTTRPYTLFGVTFLVIAPEHELLSQITTLKQQEEVLDYLECTKQKKTLER-NVNK  304
            + + VFTTRP TLFG T+ V+APEH L+  ITT  Q E V DY   +  K  L R ++ K
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  305  DKSGVFTGSYAINPCNGEKIPIWVADYVLPHFGTGILMGVPCHDQRDFEFAQKHHLKMIQ  364
            +K+GV TGSYAINP NG  +P+W+ADYVL+ +GTG +M+VP HD+RD EFA++ +L +I 
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  365  VVKPNPITDSSQKNPLEVFEGDGIIVNSDFLNGLDNNQAQTKMMQFLKEKKLAYPHYTYK  424
            V+    + +++       F  DG+ +NSDFL+GLD+  A +KM++ L    ++  + TY+
Sbjct  361  VLEGGNVEEAA-------FTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYR  413

Query  425  LHDWVFSRQRYWGEPLSIFYDENNNIHTMDDDSLPLELPVLDKIQPSGTGESPLSKASSW  484
            L+DW+FSRQRYWGEP++I+  E+    ++ +  LPL LPV   I+PSGTGESPL++ + W
Sbjct  414  LRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDW  473

Query  485  LYFEK-DGKKYRRDSNTMPQLAGSSWYYIAYVLKNISGITPLNTS--EAKELLDYYLPVD  541
            L   + DG K RR++NTMPQ AGSSWYY+ Y       I P NT      ELL   LPVD
Sbjct  474  LEVTREDGVKGRRETNTMPQWAGSSWYYLRY-------IDPHNTEKLADEELLKQWLPVD  526

Query  542  LYIGGTEHAVGHLLYARFWHKFLYDLGLVSQKEPFQKLVNQGMILG--------------  587
            +Y+GG+EHAV HLLYARFWHK LYDLG+V+ KEPFQKL NQGMILG              
Sbjct  527  IYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATD  586

Query  588  -------------------HDHTKMSKSKGNGVNASSMLEKYGADALRLHIMFMGPLEDV  628
                               +  +KMSKS  N VN+  ++E+YGAD+LR+  MFMGPL+  
Sbjct  587  KVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  629  KSWNEKGLQGIQRFLNRVHQMCSF-EMIDQKDVFLEKILHQTIQIVTQSYEKLKFNKAIS  687
             +W+E GL+G ++FL+RV ++ +  E+ +++   L+K+ ++T++ VT+  +++KFN AI+
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIA  706

Query  688  QLMIFVNHVYKSQKITKEQCQIFLQMLNPLTPHLTEELNATILKNKEILVNMTWPHYNPK  747
            QLM+FVN   K +K+  +  + F+Q++ P++PHL EEL  ++  + E +  + WP Y+  
Sbjct  707  QLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDES  766

Query  748  YLGNEQSNIIVQVNGKTRSILTVSLGVSSEKIQKLAFQDQKVHKFIFQKQIQKVIYIPEK  807
             L +++ +I+VQ++GK ++ L V+ ++S E +Q +A+ ++KV+  I  K+I KVI +P+K
Sbjct  767  KLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNK  826

Query  808  LLNIIV  813
            L+NI++
Sbjct  827  LVNIVI  832

564) Turpa_0238 in NC_018020


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  688 bits (2600),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 449/888 (51%), Positives = 603/888 (68%), Gaps = 97/888 (10%)

Query  3    YPFAEIEKKWQLYWENNQTFATGEDLSKPKYYVLDMFPYPSGAGLHVGHPEGYTATDIIA  62
            Y  + IE KWQ +W +N+TF TG D SKPK+Y LDMFPYPSGAGLHVGHPEGYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RKRRMQGFNVLHPMGWDAFGLPAERYAMQTGIHPKVTTKQNIDNFRRQLKSLGFSYDWSR  122
            R +R QG NVLHPMGWDAFGLPAE+YAM+TG +P   T +NI NF+RQ+++LGFSYDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EIDTTSPDYYKFTQWIFLKLFNSWYDAAAKKARPISELKIPSDLEGDAKKKEREDFIANH  182
            E++TT P+YYK TQWIF KL++                                      
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYE-------------------------------------K  146

Query  183  RLAYIANMPVNWCAELGTVLANEEV---DEWVGKGYKVERKPMRQWMLRITAYAERLLTD  239
             LAY A++PVNW  ELGT +ANEEV   +     GY V RKPMRQWML+ITAYAERLL D
Sbjct  147  GLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLED  206

Query  240  LEHVDWPAGTLELQKNWIGQSTGALVHFGIAGSPEKLTVFTTRPDTLYGVTFMVLAPEHP  299
            LE+VDWP +  ++Q+NWIG+STGA V F + ++   +TVFTTRPDTL+G T+ VLAPEH+
Sbjct  207  LEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHA  266

Query  300  LVDKIAADSAKAEIDAYRKTTALKTDLDRQLDAAKKEKTGVAIGAHAMHPVTGEKIPLYI  359
            LVD I++      +  Y++ ++LK+DL R      KEKTGV  G+ A++PV G  +P+ I
Sbjct  267  LVDAITTSDQAEAVADYKRQASLKSDLAR--TDLAKEKTGVWTGSYAINPVNGKEMPVWI  324

Query  360  ADYVLMGYGTGAIMAVPAHDERDFAFAQQFSLDIRQVVQPRESAAELPVTEDGVAINSPI  419
            ADYVL +YGTGAIMAVPAHDERD  FA+QF+LDI  V++   +  E + TEDG+ INS +
Sbjct  325  ADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEG-GNVEEAAFTEDGLHINSDF  383

Query  420  FDGLKTPEAKEKIIAHLEKEKLGERRIQYKLRDWLFSRQRYWGEPVPVSFDADGFMVaee  479
            +DGL  + A  K++  LE E +G+  + Y+LRDWLFSRQRYWGEP+P+    DG   A  
Sbjct  384  LDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVP  443

Query  480  esalplllpesKNFQPAGTGESPLANLPDWVNHEK-GGRKLRRETNTMPQWAGSSWYYLR  538
            ES LPL+LP +K+++P+GTGESPLAN+ DW++  + +G K RRETNTMPQWAGSSWYYLR
Sbjct  444  ESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLR  503

Query  539  FADTANKERFASAEKEKYWLNGGVDLYVGGAEHAVLHLLYARFWHKVLYDLGYVTSVEPF  598
            + D  N E++A  E  K WL   VD+YVGGAEHAVLHLLYARFWHKVLYDLG V + EPF
Sbjct  504  YIDPHNTEKLADEELLKQWLP--VDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPF  561

Query  599  KKLVHQGIILG---------------------------------EDGSKMSKSRGNVVNP  625
            +KL +QG+ILG                                 +  +KMSKS  NVVNP
Sbjct  562  QKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNP  621

Query  626  DTVVAEYGADTFRLYEMFMGPLEQMKPWQSKSIEGIYRFLGRVYRLYFGNTHSDENAPAQ  685
            D VV +YGADT+R+YEMFMGPL+   +W   ++EG  +FL+RVYRL   +  ++EN+   
Sbjct  622  DDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITEENSG--  679

Query  686  PTLSAKLLAAPADEKAVLKVLHQTIKKVSDDIETLSLNTAISQMMIFVNEAYRVESIGKE  745
                           A+ KV ++T+K V+++++ + +NTAI+Q+M+FVN A + + +  +
Sbjct  680  ---------------ALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFSD  724

Query  746  AAATFVKLLSPFAPHVAEEIWQALGEKG-SIALAPWPQFNAEYLVESSFEAVIQINGKIR  804
             A  FV+L++PFAPH++EE+WQAL   G SI+  PWP ++   LVE+  E V+QI+GK++
Sbjct  725  YAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVK  784

Query  805  GRTELAIGISDADFESAARSVDAVKAALEGKTVRKVIVVKNKMINFVV  852
            ++  +A ++S  +++  A + + V+A + GK + KVI V NK++N+V+
Sbjct  785  AKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

565) leuS in NC_005303


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  688 bits (2600),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 416/854 (49%), Positives = 587/854 (69%), Gaps = 62/854 (7%)

Query  6    YDFKQIEHKWQLYWQQNKVFKTQDNFSQKKFYCLDMFPYPSSEGLHVGHIEGYTASDIMS  65
            YD   IE KWQ +W +N  FKT  + S+ KFY LDMFPYPS+ GLHVGH EGYTA+DI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  66   RFKRMQGFNVLHPFGWDSFGLPAEQYALQTGKPPRTFTYENINNFKKQIQSIGKSVDWDR  125
            RFKR QG NVLHP GWD+FGLPAEQYA++TG+ P  FT ENI NFK+QI+++G S DWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  126  ELATSDPYFYSWTQWIFKKLYEKGLAVLKNTEVNFCPNLGTVLANEEVISNEKGMFSERG  185
            E+ T+DP +Y WTQWIF KLYEKGLA   +  VN   +LGT +ANEEV+++     SERG
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGT---SERG  180

Query  186  NHPVVKKKMKQWVLKITQYADRLLDDLNLVNWPLNVKEMQANWIGKNQGAIVSFPVSDQK  245
              PVV+K M+QW+LKIT YA+RLL+DL+ V+WP ++K+MQ NWIGK+ GA V+F V D  
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  246  ITLKTFTTRPDTLFGVTFLVIAPEHELALQLTKPEYQQAVNNYLELTKQKKDLER-DINK  304
              +  FTTRPDTLFG T+ V+APEH L   +T ++  +AV +Y   +  K DL R D+ K
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  305  DKTGVFTGSFAINPCNNTKIPIWIADYVLPHYGTGALMSVPCHDQRDFEFAQKHGLKMIQ  364
            +KTGV TGS+AINP N   +P+WIADYVL+ YGTGA+M+VP HD+RD EFA++  L +I 
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  365  VITPPSSDLENPTANQTNPPLTEAYTGEGIHINSDFLNGLNNEQAKTKILQFLEKNNHGY  424
            V       LE    +++      A+T +G+HINSDFL+GL++  A +K+++ LE +  G 
Sbjct  361  V-------LEGGNVEEA------AFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGN  407

Query  425  SHYTYKLRDWVFSRQRYWAEPFPIYYDDTNNKIYTDSDANLPIELPFLEQIKPSGTGESP  484
             + TY+LRDW+FSRQRYW+EP+PI   +      + ++++LP+ LP   +I+PSGTGESP
Sbjct  408  ENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTST-AVPESELPLVLPVTKDIRPSGTGESP  466

Query  485  LSKAHFWLYFEK-DGKKYRRDSNTMPQLAGSSWYYIGYILKNYLGIIPLNTTK--AKELL  541
            L++   WL   + DG K RR++NTMPQ AGSSWYY+ Y       I P NT K    ELL
Sbjct  467  LANVTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRY-------IDPHNTEKLADEELL  519

Query  542  DYYLPVDLYIGGTEHAVGHLLYARFWHKFLYDLGLVSTKEPFQKLVNQGIILG-------  594
               LPVD+Y+GG+EHAV HLLYARFWHK LYDLG+V+TKEPFQKL NQG+ILG       
Sbjct  520  KQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSR  579

Query  595  --------------------------HDHTKMSKSKGNGVSSSLMLARYGADVLRIYIMF  628
                                      +  +KMSKS  N V++  ++ +YGAD LR+Y MF
Sbjct  580  GALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMF  639

Query  629  MGPLEDIKSWCEKGFKGIQRFLNRVYQMFSF-AMPNDFETSLNAIYHQTIFQTTQDYEKL  687
            MGPL+   +W E G+ G ++FL+RVY++++   + ++   +L+ +Y++T+   T++ +++
Sbjct  640  MGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQM  699

Query  688  KFNKVISQLMIFVNQVYKHQKIGKKQAQTFLQLLNPIVPHLTEEINQTILKNNNQLVALT  747
            KFN  I+QLM+FVN   K++K+    A+ F+QL+ P+ PHL EE+ Q++  + + +  + 
Sbjct  700  KFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVP  759

Query  748  WPLHDKTHLEQLQVKIIVQVNSKLRAVLELPCDLSSEQIKTLALQDAKVNKFVCHKNIQN  807
            WP  D + L + +V I+VQ+++K++A L ++ DLS E+++ +AL + KV+  +  K+I +
Sbjct  760  WPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIK  819

Query  808  MIYIPNKLLNIIVN  821
            +I +PNKL+NI+++
Sbjct  820  VIAVPNKLVNIVIK  833

566) leuS in NC_006055


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  687 bits (2597),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 433/808 (54%), Positives = 578/808 (72%), Gaps = 50/808 (6%)

Query  34   VLDMFPYPSGAGIHVGHVKGYTATDVFSRYKRMNGYDVLHPMGWDAFGLPAEQYALKTGN  93
             LDMFPYPSGAG+HVGH  GYTATD++SR+KR +G +VLHPMGWDAFGLPAEQYA+ TGN
Sbjct  36   ALDMFPYPSGAGLHVGHPEGYTATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGN  95

Query  94   DPIDFTLENIKTFKRQLKMMGFSYDFDKEISTANPNYYKITQWIFNQLYKKGLAENRDVE  153
            DP +FT ENI  FKRQ++ +GFSYD D+E++T++PNYYK TQWIF +LY KGLA + +V 
Sbjct  96   DPAEFTAENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVP  155

Query  154  VNWCQELGTVLANDEIIEKDGLMVSERGEHPVTKRKMRQWVLKITEYADRLLEGLDELEW  213
            VNW +ELGT +AN+E++  +    SERG  PV ++ MRQW+LKIT YA+RLLE+L+E++W
Sbjct  156  VNWVEELGTAIANEEVLPDG---TSERGGYPVVRKPMRQWMLKITAYAERLLEDLEEVDW  212

Query  214  NSSIKDLQRNWIGKSTGVELDFLVNNI--KVPVFTTRIDTIYGVSYIVLAPEHEQVLNIT  271
              SIKD+QRNWIGKSTG ++ F V++      VFTTR DT++G +Y VLAPEH  V  IT
Sbjct  213  PESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHALVDAIT  272

Query  272  TPEQLKEVQTYIELAKNKSEIDRKDESKPKTGVFTGSYATNPHTNELVQVWVSDYVLANY  331
            T++Q   V  Y   A  KS++ R D +K KTGV TGSYA NP     + VW++DYVLA+Y
Sbjct  273  TSDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASY  332

Query  332  GTGAVMAVPAHDKRDWEFATKFNLEKKFVIE-NKTDEKAFVGEGKIINSDILNGMDKKQA  390
            GTGA+MAVPAHD RDWEFA +FNL+   V+E  + +E AF  +G  INSD+L+G+DK  A
Sbjct  333  GTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEAAFTEDGLHINSDFLDGLDKASA  392

Query  391  IQTMTKIAIEQGWGREQTNYKLRDWLFSRQRFYGEPFPVLY--GPNQEITLIEDLPVELP  448
            I  M      +G G E+  Y+LRDWLFSRQR+ GEP+P++   +         +LP+ LP
Sbjct  393  IAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLP  452

Query  449  RIKNIKPSGTGESPLANVEEWVNVEI-DGVKYRRETNTMPQSAGSSWYYLAYILADGENE  507
              K+I+PSGTGESPLANV +W++V   DGVK RRETNTMPQ AGSSWYYL YI ++  + 
Sbjct  453  VTKDIRPSGTGESPLANVTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEK  512

Query  508  FIDIDSAEAKKRFEKWMPVDLYVGGQEHAVGHLLYARFWNYVLYDLGITSVKEPFKQLFN  567
            + D +       + +W+PVD+YVGG EHAV HLLYARFW+ VLYDLG+ + KEPF++LFN
Sbjct  513  LADEEL------LKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFN  566

Query  568  QGMILGP---DGR------------------------------KMSKSWGNVINPDDIVS  594
            QGMILG    D+R                              KMSKS  NV+NPDD+V 
Sbjct  567  QGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVE  626

Query  595  THGADSLRLYEMFMGPLDASLPWSEDGLDSALKWIHRAYRMVMTTELTDVNDTKLDFVYN  654
              GAD+LR+YEMFMGPLDAS++WSE+GL+++ K ++R YR++ T E+T+ N   LD VYN
Sbjct  627  QYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALDKVYN  686

Query  655  DVVKNVSEMIESLKFNTAISQLMIFVNAVYKHEGPVYRPYIEGFVKMLSIYAPFIGEELW  714
            + VK V+E ++ +KFNTAI+QLM+FVNA  K E+ ++  Y  GFV++++ +AP +GEELW
Sbjct  687  ETVKAVTEQVDQMKFNTAIAQLMVFVNAANK-EDKLFSDYAKGFVQLIAPFAPHLGEELW  745

Query  715  EKL-GHAPSITKQAWPVFDPSKLVSNTVVIALQINGKLRATIEVEKGTIKDKLLELAKKQ  773
            + L + + SI+  +WP +D SKLV N V I +QI+GK++A + V K+  ++ L E+A  +
Sbjct  746  QALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALAN  805

Query  774  ESIISYIKDKEIIKEIAVVDRIVNIVIK  801
            E + + I +K+IIK IAV +++VNIVIK
Sbjct  806  EKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

567) leuS in NC_012778


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  687 bits (2598),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 434/839 (52%), Positives = 589/839 (71%), Gaps = 47/839 (5%)

Query  16   YNHKTVEKKWQQIWQDEKAFAATNDYSKPKYYALVEFPYPSGQGLHVGHPRPYTALDIVA  75
            Y+H ++E KWQ +W D+ +F +  D SKPK+YAL  FPYPSG GLHVGHP  YTA DI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  76   RKRRMQGYNVLYPMGWDAFGLPTENYAIKNKIHPKIVTKNNIDHFKEQLQSIGYSFDWDR  135
            R +R QG NVL PMGWDAFGLP+E+YA+    +P   T +NI +FK Q++++G+S+DWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  136  EINTTDPDYYKWTQWIFLKLFKAGLAYKQEMPINWCTSCKVGLANEEVV-NGVCERCGSP  194
            E+NTTDP+YYKWTQWIF KL+  GLAY  E+P+NW      ++ANEEV+ +G  ER G P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  195  VVRKVKSEWMLKITDYADKLIEGLDHVDYIERVKTQQKNWIGRSTGAEVDFAIAGKEDKL  254
            VVRK   +WMLKIT YA++L+E+L++VD  E +K  Q+NWIG+STGA+V F + + +  +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  255  RIYTTRCDTLFGVTYMVVSPEHPYLDKYKDEIKNWDEIESYREQASRKSDFERAELAKDK  314
             ++TTR DTLFG TY V++PEH+ +D      +  + +  Y+ QAS KSD+ R++LAK+K
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQA-EAVADYKRQASLKSDLARTDLAKEK  302

Query  315  TGVEIDGLKAVNPVNGKEVPIWVSDYVLMSYGTGAIMAVPAHDERDWEFAKKFNLPIIQV  374
            TGV  ++  A+NPVNGKE+P+W++DYVL SYGTGAIMAVPAHDERDWEFAK+FNL II V
Sbjct  303  TGVWTGSY-AINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  375  VAKNGEEVDVNEAAFTDVATGVLINSDFINGLEVKEAKEKMIEFLTEKGIGNAKVNYKLR  434
            +    E  +V+EAAFT+   G+ INSDF++GL+   A  KM+E L   G+GN +V Y+LR
Sbjct  362  L----EGGNVEEAAFTE--DGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  435  DWVFSRQRYWGEPIPIVHCDKCGYvpvdeselplllpevesYMPTDNGESPLAAMTDWVN  494
            DW+FSRQRYWGEPIPI+H +     +V ESELPL+LP      P++ GESPLA +TDW++
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  495  TTCPCCGGPAKRETDTMPQWAGSSWYFLRYTDPHNTETLASQEALKYWLPVDWYNGGMEH  554
             T    G  ++RET+TMPQWAGSSWY+LRY DPHNTE LA +E LK WLPVD Y GG EH
Sbjct  476  VTRE-DGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEH  534

Query  555  TTLHLLYSRFWHRFLYDQKVVPCPEPYQKRTSHGMILG----------------------  592
            + LHLLY+RFWH+ LYD  VVP  EP+QK  ++GMILG                      
Sbjct  535  AVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGS  594

Query  593  -----------ENGEKMSKSRGNVVNPDDIVRDYGADTLRTYEMFIGAFDAAASWSEDGV  641
                       +   KMSKS  NVVNPDD+V +YGADTLR YEMF+G++DA+ +WSE+G+
Sbjct  595  FFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGL  654

Query  642  KGCRRFLDRVWKLQDIMTDEEGFSKEFETKMHQTIKKVSFDYENLKYNTAIAQLMTMLND  701
             G R+FLDRV +L       E  S  ++   ++T+K V+ + +++K+NTAIAQLM  +N 
Sbjct  655  EGSRKFLDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNA  714

Query  702  FSKAGKITKGELKTYLILLNPVAPHITEEMWEAIGENGRVYQ-QTWPEYDEAKTVESMVE  760
             +K +K+  +  K ++ L+ P APH+ EE+W+A+  +G       WP YDE+K VE+ VE
Sbjct  715  ANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVE  774

Query  761  IAVQINGKTKATINIAKDADKDSV--IAAAKEALGSRLSG-NIIKEIYVPGRIVNIVAK  816
            I VQI+GK KA + +AKD  ++ +  +A A+E + + ++G +IIK I VP ++VNIV K
Sbjct  775  IVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

568) Cphy_0938 in NC_010001


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  687 bits (2598),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 406/826 (50%), Positives = 591/826 (72%), Gaps = 55/826 (6%)

Query  23   TFKTDVWDFSKPKYYVLDMFPYPSGVGLHAGHPEGYTATDIVSRMKRMQGYNVLHPMGYD  82
            TFKT+  D SKPK+Y LDMFPYPSG GLH GHPEGYTATDI+SR KR QG NVLHPMG D
Sbjct  22   TFKTGT-DASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSRFKRAQGHNVLHPMGWD  80

Query  83   SFGLPAEQYAVSTGNHPNGFTEKNIESFSKQLKELGFDYDWSKMIATSDPKFYKWTQWIF  142
            +FGLPAEQYA+ TGN+P  FT  NI +F +Q++ LGF YDW + + T+DP++YKWTQWIF
Sbjct  81   AFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIF  140

Query  143  KQLYLDGYAKYIDMPVNWCEELGTVLSNDEVI-DGKSERGGYPVIRKNMKQWVINQPAFA  201
             +LY  G A   ++PVNW EELGT ++N+EV+ DG SERGGYPV+RK M+QW+++  A+A
Sbjct  141  TKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYA  200

Query  202  EKLLEGLEEIDWPESTKDMQRHWIGKSEGVEVDLEIVGGG-NFSIYTTCIETIYGITFMV  260
            E+LLE+LEE+DWPES KDMQR+WIGKS G +V + + + + +F+++TT  +T++G T+ V
Sbjct  201  ERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAV  260

Query  261  LAPDGQIVKDLMPRIENKEEVEAYINETLKKNDMDRTELNKTKSGCILKGIYAINPVNGK  320
            LAP+  +V  +    ++ E V  Y  ++  K+D+ RT+L K K+G +  G YAINPVNGK
Sbjct  261  LAPEHALVDAITTS-DQAEAVADYKRQASLKSDLARTDLAKEKTG-VWTGSYAINPVNGK  318

Query  321  EVPLFIGDFVLASYGTGAVMAVPSHDQRDFEYAMVHNIPMIQVIDGADVSEKAFEKGDYL  380
            E+P+ I+D+VLASYGTGA+MAVP+HD+RD E+A   N+ +I V++G++V E AF  ++ L
Sbjct  319  EMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEAAFTEDG-L  377

Query  381  GKGCKLMNSEEFTGLTVEEAKGAITEKLSKMGVARKSVNYHFREWIFARQRYWGEPVPVV  440
                 +++     GL    A + + E L   GV+  +V Y++R+W+F+RQRYWGEP+P++
Sbjct  378  HINSDFLD-----GLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPII  432

Query  441  YTENDEIHVLSDNELPLILPVLEDYKGK-NGKAPLENATEWKQYEK-DGVKGKRETSTMP  498
              E++    ++++ELPL+LPV  D +    G +PL N T+W +  + DGVKG+RET+TMP
Sbjct  433  HWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVKGRRETNTMP  492

Query  499  GSAGSSWYFMRYIDPDNQEEFANQELLKHWLPVDLYIGGPEHAVGHLMYSRIWNRYLYDK  558
              AGSSWY++RYIDP+N E +A++ELLK+WLPVD+Y+GG+EHAV HL+Y+R+W++ LYD 
Sbjct  493  QWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDL  552

Query  559  GLSPVKEPFKKLVHQGMILGSN----------GIKMGKRFPEF-----------------  591
            G+ P KEPF+KL +QGMILG++            K+ KR   F                 
Sbjct  553  GVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEELEQAPAKMS  612

Query  592  -----VVNPSDIIRDYGADTLRLYEMFMGPLEVSKPWNQQGVEGARKFINRVWTFFTNEE  646
                 VVNP D++ +YGADTLR+YEMFMGPL+ S +W+++G+EG+RKF++RV  ++T  E
Sbjct  613  KSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKE  672

Query  647  NITDDNKDSLTKVYHQTVKKVTSDFEQLGFNTAISQMMIFVNSVYKVGSCPREYAEGFIK  706
             IT++N ++L KVY++TVK VT + +Q+ FNTAI+Q+M+FVN+  K +    +YA GF++
Sbjct  673  -ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQ  731

Query  707  MYSCICPHVGEEMWNVL-GHNNTLANESWPTYDEDAIKEDTITIGVQVNGKVKGTV----  761
            + + + PH+GEE+W+ L +  ++++  +WP+YDE  + E+ + I VQ++GKVK+ +    
Sbjct  732  LIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAK  791

Query  762  ELSVDEENDSALAKAKEVPTVAKAIEGNAIVKEIYVKGKIINIVVK  807
            +LS +E ++ ALA+ K    V   I G+ I+K I V  K++NIV+K
Sbjct  792  DLSREELQEVALANEK----VQAEIAGKDIIKVIAVPNKLVNIVIK  833

569) FP2_02300 in NC_021042


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  686 bits (2594),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 437/849 (52%), Positives = 591/849 (70%), Gaps = 22/849 (2%)

Query  3    YDYKAVEAKWQKVWEDEKTFHAEIDHKKPKFYALVEFPYPSGAGLHVGHPRSYTALDVVS  62
            YD  A+E+KWQ  W D+ TF +  D  KPKFYAL  FPYPSGAGLHVGHP +YTA D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RKRRQNGYNVLYPMGWDAFGLPTENFAMKNHIHPAIVTKKNVDHFREQLKALGFSFDWDR  122
            R +R +G NVL PMGWDAFGLP+E++AM    +PA  T  N+ +F+ Q++ALGFS+DWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EINTTDPEYYKWTQWIFLQLYKKGLAYKKEMNVNWCTGCKCVLANEEVV-NGVCERCGSE  181
            E+NTTDP+YYKWTQWIF +LY KGLAY  E+ VNW       +ANEEV+ +G  ER G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VVHRVKSQWMLKITAYADKLIDGLDGLDYIERVATQQKNWIGRSHGAEVNFGTTAGDT-L  240
            VV++   QWMLKITAYA++L+++L+ +D  E +   Q+NWIG+S GA+V F     D  +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  TVYTTRCDTLFGATYMVVSPEHAILKEWLEKGIIKNADAVKAYQAEAARKSDFERSELNK  300
            TV+TTR DTLFGATY V++PEHA++          +A+AV  Y+ +A+ KSD+ R++L K
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVD---AITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  301  EKTGVQLEGVMGINPVNDKEIPIFISDYVLATYGTGAIMAVPAHDTRDWEFAKKFGLPII  360
            EKTGV   G  +INPVN+KE+P+ I+DYVLA+YGTGAIMAVPAHD RDWEFAK+F L II
Sbjct  301  EKTGV-WTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDII  359

Query  361  EVVKGSTPSNLDEAAFTDVATGTLVNSGFLDGLSVTDAKKKMIEWLEANGKGRDKVNYKL  420
             V+ G   +N++EAAFT+   G  +NS+FLDGL  + A  KM+EWLEA+G G ++V Y+L
Sbjct  360  PVLEG---GNVEEAAFTE--DGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRL  414

Query  421  RDWVFSRQRYWGEPIPMVKCEKCGWQplpesslpltlpDITDFEPGPDGESPLARHTDWV  480
            RDW+FSRQRYWGEPIP++  E     ++PES LPL LP   D+ P+  GESPLA  TDW+
Sbjct  415  RDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWL  474

Query  481  RTTCPCCGGPATRETDTMPQWAGSSWYFLRYMDPHCKDALASKEALEYWSPVDWYNGGME  540
              T    G  + RET+TMPQWAGSSWY+LRY+DPH  + LA  E L  W PVD Y GG E
Sbjct  475  EVTRE-DGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAE  533

Query  541  HTTLHLLYSRFWHKFLYDIGVVPSPEPYQKRTAHGMILGLNPHSFVNLPAEEQEKLLKEY  600
            H+ LHLLY+RFWHK LYD+GVVP+ EP+QK   +GMILG + +       + +  L+   
Sbjct  534  HAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYR-------DSRGALVATD  586

Query  601  GSQKAAEKALEEKYGEMARHPIVKMSKSLGNVINPDEVVDQYGADTMRLYEMFMGDFEQA  660
              +K     ++   GE   ++  KMSKSL NV+NPD+VV+QYGADT+R+YEMFMG ++ +
Sbjct  587  KVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  661  APWQTSAIAGCNRFLDRVWALSDKLVEGEGYRPQLETLLHQTIKKVGADIEGLKMNTAIA  720
             +W   ++ G  +FLDRV  L       E     L+ + ++T+K V  +++ +K NTAIA
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIA  706

Query  721  QLMTLVNALYDNGGATRAEFETV-VQLLNPFAPHMTEELWEKLGHSHDEQLAYYPWPKYE  779
            QLM +VNA  ++ +   +++    VQL+ PFAPH+ EELW+ L  + +E ++Y PWP Y+
Sbjct  707  QLMVFVNAA-NKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALT-ASGESISYVPWPSYD  764

Query  780  EAKCVESTVEIAVQVNGKVKARLKVAADITSEDaiaaakadpavaeaLSGKTVVKEIYVK  839
            E+K VE+ VEI VQ++GKVKA+L VA D++ E+    A A+  V   ++GK ++K I V 
Sbjct  765  ESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVP  824

Query  840  GRLVNLAVK  848
             +LVN+ +K
Sbjct  825  NKLVNIVIK  833

570) leuS in NC_019391


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  685 bits (2589),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 406/836 (49%), Positives = 596/836 (72%), Gaps = 25/836 (2%)

Query  3    YDPSLIEKKWQQFWKEHKSFKADETADKPKYYVLDMFPYPSGAGLHVGHLIGYTATDIVA  62
            YD + IE KWQ FW ++ +FK++  A KPK+Y LDMFPYPSGAGLHVGH  GYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRAKGFSVLHPMGWDSFGLPAEQYAVRTGTHPRETTKKNIENFRKQLSAMGFSYDEGR  122
            R+KRA+G +VLHPMGWD+FGLPAEQYA+ TG +P E T  NI NF++Q++A+GFSYD +R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EFATSDPDYYRWTQKLFLFLYEKGLAYMADMAVNYCEELGTVLANEEV-ENGLSVEGGYP  181
            E  T+DP+YY+WTQ +F  LYEKGLAY A+++VN  EELGT +ANEEV  +G S  GGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRMLRQWILRITAYSDHLLQGLEDLDWPENVKQLQRNWIGKSEGALVRFEV-DNGNFL  240
            V R+ +RQW+L+ITAY+++LL++LE++DWPE++K++QRNWIGKS GA V F V D ++ +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  SVFTTRPDTLCGVSFLVMAPEHPEINHLVSEEQRSAVENYIRCVQSKSERERISETKVKS  300
            +VFTTRPDTL G ++ V+APEH+ ++ + + +Q  AV +Y R    KS+  R   +K K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  301  GVFIGAYAKHPITGAPLPIWVSDYVIMGYGSGVVMGVPAHDERDREFANAFALPISEVLD  360
            GV  G+YA +P+ G  +P+W++DYV+ +YG+G +M+VPAHDERD+EFA+ F L I  VL+
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  361  DNG--------QCIHSNHEDFLLNGLRGKEASDYVIAYLQKKNLGEAKVVYKLRDWLFSR  412
            +          + +H N +  +L+GL    A   ++  L+   +G+ +V Y+LRDWLFSR
Sbjct  364  GGNVEEAAFTEDGLHINSD--FLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSR  421

Query  413  QRYWGEPIPIIHFEDGTCRpleddelpllppeIQDYRPKGFGQGPLANVKEWVEIHDVKT  472
            QRYWGEPIPIIH EDGT  ++ + ELPL+ P  +D RP G G++PLANV +W+E+     
Sbjct  422  QRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTR-ED  480

Query  473  NRKGRRETHTMPQWAGSCWYYLRFCDAHNSQAPWSNENERYWMPVDLYIGGAEHAVLHLL  532
              KGRRET+TMPQWAGS WYYLR+ D+HN++    +E  + W+PVD+Y+GGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  533  YSRFWHRVFYEAGLVSTPEPFKKLINQGLVLATSYRIPGKGYVHPEDVREDNGK-WTTAS  591
            Y+RFWH+V+Y+ G+V+T EPF+KL+NQG++L+TSYR +  + V  + V   +G      +
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  592  GEELEVRQEKMSKSKLNGVDPQTLIDEFGADALRMYAMFSGPLDKNKLWCNHGVSGCRRF  651
            GEELE    KMSKS  N V+P+ +++++GAD+LR+Y MF GPLD +  W ++G+ G R+F
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  652  LNRFYELVTSSAVQDVDDPKGMALAHKLVHRVGEDIEKMSLNTIPSSFMEFINEFTK---  708
            L+R Y L+T+  + + +      + +  V  V E++++M +NT  + +M F+N   K   
Sbjct  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  709  -LDTYPKSALAMVVRALAPIAPHISEELWTIL-GYAPGIDKAGWPEVDPKYLEDASVTFV  766
             +  Y+K+ + ++    AP+APH++EELW  L + + +I    WP  D   L +  V +V
Sbjct  721  LFSDYAKGFVQLI----APFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  767  IQVNGKLRARLDIDKNTSQEDI--LSAARESVAKYLEDKEIKKEVFVPNRLVNFVL  820
            +Q++GK++A+L + K+ S+E++  ++ A E V   + +K+I K + VPN+LVN+V+
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

571) leuS in NC_018627


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  685 bits (2589),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 406/836 (49%), Positives = 596/836 (72%), Gaps = 25/836 (2%)

Query  3    YDPSLIEKKWQQFWKEHKSFKADETADKPKYYVLDMFPYPSGAGLHVGHLIGYTATDIVA  62
            YD + IE KWQ FW ++ +FK++  A KPK+Y LDMFPYPSGAGLHVGH  GYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRAKGFSVLHPMGWDSFGLPAEQYAVRTGTHPRETTKKNIENFRKQLSAMGFSYDEGR  122
            R+KRA+G +VLHPMGWD+FGLPAEQYA+ TG +P E T  NI NF++Q++A+GFSYD +R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EFATSDPDYYRWTQKLFLFLYEKGLAYMADMAVNYCEELGTVLANEEV-ENGLSVEGGYP  181
            E  T+DP+YY+WTQ +F  LYEKGLAY A+++VN  EELGT +ANEEV  +G S  GGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRMLRQWILRITAYSDHLLQGLEDLDWPENVKQLQRNWIGKSEGALVRFEV-DNGNFL  240
            V R+ +RQW+L+ITAY+++LL++LE++DWPE++K++QRNWIGKS GA V F V D ++ +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  SVFTTRPDTLCGVSFLVMAPEHPEINHLVSEEQRSAVENYIRCVQSKSERERISETKVKS  300
            +VFTTRPDTL G ++ V+APEH+ ++ + + +Q  AV +Y R    KS+  R   +K K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  301  GVFIGAYAKHPITGAPLPIWVSDYVIMGYGSGVVMGVPAHDERDREFANAFALPISEVLD  360
            GV  G+YA +P+ G  +P+W++DYV+ +YG+G +M+VPAHDERD+EFA+ F L I  VL+
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  361  DNG--------QCIHSNHEDFLLNGLRGKEASDYVIAYLQKKNLGEAKVVYKLRDWLFSR  412
            +          + +H N +  +L+GL    A   ++  L+   +G+ +V Y+LRDWLFSR
Sbjct  364  GGNVEEAAFTEDGLHINSD--FLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSR  421

Query  413  QRYWGEPIPIIHFEDGTCRpleddelpllppeIQDYRPKGFGQGPLANVKEWVEIHDVKT  472
            QRYWGEPIPIIH EDGT  ++ + ELPL+ P  +D RP G G++PLANV +W+E+     
Sbjct  422  QRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTR-ED  480

Query  473  NRKGRRETHTMPQWAGSCWYYLRFCDAHNSQAPWSNENERYWMPVDLYIGGAEHAVLHLL  532
              KGRRET+TMPQWAGS WYYLR+ D+HN++    +E  + W+PVD+Y+GGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  533  YSRFWHRVFYEAGLVSTPEPFKKLINQGLVLATSYRIPGKGYVHPEDVREDNGK-WTTAS  591
            Y+RFWH+V+Y+ G+V+T EPF+KL+NQG++L+TSYR +  + V  + V   +G      +
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  592  GEELEVRQEKMSKSKLNGVDPQTLIDEFGADALRMYAMFSGPLDKNKLWCNHGVSGCRRF  651
            GEELE    KMSKS  N V+P+ +++++GAD+LR+Y MF GPLD +  W ++G+ G R+F
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  652  LNRFYELVTSSAVQDVDDPKGMALAHKLVHRVGEDIEKMSLNTIPSSFMEFINEFTK---  708
            L+R Y L+T+  + + +      + +  V  V E++++M +NT  + +M F+N   K   
Sbjct  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  709  -LDTYPKSALAMVVRALAPIAPHISEELWTIL-GYAPGIDKAGWPEVDPKYLEDASVTFV  766
             +  Y+K+ + ++    AP+APH++EELW  L + + +I    WP  D   L +  V +V
Sbjct  721  LFSDYAKGFVQLI----APFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  767  IQVNGKLRARLDIDKNTSQEDI--LSAARESVAKYLEDKEIKKEVFVPNRLVNFVL  820
            +Q++GK++A+L + K+ S+E++  ++ A E V   + +K+I K + VPN+LVN+V+
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

572) leuS in NC_018619


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  684 bits (2586),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 406/835 (49%), Positives = 597/835 (72%), Gaps = 23/835 (2%)

Query  3    YDPSLVEKKWQQFWKEHKSFKADETADKPKYYVLDMFPYPSGAGLHVGHLIGYTATDIVA  62
            YD + +E KWQ FW ++ +FK++  A KPK+Y LDMFPYPSGAGLHVGH  GYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRAKGFSVLHPMGWDSFGLPAEQYAVRTGTHPRETTKKNIENFRKQLSAMGFSYDEGR  122
            R+KRA+G +VLHPMGWD+FGLPAEQYA+ TG +P E T  NI NF++Q++A+GFSYD +R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EFATSDPDYYRWTQKLFLFLYEKGLAYMADMAVNYCEELGTVLANEEV-ENGLSVEGGYP  181
            E  T+DP+YY+WTQ +F  LYEKGLAY A+++VN  EELGT +ANEEV  +G S  GGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRMLRQWILRITAYSDQLLQGLEDLDWPENVKQLQRNWIGKSEGALVRFEV-DNGNFL  240
            V R+ +RQW+L+ITAY+++LL++LE++DWPE++K++QRNWIGKS GA V F V D ++ +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  SVFTTRPDTLCGVSFLVMAPEHPEINHLVSEEQRSAVENYIRCVQSKSERERISETKVKS  300
            +VFTTRPDTL G ++ V+APEH+ ++ + + +Q  AV +Y R    KS+  R   +K K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  301  GVFIGAYAKHPITGAPLPIWVSDYVIIGYGSGVVMGVPAHDERDREFANAFALPISEVLD  360
            GV  G+YA +P+ G  +P+W++DYV+ +YG+G +M+VPAHDERD+EFA+ F L I  VL+
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  361  DNG--QCIHSNHG-----DFLLNGLRGKEASDYVIAYLQKKNLGEGKVVYKLRDWLFSRQ  413
            +    +   +++G     DF L+GL    A   ++  L+   +G+ +V Y+LRDWLFSRQ
Sbjct  364  GGNVEEAAFTEDGLHINSDF-LDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQ  422

Query  414  RYWGEPIPIIHFEDGTCRpleddelpllppeIQDYRPKGFGQGPLANVKEWVEIHDVKTN  473
            RYWGEPIPIIH EDGT  ++ + ELPL+ P  +D RP G G++PLANV +W+E+      
Sbjct  423  RYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTR-EDG  481

Query  474  RKGRRETHTMPQWAGSCWYYLRFCDAHNSQAPWSNENERYWMPVDLYIGGAEHAVLHLLY  533
             KGRRET+TMPQWAGS WYYLR+ D+HN++    +E  + W+PVD+Y+GGAEHAVLHLLY
Sbjct  482  VKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLY  541

Query  534  SRFWHRVFYEAGLVSTPEPFKKLINQGLVLATSYRIPGKGYVHPEDVREDNGK-WTTASG  592
            +RFWH+V+Y+ G+V+T EPF+KL+NQG++L+TSYR +  + V  + V   +G      +G
Sbjct  542  ARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETG  601

Query  593  EELEVRQEKMSKSKLNGVDPQTLIDEFGADALRMYAMFSGPLDKNKLWCNHGVSGCRRFL  652
            EELE    KMSKS  N V+P+ +++++GAD+LR+Y MF GPLD +  W ++G+ G R+FL
Sbjct  602  EELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFL  661

Query  653  NRFYELVTSSAVQDVDDPKGMALAHKLVHRVGEDIEKMSLNTIPSSFMEFINEFTK----  708
            +R Y L+T+  + + +      + +  V  V E++++M +NT  + +M F+N   K    
Sbjct  662  DRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKL  721

Query  709  LDTYPKSALAMVVRALAPIAPHISEELWTIL-GYAPGIDKAEWPEVDPKYLEDASVTFVI  767
            +  Y+K+ + ++    AP+APH++EELW  L + + +I    WP  D   L +  V +V+
Sbjct  722  FSDYAKGFVQLI----APFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVV  777

Query  768  QVNGKLRARLDIDKNTSQEDI--LSAARESVAKYLEDKEIKKEVFVPNRLVNFVL  820
            Q++GK++A+L + K+ S+E++  ++ A E V   + +K+I K + VPN+LVN+V+
Sbjct  778  QIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

573) leuS in NC_018620


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  684 bits (2587),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 406/835 (49%), Positives = 597/835 (72%), Gaps = 23/835 (2%)

Query  3    YDPSLVEKKWQQFWKEHKSFKADETADKPKYYVLDMFPYPSGAGLHVGHLIGYTATDIVA  62
            YD + +E KWQ FW ++ +FK++  A KPK+Y LDMFPYPSGAGLHVGH  GYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRAKGFSVLHPMGWDSFGLPAEQYAVRTGTHPRETTKKNIENFRKQLSAMGFSYDEGR  122
            R+KRA+G +VLHPMGWD+FGLPAEQYA+ TG +P E T  NI NF++Q++A+GFSYD +R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EFATSDPDYYRWTQKLFLFLYEKGLAYMADMAVNYCEELGTVLANEEV-ENGLSVEGGYP  181
            E  T+DP+YY+WTQ +F  LYEKGLAY A+++VN  EELGT +ANEEV  +G S  GGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRMLRQWILRITAYSDQLLQGLEDLDWPENVKQLQRNWIGKSEGALVRFEV-DNGNFL  240
            V R+ +RQW+L+ITAY+++LL++LE++DWPE++K++QRNWIGKS GA V F V D ++ +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  SVFTTRPDTLCGVSFLVMAPEHPEINHLVSEEQHSAVENYIRCVQSKSERERISETKVKS  300
            +VFTTRPDTL G ++ V+APEH+ ++ + + +Q  AV +Y R    KS+  R   +K K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  301  GVFIGAYAKHPITGAPLPIWVSDYVIMGYGSGVVMGVPAHDERDREFANAFALPISEVLD  360
            GV  G+YA +P+ G  +P+W++DYV+ +YG+G +M+VPAHDERD+EFA+ F L I  VL+
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  361  DNG--QCIHSNHG-----DFLLNGLRGKEASDYVIAYLQKKNLGEGKVVYKLRDWLFSRQ  413
            +    +   +++G     DF L+GL    A   ++  L+   +G+ +V Y+LRDWLFSRQ
Sbjct  364  GGNVEEAAFTEDGLHINSDF-LDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQ  422

Query  414  RYWGEPIPIIHFEDGTCRpleddelpllppeIQDYRPKGFGQGPLANVKEWVEIHDVKTN  473
            RYWGEPIPIIH EDGT  ++ + ELPL+ P  +D RP G G++PLANV +W+E+      
Sbjct  423  RYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTR-EDG  481

Query  474  RKGRRETHTMPQWAGSCWYYLRFCDAHNSQAPWSNENERYWMPVDLYIGGAEHAVLHLLY  533
             KGRRET+TMPQWAGS WYYLR+ D+HN++    +E  + W+PVD+Y+GGAEHAVLHLLY
Sbjct  482  VKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLY  541

Query  534  SRFWHRVFYEAGLVSTPEPFKKLINQGLVLATSYRIPGKGYVHPEDVREDNGK-WTTASG  592
            +RFWH+V+Y+ G+V+T EPF+KL+NQG++L+TSYR +  + V  + V   +G      +G
Sbjct  542  ARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETG  601

Query  593  EELEVRQEKMSKSKLNGVDPQTLIDEFGADALRMYAMFSGPLDKNKLWCNHGVSGCRRFL  652
            EELE    KMSKS  N V+P+ +++++GAD+LR+Y MF GPLD +  W ++G+ G R+FL
Sbjct  602  EELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFL  661

Query  653  NRFYELVTSSAVQDVDDPKGMALAHKLVHRVGEDIEKMSLNTIPSSFMEFINEFTK----  708
            +R Y L+T+  + + +      + +  V  V E++++M +NT  + +M F+N   K    
Sbjct  662  DRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKL  721

Query  709  LDTYPKSALAMVVRALAPIAPHISEELWTIL-GYAPGIDKAEWPEVDPKYLEDASVTFVI  767
            +  Y+K+ + ++    AP+APH++EELW  L + + +I    WP  D   L +  V +V+
Sbjct  722  FSDYAKGFVQLI----APFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVV  777

Query  768  QVNGKLRARLDIDKNTSQEDI--LSAARESVAKYLEDKEIKKEVFVPNRLVNFVL  820
            Q++GK++A+L + K+ S+E++  ++ A E V   + +K+I K + VPN+LVN+V+
Sbjct  778  QIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

574) leuS in NC_018621


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  684 bits (2586),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 406/836 (49%), Positives = 595/836 (72%), Gaps = 25/836 (2%)

Query  3    YDPSLIEKKWQQFWKEHKSFKADETADKPKYYVLDMFPYPSGAGLHVGHLIGYTATDIVA  62
            YD + IE KWQ FW ++ +FK++  A KPK+Y LDMFPYPSGAGLHVGH  GYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRAKGFSVLHPMGWDSFGLPAEQYAVRTGTHPRETTKKNIENFRKQLSAMGFSYDERR  122
            R+KRA+G +VLHPMGWD+FGLPAEQYA+ TG +P E T  NI NF++Q++A+GFSYD  R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EFATSDPDYYRWTQKLFLFLYEKGLAYMADMAVNYCEELGTVLANEEV-ENGLSVEGGYP  181
            E  T+DP+YY+WTQ +F  LYEKGLAY A+++VN  EELGT +ANEEV  +G S  GGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRMLRQWILRITAYSDQLLQGLEDLDWPENVKQLQRNWIGKSEGALVRFEV-DNGNFL  240
            V R+ +RQW+L+ITAY+++LL++LE++DWPE++K++QRNWIGKS GA V F V D ++ +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  SVFTTRPDTLCGVSFLVMAPEHPEINHLVSEEQRSAVENYIRCVQSKSERERISETKVKS  300
            +VFTTRPDTL G ++ V+APEH+ ++ + + +Q  AV +Y R    KS+  R   +K K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  301  GVFIGAYAKHPITGAPLPIWVSDYVIMGYGSGVVMGVPAHDERDREFANAFALPISEVLD  360
            GV  G+YA +P+ G  +P+W++DYV+ +YG+G +M+VPAHDERD+EFA+ F L I  VL+
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  361  DNG--------QCIHSNHEDFLLNGLRGKEASDYVIAYLQKKNLGEAKVVYKLRDWLFSR  412
            +          + +H N +  +L+GL    A   ++  L+   +G+ +V Y+LRDWLFSR
Sbjct  364  GGNVEEAAFTEDGLHINSD--FLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSR  421

Query  413  QRYWGEPIPIIHFEDGTCRpleddelpllppeIQDYRPKGFGQGPLANVKEWVEIHDVKT  472
            QRYWGEPIPIIH EDGT  ++ + ELPL+ P  +D RP G G++PLANV +W+E+     
Sbjct  422  QRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTR-ED  480

Query  473  NRKGRRETHTMPQWAGSCWYYLRFCDAHNSQAPWSNENERYWMPVDLYIGGAEHAVLHLL  532
              KGRRET+TMPQWAGS WYYLR+ D+HN++    +E  + W+PVD+Y+GGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  533  YSRFWHRVFYEAGLVSTPEPFKKLINQGLVLATSYRIPGKGYVHPEDVREDNGK-WTTAS  591
            Y+RFWH+V+Y+ G+V+T EPF+KL+NQG++L+TSYR +  + V  + V   +G      +
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  592  GEELEVRQEKMSKSKLNGVDPQTLIDEFGADALRMYAMFSGPLDKNKLWCNHGVSGCRRF  651
            GEELE    KMSKS  N V+P+ +++++GAD+LR+Y MF GPLD +  W ++G+ G R+F
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  652  LNRFYELVTSSAVQDVDDPKGMALAHKLVHRVGEDIEKMSLNTIPSSFMEFINEFTK---  708
            L+R Y L+T+  + + +      + +  V  V E++++M +NT  + +M F+N   K   
Sbjct  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  709  -LDTYPKSALAMVVRALAPIAPHISEELWTIL-GYAPGIDKAGWPEVDPKYLEDASVTFV  766
             +  Y+K+ + ++    AP+APH++EELW  L + + +I    WP  D   L +  V +V
Sbjct  721  LFSDYAKGFVQLI----APFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  767  IQVNGKLRARLDIDKNTSQEDI--LSAARESVAKYLEDKEIKKEVFVPNRLVNFVL  820
            +Q++GK++A+L + K+ S+E++  ++ A E V   + +K+I K + VPN+LVN+V+
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

575) leuS in NC_017289


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  684 bits (2586),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 406/835 (49%), Positives = 597/835 (72%), Gaps = 23/835 (2%)

Query  3    YDPSLVEKKWQQFWKEHKSFKADETADKPKYYVLDMFPYPSGAGLHVGHLIGYTATDIVA  62
            YD + +E KWQ FW ++ +FK++  A KPK+Y LDMFPYPSGAGLHVGH  GYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRAKGFSVLHPMGWDSFGLPAEQYAVRTGTHPRETTKKNIENFRKQLSAMGFSYDEGR  122
            R+KRA+G +VLHPMGWD+FGLPAEQYA+ TG +P E T  NI NF++Q++A+GFSYD +R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EFATSDPDYYRWTQKLFLFLYEKGLAYMADMAVNYCEELGTVLANEEV-ENGLSVEGGYP  181
            E  T+DP+YY+WTQ +F  LYEKGLAY A+++VN  EELGT +ANEEV  +G S  GGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRMLRQWILRITAYSDQLLQGLEDLDWPENVKQLQRNWIGKSEGALVRFEV-DNGNFL  240
            V R+ +RQW+L+ITAY+++LL++LE++DWPE++K++QRNWIGKS GA V F V D ++ +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  SVFTTRPDTLCGVSFLVMAPEHPEINHLVSEEQRSAVENYIRCVQSKSERERISETKVKS  300
            +VFTTRPDTL G ++ V+APEH+ ++ + + +Q  AV +Y R    KS+  R   +K K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  301  GVFIGAYAKHPITGAPLPIWVSDYVIMGYGSGVVMGVPAHDERDREFANAFALPISEVLD  360
            GV  G+YA +P+ G  +P+W++DYV+ +YG+G +M+VPAHDERD+EFA+ F L I  VL+
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  361  DNG--QCIHSNHG-----DFLLNGLRGKEASDYVIAYLQKKNLGEGKVVYKLRDWLFSRQ  413
            +    +   +++G     DF L+GL    A   ++  L+   +G+ +V Y+LRDWLFSRQ
Sbjct  364  GGNVEEAAFTEDGLHINSDF-LDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQ  422

Query  414  RYWGEPIPIIHFEDGTCRpleddelpllppeIQDYRPKGFGQGPLANVKEWVEIHDVKTN  473
            RYWGEPIPIIH EDGT  ++ + ELPL+ P  +D RP G G++PLANV +W+E+      
Sbjct  423  RYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTR-EDG  481

Query  474  RKGRRETHTMPQWAGSCWYYLRFCDAHNSQAPWSNENERYWMPVDLYIGGAEHAVLHLLY  533
             KGRRET+TMPQWAGS WYYLR+ D+HN++    +E  + W+PVD+Y+GGAEHAVLHLLY
Sbjct  482  VKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLY  541

Query  534  SRFWHRVFYEAGLVSTPEPFKKLINQGLVLATSYRIPGKGYVHPEDVREDNGK-WTTASG  592
            +RFWH+V+Y+ G+V+T EPF+KL+NQG++L+TSYR +  + V  + V   +G      +G
Sbjct  542  ARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETG  601

Query  593  EELEVRQEKMSKSKLNGVDPQTLIDEFGADALRMYAMFSGPLDKNKLWCNHGVSGCRRFL  652
            EELE    KMSKS  N V+P+ +++++GAD+LR+Y MF GPLD +  W ++G+ G R+FL
Sbjct  602  EELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFL  661

Query  653  NRFYELVTSSAVQDVDDPKGMALAHKLVHRVGEDIEKMSLNTIPSSFMEFINEFTK----  708
            +R Y L+T+  + + +      + +  V  V E++++M +NT  + +M F+N   K    
Sbjct  662  DRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKL  721

Query  709  LDTYPKSALAMVVRALAPIAPHISEELWTIL-GYAPGIDKAEWPEVDPKYLEDASVTFVI  767
            +  Y+K+ + ++    AP+APH++EELW  L + + +I    WP  D   L +  V +V+
Sbjct  722  FSDYAKGFVQLI----APFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVV  777

Query  768  QVNGKLRARLDIDKNTSQEDI--LSAARESVAKYLEDKEIKKEVFVPNRLVNFVL  820
            Q++GK++A+L + K+ S+E++  ++ A E V   + +K+I K + VPN+LVN+V+
Sbjct  778  QIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

576) leuS in NC_017292


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  684 bits (2586),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 406/835 (49%), Positives = 597/835 (72%), Gaps = 23/835 (2%)

Query  3    YDPSLVEKKWQQFWKEHKSFKADETADKPKYYVLDMFPYPSGAGLHVGHLIGYTATDIVA  62
            YD + +E KWQ FW ++ +FK++  A KPK+Y LDMFPYPSGAGLHVGH  GYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRAKGFSVLHPMGWDSFGLPAEQYAVRTGTHPRETTKKNIENFRKQLSAMGFSYDEGR  122
            R+KRA+G +VLHPMGWD+FGLPAEQYA+ TG +P E T  NI NF++Q++A+GFSYD +R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EFATSDPDYYRWTQKLFLFLYEKGLAYMADMAVNYCEELGTVLANEEV-ENGLSVEGGYP  181
            E  T+DP+YY+WTQ +F  LYEKGLAY A+++VN  EELGT +ANEEV  +G S  GGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRMLRQWILRITAYSDQLLQGLEDLDWPENVKQLQRNWIGKSEGALVRFEV-DNGNFL  240
            V R+ +RQW+L+ITAY+++LL++LE++DWPE++K++QRNWIGKS GA V F V D ++ +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  SVFTTRPDTLCGVSFLVMAPEHPEINHLVSEEQRSAVENYIRCVQSKSERERISETKVKS  300
            +VFTTRPDTL G ++ V+APEH+ ++ + + +Q  AV +Y R    KS+  R   +K K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  301  GVFIGAYAKHPITGAPLPIWVSDYVIIGYGSGVVMGVPAHDERDREFANAFALPISEVLD  360
            GV  G+YA +P+ G  +P+W++DYV+ +YG+G +M+VPAHDERD+EFA+ F L I  VL+
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  361  DNG--QCIHSNHG-----DFLLNGLRGKEASDYVIAYLQKKNLGEGKVVYKLRDWLFSRQ  413
            +    +   +++G     DF L+GL    A   ++  L+   +G+ +V Y+LRDWLFSRQ
Sbjct  364  GGNVEEAAFTEDGLHINSDF-LDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQ  422

Query  414  RYWGEPIPIIHFEDGTCRpleddelpllppeIQDYRPKGFGQGPLANVKEWVEIHDVKTN  473
            RYWGEPIPIIH EDGT  ++ + ELPL+ P  +D RP G G++PLANV +W+E+      
Sbjct  423  RYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTR-EDG  481

Query  474  RKGRRETHTMPQWAGSCWYYLRFCDAHNSQAPWSNENERYWMPVDLYIGGAEHAVLHLLY  533
             KGRRET+TMPQWAGS WYYLR+ D+HN++    +E  + W+PVD+Y+GGAEHAVLHLLY
Sbjct  482  VKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLY  541

Query  534  SRFWHRVFYEAGLVSTPEPFKKLINQGLVLATSYRIPGKGYVHPEDVREDNGK-WTTASG  592
            +RFWH+V+Y+ G+V+T EPF+KL+NQG++L+TSYR +  + V  + V   +G      +G
Sbjct  542  ARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETG  601

Query  593  EELEVRQEKMSKSKLNGVDPQTLIDEFGADALRMYAMFSGPLDKNKLWCNHGVSGCRRFL  652
            EELE    KMSKS  N V+P+ +++++GAD+LR+Y MF GPLD +  W ++G+ G R+FL
Sbjct  602  EELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFL  661

Query  653  NRFYELVTSSAVQDVDDPKGMALAHKLVHRVGEDIEKMSLNTIPSSFMEFINEFTK----  708
            +R Y L+T+  + + +      + +  V  V E++++M +NT  + +M F+N   K    
Sbjct  662  DRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKL  721

Query  709  LDTYPKSALAMVVRALAPIAPHISEELWTIL-GYAPGIDKAEWPEVDPKYLEDASVTFVI  767
            +  Y+K+ + ++    AP+APH++EELW  L + + +I    WP  D   L +  V +V+
Sbjct  722  FSDYAKGFVQLI----APFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVV  777

Query  768  QVNGKLRARLDIDKNTSQEDI--LSAARESVAKYLEDKEIKKEVFVPNRLVNFVL  820
            Q++GK++A+L + K+ S+E++  ++ A E V   + +K+I K + VPN+LVN+V+
Sbjct  778  QIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

577) leuS in NC_017290


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  684 bits (2586),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 406/835 (49%), Positives = 597/835 (72%), Gaps = 23/835 (2%)

Query  3    YDPSLVEKKWQQFWKEHKSFKADETADKPKYYVLDMFPYPSGAGLHVGHLIGYTATDIVA  62
            YD + +E KWQ FW ++ +FK++  A KPK+Y LDMFPYPSGAGLHVGH  GYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRAKGFSVLHPMGWDSFGLPAEQYAVRTGTHPRETTKKNIENFRKQLSAMGFSYDEGR  122
            R+KRA+G +VLHPMGWD+FGLPAEQYA+ TG +P E T  NI NF++Q++A+GFSYD +R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EFATSDPDYYRWTQKLFLFLYEKGLAYMADMAVNYCEELGTVLANEEV-ENGLSVEGGYP  181
            E  T+DP+YY+WTQ +F  LYEKGLAY A+++VN  EELGT +ANEEV  +G S  GGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRMLRQWILRITAYSDQLLQGLEDLDWPENVKQLQRNWIGKSEGALVRFEV-DNGNFL  240
            V R+ +RQW+L+ITAY+++LL++LE++DWPE++K++QRNWIGKS GA V F V D ++ +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  SVFTTRPDTLCGVSFLVMAPEHPEINHLVSEEQRSAVENYIRCVQSKSERERISETKVKS  300
            +VFTTRPDTL G ++ V+APEH+ ++ + + +Q  AV +Y R    KS+  R   +K K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  301  GVFIGAYAKHPITGAPLPIWVSDYVIIGYGSGVVMGVPAHDERDREFANAFALPISEVLD  360
            GV  G+YA +P+ G  +P+W++DYV+ +YG+G +M+VPAHDERD+EFA+ F L I  VL+
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  361  DNG--QCIHSNHG-----DFLLNGLRGKEASDYVIAYLQKKNLGEGKVVYKLRDWLFSRQ  413
            +    +   +++G     DF L+GL    A   ++  L+   +G+ +V Y+LRDWLFSRQ
Sbjct  364  GGNVEEAAFTEDGLHINSDF-LDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQ  422

Query  414  RYWGEPIPIIHFEDGTCRpleddelpllppeIQDYRPKGFGQGPLANVKEWVEIHDVKTN  473
            RYWGEPIPIIH EDGT  ++ + ELPL+ P  +D RP G G++PLANV +W+E+      
Sbjct  423  RYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTR-EDG  481

Query  474  RKGRRETHTMPQWAGSCWYYLRFCDAHNSQAPWSNENERYWMPVDLYIGGAEHAVLHLLY  533
             KGRRET+TMPQWAGS WYYLR+ D+HN++    +E  + W+PVD+Y+GGAEHAVLHLLY
Sbjct  482  VKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLY  541

Query  534  SRFWHRVFYEAGLVSTPEPFKKLINQGLVLATSYRIPGKGYVHPEDVREDNGK-WTTASG  592
            +RFWH+V+Y+ G+V+T EPF+KL+NQG++L+TSYR +  + V  + V   +G      +G
Sbjct  542  ARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETG  601

Query  593  EELEVRQEKMSKSKLNGVDPQTLIDEFGADALRMYAMFSGPLDKNKLWCNHGVSGCRRFL  652
            EELE    KMSKS  N V+P+ +++++GAD+LR+Y MF GPLD +  W ++G+ G R+FL
Sbjct  602  EELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFL  661

Query  653  NRFYELVTSSAVQDVDDPKGMALAHKLVHRVGEDIEKMSLNTMPSSFMEFINEFTK----  708
            +R Y L+T+  + + +      + +  V  V E++++M +NT  + +M F+N   K    
Sbjct  662  DRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKL  721

Query  709  LDTYPKSALAMVVRALAPIAPHISEELWTIL-GYAPGIDKAEWPEVDPKYLEDASVTFVI  767
            +  Y+K+ + ++    AP+APH++EELW  L + + +I    WP  D   L +  V +V+
Sbjct  722  FSDYAKGFVQLI----APFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVV  777

Query  768  QVNGKLRARLDIDKNTSQEDI--LSAARESVAKYLEDKEIKKEVFVPNRLVNFVL  820
            Q++GK++A+L + K+ S+E++  ++ A E V   + +K+I K + VPN+LVN+V+
Sbjct  778  QIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

578) leuS in NC_017287


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  684 bits (2586),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 406/835 (49%), Positives = 597/835 (72%), Gaps = 23/835 (2%)

Query  3    YDPSLVEKKWQQFWKEHKSFKADETADKPKYYVLDMFPYPSGAGLHVGHLIGYTATDIVA  62
            YD + +E KWQ FW ++ +FK++  A KPK+Y LDMFPYPSGAGLHVGH  GYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRAKGFSVLHPMGWDSFGLPAEQYAVRTGTHPRETTKKNIENFRKQLSAMGFSYDEGR  122
            R+KRA+G +VLHPMGWD+FGLPAEQYA+ TG +P E T  NI NF++Q++A+GFSYD +R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EFATSDPDYYRWTQKLFLFLYEKGLAYMADMAVNYCEELGTVLANEEV-ENGLSVEGGYP  181
            E  T+DP+YY+WTQ +F  LYEKGLAY A+++VN  EELGT +ANEEV  +G S  GGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRMLRQWILRITAYSDQLLQGLEDLDWPENVKQLQRNWIGKSEGALVRFEV-DNGNFL  240
            V R+ +RQW+L+ITAY+++LL++LE++DWPE++K++QRNWIGKS GA V F V D ++ +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  SVFTTRPDTLCGVSFLVMAPEHPEINHLVSEEQRSAVENYIRCVQSKSERERISETKVKS  300
            +VFTTRPDTL G ++ V+APEH+ ++ + + +Q  AV +Y R    KS+  R   +K K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  301  GVFIGAYAKHPITGAPLPIWVSDYVIMGYGSGVVMGVPAHDERDREFANAFALPISEVLD  360
            GV  G+YA +P+ G  +P+W++DYV+ +YG+G +M+VPAHDERD+EFA+ F L I  VL+
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  361  DNG--QCIHSNHG-----DFLLNGLRGKEASDYVIAYLQKKNLGEGKVVYKLRDWLFSRQ  413
            +    +   +++G     DF L+GL    A   ++  L+   +G+ +V Y+LRDWLFSRQ
Sbjct  364  GGNVEEAAFTEDGLHINSDF-LDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQ  422

Query  414  RYWGEPIPIIHFEDGTCRpleddelpllppeIQDYRPKGFGQGPLANVKEWVEIHDVKTN  473
            RYWGEPIPIIH EDGT  ++ + ELPL+ P  +D RP G G++PLANV +W+E+      
Sbjct  423  RYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTR-EDG  481

Query  474  RKGRRETHTMPQWAGSCWYYLRFCDAHNSQAPWSNENERYWMPVDLYIGGAEHAVLHLLY  533
             KGRRET+TMPQWAGS WYYLR+ D+HN++    +E  + W+PVD+Y+GGAEHAVLHLLY
Sbjct  482  VKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLY  541

Query  534  SRFWHRVFYEAGLVSTPEPFKKLINQGLVLATSYRIPGKGYVHPEDVREDNGK-WTTASG  592
            +RFWH+V+Y+ G+V+T EPF+KL+NQG++L+TSYR +  + V  + V   +G      +G
Sbjct  542  ARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETG  601

Query  593  EELEVRQEKMSKSKLNGVDPQTLIDEFGADALRMYAMFSGPLDKNKLWCNHGVSGCRRFL  652
            EELE    KMSKS  N V+P+ +++++GAD+LR+Y MF GPLD +  W ++G+ G R+FL
Sbjct  602  EELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFL  661

Query  653  NRFYELVTSSAVQDVDDPKGMALAHKLVHRVGEDIEKMSLNTIPSSFMEFINEFTK----  708
            +R Y L+T+  + + +      + +  V  V E++++M +NT  + +M F+N   K    
Sbjct  662  DRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKL  721

Query  709  LDTYPKSALAMVVRALAPIAPHISEELWTIL-GYAPGIDKAEWPEVDPKYLEDASVTFVI  767
            +  Y+K+ + ++    AP+APH++EELW  L + + +I    WP  D   L +  V +V+
Sbjct  722  FSDYAKGFVQLI----APFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVV  777

Query  768  QVNGKLRARLDIDKNTSQEDI--LSAARESVAKYLEDKEIKKEVFVPNRLVNFVL  820
            Q++GK++A+L + K+ S+E++  ++ A E V   + +K+I K + VPN+LVN+V+
Sbjct  778  QIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

579) leuS in NC_015470


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  684 bits (2586),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 406/835 (49%), Positives = 597/835 (72%), Gaps = 23/835 (2%)

Query  3    YDPSLVEKKWQQFWKEHKSFKADETADKPKYYVLDMFPYPSGAGLHVGHLIGYTATDIVA  62
            YD + +E KWQ FW ++ +FK++  A KPK+Y LDMFPYPSGAGLHVGH  GYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRAKGFSVLHPMGWDSFGLPAEQYAVRTGTHPRETTKKNIENFRKQLSAMGFSYDEGR  122
            R+KRA+G +VLHPMGWD+FGLPAEQYA+ TG +P E T  NI NF++Q++A+GFSYD +R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EFATSDPDYYRWTQKLFLFLYEKGLAYMADMAVNYCEELGTVLANEEV-ENGLSVEGGYP  181
            E  T+DP+YY+WTQ +F  LYEKGLAY A+++VN  EELGT +ANEEV  +G S  GGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRMLRQWILRITAYSDQLLQGLEDLDWPENVKQLQRNWIGKSEGALVRFEV-DNGNFL  240
            V R+ +RQW+L+ITAY+++LL++LE++DWPE++K++QRNWIGKS GA V F V D ++ +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  SVFTTRPDTLCGVSFLVMAPEHPEINHLVSEEQRSAVENYIRCVQSKSERERISETKVKS  300
            +VFTTRPDTL G ++ V+APEH+ ++ + + +Q  AV +Y R    KS+  R   +K K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  301  GVFIGAYAKHPITGAPLPIWVSDYVIMGYGSGVVMGVPAHDERDREFANAFALPISEVLD  360
            GV  G+YA +P+ G  +P+W++DYV+ +YG+G +M+VPAHDERD+EFA+ F L I  VL+
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  361  DNG--QCIHSNHG-----DFLLNGLRGKEASDYVIAYLQKKNLGEGKVVYKLRDWLFSRQ  413
            +    +   +++G     DF L+GL    A   ++  L+   +G+ +V Y+LRDWLFSRQ
Sbjct  364  GGNVEEAAFTEDGLHINSDF-LDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQ  422

Query  414  RYWGEPIPIIHFEDGTCRpleddelpllppeIQDYRPKGFGQGPLANVKEWVEIHDVKTN  473
            RYWGEPIPIIH EDGT  ++ + ELPL+ P  +D RP G G++PLANV +W+E+      
Sbjct  423  RYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTR-EDG  481

Query  474  RKGRRETHTMPQWAGSCWYYLRFCDAHNSQAPWSNENERYWMPVDLYIGGAEHAVLHLLY  533
             KGRRET+TMPQWAGS WYYLR+ D+HN++    +E  + W+PVD+Y+GGAEHAVLHLLY
Sbjct  482  VKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLY  541

Query  534  SRFWHRVFYEAGLVSTPEPFKKLINQGLVLATSYRIPGKGYVHPEDVREDNGK-WTTASG  592
            +RFWH+V+Y+ G+V+T EPF+KL+NQG++L+TSYR +  + V  + V   +G      +G
Sbjct  542  ARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETG  601

Query  593  EELEVRQEKMSKSKLNGVDPQTLIDEFGADALRMYAMFSGPLDKNKLWCNHGVSGCRRFL  652
            EELE    KMSKS  N V+P+ +++++GAD+LR+Y MF GPLD +  W ++G+ G R+FL
Sbjct  602  EELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFL  661

Query  653  NRFYELVTSSAVQDVDDPKGMALAHKLVHRVGEDIEKMSLNTIPSSFMEFINEFTK----  708
            +R Y L+T+  + + +      + +  V  V E++++M +NT  + +M F+N   K    
Sbjct  662  DRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKL  721

Query  709  LDTYPKSALAMVVRALAPIAPHISEELWTIL-GYAPGIDKAEWPEVDPKYLEDASVTFVI  767
            +  Y+K+ + ++    AP+APH++EELW  L + + +I    WP  D   L +  V +V+
Sbjct  722  FSDYAKGFVQLI----APFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVV  777

Query  768  QVNGKLRARLDIDKNTSQEDI--LSAARESVAKYLEDKEIKKEVFVPNRLVNFVL  820
            Q++GK++A+L + K+ S+E++  ++ A E V   + +K+I K + VPN+LVN+V+
Sbjct  778  QIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

580) leuS in NC_017291


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  684 bits (2586),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 406/835 (49%), Positives = 597/835 (72%), Gaps = 23/835 (2%)

Query  3    YDPSLVEKKWQQFWKEHKSFKADETADKPKYYVLDMFPYPSGAGLHVGHLIGYTATDIVA  62
            YD + +E KWQ FW ++ +FK++  A KPK+Y LDMFPYPSGAGLHVGH  GYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRAKGFSVLHPMGWDSFGLPAEQYAVRTGTHPRETTKKNIENFRKQLSAMGFSYDEGR  122
            R+KRA+G +VLHPMGWD+FGLPAEQYA+ TG +P E T  NI NF++Q++A+GFSYD +R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EFATSDPDYYRWTQKLFLFLYEKGLAYMADMAVNYCEELGTVLANEEV-ENGLSVEGGYP  181
            E  T+DP+YY+WTQ +F  LYEKGLAY A+++VN  EELGT +ANEEV  +G S  GGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRMLRQWILRITAYSDQLLQGLEDLDWPENVKQLQRNWIGKSEGALVRFEV-DNGNFL  240
            V R+ +RQW+L+ITAY+++LL++LE++DWPE++K++QRNWIGKS GA V F V D ++ +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  SVFTTRPDTLCGVSFLVMAPEHPEINHLVSEEQRSAVENYIRCVQSKSERERISETKVKS  300
            +VFTTRPDTL G ++ V+APEH+ ++ + + +Q  AV +Y R    KS+  R   +K K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  301  GVFIGAYAKHPITGAPLPIWVSDYVIMGYGSGVVMGVPAHDERDREFANAFALPISEVLD  360
            GV  G+YA +P+ G  +P+W++DYV+ +YG+G +M+VPAHDERD+EFA+ F L I  VL+
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  361  DNG--QCIHSNHG-----DFLLNGLRGKEASDYVIAYLQKKNLGEGKVVYKLRDWLFSRQ  413
            +    +   +++G     DF L+GL    A   ++  L+   +G+ +V Y+LRDWLFSRQ
Sbjct  364  GGNVEEAAFTEDGLHINSDF-LDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQ  422

Query  414  RYWGEPIPIIHFEDGTCRpleddelpllppeIQDYRPKGFGQGPLANVKEWVEIHDVKTN  473
            RYWGEPIPIIH EDGT  ++ + ELPL+ P  +D RP G G++PLANV +W+E+      
Sbjct  423  RYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTR-EDG  481

Query  474  RKGRRETHTMPQWAGSCWYYLRFCDAHNSQAPWSNENERYWMPVDLYIGGAEHAVLHLLY  533
             KGRRET+TMPQWAGS WYYLR+ D+HN++    +E  + W+PVD+Y+GGAEHAVLHLLY
Sbjct  482  VKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLY  541

Query  534  SRFWHRVFYEAGLVSTPEPFKKLINQGLVLATSYRIPGKGYVHPEDVREDNGK-WTTASG  592
            +RFWH+V+Y+ G+V+T EPF+KL+NQG++L+TSYR +  + V  + V   +G      +G
Sbjct  542  ARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETG  601

Query  593  EELEVRQEKMSKSKLNGVDPQTLIDEFGADALRMYAMFSGPLDKNKLWCNHGVSGCRRFL  652
            EELE    KMSKS  N V+P+ +++++GAD+LR+Y MF GPLD +  W ++G+ G R+FL
Sbjct  602  EELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFL  661

Query  653  NRFYELVTSSAVQDVDDPKGMALAHKLVHRVGEDIEKMSLNTIPSSFMEFINEFTK----  708
            +R Y L+T+  + + +      + +  V  V E++++M +NT  + +M F+N   K    
Sbjct  662  DRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKL  721

Query  709  LDTYPKSALAMVVRALAPIAPHISEELWTIL-GYAPGIDKAEWPEVDPKYLEDASVTFVI  767
            +  Y+K+ + ++    AP+APH++EELW  L + + +I    WP  D   L +  V +V+
Sbjct  722  FSDYAKGFVQLI----APFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVV  777

Query  768  QVNGKLRARLDIDKNTSQEDI--LSAARESVAKYLEDKEIKKEVFVPNRLVNFVL  820
            Q++GK++A+L + K+ S+E++  ++ A E V   + +K+I K + VPN+LVN+V+
Sbjct  778  QIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

581) leuS in NC_014796


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  684 bits (2586),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 406/835 (49%), Positives = 597/835 (72%), Gaps = 23/835 (2%)

Query  3    YDPSLVEKKWQQFWKEHKSFKADETADKPKYYVLDMFPYPSGAGLHVGHLIGYTATDIVA  62
            YD + +E KWQ FW ++ +FK++  A KPK+Y LDMFPYPSGAGLHVGH  GYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRAKGFSVLHPMGWDSFGLPAEQYAVRTGTHPRETTKKNIENFRKQLSAMGFSYDEGR  122
            R+KRA+G +VLHPMGWD+FGLPAEQYA+ TG +P E T  NI NF++Q++A+GFSYD +R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EFATSDPDYYRWTQKLFLFLYEKGLAYMADMAVNYCEELGTVLANEEV-ENGLSVEGGYP  181
            E  T+DP+YY+WTQ +F  LYEKGLAY A+++VN  EELGT +ANEEV  +G S  GGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRMLRQWILRITAYSDQLLQGLEDLDWPENVKQLQRNWIGKSEGALVRFEV-DNGNFL  240
            V R+ +RQW+L+ITAY+++LL++LE++DWPE++K++QRNWIGKS GA V F V D ++ +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  SVFTTRPDTLCGVSFLVMAPEHPEINHLVSEEQRSAVENYIRCVQSKSERERISETKVKS  300
            +VFTTRPDTL G ++ V+APEH+ ++ + + +Q  AV +Y R    KS+  R   +K K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  301  GVFIGAYAKHPITGAPLPIWVSDYVIMGYGSGVVMGVPAHDERDREFANAFALPISEVLD  360
            GV  G+YA +P+ G  +P+W++DYV+ +YG+G +M+VPAHDERD+EFA+ F L I  VL+
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  361  DNG--QCIHSNHG-----DFLLNGLRGKEASDYVIAYLQKKNLGEGKVVYKLRDWLFSRQ  413
            +    +   +++G     DF L+GL    A   ++  L+   +G+ +V Y+LRDWLFSRQ
Sbjct  364  GGNVEEAAFTEDGLHINSDF-LDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQ  422

Query  414  RYWGEPIPIIHFEDGTCRpleddelpllppeIQDYRPKGFGQGPLANVKEWVEIHDVKTN  473
            RYWGEPIPIIH EDGT  ++ + ELPL+ P  +D RP G G++PLANV +W+E+      
Sbjct  423  RYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTR-EDG  481

Query  474  RKGRRETHTMPQWAGSCWYYLRFCDAHNSQAPWSNENERYWMPVDLYIGGAEHAVLHLLY  533
             KGRRET+TMPQWAGS WYYLR+ D+HN++    +E  + W+PVD+Y+GGAEHAVLHLLY
Sbjct  482  VKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLY  541

Query  534  SRFWHRVFYEAGLVSTPEPFKKLINQGLVLATSYRIPGKGYVHPEDVREDNGK-WTTASG  592
            +RFWH+V+Y+ G+V+T EPF+KL+NQG++L+TSYR +  + V  + V   +G      +G
Sbjct  542  ARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETG  601

Query  593  EELEVRQEKMSKSKLNGVDPQTLIDEFGADALRMYAMFSGPLDKNKLWCNHGVSGCRRFL  652
            EELE    KMSKS  N V+P+ +++++GAD+LR+Y MF GPLD +  W ++G+ G R+FL
Sbjct  602  EELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFL  661

Query  653  NRFYELVTSSAVQDVDDPKGMALAHKLVHRVGEDIEKMSLNTIPSSFMEFINEFTK----  708
            +R Y L+T+  + + +      + +  V  V E++++M +NT  + +M F+N   K    
Sbjct  662  DRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKL  721

Query  709  LDTYPKSALAMVVRALAPIAPHISEELWTIL-GYAPGIDKAEWPEVDPKYLEDASVTFVI  767
            +  Y+K+ + ++    AP+APH++EELW  L + + +I    WP  D   L +  V +V+
Sbjct  722  FSDYAKGFVQLI----APFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVV  777

Query  768  QVNGKLRARLDIDKNTSQEDI--LSAARESVAKYLEDKEIKKEVFVPNRLVNFVL  820
            Q++GK++A+L + K+ S+E++  ++ A E V   + +K+I K + VPN+LVN+V+
Sbjct  778  QIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

582) Bd0365 in NC_005363


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  683 bits (2582),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 409/812 (51%), Positives = 570/812 (71%), Gaps = 46/812 (5%)

Query  26   TTSSKPKYYALDMFPYPSASGLHVGHMASYTPGDIISRYKRVNGFNVLHPMGYDAFGLPA  85
            T +SKPK+YALDMFPYPS++GLHVGH  +YT+ DI+SR+KR +G NVLHPMG DAFGLPA
Sbjct  27   TDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSRFKRAQGHNVLHPMGWDAFGLPA  86

Query  86   EQYAIQTGVHPAITTKKAIDSFRKTLQTFGFSFDWSREISTCEPDYYKWTQFIFLKLYER  145
            EQYA++TG +PA  T   I +F++ ++++GFS+DW RE++T +P+YYKWTQ IF KLYE+
Sbjct  87   EQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEK  146

Query  146  GLAYQKEVPVNWCPALKTVLANDEVV-DGKSERGGHPVIRVPMKQWMLKITDYAERLLND  204
            GLAY+ EVPVNW   L T +AN+EV+ DG SERGG PV+R PM+QWMLKIT YAERLL+D
Sbjct  147  GLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLED  206

Query  205  LDKLDWPERTKEGQRNWIGKSEGARITFKVHGEKDTFEVFTTRPDTLFGVTFMVMAPEHP  264
            L+ +DWPE  K+ QRNWIGKS GA +TFKV +    F VFTTRPDTLFG T+ V+APEH+
Sbjct  207  LEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHA  266

Query  265  LVKKITSQPQYTAVENYIADTAKKSEVDRKA-STEKTGVFTGAHATHPITGDKIEIWISD  323
            LV  IT+  Q  AV +Y  +++ KS++ R   + EKTGV TG+ A +P+ G  + +WI+D
Sbjct  267  LVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAINPVNGKEMPVWIAD  326

Query  324  YVLMDYGTGAIMAVPGHDARDFEFATKFNIPIKSVLESDML---PFEGDSIMINSEFLDG  380
            YVL  YGTGAIMAVP+HD RD EFA +FN+ I +VLE++ +   +F  D++ INS+FLDG
Sbjct  327  YVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEAAFTEDGLHINSDFLDG  386

Query  381  LNKTEAISKMLKHLEENKLGVREVQYKLRDWLFSRQRYWGEPFPIVHFADG-SKGVPVNE  439
            L+K+ AI+KM+  LE + +G  +V Y+LRDWLFSRQRYWGEP+PI+H  DG S +VP +E
Sbjct  387  LDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESE  446

Query  440  LPVILPEVADYEPADTGEAPLARNADWVKYM-DGDKEGRRETDTMPGAAGSSWYFLRYID  498
            LP++LP   D  P++TGE+PLA  +DW+    +++  GRRET+TMP  AGSSWY+LRYID
Sbjct  447  LPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYID  506

Query  499  PKNTEAPFSPEAEKYWMPVDLYVGGPEHTVGHLLYARFWTKVLFDCGLVTHDEPFQKLAH  558
            P NTE     E  K W+PVD+YVGG+EH+V HLLYARFW KVL+D G+V   EPFQKL +
Sbjct  507  PHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFN  566

Query  559  QGMILGPD---------------------------------GEKMSKSRGNVISPEDIAR  585
            QGMILG                                     KMSKS  NV++P+D+  
Sbjct  567  QGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVE  626

Query  586  SHGADALRTFISFMGPVDKDKPWAPTGIDGVKRFLDRITRLVVNDDGQLVATSEALTPEI  645
              GAD+LR +  FMGP+D   +W+  G++G ++FLDR+ RL+   +      +E  +  +
Sbjct  627  QYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKE-----ITEENSGAL  681

Query  646  EKLVHKTIKKVTEDIESMSFNTAISAMMILVNELYRAECRSVLAVKPLVQILAPFAPHLA  705
            +K+ + T+K VTE+++ M FNTAI+ +M++VN   + +       K +VQ++APFAPHL+
Sbjct  682  DKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLG  741

Query  706  EELWEKMNGEGLC-ALAPWPKYDNTLCADDTVTIGVQVNGKMRGTIEIGvaaseqeavaa  764
            EELW+ + + G   +  PWP YD++   ++ V I VQ++GK+++ + ++   S +E    
Sbjct  742  EELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEV  801

Query  765  akavqqvaavLGDKNPDKVIYKAGKILNLIVK  796
            A A ++V A +++K+  KVI  + K++N+++K
Sbjct  802  ALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

583) Oter_3868 in NC_010571


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  683 bits (2581),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 446/884 (51%), Positives = 600/884 (68%), Gaps = 91/884 (10%)

Query  8    YNFQEIEPHWQSFWEQHRSFRAENGSSKPKFYVLDMFPYPSGAGLHIGHPEGYTATDILA  67
            Y+   IEP WQ+FW ++++F++  ++SKPKFY LDMFPYPSGAGLH+GHPEGYTATDIL+
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  68   RAKRAQGFNVLHPIGWDAFGLPAEQHAVKTGTHPATNTQNNITNFRRQIKALGFSYDWER  127
            R KRAQG NVLHP+GWDAFGLPAEQ A+ TG +PA  T +NI+NF+RQI+ALGFSYDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  128  EIDTTDPKYFRWTQWIFLQLFKRGLAYVDERPVWWCPELRTVLANEEVV-DGKSEVGGFP  186
            E++TTDP+Y++WTQWIF +L+ +GLAY  E PV W  EL T +ANEEV+ DG SE GG+P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  187  VERRNLRQWVLRITAYAERLLADLKTVNWPESTKRMQEAWIGRSEGAELLFELEHKSLGQ  246
            V R+ +RQW+L+ITAYAERLL DL  V+WPES K MQ  WIG+S GA++ F + +    +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD-KD  242

Query  247  LKVFTTRPDTLFGCTYMVVAPEHPLVARLTTPDHRaaveaykkkaaakSDLERTDLAKGK  306
            + VFTTRPDTLFG TY V+APEH+LV  +TT+D+  AV  YK++A+ KSDL RTDLAK K
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEK  302

Query  307  SGVFSGSYAINPINGERVPIWIADYVLMGYGTGAIMAVPAHDERDYEFAQQYDLPITRVI  366
            +GV +GSYAINP+NG  +P+WIADYVL +YGTGAIMAVPAHDERD EFA+Q++L I  V+
Sbjct  303  TGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL  362

Query  367  ANDDGGDRLPFTGDGHLVNSGPYDGLRWEEAKKRITAELAQRGVGQATVNYKLRDWLFSR  426
              ++  +  +FT DG  +NS+  DGL    A  ++   L   GVG+  V Y+LRDWLFSR
Sbjct  363  EGGNVEEA-AFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSR  421

Query  427  QRYWGEPFPVA-WvdeadyrraaaarpadvppnpvTFTSNGVTHYalplpaaalplelpD  485
            QRYWGEP+P+  W                          +G +        + +     D
Sbjct  422  QRYWGEPIPIIHW-------------------------EDGTSTAVPESELPLVLPVTKD  456

Query  486  VQSYLPSGNGESPLANVTDWLEIWLDYTNGAAVPASQPRPAGDTWIRARRETNTMPQWAG  545
            ++   PSG GESPLANVTDWLE+               R  G   +++RRETNTMPQWAG
Sbjct  457  IR---PSGTGESPLANVTDWLEV--------------TREDG---VKGRRETNTMPQWAG  496

Query  546  SCWYYLRFLDPKNPDAIASPEALRYWGVPDLYVGGAEHAVLHLLYARFWHKVLFDLGVVP  605
            S WYYLR++DP N + +A  E L+ W   D+YVGGAEHAVLHLLYARFWHKVL+DLGVVP
Sbjct  497  SSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVP  556

Query  606  QSEPFTRLFHQGIILG---------------------------------EDGEKMSKSRG  632
              EPF +LF+QG+ILG                                 +   KMSKS  
Sbjct  557  TKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLK  616

Query  633  NVVNPDTIIASHGTDTLRLYLMFLGPLEAMKPWSMQQIEGVHRFLQKVWRECIGPDGKVN  692
            NVVNPD ++   G+DTLR+Y MF+GPL+A  +WS + +EG ++FL++V R     +    
Sbjct  617  NVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKE----  672

Query  693  PKISAQAAEPAEVIKVLHETIKKVGEDIEALRFNTAISQMMICANALQKSPQVSRSTMLS  752
              I+ + + + +  KV +ET+K V E+++ ++FNTAI+Q+M+  NA +K  ++      +
Sbjct  673  --ITEENSGALD--KVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKG  728

Query  753  FLQLLAPFAPHLAEELWQRL-GESPSIQAAPWPKYDASKLATGQVKLVFQVNGKHRGDAL  811
            F+QL+APFAPHL+EELWQ L + + SI   PWP YD SKL   +V +V Q++GK ++  +
Sbjct  729  FVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLV  788

Query  812  VPVGLSQadavaaatahekvaPFVTGRTVKRVVYVPGKILNIVV  855
            V+ +LS+ +    A A+EKV + ++G+ + +V+ VP K++NIV+
Sbjct  789  VAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

584) leuS in NC_010287


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  683 bits (2582),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 414/834 (50%), Positives = 598/834 (72%), Gaps = 22/834 (2%)

Query  3    YDPGLIEEKWQKFWKNEQVFKAEEDETKTKYYVLDMFPYPSGAGLHVGHLIGYTATDIVA  62
            YD   IE KWQ FW +++ FK+  D +K K+Y LDMFPYPSGAGLHVGH  GYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RCKRAQGFSVLHPMGWDSFGLPAEQYAIRTGTHPRETTEKNIANFKKQLTAMGFSYDESR  122
            R KRAQG +VLHPMGWD+FGLPAEQYA+ TG +P E T  NIANFK+Q+ A+GFSYD  R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EFATSDPEYYKWTQKLFLILYEKGLAYMADMAVNYCPELGTVLSNEEI-ENGFSVDGGYP  181
            E  T+DP+YYKWTQ +F  LYEKGLAY A+++VN   ELGT ++NEE+  +G S  GGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRMLRQWVLRITAFADQLLEGLDELDWPESVKQLQKNWIGKSSGASVNFATEHGAIE-  240
            V R+ +RQW+L+ITA+A++LLE+L+E+DWPES+K++Q+NWIGKS+GA+V F   +   + 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  -VFTTRPDTLIGVSFLALAPEHPLVDLLTSDEQKAVVAQYIKETQSKSERDRISEMKTKS  299
             VFTTRPDTL+G ++  LAPEH+LVD +T+ +Q   VA+Y +++  KS+  R    K K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  300  GVFTGSYAKHPVTHELIPIWIADYVLMGFGSGAVMGVPAHDERDLLFAEQFNLPVVSVLN  359
            GV TGSYA +PV    +P+WIADYVL ++G+GA+M+VPAHDERD  FA QFNL +++VL+
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  360  EEGVCINSCCE-GFH-----LDGLSGEEAKQYVINFLEENHLGAAKIAYKLRDWLFSRQR  413
               V   +  E G+H     LDGL    A   +++ LE + +G  +++Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  414  YWGEPIPIIHFEDGSCrplrddelpllppeIQDYRPEGVGQGPLAKVREWVQVFDTETQR  473
            YWGEPIPIIH EDG+  ++ + ELPL+ P  +D RP G G++PLA+V +W++V   +  +
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  474  AGKRETHTMPQWAGSCWYYLRFCDAHNSAAPWAKEKEQYWMPVDLYIGGAEHAVLHLLYA  533
             G+RET+TMPQWAGS WYYLR+ D+HN+      E  + W+PVD+Y+GGAEHAVLHLLYA
Sbjct  484  -GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  534  RFWHQVFYEAGIVSTPEPFKKLVNQGLVLATSYRIPGKGYIYPETAKEENGK-WVAPSGE  592
            RFWH+V+Y+ G+V+T EPF+KL NQG++L+TSYR +  + +  +     +G      +GE
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  593  ELDVRQEKMSKSKLNGVDPQILIDEFGADAVRMYAMFSGPLDKNKLWSNQGVAGCRRFLN  652
            EL+    KMSKS  N V+P+ +++++GAD++R+Y MF GPLD +  WS++G+ G R+FL+
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  653  RFYEMVSSDRVKEDNNFEGLSLAHKLVQRVTDAIEKLSLNTIPSSFMEFINDFVK----L  708
            R Y ++++  + E+N+     + +  V+ VT+ ++++ +NT  + +M F+N   K    +
Sbjct  663  RVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLF  722

Query  709  AVYPKSAVEMAVRALAPIAPHISEELW-VLLGNSPGVQKSGWPSVLPEYLEEQTVTIVVQ  767
            + Y+K+ V++    +AP+APH++EELW  L +++ ++    WPS     L E+ V IVVQ
Sbjct  723  SDYAKGFVQL----IAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQ  778

Query  768  VNGKLRARLDIMKDASKEEV--LALARESASKYLEGCEVKKAIFVPARLVNFVV  819
            ++GK++A+L + KD S+EE+  +ALA E     + G ++ K I VP +LVN+V+
Sbjct  779  IKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

585) L1115_00212 in NC_020929


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  683 bits (2582),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 414/834 (50%), Positives = 598/834 (72%), Gaps = 22/834 (2%)

Query  3    YDPGLIEEKWQKFWKNEQVFKAEEDETKTKYYVLDMFPYPSGAGLHVGHLIGYTATDIVA  62
            YD   IE KWQ FW +++ FK+  D +K K+Y LDMFPYPSGAGLHVGH  GYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RCKRAQGFSVLHPMGWDSFGLPAEQYAIRTGTHPRETTEKNIANFKKQLTAMGFSYDESR  122
            R KRAQG +VLHPMGWD+FGLPAEQYA+ TG +P E T  NIANFK+Q+ A+GFSYD  R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EFATSDPEYYKWTQKLFLILYEKGLAYMADMAVNYCPELGTVLSNEEI-ENGFSVDGGYP  181
            E  T+DP+YYKWTQ +F  LYEKGLAY A+++VN   ELGT ++NEE+  +G S  GGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRMLRQWVLRITAFADQLLEGLDELDWPESVKQLQKNWIGKSSGASVNFATEHGAIE-  240
            V R+ +RQW+L+ITA+A++LLE+L+E+DWPES+K++Q+NWIGKS+GA+V F   +   + 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  -VFTTRPDTLIGVSFLALAPEHPLVDLLTSDEQKAVVAQYIKETQSKSERDRISEMKTKS  299
             VFTTRPDTL+G ++  LAPEH+LVD +T+ +Q   VA+Y +++  KS+  R    K K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  300  GVFTGSYAKHPVTHELIPIWIADYVLMGFGSGAVMGVPAHDERDLLFAEQFNLPVVSVLN  359
            GV TGSYA +PV    +P+WIADYVL ++G+GA+M+VPAHDERD  FA QFNL +++VL+
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  360  EEGVCINSCCE-GFH-----LDGLSGEEAKQYVINFLEENHLGAAKIAYKLRDWLFSRQR  413
               V   +  E G+H     LDGL    A   +++ LE + +G  +++Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  414  YWGEPIPIIHFEDGSCrplrddelpllppeIQDYRPEGVGQGPLAKVREWVQVFDTETQR  473
            YWGEPIPIIH EDG+  ++ + ELPL+ P  +D RP G G++PLA+V +W++V   +  +
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  474  AGKRETHTMPQWAGSCWYYLRFCDAHNSAAPWAKEKEQYWMPVDLYIGGAEHAVLHLLYA  533
             G+RET+TMPQWAGS WYYLR+ D+HN+      E  + W+PVD+Y+GGAEHAVLHLLYA
Sbjct  484  -GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  534  RFWHQVFYEAGIVSTPEPFKKLVNQGLVLATSYRIPGKGYIYPETAKEENGK-WVAPSGE  592
            RFWH+V+Y+ G+V+T EPF+KL NQG++L+TSYR +  + +  +     +G      +GE
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  593  ELDVRQEKMSKSKLNGVDPQILIDEFGADAVRMYAMFSGPLDKNKLWSNQGVAGCRRFLN  652
            EL+    KMSKS  N V+P+ +++++GAD++R+Y MF GPLD +  WS++G+ G R+FL+
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  653  RFYEMVSSDRVKEDNNFEGLSLAHKLVQRVTDAIEKLSLNTIPSSFMEFINDFVK----L  708
            R Y ++++  + E+N+     + +  V+ VT+ ++++ +NT  + +M F+N   K    +
Sbjct  663  RVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLF  722

Query  709  AVYPKSAVEMAVRALAPIAPHISEELW-VLLGNSPGVQKSGWPSVLPEYLEEQTVTIVVQ  767
            + Y+K+ V++    +AP+APH++EELW  L +++ ++    WPS     L E+ V IVVQ
Sbjct  723  SDYAKGFVQL----IAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQ  778

Query  768  VNGKLRARLDIMKDASKEEV--LALARESASKYLEGCEVKKAIFVPARLVNFVV  819
            ++GK++A+L + KD S+EE+  +ALA E     + G ++ K I VP +LVN+V+
Sbjct  779  IKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

586) L1224_00212 in NC_020973


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  683 bits (2582),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 414/834 (50%), Positives = 598/834 (72%), Gaps = 22/834 (2%)

Query  3    YDPGLIEEKWQKFWKNEQVFKAEEDETKTKYYVLDMFPYPSGAGLHVGHLIGYTATDIVA  62
            YD   IE KWQ FW +++ FK+  D +K K+Y LDMFPYPSGAGLHVGH  GYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RCKRAQGFSVLHPMGWDSFGLPAEQYAIRTGTHPRETTEKNIANFKKQLTAMGFSYDESR  122
            R KRAQG +VLHPMGWD+FGLPAEQYA+ TG +P E T  NIANFK+Q+ A+GFSYD  R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EFATSDPEYYKWTQKLFLILYEKGLAYMADMAVNYCPELGTVLSNEEI-ENGFSVDGGYP  181
            E  T+DP+YYKWTQ +F  LYEKGLAY A+++VN   ELGT ++NEE+  +G S  GGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRMLRQWVLRITAFADQLLEGLDELDWPESVKQLQKNWIGKSSGASVNFATEHGAIE-  240
            V R+ +RQW+L+ITA+A++LLE+L+E+DWPES+K++Q+NWIGKS+GA+V F   +   + 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  -VFTTRPDTLIGVSFLALAPEHPLVDLLTSDEQKAVVAQYIKETQSKSERDRISEMKTKS  299
             VFTTRPDTL+G ++  LAPEH+LVD +T+ +Q   VA+Y +++  KS+  R    K K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  300  GVFTGSYAKHPVTHELIPIWIADYVLMGFGSGAVMGVPAHDERDLLFAEQFNLPVVSVLN  359
            GV TGSYA +PV    +P+WIADYVL ++G+GA+M+VPAHDERD  FA QFNL +++VL+
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  360  EEGVCINSCCE-GFH-----LDGLSGEEAKQYVINFLEENHLGAAKIAYKLRDWLFSRQR  413
               V   +  E G+H     LDGL    A   +++ LE + +G  +++Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  414  YWGEPIPIIHFEDGSCrplrddelpllppeIQDYRPEGVGQGPLAKVREWVQVFDTETQR  473
            YWGEPIPIIH EDG+  ++ + ELPL+ P  +D RP G G++PLA+V +W++V   +  +
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  474  AGKRETHTMPQWAGSCWYYLRFCDAHNSAAPWAKEKEQYWMPVDLYIGGAEHAVLHLLYA  533
             G+RET+TMPQWAGS WYYLR+ D+HN+      E  + W+PVD+Y+GGAEHAVLHLLYA
Sbjct  484  -GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  534  RFWHQVFYEAGIVSTPEPFKKLVNQGLVLATSYRIPGKGYIYPETAKEENGK-WVAPSGE  592
            RFWH+V+Y+ G+V+T EPF+KL NQG++L+TSYR +  + +  +     +G      +GE
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  593  ELDVRQEKMSKSKLNGVDPQILIDEFGADAVRMYAMFSGPLDKNKLWSNQGVAGCRRFLN  652
            EL+    KMSKS  N V+P+ +++++GAD++R+Y MF GPLD +  WS++G+ G R+FL+
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  653  RFYEMVSSDRVKEDNNFEGLSLAHKLVQRVTDAIEKLSLNTIPSSFMEFINDFVK----L  708
            R Y ++++  + E+N+     + +  V+ VT+ ++++ +NT  + +M F+N   K    +
Sbjct  663  RVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLF  722

Query  709  AVYPKSAVEMAVRALAPIAPHISEELW-VLLGNSPGVQKSGWPSVLPEYLEEQTVTIVVQ  767
            + Y+K+ V++    +AP+APH++EELW  L +++ ++    WPS     L E+ V IVVQ
Sbjct  723  SDYAKGFVQL----IAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQ  778

Query  768  VNGKLRARLDIMKDASKEEV--LALARESASKYLEGCEVKKAIFVPARLVNFVV  819
            ++GK++A+L + KD S+EE+  +ALA E     + G ++ K I VP +LVN+V+
Sbjct  779  IKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

587) L1440_00214 in NC_020937


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  683 bits (2582),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 414/834 (50%), Positives = 598/834 (72%), Gaps = 22/834 (2%)

Query  3    YDPGLIEEKWQKFWKNEQVFKAEEDETKTKYYVLDMFPYPSGAGLHVGHLIGYTATDIVA  62
            YD   IE KWQ FW +++ FK+  D +K K+Y LDMFPYPSGAGLHVGH  GYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RCKRAQGFSVLHPMGWDSFGLPAEQYAIRTGTHPRETTEKNIANFKKQLTAMGFSYDESR  122
            R KRAQG +VLHPMGWD+FGLPAEQYA+ TG +P E T  NIANFK+Q+ A+GFSYD  R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EFATSDPEYYKWTQKLFLILYEKGLAYMADMAVNYCPELGTVLSNEEI-ENGFSVDGGYP  181
            E  T+DP+YYKWTQ +F  LYEKGLAY A+++VN   ELGT ++NEE+  +G S  GGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRMLRQWVLRITAFADQLLEGLDELDWPESVKQLQKNWIGKSSGASVNFATEHGAIE-  240
            V R+ +RQW+L+ITA+A++LLE+L+E+DWPES+K++Q+NWIGKS+GA+V F   +   + 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  -VFTTRPDTLIGVSFLALAPEHPLVDLLTSDEQKAVVAQYIKETQSKSERDRISEMKTKS  299
             VFTTRPDTL+G ++  LAPEH+LVD +T+ +Q   VA+Y +++  KS+  R    K K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  300  GVFTGSYAKHPVTHELIPIWIADYVLMGFGSGAVMGVPAHDERDLLFAEQFNLPVVSVLN  359
            GV TGSYA +PV    +P+WIADYVL ++G+GA+M+VPAHDERD  FA QFNL +++VL+
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  360  EEGVCINSCCE-GFH-----LDGLSGEEAKQYVINFLEENHLGAAKIAYKLRDWLFSRQR  413
               V   +  E G+H     LDGL    A   +++ LE + +G  +++Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  414  YWGEPIPIIHFEDGSCrplrddelpllppeIQDYRPEGVGQGPLAKVREWVQVFDTETQR  473
            YWGEPIPIIH EDG+  ++ + ELPL+ P  +D RP G G++PLA+V +W++V   +  +
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  474  AGKRETHTMPQWAGSCWYYLRFCDAHNSAAPWAKEKEQYWMPVDLYIGGAEHAVLHLLYA  533
             G+RET+TMPQWAGS WYYLR+ D+HN+      E  + W+PVD+Y+GGAEHAVLHLLYA
Sbjct  484  -GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  534  RFWHQVFYEAGIVSTPEPFKKLVNQGLVLATSYRIPGKGYIYPETAKEENGK-WVAPSGE  592
            RFWH+V+Y+ G+V+T EPF+KL NQG++L+TSYR +  + +  +     +G      +GE
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  593  ELDVRQEKMSKSKLNGVDPQILIDEFGADAVRMYAMFSGPLDKNKLWSNQGVAGCRRFLN  652
            EL+    KMSKS  N V+P+ +++++GAD++R+Y MF GPLD +  WS++G+ G R+FL+
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  653  RFYEMVSSDRVKEDNNFEGLSLAHKLVQRVTDAIEKLSLNTIPSSFMEFINDFVK----L  708
            R Y ++++  + E+N+     + +  V+ VT+ ++++ +NT  + +M F+N   K    +
Sbjct  663  RVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLF  722

Query  709  AVYPKSAVEMAVRALAPIAPHISEELW-VLLGNSPGVQKSGWPSVLPEYLEEQTVTIVVQ  767
            + Y+K+ V++    +AP+APH++EELW  L +++ ++    WPS     L E+ V IVVQ
Sbjct  723  SDYAKGFVQL----IAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQ  778

Query  768  VNGKLRARLDIMKDASKEEV--LALARESASKYLEGCEVKKAIFVPARLVNFVV  819
            ++GK++A+L + KD S+EE+  +ALA E     + G ++ K I VP +LVN+V+
Sbjct  779  IKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

588) L225667R_00213 in NC_020930


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  683 bits (2582),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 414/834 (50%), Positives = 598/834 (72%), Gaps = 22/834 (2%)

Query  3    YDPGLIEEKWQKFWKNEQVFKAEEDETKTKYYVLDMFPYPSGAGLHVGHLIGYTATDIVA  62
            YD   IE KWQ FW +++ FK+  D +K K+Y LDMFPYPSGAGLHVGH  GYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RCKRAQGFSVLHPMGWDSFGLPAEQYAIRTGTHPRETTEKNIANFKKQLTAMGFSYDESR  122
            R KRAQG +VLHPMGWD+FGLPAEQYA+ TG +P E T  NIANFK+Q+ A+GFSYD  R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EFATSDPEYYKWTQKLFLILYEKGLAYMADMAVNYCPELGTVLSNEEI-ENGFSVDGGYP  181
            E  T+DP+YYKWTQ +F  LYEKGLAY A+++VN   ELGT ++NEE+  +G S  GGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRMLRQWVLRITAFADQLLEGLDELDWPESVKQLQKNWIGKSSGASVNFATEHGAIE-  240
            V R+ +RQW+L+ITA+A++LLE+L+E+DWPES+K++Q+NWIGKS+GA+V F   +   + 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  -VFTTRPDTLIGVSFLALAPEHPLVDLLTSDEQKAVVAQYIKETQSKSERDRISEMKTKS  299
             VFTTRPDTL+G ++  LAPEH+LVD +T+ +Q   VA+Y +++  KS+  R    K K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  300  GVFTGSYAKHPVTHELIPIWIADYVLMGFGSGAVMGVPAHDERDLLFAEQFNLPVVSVLN  359
            GV TGSYA +PV    +P+WIADYVL ++G+GA+M+VPAHDERD  FA QFNL +++VL+
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  360  EEGVCINSCCE-GFH-----LDGLSGEEAKQYVINFLEENHLGAAKIAYKLRDWLFSRQR  413
               V   +  E G+H     LDGL    A   +++ LE + +G  +++Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  414  YWGEPIPIIHFEDGSCrplrddelpllppeIQDYRPEGVGQGPLAKVREWVQVFDTETQR  473
            YWGEPIPIIH EDG+  ++ + ELPL+ P  +D RP G G++PLA+V +W++V   +  +
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  474  AGKRETHTMPQWAGSCWYYLRFCDAHNSAAPWAKEKEQYWMPVDLYIGGAEHAVLHLLYA  533
             G+RET+TMPQWAGS WYYLR+ D+HN+      E  + W+PVD+Y+GGAEHAVLHLLYA
Sbjct  484  -GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  534  RFWHQVFYEAGIVSTPEPFKKLVNQGLVLATSYRIPGKGYIYPETAKEENGK-WVAPSGE  592
            RFWH+V+Y+ G+V+T EPF+KL NQG++L+TSYR +  + +  +     +G      +GE
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  593  ELDVRQEKMSKSKLNGVDPQILIDEFGADAVRMYAMFSGPLDKNKLWSNQGVAGCRRFLN  652
            EL+    KMSKS  N V+P+ +++++GAD++R+Y MF GPLD +  WS++G+ G R+FL+
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  653  RFYEMVSSDRVKEDNNFEGLSLAHKLVQRVTDAIEKLSLNTIPSSFMEFINDFVK----L  708
            R Y ++++  + E+N+     + +  V+ VT+ ++++ +NT  + +M F+N   K    +
Sbjct  663  RVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLF  722

Query  709  AVYPKSAVEMAVRALAPIAPHISEELW-VLLGNSPGVQKSGWPSVLPEYLEEQTVTIVVQ  767
            + Y+K+ V++    +AP+APH++EELW  L +++ ++    WPS     L E+ V IVVQ
Sbjct  723  SDYAKGFVQL----IAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQ  778

Query  768  VNGKLRARLDIMKDASKEEV--LALARESASKYLEGCEVKKAIFVPARLVNFVV  819
            ++GK++A+L + KD S+EE+  +ALA E     + G ++ K I VP +LVN+V+
Sbjct  779  IKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

589) leuS in NC_021052


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  683 bits (2582),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 414/834 (50%), Positives = 598/834 (72%), Gaps = 22/834 (2%)

Query  3    YDPGLIEEKWQKFWKNEQVFKAEEDETKTKYYVLDMFPYPSGAGLHVGHLIGYTATDIVA  62
            YD   IE KWQ FW +++ FK+  D +K K+Y LDMFPYPSGAGLHVGH  GYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RCKRAQGFSVLHPMGWDSFGLPAEQYAIRTGTHPRETTEKNIANFKKQLTAMGFSYDESR  122
            R KRAQG +VLHPMGWD+FGLPAEQYA+ TG +P E T  NIANFK+Q+ A+GFSYD  R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EFATSDPEYYKWTQKLFLILYEKGLAYMADMAVNYCPELGTVLSNEEI-ENGFSVDGGYP  181
            E  T+DP+YYKWTQ +F  LYEKGLAY A+++VN   ELGT ++NEE+  +G S  GGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRMLRQWVLRITAFADQLLEGLDELDWPESVKQLQKNWIGKSSGASVNFATEHGAIE-  240
            V R+ +RQW+L+ITA+A++LLE+L+E+DWPES+K++Q+NWIGKS+GA+V F   +   + 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  -VFTTRPDTLIGVSFLALAPEHPLVDLLTSDEQKAVVAQYIKETQSKSERDRISEMKTKS  299
             VFTTRPDTL+G ++  LAPEH+LVD +T+ +Q   VA+Y +++  KS+  R    K K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  300  GVFTGSYAKHPVTHELIPIWIADYVLMGFGSGAVMGVPAHDERDLLFAEQFNLPVVSVLN  359
            GV TGSYA +PV    +P+WIADYVL ++G+GA+M+VPAHDERD  FA QFNL +++VL+
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  360  EEGVCINSCCE-GFH-----LDGLSGEEAKQYVINFLEENHLGAAKIAYKLRDWLFSRQR  413
               V   +  E G+H     LDGL    A   +++ LE + +G  +++Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  414  YWGEPIPIIHFEDGSCrplrddelpllppeIQDYRPEGVGQGPLAKVREWVQVFDTETQR  473
            YWGEPIPIIH EDG+  ++ + ELPL+ P  +D RP G G++PLA+V +W++V   +  +
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  474  AGKRETHTMPQWAGSCWYYLRFCDAHNSAAPWAKEKEQYWMPVDLYIGGAEHAVLHLLYA  533
             G+RET+TMPQWAGS WYYLR+ D+HN+      E  + W+PVD+Y+GGAEHAVLHLLYA
Sbjct  484  -GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  534  RFWHQVFYEAGIVSTPEPFKKLVNQGLVLATSYRIPGKGYIYPETAKEENGK-WVAPSGE  592
            RFWH+V+Y+ G+V+T EPF+KL NQG++L+TSYR +  + +  +     +G      +GE
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  593  ELDVRQEKMSKSKLNGVDPQILIDEFGADAVRMYAMFSGPLDKNKLWSNQGVAGCRRFLN  652
            EL+    KMSKS  N V+P+ +++++GAD++R+Y MF GPLD +  WS++G+ G R+FL+
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  653  RFYEMVSSDRVKEDNNFEGLSLAHKLVQRVTDAIEKLSLNTIPSSFMEFINDFVK----L  708
            R Y ++++  + E+N+     + +  V+ VT+ ++++ +NT  + +M F+N   K    +
Sbjct  663  RVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLF  722

Query  709  AVYPKSAVEMAVRALAPIAPHISEELW-VLLGNSPGVQKSGWPSVLPEYLEEQTVTIVVQ  767
            + Y+K+ V++    +AP+APH++EELW  L +++ ++    WPS     L E+ V IVVQ
Sbjct  723  SDYAKGFVQL----IAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQ  778

Query  768  VNGKLRARLDIMKDASKEEV--LALARESASKYLEGCEVKKAIFVPARLVNFVV  819
            ++GK++A+L + KD S+EE+  +ALA E     + G ++ K I VP +LVN+V+
Sbjct  779  IKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

590) leuS in NC_021050


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  683 bits (2582),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 414/834 (50%), Positives = 598/834 (72%), Gaps = 22/834 (2%)

Query  3    YDPGLIEEKWQKFWKNEQVFKAEEDETKTKYYVLDMFPYPSGAGLHVGHLIGYTATDIVA  62
            YD   IE KWQ FW +++ FK+  D +K K+Y LDMFPYPSGAGLHVGH  GYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RCKRAQGFSVLHPMGWDSFGLPAEQYAIRTGTHPRETTEKNIANFKKQLTAMGFSYDESR  122
            R KRAQG +VLHPMGWD+FGLPAEQYA+ TG +P E T  NIANFK+Q+ A+GFSYD  R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EFATSDPEYYKWTQKLFLILYEKGLAYMADMAVNYCPELGTVLSNEEI-ENGFSVDGGYP  181
            E  T+DP+YYKWTQ +F  LYEKGLAY A+++VN   ELGT ++NEE+  +G S  GGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRMLRQWVLRITAFADQLLEGLDELDWPESVKQLQKNWIGKSSGASVNFATEHGAIE-  240
            V R+ +RQW+L+ITA+A++LLE+L+E+DWPES+K++Q+NWIGKS+GA+V F   +   + 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  -VFTTRPDTLIGVSFLALAPEHPLVDLLTSDEQKAVVAQYIKETQSKSERDRISEMKTKS  299
             VFTTRPDTL+G ++  LAPEH+LVD +T+ +Q   VA+Y +++  KS+  R    K K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  300  GVFTGSYAKHPVTHELIPIWIADYVLMGFGSGAVMGVPAHDERDLLFAEQFNLPVVSVLN  359
            GV TGSYA +PV    +P+WIADYVL ++G+GA+M+VPAHDERD  FA QFNL +++VL+
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  360  EEGVCINSCCE-GFH-----LDGLSGEEAKQYVINFLEENHLGAAKIAYKLRDWLFSRQR  413
               V   +  E G+H     LDGL    A   +++ LE + +G  +++Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  414  YWGEPIPIIHFEDGSCrplrddelpllppeIQDYRPEGVGQGPLAKVREWVQVFDTETQR  473
            YWGEPIPIIH EDG+  ++ + ELPL+ P  +D RP G G++PLA+V +W++V   +  +
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  474  AGKRETHTMPQWAGSCWYYLRFCDAHNSAAPWAKEKEQYWMPVDLYIGGAEHAVLHLLYA  533
             G+RET+TMPQWAGS WYYLR+ D+HN+      E  + W+PVD+Y+GGAEHAVLHLLYA
Sbjct  484  -GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  534  RFWHQVFYEAGIVSTPEPFKKLVNQGLVLATSYRIPGKGYIYPETAKEENGK-WVAPSGE  592
            RFWH+V+Y+ G+V+T EPF+KL NQG++L+TSYR +  + +  +     +G      +GE
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  593  ELDVRQEKMSKSKLNGVDPQILIDEFGADAVRMYAMFSGPLDKNKLWSNQGVAGCRRFLN  652
            EL+    KMSKS  N V+P+ +++++GAD++R+Y MF GPLD +  WS++G+ G R+FL+
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  653  RFYEMVSSDRVKEDNNFEGLSLAHKLVQRVTDAIEKLSLNTIPSSFMEFINDFVK----L  708
            R Y ++++  + E+N+     + +  V+ VT+ ++++ +NT  + +M F+N   K    +
Sbjct  663  RVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLF  722

Query  709  AVYPKSAVEMAVRALAPIAPHISEELW-VLLGNSPGVQKSGWPSVLPEYLEEQTVTIVVQ  767
            + Y+K+ V++    +AP+APH++EELW  L +++ ++    WPS     L E+ V IVVQ
Sbjct  723  SDYAKGFVQL----IAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQ  778

Query  768  VNGKLRARLDIMKDASKEEV--LALARESASKYLEGCEVKKAIFVPARLVNFVV  819
            ++GK++A+L + KD S+EE+  +ALA E     + G ++ K I VP +LVN+V+
Sbjct  779  IKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

591) L2B795_00213 in NC_020938


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  683 bits (2582),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 414/834 (50%), Positives = 598/834 (72%), Gaps = 22/834 (2%)

Query  3    YDPGLIEEKWQKFWKNEQVFKAEEDETKTKYYVLDMFPYPSGAGLHVGHLIGYTATDIVA  62
            YD   IE KWQ FW +++ FK+  D +K K+Y LDMFPYPSGAGLHVGH  GYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RCKRAQGFSVLHPMGWDSFGLPAEQYAIRTGTHPRETTEKNIANFKKQLTAMGFSYDESR  122
            R KRAQG +VLHPMGWD+FGLPAEQYA+ TG +P E T  NIANFK+Q+ A+GFSYD  R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EFATSDPEYYKWTQKLFLILYEKGLAYMADMAVNYCPELGTVLSNEEI-ENGFSVDGGYP  181
            E  T+DP+YYKWTQ +F  LYEKGLAY A+++VN   ELGT ++NEE+  +G S  GGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRMLRQWVLRITAFADQLLEGLDELDWPESVKQLQKNWIGKSSGASVNFATEHGAIE-  240
            V R+ +RQW+L+ITA+A++LLE+L+E+DWPES+K++Q+NWIGKS+GA+V F   +   + 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  -VFTTRPDTLIGVSFLALAPEHPLVDLLTSDEQKAVVAQYIKETQSKSERDRISEMKTKS  299
             VFTTRPDTL+G ++  LAPEH+LVD +T+ +Q   VA+Y +++  KS+  R    K K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  300  GVFTGSYAKHPVTHELIPIWIADYVLMGFGSGAVMGVPAHDERDLLFAEQFNLPVVSVLN  359
            GV TGSYA +PV    +P+WIADYVL ++G+GA+M+VPAHDERD  FA QFNL +++VL+
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  360  EEGVCINSCCE-GFH-----LDGLSGEEAKQYVINFLEENHLGAAKIAYKLRDWLFSRQR  413
               V   +  E G+H     LDGL    A   +++ LE + +G  +++Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  414  YWGEPIPIIHFEDGSCrplrddelpllppeIQDYRPEGVGQGPLAKVREWVQVFDTETQR  473
            YWGEPIPIIH EDG+  ++ + ELPL+ P  +D RP G G++PLA+V +W++V   +  +
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  474  AGKRETHTMPQWAGSCWYYLRFCDAHNSAAPWAKEKEQYWMPVDLYIGGAEHAVLHLLYA  533
             G+RET+TMPQWAGS WYYLR+ D+HN+      E  + W+PVD+Y+GGAEHAVLHLLYA
Sbjct  484  -GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  534  RFWHQVFYEAGIVSTPEPFKKLVNQGLVLATSYRIPGKGYIYPETAKEENGK-WVAPSGE  592
            RFWH+V+Y+ G+V+T EPF+KL NQG++L+TSYR +  + +  +     +G      +GE
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  593  ELDVRQEKMSKSKLNGVDPQILIDEFGADAVRMYAMFSGPLDKNKLWSNQGVAGCRRFLN  652
            EL+    KMSKS  N V+P+ +++++GAD++R+Y MF GPLD +  WS++G+ G R+FL+
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  653  RFYEMVSSDRVKEDNNFEGLSLAHKLVQRVTDAIEKLSLNTIPSSFMEFINDFVK----L  708
            R Y ++++  + E+N+     + +  V+ VT+ ++++ +NT  + +M F+N   K    +
Sbjct  663  RVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLF  722

Query  709  AVYPKSAVEMAVRALAPIAPHISEELW-VLLGNSPGVQKSGWPSVLPEYLEEQTVTIVVQ  767
            + Y+K+ V++    +AP+APH++EELW  L +++ ++    WPS     L E+ V IVVQ
Sbjct  723  SDYAKGFVQL----IAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQ  778

Query  768  VNGKLRARLDIMKDASKEEV--LALARESASKYLEGCEVKKAIFVPARLVNFVV  819
            ++GK++A+L + KD S+EE+  +ALA E     + G ++ K I VP +LVN+V+
Sbjct  779  IKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

592) L2B8200_00212 in NC_020945


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  683 bits (2582),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 414/834 (50%), Positives = 598/834 (72%), Gaps = 22/834 (2%)

Query  3    YDPGLIEEKWQKFWKNEQVFKAEEDETKTKYYVLDMFPYPSGAGLHVGHLIGYTATDIVA  62
            YD   IE KWQ FW +++ FK+  D +K K+Y LDMFPYPSGAGLHVGH  GYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RCKRAQGFSVLHPMGWDSFGLPAEQYAIRTGTHPRETTEKNIANFKKQLTAMGFSYDESR  122
            R KRAQG +VLHPMGWD+FGLPAEQYA+ TG +P E T  NIANFK+Q+ A+GFSYD  R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EFATSDPEYYKWTQKLFLILYEKGLAYMADMAVNYCPELGTVLSNEEI-ENGFSVDGGYP  181
            E  T+DP+YYKWTQ +F  LYEKGLAY A+++VN   ELGT ++NEE+  +G S  GGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRMLRQWVLRITAFADQLLEGLDELDWPESVKQLQKNWIGKSSGASVNFATEHGAIE-  240
            V R+ +RQW+L+ITA+A++LLE+L+E+DWPES+K++Q+NWIGKS+GA+V F   +   + 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  -VFTTRPDTLIGVSFLALAPEHPLVDLLTSDEQKAVVAQYIKETQSKSERDRISEMKTKS  299
             VFTTRPDTL+G ++  LAPEH+LVD +T+ +Q   VA+Y +++  KS+  R    K K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  300  GVFTGSYAKHPVTHELIPIWIADYVLMGFGSGAVMGVPAHDERDLLFAEQFNLPVVSVLN  359
            GV TGSYA +PV    +P+WIADYVL ++G+GA+M+VPAHDERD  FA QFNL +++VL+
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  360  EEGVCINSCCE-GFH-----LDGLSGEEAKQYVINFLEENHLGAAKIAYKLRDWLFSRQR  413
               V   +  E G+H     LDGL    A   +++ LE + +G  +++Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  414  YWGEPIPIIHFEDGSCrplrddelpllppeIQDYRPEGVGQGPLAKVREWVQVFDTETQR  473
            YWGEPIPIIH EDG+  ++ + ELPL+ P  +D RP G G++PLA+V +W++V   +  +
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  474  AGKRETHTMPQWAGSCWYYLRFCDAHNSAAPWAKEKEQYWMPVDLYIGGAEHAVLHLLYA  533
             G+RET+TMPQWAGS WYYLR+ D+HN+      E  + W+PVD+Y+GGAEHAVLHLLYA
Sbjct  484  -GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  534  RFWHQVFYEAGIVSTPEPFKKLVNQGLVLATSYRIPGKGYIYPETAKEENGK-WVAPSGE  592
            RFWH+V+Y+ G+V+T EPF+KL NQG++L+TSYR +  + +  +     +G      +GE
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  593  ELDVRQEKMSKSKLNGVDPQILIDEFGADAVRMYAMFSGPLDKNKLWSNQGVAGCRRFLN  652
            EL+    KMSKS  N V+P+ +++++GAD++R+Y MF GPLD +  WS++G+ G R+FL+
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  653  RFYEMVSSDRVKEDNNFEGLSLAHKLVQRVTDAIEKLSLNTIPSSFMEFINDFVK----L  708
            R Y ++++  + E+N+     + +  V+ VT+ ++++ +NT  + +M F+N   K    +
Sbjct  663  RVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLF  722

Query  709  AVYPKSAVEMAVRALAPIAPHISEELW-VLLGNSPGVQKSGWPSVLPEYLEEQTVTIVVQ  767
            + Y+K+ V++    +AP+APH++EELW  L +++ ++    WPS     L E+ V IVVQ
Sbjct  723  SDYAKGFVQL----IAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQ  778

Query  768  VNGKLRARLDIMKDASKEEV--LALARESASKYLEGCEVKKAIFVPARLVNFVV  819
            ++GK++A+L + KD S+EE+  +ALA E     + G ++ K I VP +LVN+V+
Sbjct  779  IKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

593) L2BAMS1_00212 in NC_020933


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  683 bits (2582),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 414/834 (50%), Positives = 598/834 (72%), Gaps = 22/834 (2%)

Query  3    YDPGLIEEKWQKFWKNEQVFKAEEDETKTKYYVLDMFPYPSGAGLHVGHLIGYTATDIVA  62
            YD   IE KWQ FW +++ FK+  D +K K+Y LDMFPYPSGAGLHVGH  GYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RCKRAQGFSVLHPMGWDSFGLPAEQYAIRTGTHPRETTEKNIANFKKQLTAMGFSYDESR  122
            R KRAQG +VLHPMGWD+FGLPAEQYA+ TG +P E T  NIANFK+Q+ A+GFSYD  R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EFATSDPEYYKWTQKLFLILYEKGLAYMADMAVNYCPELGTVLSNEEI-ENGFSVDGGYP  181
            E  T+DP+YYKWTQ +F  LYEKGLAY A+++VN   ELGT ++NEE+  +G S  GGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRMLRQWVLRITAFADQLLEGLDELDWPESVKQLQKNWIGKSSGASVNFATEHGAIE-  240
            V R+ +RQW+L+ITA+A++LLE+L+E+DWPES+K++Q+NWIGKS+GA+V F   +   + 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  -VFTTRPDTLIGVSFLALAPEHPLVDLLTSDEQKAVVAQYIKETQSKSERDRISEMKTKS  299
             VFTTRPDTL+G ++  LAPEH+LVD +T+ +Q   VA+Y +++  KS+  R    K K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  300  GVFTGSYAKHPVTHELIPIWIADYVLMGFGSGAVMGVPAHDERDLLFAEQFNLPVVSVLN  359
            GV TGSYA +PV    +P+WIADYVL ++G+GA+M+VPAHDERD  FA QFNL +++VL+
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  360  EEGVCINSCCE-GFH-----LDGLSGEEAKQYVINFLEENHLGAAKIAYKLRDWLFSRQR  413
               V   +  E G+H     LDGL    A   +++ LE + +G  +++Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  414  YWGEPIPIIHFEDGSCrplrddelpllppeIQDYRPEGVGQGPLAKVREWVQVFDTETQR  473
            YWGEPIPIIH EDG+  ++ + ELPL+ P  +D RP G G++PLA+V +W++V   +  +
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  474  AGKRETHTMPQWAGSCWYYLRFCDAHNSAAPWAKEKEQYWMPVDLYIGGAEHAVLHLLYA  533
             G+RET+TMPQWAGS WYYLR+ D+HN+      E  + W+PVD+Y+GGAEHAVLHLLYA
Sbjct  484  -GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  534  RFWHQVFYEAGIVSTPEPFKKLVNQGLVLATSYRIPGKGYIYPETAKEENGK-WVAPSGE  592
            RFWH+V+Y+ G+V+T EPF+KL NQG++L+TSYR +  + +  +     +G      +GE
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  593  ELDVRQEKMSKSKLNGVDPQILIDEFGADAVRMYAMFSGPLDKNKLWSNQGVAGCRRFLN  652
            EL+    KMSKS  N V+P+ +++++GAD++R+Y MF GPLD +  WS++G+ G R+FL+
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  653  RFYEMVSSDRVKEDNNFEGLSLAHKLVQRVTDAIEKLSLNTIPSSFMEFINDFVK----L  708
            R Y ++++  + E+N+     + +  V+ VT+ ++++ +NT  + +M F+N   K    +
Sbjct  663  RVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLF  722

Query  709  AVYPKSAVEMAVRALAPIAPHISEELW-VLLGNSPGVQKSGWPSVLPEYLEEQTVTIVVQ  767
            + Y+K+ V++    +AP+APH++EELW  L +++ ++    WPS     L E+ V IVVQ
Sbjct  723  SDYAKGFVQL----IAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQ  778

Query  768  VNGKLRARLDIMKDASKEEV--LALARESASKYLEGCEVKKAIFVPARLVNFVV  819
            ++GK++A+L + KD S+EE+  +ALA E     + G ++ K I VP +LVN+V+
Sbjct  779  IKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

594) L2BAMS2_00212 in NC_020934


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  683 bits (2582),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 414/834 (50%), Positives = 598/834 (72%), Gaps = 22/834 (2%)

Query  3    YDPGLIEEKWQKFWKNEQVFKAEEDETKTKYYVLDMFPYPSGAGLHVGHLIGYTATDIVA  62
            YD   IE KWQ FW +++ FK+  D +K K+Y LDMFPYPSGAGLHVGH  GYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RCKRAQGFSVLHPMGWDSFGLPAEQYAIRTGTHPRETTEKNIANFKKQLTAMGFSYDESR  122
            R KRAQG +VLHPMGWD+FGLPAEQYA+ TG +P E T  NIANFK+Q+ A+GFSYD  R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EFATSDPEYYKWTQKLFLILYEKGLAYMADMAVNYCPELGTVLSNEEI-ENGFSVDGGYP  181
            E  T+DP+YYKWTQ +F  LYEKGLAY A+++VN   ELGT ++NEE+  +G S  GGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRMLRQWVLRITAFADQLLEGLDELDWPESVKQLQKNWIGKSSGASVNFATEHGAIE-  240
            V R+ +RQW+L+ITA+A++LLE+L+E+DWPES+K++Q+NWIGKS+GA+V F   +   + 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  -VFTTRPDTLIGVSFLALAPEHPLVDLLTSDEQKAVVAQYIKETQSKSERDRISEMKTKS  299
             VFTTRPDTL+G ++  LAPEH+LVD +T+ +Q   VA+Y +++  KS+  R    K K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  300  GVFTGSYAKHPVTHELIPIWIADYVLMGFGSGAVMGVPAHDERDLLFAEQFNLPVVSVLN  359
            GV TGSYA +PV    +P+WIADYVL ++G+GA+M+VPAHDERD  FA QFNL +++VL+
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  360  EEGVCINSCCE-GFH-----LDGLSGEEAKQYVINFLEENHLGAAKIAYKLRDWLFSRQR  413
               V   +  E G+H     LDGL    A   +++ LE + +G  +++Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  414  YWGEPIPIIHFEDGSCrplrddelpllppeIQDYRPEGVGQGPLAKVREWVQVFDTETQR  473
            YWGEPIPIIH EDG+  ++ + ELPL+ P  +D RP G G++PLA+V +W++V   +  +
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  474  AGKRETHTMPQWAGSCWYYLRFCDAHNSAAPWAKEKEQYWMPVDLYIGGAEHAVLHLLYA  533
             G+RET+TMPQWAGS WYYLR+ D+HN+      E  + W+PVD+Y+GGAEHAVLHLLYA
Sbjct  484  -GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  534  RFWHQVFYEAGIVSTPEPFKKLVNQGLVLATSYRIPGKGYIYPETAKEENGK-WVAPSGE  592
            RFWH+V+Y+ G+V+T EPF+KL NQG++L+TSYR +  + +  +     +G      +GE
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  593  ELDVRQEKMSKSKLNGVDPQILIDEFGADAVRMYAMFSGPLDKNKLWSNQGVAGCRRFLN  652
            EL+    KMSKS  N V+P+ +++++GAD++R+Y MF GPLD +  WS++G+ G R+FL+
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  653  RFYEMVSSDRVKEDNNFEGLSLAHKLVQRVTDAIEKLSLNTIPSSFMEFINDFVK----L  708
            R Y ++++  + E+N+     + +  V+ VT+ ++++ +NT  + +M F+N   K    +
Sbjct  663  RVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLF  722

Query  709  AVYPKSAVEMAVRALAPIAPHISEELW-VLLGNSPGVQKSGWPSVLPEYLEEQTVTIVVQ  767
            + Y+K+ V++    +AP+APH++EELW  L +++ ++    WPS     L E+ V IVVQ
Sbjct  723  SDYAKGFVQL----IAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQ  778

Query  768  VNGKLRARLDIMKDASKEEV--LALARESASKYLEGCEVKKAIFVPARLVNFVV  819
            ++GK++A+L + KD S+EE+  +ALA E     + G ++ K I VP +LVN+V+
Sbjct  779  IKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

595) L2BAMS3_00212 in NC_020977


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  683 bits (2582),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 414/834 (50%), Positives = 598/834 (72%), Gaps = 22/834 (2%)

Query  3    YDPGLIEEKWQKFWKNEQVFKAEEDETKTKYYVLDMFPYPSGAGLHVGHLIGYTATDIVA  62
            YD   IE KWQ FW +++ FK+  D +K K+Y LDMFPYPSGAGLHVGH  GYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RCKRAQGFSVLHPMGWDSFGLPAEQYAIRTGTHPRETTEKNIANFKKQLTAMGFSYDESR  122
            R KRAQG +VLHPMGWD+FGLPAEQYA+ TG +P E T  NIANFK+Q+ A+GFSYD  R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EFATSDPEYYKWTQKLFLILYEKGLAYMADMAVNYCPELGTVLSNEEI-ENGFSVDGGYP  181
            E  T+DP+YYKWTQ +F  LYEKGLAY A+++VN   ELGT ++NEE+  +G S  GGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRMLRQWVLRITAFADQLLEGLDELDWPESVKQLQKNWIGKSSGASVNFATEHGAIE-  240
            V R+ +RQW+L+ITA+A++LLE+L+E+DWPES+K++Q+NWIGKS+GA+V F   +   + 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  -VFTTRPDTLIGVSFLALAPEHPLVDLLTSDEQKAVVAQYIKETQSKSERDRISEMKTKS  299
             VFTTRPDTL+G ++  LAPEH+LVD +T+ +Q   VA+Y +++  KS+  R    K K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  300  GVFTGSYAKHPVTHELIPIWIADYVLMGFGSGAVMGVPAHDERDLLFAEQFNLPVVSVLN  359
            GV TGSYA +PV    +P+WIADYVL ++G+GA+M+VPAHDERD  FA QFNL +++VL+
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  360  EEGVCINSCCE-GFH-----LDGLSGEEAKQYVINFLEENHLGAAKIAYKLRDWLFSRQR  413
               V   +  E G+H     LDGL    A   +++ LE + +G  +++Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  414  YWGEPIPIIHFEDGSCrplrddelpllppeIQDYRPEGVGQGPLAKVREWVQVFDTETQR  473
            YWGEPIPIIH EDG+  ++ + ELPL+ P  +D RP G G++PLA+V +W++V   +  +
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  474  AGKRETHTMPQWAGSCWYYLRFCDAHNSAAPWAKEKEQYWMPVDLYIGGAEHAVLHLLYA  533
             G+RET+TMPQWAGS WYYLR+ D+HN+      E  + W+PVD+Y+GGAEHAVLHLLYA
Sbjct  484  -GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  534  RFWHQVFYEAGIVSTPEPFKKLVNQGLVLATSYRIPGKGYIYPETAKEENGK-WVAPSGE  592
            RFWH+V+Y+ G+V+T EPF+KL NQG++L+TSYR +  + +  +     +G      +GE
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  593  ELDVRQEKMSKSKLNGVDPQILIDEFGADAVRMYAMFSGPLDKNKLWSNQGVAGCRRFLN  652
            EL+    KMSKS  N V+P+ +++++GAD++R+Y MF GPLD +  WS++G+ G R+FL+
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  653  RFYEMVSSDRVKEDNNFEGLSLAHKLVQRVTDAIEKLSLNTIPSSFMEFINDFVK----L  708
            R Y ++++  + E+N+     + +  V+ VT+ ++++ +NT  + +M F+N   K    +
Sbjct  663  RVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLF  722

Query  709  AVYPKSAVEMAVRALAPIAPHISEELW-VLLGNSPGVQKSGWPSVLPEYLEEQTVTIVVQ  767
            + Y+K+ V++    +AP+APH++EELW  L +++ ++    WPS     L E+ V IVVQ
Sbjct  723  SDYAKGFVQL----IAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQ  778

Query  768  VNGKLRARLDIMKDASKEEV--LALARESASKYLEGCEVKKAIFVPARLVNFVV  819
            ++GK++A+L + KD S+EE+  +ALA E     + G ++ K I VP +LVN+V+
Sbjct  779  IKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

596) L2BAMS4_00213 in NC_020978


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  683 bits (2582),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 414/834 (50%), Positives = 598/834 (72%), Gaps = 22/834 (2%)

Query  3    YDPGLIEEKWQKFWKNEQVFKAEEDETKTKYYVLDMFPYPSGAGLHVGHLIGYTATDIVA  62
            YD   IE KWQ FW +++ FK+  D +K K+Y LDMFPYPSGAGLHVGH  GYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RCKRAQGFSVLHPMGWDSFGLPAEQYAIRTGTHPRETTEKNIANFKKQLTAMGFSYDESR  122
            R KRAQG +VLHPMGWD+FGLPAEQYA+ TG +P E T  NIANFK+Q+ A+GFSYD  R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EFATSDPEYYKWTQKLFLILYEKGLAYMADMAVNYCPELGTVLSNEEI-ENGFSVDGGYP  181
            E  T+DP+YYKWTQ +F  LYEKGLAY A+++VN   ELGT ++NEE+  +G S  GGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRMLRQWVLRITAFADQLLEGLDELDWPESVKQLQKNWIGKSSGASVNFATEHGAIE-  240
            V R+ +RQW+L+ITA+A++LLE+L+E+DWPES+K++Q+NWIGKS+GA+V F   +   + 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  -VFTTRPDTLIGVSFLALAPEHPLVDLLTSDEQKAVVAQYIKETQSKSERDRISEMKTKS  299
             VFTTRPDTL+G ++  LAPEH+LVD +T+ +Q   VA+Y +++  KS+  R    K K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  300  GVFTGSYAKHPVTHELIPIWIADYVLMGFGSGAVMGVPAHDERDLLFAEQFNLPVVSVLN  359
            GV TGSYA +PV    +P+WIADYVL ++G+GA+M+VPAHDERD  FA QFNL +++VL+
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  360  EEGVCINSCCE-GFH-----LDGLSGEEAKQYVINFLEENHLGAAKIAYKLRDWLFSRQR  413
               V   +  E G+H     LDGL    A   +++ LE + +G  +++Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  414  YWGEPIPIIHFEDGSCrplrddelpllppeIQDYRPEGVGQGPLAKVREWVQVFDTETQR  473
            YWGEPIPIIH EDG+  ++ + ELPL+ P  +D RP G G++PLA+V +W++V   +  +
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  474  AGKRETHTMPQWAGSCWYYLRFCDAHNSAAPWAKEKEQYWMPVDLYIGGAEHAVLHLLYA  533
             G+RET+TMPQWAGS WYYLR+ D+HN+      E  + W+PVD+Y+GGAEHAVLHLLYA
Sbjct  484  -GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  534  RFWHQVFYEAGIVSTPEPFKKLVNQGLVLATSYRIPGKGYIYPETAKEENGK-WVAPSGE  592
            RFWH+V+Y+ G+V+T EPF+KL NQG++L+TSYR +  + +  +     +G      +GE
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  593  ELDVRQEKMSKSKLNGVDPQILIDEFGADAVRMYAMFSGPLDKNKLWSNQGVAGCRRFLN  652
            EL+    KMSKS  N V+P+ +++++GAD++R+Y MF GPLD +  WS++G+ G R+FL+
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  653  RFYEMVSSDRVKEDNNFEGLSLAHKLVQRVTDAIEKLSLNTIPSSFMEFINDFVK----L  708
            R Y ++++  + E+N+     + +  V+ VT+ ++++ +NT  + +M F+N   K    +
Sbjct  663  RVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLF  722

Query  709  AVYPKSAVEMAVRALAPIAPHISEELW-VLLGNSPGVQKSGWPSVLPEYLEEQTVTIVVQ  767
            + Y+K+ V++    +AP+APH++EELW  L +++ ++    WPS     L E+ V IVVQ
Sbjct  723  SDYAKGFVQL----IAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQ  778

Query  768  VNGKLRARLDIMKDASKEEV--LALARESASKYLEGCEVKKAIFVPARLVNFVV  819
            ++GK++A+L + KD S+EE+  +ALA E     + G ++ K I VP +LVN+V+
Sbjct  779  IKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

597) L2BAMS5_00213 in NC_020936


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  683 bits (2582),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 414/834 (50%), Positives = 598/834 (72%), Gaps = 22/834 (2%)

Query  3    YDPGLIEEKWQKFWKNEQVFKAEEDETKTKYYVLDMFPYPSGAGLHVGHLIGYTATDIVA  62
            YD   IE KWQ FW +++ FK+  D +K K+Y LDMFPYPSGAGLHVGH  GYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RCKRAQGFSVLHPMGWDSFGLPAEQYAIRTGTHPRETTEKNIANFKKQLTAMGFSYDESR  122
            R KRAQG +VLHPMGWD+FGLPAEQYA+ TG +P E T  NIANFK+Q+ A+GFSYD  R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EFATSDPEYYKWTQKLFLILYEKGLAYMADMAVNYCPELGTVLSNEEI-ENGFSVDGGYP  181
            E  T+DP+YYKWTQ +F  LYEKGLAY A+++VN   ELGT ++NEE+  +G S  GGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRMLRQWVLRITAFADQLLEGLDELDWPESVKQLQKNWIGKSSGASVNFATEHGAIE-  240
            V R+ +RQW+L+ITA+A++LLE+L+E+DWPES+K++Q+NWIGKS+GA+V F   +   + 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  -VFTTRPDTLIGVSFLALAPEHPLVDLLTSDEQKAVVAQYIKETQSKSERDRISEMKTKS  299
             VFTTRPDTL+G ++  LAPEH+LVD +T+ +Q   VA+Y +++  KS+  R    K K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  300  GVFTGSYAKHPVTHELIPIWIADYVLMGFGSGAVMGVPAHDERDLLFAEQFNLPVVSVLN  359
            GV TGSYA +PV    +P+WIADYVL ++G+GA+M+VPAHDERD  FA QFNL +++VL+
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  360  EEGVCINSCCE-GFH-----LDGLSGEEAKQYVINFLEENHLGAAKIAYKLRDWLFSRQR  413
               V   +  E G+H     LDGL    A   +++ LE + +G  +++Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  414  YWGEPIPIIHFEDGSCrplrddelpllppeIQDYRPEGVGQGPLAKVREWVQVFDTETQR  473
            YWGEPIPIIH EDG+  ++ + ELPL+ P  +D RP G G++PLA+V +W++V   +  +
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  474  AGKRETHTMPQWAGSCWYYLRFCDAHNSAAPWAKEKEQYWMPVDLYIGGAEHAVLHLLYA  533
             G+RET+TMPQWAGS WYYLR+ D+HN+      E  + W+PVD+Y+GGAEHAVLHLLYA
Sbjct  484  -GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  534  RFWHQVFYEAGIVSTPEPFKKLVNQGLVLATSYRIPGKGYIYPETAKEENGK-WVAPSGE  592
            RFWH+V+Y+ G+V+T EPF+KL NQG++L+TSYR +  + +  +     +G      +GE
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  593  ELDVRQEKMSKSKLNGVDPQILIDEFGADAVRMYAMFSGPLDKNKLWSNQGVAGCRRFLN  652
            EL+    KMSKS  N V+P+ +++++GAD++R+Y MF GPLD +  WS++G+ G R+FL+
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  653  RFYEMVSSDRVKEDNNFEGLSLAHKLVQRVTDAIEKLSLNTIPSSFMEFINDFVK----L  708
            R Y ++++  + E+N+     + +  V+ VT+ ++++ +NT  + +M F+N   K    +
Sbjct  663  RVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLF  722

Query  709  AVYPKSAVEMAVRALAPIAPHISEELW-VLLGNSPGVQKSGWPSVLPEYLEEQTVTIVVQ  767
            + Y+K+ V++    +AP+APH++EELW  L +++ ++    WPS     L E+ V IVVQ
Sbjct  723  SDYAKGFVQL----IAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQ  778

Query  768  VNGKLRARLDIMKDASKEEV--LALARESASKYLEGCEVKKAIFVPARLVNFVV  819
            ++GK++A+L + KD S+EE+  +ALA E     + G ++ K I VP +LVN+V+
Sbjct  779  IKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

598) L2BCAN1_00214 in NC_020935


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  683 bits (2582),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 414/834 (50%), Positives = 598/834 (72%), Gaps = 22/834 (2%)

Query  3    YDPGLIEEKWQKFWKNEQVFKAEEDETKTKYYVLDMFPYPSGAGLHVGHLIGYTATDIVA  62
            YD   IE KWQ FW +++ FK+  D +K K+Y LDMFPYPSGAGLHVGH  GYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RCKRAQGFSVLHPMGWDSFGLPAEQYAIRTGTHPRETTEKNIANFKKQLTAMGFSYDESR  122
            R KRAQG +VLHPMGWD+FGLPAEQYA+ TG +P E T  NIANFK+Q+ A+GFSYD  R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EFATSDPEYYKWTQKLFLILYEKGLAYMADMAVNYCPELGTVLSNEEI-ENGFSVDGGYP  181
            E  T+DP+YYKWTQ +F  LYEKGLAY A+++VN   ELGT ++NEE+  +G S  GGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRMLRQWVLRITAFADQLLEGLDELDWPESVKQLQKNWIGKSSGASVNFATEHGAIE-  240
            V R+ +RQW+L+ITA+A++LLE+L+E+DWPES+K++Q+NWIGKS+GA+V F   +   + 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  -VFTTRPDTLIGVSFLALAPEHPLVDLLTSDEQKAVVAQYIKETQSKSERDRISEMKTKS  299
             VFTTRPDTL+G ++  LAPEH+LVD +T+ +Q   VA+Y +++  KS+  R    K K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  300  GVFTGSYAKHPVTHELIPIWIADYVLMGFGSGAVMGVPAHDERDLLFAEQFNLPVVSVLN  359
            GV TGSYA +PV    +P+WIADYVL ++G+GA+M+VPAHDERD  FA QFNL +++VL+
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  360  EEGVCINSCCE-GFH-----LDGLSGEEAKQYVINFLEENHLGAAKIAYKLRDWLFSRQR  413
               V   +  E G+H     LDGL    A   +++ LE + +G  +++Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  414  YWGEPIPIIHFEDGSCrplrddelpllppeIQDYRPEGVGQGPLAKVREWVQVFDTETQR  473
            YWGEPIPIIH EDG+  ++ + ELPL+ P  +D RP G G++PLA+V +W++V   +  +
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  474  AGKRETHTMPQWAGSCWYYLRFCDAHNSAAPWAKEKEQYWMPVDLYIGGAEHAVLHLLYA  533
             G+RET+TMPQWAGS WYYLR+ D+HN+      E  + W+PVD+Y+GGAEHAVLHLLYA
Sbjct  484  -GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  534  RFWHQVFYEAGIVSTPEPFKKLVNQGLVLATSYRIPGKGYIYPETAKEENGK-WVAPSGE  592
            RFWH+V+Y+ G+V+T EPF+KL NQG++L+TSYR +  + +  +     +G      +GE
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  593  ELDVRQEKMSKSKLNGVDPQILIDEFGADAVRMYAMFSGPLDKNKLWSNQGVAGCRRFLN  652
            EL+    KMSKS  N V+P+ +++++GAD++R+Y MF GPLD +  WS++G+ G R+FL+
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  653  RFYEMVSSDRVKEDNNFEGLSLAHKLVQRVTDAIEKLSLNTIPSSFMEFINDFVK----L  708
            R Y ++++  + E+N+     + +  V+ VT+ ++++ +NT  + +M F+N   K    +
Sbjct  663  RVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLF  722

Query  709  AVYPKSAVEMAVRALAPIAPHISEELW-VLLGNSPGVQKSGWPSVLPEYLEEQTVTIVVQ  767
            + Y+K+ V++    +AP+APH++EELW  L +++ ++    WPS     L E+ V IVVQ
Sbjct  723  SDYAKGFVQL----IAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQ  778

Query  768  VNGKLRARLDIMKDASKEEV--LALARESASKYLEGCEVKKAIFVPARLVNFVV  819
            ++GK++A+L + KD S+EE+  +ALA E     + G ++ K I VP +LVN+V+
Sbjct  779  IKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

599) L2BCAN2_00213 in NC_020932


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  683 bits (2582),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 414/834 (50%), Positives = 598/834 (72%), Gaps = 22/834 (2%)

Query  3    YDPGLIEEKWQKFWKNEQVFKAEEDETKTKYYVLDMFPYPSGAGLHVGHLIGYTATDIVA  62
            YD   IE KWQ FW +++ FK+  D +K K+Y LDMFPYPSGAGLHVGH  GYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RCKRAQGFSVLHPMGWDSFGLPAEQYAIRTGTHPRETTEKNIANFKKQLTAMGFSYDESR  122
            R KRAQG +VLHPMGWD+FGLPAEQYA+ TG +P E T  NIANFK+Q+ A+GFSYD  R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EFATSDPEYYKWTQKLFLILYEKGLAYMADMAVNYCPELGTVLSNEEI-ENGFSVDGGYP  181
            E  T+DP+YYKWTQ +F  LYEKGLAY A+++VN   ELGT ++NEE+  +G S  GGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRMLRQWVLRITAFADQLLEGLDELDWPESVKQLQKNWIGKSSGASVNFATEHGAIE-  240
            V R+ +RQW+L+ITA+A++LLE+L+E+DWPES+K++Q+NWIGKS+GA+V F   +   + 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  -VFTTRPDTLIGVSFLALAPEHPLVDLLTSDEQKAVVAQYIKETQSKSERDRISEMKTKS  299
             VFTTRPDTL+G ++  LAPEH+LVD +T+ +Q   VA+Y +++  KS+  R    K K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  300  GVFTGSYAKHPVTHELIPIWIADYVLMGFGSGAVMGVPAHDERDLLFAEQFNLPVVSVLN  359
            GV TGSYA +PV    +P+WIADYVL ++G+GA+M+VPAHDERD  FA QFNL +++VL+
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  360  EEGVCINSCCE-GFH-----LDGLSGEEAKQYVINFLEENHLGAAKIAYKLRDWLFSRQR  413
               V   +  E G+H     LDGL    A   +++ LE + +G  +++Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  414  YWGEPIPIIHFEDGSCrplrddelpllppeIQDYRPEGVGQGPLAKVREWVQVFDTETQR  473
            YWGEPIPIIH EDG+  ++ + ELPL+ P  +D RP G G++PLA+V +W++V   +  +
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  474  AGKRETHTMPQWAGSCWYYLRFCDAHNSAAPWAKEKEQYWMPVDLYIGGAEHAVLHLLYA  533
             G+RET+TMPQWAGS WYYLR+ D+HN+      E  + W+PVD+Y+GGAEHAVLHLLYA
Sbjct  484  -GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  534  RFWHQVFYEAGIVSTPEPFKKLVNQGLVLATSYRIPGKGYIYPETAKEENGK-WVAPSGE  592
            RFWH+V+Y+ G+V+T EPF+KL NQG++L+TSYR +  + +  +     +G      +GE
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  593  ELDVRQEKMSKSKLNGVDPQILIDEFGADAVRMYAMFSGPLDKNKLWSNQGVAGCRRFLN  652
            EL+    KMSKS  N V+P+ +++++GAD++R+Y MF GPLD +  WS++G+ G R+FL+
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  653  RFYEMVSSDRVKEDNNFEGLSLAHKLVQRVTDAIEKLSLNTIPSSFMEFINDFVK----L  708
            R Y ++++  + E+N+     + +  V+ VT+ ++++ +NT  + +M F+N   K    +
Sbjct  663  RVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLF  722

Query  709  AVYPKSAVEMAVRALAPIAPHISEELW-VLLGNSPGVQKSGWPSVLPEYLEEQTVTIVVQ  767
            + Y+K+ V++    +AP+APH++EELW  L +++ ++    WPS     L E+ V IVVQ
Sbjct  723  SDYAKGFVQL----IAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQ  778

Query  768  VNGKLRARLDIMKDASKEEV--LALARESASKYLEGCEVKKAIFVPARLVNFVV  819
            ++GK++A+L + KD S+EE+  +ALA E     + G ++ K I VP +LVN+V+
Sbjct  779  IKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

600) L2BCV204_00212 in NC_020976


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  683 bits (2582),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 414/834 (50%), Positives = 598/834 (72%), Gaps = 22/834 (2%)

Query  3    YDPGLIEEKWQKFWKNEQVFKAEEDETKTKYYVLDMFPYPSGAGLHVGHLIGYTATDIVA  62
            YD   IE KWQ FW +++ FK+  D +K K+Y LDMFPYPSGAGLHVGH  GYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RCKRAQGFSVLHPMGWDSFGLPAEQYAIRTGTHPRETTEKNIANFKKQLTAMGFSYDESR  122
            R KRAQG +VLHPMGWD+FGLPAEQYA+ TG +P E T  NIANFK+Q+ A+GFSYD  R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EFATSDPEYYKWTQKLFLILYEKGLAYMADMAVNYCPELGTVLSNEEI-ENGFSVDGGYP  181
            E  T+DP+YYKWTQ +F  LYEKGLAY A+++VN   ELGT ++NEE+  +G S  GGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRMLRQWVLRITAFADQLLEGLDELDWPESVKQLQKNWIGKSSGASVNFATEHGAIE-  240
            V R+ +RQW+L+ITA+A++LLE+L+E+DWPES+K++Q+NWIGKS+GA+V F   +   + 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  -VFTTRPDTLIGVSFLALAPEHPLVDLLTSDEQKAVVAQYIKETQSKSERDRISEMKTKS  299
             VFTTRPDTL+G ++  LAPEH+LVD +T+ +Q   VA+Y +++  KS+  R    K K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  300  GVFTGSYAKHPVTHELIPIWIADYVLMGFGSGAVMGVPAHDERDLLFAEQFNLPVVSVLN  359
            GV TGSYA +PV    +P+WIADYVL ++G+GA+M+VPAHDERD  FA QFNL +++VL+
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  360  EEGVCINSCCE-GFH-----LDGLSGEEAKQYVINFLEENHLGAAKIAYKLRDWLFSRQR  413
               V   +  E G+H     LDGL    A   +++ LE + +G  +++Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  414  YWGEPIPIIHFEDGSCrplrddelpllppeIQDYRPEGVGQGPLAKVREWVQVFDTETQR  473
            YWGEPIPIIH EDG+  ++ + ELPL+ P  +D RP G G++PLA+V +W++V   +  +
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  474  AGKRETHTMPQWAGSCWYYLRFCDAHNSAAPWAKEKEQYWMPVDLYIGGAEHAVLHLLYA  533
             G+RET+TMPQWAGS WYYLR+ D+HN+      E  + W+PVD+Y+GGAEHAVLHLLYA
Sbjct  484  -GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  534  RFWHQVFYEAGIVSTPEPFKKLVNQGLVLATSYRIPGKGYIYPETAKEENGK-WVAPSGE  592
            RFWH+V+Y+ G+V+T EPF+KL NQG++L+TSYR +  + +  +     +G      +GE
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  593  ELDVRQEKMSKSKLNGVDPQILIDEFGADAVRMYAMFSGPLDKNKLWSNQGVAGCRRFLN  652
            EL+    KMSKS  N V+P+ +++++GAD++R+Y MF GPLD +  WS++G+ G R+FL+
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  653  RFYEMVSSDRVKEDNNFEGLSLAHKLVQRVTDAIEKLSLNTIPSSFMEFINDFVK----L  708
            R Y ++++  + E+N+     + +  V+ VT+ ++++ +NT  + +M F+N   K    +
Sbjct  663  RVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLF  722

Query  709  AVYPKSAVEMAVRALAPIAPHISEELW-VLLGNSPGVQKSGWPSVLPEYLEEQTVTIVVQ  767
            + Y+K+ V++    +AP+APH++EELW  L +++ ++    WPS     L E+ V IVVQ
Sbjct  723  SDYAKGFVQL----IAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQ  778

Query  768  VNGKLRARLDIMKDASKEEV--LALARESASKYLEGCEVKKAIFVPARLVNFVV  819
            ++GK++A+L + KD S+EE+  +ALA E     + G ++ K I VP +LVN+V+
Sbjct  779  IKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

601) leuS in NC_010280


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  683 bits (2582),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 414/834 (50%), Positives = 598/834 (72%), Gaps = 22/834 (2%)

Query  3    YDPGLIEEKWQKFWKNEQVFKAEEDETKTKYYVLDMFPYPSGAGLHVGHLIGYTATDIVA  62
            YD   IE KWQ FW +++ FK+  D +K K+Y LDMFPYPSGAGLHVGH  GYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RCKRAQGFSVLHPMGWDSFGLPAEQYAIRTGTHPRETTEKNIANFKKQLTAMGFSYDESR  122
            R KRAQG +VLHPMGWD+FGLPAEQYA+ TG +P E T  NIANFK+Q+ A+GFSYD  R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EFATSDPEYYKWTQKLFLILYEKGLAYMADMAVNYCPELGTVLSNEEI-ENGFSVDGGYP  181
            E  T+DP+YYKWTQ +F  LYEKGLAY A+++VN   ELGT ++NEE+  +G S  GGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRMLRQWVLRITAFADQLLEGLDELDWPESVKQLQKNWIGKSSGASVNFATEHGAIE-  240
            V R+ +RQW+L+ITA+A++LLE+L+E+DWPES+K++Q+NWIGKS+GA+V F   +   + 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  -VFTTRPDTLIGVSFLALAPEHPLVDLLTSDEQKAVVAQYIKETQSKSERDRISEMKTKS  299
             VFTTRPDTL+G ++  LAPEH+LVD +T+ +Q   VA+Y +++  KS+  R    K K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  300  GVFTGSYAKHPVTHELIPIWIADYVLMGFGSGAVMGVPAHDERDLLFAEQFNLPVVSVLN  359
            GV TGSYA +PV    +P+WIADYVL ++G+GA+M+VPAHDERD  FA QFNL +++VL+
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  360  EEGVCINSCCE-GFH-----LDGLSGEEAKQYVINFLEENHLGAAKIAYKLRDWLFSRQR  413
               V   +  E G+H     LDGL    A   +++ LE + +G  +++Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  414  YWGEPIPIIHFEDGSCrplrddelpllppeIQDYRPEGVGQGPLAKVREWVQVFDTETQR  473
            YWGEPIPIIH EDG+  ++ + ELPL+ P  +D RP G G++PLA+V +W++V   +  +
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  474  AGKRETHTMPQWAGSCWYYLRFCDAHNSAAPWAKEKEQYWMPVDLYIGGAEHAVLHLLYA  533
             G+RET+TMPQWAGS WYYLR+ D+HN+      E  + W+PVD+Y+GGAEHAVLHLLYA
Sbjct  484  -GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  534  RFWHQVFYEAGIVSTPEPFKKLVNQGLVLATSYRIPGKGYIYPETAKEENGK-WVAPSGE  592
            RFWH+V+Y+ G+V+T EPF+KL NQG++L+TSYR +  + +  +     +G      +GE
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  593  ELDVRQEKMSKSKLNGVDPQILIDEFGADAVRMYAMFSGPLDKNKLWSNQGVAGCRRFLN  652
            EL+    KMSKS  N V+P+ +++++GAD++R+Y MF GPLD +  WS++G+ G R+FL+
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  653  RFYEMVSSDRVKEDNNFEGLSLAHKLVQRVTDAIEKLSLNTIPSSFMEFINDFVK----L  708
            R Y ++++  + E+N+     + +  V+ VT+ ++++ +NT  + +M F+N   K    +
Sbjct  663  RVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLF  722

Query  709  AVYPKSAVEMAVRALAPIAPHISEELW-VLLGNSPGVQKSGWPSVLPEYLEEQTVTIVVQ  767
            + Y+K+ V++    +AP+APH++EELW  L +++ ++    WPS     L E+ V IVVQ
Sbjct  723  SDYAKGFVQL----IAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQ  778

Query  768  VNGKLRARLDIMKDASKEEV--LALARESASKYLEGCEVKKAIFVPARLVNFVV  819
            ++GK++A+L + KD S+EE+  +ALA E     + G ++ K I VP +LVN+V+
Sbjct  779  IKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

602) L2BUCH2_00212 in NC_020931


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  683 bits (2582),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 414/834 (50%), Positives = 598/834 (72%), Gaps = 22/834 (2%)

Query  3    YDPGLIEEKWQKFWKNEQVFKAEEDETKTKYYVLDMFPYPSGAGLHVGHLIGYTATDIVA  62
            YD   IE KWQ FW +++ FK+  D +K K+Y LDMFPYPSGAGLHVGH  GYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RCKRAQGFSVLHPMGWDSFGLPAEQYAIRTGTHPRETTEKNIANFKKQLTAMGFSYDESR  122
            R KRAQG +VLHPMGWD+FGLPAEQYA+ TG +P E T  NIANFK+Q+ A+GFSYD  R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EFATSDPEYYKWTQKLFLILYEKGLAYMADMAVNYCPELGTVLSNEEI-ENGFSVDGGYP  181
            E  T+DP+YYKWTQ +F  LYEKGLAY A+++VN   ELGT ++NEE+  +G S  GGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRMLRQWVLRITAFADQLLEGLDELDWPESVKQLQKNWIGKSSGASVNFATEHGAIE-  240
            V R+ +RQW+L+ITA+A++LLE+L+E+DWPES+K++Q+NWIGKS+GA+V F   +   + 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  -VFTTRPDTLIGVSFLALAPEHPLVDLLTSDEQKAVVAQYIKETQSKSERDRISEMKTKS  299
             VFTTRPDTL+G ++  LAPEH+LVD +T+ +Q   VA+Y +++  KS+  R    K K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  300  GVFTGSYAKHPVTHELIPIWIADYVLMGFGSGAVMGVPAHDERDLLFAEQFNLPVVSVLN  359
            GV TGSYA +PV    +P+WIADYVL ++G+GA+M+VPAHDERD  FA QFNL +++VL+
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  360  EEGVCINSCCE-GFH-----LDGLSGEEAKQYVINFLEENHLGAAKIAYKLRDWLFSRQR  413
               V   +  E G+H     LDGL    A   +++ LE + +G  +++Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  414  YWGEPIPIIHFEDGSCrplrddelpllppeIQDYRPEGVGQGPLAKVREWVQVFDTETQR  473
            YWGEPIPIIH EDG+  ++ + ELPL+ P  +D RP G G++PLA+V +W++V   +  +
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  474  AGKRETHTMPQWAGSCWYYLRFCDAHNSAAPWAKEKEQYWMPVDLYIGGAEHAVLHLLYA  533
             G+RET+TMPQWAGS WYYLR+ D+HN+      E  + W+PVD+Y+GGAEHAVLHLLYA
Sbjct  484  -GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  534  RFWHQVFYEAGIVSTPEPFKKLVNQGLVLATSYRIPGKGYIYPETAKEENGK-WVAPSGE  592
            RFWH+V+Y+ G+V+T EPF+KL NQG++L+TSYR +  + +  +     +G      +GE
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  593  ELDVRQEKMSKSKLNGVDPQILIDEFGADAVRMYAMFSGPLDKNKLWSNQGVAGCRRFLN  652
            EL+    KMSKS  N V+P+ +++++GAD++R+Y MF GPLD +  WS++G+ G R+FL+
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  653  RFYEMVSSDRVKEDNNFEGLSLAHKLVQRVTDAIEKLSLNTIPSSFMEFINDFVK----L  708
            R Y ++++  + E+N+     + +  V+ VT+ ++++ +NT  + +M F+N   K    +
Sbjct  663  RVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLF  722

Query  709  AVYPKSAVEMAVRALAPIAPHISEELW-VLLGNSPGVQKSGWPSVLPEYLEEQTVTIVVQ  767
            + Y+K+ V++    +AP+APH++EELW  L +++ ++    WPS     L E+ V IVVQ
Sbjct  723  SDYAKGFVQL----IAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQ  778

Query  768  VNGKLRARLDIMKDASKEEV--LALARESASKYLEGCEVKKAIFVPARLVNFVV  819
            ++GK++A+L + KD S+EE+  +ALA E     + G ++ K I VP +LVN+V+
Sbjct  779  IKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

603) leuS in NC_015744


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  683 bits (2582),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 414/834 (50%), Positives = 598/834 (72%), Gaps = 22/834 (2%)

Query  3    YDPGLIEEKWQKFWKNEQVFKAEEDETKTKYYVLDMFPYPSGAGLHVGHLIGYTATDIVA  62
            YD   IE KWQ FW +++ FK+  D +K K+Y LDMFPYPSGAGLHVGH  GYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RCKRAQGFSVLHPMGWDSFGLPAEQYAIRTGTHPRETTEKNIANFKKQLTAMGFSYDESR  122
            R KRAQG +VLHPMGWD+FGLPAEQYA+ TG +P E T  NIANFK+Q+ A+GFSYD  R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EFATSDPEYYKWTQKLFLILYEKGLAYMADMAVNYCPELGTVLSNEEI-ENGFSVDGGYP  181
            E  T+DP+YYKWTQ +F  LYEKGLAY A+++VN   ELGT ++NEE+  +G S  GGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRMLRQWVLRITAFADQLLEGLDELDWPESVKQLQKNWIGKSSGASVNFATEHGAIE-  240
            V R+ +RQW+L+ITA+A++LLE+L+E+DWPES+K++Q+NWIGKS+GA+V F   +   + 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  -VFTTRPDTLIGVSFLALAPEHPLVDLLTSDEQKAVVAQYIKETQSKSERDRISEMKTKS  299
             VFTTRPDTL+G ++  LAPEH+LVD +T+ +Q   VA+Y +++  KS+  R    K K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  300  GVFTGSYAKHPVTHELIPIWIADYVLMGFGSGAVMGVPAHDERDLLFAEQFNLPVVSVLN  359
            GV TGSYA +PV    +P+WIADYVL ++G+GA+M+VPAHDERD  FA QFNL +++VL+
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  360  EEGVCINSCCE-GFH-----LDGLSGEEAKQYVINFLEENHLGAAKIAYKLRDWLFSRQR  413
               V   +  E G+H     LDGL    A   +++ LE + +G  +++Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  414  YWGEPIPIIHFEDGSCrplrddelpllppeIQDYRPEGVGQGPLAKVREWVQVFDTETQR  473
            YWGEPIPIIH EDG+  ++ + ELPL+ P  +D RP G G++PLA+V +W++V   +  +
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  474  AGKRETHTMPQWAGSCWYYLRFCDAHNSAAPWAKEKEQYWMPVDLYIGGAEHAVLHLLYA  533
             G+RET+TMPQWAGS WYYLR+ D+HN+      E  + W+PVD+Y+GGAEHAVLHLLYA
Sbjct  484  -GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  534  RFWHQVFYEAGIVSTPEPFKKLVNQGLVLATSYRIPGKGYIYPETAKEENGK-WVAPSGE  592
            RFWH+V+Y+ G+V+T EPF+KL NQG++L+TSYR +  + +  +     +G      +GE
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  593  ELDVRQEKMSKSKLNGVDPQILIDEFGADAVRMYAMFSGPLDKNKLWSNQGVAGCRRFLN  652
            EL+    KMSKS  N V+P+ +++++GAD++R+Y MF GPLD +  WS++G+ G R+FL+
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  653  RFYEMVSSDRVKEDNNFEGLSLAHKLVQRVTDAIEKLSLNTIPSSFMEFINDFVK----L  708
            R Y ++++  + E+N+     + +  V+ VT+ ++++ +NT  + +M F+N   K    +
Sbjct  663  RVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLF  722

Query  709  AVYPKSAVEMAVRALAPIAPHISEELW-VLLGNSPGVQKSGWPSVLPEYLEEQTVTIVVQ  767
            + Y+K+ V++    +AP+APH++EELW  L +++ ++    WPS     L E+ V IVVQ
Sbjct  723  SDYAKGFVQL----IAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQ  778

Query  768  VNGKLRARLDIMKDASKEEV--LALARESASKYLEGCEVKKAIFVPARLVNFVV  819
            ++GK++A+L + KD S+EE+  +ALA E     + G ++ K I VP +LVN+V+
Sbjct  779  IKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

604) L3404_00212 in NC_020974


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  683 bits (2582),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 414/834 (50%), Positives = 598/834 (72%), Gaps = 22/834 (2%)

Query  3    YDPGLIEEKWQKFWKNEQVFKAEEDETKTKYYVLDMFPYPSGAGLHVGHLIGYTATDIVA  62
            YD   IE KWQ FW +++ FK+  D +K K+Y LDMFPYPSGAGLHVGH  GYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RCKRAQGFSVLHPMGWDSFGLPAEQYAIRTGTHPRETTEKNIANFKKQLTAMGFSYDESR  122
            R KRAQG +VLHPMGWD+FGLPAEQYA+ TG +P E T  NIANFK+Q+ A+GFSYD  R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EFATSDPEYYKWTQKLFLILYEKGLAYMADMAVNYCPELGTVLSNEEI-ENGFSVDGGYP  181
            E  T+DP+YYKWTQ +F  LYEKGLAY A+++VN   ELGT ++NEE+  +G S  GGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRMLRQWVLRITAFADQLLEGLDELDWPESVKQLQKNWIGKSSGASVNFATEHGAIE-  240
            V R+ +RQW+L+ITA+A++LLE+L+E+DWPES+K++Q+NWIGKS+GA+V F   +   + 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  -VFTTRPDTLIGVSFLALAPEHPLVDLLTSDEQKAVVAQYIKETQSKSERDRISEMKTKS  299
             VFTTRPDTL+G ++  LAPEH+LVD +T+ +Q   VA+Y +++  KS+  R    K K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  300  GVFTGSYAKHPVTHELIPIWIADYVLMGFGSGAVMGVPAHDERDLLFAEQFNLPVVSVLN  359
            GV TGSYA +PV    +P+WIADYVL ++G+GA+M+VPAHDERD  FA QFNL +++VL+
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  360  EEGVCINSCCE-GFH-----LDGLSGEEAKQYVINFLEENHLGAAKIAYKLRDWLFSRQR  413
               V   +  E G+H     LDGL    A   +++ LE + +G  +++Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  414  YWGEPIPIIHFEDGSCrplrddelpllppeIQDYRPEGVGQGPLAKVREWVQVFDTETQR  473
            YWGEPIPIIH EDG+  ++ + ELPL+ P  +D RP G G++PLA+V +W++V   +  +
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  474  AGKRETHTMPQWAGSCWYYLRFCDAHNSAAPWAKEKEQYWMPVDLYIGGAEHAVLHLLYA  533
             G+RET+TMPQWAGS WYYLR+ D+HN+      E  + W+PVD+Y+GGAEHAVLHLLYA
Sbjct  484  -GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  534  RFWHQVFYEAGIVSTPEPFKKLVNQGLVLATSYRIPGKGYIYPETAKEENGK-WVAPSGE  592
            RFWH+V+Y+ G+V+T EPF+KL NQG++L+TSYR +  + +  +     +G      +GE
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  593  ELDVRQEKMSKSKLNGVDPQILIDEFGADAVRMYAMFSGPLDKNKLWSNQGVAGCRRFLN  652
            EL+    KMSKS  N V+P+ +++++GAD++R+Y MF GPLD +  WS++G+ G R+FL+
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  653  RFYEMVSSDRVKEDNNFEGLSLAHKLVQRVTDAIEKLSLNTIPSSFMEFINDFVK----L  708
            R Y ++++  + E+N+     + +  V+ VT+ ++++ +NT  + +M F+N   K    +
Sbjct  663  RVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLF  722

Query  709  AVYPKSAVEMAVRALAPIAPHISEELW-VLLGNSPGVQKSGWPSVLPEYLEEQTVTIVVQ  767
            + Y+K+ V++    +AP+APH++EELW  L +++ ++    WPS     L E+ V IVVQ
Sbjct  723  SDYAKGFVQL----IAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQ  778

Query  768  VNGKLRARLDIMKDASKEEV--LALARESASKYLEGCEVKKAIFVPARLVNFVV  819
            ++GK++A+L + KD S+EE+  +ALA E     + G ++ K I VP +LVN+V+
Sbjct  779  IKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

605) leuS in NC_021895


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  683 bits (2582),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 414/834 (50%), Positives = 598/834 (72%), Gaps = 22/834 (2%)

Query  3    YDPGLIEEKWQKFWKNEQVFKAEEDETKTKYYVLDMFPYPSGAGLHVGHLIGYTATDIVA  62
            YD   IE KWQ FW +++ FK+  D +K K+Y LDMFPYPSGAGLHVGH  GYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RCKRAQGFSVLHPMGWDSFGLPAEQYAIRTGTHPRETTEKNIANFKKQLTAMGFSYDESR  122
            R KRAQG +VLHPMGWD+FGLPAEQYA+ TG +P E T  NIANFK+Q+ A+GFSYD  R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EFATSDPEYYKWTQKLFLILYEKGLAYMADMAVNYCPELGTVLSNEEI-ENGFSVDGGYP  181
            E  T+DP+YYKWTQ +F  LYEKGLAY A+++VN   ELGT ++NEE+  +G S  GGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRMLRQWVLRITAFADQLLEGLDELDWPESVKQLQKNWIGKSSGASVNFATEHGAIE-  240
            V R+ +RQW+L+ITA+A++LLE+L+E+DWPES+K++Q+NWIGKS+GA+V F   +   + 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  -VFTTRPDTLIGVSFLALAPEHPLVDLLTSDEQKAVVAQYIKETQSKSERDRISEMKTKS  299
             VFTTRPDTL+G ++  LAPEH+LVD +T+ +Q   VA+Y +++  KS+  R    K K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  300  GVFTGSYAKHPVTHELIPIWIADYVLMGFGSGAVMGVPAHDERDLLFAEQFNLPVVSVLN  359
            GV TGSYA +PV    +P+WIADYVL ++G+GA+M+VPAHDERD  FA QFNL +++VL+
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  360  EEGVCINSCCE-GFH-----LDGLSGEEAKQYVINFLEENHLGAAKIAYKLRDWLFSRQR  413
               V   +  E G+H     LDGL    A   +++ LE + +G  +++Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  414  YWGEPIPIIHFEDGSCrplrddelpllppeIQDYRPEGVGQGPLAKVREWVQVFDTETQR  473
            YWGEPIPIIH EDG+  ++ + ELPL+ P  +D RP G G++PLA+V +W++V   +  +
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  474  AGKRETHTMPQWAGSCWYYLRFCDAHNSAAPWAKEKEQYWMPVDLYIGGAEHAVLHLLYA  533
             G+RET+TMPQWAGS WYYLR+ D+HN+      E  + W+PVD+Y+GGAEHAVLHLLYA
Sbjct  484  -GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  534  RFWHQVFYEAGIVSTPEPFKKLVNQGLVLATSYRIPGKGYIYPETAKEENGK-WVAPSGE  592
            RFWH+V+Y+ G+V+T EPF+KL NQG++L+TSYR +  + +  +     +G      +GE
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  593  ELDVRQEKMSKSKLNGVDPQILIDEFGADAVRMYAMFSGPLDKNKLWSNQGVAGCRRFLN  652
            EL+    KMSKS  N V+P+ +++++GAD++R+Y MF GPLD +  WS++G+ G R+FL+
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  653  RFYEMVSSDRVKEDNNFEGLSLAHKLVQRVTDAIEKLSLNTIPSSFMEFINDFVK----L  708
            R Y ++++  + E+N+     + +  V+ VT+ ++++ +NT  + +M F+N   K    +
Sbjct  663  RVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLF  722

Query  709  AVYPKSAVEMAVRALAPIAPHISEELW-VLLGNSPGVQKSGWPSVLPEYLEEQTVTIVVQ  767
            + Y+K+ V++    +AP+APH++EELW  L +++ ++    WPS     L E+ V IVVQ
Sbjct  723  SDYAKGFVQL----IAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQ  778

Query  768  VNGKLRARLDIMKDASKEEV--LALARESASKYLEGCEVKKAIFVPARLVNFVV  819
            ++GK++A+L + KD S+EE+  +ALA E     + G ++ K I VP +LVN+V+
Sbjct  779  IKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

606) leuS in NC_021896


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  683 bits (2582),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 414/834 (50%), Positives = 598/834 (72%), Gaps = 22/834 (2%)

Query  3    YDPGLIEEKWQKFWKNEQVFKAEEDETKTKYYVLDMFPYPSGAGLHVGHLIGYTATDIVA  62
            YD   IE KWQ FW +++ FK+  D +K K+Y LDMFPYPSGAGLHVGH  GYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RCKRAQGFSVLHPMGWDSFGLPAEQYAIRTGTHPRETTEKNIANFKKQLTAMGFSYDESR  122
            R KRAQG +VLHPMGWD+FGLPAEQYA+ TG +P E T  NIANFK+Q+ A+GFSYD  R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EFATSDPEYYKWTQKLFLILYEKGLAYMADMAVNYCPELGTVLSNEEI-ENGFSVDGGYP  181
            E  T+DP+YYKWTQ +F  LYEKGLAY A+++VN   ELGT ++NEE+  +G S  GGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRMLRQWVLRITAFADQLLEGLDELDWPESVKQLQKNWIGKSSGASVNFATEHGAIE-  240
            V R+ +RQW+L+ITA+A++LLE+L+E+DWPES+K++Q+NWIGKS+GA+V F   +   + 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  -VFTTRPDTLIGVSFLALAPEHPLVDLLTSDEQKAVVAQYIKETQSKSERDRISEMKTKS  299
             VFTTRPDTL+G ++  LAPEH+LVD +T+ +Q   VA+Y +++  KS+  R    K K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  300  GVFTGSYAKHPVTHELIPIWIADYVLMGFGSGAVMGVPAHDERDLLFAEQFNLPVVSVLN  359
            GV TGSYA +PV    +P+WIADYVL ++G+GA+M+VPAHDERD  FA QFNL +++VL+
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  360  EEGVCINSCCE-GFH-----LDGLSGEEAKQYVINFLEENHLGAAKIAYKLRDWLFSRQR  413
               V   +  E G+H     LDGL    A   +++ LE + +G  +++Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  414  YWGEPIPIIHFEDGSCrplrddelpllppeIQDYRPEGVGQGPLAKVREWVQVFDTETQR  473
            YWGEPIPIIH EDG+  ++ + ELPL+ P  +D RP G G++PLA+V +W++V   +  +
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  474  AGKRETHTMPQWAGSCWYYLRFCDAHNSAAPWAKEKEQYWMPVDLYIGGAEHAVLHLLYA  533
             G+RET+TMPQWAGS WYYLR+ D+HN+      E  + W+PVD+Y+GGAEHAVLHLLYA
Sbjct  484  -GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  534  RFWHQVFYEAGIVSTPEPFKKLVNQGLVLATSYRIPGKGYIYPETAKEENGK-WVAPSGE  592
            RFWH+V+Y+ G+V+T EPF+KL NQG++L+TSYR +  + +  +     +G      +GE
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  593  ELDVRQEKMSKSKLNGVDPQILIDEFGADAVRMYAMFSGPLDKNKLWSNQGVAGCRRFLN  652
            EL+    KMSKS  N V+P+ +++++GAD++R+Y MF GPLD +  WS++G+ G R+FL+
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  653  RFYEMVSSDRVKEDNNFEGLSLAHKLVQRVTDAIEKLSLNTIPSSFMEFINDFVK----L  708
            R Y ++++  + E+N+     + +  V+ VT+ ++++ +NT  + +M F+N   K    +
Sbjct  663  RVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLF  722

Query  709  AVYPKSAVEMAVRALAPIAPHISEELW-VLLGNSPGVQKSGWPSVLPEYLEEQTVTIVVQ  767
            + Y+K+ V++    +AP+APH++EELW  L +++ ++    WPS     L E+ V IVVQ
Sbjct  723  SDYAKGFVQL----IAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQ  778

Query  768  VNGKLRARLDIMKDASKEEV--LALARESASKYLEGCEVKKAIFVPARLVNFVV  819
            ++GK++A+L + KD S+EE+  +ALA E     + G ++ K I VP +LVN+V+
Sbjct  779  IKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

607) leuS in NC_021889


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  683 bits (2582),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 414/834 (50%), Positives = 598/834 (72%), Gaps = 22/834 (2%)

Query  3    YDPGLIEEKWQKFWKNEQVFKAEEDETKTKYYVLDMFPYPSGAGLHVGHLIGYTATDIVA  62
            YD   IE KWQ FW +++ FK+  D +K K+Y LDMFPYPSGAGLHVGH  GYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RCKRAQGFSVLHPMGWDSFGLPAEQYAIRTGTHPRETTEKNIANFKKQLTAMGFSYDESR  122
            R KRAQG +VLHPMGWD+FGLPAEQYA+ TG +P E T  NIANFK+Q+ A+GFSYD  R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EFATSDPEYYKWTQKLFLILYEKGLAYMADMAVNYCPELGTVLSNEEI-ENGFSVDGGYP  181
            E  T+DP+YYKWTQ +F  LYEKGLAY A+++VN   ELGT ++NEE+  +G S  GGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRMLRQWVLRITAFADQLLEGLDELDWPESVKQLQKNWIGKSSGASVNFATEHGAIE-  240
            V R+ +RQW+L+ITA+A++LLE+L+E+DWPES+K++Q+NWIGKS+GA+V F   +   + 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  -VFTTRPDTLIGVSFLALAPEHPLVDLLTSDEQKAVVAQYIKETQSKSERDRISEMKTKS  299
             VFTTRPDTL+G ++  LAPEH+LVD +T+ +Q   VA+Y +++  KS+  R    K K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  300  GVFTGSYAKHPVTHELIPIWIADYVLMGFGSGAVMGVPAHDERDLLFAEQFNLPVVSVLN  359
            GV TGSYA +PV    +P+WIADYVL ++G+GA+M+VPAHDERD  FA QFNL +++VL+
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  360  EEGVCINSCCE-GFH-----LDGLSGEEAKQYVINFLEENHLGAAKIAYKLRDWLFSRQR  413
               V   +  E G+H     LDGL    A   +++ LE + +G  +++Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  414  YWGEPIPIIHFEDGSCrplrddelpllppeIQDYRPEGVGQGPLAKVREWVQVFDTETQR  473
            YWGEPIPIIH EDG+  ++ + ELPL+ P  +D RP G G++PLA+V +W++V   +  +
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  474  AGKRETHTMPQWAGSCWYYLRFCDAHNSAAPWAKEKEQYWMPVDLYIGGAEHAVLHLLYA  533
             G+RET+TMPQWAGS WYYLR+ D+HN+      E  + W+PVD+Y+GGAEHAVLHLLYA
Sbjct  484  -GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  534  RFWHQVFYEAGIVSTPEPFKKLVNQGLVLATSYRIPGKGYIYPETAKEENGK-WVAPSGE  592
            RFWH+V+Y+ G+V+T EPF+KL NQG++L+TSYR +  + +  +     +G      +GE
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  593  ELDVRQEKMSKSKLNGVDPQILIDEFGADAVRMYAMFSGPLDKNKLWSNQGVAGCRRFLN  652
            EL+    KMSKS  N V+P+ +++++GAD++R+Y MF GPLD +  WS++G+ G R+FL+
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  653  RFYEMVSSDRVKEDNNFEGLSLAHKLVQRVTDAIEKLSLNTIPSSFMEFINDFVK----L  708
            R Y ++++  + E+N+     + +  V+ VT+ ++++ +NT  + +M F+N   K    +
Sbjct  663  RVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLF  722

Query  709  AVYPKSAVEMAVRALAPIAPHISEELW-VLLGNSPGVQKSGWPSVLPEYLEEQTVTIVVQ  767
            + Y+K+ V++    +AP+APH++EELW  L +++ ++    WPS     L E+ V IVVQ
Sbjct  723  SDYAKGFVQL----IAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQ  778

Query  768  VNGKLRARLDIMKDASKEEV--LALARESASKYLEGCEVKKAIFVPARLVNFVV  819
            ++GK++A+L + KD S+EE+  +ALA E     + G ++ K I VP +LVN+V+
Sbjct  779  IKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

608) leuS in NC_021898


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  683 bits (2582),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 414/834 (50%), Positives = 598/834 (72%), Gaps = 22/834 (2%)

Query  3    YDPGLIEEKWQKFWKNEQVFKAEEDETKTKYYVLDMFPYPSGAGLHVGHLIGYTATDIVA  62
            YD   IE KWQ FW +++ FK+  D +K K+Y LDMFPYPSGAGLHVGH  GYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RCKRAQGFSVLHPMGWDSFGLPAEQYAIRTGTHPRETTEKNIANFKKQLTAMGFSYDESR  122
            R KRAQG +VLHPMGWD+FGLPAEQYA+ TG +P E T  NIANFK+Q+ A+GFSYD  R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EFATSDPEYYKWTQKLFLILYEKGLAYMADMAVNYCPELGTVLSNEEI-ENGFSVDGGYP  181
            E  T+DP+YYKWTQ +F  LYEKGLAY A+++VN   ELGT ++NEE+  +G S  GGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRMLRQWVLRITAFADQLLEGLDELDWPESVKQLQKNWIGKSSGASVNFATEHGAIE-  240
            V R+ +RQW+L+ITA+A++LLE+L+E+DWPES+K++Q+NWIGKS+GA+V F   +   + 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  -VFTTRPDTLIGVSFLALAPEHPLVDLLTSDEQKAVVAQYIKETQSKSERDRISEMKTKS  299
             VFTTRPDTL+G ++  LAPEH+LVD +T+ +Q   VA+Y +++  KS+  R    K K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  300  GVFTGSYAKHPVTHELIPIWIADYVLMGFGSGAVMGVPAHDERDLLFAEQFNLPVVSVLN  359
            GV TGSYA +PV    +P+WIADYVL ++G+GA+M+VPAHDERD  FA QFNL +++VL+
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  360  EEGVCINSCCE-GFH-----LDGLSGEEAKQYVINFLEENHLGAAKIAYKLRDWLFSRQR  413
               V   +  E G+H     LDGL    A   +++ LE + +G  +++Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  414  YWGEPIPIIHFEDGSCrplrddelpllppeIQDYRPEGVGQGPLAKVREWVQVFDTETQR  473
            YWGEPIPIIH EDG+  ++ + ELPL+ P  +D RP G G++PLA+V +W++V   +  +
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  474  AGKRETHTMPQWAGSCWYYLRFCDAHNSAAPWAKEKEQYWMPVDLYIGGAEHAVLHLLYA  533
             G+RET+TMPQWAGS WYYLR+ D+HN+      E  + W+PVD+Y+GGAEHAVLHLLYA
Sbjct  484  -GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  534  RFWHQVFYEAGIVSTPEPFKKLVNQGLVLATSYRIPGKGYIYPETAKEENGK-WVAPSGE  592
            RFWH+V+Y+ G+V+T EPF+KL NQG++L+TSYR +  + +  +     +G      +GE
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  593  ELDVRQEKMSKSKLNGVDPQILIDEFGADAVRMYAMFSGPLDKNKLWSNQGVAGCRRFLN  652
            EL+    KMSKS  N V+P+ +++++GAD++R+Y MF GPLD +  WS++G+ G R+FL+
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  653  RFYEMVSSDRVKEDNNFEGLSLAHKLVQRVTDAIEKLSLNTIPSSFMEFINDFVK----L  708
            R Y ++++  + E+N+     + +  V+ VT+ ++++ +NT  + +M F+N   K    +
Sbjct  663  RVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLF  722

Query  709  AVYPKSAVEMAVRALAPIAPHISEELW-VLLGNSPGVQKSGWPSVLPEYLEEQTVTIVVQ  767
            + Y+K+ V++    +AP+APH++EELW  L +++ ++    WPS     L E+ V IVVQ
Sbjct  723  SDYAKGFVQL----IAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQ  778

Query  768  VNGKLRARLDIMKDASKEEV--LALARESASKYLEGCEVKKAIFVPARLVNFVV  819
            ++GK++A+L + KD S+EE+  +ALA E     + G ++ K I VP +LVN+V+
Sbjct  779  IKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

609) leuS in NC_021899


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  683 bits (2582),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 414/834 (50%), Positives = 598/834 (72%), Gaps = 22/834 (2%)

Query  3    YDPGLIEEKWQKFWKNEQVFKAEEDETKTKYYVLDMFPYPSGAGLHVGHLIGYTATDIVA  62
            YD   IE KWQ FW +++ FK+  D +K K+Y LDMFPYPSGAGLHVGH  GYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RCKRAQGFSVLHPMGWDSFGLPAEQYAIRTGTHPRETTEKNIANFKKQLTAMGFSYDESR  122
            R KRAQG +VLHPMGWD+FGLPAEQYA+ TG +P E T  NIANFK+Q+ A+GFSYD  R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EFATSDPEYYKWTQKLFLILYEKGLAYMADMAVNYCPELGTVLSNEEI-ENGFSVDGGYP  181
            E  T+DP+YYKWTQ +F  LYEKGLAY A+++VN   ELGT ++NEE+  +G S  GGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRMLRQWVLRITAFADQLLEGLDELDWPESVKQLQKNWIGKSSGASVNFATEHGAIE-  240
            V R+ +RQW+L+ITA+A++LLE+L+E+DWPES+K++Q+NWIGKS+GA+V F   +   + 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  -VFTTRPDTLIGVSFLALAPEHPLVDLLTSDEQKAVVAQYIKETQSKSERDRISEMKTKS  299
             VFTTRPDTL+G ++  LAPEH+LVD +T+ +Q   VA+Y +++  KS+  R    K K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  300  GVFTGSYAKHPVTHELIPIWIADYVLMGFGSGAVMGVPAHDERDLLFAEQFNLPVVSVLN  359
            GV TGSYA +PV    +P+WIADYVL ++G+GA+M+VPAHDERD  FA QFNL +++VL+
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  360  EEGVCINSCCE-GFH-----LDGLSGEEAKQYVINFLEENHLGAAKIAYKLRDWLFSRQR  413
               V   +  E G+H     LDGL    A   +++ LE + +G  +++Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  414  YWGEPIPIIHFEDGSCrplrddelpllppeIQDYRPEGVGQGPLAKVREWVQVFDTETQR  473
            YWGEPIPIIH EDG+  ++ + ELPL+ P  +D RP G G++PLA+V +W++V   +  +
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  474  AGKRETHTMPQWAGSCWYYLRFCDAHNSAAPWAKEKEQYWMPVDLYIGGAEHAVLHLLYA  533
             G+RET+TMPQWAGS WYYLR+ D+HN+      E  + W+PVD+Y+GGAEHAVLHLLYA
Sbjct  484  -GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  534  RFWHQVFYEAGIVSTPEPFKKLVNQGLVLATSYRIPGKGYIYPETAKEENGK-WVAPSGE  592
            RFWH+V+Y+ G+V+T EPF+KL NQG++L+TSYR +  + +  +     +G      +GE
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  593  ELDVRQEKMSKSKLNGVDPQILIDEFGADAVRMYAMFSGPLDKNKLWSNQGVAGCRRFLN  652
            EL+    KMSKS  N V+P+ +++++GAD++R+Y MF GPLD +  WS++G+ G R+FL+
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  653  RFYEMVSSDRVKEDNNFEGLSLAHKLVQRVTDAIEKLSLNTIPSSFMEFINDFVK----L  708
            R Y ++++  + E+N+     + +  V+ VT+ ++++ +NT  + +M F+N   K    +
Sbjct  663  RVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLF  722

Query  709  AVYPKSAVEMAVRALAPIAPHISEELW-VLLGNSPGVQKSGWPSVLPEYLEEQTVTIVVQ  767
            + Y+K+ V++    +AP+APH++EELW  L +++ ++    WPS     L E+ V IVVQ
Sbjct  723  SDYAKGFVQL----IAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQ  778

Query  768  VNGKLRARLDIMKDASKEEV--LALARESASKYLEGCEVKKAIFVPARLVNFVV  819
            ++GK++A+L + KD S+EE+  +ALA E     + G ++ K I VP +LVN+V+
Sbjct  779  IKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

610) leuS in NC_021891


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  683 bits (2582),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 414/834 (50%), Positives = 598/834 (72%), Gaps = 22/834 (2%)

Query  3    YDPGLIEEKWQKFWKNEQVFKAEEDETKTKYYVLDMFPYPSGAGLHVGHLIGYTATDIVA  62
            YD   IE KWQ FW +++ FK+  D +K K+Y LDMFPYPSGAGLHVGH  GYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RCKRAQGFSVLHPMGWDSFGLPAEQYAIRTGTHPRETTEKNIANFKKQLTAMGFSYDESR  122
            R KRAQG +VLHPMGWD+FGLPAEQYA+ TG +P E T  NIANFK+Q+ A+GFSYD  R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EFATSDPEYYKWTQKLFLILYEKGLAYMADMAVNYCPELGTVLSNEEI-ENGFSVDGGYP  181
            E  T+DP+YYKWTQ +F  LYEKGLAY A+++VN   ELGT ++NEE+  +G S  GGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRMLRQWVLRITAFADQLLEGLDELDWPESVKQLQKNWIGKSSGASVNFATEHGAIE-  240
            V R+ +RQW+L+ITA+A++LLE+L+E+DWPES+K++Q+NWIGKS+GA+V F   +   + 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  -VFTTRPDTLIGVSFLALAPEHPLVDLLTSDEQKAVVAQYIKETQSKSERDRISEMKTKS  299
             VFTTRPDTL+G ++  LAPEH+LVD +T+ +Q   VA+Y +++  KS+  R    K K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  300  GVFTGSYAKHPVTHELIPIWIADYVLMGFGSGAVMGVPAHDERDLLFAEQFNLPVVSVLN  359
            GV TGSYA +PV    +P+WIADYVL ++G+GA+M+VPAHDERD  FA QFNL +++VL+
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  360  EEGVCINSCCE-GFH-----LDGLSGEEAKQYVINFLEENHLGAAKIAYKLRDWLFSRQR  413
               V   +  E G+H     LDGL    A   +++ LE + +G  +++Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  414  YWGEPIPIIHFEDGSCrplrddelpllppeIQDYRPEGVGQGPLAKVREWVQVFDTETQR  473
            YWGEPIPIIH EDG+  ++ + ELPL+ P  +D RP G G++PLA+V +W++V   +  +
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  474  AGKRETHTMPQWAGSCWYYLRFCDAHNSAAPWAKEKEQYWMPVDLYIGGAEHAVLHLLYA  533
             G+RET+TMPQWAGS WYYLR+ D+HN+      E  + W+PVD+Y+GGAEHAVLHLLYA
Sbjct  484  -GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  534  RFWHQVFYEAGIVSTPEPFKKLVNQGLVLATSYRIPGKGYIYPETAKEENGK-WVAPSGE  592
            RFWH+V+Y+ G+V+T EPF+KL NQG++L+TSYR +  + +  +     +G      +GE
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  593  ELDVRQEKMSKSKLNGVDPQILIDEFGADAVRMYAMFSGPLDKNKLWSNQGVAGCRRFLN  652
            EL+    KMSKS  N V+P+ +++++GAD++R+Y MF GPLD +  WS++G+ G R+FL+
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  653  RFYEMVSSDRVKEDNNFEGLSLAHKLVQRVTDAIEKLSLNTIPSSFMEFINDFVK----L  708
            R Y ++++  + E+N+     + +  V+ VT+ ++++ +NT  + +M F+N   K    +
Sbjct  663  RVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLF  722

Query  709  AVYPKSAVEMAVRALAPIAPHISEELW-VLLGNSPGVQKSGWPSVLPEYLEEQTVTIVVQ  767
            + Y+K+ V++    +AP+APH++EELW  L +++ ++    WPS     L E+ V IVVQ
Sbjct  723  SDYAKGFVQL----IAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQ  778

Query  768  VNGKLRARLDIMKDASKEEV--LALARESASKYLEGCEVKKAIFVPARLVNFVV  819
            ++GK++A+L + KD S+EE+  +ALA E     + G ++ K I VP +LVN+V+
Sbjct  779  IKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

611) leuS in NC_021893


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  683 bits (2582),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 414/834 (50%), Positives = 598/834 (72%), Gaps = 22/834 (2%)

Query  3    YDPGLIEEKWQKFWKNEQVFKAEEDETKTKYYVLDMFPYPSGAGLHVGHLIGYTATDIVA  62
            YD   IE KWQ FW +++ FK+  D +K K+Y LDMFPYPSGAGLHVGH  GYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RCKRAQGFSVLHPMGWDSFGLPAEQYAIRTGTHPRETTEKNIANFKKQLTAMGFSYDESR  122
            R KRAQG +VLHPMGWD+FGLPAEQYA+ TG +P E T  NIANFK+Q+ A+GFSYD  R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EFATSDPEYYKWTQKLFLILYEKGLAYMADMAVNYCPELGTVLSNEEI-ENGFSVDGGYP  181
            E  T+DP+YYKWTQ +F  LYEKGLAY A+++VN   ELGT ++NEE+  +G S  GGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRMLRQWVLRITAFADQLLEGLDELDWPESVKQLQKNWIGKSSGASVNFATEHGAIE-  240
            V R+ +RQW+L+ITA+A++LLE+L+E+DWPES+K++Q+NWIGKS+GA+V F   +   + 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  -VFTTRPDTLIGVSFLALAPEHPLVDLLTSDEQKAVVAQYIKETQSKSERDRISEMKTKS  299
             VFTTRPDTL+G ++  LAPEH+LVD +T+ +Q   VA+Y +++  KS+  R    K K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  300  GVFTGSYAKHPVTHELIPIWIADYVLMGFGSGAVMGVPAHDERDLLFAEQFNLPVVSVLN  359
            GV TGSYA +PV    +P+WIADYVL ++G+GA+M+VPAHDERD  FA QFNL +++VL+
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  360  EEGVCINSCCE-GFH-----LDGLSGEEAKQYVINFLEENHLGAAKIAYKLRDWLFSRQR  413
               V   +  E G+H     LDGL    A   +++ LE + +G  +++Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  414  YWGEPIPIIHFEDGSCrplrddelpllppeIQDYRPEGVGQGPLAKVREWVQVFDTETQR  473
            YWGEPIPIIH EDG+  ++ + ELPL+ P  +D RP G G++PLA+V +W++V   +  +
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  474  AGKRETHTMPQWAGSCWYYLRFCDAHNSAAPWAKEKEQYWMPVDLYIGGAEHAVLHLLYA  533
             G+RET+TMPQWAGS WYYLR+ D+HN+      E  + W+PVD+Y+GGAEHAVLHLLYA
Sbjct  484  -GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  534  RFWHQVFYEAGIVSTPEPFKKLVNQGLVLATSYRIPGKGYIYPETAKEENGK-WVAPSGE  592
            RFWH+V+Y+ G+V+T EPF+KL NQG++L+TSYR +  + +  +     +G      +GE
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  593  ELDVRQEKMSKSKLNGVDPQILIDEFGADAVRMYAMFSGPLDKNKLWSNQGVAGCRRFLN  652
            EL+    KMSKS  N V+P+ +++++GAD++R+Y MF GPLD +  WS++G+ G R+FL+
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  653  RFYEMVSSDRVKEDNNFEGLSLAHKLVQRVTDAIEKLSLNTIPSSFMEFINDFVK----L  708
            R Y ++++  + E+N+     + +  V+ VT+ ++++ +NT  + +M F+N   K    +
Sbjct  663  RVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLF  722

Query  709  AVYPKSAVEMAVRALAPIAPHISEELW-VLLGNSPGVQKSGWPSVLPEYLEEQTVTIVVQ  767
            + Y+K+ V++    +AP+APH++EELW  L +++ ++    WPS     L E+ V IVVQ
Sbjct  723  SDYAKGFVQL----IAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQ  778

Query  768  VNGKLRARLDIMKDASKEEV--LALARESASKYLEGCEVKKAIFVPARLVNFVV  819
            ++GK++A+L + KD S+EE+  +ALA E     + G ++ K I VP +LVN+V+
Sbjct  779  IKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

612) leuS in NC_021897


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  683 bits (2582),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 414/834 (50%), Positives = 598/834 (72%), Gaps = 22/834 (2%)

Query  3    YDPGLIEEKWQKFWKNEQVFKAEEDETKTKYYVLDMFPYPSGAGLHVGHLIGYTATDIVA  62
            YD   IE KWQ FW +++ FK+  D +K K+Y LDMFPYPSGAGLHVGH  GYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RCKRAQGFSVLHPMGWDSFGLPAEQYAIRTGTHPRETTEKNIANFKKQLTAMGFSYDESR  122
            R KRAQG +VLHPMGWD+FGLPAEQYA+ TG +P E T  NIANFK+Q+ A+GFSYD  R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EFATSDPEYYKWTQKLFLILYEKGLAYMADMAVNYCPELGTVLSNEEI-ENGFSVDGGYP  181
            E  T+DP+YYKWTQ +F  LYEKGLAY A+++VN   ELGT ++NEE+  +G S  GGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRMLRQWVLRITAFADQLLEGLDELDWPESVKQLQKNWIGKSSGASVNFATEHGAIE-  240
            V R+ +RQW+L+ITA+A++LLE+L+E+DWPES+K++Q+NWIGKS+GA+V F   +   + 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  -VFTTRPDTLIGVSFLALAPEHPLVDLLTSDEQKAVVAQYIKETQSKSERDRISEMKTKS  299
             VFTTRPDTL+G ++  LAPEH+LVD +T+ +Q   VA+Y +++  KS+  R    K K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  300  GVFTGSYAKHPVTHELIPIWIADYVLMGFGSGAVMGVPAHDERDLLFAEQFNLPVVSVLN  359
            GV TGSYA +PV    +P+WIADYVL ++G+GA+M+VPAHDERD  FA QFNL +++VL+
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  360  EEGVCINSCCE-GFH-----LDGLSGEEAKQYVINFLEENHLGAAKIAYKLRDWLFSRQR  413
               V   +  E G+H     LDGL    A   +++ LE + +G  +++Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  414  YWGEPIPIIHFEDGSCrplrddelpllppeIQDYRPEGVGQGPLAKVREWVQVFDTETQR  473
            YWGEPIPIIH EDG+  ++ + ELPL+ P  +D RP G G++PLA+V +W++V   +  +
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  474  AGKRETHTMPQWAGSCWYYLRFCDAHNSAAPWAKEKEQYWMPVDLYIGGAEHAVLHLLYA  533
             G+RET+TMPQWAGS WYYLR+ D+HN+      E  + W+PVD+Y+GGAEHAVLHLLYA
Sbjct  484  -GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  534  RFWHQVFYEAGIVSTPEPFKKLVNQGLVLATSYRIPGKGYIYPETAKEENGK-WVAPSGE  592
            RFWH+V+Y+ G+V+T EPF+KL NQG++L+TSYR +  + +  +     +G      +GE
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  593  ELDVRQEKMSKSKLNGVDPQILIDEFGADAVRMYAMFSGPLDKNKLWSNQGVAGCRRFLN  652
            EL+    KMSKS  N V+P+ +++++GAD++R+Y MF GPLD +  WS++G+ G R+FL+
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  653  RFYEMVSSDRVKEDNNFEGLSLAHKLVQRVTDAIEKLSLNTIPSSFMEFINDFVK----L  708
            R Y ++++  + E+N+     + +  V+ VT+ ++++ +NT  + +M F+N   K    +
Sbjct  663  RVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLF  722

Query  709  AVYPKSAVEMAVRALAPIAPHISEELW-VLLGNSPGVQKSGWPSVLPEYLEEQTVTIVVQ  767
            + Y+K+ V++    +AP+APH++EELW  L +++ ++    WPS     L E+ V IVVQ
Sbjct  723  SDYAKGFVQL----IAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQ  778

Query  768  VNGKLRARLDIMKDASKEEV--LALARESASKYLEGCEVKKAIFVPARLVNFVV  819
            ++GK++A+L + KD S+EE+  +ALA E     + G ++ K I VP +LVN+V+
Sbjct  779  IKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

613) leuS in NC_021887


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  683 bits (2582),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 414/834 (50%), Positives = 598/834 (72%), Gaps = 22/834 (2%)

Query  3    YDPGLIEEKWQKFWKNEQVFKAEEDETKTKYYVLDMFPYPSGAGLHVGHLIGYTATDIVA  62
            YD   IE KWQ FW +++ FK+  D +K K+Y LDMFPYPSGAGLHVGH  GYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RCKRAQGFSVLHPMGWDSFGLPAEQYAIRTGTHPRETTEKNIANFKKQLTAMGFSYDESR  122
            R KRAQG +VLHPMGWD+FGLPAEQYA+ TG +P E T  NIANFK+Q+ A+GFSYD  R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EFATSDPEYYKWTQKLFLILYEKGLAYMADMAVNYCPELGTVLSNEEI-ENGFSVDGGYP  181
            E  T+DP+YYKWTQ +F  LYEKGLAY A+++VN   ELGT ++NEE+  +G S  GGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRMLRQWVLRITAFADQLLEGLDELDWPESVKQLQKNWIGKSSGASVNFATEHGAIE-  240
            V R+ +RQW+L+ITA+A++LLE+L+E+DWPES+K++Q+NWIGKS+GA+V F   +   + 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  -VFTTRPDTLIGVSFLALAPEHPLVDLLTSDEQKAVVAQYIKETQSKSERDRISEMKTKS  299
             VFTTRPDTL+G ++  LAPEH+LVD +T+ +Q   VA+Y +++  KS+  R    K K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  300  GVFTGSYAKHPVTHELIPIWIADYVLMGFGSGAVMGVPAHDERDLLFAEQFNLPVVSVLN  359
            GV TGSYA +PV    +P+WIADYVL ++G+GA+M+VPAHDERD  FA QFNL +++VL+
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  360  EEGVCINSCCE-GFH-----LDGLSGEEAKQYVINFLEENHLGAAKIAYKLRDWLFSRQR  413
               V   +  E G+H     LDGL    A   +++ LE + +G  +++Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  414  YWGEPIPIIHFEDGSCrplrddelpllppeIQDYRPEGVGQGPLAKVREWVQVFDTETQR  473
            YWGEPIPIIH EDG+  ++ + ELPL+ P  +D RP G G++PLA+V +W++V   +  +
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  474  AGKRETHTMPQWAGSCWYYLRFCDAHNSAAPWAKEKEQYWMPVDLYIGGAEHAVLHLLYA  533
             G+RET+TMPQWAGS WYYLR+ D+HN+      E  + W+PVD+Y+GGAEHAVLHLLYA
Sbjct  484  -GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  534  RFWHQVFYEAGIVSTPEPFKKLVNQGLVLATSYRIPGKGYIYPETAKEENGK-WVAPSGE  592
            RFWH+V+Y+ G+V+T EPF+KL NQG++L+TSYR +  + +  +     +G      +GE
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  593  ELDVRQEKMSKSKLNGVDPQILIDEFGADAVRMYAMFSGPLDKNKLWSNQGVAGCRRFLN  652
            EL+    KMSKS  N V+P+ +++++GAD++R+Y MF GPLD +  WS++G+ G R+FL+
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  653  RFYEMVSSDRVKEDNNFEGLSLAHKLVQRVTDAIEKLSLNTIPSSFMEFINDFVK----L  708
            R Y ++++  + E+N+     + +  V+ VT+ ++++ +NT  + +M F+N   K    +
Sbjct  663  RVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLF  722

Query  709  AVYPKSAVEMAVRALAPIAPHISEELW-VLLGNSPGVQKSGWPSVLPEYLEEQTVTIVVQ  767
            + Y+K+ V++    +AP+APH++EELW  L +++ ++    WPS     L E+ V IVVQ
Sbjct  723  SDYAKGFVQL----IAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQ  778

Query  768  VNGKLRARLDIMKDASKEEV--LALARESASKYLEGCEVKKAIFVPARLVNFVV  819
            ++GK++A+L + KD S+EE+  +ALA E     + G ++ K I VP +LVN+V+
Sbjct  779  IKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

614) L2BLST_00212 in NC_020975


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  683 bits (2582),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 414/834 (50%), Positives = 598/834 (72%), Gaps = 22/834 (2%)

Query  3    YDPGLIEEKWQKFWKNEQVFKAEEDETKTKYYVLDMFPYPSGAGLHVGHLIGYTATDIVA  62
            YD   IE KWQ FW +++ FK+  D +K K+Y LDMFPYPSGAGLHVGH  GYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RCKRAQGFSVLHPMGWDSFGLPAEQYAIRTGTHPRETTEKNIANFKKQLTAMGFSYDESR  122
            R KRAQG +VLHPMGWD+FGLPAEQYA+ TG +P E T  NIANFK+Q+ A+GFSYD  R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EFATSDPEYYKWTQKLFLILYEKGLAYMADMAVNYCPELGTVLSNEEI-ENGFSVDGGYP  181
            E  T+DP+YYKWTQ +F  LYEKGLAY A+++VN   ELGT ++NEE+  +G S  GGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRMLRQWVLRITAFADQLLEGLDELDWPESVKQLQKNWIGKSSGASVNFATEHGAIE-  240
            V R+ +RQW+L+ITA+A++LLE+L+E+DWPES+K++Q+NWIGKS+GA+V F   +   + 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  -VFTTRPDTLIGVSFLALAPEHPLVDLLTSDEQKAVVAQYIKETQSKSERDRISEMKTKS  299
             VFTTRPDTL+G ++  LAPEH+LVD +T+ +Q   VA+Y +++  KS+  R    K K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  300  GVFTGSYAKHPVTHELIPIWIADYVLMGFGSGAVMGVPAHDERDLLFAEQFNLPVVSVLN  359
            GV TGSYA +PV    +P+WIADYVL ++G+GA+M+VPAHDERD  FA QFNL +++VL+
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  360  EEGVCINSCCE-GFH-----LDGLSGEEAKQYVINFLEENHLGAAKIAYKLRDWLFSRQR  413
               V   +  E G+H     LDGL    A   +++ LE + +G  +++Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  414  YWGEPIPIIHFEDGSCrplrddelpllppeIQDYRPEGVGQGPLAKVREWVQVFDTETQR  473
            YWGEPIPIIH EDG+  ++ + ELPL+ P  +D RP G G++PLA+V +W++V   +  +
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  474  AGKRETHTMPQWAGSCWYYLRFCDAHNSAAPWAKEKEQYWMPVDLYIGGAEHAVLHLLYA  533
             G+RET+TMPQWAGS WYYLR+ D+HN+      E  + W+PVD+Y+GGAEHAVLHLLYA
Sbjct  484  -GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  534  RFWHQVFYEAGIVSTPEPFKKLVNQGLVLATSYRIPGKGYIYPETAKEENGK-WVAPSGE  592
            RFWH+V+Y+ G+V+T EPF+KL NQG++L+TSYR +  + +  +     +G      +GE
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  593  ELDVRQEKMSKSKLNGVDPQILIDEFGADAVRMYAMFSGPLDKNKLWSNQGVAGCRRFLN  652
            EL+    KMSKS  N V+P+ +++++GAD++R+Y MF GPLD +  WS++G+ G R+FL+
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  653  RFYEMVSSDRVKEDNNFEGLSLAHKLVQRVTDAIEKLSLNTIPSSFMEFINDFVK----L  708
            R Y ++++  + E+N+     + +  V+ VT+ ++++ +NT  + +M F+N   K    +
Sbjct  663  RVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLF  722

Query  709  AVYPKSAVEMAVRALAPIAPHISEELW-VLLGNSPGVQKSGWPSVLPEYLEEQTVTIVVQ  767
            + Y+K+ V++    +AP+APH++EELW  L +++ ++    WPS     L E+ V IVVQ
Sbjct  723  SDYAKGFVQL----IAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQ  778

Query  768  VNGKLRARLDIMKDASKEEV--LALARESASKYLEGCEVKKAIFVPARLVNFVV  819
            ++GK++A+L + KD S+EE+  +ALA E     + G ++ K I VP +LVN+V+
Sbjct  779  IKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

615) L11322_00213 in NC_020972


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  683 bits (2582),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 414/834 (50%), Positives = 598/834 (72%), Gaps = 22/834 (2%)

Query  3    YDPGLIEEKWQKFWKNEQVFKAEEDETKTKYYVLDMFPYPSGAGLHVGHLIGYTATDIVA  62
            YD   IE KWQ FW +++ FK+  D +K K+Y LDMFPYPSGAGLHVGH  GYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RCKRAQGFSVLHPMGWDSFGLPAEQYAIRTGTHPRETTEKNIANFKKQLTAMGFSYDESR  122
            R KRAQG +VLHPMGWD+FGLPAEQYA+ TG +P E T  NIANFK+Q+ A+GFSYD  R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EFATSDPEYYKWTQKLFLILYEKGLAYMADMAVNYCPELGTVLSNEEI-ENGFSVDGGYP  181
            E  T+DP+YYKWTQ +F  LYEKGLAY A+++VN   ELGT ++NEE+  +G S  GGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRMLRQWVLRITAFADQLLEGLDELDWPESVKQLQKNWIGKSSGASVNFATEHGAIE-  240
            V R+ +RQW+L+ITA+A++LLE+L+E+DWPES+K++Q+NWIGKS+GA+V F   +   + 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  -VFTTRPDTLIGVSFLALAPEHPLVDLLTSDEQKAVVAQYIKETQSKSERDRISEMKTKS  299
             VFTTRPDTL+G ++  LAPEH+LVD +T+ +Q   VA+Y +++  KS+  R    K K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  300  GVFTGSYAKHPVTHELIPIWIADYVLMGFGSGAVMGVPAHDERDLLFAEQFNLPVVSVLN  359
            GV TGSYA +PV    +P+WIADYVL ++G+GA+M+VPAHDERD  FA QFNL +++VL+
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  360  EEGVCINSCCE-GFH-----LDGLSGEEAKQYVINFLEENHLGAAKIAYKLRDWLFSRQR  413
               V   +  E G+H     LDGL    A   +++ LE + +G  +++Y+LRDWLFSRQR
Sbjct  364  GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  414  YWGEPIPIIHFEDGSCrplrddelpllppeIQDYRPEGVGQGPLAKVREWVQVFDTETQR  473
            YWGEPIPIIH EDG+  ++ + ELPL+ P  +D RP G G++PLA+V +W++V   +  +
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK  483

Query  474  AGKRETHTMPQWAGSCWYYLRFCDAHNSAAPWAKEKEQYWMPVDLYIGGAEHAVLHLLYA  533
             G+RET+TMPQWAGS WYYLR+ D+HN+      E  + W+PVD+Y+GGAEHAVLHLLYA
Sbjct  484  -GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYA  542

Query  534  RFWHQVFYEAGIVSTPEPFKKLVNQGLVLATSYRIPGKGYIYPETAKEENGK-WVAPSGE  592
            RFWH+V+Y+ G+V+T EPF+KL NQG++L+TSYR +  + +  +     +G      +GE
Sbjct  543  RFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGE  602

Query  593  ELDVRQEKMSKSKLNGVDPQILIDEFGADAVRMYAMFSGPLDKNKLWSNQGVAGCRRFLN  652
            EL+    KMSKS  N V+P+ +++++GAD++R+Y MF GPLD +  WS++G+ G R+FL+
Sbjct  603  ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLD  662

Query  653  RFYEMVSSDRVKEDNNFEGLSLAHKLVQRVTDAIEKLSLNTIPSSFMEFINDFVK----L  708
            R Y ++++  + E+N+     + +  V+ VT+ ++++ +NT  + +M F+N   K    +
Sbjct  663  RVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLF  722

Query  709  AVYPKSAVEMAVRALAPIAPHISEELW-VLLGNSPGVQKSGWPSVLPEYLEEQTVTIVVQ  767
            + Y+K+ V++    +AP+APH++EELW  L +++ ++    WPS     L E+ V IVVQ
Sbjct  723  SDYAKGFVQL----IAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQ  778

Query  768  VNGKLRARLDIMKDASKEEV--LALARESASKYLEGCEVKKAIFVPARLVNFVV  819
            ++GK++A+L + KD S+EE+  +ALA E     + G ++ K I VP +LVN+V+
Sbjct  779  IKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

616) leuS in NC_018626


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  681 bits (2574),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 407/836 (49%), Positives = 595/836 (72%), Gaps = 25/836 (2%)

Query  3    YDPSLIEKKWQQFWKEHKSFKADETADKPKYYVLDMFPYPSGAGLHVGHLIGYTATDIVA  62
            YD + IE KWQ FW ++ +FK++  A KPK+Y LDMFPYPSGAGLHVGH  GYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRAKGFSVLHPMGWDSFGLPAEQYAVRTGTHPRETTKKNIENFRKQLSAMGFSYDEGR  122
            R+KRA+G +VLHPMGWD+FGLPAEQYA+ TG +P E T  NI NF++Q++A+GFSYD +R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EFATSDPDYYRWTQKLFLFLYEKGLAYMADMAVNYCEELGTVLANEEV-ENGLSVEGGYP  181
            E  T+DP+YY+WTQ +F  LYEKGLAY A+++VN  EELGT +ANEEV  +G S  GGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRMLRQWILRITAYSDQLLQGLEDLDWPENVKQLQRNWIGKSEGALVRFEV-DNGNFL  240
            V R+ +RQW+L+ITAY+++LL++LE++DWPE++K++QRNWIGKS GA V F V D ++ +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  SVFTTRPDTLCGVSFLVMAPEHPEINHLVSEEQRSAVENYIRCVQSKSERERISETKVKS  300
            +VFTTRPDTL G ++ V+APEH+ ++ + + +Q  AV +Y R    KS+  R   +K K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  301  GVFIGAYAKHPITGALLPIWVSDYVIMGYGSGVVMGVPAHDERDREFANAFALPISEVLD  360
            GV  G+YA +P+ G  +P+W++DYV+ +YG+G +M+VPAHDERD+EFA+ F L I  VL+
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  361  DNG--------QCIHSNHRDFLLNGLRGKEARDYVIAYLQKKNLGEAKVVYKLRDWLFSR  412
            +          + +H N  DF L+GL    A   ++  L+   +G+ +V Y+LRDWLFSR
Sbjct  364  GGNVEEAAFTEDGLHIN-SDF-LDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSR  421

Query  413  QRYWGEPIPIIHFEDGTCRpleddelpvlppeIQDYRPKGFGQGPLANVKEWVEIHDVKT  472
            QRYWGEPIPIIH EDGT  ++ + ELP++ P  +D RP G G++PLANV +W+E+     
Sbjct  422  QRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTR-ED  480

Query  473  NRKGRRETHTMPQWAGSCWYYLRFCDAHNSQAPWSNENERYWMPVDLYIGGAEHAVLHLL  532
              KGRRET+TMPQWAGS WYYLR+ D+HN++    +E  + W+PVD+Y+GGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  533  YSRFWHRVFYEAGLVSTPEPFKKLINQGLVLATSYRILGKGYVHPEDVREDNGK-WTTAS  591
            Y+RFWH+V+Y+ G+V+T EPF+KL+NQG++L+TSYR    + V  + V   +G      +
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  592  GEELEVRQEKMSKSKLNGVDPQTLIDEFGADALRMYAMFSGPLDKNKLWCNHGVSGCRRF  651
            GEELE    KMSKS  N V+P+ +++++GAD+LR+Y MF GPLD +  W ++G+ G R+F
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  652  LNRFYELVTSSAVEDVDDPKGMALAHRLVHRVGEDIEKMSLNTIPSSFMEFINEFTK---  708
            L+R Y L+T+  + + +      + +  V  V E++++M +NT  + +M F+N   K   
Sbjct  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  709  -LDTYPKSALAMVVRALAPIAPHISEELWTIL-GYAPGIDKAGWPEVDPKYLEDASVTFV  766
             +  Y+K+ + ++    AP+APH++EELW  L + + +I    WP  D   L +  V +V
Sbjct  721  LFSDYAKGFVQLI----APFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  767  IQVNGKLRARLDIDKNTSQEDI--LSAARESVAKYLEDKEIKKEVFVPNRLVNFVL  820
            +Q++GK++A+L + K+ S+E++  ++ A E V   + +K+I K + VPN+LVN+V+
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

617) leuS in NC_011374


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  680 bits (2572),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 407/829 (50%), Positives = 576/829 (70%), Gaps = 58/829 (6%)

Query  2    YNHNKIEKKWQKYWLDNKTFKFVDNPNNPKKFYVLDMFPYPSGKGLHVGHPKGYTATDVI  61
            Y+H  IE KWQ +W DN TFK   ++++PK FY LDMFPYPSG GLHVGHP GYTATD++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPK-FYALDMFPYPSGAGLHVGHPEGYTATDIL  62

Query  62   SRFKRLNGYDVLHPIGWDAFGLPAEQYALETNNHPHTFTQQNIKIFRKQLQMIGFDFDYD  121
            SRFKR +G +VLHP+GWDAFGLPAEQYA++T N+P  FT +NI  F++Q++ +GF +D D
Sbjct  63   SRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWD  122

Query  122  KEVDTTDPQFYQWTQWIFVQLYKHNLAEIQDIDVNWCENLGTVLSNEEVVLNDKNERVSE  181
            +EV+TTDP++Y+WTQWIF +LY   LA   ++ VNW E+LGT ++NEEV+     +  SE
Sbjct  123  REVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVL----PDGTSE  178

Query  182  RGGHPVVRKPMKQWVLKIVDYADKLLDGLNEVEFSESLKSLQRNWIGKSIGTNVQFKIKD  241
            RGG PVVRKPM+QW+LKI  YA++LL++L+EV+ +ES+K +QRNWIGKS G+NV FK+KD
Sbjct  179  RGGYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKD  238

Query  242  SHLALDVFTTRIDTIYGAQYLVVAPEHPILKSIVSEQQASVVQAYVDQTKKISDLDRIA-  300
            ++  + VFTTR DT++GA Y V+APEH+++ +I + +QA  V  Y  Q+   SDL R   
Sbjct  239  TDKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDL  298

Query  301  DTNKTGVFSGTYAINPINQEIIPIWVSDYVLMNFATGAVMGVPAHDERDYAFAKKYDLPI  360
              +KTGV +G+YAINP+N   +P+W++DYVL +++TGA+M+VPAHDERD  FAK+++L I
Sbjct  299  AKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDI  358

Query  361  KSVIDTK--QSLPYTGDGLHINSPMINGLNIEQSQNILNDYLVKNHLAKRVVNYKLRNWI  418
             +V++    +  ++T DGLHINS  ++GL+   +   + + L  + +++  V Y+LR+W+
Sbjct  359  IPVLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWL  418

Query  419  FSRQRYWGEPFPVL-FDENNQIKIIE-DLPVLLPNLDEFKPSKTGESPLANAQEWLYVEI  476
            FSRQRYWGEP+P++  ++     + E +LP++LP   +++PS TGESPLAN  +WL V  
Sbjct  419  FSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTR  478

Query  477  -DGKKYRRETNTMPQWAGSSWYFLAYILKNEDGSYTPLNSEEAKKRFAKWLPVDVYIGGQ  535
             DG K RRETNTMPQWAGSSWY+L YI  ++      L  EE  K+   WLPVD+Y+GG 
Sbjct  479  EDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEK---LADEELLKQ---WLPVDIYVGGA  532

Query  536  EHAVLHLLYARFWHRFLYDIGVVPTKEPFYKVINQGMILG--------------------  575
            EHAVLHLLYARFWH+ LYD+GVVPTKEPF K++NQGMILG                    
Sbjct  533  EHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRD  592

Query  576  -------------ENNEKMSKSKGNVINPDDIIASHGADTLRIYEMFMGPLTASLPWSPD  622
                         +   KMSKS  NV+NPDD++   GADTLR+YEMFMGPL AS++WS +
Sbjct  593  GSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEE  652

Query  623  GLDAMRKWLDRVYRLYHNLSELEVVEDVNKLNEEIIITYHTLIKNYTKAINEQAFNIAIS  682
            GL++ RK LDRVYRL   ++  E+ E+ +   + +   Y+  +K  T  +++  FN AI+
Sbjct  653  GLEGSRKFLDRVYRL---ITTKEITEENSGALDKV---YNETVKAVTEQVDQMKFNTAIA  706

Query  683  EMMVFVNVLYKNKVINYKLLDNFLILLSCFAPHLAEELYS--LNHSESVCLQKMPIYDEQ  740
            ++MVFVN   K+  +       F+ L++ FAPHL+EEL       +ES+     P YDE 
Sbjct  707  QLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDES  766

Query  741  KIIAQNVTIPIQINGKLKHTINVLRDTNAEQLINLALACEQVKQAIGDQ  789
            K++ ++V I +QI+GK+K  + V +D + E+L ++ALA E+V+  I+++
Sbjct  767  KLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGK  815

618) leuS in NC_003361


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  679 bits (2568),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 409/832 (50%), Positives = 599/832 (72%), Gaps = 17/832 (2%)

Query  3    YDPSLIEKKWQEFWKEHKSFEADEASDKPKYYVLDMFPYPSGAGLHVGHLIGYTATDIVA  62
            YD + IE KWQ FW ++ +F ++  + KPK+Y LDMFPYPSGAGLHVGH  GYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRAKGYAVLHPMGWDSFGLPAEQYAVRTGTHPRETTQKNIENFRKQLSAMGFSYDEGR  122
            R+KRA+G  VLHPMGWD+FGLPAEQYA+ TG +P E T  NI NF++Q++A+GFSYD +R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EFATSDPDYYRWTQKLFLFLYEKGLAYMADMAVNYCPELGTVLSNEEV-ENGLSVEGGYP  181
            E  T+DP+YY+WTQ +F  LYEKGLAY A+++VN   ELGT ++NEEV  +G S  GGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRMLRQWILRITAYSDQLLEGLEDLDWPENVKQLQRNWIGKSEGALVRFEVNN-ERFL  240
            V R+ +RQW+L+ITAY+++LLE+LE++DWPE++K++QRNWIGKS GA V F V++ ++ +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  EVFTTRPDTIGGVSFLVVAPEHPEVNRLISENQREAVESYIRAAQSKSERDRISETKVKT  300
             VFTTRPDT+ G ++ V+APEH+ V+ + + +Q EAV  Y R A  KS+  R   +K KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  301  GVFTGTYAKHPVTGADIPIWISDYVILGYGSGVVMGVPAHDERDREFAEAFSLPIYEVLD  360
            GV TG+YA +PV G ++P+WI+DYV+ +YG+G +M+VPAHDERD+EFA  F+L I  VL+
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  361  K---DECCIHSN----HGDFLLDGLAGQEARDYVIAYLQKKNLGEAKVAYKLRDWLFSRQ  413
                +E  +  +    ++DF LDGL    A   ++  L+   +G+ +V+Y+LRDWLFSRQ
Sbjct  364  GGNVEEAAFTEDGLHINSDF-LDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQ  422

Query  414  RYWGEPIPIIHFEDGTCRpleddelpllppeIQDYRPEGFGQGPLAKVKEWVDIHDTKTN  473
            RYWGEPIPIIH EDGT  ++ + ELPL+ P  +D RP G G++PLA+V +W+++      
Sbjct  423  RYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV-TREDG  481

Query  474  RRGRRETHTMPQWAGSCWYYLRFCDAHNSQAPWSNENERYWMPVDLYIGGAEHAVLHLLY  533
             +GRRET+TMPQWAGS WYYLR+ D+HN++    +E  + W+PVD+Y+GGAEHAVLHLLY
Sbjct  482  VKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLY  541

Query  534  SRFWHRVFYEAGMVSTAEPFKKLINQGLVLATSYRIPGKGYVYPED-AREDNGVWMSASG  592
            +RFWH+V+Y+ G+V+T EPF+KL+NQG++L+TSYR +  + V  +   + D +     +G
Sbjct  542  ARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETG  601

Query  593  EELEVRQEKMSKSKLNGVDPQILIDEFGADALRMYAMFSGPLDKNKLWSNQGVSGCRRFL  652
            EELE    KMSKS  N V+P+ +++++GAD+LR+Y MF GPLD +  WS++G+ G R+FL
Sbjct  602  EELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFL  661

Query  653  NRFYEMATSASVQDVDDPKGMALAHRLVHRVGEDIEKMSLNTIPSSFMEFINEFVKLD-I  711
            +R Y + T+  + + +      + +  V  V E++++M +NT  + +M F+N   K D +
Sbjct  662  DRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKL  721

Query  712  YPRSALAMVVQALAPIAPHISEELWTVL-GYAPGIDAAGWPKVDPKYLEDTSVTFVIQVN  770
            ++  A +  VQ +AP+APH++EELW  L + + +I    WP  D   L +  V +V+Q++
Sbjct  722  FSDYAKGF-VQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK  780

Query  771  GKLRARLDMDKATSKEDV--LSLAREAVAKYLEGKEVKKEVFVPNRLVNFVL  820
            GK++A+L + K  S+E++  ++LA E V   + GK++ K + VPN+LVN+V+
Sbjct  781  GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

619) leuS in NC_004552


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  679 bits (2569),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 405/835 (49%), Positives = 595/835 (72%), Gaps = 23/835 (2%)

Query  3    YDPSLIEKKWQQFWKEHKSFKADETADKPKYYVLDMFPYPSGAGLHVGHLIGYTATDIVA  62
            YD + IE KWQ FW ++ +FK++  A KPK+Y LDMFPYPSGAGLHVGH  GYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRAKGFSVLHPMGWDSFGLPAEQYAVRTGTHPRETTKKNIENFRKQLSAMGFSYDEAR  122
            R+KRA+G +VLHPMGWD+FGLPAEQYA+ TG +P E T  NI NF++Q++A+GFSYD  R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EFATSDPEYYRWTQKLFLFLYEKGLAYMADMAVNYCEELGTVLANEEV-ENGLSIEGGYP  181
            E  T+DP+YY+WTQ +F  LYEKGLAY A+++VN  EELGT +ANEEV  +G S  GGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRMLRQWILRITAYADQLLQGLEDLDWPENVKQLQRNWIGKSEGALLRF-VVDKDKCL  240
            V R+ +RQW+L+ITAYA++LL++LE++DWPE++K++QRNWIGKS GA + F V D DK +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  EVFTTRPDTLCGVSFLVMAPEHPEIQQLVSEEQRSAVESYIRCAQSKSERERISETKVKS  300
             VFTTRPDTL G ++ V+APEH+ ++ + + +Q  AV  Y R A  KS+  R   +K K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  301  GVFTGAYAKHAITGAALPIWVSDYVIMGYGSGVVMGVPAHDERDREFANAFALPIDEVLD  360
            GV TG+YA +++ G  +P+W++DYV+ +YG+G +M+VPAHDERD+EFA+ F L I  VL+
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  361  E---NEHCINSN----HGDFLLNGLQGKEASDYVIAYLQKRNLGEAKVMYKLHDWLFSRQ  413
                +E  +  +    ++DF L+GL+   A   ++  L+   +G+ +V Y+L+DWLFSRQ
Sbjct  364  GGNVEEAAFTEDGLHINSDF-LDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQ  422

Query  414  RYWGEPIPIIHFEDGTCRpleddelpllppeIQDYRPKGFGQGPLAKVKEWVDIHDVKTQ  473
            RYWGEPIPIIH EDGT  ++ + ELPL+ P  +D RP G G++PLA+V +W+++      
Sbjct  423  RYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGV  482

Query  474  RPGRRETHTMPQWAGSCWYYLRFCDAHNSQAPWSHENERYWMPVDLYIGGAEHAVLHLLY  533
            + GRRET+TMPQWAGS WYYLR+ D+HN++    +E  + W+PVD+Y+GGAEHAVLHLLY
Sbjct  483  K-GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLY  541

Query  534  SRFWHRVFYEAGLVSTPEPFKKLINQGLVLATSYRIPGKGYVHPEDAREDNGK-WTTASG  592
            +RFWH+V+Y+ G+V+T EPF+KL+NQG++L+TSYR +  + V  +     +G      +G
Sbjct  542  ARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETG  601

Query  593  EELEVRQEKMSKSKLNGVDPQILIDEFGADALRMYAMFSGPLDKNKLWCNQGVSGCRRFL  652
            EELE    KMSKS  N V+P+ +++++GAD+LR+Y MF GPLD +  W ++G+ G R+FL
Sbjct  602  EELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFL  661

Query  653  NRFYELATSSAVQDIDDPKGMALAHRLVHKVGEDIEKMSLNTIPSSFMEFINEFAK----  708
            +R Y L T+  + + +      + +  V  V E++++M +NT  + +M F+N   K    
Sbjct  662  DRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKL  721

Query  709  LDTYSKSALSMVVRALAPIAPHISEELWTVL-GYAPGIDNAGWPEVDPKYLEDTSVTFVI  767
            +  Y+K+ + ++    AP+APH++EELW  L + + +I    WP  D   L +  V +V+
Sbjct  722  FSDYAKGFVQLI----APFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVV  777

Query  768  QVNGKLRARLDMDKNTSQEDI--LSAARESVAKYLEDKEIKKEVFVPNRLVNFVL  820
            Q++GK++A+L + K+ S+E++  ++ A E V   + +K+I K + VPN+LVN+V+
Sbjct  778  QIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

620) Isop_2280 in NC_014962


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  679 bits (2569),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 466/952 (49%), Positives = 624/952 (66%), Gaps = 127/952 (13%)

Query  1    MPAYHFQRIESKWQAYWRQHRTFRAPDLPARPKLYVLDMFPYPSGDGLHVGHPEGYTATD  60
            M  Y+   IE+KWQA+W +++TF++   +++PK+Y LDMFPYPSG GLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   IYARYKRMRGYDVLHPMGWDAFGLPAEQHAIKTGTHPGAKTQANIATFKRQIESLGFSYD  120
            I +R+KR +G +VLHPMGWDAFGLPAEQ A+ TG +P+  T  NIA FKRQI++LGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WDREIDTTDPNYYRWTQWIFLQLFDTWYDPDFEWTDPQGRSRRGKGRPIAELPIPPGIDP  180
            WDRE++TTDPNYY+WTQWIF +L                                     
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKL-------------------------------------  143

Query  181  YDYRDSKRLAYRAEVPVNWCPELGTVLANEEVV-DGKSEVGGFPVIRLPLKQWMLRITAY  239
            Y+    K LAY AEVPVNW  ELGT +ANEEV+ DG SE GG+PV+R P++QWML+ITAY
Sbjct  144  YE----KGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAY  199

Query  240  ADRLLEDLDLVDWPEPIKDMQRNWIGRSEGAEVDFPLAYPDFDFAAWSQARAAIGFPPPQ  299
            A+RLLEDL+ VDWPE+IKDMQRNWIG+S GA+V F +   D DF+               
Sbjct  200  AERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFT---------------  244

Query  300  AVGHQVIRIYTTRPDTLFGATYMVLAPEHPLVDRITTPEQrdavaayrraaaaKSDLDRT  359
                    ++TTRPDTLFGATY VLAPEH+LVD ITT++Q +AVA Y+R A+ KSDL RT
Sbjct  245  --------VFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLART  296

Query  360  DLAKTKTGVATGAFAVNPVTGQLIPVWIADYVLMGYGTGAIMAVPGHDERDFEFARAFGL  419
            DLAK KTGV TG++A+NPV G+ +PVWIADYVL +YGTGAIMAVP+HDERD EFA+ F L
Sbjct  297  DLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNL  356

Query  420  PIRRVVaaaldqadqpldqaETAYAVSVNSANAELKLDGLPSAQAKVEITNWLTSKGFGR  479
             I  V+        +  +  E+A++      N+++ LDGL  A A   + +WL + G G 
Sbjct  357  DIIPVL--------EGGNVEEAAFTEDGLHINSDF-LDGLDKASAIAKMVEWLEAEGVGN  407

Query  480  KAVNTKLRDWLFSRQRYWGEPFPILLDDQDRAHPVPVEQLPVRLPELADFKPTGKPEPPL  539
              V  +LRDWLFSRQRYWGEP+PI+  +++ + +VP  +LP+ LP   D++P+G  E+PL
Sbjct  408  ENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPL  467

Query  540  SKAVAWV-----NEIPGFRRETNTMPQWAGSCWYYLRYIDPRNDQAPWDPAKERAWMPVD  594
            ++   W+     + + G RRETNTMPQWAGS WYYLRYIDP+N +   D    + W+PVD
Sbjct  468  ANVTDWLEVTREDGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVD  526

Query  595  LYIGGAEHAVLHLLYSRFWHKVLFDRGYVSHPEPFQRLVNQGMILGEIEYHAYQTEDGRL  654
            +Y+GGAEHAVLHLLY+RFWHKVL+D G V+  EPFQ+L NQGMILG     +Y+   G L
Sbjct  527  IYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGT----SYRDSRGAL  582

Query  655  VSVDHVIDTPQGPTLQSTPPDAQPIPVRLLKLDPAAVVKTGSGFVMADHPEIKVEGRASK  714
            V+ D                                V K +++F   +  E  +E  ++K
Sbjct  583  VATDK-------------------------------VEKRDGSFFHVETGE-ELEQAPAK  610

Query  715  MSKSRGNVINPDGVVAEYGADSLRLYEMFMGPLEATKPWSMKGVEGVYRFLNRAWRMIVD  774
            MSKS  NV+NPD+VV +YGAD+LR+YEMFMGPL+A+ +WS  G+EG  +FL+R  R+I  
Sbjct  611  MSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLIT-  669

Query  775  EEAETPRLHPKVVDIEPSAELVRLTARTIAAVTEDLEGLRFNTAISRLMEFVNAVAPLEA  834
                      K +  E S+ L ++   T+ AVTE+++ ++FNTAI++LM FVNA    + 
Sbjct  670  ---------TKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  835  RPKAVLETFTLLLAPMAPHIAEELWEVL-GHATSLAYHPWPTYDPNDLKEDRIEIPVQIN  893
                    F  L+AP APH++EELW+ L + + S++Y PWP+YD + L E+ +EI VQI+
Sbjct  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK  780

Query  894  GKLRGKVVVDAQaepaaieeaaraepriaeLLRGKTIRKAIVAKGKLVNFVV  945
            GK+++K+VV  +     ++E A A+ ++   + GK I K I    KLVN+V+
Sbjct  781  GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

621) Aaci_0425 in NC_013205


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  678 bits (2563),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 404/835 (49%), Positives = 571/835 (69%), Gaps = 41/835 (4%)

Query  3    YRPQQIEQKWKARWREQNAHRADGKSGKPKYYCLDMFPYPSGSGLHVGHWRGYTISDVWS  62
            Y    IE KW+A W ++++ +++  ++KPK+Y LDMFPYPSG+GLHVGH  GYT +D+ S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKKLHGYEILHPMGWDAFGLPAENYAIQNGIHPRIATEQNIANFKRQLEEIGAMYDWDR  122
            R+K+ +G ++LHPMGWDAFGLPAE+YA++ G +P   T +NIANFKRQ++ +G  YDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVNTTDPSFYKWTQYFFVKMFERGLAYRKKMPINWCPSCKTGLANEEVV-DGCCERCGAP  181
            EVNTTDP++YKWTQ +F K++E+GLAY   +P+NW     T++ANEEV+ DG  ER G P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VTRREMEQWMLKITDYADRLLNDLDKLDWPEHVKRMQRAWIGRSEGARIRFRLVDHDGEI  241
            V R+ M QWMLKIT YA+RLL+DL+ +DWPE +K MQR WIG+S GA + F++ D D ++
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  EVFSTRPDTIYGATYMVLAPEHPLVSQITAPDRKAEVEAYVEQALRKSNVERQVVDKTKT  301
             VF+TRPDT++GATY VLAPEH+LV  IT++D+   V  Y  QA  KS++ R  + K KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYVQHPLLDKRLPVWIADYVLMDYGTGAIMAVPAHDDRDFEFAEQFGLEIVEVVR  361
            GV TG+Y  +P+ +K +PVWIADYVL  YGTGAIMAVPAHD+RD EFA QF L+I+ V+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  PRDGASELPFTGDGVLVNSGPLDGLPVEEAKKRAIELMAEKGQAEPAVSYRLRDWVFARQ  421
              +   E +FT DG+ +NS+ LDGL    A  + +E +   G ++  V+YRLRDW+F+RQ
Sbjct  364  G-GNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQ  422

Query  422  RYWGEPIPIVYCQVCGTVPVPEDQLPVLLPDVERYEPTGTGESPLAAIESFVNTTCPKCG  481
            RYWGEPIPI+  +   + +VPE +LP++LP      P+GTGESPLA +   ++ T    G
Sbjct  423  RYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED-G  481

Query  482  GPAKRETDTMPQWAGSCWYFLRYADPHNDKEPFSREAVNYWLPVDMYIGGVEHAVLHLLY  541
              ++RET+TMPQWAGS WY+LRY DPHN       E ++ WLPVD+Y+GG EHAVLHLLY
Sbjct  482  VKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLY  541

Query  542  SRFYVKFIYDLGLIDFDEPFQRLFTQGMI-------------------------------  570
            +RF  K +YDLG++   EPFQ+LF QGMI                               
Sbjct  542  ARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETG  601

Query  571  ---TLNGAKMSKSKGNVVNPDDIIARYGVDALRMYEMFVGPPEDDAEWSTNGLEGVARFL  627
                   AKMSKS  NVVNPDD++ +YG D+LR+YEMF+GP +    WS +GLEG  +FL
Sbjct  602  EELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFL  661

Query  628  ARVYRLYAQQVDKLVPERPSLTKLRHRFVATLTERMESFRLNTAVSAFMEYVNNLQQEAK  687
             RVYRL + + +    +  +L K+ +  V ++TE+++  ++NTA++ +M +VN  ++E K
Sbjct  662  DRVYRLITTK-EITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  688  DGLDRATLETLAIAIAPFTPHLGEELWEMLGHTDSVFE-QSWPTYDKAWLRDDEVEIAVQ  746
              L       +   IAPF+PHLGEELW+ L  ++  +   +WP+YD + L +++VEI VQ
Sbjct  721  --LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQ  778

Query  747  VNGRVRGRLTLPADVSAEDAIARAKALPDIREWIEGKQVVKEVFVPGRIVNLVVK  801
            ++G+V+++L ++ D+S E+    A A   ++  I GK+++K + VP ++VN+V+K
Sbjct  779  IKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

622) leuS in NC_017167


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  675 bits (2553),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 408/835 (49%), Positives = 571/835 (69%), Gaps = 41/835 (4%)

Query  3    YRPQEIEKKWKARWREQNAHRADGKSGKPKYYCLDMFPYPSGSGLHVGHWRGYTISDVWS  62
            Y    IE KW+A W ++++ +++  ++KPK+Y LDMFPYPSG+GLHVGH  GYT +D+ S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKKLHGYEILHPMGWDAFGLPAENYAIQNGIHPRIATERNIANFKRQLEEIGAMYDWDR  122
            R+K+ +G ++LHPMGWDAFGLPAE+YA++ G +P   T  NIANFKRQ++ +G  YDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVNTTDPSFYKWTQYFFVKMFERGLAYRKKMPINWCPSCKTGLANEEVV-DGCCERCGAP  181
            EVNTTDP++YKWTQ +F K++E+GLAY   +P+NW     T++ANEEV+ DG  ER G P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VTRREMEQWMLKITDYADRLLNDLDKLDWPEHVKRMQRAWIGRSEGARIRFRLVDHDGEI  241
            V R+ M QWMLKIT YA+RLL+DL+ +DWPE +K MQR WIG+S GA + F++ D D ++
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  EVFSTRPDTIYGATYMVLAPEHPLVPQITAPDRKAEVEAYIEQALRKSNVERQVVDKTKT  301
             VF+TRPDT++GATY VLAPEH+LV  IT++D+   V  Y  QA  KS++ R  + K KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVFTGAYVQHPLLDKRLPVWIADYVLMDYGTGAIMAVPAHDDRDFEFAEQFGLEIVEVVR  361
            GV TG+Y  +P+ +K +PVWIADYVL  YGTGAIMAVPAHD+RD EFA QF L+I+ V+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  362  PLDGVTELPFTGDGVLVNSGPLDGLPVEEAKKRAIELMAAKGQAEPAVSYRLRDWVFARQ  421
              + V E +FT DG+ +NS+ LDGL    A  + +E + A G ++  V+YRLRDW+F+RQ
Sbjct  364  G-GNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQ  422

Query  422  RYWGEPIPIVYCEVCGTVPVPEDQLPVLLPDVERYEPTGTGESPLAAIESFVNTTCPKCG  481
            RYWGEPIPI+  E   + +VPE +LP++LP      P+GTGESPLA +   ++ T    G
Sbjct  423  RYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED-G  481

Query  482  GPAKRETDTMPQWAGSCWYFLRYADPHNDQEPFSREAVNYWLPVDMYIGGVEHAVLHLLY  541
              ++RET+TMPQWAGS WY+LRY DPHN +     E ++ WLPVD+Y+GG EHAVLHLLY
Sbjct  482  VKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLY  541

Query  542  SRFYVKFIYDLGLIDFDEPFQRLFTQGMI-------------------------------  570
            +RF  K +YDLG++   EPFQ+LF QGMI                               
Sbjct  542  ARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETG  601

Query  571  ---TLNGAKMSKSKGNVVNPDDIIARHGVDALRMYEMFVGPPEEDAEWSTNGLEGVARFL  627
                   AKMSKS  NVVNPDD++ + G D+LR+YEMF+GP +    WS +GLEG  +FL
Sbjct  602  EELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFL  661

Query  628  ARVYRLYAQHVDKLVPERPSLTKLRHRFVATLTERMESFRLNTAVSAFMEYVNNLQQEAK  687
             RVYRL +   +    +  +L K+ +  V ++TE+++  ++NTA++ +M +VN  ++E K
Sbjct  662  DRVYRLITTK-EITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  688  EGLDRATLETLAVAIAPFTPHLGEELWEMLGHTDSVFE-QSWPTYDEAWLRDDEVEIAVQ  746
              L       +   IAPF+PHLGEELW+ L  ++  +   +WP+YDE+ L +++VEI VQ
Sbjct  721  --LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQ  778

Query  747  VNGRVRGRLTLPADTSAEEAVARAKALPDIREWIEGKQVVKEVYVPGRIVNLVVK  801
            ++G+V+++L ++ D S EE    A A   ++  I GK+++K + VP ++VN+V+K
Sbjct  779  IKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

623) A11Q_2231 in NC_020813


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  675 bits (2552),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 404/833 (49%), Positives = 575/833 (70%), Gaps = 49/833 (5%)

Query  3    HTEIESKWQKVWADKQAYKSENNSTRPKYYALDMFPYPSGSGLHMGHIASYTPTDIISRY  62
            HT IE+KWQ  WAD++++K+  ++++PK+YALDMFPYPSG+GLH+GH  +YT+TDI+SR+
Sbjct  6    HTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSRF  65

Query  63   KRTKGFNVLHPMGYDAFGLPAEQYAIQTGVHPAITTEKSIASFRATLQRYGFSFDWSREI  122
            KR++G NVLHPMG DAFGLPAEQYA++TG +PA  T  +IA+F+  ++  GFS+DW RE+
Sbjct  66   KRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDREV  125

Query  123  STCEPDYYKWTQFIFLKLFEKGLAYQKEVPVNWCPALKTVLANDEVI-DGKSERGGHPVI  181
            +T +P+YYKWTQ IF KL+EKGLAY+ EVPVNW   L T +AN+EV+ DG SERGG PV+
Sbjct  126  NTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVV  185

Query  182  RVPMKQWMLKITDYAERLLQDLDKIDWPERTKEAQRNWIGKSEGATVRFNIKNFPEDSFE  241
            R PM+QWMLKIT YAERLL+DL+ +DWPE  K+ QRNWIGKS GA V F++K+  +  F 
Sbjct  186  RKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKD-TDKDFT  244

Query  242  IFTTRPDTIFGVSFMVLAPEHPLVKKICTPDQSSRVSDYIASTAGKSEVDRKA-NTEKTG  300
            +FTTRPDT+FG ++ VLAPEH+LV  I T+DQ+  V+DY   ++ KS++ R     EKTG
Sbjct  245  VFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTG  304

Query  301  VFTGAYALNPVSQKEIPIWIADYVMMDYGSGAIMAVPGHDERDFEFAQKFDLPVVRVLES  360
            V TG+YA+NPV+ KE+P+WIADYV+  YG+GAIMAVP+HDERD EFA++F+L ++ VLE+
Sbjct  305  VWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEG  364

Query  361  ET--DLPFTGEGKLCNSDFLNGLTKTDAIQKMFTFLEEKNLGKKQIQYKLRDWLFSRQRY  418
                + +FT +G   NSDFL+GL K+ AI KM   LE   +G+ ++ Y+LRDWLFSRQRY
Sbjct  365  GNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRY  424

Query  419  WGEPFPILQTQDGKLQAVPENELPVLLPEVANYEPSDSGEAPLANNKEWVNYSAD----L  474
            WGEP+PI++ +DG   AVPE+ELP++LP   +  PS++GE+PLAN  +W++ + +     
Sbjct  425  WGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVKG  484

Query  475  KRETDTMPGAAGSSWYFLRYTDPRNSSAPFSTEAAQYWMPVDLYVGGAEHTVGHLLYSRF  534
            +RET+TMP  AGSSWY+LRY DP+N+      E  + W+PVD+YVGGAEH+V HLLY+RF
Sbjct  485  RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARF  544

Query  535  WTKVLFDVGLSPVDEPFQKLAHQGMILGP-------------------------------  563
            W KVL+D+G+ P  EPFQKL +QGMILG                                
Sbjct  545  WHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEEL  604

Query  564  --DGEKMSKSRGNVIPADEVAKDSGVDALRCYICFLGPMDKDKPWNSSGIDGVKRFLDRL  621
                 KMSKS  NV+ +D+V  + G D+LR Y  F+GP+D   +W+  G++G ++FLDR+
Sbjct  605  EQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRV  664

Query  622  TRLAINETTGESIATDSELPAEVEKLLHKTIKKVSEDIEAMSFNTCISQMMILVNELYKH  681
             RL       E      E ++ ++K+ + T+K V+E+++ M FNT I+Q+M++VN   K+
Sbjct  665  YRLITTKEITE------ENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKE  718

Query  682  DCKSKKVllplaqllqpfapHTAEELWSKLGGDGLVVT-AAWPQFKPELCTDDTVTLGVQ  740
            D         + QL+ PFAPH +EELW  L + G  ++  +WP +      ++ V + VQ
Sbjct  719  DKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQ  778

Query  741  VNGKMRGTIEISvtadeaeavaaamkvatvtsaLAQQTPTKVIYKAGKILNLI  793
            ++GK+++ + ++      E    A+    V + +A +   KVI  + K++N++
Sbjct  779  IKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIV  831

624) leuS in NC_007899


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  674 bits (2548),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 410/833 (50%), Positives = 602/833 (73%), Gaps = 19/833 (2%)

Query  3    YDPSLIEKKWQEFWKEHKSFKANEADDKPKYYVLDMFPYPSGAGLHVGHLIGYTATDIVA  62
            YD + IE KWQ FW ++ +FK+     KPK+Y LDMFPYPSGAGLHVGH  GYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRAKGFSVLHPMGWDSFGLPAEQYAVRTGTHPRETTQKNIENFRKQLSAMGFSYDEGR  122
            R+KRA+G +VLHPMGWD+FGLPAEQYA+ TG +P E T  NI NF++Q++A+GFSYD +R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EFATSDPEYYRWTQKLFLLLYEKGLAYMADMAVNYCPELGTVLSNEEV-ENGLSIEGGYP  181
            E  T+DP+YY+WTQ +F  LYEKGLAY A+++VN   ELGT ++NEEV  +G S  GGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRMLRQWILRITAYSDQLLEGLEGLDWPENVKQLQRNWIGKSEGALVRFKVN--NQNF  239
            V R+ +RQW+L+ITAY+++LLE+LE +DWPE++K++QRNWIGKS GA V FKV+  +++F
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  240  LEVFTTRPDTLCGVSFLVIAPEHPEVGQLIAEDRREEVEAYICRAQSKSERDRISESKIK  299
              VFTTRPDTL G ++ V+APEH+ V+ + + D+ E V  Y  +A  KS+  R   +K K
Sbjct  244  -TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEK  302

Query  300  SGVFTGTYAKHPITGADIPIWVSDYVILGYGSGVVMGVPAHDERDREFAETFSLPIYEVL  359
            +GV TG+YA +P+ G ++P+W++DYV+ +YG+G +M+VPAHDERD+EFA  F+L I  VL
Sbjct  303  TGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL  362

Query  360  DTD-----GYCIHSNH--GDFLLDGLWGREAQDYVIAYLQKKNLGESKVAYKLRDWLFSR  412
            + +     ++  ++ H  +DF LDGL    A   ++  L+   +G+ +V+Y+LRDWLFSR
Sbjct  363  EGGNVEEAAFTEDGLHINSDF-LDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSR  421

Query  413  QRYWGEPIPIIHFEDGTCRpleddelpllppeIQDYRPEGFGQGPLAKVKEWVDIHDKKT  472
            QRYWGEPIPIIH EDGT  ++ + ELPL+ P  +D RP G G++PLA+V +W+++  +  
Sbjct  422  QRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV-TRED  480

Query  473  NRQGRRETHTMPQWAGSCWYYLRFCDALNSQAPWSNEKEKYWMPVDLYIGGAEHAVLHLL  532
              +GRRET+TMPQWAGS WYYLR+ D+ N++    +E  K W+PVD+Y+GGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  533  YSRFWHRVFYDAGMVSTPEPFKKLINQGLVLATSYRIPGKGYVYPEDAHEDNGVWMST-S  591
            Y+RFWH+V+YD G+V+T EPF+KL+NQG++L+TSYR +  + V  +  +  +G      +
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  592  GEELEVRQEKMSKSKLNGVDPQILIEEFGADALRMYAMFSGPLDKNKLWCNQGVSGCRRF  651
            GEELE    KMSKS  N V+P+ ++E++GAD+LR+Y MF GPLD +  W ++G+ G R+F
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  652  LNRFYELVTSSLVQDIDDPKGMYLAHRLVHRVGEDIEKMSLNTIPSSFMEFINEFVKLD-  710
            L+R Y L+T+  + + +      + +  V  V E++++M +NT  + +M F+N   K D 
Sbjct  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  711  IYPKSALAMVVRALAPIAPHISEELWTIL-GNAPGIDQAGWPEVDPKYLEDTSVTFVIQV  769
            +++  A +  V+ +AP+APH++EELW  L +++ +I    WP  D   L +  V +V+Q+
Sbjct  721  LFSDYAKGF-VQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQI  779

Query  770  NGKLRARLDISKNAAREEV--LSLAREAVSRYLEDKEVKKEIFVPNRLVNFVL  820
            +GK++A+L ++K+ +REE+  ++LA E V   + +K++ K I VPN+LVN+V+
Sbjct  780  KGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

625) Ethha_0328 in NC_014828


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  673 bits (2545),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 415/835 (50%), Positives = 570/835 (69%), Gaps = 42/835 (5%)

Query  3    YDFAAIEKKWQKLWEETGVFHAKNDFSLPKFYALVEFPYPSGQGLHVGHPRSYTALDIVS  62
            YD +AIE KWQ +W +   F +  D S PKFYAL  FPYPSG GLHVGHP +YTA DI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RKRRLEGYNVLYPMGWDAFGLPTENFAIKNHIHPEIVTKNNVAHFKQQLQSLGLSFDWSR  122
            R +R +G NVL PMGWDAFGLP+E++A+    +P   T +N+A+FK+Q+++LG+S+DW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EINTTDPLYYRWTQWIFLQLFKKGLAYKKEMRVNWCTSCKCVLANEEVV-NGVCERCGSE  181
            E+NTTDP YY+WTQWIF +L+ KGLAY  E+ VNW       +ANEEV+ +G  ER G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VVHKVKSQWMLKITDYAQRLIDDLDGLDYIERVKTQQKNWIGRSTGAQVRFDTAAGD-PL  240
            VV+K   QWMLKIT YA+RL++DL+ +D  E +K  Q+NWIG+STGA+V F     D  +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  LIYTTRPDTIFGATYMVIAPEHPILEKWADKIENLDAVRAYQDEAAHKSDFERTEVQKDK  300
             ++TTRPDT+FGATY V+APEH++++      ++ +AV  Y+ +A+ KSD+ RT++ K+K
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDA-ITTSDQAEAVADYKRQASLKSDLARTDLAKEK  302

Query  301  TGVEIKGVRAVNPATGKEIPIFLSDYVLVTYGTGAIMAVPAHDERDFAFARTFGLPVVEV  360
            TGV   G  A+NP  GKE+P+ ++DYVL +YGTGAIMAVPAHDERD  FA+ F L ++ V
Sbjct  303  TGV-WTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  361  VAGGNVEQEAFTDCATGTMVNSGFLDGLTVEEAKEKIIAWLEETGRGEAKVNYKLRDWVF  420
            + GGNVE+ AFT+   G  +NS+FLDGL    A  K++ WLE  G G+ +V Y+LRDW+F
Sbjct  362  LEGGNVEEAAFTE--DGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLF  419

Query  421  SRQRYWGEPIPLVYCEKCGWVPVPEDQLPLRLPEVASYEPTDNGESPLAAMTDWVNTVCP  480
            SRQRYWGEPIP++  E     +VPE +LPL LP      P++ GESPLA +TDW++ V  
Sbjct  420  SRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE-VTR  478

Query  481  HCGGPARRETDTMPQWAGSSWYFLRYTDPHNGKALASPEALRYWLPVDWYNGGMEHTTLH  540
            + G  +RRET+TMPQWAGSSWY+LRY DPHN   LA  E L+ WLPVD Y GG EH+ LH
Sbjct  479  EDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLH  538

Query  541  LLYSRFWHKALFDLGIVPTSEPYQKRTSHGMILG--------------------------  574
            LLY+RFWHK L+DLG+VPT EP+QK  ++GMILG                          
Sbjct  539  LLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHV  598

Query  575  -------ENGEKMSKSRGNVVNPDEMVKAYGADTLRLYEMFIGDFEKAAPWSDTGIRGSK  627
                   +   KMSKS  NVVNPD++V  YGADTLR+YEMF+G ++ + +WS+ G+ GS+
Sbjct  599  ETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSR  658

Query  628  RFLERVWNLQEKLLPGDGYRPELESDLHKTIKKVTGDIESMKFNTAIAALMTLLNRFAKE  687
            +FL+RV  L       +     L+   + T+K VT +++ MKFNTAIA LM ++N   KE
Sbjct  659  KFLDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKE  718

Query  688  GASRGEW-RTFLLLLNPFAPHITEELWE-VTGLGGRLNAQKWPTYDEAKCVDARVRIAVQ  745
            +   ++  + F+ L+ PFAPH+ EELW+ +T+ G  ++   WP+YDE+K V+  V I VQ
Sbjct  719  DKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQ  778

Query  746  VCGKLRGTVEMdadadqqtvqtaaLELPRVQANVEGKQVVKVIFIKGKLINIVAK  800
            + GK+++ + +  D  ++ +Q  AL   +VQA++ GK+++KVI +  KL+NIV K
Sbjct  779  IKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

626) leuS in NC_020248


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  672 bits (2541),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 400/822 (49%), Positives = 587/822 (72%), Gaps = 23/822 (2%)

Query  3    YDPSLIEKKWQQFWKEHKSFKADETAGKPKYYVLDMFPYPSGAGLHVGHLIGYTATDIVA  62
            YD + IE KWQ FW ++ +FK++  A+KPK+Y LDMFPYPSGAGLHVGH  GYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRAKGFSVLHPMGWDSFGLPAEQYAVRTGTHPRETTKKNIENFRKQLSAMGFSYDEGR  122
            R+KRA+G +VLHPMGWD+FGLPAEQYA+ TG +P E T  NI NF++Q++A+GFSYD +R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EFATSDPDYYRWTQKLFLFLYEKGLAYMADMAVNYCEELGTVLANEEV-ENGLSVEGGYP  181
            E  T+DP+YY+WTQ +F  LYEKGLAY A+++VN  EELGT +ANEEV  +G S  GGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRMLRQWILRITAYSDQLLQGLEDLDWPENVKQLQRNWIGKSEGALVRFEV-DNGNFL  240
            V R+ +RQW+L+ITAY+++LL++LE++DWPE++K++QRNWIGKS GA V F V D ++ +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  SVFTTRPDTLCGVSFLVMAPEHPEINHLVSEEQRSAVENYIRCVQSKSERERISETKVKS  300
            +VFTTRPDTL G ++ V+APEH+ ++ + + +Q  AV +Y R    KS+  R   +K K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  301  GVFIGAYAKHPITGAPLPIWVSDYVIMGYGSGVVMGVPAHDERDREFANAFALPISEVLD  360
            GV  G+YA +P+ G  +P+W++DYV+ +YG+G +M+VPAHDERD+EFA+ F L I  VL+
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  361  DNG--QCIHSNHG-----DFLLNGLRGKEASDYVIAYLQKKNLGEAKVVYKLRDWLFSRQ  413
            +    +   +++G     DF L+GL    A   ++  L+   +G+ +V Y+LRDWLFSRQ
Sbjct  364  GGNVEEAAFTEDGLHINSDF-LDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQ  422

Query  414  RYWGEPIPIIHFEDGTCRpleddelpllppeIQDYRPKGFGQGPLANVKEWVEIHDVKTN  473
            RYWGEPIPIIH EDGT  ++ + ELPL+ P  +D RP G G++PLANV +W+E+      
Sbjct  423  RYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTR-EDG  481

Query  474  RKGRRETHTMPQWAGSCWYYLRFCDAHNSQAPWSNENERYWMPVDLYIGGAEHAVLHLLY  533
             KGRRET+TMPQWAGS WYYLR+ D+HN++    +E  + W+PVD+Y+GGAEHAVLHLLY
Sbjct  482  VKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLY  541

Query  534  SRFWHRVFYEAGLVSTPEPFKKLINQGLVLATSYRIPGKGYVHPEDVREDNGK-WTTASG  592
            +RFWH+V+Y+ G+V+T EPF+KL+NQG++L+TSYR +  + V  + V   +G      +G
Sbjct  542  ARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETG  601

Query  593  EELEVRQEKMSKSKLNGVDPQTLIDEFGADALRMYAMFSGPLDKNKLWCNHGVSGCRRFL  652
            EELE    KMSKS  N V+P+ +++++GAD+LR+Y MF GPLD +  W ++G+ G R+FL
Sbjct  602  EELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFL  661

Query  653  NRFYELVTSSAVQDVDDPKGMALAHKLVHRVGEDIEKMSLNTIPSSFMEFINEFTK----  708
            +R Y L+T+  + + +      + +  V  V E++++M +NT  + +M F+N   K    
Sbjct  662  DRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKL  721

Query  709  LDTYPKSALAMVVRALAPIAPHISEELWTIL-GYAPGIDKAGWPEVDPKYLEDASVTFVI  767
            +  Y+K+ + ++    AP+APH++EELW  L + + +I    WP  D   L +  V +V+
Sbjct  722  FSDYAKGFVQLI----APFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVV  777

Query  768  QVNGKLRARLDIDKNTSQEDI--LSAARESVAKYLEDKEIKK  807
            Q++GK++A+L + K+ S+E++  ++ A E V   + +K+I K
Sbjct  778  QIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIK  819

627) leuS in NC_002771


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  671 bits (2537),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 427/848 (51%), Positives = 586/848 (70%), Gaps = 60/848 (7%)

Query  2    YNHKEIEKKWQKIWDQSKAFKTGNKSDK-KYYVLDMFPYPSGSGLHVGHPEGYTATDIIA  60
            Y+H  IE KWQ +W ++ +FKTG  + K K+Y LDMFPYPSG+GLHVGHPEGYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  61   RFKRLKGFDVLHPMGWDAFGLPAEQYAISTGNNPNEFTQKNIATFKKQIKSLGLSYDFDK  120
            RFKR +G +VLHPMGWDAFGLPAEQYA+ TGN+P EFT  NIA FK+QI++LG+SYD D+
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  121  EVNTTDPKFYEQTQWIFKELYKKGLAVLADIDVNWCEELGTVLANEEVLIDKDGNKVSER  180
            EVNTTDP++Y  TQWIF  LY KGLA  A++ VNW EELGT +ANEEVL     +  SER
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVL----PDGTSER  179

Query  181  GSFPVVKKKMRQWVLKITNYADKLLEGLEDLDWENSLKLLQKNWIGKSTGTKVKFALELL  240
            G++PVV+K MRQW+LKIT YA++LLE+LE++DW +S+K +Q+NWIGKSTG++V F +   
Sbjct  180  GGYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDT  239

Query  241  DESIEVFTTRIETIFGATFLTISPEHPLVEKIVTSENKEKVKDFIKEFEKLDDRQKAD-K  299
            D  + VFTTR +T+FGAT+  ++PEH+LV+ I TS++ E V D+ ++     D  ++D  
Sbjct  240  DKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA  299

Query  300  NEKNGIFTGSYAINPFNQKKIPIWIGDFVLLSYGTGAIMSVPAHDKRDYEFANKYGLEIK  359
            +EK G+ TGSYAINP N K +P+WI+D+VL SYGTGAIM+VPAHD RD EFA+++ L+I 
Sbjct  300  KEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDII  359

Query  360  QVIVSKENVELPYLESGHLINSSEFNGLSSKEAIEKLNQYVEKNNLGQVETFYKLRDWIF  419
             V+ + +  E ++ E G  INS  ++GL    AI K+ + +E + +G+ +  Y+LRDW+F
Sbjct  360  PVLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLF  419

Query  420  SRQRYWGEPFPVA-FDDENNVYLIDGLVE--LPFMENIKPSKNGQSPLFNNKKWLYFEK-  475
            SRQRYWGEP+P+   +D  +  + ++ +   LP   +I+PS  G+SPL N   WL   + 
Sbjct  420  SRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRE  479

Query  476  DGKKLTRETNTMPQWAGSNWYYLAYILKNADGSYEKLDSEEAKKRFKKWLPVDLYIGGQE  535
            DG K  RETNTMPQWAGS+WYYL YI  +     EKL  EE    +K+WLPVD+Y+GG E
Sbjct  480  DGVKGRRETNTMPQWAGSSWYYLRYIDPHNT---EKLADEEL---LKQWLPVDIYVGGAE  533

Query  536  HAVLHLLYSRFWHRFLYDIGVVPTKEPFQKVVNQGMILGT--------------------  575
            HAVLHLLY+RFWH+ LYD+GVVPTKEPFQK+ NQGMILGT                    
Sbjct  534  HAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDG  593

Query  576  -------------DGQKMSKSRGNIINPSEIVDELGADTLRVYEMFMGPLTDDKDWQVES  622
                            KMSKS  N++NP ++V++ GADTLRVYEMFMGPL     W  E+
Sbjct  594  SFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEG  653

Query  623  IKGIRKWLERVYRLFEMFFDGQKTIEKSNEDHLILSQ-YNKLIKEIENEVELLKFNTAIS  681
            + G RK L+RVYRL+        T E ++E+   L + YN  +K + ++V+ +KFNTAI+
Sbjct  654  LEGSRKFLDRVYRLI-------TTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIA  706

Query  682  KLMVFVNLLYKVEKIPSWEILKNFALILSLFAPHIAEELLEKMNQK--QVKDQIWPTYDP  739
            +LMVFVN   K +K+ S +  K F  +++ FAPH++EEL + +      +    WP+YD 
Sbjct  707  QLMVFVNAANKEDKLFS-DYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDE  765

Query  740  TYLESNLTKYVIQINGKVRAIVDFELDKTQEEVLAKAMQIEKIKTLLENKNIIKVIFVAN  799
            + L  N    V+QI+GKV+A +    D ++EE+   A+  EK+++ +  K+IIKVI V+N
Sbjct  766  SKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPN  825

Query  800  KVLNLIVK  807
            K++N+++K
Sbjct  826  KLVNIVIK  833

628) Sinac_3050 in NC_019892


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  670 bits (2534),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 471/944 (50%), Positives = 626/944 (67%), Gaps = 118/944 (12%)

Query  1    MPAYHVQRIEKKWQAYWERNKTFRTPDVAPGKPKLYVLDMFPYPSGAGLHVGHPEGYTAT  60
            M  Y+   IE KWQA+W  N TF+T +  ++KPK+Y LDMFPYPSGAGLHVGHPEGYTAT
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKT-GTDASKPKFYALDMFPYPSGAGLHVGHPEGYTAT  59

Query  61   DIVCRYKRMRGFNVLHPMGWDAFGLPAEQYAIKTGTHPRITTQNNIDNFRRQIKSLGFSY  120
            DI+ R+KR +G NVLHPMGWDAFGLPAEQYA+ TG +P   T +NI NF+RQI++LGFSY
Sbjct  60   DILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSY  119

Query  121  DWDREIDTTDPHYYKWTQWIFLQLFDTWYDPDFAWTDPDGRPRKGKGRPIAELPIPAGTA  180
            DWDRE++TTDP+YYKWTQWI    F   Y+                              
Sbjct  120  DWDREVNTTDPNYYKWTQWI----FTKLYE------------------------------  145

Query  181  NPDAYRDSKRLAYRAEVPVNWCPELGTVLANEEVI-DGKSERGNHPVVRMPLKQWMLRIT  239
                    K LAY AEVPVNW  ELGT +ANEEV+ DG SERG  PVVR P++QWML+IT
Sbjct  146  --------KGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKIT  197

Query  240  AYADRLAEEIEFVDWPRAIKEMQRNWIGRSEGAEVDFFVGQDVSQWREGRRASGWPESPG  299
            AYA+RL E++E VDWP +IK+MQRNWIG+S GA+V F V +                   
Sbjct  198  AYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKD------------------T  239

Query  300  NDAIRVFTTRPDTLFGATYMVLAPEHPLVDRLTTPDRREAVESYRRATSGKSDLDRTDLA  359
            +  + VFTTRPDTLFGATY VLAPEH+LVD +TT+D+ EAV  Y+R +S KSDL RTDLA
Sbjct  240  DKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA  299

Query  360  KTKSGVFIGASAVNPVTGRSIPIWIADYVLMGYGTGAIMAVPGHDIRDFEFAQKFALPIL  419
            K K+GV  G+ A+NPV G+ +P+WIADYVL +YGTGAIMAVP+HD RD EFA++F L I+
Sbjct  300  KEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDII  359

Query  420  RVVARSadlagaaletaeaeYGVAVNSHGGVDGVSIDGLPTDQAKASITTWLEQHGLGHK  479
             V+  +    +A  E      G+ +NS+       +DGL    A A +  WLE +G+G+ 
Sbjct  360  PVLEGGNVEEAAFTED-----GLHINSD------FLDGLDKASAIAKMVEWLEAEGVGNE  408

Query  480  TVNYKLRDWLFSRQRYWGEPFPILLGEGETLKavpeaelpvllpelaDFRPSGKPEPPLG  539
             V Y+LRDWLFSRQRYWGEP+PI+  E+ T  AVPE+ELP++LP   D+RPSG  E+PL+
Sbjct  409  NVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLA  468

Query  540  KATDWIQYSSTY----QRETNTMPQWAGSCWYFLRYLDPTNDKRPWNPELEKYWMPVDLY  595
            + TDW++ +       +RETNTMPQWAGS WY+LRY+DP N  +  + EL K W+PVD+Y
Sbjct  469  NVTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIY  528

Query  596  VGGAEHAVLHLLYSRFWHKLLFDRGHVSTPEPFQRLVNQGMILGETEYTGYQNEADRWVS  655
            VGGAEHAVLHLLY+RFWHK+L+D G V+T EPFQ+L NQGMILG    T+Y++  +  V+
Sbjct  529  VGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILG----TSYRDSRGALVA  584

Query  656  VAKVKETENGHADLEGQPVKPVKLEPEQVVKKGEGFVLADDPEIRIDARAHKMSKARGNV  715
              KV                          K++ +F   +  E  ++  + KMSK+  NV
Sbjct  585  TDKVE-------------------------KRDGSFFHVETGE-ELEQAPAKMSKSLKNV  618

Query  716  INPDVVVDEYGADSLRLYEMFMGPLEAVKPWNMKGVEGVFRFLSRAWRMIVDADAEALGL  775
            +NPD VV++YGAD+LR+YEMFMGPL+A  +W+  G+EG  +FL R  R+I   +      
Sbjct  619  VNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITEEN-  677

Query  776  DPKVQDVPLTPDQAKLVARTVAAVSDDLDAMRFNTAISRLMEFTNAFTGQDVRPKSAMET  835
                     +    K+   TV AV++++D M+FNTAI++LM F NA   +D         
Sbjct  678  ---------SGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKG  728

Query  836  FTLLLAPMAPHIAEELWE-LLGHTDTLAYHPWPTFDPALLKDDEVEVPVQVNGKVRGRVV  894
            F  L+AP APH++EELW+ L +  ++++Y PWP++D + L +++VE+ VQ++GKV++++V
Sbjct  729  FVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLV  788

Query  895  VPadagrdaieaaaradekvaaLLEGKAIKKVIVVPGKLVNFVV  938
            V+ D +R+ ++  A A+EKV A + GK I KVI VP KLVN+V+
Sbjct  789  VAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

629) leuS in NC_014614


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  668 bits (2524),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 404/834 (49%), Positives = 579/834 (70%), Gaps = 42/834 (5%)

Query  4    YNHKPIEKKWQDIWEEKGVFHASNDSDKEKFYPLVEFPYPSGQGLHVGHPRSYTALDVVA  63
            Y+H +IE KWQ +W ++  F ++ D+ K KFY+L  FPYPSG GLHVGHP +YTA D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RRRRLDGYNVLYPIGWDAFGLPTENYAIKNKIHPKIVTKDNIANFKRQLMSLGISFDWSR  123
            R +R +G NVL P+GWDAFGLP+E+YA+    +P   T +NIANFKRQ+ +LG+S+DW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EINTTDEGYYKWTQWIFIQLFNKGLAYKNKMPINWCNSCKVGLANEEVI-QGTCERCGGE  182
            E+NTTD  YYKWTQWIF +L++KGLAY   +P+NW +    ++ANEEV+ +GT ER G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VVRKEKNQWMLKITEYADRLIDDLDLVNYIDRVKIQQKNWIGRSYGMEIKFPVDDT--SL  240
            VVRK   QWMLKIT YA+RL++DL+ V+  + +K  Q+NWIG+S G ++ F V DT   +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  TVFTTRPDTIYGATYMVISPEHPIIQEKSHKIQNLDEVLAYKEEAAKKSEFERTEVNTEK  300
            TVFTTRPDT++GATY V++PEH++++  +   Q  + V  YK +A+ KS++ RT++  EK
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQA-EAVADYKRQASLKSDLARTDLAKEK  302

Query  301  TGVRVLGLDAVNPLTKQNIPLFVSDYVLMTYGTGAIMAVPGHDTRDHEFAKVFDLPIVEV  360
            TGV+  G  A+NP+  +++P+ ++DYVL +YGTGAIMAVP+HD RD EFAK F+L I+ V
Sbjct  303  TGVWT-GSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  361  VSGGNVQEEAFTDIDNGTIVNSPIIDGLSVKEAKEKISEYIEAQGLGTKKVNFKLRDWVF  420
            + GGNV+E AFT  ++G  +NS ++DGL    A  K+ E +EA+G+G  +V ++LRDW+F
Sbjct  362  LEGGNVEEAAFT--EDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLF  419

Query  421  SRQRYWGEPIPLVYCEKCGWVPLPDSELPLTLPEVESYEPTDDGESPLSKITDWVSTTCP  480
            SRQRYWGEPIP++  E     ++P+SELPL LP      P++ GESPL+++TDW+  T  
Sbjct  420  SRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRE  479

Query  481  CCSGPAQRETDTMPQWAGSSWYFLRYADPDNNEELASKKALDYWMPVDWYNGGMEHTTLH  540
              +  ++RET+TMPQWAGSSWY+LRY DP+N E LA    L  W+PVD Y GG EH+ LH
Sbjct  480  -DGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLH  538

Query  541  LLYSRFWHKVLYDIGVVTNPEPYAKRTSHGMILG--------------------------  574
            LLY+RFWHKVLYD+GVV   EP+ K  ++GMILG                          
Sbjct  539  LLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHV  598

Query  575  -------ENNEKMSKSRGNVVNPDEIVEEYGADTFRMYEMFIGDFEKSVPWSSLGIKGCR  627
                   +   KMSKS  NVVNPD++VE+YGADT+R+YEMF+G ++ S++WS  G+ G R
Sbjct  599  ETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSR  658

Query  628  RFIERTWKLQEMIREEDIFSDKIESSLHKTIKKVTEDYETLKFNTAIAAMMSLINEIYDI  687
            +F++R  +L       +  S+ ++   + T+K VTE+ + +KFNTAIA +M ++N     
Sbjct  659  KFLDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKE  718

Query  688  GGITKKDYQTFLILLNPVAPHVTEELWQ-LMGFDGFLNEAPWPKYDESKLVESTIEIPVQ  746
            + +     + F+ L+ P APH+ EELWQ L + +  ++  PWP YDESKLVE+ +EI VQ
Sbjct  719  DKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQ  778

Query  747  INGKVRGKIVVAANISQDEVITMAKSDLVVKDMLDGKEIKKIIYVPGKILNIVV  800
            I+GKV++K+VVA ++S++E+  +A ++  V+  + GK+I K+I VP K++NIV+
Sbjct  779  IKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

630) leuS in NC_004432


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  668 bits (2525),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 411/842 (49%), Positives = 585/842 (70%), Gaps = 56/842 (6%)

Query  2    YNHNLVEKKWRKIWKDSNLHTFKD--NLKKPKFYALDMFPYPSGAGLHMGHVKSYTPTDV  59
            Y+H  +E KW+ +W D+  HTFK   +  KPKFYALDMFPYPSGAGLH+GH  +YT+TD+
Sbjct  4    YDHTAIEPKWQAFWADN--HTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDI  61

Query  60   YARFKRYQGYSVLHPMGWDAFGLPAEQFALATKNHPATFTDQNINNFKLQIDQLGFWFDW  119
             +RFKR QG +VLHPMGWDAFGLPAEQ+A+ T N+PA FT +NI NFK QI+ LGF +DW
Sbjct  62   LSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDW  121

Query  120  NKEVNTTDPNFYKWTQWIFIKLFENGLAEIKDIDVNWCQELGTVLANEEVLTDEKGNKVS  179
            ++EVNTTDPN+YKWTQWIF KL+E+GLA   ++ VNW +ELGT +ANEEVL D      S
Sbjct  122  DREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDG----TS  177

Query  180  ERGKYPVIKKPMKQWVLKITKFADQLIDDLELTDWTVGLKNIQKKWIGKSIGATVKFKIQ  239
            ERG YPV++KPM+QW+LKIT +A++L++DLE  DW  ++K++Q++WIGKS GA V FK++
Sbjct  178  ERGGYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVK  237

Query  240  NSDSEIEVFTSRPDTIFGVSFIGLSSDHELV--LKEKTKNKKIEAFLNELSSLKEYERTA  297
            ++D ++ VFT+RPDT+FG ++  L+++H LV  +    +   +  +  + S   +  RT 
Sbjct  238  DTDKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTD  297

Query  298  INVEKKGVLLDIKAIHPITKQLVPVYVCNYVLSNYGNGAIMGVPAGDKRDYDFAKLFNLE  357
            +  EK GV  +  AI+P+  + +PV + +YVL++YG GAIM+VPA D RD +FAK FNL+
Sbjct  298  LAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLD  357

Query  358  IKEIIKD---HPAPYEEDGIHINSDFLNGLNNEDAIAKIVEYLEKNKIGKKQVNYKLKDW  414
            I  ++ +   + A++ EDG+HINSDFL+GL++  AIAK+VE LE + +G+ +V Y+L+DW
Sbjct  358  IIPVLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDW  417

Query  415  LFSRQRYWGEPFPVLF--DEKGNIIVEKNLPLLLPETNDIKPSGTGESPLANLTEWVNVK  472
            LFSRQRYWGEP+P++   D  +  + E +LPL+LP T+DI+PSGTGESPLAN+T+W++V 
Sbjct  418  LFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT  477

Query  473  IDSKL-YRRETNTMPQWAGSCWYYLAYLLKDGDSYLPLDSKQAYEIFKRWLPVDIYIGGQ  531
             +  +  RRETNTMPQWAGS WYYL Y+  +    L+ +     E++K+WLPVDIY+GG 
Sbjct  478  REDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADE-----ELLKQWLPVDIYVGGA  532

Query  532  EHAVLHLLYARFWHKFLHQINVVPNKEPFYKIINQGMILVNG------------------  573
            EHAVLHLLYARFWHK L ++ VVP KEPF K++NQGMIL  +                  
Sbjct  533  EHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRD  592

Query  574  ----------------EKMSKSKGNVVNPSDFVVSHGADALRLYMMFMGPITASLPWEES  617
                             KMSKS  NVVNP D V   GAD+LR+Y MFMGP+ AS++W E 
Sbjct  593  GSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEE  652

Query  618  GIDGMYKWVQRVYRLFETKQIDKNFNDENLEKKYHQFVKKASEFMENFDFNLVISEMMIF  677
            G++G  K ++RVYRL+ TK+I  + N   L+K Y++ VK  +E +++  FN  I+++M+F
Sbjct  653  GLEGSRKFLDRVYRLITTKEITEE-NSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVF  711

Query  678  INECYKYEKINYDYMLNFCVILSCFAPFITEEINEVFLKNKKFISDNLWPKYDEKKIVET  737
            +N   K +K+  DY   F  +++ FAP + EE+ + +  +   IS   WP YDE K+VE 
Sbjct  712  VNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVEN  771

Query  738  TIKIPVQINGKIREVLEINLGATQKDVVDLAiknekiikwienkkivkeiYIENKILNLI  797
             + I VQI+GK++  L +  + ++ ++ ++A+ NEK+   I  K I+K I + NK++N++
Sbjct  772  DVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIV  831

Query  798  IK  799
            IK
Sbjct  832  IK  833

631) Psta_1623 in NC_013720


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  668 bits (2524),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 456/956 (48%), Positives = 616/956 (65%), Gaps = 126/956 (13%)

Query  1    MPRYTPAAIEPKWQAFWEASQTFKSPEMPTSEKLYVLDMFPYPSGAGLHVGHPEGYTATD  60
            M  Y  +AIEPKWQAFW  ++TFK+   ++  K+Y LDMFPYPSGAGLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   IVCRYARMCGKSVLHPMGFDAFGLPAEEHAIKTNTPPRINTEQNIAEFTRQLKELGFSYD  120
            I+ R+ R  G +VLHPMG DAFGLPAE+ A+ T   P   T +NIA+F RQ++ LGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WSRVLATTDVEYFRWTQWIFLVLFDTWFDADQQRGRPISELPIPGDISGQGEEAIRKYQD  180
            W R + TTD +Y++WTQWIF  L++        +G                         
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYE--------KG-------------------------  147

Query  181  EHRLAFQSDALVNWCPGLGTVLANEEVI-DGKSERGGHPVQRIPLRQWMLRITSYAERLE  239
               LA++++  VNW   LGT +ANEEV+ DG SERGG PV R P+RQWML+IT+YAERL 
Sbjct  148  ---LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLL  204

Query  240  SDLEGLDWSEGIKKLQRDWIGKSVGAEVDFYIGPKTKFDAWKKSRAGQPFARKPADDVLR  299
             DLE +DW+E+IK +QR+WIGKS GA+V F +                    K +D  + 
Sbjct  205  EDLEEVDWPESIKDMQRNWIGKSTGANVTFKV--------------------KDTDKDFT  244

Query  300  IYTTRPDTLFGVTYMVIAPEHPFVATLTTAEQKSAVADYCAKAASKSDRDRQDVAKAKTG  359
            ++TTRPDTLFG TY V+APEH++V ++TT++Q  AVADY  +A+ KSD  R D+AK KTG
Sbjct  245  VFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTG  304

Query  360  VFSGSYALNPVSGQPVPIWIADYVLWGYGTGAIMAVPAHDDRDYEFAKQYGIPITavvap  419
            V +GSYA+NPV+G+ +P+WIADYVL +YGTGAIMAVPAHD+RD EFAKQ+ + I      
Sbjct  305  VWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDI------  358

Query  420  eapaasaseKELAHYQKQISGEACYTEYGRAINSSDKYNGLTTLEFKAKITADLATDGLG  479
                       ++  +     EA +TE G  INS D  +GL      AK+   L ++G+G
Sbjct  359  -----------IPVLEGGNVEEAAFTEDGLHINS-DFLDGLDKASAIAKMVEWLEAEGVG  406

Query  480  REAVNYKLRDWLFSRQRFWGEPFPILHELDENLNPTGMIRAVDPADLPVDLPYLEDYKPH  539
             E V Y+LRDWLFSRQR+WGEP+PI+H         G   AV  ++LP+ LP   D +P 
Sbjct  407  NENVTYRLRDWLFSRQRYWGEPIPIIH------WEDGTSTAVPESELPLVLPVTKDIRPS  460

Query  540  GRPEPPLAKAPDEWLYPT-IDGKRYRRETNTMPQWAGSCWYYLRFIDPKNDQVFVDREKE  598
            G  E+PLA+  D WL  T  DG + RRETNTMPQWAGS WYYLR+IDP N + + D E  
Sbjct  461  GTGESPLANVTD-WLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELL  519

Query  599  KAWMPIDLYVGGAEHAVLHLLYSRFWHKVLFDRGYVSTKEPFQKLVNQGMILGEVELTSY  658
            K W+P+D+YVGGAEHAVLHLLY+RFWHKVL+D G V+TKEPFQKL NQGMILG    TSY
Sbjct  520  KQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILG----TSY  575

Query  659  QTAGGTYISSADVRELEDGTFVTKSTGEAVSAVRVETSQVMKQGEHTVLVDHPSVRVESR  718
            + + G+ +++  V E  DG+F            +VET++ + Q+                
Sbjct  576  RDSRGALVATDKV-EKRDGSF-----------FHVETGEELEQAPA--------------  609

Query  719  AFKMSKSRGNVINPSTVIAEYGADSLRLYEMFMGPLEATKPWSMAGVSGVRSFLDRVWRL  778
              KMSKS  NV+NP  V+ +YGAD+LR+YEMFMGPL+A+ +WS  G+ G R FLDRV RL
Sbjct  610  --KMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRL  667

Query  779  MIDDRVDEMQLLEAVQDVEPTQEQLRLLHKTIKQVTYDLEHMQFNTSIARMMEFTNFFTK  838
            +    + E          E +    ++ + T+K VT ++++M+FNT+IA++M F N   K
Sbjct  668  ITTKEITE----------ENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANK  717

Query  839  EKVRPRSVMEKFVLLLSPLAPHIAEELWHML-GNKHSLAYEPWPKFDDALTRDAEVEIPV  897
            E          FV L++P+APH++EELW+ L ++ +S++Y PWP +D++   + +VEI V
Sbjct  718  EDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVV  777

Query  898  QILGKLRSKVVVAAGSDQETLIAAAKADPRIIELLTGKEIVKTIVVPGKLINFVVK  953
            QI GK+++K+VVA +  +E L   A A+ ++   ++GK+I+K I VP KL+N+V+K
Sbjct  778  QIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

632) leuS in NC_002179


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  667 bits (2521),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 412/839 (50%), Positives = 601/839 (72%), Gaps = 31/839 (3%)

Query  3    YDPNLIEKKWQQFWKEHRSFQANEDEDKVKYYVLDMFPYPSGAGLHVGHLIGYTATDIVA  62
            YD   IE KWQ FW ++++F++  D  K K+Y LDMFPYPSGAGLHVGH  GYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRARGFSVLHPMGWDSFGLPAEQYAIRTGTHPKVTTQKNIANFKKQLSAMGFSYDEGR  122
            R+KRA+G +VLHPMGWD+FGLPAEQYA+ TG +P   T  NIANFK+Q++A+GFSYD +R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EFATSDPDYYHWTQKLFLFLYDQGLAYMADMAVNYCPELGTVLSNEEV-ENGFSIEGGYP  181
            E  T+DP+YY WTQ +F  LY++GLAY A+++VN   ELGT ++NEEV  +G S  GGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERKMLRQWILKITAYADKLLEGLDALDWPENVKQLQKNWIGKSEGALVTFHLTQ-EGSL  240
            V RK +RQW+LKITAYA++LLE+L+ +DWPE++K++Q+NWIGKS GA VTF + + +  +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  EAFTTRLDTLLGVSFLVIAPEHPDLDSIVSEEQRDEVTAYVQESLRKSERDRISSVKTKT  300
              FTTR DTL+G ++ V+APEH+ +D+I + +Q + V+ Y +++  KS+  R    K KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  301  GVFTGNYAKHPITGNLLPVWISDYVVLGYGTGVVMGVPAHDERDREFAEMFSLPIHEVID  360
            GV TG+YA +P+ G+ +PVWI+DYV+ +YGTG +M+VPAHDERD+EFA  F+L I  V++
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  361  ----------DNGVCIHSNYNDFCLNGLSGQEAKDYVINYLEMRSLGRAKTMYRLRDWLF  410
                      ++G+ I+S++    L+GL    A   +++ LE  ++G  +  YRLRDWLF
Sbjct  364  GGNVEEAAFTEDGLHINSDF----LDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLF  419

Query  411  SRQRYWGEPIPIIHFEDGTHRpleddelpllppNIDDYRPEGFGQGPLAKAQDWVHIYDE  470
            SRQRYWGEPIPIIH EDGT  ++ + ELPL+ P   D RP G G++PLA+  DW+++  E
Sbjct  420  SRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRE  479

Query  471  KTGRPGCRETYTMPQWAGSCWYYLRFCDAHNSQLPWSKEKESYWMPVDLYIGGAEHAVLH  530
               + G RET TMPQWAGS WYYLR+ D+HN++     E    W+PVD+Y+GGAEHAVLH
Sbjct  480  DGVK-GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLH  538

Query  531  LLYSRFWHRVFYDAGLVSTPEPFKKLINQGLVLASSYRIPGKGYVSIEDVREENGTWIST  590
            LLY+RFWH+V+YD G+V+T EPF+KL+NQG++L++SYR +  + V+ + V   +G+ +  
Sbjct  539  LLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHV  598

Query  591  -CGEIVEVRQEKMSKSKLNGVDPQVLIEEYGADALRMYAMFSGPLDKNKTWSNEGVGGCR  649
              GE +E    KMSKS  N V+P+ ++E+YGAD+LR+Y MF GPLD + +WS+EG+ G R
Sbjct  599  ETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSR  658

Query  650  RFLNRFYDLVTSSEVQDIEDRDGLVLAHKLVFR-ITEHIEKMSLNTIPSSFMEFLNDFSK  708
            +FL+R Y L+T+ E+ + E+ ++L    +   + +TE++++M +NT  + +M F+N  +K
Sbjct  659  KFLDRVYRLITTKEITE-ENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANK  717

Query  709  ----LPVYSKRALSMAVRVLEPIAPHISEELWVILGNPP-GIDQAAWPQIDESYLVAQTV  763
                ++ Y+K      V+++ P+APH++EELW  L  +  +I   +WP  DES LV + V
Sbjct  718  EDKLFSDYAKG----FVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDV  773

Query  764  TFVVQVNGKLRGRLEVAKEAPKEEV--LSLSRSVVAKYLENAQIRKEIYVPNKLVNFVL  820
             +VVQ++GK++++L VAK+ ++EE+  ++L+   V   +   +I K I VPNKLVN+V+
Sbjct  774  EIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

633) leuS in NC_000922


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  667 bits (2521),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 412/839 (50%), Positives = 601/839 (72%), Gaps = 31/839 (3%)

Query  3    YDPNLIEKKWQQFWKEHRSFQANEDEDKVKYYVLDMFPYPSGAGLHVGHLIGYTATDIVA  62
            YD   IE KWQ FW ++++F++  D  K K+Y LDMFPYPSGAGLHVGH  GYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRARGFSVLHPMGWDSFGLPAEQYAIRTGTHPKVTTQKNIANFKKQLSAMGFSYDEGR  122
            R+KRA+G +VLHPMGWD+FGLPAEQYA+ TG +P   T  NIANFK+Q++A+GFSYD +R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EFATSDPDYYHWTQKLFLFLYDQGLAYMADMAVNYCPELGTVLSNEEV-ENGFSIEGGYP  181
            E  T+DP+YY WTQ +F  LY++GLAY A+++VN   ELGT ++NEEV  +G S  GGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERKMLRQWILKITAYADKLLEGLDALDWPENVKQLQKNWIGKSEGALVTFHLTQ-EGSL  240
            V RK +RQW+LKITAYA++LLE+L+ +DWPE++K++Q+NWIGKS GA VTF + + +  +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  EAFTTRLDTLLGVSFLVIAPEHPDLDSIVSEEQRDEVTAYVQESLRKSERDRISSVKTKT  300
              FTTR DTL+G ++ V+APEH+ +D+I + +Q + V+ Y +++  KS+  R    K KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  301  GVFTGNYAKHPITGNLLPVWISDYVVLGYGTGVVMGVPAHDERDREFAEMFSLPIHEVID  360
            GV TG+YA +P+ G+ +PVWI+DYV+ +YGTG +M+VPAHDERD+EFA  F+L I  V++
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  361  ----------DNGVCIHSNYNDFCLNGLSGQEAKDYVINYLEMRSLGRAKTMYRLRDWLF  410
                      ++G+ I+S++    L+GL    A   +++ LE  ++G  +  YRLRDWLF
Sbjct  364  GGNVEEAAFTEDGLHINSDF----LDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLF  419

Query  411  SRQRYWGEPIPIIHFEDGTHRpleddelpllppNIDDYRPEGFGQGPLAKAQDWVHIYDE  470
            SRQRYWGEPIPIIH EDGT  ++ + ELPL+ P   D RP G G++PLA+  DW+++  E
Sbjct  420  SRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRE  479

Query  471  KTGRPGCRETYTMPQWAGSCWYYLRFCDAHNSQLPWSKEKESYWMPVDLYIGGAEHAVLH  530
               + G RET TMPQWAGS WYYLR+ D+HN++     E    W+PVD+Y+GGAEHAVLH
Sbjct  480  DGVK-GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLH  538

Query  531  LLYSRFWHRVFYDAGLVSTPEPFKKLINQGLVLASSYRIPGKGYVSIEDVREENGTWIST  590
            LLY+RFWH+V+YD G+V+T EPF+KL+NQG++L++SYR +  + V+ + V   +G+ +  
Sbjct  539  LLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHV  598

Query  591  -CGEIVEVRQEKMSKSKLNGVDPQVLIEEYGADALRMYAMFSGPLDKNKTWSNEGVGGCR  649
              GE +E    KMSKS  N V+P+ ++E+YGAD+LR+Y MF GPLD + +WS+EG+ G R
Sbjct  599  ETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSR  658

Query  650  RFLNRFYDLVTSSEVQDIEDRDGLVLAHKLVFR-ITEHIEKMSLNTIPSSFMEFLNDFSK  708
            +FL+R Y L+T+ E+ + E+ ++L    +   + +TE++++M +NT  + +M F+N  +K
Sbjct  659  KFLDRVYRLITTKEITE-ENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANK  717

Query  709  ----LPVYSKRALSMAVRVLEPIAPHISEELWVILGNPP-GIDQAAWPQIDESYLVAQTV  763
                ++ Y+K      V+++ P+APH++EELW  L  +  +I   +WP  DES LV + V
Sbjct  718  EDKLFSDYAKG----FVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDV  773

Query  764  TFVVQVNGKLRGRLEVAKEAPKEEV--LSLSRSVVAKYLENAQIRKEIYVPNKLVNFVL  820
             +VVQ++GK++++L VAK+ ++EE+  ++L+   V   +   +I K I VPNKLVN+V+
Sbjct  774  EIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

634) leuS in NC_002491


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  667 bits (2521),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 412/839 (50%), Positives = 601/839 (72%), Gaps = 31/839 (3%)

Query  3    YDPNLIEKKWQQFWKEHRSFQANEDEDKVKYYVLDMFPYPSGAGLHVGHLIGYTATDIVA  62
            YD   IE KWQ FW ++++F++  D  K K+Y LDMFPYPSGAGLHVGH  GYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRARGFSVLHPMGWDSFGLPAEQYAIRTGTHPKVTTQKNIANFKKQLSAMGFSYDEGR  122
            R+KRA+G +VLHPMGWD+FGLPAEQYA+ TG +P   T  NIANFK+Q++A+GFSYD +R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EFATSDPDYYHWTQKLFLFLYDQGLAYMADMAVNYCPELGTVLSNEEV-ENGFSIEGGYP  181
            E  T+DP+YY WTQ +F  LY++GLAY A+++VN   ELGT ++NEEV  +G S  GGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERKMLRQWILKITAYADKLLEGLDALDWPENVKQLQKNWIGKSEGALVTFHLTQ-EGSL  240
            V RK +RQW+LKITAYA++LLE+L+ +DWPE++K++Q+NWIGKS GA VTF + + +  +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  EAFTTRLDTLLGVSFLVIAPEHPDLDSIVSEEQRDEVTAYVQESLRKSERDRISSVKTKT  300
              FTTR DTL+G ++ V+APEH+ +D+I + +Q + V+ Y +++  KS+  R    K KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  301  GVFTGNYAKHPITGNLLPVWISDYVVLGYGTGVVMGVPAHDERDREFAEMFSLPIHEVID  360
            GV TG+YA +P+ G+ +PVWI+DYV+ +YGTG +M+VPAHDERD+EFA  F+L I  V++
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  361  ----------DNGVCIHSNYNDFCLNGLSGQEAKDYVINYLEMRSLGRAKTMYRLRDWLF  410
                      ++G+ I+S++    L+GL    A   +++ LE  ++G  +  YRLRDWLF
Sbjct  364  GGNVEEAAFTEDGLHINSDF----LDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLF  419

Query  411  SRQRYWGEPIPIIHFEDGTHRpleddelpllppNIDDYRPEGFGQGPLAKAQDWVHIYDE  470
            SRQRYWGEPIPIIH EDGT  ++ + ELPL+ P   D RP G G++PLA+  DW+++  E
Sbjct  420  SRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRE  479

Query  471  KTGRPGCRETYTMPQWAGSCWYYLRFCDAHNSQLPWSKEKESYWMPVDLYIGGAEHAVLH  530
               + G RET TMPQWAGS WYYLR+ D+HN++     E    W+PVD+Y+GGAEHAVLH
Sbjct  480  DGVK-GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLH  538

Query  531  LLYSRFWHRVFYDAGLVSTPEPFKKLINQGLVLASSYRIPGKGYVSIEDVREENGTWIST  590
            LLY+RFWH+V+YD G+V+T EPF+KL+NQG++L++SYR +  + V+ + V   +G+ +  
Sbjct  539  LLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHV  598

Query  591  -CGEIVEVRQEKMSKSKLNGVDPQVLIEEYGADALRMYAMFSGPLDKNKTWSNEGVGGCR  649
              GE +E    KMSKS  N V+P+ ++E+YGAD+LR+Y MF GPLD + +WS+EG+ G R
Sbjct  599  ETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSR  658

Query  650  RFLNRFYDLVTSSEVQDIEDRDGLVLAHKLVFR-ITEHIEKMSLNTIPSSFMEFLNDFSK  708
            +FL+R Y L+T+ E+ + E+ ++L    +   + +TE++++M +NT  + +M F+N  +K
Sbjct  659  KFLDRVYRLITTKEITE-ENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANK  717

Query  709  ----LPVYSKRALSMAVRVLEPIAPHISEELWVILGNPP-GIDQAAWPQIDESYLVAQTV  763
                ++ Y+K      V+++ P+APH++EELW  L  +  +I   +WP  DES LV + V
Sbjct  718  EDKLFSDYAKG----FVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDV  773

Query  764  TFVVQVNGKLRGRLEVAKEAPKEEV--LSLSRSVVAKYLENAQIRKEIYVPNKLVNFVL  820
             +VVQ++GK++++L VAK+ ++EE+  ++L+   V   +   +I K I VPNKLVN+V+
Sbjct  774  EIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

635) leuS in NC_005043


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  667 bits (2521),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 412/839 (50%), Positives = 601/839 (72%), Gaps = 31/839 (3%)

Query  3    YDPNLIEKKWQQFWKEHRSFQANEDEDKVKYYVLDMFPYPSGAGLHVGHLIGYTATDIVA  62
            YD   IE KWQ FW ++++F++  D  K K+Y LDMFPYPSGAGLHVGH  GYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRARGFSVLHPMGWDSFGLPAEQYAIRTGTHPKVTTQKNIANFKKQLSAMGFSYDEGR  122
            R+KRA+G +VLHPMGWD+FGLPAEQYA+ TG +P   T  NIANFK+Q++A+GFSYD +R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EFATSDPDYYHWTQKLFLFLYDQGLAYMADMAVNYCPELGTVLSNEEV-ENGFSIEGGYP  181
            E  T+DP+YY WTQ +F  LY++GLAY A+++VN   ELGT ++NEEV  +G S  GGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERKMLRQWILKITAYADKLLEGLDALDWPENVKQLQKNWIGKSEGALVTFHLTQ-EGSL  240
            V RK +RQW+LKITAYA++LLE+L+ +DWPE++K++Q+NWIGKS GA VTF + + +  +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  EAFTTRLDTLLGVSFLVIAPEHPDLDSIVSEEQRDEVTAYVQESLRKSERDRISSVKTKT  300
              FTTR DTL+G ++ V+APEH+ +D+I + +Q + V+ Y +++  KS+  R    K KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  301  GVFTGNYAKHPITGNLLPVWISDYVVLGYGTGVVMGVPAHDERDREFAEMFSLPIHEVID  360
            GV TG+YA +P+ G+ +PVWI+DYV+ +YGTG +M+VPAHDERD+EFA  F+L I  V++
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  361  ----------DNGVCIHSNYNDFCLNGLSGQEAKDYVINYLEMRSLGRAKTMYRLRDWLF  410
                      ++G+ I+S++    L+GL    A   +++ LE  ++G  +  YRLRDWLF
Sbjct  364  GGNVEEAAFTEDGLHINSDF----LDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLF  419

Query  411  SRQRYWGEPIPIIHFEDGTHRpleddelpllppNIDDYRPEGFGQGPLAKAQDWVHIYDE  470
            SRQRYWGEPIPIIH EDGT  ++ + ELPL+ P   D RP G G++PLA+  DW+++  E
Sbjct  420  SRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRE  479

Query  471  KTGRPGCRETYTMPQWAGSCWYYLRFCDAHNSQLPWSKEKESYWMPVDLYIGGAEHAVLH  530
               + G RET TMPQWAGS WYYLR+ D+HN++     E    W+PVD+Y+GGAEHAVLH
Sbjct  480  DGVK-GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLH  538

Query  531  LLYSRFWHRVFYDAGLVSTPEPFKKLINQGLVLASSYRIPGKGYVSIEDVREENGTWIST  590
            LLY+RFWH+V+YD G+V+T EPF+KL+NQG++L++SYR +  + V+ + V   +G+ +  
Sbjct  539  LLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHV  598

Query  591  -CGEIVEVRQEKMSKSKLNGVDPQVLIEEYGADALRMYAMFSGPLDKNKTWSNEGVGGCR  649
              GE +E    KMSKS  N V+P+ ++E+YGAD+LR+Y MF GPLD + +WS+EG+ G R
Sbjct  599  ETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSR  658

Query  650  RFLNRFYDLVTSSEVQDIEDRDGLVLAHKLVFR-ITEHIEKMSLNTIPSSFMEFLNDFSK  708
            +FL+R Y L+T+ E+ + E+ ++L    +   + +TE++++M +NT  + +M F+N  +K
Sbjct  659  KFLDRVYRLITTKEITE-ENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANK  717

Query  709  ----LPVYSKRALSMAVRVLEPIAPHISEELWVILGNPP-GIDQAAWPQIDESYLVAQTV  763
                ++ Y+K      V+++ P+APH++EELW  L  +  +I   +WP  DES LV + V
Sbjct  718  EDKLFSDYAKG----FVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDV  773

Query  764  TFVVQVNGKLRGRLEVAKEAPKEEV--LSLSRSVVAKYLENAQIRKEIYVPNKLVNFVL  820
             +VVQ++GK++++L VAK+ ++EE+  ++L+   V   +   +I K I VPNKLVN+V+
Sbjct  774  EIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

636) leuS in NC_017285


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  665 bits (2513),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 412/836 (50%), Positives = 600/836 (72%), Gaps = 25/836 (2%)

Query  3    YDPNLIEKKWQQFWKEHRSFQANEDEDKVKYYVLDMFPYPSGAGLHVGHLIGYTATDIVA  62
            YD   IE KWQ FW ++++F++  D  K K+Y LDMFPYPSGAGLHVGH  GYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRARGFSVLHPMGWDSFGLPAEQYAIRTGTHPKVTTQKNIANFKKQLSAMGFSYDEGR  122
            R+KRA+G +VLHPMGWD+FGLPAEQYA+ TG +P   T  NIANFK+Q++A+GFSYD +R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EFATSDPDYYHWTQKLFLFLYDQGLAYMADMAVNYCPELGTVLSNEEV-ENGFSIEGGYP  181
            E  T+DP+YY WTQ +F  LY++GLAY A+++VN   ELGT ++NEEV  +G S  GGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERKMLRQWILKITAYADKLLEGLDALDWPENVKQLQKNWIGKSEGALVTFHLTQ-EGSL  240
            V RK +RQW+LKITAYA++LLE+L+ +DWPE++K++Q+NWIGKS GA VTF + + +  +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  EAFTTRLDTLLGVSFLVIAPEHPDLDSIVSEEQRDEVTAYVQESLRKSERDRISSVKTKT  300
              FTTR DTL+G ++ V+APEH+ +D+I + +Q + V+ Y +++  KS+  R    K KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  301  GVFTGNYAKHPITGNLLPVWISDYVVLGYGTGVVMGVPAHDERDREFAEKFSLPIHEVID  360
            GV TG+YA +P+ G+ +PVWI+DYV+ +YGTG +M+VPAHDERD+EFA +F+L I  V++
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  361  ----------DDGVCIHSTYNDFCLNGLSGQEAKDYVINYLEMRSLGRAKTMYRLRDWLF  410
                      +DG+ I+S +    L+GL    A   +++ LE  ++G  +  YRLRDWLF
Sbjct  364  GGNVEEAAFTEDGLHINSDF----LDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLF  419

Query  411  SRQRYWGEPIPIIHFEDGTHRplehdelpllppNIDDYRPEGFGQGPLAKAQDWVHIYDE  470
            SRQRYWGEPIPIIH EDGT  ++ + ELPL+ P   D RP G G++PLA+  DW+++  E
Sbjct  420  SRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRE  479

Query  471  KTGRPGCRETYTMPQWAGSCWYYLRFCDAHNSQLPWSKEKETYWMPVDLYIGGAEHAVLH  530
               + G RET TMPQWAGS WYYLR+ D+HN++     E    W+PVD+Y+GGAEHAVLH
Sbjct  480  DGVK-GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLH  538

Query  531  LLYSRFWHRVFYDAGLVSTPEPFKKLINQGLVLAFSYRIPGKGYVSIEDVREENGTWIST  590
            LLY+RFWH+V+YD G+V+T EPF+KL+NQG++L+ SYR +  + V+ + V   +G+ +  
Sbjct  539  LLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHV  598

Query  591  -CGEIVEVRQEKMSKSKLNGVDPQVLIEEYGADALRMYAMFSGPLDKNKTWSNEGVGGCR  649
              GE +E    KMSKS  N V+P+ ++E+YGAD+LR+Y MF GPLD + +WS+EG+ G R
Sbjct  599  ETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSR  658

Query  650  RFLNRFYDLVTSSEVQDIEDRDGLVLAHKLVFR-ITEHIEKMSLNTIPSSFMEFLNDFSK  708
            +FL+R Y L+T+ E+ + E+ ++L    +   + +TE++++M +NT  + +M F+N  +K
Sbjct  659  KFLDRVYRLITTKEITE-ENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANK  717

Query  709  LP-VYSKHALSMAVRVLEPIAPHISEELWVILGNPP-GIDQAAWPQIDESYLVAQTVTFV  766
               ++S  A +  V+++ P+APH++EELW  L  +  +I   +WP  DES LV + V +V
Sbjct  718  EDKLFSDYAKGF-VQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  767  VQVNGKLRGRIEVAKEAPKEEV--LSLSRSVVAKYLENAQIRKEIYVPNKLVNFVL  820
            VQ++GK+++++ VAK+ ++EE+  ++L+   V   +   +I K I VPNKLVN+V+
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

637) Bdt_0357 in NC_019567


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  664 bits (2511),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 400/800 (50%), Positives = 559/800 (70%), Gaps = 46/800 (5%)

Query  1    MFPYPSASGLHVGHMASYTPGDIISRYKRVNGFNVLHPMGYDAFGLPAEQYAIQTGVHPA  60
            MFPYPS++GLHVGH  +YT+ DI+SR+KR +G NVLHPMG DAFGLPAEQYA++TG +PA
Sbjct  39   MFPYPSGAGLHVGHPEGYTATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPA  98

Query  61   ITTKKAIDSFRKTLQTFGFSFDWSREISTCEPDYYKWTQFIFLKLYERGLAYQKEVPVNW  120
              T   I +F++ ++++GFS+DW RE++T +P+YYKWTQ IF KLYE+GLAY+ EVPVNW
Sbjct  99   EFTAENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNW  158

Query  121  CPALKTVLANDEVV-DGKSERGGHPVIRVPMKQWMLKITDYAERLLNDLDKLDWPERTKE  179
               L T +AN+EV+ DG SERGG PV+R PM+QWMLKIT YAERLL+DL+ +DWPE  K+
Sbjct  159  VEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKD  218

Query  180  GQRNWIGKSEGARITFQVHGEKDTFEVFTTRPDTLFGVTFMVMAPEHPLVKKITSQPQYT  239
             QRNWIGKS GA +TF+V +    F VFTTRPDTLFG T+ V+APEH+LV  IT+  Q  
Sbjct  219  MQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAE  278

Query  240  AVENYIADTAKKSEVDRKA-STEKTGVFTGAHATHPITGDKIEIWISDYVLMDYGTGAIM  298
            AV +Y  +++ KS++ R   + EKTGV TG+ A +P+ G  + +WI+DYVL  YGTGAIM
Sbjct  279  AVADYKRQASLKSDLARTDLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIM  338

Query  299  AVPGHDARDFEFATKFNIPIKSVLESDLL---PFEGDSIMINSEFLDGLNKTEAISKMLK  355
            AVP+HD RD EFA +FN+ I +VLE++ +   +F  D++ INS+FLDGL+K+ AI+KM+ 
Sbjct  339  AVPAHDERDWEFAKQFNLDIIPVLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVE  398

Query  356  HLEENKLGVREVQYKLRDWLFSRQRYWGEPFPIVHFADG-SKGVPVNELPVILPEVADYE  414
             LE + +G  +V Y+LRDWLFSRQRYWGEP+PI+H  DG S +VP +ELP++LP   D  
Sbjct  399  WLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIR  458

Query  415  PADTGEAPLARNADWVKYM-DGDKEGRRETDTMPGAAGSSWYFLRYIDPKNTEAPFSPEA  473
            P++TGE+PLA  +DW+    +++  GRRET+TMP  AGSSWY+LRYIDP NTE     E 
Sbjct  459  PSGTGESPLANVTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEEL  518

Query  474  EKYWMPVDLYVGGPEHTVGHLLYARFWTKVLFDCGLVTHDEPFQKLAHQGMILGPD----  529
             K W+PVD+YVGG+EH+V HLLYARFW KVL+D G+V   EPFQKL +QGMILG      
Sbjct  519  LKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDS  578

Query  530  -----------------------------GEKMSKSRGNVISPEDIARSHGADALRTFIS  560
                                           KMSKS  NV++P+D+    GAD+LR +  
Sbjct  579  RGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEM  638

Query  561  FMGPVDKDKPWAPTGIDGVRRFLDRITRLVVNDDGQLVATSEALTPEIEKLVHKTIKKVT  620
            FMGP+D   +W+  G++G R+FLDR+ RL+   +      +E  +  ++K+ + T+K VT
Sbjct  639  FMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKE-----ITEENSGALDKVYNETVKAVT  693

Query  621  EDIESMSFNTAISAMMILVNELYRAECRSVLAVKPLVQILAPFAPHLAEELWEKMNGEGL  680
            E+++ M FNTAI+ +M++VN   + +       K +VQ++APFAPHL+EELW+ + + G 
Sbjct  694  EQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGE  753

Query  681  C-ALAPWPKYDNTLCADDTVTIGVQVNGKMRGTIEIGvaaseqealaaakavqqvaavlG  739
              +  PWP YD++   ++ V I VQ++GK+++ + ++   S +E    A A ++V A ++
Sbjct  754  SISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIA  813

Query  740  DKNPDKVIYKAGKILNLIVK  759
            +K+  KVI  + K++N+++K
Sbjct  814  GKDIIKVIAVPNKLVNIVIK  833

638) leuS in NC_011047


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  664 bits (2510),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 417/843 (50%), Positives = 589/843 (70%), Gaps = 51/843 (6%)

Query  6    YDFKKIEYKWQRYWLENKVFKTSDNFDKKKFYCLDMFPYPSAEGLHVGHIEGYTASDIFS  65
            YD   IE KWQ +W +N  FKT+ +  K KFY LDMFPYPS+ GLHVGH EGYTA+DI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  66   RFKKMQGYNVLHPFGWDSFGLPAEQYALKTGNNPRNFTYENIKNFKEQIIKMGKGVDWDK  125
            RFK+ QG NVLHP GWD+FGLPAEQYA+ TGN+P +FT ENI NFK QI  +G + DWD+
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  126  ELATSDNDFYHWTQWIFKKLYQKNLAVLKDLEVNFCEGLGTVLANEEIVSKDGKLFSERG  185
            E+ T+D ++Y WTQWIF KLY+K LA   ++ VN  E LGT +ANEE+++ +    SERG
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGT---SERG  180

Query  186  DFPVVKKTLKQWVLKITDYAERLLDDLELVDFPSNLKQIQRNWIGKSSGVIITFKVDGFS  245
            ++PVV+K ++QW+LKIT YAERLL+DLE VD P ++K++QRNWIGKS+G  +TFKV +  
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  246  ETFDVFTTRPDTIFGVTCCILAPEHILVKKITKTLFQKSIFDYIEQTKQKQELERS-IDK  304
              F VFTTRPDT+FG T  +LAPEH LV  IT +    ++ DY  Q+  K +L R+ + K
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  305  NKTGVFTGSYAINPVNQKKVPIWISDYILPHYGTGALAAVPAHDQRDFEFAKKYQLEIIS  364
            +KTGV TGSYAINPVN K +P+WI+DY+L+ YGTGA+ AVPAHD+RD EFAK+++L+II+
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  365  VIKDKDNQIQEVFCGDGIHFQSHFLDGLTNETAKIKIIEFLEKNKLGYIHNIYKLHDYFF  424
            V+ + + + +  F  DG+H++S+FLDGL + +A  K++E LE + +G  +  Y+L+D +F
Sbjct  361  VLEGGNVE-EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLF  419

Query  425  SRQRYWGEPFPVFYDEKDNIHllsdeelplelpylKDFKPSNNAKEAPPLSRVKNWIYFE  484
            SRQRYWGEP+P++  E +    +++ ELPL LP  KD++PS  +   +PL+ V +W+   
Sbjct  420  SRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTG--ESPLANVTDWLEVT  477

Query  485  K-NGKKYRRDANTMSQLAGSSWYYIAYILKNSLGMLPLNTLDSKKKIDYFLPVDLYIGGA  543
            + +G K RR++NTM+Q AGSSWYY+ YI  ++   L+ + L     +   LPVD+Y+GGA
Sbjct  478  REDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEEL-----LKQWLPVDIYVGGA  532

Query  544  EHSTGHLLCVRFWHKVLYDLGLVSTKEPFKKIIHQGIILG--------------------  583
            EH+  HLL  RFWHKVLYDLG+V+TKEPF+K+++QG+ILG                    
Sbjct  533  EHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRD  592

Query  584  -------------NDNTKMSKSKGNGVSAKLMLDQYGADVLRLYEMFLGPLSDTKIWSYK  630
                         +  +KMSKS  N V++  +++QYGAD LR+YEMF+GPL  +  WS  
Sbjct  593  GSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEE  652

Query  631  NIKGSIKFLERVYNIFNF-EITTINQKELEFLYHTTVKKVTDLYEKLKFNVAISQLMIFV  689
             + GS KFL+RVY ++   EIT  N   L+ +Y+ TVK VT+  +++KFN AI+QLM+FV
Sbjct  653  GLEGSRKFLDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFV  712

Query  690  NEVYKHKKI-SKYQARGFLKLLNPIAPHLTEEL-NQLFLNEKPICFSSFPSYDESFLSLK  747
            N   K+ K+ S Y A+GF++L+ P+APHL EEL + L  +  +I + + PSYDES L  +
Sbjct  713  NAANKEDKLFSDY-AKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVEN  771

Query  748  NVEIIIQINGKLRSKITSLMNESKENILKIALQDAkiinyihhkqkiqkiiFVNNKLLNI  807
            +VEI++QI+GK+++K+    + S+E++  +AL + K+   I  K+ I+ I  V NKL+NI
Sbjct  772  DVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIA-VPNKLVNI  830

Query  808  VLK  810
            V+K
Sbjct  831  VIK  833

639) FPR_03880 in NC_021020


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  663 bits (2507),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 434/848 (52%), Positives = 583/848 (69%), Gaps = 20/848 (2%)

Query  3    YDYKAVEAKWQKVWEDEKTFHVEIDHKKPKFYALVEFPYPSGAGLHVGHPRSYTALDVVS  62
            YD  A+E+KWQ  W D+ TF    D  KPKFYAL  FPYPSGAGLHVGHP +YTA D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RKRRKNGYNVLYPMGWDAFGLPTENFAMKNHIHPAIVTKSNVDHFRSQLKALGFSFDWDR  122
            R +R +G NVL PMGWDAFGLP+E++AM    +PA  T  N+ +F+ Q++ALGFS+DWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EINTTDPEYYKWTQWIFLQLYKHGLAYKKEMNVNWCTGCKCVLANEEVV-NGVCERCGSE  181
            E+NTTDP+YYKWTQWIF +LY  GLAY  E+ VNW       +ANEEV+ +G  ER G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VVHRVKSQWMLKITAYADKLIDGLDGLDYIERVSTQQKNWIGRSHGAEVNFGTTAGDT-L  240
            VV++   QWMLKITAYA++L+++L+ +D  E +   Q+NWIG+S GA+V F     D  +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  TVYTTRCDTLFGATYMVISPEHALLKAWLEKGIIKNaeavkayqaeaaRKSDFERSELNK  300
            TV+TTR DTLFGATY V++PEHAL+ A        +AEAV  Y+ +A+ KSD+ R++L K
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDA---ITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  301  EKTGVQLDGVMGINPVNETEIPIFISDYVLSTYGTGAIMAVPAHDTRDWEFAKKFGLPII  360
            EKTGV   G  +INPVN  E+P+ I+DYVL++YGTGAIMAVPAHD RDWEFAK+F L II
Sbjct  301  EKTGV-WTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDII  359

Query  361  EVVKGNTPSNLDEAAFTDVATGTLVNSGFLNGLSVVDAKKKMITWLEETGKGRDKVNYKL  420
             V+ G   +N++EAAFT+   G  +NS+FL+GL    A  KM+ WLE  G G ++V Y+L
Sbjct  360  PVLEG---GNVEEAAFTE--DGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRL  414

Query  421  RDWVFSRQRYWGEPIPMVHCDKCGWQplpesslpltlpDITDFEPGPDGESPLARHKDWV  480
            RDW+FSRQRYWGEPIP++H +     ++PES LPL LP   D+ P+  GESPLA   DW+
Sbjct  415  RDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWL  474

Query  481  KTTCPCCGGPATRETDTMPQWAGSSWYFLRYMDPHCKDALASKEALEYWSPVDWYNGGME  540
              T    G  + RET+TMPQWAGSSWY+LRY+DPH  + LA  E L  W PVD Y GG E
Sbjct  475  EVTRE-DGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAE  533

Query  541  HTTLHLLYSRFWHKFLYDIGVVPTAEPYQKRTAHGMILGLNPHSFVNLPAEEQEKLLKEY  600
            H+ LHLLY+RFWHK LYD+GVVPT EP+QK   +GMILG + +       + +  L+   
Sbjct  534  HAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYR-------DSRGALVATD  586

Query  601  GSQKAAEKALEEKYGEMARHPIVKMSKSLGNVINPDEVVDQYGADTMRLYEMFMGDFEQA  660
              +K     ++   GE   ++  KMSKSL NV+NPD+VV+QYGADT+R+YEMFMG ++ +
Sbjct  587  KVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  661  APWQTSAIAGCNRFLDRVWALSDKLVEGEGYRPAMETLMHQTIKKVSADIESLKMNTAIA  720
             +W   ++ G  +FLDRV  L       E    A++ + ++T+K V+ +++ +K NTAIA
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIA  706

Query  721  QLMTLVNAMYDNGGATKAEFETLVQLLNPFAPHMTEELWEKLGHSHDEQLAYYPWPAYEE  780
            QLM +VNA   ++         +VQL+ PFAPH+ EELW+ L  + +E ++Y PWP+Y+E
Sbjct  707  QLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALT-ASGESISYVPWPSYDE  765

Query  781  AKCVEAAVEIAVQVNGKVKARLKVpaditaedaiatakadpavaaaLEGKQLVKEIYVKG  840
            +K VE  VEI VQ++GKVKA+L V+ D++ E+    A A+  V A + GK+++K I V  
Sbjct  766  SKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPN  825

Query  841  RLVNLAAK  848
            +LVN+  K
Sbjct  826  KLVNIVIK  833

640) leuS in NC_010503


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  662 bits (2501),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 402/829 (49%), Positives = 576/829 (70%), Gaps = 58/829 (6%)

Query  2    YNHNKIEKKWQKYWLDNKTFKFVDNPNNPKKFYVLDMFPYPSGKGLHVGHPKGYTATDVI  61
            Y+H  IE KWQ +W DN TFK   ++++PK FY LDMFPYPSG GLHVGHP GYTATD++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPK-FYALDMFPYPSGAGLHVGHPEGYTATDIL  62

Query  62   SRFKRLNGYDVLHPIGWDAFGLPAEQYALETNNHPHTFTQQNIKIFRKQLQMIGFDFDYD  121
            SRFKR +G +VLHP+GWDAFGLPAEQYA++T N+P  FT +NI  F++Q++ +GF +D D
Sbjct  63   SRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWD  122

Query  122  KEVDTTDPQFYQWTQWIFVQLYKHNLAEIQDIDVNWCENLGTVLSNEEVVLNDKNERVSE  181
            +EV+TTDP++Y+WTQWIF +LY   LA   ++ VNW E+LGT ++NEEV+     +  SE
Sbjct  123  REVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVL----PDGTSE  178

Query  182  RGGHPVVRKPMKQWVLKIVDYADKLLDGLNEVEFSESLKSLQRNWIGKSIGTSVQFKIKD  241
            RGG PVVRKPM+QW+LKI  YA++LL++L+EV+ +ES+K +QRNWIGKS G++V FK+KD
Sbjct  179  RGGYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKD  238

Query  242  SLLTLDVFTTRIDTIYGVQYLVVAPEHPILKSITSEQQINVVQSYIEQTKKISDLDRIA-  300
            +   + VFTTR DT++G  Y V+APEH+++ +IT+ +Q + V  Y  Q+   SDL R   
Sbjct  239  TDKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDL  298

Query  301  DTNKTGVFSGAYAINPINQEIIPIWVSDYVLMNFATGAVMGVPAHDERDYAFAKKYALPI  360
              +KTGV +G+YAINP+N   +P+W++DYVL +++TGA+M+VPAHDERD  FAK++ L I
Sbjct  299  AKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDI  358

Query  361  KSVIDTK--QKLPYAGDGLHINSAMINGLNIKQSQNVLNDYLIKNHLGKKVANYKLRNWI  418
             +V++    +  +++ DGLHINS  ++GL+   +   + + L  + +G+    Y+LR+W+
Sbjct  359  IPVLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWL  418

Query  419  FSRQRYWGEPFPVL-FDENNQIKIIE-DLPVLLPNLNEFKPSKTGESPLANAQEWLYVEI  476
            FSRQRYWGEP+P++  ++     + E +LP++LP  ++++PS TGESPLAN  +WL V  
Sbjct  419  FSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTR  478

Query  477  -DGKKYRRETNTMPQWAGSSWYFLAYILKNEDGSYTPLNSEEAKKRFAKWLPVDVYIGGQ  535
             DG K RRETNTMPQWAGSSWY+L YI  ++      L  EE  K+   WLPVD+Y+GG 
Sbjct  479  EDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEK---LADEELLKQ---WLPVDIYVGGA  532

Query  536  EHAVLHLLYSRFWHRFLYDIGVVPTKEPFYKVINQGMILG--------------------  575
            EHAVLHLLY+RFWH+ LYD+GVVPTKEPF K++NQGMILG                    
Sbjct  533  EHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRD  592

Query  576  -------------ENNEKMSKSKGNVINPDDIIASHGADTLRIYEMFMGPLTASLPWNPD  622
                         +   KMSKS  NV+NPDD++   GADTLR+YEMFMGPL AS++W+ +
Sbjct  593  GSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEE  652

Query  623  GLDAMRKWLDRVYRLYHNLSELEVVEDLNKLNEEIIIAYHTLIKNYTKAINEQAFNIAIS  682
            GL++ RK LDRVYRL   ++  E+ E+ +   + +   Y+  +K  T  +++  FN AI+
Sbjct  653  GLEGSRKFLDRVYRL---ITTKEITEENSGALDKV---YNETVKAVTEQVDQMKFNTAIA  706

Query  683  EMMVFVNVLYKNKVINYELLDNFLILLSCYAPHLAEELYS--LNHSESVCLQKMPIYDEq  740
            ++MVFVN   K+  +  +    F+ L++ +APHL+EEL       +ES+     P YDE 
Sbjct  707  QLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDES  766

Query  741  kiiaqnitipiqiNGKLKHTINVLRDTNAEELVNLALACEQVKQEIGDQ  789
            K++ +++ I +QI+GK+K  + V +D + EEL ++ALA E+V+ EI+++
Sbjct  767  KLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGK  815

641) leuS in NC_002162


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  662 bits (2501),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 402/829 (49%), Positives = 576/829 (70%), Gaps = 58/829 (6%)

Query  2    YNHNKIEKKWQKYWLDNKTFKFVDNPNNPKKFYVLDMFPYPSGKGLHVGHPKGYTATDVI  61
            Y+H  IE KWQ +W DN TFK   ++++PK FY LDMFPYPSG GLHVGHP GYTATD++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPK-FYALDMFPYPSGAGLHVGHPEGYTATDIL  62

Query  62   SRFKRLNGYDVLHPIGWDAFGLPAEQYALETNNHPHTFTQQNIKIFRKQLQMIGFDFDYD  121
            SRFKR +G +VLHP+GWDAFGLPAEQYA++T N+P  FT +NI  F++Q++ +GF +D D
Sbjct  63   SRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWD  122

Query  122  KEVDTTDPQFYQWTQWIFVQLYKHNLAEIQDIDVNWCENLGTVLSNEEVVLNDKNERVSE  181
            +EV+TTDP++Y+WTQWIF +LY   LA   ++ VNW E+LGT ++NEEV+     +  SE
Sbjct  123  REVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVL----PDGTSE  178

Query  182  RGGHPVVRKPMKQWVLKIVDYADKLLDGLNEVEFSESLKSLQRNWIGKSIGTSVQFKIKD  241
            RGG PVVRKPM+QW+LKI  YA++LL++L+EV+ +ES+K +QRNWIGKS G++V FK+KD
Sbjct  179  RGGYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKD  238

Query  242  SLLTLDVFTTRIDTIYGVQYLVVAPEHPILKSITSEQQINVVQSYIEQTKKISDLDRIA-  300
            +   + VFTTR DT++G  Y V+APEH+++ +IT+ +Q + V  Y  Q+   SDL R   
Sbjct  239  TDKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDL  298

Query  301  DTNKTGVFSGAYAINPINQEIIPIWVSDYVLMNFATGAVMGVPAHDERDYAFAKKYALPI  360
              +KTGV +G+YAINP+N   +P+W++DYVL +++TGA+M+VPAHDERD  FAK++ L I
Sbjct  299  AKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDI  358

Query  361  KSVIDTK--QKLPYAGDGLHINSAMINGLNIKQSQNVLNDYLIKNHLGKKVANYKLRNWI  418
             +V++    +  +++ DGLHINS  ++GL+   +   + + L  + +G+    Y+LR+W+
Sbjct  359  IPVLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWL  418

Query  419  FSRQRYWGEPFPVL-FDENNQIKIIE-DLPVLLPNLNEFKPSKTGESPLANAQEWLYVEI  476
            FSRQRYWGEP+P++  ++     + E +LP++LP  ++++PS TGESPLAN  +WL V  
Sbjct  419  FSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTR  478

Query  477  -DGKKYRRETNTMPQWAGSSWYFLAYILKNEDGSYTPLNSEEAKKRFAKWLPVDVYIGGQ  535
             DG K RRETNTMPQWAGSSWY+L YI  ++      L  EE  K+   WLPVD+Y+GG 
Sbjct  479  EDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEK---LADEELLKQ---WLPVDIYVGGA  532

Query  536  EHAVLHLLYSRFWHRFLYDIGVVPTKEPFYKVINQGMILG--------------------  575
            EHAVLHLLY+RFWH+ LYD+GVVPTKEPF K++NQGMILG                    
Sbjct  533  EHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRD  592

Query  576  -------------ENNEKMSKSKGNVINPDDIIASHGADTLRIYEMFMGPLTASLPWNPD  622
                         +   KMSKS  NV+NPDD++   GADTLR+YEMFMGPL AS++W+ +
Sbjct  593  GSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEE  652

Query  623  GLDAMRKWLDRVYRLYHNLSELEVVEDLNKLNEEIIIAYHTLIKNYTKAINEQAFNIAIS  682
            GL++ RK LDRVYRL   ++  E+ E+ +   + +   Y+  +K  T  +++  FN AI+
Sbjct  653  GLEGSRKFLDRVYRL---ITTKEITEENSGALDKV---YNETVKAVTEQVDQMKFNTAIA  706

Query  683  EMMVFVNVLYKNKVINYELLDNFLILLSCYAPHLAEELYS--LNHSESVCLQKMPIYDEq  740
            ++MVFVN   K+  +  +    F+ L++ +APHL+EEL       +ES+     P YDE 
Sbjct  707  QLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDES  766

Query  741  kiiaqnitipiqiNGKLKHTINVLRDTNAEELVNLALACEQVKQEIGDQ  789
            K++ +++ I +QI+GK+K  + V +D + EEL ++ALA E+V+ EI+++
Sbjct  767  KLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGK  815

642) leuS in NC_018664


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  661 bits (2498),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 420/835 (51%), Positives = 581/835 (70%), Gaps = 41/835 (4%)

Query  4    YNPKQIEKKWQDIWDEKGTFHALEDKTKPKFYALIEFPYPSGQGLHVGHPRPYTALDIVS  63
            Y+   IE KWQ +W ++ TF +  D +KPKFYAL  FPYPSG GLHVGHP  YTA DI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RKRRMQGYNVLYPMGWDAFGLPTENYAIKNKIHPKIVTEQNVSRFKSQLKSLGLSFDWSR  123
            R +R QG NVL PMGWDAFGLP+E+YA+    +P   T +N++ FK Q+++LG+S+DW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EINTTHPEYYKWTQWIFLKLFEKGLAYKKEASINWCPDCKVGLANEEVV-NGACERCSTE  182
            E+NTT+P+YYKWTQWIF KL+EKGLAY  E ++NW  +   ++ANEEV+ +G+ ER +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VTRKVKTQWMLKITEYAERLIKDLDLVDYIDRVKIQQKNWIGKSEGMEVDFEVSGGEK-L  241
            V RK   QWMLKIT YAERL+ DL+ VD  + +K  Q+NWIGKS G +V F V + +K +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  KIYTTRPDTLYGVTYMVISPEHPVIETLKDKINNMDKIEEYQEFASKKSDFERTELAKDK  301
             ++TTRPDTL+G TY V++PEH++++++    ++ + + +Y+  AS KSD+ RT+LAK+K
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTS-DQAEAVADYKRQASLKSDLARTDLAKEK  302

Query  302  TGVEIEGIKAINPATGKEIPIWISDYVLMSYGTGAIMAVPGHDSRDWEFAKKFGLPIVEV  361
            TGV   G  AINP  GKE+P+WI+DYVL SYGTGAIMAVP+HD RDWEFAK+F L I+ V
Sbjct  303  TGV-WTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  362  ISGGNVEEAPFTETENGTLINSDIIDGLSVNEAKEKIANYLEEKGIGQRKTNYKLRDWVF  421
            + GGNVEEA+F  TE+G  INSD++DGL    A  K+ + LE  G+G+ +  Y+LRDW+F
Sbjct  362  LEGGNVEEAAF--TEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLF  419

Query  422  SRQRYWGEPIPMVHCDKCGIvplpeselpltlpevesYEPTDNGESPLAKISDWINTTCP  481
            SRQRYWGEPIP++H +     ++PESELPL LP      P++ GESPLA+++DW++ T  
Sbjct  420  SRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRE  479

Query  482  KCGGSAKRETDTMPQWAGSSWYFLRYTDPHNDKELASKENLDYWVPVDWYNGGMEHTTLH  541
              G  ++RET+TMPQWAGSSWY+LRY DPHN   LA  E L  W+PVD Y GG EH+ LH
Sbjct  480  D-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLH  538

Query  542  LLYSRFWHKFLFDYGIVPTPEPYQKRTSHGMILGNN------------------------  577
            LLY+RFWHK L+D G+VPT EP+QK  ++GMILG +                        
Sbjct  539  LLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHV  598

Query  578  ---------NEKMSKSRGNVINPDEVVDEHGADTLRTYEMFIGDFEKSVSWSDNGVKGCR  628
                       KMSKS  NV+NPD+VV++ GADTLR YEMF+G ++ S++WS++G+ G R
Sbjct  599  ETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSR  658

Query  629  RFLERVWKLQDILVEGEEYSKELETSMHKTIKKVTQDFEAMKFNTAIASLMSLLNEFNNI  688
            +FL+RV +L       EE S  L+   + T+K VT++ + MKFNTAIA LM ++N  N+ 
Sbjct  659  KFLDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKE  718

Query  689  GKVNKAEFKTFITLLNPSAPHITEELWEIVGYSG-MLNETEWPKWDDSKTVDDTIEMAVQ  747
            +K+     K F+ L+ P APH+ EELW+ +  SG  ++   WP  D+SK V++ +E+ VQ
Sbjct  719  DKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQ  778

Query  748  INGKVRGKILVPKDATAELAkskvledeklsellkdkNIVKEIYVAGRIYNIVVK  802
            I+GKV++K++V+KD + E  +   L +EK+   + +K+I+K I V+ ++ NIV+K
Sbjct  779  IKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

643) leuS in NC_013171


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  658 bits (2488),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 409/814 (51%), Positives = 567/814 (70%), Gaps = 38/814 (4%)

Query  22   TFKSEIDNNKKKFYPLVEFPYPSGQGLHVGHPRPYTALDVVARKRRLEGENVMYPMGWDA  81
            TFK+  D +K KFY+L  FPYPSG GLHVGHP  YTA D+++R +R +G+NV+ PMGWDA
Sbjct  22   TFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSRFKRAQGHNVLHPMGWDA  81

Query  82   FGLPTENYAIKNKIHPAKVTEDNIAHFKEQMKSIGFSFDWDREVNTTDPDYYKWSQWIFI  141
            FGLP+E+YA+    +PA  T +NIA+FK Q++++GFS+DWDREVNTTDP+YYKW+QWIF 
Sbjct  82   FGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFT  141

Query  142  QMYKHGLAYKNEMSVNWCPSCQVGLANEEVV-DGKCERCGTEVVHKMKNQWMLKITEYAD  200
            ++Y  GLAY  E++VNW      ++ANEEV+ DG  ER G  VV+K   QWMLKIT YA+
Sbjct  142  KLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAE  201

Query  201  RLIDDLEEVDFEERIKASQINWIGRSHGCDVDFKIKDLDEKLTVYTTRPDTIFGVSYMVV  260
            RL++DLEEVD  E IK  Q NWIG+S G +V FK+KD D  +TV+TTRPDT+FG +Y V+
Sbjct  202  RLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVL  261

Query  261  SPEHPILDKYKERIKNFTEIEAYQEEAKKKSDFERSELNKDKTGVMIDGISAINPLNDKE  320
            +PEH+++D      +    +  Y+ +A  KSD+ R++L K+KTGV   G  AINP+N+KE
Sbjct  262  APEHALVDAITTSDQA-EAVADYKRQASLKSDLARTDLAKEKTGVWT-GSYAINPVNGKE  319

Query  321  IPIWVSDYVLMTYGTGAIMAVPAHDSRDFEFAKKFDMPIIPVYDTGEELPTTDINKGEAI  380
            +P+W++DYVL +YGTGAIMAVPAHD RD EFAK+F++ IIPV + G+   ++  + G  I
Sbjct  320  MPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEAAFTEDGLHI  379

Query  381  NSDFLNGLSASDAKKKAIEYVEEKGLGKAKTNFKLRDWVFSRQRYWGEPIPMIYCEEHGW  440
            NSDFL+GL  + A  K +E +E  G+G+ +  ++LRDW+FSRQRYWGEPIP+I  E+   
Sbjct  380  NSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTS  439

Query  441  vpvpeeelpvklpdvpSYEPTATGESPLSEIEEFVNTTCPICGKPAKRETDTMPQWAGSS  500
             +VPE ELP+ LP      P++TGESPL+++ + ++ T     K ++RET+TMPQWAGSS
Sbjct  440  TAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK-GRRETNTMPQWAGSS  498

Query  501  WYYLRYMDPNNKEAIASKEALDYYSPVDWYNGGMEHTTLHLLYSRFWHKFLYDIGVVPTK  560
            WYYLRY+DP+N E +A  E L    PVD Y GG EH+ LHLLY+RFWHK LYD+GVVPTK
Sbjct  499  WYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTK  558

Query  561  EPYKKRTSHGMILGS---------------------------------DHQKMSKSRGNV  587
            EP++K  ++GMILG+                                    KMSKS  NV
Sbjct  559  EPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNV  618

Query  588  INPDDIVRDYGADTLRCYEMFMGDFSSMAIWSDEGVRGCRKYLERVFNLTDLVVDGEEYS  647
            +NPDD+V +YGADTLR YEMFMG + +   WS+EG+ G RK+L+RV+ L       EE S
Sbjct  619  VNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITEENS  678

Query  648  KDLEVVINQTIKKVSEDYENLKFNTAIAKLMTLLNEMKSLGKITKKDFKTYITLLNPVAP  707
              L+ V N+T+K V+E+ +++KFNTAIA+LM ++N  +  +K+     K ++ L+ P AP
Sbjct  679  GALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAP  738

Query  708  HMTEELWEMMSYEGE-LNQTTWPSYDEDKLSFDSFEMPVQINGKVRATVMMDKDASKEDA  766
            H+ EELW+ ++  GE ++   WPSYDE KL  +  E+ VQI+GKV+A +++ KD S+E+ 
Sbjct  739  HLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREEL  798

Query  767  IKSAQEDNNIKSYIEGKEIRKIIYVPGKILNIVV  800
               A  ++++++ I GK+I K+I VP K++NIV+
Sbjct  799  QEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

644) leuS in NC_011025


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  658 bits (2487),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 414/845 (49%), Positives = 588/845 (70%), Gaps = 57/845 (6%)

Query  2    YNHREIEKKWQKFWEQNHSFKTTEKHNK-KAYILDMFPYPSGMGMHVGHLEGYTATDIVS  60
            Y+H  IE KWQ FW +NH+FKT    +K K Y LDMFPYPSG G+HVGH EGYTATDI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  61   RFKRLNGFDVLHPIGWDAFGLPAEQYALNTGNHPAPFTIKNIDNFRRQLKAMGFSYDYDK  120
            RFKR +G +VLHP+GWDAFGLPAEQYA++TGN+PA FT  NI NF+RQ++A+GFSYD D+
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  121  EINTTDPKFYYWTQWIFKELYKNGLASIEEVDVNWCEGLGTVLANEEIVEKNGIKVSERG  180
            E+NTTDP++Y WTQWIF  LY +GLA   EV VNW E LGT +ANEE++       SERG
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDG---TSERG  180

Query  181  SFPVVKKPMRQWVLKISNYADKLLEGLDSLDWPESLKALQRNWIGKSNGHIVSWKL-EKN  239
            ++PVV+KPMRQW+LKI+ YA++LLE+L+ +DWPES+K +QRNWIGKS G  V+ K+ + +
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  240  RIIKTFTTRLDTIYGVSALVLSPEHPLVDLITTSSQKFLVDKYLCASKQKSELERTQLQK  299
            + +  FTTR DT++G +  VL+PEH+LVD ITTS Q   V  Y   +  KS+L RT+L K
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  300  EKSGVFTGSYALHPLTNKKIPIWISDYVLMSHGTGAVMSVPAHDERDFQFATRYNLEIIP  359
            EK+GV TGSYA++P+  K +P+WI+DYVL S GTGA+M+VPAHDERD +FA ++NL+IIP
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  360  VIKSDD-NVLPYTGNGVHFNSDIankkdnanatkaIFTKLSSLNSAKEHVSYKLRDWIFS  418
            V+ +++ +  ++T +G+H+NSD+ +  D+A+A   +   L +   ++E+V+Y+LRDW+FS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  419  RQRYWGEPFPILF--DENNDIYLVKEL-VSLPETNNIKPSGSTEGPLANIKEWMNV-KVN  474
            RQRYWGEP+PI+   D  +      EL + LP T++I+PSG+ E+PLAN+ +W++V + +
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  475  GKNFRRDSNVMPQWAGSSWYYLAYILKNSDGTYAPLDSSEAKKRFENWLPVDLYIGGQEH  534
            G + RR++N MPQWAGSSWYYL YI  ++      L   E  K+   WLPVD+Y+GG EH
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEK---LADEELLKQ---WLPVDIYVGGAEH  534

Query  535  AVLHLLYARFWHRFLFDIGIVPTKEPFTKLINQGLILGP---------------------  573
            AVLHLLYARFWH+ L+D+G+VPTKEPF KL+NQG+ILG                      
Sbjct  535  AVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGS  594

Query  574  ------------DGQKMSKSLGNVINPDDLIQTHGADALRIFEMFMGPLTDSKPWNTSSL  621
                           KMSKSL NV+NPDD+++  GAD+LR++EMFMGPL  S +W+  +L
Sbjct  595  FFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGL  654

Query  622  DGIRKWLDRLYSNFNYFVKNQKFSLSEKNDQLESNLNILIKEATDAIEKYKFNIAISKLM  681
            +G RK LDR+Y     ++  + ++  E+++ L+   N  +K  T+ +++ KFN AI++LM
Sbjct  655  EGSRKFLDRVYR----LITTKEIT-EENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLM  709

Query  682  VFSNYLGTLKVLPSTLPLKNFAIIFSVFAPHLAEELLAMINEAPVEMQ--SWPFCEESKI  739
            VF N       L S  + K F  +++ FAPHL+EEL   +  +   +   +WP  +ESK+
Sbjct  710  VFVNAANKEDKLFSDYA-KGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKL  768

Query  740  IAQNPIIGVQINGKVRGQIEIMPSWDQEAIVKNASAQSQIAKWLENKKIFKVIYVENKIL  799
            + ++  I VQI+GKV++++ +     +E +   A A+ ++   +  K I+KVI V NK++
Sbjct  769  VENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLV  828

Query  800  NLIVK  804
            N+++K
Sbjct  829  NIVIK  833

645) CC1_19310 in NC_021009


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  657 bits (2485),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 391/834 (47%), Positives = 568/834 (69%), Gaps = 41/834 (4%)

Query  3    YDFAKIESKWQKKWADADLFAAKDNSDKPKFYGLVEFPYPSGAGMHVGHIKAYSGLEVVS  62
            YD + IE+KWQ  WAD + F +  ++ KPKFY+L  FPYPSGAG+HVGH  +Y++ +++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RKRRMQGYNVLFPIGFDAFGLPAENYAIKTNTHPRIVTDQNIERFSNQMKRMGFSFDWDR  122
            R +R QG NVL P+G DAFGLPAE+YA+ T  +P   T +NI  F  Q++ +GFS+DWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  VIDTTQEDYYKWTQWIFLKLFEKGLAYRDKTLVNYCPSCKVVLSNEDS-QGGKCDICHSD  181
             ++TT+ +YYKWTQWIF KL+EKGLAY     VN        ++NE+   +G  +     
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VIQKSKEVWYLRITKYADKLLEGLNEVDYPDNIKQQQQHWIGKSTGAFVNFKLDNEQESL  241
            V++K+   W L+IT YA++LLE+L+EVD P++IK+ Q++WIGKSTGA V FK+ + +  +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  RVYTTRPDTLFGVTFMVIAPEHPLIDKYADQIRNMDQIEAYREECAKKSEFERIEINKDK  301
             V+TTRPDTLFG T+ V+APEH+L+D  +   +  + +  Y+ + + KS++ R ++ K+K
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQA-EAVADYKRQASLKSDLARTDLAKEK  302

Query  302  TGVKIDGLMAVNPVSGKKVPLFIADYVMMGYGTGAIMAVPAHDQRDYDFAKKFGEEIIPV  361
            TGV  ++  A+NPV+GK +P+ IADYV+ +YGTGAIMAVPAHD+RD +FAK+F  +IIPV
Sbjct  303  TGVWTGSY-AINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  362  IKGGDIDTEAYTGDGEMINSDFLNGYTNKKDSIEKMIEVLEEKGIGEKGVQYKMKDWAFN  421
            + GG+++  A+T DG  INSDFL+G  +K  +I KM+E LE  G+G+  V Y+++DW F+
Sbjct  362  LEGGNVEEAAFTEDGLHINSDFLDGL-DKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  422  RQRYWGEPIPIVHCPKCGMVGVPYEELPLRLPKVEHFQPGEDGESPLAKIDSFVNCKCPK  481
            RQRYWGEPIPI+H       +VP  ELPL LP   +++P+  GESPLA++   ++     
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  482  CGGDAKRETDTMPQWAGSSWYFLRYIDPHNTEALADPNKLKYWMPVDWYNGGMEHVTRHM  541
             G  ++RET+TMPQWAGSSWY+LRYIDPHNTE LAD + LK W+PVD Y GG EH   H+
Sbjct  481  -GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHL  539

Query  542  IYSRFWHRFLYDIGVVNTPEPYAKRSAQGLILGP--------------------------  575
            +Y+RFWH+ LYD+GVV T EP+ K   QG+ILG                           
Sbjct  540  LYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVE  599

Query  576  -------DGTKMSKSKGNVVDPLDVADKYGADTLRTYILFMGDYGASTPWNENSVRGCKR  628
                     +KMSKS  NVV+P DV ++YGADTLR Y +FMG  +AS +W+E+++ G ++
Sbjct  600  TGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRK  659

Query  629  FLDRVYRIFEK--VTDENLHSLDNPLHKAIKKVSDDIEDMKYNTAIATLMALLNDFESAT  686
            FLDRVYR++    +T+EN  +LD+  + ++K V++++++MK+NTAIA LM ++N  +   
Sbjct  660  FLDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKED  719

Query  687  TVGKEQYVTFLKLLSPFAPHITEELWEMLGGEG-FLSVSEWPVYDESKMVDETVEIGVQV  745
             +  +    F++L++PFAPH+ EELW+ L + G  +S   WP YDESK+V++ VEI VQ+
Sbjct  720  KLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQI  779

Query  746  NGKPKDAVELSLDDDEETAVAKAMALPKIANITAGKNIVKVIYKPGKILNLIVK  799
            +GK K  + ++ D   E     A+A  K+    AGK+I+KVI  P K++N+++K
Sbjct  780  KGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

646) ELI_3047 in NC_014624


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  653 bits (2470),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 397/841 (48%), Positives = 574/841 (69%), Gaps = 46/841 (5%)

Query  1    MKIYDHHKIEKKWQKYWEDHDTFKIEQNSDKEKFYGLVEFPYPSGAGLHVGHVRAYTSLE  60
            M +YDH  IE KWQ +W D++TFK   ++ K KFY+L  FPYPSGAGLHVGH  +YT+ +
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   IISRKRRMEGFNVLFPIGWDAFGLPTENYAIKTGRHPREVTDENIKVFTQQLKSIGYSFD  120
            I+SR +R +G NVL P+GWDAFGLP+E+YA+ TG +P E T ENI  F +Q++++G+S+D
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WDCEIDTTDPNYFKWTQWIFLQLFKHGLVYRDRTYVNFCSGCKVVLANED-FREGKCSIC  179
            WD E++TTDPNY+KWTQWIF +L+  GL Y     VN        +ANE+ + +G     
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  180  GSEVVQLEKDVWFLKIREYAEKLLAGLDDVDYLPRIRLEQENWIGKSIGAEVDFDIAGAD  239
            G  VV+     W LKI  YAE+LL +L++VD    I+  Q NWIGKS GA+V F + ++D
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  240  QKLRVFTTRPDTLFGVTFMVIAPEHPLIEEMKDRITNMDAIVDYQEAAKRKTEFERVQLA  299
            + + VFTTRPDTLFG T+ V+APEH+L++ +     + +A+ DY+  A  K+++ R +LA
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTS-DQAEAVADYKRQASLKSDLARTDLA  299

Query  300  KEKTGVMIEGIRGINPLSGEEVPIFIADYVMMGYGTGAIMAVPGHDTRDWEFAKKFDLPI  359
            KEKTGV   +  +INP++G E+P+ IADYV+ +YGTGAIMAVP+HD RDWEFAK+F+L I
Sbjct  300  KEKTGVWTGSY-AINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDI  358

Query  360  IEVIKGGDVSVEAYTDTASGEMVNSGFLNGMEVKEAIAKTIEYLEEKGLGKKTINYKMKD  419
            I V+ GG+V   A+T+   G  +NS+FL+G++   AIAK +E LE  G+G+  + Y+++D
Sbjct  359  IPVLEGGNVEEAAFTE--DGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WAFNRQRYWGEPIPIVHCPKCGMVPVPEDQLPLELPKVKSYEPTDTGESPLAGIPEWVNT  479
            W F+RQRYWGEPIPI+H       +VPE +LPL LP  K   P++TGESPLA + +W++ 
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  480  TCPHCGGPAKRETDTMPQWAGSSWYFLRYFDNKNDQALADYDKMKYWMPVDWYNGGMEHV  539
            T  + G  ++RET+TMPQWAGSSWY+LRY+D  N + LAD + +K W+PVD Y GG EH 
Sbjct  477  TRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  540  TRHLLYSRFWHKFLYDIGVVPTAEPYKKRTMQGLILGS----------------------  577
              HLLY+RFWHK LYD+GVVPT EP++K   QG+ILG+                      
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSF  595

Query  578  -----------DGEKMSKSKGNVVNPNDIIDEYGADTLRTYVMFIGDYEKPAPWSENGTK  626
                          KMSKS  NVVNP+D++++YGADTLR Y MF+G  + + +WSE+G  
Sbjct  596  FHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLE  655

Query  627  GAKRYLDRVWKL---QEIVTDETGYSQELESMMHKTIKKVNSDYEEMKFNTAIAALMTLL  683
            G++++LDRV +L   +EI  +++G    L+ + + T+K V  + ++MKFNTAIA LM ++
Sbjct  656  GSRKFLDRVYRLITTKEITEENSG---ALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFV  712

Query  684  NEFNSVGKVTKDEFKTYLQLLYPVAPHITEELWE-IAGLEGCLHDSPWPVYDEAKTVDDV  742
            N  N  +K+  D  K ++QL+ P APH+ EELW+ +++    +   PWP YDE+K V++ 
Sbjct  713  NAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVEND  772

Query  743  IEMAVQINGKVRGKISLPadadkeaakaiaLEHENIRSYVEGKNIVKEIFVPGKIFNLVV  802
            +E+ VQI+GKV++K+ ++ D  +E  + +AL +E++++ + GK+I+K I VP K+ N+V+
Sbjct  773  VEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

Query  803  K  803
            K
Sbjct  833  K  833

647) Clole_1316 in NC_015275


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  652 bits (2464),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 408/838 (49%), Positives = 574/838 (69%), Gaps = 50/838 (5%)

Query  3    YNHKEIEQKWRKHW-EEHPVNVETEGKKP-YYCLDMFPYPSGNGLHVGHWRGYVLSDVWS  60
            Y+H  IE KW+  W ++H  +  T++ KP +Y LDMFPYPSG GLHVGH  GY  +D+ S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  61   RYKILQNHYVLHPMGWDAFGLPAENYAIQKKVHPAIATAENVANFKRQLHDISAVYDWDK  120
            R+K  Q H VLHPMGWDAFGLPAE+YA++   +PA  TAEN+ANFKRQ++ ++  YDWD+
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  121  EVNTTDPEFYKWTQWIFLKMFENGLAYEKEMPINWCPSCKTGLANEEV-KEGCCDRCGST  179
            EVNTTDP++YKWTQWIF K++E+GLAYE E+P+NW     T++ANEEV  +G  +R G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  180  VTKKNLRQWMLKITNYAERLLNDLDGLDWPEKVKKMQADWIGKSYGAEIDFEIEGTDEKI  239
            V +K +RQWMLKIT YAERLL+DL+ +DWPE +K MQ +WIGKS GA++ F + +TD  +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  240  KVFTTRPDTLYGASFMVMAPEHAKVMVLTTESQKAEVEKYVFDASTKSSVDRMA-DKEKT  298
             VFTTRPDTL+GA++ V+APEHA V  +TT  Q   V  Y  +AS KS + R    KEKT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  299  GVFLGRYAINPLNGAKIPVWISDYVLADYGTGAIMCVPAHddrdfafakkfdLPIIQVIS  358
            GV  G YAINP+NG  +PVWI+DYVLA YGTGAIM VPAHD+RD  FAK+F+L II V+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  359  KSGeeeelteayteaGVMINSGDFNGMPSEEAKKAIPEFLETQNIGKKTTNYKLRDWVFS  418
             +        A+TE G+ INS+ ++G+    A   + E LE++ +G+    Y+LRDW+FS
Sbjct  364  GGN---VEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  419  RQRYWGEPIPVVHCDCCGIVGVKEEDLPIRLPDVESYEPTGTGESPLAAIDEWVNTTCPK  478
            RQRYWGEPIP++H +     +V E +LP+ LP      P+GTGESPLA + +W++ T   
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  479  CGGPAKRETNTMPQWAGSSWYFLRYPNPHNDEELISKEDMKKWLPVDMYVGGIEHAVLHL  538
             G  ++RETNTMPQWAGSSWY+LRY +PHN E L   E +K+WLPVD+YVGG EHAVLHL
Sbjct  481  -GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHL  539

Query  539  LYARFYTKFLFDIGVVDFEEPFKRLFNQGMV-----------------------------  569
            LYARF  K L+D+GVV   EPF++LFNQGM+                             
Sbjct  540  LYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVE  599

Query  570  -----TKAGAKMSKSKGNVVSPDELVEKYGCDSLRMYELFIGPPELDSEWDDRGIEGVYR  624
                  +A AKMSKS  NVV+PD++VE+YG D+LR+YE+F+GP +    W + G+EG  +
Sbjct  600  TGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRK  659

Query  625  FLNKVWKLVDENTAVAETKD-MERIRHKLIRDITVRMENFNLNTVVSGFMQYTNELLDLQ  683
            FL++V +L+  +    E  + ++++ +  ++ +T ++++ ++NT ++ +M + N      
Sbjct  660  FLDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNA----A  715

Query  684  KKQGGLANETLKALVILLAPFVPHISEELWAKVGGSGSVFE-NTWPTYDEEKMKEDEVEI  742
            +K++ L ++  K++V L+APF PH++EELW  + +SG  +    WP+YDE K+ E++VEI
Sbjct  716  NKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEI  775

Query  743  VVQITGKIAARMMISPEASQEE--AIKKAKELIADKLAGKTVVKEIYVPGRIVNLVAK  798
            VVQI GK+ A+++++ + S+EE   +  A+E +   +AGK ++K I VP ++VN+V K
Sbjct  776  VVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

648) CK5_25320 in NC_021022


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  652 bits (2463),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 390/835 (47%), Positives = 566/835 (68%), Gaps = 42/835 (5%)

Query  3    YMFKKIEPKWQAKWEESKVFEAKDNSDKPKFYGLVEFPYPSGAGMHVGHIKAYSSLEVIS  62
            Y    IEPKWQA W ++  F +  ++ KPKFY+L  FPYPSGAG+HVGH  +Y++ +++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RKRRMEGYNVLFPIGFDAFGLPTENYAVKTGTHPRIITDENIKKFSNQLKKVGFSFDWNR  122
            R +R +G NVL P+G DAFGLP+E+YA+ TG +P  +T ENI +F  Q++ +GFS+DW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  VIDTTDEDYYKWTQWIFLKMFEKGLVFRDRTLVNYCPHCKVVLSNEDS-QGGKCDICHSE  181
             ++TTD +YYKWTQWIF K++EKGL +     VN   +    ++NE+   +G  +     
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VVQKSKDVWYLRITQYADKLLEGLKDVDYPDNVKQQQVHWIGKSKGAFVNFDIDGIDEKL  241
            VV+K+   W L+IT YA++LLE+L +VD P+++K+ Q +WIGKS GA V F + + D  +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  EIYTTRPDTLFGVTFMVIAPEHPIIDKYKDKVTNMDEITAYRNECAKKTEFERTQLVKDK  301
             ++TTRPDTLFG T+ V+APEH+++D       + + ++ Y+ + + K+++ RT+L K+K
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTS-DQAEAVADYKRQASLKSDLARTDLAKEK  302

Query  302  TGVCIQGLEGINPVNGKKIPIYIADYVMMGYGTGAIMAVPAHDQRDYDFAKKFGIDIIEV  361
            TGV   +  +INPVNGK +P+ IADYV+ +YGTGAIMAVPAHD+RD +FAK+F +DII V
Sbjct  303  TGVWTGSY-AINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  362  IKGGDISKEAYTGDGEMINSDFLNGYTKKKDSIERMLEELEKKGIGKAGVQYKMKDWAFN  421
            + GG++   A+T DG  INSDFL+G   K  +I +M+E LE  G+G+  V Y+++DW F+
Sbjct  362  LEGGNVEEAAFTEDGLHINSDFLDGL-DKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  422  RQRYWGEPIPLIHCPNCGVVAVPEEELPLRLPDVKDFEPGEDGQSPLAKIDSFVNCTCPK  481
            RQRYWGEPIP+IH  +    AVPE ELPL LP  KD+ P+  G+SPLA++   ++ T   
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  482  CGAAAKRETDTMPQWAGSSWYFLRYTDPHNTQALADMDKLKYWMPVDWYNGGMEHVTRHM  541
             G  ++RET+TMPQWAGSSWY+LRY DPHNT+ LAD + LK W+PVD Y GG EH   H+
Sbjct  481  -GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHL  539

Query  542  IYSRFWHHFLYDLGVVNTPEPYAKRSIQGLILGP--------------------------  575
            +Y+RFWH  LYDLGVV T EP+ K   QG+ILG                           
Sbjct  540  LYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVE  599

Query  576  -------DGDKMSKSKGNVVDPLDIVEEYGADTLRTYVLFMGDYGAATPWSDSSVKGCKK  628
                      KMSKS  NVV+P D+VE+YGADTLR Y +FMG  +A+ +WS+ ++ G +K
Sbjct  600  TGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRK  659

Query  629  FLDRVAGL--TDILSEEPVSDELEMKIHRTIKKVSSDIESLKFNTAIASLMTLINEITAE  686
            FLDRV  L  T  ++EE  S+ L+   + T+K V+ +++ +KFNTAIA LM ++N    E
Sbjct  660  FLDRVYRLITTKEITEEN-SGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKE  718

Query  687  GHIGKEDLGIFIKLLSPFAPHLCEEIWEFLGGEG-LLAVAPWPVHDEGKTVSKTVEIGVQ  745
            + +  +    F++L++PFAPHL EE+W+ L + G  ++  PWP  DE+K V + VEI VQ
Sbjct  719  DKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQ  778

Query  746  VNGKVRGTIVIPNGCEKEKAFEIAKADERIASFLEGKNLIKEIYVPNKIVNFVAK  800
            ++GKV++ +V++++  +E   E+A A+E++ + + GK++IK I VPNK+VN+V K
Sbjct  779  IKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

649) leuS in NC_022441


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  650 bits (2456),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 417/839 (50%), Positives = 593/839 (71%), Gaps = 31/839 (3%)

Query  3    YDPSLIEKKWQKFWKENKTFRAIEDTSKEKYYVLDMFPYPSGAGLHVGHLIGYTATDILA  62
            YD + IE KWQ FW +N TF++  D+SK K+Y LDMFPYPSGAGLHVGH  GYTATDIL+
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRARGFSVLHPMGWDSFGLPAEQYAIRTGTHPKLTTKKNIENFKVQLSAMGFSYDEDR  122
            R+KRA+G +VLHPMGWD+FGLPAEQYA+ TG +P   T  NI NFK Q++A+GFSYD DR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EFATSDAEYYHWTQKLFLYLYQQGLAYMADMAVNYCPQLGTVLSNEEV-EDGLSIEGGYP  181
            E  T+D++YY WTQ +F  LY++GLAY A+++VN   +LGT ++NEEV  DG S  GGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRMLRQWILKITAYADKLLEGLDDLDWPESVKQLQRNWIGKSKGALIRF-FMDSGENL  240
            V R+ +RQW+LKITAYA++LLE+L+++DWPES+K++QRNWIGKS GA + F   D++ ++
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  EVFSTRPDTLCGVSFLVLAPEHPLVEKIVLPEKKAEVESYVQEVLGRSERDRISTVKRKS  300
             VF+TRPDTL G ++ VLAPEH+LV+ I  +++   V  Y ++   +S+  R    K K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  301  GVFTGRYAKHPITHEEIPIWIADYVILGYGSGVVMGVPGHDERDREFAETFSLPIHEVIN  360
            GV TG YA +P+   E+P+WIADYV+ +YG+G +M+VP+HDERD+EFA  F+L I  V++
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  361  S----------EGYCIHSSFGEFCLDGLCGQEAREYVIRYLERLGLGEAKVMYKLRDWLF  410
            +          +G  I+S F    LDGL    A   ++  LE  G+G+ +V Y+LRDWLF
Sbjct  364  GGNVEEAAFTEDGLHINSDF----LDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLF  419

Query  411  SRQRYWGEPIPIVHFEDGTSRpleddelpllppdiedYRPEGFGLGPLAKAKDWVDIIDS  470
            SRQRYWGEPIPI+H EDGTS ++ + ELPL+ P   D RP G G +PLA+  DW+++   
Sbjct  420  SRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT-R  478

Query  471  KTGKKGRRETHTMPQWAGSCWYYLRFCDAHNLLSPWSKEKESYWMPVDLYIGGAEHAVLH  530
              G KGRRET+TMPQWAGS WYYLR+ D+HN       E    W+PVD+Y+GGAEHAVLH
Sbjct  479  EDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLH  538

Query  531  LLYARFWHRVFYDGGLVSTKEPFQKLVNQGLVLATSYRLPGKGYVYPEEVHEENGV-WKT  589
            LLYARFWH+V+YD G+V+TKEPFQKL NQG++L+TSYR +  + V  + V+  +G     
Sbjct  539  LLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHV  598

Query  590  ASGEPVLVRQEKMSKSKLNGVDPQTLIEEYGADALRMYAMFSGPLDKNKLWSNQGVAGCR  649
             +GE +     KMSKS  N V+P+ ++E+YGAD+LR+Y MF GPLD +  WS++G+ G R
Sbjct  599  ETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSR  658

Query  650  RFLNRFFELVTSSKVQDVDDHQGLALAYK-LVHRVTEDIEKLSLNTIPSNFMEFLNHFLK  708
            +FL+R + L+T+  + + ++  +L   Y+  V  VTE+++++ +NT  +++M F+N   K
Sbjct  659  KFLDRVYRLITTKEITE-ENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANK  717

Query  709  ----LPVYSKaalalavrvlaPIAPHISEELWVYL-GNDAGIDRALWPQTEERYLQDSLV  763
                ++ Y+K      V+++AP+APH++EELW  L +++ +I    WP  +E  L ++ V
Sbjct  718  EDKLFSDYAK----GFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDV  773

Query  764  TMVVQVNGKLRGCLKLDKDLPKDEV--LLLARKAVDKYLQDVLIKKEIFVPNKLVNFVV  820
             +VVQ++GK+++ L + KDL+++E+  + LA   V+  + +  I K I VPNKLVN+V+
Sbjct  774  EIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

650) leuS in NC_022439


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  650 bits (2457),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 418/839 (50%), Positives = 593/839 (71%), Gaps = 31/839 (3%)

Query  3    YDPSLIEKKWQKFWKENKTFRAIEDTSKEKYYVLDMFPYPSGAGLHVGHLIGYTATDILA  62
            YD + IE KWQ FW +N TF++  D+SK K+Y LDMFPYPSGAGLHVGH  GYTATDIL+
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRARGFSVLHPMGWDSFGLPAEQYAIRTGTHPKLTTKKNIENFKVQLSAMGFSYDEDR  122
            R+KRA+G +VLHPMGWD+FGLPAEQYA+ TG +P   T  NI NFK Q++A+GFSYD DR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EFATSDAEYYHWTQKLFLYLYQQGLAYMADMAVNYCPQLGTVLSNEEV-EDGLSIEGGYP  181
            E  T+D++YY WTQ +F  LY++GLAY A+++VN   +LGT ++NEEV  DG S  GGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRMLRQWILKITAYADKLLEGLDDLDWPESVKQLQRNWIGKSKGALIRF-FMDSGENL  240
            V R+ +RQW+LKITAYA++LLE+L+++DWPES+K++QRNWIGKS GA + F   D++ ++
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  EVFSTRPDTLCGVSFLVLAPEHPLVEKIVLPEKKAEVESYVQEVLGRSERDRISTVKRKS  300
             VF+TRPDTL G ++ VLAPEH+LV+ I  +++   V  Y ++   +S+  R    K K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  301  GVFTGRYAKHPITHEEIPIWIADYVILGYGSGVVMGVPGHDERDREFAETFSLPIHEVIN  360
            GV TG YA +P+   E+P+WIADYV+ +YG+G +M+VP+HDERD+EFA  F+L I  V++
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  361  S----------EGYCIHSSFGEFCLDGLCGQEAREYVIRYLERLGLGEAKVMYKLRDWLF  410
            +          +G  I+S F    LDGL    A   ++  LE  G+G+ +V Y+LRDWLF
Sbjct  364  GGNVEEAAFTEDGLHINSDF----LDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLF  419

Query  411  SRQRYWGEPIPIVHFEDGTSRpleddelpllppdiedYRPEGFGLGPLAKAKDWVDIIDS  470
            SRQRYWGEPIPI+H EDGTS ++ + ELPL+ P   D RP G G +PLA+  DW+++   
Sbjct  420  SRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT-R  478

Query  471  KTGKKGRRETHTMPQWAGSCWYYLRFCDAHNLLAPWSKEKESYWMPVDLYIGGAEHAVLH  530
              G KGRRET+TMPQWAGS WYYLR+ D+HN       E    W+PVD+Y+GGAEHAVLH
Sbjct  479  EDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLH  538

Query  531  LLYARFWHRVFYDGGLVSTKEPFQKLVNQGLVLATSYRLPGKGYVYPEEVHEENGV-WKT  589
            LLYARFWH+V+YD G+V+TKEPFQKL NQG++L+TSYR +  + V  + V+  +G     
Sbjct  539  LLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHV  598

Query  590  ASGEPVLVRQEKMSKSKLNGVDPQTLIEEYGADALRMYAMFSGPLDKNKLWSNQGVAGCR  649
             +GE +     KMSKS  N V+P+ ++E+YGAD+LR+Y MF GPLD +  WS++G+ G R
Sbjct  599  ETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSR  658

Query  650  RFLNRFFELVTSSKVQDVDDQQGLALAYK-LVHRVTEDIEKLSLNTIPSNFMEFLNHFLK  708
            +FL+R + L+T+  + + ++  +L   Y+  V  VTE+++++ +NT  +++M F+N   K
Sbjct  659  KFLDRVYRLITTKEITE-ENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANK  717

Query  709  ----LPVYSKaalalavrvlaPIAPHISEELWVYL-GNDAGIDRALWPQTEERYLQDSLV  763
                ++ Y+K      V+++AP+APH++EELW  L +++ +I    WP  +E  L ++ V
Sbjct  718  EDKLFSDYAK----GFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDV  773

Query  764  TIVVQVNGKLRGCLKLDKDLPKDEV--LLLARKAVDKYLQDVLIKKEIFVPNKLVNFVV  820
             IVVQ++GK+++ L + KDL+++E+  + LA   V+  + +  I K I VPNKLVN+V+
Sbjct  774  EIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

651) leuS in NC_022440


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  650 bits (2456),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 417/839 (50%), Positives = 593/839 (71%), Gaps = 31/839 (3%)

Query  3    YDPSLIEKKWQKFWKENKTFRAIEDTSKEKYYVLDMFPYPSGAGLHVGHLIGYTATDILA  62
            YD + IE KWQ FW +N TF++  D+SK K+Y LDMFPYPSGAGLHVGH  GYTATDIL+
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRARGFSVLHPMGWDSFGLPAEQYAIRTGTHPKLTTKKNIENFKVQLSAMGFSYDEDR  122
            R+KRA+G +VLHPMGWD+FGLPAEQYA+ TG +P   T  NI NFK Q++A+GFSYD DR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EFATSDAEYYHWTQKLFLYLYQQGLAYMADMAVNYCPQLGTVLSNEEV-EDGLSIEGGYP  181
            E  T+D++YY WTQ +F  LY++GLAY A+++VN   +LGT ++NEEV  DG S  GGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRMLRQWILKITAYADKLLEGLDDLDWPESVKQLQRNWIGKSKGALIRF-FMDSGENL  240
            V R+ +RQW+LKITAYA++LLE+L+++DWPES+K++QRNWIGKS GA + F   D++ ++
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  EVFSTRPDTLCGVSFLVLAPEHPLVEKIVLPEKKAEVESYVQEVLGRSERDRISTVKRKS  300
             VF+TRPDTL G ++ VLAPEH+LV+ I  +++   V  Y ++   +S+  R    K K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  301  GVFTGRYAKHPITHEEIPIWIADYVILGYGSGVVMGVPGHDERDREFAETFSLPIHEVIN  360
            GV TG YA +P+   E+P+WIADYV+ +YG+G +M+VP+HDERD+EFA  F+L I  V++
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  361  S----------EGYCIHSSFGEFCLDGLCGQEAREYVIRYLERLGLGEAKVMYKLRDWLF  410
            +          +G  I+S F    LDGL    A   ++  LE  G+G+ +V Y+LRDWLF
Sbjct  364  GGNVEEAAFTEDGLHINSDF----LDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLF  419

Query  411  SRQRYWGEPIPIVHFEDGTSRpleddelpllppdiedYRPEGFGLGPLAKAKDWVDIIDS  470
            SRQRYWGEPIPI+H EDGTS ++ + ELPL+ P   D RP G G +PLA+  DW+++   
Sbjct  420  SRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT-R  478

Query  471  KTGKKGRRETHTMPQWAGSCWYYLRFCDAHNLLSPWSKEKESYWMPVDLYIGGAEHAVLH  530
              G KGRRET+TMPQWAGS WYYLR+ D+HN       E    W+PVD+Y+GGAEHAVLH
Sbjct  479  EDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLH  538

Query  531  LLYARFWHRVFYDGGLVSTKEPFQKLVNQGLVLATSYRLPGKGYVYPEEVHEENGV-WKT  589
            LLYARFWH+V+YD G+V+TKEPFQKL NQG++L+TSYR +  + V  + V+  +G     
Sbjct  539  LLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHV  598

Query  590  ASGEPVLVRQEKMSKSKLNGVDPQTLIEEYGADALRMYAMFSGPLDKNKLWSNQGVAGCR  649
             +GE +     KMSKS  N V+P+ ++E+YGAD+LR+Y MF GPLD +  WS++G+ G R
Sbjct  599  ETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSR  658

Query  650  RFLNRFFELVTSSKVQDVDDHQGLALAYK-LVHRVTEDIEKLSLNTIPSNFMEFLNHFLK  708
            +FL+R + L+T+  + + ++  +L   Y+  V  VTE+++++ +NT  +++M F+N   K
Sbjct  659  KFLDRVYRLITTKEITE-ENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANK  717

Query  709  ----LPVYSKaalalavrvlaPIAPHISEELWVYL-GNDAGIDRALWPQTEERYLQDSLV  763
                ++ Y+K      V+++AP+APH++EELW  L +++ +I    WP  +E  L ++ V
Sbjct  718  EDKLFSDYAK----GFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDV  773

Query  764  TMVVQVNGKLRGCLKLDKDLPKDEV--LLLARKAVDKYLQDVLIKKEIFVPNKLVNFVV  820
             +VVQ++GK+++ L + KDL+++E+  + LA   V+  + +  I K I VPNKLVN+V+
Sbjct  774  EIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

652) leuS in NC_015408


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  650 bits (2456),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 417/839 (50%), Positives = 593/839 (71%), Gaps = 31/839 (3%)

Query  3    YDPSLIEKKWQKFWKENKTFRAIEDTSKEKYYVLDMFPYPSGAGLHVGHLIGYTATDILA  62
            YD + IE KWQ FW +N TF++  D+SK K+Y LDMFPYPSGAGLHVGH  GYTATDIL+
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRARGFSVLHPMGWDSFGLPAEQYAIRTGTHPKLTTKKNIENFKVQLSAMGFSYDEDR  122
            R+KRA+G +VLHPMGWD+FGLPAEQYA+ TG +P   T  NI NFK Q++A+GFSYD DR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EFATSDAEYYHWTQKLFLYLYQQGLAYMADMAVNYCPQLGTVLSNEEV-EDGLSIEGGYP  181
            E  T+D++YY WTQ +F  LY++GLAY A+++VN   +LGT ++NEEV  DG S  GGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRMLRQWILKITAYADKLLEGLDDLDWPESVKQLQRNWIGKSKGALIRF-FMDSGENL  240
            V R+ +RQW+LKITAYA++LLE+L+++DWPES+K++QRNWIGKS GA + F   D++ ++
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  EVFSTRPDTLCGVSFLVLAPEHPLVEKIVLPEKKAEVESYVQEVLGRSERDRISTVKRKS  300
             VF+TRPDTL G ++ VLAPEH+LV+ I  +++   V  Y ++   +S+  R    K K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  301  GVFTGRYAKHPITHEEIPIWIADYVILGYGSGVVMGVPGHDERDREFAETFSLPIHEVIN  360
            GV TG YA +P+   E+P+WIADYV+ +YG+G +M+VP+HDERD+EFA  F+L I  V++
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  361  S----------EGYCIHSSFGEFCLDGLCGQEAREYVIRYLERLGLGEAKVMYKLRDWLF  410
            +          +G  I+S F    LDGL    A   ++  LE  G+G+ +V Y+LRDWLF
Sbjct  364  GGNVEEAAFTEDGLHINSDF----LDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLF  419

Query  411  SRQRYWGEPIPIVHFEDGTSRpleddelpllppdiedYRPEGFGLGPLAKAKDWVDIIDS  470
            SRQRYWGEPIPI+H EDGTS ++ + ELPL+ P   D RP G G +PLA+  DW+++   
Sbjct  420  SRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT-R  478

Query  471  KTGKKGRRETHTMPQWAGSCWYYLRFCDAHNLLSPWSKEKESYWMPVDLYIGGAEHAVLH  530
              G KGRRET+TMPQWAGS WYYLR+ D+HN       E    W+PVD+Y+GGAEHAVLH
Sbjct  479  EDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLH  538

Query  531  LLYARFWHRVFYDGGLVSTKEPFQKLVNQGLVLATSYRLPGKGYVYPEEVHEENGV-WKT  589
            LLYARFWH+V+YD G+V+TKEPFQKL NQG++L+TSYR +  + V  + V+  +G     
Sbjct  539  LLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHV  598

Query  590  ASGEPVLVRQEKMSKSKLNGVDPQTLIEEYGADALRMYAMFSGPLDKNKLWSNQGVAGCR  649
             +GE +     KMSKS  N V+P+ ++E+YGAD+LR+Y MF GPLD +  WS++G+ G R
Sbjct  599  ETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSR  658

Query  650  RFLNRFFELVTSSKVQDVDDQQGLALAYK-LVHRVTEDIEKLSLNTIPSNFMEFLNHFLK  708
            +FL+R + L+T+  + + ++  +L   Y+  V  VTE+++++ +NT  +++M F+N   K
Sbjct  659  KFLDRVYRLITTKEITE-ENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANK  717

Query  709  ----LPVYSKaalalavrvlaPIAPHISEELWVYL-GNDAGIDRALWPQTEERYLQDSLV  763
                ++ Y+K      V+++AP+APH++EELW  L +++ +I    WP  +E  L ++ V
Sbjct  718  EDKLFSDYAK----GFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDV  773

Query  764  TMVVQVNGKLRGCLKLDKDLPKDEV--LLLARKAVDKYLQDVLIKKEIFVPNKLVNFVV  820
             +VVQ++GK+++ L + KDL+++E+  + LA   V+  + +  I K I VPNKLVN+V+
Sbjct  774  EIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

653) CLS_38740 in NC_021047


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  647 bits (2445),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 410/844 (49%), Positives = 574/844 (69%), Gaps = 52/844 (6%)

Query  1    MAQYNHTAIEKKWRENWAKNPI--NVNDGKKEKYYCLDMFPYPSGSGLHVGHWRGYVISD  58
            M+ Y+HTAIE KW+  WA N       D+ K K+Y LDMFPYPSG+GLHVGH  GY  +D
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  59   VWSRYQLLRGKYVIHPMGWDAFGLPAENYAIKMGVHPAKSTAENVKNIKRQINEIAAIYD  118
            + SR++  +G  V+HPMGWDAFGLPAE+YA+  G +PA  TAEN+ N+KRQIN ++  YD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  119  WDMEVNTTDPSFYKWTQWIFVQMFKKGLAYEKEFPINWCPSCKTGLANEEVV-NGCCERC  177
            WD EVNTTDP++YKWTQWIF +++ KGLAYE E P+NW     T++ANEEV+ +G  ER 
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  178  GTPVTKKNLRQWMLKITDYAERLLNDLDKLDWPEKVKKMQSEWIGKSYGAEVDFPVEGRE  237
            G PV +K +RQWMLKIT YAERLL+DL+ +DWPE +K MQ +WIGKS GA+V F V + +
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  238  EKITVYTTRPDTLHGATFMVLAPEHALAKSLATDETREAVEKYIFDSSMKSNVDRLQ-DK  296
              +TV+TTRPDTL GAT+ VLAPEHAL  +++T +  EAV  Y  ++S+KS++ R +  K
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  297  EKTGVFTGSYAINPLNGAKVPIWLSDYVLADYGTGAIMCVPAHDDRDFEFARKFNIPVIQ  356
            EKTGV TGSYAINP+NG  +P+W++DYVLA YGTGAIM VPAHD+RD EFA++FN+ +I 
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  357  VIAKDGKEIENMTEAYTEASGTMINSGEWNGMESSVLKKEAPLMIEKMGIGRKTVNYKLR  416
            V+  +G ++E+   A+TE  G  INS+  +G++ +         +E  G+G   V Y+LR
Sbjct  361  VL--EGGNVEE--AAFTE-DGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  417  DWVFSRQRYWGEPIPIIHCPNCGNVPVPEDQLPLTLPEVDSYQPTGTGESPLAAIDEWVN  476
            DW+FSRQRYWGEPIPIIH  +  + +VPE +LPL LP     +P+GTGESPLA + +W++
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  477  TTCPCCGAPAKRETNTMPQWAGSSWYFLRYVDSKNDKELVSREKADKYLPVDMYIGGVEH  536
             T    G  ++RETNTMPQWAGSSWY+LRY+D+ N   L   E   + LPVD+Y+GG EH
Sbjct  476  VTRE-DGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEH  534

Query  537  AVLHLLYSRFYTKFLYDIGVIDFDEPFKKLFNQGMITG----------------------  574
            AVLHLLY+RF  K LYD+GV+   EPF+KLFNQGMI G                      
Sbjct  535  AVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGS  594

Query  575  -----------KNGIKMSKSKGNVVSPDDLVRDYGCDSLRLYELFVGPPELDAEWDDRGI  623
                       +   KMSKS  NVV+PDD+V +YG D+LR+YE+F+GP +    W + G+
Sbjct  595  FFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGL  654

Query  624  EGVSRFLNRFYNLVMSSKDKDIKETKEMVKLRHKLVYDIEQRFEQFSLNTVISGFMEYNN  683
            EG  +FL+R Y L+ ++K+    ++  + K+ +  V  + ++ +Q  +NT I+ +M +  
Sbjct  655  EGSRKFLDRVYRLI-TTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVF--  711

Query  684  KLIELSKKEGGIDRETLKTFVVLLAPFAPHLGEELWRELGGT-DSVFHSTWPECDEEAMK  742
              ++ ++KE+ +  +  K FV L+APFAPHLGEELW+ L ++ +S+    WP  DE  + 
Sbjct  712  --VNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLV  769

Query  743  DDEIQIAVQINGKTRG--LVTLPadadkeaalaagkeavkdKLTGT-IVKEIYVPGKIIN  799
            +++++I VQI+GK ++  +V+     +    +A ++E V+  ++G  I+K I VP K++N
Sbjct  770  ENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVN  829

Query  800  IVVK  803
            IV+K
Sbjct  830  IVIK  833

654) leuS in NC_002620


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  645 bits (2438),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 405/817 (50%), Positives = 585/817 (72%), Gaps = 24/817 (2%)

Query  21   TFRAEEDETKTKYYVLDMFPYPSGAGLHVGHLIGYTATDIVARYKRAKGFSVLHPMGWDS  80
            TF++  D +K K+Y LDMFPYPSGAGLHVGH  GYTATDI++R+KRA+G +VLHPMGWD+
Sbjct  22   TFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSRFKRAQGHNVLHPMGWDA  81

Query  81   FGLPAEQYAIRTGTHPRETTEKNIANFKQQLTSMGFSYDESREFATSDPEYYKWTQKLFL  140
            FGLPAEQYA+ TG +P E T  NIANFK+Q+ ++GFSYD  RE  T+DP+YYKWTQ +F 
Sbjct  82   FGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFT  141

Query  141  ILYEKGLAYMADMAVNYCPELGTVLSNEEV-ENGFSVEGGYPVERRMLRQWVLRITAFAD  199
             LYEKGLAY A+++VN   ELGT ++NEEV  +G S  GGYPV R+ +RQW+L+ITA+A+
Sbjct  142  KLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAE  201

Query  200  QLLGGLDELDWPESVKQLQRNWIGKSVGASVHFETEHGVLE--VFTTRPDTLIGVSFLVL  257
            +LL +L+E+DWPES+K++QRNWIGKS GA+V F   +   +  VFTTRPDTL+G ++ VL
Sbjct  202  RLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVL  261

Query  258  APEHPLVDLLTSDEQKTIVAQYVKETQSKSERDRISEMKTKSGVFTGAYAKHPVTQNPIP  317
            APEH+LVD +T+ +Q   VA+Y +++  KS+  R    K K+GV TG+YA +PV  + +P
Sbjct  262  APEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAINPVNGKEMP  321

Query  318  IWIADYVLMGYGSGAVMGVPAHDDRDLLFAQQFDLPIISVVSEDGVCINS-------CHE  370
            +WIADYVL +YG+GA+M+VPAHD+RD  FA+QF+L II+V+  + V   +        + 
Sbjct  322  VWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEAAFTEDGLHINS  381

Query  371  DFSLDGLSGEEAKQYVINFLEKNNLGSAKVAYKLRDWLFSRQRYWGEPIPVIHFEDGSCR  430
            DF LDGL    A   +++ LE + +G+ +V+Y+LRDWLFSRQRYWGEPIP+IH EDG+  
Sbjct  382  DF-LDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTST  440

Query  431  plkddelpllppeIQDYRPEGVGQGPLAKVKEWVNVFDSETQKEGKRETHTMPQWAGSCW  490
            ++ + ELPL+ P  +D RP G G++PLA+V +W++V   +  K G+RET+TMPQWAGS W
Sbjct  441  AVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK-GRRETNTMPQWAGSSW  499

Query  491  YYLRFCDAHNSCAPWAEEKEQYWMPVDLYIGGAEHAVLHLLYARFWHQVFYEAGIVSTPE  550
            YYLR+ D+HN+     EE  + W+PVD+Y+GGAEHAVLHLLYARFWH+V+Y+ G+V+T E
Sbjct  500  YYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKE  559

Query  551  PFKKLVNQGLVLSTSYRIPGKGYIAPEMAKEENGQWIS-PSGELLDVRQEKMSKSKLNGV  609
            PF+KL NQG++L+TSYR +  + +A +     +G  +   +GE L+    KMSKS  N V
Sbjct  560  PFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVV  619

Query  610  DPKVLIDEFGADAVRMYAMFSGPLDKNKLWSNQGVAGCRRFLNRFYEMATSSRVKDEDIF  669
            +P  +++++GAD++R+Y MF GPLD +  WS++G+ G R+FL+R Y + T+  + +E+  
Sbjct  620  NPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITEENSG  679

Query  670  EGMSLAHKLVQRVTDDIEKLSLNTITSSFMEFINEFVK----LPVYPKNAVEMAVRALAP  725
                + +  V+ VT++++++ +NT  + +M F+N   K    ++ Y+K  V++    +AP
Sbjct  680  ALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQL----IAP  735

Query  726  IAPHISEELW-VLLGNASGIEKAGWPKALPEYLEGKIVTIVVQVNGKLRARLDISKDaie  784
            +APH++EELW  L +++ +I    WP      L  + V IVVQ++GK++A+L ++KD   
Sbjct  736  FAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSR  795

Query  785  e--evvalakeavSKYLEGGVVRKTIFVLNRLVNFVI  819
            E  + VALA+E V   + G  + K I V N+LVN+VI
Sbjct  796  EELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

655) leuS in NC_010376


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  645 bits (2436),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 412/840 (50%), Positives = 583/840 (70%), Gaps = 51/840 (6%)

Query  4    YNPNSIEKKWQKYWEENktfktsddkskkrfYALVEFPYPSGQGLHVGHPRPYTALDIVS  63
            Y+  +IE KWQ +W +N TFKT+ D SK +FYAL  FPYPSG GLHVGHP  YTA DI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RKRRMQGYNVLYPMGWDAFGLPTENFAIKNKIRPEVVTENNIKNFKRQMQSIGFSFDWDR  123
            R +R QG NVL PMGWDAFGLP+E++A+     P   T +NI NFKRQ++++GFS+DWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EINTTDPDYYKWTQWIFIQMFKKGLAYKKEMPINWCPSCKTGLANEEVI-NGHCERCGGQ  182
            E+NTTDP+YYKWTQWIF +++ KGLAY  E+P+NW     T++ANEEV+ +G  ER G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VVRKVKNQWMLKITEYADRLIDDLKDVDYFDRIKSQQINWIGRSYGAEINFAVKEVDEKI  242
            VVRK   QWMLKIT YA+RL++DL +VD  + IK  Q NWIG+S GA++ F VK+ D  +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  243  TVFTTRADTIFGATYMVISVDHPLIEKYSDRIKNIDEIRSYRSEVAKKSELERTDLSKEK  302
            TVFTTR+DT+FGATY V++ +H+L++  +    + + +  Y+ + + KS+L RTDL+KEK
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTS-DQAEAVADYKRQASLKSDLARTDLAKEK  302

Query  303  TGYKIDGLTAINPLTNKEIPVYVSDYVLMTYGTGAIMAVPAHDDRDYEFAKKFNIEMIPV  362
            TG   ++  AINP+  KE+PV ++DYVL +YGTGAIMAVPAHD+RD EFAK+FN+++IPV
Sbjct  303  TGVWTGSY-AINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  363  IEGSDIQNCAFTETNEGNLINSGFLNGLTVDeakekmyeyieekeiGHKKTNYKLRDWVF  422
            +EG+++++ AFTE  +G  INS+FL+GL    A  KM E +E   +G+ +  Y+LRDW+F
Sbjct  362  LEGGNVEEAAFTE--DGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLF  419

Query  423  SRQRYWGEPIPLVYCEHCGWVPLDEKDLPLVLPKVDNYEPTDNGESPLSKIDDFVHTKCP  482
            SRQRYWGEPIP++  E+    ++ E +LPLVLP   +  P++ GESPL+++ D ++    
Sbjct  420  SRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRE  479

Query  483  KCGRDAVRETDTMPQWAGSSWYYLRYTDPHNDEAIASKENLDYYTPVDWYNGGMEHTTLH  542
               ++  RET+TMPQWAGSSWYYLRY DPHN E +A  E L    PVD Y GG EH+ LH
Sbjct  480  DGVKGR-RETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLH  538

Query  543  LLYSRFWHKFLYDIGVVPTKEPYMKRTSHGMILG--------------------------  576
            LLY+RFWHK LYD+GVVPTKEP+ K  ++GMILG                          
Sbjct  539  LLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHV  598

Query  577  -------DNNEKMSKSRGNVVNPDDIVRDFGADTLRCYEMFIGDFEKSAPWSENGVKGCR  629
                   +   KMSKS  NVVNPDD+V ++GADTLR YEMF+G ++ S +WSE+G+ G R
Sbjct  599  ETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSR  658

Query  630  KFLDKVWR---TQDLVDGDSNFEKMETLIHQTIKKVSEDYENLKFNTAIAQLMTLLNEFN  686
            KFLD+V R   T+++ + +S    ++ + ++T+K V+E+ +++KFNTAIAQLM ++N  N
Sbjct  659  KFLDRVYRLITTKEITEENSG--ALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN  716

Query  687  NLDKISKEQFKIFLILLNPVCPHITEEIWQRMGYEG----YVHESSWPEYDESKTILDVI  742
            + DK+  +  K F+ L+ P  PH+ EE+WQ +   G    YV   +WP YDESK + + +
Sbjct  717  KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYV---PWPSYDESKLVENDV  773

Query  743  ELPIQVNGKLRATVEINREASEDEVYEKAVKDDVVAKYLENKNVVKKIYVKGRIFNIIVK  802
            E+ +Q++GK++A + + ++ S +E+ E A+ ++ V   +  K+++K I V  ++ NI++K
Sbjct  774  EIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

656) CK1_11530 in NC_021014


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  641 bits (2424),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 399/842 (48%), Positives = 563/842 (67%), Gaps = 53/842 (6%)

Query  5    YNHRAIEAKWRTNWEKKPV--NVNDGKKPKYYCLDMFPYPSGNGLHVGHWRGYVISDVWS  62
            Y+H AIE+KW++ W  +       D+ KPK+Y LDMFPYPSG GLHVGH  GY  +D+ S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKMLQGYYLIHPMGWDAFGLPAENYAIKMGVHPAVSTAANIKNIKRQINDIAAIYDWDM  122
            R+K  QG  ++HPMGWDAFGLPAE+YA+  G +PA  TA NI N+KRQIN ++  YDWD 
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVNTTDPEFYKWTQWIFVKMFKEGLAYEKEFPINWCPSCKTGLANEEVV-NGCCERCGTP  181
            EVNTTDP++YKWTQWIF K++  GLAYE E P+NW     T++ANEEV+ +G  ER G P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VTKKNLRQWMLRITKYADRLLSDLDKLDWPEKVKKMQTDWIGKSYGAEVDFPVEGREEKI  241
            V +K +RQWML+IT YA+RLL DL+ +DWPE +K MQ +WIGKS GA+V F V + +  +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  TVYTTRPDTLHGATFMVLAPEHALAKSLATDETREAVEKYIFDASMKSNVDRLQ-DKEKT  300
            TV+TTRPDTL GAT+ VLAPEHAL  +++T +  EAV  Y  +AS+KS++ R +  KEKT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  301  GVFTGTYAINPLNGEKLPIWLSDYVLADYGTGAIMCVPAHDDRDFEFAKKFDIPIIQVIA  360
            GV TG+YAINP+NG  +P+W++DYVLA YGTGAIM VPAHD+RD EFAK+F++ II V+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL-  362

Query  361  KDGKEIQNMTEAYTEASGTMINSGEWNGMESSVLKKEAPHIIEKLGIGRKTVNYKLRDWV  420
             +G ++++   A+TE  G  INS+  +G++ +       + +E  G+G   V Y+LRDW+
Sbjct  363  -EGGNVEE--AAFTE-DGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWL  418

Query  421  FSRQRYWGEPIPIVHCPKCGAVPVPEDQLPLRLPEVESYQPTGTGESPLAAIDEWVNTTC  480
            FSRQRYWGEPIPI+H     + +VPE +LPL LP     +P+GTGESPLA + +W++ T 
Sbjct  419  FSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTR  478

Query  481  PCCGAPAKRETNTMPQWAGSSWYFLRYVDNKNNKELVSKEKADKYLPVDMYIGGVEHAVL  540
               G  ++RETNTMPQWAGSSWY+LRY+D  N   L   E   + LPVD+Y+GG EHAVL
Sbjct  479  E-DGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVL  537

Query  541  HLLYSRFYTKFLYDIGAIDFDEPFVKLFNQGMITG-------------------------  575
            HLLY+RF  K LYD+G +   EPF KLFNQGMI G                         
Sbjct  538  HLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFH  597

Query  576  --------KNGIKMSKSKGNVISPDDLVNDYGCDSLRMYELFVGPPELDAEWDDRGIDGV  627
                    +   KMSKS  NV++PDD+V++YG D+LR+YE+F+GP +    W + G++G 
Sbjct  598  VETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGS  657

Query  628  SRFLKRFWNLALDSIEKDIPATKEMEKTRHKMVYDITSRLEAFSLNTVVSGFMEYTNKLI  687
             +FL R   L + + E     +  ++K  +  V  +T +++   +NT ++ +M + N   
Sbjct  658  RKFLDRVYRL-ITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVN---  713

Query  688  AIAKQNDGAVDKETIKTVTILLAPFVPHIAEEIWEKL-GHEDSIFHAQWPAHDEELMKDD  746
              A ++++ +  +  K    L+APF PH++EE+W+ L +  +SI    WP+ DE  + ++
Sbjct  714  --AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVEN  771

Query  747  EIEVPVQINGKTKAVISIPAEISKED--AIAEGKKAVADKISG-NIIKEIYVPKKIINIV  803
            ++E+ VQI+GK KA + ++ ++S+E+   +A ++  V   I+G +IIK I VP+K++NIV
Sbjct  772  DVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIV  831

Query  804  VK  805
            +K
Sbjct  832  IK  833

657) CK3_29100 in NC_021035


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  638 bits (2412),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 415/844 (50%), Positives = 576/844 (69%), Gaps = 52/844 (6%)

Query  1    MAQYNHTAIESKWRENWEKNPI--NVNDGKKEKYYCLDMFPYPSGSGLHVGHWRGYVISD  58
            M+ Y+HTAIE+KW+  W  N       D+ K K+Y LDMFPYPSG+GLHVGH  GY  +D
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  59   VWSRYQLLKGKYVIHPMGWDAFGLPAENYAIKMGVHPAISTASniknikrqinqiAALYD  118
            + SR++  +G  V+HPMGWDAFGLPAE+YA+  G +PA  TA NI N+KRQIN ++  YD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  119  WDMEVNTTDPSFYKWTQWIFVQMFKKGLAYEKEFPINWCPSCKTGLANEEVV-NGCCERC  177
            WD EVNTTDP++YKWTQWIF +++ KGLAYE E P+NW     T++ANEEV+ +G  ER 
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  178  GTPVTKKNLRQWMLKITAYADRLLNDLDKLDWPEKVKKMQTDWIGKSYGAEVNFPVKGRD  237
            G PV +K +RQWMLKITAYA+RLL+DL+ +DWPE +K MQ +WIGKS GA+V F VK+ D
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  238  EKITVYTTRPDTLHGATFMVLSPEHKLAKELATDETREAVEKYIFDASMKSNVDRLQ-GK  296
              +TV+TTRPDTL GAT+ VL+PEH L   ++T +  EAV  Y  +AS+KS++ R + +K
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  297  EKTGVFTGSYAINPLNGKEVPIWLSDYVLADYGTGAIMCVPAHDDRDFEFAKKFGLPIIQ  356
            EKTGV TGSYAINP+NGKE+P+W++DYVLA YGTGAIM VPAHD+RD EFAK+F L II 
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  357  VIAQDGKEIENMTEAYTDAKGTMINSGEWNGMESSVLKKEAPHIIEKMGIGKKTVNYKLR  416
            V+  +G ++E+   A+T+  G  INS+  +G++ +       + +E  G+G+  V Y+LR
Sbjct  361  VL--EGGNVEE--AAFTED-GLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  417  DWVFSRQRYWGEPIPIVHCPKCGNVPVPEDQLPLKLPEVESYQPTGTGESPLAAIDSWVN  476
            DW+FSRQRYWGEPIPI+H     + +VPE +LPL LP     +P+GTGESPLA +  W++
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  477  TTCPCCGAPAKRETNTMPQWAGSSWYFLRYVDNKNDQELVSKEKADKYLPVDMYIGGVEH  536
             T    G  ++RETNTMPQWAGSSWY+LRY+D  N + L   E   + LPVD+Y+GG EH
Sbjct  476  VTRE-DGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEH  534

Query  537  AVLHLLYSRFYTKFLYDIGVIDFDEPFKKLFNQGMITG----------------------  574
            AVLHLLY+RF  K LYD+GV+   EPF+KLFNQGMI G                      
Sbjct  535  AVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGS  594

Query  575  -----------KNGIKMSKSKGNVVSPDDLVRDYGCDALRMYELFVGPPELDAEWDDRGI  623
                       +   KMSKS  NVV+PDD+V +YG D+LR+YE+F+GP +    W + G+
Sbjct  595  FFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGL  654

Query  624  EGVARFLNRFYNLVMDSKDKDIKETKEMVKLRHKLVYDIETRFNQFSLNTVVSGFMEYCN  683
            EG  +FL+R Y L+  +K+    ++  + K+ +  V  +  + +Q  +NT ++ +M + N
Sbjct  655  EGSRKFLDRVYRLI-TTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVN  713

Query  684  KLTDVAKKEGGIDKETLKTFVILLAPFTPHLGEELWRELGGT-DSVFHATWPECDEEAMK  742
                 A+KE+ +  +  K FV L+APF+PHLGEELW+ L ++ +S+    WP  DE  + 
Sbjct  714  ----AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLV  769

Query  743  DDEIEVAVQVNGKVKAVIMVPa--diakedaiaagkaavegKITG-NIVKEIYVPKKIVN  799
            ++++E+ VQ++GKVKA ++V+        + +A ++  V++ I+G +I+K I VP+K+VN
Sbjct  770  ENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVN  829

Query  800  IVVK  803
            IV+K
Sbjct  830  IVIK  833

658) Closa_1685 in NC_014376


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  638 bits (2413),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 410/841 (49%), Positives = 577/841 (69%), Gaps = 52/841 (6%)

Query  5    YNHSAIEKKWRENWAKSPI--NVDDGKKKKYYCLDMFPYPSGSGLHVGHWRGYVISDVWS  62
            Y+H+AIE KW+  WA +       D+ K K+Y LDMFPYPSG+GLHVGH  GY  +D+ S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYQILKGHYVIHPMGWDAFGLPAENYAIKMGVHPAKSTAENVSNIKRQINEIAAVYDWDM  122
            R++  +GH V+HPMGWDAFGLPAE+YA+  G +PA  TAEN++N+KRQIN ++  YDWD 
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVNTTDPEFYKWTQWIFVQMFKKGLAYEKEFPINWCPSCKTGLANEEVV-NGCCERCGTG  181
            EVNTTDP++YKWTQWIF +++ KGLAYE E P+NW     T++ANEEV+ +G  ER G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VTKKNLRQWMLKITAYAdrllddldkldWPEKVKKMQTEWIGKSYGAEVDFKVDGREEAV  241
            V +K +RQWMLKITAYA+RLL+DL+ +DWPE +K MQ +WIGKS GA+V FKV + +   
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  TVYTTRPDTLYGATFMVLAPEHALASGLATPENKEAVEKYIYDASMKSNVDRLQ-DKEKT  300
            TV+TTRPDTL+GAT+ VLAPEHAL  +++T+++ EAV  Y  +AS+KS++ R +  KEKT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  301  GVFTGSYAVNPLSGAKVPIWLSDYVLADYGTGAIMCVPAHDDRDFEFAKKFNIPIIQVIA  360
            GV TGSYA+NP++G  +P+W++DYVLA YGTGAIM VPAHD+RD EFAK+FN+ II V+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL-  362

Query  361  KDGREIENMTEAYTEASGTMINSGEWNGMESSVLKKDAPAMIEERGLGKKTVNFKLRDWV  420
             +G ++E+   A+TE  G  INS+  +G++ +         +E  G+G+  V ++LRDW+
Sbjct  363  -EGGNVEE--AAFTE-DGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWL  418

Query  421  FSRQRYWGEPIPIIHCPHCGNVPVPEDQLPLTLPEVESYQPTGTGESPLADIDEWVNTTC  480
            FSRQRYWGEPIPIIH  +  + +VPE +LPL LP     +P+GTGESPLA++ +W++ T 
Sbjct  419  FSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTR  478

Query  481  PVCGAPAKRETNTMPQWAGSSWYFLRYVDSHNDQELVSKEKAKKYLPVDMYIGGVEHAVL  540
               G  ++RETNTMPQWAGSSWY+LRY+D+HN + L   E  K+ LPVD+Y+GG EHAVL
Sbjct  479  E-DGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVL  537

Query  541  HLLYSRFYTKFLNDIGVVDFDEPFTKLFNQGMING-------------------------  575
            HLLY+RF  K L D+GVV   EPF KLFNQGMI G                         
Sbjct  538  HLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFH  597

Query  576  --------KNGIKMSKSKGNVVSPDDLVRDYGCDALRMYELFVGPPELDAEWDDRGIEGV  627
                    +   KMSKS  NVV+PDD+V +YG D+LR+YE+F+GP +    W + G+EG 
Sbjct  598  VETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGS  657

Query  628  GRFLNRFWKLVTESSNKDVEPTREMLRLRSKLIFDIEQRFSQFNLNTVISGFMEYNNKFI  687
             +FL+R  +L+T     + E +  + ++ +  +  + ++  Q ++NT I+ +M     F+
Sbjct  658  RKFLDRVYRLITTKEITE-ENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMV----FV  712

Query  688  EMAQKTGGIDKETLKAFVVLVAPFAPHIGEELWQRLGGMT-SVFHAQWPVCDEEAMKEDE  746
            + A+K + +  +  K+FV L+APFAPH+GEELWQ L +   S+    WP  DE  + E++
Sbjct  713  NAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVEND  772

Query  747  IEVAVQVNGKTRAVVKLPVNVSKEE--AIEAGKALIPDKITGT-IVKEIYVPGRIVNIVC  803
            +E+ VQ++GK +A + ++ ++S+EE   +  ++  +   I+G  I+K I VP ++VNIV 
Sbjct  773  VEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

Query  804  K  804
            K
Sbjct  833  K  833

659) leuS in NC_017803


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  638 bits (2411),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 435/920 (48%), Positives = 595/920 (65%), Gaps = 101/920 (10%)

Query  16   GEIELRWQRYWAENGTFHAPNPTGELADPGHPRAGAPKLHVQDMFPYPSGAGLHVGHPLG  75
              IE +WQ +WA+N TF +   ++            PK+   DMFPYPSGAGLHVGHP G
Sbjct  7    TAIEPKWQAFWADNHTFKTGTDASK-----------PKFYALDMFPYPSGAGLHVGHPEG  55

Query  76   YIGTDCYTRFQRMAGYNVLHPMGFDAFGLPAEQYAVQTGTHPAVTTAANVERYRQQLRRL  135
            Y +TD  +RF+R  G NVLHPMG DAFGLPAEQYA++TG +PA  TA N+  +++Q+  L
Sbjct  56   YTATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINAL  115

Query  136  GLAYDERRSFSTTDPEYYRWTQWIFLQVFNSWFDPEQGRARPIDELIASYEAGERGAAWA  195
            G++YD  R  +TTDP+YY+WTQWIF ++                     YE G       
Sbjct  116  GFSYDWDREVNTTDPNYYKWTQWIFTKL---------------------YEKG-------  147

Query  196  TLSPAERRKVIDGHRLAYVSEAPVNWCPGLGTVLANEEVTPDGRSERGNYPVFQRSLKQW  255
                           LAY +E PVNW   LGT +ANEEV PDG SERG YPV +++++QW
Sbjct  148  ---------------LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQW  192

Query  256  MMRITAYGDRLVDDLDALDWPEPVKLMQRNWIGRSQGAHVDFAV-DADR-ITVFTTRPDT  313
            M++ITAY++RL++DL+ +DWPE++K MQRNWIG+S GA+V F V D+D+ +TVFTTRPDT
Sbjct  193  MLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDT  252

Query  314  LFGATYMVLAPEHALVSKIVPAAWPAGTKEAWKVAGTPAEAVEAYRVtaaakteeertaD  373
            LFGATY VLAPEHALV  I               ++  AEAV  Y+  A+ K++  RT  
Sbjct  253  LFGATYAVLAPEHALVDAIT--------------TSDQAEAVADYKRQASLKSDLARTDL  298

Query  374  GKVKTGVFTGAYAVNPVNGASIPVFIADYVLAGYGTGAIMAVPGHDQRDFEFATVFELPV  433
            +K KTGV TG+YA+NPVNG  +PV IADYVLA+YGTGAIMAVP+HD+RD EFA  F+L +
Sbjct  299  AKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDI  358

Query  434  VRTIATPEGCEGAYVGDGEVINSEFLNGLNKDEAKAAMIAWLEERGKGAGATTYRLRDWL  493
            +  +   +  E+A+  DG  INS+FL+GL+K  A A M+ WLE  G G    TYRLRDWL
Sbjct  359  IPVLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWL  418

Query  494  FSRQRYWGEPFPIVYDETGLPIALPESMLPVELPDVDDFSPRTFdpddadtepetpLSRK  553
            FSRQRYWGEP+PI+  E G + A+PES LP+ LP   D+ P            E+PL+  
Sbjct  419  FSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSG--------TGESPLANV  470

Query  554  KEWVQVELDLGDGPRMYTRETNTMPQWAGSCWYELRYLDPHNDHALVDPANEAYWMGPQR  613
             +W++V  + G   R   RETNTMPQWAGS WY LRY+DPHN + L D      W+    
Sbjct  471  TDWLEVTREDGVKGR---RETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWL----  523

Query  614  PGDPGGVDLYVGGVEHAVLHLLYARFWHKVLFDLGHVSSFEPFRKLFNQGYIQAYAFRDA  673
                  VD+YVGG EHAVLHLLYARFWHKVL+DLG V++ EPF+KLFNQG I + ++RD+
Sbjct  524  -----PVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDS  578

Query  674  RGVIVPAEEVVERDGKWYHGD--QEVAREYGKMGKSLKNVVTPDEMCDQYGADTFRVYEM  731
            RG +V+++ V  RDG  +H +  +E+ +  +KM+KSLKNVV PD++ +QYGADT+RVYEM
Sbjct  579  RGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEM  638

Query  732  AMGPLDVSRPWETRAVVGSQRFLQRVWRLVVDEETGAIRVTDAELDPKSRKVLHRVIAGV  791
             MGPLD S +W   ++ GS++FL+RV RL+   E        + LD    KV +  + +V
Sbjct  639  FMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITE--ENSGALD----KVYNETVKAV  692

Query  792  REDMAELRFNTAIAKLIELTNTLTPLATVSREAVEPLVLMLSPFAPHLAEELWGRLGHAG  851
             E++ +++FNTAIA+L+ + N+      +  +    +V +++PFAPHL+EELW  L  +G
Sbjct  693  TEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASG  752

Query  852  -TLAYADFPQADPAQLVADSITYPVQVNGKVRGRVEVAPDTPea--evraqalaavaeal  908
             +++Y   P  D ++LV + +   VQ++GKV++++ VA D +    +  A A   V   +
Sbjct  753  ESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEI  812

Query  909  GGKEPKKVIVVKGRLVSVVV  928
            +GK+  KVI V  +LV++V+
Sbjct  813  AGKDIIKVIAVPNKLVNIVI  832

660) leuS in NC_013511


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  637 bits (2409),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 409/847 (49%), Positives = 592/847 (70%), Gaps = 60/847 (7%)

Query  2    YKHNEIEQKWRKFWAENKSFATGNNSNK-KAYILDMFPYPSGMGLHVGHLEGYTATDIIA  60
            Y H  IE KW+ FWA+N +F TG +++K K Y LDMFPYPSG GLHVGH EGYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  61   RYKRLNGFDVLHPIGWDAFGLPAEQYAIKTGNDPEPFTLKNIANFRRQLQAMGFSYDYDK  120
            R+KR +G +VLHP+GWDAFGLPAEQYA+ TGNDP  FT  NIANF+RQ++A+GFSYD D+
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  121  EVNTTDPKFYIWTQWIFKEMYKQGLASIEEIDVNWCEGLGTVLANEEILEKNGIKVSERG  180
            EVNTTDP++Y WTQWIF  +Y +GLA   E+ VNW E LGT +ANEE+L       SERG
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDG---TSERG  180

Query  181  NFPVVKKPMKQWVLKITAYADKLLEGLEDLDWPESLKQLQRNWIGRSKGHIVKWNISSSE  240
             +PVV+KPM+QW+LKITAYA++LLE+LE++DWPES+K++QRNWIG+S G  V  ++  ++
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  241  QQKLQLSTFTTRLDTIYGVTAIVISPEHPLLQKITTAKYHDDISNYLKEVKLKNELERTS  300
            +   +++ FTTR DT++G T  V++PEH+L++ ITT+   + +++Y ++  LK++L RT 
Sbjct  241  K---DFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTD  297

Query  301  LNKDKTGYFTGSYAIHPLTNELIPIWVSDYVLMSYGSGAVMCVPGHDQRDYEFAKKFDLR  360
            L K+KTG  TGSYAI+P+    +P+W++DYVL SYG+GA+M VP+HD+RD EFAK+F+L 
Sbjct  298  LAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLD  357

Query  361  IKKIIE---CDELPFLGDGIHINSDIANGLDNAGAVKCIFNELKANNLADEKVSYKLRDW  417
            I  ++E    +E +F  DG+HINSD+ +GLD+A+A+  + + L A+ +++E+V+Y+LRDW
Sbjct  358  IIPVLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDW  417

Query  418  IFSRQRYWGEPFPVLFDEENNIYLVKE---LVELPKIKNIKPSGTTSGPLANVESWMNVE  474
            +FSRQRYWGEP+P++  E+     V E    + LP  K+I+PSGT  +PLANV  W++V 
Sbjct  418  LFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT  477

Query  475  -INGKKYHHDTNVMPQWAGSSWYYLAYILKNPDGSYTPLNSSEAKKRFEEWMPVDLYIGG  533
              +G K +++TN MPQWAGSSWYYL YI  +P+ +   L   E  K   +W+PVD+Y+GG
Sbjct  478  REDGVKGRRETNTMPQWAGSSWYYLRYI--DPHNT-EKLADEELLK---QWLPVDIYVGG  531

Query  534  QEHAVLHLLYARFWHRFLFDLGIVNTKEPFTKLINQGLIMGP------------------  575
             EHAVLHLLYARFWH+ L+DLG+V TKEPF KL+NQG+I+G                   
Sbjct  532  AEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKR  591

Query  576  ---------------DGQKMSKSLGNVINPDDFILSHGADSLRVYEMFMGPLVESKSWST  620
                              KMSKSL NV+NPDD +   GAD+LRVYEMFMGPL  S +WS 
Sbjct  592  DGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSE  651

Query  621  DSLNGIRRWIEKIYNIFEYFVKGnidinnsnnelisninklileVSENIEKTKFNIAISK  680
            ++L+G R+ ++++Y +    +  +   ++++  L    N  +  V+E++++ KFN AI++
Sbjct  652  EGLEGSRKFLDRVYRL----ITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQ  707

Query  681  MMVFTNYLTSLKTIPSSFVLKQFAILLSPFAPFLAEEL--LFMLNEKPIQYQTWPYADET  738
            +MVF N       + S +  K F  L++PFAP L+EEL   +  +  +I Y  WP  DE+
Sbjct  708  LMVFVNAANKEDKLFSDYA-KGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDES  766

Query  739  kiiikniqigiqingKVRSQIEILPNWSNEEIIENAKKLDNVAKWLQGHEIVKVIYKDFK  798
            K++ ++++I +QI+GKV++++ +  + S EE+ E A   ++V   + G +I+KVI    K
Sbjct  767  KLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNK  826

Query  799  ILNFIIK  805
            ++N++IK
Sbjct  827  LVNIVIK  833

661) leuS in NC_016894


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  633 bits (2392),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 399/838 (48%), Positives = 565/838 (68%), Gaps = 40/838 (4%)

Query  1    MSTYEHKKIEEKWQKHWEENETFRMEENSDKEKFYGLVEFPYPSGVGLHVGHVRAYTSLE  60
            M+ Y+H  IE KWQ  W +N+TF+   ++ K KFY+L  FPYPSG GLHVGH  +YT+ +
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   VIARKRRMEGFNVLFPIGWDAFGLPTENYAIQTGRHPRAVTDENIAVFTNQLKRIGYAFD  120
            +++R +R +G NVL P+GWDAFGLP+E+YA++TG +P   T ENIA F  Q++ +G+++D
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WDKEIDTTDPKYYKWTQWIFLQLFKHGLAFRDRTYVNFCNGCKVVLANED-FRDGKCDRC  179
            WD+E++TTDP+YYKWTQWIF +L+  GLA+     VN  +     +ANE+ + DG  +R 
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  180  GSEVVQMEKDVWFLKIRNYAEELLKGLDDVNYLPRIRLEQENWIGKSVGAEVDFTIAGYD  239
            G  VV+     W LKI  YAE LL +L++V+    I+  Q NWIGKS GA+V F + + D
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  240  KKLRVFTTRPDTLFGATFMVIAPEHPLIEDLSESITNMAELIDYQDQAKRKTEFERVQLA  299
            K + VFTTRPDTLFGAT+ V+APEH+L++ ++ S  +   + DY+ QA  K+++ R +LA
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTS-DQAEAVADYKRQASLKSDLARTDLA  299

Query  300  KEKTGVRILGIQAINPVTNSEIPIFIADYVMMGYGTGAIMAVPGHDNRDWDFAKKFDLPI  359
            KEKTGV+  G  AINPV   E+P+ IADYV+ +YGTGAIMAVP+HD+RDW+FAK+F+L I
Sbjct  300  KEKTGVWT-GSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDI  358

Query  360  IEVIKGGDVSEAAYTNTDSGKMVNSGFLNGLEVKDAIQKTIDFLENEKLGKRTINYKMKD  419
            I V+ GG+V EAA+  T+ G  +NS+FL+GL+   AI K ++ LE E +G+  + Y+++D
Sbjct  359  IPVLEGGNVEEAAF--TEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WAFNRQRYWGEPIPIIHCPKCGMvpvpeaelplelpvveTYTPTDTGKSPLANIPEWYQT  479
            W F+RQRYWGEPIPIIH       +VPE+ELPL LPV     P++TG SPLAN+ +W + 
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  480  TCPVCGGAAERETDTMPQWAGSSWYFLRYFDNKNDEAFASEEKLKYWMPVDWYNGGMEHV  539
            T    G  + RET+TMPQWAGSSWY+LRY+D  N E +A EE LK W+PVD Y GG EH 
Sbjct  477  TRE-DGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  540  TRHLLYSRFWHQFLFDIGCVPVREPYAKRTAQGLILG-----------------------  576
              HLLY+RFWH+ L+D+G VP +EP+ K   QG+ILG                       
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSF  595

Query  577  ----------NDGEKMSKSKGNVVNPNDIIEEFGADTLRTYIMFIGDYEKSAPWSDNGAK  626
                      +   KMSKS  NVVNP+D++E++GADTLR Y MF+G  + S +WS++G  
Sbjct  596  FHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLE  655

Query  627  GCRRFLDRVWKLQDMVSAEAGYGKALESTIHKTIKKVNDDYEEMKYNTAIAALMTLVNEF  686
            G R+FLDRV +L          + AL+   + T+K V ++ ++MK+NTAIA LM +VN  
Sbjct  656  GSRKFLDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAA  715

Query  687  NRENELTRDAFKTFLQLLYPVAPHVTSEIWENMEMGGN-LDDAPWPQYDEAKTVDDVIEM  745
            N+E+ L  D  K F+QL+ P APH+  E+W+ +  +G+ +   PWP YDE+K V++ +E+
Sbjct  716  NKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEI  775

Query  746  AVQINGKVRGTITIPVdadkeaakaialaHENILAYTQGKTVVKEIYVPGKIFNIVVK  803
             VQI+GKV++ + ++ D  +E  + +ALA+E++ A   GK ++K I VP K+ NIV+K
Sbjct  776  VVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

662) Clocl_1028 in NC_016627


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  633 bits (2394),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 384/833 (47%), Positives = 552/833 (67%), Gaps = 40/833 (4%)

Query  4    DFKVIEAKWQKKWEEAGVFRAEDNSDKPKFYALVEFPYPSGAGMHVGHIKAYSGLEVISR  63
            D   IE+KWQ  W +   F++  ++ KPKFYAL  FPYPSGAG+HVGH  +Y++ +++SR
Sbjct  5    DHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSR  64

Query  64   KRRMEGYNVLFPIGFDAFGLPTENYAIKTKTHPRKITDDNIVKFTEQLKKVGFSFDWSRV  123
             +R +G NVL P+G DAFGLP+E+YA+ T  +P  +T +NI +F  Q++ +GFS+DW R 
Sbjct  65   FKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDRE  124

Query  124  IDTTQEDYYKWTQWIFLKMFEKGLVFRSKALVNYCPSCKVVLSNEDS-QGGKCDICKSDV  182
            ++TT+ +YYKWTQWIF K++EKGL + +   VN        ++NE+   +G  +     V
Sbjct  125  VNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPV  184

Query  183  IQKAKDVWYLRITEYAEKLLQGLEEVDYLPNIKQQQVNWIGKSTGAFVDFLIADKEEKLR  242
            ++K+   W L+IT YAE+LL++LEEVD   +IK+ Q NWIGKSTGA V F + D +  + 
Sbjct  185  VRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFT  244

Query  243  VYTTRPDTLFGVTFMVMAPEHPLIDKYAKDISNMNEVEEYRNVCAKKTEFERTQLVKEKT  302
            V+TTRPDTLFG T+ V+APEH+L+D  +    + + V +Y+   + K+++ RT+L KEKT
Sbjct  245  VFTTRPDTLFGATYAVLAPEHALVDAITTS-DQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  303  GVRLNGIEAINPLNGKRIPIYIADYVMMGYGTGAIMAVPAHDERDYEFAKKFGIEIIEVI  362
            GV+  G  AINP+NGK +P+ IADYV+ +YGTGAIMAVPAHDERD EFAK+F ++II V+
Sbjct  304  GVW-TGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL  362

Query  363  KGGNIAEAAYTGDGEMVNSDFLNGYTNKKEAIARAIEELEKRGIGEAGVQYKMKDWAFNR  422
             GGN+ EAA+T DG  +NSDFL+G  +K  AIA+ +E LE  G+G+  V Y+++DW F+R
Sbjct  363  EGGNVEEAAFTEDGLHINSDFLDGL-DKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSR  421

Query  423  QRYWGEPIPIIHCPKCGVIPVPYEELPLRLPDIENFEPGVDGESPLAKIDSFVNCTCPKC  482
            QRYWGEPIPIIH       +VP  ELPL LP   ++ P+  GESPLA++   ++ T    
Sbjct  422  QRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDG  481

Query  483  KGAAKRETDTMPQWAGSSWYFLRYIDPNNNEALADKEKIKYWMPVDWYNGGMEHVTRHMI  542
               ++RET+TMPQWAGSSWY+LRYIDP+N E LAD E +K W+PVD Y GG EH   H++
Sbjct  482  -VKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  543  YSRFWHRFLYDIGVVNTPEPYAKRTAQGLILGPD--------------------------  576
            Y+RFWH+ LYD+GVV T EP+ K   QG+ILG                            
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  577  -------GEKMSKSKGNVVDPLDVVEVYGADVLRTYVLFMGDYASAAPWNDSAVRGCKRF  629
                     KMSKS  NVV+P DVVE YGAD LR Y +FMG   ++ +W++ ++ G ++F
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  630  LERVCSLCDIVK-GEGTTPELETSFHKTIKKVSNDYEEMKYNTAIAALMALINEIYDHGS  688
            L+RV  L       E  +  L+  ++ T+K V+++ ++MK+NTAIA LM ++N    ++ 
Sbjct  661  LDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK  720

Query  689  LTKDELVIFIKLLYPVAPHVCEEIWEKLGGEG-FLAQSSWPKYDEAKTIDKAVEIAVQIN  747
            L  D    F++L+ P APH+ EE+W+ L + G  ++  +WP YDE+K +++ VEI VQI+
Sbjct  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK  780

Query  748  GKVRGVVTIPLNCPQEEALAAAKQVPDIVPFLEGKTIVKEIYVPNKIVNIVVK  800
            GKV++ + ++ + ++EE    A     + + + GK I+K I VPNK+VNIV+K
Sbjct  781  GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

663) leuS in NC_010162


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  631 bits (2385),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 427/864 (50%), Positives = 585/864 (68%), Gaps = 75/864 (8%)

Query  30   YDHAAVEPRWQRAWEEGETFRAVRSADPARGKRYVLDMFPYPSGSGLHVGHPEGYTATDI  89
            YDH+A+EP+WQ  W + +TF++  ++D+++ K Y LDMFPYPSG+GLHVGHPEGYTATDI
Sbjct  4    YDHTAIEPKWQAFWADNHTFKT--GTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDI  61

Query  90   MSRYFRMRGIDVLHVMGWDAFGLPAEQHALETGTHPADTTARNIATFKRQLKMLGFSYDW  149
            +SR+ R +G +VLH MGWDAFGLPAEQ A++TG +PA+ TA NIA FKRQ++ LGFSYDW
Sbjct  62   LSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDW  121

Query  150  SRELSTTDPRYVRWTQWIFLQLFKKGLAYQDEVSVNWCPALGTVLANEEVI-DGKSERGS  208
             RE++TTDP Y +WTQWIF +L+ KGLAY+ EV+VNW   LGT +ANEEV+ DG SERG+
Sbjct  122  DREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGG  181

Query  209  HPVYRTPLRQWMLRITAYadrlaedlrlldWPEGTVAMQRSWIGRSEGALITFEVKGWGK  268
             PV R P+RQWML+ITAYA+RL EDL  +DWPE+   MQR+WIG+S GA +TF VK+   
Sbjct  182  YPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKD-TD  240

Query  269  GALSVFTTRPDTLMGVTYVVLAPEHPLTTWLTSAESGASEPrreavrayvaaaaGKSDRE  328
              ++VFTTRPDTL G TY VLAPEH+L   +T+++ + + +      +       KSD  
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASL------KSDLA  294

Query  329  RLAAAAREKTGVDTGLVAVHPITGVEVPIWVADYVLGGYGTGAVMAVPGHDERDFSFART  388
            R +  A+EKTGV TG  A++P+ G E+P+W+ADYVL++YGTGA+MAVP+HDERD  FA+ 
Sbjct  295  R-TDLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQ  353

Query  389  YGLPIVEVVSPDGSLHDQLEAAYVDPGVAVRSGEFDGLATEECKRAVIARLEALGRGKRE  448
            + L I+ V+  +G+++   EAA+ + G+ + S+ +DGL        ++ +LEA G G+ +
Sbjct  354  FNLDIIPVLE-GGNVE---EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNEN  409

Query  449  VNYKLRDWVFSRQRYWGEPIPIYFPVELADPQGDPRKGAAHTIRYDQPIAVDEASLPIEL  508
            V Y+LRDW+FSRQRYWGEPIPI   ++  D               + + AV E+ LP+ L
Sbjct  410  VTYRLRDWLFSRQRYWGEPIPI---IHWED---------------GTSTAVPESELPLVL  451

Query  509  PPLADFRPGDDPAGPLARAVDWRFFQRD----GKWYARETNTMPQWAGSCWYYLRFLDPQ  564
            P   D+RP++   +PLA   DW    R+    G+   RETNTMPQWAGS WYYLR++DP+
Sbjct  452  PVTKDIRPSGTGESPLANVTDWLEVTREDGVKGR---RETNTMPQWAGSSWYYLRYIDPH  508

Query  565  NDAEPFSEAAYDAWMPVDLYVGGAEHGVLHLLYARFWHKVLYDLGHVKHPEPFAKLVHQG  624
            N      E     W+PVD+YVGGAEH+VLHLLYARFWHKVLYDLG V   EPF KL +QG
Sbjct  509  NTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQG  568

Query  625  MILG---------------------------------EDNEKMSKSRGNVINPDDIVRAH  651
            MILG                                 +   KMSKS  NV+NPDD+V   
Sbjct  569  MILGTSYRDSRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQY  628

Query  652  GADVLRMYEMFMGPLEAVKPWQSGQIQGVVRFRDRVFA-TCTRPLSDAMDDATSRQLHRT  710
            GAD LR+YEMFMGPL+A  +W    ++G  +F DRV+    T+ +++   +A  +  + T
Sbjct  629  GADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALDKVYNET  688

Query  711  IKKVTGDIEGMAFNTAISAMMVFVNHLSSLPSPPREAVLRLILLVSPFAPHLAEELWR-L  769
            +K VT +++ M FNTAI+ +MVFVN  +       +    ++ L++PFAPHL+EELW+ L
Sbjct  689  VKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQAL  748

Query  770  TGHERSLSYEPWPTYDEAFCVDDVLEIPVQVNGKVRGRVMlakaaseeearaaalgleTV  829
            T+   S+SY PWP+YDE+  V++ +EI VQ++GKV++++++AK  S EE +  AL+ E V
Sbjct  749  TASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKV  808

Query  830  AALAAGKQLKKFIYVAGKIVNIVV  853
             A  AGK++ K I V+ K+VNIV+
Sbjct  809  QAEIAGKDIIKVIAVPNKLVNIVI  832

664) Desku_0441 in NC_015573


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  630 bits (2382),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 396/862 (46%), Positives = 579/862 (68%), Gaps = 71/862 (8%)

Query  6    YDFKEIEAKWQARWAAENLYKTPDFSDRPKYYCLEMFPYPSGK-LHMGHVRNYSIGDVVA  64
            YD   IE+KWQA WA ++ +KT   + +PK+Y L+MFPYPSG  LH+GH   Y+  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  65   RFKTMQGYHVLHPMGWDAFGLPAENAAIKHGNIHPADWTMDNIRTMRAQLKQLGISYDWD  124
            RFK  QG +VLHPMGWDAFGLPAE+ A+  GN +PA+ T +NI   + Q++ LG+SYDWD
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGN-DPAEFTAENIANFKRQINALGFSYDWD  122

Query  125  REVATCHPGYYKWTQWLFLQLYHKGLAYKKKAAVNWCPSCATVLANEQV-KEGACERCKT  183
            REV T +P YYKWTQW+F +LY+KGLAY    +VNW    +T +ANE+V  +G+ ER   
Sbjct  123  REVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGY  182

Query  184  PVEKRELEQWFFKITAYAERLLKDLELLKGWPEKVKIMQENWIGRSEGAEIRFKVAGMDE  243
            PV ++ + QW +KITAYAERLL DLE + +WPE +K MQ NWIG+S GA++ FKV + D 
Sbjct  183  PVVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDK  241

Query  244  EIVVFTTRPDTVFGVTYMVLAPEHPLVEKLVEGKPQAGAVRDFVRRVRNLNEIARTATDV  303
            ++ VFTTRPDT+FG TY VLAPEH+LV+ +  +  QA AV D+ R+    +++ART    
Sbjct  242  DFTVFTTRPDTLFGATYAVLAPEHALVDAITTSD-QAEAVADYKRQASLKSDLARTDLAK  300

Query  304  EKEGLFTGAYCINPLNGERVPILVANYVLLEYGTGAVMGVPAHDQRDFEFARKYNLPIRV  363
            EK G+ TG+Y INP+NG  +P+ +A+YVL  YGTGA+M+VPAHD+RD EFA+++NL I  
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  364  VIQPPGEELDPQTMTEAYAGDGVMVNSGQFNGLPKDEGIRAVIAYLEEKGLGRGQVNYRL  423
            V++    E        A++ DG+ +NS+ ++GL K  +I  ++  LE  G+G  +V YRL
Sbjct  361  VLEGGNVE------EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRL  414

Query  424  RDWLISRQRYWGAPIPIIYCDKCGIVPVPEKDLPVLLPRDVEFKP--TGQSPLADCPEFV  481
            RDWL+SRQRYWG PIPII  +     +VPE +LP++LP   +++P  TG+SPLA+  + +
Sbjct  415  RDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWL  474

Query  482  NTTCPRCGGPARRETDTMDTFMCSSWYYYRYTSPRDDRQPWDRARVDYWLPVDQYIGGVE  541
            + T    G  +RRET+TM     SSWYY RY  P++  +  D   +  WLPVD Y+GG E
Sbjct  475  EVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAE  533

Query  542  HAILHLLYSRFFTKVLYDLGLVGIQEPFTNLLTQGMVL-------------------KDG  582
            HA+LHLLY+RF  KVLYDLG+V  +EPF +L+ QGM+L                   +DG
Sbjct  534  HAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDG  593

Query  583  ---------------AKMSKSRGNVVSPEEIVAKYGADTARLFILFAAPPERDLEWSDQG  627
                           AKMSKS  NVV+P+++V +YGADT R++ +F +P +  + WS++G
Sbjct  594  SFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEG  653

Query  628  VEGCYRFLNRVWRLVASVAGRLLEAPPKPAGKLVGVNRQMHRLTHLTIKKVTEDIGNRFN  687
            +EG  +FL+RV RL+++      E     +G L       +++ + T+K VTE++ ++ +
Sbjct  654  LEGSRKFLDRVYRLITTK-----EITEENSGAL-------DKVYNETVKAVTEQV-DQMK  700

Query  688  FNTAVSAIMELVNALYQYKEVPETDRDPAVLREGIEHLLILLAPFAPHITEELWEA-TGH  746
            FNTA++ +M +VNA         ++++  ++ +    ++ L+APFAPH+ EELW+A T+ 
Sbjct  701  FNTAIAQLMVFVNA---------ANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTAS  751

Query  747  RESIHRQPWPAYDPEAIVEDEITIVVQINGRVRERVLVPADITPEQMKEVVLAQPRVQKL  806
             ESI   PWP+YD   +VE+++ IVVQI+G+V+ +++V+ D++ E+++EV LA+ +VQ  
Sbjct  752  GESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAE  811

Query  807  VEGKQIVKVIPVPGKLVNIVVK  828
            + GK+I+KVI+VP KLVNIV+K
Sbjct  812  IAGKDIIKVIAVPNKLVNIVIK  833

665) SCE1572_43065 in NC_021658


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  626 bits (2366),  Expect = 2e-180, Method: Compositional matrix adjust.
 Identities = 432/861 (51%), Positives = 583/861 (68%), Gaps = 69/861 (8%)

Query  30   YDHAAVEPRWQRAWEEGETFRAVRSAGGAREKRYVLDMFPYPSGAGLHVGHPEGYTATDI  89
            YDH+A+EP+WQ  W + +TF++  ++++++ K Y LDMFPYPSGAGLHVGHPEGYTATDI
Sbjct  4    YDHTAIEPKWQAFWADNHTFKT--GTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDI  61

Query  90   VSRYYRMRGIDVLHVMGWDAFGLPAEQHAIETGTHPADTTARNIATFKRQLKMLGFSYDW  149
            +SR+ R +G +VLH MGWDAFGLPAEQ A++TG +PA+ TA NIA FKRQ++ LGFSYDW
Sbjct  62   LSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDW  121

Query  150  SRELATTDPRYVRWTQWIFLQLFKNGLAYQDEVSVNWCPALGTVLANEEVI-DGKSERGN  208
             RE+ TTDP Y +WTQWIF +L+ +GLAY+ EV+VNW   LGT +ANEEV+ DG SERG 
Sbjct  122  DREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGG  181

Query  209  HPVYRTPLRQWMLRITAYadrlaedlrlldWPEGTVAMQRAWIGRSEGALITFEVKAWSK  268
             PV R P+RQWML+ITAYA+RL EDL  +DWPE+   MQR WIG+S GA +TF VK  + 
Sbjct  182  YPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKD-TD  240

Query  269  GAVSVFTTRPDTLMGVTYVVLAPEHPLTSWITSTEGSASEPrreavrayvaaaSSKSDRE  328
               +VFTTRPDTL G TY VLAPEH+L   IT+++ + + +       Y   AS KSD  
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVA------DYKRQASLKSDLA  294

Query  329  RLAGAAKEKTGVDTGLFAVHPITGAEVPIWVADYVLGSYGTGAVMAVPGHDERDFAFARA  388
            R ++ AKEKTGV TG +A++P+ G E+P+W+ADYVL+SYGTGA+MAVP+HDERD  FA+ 
Sbjct  295  R-TDLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQ  353

Query  389  YGLPIVEVVSPDGALHDHLEAAYVDPGVAVRSGEFDGLKTEECKRAVIERLEALGRGKRE  448
            + L I+ V+  +G ++   EAA+ + G+ + S+ +DGL        ++E+LEA G G+ +
Sbjct  354  FNLDIIPVLE-GGNVE---EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNEN  409

Query  449  VNYKLRDWVFSRQRYWGEPIPIYFPVELADPGGDPRKGDKHTIRYDQPIAVDEASlplel  508
            V Y+LRDW+FSRQRYWGEPIPI   ++  D  +                AV E+ LPL L
Sbjct  410  VTYRLRDWLFSRQRYWGEPIPI---IHWEDGTS---------------TAVPESELPLVL  451

Query  509  pplADFRPGDDPAGPLARAVDW-RFFQKDGAWYARETNTMPQWAGSCWYYLRFLDPQNDA  567
            P   D+RP++   +PLA   DW    + DG    RETNTMPQWAGS WYYLR++DP+N  
Sbjct  452  PVTKDIRPSGTGESPLANVTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTE  511

Query  568  EPFSQAAYDAWMPVDLYVGGAEHGVLHLLYARFWHKVLFDLGHVKHPEPFMKLVHQGMIL  627
                +     W+PVD+YVGGAEH+VLHLLYARFWHKVL+DLG V   EPF KL +QGMIL
Sbjct  512  KLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMIL  571

Query  628  G---------------------------------EDNEKMSKSRGNVINPDDIVRSYGSD  654
            G                                 +   KMSKS  NV+NPDD+V  YG+D
Sbjct  572  GTSYRDSRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGAD  631

Query  655  VLRLYEMFMGPLEAVKPWQSAQIQGVVRFRDRVF-ATCTRPLSDAMDDATSRQLHRTIKK  713
             LR+YEMFMGPL+A  +W    ++G  +F DRV+    T+ +++   +A  +  + T+K 
Sbjct  632  TLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALDKVYNETVKA  691

Query  714  VTGDIEAMAFNTAISAMMVFVNHLSSLPSPPREAVLRLILLVSPFAPHLAEELWR-LTGH  772
            VT +++ M FNTAI+ +MVFVN  +       +    ++ L++PFAPHL+EELW+ LT+ 
Sbjct  692  VTEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTAS  751

Query  773  QRSLAYEPWPTYDEALCVDDVLEIPVQVNGKVRGRVTLakvasedearaaalalesvaal  832
              S++Y PWP+YDE+  V++ +EI VQ++GKV++++ +AK  S +E +  ALA E V A 
Sbjct  752  GESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAE  811

Query  833  saGKQVKKFIYVPGKIVNIVV  853
             AGK++ K I VP K+VNIV+
Sbjct  812  IAGKDIIKVIAVPNKLVNIVI  832

666) leuS in NC_007644


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  625 bits (2363),  Expect = 3e-180, Method: Compositional matrix adjust.
 Identities = 381/844 (46%), Positives = 568/844 (68%), Gaps = 70/844 (8%)

Query  5    YNFKEIEPKWQRRWEASDLYRVTEDPDKPKFYCLEMFPYPSG-NLHMGHVRNYSIGDVVA  63
            Y+   IEPKWQ  W  ++ ++   D+ KPKFY L+MFPYPSG  LH+GH   Y+  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RVKRMRGYNVLHPMGWDAFGLPAENAAIHRGIPPAEWTWSNIANMRRQLHAMGISYDWDR  123
            R KR +G NVLHPMGWDAFGLPAE+ A++ G  PAE T  NIAN +RQ++A+G+SYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVATCHPNYYRWTQWLFLQMYKHGLAYRKKAAVNWCPSCATVLANEQVV-DGACERCHTP  182
            EV T +PNYY+WTQW+F ++Y  GLAY    +VNW    +T +ANE+V+ DG+ ER   P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VMRKDLEQWFFRITDYADRLLEDLKKLPGWPDKVKIMQENWIGKSSGAEVVFRVEGSGEE  242
            V+RK + QW ++IT YA+RLLEDL  + +WP+ +K MQ NWIGKS+GA+V F+V +++ +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  IPVFTTRPDTLYGVTYLVLAPEHPLVEKLTAGTPYEGPVEEFVQAARYLSALDRTATEKE  302
            + VFTTRPDTL+G TY VLAPEH+LV+ +T++     +V ++ + A   S L RT   KE
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQ-AEAVADYKRQASLKSDLARTDLAKE  301

Query  303  KEGLFTGAYAINPVNNERVPIWIANYVLMEYGTGAVMGVPAHDQRDFEFARKYDLPVKVV  362
            K G+ TG+YAINPVN   +P+WIA+YVL  YGTGA+M+VPAHD+RD EFA++++L +  V
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  363  IRPASSELPAGELAAAYVEDGIMVNSGPFNGLPNREGIQKVTEYLESIGRGRARVNYRLR  422
            +  ++ E       AA+ EDG+ +NS+ ++GL +  +I K+ E LE+ G G   V YRLR
Sbjct  362  LEGGNVE------EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  423  DWLISRQRYWGAPIPMIYCDQCGIVPVPEEDLPVILPEGVEFRP--TGESPLTYCPEFVN  480
            DWL+SRQRYWG PIP+I  ++    +VPE +LP++LP   ++RP  TGESPL+   + ++
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  481  TTCPRCGGPARRETDTMDTFVCSSWYFLRYTSPHSQDRAFERDKVDYWMNVDQYIGGVEH  540
             T    G  +RRET+TM     SSWY+LRY  PH+ ++  + + +  W+ VD Y+GG EH
Sbjct  476  VTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEH  534

Query  541  AILHLMYARFFTKALHDFGLVGVEEPFQNLLTQGMVL-------------------KDGS  581
            A+LHL+YARF  K L D+G+V   EPFQ+L+ QGM+L                   +DGS
Sbjct  535  AVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGS  594

Query  582  ---------------KMSKSKGNIVSPEEIINRYGADTARLFILFAAPPERDLEWSDQGV  626
                           KMSKS  N+V+P++++++YGADT R++ +F +P +  + WS++G+
Sbjct  595  FFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGL  654

Query  627  EGCYRFLNRVWRLVGSYADAVRRAGGSLEIRSHADRELWRLLHATIKKVTEDVEERFNFN  686
            EG  +FL+RV RL+ +  +     +G+L+          ++ + T+K VTE+V++  +FN
Sbjct  655  EGSRKFLDRVYRLITT-KEITEENSGALD----------KVYNETVKAVTEQVDQ-MKFN  702

Query  687  TAISAIMELVNGCYRYQDTVPEEEQNLVLMGEVLRKLVTLLAPFAPHITEELWQGL-GGQ  745
            TAI+ +M +VN+  +       E++   L ++  + +V L+APFAPH+ EELWQ+L ++ 
Sbjct  703  TAIAQLMVFVNAANK-------EDK---LFSDYAKGFVQLIAPFAPHLGEELWQALTASG  752

Query  746  ESVHRESWPQYDPEALVEEEITLVIQINGKVKDRMQVPAGLAREKIEELVLNRDKVAALL  805
            ES+   +WP YD   LVE+++ +V+QI+GKVK ++ V+ +L+RE ++E+ L  +KV A +
Sbjct  753  ESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEI  812

Query  806  AGQQ  809
            AG++
Sbjct  813  AGKD  816

667) RTO_26330 in NC_021015


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  624 bits (2358),  Expect = 7e-180, Method: Compositional matrix adjust.
 Identities = 403/843 (48%), Positives = 567/843 (68%), Gaps = 52/843 (6%)

Query  7    YNHKAIEKKWREKWEETPVNPRNGKDGNKKPKYYCLDMFPYPSGNGLHVGHWRGYVISDV  66
            Y+H AIE KW+  W +     + G D++K PK+Y LDMFPYPSG GLHVGH  GY  +D+
Sbjct  4    YDHTAIEPKWQAFWADNHTF-KTGTDASK-PKFYALDMFPYPSGAGLHVGHPEGYTATDI  61

Query  67   WSRYKLQQGYYIVHPMGWDAFGLPAENYAIKMGVHPAKSTEANITNIKRQINDIAALYDW  126
             SR+K  QG  ++HPMGWDAFGLPAE+YA+  G +PA  T  NI+N+KRQIN ++  YDW
Sbjct  62   LSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDW  121

Query  127  DMEVNTTDPEFYKWTQWIFVKMFKEGLAYEKEFPINWCPSCKTGLANEEVV-NGKCERCG  185
            D EVNTTDP++YKWTQWIF K++  GLAYE E P+NW     T++ANEEV+ +G  ER G
Sbjct  122  DREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGG  181

Query  186  AEVTKKNLRQWMLRITKYADRLLNDLDKLDWPEKVKKMQADWIGKSYGAEVDFPVEGRDE  245
              V +K +RQWML+IT YA+RLL+DL+ +DWPE +K MQ +WIGKS GA+V F V + D 
Sbjct  182  YPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDK  241

Query  246  KITVYTTRPDTLHGATFMVLAPEHELAASLATDETRDAVEKYIYDASMKSNVDRMQ-DKE  304
             +TV+TTRPDTL GAT+ VLAPEH L  +++T +  +AV  Y  +AS+KS++ R +  KE
Sbjct  242  DFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKE  301

Query  305  KTGVFTGSYAINPLNGAKTPIWLSDYVLADYGTGAIMCVPAHDDRDFEFATKFNIPIIQV  364
            KTGV TGSYAINP+NG   P+W++DYVLA YGTGAIM VPAHD+RD EFA +FN+ II V
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  365  IAKDGEEIENMTEAYTDAVGTMINSGEWNGMESSVLKKEAPHMIEEMGIGRATVNYKLRD  424
            +  +G ++E+   A+T+  G  INS+  +G++ +       + +E  G+G   V Y+LRD
Sbjct  362  L--EGGNVEE--AAFTED-GLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  425  WVFSRQRYWGEPIPIIHCPKCGNvpvpeeelplrlpevDSYEPTGTGESPLAAIDEWVNC  484
            W+FSRQRYWGEPIPIIH     + +VPE ELPL LP      P+GTGESPLA + +W++ 
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  485  KCPVCGSDSKRETNTMPQWAGSSWYFLRYVDNHNSEALVSREKADEMLPVDMYIGGVEHA  544
                 G  ++RETNTMPQWAGSSWY+LRY+D HN+E L   E   + LPVD+Y+GG EHA
Sbjct  477  TRE-DGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  545  VLHLLYSRFYTKFLCDIGAIDFDEPFHKLFNQGMITG-----------------------  581
            VLHLLY+RF  K L D+G +   EPF+KLFNQGMI G                       
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSF  595

Query  582  ----------KNGIKMSKSKGNVVSPDDLVRDYGCDSLRMYELFVGPPELDAEWDDRGID  631
                      +   KMSKS  NVV+PDD+V +YG D+LR+YE+F+GP +    W + G++
Sbjct  596  FHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLE  655

Query  632  GVNRFLKRLWNILMESKEKDVQPTKEMIKLRHRMVYDITTRLESFSLNTVISGFMEYNNK  691
            G  +FL R+   L+ +KE   + +  + K+ +  V  +T +++   +NT I+ +M     
Sbjct  656  GSRKFLDRVYR-LITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMV----  710

Query  692  FMEIAKKEGGIDKETLETIAVLLSPFAPHFAEEMWEQL-GHEETIFNAGWPKYDENEMKD  750
            F++ A+KE+ +  +    +  L++PFAPH++EE+W+ L +  E+I    WP YDE+ + +
Sbjct  711  FVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVE  770

Query  751  DEIKIPVQINGKTKAVIEIPADISKDD--AIAAGKEAIADKLTG-NVIKEIYVPKKIINI  807
            +++ I VQI+GK KA + ++ D+S+++   +A ++E +   ++G ++IK I VP+K++NI
Sbjct  771  NDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNI  830

Query  808  VMK  810
            V+K
Sbjct  831  VIK  833

668) Desca_1898 in NC_015565


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  624 bits (2357),  Expect = 8e-180, Method: Compositional matrix adjust.
 Identities = 383/864 (45%), Positives = 583/864 (68%), Gaps = 75/864 (8%)

Query  5    YDFKEIEAKWQQYWEKQNIYQVPDYSDRPKYYCLEMFPYPSGK-LHMGHVRNYSIGDVVA  63
            YD   IE+KWQ +W  ++ ++    + +PK+Y L+MFPYPSG  LH+GH   Y+  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RFKNMQGYHVLHPMGWDAFGLPAENAAIKNGIPPATWTWDNIAHMRSQLKQLGLSYDWQR  123
            RFK  QG +VLHPMGWDAFGLPAE+ A+  G  PA  T +NIA+ + Q++ LG+SYDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVATCHPEYYKWGQWLFLQLYKRGLCYKKHARVNWCPDCATVLANEQVV-EGGCERCGAT  182
            EV T +P+YYKW QW+F +LY +GL Y  +  VNW  + +T +ANE+V+ +G  ER G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VEQRELDQWFFRITDYAQRLLDDLKLLEGWPDKVKIMQENWIGRSEGAELTFKVEGSDDE  242
            V ++ + QW ++IT YA+RLL+DL  ++ WP+ +K MQ NWIG+S GA++TFKV ++D +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  ITVFTTRPDTVYGVTYMVLAAEHPLVAKLSAGKPQEAQVAEFVNRVGKLTELART--SNE  300
            +TVFTTRPDT++G TY VLA+EH+LV  ++++   EA VA++  + +  ++LART  ++E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEA-VADYKRQASLKSDLARTDLAKE  301

Query  301  KEGVFIGAYCINPFNGDKVPILAANYVLYHYGTGAVMGVPAHDERDFEFARKYNLPIKPV  360
            K GV  G+Y INP NG  +P+  A+YVL  YGTGA+M+VPAHDERD EFA+++NL I PV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  361  IKPVNGEELVAENMTEAYTGPGVMVNSGPFDGTPNQQGIKKVIEYAEQKGIGRGLVNFRL  420
            +   N EE        A+T  G+ +NS+ +DG  +  +I K++E  E  G+G   V +RL
Sbjct  362  LEGGNVEE-------AAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRL  414

Query  421  RDWLISRQRYWGTPIPIMYCDKCGVVPVPEDQLPVLLPTDVAFKP--TGESPLKGDPEFV  478
            RDWL+SRQRYWG PIPI+  +     +VPE +LP++LP    ++P  TGESPL    + +
Sbjct  415  RDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWL  474

Query  479  HTTCPQCGGPAQRETDTMDTFVDSSWYYLRYTSPRDTEQAWDKQKANHWMSVDQYIGGVE  538
            + T  + G  ++RET+TM    +SSWYYLRY  P++TE+  D +  ++W++VD Y+GG E
Sbjct  475  EVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAE  533

Query  539  HAILHLLYSRFFTKVFYDLGLVDVQEPFKNLLTQGMVL-------------------KDG  579
            HA+LHLLY+RF  KV+YDLG+V  +EPF++L+ QGM+L                   +DG
Sbjct  534  HAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDG  593

Query  580  ---------------AKMSKSKGNVVSPEEIVDRYGADTARLFILFAAPPERDLEWSDRG  624
                           AKMSKS  NVV+P+++V++YGADT R++ +F +P +  + WS+ G
Sbjct  594  SFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEG  653

Query  625  VEGSHRFLNRVWRLVYSVKDEVAAAPAIDPKANFVGVHKEMRRLTHYAIKKVTEDVSGRF  684
            +EGS++FL+RV RL+ + K+     ++             + ++ + ++K VTE+V ++ 
Sbjct  654  LEGSRKFLDRVYRLI-TTKEITEENSG------------ALDKVYNETVKAVTEQV-DQM  699

Query  685  NFNTAISTIMELVNGIYTYRDKVAAVERNSSVLAEAINSMIILLAPFAPHISEELWAA-T  743
            +FNTAI+ +M +VN          A +++  ++++  ++ + L+APFAPH++EELW A T
Sbjct  700  KFNTAIAQLMVFVN----------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALT  749

Query  744  GHKESVHKQPWLVYDPAALVEDEVEIVVQINGKVRDRMNIPAGLSAAEMQQVVLAKDSVQ  803
            +  ES+   PW  YD + LVE++VEIVVQI+GKV+ ++ ++ +LS  E+Q+V LA++ VQ
Sbjct  750  ASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQ  809

Query  804  QLISGKQVVKIIPVPGKLINIVVK  827
              I+GK+++K+I+VP KL+NIV+K
Sbjct  810  AEIAGKDIIKVIAVPNKLVNIVIK  833

669) Slip_1669 in NC_014220


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  623 bits (2353),  Expect = 2e-179, Method: Compositional matrix adjust.
 Identities = 380/860 (45%), Positives = 576/860 (67%), Gaps = 69/860 (8%)

Query  5    YNFKTVEAKWQNFWEENGFYIVTEDKTKPKYYDLEMFPYPSG-NLHMGHVRNYAIGDVVA  63
            Y+  ++E+KWQ FW +N  +    D +KPK+Y L+MFPYPSG  LH+GH   Y+  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RFKTMNGYNVLHPMGWDAFGLPAENAAIKHGIHPSIWTDSNIENMKRQLKSLGISYDWTR  123
            RFK  +G NVLHPMGWDAFGLPAE+ A+  G +P+  T  NI N KRQ+++LG+SYDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EFATCKPEYYRFTQWLFLKLYENGLAYKKKAAVNWCPSCATVLANEQVV-DGDCERCGTR  182
            E  T  P+YY+ TQW+F KLYE+GLAY    +VNW    +T +ANE+V+ DG  ER G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VEKKSLEQWFFKITDYAERLLNDLDKLPGWPEKVKIMQKNWIGRSEGCEFSLAIDGSAET  242
            V +K++ QW +KIT YAERLL+DL+ + +WPE +K MQ+NWIG+S G + ++ + ++   
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  VSVFTTRPDTVFGITYMVLAPEHPLVEKLTRDTPYQQAVDEFIHRMKFLNEIDRTSTETE  302
             +VFTTRPDT+FG TY VLAPEH+LV+ +T      +AV ++ ++  + +++ RT    E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQ-AEAVADYKRQASLKSDLARTDLAKE  301

Query  303  KEGVFAGAYAVNPVNGEKVPIWIANYVLMEYGTGAIMAVPAHDQRDFEFARKYGLPVRVV  362
            K GV +G+YA+NPVNG  +P+WIA+YVL  YGTGAIMAVPAHD+RD EFA+++ L +  V
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  363  IEPEGMSLDPDVMTAAYEGGGVMVNSGQFDGLGNEDGKQKVIEWMEDRGIGRRAVNYRLR  422
            +E      + +V  AA+  +G+ +NS+ +DGL++  +  K++EW+E  G+G   V YRLR
Sbjct  362  LE------GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  423  DWLISRQRYWGAPIPIVYCDNCGPQSVPYEQLPVMLPLNVEFRP--TGESPLTYVDEFVN  480
            DWL+SRQRYWG PIPI+  ++  + +VP  +LP++LP+  ++RP  TGESPL+ V + ++
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  481  TECPSCGGPAKRETDTMDTFVCSSWYYFRYCSPHVQDRPWDKEAVDYWMPVDQYIGGVEH  540
                  G  ++RET+TM     SSWYY+RY  PH  ++  D E +  W+PVD Y+GG EH
Sbjct  476  V-TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEH  534

Query  541  AILHLMYSRFFTKVLYDLGLVSCEEPFTNLLTQGMVL-------------------KDG-  580
            A+LHL+Y+RF  KVLYDLG+V+  EPF +L+ QGM+L                   +DG 
Sbjct  535  AVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGS  594

Query  581  --------------AKMSKSKGNTVSPEDIINTYGADTARLFILFASPPEKDLEWSDQGV  626
                          AKMSKS  N V+P+D+++ YGADT R++ +F +P +  + WS++G+
Sbjct  595  FFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGL  654

Query  627  EGCYRFLNRVWRLVAEYSNQVRGVEAYGGGSNLSAADRELRYRTHFTIKKVTEDIEKRFN  686
            EG  +FL+RV RL++  ++++        ++ L        Y    T+K VTE+++ + +
Sbjct  655  EGSRKFLDRVYRLIT--TKEITE----ENSGALDKV-----YNE--TVKAVTEQVD-QMK  700

Query  687  FNTAISAIMELVNALYQYKDNEHQNlavvkealkalvlvlSPFSPHIAEELWEAIGGEG-  745
            FNTAI+ +M +VNA        +++  +  +  K++V +++PF+PH++EELW+A+ + G 
Sbjct  701  FNTAIAQLMVFVNA-------ANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGE  753

Query  746  SVHQQQWPKYDEEALVKDEIEIVVQINGKVRERAMVPSGAGPDEMKTVAMSLDRIQEMLA  805
            S+    WP YDE  LV +++EIVVQI+GKV+ + +V+ + + +E++ VA++ +++Q  +A
Sbjct  754  SISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIA  813

Query  806  GKTVRKVIAVPGKLVNIVVN  825
            GK + KVIAVP KLVNIV++
Sbjct  814  GKDIIKVIAVPNKLVNIVIK  833

670) CL2_10680 in NC_021016


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  620 bits (2343),  Expect = 1e-178, Method: Compositional matrix adjust.
 Identities = 420/840 (50%), Positives = 567/840 (68%), Gaps = 51/840 (6%)

Query  5    YNHKAIEQKWRKHWQEHPV--NVNDGKKPKYYCLDMFPYPSGSGLHVGHWRGYVISDVWS  62
            Y+H AIE KW+  W ++       D+ KPK+Y LDMFPYPSG+GLHVGH  GY  +D+ S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKLLNGYYVIHPMGWDAFGLPAENYAIKMGTHPRISTEANIKNIKRQINEISAIYDWDM  122
            R+K  +G  V+HPMGWDAFGLPAE+YA+  G +P   T  NI N+KRQIN ++  YDWD 
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVNTTDPEFYKWTQWIFVKMFKKGLAYEKQMPINWCPSCKTGLANEEVV-NGKCERCGAD  181
            EVNTTDP++YKWTQWIF K++ KGLAYE ++P+NW     T++ANEEV+ +G  ER G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VTKKNLRQWMLKITayadrlladldkldWPEKVKKMQAEWIGKSHGAEVNFKVDGRDDEI  241
            V +K +RQWMLKITAYA+RLL DL+ +DWPE +K MQ +WIGKS GA+V FKV + D ++
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  TVYTTRPDTLHGATFMVLAPEHELAKDLATDETREAVEEYIYQASLKSSVDRMQ-DKEKT  300
            TV+TTRPDTL GAT+ VLAPEH L   ++T +  EAV +Y  QASLKS + R +  KEKT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  301  GVFTGSYAINPINGAKVPIWLSDYVLADYGTGAIMCVPAHDDRDFEFAKKFDIPIIQVIA  360
            GV TGSYAINP+NG  +P+W++DYVLA YGTGAIM VPAHD+RD EFAK+F++ II V+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL-  362

Query  361  KDGKEIENMEEAYTEASGIMINSGDWNGKESSELKEEAPKIIEEMGIGKKTTNYKLRDWV  420
             +G ++E  E A+TE  G+ INS+  +G + +         +E  G+G+    Y+LRDW+
Sbjct  363  -EGGNVE--EAAFTE-DGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWL  418

Query  421  FSRQRYWGEPIPIVHCPDCGAvpvpeeelpltlpeveKYEPTGTGESPLADIEDWVNCKC  480
            FSRQRYWGEPIPI+H  D  + +VPE ELPL LP      P+GTGESPLA++ DW++   
Sbjct  419  FSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTR  478

Query  481  PVCGKDAKRETNTMPQWAGSSWYFLRYIDNKNNEELVSREKADKYLPVDMYIGGVEHAVL  540
                K ++RETNTMPQWAGSSWY+LRYID  N E L   E   + LPVD+Y+GG EHAVL
Sbjct  479  EDGVK-GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVL  537

Query  541  HLLYSRFYTKFLCDIGVIDFDEPFHKLFNQGMITG-------------------------  575
            HLLY+RF  K L D+GV+   EPF+KLFNQGMI G                         
Sbjct  538  HLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFH  597

Query  576  --------KNGIKMSKSKGNVVSPDDLVRDYGCDSLRMYELFVGPPELDAEWDESGIDGV  627
                    +   KMSKS  NVV+PDD+V +YG D+LR+YE+F+GP +    W E G++G 
Sbjct  598  VETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGS  657

Query  628  HRFLTRFYKLIMDQKDKGVEADKELLKVRHKLIYDITTRLNNFSLNTVVSGFMEYTNTLT  687
            ++FL R Y+LI   K+   E    L KV +  +  +T ++++  +NT ++ +M + N   
Sbjct  658  RKFLDRVYRLITT-KEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVN---  713

Query  688  AMAKKSGVDKETLETAIVLLAPFAPHIAEELWEAM-GHEDSVFAQTWPTYDEEAMKEDEV  746
            A  K   +  +     + L+APFAPH++EELW+A+ +  +S+    WP+YDE  + E++V
Sbjct  714  AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDV  773

Query  747  EIVVQINGKVKGKLVVGAEEDKDSV--LAKAKEVLGDKLNG-NIVKEIYVPGRIVNIVQK  803
            EIVVQI+GKVK+KLVV+ +  ++ +  +A A+E +   + G +I+K I VP ++VNIV K
Sbjct  774  EIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

671) RUM_13040 in NC_021039


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  619 bits (2340),  Expect = 2e-178, Method: Compositional matrix adjust.
 Identities = 419/838 (50%), Positives = 572/838 (69%), Gaps = 41/838 (4%)

Query  1    MSKYDFTAIEKKWQKYWEEHHTFAAGTDYSKPKFYALVEFPYPSGQGLHIGHPRPYTAMD  60
            M+ YD TAIE KWQ +W ++HTF +GTD SKPKFYAL  FPYPSG GLH+GHP  YTA D
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   IVSRKRRLEGYNVLFPMGWDAFGLPTENYAIKNKIHPAIVTKNNIAHFKAQLQSLGLSFD  120
            I+SR +R +G NVL PMGWDAFGLP+E+YA+    +PA  T +NIA+FK Q+++LG+S+D
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WDREINTTDPEYFKWTQWIFLQMFKKGLAYKKEMSVNWCTSCKVVLANeevvggvcercg  180
            WDRE+NTTDP+Y+KWTQWIF +++ KGLAY  E++VNW       +ANEEV+ +     G
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  181  g-evIHKVKSQWMLKITEYAQRLLDDLAEVNYLDKIKATQINWIGRSTGAEVDFttttge  239
            G  V++K   QWMLKIT YA+RLL+DL EV+  + IK  Q NWIG+STGA+V F     +
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  240  tl-tvyttRPDTLFGATYMVISPEHPYIEKWADKLSNMEEIRAYQEKAARKSDFERTEMA  298
               TV+TTRPDTLFGATY V++PEH+ ++       + E +  Y+ +A+ KSD+ RT++A
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDA-ITTSDQAEAVADYKRQASLKSDLARTDLA  299

Query  299  KDKTGVELKGIRAINPVNGREIPIFISDYVLMTYGTGAIMAVPAHDTRDYDFAKVFHLPI  358
            K+KTGV   G  AINPVNG+E+P+ I+DYVL +YGTGAIMAVPAHD RD +FAK F+L I
Sbjct  300  KEKTGV-WTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDI  358

Query  359  IEVVAGGDIEKEAFTDCATGKMVNSGFLDGLSVEEAKVKIKEWLKENGKGHEKVNYKLRD  418
            I V+ GG++E  AFT+   G  +NS+FLDGL    A  K+ EWL  +G G+E+V Y+LRD
Sbjct  359  IPVLEGGNVEEAAFTE--DGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  419  WVFSRQRYWGEPIPIVYCEKCGYVplpeselpltlpeVDSYMPTDNGESPLSTLDSFINT  478
            W+FSRQRYWGEPIPI+  E     ++PESELPL LP      P++ GESPL+ +   ++ 
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  479  TCPHCGGPAKRETDTMPQWAGSSWYYLRYCDPKNKECLASKEALDYWMPVDWYNGGMEHT  538
            T  + G  ++RET+TMPQWAGSSWYYLRY DP N E LA  E L  W+PVD Y GG EH+
Sbjct  477  TRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  539  TLHLLYSRFWHKFLYDIGAVSQKEPYMRRTSHGMILG-----------------------  575
             LHLLY+RFWHK LYD+G V+ KEP+ +  ++GMILG                       
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSF  595

Query  576  ----------EDGQKMSKSRGNVINPDEVVAQYGADTLRLYEMFIGDFEKTAPWSPSSIR  625
                      +   KMSKS  NV+NPD+VV QYGADTLR+YEMF+G ++ + +WS  ++ 
Sbjct  596  FHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLE  655

Query  626  GCKRFLDRVWALQDMLTDGEEYRPETRALMHKTIKKVSEDIENLKFNTAIASMMALINEI  685
            G ++FLDRV  L       EE       + + T+K V+E+++++KFNTAIA +M ++N  
Sbjct  656  GSRKFLDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAA  715

Query  686  YALGSINRAELRTlllllNPFAPHMTEEMYE-VQNLGGVLNEQKWPTFDPALCVDEMVEL  744
               + +     + ++ L+ PFAPH+ EE+ + +   G  ++   WP++D +  V++ VE+
Sbjct  716  NKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEI  775

Query  745  VVQINGKVRSKLQVPVDSAQADVLEKAKAEPKIQDALQGKQIVKEIYVQNKLVNFVAK  802
            VVQI+GKV++KL V+ D ++ ++ E A A+ K+Q  + GK+I+K I V NKLVN+V K
Sbjct  776  VVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

672) leuS in NC_017503


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  619 bits (2339),  Expect = 2e-178, Method: Compositional matrix adjust.
 Identities = 389/854 (46%), Positives = 572/854 (67%), Gaps = 74/854 (8%)

Query  2    YNHNLIEKKWAKIWNDQKVYSFQIDKNKPKYYILDMFPYPSGKGLHVGHVKAYMATDVIS  61
            Y+H  IE KW  +W D+  +    D +KPK+Y LDMFPYPSG GLHVGH  +Y ATD++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  62   RWKNALGFNVLHPIGWDAFGLPAEQYAIQTNNHPAKFTQENINNFRTQLKRLGFNYDYRL  121
            R K A G NVLHP+GWDAFGLPAEQYA++T N+PA FT ENI NF+ Q++ LGF+YD   
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  122  EVDTTNKNYFKWTQWIFKKLYEHDLAYQADIEVNWCEQLGTVLANEEVLTDENGNKISER  181
            EV+TT+ NY+KWTQWIF KLYE +LAY+A++ VNW E+LGT +ANEEVL D      SER
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGT----SER  179

Query  182  GSYPVIKKKMRQWVLKITAFADQLIDGLENLNWPNSIKAMQVNWINKSVGASIKFEIDQL  241
            G+YPV++K MRQW+LKITA+A++L+++LE+++WP+SIK MQ NWI KS GA++ F + + 
Sbjct  180  GGYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDT  239

Query  242  DNQTIEVFSSRVDTLFGASFIALSFDHPLVKQKLITDKNDAIERFIKDNSIDQTV-RYQ-  299
            D++ + VF++R DTLFGA++  L+ +H+LV     +D+ +A+  + ++ S+   + R + 
Sbjct  240  DKD-FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDL  298

Query  300  -----GINTNYFAIHPITKKKIPIYLADYILSDYGTGAVMGVPAHDDRDYQFAKQYDLEI  354
                 G+ T  +AI+P+  K +P+ +ADY+L+ YGTGA+M+VPAHD+RD +FAKQ++L+I
Sbjct  299  AKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDI  358

Query  355  IPVIKA---DQYPYLLDGEHINSDFNNGLNNEQAIQKTIAYLKKHNLGDQKINYKLRDWI  411
            IPV+ +   ++ ++  DG HINSDF +GL++  AI K +  L  + +G++++ Y+LRDW+
Sbjct  359  IPVLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWL  418

Query  412  FSRQRYWGEPFPVLFDEEDNIYLLKDSELPLELPQLSDFSPNKDGLPPLANADDQWLHPI  471
            FSRQRYWGEP+P++  E++    + +SELPL LP   D+ P+  G +PLAN  D WL+  
Sbjct  419  FSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTD-WLEVT  477

Query  472  IDQK-KYRREINTMPQWAGSCWYYLAYLLKLTDLNQADGDQNYLALNSEKAKELFDHFMP  530
             ++  K RRE NTMPQWAGS WYYL Y+          + +N   L  E   EL+ + +P
Sbjct  478  REDGVKGRRETNTMPQWAGSSWYYLRYI----------DPHNTEKLADE---ELLKQWLP  524

Query  531  VDLYVGGQEHAVLHLLYARFWYKFLHQIKIVSSTEPFSKLINQGMILG------------  578
            VD+YVGG EHAVLHLLYARFW K L ++ +V++ EPF KL+NQGMILG            
Sbjct  525  VDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVA  584

Query  579  ---------------------EDNTKMSKSKGNIINPDDLVLSHGADTIRTYVMFMGPln  617
                                 +  +KMSKS  N++NPDD+V   GADT+R Y MFMGPL+
Sbjct  585  TDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLD  644

Query  618  aslawnsnalnGTRKFLERVYNLFDRVEINDSINQNLNYDYHNFLKKINKHLENFEFNLV  677
            AS+AW+ ++L+G+RKFL+RVY L+   EI +  +  L+  Y++ +K +  ++++  FN  
Sbjct  645  ASIAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTA  704

Query  678  VSEMMIFINACYKQTQINKEMITNFLIVLSFFAPYLAEELNSKLNNPTLLYKMRLAQW--  735
            ++++M+F+NA  K+ ++  +    F+ +++ FAP L+EEL   L  +     +    W  
Sbjct  705  IAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGE--SISYVPWPS  762

Query  736  -DEAYLVKNTTTISCSINGKF--KLVHEFDLDSDE-QEVANYFLNQDLIKRNLEDKKLVK  791
             DE+ LV N   I   I+GK   KLV   DL  +E QEVA   L ++ ++ ++ +K ++K
Sbjct  763  YDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVA---LANEKVQAEIAGKDIIK  819

Query  792  TIFVKNKVINFIIK  805
             I V NK++N++IK
Sbjct  820  VIAVPNKLVNIVIK  833

673) leuS in NC_016048


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  619 bits (2337),  Expect = 3e-178, Method: Compositional matrix adjust.
 Identities = 401/845 (48%), Positives = 570/845 (68%), Gaps = 56/845 (6%)

Query  3    YDFTSIEKKWQDKWLKEKPFAAVNGDTTRPKFYGLIEFPYPSGQGLHVGHPRPYTAMDII  62
            YD T+IE KWQ  W  +  F +   D+++PKFY+L  FPYPSG GLHVGHP  YTA DI+
Sbjct  4    YDHTAIEPKWQAFWADNHTFKT-GTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDIL  62

Query  63   CRKKRMQGYNVLFPIGFDAFGLPTENYAIKMHIHPRKVTEDNIANFRKQIQSLGYSFDWD  122
             R KR QG NVL P+G DAFGLP+E+YA+    +P   T +NIANF++QI++LG+S+DWD
Sbjct  63   SRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWD  122

Query  123  REVDTTDPSYYKWTQWIFLQMYKKGLAYKTTMPVNWCTSCKCVLANeevvegvcercgS-  181
            REV+TTDP+YYKWTQWIF ++Y KGLAY + +PVNW       +ANEEV+ +     G+ 
Sbjct  123  REVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGY  182

Query  182  AVIRKEKSQWMLKITEYAQrliddlddvdfidrvKIQQRNWIGRSEGTEVDFTATNGDR-  240
            +V+RK   QWMLKIT YA+RL++DL++VD  + +K  QRNWIG+S G++V F   + D+ 
Sbjct  183  PVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  241  LTVYTTRCDTLFGVTYMVLSPEHEYLKKWKDQIKNWDEVAGYMDAAARKSDLERTELNKE  300
            +TV+TTR DTLFG TY VL+PEH  +       +  + VA+Y   A+ KSDL RT+L KE
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQA-EAVADYKRQASLKSDLARTDLAKE  301

Query  301  KTGVRLEGIEAMNPVTGEKLPVFVSDYVLITYGTGIVMGVPGHDQRDWEFAKKFNLPIVE  360
            KTGV+  G  A+NPV G  +PV ++DYVL +YGTG +M+VP+HD+RDWEFAK+FNL I+ 
Sbjct  302  KTGVW-TGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  361  VVKGGDITKEAFALKDDTGILVNSGFLSGKTVKEAIPAMKQWVTEKGIGRPKINYKLRDW  420
            V+ GG++   AF+   + G+ +NS+FL G     AI+ M +W+   G+G  ++ Y+LRDW
Sbjct  361  VLEGGNVEEAAFT---EDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDW  417

Query  421  VFSRQRYWGEPIPMVKCEKCGWVplpedqlplllpNVENYEPTDDGESPLSAMTDWVNTT  480
            +FSRQRYWGEPIP++  E     ++PE +LPL+LP   +  P++ GESPL+ +TDW++ T
Sbjct  418  LFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT  477

Query  481  CPCCGGTAKRETDTMPQWAGSSWYFLRYMDPHNDKALASKEALEYWSPVDWYNGGMEHTT  540
                G  ++RET+TMPQWAGSSWY+LRY+DPHN   LA  E L  W PVD Y GG EH+ 
Sbjct  478  RE-DGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  541  LHLLYSRFWHKFLYDIGVVPTKEPYQKRTSHGMILG------------------------  576
            LHLLY+RFWHK LYD+GVVPTKEP+QK  ++GMILG                        
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFF  596

Query  577  ---------EGGEKMSKSRGNVVNPNDIVEQYGADTMRLHIMFIGDFEKAVTWSNEAVKG  627
                     ++  KMSKS  NVVNP+D+VEQYGADT+R+  MF+G ++ +++WS+E++ G
Sbjct  597  HVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEG  656

Query  628  SKRFLDRVWNLSESASDSYEMTPANESIIHKTIKKVTEDIDELKMNTAISSMMTMVNEFY  687
            S++FLDRV  L  +   + E + A + + + T+K VTE++D++K NTAI+ +M      +
Sbjct  657  SRKFLDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMV-----F  711

Query  688  ANGVSRGDMKY------LLLLLSPFAPHISEELWENLGFARMTGKMACQNEWPSFDESKT  741
             N+ ++ D  +      ++ L++PFAPH++EELW+ L     +G       WPS+DESK 
Sbjct  712  VNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALT---ASGESISYVPWPSYDESKL  768

Query  742  AAATVEMAVQVGGKLKGTVILPTDSDEDTVKTAALKVEKVHKSTEGMQIVKTIYIKNRLI  801
                VE+ VQ+ GK+K+ ++++ D   + ++  AL  EKV+    G +I+K I + N+L+
Sbjct  769  VENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLV  828

Query  802  NLIVK  806
            N+++K
Sbjct  829  NIVIK  833

674) HMPREF0389_00536 in NC_016630


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  618 bits (2336),  Expect = 4e-178, Method: Compositional matrix adjust.
 Identities = 368/835 (45%), Positives = 556/835 (67%), Gaps = 40/835 (4%)

Query  4    YNPNQIEKKWQSHWEKNHTFRSEIDHNKKKYFNLIEFPYPSGAGLHVGHIRAYTSLEVIS  63
            Y+   IE KWQ+ W  NHTF++  D +K K++ L  FPYPSGAGLHVGH  +YT+ +++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RKRRLEGYNVLFPIGWDAFGLPTENYAMQTGEHPRTVTDRNIEVFTDQLKSAGYSFDWER  123
            R +R +G NVL P+GWDAFGLP+E+YAM+TG++P   T  NI  F  Q+++ G+S+DW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  TIDTTDPNYYKWTQWIFLQMFKHKLAYKDTTYVNFCNNCKVVLANEES-QNGVCDRCGHD  182
             ++TTDPNYYKWTQWIF +++   LAY     VN  ++    +ANEE   +G  +R G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VVQMEKDVWFLKIREYADKLLDGLEELDFLPRIKLEQENWIGRSNGAEVNFPISGTEDFL  242
            VV+     W LKI  YA++LL++LEE+D    IK  Q NWIG+S GA+V F + +T+  +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  243  RIYTTRPDTIFGVTFMVMAPEHPYLKKYEAKLQNLDEIKDYQEQATRKTEFERVQLAKDK  302
             ++TTRPDT+FG T+ V+APEH+ +    +  ++ + + DY+ QA+ K+++ R +LAK+K
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTS-DQAEAVADYKRQASLKSDLARTDLAKEK  302

Query  303  TGVEIKGLTVINPLTKKEIPIWISDYVMMGYGTGAIMAVPAHDSRDWEFAKKFNIPIVEV  362
            TGV   G   INP+  KE+P+WI+DYV+ +YGTGAIMAVPAHD RDWEFAK+FN+ I+ V
Sbjct  303  TGV-WTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  363  VKGGDVQNEVYKTSPQDILVNSDKFDGLTVEEAIPAIIRHIEENKLGEAKTNYKMKNWAF  422
            + GG+V++  +  + +++ +NSD +DGL    AI+ ++  +E + +G+ +  Y++++W F
Sbjct  362  LEGGNVEEAAF--TEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLF  419

Query  423  NRQRYWGEPIPIIHCEHCGMVPVPEEQLPVTLPDVEEYRPTNTGESPLANIEDWVKVTCP  482
            +RQRYWGEPIPIIH E+    +VPE +LP+ LP   + RP+ TGESPLAN+ DW+ VT  
Sbjct  420  SRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRE  479

Query  483  VCGKPAKRETDTMPQWAGSSWYFLRYMDPHNNDALASQEALDYWGPVDWYNGGMEHVSRH  542
               K ++RET+TMPQWAGSSWY+LRY+DPHN + LA +E L  W PVD Y GG EH   H
Sbjct  480  DGVK-GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLH  538

Query  543  LIYSRFWHQFLHDIDAVSYPEPYKKRTAQGLILGP-------------------------  577
            L+Y+RFWH+ L D++ V+  EP++K   QG+ILG                          
Sbjct  539  LLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHV  598

Query  578  --------DGEKMSKSRGNVINPNEIIDNYGADTLRTYIMFIGDYERPAVWSDSSVKGCK  629
                       KMSKS  NV+NP++++++YGADTLR Y MF+G  + +  WS+ ++ G +
Sbjct  599  ETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSR  658

Query  630  RFLERVWKLQEMVTEQNEYDKKHISLMHKTIKKVSEDFENVKFNTAIAAMMTAVNQFYDD  689
            +FL+RV +L       +E       + + T+K V+E+ +++KFNTAIA +M  VN    +
Sbjct  659  KFLDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKE  718

Query  690  EFITRKELQDFITLLYPIAPHICCEIWE-LQQFEKDMDHTDWPTWDESKTIDTVVEIPIQ  748
            + +     ++F+ L+ P+APH+  E+W+ L      +    WP+ DESK ++  VEI +Q
Sbjct  719  DKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQ  778

Query  749  INGKIRGKVTVSKDITQEELLKIVETEENIKNFIGDKKVIKTIYVPGKILNMVIK  803
            I+GK+++K+ V+KD+++EEL  +  ++E+++  I++K +IK I VP K++N+VIK
Sbjct  779  IKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

675) leuS in NC_016640


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  617 bits (2330),  Expect = 1e-177, Method: Compositional matrix adjust.
 Identities = 387/860 (45%), Positives = 584/860 (68%), Gaps = 37/860 (4%)

Query  5    YNPASIEQKWQNTWAEQGLYQTHQDPNKPKFYALSMFPYPSGS-LHMGHVRNYTITDVIA  63
            Y+ ++IE KWQ  WA++  ++T  D++KPKFYAL MFPYPSG+ LH+GH   YT TD+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RLKRMQGYRVLHPMGWDAFGLPAENAAIDRGIPPQTWTYQNIAQMREQLQRLGFSIDWDA  123
            R+KR QG  VLHPMGWDAFGLPAE+ A+D G  P   T +NIA+ + Q++ LGFS DWD 
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVTTCSPEYYRWTQWIFLQFFQAGLAYQKESAVNWDPIDQTVLANEQVDNEGRSWRSGAI  183
            EV T  P+YY+WTQWIF ++++ GLAY+ E +VNW     T +ANE+V  +G S R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  184  VERKLLRQWFLKITDYAEELLNDLEKLPGWPERVKLMQANWIGKSVGARLDFPIVGVDDQ  243
            V RK +RQW LKIT YAE LL+DLE + +WPE +K MQ NWIGKS GA + F + + D +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  244  ISVFTTRPDTVYGVTYVVLAPEHPLVAQVTTPDRKAEVEGFIKQVTAESEMERTAEDKPK  303
            ++VFTTRPDT++G TY VLAPEH+LV  +TT+D+   V ++ +Q +  S++ RT   K K
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEK  302

Query  304  RGIPTGGKAINPFTKKEVPIWIADYVLYEYGTGAVMGVPAHDVRDFAFATQYNLPIRQVI  363
             G+ TG+ AINP   KE+P+WIADYVL  YGTGA+M+VPAHD RD  FA Q+NL I  V+
Sbjct  303  TGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL  362

Query  364  VpddadndndpddEVKQAYTEPGIMVNSGPFSGEHSSHGKQAVIEYAEDEGYGEGRVQYR  423
              ++ +           A+TE G+ +NS+ + G + + +   ++E  E EG G+  V YR
Sbjct  363  EGGNVE---------EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYR  413

Query  424  LRDWLISRQRYWGCPIPIIHCPDCGAVPVPDADLPVKLPENVEF--SGRGPSPLASLEDW  481
            LRDWL+SRQRYWG PIPIIH  D  + +VP+++LP+ LP   ++  SG G SPLA++ DW
Sbjct  414  LRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDW  473

Query  482  VNVPCPSCGTPAKRETDTMDTFIDSSWYFLRYPDAQNADQVFDLSKTNDWMPVDQYVGGI  541
            ++V     G  ++RET+TM    +SSWY+LRY D++N++++ D    ++W+PVD YVGG 
Sbjct  474  LEVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGA  532

Query  542  EHAILHLLYSRFFTKVLRDRNLLKFDEPFQRLLTQGMVQGITYKNPKTGKYIPPDKVNTN  601
            EHA+LHLLY+RF  KVL D  ++   EPFQ+L+ QGM+ G +Y++++ G  ++ DKV+  
Sbjct  533  EHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSR-GALVATDKVEKR  591

Query  602  EPK--DPETGDRLQVFFEKMSKSKYNGVDPLLVMEKYGADTARMFILFKAPPEKDLEWDD  659
            +    + ETG+ L+    KMSKS  N V+P  V+E+YGADT R++ +F +P +  + W +
Sbjct  592  DGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSE  651

Query  660  ADVEGQFRFLNRVWRLVTEFAANHSVSSTKSTPENLNKAEKDLRRAINNAIKEVTEDLEG  719
             ++EG  +FL+RV RL+T          TK   E+       L +  N+++K VTE+++ 
Sbjct  652  EGLEGSRKFLDRVYRLIT----------TKEITEE---NSGALDKVYNETVKAVTEQVD-  697

Query  720  DYQFNTAVSEMMKLSNALSDATPIQDSPIYQEGIDTLLKLLAPFSPHITEDLWHQI-GHG  778
            + +FNTA++++M + NA     + ++  ++ +    +++L+APF+PH+ E+LW+ + + G
Sbjct  698  QMKFNTAIAQLMVFVNA-----ANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASG  752

Query  779  DSVHLQSWPTFDPSALVVDEITLVIQINGKTRGTIQVASGADKSTLEQLAKDSEIAQRHL  838
            +S+   +WP++D S LV +++ +V+QI+GK ++ + VA +  +  L+++A  +E  Q ++
Sbjct  753  ESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEI  812

Query  839  EGKQLRKVIVVPGKLVNFVV  858
             GK++ KVI VP KLVN+V+
Sbjct  813  AGKDIIKVIAVPNKLVNIVI  832

676) leuS in NC_017502


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  617 bits (2333),  Expect = 6e-178, Method: Compositional matrix adjust.
 Identities = 388/854 (46%), Positives = 573/854 (68%), Gaps = 74/854 (8%)

Query  2    YNHNLIEKKWAKIWNDQKIYSFQIDKNKPKYYILDMFPYPSGKGLHVGHVKAYMATDVIS  61
            Y+H  IE KW  +W D+  +    D +KPK+Y LDMFPYPSG GLHVGH  +Y ATD++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  62   RWKNALGFNVLHPIGWDAFGLPAEQYAIQTNNHPAKFTQENINNFRTQLKRLGFNYDYRL  121
            R K A G NVLHP+GWDAFGLPAEQYA++T N+PA FT ENI NF+ Q++ LGF+YD   
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  122  EVDTTNKNYFKWTQWIFKKLYEHDLAYQADIEVNWCEQLGTVLANEEVLTDENGNKISER  181
            EV+TT+ NY+KWTQWIF KLYE +LAY+A++ VNW E+LGT +ANEEVL D      SER
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGT----SER  179

Query  182  GSYPVIKKKMRQWVLKITAFADQLIDDLENLNWPNSIKAMQVNWINKSVGASIKFEIDQL  241
            G+YPV++K MRQW+LKITA+A++L++DLE+++WP+SIK MQ NWI KS GA++ F + + 
Sbjct  180  GGYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDT  239

Query  242  DNQTIEVFSSRADTLFGASFLALSFDHPLVKQKLITDKNNAIEQFIKDNSIDQRV-RYQ-  299
            D++ + VF++R+DTLFGA++  L+ +H+LV     +D+ +A+ ++ ++ S+   + R + 
Sbjct  240  DKD-FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDL  298

Query  300  -----GINTNYFAIHPITKKKIPIYLADYILSDYGTGAVMGVPAHDERDYQFAKQYDLEI  354
                 G+ T  +AI+P+  K +P+ +ADY+L+ YGTGA+M+VPAHDERD +FAKQ++L+I
Sbjct  299  AKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDI  358

Query  355  IPVIKA---DQYPYLLDGEHINSEFNNGLNNEQAIQKTIAYLREHNLGDQKINYKLRDWI  411
            IPV+ +   ++ ++  DG HINS+F +GL++  AI K +  L  + +G++++ Y+LRDW+
Sbjct  359  IPVLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWL  418

Query  412  FSRQRYWGEPFPVLFDEEDNIYLLKDSELPVELPQLSDFSPNKDGLPPLANADDQWLHPI  471
            FSRQRYWGEP+P++  E++    + +SELP+ LP   D+ P+  G +PLAN  D WL+  
Sbjct  419  FSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTD-WLEVT  477

Query  472  IDQK-KYRREINTMPQWAGSCWYYLAYLLKLTDLNQADGDQNYLALNSEKAKELFDHFMP  530
             ++  K RRE NTMPQWAGS WYYL Y+          + +N   L  E   EL+ + +P
Sbjct  478  REDGVKGRRETNTMPQWAGSSWYYLRYI----------DPHNTEKLADE---ELLKQWLP  524

Query  531  VDLYVGGQEHAVLHLLYARFWYKFLHHIKIVSSTEPFSQLINQGMILG------------  578
            VD+YVGG EHAVLHLLYARFW K L ++ +V++ EPF +L+NQGMILG            
Sbjct  525  VDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVA  584

Query  579  ---------------------EDNTKMSKSKGNIINPDDLVLSHGADTIRTYVMFMGPln  617
                                 +  +KMSKS  N++NPDD+V   GADT+R Y MFMGPL+
Sbjct  585  TDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLD  644

Query  618  aslawnsnalnGTRKFLERVYNLFDRVEINDSINQNLNYDYHNFLKKINKHLENFEFNLV  677
            AS+AW+ ++L+G+RKFL+RVY L+   EI +  +  L+  Y++ +K +  ++++  FN  
Sbjct  645  ASIAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTA  704

Query  678  VSEMMIFINACYKQTQVNKEMITNFLIVLSFFAPYLAEELNSKLNNPTLLYKMRLAQW--  735
            ++++M+F+NA  K+ ++  +    F+ +++ FAP L+EEL   L  +     +    W  
Sbjct  705  IAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGE--SISYVPWPS  762

Query  736  -DEAYLVKNTTTISCSINGKF--KLVHEFDLDSDE-QEVANYFLNQDLIKRNLENKKLVK  791
             DE+ LV N   I   I+GK   KLV   DL  +E QEVA   L ++ ++ ++  K ++K
Sbjct  763  YDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVA---LANEKVQAEIAGKDIIK  819

Query  792  TIFVKNKVINFIIK  805
             I V NK++N++IK
Sbjct  820  VIAVPNKLVNIVIK  833

677) leuS in NC_004829


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  617 bits (2333),  Expect = 6e-178, Method: Compositional matrix adjust.
 Identities = 388/854 (46%), Positives = 573/854 (68%), Gaps = 74/854 (8%)

Query  2    YNHNLIEKKWAKIWNDQKIYSFQIDKNKPKYYILDMFPYPSGKGLHVGHVKAYMATDVIS  61
            Y+H  IE KW  +W D+  +    D +KPK+Y LDMFPYPSG GLHVGH  +Y ATD++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  62   RWKNALGFNVLHPIGWDAFGLPAEQYAIQTNNHPAKFTQENINNFRTQLKRLGFNYDYRL  121
            R K A G NVLHP+GWDAFGLPAEQYA++T N+PA FT ENI NF+ Q++ LGF+YD   
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  122  EVDTTNKNYFKWTQWIFKKLYEHDLAYQADIEVNWCEQLGTVLANEEVLTDENGNKISER  181
            EV+TT+ NY+KWTQWIF KLYE +LAY+A++ VNW E+LGT +ANEEVL D      SER
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGT----SER  179

Query  182  GSYPVIKKKMRQWVLKITAFADQLIDDLENLNWPNSIKAMQVNWINKSVGASIKFEIDQL  241
            G+YPV++K MRQW+LKITA+A++L++DLE+++WP+SIK MQ NWI KS GA++ F + + 
Sbjct  180  GGYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDT  239

Query  242  DNQTIEVFSSRADTLFGASFLALSFDHPLVKQKLITDKNNAIEQFIKDNSIDQRV-RYQ-  299
            D++ + VF++R+DTLFGA++  L+ +H+LV     +D+ +A+ ++ ++ S+   + R + 
Sbjct  240  DKD-FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDL  298

Query  300  -----GINTNYFAIHPITKKKIPIYLADYILSDYGTGAVMGVPAHDERDYQFAKQYDLEI  354
                 G+ T  +AI+P+  K +P+ +ADY+L+ YGTGA+M+VPAHDERD +FAKQ++L+I
Sbjct  299  AKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDI  358

Query  355  IPVIKA---DQYPYLLDGEHINSEFNNGLNNEQAIQKTIAYLREHNLGDQKINYKLRDWI  411
            IPV+ +   ++ ++  DG HINS+F +GL++  AI K +  L  + +G++++ Y+LRDW+
Sbjct  359  IPVLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWL  418

Query  412  FSRQRYWGEPFPVLFDEEDNIYLLKDSELPVELPQLSDFSPNKDGLPPLANADDQWLHPI  471
            FSRQRYWGEP+P++  E++    + +SELP+ LP   D+ P+  G +PLAN  D WL+  
Sbjct  419  FSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTD-WLEVT  477

Query  472  IDQK-KYRREINTMPQWAGSCWYYLAYLLKLTDLNQADGDQNYLALNSEKAKELFDHFMP  530
             ++  K RRE NTMPQWAGS WYYL Y+          + +N   L  E   EL+ + +P
Sbjct  478  REDGVKGRRETNTMPQWAGSSWYYLRYI----------DPHNTEKLADE---ELLKQWLP  524

Query  531  VDLYVGGQEHAVLHLLYARFWYKFLHHIKIVSSTEPFSQLINQGMILG------------  578
            VD+YVGG EHAVLHLLYARFW K L ++ +V++ EPF +L+NQGMILG            
Sbjct  525  VDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVA  584

Query  579  ---------------------EDNTKMSKSKGNIINPDDLVLSHGADTIRTYVMFMGPln  617
                                 +  +KMSKS  N++NPDD+V   GADT+R Y MFMGPL+
Sbjct  585  TDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLD  644

Query  618  aslawnsnalnGTRKFLERVYNLFDRVEINDSINQNLNYDYHNFLKKINKHLENFEFNLV  677
            AS+AW+ ++L+G+RKFL+RVY L+   EI +  +  L+  Y++ +K +  ++++  FN  
Sbjct  645  ASIAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTA  704

Query  678  VSEMMIFINACYKQTQVNKEMITNFLIVLSFFAPYLAEELNSKLNNPTLLYKMRLAQW--  735
            ++++M+F+NA  K+ ++  +    F+ +++ FAP L+EEL   L  +     +    W  
Sbjct  705  IAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGE--SISYVPWPS  762

Query  736  -DEAYLVKNTTTISCSINGKF--KLVHEFDLDSDE-QEVANYFLNQDLIKRNLENKKLVK  791
             DE+ LV N   I   I+GK   KLV   DL  +E QEVA   L ++ ++ ++  K ++K
Sbjct  763  YDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVA---LANEKVQAEIAGKDIIK  819

Query  792  TIFVKNKVINFIIK  805
             I V NK++N++IK
Sbjct  820  VIAVPNKLVNIVIK  833

678) leuS in NC_018412


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  617 bits (2332),  Expect = 8e-178, Method: Compositional matrix adjust.
 Identities = 391/854 (46%), Positives = 573/854 (68%), Gaps = 74/854 (8%)

Query  2    YNHNLIEKKWAKIWNDQKVYSFQIDKNKPKYYILDMFPYPSGKGLHVGHVKAYMATDVIS  61
            Y+H  IE KW  +W D+  +    D +KPK+Y LDMFPYPSG GLHVGH  +Y ATD++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  62   RWKNALGFNVLHPIGWDAFGLPAEQYAIQTNNHPAKFTQENINNFRTQLKRLGFNYDYRL  121
            R K A G NVLHP+GWDAFGLPAEQYA++T N+PA FT ENI NF+ Q++ LGF+YD   
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  122  EVDTTNKNYFKWTQWIFKKLYEHDLAYQADIEVNWCEQLGTVLANEEVLTDENGNKISER  181
            EV+TT+ NY+KWTQWIF KLYE +LAY+A++ VNW E+LGT +ANEEVL D      SER
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGT----SER  179

Query  182  GSYPVIKKKMRQWVLKITAFADQLIDDLENLNWPNSIKAMQVNWINKSIGASIKFEIDQL  241
            G+YPV++K MRQW+LKITA+A++L++DLE+++WP+SIK MQ NWI KS GA++ F + + 
Sbjct  180  GGYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDT  239

Query  242  DNQTIEVFSSRADTLFGASFLALSFDHPLVKQKLITDKNNAIEQFIKDNSIDQTV-RYQ-  299
            D++ + VF++R+DTLFGA++  L+ +H+LV     +D+ +A+ ++ ++ S+   + R + 
Sbjct  240  DKD-FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDL  298

Query  300  -----GINTNYFAIHPITKKKIPIYLADYILSDYGTGAVMGVPAHDERDYQFAKQYDLEI  354
                 G+ T  +AI+P+  K +P+ +ADY+L+ YGTGA+M+VPAHDERD +FAKQ++L+I
Sbjct  299  AKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDI  358

Query  355  IPVIKA---DQYPYLLDGKHINSDFNNGLNNEQAIEKTIAYLREHNLGDQKINYKLRDWI  411
            IPV+ +   ++ ++  DG HINSDF +GL++  AI K +  L  + +G++++ Y+LRDW+
Sbjct  359  IPVLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWL  418

Query  412  FSRQRYWGEPFPVLFDEKDNIYLLKDSELPLELPQLSDFSPNKDGLPPLANADDQWLHPI  471
            FSRQRYWGEP+P++  E +    + +SELPL LP   D+ P+  G +PLAN  D WL+  
Sbjct  419  FSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTD-WLEVT  477

Query  472  IDQK-KYRREINTMPQWAGSCWYYLAYLLKLTDLNQADGDQNYLALNSEKAKELFDHFMP  530
             ++  K RRE NTMPQWAGS WYYL Y+          + +N   L  E   EL+ + +P
Sbjct  478  REDGVKGRRETNTMPQWAGSSWYYLRYI----------DPHNTEKLADE---ELLKQWLP  524

Query  531  VDLYVGGQEHAVLHLLYARFWYKFLHLIKIVSSIEPFSQLINQGMILG------------  578
            VD+YVGG EHAVLHLLYARFW K L  + +V++ EPF +L+NQGMILG            
Sbjct  525  VDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVA  584

Query  579  ---------------------EDNTKMSKSKGNIINPDDLVLSHGADTIRTYVMFMGPln  617
                                 +  +KMSKS  N++NPDD+V   GADT+R Y MFMGPL+
Sbjct  585  TDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLD  644

Query  618  aslawnsnalnGTRKFLERVYNLFERVEINDSINPNLNYDYHNFLKKVNKHLENFEFNLV  677
            AS+AW+ ++L+G+RKFL+RVY L+   EI +  +  L+  Y++ +K V  ++++  FN  
Sbjct  645  ASIAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTA  704

Query  678  VSEMMIFINACYKQTQVNKEMITNFLIVLSFFAPYLAEELNNRLNNPTLLYKMKLAQW--  735
            ++++M+F+NA  K+ ++  +    F+ +++ FAP L+EEL + L  +     +    W  
Sbjct  705  IAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGE--SISYVPWPS  762

Query  736  -DEAYLVKNTTAISCSINGKF--KLVHEFDLDSDE-QEVANYFLNQDLIKRNLEDKKLVK  791
             DE+ LV N   I   I+GK   KLV   DL  +E QEVA   L ++ ++ ++ +K ++K
Sbjct  763  YDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVA---LANEKVQAEIAGKDIIK  819

Query  792  TIFVKNKVINFIIK  805
             I V NK++N++IK
Sbjct  820  VIAVPNKLVNIVIK  833

679) leuS in NC_018411


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  617 bits (2332),  Expect = 8e-178, Method: Compositional matrix adjust.
 Identities = 391/854 (46%), Positives = 573/854 (68%), Gaps = 74/854 (8%)

Query  2    YNHNLIEKKWAKIWNDQKVYSFQIDKNKPKYYILDMFPYPSGKGLHVGHVKAYMATDVIS  61
            Y+H  IE KW  +W D+  +    D +KPK+Y LDMFPYPSG GLHVGH  +Y ATD++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  62   RWKNALGFNVLHPIGWDAFGLPAEQYAIQTNNHPAKFTQENINNFRTQLKRLGFNYDYRL  121
            R K A G NVLHP+GWDAFGLPAEQYA++T N+PA FT ENI NF+ Q++ LGF+YD   
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  122  EVDTTNKNYFKWTQWIFKKLYEHDLAYQADIEVNWCEQLGTVLANEEVLTDENGNKISER  181
            EV+TT+ NY+KWTQWIF KLYE +LAY+A++ VNW E+LGT +ANEEVL D      SER
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGT----SER  179

Query  182  GSYPVIKKKMRQWVLKITAFADQLIDDLENLNWPNSIKAMQVNWINKSIGASIKFEIDQL  241
            G+YPV++K MRQW+LKITA+A++L++DLE+++WP+SIK MQ NWI KS GA++ F + + 
Sbjct  180  GGYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDT  239

Query  242  DNQTIEVFSSRADTLFGASFLALSFDHPLVKQKLITDKNNAIEQFIKDNSIDQTV-RYQ-  299
            D++ + VF++R+DTLFGA++  L+ +H+LV     +D+ +A+ ++ ++ S+   + R + 
Sbjct  240  DKD-FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDL  298

Query  300  -----GINTNYFAIHPITKKKIPIYLADYILSDYGTGAVMGVPAHDERDYQFAKQYDLEI  354
                 G+ T  +AI+P+  K +P+ +ADY+L+ YGTGA+M+VPAHDERD +FAKQ++L+I
Sbjct  299  AKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDI  358

Query  355  IPVIKA---DQYPYLLDGKHINSDFNNGLNNEQAIEKTIAYLREHNLGDQKINYKLRDWI  411
            IPV+ +   ++ ++  DG HINSDF +GL++  AI K +  L  + +G++++ Y+LRDW+
Sbjct  359  IPVLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWL  418

Query  412  FSRQRYWGEPFPVLFDEKDNIYLLKDSELPLELPQLSDFSPNKDGLPPLANADDQWLHPI  471
            FSRQRYWGEP+P++  E +    + +SELPL LP   D+ P+  G +PLAN  D WL+  
Sbjct  419  FSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTD-WLEVT  477

Query  472  IDQK-KYRREINTMPQWAGSCWYYLAYLLKLTDLNQADGDQNYLALNSEKAKELFDHFMP  530
             ++  K RRE NTMPQWAGS WYYL Y+          + +N   L  E   EL+ + +P
Sbjct  478  REDGVKGRRETNTMPQWAGSSWYYLRYI----------DPHNTEKLADE---ELLKQWLP  524

Query  531  VDLYVGGQEHAVLHLLYARFWYKFLHLIKIVSSIEPFSQLINQGMILG------------  578
            VD+YVGG EHAVLHLLYARFW K L  + +V++ EPF +L+NQGMILG            
Sbjct  525  VDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVA  584

Query  579  ---------------------EDNTKMSKSKGNIINPDDLVLSHGADTIRTYVMFMGPln  617
                                 +  +KMSKS  N++NPDD+V   GADT+R Y MFMGPL+
Sbjct  585  TDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLD  644

Query  618  aslawnsnalnGTRKFLERVYNLFERVEINDSINPNLNYDYHNFLKKVNKHLENFEFNLV  677
            AS+AW+ ++L+G+RKFL+RVY L+   EI +  +  L+  Y++ +K V  ++++  FN  
Sbjct  645  ASIAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTA  704

Query  678  VSEMMIFINACYKQTQVNKEMITNFLIVLSFFAPYLAEELNNRLNNPTLLYKMKLAQW--  735
            ++++M+F+NA  K+ ++  +    F+ +++ FAP L+EEL + L  +     +    W  
Sbjct  705  IAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGE--SISYVPWPS  762

Query  736  -DEAYLVKNTTAISCSINGKF--KLVHEFDLDSDE-QEVANYFLNQDLIKRNLEDKKLVK  791
             DE+ LV N   I   I+GK   KLV   DL  +E QEVA   L ++ ++ ++ +K ++K
Sbjct  763  YDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVA---LANEKVQAEIAGKDIIK  819

Query  792  TIFVKNKVINFIIK  805
             I V NK++N++IK
Sbjct  820  VIAVPNKLVNIVIK  833

680) leuS in NC_018413


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  617 bits (2332),  Expect = 8e-178, Method: Compositional matrix adjust.
 Identities = 391/854 (46%), Positives = 573/854 (68%), Gaps = 74/854 (8%)

Query  2    YNHNLIEKKWAKIWNDQKVYSFQIDKNKPKYYILDMFPYPSGKGLHVGHVKAYMATDVIS  61
            Y+H  IE KW  +W D+  +    D +KPK+Y LDMFPYPSG GLHVGH  +Y ATD++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  62   RWKNALGFNVLHPIGWDAFGLPAEQYAIQTNNHPAKFTQENINNFRTQLKRLGFNYDYRL  121
            R K A G NVLHP+GWDAFGLPAEQYA++T N+PA FT ENI NF+ Q++ LGF+YD   
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  122  EVDTTNKNYFKWTQWIFKKLYEHDLAYQADIEVNWCEQLGTVLANEEVLTDENGNKISER  181
            EV+TT+ NY+KWTQWIF KLYE +LAY+A++ VNW E+LGT +ANEEVL D      SER
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGT----SER  179

Query  182  GSYPVIKKKMRQWVLKITAFADQLIDDLENLNWPNSIKAMQVNWINKSIGASIKFEIDQL  241
            G+YPV++K MRQW+LKITA+A++L++DLE+++WP+SIK MQ NWI KS GA++ F + + 
Sbjct  180  GGYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDT  239

Query  242  DNQTIEVFSSRADTLFGASFLALSFDHPLVKQKLITDKNNAIEQFIKDNSIDQTV-RYQ-  299
            D++ + VF++R+DTLFGA++  L+ +H+LV     +D+ +A+ ++ ++ S+   + R + 
Sbjct  240  DKD-FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDL  298

Query  300  -----GINTNYFAIHPITKKKIPIYLADYILSDYGTGAVMGVPAHDERDYQFAKQYDLEI  354
                 G+ T  +AI+P+  K +P+ +ADY+L+ YGTGA+M+VPAHDERD +FAKQ++L+I
Sbjct  299  AKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDI  358

Query  355  IPVIKA---DQYPYLLDGKHINSDFNNGLNNEQAIEKTIAYLREHNLGDQKINYKLRDWI  411
            IPV+ +   ++ ++  DG HINSDF +GL++  AI K +  L  + +G++++ Y+LRDW+
Sbjct  359  IPVLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWL  418

Query  412  FSRQRYWGEPFPVLFDEKDNIYLLKDSELPLELPQLSDFSPNKDGLPPLANADDQWLHPI  471
            FSRQRYWGEP+P++  E +    + +SELPL LP   D+ P+  G +PLAN  D WL+  
Sbjct  419  FSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTD-WLEVT  477

Query  472  IDQK-KYRREINTMPQWAGSCWYYLAYLLKLTDLNQADGDQNYLALNSEKAKELFDHFMP  530
             ++  K RRE NTMPQWAGS WYYL Y+          + +N   L  E   EL+ + +P
Sbjct  478  REDGVKGRRETNTMPQWAGSSWYYLRYI----------DPHNTEKLADE---ELLKQWLP  524

Query  531  VDLYVGGQEHAVLHLLYARFWYKFLHLIKIVSSIEPFSQLINQGMILG------------  578
            VD+YVGG EHAVLHLLYARFW K L  + +V++ EPF +L+NQGMILG            
Sbjct  525  VDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVA  584

Query  579  ---------------------EDNTKMSKSKGNIINPDDLVLSHGADTIRTYVMFMGPln  617
                                 +  +KMSKS  N++NPDD+V   GADT+R Y MFMGPL+
Sbjct  585  TDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLD  644

Query  618  aslawnsnalnGTRKFLERVYNLFERVEINDSINPNLNYDYHNFLKKVNKHLENFEFNLV  677
            AS+AW+ ++L+G+RKFL+RVY L+   EI +  +  L+  Y++ +K V  ++++  FN  
Sbjct  645  ASIAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTA  704

Query  678  VSEMMIFINACYKQTQVNKEMITNFLIVLSFFAPYLAEELNNRLNNPTLLYKMKLAQW--  735
            ++++M+F+NA  K+ ++  +    F+ +++ FAP L+EEL + L  +     +    W  
Sbjct  705  IAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGE--SISYVPWPS  762

Query  736  -DEAYLVKNTTAISCSINGKF--KLVHEFDLDSDE-QEVANYFLNQDLIKRNLEDKKLVK  791
             DE+ LV N   I   I+GK   KLV   DL  +E QEVA   L ++ ++ ++ +K ++K
Sbjct  763  YDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVA---LANEKVQAEIAGKDIIK  819

Query  792  TIFVKNKVINFIIK  805
             I V NK++N++IK
Sbjct  820  VIAVPNKLVNIVIK  833

681) leuS in NC_018407


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  617 bits (2332),  Expect = 8e-178, Method: Compositional matrix adjust.
 Identities = 391/854 (46%), Positives = 573/854 (68%), Gaps = 74/854 (8%)

Query  2    YNHNLIEKKWAKIWNDQKVYSFQIDKNKPKYYILDMFPYPSGKGLHVGHVKAYMATDVIS  61
            Y+H  IE KW  +W D+  +    D +KPK+Y LDMFPYPSG GLHVGH  +Y ATD++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  62   RWKNALGFNVLHPIGWDAFGLPAEQYAIQTNNHPAKFTQENINNFRTQLKRLGFNYDYRL  121
            R K A G NVLHP+GWDAFGLPAEQYA++T N+PA FT ENI NF+ Q++ LGF+YD   
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  122  EVDTTNKNYFKWTQWIFKKLYEHDLAYQADIEVNWCEQLGTVLANEEVLTDENGNKISER  181
            EV+TT+ NY+KWTQWIF KLYE +LAY+A++ VNW E+LGT +ANEEVL D      SER
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGT----SER  179

Query  182  GSYPVIKKKMRQWVLKITAFADQLIDDLENLNWPNSIKAMQVNWINKSIGASIKFEIDQL  241
            G+YPV++K MRQW+LKITA+A++L++DLE+++WP+SIK MQ NWI KS GA++ F + + 
Sbjct  180  GGYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDT  239

Query  242  DNQTIEVFSSRADTLFGASFLALSFDHPLVKQKLITDKNNAIEQFIKDNSIDQTV-RYQ-  299
            D++ + VF++R+DTLFGA++  L+ +H+LV     +D+ +A+ ++ ++ S+   + R + 
Sbjct  240  DKD-FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDL  298

Query  300  -----GINTNYFAIHPITKKKIPIYLADYILSDYGTGAVMGVPAHDERDYQFAKQYDLEI  354
                 G+ T  +AI+P+  K +P+ +ADY+L+ YGTGA+M+VPAHDERD +FAKQ++L+I
Sbjct  299  AKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDI  358

Query  355  IPVIKA---DQYPYLLDGKHINSDFNNGLNNEQAIEKTIAYLREHNLGDQKINYKLRDWI  411
            IPV+ +   ++ ++  DG HINSDF +GL++  AI K +  L  + +G++++ Y+LRDW+
Sbjct  359  IPVLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWL  418

Query  412  FSRQRYWGEPFPVLFDEKDNIYLLKDSELPLELPQLSDFSPNKDGLPPLANADDQWLHPI  471
            FSRQRYWGEP+P++  E +    + +SELPL LP   D+ P+  G +PLAN  D WL+  
Sbjct  419  FSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTD-WLEVT  477

Query  472  IDQK-KYRREINTMPQWAGSCWYYLAYLLKLTDLNQADGDQNYLALNSEKAKELFDHFMP  530
             ++  K RRE NTMPQWAGS WYYL Y+          + +N   L  E   EL+ + +P
Sbjct  478  REDGVKGRRETNTMPQWAGSSWYYLRYI----------DPHNTEKLADE---ELLKQWLP  524

Query  531  VDLYVGGQEHAVLHLLYARFWYKFLHLIKIVSSIEPFSQLINQGMILG------------  578
            VD+YVGG EHAVLHLLYARFW K L  + +V++ EPF +L+NQGMILG            
Sbjct  525  VDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVA  584

Query  579  ---------------------EDNTKMSKSKGNIINPDDLVLSHGADTIRTYVMFMGPln  617
                                 +  +KMSKS  N++NPDD+V   GADT+R Y MFMGPL+
Sbjct  585  TDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLD  644

Query  618  aslawnsnalnGTRKFLERVYNLFERVEINDSINPNLNYDYHNFLKKVNKHLENFEFNLV  677
            AS+AW+ ++L+G+RKFL+RVY L+   EI +  +  L+  Y++ +K V  ++++  FN  
Sbjct  645  ASIAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTA  704

Query  678  VSEMMIFINACYKQTQVNKEMITNFLIVLSFFAPYLAEELNNRLNNPTLLYKMKLAQW--  735
            ++++M+F+NA  K+ ++  +    F+ +++ FAP L+EEL + L  +     +    W  
Sbjct  705  IAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGE--SISYVPWPS  762

Query  736  -DEAYLVKNTTAISCSINGKF--KLVHEFDLDSDE-QEVANYFLNQDLIKRNLEDKKLVK  791
             DE+ LV N   I   I+GK   KLV   DL  +E QEVA   L ++ ++ ++ +K ++K
Sbjct  763  YDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVA---LANEKVQAEIAGKDIIK  819

Query  792  TIFVKNKVINFIIK  805
             I V NK++N++IK
Sbjct  820  VIAVPNKLVNIVIK  833

682) leuS in NC_018408


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  617 bits (2332),  Expect = 8e-178, Method: Compositional matrix adjust.
 Identities = 391/854 (46%), Positives = 573/854 (68%), Gaps = 74/854 (8%)

Query  2    YNHNLIEKKWAKIWNDQKVYSFQIDKNKPKYYILDMFPYPSGKGLHVGHVKAYMATDVIS  61
            Y+H  IE KW  +W D+  +    D +KPK+Y LDMFPYPSG GLHVGH  +Y ATD++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  62   RWKNALGFNVLHPIGWDAFGLPAEQYAIQTNNHPAKFTQENINNFRTQLKRLGFNYDYRL  121
            R K A G NVLHP+GWDAFGLPAEQYA++T N+PA FT ENI NF+ Q++ LGF+YD   
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  122  EVDTTNKNYFKWTQWIFKKLYEHDLAYQADIEVNWCEQLGTVLANEEVLTDENGNKISER  181
            EV+TT+ NY+KWTQWIF KLYE +LAY+A++ VNW E+LGT +ANEEVL D      SER
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGT----SER  179

Query  182  GSYPVIKKKMRQWVLKITAFADQLIDDLENLNWPNSIKAMQVNWINKSIGASIKFEIDQL  241
            G+YPV++K MRQW+LKITA+A++L++DLE+++WP+SIK MQ NWI KS GA++ F + + 
Sbjct  180  GGYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDT  239

Query  242  DNQTIEVFSSRADTLFGASFLALSFDHPLVKQKLITDKNNAIEQFIKDNSIDQTV-RYQ-  299
            D++ + VF++R+DTLFGA++  L+ +H+LV     +D+ +A+ ++ ++ S+   + R + 
Sbjct  240  DKD-FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDL  298

Query  300  -----GINTNYFAIHPITKKKIPIYLADYILSDYGTGAVMGVPAHDERDYQFAKQYDLEI  354
                 G+ T  +AI+P+  K +P+ +ADY+L+ YGTGA+M+VPAHDERD +FAKQ++L+I
Sbjct  299  AKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDI  358

Query  355  IPVIKA---DQYPYLLDGKHINSDFNNGLNNEQAIEKTIAYLREHNLGDQKINYKLRDWI  411
            IPV+ +   ++ ++  DG HINSDF +GL++  AI K +  L  + +G++++ Y+LRDW+
Sbjct  359  IPVLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWL  418

Query  412  FSRQRYWGEPFPVLFDEKDNIYLLKDSELPLELPQLSDFSPNKDGLPPLANADDQWLHPI  471
            FSRQRYWGEP+P++  E +    + +SELPL LP   D+ P+  G +PLAN  D WL+  
Sbjct  419  FSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTD-WLEVT  477

Query  472  IDQK-KYRREINTMPQWAGSCWYYLAYLLKLTDLNQADGDQNYLALNSEKAKELFDHFMP  530
             ++  K RRE NTMPQWAGS WYYL Y+          + +N   L  E   EL+ + +P
Sbjct  478  REDGVKGRRETNTMPQWAGSSWYYLRYI----------DPHNTEKLADE---ELLKQWLP  524

Query  531  VDLYVGGQEHAVLHLLYARFWYKFLHLIKIVSSIEPFSQLINQGMILG------------  578
            VD+YVGG EHAVLHLLYARFW K L  + +V++ EPF +L+NQGMILG            
Sbjct  525  VDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVA  584

Query  579  ---------------------EDNTKMSKSKGNIINPDDLVLSHGADTIRTYVMFMGPln  617
                                 +  +KMSKS  N++NPDD+V   GADT+R Y MFMGPL+
Sbjct  585  TDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLD  644

Query  618  aslawnsnalnGTRKFLERVYNLFERVEINDSINPNLNYDYHNFLKKVNKHLENFEFNLV  677
            AS+AW+ ++L+G+RKFL+RVY L+   EI +  +  L+  Y++ +K V  ++++  FN  
Sbjct  645  ASIAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTA  704

Query  678  VSEMMIFINACYKQTQVNKEMITNFLIVLSFFAPYLAEELNNRLNNPTLLYKMKLAQW--  735
            ++++M+F+NA  K+ ++  +    F+ +++ FAP L+EEL + L  +     +    W  
Sbjct  705  IAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGE--SISYVPWPS  762

Query  736  -DEAYLVKNTTAISCSINGKF--KLVHEFDLDSDE-QEVANYFLNQDLIKRNLEDKKLVK  791
             DE+ LV N   I   I+GK   KLV   DL  +E QEVA   L ++ ++ ++ +K ++K
Sbjct  763  YDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVA---LANEKVQAEIAGKDIIK  819

Query  792  TIFVKNKVINFIIK  805
             I V NK++N++IK
Sbjct  820  VIAVPNKLVNIVIK  833

683) leuS in NC_018409


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  617 bits (2332),  Expect = 8e-178, Method: Compositional matrix adjust.
 Identities = 391/854 (46%), Positives = 573/854 (68%), Gaps = 74/854 (8%)

Query  2    YNHNLIEKKWAKIWNDQKVYSFQIDKNKPKYYILDMFPYPSGKGLHVGHVKAYMATDVIS  61
            Y+H  IE KW  +W D+  +    D +KPK+Y LDMFPYPSG GLHVGH  +Y ATD++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  62   RWKNALGFNVLHPIGWDAFGLPAEQYAIQTNNHPAKFTQENINNFRTQLKRLGFNYDYRL  121
            R K A G NVLHP+GWDAFGLPAEQYA++T N+PA FT ENI NF+ Q++ LGF+YD   
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  122  EVDTTNKNYFKWTQWIFKKLYEHDLAYQADIEVNWCEQLGTVLANEEVLTDENGNKISER  181
            EV+TT+ NY+KWTQWIF KLYE +LAY+A++ VNW E+LGT +ANEEVL D      SER
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGT----SER  179

Query  182  GSYPVIKKKMRQWVLKITAFADQLIDDLENLNWPNSIKAMQVNWINKSIGASIKFEIDQL  241
            G+YPV++K MRQW+LKITA+A++L++DLE+++WP+SIK MQ NWI KS GA++ F + + 
Sbjct  180  GGYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDT  239

Query  242  DNQTIEVFSSRADTLFGASFLALSFDHPLVKQKLITDKNNAIEQFIKDNSIDQTV-RYQ-  299
            D++ + VF++R+DTLFGA++  L+ +H+LV     +D+ +A+ ++ ++ S+   + R + 
Sbjct  240  DKD-FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDL  298

Query  300  -----GINTNYFAIHPITKKKIPIYLADYILSDYGTGAVMGVPAHDERDYQFAKQYDLEI  354
                 G+ T  +AI+P+  K +P+ +ADY+L+ YGTGA+M+VPAHDERD +FAKQ++L+I
Sbjct  299  AKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDI  358

Query  355  IPVIKA---DQYPYLLDGKHINSDFNNGLNNEQAIEKTIAYLREHNLGDQKINYKLRDWI  411
            IPV+ +   ++ ++  DG HINSDF +GL++  AI K +  L  + +G++++ Y+LRDW+
Sbjct  359  IPVLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWL  418

Query  412  FSRQRYWGEPFPVLFDEKDNIYLLKDSELPLELPQLSDFSPNKDGLPPLANADDQWLHPI  471
            FSRQRYWGEP+P++  E +    + +SELPL LP   D+ P+  G +PLAN  D WL+  
Sbjct  419  FSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTD-WLEVT  477

Query  472  IDQK-KYRREINTMPQWAGSCWYYLAYLLKLTDLNQADGDQNYLALNSEKAKELFDHFMP  530
             ++  K RRE NTMPQWAGS WYYL Y+          + +N   L  E   EL+ + +P
Sbjct  478  REDGVKGRRETNTMPQWAGSSWYYLRYI----------DPHNTEKLADE---ELLKQWLP  524

Query  531  VDLYVGGQEHAVLHLLYARFWYKFLHLIKIVSSIEPFSQLINQGMILG------------  578
            VD+YVGG EHAVLHLLYARFW K L  + +V++ EPF +L+NQGMILG            
Sbjct  525  VDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVA  584

Query  579  ---------------------EDNTKMSKSKGNIINPDDLVLSHGADTIRTYVMFMGPln  617
                                 +  +KMSKS  N++NPDD+V   GADT+R Y MFMGPL+
Sbjct  585  TDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLD  644

Query  618  aslawnsnalnGTRKFLERVYNLFERVEINDSINPNLNYDYHNFLKKVNKHLENFEFNLV  677
            AS+AW+ ++L+G+RKFL+RVY L+   EI +  +  L+  Y++ +K V  ++++  FN  
Sbjct  645  ASIAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTA  704

Query  678  VSEMMIFINACYKQTQVNKEMITNFLIVLSFFAPYLAEELNNRLNNPTLLYKMKLAQW--  735
            ++++M+F+NA  K+ ++  +    F+ +++ FAP L+EEL + L  +     +    W  
Sbjct  705  IAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGE--SISYVPWPS  762

Query  736  -DEAYLVKNTTAISCSINGKF--KLVHEFDLDSDE-QEVANYFLNQDLIKRNLEDKKLVK  791
             DE+ LV N   I   I+GK   KLV   DL  +E QEVA   L ++ ++ ++ +K ++K
Sbjct  763  YDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVA---LANEKVQAEIAGKDIIK  819

Query  792  TIFVKNKVINFIIK  805
             I V NK++N++IK
Sbjct  820  VIAVPNKLVNIVIK  833

684) leuS in NC_018406


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  617 bits (2332),  Expect = 8e-178, Method: Compositional matrix adjust.
 Identities = 391/854 (46%), Positives = 573/854 (68%), Gaps = 74/854 (8%)

Query  2    YNHNLIEKKWAKIWNDQKVYSFQIDKNKPKYYILDMFPYPSGKGLHVGHVKAYMATDVIS  61
            Y+H  IE KW  +W D+  +    D +KPK+Y LDMFPYPSG GLHVGH  +Y ATD++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  62   RWKNALGFNVLHPIGWDAFGLPAEQYAIQTNNHPAKFTQENINNFRTQLKRLGFNYDYRL  121
            R K A G NVLHP+GWDAFGLPAEQYA++T N+PA FT ENI NF+ Q++ LGF+YD   
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  122  EVDTTNKNYFKWTQWIFKKLYEHDLAYQADIEVNWCEQLGTVLANEEVLTDENGNKISER  181
            EV+TT+ NY+KWTQWIF KLYE +LAY+A++ VNW E+LGT +ANEEVL D      SER
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGT----SER  179

Query  182  GSYPVIKKKMRQWVLKITAFADQLIDDLENLNWPNSIKAMQVNWINKSIGASIKFEIDQL  241
            G+YPV++K MRQW+LKITA+A++L++DLE+++WP+SIK MQ NWI KS GA++ F + + 
Sbjct  180  GGYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDT  239

Query  242  DNQTIEVFSSRADTLFGASFLALSFDHPLVKQKLITDKNNAIEQFIKDNSIDQTV-RYQ-  299
            D++ + VF++R+DTLFGA++  L+ +H+LV     +D+ +A+ ++ ++ S+   + R + 
Sbjct  240  DKD-FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDL  298

Query  300  -----GINTNYFAIHPITKKKIPIYLADYILSDYGTGAVMGVPAHDERDYQFAKQYDLEI  354
                 G+ T  +AI+P+  K +P+ +ADY+L+ YGTGA+M+VPAHDERD +FAKQ++L+I
Sbjct  299  AKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDI  358

Query  355  IPVIKA---DQYPYLLDGKHINSDFNNGLNNEQAIEKTIAYLREHNLGDQKINYKLRDWI  411
            IPV+ +   ++ ++  DG HINSDF +GL++  AI K +  L  + +G++++ Y+LRDW+
Sbjct  359  IPVLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWL  418

Query  412  FSRQRYWGEPFPVLFDEKDNIYLLKDSELPLELPQLSDFSPNKDGLPPLANADDQWLHPI  471
            FSRQRYWGEP+P++  E +    + +SELPL LP   D+ P+  G +PLAN  D WL+  
Sbjct  419  FSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTD-WLEVT  477

Query  472  IDQK-KYRREINTMPQWAGSCWYYLAYLLKLTDLNQADGDQNYLALNSEKAKELFDHFMP  530
             ++  K RRE NTMPQWAGS WYYL Y+          + +N   L  E   EL+ + +P
Sbjct  478  REDGVKGRRETNTMPQWAGSSWYYLRYI----------DPHNTEKLADE---ELLKQWLP  524

Query  531  VDLYVGGQEHAVLHLLYARFWYKFLHLIKIVSSIEPFSQLINQGMILG------------  578
            VD+YVGG EHAVLHLLYARFW K L  + +V++ EPF +L+NQGMILG            
Sbjct  525  VDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVA  584

Query  579  ---------------------EDNTKMSKSKGNIINPDDLVLSHGADTIRTYVMFMGPln  617
                                 +  +KMSKS  N++NPDD+V   GADT+R Y MFMGPL+
Sbjct  585  TDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLD  644

Query  618  aslawnsnalnGTRKFLERVYNLFERVEINDSINPNLNYDYHNFLKKVNKHLENFEFNLV  677
            AS+AW+ ++L+G+RKFL+RVY L+   EI +  +  L+  Y++ +K V  ++++  FN  
Sbjct  645  ASIAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTA  704

Query  678  VSEMMIFINACYKQTQVNKEMITNFLIVLSFFAPYLAEELNNRLNNPTLLYKMKLAQW--  735
            ++++M+F+NA  K+ ++  +    F+ +++ FAP L+EEL + L  +     +    W  
Sbjct  705  IAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGE--SISYVPWPS  762

Query  736  -DEAYLVKNTTAISCSINGKF--KLVHEFDLDSDE-QEVANYFLNQDLIKRNLEDKKLVK  791
             DE+ LV N   I   I+GK   KLV   DL  +E QEVA   L ++ ++ ++ +K ++K
Sbjct  763  YDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVA---LANEKVQAEIAGKDIIK  819

Query  792  TIFVKNKVINFIIK  805
             I V NK++N++IK
Sbjct  820  VIAVPNKLVNIVIK  833

685) leuS in NC_018410


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  617 bits (2332),  Expect = 8e-178, Method: Compositional matrix adjust.
 Identities = 391/854 (46%), Positives = 573/854 (68%), Gaps = 74/854 (8%)

Query  2    YNHNLIEKKWAKIWNDQKVYSFQIDKNKPKYYILDMFPYPSGKGLHVGHVKAYMATDVIS  61
            Y+H  IE KW  +W D+  +    D +KPK+Y LDMFPYPSG GLHVGH  +Y ATD++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  62   RWKNALGFNVLHPIGWDAFGLPAEQYAIQTNNHPAKFTQENINNFRTQLKRLGFNYDYRL  121
            R K A G NVLHP+GWDAFGLPAEQYA++T N+PA FT ENI NF+ Q++ LGF+YD   
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  122  EVDTTNKNYFKWTQWIFKKLYEHDLAYQADIEVNWCEQLGTVLANEEVLTDENGNKISER  181
            EV+TT+ NY+KWTQWIF KLYE +LAY+A++ VNW E+LGT +ANEEVL D      SER
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGT----SER  179

Query  182  GSYPVIKKKMRQWVLKITAFADQLIDDLENLNWPNSIKAMQVNWINKSIGASIKFEIDQL  241
            G+YPV++K MRQW+LKITA+A++L++DLE+++WP+SIK MQ NWI KS GA++ F + + 
Sbjct  180  GGYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDT  239

Query  242  DNQTIEVFSSRADTLFGASFLALSFDHPLVKQKLITDKNNAIEQFIKDNSIDQTV-RYQ-  299
            D++ + VF++R+DTLFGA++  L+ +H+LV     +D+ +A+ ++ ++ S+   + R + 
Sbjct  240  DKD-FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDL  298

Query  300  -----GINTNYFAIHPITKKKIPIYLADYILSDYGTGAVMGVPAHDERDYQFAKQYDLEI  354
                 G+ T  +AI+P+  K +P+ +ADY+L+ YGTGA+M+VPAHDERD +FAKQ++L+I
Sbjct  299  AKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDI  358

Query  355  IPVIKA---DQYPYLLDGKHINSDFNNGLNNEQAIEKTIAYLREHNLGDQKINYKLRDWI  411
            IPV+ +   ++ ++  DG HINSDF +GL++  AI K +  L  + +G++++ Y+LRDW+
Sbjct  359  IPVLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWL  418

Query  412  FSRQRYWGEPFPVLFDEKDNIYLLKDSELPLELPQLSDFSPNKDGLPPLANADDQWLHPI  471
            FSRQRYWGEP+P++  E +    + +SELPL LP   D+ P+  G +PLAN  D WL+  
Sbjct  419  FSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTD-WLEVT  477

Query  472  IDQK-KYRREINTMPQWAGSCWYYLAYLLKLTDLNQADGDQNYLALNSEKAKELFDHFMP  530
             ++  K RRE NTMPQWAGS WYYL Y+          + +N   L  E   EL+ + +P
Sbjct  478  REDGVKGRRETNTMPQWAGSSWYYLRYI----------DPHNTEKLADE---ELLKQWLP  524

Query  531  VDLYVGGQEHAVLHLLYARFWYKFLHLIKIVSSIEPFSQLINQGMILG------------  578
            VD+YVGG EHAVLHLLYARFW K L  + +V++ EPF +L+NQGMILG            
Sbjct  525  VDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVA  584

Query  579  ---------------------EDNTKMSKSKGNIINPDDLVLSHGADTIRTYVMFMGPln  617
                                 +  +KMSKS  N++NPDD+V   GADT+R Y MFMGPL+
Sbjct  585  TDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLD  644

Query  618  aslawnsnalnGTRKFLERVYNLFERVEINDSINPNLNYDYHNFLKKVNKHLENFEFNLV  677
            AS+AW+ ++L+G+RKFL+RVY L+   EI +  +  L+  Y++ +K V  ++++  FN  
Sbjct  645  ASIAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTA  704

Query  678  VSEMMIFINACYKQTQVNKEMITNFLIVLSFFAPYLAEELNNRLNNPTLLYKMKLAQW--  735
            ++++M+F+NA  K+ ++  +    F+ +++ FAP L+EEL + L  +     +    W  
Sbjct  705  IAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGE--SISYVPWPS  762

Query  736  -DEAYLVKNTTAISCSINGKF--KLVHEFDLDSDE-QEVANYFLNQDLIKRNLEDKKLVK  791
             DE+ LV N   I   I+GK   KLV   DL  +E QEVA   L ++ ++ ++ +K ++K
Sbjct  763  YDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVA---LANEKVQAEIAGKDIIK  819

Query  792  TIFVKNKVINFIIK  805
             I V NK++N++IK
Sbjct  820  VIAVPNKLVNIVIK  833

686) Tter_1009 in NC_013525


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  616 bits (2328),  Expect = 2e-177, Method: Compositional matrix adjust.
 Identities = 386/833 (47%), Positives = 551/833 (67%), Gaps = 44/833 (5%)

Query  19   AIEAKWRQRWQQTQIYKTDLRDESKPKYYNLMEFPYPSGEGLHVGHVYTYSGADTNGRYR  78
            AIE+KW+  W + + +KT+  D SKPK+Y L  FPYPSG GLHVGH   Y+++D  +R++
Sbjct  8    AIEPKWQAFWADNHTFKTG-TDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSRFK  66

Query  79   RMRGYNVFEPMGFDAFGIHSENYALKLGINPMVLTQRTVSRFREQMNRLGCMWDWSHEVN  138
            R +G NV++PMG DAFG+ +E+YA+  G +P  +T   ++ F+ Q+N LG   DW +EVN
Sbjct  67   RAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDREVN  126

Query  139  TSQPNYYKWTQWLFLQMYKAGLAVRKSAPVNWCPQCLTVLANEQVI-NGRCERCDTEVIQ  197
            T++PNYYKWTQW+F ++Y  GLA     PVNW  +  T +ANE+V+ +G  ER +  V++
Sbjct  127  TTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVR  186

Query  198  REMVQWFFKITDYAERLLNDLDKLDWPEVSKRLQRNWIGRSEGAELIFTIESTGDKVPVF  257
            + M QW +KIT YAERLL+DL+ +DWPE  K +QRNWIG+S GA++ F +  T+    VF
Sbjct  187  KPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVF  246

Query  258  TTRPDTVFGATYVVLAPEHPLVDKITTPECREAVQAYKEATMREREIERLSLEKEKTGVF  317
            TTRPDT+FGATY VLAPEH+LVD ITT++  EAV  YK  +    ++ R  L KEKTGV 
Sbjct  247  TTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVW  306

Query  318  TGAYAINPANGERIPVWIADYVLMTYGTGAIMAVPAHDERDHEFAKKFGLPIVEVVQSPE  377
            TG+YAINP NG  +PVWIADYVL +YGTGAIMAVPAHDERD EFAK+F L I+ V+++ +
Sbjct  307  TGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGN  366

Query  378  GVEEQAYIGPGQMKNSGQFDGMPNEEAKKAITDWLAERGLGKHTVTYRLRDWLISRQRYW  437
             VEE A+   G   NS+ +DG+ +  A   + +WL   G+G++ VTYRLRDWL+SRQRYW
Sbjct  367  -VEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYW  425

Query  438  GPPIPIIYCDNCGEVPVPEDQLPVELPYIENFRPTGTGKSPLALVEEFYKTECPNCGGPA  497
            G PIPII  ++    +VPE +LP+ LP   ++RP+GTG SPLA V +       + G  +
Sbjct  426  GEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED-GVKG  484

Query  498  VRETDVSDTFLDSSWYYLRYPSTEFDDRPFDRDITRKWLPVDSYMGGKEHIVLHHLYSRF  557
             RET+      +SSWYYLRY   +  ++  D ++ ++WLPVD Y+GG EH VLH LY+RF
Sbjct  485  RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARF  544

Query  558  VTKVLYDLGYLEFDEPFTRLRLHGII----------------------------------  583
              KVLYDLG +   EPF +L  +G+I                                  
Sbjct  545  WHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEEL  604

Query  584  THLGAKMSKSRGNVVNPDEYIEKYGADALRTYLLFMGPYEDDNEFSVHGVQGVSRFLNRL  643
             +  AKMSKS  NVVNPD+ +E+YGAD+LR Y +FMGP +     S +G++G  +FL+R+
Sbjct  605  EQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRV  664

Query  644  YSLVDSRHDYGNGPGVDMKMLHRTIDRVTRGIEDLKYHTSIAALMEMSNWIADVRSEMTK  703
            Y L+ +++   + +G   K+ + T+  VT  ++++K++T+IA LM   N      ++   
Sbjct  665  YRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVN-----AANKED  719

Query  704  EQLDTALKNLVLMLAPIAPHTAEELWERL-GGAYSVHIQPWPEYDPSQLVEETVTIVVQV  762
              +    K +V ++AP+APH +EELW+ L +++ S+   PWP YD S+LVE+ V IVVQ+
Sbjct  720  KLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQI  779

Query  763  NGKVRDKLELPYNVAQEEAQRAALESEKVRAHLDGKSVKNVIWVPGKLINIVV  815
            +GKV+ KL ++ ++++EE Q  AL +EKV+A++ GK + +VI VP KL+NIV+
Sbjct  780  KGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

687) leuS in NC_009012


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  615 bits (2324),  Expect = 4e-177, Method: Compositional matrix adjust.
 Identities = 388/844 (46%), Positives = 560/844 (67%), Gaps = 71/844 (8%)

Query  21   AFAVREDESKKKYYVLEMFPYPSG-NLHMGHVRNYSIGDVVARFKRMNGFNVLHPMGWDA  79
            +F    D SK K+Y L+MFPYPSG  LH+GH   Y+  D+++RFKR +G NVLHPMGWDA
Sbjct  22   TFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSRFKRAQGHNVLHPMGWDA  81

Query  80   FGLPAENAAIKRGVHPNDWTWSNIDNMRRQLKQLGISYDWDREVATCHPDYYKWTQWMFL  139
            FGLPAE+ A+  G +P + T  NI N +RQ++ LG+SYDWDREV T +P+YYKWTQW+F 
Sbjct  82   FGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFT  141

Query  140  QLYKNGLAYKKKAYVNWCPSCATVLANEQVV-NGVCERCKSVVGKKDLEQWFFKITDYAQ  198
            +LY +GLAY     VNW    +T +ANE+V+ +G  ER    V +K + QW +KIT YA+
Sbjct  142  KLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAE  201

Query  199  RLLDDIEKLKGWPDKVKVMQQNWIGRSEGVEVDFKVDGMDKAVRVYTTRPDTIYGVTYVV  258
            RLL+D+E + +WP+ +K MQ+NWIG+S G +V FKV + DK   V+TTRPDT++G TY V
Sbjct  202  RLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAV  260

Query  259  IAPEHPVVKELIKGTEQEQVCNEFINKMMFLNEIDRTATDVEKEGVFTGRYVINPLNGDR  318
            +APEH++V + I  ++Q +   ++  +  + +++ RT    EK GV TG Y INP+NG  
Sbjct  261  LAPEHALV-DAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAINPVNGKE  319

Query  319  VPLYLANYVLAEYGTGVVMAVPAHDQRDFEFAKKYNLPIKVVIQPEGQELDASRMTEAFV  378
            +P+ +A+YVLA YGTG +MAVPAHD+RD EFAK++NL I  V+  EG +++ +    AF 
Sbjct  320  MPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL--EGGNVEEA----AFT  373

Query  379  EVGYLVNSAEFDGVRSDEAIGKIIDYIEQKGYGKRKINYRLRDWLISRQRYWGAPIPIIY  438
            E G  +NS  +DG+    AI+K+++ +E  G G+ ++ YRLRDWL+SRQRYWG PIPII 
Sbjct  374  EDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIH  433

Query  439  CDDCGAVPVPEEDLPVILP--TDIKFSGVGESPLSTSETFISAPCPKCGKMGRRELDTMD  496
             +D  + +VPE +LP++LP   DI+ SG GESPL+     +        K GRRE +TM 
Sbjct  434  WEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK-GRRETNTMP  492

Query  497  TFVCSSWYYLRYCDPCNDKAPFDKERIRYWLPVDQYIGGVEHAILHLLYSRFLMKVLYDL  556
                SSWYYLRY DP N     D E ++ WLPVD Y+GG EHA+LHLLY+RF  KVLYDL
Sbjct  493  QWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDL  552

Query  557  GYVDYDEPFTNLLTQGMVL-------------------KDG---------------AKMS  582
            G V   EPF +L+ QGM+L                   +DG               AKMS
Sbjct  553  GVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEELEQAPAKMS  612

Query  583  KSLGNVVSPEEIIEKYGADTARLFILFASPPEKDLEWSDQGVEGCYRFINRVWRIVNEFA  642
            KSL NVV+P++++E+YGADT R++ +F +P +  + WS++G+EG  +F++RV R++    
Sbjct  613  KSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLI----  668

Query  643  DAVKEGGNIDTSTFTKADKELWYMLNNTLKRVTDDISQRFNFNTAISAVMELVNSLYYYK  702
             + KE  + +++++ K       + N+T+K VT+++ Q  +FNTAI+ +M +VN+     
Sbjct  669  -TTKEITEENSGALDK-------VYNETVKAVTEQVDQ-MKFNTAIAQLMVFVNA-----  714

Query  703  DKVADDSKNKALVREVIEKLIIMLAPFIPHATEELWSAIGKEG-SVHEQKWPSFDPAALV  761
                  +K+  L  +    ++ ++APF PH  EELW A+   G S+    WPS+D + LV
Sbjct  715  -----ANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLV  769

Query  762  KDEIEIVVQINGKVRDKIVVPSDLTKEQVEERALNSEKIKAETAGKNVVKVISVPGKLVN  821
             +++EIVVQI+GKV+ K+VV+ DL++E+++E AL +EK++AE AGK+++KVI+VP KLVN
Sbjct  770  ENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVN  829

Query  822  IVVK  825
            IV+K
Sbjct  830  IVIK  833

688) Clo1313_1020 in NC_017304


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  615 bits (2324),  Expect = 4e-177, Method: Compositional matrix adjust.
 Identities = 388/844 (46%), Positives = 560/844 (67%), Gaps = 71/844 (8%)

Query  21   AFAVREDESKKKYYVLEMFPYPSG-NLHMGHVRNYSIGDVVARFKRMNGFNVLHPMGWDA  79
            +F    D SK K+Y L+MFPYPSG  LH+GH   Y+  D+++RFKR +G NVLHPMGWDA
Sbjct  22   TFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSRFKRAQGHNVLHPMGWDA  81

Query  80   FGLPAENAAIKRGVHPNDWTWSNIDNMRRQLKQLGISYDWDREVATCHPDYYKWTQWMFL  139
            FGLPAE+ A+  G +P + T  NI N +RQ++ LG+SYDWDREV T +P+YYKWTQW+F 
Sbjct  82   FGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFT  141

Query  140  QLYKNGLAYKKKAYVNWCPSCATVLANEQVV-NGVCERCKSVVGKKDLEQWFFKITDYAQ  198
            +LY +GLAY     VNW    +T +ANE+V+ +G  ER    V +K + QW +KIT YA+
Sbjct  142  KLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAE  201

Query  199  RLLDDIEKLKGWPDKVKVMQQNWIGRSEGVEVDFKVDGMDKAVRVYTTRPDTIYGVTYVV  258
            RLL+D+E + +WP+ +K MQ+NWIG+S G +V FKV + DK   V+TTRPDT++G TY V
Sbjct  202  RLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAV  260

Query  259  IAPEHPVVKELIKGTEQEQVCNEFINKMMFLNEIDRTATDVEKEGVFTGRYVINPLNGDR  318
            +APEH++V + I  ++Q +   ++  +  + +++ RT    EK GV TG Y INP+NG  
Sbjct  261  LAPEHALV-DAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAINPVNGKE  319

Query  319  VPLYLANYVLAEYGTGVVMAVPAHDQRDFEFAKKYNLPIKVVIQPEGQELDASRMTEAFV  378
            +P+ +A+YVLA YGTG +MAVPAHD+RD EFAK++NL I  V+  EG +++ +    AF 
Sbjct  320  MPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL--EGGNVEEA----AFT  373

Query  379  EVGYLVNSAEFDGVRSDEAIGKIIDYIEQKGYGKRKINYRLRDWLISRQRYWGAPIPIIY  438
            E G  +NS  +DG+    AI+K+++ +E  G G+ ++ YRLRDWL+SRQRYWG PIPII 
Sbjct  374  EDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIH  433

Query  439  CDDCGAVPVPEEDLPVILP--TDIKFSGVGESPLSTSETFISAPCPKCGKMGRRELDTMD  496
             +D  + +VPE +LP++LP   DI+ SG GESPL+     +        K GRRE +TM 
Sbjct  434  WEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK-GRRETNTMP  492

Query  497  TFVCSSWYYLRYCDPCNDKAPFDKERIRYWLPVDQYIGGVEHAILHLLYSRFLMKVLYDL  556
                SSWYYLRY DP N     D E ++ WLPVD Y+GG EHA+LHLLY+RF  KVLYDL
Sbjct  493  QWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDL  552

Query  557  GYVDYDEPFTNLLTQGMVL-------------------KDG---------------AKMS  582
            G V   EPF +L+ QGM+L                   +DG               AKMS
Sbjct  553  GVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEELEQAPAKMS  612

Query  583  KSLGNVVSPEEIIEKYGADTARLFILFASPPEKDLEWSDQGVEGCYRFINRVWRIVNEFA  642
            KSL NVV+P++++E+YGADT R++ +F +P +  + WS++G+EG  +F++RV R++    
Sbjct  613  KSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLI----  668

Query  643  DAVKEGGNIDTSTFTKADKELWYMLNNTLKRVTDDISQRFNFNTAISAVMELVNSLYYYK  702
             + KE  + +++++ K       + N+T+K VT+++ Q  +FNTAI+ +M +VN+     
Sbjct  669  -TTKEITEENSGALDK-------VYNETVKAVTEQVDQ-MKFNTAIAQLMVFVNA-----  714

Query  703  DKVADDSKNKALVREVIEKLIIMLAPFIPHATEELWSAIGKEG-SVHEQKWPSFDPAALV  761
                  +K+  L  +    ++ ++APF PH  EELW A+   G S+    WPS+D + LV
Sbjct  715  -----ANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLV  769

Query  762  KDEIEIVVQINGKVRDKIVVPSDLTKEQVEERALNSEKIKAETAGKNVVKVISVPGKLVN  821
             +++EIVVQI+GKV+ K+VV+ DL++E+++E AL +EK++AE AGK+++KVI+VP KLVN
Sbjct  770  ENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVN  829

Query  822  IVVK  825
            IV+K
Sbjct  830  IVIK  833

689) leuS in NC_010296


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  615 bits (2322),  Expect = 5e-177, Method: Compositional matrix adjust.
 Identities = 389/852 (46%), Positives = 575/852 (68%), Gaps = 28/852 (3%)

Query  3    YNPAEIEQKWQKIWQQMGLDKTPENADKPKFYALSMFPYPSG-NLHMGHVRNYTITDVIA  61
            Y+ + IE KWQ +W +    KT  +A KPKFYAL MFPYPSG  LH+GH   YT TD+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  62   RLKRMQGYRVLHPMGWDAFGLPAENAAIERGVPPAKWTDQNIAQMKRQLQQLGLSIDWER  121
            R+KR QG  VLHPMGWDAFGLPAE+ A++ G  PA  T +NIA+ KRQ++ LG+S DW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  122  EVATCSPEYYRWTQWLFLQFFESGLAYQKEAAVNWDPIDQTVLANEQVDSEGKSWRSGAK  181
            EV T  P+YY+WTQW+F +++E GLAY+ E +VNW     T +ANE+V ++G S R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERKLLRQWFLKITDYAEQLLTDLDKLTGWPERVKTMQANWIGKSVGAYLEFPLVNSTEK  241
            V RK +RQW LKIT YAE+LL DL+ + +WPE +K MQ NWIGKS GA + F + ++   
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  242  IAVFTTRPDTVYGVTYVVLAPEHPLTLQVTTPEQKSAVETFIQEIASESELERTAEDKPK  301
            ++VFTTRPDT++G TY VLAPEH+L   +TT++Q  AV  + ++ +  S+L RT   K K
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEK  302

Query  302  RGIKTGGLAINPFTGEEIPILIADYVLYEYGTGAVMGVPAHDSRDFKFARENNLPIKIVI  361
             G+ TG+ AINP  G E+P+ IADYVL  YGTGA+M+VPAHD RD  FA++ NL I  V+
Sbjct  303  TGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL  362

Query  362  TPESGEIELKDAYTEAGIMINSAQFNGLNSQEGKTAIIDYATAQGYGKARIQYRLRDWLI  421
              E+G++E   A+TE G+ INS  ++GL+   + + +++   A+G G+  + YRLRDWL+
Sbjct  363  --EGGNVE-EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLF  419

Query  422  SRQRYWGCPIPVIHCPNCGTVPVPIDNLPVTLPENVEF--SGRGASPLAKLEDWVNVDCP  479
            SRQRYWG PIP+IH  +  + +VP  +LP+ LP   ++  SG G SPLA++ DW++V   
Sbjct  420  SRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV-TR  478

Query  480  RCGTPAKRETDTMDTFIDSSWYFLRYTDAKNEDIPFQFEKVNDWMPVDQYVGGIEHAILH  539
              G  ++RET+TM    +SSWY+LRY D+ N +   + E +++W+PVD YVGG EHA+LH
Sbjct  479  EDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLH  538

Query  540  LLYSRFFTKVLRDRGLVNVDEPFNRLLTQGMVQGLTYKNPETGKYVPAENVIYKEDKYCD  599
            LLY+RF  KVL D G+V   EPF++L+ QGM+ G +Y+++  G  V++++V  +++ + +
Sbjct  539  LLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDS-RGALVATDKVEKRDGSFFH  597

Query  600  KDTGEVLSFFFEKMSKSKYNGVDPLKVLEKYGADTARMFILFTAPPEKDLQWEDAGVEGQ  659
             +TGE L     KMSKS  N V+P  V+E+YGADT R++ +F +P +  + W + G+EG 
Sbjct  598  VETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGS  657

Query  660  FRFLNRVWRLVSEYIENKPKQVKKIETFSKTDKDLRRAIHTAIKEISEDLEGDYQFNTAI  719
             +FL+RV RL++       K++            L +  + ++K ++E+++ + +FNTAI
Sbjct  658  RKFLDRVYRLIT------TKEIT-----EENSGALDKVYNETVKAVTEQVD-QMKFNTAI  705

Query  720  SELMKLSNALG-DNKCFASPIYREGIETLLILLSLFAPHLSEELWQAL-GHNQSIHLQPW  777
            ++LM + NA   ++K F+   Y  G   ++ L++ FAPHL+EELWQAL +  +SI   PW
Sbjct  706  AQLMVFVNAANKEDKLFSD--YAKG---FVQLIAPFAPHLGEELWQALTASGESISYVPW  760

Query  778  PKVDSTALIVDEITLVIQILGKTRGTIQVPASADKSTLETLALESEIAQRYLEGKEIKKV  837
            P  D + L+ +++ +V+QI GK ++ + V+    +  L+ +AL +E  Q  + GK+I KV
Sbjct  761  PSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKV  820

Query  838  IVVPGKLVNFVV  849
            I VP KLVN+V+
Sbjct  821  IAVPNKLVNIVI  832

690) leuS in NC_003366


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  612 bits (2312),  Expect = 3e-176, Method: Compositional matrix adjust.
 Identities = 391/848 (47%), Positives = 574/848 (68%), Gaps = 58/848 (6%)

Query  6    TAIDKKWQDKWAESGLYKFDPNKEGEKLYVLEMFSYPSGSQLHAGHWFNYGPVDSWARFK  65
            TAI+ KWQ  WA++  +K + +    K+Y L+MF+YPSG+ LH GH   Y + D  +RFK
Sbjct  7    TAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSRFK  66

Query  66   RMQGYNVFQPMGFDAFGLPAENFAIKTGIHPQDSTIKNIAKMEEQLKAMGAMFNWENEVV  125
            R QG NV++PMG DAFGLPAE++A+ TG +P + T  NIA+   Q++A+G  ++W+ EV 
Sbjct  67   RAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDREVN  126

Query  126  TCSPEYYKWTQWLFLKLYEKGLAYRKKAPVNWCPSCQTVLANEQVV-DGACERCSTEVTK  184
            T  P+YYKWTQW+F KLYEKGLAY    PVNW     T +ANE+V+ DG+ ER +  V +
Sbjct  127  TTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVR  186

Query  185  KDLTQWFFKITDYADELLDKLDGLDWPEKTVSMQKHWIGRSTGSQVNFKVKDSDLNFDVF  244
            K + QW +KIT YA+ LL+ L+ +DWPE    MQ++WIG+STG++V FKVKD+D +F VF
Sbjct  187  KPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVF  246

Query  245  TTRVDTLCGVSYVVLAPENPLVDEIVSAEQKEAVENYKEEAKKQSDIERQSISREKTGVF  304
            TTR DTL G +Y VLAPE++LVD I +++Q EAV +YK +A  +SD+ R  +++EKTGV 
Sbjct  247  TTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVW  306

Query  305  TGAYAIHPLTGKEVPIWVGDYVLATYGTGAVMAVPAHDERDFAFAEKFNLPINRVIEAKD  364
            TG+YAI+P+ GKE+P+W++DYVLA+YGTGA+MAVPAHDERD  FA +FNL I  V+E+ +
Sbjct  307  TGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGN  366

Query  365  GSETNLPFCEHGILVNSGEFDGLTTDEAKEKIVEKLSSMGLGEKKVNFRLRDWLVSRQRY  424
              E+  +F E+G+ +NS+ +DGL    A  K+VE L + G+G+ +V +RLRDWL SRQRY
Sbjct  367  VEEA--AFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRY  424

Query  425  WGAPIPVVYCEECGIVPVPESQLPVELPYDVEFAPDGK--SPLAKSEAFVNTTCPHCGKP  482
            WG PIP++  E+    +VPES+LP+ LP   ++ P G   SPLA+    ++ T  +  K 
Sbjct  425  WGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK-  483

Query  483  AKRETDTLDTFVCSSWYYLRYPDNKNTEAPFNPELINKMLPVDKYVGGPEHACMHLLYAR  542
            ++RET+T+     SSWYYLRY D  NTE   + EL+++ LPVD YVGG+EHA +HLLYAR
Sbjct  484  GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYAR  543

Query  543  FITKALRDMGYLNFDEPFTSLTHQGLILGP----------------------------DG  574
            F  K L D+G +   EPF  L +QG+ILG                             + 
Sbjct  544  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEE  603

Query  575  L-----KMSKSKGNTISPDDYIKEYGADVFRMYLMFGFAYTEGGAWSDDGIKSVNRFVER  629
            L     KMSKS  N ++PDD + +YGAD +R+Y MF  +   + AWS++G+ +  +F++R
Sbjct  604  LEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR  663

Query  630  IERIIDTAREAISKGENNKTTMDKAEKELNYWRHNTIKSVTDDTDKLQFNTAIARMMEFI  689
            + R+I T++E     E+N  ++DK      Y  ++T+K+VT++ D+++FNTAIA++M F+
Sbjct  664  VYRLI-TTKEI---TEENSGALDKV-----Y--NETVKAVTEQVDQMKFNTAIAQLMVFV  712

Query  690  NALSKYTQEKEMNLDFLKDVVSDYLRLLAPFAPHFSEEQWN-LLGNSYSIFNEAWPKFDP  748
            NA +K  ++K     ++ D   ++++L+APFAPH++EE W+ L +++ SI   +WP +D 
Sbjct  713  NAANK--EDK-----LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDE  765

Query  749  KALVKDEVEIAIQVNGKIKNKIMVSSDLDEEGIKAAALADEKIIASTEGKTvvkvivikG  808
              LV ++VEI +Q++GK+K K++V+ DL  E ++  ALA+EK+ A   GK ++KVI +  
Sbjct  766  SKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPN  825

Query  809  RLVNIVVK  816
            +LVNIV+K
Sbjct  826  KLVNIVIK  833

691) leuS in NC_008262


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  612 bits (2312),  Expect = 3e-176, Method: Compositional matrix adjust.
 Identities = 391/848 (47%), Positives = 574/848 (68%), Gaps = 58/848 (6%)

Query  6    TAIDKKWQDKWAESGLYKFDPNKEVEKLYVLEMFSYPSGSQLHAGHWFNYGPVDSWARFK  65
            TAI+ KWQ  WA++  +K + +    K+Y L+MF+YPSG+ LH GH   Y + D  +RFK
Sbjct  7    TAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSRFK  66

Query  66   RMQGYNVFQPMGFDAFGLPAENFAIKTGIHPQDSTIKNIAKMEEQLKAMGAMFNWENEVV  125
            R QG NV++PMG DAFGLPAE++A+ TG +P + T  NIA+   Q++A+G  ++W+ EV 
Sbjct  67   RAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDREVN  126

Query  126  TCSPEYYKWTQWLFLKLYEKGLAYRKKAPVNWCPSCQTVLANEQVV-DGACERCSTEVTK  184
            T  P+YYKWTQW+F KLYEKGLAY    PVNW     T +ANE+V+ DG+ ER +  V +
Sbjct  127  TTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVR  186

Query  185  KDLTQWFFKITDYADELLDKLDGLDWPEKTVSMQKHWIGRSTGSQVNFKVKDSDLNFDVF  244
            K + QW +KIT YA+ LL+ L+ +DWPE    MQ++WIG+STG++V FKVKD+D +F VF
Sbjct  187  KPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVF  246

Query  245  TTRVDTLCGVSYVVLAPENPLVDEIVSAEQKEAVENYKEEAKKQSDIERQSISREKTGVF  304
            TTR DTL G +Y VLAPE++LVD I +++Q EAV +YK +A  +SD+ R  +++EKTGV 
Sbjct  247  TTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVW  306

Query  305  TGAYAIHPLTGKEVPIWVGDYVLATYGTGAVMAVPAHDERDFAFAEKFNLPINRVIEAKD  364
            TG+YAI+P+ GKE+P+W++DYVLA+YGTGA+MAVPAHDERD  FA +FNL I  V+E+ +
Sbjct  307  TGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGN  366

Query  365  GSETNLPFCEHGILVNSGEFDGLTTDEAKEKIVEKLASMGLGEKKVNFRLRDWLVSRQRY  424
              E+  +F E+G+ +NS+ +DGL    A  K+VE L + G+G+ +V +RLRDWL SRQRY
Sbjct  367  VEEA--AFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRY  424

Query  425  WGAPIPVVYCEECGIVPVPESQLPVELPYDVEFAPDGK--SPLAKSEAFVNTTCPHCGKP  482
            WG PIP++  E+    +VPES+LP+ LP   ++ P G   SPLA+    ++ T  +  K 
Sbjct  425  WGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK-  483

Query  483  AKRETDTLDTFVCSSWYYLRYPDNKNTEAPFNPELINKMLPVDKYVGGPEHACMHLLYAR  542
            ++RET+T+     SSWYYLRY D  NTE   + EL+++ LPVD YVGG+EHA +HLLYAR
Sbjct  484  GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYAR  543

Query  543  FITKALRDMGYLNFDEPFTSLTHQGLILGP----------------------------DG  574
            F  K L D+G +   EPF  L +QG+ILG                             + 
Sbjct  544  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEE  603

Query  575  L-----KMSKSKGNTISPDDYIKEYGADVFRMYLMFGFAYTEGGAWSDDGIKSVNRFVER  629
            L     KMSKS  N ++PDD + +YGAD +R+Y MF  +   + AWS++G+ +  +F++R
Sbjct  604  LEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR  663

Query  630  IERIIDTAREAISKGENNKTTMDKAEKELNYWRHNTIKSVTDDTDKLQFNTAIARMMEFI  689
            + R+I T++E     E+N  ++DK      Y  ++T+K+VT++ D+++FNTAIA++M F+
Sbjct  664  VYRLI-TTKEI---TEENSGALDKV-----Y--NETVKAVTEQVDQMKFNTAIAQLMVFV  712

Query  690  NALSKYTQEKEMNLDFLKDVVSDYLRLLAPFAPHFSEEQWN-LLGNSYSIFNEAWPKFDP  748
            NA +K  ++K     ++ D   ++++L+APFAPH++EE W+ L +++ SI   +WP +D 
Sbjct  713  NAANK--EDK-----LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDE  765

Query  749  KALVKDEVEIAIQVNGKIKNKIMVSSDLDEEGIKAAALADEKIIASTEGKTvvkvivikG  808
              LV ++VEI +Q++GK+K K++V+ DL  E ++  ALA+EK+ A   GK ++KVI +  
Sbjct  766  SKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPN  825

Query  809  RLVNIVVK  816
            +LVNIV+K
Sbjct  826  KLVNIVIK  833

692) GEI7407_0169 in NC_019703


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  612 bits (2311),  Expect = 4e-176, Method: Compositional matrix adjust.
 Identities = 384/864 (45%), Positives = 580/864 (68%), Gaps = 39/864 (4%)

Query  5    YNPSAIEEKWQQTWADQGLDKAPESSDKPKFYALSMFPYPSG-NLHMGHVRNYTITDVIA  63
            Y+ +AIE KWQ  WAD+   K+   + KPKFYAL MFPYPSG  LH+GH   YT TD+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RLKRMQGHRVLHPMGWDAFGLPAENAAIDRGIHPATWTYQNIDQMRQQLQQLGLSYDWDR  123
            R+KR QGH VLHPMGWDAFGLPAE+ A+D G +PA  T +NI + ++Q++ LG+SYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVATCSPDYYRWTQWIFLQFFQAGLAYQKESAVNWDPIDQTVLANEQVDNEGRSWRSGAK  183
            EV T  P+YY+WTQWIF ++++ GLAY+ E +VNW     T +ANE+V  +G S R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  184  VERKLLRQWFFKITDYAEQLLADLDTLDGWPDRVKTMQANWIGKSTGATLEFPIVGLDEK  243
            V RK +RQW +KIT YAE+LL DL+ +D WP+ +K MQ NWIGKSTGA + F + + D  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  244  IAVFTTRPDTVYGVTYVVLAPEHPLTAQVTTPDRAAAVEAFVKEISSESEIERTAEDKPK  303
            ++VFTTRPDT++G TY VLAPEH+L   +TT+D+A AV  + ++ S  S++ RT   K K
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEK  302

Query  304  RGISTGGKAINPFTGEEIPIWIADYVLYEYGTGAVMGVPAHDVRDFQFAQRNQLPIKTVV  363
             G+ TG+ AINP  G E+P+WIADYVL  YGTGA+M+VPAHD RD +FA++ +L I  V+
Sbjct  303  TGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL  362

Query  364  IPAGGDASQPLTAAYTEAGVLVNSGTFDGTPSTEGKTQIVAYAEEQGFGKARIQYRLRDW  423
               GG+  +   AA+TE G+ +NS+ +DG   + + +++V   E +G G+  + YRLRDW
Sbjct  363  --EGGNVEE---AAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDW  417

Query  424  LISRQRYWGVPIPVVHCPSCGAVPVPEDQLPVRLPENVEF--SGRGPSPLAKLTDWINVP  481
            L+SRQRYWG PIP++H     + +VPE +LP+ LP   ++  SG G SPLA++TDW++V 
Sbjct  418  LFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT  477

Query  482  CPSCGEPAQRETDTMDTFIDSSWYFLRYTDARNENQPFAKDKVNRWMGVDQYVGGIEHAI  541
                G  ++RET+TM    +SSWY+LRY D++N ++    + +++W+ VD YVGG EHA+
Sbjct  478  RED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  542  LHLLYSRFFTKVLRDRGLVDVDEPFKRLLTQGMVQAMTYKNPTTGKYIPAAEVDFSDPQA  601
            LHLLY+RF  KVL D G+V   EPF++L+ QGM+ + +Y++ + G  +++  V+  D   
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRD-SRGALVATDKVEKRDGSF  595

Query  602  PKDPATGDRLEVFYEKMSKSKYNGVDPKEVLAKYGADTARMFILFKAPPEKDLEWDDADV  661
              +  TG+ LE    KMSKS  N V+P +V+ +YGADT R++ +F +P +  + W + ++
Sbjct  596  F-HVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGL  654

Query  662  EGQFRFLNRVWRLVSEFaaanqtqlaaaaiaaqlqgqNDSLTKADKDLRRAIHTAIQAVT  721
            EG  +FL+RV RL++                      ++        L +  + +++AVT
Sbjct  655  EGSRKFLDRVYRLIT---------------------TKEITEENSGALDKVYNETVKAVT  693

Query  722  EDLEGDYQFNTAVSEMMKLSNALSDAPAKDTPVYAEGIRALVLLLAPFAPHIAEELWH-L  780
            E+++ + +FNTA++++M     + +A+ K+  ++++  +++V L+APFAPH++EELW+ L
Sbjct  694  EQVD-QMKFNTAIAQLM----VFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQAL  748

Query  781  LGNQVSVHEQAWPQYDPAALVADEITLVIQILGKTRGTIQVPAQADKAALEQYARNSEVA  840
             ++  S+   +WP YD + LV +++ +V+QI GK ++ + V+ +  +  L++ A  +E  
Sbjct  749  TASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKV  808

Query  841  QRYIEGKEIKKVIVVPGKLVNFVV  864
            Q  I GK+I KVI VP KLVN+V+
Sbjct  809  QAEIAGKDIIKVIAVPNKLVNIVI  832

693) Oscil6304_4513 in NC_019693


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  611 bits (2309),  Expect = 6e-176, Method: Compositional matrix adjust.
 Identities = 383/853 (45%), Positives = 586/853 (69%), Gaps = 30/853 (3%)

Query  5    YNPASLEEKWQQTWTERQLYQTPETRDRPKFYALSMFPYPSGS-LHMGHVRVYTITDVIG  63
            Y+ +++E KWQ  W++ + ++T     +PKFYAL MFPYPSG+ LH+GH   YT TD+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RLKRMQGYRVLNPMGWDAFGLPAENAAIERGIHPAKWTYQNIAQMKQQLERLGIAFDWTR  123
            R+KR QG  VL+PMGWDAFGLPAE+ A++ G +PA  T +NIA+ K+Q++ LG+++DW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVATCSPDYYKWTQWIFLQFFNAGLAYQKEAAVNWDPIDQTVLANEQVDNEGRSWRSGAK  183
            EV T  P+YYKWTQWIF ++++ GLAY+ E +VNW     T +ANE+V  +G S R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  184  VERKLLKQWFFKITDYAEQLLQDLDQLTGWPERVKLMQANWIGKSVGAYLEFPIVDSTEK  243
            V RK ++QW +KIT YAE+LL+DL+++ +WPE +K MQ NWIGKS GA + F + D+   
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  244  VAVFTTRPDTVYGVTYVVLAPEHPLTRQVTTSDRLAAVESFIAEVSNQSELERTADDKPK  303
             +VFTTRPDT++G TY VLAPEH+L   +TTSD+  AV  +  + S +S+L RT   K K
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEK  302

Query  304  RGIPTGGTAINPFTGEEIPIWIADYVLYEYGTGAVMGVPAHDVRDFKFAREQNLPIKQVI  363
             G+ TG+ AINP  G E+P+WIADYVL  YGTGA+M+VPAHD RD  FA++ NL I  V+
Sbjct  303  TGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL  362

Query  364  VRADAADEKAQLKEAYTEPGIVINSELFNGMESPTAKGEIIAYAEKQKWGKARVQYRLRD  423
              ++  +       A+TE G+ INS++++G++ ++A + ++   E +  G+  V YRLRD
Sbjct  363  EGGNVEE------AAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  424  WLISRQRYWGAPIPVIHCPSCGAVPVPDEDLPVQLP--EDVAFSGRGLSPLSQLESWVNV  481
            WL+SRQRYWG PIP+IH     + +VP+ +LP+ LP   D+  SG G SPL+++  W++V
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  482  PCPSCGEPAKRETDTMDTFIDSSWYFLRYPDAQNADKAFDTQQVNDWLPVDQYVGGIEHA  541
                 G  ++RET+TM    +SSWY+LRY D++N++K  D + +++WLPVD YVGG EHA
Sbjct  477  TRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  542  ILHLLYSRFFTKVLRDRGLLNFDEPFQRLLTQGMVQGLTYKNPQTGKYIPSAQVNASDPK  601
            +LHLLY+RF  KVL D G++   EPFQ+L+ QGM+ G +Y++++ G  +++ +V+  D  
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSR-GALVATDKVEKRDGS  594

Query  602  --DPEMGEPLQVFYEKMSKSKYNGVDPLEVLGNYGADTARMFILFKAPPEKDLEWEDADV  659
              + E GE L+    KMSKS  N V+P +V+ +YGADT R++ +F +P +  + W + ++
Sbjct  595  FFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGL  654

Query  660  EGQFRFLNRVWRLVTEYAETTPAKQVKGELSKAEKELRRAIHTAIKEITEDLDGEYQFNT  719
            EG  +FL+RV RL+T       +K++  E S A   L +  + ++K +TE++D + +FNT
Sbjct  655  EGSRKFLDRVYRLIT-------TKEITEENSGA---LDKVYNETVKAVTEQVD-QMKFNT  703

Query  720  AVSELMKLSNALNDADCKNSAIYTEGIKTLLILLAPFAPHIAEELWQGI-GNQTSVHEQS  778
            A+++LM     + +A  K+  ++++  K ++ L+APFAPH++EELWQ++ ++  S+   +
Sbjct  704  AIAQLM----VFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVP  759

Query  779  WPGVDLDALVVDEITLVIQISGKTRGTIQVPAQATREELEQYARESEVAQKYIAGQEIKK  838
            WP+ D   LV +++ +V+QI GK ++ + V+ + +REEL++ A  +E  Q  IAG++I K
Sbjct  760  WPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIK  819

Query  839  AIVVPGKLVNFVL  851
             I VP KLVN+V+
Sbjct  820  VIAVPNKLVNIVI  832

694) Cyan7822_5283 in NC_014501


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  611 bits (2308),  Expect = 7e-176, Method: Compositional matrix adjust.
 Identities = 375/854 (44%), Positives = 583/854 (69%), Gaps = 31/854 (3%)

Query  5    YNAEAIEKKWQQTWVEMGIDKTPEDKTKPKYYALSMFPYPSG-NLHMGHVRNYVITDVIA  63
            Y+  AIE KWQ  W +    KT  D +KPK+YAL MFPYPSG  LH+GH   Y  TD+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RLKRMQGHRVLHPMGWDAFGLPAENAAIERGIHPAKWTYQNIAQMKQQLQQLGLSIDWNR  123
            R+KR QGH VLHPMGWDAFGLPAE+ A++ G +PA  T +NIA+ K+Q++ LG+S DW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVTTCSPDYYKWTQWLFLQFFQAGLAYQKEAAVNWDPIDQTVLANEQVDAEGKSWRSGAK  183
            EV T  P+YYKWTQW+F ++++ GLAY+ E +VNW     T +ANE+V ++G S R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  184  VERKLLRQWFLKITDYAEQLLNDLDKLTGWPERVKLMQANWIGKSIGAYLEFPVVGMDEK  243
            V RK +RQW LKIT YAE+LL+DL+ + +WPE +K MQ NWIGKS GA + F V + D  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  244  IAVFTTRPDTVYGVTYVVLAPEHPLTPKVTTPKNKKAVEKFIKEVTSESEIERTAEDKPK  303
            ++VFTTRPDT++G TY VLAPEH+L   +TT+ +  AV  + ++ +  S++ RT   K K
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEK  302

Query  304  KGILTGGKAINPFTGEQVPILIANYVLYEYGTGAVMGVPAHDVRDFKFAKENKLPIRVVI  363
             G+ TG+ AINP  G ++P+ IA+YVL  YGTGA+M+VPAHD RD  FAK+ +L I  V+
Sbjct  303  TGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL  362

Query  364  VPEDAGDKDTPLTEAYTDPGIMVNSDSFNGMDSTKGKTAIIDYAENNGFGKARVQYRLRD  423
               +  +       A+T+ G+ +NSD ++G+D + + + +++  E +G G+  V YRLRD
Sbjct  363  EGGNVEE------AAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  424  WLISRQRYWGCPIPVIHCPSCGTVPVPDADLPVKLP--EDVEFSGRGASPLAKLDHWINV  481
            WL+SRQRYWG PIP+IH     + +VP+++LP+ LP   D+  SG G SPLA++ +W++V
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  482  SCPSCGEPAKRETDTMDTFIDSSWYFLRYSDANNEQEAFNLKEVNDWMAVDQYVGGIEHA  541
            +    G  ++RET+TM    +SSWY+LRY D++N +   +   +++W++VD YVGG EHA
Sbjct  477  TRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  542  ILHLLYSRFFTKVVRDRGLVNIDEPFQRLLTQGMVQGMTYKNPKTGKYIPSAQVNPNDPK  601
            +LHLLY+RF  KV+ D G+V   EPFQ+L+ QGM+ G +Y++++ G  +++ +V+  D  
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSR-GALVATDKVEKRDGS  594

Query  602  --DPETGDPLEVFYEKMSKSKYNGVDPKQVLGKYGADTARMFILFKAPPEKDLEWDDADV  659
              + ETG+ LE    KMSKS  N V+P +V+ +YGADT R++ +F +P +  + W + ++
Sbjct  595  FFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGL  654

Query  660  EGQFRFLNRVWRLVGDYIANHKPSKKKNDSLTKVEQDLRRAIHIAIKEISDDLEGEYQFN  719
            EG  +FL+RV RL    I+    +  ++++L KV ++       ++K ++++++ + +FN
Sbjct  655  EGSRKFLDRVYRL----ITTKEITEENSGALDKVYNE-------TVKAVTEQVD-QMKFN  702

Query  720  TAVSELMKLNNALSEAKCYESPVYTEGVETLLILLAPFAPHIAEELWHQL-GNSDSVHRQ  778
            TA+++LM + NA +     E  ++++    ++ L+APFAPH++EELW+ L ++++S+   
Sbjct  703  TAIAQLMVFVNAANK----EDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYV  758

Query  779  SWPQFDPSALVVDEITLVIQVMGKTRGTIQVPSSASKEELEKLALNSELAQRYLKDQEVK  838
            +WP +D S LV +++ +V+Q+ GK ++ + V+   S+EEL+ +AL +E  Q  + ++++ 
Sbjct  759  PWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDII  818

Query  839  KVIVVPGKLVNFVV  852
            KVI VP KLVN+V+
Sbjct  819  KVIAVPNKLVNIVI  832

695) Sta7437_1821 in NC_019748


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  610 bits (2303),  Expect = 2e-175, Method: Compositional matrix adjust.
 Identities = 381/853 (45%), Positives = 579/853 (68%), Gaps = 31/853 (3%)

Query  5    YNATEIEPKWQKTWAESETDRTPETPNKSKYYALSMFPYPSGS-LHMGHVRNYVITDVIA  63
            Y+ T IEPKWQ  WA+++T +T   ++K+K+YAL MFPYPSG+ LH+GH   Y  TD+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RLKRMQGYRVLHPMGWDAFGLPAENAAIDRGVPPAQWTYQNIAQMRSQLQQLGLSIDWER  123
            R+KR QG  VLHPMGWDAFGLPAE+ A+D G  PA+ T +NIA+ + Q++ LG+S DW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVATCSPDYYHWTQWLFLQFFQAGLAYQREAAVNWDPIDQTVLANEQVDSEGRSWRSGAK  183
            EV T  P+YY WTQW+F ++++ GLAY+ E +VNW     T +ANE+V ++G S R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  184  VERKLLKQWFFKITDYAEQLLNDLDKLTGWPDRVKLMQANWIGKSVGAYLEFPIIGMDEK  243
            V RK ++QW +KIT YAE+LL+DL+ + +WP+ +K MQ NWIGKS GA + F + + D  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  244  IGVFTTRPDTVYGVTYVVLAPEHPLTPQVTTSDRKEAVEAFIKEVKNESEIERTAEDKPK  303
            + VFTTRPDT++G TY VLAPEH+L   +TTSD+ EAV  + ++    S++ RT   K K
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEK  302

Query  304  RGILTGGKAINPFNGSEIPILIADYVLYEYGTGAVMGVPAHDTRDFKFAKENNLPIQVVI  363
             G+ TG+ AINP NG E+P+ IADYVL  YGTGA+M+VPAHD RD  FAK+ NL I  V+
Sbjct  303  TGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL  362

Query  364  VPEKTNDPGELQNAYIEPGIMVNSGQFDGTSSETGKTKIIEYAEAKGYGKARIQYRLRDW  423
               + +++     A+ E G+ +NS+ +DG    ++ +K++E  EA G G+  + YRLRDW
Sbjct  363  EGGNVEEA-----AFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDW  417

Query  424  LISRQRYWGCPIPVIHCPSCGTVPVPDADLPVQLPEQVEF--SGRGPSPLAKLSDWVNVP  481
            L+SRQRYWG PIP+IH     + +VP+++LP+ LP   ++  SG G SPLA+++DW++V 
Sbjct  418  LFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT  477

Query  482  CPSCGEPAKRETDTMDTFIDSSWYFLRYSDAKNPDSAFAKDKVNDWMPVDQYVGGIEHAI  541
                G  ++RET+TM    +SSWY+LRY D+ N +     + +++W+PVD YVGG EHA+
Sbjct  478  RED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  542  LHLLYSRFFTKVLRDRGLLDFDEPFQRLLTQGMVQGITYKNPTTGKYIPSAEVNPEDPK-  600
            LHLLY+RF  KVL D G++   EPFQ+L+ QGM+ G +Y++ + G  +++  V+  D   
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRD-SRGALVATDKVEKRDGSF  595

Query  601  -DPETSEALSVFYEKMSKSKYNGVDPQQVLAKYGADTARMFILFKAPPEKDLEWDDADVE  659
             + ET+E L     KMSKS  N V+P++V+ +YGADT R++ +F +P +  + W + ++E
Sbjct  596  FHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLE  655

Query  660  GQFRFLNRVWTQVTEYNSSQTTSSENKELTKAEKD-LRRAIHTAIKEVSEDLEGEYQFNT  718
            G  +FL+RV   +T            KE+T  + + L +  + ++K V+E+++ + +FNT
Sbjct  656  GSRKFLDRVYRLIT-----------TKEITEENSGALDKVYNETVKAVTEQVD-QMKFNT  703

Query  719  AVSELMKLSNALKEASCKDSPVYHEGIEALVILLAPFAPHLAEELWQQL-GHTDSVHHQS  777
            A+++LM     + +A+ K+  ++ +   ++V L+APFAPHL+EELWQ L +  +S+   +
Sbjct  704  AIAQLM----VFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVP  759

Query  778  WLKVDSNALVVDEITLVIQIMGKTRGTIQVPANLNKAELETYALQSEMAQRYLEGKEVKK  837
            W   D + LV +++ +V+QI GK ++ + V+ +L++ EL+  AL +E  Q  + GK++ K
Sbjct  760  WPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIK  819

Query  838  VIVVPNKLVNFVV  850
            VI VPNKLVN+V+
Sbjct  820  VIAVPNKLVNIVI  832

696) Mesil_1033 in NC_014212


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  609 bits (2302),  Expect = 2e-175, Method: Compositional matrix adjust.
 Identities = 405/876 (47%), Positives = 582/876 (67%), Gaps = 51/876 (5%)

Query  5    YNPHELEPKWQRYWQEIGLLKA-TEGSEKKSYILVMFPYPSG-DLHMGHLKNYTMGDVLA  62
            Y+   +EPKWQ +W +   +K+ T++S  K Y L MFPYPSG +LH+GH   YT  D+L+
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RFRTQQGYSVLHPFGWDAFGLPAENAALKFGVSPADWTFGNIQQSKESLALMGIQYDWSR  122
            RF+  QG +VLHP GWDAFGLPAE+ A+  G  PA+ T  NI + K  +  +G+ YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVTTCTPEYYKWNQWIFLKMYERGLAYRKKSYVNWDPVEQSVLANEQVI-DGRGWRSGAL  181
            EV T  P+YYKW QWIF K+YE+GLAY     VNW     + +ANE+V+ DG + R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VEKRELEQWYLKITDYAERLLADLDKLPRWPEKVKAMQRAWIGKSTGAEFDFQVKGHDVK  241
            V ++ + QW LKIT YAERLL DL+ +  WPE +K MQR WIGKSTGA+  F+VK+ D  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  242  IRVFSTRPDTIFGATFMVLAPEHELVARITTPEQKEAVEAYVAATRMKSEVERQREDREK  301
            + VF+TRPDT+FGAT+ VLAPEH LV  ITT++Q EAV  Y   + +KS++ R    +EK
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEK  302

Query  302  TGVFTGAYAINPASGKEIPIWIADYVLSGYGTGAIMGVPGQDERDWEFAEQFGLEIIRTV  361
            TGV TG+YAINP +GKE+P+WIADYVL++YGTGAIM+VP++DERDWEFA QF L+II  +
Sbjct  303  TGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL  362

Query  362  EPPAGWQGKAYTEDGPAINSGFLNGLHVEEAKKKIIEWMQEKGIGEGKVNYRLRDWLISR  421
            E     +  A+TEDG  INS+FL+GL+   A  K++EW++  G+G+ +V YRLRDWL+SR
Sbjct  363  EGGNV-EEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSR  421

Query  422  QRYWGTPIPMIHCDSCGIVPVPYEQLPVVLPTLKDVEDIRPKGK--SPLAAHPEFYETTC  479
            QRYWG PIP+IH +     +VP  +LP+VLP  K   DIRP G   SPLA   +  E T 
Sbjct  422  QRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTK---DIRPSGTGESPLANVTDWLEVTR  478

Query  480  PKCGGKARRdtdtmdtffdSSWYFLRYTDAHNEHLPFDPERANFWMPVDQYIGGVEHAIL  539
               G K+RR+T+TM    +SSWY+LRY D+HN +   D E  + W+PVD Y+GG EHA+L
Sbjct  479  ED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVL  537

Query  540  HLLYSRFFTKFLHDLGMVKVEEPFEGLFTQGMVMGWTDVGAVEVKDGQIRFLSSERRAKL  599
            HLLY+RF  K L DLG+V   EPF+ LF QGM++G         +D++  ++++++  K 
Sbjct  538  HLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILG------TSYRDSRGALVATDKVEKR  591

Query  600  DLPETLSVEEAKKSGAELRTHDDGSIHFWKPATMSKSLGNGVMVGPFVKEQGADIARITI  659
            D    + VE    +G EL            PA MSKSL N V  +  V + GAD  R+  
Sbjct  592  D-GSFFHVE----TGEELEQ---------APAKMSKSLKNVVNPDDVVEQYGADTLRVYE  637

Query  660  LFAAPPENEMIWTEEGVQGSWRYLNRVWRRVAEDRAELGKTSDHFEAQALGGADKALYQK  719
            +F +P +  + W+EEG++GS+++L+RV R +         T+ ++  +  G+ DK +Y  
Sbjct  638  MFMGPLDASIAWSEEGLEGSRKFLDRVYRLI---------TTKEITEENSGALDK-VY--  685

Query  720  LHQTLKKVGEDIEALRFNTAVAALMELLNTLYDYRKENPVSPVYRTAIRYYLQMLAPFAP  779
             ++T+K V E+++ ++FNTA+A LM ++N+     KE+ + + Y  +   ++Q++APFAP
Sbjct  686  -NETVKAVTEQVDQMKFNTAIAQLMVFVNAA---NKEDKLFSDYAKG---FVQLIAPFAP  738

Query  780  HLAEELWHWFDWGQGQSVFAARWPEVDPEALLADSFELVVQVSGKVRGKVIVPTGASEDE  839
            HL+EELW+ +  + G+S+    WP  D   L+ +  E+VVQ+ GKV++K++V+ + S +E
Sbjct  739  HLGEELWQALT-ASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREE  797

Query  840  IRRIAREIPNVQAHLEGKQVVKEIYVPGKLLNIVVR  875
            ++ +A    +VQA++ GK+++K I VP KL+NIV++
Sbjct  798  LQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

697) ANA_C12101 in NC_019427


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  609 bits (2300),  Expect = 3e-175, Method: Compositional matrix adjust.
 Identities = 388/855 (46%), Positives = 582/855 (69%), Gaps = 32/855 (3%)

Query  9    YQPAAIEEKWQQTWLELGLDKTPQDTNKPKFYALSMFPYPSGS-LHMGHVRNYTITDVIA  67
            Y+ +AIE KWQ  W +    KT  D++KPKFYAL MFPYPSG+ LH+GH   YT TD+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  68   RLKRMQGYRVLHPMGWDAFGLPAENAAIDRGVPPAKWTYQNIAQMRQQLQRLGLSLDWET  127
            R+KR QG  VLHPMGWDAFGLPAE+ A+D G  PA  T +NIA+ ++Q++ LG+S DW+ 
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  128  ELATCSPDYYKWTQWIFLQFLQAGLAYQREAAVNWDPIDQTVLANEQVDNEGRSWRSGAI  187
            E+ T  P+YYKWTQWIF ++ + GLAY+ E +VNW     T +ANE+V  +G S R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  188  VERKLLRQWFFKITDYAEELLNDLDKLTGWPERVKLMQANWIGKSTGAYLEFPIVGLDEK  247
            V RK +RQW +KIT YAE LL+DL+ + +WPE +K MQ NWIGKSTGA + F + + D  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  248  IGVYTTRPDTVYGVSYVVLAPEHPLTQVVTTSDQKAAVAAFIKEVSNQSELERTAEDKPK  307
            + V+TTRPDT++G +Y VLAPEH+L + +TTSDQ  AVA + ++ S +S+L RT   K K
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEK  302

Query  308  RGIPTGGKVVNPFTGEEVPIWIADYVLYEYGTGAVMGVPAHDVRDFKFAKEQNLAIKVVI  367
             G+ TG+  +NP  G E+P+WIADYVL  YGTGA+M+VPAHD RD  FAK+ NL     I
Sbjct  303  TGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLD----I  358

Query  368  VPEIGAEETLKSAYTETGILVNSGDFNGMNSVDAKKAIIEFAENQNFGKLRIQYRLRDWL  427
            +P + + +   +A+TE G+ +NS+ ++G++   A   ++E  E +  G+  + YRLRDWL
Sbjct  359  IPVLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWL  418

Query  428  ISRQRYWGAPIPVIHCPECGIVPVADKDLPVQLP--EDIELSGRGGSPLAQLESWVNVTC  485
            +SRQRYWG PIP+IH  +    +V++ +LP+ LP   DI  SG G SPLA++  W++VT 
Sbjct  419  FSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTR  478

Query  486  PSCGTPAKRETDTMDTFIDSSWYFLRYPDAKNEEKIFDSGKVNDWMPVDQYVGGIEHAIL  545
               G  ++RET+TM    +SSWY+LRY D+ N EK+ D   +++W+PVD YVGG EHA+L
Sbjct  479  ED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVL  537

Query  546  HLLYSRFFTKVLRDRGLFNFDEPFQKLLTQGMVQGLTYMNPNKGGKDKWIPSNLVDANNP  605
            HLLY+RF  KVL D G+    EPFQKL+ QGM+ G +Y    +++++  ++++ V+  + 
Sbjct  538  HLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY----RDSRGALVATDKVEKRDG  593

Query  606  --IDPQTGEPLQRLYATMSKSKGNGVAPEDVINKYGIDTARMFILFKAPPEKDLEWDEAD  663
              ++ +TGE L++  A MSKS  N V P+DV+++YG DT R++ +F +P +  + W E +
Sbjct  594  SFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEG  653

Query  664  VEGQFRFLNRVWRLVTDYAASPKQLTNDNGQLTKAEKDLRRFIHIAIQAITEDVVDEYQF  723
            +EG  +FL+RV RL+T      K++T++N+        L +  + +++A+TE+ VD+ +F
Sbjct  654  LEGSRKFLDRVYRLIT-----TKEITEENSG------ALDKVYNETVKAVTEQ-VDQMKF  701

Query  724  NTAISELMKLSNALTDADCHNSPIYAEGMQTLVIMLAPFAPHIGDELWQ-LLGNKNSVHT  782
            NTAI++LM     + +A   +  ++++  + +V ++APFAPH+G+ELWQ L ++ +S+  
Sbjct  702  NTAIAQLM----VFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISY  757

Query  783  QTWPSFDPAALIADEITLVIQIMGKTRGAIQVPSQSDKAELEKYARESEAGQRYLEGKEI  842
              WPS+D + L+ +++ +V+QI GK ++ + V+ +  + EL+  A  +E  Q  + GK+I
Sbjct  758  VPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDI  817

Query  843  KKVIVVPGKLVNFVL  857
             KVI VP KLVN+V+
Sbjct  818  IKVIAVPNKLVNIVI  832

698) Anacy_3413 in NC_019771


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  609 bits (2300),  Expect = 3e-175, Method: Compositional matrix adjust.
 Identities = 387/859 (46%), Positives = 580/859 (68%), Gaps = 33/859 (3%)

Query  6    KTLYHPAAIEEKWQKTWLELGLDKTPQDQNKPKFYALSMFPYPSGS-LHMGHVRNYTITD  64
             T+Y+ +AIE KWQ  W +    KT  D +KPKFYAL MFPYPSG+ LH+GH   YT TD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  65   VIARLKRMQGYRVLHPMGWDAFGLPAENAAIDRGVPPAKWTYQNIAQMRQQLQRLGLSLD  124
            +++R+KR QG  VLHPMGWDAFGLPAE+ A+D G  PA  T +NIA+ ++Q++ LG+S D
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  125  WECEVATCSPDYYKWTQWIFLQFLQAGLAYQREAAVNWDPIDQTVLANEQVDNEGRSWRS  184
            W+ EV T  P+YYKWTQWIF ++ + GLAY+ E +VNW     T +ANE+V  +G S R+
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  185  GAIVERKLLRQWFFKITDYAEELLNDLDKLTGWPERVKLMQANWIGKSTGAYLEFPIVGS  244
            G  V RK +RQW +KIT YAE LL+DL+ + +WPE +K MQ NWIGKSTGA + F + ++
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDT  239

Query  245  EEKIGVYTTRPDTVYGVSYVVLAPEHPLTQIVTTSEQKAAVEAFIKEVSNQSELERTAED  304
            +  + V+TTRPDT++G +Y VLAPEH+L + +TTS+Q  AV  + ++ S +S+L RT   
Sbjct  240  DKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA  299

Query  305  KPKRGIPTGGKVVNPFTGEEVPVWIADYVLYEYGTGAVMGVPAHDVRDFKFAKEQNLAIK  364
            K K G+ TG+  +NP  G E+PVWIADYVL  YGTGA+M+VPAHD RD  FAK+ NL   
Sbjct  300  KEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLD--  357

Query  365  VVIVPEVGAEETLKSAYTEAGILVNSGDFNGMNSLEAKKAIIEFAEKQNFGKLRIQYRLR  424
              I+P + + +   +A+TE G+ +NS+ ++G++   A   ++E  E +  G+  + YRLR
Sbjct  358  --IIPVLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  425  DWLISRQRYWGAPIPVIHCPNCGIVPVPDADLPVQLP--EDIELSGRGGSPLAQLESWVN  482
            DWL+SRQRYWG PIP+IH  +    +VP+++LP+ LP   DI  SG G SPLA++  W++
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  483  VPCPTCGTPAKRETDTMDTFIDSSWYYLRYADAKNEEKIFDSSKVNDWMPVDQYVGGIEH  542
            V     G  ++RET+TM    +SSWYYLRY D+ N EK+ D   +++W+PVD YVGG EH
Sbjct  476  VTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEH  534

Query  543  AILHLLYSRFFTKVLRDRGLFNFDEPFQRLLTQGMVQGLTYMNPNKGGKDKWIPSHLVDA  602
            A+LHLLY+RF  KVL D G+    EPFQ+L+ QGM+ G +Y    +++++  ++++ V+ 
Sbjct  535  AVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY----RDSRGALVATDKVEK  590

Query  603  NNPV--DPQTGEPLQRLYATMSKSKGNGVAPEDVINKYGIDTARMFILFKAPPEKDLEWD  660
             +    + +TGE L++  A MSKS  N V P+DV+++YG DT R++ +F +P +  + W 
Sbjct  591  RDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWS  650

Query  661  EADVEGQFRFLNRVWRLVTDYAAAGVCKQKAELDKLSKVEKDLRRAIHIAIQAITEDVED  720
            E ++EG  +FL+RV RL+T   +  +  +++           L +  + +++A+TE+V D
Sbjct  651  EEGLEGSRKFLDRVYRLIT---TKEITEENSG---------ALDKVYNETVKAVTEQV-D  697

Query  721  EYQFNTAISELMKLSNALTDAKCNNSPIYAEGIQTLVILLAPFAPHIGDELWQ-LLGNKN  779
            + +FNTAI++LM     + +A  ++  ++++  + +V L+APFAPH+G+ELWQ L ++ +
Sbjct  698  QMKFNTAIAQLM----VFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGE  753

Query  780  SVHTQTWPSFDPAALIADEITLVIQIMGKTRGSIQVPSQADKAELEKYARESEVAQRYIE  839
            S+    WPS+D + L+ +++ +V+QI GK ++ + V+ +  + EL+  A  +E  Q  I 
Sbjct  754  SISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIA  813

Query  840  GKEIKKVIVVPGKLVNFVL  858
            GK+I KVI VP KLVN+V+
Sbjct  814  GKDIIKVIAVPNKLVNIVI  832

699) leuS in NC_009089


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  609 bits (2300),  Expect = 3e-175, Method: Compositional matrix adjust.
 Identities = 379/855 (45%), Positives = 563/855 (66%), Gaps = 71/855 (8%)

Query  1    MSVYNFKEVESKWQKIWKDNNQYKMDTAQTEKPNYYTLEMFPYPSGK-IHMGHVRNYSIG  59
            M+ Y+   +E+KWQ +W DN+ +K +T ++ KP++Y+L+MFPYPSG  +H+GH   Y+  
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGT-DASKPKFYALDMFPYPSGAGLHVGHPEGYTAT  59

Query  60   DVVARFKKMEGYNVLHPMGWDSFGLPAENAAIKHGIHPHKWTMENIEEMKEQLNLLGISY  119
            D+++RFK+ +G NVLHPMGWD+FGLPAE+ A+  G +P   T ENI + K Q+N LG+SY
Sbjct  60   DILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSY  119

Query  120  DWDKEVATSTPEYYRFTQEIFLKFLEHGLAYKKKSYVNWCPSCETVLANEQVV-QGACER  178
            DWD+EV T+ P+YY+ TQ IF K+ E GLAY     VNW     T +ANE+V+ +G+ ER
Sbjct  120  DWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSER  179

Query  179  CKATVLKKDLEQWYFKTTEFAEELLNDLDTLDGWPEKVKTMQKNWIGKSTGADLVFDIDG  238
                V++K + QW +K T +AE LL+DL+ +D WPE +K MQ+NWIGKSTGA++ F + +
Sbjct  180  GGYPVVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKD  238

Query  239  TDKSMTVFTTRPDTTYGVTYMVLAPEHELVKELVAGTEYEADVEAFVQKMHTMTEIERTA  298
            TDK  TVFTTRPDT +G TY VLAPEH LV  + ++ + EA V  + ++    +++ RT 
Sbjct  239  TDKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEA-VADYKRQASLKSDLARTD  297

Query  299  ADVEKEGMFIGRYVINPLNGKKVPLWIANYVLVEYGTGAIMAVPAHDERDRDFAEKYNLD  358
               EK G+  G Y INP+NGK +P+WIA+YVL  YGTGAIMAVPAHDERD++FA ++NLD
Sbjct  298  LAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLD  357

Query  359  IIDVI----------TEDNKMINSEEFNGLDASEGFEGIIDKLEKEGRGKRTINYRLRDW  408
            II V+          TED   INS+ ++GLD + ++  +++ LE EG G+  + YRLRDW
Sbjct  358  IIPVLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDW  417

Query  409  LVSRQRYWGCPIPVVYCDECGIVPVKKEDLPVLLPT--DVEFTGKGESPLTTSKQFMSTT  466
            L SRQRYWG PIP++  ++    +V   +LP++LP   D+  +G GESPL+   + +  T
Sbjct  418  LFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT  477

Query  467  CPHCGKPARREVDTMDTFVDSSWYFLRYVDSNNENEPFSKELVNRWHPVDQYIGGVEHAI  526
              +  K +RRE +TM    +SSWY+LRY+D++N +     EL+++W PVD Y+GG EHA+
Sbjct  478  REDGVK-GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  527  MHLLYARWFVKAFKSMGMVDFNEPFKNLLTQGMVL-------------------------  561
            +HLLYAR   K +  +G+V  +EPF++L+ QGM+L                         
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFF  596

Query  562  ---------MDGSKMSKSKGNTVSPMDIIDEYGADTARLFVLFAAPPERDLDWSEQGVDG  612
                        +KMSKS  N V+P D++++YGADT R++ +F +P +  + WSE+G++G
Sbjct  597  HVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEG  656

Query  613  CFRFLNRVYRLVDELADVVKKDVEFGELNSQDKDMRYTIHSTLKKVTADLSEKFGFNTAI  672
              +FL+RVYRL      +  K++   E NS   D  Y  + T+K VT ++ ++  FNTAI
Sbjct  657  SRKFLDRVYRL------ITTKEI--TEENSGALDKVY--NETVKAVTEQV-DQMKFNTAI  705

Query  673  SALMELINDMYKYKELDNINEAVIKEGVQTIVTIIAPFAPHLGEELWTMIGKEGSVFD-I  731
            + LM ++N   K       ++ ++ +  + +V +IAPFAPHLGEELW  +   G  +  +
Sbjct  706  AQLMVFVNAANK-------EDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYV  758

Query  732  DWPKYDEKALVKDEIEVVVQVNGKVRGKLTVNSNISKDEMEKVALEDEKIKGLVEGKTIV  791
             WP YDE  LV +++E+VVQ++GKV++KL V  ++S++E++ VAL +EK+++ + GK I+
Sbjct  759  PWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDII  818

Query  792  KVVAVPKKLVNIVVK  806
            KV+AVP+KLVNIV+K
Sbjct  819  KVIAVPNKLVNIVIK  833

700) leuS in NC_013315


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  609 bits (2300),  Expect = 3e-175, Method: Compositional matrix adjust.
 Identities = 379/855 (45%), Positives = 563/855 (66%), Gaps = 71/855 (8%)

Query  1    MSVYNFKEVESKWQKIWKDNNQYKMDTAQTEKPNYYTLEMFPYPSGK-IHMGHVRNYSIG  59
            M+ Y+   +E+KWQ +W DN+ +K +T ++ KP++Y+L+MFPYPSG  +H+GH   Y+  
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGT-DASKPKFYALDMFPYPSGAGLHVGHPEGYTAT  59

Query  60   DVVARFKKMEGYNVLHPMGWDSFGLPAENAAIKHGIHPHKWTMENIEEMKEQLNLLGISY  119
            D+++RFK+ +G NVLHPMGWD+FGLPAE+ A+  G +P   T ENI + K Q+N LG+SY
Sbjct  60   DILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSY  119

Query  120  DWDKEVATSTPEYYRFTQEIFLKFLEHGLAYKKKSYVNWCPSCETVLANEQVV-QGACER  178
            DWD+EV T+ P+YY+ TQ IF K+ E GLAY     VNW     T +ANE+V+ +G+ ER
Sbjct  120  DWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSER  179

Query  179  CKATVLKKDLEQWYFKTTEFAEELLNDLDTLDGWPEKVKTMQKNWIGKSTGADLVFDIDG  238
                V++K + QW +K T +AE LL+DL+ +D WPE +K MQ+NWIGKSTGA++ F + +
Sbjct  180  GGYPVVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKD  238

Query  239  TDKSMTVFTTRPDTTYGVTYMVLAPEHELVKELVAGTEYEADVEAFVQKMHTMTEIERTA  298
            TDK  TVFTTRPDT +G TY VLAPEH LV  + ++ + EA V  + ++    +++ RT 
Sbjct  239  TDKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEA-VADYKRQASLKSDLARTD  297

Query  299  ADVEKEGMFIGRYVINPLNGKKVPLWIANYVLVEYGTGAIMAVPAHDERDRDFAEKYNLD  358
               EK G+  G Y INP+NGK +P+WIA+YVL  YGTGAIMAVPAHDERD++FA ++NLD
Sbjct  298  LAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLD  357

Query  359  IIDVI----------TEDNKMINSEEFNGLDASEGFEGIIDKLEKEGRGKRTINYRLRDW  408
            II V+          TED   INS+ ++GLD + ++  +++ LE EG G+  + YRLRDW
Sbjct  358  IIPVLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDW  417

Query  409  LVSRQRYWGCPIPVVYCDECGIVPVKKEDLPVLLPT--DVEFTGKGESPLTTSKQFMSTT  466
            L SRQRYWG PIP++  ++    +V   +LP++LP   D+  +G GESPL+   + +  T
Sbjct  418  LFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT  477

Query  467  CPHCGKPARREVDTMDTFVDSSWYFLRYVDSNNENEPFSKELVNRWHPVDQYIGGVEHAI  526
              +  K +RRE +TM    +SSWY+LRY+D++N +     EL+++W PVD Y+GG EHA+
Sbjct  478  REDGVK-GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  527  MHLLYARWFVKAFKSMGMVDFNEPFKNLLTQGMVL-------------------------  561
            +HLLYAR   K +  +G+V  +EPF++L+ QGM+L                         
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFF  596

Query  562  ---------MDGSKMSKSKGNTVSPMDIIDEYGADTARLFVLFAAPPERDLDWSEQGVDG  612
                        +KMSKS  N V+P D++++YGADT R++ +F +P +  + WSE+G++G
Sbjct  597  HVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEG  656

Query  613  CFRFLNRVYRLVDELADVVKKDVEFGELNSQDKDMRYTIHSTLKKVTADLSEKFGFNTAI  672
              +FL+RVYRL      +  K++   E NS   D  Y  + T+K VT ++ ++  FNTAI
Sbjct  657  SRKFLDRVYRL------ITTKEI--TEENSGALDKVY--NETVKAVTEQV-DQMKFNTAI  705

Query  673  SALMELINDMYKYKELDNINEAVIKEGVQTIVTIIAPFAPHLGEELWTMIGKEGSVFD-I  731
            + LM ++N   K       ++ ++ +  + +V +IAPFAPHLGEELW  +   G  +  +
Sbjct  706  AQLMVFVNAANK-------EDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYV  758

Query  732  DWPKYDEKALVKDEIEVVVQVNGKVRGKLTVNSNISKDEMEKVALEDEKIKGLVEGKTIV  791
             WP YDE  LV +++E+VVQ++GKV++KL V  ++S++E++ VAL +EK+++ + GK I+
Sbjct  759  PWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDII  818

Query  792  KVVAVPKKLVNIVVK  806
            KV+AVP+KLVNIV+K
Sbjct  819  KVIAVPNKLVNIVIK  833

701) leuS in NC_013316


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  609 bits (2300),  Expect = 3e-175, Method: Compositional matrix adjust.
 Identities = 379/855 (45%), Positives = 563/855 (66%), Gaps = 71/855 (8%)

Query  1    MSVYNFKEVESKWQKIWKDNNQYKMDTAQTEKPNYYTLEMFPYPSGK-IHMGHVRNYSIG  59
            M+ Y+   +E+KWQ +W DN+ +K +T ++ KP++Y+L+MFPYPSG  +H+GH   Y+  
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGT-DASKPKFYALDMFPYPSGAGLHVGHPEGYTAT  59

Query  60   DVVARFKKMEGYNVLHPMGWDSFGLPAENAAIKHGIHPHKWTMENIEEMKEQLNLLGISY  119
            D+++RFK+ +G NVLHPMGWD+FGLPAE+ A+  G +P   T ENI + K Q+N LG+SY
Sbjct  60   DILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSY  119

Query  120  DWDKEVATSTPEYYRFTQEIFLKFLEHGLAYKKKSYVNWCPSCETVLANEQVV-QGACER  178
            DWD+EV T+ P+YY+ TQ IF K+ E GLAY     VNW     T +ANE+V+ +G+ ER
Sbjct  120  DWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSER  179

Query  179  CKATVLKKDLEQWYFKTTEFAEELLNDLDTLDGWPEKVKTMQKNWIGKSTGADLVFDIDG  238
                V++K + QW +K T +AE LL+DL+ +D WPE +K MQ+NWIGKSTGA++ F + +
Sbjct  180  GGYPVVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKD  238

Query  239  TDKSMTVFTTRPDTTYGVTYMVLAPEHELVKELVAGTEYEADVEAFVQKMHTMTEIERTA  298
            TDK  TVFTTRPDT +G TY VLAPEH LV  + ++ + EA V  + ++    +++ RT 
Sbjct  239  TDKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEA-VADYKRQASLKSDLARTD  297

Query  299  ADVEKEGMFIGRYVINPLNGKKVPLWIANYVLVEYGTGAIMAVPAHDERDRDFAEKYNLD  358
               EK G+  G Y INP+NGK +P+WIA+YVL  YGTGAIMAVPAHDERD++FA ++NLD
Sbjct  298  LAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLD  357

Query  359  IIDVI----------TEDNKMINSEEFNGLDASEGFEGIIDKLEKEGRGKRTINYRLRDW  408
            II V+          TED   INS+ ++GLD + ++  +++ LE EG G+  + YRLRDW
Sbjct  358  IIPVLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDW  417

Query  409  LVSRQRYWGCPIPVVYCDECGIVPVKKEDLPVLLPT--DVEFTGKGESPLTTSKQFMSTT  466
            L SRQRYWG PIP++  ++    +V   +LP++LP   D+  +G GESPL+   + +  T
Sbjct  418  LFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT  477

Query  467  CPHCGKPARREVDTMDTFVDSSWYFLRYVDSNNENEPFSKELVNRWHPVDQYIGGVEHAI  526
              +  K +RRE +TM    +SSWY+LRY+D++N +     EL+++W PVD Y+GG EHA+
Sbjct  478  REDGVK-GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  527  MHLLYARWFVKAFKSMGMVDFNEPFKNLLTQGMVL-------------------------  561
            +HLLYAR   K +  +G+V  +EPF++L+ QGM+L                         
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFF  596

Query  562  ---------MDGSKMSKSKGNTVSPMDIIDEYGADTARLFVLFAAPPERDLDWSEQGVDG  612
                        +KMSKS  N V+P D++++YGADT R++ +F +P +  + WSE+G++G
Sbjct  597  HVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEG  656

Query  613  CFRFLNRVYRLVDELADVVKKDVEFGELNSQDKDMRYTIHSTLKKVTADLSEKFGFNTAI  672
              +FL+RVYRL      +  K++   E NS   D  Y  + T+K VT ++ ++  FNTAI
Sbjct  657  SRKFLDRVYRL------ITTKEI--TEENSGALDKVY--NETVKAVTEQV-DQMKFNTAI  705

Query  673  SALMELINDMYKYKELDNINEAVIKEGVQTIVTIIAPFAPHLGEELWTMIGKEGSVFD-I  731
            + LM ++N   K       ++ ++ +  + +V +IAPFAPHLGEELW  +   G  +  +
Sbjct  706  AQLMVFVNAANK-------EDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYV  758

Query  732  DWPKYDEKALVKDEIEVVVQVNGKVRGKLTVNSNISKDEMEKVALEDEKIKGLVEGKTIV  791
             WP YDE  LV +++E+VVQ++GKV++KL V  ++S++E++ VAL +EK+++ + GK I+
Sbjct  759  PWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDII  818

Query  792  KVVAVPKKLVNIVVK  806
            KV+AVP+KLVNIV+K
Sbjct  819  KVIAVPNKLVNIVIK  833

702) ES1_07210 in NC_021043


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  609 bits (2300),  Expect = 3e-175, Method: Compositional matrix adjust.
 Identities = 373/832 (45%), Positives = 548/832 (66%), Gaps = 42/832 (5%)

Query  6    YDFSAIESKWQKYWDEHQTFKAENGSTKPKFYALVEFPYPSGAGMHVGHIKAYSGLEVVS  65
            YD +AIE+KWQ +W +++TFK+  +++KPKFYAL  FPYPSGAG+HVGH  +Y++ +++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  66   RKRRLQGYNVLFPIGFDAYGLPTENTAIKTGVHPRKVTDNNIVKFTNQLKRVGFSFDWSR  125
            R +R QG NVL P+G DA+GLP+E+ A+ TG +P   T +NI +F  Q++ +GFS+DW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  126  VIDTTEERYYKWTQWIFLKMFEHGLVFRDKTLVNYCPSCKVVLSNEDS-QGGHCDICHSE  184
             ++TT+  YYKWTQWIF K++E GL +     VN        ++NE+   +G  +     
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  185  IVQKTKEVWYLRITEYADKLLQGLETVDYLPNVKLQQENWIGKSTGAFVNFSIKENGEKL  244
            +V+K    W L+IT YA++LL++LE VD   ++K  Q NWIGKSTGA V F +K+ +  +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  245  RIYTTRPDTLYGVTFMVIAPEHPIIEKYRDSIKNIADLDAYKAECSKKSEFERTQLVKDK  304
             ++TTRPDTL+G T+ V+APEH++++    S  +   +  YK + S KS++ RT+L K+K
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTS-DQAEAVADYKRQASLKSDLARTDLAKEK  302

Query  305  TGVKIDGLTGVNPVTGKEIPIYISDYVMMGYGTGAIMAVPAHDTRDYEFAKKFGIDIIEV  364
            TGV  ++  ++NPV GKE+P+ I+DYV+ +YGTGAIMAVPAHD RD EFAK+F +DII V
Sbjct  303  TGVWTGSY-AINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  365  IKGGDISKEAYTGDGEMVNSGELNGITNKKDAIEKMLGVLAKLGCGEKGVQYKMKDWAFN  424
            + GG++   A+T DG  +NS+ L+G+ +K  AI KM+  L   G G+  V Y+++DW F+
Sbjct  362  LEGGNVEEAAFTEDGLHINSDFLDGL-DKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  425  RQRYWGEPIPIVHCPDCGIvpvpyeelplelppveNFQPGQDGESPLAKIDSFVHCKCPK  484
            RQRYWGEPIPI+H  D    +VP  ELPL LP   +++P+  GESPLA++   ++     
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  485  CGKDARRETDTMPQWAGSSWYFLRYCDPNNDKEFASQEALKYWLPVDWYNGGMEHVTRHM  544
              K +RRET+TMPQWAGSSWY+LRY DP+N   +A +E LK WLPVD Y GG EH   H+
Sbjct  481  GVK-GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHL  539

Query  545  IYSRFWHKFLYDIGEVPTPEPYAKRTAQGLILGP--------------------------  578
            +Y+RFWHK LYD+G VPT EP+ K   QG+ILG                           
Sbjct  540  LYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVE  599

Query  579  -------DGEKMSKSRGNVIDPNDVVDVYGADVLRVYVLFMGDYEQAAPWNDSSMKGCKR  631
                      KMSKS  NV++P+DVV+ YGAD LRVY +FMG  + + +W++ ++ G ++
Sbjct  600  TGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRK  659

Query  632  FLDRVWNLQNMLVRGDEYSDELRTSMHKTIKKVSEDIEKMRFNTAIAAMMSLINEITANG  691
            FLDRV  L       +E S+ L    + T+K V+E++++M+FNTAIA +M ++N    ++
Sbjct  660  FLDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKED  719

Query  692  KINDAEMKSLLILLNPFAPHITEEMYNSLGYG--ILNEAQWVTYDEALCVDSTVEIVVQL  749
            K+     K+++ L+ PFAPH+ EE+ ++L  +   ++   W +YDE+  V++ VEIVVQ+
Sbjct  720  KLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQI  779

Query  750  CGKIKARINVPTAADKDEL--LKMAKEAIAQSLEGKTIRKEIVVPGKLVNIV  799
             GK+KA++ V+    ++EL  + +A+E +   + GK I K I VP KLVNIV
Sbjct  780  KGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIV  831

703) Cal6303_4910 in NC_019751


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  609 bits (2299),  Expect = 4e-175, Method: Compositional matrix adjust.
 Identities = 387/862 (45%), Positives = 584/862 (68%), Gaps = 40/862 (4%)

Query  5    YNPADIEEKWQKTWAELGLDKTSSDSSKPKFYALSMFPYPSGS-LHMGHVRNYTITDAIA  63
            Y+ + IE KWQ  WA+    KT++D+SKPKFYAL MFPYPSG+ LH+GH   YT TD ++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RLKRMQGYRVLHPMGWDAFGLPAENAAIDRNVPPSQWTYQNIQHMRSQLQKLGLFIDWDN  123
            R+KR QG  VLHPMGWDAFGLPAE+ A+D    P++ T +NI + + Q++ LG+  DWD 
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCSPDYYRWTQWIFLQFFQAGLAYQKEAAVNWDPIDQTVIANEQVI-DGRSWRSGAI  182
            E+ T  P+YY+WTQWIF ++++ GLAY+ E +VNW     T IANE+V+ DG S R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKLLRQWFLKITAYAEELLQDLDKLPGWPEKVRKLQANWIGKSTGAYLEFPVVGMDEK  242
            V RK +RQW LKITAYAE LL+DL+ + +WPE ++ +Q NWIGKSTGA + F V + D  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  IGVYTTRPDTVYGVSYVVLAPEHPLTTKVTTASQADAVAEFAKEVGNQSELERTAEDKPK  302
            + V+TTRPDT++G +Y VLAPEH+L   +TT+ QA+AVA++ ++ + +S+L RT   K K
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEK  302

Query  303  RGIPTGGMAINPFTGEEIPILIADYVLYEYGTGAVMGVPAHDVRDFKFAKNYNLPIKFVI  362
             G+ TG+ AINP  G E+P+ IADYVL  YGTGA+M+VPAHD RD  FAK++NL I  V+
Sbjct  303  TGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL  362

Query  363  VPNDNKEAHNQDAAYTDAGILVNSQQFDDMDSIEAKKAIVKYAESQGFGKERVQFRLRDW  422
                   ++ ++AA+T+ G+ +NS+ +D++D   A   +V   E++G G+E V +RLRDW
Sbjct  363  -----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDW  417

Query  423  LISRQRYWGAPIPIIHCPECGAVPVPDADLPVQLP--DNIELTGRGGSPLANLESWVNVP  480
            L+SRQRYWG PIPIIH  +  + +VP+++LP+ LP   +I  +G G SPLAN+  W++V 
Sbjct  418  LFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT  477

Query  481  CPSCGTPAKRETDTMDTFIDSSWYYLRFTDANNSEEIFTKEKVNSWMPVDQYVGGVEHAI  540
                G  ++RET+TM    +SSWYYLR+ D++N+E +   E ++ W+PVD YVGG EHA+
Sbjct  478  RED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  541  LHLLYSRFFTKVLRDHACAPNGERGLLQFDEPFKQLLTQGMVQGLTYMNPKKSDKDKWVP  600
            LHLLY+RF  KVL D +  P          EPF++L+ QGM+ G +Y +++ +     V+
Sbjct  537  LHLLYARFWHKVLYDLGVVPT--------KEPFQKLFNQGMILGTSYRDSRGAL----VA  584

Query  601  TNLVNAADPR--DPQTGDPLQLVYATMSKSKGNGVAPEDIIAKYGVDTARMFILFKAPPE  658
            T+ V+  D    + +TG+ L+   A MSKS  N V P+D++ +YG DT R++ +F +P +
Sbjct  585  TDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLD  644

Query  659  KDLEWDEADVEGQFRFLNRVWRLVTEYIAVDSKSNKLQESKAEKDLRRAIHIAIKEISED  718
              + W E ++EG  +FL+RV RL+T        ++ + E ++   L +  + ++K ++E+
Sbjct  645  ASIAWSEEGLEGSRKFLDRVYRLIT--------TKEITEENSG-ALDKVYNETVKAVTEQ  695

Query  719  VNEGYQLNTAISELMKLSNALTDADCKTSPIYSEGIRTLLLLLAPFAPHIAEELWH-LLG  777
            V++  ++NTAI++LM     + +A  K   ++S+  + ++ L+APFAPH++EELW+ L +
Sbjct  696  VDQM-KFNTAIAQLM----VFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTA  750

Query  778  NKESVHTQAWLNHDPEALIADEITLVVQVNGKKRADIPVPAKADKAELEKYALASEAVQR  837
            + ES+   +W + D   L+ +++ +VVQ++GK +A + V+    + EL+  ALA+E VQ 
Sbjct  751  SGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQA  810

Query  838  HLEGKEIKKVIVVPGKLVNFVV  859
            ++ GK+I KVI VP KLVN+V+
Sbjct  811  EIAGKDIIKVIAVPNKLVNIVI  832

704) leuS in NC_007503


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  608 bits (2298),  Expect = 4e-175, Method: Compositional matrix adjust.
 Identities = 396/854 (47%), Positives = 574/854 (68%), Gaps = 64/854 (7%)

Query  5    YDFKAIEAKWQKKWEELKLYEVDDFSEKPKYYCLEMFPYPSGK-LHMGHVRNYSIGDVVA  63
            YD  AIE+KWQ  W +   +  +  + KPK+Y L+MFPYPSG  LH+GH   Y+  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYKRMRGYAVLHPMGWDAFGLPAENAAIKHGNVHPADWTWDNIANMRRQLKELGISYDWR  123
            R+KR +G  VLHPMGWDAFGLPAE+ A+  GN +PA+ T +NIAN +RQ++ LG+SYDW 
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGN-DPAEFTAENIANFKRQINALGFSYDWD  122

Query  124  REIATCHPEYYRWTQWLFLQFYKKGLAYKKKAPVNWCPGCQTVLANEQVI-DGECERCHS  182
            RE+ T +P+YY+WTQW+F ++Y KGLAY    PVNW     T +ANE+V+ DG  ER   
Sbjct  123  REVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGY  182

Query  183  RVEKKELEQWFFKITAYAERLLQDIKKLTGWPEKVKIMQENWIGRSEGAEITFKIKGHEE  242
             V +K + QW +KITAYAERLL+D+  + +WPE +K MQ NWIG+S GA++TFK+K+ + 
Sbjct  183  PVVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDK  241

Query  243  TISVFTTRPDTIFGVTYMVLAPEHPLVEKISRGTQYEKDVLEFKRKMMYLSEIERTAETA  302
             ++VFTTRPDT+FG TY VLAPEH+LV+ I+ + Q    V ++KR+    S++ RT  + 
Sbjct  242  DFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQ-AEAVADYKRQASLKSDLARTDLAK  300

Query  303  EKEGVFTGAYAINPFTGEEIPILLANYVLVEYGTGAVMGVPAHDQRDFLFAKKYNLPIKV  362
            EK GV TG+YAINP  G E+P+ +A+YVL  YGTGA+M+VPAHD+RD  FAK++NL I  
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  363  VITPPGQELKAEELTEAYTGEGILVNSGEFTGLANKEAIRIITQEAEKRGFGKYRVNYRL  422
            V+     E        A+T +G+ +NS+ + GL +  AI  + +  E  G G+  V YRL
Sbjct  361  VLEGGNVE------EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRL  414

Query  423  RDWLISRQRYWGAPIPVLYCEKCGIVPVPEDQLPVVLPYNVEFRP--TGESPLKYVPEFL  480
            RDWL+SRQRYWG PIP++  E     +VPE +LP+VLP   ++RP  TGESPL  V + L
Sbjct  415  RDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWL  474

Query  481  NATCPECGGPATRETDTMDTFICSSWYYYRYTSPRDKQQPWSKEKVERWLPVDQYIGGVE  540
            + T  + G  + RET+TM     SSWYY RY  P++ ++    E + +WLPVD Y+GG E
Sbjct  475  EVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAE  533

Query  541  HAILHLLYSRFFTKVLYDLGLVHVDEPFTNLLTQGMVL-------------------KDG  581
            HA+LHLLY+RF  KVLYDLG+V   EPF +L+ QGM+L                   +DG
Sbjct  534  HAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDG  593

Query  582  ---------------AKMSKSKGNVVSPEEIVEKYGADTARLFILFAAPPERDLEWSDQG  626
                           AKMSKS  NVV+P+++VE+YGADT R++ +F +P +  + WS++G
Sbjct  594  SFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEG  653

Query  627  VEGSFRFLNRVWRLIYQTKDRISDELREFSAKDKELNRLLHATIKKVTEDIEERFNFNTA  686
            +EGS +FL+RV RLI  T   I++E      +   L+++ + T+K VTE++++  +FNTA
Sbjct  654  LEGSRKFLDRVYRLI--TTKEITEE------NSGALDKVYNETVKAVTEQVDQ-MKFNTA  704

Query  687  ISAIMELVNGLYQYKEGEINPGLLKEALNKLVILLAPFAPHIAEELWEAL-GNKQSVHLE  745
            I+ +M +VN+      ++ +  L+ +  + +V L+APFAPH++EELW+AL ++ +S+   
Sbjct  705  IAQLMVFVNA------ANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYV  758

Query  746  KWPEYDEEALITEEVEIVIQVNGKVKDRVMVPRNAAEDELKEIALNTPKIKELTADkkii  805
             WP YDE  L+ ++VEIV+Q++GKVK +++V+++ + +EL+E+AL   K++   A+K II
Sbjct  759  PWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDII  818

Query  806  kviivPEKLINIVV  819
            KVI VP+KL+NIV+
Sbjct  819  KVIAVPNKLVNIVI  832

705) EUS_23420 in NC_021011


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  608 bits (2298),  Expect = 4e-175, Method: Compositional matrix adjust.
 Identities = 373/832 (45%), Positives = 548/832 (66%), Gaps = 42/832 (5%)

Query  6    YDFSAIESKWQKYWDEHQTFKAENGSTKPKFYALVEFPYPSGAGMHVGHIKAYSGLEVVS  65
            YD +AIE+KWQ +W +++TFK+  +++KPKFYAL  FPYPSGAG+HVGH  +Y++ +++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  66   RKRRLQGYNVLFPIGFDAYGLPTENTAIKTGVHPRKVTDNNIVKFTSQLKRVGFSFDWSR  125
            R +R QG NVL P+G DA+GLP+E+ A+ TG +P   T +NI +F  Q++ +GFS+DW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  126  VIDTTEERYYKWTQWIFLKMFEHGLVFRDKTLVNYCPSCKVVLSNEDS-QGGHCDICHSE  184
             ++TT+  YYKWTQWIF K++E GL +     VN        ++NE+   +G  +     
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  185  IVQKTKEVWYLRITEYADKLLQGLETVDYLPNVKLQQENWIGKSTGAFVNFSIKENGEKL  244
            +V+K    W L+IT YA++LL++LE VD   ++K  Q NWIGKSTGA V F +K+ +  +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  245  RIYTTRPDTLYGVTFMVIAPEHPIIEKYRDSIKNIADLDAYKAECSKKSEFERTQLVKDK  304
             ++TTRPDTL+G T+ V+APEH++++    S  +   +  YK + S KS++ RT+L K+K
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTS-DQAEAVADYKRQASLKSDLARTDLAKEK  302

Query  305  TGVKIDGLTGVNPVTGKEIPIYISDYVMMGYGTGAIMAVPAHDTRDYEFAKKFGIDIIEV  364
            TGV  ++  ++NPV GKE+P+ I+DYV+ +YGTGAIMAVPAHD RD EFAK+F +DII V
Sbjct  303  TGVWTGSY-AINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  365  IKGGDISKEAYTGDGEMVNSGELNGITNKKDAIEKMLGVLTKLGCGEKGVQYKMKDWAFN  424
            + GG++   A+T DG  +NS+ L+G+ +K  AI KM+  L   G G+  V Y+++DW F+
Sbjct  362  LEGGNVEEAAFTEDGLHINSDFLDGL-DKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  425  RQRYWGEPIPIVHCPDCGIvpvpyeelplelppveNFQPGQDGESPLAKIDSFVHCKCPK  484
            RQRYWGEPIPI+H  D    +VP  ELPL LP   +++P+  GESPLA++   ++     
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  485  CGKDARRETDTMPQWAGSSWYFLRYCDPNNDKEFASQEALKYWLPVDWYNGGMEHVTRHM  544
              K +RRET+TMPQWAGSSWY+LRY DP+N   +A +E LK WLPVD Y GG EH   H+
Sbjct  481  GVK-GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHL  539

Query  545  IYSRFWHKFLYDIGEVPTPEPYAKRTAQGLILGP--------------------------  578
            +Y+RFWHK LYD+G VPT EP+ K   QG+ILG                           
Sbjct  540  LYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVE  599

Query  579  -------DGEKMSKSRGNVIDPNDVVDVYGADVLRVYVLFMGDYEQAAPWNDSSMKGCKR  631
                      KMSKS  NV++P+DVV+ YGAD LRVY +FMG  + + +W++ ++ G ++
Sbjct  600  TGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRK  659

Query  632  FLDRVWNLQNMLVRGDEYSDELRTSMHKTIKKVSEDIEKMRFNTAIAAMMSLINEITANG  691
            FLDRV  L       +E S+ L    + T+K V+E++++M+FNTAIA +M ++N    ++
Sbjct  660  FLDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKED  719

Query  692  KINDAEMKSLLILLNPFAPHITEEMYNSLGYG--ILNEAQWVTYDEALCVDSTVEIVVQL  749
            K+     K+++ L+ PFAPH+ EE+ ++L  +   ++   W +YDE+  V++ VEIVVQ+
Sbjct  720  KLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQI  779

Query  750  CGKIKARINVPTAADKDEL--LKMAKEAIAQSLEGKTIRKEIVVPGKLVNIV  799
             GK+KA++ V+    ++EL  + +A+E +   + GK I K I VP KLVNIV
Sbjct  780  KGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIV  831

706) Desru_1058 in NC_015589


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  608 bits (2298),  Expect = 4e-175, Method: Compositional matrix adjust.
 Identities = 376/863 (44%), Positives = 579/863 (68%), Gaps = 74/863 (8%)

Query  5    YDFKEIEKKWQQYWEQENIYQVPDDSERPKYYCLEMFPYPSGK-LHMGHVRNYSIGDVVA  63
            YD   IE KWQ +W +++ ++   D+ +PK+Y L+MFPYPSG  LH+GH   Y+  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RFKTMQGFDVLHPMGWDAFGLPAENAAIKHGIPPATWTWDNIEQMKAQLKQLGLSYDWRR  123
            RFK  QG +VLHPMGWDAFGLPAE+ A+  G  PA  T +NI + K Q++ LG+SYDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVATCHPEYYRWGQWLFLQLYKQGLCYKKHARVNWCPACATVLANEQVV-EGSCERCSAT  182
            EV T +P+YY+W QW+F +LY +GL Y  +  VNW    +T +ANE+V+ +G+ ER +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VEQKELDQWFFRITDYSQRLLDDLKKLEGWPDKVKIMQENWIGRSEGAELAFKVDGTDDE  242
            V +K + QW ++IT Y++RLL+DL  ++ WP+ +K MQ NWIG+S GA+++FKV +TD +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  IKVFTTRPDTVYGVTYMVLAAEHPLVAKLSAGTPQEAKVAEFVNRVAKQTELART--STE  300
            + VFTTRPDT++G TY VLA+EH+LV  ++++   EA VA++  + + +++LART  + E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEA-VADYKRQASLKSDLARTDLAKE  301

Query  301  KEGVFTGAYCINPFNGEKVPILTANYVLYHYGTGAVMGVPAHDERDFEFARKYDLPIKVV  360
            K GV TG+Y INP NG  +P+  A+YVL  YGTGA+M+VPAHDERD EFA++++L I  V
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  361  ITPSKEKALHPDQMTEAYVSAGFMIHSGPFDGTPNQQGIRKVIEYAEQKGIGQGLVNFRL  420
            +  ++           A+   G+ I+S+ +DG  +  +I K++E  E  G+G+  V +RL
Sbjct  362  LEGGNVEE-------AAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRL  414

Query  421  RDWLISRQRYWGTPIPIIYCEQCGALPVPEDQLPVLLPTEVAFKP--TGESPLKGDADFV  478
            RDWL+SRQRYWG PIPII  E+  + +VPE +LP++LP    ++P  TGESPL   +D +
Sbjct  415  RDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWL  474

Query  479  QTTCPHCGGKARRETDTMDTFVDSSWYYIRYTSARDAQEAWNKAKAKGWMPVDQYIGGVE  538
            + T  + G K+RRET+TM    +SSWYY+RY  +++++   +    K W+PVD Y+GG E
Sbjct  475  EVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAE  533

Query  539  HAILHLLYSRFFTKVFYDLDLLDVQEPFENLLTQGMVL-------------------KDG  579
            HA+LHLLY+RF  KV+YDL+++  +EPF++L+ QGM+L                   +DG
Sbjct  534  HAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDG  593

Query  580  ---------------AKMSKSKGNVVSPEDIVARYGADTARLFILFAAPPERDLEWSDRG  624
                           AKMSKS  NVV+P+D+V +YGADT R++ +F +P +  + WS+ G
Sbjct  594  SFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEG  653

Query  625  VEGSHRFLNRVWRLVYSVKDQVIAAPPVRAENYIGVHKEMRRLTHYAIKKVTEDISGRFN  684
            +EGS++FL+RV RL        I++  +  EN       + ++ + ++K VTE++ ++ +
Sbjct  654  LEGSRKFLDRVYRL--------ITTKEITEEN----SGALDKVYNETVKAVTEQV-DQMK  700

Query  685  FNTAISAIMELVNGAYTYRDKVAEVERDPAVLAEAINSMIILLAPFAPHVAEELWQETGH  744
            FNTAI+ +M +VN+A          +++  ++++  ++ + L+APFAPH++EELWQ    
Sbjct  701  FNTAIAQLMVFVNAA----------NKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTA  750

Query  745  RG-SVHKEPWPAYDPAALveeeveIAIQINGKIRDRMNISANLKPAEMQEILLQKESIQA  803
             G S+   PWP+YD + LVE++VEI +QI+GK++ ++ ++ +L   E+QE+ L +E +QA
Sbjct  751  SGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQA  810

Query  804  LIAGKQIVKVIPVPGKLLNIVVR  826
             IAGK+I+KVI+VP KL+NIV++
Sbjct  811  EIAGKDIIKVIAVPNKLVNIVIK  833

707) CCALI_00923 in NC_021487


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  608 bits (2297),  Expect = 5e-175, Method: Compositional matrix adjust.
 Identities = 386/877 (45%), Positives = 567/877 (65%), Gaps = 52/877 (5%)

Query  11   YDFRAIERKWQQRWEEAQLFRVEIRHDRPKFYGLDMFPYPSGAGLSVGHCRNYIPLDVAC  70
            YD  AIE KWQ  W + + F+      +PKFY+LDMFPYPSGAGL VGH   Y + D+  
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  71   RLKVLQGYNVLHPMGWDAFGQPAENEAIKRGRNPKEMVLEYAANYRRQLKLVGISYDWSR  130
            R+K  QG NVLHPMGWDAFG PAE+ A+  G +P E   E  AN++RQ++ +G+SYDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  131  EINSSSPEYYRWTQWIFLQLYKNNLAYRANAPVNWCPQCKTVLANEEVV-NGRCWRCGSL  189
            E+N++ P+YY+WTQWIF +LY + LAY A+ PVNW  +  T +ANEEV+ +G   R G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  190  VEKRQVPQWFFRITAYAEKLLEGLQRVNWPEGVKALQANWIGRSEGAEIVFPVDGHTETI  249
            V ++ + QW ++ITAYAE+LLE+L+ V+WPE++K +Q NWIG+S GA++ F V +    +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  250  AVFTTRPDTLWGATFMVLAPEHPLVDKLTTPEYRAQVEAYKERAQRTSDIDRQNVERAKT  309
            +VFTTRPDTL GAT+ VLAPEH+LVD +TT++    V  YK +A   SD+ R ++ + KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  310  GVFIGSYCINPVTGERIPIYIADYVLMGYGTGAIMAVPAHDQRDFEFAKRYGLPIRLVYQ  369
            GV  GSY INPV G  +P+ IADYVL +YGTGAIMAVPAHD+RD EFAK++ L I     
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDI-----  358

Query  370  ISPEQTAESLTEAVPEGGTMVNTGLFDGLPNNKETISRVISYLEEKGIGRGVVTYRLRDW  429
            I+  + ++    A  E+G  +N++++DGL ++  +I++++  LE  G+G   VTYRLRDW
Sbjct  359  IPVLEGGNVEEAAFTEDGLHINSDFLDGL-DKASAIAKMVEWLEAEGVGNENVTYRLRDW  417

Query  430  LISRQRYWGAPIPIIHCPTCGEVPVPEDQLPVLLPPVERYEPTGTGESPLAGIPEFVHTT  489
            L+SRQRYWG PIPIIH       +VPE +LP++LP      P+GTGESPLA + + ++ T
Sbjct  418  LFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT  477

Query  490  CPRCNG-PARRETDTMGGSACSSWYYLRFADPHNNREAFSQEAVRYWLPVDLYAGGAEHA  548
              R +G  +RRET+TM   A SSWYYLR+ DPHN      +E ++ WLPVD+Y GGAEHA
Sbjct  478  --REDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  549  VGHLLYARFWTKALHDMGYLHFDEPFLTYRNQGAVLAYTPgrevgkeengeeeelgadep  608
            V HLLYARFW K L D+G +   EPF    NQG +L+       +        +      
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILG---TSYRDSRGALVATDKVEKRD  592

Query  609  ieNWKVLKPEERETIPPEKWVWRWVRMSKSKGNVVTPDEMAERYGSDSLRLFLLFVAPYE  668
                 V   EE E  P+        +MSKS  NVV PD++ E+YG+D+LR++ +F++P +
Sbjct  593  GSFFHVETGEELEQAPA--------KMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLD  644

Query  669  ENVQWSDKGMEGAHRFVNRIWRIWHELRPHYRADWREHMPPLSELSPTDR-ALRRKLHQT  727
             ++ WS+ G+EG+++F++R+          YR      +    E++  +  AL +  ++T
Sbjct  645  ASIAWSEEGLEGSRKFLDRV----------YR------LITTKEITEENSGALDKVYNET  688

Query  728  IRKVETDIEHFRFNTAVAALMEYTNELSAYRNAVANREPTPVQACLISEALETLPILFSP  787
            ++ V  ++++ +FNTA+A LM + N             ++  +  L+S+    +  L++P
Sbjct  689  VKAVTEQVDQMKFNTAIAQLMVFVN-------------AANKEDKLFSDYAKGFVQLIAP  735

Query  788  ITPHLADEWWERLGKEGFTFN-QCWPKYDPEVAKEEEITVVVQINGKIRDKLQVSPETPS  846
            ++PHL++E W+ L   G +++   WP YD     E+++ +VVQI+GK++ KL V+ + + 
Sbjct  736  FAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSR  795

Query  847  DELERLALASGRVQTELQGRVPQKIIVVPQKLVNIVV  883
            +EL+ +ALA+ +VQ+E+ G+   K+I VP+KLVNIV+
Sbjct  796  EELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

708) leuS in NC_007604


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  607 bits (2293),  Expect = 1e-174, Method: Compositional matrix adjust.
 Identities = 390/849 (46%), Positives = 568/849 (67%), Gaps = 27/849 (3%)

Query  21   YDPQAIETKWQQSWAAAQLDRTPEADDRPKFYALSMFPYPSG-NLHMGHVRNYTITDAIA  79
            YD  AIE KWQ  WA  +  +T     +PKFYAL MFPYPSG  LH+GH   YT TD ++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  80   RVKRRQGFRVLHPMGWDAFGLPAENAAIDRGVQPADWTYQNVAQMREQLKQLGLSYDWDR  139
            R KR QG  VLHPMGWDAFGLPAE+ A+D G +PA+ T +N+A+ + Q++ LG+SYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  140  EVTTCSPDYYRWTQWLFLQFFEAGLAYQKEATVNWDPIDQTVLANEQVDSEGRSWRSGAK  199
            EV T  P+YY+WTQW+F +++E GLAY+ E  VNW     T +ANE+V ++G S R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  200  VERRQLKQWFLKITDYAEELLQDLDQLTGWPERVRLMQANWIGKSTGAYLEFPIVNSSDR  259
            V R+ ++QW LKIT YAE LL+DL+++ +WPE ++ MQ NWIGKSTGA + F + ++   
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  260  VKVFTTRPDTVYGVSYVVLAPEHPLVTQVTTPEQQTAVAAFAAEVSQTSELERTAEDRPK  319
              VFTTRPDT++G +Y VLAPEH+LV  +TT++Q  AVA +  + S  S+L RT   + K
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEK  302

Query  320  RGVPTGGFVTNPFTGQAVPIWIADYVLVEYGTGAVMGVPAHDSRDFAFAQRYGLPVQPVI  379
             GV TG++  NP  G+ +P+WIADYVL  YGTGA+M+VPAHD RD  FA+++ L + PV+
Sbjct  303  TGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL  362

Query  380  QPTEGAIAEPWPAPFTEAGVMVNSGQFDGLSSTeakakiiafaeeQGWGQAHVQYRLRDW  439
            +   G + E   A+FTE G+ +NS+ +DGL  + A AK++   E +G G+ +V YRLRDW
Sbjct  363  E--GGNVEE---AAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDW  417

Query  440  LISRQRYWGCPIPIVH--CPDCGPVAAADLPVQLP--DSVQFSGRGPSPLAQLEDWVTTT  495
            L+SRQRYWG PIPI+H       +V+ ++LP+ LP    ++ SG G SPLA++ DW+  T
Sbjct  418  LFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT  477

Query  496  CPSCGKPARRETDTMDTFMCSSWYYLRYSDASNPEIAFTKDKVNDWLPVDQYVGGIEHAI  555
                 K +RRET+TM     SSWYYLRY D+ N E     + +++WLPVD YVGG EHA+
Sbjct  478  REDGVK-GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  556  LHLLYSRFFTKVLRDRGLLSFDEPFKRLLTQGMVQGLTYKNPKTGKYVPSDRISDPSQP-  614
            LHLLY+RF  KVL D G+++  EPF++L+ QGM+ G +Y++++ G  V++D++     + 
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSR-GALVATDKVEKRDGSF  595

Query  615  VDPDTGDRLEVFFEKMSKSKYNGVDPARVLDRYGADTARMFILFKAPPEKDLEWDDADVE  674
             + +TG+ LE    KMSKS  N V+P  V+++YGADT R++ +F +P +  + W + ++E
Sbjct  596  FHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLE  655

Query  675  GQFRFLNRVWRLVQTASQVeattaaddkaekdLRRAVHTAIQAVTEDLEEDYQLNTAIAE  734
            G  +FL+RV RL+ T           +     L +  + +++AVTE++++  ++NTAIA+
Sbjct  656  GSRKFLDRVYRLITTKE-------ITEENSGALDKVYNETVKAVTEQVDQM-KFNTAIAQ  707

Query  735  LMKLTNALNDAPMPGSPAYLEGVQTLVLLLAPFAPHIAEELWQQL-GGERSVHLEGWPVL  793
            LM + NA N         + +  + +V L+APFAPH++EELWQ L ++  S+    WP  
Sbjct  708  LMVFVNAANKE----DKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSY  763

Query  794  DESALIVDEIPLVIQIMGKTRGTITVPASADRDQLQQLAENSEIAQRWLDGQTIRKVIVV  853
            DES L+ +++ +V+QI GK ++ + V+    R++LQ++A  +E  Q  + G+ I KVI V
Sbjct  764  DESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAV  823

Query  854  PGKLVNFVI  862
            P KLVN+VI
Sbjct  824  PNKLVNIVI  832

709) leuS in NC_018623


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  607 bits (2293),  Expect = 7e-175, Method: Compositional matrix adjust.
 Identities = 353/661 (54%), Positives = 494/661 (75%), Gaps = 14/661 (2%)

Query  3    YDPSLIEKKWQQFWKEHKSFKADETADKPKYYVLDMFPYPSGAGLHVGHLIGYTATDIVA  62
            YD + IE KWQ FW ++ +FK++  A KPK+Y LDMFPYPSGAGLHVGH  GYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRAKGFSVLHPMGWDSFGLPAEQYAVRTGTHPRETTKKNIENFRKQLSAMGFSYDEGR  122
            R+KRA+G +VLHPMGWD+FGLPAEQYA+ TG +P E T  NI NF++Q++A+GFSYD +R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EFATSDPDYYRWTQKLFLFLYEKGLAYMADMAVNYCEELGTVLANEEV-ANGLSLEGGYP  181
            E  T+DP+YY+WTQ +F  LYEKGLAY A+++VN  EELGT +ANEEV ++G S  GGYP
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VERRMLRQWILRITAYSDQLLQGLEDLDWPENVKQLQRNWIGKSEGALVRFEV-DNGNFL  240
            V R+ +RQW+L+ITAY+++LL++LE++DWPE++K++QRNWIGKS GA V F V D ++ +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  SVFTTRPDTLCGVSFLVMAPEHPEINHLVSEEQRSAVENYIRCVQSKSERERISETKVKS  300
            +VFTTRPDTL G ++ V+APEH+ ++ + + +Q  AV +Y R    KS+  R   +K K+
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  301  GVFIGAYAKHPITGAPLPIWVSDYVIMGYGSGVVMGVPAHDERDREFANAFALPISEVLD  360
            GV  G+YA +P+ G  +P+W++DYV+ +YG+G +M+VPAHDERD+EFA+ F L I  VL+
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  361  DNG--------QCIHSNHGDFLLNGLRGKEASDYVIAYLQKKNLGEAKVVYKLRDWLFSR  412
            +          + +H N +DF L+GL    A   ++  L+   +G+ +V Y+LRDWLFSR
Sbjct  364  GGNVEEAAFTEDGLHIN-SDF-LDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSR  421

Query  413  QRYWGEPIPIIHFEDGTCRpleddelpllppeIQDYRPKGFGQGPLANVKEWVEIHDVKT  472
            QRYWGEPIPIIH EDGT  ++ + ELPL+ P  +D RP G G++PLANV +W+E+     
Sbjct  422  QRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTR-ED  480

Query  473  NRKGRRETHTMPQWAGSCWYYLRFCDAHNSQAPWSNENERYWMPVDLYIGGAEHAVLHLL  532
              KGRRET+TMPQWAGS WYYLR+ D+HN++    +E  + W+PVD+Y+GGAEHAVLHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  533  YSRFWHRVFYEAGLVSTPEPFKKLINQGLVLATSYRIPGKGYVHPEDVREDNGK-WTTAS  591
            Y+RFWH+V+Y+ G+V+T EPF+KL+NQG++L+TSYR +  + V  + V   +G      +
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  592  GEELEVRQEKMSKSKLNGVDPQTLIDEFGADALRMYAMFSGPLDKNKLWCNHGVSGCRRF  651
            GEELE    KMSKS  N V+P+ +++++GAD+LR+Y MF GPLD +  W ++G+ G R+F
Sbjct  601  GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKF  660

Query  652  F  652
            +
Sbjct  661  L  661

710) AMIS_15100 in NC_017093


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  606 bits (2289),  Expect = 2e-174, Method: Compositional matrix adjust.
 Identities = 420/920 (46%), Positives = 579/920 (63%), Gaps = 102/920 (11%)

Query  20   GEIELRWQAYWAENGTFQAPNPVGELADPTHPRAGAPKLHVQDMFPYPSGAGLHVGHPLG  79
              IE +WQA+WA+N TF++              A+ PK+   DMFPYPSGAGLHVGHP G
Sbjct  7    TAIEPKWQAFWADNHTFKTGTD-----------ASKPKFYALDMFPYPSGAGLHVGHPEG  55

Query  80   YIGTDSYTRFQRMAGYNVLHPMGFDAFGLPAEQYAVQTGTHPAVTTAANVERYKAQLRRL  139
            Y +TD  +RF+R  G NVLHPMG DAFGLPAEQYA++TG +PA  TA N+  +K Q+  L
Sbjct  56   YTATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINAL  115

Query  140  GLAYDERRSFSTTDPEYYRWTQWIFLQVFNSWFDPELRKARPISELIERFETTDPEWAQL  199
            G++YD  R  +TTDP+YY+WTQW    +F   ++                          
Sbjct  116  GFSYDWDREVNTTDPNYYKWTQW----IFTKLYEKG------------------------  147

Query  200  SPAERRKRIDAHRLAYMSEAPVNWCPGLGTVLANEEVTPDGRSERGNFPVFKRSLKQWMM  259
                         LAY +E PVNW   LGT +ANEEV PDG SERG +PV +++++QWM+
Sbjct  148  -------------LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWML  194

Query  260  RITAYGDRLVDDLDTLDWPEPVKLMQRNWIGRSRGAHVDFPV--GSETITVFTTRPDTLF  317
            +ITAY++RL++DL+ +DWPE++K MQRNWIG+S GA+V F V      +TVFTTRPDTLF
Sbjct  195  KITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLF  254

Query  318  GATYMVLAPEHELVPVITPAQWPAGTNA-KWTGGHatpaeaiaayqaaaaakteeertaD  376
            GATY VLAPEH LV  IT ++ + +    K+ ++  +                       
Sbjct  255  GATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDL----------------  298

Query  377  GKVKTGVFTGAFAENPVNGVRVPVFIADYVLAGYGTGAIMAVPGQDERDWAFAEVFELPI  436
            +K KTGV TG++A NPVNG  +PV IADYVLA+YGTGAIMAVP++DERDW FA  F+L I
Sbjct  299  AKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDI  358

Query  437  IRTVEAPEGFEGAFTGDGPAINSDWLNGQGVTEAKAAMIAWLEENGKGRGATTYRLRDWL  496
            I  +E+ +  E+AFT DG  INSD L+G + + A A M+ WLE +G G    TYRLRDWL
Sbjct  359  IPVLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWL  418

Query  497  FSRQRYWGEPFPIVYDESGLPIALPESMLPVELPDVDDFSPRTFdpddadtepetpLSRK  556
            FSRQRYWGEP+PI+  E G + A+PES LP+ LP   D+ P            E+PL+  
Sbjct  419  FSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSG--------TGESPLANV  470

Query  557  KDWVQVELDLGDGPKMYTRETNTMPQWAGSCWYELRYLDPHNDTKLVDPANEAYWMGPRQ  616
             DW++V  + G   +   RETNTMPQWAGS WY LRY+DPHN  KL D      W+    
Sbjct  471  TDWLEVTREDGVKGR---RETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWL----  523

Query  617  DGDCGGVDLYVGGVEHAVLHLLYARFWHKVLFDLGHVSSFEPFRKLFNQGYIQAYAFQDD  676
                  VD+YVGG EHAVLHLLYARFWHKVL+DLG V++ EPF+KLFNQG I + +++D 
Sbjct  524  -----PVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDS  578

Query  677  RGFYVPAEEVVERDGKYFHGD--QEVTRSYGKMGKSLKNVVTPDEMCDQYGADTFRVYEM  734
            RG  V+++ V  RDG +FH +  +E+ ++ +KM+KSLKNVV PD++ +QYGADT+RVYEM
Sbjct  579  RGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEM  638

Query  735  AMGPLDVSRPWETRAVVGSQRFLQRAWRLVVDEETGATRVTDEPLDPKTRKVLHKVIAGV  794
             MGPLD S +W   ++ GS++FL+R  RL+   E         +LD    KV +  + +V
Sbjct  639  FMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITEE--NSGALD----KVYNETVKAV  692

Query  795  REDMAELRFNTAIAKLIELTNTLTPLPTVSREAVEPLVLMLSPFAPHMAEELWGKLGHTG  854
             E++ +++FNTAIA+L+ + N+      +  +    +V +++PFAPH++EELW  L  +G
Sbjct  693  TEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASG  752

Query  855  -TLAYADFPVADPAQLVADSITYPVQVNGKVRGRVEVSPETgeaevraaaleavaealag  913
             +++Y   P  D ++LV + +   VQ++GKV++++ V+ + +  E++  AL         
Sbjct  753  ESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEI  812

Query  914  rePK--KVIVVKGRLVSVVV  931
                  KVI V  +LV++V+
Sbjct  813  AGKDIIKVIAVPNKLVNIVI  832

711) Syn7502_00016 in NC_019702


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  606 bits (2290),  Expect = 2e-174, Method: Compositional matrix adjust.
 Identities = 377/854 (45%), Positives = 567/854 (67%), Gaps = 31/854 (3%)

Query  6    YNPQTIEPKWQQIWKEQQLDQTPEPSDDRPKFYALSMFPYPSG-SLHMGHVRNYTITDAI  64
            Y+  +IEPKWQ +W +++  +T      +PKFYAL MFPYPSG +LH+GH   YT TD +
Sbjct  4    YDHTAIEPKWQAFWADNHTFKT-GTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDIL  62

Query  65   ARFKRMSGYRVLHPMGWDAFGLPAENAAIDRNTHPATWTFQNIEQMRSQLKQIGLSYDWD  124
            +RFKR  G  VLHPMGWDAFGLPAE+ A+D   +PA  T +NI + + Q++ +G+SYDWD
Sbjct  63   SRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWD  122

Query  125  RELATCAPDYYHWTQWLFLEFLGAGLAYQKEATVNWDPIDQTVLANEQVDSDGRSWRSGA  184
            RE+ T  P+YY WTQW+F  +   GLAY+ E  VNW     T +ANE+V +DG S R+G 
Sbjct  123  REVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGY  182

Query  185  KVEKRKLRQWFFKITDYADRLLQDLDQLPHWPERVKTMQANWIGKSIGAELTFPIVQPSE  244
             V ++ +RQW +KIT YA+RLL+DL+++ +WPE +K MQ NWIGKS GA++TF +    +
Sbjct  183  PVVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKV---KD  238

Query  245  TAAKITVFTTRPDTIYGVSYVVLAPEHPLVKEITTAEQKDQVEAFITAVASISEIDRTAE  304
            T   +TVFTTRPDT++G +Y VLAPEH+LV  ITT++Q + V  +    +  S++ RT  
Sbjct  239  TDKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDL  298

Query  305  DKPKQGVFTGGYVINPFTNQEVPIWIADYVLLEYGTGAVMGVPAHDVRDFAFAKQYGLPI  364
             K K GV TG+Y INP   +E+P+WIADYVL  YGTGA+M+VPAHD RD  FAKQ+ L I
Sbjct  299  AKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDI  358

Query  365  QQVIISNSQTEVKELKSAYTETGIMIQSDRFNGLDSVTAKTKIIEYAEANNWGKARIQYR  424
              V+ + +  E     +A+TE G+ I+SD ++GLD  +A +K++E  EA+  G+  + YR
Sbjct  359  IPVLEGGNVEE-----AAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYR  413

Query  425  LRDWLISRQRYWGCPIPIIHCPDCGIVPVPDQDLPVELPENVEL--TGRGGSPLAQLSSW  482
            LRDWL+SRQRYWG PIPIIH  D    +VP+ +LP+ LP   ++  +G G SPLA+++ W
Sbjct  414  LRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDW  473

Query  483  VNVKCPKCGTHAKRETDTMDTFIDSSWYYLRFTDAKNPKEAFTKAKVNDWMSVDQYVGGV  542
            ++V     G  ++RET+TM    +SSWYYLR+ D+ N         +++W++VD YVGG 
Sbjct  474  LEVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGA  532

Query  543  EHAILHLLYSRFFTKVLSDRHLLNFNEPFQRLLTQGMVQGLTYSNPKKEGKDKWISSTLV  602
            EHA+LHLLY+RF  KVL D  ++  +EPFQ+L+ QGM+ G +Y    +++++  +++  V
Sbjct  533  EHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY----RDSRGALVATDKV  588

Query  603  NPADPR--DPETGEPLEVGYATMSKSKGNGVSPQQVIEKYGADVMRMFVLFKAPPEKDLE  660
            +  D    + ETGE LE + A MSKS  N V+P++V+E+YGAD +R++ +F +P +  + 
Sbjct  589  EKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIA  648

Query  661  WDEADVEGQWRFLNRIWRLVTEFVEAQPKITDIPDKNLKRAIHTAIKEITEDLTGDYQLN  720
            W E ++EG ++FL+R+ RL+T        IT+     L +  + ++K +TE++ ++ ++N
Sbjct  649  WSEEGLEGSRKFLDRVYRLITT-----KEITEENSGALDKVYNETVKAVTEQV-DQMKFN  702

Query  721  TAISELMKLSNALQDSSDKASFTFKEGIETLLILLAPFAPHIACELWSMLGYQNTILTH-  779
            TAI++LM     + ++++K    F +    ++ L+APFAPH++ ELW  L      ++  
Sbjct  703  TAIAQLM----VFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYV  758

Query  780  KWLVHDPNALIVDEITLVIQINGKVRGSIQVPSGADKTALEEYARNSEVAQKYLEGKEIK  839
             W   D + L+ +++ +V+QI+GKV++ + V+ +  +  L+E A  +E  Q  + GK+I 
Sbjct  759  PWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDII  818

Query  840  KAIAVPGKLVNFVI  853
            K IAVP KLVN+VI
Sbjct  819  KVIAVPNKLVNIVI  832

712) MCYN0372 in NC_019949


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  605 bits (2286),  Expect = 3e-174, Method: Compositional matrix adjust.
 Identities = 391/845 (47%), Positives = 564/845 (67%), Gaps = 67/845 (7%)

Query  11   VTMYKHKEIEKKWQNIWETTKAFKTTEHNDK-KYYVLDMFPYPSAAGLHVGHPEGYTASD  69
            +T Y H  IE KWQ +W    +FKT  +  K K+Y LDMFPYPS+AGLHVGHPEGYTA+D
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  70   IIARYKRLNGYDVLHPIGWDAFGLPAEQYALKTGHHPASFTQENIKTFKKQLKSLGFSFD  129
            I++R+KR +G +VLHP+GWDAFGLPAEQYA+ TG++PA FT ENI  FK+Q+++LGFS+D
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  130  WDKEIDTTDPKFYKWTQWIFKKLYEHNLAEIKKIDVNWCQELGTVLANEEVIIDEKGNRV  189
            WD+E++TTDP++YKWTQWIF KLYE  LA    + VNW +ELGT +ANEEV+ D      
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDG----T  176

Query  190  SERGNFPVIRKPMKQWVLKITKYAEKLLDGLEKLEFSESLKSLQENWIGKSSGHVIKFKI  249
            SERG +PV+RKPM+QW+LKIT YAE+LL++LE ++ +ES+K +Q NWIGKS+G  + FK+
Sbjct  177  SERGGYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKV  236

Query  250  ENSNQTIDVFTTRIETILGASFIVVAPEHEllnnlksnkninEYLEYTKTL---SDRDRI  306
             ++++ + VFTTR +T++GA++ V+APEH L++ + ++ + +   +Y +     SD  R 
Sbjct  237  KDTDKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLART  296

Query  307  SNIKQKTGVYTGINAINPMTSELIPIWTSDYVLKNYGTGAIMGVPGVDERDQDFALKFNL  366
               K+KTGV TG  AINP+ +  +P+W +DYVL +YGTGAIM+VP+ DERD +FA +FNL
Sbjct  297  DLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNL  356

Query  367  DIKNIITGE-------VDHEYLVNCGSYTGLDLRTAKEKISQKLINEHQAYEQISYKIRD  419
            DI  ++ G         ++   +N +   GLD  +A  K+ + L  E  + E+++Y++RD
Sbjct  357  DIIPVLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WIFSRQRYWGEPFP-VYFDENNNIYLEENIVE--LPYMENIKPSNTGESPLANNKDWLYF  476
            W+FSRQRYWGEP+P +  ++  +  + E+ +   LP   +I+PS TGESPLAN  DWL  
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  EK-DGRKYKRETNTMPQWAGSSWYFLAYIMKNADGSYLDINSKEAYQRFEKWLPVDLYIG  535
             + DG K +RETNTMPQWAGSSWY+L YI  +      D       + + +WLPVD+Y+G
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADE------ELLKQWLPVDIYVG  530

Query  536  GQEHAVGHLIYSRFWHKFLYDIKILPVDEPFLKVVNQGMILGP-----------------  578
            G EHAV HL+Y+RFWHK LYD+ ++P  EPF K+ NQGMILG                  
Sbjct  531  GAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEK  590

Query  579  ----------------DGQKMSKSRGNVINPDEIIDEYGADTLRVYEMFMGPLAETKEWS  622
                               KMSKS  NV+NPD+++++YGADTLRVYEMFMGPL  +  WS
Sbjct  591  RDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWS  650

Query  623  VESIRGIRKWLDRVEVIISKFSNDSTLINENHKDNKFISLWQSTIKEVTIAINTLKFNIA  682
             E++ G RK LDRV  +I+  +++ T  N    D+ +    + T+K VT  ++ +KFN A
Sbjct  651  EEGLEGSRKFLDRVYRLIT--TKEITEENSGALDKVY----NETVKAVTEQVDQMKFNTA  704

Query  683  ISKLMVFINSLYKVEKLHSIKPLVDFCIMFSTLAPHLSEELLEQLNQK--QIKDQKWPNV  740
            I++LMVF+N+  K +KL S  +  +F  +++ +APHL+EEL + L      I    WP+ 
Sbjct  705  IAQLMVFVNAANKEDKLFSDYA-KGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSY  763

Query  741  DEKLIQNSIVKIVVQVNGKVRGIFEKEGNLSEEEIFTMALSQPNVKKFIDGHEIKRKQYI  800
            DE  + ++ V IVVQ++GKV++ +    +LS EE+  +AL++ +V+  I G +I +   +
Sbjct  764  DESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAV  823

Query  801  KDKII  805
             +K++
Sbjct  824  PNKLV  828

713) leuS in NC_009454


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  605 bits (2286),  Expect = 4e-174, Method: Compositional matrix adjust.
 Identities = 385/862 (45%), Positives = 560/862 (65%), Gaps = 71/862 (8%)

Query  5    YDFKEIEEKWQARWAAQDLYAVPDYSDRPKYYCLEMFPYPSGK-LHMGHVRNYSIGDVVA  63
            YD   IE KWQA WA ++ +     + +PK+Y L+MFPYPSG  LH+GH   Y+  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RFKTMQGYHVLHPMGWDAFGLPAENAAIKHGGVHPAEWTLDNIESMRAQLKQLGISYDWN  123
            RFK  QG +VLHPMGWDAFGLPAE+ A+  G  +PAE T +NI + + Q++ LG+SYDW+
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGN-DPAEFTAENIANFKRQINALGFSYDWD  122

Query  124  REVATCHPGYYRWTQWLFLQLFHNGLAYKKKAAVNWCPGCATVLANEQV-KDGGCERCKA  182
            REV T +P YY+WTQW+F +L+++GLAY    +VNW    +T +ANE+V  DG  ER   
Sbjct  123  REVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGY  182

Query  183  PVEKRELEQWFFKITDYAERLLKDLELLEGWPEKVKIMQENWIGRSEGAEIDFKVEGSDD  242
            PV ++ + QW +KIT YAERLL DLE ++ WPE +K MQ NWIG+S GA++ FKV ++D 
Sbjct  183  PVVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDK  241

Query  243  IITVYTTRPDTVFGVTYMVLAPEHPLVEKLIAGSKQEAEIKEFIRKVRNLREIDRTSTEA  302
             +TV+TTRPDT+FG TY VLAPEH+LV+  I+ S Q   + ++ R+     ++ RT    
Sbjct  242  DFTVFTTRPDTLFGATYAVLAPEHALVDA-ITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  303  EKVGMPTGAHCINPLTGEKVPVLIANYVLMEYGTGCVMGVPAHDQRDFEFARKYGYPIRV  362
            EK G+ TG+  INP+ G  +PV IA+YVL  YGTG +M+VPAHD+RD EFA+++   I  
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  363  VIQPPGVELDPAAMEAAYEEEGFLVNSGPFSGMPNKEAIRAITRHLEEKGRGRFRVTYRL  422
            V++   VE      EAA+ E+G+ +NS+ + G+ +  AI  +   LE  G G   VTYRL
Sbjct  361  VLEGGNVE------EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRL  414

Query  423  RDWLISRQRYWGAPIPIIYCDRCGTVPVPESDLPVLLPMDVEFKP--TGQSPLAECPEFV  480
            RDWL+SRQRYWG PIPII  +   + +VPES+LP++LP+  +++P  TG+SPLA+  + +
Sbjct  415  RDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWL  474

Query  481  NAACPSCGGPGKRETDTMDTFMCSSWYYYRYTSPRDNDAPWDRNKVDYWLPVDQYIGGVE  540
            + +    G  G+RET+TM     SSWYY RY  P++ +   D + +  WLPVD Y+GG E
Sbjct  475  EVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAE  533

Query  541  HAILHLLYSRFFTKVLYDLKLVSNLEPFSNLLTQGMVL-------------------KDG  581
            HA+LHLLY+RF  KVLYDL +V+  EPF +L+ QGM+L                   +DG
Sbjct  534  HAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDG  593

Query  582  ---------------AKMSKSRGNVVSPEDIVARYGADTARLFILFAAPPERDLEWSDQG  626
                           AKMSKS  NVV+P+D+V +YGADT R++ +F +P +  + WS++G
Sbjct  594  SFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEG  653

Query  627  VEGCYRFLNRVWRLVMPLAGLLKEAPAAVSGKLVGANREMRRVTHSTIKKVTEDISARFN  686
            +EG  +FL+RV RL+       KE     SG L        +V + T+K VTE++  + +
Sbjct  654  LEGSRKFLDRVYRLITT-----KEITEENSGAL-------DKVYNETVKAVTEQVD-QMK  700

Query  687  FNTAVSAIMELVNALYQFREIPESDRNPAVLREAVESlllllAPFAPHITEELWEATGHR  746
            FNTA++ +M +VNA         ++++  ++ +   +++ L+APFAPH+ EELW+A    
Sbjct  701  FNTAIAQLMVFVNA---------ANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTAS  751

Query  747  G-SIHLQPWPSYDPEAIAEDEITIVVQINGRVRERLLVPAGITPQEMQDRVMKEPRVMRM  805
            G SI   PWPSYD   + E+++ IVVQI+G+V+ +L+V+ +++ +E+Q+  + + +V   
Sbjct  752  GESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAE  811

Query  806  VEGKKVAKVITVPGKLVNIVIK  827
            + GK + KVI+VP KLVNIVIK
Sbjct  812  IAGKDIIKVIAVPNKLVNIVIK  833

714) Mahau_1713 in NC_015520


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  605 bits (2286),  Expect = 4e-174, Method: Compositional matrix adjust.
 Identities = 377/861 (44%), Positives = 560/861 (66%), Gaps = 70/861 (8%)

Query  3    YDFKAIEGRWQDEWEKTKAFKATEDNQKPKYYMLEMFPYPSGK-LHMGHVRNYSIGDVIA  61
            YD  AIE +WQ  W    +FK+  D  KPK+Y L+MFPYPSG  LH+GH   Y+  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  62   RYKRMQGYNVLHPMGWDAFGLPAENAAIKNGVEPSKWTWDNINNMRRQLKQLGISYDWDR  121
            R+KR QG NVLHPMGWDAFGLPAE+ A+  G +P+  T +NI N +RQ++ LG+SYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  122  EVASCHPAYYKWTQWLFLQFYKNGLAYKKKARVNWCPSCGTVLANEQVVA-GCCERCGTP  180
            EV + +P YYKWTQW+F ++Y +GLAY     VNW    GT +ANE+V++ G  ER G P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  181  VGKKDLEQWFFKITDYAERLLQDIDKLDGWPDKVKSMQRNWIGKSYGAEVIFSIEDVKNE  240
            V +K + QW +KIT YAERLL+D++ +D WP+ +K MQRNWIGKS GA+V F + D  ++
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  241  KITVFTTRPDTIFGVSFVVLAPEHPLIEKLAKKTPYYKQVKDFQKKIEALDEITRTSTEA  300
             +TVFTTRPDT+FG ++ VLAPEH+L++ ++        V D++++     +++RT    
Sbjct  243  -FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQ-AEAVADYKRQASLKSDLARTDLAK  300

Query  301  EKEGVFIGRYAINPMNGARIPIYTANYVLMEYGTGAVMGVPAHDGRDFEFAKKYGLPIVP  360
            EK GV  G YAINP+NG  +P+  A+YVL  YGTGA+M+VPAHD RD EFAK++ L I+P
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  361  VIKPADAAQDFDLEQAYEDDGIMINSGQFNGFDNRDGIERVISYMEENGLGRRKTTYKLR  420
            V+  ++       E A+ +DG+ INS+ ++G+D+  +I +++  +E +G+G  + TY+LR
Sbjct  361  VLEGGNVE-----EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  421  DWLISRQRYWGAPIPIVYCEKCGEVPVPEDQLPVMLPT--DVVFTGTGQSPLTTSESFVN  478
            DWL+SRQRYWG PIPI+  E     +VPE +LP++LP   D+  +GTG+SPL+     ++
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  479  TKCPICGGPARREVDTMDTFVCSSWYYLRYTDPRNDKEAFNKEKASYWMPVDQYVGGVEH  538
                  G  +RRE +TM     SSWYYLRY DP+N     + E    W+PVD YVGG EH
Sbjct  476  VTRE-DGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEH  534

Query  539  AILHLLYSRFFTKVLHDLGLVDVNEPFVNLLTQGMVL-------------------KDGS  579
            A+LHLLY+RF  KVL DLG+V  +EPF +L+ QGM+L                   +DGS
Sbjct  535  AVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGS  594

Query  580  ---------------KMSKSKGNIVSPEDIVDKYGADTARLFILFAAPPERDLEWSDQSV  624
                           KMSKS  N+V+P+D+V++YGADT R++ +F +P +  + WS++++
Sbjct  595  FFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGL  654

Query  625  EGCFRFLNRVWRLVDQYADAVKEWVENGKPETDLISDGDKELRYIINYTIKKVSDDIAER  684
            EG  +FL+RV RL+                  ++  +    L  + N T+K V++++ + 
Sbjct  655  EGSRKFLDRVYRLI---------------TTKEITEENSGALDKVYNETVKAVTEQVDQM  699

Query  685  YNFNTAISAIMEMVNAMYQSDTADSPSTVMMEAVETLLLLLAPFVPHISEEMWHR-TGHG  743
             +FNTAI+ +M  VNA      A+    +  +    ++ L+APF PH++EE+W+  T+ G
Sbjct  700  -KFNTAIAQLMVFVNA------ANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASG  752

Query  744  APLYLQAWPIYDADALvkqqvevvvqvNGKVRDKVMMPAGADEDKMKILAMQSSKVAASI  803
             ++   +WP YD   LV ++VE+VVQ++GKV+ K++++ +   + ++ +A+ + KV A I
Sbjct  753  ESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEI  812

Query  804  ADKNIIKVVSVPDKLVNIVVR  824
            A+K+IIKV++VP+KLVNIV++
Sbjct  813  AGKDIIKVIAVPNKLVNIVIK  833

715) leuS in NC_010546


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  604 bits (2280),  Expect = 1e-173, Method: Compositional matrix adjust.
 Identities = 380/854 (45%), Positives = 574/854 (68%), Gaps = 32/854 (3%)

Query  5    YNAAEIEQKWQQDWVNQGLDKTPENSDKPKFYALSMFPYPSG-NLHMGHVRNYVITDVIA  63
            Y+ + IE KWQ  W ++   KT  ++ KPKFYAL MFPYPSG  LH+GH   Y  TD+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RLKRLQGYRVLHPMGWDAFGLPAENAAIDRNIPPADWTYKNIAQMKQQLQTLGLSIDWDR  123
            R+KR QG  VLHPMGWDAFGLPAE+ A+D    PA+ T  NIA+ K+Q+++LG+S DWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVATCSPDYYKWTQWLFLQFYQAGLAYQKEAAVNWDPIDQTVLANEQVDSEGYSWRSGAK  183
            EV T  P+YYKWTQW+F ++Y+ GLAY+ E +VNW     T +ANE+V ++G S R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  184  VERKLLRQWFFKITDYAEQLLTDLDKLTGWPDRVKLMQENWIGKSVGAYLEFPVKGSEEK  243
            V RK +RQW +KIT YAE+LL DL+ + +WP+ +K MQ NWIGKS GA + F VK+++  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  244  IAVFTTRPDTVYGVTYVVLAPEHPLTPKVTTEGQKEAVEAFIEEVSNESEIERTAEDKPK  303
            ++VFTTRPDT++G TY VLAPEH+L   +TT +Q EAV  +  + S  S++ RT   K K
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEK  302

Query  304  RGILTGGTAVNPFNGEEIPILIADYVLYEYGTGAVMGVPAHDTRDFKFATEKELPIKVVI  363
             G+ TG+ A+NP NG E+P+ IADYVL  YGTGA+M+VPAHD RD  FA + +L I  V+
Sbjct  303  TGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL  362

Query  364  VPENSEDNNPTLTEAYTEPGIMVNSGEFNGMQSTEGKTAIINYAEKQGYGKARIQYRLRD  423
               N E+       A+TE G+ +NS+ ++G++ + + + +++  E +G G+  + YRLRD
Sbjct  363  EGGNVEEA------AFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  424  WLISRQRYWGCPIPVVHCPSCGTVAVPDADLPVKLPENVEF--TGRGASPLAKMEDWINV  481
            WL+SRQRYWG PIP++H     + AVP+++LP+ LP   ++  +G G SPLA++ DW++V
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  482  PCPSCGEPAKRETDTMDTFIDSSWYYLRYTDAMNDQEAFKLEKANDWMNVDQYVGGIEHA  541
                 G  ++RET+TM    +SSWYYLRY D+ N +     E  ++W+ VD YVGG EHA
Sbjct  477  TRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  542  ILHLLYSRFFTKVLRDRGLVNVDEPFKRLLTQGMVQAMAYKNPKTGKYIPVDKVNPESPK  601
            +LHLLY+RF  KVL D G+V   EPF++L+ QGM+ + +Y++++ G  ++ DKV+     
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSR-GALVATDKVEKRDGS  594

Query  602  --DPDTGDDLEVFYEKMSKSKYNGVDPQKVLGKYGADTARMFILFKAPPEKDLEWDDADV  659
              + +TG++LE    KMSKS  N V+P+ V+ +YGADT R++ +F +P +  + W + ++
Sbjct  595  FFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGL  654

Query  660  EGQFRFLNRVWRLVNGYEKKQGEVISNKELSKEEKD-LRRAIHTAIKEISEDLEGDYQFN  718
            EG  +FL+RV RL           I+ KE++ E+ + L +  + ++K ++E+++ + +FN
Sbjct  655  EGSRKFLDRVYRL-----------ITTKEITEENSGALDKVYNETVKAVTEQVD-QMKFN  702

Query  719  TAVSELMKLSNALNDAKCINSEVYQEGIETLLILLAPFAPHIAEELWHNL-GHETSIHLE  777
            TA+++LM + NA N     +  ++ +    ++ L+APFAPH++EELW+ L +   SI   
Sbjct  703  TAIAQLMVFVNAANK----EDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYV  758

Query  778  TWPQVDPDALVVDEITLVIQIMGKTRGTIQVPANSSKEELEKLARESDIGQRNLDGKEVK  837
             WP  D   LV +++ +V+QI GK ++ + V+ + S+EEL+ +A  ++  Q ++ GK++ 
Sbjct  759  PWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDII  818

Query  838  KVIVVPGKLVNFVV  851
            KVI VP KLVN+V+
Sbjct  819  KVIAVPNKLVNIVI  832

716) Pse7367_0963 in NC_019701


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  604 bits (2282),  Expect = 8e-174, Method: Compositional matrix adjust.
 Identities = 382/850 (45%), Positives = 574/850 (68%), Gaps = 26/850 (3%)

Query  5    YEPQQIEPKWQQSWAEQQLDLAPETDDRPKFYALSMFPYPSG-NLHMGHVRNYTITDAIA  63
            Y+   IEPKWQ  WA+++   +     +PKFYAL MFPYPSG  LH+GH   YT TD ++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYKRMQGYRVLHPIGWDAFGLPAENAAIDRGTHPAAWTYKNIEQMRALLKQVGLSYDWER  123
            R+KR QG  VLHP+GWDAFGLPAE+ A+D G +PA  T  NI + +  ++ +G+SYDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCAPDYYHWTQWLFLQFWDAGLAYQKEATVNWDPIDHTVLANEQVDSDGKSWRSGAI  183
            E+ T  P+YY WTQW+F ++ + GLAY+ E  VNW     T +ANE+V +DG S R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  184  VEKKKLRQWFFKITDYAEQLLNDLDKLTDWPDRVKTMQANWIGKSVGAELTFPVVGAAQD  243
            V +K +RQW +KIT YAE+LL+DL+ + DWP+ +K MQ NWIGKS GA++TF V ++ +D
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  244  IAITVFTTRPDTVYGVSYVVLAPEHPLVKDLTSNKHQAAVEKFIAEVAAQSEIDRTAEDK  303
              +TVFTTRPDT++G +Y VLAPEH+LV  +T++ +  AV  +  + + +S++ RT   K
Sbjct  243  --FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  304  PKRGMAIGAMALNPFTGKEIPIWIADYVLYEYGTGAVMGVPAHDVRDFAFAQQYNLSIQT  363
             K G+  G+ A+NP  GKE+P+WIADYVL  YGTGA+M+VPAHD RD  FA+Q+NL I  
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  364  VIVPQEQEAQTDLAEAYTDPGVMVNSAEFDGLDSPaaktkiiakaeaQGWGKARIQYRLR  423
            V+   + E       A+T+ G+ +NS  +DGLD ++A +K++   EA+G G+  + YRLR
Sbjct  361  VLEGGNVE-----EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  424  DWLISRQRYWGCPIPIIHCPDCGVVPVPAADLPVELP--ENVQLSGRGASPLTQLEDWLQ  481
            DWL+SRQRYWG PIPIIH  D    +VP ++LP+ LP   +++ SG G SPL+++ DWL+
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  482  VKCPSCGAAARRETDTMDTFIDSSWYFLRFTDAKNDKAIFDLDKVNDWMPVDQYVGGVEH  541
            V     G  +RRET+TM    +SSWY+LR+ D+ N   + D + +++W+PVD YVGG EH
Sbjct  476  VTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEH  534

Query  542  AILHLLYSRFFTKVLRDRGLLKFDEPFQRLLTQGMVQGMTYRNAVTGKVVPANLIDPE-N  600
            A+LHLLY+RF  KVL D G++   EPFQ+L+ QGM+ G +YR++  + V   ++   + +
Sbjct  535  AVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGS  594

Query  601  LVDPETGDRLTAGYETMSKSKHNGVSPVEVIEKYGRDTVRMFTLFKAPPEKDLEWDAADV  660
            + + ETG+ L  +   MSKS  N V+P +V+E+YG DT+R++ +F +P +  + W   ++
Sbjct  595  FFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGL  654

Query  661  EGQSRFLGRVWRLVNGFTAAGGANQATGKPDKDLRRAIHIAIKEVSEDLDGDYQLNTAIS  720
            EG  +FL+RV RL+        +++ T      L +  + ++K V+E++D + ++NTAI+
Sbjct  655  EGSRKFLDRVYRLIT-------TKEITEENSGALDKVYNETVKAVTEQVD-QMKFNTAIA  706

Query  721  ELMKLSNALQDSKNTKSATYAEGIETLLLLMAPFAPHIAEELWHGL-GHEQSVHLQSWPK  779
            +LM + NA  +  +   + YA G   ++ L+APFAPH++EELW++L +  +S+   +WP 
Sbjct  707  QLMVFVNA-ANKEDKLFSDYAKG---FVQLIAPFAPHLGEELWQALTASGESISYVPWPS  762

Query  780  LDPTALVVSEITLVVQVNGKVRGNMQVPADADRQALIEYAKGCEAAQRYLEGKEIKKAIA  839
             D + LV +++ +VVQ++GKV++++ V+ D  R+ L E A + E  Q  + GK+I K IA
Sbjct  763  YDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIA  822

Query  840  VPGKLVNFVV  849
            VP KLVN+V+
Sbjct  823  VPNKLVNIVI  832

717) leuS in NC_006576


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  604 bits (2281),  Expect = 9e-174, Method: Compositional matrix adjust.
 Identities = 391/849 (47%), Positives = 568/849 (67%), Gaps = 27/849 (3%)

Query  21   YDPQAIETKWQQSWAAAQLDRTPEADDRPKFYALSMFPYPSG-NLHMGHVRNYTITDAIA  79
            YD  AIE KWQ  WA  +  +T     +PKFYAL MFPYPSG  LH+GH   YT TD ++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  80   RVKRRQGFRVLHAMGWDAFGLPAENAAIDRGVQPADWTYQNVAQMREQLKQLGLSYDWDR  139
            R KR QG  VLH+MGWDAFGLPAE+ A+D G +PA+ T +N+A+ + Q++ LG+SYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  140  EVTTCSPDYYRWTQWLFLQFFEAGLAYQKEATVNWDPIDQTVLANEQVDSEGRSWRSGAK  199
            EV T  P+YY+WTQW+F +++E GLAY+ E  VNW     T +ANE+V ++G S R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  200  VERRQLKQWFLKITDYAEELLQDLDQLTGWPERVRLMQANWIGKSTGAYLEFPIVNSSDR  259
            V R+ ++QW LKIT YAE LL+DL+++ +WPE ++ MQ NWIGKSTGA + F + ++   
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  260  VKVFTTRPDTVYGVSYVVLAPEHPLVTQVTTPEQQTAVAAFAAEVSQTSELERTAEDRPK  319
              VFTTRPDT++G +Y VLAPEH+LV  +TT++Q  AVA +  + S  S+L RT   + K
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEK  302

Query  320  RGVPTGGFVTNPFTGQAVPIWIADYVLVEYGTGAVMGVPAHDSRDFAFAQRYGLPVQPVI  379
             GV TG++  NP  G+ +P+WIADYVL  YGTGA+M+VPAHD RD  FA+++ L + PV+
Sbjct  303  TGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL  362

Query  380  QPTEGAIAEPWPAPFTEAGVMVNSGQFDGLSSTeakakiiafaeeQGWGQAHVQYRLRDW  439
            +   G + E   A+FTE G+ +NS+ +DGL  + A AK++   E +G G+ +V YRLRDW
Sbjct  363  E--GGNVEE---AAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDW  417

Query  440  LISRQRYWGCPIPIVH--CPDCGPVAAADLPVQLP--DSVQFSGRGPSPLAQLEDWVTTT  495
            L+SRQRYWG PIPI+H       +V+ ++LP+ LP    ++ SG G SPLA++ DW+  T
Sbjct  418  LFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT  477

Query  496  CPSCGKPARRETDTMDTFMCSSWYYLRYSDASNPEIAFTKDKVNDWLPVDQYVGGIEHAI  555
                 K +RRET+TM     SSWYYLRY D+ N E     + +++WLPVD YVGG EHA+
Sbjct  478  REDGVK-GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  556  LHLLYSRFFTKVLRDRGLLSFDEPFKRLLTQGMVQGLTYKNPKTGKYVPSDRISDPSQP-  614
            LHLLY+RF  KVL D G+++  EPF++L+ QGM+ G +Y++++ G  V++D++     + 
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSR-GALVATDKVEKRDGSF  595

Query  615  VDPDTGDRLEVFFEKMSKSKYNGVDPARVLDRYGADTARMFILFKAPPEKDLEWDDADVE  674
             + +TG+ LE    KMSKS  N V+P  V+++YGADT R++ +F +P +  + W + ++E
Sbjct  596  FHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLE  655

Query  675  GQFRFLNRVWRLVQTASQVeattaaddkaekdLRRAVHTAIQAFTEDLEEDYQLNTAIAE  734
            G  +FL+RV RL+ T           +     L +  + +++A TE++++  ++NTAIA+
Sbjct  656  GSRKFLDRVYRLITTKE-------ITEENSGALDKVYNETVKAVTEQVDQM-KFNTAIAQ  707

Query  735  LMKLTNALNDAPMPGSPAYLKGVQTLVLLLAPFAPHIAEELWQQL-GGERSVHLEGWPVL  793
            LM + NA N       + Y KG   +V L+APFAPH++EELWQ L ++  S+    WP  
Sbjct  708  LMVFVNAANKEDKL-FSDYAKG---FVQLIAPFAPHLGEELWQALTASGESISYVPWPSY  763

Query  794  DESALIVDEIPLVIQIMGKTRGTITVPASADRDQLQQLAKNSEIAQRWLDGQTIRKVIVV  853
            DES L+ +++ +V+QI GK ++ + V+    R++LQ++A  +E  Q  + G+ I KVI V
Sbjct  764  DESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAV  823

Query  854  PGKLVNFVI  862
            P KLVN+VI
Sbjct  824  PNKLVNIVI  832

718) Cha6605_3873 in NC_019697


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  603 bits (2279),  Expect = 1e-173, Method: Compositional matrix adjust.
 Identities = 386/873 (45%), Positives = 577/873 (67%), Gaps = 49/873 (5%)

Query  5    YNPAEIESKWQQSWTEQNLYKTDITSSKPKYYALSMFPYPSG-NLHMGHVRNYVITDVVA  63
            Y+ + IE+KWQ  W++++ +KT+  +SKPK+YAL MFPYPSG  LH+GH   Y  TD+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RQKRMQGHRVLHPMGWDAFGLPAENAAIERGIHPATWTYQNIAHMRGQLQKLGLSIDWDR  123
            R KR QGH VLHPMGWDAFGLPAE+ A++ G +PA  T +NIA+ + Q++ LG+S DWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVATCSPEYYRWTQWIFLKFYEGGLAYQKDGMVNWDPIDQTVLANEQVDSEGRSWRSGAI  183
            EV T  P+YY+WTQWIF K+YE GLAY+ +  VNW     T +ANE+V ++G S R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  184  VEKKALKQWYFKITEYAEQLLTDLEQLSGWPEKVRIMQANWIGKSIGANLEFPIVGTSEK  243
            V +K+++QW +KIT YAE+LL DLE++ +WPE ++ MQ NWIGKS GAN+ F + +T   
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  244  IAVFTTRPDTVYGVSYVVLAPEHPLTAQVTTSEQKAAVDAFVEEIKSQSEIDRTAEDKPK  303
            ++VFTTRPDT++G +Y VLAPEH+L   +TTS+Q  AV  +  +   +S++ RT   K K
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEK  302

Query  304  RGVATGAMAINPFTGAEVPIWIADYVLYEYGTGAVMGVPAHDVRDFKFAKQYQLPINQVI  363
             GV TG+ AINP  G E+P+WIADYVL  YGTGA+M+VPAHD RD  FAKQ++L I  V+
Sbjct  303  TGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL  362

Query  364  AAPDRDSSEPLAAAYTDAGTMINSNQFDGLDSVTAKQSIIEYAEQQGYGNGKIQYRLRDW  423
             + + +      AA+T+ G  INS+ +DGLD  +A   ++E  E +G GN ++ YRLRDW
Sbjct  363  EGGNVE-----EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDW  417

Query  424  LISRQRYWGVPIPIVHCPKCGAVPVPEADLPVKLP--EDVEFTGKGGNPLAQLESWVNVP  481
            L+SRQRYWG PIPI+H     + +VPE++LP+ LP   D+  +G G +PLA++  W++V 
Sbjct  418  LFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT  477

Query  482  CPTCGTPAKRETDTMDTFVDSSWYFLRYPDAGNDKQIFDPNITNDWMPVDQYVGGIEHAV  541
                G  ++RET+TM    +SSWY+LRY D+ N  ++ D ++ ++W+PVD YVGG EHAV
Sbjct  478  RED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  542  LHLLYARFFTKIVRDFGAGDKGKTSGALRSGSPTMEVRQDKFLNFDEPFKKLLTQGMVQA  601
            LHLLYARF  K++ D+G               PT            EPF+KL+ QGM+ +
Sbjct  537  LHLLYARFWHKVLYDLGV-------------VPTK-----------EPFQKLFNQGMILG  572

Query  602  TTYKNPQTGKYISQNTIFDVNNP-IDPTTGDRLEVSFEKMSKSKYNGIDPEEVLGKYGAD  660
            T+Y++++ G  ++ + +   + + ++  TG+ LE +  KMSKS  N ++P++V+ +YGAD
Sbjct  573  TSYRDSR-GALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGAD  631

Query  661  TARMFILFKAPPEKDLEWDEADVEGQFRFLNRMWRLAIGYKPTTANTGELSKSEKDLRRF  720
            T R++ +F +P +  + W E ++EG  +FL+R+ RL      T  N+G L K        
Sbjct  632  TLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALDKV-------  684

Query  721  VHHAIQAITEDLDGDYQFNTAISELMKLSNAITDADCKDSPVYADAIETLMLLAAPFAPH  780
             +++++A+TE++D + +FNTAI++LM     + +A  K+  +++D    ++ L APFAPH
Sbjct  685  YNETVKAVTEQVD-QMKFNTAIAQLM----VFVNAANKEDKLFSDYAKGFVQLIAPFAPH  739

Query  781  MTEELWQ-LTGHSGSIHEQAWRQFDPAALEADEITLVIQIMGKTRGTIQVPATKDSATLE  839
            + EELWQ LT+ + SI   +W  +D + L  +++ +V+QI GK ++ + V+       L+
Sbjct  740  LGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQ  799

Query  840  AYARESAITKKFAEGKEIKKVIVVPGKLVNFII  872
              A  +   +    GK+I KVI VP KLVN++I
Sbjct  800  EVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

719) leuS in NC_011726


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  603 bits (2279),  Expect = 1e-173, Method: Compositional matrix adjust.
 Identities = 379/855 (45%), Positives = 583/855 (69%), Gaps = 31/855 (3%)

Query  5    YNAAAIEQKWQQDWVKQGLDKTPENSNKPKFYALSMFPYPSG-NLHMGHVRNYVITDVIA  63
            Y+ +AIE KWQ  W  +   KT  +++KPKFYAL MFPYPSG  LH+GH   Y  TD+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RLKRLQGYRVLHPMGWDAFGLPAENAAIDRGIPPAEWTYKNMSQMKQQLQTLGLSIDWER  123
            R+KR QG  VLHPMGWDAFGLPAE+ A+D G  PAE T  N+++ K+Q+++LG+S DW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVATCAPEYYKWTQWLFLQLYQAGLAYQKEAAVNWDPIDQTVLANEQVDSEGYSWRSGAK  183
            EV T  P+YYKWTQW+F +LY+ GLAY+ E +VNW     T +ANE+V ++G S R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  184  VERKLLRQWFLKITDYAEQLLTDLDKLPGWPDRVKLMQENWIGKSVGAYLEFPIKGSEEK  243
            V RK +RQW LKIT YAE+LL DL+ + +WP+ +K MQ NWIGKS GA + F +K+++  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  244  IAVFTTRPDTVYGVTYVVLAPEHPLTLKVTTPEQKAAVDAFIEEVSNESEIERTAEDKPK  303
            ++VFTTRPDT++G TY VLAPEH+L   +TT++Q  AV  +  + S  S++ RT   K K
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEK  302

Query  304  RGILTGGTAINPFNGQEIPILIADYVLYEYGTGAVMGVPAHDTRDFKFAKEKQLPIKVVI  363
             G+ TG+ AINP NG+E+P+ IADYVL  YGTGA+M+VPAHD RD  FAK+ +L I  V+
Sbjct  303  TGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL  362

Query  364  IPENSDNTNPPLTEAYTDPGIMVNSGIFDGIQSTEGKTAIIEYAEKEGYGKARIQYRLRD  423
               N +++      A+T+ G+ +NS+++DG++ + + + ++E  E EG G+  + YRLRD
Sbjct  363  EGGNVEEA------AFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  424  WLISRQRYWGCPIPVVHCPSCGTVAVPDADLPVKLPENVEF--TGRDASPLAKLEDWINV  481
            WL+SRQRYWG PIP++H     + AVP+++LP+ LP   ++  +G + SPLA++ DW++V
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  482  PCPSCGEPAKRETDTMDTFIDSSWYYLRYTDANNNQEAFNLEKANDWMAIDQYVGGIEHA  541
                 G  ++RET+TM    +SSWYYLRY D++N +   + E  ++W+++D YVGG EHA
Sbjct  477  TRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  542  ILHLLYSRFFTKALRDRGLVNIDEPFKRLLTQGMVQGLTYKNPQTGKYVPSENVIFQDDH  601
            +LHLLY+RF  K L D G+V   EPF++L+ QGM+ G +Y++++ G  V++++V  +D+ 
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSR-GALVATDKVEKRDGS  594

Query  602  YRDKETGEILSFFYEKMSKSKYNGVDPKQVLGKYGADTARMFILFKAPPEKDLEWDDADV  661
            + + ETGE L     KMSKS  N V+P +V+ +YGADT R++ +F +P +  + W + ++
Sbjct  595  FFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGL  654

Query  662  EGQFRFLNRVWRLVANYLENKPKTVKKASELTKEDKD-LRRAIHTAIKEISEDLEGDYQF  720
            EG  +FL+RV RL++            + E+T E+ + L +  + ++K ++E+++ + +F
Sbjct  655  EGSRKFLDRVYRLIT------------TKEITEENSGALDKVYNETVKAVTEQVD-QMKF  701

Query  721  NTAVSELMKLSNALTDAKCLESGVYQEGIETLLILLAPFAPHIAEELWHNL-GYEKSIHL  779
            NTA+++LM     + +A   E  ++ +    ++ L+APFAPH++EELW+ L +   SI  
Sbjct  702  NTAIAQLM----VFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISY  757

Query  780  QSWPTVNPDALVVDEITLVIQIMGKTRGTIQVSATATKDELEKLARESEVGQRYLDGQDV  839
             +WP+ +   LV +++ +V+QI GK ++ + V+   +++EL+ +A  +E  Q  + G+D+
Sbjct  758  VPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDI  817

Query  840  KKVIVVPGKLVNFVI  854
             KVI VP KLVN+VI
Sbjct  818  IKVIAVPNKLVNIVI  832

720) Nos7524_2415 in NC_019684


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  603 bits (2279),  Expect = 1e-173, Method: Compositional matrix adjust.
 Identities = 385/874 (45%), Positives = 581/874 (67%), Gaps = 51/874 (5%)

Query  19   YNAAAIEEKWQQAWAELGLDKTPTDSNQPKFYALSMFPYPSGS-LHMGHVRNYTITDVIA  77
            Y+ +AIE KWQ  WA+    KT TD+++PKFYAL MFPYPSG+ LH+GH   YT TD+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  78   RLKRMQGYRVLHPMGWDAFGLPAENAAIDRGVPPAKWTYQNIAQMRQQLQRLGLSIDWDS  137
            R+KR QG  VLHPMGWDAFGLPAE+ A+D G  PA  T +NIA+ ++Q++ LG+S DWD 
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  138  EVATCSPDYYKWTQWIFLQFLQMGLAYQKEAAVNWDPIDQTVLANEQVDSEGRSWRSGAK  197
            EV T  P+YYKWTQWIF ++ + GLAY+ E +VNW     T +ANE+V ++G S R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  198  VERKLLRQWFLKITDYAEQLLNDLDKLTGWPERVKLMQANWIGKSTGAYLEFPIVGSSEK  257
            V RK +RQW LKIT YAE+LL+DL+ + +WPE +K MQ NWIGKSTGA + F + ++   
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  258  IAVYTTRPDTVFGVSYVVLAPEHPLTKQVTSKAQQATVEAFIHEVTNQSELERTAEDKPK  317
            ++V+TTRPDT+FG +Y VLAPEH+L   +T+  Q  +V  + ++ + +S+L RT   K K
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEK  302

Query  318  RGVPTGGKVVNPFTGEEVPIWIADYVLYEYGTGAVMGVPAHDARDFKFAQRYDLPIDFVI  377
             GV TG+  +NP  G E+P+WIADYVL  YGTGA+M+VPAHD RD  FA++++L      
Sbjct  303  TGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNL------  356

Query  378  ADPKDVAGFDLTPTSDGEEVTQLVQIEYNDAYTEPGILINSGAFTGLNSTDAKQAITKYA  437
                     D+ P  +G +V +        A+TE G+ INS+ + GL+ + A   +    
Sbjct  357  ---------DIIPVLEGGNVEE-------AAFTEDGLHINSDFLDGLDKASAIAKMVEWL  400

Query  438  EENSFGKERVQYRLRDWLISRQRYWGAPIPVIHCPNCGIVPVPDKDLPVQLP--EEVEFT  495
            E ++ G+E V YRLRDWL+SRQRYWG PIP+IH  +    +VP+ +LP+ LP   ++  +
Sbjct  401  EAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPS  460

Query  496  GRGGSPLAQLESWVNVPCPTCGTPAKRETDTMDTFIDSSWYFLRYPDAQNEQQIFELGKT  555
            G G SPLA++  W++V     G  ++RET+TM    +SSWY+LRY D++N +++ +    
Sbjct  461  GTGESPLANVTDWLEVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELL  519

Query  556  NDWMPVDQYVGGIEHAILHLLYSRFFTKVLRDRGLLNFDEPFERLLTQGMVQGLTYMNPN  615
            ++W+PVD YVGG EHA+LHLLY+RF  KVL D G++   EPF++L+ QGM+ G +Y    
Sbjct  520  KQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY----  575

Query  616  KGGKDKWIPSSLVNPNDPR--DPQTGEPLQRLYATMSKSKGNGVAPEDVIAKYGVDTARM  673
            +++++  +++  V+  D    + +TGE L++  A MSKS  N V P+DV+ +YG DT R+
Sbjct  576  RDSRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRV  635

Query  674  FILFKAPPEKDLEWDEADVEGQFRFLNRVWRLVTEYVAAGVCRKQAQLDNLSKPEKELRR  733
            + +F +P +  + W E ++EG  +FL+RV RL+T         K+   +N +     L +
Sbjct  636  YEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITT--------KEITEENSG----ALDK  683

Query  734  AIHTAIQAVTEDLEDEYQFNTAVSELMKLSNAITDANCQNSPIYAEGMRTLVVLLAPFAP  793
              + +++AVTE++ D+ +FNTA+++LM     + +A  ++  ++++  + +V L+APFAP
Sbjct  684  VYNETVKAVTEQV-DQMKFNTAIAQLM----VFVNAANKEDKLFSDYAKGFVQLIAPFAP  738

Query  794  HIADELWH-LLGNKESVHTQSWPSFDPEALVADEVTVVIQINGKKRADIQVPAQADKAAL  852
            H+++ELW+ L ++ ES+   +WPS+D   LV ++V +V+QI+GK +A + V+ +  +  L
Sbjct  739  HLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREEL  798

Query  853  EKFALESEVTQRYIEGKEIKKVIVVPGKLVNFVV  886
            +  AL +E  Q  I GK+I KVI VP KLVN+V+
Sbjct  799  QEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

721) Calkro_1446 in NC_014720


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  603 bits (2277),  Expect = 2e-173, Method: Compositional matrix adjust.
 Identities = 386/854 (46%), Positives = 572/854 (67%), Gaps = 63/854 (7%)

Query  3    YNFKEIEKKWQQKWFSQNKYKVSEDSSKPKYYVLEMFPYPSGK-LHMGHVRNYSIGDVFA  61
            Y+   IE KWQ  W  ++ +K + D+SKPK+Y L+MFPYPSG  LH+GH   Y+  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  62   RFMRLKGYNVLHPMGWDAFGLPAENAAIKHGIHPSDWTWSNIENMKRQLMELGISYDWDR  121
            RF R +G NVLHPMGWDAFGLPAE+ A+  G +P++ T  NI N KRQ+  LG+SYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  122  EVATCHPDYYKWTQWMFLQFYKAGLAYRKRSYVNWCPSCETVLANEQVV-NGRCERCKSL  180
            EV T +P+YYKWTQW+F ++Y  GLAY     VNW     T +ANE+V+ +G  ER    
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  181  VGKKDLEQWFFRITNYAERLLRDIEKLDGWPEKVKIMQKNWIGRSEGTEIEFEIEDLGKK  240
            V +K + QW ++IT YAERLL D+E +D WPE +K MQ+NWIG+S G+++ F + D +K 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  241  IKVFTTRPDTLFGVTYLVLAPEHPLTKEIIAGKPQEKECLEFIEKMQYLNEIERTSTETE  300
            + VFTTRPDTLFG TY VLAPEH+L   I ++  Q     ++  +    +++ RT    E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSD-QAEAVADYKRQASLKSDLARTDLAKE  301

Query  301  KEGRFTGGYAIHPLTGERVPIYIANYVLVDYGTGAVMGVPAHDQRDFEFAKKYNLSIKVV  360
            K G  TG+YAI+P+ G  +P+ IA+YVL  YGTGA+M+VPAHD+RD EFAK++NL I  V
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  361  IKGEGIDIENLQSAYEDEGVLINSGIFDGLNNKEAMKKITQYLEQKGVGRACVTYKLRDW  420
            + G  ++    ++A+ ++G+ INS+++DGL++  A+ K+ + LE  GVG   VTY+LRDW
Sbjct  362  LEGGNVE----EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDW  417

Query  421  LISRQRYWGAPIPIVYCEECGIvpvpeedlpvllpYNVEFKP--TGQSPLSYCEEFVNTT  478
            L+SRQRYWG PIPI+  E+    +VPE +LP++LP   +++P  TG+SPL+   + ++ T
Sbjct  418  LFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT  477

Query  479  CPKCGKPAKRETDTMDTFICSSWYYFRYTDPKNDKKPFEKSLVSYWLPVDQYIGGVEHAI  538
                 K ++RET+TM     SSWYY+RY DP N  K  +  L+  WLPVD Y+GG EHA+
Sbjct  478  REDGVK-GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  539  LHLLYSRFFTKVLYDLGYVPFEEPFKNLLTQGMVL-------------------KDG---  576
            LHLLY+RF  KVLYDLG VP  EPF++L+ QGM+L                   +DG   
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFF  596

Query  577  ------------AKMSKSLGNIVSPEDIVEKYGADTARLFILFAAPPERDLEWSDQGVEG  624
                        AKMSKSL N+V+P+D+VE+YGADT R++ +F +P +  + WS++G+EG
Sbjct  597  HVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEG  656

Query  625  CFRFLNRLWRLYIELKNKLADDSLIGESELDDELRYRLNYTIKKVTEDIAERFNFNTAIS  684
              +FL+R+ RL I  K+   ++S    + LD    Y  N T+K VTE++ ++ +FNTAI+
Sbjct  657  SRKFLDRVYRL-ITTKEITEENS----GALDKV--Y--NETVKAVTEQV-DQMKFNTAIA  706

Query  685  TIMELLNFLYEYKECGKLNKDLIKDTLRNLLILIYPFTPHIACELWEIM-GYGNDIEEVN  743
               +L+ F+    + ++ +  L+ D  + ++ LI PF+PH++ ELW+ + + G+ I  V 
Sbjct  707  ---QLMVFV----NAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVP  759

Query  744  WPQYNEAALVRKNVEIAIQINGKVRSRMNISVDMTEEEVKQAVISDEKLKALLNGKEIVK  803
            WP Y+E+ LV ++VEI +QI+GKV++++ ++ D++ EE+++  +++EK++A + GK+I+K
Sbjct  760  WPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIK  819

Query  804  FVYVKNRLVNIVVK  817
             + V N+LVNIV+K
Sbjct  820  VIAVPNKLVNIVIK  833

722) Syn6312_1305 in NC_019680


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  603 bits (2278),  Expect = 2e-173, Method: Compositional matrix adjust.
 Identities = 384/855 (45%), Positives = 573/855 (68%), Gaps = 29/855 (3%)

Query  5    YQPQEIETKWQQAWADQGLDVTGTEPEKPKFYALSMFPYPSG-NLHMGHVRNYTIPDVIA  63
            Y+   IE KWQ  WAD+    TGT++ KPKFYAL MFPYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RVKRMQGYRVLHPMGWDAFGLPAENAAIERGIPPAEWTEANIAQMKTQLQPLGLSYDWSR  123
            R KR QG  VLHPMGWDAFGLPAE+ A++ G  PAE T  NIA+ K Q+++LG+SYDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCRPDYYRWTQWLFLQFFQAGLAYQKEAAVNWDPIDQTVLANEQVDNEGRSWRSGAI  183
            E+ T  P+YY+WTQW+F ++++ GLAY+ E +VNW     T +ANE+V  +G S R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  184  VERKLLRQWFLKITDYAEALLQDLDTLTDWPERVKLMQANWIGKSTGAYLEFPIVGSEQK  243
            V RK +RQW LKIT YAE LL+DL+ + DWPE +K MQ NWIGKSTGA + F + ++++ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  244  IAVFTTRPDTVYGVTYVVLAPEHPLTQAVTTNENQAQVAEFIKSISHESELERTAEDKPK  303
            ++VFTTRPDT++G TY VLAPEH+L +A+TT+++   VA++ +  S  S+L RT   K K
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEK  302

Query  304  RGLATGGKALNPFTGESIPIWIADYVLVEYGTGAVMGVPAHDQRDYQFAQQNQLPIKTVI  363
             G+ TG+ A+NP  G  +P+WIADYVL  YGTGA+M+VPAHD+RD +FA+Q +L I  V+
Sbjct  303  TGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL  362

Query  364  IPANPEMVKLDQAYTEPGILINSGDFDGLESQTAKTKIIEFAESQGWGKARIQYRLRDWL  423
              +N E    + A+TE G+ INS+ +DGL+  +A +K++E  E++G G+  + YRLRDWL
Sbjct  363  EGGNVE----EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWL  418

Query  424  ISRQRYWGVPIPIIH--CPDCGavpvpdadlpvllpENVEFTGRGASPLAQLEDWVNVPC  481
            +SRQRYWG PIPIIH       AVP ++  L + +  ++  +G G SPLA++ DW++V  
Sbjct  419  FSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTR  478

Query  482  PTCGKPAQRETDTMDTFIDSSWYFLRFADAQNDQAPFDPKVVNDWLPVDQYVGGIEHAIL  541
                K ++RET+TM    +SSWY+LR+ D++N +   D  ++++WLPVD YVGG EHA+L
Sbjct  479  EDGVK-GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVL  537

Query  542  HLLYSRFFTKVLKDRGLINFSEPFQRLLTQGMVQGKTYKNPQTGKYVIPSQVKDPNNP-V  600
            HLLY+RF  KVL D G++   EPFQ+L+ QGM+ G +Y++++ G  V   +V   + +  
Sbjct  538  HLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSR-GALVATDKVEKRDGSFF  596

Query  601  DPDSGIALDVVYEKMSKSKHNGVAPGDVIEKYGADTARMFILFKAPPEKDLEWDDADVEG  660
            + ++G  L+    KMSKS  N V P+DV+E+YGADT R++ +F +P +  + W + ++EG
Sbjct  597  HVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEG  656

Query  661  QFRFLNRVWRLVTGYVEKNPEVKSTHAELSPDEKKLRRAIHTAIKEVSEDFEDYQFNTAI  720
              +FL+RV RL+T       E+   ++        L +  + ++K V+E+ ++ +FNTAI
Sbjct  657  SRKFLDRVYRLIT-----TKEITEENSG------ALDKVYNETVKAVTEQVDQMKFNTAI  705

Query  721  SELMKLSNALGDAADLITSSTYQEGIKTLLLLLSPFAPHITEELWEQLPKREHSTSIHLQ  780
            ++LM + NA      L     + +  K ++ L++PFAPH+ EELW+ L     + SI   
Sbjct  706  AQLMVFVNAANKEDKL-----FSDYAKGFVQLIAPFAPHLGEELWQALT--ASGESISYV  758

Query  781  AWPKVDPTALVADEISLVIQIMGKTRGVIQVPAQAEANDLETYARNSEVGERYLAGQTVK  840
            +WP  D + LV +++ +V+QI GK ++ + V+ +   ++L+  A  +E  +  +AG+ + 
Sbjct  759  PWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDII  818

Query  841  KVIVVPGKLINFVLQ  855
            KVI VP KL+N+V++
Sbjct  819  KVIAVPNKLVNIVIK  833

723) leuS in NC_013216


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  603 bits (2278),  Expect = 2e-173, Method: Compositional matrix adjust.
 Identities = 375/863 (44%), Positives = 569/863 (66%), Gaps = 72/863 (8%)

Query  5    YNFEEIESKWQKIWAGNDQYATADFSERPEYYCLEMFPYPSG-NLHMGHVRNYSIGDVVA  63
            Y+   IE+KWQ +WA+N+ + T+  + +P +Y L+MFPYPSG  LH+GH   Y+  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RFKSMRGFDVLHPMGWDAFGLPAENAAIKHGNMHPADWTFANIDNMRTQLKQLGLSYDWN  123
            RFK  +G +VLHPMGWDAFGLPAE+ A+  GN +PA+ T  NI N + Q++ LG+SYDW+
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGN-DPAEFTAENIANFKRQINALGFSYDWD  122

Query  124  REVATCHPGYYKWTQWLFLQLYHHNLAYKKYAAVNWCPSCATVLANEQVKEDG-CERCGT  182
            REV T +P YYKWTQW+F +LY+  LAY    +VNW    +T +ANE+V  DG  ER G 
Sbjct  123  REVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGY  182

Query  183  TVEKKNLDQWFFKITDYAERLLADLDKLPGWPEKVKIMQRNWIGRSEGAELTFQVKDSQE  242
             V +K + QW +KIT YAERLL DL+ + +WPE +K MQRNWIG+S GA++TF+VKD++ 
Sbjct  183  PVVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDK  241

Query  243  SITVYTTRPDTVFGVSCMVLAPEHPLVEKLIAGTEQERQVKDFVAKMRALSDADRTSDEA  302
             +TV+TTRPDT+FG +  VLAPEH+LV+  I+ ++Q   V D+  +    SD  RT    
Sbjct  242  DFTVFTTRPDTLFGATYAVLAPEHALVDA-ITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  303  EKIGVLTGACCINPFNGDQVPIMVANYVLLEYGTGCVMGVPAHDQRDFEFAAKYKLPVKV  362
            EK GV TG+  INP NG ++P+ +A+YVL  YGTG +M+VPAHD+RD EFA +++L +  
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  363  VIQPAGESLDPAKMQRAYVDEGFLVNSGQFDGMGSSDAIRAITAFAEEKGIGSGKVNFRL  422
            V++  G +++ A    A+ ++G+ +NS+ +DG++ + AI  +    E  G+G+ +V +RL
Sbjct  361  VLE--GGNVEEA----AFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRL  414

Query  423  RDWLISRQRYWGVPIPIIYCEQCGNVPVPEKDLPVMLPYDVQFKPAGR--SPLADREEFV  480
            RDWL+SRQRYWG PIPII  E+  + +VPE +LP++LP   +++P+G   SPLA+  + +
Sbjct  415  RDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWL  474

Query  481  HTVCPSCGGPARRETDTMDTFVCSSWYFYRYTSPRDEARAWDKAKADRWMPVDQYIGGVE  540
            + V    G  +RRET+TM     SSWY+ RY  P++  +  D     +W+PVD Y+GG E
Sbjct  475  E-VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAE  533

Query  541  HAILHLLYARFFAKVFYDLKLISAEEPFENLLTQGMVL-------------------KEG  581
            HA+LHLLYARF  KV+YDL ++++ EPF++L+ QGM+L                   ++G
Sbjct  534  HAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDG  593

Query  582  ---------------AKMSKSKGNVVSPEEIIKRYGADTARLFILFAAPPERDLEWSDQG  626
                           AKMSKS  NVV+P++++ +YGADT R++ +F +P +  + WS++G
Sbjct  594  SFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEG  653

Query  627  VEGSYRFLNRVWRLVTPLAADLLKAPVKPEGEVSGVHKEMRRLSHYTIKKVTEDIEERFN  686
            +EGS +FL+RV RL+T              G +  V +E       T+K VTE++++  +
Sbjct  654  LEGSRKFLDRVYRLITTKE-----ITEENSGALDKVYNE-------TVKAVTEQVDQ-MK  700

Query  687  FNTAVSAIMELVNGLYHYRDKLAEPDRDPAVMREAIEALLVLLSPFAPHLAEELWSGI-G  745
            FNTA++ +M +VN+          ++++  +  +   +++ L++PFAPHL+EELW ++ +
Sbjct  701  FNTAIAQLMVFVNA----------ANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTA  750

Query  746  HKDSVHAQPWPVYEPEALVEDEIEIVVQINGKVRDRLSVPANLSAASMQEYVLQQPKIIS  805
              +S+   PWP Y+   LVE+++EIVVQI+GKV+ +L V+ +LS   +QE  L + K+ +
Sbjct  751  SGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQA  810

Query  806  LTAGKEVKKIIPVPGKLVNIVVK  828
              AGK++ K+I+VP KLVNIV+K
Sbjct  811  EIAGKDIIKVIAVPNKLVNIVIK  833

724) leuS in NC_013161


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  602 bits (2276),  Expect = 2e-173, Method: Compositional matrix adjust.
 Identities = 379/855 (45%), Positives = 582/855 (69%), Gaps = 31/855 (3%)

Query  5    YNAAAIEQKWQQDWVKQGLDKTPENSNKPKFYALSMFPYPSG-NLHMGHVRNYVITDVIA  63
            Y+ +AIE KWQ  W  +   KT  +++KPKFYAL MFPYPSG  LH+GH   Y  TD+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RLKRLQGYRVLHPMGWDAFGLPAENAAIDRGIPPAEWTYKNMSQMKQQLQTLGLSIDWER  123
            R+KR QG  VLHPMGWDAFGLPAE+ A+D G  PAE T  N+++ K+Q+++LG+S DW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVATCAPEYYKWTQWLFLQLYQAGLAYQKEAAVNWDPIDQTVLANEQVDSEGYSWRSGAK  183
            EV T  P+YYKWTQW+F +LY+ GLAY+ E +VNW     T +ANE+V ++G S R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  184  VERKLLRQWFLKITDYAEQLLTDLDKLSGWPDRVKLMQENWIGKSVGAYLEFPIKGSEEK  243
            V RK +RQW LKIT YAE+LL DL+ + +WP+ +K MQ NWIGKS GA + F +K+++  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  244  IAVFTTRPDTVYGVTYVVLAPEHPLTLKVTTPEQKAAVDAFIEEVSNESEIERTAEDKPK  303
            ++VFTTRPDT++G TY VLAPEH+L   +TT++Q  AV  +  + S  S++ RT   K K
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEK  302

Query  304  RGILTGGTAINPFNGQEIPILIADYVLYEYGTGAVMGVPAHDTRDFKFAKEKQLPIKVVI  363
             G+ TG+ AINP NG+E+P+ IADYVL  YGTGA+M+VPAHD RD  FAK+ +L I  V+
Sbjct  303  TGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL  362

Query  364  IPENSDNTNPPLTEAYTDPGIMVNSGIFDGIQSTEGKTAIIEYAEKEGYGKARIQYRLRD  423
               N +++      A+T+ G+ +NS+++DG++ + + + ++E  E EG G+  + YRLRD
Sbjct  363  EGGNVEEA------AFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  424  WLISRQRYWGCPIPVVHCPSCGTVAVPDADLPVKLPENVEF--TGRGASPLAKLEDWINV  481
            WL+SRQRYWG PIP++H     + AVP+++LP+ LP   ++  +G G SPLA++ DW++V
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  482  PCPSCGEPAKRETDTMDTFIDSSWYYLRYTDANNNQEAFNLEKANDWMAIDQYVGGIEHA  541
                 G  ++RET+TM    +SSWYYLRY D++N +   + E  ++W+++D YVGG EHA
Sbjct  477  TRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  542  ILHLLYSRFFTKALRDRGLVNIDEPFKRLLTQGMVQGLTYKNPQTGKYVPSENVIFQDDH  601
            +LHLLY+RF  K L D G+V   EPF++L+ QGM+ G +Y++++ G  V++++V  +D+ 
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSR-GALVATDKVEKRDGS  594

Query  602  YRDKETGEILSFFYEKMSKSKYNGVDPKQVLGKYGADTARMFILFKAPPEKDLEWDDADV  661
            + + ETGE L     KMSKS  N V+P +V+ +YGADT R++ +F +P +  + W + ++
Sbjct  595  FFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGL  654

Query  662  EGQFRFLNRVWRLVANYLENKPKTVKKASELTKEEKD-LRRAIHTAIKEISEDLEGDYQF  720
            EG  +FL+RV RL++            + E+T E+ + L +  + ++K ++E+++ + +F
Sbjct  655  EGSRKFLDRVYRLIT------------TKEITEENSGALDKVYNETVKAVTEQVD-QMKF  701

Query  721  NTAVSELMKLSNALTDAKCLESGVYQEGIETLLILLAPFAPHIAEELWHNL-GYEKLIHL  779
            NTA+++LM     + +A   E  ++ +    ++ L+APFAPH++EELW+ L +    I  
Sbjct  702  NTAIAQLM----VFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISY  757

Query  780  QSWPTVNPDALVVDEITLVIQIMGKTRGTIQVSATATKDELEKLARESEVGQRYLDGQDV  839
             +WP+ +   LV +++ +V+QI GK ++ + V+   +++EL+ +A  +E  Q  + G+D+
Sbjct  758  VPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDI  817

Query  840  KKVIVVPGKLVNFVI  854
             KVI VP KLVN+VI
Sbjct  818  IKVIAVPNKLVNIVI  832

725) leuS in NC_012034


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  602 bits (2274),  Expect = 3e-173, Method: Compositional matrix adjust.
 Identities = 381/854 (45%), Positives = 569/854 (67%), Gaps = 63/854 (7%)

Query  3    YNFKEIEKKWQQKWFSQNKYKVSEDSSKPKYYVLEMFPYPSGK-LHMGHVRNYSIGDVFA  61
            Y+   IE KWQ  W  ++ +K + D+SKPK+Y L+MFPYPSG  LH+GH   Y+  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  62   RFMRLKGYNVLHPMGWDAFGLPAENAAIKHGIHPSDWTWSNIENMKRQLMELGISYDWDR  121
            RF R +G NVLHPMGWDAFGLPAE+ A+  G +P++ T  NI N KRQ+  LG+SYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  122  EVATCHPDYYKWTQWMFLQFYKAGLAYRKRSYVNWCPSCETVLANEQVV-NGRCERCKSL  180
            EV T +P+YYKWTQW+F ++Y  GLAY     VNW     T +ANE+V+ +G  ER    
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  181  VGKKDLEQWFFRITNYAERLLRDIEKLDGWPEKVKIMQKNWIGRSEGAEIEFEIEGLGKK  240
            V +K + QW ++IT YAERLL D+E +D WPE +K MQ+NWIG+S GA++ F + + +K 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  241  IKVFTTRPDTLFGVTYLVLAPEHPLTKEIIAGKPQEKECLEFIEKMQYLNEIERTSTETE  300
            + VFTTRPDTLFG TY VLAPEH+L   I ++  Q     ++  +    +++ RT    E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSD-QAEAVADYKRQASLKSDLARTDLAKE  301

Query  301  KEGRFTGGYAIHPLTGERVPIYIANYVLVDYGTGAVMGVPAHDQRDFEFAKKYNLSIKVV  360
            K G  TG+YAI+P+ G  +P+ IA+YVL  YGTGA+M+VPAHD+RD EFAK++NL I  V
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  361  IKGEGIDIENLQSAYEDEGVLINSGIFNGLNNKEAMKKITQYLEQKGVGRACVTYKLRDW  420
            + G  ++    ++A+ ++G+ INS++++GL++  A+ K+ + LE  GVG   VTY+LRDW
Sbjct  362  LEGGNVE----EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDW  417

Query  421  LISRQRYWGAPIPIVYCEECGIvpvpeedlpvllpYNVEFKP--TGQSPLSYCEEFVNTT  478
            L+SRQRYWG PIPI+  E+    +VPE +LP++LP   +++P  TG+SPL+   + ++ T
Sbjct  418  LFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT  477

Query  479  CPKCGKPAKRETDTMDTFICSSWYYFRYTDPKNDKKPFEKSLVSYWLPVDQYIGGVEHAI  538
                 K ++RET+TM     SSWYY+RY DP N  K  +  L+  WLPVD Y+GG EHA+
Sbjct  478  REDGVK-GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  539  LHLLYSRFFTKVLYDLGYVPFEEPFKNLLTQGMVL-------------------KDG---  576
            LHLLY+RF  KVLYDLG VP  EPF++L+ QGM+L                   +DG   
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFF  596

Query  577  ------------AKMSKSLGNIVSPEDIVERYGADTARLFILFAAPPERDLEWSDQGVEG  624
                        AKMSKSL N+V+P+D+VE+YGADT R++ +F +P +  + WS++G+EG
Sbjct  597  HVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEG  656

Query  625  CFRFLNRLWRLYIELKDKLADDNLIGESELDDELRYRLNYTIKKVTEDIAERFNFNTAIS  684
              +FL+R+ RL       ++  ++  E+    +  Y  N T+K VTE++ ++ +FNTAI+
Sbjct  657  SRKFLDRVYRL-------ITTKEITEENSGALDKVY--NETVKAVTEQV-DQMKFNTAIA  706

Query  685  TIMELLNFLYEYKECGKLNKDLIKDTLRNLLILIYPFTPHIACELWEIM-GYGNDIEEVN  743
               +L+ F+    + ++ +  L+ D  + ++ LI PF+PH++ ELW+ + + G+ I  V 
Sbjct  707  ---QLMVFV----NAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVP  759

Query  744  WPQYNEAALVRKNVEIAIQINGKVRSRMNISVDMTEEEVKQAVICDEKLKALLNGKEIVK  803
            WP Y+E+ LV ++VEI +QI+GKV++++ ++ D++ EE+++  + +EK++A + GK+I+K
Sbjct  760  WPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIK  819

Query  804  FVYVKNRLVNIVVK  817
             + V N+LVNIV+K
Sbjct  820  VIAVPNKLVNIVIK  833

726) Calhy_1471 in NC_014652


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  602 bits (2275),  Expect = 3e-173, Method: Compositional matrix adjust.
 Identities = 382/854 (45%), Positives = 569/854 (67%), Gaps = 63/854 (7%)

Query  3    YNFKEIEKKWQQKWFSQNKYKVSEDSPKPKYYVLEMFPYPSGK-LHMGHVRNYSIGDVFA  61
            Y+   IE KWQ  W  ++ +K + D++KPK+Y L+MFPYPSG  LH+GH   Y+  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  62   RFMRLKGYNVLHPMGWDAFGLPAENAAIKHGIHPSDWTWSNIENMKRQLMELGISYDWDR  121
            RF R +G NVLHPMGWDAFGLPAE+ A+  G +P++ T  NI N KRQ+  LG+SYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  122  EVATCHPDYYKWTQWMFLQFYKAGLAYRKRSYVNWCPSCETVLANEQVV-NGRCERCKSL  180
            EV T +P+YYKWTQW+F ++Y  GLAY     VNW     T +ANE+V+ +G  ER    
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  181  VGKKDLEQWFFRITNYAERLLRDIEKLDGWPEKVKIMQKNWIGRSEGAEIEFEIEGLNKK  240
            V +K + QW ++IT YAERLL D+E +D WPE +K MQ+NWIG+S GA++ F + + +K 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  241  IKVFTTRPDTLFGVTYLVLAPEHPLTKEIIAGKPQERECLEFIEKMQYLNEIERTSTETE  300
            + VFTTRPDTLFG TY VLAPEH+L   I ++   E    ++  +    +++ RT    E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAE-AVADYKRQASLKSDLARTDLAKE  301

Query  301  KEGRFTGGYAIHPLTGERVPIYIANYVLVDYGTGAVMGVPAHDQRDFEFAKKYNLPIKVV  360
            K G  TG+YAI+P+ G  +P+ IA+YVL  YGTGA+M+VPAHD+RD EFAK++NL I  V
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  361  IKGEGVDIENFQNAYEDEGVLINSGIFDGLKNTEAMKKITQYLEQKGVGRACVTYKLRDW  420
            + G  V+    + A+ ++G+ INS+++DGL ++ A+ K+ + LE  GVG   VTY+LRDW
Sbjct  362  LEGGNVE----EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDW  417

Query  421  LISRQRYWGAPIPIVYCDECGvvpvpeedlpvllpYNVEFKP--TGQSPLSYCEEFVNTT  478
            L+SRQRYWG PIPI+  ++    +VPE +LP++LP   +++P  TG+SPL+   + ++ T
Sbjct  418  LFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT  477

Query  479  CPKCGKPAKRETDTMDTFICSSWYYFRYTDPKNDQKPFEKSLVSYWLPVDQYIGGVEHAI  538
                 K ++RET+TM     SSWYY+RY DP N +K  +  L+  WLPVD Y+GG EHA+
Sbjct  478  REDGVK-GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  539  LHLLYSRFFTKVLYDLGYVPFEEPFKNLLTQGMVL-------------------KDG---  576
            LHLLY+RF  KVLYDLG VP  EPF++L+ QGM+L                   +DG   
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFF  596

Query  577  ------------AKMSKSLGNIVSPEDIVEKYGADTARLFILFAAPPERDLEWSDQGVEG  624
                        AKMSKSL N+V+P+D+VE+YGADT R++ +F +P +  + WS++G+EG
Sbjct  597  HVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEG  656

Query  625  CFRFLNRLWRLYIELKNKLADDNLIGESELDDELRYRLNYTIKKVTEDIGERFNFNTAIS  684
              +FL+R+ RL       ++  ++  E+    +  Y  N T+K VTE++ ++ +FNTAI+
Sbjct  657  SRKFLDRVYRL-------ITTKEITEENSGALDKVY--NETVKAVTEQV-DQMKFNTAIA  706

Query  685  TIMELLNFLYEYKENGKLNKDLIIDTLRNLLILIYPFTPHIACELWEIM-GFGEDIEEVS  743
               +L+ F+   + ++KL  D      + ++ LI PF+PH++ ELW+ + + GE I  V+
Sbjct  707  ---QLMVFVNAANKEDKLFSDYA----KGFVQLIAPFAPHLGEELWQALTASGESISYVP  759

Query  744  WPQYDEAALVRKNVEIAIQINGKVRSRMNISVDMTEEEVKQAVINDQKLKALLNGKEIVK  803
            WP YDE+ LV ++VEI +QI+GKV++++ ++ D++ EE+++  + ++K++A + GK+I+K
Sbjct  760  WPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIK  819

Query  804  FVYVKNRLVNIVVR  817
             + V N+LVNIV++
Sbjct  820  VIAVPNKLVNIVIK  833

727) Csac_1819 in NC_009437


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  602 bits (2273),  Expect = 4e-173, Method: Compositional matrix adjust.
 Identities = 394/854 (47%), Positives = 570/854 (67%), Gaps = 63/854 (7%)

Query  3    YNFREIEKKWQQKWFSQNKYKVTEDSPKPKYYVLEMFPYPSGK-LHMGHVRNYSIGDVFA  61
            Y+   IE KWQ  W  ++ +K   D++KPK+Y L+MFPYPSG  LH+GH   Y+  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  62   RFMRLKGYNVLHPMGWDAFGLPAENAAIKHGIHPSDWTWSNIENMKRQLKELGISYDWDR  121
            RF R +G NVLHPMGWDAFGLPAE+ A+  G +P++ T  NI N KRQ++ LG+SYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  122  EVATCHPDYYKWTQWMFLQFYKAGLAYRKRSYVNWCPSCETVLANEQVV-NGRCERCKSL  180
            EV T +P+YYKWTQW+F ++Y  GLAY     VNW     T +ANE+V+ +G  ER    
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  181  VGKKDLEQWFFRITKYAERLLRDIDKLDGWPEKVKIMQKNWIGRSEGAEIEFEIDGLGKR  240
            V +K + QW ++IT YAERLL D++ +D WPE +K MQ+NWIG+S GA++ F + + +K 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  241  IKVFTTRPDTLFGVTYLVLAPEHPLTKEIIAGKPQEKECLEFIEKMQYLNEIERTSTETE  300
            + VFTTRPDTLFG TY VLAPEH+L  + I+   Q     ++  +    +++ RT    E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALV-DAITTSDQAEAVADYKRQASLKSDLARTDLAKE  301

Query  301  KEGRFTGGYAIHPLTGKKVPIYIANYVLVDYGTGAVMGVPAHDQRDFEFAKKYNLPIKVV  360
            K G  TG+YAI+P+ GK +P+ IA+YVL  YGTGA+M+VPAHD+RD EFAK++NL I  V
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  361  IKGDGVDIQNLQSAYEGEGVLINSGEFNGLKNTEAMKKITEYLEKNGYGKACVTYKLRDW  420
            + G+ V+    ++A+  +G+ INS+ ++GL ++ A+ K+ E LE +G G+  VTY+LRDW
Sbjct  362  LEGGNVE----EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDW  417

Query  421  LISRQRYWGAPIPIVYCDDCGIvpvpeeelpvllpYNVEFKP--TGQSPLAYCEEFVNTT  478
            L+SRQRYWG PIPI+  +D    +VPE ELP++LP   +++P  TG+SPLA   + ++ T
Sbjct  418  LFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT  477

Query  479  CPKCGKPARRETDTMDTFICSSWYYFRYTDPKNSEKPFEKSLVDYWLPVDQYIGGVEHAI  538
                 K +RRET+TM     SSWYY+RY DP N+EK  +  L+  WLPVD Y+GG EHA+
Sbjct  478  REDGVK-GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  539  LHLLYSRFFTKVLYDLGYISFEEPFKNLLTQGMVL-------------------KDG---  576
            LHLLY+RF  KVLYDLG ++  EPF++L+ QGM+L                   +DG   
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFF  596

Query  577  ------------AKMSKSLGNIVSPEEIVEKYGADTARLFILFAAPPERDLEWSDQGVEG  624
                        AKMSKSL N+V+P+++VE+YGADT R++ +F +P +  + WS++G+EG
Sbjct  597  HVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEG  656

Query  625  CFRFLNRLWRLYIELKDKLSDSSLPGQSELDDELNYRLNYTIKKVTEDIGERFNFNTAIS  684
              +FL+R+ RL I  K+   ++S        + L+   N T+K VTE++ ++ +FNTAI+
Sbjct  657  SRKFLDRVYRL-ITTKEITEENS--------GALDKVYNETVKAVTEQV-DQMKFNTAIA  706

Query  685  SIMELLNFLYDYKEKGSLNRELILKTLKNFLILIYPFTPHIACELWEIMGFEGD-IEDVS  743
               +L+ F+   +  + L  +      K F+ LI PF+PH++ ELW+ +   G+ I  V+
Sbjct  707  ---QLMVFVNAANKEDKLFSDYA----KGFVQLIAPFAPHLGEELWQALTASGESISYVP  759

Query  744  WPEYDESALVRKNVEIAVQINGKVRARFDVPVDISEEELKQKIMNNEKIKTLLEGKEIVK  803
            WP YDES LV ++VEI VQI+GKV+A++ V+ D+S EEL++  + NEK+++ + GK+I+K
Sbjct  760  WPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIK  819

Query  804  FIYVKNRLVNIVIK  817
             I V N+LVNIVIK
Sbjct  820  VIAVPNKLVNIVIK  833

728) Calow_1045 in NC_014657


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  602 bits (2274),  Expect = 4e-173, Method: Compositional matrix adjust.
 Identities = 378/854 (45%), Positives = 572/854 (67%), Gaps = 63/854 (7%)

Query  3    YNFKEIEKKWQQKWFSQNKYKVSEDSPKPKYYVLEMFPYPSGK-LHMGHVRNYSIGDVFA  61
            Y+   IE KWQ  W  ++ +K + D++KPK+Y L+MFPYPSG  LH+GH   Y+  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  62   RFMRLKGYNVLHPMGWDAFGLPAENAAIKHGIHPSDWTWSNIQNMKRQLMELGISYDWDR  121
            RF R +G NVLHPMGWDAFGLPAE+ A+  G +P++ T  NI N KRQ+  LG+SYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  122  EVATCHPDYYKWTQWMFLQFYKAGLAYRKRSYVNWCPSCETVLANEQVV-NGRCERCKSL  180
            EV T +P+YYKWTQW+F ++Y  GLAY     VNW     T +ANE+V+ +G  ER    
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  181  VGKKDLEQWFFRITNYAERLLRDIEKLDGWPEKVKIMQKNWIGRSEGAEIEFEIEGLGKK  240
            V +K + QW ++IT YAERLL D+E +D WPE +K MQ+NWIG+S GA++ F + + +K 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  241  IKVFTTRPDTLFGVTYLVLAPEHPLTKEIIAGKPQEKECLEFIEKMQYLNEIERTSTEIE  300
            + VFTTRPDTLFG TY VLAPEH+L   I ++  Q     ++  +    +++ RT    E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSD-QAEAVADYKRQASLKSDLARTDLAKE  301

Query  301  KEGRFTGGYAIHPLTGERVPIYIANYVLVDYGTGAVMGVPAHDQRDFEFAKKYNLPIKVV  360
            K G  TG+YAI+P+ G  +P+ IA+YVL  YGTGA+M+VPAHD+RD EFAK++NL I  V
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  361  IKGEGVDIENLQSAYEDEGVLINSGIFDGLKNTDAMKKITQYLEQKGVGRACVTYKLRDW  420
            + G  V+    ++A+ ++G+ INS+++DGL ++ A+ K+ + LE  GVG   VTY+LRDW
Sbjct  362  LEGGNVE----EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDW  417

Query  421  LISRQRYWGAPIPIVYCDECGIvpvpeedlpvllpYNVEFKP--TGQSPLSYCEEFVNTT  478
            L+SRQRYWG PIPI+  ++    +VPE +LP++LP   +++P  TG+SPL+   + ++ T
Sbjct  418  LFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT  477

Query  479  CPKCGRPAKRETDTMDTFICSSWYYFRYTDPKNDQKPFEKSLVSYWLPVDQYIGGVEHAI  538
                 + ++RET+TM     SSWYY+RY DP N +K  +  L+  WLPVD Y+GG EHA+
Sbjct  478  REDGVK-GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  539  LHLLYSRFFTKVLYDLGYVPFEEPFKNLLTQGMVL-------------------KDG---  576
            LHLLY+RF  KVLYDLG VP  EPF++L+ QGM+L                   +DG   
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFF  596

Query  577  ------------AKMSKSLGNIVSPEDIIEKYGADTARLFILFAAPPERDLEWSDQGVEG  624
                        AKMSKSL N+V+P+D++E+YGADT R++ +F +P +  + WS++G+EG
Sbjct  597  HVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEG  656

Query  625  CFRFLNRLWRLYIELKNKLADDNLVGESELDDELRYRLNYTIKKVTEDIGERFNFNTAIS  684
              +FL+R+ RL       ++  ++  E+    +  Y  N T+K VTE++ ++ +FNTAI+
Sbjct  657  SRKFLDRVYRL-------ITTKEITEENSGALDKVY--NETVKAVTEQV-DQMKFNTAIA  706

Query  685  TIMELLNFLYEYKESGKLNKDLIIDTLRNLLILIYPFTPHIACELWEVM-GFGEDIEEVS  743
               +L+ F+    ++++ +  L+ D  + ++ LI PF+PH++ ELW+ + + GE I  V+
Sbjct  707  ---QLMVFV----NAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVP  759

Query  744  WPQYDEAALVRKNVEIAIQVNGKVRSRMNISVDMTEDEVKQAVLNDQKLKSLLDGKEIVK  803
            WP YDE+ LV ++VEI +Q++GKV++++ ++ D++ +E+++  L ++K+++ + GK+I+K
Sbjct  760  WPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIK  819

Query  804  FVYVKNRLVNIVVK  817
             + V N+LVNIV+K
Sbjct  820  VIAVPNKLVNIVIK  833

729) leuS in NC_021081


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  601 bits (2272),  Expect = 5e-173, Method: Compositional matrix adjust.
 Identities = 407/874 (47%), Positives = 571/874 (66%), Gaps = 50/874 (5%)

Query  7    YNPHELEPKWQQYWEKIGLLKATEGKAGKKAYILVMFPYPSG-DLHMGHLKNYTMGDALA  65
            Y+   +EPKWQ +W     +K+  + +  K Y L MFPYPSG +LH+GH   YT  D L+
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  66   RFRVQQGYSVLHPFGWDAFGLPAENAALKFGVSPADWTFGNIKQSKESLALMGIRYDWSR  125
            RF+  QG +VLHP GWDAFGLPAE+ A+  G  PA+ T  NI + K  +  +G+ YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  126  EVTTCLPEYYKWNQWIFLKMYEKGLVYRKKSLVNWDPVEQSVLANEQVI-DGRGWRSGAL  184
            EV T  P+YYKW QWIF K+YEKGL Y     VNW     + +ANE+V+ DG + R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  185  VEKRELEQWYLKITDYAERLLNDLDKLPRWPEKVKAMQRAWIGKSQGAEFDFQVKGHPAK  244
            V ++ + QW LKIT YAERLL+DL+ +  WPE +K MQR WIGKS GA+  F+VK+    
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  245  IRVFSTRPDTIFGATFMVLAPEHELVPLITTPEQKaaveayvaaaRMKSEVERQMEDREK  304
            + VF+TRPDT+FGAT+ VLAPEH LV  ITT++Q  AV  Y   A +KS++ R    +EK
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEK  302

Query  305  TGVFTGAYAINPANGKEIPIWIADYVLAGYGTGAIMAVPGQDERDWEFAEKFGLEIIRTV  364
            TGV TG+YAINP NGKE+P+WIADYVLA+YGTGAIMAVP++DERDWEFA +F L+II  +
Sbjct  303  TGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL  362

Query  365  EPPAGWQGKAYTEDGPAINSGFLNGLYVEEAKKKIIEWMEEKGIGEGKVNYRLRDWLISR  424
            E     +  A+TEDG  INS+FL+GL    A  K++EW+E  G+G+ +V YRLRDWL+SR
Sbjct  363  EGGNV-EEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSR  421

Query  425  QRYWGTPIPMIHCDSCGIVPVPYEQLPVVLPTLKDVEDIRPKGK--SPLAAHPEFYECTC  482
            QRYWG PIP+IH +     +VP  +LP+VLP  K   DIRP G   SPLA   +  E T 
Sbjct  422  QRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTK---DIRPSGTGESPLANVTDWLEVTR  478

Query  483  PKCGGPARRdtdtmdtffdSSWYFLRYTDAQNPQAPFDPEKANFWMPVDQYIGGIEHAIL  542
               G  +RR+T+TM    +SSWY+LRY D++N +   D E  + W+PVD Y+GG EHA+L
Sbjct  479  ED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVL  537

Query  543  HLLYSRFFTKFLHDLGLVEAEEPFEGLFTQGMVMGWTNVGEVEVREGRIYFLDDARRSKL  602
            HLLY+RF  K L DLG+V + EPF+ LF QGM++G         R++R  ++   +  K 
Sbjct  538  HLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILG------TSYRDSRGALVATDKVEK-  590

Query  603  ELEQGLTLEEAQKSGAELREEGGKTYFWKPAVMSKSLGNGVMVGPFVKEQGADIARVTIL  662
                        + G+ ++ E G      PA MSKSL N V  +  V + GAD  RV  +
Sbjct  591  ------------RDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEM  638

Query  663  FAAPPENEMIWTEEGVQGAWRYLNRVYRLVAEQRVELKAQPDLLEPATLEGPHKALYQKL  722
            F +P +  + W+EEG++G++++L+RVYRL++ + +               G+   +Y   
Sbjct  639  FMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEI----------TEENSGALDKVY---  685

Query  723  HQTIKKVTEDLEALRFNTAIAALMELLNALGDYRKEHGVTPVYREAVLRYIQMLAPFAPH  782
            ++T+K VTE+++ ++FNTAIA LM ++NA     KE+ + + Y  +   ++Q++APFAPH
Sbjct  686  NETVKAVTEQVDQMKFNTAIAQLMVFVNAAN---KEDKLFSDYAKG---FVQLIAPFAPH  739

Query  783  LAEELWHEFY--DDSVFKAPWPRLDESALVADSFELVVQVNGKLRGKTTVSTQASEEEIK  840
            L+EELW+ +   ++S+   PWP  DES LV +  E+VVQ++GK+++K  V+ + S EE++
Sbjct  740  LGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQ  799

Query  841  RLARTLPNVQQHIAGKEVVKEIYVPGKLLNIVVK  874
             +A +  +VQ +IAGK+++K I VP KL+NIV+K
Sbjct  800  EVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

730) Mrub_1074 in NC_013946


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  601 bits (2272),  Expect = 5e-173, Method: Compositional matrix adjust.
 Identities = 407/874 (47%), Positives = 571/874 (66%), Gaps = 50/874 (5%)

Query  7    YNPHELEPKWQQYWEKIGLLKATEGKAGKKAYILVMFPYPSG-DLHMGHLKNYTMGDALA  65
            Y+   +EPKWQ +W     +K+  + +  K Y L MFPYPSG +LH+GH   YT  D L+
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  66   RFRVQQGYSVLHPFGWDAFGLPAENAALKFGVSPADWTFGNIKQSKESLALMGIRYDWSR  125
            RF+  QG +VLHP GWDAFGLPAE+ A+  G  PA+ T  NI + K  +  +G+ YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  126  EVTTCLPEYYKWNQWIFLKMYEKGLVYRKKSLVNWDPVEQSVLANEQVI-DGRGWRSGAL  184
            EV T  P+YYKW QWIF K+YEKGL Y     VNW     + +ANE+V+ DG + R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  185  VEKRELEQWYLKITDYAERLLNDLDKLPRWPEKVKAMQRAWIGKSQGAEFDFQVKGHPAK  244
            V ++ + QW LKIT YAERLL+DL+ +  WPE +K MQR WIGKS GA+  F+VK+    
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  245  IRVFSTRPDTIFGATFMVLAPEHELVPLITTPEQKaaveayvaaaRMKSEVERQMEDREK  304
            + VF+TRPDT+FGAT+ VLAPEH LV  ITT++Q  AV  Y   A +KS++ R    +EK
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEK  302

Query  305  TGVFTGAYAINPANGKEIPIWIADYVLAGYGTGAIMAVPGQDERDWEFAEKFGLEIIRTV  364
            TGV TG+YAINP NGKE+P+WIADYVLA+YGTGAIMAVP++DERDWEFA +F L+II  +
Sbjct  303  TGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL  362

Query  365  EPPAGWQGKAYTEDGPAINSGFLNGLYVEEAKKKIIEWMEEKGIGEGKVNYRLRDWLISR  424
            E     +  A+TEDG  INS+FL+GL    A  K++EW+E  G+G+ +V YRLRDWL+SR
Sbjct  363  EGGNV-EEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSR  421

Query  425  QRYWGTPIPMIHCDSCGIVPVPYEQLPVVLPTLKDVEDIRPKGK--SPLAAHPEFYECTC  482
            QRYWG PIP+IH +     +VP  +LP+VLP  K   DIRP G   SPLA   +  E T 
Sbjct  422  QRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTK---DIRPSGTGESPLANVTDWLEVTR  478

Query  483  PKCGGPARRdtdtmdtffdSSWYFLRYTDAQNPQAPFDPEKANFWMPVDQYIGGIEHAIL  542
               G  +RR+T+TM    +SSWY+LRY D++N +   D E  + W+PVD Y+GG EHA+L
Sbjct  479  ED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVL  537

Query  543  HLLYSRFFTKFLHDLGLVEAEEPFEGLFTQGMVMGWTNVGEVEVREGRIYFLDDARRSKL  602
            HLLY+RF  K L DLG+V + EPF+ LF QGM++G         R++R  ++   +  K 
Sbjct  538  HLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILG------TSYRDSRGALVATDKVEK-  590

Query  603  ELEQGLTLEEAQKSGAELREEGGKTYFWKPAVMSKSLGNGVMVGPFVKEQGADIARVTIL  662
                        + G+ ++ E G      PA MSKSL N V  +  V + GAD  RV  +
Sbjct  591  ------------RDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEM  638

Query  663  FAAPPENEMIWTEEGVQGAWRYLNRVYRLVAEQRVELKAQPDLLEPATLEGPHKALYQKL  722
            F +P +  + W+EEG++G++++L+RVYRL++ + +               G+   +Y   
Sbjct  639  FMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEI----------TEENSGALDKVY---  685

Query  723  HQTIKKVTEDLEALRFNTAIAALMELLNALGDYRKEHGVTPVYREAVLRYIQMLAPFAPH  782
            ++T+K VTE+++ ++FNTAIA LM ++NA     KE+ + + Y  +   ++Q++APFAPH
Sbjct  686  NETVKAVTEQVDQMKFNTAIAQLMVFVNAAN---KEDKLFSDYAKG---FVQLIAPFAPH  739

Query  783  LAEELWHEFY--DDSVFKAPWPRLDESALVADSFELVVQVNGKLRGKTTVSTQASEEEIK  840
            L+EELW+ +   ++S+   PWP  DES LV +  E+VVQ++GK+++K  V+ + S EE++
Sbjct  740  LGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQ  799

Query  841  RLARTLPNVQQHIAGKEVVKEIYVPGKLLNIVVK  874
             +A +  +VQ +IAGK+++K I VP KL+NIV+K
Sbjct  800  EVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

731) TherJR_2509 in NC_014152


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  601 bits (2272),  Expect = 5e-173, Method: Compositional matrix adjust.
 Identities = 384/857 (45%), Positives = 564/857 (66%), Gaps = 66/857 (7%)

Query  5    YSFKEIETKWQKIWDDMGLHKVKDNRSKPKYYALEMFPYPSG-NLHMGHVRNYSIGDVVA  63
            Y    IE KWQ +W D    K   + SKPK+YAL+MFPYPSG  LH+GH   Y+  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RFKTMQGYNVLHPMGWDAFGLPAENAAIKHGVPPARWTLSNIENMRNQLKRLGFSYDWER  123
            RFK  QG NVLHPMGWDAFGLPAE+ A+  G  PA  T  NI N + Q++ LGFSYDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVTTCLPDYYKWTQWLFLLFYKRGLAYKKKSAVNWCPDCMTVLANEQVV-NGACERCGAQ  182
            EV T  P+YYKWTQW+F  +Y +GLAY    +VNW  +  T +ANE+V+ +G+ ER G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VGKKELAQWFFKITDYADRLLKDIELLKGWPDKVKIMQENWIGRSEGAEVRFKVAETDDE  242
            V +K + QW +KIT YA+RLL D+E + +WP+ +K MQ NWIG+S GA+V FKV +TD +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  ITVYTTRPDTIYGVTFMVLAPEHPLVEKLTRGTAYEAAATEFVQKAQALNEIARTSGDNE  302
            +TV+TTRPDT++G T+ VLAPEH+LV+ +T +     A +++ ++A   +++ART   +E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQ-AEAVADYKRQASLKSDLARTDLAKE  301

Query  303  KEGLFIGVHVINPLTGEKIPLYIANYVLMDYGTGAVMGVPAHDQRDFDFATKYNLPIRPV  362
            K G+  G   INP+ G  +P+ IA+YVL  YGTGA+M+VPAHD+RD +FA ++NL I PV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  363  IVPEGTEPPAVMEEAFEAQGIMINSGPFNGLPNEEALNKIIKYLEEKGIGRGTVNFRLRD  422
            +     E   V E AF  +G+ INS+ ++GL +  A+ K++  LE  G+G   V +RLRD
Sbjct  362  L-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  423  WLISRQRYWGAPIPIIYCDKCGTVPVPEEQLPVMLPDDVEFKP--TGQSPLAECPSFLNT  480
            WL+SRQRYWG PIPII  +   + +VPE +LP++LP   +++P  TG+SPLA+    L+ 
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  481  TCPTCGGPAKRETDTMDTFICSSWYFLRYCSPHAAEVAFERAAVDYWMPVEQYIGGVEHA  540
            T    G  ++RET+TM     SSWY+LRY  PH +E   +   +  W+PV+ Y+GG EHA
Sbjct  477  TRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  541  ILHLLYSRFFAKVLYDAGLVGFEEPFTNLLTQGMVL-------------------KDG--  579
            +LHLLY+RF  KVLYD G+V   EPF +L+ QGM+L                   +DG  
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSF  595

Query  580  -------------AKMSKSKGNVVSPEEIVAKYGADTARLFILFAAPPERDLEWSDQGVE  626
                         AKMSKS  NVV+P+++V +YGADT R++ +F +P +  + WS++G+E
Sbjct  596  FHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLE  655

Query  627  GAFRFLNRVWRLVYNYVSGLDDTAHVEEMSPADREMRRITHVTIKRVTDDISQRFNFNTA  686
            G+ +FL+RV RL+         T ++ E +++   + ++ + T+K VT+++ Q  +FNTA
Sbjct  656  GSRKFLDRVYRLI--------TTKEITEENSG--ALDKVYNETVKAVTEQVDQ-MKFNTA  704

Query  687  ISAIMEMVNALYQYRDKNEKRNSAVEAEAMNSLVLLLAPFAPHIAEELWHEL-GFTDSVH  745
            I+ +M  VNA         +++  + ++  +++V L+APFAPH++EELW+ L +  +S+ 
Sbjct  705  IAQLMVFVNA--------ANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESIS  756

Query  746  TQPWPKYDPAATVQDEVEIVIQVNGKVKERMMAPASLDAGGLQQFAMDQESVQKLIEGkq  805
              PWP YD +  V+++VEIV+Q++GKVK +++ +  L    LQ+ A+ +E VQ  I GK+
Sbjct  757  YVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKD  816

Query  806  vvkvvavpkklvNIVVK  822
            ++KV+AVP+KLVNIV+K
Sbjct  817  IIKVIAVPNKLVNIVIK  833

732) COB47_1302 in NC_014392


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  601 bits (2270),  Expect = 6e-173, Method: Compositional matrix adjust.
 Identities = 379/854 (45%), Positives = 568/854 (67%), Gaps = 63/854 (7%)

Query  3    YNFKEIEKKWQQKWFSQNKYKVSEDSPKPKYYVLEMFPYPSGK-LHMGHVRNYSIGDVFA  61
            Y+   IE KWQ  W  ++ +K + D++KPK+Y L+MFPYPSG  LH+GH   Y+  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  62   RFMRLKGYNVLHPMGWDAFGLPAENAAIKHGIHPSDWTWSNIENMKRQLIELGISYDWDR  121
            RF R +G NVLHPMGWDAFGLPAE+ A+  G +P++ T  NI N KRQ+  LG+SYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  122  EVATCHPDYYKWTQWMFLQFYKAGLAYRKRSYVNWCPSCETVLANEQVV-NGRCERCKSL  180
            EV T +P+YYKWTQW+F ++Y  GLAY     VNW     T +ANE+V+ +G  ER    
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  181  VGKKDLEQWFFRITNYAERLLRDIEKLDGWPEKVKIMQKNWIGRSEGAEIEFEIEGLGKK  240
            V +K + QW ++IT YAERLL D+E +D WPE +K MQ+NWIG+S GA++ F + + +K 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  241  IKVFTTRPDTLFGVTYLVLAPEHPLTKEIIAGKPQEKECLEFIEKMQYLNEIERTSTETE  300
            + VFTTRPDTLFG TY VLAPEH+L  + I+   Q     ++  +    +++ RT    E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALV-DAITTSDQAEAVADYKRQASLKSDLARTDLAKE  301

Query  301  KEGRFTGGYAIHPLTGERVPIYIANYVLVDYGTGAVMGVPAHDQRDFEFAKKYNLPIKVV  360
            K G  TG+YAI+P+ G  +P+ IA+YVL  YGTGA+M+VPAHD+RD EFAK++NL I  V
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  361  IKGEGVDIENLQSAYEDEGVLINSGIFDGLKNTDAMKKITQYLEQKGFGRACVTYKLRDW  420
            + G  V+    ++A+ ++G+ INS+++DGL ++ A+ K+ + LE  G G   VTY+LRDW
Sbjct  362  LEGGNVE----EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDW  417

Query  421  LISRQRYWGAPIPIVYCDECGIvpvpeedlpvllpYNVEFKP--TGQSPLSYCEEFVNTT  478
            L+SRQRYWG PIPI+  ++    +VPE +LP++LP   +++P  TG+SPL+   + ++ T
Sbjct  418  LFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT  477

Query  479  CPKCGRPAKRETDTMDTFICSSWYYFRYTDPKNDQKPFEKSLVSYWLPVDQYIGGVEHAI  538
                 + ++RET+TM     SSWYY+RY DP N +K  +  L+  WLPVD Y+GG EHA+
Sbjct  478  REDGVK-GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  539  LHLLYSRFFTKVLYDLGYVPFEEPFKNLLTQGMVL-------------------KDG---  576
            LHLLY+RF  KVLYDLG VP  EPF++L+ QGM+L                   +DG   
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFF  596

Query  577  ------------AKMSKSLGNIVSPEDIVEKYGADTARLFILFAAPPERDLEWSDQGVEG  624
                        AKMSKSL N+V+P+D+VE+YGADT R++ +F +P +  + WS++G+EG
Sbjct  597  HVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEG  656

Query  625  CFRFLNRLWRLYIELKNKLADDNLVGESELDDELRYRLNYTIKKVTEDIGERFNFNTAIS  684
              +FL+R+ RL       ++  ++  E+    +  Y  N T+K VTE++ ++ +FNTAI+
Sbjct  657  SRKFLDRVYRL-------ITTKEITEENSGALDKVY--NETVKAVTEQV-DQMKFNTAIA  706

Query  685  TIMELLNFLYEYKESEKLNKDLIIDTLRNLLILIYPFTPHIACELWEIM-GFGEDIEEVS  743
               +L+ F+   +  +KL  D      + ++ LI PF+PH++ ELW+ + + GE I  V+
Sbjct  707  ---QLMVFVNAANKEDKLFSDYA----KGFVQLIAPFAPHLGEELWQALTASGESISYVP  759

Query  744  WPQYDEAALVRKNVEIAIQVNGKVRSRMNISVDMTEDEVKQAVLNDQKLKSLLDGKEIVK  803
            WP YDE+ LV ++VEI +Q++GKV++++ ++ D++ +E+++  L ++K+++ + GK+I+K
Sbjct  760  WPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIK  819

Query  804  FVYVKNRLVNIVVK  817
             + V N+LVNIV+K
Sbjct  820  VIAVPNKLVNIVIK  833

733) Calla_0643 in NC_015949


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  600 bits (2268),  Expect = 1e-172, Method: Compositional matrix adjust.
 Identities = 381/854 (45%), Positives = 572/854 (67%), Gaps = 63/854 (7%)

Query  3    YNFREIEKKWQQKWFSQNKYKVSEDSPKPKYYVLEMFPYPSGK-LHMGHVRNYSIGDVFA  61
            Y+   IE KWQ  W  ++ +K + D++KPK+Y L+MFPYPSG  LH+GH   Y+  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  62   RFMRLKGYNVLHPMGWDAFGLPAENAAIKHGIHPSDWTWSNIENMKRQLMELGISYDWDR  121
            RF R +G NVLHPMGWDAFGLPAE+ A+  G +P++ T  NI N KRQ+  LG+SYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  122  EVATCHPDYYKWTQWMFLQFYKAGLAYRKRSYVNWCPSCETVLANEQVV-NGRCERCKSL  180
            EV T +P+YYKWTQW+F ++Y  GLAY     VNW     T +ANE+V+ +G  ER    
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  181  VGKKDLEQWFFRITNYAERLLRDIEKLDGWPEKVKIMQKNWIGRSEGAEIEFEIEGLGKK  240
            V +K + QW ++IT YAERLL D+E +D WPE +K MQ+NWIG+S GA++ F + + +K 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  241  IKVFTTRPDTLFGVTYLVLAPEHPLTKEIIAGKPQERVCLEFIEKMQYLNEIERTSTETE  300
            + VFTTRPDTLFG TY VLAPEH+L   I ++   E V  ++  +    +++ RT    E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVA-DYKRQASLKSDLARTDLAKE  301

Query  301  KEGRFTGGYAIHPLTGEKVPIYIANYVLVDYGTGAVMGVPAHDQRDFEFAKKYNLPIKVV  360
            K G  TG+YAI+P+ G  +P+ IA+YVL  YGTGA+M+VPAHD+RD EFAK++NL I  V
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  361  IKGEGVDIENLQSAYEDEGVLINSGIFDGLKNTDAMKKITQHLEQKGVGRACVTYKLRDW  420
            + G  V+    ++A+ ++G+ INS+++DGL ++ A+ K+ + LE  GVG   VTY+LRDW
Sbjct  362  LEGGNVE----EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDW  417

Query  421  LISRQRYWGAPIPIVYCDECGIvpvpeedlpvllpYNVEFKP--TGQSPLSYCEEFVNTT  478
            L+SRQRYWG PIPI+  ++    +VPE +LP++LP   +++P  TG+SPL+   + ++ T
Sbjct  418  LFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT  477

Query  479  CPKCGKPAKRETDTMDTFICSSWYYFRYTDPKNSQKPFEKSLVSYWLPVDQYIGGVEHAI  538
                 K ++RET+TM     SSWYY+RY DP N++K  +  L+  WLPVD Y+GG EHA+
Sbjct  478  REDGVK-GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  539  LHLLYSRFFTKVLYDLGYVPFEEPFKNLLTQGMVL-------------------KDG---  576
            LHLLY+RF  KVLYDLG VP  EPF++L+ QGM+L                   +DG   
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFF  596

Query  577  ------------AKMSKSLGNIVSPEDIVEKYGADTARLFILFAAPPERDLEWSDQGVEG  624
                        AKMSKSL N+V+P+D+VE+YGADT R++ +F +P +  + WS++G+EG
Sbjct  597  HVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEG  656

Query  625  CFRFLNRLWRLYIELKSKLAdesllgeselddelKYRLNYTIKKVTEDIGERFNFNTAIS  684
              +FL+R+ RL       ++   +  E+    +  Y  N T+K VTE++ ++ +FNTAI+
Sbjct  657  SRKFLDRVYRL-------ITTKEITEENSGALDKVY--NETVKAVTEQV-DQMKFNTAIA  706

Query  685  TIMELLNFLYEYKEKGKLNKDLIIDTLRNLLILIYPFTPHIACELWEIM-GFGEDIEEVS  743
               +L+ F+    + ++ +  L+ D  + ++ LI PF+PH++ ELW+ + + GE I  V+
Sbjct  707  ---QLMVFV----NAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVP  759

Query  744  WPQYDEAALVRKNVEIAIQVNGKVRSRMSISVDMTEDEVKQAVLNDQKLKSLLDGKEIVK  803
            WP YDE+ LV ++VEI +Q++GKV++++ ++ D++ +E+++  L ++K+++ + GK+I+K
Sbjct  760  WPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIK  819

Query  804  FVYVKNRLVNIVVK  817
             + V N+LVNIV+K
Sbjct  820  VIAVPNKLVNIVIK  833

734) leuS in NC_011884


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  600 bits (2265),  Expect = 2e-172, Method: Compositional matrix adjust.
 Identities = 390/857 (46%), Positives = 569/857 (67%), Gaps = 34/857 (3%)

Query  5    YQPTAIEEKWQQTWAEVGIDQTPTDRSKPKFYALSMFPYPSG-NLHMGHVRNYTITDVIA  63
            Y+ TAIE KWQ  WA+    +T TD SKPKFYAL MFPYPSG  LH+GH   YT TD+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RVRRMQGYRVLHPMGWDAFGLPAENAAIKRGIHPAKWTADNITQMRSELKRLGLSYDWNC  123
            R +R QG  VLHPMGWDAFGLPAE+ A+  G +PA  TA+NI++ + +++ LG+SYDW+ 
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCSPDYYRWTQWIFLQFYQAGLAYQKEAAVNWDPIDQTVLANEQVDSEGRSWRSGAK  183
            E+ T  P+YY+WTQWIF ++Y+ GLAY+ E +VNW     T +ANE+V ++G S R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  184  VERKLLRQWFLKITDYAEELLQDLDQLTGWPEKVRKLQANWIGKSTGAYLEFPIVGRDEK  243
            V RK +RQW LKIT YAE LL+DL+++ +WPE ++ +Q NWIGKSTGA + F + + D  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  244  ISVYTTRPDTVYGVSYVVLAPEHPLTLQVTTKKQLKAVKSFIQEVTAASEIERTAEDQPK  303
            ++V+TTRPDT++G +Y VLAPEH+L   +TT  Q  AV  + ++ +  S++ RT   + K
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEK  302

Query  304  RGIATGGKAINPFTGAEIPIWIADYVLYEYGTGAVMGVPAHDSRDFKFAQTYQLPIRQVI  363
             G+ TG+ AINP  G E+P+WIADYVL  YGTGA+M+VPAHD RD  FA+ ++L I  V 
Sbjct  303  TGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV-  361

Query  364  IPPDPDLNEQPILQEAYTEPGLLINSGEFDGMPSTDakaaivakaeaTGWGQARVQYRLR  423
                  L+   + + A+TE GL INS+ +DG+  + A A +V   EA G G+  V YRLR
Sbjct  362  ------LEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  424  DWLISRQRYWGAPIPVIHCPQCGIVPVPEADLPVVLP--DDVQFSGRGPSPLAQLESWVK  481
            DWL+SRQRYWG PIP+IH  +    +VPE++LP+VLP   D++ SG G SPLA++  W+ 
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  482  VNCPTCNTPARRETDTMDTFIDSSWYYLRYPDAQNDQQVFDPAKTNDWLPVDQYVGGIEH  541
            V        +RRET+TM    +SSWYYLRY D++N +++ D    ++WLPVD YVGG EH
Sbjct  476  VTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEH  534

Query  542  AILHLLYSRFFTKVLRDRGLLNFDEPFQRLLTQGMVQGLTYTNPNRSDSSRYIPSNLVDP  601
            A+LHLLY+RF  KVL D G++   EPFQ+L+ QGM+ G +Y    R   +  ++++ V+ 
Sbjct  535  AVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY----RDSRGALVATDKVEK  590

Query  602  NDPK--DPETGEPLEVSYQTMSKSKYNGVAPEEVINKYGADTARMFILFKAPPEKDLEWD  659
             D    + ETGE LE +   MSKS  N V P++V+++YGADT R++ +F +P +  + W 
Sbjct  591  RDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWS  650

Query  660  DADVEGQFRFLNRVWRLVTQYPVIEPTTKQGDALAKEEKELRRAIHTAIKEITADLGEEY  719
            + ++EG  +FL+RV RL+T   + E  +            L +  + ++K +T ++ ++ 
Sbjct  651  EEGLEGSRKFLDRVYRLITTKEITEENS----------GALDKVYNETVKAVTEQV-DQM  699

Query  720  QLNTAVSELMKLSNALTDASCKDSVIYTEGIETLLLLLAPFAPHISEELWQQLGHTT-SV  778
            ++NTA+++LM     + +A+ K+  ++++    ++ L+APFAPH++EELWQ L  +  S+
Sbjct  700  KFNTAIAQLM----VFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESI  755

Query  779  HQQSWPQVDPSALIVDEITIVIQILGKTRGTIQVPASSSREELEEYARQTPVAQRYLEGK  838
               +WP  D S L+ +++ IV+QI GK ++ + V+   SREEL+E A      Q  + GK
Sbjct  756  SYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGK  815

Query  839  TIKKVIVVPGKLVNFVV  855
             I KVI VP KLVN+V+
Sbjct  816  DIIKVIAVPNKLVNIVI  832

735) leuS in NC_008346


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  599 bits (2264),  Expect = 2e-172, Method: Compositional matrix adjust.
 Identities = 379/859 (45%), Positives = 561/859 (66%), Gaps = 68/859 (7%)

Query  5    YDFKSIEAKWQAYWENKQLFKVEEDPEKPKYYNLEMFPYPSGH-LHMGHVRNYAIGDVVA  63
            YD  +IE+KWQA+W +++ FK   D+ KPK+Y L+MFPYPSG  LH+GH   Y+  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RFKSMNGFNVLHPMGWDAFGLPAENAAIKNAIHPATWTYSNIENMKRQLKTMGISYDWDR  123
            RFK  +G NVLHPMGWDAFGLPAE+ A+  + +PA  T  NI N KRQ++++G+SYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCKPDYYKFTQWMFLKLYENKLAYKKKSAVNWCPSCQTVLANEQVV-DGACERCEAV  182
            E+ T  P+YYK TQW+F KLYE+ LAY    +VNW     T +ANE+V+ DG+ ER    
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  IEKKQLEQWFFKITDYAQRLLDDLALLPGWPEKVKTMQKNWIGRSEGCEFSLHIEDSDEV  242
            + +K + QW +KIT YA+RLL+DL  + +WPE +K MQ+NWIG+S G + ++ + D+D  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVFTTRPDTVFGVTYMVLAPEHPLVEKICHPEQEKEVKAFVNKMKYLNEMARTSTEAEK  302
            +TVFTTRPDT+FG TY VLAPEH+LV+ I  ++Q   V  +  +    +++ART    EK
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEK  302

Query  303  EGVFTGAYAINPMDGSRIPIWIANYVLMDYGTGAIMAVPAHDQRDFEFARKYDIPVKVVI  362
             GV TG+YAINP++G  +P+WIA+YVL  YGTGAIMAVPAHD+RD EFA+++++ +  V+
Sbjct  303  TGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL  362

Query  363  KGEDTPLDGNLLQESYPGDGHMVNSGNFDGLTVEEGQKAVIKFMEEKGIGQGTVNYRLRD  422
             G      GN+ + ++  DG  +NS+ +DGL    +   ++  +E  G+G+  V YRLRD
Sbjct  363  EG------GNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  423  WLISRQRYWGAPIPIVYCPECGPVAVpeeelplylpeDIDFKP--YAESPLKHLERFYKT  480
            WL+SRQRYWG PIPI+   +  + AVPE ELPL LP   D++P   +ESPL ++      
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  481  TCPSCGKEALRETDTMDTFVCSSWYFDRFCSPHESKQPFSREAVDYWMPVDQYIGGVEHA  540
            T     K   RET+TM     SSWY+ R+  PH++ +    E +  W+PVD Y+GG EHA
Sbjct  477  TREDGVKGR-RETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  541  ILHLMYARFFTKFLFDINVLSCQEPFTRLLTQGMVL------------------------  576
            +LHL+YARF  K L+D+ V++ +EPF +L+ QGM+L                        
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSF  595

Query  577  ----------KDNAKMSKSKGNVVSPEEIIDTYGADTARLFILFASPPERDLEWSEQGVE  626
                      +  AKMSKS  NVV+P+++++ YGADT R++ +F +P +  + WSE+G+E
Sbjct  596  FHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLE  655

Query  627  GAFRFLNRVWRLVSELAEGIKDLPAAEHFPELDSEAKNLRFKTHATIKKVTEDIGERFNF  686
            G+ +FL+RV RL++           + ++ E +S A +  +  + T+K VTE++ ++ +F
Sbjct  656  GSRKFLDRVYRLIT-----------TKEITEENSGALDKVY--NETVKAVTEQV-DQMKF  701

Query  687  NTAISAIMELSNTLGAYKGIKKPNWPVVKEAVDNLLILLSPFSPHICEELWQ-LTGHAES  745
            NTAI+ +M + N+  A K  K     +  +    ++ L++PF+PH+ EELWQ LT+ +ES
Sbjct  702  NTAIAQLMVFVNA--ANKEDK-----LFSDYAKGFVQLIAPFAPHLGEELWQALTASGES  754

Query  746  IYLQKWPKYDPEALLQEEIEIVLQISGKVRDRIMVPVDAGREELEKIALDNPKIRELTRG  805
            I    WP YD   L+++++EIV+QI GKV+ +++V+ D +REEL+ +AL N K++    G
Sbjct  755  ISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAG  814

Query  806  KEIVKLIVVPGKLVNVVAK  824
            K+I+K+I VP KLVN+V K
Sbjct  815  KDIIKVIAVPNKLVNIVIK  833

736) Marpi_0359 in NC_016751


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  599 bits (2263),  Expect = 3e-172, Method: Compositional matrix adjust.
 Identities = 378/837 (46%), Positives = 543/837 (65%), Gaps = 70/837 (8%)

Query  3    FDHIQIEKKWQKKWSDKNVFKTEQRNEKEKYYVLTMFPYPSGT-IHVGHVKNYVIGDVVA  61
            +DH  IE KWQ  W+D++ FKT     K K+Y L MFPYPSG+ +HVGH   Y   D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  62   RYKKMQGYNVLHPFGYDAFGLPAENAAIKRNVNPGEWTFKNIETIREQIKKIGISYDWDR  121
            R+K+ QG NVLHP G DAFGLPAE+ A+    +P+E T  NI  ++ QI+ +G+SYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  122  EIATCTEDYYKWTQWIFLKLYEKGLAYKKHAAVNWCPSCKTVLANEQVV-NGKCERCGTD  180
            E+ T   +YYKWTQWIF KLYEKGLAY  + +VNW     T +ANE+V+ +G  ER G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  181  IEMKKLEQWYFKITDYSERLLNDLEKLEGWPENVKVMQKNWIGKSVGAEVNFKIDGTDKE  240
            +  K + QW +KIT Y+ERLL+DLE ++ WPE++K MQ+NWIGKS GA+V FK+ +TDK+
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  241  LKVFTTRPDTLWGVTFMALAPESPLVEELTTPEQKEEVESFLNRVNKEDKFKRIAQGAKK  300
            + VFTTRPDTL G T+  LAPE +LV+ +TT++Q E V  +  + +    + R   +  K
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEK  302

Query  301  DGAFTGSYAVNPVNGEKIPIYVANYILFEYGTGAIMAVPAHDQRDFEFAKEFNLPIRVVI  360
             G  TGSYA+NPVNG  +P+ +A+Y+L  YGTGAIMAVPAHD+RD EFAK+FNL I  V+
Sbjct  303  TGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL  362

Query  361  TPkdkelkaedleeaFTEDGIMINSDKFNGMKNREALTKIVEWLEENGYGKKSIQYKLRD  420
                    ++  E AFTEDG+ INSD ++G+ +  A++K+VEWLE +G G+ ++ Y+LRD
Sbjct  363  EG------GNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  421  WLISRQRYWGAPIPVVYCEKCGTVPVPEKDLPVKLPT--DVKFEPTGKSPLATNEDFINT  478
            WL+SRQRYWG PIP++  E   + +VPE +LP+ LP   D++   TG SPLA   D ++ 
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  479  TCPKCGGPARREVDTMDTFVDSSWYYLRYINPKMEDKPFDSDDVNYWLPVDQYIGGVEHA  538
            T    G  +RRE +TM    +SSWYYLRYI+P   +K  D + ++ WLPVD Y+GG EHA
Sbjct  477  TRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  539  ILHLLYSRFITKVLHDLGYVNFEEPFSNLFTQGMI----YKDG-----------------  577
            +LHLLY+RF  KVL DLG V   EPF +LF QGMI    Y+D+                 
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSF  595

Query  578  -------------AKMSKSKGNVVSPDEMIEKYGADTLRLYMLFMGPPEKDAEWNDAGLE  624
                         AKMSKS  NVV+PD+++E+YGADTLR+Y +FMGP +    W++ GLE
Sbjct  596  FHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLE  655

Query  625  GVARFMNKVWNSMTKIIEFSKDGNINNINLTTKEEKNLRRKLHQMIKKITNDIEKNFQFN  684
            G  +F+++V         +     I   ++T  +   L +  ++ +K +T++++ + +FN
Sbjct  656  GSRKFLDRV---------YRL---ITTKEITEENSGALDKVYNETVKAVTEQVD-QMKFN  702

Query  685  TAISGMMELINELNAYLNSVPQEKWNKDLLKELSEDFVILISPFAPHLAEELWE-MMGHE  743
            TAI+ +M ++N  N           +  L+ + + +FV LI+PFAPHL+EELW+ + +  
Sbjct  703  TAIAQLMVFVNAANK----------EDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASG  752

Query  744  DFVLNAQWPTVDEEALKVDEIEIVIQINGKVRDKMIVDASASEDEIKEKAFELDKIK  800
            + +    WP+ DE  L  +++EIV+QI+GKV+ K++V    S +E++E A+  +K++
Sbjct  753  ESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQ  809

737) Cal7507_5836 in NC_019682


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  599 bits (2263),  Expect = 3e-172, Method: Compositional matrix adjust.
 Identities = 386/873 (45%), Positives = 580/873 (67%), Gaps = 47/873 (5%)

Query  1    MDFRYNPATIEEKWQKTWAELGLDQTPTDNDKPKFYALSMFPYPSGS-LHMGHVRNYTIT  59
            M F Y+ ++IE KWQ  WA+    +T TD  KPKFYAL MFPYPSG+ LH+GH   YT T
Sbjct  1    MTF-YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTAT  59

Query  60   DVIARLKRMQGYRVLHPMGWDAFGLPAENAAIDRGVPPAKWTYQNIAQMRQQLQRLGLSI  119
            D+++R+KR QG  VLHPMGWDAFGLPAE+ A+D G  PA  T +NIA+ ++Q++ LG+S 
Sbjct  60   DILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSY  119

Query  120  DWDCEVATCSPDYYKWTQWIFLQFLQAGLAYQKEAAVNWDPIDQTVLANEQVDNEGRSWR  179
            DWD EV T  P+YYKWTQWIF ++ + GLAY+ E +VNW     T +ANE+V  +G S R
Sbjct  120  DWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSER  179

Query  180  SGAIVERKLLRQWFLKITDYAEELLNDLDKLTGWPERVKLMQANWIGKSTGAYLEFPIVG  239
            +G  V RK +RQW LKIT YAE LL+DL+ + +WPE +K MQ NWIGKSTGA + F + +
Sbjct  180  GGYPVVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKD  238

Query  240  IDEKVSVYTTRPDTVYGVSYLVLAPEHPLTKRVTTKEQQGIVDVFSKEVANQTELERTAE  299
             D   +V+TTRPDT++G +Y VLAPEH+L   +TT +Q   V  + ++ + +++L RT  
Sbjct  239  TDKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDL  298

Query  300  DKPKRGVPTGGKAINPFNGEEVPIWIADYVLYEYGTGAVMGVPAHDVRDFKFANKYNLPI  359
             K K GV TG+ AINP NG E+P+WIADYVL  YGTGA+M+VPAHD RD  FA+++NL I
Sbjct  299  AKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDI  358

Query  360  EFVIVPPEAVADEDFRQEDPPLIMISYDSAYTEPGILINSGQFSGVASGEAKQTIVAYAE  419
             + ++    V                 ++A+TE G+ INS+ + G+  + A   +V   E
Sbjct  359  -IPVLEGGNVE----------------EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLE  401

Query  420  QQGFGKARVQYRLRDWLISRQRYWGAPIPVIHCPNCGIVPVPDQDLPVQLP--EEVEFTG  477
             +G G+  V YRLRDWL+SRQRYWG PIP+IH  +    +VP+ +LP+ LP   ++  +G
Sbjct  402  AEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSG  461

Query  478  RGGSPLTQLENWVNVPCPNCGTPAQRETDTMDTFIDSSWYFLRFPDAKNGQQIFDAAKTN  537
             G SPL+++ +W++V   + G  ++RET+TM    +SSWY+LR+ D+ N +++ D    +
Sbjct  462  TGESPLANVTDWLEVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLK  520

Query  538  DWMPVDQYVGGIEHAILHLLYSRFFTKVLRDRGLLNFDEPFQRLLTQGMVQGLTYLNPNK  597
            +W+PVD YVGG EHA+LHLLY+RF  KVL D G++   EPFQ+L+ QGM+ G +Y    +
Sbjct  521  QWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY----R  576

Query  598  GGKDKWIPSHLVNSGEPR--DPQTGEPLQRLYATMSKSKGNGVAPEDVIGKYGVDTARMF  655
            ++++  ++++ V+  +    + +TGE L++  A MSKS  N V P+DV+ +YG DT R++
Sbjct  577  DSRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVY  636

Query  656  ILFKAPPEKDLEWDEADVEGQFRFLNRVWRLVTDYVAAGVSRKQAQLADLTKPEKELRRA  715
             +F +P +  + W E ++EG  +FL+RV RL+T   +  ++  ++           L + 
Sbjct  637  EMFMGPLDASIAWSEEGLEGSRKFLDRVYRLIT---TKEITEENSG---------ALDKV  684

Query  716  IHIAIQAVTEDVQDEYQFNTAISELMKLSNALTDTSSKNSPIYAEGIRTLVVLLAPFAPH  775
             + +++AVTE+V D+ +FNTAI++LM     + ++++K+  ++++  + +V L+APFAPH
Sbjct  685  YNETVKAVTEQV-DQMKFNTAIAQLM----VFVNAANKEDKLFSDYAKGFVQLIAPFAPH  739

Query  776  ISDELWHLLGNTS-SIHTQTWPSFDPTALVADEITLVIQIMGKTRGAIQVPSQADKAELE  834
            +++ELW+ L  ++ SI    WPS+D + LV +++ +V+QI GK ++ + V+ +  + EL+
Sbjct  740  LGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQ  799

Query  835  KYARESEIAQRYIEGKEIKKVIVVPGKLVNFVI  867
              A  +E  Q  I GK+I KVI VP KLVN+VI
Sbjct  800  EVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

738) Ocepr_0474 in NC_014761


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  599 bits (2263),  Expect = 3e-172, Method: Compositional matrix adjust.
 Identities = 394/883 (45%), Positives = 574/883 (66%), Gaps = 58/883 (6%)

Query  1    MSKYNPHAIEPKWQRFWEERGLMKAREEGAK--YYVLEMFPYPSG-DLHMGHLKNYTMGD  57
            M+ Y+  AIEPKWQ FW +    K+  +++K  +Y L+MFPYPSG +LH+GH   YT  D
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  58   ALARFKKQQGYSVLHPMGWDAFGLPAENAALKFGKHPADWTFDNIAKAKESLNLMGILYD  117
             L+RFK+ QG +VLHPMGWDAFGLPAE+ A+  G++PA+ T +NIA+ K  +N +G+ YD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  118  WDREVTTCTPDYYRWNQWIFIKMYEAGLVYRAGGLVNWCPKCQTVLANEQVVEGRCWRHE  177
            WDREV T  P+YY+W QWIF K+YE GL Y A   VNW     T +ANE+V+ +    + 
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  178  DTLVEKKNLEQWYLKITAYADRLLDDLDKLEHWPEKVKAMQRAWIGRSEGATVKFALEGR  237
            +  V +K + QW LKITAYA+RLL+DL+ ++ WPE +K MQR WIG+S GA V F + + 
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDT  239

Query  238  DEALEVFTTRPDTLFGATFMVIAPEHPLTLELATPerraeveeyvraSQLKSEIERQTED  297
            D  + VFTTRPDTLFGAT+ V+APEH+L   ++T+++   V +Y R + LKS++ R    
Sbjct  240  DKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA  299

Query  298  REKTGVFTGAYAINPVNGRKVPIWTADYVLYGYGTGAIMAVPAHDQRDFEFARKFGLEIV  357
            +EKTGV TG+YAINPVNG+ +P+W ADYVL +YGTGAIMAVPAHD+RD EFA++F L+I+
Sbjct  300  KEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDII  359

Query  358  PVVKPEGEDLPEPLEAAYEGPGVMINSGEFTGLPSEEGKKKITEWLAAKGLGEATVTYRL  417
            PV+     +     EAA+   G+ INS+ + GL    +  K+ EWL A G+G+  VTYRL
Sbjct  360  PVLEGGNVE-----EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRL  414

Query  418  RDWLISRQRYWGTPIPMIHCENCGVVPVPEDQLPVELPEIKDVEQIRPQGKSPLEAHPEF  477
            RDWL+SRQRYWG PIP+IH E+    +VPE +LP+ LP  KD+ +    G SPL    + 
Sbjct  415  RDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDI-RPSGTGESPLANVTDW  473

Query  478  IRTTCPKCGGPARRDADTMDTFFDSSWYYLRYTDAHNERRPFARDKADYWMPVDQYIGGI  537
            +  T    G  +RR+++TM    +SSWYYLRY D+HN  +    +    W+PVD Y+GG 
Sbjct  474  LEVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGA  532

Query  538  EHAVLHLLYSRFFTKFFHDQKMVAVDEPFERLFTQGMVMGWTDYGPVQ---VEGERVRLS  594
            EHAVLHLLY+RF  K + D  +V+  EPF++LF QGM++G T Y   +   V  ++V   
Sbjct  533  EHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILG-TSYRDSRGALVATDKVEKR  591

Query  595  EEARIRLELETSELSRDDVKKMGAELREGEDGHLHFWKPAVMSKSLGNGVMVGPFVREQG  654
            + + +++E              G EL ++         PA MSKSL N V  +  V + G
Sbjct  592  DGSFFHVE-------------TGEELEQA---------PAKMSKSLKNVVNPDDVVEQYG  629

Query  655  ADIARVTILFAAPPEKEMVWTEEGVQGAWRFLNRVWRRVVEDEEALRQAPEAFDPARLEG  714
            AD  RV  +F +P +  + W+EEG++G+++FL+RV R +   E +             E 
Sbjct  630  ADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEIT-------------EE  676

Query  715  ADKTLYRKLNQTIKKVTEDVEGLRFNTAIAALMEMLNALYDFRKTSEANAVYKNAVLGYL  774
               +L +  N+T+K VTE+V+ ++FNTAIA LM  +NA      ++  + ++ +   G++
Sbjct  677  NSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNA------ANKEDKLFSDYAKGFV  730

Query  775  QLLAPFAPHIAEELWHRF--NENSVFDARWPTYDEaalaadtltlVVQVNGKVRARIEVP  832
            QL+APFAPH++EELW+ +  + +S+    WP+YDE+ L  + + +VVQ++GKV+A++ V+
Sbjct  731  QLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVA  790

Query  833  AEIDKDEAIARAKAHENVRRHLEGKQLVKEIYVPGKLVNLVAK  875
             ++ ++E    A A+E+V+ ++ GK+++K I VP KLVN+V K
Sbjct  791  KDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

739) leuS in NC_007413


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  599 bits (2263),  Expect = 3e-172, Method: Compositional matrix adjust.
 Identities = 378/873 (44%), Positives = 579/873 (67%), Gaps = 50/873 (5%)

Query  5    YNPAILEEKWQKTWVELGLDKTQTQSNKPKFYALSMFPYPSGS-LHMGHVRNYTITDVIA  63
            Y+ + +E KWQ  W +    KT T+++KPKFYAL MFPYPSG+ LH+GH   YT TD+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RLKRMQGYRVLHPMGWDAFGLPAENAAIDRGVPPANWTYQNITQMRQQLQRLGLSIDWDS  123
            R+KR QG  VLHPMGWDAFGLPAE+ A+D G  PA+ T +NI++ ++Q++ LG+S DWD 
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVATCSPDYYKWTQWIFLQFLQAGLAYQKEAAVNWDPIDQTVLANEQVDNEGRSWRSGAI  183
            EV T  P+YYKWTQWIF ++ + GLAY+ E +VNW     T +ANE+V  +G S R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  184  VERKLLRQWFLKITDYAEELLNDLDKLTGWPERVKLMQANWIGKSVGAYLEFPIVGSTEK  243
            V RK +RQW LKIT YAE LL+DL+ + +WPE +K MQ NWIGKS GA + F + ++   
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  244  IAVYTTRPDTVYGVSYVVLAPEHPLTKQVTSKTQQAVVDTFIQEVTNQSELERTAEDKPK  303
            ++V+TTRPDT++G +Y VLAPEH+L   +T+  Q   V  + ++ + +S+L RT   K K
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEK  302

Query  304  RGVATGGKAINPFTGEEVPIWIADYVLYEYGTGAVMGVPAHDVRDFKFAQRYDLPIDFVI  363
             GV TG+ AINP  G E+P+WIADYVL  YGTGA+M+VPAHD RD  FA++++L I  V+
Sbjct  303  TGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL  362

Query  364  AAPDDVAGFDLSPTSeteevtqvvqIEYNQAYTEPGILINSGAFTGMTSTDAKQAIVKYA  423
             + +                     +E + A+TE G+ INS+ + G+  + A   +V   
Sbjct  363  EGGN---------------------VE-EAAFTEDGLHINSDFLDGLDKASAIAKMVEWL  400

Query  424  TEKGFGKERIQYRLRDWLISRQRYWGAPIPVIHCPNCGIVPVPDKDLPVILP--EEVEFT  481
               G G+E + YRLRDWL+SRQRYWG PIP+IH  +    +VP+ +LP++LP   ++  +
Sbjct  401  EAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPS  460

Query  482  GRGGSPLAQLESWVNVPCPTCGSPAKRETDTMDTFIDSSWYFLRFTDARNEAQVFESAKT  541
            G G SPLA++  W++V     G  ++RET+TM    +SSWY+LR+ D++N  ++ +    
Sbjct  461  GTGESPLANVTDWLEVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELL  519

Query  542  NDWMPVDQYVGGIEHAILHLLYSRFFTKVLRDRGLLNFDEPFERLLTQGMVQGLTYFNPN  601
            ++W+PVD YVGG EHA+LHLLY+RF  KVL D G++   EPF++L+ QGM+ G +Y    
Sbjct  520  KQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY----  575

Query  602  KGGKDKWVPSHLVNPNDPR--DPQTGEPLQRLYATMSKSKGNGVAPEDVIAKYGVDTARM  659
            +++++  V+++ V+  D    + +TGE L++  A MSKS  N V P+DV+ +YG DT R+
Sbjct  576  RDSRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRV  635

Query  660  FILFKAPPEKDLEWDEADVEGQFRFLNRVWRLVTDYVASGVNPKNKSGELSKSEKDLRRA  719
            + +F +P +  + W E ++EG  +FL+RV RL+T   +  +   N ++        L + 
Sbjct  636  YEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLIT---TKEITEENSGA--------LDKV  684

Query  720  IHSAIQSVTEDLEDEYQFNTAISELMKLSNALTDANGKDSRVYAEGIHTLVVLLAPFAPH  779
             + ++++VTE++ D+ +FNTAI++LM     + +A  K+ +++++    +V L+APFAPH
Sbjct  685  YNETVKAVTEQV-DQMKFNTAIAQLM----VFVNAANKEDKLFSDYAKGFVQLIAPFAPH  739

Query  780  IAEELWQ-LLGNSESVHTQTWPAFDPAALVADEITLVIQVNGKKRADIQVPSQADKAELE  838
            ++EELWQ L +++ES+    WP++D + LV +++ +V+Q++GK +A + V+ +  + EL+
Sbjct  740  LGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQ  799

Query  839  KYARESEVVQRHLEGKEIKKVIVVPGKLVNFVV  871
              A  +E VQ ++ GK+I KVI VP KLVN+V+
Sbjct  800  EVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

740) Calkr_1236 in NC_014721


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  599 bits (2261),  Expect = 4e-172, Method: Compositional matrix adjust.
 Identities = 381/854 (45%), Positives = 569/854 (67%), Gaps = 63/854 (7%)

Query  3    YNFREIEKKWQQKWFSQNKYKVSEDSPKPKYYVLEMFPYPSGK-LHMGHVRNYSIGDVFA  61
            Y+   IE KWQ  W  ++ +K + D++KPK+Y L+MFPYPSG  LH+GH   Y+  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  62   RFMRLKGYNVLHPMGWDAFGLPAENAAIKHGIHPSDWTWSNIENMKRQLMELGISYDWDR  121
            RF R +G NVLHPMGWDAFGLPAE+ A+  G +P++ T  NI N KRQ+  LG+SYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  122  EVATCHPDYYKWTQWMFLQFYKAGLAYRKRSYVNWCPSCETVLANEQVV-NGRCERCKSL  180
            EV T +P+YYKWTQW+F ++Y  GLAY     VNW     T +ANE+V+ +G  ER    
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  181  VGKKDLEQWFFRITNYAERLLRDIEKLDGWPEKVKIMQKNWIGRSEGAEIEFEIEGLGKK  240
            V +K + QW ++IT YAERLL D+E +D WPE +K MQ+NWIG+S GA++ F + + +K 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  241  IKVFTTRPDTLFGVTYLVLAPEHPLTKEIIAGKPQERECLEFIEKMQYLNEIERTSTETE  300
            + VFTTRPDTLFG TY VLAPEH+L   I ++   E    ++  +    +++ RT    E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAE-AVADYKRQASLKSDLARTDLAKE  301

Query  301  KEGRFTGGYAIHPLTGEKVPIYIANYVLVDYGTGAVMGVPAHDQRDFEFAKKYNLPIKVV  360
            K G  TG+YAI+P+ G  +P+ IA+YVL  YGTGA+M+VPAHD+RD EFAK++NL I  V
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  361  IKGEGVDIENLQSAYEDEGVLINSGIFDGLKNTDAMKKITQHLEQKGVGRACVTYKLRDW  420
            + G  V+    ++A+ ++G+ INS+++DGL ++ A+ K+ + LE  GVG   VTY+LRDW
Sbjct  362  LEGGNVE----EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDW  417

Query  421  LISRQRYWGAPIPIVYCDECGIvpvpeedlpvllpYNVEFKP--TGQSPLSYCEEFVNTT  478
            L+SRQRYWG PIPI+  ++    +VPE +LP++LP   +++P  TG+SPL+   + ++ T
Sbjct  418  LFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT  477

Query  479  CPKCGKPAKRETDTMDTFICSSWYYFRYTDPKNSQKPFEKSLVSYWLPVDQYIGGVEHAI  538
                 K ++RET+TM     SSWYY+RY DP N++K  +  L+  WLPVD Y+GG EHA+
Sbjct  478  REDGVK-GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  539  LHLLYSRFFTKVLYDLGYVPFEEPFKNLLTQGMVL-------------------KDG---  576
            LHLLY+RF  KVLYDLG VP  EPF++L+ QGM+L                   +DG   
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFF  596

Query  577  ------------AKMSKSLGNIVSPEDIVEKYGADTARLFILFAAPPERDLEWSDQGVEG  624
                        AKMSKSL N+V+P+D+VE+YGADT R++ +F +P +  + WS++G+EG
Sbjct  597  HVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEG  656

Query  625  CFRFLNRLWRLYIELKSKLAdesllgeselddelKYRLNYTIKKVTEDIGERFNFNTAIS  684
              +FL+R+ RL       ++   +  E+    +  Y  N T+K VTE++ ++ +FNTAI+
Sbjct  657  SRKFLDRVYRL-------ITTKEITEENSGALDKVY--NETVKAVTEQV-DQMKFNTAIA  706

Query  685  TIMELLNFLYEYKEKGKLNKDLIIDTLRNLLILIYPFTPHIACELWEIM-GFGEDIEEVS  743
               +L+ F+   +  +KL  D      + ++ LI PF+PH++ ELW+ + + GE I  V+
Sbjct  707  ---QLMVFVNAANKEDKLFSDYA----KGFVQLIAPFAPHLGEELWQALTASGESISYVP  759

Query  744  WPQYDEAALVRKNVEIAIQVNGKVRSRMSISVDMTEDEVKQAVLNDQKLKSLLDGKEIVK  803
            WP YDE+ LV ++VEI +Q++GKV++++ ++ D++ +E+++  L ++K+++ + GK+I+K
Sbjct  760  WPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIK  819

Query  804  FVYVKNRLVNIVVK  817
             + V N+LVNIV+K
Sbjct  820  VIAVPNKLVNIVIK  833

741) leuS in NC_004557


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  599 bits (2261),  Expect = 4e-172, Method: Compositional matrix adjust.
 Identities = 379/846 (45%), Positives = 562/846 (67%), Gaps = 58/846 (6%)

Query  22   TNIDRKWQNKWEDSNLYHFDTNNLDKKLYVLEMFSYPSGSNLHAGHWFNYGPSDSWARFK  81
            T I+ KWQ  W D++ +  +T+    K+Y L+MF+YPSG+ LH GH   Y ++D  +RFK
Sbjct  7    TAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSRFK  66

Query  82   RMQGFNVFQPMGFDSFGLPAENYAIKTGVHPKDSTMKNIETMTKQLKSMGAMFHWDNEVI  141
            R QG NV++PMG D+FGLPAE+YA+ TG +P + T  NI    +Q++++G  ++WD EV 
Sbjct  67   RAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDREVN  126

Query  142  TSEPEYYKWTQWMFLQLYKNNLAYRKNAPVNWCPSCNTVLANEQVL-DGACERCSSDVIK  200
            T++P+YYKWTQW+F +LY + LAY  + PVNW     T +ANE+VL DG+ ER +  V++
Sbjct  127  TTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVR  186

Query  201  KDLTQWFFKITDYAeelleklddldWPENTKSMQKHWIGKSIGAQLTFKIVDSDLSFDIF  260
            K + QW +KIT YAE LLE L+++DWPE+ K MQ++WIGKS GA++TFK+ D+D  F +F
Sbjct  187  KPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVF  246

Query  261  TTRADTLFGVTYAVLAPENPLVDKITKEDHKAEIEAYKEQAKKQSEIERQSITREKTGVF  320
            TTR+DTLFG TYAVLAPE++LVD IT  D+   +  YK QA  +S++ R  +++EKTGV 
Sbjct  247  TTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVW  306

Query  321  TGSYAINPINGKKVPVWVGDYVLSTYGTGAVMAVPAHDERDFEFAKKHNLPIEKVIEGG-  379
            TGSYAINP+NGK +PVW++DYVL++YGTGA+MAVPAHDERD EFAK+ NL I  V+EGG 
Sbjct  307  TGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGN  366

Query  380  -ETLPYTEDGIMINSEEFNGLESSKGRSAVVEKLEKENLGVKKINYRLRDWLVSRQRYWG  438
             E  ++TEDG+ INS+ ++GL+ + + + +VE LE E +G  ++ YRLRDWL SRQRYWG
Sbjct  367  VEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWG  426

Query  439  APIPIVYCDKCGTVAVPEEQLPVKLPYDVEFTPDGK--SPLSKCDSFVNTTCPTCGGPAK  496
             PIPI+  +   + AVPE +LP+ LP   ++ P G   SPL++    ++ T    G  ++
Sbjct  427  EPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED-GVKGR  485

Query  497  REVDTLDTFVCSSWYFLRYADNKNSEKAFDPKIINEILPVDKYVGGPEHACMHLLYARFF  556
            RE +T+     SSWY+LRY D  N+EK  D  ++++ LPVD YVGG+EHA +HLLYARF 
Sbjct  486  RETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFW  545

Query  557  TKALRDMGYLNFDEPFSSLTHQGLILGP----------------------------DGL-  587
             K L D+G +   EPF  L +QG+ILG                             + L 
Sbjct  546  HKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEELE  605

Query  588  ----KMSKSKGNTISPDDYIDEFGSDVFRMYLMFGFDYTEGGAWSDEGIKSVSRFVDRVE  643
                KMSKS  N ++PDD ++++G+D +R+Y MF      + AWS+EG+ +  +F+DRV 
Sbjct  606  QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVY  665

Query  644  RTLASCRYYINNPSDDKITIDNNEKDLNFVRHNSIKSITEDAEKMQFNTCIARLMEYTNA  703
            R +++           K   ++N   L+ V ++++K++TE+ ++M+FNT IA+LM     
Sbjct  666  RLITT-----------KEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMV----  710

Query  704  LSKYINEDNKNSKFLKECVEDFIILIAPFAPHFSEEQWELLGMTYSVFN-EKWPQFDSKA  762
               ++N  NK+ K++ +   +F+ LIAPFAPH++EE W+ L  +   ++   WP +D   
Sbjct  711  ---FVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESK  767

Query  763  LVKDEIEIAVQVNGKIRDRITIASGLDEESIKETALNSEDVKKYTDGknivkiiiikGRL  822
            LV +++EI VQ++GK++ ++ +A +L  E ++E AL +E V+    GK+I+K+I +  +L
Sbjct  768  LVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKL  827

Query  823  VNIVVK  828
            VNIV+K
Sbjct  828  VNIVIK  833

742) Clopa_1241 in NC_021182


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  598 bits (2260),  Expect = 4e-172, Method: Compositional matrix adjust.
 Identities = 386/843 (46%), Positives = 558/843 (67%), Gaps = 56/843 (6%)

Query  6    TKIDEKWQKIWEDKSLYKFDENNMGKKLYALEMFSYPSGARLHAGHWFNYGPVDSWARFK  65
            T I+ KWQ +W D+  +K + +    K+YAL+MF+YPSGA LH GH   Y + D  +RFK
Sbjct  7    TAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSRFK  66

Query  66   KMQGYNVFQPMGFDAFGLPAENYAIKTGVHPKDSTIKNIETMEKQLKAMGAMFNWDHEVV  125
            + QG NV++PMG DAFGLPAE+YA+ TG +P + T  NI    +Q++A+G  ++WD+EV 
Sbjct  67   RAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDREVN  126

Query  126  TCFPDYYKWTQWLFLKLYEKGLAYRKKAPVNWCPSCNTVLANEQVV-DGGCERCGTEVVK  184
            T  P+YYKWTQW+F KLYEKGLAY    PVNW     T +ANE+V+ DG  ER G  VV+
Sbjct  127  TTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVR  186

Query  185  KDLTQWFLKITDYSEELLQKLDDLDWPEKTKAMQRHWIGKSKGAEATFKVDNSdvtfdvf  244
            K + QW LKIT Y+E LL+ L+++DWPE  K MQR+WIGKS GA+ TFKV ++D  F VF
Sbjct  187  KPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVF  246

Query  245  ttrvdtlfGVTYVVLAPESPLTDKVTTTEHIEAVEEYKTQSAKQSDIERQSLTREKTGVF  304
            TTR DTLFG TY VLAPE +L D +TT+++ EAV +YK Q++ +SD+ R  L++EKTGV 
Sbjct  247  TTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVW  306

Query  305  TGSYAINPVNGKKVPIWVADYVLATYGTGAVMAVPSHDERDFAFATKYNLPIIRVVEGG-  363
            TGSYAINPVNGK +P+W+ADYVLA+YGTGA+MAVP+HDERD  FA ++NL II V+EGG 
Sbjct  307  TGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGN  366

Query  364  -DSLPYTDYGKLVNSSEFDGLSGNEAKEAIVKLLSSKNLGHWKVNYRLRDWLVSRQRYWG  422
             +  ++T+ G  +NS  +DGL    A   +V  L +  +G+ +V YRLRDWL SRQRYWG
Sbjct  367  VEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWG  426

Query  423  APIPIVYCEKCGIVPVPEDQLPVELPYDVEFAPDGR--SPLAKSEEFVNTTCPHCGGPAK  480
             PIPI+  E     +VPE +LP+ LP   ++ P G   SPLA+  + ++ T  + G  ++
Sbjct  427  EPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED-GVKGR  485

Query  481  REVDTLDTFVCSSWYYLRYPDSKNSDKAFDPEIINKMLPVDKYVGGPEHACMHLLYARFI  540
            RE +T+     SSWYYLRY D+ N++K  D E++++ LPVD YVGG+EHA +HLLYARF 
Sbjct  486  RETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFW  545

Query  541  TKALRDMGYLNFDEPFLSLRHQGLILGP--------------------------------  568
             K L D+G +   EPF  L +QG+ILG                                 
Sbjct  546  HKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEELE  605

Query  569  -DGQKMSKSKGNTISPDDYIKEYGADVFRLYLMFGFDYTEGGAWSDDGIKAISKFVDRVE  627
                KMSKS  N ++PDD + +YGAD +R+Y MF      + AWS++G+ +  KF+DRV 
Sbjct  606  QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVY  665

Query  628  RILSQCTEASADKTTIDKAEKELNYVRNFVIKSVTEDAEKFQFNTCVARIMEFTNALSKY  687
            R+++    +  +  ++DK  +E        +K+VTE+ ++ +FNT +A++M F NA    
Sbjct  666  RLITTKEITEENSGALDKVYNE-------TVKAVTEQVDQMKFNTAIAQLMVFVNA----  714

Query  688  LNEEKKNTELLKQCVNDFIRILSPFAPHFSEEMW--LNTGNNFSVFKEAWPNFDPKALIK  745
                +K+  L+ +  ++F+++++PFAPH++EE+W  L ++ +   +  +WP++D   L+ 
Sbjct  715  ---ANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISY-VPWPSYDESKLVE  770

Query  746  DEVEIAIQVNGKIKARIDIASDLKEDAIKETALKDDNVKAAIEGKNVIKVIVIKGRLVNI  805
            ++VEI +Q++GK+KA++ +A DL  + ++E AL +++V+A I GK++IKVI +  +LVNI
Sbjct  771  NDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNI  830

Query  806  VAK  808
            V K
Sbjct  831  VIK  833

743) Osc7112_1185 in NC_019729


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  598 bits (2259),  Expect = 5e-172, Method: Compositional matrix adjust.
 Identities = 369/869 (43%), Positives = 579/869 (67%), Gaps = 47/869 (5%)

Query  5    YNPQSIEEKWQQAWAEQNLDQMPEDTQKPKFYALSMFPYPSG-NLHMGHVRNYTIIDVIA  63
            Y+  +IE KWQ  WA+++  +   D+ KPKFYAL MFPYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RLKRMQGYRVLNPMGWDAFGLPAENAAIERGIPPAQWTYQNIAQMKGLFRRLGISFDWTK  123
            R+KR QG  VL+PMGWDAFGLPAE+ A++ G  PA+ T +NIA+ K  +  LG+S+DW +
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVTTCSPDYYRWTQWIFLQFLEAGLAYQKEAAVNWDPIDQTVLANEQVDNEGRSWRSGAK  183
            EV T  P+YY+WTQWIF ++ E GLAY+ E +VNW     T +ANE+V  +G S R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  184  VERKLLRQWFLKITDYAEQLLNDLDKLPDWPERVKLMQANWIGKSVGAYLEFPIVGMDEK  243
            V RK +RQW LKIT YAE+LL+DL+ + DWPE +K MQ NWIGKS GA + F + + D  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  244  IAVFTTRPDTVYGVSYLVLAPEHPLTQRVTTEDRKAAVETFIKEVAAQSEIDRTAEDKPK  303
            ++VFTTRPDT++G +Y VLAPEH+L + +TT D+  AV  + ++ + +S++ RT   K K
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEK  302

Query  304  RGIPTGGKAINPFNGEEIPIWIADYVLYEYGTGAVMGVPAHDTRDFKFANQYQLPIKVVI  363
             G+ TG+ AINP NG E+P+WIADYVL  YGTGA+M+VPAHD RD  FA+Q++L I + +
Sbjct  303  TGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDI-IPV  361

Query  364  VDDDEIPLTEAYTEAGIMINSESFNGMDSIKGKAAIIHHAENAGYGKARIQYRLRDWLIS  423
            ++++++    A+TE G+ INS+ ++G+D   + A +++  E  G G+  + YRLRDWL+S
Sbjct  362  LEGGNVE-EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  424  RQRYWGAPIPVIHCPNCGTVPVPQSDLPVLLPENVEFTGKG---SPLAKMEEWVNVPCPS  480
            RQRYWG PIP+IH  +  + +VP+S+LP++LP   ++   G   SPLA++ +W++V    
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  481  CGTPAKRETDTMDTFIDSSWYFLRYPDAQNQQQVFDSAKTNDWMPVDQYVGGIEHAILHL  540
             G  ++RET+TM    +SSWY+LRY D++N +++ D    ++W+PVD YVGG EHA+LHL
Sbjct  481  -GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHL  539

Query  541  LYSRFFTKVLRDRGLIDCDEPFKRLLTQGMVQAMAYKNPVTGKYVPPADIDPANPK--DP  598
            LY+RF  KVL D G++   EPF++L+ QGM+ + +Y+++  G  V+   ++  +    + 
Sbjct  540  LYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDS-RGALVATDKVEKRDGSFFHV  598

Query  599  QTGEVLEVFYEKMSKSKYNGVDPLEVMGKYGVDTARMFILFKAPPEKDLEWDDADVEGQF  658
            +TGE LE    KMSKS  N V+P +V+ +YG DT R++ +F +P +  + W + ++EG  
Sbjct  599  ETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSR  658

Query  659  RFLNRVWRLVTEFCGAGILPATEVPGTGGTPIPQLNSPDNLESQNLSKIEKDLRRAIHTA  718
            +FL+RV RL+T         + E+    + +                     L +  + +
Sbjct  659  KFLDRVYRLIT---------TKEITEENSGA---------------------LDKVYNET  688

Query  719  IKEVSDDLEGDYQFNTAVSEMMKLSNALNDAKCKNSPIYAEGINTLIRLLAPFAPHIADE  778
            +K V+++++ + +FNTA++++M + NA N    K+  ++++  + +++L+APFAPH+++E
Sbjct  689  VKAVTEQVD-QMKFNTAIAQLMVFVNAAN----KEDKLFSDYAKGFVQLIAPFAPHLGEE  743

Query  779  LWHN-TGNSESVHVQTWPTVDPSALVTDEITLVIQVMGKTRGTIQVPSGADKAALEKFAR  837
            LW+  T+++ES+    WP+ D S LV +++ +V+Q+ GK ++ + V+ +  +  L+  A 
Sbjct  744  LWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVAL  803

Query  838  ESELAKRHLEGKEIKKVIVVPGKLVNFVV  866
             +E  + ++ GK+I KVI VP KLVN+V+
Sbjct  804  ANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

744) Mic7113_0700 in NC_019738


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  598 bits (2257),  Expect = 7e-172, Method: Compositional matrix adjust.
 Identities = 378/856 (45%), Positives = 575/856 (68%), Gaps = 33/856 (3%)

Query  5    YNPAEIEAHWQKIWSEQGIDQTQTESDKPKFYALSMFPYPSG-NLHMGHVRNYTITDVIA  63
            Y+ + IE+ WQ +W+++   +T T++ KPKFYAL MFPYPSG  LH+GH   YT TD+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RTHRMQGYRVLHPMGWDAFGLPAENAAIQRGVHPAKWTYENIAHMKGQLKPLGFSIDWNH  123
            R  R QG  VLHPMGWDAFGLPAE+ A++ G +PA  T ENIA+ K Q+++LGFS DW++
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCSPDYYKWTQWIFLQFLKAGLAYQKEAAVNWDPIDQTVLANEQVDSEGRSWRSGAK  183
            E+ T  P+YYKWTQWIF ++   GLAY+ E +VNW     T +ANE+V ++G S R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  184  VERKLLRQWFFKITNYAEELLNDLDKLTGWPERVKLMQANWIGKSVGAYLEFPIVGMDEK  243
            V RK +RQW +KIT YAE LL+DL+ + +WPE +K MQ NWIGKS GA + F + + D  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  244  IGVFTTRPDTVYGVTYVVLAPEHPLTPKVTTQDRKVAVDAFIQEVSEESELERTAEDKPK  303
            + VFTTRPDT++G TY VLAPEH+L   +TT D+  AV  + ++ S  S+L RT   K K
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEK  302

Query  304  RGIPTGGKAINPFTGEEIPIWIADYVLYEYGTGAVMGVPAHDTRDFQFATEQKLPIQVAI  363
             G+ TG+ AINP  G E+P+WIADYVL  YGTGA+M+VPAHD RD +FA + +L I +++
Sbjct  303  TGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDI-IPV  361

Query  364  VRADAADAKVAPKQAYTEPGIVVNSDLFNGMESPHAKEEIIKYAERQGWGKARIQYRLRD  423
            + ++  +       A+TE G+ +NSD+++G++ + A   ++   E +G G+  + YRLRD
Sbjct  362  LEGGNVEE-----AAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  424  WLISRQRYWGAPIPVIHCPNCGIVPVPEADLPVQLPEDVEFK--GGRVSSLAQLEGWANV  481
            WL+SRQRYWG PIP+IH  +    +VPE++LP+ LP   +++  G   S+LA++ +W +V
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  482  PCPSCGTAAKRETDTMDTFIDSSWYFLRFTDAKNDNQVFDPNKTNDWMPVDQYVGGIEHA  541
                 G  ++RET+TM    +SSWY+LR+ D+ N +++ D +  ++W+PVD YVGG EHA
Sbjct  477  TRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  542  ILHLLYSRFFTKVLRDRGLLNFDEPFQRLLTQGMVQGLTYMNPTTGKWIPSAQVDPNDPK  601
            +LHLLY+RF  KVL D G++   EPFQ+L+ QGM+ G +Y ++  +  +++ +V+  D  
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGAL-VATDKVEKRDGS  594

Query  602  --DPETGEKLEVSYKTMSKSKYNGVAPEAVINKYGADTARMFILFKAPPEKDLEWDEADV  659
              + ETGE LE +   MSKS  N V P+ V+++YGADT R++ +F +P +  + W E ++
Sbjct  595  FFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGL  654

Query  660  EGQFRFLNRVWRLVTDFVAVKGAKPNTPTEGDLTKAEKDLRRAIHTAIKAVTEDLGDEYQ  719
            EG  +FL+RV RL+T       +K  T  +++       L +  + ++KAVTE++ D+ +
Sbjct  655  EGSRKFLDRVYRLIT-------TKEITEENSG------ALDKVYNETVKAVTEQV-DQMK  700

Query  720  FNTAVSELMKLSNALTDANCKDSPVYVEGIETLILMLAPFAPHIAEELWRQ-TGHSESVH  778
            FNTA+++LM     + +A  K+  ++ +    ++ ++APFAPH++EELW+  T+ +ES+ 
Sbjct  701  FNTAIAQLM----VFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESIS  756

Query  779  TAPWPQYDPDALVADEITLVIQIMGKTRGTVQVPSQADKQALEQYARESEVAQRYLEGKE  838
              PWP YD   LV +++ +V+QI GK ++ + V+ +  ++ L++ A  +E  Q  + GK+
Sbjct  757  YVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKD  816

Query  839  IKKVIVVPGKLVNFVV  854
            I KVI VP KLVN+V+
Sbjct  817  IIKVIAVPNKLVNIVI  832

745) Amet_2314 in NC_009633


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  598 bits (2257),  Expect = 8e-172, Method: Compositional matrix adjust.
 Identities = 388/866 (45%), Positives = 574/866 (67%), Gaps = 75/866 (8%)

Query  1    MAIYDFGNIEKKWQERWQENKAFSI-IERDRPKYYVLEMFPYPSGK-IHMGHVRNYSIGD  58
            M++YD   IE KWQ  W +N +F    +  +PK+Y L+MFPYPSG  +H+GH   Y+  D
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  59   VVARFKRMKGYNVLHPMGWDSFGLPAENAAIKHGIHPDHWTKENVKEMKEQLDALGLSYD  118
            +++RFKR +G NVLHPMGWD+FGLPAE+ A+  G +P + T EN+ + K Q++ALG+SYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  119  WDREVSTCTPEYYKWTQWLFLQFYHKGLAYKKESQVNWCPSCETVLANEQVV-NGGCDRC  177
            WDREV+T  P+YYKWTQW+F ++Y+KGLAY  E  VNW     T +ANE+V+ +G  +R 
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  178  DSSVGKKNLNQWYFKITDYAEALLEDIKLLDGWPEKVKTMQQNWIGKSHGAEIDFPIENT  237
            + +V +K + QW +KIT YAE LLED+  +D WPE +K MQ+NWIGKS GA++ F + +T
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDT  239

Query  238  SKELKVFTTRPDTIYGATYMVLAPEHPYVMELVKETEYEEAVVAFRNKLQHMSDIERTST  297
             K++ VFTTRPDT++GATY VLAPEH+ +++ +  ++  EAV  ++ +    SD+ RT  
Sbjct  240  DKDFTVFTTRPDTLFGATYAVLAPEHA-LVDAITTSDQAEAVADYKRQASLKSDLARTDL  298

Query  298  EIEKEGIFIGKYCINPVSNEKIPIYIANYVLADYGTGAIMAVPAHDQRDLDFARKYDITV  357
              EK G+  G Y INPV+   +P+ IA+YVLA YGTGAIMAVPAHD+RD +FA+++++ +
Sbjct  299  AKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDI  358

Query  358  TPVIRPIDESDGFDIEKEAYTDSGIMINSEKFNGLDSEKAYEDIAKHIETLNAGKRTINY  417
             PV+      +G ++E  A+T+ G+ INS+ ++GLD   A   +   +E+   G+  + Y
Sbjct  359  IPVL------EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTY  412

Query  418  RLRDWLLSRQRYWGTPIPIIYCDDCGIVPVREEELPVKLPV--DVTFSGKGSSPLETSEG  475
            RLRDWL+SRQRYWG PIPII  +D    +V E ELP+ LPV  D+  SG G SPL    +
Sbjct  413  RLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTD  472

Query  476  FLNTNCPSCGKMAKRETDTMDTFVDSSWYFLRYTDANNEQLPFSKEAANYWVPVDQYIGG  535
             L+       K ++RET+TM    +SSWY+LRY D++N +     E  + W+PVD Y+GG
Sbjct  473  WLEVTREDGVK-GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGG  531

Query  536  VEHAILHLLYSRFFTKVMKDLGLTDQPEPFKKLLTQGMVL-------------------K  576
             EHA+LHLLY+RF  KV+ DLG+    EPF+KL+ QGM+L                   +
Sbjct  532  AEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKR  591

Query  577  DG---------------AKMSKSKGNVVSPEEIIQKYGADTARLFVLFAAPPERDLEWSD  621
            DG               AKMSKS  NVV+P++++++YGADT R++ +F +P +  + WS+
Sbjct  592  DGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSE  651

Query  622  QGVEGSYRFLNRVWRL--AEEFIDNNLFMSTSLGEALTKRDKDLKYTIHYTIKKVTSDVE  679
            +G+EGS +FL+RV RL  + E+ ++N       + AL K  ++       T+K VT +V 
Sbjct  652  EGLEGSRKFLDRVYRLITTKEITEEN-------SGALDKVYNE-------TVKAVTEQV-  696

Query  680  DRFNFNTAISAVMELINELYKYKETDPSKLNGDLFREGIETSILLLAPFAPHFTEELWEK  739
            D+ +FNTAI+ +M ++N         +++ ++ LF +     + L+APFAPH+ EELW+ 
Sbjct  697  DQMKFNTAIAQLMVFVN---------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  740  L-GKAESVHMTNWPEYDHEAIIKDEVEIVMQVNGKVKDRMMVPTNVSKEELESLAMKNek  798
            L + +ES+    WP YD+  ++ ++VEIV+Q++GKVK +++V+ ++S+EEL+ +A+ NEK
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  799  iiqiiegkqiikiiAVPKKLVNIVIK  824
            +   I GK+IIK+IAVP+KLVNIVIK
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVIK  833

746) Riv7116_4568 in NC_019678


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  597 bits (2255),  Expect = 1e-171, Method: Compositional matrix adjust.
 Identities = 382/856 (45%), Positives = 565/856 (67%), Gaps = 33/856 (3%)

Query  5    YNPAEIELHWQNKWAEMGLDKTLKDSSKPKFYALSMFPYPSG-NLHMGHVRNYTITDVIA  63
            Y+ + IE  WQ  WA+    KT  D+SKPKFYAL MFPYPSG  LH+GH   YT TD+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RLKRMQGYRVLHPMGWDAFGLPAENAAIKRGVPPSKWTYQNIEQMRGQLKRLGLSIDWDC  123
            R+KR QG  VLHPMGWDAFGLPAE+ A+  G  P+  T +NI + + Q++ LG+S DWD 
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVATCSADYYKWTQWIFLQFFQAGLAYQKEAAVNWDPIDQTVLANEQVDSEGRSWRSGAI  183
            EV T  ++YYKWTQWIF ++++ GLAY+ E +VNW     T +ANE+V ++G S R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  184  VERKLLRQWFFKITDYAEELLTDLDKLSGWPDRVKTMQANWIGKSTGAYLEFPIVGMDQK  243
            V RK +RQW +KIT YAE LL DL+ + +WP+ +K MQ NWIGKSTGA + F + + D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  244  IGVYTTRPDTVYGVSYVVLAPEHPLTKQVTTPEQKAAVEAFVQEVGNQSELERTAEDKPK  303
            + V+TTRPDT++G +Y VLAPEH+L   +TT++Q  AV  + ++ + +S+L RT   K K
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEK  302

Query  304  RGMSTGGKAINPFTGEEIPIWIADYVLYEYGTGAVMGVPAHDVRDFKFAGEKNLPIKFVV  363
             G+ TG+ AINP  G E+P+WIADYVL  YGTGA+M+VPAHD RD  FA + NL I   +
Sbjct  303  TGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDI---I  359

Query  364  APTDNSVETEKAYTEPGILVNSSQFDGMQSTEAKQAIVEYAQKQGFGQARVQYRLRDWLI  423
            +  + +   E A+TE G+ +NS  +DG++ + A   +VE  + +G G+  V YRLRDWL+
Sbjct  360  PVLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLF  419

Query  424  SRQRYWGAPIPIVHCSDCGAVPVPDKDLPIELPENVEF--SGRGGSPLAQLESWVNVDCP  481
            SRQRYWG PIPI+H  D  + +VP+ +LP+ LP   ++  SG G SPLA++  W++V   
Sbjct  420  SRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRE  479

Query  482  SCGKPAKRETDTMDTFIDSSWYYLRFTDAKNDNQVFDSAKVNDWMPVNQYVGGIEHAILH  541
               K ++RET+TM    +SSWYYLR+ D+ N +++ D   +++W+PV+ YVGG EHA+LH
Sbjct  480  DGVK-GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLH  538

Query  542  LLYSRFFTKVLRDRGLLNFDEPFQHLLTQGMVQGLTYTNPNKAGKDKWVASNLVDAANPR  601
            LLY+RF  KVL D G++   EPFQ L+ QGM+ G +Y    + +++  VA++ V+  +  
Sbjct  539  LLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY----RDSRGALVATDKVEKRDGS  594

Query  602  --DPETGEPLQQVYATMSKSKGNGVAPEDVIAKYGVDTARMFVLFKAPPEKDLEWDEADV  659
              + ETGE L+Q  A MSKS  N V P+DV+ +YG DT R++ +F +P +  + W E ++
Sbjct  595  FFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGL  654

Query  660  EGQFRFLNRVWRLVTDFAnnpqsskkskqnnpkskIEKDLRRAIHTAIKEVGEDVDSDYQ  719
            EG  +FL+RV RL+T              ++        L +  + ++K V E+VD + +
Sbjct  655  EGSRKFLDRVYRLITT-------------KEITEENSGALDKVYNETVKAVTEQVD-QMK  700

Query  720  FNTAISELMKLSNALNDAKCKDSPIYAEGINTLVSMLAPFAPHIAEELWH-LLGNHNSVH  778
            FNTAI++LM + NA N    K+  ++++  + +V ++APFAPH++EELW+ L ++ +S+ 
Sbjct  701  FNTAIAQLMVFVNAAN----KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESIS  756

Query  779  TANWSKHDPEALIADEITLVIQINGKKRGDLQVPAQLDKAGLEKYARSSEVAQRHTENKT  838
               W+  D   L+ +++ +V+QI+GK ++ L V+ +L +  L+  A ++E  Q +   K 
Sbjct  757  YVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKD  816

Query  839  IKKVIVVPGKLVNFVI  854
            I KVI VP KLVN+VI
Sbjct  817  IIKVIAVPNKLVNIVI  832

747) MROS_1551 in NC_018178


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  597 bits (2255),  Expect = 1e-171, Method: Compositional matrix adjust.
 Identities = 377/858 (44%), Positives = 554/858 (65%), Gaps = 67/858 (7%)

Query  3    YPFESIELKWQKYWKDKKVFKTDLTKIDNKLYVLVMFIYPSAAKMHIGHWYNYGPTDSFA  62
            Y   +IE KWQ +W D+  FKT+      K+Y L MF YPS+A +H+GH   Y +TD ++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKKLKGFNVFEPMGYDAFGLPAENYAIKTGIHPQDSTLKNIKDIRSMLDRMGGMYDWDA  122
            R+K+ +G NV++PMG DAFGLPAE+YA+ TG +P + T  NI +++  ++ +G  YDWD 
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  ELMTCVPEYYKWNQWLFLQLYKKGLAYRKNAPVNWCPSCQTVLAREQVLGDGGCERCGTT  182
            E+ T  P+YYKW QW+F +LY KGLAY  + PVNW     T +A E+VL DG  ER G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VIQKNLTQWFFKITEYADELLDGLNKIDWPEKTKTMQINWIGKSYGTEIDFSIEGSDEKI  242
            V++K + QW +KIT YA+ LL++L+ +DWPE  K MQ NWIGKS G+++ F + ++D  +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  243  RVFTTRPDTLFGVTYVVLAPENELVQKITKPEYKDAVDKYIESIKSLTEVERTSTTKEKT  302
             VFTTRPDTLFG TY VLAPE+ LV+ IT ++  +AV  Y       +++ RT  +KEKT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  303  GVPTGAYAINPINGEKVPIWIADYVLATYGTGCVMAVPGHDERDFEFAKKFNLPIKKVIL  362
            GV TG+YAINP+NG  +P+WIADYVLA+YGTG +MAVP+HDERD EFAK+FNL I  V L
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV-L  362

Query  363  QPGTNEEDELKEAYTDVGVMINSGKYNGLSSDVGIEKISEDIEKQGLGKRTVNYRLRDWL  422
            + G  EE     A+T+ G+ INS+  +GL    +I K+ E +E +G+G+  V YRLRDWL
Sbjct  363  EGGNVEE----AAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWL  418

Query  423  ISRQRYWGTPIPVIHCDKCGEVPVPEDQLPVVLPYEVNFKPDGG--SPLASCEEFINTTC  480
            +SRQRYWG PIP+IH +     +VPE +LP+VLP   +++P G   SPLA+  + ++ T 
Sbjct  419  FSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTR  478

Query  481  PECGAPARRDPDTMDTFVDSSWYYLRYLNPRYEEGMFDSELANNWVPVDVYVGGAEHATM  540
             + G  +RR+ +TM    +SSWYYLRY++P+  E + D EL ++W+PVD+YVGGAEHA +
Sbjct  479  ED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVL  537

Query  541  HLLYARFIHKFLRDIGLVNSDEPFQKLIHQGTI---------------------------  573
            HLLYARF HK L D+G+V + EPFQKL++QG I                           
Sbjct  538  HLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFH  597

Query  574  -------TNQGAKMSKSKGNVVDPNEFLEKYGSDVFRMYLMFMGPYELGGDWSDKGIVGV  626
                    +  AKMSKS  NVV+P++ +E+YG+D +R+Y MFMGP + +  WS+ G+ G 
Sbjct  598  VETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGS  657

Query  627  DRFVQRTYTLFENYRGIASDTHAKSKYDMNELSDDEKKIYQKV-NQTLAKVDSEIDNFRF  685
             +F++R Y L+                  +E+++++    +KV N+T+  V  ++D+ +F
Sbjct  658  RKFLDRVYRLITT----------------KEITEENSGALDKVYNETVKAVTEQVDQMKF  701

Query  686  NTAVAALMELLNELKNIDNCRKEIQVYT--LERFASMLAPLAPHLGEECWSLLGKEKSIY  743
            NTA+A LM +      ++   KE ++++     F  ++AP+APHLGEE W  L       
Sbjct  702  NTAIAQLMVF------VNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESI  755

Query  744  EKPVWFEPDAEALINEtvtvvvqvNGKVRAKIELPVDTPEREVKNIVFNDDKIKGYVDGK  803
                W   D   L+++ V +VVQ++GKV+AK+ ++ D +  E++++ + ++K+++ + GK
Sbjct  756  SYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGK  815

Query  804  QIVKEIYVPNKIYNIVVK  821
            +I+K I VPNK+ NIV+K
Sbjct  816  DIIKVIAVPNKLVNIVIK  833

748) Aazo_4197 in NC_014248


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  597 bits (2256),  Expect = 9e-172, Method: Compositional matrix adjust.
 Identities = 382/858 (45%), Positives = 575/858 (68%), Gaps = 33/858 (3%)

Query  7    TLYHPATIEEKWQKIWSELGLDKTPQYHNQPKFYALSMFPYPSGR-LHMGHVRNYTITDV  65
            T+Y+ ++IE KWQ +W++    KT    ++PKFYAL MFPYPSG  LH+GH   YT TD+
Sbjct  2    TFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDI  61

Query  66   IARLKRMQGYLVLHPMGWDGFGLPAENAAIDRGVPPAKWTYQNIEQMRQQLQRLGLSLDW  125
            ++R+KR QG  VLHPMGWD+FGLPAE+ A+D G  PA  T +NI + ++Q++ LG+S DW
Sbjct  62   LSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDW  121

Query  126  ECELATCSPDYYKWTQWIFLQLLAAGLAYQREAAVNWDPIDQTVLANEQVDNEGRSWRSG  185
            + E+ T  P+YYKWTQWIF +L   GLAY+ E +VNW     T +ANE+V  +G S R+G
Sbjct  122  DREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGG  181

Query  186  AIVERKLLRQWFFRITDYAEELLNDLDKLTGWPERVKLMQANWIGKSIGAYLEFPIVGLD  245
              V RK +RQW ++IT YAE LL+DL+ + +WPE +K MQ NWIGKS GA + F + + D
Sbjct  182  YPVVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  246  EKIGVYTTRPDTIYGVSYVVLAPEHPLTQVVTTSEQKSVVEAFIKEITNQSELERTAEDQ  305
              + V+TTRPDT++G +Y VLAPEH+L + +TTS+Q   V  + ++ + +S+L RT   +
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  306  PKRGIPTGGKAINPFTGEEVPIWIADYVLYEYGTGAVMGVPAHDVRDFKFAKEQNLAIKF  365
             K G+ TG+ AINP  G E+P+WIADYVL  YGTGA+M+VPAHD RD  FAK+ NL    
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLD---  357

Query  366  VIVPEVGADETLKAAYTEVGILVNSGDFNGMNSIDAKKAIVEFAEKQNFGKLRVQYRLRD  425
             I+P + +++   AA+TE G+ +NS+ ++G++   A   +VE  E +  G+  V YRLRD
Sbjct  358  -IIPVLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  426  WLISRQRYWGAPIPVIHCPNCGVMPVPDKDLPVQLP--EEIELSGRGGSPLAQLESWVNV  483
            WL+SRQRYWG PIP+IH  +    +VP+ +LP+ LP   +I  SG G SPLA++  W++V
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  484  PCPSCGTPAKRETDTMDTFIDSSWYFLRYPDVKNEEKIFDSNKVNYWMPVDQYVGGIEHA  543
                 G  ++RET+TM    +SSWY+LRY D  N EK+ D + ++ W+PVD YVGG EHA
Sbjct  477  TRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  544  ILHLLYSRFFTKVLRDRGLFNFDEPFQKLLTQGMVKGLTYMNPKKYGKDKWIPSHLVDAN  603
            +LHLLY+RF  KVL D G+    EPFQKL+ QGM+ G +Y +    +++  ++++ V+  
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRD----SRGALVATDKVEKR  591

Query  604  NPV--DPQTGEPLKRLYATMSKSKGNGVAPEDVINKYGIDTARMFILFKAPPEKDLEWDE  661
            +    + +TGE L +  A MSKS  N V P+DV+++YG DT R++ +F +P +  + W E
Sbjct  592  DGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSE  651

Query  662  ADVEGQFRFLNRVWRLVTNYAAAGVCKQKSELDKLSKGEKDLRRAIHIAIQAITEDVGDE  721
             ++EG  +FL+RV RL+T   +  +  ++S           L +  + +++A+TE+V D+
Sbjct  652  EGLEGSRKFLDRVYRLIT---TKEITEENSG---------ALDKVYNETVKAVTEQV-DQ  698

Query  722  YQFNTAISELMKLSNALTDASCNNSPIYAEGIQTLVIMLAPFAPHIGDELWQ-LLGNKNS  780
             +FNTAI++LM     + +A+ ++  ++++  + +V ++APFAPH+G+ELWQ L ++ +S
Sbjct  699  MKFNTAIAQLM----VFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGES  754

Query  781  VHTRTWPSFDPAALIADEITVVIQIMGKTRGSIQVPSHLDKAELEKYALESEVAQRYIEG  840
            +    WPS+D + L+ +++ +V+QI GK ++ + V+ +L + EL+  AL +E  Q  I G
Sbjct  755  ISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAG  814

Query  841  KEIKKAIIVPGKLVNFVL  858
            K+I K I VP KLVN+V+
Sbjct  815  KDIIKVIAVPNKLVNIVI  832

749) leuS in NC_009925


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  596 bits (2252),  Expect = 2e-171, Method: Compositional matrix adjust.
 Identities = 389/855 (46%), Positives = 564/855 (66%), Gaps = 32/855 (3%)

Query  5    YNPTEIEPKWQASWAKQGLDATPEDTSKPKFYALSMFPYPSGS-LHVGHTRNYVITDVIA  63
            Y+ T IEPKWQA WA +    T  D+SKPKFYAL MFPYPSG+ LHVGH   Y  TD+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RLKRMQGYRVLQPMGWDAFGLPAENAAIARGIHPAEWTYANMAQMKKQLEPLGLSIDWSR  123
            R+KR QG  VL+PMGWDAFGLPAE+ A+  G +PAE T  N+A+ K+Q+++LG+S DW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EIATCSPDYYRWTQWIFLQFLDMGLAYQKEAAVNWDPVDQTVLANEQVDNEGRSWRSGAK  183
            E+ T  P+YY+WTQWIF ++ + GLAY+ E +VNW     T +ANE+V  +G S R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  184  VERKLLRQWFLKITDYAEELLTDLDKLTGWPERVKTMQANWIGKSVGAYLEFPIVGMDEK  243
            V RK +RQW LKIT YAE LL DL+ + +WPE +K MQ NWIGKS GA + F + + D  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  244  VAVFTTRPDTVYGVTYVVLAPEHPLTPQVTSKAQKKAVDKFIEAVGAESEMDRTAEDKPK  303
             +VFTTRPDT++G TY VLAPEH+L   +T+  Q  AV  +    +  S++ RT   K K
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEK  302

Query  304  KGIPTGGKAINPFTGEEIPIWIADYVLYEYGTGAVMGVPAHDTRDFVFAQQNKLPIQTVI  363
             G+ TG+ AINP  G E+P+WIADYVL  YGTGA+M+VPAHD RD  FA+Q +L I  V+
Sbjct  303  TGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL  362

Query  364  VPEGGDAETPLEAAYTEPGLMVNSGEFDGKVSTEGKQAIIAKAETKGWGKARVQYRLRDW  423
              EGG+ E   EAA+TE GL +NS+ +DG   + +   ++   E+ G G+  V YRLRDW
Sbjct  363  --EGGNVE---EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDW  417

Query  424  LISRQRYWGVPIPVIHCPNCGAVPVPEADLPVELP--EDVEFSAQGGSPLAKLESWVNVA  481
            L+SRQRYWG PIP+IH  +  + +VPE++LP+ LP   D+  S+ G SPLA++  W++V+
Sbjct  418  LFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT  477

Query  482  CPNCGADAKRETDTMDTFIDSSWYFLRYPDAKNDKAVFDSAKTNDWLPVDQYVGGIEHAI  541
              + G  ++RET+TM    +SSWY+LRY D+ N   + D    ++WLPVD YVGG EHA+
Sbjct  478  RED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  542  LHLLYSRFFTKVMRDRKLLNFDEPFKKLLTQGMVQALTYKNPETGQYIAPINVDADDPK-  600
            LHLLY+RF  KV+ D  ++   EPF+KL+ QGM+ + +Y+++  G  +A  +V+  D   
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDS-RGALVATDKVEKRDGSF  595

Query  601  -DPETGAPLEAFYEKMSKSKYNGVPPEEVTNKYGADTARLFTLFKAPPEKDLEWEGADVE  659
             + ETG  LE    KMSKS  N V P++V ++YGADT R++ +F +P +  + W   ++E
Sbjct  596  FHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLE  655

Query  660  GQFRFLNRVWRLVSEHaaqakgkkakvnkaklskTEKELRRSIHIAIKETSEDLDGDYQF  719
            G  +FL+RV RL++                        L +  + ++K  +E++D + +F
Sbjct  656  GSRKFLDRVYRLITTK-------------EITEENSGALDKVYNETVKAVTEQVD-QMKF  701

Query  720  NTAVSELMKLSNALSDSKEKASPVYAEGVETLLLLLTPFAPHISEELWENL-GHSESILG  778
            NTA+++LM     + ++ +K   ++++    ++ L++PFAPH++EELW+ L + +ESI  
Sbjct  702  NTAIAQLM----VFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISY  757

Query  779  QTWPQVDEEALVADEITLVIQIMGKTRGTIQVPAGSSREDLEQLARESEVAQRYIAGKEV  838
              WP  DE  LV +++ +V+QI GK ++ + V+ + SRE+L+++A  +E  Q  IAGK++
Sbjct  758  VPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDI  817

Query  839  KKVIVVPGKLVNFVV  853
             KVI VP KLVN+V+
Sbjct  818  IKVIAVPNKLVNIVI  832

750) PCC7418_1974 in NC_019779


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  596 bits (2252),  Expect = 2e-171, Method: Compositional matrix adjust.
 Identities = 379/854 (45%), Positives = 573/854 (68%), Gaps = 31/854 (3%)

Query  7    YNPADIEPKWQQYWLETKADEADEDQSKPKFYALSMFPYPSG-NLHMGHVRNYVITDVMA  65
            Y+ + IEPKWQ +W +  +  ++ D SKPKFYAL MFPYPSG  LH+GH   Y  TD+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  66   RWRGMQGYRVLHPMGWDAFGLPAENAAIDRGVHPAQWTnqniqqmkkqlqqlGLSLDWSR  125
            R +  QG  VLHPMGWDAFGLPAE+ A+D G +PA+ T +NI + K+Q++ LG+S DW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  126  EVATCSPDYYKWTQWIFLQFFQGGLAYQKESAVNWDPIDQTVLANEQVDGEGRSWRSGAK  185
            EV T  P+YYKWTQWIF ++++ GLAY+ E +VNW     T +ANE+V  +G S R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  186  VERKLLKQWFLKITEYAEELLNDLEKLSGWPDRVKLMQENWIGKSVGAYLEFPIIGREDK  245
            V RK ++QW LKIT YAE LL+DLE + +WP+ +K MQ NWIGKS GA + F + + +  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  246  IGVFTTRPDTVYGVTYVVLAPEHPLTPQVTTTDQKEAVEAFIEEVSNESELERTAEDKPK  305
            + VFTTRPDT++G TY VLAPEH+L   +TT+DQ EAV  +  + S  S+L RT   K K
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEK  302

Query  306  RGIPTGGKAVNPFTGEEIPILIADYVLYEYGTGAVMGVPAHDARDFQFASQNQLPIKQVI  365
             G+ TG+ A+NP  G E+P+ IADYVL  YGTGA+M+VPAHD RD +FA Q +L I  V+
Sbjct  303  TGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL  362

Query  366  VPEGEDPSDKLENAYTEAGTMINSDGFNGMNSVEGKQAIIDYAEKQGWGKARIQYRLRDW  425
                 + ++  E A+TE G  INSD ++G++   +   +++  E +G G+  + YRLRDW
Sbjct  363  -----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDW  417

Query  426  LISRQRYWGAPIPIIHCPSCGAVPVPDEDLPVELPENVEF--TGRGGSPLTQLESWLNVP  483
            L+SRQRYWG PIPIIH     + +VP+ +LP+ LP   ++  +G G SPL+++  WL+V 
Sbjct  418  LFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT  477

Query  484  CPSCGEPAKRETDTMDTFIDSSWYFLRYTDANNSEEVFDQDKVNDWMPVDQYVGGIEHAI  543
                G  ++RET+TM    +SSWY+LRY D++N+E + D++ +++W+PVD YVGG EHA+
Sbjct  478  RED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  544  LHLLYSRFFTKVLRDRGLLNCDEPFQRLLTQGMVQGITYKNPQTGKYIPPQEVNADDPK-  602
            LHLLY+RF  KVL D G++   EPFQ+L+ QGM+ G +Y++++ G  ++ + V+  D   
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSR-GALVATDKVEKRDGSF  595

Query  603  -DPNTGDELSVFFEKMSKSKYNGVDPLEVLDKYGADTARMFILFKAPPEKDLEWDSADVE  661
             + +TG+EL     KMSKS  N V+P +V+++YGADT R++ +F +P +  + W   ++E
Sbjct  596  FHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLE  655

Query  662  GQFRFLNKVWRLVMEFVDRACEVQSKDNNNLSKEEKDLRRAIHTAIKSISEDLEGDYQFN  721
            G  +FL++V RL+      + E+   ++  L K         + ++K+++E+++ + +FN
Sbjct  656  GSRKFLDRVYRLIT-----TKEITEENSGALDK-------VYNETVKAVTEQVD-QMKFN  702

Query  722  TAVSELMKLNNALNEAKCKDSSVYQEGIEALVKLLAPFAPHLTEELWHAL-GNEDSVHHQ  780
            TA+++LM     + +A  K+  ++ +   ++V+L+APFAPHL EELW+AL ++ +S+   
Sbjct  703  TAIAQLM----VFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYV  758

Query  781  TWLEADPDALTVDEINLVIQIKGKTRGTIPVPANASREELETYARESDAAQRYLEGKEVK  840
             W   D   L  +++++V+QIKGK ++ + V+ + SREEL+  A  ++  Q  + GK++ 
Sbjct  759  PWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDII  818

Query  841  KVIVVPGKLVNFVV  854
            KVI VP KLVN+V+
Sbjct  819  KVIAVPNKLVNIVI  832

751) Hore_13370 in NC_011899


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  594 bits (2242),  Expect = 1e-170, Method: Compositional matrix adjust.
 Identities = 388/869 (45%), Positives = 570/869 (66%), Gaps = 76/869 (8%)

Query  2    KGYYNFADIEKKWQDKWEKDGLYKTQEETDKDNYYVLEMFPYPSG-NLHMGHVRVYSIGD  60
              +Y+ + IE KWQ  W  +  +KT  ++ K ++Y L+MFPYPSG  LH+GH   Y+  D
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   VIARFKRMNGYNVLHPMGWDAFGLPAENAAIKHGNIHPQDWTWDNIKNMKKQMKSLGLSY  120
            +++RFKR +G NVLHPMGWDAFGLPAE+ A+  GN +P + T +NI N K+Q+++LG+SY
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGN-DPAEFTAENIANFKRQINALGFSY  119

Query  121  DWDREVTTAKEDYYKWTQWFFVKMFKKGLAYKKKAAVNWCPGCETVLANEQVV-NNACER  179
            DWDREV T+  +YYKWTQW+F K++ KGLAY    +VNW     T +ANE+V+ + + ER
Sbjct  120  DWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSER  179

Query  180  CGTEVEEKELEQWFFKITNYAERLLEDHKLLQNWPEKVKIMQRNWIGRSEGMRIKFPVKG  239
             G  V  K + QW +KIT YAERLLED   + +WPE +K MQRNWIG+S G  + F VK+
Sbjct  180  GGYPVVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKD  238

Query  240  SSEEIEVFTTRPDTIFGATYMVLAPEHPLVEKLISGTEKEKEVRQFIDRVKKQKEMERTS  299
            +  ++ VFTTRPDT+FGATY VLAPEH+LV+  I+ +++   V ++  +   + ++ RT 
Sbjct  239  TDKDFTVFTTRPDTLFGATYAVLAPEHALVDA-ITTSDQAEAVADYKRQASLKSDLARTD  297

Query  300  PESEKEGLFTGAYAINPMTGEEIPIMIANYVLMGYGTGAIMAVPAHDQRDFDFARKYDLP  359
               EK G+ TG+YAINP+ G E+P+ IA+YVL +YGTGAIMAVPAHD+RD +FA++++L 
Sbjct  298  LAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLD  357

Query  360  IRVVIQPEEREEELKDTDLNEAYEGSGHLINSDKYNGLTVKEAFDVMAEDMEKEGIGKRE  419
            I  V++  + EE         A+   G  INSD  +GL    A+  M E +E EG+G+ +
Sbjct  358  IIPVLEGGNVEEA--------AFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNEN  409

Query  420  VNYRLRDWLISRQRYWGTPIPIVY--CEKCGTvpvpeeelpvvlpRDVEFSPTGESPLAK  477
            V YRLRDWL+SRQRYWG PIPI+        +VP +E  L + + +D+  S TGESPLA+
Sbjct  410  VTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLAN  469

Query  478  VDEFVNTTCPVCGGKARRETDTMDTFVDSSWYFLRYTDPKN-DKLPFSKENAKKWFPVDQ  536
            V + ++ T    G K+RRET+TM    +SSWY+LRY DP N +KL+   E  K+W+PVD 
Sbjct  470  VTDWLEVTRE-DGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLA-DEELLKQWLPVDI  527

Query  537  YIGGIEHAILHLLYARFFTKVIYDMDMIDSVEPFTNWLAQGMVL----------------  580
            Y+GG EHA+LHLLYARF  KV+YD++++ + EPF + + QGM+L                
Sbjct  528  YVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDK  587

Query  581  ---KDG---------------AKMSKSKGNVVDPEDILDRFGADTARLFILFAAPPEKDL  622
               +DG               AKMSKS  NVV+P+D+++++GADT R++ +F +P +  +
Sbjct  588  VEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASI  647

Query  623  EWSDRGVEGAERFLNRVWRLVADNIKEIKNTDQASLDVNSFNKNEKDLYRNLHVTIKRVT  682
             WS+ G+EG+ +FL+RV RL++   KEI + + ++LD          +Y +   T+K VT
Sbjct  648  AWSEEGLEGSRKFLDRVYRLIT--TKEITEENSGALD---------KVYNE---TVKAVT  693

Query  683  EDIGERLNFNTAISAIMELTNATYQYLNGVEKVNYTLIKDIIEKMLLILAPFAPHMTEEL  742
            E++ ++++FNTAI+ +M        ++N+ +K +  L+ D     + ++APFAPH+ EEL
Sbjct  694  EQV-DQMKFNTAIAQLM-------VFVNAANKED-KLFSDYAKGFVQLIAPFAPHLGEEL  744

Query  743  WSEL-GNDESIHIQKWPGYEEKALKKDEVTIVVQVNGKVRDKLQVSADIDEDKLKEQVLE  801
            W  L +++ESI    WP+Y+E  L  ++V IVVQ++GKV+ KL V+ D+  + L+E  L 
Sbjct  745  WQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALA  804

Query  802  LPRIQKYTEGKEIVKTIIIPKKLVNIVVK  830
              ++Q    GK+I+K I +P+KLVNIV+K
Sbjct  805  NEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

752) leuS in NC_008319


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  594 bits (2244),  Expect = 9e-171, Method: Compositional matrix adjust.
 Identities = 377/853 (45%), Positives = 573/853 (68%), Gaps = 32/853 (3%)

Query  19   YQPLALEERWQALWKEQRLYETQDPKPGQRAFYALSMFPYPSGT-LHMGHVRNYVITDVI  77
            Y+  A+E +WQA+W +++ + T +  +++  FYAL MFPYPSG+ LH+GH   Y  TD++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKT-GTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDIL  62

Query  78   ARVQRMRGDAVLHPMGWDAFGLPAENAAIERKIEPGVWTDSNIAQMRGQLGRLGLSIDWD  137
            +R +R +G+ VLHPMGWDAFGLPAE+ A++   +P+  T  NIA+ + Q+  LG+S DWD
Sbjct  63   SRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWD  122

Query  138  REVATCHSDYYRWTQWLFLELHAGGLAYQKDATVNWDPVDQTVLANEQVDADGRSWRSGA  197
            REV T +++YY+WTQW+F  L   GLAY+ +  VNW     T +ANE+V +DG S R+G 
Sbjct  123  REVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGY  182

Query  198  LVEKRDLRQWFLRITDYadallddldqlqGWPERVRTMQANWIGRSIGAEIDFQVEAHPG  257
             V ++ +RQW L+IT YA+ LL+DL+++ +WPE ++ MQ NWIG+S GA++ F+V  + +
Sbjct  183  PVVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVK-DTD  240

Query  258  TSITVFTTRPDTLFGVSYLVLAPDHALVDQLTTSEERISVTAFR---DLMAELSQDERTS  314
              +TVFTTRPDTLFG +Y VLAP+HALVD +TTS++  +V+ ++    L ++L++ + + 
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  315  DDQPKRGVPTGAVAINPANGKSIPIWIADYVLADYGTGAVMGVPAHDVRDFSFARQHELP  374
            +   K GV TG+ AINP NGK +P+WIADYVLA YGTGA+M+VPAHD RD  FA+Q +L 
Sbjct  301  E---KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLD  357

Query  375  VQRVIEVSGTNEHVNDGEAWAGPGTLIHSAGFSGLSNDEAKTAITNHGAENGWARAKRQY  434
            +  V+E +  +E      A +  G  I+S  + GL +  A + + +    +G +  +  Y
Sbjct  358  IIPVLEGGNVEE-----AAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTY  412

Query  435  RLRDWLISRQRYWGCPIPIIHCDDCGAVPVPRDQLPVELPTGIDLK--GAGGSPLARAED  492
            RLRDWL+SRQRYWG PIPIIH +D  + +VP  +LP+ LP   D++  G+G SPLA   D
Sbjct  413  RLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTD  472

Query  493  WVSVTCPKCGKPARRETDTMDTFMCSSWYYLRFADPHNRDLPFNATSVNRWLPVKQYVGG  552
            W+ VT     K +RRET+TM     SSWYYLR+ DPHN +   +   +++WLPV  YVGG
Sbjct  473  WLEVTREDGVK-GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGG  531

Query  553  IEHAILHLLYARFFTKALNDRDLLQTKEPFERLLTQGMVQGTTYRNPRTGRYISPAAVKD  612
             EHA+LHLLYARF  K L D +++ TKEPF++L+ QGM+ GT+YR++R +   +    K 
Sbjct  532  AEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKR  591

Query  613  ESNPLDPDDGGPLEVLFEKMSKSKHNGVDPAAVIDRYGADTARMFILFKAPPEKDLEWDD  672
            +++ ++ + G  LE    KMSKS  N V+P  V+++YGADT R++ +F +P +  + W +
Sbjct  592  DGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSE  651

Query  673  ADVEGQFRFLQRLWRLVDSEVNHDGVSPATGESDSDIRRAVHQAIKAVSEDLSDDFQFNT  732
             ++EG  +FL+R+ RL+ +          T E+ + + +  ++++KAV+E++ D+ +FNT
Sbjct  652  EGLEGSRKFLDRVYRLITT-------KEITEENSGALDKVYNETVKAVTEQV-DQMKFNT  703

Query  733  AISELMKLSNSLSSGLAQASPGVRQEAMSALVRLLAPFAPHLAEEFWQRL-GGEDSVHCQ  791
            AI++LM + N+     A+    +  +   ++V+L+APFAPHL+EE+WQ L ++ +S+   
Sbjct  704  AIAQLMVFVNA-----ANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYV  758

Query  792  PWPDHDPEALVLASIEVVIQVKGKVRGSMSVAADCSKEELERLALASDVAQRWLEGKPPR  851
            PWP  D   LV   +E+V+Q+KGKV++ + VA D S+EEL+ +ALA++  Q  + GK   
Sbjct  759  PWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDII  818

Query  852  RVIVVPGKLVNLV  864
            +VI VP KLVN+V
Sbjct  819  KVIAVPNKLVNIV  831

753) leuS in NC_005125


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  593 bits (2238),  Expect = 2e-170, Method: Compositional matrix adjust.
 Identities = 383/849 (46%), Positives = 566/849 (67%), Gaps = 27/849 (3%)

Query  5    YNPHAIEPRRQKQWEEAPHLAMD---GRPKFYALSMFPYPSGA-LHMGHVRNYSITDVIS  60
            Y+  AIEP++Q  W +   +  +   ++PKFYAL MFPYPSGA LH+GH   Y+ TD++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  61   RYKRMRGFNVLHPIGWDAFGLPAENAAIDRGIHPAQWTEQNIAQMREQLKRLGFAYAWER  120
            R+KR +G NVLHP+GWDAFGLPAE+ A+D G +PA+ T +NIA+ + Q++ LGF+Y W+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  121  EVATCSPAYYRWTQKLFLEFWKAGLAYRKAGVVNWDPVDQTVLANEQVDAEGRSWRSGAL  180
            EV T  P YY+WTQ +F  +   GLAY     VNW     T +ANE+V ++G S R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  181  VEKRPLEQWYLKITDYAEELLQALGTLGDWPERVRVMQENWIGKSVGAELCFPINGEPEG  240
            V ++P+ QW LKIT YAE LL+ L  + DWPE ++ MQ NWIGKS GA++ F +++   +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  241  IRVFTTRPDTVYGVTYLVLAPEHPLVERITAPERREAVRAFVAQVQSESEIERVSEDRPK  300
            + VFTTRPDT++G TY VLAPEH+LV+ IT++++ EAV  +  Q    S++ R    + K
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEK  302

Query  301  QGVSTGAVALNPFTGQAVPVWIADYVLFEYGTGAVMGVPGHDERDFVFASQYELPIRLVV  360
             GV TG+ A+NP  G+ +PVWIADYVL  YGTGA+M+VP+HDERD  FA Q++L I  V+
Sbjct  303  TGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL  362

Query  361  QAPDGSLTEPLRAAYTEVGVLVNSGPFNGLDSPTGKLKIVEYAEQQGWGKGRVQYRLRDW  420
            ++  G++ E   AA+TE G+ +NS+ ++GLD +++  K+VE  E +G G+  V YRLRDW
Sbjct  363  EG--GNVEE---AAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDW  417

Query  421  LISRQRYWGCPIPMVYCPECGVVPVPDEQLPVALPGDVEF--SGRGPSPLAKLEGWICVD  478
            L+SRQRYWG PIP++   +    +VP+ +LP+ LP   ++  SG G SPLA++ +W+ V 
Sbjct  418  LFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV-  476

Query  479  CPQCGAPARRETDTMDTFIDSSWYFLRFADARNGAEPFSREAVDYWLPVDQYVGGIEHAI  538
              + G  +RRET+TM    +SSWY+LR+ D++N       E +  WLPVD YVGG EHA+
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  539  LHLLYSRFFTKVLRDRGLLSFDEPFKRLLTQGMVLSNAFVDPATKKYYPPDQVEERGGAF  598
            LHLLY+RF  KVL D G+++  EPF++L+ QGM+L+ ++ D+      + D+VE R+G+F
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRG-ALVATDKVEKRDGSF  595

Query  599  FARPDGTPLVCAMEKMSKSKYNGIDPLTVRSEYGADTARLFVLFKAPPEKELEWSDADVR  658
            F    G  L  A  KMSKS  N ++P  V  +YGADT R++ +F +P +  + WS+ ++ 
Sbjct  596  FHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLE  655

Query  659  GQYSFLGRVWRTVYEFVSGEKPDRPVGEAQERDLRREVHRAIQQVGGDIEQYKFNTAIAA  718
            G   FL+R    VY +++     + + E +   L +  + +++ V  +++Q KFNTAIA 
Sbjct  656  GSRKFLDR----VYRLITT----KEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQ  707

Query  719  LMKLNNAMADYPSGQSPAYKEGVYVIVKLLAPFAPHIGAELWQALGEAGD-IHTSDWPAL  777
            LM + NA    ++ +   + +    +V+L+APFAPH+G ELWQAL  +G+ I    WP+ 
Sbjct  708  LMVFVNA----ANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSY  763

Query  778  DESALVEETIVLVIQVNGKKRDDIQVPAAASEGELQELALASEAVRRHTDGKAIKKVIVV  837
            DES LVE+ + +V+Q++GK +  + V+   S  ELQE+ALA+E V+ +  GK I KVI V
Sbjct  764  DESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAV  823

Query  838  PGRLINLVV  846
            P +L+N+V+
Sbjct  824  PNKLVNIVI  832

754) Cylst_1071 in NC_019757


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  593 bits (2238),  Expect = 2e-170, Method: Compositional matrix adjust.
 Identities = 383/869 (45%), Positives = 570/869 (66%), Gaps = 46/869 (5%)

Query  5    YNPAAIEEKWQKTWVSLGLDKTPTESNKPKFYALSMFPYPSGS-LHMGHVRNYTITDVIA  63
            Y+ +AIE KWQ  W      KT T+++KPKFYAL MFPYPSG+ LH+GH   YT TD+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RLKRMQGYRVLHPMGWDAFGLPAENAAIDRGVPPAKWTYQNIAQMRQQLQRLGLSIDWES  123
            R+KR QG  VLHPMGWDAFGLPAE+ A+D G  PA  T +NIA+ ++Q++ LG+S DW+ 
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EIATCSPDYYKWTQWIFLQFLQAGLAYQKEAAVNWDPIDQTVLANEQVDNEGRSWRSGAK  183
            E+ T  P+YYKWTQWIF ++ + GLAY+ E +VNW     T +ANE+V  +G S R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  184  VERKLLRQWFLKITDYAEELLNDLEKLTGWPERVKLMQANWIGKSTGAYLEFPIIGLDEK  243
            V RK +RQW LKIT YAE LL+DLE + +WPE +K MQ NWIGKSTGA + F + + D  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  244  IGVYTTRPDTVFGVSYLVLAPEHPLTKRVTAKEQQAAVEAFIQEVANQSELERTAEDKPK  303
            + V+TTRPDT+FG +Y VLAPEH+L   +T+ +Q  AV  + ++ + +S+L RT   K K
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEK  302

Query  304  RGIPTGGVAINPFTGEEVPIWIADYVLYEYGTGAVMGVPAHDVRDFKFANNYNLPIEFVI  363
             G+ TG+ AINP  G E+P+WIADYVL  YGTGA+M+VPAHD RD  FA+++NL I  V+
Sbjct  303  TGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL  362

Query  364  vppdavadvdFQQKNLPLIMIDYDNAYTEPGILINSGSFSGMTATDAKQAIVKYAEEQGF  423
               +                   + A+TE G+ INS+ + G+  + A   +V   E +G 
Sbjct  363  EGGNVE-----------------EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGV  405

Query  424  GKLRVQYRLRDWLISRQRYWGAPIPVIHCPNCGIVPVPDKDLPVELP--EDVEFTGRGGS  481
            G+  V YRLRDWL+SRQRYWG PIP+IH  +    +VP+ +LP+ LP   D+  +G G S
Sbjct  406  GNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGES  465

Query  482  PLTQLESWVNVPCPTCGTPAKRETDTMDTFIDSSWYFLRFPDAKNEQQIFDASTTNDWMP  541
            PL+++  W++V     G  ++RET+TM    +SSWY+LR+ D+ N +++ D    ++W+P
Sbjct  466  PLANVTDWLEVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLP  524

Query  542  VDQYVGGIEHAILHLLYSRFFTKVLRDRGLLNFDEPFQRLLTQGMVQGLTYLNPNKGGKD  601
            VD YVGG EHA+LHLLY+RF  KVL D G++   EPFQ+L+ QGM+ G +Y    +++++
Sbjct  525  VDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY----RDSRG  580

Query  602  KWIPSHLVNAADPR--DPQTGEPLQRLYATMSKSKGNGVAPEDVIGKYGIDTARMFILFK  659
              ++++ V+  D    + +TGE L++  A MSKS  N V P+DV+ +YG DT R++ +F 
Sbjct  581  ALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFM  640

Query  660  APPEKDLEWDEADVEGQFRFLNRVWRLVTDYIAAGVSRKQAQLDNLTKPEKDLRRAIHSA  719
            +P +  + W E ++EG  +FL+RV RL+T   +  ++  ++           L +  + +
Sbjct  641  GPLDASIAWSEEGLEGSRKFLDRVYRLIT---TKEITEENSG---------ALDKVYNET  688

Query  720  IQAVTEDVEDDYQFNTAISELMKLSNALTDANCKNSPIYAEGIQTLVVLLAPFAPHIADE  779
            ++AVTE+V D+ +FNTAI++LM     + +A  K+  ++++  + +V L+APFAPH+++E
Sbjct  689  VKAVTEQV-DQMKFNTAIAQLM----VFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEE  743

Query  780  LWQLFGNQG-SVHKQTWPAFDSAALVADEITLVIQIMGKTRGSIQVPSQADKAALEKYAR  838
            LWQ +   G S+    WP++D + LV +++ +V+QI GK ++ + V+ +  +  L+  A 
Sbjct  744  LWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVAL  803

Query  839  ESEIAQRYIEGKEIKKVIVVPGKLVNFVV  867
             +E  Q  I GK+I KVI VP KLVN+V+
Sbjct  804  ANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

755) leuS in NC_007513


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  593 bits (2240),  Expect = 2e-170, Method: Compositional matrix adjust.
 Identities = 370/857 (44%), Positives = 576/857 (68%), Gaps = 34/857 (3%)

Query  32   YDPSALEQRWRARWKDQGLDTTETESSKPGFFALSMFPYPSGS-LHMGHVRNYVITDVIA  90
            YD +A+E +W+A W D+    T T++SKP F+AL MFPYPSG+ LH+GH   Y  TD+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  91   RVQRMRGDSVLHPMGWDAFGLPAENAAIERNIDPGEWTDRNIDQMRNQLDRLGLSIDWDR  150
            R +R +G++VLHPMGWDAFGLPAE+ A++   DP+E T  NI + + Q++ LG+S DWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  151  EQATCHSDYYRWTQWLFLELLEGGLAYRKNATVNWDPVDQTVLANEQVDADGRSWRSGAL  210
            E  T +++YY+WTQW+F  L E GLAY  +  VNW     T +ANE+V +DG S R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  211  VEQRQLNQWFLRITDYAEALLNDLDKLKGWPERVRTMQANWIGRSEGAEITFQVTGSSQQ  270
            V ++ + QW L+IT YAE LL+DL+ + +WPE ++ MQ NWIG+S GA++TF+V ++ ++
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  271  SITVFTTRPDTLSGASYVVLAPEHQLVDGLTTEEHLASVDQFRKQVARLSTIERTSDERP  330
             +TVFTTRPDTL GA+Y VLAPEH LVD++TT ++  +V ++++Q +  S + RT   + 
Sbjct  243  -FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKE  301

Query  331  KQGVATGACVTNPLTGEQLPVWIADYVLADYGTGAVMGVPAHDQRDIQFAKANALPIRQV  390
            K GV TG+   NP+ G ++PVWIADYVLA YGTGA+M+VPAHD+RD +FAK   L I  V
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  391  IDAEGAKEAIDAGKAWTEAGTLINSGVFDGQPSNQGKGSITSHGETAGWATSKVTYRLRD  450
            +++    EA     A TE G  INS+ +DG     + + +    E+ G +  +VTYRLRD
Sbjct  362  LEGGNVEEA-----AFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  451  WLISRQRYWGCPIPVIHCPTCGVVPVPRDDLPVELP--RGIDLSGKGGSPLSQQSDWVNV  508
            WL+SRQRYWG PIP+IH       +VP  +LP+ LP  ++I  SG G SPL++ +DW++V
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  509  SCPCCGGAAKRETDTMDTFMCSSWYFLRFADPHNTDQPFSKEAVRRWLPVKQYVGGIEHA  568
            +    G  ++RET+TM     SSWY+LR+ DPHNT++    E +++WLPV  YVGG EHA
Sbjct  477  TRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  569  ILHLLYSRFFTKALRDRGLIDIDEPFERLLTQGMVQAITYRNPITGKYIATADVSDPNDP  628
            +LHLLY+RF  K L D G++   EPF++L+ QGM+ + +YR++  G  +AT  V   +++
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDS-RGALVATDKVEKRDGS  594

Query  629  -LDPTTGDKLEVLFEKMSKSKYNGVDPAAVIDRYGADTARMFILFKAPPEKDLEWDDADV  687
             ++  TG+ LE    KMSKS  N V+P  V+++YGADT R++ +F +P +  + W + ++
Sbjct  595  FFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGL  654

Query  688  EGQFRFLQRLWRLVENASSTLTDLNSTGCPADLTDQEADVRRALHLAIDAVSDDLNGEIQ  747
            EG  +FL+R+ RL+  ++  +T+           ++ + + +  + ++ AV+++++ +++
Sbjct  655  EGSRKFLDRVYRLI--TTKEITE-----------ENSGALDKVYNETVKAVTEQVD-QMK  700

Query  748  LNTAISELMKLSNTITSSGPDRLRPPILQEALSGLIRLLAPFAPHIAEEFWSRLGGDG-S  806
            +NTAI++LM + N  +++  D+L    + +   G+++L+APFAPH++EE+W  L + G S
Sbjct  701  FNTAIAQLMVFVN--AANKEDKL----FSDYAKGFVQLIAPFAPHLGEELWQALTASGES  754

Query  807  VHQQSWPSVDPSALIQDTISIVIQVKGKVRGSIQAPADADKATLESMALSSDVANKWLEG  866
            +   +WPS D S L+++ + IV+Q+KGKV++ +  + D  +  L+ +AL+++  +  + G
Sbjct  755  ISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAG  814

Query  867  ATPKRVIVVPGKLVNLV  883
                +VI VP KLVN+V
Sbjct  815  KDIIKVIAVPNKLVNIV  831

756) leuS in NC_008261


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  592 bits (2235),  Expect = 4e-170, Method: Compositional matrix adjust.
 Identities = 391/848 (47%), Positives = 575/848 (68%), Gaps = 58/848 (6%)

Query  6    TAIDKKWQEKWAESGLYKFDPNKEGEKLYVLEMFSYPSGSQLHAGHWFNYGPVDSWARFK  65
            TAI+ KWQ  WA++  +K + +    K+Y L+MF+YPSG+ LH GH   Y + D  +RFK
Sbjct  7    TAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSRFK  66

Query  66   RMQGYNVFQPMGFDAFGLPAENFAIKTGIHPQDSTIKNIAKMEEQLKAMGAMFNWENEVV  125
            R QG NV++PMG DAFGLPAE++A+ TG +P + T  NIA+   Q++A+G  ++W+ EV 
Sbjct  67   RAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDREVN  126

Query  126  TCSPEYYKWTQWLFLKLYEKGLAYRKKAPVNWCPSCQTVLANEQVV-DGACERCSTEVTK  184
            T  P+YYKWTQW+F KLYEKGLAY    PVNW     T +ANE+V+ DG+ ER +  V +
Sbjct  127  TTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVR  186

Query  185  KDLTQWFFKITdyadelldklddldWPEKTVSMQKHWIGRSTGSQVNFKVKDSDLNFDVF  244
            K + QW +KIT YA+ LL+ L+++DWPE    MQ++WIG+STG++V FKVKD+D +F VF
Sbjct  187  KPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVF  246

Query  245  TTRVDTLCGVSYVVLAPENPLVDEIVSAEQKEAVENYKEEAKKQSDIERQSISREKTGVF  304
            TTR DTL G +Y VLAPE++LVD I +++Q EAV +YK +A  +SD+ R  +++EKTGV 
Sbjct  247  TTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVW  306

Query  305  TGAYAIHPLTGKEVPIWVGDYVLATYGTGAVMAVPAHDERDFAFAEKFNLPINRVIEAKD  364
            TG+YAI+P+ GKE+P+W++DYVLA+YGTGA+MAVPAHDERD  FA +FNL I  V+E+ +
Sbjct  307  TGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGN  366

Query  365  GSETNLPFCEHGILVNSGEFDGLTTDEAKEKIVEKLASMGLGEKKVNFRLRDWLVSRQRY  424
              E+  +F E+G+ +NS+ +DGL    A  K+VE L + G+G+ +V +RLRDWL SRQRY
Sbjct  367  VEEA--AFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRY  424

Query  425  WGAPIPVVYCEECGIVPVPESQLPVELPYDVEFAPDGK--SPLAKSEAFVNTTCPHCGKP  482
            WG PIP++  E+    +VPES+LP+ LP   ++ P G   SPLA+    ++ T  +  K 
Sbjct  425  WGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK-  483

Query  483  AKRETDTLDTFVCSSWYYLRYPDNKNTEAPFNPELINKMLPVDKYVGGPEHACMHLLYAR  542
            ++RET+T+     SSWYYLRY D  NTE   + EL+++ LPVD YVGG+EHA +HLLYAR
Sbjct  484  GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYAR  543

Query  543  FITKALRDMGYLNFDEPFTSLTHQGLILGP----------------------------DG  574
            F  K L D+G +   EPF  L +QG+ILG                             + 
Sbjct  544  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEE  603

Query  575  L-----KMSKSKGNTISPDDYIKEYGADVFRMYLMFGFAYTEGGAWSDDGIKSVNRFVER  629
            L     KMSKS  N ++PDD + +YGAD +R+Y MF  +   + AWS++G+ +  +F++R
Sbjct  604  LEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR  663

Query  630  IERIIDTAREAISKGENNKTTMDKAEKELNYWRHNTIKSVTDDTDKLQFNTAIARMMEFI  689
            + R+I T++E     E+N  ++DK      Y  ++T+K+VT++ D+++FNTAIA++M F+
Sbjct  664  VYRLI-TTKEI---TEENSGALDKV-----Y--NETVKAVTEQVDQMKFNTAIAQLMVFV  712

Query  690  NALSKYTQEKEMNLDFLKDVVSDYLRLLAPFAPHFSEEQW-SLLGNSYSIFNEAWPKFDP  748
            NA +K  ++K     ++ D   ++++L+APFAPH++EE W +L +++ SI   +WP +D 
Sbjct  713  NAANK--EDK-----LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDE  765

Query  749  KALVKDEVEIAIQVNGKIKNKIMVSSDLDEEGIKAAALADEKIIASTEGKTvvkvivikG  808
              LV ++VEI +Q++GK+K K++V+ DL  E ++  ALA+EK+ A   GK ++KVI +  
Sbjct  766  SKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPN  825

Query  809  RLVNIVVK  816
            +LVNIV+K
Sbjct  826  KLVNIVIK  833

757) leuS in NC_008593


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  592 bits (2235),  Expect = 4e-170, Method: Compositional matrix adjust.
 Identities = 380/846 (45%), Positives = 555/846 (66%), Gaps = 58/846 (6%)

Query  6    TTVDEKWQKKWEESGLHNFDENAPGEKLYVLEMFSYPSAAKLHAGHWFNYGPTDSWARFK  65
            T+++ KWQ  W ++   + + +A+  K+Y L+MF+YPS+A LH GH   Y +TD  +RFK
Sbjct  7    TAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSRFK  66

Query  66   KMNGYNVFQPMGFDAFGLPAENFAIKTGIHPQDSTMKNIENMEEQLRSMGAMFNWDHEII  125
            + +G NV++PMG DAFGLPAE++A+ TG +P + T  NI N   Q+ ++G  ++WD+E+ 
Sbjct  67   RAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDREVN  126

Query  126  TCLPDYYKWTQWVFLKLYEKGLAYRKNAPVNWCPSCNTVLANEQVL-DGHCERCDSLVEK  184
            T  P+YYKWTQW+F KLYEKGLAY  + PVNW     T +ANE+VL DG  ER +  V +
Sbjct  127  TTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVR  186

Query  185  KALTQWFLKITDYADELLEKLDGLDWPEKTKAMQKHWIGKSKGVEATFKVENSDITFDVF  244
            K++ QW LKIT YA+ LLE L+ +DWPE  K MQ++WIGKS G + TFKV ++D  F VF
Sbjct  187  KPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVF  246

Query  245  TTRVDTLNGVTYVVLAPENELVDSLTTEENKAAVEAYKIEAQKQSDIERQSSTREKTGVF  304
            TTR DTL G TY VLAPE+ LVD++TT ++  AV  YK +A  +SD+ R   ++EKTGV 
Sbjct  247  TTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVW  306

Query  305  TGSYAINPINGNKVPIWVGDYVLATYGTGCVMAVPAHDERDYAFATKYDLPIVRVIEGG-  363
            TGSYAINP+NG+ +P+W++DYVLA+YGTG +MAVPAHDERD  FA +++L I+ V+EGG 
Sbjct  307  TGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGN  366

Query  364  -DSLPFTEYGSLVNSGEFDGLYGEEAKEAIVKKLQEQKLGNWKVNYRLRDWLVSRQRYWG  422
             +  +FTE G  +NS+ +DGL    A   +V  L+ + +GN +V YRLRDWL SRQRYWG
Sbjct  367  VEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWG  426

Query  423  APIPVVYCDKCGTVAVPEEQLPVELPYNIEFTPDGK--SPLSKSEEFLHTTCPKCGGHAV  480
             PIP++  +   + AVPE +LP+ LP   ++ P G   SPL++  + L+ T    G  + 
Sbjct  427  EPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED-GVKGR  485

Query  481  RETDTLDTFVCSSWYYLRYVDNNNSEKAFDIDKVNKMLPVDKYVGGPEHACMHLLYARFI  540
            RET+T+     SSWYYLRY+D +N+EK  D + +++ LPVD YVGG+EHA +HLLYARF 
Sbjct  486  RETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFW  545

Query  541  TKALRDMGYLNFDEPFTSLTHQGLILGP----------------------------DGL-  571
             K L D+G +   EPF  L +QG+ILG                             + L 
Sbjct  546  HKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEELE  605

Query  572  ----KMSKSKGNTIAPDDYIKEYGADVFRMYLMFGFAYSEGGAWSDDAIKSMSKFVDKVE  627
                KMSKS  N + PDD + +YGAD +R+Y MF  +   + AWS++++ +  KF+D+V 
Sbjct  606  QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVY  665

Query  628  RILADSRTQMADSKNTKTTIEKAEKELNYTRHYAIQHVTEDTEKFQFNTAIARIMEYTNS  687
            R+++           TK   E     L+   + +++ VTE+ ++ +FNTAIA++M + N+
Sbjct  666  RLIT-----------TKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNA  714

Query  688  LSKYLNEENLNVEFLKEALTDYIKLLAPFAPHFSEEQWELLGNTSSVFT-TSWPKFDPKA  746
             +K   E++L  ++ K    ++++L+APFAPH++EE W+ L  ++  ++  +WP +D   
Sbjct  715  ANK---EDKLFSDYAK----GFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESK  767

Query  747  LVKDEVEIAIQILGKIKARMNIATNLTDEEIKEAALNNETIKGLLEGKNIIKVIVVKGSL  806
            LV ++VEI +QI GK+KA++ +A +L+ EE++E AL NE +++ + GK+IIKVI V   L
Sbjct  768  LVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKL  827

Query  807  VNIVAK  812
            VNIV K
Sbjct  828  VNIVIK  833

758) Cyan10605_2867 in NC_019776


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  592 bits (2235),  Expect = 4e-170, Method: Compositional matrix adjust.
 Identities = 372/844 (45%), Positives = 562/844 (67%), Gaps = 32/844 (3%)

Query  5    YQPSDIESKWQQQWSDSNLYLTEENRDKPKFYALSMFPYPSGK-LHMGHVRNYVITDVIA  63
            Y+ + IE+KWQ  W+D++ + T  +  KPKFYAL MFPYPSG  LH+GH   Y  TD+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RFKRMQGHRVLHPMGWDAFGLPAENAAIDRGIPPAKWTYENIAQMRSQLQELGLSIDWSR  123
            RFKR QGH VLHPMGWDAFGLPAE+ A+D G  PA  T ENIA+ + Q++ LG+S DW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVATCSPDYYKWTQWLFLQFYEAGLAYQKEAAVNWDPIDQTVLANEQVDSEGYSWRSGAK  183
            EV T  P+YYKWTQW+F ++YE GLAY+ E +VNW     T +ANE+V ++G S R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  184  VERKLLRQWFLKITDYAEQLLNDLQQLEGWPDRVKTMQENWIGKSVGAYLEFPIVGSDEK  243
            V RK +RQW LKIT YAE+LL+DL++++ WP+ +K MQ NWIGKS GA + F + ++D  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  244  IPVFTTRPDTVYGVTYVVLAPEHPLTEKVTTPERKEAVSAFIQEVSSESEIDRTADDKPK  303
            + VFTTRPDT++G TY VLAPEH+L + +TT+++ EAV+ + ++ S  S++ RT   K K
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEK  302

Query  304  KGILTGGKAINPFTGEEIPILIANYVLYEYGTGAVMGVPAHDVRDFKFAKENNLPIKVVI  363
             G+ TG+ AINP  G E+P+ IA+YVL  YGTGA+M+VPAHD RD  FAK+ NL I  V+
Sbjct  303  TGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL  362

Query  364  LPENVEETDFSLVEAYTETGIMVNSGEFNGMESTQGKEAVIKLAENKGFGKKRIQYRLRD  423
               NVEE+ F      TE G+ +NS+ ++G++ + +   ++   E  G G+  + YRLRD
Sbjct  363  EGGNVEEAAF------TEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  424  WLISRQRYWGCPIPVIHCQDCGTVPVPTEQLPVELPEQVEF--SGRGPSPLAKLDDWVNV  481
            WL+SRQRYWG PIP+IH +D  + +VP  +LP+ LP   ++  SG G SPLA++ DW++V
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  482  TCPKCGKPAKRETDTMDTFIDSSWYFLRYTDATNQNEPFNLDRVNDWMGVDQYVGGIEHA  541
            T     K ++RET+TM    +SSWY+LRY D+ N +   + + +++W+ VD YVGG EHA
Sbjct  477  TREDGVK-GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  542  ILHLLYSRFFTKVVRDRGLVCVDEPFKRLLTQGMVQGLTYKTKQTGKYLTPEQIIYKNGE  601
            +LHLLY+RF  KV+ D G+V   EPF++L+ QGM+ G +Y+  + G  ++ +++  ++G 
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSR-GALVATDKVEKRDGS  594

Query  602  CRDKETNEPVNIFYEKMSKSKYNGVDPKLVLEKYGADTARMFILFKAPPEKDLEWDDADV  661
              + ET E ++    KMSKS  N V+P  V+E+YGADT R++ +F +P +  + W + ++
Sbjct  595  FFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGL  654

Query  662  EGQYRFLNRVWLLVNEFIENPDSAEDKTINKANLSKEEKDLRRAIHTAIKEISEDLSGDY  721
            EG  +FL+RV  L+                K     +   L +  + ++K ++E++ ++ 
Sbjct  655  EGSRKFLDRVYRLIT--------------TKEITEENSGALDKVYNETVKAVTEQV-DQM  699

Query  722  QFNTAVSELMKLSNALRDAKIKNSPVYREGVETLILLLAPFAPHISEELWHKL-GNSESV  780
            +FNTA+++LM + NA      K+  ++ +    ++ L+APFAPH++EELW+ L +++ES+
Sbjct  700  KFNTAIAQLMVFVNAAN----KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESI  755

Query  781  HLANWLIIDEEALTVDEITLVIQIKGKTRGTISAPASASKDELEAIARASDIAQKYIADK  840
                W   DE  L  +++ +V+QIKGK ++ +  +   S++EL+ +A A++  Q  IA+K
Sbjct  756  SYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGK  815

Query  841  EIKK  844
            +I K
Sbjct  816  DIIK  819

759) leuS in NC_010628


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  592 bits (2235),  Expect = 4e-170, Method: Compositional matrix adjust.
 Identities = 379/872 (44%), Positives = 580/872 (67%), Gaps = 49/872 (5%)

Query  5    YNPAAIEEKRQKTWLELGLDKTPSASNKPKFYALSMFPYPSG-SLHMGHVRNYTITDVIA  63
            Y+ +AIE K+Q  W +    KT + ++KPKFYAL MFPYPSG +LH+GH   YT TD+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RFKRMQGYRVIHPMGWDAFGLPAENAAIDRGVPPAKWTYQNITQMRQQLQRLGLSIDWEC  123
            RFKR QG  V+HPMGWDAFGLPAE+ A+D G  PA  T +NI++ ++Q++ LG+S DW+ 
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCSPDYYKWTQWIFLQFLQAGLAYQKEAAVNWDPIDQTVLANEQVDNEGRSWRSGAI  183
            E+ T  P+YYKWTQWIF ++ + GLAY+ E +VNW     T +ANE+V  +G S R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  184  VERKLLRQWFFKITDYAEELLNDLDKLTGWPERVKLMQANWIGKSTGAYLEFPIVGIDEK  243
            V RK +RQW +KIT YAE LL+DL+ + +WPE +K MQ NWIGKSTGA + F + + D  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  244  IAVYTTRPDTVYGVSYLVLAPEHPLTNRVTTKEQQAAVEVFIKEVSNQSELERTSEDKPK  303
            ++V+TTRPDT++G +Y VLAPEH+L + +TT +Q  AV  + ++ S +S+L RT   K K
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEK  302

Query  304  RGIPTGGVAINPFTGEEVPIWIADYVLYEYGTGAVMGVPAHDVRDFKFAKNYDLPINFVI  363
             G+ TG+ AINP  G E+P+WIADYVL  YGTGA+M+VPAHD RD  FAK+++L      
Sbjct  303  TGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNL------  356

Query  364  ASPDDVAGFDLTPTSEIDGITQLVEVDYKQAYTEPGILINSGAFTGISSTDAKQAIIEYA  423
                     D+ P  E + + +        A+TE G+ INS+ + G+  + A   ++E  
Sbjct  357  ---------DIIPVLEGGNVEE-------AAFTEDGLHINSDFLDGLDKASAIAKMVEWL  400

Query  424  EKQDFGKVRVQYRLRDWLISRQRYWGAPIPVIHCPNCGIVPVPDKDLPVQLP--EEVEFT  481
            E ++ G+  V YRLRDWL+SRQRYWG PIP+IH  +    +VP+ +LP+ LP   ++  +
Sbjct  401  EAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPS  460

Query  482  GRCGSPLTQLESWVNVPCPTCGTPAKRETDTMDTFIDSSWYFLRFPDAKNEQQVFDSSKV  541
            G   SPL+++  W++V     G  ++RET+TM    +SSWY+LR+ D+ N +++ D   +
Sbjct  461  GTGESPLANVTDWLEVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELL  519

Query  542  NDWMPVNQYVGGIEHAILHLLYSRFFTKVLRDRGLLNFDEPFQRLLTQGMVQGLTYLNPN  601
            ++W+PV+ YVGG EHA+LHLLY+RF  KVL D G++   EPFQ+L+ QGM+ G +Y    
Sbjct  520  KQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY----  575

Query  602  KGGKDKWIPSNLVNSADPR--DPQTDEPLQRLYATMSKSKGNGVAPEDVISKYGIDTARM  659
            +++++  ++++ V+  D    + +T+E L++  A MSKS  N V P+DV+ +YG DT R+
Sbjct  576  RDSRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRV  635

Query  660  FILFKAPPEKDLEWDEADVEGQFRFLNRVWRLVTDYITAGVSRKKAQSDLTKAEKELRRA  719
            + +F +P +  + W E ++EG  +FL+RV RL+T   T  ++  ++ +        L + 
Sbjct  636  YEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLIT---TKEITEENSGA--------LDKV  684

Query  720  IHTAIQAVTEDVEDEYQFNTAISELMKLSNALSDADKNSPIYAEGIRTLVILIAPFAPHI  779
             + +++AVTE+V D+ +FNTAI++LM + NA   A+K+  ++++  + +V LIAPFAPH+
Sbjct  685  YNETVKAVTEQV-DQMKFNTAIAQLMVFVNA---ANKEDKLFSDYAKGFVQLIAPFAPHL  740

Query  780  ADELWH-LLGESDSIHTQTWPSFDPAALVADEITLVIQVMGKTRGAIQVPAQADKAALEK  838
            ++ELW+ L + ++SI    WPS+D + LV +++ +V+Q+ GK ++ + V+ +  +  L+ 
Sbjct  741  GEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQE  800

Query  839  YARESEIAQRYIEGKEIKKVIVVPGKLVNFVV  870
             A  +E  Q  I GK+I KVI VP KLVN+V+
Sbjct  801  VALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

760) leuS in NC_017038


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  591 bits (2234),  Expect = 5e-170, Method: Compositional matrix adjust.
 Identities = 386/870 (45%), Positives = 567/870 (66%), Gaps = 47/870 (5%)

Query  5    YNAGEIEQKWQQRWAEWGLDKTPIASDLPKFYALSMFPYPSG-NLHMGHVRNYTITDVIA  63
            Y+   IE KWQ  WA+    KT   +  PKFYAL MFPYPSG  LH+GH   YT TD+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RLKRMQGYQVLHPMGWDAFGLPAENAAIERGIPPKQWTEKNIAQMRAQLQQLGLSIDWER  123
            R+KR QG +VLHPMGWDAFGLPAE+ A++ G  P + T  NIA+ + Q++ LG+S DW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVATCAPDYYRWTQWLFLEFFQAGLAYQKEATVNWDPIDQTVLANEQVDSEGRSWRSGAM  183
            EV T  P+YY+WTQW+F  +++ GLAY+ E  VNW     T +ANE+V ++G S R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  184  VERKLLRQWFLKITDYAEALLNDLEQLTGWPERVKLMQSHWIGKSVGAYLEFPIKDSQEK  243
            V RK +RQW LKIT YAE LL+DLE++ +WPE +K MQ +WIGKS GA + F +KD++  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  244  IAVFTTRPDTVYGVTYVVLAPEHPLTKVVTTAEQQGTVDEFVAMVAKESEIERTAEDKPK  303
            ++VFTTRPDT++G TY VLAPEH+L   +TT++Q  +V ++    +  S++ RT   K K
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEK  302

Query  304  RGVKTGGIAINPFNGEEIPILIADYVLYEYGTGAVMGVPAHDQRDFKFAQDNNLPMQVVI  363
             GV TG+ AINP NG E+P+ IADYVL  YGTGA+M+VPAHD+RD  FA++ NL +  V+
Sbjct  303  TGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL  362

Query  364  IPDDADNSDVNLTVAYTEAGVMVNSAQFTGMASPKAKQAIIKFAEDNDYGRAKVQYRLRD  423
              ++ +++      A+TE G+ +NS  + G+  + A   ++   E ++ G  +V YRLRD
Sbjct  363  EGGNVEEA------AFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  424  WLISRQRYWGCPIPIIHCDDCGAVPVPTKDLPVELPDNVEF--SGRGPSPLAKLEDWINV  481
            WL+SRQRYWG PIPIIH +D  + +VP  +LP+ LP   ++  SG G SPLA++ DW++V
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  482  PCPSCGKPARRETDTMDTFIDSSWYFLRYADAQNTELPFDGEKVAHWLPVDQYVGGIEHA  541
                  K +RRET+TM    +SSWY+LRY D++NTE   D E + +WLPVD YVGG EHA
Sbjct  477  TREDGVK-GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  542  ILHLLYSRFFTKVLADRQLIPVKEPFQKLLTQGMVQGITYKNPTTGKYVPAKDLQTGQQV  601
            +LHLLY+RF  KVL D  ++P KEPFQKL+ QGM+ G +Y++        +++   + + 
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRD--------SRGALVATDK  587

Query  602  IDPKDPK--DPDSGEPLQVFYEKMSKSKFNGVDPQEVLAKYGADTARMFILFKAPPEKDL  659
            ++ +D    + ++GE L+    KMSKS  N V+P++V+ +YGADT R++ +F +P +  +
Sbjct  588  VEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASI  647

Query  660  EWDDADVEGQFRFLNRVWRLVTDYIGDPAGIRFAVRPETLVTNEPLTKAEKDLRRAIHGA  719
             W + ++EG  +FL+RV RL+T                   T+E        L +  + +
Sbjct  648  AWSEEGLEGSRKFLDRVYRLIT-------------------TKEITEENSGALDKVYNET  688

Query  720  IKEVAEDLNDDYQFNTAISEMMKLSNALIAATDLISFPVYQEGIETlllllAPFAPHLTE  779
            +K V+E++ D+ +FNTAI+++M + NA      L  F+ Y  G+   + L+APFAPHL E
Sbjct  689  VKAVTEQV-DQMKFNTAIAQLMVFVNAANKEDKL--FSDYAKGF---VQLIAPFAPHLGE  742

Query  780  ELWHRL-GRTDSIHQQAWLQVDPTALVLDEITLVIQVLGKTRGTITVPASADKTQLEELA  838
            ELW+ L +  +SI   +W   D + LV +++ +V+Q+ GK ++ + V+    + +L+E+A
Sbjct  743  ELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVA  802

Query  839  RNSDLAQRYLEGKTIKKVIVVPGKLVNFVI  868
              ++  Q  + GK I KVI VP KLVN+VI
Sbjct  803  LANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

761) leuS in NC_017052


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  591 bits (2234),  Expect = 5e-170, Method: Compositional matrix adjust.
 Identities = 386/870 (45%), Positives = 567/870 (66%), Gaps = 47/870 (5%)

Query  5    YNAGEIEQKWQQRWAEWGLDKTPIASDLPKFYALSMFPYPSG-NLHMGHVRNYTITDVIA  63
            Y+   IE KWQ  WA+    KT   +  PKFYAL MFPYPSG  LH+GH   YT TD+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RLKRMQGYQVLHPMGWDAFGLPAENAAIERGIPPKQWTEKNIAQMRAQLQQLGLSIDWER  123
            R+KR QG +VLHPMGWDAFGLPAE+ A++ G  P + T  NIA+ + Q++ LG+S DW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVATCAPDYYRWTQWLFLEFFQAGLAYQKEATVNWDPIDQTVLANEQVDSEGRSWRSGAM  183
            EV T  P+YY+WTQW+F  +++ GLAY+ E  VNW     T +ANE+V ++G S R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  184  VERKLLRQWFLKITDYAEALLNDLEQLTGWPERVKLMQSHWIGKSVGAYLEFPIKDSQEK  243
            V RK +RQW LKIT YAE LL+DLE++ +WPE +K MQ +WIGKS GA + F +KD++  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  244  IAVFTTRPDTVYGVTYVVLAPEHPLTKVVTTAEQQGTVDEFVAMVAKESEIERTAEDKPK  303
            ++VFTTRPDT++G TY VLAPEH+L   +TT++Q  +V ++    +  S++ RT   K K
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEK  302

Query  304  RGVKTGGIAINPFNGEEIPILIADYVLYEYGTGAVMGVPAHDQRDFKFAQDNNLPMQVVI  363
             GV TG+ AINP NG E+P+ IADYVL  YGTGA+M+VPAHD+RD  FA++ NL +  V+
Sbjct  303  TGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL  362

Query  364  IPDDADNSDVNLTVAYTEAGVMVNSAQFTGMASPKAKQAIIKFAEDNDYGRAKVQYRLRD  423
              ++ +++      A+TE G+ +NS  + G+  + A   ++   E ++ G  +V YRLRD
Sbjct  363  EGGNVEEA------AFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  424  WLISRQRYWGCPIPIIHCDDCGAVPVPTKDLPVELPDNVEF--SGRGPSPLAKLEDWINV  481
            WL+SRQRYWG PIPIIH +D  + +VP  +LP+ LP   ++  SG G SPLA++ DW++V
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  482  PCPSCGKPARRETDTMDTFIDSSWYFLRYADAQNTELPFDGEKVAHWLPVDQYVGGIEHA  541
                  K +RRET+TM    +SSWY+LRY D++NTE   D E + +WLPVD YVGG EHA
Sbjct  477  TREDGVK-GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  542  ILHLLYSRFFTKVLADRQLIPVKEPFQKLLTQGMVQGITYKNPTTGKYVPAKDLQTGQQV  601
            +LHLLY+RF  KVL D  ++P KEPFQKL+ QGM+ G +Y++        +++   + + 
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRD--------SRGALVATDK  587

Query  602  IDPKDPK--DPDSGEPLQVFYEKMSKSKFNGVDPQEVLAKYGADTARMFILFKAPPEKDL  659
            ++ +D    + ++GE L+    KMSKS  N V+P++V+ +YGADT R++ +F +P +  +
Sbjct  588  VEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASI  647

Query  660  EWDDADVEGQFRFLNRVWRLVTDYIGDPAGIRFAVRPETLVTNEPLTKAEKDLRRAIHGA  719
             W + ++EG  +FL+RV RL+T                   T+E        L +  + +
Sbjct  648  AWSEEGLEGSRKFLDRVYRLIT-------------------TKEITEENSGALDKVYNET  688

Query  720  IKEVAEDLNDDYQFNTAISEMMKLSNALIAATDLISFPVYQEGIETlllllAPFAPHLTE  779
            +K V+E++ D+ +FNTAI+++M + NA      L  F+ Y  G+   + L+APFAPHL E
Sbjct  689  VKAVTEQV-DQMKFNTAIAQLMVFVNAANKEDKL--FSDYAKGF---VQLIAPFAPHLGE  742

Query  780  ELWHRL-GRTDSIHQQAWLQVDPTALVLDEITLVIQVLGKTRGTITVPASADKTQLEELA  838
            ELW+ L +  +SI   +W   D + LV +++ +V+Q+ GK ++ + V+    + +L+E+A
Sbjct  743  ELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVA  802

Query  839  RNSDLAQRYLEGKTIKKVIVVPGKLVNFVI  868
              ++  Q  + GK I KVI VP KLVN+VI
Sbjct  803  LANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

762) leuS in NC_017039


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  591 bits (2234),  Expect = 5e-170, Method: Compositional matrix adjust.
 Identities = 386/870 (45%), Positives = 567/870 (66%), Gaps = 47/870 (5%)

Query  5    YNAGEIEQKWQQRWAEWGLDKTPIASDLPKFYALSMFPYPSG-NLHMGHVRNYTITDVIA  63
            Y+   IE KWQ  WA+    KT   +  PKFYAL MFPYPSG  LH+GH   YT TD+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RLKRMQGYQVLHPMGWDAFGLPAENAAIERGIPPKQWTEKNIAQMRAQLQQLGLSIDWER  123
            R+KR QG +VLHPMGWDAFGLPAE+ A++ G  P + T  NIA+ + Q++ LG+S DW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVATCAPDYYRWTQWLFLEFFQAGLAYQKEATVNWDPIDQTVLANEQVDSEGRSWRSGAM  183
            EV T  P+YY+WTQW+F  +++ GLAY+ E  VNW     T +ANE+V ++G S R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  184  VERKLLRQWFLKITDYAEALLNDLEQLTGWPERVKLMQSHWIGKSVGAYLEFPIKDSQEK  243
            V RK +RQW LKIT YAE LL+DLE++ +WPE +K MQ +WIGKS GA + F +KD++  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  244  IAVFTTRPDTVYGVTYVVLAPEHPLTKVVTTAEQQGTVDEFVAMVAKESEIERTAEDKPK  303
            ++VFTTRPDT++G TY VLAPEH+L   +TT++Q  +V ++    +  S++ RT   K K
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEK  302

Query  304  RGVKTGGIAINPFNGEEIPILIADYVLYEYGTGAVMGVPAHDQRDFKFAQDNNLPMQVVI  363
             GV TG+ AINP NG E+P+ IADYVL  YGTGA+M+VPAHD+RD  FA++ NL +  V+
Sbjct  303  TGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL  362

Query  364  IPDDADNSDVNLTVAYTEAGVMVNSAQFTGMASPKAKQAIIKFAEDNDYGRAKVQYRLRD  423
              ++ +++      A+TE G+ +NS  + G+  + A   ++   E ++ G  +V YRLRD
Sbjct  363  EGGNVEEA------AFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  424  WLISRQRYWGCPIPIIHCDDCGAVPVPTKDLPVELPDNVEF--SGRGPSPLAKLEDWINV  481
            WL+SRQRYWG PIPIIH +D  + +VP  +LP+ LP   ++  SG G SPLA++ DW++V
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  482  PCPSCGKPARRETDTMDTFIDSSWYFLRYADAQNTELPFDGEKVAHWLPVDQYVGGIEHA  541
                  K +RRET+TM    +SSWY+LRY D++NTE   D E + +WLPVD YVGG EHA
Sbjct  477  TREDGVK-GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  542  ILHLLYSRFFTKVLADRQLIPVKEPFQKLLTQGMVQGITYKNPTTGKYVPAKDLQTGQQV  601
            +LHLLY+RF  KVL D  ++P KEPFQKL+ QGM+ G +Y++        +++   + + 
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRD--------SRGALVATDK  587

Query  602  IDPKDPK--DPDSGEPLQVFYEKMSKSKFNGVDPQEVLAKYGADTARMFILFKAPPEKDL  659
            ++ +D    + ++GE L+    KMSKS  N V+P++V+ +YGADT R++ +F +P +  +
Sbjct  588  VEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASI  647

Query  660  EWDDADVEGQFRFLNRVWRLVTDYIGDPAGIRFAVRPETLVTNEPLTKAEKDLRRAIHGA  719
             W + ++EG  +FL+RV RL+T                   T+E        L +  + +
Sbjct  648  AWSEEGLEGSRKFLDRVYRLIT-------------------TKEITEENSGALDKVYNET  688

Query  720  IKEVAEDLNDDYQFNTAISEMMKLSNALIAATDLISFPVYQEGIETlllllAPFAPHLTE  779
            +K V+E++ D+ +FNTAI+++M + NA      L  F+ Y  G+   + L+APFAPHL E
Sbjct  689  VKAVTEQV-DQMKFNTAIAQLMVFVNAANKEDKL--FSDYAKGF---VQLIAPFAPHLGE  742

Query  780  ELWHRL-GRTDSIHQQAWLQVDPTALVLDEITLVIQVLGKTRGTITVPASADKTQLEELA  838
            ELW+ L +  +SI   +W   D + LV +++ +V+Q+ GK ++ + V+    + +L+E+A
Sbjct  743  ELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVA  802

Query  839  RNSDLAQRYLEGKTIKKVIVVPGKLVNFVI  868
              ++  Q  + GK I KVI VP KLVN+VI
Sbjct  803  LANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

763) leuS in NC_017277


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  591 bits (2234),  Expect = 5e-170, Method: Compositional matrix adjust.
 Identities = 386/870 (45%), Positives = 567/870 (66%), Gaps = 47/870 (5%)

Query  5    YNAGEIEQKWQQRWAEWGLDKTPIASDLPKFYALSMFPYPSG-NLHMGHVRNYTITDVIA  63
            Y+   IE KWQ  WA+    KT   +  PKFYAL MFPYPSG  LH+GH   YT TD+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RLKRMQGYQVLHPMGWDAFGLPAENAAIERGIPPKQWTEKNIAQMRAQLQQLGLSIDWER  123
            R+KR QG +VLHPMGWDAFGLPAE+ A++ G  P + T  NIA+ + Q++ LG+S DW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVATCAPDYYRWTQWLFLEFFQAGLAYQKEATVNWDPIDQTVLANEQVDSEGRSWRSGAM  183
            EV T  P+YY+WTQW+F  +++ GLAY+ E  VNW     T +ANE+V ++G S R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  184  VERKLLRQWFLKITDYAEALLNDLEQLTGWPERVKLMQSHWIGKSVGAYLEFPIKDSQEK  243
            V RK +RQW LKIT YAE LL+DLE++ +WPE +K MQ +WIGKS GA + F +KD++  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  244  IAVFTTRPDTVYGVTYVVLAPEHPLTKVVTTAEQQGTVDEFVAMVAKESEIERTAEDKPK  303
            ++VFTTRPDT++G TY VLAPEH+L   +TT++Q  +V ++    +  S++ RT   K K
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEK  302

Query  304  RGVKTGGIAINPFNGEEIPILIADYVLYEYGTGAVMGVPAHDQRDFKFAQDNNLPMQVVI  363
             GV TG+ AINP NG E+P+ IADYVL  YGTGA+M+VPAHD+RD  FA++ NL +  V+
Sbjct  303  TGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL  362

Query  364  IPDDADNSDVNLTVAYTEAGVMVNSAQFTGMASPKAKQAIIKFAEDNDYGRAKVQYRLRD  423
              ++ +++      A+TE G+ +NS  + G+  + A   ++   E ++ G  +V YRLRD
Sbjct  363  EGGNVEEA------AFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  424  WLISRQRYWGCPIPIIHCDDCGAVPVPTKDLPVELPDNVEF--SGRGPSPLAKLEDWINV  481
            WL+SRQRYWG PIPIIH +D  + +VP  +LP+ LP   ++  SG G SPLA++ DW++V
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  482  PCPSCGKPARRETDTMDTFIDSSWYFLRYADAQNTELPFDGEKVAHWLPVDQYVGGIEHA  541
                  K +RRET+TM    +SSWY+LRY D++NTE   D E + +WLPVD YVGG EHA
Sbjct  477  TREDGVK-GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  542  ILHLLYSRFFTKVLADRQLIPVKEPFQKLLTQGMVQGITYKNPTTGKYVPAKDLQTGQQV  601
            +LHLLY+RF  KVL D  ++P KEPFQKL+ QGM+ G +Y++        +++   + + 
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRD--------SRGALVATDK  587

Query  602  IDPKDPK--DPDSGEPLQVFYEKMSKSKFNGVDPQEVLAKYGADTARMFILFKAPPEKDL  659
            ++ +D    + ++GE L+    KMSKS  N V+P++V+ +YGADT R++ +F +P +  +
Sbjct  588  VEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASI  647

Query  660  EWDDADVEGQFRFLNRVWRLVTDYIGDPAGIRFAVRPETLVTNEPLTKAEKDLRRAIHGA  719
             W + ++EG  +FL+RV RL+T                   T+E        L +  + +
Sbjct  648  AWSEEGLEGSRKFLDRVYRLIT-------------------TKEITEENSGALDKVYNET  688

Query  720  IKEVAEDLNDDYQFNTAISEMMKLSNALIAATDLISFPVYQEGIETlllllAPFAPHLTE  779
            +K V+E++ D+ +FNTAI+++M + NA      L  F+ Y  G+   + L+APFAPHL E
Sbjct  689  VKAVTEQV-DQMKFNTAIAQLMVFVNAANKEDKL--FSDYAKGF---VQLIAPFAPHLGE  742

Query  780  ELWHRL-GRTDSIHQQAWLQVDPTALVLDEITLVIQVLGKTRGTITVPASADKTQLEELA  838
            ELW+ L +  +SI   +W   D + LV +++ +V+Q+ GK ++ + V+    + +L+E+A
Sbjct  743  ELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVA  802

Query  839  RNSDLAQRYLEGKTIKKVIVVPGKLVNFVI  868
              ++  Q  + GK I KVI VP KLVN+VI
Sbjct  803  LANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

764) leuS in NC_020286


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  591 bits (2234),  Expect = 5e-170, Method: Compositional matrix adjust.
 Identities = 386/870 (45%), Positives = 567/870 (66%), Gaps = 47/870 (5%)

Query  5    YNAGEIEQKWQQRWAEWGLDKTPIASDLPKFYALSMFPYPSG-NLHMGHVRNYTITDVIA  63
            Y+   IE KWQ  WA+    KT   +  PKFYAL MFPYPSG  LH+GH   YT TD+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RLKRMQGYQVLHPMGWDAFGLPAENAAIERGIPPKQWTEKNIAQMRAQLQQLGLSIDWER  123
            R+KR QG +VLHPMGWDAFGLPAE+ A++ G  P + T  NIA+ + Q++ LG+S DW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVATCAPDYYRWTQWLFLEFFQAGLAYQKEATVNWDPIDQTVLANEQVDSEGRSWRSGAM  183
            EV T  P+YY+WTQW+F  +++ GLAY+ E  VNW     T +ANE+V ++G S R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  184  VERKLLRQWFLKITDYAEALLNDLEQLTGWPERVKLMQSHWIGKSVGAYLEFPIKDSQEK  243
            V RK +RQW LKIT YAE LL+DLE++ +WPE +K MQ +WIGKS GA + F +KD++  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  244  IAVFTTRPDTVYGVTYVVLAPEHPLTKVVTTAEQQGTVDEFVAMVAKESEIERTAEDKPK  303
            ++VFTTRPDT++G TY VLAPEH+L   +TT++Q  +V ++    +  S++ RT   K K
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEK  302

Query  304  RGVKTGGIAINPFNGEEIPILIADYVLYEYGTGAVMGVPAHDQRDFKFAQDNNLPMQVVI  363
             GV TG+ AINP NG E+P+ IADYVL  YGTGA+M+VPAHD+RD  FA++ NL +  V+
Sbjct  303  TGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL  362

Query  364  IPDDADNSDVNLTVAYTEAGVMVNSAQFTGMASPKAKQAIIKFAEDNDYGRAKVQYRLRD  423
              ++ +++      A+TE G+ +NS  + G+  + A   ++   E ++ G  +V YRLRD
Sbjct  363  EGGNVEEA------AFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  424  WLISRQRYWGCPIPIIHCDDCGAVPVPTKDLPVELPDNVEF--SGRGPSPLAKLEDWINV  481
            WL+SRQRYWG PIPIIH +D  + +VP  +LP+ LP   ++  SG G SPLA++ DW++V
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  482  PCPSCGKPARRETDTMDTFIDSSWYFLRYADAQNTELPFDGEKVAHWLPVDQYVGGIEHA  541
                  K +RRET+TM    +SSWY+LRY D++NTE   D E + +WLPVD YVGG EHA
Sbjct  477  TREDGVK-GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  542  ILHLLYSRFFTKVLADRQLIPVKEPFQKLLTQGMVQGITYKNPTTGKYVPAKDLQTGQQV  601
            +LHLLY+RF  KVL D  ++P KEPFQKL+ QGM+ G +Y++        +++   + + 
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRD--------SRGALVATDK  587

Query  602  IDPKDPK--DPDSGEPLQVFYEKMSKSKFNGVDPQEVLAKYGADTARMFILFKAPPEKDL  659
            ++ +D    + ++GE L+    KMSKS  N V+P++V+ +YGADT R++ +F +P +  +
Sbjct  588  VEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASI  647

Query  660  EWDDADVEGQFRFLNRVWRLVTDYIGDPAGIRFAVRPETLVTNEPLTKAEKDLRRAIHGA  719
             W + ++EG  +FL+RV RL+T                   T+E        L +  + +
Sbjct  648  AWSEEGLEGSRKFLDRVYRLIT-------------------TKEITEENSGALDKVYNET  688

Query  720  IKEVAEDLNDDYQFNTAISEMMKLSNALIAATDLISFPVYQEGIETlllllAPFAPHLTE  779
            +K V+E++ D+ +FNTAI+++M + NA      L  F+ Y  G+   + L+APFAPHL E
Sbjct  689  VKAVTEQV-DQMKFNTAIAQLMVFVNAANKEDKL--FSDYAKGF---VQLIAPFAPHLGE  742

Query  780  ELWHRL-GRTDSIHQQAWLQVDPTALVLDEITLVIQVLGKTRGTITVPASADKTQLEELA  838
            ELW+ L +  +SI   +W   D + LV +++ +V+Q+ GK ++ + V+    + +L+E+A
Sbjct  743  ELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVA  802

Query  839  RNSDLAQRYLEGKTIKKVIVVPGKLVNFVI  868
              ++  Q  + GK I KVI VP KLVN+VI
Sbjct  803  LANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

765) leuS in NC_000911


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  591 bits (2234),  Expect = 5e-170, Method: Compositional matrix adjust.
 Identities = 386/870 (45%), Positives = 567/870 (66%), Gaps = 47/870 (5%)

Query  5    YNAGEIEQKWQQRWAEWGLDKTPIASDLPKFYALSMFPYPSG-NLHMGHVRNYTITDVIA  63
            Y+   IE KWQ  WA+    KT   +  PKFYAL MFPYPSG  LH+GH   YT TD+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RLKRMQGYQVLHPMGWDAFGLPAENAAIERGIPPKQWTEKNIAQMRAQLQQLGLSIDWER  123
            R+KR QG +VLHPMGWDAFGLPAE+ A++ G  P + T  NIA+ + Q++ LG+S DW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVATCAPDYYRWTQWLFLEFFQAGLAYQKEATVNWDPIDQTVLANEQVDSEGRSWRSGAM  183
            EV T  P+YY+WTQW+F  +++ GLAY+ E  VNW     T +ANE+V ++G S R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  184  VERKLLRQWFLKITDYAEALLNDLEQLTGWPERVKLMQSHWIGKSVGAYLEFPIKDSQEK  243
            V RK +RQW LKIT YAE LL+DLE++ +WPE +K MQ +WIGKS GA + F +KD++  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  244  IAVFTTRPDTVYGVTYVVLAPEHPLTKVVTTAEQQGTVDEFVAMVAKESEIERTAEDKPK  303
            ++VFTTRPDT++G TY VLAPEH+L   +TT++Q  +V ++    +  S++ RT   K K
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEK  302

Query  304  RGVKTGGIAINPFNGEEIPILIADYVLYEYGTGAVMGVPAHDQRDFKFAQDNNLPMQVVI  363
             GV TG+ AINP NG E+P+ IADYVL  YGTGA+M+VPAHD+RD  FA++ NL +  V+
Sbjct  303  TGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL  362

Query  364  IPDDADNSDVNLTVAYTEAGVMVNSAQFTGMASPKAKQAIIKFAEDNDYGRAKVQYRLRD  423
              ++ +++      A+TE G+ +NS  + G+  + A   ++   E ++ G  +V YRLRD
Sbjct  363  EGGNVEEA------AFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  424  WLISRQRYWGCPIPIIHCDDCGAVPVPTKDLPVELPDNVEF--SGRGPSPLAKLEDWINV  481
            WL+SRQRYWG PIPIIH +D  + +VP  +LP+ LP   ++  SG G SPLA++ DW++V
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  482  PCPSCGKPARRETDTMDTFIDSSWYFLRYADAQNTELPFDGEKVAHWLPVDQYVGGIEHA  541
                  K +RRET+TM    +SSWY+LRY D++NTE   D E + +WLPVD YVGG EHA
Sbjct  477  TREDGVK-GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  542  ILHLLYSRFFTKVLADRQLIPVKEPFQKLLTQGMVQGITYKNPTTGKYVPAKDLQTGQQV  601
            +LHLLY+RF  KVL D  ++P KEPFQKL+ QGM+ G +Y++        +++   + + 
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRD--------SRGALVATDK  587

Query  602  IDPKDPK--DPDSGEPLQVFYEKMSKSKFNGVDPQEVLAKYGADTARMFILFKAPPEKDL  659
            ++ +D    + ++GE L+    KMSKS  N V+P++V+ +YGADT R++ +F +P +  +
Sbjct  588  VEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASI  647

Query  660  EWDDADVEGQFRFLNRVWRLVTDYIGDPAGIRFAVRPETLVTNEPLTKAEKDLRRAIHGA  719
             W + ++EG  +FL+RV RL+T                   T+E        L +  + +
Sbjct  648  AWSEEGLEGSRKFLDRVYRLIT-------------------TKEITEENSGALDKVYNET  688

Query  720  IKEVAEDLNDDYQFNTAISEMMKLSNALIAATDLISFPVYQEGIETlllllAPFAPHLTE  779
            +K V+E++ D+ +FNTAI+++M + NA      L  F+ Y  G+   + L+APFAPHL E
Sbjct  689  VKAVTEQV-DQMKFNTAIAQLMVFVNAANKEDKL--FSDYAKGF---VQLIAPFAPHLGE  742

Query  780  ELWHRL-GRTDSIHQQAWLQVDPTALVLDEITLVIQVLGKTRGTITVPASADKTQLEELA  838
            ELW+ L +  +SI   +W   D + LV +++ +V+Q+ GK ++ + V+    + +L+E+A
Sbjct  743  ELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVA  802

Query  839  RNSDLAQRYLEGKTIKKVIVVPGKLVNFVI  868
              ++  Q  + GK I KVI VP KLVN+VI
Sbjct  803  LANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

766) Ferpe_0048 in NC_017095


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  591 bits (2233),  Expect = 6e-170, Method: Compositional matrix adjust.
 Identities = 385/856 (45%), Positives = 547/856 (64%), Gaps = 67/856 (7%)

Query  4    YRPQEIEPKWQKVWEEKKVFETPQYSEKPKYYTLIMFPYPSGT-LHVGHVKNYTIGDIVA  62
            Y    IEPKWQ  W ++  F T   + KPK+Y+L MFPYPSG+ LHVGH   YT  DI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRMQGYNVLHPFGYDAFGLPAENAAIAHKIHPKKWTMDNINTIRGQIKKMGISYDWNR  122
            R+KR QG NVLHP G DAFGLPAE+ A+    +P   T +NI  ++ QI+ +G+SYDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVITCNEDYYKWTQWIFLKLYEAGLAYKKPGAVNWCPSCQTVLANEQV-KDGKCERCGTT  181
            EV T + +YYKWTQWIF KLYE GLAY    +VNW     T +ANE+V  DG  ER G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VTMKHLEQWYFKITDYAEKLLEGLDRLPGWPEHVKTMQRNWIGKSTGAEVDFPVEGLDKK  241
            V  K + QW +KIT YAE+LLE+L+ + +WPE +K MQRNWIGKSTGA+V F V + DK 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  242  IRIFTTRPDTIYGVTFMAIAPESPLVLELVTDEKRKEVEEFLAKVAHEDRFKRTSLEAKK  301
            + +FTTRPDT++G T+  +APE +LV  + T ++   V ++  + +    + RT L   K
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEK  302

Query  302  EGVFLGRYAINPLTGERIPIYVANYILYEYGTGAIMAVPAHDKRDFDFAKAYGLPIKQVI  361
             GV  G YAINP+ G  +P+ +A+Y+L  YGTGAIMAVPAHD RD +FAK + L I  V+
Sbjct  303  TGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL  362

Query  362  KPKEGDWNIEEAPYEDEGIMINSGPFNGLDSKKGIEEVTKYIEEKGFGKRSVQYKLRDWL  421
               EG+ N+EEA++ ++G+ INS+ ++GLD   +I  +   +E  G G+ +V Y+LRDWL
Sbjct  363  ---EGG-NVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWL  418

Query  422  ISRQRYWGAPIPIIYCDKCGIVPVPEKDLPVKLPENVEFLP--TGQSPLTLSEEFKHTTC  479
            +SRQRYWG PIPII  +     +VPE +LP+ LP   ++ P  TG+SPL+   +  + T 
Sbjct  419  FSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTR  478

Query  480  PKCGGPARREVETMDTFVDSSWYFLRYVNPKLEDKPFDTNDVNYWLPVDQYIGGVEHAVL  539
               G  +RRE +TM    +SSWY+LRY++P   +K  D + ++ WLPVD Y+GG EHAVL
Sbjct  479  ED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVL  537

Query  540  HLLYSRFITKVLHDLGYVGFDEPFQNLFTQGMI----YKDGW------------------  577
            HLLY+RF  KVL DLG V   EPFQ+LF QGMI    Y+D++                  
Sbjct  538  HLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFH  597

Query  578  ------------KMSKSKGNVVSPDDMIEKYGADTLRMYILFMAPPEKDAEWSDAGIEGV  625
                        KMSKS  NVV+PDD++E+YGADTLR+Y +FM+P +    WS+ G+EG 
Sbjct  598  VETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGS  657

Query  626  NRFVKRLWNNYYKMLDIINSQDAEESEFGKEERALRRKLHAMIKKIKEDIEGGFKFNTAI  685
             +F+ R+    Y++   I +++  E + G    AL +  +  +K + E+++   KFNTAI
Sbjct  658  RKFLDRV----YRL---ITTKEITEENSG----ALDKVYNETVKAVTEQVD-QMKFNTAI  705

Query  686  AGLMEFNNQLSDYLETAQNPNKKLLREIAEKIALIISPFAPHMAEEMWHDLGKETLIVE-  744
            A LM F N        A N + KL+ + A  +  +I+PFAPH++EE+W+ L      +  
Sbjct  706  AQLMVFVN--------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISY  757

Query  745  ERWPDYDEEALKEEEITIAVQVNGKVRGRITVPADSSEDQIKEKAV--ENVKKLVEGKQI  802
              WP YDE  L E+++ I VQ++GKV++++ V+ D S ++++E A+  E+V+  + GK+I
Sbjct  758  VPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDI  817

Query  803  VNIFYVPGKLVNIVVK  818
            ++++ VP KLVNIV+K
Sbjct  818  IKVIAVPNKLVNIVIK  833

767) leuS in NC_003272


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  591 bits (2233),  Expect = 6e-170, Method: Compositional matrix adjust.
 Identities = 379/873 (44%), Positives = 583/873 (67%), Gaps = 50/873 (5%)

Query  5    YNPATLEEKWQKTWVELGLDKTQTQSNKPKFYALSMFPYPSGS-LHMGHVRNYTITDVIA  63
            Y+ +++E KWQ  W +    KT T+++KPKFYAL MFPYPSG+ LH+GH   YT TD+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RLKRMQGYRVLHPMGWDAFGLPAENAAIDRGVPPAKWTYQNITQMRQQLQRLGLSIDWDS  123
            R+KR QG  VLHPMGWDAFGLPAE+ A+D G  PA  T +NI++ ++Q++ LG+S DWD 
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVATCSPDYYKWTQWIFLQFLQAGLAYQKEAAVNWDPIDQTVLANEQVDNEGRSWRSGAI  183
            EV T  P+YYKWTQWIF ++ + GLAY+ E +VNW     T +ANE+V  +G S R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  184  VERKLLRQWFLKITDYAEELLNDLDKLTGWPERVKLMQANWIGKSSGAYLEFPIVGSNEK  243
            V RK +RQW LKIT YAE LL+DL+ + +WPE +K MQ NWIGKS+GA + F + +++  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  244  IAVYTTRPDTVYGVSYVVLAPEHPLtkqvttktqqaavDTFIQEVTNQSELERTAEDKPK  303
            ++V+TTRPDT++G +Y VLAPEH+L   +TT  Q  AV  + ++ + +S+L RT   K K
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEK  302

Query  304  RGIATGGKAINPFTGEEVPIWIADYVLYEYGTGAVMGVPAHDVRDFKFAQRYDLPIDFVI  363
             G+ TG+ AINP  G E+P+WIADYVL  YGTGA+M+VPAHD RD  FA++++L I  V+
Sbjct  303  TGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL  362

Query  364  AAPDDVAGFDLSPTSeteevtqvvqIEYNQAYTEPGILINSGAFTGMTSTDAKQAIVKYA  423
             + +                     +E + A+TE G+ INS+ + G+  + A   +V   
Sbjct  363  EGGN---------------------VE-EAAFTEDGLHINSDFLDGLDKASAIAKMVEWL  400

Query  424  TEKGFGKERIQYRLRDWLISRQRYWGAPIPVIHCPNCGIVPVPDKDLPVILP--EEVEFT  481
               G G+E + YRLRDWL+SRQRYWG PIP+IH  +    +VP+ +LP++LP   ++  +
Sbjct  401  EAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPS  460

Query  482  GRGGSPLAQLESWVNVPCPTCGTPAKRETDTMDTFIDSSWYFLRFTDARNEAQVFESAKT  541
            G G SPLA++  W++V     G  ++RET+TM    +SSWY+LR+ D++N  ++ +    
Sbjct  461  GTGESPLANVTDWLEVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELL  519

Query  542  NDWMPVDQYVGGIEHAILHLLYSRFFTKVLRDRGLLNFDEPFERLLTQGMVQGLTYFNPN  601
            ++W+PVD YVGG EHA+LHLLY+RF  KVL D G++   EPF++L+ QGM+ G +Y    
Sbjct  520  KQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY----  575

Query  602  KGGKDKWVPSHLVNPNDPR--DPQTGEPLQRLYATMSKSKGNGVAPEDVIAKYGVDTARM  659
            +++++  V+++ V+  D    + +TGE L++  A MSKS  N V P+DV+ +YG DT R+
Sbjct  576  RDSRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRV  635

Query  660  FILFKAPPEKDLEWDEADVEGQFRFLNRVWRLVTDYVASGVNPKNKSGELSKSEKDLRRA  719
            + +F +P +  + W E ++EG  +FL+RV RL+T   +  +   N ++        L + 
Sbjct  636  YEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLIT---TKEITEENSGA--------LDKV  684

Query  720  IHTAIQSVTEDLEDDYQFNTAISELMKLSNALTDANGKDSRVYAEGIKTLVVLLAPFAPH  779
             + ++++VTE++ D+ +FNTAI++LM     + +A  K+ +++++  K +V L+APFAPH
Sbjct  685  YNETVKAVTEQV-DQMKFNTAIAQLM----VFVNAANKEDKLFSDYAKGFVQLIAPFAPH  739

Query  780  IAEELWR-LLGNSESVHTQTWPAFDPAALVADEITLVIQVNGKKRADIQVPSQADKAELE  838
            ++EELW+ L +++ES+    WP++D + LV +++ +V+Q++GK +A + V+ +  + EL+
Sbjct  740  LGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQ  799

Query  839  KYARESEVVQRHLEGKEIKKVIVVPGKLVNFVV  871
              A  +E VQ ++ GK+I KVI VP KLVN+V+
Sbjct  800  EVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

768) Dtur_1563 in NC_011661


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  590 bits (2227),  Expect = 2e-169, Method: Compositional matrix adjust.
 Identities = 379/847 (45%), Positives = 544/847 (65%), Gaps = 52/847 (6%)

Query  1    MKRYNPQEIEPKWQKKWNEDKLYHVTERSDKQKYYTLVMFPYPSG-DLHMGHMRNYTIGD  59
            M  Y+   IEPKWQ  W ++  +     + K K+Y+L MFPYPSG +LH+GH   YT  D
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  60   VVARYYTMKGYNVLNPMGWDAFGQPAENAAIKNKVHPKEWTYRNIARMKEQLFKMGVVYD  119
            +++R+   +G NVL+PMGWDAFG PAE+ A+    +P E T  NIA  K Q+  +G  YD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  120  WDREVTACAPDYYKWTQWIFLKLYERGLAYRKKAPANWCPTCKTVLANEEVI-DGRCWRC  178
            WDREV +  P+YYKWTQWIF KLYE+GLAY    P NW     T +ANEEV+ DG   R 
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  179  KTPVERREFEQWFFKITEYAEALLNDLDTLEHWPEKVKLMQKNWIGKSEGLEFYFEVQGM  238
              PV R+   QW +KIT YAE LL+DL+ ++ WPE +K MQ+NWIGKS G +  F V++ 
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDT  239

Query  239  DEKIYVYTTRPDTIYGVTFVVLAPEHPLVEKITTPEHLDKVREYIRQAKNKSELERLTSE  298
            D  + V+TTRPDT++G T+ VLAPEH+LV+ ITT+++ + V +Y RQA  KS+L R    
Sbjct  240  DKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA  299

Query  299  KEKTGVFTGSYAIHPLTKKPIPIYVADYVLATYGTGAIMAVPAHDSRDYDFAVKFNLPII  358
            KEKTGV TGSYAI+P+  K +P+ +ADYVLA+YGTGAIMAVPAHD RD +FA +FNL II
Sbjct  300  KEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDII  359

Query  359  PVITPDPNKAPELPYEEEGIMINSGEYNGMKSSEFWKLIVEKFENLGIGKKKVQYRLRDW  418
            PV+  +  +  E ++ E+G+ INS+  +G+  +     +VE +E  G+G+ +V YRLRDW
Sbjct  360  PVL--EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDW  417

Query  419  LISRQRYWGAPIPIIYCPNCGIVPVPYEDLPVELPELSDFEPTGTGESPLAKVPEFVNTK  478
            L+SRQRYWG PIPII   +    +VP  +LP+ LP   D+ P+GTGESPLA+V + ++  
Sbjct  418  LFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT  477

Query  479  CPKCGSPARRETDTLATFVDSSWYYFRYTDPHNDKEPFSRNKAEYWMPVDQYTGGIEHAI  538
                G  +RRET+T++   +SSWYY+RY DPHN       +    W+PVD Y GG EHA+
Sbjct  478  RED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  539  LHLLYSRFITKVLYDAGYSPVREPFKRLFTQGMV----YKDGQI----------------  578
            LHLLY+RF  KVLYD G  P +EPF++LF QGM+    Y+D++                 
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFF  596

Query  579  --------------MSKSLGNIVSVDYMVENYGADTARLFILFVAPPEVDIEWSDEGVEG  624
                          MSKSL N+V+ D +VE+YGADT R++ +F++P +  I WS+EG+EG
Sbjct  597  HVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEG  656

Query  625  ANRFLNRFWRLVLEDAEVEPKIDEEQEKLIKRKLHKTIKKVTEDIENFKFNTAIAAIMEL  684
            + +FL+R  RL+         I EE+   + +  + T+K VTE++++ KFNTAIA +M +
Sbjct  657  SRKFLDRVYRLI-----TTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVF  711

Query  685  TNLLFEHKRSFGRTPAFEEAIRTSILLLSPFVPHITEELWVEL-GNEYSVHMQKWPSYDP  743
             N    + + F+      +  +  + L++PF PH+ EELW  L ++  S+    WPSYD 
Sbjct  712  VNAANKEDKLFS------DYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDE  765

Query  744  EMIKEEVVTVVIQINGRVRDRIDVNADATQEEILKLALERDNVKRYLDNKEIKKIVYVPG  803
              + E+ V +V+QI+G+V+ ++ V  D ++EE+  +AL  ++V+  +  K+I K++ VP 
Sbjct  766  SKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPN  825

Query  804  KILSLYV  810
            K++++ +
Sbjct  826  KLVNIVI  832

769) Nos7107_4769 in NC_019676


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  590 bits (2227),  Expect = 2e-169, Method: Compositional matrix adjust.
 Identities = 382/874 (44%), Positives = 577/874 (67%), Gaps = 52/874 (5%)

Query  17   YSPAAIEEKWQKSWAELGLDNTLTENNKPKFYALSMFPYPSGS-LHMGHVRNYTITDVIA  75
            Y  +AIE KWQ  WA+    +T T+ +KPKFYAL MFPYPSG+ LH+GH   YT TD+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  76   RLKRMQGYRVLHPMGWDAFGLPAENAAIDRGVPPAKWTYQNIAQMRQQLQRLGLSIDWES  135
            R+KR QG  VLHPMGWDAFGLPAE+ A+D G  PA  T +NIA+ ++Q++ LG+S DW+ 
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  136  EVATCSPDYYKWTQWIFLQFLQAGLAYQREAAVNWDPIDQTVLANEQVI-DGRSWRSGAL  194
            EV T  P+YYKWTQWIF ++ + GLAY+ E +VNW     T +ANE+V+ DG S R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  195  VERKLLRQWFFKITDYAEELLNDLDKLTGWPERVKLMQANWIGKSVGAYLEFPIVGMDEK  254
            V RK +RQW +KIT YAE LL+DL+ + +WPE +K MQ NWIGKS GA + F + + D  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  255  IGVYTTRPDTVFGVSYVVLAPEHPLTKRVTTKDQQAAVEAFITEVSHQSELERTAEDKPK  314
            + V+TTRPDT+FG +Y VLAPEH+L   +TT DQ  AV  +  + S +S+L RT   K K
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEK  302

Query  315  RGVPTGGKAINPFTGDEVQILIADYVLYEYGTGAVMGVPAHDVRDFKFAKAYDLPIDVVI  374
             GV TG+ AINP  G E+ + IADYVL  YGTGA+M+VPAHD RD  FAK ++L      
Sbjct  303  TGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNL------  356

Query  375  AAPEDVDGFDLTPASENEEVTQLIQIEYHEAYTEPGVLINSGQFTGMNSVEAKAAIVQYA  434
                     D+ P  E  +V +        A+TE G+ INS+ + G++   A A +V+  
Sbjct  357  ---------DIIPVLEGGNVEE-------AAFTEDGLHINSDFLDGLDKASAIAKMVEWL  400

Query  435  QEQGFGKERIQYRLRDWLISRQRYWGAPIPVIHCPNCGIVPVPDKDLPVQLP--EEVEFT  492
            + +G G+E + YRLRDWL+SRQRYWG PIP+IH  +    +VP+ +LP+ LP   ++  +
Sbjct  401  EAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPS  460

Query  493  GRGGSPLTQLESWVNVPCPTCGTPAKRETDTMDTFIDSSWYFLRFTDAKNEQQVFDPSKT  552
            G G SPL+++  W++V     G  ++RET+TM    +SSWY+LR+ D+ N +++ D    
Sbjct  461  GTGESPLANVTDWLEVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELL  519

Query  553  NDWMPIDQYVGGIEHAILHLLYSRFFTKVLRDRGLLNFDEPFARLLTQGMVQGLTYMNPN  612
            ++W+P+D YVGG EHA+LHLLY+RF  KVL D G++   EPF +L+ QGM+ G +Y    
Sbjct  520  KQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY----  575

Query  613  KGGKDKWVPSHLVNPADPR--DPQTGEPLQRLYATMSKSKGNGVAPEDVISKYGIDTARM  670
            +++++  V+++ V+  D    + +TGE L++  A MSKS  N V P+DV+ +YG DT R+
Sbjct  576  RDSRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRV  635

Query  671  FILFKAPPEKDLEWDEADVEGQFRFLNRVWRLVTDYAAAGVSRKQAQLADLSKPEKELRR  730
            + +F +P +  + W E ++EG  +FL+RV RL+T   +  ++  ++           L +
Sbjct  636  YEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLIT---TKEITEENSG---------ALDK  683

Query  731  AIHTAIKSVTEDLEDEYQFNTAISELMKLSNSLTDSDCKNSPIYAEGIQSLVALLAPFAP  790
              + ++K+VTE++ D+ +FNTAI++LM     + ++  K+  ++++  +++V L+APFAP
Sbjct  684  VYNETVKAVTEQV-DQMKFNTAIAQLM----VFVNAANKEDKLFSDYAKGFVQLIAPFAP  738

Query  791  HIADELWH-LLGNKNSVHTQTWPAFDAAALIADEITLVIQINGKKRADIQVPAQADKAEL  849
            H+++ELW+ L ++ +S+    WP++D + L+ +++ +V+QI+GK +A + V+ +  + EL
Sbjct  739  HLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREEL  798

Query  850  EKYARESEVVQRHLEGKEIKKVIVVPGKLVNFVV  883
            +  A  +E VQ ++ GK+I KVI VP KLVN+V+
Sbjct  799  QEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

770) LeuS in NC_015737


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  590 bits (2230),  Expect = 9e-170, Method: Compositional matrix adjust.
 Identities = 397/840 (48%), Positives = 559/840 (67%), Gaps = 51/840 (6%)

Query  5    YNHREVEQKWRKIWKEKPV--NVNDGKKPKYYCLDMFPYPSGNGLHVGHWRGYVISDVWS  62
            Y+H  +E KW+ +W ++       D+ KPK+Y LDMFPYPSG GLHVGH  GY  +D+ S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKLQQGHYIIHPMGWDAFGLPAENYAIKMGTHPAITTASNIKNIKRQINEISALYDWDM  122
            R+K  QGH ++HPMGWDAFGLPAE+YA+  G +PA  TA NI N+KRQIN ++  YDWD 
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVNTTDPSFYKWTQWIFVQMFKKGLAYQKEMPINWCPSCKTGLANEEVV-NGKCERCGAD  181
            EVNTTDP++YKWTQWIF +++ KGLAY+ E+P+NW     T++ANEEV+ +G  ER G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VTKKNLNQWMLKITdyadrllddldkldWPEKVKKMQTDWIGKSYGAEVNFRVDGSDRTI  241
            V +K + QWMLKIT YA+RLL+DL+ +DWPE +K MQ +WIGKS GA+V F+V ++D+ +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  TVYTTRPDTLHGATFMVLAPEHAMASELATPEQKGAVEDYIYQTSLKSSVDRMQ-DKEKT  300
            TV+TTRPDTL GAT+ VLAPEHA+   ++T++Q  AV DY  Q+SLKS + R +  KEKT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  301  GVFTGSYAINPINGKKVPIWLADYVLADYGTGAVMCVPAHDDRDFEFAVKYGIPVVQVIA  360
            GV TGSYAINP+NGK +P+W+ADYVLA YGTGA+M VPAHD+RD EFA ++ + ++ V+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL-  362

Query  361  KDGKEIEHMTEPYTEARGTMINSGSWNGMESSELKKKAPHIIEEMGCGRATTNYKLRDWV  420
             +G ++E+   ++TE  G  INS+  +G++ +    K  + +E  G G     Y+LRDW+
Sbjct  363  -EGGNVEE--AAFTED-GLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWL  418

Query  421  FSRQRYWGEPIPIVHCPHCGAvpvpeeelplllpeveSYQPTGTGESPLAAITDWVNTTC  480
            FSRQRYWGEPIPI+H  +  + +VPE ELPL+LP     +P+GTGESPLA +TDW++ T 
Sbjct  419  FSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTR  478

Query  481  PCCGRPAKRETNTMPQWAGSSWYFLRYIDNKNDKELVSREKADKYLPVDMYIGGVEHAVL  540
                + ++RETNTMPQWAGSSWY+LRYID  N   L   E   + LPVD+Y+GG EHAVL
Sbjct  479  EDGVK-GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVL  537

Query  541  HLLYSRFYTKFLYDIGVIDFDEPFKKLFNQGMITG-------------------------  575
            HLLY+RF  K LYD+GV+   EPF+KLFNQGMI G                         
Sbjct  538  HLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFH  597

Query  576  --------KNGIKMSKSKGNVISPDDLVRDYGCDSLRLYELFVGPPELDSEWDDRGIDGV  627
                    +   KMSKS  NV++PDD+V +YG D+LR+YE+F+GP +    W + G++G 
Sbjct  598  VETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGS  657

Query  628  YRFISKFWKLVMDQKDANAAPTKELVKLRHKLIYDITTRLESFSLNTVISGFMEYNNKLN  687
             +F+ +  +L+   K+     +  L K+ +  +  +T +++   +NT I+ +M +   +N
Sbjct  658  RKFLDRVYRLITT-KEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVF---VN  713

Query  688  DLAKKGGVDKETLETFVVLLSPFAPHISEELYHQL-GHEDSVFTAGWPSYDEEAMKDDEK  746
               K + +  +    FV L++PFAPH++EEL + L +  +S+    WPSYDE  + +++ 
Sbjct  714  AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDV  773

Query  747  EIAVQINGKTKGVVTIa---adaskedalaaakeVLGDKLTGTIVKEIYVPGRIVNIVQK  803
            EI VQI+GK K+ + +A   +    ++   A   V ++     I+K I VP ++VNIV K
Sbjct  774  EIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

771) leuS in NC_017464


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  589 bits (2226),  Expect = 2e-169, Method: Compositional matrix adjust.
 Identities = 389/861 (46%), Positives = 551/861 (64%), Gaps = 74/861 (8%)

Query  3    YPFDLIEAKWQKFWEENKVFKTDFNDISKKLYTLVMFIYPSGAKLHIGHWYNYGPTDSWA  62
            Y    IE+KWQ FW +N  FKT+ +    K+Y+L MF YPSGA LH+GH   Y +TD  +
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RFKKLQGYNVFEPMGYDAFGLPAENYAIKTGIHPFDSTMQNINDIRQQLKRMGCMYDWDA  122
            RFK+ QG NV++PMG DAFGLPAE+YA+ TG +P + T +NI ++++Q++ +G  YDWD 
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  ELMTCVPEYYKWNQWIFLQMYNRGLAYRKNAPVNWCPKDQTVLANEQV-QDGACERCGTP  181
            E+ T  P+YYKW QWIF ++Y++GLAY  + PVNW     T +ANE+V  DG+ ER G P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VIQKNLYQWFFKITDYAEELLQGLDKINWPEKTKTMQRNWIGKSEGAEVYFKVVGIDDEI  241
            V++K + QW +KIT YAE LL++L+ ++WPE  K MQRNWIGKS GA+V FKV + D ++
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  242  KVFTTRPDTLFGVTYVVLAPEHPLVDKITKDEFRKSVEDYRDSIKSLTEIERTSTVKEKT  301
             VFTTRPDTLFG TY VLAPEH+LVD IT  +   +V DY+      +++ RT   KEKT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  302  GVPTGAFAINPVNGEKVPVWIADYALITYGTGAVMAVPAHDERDFEFASKFNLPIKKVIL  361
            GV TG++AINPVNG  +PVWIADY L +YGTGA+MAVPAHDERD EFA +FNL I  V L
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV-L  362

Query  362  QNGTNESDELKSAFTEVGIMINSGQFNGLKSDEGIQKVIDYLEQNEFGKRKINYRLRDWL  421
            + G  E     +AFTE G+ INS+ ++GL    +I K+++ LE +  G+ ++ YRLRDWL
Sbjct  363  EGGNVEE----AAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWL  418

Query  422  ISRQRYWGTPIPIIHCPKCGEVPVDEKDLPVELPYDVDFQPG--GESPLARNEKFINIKC  479
            +SRQRYWG PIPIIH       +V E +LP+ LP   D++P+  GESPLA     +++  
Sbjct  419  FSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTR  478

Query  480  PKCGSDAKRDPDTMDTFVDSSWYYLRYLNPRISDAPFDVELAKKWTPVDMYVGGAEHATM  539
               G  ++R+ +TM    +SSWYYLRY++P+ ++   D EL K+W PVD+YVGGAEHA +
Sbjct  479  ED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVL  537

Query  540  HLLYARFVHKFLRDIGLVNSDEPFQTLVHQGTI---------------------------  572
            HLLYARF HK L D+G+V + EPFQ L +QG I                           
Sbjct  538  HLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFH  597

Query  573  -------TNQGAKMSKSKGNVVNPDDFTSKYGSDVFRMYLMFMGPYDQGGDWSDKGISGV  625
                    +  AKMSKS  NVVNPDD   +YG+D +R+Y MFMGP D +  WS+ G+ G 
Sbjct  598  VETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGS  657

Query  626  DRFVQRTYELFNQHKELNKSVKSKSKYEITSLSDSEKKIYRKVNQTLKKFNEEIENFRFN  685
             +F++R Y L+       K +   +       S++  K+Y   N+T+K   E++++ +FN
Sbjct  658  RKFLDRVYRLIT-----TKEITEEN-------SGALDKVY---NETVKAVTEQVDQMKFN  702

Query  686  TAIASlmellnelknlehcnDEIKVYA--LERFAFMLAPVAPHLGEECWQTLGKENSIYQ  743
            TAIA        +  ++  N E K+++     F  ++AP APHLGEE WQ+L        
Sbjct  703  TAIAQ------LMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGE---  753

Query  744  KPVTF----DFDKNALIEDTVNLAVQVNGKLRATIEVPLNSEQEAVKPIIFADGRVMKFV  799
             ++++     +D + L+E+ V++ VQ++GK++A + V+ +  +E ++ + +A+ +V   +
Sbjct  754  -SISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEI  812

Query  800  DGKKIVKEIFVKNKIYNIVVK  820
             GK I+K I V NK+ NIV+K
Sbjct  813  AGKDIIKVIAVPNKLVNIVIK  833

772) Dacsa_2623 in NC_019780


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  589 bits (2226),  Expect = 2e-169, Method: Compositional matrix adjust.
 Identities = 383/852 (45%), Positives = 575/852 (68%), Gaps = 29/852 (3%)

Query  7    YNPSEIEPKWQQNWLETEIDRASEDKSKPKFYALSMFPYPSG-NLHMGHVRNYVITDVMA  65
            Y+ + IEPKWQ  W + +  +++ D SKPKFYAL MFPYPSG  LH+GH   Y  TD+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  66   RWRRMQGYRVLHPMGWDAFGLPAENAAIDRGIHPAQWTEKNIqqmkqqlqqlglslDWSR  125
            R +R QG  VLHPMGWDAFGLPAE+ A+D G +PA+ T  NI + K+Q++ LG+S DW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  126  EVATCSPDYYKWTQWIFLQFFQAGLAYQKESAVNWDPIDQTVLANEQVDGEGKSWRSGAK  185
            EV T  P+YYKWTQWIF ++++ GLAY+ E +VNW     T +ANE+V  +G S R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  186  VERKLLKQWFLKITEYAEELLNDLEKLPGWPDRVKLMQENWIGKSVGAYLEFPIIGIENK  245
            V RK ++QW LKIT YAE LL+DLE + +WP+ +K MQ NWIGKS GA + F + + ++ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  246  IGVFTTRPDTVYGVTYVVLAPEHPLTPKVTTSDQKPAVEAFIQEVTNESEQERTAEDKPK  305
            + VFTTRPDT++G TY VLAPEH+L   +TTSDQ  AV  + ++ +  S+  RT   K K
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEK  302

Query  306  RGIPTGGKAINPFTGEEIPILIADYVLYEYGTGAVMGVPAHDARDFQFATQNQLPIKQVI  365
             G+ TG+ AINP  G E+P+ IADYVL  YGTGA+M+VPAHD RD +FA Q +L I  V+
Sbjct  303  TGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL  362

Query  366  VPEGEAVSDTLENAYTEAGTIVNSGQFDGLNSVEGKQVIIDHAEKQGWGKARIQYRLRDW  425
              EG  V ++   A+TE G  +NS+ +DGL+   +   +++  E +G G+  + YRLRDW
Sbjct  363  --EGGNVEEA---AFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDW  417

Query  426  LISRQRYWGAPIPIIHCPSCGAVPVPDKDLPVELP--EDIEFTGRGGSPLTQLESWLNVS  483
            L+SRQRYWG PIPIIH     + +VP+ +LP+ LP   DI  +G G SPL+++  WL+V+
Sbjct  418  LFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT  477

Query  484  CPSCGEAAKRETDTMDTFIDSSWYFLRYTDANNIEEAFNQEKVNDWMPVDQYVGGIEHAI  543
                G  ++RET+TM    +SSWY+LRY D++N E   ++E +++W+PVD YVGG EHA+
Sbjct  478  RED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  544  LHLLYSRFFTKVLRDRGLLNCDEPFQRLLTQGMVQGMTYKNPKTGKYIPSQEVNPDDPK-  602
            LHLLY+RF  KVL D G++   EPFQ+L+ QGM+ G +Y++++ G  ++++ V+  D   
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSR-GALVATDKVEKRDGSF  595

Query  603  -DPNTGDELSVFFEKMSKSKYNGVDPLEVLDKYGADTARMFILFKAPPEKDLEWDSADVE  661
             + +TG+EL     KMSKS  N V+P +V+++YGADT R++ +F +P +  + W   ++E
Sbjct  596  FHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLE  655

Query  662  GQFRFLNKVWRLVMEFVEQNEVIDQNADLSKAEKDLRRAIHTAIKSISEDLAGDYQFNTA  721
            G  +FL++V RL    +  +E+ ++N++       L +  + ++K+++E++ ++ +FNTA
Sbjct  656  GSRKFLDRVYRL----ITTKEITEENSG------ALDKVYNETVKAVTEQV-DQMKFNTA  704

Query  722  VSELMKLNNALNEAKCKTSPVYQEGIEALVKLLAPFAPHITEELWHAF-GHKDSIHQQKW  780
            +++LM     + +A  K   ++ +   ++V+L+APFAPH+ EELW+A+ +  +SI    W
Sbjct  705  IAQLM----VFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPW  760

Query  781  LEADPDALTVDEINLVIQIKGKTRGTIPVPANASREELEKYARESDAAQRYLEGKEIKKV  840
               D   L  +++++V+QIKGK ++ + V+ + SREEL+  A  ++  Q  + GK+I KV
Sbjct  761  PSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKV  820

Query  841  IVVPGKLVNFVV  852
            I VP KLVN+V+
Sbjct  821  IAVPNKLVNIVI  832

773) leuS in NC_012563


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  589 bits (2224),  Expect = 3e-169, Method: Compositional matrix adjust.
 Identities = 384/847 (46%), Positives = 544/847 (65%), Gaps = 59/847 (6%)

Query  6    TKIDEKWQKKWEENSLYKFNNENLDKKLYVLEMFSYPSGSKLHAGHWFNYGPVDSWARFK  65
            T I+ KWQ  W +N  +K   +    K+Y L+MF+YPSG+ LH GH   Y + D  +RFK
Sbjct  7    TAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSRFK  66

Query  66   RMQGYNVFQPMGFDAFGLPAENYAIKTGIHPKDSTFKNIETMETQLKAMGAMFNWENEVI  125
            R QG NV++PMG DAFGLPAE+YA+ TG +P + T  NI     Q++A+G  ++W+ EV 
Sbjct  67   RAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDREVN  126

Query  126  TCSPDYYKWTQWLFLKLYEKGLAYKKKAPVNWCPSCNTVLANEQVL-DGKCERCDSNVDK  184
            T  P+YYKWTQW+F KLYEKGLAY    PVNW     T +ANE+VL DG  ER +  V +
Sbjct  127  TTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVR  186

Query  185  KNLEQWFLKITDYAdellekldeldWPEKTKAMQKHWIGKSVGAEVAFNVADSDLSFNVF  244
            K + QW LKIT YA+ LLE L+E+DWPE  K MQ++WIGKS GA+V+F+V D+D  F VF
Sbjct  187  KPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVF  246

Query  245  TTRVDTLFGVTYVVLAPENDLVDKLTTPENKAEVESYKTQAKNQSDIERQSITREKTGVF  304
            TTR DTLFG TY VLAPE+ LVD +TT+++   V  YK QA  +SD+ R  +++EKTGV 
Sbjct  247  TTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVW  306

Query  305  SGSYAINPINGKKVPIWIGDYVLNTYGTGCVMAVPAHDERDFAFATKYNLPIERVIEGG-  363
            +GSYAINP+NGK +P+WI+DYVL +YGTG +MAVPAHDERD  FA ++NL I  V+EGG 
Sbjct  307  TGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGN  366

Query  364  -DSLPYTEYGKMVNSGEFDGLFGNKAKEAVISKLESMNLGRKKINYRLRDWLVSRQRYWG  422
             +  ++TE G  +NS+ +DGL    A   ++  LE+  +G  ++ YRLRDWL SRQRYWG
Sbjct  367  VEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWG  426

Query  423  APIPIVYCEKCGTVEVPMEQLPVELPYNVQFSPDGK--SPLSKCDEFVNTTCPKCGGPAK  480
             PIPI+  E   +  VP  +LP+ LP   ++ P G   SPL++  + ++ T    G  ++
Sbjct  427  EPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED-GVKGR  485

Query  481  READTLDTFVCSSWYYLRYPDNKNSEAAFNPELINKMLPVDKYVGGPEHACMHLLYARFI  540
            RE++T+     SSWYYLRY D  N+E   + EL+++ LPVD YVGG+EHA +HLLYARF 
Sbjct  486  RETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFW  545

Query  541  TKALRDMGYLNFDEPFLSLTHQGLILGP----------------------------DGL-  571
             K L D+G +   EPF  L +QG+ILG                             + L 
Sbjct  546  HKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEELE  605

Query  572  ----KMSKSKGNTISPDDYIKEFGADVFRMYLMFGFDYTEGGAWSDDAIKSIGKFVDRVE  627
                KMSKS  N ++PDD + ++GAD +R+Y MF      + AWS++++ +  KF+DRV 
Sbjct  606  QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVY  665

Query  628  RILENAREEIKNSKDNKSTMDKDEKELNYVRHHSIKSITEDIDKMQFNTSIARLMEFTNA  687
            R++             K   + +   L+ V ++++K++TE++D+M+FNT+IA+LM F NA
Sbjct  666  RLI-----------TTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNA  714

Query  688  LSKYLGIDAIKNALFLRESIIDFITLLAPFAPHFAEEQWE-LIGINSSIFNEKWPEFDPK  746
             +K        + LF  +   +F+ L+APFAPH++EE W+ L +   SI    WP +D  
Sbjct  715  ANK-------EDKLF-SDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDES  766

Query  747  ALIKDEVEIAVQVNGKIRAKINISTSSSEDEIKESALNNEDIKNSIGDKEIKKVIVIKNR  806
             L+ ++VEI VQ++GK++AK+ ++   S +E++E AL NE ++  I++K+I KVI + N+
Sbjct  767  KLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNK  826

Query  807  LVNIVAK  813
            LVNIV K
Sbjct  827  LVNIVIK  833

774) leuS in NC_010516


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  589 bits (2224),  Expect = 3e-169, Method: Compositional matrix adjust.
 Identities = 384/847 (46%), Positives = 543/847 (65%), Gaps = 59/847 (6%)

Query  6    TKIDEKWQKKWEENSLYKFNNKNLDKKLYVLEMFSYPSGSKLHAGHWFNYGPVDSWARFK  65
            T I+ KWQ  W +N  +K        K+Y L+MF+YPSG+ LH GH   Y + D  +RFK
Sbjct  7    TAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSRFK  66

Query  66   RMQGYNVFQPMGFDAFGLPAENYAIKTGIHPKDSTFKNIETMETQLKAMGAMFNWENEVI  125
            R QG NV++PMG DAFGLPAE+YA+ TG +P + T  NI     Q++A+G  ++W+ EV 
Sbjct  67   RAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDREVN  126

Query  126  TCSPDYYKWTQWLFLKLYEKGLAYKKKAPVNWCPSCNTVLANEQVL-DGKCERCDSNVDK  184
            T  P+YYKWTQW+F KLYEKGLAY    PVNW     T +ANE+VL DG  ER +  V +
Sbjct  127  TTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVR  186

Query  185  KNLEQWFLKITDYAdellekldeldWPEKTKAMQKHWIGKSVGAEVTFNVADSDLSFNVF  244
            K + QW LKIT YA+ LLE L+E+DWPE  K MQ++WIGKS GA+VTF+V D+D  F VF
Sbjct  187  KPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVF  246

Query  245  TTRVDTLFGVTYVVLAPENDLVDKLTTPENKAEVESYKTQAKNQSDIERQSITREKTGVF  304
            TTR DTLFG TY VLAPE+ LVD +TT+++   V  YK QA  +SD+ R  +++EKTGV 
Sbjct  247  TTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVW  306

Query  305  SGSYAINPINGKEVPIWIGDYVLNTYGTGCVMAVPAHDERDFAFATKYNLPIERVIEGG-  363
            +GSYAINP+NGKE+P+WI+DYVL +YGTG +MAVPAHDERD  FA ++NL I  V+EGG 
Sbjct  307  TGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGN  366

Query  364  -DSLPYTEYGKMVNSGEFDGLFGNKAKEAVISKLESMNLGRKKINYRLRDWLVSRQRYWG  422
             +  ++TE G  +NS+ +DGL    A   ++  LE+  +G  ++ YRLRDWL SRQRYWG
Sbjct  367  VEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWG  426

Query  423  APIPIIYCEKCGTVEVPIEQLPVELPYNVEFSPDGK--SPLGKCDDFINTTCPKCGGPAK  480
             PIPII  E   +  VP  +LP+ LP   ++ P G   SPL++  D ++ T    G  ++
Sbjct  427  EPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED-GVKGR  485

Query  481  READTLDTFVCSSWYYLRYPDNNNEKDAFNPELINKMLPVDKYVGGPEHACMHLLYARFI  540
            RE++T+     SSWYYLRY D +N     + EL+++ LPVD YVGG+EHA +HLLYARF 
Sbjct  486  RETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFW  545

Query  541  TKALRDMGYLNFDEPFLSLTHQGLILGP----------------------------DGL-  571
             K L D+G +   EPF  L +QG+ILG                             + L 
Sbjct  546  HKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEELE  605

Query  572  ----KMSKSKGNTISPDDYIKEFGADVFRMYLMFGFDYTEGGAWSDDAIKSIGKFVDRVE  627
                KMSKS  N ++PDD + ++GAD +R+Y MF      + AWS++++ +  KF+DRV 
Sbjct  606  QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVY  665

Query  628  RILENAREEIKNSKDNKSTMDKDEKELNYVRHHSIKSITEDIDKMQFNTSIARLMEFTNA  687
            R++             K   + +   L+ V ++++K++TE++D+M+FNT+IA+LM F NA
Sbjct  666  RLI-----------TTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNA  714

Query  688  LSKYLGSDTLRNASFLRESIIDFITLLAPFAPHFAEEQWE-LIGINSSIFNEKWPEFDPK  746
             +K        +  ++ +   +F+ L+APFAPH++EE W+ L +   SI    WP +D  
Sbjct  715  ANK--------EDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDES  766

Query  747  ALIKDEVEIAVQVNGKIRAKINISTSSSEDEIKESALNNDDIKNSIGDKEIKKVIVIKNR  806
             L+ ++VEI VQ++GK++AK+ ++   S +E++E AL N+ ++  I++K+I KVI + N+
Sbjct  767  KLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNK  826

Query  807  LVNIVAK  813
            LVNIV K
Sbjct  827  LVNIVIK  833

775) leuS in NC_011978


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  589 bits (2223),  Expect = 4e-169, Method: Compositional matrix adjust.
 Identities = 379/860 (45%), Positives = 544/860 (64%), Gaps = 70/860 (8%)

Query  19   YRPQEIEEKWQKVWEEKGVFHTPQRSEKPKYYALVMFPYPSGT-LHVGHVKNYVIGDIVA  77
            Y    IE KWQ  W ++  F T   + KPK+YAL MFPYPSG+ LHVGH   Y   DI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  78   RYKRMRGYNVLHPFGYDAFGLPAENAAIEKGIHPEEWTRKNISIIRKQVKRLGISYDWNR  137
            R+KR +G NVLHP G DAFGLPAE+ A++ G +P E T  NI+ +++Q++ LG+SYDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  138  EIATCDEEYYKWTQWIFLQLYKNGLAYKKKAAVNWCPKCKTVLANEQV-KDGKCERCGTS  196
            E+ T D +YYKWTQWIF +LY +GLAY    +VNW     T +ANE+V  DG  ER G +
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  197  VTIKHLEQWFFKITDYAERLLNDLEKLTGWPEHVKTMQRNWIGKSTGAEIEFPVEGSDTK  256
            V  K + QW +KIT YAERLL+DLE + +WPE +K MQRNWIGKSTGA++ F V ++D  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  257  IRVFTTRPDTLWGVTFMALAPESPLVEELVPDDRKEDLQAFLERVKQQDRFKRTSVEAEK  316
            + VFTTRPDTL G T+  LAPE +LV+ +   D+ E +  +  +   +  + RT +  EK
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEK  302

Query  317  EGFFLGRYAVNPVNGERVPIYVANYILMEYGTGAIMGVPAHDQRDFAFARKYGIPIKVVI  376
             G   G YA+NPVNG  +P+ +A+Y+L  YGTGAIM+VPAHD+RD  FA+++ + I  V+
Sbjct  303  TGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL  362

Query  377  KPVDGELDPDKMEEAYEGEGIMVNSGPFTGTPSKEGIEKVINWLEEKGIGKRSVQYKLRD  436
               + E      E A+  +G+ +NS+ + G     +I K+++WLE  G+G+ +V Y+LRD
Sbjct  363  EGGNVE------EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  437  WLISRQRYWGAPIPIIYCEKCGTVPVPEEDLPVRLP--KDVEFLPTGQSPLSFHEGFKKT  494
            WL+SRQRYWG PIPII  E   + +VPE +LP+ LP  KD+    TG+SPL+   +    
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  495  KCPICGGEAQRETDTMDTFVDSSWYFLRYVNPHLDDKPFEPDDVNYWLPVDQYIGGVEHA  554
                 G  ++RET+TM    +SSWY+LRY++PH  +K  + + ++ WLPVD Y+GG EHA
Sbjct  477  TRE-DGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  555  ILHLLYSRFITKVLHDLGYLNFDEPFTNLFTQGMI----YKDG-----------------  593
            +LHLLY+RF  KVL DLG +   EPF +LF QGMI    Y+D+                 
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSF  595

Query  594  -------------AKMSKSKGNVVSPDDMIEKYGADTLRMYILFMAPPEKDAEWSDAGIE  640
                         AKMSKS  NVV+PDD++E+YGADTLR+Y +FM+P +    WS+ G+E
Sbjct  596  FHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLE  655

Query  641  GVHRFIRRLWNTFYTILPHVKEETVEGLSLTTPVEKELRRKLHSIIKKITEDIEGGFKFN  700
            G ++F+ R+    Y ++   KE T E  +        L +  +  +K +TE+++   KFN
Sbjct  656  GSRKFLDRV----YRLIT-TKEITEENSG-------ALDKVYNETVKAVTEQVD-QMKFN  702

Query  701  TAISGLMELINHLNQYLSGVPEDQWNRKLLREIAENLTLVLSPFAPHLAEEFWHELGQEG  760
            TAI+ LM ++N  N+          + KL+ + A  +  +++PFAPHL+EE+W+ L   G
Sbjct  703  TAIAQLMVFVNAANK----------EDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASG  752

Query  761  LVVQ-QSWPSYDPKALEVEEMEIAIQINGKVRDKILVPVDISEEELKKMVMERERVKEYI  819
              +   +WPSYD   L  +++EI +QI+GKV+ K++V+ D+S EEL+ + +  E+V+  I
Sbjct  753  ESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEI  812

Query  820  DGKTVKKFIYVKGRIVNIVI  839
             GK + K I V  ++VNIVI
Sbjct  813  AGKDIIKVIAVPNKLVNIVI  832

776) Cyast_1429 in NC_019778


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  588 bits (2222),  Expect = 4e-169, Method: Compositional matrix adjust.
 Identities = 368/853 (44%), Positives = 558/853 (66%), Gaps = 41/853 (4%)

Query  5    YQASDIENKWQQQWTEKELYKTEENSDKPKFYALSMFPYPSGK-LHMGHVRNYVITDVIA  63
            Y+ + IE KWQ  W++++ +KT  ++ KPKFYAL MFPYPSG  LH+GH   Y  TD+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RFQRMNGHRVLHPMGWDAFGLPAENAAIDRGIPPATWTYQNIDQMRSQLKQLGLSIDWDR  123
            RF+R +GH VLHPMGWDAFGLPAE+ A+D G  PA  T +NI + + Q++ LG+S DWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVATCSPEYYKWTQWLFLQFYQAGLAYQKEAAVNWDPIDQTVLANEQVDGDGYSWRSGAK  183
            EV T  P+YYKWTQW+F ++Y+ GLAY+ E +VNW     T +ANE+V  DG S R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  184  VERKLLRQWFFKITDYAEQLLQDLCQLDGWPERVKTMQENWIGKSVGAYLEFPVIDKDEK  243
            V RK +RQW +KIT YAE+LL+DL ++D WPE +K MQ NWIGKS GA + F V D D  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  244  IAVFTTRPDTVYGVTYVVLAPEHPLTPLVTTPDRKKAVEDFIKEVSAESEIDRTADDKPK  303
            ++VFTTRPDT++G TY VLAPEH+L   +TT+D+  AV D+ ++ S  S++ RT   K K
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEK  302

Query  304  KGVLTGGKAINPFTGEEIPILIANYVLYEYGTGAVMGVPAHDVRDFKFAKENNLPIKVVI  363
             GV TG+ AINP  G E+P+ IA+YVL  YGTGA+M+VPAHD RD  FAK+ NL I  V+
Sbjct  303  TGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL  362

Query  364  IPDDSDNEVPELQEAYTEPGTMVNSGSFTGMDSTKGKNAVIQFAENQGYGKKRIQYRLRD  423
              ++ +      + A+TE G  +NS+ + G+D + +   +++  E +G G+  + YRLRD
Sbjct  363  EGGNVE------EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  424  WLISRQRYWGCPIPVVHCPNCGTVPVPDQDLPVKLP--DQVEFSGRGPSPLAKMEDWVNV  481
            WL+SRQRYWG PIP++H  +  + +VP+ +LP+ LP   ++  SG G SPLA++ DW++V
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  482  PCPSCGTPAKRETDTMDTFIDSSWYFLRYTDANNENEPFSLDRVNNWMGVDQYVGGIEHA  541
                 G  ++RET+TM    +SSWY+LRY D++N +     + +++W+ VD YVGG EHA
Sbjct  477  TRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  542  ILHLLYSRFFTKVVRDRGLVNVDEPFKRLLTQGMVQGITYKNPVTGKYILPenieereet  601
            +LHLLY+RF  KV+ D G+V   EPF++L+ QGM+ G +Y+++  +             T
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGA----------LVAT  585

Query  602  naeGKTETVYYDKATGDRLSVFYEKMSKSKYNGVDPQVVLSKYGADTARMFILFKAPPEK  661
            +   K +  +++  TG+ L     KMSKS  N V+P+ V+ +YGADT R++ +F +P + 
Sbjct  586  DKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  662  DLEWDDADVEGQYRFLNRVWTLVNEFIDNSQSAENKTIDKTKLSKTEKDLRRAIHTAIKE  721
             + W + ++EG  +FL+RV  L+                K         L +  + ++K 
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLIT--------------TKEITEENSGALDKVYNETVKA  691

Query  722  ISEDLNGDYQFNTAVSELMKLNNALRDSKDKNSPVYREGIETLILLLAPFAPHIGEELWQ  781
            ++E+++ + +FNTA+++LM     + ++ +K+  ++ +    ++ L+APFAPH+GEELWQ
Sbjct  692  VTEQVD-QMKFNTAIAQLM----VFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  782  -LLGNSESVHLQPWLTVDEEALTVDEITLVIQIMGKTRGTISVPAGATKDELQQFAQESE  840
             L +++ES+   PW + DE  L  +++ +V+QI GK ++ + V+ + +++ELQ+ A  +E
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  841  VAQKYITGKEIKK  853
              Q  I+GK+I K
Sbjct  807  KVQAEIAGKDIIK  819

777) UCYN_00260 in NC_013771


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  588 bits (2222),  Expect = 4e-169, Method: Compositional matrix adjust.
 Identities = 372/856 (44%), Positives = 565/856 (67%), Gaps = 33/856 (3%)

Query  15   YKTAEIENKWQQEWLRQGLDKTPENSEKQKFYALSMFPYPSG-NLHMGHVRNYVITDVIA  73
            Y  + IE KWQ  W  +   KT  ++ K KFYAL MFPYPSG  LH+GH   Y  TD+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  74   RFKRLQGYSVLHPMGWDAFGLPAENAAIDRGISPEEWTKKNIAKMRQQLQSLGLSIDWER  133
            RFKR QG +VLHPMGWDAFGLPAE+ A+D G  P E T  NIA+ ++Q+++LG+S DW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  134  EITTCSPSYYKWTQWLFLQFYKVGLAYQKEATVNWDPVDQTVLANEQVDTEGYSWRSGAK  193
            E+ T  P+YYKWTQW+F ++Y  GLAY+ E  VNW     T +ANE+V  +G S R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  194  VEKKLLCQWFLKITDYAEYLLNDLNTLKGWPDSVKLMQKNWIGKSLGAHIQFPVKDTKKS  253
            V +K + QW LKIT YAE LL+DL+ + +WP+S+K MQ+NWIGKS GA++ F VKDT K 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  254  ISIFTTRPDTIYGVTYLVLAPDHPLVMTIAKPEHKEKIRKFTQEVANESEIERTADDKPL  313
            +++FTTRPDT++G TY VLAP+H+LV +I+ +++ E +  + ++ +  S++ RT   K  
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEK  302

Query  314  KGIFIGAEVINPFSGDEIPVFIASYVLLDYGTGAVMGVPAHDNRDFKFATEQQLPVKVVV  373
             G+  G+  INP +G E+PV IA YVL  YGTGA+M+VPAHD+RD  FA  +Q+ + ++ 
Sbjct  303  TGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFA--KQFNLDIIP  360

Query  374  IPKNSNSRETTQLSLKEAYIESGTIINSEQFNGMYSEDAKAAVIEYAKKHSIGEAKVQYR  433
            +   +N  E+       A+ E G  INS+ ++G+    A A ++E    +++G+ +V YR
Sbjct  361  VLEGGNVEEA-------AFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYR  413

Query  434  IRDWLISRQRYWGCPIPIIHCSDCGTVAIPDSQLPLELP--KNVEFTGRGSSPLEGLKEW  491
            +RDWL+SRQRYWG PIPIIH  D  + A+P+S+LPL LP  K++  +G G SPL  + +W
Sbjct  414  LRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDW  473

Query  492  VNVPCPNCGKLAKRETDTMDTFIDSSWYYLRYTDSKNSQEIFNPDKAKYWAPVDQYVGGV  551
            ++V   +  K ++RET+TM    +SSWYYLRY D+ N++ + + +  K W PVD YVGG 
Sbjct  474  LEVTREDGVK-GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGA  532

Query  552  EHAILHLLYSRFLTKFLKNQKLIDINEPFKNLLTQGMVQGITYKNLKTGKYIPCDQVNSA  611
            EHA+LHLLY+RF  K L +  ++  +EPF++L+ QGM+ G +Y++ + G  ++ D+V+  
Sbjct  533  EHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSR-GALVATDKVEKR  591

Query  612  KPT--DPVTGDDLEAFYEKMSKSKYNGVDPQEVLEKYGADTARMFILFKAPPEKDLEWSS  669
              +  +  TG++LE    KMSKS  N V+P++V+E+YGADT R++ +F +P +  + WS 
Sbjct  592  DGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSE  651

Query  670  SDVEGQFRFLNRVWRLVHLYIQNKNNKTQSKTLTKNEKDLKRSIHTIIKEVSQDLEENYQ  729
             ++EG  +FL+RV RL+          T       N   L +  +  +K V++++++  +
Sbjct  652  EGLEGSRKFLDRVYRLI----------TTKEITEENSGALDKVYNETVKAVTEQVDQM-K  700

Query  730  FNTAIAELMKLSNVLNDFKDINSSVYQEGIVALLTLLSPFAPHISEELWHSL-GYKESIH  788
            FNTAIA+LM    V+ +  + +  ++ +   +++ L++PFAPH++EELW++L +  ESI 
Sbjct  701  FNTAIAQLM----VFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESIS  756

Query  789  LQKWPSVDNQALVLDEVTIVIQAMGKTKGTIQAPANSSNEELEKLARNSEIGKRLLNKKE  848
               WPS D+  LV ++V IV+Q  GK K+ +  + + S EEL+ +A  +E  +  +  K+
Sbjct  757  YVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKD  816

Query  849  IKKTIVVPQKLVNFVL  864
            I K I VP+KLVN+V+
Sbjct  817  IIKVIAVPNKLVNIVI  832

778) leuS in NC_007516


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  588 bits (2222),  Expect = 4e-169, Method: Compositional matrix adjust.
 Identities = 372/857 (44%), Positives = 567/857 (67%), Gaps = 34/857 (3%)

Query  23   YDPTALEQRWQESWKADGVDTTEVGGEKPGFFALSMFPYPSGS-LHMGHVRNYVITDVIA  81
            YD TA+E +WQ  W  +    T  ++ KP F+AL MFPYPSG+ LH+GH   Y  TD+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  82   RVQRMLGHAVLHPMGWDAFGLPAENAAIERNVDPGEWTDRNIDQMRAQLDRLGLSIDWSR  141
            R +R  GH VLHPMGWDAFGLPAE+ A++   DP+E T  NI + + Q++ LG+S DW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  142  EQATCHSDYYRWTQWLFLELLEGGLAYRKNATVNWDPVDQTVLANEQVDGDGRSWRSGAL  201
            E  T +++YY+WTQW+F  L E GLAY  +  VNW     T +ANE+V  DG S R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  202  VEQRQLNQWFLRITDYAEPLLNDLDALKGWPERVRTMQANWIGRSEGAEISFNVEGAQNQ  261
            V ++ + QW L+IT YAE LL+DL+ + +WPE ++ MQ NWIG+S GA+++F+V +++++
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  262  TITVFTTRPDTLAGASYVVLAPENELVDSLSSEEQKDTVEAFRKEVARLSTIERTCDDRP  321
             +TVFTTRPDTL GA+Y VLAPE+ LVD++++ +Q ++V  ++++ +  S + RT   + 
Sbjct  243  -FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKE  301

Query  322  KRGVPIGSHVINPLTGVVLPVWIADYVLAEYGTGAVMGVPAHDQRDIAFAQSNGLPIQQV  381
            K GV  GS  INP+ G  +PVWIADYVLA YGTGA+M+VPAHD+RD  FA+   L I  V
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  382  IDaegaaeaiaagqaWTDAGTLVNSGSFDGTASSEAKGAITGHGAEQGWARSKVTYRLRD  441
            +++    EA       T+ G  +NS+ +DG   + A + +      +G +  +VTYRLRD
Sbjct  362  LEGGNVEEAAF-----TEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  442  WLISRQRYWGCPIPVIHCDNCGAVPVPREDLPVELP--RGIDLSGKGGSPLSQQSDWVNV  499
            WL+SRQRYWG PIP+IH ++  + +VP  +LP+ LP  ++I  SG G SPL++ +DW++V
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  500  ACPRCGKPAKRETDTMDTFMCSSWYFLRFADPHNTEKPFSKEAVNRWLPVKQYVGGIEHA  559
            +     K ++RET+TM     SSWY+LR+ DPHNTEK    E +++WLPV  YVGG EHA
Sbjct  477  TREDGVK-GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  560  ILHLLYARFFTKALKDRGLIDINEPFERLLTQGMVQGVTYRNATTGKYIAPADVADAEDP  619
            +LHLLYARF  K L D G++  +EPF++L+ QGM+ G +YR+ + G  +A   V   +++
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRD-SRGALVATDKVEKRDGS  594

Query  620  -RDPNTGDKLEVLFEKMSKSKYNGVDPAAVIDRYGADTARMFILFKAPPEKDLEWDDADV  678
              + +TG+ LE    KMSKS  N V+P  V+++YGADT R++ +F +P +  + W + ++
Sbjct  595  FFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGL  654

Query  679  EGQFRFLQRLWRLVEAGSARIDSLEPMQRPADLSDADSDVRRALHLAIEAVSEDLSDEIQ  738
            EG  +FL+R+ RL+ +                  +  + + +  + ++ AV+E++ D+++
Sbjct  655  EGSRKFLDRVYRLITTKEIT-------------EENSGALDKVYNETVKAVTEQV-DQMK  700

Query  739  LNTAISELMKLSNAISSTGIDALSAPVLQEALSGLVRLLAPFAPHLAEEFWNRLGGSG-S  797
            +NTAI++LM + NA +          ++ +   G+V+L+APFAPHL+EE+W+ L +SG S
Sbjct  701  FNTAIAQLMVFVNAANK------EDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGES  754

Query  798  VHRQSWPVLDPTALVQDSVEVVIQVKGKVRGKLQVPASAGKEELERLALASDVAEKWLEG  857
            +   +WP  D + LV++ VE+V+Q+KGKV++KL V+   ++EEL+ +ALA++  +  + G
Sbjct  755  ISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAG  814

Query  858  AAPRRVIVVPGKLVNLV  874
                +VI VP KLVN+V
Sbjct  815  KDIIKVIAVPNKLVNIV  831

779) leuS in NC_011297


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  588 bits (2221),  Expect = 5e-169, Method: Compositional matrix adjust.
 Identities = 382/847 (46%), Positives = 545/847 (65%), Gaps = 52/847 (6%)

Query  15   MKRYNPQEIEPKWQKKWNEDKLYHVTERSDKPKYYTLVMFPYPSG-DLHMGHMRNYTIGD  73
            M  Y+   IEPKWQ  W ++  +     + KPK+Y+L MFPYPSG +LH+GH   YT  D
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  74   VVARYYTMKGYNVLNPMGWDAFGQPAENAAIKHKVHPKEWTYKNIARMKEQLFKMGVVYD  133
            +++R+   +G NVL+PMGWDAFG PAE+ A+    +P E T  NIA  K Q+  +G  YD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  134  WDREVTACAPDYYKWTQWIFLKLYERGLAYRKKAPANWCPTCKTVLANEEVI-DGKCWRC  192
            WDREV +  P+YYKWTQWIF KLYE+GLAY    P NW     T +ANEEV+ DG   R 
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  193  KSPVERREFEQWFFKITEYAEDLLKDLDTLEHWPEKVKLMQKNWIGKSEGLEFYFEVEGS  252
              PV R+   QW +KIT YAE LL DL+ ++ WPE +K MQ+NWIGKS G +  F V ++
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDT  239

Query  253  DEKIYVYTTRPDTIYGVTFVVLAPEHPLVEKITKPEYLNEVMEYVRQAKNKSELERLTSE  312
            D  + V+TTRPDT++G T+ VLAPEH+LV+ IT ++  + V +Y RQA  KS+L R    
Sbjct  240  DKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA  299

Query  313  KEKTGVFTGSYAIHPLTKQPVPIYVADYVLATYGTGAIMAVPAHDSRDYDFAVKFNLPII  372
            KEKTGV TGSYAI+P+  + +P+ +ADYVLA+YGTGAIMAVPAHD RD +FA +FNL II
Sbjct  300  KEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDII  359

Query  373  PVITPDPDKLPELPYEEEGVMINSGEYNGMKSSDFWKLIVEKFESLGIGKKKVQYRLRDW  432
            PV+  + +++ E ++ E+G+ INS+  +G+  +     +VE +E+ G+G+ +V YRLRDW
Sbjct  360  PVL--EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDW  417

Query  433  LISRQRYWGAPIPIIYCPNCGIVPVPYEDLPVELPELSDFEPTGTGESPLAKVPEFVNTK  492
            L+SRQRYWG PIPII   +    +VP  +LP+ LP   D+ P+GTGESPLA+V + ++  
Sbjct  418  LFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT  477

Query  493  CPKCGAPARRETDTLATFVDSSWYYFRYTDPHNDKEPFSREKAEYWMPVDQYTGGIEHAV  552
                G  +RRET+T++   +SSWYY+RY DPHN       E    W+PVD Y GG EHAV
Sbjct  478  RED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  553  LHLLYSRFITKVLYDAGYSPVREPFKRLFTQGMV----YKDGQI----------------  592
            LHLLY+RF  KVLYD G  P +EPF++LF QGM+    Y+D++                 
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFF  596

Query  593  --------------MSKSLGNIVSVDYMVENYGADTARLFILFVAPPEVDIEWSDEGVEG  638
                          MSKSL N+V+ D +VE+YGADT R++ +F++P +  I WS+EG+EG
Sbjct  597  HVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEG  656

Query  639  ANRFLNRFWRLVLDDAEVEPKVDEEQEKLIRRKLHKTIKKVTEDIENFKFNTAIAAIMEL  698
            + +FL+R  RL+         + EE+   + +  + T+K VTE++++ KFNTAIA +M +
Sbjct  657  SRKFLDRVYRLI-----TTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVF  711

Query  699  TNLLFDHKRNFGRTPAFEEAIKTSILLLSPFVPHITEELWSEL-GNEYSVHMQKWPSYDP  757
             N    + + F+      +  K  + L++PF PH+ EELW  L ++  S+    WPSYD 
Sbjct  712  VNAANKEDKLFS------DYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDE  765

Query  758  EMIKEEIVTVVIQINGRVRDRIDVNADATQEEVLRLALDRENVKKYLDNKEIKKVVYVPG  817
              + E+ V +V+QI+G+V+ ++ V  D ++EE+  +AL  E+V+  +  K+I KV+ VP 
Sbjct  766  SKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPN  825

Query  818  KILSLYV  824
            K++++ +
Sbjct  826  KLVNIVI  832

780) leuS in NC_009697


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  588 bits (2220),  Expect = 6e-169, Method: Compositional matrix adjust.
 Identities = 386/847 (46%), Positives = 542/847 (64%), Gaps = 59/847 (6%)

Query  6    TKIDEKWQKKWEENSLYKFNNKNLDKKLYVLEMFSYPSGSKLHAGHWFNYGPVDSWARFK  65
            T I+ KWQ  W +N  +K        K+Y L+MF+YPSG+ LH GH   Y + D  +RFK
Sbjct  7    TAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSRFK  66

Query  66   RMQGYNVFQPMGFDAFGLPAENYAIKTGIHPKDSTFKNIETMETQLKAMGAMFNWENEVI  125
            R QG NV++PMG DAFGLPAE+YA+ TG +P + T  NI     Q++A+G  ++W+ EV 
Sbjct  67   RAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDREVN  126

Query  126  TCSPDYYKWTQWLFLKLYEKGLAYKKKAPVNWCPSCNTVLANEQVL-DGKCERCDSNVDK  184
            T  P+YYKWTQW+F KLYEKGLAY    PVNW     T +ANE+VL DG  ER +  V +
Sbjct  127  TTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVR  186

Query  185  KNLEQWFLKITDYAdellekldeldWPEKTKAMQKHWIGKSVGAEVTFNVADSDLSFNVF  244
            K + QW LKIT YA+ LLE L+E+DWPE  K MQ++WIGKS GA+VTF+V D+D  F VF
Sbjct  187  KPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVF  246

Query  245  TTRVDTLFGVTYVVLAPENDLVDKLTTPENKAEVESYKTQAKNQSDIERQSITREKTGVF  304
            TTR DTLFG TY VLAPE+ LVD +TT+++   V  YK QA  +SD+ R  +++EKTGV 
Sbjct  247  TTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVW  306

Query  305  SGSYAINPINGKKVPIWIGDYVLNTYGTGCVMAVPAHDERDFAFATKYNLPIERVIEGG-  363
            +GSYAINP+NGK +P+WI+DYVL +YGTG +MAVPAHDERD  FA ++NL I  V+EGG 
Sbjct  307  TGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGN  366

Query  364  -DSLPYTEYGGMVNSGEFDGLLGNEAKEAVISKLESMNLGRKKINYRLRDWLVSRQRYWG  422
             +  ++TE G  +NS+ +DGL    A   ++  LE+  +G  ++ YRLRDWL SRQRYWG
Sbjct  367  VEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWG  426

Query  423  APIPIIYCEKCGTVEVPIEQLPVELPYNVEFSPDGK--SPLGKCDDFINTTCPKCGGPAK  480
             PIPII  E   +  VP  +LP+ LP   ++ P G   SPL++  D ++ T    G  ++
Sbjct  427  EPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED-GVKGR  485

Query  481  READTLDTFVCSSWYYLRYPDNNNEKDAFNPELINKMLPVDKYVGGPEHACMHLLYARFI  540
            RE++T+     SSWYYLRY D +N     + EL+++ LPVD YVGG+EHA +HLLYARF 
Sbjct  486  RETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFW  545

Query  541  TKALRDMGYLNFDEPFLSLTHQGLILGP----------------------------DGL-  571
             K L D+G +   EPF  L +QG+ILG                             + L 
Sbjct  546  HKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEELE  605

Query  572  ----KMSKSKGNTISPDDYIKEFGADVFRMYLMFGFDYTEGGAWSDDAIKSIGKFVDRVE  627
                KMSKS  N ++PDD + ++GAD +R+Y MF      + AWS++++ +  KF+DRV 
Sbjct  606  QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVY  665

Query  628  RILENAREEIKNSKDNKSTMDKDEKELNYVRHHSIKSITEDIDKMQFNTSIARLMEFTNA  687
            R++             K   + +   L+ V ++++K++TE++D+M+FNT+IA+LM F NA
Sbjct  666  RLI-----------TTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNA  714

Query  688  LSKYLGIDAIKNALFLRESIIDFITLLAPFAPHFAEEQWK-LIGINSSIFNEKWPEFDPK  746
             +K        + LF  +   +F+ L+APFAPH++EE W+ L +   SI    WP +D  
Sbjct  715  ANK-------EDKLF-SDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDES  766

Query  747  ALIKDEVEIAVQVNGKIRAKINISTSSSEDEIKESALNNEDIKNSIGDKEIKKVIVIKNR  806
             L+ ++VEI VQ++GK++AK+ ++   S +E++E AL NE ++  I++K+I KVI + N+
Sbjct  767  KLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNK  826

Query  807  LVNIVAK  813
            LVNIV K
Sbjct  827  LVNIVIK  833

781) leuS in NC_009495


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  588 bits (2220),  Expect = 6e-169, Method: Compositional matrix adjust.
 Identities = 386/847 (46%), Positives = 542/847 (64%), Gaps = 59/847 (6%)

Query  6    TKIDEKWQKKWEENSLYKFNNKNLDKKLYVLEMFSYPSGSKLHAGHWFNYGPVDSWARFK  65
            T I+ KWQ  W +N  +K        K+Y L+MF+YPSG+ LH GH   Y + D  +RFK
Sbjct  7    TAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSRFK  66

Query  66   RMQGYNVFQPMGFDAFGLPAENYAIKTGIHPKDSTFKNIETMETQLKAMGAMFNWENEVI  125
            R QG NV++PMG DAFGLPAE+YA+ TG +P + T  NI     Q++A+G  ++W+ EV 
Sbjct  67   RAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDREVN  126

Query  126  TCSPDYYKWTQWLFLKLYEKGLAYKKKAPVNWCPSCNTVLANEQVL-DGKCERCDSNVDK  184
            T  P+YYKWTQW+F KLYEKGLAY    PVNW     T +ANE+VL DG  ER +  V +
Sbjct  127  TTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVR  186

Query  185  KNLEQWFLKITDYAdellekldeldWPEKTKAMQKHWIGKSVGAEVTFNVADSDLSFNVF  244
            K + QW LKIT YA+ LLE L+E+DWPE  K MQ++WIGKS GA+VTF+V D+D  F VF
Sbjct  187  KPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVF  246

Query  245  TTRVDTLFGVTYVVLAPENDLVDKLTTPENKAEVESYKTQAKNQSDIERQSITREKTGVF  304
            TTR DTLFG TY VLAPE+ LVD +TT+++   V  YK QA  +SD+ R  +++EKTGV 
Sbjct  247  TTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVW  306

Query  305  SGSYAINPINGKKVPIWIGDYVLNTYGTGCVMAVPAHDERDFAFATKYNLPIERVIEGG-  363
            +GSYAINP+NGK +P+WI+DYVL +YGTG +MAVPAHDERD  FA ++NL I  V+EGG 
Sbjct  307  TGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGN  366

Query  364  -DSLPYTEYGGMVNSGEFDGLLGNEAKEAVISKLESMNLGRKKINYRLRDWLVSRQRYWG  422
             +  ++TE G  +NS+ +DGL    A   ++  LE+  +G  ++ YRLRDWL SRQRYWG
Sbjct  367  VEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWG  426

Query  423  APIPIIYCEKCGTVEVPIEQLPVELPYNVEFSPDGK--SPLGKCDDFINTTCPKCGGPAK  480
             PIPII  E   +  VP  +LP+ LP   ++ P G   SPL++  D ++ T    G  ++
Sbjct  427  EPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED-GVKGR  485

Query  481  READTLDTFVCSSWYYLRYPDNNNEKDAFNPELINKMLPVDKYVGGPEHACMHLLYARFI  540
            RE++T+     SSWYYLRY D +N     + EL+++ LPVD YVGG+EHA +HLLYARF 
Sbjct  486  RETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFW  545

Query  541  TKALRDMGYLNFDEPFLSLTHQGLILGP----------------------------DGL-  571
             K L D+G +   EPF  L +QG+ILG                             + L 
Sbjct  546  HKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEELE  605

Query  572  ----KMSKSKGNTISPDDYIKEFGADVFRMYLMFGFDYTEGGAWSDDAIKSIGKFVDRVE  627
                KMSKS  N ++PDD + ++GAD +R+Y MF      + AWS++++ +  KF+DRV 
Sbjct  606  QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVY  665

Query  628  RILENAREEIKNSKDNKSTMDKDEKELNYVRHHSIKSITEDIDKMQFNTSIARLMEFTNA  687
            R++             K   + +   L+ V ++++K++TE++D+M+FNT+IA+LM F NA
Sbjct  666  RLI-----------TTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNA  714

Query  688  LSKYLGIDAIKNALFLRESIIDFITLLAPFAPHFAEEQWK-LIGINSSIFNEKWPEFDPK  746
             +K        + LF  +   +F+ L+APFAPH++EE W+ L +   SI    WP +D  
Sbjct  715  ANK-------EDKLF-SDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDES  766

Query  747  ALIKDEVEIAVQVNGKIRAKINISTSSSEDEIKESALNNEDIKNSIGDKEIKKVIVIKNR  806
             L+ ++VEI VQ++GK++AK+ ++   S +E++E AL NE ++  I++K+I KVI + N+
Sbjct  767  KLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNK  826

Query  807  LVNIVAK  813
            LVNIV K
Sbjct  827  LVNIVIK  833

782) leuS in NC_009698


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  588 bits (2220),  Expect = 6e-169, Method: Compositional matrix adjust.
 Identities = 386/847 (46%), Positives = 542/847 (64%), Gaps = 59/847 (6%)

Query  6    TKIDEKWQKKWEENSLYKFNNKNLDKKLYVLEMFSYPSGSKLHAGHWFNYGPVDSWARFK  65
            T I+ KWQ  W +N  +K        K+Y L+MF+YPSG+ LH GH   Y + D  +RFK
Sbjct  7    TAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSRFK  66

Query  66   RMQGYNVFQPMGFDAFGLPAENYAIKTGIHPKDSTFKNIETMETQLKAMGAMFNWENEVI  125
            R QG NV++PMG DAFGLPAE+YA+ TG +P + T  NI     Q++A+G  ++W+ EV 
Sbjct  67   RAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDREVN  126

Query  126  TCSPDYYKWTQWLFLKLYEKGLAYKKKAPVNWCPSCNTVLANEQVL-DGKCERCDSNVDK  184
            T  P+YYKWTQW+F KLYEKGLAY    PVNW     T +ANE+VL DG  ER +  V +
Sbjct  127  TTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVR  186

Query  185  KNLEQWFLKITDYAdellekldeldWPEKTKAMQKHWIGKSVGAEVTFNVADSDLSFNVF  244
            K + QW LKIT YA+ LLE L+E+DWPE  K MQ++WIGKS GA+VTF+V D+D  F VF
Sbjct  187  KPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVF  246

Query  245  TTRVDTLFGVTYVVLAPENDLVDKLTTPENKAEVESYKTQAKNQSDIERQSITREKTGVF  304
            TTR DTLFG TY VLAPE+ LVD +TT+++   V  YK QA  +SD+ R  +++EKTGV 
Sbjct  247  TTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVW  306

Query  305  SGSYAINPINGKKVPIWIGDYVLNTYGTGCVMAVPAHDERDFAFATKYNLPIERVIEGG-  363
            +GSYAINP+NGK +P+WI+DYVL +YGTG +MAVPAHDERD  FA ++NL I  V+EGG 
Sbjct  307  TGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGN  366

Query  364  -DSLPYTEYGGMVNSGEFDGLLGNEAKEAVISKLESMNLGRKKINYRLRDWLVSRQRYWG  422
             +  ++TE G  +NS+ +DGL    A   ++  LE+  +G  ++ YRLRDWL SRQRYWG
Sbjct  367  VEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWG  426

Query  423  APIPIIYCEKCGTVEVPIEQLPVELPYNVEFSPDGK--SPLGKCDDFINTTCPKCGGPAK  480
             PIPII  E   +  VP  +LP+ LP   ++ P G   SPL++  D ++ T    G  ++
Sbjct  427  EPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED-GVKGR  485

Query  481  READTLDTFVCSSWYYLRYPDNNNEKDAFNPELINKMLPVDKYVGGPEHACMHLLYARFI  540
            RE++T+     SSWYYLRY D +N     + EL+++ LPVD YVGG+EHA +HLLYARF 
Sbjct  486  RETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFW  545

Query  541  TKALRDMGYLNFDEPFLSLTHQGLILGP----------------------------DGL-  571
             K L D+G +   EPF  L +QG+ILG                             + L 
Sbjct  546  HKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEELE  605

Query  572  ----KMSKSKGNTISPDDYIKEFGADVFRMYLMFGFDYTEGGAWSDDAIKSIGKFVDRVE  627
                KMSKS  N ++PDD + ++GAD +R+Y MF      + AWS++++ +  KF+DRV 
Sbjct  606  QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVY  665

Query  628  RILENAREEIKNSKDNKSTMDKDEKELNYVRHHSIKSITEDIDKMQFNTSIARLMEFTNA  687
            R++             K   + +   L+ V ++++K++TE++D+M+FNT+IA+LM F NA
Sbjct  666  RLI-----------TTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNA  714

Query  688  LSKYLGIDAIKNALFLRESIIDFITLLAPFAPHFAEEQWK-LIGINSSIFNEKWPEFDPK  746
             +K        + LF  +   +F+ L+APFAPH++EE W+ L +   SI    WP +D  
Sbjct  715  ANK-------EDKLF-SDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDES  766

Query  747  ALIKDEVEIAVQVNGKIRAKINISTSSSEDEIKESALNNEDIKNSIGDKEIKKVIVIKNR  806
             L+ ++VEI VQ++GK++AK+ ++   S +E++E AL NE ++  I++K+I KVI + N+
Sbjct  767  KLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNK  826

Query  807  LVNIVAK  813
            LVNIV K
Sbjct  827  LVNIVIK  833

783) H04402_00175 in NC_017299


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  587 bits (2216),  Expect = 1e-168, Method: Compositional matrix adjust.
 Identities = 384/847 (46%), Positives = 545/847 (65%), Gaps = 59/847 (6%)

Query  6    TKIDEKWQKKWEENSLYKFNNDNLDKKLYVLEMFSYPSGSKLHAGHWFNYGPVDSWARFK  65
            T I+ KWQ  W +N  +K   D    K+Y L+MF+YPSG+ LH GH   Y + D  +RFK
Sbjct  7    TAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSRFK  66

Query  66   RMQGYNVFQPMGFDAFGLPAENYAIKTGIHPKDSTFKNIETMETQLKAMGAMFNWENEVI  125
            R QG NV++PMG DAFGLPAE+YA+ TG +P + T  NI     Q++A+G  ++W+ EV 
Sbjct  67   RAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDREVN  126

Query  126  TCSPDYYKWTQWLFLKLYEKGLAYKKKAPVNWCPSCNTVLANEQVL-DGKCERCDSNVDK  184
            T  P+YYKWTQW+F KLYEKGLAY    PVNW     T +ANE+VL DG  ER +  V +
Sbjct  127  TTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVR  186

Query  185  KNLEQWFLKITDYAdellekldeldWPEKTKAMQKHWIGKSVGAEVTFNVADSDLSFNVF  244
            K + QW LKIT YA+ LLE L+E+DWPE  K MQ++WIGKS GA+VTF+V D+D  F VF
Sbjct  187  KPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVF  246

Query  245  TTRVDTLFGVTYVVLAPENDLVDKLTTPENKAEVESYKTQAKNQSDIERQSITREKTGVF  304
            TTR DTLFG TY VLAPE+ LVD +TT+++   V  YK QA  +SD+ R  +++EKTGV 
Sbjct  247  TTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVW  306

Query  305  SGSYAINPINGKKVPIWIGDYVLNTYGTGCVMAVPAHDERDFAFATKYNLPIERVIEGG-  363
            +GSYAINP+NGK +P+WI+DYVL +YGTG +MAVPAHDERD  FA ++NL I  V+EGG 
Sbjct  307  TGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGN  366

Query  364  -DSLPYTEYGKMVNSGEFDGLFGNKAKEAVISKLESMNLGRKKINYRLRDWLVSRQRYWG  422
             +  ++TE G  +NS+ +DGL    A   ++  LE+  +G  ++ YRLRDWL SRQRYWG
Sbjct  367  VEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWG  426

Query  423  APIPIIYCEKCGTVEVPIEQLPVELPYNVEFSPDGK--SPLGKCDDFINTTCPKCGGPAK  480
             PIPII  E   +  VP  +LP+ LP   ++ P G   SPL++  D ++ T    G  ++
Sbjct  427  EPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED-GVKGR  485

Query  481  READTLDTFVCSSWYYLRYPDNNNEKDAFNPELINKMLPVDKYVGGPEHACMHLLYARFI  540
            RE++T+     SSWYYLRY D +N     + EL+++ LPVD YVGG+EHA +HLLYARF 
Sbjct  486  RETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFW  545

Query  541  TKALRDMGYLNFDEPFLSLTHQGLILGP----------------------------DGL-  571
             K L D+G +   EPF  L +QG+ILG                             + L 
Sbjct  546  HKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEELE  605

Query  572  ----KMSKSKGNTISPDDYIKEFGADVFRMYLMFGFDYTEGGAWSDDAIKSIGKFVDRVE  627
                KMSKS  N ++PDD + ++GAD +R+Y MF      + AWS++++ +  KF+DRV 
Sbjct  606  QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVY  665

Query  628  RILENAREEIKNSKDNKFTMDKDEKELNYVRHHSIKSITEDIDKMQFNTSIARLMEFTNA  687
            R++         +K+     + +   L+ V ++++K++TE++D+M+FNT+IA+LM F NA
Sbjct  666  RLI--------TTKE---ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNA  714

Query  688  LSKYLGSDTLRNASFLRESIIDFITLLAPFAPHFAEEQWE-LIGINSSIFNEKWPEFDPK  746
             +K        +  ++ +   +F+ L+APFAPH++EE W+ L +   SI    WP +D  
Sbjct  715  ANK--------EDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDES  766

Query  747  ALIKDEVEIAVQVNGKIRAKINISTSSSEDEIKESALDNDDIKNSIGDKEIKKVIVIKNR  806
             L+ ++VEI VQ++GK++AK+ ++   S +E++E AL N+ ++  I++K+I KVI + N+
Sbjct  767  KLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNK  826

Query  807  LVNIVAK  813
            LVNIV K
Sbjct  827  LVNIVIK  833

784) CBF_0218 in NC_017297


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  587 bits (2217),  Expect = 9e-169, Method: Compositional matrix adjust.
 Identities = 384/847 (46%), Positives = 542/847 (64%), Gaps = 59/847 (6%)

Query  6    TKIDEKWQKKWEENSLYKFNNDNLDKKLYVLEMFSYPSGSKLHAGHWFNYGPVDSWARFK  65
            T I+ KWQ  W +N  +K   D    K+Y L+MF+YPSG+ LH GH   Y + D  +RFK
Sbjct  7    TAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSRFK  66

Query  66   RMQGYNVFQPMGFDAFGLPAENYAIKTGIHPKDSTFKNIETMETQLKAMGAMFNWENEVI  125
            R QG NV++PMG DAFGLPAE+YA+ TG +P + T  NI     Q++A+G  ++W+ EV 
Sbjct  67   RAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDREVN  126

Query  126  TCSPDYYKWTQWLFLKLYEKGLAYKKKAPVNWCPSCNTVLANEQVL-DGKCERCDSNVDK  184
            T  P+YYKWTQW+F KLYEKGLAY    PVNW     T +ANE+VL DG  ER +  V +
Sbjct  127  TTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVR  186

Query  185  KNLEQWFLKITDYAdellekldeldWPEKTKAMQKHWIGKSVGAEVTFNVADSDLSFNVF  244
            K + QW LKIT YA+ LLE L+E+DWPE  K MQ++WIGKS GA+VTF+V D+D  F VF
Sbjct  187  KPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVF  246

Query  245  TTRVDTLFGVTYVVLAPENDLVDKLTTPENKAEVESYKTQAKNQSDIERQSITREKTGVF  304
            TTR DTLFG TY VLAPE+ LVD +TT+++   V  YK QA  +SD+ R  +++EKTGV 
Sbjct  247  TTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVW  306

Query  305  SGSYAINPINGKKVPIWIGDYVLNTYGTGCVMAVPAHDERDFAFATKYNLPIERVIEGG-  363
            +GSYAINP+NGK +P+WI+DYVL +YGTG +MAVPAHDERD  FA ++NL I  V+EGG 
Sbjct  307  TGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGN  366

Query  364  -DSLPYTEYGKMVNSGEFDGLFGNKAKEAVISKLESMNLGRKKINYRLRDWLVSRQRYWG  422
             +  ++TE G  +NS+ +DGL    A   ++  LE+  +G  ++ YRLRDWL SRQRYWG
Sbjct  367  VEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWG  426

Query  423  APIPIIYCEKCGTVEVPIEQLPVELPYNVEFSPDGK--SPLGKCDDFINTTCPKCGGPAK  480
             PIPII  E   +  VP  +LP+ LP   ++ P G   SPL++  D ++ T    G  ++
Sbjct  427  EPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED-GVKGR  485

Query  481  READTLDTFVCSSWYYLRYPDNNNEKDAFNPELINKMLPVDKYVGGPEHACMHLLYARFI  540
            RE++T+     SSWYYLRY D +N     + EL+++ LPVD YVGG+EHA +HLLYARF 
Sbjct  486  RETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFW  545

Query  541  TKALRDMGYLNFDEPFLSLTHQGLILGP----------------------------DGL-  571
             K L D+G +   EPF  L +QG+ILG                             + L 
Sbjct  546  HKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEELE  605

Query  572  ----KMSKSKGNTISPDDYIKEFGADVFRMYLMFGFDYTEGGAWSDDAIKSIGKFVDRVE  627
                KMSKS  N ++PDD + ++GAD +R+Y MF      + AWS++++ +  KF+DRV 
Sbjct  606  QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVY  665

Query  628  RILENAREEIKNSKDNKSTMDKDEKELNYVRHHSIKSITEDIDKMQFNTSIARLMEFTNA  687
            R++             K   + +   L+ V ++++K++TE++D+M+FNT+IA+LM F NA
Sbjct  666  RLI-----------TTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNA  714

Query  688  LSKYLGSDTLRNASFLRESIIDFITLLAPFAPHFAEEQWE-LIGINSSIFNEKWPEFDPK  746
             +K        +  ++ +   +F+ L+APFAPH++EE W+ L +   SI    WP +D  
Sbjct  715  ANK--------EDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDES  766

Query  747  ALIKDEVEIAVQVNGKIRAKINIYTSSSEDEIKESALNNDDIKNSIGDKEIKKVIVIKNR  806
             L+ ++VEI VQ++GK++AK+ +    S +E++E AL N+ ++  I++K+I KVI + N+
Sbjct  767  KLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNK  826

Query  807  LVNIVAK  813
            LVNIV K
Sbjct  827  LVNIVIK  833

785) leuS in NC_009699


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  587 bits (2217),  Expect = 9e-169, Method: Compositional matrix adjust.
 Identities = 384/847 (46%), Positives = 542/847 (64%), Gaps = 59/847 (6%)

Query  6    TKIDEKWQKKWEENSLYKFNNDNLDKKLYVLEMFSYPSGSKLHAGHWFNYGPVDSWARFK  65
            T I+ KWQ  W +N  +K   D    K+Y L+MF+YPSG+ LH GH   Y + D  +RFK
Sbjct  7    TAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSRFK  66

Query  66   RMQGYNVFQPMGFDAFGLPAENYAIKTGIHPKDSTFKNIETMETQLKAMGAMFNWENEVI  125
            R QG NV++PMG DAFGLPAE+YA+ TG +P + T  NI     Q++A+G  ++W+ EV 
Sbjct  67   RAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDREVN  126

Query  126  TCSPDYYKWTQWLFLKLYEKGLAYKKKAPVNWCPSCNTVLANEQVL-DGKCERCDSNVDK  184
            T  P+YYKWTQW+F KLYEKGLAY    PVNW     T +ANE+VL DG  ER +  V +
Sbjct  127  TTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVR  186

Query  185  KNLEQWFLKITDYAdellekldeldWPEKTKAMQKHWIGKSVGAEVTFNVADSDLSFNVF  244
            K + QW LKIT YA+ LLE L+E+DWPE  K MQ++WIGKS GA+VTF+V D+D  F VF
Sbjct  187  KPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVF  246

Query  245  TTRVDTLFGVTYVVLAPENDLVDKLTTPENKAEVESYKTQAKNQSDIERQSITREKTGVF  304
            TTR DTLFG TY VLAPE+ LVD +TT+++   V  YK QA  +SD+ R  +++EKTGV 
Sbjct  247  TTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVW  306

Query  305  SGSYAINPINGKKVPIWIGDYVLNTYGTGCVMAVPAHDERDFAFATKYNLPIERVIEGG-  363
            +GSYAINP+NGK +P+WI+DYVL +YGTG +MAVPAHDERD  FA ++NL I  V+EGG 
Sbjct  307  TGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGN  366

Query  364  -DSLPYTEYGKMVNSGEFDGLFGNKAKEAVISKLESMNLGRKKINYRLRDWLVSRQRYWG  422
             +  ++TE G  +NS+ +DGL    A   ++  LE+  +G  ++ YRLRDWL SRQRYWG
Sbjct  367  VEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWG  426

Query  423  APIPIIYCEKCGTVEVPIEQLPVELPYNVEFSPDGK--SPLGKCDDFINTTCPKCGGPAK  480
             PIPII  E   +  VP  +LP+ LP   ++ P G   SPL++  D ++ T    G  ++
Sbjct  427  EPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED-GVKGR  485

Query  481  READTLDTFVCSSWYYLRYPDNNNEKDAFNPELINKMLPVDKYVGGPEHACMHLLYARFI  540
            RE++T+     SSWYYLRY D +N     + EL+++ LPVD YVGG+EHA +HLLYARF 
Sbjct  486  RETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFW  545

Query  541  TKALRDMGYLNFDEPFLSLTHQGLILGP----------------------------DGL-  571
             K L D+G +   EPF  L +QG+ILG                             + L 
Sbjct  546  HKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEELE  605

Query  572  ----KMSKSKGNTISPDDYIKEFGADVFRMYLMFGFDYTEGGAWSDDAIKSIGKFVDRVE  627
                KMSKS  N ++PDD + ++GAD +R+Y MF      + AWS++++ +  KF+DRV 
Sbjct  606  QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVY  665

Query  628  RILENAREEIKNSKDNKSTMDKDEKELNYVRHHSIKSITEDIDKMQFNTSIARLMEFTNA  687
            R++             K   + +   L+ V ++++K++TE++D+M+FNT+IA+LM F NA
Sbjct  666  RLI-----------TTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNA  714

Query  688  LSKYLGSDTLRNASFLRESIIDFITLLAPFAPHFAEEQWE-LIGINSSIFNEKWPEFDPK  746
             +K        +  ++ +   +F+ L+APFAPH++EE W+ L +   SI    WP +D  
Sbjct  715  ANK--------EDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDES  766

Query  747  ALIKDEVEIAVQVNGKIRAKINIYTSSSEDEIKESALNNDDIKNSIGDKEIKKVIVIKNR  806
             L+ ++VEI VQ++GK++AK+ +    S +E++E AL N+ ++  I++K+I KVI + N+
Sbjct  767  KLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNK  826

Query  807  LVNIVAK  813
            LVNIV K
Sbjct  827  LVNIVIK  833

786) Glo7428_4678 in NC_019745


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  586 bits (2214),  Expect = 2e-168, Method: Compositional matrix adjust.
 Identities = 375/828 (46%), Positives = 558/828 (68%), Gaps = 29/828 (3%)

Query  5    YNPAAIEEKWQQTWVELGLDQTQTDSAKPKFYALSMFPYPSGS-LHMGHVRNYVITDVIA  63
            Y+ +AIE KWQ  W +    +T TD++KPKFYAL MFPYPSG+ LH+GH   Y  TD+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RLKRMQGYRVLHPMGWDAFGLPAENAAIDRGIPPAKWTYQNIAQMRSQLQRLGLSIDWNR  123
            R+KR QG  VLHPMGWDAFGLPAE+ A+D G  PA  T +NIA+ + Q++ LG+S DW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVATCSPDYYKWTQWIFLQFLKAGLAYQKEAAVNWDPIDQTVLANEQVDSEGRSWRSGAK  183
            EV T  P+YYKWTQWIF ++   GLAY+ E +VNW     T +ANE+V ++G S R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  184  VERKLLRQWFLKITDYAEELLNDLDKLPGWPDRVKLMQANWIGKSIGAYLEFPIVGSDKK  243
            V RK +RQW LKIT YAE LL+DL+ + +WP+ +K MQ NWIGKS GA + F + ++DK 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  244  IGVYTTRPDTVYGVTYVVLAPEHPLTQRVTTPDQQASVEAFVQEVTNQSELERTAEDKPK  303
            + V+TTRPDT++G TY VLAPEH+L + +TT+DQ  +V  + ++ + +S+L RT   K K
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEK  302

Query  304  RGIPTGGKAINPFTSEEIPIWIADYVLYEYGTGAVMGVPAHDARDFQFAQEKNLPIKVVI  363
             G+ TG+ AINP  + E+P+WIADYVL  YGTGA+M+VPAHD RD +FA  K++ + ++ 
Sbjct  303  TGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFA--KQFNLDIIP  360

Query  364  IPENGDASAPLTAADVETGIVVNSGEFDGMISTDAKAAIVKHAEKHNFGHARVQYRLRDW  423
            + E G+      AA  E G+ +NS+ +DG+  + A A +V   E +  G+  V YRLRDW
Sbjct  361  VLEGGNVEE---AAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDW  417

Query  424  LISRQRYWGAPIPVVHCPNCGIVPVPDEDLPVELP--EDVEFTGRGGSPLAQL-DWVNVP  480
            L+SRQRYWG PIP++H  +    +VP+ +LP+ LP   D+  +G G SPLA++ DW++V 
Sbjct  418  LFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT  477

Query  481  CPTCGTPAKRETDTMDTFIDSSWYYLRYPDANNDLQAFDSAKTNDWMPVDQYVGGIEHAI  540
                G  ++RET+TM    +SSWYYLRY D++N  +  D    ++W+PVD YVGG EHA+
Sbjct  478  RED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  541  LHLLYSRFFTKVLRDRGLLNFDEPFQRLLTQGMVQGTTYKNPITGKYIPPAQVDPNDPK-  599
            LHLLY+RF  KVL D G++   EPFQ+L+ QGM+ GT+Y+++  G  ++  +V+  D   
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDS-RGALVATDKVEKRDGSF  595

Query  600  -DPETGEPLQVFYEKMSKSKYNGIDPEEVLAKYGVDTARMFILFKAPPEKDLEWEDADVE  658
             + ETGE L+    KMSKS  N ++P++V+ +YG DT R++ +F +P +  + W + ++E
Sbjct  596  FHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLE  655

Query  659  GQFRFLNRVWRLVNDYSNQPAVISQQELTKPEKELRRAIHTAIKAVTEDLDGEYQFNTAV  718
            G  +FL+RV RL+          +++        L +  + ++KAVTE++D + +FNTA+
Sbjct  656  GSRKFLDRVYRLIT---------TKEITEENSGALDKVYNETVKAVTEQVD-QMKFNTAI  705

Query  719  SELMKLSNALAEAQCKDSAIYAEGIQTLLILLAPFAPHIAEELWHSL-GNTESIHVQPWL  777
            ++LM     + +A  K+  ++++  + ++ L+APFAPH++EELW++L ++ ESI   PW 
Sbjct  706  AQLM----VFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWP  761

Query  778  QYDESALVADEITLVVQINGKKRGDLQVPAQADKAELEKFARESEAAQ  825
             YDES LV +++ +VVQI+GK ++ L V+ +  + EL+  A  +E  Q
Sbjct  762  SYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQ  809

787) Clocel_3293 in NC_014393


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  585 bits (2211),  Expect = 3e-168, Method: Compositional matrix adjust.
 Identities = 368/844 (44%), Positives = 554/844 (66%), Gaps = 57/844 (6%)

Query  5    TSIDKKWQDKWEAAKLYDFKEDSEKEKLYVLEMFSYPSGAQLHAGHWFNYGPVDSWARFK  64
            T+I+ KWQ  W     +    D+ K K+Y L+MF+YPSGA LH GH   Y + D  +RFK
Sbjct  7    TAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSRFK  66

Query  65   KMQGYNVFQPMGFDAFGLPAENYAIKTGIHPMDSTLKNIETMEKQLRAMGAMFNWDHEVV  124
            + QG NV++PMG DAFGLPAE+YA+ TG +P + T  NI    +Q+ A+G  ++WD+EV 
Sbjct  67   RAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDREVN  126

Query  125  TCKPDYYKWTQWLFLKLYEKNLAYRKNAPVNWCPSCNTVLANEQVI-DGHCERCDSEVTK  183
            T  P+YYKWTQW+F KLYEK LAY  + PVNW     T +ANE+V+ DG  ER +  V +
Sbjct  127  TTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVR  186

Query  184  KNLTQWFLKITDYADELLDGIDGLDWPEKTKAMQKHWIGKSKGAEATFKVKDSDLSFDVF  243
            K + QW LKIT YA+ LL++++ +DWPE  K MQ++WIGKS GA+ TFKVKD+D  F VF
Sbjct  187  KPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVF  246

Query  244  TTRVDTLNGVTYVVLAPESPLVDQVTTEENKSAVEAYKVETSKQSEIERQSITREKTGVF  303
            TTR DTL G TY VLAPE +LVD +TT ++  AV  YK ++S +S++ R  +++EKTGV 
Sbjct  247  TTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVW  306

Query  304  TGSYAINPITHAEVPIWVADYVLATYGTGAVMAVPAHDDRDFAFATKYNLPIIRVVEGDE  363
            TGSYAINP+   E+P+W+ADYVLA+YGTGA+MAVPAHD+RD  FA ++NL II V+EG++
Sbjct  307  TGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGN  366

Query  364  LPYTGYGN--LVNSGEF-NGKASDAAKEAIVKKLAENNLGGWKVNFRLRDWLVSRQRYWG  420
            +  +++ +  L  +++F +G    +A   +V  L  + +G  +V +RLRDWL SRQRYWG
Sbjct  367  VEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWG  426

Query  421  APIPMIHCDSCGIVPVPEKDLPVELPYDVEFAPDGK--SPLAKSESFVNTTCPKCGGPAH  478
             PIP+IH +     +VPE +LP+ LP   ++ P G   SPLA+    ++ T    G  ++
Sbjct  427  EPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED-GVKGR  485

Query  479  RDVDTLDTFVCSSWYFLRYVDNLNSEKAWDVDKVNAMVPVDKYVGGPEHATMHLLYARFV  538
            R+ +T+     SSWY+LRY+D  N+EK  D + ++  +PVD YVGG+EHA +HLLYARF 
Sbjct  486  RETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFW  545

Query  539  TKALRDMGLVNIDEPFKSLTHQGLILGP----------------------------DGL-  569
             K L D+G+V   EPF+ L +QG+ILG                             + L 
Sbjct  546  HKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEELE  605

Query  570  ----KMSKSKGNTISPDTYISEFGADVFRMYLMFGFDYTEGGPWSDDAIKSMARFVDRVE  625
                KMSKS  N ++PD  + ++GAD +R+Y MF      + +WS++++ +  +F+DRV 
Sbjct  606  QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVY  665

Query  626  RVITSAVEEMKKSGKTSIDKAEKDLNFVRHNTIKSVLFDMDKMQFNTSIARIMEFTNALS  685
            R+IT+   E+      ++DK       V ++T+K+V  ++D+M+FNT+IA++M F NA  
Sbjct  666  RLITT--KEITEENSGALDK-------VYNETVKAVTEQVDQMKFNTAIAQLMVFVNA--  714

Query  686  KYLNEEEKNSAFIKEVVIDYLRILAPFAPHFAEEMWETIGGNFSIFN-ESFPTFDEKALV  744
                  +K+  ++ +   ++++++APFAPH++EE+W+++ ++   ++  + P++DE  LV
Sbjct  715  -----ANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLV  769

Query  745  KDEVEIAIQVNGKIKAKIMVATGLEEDVIKETALADADVKAAIGDKTVAKVIVIKGRLVN  804
             ++VEI +Q++GK+KAK++VA +L  + ++E ALA+  V+A I++K + KVI +  +LVN
Sbjct  770  ENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVN  829

Query  805  IVVK  808
            IV+K
Sbjct  830  IVIK  833

788) leuS in NC_004113


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  585 bits (2210),  Expect = 4e-168, Method: Compositional matrix adjust.
 Identities = 392/854 (46%), Positives = 572/854 (67%), Gaps = 30/854 (3%)

Query  5    YDPQVIEAKWQQEWAARQLDRTDTDPQKPKFYALSMFPYPSG-NLHMGHVRNYTITDVIA  63
            YD   IE+KWQ  WA  +  +T+TD+ KPKFYAL MFPYPSG  LH+GH   YT TD+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RCRRMQGYRVLHPMGWDAFGLPAENAAIERGIHPRVWTQQNIGQMRQELQRLGLSYDWER  123
            R +R QG  VLHPMGWDAFGLPAE+ A++ G +P   T +NI++ +++++ LG+SYDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVTTCHPDYYRWTQWLFLEFFEAGLAYQKEAAVNWDPVDQTVLANEQVDSEGRSWRSGAL  183
            EV T +P+YY+WTQW+F  ++E GLAY+ E +VNW     T +ANE+V ++G S R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  184  VERRLLKQWFLKITAYAEELLNDLEQLTGWPERVKLMQANWIGQSRGAYLEFPIVGSDEK  243
            V R+ ++QW LKITAYAE LL+DLE++ +WPE +K MQ NWIG+S GA + F + ++D  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  244  IGVFTTRPDTVYGVTYVVLAPEHPLTLKVTTSRRRKTVEAFIASVQQESELERTAGDRPK  303
            + VFTTRPDT++G TY VLAPEH+L   +TTS +  +V  +       S+L RT   + K
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEK  302

Query  304  RGVATGGKALNPFTGEEIPIWIANYVLYEYGTGAVMGVPAHDERDFQFAKAHRLPIRQVI  363
             GV TG+ A+NP  G E+P+WIA+YVL  YGTGA+M+VPAHDERD +FAK   L I  V+
Sbjct  303  TGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL  362

Query  364  IPPDGKASTRLRAAYTEPGKLINSGQFDGMDSTAAKVAITEYATAQGWGREHVQYRLRDW  423
               +        AA+TE G  INS+ +DG+D ++A   + E   A+G G E+V YRLRDW
Sbjct  363  EGGNVEE-----AAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDW  417

Query  424  LISRQRYWGVPIPIIHCPQCGpvpvprselpvllpeeveF--TGRGPSPLAKLAAWRDVP  481
            L+SRQRYWG PIPIIH  +  + +VP SELP++LP   ++  +G G SPLA+++ W +V 
Sbjct  418  LFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT  477

Query  482  CPKCGGPAQRETDTMDTFIDSSWYYFRYADARNSEAPFDPAAIKDWLPVDQYVGGIEHAI  541
                G  ++RET+TM    +SSWYY+RY D++N+E   D   +K+WLPVD YVGG EHA+
Sbjct  478  RED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  542  LHLLYSRFFTKVLRDRQLVHVSEPFQRLLTQGMVQGRTYKNPRTGKYVIPSRIADLNQP-  600
            LHLLY+RF  KVL D  +V   EPFQ+L+ QGM+ G +Y+++R G  V   ++   + + 
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSR-GALVATDKVEKRDGSF  595

Query  601  TDPDTGEALEVVYEKMSKSKYNGVAPGDVIQQYGADTARMFILFKAPPEKDLEWDDADVE  660
             + +TGE LE    KMSKS  N V P+DV++QYGADT R++ +F +P +  + W + ++E
Sbjct  596  FHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLE  655

Query  661  GQFRFLNRVWRLVQTFKAKGGRLGQPLPATLTKAEKDLRRAIHTAIKEISEDIEGDYQLN  720
            G  +FL+RV RL+ T        G             L +  + ++K ++E+++ + ++N
Sbjct  656  GSRKFLDRVYRLITTKEITEENSG------------ALDKVYNETVKAVTEQVD-QMKFN  702

Query  721  TAVAELMKLSNALSSADCYTSGVYSEGIQTLLTLLAPFAPHISEELWHQLGGT-DSIHRQ  779
            TA+A+LM + NA +  D     ++S+  + ++ L+APFAPH++EELW+ L ++ +SI   
Sbjct  703  TAIAQLMVFVNAANKED----KLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYV  758

Query  780  PWPKADPTALVADEITLVIQVMGKTRGAIQVPATASQAELEEAAQHSEIGQRYLAGKTIK  839
            PWP  D + LV +++ +V+Q+ GK ++ + V+   S+ EL+E A  +E  Q  +AGK I 
Sbjct  759  PWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDII  818

Query  840  KIIVVPGKLVNFVL  853
            K+I VP KLVN+V+
Sbjct  819  KVIAVPNKLVNIVI  832

789) MHY_08640 in NC_021041


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  584 bits (2204),  Expect = 1e-167, Method: Compositional matrix adjust.
 Identities = 365/835 (44%), Positives = 549/835 (66%), Gaps = 69/835 (8%)

Query  2    DPNKPKYYVLEMFPYPSG-NLHMGHVRNYSIGDVIARYKTMNGFNVLHPMGFDAFGMPAE  60
            D++KPK+Y L+MFPYPSG  LH+GH   Y+  D+++R+K  +G NVLHPMG DAFG+PAE
Sbjct  28   DASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSRFKRAQGHNVLHPMGWDAFGLPAE  87

Query  61   NAAIKHGVSPSDWTEDNMANMTRQQKEMGLSYDWDRKVATCHEDYYKWTQWLFELFYKKG  120
            + A+  G  P++ T +N+AN  RQ + +G+SYDWDR V T + +YYKWTQW+F  +Y KG
Sbjct  88   QYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKG  147

Query  121  LAYKKKASANWCETCHTVLANEQVI-DGKCWRCDDTVVKKDLEQWFLKITDYADVLLKDL  179
            LAY    + NW E   T +ANE+V+ DG   R +  VV+K + QW LKIT YA+ LL DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  180  DKLEGWPNRVKIMQDNWIGRSEGAEFSFDVPDYNEKISVYTTRPDTVFGVSYVVLAAEHP  239
            + ++ WP+ +K MQ NWIG+S GA+ +F V D +  ++V+TTRPDT+FG +Y VLA+EH+
Sbjct  208  EEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHA  266

Query  240  LVKKFIKGKENEQEILKFIEEVHNMNEIERTSSESEKKGMFTGVYAINPFNGEKVPVWVT  299
            LV   I   ++ + +  +  +    +++ RT    EK G+ TG YAINP NG  +PVW++
Sbjct  267  LVDA-ITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAINPVNGKEMPVWIA  325

Query  300  NYVLFEYGTGAVMGVPTHDERDFMFAKKYNLPMKIVIQNKEHNLTLETMENAYVEDGELV  359
            +YVL  YGTGA+M+VP+HDERD  FAK++NL +  V++  + +      E A+ EDG  +
Sbjct  326  DYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVE------EAAFTEDGLHI  379

Query  360  ESGQFTGMNNRKAITAMIDWLEENNLGKRRVNYRLRDWLISRQRYWGAPIPIIYCPHCGE  419
            +S+ + G+++  AI+ M++WLE + +G+  V YRLRDWL+SRQRYWG PIPII   +   
Sbjct  380  NSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTS  439

Query  420  VLVPEEQLPVKLP--KDVKFETGATSPLAQAEDFVNCTCPKCGAPAKRETDTMDTFICSS  477
              VPE +LP+ LP  KD++    + SPLA+  D ++ T    G  ++RET+TM     SS
Sbjct  440  TAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED-GVKGRRETNTMPQWAGSS  498

Query  478  WYYMRYADPHNDKAPFSKDAINYWLPVDQYIGGIEHAILHLLYSRFFTKVLKDAGLVEFD  537
            WYY+RY DPHN       + ++ WLPVD Y+GG EHA+LHLLY+RF  KVL D G+V   
Sbjct  499  WYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTK  558

Query  538  EPFTNLLTQGMVI-------------------KDGS---------------KMSKSKGNV  563
            EPF +L+ QGM++                   +DGS               KMSKS  NV
Sbjct  559  EPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNV  618

Query  564  VSPEEIIKKYGADTARLFILFAAPPERDLEWSDQGVEGAWRFIQRVWRIILSYADKVKEN  623
            V+P++++ +YGADT R++ +F +P +  + WS++G+EG+++F++RV R+I          
Sbjct  619  VNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLI----------  668

Query  624  PTFDVKALTKEEK-ELFRILNVTIEKVTEDIGTRSTFNTAISSIMELVNAFYVFKDGNLN  682
                 K +T E+   L ++ N T+  VTE+++ +  FNTAI+ +M +VNA    K+++L 
Sbjct  669  ---TTKEITEENSGALDKVYNETVKAVTEQVD-QMKFNTAIAQLMVFVNA--ANKEDKLF  722

Query  683  AGLAREVVINLIKLLAPFAPHVTEELWQQIGQTG-SVHHTTWPTFDPKATIADEVEVVVQ  741
            ++ A+     +++L+APFAPH+ EELWQ +  +G S+    WP++D    + ++VE+VVQ
Sbjct  723  SDYAK----GFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQ  778

Query  742  VNGKLRSKIMVSSSATREAQQEIALADEKIKGLIEGKTIVKVISVPKKLVNIVVK  796
            ++GK+++K++V+   +RE  QE+ALA+EK+++ I GK I+KVI+VP+KLVNIV+K
Sbjct  779  IKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

790) leuS in NC_009523


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  584 bits (2204),  Expect = 1e-167, Method: Compositional matrix adjust.
 Identities = 385/895 (44%), Positives = 576/895 (65%), Gaps = 72/895 (8%)

Query  14   DPSIEPKWREFWAREGIFKAGRRAGAPRRYILEMFPYPSG-DLHIGHLKNYVIGDALTRY  72
            + +IEPKW+ FWA +  FK+G  A+ P+ Y L+MFPYPSG +LH+GH   Y   D L+R+
Sbjct  6    HTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSRF  65

Query  73   YVIRGYDVLHPFGWDAFGLPAENAAIKYGRHPREWTYSNIAESKKSLEIAGIMYDWSREV  132
               +G +VLHP GWDAFGLPAE+ A+  G +P E T  NIA+ K+ ++  G+ YDW REV
Sbjct  66   KRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDREV  125

Query  133  TTCNPDYYRWNQWLFLLLYRKGLAYRAKATVNWDPVDQTVLANEQVDAEGRSWRSGAKVE  192
             T +P+YY+W QW+F  LY KGLAY A   VNW     T +ANE+V ++G S R+G  V 
Sbjct  126  NTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVV  185

Query  193  KRELEQWFFRITAYAERLLNDLDKLDRWPENVKTMQRNWIGRSEGAEVTFlalppgadly  252
            ++ + QW ++ITAYAERLL+DL+ +D WPE++K MQRNWIG+S GA+VTF     + D+ 
Sbjct  186  RKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKDF-  243

Query  253  appppdaeplVVFTTRPDTLWGATFMVLAPEHPLAPKLTAPERRAEVEAYIARARMESEI  312
                       VFTTRPDTL GAT+ VLAPEH+L   +T++++   V  Y  +A + S++
Sbjct  244  ----------TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDL  293

Query  313  ERTSATREKSGVFLGSYAINPVNDERIPIWIADYVLMGYGTGAIMAVPAHDQRDFEFARQ  372
             RT  ++EK+GV  GSYAINPVN+  +P+WIADYVL +YGTGAIMAVPAHD+RD EFA+Q
Sbjct  294  ARTDLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQ  353

Query  373  FGLPVRVVVQPPGETLDGDTMTEAWPGDGVMVNSGPINGIPVGKGEGQSVKAAIAWLEAQ  432
            F L +  V++  G  ++  + TE    DG+ +NS+ ++G+    + + ++   + WLEA+
Sbjct  354  FNLDIIPVLE--GGNVEEAAFTE----DGLHINSDFLDGL----DKASAIAKMVEWLEAE  403

Query  433  GKGKGTVTYRLRDWLISRQRYWGTPIPMLHLPDGTIKPVPEDQLPVLLPEVQDYLPKGK-  491
            G G+  VTYRLRDWL+SRQRYWG PIP++H  DGT  +VPE +LP++LP  +D  P G  
Sbjct  404  GVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTG  463

Query  492  -SPLAAAEHWVNTIDPETGQPARRDTDTMDTFVDSSWYFLRFCDAQNDREIFSREAARQW  550
             SPLA   +W++ +  E G  +RR+T+TM    +SSWY+LR+ D++N   +   E  +QW
Sbjct  464  ESPLANVTDWLE-VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQW  522

Query  551  MPVDQYIGGVEHAILHLLYARFITKVLYDEGLVPEDEPFKALFTQGMVQRRVRTPLDIVA  610
            +PVD Y+GG EHA+LHLLYARF  KVLYD G+VP  EPF+ LF QGM+            
Sbjct  523  LPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMI------------  570

Query  611  PGMVRFPEELRRKLELPAEAQTVDQARALLKERGYTLEEESDGGLTAVSGPVTMSKSAGN  670
                 +    R        ++ V++     ++ ++ ++ E++  L    +P  MSKS  N
Sbjct  571  -----LGTSYRDSRGALVATDKVEK-----RDGSF-FHVETGEELE--QAPAKMSKSLKN  617

Query  671  GIPVGPFVRQYGSDVARIVVLFAAPPENSMEWTDEGVAGAQRFLNRIVALFGPDRDEIAA  730
             +  +  V QYG+D  R+  +F +P + S+ W++EG+ G+++FL+R+  L+         
Sbjct  618  VVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTK------  671

Query  731  MVRSGNGAAPEGEDRALYRKLHETIRKVTLDTEQFRFNTAIAALMELLNEASRYRAEVGR  790
                      E +  AL +  +ET++ VT + +Q +FNTAIA LM ++N A++       
Sbjct  672  -------EITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANK-------  717

Query  791  VTPVFAQTAATFARLLSPFAPHLAEEV-HSWCGGTGSVYDAGWPEWDESALVLDEVEIVL  849
               +F++ A  F +L++PFAPHL+EE+ ++  ++  S+    WP  DES LV ++VEIV+
Sbjct  718  EDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVV  777

Query  850  QVNGKLRGKIMAPAGADEEQLREWALTNPRVLSFVGDKTVRKVIVVPGKLVNVVV  904
            Q++GK+++K++ + +   E+L+E AL+N +V + +++K + KVI VP KLVN+V+
Sbjct  778  QIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

791) leuS in NC_009482


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  584 bits (2204),  Expect = 1e-167, Method: Compositional matrix adjust.
 Identities = 375/862 (44%), Positives = 560/862 (65%), Gaps = 40/862 (4%)

Query  8    YSPTSLEPKWQQRWQEMGLDQTPEPSAERAE-NFYALSMFPYPSG-NLHMGHVRNYVITD  65
            Y  T++EPKWQ  W +   ++T   +++ +  +FYAL MFPYPSG  LH+GH   Y  TD
Sbjct  4    YDHTAIEPKWQAFWAD---NHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  66   VIARLMRLKGKRVLHPMGWDAFGLPAENAAIERGVDPADWTDRNIAQMREQLQRLGLSID  125
            +++R+ R +G  VLHPMGWDAFGLPAE+ A++ G DPA+ T  NIA+ + Q++ LG+S D
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  126  WSREVATCHSDYYRWTQWLFLQFLNADLAYRKEATVNWDPIDQTVLANEQVDADGRSWRS  185
            W REV T +++YY+WTQW+F ++ + +LAY  E  VNW     T +ANE+V +DG S R+
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  186  GALAEKRKLRQWFLKITAVADELLDDLEQLKGWPERVRTMQANWIGRSSGATLRFAIEAD  245
            G    ++ +RQW LKITA A+ LL+DLE++ +WPE ++ MQ NWIG+S+GA + F +   
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDT  239

Query  246  GKQAIEVFTTRPDTVFGVSYVVLAPEHDLVDQLTSADQRQAVEAFRQSLQSISEQDRVAD  305
            +K+ + VFTTRPDT+FG +Y VLAPEH LVD +T++DQ +AV  +++     S+  R   
Sbjct  240  DKD-FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDL  298

Query  306  DRPKRGVATGGTVQHPFTGQAVPVWIADYVLPDYGTGAVMGVPAHDSRDFAFAKQYDLPI  365
             + K GV TG+   +P  G+ +PVWIADYVL+ YGTGA+M+VPAHD RD  FAKQ++L I
Sbjct  299  AKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDI  358

Query  366  TTVVVEPGQAPDSGEPSEAFTGLGELVGSADFDGLQGEEAKTAIIQAAEQRGVGAAKITF  425
               V+E G+  ++     AFT  G  + S  +DGL+   A + +++  E  GVG  ++T+
Sbjct  359  IP-VLEGGNVEEA-----AFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTY  412

Query  426  RLRDWLISRQRYWGCPIPVIHCDDCGVVPVPESDLPVELP--RDVDLSGSGGSPLERATE  483
            RLRDWL+SRQRYWG PIP+IH +D    +VPES+LP+ LP  +D+  SG+G SPL   T+
Sbjct  413  RLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTD  472

Query  484  WKQVRCPKCGKPATRETDTMDTFMCSSWYYLRYTDANNDSAAFTNASIDAWMPVDQYVGG  543
            W +V      K + RET+TM     SSWYYLRY D++N      +  +  W+PVD YVGG
Sbjct  473  WLEVTREDGVK-GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGG  531

Query  544  VEHAILHLLYSRFFTKVLQQRNLVSCSEPFQKLLTQGMVQGVTYRNPKTRKYIAPSAVSD  603
             EHA+LHLLY+RF  KVL +  +V+  EPFQKL+ QGM+ G +YR+++    +A   V  
Sbjct  532  AEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRG-ALVATDKVEK  590

Query  604  PNQP-TDPDDGEALEVFFEKMSKSKYNGVDPGAVVDRYGADTARMFILFKAPPEKDLEWD  662
             + +  + + GE LE    KMSKS  N V+P+ VV++YGADT R++ +F +P +  + W 
Sbjct  591  RDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWS  650

Query  663  DADVEGQFRFLQRIWRLCDGAKASGlqlqsplplpaeltpaetDLRRAVHTAIEAVSDDL  722
            + ++EG  +FL+R+ RL      +                    L +  + ++ AV++  
Sbjct  651  EEGLEGSRKFLDRVYRLITTKEITE--------------ENSGALDKVYNETVKAVTE--  694

Query  723  QGDELQFNTAVSELMKLSNAMAGQLEAVSTAVAQEAVRSlllllAPFAPHLADELWEQLQ  782
            Q D+++FNTA+++LM + NA   +       +  +  ++++ L+APFAPHL++ELW+ L 
Sbjct  695  QVDQMKFNTAIAQLMVFVNAANKE-----DKLFSDYAKGFVQLIAPFAPHLGEELWQALT  749

Query  783  GSG-SIHQQRWPEVDASALVRDTITVVLQVKGKVRGNLEVPAAISKDELEQVALASDVAQ  841
            +SG SI    WP  D S LV + + +V+Q+KGKV+++L V+  +S++EL++VALA++  Q
Sbjct  750  ASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQ  809

Query  842  KWLEGNAPKRVIVVPGKLVNLV  863
              + G+   +VI VP KLVN+V
Sbjct  810  AEIAGKDIIKVIAVPNKLVNIV  831

792) Desaci_4049 in NC_018068


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  584 bits (2207),  Expect = 6e-168, Method: Compositional matrix adjust.
 Identities = 375/869 (44%), Positives = 559/869 (65%), Gaps = 79/869 (9%)

Query  5    YLFTDVEPKWQKKWLEEKAYKTEESSQKPKYYALAMFPYPSG-DLHMGHVRNYSIVDVIA  63
            Y  T +EPKWQ  W ++ ++KT   + KPK+YAL MFPYPSG +LH+GH   Y+  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RFKRMQGFNVLHPIGWDSFGLPAENAAIKHQTPPADWTWKNIANMQRQLKGMGLSYDWDR  123
            RFKR QG NVLHP+GWD+FGLPAE+ A+     PA+ T  NIAN +RQ++++G+SYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVATCHPGYYKWTQWMFLEFYKHGLVYKKKAAVNWCPSCSTVLANEQVV-EGACERCDTL  182
            EV T +P YYKWTQW+F  +Y  GL Y    +VNW    +T +ANE+V+ +G+ ER +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VTKKNLEQWFFKITDYAEILLRDLDDLPGWPEKVKTMQRNWIGRSEGVEVQFALEDRPEK  242
            V +K + QW +KIT YAE LL DL+++ +WPE +K MQRNWIG+S G +V F + D    
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  FSVYTTRVDTLFGVSYVVLAPEHPLVLELVKGTKYEADVMSFIEKMNGLNEIARTSTEAE  302
            F+V+TTR DTLFG +Y VLAPEH+LV + +  +     V  +  + +  +++ART    E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALV-DAITTSDQAEAVADYKRQASLKSDLARTDLAKE  301

Query  303  KEGLFIGAYCLNPLSGKKLPIWVANYVLLEYGTGAVMGVPAHDERDFEFATKYQLPIQTV  362
            K G+  G+Y +NP++GK +P+W+A+YVL  YGTGA+M+VPAHDERD EFA +++L I  V
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  363  IVPSGSEPGEKDKPLEAAYTDDGIMVNSGSFDGLNSDKGWDKIADEVERLGVGQRKVNFR  422
            +  +  E        EAA+T+DG+ +NS+ +DGL+   +  K+ + +E  GVG+ +V +R
Sbjct  362  LEGGNVE--------EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYR  413

Query  423  LRDWLISRQRYWGAPIPMVYCETCGTVPVPEEQLPVMLPEDVVFK---TGENPLATSRSF  479
            LRDWL+SRQRYWG PIP++  E   + +VPE +LP++LP    ++   TGE+PLA     
Sbjct  414  LRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDW  473

Query  480  LETTCPKCGGAARRETDTMDTFACSSWYFLRYTDPRNTEAPFTKATVDQWMNVDQYVGGV  539
            LE T    G  +RRET+TM   A SSWY+LRY DP+NTE       + QW+ VD YVGG 
Sbjct  474  LEVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGA  532

Query  540  EHAILHLLYARFFTKGLRDFGYLTAKEPFQNLLTQGMV----------------------  577
            EHA+LHLLYARF  K L D+G + +KEPFQ+L+ QGM+                      
Sbjct  533  EHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRD  592

Query  578  ------------CMDGSKMSKSKGNIVSPEAIIGKYGADTARLFILFAAPPERDLEWSDQ  625
                            +KMSKS  N+V+P+ ++ +YGADT R++ +F +P +  + WS++
Sbjct  593  GSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEE  652

Query  626  GVEGCYRFLNRIWRLVAQYEPIIKGIGNAPSGAELEKEWANLDSAGKEMRRQSHLAIQRV  685
            G+EG  +FL+R+ RL++      K I +  SGA L+K   +              +++ V
Sbjct  653  GLEGSRKFLDRVYRLIT-----TKEITEENSGA-LDKVYNE--------------TVKAV  692

Query  686  TMDVGTRYNFNTAISTIMEWVNALYLYKEQPTANAFVGKEAIEGILLLLAPFAPHITEEL  745
            T +V+   +FNTAI+ +M     +++   +   + F   +   G++ L+APFAPH+ EEL
Sbjct  693  TEQVDQM-KFNTAIAQLM-----VFVNAANKEDKLF--SDYAKGFVQLIAPFAPHLGEEL  744

Query  746  WQGI-GHADSIHEHSWPTVDETALVQDEVTVVLQVNGKVRDRIQVPAEISAAELEKIVVS  804
            WQ++ + ++SI   +WP+ DE+ LV+++V +V+Q++GKV+ ++ V+ ++S  EL+ + ++
Sbjct  745  WQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALA  804

Query  805  QPKVLEWTQGKTIVKVITVPGKLVNIVVK  833
            + KV     GK I+KVI+VP KLVNIV+K
Sbjct  805  NEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

793) leuS in NC_009616


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  584 bits (2207),  Expect = 6e-168, Method: Compositional matrix adjust.
 Identities = 373/859 (44%), Positives = 548/859 (64%), Gaps = 68/859 (7%)

Query  4    YIPGEIEPKWQKVWAESKVFETPQRSDKKKFYNLVMFPYPSGT-LHVGHVKNYVIGDIVA  62
            Y    IEPKWQ  WA++  F T   + K KFY L MFPYPSG+ LHVGH   Y   DI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRMKGYNVLHPFGYDAFGLPAENAAIKNKIHPEVWTFKNIDIIRNQIKKIGISYDWSR  122
            R+KR +G NVLHP G DAFGLPAE+ A+    +P   T  NI  ++ QI+ +G+SYDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVITCTEEYYKWTQWIFLKLYENGLAYKKKAAVNWCPSCQTVLANEQVV-DGKCERCGTE  181
            EV T   +YYKWTQWIF KLYE+GLAY    +VNW     T +ANE+V+ DG  ER G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VTMKHLEQWYFKITDYAEKLLNDIDKLRGWPENVKIMQKNWIGKSTGAEIDFPVDRLDMK  241
            V  K + QW +KIT YAE+LL+D++ + +WPE++K MQ+NWIGKSTGA++ F V   D  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  242  IKVFTTRPDTIWGVTFMAIAPESPLVEMLVTDERKDELSQFLKKVSLEDRFKRTSLEAEK  301
            + VFTTRPDT+ G T+  +APE +LV+ + T ++ + ++++ ++ SL   + RT L  EK
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEK  302

Query  302  EGFFLGRYAINPVTGEKIPIYVANYILYEYGTGAIMAVPAHDQRDFDFAKKYGISIRVVI  361
             G   G YAINPV G  +P+ +A+Y+L  YGTGAIMAVPAHD+RD +FAK++ + I  V+
Sbjct  303  TGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL  362

Query  362  DNPEESIDVEKMEKAYEEEGIMVNSGPFNGMRSTLALEKIIEYLEEKGIGKRSVQYKLRD  421
            +      +VE  E A+ E+G+ +NS+ ++G+  + A+ K++E LE  G+G+ +V Y+LRD
Sbjct  363  EGG----NVE--EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  422  WLISRQRYWGAPIPIVYCEKCGIVPVPEKDLPVKLP--KDVEFLPTGQSPLSLDEQFLNT  479
            WL+SRQRYWG PIPI+  E     +VPE +LP+ LP  KD+    TG+SPL+   + L+ 
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  480  TCPKCGGPAKREADTMDTFVDSSWYYLRYINPKLEDKPFDTEDINYWMPVDQYIGGVEHA  539
            T    G  ++RE++TM    +SSWYYLRYI+P   +K  D E ++ W+PVD Y+GG EHA
Sbjct  477  TRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  540  VLHLLYSRFITKVLYDLGYLKFEEPFENLFTQGMI----YKDGW----------------  579
            VLHLLY+RF  KVLYDLG +   EPF++LF QGMI    Y+D++                
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSF  595

Query  580  --------------KMSKSKGNVVSPDEMIEKYGADTLRTYILFMAPPEKDAEWSDAGIE  625
                          KMSKS  NVV+PD+++E+YGADTLR Y +FM+P +    WS+ G+E
Sbjct  596  FHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLE  655

Query  626  GVNRFLKRLWNNIYSILPRIKDVKVEKIELKNKQEKDLRRKLHQSIKKITEDIEGGFKFN  685
            G  +FL R    +Y +        +   E+ + +   L +  ++++K +TE+++   KFN
Sbjct  656  GSRKFLDR----VYRL--------ITTKEITEENSGALDKVYNETVKAVTEQVD-QMKFN  702

Query  686  TAIAGlmelnnnlseylnsAKDLNLPLLRELVEKLTLILSPFAPHMAEEIWHDLGNDTLV  745
            TAIA            + +A + +  L+ +    +  +++PFAPH++EE+W+ L      
Sbjct  703  TAIA--------QLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGES  754

Query  746  VN-EEWPAYDENALKVDEVTVIIQINGKVRGKIQTKVDVSEGEIKKLAFENAKIASYVDG  804
            ++   WP+YDE+ L  ++V +++QI+GKV++K+    D+S  E++ +A+ N K+ + + G
Sbjct  755  ISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAG  814

Query  805  REIVKVIYVKNKLLNIVVK  823
            ++I+KVI V NKL+NIV+K
Sbjct  815  KDIIKVIAVPNKLVNIVIK  833

794) leuS in NC_010723


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  584 bits (2206),  Expect = 8e-168, Method: Compositional matrix adjust.
 Identities = 381/848 (45%), Positives = 560/848 (67%), Gaps = 58/848 (6%)

Query  6    TKIDEKWQKIWEENETYKFNPENLDKKLYTLEMFSYPSGAQLHAGHWFNYGPTDSWARLK  65
            T I+ KWQ +W +N+T+K   +    K+Y+L+MF+YPSGA LH GH   Y +TD  +R+K
Sbjct  7    TAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSRFK  66

Query  66   RMQGYNVFQPMGFDAFGLPAENYAIKTGIHPKDSTFKNIETMEKQLKSMGAMFNWENEVV  125
            R QG NV++PMG DAFGLPAE+YA+ TG +P + T  NI    +Q++++G  ++W+ EV 
Sbjct  67   RAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDREVN  126

Query  126  TCSPDYYKWTQWLFLKLYEKGLAYRKKAPVNWCPSCNTVLANEQVV-DGLCERCESEVIK  184
            T  P+YYKWTQW+F KLYEKGLAY    PVNW     T +ANE+V+ DG  ER    V++
Sbjct  127  TTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVR  186

Query  185  KDLTQWFFKITDYADELLDKLDGLDWPEKTKSMQKHWVGRSYGAQVTFKVKDSSLEFDVF  244
            K + QW +KIT YA+ LL+ L+ +DWPE  K MQ++W+G+S GA+VTFKVKD+  +F VF
Sbjct  187  KPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVF  246

Query  245  TTRVDTLNGVTYVVLAPENKLVDELTLPQykeavekykeeaskQSDIERQSSSREKSGVF  304
            TTR DTL G TY VLAPE+ LVD +T ++  EAV  YK +AS +SD+ R   ++EK+GV 
Sbjct  247  TTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVW  306

Query  305  TGSYAINPINGKEVPVWIADYVLATYGTGCVMAVPAHDERDFAFASKFNLPIERVITDKQ  364
            TGSYAINP+NGKE+PVWIADYVLA+YGTG +MAVPAHDERD  FA +FNL I  V+ + +
Sbjct  307  TGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGN  366

Query  365  DNEPALPFCEHGTLVNSGQFDGLTTDEAKKAIVSELEKDELGKMKVNFRLRDWLVSRQRY  424
             +E+A  F E+G  +NS+ +DGL    A   +V  LE + +G+ +V +RLRDWL SRQRY
Sbjct  367  VEEAA--FTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRY  424

Query  425  WGAPIPVIYCDECGIVPVPEKDLPVELPYNVEFTPDGK--SPLGKCEEFINTTCPHCGKP  482
            WG PIP+I  ++    +VPE +LP+ LP   ++ P G   SPL++  + ++ T  +  K 
Sbjct  425  WGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK-  483

Query  483  AKREADTLDTFVCSSWYYLRYPDNKNTDAPFDPELINKMLPVDKYVGGPEHACMHLLYAR  542
            ++RE++T+     SSWYYLRY D  NT+   D EL+++ LPVD YVGG+EHA +HLLYAR
Sbjct  484  GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYAR  543

Query  543  FITKALRDMGYLKFDEPFLSLTHQGLILGP----------------------------DG  574
            F  K L D+G +   EPF  L +QG+ILG                             + 
Sbjct  544  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEE  603

Query  575  L-----KMSKSKGNTISPDDYIKEFGADVFRMYLMFGFAYVEGGAWSDDGVKSVARFVDR  629
            L     KMSKS  N ++PDD + ++GAD +R+Y MF  +   + AWS++G+ +  +F+DR
Sbjct  604  LEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR  663

Query  630  IERTLESCRDIINASENIKTTIDSEEKDLNFWRHTAIKGVSEDAEKMQFNTAIARLMEFT  689
            + R L + ++I + +      + +E          ++K+V+E+ ++M+FNTAIA+LM F 
Sbjct  664  VYR-LITTKEITEENSGALDKVYNE----------TVKAVTEQVDQMKFNTAIAQLMVF-  711

Query  690  NALHKYIQADTKNPKFLKETVVDFLKLLAPFAPHFTEEQWNLLGHNSTIFN-EKWPEFNP  748
                  ++A  K+ K++ +   +F++L+APFAPH+ EE W+ L  ++  ++   WP ++ 
Sbjct  712  ------VNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDE  765

Query  749  AALVKDEVEIAIQVNGKIKAKIMIPSNLDEEGIKKASLENETIKANTEGKNiikvivikG  808
            + LV ++VEI +Q++GK+KAK++++ +L  E ++  +L NE ++A+  GK+IIKVI +  
Sbjct  766  SKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPN  825

Query  809  RLVNIVVK  816
            +LVNIV+K
Sbjct  826  KLVNIVIK  833

795) leuS in NC_013093


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  584 bits (2206),  Expect = 9e-168, Method: Compositional matrix adjust.
 Identities = 414/904 (46%), Positives = 596/904 (66%), Gaps = 90/904 (9%)

Query  35   TFHAPNPSGQLKGEVPADKLFVQDMFPYPSGAGLHVGHPLGFIGTDVYARYHRMTGRNVL  94
            +F A N + +   + +  K++  DMFPYPSGAGLHVGHP G+ +TD+ +R+ R  G+NVL
Sbjct  15   AFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSRFKRAQGHNVL  74

Query  95   HTMGFDAFGLPAEQYAVRTGQHPRETTKANIETYLRQIRRLGLGHDERRRISTIDPDYYR  154
            H MG DAFGLPAEQYA+ TG++P E T  NI  +             +R+I++++  Y  
Sbjct  75   HPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANF-------------KRQINALGFSY--  119

Query  155  WTQWIFLQIYNSWFDADVKKARPIAELVERFKSGERATPDGRPWAELSAAEQQKVLGEHR  214
              +W          D +V+ + P     + +K           W++   +     L E  
Sbjct  120  --DW----------DREVNTTDP-----NYYK-----------WTQWIFTK----LYEKG  147

Query  215  LAYLSEAPVNWCPGLGTVLANEEVTSDGRSERGNFPVFRRNLRQWMMRITAYSdrlvddl  274
            LAY +E PVNW   LGT +ANEEV +DG SERG +PV R+ +RQWM++ITAY++RL++DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  275  drldWPEKVKSMQRNWIGRSNGARVRFEVRAGEGAVGADERIEVFTTRPDTLFGATYVVL  334
            + +DWPE +K MQRNWIG+S GA V F V+      ++D  + VFTTRPDTLFGATY VL
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVK------DTDKDFTVFTTRPDTLFGATYAVL  261

Query  335  APEHPLVDaiaspaqagaiaaYRAEVARKSELDRQE-SKEKTGVPIGAVAVNPVNGAELP  393
            APEH+LVDAI+++ QA A+A Y+ + + KS+L R + +KEKTGV  G+ A+NPVNG E+P
Sbjct  262  APEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAINPVNGKEMP  321

Query  394  VYVADYVLMGYGTGAIMAVPGQDQRDWDFAKAFDLPIIRTVQPTEGFEGEAFTGVGPAIN  453
            V +ADYVL +YGTGAIMAVP++D+RDW+FAK F+L II  ++  +  E  AFT  G  IN
Sbjct  322  VWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNV-EEAAFTEDGLHIN  380

Query  454  SGFLDGMDVAEAKKAIIAWLEERGAGEGTVQYKLRDWLFSRQRYWGEPFPIVYDEDGTPI  513
            S+FLDG+D A A   ++ WLE  G G+  V Y+LRDWLFSRQRYWGEP+PI+  EDGT+ 
Sbjct  381  SDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTST  440

Query  514  ALPESHLPVVLPEVDDYSPRTFEPDDANSEPSPPLTRAQEWVEVELDLGDGPKRYRRETN  573
            A+PES+LP+VLP   D  P        ++   +PL+   +W+EV  +  DG K  RRETN
Sbjct  441  AVPESELPLVLPVTKDIRP--------SGTGESPLANVTDWLEVTRE--DGVKG-RRETN  489

Query  574  TMPNWAGSCWYQLRYVDPTEPGRFVDAENEQYWLGPRPAEHGANDPGGVDLYIGGVEHAV  633
            TMP+WAGS WY LRY+DP +  ++ D E  + WL              VD+Y+GG EHAV
Sbjct  490  TMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWL-------------PVDIYVGGAEHAV  536

Query  634  LHLLYSRFWQKVLFDLGHVSGDEPYRRLFNQGYIEAYAYTDARGAYVTAEEVVEKDGKFF  693
            LHLLY+RFW+KVL+DLG V+  EP+++LFNQG I + +Y D+RGA V+++ V  +DG FF
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFF  596

Query  694  H--DGAEVSREYGKMGKSLKNVVTPDEMCANYGADTFRVYEMSMGPMDVSRPWATKDVVG  751
            H   G E+ +  +KM+KSLKNVV PD++  +YGADT+RVYEM MGP+D S +W+  ++ G
Sbjct  597  HVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEG  656

Query  752  AQRFLQRLWRNLVDEDSGELRVADVEPSEDALRLLHKTIAGVHDDYANLRYNTAVAKLIE  811
            +++FL+R+ R +   +  E   + ++      ++ + T+ +V ++  ++++NTA+A+L+ 
Sbjct  657  SRKFLDRVYRLITTKEITEENSGALD------KVYNETVKAVTEQVDQMKFNTAIAQLMV  710

Query  812  LNNHVTKHYPAGAPRALAGPVVQLLAPLAPHVAEELWERLGGGGDSLAHGPFPVAEERYL  871
            + N   K+         A   VQL+AP+APH++EELW+ L ++G+S++  P P  +E  L
Sbjct  711  FVNAANKE--DKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKL  768

Query  872  VEDTVLYPVQVGGKVKARVTVSASASPDEVKaaalgdpavaallTG-EPRKVIVVPGRLV  930
            VE+ V   VQ+ GKVKA++ V+   S +E++  AL++  V A ++G +  KVI VP +LV
Sbjct  769  VENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLV  828

Query  931  NIVL  934
            NIV+
Sbjct  829  NIVI  832

796) leuS in NC_010674


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  583 bits (2201),  Expect = 2e-167, Method: Compositional matrix adjust.
 Identities = 378/848 (45%), Positives = 559/848 (66%), Gaps = 58/848 (6%)

Query  6    TKIDEKWQKIWEENETYKFNPENLDKKLYTLEMFSYPSGAQLHAGHWFNYGPTDSWARLK  65
            T I+ KWQ +W +N+T+K   +    K+Y+L+MF+YPSGA LH GH   Y +TD  +R+K
Sbjct  7    TAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSRFK  66

Query  66   RMQGYNVFQPMGFDAFGLPAENYAIKTGIHPKDSTFKNIETMEKQLKSMGAMFNWENEVV  125
            R QG NV++PMG DAFGLPAE+YA+ TG +P + T  NI    +Q++++G  ++W+ EV 
Sbjct  67   RAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDREVN  126

Query  126  TCSPDYYKWTQWLFLKLYEKGLAYRKKAPVNWCPSCNTVLANEQVV-DGLCERCESEVIK  184
            T  P+YYKWTQW+F KLYEKGLAY    PVNW     T +ANE+V+ DG  ER    V++
Sbjct  127  TTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVR  186

Query  185  KDLIQWFFKITDYADELLDKLDGLDWPEKTKSMQKHWVGRSYGAQVTFKVKDSSLEFDVF  244
            K + QW +KIT YA+ LL+ L+ +DWPE  K MQ++W+G+S GA+VTFKVKD+  +F VF
Sbjct  187  KPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVF  246

Query  245  TTRVDTLNGVTYVVLAPENKLVNELTLPQykeavekykeeaskQSDIERQSSSREKSGVF  304
            TTR DTL G TY VLAPE+ LV+ +T ++  EAV  YK +AS +SD+ R   ++EK+GV 
Sbjct  247  TTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVW  306

Query  305  TGSYAINPINGKEVPVWIADYVLATYGTGCVMAVPAHDERDFAFASKFNLPIERVITNKQ  364
            TGSYAINP+NGKE+PVWIADYVLA+YGTG +MAVPAHDERD  FA +FNL I  V+   +
Sbjct  307  TGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGN  366

Query  365  GDEPELPFCEHGILVNSGQFDGLTTDEAKKAIVSELEKDELGQMKVNFRLRDWLVSRQRY  424
             +E+  +F E+G+ +NS+ +DGL    A   +V  LE + +G+ +V +RLRDWL SRQRY
Sbjct  367  VEEA--AFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRY  424

Query  425  WGAPIPVIYCDECGIVPVPEKDLPVELPYNVEFTPDGK--SPLGKCEEFINTTCPHCGKP  482
            WG PIP+I  ++    +VPE +LP+ LP   ++ P G   SPL++  + ++ T  +  K 
Sbjct  425  WGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK-  483

Query  483  AKREADTLDTFVCSSWYYLRYPDNKNTDAPFDPELINKMLPVDKYVGGPEHACMHLLYAR  542
            ++RE++T+     SSWYYLRY D  NT+   D EL+++ LPVD YVGG+EHA +HLLYAR
Sbjct  484  GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYAR  543

Query  543  FITKALRDMGYLKFDEPFLSLTHQGLILGP----------------------------DG  574
            F  K L D+G +   EPF  L +QG+ILG                             + 
Sbjct  544  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEE  603

Query  575  L-----KMSKSKGNTISPDDYIKEFGADVFRMYLMFGFAYVEGGAWSDDGVKSVARFVDR  629
            L     KMSKS  N ++PDD + ++GAD +R+Y MF  +   + AWS++G+ +  +F+DR
Sbjct  604  LEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR  663

Query  630  IERTLESCRDIINASENIKTTIDSEEKDLNFWRHTAIKGVSEDAEKMQFNTAIARLMEFT  689
            + R L + ++I + +      + +E          ++K+V+E+ ++M+FNTAIA+LM F 
Sbjct  664  VYR-LITTKEITEENSGALDKVYNE----------TVKAVTEQVDQMKFNTAIAQLMVF-  711

Query  690  NAIHKYIQADTKNPTFLKETVVDFLKLLAPFAPHFTEEHWNLLGHNSTIFN-EKWPEFNP  748
                  ++A  K+  ++ +   +F++L+APFAPH+ EE W+ L  ++  ++   WP ++ 
Sbjct  712  ------VNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDE  765

Query  749  AALVKDEVEIAIQVNGKIKAKIMIPSNLDEEGIKKSSLENETIKANTEGKNiikvivikG  808
            + LV ++VEI +Q++GK+KAK++++ +L  E ++  +L NE ++A+  GK+IIKVI +  
Sbjct  766  SKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPN  825

Query  809  RLVNIVVK  816
            +LVNIV+K
Sbjct  826  KLVNIVIK  833

797) Amico_0688 in NC_014011


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  582 bits (2198),  Expect = 3e-167, Method: Compositional matrix adjust.
 Identities = 347/845 (42%), Positives = 554/845 (66%), Gaps = 73/845 (8%)

Query  3    YDFLSIEQKWQKVWEEENTFKVKADPSKKKFYCLEMFPYPSGA-LHMGHLRNYSIGDMMA  61
            YD  +IE KWQ  W +++TFK  +D+SK KFY L+MFPYPSGA LH+GH   Y+  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  62   RFLWMNGYNVLHPMGFDAFGLPAENAALKYGVQAHEWTHKNIEQMTDQLKRMGCSYDWDR  121
            RF + +G NVLHPMG DAFGLPAE+ A+  G ++ E T  NI +   Q++ +G SYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  122  RVETCNPDYYRWTQWIFLQFFKKGLAYRKKAPVNWCESCNTVLANEQVDSEGKCWRCNSP  181
             V+T +P+YY+WTQWIF +++ KGLAY    PVNW E   T +ANE+V ++G   R   P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VIKKKLEQWFFRITDYAQELLDDLDQLPGWPERVRIMQRNWIGRSEGARLTFTAKELGEE  241
            V++K + QW ++IT YA+ LL+DL+++ +WPE ++ MQRNWIG+S GA +TF  K+ + +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  242  IETFTTRFDTIFGVTFLALAPEHPLVDTILEKASNKEELETFVKTCISQSEIDRTAVGGE  301
            +  FTTR DT+FG T+  LAPEH+LVD+I   + + E +  + +    +S++ RT ++ E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAI-TTSDQAEAVADYKRQASLKSDLARTDLAKE  301

Query  302  KNGVFTGFYATNPATGEDVPIWIANYILMDYGTGAIMGVPAHDERDFDFARKYQIPVVAV  361
            K GV TG YA NP  G ++P+WIA+Y+L  YGTGAIM+VPAHDERD +FA+++++ +++V
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  362  IQPAEGDHLDGDTMSEAFVDNGIAFNSGEFNGLPTQEAIGRMLDWGEEKGFCTREVNFRI  421
            ++       +G+    AF ++G+ +NS+ ++GL    AI++M++W E  G    +V +R+
Sbjct  362  LE-------GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRL  414

Query  422  RDWLISRQRYWGAPIPIVYCDHCGMVPVPEKDLPVLLPTNLTVKEGGR--SPLAEADDWV  479
            RDWL+SRQRYWG PIPI+  ++    +VPE +LP++LP    ++ +G   SPLA+  DW+
Sbjct  415  RDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWL  474

Query  480  NTTCPVCGGHARREVDTMDTFICSSWYQFRYVDPRNDKKVFETDLANYWMPVDQYIGGIE  539
            + T    G  +RRE +TM     SSWY +RY+DP+N  K+ + +L + W+PVD Y+GG E
Sbjct  475  EVTRE-DGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAE  533

Query  540  HACMHLIYSRFFTKVFADLGLCNAREPFSNLLTQGMVI-------------------KDG  580
            HA +HL+Y+RF  KV+ DLG+  ++EPF +L+ QGM++                   +DG
Sbjct  534  HAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDG  593

Query  581  ---------------AKMSKSLGNVVDPDEIIQKFGADTARLFILFAAPPGNDLEWSEQG  625
                           AKMSKSL NVV+PD++++++GADT R++ +F +P +  + WSE+G
Sbjct  594  SFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEG  653

Query  626  VEGVHRFLNRVWRYI-EENLEGLKNASMERVEMGSLVNKDRRDFKRKIHKTIEDVTRDIQ  684
            +EG ++FL+RV R I   ++   +++++++V            ++  +    E+V     
Sbjct  654  LEGSRKFLDRVYRLITTKEITEENSGALDKV------------YNETVKAVTEQV-----  696

Query  685  EERQFNTAVARLMELLNSIYSCSPKDEKDWGLLREGVEVLLMCLNPFCPHITEELWQML-  743
            ++ +FNTA+A+LM ++N+    + K++K   L+ +    ++  + PF PH+ EELWQ L 
Sbjct  697  DQMKFNTAIAQLMVFVNA----ANKEDK---LFSDYAKGFVQLIAPFAPHLGEELWQALT  749

Query  744  GNQNRLALSAWPIKDEAALVLDSVTVVIQVNGKVRHKIDLPAGLSKDELQQKTLNEPTIQ  803
            ++ + ++  +WP  DE+ LV + V +V+Q++GKV+ K+ ++ +LS++ELQ+ +L +  +Q
Sbjct  750  ASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQ  809

Query  804  KRIEG  808
              I G
Sbjct  810  AEIAG  814

798) Clo1100_4071 in NC_016791


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  582 bits (2197),  Expect = 4e-167, Method: Compositional matrix adjust.
 Identities = 373/847 (45%), Positives = 549/847 (65%), Gaps = 57/847 (6%)

Query  5    ADIDRKWQKKWEETDIYKFDSENTDKKLYCLEMFSYPSGANLHVGHWYNYGLTDSWARMK  64
            + I+ KWQ  W + + +K +++ +  K+Y L+MF+YPSGA LHVGH   Y  TD  +R K
Sbjct  7    TAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSRFK  66

Query  65   RMQGYNVFHPMGFDAFGLPAENYAIKTGIHPQDSTLKNIETMEGQLKEMGATFDWDYEIK  124
            R QG NV+HPMG DAFGLPAE+YA+ TG +P + T  NI     Q++ +G ++DWD E++
Sbjct  67   RAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDREVN  126

Query  125  TCMPDYYKWTQWLFLQLYKSGLAYRKNAPVNWCPKCNTVLANEQVV-DGCCERCDSEVTK  183
            T  P+YYKWTQW+F +LY  GLAY  + PVNW     T +ANE+V+ DG  ER +  V +
Sbjct  127  TTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVR  186

Query  184  RDLTQWFFKITSYAQELLDKLDTIDWPEKTKKIQTNWIGRSEGAEISFKVDDTDIEFQVF  243
            + + QW +KIT+YA+ LL+ L+ +DWPE  K +Q NWIG+S GA+++FKV DTD +F VF
Sbjct  187  KPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVF  246

Query  244  TTRADTLYGVTYVVLAPENPIVEKITKPEYAEAVEKYKNDTKKQTEIERLSTTKEKTGVF  303
            TTR+DTL+G TY VLAPE+++V+ IT ++ AEAV  YK ++  ++++ R   +KEKTGV 
Sbjct  247  TTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVW  306

Query  304  TGSYAIHPITGEKVPVWIADYVLASYGTGCVMAVPSHDERDFEFAKKYSLTIKRVIKSAD  363
            TGSYAI+P+ G  +PVWIADYVLASYGTG +MAVP+HDERD EFAK+++L I  V+ +  
Sbjct  307  TGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEG--  364

Query  364  GSNDELPYCDYGVLVNSAEFDGVPSAEARTAIIKKLEVDGKGSLKINYRLRDWLVSRQRY  423
            G+ +E ++ + G+ +NS  +DG+  A A + ++  LE +G G+ ++ YRLRDWL SRQRY
Sbjct  365  GNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRY  424

Query  424  WGAPIPIVYCEHCGEVAVPEESLPVSLPYNVEFKPD--GESPLKKSEEFMNTVCPKCGAP  481
            WG PIPI+  E+    AVPE  LP+ LP   +++P   GESPL +  + ++ V    G  
Sbjct  425  WGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE-VTREDGVK  483

Query  482  AKRDPDTLDTFVCSSWYYLRYPDSQNNDKPFDTEWINKMLPVDKYVGGAEHAAMHLLYAR  541
            ++R+ +T+     SSWYYLRY D++N +K  D E +++ LPVD YVGGAEHA +HLLYAR
Sbjct  484  GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYAR  543

Query  542  FITKALRDLGFLNFDEPFLSLVHQGTILGP------------------------------  571
            F  K L DLG +   EPF  L +QG ILG                               
Sbjct  544  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEE  603

Query  572  ---DGNRMSKSRGNTISPDDYVRKYGSDIFRMYLGFGFNYVDGGPWSDDGIKAISRFASR  628
                  +MSKS  N ++PDD V +YG+D +R+Y  F      + +WS++G+ +  +F  R
Sbjct  604  LEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR  663

Query  629  IERLVESLAEQKAKASRTDMDKDDKELNYVRHTAIKGATQDTDRFQFNTAMSRCMELVNA  688
            + RL+         +++   + +   L+ V + ++K+ T++ D+ +FNTA+++ M +VNA
Sbjct  664  VYRLI---------TTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNA  714

Query  689  LYKYDAEVKVKNIQLFEDTIKDLVKLVSPFAPHFAEEMWEQL-GYEYSIFNQNWPEFDEN  747
                      K+ +LF D  K++V+L++PFAPH++EE+W+ L +   SI    WP +DE+
Sbjct  715  --------ANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDES  766

Query  748  ALVKDTIELAVQINGTVRGKIEVAADADNSEAEAVALADEKIKPFLDGKEikkvivvkGR  807
             LV + +E+ VQI+G V++K+ VA D    E + VALA+EK+++ + GK+I KVI V  +
Sbjct  767  KLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNK  826

Query  808  LVNIVAK  814
            LVNIV K
Sbjct  827  LVNIVIK  833

799) leuS in NC_007776


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  582 bits (2197),  Expect = 4e-167, Method: Compositional matrix adjust.
 Identities = 394/884 (45%), Positives = 593/884 (68%), Gaps = 61/884 (6%)

Query  5    YNPQAIESKWQAHWREIGLDRTPELKDGSRKFYALSMFPYPSG-NLHMGHVRNYTITDVI  63
            Y+  AIE+KWQA W +    +T     +  KFYAL MFPYPSG  LH+GH   YT TD++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGT-DASKPKFYALDMFPYPSGAGLHVGHPEGYTATDIL  62

Query  64   ARHKRMQGYAVLHPMGWDAFGLPAENAAIDRGIPPAKWTYQNIAQMREQLQRLGLSYDWE  123
            +R KR QG  VLHPMGWDAFGLPAE+ A+D G  PA  T +NIA+ + Q++ LG+SYDW+
Sbjct  63   SRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWD  122

Query  124  REITTCAPDYYKWTQWLFLQFFKAGLAYQKEAPVNWDPVDQTVLANEQVDAEGRSWRSGA  183
            RE+ T  P+YYKWTQW+F +++  GLAY+ E PVNW     T +ANE+V ++G S R+G 
Sbjct  123  REVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGY  182

Query  184  LVEKRMLKQWFFKITAYADQLLADLEKLSGWPERVRTMQENWIGQSVGAKVIFKT-EAGD  242
             V ++ ++QW +KITAYA++LL DLE + +WPE ++ MQ NWIG+S GA+V FK  +++ 
Sbjct  183  PVVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDK  241

Query  243  ELAVFTTRPDTLWGATFMVMSPEHPLVDKLTTAEqlqavrayqaqaaarseiersaEDRE  302
            +++VFTTRPDTL GAT+ V++PEH+LVD +TT++Q +AV  Y+ QA+ +S++ R+   +E
Sbjct  242  DFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKE  301

Query  303  KTGVWTGSYAINPVNQERIPIWIADYVLMGYGTGAIMAVPAHDQRDFEFARKFGLPIKRV  362
            KTGVWTGSYAINPVN   +P+WIADYVL +YGTGAIMAVPAHD+RD EFA++F L I  V
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  363  VQPPEGSLSSTDRASGTESSELQAAWTGEGVMINSGPLDGIPVGKGPGQSVERAIAWLEA  422
            ++  +                 +AA T +G+ INS+ LDG+    + + ++ + + WLEA
Sbjct  362  LEGGNVE---------------EAAFTEDGLHINSDFLDGL----DKASAIAKMVEWLEA  402

Query  423  QGLGEKQINYRLRDWLISRQRYWGCPIPVIHCPHCGIVPVPEKDLPVLLP--EDVELTGR  480
            +G+G+ ++ YRLRDWL+SRQRYWG PIP+IH  +    +VPE +LP++LP   D+  +G 
Sbjct  403  EGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGT  462

Query  481  GGSPLAQLEDWVKVKCPTCGAEARRETDTMDTFICSSWYFLRFSDARNDREIFRKDRVNA  540
            G SPLA++ DW+ V     G  +RRET+TM     SSWY+LR+ D++N   +   + ++ 
Sbjct  463  GESPLANVTDWLEVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQ  521

Query  541  WLPVDQYVGGIEHAILHLLYSRFFTKVLRDRGLLDFDEPFLRLLTQGMVQGRTYYNPNKS  600
            WLPVD YVGG EHA+LHLLY+RF  KVL D G++   EPF +L+ QGM+ G +Y    + 
Sbjct  522  WLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY----RD  577

Query  601  GKDRWIPAALVKDPDNP-TDPETGEPLEVIYATMSKSKGNGVDPEEVLAHYGADTARMFI  659
            +++  +++  V   D +  + ETGE LE   A MSKS  N V+P++V+ +YGADT R++ 
Sbjct  578  SRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYE  637

Query  660  LFKAPPEKDLEWDDADVEGQFRFLNRVWRQVYEFVVRGGGTESWRGRVSELLPAKVEVGS  719
            +F +P +  + W + ++EG  +FL+RV R                     L+ +K E+  
Sbjct  638  MFMGPLDASIAWSEEGLEGSRKFLDRVYR---------------------LITTK-EITE  675

Query  720  LTKAEKDLRRAIHTAIKEVSEDLENDYQFNTAIAELMKLSNALGEAGIPDSPVYAEGIRT  779
                   L +  + ++K V+E++++  +FNTAIA+LM     + +A+  +  ++++  + 
Sbjct  676  --ENSGALDKVYNETVKAVTEQVDQM-KFNTAIAQLM----VFVNAANKEDKLFSDYAKG  728

Query  780  LVLLMAPFAPHIAEELWQAL-GGADSVHRQSWPSYDPAALVADTVTIVIQVNGKLRGSFE  838
            +V L+APFAPH++EELWQAL ++++S+   +WPSYD + LV + V IV+Q++GK+++ + 
Sbjct  729  FVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLV  788

Query  839  APAEVTPEEQEQLALRSEAAQKYLEGATpkkvvvvpkkLVNFVL  882
             + +++ EE +++AL +E  Q  + G    KV+ VP+KLVN+V+
Sbjct  789  VAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

800) leuS in NC_010520


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  581 bits (2195),  Expect = 6e-167, Method: Compositional matrix adjust.
 Identities = 379/847 (45%), Positives = 541/847 (64%), Gaps = 59/847 (6%)

Query  6    TKIDEKWQKKWEESSLYKFNNENLDKKLYVLEMFSYPSGSKLHAGHWFNYGPVDSWARFK  65
            T I+ KWQ  W ++  +K   +    K+Y L+MF+YPSG+ LH GH   Y + D  +RFK
Sbjct  7    TAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSRFK  66

Query  66   RMQGYNVFQPMGFDAFGLPAENYAIKTGIHPKDSTFKNIETMETQLKAMGAMFNWENEVI  125
            R QG NV++PMG DAFGLPAE+YA+ TG +P + T  NI     Q++A+G  ++W+ EV 
Sbjct  67   RAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDREVN  126

Query  126  TCSPDYYKWTQWVFLKLYEKGLAYKKKAPVNWCPSCNTVLANEQVL-DGKCERCDSDVDK  184
            T  P+YYKWTQW+F KLYEKGLAY    PVNW     T +ANE+VL DG  ER +  V +
Sbjct  127  TTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVR  186

Query  185  KNLEQWFLKITDYAdellekldeldWPEKTKTMQKHWIGKSVGAEVTFNVADSDLSFNVF  244
            K + QW LKIT YA+ LLE L+E+DWPE  K MQ++WIGKS GA+VTF+V D+D  F VF
Sbjct  187  KPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVF  246

Query  245  TTRVDTLFGVTYVVLAPENDLVDKLTTPENKAEVESYKTQAKNQSDIERQSITREKTGVF  304
            TTR DTLFG TY VLAPE+ LVD +TT+++   V  YK QA  +SD+ R  +++EKTGV 
Sbjct  247  TTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVW  306

Query  305  SGSYAINPINGKKVPIWIGDYVLNTYGTGCVMAVPAHDERDFAFATKYNLPIERVIEGG-  363
            +GSYAINP+NGK +P+WI+DYVL +YGTG +MAVPAHDERD  FA ++NL I  V+EGG 
Sbjct  307  TGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGN  366

Query  364  -DSLPYAEYGKMINSEEFDGLSGNKAKETVISKLESMNLGRKKINYRLRDWLVSRQRYWG  422
             +  +++E G  INS+ +DGL    A   ++  LE+  +G  ++ YRLRDWL SRQRYWG
Sbjct  367  VEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWG  426

Query  423  APIPIVYCEKCGTVEVPMEQLPVELPYNVEFSPDGK--SPLSKCDQFINTTCPKCGGPAK  480
             PIPI+  E   +  VP  +LP+ LP   ++ P G   SPL++  + ++ T    G  ++
Sbjct  427  EPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED-GVKGR  485

Query  481  READTLDTFVCSSWYYLRYPDNKNEKDAFNPELINKMLPVDKYVGGPEHACMHLLYARFI  540
            RE++T+     SSWYYLRY D  N     + EL+++ LPVD YVGG+EHA +HLLYARF 
Sbjct  486  RETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFW  545

Query  541  TKALRDMGYLNFDEPFLSLTHQGLILGP----------------------------DGL-  571
             K L D+G +   EPF  L +QG+ILG                             + L 
Sbjct  546  HKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEELE  605

Query  572  ----KMSKSKGNTISPDDYIKEFGSDVFRMYLMFGFDYTEGGAWSDDAIKSIGKFVDRVE  627
                KMSKS  N ++PDD + ++G+D +R+Y MF      + AWS++++ +  KF+DRV 
Sbjct  606  QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVY  665

Query  628  RILENAReeiknsknnksnmdkdekeLNYVRHHSIKSITEDIDKMQFNTSIARLMEFTNA  687
            R++             K   + +   L+ V ++++K++TE++D+M+FNT+IA+LM F NA
Sbjct  666  RLITT-----------KEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNA  714

Query  688  LSKYLGSDTIKNASFLKESIIDFITLLAPFAPHFAEEQWE-LIGINSSIFNEKWPELDPK  746
                    + K+  ++ +   +F+ L+APFAPH++EE W+ L +   SI    WP  D  
Sbjct  715  --------ANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDES  766

Query  747  ALIKDEVEIAVQVNGKIRAKINISTSSSEDEIKESALNNDDIKNSIGDKEIKKVIVIKNR  806
             L+ ++VEI VQ++GK++AK+ ++   S +E++E AL N+ ++  I++K+I KVI + N+
Sbjct  767  KLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNK  826

Query  807  LVNIVAK  813
            LVNIV K
Sbjct  827  LVNIVIK  833

801) leuS in NC_015425


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  581 bits (2194),  Expect = 6e-167, Method: Compositional matrix adjust.
 Identities = 378/846 (45%), Positives = 562/846 (67%), Gaps = 58/846 (6%)

Query  6    TSVDKKWQKKWEESGLNNFDENAPGEKLYVLEMFSYPSAAKLHAGHWFNYGPTDSWARFK  65
            T+++ KWQ  W ++   + + +A+  K+Y L+MF+YPS+A LH GH   Y +TD  +RFK
Sbjct  7    TAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSRFK  66

Query  66   KMNGYNVFQPMGFDAFGLPAENFAIKTGVHPQDSTMKNIENMEEQLKSMGAMFNWDHEIV  125
            + +G NV++PMG DAFGLPAE++A+ TG +P + T  NI N   Q++++G  ++WD+E+ 
Sbjct  67   RAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDREVN  126

Query  126  TCLPDYYKWTQWVFLKLYEKGLAYRKNAPVNWCPSCNTVLANEQVI-DGHCERCDSEVEK  184
            T  P+YYKWTQW+F KLYEKGLAY  + PVNW     T +ANE+V+ DG  ER +  V +
Sbjct  127  TTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVR  186

Query  185  KALTQWFLKITDYAdellekldeldWPEKTKSMQKHWIGKSKGAEVTFKVENSDITFDVF  244
            K++ QW LKIT YA+ LLE L+E+DWPE  K MQ++WIGKS GA+VTFKV ++D  F VF
Sbjct  187  KPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVF  246

Query  245  TTRVDTLNGVTYVVLAPENELVDTLTTDDNKEAVNAYKIEAQKQSEIERQSSTREKTGVF  304
            TTR DTL G TY VLAPE+ LVD++TT D+ EAV  YK +A  +S++ R   ++EKTGV 
Sbjct  247  TTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVW  306

Query  305  TGSYAINPINGKKVPIWVGDYVLATYGTGCVMAVPAHDERDFAFATKYDLPIVRVIEGG-  363
            TGSYAINP+NGK +P+W++DYVLA+YGTG +MAVPAHDERD  FA +++L I+ V+EGG 
Sbjct  307  TGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGN  366

Query  364  -DSLPFTEYGPLVNSGDFDGLSSDKAKEAIVKKLQEQSLGNWKVNYRLRDWLVSRQRYWG  422
             +  +FTE G  +NS+ +DGL    A   +V  L+ +++GN +V YRLRDWL SRQRYWG
Sbjct  367  VEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWG  426

Query  423  APIPVVYCDKCGTVTIPESQLPVELPYNIEFTPDGK--SPLAKSEEFLHTTCPKCGGHAT  480
             PIP++  +   + ++PES+LP+ LP   ++ P G   SPLA+  + L+ T    G  + 
Sbjct  427  EPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED-GVKGR  485

Query  481  RETDTLDTFVCSSWYYLRYVDNNNSEKAFDIDKVNKMLPVDKYVGGPEHACMHLLYARFI  540
            RET+T+     SSWYYLRY+D +N+EK  D + +++ LPVD YVGG+EHA +HLLYARF 
Sbjct  486  RETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFW  545

Query  541  TKALRDMGYLNFDEPFKSLTHQGLILGP----------------------------DGL-  571
             K L D+G +   EPF+ L +QG+ILG                             + L 
Sbjct  546  HKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEELE  605

Query  572  ----KMSKSKGNTIAPDDYIKEFGADVFRMYLMFGFAYSEGGAWSDDAIKSMGRFIDKVE  627
                KMSKS  N + PDD + ++GAD +R+Y MF  +   + AWS++++ +  +F+D+V 
Sbjct  606  QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVY  665

Query  628  RLLDDARTELNNSKNTKTTMEKSEKELNYARHYAIQHVTEDTDKFQFNTAIARIMEYTNS  687
            RL+            TK   E +   L+   + +++ VTE+ D+ +FNTAIA++M + N+
Sbjct  666  RLI-----------TTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNA  714

Query  688  LSKYLNEENVNIEFLKEALCDYVKLLAPFTPHFSEEQWELLGNTPSIFT-SSWPVFDPKA  746
             +K   E+++  ++ K    ++V+L+APF+PH++EE W+ L  +   ++  +WP +D   
Sbjct  715  ANK---EDKLFSDYAK----GFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESK  767

Query  747  LIKDEVEIAIQILGKIKARMNIATNLTEDEIKEAALNNETIKELLEGKNVMKIIVVKGRL  806
            L+ ++VEI +QI GK+KA++ +A +L+ +E++E AL NE ++  + GK+++K+I V  +L
Sbjct  768  LVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKL  827

Query  807  VNIVAK  812
            VNIV K
Sbjct  828  VNIVIK  833

802) Plim_3733 in NC_014148


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  580 bits (2192),  Expect = 1e-166, Method: Compositional matrix adjust.
 Identities = 372/745 (50%), Positives = 511/745 (69%), Gaps = 62/745 (8%)

Query  195  LAYIHEAPVNWCPALGTVLANEEVTADGKSDRGNHPVERRNLKQWMLRITAYAERLIGEL  254
            LAY  E PVNW   LGT +ANEEV +DG S+RG  PV R+ ++QWML+ITAYAERL+ +L
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  255  DQVNWPESIKLLQRNWIGRSEGAEVDFVIDPASWRGKSAAGEEKLRVYTTRPDTLFGATY  314
            ++V+WPESIK +QRNWIG+S GA+V F         K    +  + V+TTRPDTLFGATY
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTF---------KVKDTDKDFTVFTTRPDTLFGATY  258

Query  315  MVLAPEHPLVDAITREDRVADVAAYRQKTSLKSDLDRTDLAKEKSGVFTGGYAINPVNGE  374
             VLAPEH+LVDAIT  D+   VA Y++++SLKSDL RTDLAKEK+GV TG+YAINPVNG 
Sbjct  259  AVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAINPVNGK  318

Query  375  KIPIWIADYVLMSYGTGAIMAVPAHDERDLEFATLFGIPVIPVVSPPEAPGEGLIGFTGA  434
             +P+WIADYVL SYGTGAIMAVPAHDERD EFA  F + +IPV+   +       +FT  
Sbjct  319  EMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEA---AFTED  375

Query  435  GIAVNSGPYSGLTTDEVKAQIVADLAAKGVAKKAVNYRLRDWLFSRQRYWGEPFPI--WH  492
            G+ +NS+   GL      A++V  L A GV++  V YRLRDWLFSRQRYWGEP+PI  W+
Sbjct  376  GLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWE  435

Query  493  ELDAQGEPTGMVRAVSASELPVKLPEMEDFKPTGTPEPLLSKAPAEWLYATAADGTKLKR  552
            +        G   AV+ SELP+ LP   D++P+GT E+ L++  ++WL  T  DG K +R
Sbjct  436  D--------GTSTAVPESELPLVLPVTKDIRPSGTGESPLANV-TDWLEVTREDGVKGRR  486

Query  553  ETNSMPQWAGSCWYYLRFCDNKNSERFIDPEKEKYWLPVDLYIGGAEHAVLHLLYSRFWH  612
            ETN+MPQWAGS WYYLR+ D  N+E++ D E  K WLPVD+Y+GGAEHAVLHLLY+RFWH
Sbjct  487  ETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWH  546

Query  613  KVLFDRGHVTHAEPFQRLVNQGMILGDLEFVAFQNPTGEFVTAKGTDVNRYIDAQGQTVI  672
            KVL+D G V   EPFQ+L NQGMILG     +++++ G +V+                  
Sbjct  547  KVLYDLGVVPTKEPFQKLFNQGMILG----TSYRDSRGALVA------------------  584

Query  673  PVKLKADDVEKQGDSFVLKSDPQIVVDARSFKMSKARRNVINPDQVVEQYGADSLRLYEM  732
                 +D VEK+++SF +  +    ++  + KMSK+ +NV+NPD+VVEQYGAD+LR+YEM
Sbjct  585  -----TDKVEKRDGSF-FHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEM  638

Query  733  FMGPLEATKPWSMSGVEGIYRFLGRVWRLIVDDQLDQVVLNSKVQPVEPSPAQNRILHKT  792
            FMGPL+A+ +WS  G+EG  +FL+RV RLI   ++ +          E S A +++ + T
Sbjct  639  FMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITE----------ENSGALDKVYNET  688

Query  793  IKAVTDDIERLSFNTAISRMMEFVNEFTAADVRPKIAMEKFVLLISPMAPHLAEELWEVL  852
            +KAVT++++++ FNTAI+++M FVN     D         FV LI+P APHL+EELW+ L
Sbjct  689  VKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQAL  748

Query  853  -GHEKSLAYEPWPEFDETLLEEATIEIPVQVNGKVRGKITIAKDataevveaaaaSDPHV  911
             +   S++Y PWP +DE+ L E  +EI VQ++GKV++K+ +AKD + E ++  A ++  V
Sbjct  749  TASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKV  808

Query  912  SSQLEGKTIVKKVYVPGRMMNFVVK  936
             +++ GK I+K + VP +++N+V+K
Sbjct  809  QAEIAGKDIIKVIAVPNKLVNIVIK  833


 Score =  194 bits (719),  Expect = 3e-50, Method: Compositional matrix adjust.
 Identities = 99/145 (69%), Positives = 118/145 (82%), Gaps = 0/145 (0%)

Query  1    MPRYDAARIEPKWQAYWDQHATFRTEMDVSKPKMYVLDMFPYPSGDGLHVGHPEGYTATD  60
            M  YD + IEPKWQA+W ++ TF+T  D SKPK Y LDMFPYPSG GLHVGHPEGYTATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   ITCRFARMRGKNVLHPMGWDAFGLPAEQYAVETGTHPRITTEKNIATFKRQLKSLGFSYD  120
            I  RF R +G NVLHPMGWDAFGLPAEQYA++TG +P   T  NIA FKRQ+++LGFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WERELATTDPDYVRWTQWIFLQLFD  145
            W+RE+ TTDP+Y +WTQWIF +L++
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYE  145

803) leuS in NC_013939


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  580 bits (2190),  Expect = 1e-166, Method: Compositional matrix adjust.
 Identities = 375/861 (44%), Positives = 552/861 (65%), Gaps = 41/861 (4%)

Query  3    YNPAEIEQKWQSKWESEKVFKCEADNSKKKYYCLEMFPYPSGK-IHMGHVRNYAIGDVIA  61
            Y+ + IE KWQ+ W  +  FK  +D SK K+Y L+MFPYPSG  +H+GH   Y+  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  62   RYKLMQDYNVLHPMGWDAFGLPAENAAIKNKVHPAKWTYSNIEYMKKQLKMLGLSYDWDR  121
            R+K  Q+ NVLHPMGWDAFGLPAE+ A+    +PA  T  NI   K+Q++ LG+SYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  122  EIATCDPEYYKWEQKIFIEMFNKGLAYKKTSLVNWCPDCNTVLANEQV-EDGKCWRCSNE  180
            E+ T DP+YYKW Q IF  +++KGLAY     VNW  +  T +ANE+V  DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  181  VEIKEIEGWFFKITDYAEELLEYTYKLSGWPERVLTMQRNWIGKSVGAEIDFKVDGIDEK  240
            V  K +  W +KIT YAE LLE      +WPE +  MQRNWIGKS GA++ FKV + D  
Sbjct  184  VVRKPMRQWMLKITAYAERLLE-DLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  241  ITVFTTRPDTLYGATFMSIAPEHPIAKKLLSGTEVEKDGLAFINEILKEDKISRTAEDKE  300
            +TVFTTRPDTL+GAT+  +APEH++   + ++ + E  +  +  +      ++RT   KE
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVA-DYKRQASLKSDLARTDLAKE  301

Query  301  KKGFFTGRYAINPVNGMKIPIYIANFVLMDYGTGAVMAVPAHDQRDFEFAKKYGLDIIVV  360
            K G  TG YAINPVNG  +P+ IA++VL  YGTGA+MAVPAHD+RD EFAK++ LDII V
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  361  IQPDGEQLDPEKMTEAYTGPGKMVNSGKFDGLDNEKGKEEVIKYLEELGVGKKTVNYRLK  420
            +  +G +++      A+T  G  +NS+ +DGLD+  +   ++  LE  GVG+  V YRL+
Sbjct  362  L--EGGNVE----EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  421  DWGISRQRYWGTPIPIIYCDDCGAVPVPFEDLPVKLPTDVEITGAG---NPLEQCEEFVK  477
            DW +SRQRYWG PIPII  +D  + +VP  +LP+ LP   +I  +G   +PL +  + + 
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  478  VKCPKCGKDARRETDTMDTFVESSWYFLRYCSPHCDTNIFDKDETEYWMPVDQYIGGIEH  537
            V      K +RRET+TM     SSWY+LRY  PH   ++ D +    W+PVD Y+GG EH
Sbjct  476  VTREDGVK-GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEH  534

Query  538  AILHLLYSRFYTKVLRDLGYINFDEPFERLLTQGMVCKESYRCEEHNWLFPEEVIDGKCK  597
            A+LHLLY+RF  KVL DLG +   EPF++L+ QGM+   SYR      L + + ++ +  
Sbjct  535  AVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGA-LVATDKVEKRDG  593

Query  598  ---HCGRDVIIGRI-EKMSKSKKNVVDPEALIDQYGADTARLFSLFAAPPEKDLEWSEQG  653
               H   +  + +   KMSKS KNVV+P+ +++QYGADT R++ +F +P +  + WSE+G
Sbjct  594  SFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEG  653

Query  654  VEGAFRFINRVWRLVVNHIDLIKEYYGKSYNVDGKLEKEILYHTHLTVKKVTNDIERFQL  713
            +EG+ +F++RV RL+    ++  E         G L+K  +Y+   TVK VT+++++ ++
Sbjct  654  LEGSRKFLDRVYRLITTK-EITEE-------NSGALDK--VYNE--TVKAVTEQVDQMKF  701

Query  714  NTAVAAIMEFTNNLYLIEPKLASESEKALFADALVKLIKIISPFIPHVAEELWNR-CGFE  772
            NTA+A +M F N         A++ E  LF+D    ++++I+PF PH++EELW+   +  
Sbjct  702  NTAIAQLMVFVN---------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASG  752

Query  773  GYVSKADWPAYDDKFTVKDEITIAVQINGKVRAQINVPRDIEKDEAIRLAKENEKVKNYI  832
              +S   WP+YD+   V +++ I VQI+GKV+A++ V++D+ ++E   +A  NEKV+  I
Sbjct  753  ESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEI  812

Query  833  DGKQLIKEIYVPNKLVSLVVK  853
             GK++IK I VPNKLV++V+K
Sbjct  813  AGKDIIKVIAVPNKLVNIVIK  833

804) Ple7327_3352 in NC_019689


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  580 bits (2192),  Expect = 1e-166, Method: Compositional matrix adjust.
 Identities = 371/867 (43%), Positives = 555/867 (65%), Gaps = 44/867 (5%)

Query  5    YNPANIEQKWQRKWEESGLYLTPENNTQPKFYALSMFPYPSGS-LHMGHVRNYVITDTIA  63
            Y+ + IE KWQ  W ++  + T  + ++PKFYAL MFPYPSG+ LH+GH   Y  TD ++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYKRMQGYRVLHPMGWDAFGLPAENAAIKRGIPPAKWTYQNIAQMKKQLQQLGLSIDWSR  123
            R+KR QG  VLHPMGWDAFGLPAE+ A+  G  PA  T +NIA+ K+Q++ LG+S DW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCAPNYYKWTQWIFLQFFKAGLAYQKEAAVNWDPVDQTVLANEQVDSEGRSWRSGAI  183
            E+ T  PNYYKWTQWIF +++  GLAY+ E +VNW     T +ANE+V ++G S R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  184  VERKLLRQWFLKITDYAEQLLNDLEKLTGWPERVKLMQANWIGKSVGAYLEFPIVGMEEK  243
            V RK +RQW LKIT YAE+LL+DLE + +WPE +K MQ NWIGKS GA + F + + +  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  244  IGVFTTRPDTVYGVTYVVLAPEHPLTPKVTTPDRKEAVEAFIQEVKGESEIERTAEDKPK  303
            + VFTTRPDT++G TY VLAPEH+L   +TT+D+ EAV  + ++    S++ RT   K K
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEK  302

Query  304  RGIFTGGKAINPFNGEEIPILIANYVLYEYGTGAVMGVPAHDTRDFKFANENNLPIKTVI  363
             G+ TG+ AINP NG E+P+ IA+YVL  YGTGA+M+VPAHD RD  FA++ NL I  V+
Sbjct  303  TGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL  362

Query  364  VSEGKDGTKPLETAYTDPGIMINSGQFDGMPSTEGKTAIIEYAEKQGYGKARVQYRLRDW  423
                 +G +  E+A+T+ G+ INS+ +DG+  + + + ++E  E +G G+  V YRLRDW
Sbjct  363  -----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDW  417

Query  424  LISRQRYWGAPIPIVHCPSCGIVPVPEEDLPVKLP--EDVEFTGRGPSPLAKLESWVNVP  481
            L+SRQRYWG PIPI+H       +VPE +LP+ LP   D+  +G G SPLA++  W++V 
Sbjct  418  LFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT  477

Query  482  CPSCGEAAKRETDTMDTFIDSSWYFLRYTDANNDKEIFASDKVNSWMPVDQYVGGIEHAI  541
                G  ++RET+TM    +SSWY+LRY D++N   +   + ++ W+PVD YVGG EHA+
Sbjct  478  RED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  542  LHLLYSRFFTKVLRDRGLLNFDEPFQRLLTQGMVQGLTYMNPNKSDKDKWIPAELVNPKD  601
            LHLLY+RF  KVL D G++   EPFQ+L+ QGM+ G +Y    +  ++  ++++ V+ +D
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY----RDSRGALVATDKVEKRD  592

Query  602  PR--DPQTGEPLQLVYATMSKSKGNGVAPEEVIAKYGVDTARMFILFKAPPEKDLEWDEA  659
                + +TGE L+   A MSKS  N V P++V+ +YG DT R++ +F +P +  + W E 
Sbjct  593  GSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEE  652

Query  660  DVEGQFRFLNRVWRLVAEFVEKSSPIGkkqsknqspsskGRNPKSKIEKDLRRAIHTAIK  719
            ++EG  +FL+RV RL++                       ++        L +  + ++K
Sbjct  653  GLEGSRKFLDRVYRLIT----------------------TKEITEENSGALDKVYNETVK  690

Query  720  EVSADLEGDYQFNTAISELMKLSNALGEAKCCDSPVYAEGIETLLILLAPFAPHIAEELW  779
             V+ +++ + +FNTAI++LM + NA       +  ++++    ++ L+APFAPH++EELW
Sbjct  691  AVTEQVD-QMKFNTAIAQLMVFVNAANK----EDKLFSDYAKGFVQLIAPFAPHLGEELW  745

Query  780  HELGHDC-SIHQQSWLQVDPLALQVDEITLVIQIMGKTRGTIQVPASADKAALEKYARES  838
            + L     SI   +W   D   L  +++ +V+QI GK ++ + V+    +  L+  A  +
Sbjct  746  QALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALAN  805

Query  839  EIAQRYLQGKEVKKIIVVPGKLVNFVV  865
            E  Q  + GK++ K+I VP KLVN+V+
Sbjct  806  EKVQAEIAGKDIIKVIAVPNKLVNIVI  832

805) Toce_0772 in NC_014377


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  580 bits (2189),  Expect = 2e-166, Method: Compositional matrix adjust.
 Identities = 380/856 (45%), Positives = 572/856 (67%), Gaps = 62/856 (7%)

Query  1    MSHYDFKTVELKWQKRWEEQKLYKVNEDDKKPKYYCLEMFPYPSGK-LHMGHVRNYSIGD  59
            M+ YD  ++E KWQ  W ++  +K   D  KPK+Y L+MFPYPSG  LH+GH   Y+  D
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  60   VVARFKRMKGYNVLHPMGWDAFGLPAENAAIKHGVHPARWTWDNIANMRKQLKQLGLSYD  119
            +++RFKR +G NVLHPMGWDAFGLPAE+ A+  G +PA  T +NIAN ++Q++ LG+SYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  120  WDREIATCHPGYYKWTQWFFLKLYEMGLAYRKKSFVNWCPSCATVLANEQVV-DGRCERC  178
            WDRE+ T +P YYKWTQW+F KLYE GLAY     VNW    +T +ANE+V+ DG  ER 
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  179  GAEVGKKNLEQWFFKITEYADQLLEDLKKLPGWPEKVKVMQENWIGRSEGVEVYFTAEKT  238
            G  V +K + QW +KIT YA++LLEDL  + +WPE +K MQ NWIG+S G +V F    T
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDT  239

Query  239  GEKIPVFTTRPDTIFGVTYLVLAPEHPMVDKLASGTPYENEVREFQKKMEKLNEITRTST  298
            +  + VFTTRPDT+FG TY VLAPEH++VD ++++    + V +++++    ++++RT  
Sbjct  240  DKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQ-AEAVADYKRQASLKSDLARTDL  298

Query  299  ETEKEGVFIGAYAVNPVTNERIPVWIANYVLPDYGTGAVMGVPAHDQRDFEFARKYGLPL  358
              EK GV  G+YA+NPV    +PVWIA+YVL+ YGTGA+M+VPAHD+RD EFA+++ L  
Sbjct  299  AKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLD-  357

Query  359  KVVINPLGESLCPENMTQAYVDEGILVNSGMFDGMKNTDAIQAIGRYMEEKGIGKIRVNY  418
              +I  L  +   E    A+ ++G+ +NS+ +DG+ ++ AI  +   +E  G+G+  V Y
Sbjct  358  --IIPVLEGGNVEEA---AFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTY  412

Query  419  KLRDWLISRQRYWGAPIPIVYCDKCGIVPVPEDQLPVMLPDDVEFNPKGT--SPLLECEE  476
            +LRDWL+SRQRYWG PIPI+  +     +VPE +LP++LP   ++ P GT  SPL +  +
Sbjct  413  RLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTD  472

Query  477  FLNTTCPKCGGPARRETDTMDTFMCSSWYYYRYTDPRNEEKPFDREKLEYWMPVDQYIGG  536
             L+ T    G  +RRET+TM     SSWYY RY DP+N EK  D E L  W+PVD Y+GG
Sbjct  473  WLEVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGG  531

Query  537  VEHAILHLMYSRFFNKVMRDAGLVYVDEPFANLLTQGMVL-------------------K  577
             EHA+LHL+Y+RF +KV+ D G+V   EPF +L+ QGM+L                   +
Sbjct  532  AEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKR  591

Query  578  DG---------------AKMSKSKGNIVSPEEIIEKYGADTARLFILFASPPEKDLEWSD  622
            DG               AKMSKS  N+V+P++++E+YGADT R++ +F +P +  + WS+
Sbjct  592  DGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSE  651

Query  623  QGVEGCHRFLQRVWRLVEELGPRVKDPVADERLDREVRRLVHKTIKKVTEDIEERFNFNT  682
            +G+EG ++FL+RV RL+          +++E     + ++ + T+K VTE++++  +FNT
Sbjct  652  EGLEGSRKFLDRVYRLI------TTKEITEEN-SGALDKVYNETVKAVTEQVDQ-MKFNT  703

Query  683  AISAIMEMVNALNSRKEESISGPVIKEALENLLVMLAPFAPHITEELWERL-GNKQSIHL  741
            AI+ +M  VNA  + KE+ + +   K     ++ ++APFAPH+ EELW+ L ++ +SI  
Sbjct  704  AIAQLMVFVNA--ANKEDKLFSDYAK----GFVQLIAPFAPHLGEELWQALTASGESISY  757

Query  742  MPWPevdeeamaeevvevviqvNGKVRGKLMLPAGVTEEEMKEAALSHDRVLPLLEGknv  801
            +PWP  DE  + E+ VE+V+Q++GKV++KL+++ +++ EE++E AL++++V + + GK++
Sbjct  758  VPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDI  817

Query  802  vkvvtvpkklvNIVVK  817
            +KV++VP+KLVNIV+K
Sbjct  818  IKVIAVPNKLVNIVIK  833

806) Theth_1781 in NC_015707


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  580 bits (2189),  Expect = 2e-166, Method: Compositional matrix adjust.
 Identities = 375/857 (44%), Positives = 542/857 (64%), Gaps = 73/857 (8%)

Query  4    YEPAEIEPKWQRYWEEKGFFKTPQYSEKPKYYMLVMFPYPSGT-LHVGHVKNYVIGDAVA  62
            Y+ + IEPKWQ +W ++  FKT   + KPK+Y L MFPYPSG+ LHVGH   Y   D ++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRMRGYNVLHPFGYDAFGLPAENAAIEKKIHPRDWTMANINTIRRQIKRLGISYDWDR  122
            R+KR +G NVLHP G DAFGLPAE+ A++   +P + T  NI  ++RQI+ LG+SYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EIITCNEDYYKWTQWIFLKLYEAGLAYKKMAPVNWCPKCMTSLANEQV-KDGACERCGTP  181
            E+ T + +YYKWTQWIF KLYE GLAY    PVNW     T++ANE+V  DG+ ER G P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VTVRHLEQWFFKITNYAERLLKDLDKLTGWPEHVKTMQRNWIGQSEGAKVAFKVDGLDLE  241
            V  + + QW +KIT YAERLL DL+ + +WPE +K MQRNWIG+S GA+V+FKV + D +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  242  IEVFTTRPDTIWGVTFMALAPESPLVEKIILPELREELDKFLVRIMSQDRFKRGAVEAEK  301
            + VFTTRPDT+ G T+  LAPE +LV+ I  ++  E +  +  +   +  + R  +  EK
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEK  302

Query  302  EGFFTGRYAINPVNGEKVPIYVANYVLMEYGTGAVMGVPAHDQRDYDFAKKYGIPIRQVI  361
             G  TG YAINPVNG  +P+ +A+YVL  YGTGA+M+VPAHD+RD +FAK++ + I  V+
Sbjct  303  TGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL  362

Query  362  KPAHEISLDKAYDGPGVMINSGELTGTVVPDEMEKVFRWLEEKGIGKKTVQYKLRDWLIS  421
              ++    + A+   G+ INS+ L G   +  + K+  WLE  G+G+  V Y+LRDWL+S
Sbjct  363  EGGN--VEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  422  RQRYWGAPIPIVYCEKCGMVPVPEKDLPVRLPYNVEFLP--TGQSPLMLSEEFKSTTCPK  479
            RQRYWG PIPI+  E     +VPE +LP+ LP   ++ P  TG+SPL    +    T   
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  480  CGGPALRDADTMDTFVDSSWYFLRYVNP----KLEDKPFLKEDVDYWLPVDQYVGGVEHA  535
             G  + R+++TM    +SSWY+LRY++P    KL D  +LK+    WLPVD YVGG EHA
Sbjct  481  -GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQ----WLPVDIYVGGAEHA  535

Query  536  ILHLLYSRFITKVLYDLGYISFDEPFTNLFTQGMIYKDGF--------------------  575
            +LHLLY+RF  KVLYDLG ++  EPF +LF QGMI   ++                    
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSF  595

Query  576  --------------KMSKSKGNVVSPDEMIEKYGADTLRLYILFMGPPEKDAEWSDAGIE  621
                          KMSKS  NVV+PD+++E+YGADTLR+Y +FMGP +    WS+ G+E
Sbjct  596  FHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLE  655

Query  622  GVYRFIKRSWNVISEIISLEETGTQEYSEREKQLLRKL-HSMLKKITEDMEGGFKFNTAI  680
            G  +F+ R   +I+         T+E +E +   L K+ +  +K +TE+++   KFNTAI
Sbjct  656  GSRKFLDRVYRLIT---------TKEITEENSGALDKVYNETVKAVTEQVD-QMKFNTAI  705

Query  681  SGLMELINAISDYMSEVPREKWNTKLLKECAEKFLLMISPFAPHFAEELWH-MMGKKESI  739
            + LM ++NA +           + KL+ + A  F+ +I+PFAPH++EELW+ + +  ESI
Sbjct  706  AQLMVFVNAANK----------EDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESI  755

Query  740  MLENWPQYDENALKVEEIEIAVQVNGKVRDKIKVPANADEELVKQLALSSERVRKFLNG-  798
                WP YDE+ L  +++EI VQ++GKV+ K+ V+ +   E ++++AL++E+V+  + G 
Sbjct  756  SYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGK  815

Query  799  EPKKIVYVKGRLLSITC  815
            +  K++ V  +L++I  
Sbjct  816  DIIKVIAVPNKLVNIVI  832

807) leuS in NC_008700


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  579 bits (2187),  Expect = 3e-166, Method: Compositional matrix adjust.
 Identities = 380/867 (44%), Positives = 571/867 (66%), Gaps = 49/867 (5%)

Query  10   YIHSEIEAEVQKYWADNKTFEVTEDPAKEKFYCLSMFPYPSGR-LHMGHVRNYTIGDVVA  68
            Y H+ IE+  Q +WADN TF    D++K KFY L MFPYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  69   RFQRLQGKNVLQPIGWDAFGLPAENAAIKNATAPAPWTYENIDYMKNQLKMLGFGYDWSR  128
            RF+R QG NVL+P+GWDAFGLPAE+ A+  +  PA  T ENI   K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  129  EIATCTPEYYRWEQWFFTKLYEKGLVYKKTSAVNWCPNDQTVLANEQV-QDGCCWRCDTP  187
            E+ T  P+YY+W QW+FTKLYEKGL Y    +VNW  +  T +ANE+V  DG   R + P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  188  VEQKEIPQWFIKITAYAEELLNDIDNLEGWPEQVKTMQRNWIGRSEGVEMTFKVKDSDDS  247
            V +K + QW +KITAYAE LL+D+++++ WPE +K MQRNWIG+S G ++TFKVKD+D  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  248  FDIYTTRPDTVMGVTYVAIAAGHPLAEKAALNNPELAAFVEECKQSGTSEAELA----TM  303
            F ++TTRPDT+ G TY  +A+ H+L +  A+  ++ A  V + K+ ++  ++LA    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVD--AITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  304  EKKGVATGLYAIHPLTGEEVPVWAANFVLMNYGTGAVMSVPAHDQRDYEFAKKYGLALKA  363
            EK GV TG YAI+P+ G E+PVW A++VL +YGTGA+M+VPAHD+RD EFAK++ L + +
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  364  VIKPADGEVDISEAAYTEKGVLFNSAEFDGLDFDGAFNAIADKLAAEGKGKRQVNFRLRD  423
            V+  +    ++ EAA+TE G+ +NS  +DGLD  +A+  + + L AEG G+ +V +RLRD
Sbjct  361  VLEGG----NVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  424  WGVSRQRYWGAPIPMVTLEDGTVMPTPEDQLPVILP--EDVVMDGV-QSPIKADKEWAK-  479
            W  SRQRYWG PIP++  EDGT  + PE +LP++LP   D+   G  +SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  480  TQVNGQDALRETDTFDTFMESSWYYARYCSPKANEML-DPAKANYWLPVDQYIGGIEHAC  538
            T+ +G  + RET+T      SSWYY RY  P   E L D    + WLPVD Y+GG EHA 
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  539  MHLLYFRFFHKLLRDAGLVNSNEPAKRLLTQGMVLADAFYYNNEKGARVWVSPLDVTVVE  598
            +HLLY RF HK+L D G+V ++EP ++L+ QGM+L+ +  Y + +GA V         VE
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS--YRDSRGALV-----ATDKVE  589

Query  599  KDDKGRILKAVDTEGHELVYTGMSKMSKSKNNGIDPQVMVEKYGADTVRLFMMFASPPEL  658
            K D G ++     E  E    + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P + 
Sbjct  590  KRD-GSFFHVETGEELE---QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  659  TLEWQESGVEGAHRFIKRLWKLASEYSAAPATEALDVSALNADQKTLRRELHKTIAKVTD  718
            ++ W E G+EG+++F+ R+ +L +         + +++  + +  +L +  + T+  VT+
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLIT---------TKEIT--EENSGALDKVYNETVKAVTE  694

Query  719  DLGRRQMFNTAVAAVMELMNHLQKAPLASAQDKALMNEALSAVVRLLYPIAPHVCFNLWR  778
            ++++ + FNTA+A +M ++N       A+ ++  L ++   + V+L+ P+APH+  +LW+
Sbjct  695  QVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  779  ELGNSG-AIEDAGWPATDESALVEDSKLIVVQVNGKVRAKLTVAADATKEQVEALGLAED  837
             L  SG +I    WP+ DES LVE+   IVVQ++GKV+AKL VA D ++E+++ ++LA++
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  838  AVRKYTDGVTVRKVIYVPGKLLNIVAN  864
             V+    G  + KVI VP KL+NIV +
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVIK  833

808) leuS in NC_010475


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  578 bits (2182),  Expect = 6e-166, Method: Compositional matrix adjust.
 Identities = 393/852 (47%), Positives = 567/852 (67%), Gaps = 29/852 (3%)

Query  5    YSAADIEAKWQQQWLELGLDKTPSQSDKPKFYALSMFPYPSGK-LHMGHVRNYVITDVIA  63
            Y  + IE+KWQ  W +    KT +++ KPKFYAL MFPYPSG  LH+GH   Y  TD+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYKRMQGYRVLHPMGWDAFGLPAENAAIDRGIPPAKWTYQNIAQMREQLKQLGLSIDWDR  123
            R+KR QG  VLHPMGWDAFGLPAE+ A+D G  PA  T +NIA+ + Q++ LG+S DWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVATCSPDYYKWTQWLFLQFYKAGLAYQKEAAVNWDPIDQTVLANEQVDAEGRSWRSGAI  183
            EV T  P+YYKWTQW+F ++Y  GLAY+ E +VNW     T +ANE+V ++G S R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  184  VEKKLLRQWFLKITDYAEELLQDLNTLDGWPERVKLMQENWIGKSTGAHLEFPVVGSDEK  243
            V +K +RQW LKIT YAE LL+DL+ +D WPE +K MQ NWIGKSTGA++ F V ++D  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  244  VAVFTTRLDTVFGVTYVVLAPEHPLVAQVTTPAQKAAVDAFIAEVSQESEQDRTADDKPK  303
             +VFTTR DT+FG TY VLAPEH+LV  +TT+ Q  AV  +  + S  S+  RT   K K
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEK  302

Query  304  KGVATGGMVTNPFTGEEVPILIANYVLYEYGTGAVMGVPAHDSRDCKFAKENNLPIKMVI  363
             GV TG+   NP  G E+P+ IA+YVL  YGTGA+M+VPAHD RD  FAK+ NL I  + 
Sbjct  303  TGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDI--IP  360

Query  364  IPEGGDATAVLTEAYTEAGIMVNSGQFDGLVSTEGKKAIAKFAAENGFGREQIQYRLRDW  423
            + EGG+       A+TE G+ +NS+ +DGL  + +   +      +G G E++ YRLRDW
Sbjct  361  VLEGGNVEEA---AFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDW  417

Query  424  LISRQRYWGCPIPMIYCDDCGvvpvpdsdlpvvlpedvEF--SARGGSPLAQMADWQAVD  481
            L+SRQRYWG PIP+I  +D    +VP+S+LP+VLP   ++  S+ G SPLA+++DW  V 
Sbjct  418  LFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT  477

Query  482  CPCCGKAARRETDTMDTFIDSSWYFLRYTDANNTEKPFALDPVNDWMAVDQYVGGIEHAI  541
                 K +RRET+TM    +SSWY+LRY D++NTEK    + +++W++VD YVGG EHA+
Sbjct  478  REDGVK-GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  542  LHLLYSRFFTKVVRDRQLVSVDEPFKRLLTQGMVQALTYKNPRTNKYVPADQVDPNDPK-  600
            LHLLY+RF  KV+ D  +V+  EPF++L+ QGM+ + +Y+++R    V++D+V+  D   
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGA-LVATDKVEKRDGSF  595

Query  601  -DPETGEPLTGFYEKMSKSKYNGVDPALVLDKYGADTARMFILFKAPPEKDLEWDDADVE  659
             + ETGE L     KMSKS  N V+P  V+++YGADT R++ +F +P +  + W + ++E
Sbjct  596  FHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLE  655

Query  660  GQFRFLNRIWNLVAGYEAAETSVKATGELSKAEKDLRRAVHTAIKEIQEDLEGDYQFNTA  719
            G  +FL+R+  L++   + E +   +G L K  ++  +AV   + ++        +FNTA
Sbjct  656  GSRKFLDRVYRLIT---TKEITEENSGALDKVYNETVKAVTEQVDQM--------KFNTA  704

Query  720  IAELMKLNNAIKDVKCVDSPVYKEAIETLILLLAPFAPHIADELWSNL-GHSESIHTVPF  778
            IA+LM + NA +     +  ++ +    ++ L+APFAPH+++ELW  L + +ESI  VP 
Sbjct  705  IAQLMVFVNAANK----EDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPW  760

Query  779  PQLDETALTVDEITIVIQILGKTRGTIQVPAGISKADLEKTATASDIAQRYIAGKEIKKV  838
            P  DE+ L  +++ IV+QI GK ++ + V+ ++S+ +L+  A A++  Q  IAGK+I KV
Sbjct  761  PSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKV  820

Query  839  IVVPNKLVNFVI  850
            I VPNKLVN+VI
Sbjct  821  IAVPNKLVNIVI  832

809) Desgi_3363 in NC_021184


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  578 bits (2182),  Expect = 6e-166, Method: Compositional matrix adjust.
 Identities = 355/839 (43%), Positives = 547/839 (66%), Gaps = 73/839 (8%)

Query  5    YEFKVIEAKWQQKWSEQDIYAVPDFSDRPKYYCLEMFPYPSGK-LHMGHVRNYSIGDVVA  63
            Y+   IE+KWQ  W++++ +     + +PK+Y L+MFPYPSG  LH+GH   Y+  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RFKTMQGFNVLHPMGWDAFGLPAENAAIKHGALHPAQWTTDNIDSMREQLKQLGISYDWS  123
            RFK  QG NVLHPMGWDAFGLPAE+ A+  G  +PA+ T++NI + + Q++ LG+SYDW 
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGN-DPAEFTAENIANFKRQINALGFSYDWD  122

Query  124  REVATCHPGYYKWTQWLFLQLYHHGLAYKKKSAVNWCPSCATVLANEQV-KEGSCERCAS  182
            REV T +P YYKWTQW+F +LY+ GLAY    +VNW    +T +ANE+V  +G+ ER + 
Sbjct  123  REVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGY  182

Query  183  VVEKRELEQWFFKITQYADRLLADLDKLGGWPDKVKIMQENWIGRSEGAEITFQIDGIDE  242
             V ++ + QW +KIT YA+RLL DL+ ++ WP+ +K MQ NWIG+S GA++TF++ + D 
Sbjct  183  PVVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDK  241

Query  243  TITVFTTRPDTVYGVTYMVLAPEHPLVEKLIEGKPQAGEIRDFVHKVRNLSELARTSTEA  302
             +TVFTTRPDT++G TY VLAPEH+LV+ +  +  QA  + D+ ++    S+LART    
Sbjct  242  DFTVFTTRPDTLFGATYAVLAPEHALVDAITTSD-QAEAVADYKRQASLKSDLARTDLAK  300

Query  303  EKIGLLTGAHCINPVNGEKVPILVANYVLLEYGTGAVMGVPAHDQRDFEFARKYNLPIRV  362
            EK G+ TG+  INPVNG  +P+ +A+YVL  YGTGA+M+VPAHD+RD EFA+++NL I  
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  363  VIQPEGVTLDPAVMTEAYDGEGLMVNSGPFNGTPNREGITAVIKYLQEQKLGDGRINYRL  422
            V++   V         A+  +GL +NS+ ++G  +  +I+ ++  L+ + +G+  + YRL
Sbjct  361  VLEGGNVE------EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRL  414

Query  423  RDWLISRQRYWGAPIPIIYCDKCGVVPVPDKDLPVMLPMDVAFKP--TGRSPLEEHADFV  480
            RDWL+SRQRYWG PIPII  +     +VP+ +LP++LP+   ++P  TG SPL + +D +
Sbjct  415  RDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWL  474

Query  481  NTTCPTCGGPARRETDTMDTFMCSSWYYYRYTSPRDDANAWDYDKVRRWLPVDQYIGGVE  540
            + T    G  +RRET+TM     SSWYY RY  P++  +  D + +++WLPVD Y+GG E
Sbjct  475  EVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAE  533

Query  541  HAILHLLYSRFFTKVLYDLKLVDNDEPFTNLLTQGMVL-------------------KDG  581
            HA+LHLLY+RF  KVLYDL +V   EPF +L+ QGM+L                   +DG
Sbjct  534  HAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDG  593

Query  582  ---------------AKMSKSKGNVVSPEDIVATYGADTARLFILFASPPERDLEWSDQG  626
                           AKMSKS  NVV+P+D+V  YGADT R++ +F +P +  + WS++G
Sbjct  594  SFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEG  653

Query  627  VEGCYRFLNRVWRLVAPLGDMLATGVVAAQTGANPVGVNKDMRRMIHLAIKKVTEDVGNR  686
            +EG  +FL+RV RL++      +  +   ++GA        + ++ + ++K VTE+V ++
Sbjct  654  LEGSRKFLDRVYRLIT------TKEITEENSGA--------LDKVYNETVKAVTEQV-DQ  698

Query  687  FNFNTAVSAIMELVNAMYQYRELPECDRDAGvlreavealllllaPFAPHITEELWN-LT  745
             +FNTA++ +M +VNA          +++  ++ +   +++ L+APFAPH+ EELW+ LT
Sbjct  699  MKFNTAIAQLMVFVNA---------ANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALT  749

Query  746  GHEGIIHAQPWPQYDPEAIIEDEITIVVQINGKVRDRMLVPADIKPDAMRELVMQQEKV  804
            +    I   PWP YD   ++E+++ IVVQI+GKV+ +++V+ D+  + ++E+ + +EKV
Sbjct  750  ASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKV  808

810) leuS in NC_012658


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  578 bits (2181),  Expect = 7e-166, Method: Compositional matrix adjust.
 Identities = 381/847 (45%), Positives = 545/847 (65%), Gaps = 59/847 (6%)

Query  6    TKIDEKWQKKWEESSLYKFNNENLDKKLYVLEMFSYPSGSKLHAGHWFNYGPVDSWARFK  65
            T I+ KWQ  W ++  +K   +    K+Y L+MF+YPSG+ LH GH   Y + D  +RFK
Sbjct  7    TAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSRFK  66

Query  66   RMQGYNVFQPMGFDAFGLPAENYAIKTGIHPKDSTFKNIETMETQLKAMGAMFNWENEVI  125
            R QG NV++PMG DAFGLPAE+YA+ TG +P + T  NI     Q++A+G  ++W+ EV 
Sbjct  67   RAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDREVN  126

Query  126  TCSPDYYKWTQWVFLKLYEKGLAYKKKAPVNWCPSCNTVLANEQVL-DGKCERCDSNVDK  184
            T  P+YYKWTQW+F KLYEKGLAY    PVNW     T +ANE+VL DG  ER +  V +
Sbjct  127  TTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVR  186

Query  185  KNLEQWFLKITDYAdellekldeldWPEKTKAMQKHWIGKSVGAEVTFNVADSDLSFNVF  244
            K + QW LKIT YA+ LLE L+E+DWPE  K MQ++WIGKS GA+VTF+V D+D  F VF
Sbjct  187  KPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVF  246

Query  245  TTRVDTLFGVTYVVLAPENDLVDKLTTPENKAEVESYKTQAKNQSDIERQSITREKTGVF  304
            TTR DTLFG TY VLAPE+ LVD +TT+++   V  YK QA  +SD+ R  +++EKTGV 
Sbjct  247  TTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVW  306

Query  305  SGSYAINPINGKKVPIWIGDYVLNTYGTGCVMAVPAHDERDFAFATKYNLHIERVIEGG-  363
            +GSYAINP+NGK +P+WI+DYVL +YGTG +MAVPAHDERD  FA ++NL+I  V+EGG 
Sbjct  307  TGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGN  366

Query  364  -DSLPYTEYGKMVNSGEFDGLFGNKAKEAVISKLESMNLGRKKINYRLRDWLVSRQRYWG  422
             +  ++TE G  +NS+ +DGL    A   ++  LE+  +G  ++ YRLRDWL SRQRYWG
Sbjct  367  VEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWG  426

Query  423  APIPIIYCEKCGTVEVPIEQLPVELPYNVEFSPDGK--SPLGKCDDFINTTCPKCGGPAK  480
             PIPII  E   +  VP  +LP+ LP   ++ P G   SPL++  D ++ T    G  ++
Sbjct  427  EPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED-GVKGR  485

Query  481  READTLDTFVCSSWYYLRYPDNNNGKDAFNPELINKMLPVDKYVGGPEHACMHLLYARFI  540
            RE++T+     SSWYYLRY D +N     + EL+++ LPVD YVGG+EHA +HLLYARF 
Sbjct  486  RETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFW  545

Query  541  TKALRDMGYLNFDEPFLSLTHQGLILGP----------------------------DGL-  571
             K L D+G +   EPF  L +QG+ILG                             + L 
Sbjct  546  HKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEELE  605

Query  572  ----KMSKSKGNTISPDDYIREFGSDVFRMYLMFGFDYTEGGAWSDDAIKSIGRFVDRVE  627
                KMSKS  N ++PDD + ++G+D +R+Y MF      + AWS++++ +  +F+DRV 
Sbjct  606  QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVY  665

Query  628  RILENAREEIKNSKDNKSTMDKDEKELNYVRHHSIKSITEDIDKMQFNTSIARLMEFTNA  687
            R++             K   + +   L+ V ++++K++TE++D+M+FNT+IA+LM F NA
Sbjct  666  RLI-----------TTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNA  714

Query  688  ISKYLGNDTIKNSSFLKEGIIDFIRLLAPFAPHFAEEQWE-LIGINSSVFNEKWPKFDPK  746
             +        K+  ++ +   +F++L+APFAPH++EE W+ L +   S+    WP +D  
Sbjct  715  AN--------KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDES  766

Query  747  ALIKDEVEIAVQVNGKIRAKinistssseeeikesALNNEDIKNSIGDKEIKKVIVIKNR  806
             L+ ++VEI VQ++GK++AK+ ++   S EE++E AL NE ++  I++K+I KVI + N+
Sbjct  767  KLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNK  826

Query  807  LVNIVAK  813
            LVNIV K
Sbjct  827  LVNIVIK  833

811) leuS in NC_009617


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  576 bits (2174),  Expect = 2e-165, Method: Compositional matrix adjust.
 Identities = 380/848 (45%), Positives = 556/848 (66%), Gaps = 58/848 (6%)

Query  6    TKIDEKWQKFWDENEVYKFNPENSGKKLYTLEMFSYPSGAQLHAGHWFNYGPTDSWARLK  65
            T I+ KWQ FW +N+ +K   + S  K+Y+L+MF+YPSGA LH GH   Y +TD  +R+K
Sbjct  7    TAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSRFK  66

Query  66   RMQGYNVFQPMGFDAFGLPAENYAIKTGIHPQDSTLKNIETMEKQLKSMGAMFNWENEVV  125
            R QG NV++PMG DAFGLPAE+YA+ TG +P + T  NI    +Q++++G  ++W+ EV 
Sbjct  67   RAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDREVN  126

Query  126  TCLPDYYKWTQWLFLKLYEKGLAYRKKAPVNWCPSCNTVLANEQVV-DGVCERCSTEVTK  184
            T  P+YYKWTQW+F KLYEKGLAY    PVNW     T +ANE+V+ DG  ER +  V +
Sbjct  127  TTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVR  186

Query  185  KDLTQWFFKITEYgdelldkldgldWPEKTKSMQKHWIGRSYGAEVTFKVKDSDLKFDVF  244
            K + QW +KIT Y++ LL+ L+ +DWPE  K MQ++WIG+S GA+VTFKVKD+D  F VF
Sbjct  187  KPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVF  246

Query  245  TTRVDTLNGVTYVVLAPENKLVDELTIPeykaaveeykeaaakQSEIERQSVSKEKTGVF  304
            TTR DTL G TY VLAPE+ LVD +T ++   AV +YK  A+ +S++ R  ++KEKTGV 
Sbjct  247  TTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVW  306

Query  305  TGSYAINPINGKVVPIWISDYVLATYGTGCVMAVPAHDERDFAFATKFNLPIERVITDKE  364
            TGSYAINP+NGK +P+WI+DYVLA+YGTG +MAVPAHDERD  FA +FNL I  V+ + +
Sbjct  307  TGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGN  366

Query  365  NTNPDLPYCEYGVLVNSGKFDGLTTDEAKKKIVEELEKDELGAMKKNFRLRDWLVSRQRY  424
              ++  ++ E G+ +NS+ +DGL    A  K+VE LE + +G  +  +RLRDWL SRQRY
Sbjct  367  VEEA--AFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRY  424

Query  425  WGAPIPVIYCDDCGIVPVPEKDLPVKLPYNVEFTPDGK--SPLGKCEDFVNTTCPHCGKP  482
            WG PIP+I  +D    +VPE +LP+ LP   ++ P G   SPL++  D ++ T  +  K 
Sbjct  425  WGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK-  483

Query  483  AKREADTLDTFVCSSFYYLRYVDNKNDDAPFDSEKVNKMLPVDKYVGGPEHACMHLLYAR  542
            ++RE++T+     SS YYLRY+D  N +   D E +++ LPVD YVGG+EHA +HLLYAR
Sbjct  484  GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYAR  543

Query  543  FITKALRDMGYLNFDEPFLSLTHQGLILGP----------------------------DG  574
            F  K L D+G +   EPF  L +QG+ILG                             + 
Sbjct  544  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEE  603

Query  575  L-----KMSKSKGNTISPDDYIKEYGADVFRMYLMFGFGYTEGGAWSDDGIKSVGKFVDR  629
            L     KMSKS  N ++PDD + +YGAD +R+Y MF      + AWS++G+ +  KF+DR
Sbjct  604  LEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR  663

Query  630  IERILENCRNIINSNESTKDSIDSAEKELNFWKHNTIKGVTEDGDKMQFNTAIARLMELT  689
            + R++   ++I + N ++ D +        +  ++T+K+VTE+ D+M+FNTAIA+LM   
Sbjct  664  VYRLI-TTKEITEENSGALDKV--------Y--NETVKAVTEQVDQMKFNTAIAQLMV--  710

Query  690  NALNKYTQENIKNANFLKETIVDFIKLLAPFAPHFAEEQW-SLLGNNSTIFNEKWPEFNP  748
                 + +   K+ +++ +   +F++L+APFAPH++EE W +L ++  +I    WP ++ 
Sbjct  711  -----FVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDE  765

Query  749  AALVKDEVEIAIQINGKIKAKIMVASNLDEEGIKAASLENETIKENTEGKTIVKVIVIKG  808
            + LV ++VEI +QI+GK+KAK++VA +L  E ++  +L NE ++ +  GK I+KVI +  
Sbjct  766  SKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPN  825

Query  809  RLVNIVVK  816
            +LVNIV+K
Sbjct  826  KLVNIVIK  833

812) leuS in NC_007335


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  576 bits (2175),  Expect = 2e-165, Method: Compositional matrix adjust.
 Identities = 348/859 (41%), Positives = 568/859 (67%), Gaps = 39/859 (4%)

Query  13   YEPREVEAYWQKEWASDDLYRTNTEVNKENTFYALSMFPYPSG-SLHMGHVRNYVITDVL  71
            Y+   +E+ WQ  WA ++ ++T T+ +K + FYAL MFPYPSG +LH+GH   Y  TD+L
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPK-FYALDMFPYPSGAGLHVGHPEGYTATDIL  62

Query  72   ARYKRMKGFNVLHPMGWDSFGLPAENAAIEREISPSTWTDKNISQMKDQLDRLGLSIDWS  131
            +R+KR +G NVLHPMGWD+FGLPAE+ A++    P+  T  NI++ K Q++ LG+S DW 
Sbjct  63   SRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWD  122

Query  132  KEVTTCKEEYYKWTQYIFNQLHKNNLAYQKKATVNWDPIDQTVLANEQVDAEGKSWRSGA  191
            +EV T   +YYKWTQ IF +L  + LAY+    VNW     T +ANE+V ++G S R+G 
Sbjct  123  REVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGY  182

Query  192  KVEKKELNQWFLRITSFAEDLNKDLIKLNDWPDRVRVMQKNWIGKSIGAEITFEIKNSDQ  251
             V +K + QW L+IT++AE L  DL  + DWP+ ++ MQ+NWIGKS GA++TF +K++D+
Sbjct  183  PVVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDK  241

Query  252  KITAFTTRIDTVYGVSYLVLASNHPLIDQLISSNDIDKLNDFRQTQEKLSDLERNSDTRQ  311
             +T FTTR DT++G +Y VLA++H+L+D + +S++ + + D+++     SDL R   +++
Sbjct  242  DFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKE  301

Query  312  KLGMYLGVDAINPANNKEIPIWIGDYVIMEYGTGAVMGVPAHDSRDYQFAKSYDLPIQYV  371
            K G+  G  AINP N KE+P+WI+DYV+  YGTGA+M+VPAHD RD +FAK ++L I  V
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  372  IKPNIDEDESYLNAEFVDKGIMINSDKFNGIESDIAKTQILEFGSNSNWAKPKITYKLRD  431
            +     E+     A F + G+ INSD ++G++   A ++++E       ++ ++TY+LRD
Sbjct  362  LEGGNVEE-----AAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  432  WLISRQRYWGCPIPIINCKKCGQVRVPDNDLPVVLPI--DIKLTGKGKSPLTTKTEWINT  489
            WL+SRQRYWG PIPII+        VP+++LP+VLP+  DI+ +G G SPL+  T+W++ 
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  490  CCPKCGTEAKRETDTMDTFMCSSWYFLRYINPDNCEKPFLKSEIDKWLPVKQYVGGIEHA  549
                 G  ++RET+TM     SSWY+LRYI+P+N EK      + +WLPV  YVGG EHA
Sbjct  477  TRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  550  ILHLLYSRFLTKALKKCGLINIDEPFKKLLTQGMVQAVTFKNPNTNKYFSKDQIKDIDNP  609
            +LHLLY+RF  K L   G++   EPF+KL+ QGM+ + +++++      + D++   D +
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGA-LVATDKVEKRDGS  594

Query  610  -KDPLTGENIEIIYEKMSKSKYNGVDPSVVIDKYGADTARMFILFKAPPEKDLEWDDSDV  668
              +  TGE++E    KMSKS  N V+P  V+++YGADT R++ +F +P +  + W + ++
Sbjct  595  FFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGL  654

Query  669  EGQYRFIQRLWKFVINTFKLTNNNSRSNIEKEKSKDEEALRLINIAIKEITDDLDNLQFN  728
            EG  +F++R+ +++    K   +++ + ++K          + N ++K +T+++D+++FN
Sbjct  655  EGSRKFLDRVYRLITT--KEITEENSGALDK----------VYNETVKAVTEQVDQMKFN  702

Query  729  TAISELMKVVNGLS----LIVNYCSNETLNKVISILVKITSPFSPHIAEELWKTI-GNTQ  783
            TAI++LM  VN+ +    L+ +Y            +V++ +PF+PH++EELW+++ ++ +
Sbjct  703  TAIAQLMVFVNAANKEDKLFSDYAKG---------FVQLIAPFAPHLGEELWQALTASGE  753

Query  784  SIHLQSWPEFDAGAIEQDTFKLMIQINGKVRGSINASKNLSKENLEDLAIKTEAAIKWMD  843
            SI   +WP +D + + ++   +++QI+GKV++ +  +K+LS+E+L+++A+  E     + 
Sbjct  754  SISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIA  813

Query  844  GKEPKRIIVVPNKLVNIVI  862
            GK+  ++I VPNKLVNIVI
Sbjct  814  GKDIIKVIAVPNKLVNIVI  832

813) leuS in NC_009253


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  575 bits (2173),  Expect = 3e-165, Method: Compositional matrix adjust.
 Identities = 372/864 (44%), Positives = 568/864 (66%), Gaps = 75/864 (8%)

Query  5    YDFKEIEKKWQEDWNKENTYQVPDFSERPKYYCLEMFPYPSGK-LHMGHVRNYSIGDVVA  63
            YD   IE KWQ  W  ++T++    + +PK+Y L+MFPYPSG  LH+GH   Y+  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RFKTMQGYDVLHPMGWDAFGLPAENAAIKHGIAPATWTWDNIAHMRSQLKQLGLSYDWNR  123
            RFK  QG +VLHPMGWDAFGLPAE+ A+  G  PA  T +NIA+ + Q++ LG+SYDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVATCHTEYYKWGQWLFLQLYKKGLCYKKHARVNWCPDCATVLANEQVV-DGACERCSAV  182
            EV T + +YYKW QW+F +LY KGL Y  +  VNW  + +T +ANE+V+ DG+ ER +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VEQKELDQWFFRITEYAQRLLNDLKLLKGWPDKVKIMQENWIGRSEGAELTFQVEGSDES  242
            V +K + QW ++IT YA+RLL+DL  + +WP+ +K MQ NWIG+S GA++TF+V ++D  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  ITVFTTRPDTVYGVSYMVLAPEHPLVAKLIAGRPQEAEVIGFVNRVNKLTELDRT--SSD  300
            +TVFTTRPDT++G +Y VLAPEH+LV   I+   Q   V ++  + +  ++L RT  + +
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDA-ITTSDQAEAVADYKRQASLKSDLARTDLAKE  301

Query  301  KEGVFTGAYCINPFDGARVPILIANYVLYHYGTGAVMGVPAHDERDFEFAHKYNLPIKVV  360
            K GV TG+Y INP +G  +P+ IA+YVL  YGTGA+M+VPAHDERD EFA ++NL I  V
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  361  IYPAQDKEIRVEDMKEAYTADGIMVHSGPFDGSPNRQGIKKVIKYAEEKGIGKGIVNYRL  420
            +  ++  E        A+T DG+ ++S+ +DG  +  +I K++   E  G+G+  V YRL
Sbjct  362  LEGGNVEE-------AAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRL  414

Query  421  RDWLISRQRYWGTPIPIVYCEKCGTVPVPEDQLPVILPTDVAFKP--TGESPLKGRPDFV  478
            RDWL+SRQRYWG PIPI+  E   + +VPE +LP++LP    ++P  TGESPL    D +
Sbjct  415  RDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWL  474

Query  479  HTTCPQCGGPAQRETDTMDTFVDSSWYYLRYTSSRDTEYAWDKNKADRWMNVDQYIGGVE  538
            + T  + G  ++RET+TM    +SSWYYLRY  +++TE   D +   +W+ VD Y+GG E
Sbjct  475  EVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAE  533

Query  539  HAILHLLYSRFFTKVFYDLGLVNVQEPFENLLTQGMVL-------------------KDG  579
            HA+LHLLY+RF  KV+YDLG+V  +EPF++L+ QGM+L                   +DG
Sbjct  534  HAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDG  593

Query  580  S---------------KMSKSKGNVVSPEEIIDRYGADTARMFILFAAPPERDLEWSDRG  624
            S               KMSKS  NVV+P++++++YGADT R++ +F +P +  + WS+ G
Sbjct  594  SFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEG  653

Query  625  VEGSHRFLNRVWRLVYSLKDEVAGAPAISSVNAYVGVHKEMRRLTHYAIKKVTEDVSGRF  684
            +EGS++FL+RV RL+ +   E++   + +  + Y             ++K VTE+V ++ 
Sbjct  654  LEGSRKFLDRVYRLITT--KEITEENSGALDKVYNE-----------TVKAVTEQV-DQM  699

Query  685  NFNTAISTIMELVNGIYTYRDKVAAVERDTAVLAEAVNSTIILLAPFAPHIAEELWSA-T  743
            +FNTAI+ +M +VN          A +++  ++++  ++ + L+APFAPH++EELW A T
Sbjct  700  KFNTAIAQLMVFVN----------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALT  749

Query  744  GHQGSVHKQPWLTFDSaalvedevevavQINGKVRERLNIPANMKPAEMQQYLMDMESVK  803
            +   S+   PW ++D + LVE++VE+ VQI+GKV+ +L ++ ++   E+Q+  +  E V+
Sbjct  750  ASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQ  809

Query  804  ILIGDKQIVKIIPVPGKLLNIVVK  827
              I++K+I+K+I+VP KL+NIV+K
Sbjct  810  AEIAGKDIIKVIAVPNKLVNIVIK  833

814) Ilyop_0169 in NC_014632


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  575 bits (2172),  Expect = 4e-165, Method: Compositional matrix adjust.
 Identities = 367/875 (42%), Positives = 560/875 (64%), Gaps = 54/875 (6%)

Query  4    YDFKSIESKWQEKWKQDNIFKSDNKVEGKENYYVLEMLPYPSGK-LHMGHVRNYTIGDVI  62
            YD  +IE+KWQ  W +++ FK++    +K ++Y L+M+PYPSG  LH+GH   YT  D++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDA-SKPKFYALDMFPYPSGAGLHVGHPEGYTATDIL  62

Query  63   ARYKKMKGYNVLHPMGWDSFGLPAENAAIQNGAHPAVWTKSNIENMTTQLKSLGFSYDWD  122
            +R+K+ +G NVLHPMGWD+FGLPAE+ A++ G +PA  T  NI N   Q+++LGFSYDWD
Sbjct  63   SRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWD  122

Query  123  REIASYRDDYYRWNQWIFKRMYEKGLVYKKKSSVNWCPDCQTVLANEQV-EDGKCWRHSK  181
            RE+ +   +YY+W QWIF ++YEKGL Y    +VNW  +  T +ANE+V  DG    ++ 
Sbjct  123  REVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTS-ERGG  181

Query  182  TDVIQKELEQWYFKITNYADELLEGHKELKGGWPEKVITMQKNWIGKSYGTEVNFKVVEN  241
              V++K + QW +KIT YA+ LLE+  E+  +WPE +  MQ+NWIGKS G++V FKV + 
Sbjct  182  YPVVRKPMRQWMLKITAYAERLLEDLEEV--DWPESIKDMQRNWIGKSTGANVTFKVKDT  239

Query  242  GEDLSVFTTRVDTLCGVTYCVIAPEHPMVNEIIKSNP--SIKEAVSAMTTEDVINRTAEG  299
            + D++VFTTR DTL G TY V+APEH++V+ I  S+   ++ +     +    + RT  +
Sbjct  240  DKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA  299

Query  300  KEKNGVFTGWHVINPANNEKVQLWIGDYVLMGYGTGAVMAVPCHDERDLMFAKKYDLPLR  359
            KEK GV TG   INP N   + +WI+DYVL +YGTGA+MAVP HDERD  FAK+++L + 
Sbjct  300  KEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDII  359

Query  360  VVINPVNKKTKEEVILKEDEMTEAFTDYGIITNSGEFNGLSSKEALVKIAEYLEEKKCGK  419
             V++  N                AFT+ G+  NS+ ++GL    A+ K+ E LE    G+
Sbjct  360  PVLEGGNVE------------EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGN  407

Query  420  RTINYRLKDWGVSRQRYWGTPIPALYCEKCGTVMEKDENLPVKLPG--DVIFSGNGN-PI  476
              + YRL+DW  SRQRYWG PIP +  E   +    + +LP+ LP   D+  SG G+ P+
Sbjct  408  ENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPL  467

Query  477  ETSEEFKNAVCPECGGKAKRETDTMDTFVDSSWYFLRYCDPKNTDLPFDKDIADGWFPVD  536
                +  + V  E G K++RET+TM    +SSWY+LRY DP NT+   D ++   W+PVD
Sbjct  468  ANVTDWLE-VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVD  526

Query  537  QYIGGVEHAVMHLLYARFFHKVLRDLGLLSTNEPFKRLLTQGMVLGPSYFSANENRYLYS  596
             Y+GG EHAV+HLLYARF HKVL DLG+++T+EPF++L+ QGM+LG SY   +    + +
Sbjct  527  IYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-RDSRGALVAT  585

Query  597  EEVEISGDKVLAKTTGEELVVKVEKMSKSKNNGVDPENIVATYGADTARLFTMFASPPEK  656
            + VE  ++  +   TGEEL     KMSKS +N V+P+++V  YGADT R++ MF +P + 
Sbjct  586  DKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  657  ELEWNENGLAGSYRFLNRVWRMVSESKAFFEAGSINLENLNKADKAILRKLHQTIKKVTE  716
             + W+E+GL GS +FL+RV R+++ +K + E  S  L+++           ++T+K VTE
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLIT-TKEITEENSGALDKV----------YNETVKAVTE  694

Query  717  SIENDYHFNTSIASNMELINELQDYKVNVLEKGDITSESKKLFTEAVNKMVIMLSPFVPH  776
             ++ +  FNT+IA  M ++N               ++   KLF++  +  V +++PF PH
Sbjct  695  QVD-QMKFNTAIAQLMVFVNA--------------ANKEDKLFSDYAKGFVQLIAPFAPH  739

Query  777  ICDELWSEL--GNEGFLFEEKWPEHVEELTVSDEVSIAVQVNGKVRGAVQVTRGTSKDEL  834
            + +ELW  L  + E++ +   WP   E   V ++V I VQ++GKV++ + V+++ S++EL
Sbjct  740  LGEELWQALTASGESISYVP-WPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREEL  798

Query  835  EKMALEMENVKKHIQDKNIVKMIIIPEKIVNIVVK  869
            + +AL  E+V+ +I +K+I+K+I +P+K+VNIV+K
Sbjct  799  QEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

815) Acfer_0634 in NC_013740


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  575 bits (2172),  Expect = 4e-165, Method: Compositional matrix adjust.
 Identities = 352/863 (41%), Positives = 551/863 (64%), Gaps = 72/863 (8%)

Query  6    YEPHEIEARWQQYWEDNKTYQVSNEDPRPKSYVLEMFPYPSG-NLHMGHVRNYSIGDVVA  64
            Y+   IE++WQ +W DN T++ + + ++PK Y L+MFPYPSG  LH+GH   Y+  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  65   RFRTMRGFNVLHPIGFDSFGMPAENAAIKHKIPPAKWTMENIANMTRQLKELGLSYDWDR  124
            RF+  +G NVLHP+G D+FG+PAE+ A+     PA  T ENIAN  RQ++ LG+SYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  125  KVVTCQEDYYKWTQWFFELMYKRGLAVKKEASVNWCDTCGTVLANEQV-EDGKCWRCHQP  183
             V T + +YYKWTQW+F  +Y +GLA   E +VNW +  GT +ANE+V  DG   R   P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  184  VEKKQLSQWFFKITDYAEQLLDDLAKLPGWPDRVKTMQKNWIGRSEGLEFGFDVPSLHKK  243
            V +K + QW +KIT YAE+LL+DL  + +WP+ +K MQ+NWIG+S G +  F V   +K 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  244  LMVYTTRPDTIYGVTFVVIPPEHPMVEELLKDNPRKAELEAFCNKVKNTSDIERTSSESE  303
            + V+TTRPDT++G T+ V++PEH++V+ +   +   A +  +  +    SD+ RT    E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEA-VADYKRQASLKSDLARTDLAKE  301

Query  304  KLGMYTGVDCIHPLTGEKVQIWITNYVLVDYGTGAVMGVPTGDHRDWLFATKYGIKKILT  363
            K G+ TG   I+P+ G  + +WI++YVL  YGTGA+M+VP+ D+RDW FA ++ +  I  
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  364  LQPKDKELKLEEMTDAYEDKDGVLVNAGPFTGMEMHKAMKAIIDYMEEKGLGKRRVNYRL  423
            L+  + E        A+ + DG+ +N++ + G++   A+  +++ +E  G+G+  V YRL
Sbjct  362  LEGGNVE------EAAFTE-DGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRL  414

Query  424  RDWLISRQRYWGCPIPVVYCPHCGEVLVPEKDLPVKLPL--DVKFDAGASSPLATSEQFV  481
            RDWL+SRQRYWG PIP++   +     VPE +LP+ LP+  D++  + + SPLA   + +
Sbjct  415  RDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWL  474

Query  482  NCTCPKCGGPAKRELDTMDTFLCSSWYYMRYTDPHNDKAPFSEEAVNHWMPVDQYIGGIE  541
            + T    G  ++RE +TM     SSWYY+RY DPHN      EE +++W+PVD Y+GG E
Sbjct  475  EVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAE  533

Query  542  HAILHLLYSRFFMKVLHDAGLVKADEPFTNLLTQGMVI-------------------KDG  582
            HA+LHLLY+RF  KVL D G+V + EPF +L+ QGM++                   +DG
Sbjct  534  HAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDG  593

Query  583  ---------------AKMSKSLGNVVSPEEIVGKFGADTARLFIMFAAPVERELEWSDQG  627
                           AKMSKSL NVV+P+++V ++GADT R++ MF +P++  + WS++G
Sbjct  594  SFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEG  653

Query  628  VEGSFRFLNRVWRIVYHFKDVLAKKATSYDTAHLNEADEELRHILHVSVKKVTEDIDQRF  687
            +EGS +FL+RV      ++ + +K  T       +E    L  + + +VK VTE++DQ  
Sbjct  654  LEGSRKFLDRV------YRLITTKEIT-------EENSGALDKVYNETVKAVTEQVDQ-M  699

Query  688  NFNTAISTLMELVNALYAYREKAEPVNDGLVYEAISK-LLLMLAPFTPHITEELWHDAMG  746
            +FNTAI+ LM +VNA         + +++ ++   +K ++ ++APF+PH+ EELW+   +
Sbjct  700  KFNTAIAQLMVFVNA---------ANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTA  750

Query  747  SETSIHKESWPTYDPEAIKVEQVEVLIQVNGKPKARIMAAPEMSKEDLGNLALEQAEVKA  806
            S  SI   +WP+YD   +  ++VE+++Q++GK KA+++ A ++S+E+L ++AL +  V+A
Sbjct  751  SGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQA  810

Query  807  AIGDKKVMKVIAVPGRLVNIVAK  829
             I++K ++KVIAVP +LVNIV K
Sbjct  811  EIAGKDIIKVIAVPNKLVNIVIK  833

816) Anamo_0594 in NC_018024


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  575 bits (2170),  Expect = 5e-165, Method: Compositional matrix adjust.
 Identities = 363/860 (43%), Positives = 551/860 (65%), Gaps = 70/860 (8%)

Query  3    YDFAAIEAKWQERWEKEGTFNVSPDEGKQKFYCLEMFPYPSGT-LHMGHLRNYSIGDLMA  61
            YD +AIE+KWQ  W  + TF+ + D +K KFY L+MFPYPSG+ LH+GH   Y+  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  62   RFLSMRGYNVLHPMGFDAFGLPAENAAIKYGVHPYEWTWKNIEKMTEQLRSMGCSYDWRR  121
            RF   +G NVLHPMG DAFGLPAE+ A+  G +P E T  NI +   Q+ ++G SYDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  122  RIATCHPSYYRWNQWFFLKFFERGLAYRAEAPINWCPGCKTVLANEQVIEGGHCWRCGSE  181
             + T +P+YY+W QW+F K++E+GLAY AE P+NW     T +ANE+V+ +G   R G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VTKKKLKQWFFTITKYAQELLDSLDDLPGWPEKVKIMQRNWIGRSEGVRLKFDVPSLGET  241
            V +K ++QW + IT YA+ LL+ L+++ +WPE +K MQRNWIG+S G  + F V   +  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  242  LETFTTRIDTIFGVTYIALSPEHPLVLKIIDSSSDGERIRSFA-EKIIKANATIRIAETE  300
            +  FTTR DT+FG TY  L+PEH+LV   I +S ++E +  +  +  +K++ +      E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALV-DAITTSDQAEAVADYKRQASLKSDLARTDLAKE  301

Query  301  KEGIFTGFYAVNPANGKAVPIWIANYVLMEYGTGAVMGVPAHDQRDFEFAQKYGIPIIPV  360
            K G+ TG YA+NP NGK +P+WIA+YVL  YGTGA+M+VPAHD+RD EFA+++ + IIPV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  361  VRPEGSELAELAHAFEEDGIACNSGQFDGLPTGEALKAMAEWAENEGFGKREVQYRLRDW  420
            +  EG+++ E   AF EDG+  NS+ +DGL  + A+  M EW E EG G+ +V YRLRDW
Sbjct  362  L--EGGNVEE--AAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDW  417

Query  421  LISRQRYWGTPIPVVYCDRCGVVPVPEKDLPVLLPT--NVQMPKDGHSPLPELEEWVNTT  478
            L+SRQRYWG PIP++  +     +VPE +LP++LP   +++ +  G+SPL+++ +W++ T
Sbjct  418  LFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT  477

Query  479  CPNCGGPAKRETDTLDTFVCSSWYFLRFCSPWCDDKPFDDE-VHYWTPVDQYIGGIEHAC  537
              + G  ++RET+T+     SSWY+LR+  P   +K  D+E +  W PVD Y+GG EHA 
Sbjct  478  RED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  538  LHLIYSRFFTKVLADMGLIRFREPFQNLLTQGMVI-------------------KDG---  575
            LHL+Y+RF  KVL D+G++  +EPFQ+L+ QGM++                   +DG   
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFF  596

Query  576  ------------AKMSKSKGNVVDPDDIIKRYGADTARLFILFASPPDKDLEWSDQGVEG  623
                        AKMSKS  NVV+PDD++ +YGADT R++ +F +P D  + WS++G+EG
Sbjct  597  HVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEG  656

Query  624  VYRFLSRLWRYMEENMEQLNKAALEHVAMDALSEPRKRDLKRRIHRTIELVTRDIEVERQ  683
              +FL R+ R                ++   ++E     L +  + T+  VT +++ + +
Sbjct  657  SRKFLDRVYRL---------------ITTKEITEENSGALDKVYNETVKAVTEQVD-QMK  700

Query  684  FNTAVARFMELFNDMYSYEPKDGADWALLREAAETLIVCLSPFVPHICEELWERLGHKEM  743
            FNTA+A++M +F +  + E K      L+ + A  ++  ++PF PH+ EELW+ L     
Sbjct  701  FNTAIAQLM-VFVNAANKEDK------LFSDYAKGFVQLIAPFAPHLGEELWQALTASGE  753

Query  744  VVR-QPWPNVDPTALVEDEITLVVQINGKVRERLTVPAGLSREEIERRVLDDPRVQRRLE  802
             +   PWP+ D + LVE+++ +VVQI+GKV+ +L V+ +LSREE++   L + +VQ  + 
Sbjct  754  SISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIA  813

Query  803  GQRLIKTIVVPDKLVNLVVK  822
            G+ +IK I VP+KLVN+V+K
Sbjct  814  GKDIIKVIAVPNKLVNIVIK  833

817) leuS in NC_011959


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  574 bits (2169),  Expect = 7e-165, Method: Compositional matrix adjust.
 Identities = 380/853 (45%), Positives = 546/853 (65%), Gaps = 63/853 (7%)

Query  13   YEPQVIEPKWQQIWEETGIYSNVQEDPTRPKWYHLVMFPYPSG-NLHIGHWFSYAPADAA  71
            Y+   IEPKWQ +W +   + +   D+++PK Y L MFPYPSG  LH+GH  +Y+++D  
Sbjct  4    YDHTAIEPKWQAFWADNHTF-KTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDIL  62

Query  72   ARYKRMRGYNVLFPFGFDAFGLPAENAAIKHGIHPRVWTMQNIAHMKKQLRSLGGMFDWS  131
            +R+KR +G NVL P G DAFGLPAE+ A+  G +P   T +NIA+ K+Q+ +LG  +DW 
Sbjct  63   SRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWD  122

Query  132  KEVITCLPEYYRWNQWFFLQFYKRGLAYRAKAPVWWCPTCQTVLANEQVI-DGRCERCST  190
            +EV T  P+YY+W QW+F ++Y +GLAY A  PV W     T +ANE+V+ DG  ER + 
Sbjct  123  REVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGY  182

Query  191  EVYRRDLEQWFLRITAYAEELLR-FDGIDWPERVITMQRNWIGRSEGARIVFRSEQGD-P  248
             V R+ + QW L+ITAYAE LL  ++ +DWPE +  MQRNWIG+S GA + F+  + D  
Sbjct  183  PVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  249  IEVFTTRPDTLWGATFLVLAPEHPLVQKLTTPERRAEVEAYIDQARRRSDIERTSTEREK  308
            + VFTTRPDTL GAT+ VLAPEH+LV+ +TT+++   V  Y  QA  +SD+ RT   +EK
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEK  302

Query  309  TGVFIGAYAINPANGQRIPIWIADYVLMQYGTGAIMAVPAHDQRDFEFARAFGLPIVVVI  368
            TGV  G+YAINP NG+ +P+WIADYVL  YGTGAIMAVPAHD+RD EFA+ F L I+ V+
Sbjct  303  TGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL  362

Query  369  QPRDRTLDPATMEEAYDGEGVMVNSGPFDGTPTEGGEAIRRVIAWLEERGVGRGEVTYRL  428
            +      +    E A+  +G+ +NS+ +DG   + + AI +++ WLE  GVG  +VTYRL
Sbjct  363  E------GGNVEEAAFTEDGLHINSDFLDG--LDKASAIAKMVEWLEAEGVGNENVTYRL  414

Query  429  RDWLISRQRYWGTPIPIVYCDHCGIVPVPEDQLPVLLPEDAEFMP--TGQSPLITHEAFV  486
            RDWL+SRQRYWG PIPI+  ++    +VPE +LP++LP   ++ P  TG+SPL      +
Sbjct  415  RDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWL  474

Query  487  NTTCPQCGAPARRETDTMDTFVDSSWYWYRYLSPHENERPFDPEKVAYWTPVDQYTGGIE  546
            + T  + G  +RRET+TM    +SSWY  RY+ PH+ E+  D E +  W PVD Y GG E
Sbjct  475  EVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAE  533

Query  547  HAILHLLYSRFWTKALADLGLVNHREPFLRLFNHGVILG---------------------  585
            HA+LHLLY+RFW K L DLG+V  +EPF +LFN+G+ILG                     
Sbjct  534  HAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDG  593

Query  586  ------------EDGEKMSKSRGNVVDPDDLVARLGADTVRLYLMFIGPWSQGGPWSSRG  633
                        +   KMSKS  NVV+PDD+V + GADT+R+Y MF+GP   + +WS  G
Sbjct  594  SFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEG  653

Query  634  VAGVQRFLQRVWALVTETLDVPVDTAEDEQARALRRLVHRTIKHVTDDFETFSFNTAIAR  693
            + G ++FL+RV  L+T           +E++ AL ++ + T+K VT++ +   FNTAIA+
Sbjct  654  LEGSRKFLDRVYRLIT------TKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQ  707

Query  694  MMELVNELSRLRETTVVRMPVWREALETLVLLLAPGAPHLAEELWQRL-GKPYSVHQQSW  752
            +M +VN  ++          +  +    +V L+AP APHL+EELWQ L +   S+   +W
Sbjct  708  LMVFVNAANK-------EDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPW  760

Query  753  PAYDPALAAEETVELVIQVNGRVRDRLLVPAAIDEDEAVARARELERVQAYLAGKRIERV  812
            P+YD +   E+ VE+V+Q++G+V+ +L+V+  +  +E    A   E+VQA +AGK I +V
Sbjct  761  PSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKV  820

Query  813  VYVPGRLVNFVVS  825
            + VP +LVN+V+ 
Sbjct  821  IAVPNKLVNIVIK  833

818) Dole_2438 in NC_009943


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  573 bits (2165),  Expect = 1e-164, Method: Compositional matrix adjust.
 Identities = 357/863 (42%), Positives = 558/863 (65%), Gaps = 39/863 (4%)

Query  8    YRPGEIEARWQETWNRTAIFRAAEDGKKEKYYLFEMFPYPSGR-IHMGHVRNYTIGDVVA  66
            Y    IE++WQ  W     F+++ D+ K K+Y ++MFPYPSG  +H+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  67   RYKMMKGFNVLHPMGWDAFGMPAENAAIANNTHPARWTRENIAYMRAQLKRMGLSYDWDR  126
            R+K  +G NVLHPMGWDAFG+PAE+ A+    +PA  T ENIA  + Q++ +G+SYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  127  EIATCDPDYYRWEQWLFVKMYEKGMAYRKDAFVNWCDTCATVLANEQV-EAGACWRCGHA  185
            E+ T DP+YY+W QW+F K+YEKG+AY  +  VNW +  +T +ANE+V   G+  R G +
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  186  VRQKKLAQWFFRITDYAEDLLVYCDQLPGWPERVTTMQKNWIGKSVGAEIRFPVKDSDIQ  245
            V +K + QW ++IT YAE LL   +++ +WPE +  MQ+NWIGKS GA++ F VKD+D +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  246  IPVFTTRQDTVFGATFLCLAPEHPLVTQLAAGTQQEAAVNAFVEKMTLTDRTSKAVESYE  305
            + VFTTR DT+FGAT+  LAPEH+LV  ++++ Q E AV  +  + +L    +++  + E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAE-AVADYKRQASLKSDLARTDLAKE  301

Query  306  KEGVFIGAFCVNPVTGRSMPVYTANFALMEYGTGAVMSVPAHDQRDFEFAKKYDLDIVVV  365
            K GV  G++ +NPV G+ MPV  A++ L  YGTGA+M+VPAHD+RD EFAK+++LDI+ V
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  366  VKPADADLAAEIMTEAFTGRGVMINSGPFDGIDSGAALDAIAEYLEEKGIGKKTVSFRLR  425
            +  ++ +        AFT  G+ INS+ +DG+D ++A+  + E LE  G+G+  V++RLR
Sbjct  362  LEGGNVE------EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  426  DWGISRQRYWGAPIPMVHCDACGIVPVPEADLPVVLPEDADL--LEGGRSPLPVLESFVS  483
            DW +SRQRYWG PIP++H +     +VPE++LP+VLP   D+     G SPL+ +   + 
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWL-  474

Query  484  AVCPKCGKKARRETDTMDTFVDSSWYYLRYCSPECDHAIFDPAAVRYWMPADQYIGGVEH  543
             V    G K+RRET+TM    +SSWYYLRY  P+  + + D   ++ W+P D Y+GG EH
Sbjct  475  EVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEH  534

Query  544  AILHLLYSRYFTRVLHDLDLVDFKEPFTRLLTQGMVCKETYACEAHGFLYPEEVGKTDAG  603
            A+LHLLY+R+  +VL DL++V  KEPF +L+ QGM+   +Y     +++  + V K D G
Sbjct  535  AVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRD-G  593

Query  604  DLVCVKCEGPVTVGRVEKMSKSKKNVIDPNFLLDKYGADVTRLFCLFASPPEKGLEWSDQ  663
             +  V     +  +   KMSKS KNV++P+ ++++YGAD  R++ +F +P + ++ WS++
Sbjct  594  SFFHVETGEELEQAPA-KMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEE  652

Query  664  GVEGSYRFLNRVWRFFVEWMDAIDGVAPYKGDVTALPDALQGLYRKTHQTIGRVTADIEE  723
            G+EGS +FL+RV R++             K      ++AL+ +Y   ++T+  VT ++++
Sbjct  653  GLEGSRKFLDRVYRLITT-----------KEITEENSGALDKVY---NETVKAVTEQVDQ  698

Query  724  RFHFNTAISAVMELVNEMYTISDRQDPTARQVMRHAAETVILLLSPIVPHLCEELWAGLG  783
               FNTAI+ +M +VN     ++++D    ++  + A   + L++P+ PHL EELW +L 
Sbjct  699  -MKFNTAIAQLMVFVNA----ANKED----KLFSDYAKGFVQLIAPFAPHLGEELWQALT  749

Query  784  HTESILRH-PWPAFSSeaaaeqevlvvvqvNGKLRDRFTAPADADVKTLEAKALACEQAQ  842
             +   +   PWP++      E++V +VVQ++GK++ ++  + D     L+  ALA E+ Q
Sbjct  750  ASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQ  809

Query  843  KFVAGKPVRKVIVVPGKLVNIVV  865
              +AGK + KVI VP KLVNIV+
Sbjct  810  AEIAGKDIIKVIAVPNKLVNIVI  832

819) leuS in NC_005070


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  573 bits (2164),  Expect = 2e-164, Method: Compositional matrix adjust.
 Identities = 373/858 (44%), Positives = 566/858 (66%), Gaps = 36/858 (4%)

Query  5    YSPADLEQRWQTTWRSE-GLDVTPEPEDGKGFYALSMFPYPSGT-LHMGHVRNYVITDVI  62
            Y  + +E +WQ+ W  +  +    ++   K FYAL MFPYPSG+ LH+GH   Y  TD++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPK-FYALDMFPYPSGAGLHVGHPEGYTATDIL  62

Query  63   ARVQRMRGHSVLHPMGWDAFGLPAENAAIERNVDPGDWTDRNIDQMRSQLDRLGLSIDWD  122
            +R +R +GH+VLHPMGWDAFGLPAE+ A++   DP++ T  NI + + Q++ LG+S DWD
Sbjct  63   SRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWD  122

Query  123  REQATCHSDYYRWTQWLFLELFDGGLAYRKNATVNWDPVDQTVLANEQVDADGRSWRSGA  182
            RE  T +++YY+WTQW+F  L++ GLAY  +  VNW     T +ANE+V +DG S R+G 
Sbjct  123  REVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGY  182

Query  183  LVEQRQLNQWFLRITQYAEALLNDLDQLSGWPERVRTMQANWIGRSEGAEIQFKVSSDSD  242
             V ++ + QW L+IT YAE LL+DL+++ +WPE ++ MQ NWIG+S GA++ FKV  D+D
Sbjct  183  PVVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKV-KDTD  240

Query  243  TTITVFTTRPDTLAGASCVVLAPDHPLVNSLTSPDQQDVVQAFQAEVARLSALERTSDDA  302
              +TVFTTRPDTL GA+  VLAP+H+LV+++T++DQ + V  ++ + +  S L RT    
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  303  PKRGVFTGATVLNPLNGRALPVWIADYVLVDYGTGAVMGVPAHDQRDRRFAQSYGLavqq  362
             K GV TG+  +NP+NG+ +PVWIADYVL  YGTGA+M+VPAHD+RD+ FA+ + L +  
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  363  vieaegaaaaiaageaWTDPGVLIHSGDFDGLNSIEAKERITRHGEQQGWAVAKVTYRLR  422
            V+E+     A       T+ G+ I+S+ +DGL+   A  ++    E +G +  +VTYRLR
Sbjct  361  VLEGGNVEEAAF-----TEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  423  DWLISRQRYWGCPIPIIHCPSCGAVPVPREDLPVVLP--RGIDLSGKGGSPLEQQQDWVN  480
            DWL+SRQRYWG PIPIIH     + +VP  +LP+VLP  ++I  SG G SPL +  DW++
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  481  VPCPSCGEPAKRETDTMDTFMCSSWYFLRFADPHNTEQPFSREAVNRWLPVQQYVGGIEH  540
            V     G  ++RET+TM     SSWY+LR+ DPHNTE+    E +++WLPV+ YVGG EH
Sbjct  476  VTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEH  534

Query  541  AILHLLYSRFFTKALKDRGLIDVAEPFDRLLTQGMVQGTTYRNPSTGKYVASADVSDPET  600
            A+LHLLY+RF  K L D G++   EPF++L+ QGM+ GT+YR+ S G  VA+  V   + 
Sbjct  535  AVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRD-SRGALVATDKVEKRDG  593

Query  601  P-TDPTSGEPLEVLFEKMSKSKYNGVDPAAVIDRYGADTARMFILFKAPPEKDLEWDDSD  659
            +  +  +GE LE    KMSKS  N V+P  V+++YGADT R++ +F +P +  + W + +
Sbjct  594  SFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEG  653

Query  660  VEGQFRFLQRIWRLVESADSRIDSLEPEERPEPLADTDAKVRRAIHIAIDAVSEDLQDEI  719
            +EG  +FL+R+ RL+ + +        EE + +L        +  + ++ AV+E++ D++
Sbjct  654  LEGSRKFLDRVYRLITTKEI------TEENSGALD-------KVYNETVKAVTEQV-DQM  699

Query  720  QLNTAISELMKLTNAITSVGVAELSTSVLKEALSTLLRLLAPFAPHLAEELWHQLGGTS-  778
            ++NTAI++LM +      V  A+    ++ +    +++L+APFAPHL+EELW+ L +++ 
Sbjct  700  KFNTAIAQLMVF------VNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGE  753

Query  779  SVHRAGWPELDPSALVQDSVDLVIQIKGKVRGTIQVPAAADKeqlealalaseiaaKWLE  838
            S+    WP  D S LV++ V++V+QIKGKV++ + V+    +E+L+ +ALA+E     + 
Sbjct  754  SISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIA  813

Query  839  GHPPRRVIVVPGKLVNLV  856
            G    +VI VP KLVN+V
Sbjct  814  GKDIIKVIAVPNKLVNIV  831

820) leuS in NC_009828


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  573 bits (2162),  Expect = 2e-164, Method: Compositional matrix adjust.
 Identities = 367/855 (43%), Positives = 545/855 (64%), Gaps = 63/855 (7%)

Query  1    MPRYEPQEIESKWQKFWEKEGLFKTPQHSDLPKYYMLVMFPYPSGT-LHVGHVKNYVIGD  59
            M  Y+   IE+KWQ FW  +  FKT  ++  PK+Y L MFPYPSG+ LHVGH   Y   D
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  60   AVARYKRMRAYNVLHPFGYDAFGLPAENAAIERKIHPKDWTLnniniiRRQIKKLGISYD  119
             ++R+KR ++ NVLHP G DAFGLPAE+ A++   +P + T +NI  ++RQI+ LG+SYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  120  WNREVITCLESYYKWTEWIFLKLYEAGLAYKKKAAVNWCPKCMTSLANEQV-KDGRCERC  178
            W+REV T   +YYKWT+WIF KLYE GLAY    +VNW     T++ANE+V  DG  ER 
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  179  DTPVTIKHLEQWFFKITDYAERLLKDLDKLTGWPEHVKTMQRNWIGESKGAKISFKVEES  238
            + PV  K + QW +KIT YAERLL DL+ + +WPE +K MQRNWIG S GA+++FKV ++
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDT  239

Query  239  EMNIEVFTTRPDTLWGVTFMVLAPESDLVNHITLPELKGELEKFLNYVGQQDRHKRGSAD  298
            + ++ VFTTRPDTL G T+ VLAPE  LV+ IT ++    +  +    + +    R    
Sbjct  240  DKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA  299

Query  299  VEKEGFFTGRYAINPVSGERIPIYVANYVLMEYGTGAVMGVPAHDQRDYEFAVKYNLPIK  358
             EK G  TG YAINPV+G  +P+ +A+YVL  YGTGA+M+VPAHD+RD EFA ++NL I 
Sbjct  300  KEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDII  359

Query  359  EVIKPSEDIPKNRAYDGPGIMVNSGPLNGTVVPEGIERVIQWLEERGIAKRSVQYKLRDW  418
             V+  ++    + A+   G+ +NS+ L+G   + +I ++++WLE  G+++ +V Y+LRDW
Sbjct  360  PVLEGGN--VEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDW  417

Query  419  LISRQRYWGAPIPIVYCEKCGMVPVPEKSLPVQLPYDVEFLP--TGQSPLMLNDEFRKTS  476
            L+SRQRYWG PIPI+  E     +VPE  LP+ LP   ++ P  TG+SPL    +    +
Sbjct  418  LFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT  477

Query  477  CPKCGGPALRDADTMDTFVDSSWYFLRYVNPDRDDVPFVKEDVDHWLPVDQYVGGVEHAV  536
                G  + R+++TM    +SSWY+LRY++P+  +     E + +WLPVD YVGG EHAV
Sbjct  478  RED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  537  LHLLYSRFITKVLYDLGYLSFDEPFENLFTQGMI----YKDG------------------  574
            LHLLY+RF  KVLYDLG ++  EPF++LF QGMI    Y+D+                  
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFF  596

Query  575  ------------AKMSKSKGNVVSPDEMIDRYGADTLRMYILFMGPPERDAEWNDAGIEG  622
                        AKMSKS  NVV+PD+++++YGADTLR+Y +FMGP +    W++ G+EG
Sbjct  597  HVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEG  656

Query  623  VYRFIRRAWSLMDQIISLPDNQNQVFAEEEKHLRRKLHISLRKVTQDMEGGFKFNTVVSS  682
              +F+ R   L+          +++  E+   L +  + +++ VT++++   KFNT ++ 
Sbjct  657  SRKFLDRVYRLI--------TTKEITEENSGALDKVYNETVKAVTEQVD-QMKFNTAIAQ  707

Query  683  LMELVNDAYDYIDNLPQHRWNIKLLKELAKNFVLMISPFAPHFAEELWQRMGYSSSVMK-  741
            LM +VN A            + KL+ + AK FV +I+PFAPH++EELWQ +  S+  +  
Sbjct  708  LMVFVNAANK----------EDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISY  757

Query  742  EKWPEYDPDALVVEEVEIAIQVNGKLRDKVKIPVDATEDQIKEIALKSEKVRKYISD-EP  800
              WP YD   LV ++VEI +Q++GK++ K+ ++ D + ++++E+AL +EKV+  I++ + 
Sbjct  758  VPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDI  817

Query  801  KKIIYVPKRLLNIIF  815
             K+I VP++L+NI++
Sbjct  818  IKVIAVPNKLVNIVI  832

821) leuS in NC_014328


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  572 bits (2160),  Expect = 3e-164, Method: Compositional matrix adjust.
 Identities = 369/843 (44%), Positives = 548/843 (66%), Gaps = 58/843 (6%)

Query  7    DKKWQAKWEETSLYKFDDNNLDKKLYVLEMFSYPSGSKLHAGHWFNYAPVDSWARLKKMQ  66
            + KWQA W +   +K + +    K+Y L+MF+YPSG+ LH GH   Y++ D  +R+K+ Q
Sbjct  10   EPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSRFKRAQ  69

Query  67   GYNVFQPMGFDSFGLPAENYAIKTGIHPSDSTEKNIATMEKQLKSMGAMFNWENEVITCR  126
            G NV++PMG D+FGLPAE+YA+ TG +P++ T  NIA   +Q++++G  ++W+ EV T  
Sbjct  70   GHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDREVNTTD  129

Query  127  PEYYKWNQWLFLQLYKHGLAYRKNAPVNWCPSCKTVLANEQV-QDGFCERCGTEATKKDL  185
            P+YYKW QW+F +LY  GLAY  + PVNW     T +ANE+V  DG  ER G    +K +
Sbjct  130  PNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPM  189

Query  186  TQWFFKITDYSEELLQCLDKLDWPEKTKAMQRHWIGKSTGTNVTFKVADSDIEFSVFTTR  245
             QW +KIT Y+E LL+ L+ +DWPE  K MQR+WIGKSTG+NVTFKV D+D +F+VFTTR
Sbjct  190  RQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTR  249

Query  246  VDTLFGVTYVVLSPENTLVDKLTkeeykdevekykeSAKKQSEIERQSITREKTGVFSGS  305
             DTLFG TY VL+PE++LVD +T  +  + V  YK  A  +S++ R  +++EKTGV +GS
Sbjct  250  PDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGS  309

Query  306  YAINPINGRKVPIWIGDYVLNTYGTGAVMAVPAHDERDFAFATKYKLPIERVIEGG--DS  363
            YAINP+NG+ +P+WI+DYVL +YGTGA+MAVPAHDERD  FA +++L I  V+EGG  + 
Sbjct  310  YAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEE  369

Query  364  LPYVEHGKMINSGEFNGLTTKEGKEAVTKKLESMGLGSGKVNYRLRDWLISRQRYWGTPI  423
             ++ E+G  INS+ ++GL    +   +   LE+ G+G+ +V YRLRDWL+SRQRYWG PI
Sbjct  370  AAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPI  429

Query  424  PIVYCEKCGIVPVPEDQLPVELPYNVEFSPDGK--SPLLKSEEFMNTTCPCCGGPAKREA  481
            PI+  E     +VPE +LP+ LP   ++ P G   SPL +  + ++ T    G  ++RE+
Sbjct  430  PIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRE-DGVKGRRET  488

Query  482  DTLDTFVCSSWYYLRYVDNKNSEKPFDKAKIDKMLPVDMYVGGPEHACMHLLYARFITKA  541
            +T+     SSWYYLRY+D  N+EK  D   + + LPVD+YVGG+EHA +HLLYARF  K 
Sbjct  489  NTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWHKV  548

Query  542  LRDMGFLDFDEPFLSLRHQGIILGP---------------------------------DG  568
            L D+G +   EPF  L +QG+ILG                                    
Sbjct  549  LYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEELEQAP  608

Query  569  QKMSKSKGNTISPDDCIQEYGSDVFRMYLMFGFDYSEGGAWNDDGIKSISKFVDRIERTI  628
             KMSKS  N ++PDD +++YG+D +R+Y MF      + AW+++G+ +  KF+DR+ R I
Sbjct  609  AKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLI  668

Query  629  SSVKEIIESGDTGKTSMDAAEKELNYTRNFSIKSVSEDANKFQFNTSIARIMEFTNALSK  688
            ++ KEI E    +   +        Y    ++K+V+E+ ++ +FNT+IA++M F NA   
Sbjct  669  TT-KEITEENSGALDKV--------YNE--TVKAVTEQVDQMKFNTAIAQLMVFVNA---  714

Query  689  YIQQKDKNISLLKDTVIDFVKIIAPFAPHFAEEQWESL-GKSYSIFNEKWPDFEPNALIR  747
                 +K+  L+ D   +FV++IAPFAPH++EE W++L + + SI    WP ++ + L+ 
Sbjct  715  ----ANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVE  770

Query  748  DEAEIAIQINGKIKAKINVSTNLKEDQIKELSLSNEHIKSLLdgkdikkvivvkgRLVNI  807
            ++ EI +QI+GK+KAK+ V+ +L  ++++E++L+NE +++ + GKDI KVI V  +LVNI
Sbjct  771  NDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNI  830

Query  808  VAK  810
            V K
Sbjct  831  VIK  833

822) leuS in NC_010337


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  572 bits (2161),  Expect = 3e-164, Method: Compositional matrix adjust.
 Identities = 382/881 (44%), Positives = 559/881 (64%), Gaps = 90/881 (10%)

Query  5    YDYQQIEKKWQKYWADTGMFRLQQEEGRPKYYCLEMFPYPSG-NLHMGHVRVYSIGDVVA  63
            YD   IE KWQ +WAD   F+   + ++PK+Y L+MFPYPSG  LH+GH   Y+  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RFKTMQGYNVLHPMGWDAFGLPAENAAIKHKVPPADWTWSNIANMRRQLQSMGISYDWER  123
            RFK  QG NVLHPMGWDAFGLPAE+ A+     PA+ T  NIAN +RQ++++G+SYDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVATCHPDYYKWTQWLFLQlykaglaykkkaNVNWCPDCATVLANEQVV-DGLCERCDAT  182
            EV T +P+YYKWTQW+F +LY  GLAY     VNW  + +T +ANE+V+ DG  ER +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VEKKALEQWFFRITDYAQRLLDDLNKLPGWPDKVKTMQENWIGRSEGVEADFALENPVGG  242
            V +K++ QW ++IT YA+RLL+DL+ + +WP+ +K MQ NWIG+S G +  F + +    
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDT---  239

Query  243  VDKLTVYTTRQDTIFGVTYMVLAPEHPAVEALVSGNPREAELRAFIKKVLSQSEIDRTAN  302
               +TV+TTR DT+FG TY VLAPEH+ V+A+ +++  EA +  + ++   +S++ RT  
Sbjct  240  DKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEA-VADYKRQASLKSDLARTDL  298

Query  303  DTEKEGIFTGHYCINPLTGEKVAVYLANYVLVDYGTGAVMGVPAHDQRDFEFATKYNIPM  362
              EK G+ TG Y INP+ G  ++V +A+YVL  YGTGA+M+VPAHD+RD EFA ++N+ +
Sbjct  299  AKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDI  358

Query  363  KVVIQPEGLPDLDVEEMDHAYEGEGRLVNSGEFDGLINTQALDVIADKLEREGKGVRKVN  422
              V++   +        + A+  +G  +NS+ +DGL ++ A+  + + LE EG G  +V 
Sbjct  359  IPVLEGGNVE-------EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVT  411

Query  423  YRLRDWLISRQRYWGAPIPVIYCEKCGEVAVPDEQLPVMLPTDVAFTPS--GESPLTSRP  480
            YRLRDWL+SRQRYWG PIP+I  E     AVP+ +LP++LP    + PS  GESPL++  
Sbjct  412  YRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVT  471

Query  481  DFYECTCPRCGGKGRRETDTMDTFVCSSWYFLRYCTPKDKDHAFLQEDVDYWMNVDQYIG  540
            D  E T    G KGRRET+TM     SSWY+LRY  P + +    +E +  W+ VD Y+G
Sbjct  472  DWLEVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVG  530

Query  541  GVEHAILHLMYARFFTKVLYDLKLVKVEEPFENLLTQGMVL-------------------  581
            G EHA+LHL+YARF  KVLYDL +V   EPF++L+ QGM+L                   
Sbjct  531  GAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEK  590

Query  582  ---------------MGGSKMSKSKGNTVSPEEIIAKYGADTARLFILFAAPPERDLEWS  626
                            + +KMSKS  N V+P++++ +YGADT R++ +F +P +  + WS
Sbjct  591  RDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWS  650

Query  627  DRGVEGAHRFLHRLWRLVYAYSDQIASVPGTMVGYGKGQPNGSKGDNLFSLNSDDRELVR  686
            + G+EG+++FL+R+ RL+ +                K   + + G            L +
Sbjct  651  EEGLEGSRKFLDRVYRLITT----------------KEITEENSG-----------ALDK  683

Query  687  VAHYTVKKVTEDIGQRFNFNTAVSAIMEMVNYFYQYKDKVPAEQQNIPLVKDALARLVLV  746
            V + TVK VTE+++Q  +FNTA++ +M  VN          A +++  L  D    +V +
Sbjct  684  VYNETVKAVTEQVDQ-MKFNTAIAQLMVFVN----------AANKEDKLFSDYAKGFVQL  732

Query  747  LAPFAPHICEELWQVI-GGGESVYKQPWPTYDEQALVRDEVEVVVQINGKVREKLRVANG  805
            +APFAPH+ EELWQ + ++GES+   PWP+YDE  LV ++VE+VVQI+GKV+ KL VA++
Sbjct  733  IAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKD  792

Query  806  LDGEAIKAKVLEMDKVQALIAGKSVVKLITVPNKLVNIVVK  846
            L  E ++   L  +KVQA IAGK ++K+I+VPNKLVNIV+K
Sbjct  793  LSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

823) leuS in NC_018870


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  572 bits (2160),  Expect = 3e-164, Method: Compositional matrix adjust.
 Identities = 370/863 (43%), Positives = 559/863 (65%), Gaps = 73/863 (8%)

Query  4    YNFRLIEKKWQRRWEETDAFRATEDAAGQKYYCLVMFPYPSG-NLHMGHVRNYAIGDVIA  62
            Y+   IE KWQ  W + ++F++  DA+  K+Y L MFPYPSG  LH+GH   Y+  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RFYRMNGYNVLHPMGWDAFGLPAENAAIKNRIPPAKWTWGNIENMRRQLRSLGLSYDWSR  122
            RF R +G NVLHPMGWDAFGLPAE+ A+     PA  T  NI N +RQ+ +LG+SYDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVTTCHPEYYRWTQWLFLQLYHRGLAYRKKQAVNWCPSCATVLANEQVV-GGRCERCDTE  181
            EV T +P+YY+WTQW+F +LY++GLAY    +VNW    +T +ANE+V+ +G  ER +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VTTRDLEQWFFRITDYADRLLDDLKKLPGWPEKVKLMQENWIGKSHGAELEF-LAENGSR  240
            V  + + QW ++IT YA+RLL+DL  + +WPE +K MQ NWIGKS GA++ F + + +  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  241  ITVFTTRPDTVFGVTYLVLAPEHPLVEELIRGKAEARQVMEFVEKVRKQSEIERASAEGE  300
            +TVFTTRPDT+FG TY VLAPEH+LV+  I    +A  V ++  +   +S++ R+    E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDA-ITTSDQAEAVADYKRQASLKSDLARTDLAKE  301

Query  301  KEGVFTGAYAVNPISGEKVPIWVANYVLLEYGTGAVMGVPAHDQRDLEFARKYNLPVRVV  360
            K GV TG+YA+NP++G  +P+W+A+YVL  YGTGA+M+VPAHD+RD EFA+++NL +  V
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  361  IQPLGKNLDAATLEQAYDGPGVMVNSGRFDGLDSEVGRLKITEFAEEKGCGREKVNYRLR  420
            ++  G N++    E A+   G+ +NS+ +DGLD   +  K+ E  E  G G E+V YRLR
Sbjct  362  LE--GGNVE----EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  421  DWLISRQRYWGAPIPIIYCDRCGIvpvpeedlpvllpedvAFEP--TGESPLLKAEDFLN  478
            DWL+SRQRYWG PIPII  +     +VPE +LP++LP    + P  TGESPL +  D L+
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  479  TTCPRCGASARRETDTMDTFVCSSWYFLRYCSPQDREQAFDSSKVRYWMPVDQYIGGVEH  538
             T    G  +RRET+TM     SSWY+LRY  P++ E+  D   ++ W+PVD Y+GG EH
Sbjct  476  VTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEH  534

Query  539  AILHLMYSRFITKVLYDQGLVPCDEPFTNLLTQGMVL-------------------KDG-  578
            A+LHL+Y+RF  KVLYD G+VP  EPF +L+ QGM+L                   +DG 
Sbjct  535  AVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGS  594

Query  579  --------------AKMSKSKGNVVSPEEIIENYGADTARLFILFAAPPERDLDWSDQGV  624
                          AKMSKS  NVV+P++++E+YGADT R++ +F +P +  + WS++G+
Sbjct  595  FFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGL  654

Query  625  DGAYRFINRVWRLVQSLAPVIRDTGNTPDAGALGSQERELRRAIHRTIQRVTEDIKTRFN  684
            +G+ +F++RV RL+ +      ++G              L +  + T++ VTE++  + +
Sbjct  655  EGSRKFLDRVYRLITTKEITEENSGA-------------LDKVYNETVKAVTEQVD-QMK  700

Query  685  FNTAVSAIMELVNALYHYTEGTAEQEWHRDVLKEGISVLITLLAPFTPHLAEELWEAIGG  744
            FNTA++ +M +VNA       +  ++    ++ +    ++ L+APF+PHL+EELW+A+ +
Sbjct  701  FNTAIAQLMVFVNA-------ANKED---KLFSDYAKGFVQLIAPFAPHLGEELWQALTA  750

Query  745  KG-SVHEQKWPEADPEALKQEEINIAVQVNGRVRDHLDVPVGLSNRELEELVLAQPRINQ  803
             G S+    WP  D   L +++++I VQ++G+V+  L V+ +LS  EL+E+ LA+ +++ 
Sbjct  751  SGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQA  810

Query  804  LLQGKNLVKVVCVPGKLVNLVVK  826
             + GK+++KV+ VP KLVN+V+K
Sbjct  811  EIAGKDIIKVIAVPNKLVNIVIK  833

824) leuS in NC_007775


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  571 bits (2157),  Expect = 6e-164, Method: Compositional matrix adjust.
 Identities = 396/875 (46%), Positives = 582/875 (67%), Gaps = 52/875 (5%)

Query  5    YNPPAIESKWQAHWRELGLDRTPELTAESRKFYALSMFPYPSGS-LHMGHVRNYTITDVI  63
            Y+  AIE+KWQA W +    +T    A   KFYAL MFPYPSG+ LH+GH   YT TD++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGT-DASKPKFYALDMFPYPSGAGLHVGHPEGYTATDIL  62

Query  64   ARHKRMQGYAVLHPMGWDAFGLPAENAAIDRGIPPAKWTYQNIAQMRDQLQRLGLSYDWE  123
            +R KR QG  VLHPMGWDAFGLPAE+ A+D G  PA  T +NIA+ + Q++ LG+SYDW+
Sbjct  63   SRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWD  122

Query  124  REITTCAPDYYKWTQWLFLQFFKAGLAYQKEAPVNWDPVDQTVLANEQVDAEGRSWRSGA  183
            RE+ T  P+YYKWTQW+F +++  GLAY+ E PVNW     T +ANE+V ++G S R+G 
Sbjct  123  REVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGY  182

Query  184  LVEKRLLKQWFLKITAYADQLLADLEKLSGWPERVLTMQENWIGQSVGARVVFKT-ETGE  242
             V ++ ++QW LKITAYA++LL DLE + +WPE +  MQ NWIG+S GA V FK  +T+ 
Sbjct  183  PVVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDK  241

Query  243  ELPVFTTRPDTLWGATFMVLAPEHPLVEKLTTPEQevavkayraeaaarseiersaedre  302
            ++ VFTTRPDTL GAT+ VLAPEH+LV+ +TT++Q  AV  Y+ +A+ +S++ R+   +E
Sbjct  242  DFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKE  301

Query  303  KTGVWTGSYAINPVNQERIPIWIADYVLMGYGTGAIMAVPAHDQRDFEFARQFGLPIKLV  362
            KTGVWTGSYAINPVN   +P+WIADYVL +YGTGAIMAVPAHD+RD EFA+QF L I  V
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  363  VQPPQGGVTSAEDLQAAWTGEGVLINSGPLNGIPVGKGPGQSVERAIAWLEEQGLGERQV  422
            ++  +         +AA T +G+ INS+ L+G+    + + ++ + + WLE +G+G+ +V
Sbjct  362  LEGGNVE-------EAAFTEDGLHINSDFLDGL----DKASAIAKMVEWLEAEGVGNENV  410

Query  423  NYRLRDWLISRQRYWgcpipiih--cphcgivpvpeedlpvllpedvelTGRGGSPLAQL  480
             YRLRDWL+SRQRYWG PIPIIH        VP +E  L + +  D+  +G G SPLA++
Sbjct  411  TYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANV  470

Query  481  EDWVKVKCPACGADARRETDTMDTFICSSWYFLRFSDPRNDREIFRKDLVNAWLPVDQYV  540
             DW+ V     G  +RRET+TM     SSWY+LR+ DP+N   +   +L++ WLPVD YV
Sbjct  471  TDWLEVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYV  529

Query  541  GGIEHAILHLLYSRFFTKVLRDLGLLNFDEPFSRLLTQGMVQARTYYNPNKSGKDRWIPT  600
            GG EHA+LHLLY+RF  KVL DLG++   EPF +L+ QGM+ + +Y    + +++  ++T
Sbjct  530  GGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY----RDSRGALVAT  585

Query  601  ALVKDPNDP-RDPETGEPLQVIYATMSKSKGNGVDPEEVLANYGADTARMFILFKAPPEK  659
              V   +++  + ETGE L+   A MSKS  N V+P++V+ +YGADT R++ +F +P + 
Sbjct  586  DKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  660  DLEWDDADVEGQFRFLNRVWRQVYEFVVRGSGTESLQGKAAELLQAKVEAGSLTKAERDL  719
             + W + ++EG  +FL+R    VY ++     TE   G                     L
Sbjct  646  SIAWSEEGLEGSRKFLDR----VYRLITTKEITEENSG--------------------AL  681

Query  720  RRAVHTAIKEVSEDLEEYQFNTAIAGLMKLSNALAEAEIPDSPVYAEGIRTLVLLLAPFA  779
             +  + ++K V+E++++ +FNTAIA LM     + +A   +  ++++  + +V L+APFA
Sbjct  682  DKVYNETVKAVTEQVDQMKFNTAIAQLM----VFVNAANKEDKLFSDYAKGFVQLIAPFA  737

Query  780  PHMAEELWQALGGT-DSVHRQAWPTYDPAALVADTVTIVVQVNGKLRGSFEAPADVTPQE  838
            PH++EELWQAL ++ +S+   +WP+YD + LV + V IVVQ++GK+++ +  + D++ +E
Sbjct  738  PHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREE  797

Query  839  QERLALQSEAAQRYLQGMTPKRVIVVPKKLVNLVV  873
             + +AL +E  Q  + G    +VI VP+KLVN+V+
Sbjct  798  LQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

825) leuS in NC_011729


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  571 bits (2155),  Expect = 8e-164, Method: Compositional matrix adjust.
 Identities = 372/854 (44%), Positives = 577/854 (68%), Gaps = 31/854 (3%)

Query  5    YNAEAIEKKWQQTWVEMGLDQTPEDNTKPKYYALSMFPYPSG-NLHMGHVRNYVITDVIA  63
            Y+  AIE KWQ  W +    +T  D +KPK+YAL MFPYPSG  LH+GH   Y  TD+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RLKRMQGHRVLHPMGWDAFGLPAENAAIERGIHPAKWTYQNIAQMRQQLQQLGLSIDWSR  123
            R+KR QGH VLHPMGWDAFGLPAE+ A++ G +PA  T +NIA+ ++Q++ LG+S DW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVTTCSPDYYqwtqwlflqffqAGLAYQKEAAVNWDPVDQTVLANEQVDSEGKSWRSGAK  183
            EV T  P+YY+WTQW+F ++++ GLAY+ E +VNW     T +ANE+V ++G S R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  184  VERKMLRQWFLKITDYAEQLLNDLDKLPGWPEKVKLMQANWIGKSIGAYLEFPIVGMDEK  243
            V RK +RQW LKIT YAE+LL+DL+ + +WPE +K MQ NWIGKS GA + F + + D  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  244  IAVFTTRPDTVYGVTYVVLAPEHPLTPKVTTAKNKKAVEKFIKEVTSESEQERTAEDKPK  303
            ++VFTTRPDT++G TY VLAPEH+L   +TT+ +  AV  + ++ +  S+  RT   K K
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEK  302

Query  304  KGILTGGKAINPFNGQEVPILIANYVLYEYGTGAVMGVPAHDIRDFKFAQENKLPIRVVI  363
             G+ TG+ AINP NG+E+P+ IA+YVL  YGTGA+M+VPAHD RD  FA++ +L I  V+
Sbjct  303  TGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL  362

Query  364  VPEDQQDQDVTLTQAYTEPGIMVNSGSFDGMDSITGKTAIIDYAEKQGFGKARVQYRLRD  423
               + ++       A+TE G+ +NS+ +DG+D  ++ + +++  E +G G+  V YRLRD
Sbjct  363  EGGNVEE------AAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  424  WLISRQRYWGCPIPVIHCPSCGTVPVPDEDLPVKLP--EDVEFSGRGASPLAKLDSWINV  481
            WL+SRQRYWG PIP+IH     + +VP+ +LP+ LP   D+  SG G SPLA++  W++V
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  482  PCPSCGEPAKRETDTMDTFIDSSWYFLRYTDANDQQTAFSLDKVNDWMSVDQYVGGVEHA  541
                 G  ++RET+TM    +SSWY+LRY D+++ +     + +++W++VD YVGG EHA
Sbjct  477  TRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  542  ILHLLYSRFFTKVVRDRGLVDVDEPFQRLLTQGMVQGMTYKNPKTGKYIPSSQVNPEDPK  601
            +LHLLY+RF  KV+ D G+V   EPFQ+L+ QGM+ G +Y++++ G  +++ +V+  D  
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSR-GALVATDKVEKRDGS  594

Query  602  --DPETGEPLSVFYEKMSKSKYNGVDPKQVLAKYGADTARMFILFKAPPEKDLEWDDADV  659
              + ETGE L     KMSKS  N V+P +V+ +YGADT R++ +F +P +  + W + ++
Sbjct  595  FFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGL  654

Query  660  EGQFRFLNKVWRIVGEYQSNHkssskkkgsLTKVEKDLRRAIHIAIKEITEDLDGEYQFN  719
            EG  +FL++V R++    +    +  + G+L KV ++       ++K +TE++D + +FN
Sbjct  655  EGSRKFLDRVYRLI----TTKEITEENSGALDKVYNE-------TVKAVTEQVD-QMKFN  702

Query  720  TAVSELMKLSNALVDAKCYESPVYTEGVQTLLILLAPFAPHIAEELWHTL-GHSESVHLQ  778
            TA+++LM     +V+A   E  ++++  + ++ L+APFAPH++EELW++L + +ES+   
Sbjct  703  TAIAQLM----VFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYV  758

Query  779  GWPQLDPSALEVDEITLVIQIMGKTRGTIQVPSSATKEELEKFAFESEVAQRHLKDQEVK  838
             WP  D S L  +++ +V+QI GK ++ + V+   ++EEL+  A+ +E  Q ++ ++++ 
Sbjct  759  PWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDII  818

Query  839  KVIVVPGKLVNFVV  852
            KVI VP KLVN+V+
Sbjct  819  KVIAVPNKLVNIVI  832

826) Tlie_0702 in NC_016148


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  571 bits (2155),  Expect = 8e-164, Method: Compositional matrix adjust.
 Identities = 364/847 (43%), Positives = 540/847 (64%), Gaps = 73/847 (8%)

Query  3    YDFNTIEKKWQRYWEENGTFNVDVSEEKEKFYCLEMFPYPSGA-LHMGHLRNYSIGDMLA  61
            YD  +IE KWQ +W +N TF+ +    K KFY L+MFPYPSGA LH+GH   Y+  D+L+
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  62   RFLRMKGYNVLHPMGFDAFGLPAENAAIKYGTHPNKWTWDNIEHMTKQLKSMGCSYDWRR  121
            RF R +G NVLHPMG DAFGLPAE+ A+  G +P   T +NI +  +Q++++G SYDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  122  RVETCNPDYYKWTQWLFLQFYKKGLAYKKKAPVNWCESCSTVLANEQVINDGHCWRCGTP  181
             V+T +P+YYKWTQW+F ++Y KGLAY    PVNW E  +T +ANE+V+ DG   R G P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VVKKNLEQWFLRITDYAQELLDSLDELKGWPERVKIMQRNWIGRSEGVRLSFKVSGKDIE  241
            VV+K + QW L+IT YA+ LL+ L+E+ +WPE +K MQRNWIG+S G  ++FKV + D +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  242  IETFTTRIDTIFGVTFVALAVEHPLVEEIIKASPNGKEVEKFVKEHKAAPAETRGE-NAE  300
            +  FTTR DT+FG T+  LA EH+LV+  I +S ++  V  + ++    +  +R +   E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDA-ITTSDQAEAVADYKRQASLKSDLARTDLAKE  301

Query  301  KLGVDTGLRAINPVNGEEVPIWIANYILMEYGTGAIMGVPAHDQRDFEFARSYGIPIKVV  360
            K GV TG  AINPVNG E+P+WIA+Y+L  YGTGAIM+VPAHD+RD EFA+ + + I  V
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  361  INPKSGEKLDGKTMERAFEEDGIQVNSGPFDGMPTEEAKVKMAEWFEENGWGKREVNYRL  420
            ++       +G+  E AF EDG+++NS+ +DG+    A  KM EW+E +G G+ +V YRL
Sbjct  362  LE-------GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRL  414

Query  421  RDWLISRQRYWGAPIPVVYCESCGIVPVPEDQLPVELPLDVKMK---VGRNPLEDHHEWV  477
            RDWL+SRQRYWG PIP++  E     +VPE +LP+ LP+   ++    G +PL +  +W+
Sbjct  415  RDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWL  474

Query  478  NTKCPCCGRPAKRETDTMDTFICSSWYFLRFASPWTQEGPFRKEDVNYWMPVDQYIGGIE  537
            +       + ++RET+TM     SSWY+LR+  P   E     E ++ W+PVD Y+GG E
Sbjct  475  EVTREDGVK-GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAE  533

Query  538  HACLHLIYARFFTKFLADLGLVNVREPFANLLTQGMVI-------------------KDG  578
            HA LHL+YARF  K L DLG+V  +EPF +L+ QGM++                   +DG
Sbjct  534  HAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDG  593

Query  579  ---------------AKMSKSKGNVVDPDEIIRKYGADTARLFILFAAPPEKDLDWSDRG  623
                           AKMSKS  NVV+PD+++ +YGADT R++ +F +P +  + WS+ G
Sbjct  594  SFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEG  653

Query  624  VEGSHRFLNRVWRLVEENLEELKKASIRRLRMDEIKEKAARDLKRKIHKTIEDVTRDIEV  683
            +EGS++FL+RV RL+  +               EI E  +  L +  + T+  VT +++ 
Sbjct  654  LEGSRKFLDRVYRLITTK---------------EITEENSGALDKVYNETVKAVTEQVD-  697

Query  684  EKQFNTAVARLMELSNALGAFTPKDQDDWVIFREGVEVLLLCLSPVAPHISEELW-SLLG  742
            + +FNTA+A+LM + NA    + K++    +F +    ++  ++P APH++EELW +L +
Sbjct  698  QMKFNTAIAQLMVFVNA----ANKEDK---LFSDYAKGFVQLIAPFAPHLGEELWQALTA  750

Query  743  NDKLVCETSWPEVDPSALVEEEVNVVLQINGKVRAQLVVPANLDRESLKKRVLEDPQVVK  802
            ++  +   +WP  D S LVE++V++V+QI+GKV+A+LVV+ +L RE L+   L + +V  
Sbjct  751  SGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQA  810

Query  803  RLEGKEI  809
             + GK+I
Sbjct  811  EIAGKDI  817

827) Taci_0698 in NC_013522


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  571 bits (2155),  Expect = 9e-164, Method: Compositional matrix adjust.
 Identities = 354/864 (41%), Positives = 551/864 (64%), Gaps = 72/864 (8%)

Query  3    YDFGTIEPKWQKVWEESGAFHVERGGDKPKFYCLEMFPYPSGA-LHMGHLRNYSIGDLMA  61
            YD  +IEPKWQ  W ++ +F    ++ KPKFY L+MFPYPSGA LH+GH   Y+  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  62   RFLRMNGYNVLYPMGFDAFGLPAENAALKFGVQPAEWTWKNIEHMTGQLKKMGCSYDWRR  121
            RF R +G NVL PMG DAFGLPAE+ A+  G +PAE T  NI +   Q++ +G SYDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  122  RVETCNPDYYRWTQWLFLQFFKKGLAYRKEAPVNWCESCKTVLANEQVVDGGHCWRCGTA  181
             V+T +P+YY+WTQW+F +++ KGLAY  E PVNW E   T +ANE+V+ +G   R G +
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VTKRNLEQWFLRITDYAQELLDCLDSLEGWPERVRMMQRNWIGRSEGVRLSFAIDGTDLT  241
            V ++ + QW L+IT YA+ LL+ L+ ++ WPE ++ MQRNWIG+S G  ++F + +TD  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  242  MEAFTTRIDTIFGVTFVALAAENPLVRQLAAVSPKGDEMLAFAEKVMRQNEIERCAAGGE  301
               FTTR DT+FG T+  LA+E++LV  +++ S +++ +  +  +   ++++ R   + E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITT-SDQAEAVADYKRQASLKSDLARTDLAKE  301

Query  302  KEGFDTGFFAVSPVDGRKIPIWIANYILMDYGTGAIMGVPAHDQRDFEFARKYQLDVVPV  361
            K G  TG +A++PV+G+ +P+WIA+Y+L  YGTGAIM+VPAHD+RD EFA++++LD++PV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  362  IRPVDGPIPDGSSMDRAFEDEGIQCNSGQFDGLPTREAISKMALWFEENRWGKREVNYRL  421
                   + +G+  + AF ++G++ NS+ +DGL    AI+KM  W+E +  G+ +V YRL
Sbjct  362  -------LEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRL  414

Query  422  RDWLISRQRYWGAPIPVVYCDCCGIVPVPEDELPVKLPM--DVTVLEGGGSPLPGASHWV  479
            RDWL+SRQRYWG PIP++  +     +VPE ELP+ LP+  D+     G SPL+  ++W+
Sbjct  415  RDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWL  474

Query  480  NTSCPKCGGPARRETDTMDTFICSSWYFLRYTSPSSKDAPFDFDDVSYWMPVDQYIGGIE  539
            + +    G  +RRET+TM     SSWY+LRY  P + +   D + +  W+PVD Y+GG E
Sbjct  475  EVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAE  533

Query  540  HACLHLIYARFFTKVCSDLGLLPKDLREPFTNLLTQGMVI-------------------K  580
            HA LHL+YARF  KV  DLG++P   +EPF +L+ QGM++                   +
Sbjct  534  HAVLHLLYARFWHKVLYDLGVVPT--KEPFQKLFNQGMILGTSYRDSRGALVATDKVEKR  591

Query  581  DGS---------------KMSKSKGNVVDPDEIIRRYGADTARLFILFAAPPEKDLDWSD  625
            DGS               KMSKS  NVV+PD+++ +YGADT R++ +F +P +  + WS+
Sbjct  592  DGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSE  651

Query  626  KGVEGAHRFLSRVFRLVEENLEGLMSAPSPMDVDSIGDKALRDVKRQIHRTIDKVTRDIS  685
             G+EG+++FL RV+RL+  +    ++  ++  +D + + +++ V  Q++           
Sbjct  652  EGLEGSRKFLDRVYRLITTK---EITEENSGALDKVYNETVKAVTEQVD-----------  697

Query  686  KERQFNTAVASLMELCNSLQSLKPSSPEGWSVLREGVESLVLCLAPFTPHVCEELWSMLG  745
             + +FNTA+A LM + N+ +           ++ +   ++V  +APF+PH+ EELW  L 
Sbjct  698  -QMKFNTAIAQLMVFVNAANKED-------KLFSDYAKGFVQLIAPFAPHLGEELWQALT  749

Query  746  KNG-LVSLCGWPKADPKALEMEDVTVVFQENGKVREQLKVPAGLSKDQLAERVLSDPAVA  804
             +G  +S   WP  D   L  +DV +V Q +GKV+ +L V+ +LS+++L E  L++  V 
Sbjct  750  ASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQ  809

Query  805  KRLEGKEILKVIAVPDKLVNVVVK  828
              + GK+I+KVIAVP+KLVN+V+K
Sbjct  810  AEIAGKDIIKVIAVPNKLVNIVIK  833

828) Hprae_1340 in NC_017455


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  570 bits (2152),  Expect = 1e-163, Method: Compositional matrix adjust.
 Identities = 377/867 (44%), Positives = 567/867 (66%), Gaps = 75/867 (8%)

Query  4    YYPFQAVENKWLKNWEDSNLHKTGADPAKENYYVLEMFPYPSG-NLHMGHVRVYSIGDVI  62
            +Y   A+E KW   W D++  KTG+D++K ++Y L+MFPYPSG  LH+GH   Y+  D++
Sbjct  3    FYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDIL  62

Query  63   ARYKRMKGYNVLHPMGWDAFGLPAENAAIKHGNIHPKEWTWDNIAHMKEQMKAMGLSYDW  122
            +R+KR +G NVLHPMGWDAFGLPAE+ A+  GN +P E T +NIA+ K Q++A+G+SYDW
Sbjct  63   SRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGN-DPAEFTAENIANFKRQINALGFSYDW  121

Query  123  DHEVTTAAEDYYKWTQWFFTQMFNDDLAYKKESTVNWCPSCETVLANEQVVNDA-CERCG  181
            D+EV T+  +YYKWTQW+FT++++ +LAY  E  VNW     T +ANE+V+ D+  ER G
Sbjct  122  DREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGG  181

Query  182  TEVDLRDLEQWFLKITDYADRLLADHKELDGWPEKVKTMQKNWIGRSEGCRVNFALPKLE  241
              V  + + QW LKIT YA+RLL D  E+D WPE +K MQ+NWIG+S G  V F +   +
Sbjct  182  YPVVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  242  KDLEVFTTRPDTLFGATYMVLAPEHPYVAELTAGTKKEEEVQEFIQKVKKQKEQERTSAE  301
            KD+ VFTTRPDTLFGATY VLAPEH+ V  +T+ + + E V ++ ++   + +  RT   
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITT-SDQAEAVADYKRQASLKSDLARTDLA  299

Query  302  TEKLGVFTGAYAENPVNGKKIPIYIANYVLMGYGTGAIMAVPAHDQRDFDFAQKYDIEIT  361
             EK GV TG+YA NPVNGK +P+ IA+YVL +YGTGAIMAVPAHD+RD +FA++++++I 
Sbjct  300  KEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDII  359

Query  362  AVIQPENQKEELIGSKMKTAYTGDGYLINSEKYNGLQVEEAFTQMTADFSEAGFAKLETN  421
            +V++  N  E        +A+T DG  INS+  +GL+   A+++M   +   G ++ +  
Sbjct  360  PVLEGGNVEE--------AAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVT  411

Query  422  YRLRDWLISRQRYWGAPIPIIYCDDCGAVAVPEEDLPVKLPHDVEFSP--TGESPLKQVD  479
            YRLRDWL+SRQRYWG PIPII  +D  + AVPE +LP+ LP   ++ P  TGESPL +V 
Sbjct  412  YRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVT  471

Query  480  SFVNTSCPKCGKAAKRETDTMDTFVDSSWYFMRYADPKNKEVPFTKEKLDQWFPVDQYIG  539
              ++ +     K ++RET+TM    +SSWY++RY DP N E     E L QW+PVD Y+G
Sbjct  472  DWLEVTREDGVK-GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVG  530

Query  540  GIEHAILHLLYARFFTKVVYDMDLTEHVEPFTNWLAQGMVL-------------------  580
            G EHA+LHLLYARF  KV+YD+++    EPF + + QGM+L                   
Sbjct  531  GAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEK  590

Query  581  KDG---------------AKMSKSKGNVVDPKDILDEYGADTARLFILFAAPPEKDLEWS  625
            +DG               AKMSKS  NVV+P D++++YGADT R++ +F +P +  + WS
Sbjct  591  RDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWS  650

Query  626  DKGVEGADRFLNRVWRFVTENLELIKDTNSKLESSKLDPDAKALYRTMHASIKKVSEDIG  685
            + G+EG+ +FL+RV R++T + E+  + ++ L+          +Y   + ++K V+E+++
Sbjct  651  EEGLEGSRKFLDRVYRLITTK-EITEENSGALDK---------VY---NETVKAVTEQVD  697

Query  686  SRLNFNTAISSIMELTNEVYSYLNDRSSEETNAPLIKAVAENLVLLLAPFAPFITEELWE  745
             +++FNTAI+ +M        ++N  + E+    L+   A  +V L+APFAP + EELW+
Sbjct  698  -QMKFNTAIAQLM-------VFVNAANKEDK---LFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  746  -LLGHSKNVHKSDWPVYQEEALKKDELTIVIQVNGKVRDKIKIAADASeeevkaqvmeee  804
             L + + ++    WP Y+E  L  +++ IV+Q++GKV+ K+ +A D S EE++   + +E
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  805  kIKDYLADGNLVKTIYIPQKLVNLVIK  831
            K++  +A+ +++K I +P+KLVN+VIK
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVIK  833

829) leuS in NC_010003


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  570 bits (2151),  Expect = 2e-163, Method: Compositional matrix adjust.
 Identities = 373/863 (44%), Positives = 560/863 (65%), Gaps = 72/863 (8%)

Query  5    YNPQEIERKWQRNWQEKDAFKVSNEEYHKKYYDLVMFPYPSGT-LHVGHVKNYVIGDVIA  63
            Y+   IE KWQ  W ++++FK + +    K+Y L MFPYPSG+ LHVGH   Y   D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYKRMRGYNVMHPFGFDAFGLPAENAAIEKGNIHPEDWTMqniniirnqiKKLGISYNWE  123
            R+KR +G NV+HP G DAFGLPAE+ A++ GN +P + T +NI  ++ QI+ LG+SY+W+
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGN-DPAEFTAENIANFKRQINALGFSYDWD  122

Query  124  REVITCKEDYYKWTQWIFLQLYKNGLAYKKKAPVNWCPNCKTVLANEQVV-NGKCERCGT  182
            REV T   +YYKWTQWIF +LY +GLAY    PVNW  +  T +ANE+V+ +G  ER G 
Sbjct  123  REVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGY  182

Query  183  VVEIKQLEQWYFKITDYAEKLLYDLEKLSGWPENVKIMQKNWIGKSVGAEVEFNLDNGKG  242
             V  K + QW +KIT YAE+LL DLE + +WPE++K MQ+NWIGKS GA+V F++ +   
Sbjct  183  PVVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDK  241

Query  243  SLRVFTTRPDTLWGVTFMALAPESPLVEELTTPENSEKVNQFLQRVSLQDRFKRTAEGAE  302
             + VFTTRPDTL G T+  LAPE +LV+ +TT++++E V ++ ++ SL+  + RT  + E
Sbjct  242  DFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKE  301

Query  303  KEGVFTGSYAINPVNGEKIPIYVANYILYEYGTGAIMAVPAHDQRDFEFAKKYDLPIRIV  362
            K GV TGSYAINPVNG  +P+ +A+Y+L  YGTGAIMAVPAHD+RD EFAK+++L I  V
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  363  IMPEGDELTEENLEKAYIGEGVLVNSGEFTGLDNQTAIREVSQWLEDKKIGKVVTQYKLR  422
            +  EG+++ E     A+  +G+ +NS+ + GLD+ +AI  + +WLE   +G+    Y+LR
Sbjct  362  L--EGGNVEEA----AFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  423  DWLISRQRYWGAPIPVVYCEKCGVVPVPEKDLPVKLP--RDVAFEPTGKSPLIDHPDFKE  480
            DWL+SRQRYWG PIP++  E     +VPE +LP+ LP  +D+    TG SPL +  D  E
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  481  TTCPKCGGKAKREVDTMDTFVDSSWYYLRYVNPKLEDKPFNKEDVDNWLPVDQYIGGVEH  540
             T    G K++RE +TM    +SSWYYLRY++P   +K  + E + +WLPVD Y+GG EH
Sbjct  476  VTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEH  534

Query  541  AILHLLYSRFITKVLKDLGYVSFDEPFKNLFTQGMI----YRNG----------------  580
            A+LHLLY+RF  KVL DLG V+  EPF++LF QGMI    YR++                
Sbjct  535  AVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGS  594

Query  581  --------------AKMSKSKGNVVSPEEMIEKYGTDALRTYILFMAPPERDAEWNDSGI  626
                          AKMSKS  NVV+P++++E+YG+D+LR Y +FM+P +    W++ G+
Sbjct  595  FFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGL  654

Query  627  EGTYRFLNKVWNTYMKIQDKIIHLENKPNYPLKNKSEKDLRRKLHQTIEKITSDIEGNFQ  686
            EG+ +FL++V   Y  I  K I           + +   L +  ++T+  +T +++ + +
Sbjct  655  EGSRKFLDRV---YRLITTKEI----------TEENSGALDKVYNETVKAVTEQVD-QMK  700

Query  687  FNTAVsslmellnelnsylnnTDDKDWNLNLLKEFSEDFVLMLSPIAPHISEELWKNF-G  745
            FNTA+         +     N +DK     L+ +++ +FV +++P+APH++EELW+ + +
Sbjct  701  FNTAI-----AQLMVFVNAANKEDK-----LFSDYAKGFVQLIAPFAPHLGEELWQALTA  750

Query  746  KDEFIFKASWPEIDKNALKAEEITLAVQINGKLRAQITVDVSLNEDEVKSYALEDDKVQK  805
             +E I   +WP  D + L  +++ + VQI+GK++A++ V   L+ +E++  AL ++KVQ 
Sbjct  751  SGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQA  810

Query  806  YISGKKIQKIIYVPKKIINIVVK  828
             I+GK I K+I VP+K++NIV+K
Sbjct  811  EIAGKDIIKVIAVPNKLVNIVIK  833

830) leuS in NC_009718


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  570 bits (2154),  Expect = 9e-164, Method: Compositional matrix adjust.
 Identities = 368/857 (43%), Positives = 536/857 (63%), Gaps = 68/857 (7%)

Query  4    YKPQEIESKWQGVWSEKKVFETPQYSDKKKYYALVMFPYPSGT-LHVGHVKNYVIGDIVA  62
            Y    IE+KWQ+ W+++  F T   + K K+YAL MFPYPSG+ LHVGH   Y   DI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRMQGYNVLHPFGYDAFGLPAENAAIAHKIHPKKWTLDNINVIRGQIKKIGISYDWNR  122
            R+KR QG NVLHP G DAFGLPAE+ A+    +P   T +NI  ++ QI+ +G+SYDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVITCTEDYYKWTQWVFLKLYEAGLAYKKPGAVNWCPSCQTVLANEQV-KDGKCERCGTT  181
            EV T   +YYKWTQW+F KLYE GLAY    +VNW     T +ANE+V  DG  ER G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VTMKYLEQWYFKITDYAEKLLEGLDRLPGWPEHVKTMQRNWIGKSTGAEVDFPVDGMDRK  241
            V  K + QW +KIT YAE+LLE+L+ + +WPE +K MQRNWIGKSTGA+V F V + D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  242  IRIFTTRPDTIYGVTFMAIAPESPLVMELVTEDKKKEVEEFLAKVALEDRFKRTSVEAKK  301
            + +FTTRPDT++G T+  +APE +LV  + T D+   V ++  + +L   + RT +   K
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEK  302

Query  302  EGVFLGRYAINPLTNEKIPIYVANYILYEYGTGAIMAVPAHDQRDYDFAKTYNLPIKQVI  361
             GV  G YAINP+    +P+ +A+Y+L  YGTGAIMAVPAHD+RD +FAK +NL I  V+
Sbjct  303  TGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL  362

Query  362  KPKDGEWNINERPYEEEGIMINSGPFDGLESSKGIEEVTKYIEEKGFGKKSVQYKLRDWL  421
                   N++E ++ E+G+ INS+ +DGL+ + +I  +   +E  G G+ +V Y+LRDWL
Sbjct  363  EGG----NVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWL  418

Query  422  ISRQRYWGAPIPIVYCEKCGIVPVPEKDLPVRLPENVEFLP--TGQSPLTLSEEFKHTTC  479
            +SRQRYWG PIPI+  E     +VPE +LP+ LP   ++ P  TG+SPL+   +  + T 
Sbjct  419  FSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTR  478

Query  480  PKCGGPAHREVETMDTFVDSSWYFLRYVNPKLDDKPFESDDVNYWLPVDQYIGGVEHAVL  539
               G  ++RE +TM    +SSWY+LRY++P   +K  + + ++ WLPVD Y+GG EHAVL
Sbjct  479  ED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVL  537

Query  540  HLLYSRFITKVLHDLGYLKFDEPFENLFTQGMI----YKDGW------------------  577
            HLLY+RF  KVL DLG +   EPF++LF QGMI    Y+D++                  
Sbjct  538  HLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFH  597

Query  578  ------------KMSKSKGNVVSPDDMINKYGADTLRMYILFMAPPEKDAEWNDAGIDGV  625
                        KMSKS  NVV+PDD++++YGADTLR+Y +FM+P +    W++ G++G 
Sbjct  598  VETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGS  657

Query  626  NRFIKRLWNNYYKILDIINSNDTknenefgkeeknLRRKLHAMIKKIKEDIEGGFKFNTA  685
             +F+ R+    Y+++   +  +         +   L +  +  +K + E+++   KFNTA
Sbjct  658  RKFLDRV----YRLITTKEITEE--------NSGALDKVYNETVKAVTEQVD-QMKFNTA  704

Query  686  IAGLMEFNNQLSDYLENTKSPNKKLLREIAEKVVLILSPFAPHMAEEMWHDLGKETLIVE  745
            IA LM F         N+ + + KL+ + A   V +++PFAPH++EE+W+ L      + 
Sbjct  705  IAQLMVFV--------NAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESIS  756

Query  746  -EKWPEYDPEALKEDELTIVVQVNGKVRGKITVPADASEEEIKNRAV--ENAGKFLEGKT  802
               WP YD   L E+++ IVVQ++GKV++K+ V+ D S EE+++ A+  E+    + GK 
Sbjct  757  YVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKD  816

Query  803  IVNTIYVKGKLVNIVIK  819
            I++ I V  KLVNIVIK
Sbjct  817  IIKVIAVPNKLVNIVIK  833

831) Haur_4419 in NC_009972


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  569 bits (2150),  Expect = 2e-163, Method: Compositional matrix adjust.
 Identities = 364/849 (43%), Positives = 552/849 (66%), Gaps = 58/849 (6%)

Query  5    YDSSITEPKWRERWERDGIYRFEPDSDKPKHYAVTMLPYPSG-NLHIGHWYAMSPSDVHA  63
            YD +  EPKW+  W  +  ++   D+ KPK YA+ M+PYPSG  LH+GH  + +++D+ +
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYMRMRGYNVFFPMGFDAFGLPAENAAIKNNLDPRKWTYSNIEYMRGQLQSMGMMVDWDQ  123
            R+ R +G NV+ PMG DAFGLPAE+ A+    DP   T  NI   + Q++++G   DWD+
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  QIVSADPEYYRWNQWFFIQFFKRGLAYKKFSAVDWCPKCNTTLAREQVVGDERRCERCDS  183
            ++ ++DP+YY+W QW+F +++ +GLAY    +V+W     T++A E+V+ D    ER + 
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDG-TSERGGY  182

Query  184  LVTKRDLDQWYFKITSYADELL-NFSELDWPERITTMQRNWIGRSEGAEISFK-SEAGDP  241
             V ++ + QW +KIT+YA+ LL ++ E+DWPE I  MQRNWIG+S GA+++FK  +++  
Sbjct  183  PVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  242  ITVFSTRPDTLWGATFMVLAPEHPLVAKLTSAEQKASVDAYVAEAIRKTEVERQSTDDEK  301
            +TVF+TRPDTL GAT+ VLAPEH+LV  +T+++Q  +V  Y  +A  K+++ R  TD  K
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLAR--TDLAK  300

Query  302  PKTGVWIGAYAINPASQERVPIWIADYVLMTYGTGAIMAVPGHDERDFAFAKTFGLAIKR  361
             KTGVW G+YAINP +   +P+WIADYVL +YGTGAIMAVP+HDERD  FAK F L I  
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  362  VVTQSeqtaetpleaaepaYGTVVNSGQIDGLSSAEAKEAVINWLEAEQLGKRAINYRLR  421
            V+  ++    +  E      G  +NS+ +DGL  A A   +++WLEAE +G+  + YRLR
Sbjct  361  VLEGGNVEEAAFTED-----GLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  422  DWLVSRQRYWGTPIPMIYCPTCGTVPVPEDQLPLLLPDSVDFKP--TGESPLKLHPTWRF  479
            DWL SRQRYWG PIP+I      + +VPE +LPL+LP + D++P  TGESPL     W +
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDW-L  474

Query  480  TTCPTCGGEAERDTDTMDTFVDSSWYQVRYLSPHETNAPFTKAIADKWLPVDQYTGGREH  539
                  G  + R+T+TM    +SSWY +RY+ PH+T+      +  +WLPVD Y GG EH
Sbjct  475  EVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEH  534

Query  540  AVMHLLYTRFWWKAMRDMGLVSANEPMTRLINQGVILG----------------------  577
            AV+HLLY+RFW K + D+G+V+++EP  +L+NQG+ILG                      
Sbjct  535  AVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGS  594

Query  578  -----------EDSNKMSKSRGNVIDPDMLVAQYGADTVRTFLMFIGPWEQGGPWNNRGI  626
                       + + KMSKS  NV++PD +V QYGADT+R + MF+GP + + +W++ G+
Sbjct  595  FFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGL  654

Query  627  EGCVRFLDRAWRVVTDTPQRHDAVGDASTLERQTHRIIKKVGDDLQRFAFNTAIAGLMEF  686
            EG  +FLDR  R++T    ++ +  ++++L++  +  +K V +++++  FNTAIA LM F
Sbjct  655  EGSRKFLDRVYRLITT---KEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVF  711

Query  687  VNELMKVRETDVYGTTTWRKATETLTLLLAPIAPHIAEELWEFL-GNSQSVHLQAWPSYD  745
            VN   K  E  +++       +  +  L+AP+APH++EELW+ L ++++S+   +WPSYD
Sbjct  712  VNAANK--EDKLFSDY-----AKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYD  764

Query  746  ETLLIDESIELPVQINGKVRGKIQVAATADEPSIIATALADEKIAPLVAGKTIVKQIVVP  805
            E+ L+++ +E+ VQI+GKV++K+ VA       +   ALA+EK+ + +AGK I+K I VP
Sbjct  765  ESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVP  824

Query  806  NRLVNIVIK  814
            N+LVNIVIK
Sbjct  825  NKLVNIVIK  833

832) leuS in NC_007333


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  569 bits (2148),  Expect = 3e-163, Method: Compositional matrix adjust.
 Identities = 368/853 (44%), Positives = 550/853 (65%), Gaps = 61/853 (7%)

Query  14   YDVRALQEKWQARWAKENPFTASEDPADPRPRRYVLDMFPYPSG-DLHMGHAEAFAIGDV  72
            YD  A++ KWQA WA ++ F ++ D++  +P+ Y LDMFPYPSG +LH+GH+E+++  D+
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDAS--KPKFYALDMFPYPSGAGLHVGHPEGYTATDI  61

Query  73   IARYHFARGENVLHPIGWDSFGLPAENAAIKHNFHPAEWTYTNIETQAESFRRYAISLDW  132
            ++R+  A+G+NVLHP+GWD+FGLPAE+ A+    +PAE T  NI      +   ++S DW
Sbjct  62   LSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDW  121

Query  133  SRRLHTSDPEYYRWNQWFFLRFFERGLAYRKDGLVNWCPKDQTVLANEQVI-QGKCERCG  191
             R ++T+DP+YY+W QW+F +++E+GLAY  +  VNW     T +ANE+V+ +G  ER G
Sbjct  122  DREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGG  181

Query  192  TEVERRALNQWYFKITDYAQRLLDDMEQLEGKWPERVLTMQRNWIGRSEGADVQFTIEGR  251
              V R+++ QW +KIT YA+RLL+D+E+++  WPE +  MQRNWIG+S GA+V F + + 
Sbjct  182  YPVVRKPMRQWMLKITAYAERLLEDLEEVD--WPESIKDMQRNWIGKSTGANVTFKVKDT  239

Query  252  EEPVTVFTTRPDTLYGATFFVVAPDSPLADELCAPEQREAFEAYRTQVSKLSDIERQSTE  311
            +   TVFTTRPDTL+GAT+ V+AP+ +L D + +++Q EA   Y+ Q S  SD+ R    
Sbjct  240  DKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA  299

Query  312  REKTGVFLGRYAINPVNGERIPVWAADYVLADYGHGAIMAVPAHDQRDLDFARKFNLPVR  371
            +EKTGV  G YAINPVNG  +PVW ADYVLA YG GAIMAVPAHD+RD +FA++FNL + 
Sbjct  300  KEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDII  359

Query  372  VVVDTGEPDPAETGIATPGEGTLINSGPLNGLSKSEAIPRIIEILTERGTGKAAVNYRLR  431
             V++ G+ + A    A   +G  INS+ L+GL K+ AI++++E L   G G+  V YRLR
Sbjct  360  PVLEGGNVEEA----AFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  432  DWLVSRQRFWGTPIPIIHCPECGEVPVPDEELPVRLPDLRGAALAPKGVSPLAAATDWVN  491
            DWL SRQR+WG PIPIIH  +    +VP+ ELP+ LP  ++   +  G SPLA  TDW++
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  492  VSCPRCGGPAKRDTDTMDTFVDSSWYFLRYCSPNLDTAPFDQEKVAKWGPIDQYVGGVEH  551
            V+    G  ++R+T+TM    +SSWY+LRY  P+      D+E + +W P+D YVGG EH
Sbjct  476  VTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEH  534

Query  552  AILHLLYSRFFTKVLYDMGMVPFTEPFVRLLNQGQVINQG--------------------  591
            A+LHLLY+RF  KVLYD+G+VP  EPF +L+NQG ++  +                    
Sbjct  535  AVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGS  594

Query  592  --------------KAMSKSLGNGVDLGQEIDRYGVDAVRLTMVFAGPPEEDIDWADVSP  637
                            MSKSL N V+ ++ +++YG D++R+  +F GP +  I W++ + 
Sbjct  595  FFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGL  654

Query  638  GASVKFLNRAYRVMaeaaaasaPGVDPATGDLALRRMTHQTLAKVTEAVEAQRFNVAIAR  697
             +S KFL+R YR+++          +  +G  AL ++ ++T+  VTE V+  +FN AIA+
Sbjct  655  EGSRKFLDRVYRLITTKEI-----TEENSG--ALDKVYNETVKAVTEQVDQMKFNTAIAQ  707

Query  698  IMELVTAARRAIDSGPGAADPAVREAAEVIAITLGLFAPYVAEEGWEMLGHTG-SVSVGT  756
            +M +V AA +         D    + A  +   ++ FAP ++EE W+ L  +G S+S   
Sbjct  708  LMVFVNAANK--------EDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVP  759

Query  757  WREPDPALLVQESVTCVVQVASKVRDKLQVSPDISaeelerlalaSEKVQNHIAGREIRR  816
            W   D + LV++ V  VVQ+ +KV+ KL V+ D+S EEL+ +ALA+EKVQ +IAG++I +
Sbjct  760  WPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIK  819

Query  817  IVVREPKLVNIVV  829
            ++    KLVNIV+
Sbjct  820  VIAVPNKLVNIVI  832

833) Cyagr_0582 in NC_019675


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  569 bits (2147),  Expect = 3e-163, Method: Compositional matrix adjust.
 Identities = 372/872 (43%), Positives = 561/872 (65%), Gaps = 49/872 (5%)

Query  7    YRPEAIEQRWQLQWEQLGLHATPDPHDAAGEPYYTLSMFPYPSGS-LHMGHVRNYVITDV  65
            Y   AIE +WQ  W +   H+     DA+   +Y+L MFPYPSG+ LH+GH   Y  TD+
Sbjct  4    YDHTAIEPKWQAFWADN--HTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDI  61

Query  66   IARAARLRGRQVLHPMGWDAFGLPAENAAIERGVDPGDWTDRNIAQMRDQLKRLGLSIDW  125
            ++R  R +G++VLHPMGWDAFGLPAE+ A++ G DP++ T  NIA+ + Q++ LG+S DW
Sbjct  62   LSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDW  121

Query  126  DREVATCHADYYRWTQWLFLQFLDAGLAYRKEATVNWDPIDQTVLANEQVDAEGRSWRSG  185
            DREV T +++YY+WTQW+F ++ + GLAY  E  VNW     T +ANE+V ++G S R+G
Sbjct  122  DREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGG  181

Query  186  AQVEKRRLRQWFLKITAYADALLDDLPTLEGWPERVRTMQANWIGRSLGAELTFTT-ESG  244
              V ++ +RQW LKITAYA+ LL+DL  ++ WPE ++ MQ NWIG+S GA++TF   +++
Sbjct  182  YPVVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  245  AAITVFTTRPDTIHGATYVVLAPDHPLVAELTTDDCRLSVTAFCDLVSRQSEQERTAEDR  304
              +TVFTTRPDT+ GATY VLAP+H+LV  +TT D   +V+ +    S +S+  RT   +
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  305  PKRGVPIGAWARNPASGERIPVWIADYVLADYGTGAVMGVPAHDQRDFAFARQYELPVRR  364
             K GV  G+ A NP +G  +PVWIADYVLA YGTGA+M+VPAHD+RD  FA+Q++L +  
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  365  VVIPEGSDPHAYEGQAWTESGVLIGSGSFDGLTTTEAKSAIVAWAEEQGWGQGRVQYRLR  424
            V+     +  A+     TE G+ I S+ +DGL  + A + +V W E +G G+  V YRLR
Sbjct  361  VLEGGNVEEAAF-----TEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  425  DWLISRQRYWGCPIPVIHCDSCGVVPVPDDQLPVELP--RDIPLSGKGGTPLAKLASWVN  482
            DWL+SRQRYWG PIP+IH +     +VP+ +LP+ LP  +DI  SG G +PLA+++ W++
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  483  VPCPSCGAPAKRETDTMDTFMCSSWYYLRYSDPHNDQRPFERPAVDRWLPVDQYVGGIEH  542
            V     G  ++RET+TM     SSWYYLRY DPHN ++  +   + +WLPVD YVGG EH
Sbjct  476  VTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEH  534

Query  543  AILHLLYSRFFTKVLRDRGLLGFSEPFARLLTQGMVQGITYRNPQTGQYVAPAQVADPSD  602
            A+LHLLY+RF  KVL D G++   EPF +L+ QGM+ G +YR+++ G  VA  +V    +
Sbjct  535  AVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSR-GALVATDKVEKRDG  593

Query  603  PRDPV-SGEVLEVFYEKMSKSKHNGVDPAVVIDRYGADTARMFILFKAPPEKDLEWDDAD  661
            +   V +GE LE    KMSKS  N V+P  V+++YGADT R++ +F +P +  + W + +
Sbjct  594  SFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEG  653

Query  662  VEGQYRFLQRLWRLVDAAHGRGLRLSGPEAPQPVSADAASLSDGERELRRAVHTAIAAIS  721
            +EG  +FL+R+ RL+              + + ++ + ++       L +  + ++ A++
Sbjct  654  LEGSRKFLDRVYRLI--------------TTKEITEENSG------ALDKVYNETVKAVT  693

Query  722  EDLEGELQLNTAVSELMKLSNALAAHLEGAGPavatealatllillaPFAPHLAEELWQK  781
            E+++ ++++NTA+++LM + NA           + ++    ++ L+APFAPHL+EELWQ 
Sbjct  694  EQVD-QMKFNTAIAQLMVFVNA-----ANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  782  LCGHGEEQPISAGASVHAQRWPAVDAAALVRDTIPLVIQVKGKMRGSLEVPADADAATLE  841
            L + GE        S+    WP+ D + LV + + +V+Q+KGK+++ L V+ D     L+
Sbjct  748  LTASGE--------SISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQ  799

Query  842  KLALESEVAQRWLEGQPPRRVIVVPGKLVNLV  873
             +AL +E  Q  + G+   +VI VP KLVN+V
Sbjct  800  EVALANEKVQAEIAGKDIIKVIAVPNKLVNIV  831

834) Asphe3_19760 in NC_015145


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  568 bits (2145),  Expect = 6e-163, Method: Compositional matrix adjust.
 Identities = 355/855 (42%), Positives = 541/855 (64%), Gaps = 66/855 (7%)

Query  25   YSFAAMEAKWPQVWEDLKVFTPVDDGSRERRYVLDMFPYPSG-DLHMGHAEAFAMGDVVA  83
            Y  +A+E+KW   W D   F    D+S+ + Y LDMFPYPSG +LH+GH+E+++  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  84   RYLRQKGYDVLHPIGWDSFGLPAENAAIKRNAHPSEWTYANIDTQAASFKRYAISADWSR  143
            R+ R +G +VLHP+GWD+FGLPAE+ A+    +P+E T  NI      ++  ++S DW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  144  RLHTSDPEYYRWTQWLFKRFYERGLAYRKNSPVNWCPKDQTVLANEQVV-NGACERCGTT  202
             ++T+DP+YY+WTQW+F ++YE+GLAY  + PVNW     T +ANE+V+ +G+ ER G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  203  VTKKSLNQWYFKITEYADRLLDDMEQLRGHWPERVLAMQKNWIGRSEGAHVNFVIEADGG  262
            V +K++ QW +KIT YA+RLL+D+E++  +WPE +  MQ+NWIG+S GA+V F +     
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV--DWPESIKDMQRNWIGKSTGANVTFKVKD---  238

Query  263  KPAKEVTVFTTRPDTLYGATFFVVAADAPLAVELVTEEHAAALDEYREQVKALSEIERQS  322
               K+ TVFTTRPDTL+GAT+ V+A++ +L   + T ++A A+ +Y+ Q    S++ R  
Sbjct  239  -TDKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTD  297

Query  323  TEREKTGVFTGRYAINPLNGEKLQVWAADYVLADYGTGAIMAVPAHDQRDLDFARTFDLP  382
              +EKTGV TG YAINP+NG  + VW ADYVLA YGTGAIMAVPAHD+RD +FA+ F+L 
Sbjct  298  LAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLD  357

Query  383  VRAVLDTGEEDPAVSGTATAGEGTLVNSGELDGLPKAEAIPAAIAMLERQGTGEKFVNFR  442
            + +VL+ G+    V  +A + +G  +NS+ LDGL KA AI+  +  LE +G G+  V +R
Sbjct  358  IIPVLEGGN----VEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYR  413

Query  443  LRDWLLSRQRFWGTPIPIIHCPSCGEVPVPDEQLPVTLP--SDLRGEDLAPKGTSPLAAA  500
            LRDWL+SRQR+WG PIPIIH       +VP+ +LP+ LP   D+R    +  G SPLA  
Sbjct  414  LRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRP---SGTGESPLANV  470

Query  501  EAWVNVECPSCHGPAKRDTDTMDTFVDSSWYFLRFVSPHYTEGPFDPQKINDWMPVGQYV  560
              W++V        ++R+T+TM    +SSWY+LR++ PH TE   D + +++W+PV+ YV
Sbjct  471  TDWLEVTREDG-VKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYV  529

Query  561  GGVEHAILHLLYARFFTKVIHDLGLIETSEPFTALLNQGQVLNGG---------------  605
            GG EHA+LHLLYARF  KV+ DLG++ T EPF  L+NQG +L  +               
Sbjct  530  GGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVE  589

Query  606  -------------------KAMSKSLGNGVDLGEQLDKYGVDAVRLTMIFASPPEDDVDW  646
                                 MSKSL N V+ ++ +++YG D++R+  +F +P +  + W
Sbjct  590  KRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAW  649

Query  647  ADVSPSGSAKFLARAWRLAQDVASEPGVDVTTGDRGLRSITHRTIADAAELLDANKFNVV  706
            ++ +  GS KFL R  RL   +++    +  +G  +L  + + T+   +E +D  KFN  
Sbjct  650  SEEGLEGSRKFLDRVYRL---ITTKEITEENSG--ALDKVYNETVKAVTEQVDQMKFNTA  704

Query  707  VAKLMELVNATRKAIDagaggaDPavreaaeavavILSLFAPYTAEDMWSVLGHPA-SVA  765
            +A+LM +VNA+ K         D    + A +   +++ FAP  +E++W  L  ++ S++
Sbjct  705  IAQLMVFVNAANKE--------DKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESIS  756

Query  766  NAGWPVHDPSLLVQDSVTAVVQVQGKVRDRLEVSPSVSEDQLRELALASENVQRALDGRG  825
               WP  D S LV++ V  VVQ++GKV+ +L V+  +S ++L+E+ALA+E+VQ  + G++
Sbjct  757  YVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKD  816

Query  826  IRTVIVRAPKLVNIV  840
            I  VI  + KLVNIV
Sbjct  817  IIKVIAVPNKLVNIV  831

835) leuS in NC_008820


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  568 bits (2144),  Expect = 7e-163, Method: Compositional matrix adjust.
 Identities = 373/868 (43%), Positives = 569/868 (66%), Gaps = 48/868 (5%)

Query  18   YDPIELETRWQKEWLRQGLDRTPVAETNQKRFYALSMFPYPSGK-LHMGHVRNYVITDVI  76
            YD   +E +WQ  W  +   +T  +++++ +FYAL MFPYPSG  LH+GH   Y  TD++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTG-TDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDIL  62

Query  77   ARVQRMRGDAVLHPMGWDAFGLPAENAAIARNVDPGDWTDQNIAQMRAQLDRLGLSIDWD  136
            +R +R +G+ VLHPMGWDAFGLPAE+ A+    DP++ T +NIA+ + Q++ LG+S DWD
Sbjct  63   SRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWD  122

Query  137  RQQATCHQDYYRWTQWLFLELFAGGLAYQKEATVNWDPIDKTVLANEQVDGEGRSWRSGA  196
            R+  T + +YY+WTQW+F  L+  GLAY+ E  VNW     T +ANE+V  +G S R+G 
Sbjct  123  REVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGY  182

Query  197  LVEQRQLKQWFLRITDYADALIDDLDELTGWPERVRTMQANWIGRSHGAEIKFRVAGQTN  256
             V ++ ++QW L+IT YA+ L++DL+E+ +WPE ++ MQ NWIG+S GA++ F+V  +T+
Sbjct  183  PVVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVK-DTD  240

Query  257  SIITVFTTRPDTLHGASYVVLAPEHPLVEALTSPQQRIAVTAF---CDLISQLSVKDRTA  313
              +TVFTTRPDTL GA+Y VLAPEH+LV+A+T+++Q  AV+ +     L S+L+   RT 
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLA---RTD  297

Query  314  EDQPKRGVPIGAQVINPVNGESLPVWIADYVLADYGSGAVMGVPAHDERDFIFARSHELP  373
              + K GV  G+  INPVNG  +PVWIADYVLA YG+GA+M+VPAHDERD  FA+  +L 
Sbjct  298  LAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLD  357

Query  374  IRIVVQMPDSDEHHNDGQAWTGAGVLVNSGAFDGLSTEEGKVAITTHGASKGWAQSKVQY  433
            I  V++  + +E      A T  G+ +NS+ +DGL    +   +     + G ++ +V Y
Sbjct  358  IIPVLEGGNVEE-----AAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTY  412

Query  434  RLRDWLISRQRYWGCPIPIIHCASCGIVPVPQEDLPVTLP--RDIDLSGKGGSPLAQEQD  491
            RLRDWL+SRQRYWG PIPIIH       +VP+ +LP+ LP  +DI  SG G SPLA+  D
Sbjct  413  RLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTD  472

Query  492  WVEVKCPICGEKAHRETDTMDTFMCSSWYYLRFADPLNSQRPFDKDIVDEWLPVDQYVGG  551
            W+EV     G K++RET+TM     SSWYYLR+ DP N+++  D +++ +WLPVD YVGG
Sbjct  473  WLEVTRE-DGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGG  531

Query  552  IEHAILHLLYARFFTKALHDRNLIGFKEPFNTLLTQGMVQGLTYRNTKNGSYISPELVSD  611
             EHA+LHLLYARF  K L D  ++  KEPF+ L+ QGM+ G +YR+++ +   +  +   
Sbjct  532  AEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKR  591

Query  612  EGDPRDPESGDKLEILFEKMSKSKYNGVDPAVVIDRYGADTARMFILFKAPPEKDLEWDD  671
            +G   + E+G+ LE    KMSKS  N V+P  V+++YGADT R++ +F +P +  + W +
Sbjct  592  DGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSE  651

Query  672  ADVEGQFRFLQRLIRLIDSFVWPKTDEDNASISSANLTISSADLSEEEIN-MRRATHMAI  730
             ++EG  +FL+R+ RL                      I++ +++EE+   + +  + ++
Sbjct  652  EGLEGSRKFLDRVYRL----------------------ITTKEITEENSGALDKVYNETV  689

Query  731  EAITEDLSGDIQLNTAISELMKLSNSLGGKLDKVRTEVAAEALSVLVRLMAPFAPHLAEE  790
             A+TE++ +++++NTAI++LM + N+ + K DK+ ++ A      +V+L+APFAPHL+EE
Sbjct  690  KAVTEQV-DQMKFNTAIAQLMVFVNA-ANKEDKLFSDYAKG----FVQLIAPFAPHLGEE  743

Query  791  FWMKLHGQG-SIHQQSWPIIDPSALVLETIELVIQVKGKVRGTIQVPANADKTALEELAL  849
            +W  L + G SI   +WP  D S LV + +E+V+Q+KGKV++ + V+ +  +  L+E+AL
Sbjct  744  LWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVAL  803

Query  850  KSDIAVKWLEGQSPRRVIIVPGKLVNLV  877
             ++     + G+   +VI VP KLVN+V
Sbjct  804  ANEKVQAEIAGKDIIKVIAVPNKLVNIV  831

836) leuS in NC_016829


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  567 bits (2141),  Expect = 1e-162, Method: Compositional matrix adjust.
 Identities = 380/843 (46%), Positives = 553/843 (66%), Gaps = 69/843 (8%)

Query  2    YNHLKIEQKWQKYWQQNKTFKT-TNHHLQKFYVLDMFPYPSASGLHIGHPLGYTATDIIA  60
            Y+H  IE KWQ +W +N TFKT T+    KFY LDMFPYPS++GLH+GHP GYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  61   RFKRLNNFDVLHPIGWDAFGLPAEQYALSTKNHPAKFTQENIQNFKKQLISLGFSYDWDK  120
            RFKR +  +VLHP+GWDAFGLPAEQYA+ T N+PA FT ENI NFK+Q+ +LGFSYDWD+
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  121  EVDTTDPLFYEQTQKIFALLYKHNLAEIREVEVNWCPELATvlaneevlvneeGQLVSER  180
            EV+TTDP +Y  TQ IF+ LY   LA   EV VNW  EL+T         +   +  SER
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGT----AIANEEVLPDGTSER  179

Query  181  GGFLVYPKKMKQWVLKITQYADRLLEDLKLVNFPSSLKSLQENWIGKSLGWNVKFKLQDK  240
            GG+ V  K M+QW+LKIT YA+RLLEDL  V+ P S+K +Q NWIGKS G NV FK++D 
Sbjct  180  GGYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDT  239

Query  241  QKDVDIFTTRLDTIFGATFLAISPNHWLAEEL--ANQNPAIKTFIENFAARE----KQKN  294
            +KD  +FTTR DT+FGAT+  ++P+H L + +  ++Q  A+  +  + + +      +  
Sbjct  240  DKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA  299

Query  295  NSKTGIATNLFAINPVNNKEIPIFICDYVIANYQTGALMGVPSHDERDKEFALLNNIEFI  354
            + KTG+ T  +AINPVN KE+P+ I DYV+A+Y TGA+M+VP+HDERD EFA   N+++I
Sbjct  300  KEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDII  359

Query  355  EVINE---------KERLINSKKY-NNLTIFQARAHIHFDLKNEGKSSQVKAFKIKDWVF  404
             V++           + L  +  + + L    A A +   L  EG +++  +++++DW+F
Sbjct  360  PVLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLF  419

Query  405  SRQRYWGEPFP-IYFDEDGKIYLEEKLVE--LPYMENITPSGDGQSPLANNKSWVFFEKE  461
            SRQRYWGEP+P I  +++    + E  +   LP   +I PSG G+SPLAN   W+   +E
Sbjct  420  SRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRE  479

Query  462  -GKKYRRETNTMPQWAGSSWYFLAYILKNADGSYLDIESKEAYQRFEKWMPVDLYIGGQE  520
             G K RRETNTMPQWAGSSWY+L YI  +      D E       + +W+PVD+Y+GG E
Sbjct  480  DGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEEL------LKQWLPVDIYVGGAE  533

Query  521  HAVGHLIYSRFWYKFLYDLKIVPTKEPFYKVVNQGMLLGTD-------------------  561
            HAV HL+Y+RFW K LYDL +VPTKEPF K+ NQGM+LGT                    
Sbjct  534  HAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDG  593

Query  562  --------------GQKMSKSKGNIINPNEVVNQFGADSLRIYLMFMSPLIDTKAWSVEG  607
                            KMSKS  N++NP++VV+Q+GAD+LR+Y MFM+PL  + AWS EG
Sbjct  594  SFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEG  653

Query  608  IQGIKKWVDRIVRIMQKSFIYEENYSNAEFESIYHQSIKEIGENIEALKYNIAISKMMVY  667
            ++G +K +DR+ R++    I EEN  ++ ++ +Y++++K + E+++ +K+N AI+++MV+
Sbjct  654  LEGSRKFLDRVYRLITTKEITEEN--SGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVF  711

Query  668  INHLYKQEILSSKKYLVDFLIMFSTFAPHIAEELLEQLEQK--PIHLQQWPTFDQSKILS  725
            +N   K++ L S  Y  +F+ +++ FAPH++EEL + L     +I    WP++D+SK++ 
Sbjct  712  VNAANKEDKLFS-DYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVE  770

Query  726  NIVNIAVQVNGKLRAIIQKNDEDSKEDILNKAKSNENVLKYIQNKDIVKEIYIKDKIVTL  785
            N V+I VQ++GK++A +    + S+E++ + A +NE+V   I  KDI+K I + +K+V +
Sbjct  771  NDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNI  830

Query  786  VVK  788
            V+K
Sbjct  831  VIK  833

837) leuS in NC_017519


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  567 bits (2141),  Expect = 1e-162, Method: Compositional matrix adjust.
 Identities = 380/843 (46%), Positives = 553/843 (66%), Gaps = 69/843 (8%)

Query  2    YNHLKIEQKWQKYWQQNKTFKT-TNHHLQKFYVLDMFPYPSASGLHIGHPLGYTATDIIA  60
            Y+H  IE KWQ +W +N TFKT T+    KFY LDMFPYPS++GLH+GHP GYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  61   RFKRLNNFDVLHPIGWDAFGLPAEQYALSTKNHPAKFTQENIQNFKKQLISLGFSYDWDK  120
            RFKR +  +VLHP+GWDAFGLPAEQYA+ T N+PA FT ENI NFK+Q+ +LGFSYDWD+
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  121  EVDTTDPLFYEQTQKIFALLYKHNLAEIREVEVNWCPELATvlaneevlvneeGQLVSER  180
            EV+TTDP +Y  TQ IF+ LY   LA   EV VNW  EL+T         +   +  SER
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGT----AIANEEVLPDGTSER  179

Query  181  GGFLVYPKKMKQWVLKITQYADRLLEDLKLVNFPSSLKSLQENWIGKSLGWNVKFKLQDK  240
            GG+ V  K M+QW+LKIT YA+RLLEDL  V+ P S+K +Q NWIGKS G NV FK++D 
Sbjct  180  GGYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDT  239

Query  241  QKDVDIFTTRLDTIFGATFLAISPNHWLAEEL--ANQNPAIKTFIENFAARE----KQKN  294
            +KD  +FTTR DT+FGAT+  ++P+H L + +  ++Q  A+  +  + + +      +  
Sbjct  240  DKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA  299

Query  295  NSKTGIATNLFAINPVNNKEIPIFICDYVIANYQTGALMGVPSHDERDKEFALLNNIEFI  354
            + KTG+ T  +AINPVN KE+P+ I DYV+A+Y TGA+M+VP+HDERD EFA   N+++I
Sbjct  300  KEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDII  359

Query  355  EVINE---------KERLINSKKY-NNLTIFQARAHIHFDLKNEGKSSQVKAFKIKDWVF  404
             V++           + L  +  + + L    A A +   L  EG +++  +++++DW+F
Sbjct  360  PVLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLF  419

Query  405  SRQRYWGEPFP-IYFDEDGKIYLEEKLVE--LPYMENITPSGDGQSPLANNKSWVFFEKE  461
            SRQRYWGEP+P I  +++    + E  +   LP   +I PSG G+SPLAN   W+   +E
Sbjct  420  SRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRE  479

Query  462  -GKKYRRETNTMPQWAGSSWYFLAYILKNADGSYLDIESKEAYQRFEKWMPVDLYIGGQE  520
             G K RRETNTMPQWAGSSWY+L YI  +      D E       + +W+PVD+Y+GG E
Sbjct  480  DGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEEL------LKQWLPVDIYVGGAE  533

Query  521  HAVGHLIYSRFWYKFLYDLKIVPTKEPFYKVVNQGMLLGTD-------------------  561
            HAV HL+Y+RFW K LYDL +VPTKEPF K+ NQGM+LGT                    
Sbjct  534  HAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDG  593

Query  562  --------------GQKMSKSKGNIINPNEVVNQFGADSLRIYLMFMSPLIDTKAWSVEG  607
                            KMSKS  N++NP++VV+Q+GAD+LR+Y MFM+PL  + AWS EG
Sbjct  594  SFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEG  653

Query  608  IQGIKKWVDRIVRIMQKSFIYEENYSNAEFESIYHQSIKEIGENIEALKYNIAISKMMVY  667
            ++G +K +DR+ R++    I EEN  ++ ++ +Y++++K + E+++ +K+N AI+++MV+
Sbjct  654  LEGSRKFLDRVYRLITTKEITEEN--SGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVF  711

Query  668  INHLYKQEILSSKKYLVDFLIMFSTFAPHIAEELLEQLEQK--PIHLQQWPTFDQSKILS  725
            +N   K++ L S  Y  +F+ +++ FAPH++EEL + L     +I    WP++D+SK++ 
Sbjct  712  VNAANKEDKLFS-DYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVE  770

Query  726  NIVNIAVQVNGKLRAIIQKNDEDSKEDILNKAKSNENVLKYIQNKDIVKEIYIKDKIVTL  785
            N V+I VQ++GK++A +    + S+E++ + A +NE+V   I  KDI+K I + +K+V +
Sbjct  771  NDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNI  830

Query  786  VVK  788
            V+K
Sbjct  831  VIK  833

838) leuS in NC_020291


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  567 bits (2141),  Expect = 1e-162, Method: Compositional matrix adjust.
 Identities = 380/848 (45%), Positives = 557/848 (66%), Gaps = 58/848 (6%)

Query  6    TKIDAKWQKIWEENETYKFNTENLDKKLYTLEMFSYPSGAQLHAGHWFNYGPTDSWARLK  65
            T I++KWQ +W +N+T+K  T+    K+Y+L+MF+YPSGA LH GH   Y +TD  +R+K
Sbjct  7    TAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSRFK  66

Query  66   RMQGYNVFQPMGFDAFGLPAENYAIKTGIHPQDSTLKNIETMEKQLKSMGAMFNWENEVV  125
            R QG NV++PMG DAFGLPAE+YA+ TG +P + T  NI    +Q++++G  ++W+ EV 
Sbjct  67   RAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDREVN  126

Query  126  TCLPDYYKWTQWLFLKLYEKGLAYRKKAPVNWCPSCNTVLANEQVV-DGACERCSTEVTK  184
            T  P+YYKWTQW+F KLYEKGLAY    PVNW     T +ANE+V+ DG+ ER +  V +
Sbjct  127  TTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVR  186

Query  185  KDLTQWFFKITdygdelldklddldWPEKTKSMQKHWIGRSYGAQVTFKVKDSDLKFDVF  244
            K + QW +KIT Y++ LL+ L+++DWPE  K MQ++WIG+S GA+VTFKVKD+D  F VF
Sbjct  187  KPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVF  246

Query  245  TTRVDTLNGVTYVVLAPENKLVDKLTLPeykaaveeykeaaakQSEIERQSNTKEKTGVF  304
            TTR DTL G TY VLAPE+ LVD +T ++   AV +YK  A+ +S++ R   +KEKTGV 
Sbjct  247  TTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVW  306

Query  305  TGAYAINPINGKVVPIWISDYVLATYGTGCVMAVPAHDERDFAFATKFNLPIERVITDKD  364
            TG+YAINP+NGK +P+WI+DYVLA+YGTG +MAVPAHDERD  FA +FNL I  V+ + +
Sbjct  307  TGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGN  366

Query  365  NTDPELPYCEYGVLVNSGKFDGLTTEEAKKKIVEDLEKDELGQMKINFRLRDWLVSRQRY  424
              ++  ++ E G+ +NS+ +DGL    A  K+VE LE + +G+ ++ +RLRDWL SRQRY
Sbjct  367  VEEA--AFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRY  424

Query  425  WGAPIPIIYCETCGIVPVPEKDLPVELPYNVEFTPDGK--SPLGKSEEFVNTTCPCCGKP  482
            WG PIPII  E     +VPE +LP+ LP   ++ P G   SPL++  + ++ T     K 
Sbjct  425  WGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK-  483

Query  483  AKREADTLDTFVCSSWYYLRYADNKNADAPFDPEKINKILPVDKYVGGPEHACMHLLYAR  542
            ++RE++T+     SSWYYLRY D  N++   D E +++ LPVD YVGG+EHA +HLLYAR
Sbjct  484  GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYAR  543

Query  543  FITKALRDMGYLNFDEPFLSLTHQGLILGP----------------------------DG  574
            F  K L D+G +   EPF  L +QG+ILG                             + 
Sbjct  544  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEE  603

Query  575  L-----KMSKSKGNTISPDDYIKEYGADVFRMYLMFGFGYTEGGAWSDDGIKSVGKFVDR  629
            L     KMSKS  N ++PDD + +YGAD +R+Y MF      + AWS++G+ +  KF+DR
Sbjct  604  LEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR  663

Query  630  IERILDTCRAIIDSNENVKDSIDSAEKELNFWKHTAIRGVTEDGDKMQFNTAIARLMELT  689
            + R++ T + I + N    D +        +  + ++++VTE+ D+M+FNTAIA+LM   
Sbjct  664  VYRLI-TTKEITEENSGALDKV--------Y--NETVKAVTEQVDQMKFNTAIAQLMV--  710

Query  690  NALNKYTQENVKNANFLKATITDFVKLLAPFAPHFAEEQW-SLLGNTSTIFNESFPEFDP  748
                 + +   K+ +++     +FV+L+APFAPH++EE W +L ++  +I   + P +D 
Sbjct  711  -----FVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDE  765

Query  749  SALVKDEVEIAIQINGKIKSKIMVASNLDEEGIKAASLENETIKENTEGKNIVKVIVIKG  808
            S LV ++VEI +QI+GK+K+K++VA +L  E ++  +L NE ++ +  GK+I+KVI +  
Sbjct  766  SKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPN  825

Query  809  RLVNIVVK  816
            +LVNIV+K
Sbjct  826  KLVNIVIK  833

839) Dehly_1143 in NC_014314


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  567 bits (2141),  Expect = 1e-162, Method: Compositional matrix adjust.
 Identities = 374/850 (44%), Positives = 550/850 (65%), Gaps = 60/850 (7%)

Query  6    YEPQAIESKWQKRWADDGLYRVDEDSPKPKWYALTMFPYTSG-DLHIGHWYAMAPSDAYA  64
            Y+  AIE+KWQ  WAD+  ++ + D++KPK YAL MFPY SG +LH+GH  + +++D  +
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  65   RYKRMQGYNVLHPMGFDAFGLPAENAAIKRGIHPREWTMKNVENMRKQIKSMGSVYDWDR  124
            R+KR QG NVLHPMG DAFGLPAE+ A+  G +P E T  N+ N ++QI+++G  YDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  125  EVITCLPEYYKWTEWFFLKLYQAGLAYRAKAPVNWCASCQTVLANEQVVGNGECERCEGP  184
            EV T  P+YYKWT+W+F KLY+ GLAY A  PVNW     T +ANE+V+ +G  ER   P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  185  VEKRDLEQWFFRVTKYADELMDH-EGLDWPERIKTMQRNWVGRSTGAEIEFGLDAPGVEE  243
            V ++ + QW +++T YA+ L+++ E +DWPE IK MQRNW+G+STGA++ F +      +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDT---D  240

Query  244  KRLKVFTTRPDTVYGVTFMVLAPEHPLVAKLTTPEQSEAVEAYVARTRRLTEIDRLSTEK  303
            K + VFTTRPDT++G T+ VLAPEH+LV  +TT++Q+EAV  Y  ++   +++ R    K
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  304  EKDGVFTGAYVENLLNGEKVPVWIADYVIASYGSGAVMAVPAHDERDFAFAQKYSLPVRV  363
            EK GV TG+Y  N +NG  +PVWIADYV+ASYG+GA+MAVPAHDERD  FA++++L +  
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  364  VVAPEDYRGGPIAEAH-TAEGVMVNSAQFNGLTNTEAFGGICDWMEAQGFGRRTVSYKLR  422
            V+      GG + EA  T +G+ +NS  ++GL ++ A++ + +W+EA+G G   V+Y+LR
Sbjct  361  VLE-----GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  423  DWLISRQRYWGAPIPMIYCDKCGIVPVPEKDLPVLLPDNAEFRP--TGESPLKYAEDFVN  480
            DWL+SRQRYWG PIP+I  +     +VPE +LP++LP   ++RP  TGESPL    D ++
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  481  TTCPACGGPARRETDTMDTFMCSSWYYLRYCSPHDDKHAFDPEKTRYWMPVDIYTGGAEH  540
             T    G  +RRET+TM     SSWYYLRY  PH+     D E  + W+PVDIY GGAEH
Sbjct  476  VTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEH  534

Query  541  AVMHLFYSRFFVKALRDMGLVDFSEPFTRLFNQGTITS----------------------  578
            AV+HL+Y+RF  K L D+G+V   EPF +LFNQG I +                      
Sbjct  535  AVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGS  594

Query  579  ------------QHAKMSKSRGNVVNPDRYVNEQGADTVRAYLMFVGPWELGGDWNDSGI  626
                          AKMSKS  NVVNPD  V++ GADT+R Y MF+GP + +  W++ G+
Sbjct  595  FFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGL  654

Query  627  GGISRWFNRVWKLATEPYQPGGFDEEAEAELIRHTHQTVRKVNTDLDALQFNTMLAALME  686
             G  + ++RV +L T       + EE  + L +  ++TV+ V  ++D ++FNT +A LM 
Sbjct  655  EGSRKFLDRVYRLIT----TKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMV  710

Query  687  FTNYLGPAKDSGKVSAETWKDAVNKLILMLAPTAPHLAEELWE-LTGHEYSVHNQQFPTW  745
            F N   +A+  +K+ ++      + ++ ++AP APHL+EELW+ LT+   S+     P+ 
Sbjct  711  FVN---AANKEDKLFSDY----AKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSY  763

Query  746  QEELTAEPEITLVVQVNGKLRARIPAPADLTESSALGLADANERIREYTKGKTTVKIVYV  805
            +E    E ++ +VVQ++GK++A++  + DL+      +A ANE+++    GK  +K++ V
Sbjct  764  DESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAV  823

Query  806  PGKLLNIVVK  815
            P KL+NIV+K
Sbjct  824  PNKLVNIVIK  833

840) leuS in NC_005071


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  567 bits (2141),  Expect = 1e-162, Method: Compositional matrix adjust.
 Identities = 370/868 (43%), Positives = 568/868 (66%), Gaps = 48/868 (5%)

Query  18   YDPIELETRWQKEWLRQGLDRTPVAETNQKRFYALSMFPYPSGK-LHMGHVRNYVITDVI  76
            YD   +E +WQ  W  +   +T  +++++ +FYAL MFPYPSG  LH+GH   Y  TD++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTG-TDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDIL  62

Query  77   ARVQRMRGDAVLHPMGWDAFGLPAENAAIARNVDPGDWTDQNIAQMRAQLDRLGLSIDWD  136
            +R +R +G+ VLHPMGWDAFGLPAE+ A+    DP++ T +NIA+ + Q++ LG+S DWD
Sbjct  63   SRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWD  122

Query  137  RQQATCHQDYYRWTQWLFLELFAGGLAYQKEATVNWDPVDKTVLANEQVDGEGRSWRSGA  196
            R+  T + +YY+WTQW+F  L+  GLAY+ E  VNW     T +ANE+V  +G S R+G 
Sbjct  123  REVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGY  182

Query  197  LVEQRQLKQWFLRITDYADALIDDLDELTGWPERVRTMQANWIGRSHGAEIKFRVAGVAN  256
             V ++ ++QW L+IT YA+ L++DL+E+ +WPE ++ MQ NWIG+S GA++ F+V +  +
Sbjct  183  PVVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDK  241

Query  257  SIITVFTTRPDTLHGASYVVLAPEHPLVESLTSPEQRLAVTAF---CDLISQLSVKDRTA  313
             + TVFTTRPDTL GA+Y VLAPEH+LV+++T+++Q  AV+ +     L S+L+   RT 
Sbjct  242  DF-TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLA---RTD  297

Query  314  EDQPKRGVPIGAQVINPVNGESLPVWIADYVLADYGSGAVMGVPAHDERDFIFARSHELP  373
              + K GV  G+  INPVNG  +PVWIADYVLA YG+GA+M+VPAHDERD  FA+  +L 
Sbjct  298  LAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLD  357

Query  374  IRIVVQLPDTDEHHNDGQAWTGAGVLVNSGAFDGLSTEEAKVAITTHGASEGWAQSKVQY  433
            I     +P  +  + +  A T  G+ +NS+ +DGL    A   +     +EG ++ +V Y
Sbjct  358  I-----IPVLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTY  412

Query  434  RLRDWLISRQRYWGCPIPIIHCASCGIVPVPQEDLPVTLP--RDIDLSGKGGSPIAQEQA  491
            RLRDWL+SRQRYWG PIPIIH       +VP+ +LP+ LP  +DI  SG G SP+A+   
Sbjct  413  RLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTD  472

Query  492  WVEVKCPICGEKAHRETDTMDTFMCSSWYYLRFADPLNSQRPFDKDIVDEWLPVDQYVGG  551
            W+EV     G K++RET+TM     SSWYYLR+ DP N+++  D +++ +WLPVD YVGG
Sbjct  473  WLEVTRE-DGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGG  531

Query  552  IEHAILHLLYARFFTKALHDRNLIGFKEPFNRLLTQGMVQGLTYRNAKNGSYISPELVSD  611
             EHA+LHLLYARF  K L D  ++  KEPF++L+ QGM+ G +YR+++ +   +  +   
Sbjct  532  AEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKR  591

Query  612  DSDPRDPESGDRLEVLFEKMSKSKYNGVDPAVVIDRYGADTARMFILFKAPPEKDLEWDD  671
            D+   + E+G+ LE    KMSKS  N V+P  V+++YGADT R++ +F +P +  + W +
Sbjct  592  DGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSE  651

Query  672  ADVEGQFRFLQRLIRLIDSFAWPKTDGENASISSANLIIDSADLSEEEIN-MRRATHKAI  730
             ++EG  +FL+R+ RL                      I + +++EE+   + +  + ++
Sbjct  652  EGLEGSRKFLDRVYRL----------------------ITTKEITEENSGALDKVYNETV  689

Query  731  EAITEDLSGDIQLNTAISELMKLSNSLSGKLDKVRNEVAAEALSVLVRLMAPFAPHLAEE  790
             A+TE++ +++++NTAI++LM + N+ + K DK+ ++ A      +V+L+APFAPHL+EE
Sbjct  690  KAVTEQV-DQMKFNTAIAQLMVFVNA-ANKEDKLFSDYAKG----FVQLIAPFAPHLGEE  743

Query  791  FWLKLHGHG-SIHQQSWPVIDPSALVLETIELVIQVKGKVRGKIQVPANADKKTLEELAL  849
            +W  L + G SI   +WP  D S LV + +E+V+Q+KGKV++K+ V+ +  +  L+E+AL
Sbjct  744  LWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVAL  803

Query  850  NSDIAVKWLEGQSPRRIIIVPGKLVNLV  877
             ++     + G+   ++I VP KLVN+V
Sbjct  804  ANEKVQAEIAGKDIIKVIAVPNKLVNIV  831

841) leuS in NC_014448


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  567 bits (2142),  Expect = 9e-163, Method: Compositional matrix adjust.
 Identities = 381/843 (46%), Positives = 553/843 (66%), Gaps = 69/843 (8%)

Query  2    YNHLKIEQKWQKYWQQNKTFKT-TNHHLQKFYVLDMFPYPSASGLHIGHPLGYTATDIIA  60
            Y+H  IE KWQ +W +N TFKT T+    KFY LDMFPYPS++GLH+GHP GYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  61   RFKRLNNFDVLHPIGWDAFGLPAEQYALSTKNHPAKFTQENIQNFKKQLISLGFSYDWDK  120
            RFKR +  +VLHP+GWDAFGLPAEQYA+ T N+PA FT ENI NFK+Q+ +LGFSYDWD+
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  121  EVDTTDPLFYEQTQKIFALLYKHNLAEIREVEVNWCPELATvlaneevlvneeGQLVSER  180
            EV+TTDP +Y  TQ IF+ LY   LA   EV VNW  EL+T         +   +  SER
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGT----AIANEEVLPDGTSER  179

Query  181  GGFLVYPKKMKQWVLKITQYADRLLEDLKLVNFPSSLKSLQENWIGKSLGWNVKFKLQDK  240
            GG+ V  K M+QW+LKIT YA+RLLEDL  V+ P S+K +Q NWIGKS G NV FK++D 
Sbjct  180  GGYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDT  239

Query  241  QKDVDIFTTRLDTIFGATFLAISPNHWLAEEL--ANQNPAIKTFIENFAARE----KQKN  294
            +KD  +FTTR DT+FGAT+  ++P+H L + +  ++Q  A+  +  + + +      +  
Sbjct  240  DKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA  299

Query  295  NSKTGIATNLFAINPVNNKEIPIFICDYVIANYQTGALMGVPSHDERDKEFALLNNIEFI  354
            + KTG+ T  +AINPVN KE+P+ I DYV+A+Y TGA+M+VP+HDERD EFA   N+++I
Sbjct  300  KEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDII  359

Query  355  EVINE---------KEKLINSKKY-NNLTIFQARAHIHFDLKNEGKSNQVKAFKIKDWVF  404
             V++           + L  +  + + L    A A +   L  EG +N+  +++++DW+F
Sbjct  360  PVLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLF  419

Query  405  SRQRYWGEPFP-IYFDEDGKIYLEEKLVE--LPYMENITPSGDGQSPLANNKSWVFFEKE  461
            SRQRYWGEP+P I  +++    + E  +   LP   +I PSG G+SPLAN   W+   +E
Sbjct  420  SRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRE  479

Query  462  -GKKYRRETNTMPQWAGSSWYFLAYILKNADGSYLDIESKEAYQRFEKWMPVDLYIGGQE  520
             G K RRETNTMPQWAGSSWY+L YI  +      D E       + +W+PVD+Y+GG E
Sbjct  480  DGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEEL------LKQWLPVDIYVGGAE  533

Query  521  HAVGHLIYSRFWYKFLYDLKIVPTKEPFYKVVNQGMLLGTD-------------------  561
            HAV HL+Y+RFW K LYDL +VPTKEPF K+ NQGM+LGT                    
Sbjct  534  HAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDG  593

Query  562  --------------GQKMSKSKGNIINPNEVVNQFGADSLRIYLMFMSPLIDTKAWSVEG  607
                            KMSKS  N++NP++VV+Q+GAD+LR+Y MFM+PL  + AWS EG
Sbjct  594  SFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEG  653

Query  608  IQGIKKWVDRIVRIMQKSFIYEENYSNAEFESIYHQSIKEIGENIEALKYNIAISKMMVY  667
            ++G +K +DR+ R++    I EEN  ++ ++ +Y++++K + E+++ +K+N AI+++MV+
Sbjct  654  LEGSRKFLDRVYRLITTKEITEEN--SGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVF  711

Query  668  INHLYKQEILSSKKYLVDFLIMFSTFAPHIAEELLEQLEQK--PIHLQQWPTFDQSKILS  725
            +N   K++ L S  Y  +F+ +++ FAPH++EEL + L     +I    WP++D+SK++ 
Sbjct  712  VNAANKEDKLFS-DYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVE  770

Query  726  NIVNIAVQVNGKLRAIIQKNDEDSKEDILNKAKSNENVLKYIQNKDIVKEIYIKDKIVTL  785
            N V+I VQ++GK++A +    + S+E++ + A +NE+V   I  KDI+K I + +K+V +
Sbjct  771  NDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNI  830

Query  786  VVK  788
            V+K
Sbjct  831  VIK  833

842) Desor_5039 in NC_016584


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  567 bits (2142),  Expect = 9e-163, Method: Compositional matrix adjust.
 Identities = 371/867 (43%), Positives = 563/867 (65%), Gaps = 77/867 (8%)

Query  5    YSFPKIESKWQKEWLDNKAYKTEENSSKPKYYALAMFPYPSG-DLHMGHVRNYSIADVIA  63
            Y    IE+KWQ  W DN ++KT  ++SKPK+YAL MFPYPSG +LH+GH   Y+ +D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYKRMTGHNVLHPIGWDSFGLPAENAAIKHQTPPADWTWKNIANMRRQLQEMGISYDWDR  123
            R+KR  GHNVLHP+GWD+FGLPAE+ A+     PA+ T  NIAN +RQ++ +G+SYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVATCHPSYYKWTQWLFLEFYKHGLVYKKKAAVNWCPSCATVLANEQVV-DGGCERCDTL  182
            EV T +P+YYKWTQW+F  +Y  GL Y    +VNW    +T +ANE+V+ DG  ER +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VTKKSLEQWFFRITDYADVLLEDLDKLPGWPEKVKTMQRNWIGRSEGVEVNFALEERPEK  242
            V +K++ QW ++IT YA+ LLEDL+ + +WPE +K MQRNWIG+S G +V F + +    
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  ILVYTTRIDTVFGVSYVVLAPEHPLVLKLVKGTGYEADVLAFIEKMNGLNEIARTSTDAE  302
            + V+TTR DT+FG +Y VLAPEH+LV   +  ++    V  +  + +  +++ART    E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALV-DAITTSDQAEAVADYKRQASLKSDLARTDLAKE  301

Query  303  KEGMFIGAYCLNPLSGKEVPIWIANYVLLEYGTGAVMGVPAHDERDFEFAAKYGLEIKTV  362
            K G+  G+Y +NP++GKE+P+WIA+YVL  YGTGA+M+VPAHDERD EFA ++ L+I  V
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  363  ILPEGSSPEEKELPLKAAYTEEGFMVNSGAFDGLSSQEALERMADEAERMGMGQRKVNFR  422
            +  EG++ EE      AA+TE+G+ +NS+ +DGL    A+ +M +  E  G+G+ +V +R
Sbjct  362  L--EGGNVEE------AAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYR  413

Query  423  LRDWLISRQRYWGAPIPMVYCDSCGTvpvpeeqlpvllppdvvFK---SGENPLATSSSF  479
            LRDWL+SRQRYWG PIP++  +   + +VPE +LP++LP    ++   +GE+PLA  +  
Sbjct  414  LRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDW  473

Query  480  IETTCPKCGGAARRETDTMDTFACSSWYFLRYTDPQNTQEAFSKENVNYWMNVDQYVGGV  539
            +E T    G  +RRET+TM   A SSWY+LRY DP+NT+     E ++ W+ VD YVGG 
Sbjct  474  LEVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGA  532

Query  540  EHAILHLLYARFFTKALKDFGYLDAEEPFQNLLTQGMV----------------------  577
            EHA+LHLLYARF  K L D+G + + EPFQ+L+ QGM+                      
Sbjct  533  EHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRD  592

Query  578  ------------CMNGSKMSKSKGNVVSPGAIIGKYGADTARLFILFAAPPERDLEWSDQ  625
                            +KMSKS  NVV+P+ ++ +YGADT R++ +F +P +  + WS++
Sbjct  593  GSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEE  652

Query  626  GVEGCYRFLNRVWRLVAQFEPllkadpssskassdRWVKLDAEGKEMRRHTHSAIQKVTI  685
            G+EG  +FL+RV RL++  E                    + ++  + +  + +++ VT 
Sbjct  653  GLEGSRKFLDRVYRLITTKEIT------------------EENSGALDKVYNETVKAVTE  694

Query  686  DIGKRYNFNTAISTIMEWVNALYLYKERPNADPEVGREALEGILTLLAPIAPHITEELWR  745
            ++++  +FNTAI+ +M       ++ + +N +  +  +   G++ L+AP+APH+ EELW+
Sbjct  695  QVDQM-KFNTAIAQLM-------VFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  746  EL-GHTDSIHLQPWPSVDEAALVQDEVTIILQVNGKVRDRIQAAADISADELEKLALAQP  804
             L +  +SI   PWPS DE+ LV+++V I++Q++GKV+ ++  A D+S +EL+ +ALA+ 
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  805  KVEEFTQGKTVVKVITVPGKLVNIVVK  831
            KV+    GK ++KVI+VP KLVNIV+K
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVIK  833

843) MOS_262 in NC_019552


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  566 bits (2137),  Expect = 2e-162, Method: Compositional matrix adjust.
 Identities = 380/843 (46%), Positives = 552/843 (66%), Gaps = 69/843 (8%)

Query  2    YNHLKIEQKWQKYWQQNKTFKT-TNHHLQKFYVLDMFPYPSASGLHIGHPLGYTATDIIA  60
            Y+H  IE KWQ +W +N TFKT T+    KFY LDMFPYPS++GLH+GHP GYTATDI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  61   RFKRLNNFDVLHPIGWDAFGLPAEQYALSTKNHPAKFTQENIQNFKKQLISLGFSYDWDK  120
            RFKR +  +VLHP+GWDAFGLPAEQYA+ T N+PA FT ENI NFK+Q+ +LGFSYDWD+
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  121  EVDTTDPLFYEQTQKIFALLYKHNLAEIREVEVNWCPELATvlaneevlvneeGQLVSER  180
            EV+TTDP +Y  TQ IF+ LY   LA   EV VNW  EL+T         +   +  SER
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGT----AIANEEVLPDGTSER  179

Query  181  GGFLVYPKKMKQWVLKITQYADRLLEDLKLVNFPSSLKSLQENWIGKSLGWNVKFKLQDK  240
            GG+ V  K M+QW+LKIT YA+RLLEDL  V+ P S+K +Q NWIGKS G NV FK++D 
Sbjct  180  GGYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDT  239

Query  241  QKDVDIFTTRLDTIFGATFLAISPNHWLAEEL--ANQNPAIKTFIENFAARE----KQKN  294
            +KD  +FTTR DT+FGAT+  ++P+H L + +  ++Q  A+  +  + + +      +  
Sbjct  240  DKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA  299

Query  295  NSKTGIATNLFAINPVNNKEIPIFICDYVIANYQTGALMGVPSHDERDKEFALLNNIEFI  354
            + KTG+ T  +AINPVN KE+P+ I DYV+A+Y TGA+M+VP+HDERD EFA   N+++I
Sbjct  300  KEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDII  359

Query  355  EVINE---------KEKLINSKKY-NNLTIFQARAHIHFDLKNEGKSSQVKAFKIKDWVF  404
             V++           + L  +  + + L    A A +   L  EG +++  +++++DW+F
Sbjct  360  PVLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLF  419

Query  405  SRQRYWGEPFP-IYFDEDGKIYLEEKLVE--LPYMENITPSGDGQSPLANNKSWVFFEKE  461
            SRQRYWGEP+P I  +++    + E  +   LP   +I PSG G+SPLAN   W+   +E
Sbjct  420  SRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRE  479

Query  462  -GKKYRRETNTMPQWAGSSWYFLAYILKNADGSYLDIESKEAYQRFEKWMPVDLYIGGQE  520
             G K RRETNTMPQWAGSSWY+L YI  +      D E       + +W+PVD+Y+GG E
Sbjct  480  DGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEEL------LKQWLPVDIYVGGAE  533

Query  521  HAVGHLIYSRFWYKFLYDLKIVPTKEPFYKVVNQGMLLGTD-------------------  561
            HAV HL+Y+RFW K LYDL +VPTKEPF K+ NQGM+LGT                    
Sbjct  534  HAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDG  593

Query  562  --------------GQKMSKSKGNIINPNEVVNQFGADSLRIYLMFMSPLIDTKAWSVEG  607
                            KMSKS  N++NP++VV+Q+GAD+LR+Y MFM+PL  + AWS EG
Sbjct  594  SFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEG  653

Query  608  IQGIKKWVDRIVRIMQKSFIYEENYSNAEFESIYHQSIKEIGENIEALKYNIAISKMMVY  667
            ++G +K +DR+ R++    I EEN  ++ ++ +Y++++K + E+++ +K+N AI+++MV+
Sbjct  654  LEGSRKFLDRVYRLITTKEITEEN--SGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVF  711

Query  668  INHLYKQKILSSKKYLVDFLIMFSTFAPHIAEELLEQLEQK--PIHLQQWPTFDQSKILS  725
            +N   K+  L S  Y  +F+ +++ FAPH++EEL + L     +I    WP++D+SK++ 
Sbjct  712  VNAANKEDKLFS-DYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVE  770

Query  726  NIVNIAVQVNGKLRAIIQKNDEDSKEDILNKAKSNENVLKYIQNKDIVKEIYIKDKIVTL  785
            N V+I VQ++GK++A +    + S+E++ + A +NE+V   I  KDI+K I + +K+V +
Sbjct  771  NDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNI  830

Query  786  VVK  788
            V+K
Sbjct  831  VIK  833

844) Halha_1913 in NC_019978


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  566 bits (2137),  Expect = 2e-162, Method: Compositional matrix adjust.
 Identities = 356/816 (44%), Positives = 531/816 (66%), Gaps = 69/816 (8%)

Query  5    YNFSKVEKKWQQHWEEEGTYQTEINQNQDEYYVLEMFPYPSG-NLHMGHVRNYSLGDVFA  63
            Y+ + +E KWQ  W ++ T++T  + ++  +Y L+MFPYPSG  LH+GH   Y+  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RFRRMQGYNVLHPMGWDAFGLPAENAAIKRDIHPADWTEDNISNMKKQFKMLGLSYDWKR  123
            RF+R QG NVLHPMGWDAFGLPAE+ A+  + +PA+ T +NI+N K+Q++ LG+SYDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVATCKPDYYKWTQWLFLELYKEGLAYKKKAQVNWCPDCQTVLANEQVI-DGECERCDSE  182
            EV T  P+YYKWTQW+F  LY  GLAY     VNW  +  T +ANE+V+ DG  ER +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VIDDKELEQWFFKITdyadqlladhdlldGWPERVKTMQQNWIGRSEGAKIKFKIKESNH  242
            V+  K + QW +KIT    + L ++    +WPE +K MQ+NWIG+S GA++ FK+K+++ 
Sbjct  184  VV-RKPMRQWMLKIT-AYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDK  241

Query  243  ELEVFTTRPDTIYGATYMVLAPEHPLVDELITGKENETKIRDFIAEVKDQDEEERTGTDA  302
            ++ VFTTRPDT++GATY VLAPEH+LVD + T+ + E+ + D+  +   + +  RT+   
Sbjct  242  DFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEA-VADYKRQASLKSDLARTDLAK  300

Query  303  KKLGIDTGIKAINPVTKEEIPVMIANYVLMDYGTGAIMAVPAHDERDFEFAKEYDLPIRV  362
             K G+ TG  AINPV   E+PV IA+YVL  YGTGAIMAVPAHDERD EFAK+++L I  
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  363  VIQPDDEELTADKLEEAYTEDGLVTNSKMLNGLSIDDAFDKIVDYLEEEGIGNKDVNYRL  422
            V++ ++ E      E A+TEDGL  NS  L+GL    A+ K+V+ LE EG+GN +V YRL
Sbjct  361  VLEGGNVE------EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRL  414

Query  423  RDWLISRQRYWGTPIPVIHCNNCGTVPVPEEDLPVKLPTNVEF--TGEGQSPLANVDEFV  480
            RDWL+SRQRYWG PIP+IH ++  + +VPE +LP+ LP   ++  +G G+SPLANV + +
Sbjct  415  RDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWL  474

Query  481  QTTCPECGQAAKREVDTMDTFVDSSWYYLRYTSPELTTKVFDQERANYWMNVDQYIGGIE  540
            + T  + G  ++RE +TM    +SSWYYLRY  P+ T K+ D+E  + W+ VD Y+GG E
Sbjct  475  EVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAE  533

Query  541  HAILHLLYARFFMKFLNDQGLVEAKEPFASLLTQGMVL----------------------  578
            HA+LHLLYARF  K L D G+V +KEPF  L+ QGM+L                      
Sbjct  534  HAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDG  593

Query  579  ------------LDGAKMSKSKGNIVDPLEILDEYGADVARLFILFAAPPERDLDWNDEG  626
                           AKMSKS  N+V+P +++++YGAD  R++ +F +P +  + W++EG
Sbjct  594  SFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEG  653

Query  627  VEGAQRFLNRVWRLVAKNIDQIKEVTTEFEINHDLDKKLHRQLHVAIRDITSDIEERGQL  686
            +EG+++FL+RV RL++ +           EI ++    L++  + +++ +T ++++  ++
Sbjct  654  LEGSRKFLDRVYRLITTK-----------EITEENSGALDKVYNETVKAVTEQVDQM-KF  701

Query  687  NTAISSIMELVNAVYKYLNEAKQINSQLLKVVVEDIVLLLAPFAPHMTEELWTKL-GYED  745
            NTAI+ +M +VNA  K        + +L+     ++V L+APFAPH+ EELW  L +  +
Sbjct  702  NTAIAQLMVFVNAANK--------EDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGE  753

Query  746  SIHNQEWPNFDQEATKKDEIEIVVQVNGKVRDKVKV  781
            SI    WP++D+     +++EIVVQ++GKV+ K+ V
Sbjct  754  SISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVV  789

845) Sbal175_1096 in NC_017571


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  566 bits (2138),  Expect = 2e-162, Method: Compositional matrix adjust.
 Identities = 366/868 (43%), Positives = 571/868 (66%), Gaps = 51/868 (5%)

Query  20   YNPSEIEALVQKHWHDNKTFEVTEDANKEKFYCLSMFPYPSGR-LHMGHVRNYTIGDVVA  78
            Y+ + IE+  Q  W DN TF    DA+K KFY L MFPYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  79   RFQRLQGKNVLQPIGWDSFGLPAENAAINNKTAPAPWTYENIEYMKNQLKLLGFGYDWSR  138
            RF+R QG NVL+P+GWD+FGLPAE+ A++    PA  T ENI   K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  139  EIATCTPEYYRWEQWFFTKLYEKGLVYKKTASVNWCPNDETVLANEQV-QDGCCWRCDTP  197
            E+ T  P+YY+W QW+FTKLYEKGL Y    +VNW  +  T +ANE+V  DG   R + P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  198  VEQKEIPQWFIKITAYAEELLNDIDTLDGWPDQVKTMQRNWIGRSEGVEMTFGVAGHDKS  257
            V +K + QW +KITAYAE LL+D++ +D WP+ +K MQRNWIG+S G ++TF V + DK 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  258  FDIYTTRPDTLMGVTYVAIAAGHPLAEIAAHTNPELAAFIDECKNSTTSEAELA----TM  313
            F ++TTRPDTL G TY  +A+ H+L  + A T ++ A  + + K  ++  ++LA    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHAL--VDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  314  EKRGVATGLFAIHPITGKQVPIWAANFVLMNYGTGAVMSVPGHDQRDFEFAKKYGLAIEA  373
            EK GV TG +AI+P+ GK++P+W A++VL +YGTGA+M+VP+HD+RD EFAK++ L I +
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  374  VIKPVDGDVDISEAAYTEKGVLFNSGEFDGLDFEAGFNAIANKLVAEGKGKRQVNYRLRD  433
            V+     + ++ EAA+TE G+ +NS+ +DGLD  +++  + + L AEG G+ +V YRLRD
Sbjct  361  VL----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  434  WGVSRQRYWGAPIPMVTLADGTVIPTPADQLPVLLP--EDVVMDGI-QSPIKADKEWAK-  489
            W  SRQRYWG PIP++   DGT  + P  +LP++LP   D+   G  +SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  490  TQVNGQDALRETDTFDTFMESSWYYARYCSPHADEML-DPAKANYWLPVDQYIGGIEHAC  548
            T+ +G  + RET+T      SSWYY RY  PH  E L D    + WLPVD Y+GG EHA 
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  549  MHLLYFRFFHKLLRDAGLVNSNEPAKQLLTQGMVLADAFYYINEKGARVWVSPLDVATTE  608
            +HLLY RF HK+L D G+V ++EP ++L+ QGM+L+ +  Y + +GA        + +T+
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS--YRDSRGA--------LVATD  586

Query  609  KDDKGRITKAIDKDGNELVYTGMSKMSKSKNNGIDPQVMVEKYGADTVRLFMMFASPPEL  668
            K +K R    ++ +  E +  + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P + 
Sbjct  587  KVEK-RDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  669  TLEWQESGVEGAHRFIKRLWKL-ANEHVNQDNSEALDVSTLTSDQKALRREVHKTIAKVT  727
            ++ W E G+EG+++F+ R+ +L +  ++ ++NS ALD            +  + T+  VT
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALD------------KVYNETVKAVT  693

Query  728  DDIGRRQMFNTAVAAVMELMNHLQKAPQTTGQDNAIIGEALSAIVRLLYPIIPHVSFNLW  787
            +++++ + FNTA+A +M ++N       ++ +++ ++++   ++V+L+ P+ PH++ +LW
Sbjct  694  EQVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELW  745

Query  788  NEL-GNASNIEDSQWPVVDEAALVEDSKLIVVQVNGKVRAKITVAADADKESVEALGMSD  846
            + L +++ +I    WP  DE+ LVE+   IVVQ++GKV+AK+ VA D  +E ++ +++++
Sbjct  746  QALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALAN  805

Query  847  EHVIKYLDGLTVRKVIYVPGKLLSIVAN  874
            E V   + G  + KVI VP KL++IV +
Sbjct  806  EKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

846) Sbal117_3406 in NC_017579


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  566 bits (2138),  Expect = 2e-162, Method: Compositional matrix adjust.
 Identities = 366/868 (43%), Positives = 571/868 (66%), Gaps = 51/868 (5%)

Query  20   YNPSEIEALVQKHWHDNKTFEVTEDANKEKFYCLSMFPYPSGR-LHMGHVRNYTIGDVVA  78
            Y+ + IE+  Q  W DN TF    DA+K KFY L MFPYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  79   RFQRLQGKNVLQPIGWDSFGLPAENAAINNKTAPAPWTYENIEYMKNQLKLLGFGYDWSR  138
            RF+R QG NVL+P+GWD+FGLPAE+ A++    PA  T ENI   K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  139  EIATCTPEYYRWEQWFFTKLYEKGLVYKKTASVNWCPNDETVLANEQV-QDGCCWRCDTP  197
            E+ T  P+YY+W QW+FTKLYEKGL Y    +VNW  +  T +ANE+V  DG   R + P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  198  VEQKEIPQWFIKITAYAEELLNDIDTLDGWPDQVKTMQRNWIGRSEGVEMTFGVAGHDKS  257
            V +K + QW +KITAYAE LL+D++ +D WP+ +K MQRNWIG+S G ++TF V + DK 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  258  FDIYTTRPDTLMGVTYVAIAAGHPLAEIAAHTNPELAAFIDECKNSTTSEAELA----TM  313
            F ++TTRPDTL G TY  +A+ H+L  + A T ++ A  + + K  ++  ++LA    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHAL--VDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  314  EKRGVATGLFAIHPITGKQVPIWAANFVLMNYGTGAVMSVPGHDQRDFEFAKKYGLAIEA  373
            EK GV TG +AI+P+ GK++P+W A++VL +YGTGA+M+VP+HD+RD EFAK++ L I +
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  374  VIKPVDGDVDISEAAYTEKGVLFNSGEFDGLDFEAGFNAIANKLVAEGKGKRQVNYRLRD  433
            V+     + ++ EAA+TE G+ +NS+ +DGLD  +++  + + L AEG G+ +V YRLRD
Sbjct  361  VL----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  434  WGVSRQRYWGAPIPMVTLADGTVIPTPADQLPVLLP--EDVVMDGI-QSPIKADKEWAK-  489
            W  SRQRYWG PIP++   DGT  + P  +LP++LP   D+   G  +SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  490  TQVNGQDALRETDTFDTFMESSWYYARYCSPHADEML-DPAKANYWLPVDQYIGGIEHAC  548
            T+ +G  + RET+T      SSWYY RY  PH  E L D    + WLPVD Y+GG EHA 
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  549  MHLLYFRFFHKLLRDAGLVNSNEPAKQLLTQGMVLADAFYYINEKGARVWVSPLDVATTE  608
            +HLLY RF HK+L D G+V ++EP ++L+ QGM+L+ +  Y + +GA        + +T+
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS--YRDSRGA--------LVATD  586

Query  609  KDDKGRITKAIDKDGNELVYTGMSKMSKSKNNGIDPQVMVEKYGADTVRLFMMFASPPEL  668
            K +K R    ++ +  E +  + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P + 
Sbjct  587  KVEK-RDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  669  TLEWQESGVEGAHRFIKRLWKL-ANEHVNQDNSEALDVSTLTSDQKALRREVHKTIAKVT  727
            ++ W E G+EG+++F+ R+ +L +  ++ ++NS ALD            +  + T+  VT
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALD------------KVYNETVKAVT  693

Query  728  DDIGRRQMFNTAVAAVMELMNHLQKAPQTTGQDNAIIGEALSAIVRLLYPIIPHVSFNLW  787
            +++++ + FNTA+A +M ++N       ++ +++ ++++   ++V+L+ P+ PH++ +LW
Sbjct  694  EQVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELW  745

Query  788  NEL-GNASNIEDSQWPVVDEAALVEDSKLIVVQVNGKVRAKITVAADADKESVEALGMSD  846
            + L +++ +I    WP  DE+ LVE+   IVVQ++GKV+AK+ VA D  +E ++ +++++
Sbjct  746  QALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALAN  805

Query  847  EHVIKYLDGLTVRKVIYVPGKLLSIVAN  874
            E V   + G  + KVI VP KL++IV +
Sbjct  806  EKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

847) leuS in NC_009052


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  566 bits (2138),  Expect = 2e-162, Method: Compositional matrix adjust.
 Identities = 366/868 (43%), Positives = 571/868 (66%), Gaps = 51/868 (5%)

Query  20   YNPSEIEALVQKHWHDNKTFEVTEDANKEKFYCLSMFPYPSGR-LHMGHVRNYTIGDVVA  78
            Y+ + IE+  Q  W DN TF    DA+K KFY L MFPYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  79   RFQRLQGKNVLQPIGWDSFGLPAENAAINNKTAPAPWTYENIEYMKNQLKLLGFGYDWSR  138
            RF+R QG NVL+P+GWD+FGLPAE+ A++    PA  T ENI   K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  139  EIATCTPEYYRWEQWFFTKLYEKGLVYKKTASVNWCPNDETVLANEQV-QDGCCWRCDTP  197
            E+ T  P+YY+W QW+FTKLYEKGL Y    +VNW  +  T +ANE+V  DG   R + P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  198  VEQKEIPQWFIKITAYAEELLNDIDTLDGWPDQVKTMQRNWIGRSEGVEMTFGVAGHDKS  257
            V +K + QW +KITAYAE LL+D++ +D WP+ +K MQRNWIG+S G ++TF V + DK 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  258  FDIYTTRPDTLMGVTYVAIAAGHPLAEIAAHTNPELAAFIDECKNSTTSEAELA----TM  313
            F ++TTRPDTL G TY  +A+ H+L  + A T ++ A  + + K  ++  ++LA    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHAL--VDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  314  EKRGVATGLFAIHPITGKQVPIWAANFVLMNYGTGAVMSVPGHDQRDFEFAKKYGLAIEA  373
            EK GV TG +AI+P+ GK++P+W A++VL +YGTGA+M+VP+HD+RD EFAK++ L I +
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  374  VIKPVDGDVDISEAAYTEKGVLFNSGEFDGLDFEAGFNAIANKLVAEGKGKRQVNYRLRD  433
            V+     + ++ EAA+TE G+ +NS+ +DGLD  +++  + + L AEG G+ +V YRLRD
Sbjct  361  VL----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  434  WGVSRQRYWGAPIPMVTLADGTVIPTPADQLPVLLP--EDVVMDGI-QSPIKADKEWAK-  489
            W  SRQRYWG PIP++   DGT  + P  +LP++LP   D+   G  +SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  490  TQVNGQDALRETDTFDTFMESSWYYARYCSPHADEML-DPAKANYWLPVDQYIGGIEHAC  548
            T+ +G  + RET+T      SSWYY RY  PH  E L D    + WLPVD Y+GG EHA 
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  549  MHLLYFRFFHKLLRDAGLVNSNEPAKQLLTQGMVLADAFYYINEKGARVWVSPLDVATTE  608
            +HLLY RF HK+L D G+V ++EP ++L+ QGM+L+ +  Y + +GA        + +T+
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS--YRDSRGA--------LVATD  586

Query  609  KDDKGRITKAIDKDGNELVYTGMSKMSKSKNNGIDPQVMVEKYGADTVRLFMMFASPPEL  668
            K +K R    ++ +  E +  + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P + 
Sbjct  587  KVEK-RDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  669  TLEWQESGVEGAHRFIKRLWKL-ANEHVNQDNSEALDVSTLTSDQKALRREVHKTIAKVT  727
            ++ W E G+EG+++F+ R+ +L +  ++ ++NS ALD            +  + T+  VT
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALD------------KVYNETVKAVT  693

Query  728  DDIGRRQMFNTAVAAVMELMNHLQKAPQTTGQDNAIIGEALSAIVRLLYPIIPHVSFNLW  787
            +++++ + FNTA+A +M ++N       ++ +++ ++++   ++V+L+ P+ PH++ +LW
Sbjct  694  EQVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELW  745

Query  788  NEL-GNASNIEDSQWPVVDEAALVEDSKLIVVQVNGKVRAKITVAADADKESVEALGMSD  846
            + L +++ +I    WP  DE+ LVE+   IVVQ++GKV+AK+ VA D  +E ++ +++++
Sbjct  746  QALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALAN  805

Query  847  EHVIKYLDGLTVRKVIYVPGKLLSIVAN  874
            E V   + G  + KVI VP KL++IV +
Sbjct  806  EKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

848) leuS in NC_009997


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  566 bits (2137),  Expect = 2e-162, Method: Compositional matrix adjust.
 Identities = 366/868 (43%), Positives = 571/868 (66%), Gaps = 51/868 (5%)

Query  20   YNPSEIEALVQKHWHDNKTFEVTEDANKEKFYCLSMFPYPSGR-LHMGHVRNYTIGDVVA  78
            Y+ + IE+  Q  W DN TF    DA+K KFY L MFPYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  79   RFQRLQGKNVLQPIGWDSFGLPAENAAINNKTAPAPWTYENIEYMKNQLKLLGFGYDWSR  138
            RF+R QG NVL+P+GWD+FGLPAE+ A++    PA  T ENI   K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  139  EIATCTPEYYRWEQWFFTKLYEKGLVYKKTASVNWCPNDETVLANEQV-QDGCCWRCDTP  197
            E+ T  P+YY+W QW+FTKLYEKGL Y    +VNW  +  T +ANE+V  DG   R + P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  198  VEQKEIPQWFIKITAYAEELLNDIDTLDGWPDQVKTMQRNWIGRSEGVEMTFGVAGHDKS  257
            V +K + QW +KITAYAE LL+D++ +D WP+ +K MQRNWIG+S G ++TF V + DK 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  258  FDIYTTRPDTLMGVTYVAIAAGHPLAEIAAQTNPELAAFIDECKNSTTSEAELA----TM  313
            F ++TTRPDTL G TY  +A+ H+L  + A T ++ A  + + K  ++  ++LA    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHAL--VDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  314  EKRGVATGLFAIHPITGKQVPIWAANFVLMNYGTGAVMSVPGHDQRDFEFAKKYGLAIEA  373
            EK GV TG +AI+P+ GK++P+W A++VL +YGTGA+M+VP+HD+RD EFAK++ L I +
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  374  VIKPVDGDVDISEAAYTEKGVLFNSGEFDGLDFEAGFNAIANKLVAEGKGKRQVNYRLRD  433
            V+     + ++ EAA+TE G+ +NS+ +DGLD  +++  + + L AEG G+ +V YRLRD
Sbjct  361  VL----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  434  WGVSRQRYWGAPIPMVTLADGTVIPTPADQLPVLLP--EDVVMDGI-QSPIKADKEWAK-  489
            W  SRQRYWG PIP++   DGT  + P  +LP++LP   D+   G  +SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  490  TQVNGQDALRETDTFDTFMESSWYYARYCSPHADEML-DPAKANYWLPVDQYIGGIEHAC  548
            T+ +G  + RET+T      SSWYY RY  PH  E L D    + WLPVD Y+GG EHA 
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  549  MHLLYFRFFHKLLRDAGLVNSNEPAKQLLTQGMVLADAFYYINEKGARVWVSPLDVATTE  608
            +HLLY RF HK+L D G+V ++EP ++L+ QGM+L+ +  Y + +GA        + +T+
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS--YRDSRGA--------LVATD  586

Query  609  KDDKGRITKAIDKDGNELVYTGMSKMSKSKNNGIDPQVMVEKYGADTVRLFMMFASPPEL  668
            K +K R    ++ +  E +  + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P + 
Sbjct  587  KVEK-RDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  669  TLEWQESGVEGAHRFIKRLWKL-ANEHVNQDNSEALDASKLTSDQKALRREVHKTIAKVT  727
            ++ W E G+EG+++F+ R+ +L +  ++ ++NS ALD            +  + T+  VT
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALD------------KVYNETVKAVT  693

Query  728  DDIGRRQMFNTAVAAVMELMNHLQKAPQTTGQDNAIIGEALSAIVRLLYPIIPHVSFNLW  787
            +++++ + FNTA+A +M ++N       ++ +++ ++++   ++V+L+ P+ PH++ +LW
Sbjct  694  EQVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELW  745

Query  788  NEL-GNASNIEDSQWPVVDEAALVEDSKLIVVQVNGKVRAKITVAADADKESVEALGMSD  846
            + L +++ +I    WP  DE+ LVE+   IVVQ++GKV+AK+ VA D  +E ++ +++++
Sbjct  746  QALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALAN  805

Query  847  EHVIKYLDGLTVRKVIYVPGKLLSIVAN  874
            E V   + G  + KVI VP KL++IV +
Sbjct  806  EKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

849) Sbal678_3462 in NC_016901


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  566 bits (2137),  Expect = 2e-162, Method: Compositional matrix adjust.
 Identities = 366/868 (43%), Positives = 571/868 (66%), Gaps = 51/868 (5%)

Query  5    YNPSEIEALVQKHWHDNKTFEVTEDANKEKFYCLSMFPYPSGR-LHMGHVRNYTIGDVVA  63
            Y+ + IE+  Q  W DN TF    DA+K KFY L MFPYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RFQRLQGKNVLQPIGWDSFGLPAENAAINNKTAPAPWTYENIEYMKNQLKLLGFGYDWSR  123
            RF+R QG NVL+P+GWD+FGLPAE+ A++    PA  T ENI   K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EIATCTPEYYRWEQWFFTKLYEKGLVYKKTASVNWCPNDETVLANEQV-QDGCCWRCDTP  182
            E+ T  P+YY+W QW+FTKLYEKGL Y    +VNW  +  T +ANE+V  DG   R + P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VEQKEIPQWFIKITAYAEELLNDIDTLDGWPDQVKTMQRNWIGRSEGVEMTFGVAGHDKS  242
            V +K + QW +KITAYAE LL+D++ +D WP+ +K MQRNWIG+S G ++TF V + DK 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  FDIYTTRPDTLMGVTYVAIAAGHPLAEIAAQTNPELAAFIDECKNSTTSEAELA----TM  298
            F ++TTRPDTL G TY  +A+ H+L  + A T ++ A  + + K  ++  ++LA    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHAL--VDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  299  EKRGVATGLFAIHPITGKQVPIWAANFVLMNYGTGAVMSVPGHDQRDFEFAKKYGLAIEA  358
            EK GV TG +AI+P+ GK++P+W A++VL +YGTGA+M+VP+HD+RD EFAK++ L I +
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VIKPVDGDVDISEAAYTEKGVLFNSGEFDGLDFEAGFNAIANKLVAEGKGKRQVNYRLRD  418
            V+     + ++ EAA+TE G+ +NS+ +DGLD  +++  + + L AEG G+ +V YRLRD
Sbjct  361  VL----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  419  WGVSRQRYWGAPIPMVTLADGTVIPTPADQLPVLLP--EDVVMDGI-QSPIKADKEWAK-  474
            W  SRQRYWG PIP++   DGT  + P  +LP++LP   D+   G  +SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  475  TQVNGQDALRETDTFDTFMESSWYYARYCSPHADEML-DPAKANYWLPVDQYIGGIEHAC  533
            T+ +G  + RET+T      SSWYY RY  PH  E L D    + WLPVD Y+GG EHA 
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  534  MHLLYFRFFHKLLRDAGLVNSNEPAKQLLTQGMVLADAFYYINEKGARVWVSPLDVATTE  593
            +HLLY RF HK+L D G+V ++EP ++L+ QGM+L+ +  Y + +GA        + +T+
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS--YRDSRGA--------LVATD  586

Query  594  KDDKGRITKAIDKDGNELVYTGMSKMSKSKNNGIDPQVMVEKYGADTVRLFMMFASPPEL  653
            K +K R    ++ +  E +  + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P + 
Sbjct  587  KVEK-RDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  654  TLEWQESGVEGAHRFIKRLWKL-ANEHVNQDNSEALDASKLTSDQKALRREVHKTIAKVT  712
            ++ W E G+EG+++F+ R+ +L +  ++ ++NS ALD            +  + T+  VT
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALD------------KVYNETVKAVT  693

Query  713  DDIGRRQMFNTAVAAVMELMNHLQKAPQTTGQDNAIIGEALSAIVRLLYPIIPHVSFNLW  772
            +++++ + FNTA+A +M ++N       ++ +++ ++++   ++V+L+ P+ PH++ +LW
Sbjct  694  EQVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELW  745

Query  773  NEL-GNASNIEDSQWPVVDEAALVEDSKLIVVQVNGKVRAKITVAADADKESVEALGMSD  831
            + L +++ +I    WP  DE+ LVE+   IVVQ++GKV+AK+ VA D  +E ++ +++++
Sbjct  746  QALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALAN  805

Query  832  EHVIKYLDGLTVRKVIYVPGKLLSIVAN  859
            E V   + G  + KVI VP KL++IV +
Sbjct  806  EKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

850) leuS in NC_008321


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  566 bits (2137),  Expect = 2e-162, Method: Compositional matrix adjust.
 Identities = 372/868 (43%), Positives = 572/868 (66%), Gaps = 51/868 (5%)

Query  5    YNPSEIEALVQKHWHDNKTFEVTEDANKEKFYCLSMFPYPSGR-LHMGHVRNYTIGDVVA  63
            Y+ + IE+  Q  W DN TF    DA+K KFY L MFPYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RFQRLQGKNVLQPIGWDSFGLPAENAAINNKTAPAPWTYQNIEYMKNQLKLLGFGYDWSR  123
            RF+R QG NVL+P+GWD+FGLPAE+ A++    PA  T +NI   K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EIATCTPEYYRWEQWFFTKLYEKGLVYKKTASVNWCPNDETVLANEQV-QDGCCWRCDTP  182
            E+ T  P+YY+W QW+FTKLYEKGL Y    +VNW  +  T +ANE+V  DG   R + P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VEQKEIPQWFIKITAYAEELLNDIDTLDGWPEQVKTMQRNWIGRSEGVEMTFGVAGSDKS  242
            V +K + QW +KITAYAE LL+D++ +D WPE +K MQRNWIG+S G ++TF V ++DK 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  FDIYTTRPDTLMGVTYVAIAAGHPLAELAAQTNPELAQFIEECKNSTTSEADLA----TM  298
            F ++TTRPDTL G TY  +A+ H+L +  A T ++ A+ + + K  ++  +DLA    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVD--AITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  299  EKRGVATGLYAIHPITGKQVPIWAANFVLMNYGTGAVMSVPGHDQRDYEFAKKYNLSIEA  358
            EK GV TG YAI+P+ GK++P+W A++VL +YGTGA+M+VP+HD+RD EFAK++NL I +
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VIKPVDGELDISEAAYTEKGVLFNSGEFDGLDFDGAFNAIADKLVAEGKGKRQVNYRLRD  418
            V+       ++ EAA+TE G+ +NS+ +DGLD  +A+  + + L AEG G+ +V YRLRD
Sbjct  361  VLEGG----NVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  419  WGVSRQRYWGAPIPMVTLADGTVIPTPEDQLPVILP--EDVVMDGI-QSPIKADKEWAK-  474
            W  SRQRYWG PIP++   DGT  + PE +LP++LP   D+   G  +SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  475  TQVNGQDALRETDTFDTFMESSWYYARYCSPQADQML-DPTKANYWLPVDQYIGGIEHAC  533
            T+ +G  + RET+T      SSWYY RY  P+  + L D    + WLPVD Y+GG EHA 
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  534  MHLLYFRFFHKLLRDAGLVNSNEPAKQLLTQGMVLADAFYYNNDKGARVWVSPLDVVTTE  593
            +HLLY RF HK+L D G+V ++EP ++L+ QGM+L+ +  Y + +GA        +V+T+
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS--YRDSRGA--------LVATD  586

Query  594  KDDKGRVTKAIDKDGNELVYTGMCKMSKSKNNGIDPQVMVEKYGADTVRLFMMFASPPEL  653
            K +K R    ++ +  E +  +  KMSKS +N ++P+ +VE+YGADT+R++ MF +P + 
Sbjct  587  KVEK-RDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  654  TLEWQESGVEGAHRFIKRLWKL-ASDYVAQDNSEALDVSKLTSEQKALRREVHKTIAKVT  712
            ++ W E G+EG+++F+ R+ +L ++  ++++NS ALD            +  + T+  VT
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALD------------KVYNETVKAVT  693

Query  713  DDIGRRQMFNTAVAAVMELMNHLQKAPQTTGQDRAIIGEALTAVVRLLYPIIPHVSFTLW  772
            +++++ + FNTA+A +M ++N       ++ ++  ++++   + V+L+ P+ PH++  LW
Sbjct  694  EQVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELW  745

Query  773  NEL-GNTNSIEDSQWPVVDESALVEDSKLIVVQVNGKVRAKITVAADADQASVEALGMAD  831
            + L ++ +SI    WP  DES LVE+   IVVQ++GKV+AK+ VA D  +  ++ +++A+
Sbjct  746  QALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALAN  805

Query  832  EQVIKYLDGVTVRKVIYVPGKLLSIVAN  859
            E+V   + G  + KVI VP KL++IV +
Sbjct  806  EKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

851) leuS in NC_009481


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  566 bits (2137),  Expect = 2e-162, Method: Compositional matrix adjust.
 Identities = 366/862 (43%), Positives = 569/862 (67%), Gaps = 39/862 (4%)

Query  20   YDPIALEQRWQSQWQQDDLYATRSPEPGQNAFYALSMFPYPSGS-LHMGHVRNYVITDVI  78
            YD  A+E +WQ+ W +++ + T + ++++  FYAL MFPYPSG+ LH+GH   Y  TD++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKT-GTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDIL  62

Query  79   ARAQRMRGDSVLHPMGWDAFGLPAENAAIERQVDPGVWTDRNIEQMKAQLARLGLSIDWS  138
            +R +R +G++VLHPMGWDAFGLPAE+ A++   DP+  T  NI + K Q+  LG+S DW 
Sbjct  63   SRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWD  122

Query  139  REQATCHADYYRWTQWLFLELMDQGLAYQKDATVNWDPVDQTVLANEQVDSEGRSWRSGA  198
            RE  T +++YY+WTQW+F  L ++GLAY+ +  VNW     T +ANE+V ++G S R+G 
Sbjct  123  REVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGY  182

Query  199  LVEQKNLRQWFLRITNYadallddldllKGWPERVRTMQANWIGRSIGAEIDFRVSDHDD  258
             V +K +RQW L+IT YA+ LL+DL+ + +WPE ++ MQ NWIG+S GA++ F+V D D 
Sbjct  183  PVVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDK  241

Query  259  AVITVFTTRADTLHGVSYVVLAPEHPLVATLTAEHQRESVAAFRDLVGELSADERTADDR  318
              +TVFTTR+DTL G +Y VLAPEH+LV ++T+ +Q E+VA ++   +  S   RT   +
Sbjct  242  D-FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  319  PKRGVPIGATAVNPANGESIPIWIADYVLAGYGTGAVMGVPAHDERDFLFARTYELPVKR  378
             K GV  G+ A+NP NG  +P+WIADYVLA+YGTGA+M+VPAHDERD  FA+ ++L +  
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  379  VIQAAGTSDHLSDGEAWTGPGILLNSGRFDGQSSEEARQEITAHGQELGWARPKRQYRLR  438
            V++++       +  A T  G+ +NS+ +DG     A   +    +  G +  +  YRLR
Sbjct  361  VLEGGNV-----EEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  439  DWLISRQRYWGCPIPVIHCDHCGAVPVPADQLPVTLP--KDVDLQGKGGSPLASLQSWVN  496
            DWL+SRQRYWG PIP+IH ++  + +VP  +LP+ LP  KD+   G G SPLA++  W++
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  497  VKCPSCGRDARRETDTMDTFMCSSWYFLRFADPHNTERAFDADAVERWLPVQQYVGGIEH  556
            V     G  +RRET+TM     SSWY+LR+ DPHNTE+  D + + +WLPV+ YVGG EH
Sbjct  476  VTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEH  534

Query  557  AILHLLYSRFFTKALRDRGLLNIREPFERLLTQGMVQGVTYRNPRTGRYVAPSEVSDENA  616
            A+LHLLY+RF  K L D G++  +EPF++L+ QGM+ G +YR++R G  VA   V   ++
Sbjct  535  AVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSR-GALVATDKVEKRDG  593

Query  617  PKDPVDGG-ELEVLFEKMSKSKYNGVDPAAVIDRYGADTARMFILFKAPPEKDLEWDDAD  675
            +   V+ G ELE    KMSKS  N V+P  V+++YGADT R++ +F +P +  + W + +
Sbjct  594  SFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEG  653

Query  676  VEGQFRFLQRLWRLIESVRSDDQDQLLGDPVDPPEGSGLSDKEGEIRRAVHTAIEAVSDD  735
            +EG  +FL+R+ RLI +    +++                   G + +  + ++ AV+++
Sbjct  654  LEGSRKFLDRVYRLITTKEITEEN------------------SGALDKVYNETVKAVTEQ  695

Query  736  LKGDFQFNTAISELMKLSNTLSGALPEASRAVQAEAVSALIRLLAPFAPHLAEEFWFSL-  794
            + ++ +FNTAI++LM + N+     ++    + ++   ++++L+APFAPHL+EE+W +L 
Sbjct  696  V-DQMKFNTAIAQLMVFVNA-----ANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALT  749

Query  795  GGQDSVHKQPWPLHDPAALVRDTVDLVIQVKGKVRGTITVPADCSKETLEELALASDVAE  854
            ++ +S+   PWP  D + LV + V++V+Q+KGKV++ + V+ D S+E L+E+ALA++  +
Sbjct  750  ASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQ  809

Query  855  RWLEGKPPRRVIVVPGKLVNLV  876
              + GK   +VI VP KLVN+V
Sbjct  810  AEIAGKDIIKVIAVPNKLVNIV  831

852) Sgly_2452 in NC_015172


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  566 bits (2138),  Expect = 2e-162, Method: Compositional matrix adjust.
 Identities = 360/859 (42%), Positives = 542/859 (64%), Gaps = 75/859 (8%)

Query  10   IEPKWQKKWVEERV-DQTSEDDRQKFYALAMFPYPSG-NLHMGHVRNYSIVDVIARFKRM  67
            IEPKWQ  W +++     ++  + KFYAL MFPYPSG  LH+GH   Y+  D+++RFKR 
Sbjct  9    IEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSRFKRA  68

Query  68   QGYHVLHPIGWDAFGLPAENAAIKNQTPPAEWTWKNIANMRSQLQEMGISYDWDREIATC  127
            QG +VLHP+GWDAFGLPAE+ A+     PAE T  NIAN + Q++ +G+SYDWDRE+ T 
Sbjct  69   QGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDREVNTT  128

Query  128  HPEYYRWTQWIFLELYQHGLAYKKKSAVNWCPSCNTVLANEQVV-DGACERCETEVTKKD  186
            +P+YY+WTQWIF  LY+ GLAY    +VNW     T +ANE+V+ DG+ ER    V +K 
Sbjct  129  DPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKP  188

Query  187  LEQWFFKITDYSEELLNDLEKLTGWPEKVKTMQRNWIGRSEGAQAKFKLEGRKEMITVFT  246
            + QW +KIT Y+E LL+DLE + +WPE +K MQRNWIG+S GA+  FK+ +    +TVFT
Sbjct  189  MRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFT  247

Query  247  TRLDTIFGVSCLVLAPEHPLVAELTKGTPYEKDVQAFIEKMKGLNEIARTSTETEKEGLF  306
            TR DT+FG +  VLAPEH+LV  +T +      V  +  +    +++ART    EK G+ 
Sbjct  248  TRPDTLFGATYAVLAPEHALVDAITTSDQ-AEAVADYKRQASLKSDLARTDLAKEKTGVW  306

Query  307  IGSRCINPLSGELVPIWIANYVLLDYGTGAVMGVPAHDQRDFEFAAKYNLPVTRVIRPED  366
             GS  INP++G  +P+WIA+YVL  YGTGA+M+VPAHD+RD EFA ++NL +  V+   +
Sbjct  307  TGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGN  366

Query  367  MPEEQIHLPMAAAYTENGMMVNSPDFNGMDNETARERMAgklekfklgekkINYRLRDWL  426
            + E        AA+TE+G+ +NS  ++G+D+ +A  +M   LE   +G+ ++ YRLRDWL
Sbjct  367  VEE--------AAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWL  418

Query  427  ISRQRYWGAPIPMVYCDQCGIVPVPVEQLPVRLPDDVVFKP---GDNPLTTSSSFLETVC  483
            +SRQRYWG PIP++  ++    +VP  +LP+ LP    ++P   G++PL+  +  LE V 
Sbjct  419  FSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE-VT  477

Query  484  PQCGGKARRETDTMDTFMCSSWYFLRYCDPRNAKEAFAAEAVDKWMNVDQYVGGVEHAIL  543
             + G K+RRET+TM     SSWY+LRY DP+N+      E + +W+ VD YVGG EHA+L
Sbjct  478  REDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVL  537

Query  544  HLLYSRFFTKVFRDFGYLHVDEPFENLLTQGMV----CMDG-------------------  580
            HLLY+RF  KV+ D+G +   EPF++L+ QGM+      D+                   
Sbjct  538  HLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFH  597

Query  581  -----------SKMSKSKGNVVSPEEIIGRFGADTARLFILFAAPPERDLEWSEQGVEGC  629
                       +KMSKS  NVV+P++++ ++GADT R++ +F +P +  + WSE+G+EG 
Sbjct  598  VETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGS  657

Query  630  YRFLNRVWRLAYQYHEAVRVREDVQTDSNETGEQGIKDIRRQIHLAIKKVTADVGTRFNF  689
             +FL+RV RL                 ++E  E+    + +  + ++K VT +V+ + +F
Sbjct  658  RKFLDRVYRL---------------ITTKEITEENSGALDKVYNETVKAVTEQVD-QMKF  701

Query  690  NTAISSVMELVNALYLYKEQPGADPASFKEGIETVLLLLSPFAPHITEEIWHEF-GHEES  748
            NTAI+ +M +VNA       +  +   F +     + L++PFAPH+ EE+W+ + +  ES
Sbjct  702  NTAIAQLMVFVNA-------ANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGES  754

Query  749  IHRRAWPQCDEDALIEDEVTVVLQINGKVRDRLQVPAAIPAEDLERLVRSSGKVIQLVEG  808
            I   +WP  DE  L+E++V +V+QI+GKV+ +L V+  ++ E+L+ +  ++ KV   + G
Sbjct  755  ISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAG  814

Query  809  KTIVKIITVPGKLVNVVVK  827
            K I+K+I+VP KLVN+V+K
Sbjct  815  KDIIKVIAVPNKLVNIVIK  833

853) leuS in NC_007954


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  566 bits (2136),  Expect = 3e-162, Method: Compositional matrix adjust.
 Identities = 363/873 (42%), Positives = 567/873 (65%), Gaps = 55/873 (6%)

Query  13   LYNPSEIEALVQKHWQEHKTFEVTEDESKEKFYCLSMFPYPSGR-LHMGHVRNYTIGDVV  71
            +Y+ + IE+  Q  W ++ TF    D SK KFY L MFPYPSG  LH+GH   YT  D++
Sbjct  3    FYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDIL  62

Query  72   ARYQRLQGKNVLQPIGWDSFGLPAENAAINNKTSPAPWTYENIDYMKNQLKLLGFGYDWS  131
            +R++R QG NVL+P+GWD+FGLPAE+ A++    PA  T ENI   K Q++ LGF+YDW 
Sbjct  63   SRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWD  122

Query  132  REIATCTPEYYRWEQWFFTKLYEKGMVYKKTSSVNWCPNDETVLANEQV-QDGCCWRCDT  190
            RE+ T  P+YY+W QW+FTKLYEKG+ Y    +VNW  +  T +ANE+V  DG   R + 
Sbjct  123  REVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGY  182

Query  191  PVIQKEIPQWFIKITDYAEELLNDIDTLDGWPEQVKAMQRNWIGRSEGIEMTFKVKDSEQ  250
            PV++K + QW +KIT YAE LL+D++ +D WPE +K MQRNWIG+S G ++TFKVKD+++
Sbjct  183  PVVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDK  241

Query  251  SFDIYTTRPDTLMGVTYVAIAAGHPLAEQAASTNPALAAFIEECKNADTTEAAMA----S  306
             F ++TTRPDTL G TY  +A+ H+L +  ++++ A A  + + K   +  + +A    +
Sbjct  242  DFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEA--VADYKRQASLKSDLARTDLA  299

Query  307  MEKKGVATGLEAVHPISGKLVPIWVANFVLMNYGTGAVMSVPAHDQRDYEFAKAYGLEMQ  366
             EK GV TG  A++P++GK +P+W+A++VL +YGTGA+M+VPAHD+RD EFAK + L++ 
Sbjct  300  KEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDII  359

Query  367  AVIKPADSEVDISKEAYTEKGVLFNSGTAFPELDGLEFQAAFDAIDARLTAEGKGKRQVN  426
            +V+  +    ++   A+TE G+  +  + F  LDGL+  +A+  +  +L AEG G+ +V 
Sbjct  360  PVLEGG----NVEEAAFTEDGL--HINSDF--LDGLDKASAIAKMVEWLEAEGVGNENVT  411

Query  427  YRLRDWGVSRQRYWGAPIPMVTLADGTVMPTPEDQLPVILP--EDVVMDGI-QSPIKADK  483
            YRLRDW  SRQRYWG PIP++   DGT  + PE +LP++LP   D+   G  +SP+    
Sbjct  412  YRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVT  471

Query  484  AWAETT-VDGKPAFRETDTFDTFMESSWYYARYCSPHADEML-DPAKANYWLPVDQYIGG  541
             W E T  DG  + RET+T      SSWYY RY  PH  E L D    + WLPVD Y+GG
Sbjct  472  DWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGG  531

Query  542  IEHACMHLLYFRFFHKLLRDAGLVNSNEPAKRLLTQGMVLADAYYYTNDKGARVWVSPLE  601
             EHA +HLLY RF HK+L D G+V ++EP ++L+ QGM+L+ +  Y + +GA V      
Sbjct  532  AEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS--YRDSRGALV-----A  584

Query  602  AEVVEKDDKGRVVKAVDSQGNELVYTGMSKMSKSKNNGIDPQTMVEKYGADTVRLFMMFA  661
            ++ VEK D G         G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF 
Sbjct  585  TDKVEKRD-GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFM  640

Query  662  SPPELTLEWQESGVEGAHRFIKRLWKL-ASDHVAAGPTEALDVSKLSSSQKALRRELHKT  720
            +P + ++ W E G+EG+++F+ R+ +L ++ +++   + ALD            +  + T
Sbjct  641  GPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALD------------KVYNET  688

Query  721  IAKVSDDIGRRQMFNTAVAAVMELMNHLSKAPQDSAQDRALLAEALSAVTRLLYPIIPHM  780
            +  V++++++ + FNTA+A +M ++N        + ++  L+++   +  +L+ P+ PH+
Sbjct  689  VKAVTEQVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHL  740

Query  781  SFTLWHEL-GNSNNIEDSRWPDVDEAALVEDSKLIVVQVNGKVRAKITVAADATKEAVEQ  839
            +  LW+ L +++++I    WP  DE+ LVE+   IVVQ++GKV+AK+ VA D ++E +++
Sbjct  741  GEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQE  800

Query  840  LGLDDEHVQKHLEGLTVRKVIYVPGKLLSLVAN  872
            ++L +E VQ ++ G  + KVI VP KL+++V +
Sbjct  801  VALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

854) leuS in NC_011830


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  565 bits (2135),  Expect = 3e-162, Method: Compositional matrix adjust.
 Identities = 367/864 (43%), Positives = 548/864 (64%), Gaps = 75/864 (8%)

Query  5    YLFSEIEPKWQKKWVDRKDYQAEEHSDKPKFYALAMFPYPSG-NLHMGHVRNYSIVDVIA  63
            Y  + IEPKWQ  W D   +++  ++ KPKFYAL MFPYPSG  LH+GH   Y+  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RFKRMRGYNVLHPIGWDSFGLPAENAAIKNQTPPAEWTWKNIANMKRQLQEMGISYDWER  123
            RFKR +G NVLHP+GWD+FGLPAE+ A+     PAE T  NIAN KRQ++ +G+SYDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVTTCHPDYYKFTQWIFLEFYKHGLVYKKKAGVNWCPSCATVLANEQVV-DGACERCDTA  182
            EV T +P+YYK TQWIF  +Y  GL Y     VNW    +T +ANE+V+ DG+ ER + +
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VTKKDLEQWFFKITDYAQVLLDDLEKLPGWPDKVKTMQKNWIGRSEGAEVEFDLENHGDK  242
            V +K + QW +KIT YA+ LL+DLE + +WP+ +K MQ+NWIG+S GA+V F + + +  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  IRVYTTRVDTIFGVSYVVLAPEHPLVQKLIAGTEYENDVQAFIERMKGLNEIARTSTETE  302
            + V+TTR DT+FG +Y VLAPEH+LV+ + ++ +  + V  +  +    +++ART    E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQ-AEAVADYKRQASLKSDLARTDLAKE  301

Query  303  KEGLFTGAYCINPYSGEKVPIWIANYVLFEYGTGAVMGVPAHDERDFEFAGKYKLPIKTV  362
            K G+ TG+Y INP +G  +P+WIA+YVL  YGTGA+M+VPAHDERD EFA +++L I  V
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  363  ILPEGTPVEEKDTPLQAAFVEEGMMVNSGEYDGLKNVEAWEKMCDKAEHDGFGERKVNFR  422
            +  EG  VEE      AAF E+G+ +NS+  DGL +  A  KM +  E +G G+ +V +R
Sbjct  362  L--EGGNVEE------AAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYR  413

Query  423  LRDWLISRQRYWGAPIPMIYCDHCGIVPVPQDQLPVMLPDDVVFK---AGENPLTTSESF  479
            LRDWL+SRQRYWG PIP+I  ++    +VP+ +LP++LP    ++   +GE+PL+     
Sbjct  414  LRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDW  473

Query  480  KQTICPTCGGKARRETDTMDTFMCSSWYFLRYTDPHNAQLPFAKEAADHWMNVDQYVGGV  539
             + +    G K+RRET+TM     SSWY+LRY DPHN++     E   +W+ VD YVGG 
Sbjct  474  LE-VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGA  532

Query  540  EHAILHLLYSRFFTKALRDFGYLKVDEPFANLLTQGMVCLGG------------------  581
            EHA+LHLLY+RF  K L D+G +   EPF +L+ QGM+ LG                   
Sbjct  533  EHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMI-LGTSYRDSRGALVATDKVEKR  591

Query  582  -----------------AKMSKSKGNVVSPEEIISKYGADTARLFILFAAPPERDLEWND  624
                             AKMSKS  NVV+P++++ +YGADT R++ +F +P +  + W++
Sbjct  592  DGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSE  651

Query  625  QGVEGCYRFLNRVWRLAAQYEEVLKTTGAGANEFGELDKAAKDMRRQTHQTIQRVTSDVG  684
            +G+EG  +FL+RV RL       + T     ++ G LDK         ++T++ VT +V+
Sbjct  652  EGLEGSRKFLDRVYRL-------ITTKEITEENSGALDKV-------YNETVKAVTEQVD  697

Query  685  ARFNFNTAVSAIMELVNALYLYKEQPQVNLAVAREALESILILLAPFAPHITEEIWSEL-  743
             + +FNTA++ +M +VNA       ++ +  +  +   +++ L+APFAPH+ EE+W  L 
Sbjct  698  -QMKFNTAIAQLMVFVNA-------ANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALT  749

Query  744  GHEDSIHSREWPQVDEEALVQEEVTVVLQINGKVKERIQVPAQISAAELEAQVRQLPRLG  803
            +  +SI    WP  DE  LV+++V +V+QI+GKVK ++ V+ ++S  EL+       ++ 
Sbjct  750  ASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQ  809

Query  804  EWTQGKQILKIVTVPGKLVNVVVK  827
                GK+I+K+++VP KLVN+V+K
Sbjct  810  AEIAGKDIIKVIAVPNKLVNIVIK  833

855) leuS in NC_007907


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  565 bits (2135),  Expect = 3e-162, Method: Compositional matrix adjust.
 Identities = 367/864 (43%), Positives = 548/864 (64%), Gaps = 75/864 (8%)

Query  5    YLFSEIEPKWQKKWVDRKDYQAEEHSDKPKFYALAMFPYPSG-NLHMGHVRNYSIVDVIA  63
            Y  + IEPKWQ  W D   +++  ++ KPKFYAL MFPYPSG  LH+GH   Y+  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RFKRMRGYNVLHPIGWDSFGLPAENAAIKNQTPPAEWTWKNIANMKRQLQEMGISYDWER  123
            RFKR +G NVLHP+GWD+FGLPAE+ A+     PAE T  NIAN KRQ++ +G+SYDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVTTCHPDYYKFTQWIFLEFYKHGLVYKKKAGVNWCPSCATVLANEQVV-DGACERCDTA  182
            EV T +P+YYK TQWIF  +Y  GL Y     VNW    +T +ANE+V+ DG+ ER + +
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VTKKDLEQWFFKITDYAQVLLDDLEKLPGWPDKVKTMQKNWIGRSEGAEVEFDLENHGDK  242
            V +K + QW +KIT YA+ LL+DLE + +WP+ +K MQ+NWIG+S GA+V F + + +  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  IRVYTTRVDTIFGVSYVVLAPEHPLVQKLIAGTEYENDVQAFIERMKGLNEIARTSTETE  302
            + V+TTR DT+FG +Y VLAPEH+LV+ + ++ +  + V  +  +    +++ART    E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQ-AEAVADYKRQASLKSDLARTDLAKE  301

Query  303  KEGLFTGAYCINPYSGEKVPIWIANYVLFEYGTGAVMGVPAHDERDFEFAGKYKLPIKTV  362
            K G+ TG+Y INP +G  +P+WIA+YVL  YGTGA+M+VPAHDERD EFA +++L I  V
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  363  ILPEGTPVEEKDTPLQAAFVEEGMMVNSGEYDGLKNVEAWEKMCDKAEHDGFGERKVNFR  422
            +  EG  VEE      AAF E+G+ +NS+  DGL +  A  KM +  E +G G+ +V +R
Sbjct  362  L--EGGNVEE------AAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYR  413

Query  423  LRDWLISRQRYWGAPIPMIYCDHCGIVPVPQDQLPVMLPDDVVFK---AGENPLTTSESF  479
            LRDWL+SRQRYWG PIP+I  ++    +VP+ +LP++LP    ++   +GE+PL+     
Sbjct  414  LRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDW  473

Query  480  KQTICPTCGGKARRETDTMDTFMCSSWYFLRYTDPHNAQLPFAKEAADHWMNVDQYVGGV  539
             + +    G K+RRET+TM     SSWY+LRY DPHN++     E   +W+ VD YVGG 
Sbjct  474  LE-VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGA  532

Query  540  EHAILHLLYSRFFTKALRDFGYLKVDEPFANLLTQGMVCLGG------------------  581
            EHA+LHLLY+RF  K L D+G +   EPF +L+ QGM+ LG                   
Sbjct  533  EHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMI-LGTSYRDSRGALVATDKVEKR  591

Query  582  -----------------AKMSKSKGNVVSPEEIISKYGADTARLFILFAAPPERDLEWND  624
                             AKMSKS  NVV+P++++ +YGADT R++ +F +P +  + W++
Sbjct  592  DGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSE  651

Query  625  QGVEGCYRFLNRVWRLAAQYEEVLKTTGAGANEFGELDKAAKDMRRQTHQTIQRVTSDVG  684
            +G+EG  +FL+RV RL       + T     ++ G LDK         ++T++ VT +V+
Sbjct  652  EGLEGSRKFLDRVYRL-------ITTKEITEENSGALDKV-------YNETVKAVTEQVD  697

Query  685  ARFNFNTAVSAIMELVNALYLYKEQPQVNLAVAREALESILILLAPFAPHITEEIWSEL-  743
             + +FNTA++ +M +VNA       ++ +  +  +   +++ L+APFAPH+ EE+W  L 
Sbjct  698  -QMKFNTAIAQLMVFVNA-------ANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALT  749

Query  744  GHEDSIHSREWPQVDEEALVQEEVTVVLQINGKVKERIQVPAQISAAELEAQVRQLPRLG  803
            +  +SI    WP  DE  LV+++V +V+QI+GKVK ++ V+ ++S  EL+       ++ 
Sbjct  750  ASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQ  809

Query  804  EWTQGKQILKIVTVPGKLVNVVVK  827
                GK+I+K+++VP KLVN+V+K
Sbjct  810  AEIAGKDIIKVIAVPNKLVNIVIK  833

856) leuS in NC_008577


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  565 bits (2134),  Expect = 4e-162, Method: Compositional matrix adjust.
 Identities = 372/868 (43%), Positives = 572/868 (66%), Gaps = 51/868 (5%)

Query  5    YNPSEIEALVQKHWHDNKTFEVTEDANKEKFYCLSMFPYPSGR-LHMGHVRNYTIGDVVA  63
            Y+ + IE+  Q  W DN TF    DA+K KFY L MFPYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RFQRLQGKNVLQPIGWDSFGLPAENAAINNKTAPAPWTYQNIEYMKNQLKLLGFGYDWSR  123
            RF+R QG NVL+P+GWD+FGLPAE+ A++    PA  T +NI   K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EIATCTPEYYRWEQWFFTKLYEKGLVYKKTASVNWCPNDETVLANEQV-QDGCCWRCDTP  182
            E+ T  P+YY+W QW+FTKLYEKGL Y    +VNW  +  T +ANE+V  DG   R + P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VEQKEIPQWFIKITAYAEELLNDIDTLDGWPEQVKTMQRNWIGRSEGVEMTFGVAGSDKS  242
            V +K + QW +KITAYAE LL+D++ +D WPE +K MQRNWIG+S G ++TF V ++DK 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  FDIYTTRPDTLMGVTYVAIAAGHPLAELAAQTNPELAQFIEECKNSTTSEADLA----TM  298
            F ++TTRPDTL G TY  +A+ H+L +  A T ++ A+ + + K  ++  +DLA    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVD--AITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  299  EKRGVATGLYAIHPITGKQVPIWAANFVLMNYGTGAVMSVPGHDQRDYEFAKKYNLPIEA  358
            EK GV TG YAI+P+ GK++P+W A++VL +YGTGA+M+VP+HD+RD EFAK++NL I +
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VIKPVDGELDISEAAYTEKGVLFNSGEFDGLDFDGAFNAIADKLVAEGKGKRQVNYRLRD  418
            V+       ++ EAA+TE G+ +NS+ +DGLD  +A+  + + L AEG G+ +V YRLRD
Sbjct  361  VLEGG----NVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  419  WGVSRQRYWGAPIPMVTLADGTVIPTPEDQLPVILP--EDVVMDGI-QSPIKADKEWAK-  474
            W  SRQRYWG PIP++   DGT  + PE +LP++LP   D+   G  +SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  475  TQVNGQDALRETDTFDTFMESSWYYARYCSPQADQML-DPTKANYWLPVDQYIGGIEHAC  533
            T+ +G  + RET+T      SSWYY RY  P+  + L D    + WLPVD Y+GG EHA 
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  534  MHLLYFRFFHKLLRDAGLVNSNEPAKQLLTQGMVLADAFYYTNDKGARVWVSPLDVVTTE  593
            +HLLY RF HK+L D G+V ++EP ++L+ QGM+L+ +  Y + +GA        +V+T+
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS--YRDSRGA--------LVATD  586

Query  594  KDDKGRVTKAIDKDGNELVYTGMCKMSKSKNNGIDPQVMVEKYGADTVRLFMMFASPPEL  653
            K +K R    ++ +  E +  +  KMSKS +N ++P+ +VE+YGADT+R++ MF +P + 
Sbjct  587  KVEK-RDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  654  TLEWQESGVEGAHRFIKRLWKL-ASDYVAQDNSEALDVSKLTSEQKALRREVHKTIAKVT  712
            ++ W E G+EG+++F+ R+ +L ++  ++++NS ALD            +  + T+  VT
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALD------------KVYNETVKAVT  693

Query  713  DDIGRRQMFNTAVAAVMELMNHLQKAPQTTGQDRAIIGEALTAVVRLLYPIIPHVSFTLW  772
            +++++ + FNTA+A +M ++N       ++ ++  ++++   + V+L+ P+ PH++  LW
Sbjct  694  EQVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELW  745

Query  773  NEL-GNTNSIEDSQWPVVDESALVEDSKLIVVQVNGKVRAKITVAADADQASVEALGMAD  831
            + L ++ +SI    WP  DES LVE+   IVVQ++GKV+AK+ VA D  +  ++ +++A+
Sbjct  746  QALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALAN  805

Query  832  EQVIKYLDGVTVRKVIYVPGKLLSIVAN  859
            E+V   + G  + KVI VP KL++IV +
Sbjct  806  EKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

857) leuS in NC_008322


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  565 bits (2133),  Expect = 4e-162, Method: Compositional matrix adjust.
 Identities = 371/868 (43%), Positives = 573/868 (67%), Gaps = 51/868 (5%)

Query  5    YNPSEIEALVQKHWHDNKTFEVTEDANKEKFYCLSMFPYPSGR-LHMGHVRNYTIGDVVA  63
            Y+ + IE+  Q  W DN TF    DA+K KFY L MFPYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RFQRLQGKNVLQPIGWDSFGLPAENAAINNKTAPAPWTYQNIEYMKNQLKLLGFGYDWSR  123
            RF+R QG NVL+P+GWD+FGLPAE+ A++    PA  T +NI   K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EIATCTPEYYRWEQWFFTKLYEKGLVYKKTASVNWCPNDETVLANEQV-QDGCCWRCDTP  182
            E+ T  P+YY+W QW+FTKLYEKGL Y    +VNW  +  T +ANE+V  DG   R + P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VEQKEIPQWFIKITAYAEELLNDIDTLDGWPEQVKTMQRNWIGRSEGVEMTFGVAGSDKS  242
            V +K + QW +KITAYAE LL+D++ +D WPE +K MQRNWIG+S G ++TF V ++DK 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  FDIYTTRPDTLMGVTYVAIAAGHPLAELAAQSNPELAQFIEECKNSTTSEADLA----TM  298
            F ++TTRPDTL G TY  +A+ H+L +  A + ++ A+ + + K  ++  +DLA    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVD--AITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  299  EKRGVATGLYAIHPISGKQVPIWAANFVLMNYGTGAVMSVPGHDQRDYEFAKKYNLPIEA  358
            EK GV TG YAI+P++GK++P+W A++VL +YGTGA+M+VP+HD+RD EFAK++NL I +
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VIKPVDGELDISEAAYTEKGVLFNSGEFDGLDFDGAFNAIADKLVAEGKGKRQVNYRLRD  418
            V+       ++ EAA+TE G+ +NS+ +DGLD  +A+  + + L AEG G+ +V YRLRD
Sbjct  361  VLEGG----NVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  419  WGVSRQRYWGAPIPMVTLADGTVIPTPEDQLPVILP--EDVVMDGI-QSPIKADKEWAK-  474
            W  SRQRYWG PIP++   DGT  + PE +LP++LP   D+   G  +SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  475  TQVNGQDALRETDTFDTFMESSWYYARYCSPQADQML-DPTKANYWLPVDQYIGGIEHAC  533
            T+ +G  + RET+T      SSWYY RY  P+  + L D    + WLPVD Y+GG EHA 
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  534  MHLLYFRFFHKLLRDAGLVNSNEPAKQLLTQGMVLADAFYYTNDKGARVWVSPLDVVTTE  593
            +HLLY RF HK+L D G+V ++EP ++L+ QGM+L+ +  Y + +GA        +V+T+
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS--YRDSRGA--------LVATD  586

Query  594  KDDKGRVTKAIDKDGNELVYTGMCKMSKSKNNGIDPQVMVEKYGADTVRLFMMFASPPEL  653
            K +K R    ++ +  E +  +  KMSKS +N ++P+ +VE+YGADT+R++ MF +P + 
Sbjct  587  KVEK-RDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  654  TLEWQESGVEGAHRFIKRLWKL-ASDYVAQDNSEALDVSKLTSEQKALRREVHKTIAKVT  712
            ++ W E G+EG+++F+ R+ +L ++  ++++NS ALD            +  + T+  VT
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALD------------KVYNETVKAVT  693

Query  713  DDIGRRQMFNTAVAAVMELMNHLQKAPQTTGQDRAIIGEALTAVVRLLYPIIPHVSFTLW  772
            +++++ + FNTA+A +M ++N       ++ ++  ++++   + V+L+ P+ PH++  LW
Sbjct  694  EQVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELW  745

Query  773  NEL-GNTNSIEDSQWPVVDESALVEDSKLIVVQVNGKVRAKITVAADADQASVEALGMAD  831
            + L ++ +SI    WP  DES LVE+   IVVQ++GKV+AK+ VA D  +  ++ +++A+
Sbjct  746  QALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALAN  805

Query  832  EQVIKYLDGVTVRKVIYVPGKLLSIVAN  859
            E+V   + G  + KVI VP KL++IV +
Sbjct  806  EKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

858) leuS in NC_019954


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  565 bits (2132),  Expect = 5e-162, Method: Compositional matrix adjust.
 Identities = 379/854 (45%), Positives = 576/854 (68%), Gaps = 64/854 (7%)

Query  3    YDFKLIESKWQKKWEENKIYKTSEDYNKPKYYCLEMFPYPSG-NLHMGHVRNYSIGDVVA  61
            YD   IE+KWQ  W +N  +KT+ D +KPK+Y L+MFPYPSG  LH+GH   Y+  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  62   RFKRMNGFNVLYPMGWDAFGLPAENAAIKHGIHPSKWTWSNIDNMRTQLKQLGLSYDWDR  121
            RFKR +G NVL PMGWDAFGLPAE+ A+  G +P+  T  NI N + Q++ LG+SYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  122  EVATCHPNYYKWTQWFFLLLYKRGLAYRKKAFVNWCPSCSTVLANEQVV-DGICDRCKTE  180
            EV T +PNYYKWTQW+F  LY +GLAY     VNW    +T +ANE+V+ DG  +R    
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  181  VVKKELEQWFFKITDYADELLNDLEKLHGWPDKVKTMQQNWIGRSEGVEFSFNAEKTGDK  240
            VV+K + QW +KIT YA+ LL+DLE ++ WP+ +K MQ+NWIG+S G + +F+   T+  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  241  ISVFTTRPDTVYGVSYVVLAPEHPLVETLSSGTEYEVSVKEFKKKMEKYNEIVRTSTETE  300
            ++VFTTRPDT++G +Y VLAPEH+LV++++++ + E +V ++K++    +++ RT    E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAE-AVADYKRQASLKSDLARTDLAKE  301

Query  301  KEGVFTGAYAINPMNGEKVPIWIANYVLLGYGTGAVMGVPAHDQRDFEFAKKYNLPIKVV  360
            K GV TG+YAINP+NG  +P+WIA+YVL +YGTGA+M+VPAHD+RD EFAK++NL I  V
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  361  ISPQDKTLHPDEMNEAFVDDGILVNSDRFNGMSNIEAIKAIGRYMEDIGIGKFEVNFKLR  420
            +   +        + AF +DG+ +NSD ++G+ +  AI  +   +E  G+G+ +V ++LR
Sbjct  362  LEGGNVE------EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  421  DWLISRQRYWGAPIPIIYCDKCGVVPVREEDLPVLLP--EDIQFNGRSTSPLQECDKFLN  478
            DWL+SRQRYWG PIPII  +     +V E +LP++LP   DI+ +G + SPL +    L+
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  479  TTCPKCHGL-ARRETDTMDTFVCSSWYFYRYTDARNEEEPFAREKVNYWMPVDQYIGGVE  537
             T  + +G+ +RRET+TM     SSWY+ RY D++N E     E ++ W+PVD Y+GG E
Sbjct  476  VT--REDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAE  533

Query  538  HAILHLMYSRFFNKVIRDAGLVTVDEPFENLLTQGMVL-------------------RDG  578
            HA+LHL+Y+RF +KV+ D G+V   EPF++L+ QGM+L                   RDG
Sbjct  534  HAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDG  593

Query  579  ---------------VKMSKSIGNTVSPEEIIEKYGADTARLFILFAAPPERDLEWSDQG  623
                            KMSKS+ N V+P++++E+YGADT R++ +F +P +  + WS++G
Sbjct  594  SFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEG  653

Query  624  VEGCFRFLQRVFRLVEELSNKLSNAGNFGEYDKDVRRITHKTIKKVTEDVSERFNFNTAI  683
            +EG  +FL+RV+RL+        N+G ++       ++ + T+K VTE+V ++ +FNTAI
Sbjct  654  LEGSRKFLDRVYRLITTKEITEENSGALD-------KVYNETVKAVTEQV-DQMKFNTAI  705

Query  684  SAIMEMVNGLNAHKDTNISKTVlkealdnlllllAPFAPHITEELWHTL-GHKESVHLMP  742
            + +M  VN+  A+K+ ++           ++ L+APFAPH+ EELW++L +  ES+  +P
Sbjct  706  AQLMVFVNA--ANKEDKLFSD----YAKGFVQLIAPFAPHLGEELWQALTASGESISYVP  759

Query  743  WPKYdanaivedeieiviqinGKVRDKMKISVEASEDEMREAALKQEKLLPLLEDkkivk  802
            WP YD + +VE+++EIV+QI+GKV+ K+ ++ + S +E++E AL +EK+ + + +K I+K
Sbjct  760  WPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIK  819

Query  803  vitvpkklvNIVVK  816
            VI+VP+KLVNIV+K
Sbjct  820  VIAVPNKLVNIVIK  833

859) TepRe1_1508 in NC_015519


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  565 bits (2132),  Expect = 5e-162, Method: Compositional matrix adjust.
 Identities = 379/854 (45%), Positives = 576/854 (68%), Gaps = 64/854 (7%)

Query  3    YDFKLIESKWQKKWEENKIYKTSEDYNKPKYYCLEMFPYPSG-NLHMGHVRNYSIGDVVA  61
            YD   IE+KWQ  W +N  +KT+ D +KPK+Y L+MFPYPSG  LH+GH   Y+  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  62   RFKRMNGFNVLYPMGWDAFGLPAENAAIKHGIHPSKWTWSNIDNMRTQLKQLGLSYDWDR  121
            RFKR +G NVL PMGWDAFGLPAE+ A+  G +P+  T  NI N + Q++ LG+SYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  122  EVATCHPNYYKWTQWFFLLLYKRGLAYRKKAFVNWCPSCSTVLANEQVV-DGICDRCKTE  180
            EV T +PNYYKWTQW+F  LY +GLAY     VNW    +T +ANE+V+ DG  +R    
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  181  VVKKELEQWFFKITDYADELLNDLEKLHGWPDKVKTMQQNWIGRSEGVEFSFNAEKTGDK  240
            VV+K + QW +KIT YA+ LL+DLE ++ WP+ +K MQ+NWIG+S G + +F+   T+  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  241  ISVFTTRPDTVYGVSYVVLAPEHPLVETLSSGTEYEVSVKEFKKKMEKYNEIVRTSTETE  300
            ++VFTTRPDT++G +Y VLAPEH+LV++++++ + E +V ++K++    +++ RT    E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAE-AVADYKRQASLKSDLARTDLAKE  301

Query  301  KEGVFTGAYAINPMNGEKVPIWIANYVLLGYGTGAVMGVPAHDQRDFEFAKKYNLPIKVV  360
            K GV TG+YAINP+NG  +P+WIA+YVL +YGTGA+M+VPAHD+RD EFAK++NL I  V
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  361  ISPQDKTLHPDEMNEAFVDDGILVNSDRFNGMSNIEAIKAIGRYMEDIGIGKFEVNFKLR  420
            +   +        + AF +DG+ +NSD ++G+ +  AI  +   +E  G+G+ +V ++LR
Sbjct  362  LEGGNVE------EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  421  DWLISRQRYWGAPIPIIYCDKCGVVPVREEDLPVLLP--EDIQFNGRSTSPLQECDKFLN  478
            DWL+SRQRYWG PIPII  +     +V E +LP++LP   DI+ +G + SPL +    L+
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  479  TTCPKCHGL-ARRETDTMDTFVCSSWYFYRYTDARNEEEPFAREKVNYWMPVDQYIGGVE  537
             T  + +G+ +RRET+TM     SSWY+ RY D++N E     E ++ W+PVD Y+GG E
Sbjct  476  VT--REDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAE  533

Query  538  HAILHLMYSRFFNKVIRDAGLVTVDEPFENLLTQGMVL-------------------RDG  578
            HA+LHL+Y+RF +KV+ D G+V   EPF++L+ QGM+L                   RDG
Sbjct  534  HAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDG  593

Query  579  ---------------VKMSKSIGNTVSPEEIIEKYGADTARLFILFAAPPERDLEWSDQG  623
                            KMSKS+ N V+P++++E+YGADT R++ +F +P +  + WS++G
Sbjct  594  SFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEG  653

Query  624  VEGCFRFLQRVFRLVEELSNKLSNAGNFGEYDKDVRRITHKTIKKVTEDVSERFNFNTAI  683
            +EG  +FL+RV+RL+        N+G ++       ++ + T+K VTE+V ++ +FNTAI
Sbjct  654  LEGSRKFLDRVYRLITTKEITEENSGALD-------KVYNETVKAVTEQV-DQMKFNTAI  705

Query  684  SAIMEMVNGLNAHKDTNISKTVlkealdnlllllAPFAPHITEELWHTL-GHKESVHLMP  742
            + +M  VN+  A+K+ ++           ++ L+APFAPH+ EELW++L +  ES+  +P
Sbjct  706  AQLMVFVNA--ANKEDKLFSD----YAKGFVQLIAPFAPHLGEELWQALTASGESISYVP  759

Query  743  WPKYdanaivedeieiviqinGKVRDKMKISVEASEDEMREAALKQEKLLPLLEDkkivk  802
            WP YD + +VE+++EIV+QI+GKV+ K+ ++ + S +E++E AL +EK+ + + +K I+K
Sbjct  760  WPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIK  819

Query  803  vitvpkklvNIVVK  816
            VI+VP+KLVNIV+K
Sbjct  820  VIAVPNKLVNIVIK  833

860) leuS in NC_011663


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  565 bits (2133),  Expect = 5e-162, Method: Compositional matrix adjust.
 Identities = 366/868 (43%), Positives = 570/868 (66%), Gaps = 51/868 (5%)

Query  5    YNPSEIEALVQKHWHDNKTFEVTEDANKEKFYCLSMFPYPSGR-LHMGHVRNYTIGDVVA  63
            Y+ + IE+  Q  W DN TF    DA+K KFY L MFPYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RFQRLQGKNVLQPIGWDSFGLPAENAAINNKTAPAPWTYENIEYMKNQLKLLGFGYDWSR  123
            RF+R QG NVL+P+GWD+FGLPAE+ A++    PA  T ENI   K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EIATCTPEYYRWEQWFFTKLYEKGLVYKKTASVNWCPNDETVLANEQV-QDGCCWRCDTP  182
            E+ T  P+YY+W QW+FTKLYEKGL Y    +VNW  +  T +ANE+V  DG   R + P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VEQKEIPQWFIKITAYAEELLNDIDTLDGWPDQVKTMQRNWIGRSEGVEMTFGVAGHDKS  242
            V +K + QW +KITAYAE LL+D++ +D WP+ +K MQRNWIG+S G ++TF V + DK 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  FDIYTTRPDTLMGVTYVAIAAGHPLAEIAAHTNPELAAFIDECKNSTTSEAELA----TM  298
            F ++TTRPDTL G TY  +A+ H+L  + A T ++ A  + + K  ++  ++LA    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHAL--VDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  299  EKRGVATGLFAIHPITGKQVPIWAANFVLMNYGTGAVMSVPGHDQRDFEFAKKYGLAIEA  358
            EK GV TG +AI+P+ GK++P+W A++VL +YGTGA+M+VP+HD+RD EFAK++ L I +
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VIKPVDGDVDISEAAYTEKGVLFNSGEFDGLDFEAGFNAIANKLVAEGKGKRQVNYRLRD  418
            V+     + ++ EAA+TE G+ +NS+ +DGLD  +++  + + L AEG G+ +V YRLRD
Sbjct  361  VL----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  419  WGVSRQRYWGAPIPMVTLADGTVIPTPADQLPVLLP--EDVVMDGI-QSPIKADKEWAK-  474
            W  SRQRYWG PIP++   DGT  + P  +LP++LP   D+   G  +SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  475  TQVNGQDALRETDTFDTFMESSWYYARYCSPHADEML-DPAKANYWLPVDQYIGGIEHAC  533
            T+ +G  + RET+T      SSWYY RY  PH  E L D    + WLPVD Y+GG EHA 
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  534  MHLLYFRFFHKLLRDAGLVNSNEPAKQLLTQGMVLADAFYYINEKGARVWVSPLDVATTE  593
            +HLLY RF HK+L D G+V ++EP ++L+ QGM+L+ +  Y + +GA        + +T+
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS--YRDSRGA--------LVATD  586

Query  594  KDDKGRITKAIDKDGNELVYTGMSKMSKSKNNGIDPQVMVEKYGADTVRLFMMFASPPEL  653
            K +K R    ++ +  E +  + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P + 
Sbjct  587  KVEK-RDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  654  TLEWQESGVEGAHRFIKRLWKL-ANEHVNQDNSEALDVSTLTSDQKALRREVHKTIAKVT  712
            ++ W E G+EG+++F+ R+ +L +  ++ ++NS ALD            +  + T+  VT
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALD------------KVYNETVKAVT  693

Query  713  DDIGRRQMFNTAVAAVMELMNHLQKAPQTTGQDNAIIGEALSAIVRLLYPIIPHVSFNLW  772
            +++++ + FNTA+A +M ++N       ++ +++ ++++   ++V+L+ P+ PH++ +LW
Sbjct  694  EQVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELW  745

Query  773  NEL-GNASNIEDSQWPVVDEAALVEDSKLIVVQVNGKVRAKITVAADADKESVEALGMID  831
            + L +++ +I    WP  DE+ LVE+   IVVQ++GKV+AK+ VA D  +E ++ +++ +
Sbjct  746  QALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALAN  805

Query  832  EHVIKYLDGLTVRKVIYVPGKLLSIVAN  859
            E V   + G  + KVI VP KL++IV +
Sbjct  806  EKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

861) leuS in NC_009706


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  564 bits (2128),  Expect = 1e-161, Method: Compositional matrix adjust.
 Identities = 359/832 (44%), Positives = 536/832 (65%), Gaps = 58/832 (6%)

Query  18   NIYTFDEKKSSKKLYTLEMFSYPSGSNLHAGHWFNYAPVDSWARMKRMQGYNVFQPMGFD  77
            + +  +   S  K+Y+L+MF+YPSG+ LH GH   Y++ D  +R KR QG NV++PMG D
Sbjct  21   HTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSRFKRAQGHNVLHPMGWD  80

Query  78   AFGLPAENYAIKTGIHPKDSTEKNIDTMEKQLKSMGAMFNWENEVVTCRPDYYKWNQWLF  137
            AFGLPAE+YA+ TG +P + T  NI    +Q++++G  ++W+ EV T  P+YYKW QW+F
Sbjct  81   AFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIF  140

Query  138  LQLYKHDLAYRKNAPVNWCPSCNTVLANEQV-KEGECERCGTEVTKKDLTQWFFKITDYT  196
             +LY  +LAY  + PVNW     T +ANE+V  +G  ER G  V +K + QW +KIT Y+
Sbjct  141  TKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYA  200

Query  197  EELLKDLDNIDWPEKTKAMQRHWMGKSTGTDVTFKVADSDIKFNVFTTRVDTLFGVTYVV  256
            E LL DL+++DWPE  K MQR+W+GKSTG++VTFKV D+D  F VFTTR DTLFG TY V
Sbjct  201  ERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAV  260

Query  257  ISPENDLVDSVTkeeykeeiekyreaakkQTDIERQSITREKTGVSTGSYAINPINGRKV  316
            ++PE+ LVD++T  +  E +  Y+  A  ++D+ R  +++EKTGV TGSYAINP+NG+ +
Sbjct  261  LAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAINPVNGKEM  320

Query  317  PIWIGDYVLNTYGTGAVMAVPAHDERDFEFATKYKLPIERVIEGGS--SLPYVEYGKMIN  374
            P+WI+DYVL +YGTGA+MAVPAHDERD EFA +++L I  V+EGG+    ++ E G  IN
Sbjct  321  PVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEAAFTEDGLHIN  380

Query  375  SDKFNGLYTPEGKEAVTKELENIGLGSGKTNYRLRDWLVSRQRYWGTPIPIIYCKKCGTV  434
            SD ++GL  + +   +   LE  G+G+ +  YRLRDWL SRQRYWG PIPII      + 
Sbjct  381  SDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTST  440

Query  435  PVPESDLPVELPYNVQFSPDGK--SPLLKSEEFMNTTCPICGEPAKREADTLDTFVCSSW  492
            +VPES+LP+ LP   ++ P G   SPL +  + ++ T    G  ++RE++T+     SSW
Sbjct  441  AVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRE-DGVKGRRETNTMPQWAGSSW  499

Query  493  YYLRYADNKNTEKAFDKDKINKLLPVDMYVGGPEHACMHLLYARFITKALRDMGFLNFDE  552
            YYLRY D  NTEK  D + +++ LPVD+YVGG+EHA +HLLYARF  K L D+G +   E
Sbjct  500  YYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKE  559

Query  553  PFLSLRHQGLILGP---------------------------------DGQKMSKSKGNTI  579
            PF  L +QG+ILG                                     KMSKS  N +
Sbjct  560  PFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVV  619

Query  580  SPDDCIQKYGSDVFRMYLMFGFDYAEGGAWNDDGIKSMSKFVDRIERIVGNIKELINSGK  639
            +PDD +++YG+D +R+Y MF      + AW+++G+ +  KF+DR+ R++           
Sbjct  620  NPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITT---------  670

Query  640  NFKNSMDAAEKELNYSRNYSIKSVSEDAGKFQFNTAIARIMEFTNSLYKYIQEDTKNISL  699
              K+  +     L+   N ++K+V+E+ ++ +FNTAIA++M F       ++   K+  L
Sbjct  671  --KEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVF-------VNAANKEDKL  721

Query  700  LKDTILDFIKIIAPFAPHFAEEQWEVLGQKYSIFN-EKWPEFDPKALVKEEVEIAIQING  758
            + D   +F+++IAPFAPH++EE W+ L      ++   WP +D   LV ++VEI +QI+G
Sbjct  722  FSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKG  781

Query  759  KIKAKINIPTNLSDEQIKELSISNDNIKPLLEGKNikkvivvkGRLVNIVVK  810
            K+KAK+ ++ +LS E+++E++++N+++++ + GK+I KVI V  +LVNIV+K
Sbjct  782  KVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

862) leuS in NC_011837


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  564 bits (2128),  Expect = 1e-161, Method: Compositional matrix adjust.
 Identities = 359/832 (44%), Positives = 536/832 (65%), Gaps = 58/832 (6%)

Query  18   NIYTFDEKKSSKKLYTLEMFSYPSGSNLHAGHWFNYAPVDSWARMKRMQGYNVFQPMGFD  77
            + +  +   S  K+Y+L+MF+YPSG+ LH GH   Y++ D  +R KR QG NV++PMG D
Sbjct  21   HTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSRFKRAQGHNVLHPMGWD  80

Query  78   AFGLPAENYAIKTGIHPKDSTEKNIDTMEKQLKSMGAMFNWENEVVTCRPDYYKWNQWLF  137
            AFGLPAE+YA+ TG +P + T  NI    +Q++++G  ++W+ EV T  P+YYKW QW+F
Sbjct  81   AFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIF  140

Query  138  LQLYKHDLAYRKNAPVNWCPSCNTVLANEQV-KEGECERCGTEVTKKDLTQWFFKITDYT  196
             +LY  +LAY  + PVNW     T +ANE+V  +G  ER G  V +K + QW +KIT Y+
Sbjct  141  TKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYA  200

Query  197  EELLKDLDNIDWPEKTKAMQRHWMGKSTGTDVTFKVADSDIKFNVFTTRVDTLFGVTYVV  256
            E LL DL+++DWPE  K MQR+W+GKSTG++VTFKV D+D  F VFTTR DTLFG TY V
Sbjct  201  ERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAV  260

Query  257  ISPENDLVDSVTkeeykeeiekyreaakkQTDIERQSITREKTGVSTGSYAINPINGRKV  316
            ++PE+ LVD++T  +  E +  Y+  A  ++D+ R  +++EKTGV TGSYAINP+NG+ +
Sbjct  261  LAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAINPVNGKEM  320

Query  317  PIWIGDYVLNTYGTGAVMAVPAHDERDFEFATKYKLPIERVIEGGS--SLPYVEYGKMIN  374
            P+WI+DYVL +YGTGA+MAVPAHDERD EFA +++L I  V+EGG+    ++ E G  IN
Sbjct  321  PVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEAAFTEDGLHIN  380

Query  375  SDKFNGLYTPEGKEAVTKELENIGLGSGKTNYRLRDWLVSRQRYWGTPIPIIYCKKCGTV  434
            SD ++GL  + +   +   LE  G+G+ +  YRLRDWL SRQRYWG PIPII      + 
Sbjct  381  SDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTST  440

Query  435  PVPESDLPVELPYNVQFSPDGK--SPLLKSEEFMNTTCPICGEPAKREADTLDTFVCSSW  492
            +VPES+LP+ LP   ++ P G   SPL +  + ++ T    G  ++RE++T+     SSW
Sbjct  441  AVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRE-DGVKGRRETNTMPQWAGSSW  499

Query  493  YYLRYADNKNTEKAFDKDKINKLLPVDMYVGGPEHACMHLLYARFITKALRDMGFLNFDE  552
            YYLRY D  NTEK  D + +++ LPVD+YVGG+EHA +HLLYARF  K L D+G +   E
Sbjct  500  YYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKE  559

Query  553  PFLSLRHQGLILGP---------------------------------DGQKMSKSKGNTI  579
            PF  L +QG+ILG                                     KMSKS  N +
Sbjct  560  PFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVV  619

Query  580  SPDDCIQKYGSDVFRMYLMFGFDYAEGGAWNDDGIKSMSKFVDRIERIVGNIKELINSGK  639
            +PDD +++YG+D +R+Y MF      + AW+++G+ +  KF+DR+ R++           
Sbjct  620  NPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITT---------  670

Query  640  NFKNSMDAAEKELNYSRNYSIKSVSEDAGKFQFNTAIARIMEFTNSLYKYIQEDTKNISL  699
              K+  +     L+   N ++K+V+E+ ++ +FNTAIA++M F       ++   K+  L
Sbjct  671  --KEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVF-------VNAANKEDKL  721

Query  700  LKDTILDFIKIIAPFAPHFAEEQWEVLGQKYSIFN-EKWPEFDPKALVKEEVEIAIQING  758
            + D   +F+++IAPFAPH++EE W+ L      ++   WP +D   LV ++VEI +QI+G
Sbjct  722  FSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKG  781

Query  759  KIKAKINIPTNLSDEQIKELSISNDNIKPLLEGKNikkvivvkGRLVNIVVK  810
            K+KAK+ ++ +LS E+++E++++N+++++ + GK+I KVI V  +LVNIV+K
Sbjct  782  KVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

863) leuS in NC_009767


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  564 bits (2129),  Expect = 1e-161, Method: Compositional matrix adjust.
 Identities = 379/875 (44%), Positives = 555/875 (64%), Gaps = 80/875 (9%)

Query  14   DPAIEPKWREFWEREGIFKAGRRAGAPRRYILEMFPYPSG-DLHIGHLKNYVIGDALTRY  72
            + AIEPKW+ FW  +  FK+G  A+ P+ Y L+MFPYPSG +LH+GH   Y   D L+R+
Sbjct  6    HTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSRF  65

Query  73   YVIRGYDVLHPFGWDAFGLPAENAAIKYGRHPREWTYGNIAESKKSLEIAGIMYDWSREV  132
               +G +VLHP GWDAFGLPAE+ A+  G +P E T  NIA+ K+ ++  G+ YDW REV
Sbjct  66   KRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDREV  125

Query  133  TTCDPDYYRWNQWLFLLLYRKGLAYRAKATVNWDPVDQTVLANEQVDAEGRSWRSGAKVE  192
             T DP+YY+W QW+F  LY KGLAY A   VNW     T +ANE+V ++G S R+G  V 
Sbjct  126  NTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVV  185

Query  193  KRELEQWFFRITAYAERLLNDLDKLDKWPENVKTMQRNWIGRSEGAEVTFlalppgadlh  252
            ++ + QW ++ITAYAERLL+DL+ +D WPE++K MQRNWIG+S GA+VTF     + D+ 
Sbjct  186  RKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKDF-  243

Query  253  appppdaeplVVFTTRPDTLWGATFMVLAPEHPLVSKLTAPERRAEVEAYIARARMESEI  312
                       VFTTRPDTL GAT+ VLAPEH+LV  +T++++   V  Y  +A + S++
Sbjct  244  ----------TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDL  293

Query  313  ERTSATREKTGVFLGSYAINPVNDERIPIWIADYVLMGYGAGAIMAVPAHDERDFAFARQ  372
             RT  ++EKTGV  GSYAINPVN+  +P+WIADYVL +YG+GAIMAVPAHDERD  FA+Q
Sbjct  294  ARTDLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQ  353

Query  373  FGLPVRVVVQPPGETLDGATMTEAWPGDGVMVNSGPINGLPVGKGEGQSVKATIAWLEAN  432
            F L +  V++  G  ++ A+ TE    DG+ +NS+ ++GL    + + ++   + WLEA+
Sbjct  354  FNLDIIPVLE--GGNVEEAAFTE----DGLHINSDFLDGL----DKASAIAKMVEWLEAE  403

Query  433  GKGKGTVTYRLRDWLISRQRYWGTPIPMLHLPDGTIKPVPEDQLPVVLPEVQDYLPKGK-  491
            G G+  VTYRLRDWL+SRQRYWG PIP++H  DGT  +VPE +LP+VLP  +D  P G  
Sbjct  404  GVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTG  463

Query  492  -SPLAAAESWVNTIDPETGQPARRDTDTMDTFVDSSWYFLRFCDARNDREIFSREAAHRW  550
             SPLA    W++ +  E G  +RR+T+TM    +SSWY+LR+ D++N   +   E   +W
Sbjct  464  ESPLANVTDWLE-VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQW  522

Query  551  MPVDQYIGGVEHAILHLLYARFITKVLYDEGLVPDDEPFRALFTQGMVQ----RRVRTPL  606
            +PVD Y+GG EHA+LHLLYARF  KVLYD G+VP  EPF+ LF QGM+     R  R +L
Sbjct  523  LPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGAL  582

Query  607  EVVAPGMVRFPEELRRKLELPADAQSLDQARALLKERGYTLEEESNGGFTAVSGPVTMSK  666
                               +++D     ++  +  E G  LE+          +P  MSK
Sbjct  583  -------------------VATDKVEKRDGSFFHVETGEELEQ----------APAKMSK  613

Query  667  SAGNGIPVGPFVRQYGSDVARIVVLFAAPPENSMEWTDEGVAGAQRFLNRIVALFSPDRE  726
            S  N +  +  V QYG+D  R+  +F +P + S+ W++EG+ G+++FL+R+  L++    
Sbjct  614  SLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTK--  671

Query  727  EIVAALNSGNGAAPEGEERALYRKLHETIRKVTLDTEQFRFNTAIAALMELLNEASRYRS  786
                          E +  AL +  +ET++ VT + +Q +FNTAIA LM ++N A+    
Sbjct  672  -----------EITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAAN----  716

Query  787  EAGRVTPVFAQTAATFARLLSPFAPHLAEEL-HSWCGGTGSVYDTGWPEWDEAALALDEV  845
               +   +F++ A  F +L++PFAPHL+EEL ++  ++  S+    WP  DE+ L  ++V
Sbjct  717  ---KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDV  773

Query  846  EIVLQVNGKLRGRIMAPANADEQQLREWALTNPRV  880
            EIV+Q++GK++++++ + +   ++L+E AL+N +V
Sbjct  774  EIVVQIKGKVKAKLVVAKDLSREELQEVALANEKV  808

864) Desmer_4033 in NC_018515


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  564 bits (2128),  Expect = 1e-161, Method: Compositional matrix adjust.
 Identities = 364/871 (42%), Positives = 560/871 (65%), Gaps = 82/871 (9%)

Query  5    YSFPEIESKWQKEWVDSKAYRTEENSTKPKYYALAMFPYPSG-DLHMGHVRNYSIADVIA  63
            Y    IE+KWQ  W D+ +++T  +++KPK+YAL MFPYPSG +LH+GH   Y+ +D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYKRMTGHNVLHPIGWDAFGLPAENAAIKNQTPPADWTWKNIANMRRQLQEMGISYDWDR  123
            R+KR  GHNVLHP+GWDAFGLPAE+ A+     PA+ T  NIAN +RQ++ +G+SYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVATCHPGYYKWTQWLFLEFYKHGLVYKKKADVNWCPSCATVLANEQVV-DGGCERCDSL  182
            EV T +P YYKWTQW+F  +Y  GL Y     VNW    +T +ANE+V+ DG  ER +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VTKKSLEQWFFKITDYAEVLLQDLDKLPGWPEKVKTMQRNWIGRSEGVELKFPLEERPEK  242
            V +K++ QW +KIT YAE LL+DL+ + +WPE +K MQRNWIG+S G ++ F + +    
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  ISVYTTRIDTIYGVSYVVLAPEHPLVLELVKGTEYEAETVAFIEKMKGLN-EIARTSTDA  301
            ++V+TTR DT++G +Y VLAPEH+LV  +  +   +AE+VA   +  +L+ ++ART    
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSD--QAEAVADYKRQASLKSDLARTDLAK  300

Query  302  EKEGLFTGAYCLNPLSGKKVPIWIANYVLLEYGTGAVMGVPAHDERDFEFATKYKLEIKT  361
            EK G+ TG+Y +NP++GK +P+WIA+YVL  YGTGA+M+VPAHDERD EFA +++L+I  
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDI--  358

Query  362  VISALGSSPVEKDQPPKAVYSGEGVMVNSDAFDGLGSEEALEKIADEAERQGIGQRKVNF  421
             I+ L ++ VE      A ++ +G+ +NSD +DGL+   A+ K+ +  E +G+G+ +V +
Sbjct  359  -IPVLEGGNVE-----EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTY  412

Query  422  RLRDWLISRQRYWGAPIPMIYCDSCGIVPVPDEQLPVMLPPDVVFK---SGENPLATSSS  478
            RLRDWL+SRQRYWG PIP+I  +     +VP+ +LP++LP    ++   +GE+PLA  + 
Sbjct  413  RLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTD  472

Query  479  FIETTCPKCGGAARRETDTMDTFACSSWYFLRYTDPRNDQEVFSKNAVNQWMNVDQYVGG  538
             +E T    G  +RRET+TM   A SSWY+LRY DP+N + +   + ++QW+ VD YVGG
Sbjct  473  WLEVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGG  531

Query  539  VEHAILHLLYARFFTKGLRDFGYLEADEPFQNLLTQGMV---------------------  577
             EHA+LHLLYARF  K L D+G + + EPFQ+L+ QGM+                     
Sbjct  532  AEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKR  591

Query  578  -------------CMNGSKMSKSKGNVVSPGAIIGKYGADTARLFILFAAPPERDLEWSD  624
                             +KMSKS  NVV+P+ ++ +YGADT R++ +F +P +  + WS+
Sbjct  592  DGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSE  651

Query  625  QGVEGCYRFLNRIWRLVAQYEPLLRKTsgagsessdsagKWADLDAAGKEMRRQTHLAIQ  684
            +G+EG  +FL+R+ RL++  E                       +  +  + +  + +++
Sbjct  652  EGLEGSRKFLDRVYRLITTKEI---------------------TEENSGALDKVYNETVK  690

Query  685  RVTTDIGKRYNFNTAISTIMEWVNALYIYKEQPTANPEVGrealerilillapiapHITE  744
             VT ++++  +FNTAI+ +M       ++ + +  +  +  +    ++ L+AP+APH+ E
Sbjct  691  AVTEQVDQM-KFNTAIAQLM-------VFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGE  742

Query  745  ELWREL-GHTESIHLQSWPEVDEAALVQDEVTVILQVNGKVRERIQVAADISAPELEKLV  803
            ELW+ L +  ESI   +WP  DE+ LV+++V +++Q++GKV+ ++ VA D+S  EL+ + 
Sbjct  743  ELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVA  802

Query  804  LAQPKVTEWTDGKTIVKVITVPGKLVNIVVK  834
            LA+ KV     GK I+KVI+VP KLVNIV+K
Sbjct  803  LANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

865) leuS in NC_009665


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  564 bits (2131),  Expect = 7e-162, Method: Compositional matrix adjust.
 Identities = 367/868 (43%), Positives = 569/868 (66%), Gaps = 51/868 (5%)

Query  20   YNPSEIEALVQKHWHDNKTFEVTEDANKEKFYCLSMFPYPSGR-LHMGHVRNYTIGDVVA  78
            Y+ + IE+  Q  W DN TF    DA+K KFY L MFPYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  79   RFQRLQGKNVLQPIGWDSFGLPAENAAINNKTAPAPWTYENIEYMKNQLKLLGFGYDWSR  138
            RF+R QG NVL+P+GWD+FGLPAE+ A++    PA  T ENI   K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  139  EIATCTPEYYRWEQWFFTKLYEKGLVYKKTASVNWCPNDETVLANEQV-QDGCCWRCDTP  197
            E+ T  P+YY+W QW+FTKLYEKGL Y    +VNW  +  T +ANE+V  DG   R + P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  198  VEQKEIPQWFIKITAYAEELLNDIDTLDGWPEQVKTMQRNWIGRSEGVEMTFGVAGHDKS  257
            V +K + QW +KITAYAE LL+D++ +D WPE +K MQRNWIG+S G ++TF V + DK 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  258  FDIYTTRPDTLMGVTYVAIAAGHPLAEIAAQTNPELAAFIDECKNSTTSEAELA----TM  313
            F ++TTRPDTL G TY  +A+ H+L  + A T ++ A  + + K  ++  ++LA    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHAL--VDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  314  EKRGVATGLFAIHPITGKQVPIWAANFVLMNYGTGAVMSVPGHDQRDFEFAKKYGLAIEA  373
            EK GV TG +AI+P+ GK++P+W A++VL +YGTGA+M+VP+HD+RD EFAK++ L I +
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  374  VIKPVDGDVDISEAAYTEKGVLFNSGEFDGLDFEAGFNAIANKLVAEGKGKRQVNYRLRD  433
            V+     + ++ EAA+TE G+ +NS+ +DGLD  +++  + + L AEG G+ +V YRLRD
Sbjct  361  VL----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  434  WGVSRQRYWGAPIPMVTLADGTVIPTPADQLPVLLP--EDVVMDGI-QSPIKADKEWAK-  489
            W  SRQRYWG PIP++   DGT  + P  +LP++LP   D+   G  +SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  490  TQVNGQDALRETDTFDTFMESSWYYARYCSPHADEML-DPAKANYWLPVDQYIGGIEHAC  548
            T+ +G  + RET+T      SSWYY RY  PH  E L D    + WLPVD Y+GG EHA 
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  549  MHLLYFRFFHKLLRDAGLVNSNEPAKQLLTQGMVLADAFYYINEKGARVWVSPLDVATTE  608
            +HLLY RF HK+L D G+V ++EP ++L+ QGM+L+ +  Y + +GA        + +T+
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS--YRDSRGA--------LVATD  586

Query  609  KDDKGRITKAIDKDGNELVYTGMSKMSKSKNNGIDPQVMVEKYGADTVRLFMMFASPPEL  668
            K +K R    ++ +  E +  + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P + 
Sbjct  587  KVEK-RDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  669  TLEWQESGVEGAHRFIKRLWKL-ANEHVNQANSEALDVSTLTSDQKALRREVHKTIAKVT  727
            ++ W E G+EG+++F+ R+ +L +  ++ + NS ALD            +  + T+  VT
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALD------------KVYNETVKAVT  693

Query  728  DDIGRRQMFNTAVAAVMELMNHLQKAPQTTGQDRAIIGEALSAIVRLLYPIIPHVSFNLW  787
            +++++ + FNTA+A +M ++N       ++ ++  ++++   ++V+L+ P+ PH++ +LW
Sbjct  694  EQVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELW  745

Query  788  NEL-GNASNIEDSQWPVVDEAALVEDSKLIVVQVNGKVRAKITVAADADKESVEALGMSD  846
            + L +++ +I    WP  DE+ LVE+   IVVQ++GKV+AK+ VA D  +E ++ +++++
Sbjct  746  QALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALAN  805

Query  847  EHVIKYLDGLTVRKVIYVPGKLLSIVAN  874
            E V   + G  + KVI VP KL++IV +
Sbjct  806  EKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

866) Sthe_1438 in NC_013523


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  564 bits (2130),  Expect = 8e-162, Method: Compositional matrix adjust.
 Identities = 371/850 (44%), Positives = 547/850 (65%), Gaps = 62/850 (7%)

Query  13   YEPHAIEEKWRKIWDETGIYRVVEDPNRPKWYHLTMYPYPSG-DLHIGHWYAMAPSDAAA  71
            Y+  AIE KW+ +W +   ++   D+++PK Y L M+PYPSG +LH+GH  + +++D  +
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  72   RFKRMSGYNVLFPMGFDAFGLPAENAAITRGIHPFKWTMDNIERMRRQLRSMGAMFDWSR  131
            RFKR  G NVL PMG DAFGLPAE+ A+  G +P   T +NI   +RQ+ ++G  +DW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  132  EVVTCLPDYYRWNQWFFLQFYKNGLAYRASAPVWWCPKDQTVLANEQVI-DGRCERCGTE  190
            EV T  P+YY+W QW+F ++Y +GLAY A  PV W     T +ANE+V+ DG  ER G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  191  VYRRDLEQWFFRITKYAEELL-NFDGIEWPERVMTMQRNWIGRSEGARVRFQT-AVGDAI  248
            V R+ + QW ++IT YAE LL +++ ++WPE +  MQRNWIG+S GA V F+    +  +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  249  EIFTTRPDTLWGATFMVLAPEHPLVERLTSPEQRAAVEAYVDQTRRETDIERTATDREKT  308
             +FTTRPDTL GAT+ VLAPEH+LV+ +T+++Q  AV  Y  Q+   +D+ RT   +EKT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  309  GVFTGGYAINPVNGAQIPVWIADYVLMSYGTGAIMAVPAHDQRDFEFARKYDLPIQVVIQ  368
            GV TG+YAINPVNG ++PVWIADYVL SYGTGAIMAVPAHD+RD EFA++++L I  V+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL-  362

Query  369  PEGEPLDPATMTEAYPGDGVMVNSGPFDGTPTAGGEAVRRVTEWLEEQGLGSHAVTYRLR  428
             EG  ++ A    A+  DG+ +NS+ +DG   A+  A+ ++ EWLE +G+G++ VTYRLR
Sbjct  363  -EGGNVEEA----AFTEDGLHINSDFLDGLDKAS--AIAKMVEWLEAEGVGNENVTYRLR  415

Query  429  DWLISRQRYWGTPIPIVYCDKCGTVPVPEDQLPVLLPEDAEFTPTGV--SPLKTDERFVN  486
            DWL+SRQRYWG PIPI+  +   + +VPE +LP++LP   ++ P+G   SPL      ++
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  487  TTCPECGGPARRETDTMDTFVDSSWYQYRYVSPHEADRPFDPDAIAYWTPVDQYTGGIEH  546
             T  + G  +RRET+TM    +SSWY  RY+ PH++++  D + +  W PVD Y GG EH
Sbjct  476  VTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEH  534

Query  547  ATMHLMYARFFTKALRDLGLLPFDEPFLRLFNQGIILG----------------------  584
            A +HL+YARF  K L DLG++P  EPF +LFNQG+ILG                      
Sbjct  535  AVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGS  594

Query  585  -----------EDNEKMSKSRGNVVDPDDLVAQLGADTVRLYLMFIAPWEQGGPWSSRGI  633
                       +   KMSKS  NVV+PDD+V Q GADT+R+Y MF++P + + +WS  G+
Sbjct  595  FFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGL  654

Query  634  AGVERFVRRVWTIVTETADTPADGPDGEAAHKLRKITHRTIKAVTEDISTFQFNTMVARL  693
             G  +F+ RV  ++T    T  ++        L K+ + T+KAVTE++   +FNT +A+L
Sbjct  655  EGSRKFLDRVYRLITTKEITEENSGA------LDKVYNETVKAVTEQVDQMKFNTAIAQL  708

Query  694  MEFVNELSSLRDTEVVRTEAWREAMRTLVLLLAPSTPYLAEELWERLGQP-YSVHQQSWP  752
            M FVN  ++ ++  +       +  + +V L+AP +P L+EELW+ L  +  S+   +WP
Sbjct  709  MVFVN--AANKEDKLF-----SDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWP  761

Query  753  QYDPELAAAEMIELVVQVNGKVRDRLEVPADITEERAIELATASNRVREHLQGRTVRRTI  812
             YD      + +E+VVQ++GKV+ +L V+ D++ E   E+A A+++V+ ++ G+ + + I
Sbjct  762  SYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVI  821

Query  813  YVPGRLVNIV  822
             VP +LVNIV
Sbjct  822  AVPNKLVNIV  831

867) Kfla_2370 in NC_013729


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  563 bits (2127),  Expect = 1e-161, Method: Compositional matrix adjust.
 Identities = 356/847 (43%), Positives = 531/847 (63%), Gaps = 56/847 (6%)

Query  17   YDFDAMQAKWRPVWEKLDPFKARDDGSAERRYALTMFSYPSG-DLHMGHGEVFALHDVLA  75
            YD  A+++KW++ W   + FK+  D+S  + YAL MF+YPSG +LH+GH E ++  D+L+
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  76   RFWFQQGYDVMNPIGWDSFGLPAENAAIKRNEHPATYTYANIETQAESIRRYALSFDWSR  135
            RF   QG +V++P+GWD+FGLPAE+ A+   ++PA +T  NI      I   ++S+DW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  136  RLHTSDPEYYRWTQWLFLRFFERGLAYRKASYVNWCPNDQTVLANEQVV-QGRCERCGFE  194
             ++T+DP+YY+WTQW+F +++E+GLAY     VNW  +  T +ANE+V+ +G  ER G+ 
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  195  VTKRELTQWYFKTTEYAQRLLDDMSLLEWPEEILLMQRNWIGRSEGAFASFQVEGRDEPI  254
            V ++ + QW +K T YA+RLL+D+  ++WPE I  MQRNWIG+S GA  +F+V + D  +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  255  KVFTTRPDTLFGATFMVVAPDSKLAEELVTPDQRAAFDEYLKAVKATTEIERLSTERDKT  314
             VFTTRPDTLFGAT+ V+AP+  L + + T+DQ  A  +Y +     +++ R    ++KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  315  GVFLGSYATNPVTGERIPIWAADYVLADYGTGAIMAVPAQDSRDWEFAEKFGLPIVRTVQ  374
            GV  GSYA NPV G  +P+W ADYVLA YGTGAIMAVPA+D RDWEFA +F L I+  ++
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  375  PEEGFDGKAYTGDGPAINSANDEVDLNGLPVAEAKARIIDWLQDKGLGERTINYRLRDWL  434
              +  +  A+T DG  INS      L+GL  A A A++++WL+  G+G+  + YRLRDWL
Sbjct  364  GGNV-EEAAFTEDGLHINSDF----LDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWL  418

Query  435  LSRQRYWGAPIPIIHCPSCGEVPVPDDQLPVELPDLRGAALAPRGVSPLASVRDWVEVAC  494
            +SRQRYWG PIPIIH       +VP+ +LP+ LP  ++   +  G SPLA+V DW+EV+ 
Sbjct  419  FSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTR  478

Query  495  PKCGGAAERDTDTMDTFVDSSWYFLRYCSPDYTEGAFDPEAVNRWMPAYQYVGGKEHAVL  554
               G  + R+T+TM    +SSWY+LRY  P+ TE   D E +++W+P   YVGG EHAVL
Sbjct  479  ED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVL  537

Query  555  HLLYARFFTKALHDMGLLNAVEPFTRLLNQGQVINEG-----------------------  591
            HLLYARF  K L D+G++ + EPF +L+NQG ++  +                       
Sbjct  538  HLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFH  597

Query  592  -----------KAMSKSLGNGVNLGDQLDEFGVDAIRLTMVFAGPPDDDIDWADLSPGGS  640
                         MSKSL N VN +D ++++G D++R+  +F GP D  I W++ +  GS
Sbjct  598  VETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGS  657

Query  641  LRFLQRAWRLSGSVEAPVGADPAAGDLALRKITHRTVADATELIESYRFNVMVARVMELV  700
             +FL+R  RL  + E    ++  +G  AL K+ + TV   TE ++  +FN  +A++M +V
Sbjct  658  RKFLDRVYRLITTKEI---TEENSG--ALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFV  712

Query  701  NATRKAIDSGPGAADPAVREAVETVAILLSLVAPYTAEDMWEQL-GHAPTVAKAGWPKVD  759
            NA+ K         D    +       L++  AP  +E++W+ L + + +++   WP  D
Sbjct  713  NAANK--------EDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYD  764

Query  760  PALLVEESVTCVVQIAGKVKERLEVAPDISEADLEQLALASEAVQKALDGRGVRKVIVRA  819
             + LVE+ V  VVQI GKVK +L VA D+S  +L+++ALA+E VQ  + G+++ KVI  +
Sbjct  765  ESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVP  824

Query  820  PKLVNIV  826
             KLVNIV
Sbjct  825  NKLVNIV  831

868) leuS in NC_008009


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  563 bits (2126),  Expect = 2e-161, Method: Compositional matrix adjust.
 Identities = 364/861 (43%), Positives = 535/861 (63%), Gaps = 87/861 (10%)

Query  20   YDPRAIEEKWTVQWANDPELYASEPDSAKKKFYVLEMLPYPSGA-LHMGHVRNYAIGDAL  78
            YD  AIE KW   WA++   + +  D++K KFY L+M+PYPSGA LH+GH   Y+  D L
Sbjct  4    YDHTAIEPKWQAFWADNHT-FKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDIL  62

Query  79   ARFMWMTGHNVLHPMGWDAFGLPAENAAIKNQRQPREWTLGNIEAMKKQMRRLGFAYDWS  138
            +RF +  GHNVLHPMGWDAFGLPAE+ A+    +P E T  NI   K+Q+  LGF+YDW 
Sbjct  63   SRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWD  122

Query  139  KEIATCLPDYYRWNQWFFIKFFEKNLAYKRKSKVNWCPECATVLANEQVVDGCCWRHETT  198
            +E+ T  P+YY+W QW+F K++EK LAY     VNW  E +T +ANE+V+ +    +   
Sbjct  123  REVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGY  182

Query  199  RVEQRELEQWFFRITDYADELLRDLDQLEGWPEKVKTMQRNWIGRSEGALVTFKLEQPSG  258
             V ++ + QW ++IT YA+ LL DL++++ WPE +K MQRNWIG+S GA VTFK+ +   
Sbjct  183  PVVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKD---  238

Query  259  PSGDSITVFTTRIDTIFGATSLQLAPEHPIVTDLIASNPDLLSAVEDLKQQQ--RTAKEK  316
             ++  +TVFTTR DT+FGAT   LAPEH++V  + +S+     AV D K+Q   ++   +
Sbjct  239  -TDKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQA--EAVADYKRQASLKSDLAR  295

Query  317  GDIGAIEKHGVFTGAYAINPFNEEKVPIWIANYILTDYGTGAIMSVPAHDERDYEFATKY  376
             D++  EK GV TG+YAINP N   +P+WIA+Y+L+ YGTGAIM+VPAHDERD EFA ++
Sbjct  296  TDLAK-EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQF  354

Query  377  GLEVRVVILPRRVGEPPEAGKPETNVLPYSGTDSLLINSGDFTGLPVQEALEKMAKFAEE  436
             L++  V+         E+G+ E   +     D+L INS+ + GL    A+ KM    E 
Sbjct  355  NLDIIPVL---------EGGNVEEAAFT---EDGLHINSDFLDGLDKASAIAKMVEWLEA  402

Query  437  HGFGKATVTFRLKDWGISRQRYWGTPIPMLYCGKCGIVPVPEDQLPVLLPENVEI--TLA  494
            +G G+  VT+RL+DW +SRQRYWG PIP++        +VPE +LP++LP   +I  + +
Sbjct  403  EGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGT  462

Query  495  GGSPLTRVQEWLHTTCPKCGGPATRDTDTMDTFVDSSWYFYRYTNPQLTTAPVDTKTIDY  554
            G SPL+ V +WL+ T    G  + R+T+TM    +SSWY+ RY +P+ T    D   +  
Sbjct  463  GESPLANVTDWLEVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQ  521

Query  555  WFPIDQYIGGVEHAILHLIYSRFWTKVMRDLGLVHNSEPVTRLFTQGMVI----------  604
            W+P+D Y+GG EHA+LHL+Y+RFW KV+ DLG+V   EP  +LF QGM++          
Sbjct  522  WLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGA  581

Query  605  ---------KDG---------------AKMSKNLGNVVAPDDMIAKYGADATRMYTLFAA  640
                     +DG               AKMSK+L NVV PDD++ +YGAD+ R+Y +F +
Sbjct  582  LVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMG  641

Query  641  PPDRDLDWQDAGVEGVSRFLARVYRLIAQNPIVHAGPAHYTLAELPANAKKIARKLHQTI  700
            P D  + W + G+EG  +FL RVYRLI+ + I +  ++             + +  ++T+
Sbjct  642  PLDASIAWSEEGLEGSRKFLDRVYRLITTKEITEENSG------------ALDKVYNETV  689

Query  701  KRISDELGGRWHFNTCVAALMEFVNECYAAPELFANPKEGIERTLVADVQRKVTLLLQPF  760
            K ++++++    FNT +A LM FVN       LF++   G+ +            L+ PF
Sbjct  690  KAVTEQVDQM-KFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQ------------LIAPF  736

Query  761  APYVAHELWAMLGEPSGLLR-APWPAFDASLAKEDEVEIVVQVNGKVRSKLVVSTDASED  819
            AP +++ELW  L  ++  +   PWP++D S   E++VEIVVQ++GKV++KLVV+ D S +
Sbjct  737  APHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSRE  796

Query  820  EVKKLALADEKVQAAIAGKEI  840
            E++ +ALA+EKVQA IAGK+I
Sbjct  797  ELQEVALANEKVQAEIAGKDI  817

869) B565_0903 in NC_015424


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  562 bits (2123),  Expect = 3e-161, Method: Compositional matrix adjust.
 Identities = 366/865 (43%), Positives = 565/865 (66%), Gaps = 46/865 (5%)

Query  5    YVPQSIEPAVQKHWDAKKTFKAVEKVDKEKFYCLSMFPYPSGR-LHMGHVRNYTIGDVIS  63
            Y   +IEP  Q  W  + TFK+     K KFY L MFPYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRLNGKNVLQPIGWDAFGLPAENAAIKNNTAPAPWTYENIEYMKNQLKMLGLGYDWDR  123
            R++R +G NVL+P+GWDAFGLPAE+ A+     PA  T ENI   K Q++ LG++YDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EIATCKPDYYRWEQWFFTKLYEKGLVYKKTSSVNWCPNDMTVLANEQVV-DNCCWRCDTP  182
            E+ T  P+YY+W QW+FTKLYEKGL Y    +VNW  +  T +ANE+V+ D    R + P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VEQKEIPQWFIKITDYAEELLSDIDNLEGWPEMVKTMQRNWIGRSEGVNISFTIEGQAEQ  242
            V +K + QW +KIT YAE LL D+++++ WPE +K MQRNWIG+S G N++F + +   +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LEVYTTRPDTFMGVTYVGIAAGHPL--ALQAAQNNPELAAFI-EECKNTKVAEAELATME  299
            + V+TTRPDT+ G TY  +A+ H+L  A+ ++++   +A +  +   ++ +A ++LA  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGMATGLYAIHPLDGRKVPVWVANFVLMNYGTGAVMAVPAHDQRDFEFATKYGLDIKAV  359
            K G+ TG YAI+P++G+ +PVW+A++VL +YGTGA+MAVPAHD+RD EFA ++ LDI +V
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  360  IKPVEGDVDVSEAAYTEKGVLFNSGEFDGLDFQGAFDAIASKLEGLGKGKRTVNYRLRDW  419
            +     + +V EAA+TE G+ +NS+ +DGLD  +A+  +   LE+ G G+  V YRLRDW
Sbjct  362  L----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDW  417

Query  420  GVSRQRYWGAPIPMLTLADGTVVPTPEDQLPVLLP--EDVVMDGI-QSPIKADAEWAKTT  476
              SRQRYWG PIP++   DGT  + PE +LP++LP   D+   G  +SP+   ++W   T
Sbjct  418  LFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT  477

Query  477  Y-NGQEAFRETDTFDTFMESSWYYARYCSPDYDKGMLDPAAANHWLPVDQYIGGIEHACM  535
              +G  + RET+T      SSWYY RY  P+    + D    ++WLPVD Y+GG EHA +
Sbjct  478  REDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVL  537

Query  536  HLLYARFFHKLLRDAGLVNSDEPFKRLLCQGMVLADAFYYKDEKGGNVWVSPTDVKVERD  595
            HLLYARF HK+L D G+V + EPF++L+ QGM+L+ +  Y+D +G+ V    +  KVE+ 
Sbjct  538  HLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS--YRDSRGALV----ATDKVEK-  590

Query  596  EKGRITKAIDNEGREVMHSGMTKMSKSKNNGIDPQLMVERYGADTVRLFMMFASPAEMTL  655
               R    ++ E  E ++ + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P + ++
Sbjct  591  ---RDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASI  647

Query  656  EWSDSGVEGAQRFLRRLWR-VTFEHVSGGSVAALDVAALTNEQKAVRRELHKTIAKVSDD  714
             WS+ G+EG+++FL R+ R +T  +++  + +ALD            +  + T+  V+++
Sbjct  648  AWSEEGLEGSRKFLDRVYRLITTKEITEENSGALD------------KVYNETVKAVTEQ  695

Query  715  VGRRQTFNTAIAAIMELMNNLAKLGNDEQDRALMQEALEAVVVMLYPITPHIGFELWKML  774
            V++ + FNTAIA +M ++N   K      +  L  +   + V ++ P++PH+G ELW+ L
Sbjct  696  VDQMK-FNTAIAQLMVFVNAANK------EDKLFSDYAKGFVQLIAPFAPHLGEELWQAL  748

Query  775  -GKGDDIDHAAWPVADEAAMVETEKLVVVQINGKMRGKLTVPAEISQADVEKLAMADASV  833
             + G+ I   +WP  DE+ +VE +  +VVQI+GK+++KL V+ ++S+ +++ +A+A+  V
Sbjct  749  TASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKV  808

Query  834  QKFTDGLTVRKVIYVPGKLLNIVAN  858
            Q    G  + KVI VP KL+NIV +
Sbjct  809  QAEIAGKDIIKVIAVPNKLVNIVIK  833

870) WQG_15580 in NC_020515


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  562 bits (2123),  Expect = 3e-161, Method: Compositional matrix adjust.
 Identities = 364/866 (43%), Positives = 571/866 (66%), Gaps = 46/866 (5%)

Query  5    YNPSAIEPKVQQFWAENKVFKAIKDTSKPKYYCLSMFPYPSGR-LHMGHVRNYTIGDVVS  63
            Y+ +AIEPK Q FWA+N  FK+  D+SKPK+Y L MFPYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMNGKNVLQPMGWDAFGLPAEGAAIKNKTAPAKWTYENIEYMKNQLKILGFGFDWDR  123
            R++R +G NVL+PMGWDAFGLPAE  A+     PA  T ENI   K Q++ LGF++DWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVTTCRPEYYKWEQWFFTELYKKGLVYRKTSTVNWCPNDETVLANEQV-HEGCCWRCDTP  182
            EV T  P+YYKW QW+FT LY KGL Y     VNW  +  T +ANE+V  +G   R + P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VEQREIPQWFIKITDYAEQLLGGLDQLPNWPDQVKTMQRNWIGRSEGVEITFQIKDSDQT  242
            V ++ + QW +KIT YAE+LL +L+++ +WP+ +K MQRNWIG+S G ++TF++KD+D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LPVYTTRPDTFYGVSYVAVAAAHPLAEQ--AAKNNEKLAEFIREAK-NTKVAEADIATME  299
            + V+TTRPDT++G +Y  +A+ H+L +   ++ + E +A++ R+A  ++ +A +D+A  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGMATGLYAIHPLTGKEVPIWVANFVLMHYGTGAVMAVPAHDQRDFEFAQKYDLPINQV  359
            K G+ TG YAI+P+ GKE+P+W+A++VL  YGTGA+MAVPAHD+RD EFA++++L   ++
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNL---DI  358

Query  360  IAPLDGSEWDFGTAAYTEHGKLINSAEFDGNTFEQAFNGIADKLEALGVGKRQVNYRLRD  419
            I+ L+G+  +   AA+TE+G  INS  +DG     A+  + + LEA GVG+ +V YRLRD
Sbjct  359  IPVLEGG--NVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMLTLDSGEVVPAPMQDLPIILP--EDVVMDGV-KSPIKADPEWAKT  476
            W  SRQRYWG PIP++  + G   + P  +LP++LP   D+   G   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  TY-NGKSALKETDTFDTFMESSWYYARYTSPQFAEGMLDSDEANYWLPVDQYIGGIEHAT  535
            T  +G  + +ET+T      SSWYY RY  P+ +E + D +  + WLPVD Y+GG EHA 
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLLYFRFFHKLLRDAGLVNSDEPAEKLLCQGMVLADAFYYTSPTNERIWVSPTEVTLEK  595
            +HLLY RF HK+L D G+V + EP +KL+ QGM+L+ ++      + R     + V+ +K
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSR----GALVATDK  587

Query  596  DDKGRILKAFDKEGRELVHSGMTKMSKSKNNGIDPQEMVEKYGADTVRLFMMFASPAEMT  655
             +K R    F+ E  E ++ + +KMSKS +N ++P+++VE+YGADT+R++ MF +P + +
Sbjct  588  VEK-RDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  656  LEWQESGVEGAKRFLGRLWNLAYEYNQNPASVELDVSALTKAQKELRREVHKTIAKVSDD  715
            + W E G+EG+++FL+R+    Y         E + +AL K  +E       T+  V+++
Sbjct  647  IAWSEEGLEGSRKFLDRV----YRLITTKEITEENSGALDKVYNE-------TVKAVTEQ  695

Query  716  IGRRQTFNTAIAAIMELMNKLTKAELAGDQDKAVMKEALSAVIRMLYPITPHICFELWND  775
            +++ + FNTAIA +M ++N       A++++  +  +   + ++++ P++PH+  ELW+ 
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  776  LGFEG-TIDFAEWVQADESAMVEDEKLIVVQVNGKVRGKVTVPATATQEEIKAAALADEN  834
            L   G +I +  W   DES +VE++  IVVQ++GKV++K+ V+   ++EE++  ALA+E+
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  835  VQKFLENMEVVKEIYVPLKMFSFAVK  860
            VQ  +   +++K I VP K+ ++ +K
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVIK  833

871) leuS in NC_004347


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  562 bits (2122),  Expect = 4e-161, Method: Compositional matrix adjust.
 Identities = 368/868 (43%), Positives = 569/868 (66%), Gaps = 51/868 (5%)

Query  5    YNPSEIEALVQKHWHDTKTFEVTEDQNKEKFYCLSMFPYPSGR-LHMGHVRNYTIGDVVA  63
            Y+ + IE+  Q  W D  TF    D +K KFY L MFPYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RFQRLQGKNVLQPIGWDSFGLPAENAAINNKTAPAPWTYQNIEYMKNQLKLLGFGYDWSR  123
            RF+R QG NVL+P+GWD+FGLPAE+ A++    PA  T +NI   K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EIATCTPEYYRWEQWFFTKLYEKGLVYKKTASVNWCPNDETVLANEQV-QDGCCWRCDTP  182
            E+ T  P+YY+W QW+FTKLYEKGL Y    +VNW  +  T +ANE+V  DG   R + P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VEQKEIPQWFIKITAYAEELLNDIDTLDGWPEQVKTMQRNWIGRSEGVEMTFGVAGSDKS  242
            V +K + QW +KITAYAE LL+D++ +D WPE +K MQRNWIG+S G ++TF V ++DK 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  FDIYTTRPDTLMGVTYVAIAAGHPLAEIAAQTNPELAAFIDECKNSTTSEAELA----TM  298
            F ++TTRPDTL G TY  +A+ H+L  + A T ++ A  + + K  ++  ++LA    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHAL--VDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  299  EKRGVATGLYAIHPITGKQVPIWAANFVLMNYGTGAVMSVPGHDQRDYEFAKKYHLPIEA  358
            EK GV TG YAI+P+ GK++P+W A++VL +YGTGA+M+VP+HD+RD EFAK+++L I +
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VIKPAEGDLDISEAAYTEKGILFNSGEFDGLDFDGAFNVIANKLVAEGKGKRQVNYRLRD  418
            V+  +    ++ EAA+TE G+ +NS+ +DGLD  +A+  + + L AEG G+ +V YRLRD
Sbjct  361  VLEGG----NVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  419  WGVSRQRYWGAPIPMVTLADGTVIPTPEDQLPVILP--EDVVMDGI-QSPIKADKEWAK-  474
            W  SRQRYWG PIP++   DGT  + PE +LP++LP   D+   G  +SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  475  TQVNGQDALRETDTFDTFMESSWYYARYCSPQAEQML-DPTKANYWLPVDQYIGGIEHAC  533
            T+ +G  + RET+T      SSWYY RY  P+  + L D    + WLPVD Y+GG EHA 
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  534  MHLLYFRFFHKLLRDAGLVNTNEPAKQLLTQGMVLADAFYYTNDKGARVWVSPLDVATTE  593
            +HLLY RF HK+L D G+V T+EP ++L+ QGM+L+ +  Y + +GA        + +T+
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS--YRDSRGA--------LVATD  586

Query  594  KDDKGRITKAIDKDGNELVYTGMCKMSKSKNNGIDPQVMVEKYGADTVRLFMMFASPPEL  653
            K +K R    ++ +  E +  +  KMSKS +N ++P+ +VE+YGADT+R++ MF +P + 
Sbjct  587  KVEK-RDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  654  TLEWQESGVEGAHRFIKRLWKL-ASEYVAQDNSEALDVSKLTSEQKALRREVHKTIAKVT  712
            ++ W E G+EG+++F+ R+ +L ++  ++++NS ALD            +  + T+  VT
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALD------------KVYNETVKAVT  693

Query  713  DDIGRRQMFNTAVAAVMELMNHLQKAPQTTGQDRAIIGEALSAVVRLLYPIIPHVSFTLW  772
            +++++ + FNTA+A +M ++N       ++ ++  ++++   + V+L+ P+ PH++  LW
Sbjct  694  EQVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELW  745

Query  773  NEL-GNTNSIEDSQWPVVDESALVEDSKLIVVQVNGKVRAKITVAADADQASVEALGMAD  831
            + L ++ +SI    WP  DES LVE+   IVVQ++GKV+AK+ VA D  +  ++ +++A+
Sbjct  746  QALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALAN  805

Query  832  EQVIKYLDGVTVRKVIYVPGKLLSIVAN  859
            E+V   + G  + KVI VP KL++IV +
Sbjct  806  EKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

872) leuS in NC_008750


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  562 bits (2122),  Expect = 4e-161, Method: Compositional matrix adjust.
 Identities = 371/868 (43%), Positives = 566/868 (66%), Gaps = 51/868 (5%)

Query  5    YNPSEIEALVQKHWHDNKTFEVTEDANKEKFYCLSMFPYPSGR-LHMGHVRNYTIGDVVA  63
            Y+ + IE+  Q  W DN TF    DA+K KFY L MFPYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RFQRLQGKNVLQPIGWDSFGLPAENAAINNKTAPAPWTYENIEYMKNQLKLLGFGYDWSR  123
            RF+R QG NVL+P+GWD+FGLPAE+ A++    PA  T ENI   K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EIATCTPEYYRWEQWFFTKLYEKGLVYKKTASVNWCPNDETVLANEQV-QDGCCWRCDTP  182
            E+ T  P+YY+W QW+FTKLYEKGL Y    +VNW  +  T +ANE+V  DG   R + P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VEQKEIPQWFIKITAYAEELLNDIDTLDGWPEQVKTMQRNWIGRSEGVEMTFGVAGHDKT  242
            V +K + QW +KITAYAE LL+D++ +D WPE +K MQRNWIG+S G ++TF V + DK 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  FDIYTTRPDTLMGVTYVAIAAGHPLAEIAAQTNPELAAFIDECKNSTTSEAELA----TM  298
            F ++TTRPDTL G TY  +A+ H+L  + A T ++ A  + + K  ++  ++LA    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHAL--VDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  299  EKRGVATGLFAIHPITGKQVPIWAANFVLMNYGTGAVMSVPGHDQRDFEFAKKYGLAIEA  358
            EK GV TG +AI+P+ GK++P+W A++VL +YGTGA+M+VP+HD+RD EFAK++ L I +
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VIKPVDGEVDISEAAYTEKGILFNSGEFDGLDFDAAFNAIANKLVAEGKGKRQVNYRLRD  418
            V+       ++ EAA+TE G+ +NS+ +DGLD  +A+  + + L AEG G+ +V YRLRD
Sbjct  361  VL----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  419  WGVSRQRYWGAPIPMVTLADGTVIPTPEDQLPVLLP--EDVVMDGI-QSPIKADKEWAK-  474
            W  SRQRYWG PIP++   DGT  + PE +LP++LP   D+   G  +SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  475  TQVNGQDALRETDTFDTFMESSWYYARYCSPQADEML-DPAKANYWLPVDQYIGGIEHAC  533
            T+ +G  + RET+T      SSWYY RY  P+  E L D    + WLPVD Y+GG EHA 
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  534  MHLLYFRFFHKLLRDAGLVNSNEPAKQLLTQGMVLADAFYYINEKGARVWVSPLDVATTE  593
            +HLLY RF HK+L D G+V ++EP ++L+ QGM+L+ +  Y + +GA        + +T+
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS--YRDSRGA--------LVATD  586

Query  594  KDDKGRITKAIDKDGNELVYTGMCKMSKSKNNGIDPQVMVEKYGADTVRLFMMFASPPEL  653
            K +K R    ++ +  E +  +  KMSKS +N ++P+ +VE+YGADT+R++ MF +P + 
Sbjct  587  KVEK-RDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  654  TLEWQESGVEGAHRFIKRLWKL-ASEYIAQDNSEALDVSKLTSEQKALRREVHKTIAKVT  712
            ++ W E G+EG+++F+ R+ +L ++  I+++NS ALD            +  + T+  VT
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALD------------KVYNETVKAVT  693

Query  713  DDIGRRQMFNTAVAAVMELMNHLQKAPQTTGQDRAIIGEALSAVVRLLYPIIPHVSFTLW  772
            +++++ + FNTA+A +M ++N       ++ ++  ++++   + V+L+ P+ PH++  LW
Sbjct  694  EQVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELW  745

Query  773  NDLGNTG-SIEDSQWPVVDESALVEDSKLIVVQVNGKVRAKITVAADADKDSVEALGMND  831
            + L  +G SI    WP  DES LVE+   IVVQ++GKV+AK+ VA D  ++ ++ +++ +
Sbjct  746  QALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALAN  805

Query  832  EHVIKYLDGLTVRKVIYVPGKLLSIVAN  859
            E V   + G  + KVI VP KL++IV +
Sbjct  806  EKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

873) VVMO6_02307 in NC_014965


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  562 bits (2120),  Expect = 5e-161, Method: Compositional matrix adjust.
 Identities = 375/867 (44%), Positives = 569/867 (66%), Gaps = 51/867 (5%)

Query  5    YNPQDIEQKVQQHWDNNKTFVVTEDPTKEKFYCLSMFPYPSGR-LHMGHVRNYTIGDVVS  63
            Y+   IE K Q  W +N TF    D++K KFY L MFPYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RFQRLQGKNVMQPIGWDAFGLPAENAAVKNNTAPAPWTYENIEYMKNQLKLLGFGYDWNR  123
            RF+R QG NV++P+GWDAFGLPAE+ A+     PA  T ENI   K Q++ LGF+YDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EFATCTPEYYRWEQEFFTKLYEKGLVYKKTSSVNWCPNDQTVLANEQV-EDGCCWRCDTP  182
            E  T  P+YY+W Q +FTKLYEKGL Y    +VNW  +  T +ANE+V  DG   R + P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VEQKEIPQWFIKITEYAQELLDDLDKLEGWPEMVKTMQRNWIGRSEGVELKFEVKG-QQD  241
            V +K + QW +KIT YA+ LL+DL+ ++ WPE +K MQRNWIG+S G ++ F VK+ ++D
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  242  LEVYTTRPDTLMGVTYVGIAAGHPLAKIAAENNPELAAFIEECKNTKVAEAELA----TM  297
            + V+TTRPDTL G TY  +A+ H+L  + A   ++ A  + + K      ++LA    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHAL--VDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  298  EKKGMATGLTAIHPLNGREVPVYVANFVLMDYGTGAVMAVPAHDQRDFEFATKYGLDIIP  357
            EK G+ TG  AI+P+NG+E+PV +A++VL  YGTGA+MAVPAHD+RD EFA ++ LDIIP
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  358  VIKPIDGSELDISEAAYTEKGVLFDSGEFDGLEFQAAFDAIAAKLEAEGKGTKTVNFRLR  417
            V   ++G++++  EAA+TE G+ ++S+ +DGL+  +A+  +   LEAEG G   V +RLR
Sbjct  361  V---LEGGNVE--EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  418  DWGVSRQRYWGAPIPMVTTEDGQVHPVPADQLPVILP--EDVVMDGVT-SPIKADKEWAK  474
            DW  SRQRYWG PIP++  EDG   +VP  +LP++LP   D+   G   SP+    +W  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  475  TTF-NGEPALRETDTFDTFMESSWYYARYCSPQADDIL-DPEKANYWLPVDQYIGGIEHA  532
             T  +G  + RET+T      SSWYY RY  P+  + L D E  + WLPVD Y+GG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  533  CMHLLYSRFFHKLLRDAGYVTSDEPFKQLLCQGMVLADAFYYTNDKGGKEWVSPTEVKVE  592
             +HLLY+RF HK+L D G V + EPF++L+ QGM+L+ +  Y + +G+   + +T+ KVE
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS--YRDSRGA---LVATD-KVE  589

Query  593  RDGKGRITSAVDNEGRNVEHSGMIKMSKSKNNGIDPQEMVDKYGADTVRLFMMFASPADM  652
            + + + +     + G ++E++   KMSKS +N ++P+++V++YGADT+R++ MF +P D 
Sbjct  590  KRDGSFFHV---ETGEELEQAP-AKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  653  TLEWQESGVEGANRFLKRVWKLVNEHTSKGAAEAVNAAALSGDQKALRRDVHKTIAKVTD  712
            ++ W E G+EG+ +FL RV +L+   T+K  +E  ++        AL +  + T+  VT+
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLI---TTKEITEENSG--------ALDKVYNETVKAVTE  694

Query  713  DVARRQTFNTAIAAVMELMNKLAKAPQESAQDRAILDEALKAVVAMLYPITPHICFEMWT  772
            +V + + FNTAIA +M ++N        + ++  ++ +  K+ V ++ P++PH+  E+W 
Sbjct  695  QVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  773  AL--GQQDIDNASWPTYDEQALVEDEKLIVVQVNGKVRGKITVAADATKEQVEEIGLNEE  830
            AL  + + I   +WP+YDE  LVE++  IVVQ++GKV++K+ VA D ++E+++E++L +E
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  831  NVSKHLDGVTIRKVIYVPGKLLSIVAN  857
            +V  ++ G  I KVI VP KL++IV +
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVIK  833

874) leuS in NC_004459


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  561 bits (2119),  Expect = 6e-161, Method: Compositional matrix adjust.
 Identities = 375/867 (44%), Positives = 568/867 (66%), Gaps = 51/867 (5%)

Query  5    YNPQDIEQKVQQHWDNNKTFVVTEDPTKEKFYCLSMFPYPSGR-LHMGHVRNYTIGDVVS  63
            Y+   IE K Q  W +N TF    D++K KFY L MFPYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RFQRLQGKNVMQPIGWDAFGLPAENAAVKNNTAPAPWTYENIEYMKNQLKLLGFGYDWNR  123
            RF+R QG NV++P+GWDAFGLPAE+ A+     PA  T ENI   K Q++ LGF+YDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EFATCTPEYYRWEQEFFTKLYEKGLVYKKTSSVNWCPNDQTVLANEQV-EDGCCWRCDTP  182
            E  T  P+YY+W Q +FTKLYEKGL Y    +VNW  +  T +ANE+V  DG   R + P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VEQKEIPQWFIKITEYAQELLDDLDKLEGWPEMVKTMQRNWIGRSEGVELKFEVKG-QQD  241
            V +K + QW +KIT YA+ LL+DL+ ++ WPE +K MQRNWIG+S G ++ F VK+ ++D
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  242  LEVYTTRPDTLMGVTYVGIAAGHPLAKIAAENNPELAAFIEECKNTKVAEAELA----TM  297
            + V+TTRPDTL G TY  +A+ H+L  + A   ++ A  + + K      ++LA    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHAL--VDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  298  EKKGMATGLTAIHPLNGREVPVYVANFVLMDYGTGAVMAVPAHDQRDFEFATKYGLDIIP  357
            EK G+ TG  AI+P+NG+E+PV +A++VL  YGTGA+MAVPAHD+RD EFA ++ LDIIP
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  358  VIKPIDGSELDISEAAYTEKGVLFDSGEFDGLEFQAAFDAIAAKLEAEGKGTKTVNFRLR  417
            V   ++G++++  EAA+TE G+ ++S+ +DGL+  +A+  +   LEAEG G   V +RLR
Sbjct  361  V---LEGGNVE--EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  418  DWGVSRQRYWGAPIPMVTTEDGQVHPVPADQLPVILP--EDVVMDGVT-SPIKADKEWAK  474
            DW  SRQRYWG PIP++  EDG   +VP  +LP++LP   D+   G   SP+    +W  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  475  TTF-NGEPALRETDTFDTFMESSWYYARYCSPQADDIL-DPEKANYWLPVDQYIGGIEHA  532
             T  +G  + RET+T      SSWYY RY  P+  + L D E  + WLPVD Y+GG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  533  CMHLLYSRFFHKLLRDAGYVTSDEPFKQLLCQGMVLADAFYYTNDKGGKEWVSPTEVKVE  592
             +HLLY+RF HK+L D G V + EPF++L+ QGM+L+ +  Y + +G+   + +T+ KVE
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS--YRDSRGA---LVATD-KVE  589

Query  593  RDGKGRITSAVDNEGRNVEHSGMIKMSKSKNNGIDPQEMVDKYGADTVRLFMMFASPADM  652
            + + + +     + G ++E++   KMSKS +N ++P+++V++YGADT+R++ MF +P D 
Sbjct  590  KRDGSFFHV---ETGEELEQAP-AKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  653  TLEWQESGVEGANRFLKRVWKLVNEHTSKGAAEAVDAAALSGDQKALRRDVHKTIAKVTD  712
            ++ W E G+EG+ +FL RV +L+   T+K  +E         +  AL +  + T+  VT+
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLI---TTKEITEE--------NSGALDKVYNETVKAVTE  694

Query  713  DVARRQTFNTAIAAVMELMNKLAKAPQESAQDRAILDEALKAVVAMLYPITPHICFEMWT  772
            +V + + FNTAIA +M ++N        + ++  ++ +  K+ V ++ P++PH+  E+W 
Sbjct  695  QVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  773  AL--GQQDIDNASWPTYDEQALVEDEKLIVVQVNGKVRGKITVAADATKEQVEEIGLNEE  830
            AL  + + I   +WP+YDE  LVE++  IVVQ++GKV++K+ VA D ++E+++E++L +E
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  831  NVSKHLDGVTIRKVIYVPGKLLSIVAN  857
            +V  ++ G  I KVI VP KL++IV +
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVIK  833

875) leuS in NC_005139


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  561 bits (2119),  Expect = 6e-161, Method: Compositional matrix adjust.
 Identities = 375/867 (44%), Positives = 569/867 (66%), Gaps = 51/867 (5%)

Query  5    YNPQDIEQKVQQHWDNNKTFVVTEDPTKEKFYCLSMFPYPSGR-LHMGHVRNYTIGDVVS  63
            Y+   IE K Q  W +N TF    D++K KFY L MFPYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RFQRLQGKNVMQPIGWDAFGLPAENAAVKNNTAPAPWTYENIEYMKNQLKLLGFGYDWNR  123
            RF+R QG NV++P+GWDAFGLPAE+ A+     PA  T ENI   K Q++ LGF+YDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EFATCTPEYYRWEQEFFTKLYQKGLVYKKTSSVNWCPNDQTVLANEQV-EDGCCWRCDTP  182
            E  T  P+YY+W Q +FTKLY+KGL Y    +VNW  +  T +ANE+V  DG   R + P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VEQKEIPQWFIKITEYAQELLDDLDTLEGWPEMVKTMQRNWIGRSEGVELKFEVKG-QQD  241
            V +K + QW +KIT YA+ LL+DL+ ++ WPE +K MQRNWIG+S G ++ F VK+ ++D
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  242  LEVYTTRPDTLMGVTYVGIAAGHPLAKIAAENNPDLAAFIEECKNTKVAEAELA----TM  297
            + V+TTRPDTL G TY  +A+ H+L  + A   +D A  + + K      ++LA    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHAL--VDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  298  EKKGMATGLTAIHPLNGREVPVYVANFVLMDYGTGAVMAVPAHDQRDFEFATKYGLDIIP  357
            EK G+ TG  AI+P+NG+E+PV +A++VL  YGTGA+MAVPAHD+RD EFA ++ LDIIP
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  358  VIKPIDGSELDISEAAYTEKGVLFDSGEFDGLEFQAAFDAIAAKLEAEGKGTKTVNFRLR  417
            V   ++G++++  EAA+TE G+ ++S+ +DGL+  +A+  +   LEAEG G   V +RLR
Sbjct  361  V---LEGGNVE--EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  418  DWGVSRQRYWGAPIPMVTTEDGQVHPVPADQLPVILP--EDVVMDGVT-SPIKADKEWAK  474
            DW  SRQRYWG PIP++  EDG   +VP  +LP++LP   D+   G   SP+    +W  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  475  TTF-NGEPALRETDTFDTFMESSWYYARYCSPQADDIL-DPEKANYWLPVDQYIGGIEHA  532
             T  +G  + RET+T      SSWYY RY  P+  + L D E  + WLPVD Y+GG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  533  CMHLLYSRFFHKLLRDAGYVTSDEPFKQLLCQGMVLADAFYYTNDKGGKEWVSPTEVKVE  592
             +HLLY+RF HK+L D G V + EPF++L+ QGM+L+ +  Y + +G+   + +T+ KVE
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS--YRDSRGA---LVATD-KVE  589

Query  593  RDGKGRITSAVDNEGRNVEHSGMIKMSKSKNNGIDPQEMVDKYGADTVRLFMMFASPADM  652
            + + + +     + G ++E++   KMSKS +N ++P+++V++YGADT+R++ MF +P D 
Sbjct  590  KRDGSFFHV---ETGEELEQAP-AKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  653  TLEWQESGVEGANRFLKRVWKLVNEHTSKGAAEAVNAAALSGDQKALRRDVHKTIAKVTD  712
            ++ W E G+EG+ +FL RV +L+   T+K  +E  ++        AL +  + T+  VT+
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLI---TTKEITEENSG--------ALDKVYNETVKAVTE  694

Query  713  DVARRQTFNTAIAAVMELMNKLAKAPQESAQDRAILDEALKAVVAMLYPITPHICFEMWT  772
            +V + + FNTAIA +M ++N        + ++  ++ +  K+ V ++ P++PH+  E+W 
Sbjct  695  QVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  773  AL--GQQDIDNASWPTYDEQALVEDEKLIVVQVNGKVRGKITVAADATKEQVEEIGLNEE  830
            AL  + + I   +WP+YDE  LVE++  IVVQ++GKV++K+ VA D ++E+++E++L +E
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  831  NVSKHLDGVTIRKVIYVPGKLLSIVAN  857
            +V  ++ G  I KVI VP KL++IV +
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVIK  833

876) Sulac_2973 in NC_016884


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  561 bits (2118),  Expect = 7e-161, Method: Compositional matrix adjust.
 Identities = 349/844 (42%), Positives = 545/844 (65%), Gaps = 57/844 (6%)

Query  16   YDVKSVERFWQERWEKDALYRTRPD-DRQKFYCLEQFPYPSGH-LHMGHVRVYTLGDVIA  73
            YD  ++E  WQ  W  +  ++T  D  + KFY L+ FPYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  74   RYRRMRGYSVLHPMGWDAFGLPAENAAIKNGIPPKISTLNNIDYMRQQMRQMGLSFDWSR  133
            R++R +G +VLHPMGWDAFGLPAE+ A+  G  P   T +NI   ++Q+  +G+S+DW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  134  EVTTCLPDYYRFTQELFLLFYERGLAYQKAGAVNWCPSCETVLANEQV-EDGRCWRCDSV  192
            EV T  P+YY+ TQ +F  +YE+GLAY+   +VNW     T +ANE+V  DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  193  VTKRDLTQWYFRITEYADRLLEGLDRVDWPNEIKAQQIHWIGKSEGAEVHFPVQGLDDVI  252
            V ++ + QW ++IT YA+RLLE+L+ VDWP+ IK  Q +WIGKS GA+V F V++ D  +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  253  RVFTTRPDTLYGATYVVLAPEHPLVEKLVQNRPEQNQVREFVAAERVRSDIERTSETTEK  312
             VFTTRPDTL+GATY VLAPEH+LV+  +    + + V ++     ++SD+ RT  + EK
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDA-ITTSDQAEAVADYKRQASLKSDLARTDLAKEK  302

Query  313  RGVFTGAYALHPLTGEALPIWVANYVLVDYGTGAVMGVPAHDVRDYHYATKYELPIRPVI  372
             GV TG+YA++P+ G  +P+W+A+YVL  YGTGA+M+VPAHD RD ++A +++L I PV+
Sbjct  303  TGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL  362

Query  373  QPTDGQSADLPYVEPGVLINSGSFSGLASTEAKGAISRHLESIGRGKPRITYRMRDWLIS  432
            +  +G+  + ++ E G+ INS+ + GL  + A + +   LE+ G G+  +TYR+RDWL+S
Sbjct  363  E--GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  433  RQRYWGAPIPMIHCPHCGVVPVPKRDLPVLLP--ENVVFTGRGASPLAQVEDWVNTECPV  490
            RQRYWG PIP+IH  +    +VP  +LP++LP   ++  +G G SPLA+V DW++     
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  491  CHGPARRETDTMDTFVDSSWYYFRYTSPEAQDRPFDFEQANYWMPVDEYVGGKEHAVLHL  550
                +RRET+TM    +SSWYY+RY  P+  ++  D E  + W+PVD YVGG EHAVLHL
Sbjct  481  G-VKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHL  539

Query  551  LYSRFFTKVLYDAGWVAVDEPFKRLLAQGMVV---YQG----------------------  585
            LY+RF  KVLYD G V+  EPF++L+ QGM++   Y++                      
Sbjct  540  LYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVE  599

Query  586  ---------AKMSKSKGNTLSPEEILREWGTDATRLFMLFAAPPEKDFEWSQQGVEGTFR  636
                     AKMSKS  N ++P++++ + G+D+ R++ +F +P +  + WS++G+EG+ +
Sbjct  600  TGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRK  659

Query  637  FLQRVYRLVTRPFADARASSPEAEERVQRANARAIKKVTEDLGDRRAFNTAVSALMELTN  696
            FL+RVYRL+T     ++  + E    +++    ++K VTE++++ + FNTA++ LM    
Sbjct  660  FLDRVYRLIT-----TKEITEENSGALDKVYNETVKAVTEQVDQMK-FNTAIAQLM----  709

Query  697  ALYQDIEQVSPELRQHVLESLVLLLAPMAPHLAEELWHHL-GHTESVHLAAWPDYDPKWL  755
             ++ +  +    L  +   ++V L+AP APHL+EELW+ L +  ES+   +WP YD   L
Sbjct  710  -VFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKL  768

Query  756  EERQIEIALQVNGKVRGRMVITPDWDETRIREEAL--QYLQAQIEGRRVVKTIVIPTRLV  813
             E ++EI +Q++GKV++++V++ D     ++E AL  + +QA+I G+ ++K I +P +LV
Sbjct  769  VENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLV  828

Query  814  NVVV  817
            N+V+
Sbjct  829  NIVI  832

877) leuS in NC_015757


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  561 bits (2118),  Expect = 7e-161, Method: Compositional matrix adjust.
 Identities = 349/844 (42%), Positives = 545/844 (65%), Gaps = 57/844 (6%)

Query  6    YDVKSVERFWQERWEKDALYRTRPD-DRQKFYCLEQFPYPSGH-LHMGHVRVYTLGDVIA  63
            YD  ++E  WQ  W  +  ++T  D  + KFY L+ FPYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYRRMRGYSVLHPMGWDAFGLPAENAAIKNGIPPKISTLNNIDYMRQQMRQMGLSFDWSR  123
            R++R +G +VLHPMGWDAFGLPAE+ A+  G  P   T +NI   ++Q+  +G+S+DW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVTTCLPDYYRFTQELFLLFYERGLAYQKAGAVNWCPSCETVLANEQV-EDGRCWRCDSV  182
            EV T  P+YY+ TQ +F  +YE+GLAY+   +VNW     T +ANE+V  DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VTKRDLTQWYFRITEYADRLLEGLDRVDWPNEIKAQQIHWIGKSEGAEVHFPVQGLDDVI  242
            V ++ + QW ++IT YA+RLLE+L+ VDWP+ IK  Q +WIGKS GA+V F V++ D  +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  243  RVFTTRPDTLYGATYVVLAPEHPLVEKLVQNRPEQNQVREFVAAERVRSDIERTSETTEK  302
             VFTTRPDTL+GATY VLAPEH+LV+  +    + + V ++     ++SD+ RT  + EK
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDA-ITTSDQAEAVADYKRQASLKSDLARTDLAKEK  302

Query  303  RGVFTGAYALHPLTGEALPIWVANYVLVDYGTGAVMGVPAHDVRDYHYATKYELPIRPVI  362
             GV TG+YA++P+ G  +P+W+A+YVL  YGTGA+M+VPAHD RD ++A +++L I PV+
Sbjct  303  TGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL  362

Query  363  QPTDGQSADLPYVEPGVLINSGSFSGLASTEAKGAISRHLESIGRGKPRITYRMRDWLIS  422
            +  +G+  + ++ E G+ INS+ + GL  + A + +   LE+ G G+  +TYR+RDWL+S
Sbjct  363  E--GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  423  RQRYWGAPIPMIHCPHCGVVPVPKRDLPVLLP--ENVVFTGRGASPLAQVEDWVNTECPV  480
            RQRYWG PIP+IH  +    +VP  +LP++LP   ++  +G G SPLA+V DW++     
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  481  CHGPARRETDTMDTFVDSSWYYFRYTSPEAQDRPFDFEQANYWMPVDEYVGGKEHAVLHL  540
                +RRET+TM    +SSWYY+RY  P+  ++  D E  + W+PVD YVGG EHAVLHL
Sbjct  481  G-VKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHL  539

Query  541  LYSRFFTKVLYDAGWVAVDEPFKRLLAQGMVV---YQG----------------------  575
            LY+RF  KVLYD G V+  EPF++L+ QGM++   Y++                      
Sbjct  540  LYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVE  599

Query  576  ---------AKMSKSKGNTLSPEEILREWGTDATRLFMLFAAPPEKDFEWSQQGVEGTFR  626
                     AKMSKS  N ++P++++ + G+D+ R++ +F +P +  + WS++G+EG+ +
Sbjct  600  TGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRK  659

Query  627  FLQRVYRLVTRPFADARASSPEAEERVQRANARAIKKVTEDLGDRRAFNTAVSALMELTN  686
            FL+RVYRL+T     ++  + E    +++    ++K VTE++++ + FNTA++ LM    
Sbjct  660  FLDRVYRLIT-----TKEITEENSGALDKVYNETVKAVTEQVDQMK-FNTAIAQLM----  709

Query  687  ALYQDIEQVSPELRQHVLESLVLLLAPMAPHLAEELWHHL-GHTESVHLAAWPDYDPKWL  745
             ++ +  +    L  +   ++V L+AP APHL+EELW+ L +  ES+   +WP YD   L
Sbjct  710  -VFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKL  768

Query  746  EERQIEIALQVNGKVRGRMVITPDWDETRIREEAL--QYLQAQIEGRRVVKTIVIPTRLV  803
             E ++EI +Q++GKV++++V++ D     ++E AL  + +QA+I G+ ++K I +P +LV
Sbjct  769  VENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLV  828

Query  804  NVVV  807
            N+V+
Sbjct  829  NIVI  832

878) Sput200_3007 in NC_017566


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  561 bits (2118),  Expect = 8e-161, Method: Compositional matrix adjust.
 Identities = 369/868 (43%), Positives = 566/868 (66%), Gaps = 51/868 (5%)

Query  5    YNPSEIEALVQKHWHDNKTFEVTEDANKEKFYCLSMFPYPSGR-LHMGHVRNYTIGDVVA  63
            Y+ + IE+  Q  W DN TF    DA+K KFY L MFPYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RFQRLQGKNVLQPIGWDSFGLPAENAAINNKTAPAPWTYENIEYMKNQLKLLGFGYDWSR  123
            RF+R QG NVL+P+GWD+FGLPAE+ A++    PA  T ENI   K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EIATCTPEYYRWEQWFFTKLYEKGLVYKKTASVNWCPNDETVLANEQV-QDGCCWRCDTP  182
            E+ T  P+YY+W QW+FTKLYEKGL Y    +VNW  +  T +ANE+V  DG   R + P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VEQKEIPQWFIKITAYAEELLNDIDTLDGWPEQVKTMQRNWIGRSEGVEMTFGVAGHDKT  242
            V +K + QW +KITAYAE LL+D++ +D WPE +K MQRNWIG+S G ++TF V + DK 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  FDIYTTRPDTLMGVTYVAIAAGHPLAEIAAQTNPELAAFIDECKNSTTSEAELA----TM  298
            F ++TTRPDTL G TY  +A+ H+L  + A T ++ A  + + K  ++  ++LA    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHAL--VDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  299  EKRGVATGLFAIHPITGKQVPIWAANFVLMNYGTGAVMSVPGHDQRDFEFAKKYGLAIEA  358
            EK GV TG +AI+P+ GK++P+W A++VL +YGTGA+M+VP+HD+RD EFAK++ L I +
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VIKPVDGDVDISEAAYTEKGILFNSGEFDGLDFEAGFNAIANKLVAEGKGKRQVNYRLRD  418
            V+     + ++ EAA+TE G+ +NS+ +DGLD  +++  + + L AEG G+ +V YRLRD
Sbjct  361  VL----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  419  WGVSRQRYWGAPIPMVTLADGTVIPTPADQLPVLLP--EDVVMDGI-QSPIKADKEWAK-  474
            W  SRQRYWG PIP++   DGT  + P  +LP++LP   D+   G  +SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  475  TQVNGQDALRETDTFDTFMESSWYYARYCSPQADEML-DPAKANYWLPVDQYIGGIEHAC  533
            T+ +G  + RET+T      SSWYY RY  P+  E L D    + WLPVD Y+GG EHA 
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  534  MHLLYFRFFHKLLRDAGLVNSNEPAKQLLTQGMVLADAFYYINEKGARVWVSPLDVATTE  593
            +HLLY RF HK+L D G+V ++EP ++L+ QGM+L+ +  Y + +GA        + +T+
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS--YRDSRGA--------LVATD  586

Query  594  KDDKGRITKAIDKDGNELVYTGMCKMSKSKNNGIDPQVMVEKYGADTVRLFMMFASPPEL  653
            K +K R    ++ +  E +  +  KMSKS +N ++P+ +VE+YGADT+R++ MF +P + 
Sbjct  587  KVEK-RDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  654  TLEWQESGVEGAHRFIKRLWKL-ASEYIAQDNSEALDVSKLTSEQKALRREVHKTIAKVT  712
            ++ W E G+EG+++F+ R+ +L ++  I+++NS ALD            +  + T+  VT
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALD------------KVYNETVKAVT  693

Query  713  DDIGRRQMFNTAVAAVMELMNHLQKAPQTTGQDRAIIGEALSAVVRLLYPIIPHVSFTLW  772
            +++++ + FNTA+A +M ++N       ++ ++  ++++   + V+L+ P+ PH++  LW
Sbjct  694  EQVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELW  745

Query  773  NDLGNTG-SIEDSQWPVVDESALVEDSKLIVVQVNGKVRAKITVAADADKDSVEALGMND  831
            + L  +G SI    WP  DES LVE+   IVVQ++GKV+AK+ VA D  ++ ++ +++ +
Sbjct  746  QALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALAN  805

Query  832  EHVIKYLDGLTVRKVIYVPGKLLSIVAN  859
            E V   + G  + KVI VP KL++IV +
Sbjct  806  EKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

879) leuS in NC_016745


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  561 bits (2117),  Expect = 8e-161, Method: Compositional matrix adjust.
 Identities = 364/867 (42%), Positives = 563/867 (65%), Gaps = 49/867 (5%)

Query  5    YNPQNIEPQVQRHWDTQQTFKATEQPGKDKFYCLSMFPYPSGR-LHMGHVRNYTIGDVIS  63
            Y+   IEP+ Q  W  ++TFK+  +++K KFY L MFPYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRLQGKNVLQPIGWDAFGLPAENAAINNKTAPAPWTYENIDYMKNQLKRLGFGYDWDR  123
            R++R QG NVL+P+GWDAFGLPAE+ A++    PA  T ENI   K Q++ LGF+YDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCTPEYYRWEQWFFTKLYEKGLVYKKTSSVNWCPNDETVLANEQV-NDGCCWRCDTP  182
            E+ T  P+YY+W QW+FTKLYEKGL Y    +VNW  +  T +ANE+V  DG   R + P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VEQKEIPQWFIKITDYADELLRDIDELEGWPEQVKTMQRNWIGRSEGVTLRFDVAGADDG  242
            V +K + QW +KIT YA+ LL D++E++ WPE +K MQRNWIG+S G  + F V ++D +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  FEVYTTRPDTLFGVTYVGIAAGHplaakaaennpalaaFIDDCKHNKVAEADMA----TM  298
            F V+TTRPDTLFG TY  +A+ H+L    + ++ A A  + D K++    +D+A    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEA--VADYKRQASLKSDLARTDLAK  300

Query  299  EKKGMATGLMAVHPLTGKQVPIWVANFVLMDYGSGAVMAVPAHDQRDYEFATKYGLDIVP  358
            EK G+ TG  A++P+ GK++P+W+A++VL  YG+GA+MAVPAHD+RD EFA ++ LDI+P
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VIKPADGSELDVSQEAFTEKGLLFHSNEFDGMNFEQAFDAIARTLEEKGLGRRTVNFRLR  418
            V+  +     +V + AFTE GL ++S+ +DG++   A+  +   LE  G+G   V +RLR
Sbjct  361  VLEGG-----NVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  419  DWGVSRQRYWGAPIPMLNLEDGSVVGAPEESLPVVLP--EDVVMDGI-QSPIKADPEWAK  475
            DW  SRQRYWG PIP+++ EDG+  + PE  LP+VLP   D+   G  +SP+    +W  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  476  TTY-HGQPALRETDTFDTFMESSWYYARYCSPDYDQGMLDVEKANYWLPVDQYIGGIEHA  534
             T  +G  + RET+T      SSWYY RY  P+  + + D E  + WLPVD Y+GG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  535  CMHLLYARFFHKLLRDTGLVESDEPFKRLLCQGMVLADAFYHIDDKGGRTWVSPLDVTVE  594
             +HLLYARF HK+L D G+V + EPF++L+ QGM+L+ ++     +++R   ++L V+ +
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSR---GAL-VATD  586

Query  595  RDEKGRISKATDKDGRELVHTGMTKMSKSKNNGIDPQVMVDKYGADTVRLFMMFASPADM  654
            + EK R +   + +  E ++ + +KMSKS +N ++P+ +V++YGADT+R++ MF +P D 
Sbjct  587  KVEK-RDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  655  TLEWSDSGVEGAQRFLKRLWKLVFEHQSHGAAPALNLSGLSSEQKTLRRELHKTIAKVSD  714
            ++ WS+ G+EG+++FL R+ +L+   +     ++           +L +  + T+  V++
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLITTKEITEENSG-----------ALDKVYNETVKAVTE  694

Query  715  DVGRRQTFNTAIAAIMELMNHLAKVDMSDEQNRALLQEALEAVVVMLHPIVPHACFELWR  774
            +V++ + FNTAIA +M ++N   K D        L+ +   + V ++ P+ PH   ELW+
Sbjct  695  QVDQMK-FNTAIAQLMVFVNAANKEDK-------LFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  775  ALGHTD--IDHAAWPVVDAEALVEDEKLVVVQVNGKVRGKVTVPADASQDAVESAGKADD  832
            AL  ++  I   +WP  D   LVE++  +VVQ++GKV++K+ V+ D S++ ++  + A++
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  833  NVARHLDGKTIRKVIYVPGKLLNIVAN  859
            +V  ++ GK I KVI VP KL+NIV +
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVIK  833

880) Thexy_2006 in NC_015555


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  561 bits (2117),  Expect = 9e-161, Method: Compositional matrix adjust.
 Identities = 369/830 (45%), Positives = 530/830 (64%), Gaps = 57/830 (6%)

Query  6    DIDKKWQKKWEDTKLYKFNPENIDKKLYCLEMFSYPSGAKLHAGHWYNYGPADSWARMKR  65
             I+ KWQ  W D   +K   +    K+Y L+MF+YPSGA LH GH   Y ++D  +R KR
Sbjct  8    AIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSRFKR  67

Query  66   MQGYEVFHPMGFDAFGLPAENYAIKTGIHPQDSTLQNIKTMERQLREMGATFDWDYEVIT  125
             QG +V+HPMG DAFGLPAE+YA+ TG +P + T +NI    RQ+  +G ++DWD EV T
Sbjct  68   AQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDREVNT  127

Query  126  CLPDYYKWTQWVFLQLYKKGLAYRKKAPVNWCPSCKTVLANEQVV-EGTCERCGSEVTKK  184
              P+YYKWTQW+F +LY KGLAY    PVNW     T +ANE+V+ +GT ER G  V +K
Sbjct  128  TDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRK  187

Query  185  DLTQWFLKITDYAEELLNKLDELDWPEKTKMMQRNWIGKSDGAEIEFKVDGKDISFKVFT  244
             + QW LKIT YAE LL+ L+E+DWPE  K MQRNWIGKS GA++ FKV + D  F VFT
Sbjct  188  PMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFT  247

Query  245  TRADTLYGVTYVVLAPENEIVDLITTDEHRRNVEDYKEYARKQSEIERLSTEKEKTGVFT  304
            TR+DTL+G TY VLAPE+ +VD ITT ++   V DYK  A  +S++ R    KEKTGV T
Sbjct  248  TRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVWT  307

Query  305  GAYAIHPITSERVPIWISDYVLATYGTGCVMAVPAHDERDYSFAKKYDLPIKRVIKGKDG  364
            G+YAI+P+ +  +P+WI+DYVLA+YGTG +MAVPAHDERD  FAK+++L I  V+ G + 
Sbjct  308  GSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEG-GN  366

Query  365  VDDSLPFVEYGILVDSGDFTGSKSEDARIEIVKMLEKEGKGALKVNYRLRDWLVSRQRYW  424
            V+++ +F E G+ ++S+ + G     A   +V  LE EG G  +V YRLRDWL SRQRYW
Sbjct  367  VEEA-AFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYW  425

Query  425  GAPIPIIHCDKCGlvpvpeedlpvllpYNVEFSPD--GESPLKKSEEFMNTTCPKCGGKA  482
            G PIPIIH +     +VPE +LP++LP   ++ P   GESPL +  + ++ T    G K+
Sbjct  426  GEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED-GVKG  484

Query  483  LRDPDTLDTFVDSSWYFLRYPDNKNDKEPFNKELIDKMLPVDKYIGGAEHACMHLLYARF  542
             R+ +T+    +SSWY+LRY D  N     + EL+ + LPVD Y+GGAEHA +HLLYARF
Sbjct  485  RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARF  544

Query  543  VTKALRDLGYLDFDEPFKSLIHQGIILGP-------------------------------  571
              K L DLG +   EPF+ L++QG+ILG                                
Sbjct  545  WHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEEL  604

Query  572  --DGNKMSKSRGNTISPDEYINEYGSDVFRMYLMFGFAFTEGGPWNDDGIKAMSRFIQRI  629
                 KMSKS  N ++PD+ +++YG+D +R+Y MF  ++  + +W+++G+ +  +F++R+
Sbjct  605  EQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRV  664

Query  630  ERLVDKFIEEKGKAGKDEISKDEKELNYVRNYAIKSVTEDAEKFQFNTAIARIMELVNAL  689
             RL+         + K+    +   L+ V N ++K+VTE+ ++ +FNTAIA++M +VNA 
Sbjct  665  YRLI---------TTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNA-  714

Query  690  YKYDAEIEIKNTKLYEETIADLVRLLAPFAPHFAEEMWERLGYSYSVFN-QKWPEYDEKA  748
                     K+ KL+ +   ++V+L+APFAPH++EE+W+ L  S   ++   WP YDE  
Sbjct  715  -------ANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESK  767

Query  749  LVKDVVEIAIQVNGKVRGRLEVSPDASEKEIQDAAISAESIKQYIDGKEI  798
            LV + VEI +Q++GKV+++L V+ D S  E+Q+ A++ E ++  I GK+I
Sbjct  768  LVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDI  817

881) Flexsi_1305 in NC_015672


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  561 bits (2117),  Expect = 9e-161, Method: Compositional matrix adjust.
 Identities = 351/859 (41%), Positives = 551/859 (65%), Gaps = 38/859 (4%)

Query  3    YNHSEVESTWQKLWEEHKSYKTSKDESKEKFYCLEMFPYPSGK-IHMGHVRNYAIGDVVA  61
            Y+H+ +E+ WQ +W ++ ++KT+ D SK KFY L+MFPYPSG  +H+GH   Y+  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  62   RYKTMKGFNVIHPMGWDAFGLPAENAAIKNKIHPAKWTYSNIKFMKEQLKKLGLSYDWDR  121
            R+K  +G NV+HPMGWDAFGLPAE+ A+    +PA  T  NI   K Q++ LG+SYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  122  EIATCDPEYYKWEQLVFIKMFEKGLVYNKTSNVNWCEDCNTVLANEQV-EDGKCWRCGND  180
            E+ T DP+YYKW Q +F K++EKGL Y+    VNW E+  T +ANE+V  DG   R G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  181  VEIKELDGWFFKISEYADELLDYTYKMDGWPEKVLTMQRNWIGKSHGAIIRFPLQELDEP  240
            V  K +  W +KI+ YA+ LL+      +WPE +  MQRNWIGKS GA + F +++ D  
Sbjct  184  VVRKPMRQWMLKITAYAERLLE-DLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  241  IEVFTTRPDTLYGANFMLIAPEHPLTRQLIAGTEKEEEGIKFINSILKEEKISRMAEDKE  300
            + VFTTRPDTL+GA + ++APEH+L  + I+ +++ E    +         ++R    KE
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALV-DAITTSDQAEAVADYKRQASLKSDLARTDLAKE  301

Query  301  KKGFFTGKYVTNPMTNKQIPIYIANYVLMDYGTGAIMAVPAHDQRDFDFAKEYNLPITVV  360
            K G  TG Y  NP+  K++P+ IA+YVL  YGTGAIMAVPAHD+RD +FAK++NL I  V
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  361  IQPEGKELNGENMEEAYAGDGYLVNSGKFNGLDVETAKEKITEYLNENNLGEKTVNYRLK  420
            ++       G+  E A++ DG  +NS+ ++GLD  +A  K+ E L+ + +G+  V YRL+
Sbjct  362  LE------GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  421  DWGISRQRYWGAPIPVVHCEKCGVVPVKDEDLPVELPLDVEFTGIG---NPLESAEEFVN  477
            DW +SRQRYWG PIP++H E     +V + +LP+ LP+  ++   G   +PL +  + ++
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  478  TECPRCSAPAKRETDTMDTFVESSWYFLRYCSPQCETAPFNKDEANYWMPVDQYIGGVEH  537
                  +  ++RET+TM     SSWY+LRY  P+      + +  + W+PVD Y+GG EH
Sbjct  476  V-TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEH  534

Query  538  AIMHLLYARFYTKILRDLGFLNVDEPFQNLLTQGMVCKETYKCPIHGWLFPEEVENDKCV  597
            A++HLLYARF  K+L DLG +   EPFQ+L+ QGM+   +Y+ +  + +  + VE+    
Sbjct  535  AVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGS  594

Query  598  I--CDSDVEIGRV-EKMSKSKKNVVDPDNLIKEYGADTARLFSLFAAPPDRDLEWNQQGV  654
            +   +++ E+ +   KMSKS KNVV+PD+++ +YGADT R++ +F +P D  + W+++G+
Sbjct  595  FFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGL  654

Query  655  EGCYRFINRVFRLVINNMDLKVENTNTEQkeselskeleYNLHSTIKKVTNDIEKFHLNT  714
            EG  +F++RV+RL I   ++  EN+ + +          YN   T+K VT+++++  +NT
Sbjct  655  EGSRKFLDRVYRL-ITTKEITEENSGALD--------KVYN--ETVKAVTEQVDQMKFNT  703

Query  715  AVAACMEMTNFLYQTEKKLKTDTEKILYLQSLEILLKMLTPFVPHVCEELWGKL-GNNTF  773
            A+A   ++  F+  ++K      E  L+ +    ++++++PF PH+ EELW  L ++   
Sbjct  704  AIA---QLMVFVNAANK------EDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGES  754

Query  774  ISNQDWPSFDEtktvkdtttivvQINGKVRANIELPVGAQKEEALNSAKADSKVQKHLEG  833
            IS   WPS+DE+K V +   IVVQI+GKV+A++ ++ +  +EE  + A A+ KVQ ++ G
Sbjct  755  ISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAG  814

Query  834  KNLIKEIYVPDKLISLVVK  852
            K++IK I VP+KL+++V+K
Sbjct  815  KDIIKVIAVPNKLVNIVIK  833

882) leuS in NC_018268


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  561 bits (2117),  Expect = 9e-161, Method: Compositional matrix adjust.
 Identities = 351/869 (41%), Positives = 567/869 (66%), Gaps = 50/869 (5%)

Query  8    YNPRDVEQTARDFWADNNTFTVKEEPGKPKYYCLSMFPYPSGK-LHMGHVRNYTIGDVIS  66
            Y+   +E   + FWADN+TF    +++KPK+Y L MFPYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  67   RYQRMLGKNVMQPMGWDAFGLPAENAAIANKTAPAKWTYSNIEYMKNQLKQLGFGYDWSR  126
            R++R  G NV++PMGWDAFGLPAE+ A+     PA  T  NI   K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  127  ELATCKPDYYRWEQWFFARLYEKGLVYKKMSTVNWDPVDQTVLANEQVV-DGRGWRSGAL  185
            E+ T  P+YY+W QW+F++LYEKGL Y     VNW     T +ANE+V+ DG + R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  186  VEKKAIPQWFIRITDYAEQLLNDMDDMDGWPEQVKTMQRNWIGKSVGTELTFPLKNSEDG  245
            V +K++ QW ++IT YAE+LL+D++++D WPE +K MQRNWIGKS G+++TF +K+++ +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  246  LTVYTTRPDTLMGVTYMAIAAEHRLAKASAERHPGVARFVDECRNSKTAEADMA----TM  301
            +TV+TTRPDTL G TY  +A+EH L  A +  + + A  V + +   +  +D+A    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEA--VADYKRQASLKSDLARTDLAK  300

Query  302  EKKGIDTGFKVVHPLTQEDIPVWIANFVLTDYGTGALMAVPGHDERDHEFALKYRLPIKQ  361
            EK G+ TG   ++P+   ++PVWIA++VL+ YGTGA+MAVP+HDERD EFA ++ L I  
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  362  VISASDKPDIDVQEKAFTEKGVLVSSGKYSGMTSDEAFESIADHLEHQGIGKRTINYRLR  421
            V+ ++     +V+E AFTE G+ ++S+   G+    A+  + + LE +G+G+  + YRLR
Sbjct  361  VLEGG-----NVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  422  DWGVSRQRYWGAPIPMMTLEDGSQRpvpddqlpvllpENVEM---TGVQSPIKADPEWAK  478
            DW  SRQRYWG PIP++  EDG+  +VP+ +LP++LP   ++      +SP+    +W  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  479  TSFE-GQPATRETDTFDTFMESSWYYARFCSPNYDKGMLDPAAANYWLPVDQYIGGIEHA  537
             + E G  + RET+T      SSWYY R+  P+    + D    + WLPVD Y+GG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  538  ILHLLYARFFHKLLRDVGLVTSSEPFKQLLTQGMVLAETYSRENAKGGTVWIPPTDVIAE  597
            +LHLLYARF HK+L D+G+V + EPF++L+ QGM+L+ +Y   +++G+ V   +TD +  
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYR--DSRGALV---ATDKVEK  590

Query  598  RDDKGQITGYVHKDDGQPVHAGGVTKMSKSKNNGIDPQSIIDAHGADTVRLFMMFAAPPE  657
            RD+     ++ H + G+ ++ +  +KMSKS +N ++P+ +++  GADT+R++ MF +P +
Sbjct  591  RDG-----SFFHVETGEELEQAP-AKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLD  644

Query  658  QSLEWSDSGVEGAHRFLKRLWRLVNEQVTSAGTVPAIDVTALNDSQKNLRRKTHETIAKV  717
             S+ WS+ G+EG+++FL R+ RL+  +  +            +++   L +  +ET+  V
Sbjct  645  ASIAWSEEGLEGSRKFLDRVYRLITTKEIT------------EENSGALDKVYNETVKAV  692

Query  718  SDDISRRLTFNTAIAAVMELLNEVSKLNDSEPQARAVRQEALETAVMMLSPIVPHVCHSL  777
            ++++  ++ FNTAIA +M ++N  +K +        +  +     V +++P+ PH+ + L
Sbjct  693  TEQVD-QMKFNTAIAQLMVFVNAANKEDK-------LFSDYAKGFVQLIAPFAPHLGEEL  744

Query  778  WQSL-GHNEPVVDARWPVADESAMVRSEIQIVLQVNGKVRSKIDVPADISKADLEQLALQ  836
            WQ+L +  E++    WP  DES +V ++++IV+Q++GKV++K+ V+ D+S+ +L+++AL 
Sbjct  745  WQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALA  804

Query  837  NDNVVRFTEGNTVRKVIVVPGKLVNVVAN  865
            N++V     G+ + KVI VP KLVN+V +
Sbjct  805  NEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

883) leuS in NC_009438


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  560 bits (2114),  Expect = 1e-160, Method: Compositional matrix adjust.
 Identities = 368/868 (43%), Positives = 566/868 (66%), Gaps = 51/868 (5%)

Query  5    YNPSEIEALVQKHWHDNKTFEVTEDANKEKFYCLSMFPYPSGR-LHMGHVRNYTIGDVVA  63
            Y+ + IE+  Q  W DN TF    DA+K KFY L MFPYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RFQRLQGKNVLQPIGWDSFGLPAENAAINNKTAPAPWTYENIEYMKNQLKLLGFGYDWSR  123
            RF+R QG NVL+P+GWD+FGLPAE+ A++    PA  T ENI   K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EIATCTPEYYRWEQWFFTKLYEKGLVYKKTASVNWCPNDETVLANEQV-QDGCCWRCDTP  182
            E+ T  P+YY+W QW+FTKLYEKGL Y    +VNW  +  T +ANE+V  DG   R + P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VEQKEIPQWFIKITAYAEELLNDIDTLDGWPEQVKTMQRNWIGRSEGVEMTFGVAGHDKT  242
            V +K + QW +KITAYAE LL+D++ +D WPE +K MQRNWIG+S G ++TF V + DK 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  FDIYTTRPDTLMGVTYVAIAAGHPLAEIAAQTNPELAAFIDECKNSTTSEAELA----TM  298
            F ++TTRPDTL G TY  +A+ H+L  + A T ++ A  + + K  ++  ++LA    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHAL--VDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  299  EKRGVATGLFAIHPITGKQVPIWAANFVLMNYGTGAVMSVPGHDQRDFEFAKKYGLAIEA  358
            EK GV TG +AI+P+ GK++P+W A++VL +YGTGA+M+VP+HD+RD EFAK++ L I +
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VIKPVDGDVDISEAAYTEKGILFNSGEFDGLDFEAGFNAIANKLVAEGKGKRQVNYRLRD  418
            V+     + ++ EAA+TE G+ +NS+ +DGLD  +++  + + L AEG G+ +V YRLRD
Sbjct  361  VL----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  419  WGVSRQRYWGAPIPMVTLADGTVIPTPADQLPVLLP--EDVVMDGI-QSPIKADKEWAK-  474
            W  SRQRYWG PIP++   DGT  + P  +LP++LP   D+   G  +SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  475  TQVNGQDALRETDTFDTFMESSWYYARYCSPQADEML-DPAKANYWLPVDQYIGGIEHAC  533
            T+ +G  + RET+T      SSWYY RY  P+  E L D    + WLPVD Y+GG EHA 
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  534  MHLLYFRFFHKLLRDAGLVNSNEPAKQLLTQGMVLADAFYYINEKGARVWVSPLDVATTE  593
            +HLLY RF HK+L D G+V ++EP ++L+ QGM+L+ +  Y + +GA        + +T+
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS--YRDSRGA--------LVATD  586

Query  594  KDDKGRITKAIDKDGNELVYTGMCKMSKSKNNGIDPQVMVEKYGADTVRLFMMFASPPEL  653
            K +K R    ++ +  E +  +  KMSKS +N ++P+ +VE+YGADT+R++ MF +P + 
Sbjct  587  KVEK-RDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  654  TLEWQESGVEGAHRFIKRLWKL-ASEYIAQDNSEALDVSKLTSEQKALRREVHKTIAKVT  712
            ++ W E G+EG+++F+ R+ +L ++  I+++NS ALD            +  + T+  VT
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALD------------KVYNETVKAVT  693

Query  713  DDIGRRQMFNTAVAAVMELMNHLQKAPQTTGQDRAIIGEALSAVMRLLYPIIPHVSFTLW  772
            +++++ + FNTA+A +M ++N       ++ ++  ++++   + ++L+ P+ PH++  LW
Sbjct  694  EQVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELW  745

Query  773  NDLGNTG-SIEDSQWPVVDESALVEDSKLIVVQVNGKVRAKITVAADADKDSVEALGMND  831
            + L  +G SI    WP  DES LVE+   IVVQ++GKV+AK+ VA D  ++ ++ +++ +
Sbjct  746  QALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALAN  805

Query  832  EHVIKYLDGLTVRKVIYVPGKLLSIVAN  859
            E V   + G  + KVI VP KL++IV +
Sbjct  806  EKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

884) leuS in NC_017243


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  560 bits (2116),  Expect = 1e-160, Method: Compositional matrix adjust.
 Identities = 362/865 (42%), Positives = 559/865 (65%), Gaps = 49/865 (5%)

Query  3    YNFTTIEKKWQKFWKDNQSFKTVSKPTDKKYYVLEMFPYPSGK-MHMGHVSNYTIADSIA  61
            Y+ T+IE KWQ FW DN++FKT + ++  K+Y L+MFPYPSG  +H+GH   YT +D ++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  62   RYYKLLGYDILHPMGWDAFGMPAENAAIEHKTHPAEWTLKNIANMKEQLNLLGYSYDWDR  121
            R+ +  G ++LHPMGWDAFG+PAE+ A++   +PAE T  NIAN K Q+N LG+SYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  122  EVTTCLPDYYKWGQWFILKMYEKGLLYRKGGDVNWCDHCNTVLANEQVTPEGTCWRCDGE  181
            EV T  P+YYKW QW++ K+YEKGL Y     VNW ++  T +ANE+V P+GT  R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VTKKKLEQWYIKVTDYAEQLDADLKLLEGYWPDNVIAMQKNWIGRSVGAYINFNL-DDGK  240
            V +K + QW +K+T YAE+L  DL  ++  WP+++  MQ+NWIG+S GA + F++ D +K
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD--WPESIKDMQRNWIGKSTGANVTFKVKDTDK  241

Query  241  EFPIFTTRPDTIYGVTYMAIAWNYDGLLDMCTPEQKSAVEEFIKKSA-KID-QKTDYEKE  298
            +F +FTTRPDT++G TY  +A +   +  + T++Q  AV ++ ++++ K D  +TD  KE
Sbjct  242  DFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKE  301

Query  299  --GVFTGRYVVNPFNGEKAPLYAANFVLAEYGSGAVMAVPAHDQRDFEFAKKYNIPVKVV  356
              GV TG Y +NP NG   P+  A++VLA YG+GA+MAVPAHD+RD EFAK++N+ +  V
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  357  IQNADNSLKAENMTEAYTEDGTVVNSDILNGLSSRDAIKRAIEYATEKGFGKEKVQYKLR  416
            ++ ++          A+TEDG  +NSD+L+GL    AI + +E     G G+E+V Y+LR
Sbjct  362  LEGGNVE------EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  417  DWLISRQRYWGNPLPFVHCEKCGVVPVPESELPITLPMDIEF---TVGDNPLKKSESFVN  473
            DWL+SRQRYWG+P+P++H E     +VPESELP+ LP+  ++     G++PL +    ++
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  474  TTCPKCGGKARRETDTMDTFTCSSWYYARYTDAHNTQMPFDPETANAWLGVDQYIGGIEH  533
             T    G K+RRET+TM   + SSWYY RY D+HNT+   D E  + WL VD Y+GG EH
Sbjct  476  VTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEH  534

Query  534  ACMHLLYSRFWYKFMRDIGLVKGDEPFNRLLTQGMVLANSY-ESRELKKFYTQEQMNNKE  592
            A +HLLY+RFW K + D+G+V   EPF++L+ QGM+L+ SY +SR    + + +++++++
Sbjct  535  AVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRG--ALVATDKVEKRD  592

Query  593  ---YEKDGIRKEDIIVKMEKMSKSKANGVDPAEIIELFGADAVRIFVMFVAPPEKDKEWS  649
               ++ +    E++     KMSKS  N V+P +++E +GAD++R++ MF++P +    WS
Sbjct  593  GSFFHVET--GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWS  650

Query  650  DEGVKGSSRFLNRIWNLFLKYKDEEAFKNGKSFDYNNLSKEGQKLFRKYNktikkvtidi  709
            +EG+ GS +FL+R+  L+                 ++++ E    + K  +   K   + 
Sbjct  651  EEGLEGSRKFLDRVYRLITT---------------KEITEENSGALDKVYNETVKAVTEQ  695

Query  710  kdRFHFNTAIAALMELLNDMSVIKLANNDDYAMFKEVIRGYLILLNPIAPHMTEELYQIL  769
             D+  FNTAIA LM ++N       A N +  +F +  +G++ L+ P+APH+ EEL Q L
Sbjct  696  VDQMKFNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQAL  748

Query  770  N-FGKMILEESWVEHDEQYCKDDTFELVFQVNGKIRDRVEADVNISEDDAKTQALASEKV  828
               G  I   +W   DE    ++  E+V Q++GK++ ++    ++S ++ +  ALA+EKV
Sbjct  749  TASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKV  808

Query  829  KAFTDGKNIVKVVYVKGKLVNIVVK  853
            +A   GK+I+KV+ V  KLVNIV+K
Sbjct  809  QAEIAGKDIIKVIAVPNKLVNIVIK  833

885) leuS in NC_018645


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  560 bits (2116),  Expect = 1e-160, Method: Compositional matrix adjust.
 Identities = 360/871 (42%), Positives = 559/871 (65%), Gaps = 50/871 (5%)

Query  5    YNPELVEPKWQAYWKENQLFKVTEDPSKEKYYLLEMFPYPSGK-IHIGHVRNYTIGDVVV  63
            Y+   +EPKWQA+W +N+ FK   D+SK K+Y L+MFPYPSG  +H+GH   YT  D++ 
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYKRMKGFNVLHPMGWDAFGMPAENAAIDNNTHPAAWTYSNISAMRAQLKKMGFSYDWDR  123
            R+KR +G NVLHPMGWDAFG+PAE+ A+D   +PA  T  NI+  + Q++ +GFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EIATCRPEYYKWEQWLFLKMLEKGMAYRKESYVNWCEKCQTVLANEQV-EQDKCWRCSRP  182
            E+ T  P+YYKW QW+F K+ EKG+AY  E  VNW E   T +ANE+V  ++   R + P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VQQKKLWQWFFKITDYAQDLLVHCDQLPGWPDKVTVMQKNWIGRSVGSELKFKIHGRDED  242
            V +K ++QW +KIT YA+ LL + +++ +WP+ +  MQ+NWIG+S G+++ FK+ + D D
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LVVFTTRPDTVFGATFMCLAPEHPLVESLSKGTKTQDEVAAFVKKVS-SQERSAEGIEKY  301
            + VFTTRPDT+FGAT+  LAPEH+LV++++ + ++ + VA + ++ S   + +  ++ K 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQA-EAVADYKRQASLKSDLARTDLAK-  300

Query  302  EKEGVFTGAYCINPATLEKIPIYTANFVLMEYGTGAIMSVPAGDQRDFDFARKYGLEIRV  361
            EK GV TG+Y INP     +P+  A++VL  YGTGAIM+VPA D+RD +FA+++ L+I  
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  362  VVQPEGEELDGNTMPEAFTGSGVMVNSGEFNGLDSTKAMDVMTDWLEEKGRGKKTVSYRL  421
            V++      +GN    AFT  G+ +NS+ ++GLD + A+  M +WLE  G G+  V+YRL
Sbjct  361  VLE------GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRL  414

Query  422  RDWGISRQRFWGAPIPVIHCPDCGVVPVPEADLPIRLPEDANL--LEKGGSPLPTLDFFA  479
            RDW +SRQR+WG PIP+IH  D    +VPE++LP+ LP   ++     G SPL+ +    
Sbjct  415  RDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWL  474

Query  480  KATCPACGRQDAKRDTDTMDTFVESSWYYLRYCSPRYEKGMFDPEAVKYWAPVDQYIGGV  539
              T     +  ++R+T+TM     SSWYYLRY  P+    + D E +K W PVD Y+GG 
Sbjct  475  EVTREDGVK--GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGA  532

Query  540  EHAVLHLLYSRYFMRVLHTLGMIDFKEPFTRLLTQGMVCKETMTCPDHGFLFPEEAVKND  599
            EHAVLHLLY+R+  +VL  LG++  KEPF +L+ QGM+   T     +G L + + V + 
Sbjct  533  EHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMI-LGTSYRDSRGALVATDKVEKR  591

Query  600  DGKLVCTRCNSDVEVGRVIKMSKSKKNVVDPNELLEKYGADVTRLFSLFAAPPERDLEWN  659
            DG +       ++E +   KMSKS KNVV+P++++E+YGAD  R++ +F +P +  + W+
Sbjct  592  DGSFFHVETGEELEQAPA-KMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWS  650

Query  660  EDGVEGSNRFVNRVWRFVLEWLEKIDGIEPFNGSACDLASKQAKDLYIKANQTIKKVTED  719
            E+G+EGS +F++RV R++               ++ +++  ++  L    N+T+K VTE+
Sbjct  651  EEGLEGSRKFLDRVYRLI---------------TTKEITEENSGALDKVYNETVKAVTEQ  695

Query  720  IDKSFHFNTAISAVMELVNDLYAIDPDCVDDEVKKVILFS--IENILLLLSPIIPHFCEE  777
            +D+   FNTAI+ +M +VN          + E K   LFS     ++ L++P+ PH+ EE
Sbjct  696  VDQ-MKFNTAIAQLMVFVN--------AANKEDK---LFSDYAKGFVQLIAPFAPHLGEE  743

Query  778  LYEKLGKTGSILE-QPWPEYRKDSLETDEVLVIVQVNGKLRSKFKIGSDTEDAVVKETAL  836
            L + L  +G  +   PWP Y    L  ++V ++VQ++GK+++K+ ++ D     ++E AL
Sbjct  744  LWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVAL  803

Query  837  ADEKIKKYMGDKQPkkiivikkkQTLVNIVI  867
            A+EK++  +++K+   I VI   + LVNIVI
Sbjct  804  ANEKVQAEIAGKD--IIKVIAVPNKLVNIVI  832

886) leuS in NC_009483


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  560 bits (2116),  Expect = 1e-160, Method: Compositional matrix adjust.
 Identities = 358/858 (42%), Positives = 544/858 (64%), Gaps = 68/858 (7%)

Query  5    YLPSRVEEKWQKFWEANKSFRATEDKTREKYYLLEMFPYPSGR-IHMGHVRNYSIGDVIA  63
            Y  + +E KWQ FW  N +F++  D ++ K+Y L+MFPYPSG  +H+GH   Y+  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RFKRMKGFNVLHPMGWDAFGMPAENAAIQNKSHPAKWTYENIAYMRGQLKKMGLSYDWDR  123
            RFKR +G NVLHPMGWDAFG+PAE+ A++  ++PA  T ENIA  + Q++ +G+SYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCDVDYYKWEQLIFLQMYKKGLAYKKISSVNWCPKCETVLANEQV-EDGCCWRCDSN  182
            E+ T D +YYKW Q IF ++Y KGLAY    +VNW     T +ANE+V  DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VDQKELEQWSFRITDYAEELLEYTYKLPGWPERVLTMQRNWIGRSTGCEIDFPIEGQMDK  242
            V +K + QW ++IT YAE LLE      +WPE +  MQRNWIG+STG ++ F + +    
Sbjct  184  VVRKPMRQWMLKITAYAERLLE-DLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  IKVFTTRQDTLFGATFMSLAPEHPMALELTTPENMATVAAFIEKVKKTDRIRRTAEDFEK  302
            + VFTTR DTLFGAT+  LAPEH++   +TT+++  +VA +  +      + RT    EK
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEK  302

Query  303  EGVFTGSYCINPVTNRRMPVYLANFVLTDYGTGAVMAVPTHDQRDFEFARKYDIPMGVVI  362
             GV TGSY INPV  + MPV +A++VL+ YGTGA+MAVP+HD+RD EFA+++++ +  V+
Sbjct  303  TGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL  362

Query  363  QPEGEALDPQTMAEAFTAEGIMVNSGRFDGLKSGAAKEQIADYLEKEGIGKKTVNYRLRD  422
              EG  ++      AFT +G+ +NS+ +DGL  ++A  ++ + LE EG+G+  V YRLRD
Sbjct  363  --EGGNVE----EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  423  WGISRQRYWGNPIPMIYCDLCGAVPVPETDLPVVLPMDATF--TGEGGNPLDKVDSFVNT  480
            W +SRQRYWG+PIP+I  +   + +VPE++LP+VLP+   +  +G G +PL +V   ++ 
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  481  TCPQCGEAARRETDTMDTFVESSWYFLRYCCPDFVSGPLDKEKTEYWMSVDQYIGGIEHA  540
            T  + G  +RRET+TM     SSWY+LRY  P+      D E    W++VD Y+GG EHA
Sbjct  477  TRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  541  VMHLLYARFFTKVLRDLGYCDIDEPFTNLLTQGMVI-------------------KDG--  579
            V+HLLYARF  KVL DLG     EPF +L+ QGM++                   +DG  
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSF  595

Query  580  -------------AKMSKSKGNVVDPNALIDKYGADTARLFSLFAAPPEKDLDWSDQGVD  626
                         AKMSKS  NVV+P+ ++++YGADT R++ +F +P +  + WS++G++
Sbjct  596  FHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLE  655

Query  627  GSFRFLNRVWKLVYDTLPIIGGAGALDPAGLTNEGKGLRRQVHKTIRKVTEDIEERFHFN  686
            GS +FL+RV +L+         +GALD            +  + T++ VTE++++   FN
Sbjct  656  GSRKFLDRVYRLITTKEITEENSGALD------------KVYNETVKAVTEQVDQ-MKFN  702

Query  687  TAIAATMELVNTIQSFEPKNSPQNAPVLKEAIESVVMLLAPFVPHFTEELWAQL-GNNKS  745
            TAIA  M +VN+        + ++  ++ +   + V L+APF PH+ EELW  L ++  S
Sbjct  703  TAIAQLMVFVNA--------ANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGES  754

Query  746  LEQAGWPAFDSAAAIDEELLVVVQVNGKLRGKLTVAVTASEDDVKGAALADERVKPFIEG  805
            +    WP++D +  +++++ +VVQ++GK+++KL VA   S ++++  ALA+E+V++ I G
Sbjct  755  ISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAG  814

Query  806  KSVKKIVYVPGKLVNIVV  823
            K + K++ VP KLVNIV+
Sbjct  815  KDIIKVIAVPNKLVNIVI  832

887) leuS in NC_017067


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  560 bits (2115),  Expect = 1e-160, Method: Compositional matrix adjust.
 Identities = 359/867 (42%), Positives = 563/867 (65%), Gaps = 47/867 (5%)

Query  8    YNPREVEQTARTFWETNETFKVKEEPGKPKYYCLSMFPYPSGK-LHMGHVRNYTIGDVIS  66
            Y+   +E   ++FW  N+TFK   +++KPK+Y L MFPYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  67   RYQRMQGKNVMQPMGWDAFGLPAENAAIANKSAPAKWTRSNIDYMKNQLKQLGFGYDWSR  126
            R++R QG NV++PMGWDAFGLPAE+ A+   + PA  T  NI   K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  127  ELATCDPEYYRWEQWFFARLYEKGLVYKKMSTVNWDPVDQTVLANEQVV-DGRGWRSGAL  185
            E+ T DP+YY+W QW+F++LYEKGL Y     VNW     T +ANE+V+ DG + R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  186  VEQKKIPQWFIRITDYAEELLNDLEDMEGWPEQVKTMQRNWIGKSVGTELTFPLKEQEGG  245
            V +K + QW ++IT YAE LL+DLE+++ WPE +K MQRNWIGKS G+++TF +K+ + +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  246  LTVYTTRPDTLMGVSY--MavaaehplakaaaERHRDVAEFVDQCR-NSKVAEAELATME  302
            +TV+TTRPDTL G +Y  +A       A +++++   VA++  Q   +S +A ++LA  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  303  KKGIDTGFKAIHPLTQEEIPVWVANFVLTDYGTGALMAVPGHDERDHEFAVKYKLPIKQV  362
            K G+ TG  AI+P+   E+PVW+A++VL+ YGTGA+MAVP+HDERD EFA +++L I  V
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  363  IAPNDSRDIDIQEQAFTEKGVLVSSGKYSGLTSEEAFEEIADYLEAQGIGKRTVNYRLRD  422
            +        +++E AFTE G+ ++S+   GL    A+  + + LEA+G+G+  V YRLRD
Sbjct  362  LEGG-----NVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  423  WGVSRQRYWGAPIPMMTLEDGTEMPVPDDQLPVRLPEDVEM---DGVQSPIKADPEWCK-  478
            W  SRQRYWG PIP++  EDGT  +VP+ +LP+ LP   ++   +  +SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  479  TEYNGQPATLETDTFDTFMESSWYYARFCSPNYDKGMLDPAAANYWLPVDQYIGGIEHAI  538
            T  +G  +  ET+T      SSWYY R+  P+    + D    + WLPVD Y+GG EHA+
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  539  LHLLYARFFHKLLRDVGLVNSSEPFKRLLTQGMVLAETYYRNEANGGKTWFNPADVTVER  598
            LHLLYARF HK+L D+G+V + EPF++L+ QGM+L+ +Y   ++ G+   + ++D    R
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY--RDSRGA---LVATDKVEKR  591

Query  599  DGKGQVVRAVLKSDGEPVEIGGVTKMSKSKNNGIDPQAIIDQHGADTVRLFMMFAAPPEQ  658
            DG    V +     GE +E  + +KMSKS +N ++P+ +++Q GADT+R++ MF +P + 
Sbjct  592  DGSFFHVET-----GEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  659  SLEWSDSGVEGAHRFLKRLWRMVNEHTASGEAPAVDPASLNGAQKDLRRKTHETIAKVSD  718
            S+ WS+ G+EG+++FL R+ R++     + E ++            L +  +ET+  V++
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLITTKEITEENSG-----------ALDKVYNETVKAVTE  694

Query  719  DISRRLTFNTAIAAVMELLNEVGRLSDDEPQTRAVRQEALDTAVLVLSPIVPHICHNLWQ  778
            ++  ++ FNTAIA +M ++N   +          +  +     V +++P+ PH+ ++LWQ
Sbjct  695  QVD-QMKFNTAIAQLMVFVNAANK-------EDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  779  AL-GHSDTVVDASWPVADESAMVRSEIEVVLQVNGKVRAKENVPADIGKADLEKLALENE  837
            AL + ++++   +WP  DES +V +++E+V+Q++GKV+AK  V+ D+++ +L+ +AL NE
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  838  NVMRFTDGKTVRKVIVVPGKLVNVVAN  864
            +V     GK + KVI VP KLVN+V +
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVIK  833

888) leuS in NC_016077


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  560 bits (2115),  Expect = 1e-160, Method: Compositional matrix adjust.
 Identities = 351/863 (41%), Positives = 544/863 (64%), Gaps = 72/863 (8%)

Query  6    YEPHKAEAKWQKYWEDHHTYKVSNDDPRPKYYVLEMFPYPSG-NLHMGHVRNYSIGDVVA  64
            Y+    E+KWQ +W D+HT+K + D ++PK+Y L+MFPYPSG  LH+GH   Y+  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  65   RFRTMRGYNVLHPMGFDSFGMPAENAAIKHNIPPAKWTLENIANMEDQQKRMGLSYDWDR  124
            RF+  +G NVLHPMG D+FG+PAE+ A+     PA  T ENIAN   Q + +G+SYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  125  EVKTCMEDYYKWTQWFFELMYKRGLAVKKTAPVNWCEKCNTVLANEQVI-DGKCWRCDTP  183
            EV+T   +YYKWTQW+F  +Y +GLA     PVNW E   T +ANE+V+ DG   R + P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  184  VVKKDLSQWFFKITDYADEllkdldllkGWPEPVKTMQRNWIGRSEGLEFSFDCPDLGTK  243
            VV+K + QW +KIT YA E L +     +WPE++K MQRNWIG+S G + +F   D +  
Sbjct  184  VVRKPMRQWMLKITAYA-ERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  244  LPVYTTRPDTIYGVTFVVIPPEHPLVAKILENNPKRAELEAFCDKVRNTSDIERTSADSE  303
            + V+TTRPDT++G T+ V++PEH+LV  I  ++   A +  +  +    SD+ RT    E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEA-VADYKRQASLKSDLARTDLAKE  301

Query  304  KLGMYTGYDCVHPLTGHKVEIWITNYVLFDYGTGAVMGVPSGDHRDWMFASKYGIKKILT  363
            K G+ TG   ++P+ G  + +WI++YVL  YGTGA+M+VP+ D+RDW FA ++ +  I  
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  364  LQPKDHELKLEEMDDAYTEKDGVLVNSGPFTGMEMHKAMGAIMDYMEEKGLGKRRVNYRL  423
            L+  + E      + A+TE DG+ +NS+ + G++   A++ +++ +E  G+G+  V YRL
Sbjct  362  LEGGNVE------EAAFTE-DGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRL  414

Query  424  RDWLISRQRYWGAPIPVINCPQCGEVLVPEKDLPVKLPT--DVKFAAGAKSPLATSESFV  481
            RDWL+SRQRYWG PIP+I+  +     VPE +LP+ LP   D++ ++ + SPLA     +
Sbjct  415  RDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWL  474

Query  482  HCTCPKCGGPATRELDTMDTFVCSSWYYLRYTDPHNDQAPFSHEAVDHWMSVDQYIGGIE  541
            + T    G  + RE +TM     SSWYYLRY DPHN +    +E + +W++VD Y+GG E
Sbjct  475  EVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAE  533

Query  542  HAILHLLYSRFFVKVLRDAGLVKVDEPFTNLLTQGMVI-------------------KDG  582
            HA+LHLLY+RF  KVL D G+V   EPF +L+ QGM++                   +DG
Sbjct  534  HAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDG  593

Query  583  ---------------AKMSKSLGNVVSPEEIIGKYGADTARLFIMFAAPVERELEWSDQG  627
                           AKMSKSL NVV+P++++ +YGADT R++ MF +P++  + WS++G
Sbjct  594  SFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEG  653

Query  628  VEGSFRFLNRVWRIVYHFQDELQKKVKTYDVKEL-DEAGREMRHILHVSLKKITEDLDSR  686
            +EGS +FL+RV R++                KE+ +E +  +  + + ++K +TE++D +
Sbjct  654  LEGSRKFLDRVYRLI--------------TTKEITEENSGALDKVYNETVKAVTEQVD-Q  698

Query  687  FNFNTAISTMMELVNALYAYKDKAKKVHPGLIWEVITDLLLVMAPFVPHITEELWHGTID  746
             +FNTAI+ +M +VNA     +K  K+ +    +   +++ ++APF PH+ EELW++   
Sbjct  699  MKFNTAIAQLMVFVNA----ANKEDKLFS----DYAKGFVQLIAPFAPHLGEELWQALTA  750

Query  747  DSESIHKQAWPKYDEEAIKVDEVEVLVEVNGKPKDRIMVDPEMDKEALGKVALESKAVKE  806
             +ESI   +WP YDE  +  ++VE++V+++GK K +++V  ++ +E L  VAL +  V+ 
Sbjct  751  SGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQA  810

Query  807  AIGSGKVVRVIAVPGRLVNIVVK  829
             I++  +++VIAVP +LVNIV+K
Sbjct  811  EIAGKDIIKVIAVPNKLVNIVIK  833

889) leuS in NC_011653


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  560 bits (2113),  Expect = 2e-160, Method: Compositional matrix adjust.
 Identities = 371/842 (45%), Positives = 540/842 (65%), Gaps = 70/842 (8%)

Query  23   FETPQYSEKPKFYDLVMFPYPSGT-LHVGHVKNYVIGDIVARYKRMKGFNVLHPFGYDAF  81
            F T   + KPKFY L MFPYPSG+ LHVGH   Y   DI++R+KR +G NVLHP G DAF
Sbjct  23   FKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSRFKRAQGHNVLHPMGWDAF  82

Query  82   GLPAENAAIKNKIHPEVWTFKNIETIRNQIKKIGISYDWKREIATCTEDYYKWTQWLFVK  141
            GLPAE+ A+    +P   T  NI  ++ QI+ +G+SYDW RE+ T   +YYKWTQW+F K
Sbjct  83   GLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTK  142

Query  142  MYEKGLAYKKKAAVNWCPSCQTVLANEQVV-DGKCERCGTEVTLKHLEQWYFKITDYAER  200
            +YEKGLAY    +VNW     T +ANE+V+ DG  ER G  V  K + QW +KIT YAER
Sbjct  143  LYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAER  202

Query  201  LLNDLERLEGWPENVKTMQKNWIGKSTGAEIDFKVDGLDMSIRVFTTRPDTIWGVTFMAI  260
            LL+DLE ++ WPE++K MQ+NWIGKSTGA++ FKV + D  + VFTTRPDT+ G T+  +
Sbjct  203  LLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVL  261

Query  261  APESPLvetlvtedkkeeleeflkkvsleDRFKRTSLEAEKEGFFLGRYAINPVTGEKIP  320
            APE +LV+++ T D+ E + ++ ++ SL   + RT L  EK G   G YAINPV G  +P
Sbjct  262  APEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAINPVNGKEMP  321

Query  321  IYVANYILYEYGTGAIMAVPAHDQRDFDFAKKYNIPIRLVIDNPESPIDVEKMEKAYEDE  380
            + +A+Y+L  YGTGAIMAVPAHD+RD +FAK++N+ I  V++  +        E A+ ++
Sbjct  322  VWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVE------EAAFTED  375

Query  381  GIMVNSGPFNGISSKEAIEKIIDYLEEKNIGKRSVQYKLRDWLISRQRYWGAPIPVVYCE  440
            G+ +NS+ ++G+    AI K+++ LE   +G+ +V Y+LRDWL+SRQRYWG PIP++  E
Sbjct  376  GLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWE  435

Query  441  KCGTVAVPEEQLPVKLP--KDVEFLPTGQSPLSLDEQFLNTTCPKCGGPARREADTMDTF  498
               + AVPE +LP+ LP  KD+    TG+SPL+   + L+ T    G  +RRE++TM   
Sbjct  436  DGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED-GVKGRRETNTMPQW  494

Query  499  VDSSWYYLRYVNPNLEDKPFESKDVNYWLPVDQYIGGVEHAVLHLLYSRFITKVLHDMGY  558
             +SSWYYLRY++P+  +K  +   ++ WLPVD Y+GG EHAVLHLLY+RF  KVL D+G 
Sbjct  495  AGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGV  554

Query  559  VDFDEPFTNLFTQGMI----YKDGW------------------------------KMSKS  584
            V   EPF +LF QGMI    Y+D++                              KMSKS
Sbjct  555  VPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKS  614

Query  585  KGNVVSPDDMIEKYGADTLRTYILFMAPPEKDAEWSDAGIEGVHRFLKRLWNNIYSVLEK  644
              NVV+PDD++E+YGADTLR Y +FM+P +    WS+ G+EG ++FL R    +Y ++  
Sbjct  615  LKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR----VYRLI-T  669

Query  645  IKNVSAEKIELKNKLEKDLRRKLHQSIKKITEDIEGGFKFNTAIAGLMELNNSFSDYLNK  704
             K+++ E+          L +  ++++K +TE+++   KFNTAIA LM + N+      +
Sbjct  670  TKEITEENSG-------ALDKVYNETVKAVTEQVD-QMKFNTAIAQLMVFVNA-----AN  716

Query  705  TEEKDLNLPLLRELVEKLALILSPFAPHMAEEIWHDLGNDTLIVN-EEWPKYDEKALEVD  763
             E+K     L+ +    +  +++PFAPH++EE+W+ L      ++   WP YDE  L  +
Sbjct  717  KEDK-----LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVEN  771

Query  764  EVTVIIQINGKVRGKINVDVNADEETVKKIAFEEPKVSSYIEGKEIVKVIYVKNKLLNIV  823
            +V +++QI+GKV++K+ V  +   E ++ +A+ + KV + I GK+I+KVI V NKL+NIV
Sbjct  772  DVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIV  831

Query  824  VK  825
            +K
Sbjct  832  IK  833

890) Adeg_1804 in NC_013385


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  560 bits (2113),  Expect = 2e-160, Method: Compositional matrix adjust.
 Identities = 357/831 (43%), Positives = 546/831 (66%), Gaps = 68/831 (8%)

Query  32   KPKYYCLEMFPYPSGK-LHMGHVRNYAIGDVVARFKRMQGYSVLHPMGWDAFGLPAENAA  90
            KPK+Y L+MFPYPSG  LH+GH   Y+  D+++RFKR QG +VLHPMGWDAFGLPAE+ A
Sbjct  31   KPKFYALDMFPYPSGAGLHVGHPEGYTATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYA  90

Query  91   IKHGIHPHDWTWQNISFMREQLKQLGFSYDWHREIATCHPDYYRWTQWLFLQFFHRGLAY  150
            +  G +P + T +NI+  + Q++ LGFSYDW+RE+ T +P+YY+WTQW+F +++++GLAY
Sbjct  91   MDTGNDPAEFTAENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAY  150

Query  151  RKKAPVNWCPSCATVLANEQVV-GGVCERCKTPVVPRELEQWFLRITAYAERLLQDLDKL  209
                PVNW    +T +ANE+V+ +G  ER   PVV + + QW L+ITAYAERLL+DL+ +
Sbjct  151  EAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDLEEV  210

Query  210  TGWPEKVKVMQRNWIGKSEGALINFPVVGREEGITVFTTRPDTLYGVTYLVLAPEHPLVM  269
             +WPE +K MQRNWIGKS GA + F V + + ++TVFTTRPDTL+G TY VLAPEH+LV 
Sbjct  211  -DWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHALVD  269

Query  270  ELAAEGRREEVSRFVERARLLPALSRTAGEQEKEGLFLGAFCRHPLTGEDLPIYVANYVL  329
             +++ ++ E V+ +  +A L + L+RT   +EK G+  G++  +P+ G ++P+ +A+YVL
Sbjct  270  AITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAINPVNGKEMPVWIADYVL  329

Query  330  MEYGTGAVMGVPAHDQRDFEFARKFGLPIKVVIQPPGAELDPDTMTAAYVDEGVLVNSGP  389
              YGTGA+M+VPAHD+RD EFA++F L I  V++    E       AA+ ++G+ +NS+ 
Sbjct  330  ASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVE------EAAFTEDGLHINSDF  383

Query  390  FDGKPNLQAMEEIVAYLEEKGLGKRQVTYRLRDWLISRQRYWGAPIPIVYCDRCGIvpvp  449
            +DG  +  A+  +V  LE  G+G+ +VTYRLRDWL+SRQRYWG PIPI+  +     +VP
Sbjct  384  LDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVP  443

Query  450  eeqlpvllpYNVAFKP--TGESPLKDCPEFVNTTCPRCGAPARRETDTMDTFICSSWYYF  507
            E +LP++LP    ++P  TGESPL +  + ++ T    G  +RRET+TM     SSWYY+
Sbjct  444  ESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED-GVKGRRETNTMPQWAGSSWYYL  502

Query  508  RYTSPKEDKAPWDKTKVDYWLPVDQYIGGVEHAILHLLYSRFFTKFLYDIGLVSCDEPFT  567
            RY  P +     D   +  WLPVD Y+GG EHA+LHLLY+RF  K LYD+G+V+  EPF 
Sbjct  503  RYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQ  562

Query  568  NLLTQGMVL-------------------KDG---------------AKMSKSKGNIVSPE  593
            +L+ QGM+L                   +DG               AKMSKS  N+V+P+
Sbjct  563  KLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPD  622

Query  594  EIIEHYGADTTRLFILFAAPPERDLEWSDEGVEGCARFLNRVWRLVRSLIPVVQGAGEPA  653
            +++E+YGADT R++ +F +P +  + WS+EG+EG  +FL+RV RL+ +     + +G   
Sbjct  623  DVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITEENSG---  679

Query  654  ESLSPPNRELRRLTHRTIERVTRDIEEFGLNTAVSAIMEFTNGLARYCEEVRPEERDPGT  713
                     L ++ + T+  VT ++++  +NTA++ +M F          V + +++   
Sbjct  680  --------ALDKVYNETVKAVTEQVDQMKFNTAIAQLMVF----------VNAANKEDKL  721

Query  714  LREAVETLILLLAPFAPYMAEELWEQL-GKKESVHRQSWPTYDPKLTVADQVEVVIQING  772
            + +    ++ L+APFAP ++EELW+ L +  ES+   +WP+YD    V ++VE+V+QI+G
Sbjct  722  FSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKG  781

Query  773  KVRGRvmvaatatpaemeeaarrepRIKQLLAGKEVRKVITVPGKLVNFVV  823
            KV+++++VA   +  E++E A  + +++  +AGK++ KVI+VP KLVN+V+
Sbjct  782  KVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

891) leuS in NC_013260


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  560 bits (2114),  Expect = 2e-160, Method: Compositional matrix adjust.
 Identities = 354/842 (43%), Positives = 548/842 (66%), Gaps = 43/842 (5%)

Query  5    YDFKTIEAKWQRVWEESGAFAVMEEPERRKFYLLEMYPYPSGR-IHMGHVRNYAIGDVLA  63
            YD  +IE+KWQ  W ++ +F    ++ + KFY L+M+PYPSG  +H+GH   Y+  D+L+
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RFLRMRGYNVLHPMGWDSFGLPAENAAIEHRTQPARWTSDNIAYMRTQLKRMGFSYDWQR  123
            RF R +G NVLHPMGWD+FGLPAE+ A++   +PA  T++NIA  + Q++ +GFSYDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EITCSDPAYYRWGQWLFLKLYEKGLVYKKSSAVNWCEVCQTVLANEQV-EGGLCWRDGTS  182
            E+  +DP YY+W QW+F KLYEKGL Y    +VNW E   T +ANE+V  +G   R+G +
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VVQKELPGWFFRITAYADELLSSLDNLSGWPEPVKVMQRNWIGKSVGAEVRFPLADREGA  242
            VV+K +  W ++ITAYA+ LL  L+++ +WPE++K MQRNWIGKS GA+V F + D +  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTIFTTRQDTLFGVTFMVLAPEHPDALTLAQGTPQEPQVRAFIERITREDRLQRTATDVD  302
            +T+FTTR DTLFG T+ VLAPEH+   +++ +   E+ V  +  + +    L RT    +
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEA-VADYKRQASLKSDLARTDLAKE  301

Query  303  KEGVFTGAYAINPLTHERIPVWIGNFVLLEYGTGAIMAVPSNDQRDFEFAQKYGLPVRLA  362
            K GV TG+YAINP+    +PVWI+++VL  YGTGAIMAVP++D+RD EFA+++ L +   
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  363  VKPVDVDPDERHLQQAYEGEGVLVNSGPFTGMASQQAREAIADFLEREAIGKRTVNYRLR  422
            +   +V+      + A+  +G+ +NS+ + G+    A   + + LE E++G+  V YRLR
Sbjct  362  LEGGNVE------EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  423  DWGISRQRYWGNPIPIIYCDGCKTVPVPYRDLPVILP--QDVRITMKGGSPLRKVAEFTD  480
            DW +SRQRYWG+PIPII  ++  + +VP  +LP++LP  +D+R +  G SPL +V++  +
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  481  VLCPRCGGPARRETDTMDTFVDSSWYFLRFTSPKDEDGPVTPARVNYWMPVDQYIGGIEH  540
            V     G  +RRET+TM    +SSWY+LR+  P + +       ++ W+PVD Y+GG EH
Sbjct  476  V-TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEH  534

Query  541  AVLHLLYARFFTKAVRDLGLIAVDEPFRRLLTQGMVCKETYRCAEHGFRLPEEVDASSCC  600
            AVLHLLYARF  K + DLG+++  EPF++L+ QGM+   +YR +  ++   + V+     
Sbjct  535  AVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGS  594

Query  601  ---RACGRPVKIGRIEKMSKSKKNVVDPEDLLTQYGADTARIFCLFAAPPERDLEWSDQG  657
                  G  +  +   KMSKS KNVV+P+D++ QYGADT R++ +F +P +  + WS++G
Sbjct  595  FFHVETGEELEQAP-AKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEG  653

Query  658  VEGSFRFLCRIVRLIEDQEALLKEPNPSIAFQKLIAGRALYRKAQQTIKRVTEDIEDDFH  717
            +EGS +FL R+ RLI  +E  + E N++ A++K      +Y   ++T+K VTE++ D+  
Sbjct  654  LEGSRKFLDRVYRLITTKE--ITEENSG-ALDK------VY---NETVKAVTEQV-DQMK  700

Query  718  FNTAISALMELANEIGRFELVGSADDADERRVAYSYAVETlllllSPFAPHLCEELWERL  777
            FNTAI+ LM + N   +           E ++   YA   ++ L++PFAPHL EELW+ L
Sbjct  701  FNTAIAQLMVFVNAANK-----------EDKLFSDYA-KGFVQLIAPFAPHLGEELWQAL  748

Query  778  GHDGSIFQ-APWPSYDPaiitaeeivvvvqiDGKVRSRLVMPADADDTAMREAALSDERV  836
               G  +   PWPSYD + +  +++ +VVQI GKV+++LV++ D     ++E AL++E+V
Sbjct  749  TASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKV  808

Query  837  KG  838
            ++
Sbjct  809  QA  810

892) Marky_1980 in NC_015387


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  559 bits (2112),  Expect = 2e-160, Method: Compositional matrix adjust.
 Identities = 396/878 (46%), Positives = 569/878 (65%), Gaps = 54/878 (6%)

Query  4    YNPHAIEPKWQAYWQEKGLMKAKEEGEKQ--YVLMMFPYPSG-DLHMGHLKNYTMGDVLA  60
            Y+  AIEPKWQA+W ++   K+  ++ K   Y L MFPYPSG +LH+GH   YT  D+L+
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  61   RFKKQQGYTVLHPMGWDAFGLPAENAALKFGVHPAEWTFKNIASAKESLRLMGILYDWDR  120
            RFK+ QG  VLHPMGWDAFGLPAE+ A+  G +PAE T  NIA+ K  +  +G+ YDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  121  EVTTCTPEYYRWNQWIFLKMYEKGLVYRAKGLVNWCPKCQTVLANEQVVDGRCWRHEDTL  180
            EV T  P+YY+W QWIF K+YEKGL Y A   VNW     T +ANE+V+ +    + +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  181  VEKKELEQWYLRITAYADRLLQDLEQLTGWPEKVKAMQRAWIGRSEGAEIAFPVKGRDVK  240
            V +K + QW L+ITAYA+RLL+DLE++ +WPE +K MQR WIG+S GA+++F VK+ D  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  241  IPVFTTRPDTLFGATFLVLAPEHPMLLELTaperraeveayvaaaKQKTELEREALGREK  300
            + VFTTRPDTLFGAT+ VLAPEH+++  +T++++   V  Y   A  K++L R  L++EK
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEK  302

Query  301  TGVFTGAYAINPATGEEIPIWTADYVLYGYGTGAIMAVPAHDQRDFEFARRFNLPVRVVI  360
            TGV TG+YAINP  G E+P+W ADYVL +YGTGAIMAVPAHD+RD EFA++FNL +  V+
Sbjct  303  TGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL  362

Query  361  QpaegglaepleaayeepgVMVNSGPFDGTPSVEGKGRVIRWLEEKGLGRARVTYRMRDW  420
            +      ++  EAA+ E G+ +NS+ +DG     + ++++ WLE  G+G   VTYR+RDW
Sbjct  363  E-----GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDW  417

Query  421  LISRQRYWGTPIPMIHCEACGIVPVPYEDLPVVLPEIQDVEEIRPKGKSPLEAHPEFYET  480
            L+SRQRYWG PIP+IH E     +VP  +LP+VLP  +D+      G SPL    +  E 
Sbjct  418  LFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRP-SGTGESPLANVTDWLEV  476

Query  481  TCPHCGRPARRdtdtmdtffdSSWYYLRYADPHN-DRLPFDPEKADFWLPVDQYIGGIEH  539
            T  +  + +RR+T+TM    +SSWYYLRY DPHN ++L+ D E    WLPVD Y+GG EH
Sbjct  477  TREDGVK-GRRETNTMPQWAGSSWYYLRYIDPHNTEKLA-DEELLKQWLPVDIYVGGAEH  534

Query  540  AVLHLLYSRFFTKFLHDIGMVRVEEPFKGLFTQGMVMGWTDYGPVQVEGETVRLSEEARV  599
            AVLHLLY+RF  K L D+G+V   EPF+ LF QGM++G T Y              ++R 
Sbjct  535  AVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILG-TSY-------------RDSRG  580

Query  600  RLDLESGTLTKAELAKMGAELRAHEDGTTHLWKPAVMSKSLGNGVMVGPFVKEQGADIAR  659
             L      ++   + K ++ +   E G      PA MSKSL N V  +  V + GAD  R
Sbjct  581  AL------VATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLR  634

Query  660  ITILFAAPPENDMVWTEEGVSGAWRFLNRVWRRFAEDKDALTTLEDAFDPAALSGADRAL  719
            +  +F +P +  + W+EEG+ G+++FL+RV R        L T  +  +  +      AL
Sbjct  635  VYEMFMGPLDASIAWSEEGLEGSRKFLDRVYR--------LITTKEITEENS-----GAL  681

Query  720  YRALHRTLKKVGEDTENLRFNTAIAALMELLNALYEYRHKHAPSPVYKRAVRYYLQMLAP  779
             +  + T+K V E+ ++++FNTAIA LM ++NA       +    ++    + ++Q++AP
Sbjct  682  DKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNA------ANKEDKLFSDYAKGFVQLIAP  735

Query  780  FAPHLAEEVWHWLDAR--SVFEVPWPEVDEDALVEDTFELVVQVNGRVRGRAVLPTNVGe  837
            FAPHL+EE+W+ L A   S+  VPWP  DE  LVE+  E+VVQ++G+V+++ V++ +++ 
Sbjct  736  FAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSR  795

Query  838  eeakqaakaieNVRRHLEGRTIVKEIYVPGKLLNIVVK  875
            EE ++ A A E+V+ ++ G+ I+K I VP KL+NIV+K
Sbjct  796  EELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

893) Chro_4832 in NC_019695


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  559 bits (2111),  Expect = 2e-160, Method: Compositional matrix adjust.
 Identities = 361/847 (43%), Positives = 553/847 (66%), Gaps = 47/847 (5%)

Query  5    YNPAAIEEKWQKTWVEQGIDKTEENQDKPKFYALSMFPYPSGS-LHMGHVRNYVITDVIA  63
            Y+ +AIE KWQ  W ++   KT  +  KPKFYAL MFPYPSG+ LH+GH   Y  TD+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RLKRMQGYRVLHPMGWDAFGLPAENAAIKNNIPPAKWTQRNIAQMRDQLKRLGLSIDWDK  123
            R+KR QG  VLHPMGWDAFGLPAE+ A+     PA  T  NIA+ + Q++ LG+S DWD+
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCSPDYYKWTQWIFLQFLQAGLAYQKEAAVNWDPVDQTVLANEQVDSEGRSWRSGAK  183
            E+ T  P+YYKWTQWIF ++ + GLAY+ E +VNW     T +ANE+V ++G S R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  184  VEKKLLKQWFLKITDYAEELLQDLDQLIGWPERVKLMQANWIGKSTGAYLEFPIVGSSEK  243
            V +K ++QW LKIT YAE LL+DL++ ++WPE +K MQ NWIGKSTGA + F + ++   
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEE-VDWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  244  IGVFTTRPDTVYGVTYVVLAPEHPLTRQVTTPDRKAAVEAFIQEVAAESELERTAEDKPK  303
            + VFTTRPDT++G TY VLAPEH+L   +TT+D+  AV  + ++ +  S+L RT   K K
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEK  302

Query  304  RGIPTGGMAINPFTGAEIPIWIADYVLYEYGTGAVMGVPAHDTRDFQFAQGNNLPIQVVI  363
             G+ TG+ AINP  G E+P+WIADYVL  YGTGA+M+VPAHD RD +FA  +++ ++++ 
Sbjct  303  TGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFA--KQFNLDIIP  360

Query  364  VPPNNDVEMLRVTPLQEAYTEPGIMVNSGSFDGTDSVKGKQAVIEYAEKQGWGKARIQYR  423
            V    +VE       + A+TE G+ +NS+ +DG D   +   ++E  E +G G+  + YR
Sbjct  361  VLEGGNVE-------EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYR  413

Query  424  LRDWLISRQRYWGAPIPVVHCPNCGIVPVPEADLPVRLP--EDIEFTGRGGSPLAQLSSW  481
            LRDWL+SRQRYWG PIP++H  +    +VPE++LP+ LP   DI  +G G SPLA+++ W
Sbjct  414  LRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDW  473

Query  482  VNVPCPTCGTPAKRETDTMDTFIDSSWYFLRFPDATNDKLVFDSARVNDWMPVDQYVGGI  541
            ++V     G  ++RET+TM    +SSWY+LR+ D+ N   + D   +++W+PVD YVGG 
Sbjct  474  LEVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGA  532

Query  542  EHAILHLLYSRFFTKVLRDRPKGGTEGDRNLLNFDEPFQRLLTQGMVQGLTYMNPNKADK  601
            EHA+LHLLY+RF  KVL          D  ++   EPFQ+L+ QGM+ G +Y    +  +
Sbjct  533  EHAVLHLLYARFWHKVLY---------DLGVVPTKEPFQKLFNQGMILGTSY----RDSR  579

Query  602  DKWVPTSIVNADDPR--DPQTGEPLKLVYATMSKSKGNGVAPEEVIAKYGVDTARMFILF  659
            +  V+T  V+  D    + +TGE L    A MSKS  N V P++V+ +YG DT R++ +F
Sbjct  580  GALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMF  639

Query  660  KAPPEKDLEWDEADVQGQFRFLNRVWQLVTEFAQQPTVKETSIKNPKSKIEKDLRRAIHT  719
             +P +  + W E +++G  +FL+RV +L+       T KE +  N+ +     L +  + 
Sbjct  640  MGPLDASIAWSEEGLEGSRKFLDRVYRLI-------TTKEITEENSGA-----LDKVYNE  687

Query  720  AIQAITEDLEGEYQFNTAVSELMKLSNALADATCKDSPVYAEGIKTLILLLAPFAPHIAD  779
            +++A+TE+++ + +FNTA+++LM     + +A+ K+  ++++  K ++ L+APFAPH+++
Sbjct  688  TVKAVTEQVD-QMKFNTAIAQLM----VFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGE  742

Query  780  ELWHAI-ANQESVHKQSWLKADPDALVADEMTLVIQINGKTRGTIQVPAQADRQMQEKLA  838
            ELW+A+ A+ ES+   +W   D   LV +++ +V+QI+GK ++ + V+ +  R+  + +A
Sbjct  743  ELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVA  802

Query  839  RESEPAQ  845
              +E  Q
Sbjct  803  LANEKVQ  809

894) leuS in NC_021286


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  559 bits (2112),  Expect = 2e-160, Method: Compositional matrix adjust.
 Identities = 360/864 (42%), Positives = 571/864 (67%), Gaps = 46/864 (5%)

Query  5    YNPSKIESAMQKRWQEQDVFTAKEQPGKDKFYCLSMFPYPSGK-LHMGHVRNYTLGDVIS  63
            Y+ + IE+  Q  W +++ F +  +++K KFY L MFPYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RHQRMLGKNVMQPMGWDAFGLPAENAAIQNKTAPAKWTYQNIDYMREQLKSLGFGYDWNR  123
            R +R  G NV++PMGWDAFGLPAE+ A++    PA  T +NI   + Q+++LGF+YDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCSPDYYRWEQWFFTKLYEKGLVYKKNATVNWDPVDQTVLANEQVI-DGRGWRSGAK  182
            E+ T  P+YY+W QW+FTKLYEKGL Y  +  VNW     T +ANE+V+ DG + R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VEQKEIPQWFIKITDYAEEllddldqldGWPEQVKAMQRNWIGRSEGVEIDFNVASSEQT  242
            V +K + QW +KIT YA E L +  +  +WPE +K MQRNWIG+S G ++ F+V  +++ 
Sbjct  184  VVRKPMRQWMLKITAYA-ERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LRVYTTRPDTLYGVTYMGVAAQHPLATEAAKTNPELAKFIEECKNSKVAEADIA----TM  298
            + V+TTRPDTL+G TY  +A++H+L    + ++   A  + + K      +D+A    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEA--VADYKRQASLKSDLARTDLAK  300

Query  299  EKLGMDTGIKAVHPMTGEEIPVWVANFVLMDYGSGAVMAVPAHDQRDWEFATKYQLEIRP  358
            EK G+ TG  A++P+ G E+PVW+A++VL  YG+GA+MAVPAHD+RDWEFA +++L+I P
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VIEPLSGDSDIEKAAITEKGTVINSGPYNGMSSAQAFDAIATELKEKGIGERKVNYRLRD  418
            V+E    ++++E AA+TE G  INS+  +G+  A A+  +   L   G+G+ +V YRLRD
Sbjct  361  VLE----GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  419  WGVSRQRYWGTPIPMLNLENGESVPVPEDQLPVKLP--EDVVMDGV-NSPIKSDPEWRK-  474
            W  SRQRYWG PIP+++ E+G S +VPE +LP+ LP   D+   G  +SP+ +  +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  475  TEYNGQPAEHETDTFDTFMESSWYYARYCSAQTDDAMLDPEKANYWLPVDQYIGGIEHAI  534
            T  +G  + +ET+T      SSWYY RY  ++  + + D E  + WLPVD Y+GG EHA+
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  535  LHLLYARFFHKLLRDTGLVESDEPFKRLLCQGMVLADSYYREDEKGGKQWVSPLEVDIER  594
            LHLLYARF HK+L D G+V + EPF++L+ QGM+L+ SY   D +G+        V  ++
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY--RDSRGAL-------VATDK  587

Query  595  DDKGAIAGAKHKQDGQPVNIGGMSKMSKSKNNGIDPQTMVERYGADTVRLFMMFAAPPEM  654
             +K   ++  H + G+ ++ +  +KMSKS +N ++P+ +VE+YGADT+R++ MF +P + 
Sbjct  588  VEKRD-GSFFHVETGEELEQAP-AKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  655  TLEWSDSGVEGAQRFLRRLWKLTYELNNAGGACSGQSLNANQKQLRRELHKTIAKVSDDM  714
            ++ WS+ G+EG+++FL R+ +L           + +  + N   L +  + T+  V++++
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLI---------TTKEITEENSGALDKVYNETVKAVTEQV  696

Query  715  GRRQHFNTAIAAIMELLNHLQKAPLESEADRQVLAESIDATVRMLAPITPHICEQLWQEL  774
            ++ + FNTAIA +M ++N  +K       + +++++   + V+++AP++PH+ E+LWQ L
Sbjct  697  DQMK-FNTAIAQLMVFVNAANK-------EDKLFSDYAKGFVQLIAPFAPHLGEELWQAL  748

Query  775  -GHQEPLSFADWPAVDESALVEDEKLIVVQINGKVRAKLTVPADASAEQVEQIAFDEEAV  833
             +  E++S+  WP+ DES LVE++  IVVQI+GKV+AKL V+ D S E+++++A+ +E V
Sbjct  749  TASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKV  808

Query  834  QKHTEGKDVRKKIYVPGKILNIVV  857
            Q +  GKD+ K I VP K++NIV+
Sbjct  809  QAEIAGKDIIKVIAVPNKLVNIVI  832

895) leuS in NC_006512


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  559 bits (2112),  Expect = 2e-160, Method: Compositional matrix adjust.
 Identities = 360/864 (42%), Positives = 571/864 (67%), Gaps = 46/864 (5%)

Query  5    YNPSKIESAMQKRWQEQDVFTAKEQPGKDKFYCLSMFPYPSGK-LHMGHVRNYTLGDVIS  63
            Y+ + IE+  Q  W +++ F +  +++K KFY L MFPYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RHQRMLGKNVMQPMGWDAFGLPAENAAIQNKTAPAKWTYQNIDYMREQLKSLGFGYDWNR  123
            R +R  G NV++PMGWDAFGLPAE+ A++    PA  T +NI   + Q+++LGF+YDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCSPDYYRWEQWFFTKLYEKGLVYKKNATVNWDPVDQTVLANEQVI-DGRGWRSGAK  182
            E+ T  P+YY+W QW+FTKLYEKGL Y  +  VNW     T +ANE+V+ DG + R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VEQKEIPQWFIKITDYAEEllddldqldGWPEQVKAMQRNWIGRSEGVEIDFNVASSEQT  242
            V +K + QW +KIT YA E L +  +  +WPE +K MQRNWIG+S G ++ F+V  +++ 
Sbjct  184  VVRKPMRQWMLKITAYA-ERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LRVYTTRPDTLYGVTYMGVAAQHPLATEAAKTNPELAKFIEECKNSKVAEADIA----TM  298
            + V+TTRPDTL+G TY  +A++H+L    + ++   A  + + K      +D+A    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEA--VADYKRQASLKSDLARTDLAK  300

Query  299  EKLGMDTGIKAVHPMTGEEIPVWVANFVLMDYGSGAVMAVPAHDQRDWEFATKYQLEIRP  358
            EK G+ TG  A++P+ G E+PVW+A++VL  YG+GA+MAVPAHD+RDWEFA +++L+I P
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VIEPLSGDSDIEKAAITEKGTVINSGPYNGMSSAQAFDAIATELKEKGIGERKVNYRLRD  418
            V+E    ++++E AA+TE G  INS+  +G+  A A+  +   L   G+G+ +V YRLRD
Sbjct  361  VLE----GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  419  WGVSRQRYWGTPIPMLNLENGESVPVPEDQLPVKLP--EDVVMDGV-NSPIKSDPEWRK-  474
            W  SRQRYWG PIP+++ E+G S +VPE +LP+ LP   D+   G  +SP+ +  +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  475  TEYNGQPAEHETDTFDTFMESSWYYARYCSAQTDDAMLDPEKANYWLPVDQYIGGIEHAI  534
            T  +G  + +ET+T      SSWYY RY  ++  + + D E  + WLPVD Y+GG EHA+
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  535  LHLLYARFFHKLLRDTGLVESDEPFKRLLCQGMVLADSYYREDEKGGKQWVSPLEVDIER  594
            LHLLYARF HK+L D G+V + EPF++L+ QGM+L+ SY   D +G+        V  ++
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY--RDSRGAL-------VATDK  587

Query  595  DDKGAIAGAKHKQDGQPVNIGGMSKMSKSKNNGIDPQTMVERYGADTVRLFMMFAAPPEM  654
             +K   ++  H + G+ ++ +  +KMSKS +N ++P+ +VE+YGADT+R++ MF +P + 
Sbjct  588  VEKRD-GSFFHVETGEELEQAP-AKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  655  TLEWSDSGVEGAQRFLRRLWKLTYELNNAGGACSGQSLNANQKQLRRELHKTIAKVSDDM  714
            ++ WS+ G+EG+++FL R+ +L           + +  + N   L +  + T+  V++++
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLI---------TTKEITEENSGALDKVYNETVKAVTEQV  696

Query  715  GRRQHFNTAIAAIMELLNHLQKAPLESEADRQVLAESIDATVRMLAPITPHICEQLWQEL  774
            ++ + FNTAIA +M ++N  +K       + +++++   + V+++AP++PH+ E+LWQ L
Sbjct  697  DQMK-FNTAIAQLMVFVNAANK-------EDKLFSDYAKGFVQLIAPFAPHLGEELWQAL  748

Query  775  -GHQEPLSFADWPAVDESALVEDEKLIVVQINGKVRAKLTVPADASAEQVEQIAFDEEAV  833
             +  E++S+  WP+ DES LVE++  IVVQI+GKV+AKL V+ D S E+++++A+ +E V
Sbjct  749  TASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKV  808

Query  834  QKHTEGKDVRKKIYVPGKILNIVV  857
            Q +  GKD+ K I VP K++NIV+
Sbjct  809  QAEIAGKDIIKVIAVPNKLVNIVI  832

896) Dret_1425 in NC_013223


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  559 bits (2110),  Expect = 3e-160, Method: Compositional matrix adjust.
 Identities = 369/865 (43%), Positives = 547/865 (64%), Gaps = 76/865 (8%)

Query  4    YTPQHIETTWQDAWSRNRDFDTAVDPDKPKYYVLEMFPYPSGR-IHMGHVRVYTIGDVIA  62
            Y    IE  WQ  W+ N+ F T+ D+ KPK+Y L+MFPYPSG  +H+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RFKRMRGYNVFHPMGWDAFGLPAENAAIKHGTHPAKWTYANITEMRQQLQRLGYSLEWQR  122
            RFKR +G NV+HPMGWDAFGLPAE+ A+  G +PA  T  NI++ ++Q++ LG+S +W+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  ELATCHPGYYKWEQLFFLKLYEKGLIYRKKAPVNWCPGCNTVLANEQV-EEGMCWRCDSE  181
            E+ T +P YYKW Q +F KLYEKGL Y    PVNW     T +ANE+V  +G   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VEHKELAQWFVRITAYADELLQDLDKLDGTWPERVITMQRNWIGKSYGSEIDFQVDGLEE  241
            V +K + QW ++ITAYA+ LL+DL+ +D  WPE +  MQRNWIGKS G+++ F+V + + 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD--WPESIKDMQRNWIGKSTGANVTFKVKDTDK  241

Query  242  SIRVFTTRPDTLYGATFMSLAPEHPLVETCIARAEDPEAVRAFVERIRNQDRNIRSIEEQ  301
             + VFTTRPDTL+GAT+  LAPEH+LV++ I+ ++++EAV  +  +   +    R+   +
Sbjct  242  DFTVFTTRPDTLFGATYAVLAPEHALVDA-ITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  302  EKEGIFTGSYCLNPVTGERMPIYVANFVLMEYGTGAVMAVPAHDQRDFEFATKYNLPIRV  361
            EK G+ TGSY +NPV G  MP+ +A++VL  YGTGA+MAVPAHD+RD EFA ++NL I  
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  362  VIQPDNEACLEETTLEQAYTEPGILAQSGPFTGQDNESAKQAITEHLEANGQGTQTVQYR  421
            V++ +N         E A+TE G+  +S+ + G D+ SA   + E LEA+G G + V YR
Sbjct  361  VLEGGNVE-------EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYR  413

Query  422  LRDWNISRQRYWGAPIPMVYCDTCGVQPVPAEDLPVDLPL--EVQTNPDGRSPLPDSEAF  479
            LRDW +SRQRYWG PIP++  +     +VP  +LP+ LP+  +++ +  G SPL++    
Sbjct  414  LRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDW  473

Query  480  VHTTCPQCGGIAQRETDTMDTFVESSWYFARYTASRLESAPFDKEALDYWLPVDQYIGGI  539
            ++ T  + G  ++RET+TM     SSWY+ RY  ++      D E L  WLPVD Y+GG 
Sbjct  474  LEVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGA  532

Query  540  EHAILHLLYARFFTKALRDLGYMDLDEPFQHLLTQGMVL-------------------KD  580
            EHA+LHLLYARF  K L DLG +   EPFQ L+ QGM+L                   +D
Sbjct  533  EHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRD  592

Query  581  G---------------AKMSKSKGNIVDPNEMLETYGADTTRLFTLFAAPPERDLDWNDK  625
            G               AKMSKS  N+V+P++++E YGADT R++ +F +P +  + W++ 
Sbjct  593  GSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEE  652

Query  626  AVEGAYRFLARLWRMGQDLSGtlptlpacaplpaGELSETAAALRRKEHLTVQKVSADME  685
            ++EG+ +FL R+ R+                       E ++AL +  + TV+ V+ +++
Sbjct  653  GLEGSRKFLDRVYRL---------------ITTKEITEENSGALDKVYNETVKAVTEQVD  697

Query  686  EKFQFNTAIAAVMELVNEISAARESLLASETDRHALGSalattltllaPMTPHLCEELWQ  745
            +  +FNTAIA +M +VN  +A +E  L S+  +  +         L+AP +PHL EELWQ
Sbjct  698  QM-KFNTAIAQLMVFVN--AANKEDKLFSDYAKGFV--------QLIAPFAPHLGEELWQ  746

Query  746  RLGHTT-PLAQTGWPTYDPDALRQDEVQIVVQVNGKLRGKIAVATDAAKETIQEAALAHE  804
             L  +  +++   WP+YD   L +++V+IVVQ++GK+++K+ VA D ++E +QE ALA+E
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  805  NVQHHISGKEIKKVIVVPGKLVNVV  829
            +VQ +I+GK+I KVI VP KLVN+V
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIV  831

897) leuS in NC_014550


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  559 bits (2111),  Expect = 3e-160, Method: Compositional matrix adjust.
 Identities = 358/853 (42%), Positives = 556/853 (66%), Gaps = 62/853 (7%)

Query  11   YDFKDIESKWLPVWDELKVFKPADDGSRERRYVLDMFPYPSG-DLHMGHAEAFAMGDVVA  69
            YD   IE+KW + W +   FK + D+S+ + Y LDMFPYPSG +LH+GH+E+++  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  70   RYWRLRGYDVMHPIGWDSFGLPAENAAIKRNAHPAEWTYKNIDTQAASFKRYAISADWDR  129
            R+ R +G +V+HP+GWD+FGLPAE+ A+    +PAE T  NI      ++  ++S DWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  130  RLHTSDPEYYRWTQWLFNKFYDKGLAYRKDHPVNWCPKDQTVLANEQVV-NGACERCGTA  188
             ++T+DP+YY+WTQW+F K+Y+KGLAY  + PVNW     T +ANE+V+ +G+ ER G +
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  189  VTKKSLNQWYFKITDYADRLLEDMDQLKGHWPERVLLMQKNWIGRSEGAEVTFEIEATDA  248
            V +K++ QW +KIT YA+RLLED++++  +WPE +  MQ+NWIG+S GA+VTF +  TD 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV--DWPESIKDMQRNWIGKSTGANVTFKVKDTDK  241

Query  249  KPAVQIPVFTTRPDTLYGATFMVVAADAELAGELVTDEHRGALEEYQEQVKALSEIERQS  308
                ++ VFTTRPDTL+GAT+ V+A++  L + + T ++  A+ +Y+ Q    S++ R  
Sbjct  242  ----DFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTD  297

Query  309  TEREKTGVFTGRYGINPLSGEKLPIWAADYVLADYGTGAIMAVPAHDQRDLDFARAFDLP  368
              +EKTGV TG Y+INP++G  +P+W ADYVLA YGTGAIMAVPAHD+RD +FA+ F+L 
Sbjct  298  LAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLD  357

Query  369  VRVVVDTGEEDPNETGTATAGEGQLVNSGELTGLeksaaiakaieiveaaGTGKHTINFR  428
            +  V++ G+ +     +A + +G  +NS+ L GL+K++AIAK +E +EA G G++ + +R
Sbjct  358  IIPVLEGGNVE----EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYR  413

Query  429  LRDWLLSRQRFWGTPIPIIHCADCGEVPVPDDQLPVRLPDNLRGEQLAPKGTSPLAAAEE  488
            LRDWL+SRQR+WG PIPIIH  D    +VP+ +LP+ LP   ++ + +  G SPLA   +
Sbjct  414  LRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVT-KDIRPSGTGESPLANVTD  472

Query  489  WVNVACPKCGADAKRDTDTMDTFVDSSWYFLRFVSPDYTEGPFDPKAVRDWMPVGQYVGG  548
            W++V+    G  ++R+T+TM    +SSWY+LR++ P+ TE   D   +++W+PV+ YVGG
Sbjct  473  WLEVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGG  531

Query  549  VEHAILHLLYSRFFTKVIHDLGLIDATEPFSALLNQGQVLNGG-----------------  591
             EHA+LHLLY+RF  KV+ DLG++ + EPF  L+NQG +L  +                 
Sbjct  532  AEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKR  591

Query  592  -----------------KAMSKSLGNGVDLGEQLDKFGVDAVRLTMIFASPPEDDVDWAD  634
                               MSKSL N V+ ++ ++++G D++R+  +F +P +  + W++
Sbjct  592  DGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSE  651

Query  635  VSPSGSQKFLARAWRIAQDTTSEAGADYAAGDKALRQVTHRTVHESAQLLDSGKFNVVIA  694
             +  GS+KFL R  R+   TT E   + ++   AL +V + TV   ++ +D  KFN  IA
Sbjct  652  EGLEGSRKFLDRVYRLI--TTKEITEENSG---ALDKVYNETVKAVTEQVDQMKFNTAIA  706

Query  695  KTMELVNATRKTIDSGAGATDPAVREAATVVAQLLSMFAPYTAEDMWEALGYAPSVVT-S  753
            + M +VNA+ K         D    + A    QL++ FAP  +E++W+AL  +   ++  
Sbjct  707  QLMVFVNAANK--------EDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYV  758

Query  754  AWPEVDESLLVDDTITAVVQIKGKVRARLEVSVDITEDELREQALAHESVIRMLDGKEPL  813
            +WP  DES LV++ +  VVQIKGKV+A+L V+ D++ +EL+E ALA+E V   + GK+ +
Sbjct  759  PWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDII  818

Query  814  KVIVRAPKLVNVV  826
            KVI  + KLVN+V
Sbjct  819  KVIAVPNKLVNIV  831

898) leuS in NC_003030


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  559 bits (2109),  Expect = 4e-160, Method: Compositional matrix adjust.
 Identities = 383/846 (46%), Positives = 549/846 (65%), Gaps = 58/846 (6%)

Query  6    TKVDEKWQKKWEETSLYKFDENNLEKKLYVLEMFSYPSGAKLHAGHWFNYAPVDSWARFK  65
            T ++ KWQ  W +   +K + +    K+Y L+MF+YPSGA LH GH   Y++ D  +RFK
Sbjct  7    TAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSRFK  66

Query  66   KMTGYNVFQPMGFDAFGLPAENYAIKTGIHPKDSTLKNIETMEKQLKSMGAMFNWDHEVI  125
            +  G NV++PMG DAFGLPAE+YA+ TG +P + T  NI    +Q++++G  ++WD+EV 
Sbjct  67   RAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDREVN  126

Query  126  TCTPDYYKWTQWLFLELYKNGLAYRKKAPANWCPSCNTVLANEQVV-DGSCERCGTEVIK  184
            T  P+YYKWTQW+F  LY +GLAY    P NW     T +ANE+V+ DG+ ER G  V++
Sbjct  127  TTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVR  186

Query  185  KDLTQWFFKITNYAEELLQKLDELDWPEKTKAMQKHWIGKSKGAEVTFKVDNSDLKFDVF  244
            K + QW +KIT YAE LL+ L+E+DWPE  K MQ++WIGKS GA+VTFKV ++D  F VF
Sbjct  187  KPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVF  246

Query  245  TTRVDTLCGVTYVVLAPESPLADELTkpeykekveeykLQAQKQSEIERQSLTREKTGVF  304
            TTR DTL G TY VLAPE +L D +T ++  E V +YK QA  +S++ R  L++EKTGV 
Sbjct  247  TTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVW  306

Query  305  TGSYAINPINNKKVPIWIADYVIYTYGTGAVMAVPSHDERDFAFATKYDLPIVRVVEGG-  363
            TGSYAINP+N K +P+WIADYV+ +YGTGA+MAVP+HDERD  FA +++L I+ V+EGG 
Sbjct  307  TGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGN  366

Query  364  -EELPFTGYGPLVNSGEFDGLKGNKAKEAIVSKLSENDLGRWKVNYRLRDWLVSRQRYWG  422
             EE +FT  G  +NS+ +DGL    A   +V  L  +++G  +V YRLRDWL SRQRYWG
Sbjct  367  VEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWG  426

Query  423  APIPVVYCEKCGIVPVPEKDLPVELPYNVEFNP--TGKSPLTTSEEFMNTTCPHCGGHAT  480
             PIP++  E     +VPE +LP+ LP   ++ P  TG SPL+   + ++ T  + G  + 
Sbjct  427  EPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED-GVKGR  485

Query  481  RESDTLDTFVCSSWYYLRYADNENSDAPFDKEKISKMLPVDKYVGGPEHACMHLLYARFI  540
            RE++T+     SSWYYLRY D +N++   D E + + LPVD YVGG+EHA +HLLYARF 
Sbjct  486  RETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFW  545

Query  541  TKALRDIGYLNFDEPFLSLRHQGLILGP--------------------------------  568
             K L D+G +   EPF  L +QG+ILG                                 
Sbjct  546  HKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEELE  605

Query  569  -DGQKMSKSKGNTISPDDIIAEHGSDVFRMYLMFGFDYAEGGAWSDDGVKAMSKFVDRFS  627
                KMSKS  N ++PDD++ + G+D +R+Y MF      + AWS++G+ +  KF+DR  
Sbjct  606  QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVY  665

Query  628  RMIETAKEEINNPKNSKTDMGKEEKELNYVRNHSIKAVTEDMDKFQFNTCIARLMEFTNS  687
            R+I T   EI + +++          L+ V N+++KAVTE++D+ +FNT IA+LM F N+
Sbjct  666  RLITT--KEITEENSG---------ALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNA  714

Query  688  LSKYLTVDNKNIKLLKDTTIDIIKLIAPFAPHFAEEQWNIIEEKYSVFN-EKWPEFDEKA  746
                    NK+ KL+ D + ++++LIAPFAPH++EE W+ +      ++   WP +DE  
Sbjct  715  -------ANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESK  767

Query  747  LVKDEVEiaiqingkikakiniatnLSEDEIKSAALADDKVKAATDGKNIVKVIVIKGRL  806
            LV ++VEI +QI+GK+KAK+ +A +LS +E++  ALA++KV+A   GK+I+KVI +  +L
Sbjct  768  LVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKL  827

Query  807  VNIVVK  812
            VNIV+K
Sbjct  828  VNIVIK  833

899) leuS in NC_015687


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  559 bits (2109),  Expect = 4e-160, Method: Compositional matrix adjust.
 Identities = 383/846 (46%), Positives = 549/846 (65%), Gaps = 58/846 (6%)

Query  6    TKVDEKWQKKWEETSLYKFDENNLEKKLYVLEMFSYPSGAKLHAGHWFNYAPVDSWARFK  65
            T ++ KWQ  W +   +K + +    K+Y L+MF+YPSGA LH GH   Y++ D  +RFK
Sbjct  7    TAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSRFK  66

Query  66   KMTGYNVFQPMGFDAFGLPAENYAIKTGIHPKDSTLKNIETMEKQLKSMGAMFNWDHEVI  125
            +  G NV++PMG DAFGLPAE+YA+ TG +P + T  NI    +Q++++G  ++WD+EV 
Sbjct  67   RAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDREVN  126

Query  126  TCTPDYYKWTQWLFLELYKNGLAYRKKAPANWCPSCNTVLANEQVV-DGSCERCGTEVIK  184
            T  P+YYKWTQW+F  LY +GLAY    P NW     T +ANE+V+ DG+ ER G  V++
Sbjct  127  TTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVR  186

Query  185  KDLTQWFFKITNYAEELLQKLDELDWPEKTKAMQKHWIGKSKGAEVTFKVDNSDLKFDVF  244
            K + QW +KIT YAE LL+ L+E+DWPE  K MQ++WIGKS GA+VTFKV ++D  F VF
Sbjct  187  KPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVF  246

Query  245  TTRVDTLCGVTYVVLAPESPLADELTkpeykekveeykLQAQKQSEIERQSLTREKTGVF  304
            TTR DTL G TY VLAPE +L D +T ++  E V +YK QA  +S++ R  L++EKTGV 
Sbjct  247  TTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVW  306

Query  305  TGSYAINPINNKKVPIWIADYVIYTYGTGAVMAVPSHDERDFAFATKYDLPIVRVVEGG-  363
            TGSYAINP+N K +P+WIADYV+ +YGTGA+MAVP+HDERD  FA +++L I+ V+EGG 
Sbjct  307  TGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGN  366

Query  364  -EELPFTGYGPLVNSGEFDGLKGNKAKEAIVSKLSENDLGRWKVNYRLRDWLVSRQRYWG  422
             EE +FT  G  +NS+ +DGL    A   +V  L  +++G  +V YRLRDWL SRQRYWG
Sbjct  367  VEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWG  426

Query  423  APIPVVYCEKCGIVPVPEKDLPVELPYNVEFNP--TGKSPLTTSEEFMNTTCPHCGGHAT  480
             PIP++  E     +VPE +LP+ LP   ++ P  TG SPL+   + ++ T  + G  + 
Sbjct  427  EPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED-GVKGR  485

Query  481  RESDTLDTFVCSSWYYLRYADNENSDAPFDKEKISKMLPVDKYVGGPEHACMHLLYARFI  540
            RE++T+     SSWYYLRY D +N++   D E + + LPVD YVGG+EHA +HLLYARF 
Sbjct  486  RETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFW  545

Query  541  TKALRDIGYLNFDEPFLSLRHQGLILGP--------------------------------  568
             K L D+G +   EPF  L +QG+ILG                                 
Sbjct  546  HKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEELE  605

Query  569  -DGQKMSKSKGNTISPDDIIAEHGSDVFRMYLMFGFDYAEGGAWSDDGVKAMSKFVDRFS  627
                KMSKS  N ++PDD++ + G+D +R+Y MF      + AWS++G+ +  KF+DR  
Sbjct  606  QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVY  665

Query  628  RMIETAKEEINNPKNSKTDMGKEEKELNYVRNHSIKAVTEDMDKFQFNTCIARLMEFTNS  687
            R+I T   EI + +++          L+ V N+++KAVTE++D+ +FNT IA+LM F N+
Sbjct  666  RLITT--KEITEENSG---------ALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNA  714

Query  688  LSKYLTVDNKNIKLLKDTTIDIIKLIAPFAPHFAEEQWNIIEEKYSVFN-EKWPEFDEKA  746
                    NK+ KL+ D + ++++LIAPFAPH++EE W+ +      ++   WP +DE  
Sbjct  715  -------ANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESK  767

Query  747  LVKDEVEiaiqingkikakiniatnLSEDEIKSAALADDKVKAATDGKNIVKVIVIKGRL  806
            LV ++VEI +QI+GK+KAK+ +A +LS +E++  ALA++KV+A   GK+I+KVI +  +L
Sbjct  768  LVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKL  827

Query  807  VNIVVK  812
            VNIV+K
Sbjct  828  VNIVIK  833

900) leuS in NC_017295


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  559 bits (2109),  Expect = 4e-160, Method: Compositional matrix adjust.
 Identities = 383/846 (46%), Positives = 549/846 (65%), Gaps = 58/846 (6%)

Query  6    TKVDEKWQKKWEETSLYKFDENNLEKKLYVLEMFSYPSGAKLHAGHWFNYAPVDSWARFK  65
            T ++ KWQ  W +   +K + +    K+Y L+MF+YPSGA LH GH   Y++ D  +RFK
Sbjct  7    TAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSRFK  66

Query  66   KMTGYNVFQPMGFDAFGLPAENYAIKTGIHPKDSTLKNIETMEKQLKSMGAMFNWDHEVI  125
            +  G NV++PMG DAFGLPAE+YA+ TG +P + T  NI    +Q++++G  ++WD+EV 
Sbjct  67   RAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDREVN  126

Query  126  TCTPDYYKWTQWLFLELYKNGLAYRKKAPANWCPSCNTVLANEQVV-DGSCERCGTEVIK  184
            T  P+YYKWTQW+F  LY +GLAY    P NW     T +ANE+V+ DG+ ER G  V++
Sbjct  127  TTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVR  186

Query  185  KDLTQWFFKITNYAEELLQKLDELDWPEKTKAMQKHWIGKSKGAEVTFKVDNSDLKFDVF  244
            K + QW +KIT YAE LL+ L+E+DWPE  K MQ++WIGKS GA+VTFKV ++D  F VF
Sbjct  187  KPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVF  246

Query  245  TTRVDTLCGVTYVVLAPESPLADELTkpeykekveeykLQAQKQSEIERQSLTREKTGVF  304
            TTR DTL G TY VLAPE +L D +T ++  E V +YK QA  +S++ R  L++EKTGV 
Sbjct  247  TTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVW  306

Query  305  TGSYAINPINNKKVPIWIADYVIYTYGTGAVMAVPSHDERDFAFATKYDLPIVRVVEGG-  363
            TGSYAINP+N K +P+WIADYV+ +YGTGA+MAVP+HDERD  FA +++L I+ V+EGG 
Sbjct  307  TGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGN  366

Query  364  -EELPFTGYGPLVNSGEFDGLKGNKAKEAIVSKLSENDLGRWKVNYRLRDWLVSRQRYWG  422
             EE +FT  G  +NS+ +DGL    A   +V  L  +++G  +V YRLRDWL SRQRYWG
Sbjct  367  VEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWG  426

Query  423  APIPVVYCEKCGIVPVPEKDLPVELPYNVEFNP--TGKSPLTTSEEFMNTTCPHCGGHAT  480
             PIP++  E     +VPE +LP+ LP   ++ P  TG SPL+   + ++ T  + G  + 
Sbjct  427  EPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED-GVKGR  485

Query  481  RESDTLDTFVCSSWYYLRYADNENSDAPFDKEKISKMLPVDKYVGGPEHACMHLLYARFI  540
            RE++T+     SSWYYLRY D +N++   D E + + LPVD YVGG+EHA +HLLYARF 
Sbjct  486  RETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFW  545

Query  541  TKALRDIGYLNFDEPFLSLRHQGLILGP--------------------------------  568
             K L D+G +   EPF  L +QG+ILG                                 
Sbjct  546  HKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEELE  605

Query  569  -DGQKMSKSKGNTISPDDIIAEHGSDVFRMYLMFGFDYAEGGAWSDDGVKAMSKFVDRFS  627
                KMSKS  N ++PDD++ + G+D +R+Y MF      + AWS++G+ +  KF+DR  
Sbjct  606  QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVY  665

Query  628  RMIETAKEEINNPKNSKTDMGKEEKELNYVRNHSIKAVTEDMDKFQFNTCIARLMEFTNS  687
            R+I T   EI + +++          L+ V N+++KAVTE++D+ +FNT IA+LM F N+
Sbjct  666  RLITT--KEITEENSG---------ALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNA  714

Query  688  LSKYLTVDNKNIKLLKDTTIDIIKLIAPFAPHFAEEQWNIIEEKYSVFN-EKWPEFDEKA  746
                    NK+ KL+ D + ++++LIAPFAPH++EE W+ +      ++   WP +DE  
Sbjct  715  -------ANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESK  767

Query  747  LVKDEVEiaiqingkikakiniatnLSEDEIKSAALADDKVKAATDGKNIVKVIVIKGRL  806
            LV ++VEI +QI+GK+KAK+ +A +LS +E++  ALA++KV+A   GK+I+KVI +  +L
Sbjct  768  LVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKL  827

Query  807  VNIVVK  812
            VNIV+K
Sbjct  828  VNIVIK  833

901) leuS in NC_022269


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  559 bits (2109),  Expect = 4e-160, Method: Compositional matrix adjust.
 Identities = 376/871 (44%), Positives = 569/871 (66%), Gaps = 54/871 (6%)

Query  5    YNPQDLEQKVQKHWDDNKTFVVSEDPNKEKFYCLSMFPYPSGR-LHMGHVRNYTIGDVVS  63
            Y+   +E K Q  W DN TF  + D++K KFY L MFPYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RFQRLQGKNVMQPIGWDAFGLPAENAAVKNNTAPAPWTYENIEYMKNQLKLLGFGYDWNR  123
            RF+R QG NV++P+GWDAFGLPAE+ A+     PA  T ENI   K Q++ LGF+YDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EFATCTPEYYRWEQEFFTKLYEKGLVYKKTSSVNWCPNDQTVLANEQV-EDGCCWRCDTP  182
            E  T  P+YY+W Q +FTKLYEKGL Y    +VNW  +  T +ANE+V  DG   R + P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VEQKEIPQWFIKITEYAQELLDDLDKLEGWPEMVKTMQRNWIGRSEGVELRFALKDSEVK  242
            V +K + QW +KIT YA+ LL+DL+ ++ WPE +K MQRNWIG+S G ++ F +KD++  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTD--  240

Query  243  GQQDLEVYTTRPDTLMGVTYVGIAAGHPL--ATIAAENNPELAAFI-EECKNTKVAEAEL  299
              +D+ V+TTRPDTL G TY  +A+ H+L  A  ++++   +A +  +   ++ +A ++L
Sbjct  241  --KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDL  298

Query  300  ATMEKKGMATGLTAIHPLNGREVPVYVANFVLMDYGTGAVMAVPAHDQRDFEFATKYGLD  359
            A  EK G+ TG  AI+P+NG+E+PV +A++VL  YGTGA+MAVPAHD+RD EFA ++ LD
Sbjct  299  A-KEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLD  357

Query  360  IVPVIKPVDGSELDTSEAAYTEKGVLFDSGEFDGLEFQAAFDAIAAKLEAEGKGTKTVNF  419
            I+PV+   +G++++  EAA+TE G+ ++S+ +DGL+  +A+  +   LEAEG G   V +
Sbjct  358  IIPVL---EGGNVE--EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTY  412

Query  420  RLRDWGVSRQRYWGAPIPMVTTEDGEVHPVPADQLPVILP--EDVVMDGVT-SPIKADKE  476
            RLRDW  SRQRYWG PIP++  EDG   +VP  +LP++LP   D+   G   SP+    +
Sbjct  413  RLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTD  472

Query  477  WAKTTF-NGEPALRETDTFDTFMESSWYYARYCSPQADDILAPEK-ANYWLPVDQYIGGI  534
            W   T  +G  + RET+T      SSWYY RY  P+  + LA E   + WLPVD Y+GG 
Sbjct  473  WLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGA  532

Query  535  EHACMHLLYSRFFHKLLRDAGYVTSDEPFKQLLCQGMVLADAFYFENEKGGKEWVAPTDV  594
            EHA +HLLY+RF HK+L D G V + EPF++L+ QGM+L+ +  + + +G+   + +TD 
Sbjct  533  EHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS--YRDSRGA---LVATDK  587

Query  595  AVERDGK-GRITSAKDTEGRDVTHSGMIKMSKSKNNGIDPQEMVDKYGADTVRLFMMFAS  653
               RDG   ++ ++ + E       +  KMSKS +N ++P+++V++YGADT+R++ MF +
Sbjct  588  VEKRDGSFFHVETGEELE------QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMG  641

Query  654  PADMTLEWQESGVEGANRFLKRVWKLVNEHTSKGAAEAVDAAALSGDQKALRRDVHKTIA  713
            P D ++ W E G+EG+ +FL RV +L+   T+K  +E         +  AL +  + T+ 
Sbjct  642  PLDASIAWSEEGLEGSRKFLDRVYRLI---TTKEITEE--------NSGALDKVYNETVK  690

Query  714  KVTDDIDRRQTFNTAIAAIMELMNKLAKAPQESAQDRVILDEALKAVVAMLYPITPHISY  773
             VT+++D+ + FNTAIA +M ++N   K  +       ++ +  K+ V ++ P++PH++ 
Sbjct  691  AVTEQVDQMK-FNTAIAQLMVFVNAANKEDK-------LFSDYAKGFVQLIAPFAPHLGE  742

Query  774  ELWAALGEAD--IDNAAWPTFDEKALVEDEKTIVVQVNGKLRAKLTVAADATKEQVEELG  831
            ELW AL  ++  I   +WP++DE  LVE++  IVVQ++GK++AKL VA D ++E+++E++
Sbjct  743  ELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVA  802

Query  832  LNDENVTKFTDGLTIRKVIYVPGKLLNIVAN  862
            L +E+V     G  I KVI VP KL+NIV +
Sbjct  803  LANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

902) leuS in NC_009783


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  559 bits (2109),  Expect = 4e-160, Method: Compositional matrix adjust.
 Identities = 376/871 (44%), Positives = 569/871 (66%), Gaps = 54/871 (6%)

Query  5    YNPQDLEQKVQKHWDDNKTFVVSEDPNKEKFYCLSMFPYPSGR-LHMGHVRNYTIGDVVS  63
            Y+   +E K Q  W DN TF  + D++K KFY L MFPYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RFQRLQGKNVMQPIGWDAFGLPAENAAVKNNTAPAPWTYENIEYMKNQLKLLGFGYDWNR  123
            RF+R QG NV++P+GWDAFGLPAE+ A+     PA  T ENI   K Q++ LGF+YDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EFATCTPEYYRWEQEFFTKLYEKGLVYKKTSSVNWCPNDQTVLANEQV-EDGCCWRCDTP  182
            E  T  P+YY+W Q +FTKLYEKGL Y    +VNW  +  T +ANE+V  DG   R + P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VEQKEIPQWFIKITEYAQELLDDLDKLEGWPEMVKTMQRNWIGRSEGVELRFALKDSEVK  242
            V +K + QW +KIT YA+ LL+DL+ ++ WPE +K MQRNWIG+S G ++ F +KD++  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTD--  240

Query  243  GQQDLEVYTTRPDTLMGVTYVGIAAGHPL--ATIAAENNPELAAFI-EECKNTKVAEAEL  299
              +D+ V+TTRPDTL G TY  +A+ H+L  A  ++++   +A +  +   ++ +A ++L
Sbjct  241  --KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDL  298

Query  300  ATMEKKGMATGLTAIHPLNGREVPVYVANFVLMDYGTGAVMAVPAHDQRDFEFATKYGLD  359
            A  EK G+ TG  AI+P+NG+E+PV +A++VL  YGTGA+MAVPAHD+RD EFA ++ LD
Sbjct  299  A-KEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLD  357

Query  360  IVPVIKPVDGSELDTSEAAYTEKGVLFDSGEFDGLEFQAAFDAIAAKLEAEGKGTKTVNF  419
            I+PV+   +G++++  EAA+TE G+ ++S+ +DGL+  +A+  +   LEAEG G   V +
Sbjct  358  IIPVL---EGGNVE--EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTY  412

Query  420  RLRDWGVSRQRYWGAPIPMVTTEDGEVHPVPADQLPVILP--EDVVMDGVT-SPIKADKE  476
            RLRDW  SRQRYWG PIP++  EDG   +VP  +LP++LP   D+   G   SP+    +
Sbjct  413  RLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTD  472

Query  477  WAKTTF-NGEPALRETDTFDTFMESSWYYARYCSPQADDILAPEK-ANYWLPVDQYIGGI  534
            W   T  +G  + RET+T      SSWYY RY  P+  + LA E   + WLPVD Y+GG 
Sbjct  473  WLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGA  532

Query  535  EHACMHLLYSRFFHKLLRDAGYVTSDEPFKQLLCQGMVLADAFYFENEKGGKEWVAPTDV  594
            EHA +HLLY+RF HK+L D G V + EPF++L+ QGM+L+ +  + + +G+   + +TD 
Sbjct  533  EHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS--YRDSRGA---LVATDK  587

Query  595  AVERDGK-GRITSAKDTEGRDVTHSGMIKMSKSKNNGIDPQEMVDKYGADTVRLFMMFAS  653
               RDG   ++ ++ + E       +  KMSKS +N ++P+++V++YGADT+R++ MF +
Sbjct  588  VEKRDGSFFHVETGEELE------QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMG  641

Query  654  PADMTLEWQESGVEGANRFLKRVWKLVNEHTSKGAAEAVDAAALSGDQKALRRDVHKTIA  713
            P D ++ W E G+EG+ +FL RV +L+   T+K  +E         +  AL +  + T+ 
Sbjct  642  PLDASIAWSEEGLEGSRKFLDRVYRLI---TTKEITEE--------NSGALDKVYNETVK  690

Query  714  KVTDDIDRRQTFNTAIAAIMELMNKLAKAPQESAQDRVILDEALKAVVAMLYPITPHISY  773
             VT+++D+ + FNTAIA +M ++N   K  +       ++ +  K+ V ++ P++PH++ 
Sbjct  691  AVTEQVDQMK-FNTAIAQLMVFVNAANKEDK-------LFSDYAKGFVQLIAPFAPHLGE  742

Query  774  ELWAALGEAD--IDNAAWPTFDEKALVEDEKTIVVQVNGKLRAKLTVAADATKEQVEELG  831
            ELW AL  ++  I   +WP++DE  LVE++  IVVQ++GK++AKL VA D ++E+++E++
Sbjct  743  ELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVA  802

Query  832  LNDENVTKFTDGLTIRKVIYVPGKLLNIVAN  862
            L +E+V     G  I KVI VP KL+NIV +
Sbjct  803  LANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

903) leuS in NC_014643


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  559 bits (2109),  Expect = 4e-160, Method: Compositional matrix adjust.
 Identities = 363/855 (43%), Positives = 541/855 (64%), Gaps = 63/855 (7%)

Query  14   YDFRAQEAKWRPYWEETGVFKPTGNAAKGRRYVLDMFPYPSG-DLHMGHAEAFAIGDMNA  72
            YD  A E+KW+++W +   FK   +A+K + Y LDMFPYPSG +LH+GH+E+++  D+ +
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  73   RYYKQCGYDVLHPIGWDSFGLPAENAAIKNGTHPKEWTYKNIDTQAESFKRYAIAVDWDR  132
            R+ +  G +VLHP+GWD+FGLPAE+ A+  G +P E T  NI      ++  +++ DWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  133  RLHTSDPEYYKWTQWLFEQFYKQGLAYRKDSMVNWCPKDQTVLANEQVV-NGACERCGTT  191
             ++T+DP+YYKWTQW+F ++Y +GLAY  +  VNW     T +ANE+V+ +G+ ER G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  192  VTKKSLNQWYFKITDYAQQLLDDMEQLEGKWPERVLLMQRNWIGRSEGAEVRFEIEATEA  251
            V +K++ QW +KIT YA++LL+D+E+++  WPE +  MQRNWIG+S GA+V F +  T+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD--WPESIKDMQRNWIGKSTGANVTFKVKDTDK  241

Query  252  QPAESFTVFTTRPDTLYGSTFIVVAADSTFAEQIVAPDQAQALEDYREQIKALSDIDRQS  311
            +    FTVFTTRPDTL+G+T+ V+A++ ++ + I ++DQA+A+ DY+ Q    SD+ R  
Sbjct  242  D----FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTD  297

Query  312  SEREKTGMFTGRYAINPLNGAKLPVWASDYVLADYGTGAIMAVPAHDQRDLDFAKKFDLP  371
              +EKTG+ TG YAINP+NG  +PVW +DYVLA YGTGAIMAVPAHD+RD +FAK+F+L 
Sbjct  298  LAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLD  357

Query  372  IVTVLDVEGEEDPAESGIATAGDGVLINSGELTGLPKAEAIAKATELVEAAGTGEGKVIY  431
            I+ VL+    E++     A + DG+ INS+ L GL KA AIAK  E +EA G G+ +V Y
Sbjct  358  IIPVLEGGNVEEA-----AFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTY  412

Query  432  RLRDWLLSRQRFWGTPIPVIHCEDCGevlvpeeqlpvllpDNLRGEQLAPKGQSPLAAAD  491
            RLRDWL+SRQR+WG PIP+IH ED G      E    L+    ++ + +  G+SPLA   
Sbjct  413  RLRDWLFSRQRYWGEPIPIIHWED-GTSTAVPESELPLVLPVTKDIRPSGTGESPLANVT  471

Query  492  DWAIVPCPQCGKSARRDSDTMDTFVDSSWYFLRYVSPRYAEGPFDPQAIREWGAVDMYVG  551
            DW  V   +  K +RR+++TM    +SSWY+LRY+ P+ +E   D + +++W +VD+YVG
Sbjct  472  DWLEVTREDGVK-GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVG  530

Query  552  GVEHAILHLLYARFFTKVIRDLGLIEHGEPFKALMNQGQVLNGG----------------  595
            G EHA+LHLLYARF  KV+ DLG++   EPF+ L NQG +L  +                
Sbjct  531  GAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEK  590

Query  596  ------------------KAMSKSLGNGVNLGEQLDTFGVDAVRTTMIFASPPEDDVDWA  637
                                MSKSL N VN ++ ++ +G D++R   +F +P +  + W+
Sbjct  591  RDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWS  650

Query  638  DVSPAGSQKFLARAWRVAQDVTSEPGVDAASGDANLHKLVARTVHDVKQLLDSGKFNVVV  697
            + +  GS+KFL R  R+   +T+    +  SG   L+K+   TV  V + +D  KFN  +
Sbjct  651  EEGLEGSRKFLDRVYRL---ITTKEITEENSG--ALDKVYNETVKAVTEQVDQMKFNTAI  705

Query  698  AKTMELVNATRKAVDSGSGGADPAVREATETIAILLSLYAPYTAEDMWHALGHDNPVLT-  756
            A+ M +VNA+ K         D    + +  +  L++ +AP  +E++W+AL      ++ 
Sbjct  706  AQLMVFVNAANK--------EDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISY  757

Query  757  AGFPQVDESLLVDDTVTAIVQIKGKVKARLEVSKDISEAELEKQALEDETIAKLVEGSEI  816
               P  DES LV++ V  +VQIKGKVKA+L V+KD+S  EL+  AL +E +   + G +I
Sbjct  758  VPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDI  817

Query  817  RRVIVRAPKLVNIVI  831
             +VI  + KLVNIVI
Sbjct  818  IKVIAVPNKLVNIVI  832

904) vfu_A02646 in NC_016602


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  558 bits (2108),  Expect = 4e-160, Method: Compositional matrix adjust.
 Identities = 376/867 (44%), Positives = 563/867 (65%), Gaps = 50/867 (5%)

Query  5    YNPQDIEQKVQEHWESNKTFVVSEDPNKEKFYCLSMFPYPSGR-LHMGHVRNYTIGDVVA  63
            Y+   IE K Q  W  N TF  + D++K KFY L MFPYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RFQRLQGKNVMQPIGWDAFGLPAENAAVKNNTAPAPWTYENIEYMKNQLKLLGFGYDWNR  123
            RF+R QG NV++P+GWDAFGLPAE+ A+     PA  T ENI   K Q++ LGF+YDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EFATCRPEYYRWEQEFFTKLYEKGLVYKKTSSVNWCPNDQTVLANEQV-EDGCCWRCDTP  182
            E  T  P+YY+W Q +FTKLYEKGL Y    +VNW  +  T +ANE+V  DG   R + P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VEQKEIPQWFIKITAYAQELLDDLDNLDGWPEMVKTMQRNWIGRSEGVELKFAVKDHAQD  242
            V +K + QW +KITAYA+ LL+DL+++D WPE +K MQRNWIG+S G ++ F VKD  +D
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LEVYTTRPDTLMGVTYVGIAAGHPLATEAAKSNPALAAFIDECKNTKVAEAELA----TM  298
            + V+TTRPDTL G TY  +A+ H+L    + S+ A A  + + K      ++LA    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEA--VADYKRQASLKSDLARTDLAK  300

Query  299  EKKGMATGLTAIHPLNGREVPIFVANFVLMDYGTGAVMAVPAHDQRDFEFATKYNLDIIP  358
            EK G+ TG  AI+P+NG+E+P+ +A++VL  YGTGA+MAVPAHD+RD EFA ++NLDIIP
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VIKPLDGSELDISEAAYTEKGVLFDSGEFDGLEFQAAFDAIAAKLEAEGKGVKTVNFRLR  418
            V   L+G++++  EAA+TE G+ ++S+ +DGL+  +A+  +   LEAEG G   V +RLR
Sbjct  361  V---LEGGNVE--EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  419  DWGVSRQRYWGAPIPMVTTEDGVVHPVPADQLPVILP--EDVVMDGVT-SPIKADKAWAE  475
            DW  SRQRYWG PIP++  EDG   +VP  +LP++LP   D+   G   SP+     W E
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  476  TTF-NGEPALRETDTFDTFMESSWYYARYCSPQADDIL-DPEKANYWLPVDQYIGGIEHA  533
             T  +G  + RET+T      SSWYY RY  P+  + L D E  + WLPVD Y+GG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  534  CMHLLYSRFFHKLLRDAGYVTSDEPFKQLLCQGMVLADAFYYTNDKGGKEWVSPTEVKVE  593
             +HLLY+RF HK+L D G V + EPF++L+ QGM+L+ +  Y + +G+   + +T+ KVE
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS--YRDSRGA---LVATD-KVE  589

Query  594  RDGKGRITTAVDSHGRSVEHSGMIKMSKSKNNGIDPQEMVDKYGADTVRLFMMFASPADM  653
            + + + +       G  +E++   KMSKS +N ++P+++V++YGADT+R++ MF +P D 
Sbjct  590  KRDGSFFHVET---GEELEQAP-AKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  654  TLEWQESGVEGANRFLKRVWKLVREHTEKGEATAVDTAALTGDQKALRRDVHKTIAKVTD  713
            ++ W E G+EG+ +FL RV +L+       E ++           AL +  + T+  VT+
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLITTKEITEENSG-----------ALDKVYNETVKAVTE  694

Query  714  DIARRQTFNTAIAAVMELMNKLGKAPQDDAQDRAILDEALKAITVMLYPIAPHICFEMWN  773
            ++ + + FNTAIA +M ++N   K       +  ++ +  K++  ++ P+APH+  E+W+
Sbjct  695  QVDQMK-FNTAIAQLMVFVNAANK-------EDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  774  ALGQA--NIDSASWPMFDEAALVEDEKLIVLQVNGKLRGKLTVAADATKEQVEALGLSDE  831
            AL  +  +I   +WP +DE+ LVE++  IV+Q++GK+++KL VA D ++E+++ ++L++E
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  832  NVLKFTDGLTIRKVIYVPGKLLNIVAN  858
            +V     G  I KVI VP KL+NIV +
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVIK  833

905) leuS in NC_008740


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  558 bits (2108),  Expect = 4e-160, Method: Compositional matrix adjust.
 Identities = 359/867 (42%), Positives = 558/867 (65%), Gaps = 47/867 (5%)

Query  8    YNPREVEQTARTFWETNETFKVKEEPGKPKYYCLSMFPYPSGK-LHMGHVRNYTIGDVIS  66
            Y+   +E   ++FW  N+TFK   +++KPK+Y L MFPYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  67   RYQRMQGKNVMQPMGWDAFGLPAENAAIANKSAPAKWTRSNIDYMKNQLKQLGFGYDWSR  126
            R++R QG NV++PMGWDAFGLPAE+ A+   + PA  T  NI   K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  127  ELATCDPEYYRWEQWFFARLYEKGLVYKKMSTVNWDPVDQTVLANEQVV-DGRGWRSGAL  185
            E+ T DP+YY+W QW+F++LYEKGL Y     VNW     T +ANE+V+ DG + R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  186  VEQKKIPQWFIRITDYAEELLNDLEDMEGWPEQVKTMQRNWIGKSVGTELTFPLKEQEGG  245
            V +K + QW ++IT YAE LL+DLE+++ WPE +K MQRNWIGKS G+++TF +K+ + +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  246  LTVYTTRPDTLMGVSY--MavaaehplakaaaERHRDVAEFVDQCR-NSKVAEAELATME  302
            +TV+TTRPDTL G +Y  +A       A +++++   VA++  Q   +S +A ++LA  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  303  KKGIDTGFKAIHPLTQEEIPVWVANFVLMDYGTGALMAVPGHDERDHEFAVKYKLPIKQV  362
            K G+ TG  AI+P+   E+PVW+A++VL  YGTGA+MAVP+HDERD EFA +++L I  V
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  363  IAPNDSRDIDIQEQAFTEKGVLVSSGKYSGLTSEEAFEEIADYLEAQGIGKRTVNYRLRD  422
            +        +++E AFTE G+ ++S+   GL    A+  + + LEA+G+G+  V YRLRD
Sbjct  362  LEGG-----NVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  423  WGVSRQRYWGAPIPMMTLEDGTEMPVPDDQLPVRLPEDVEM---DGVQSPIKADPEWCK-  478
            W  SRQRYWG PIP++  EDGT  +VP+ +LP+ LP   ++   +  +SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  479  TEYNGQPATLETDTFDTFMESSWYYARFCSPNYDKGMLDPAAANYWLPVDQYIGGIEHAI  538
            T  +G  +  ET+T      SSWYY R+  P+    + D    + WLPVD Y+GG EHA+
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  539  LHLLYARFFHKLLRDVGLVNSSEPFKRLLTQGMVLAETYYRNEANGGKTWYNPADVTVER  598
            LHLLYARF HK+L D+G+V + EPF++L+ QGM+L+ +Y   ++ G+     ++D    R
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY--RDSRGALV---ATDKVEKR  591

Query  599  DGKGQVVRAVLKSDGEPVEIGGVTKMSKSKNNGIDPQAIIDQHGADTVRLFMMFAAPPEQ  658
            DG    V +     GE +E  + +KMSKS +N ++P+ +++Q GADT+R++ MF +P + 
Sbjct  592  DGSFFHVET-----GEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  659  SLEWSDSGVEGAHRFLKRLWRMVNEHTAGGDAPAVDPANLNGAQKDLRRKTHETIAKVSD  718
            S+ WS+ G+EG+++FL R+ R++       + ++            L +  +ET+  V++
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLITTKEITEENSG-----------ALDKVYNETVKAVTE  694

Query  719  DISRRLTFNTAIAAVMELLNEVGRLSDDEPQSRAVRQEALDTAVLVLSPIVPHICHNLWQ  778
            ++  ++ FNTAIA +M ++N   +          +  +     V +++P+ PH+ ++LWQ
Sbjct  695  QVD-QMKFNTAIAQLMVFVNAANK-------EDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  779  ALGHSDAVVD-ASWPVADESAMVRSEIEVVLQVNGKVRAKENVPADIGKADLEKLALENE  837
            AL  S+  +   +WP  DES +V +++E+V+Q++GKV+AK  V+ D+++ +L+ +AL NE
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  838  NVMRFTDGKTVRKVIVVPGKLVNVVAN  864
            +V     GK + KVI VP KLVN+V +
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVIK  833

906) leuS in NC_021847


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  558 bits (2108),  Expect = 5e-160, Method: Compositional matrix adjust.
 Identities = 373/866 (44%), Positives = 559/866 (65%), Gaps = 49/866 (5%)

Query  5    YNPQDIEQKVQKHWDDNKTFVVSEDPNKEKFYCLSMFPYPSGR-LHMGHVRNYTIGDVVS  63
            Y+   IE K Q  W DN TF  + D++K KFY L MFPYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RFQRLQGKNVMQPIGWDAFGLPAENAAVKNNTAPAPWTYENIEYMKNQLKLLGFGYDWNR  123
            RF+R QG NV++P+GWDAFGLPAE+ A+     PA  T ENI   K Q++ LGF+YDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EFATCTPEYYRWEQEFFTKLYEKGLVYKKTSSVNWCPNDQTVLANEQV-EDGCCWRCDTP  182
            E  T  P+YY+W Q +FTKLYEKGL Y    +VNW  +  T +ANE+V  DG   R + P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VEQKEIPQWFIKITEYAQELLDDLDKLEGWPEMVKTMQRNWIGRSEGVELKFEVKG-QQD  241
            V +K + QW +KIT YA+ LL+DL+ ++ WPE +K MQRNWIG+S G ++ F VK+ ++D
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  242  LEVYTTRPDTLMGVTYVGIAAGHPL--ATLAAENNPELAAFI-EECKNTKVAEAELATME  298
            + V+TTRPDTL G TY  +A+ H+L  A  ++++   +A +  +   ++ +A ++LA  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  299  KKGMATGLTAIHPLNGREVPVYVANFVLMDYGTGAVMAVPAHDQRDFEFATKYGLDIIPV  358
            K G+ TG  AI+P+NG+E+PV +A++VL  YGTGA+MAVPAHD+RD EFA ++ LDIIPV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  359  IKPADGSELDISEAAYTEKGVLFDSGEFDGLEFQAAFDAIAAKLEAEGKGTKTVNFRLRD  418
            +  +     ++ EAA+TE G+ ++S+ +DGL+  +A+  +   LEAEG G   V +RLRD
Sbjct  362  LEGG-----NVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  419  WGVSRQRYWGAPIPMVTTEDGEVHPVPADQLPVILP--EDVVMDGVT-SPIKADKEWAKT  475
            W  SRQRYWG PIP++  EDG   +VP  +LP++LP   D+   G   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  476  TF-NGEPALRETDTFDTFMESSWYYARYCSPQADDIL-DPEKANYWLPVDQYIGGIEHAC  533
            T  +G  + RET+T      SSWYY RY  P+  + L D E  + WLPVD Y+GG EHA 
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  534  MHLLYSRFFHKLLRDAGYVTSDEPFKQLLCQGMVLADAFYFENEKGGKEWVAPTDVAVER  593
            +HLLY+RF HK+L D G V + EPF++L+ QGM+L+ +  + + +G+   + +TD    R
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS--YRDSRGA---LVATDKVEKR  591

Query  594  DGKGRIISAKDNEGRDVTHSGMIKMSKSKNNGIDPQEMVDKYGADTVRLFMMFASPADMT  653
            DG   ++     E  + + +   KMSKS +N ++P+++V++YGADT+R++ MF +P D +
Sbjct  592  DGS--FFHVETGEELEQAPA---KMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  654  LEWQESGVEGANRFLKRVWKLVKEHAEKGAAEAVDTAALSGEQKALRRDVHKTIAKVTDD  713
            + W E G+EG+ +FL RV +L+          +           AL +  + T+  VT++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLITTKEITEENSG-----------ALDKVYNETVKAVTEQ  695

Query  714  IARRQTFNTAIAAIMELMNKLAKAPQESAQDRAILDEALKAVVTMLYPITPHISYELWTA  773
            + + + FNTAIA +M ++N        + ++  ++ +  K+ V ++ P++PH++ ELW A
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  774  LGESD--IDNAAWPTFDEKALVEDEKTIVVQVNGKLRAKLTVAADATKEQVEELGLNDEN  831
            L  S+  I   +WP++DE  LVE++  IVVQ++GK++AKL VA D ++E+++E++L +E+
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  832  VTKFTDGLTIRKVIYVPGKLLNIVAN  857
            V     G  I KVI VP KL+NIV +
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVIK  833

907) leuS in NC_004603


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  558 bits (2108),  Expect = 5e-160, Method: Compositional matrix adjust.
 Identities = 373/866 (44%), Positives = 559/866 (65%), Gaps = 49/866 (5%)

Query  5    YNPQDIEQKVQKHWDDNKTFVVSEDPNKEKFYCLSMFPYPSGR-LHMGHVRNYTIGDVVS  63
            Y+   IE K Q  W DN TF  + D++K KFY L MFPYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RFQRLQGKNVMQPIGWDAFGLPAENAAVKNNTAPAPWTYENIEYMKNQLKLLGFGYDWNR  123
            RF+R QG NV++P+GWDAFGLPAE+ A+     PA  T ENI   K Q++ LGF+YDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EFATCTPEYYRWEQEFFTKLYEKGLVYKKTSSVNWCPNDQTVLANEQV-EDGCCWRCDTP  182
            E  T  P+YY+W Q +FTKLYEKGL Y    +VNW  +  T +ANE+V  DG   R + P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VEQKEIPQWFIKITEYAQELLDDLDKLEGWPEMVKTMQRNWIGRSEGVELKFEVKG-QQD  241
            V +K + QW +KIT YA+ LL+DL+ ++ WPE +K MQRNWIG+S G ++ F VK+ ++D
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  242  LEVYTTRPDTLMGVTYVGIAAGHPL--ATLAAENNPELAAFI-EECKNTKVAEAELATME  298
            + V+TTRPDTL G TY  +A+ H+L  A  ++++   +A +  +   ++ +A ++LA  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  299  KKGMATGLTAIHPLNGREVPVYVANFVLMDYGTGAVMAVPAHDQRDFEFATKYGLDIIPV  358
            K G+ TG  AI+P+NG+E+PV +A++VL  YGTGA+MAVPAHD+RD EFA ++ LDIIPV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  359  IKPADGSELDISEAAYTEKGVLFDSGEFDGLEFQAAFDAIAAKLEAEGKGTKTVNFRLRD  418
            +  +     ++ EAA+TE G+ ++S+ +DGL+  +A+  +   LEAEG G   V +RLRD
Sbjct  362  LEGG-----NVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  419  WGVSRQRYWGAPIPMVTTEDGEVHPVPADQLPVILP--EDVVMDGVT-SPIKADKEWAKT  475
            W  SRQRYWG PIP++  EDG   +VP  +LP++LP   D+   G   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  476  TF-NGEPALRETDTFDTFMESSWYYARYCSPQADDIL-DPEKANYWLPVDQYIGGIEHAC  533
            T  +G  + RET+T      SSWYY RY  P+  + L D E  + WLPVD Y+GG EHA 
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  534  MHLLYSRFFHKLLRDAGYVTSDEPFKQLLCQGMVLADAFYFENEKGGKEWVAPTDVAVER  593
            +HLLY+RF HK+L D G V + EPF++L+ QGM+L+ +  + + +G+   + +TD    R
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS--YRDSRGA---LVATDKVEKR  591

Query  594  DGKGRIISAKDNEGRDVTHSGMIKMSKSKNNGIDPQEMVDKYGADTVRLFMMFASPADMT  653
            DG   ++     E  + + +   KMSKS +N ++P+++V++YGADT+R++ MF +P D +
Sbjct  592  DGS--FFHVETGEELEQAPA---KMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  654  LEWQESGVEGANRFLKRVWKLVKEHAEKGAAEAVDTAALSGEQKALRRDVHKTIAKVTDD  713
            + W E G+EG+ +FL RV +L+          +           AL +  + T+  VT++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLITTKEITEENSG-----------ALDKVYNETVKAVTEQ  695

Query  714  IARRQTFNTAIAAIMELMNKLAKAPQESAQDRAILDEALKAVVTMLYPITPHISYELWTA  773
            + + + FNTAIA +M ++N        + ++  ++ +  K+ V ++ P++PH++ ELW A
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  774  LGESD--IDNAAWPTFDEKALVEDEKTIVVQVNGKLRAKLTVAADATKEQVEELGLNDEN  831
            L  S+  I   +WP++DE  LVE++  IVVQ++GK++AKL VA D ++E+++E++L +E+
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  832  VTKFTDGLTIRKVIYVPGKLLNIVAN  857
            V     G  I KVI VP KL+NIV +
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVIK  833

908) leuS in NC_011898


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  558 bits (2105),  Expect = 7e-160, Method: Compositional matrix adjust.
 Identities = 369/847 (44%), Positives = 545/847 (65%), Gaps = 57/847 (6%)

Query  5    ADIDRKWQKKWEETGIYRFNPEETDKKLYCLEMFSYPSGANLHVGHWYNYGLTDSWARMK  64
            + I+ KWQ  W +   ++   + +  K+Y L+MF+YPSGA LHVGH   Y  TD  +R K
Sbjct  7    TAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSRFK  66

Query  65   RMQGYNVFHPMGFDAFGLPAENYAIKTGIHPQDSTLKNIETMEGQLKEMGATFDWDYEIK  124
            R QG NV+HPMG DAFGLPAE+YA+ TG +P + T  NI     Q++ +G ++DWD E++
Sbjct  67   RAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDREVN  126

Query  125  TCMPDYYKWTQWLFLQLYKSGLAYRKNAPVNWCPKCNTVLANEQVV-DGCCERCDTEVTK  183
            T  P+YYKWTQW+F +LY  GLAY  + PVNW     T +ANE+V+ DG  ER +  V +
Sbjct  127  TTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVR  186

Query  184  RDLTQWFFKITAYAQELLDKLDTIDWPEKTKKIQTNWIGRSEGAEISFKVVDTDIEFQVF  243
            + + QW +KITAYA+ LL+ L+ +DWPE  K +Q NWIG+S GA+++FKV DTD +F VF
Sbjct  187  KPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVF  246

Query  244  TTRADTLYGVTYVVLAPENPIVENITRPEYAEAVEKYKNDTKKQTEIERLSTTKEKTGVF  303
            TTR+DTL+G TY VLAPE+++V+ IT ++ AEAV  YK ++  ++++ R   +KEKTGV 
Sbjct  247  TTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVW  306

Query  304  TGSYAIHPITGEKVPVWIADYVLASYGTGCVMAVPSHDERDFEFAKKYNLPIKRVIKSAD  363
            TGSYAI+P+ G  +PVWIADYVLASYGTG +MAVP+HDERD EFAK++NL I  V+ +  
Sbjct  307  TGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEG--  364

Query  364  GSNDELPYCEYGVLVNSSEFDGVPSTEARTAIIKKLEADGKGSLKINYRLRDWLVSRQRY  423
            G+ +E ++ E G+ +NS  +DG+  + A + ++  LEA+G G+ ++ YRLRDWL SRQRY
Sbjct  365  GNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRY  424

Query  424  WGAPIPVVYCEHCGEVAVPEENLPVTLPYNVEFKPD--GESPLKKSEEFMNTVCPKCGAT  481
            WG PIP++  E+    AVPE +LP+ LP   +++P   GESPL +  + ++ V    G  
Sbjct  425  WGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE-VTREDGVK  483

Query  482  AKRDPDTLDTFVCSSWYHLRYPDNRNNDKPFDTEWINKLLPVDKYVGGAEHAAMHLLYAR  541
            ++R+ +T+     SSWY LRY D +N +K  D E +++ LPVD YVGGAEHA +HLLYAR
Sbjct  484  GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYAR  543

Query  542  FITKALRDLGFLNFDEPFLSLVHQGTILAP------------------------------  571
            F  K L DLG +   EPF  L +QG IL+                               
Sbjct  544  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEE  603

Query  572  ---DGSKMSKSRGNTISPDDYVRKYGSDIFRMYLGFGFNYVDGGPWSDDGIKAISRFASR  628
                 +KMSKS  N ++PDD V +YG+D +R+Y  F      + +WS++G+ +  +F  R
Sbjct  604  LEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR  663

Query  629  IERLVESLAEQKSKASRTDIDKDDKELNFVRHTAIKGATQDTDRFQFNTAISRCMELVNA  688
            + RL+         +++   + +   L+ V + ++K+ T++ D+ +FNTAI++ M +VNA
Sbjct  664  VYRLI---------TTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNA  714

Query  689  LFKYDAEVKTKNIQLFEDTIKDLVKLVSPFAPHFAEEMWEQL-GCEYSLFNQKWPEFDEN  747
                      K+ +LF D  K++V+L++PFAPH++EE+W+ L +   S+    WP +DE+
Sbjct  715  --------ANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDES  766

Query  748  ALVKDTIELAVQVNGTVRGKieiaadadnsaaeaaaladekiKPFLDGKEikkvivvkGR  807
             LV + +E+ VQ++G V++K+ +A D      +  ALA+EK+++ + GK+I KVI V  +
Sbjct  767  KLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNK  826

Query  808  LVNIVAK  814
            LVNIV K
Sbjct  827  LVNIVIK  833

909) leuS in NC_008819


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  558 bits (2105),  Expect = 7e-160, Method: Compositional matrix adjust.
 Identities = 344/859 (41%), Positives = 563/859 (66%), Gaps = 39/859 (4%)

Query  13   YEPREVEAYWQKEWANDDLYRTNTEVNKENTFYALSMFPYPSG-SLHMGHVRNYVITDVL  71
            Y+   +E+ WQ  WA+++ ++T T+ +K + FYAL MFPYPSG +LH+GH   Y  TD+L
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPK-FYALDMFPYPSGAGLHVGHPEGYTATDIL  62

Query  72   ARYKRMKGLNVLHPMGWDSFGLPAENAAIERETSPSTWTDKNISQMKDQLDRLGLSIDWS  131
            +R+KR +G NVLHPMGWD+FGLPAE+ A++    P+  T  NI++ K Q++ LG+S DW 
Sbjct  63   SRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWD  122

Query  132  KEVTTCKEDYYKWTQYIFNQLHKNNLAYQKKATVNWDPIDQTVLANEQVDAEGKSWRSGA  191
            +EV T   +YYKWTQ IF +L  + LAY+    VNW     T +ANE+V ++G S R+G 
Sbjct  123  REVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGY  182

Query  192  KVEKKELNQWFLRITSFAEDLNKDLVTLNDWPDRVRVMQKNWIGKSIGAEITFDIKNSDQ  251
             V +K + QW L+IT++AE L  DL  + DWP+ ++ MQ+NWIGKS GA++TF +K++D+
Sbjct  183  PVVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDK  241

Query  252  KITAFTTRIDTVYGVSYLVLASNHPLIDQLISSNDIDKLNDFRQTQEKLSDLERNSDTRQ  311
             +T FTTR DT++G +Y VLA++H+L+D + +S++ + + D+++     SDL R   +++
Sbjct  242  DFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKE  301

Query  312  KLGMYLGVDAINPANNKEIPIWIGDYVIMEYGTGAVMGVPAHDSRDYQFAKSYDLPIQYV  371
            K G+  G  AINP N KE+P+WI+DYV+  YGTGA+M+VPAHD RD +FAK ++L I  V
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  372  IKPNIGEDESYLNAEFVDKGVMINSDKFNGIESDIAKTKILEFGSNSNWAKPKITYKLRD  431
            +     E+     A F + G+ INSD ++G++   A +K++E       ++ ++TY+LRD
Sbjct  362  LEGGNVEE-----AAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  432  WLISRQRYWGCPIPIIN--CKKCGQVRvpdddlpvvlpidiKLTGKGKSPLTTKTEWINT  489
            WL+SRQRYWG PIPII+        V  ++  L + +  DI+ +G G SPL+  T+W++ 
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  490  CCPKCGTDAKRETDTMDTFMCSSWYFLRYINPDNCEKPFLKSEIDKWLPVKQYVGGIEHA  549
                 G  ++RET+TM     SSWY+LRYI+P+N EK      + +WLPV  YVGG EHA
Sbjct  477  TRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  550  ILHLLYSRFLTKALKRCGLINIDEPFKKLLTQGMVQAVTFKNPNTNKYFSKDQIKDIDNP  609
            +LHLLY+RF  K L   G++   EPF+KL+ QGM+ + +++++      + D++   D +
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGA-LVATDKVEKRDGS  594

Query  610  -KDPLTGENIEIIYEKMSKSKYNGVDPSVVIDKYGADTARMFILFKAPPEKDLEWDDSDV  668
              +  TGE++E    KMSKS  N V+P  V+++YGADT R++ +F +P +  + W + ++
Sbjct  595  FFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGL  654

Query  669  EGQYRFIQRLWKFVINTFKLTNNNSRSNIEKEKSKDEEALRLINIAIKEITDDLDNLQFN  728
            EG  +F++R+ +++    K   +++ + ++K          + N ++K +T+++D+++FN
Sbjct  655  EGSRKFLDRVYRLITT--KEITEENSGALDK----------VYNETVKAVTEQVDQMKFN  702

Query  729  TAISELMKVVNGLS----LIVNYCSNETLNKVISILVKITSPFSPHIAEELWKTI-GNTQ  783
            TAI++LM  VN+ +    L+ +Y            +V++ +PF+PH++EELW+++ ++ +
Sbjct  703  TAIAQLMVFVNAANKEDKLFSDYAKG---------FVQLIAPFAPHLGEELWQALTASGE  753

Query  784  SIHLQSWPEFDAGAIEQDTFKLMIQINGKVRGSINASKNLSKENLEDLAIKTEAAIKWMD  843
            SI   +WP +D + + ++   +++QI+GKV++ +  +K+LS+E+L+++A+  E     + 
Sbjct  754  SISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIA  813

Query  844  GKEPKRIIVVPNKLVNIVI  862
            GK+  ++I VPNKLVNIVI
Sbjct  814  GKDIIKVIAVPNKLVNIVI  832

910) Lepto7376_3835 in NC_019683


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  557 bits (2102),  Expect = 1e-159, Method: Compositional matrix adjust.
 Identities = 377/851 (45%), Positives = 568/851 (67%), Gaps = 28/851 (3%)

Query  5    YSAADIESKWQQQWLELGLDQTPAKSDKPKFYALSMFPYPSGK-LHMGHVRNYVITDVIA  63
            Y  + IE+KWQ  W +    +T + + KPKFYAL MFPYPSG  LH+GH   Y  TD+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYKRMKGFRVLHPMGWDAFGLPAENAAIDRGIPPAKWTYQNIEQMRDQLKQLGLSIDWDR  123
            R+KR +G  VLHPMGWDAFGLPAE+ A+D G  PA  T +NI + + Q++ LG+S DWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVATCSPDYYKWTQWLFLQFYKSGLAYQKEAAVNWDPIDQTVLANEQVDAEGKSWRSGAI  183
            EV T  P+YYKWTQW+F ++Y  GLAY+ E +VNW     T +ANE+V ++G S R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  184  VEKKLLRQWFLKITDYAEELLQDLDQLGGWPDRVKTMQQNWIGKSSGALLEFLIVGSDEK  243
            V +K +RQW LKIT YAE LL+DL+++ +WP+ +K MQ+NWIGKS+GA + F + ++D  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  244  VAVFTTRPDTVYGVTYVVLAPEHPLvaqvttaaqkatvdaFIeevsneseeeRTADDkpk  303
             +VFTTRPDT++G TY VLAPEH+LV  +TT+ Q  +V  +  + S  S+  RT   K K
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEK  302

Query  304  kgvptggkvvnpFTGEEVPILIANYVLYEYGTGAVMGVPAHDTRDFKFAKENSLPIKTVI  363
             GV TG+  +NP  G E+P+ IA+YVL  YGTGA+M+VPAHD RD  FAK+ +L I  V+
Sbjct  303  TGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL  362

Query  364  IPEGGDASAELEEAYTEVGVMVNSGEFDGTVSTDGKQAIIKFAEEKGYGKERIQYRLRDW  423
              EGG+     E A+TE G+ +NS+ +DG   + +   ++   E  G G+E + YRLRDW
Sbjct  363  --EGGNVE---EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDW  417

Query  424  LISRQRYWGCPIPMIYCDDCGVVPVPEADLPVVLP--EDVEFSSRGGSPLAQMEDWKSVD  481
            L+SRQRYWG PIP+I  +D    +VPE++LP+VLP   D+  S+ G SPLA++ DW  V 
Sbjct  418  LFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT  477

Query  482  CPCCGKPARRETDTMDTFIDSSWYFLRYTDAKNEENPFKLDQVNDWMSVDQYVGGIEHAI  541
                 K +RRET+TM    +SSWY+LRY D+ N E+    + +++W++VD YVGG EHA+
Sbjct  478  REDGVK-GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  542  LHLLYSRFFTKVVRDNKLVSVDEPFKRLLTQGMVQALTYKNTKTNKYIPVDQIDPEDPK-  600
            LHLLY+RF  KV+ D  +V+  EPF++L+ QGM+ + +Y++++    ++ D+++  D   
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGA-LVATDKVEKRDGSF  595

Query  601  -DPETGDVLKGFYEKMSKSKYNGVDPQVVLSKYGADTARMFILFKAPPEKDLEWDDADVE  659
             + ETG+ L     KMSKS  N V+P+ V+ +YGADT R++ +F +P +  + W + ++E
Sbjct  596  FHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLE  655

Query  660  GQFRFLNRIWALVSGADLSATKEASGDYSKEEKDLRRAIHTAIKEIQEDLEGDYQFNTAI  719
            G  +FL+R+  L++  +++  + ++         L +  + ++K + E+++ + +FNTAI
Sbjct  656  GSRKFLDRVYRLITTKEITEENSGA---------LDKVYNETVKAVTEQVD-QMKFNTAI  705

Query  720  AELMKLSNALKDAKCTDSPVYAEGIKALLLLVAPFAPHLADELWQNL-GHAESIHTVDFP  778
            A+LM     + +A   +  ++++  K+++ L+APFAPHL++ELWQ L + +ESI  V  P
Sbjct  706  AQLM----VFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWP  761

Query  779  TLDKSALTVDEITLVIQIMGKTRGTIQVPAGASKAELEQFAKDSEAAQRYIEGKEIRKVI  838
            + D S L  +++ +V+QI GK ++ + V+ + S+ EL++ A  +E  Q  I GK+I KVI
Sbjct  762  SYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVI  821

Query  839  VVPNKLVNFVV  849
             VPNKLVN+V+
Sbjct  822  AVPNKLVNIVI  832

911) leuS in NC_008570


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  557 bits (2103),  Expect = 1e-159, Method: Compositional matrix adjust.
 Identities = 360/866 (42%), Positives = 562/866 (65%), Gaps = 47/866 (5%)

Query  56   YVPQSIEPAVQKHWDAKKTFKAVEKVDKEKFYCLSMFPYPSGR-LHMGHVRNYTIGDVIS  114
            Y   +IEP  Q  W  + TFK+     K KFY L MFPYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  115  RYQRLNGKNVLQPIGWDAFGLPAENAAIKNNTAPAPWTYENIEYMKNQLKMLGLGYDWDR  174
            R++R +G NVL+P+GWDAFGLPAE+ A+     PA  T ENI   K Q++ LG++YDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  175  ELATCKPDYYRWEQWFFTKLYEKGLVYKKTSSVNWCPNDMTVLANEQVV-DNCCWRCDTP  233
            E+ T  P+YY+W QW+FTKLYEKGL Y    +VNW  +  T +ANE+V+ D    R + P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  234  VEQKEIPQWFIKITDYAEELLNDIDNLEGWPEMVKTMQRNWIGRSEGVNISFAIEGQTEH  293
            V +K + QW +KIT YAE LL+D+++++ WPE +K MQRNWIG+S G N++F + +   +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  294  LEVYTTRPDTFMGVTYVGIAAGHPL--ALQAAESNPELAAFI-EECKNTKVAEAELATME  350
            + V+TTRPDT+ G TY  +A+ H+L  A+ +++    +A +  +   ++ +A ++LA  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  351  KKGMATGLYAIHPLDGRKVPVWVANFVLMNYGTGAVMAVPGHDLRDHEFATKYGLEIKPV  410
            K G+ TG YAI+P++G+ +PVW+A++VL +YGTGA+MAVP+HD RD EFA ++ L+I PV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  411  IKPVDGELPNVIDAAYTDKGVLFNSGEFDGLEFQPAFDAIASKLESLGCGKRTVNFRLRD  470
            +        NV +AA+T+ G+ +NS+ +DGL+  +A+  +   LE+ G G+  V +RLRD
Sbjct  362  LEG-----GNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  471  WGVSRQRYWGAPIPMLTLADGTVVPTPEDQLPVLLP--EDVVMDGI-QSPIKADAEWAKT  527
            W  SRQRYWG PIP++   DGT  + PE +LP++LP   D+   G  +SP+   ++W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  528  TY-NGQEAFRETDTFDTFMESSWYYARYCSPDYDKGMLDPAAANHWLPVDQYIGGIEHAC  586
            T  +G  + RET+T      SSWYY RY  P+    + D    ++WLPVD Y+GG EHA 
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  587  MHLLYARFFHKLLRDAGLVNSDEPFKRLLCQGMVLADAFYYKDEKGGNVWVSPTDVKVER  646
            +HLLYARF HK+L D G+V + EPF++L+ QGM+L+ +  Y+D +G+ V    +  KVE+
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS--YRDSRGALV----ATDKVEK  590

Query  647  DEKGRITKAVDNEGREVIHSGMTKMSKSKNNGIDPQLMVERYGADTVRLFMMFASPAEMT  706
                R     + E  E ++ + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P + +
Sbjct  591  ----RDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  707  LEWSDSGVEGAQRFLRRLWR-ITFEHVSAGVAPALNVAALSVDQKAVRRELHKTIAKVSD  765
            + WS+ G+EG+++FL R+ R IT  +++   + AL+            +  + T+  V++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALD------------KVYNETVKAVTE  694

Query  766  DVGRRQTFNTAIAAIMELMNNLAKLGSDEQDRALMQEALEAVVVMLYPITPHIGFELWKM  825
            +V++ + FNTAIA +M ++N      + +++  L  +   + V ++ P++PH+G ELW+ 
Sbjct  695  QVDQMK-FNTAIAQLMVFVN------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  826  L-GKGDDVDHATWPVADEAAMVETEKLVVVQINGKMRGKLTVPAEISQADVEKLAMADAS  884
            L + G+ +    WP  DE+ +VE +  +VVQI+GK+++KL V+ ++S+ +++ +A+A+  
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  885  VQKFTDGLTVRKVIYVPGKLLNIVAN  910
            VQ    G  + KVI VP KL+NIV +
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVIK  833

912) leuS in NC_018678


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  557 bits (2104),  Expect = 1e-159, Method: Compositional matrix adjust.
 Identities = 362/874 (42%), Positives = 560/874 (65%), Gaps = 56/874 (6%)

Query  6    YNPKDIEQRVQQYWEENQSFKANDDVEKEKFYCLSMFPYPSGR-LHMGHVRNYTIGDVIS  64
            Y+   IE + Q +W +N++FK+  D  K KFY L MFPYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  65   RFQRMQGKNVLQPMGWDAFGLPAENAAINNNTAPAKWTYSNIDYMKNQLRSLGFGYDWDR  124
            RF+R QG NVL+PMGWDAFGLPAE+ A++    PA  T  NI   K Q+ +LGF+YDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  125  EVTTCKSDYYRWEQWFFTRLYEKGLVYKKNSTVNWDPVDQTVLANEQVI-DGRGWRSGAL  183
            EV T  ++YY+W QW+FT+LYEKGL Y  +  VNW     T +ANE+V+ DG + R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  184  VEQKEIPQWFIKITDYAeellqdleqleeWPDQVRAMQANWIGRSEGVEITFDLASAVND  243
            V +K + QW +KIT YA E L +  +  +WP+ ++ MQ NWIG+S G ++TF +  + + 
Sbjct  184  VVRKPMRQWMLKITAYA-ERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDK-  241

Query  244  IADLTVYTTRPDTFYGVTYVAVAAQHPLAEFAAKSNPDLAAFIDECKNTKVAEAELA---  300
              D+TV+TTRPDT++G TY  +A++H+L +  A + +D A  + + K      ++LA   
Sbjct  242  --DFTVFTTRPDTLFGATYAVLAPEHALVD--AITTSDQAEAVADYKRQASLKSDLARTD  297

Query  301  -TMEKKGFATGFEVVHPLTGEKLPIWVANFVLMDYGSGAVMAVPGHDQRDWEFATKYNLP  359
             + EK G  TG   ++P+ G  +P+W+A++VL  YG+GA+MAVP+HD+RDWEFA ++NL 
Sbjct  298  LAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLD  357

Query  360  IQQVIAPNAGDEDKCDLTVSAFTEKGSLINSGKFDGLEFDAAFNGIADELESKGCGKRKV  419
            I  V+     +E       +AFTE G  INS+ +DGL+  +A+  + + LE+ G G+ +V
Sbjct  358  IIPVLEGGNVEE-------AAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENV  410

Query  420  NYRLRDWGVSRQRYWGAPIPMLNLENGESVPVPADQLPVVLP--EDVEMNGVT-SPIKAD  476
             YRLRDW  SRQRYWG PIP+++ E+G S +VP  +LP+VLP   D+  +G   SP+   
Sbjct  411  TYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANV  470

Query  477  PEWAKTTY-NGEAALRETDTFDTFMESSWYYARYACATNNDAMLDPTSANYWLPVDQYIG  535
             +W   T  +G  + RET+T      SSWYY RY  + N + + D    + WLPVD Y+G
Sbjct  471  TDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVG  530

Query  536  GIEHAILHLLYSRFFHKLLRDEGLVNSDEPFKRLLCQGMVLADSYYREDASGKKTWFSPT  595
            G EHA+LHLLY+RF HK+L D G+V + EPF++L+ QGM+L+ S YR+  ++        
Sbjct  531  GAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS-YRDSRGAL-------  582

Query  596  EVSTEKDDKGRIVKAWLTADGEEVIHGGMTKMSKSKNNGIDPQEVIDQYGADTVRLFTMF  655
             V+T+K +K     + +  +  E ++ + +KMSKS +N ++P++V++QYGADT+R++ MF
Sbjct  583  -VATDKVEKRD--GSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMF  639

Query  656  AAPPEQTLEWVDSGVEGANRFLRRIWKLVTEHVEKGAPEAIDVKALSKDQQ-ALRREVHK  714
             +P + ++ W + G+EG+ +FL R+ +L+T             K ++ ++  AL +  + 
Sbjct  640  MGPLDASIAWSEEGLEGSRKFLDRVYRLIT------------TKEITEENSGALDKVYNE  687

Query  715  TIEKVSDDLGRRQTFNTAVAAVMELLNHLQKAPQENAQDIAIMREACESILLLLNPITPH  774
            T+  V++++++ + FNTA+A +M ++N  +K  +       +  +   +++ L+ P++PH
Sbjct  688  TVKAVTEQVDQMK-FNTAIAQLMVFVNAANKEDK-------LFSDYAKGFVQLIAPFAPH  739

Query  775  IAHELWKVL-GHSEDIDLAPWPQADKSALVEDEKLIIVQVNGKVRAKMTIAADASKESIE  833
            +++ELW+ L + +E I   PWP  D S LVE++  I+VQ++GKV+AK+ +A D S+E ++
Sbjct  740  LGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQ  799

Query  834  ASAKEQPNVQQFIEGKTIRKVIVVPGKLVNIVAN  867
              A  + +VQ  I GK I KVI VP KLVNIV +
Sbjct  800  EVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

913) leuS in NC_012225


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  557 bits (2103),  Expect = 1e-159, Method: Compositional matrix adjust.
 Identities = 359/866 (42%), Positives = 558/866 (65%), Gaps = 51/866 (5%)

Query  3    YNFTTIEKKWQKFWKDNQSFKTVSKPTDKKYYVLEMFPYPSGK-MHMGHVSNYTIADSIA  61
            Y+ T+IE KWQ FW DN++FKT + ++  K+Y L+MFPYPSG  +H+GH   YT +D ++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  62   RYYKLLGYDILHPMGWDAFGMPAENAAIEHKTHPAEWTLKNIANMKDQLNLLGYSYDWDR  121
            R+ +  G ++LHPMGWDAFG+PAE+ A++   +PAE T  NIAN K Q+N LG+SYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  122  EVTTCLPDYYKWGQWFILKMYEKGLLYRKGGDVNWCDHCNTVLANEQVTPEGTCWRCDGE  181
            EV T  P+YYKW QW++ K+YEKGL Y     VNW ++  T +ANE+V P+GT  R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VTKKKLEQWYIKVTDYAEQLDADLKLLEGYWPDNVIAMQKNWIGRSVGAYINFNL-DDGK  240
            V +K + QW +K+T YAE+L  DL  ++  WP+++  MQ+NWIG+S GA + F++ D +K
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD--WPESIKDMQRNWIGKSTGANVTFKVKDTDK  241

Query  241  AFPIFTTRPDTIYGVTYMAIAWNYDGLLD-MCTTEQKSAVEEFIKKSA-KID-QKTDYEK  297
             F +FTTRPDT++G TY  +A   ++L+D + T++Q  AV ++ ++++ K D  +TD  K
Sbjct  242  DFTVFTTRPDTLFGATYAVLA-PEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  298  E--GVFTGRYVVNPFNGEKAPLYAANFVLAEYGSGAVMAVPAHDQRDFEFAKKYNIPVKV  355
            E  GV TG Y +NP NG   P+  A++VLA YG+GA+MAVPAHD+RD EFAK++N+ +  
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  356  VIQNADNSLKAENMTEAYTEDGTVVNSDILNGLSSRDAIKRAIEYATEKGFGKEKVQYKL  415
            V++ ++          A+TEDG  +NSD+L+GL    AI + +E     G G+E+V Y+L
Sbjct  361  VLEGGNVE------EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRL  414

Query  416  RDWLISRQRYWGNPLPFVHCEKCGVVPVPESELPITLPMDIEF---TVGDNPLKKSESFV  472
            RDWL+SRQRYWG+P+P++H E     +VPESELP+ LP+  ++     G++PL +    +
Sbjct  415  RDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWL  474

Query  473  NTTCPKCGGKARRETDTMDTFTCSSWYYARYTDAHNNQMPFDPSAANAWLGVDQYIGGIE  532
            + T    G K+RRET+TM   + SSWYY RY D+HN +   D    + WL VD Y+GG E
Sbjct  475  EVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAE  533

Query  533  HACMHLLYSRFWYKFMRDIGLVKGDEPFNRLLTQGMVLANSY-ESRELKKFYTQEQMNNK  591
            HA +HLLY+RFW K + D+G+V   EPF++L+ QGM+L+ SY +SR    + + ++++++
Sbjct  534  HAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRG--ALVATDKVEKR  591

Query  592  E---YEKDGIKKEDIIVKMEKMSKSKANGIDPAEIIELFGADAVRIFVMFVAPPEKDKEW  648
            +   ++ +    E++     KMSKS  N ++P +++E +GAD++R++ MF++P +    W
Sbjct  592  DGSFFHVE--TGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAW  649

Query  649  SDEGVKGSSRFLNRIWNLFLKYKDEEAFKNGKSFDYNNLSKEGQKLFRKYNktikkvtid  708
            S+EG+ GS +FL+R+  L+                 ++++ E    + K  +   K   +
Sbjct  650  SEEGLEGSRKFLDRVYRLITT---------------KEITEENSGALDKVYNETVKAVTE  694

Query  709  ikdRFHFNTAIAALMELLNDMSVIKLANNDDYAMFKEVIRGYLILLNPIAPHMTEELYQI  768
              D+  FNTAIA LM ++N       A N +  +F +  +G++ L+ P+APH+ EEL Q 
Sbjct  695  QVDQMKFNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  769  LNFGKMILE-ERWVEHDEQYCKDDTFELVFQVNGKIRDRVEADVNISEDDAKAQALASEK  827
            L  +   +    W   DE    ++  E+V Q++GK++ ++    ++S ++ +  ALA+EK
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  828  VKAFTDGKNIVKVVYVKGKLVNIVVK  853
            V+A   GK+I+KV+ V  KLVNIV+K
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVIK  833

914) leuS in NC_006300


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  557 bits (2103),  Expect = 1e-159, Method: Compositional matrix adjust.
 Identities = 359/866 (42%), Positives = 570/866 (66%), Gaps = 46/866 (5%)

Query  5    YRPDLLEQEVQKYWQNNQTFKAVKDSSKEKYYCLSMFPYPSGR-LHMGHVRNYTIADVVS  63
            Y    +E   Q +W +N+TFK+  D+SK K+Y L MFPYPSG  LH+GH   YT +D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMNGKNVLQPVGWDAFGLPAEGAAVKNKTAPAKWTYENIDYMKNQLKMLGFSYDWDR  123
            R++R +G NVL+P+GWDAFGLPAE  A+     PA  T ENI   K Q++ LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EIATCKPEYYKWEQWFFTELYKKGLVYKKTSVVNWCPNDETVLANEQV-HEGCCWRCDTP  182
            E+ T  P+YYKW QW+FT LY KGL Y     VNW  +  T +ANE+V  +G   R + P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VEQKEIPQWFIKITDYAEQLLSGLDTLPEWPDMVKTMQRNWIGRSEGVEITFKIENSDET  242
            V +K + QW +KIT YAE+LL +L+ + +WP+ +K MQRNWIG+S G ++TFK+ ++D  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  VAVYTTRPDTFYGVSYMAVAAGHPLAE--KAAQNNAELARFIQECK-NTKVAEAELATME  299
             +V+TTRPDT++G +Y  +A+ H+L +   ++++   +A + ++   ++ +A ++LA  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGMATGINAIHPITGKPVPVWVANFVLMHYGTGAVMAVPAHDQRDFEFATKYGLPIKQV  359
            K G+ TG  AI+P+ GK +PVW+A++VL  YGTGA+MAVPAHD+RD EFA ++ L   ++
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNL---DI  358

Query  360  IAPMNGEEIDLTKAAFTEHGKLVNSAEFDGLDFEAAFNGIADKLEKMGVGKRQVNYRLRD  419
            I+ ++G +++   AAFTE+G  +NS  +DGLD  +A+  + + LE  GVG+ +V YRLRD
Sbjct  359  IPVLEGGNVE--EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMLTLENGDVVPAPLQDLPIVLP--EDVVMDGV-KSPIKADPDWAK-  475
            W  SRQRYWG PIP++  E+G   + P  +LP+VLP   D+   G   SP+    DW   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  476  TSYNGQPALKETDTFDTFMESSWYYARYTSPQYHEGMLDSDEANYWLPVDQYIGGIEHAT  535
            T  +G  + +ET+T      SSWYY RY  P+  E + D +  + WLPVD Y+GG EHA 
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLLYFRFFHKLLRDAGLVSTDEPTKKLLCQGMVLADAFYYTSPTNERIWVSPTKVMLER  595
            +HLLY RF HK+L D G+V+T EP +KL+ QGM+L+ ++     +   + V+  KV  E+
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY---RDSRGAL-VATDKV--EK  590

Query  596  DEKGRILKATDDEGHELVHAGMTKMSKSKNNGIDPQEMVEKYGADTVRLFMMFASPAEMT  655
             + G ++    + G+EL +A  +KMSKS +N ++P+++VE+YGADT+R++ MF +P + +
Sbjct  591  RD-GSFFHV--ETGEELEQAP-AKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  656  LEWQESGVEGAKRFLGRLWNLVFEYNKNPVKTAPNPTALSSAQKALRRDVHKTIAKVSDD  715
            + W E G+EG+++FL+R+      Y     K   +  +      AL +  + T+  V+++
Sbjct  647  IAWSEEGLEGSRKFLDRV------YRLITTKEITEENS-----GALDKVYNETVKAVTEQ  695

Query  716  IGRRQTFNTAIAAIMELMNKLTRAPLTDEQDRAVMGEALSAVVRMLYPITPHICFQLWKD  775
            +++ + FNTAIA +M ++N       + +++  + ++   + V+++ P++PH+  +LW+ 
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  776  L-GNEDIIDFAPWVQADEAAMIDDEKLVVVQVNGKVRGKITVPADMAEEEIKRVALAEEN  834
            L ++ + I + PW   DE+ +++++  +VVQ++GKV++K+ V+ D++ EE++ VALA+E+
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  835  VQKFLDGLNIVKVIYVPGKLLSFVAK  860
            VQ  + G +I+KVI VP KL+++V K
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVIK  833

915) leuS in NC_017068


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  557 bits (2102),  Expect = 1e-159, Method: Compositional matrix adjust.
 Identities = 361/860 (42%), Positives = 535/860 (63%), Gaps = 69/860 (8%)

Query  4    YSPQEIEKKWQDKWEADSAFKTEMDETRPKYYALEMFPYPSG-NLHMGHVRNYSIGDVMA  62
            Y    IE KWQ  W  + +FKT  D ++PK+YAL+MFPYPSG  LH+GH   Y+  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKTMEGFNVLHPMGFDSFGMPAENAAIKHNVKPSDWTFSNIENMKRQQRSMGLSYDWDR  122
            R+K  +G NVLHPMG D+FG+PAE+ A+     P++ T  NI N KRQ  ++G+SYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EAITCTPEYYKWTQWLFELFYKKGLAYKKKASVNWCDTCGTVLANEQVI-DGKCWRCDSE  181
            E  T  P+YYKWTQW+F  +Y KGLAY    +VNW +  GT +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VQKKDLSQWFLKITDYAdvllkdldklkGWPERVKTMQDNWIGRSEGLEFEMPVEGMEEK  241
            V +K + QW LKIT YA   L +     +WPE +K MQ NWIG+S G +    V + +  
Sbjct  184  VVRKPMRQWMLKITAYA-ERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  242  LSVYTTRPDTAYGITFVALAAENPLVEKICENNPKAAEIKAFCDKVRNQSEMERTSSESE  301
            ++V+TTRPDT +G T+  LA+E++LV+ I  ++ +A  +  +  +   +S++ RT    E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSD-QAEAVADYKRQASLKSDLARTDLAKE  301

Query  302  KEGIFTGVYAINPFNGNKAQLWVTNYVLADYGTGAVMGVPSGDQRDWMFAKKYDLPIILT  361
            K G+ TG YAINP NG+   +W+++YVLA YGTGA+M+VP+ D+RDW FAK+++L II  
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  362  LQPKGKELKLEEMDAAYTDKDGVLVNSGKFTGMEIHKAMSGIIDEAEAQGFGKRKVNYRL  421
            L+    E      +AA+T+ DG+ +NS+ + G++   A++ +++  EA+G G+ +V YRL
Sbjct  362  LEGGNVE------EAAFTE-DGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRL  414

Query  422  RDWLISRQRYWGAPIPVIHCPHCGEVLVPEEDLPVRLP--EDVSFDSGALSPLATSEAFV  479
            RDWL+SRQRYWG PIP+IH  +     VPE +LP+ LP   D+   + + SPLA     +
Sbjct  415  RDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWL  474

Query  480  NCKCPKCGADAKRETDTMDTFICSSWYYLRYTDPKNDKAPFAKDKVNYWAPVDQYIGGIE  539
            +      G  ++RET+TM     SSWYYLRY DP N       + ++ W PVD Y+GG E
Sbjct  475  EVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAE  533

Query  540  HAILHLLYSRFFTKVLHDAGLVDFDEPFSNLLTQGMVL-------------------KDG  580
            HA+LHLLY+RF  KVL D G+V   EPF +L+ QGM+L                   +DG
Sbjct  534  HAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDG  593

Query  581  S---------------KMSKSKGNVVSPEEIIAKYGADTARLFILFAAPVDRDLEWSDQG  625
            S               KMSKS  NVV+P++++ +YGADT R++ +F +P+D  + WS++G
Sbjct  594  SFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEG  653

Query  626  VEGAFRFLGRVWRILDHFEDMVKAGKDEYDVAALTKEEKELRRVLHVTIKKVTEDIRDRF  685
            +EG+ +FL+RV R++       K   +E        +   L +V + T+K VTE++ D+ 
Sbjct  654  LEGSRKFLDRVYRLIT-----TKEITEE--------NSGALDKVYNETVKAVTEQV-DQM  699

Query  686  MFNTAISSIMELVNAAYAFQDKELNAGLAREFAAALIKMLAPFAPHITEELWSNLFGEG-  744
             FNTAI+ +M +VNAA    +KE    L  ++A ++++++APFAPH+ EELW  L + G 
Sbjct  700  KFNTAIAQLMVFVNAA----NKE--DKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGE  753

Query  745  SVHQQQWPKYEEEATKLAEIEIVLQINGKVRDRITLPADIDRAAMEEAVKELPRAKELTE  804
            S+    WP Y+E      ++EIV+QI+GKV+ ++ ++ D+ R  ++E      + +    
Sbjct  754  SISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIA  813

Query  805  GKTIVKVICVPKKLVNIVVK  824
            GK I+KVI VP+KLVNIV+K
Sbjct  814  GKDIIKVIAVPNKLVNIVIK  833

916) leuS in NC_008309


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  557 bits (2102),  Expect = 1e-159, Method: Compositional matrix adjust.
 Identities = 353/868 (41%), Positives = 569/868 (66%), Gaps = 50/868 (5%)

Query  5    YRPDLIEADVQKYWAEKKTFKAVKDPSKEKYYCLSMFPYPSGR-LHMGHVRNYTIGDVIS  63
            Y    IE+  Q +WA++ TFK+  D+SK K+Y L MFPYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMNGKNVLQPMGWDAFGLPAEGAAIKNKTAPAKWTYENIEYMKNQLKVLGFGFDWDR  123
            R++R +G NVL+PMGWDAFGLPAE  A+     PA  T ENI   K Q++ LGF++DWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EITTCKPEYYKWEQWFFTELYKKGLVYKKTSTVNWCPNDETVLANEQV-HEGCCWRCDTP  182
            E+ T  P+YYKW QW+FT LY KGL Y     VNW  +  T +ANE+V  +G   R + P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VEQKEIPQWFIKITDYAEQLLSDLDQLPEWPDMVKTMQRNWIGRSEGVEITFNVAHSDQT  242
            V +K + QW +KIT YAE+LL DL+++ +WP+ +K MQRNWIG+S G ++TF+V ++D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFYGVSYLAVAAAHPLAESAAKNNP--ELAAFIHEAK-NTKVAEAELATME  299
            +TV+TTRPDT++G +Y  +A+ H+L ++ + ++    +A + ++A  ++ +A ++LA  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGMATGLYAVHPMTGKQLPIWVANFVLMHYGTGAVMAVPAHDQRDYEFAQKYQLPLFPV  359
            K G+ TG YA++P+ GK++P+W+A++VL  YGTGA+MAVPAHD+RD EFA++++L ++PV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  360  IKPADNSAWDFSKQAYTEHGITINSAEFDGLDFEATFNGIADKLEKIGVGKRQVNYRLRD  419
            +  ++         A+TE+G+ INS  +DGLD  +++  + + LE  GVG+ +V YRLRD
Sbjct  362  LEGGNVEE-----AAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMLTLENGDVVVAPLQDLPIVLP--EDVVMDGV-KSPIKADPEWAKT  476
            W  SRQRYWG PIP++  E+G     P  +LP+VLP   D+   G   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  TY-NGQAALKETDTFDTFMESSWYYARYTSPQYQQAMLDADEANYWLPVDQYIGGIEHAT  535
            T  +G  + +ET+T      SSWYY RY  P+  + + D +  + WLPVD Y+GG EHA 
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLLYFRFFHKLLRDAGFVTSDEPSKKLLCQGMVLADAFYYTSPTNERIWVSPTKVTLER  595
            +HLLY RF HK+L D G V + EP +KL+ QGM+L+ ++      + R     + V+ ++
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSR----GALVATDK  587

Query  596  DEK--GRIIKAVDDEGHELVHSGMTKMSKSKNNGIDPQEMVEKYGADTVRLFMMFASPAE  653
             EK  G ++    + G+EL ++  +KMSKS +N ++P+++VE+YGADT+R++ MF +P +
Sbjct  588  VEKRDGSFFHV--ETGEELEQAP-AKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLD  644

Query  654  MTLEWQESGVEGANRFLRRLWNLVFEYNQNPAQTALDPTALSVEQKALRRDVHKTIAKVS  713
             ++ W E G+EG+ +FL R+  L+        + + + ++      AL +  + T+  V+
Sbjct  645  ASIAWSEEGLEGSRKFLDRVYRLI-----TTKEITEENSG------ALDKVYNETVKAVT  693

Query  714  DDIGRRQTFNTAIAAIMELMNKLTKASLSNEQDRAVMAEALNAVVRMLYPITPHICFQLW  773
            +++++ + FNTAIA +M ++N       + +++  + ++  ++ V+++ P++PH+  +LW
Sbjct  694  EQVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELW  745

Query  774  QDL-GNESTIDFAPWVIADAEAMVEDEKLVVIQVNGKVRAKVTVPADMSEDEIKQVALAE  832
            Q L ++  +I + PW   D   +VE++  +V+Q++GKV+AK+ V+ D+S +E+++VALA+
Sbjct  746  QALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALAN  805

Query  833  ENVQKFLNGLTVVKTIYVQGKLFSFVAK  860
            E+VQ  + G  ++K I V  KL ++V K
Sbjct  806  EKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

917) Halsa_1703 in NC_014654


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  557 bits (2101),  Expect = 2e-159, Method: Compositional matrix adjust.
 Identities = 384/867 (45%), Positives = 572/867 (66%), Gaps = 75/867 (8%)

Query  4    YYPFHKVEEKWLSRWEKSNLDKTGTDPDKENYYVLEMFPYPSG-NLHMGHVRVYSIGDVV  62
            +Y    +E KW + W  ++  KTGTD+ K ++Y L+MFPYPSG  LH+GH   Y+  D++
Sbjct  3    FYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDIL  62

Query  63   ARYKRMEGYNVLHPMGWDAFGLPAENAAIKHGNIHPKEWTWQNIAHMKEQMKAMGLSYDW  122
            +R+KR +G NVLHPMGWDAFGLPAE+ A+  GN +P E T +NIA+ K Q++A+G+SYDW
Sbjct  63   SRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGN-DPAEFTAENIANFKRQINALGFSYDW  121

Query  123  DREVTTASKDYYKWTQWFFAKMFERDLAYRKESTVNWCPSCETVLANEQVVNEG-CERCG  181
            DREV T+  +YYKWTQW+F+K++E++LAY  E  VNW     T +ANE+V+ +G  ER G
Sbjct  122  DREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGG  181

Query  182  TEVEPRELEQWFLKITDYADRLLDDFKELDNWPEKVKTMQKNWIGRSEGTRINFPLKDLN  241
              V  + + QW LKIT YA+RLL+D+ E+D WPE +K MQ+NWIG+S G+ + F +KD +
Sbjct  182  YPVVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  242  EHLEVFTTRPDTLYGATYMVLAPEHPLVSDLTEGTDKEQEIKDFIAKVKKQKEEERTSAE  301
             ++ VFTTRPDTL+GATY VLAPEH+LV  +T  +D+ + + D+  +   + +  RT   
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAIT-TSDQAEAVADYKRQASLKSDLARTDLA  299

Query  302  TEKLGIFTGAYAINPVNEKEIPIYIANYVLMSYGTGAIMAVPAHDQRDFDFAKKYDIPIK  361
             EK G+ TG+YAINPVN KE+P+ IA+YVL SYGTGAIMAVPAHD+RD +FAK++++ I 
Sbjct  300  KEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDII  359

Query  362  AVIQPedeeekfkgsemeeAYADDGYLINSDKYNGLSVDEAFNKMAEDFSKAGFAKLETN  421
            +V++  + EE         A+++DG  INSD  +GL    A+ KM E +   G ++ +  
Sbjct  360  PVLEGGNVEEA--------AFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVT  411

Query  422  YRLRDWLISRQRYWGAPIPIVYCDDCGAVAVPEEDLPVELPHDVEFSPSG--ESPLKKVD  479
            YRLRDWL+SRQRYWG PIPI+  +D  + AVPE +LP+ LP   ++ PSG  ESPL +V 
Sbjct  412  YRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVT  471

Query  480  EFVNTTCPQCGGAAKRETDTMDTFVDSSWYFLRYTDANNEHKAFSKAKADKWFPVDQYIG  539
            + ++ T  + G  ++RET+TM    +SSWY+LRY D++N +K        +W+PVD Y+G
Sbjct  472  DWLEVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVG  530

Query  540  GIEHAILHLLYSRFFTKVVHDMGMAEAVEPFTNWLAQGMVL-------------------  580
            G EHA+LHLLY+RF  KV+ D+G+  + EPF + + QGM+L                   
Sbjct  531  GAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEK  590

Query  581  KDG---------------AKMSKSKGNVVDPKDILEEYGADTARLFILFASPPEKDLEWS  625
            +DG               AKMSKS  NVV+P D++E+YGADT R++ +F +P +  + WS
Sbjct  591  RDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWS  650

Query  626  NKGVEGANRFLNRVWRYITENIEIIRSGEGEVIADELDKEAKKLYRIMHSSIKKVSEDIG  685
            + G+EG+ +FL+RV R IT +           I++E      K+Y   + ++K V+E++ 
Sbjct  651  EEGLEGSRKFLDRVYRLITTK----------EITEENSGALDKVY---NETVKAVTEQV-  696

Query  686  ERLNFNTAISAIMELTNEVYSYLNDRDNAEINSSLLRAAAENTllllapfapflSEELWE  745
            ++++FNTAI+ +M     V+    ++++      L+   A   + L+APFAP L+EELW+
Sbjct  697  DQMKFNTAIAQLM-----VFVNAANKED-----KLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  746  KI-GYEESIHKGSWPEYNEAALEKDEITIVIQINGKVREKINVDADIsesevkekvmkee  804
             + +  ESI   +WP Y+E+ L  +++ IV+QI+GKV+ K+ V  D+S  E++E  + +E
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  805  kvksYLEGNELVKTIYVPSKLVNLVIK  831
            KV++ + G++++K I VP+KLVN+VIK
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVIK  833

918) VPBB_0698 in NC_019955


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  557 bits (2101),  Expect = 2e-159, Method: Compositional matrix adjust.
 Identities = 372/866 (43%), Positives = 559/866 (65%), Gaps = 49/866 (5%)

Query  5    YNPQDIEQKVQKHWDDNKTFVVSEDPNKEKFYCLSMFPYPSGR-LHMGHVRNYTIGDVVS  63
            Y+   IE K Q  W DN TF  + D++K KFY L MFPYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RFQRLQGKNVMQPIGWDAFGLPAENAAVKNNTAPAPWTYENIEYMKNQLKLLGFGYDWNR  123
            RF+R QG NV++P+GWDAFGLPAE+ A+     PA  T ENI   K Q++ LGF+YDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EFATCTPEYYRWEQEFFTKLYEKGLVYKKTSSVNWCPNDQTVLANEQV-EDGCCWRCDTP  182
            E  T  P+YY+W Q +FTKLYEKGL Y    +VNW  +  T +ANE+V  DG   R + P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VEQKEIPQWFIKITEYAQELLDDLDKLEGWPEMVKTMQRNWIGRSEGVELKFEVKG-QQD  241
            V +K + QW +KIT YA+ LL+DL+ ++ WPE +K MQRNWIG+S G ++ F VK+ ++D
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  242  LEVYTTRPDTLMGVTYVGIAAGHPL--ATLAAENNPELAAFI-EECKNTKVAEAELATME  298
            + V+TTRPDTL G TY  +A+ H+L  A  ++++   +A +  +   ++ +A ++LA  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  299  KKGMTTGLTAIHPLNGREVPVYVANFVLMDYGTGAVMAVPAHDQRDFEFATKYGLDIIPV  358
            K G+ TG  AI+P+NG+E+PV +A++VL  YGTGA+MAVPAHD+RD EFA ++ LDIIPV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  359  IKPADGSELDISEAAYTEKGVLFDSGEFDGLEFQAAFDAIAAKLEAEGKGTKTVNFRLRD  418
            +  +     ++ EAA+TE G+ ++S+ +DGL+  +A+  +   LEAEG G   V +RLRD
Sbjct  362  LEGG-----NVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  419  WGVSRQRYWGAPIPMVTTEDGEVHPVPADQLPVILP--EDVVMDGVT-SPIKADKEWAKT  475
            W  SRQRYWG PIP++  EDG   +VP  +LP++LP   D+   G   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  476  TF-NGEPALRETDTFDTFMESSWYYARYCSPQADDIL-DPEKANYWLPVDQYIGGIEHAC  533
            T  +G  + RET+T      SSWYY RY  P+  + L D E  + WLPVD Y+GG EHA 
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  534  MHLLYSRFFHKLLRDAGYVTSDEPFKQLLCQGMVLADAFYFENEKGGKEWVAPTDVAVER  593
            +HLLY+RF HK+L D G V + EPF++L+ QGM+L+ +  + + +G+   + +TD    R
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS--YRDSRGA---LVATDKVEKR  591

Query  594  DGKGRIISAKDNEGRDVTHSGMIKMSKSKNNGIDPQEMVDKYGADTVRLFMMFASPADMT  653
            DG   ++     E  + + +   KMSKS +N ++P+++V++YGADT+R++ MF +P D +
Sbjct  592  DGS--FFHVETGEELEQAPA---KMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  654  LEWQESGVEGANRFLKRVWKLVKEHaekgaaeavdaaaLSGEQKALRRDVHKTIAKVTDD  713
            + W E G+EG+ +FL RV +L+                   +  AL +  + T+  VT++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLITTKEIT-----------EENSGALDKVYNETVKAVTEQ  695

Query  714  IARRQTFNTAIAAIMELMNKLAKAPQESAQDRAILDEALKAVVTMLYPITPHISYELWTA  773
            + + + FNTAIA +M ++N        + ++  ++ +  K+ V ++ P++PH++ ELW A
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  774  LGEAD--IDNAAWPTFDEKALVEDEKTIVVQVNGKLRAKLTVAADATKEQVEELGLNDEN  831
            L  ++  I   +WP++DE  LVE++  IVVQ++GK++AKL VA D ++E+++E++L +E+
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  832  VTKFTDGLTIRKVIYVPGKLLNIVAN  857
            V     G  I KVI VP KL+NIV +
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVIK  833

919) leuS in NC_012108


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  557 bits (2101),  Expect = 2e-159, Method: Compositional matrix adjust.
 Identities = 339/842 (41%), Positives = 541/842 (65%), Gaps = 46/842 (5%)

Query  5    YNPEKVEPLWQAYWNQHQTFKATEDGSKPKYYLLEMFPYPSGK-IHMGHVRNYTIGDVVV  63
            Y+   +EP WQA+W +++TFK+  D+SKPK+Y L+MFPYPSG  +H+GH   YT  D++ 
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYKRMKGFNVLHPMGWDAFGMPAENAAIDNNTHPAAWTYENIRTMRRQLKRMGFSYDWDR  123
            R+KR +G NVLHPMGWDAFG+PAE+ A+D   +PA  T ENI   +RQ++ +GFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EIATCRPEYYRWEQWLFLKMLDKDMVYRKESYVNWCDHCQTVLANEQV-EQDMCWRCGKP  182
            E+ T  P+YY+W QW+F K+ +K++ Y  E  VNW ++  T +ANE+V  ++   R G P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VQQKKLWQWFFRITDFAEDLLVHCDKLPGWPDNVTLMQKNWIGKSQGSEIRFPIQGIDEN  242
            V +K ++QW ++IT +AE LL + + + +WP+++  MQ+NWIGKS G+++ F +++ D +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  IPVFTTRPDTLFGSTFMCLAPEHPLVETLSRGTDQAAAVTEFTTRV-LNQERSSIALEKY  301
            + VFTTRPDTLFG+T+  LAPEH+LV++++  +DQA AV+++  +  L+ + +   L K 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAIT-TSDQAEAVADYKRQASLKSDLARTDLAK-  300

Query  302  EKEGVFTGAWCINPVTREKMPIYTANFALMEYGTGAVMSVPAHDQRDFDFARKYGLPIKV  361
            EK GV TG+  INPV    MP+  A++ L  YGTGA+M+VPAHD+RD +FA+++ L I  
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  362  VIQPPGEPLDPATMIEAYTGQGTLADSGEFSGLGNLEAMGAITRWLENKGLGKTTVSFRL  421
            V++  G  ++ A    A+T +G   +S+ + GL++  A++ +  WLE  G+G+  V++RL
Sbjct  361  VLE--GGNVEEA----AFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRL  414

Query  422  RDWGISRQRYWGTPIPVIHCPDCGIVPVKEETLPVVLPEDAAL--LDNGGSPLATLDGFA  479
            RDW +SRQRYWG PIP+IH  D    +V E  LP+VLP    +   + G SPLA + +  
Sbjct  415  RDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTD--  472

Query  480  RVNCPVCNRADARRETDTMDTFVESSWYFARYCSPRYDKGMFDPAAVAYWMPVDQYIGGV  539
            +++    +   +RRET+TM     SSWY+ RY  P+    + D   +  W+PVD Y+GG 
Sbjct  473  WLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGA  532

Query  540  EHAILHLLYSRYFMRVLNTLGLIDFKEPFERLLTQGMVCKETLTCPEHGFIYPDDAETVN  599
            EHA+LHLLY+R+  +VL  LG++  KEPF++L+ QGM+   +   +  +++  D  E  +
Sbjct  533  EHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRD  592

Query  600  DKVICKRCNSDVEVGRVIKMSKSKKNVIDPNALLDQYGADITRLFCLFAAPPEKDLEWND  659
            +  +      ++E +   KMSKS KNV++P+ +++QYGAD  R++ +F +P +  + W++
Sbjct  593  GSFFHVETGEELEQAPA-KMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSE  651

Query  660  DGVEGCNRFINRVWRLADRCKSTYIDLLPYSGVVADLKGEPKKLFIKANQTIKKVTDDIE  719
            +G+EG  +F++RV R           L+    +  +  G   K++   N+T+K VT++++
Sbjct  652  EGLEGSRKFLDRVYR-----------LITTKEITEENSGALDKVY---NETVKAVTEQVD  697

Query  720  ESFHFNTAISAVMELVNAMYSADLDPDQTDMGEVALFC--IENIVLLLSPIVPHFCEELW  777
            +   FNTAI+ +M +VNA    D            LF      +V L++P+ PH+ EELW
Sbjct  698  Q-MKFNTAIAQLMVFVNAANKED-----------KLFSDYAKGFVQLIAPFAPHLGEELW  745

Query  778  SIL-GHGPSIVDQPWPDYQKDALLTDEILIVVQVNGKLRSKFSVDAAVSDDFIRKAALAD  836
              L + G SI   PWP Y+   L+ +++ IVVQ++GK+++K+ V   +S + ++  ALA+
Sbjct  746  QALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALAN  805

Query  837  EQ  838
            E+
Sbjct  806  EK  807

920) Calni_0469 in NC_014758


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  557 bits (2104),  Expect = 9e-160, Method: Compositional matrix adjust.
 Identities = 369/862 (43%), Positives = 551/862 (64%), Gaps = 44/862 (5%)

Query  3    YNPQVIENKWQKVWEENKVFKVEKDNNKPKYYCLEMFPYPSGK-IHMGHVRNYAIGDVIS  61
            Y+   IE KWQ  W +N  FK   D +KPK+Y L+MFPYPSG  +H+GH   Y+  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  62   RYKFMKGFNVIHPMGWDAFGLPAENAAIKNKIHPAKWTYSNIENMKMQLKKMGLSYDWDR  121
            R+K  +G NV+HPMGWDAFGLPAE+ A+    +PA  T  NI N K Q++ +G+SYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  122  EVATCDPEYYKWEQMIFLQMYEKGLVYRKKSLQNWCNDCHTVLANEQV-EDGRCWRCGDI  180
            EV T DP+YYKW Q IF ++YEKGL Y      NW ++  T +ANE+V  DG   R G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  181  VEKKEINSWYFKITDYAEELLDWTYKLPGWPEKVLVMQRNWIGKSYGAEIDFKVEGEPTT  240
            V +K +  W +KIT YAE LL+      +WPE +  MQRNWIGKS GA++ FKV +    
Sbjct  184  VVRKPMRQWMLKITAYAERLLE-DLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  241  ITVFTTRPDTLFGATFMLLAPEHPLSKELLKGTDREKDGFEFI-DGILKEDKISRMADDK  299
            +TVFTTRPDTLFGAT+ +LAPEH+L  + +  +D+     ++  ++ LK D ++R    K
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALV-DAITTSDQAEAVADYKRQASLKSD-LARTDLAK  300

Query  300  EKKGFFTGKYTINPLTGYKMPIYIANYILMDYGTGAVMAVPAHDQRDFEFAKKYNLEIII  359
            EK G  TG Y+INP+ G  MP+ IA+Y+L  YGTGA+MAVPAHD+RD EFAK++NL+II 
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  360  VIKPLDRELDPSKMTE-AYTEPGIMINSGKFDGMNSEEAKTAITDYLLSQSIGKRSVNYR  418
            V       L+ +++ E A+TE G+ INS+ +DG++   A + + + L ++++G+ +V YR
Sbjct  361  V-------LEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYR  413

Query  419  LKDWGISRQRYWGAPIPIIYCDDCGIVPVPYENLPVRLPLDVEFTGIG---NPLDRSESF  475
            L+DW +SRQRYWG PIPII  +D    +VP  +LP+ LP+  ++   G   +PL      
Sbjct  414  LRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDW  473

Query  476  KSVECPKCGKPAVRETDTMDTFVESSWYFLRYCSPKNDKAPFDKDEVKYWMPVDQYIGGV  535
              V      K + RET+TM     SSWY+LRY  P N     D + +K W+PVD Y+GG 
Sbjct  474  LEVTREDGVK-GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGA  532

Query  536  EHAILHLLYSRFYTKVLRDLGYVDFDEPFERLLTQGMVCKETYRCGEHDWLFPEEVVDGK  595
            EHA+LHLLY+RF  KVL DLG V   EPF++L+ QGM+   +YR +    L + + V+ +
Sbjct  533  EHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGA-LVATDKVEKR  591

Query  596  CK---HCGKAVEIGRV-EKMSKSKKNVVDPDNLINEYGADTARLFSLFASPPEKDLEWNE  651
                 H   + E+ +   KMSKS KNVV+PD+++++YGADT R++ +F +P +  + W+E
Sbjct  592  DGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSE  651

Query  652  QGVEGSFRFLGRVWRLIHKNIALFSEELSDNGEESKVSKDILYYMHSAIKKVTLDIEKYQ  711
            +G+EGS +FL+RV RLI  +         +  EE+  + D +Y  + ++K VT ++++ +
Sbjct  652  EGLEGSRKFLDRVYRLITTK---------EITEENSGALDKVY--NETVKAVTEQVDQMK  700

Query  712  LNTAVAAIMEYSNNLSDIEPQIKTDKERYLFREALRSLIILLAPFTPHISEELWNVTGHV  771
            +NTA+A +M + N          ++KE  LF +  ++++ L+APF+PH++EELW+     
Sbjct  701  FNTAIAQLMVFVNA---------ANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTAS  751

Query  772  GLVSRY-EWPTYDDRYTFRDDVTIAIQINGKVRGEIVIQRGSDEGFVLSLAKSDEKIKKY  830
            G    Y  WP+YD+     +DV I +QI+GKV++ +V+ ++     +  +A ++EK++  
Sbjct  752  GESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAE  811

Query  831  LEGKQLVKEIYVKEKLVSFVVK  852
            + GK+++K I V +KLV++V+K
Sbjct  812  IAGKDIIKVIAVPNKLVNIVIK  833

921) GM18_3598 in NC_014973


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  556 bits (2100),  Expect = 2e-159, Method: Compositional matrix adjust.
 Identities = 363/858 (43%), Positives = 540/858 (63%), Gaps = 68/858 (7%)

Query  5    YVPSAVEGKWQQFWATHDSFKATEDASRKKYYLLEMFPYPSGK-IHMGHVRNYSIGDVIA  63
            Y  +A+E KWQ FWA +++FK+  DAS+ K+Y L+MFPYPSG  +H+GH   Y+  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RFKRMQGYNVLHPMGWDAFGMPAENAAIQNKSHPAKWTYENIAYMRGQLKRLGLSYDWDR  123
            RFKR QG NVLHPMGWDAFG+PAE+ A++  ++PA  T ENIA  + Q++ LG+SYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCDLDYYKWEQKIFLEMYRKGLAYKKSSAVNWCPKCETVLANEQV-EDGCCWRCDAI  182
            E+ T D +YYKW Q IF  +Y KGLAY    +VNW     T +ANE+V  DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VQQKELEQWSFRITNYAQELLDDTYKLAGWPERVLTMQRNWIGRSVGCEIDFPLENGLSK  242
            V +K + QW ++IT YA+ LL+D     +WPE +  MQRNWIG+S G ++ F + +    
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDL-EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  VKVFTTRQDTLFGATFMSLAAEHPMALDLASAEQRAEVVAFIEKVKKTDRIKRSAEDLEK  302
              VFTTR DTLFGAT+  LA+EH++   +++++Q   V  +  +      + R+    EK
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEK  302

Query  303  EGVFTGSYCVNPVTNARMPIYLANFVLMDYGTGAVMAVPTHDQRDFEFASKYNLPLKVVI  362
             GV TGSY +NPV    MP+ +A++VL  YGTGA+MAVP+HD+RD EFA ++NL +  V+
Sbjct  303  TGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL  362

Query  363  QPEGETLDPAAMAEAYTADGIMVNSGRFDGMGNADAKEAIADFLEKEGIGKKTVNFRLRD  422
              EG  ++ A    A+T DG+ +NS+ +DG+++A A   + + LE EG+G+  V +RLRD
Sbjct  363  --EGGNVEEA----AFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  423  WGISRQRYWGNPIPVINCDLCGVVAVPEADLPVVLPMDAEF--TGEGGNPLARVESFTNC  480
            W +SRQRYWG+PIP+I+ +     AVPE++LP+VLP+  ++  +G G +PLA V    + 
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  481  TCPQCGEAASRETDTMDTFVQSSWYFLRYCSPKFTAGPLDREQVEAWMPVDQYIGGIEHA  540
            T  + G  + RET+TM     SSWY+LRY  P  T    D E +  W+PVD Y+GG EHA
Sbjct  477  TRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  541  VLHLLYARFFTKVLRDLGYCNVDEPFSNLLTQGMVI-------------------KDG--  579
            VLHLLYARF  KVL DLG     EPF +L+ QGM++                   +DG  
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSF  595

Query  580  -------------AKMSKSKGNVVDPNALIERYGADTARLFSLFAAPPEKDLDWSDQGVD  626
                         AKMSKS  NVV+P+ ++E+YGADT R++ +F +P +  + WS++G++
Sbjct  596  FHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLE  655

Query  627  GSYRFLNRVWRLVFDVLPAIKGAGSVETDKLSAEGKNLRRAVHKTIKKVSEDIEERFHFN  686
            GS +FL+RV RL+               +    ++  L +  + T+K V+E++++   FN
Sbjct  656  GSRKFLDRVYRLI------------TTKEITEENSGALDKVYNETVKAVTEQVDQ-MKFN  702

Query  687  TAIAAVMELVNAIQAFSAKAAPENVAVVREAMESVARLLAPFVPHFAEELWAEL-GHETG  745
            TAIA +M +VN        AA  +  +  +   +  +L+APF PH++EELW  L +   +
Sbjct  703  TAIAQLMVFVN--------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGES  754

Query  746  LEQAGWPGYdadavvdeevtvvIQVNGKLRSKLTVAPDAKEEEVRSAALADDKIKPYLEG  805
            +    WP+YD   +V+++V +V+Q++GK+++KL VA D   EE++  ALA++K+++ + G
Sbjct  755  ISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAG  814

Query  806  KSVKKVVYVPGKLVSIVV  823
            K + KV+ VP KLV+IV+
Sbjct  815  KDIIKVIAVPNKLVNIVI  832

922) leuS in NC_021848


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  556 bits (2100),  Expect = 2e-159, Method: Compositional matrix adjust.
 Identities = 372/866 (43%), Positives = 559/866 (65%), Gaps = 49/866 (5%)

Query  5    YNPQDIEQKVQKHWDDNKTFVVSEDPNKEKFYCLSMFPYPSGR-LHMGHVRNYTIGDVVS  63
            Y+   IE K Q  W DN TF  + D++K KFY L MFPYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RFQRLQGKNVMQPIGWDAFGLPAENAAVKNNTAPAPWTYENIEYMKNQLKLLGFGYDWNR  123
            RF+R QG NV++P+GWDAFGLPAE+ A+     PA  T ENI   K Q++ LGF+YDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EFATCTPEYYRWEQEFFTKLYEKGLVYKKTSSVNWCPNDQTVLANEQV-EDGCCWRCDTP  182
            E  T  P+YY+W Q +FTKLYEKGL Y    +VNW  +  T +ANE+V  DG   R + P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VEQKEIPQWFIKITEYAQELLDDLDKLEGWPEMVKTMQRNWIGRSEGVELKFEVKG-QQD  241
            V +K + QW +KIT YA+ LL+DL+ ++ WPE +K MQRNWIG+S G ++ F VK+ ++D
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  242  LEVYTTRPDTLMGVTYVGIAAGHPL--ATLAAENNPELAAFI-EECKNTKVAEAELATME  298
            + V+TTRPDTL G TY  +A+ H+L  A  ++++   +A +  +   ++ +A ++LA  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  299  KKGMATGLTAIHPLNGREVPVYVANFVLMDYGTGAVMAVPAHDQRDFEFATKYGLDIIPV  358
            K G+ TG  AI+P+NG+E+PV +A++VL  YGTGA+MAVPAHD+RD EFA ++ LDIIPV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  359  IKPADGSELDISEAAYTEKGVLFDSGEFDGLEFQAAFDAIAAKLEAEGKGTKTVNFRLRD  418
            +  +     ++ EAA+TE G+ ++S+ +DGL+  +A+  +   LEAEG G   V +RLRD
Sbjct  362  LEGG-----NVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  419  WGVSRQRYWGAPIPMVTTEDGEVHPVPADQLPVILP--EDVVMDGVT-SPIKADKEWAKT  475
            W  SRQRYWG PIP++  EDG   +VP  +LP++LP   D+   G   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  476  TF-NGEPALRETDTFDTFMESSWYYARYCSPQADDIL-DPEKANYWLPVDQYIGGIEHAC  533
            T  +G  + RET+T      SSWYY RY  P+  + L D E  + WLPVD Y+GG EHA 
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  534  MHLLYSRFFHKLLRDAGYVTSDEPFKQLLCQGMVLADAFYFENEKGGKEWVAPTDVAVER  593
            +HLLY+RF HK+L D G V + EPF++L+ QGM+L+ +  + + +G+   + +TD    R
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS--YRDSRGA---LVATDKVEKR  591

Query  594  DGKGRIISAKDNEGRDVTHSGMIKMSKSKNNGIDPQEMVDKYGADTVRLFMMFASPADMT  653
            DG   ++     E  + + +   KMSKS +N ++P+++V++YGADT+R++ MF +P D +
Sbjct  592  DGS--FFHVETGEELEQAPA---KMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  654  LEWQESGVEGANRFLKRVWKLVKEHaekgaaeavdaaaLSGEQKALRRDVHKTIAKVTDD  713
            + W E G+EG+ +FL RV +L+                   +  AL +  + T+  VT++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLITTKEIT-----------EENSGALDKVYNETVKAVTEQ  695

Query  714  IARRQTFNTAIAAIMELMNKLAKAPQESAQDRAILDEALKAVVTMLYPITPHISYELWTA  773
            + + + FNTAIA +M ++N        + ++  ++ +  K+ V ++ P++PH++ ELW A
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  774  LGEAD--IDNAAWPTFDEKALVEDEKTIVVQVNGKLRAKLTVAADATKEQVEELGLNDEN  831
            L  ++  I   +WP++DE  LVE++  IVVQ++GK++AKL VA D ++E+++E++L +E+
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  832  VTKFTDGLTIRKVIYVPGKLLNIVAN  857
            V     G  I KVI VP KL+NIV +
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVIK  833

923) leuS in NC_017550


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  556 bits (2099),  Expect = 2e-159, Method: Compositional matrix adjust.
 Identities = 352/853 (42%), Positives = 536/853 (63%), Gaps = 60/853 (7%)

Query  11   YDAVAAQEKWSKYWEEHRTFASLDDGSRERRYVLDMFAYPSG-DLHMGHAEAFAIGDVLA  69
            YD  A + KW  +W +++TF +  D+S+ + Y LDMF+YPSG +LH+GH+E+++  D+L+
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  70   RYWRLRGFDVLHPVGWDSFGLPAENAAIKHGTHPAEWTYRNIDTQAASFKRYAVSFDWSM  129
            R+ R +G +VLHP+GWD+FGLPAE+ A+  G +PAE T  NI      ++  + S+DW  
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  130  RLHTSDEEYYRWTQWLFNRFFEKGLAYRKDSWANWCPIDQTVLANEQV-KDGCCERCGAV  188
             ++T+D +YY+WTQW+F +++EKGLAY  +   NW     T +ANE+V  DG  ER G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  189  VTKRQLNQWYFRITDYAQRLLDDMDQIEGKWPERVLSMQRNWIGRSEGAYVDFTIDDHKE  248
            V ++ + QW ++IT YA+RLL+D+++++  WPE +  MQRNWIG+S GA V F + D   
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD--WPESIKDMQRNWIGKSTGANVTFKVKDTDK  241

Query  249  PVRVFTTRPDTLYGATFMVVAPDSALAQEIVSDEARPAFETYLDEVKKKSEIERQATDHE  308
               VFTTRPDTL+GAT+ V+AP+ AL + I + +   A   Y  +   KS++ R     E
Sbjct  242  DFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKE  301

Query  309  KTGVPLGVEATNPVNGAKVPVWAGDYVLADYGTGAVMAVPAHDQRDLDFARTYGIDVIPV  368
            KTGV  G  A NPVNG  +PVW +DYVLA YGTGA+MAVPAHD+RD +FA+ + +D+IPV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  369  IDTGEADPRESGVATTGDGVYQNSGFLNGIATKAEAIAKMCEFLDEKGIGEPTITYRLRD  428
            ++ G+ +      A T DG+  NS+FL+G+  KA AIAKM E L+  G+G+  +TYRLRD
Sbjct  362  LEGGNVE----EAAFTEDGLHINSDFLDGLD-KASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  429  WLLSRQRFWGCPIPIIHCESCGDVPVPDEQLPVKLPDLRGAELAPKGTSPLAGEEASEWR  488
            WL+SRQR+WG PIPIIH E     +VP+ +LP+ LP  ++   +  G SPLA  + ++W 
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLA--NVTDWL  474

Query  489  SVACPSCGGAAQRDTDTMDTFVDSSWYFMRYCCPHYDKGPFDVEAVRRWMPVAQYIGGVE  548
             V+    G  ++R+T+TM    +SSWY++RY  PH      D E +++W+PV  Y+GG E
Sbjct  475  EVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAE  533

Query  549  HATMHLLYSRFFTKVLYDLGMVDFTEPFQRLMNQGQVIN----EGRA-------------  591
            HA +HLLY+RF  KVLYDLG+V   EPFQ+L NQG ++     ++R+             
Sbjct  534  HAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDG  593

Query  592  -----------------MSKSLGNGVDLGKQIDEFGVDAVRTTVIFAGPPDEDIDWADVS  634
                             MSKSL N V+ +  ++++G D++R   +F GP D  I W++ +
Sbjct  594  SFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEG  653

Query  635  PASTLKFLQRAWRVAAEVTSDPDADLTQGDSTLRRVTHRSIADITELLEGGRYNVVVARI  694
              ++ KFL+R  R+   +T+   ++  +  ++L +V + ++  +TE ++  ++N  +A++
Sbjct  654  LEGSRKFLDRVYRL---ITTKEITE--ENSGALDKVYNETVKAVTEQVDQMKFNTAIAQL  708

Query  695  MELVNATRKAIDSGCGPADPAVREAVTFTAQALSLVAPYLAEEMWEML-GLEPSVANSHW  753
            M +VNA+ K      + A   V+    F        AP L+EE+W+ L +   S++   W
Sbjct  709  MVFVNAANKEDKLFSDYAKGFVQLIAPF--------APHLGEELWQALTASGESISYVPW  760

Query  754  PTADEKLLVADKVTMVVQVTGKVRAKLTVSPDITEAEAREVALADVNVQRFTEGKEIVKI  813
            P+ DE  LV + V +VVQ+ GKV+AKL V+ D++  E +EVALA+ +VQ    GK+I+K+
Sbjct  761  PSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKV  820

Query  814  IAKLPKMISIVAK  826
            IA   K+++IV K
Sbjct  821  IAVPNKLVNIVIK  833

924) leuS in NC_010519


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  556 bits (2100),  Expect = 2e-159, Method: Compositional matrix adjust.
 Identities = 353/868 (41%), Positives = 569/868 (66%), Gaps = 50/868 (5%)

Query  5    YRPDLIEADVQKYWAEKKTFKAVKDPFKEKYYCLSMFPYPSGR-LHMGHVRNYTIGDVIS  63
            Y    IE+  Q +WA++ TFK+  D+ K K+Y L MFPYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMNGKNVLQPMGWDAFGLPAEGAAIKNKTAPAKWTYENIEYMKNQLKVLGFGFDWDR  123
            R++R +G NVL+PMGWDAFGLPAE  A+     PA  T ENI   K Q++ LGF++DWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EITTCKPEYYKWEQWFFTELYKKGLVYKKTSTVNWCPNDETVLANEQV-HEGGCWRCDTP  182
            E+ T  P+YYKW QW+FT LY KGL Y     VNW  +  T +ANE+V  +G   R + P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VEQKEIPQWFIKITDYAEQLLSDLDQLPEWPDMVKTMQRNWIGRSEGVEITFNVAHSDQT  242
            V +K + QW +KIT YAE+LL DL+++ +WP+ +K MQRNWIG+S G ++TF+V ++D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFYGVSYLAVAAAHPLAENAAKNNP--ELAAFIHEAK-NTKVAEAELATME  299
            +TV+TTRPDT++G +Y  +A+ H+L +  + ++    +A + ++A  ++ +A ++LA  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGMATGLYAVHPMTGKQLPIWVANFVLMHYGTGAVMAVPAHDQRDYEFAQKYQLPLFPV  359
            K G+ TG YA++P+ GK++P+W+A++VL  YGTGA+MAVPAHD+RD EFA++++L ++PV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  360  IKPADNSAWDFSKQAYTEHGITINSAEFDGLDFEATFNGIADKLEKIGVGKRQVNYRLRD  419
            +  ++         A+TE+G+ INS  +DGLD  +++  + + LE  GVG+ +V YRLRD
Sbjct  362  LEGGNVEE-----AAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMLTLENGDVVVAPLQDLPIVLP--EDVVMDGV-KSPIKADPEWAKT  476
            W  SRQRYWG PIP++  E+G     P  +LP+VLP   D+   G   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  TYNGQV-ALKETDTFDTFMESSWYYARYTSPQYQQAMLDADETNYWLPVDQYIGGIEHAT  535
            T ++ V + +ET+T      SSWYY RY  P+  + + D +  + WLPVD Y+GG EHA 
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLLYFRFFHKLLRDAGFVTSDEPSKKLLCQGMVLADAFYYTSPTNERIWVSPTKVTLER  595
            +HLLY RF HK+L D G V + EP +KL+ QGM+L+ ++      + R     + V+ ++
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSR----GALVATDK  587

Query  596  DEK--GRIIKAVDDEGHELVHSGMTKMSKSKNNGIDPQEMVEKYGADTVRLFMMFASPAE  653
             EK  G ++    + G+EL ++  +KMSKS +N ++P+++VE+YGADT+R++ MF +P +
Sbjct  588  VEKRDGSFFHV--ETGEELEQAP-AKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLD  644

Query  654  MTLEWQESGVEGANRFLRRLWNLVFEYNQNPAQTALDPTALSVEQKALRREVHKTIAKVS  713
             ++ W E G+EG+ +FL R+  L+        + + + ++      AL +  + T+  V+
Sbjct  645  ASIAWSEEGLEGSRKFLDRVYRLI-----TTKEITEENSG------ALDKVYNETVKAVT  693

Query  714  DDIGRRQTFNTAIAAIMELMNKLTKASLSNEQDRAVMAEALNAVVRMLYPITPHICFQLW  773
            +++++ + FNTAIA +M ++N       + +++  + ++  ++ V+++ P++PH+  +LW
Sbjct  694  EQVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELW  745

Query  774  QDL-GNESAIDFAPWVIADAEAMVEDEKLVVIQVNGKVRAKVTVPADMSEDEIKQVALAE  832
            Q L ++  +I + PW   D   +VE++  +V+Q++GKV+AK+ V+ D+S +E+++VALA+
Sbjct  746  QALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALAN  805

Query  833  ENVQKFLNGLTVVKTIYVPGKLFSFVAK  860
            E+VQ  + G  ++K I VP KL ++V K
Sbjct  806  EKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

925) leuS in NC_008541


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  556 bits (2098),  Expect = 3e-159, Method: Compositional matrix adjust.
 Identities = 357/857 (42%), Positives = 547/857 (64%), Gaps = 68/857 (7%)

Query  24   YSFAAMEAKWPQVWEDLKVFTPVDDGSRERRYVLDMFPYPSG-DLHMGHAEAFAMGDVVA  82
            Y  +A+E+KW   W D   F    D+S+ + Y LDMFPYPSG +LH+GH+E+++  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  83   RYLRQKGYDVLHPIGWDSFGLPAENAAIKRNAHPSEWTYANIDTQAASFKRYAISADWSR  142
            R+ R +G +VLHP+GWD+FGLPAE+ A+    +P+E T  NI      ++  ++S DW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  143  RLHTSDPEYYRWTQWLFKRFYERGLAYRKDSPVNWCPKDQTVLANEQVV-NGACERCGTA  201
             ++T+DP+YY+WTQW+F ++YE+GLAY  + PVNW     T +ANE+V+ +G+ ER G +
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  202  VTKKSLNQWYFKITDYADRLLDDMDELRGHWPERVLAMQKNWIGRSEGAHVNFVIEAAGD  261
            V +K++ QW +KIT YA+RLL+D++E+  +WPE +  MQ+NWIG+S GA+V F +  ++ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV--DWPESIKDMQRNWIGKSTGANVTFKVKDTD-  240

Query  262  KPAKDVTVFTTRPDTLYGATFFVVAADAPMAVELVTDEHAAALDAYREQVKALSEIERQS  321
               KD TVFTTRPDTL+GAT+ V+A++ ++   + T ++A A+  Y+ Q    S++ R  
Sbjct  241  ---KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTD  297

Query  322  TEREKTGVFTGRYAVNPLNGEKLPVWAADYVLADYGTGAIMAVPAHDQRDLDFARTFDLP  381
              +EKTGV TG YA+NP+NG  +PVW ADYVLA YGTGAIMAVPAHD+RD +FA+ F+L 
Sbjct  298  LAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLD  357

Query  382  VRAVLDTGEDDPAVTGKATAGEGTLINSGVLDGLPKAEAIPTAIDMLEKQGTGEKFVNFR  441
            + +VL+ G+    V   A + +G  INS+ LDGL KA AI+  ++ LE +G G+  V +R
Sbjct  358  IIPVLEGGN----VEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYR  413

Query  442  LRDWLLSRQRFWGTPIPIIHCPACGEVPVPDDQLPVTLPADLRGEDLSPKGT--SPLAAA  499
            LRDWL+SRQR+WG PIPIIH       +VP+ +LP+ LP      D+ P GT  SPLA  
Sbjct  414  LRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPV---TKDIRPSGTGESPLANV  470

Query  500  EAWVNVECPNCHGPAKRDTDTMDTFVDSSWYFLRFVSPQYTEGPFDPKKINDWMPVGQYV  559
              W++V   +    ++R+T+TM    +SSWY+LR++ P+ TE   D   +++W+PV+ YV
Sbjct  471  TDWLEVTREDG-VKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYV  529

Query  560  GGVEHAILHLLYARFFTKVIHDLGMIDADEPFSALLNQGQVLNGG---------------  604
            GG EHA+LHLLYARF  KV+ DLG++ + EPF  L+NQG +L  +               
Sbjct  530  GGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVE  589

Query  605  -------------------KAMSKSLGNGVDLGEQLDKYGVDAVRLTMIFASPPEDDVDW  645
                                 MSKSL N V+ ++ +++YG D++R+  +F +P +  + W
Sbjct  590  KRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAW  649

Query  646  ADVSPSGSAKFLARAWRLAQDVSSAPGADAAQGDRALRSVTHRTIADAAALLDSNKFNVV  705
            ++ +  GS KFL R  RL   +++   ++   G  AL  V + T+   +  +D  KFN  
Sbjct  650  SEEGLEGSRKFLDRVYRL---ITTKEITEENSG--ALDKVYNETVKAVTEQVDQMKFNTA  704

Query  706  VAKLMELVNATRKTIDaasgaggaDPavreaaeavavILSLFAPYTAEDMWNVLGHPA-S  764
            +A+LM +VNA+ K           D    + A +   +++ FAP  +E++W+ L  ++ S
Sbjct  705  IAQLMVFVNAANKE----------DKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGES  754

Query  765  VANAGWPSHDEallvqdtvtavvqvQGKVRDRLEVSPEIGEDELRELALASENVQRALDG  824
            ++   WPS DE+ LV++ V  VVQ++GKV+ +L V+ +++ +EL+E+ALA+E+VQ  + G
Sbjct  755  ISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAG  814

Query  825  RGIRTVIVRAPKLVNIV  841
            ++I  VI  + KLVNIV
Sbjct  815  KDIIKVIAVPNKLVNIV  831

926) leuS in NC_007517


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  555 bits (2097),  Expect = 3e-159, Method: Compositional matrix adjust.
 Identities = 367/859 (43%), Positives = 543/859 (64%), Gaps = 70/859 (8%)

Query  5    YIPRNVEEKWQKIWEENKTYKVTEDPSKPKYYLLEMFPYPSGR-IHMGHVRNYSIGDVVG  63
            Y    +E KWQ +W +N T+K   D+SKPK+Y L+MFPYPSG  +H+GH   Y+  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RFKRLRGFNVLHPMGWDAFGMPAENAAIQHKSHPAKWTYENIAYMRSQLKKMGLSYDWDR  123
            RFKR +G NVLHPMGWDAFG+PAE+ A++  ++PA  T ENIA  + Q++ +G+SYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCDLDYYKWEQKVFLEMYEKGLAYKKTSYVNWCPKCETVLANEQV-EDGACWRCDSE  182
            E+ T D +YYKW Q +F  +YEKGLAY     VNW     T +ANE+V  DG+  R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VTQKELEQWFFRITDYAEELLEYTEKLPGWPERVLTMQRNWIGKSYGCEIDFPVEGSLAK  242
            V +K + QW ++IT YAE LLE  E + +WPE +  MQRNWIGKS G ++ F V ++   
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  IKVFTTRQDTLYGATFMSLAPEHPMALELTTPDRRAEVEAFIDKVKKTDKIKRTAEDFEK  302
            + VFTTR DTL+GAT+  LAPEH++   +TT+D+   V  +  +      + RT    EK
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEK  302

Query  303  EGVFTGSYCINPVTNRRMPVFLANFVLLDYGTGAVMAVPTHDQRDFEFARKYDLPLQVVI  362
             GV TGSY INPV  + MPV +A++VL  YGTGA+MAVP+HD+RD EFA++++L +  V+
Sbjct  303  TGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL  362

Query  363  QPEGETLDPAAMATAYTEVGTMVNSGTFDGLRSDEAKEKIADYLAKEGIGTKTVNFRLRD  422
              EG  ++     +A+TE G  +NS+ +DGL    A  K+ + L  EG+G   V +RLRD
Sbjct  363  --EGGNVE----EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  423  WGISRQRYWGNPIPVIYCDICGVVPVPEKDLPVVLPMDVEF--TGEGGSPLKKLDSFVNV  480
            W +SRQRYWG+PIP+I  +     +VPE +LP+VLP+  ++  +G G SPL ++   ++V
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  481  PCPQCGQMARRETDTMDTFVQSSWYFLRYCCPDFAAGPIDKARAEYWMSVDQYIGGIEHA  540
               + G  +RRET+TM     SSWY+LRY  P+ +    D      W++VD Y+GG EHA
Sbjct  477  -TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  541  VLHLLYARFFTKALRDLGYVTVDEPFTNLLTQGMVI-------------------KDG--  579
            VLHLLYARF  K L DLG V   EPF +L+ QGM++                   +DG  
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSF  595

Query  580  -------------AKMSKSKGNVVDPDALINRYGADTARLFSLFAAPPEKDLDWSDQGVD  626
                         AKMSKS  NVV+PD ++++YGADT R++ +F +P +  + WS++G++
Sbjct  596  FHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLE  655

Query  627  GSYRFLSRVWRLVCDLLPFVGKGGAVDSASLSDDARG-LRRAVHKTIRKVTDDIDERFHF  685
            GS +FL RV RL+              +  ++++  G L +  + T++ VT+++D+   F
Sbjct  656  GSRKFLDRVYRLIT-------------TKEITEENSGALDKVYNETVKAVTEQVDQ-MKF  701

Query  686  NTAIAAIMELVNAIYAFEPKNAPENGPVLTEAIESVVIMLSPFVPHVTEELWEALGHQG-  744
            NTAIA +M +VNA        A  ++ ++++   + V +++PF PH+ EELW+AL   G 
Sbjct  702  NTAIAQLMVFVNA--------ANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGE  753

Query  745  GVEAAGWPSFDPSAAVDEEFLIVVQVNGKLRGKVTVATDATEEQVKAAAFADEKVKPWIE  804
            ++    WPS+D S  V+++  IVVQ++GK+++K+ VA D + E+++  A+A+EKV++ I 
Sbjct  754  SISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIA  813

Query  805  GKQLRKAIYVPGKLLNIVV  823
            GK++ K I VP KL+NIV+
Sbjct  814  GKDIIKVIAVPNKLVNIVI  832

927) leuS in NC_008751


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  555 bits (2097),  Expect = 3e-159, Method: Compositional matrix adjust.
 Identities = 363/865 (42%), Positives = 538/865 (63%), Gaps = 75/865 (8%)

Query  3    YDHQSIETRWQKKWEDSGIFQCDTEADKPKYYVLEMFPYPSG-NIHMGHVRNYSIGDVVA  61
            YDH +IE +WQ  W D+  F+ +T+A KPK+Y L+MFPYPSG  +H+GH   Y+  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  62   RFKRMQGFNVLHPMGWDAFGLPAENAAIKNGTHPAKWTFANIDNMRSQLKRLGYSYDWQR  121
            RFKR QG NVLHPMGWDAFGLPAE+ A+  G +PA  T  NI N + Q++ LG+SYDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  122  EVATCTPEYYRWEQLFFLRFLEKGLVYRKKAAQNWCPKCHTVLANEQVI-EGLCWRCDSA  180
            EV T  P+YY+W Q +F ++ EKGL Y    + NW     T +ANE+V+ +G   R + +
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  181  VEQKELTQWFLRITDYAEELLADLSKLENGWPERVLSMQRNWIGKSTGAEIRFALDGRDD  240
            V +K + QW L+IT YAE LL DL  ++  WPE +  MQRNWIGKSTGA++ F + + D 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD--WPESIKDMQRNWIGKSTGANVTFKVKDTDK  241

Query  241  SITVFTTRPDTIFGATFMSIAPEHPLVEELIDGKPQADDVRAFVERIRNMDRIDRQSDTL  300
             +TVFTTRPDT+FGAT+  +APEH+LV+  I    QA+ V  +  +      + R   + 
Sbjct  242  DFTVFTTRPDTLFGATYAVLAPEHALVDA-ITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  301  EKEGVFTGAYCVNPFTGRKMPIWVANFVLAEYGTGAVMAVPAHDQRDFEFARKYDLPMQV  360
            EK GV TG+Y +NP  G+ MP+W+A++VLA YGTGA+MAVPAHD+RD EFA++++L +  
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  361  VIQPQGETLDPATMSAAWTEAGALVNSGNFDGLANEDAKQRIADDLETTGNGRRTINYRL  420
            V+  +G  ++ A+     TE G  +NS+ +DGL +  A  ++ + LE+ G G   + YRL
Sbjct  361  VL--EGGNVEEAAF----TEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRL  414

Query  421  RDWNISRQRYWGAPIPVIYCDACGVVPEKEENLPVVLPL--DVKTHDDGRSPLPHTPAFY  478
            RDW +SRQRYWG PIP+I  +     +  E +LP+VLP+  D++  + G SPL++     
Sbjct  415  RDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWL  474

Query  479  ECTCPVCGGKARRETDTMDTFVESSWYFARYTDATNDKAPFTPDALRYWLPVDQYIGGVE  538
            E T    G K+RRET+TM     SSWY+ RY D+ N       + L+ WLPVD Y+GG E
Sbjct  475  EVTRE-DGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAE  533

Query  539  HAILHLLYSRFFTKALRDCGFIELDEPFANLLTQGMVL----------------------  576
            HA+LHLLY+RF  K L D G +   EPF +L+ QGM+L                      
Sbjct  534  HAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDG  593

Query  577  ------------MDGSKMSKSKGNVVDPTEMIARYGADTVRLFCLFAAPPERDFDWSESG  624
                           +KMSKS  NVV+P +++ +YGADT+R++ +F +P +  + WSE G
Sbjct  594  SFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEG  653

Query  625  IEGSYRFVGRVWRLVEELREHLLAVGACSSTAEDAKTPVARELRLKEHATVRKAGDDLND  684
            +EGS +F++RV RL+           +    +E+   ++ +      + TV+   +++ D
Sbjct  654  LEGSRKFLDRVYRLI-----------TTKEITEENSGALDKVY----NETVKAVTEQV-D  697

Query  685  RFQFNTAIAAVMELVNALYLAKDELVADESGRKvlssavstvltllsPFTPHLSEELW-A  743
            + +FNTAIA +M +VNA    K++ +  + ++          + L++PF+PHL+EELW A
Sbjct  698  QMKFNTAIAQLMVFVNA--ANKEDKLFSDYAK--------GFVQLIAPFAPHLGEELWQA  747

Query  744  LLGHTESVSTLPWPRWKEDALVRDTVTLVVQVNGKLRGKLDIPADASREEVETLALNEPN  803
            L +  ES+S +PWP   E  LV + V +VVQ++GK+++KL ++ D SREE++ +AL + +
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  804  VLRYLEGVTVRKVVVIPGKLVNVVV  828
            V   + G  + KV+ +P KLVN+V+
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVI  832

928) Lebu_0511 in NC_013192


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  555 bits (2096),  Expect = 4e-159, Method: Compositional matrix adjust.
 Identities = 370/871 (43%), Positives = 550/871 (64%), Gaps = 73/871 (8%)

Query  5    YKPSEIEKKWQDKWFEEDVFKSENKIEGKENYYVLEMFAYPSGK-LHVGHLRNYAIGDAI  63
            Y  + IE KWQ  W +++ FK+     +K ++Y L+MF+YPSG  LHVGH   Y+  D +
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTD-ASKPKFYALDMFPYPSGAGLHVGHPEGYTATDIL  62

Query  64   ARYKKMKGFNVLHPFGWDSFGLPAENAAIDNGAHPGKWTKANIDNMRRQMKLMGLSYDWN  123
            +R+K+ +G NVLHP GWD+FGLPAE+ A+D G +P+  T  NI N +RQ++ +G+SYDW+
Sbjct  63   SRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWD  122

Query  124  RELSTYTPEYYKWNQKFFIEMYKKGLVYKKKSYVNWCPDCNTVLANEQV-EDGKCWRHGK  182
            RE++T  P+YYKW Q +F  +Y KGL Y     VNW  +  T +ANE+V  DG    +G 
Sbjct  123  REVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTS-ERGG  181

Query  183  TDVIQKELSQWYFKITEYAEELLQGHEELRGHWPEQVLTMQKNWIGKSTGSEVDFILDYK  242
              V++K + QW +KIT YAE LL++ EE+  +WPE +  MQ+NWIGKSTG++V F     
Sbjct  182  YPVVRKPMRQWMLKITAYAERLLEDLEEV--DWPESIKDMQRNWIGKSTGANVTF-----  234

Query  243  FENDGNSHLKLNDNGEVVISVFTTRPDTLYGVTYATVAPEHPLVEEIILKENPSIREAVE  302
                     K++D  +  ++VFTTRPDTL+G TYA +APEH+LV+ I   +++       
Sbjct  235  ---------KVKDT-DKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYK  284

Query  303  RMIN-EDKIARTAEDKEKEGVFSGLYVINPVNGEKVQLWIANYVLMDYGTGAVMAVPAHD  361
            R  +    +ART   KEK GV +G Y INPVNG  + +WIA+YVL  YGTGA+MAVPAHD
Sbjct  285  RQASLKSDLARTDLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHD  344

Query  362  ERDFQFSKKYNLDLKIVVNPVDKNGNLEEVSVEKIENALVNSGVLVNSEEFNGLNSNEAK  421
            ERD +F+K++NLD    + PV   GN+EE        A+ + G+ +NS+ ++GL+   A 
Sbjct  345  ERDWEFAKQFNLD----IIPVLEGGNVEE-------AAFTEDGLHINSDFLDGLDKASAI  393

Query  422  EKITEKLEKIGLGKKTVNYRLHDWLISRQRYWGTPIPVIYDEDGNIYLEEEANLPVKLPT  481
             K+ E LE  G+G+  V YRL+DWL+SRQRYWG PIP+I  EDG      E++LP+ LP 
Sbjct  394  AKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPV  453

Query  482  DIEFSGKG---NPLETSEEFKNVILPNGKKGRRETDTMDTFVDSSWYYLRYLDSHNDKEP  538
              ++   G   +PL    +  +V   +G KGRRET+TM    +SSWYYLRY+D+HN    
Sbjct  454  TKDIRPSGTGESPLANVTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKL  513

Query  539  FKKEDADNWTPVHQYIGGIEHAVMHLLYARFFHKSLRDLGYVDTNEPFKRLLTQGMVLGP  598
               E   +W PV+ Y+GG EHAV+HLLYARF HK L DLG V T+EPF++L+ QGM+LG 
Sbjct  514  ADEELLKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGT  573

Query  599  SYYSQNERRYLFPRE-VEMKDGKPVSKETGEELATKVEKMSKSKNNGVDPEEIVKEYGSD  657
            SY  ++ R  L + + VE +DG     ETGEEL     KMSKS +N V+P+++V +YG+D
Sbjct  574  SY--RDSRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGAD  631

Query  658  SSRVFTLFAAPPEKELEWNMNGLAGAYRFINRLYLLISSTADFADKNVSKENNYGINLDA  717
            + RV+ +F +P +  + W+ +GL G+ +F++R+Y LI++      K+++ EN+       
Sbjct  632  TLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITT------KEITEENS-------  678

Query  718  RSEKDKEIQKKLHQTVKKVTDSIEDDFHFNTAIAAIMELLNDMTTYKQNVIDKNDISSES  777
                   ++K  ++TVK VT+ + D+  FNTAIA +M ++N               ++  
Sbjct  679  -----GALDKVYNETVKAVTEQV-DQMKFNTAIAQLMVFVNA--------------ANKE  718

Query  778  KKVWHEVLEKVILLIAPFAPHVADELWSDLGNTTLTFE-EEWPAFDEKLTVENNFNLVLQ  836
             K+  +     + LIAPFAPH+++ELW  L  +  ++    WP++DE   VEN+ ++V+Q
Sbjct  719  DKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQ  778

Query  837  VNGKVRDMLPAQIGISKDDAEKLAFSSEKVQ  867
            ++GKV+  L    ++S+++ + +A+++EKVQ
Sbjct  779  IKGKVKAKLVVAKDLSREELQEVALANEKVQ  809

929) leuS in NC_002937


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  555 bits (2096),  Expect = 4e-159, Method: Compositional matrix adjust.
 Identities = 363/865 (42%), Positives = 538/865 (63%), Gaps = 75/865 (8%)

Query  3    YDHQSIETRWQKKWEDSGIFQCDTEADKPKYYVLEMFPYPSG-NIHMGHVRNYSIGDVVA  61
            YDH +IE +WQ  W D+  F+ +T+A KPK+Y L+MFPYPSG  +H+GH   Y+  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  62   RFKRMQGFNVLHPMGWDAFGLPAENAAIKNGTHPAKWTFANIDNMRSQLKRLGYSYDWQR  121
            RFKR QG NVLHPMGWDAFGLPAE+ A+  G +PA  T  NI N + Q++ LG+SYDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  122  EVATCTPEYYRWEQLFFLRFLEKGLVYRKKAAQNWCPKCHTVLANEQVI-EGLCWRCDSA  180
            EV T  P+YY+W Q +F ++ EKGL Y    + NW     T +ANE+V+ +G   R + +
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  181  VEQKELTQWFLRITDYAEELLADLSKLENGWPERVLSMQRNWIGKSTGAEIRFALDGRDD  240
            V +K + QW L+IT YAE LL DL  ++  WPE +  MQRNWIGKSTGA++ F + + D 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD--WPESIKDMQRNWIGKSTGANVTFKVKDTDK  241

Query  241  SITVFTTRPDTIFGATFMSIAPEHPLVEELIDGKPQADDVRAFVERIRNMDRIDRQSDTL  300
             +TVFTTRPDT+FGAT+  +APEH+LV+  I    QA+ V  +  +      + R   + 
Sbjct  242  DFTVFTTRPDTLFGATYAVLAPEHALVDA-ITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  301  EKEGVFTGAYCVNPFTGRKMPIWVANFVLAEYGTGAVMAVPAHDQRDFEFARKYDLPMQV  360
            EK GV TG+Y +NP  G+ MP+W+A++VLA YGTGA+MAVPAHD+RD EFA++++L +  
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  361  VIQPQGEALDPATMSAAWTEAGALVNSGAFDGLANEDAKQRIADDLETTGNGRRTINYRL  420
            V+  +G  ++ A+     TE G  +NS+ +DGL +  A  ++ + LE+ G G   + YRL
Sbjct  361  VL--EGGNVEEAAF----TEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRL  414

Query  421  RDWNISRQRYWGAPIPVIYCDACGVVPEKEENLPVVLPL--DVKTHDDGRSPLPHTPAFY  478
            RDW +SRQRYWG PIP+I  +     +  E +LP+VLP+  D++  + G SPL++     
Sbjct  415  RDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWL  474

Query  479  ECTCPVCGGKARRETDTMDTFVESSWYFARYTDATNDKAPFTPDALRYWLPVDQYIGGVE  538
            E T    G K+RRET+TM     SSWY+ RY D+ N       + L+ WLPVD Y+GG E
Sbjct  475  EVTRE-DGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAE  533

Query  539  HAILHLLYSRFFTKALRDCGFIELDEPFANLLTQGMVL----------------------  576
            HA+LHLLY+RF  K L D G +   EPF +L+ QGM+L                      
Sbjct  534  HAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDG  593

Query  577  ------------MDGSKMSKSKGNVVDPTEMIARYGADTVRLFCLFAAPPERDFDWSESG  624
                           +KMSKS  NVV+P +++ +YGADT+R++ +F +P +  + WSE G
Sbjct  594  SFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEG  653

Query  625  IEGSYRFVGRVWRLVEELREHLLAVGACSSTAEDAKTPVARELRLKEHATVRKAGDDLND  684
            +EGS +F++RV RL+           +    +E+   ++ +      + TV+   +++ D
Sbjct  654  LEGSRKFLDRVYRLI-----------TTKEITEENSGALDKVY----NETVKAVTEQV-D  697

Query  685  RFQFNTAIAAVMELVNALYLAKDELVADESGRKvlssavstvltllsPFTPHLSEELW-A  743
            + +FNTAIA +M +VNA    K++ +  + ++          + L++PF+PHL+EELW A
Sbjct  698  QMKFNTAIAQLMVFVNA--ANKEDKLFSDYAK--------GFVQLIAPFAPHLGEELWQA  747

Query  744  LLGHTESVSTLPWPRWKEDALVRDTVTLVVQVNGKLRGKLDIPADASREEVETLALNEPN  803
            L +  ES+S +PWP   E  LV + V +VVQ++GK+++KL ++ D SREE++ +AL + +
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  804  VLRYLEGVTVRKVVVIPGKLVNVVV  828
            V   + G  + KV+ +P KLVN+V+
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVI  832

930) Deval_1104 in NC_017310


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  555 bits (2096),  Expect = 4e-159, Method: Compositional matrix adjust.
 Identities = 363/865 (42%), Positives = 538/865 (63%), Gaps = 75/865 (8%)

Query  3    YDHQSIETRWQKKWEDSGIFQCDTEADKPKYYVLEMFPYPSG-NIHMGHVRNYSIGDVVA  61
            YDH +IE +WQ  W D+  F+ +T+A KPK+Y L+MFPYPSG  +H+GH   Y+  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  62   RFKRMQGFNVLHPMGWDAFGLPAENAAIKNGTHPAKWTFANIDNMRSQLKRLGYSYDWQR  121
            RFKR QG NVLHPMGWDAFGLPAE+ A+  G +PA  T  NI N + Q++ LG+SYDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  122  EVATCTPEYYRWEQLFFLRFLEKGLVYRKKAAQNWCPKCHTVLANEQVI-EGLCWRCDSA  180
            EV T  P+YY+W Q +F ++ EKGL Y    + NW     T +ANE+V+ +G   R + +
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  181  VEQKELTQWFLRITDYAEELLADLSKLENGWPERVLSMQRNWIGKSTGAEIRFALDGRDD  240
            V +K + QW L+IT YAE LL DL  ++  WPE +  MQRNWIGKSTGA++ F + + D 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD--WPESIKDMQRNWIGKSTGANVTFKVKDTDK  241

Query  241  SITVFTTRPDTIFGATFMSIAPEHPLVEELIDGKPQADDVRAFVERIRNMDRIDRQSDTL  300
             +TVFTTRPDT+FGAT+  +APEH+LV+  I    QA+ V  +  +      + R   + 
Sbjct  242  DFTVFTTRPDTLFGATYAVLAPEHALVDA-ITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  301  EKEGVFTGAYCVNPFTGRKMPIWVANFVLAEYGTGAVMAVPAHDQRDFEFARKYDLPMQV  360
            EK GV TG+Y +NP  G+ MP+W+A++VLA YGTGA+MAVPAHD+RD EFA++++L +  
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  361  VIQPQGEALDPATMSAAWTEAGALVNSGAFDGLANEDAKQRIADDLETTGNGRRTINYRL  420
            V+  +G  ++ A+     TE G  +NS+ +DGL +  A  ++ + LE+ G G   + YRL
Sbjct  361  VL--EGGNVEEAAF----TEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRL  414

Query  421  RDWNISRQRYWGAPIPVIYCDACGVVPEKEENLPVVLPL--DVKTHDDGRSPLPHTPAFY  478
            RDW +SRQRYWG PIP+I  +     +  E +LP+VLP+  D++  + G SPL++     
Sbjct  415  RDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWL  474

Query  479  ECTCPVCGGKARRETDTMDTFVESSWYFARYTDATNDKAPFTPDALRYWLPVDQYIGGVE  538
            E T    G K+RRET+TM     SSWY+ RY D+ N       + L+ WLPVD Y+GG E
Sbjct  475  EVTRE-DGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAE  533

Query  539  HAILHLLYSRFFTKALRDCGFIELDEPFANLLTQGMVL----------------------  576
            HA+LHLLY+RF  K L D G +   EPF +L+ QGM+L                      
Sbjct  534  HAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDG  593

Query  577  ------------MDGSKMSKSKGNVVDPTEMIARYGADTVRLFCLFAAPPERDFDWSESG  624
                           +KMSKS  NVV+P +++ +YGADT+R++ +F +P +  + WSE G
Sbjct  594  SFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEG  653

Query  625  IEGSYRFVGRVWRLVEELREHLLAVGACSSTAEDAKTPVARELRLKEHATVRKAGDDLND  684
            +EGS +F++RV RL+           +    +E+   ++ +      + TV+   +++ D
Sbjct  654  LEGSRKFLDRVYRLI-----------TTKEITEENSGALDKVY----NETVKAVTEQV-D  697

Query  685  RFQFNTAIAAVMELVNALYLAKDELVADESGRKvlssavstvltllsPFTPHLSEELW-A  743
            + +FNTAIA +M +VNA    K++ +  + ++          + L++PF+PHL+EELW A
Sbjct  698  QMKFNTAIAQLMVFVNA--ANKEDKLFSDYAK--------GFVQLIAPFAPHLGEELWQA  747

Query  744  LLGHTESVSTLPWPRWKEDALVRDTVTLVVQVNGKLRGKLDIPADASREEVETLALNEPN  803
            L +  ES+S +PWP   E  LV + V +VVQ++GK+++KL ++ D SREE++ +AL + +
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  804  VLRYLEGVTVRKVVVIPGKLVNVVV  828
            V   + G  + KV+ +P KLVN+V+
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVI  832

931) leuS in NC_017535


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  555 bits (2095),  Expect = 4e-159, Method: Compositional matrix adjust.
 Identities = 352/853 (42%), Positives = 536/853 (63%), Gaps = 60/853 (7%)

Query  11   YDAVAAQEKWSKYWEEHRTFASLDDGSRERRYVLDMFAYPSG-DLHMGHAEAFAIGDVLA  69
            YD  A + KW  +W +++TF +  D+S+ + Y LDMF+YPSG +LH+GH+E+++  D+L+
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  70   RYWRLRGFDVLHPVGWDSFGLPAENAAIKHGTHPAEWTYRNIDTQAASFKRYAVSFDWSM  129
            R+ R +G +VLHP+GWD+FGLPAE+ A+  G +PAE T  NI      ++  + S+DW  
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  130  RLHTSDEEYYRWTQWLFNRFFEKGLAYRKDSWANWCPIDQTVLANEQV-KDGCCERCGAV  188
             ++T+D +YY+WTQW+F +++EKGLAY  +   NW     T +ANE+V  DG  ER G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  189  VTKRQLNQWYFRITDYAQRLLDDMDQIEGKWPERVLSMQRNWIGRSEGAYVDFTIDGHKE  248
            V ++ + QW ++IT YA+RLL+D+++++  WPE +  MQRNWIG+S GA V F + +   
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD--WPESIKDMQRNWIGKSTGANVTFKVKDTDK  241

Query  249  PVRVFTTRPDTLYGATFMVVAPDSALAQEIVSDEARPAFETYLDEVKKKSEIERQATDHE  308
               VFTTRPDTL+GAT+ V+AP+ AL + I + +   A   Y  +   KS++ R     E
Sbjct  242  DFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKE  301

Query  309  KTGVPLGVEATNPVNGAKVPVWAGDYVLADYGTGAVMAVPAHDQRDLDFARTYGIDVIPV  368
            KTGV  G  A NPVNG  +PVW +DYVLA YGTGA+MAVPAHD+RD +FA+ + +D+IPV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  369  IDTGEADPRESGVATTGDGVYQNSGFLNGIATKAEAIAKMCEFLDEKGIGEPTITYRLRD  428
            ++ G+ +      A T DG+  NS+FL+G+  KA AIAKM E L+  G+G+  +TYRLRD
Sbjct  362  LEGGNVE----EAAFTEDGLHINSDFLDGLD-KASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  429  WLLSRQRFWGCPIPIIHCESCGDVPVPDEQLPVKLPDLRGAELAPKGTSPLAGEEASEWR  488
            WL+SRQR+WG PIPIIH E     +VP+ +LP+ LP  ++   +  G SPLA  + ++W 
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLA--NVTDWL  474

Query  489  SVACPSCGGAAQRDTDTMDTFVDSSWYFMRYCCPHYDKGPFDVEAVRRWMPVAQYIGGVE  548
             V+    G  ++R+T+TM    +SSWY++RY  PH      D E +++W+PV  Y+GG E
Sbjct  475  EVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAE  533

Query  549  HATMHLLYSRFFTKVLYDLGMVDFTEPFQRLMNQGQVIN----EGRA-------------  591
            HA +HLLY+RF  KVLYDLG+V   EPFQ+L NQG ++     ++R+             
Sbjct  534  HAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDG  593

Query  592  -----------------MSKSLGNGVDLGKQIDEFGVDAVRTTVIFAGPPDEDIDWADVS  634
                             MSKSL N V+ +  ++++G D++R   +F GP D  I W++ +
Sbjct  594  SFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEG  653

Query  635  PASTLKFLQRAWRVAAEVTSDPDADLTQGDSALRRVTHRSIADITELLEGGRYNVVVARI  694
              ++ KFL+R  R+   +T+   ++  +  +AL +V + ++  +TE ++  ++N  +A++
Sbjct  654  LEGSRKFLDRVYRL---ITTKEITE--ENSGALDKVYNETVKAVTEQVDQMKFNTAIAQL  708

Query  695  MELVNATRKAIDSGCGPADPAVREAVTFTAQALSLVAPYLAEEMWEML-GLEPSVANSHW  753
            M +VNA+ K      + A   V+    F        AP L+EE+W+ L +   S++   W
Sbjct  709  MVFVNAANKEDKLFSDYAKGFVQLIAPF--------APHLGEELWQALTASGESISYVPW  760

Query  754  PTADEKLLVADKVTMVVQVTGKVRAKLTVSPDITEAEAREVALADVNVQRFTEGKEIVKI  813
            P+ DE  LV + V +VVQ+ GKV+AKL V+ D++  E +EVALA+ +VQ    GK+I+K+
Sbjct  761  PSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKV  820

Query  814  IAKLPKMISIVAK  826
            IA   K+++IV K
Sbjct  821  IAVPNKLVNIVIK  833

932) leuS in NC_012918


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  555 bits (2095),  Expect = 5e-159, Method: Compositional matrix adjust.
 Identities = 366/858 (43%), Positives = 550/858 (65%), Gaps = 68/858 (7%)

Query  5    YNPSAVEEKWQGYWAEHESFKATEDPTRKKYYLLEMFPYPSGK-IHMGHVRNYSIGDVIA  63
            Y+ +A+E KWQ++WA++++FK+  D+++ K+Y L+MFPYPSG  +H+GH   Y+  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RFKRMQGYNVLHPMGWDAFGMPAENAAIQHKSHPAKWTYENIAYMRGQLKTLGLSYDWDR  123
            RFKR QG NVLHPMGWDAFG+PAE+ A++  ++PA  T ENIA  + Q+++LG+SYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCDLDYYKWEQRIFLEMYKKGLAYKKSSAVNWCPKCETVLANEQV-EDGCCWRCDSP  182
            E+ T D +YYKW Q+IF  +Y KGLAY    +VNW     T +ANE+V  DG   R + P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VRQKELEQWSFRITNYAQELLDDTYKLTGWPERVLTMQRNWIGRSTGCEIDFPLENGLGK  242
            V +K + QW ++IT YA+ LL+D     +WPE +  MQRNWIG+STG ++ F + +    
Sbjct  184  VVRKPMRQWMLKITAYAERLLED-LEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  IKVFTTRQDTLFGATFMSLAAEHPMALDLAGDAQRAQVEAFIDKVKKTDRIKRGAEDLEK  302
            + VFTTR DTLFGAT+  LA+EH++   ++   Q   V  +  +      + R     EK
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEK  302

Query  303  EGVFTGSYCVNPVTNTKMPIYLANFVLMDYGTGAVMAVPTHDQRDFEFAKKYNLPLKVVI  362
             GV TGSY +NPV    MP+ +A++VL  YGTGA+MAVP+HD+RD EFAK++NL +  V+
Sbjct  303  TGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL  362

Query  363  QPEGETLDPAAMTEAYTAEGIMANSGRFDGMGNGDAKEAIADFLEKEGIGKKTVNFRLRD  422
              EG  ++ A    A+T +G+  NS+ +DG++++ A   + + LE EG+G+  V +RLRD
Sbjct  363  --EGGNVEEA----AFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  423  WGISRQRYWGNPIPVINCDLCGVVAVPEADLPVVLPMDAEF--TGEGGNPLARVDSFTTC  480
            W +SRQRYWG+PIP+I+ +     AVPE++LP+VLP+  ++  +G G +PLA V      
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  481  TCPQCGEAARRETDTMDTFVQSSWYFLRYCSPKFSAGPLDREKVEAWMPVDQYIGGIEHA  540
            T  + G  +RRET+TM     SSWY+LRY  P  +    D E +  W+PVD Y+GG EHA
Sbjct  477  TRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  541  VLHLLYARFFTKVLRDLGYCNVDEPFSNLLTQGMVI-------------------KDG--  579
            VLHLLYARF  KVL DLG     EPF +L+ QGM++                   +DG  
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSF  595

Query  580  -------------AKMSKSKGNVVDPNALIERYGADTARLFSLFAAPPEKDLDWSDQGVD  626
                         AKMSKS  NVV+P+ ++E+YGADT R++ +F +P +  + WS++G++
Sbjct  596  FHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLE  655

Query  627  GSYRFLNRVWRLVYDVLPVIGEAGAVNPDSLGAEAKKLRRAVHKTIKKVSEDVEERFHFN  686
            GS +FL+RV RL+         +  +  ++ GA    L +  + T+K V+E+V++   FN
Sbjct  656  GSRKFLDRVYRLI--------TTKEITEENSGA----LDKVYNETVKAVTEQVDQ-MKFN  702

Query  687  TAIAAVMELVNAIQAFAAKDAPENvavvreavesvvrllAPFVPHFAEELWSQL-GHDTV  745
            TAIA +M +VNA        A  +  +  +   + V+L+APF PH++EELW  L + +  
Sbjct  703  TAIAQLMVFVNA--------ANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGES  754

Query  746  LEAAGWPGYdaaavvdeevtvvIQVNGKLRSKLTVAPDAKEEEVRAQALADDKIKPYLEG  805
            +    WP+YD + +V+++V +V+Q++GK+++KL VA D   EE++  ALA++K+++ + G
Sbjct  755  ISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAG  814

Query  806  KDVKKVVYVPGKLVSIVV  823
            KD+ KV+ VP KLV+IV+
Sbjct  815  KDIIKVIAVPNKLVNIVI  832

933) leuS in NC_015635


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  555 bits (2095),  Expect = 5e-159, Method: Compositional matrix adjust.
 Identities = 353/851 (42%), Positives = 527/851 (62%), Gaps = 62/851 (7%)

Query  16   YDPVAAQQRWQEYWAAEQTFVPADDGSRERRYVLDMFPYPSG-DLHMGHAEAFVMGDIVA  74
            YD  A + +WQ +WA ++TF  + D+S+ + Y LDMFPYPSG +LH+GH+E++   DI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  75   RHLKLRGYDVLHPIGWDSFGLPAENAAIKNDTHPAEWTDRNIETQATSFKRYGLSFDWSR  134
            R  + +G +VLHP+GWD+FGLPAE+ A+  + +PAE T  NI      ++  G+S+DW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  135  RLHTSDPEYYRWTQWLFLRFRERGLAYRKGSYVNWCPVDQTVLANEQVV-NGACERCGAT  193
             ++T+DP+YY+WTQW+F ++ E+GLAY     VNW     T +ANE+V+ +G+ ER G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  194  VTKRQLTQWYFKTTEYAQRLLDDMADLEGGWPERVLAMQRNWIGRSEGAYVDFEIDGVDE  253
            V ++ + QW +K T YA+RLL+D+ +++  WPE +  MQRNWIG+S GA V F + + D 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD--WPESIKDMQRNWIGKSTGANVTFKVKDTDK  241

Query  254  PVTVFTTRPDTLYGATFFVVAPEGELASAIVADGQRAEFEAYLERVKLETEIERQSTDRP  313
              TVFTTRPDTL+GAT+ V+APE  L  AI + +Q      Y  +  L +++ R    + 
Sbjct  242  DFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKE  301

Query  314  KTGVFLGVYATNPVNNERIPVYAADYVLADYGTGAVMAVPAHDQRDLDFARTYDLPVVEV  373
            KTGV  G YA NPVN   +PV  ADYVLA YGTGA+MAVPAHD+RD +FA+ ++L ++ V
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  374  VSTGEPDPADSGIATPGDGTYINSGPLDGLTDKATGVSTIIGQLEEAGVGKGAVTYRLRD  433
            +  G+ + A    A   DG  INS+ LDGL DKA++++ ++  LE  GVG+  VTYRLRD
Sbjct  362  LEGGNVEEA----AFTEDGLHINSDFLDGL-DKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  434  WLLSRQRYWGAPIPIVHCVSCGEVAVPDDQLPVELPPLTGAALAPKGISPLASATEWVNV  493
            WL+SRQRYWG PIPI+H       AVP+ +LP+ LP   +   +  G SPLA+ T+W++V
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  494  DCPSCGGPATRDTDTMDTFVDSSWYFFRYCSPGDVEGPFDPEDVRRWMPVAQYVGGVEHA  553
                 G  + R+T+TM    +SSWY++RY  P + E   D E +++W+PV  YVGG EHA
Sbjct  477  -TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  554  ILHLLYMRFFTKVLHDMGMVDFDEPMRRLLNQGQVINQG---------------------  592
            +LHLLY RF  KVL D+G+V   EP ++L+NQG ++  +                     
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSF  595

Query  593  -------------KSMSKSLGNGVDLGEQIDLYGVDAVRLTVVFAGPPEDDIDWADVSPG  639
                           MSKSL N V+ ++ ++ YG D++R+  +F GP +  I W++ +  
Sbjct  596  FHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLE  655

Query  640  GSAKFLQRAYRL--ASEVTSLPGVDFAGGDAALRSTTHKLLTEIDDCLAGQRFNVMVARV  697
            GS KFL+R YRL  + E+T           +AL    +  +  + + +   +FN  +A++
Sbjct  656  GSRKFLDRVYRLITTKEIT-------EENSGALDKVYNETVKAVTEQVDQMKFNTAIAQL  708

Query  698  MELVNAARKVVDTGAGPADPAVREAAEVVTIVLSLVAPYIAEEMWEAL-GHAPSVADASW  756
            M +VNAA K         D    + A     +++  AP ++EE+W+AL + + S++  +W
Sbjct  709  MVFVNAANK--------EDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPW  760

Query  757  PIVDPSLLITEAVTCVVQVQGKVRARLEVSPDISDGELKELALSADGVVRSLAGRDIAKV  816
            P  D S L+ + V  VVQ++GKV+A+L V+ D+S  EL+E+AL+ + V   +AG+DI KV
Sbjct  761  PSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKV  820

Query  817  IIRAPKLVSIV  827
            I  + KLV+IV
Sbjct  821  IAVPNKLVNIV  831

934) leuS in NC_006085


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  555 bits (2094),  Expect = 5e-159, Method: Compositional matrix adjust.
 Identities = 351/853 (42%), Positives = 536/853 (63%), Gaps = 60/853 (7%)

Query  11   YDAVAAQEKWSKYWEEHRTFASLDDGSRERRYVLDMFAYPSG-DLHMGHAEAFAIGDVLA  69
            YD  A + KW  +W +++TF +  D+S+ + Y LDMF+YPSG +LH+GH+E+++  D+L+
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  70   RYWRLRGFDVLHPVGWDSFGLPAENAAIKHGTHPAEWTYRNIDTQAASFKRYAVSFDWSM  129
            R+ R +G +VLHP+GWD+FGLPAE+ A+  G +PAE T  NI      ++  + S+DW  
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  130  RLHTSDEEYYRWTQWLFNRFFEKGLAYRKDSWANWCPIDQTVLANEQV-KDGCCERCGAV  188
             ++T+D +YY+WTQW+F +++EKGLAY  +   NW     T +ANE+V  DG  ER G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  189  VTKRQLNQWYFRITDYAQRLLDDMDQIEGKWPERVLSMQRNWIGRSEGAYVDFTIDGHKE  248
            V ++ + QW ++IT YA+RLL+D+++++  WPE +  MQRNWIG+S GA V F + +   
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD--WPESIKDMQRNWIGKSTGANVTFKVKDTDK  241

Query  249  PVRVFTTRPDTLYGATFMVVAPDSALAQEIVSDEARPAFETYLDEVKKKSEIERQATDHE  308
               VFTTRPDTL+GAT+ V+AP+ AL + I + +   A   Y  +   KS++ R     E
Sbjct  242  DFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKE  301

Query  309  KTGVPLGVEATNPVNGAKVPVWAGDYVLADYGTGAVMAVPAHDQRDLDFARTYGIDVIPV  368
            KTGV  G  A NPVNG  +PVW +DYVLA YGTGA+MAVPAHD+RD +FA+ + +D+IPV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  369  IDTGEADPRESGVATTGDGVYQNSGFLNGIATKAEAIAKMCEFLDEKGIGEPTITYRLRD  428
            ++ G+ +      A T DG+  NS+FL+G+  KA AIAKM E L+  G+G+  +TYRLRD
Sbjct  362  LEGGNVE----EAAFTEDGLHINSDFLDGLD-KASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  429  WLLSRQRFWGCPIPIIHCESCGDVPVPDEQLPVKLPDLRGAELAPKGTSPLAGEEASEWR  488
            WL+SRQR+WG PIPIIH E     +VP+ +LP+ LP  ++   +  G SPLA  + ++W 
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLA--NVTDWL  474

Query  489  SVACPSCGGAAQRDTDTMDTFVDSSWYFMRYCCPHYDKGPFDVEAVRRWMPVAQYIGGVE  548
             V+    G  ++R+T+TM    +SSWY++RY  PH      D E +++W+PV  Y+GG E
Sbjct  475  EVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAE  533

Query  549  HATMHLLYSRFFTKVLYDLGMVDFTEPFQRLMNQGQVIN----EGRA-------------  591
            HA +HLLY+RF  KVLYDLG+V   EPFQ+L NQG ++     ++R+             
Sbjct  534  HAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDG  593

Query  592  -----------------MSKSLGNGVDLGKQIDEFGVDAVRTTVIFAGPPDEDIDWADVS  634
                             MSKSL N V+ +  ++++G D++R   +F GP D  I W++ +
Sbjct  594  SFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEG  653

Query  635  PASTLKFLQRAWRVAAEVTSDPDADLTQGDSTLRRVTHRSIADITELLEGGRYNVVVARI  694
              ++ KFL+R  R+   +T+   ++  +  ++L +V + ++  +TE ++  ++N  +A++
Sbjct  654  LEGSRKFLDRVYRL---ITTKEITE--ENSGALDKVYNETVKAVTEQVDQMKFNTAIAQL  708

Query  695  MELVNATRKAIDSGCGPADPAVREAVTFTAQALSLVAPYLAEEMWEML-GLEPSVANSHW  753
            M +VNA+ K      + A   V+    F        AP L+EE+W+ L +   S++   W
Sbjct  709  MVFVNAANKEDKLFSDYAKGFVQLIAPF--------APHLGEELWQALTASGESISYVPW  760

Query  754  PTADEKLLVADKVTMVVQVTGKVRAKLTVSPDITEAEAREVALADVNVQRFTEGKEIVKI  813
            P+ DE  LV + V +VVQ+ GKV+AKL V+ D++  E +EVALA+ +VQ    GK+I+K+
Sbjct  761  PSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKV  820

Query  814  IAKLPKMISIVAK  826
            IA   K+++IV K
Sbjct  821  IAVPNKLVNIVIK  833

935) leuS in NC_015673


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  555 bits (2094),  Expect = 6e-159, Method: Compositional matrix adjust.
 Identities = 363/756 (49%), Positives = 509/756 (68%), Gaps = 72/756 (9%)

Query  252   LVYRSNSIVNWCPGLGTVLANEEVTADGRSERGNFPVFRKNLQQWMMRITAYSDRLIDDL  311
             L Y ++  VNW   LGT +ANEEV +DG SERG +PV RK ++QWM++ITAY++RL++DL
Sbjct  148   LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  312   EQLDWPEKVKAMQRNWIGRSRGAEVAFISDATQATSGNSAEIKVFTTRPDTLFGATYMVL  371
             E++DWPE +K MQRNWIG+S GA+V+F    T+       ++ VFTTRPDTLFGATY VL
Sbjct  208   EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDK------DFTVFTTRPDTLFGATYAVL  261

Query  372   APEHELVDQFVEaaaaahggdsagaYEGVDERWTYGQNSPAAAVEAYRDAIAAKSDLERQ  431
             APEH LVD +                           +  A AV  Y+   + KSDL R 
Sbjct  262   APEHALVDAITT-------------------------SDQAEAVADYKRQASLKSDLART  296

Query  432   E-NKEKTGVFLGVHATNPVNGKPVPVFIADYVLTGYGTGAIMAVPGHDERDYEFAQTFGL  490
             +  KEKTGV  G  A NPVNGK +PV IADYVL++YGTGAIMAVP+HDERD EFA+ F L
Sbjct  297   DLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNL  356

Query  491   PIVEVLQGGNLEVEAFTEDGPHVNSANESGLDLNGLAKEEAIAKAIQWLEGRGVGEEKIQ  550
              I+ VL+GGN+E  AFTEDG H+NS       L+GL K  AIAK ++WLE+ GVG+E++ 
Sbjct  357   DIIPVLEGGNVEEAAFTEDGLHINSDF-----LDGLDKASAIAKMVEWLEAEGVGNENVT  411

Query  551   YKLRDWLFARQRYWGEPFPIVYDEDGVAHPLPESMLPVLLPEVEDYKPVSFDPEDKNTEP  610
             Y+LRDWLF+RQRYWGEP+PI+  EDG + ++PES LP++LP   D +P        +   
Sbjct  412   YRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTG  463

Query  611   QPPLAKAKEWVEVKLDLGDGEKTYWRDTNVMPQWAGSSFYQLRYIDPKNENALVDIENER  670
             ++PLA+  +W+EV  + G   +   R+TN MPQWAGSS Y LRYIDP N + L D E  +
Sbjct  464   ESPLANVTDWLEVTREDGVKGR---RETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLK  520

Query  671   YWVGPREGRPAGGVDLYVGGVEHAVLHLLYSRFWHKVLFDLGHVSSFEPYHRLYNQGYIQ  730
              W+          VD+YVGG EHAVLHLLY+RFWHKVL+DLG V++ EP+++L+NQG I 
Sbjct  521   QWL---------PVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMIL  571

Query  731   AYAYTDSRGVYVPAENVEERDGKFFYKPADGGEEIEVKQEYGKMGKSLKNSVSPDEICDN  790
             + +Y DSRG  V++++VE RDG FF    + GEE+E  Q  +KM+KSLKN V+PD++ ++
Sbjct  572   GTSYRDSRGALVATDKVEKRDGSFF--HVETGEELE--QAPAKMSKSLKNVVNPDDVVEQ  627

Query  791   YGADTLRVYEMSMGPLDTSRPWATKDVVGAQRFLQRAWRLVVNEHTGELNVSDADLSDDD  850
             YGADTLRVYEM MGPLD+S +W+  ++ G+++FL+R  RL+   +  E N +  D     
Sbjct  628   YGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALD-----  682

Query  851   NRALHRAIAGIHEDYTELRDNTAVAKLIEYVNYLTKAYAGDAQAPREAVEPLVQMISPVA  910
              +  + ++ ++ E+  +++ NTA+A+L+ +VN   K    + +   +    +VQ+I+P A
Sbjct  683   -KVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANK----EDKLFSDYAKGFVQLIAPFA  737

Query  911   PHIAEEMWVKLGHEG-GLTYVPFPSWDEKWLVDDTIELPVQVMGKLRGRITVQADASRED  969
             PH++EE+W  L   G +++YVP PS DE  LV++ +E+ VQ+ GK+++++ V  D SRE+
Sbjct  738   PHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREE  797

Query  970   IEKAALEEPNVVGHIAGKSIAKIIVVPGKMVNIVAK  1005
             ++  AL + +V ++IAGK I K+I VP K+VNIV K
Sbjct  798   LQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833


 Score =  134 bits (493),  Expect = 2e-32, Method: Compositional matrix adjust.
 Identities = 76/151 (51%), Positives = 102/151 (68%), Gaps = 11/151 (7%)

Query  52   AQIEQRWQNYWADQGTFHTPNPVGALASDSGKDLPQDRKFIQDMFPYPSGVGLHVGHPLG  111
            + IE +WQ +WAD+ TF T           G D ++ + +  DMFPYPSG GLHVGHP G
Sbjct  7    TAIEPKWQAFWADNHTFKT-----------GTDASKPKFYALDMFPYPSGAGLHVGHPEG  55

Query  112  YIATDVYARFQRMNGANVLHTLGYDAFGLPAEQYAVQTGTHPRTTTMANIENMERQLGRL  171
            Y ATD+ +RF+R +G NVLH +G DAFGLPAEQYA++TG +P   T  NI N  RQ+  L
Sbjct  56   YTATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINAL  115

Query  172  GLGHDKRRAIATTDEDFYRWTQWIFLQIYNS  202
            G++ D  R + TTD ++Y+WTQWIF ++Y+ 
Sbjct  116  GFSYDWDREVNTTDPNYYKWTQWIFTKLYEK  146

936) leuS in NC_021290


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  555 bits (2094),  Expect = 6e-159, Method: Compositional matrix adjust.
 Identities = 361/866 (42%), Positives = 563/866 (66%), Gaps = 47/866 (5%)

Query  5    YVPQSIEPAVQKHWDAKKTFKAVEKVDKEKFYCLSMFPYPSGR-LHMGHVRNYTIGDVIS  63
            Y   +IEP  Q  W  + TFK+     K KFY L MFPYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRLNGKNVLQPIGWDAFGLPAENAAIKNNTAPAPWTYENIEYMKNQLKMLGLGYDWDR  123
            R++R +G NVL+P+GWDAFGLPAE+ A+     PA  T ENI   K Q++ LG++YDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCKPDYYRWEQWFFTKLYEKGLVYKKTSSVNWCPNDMTVLANEQVV-DNCCWRCDTP  182
            E+ T  P+YY+W QW+FTKLYEKGL Y    +VNW  +  T +ANE+V+ D    R + P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VEQKEIPQWFIKITDYAEELLNDIDNLEGWPEMVKTMQRNWIGRSEGVNISFAIEGQAEH  242
            V +K + QW +KIT YAE LL+D+++++ WPE +K MQRNWIG+S G N++F + +   +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LEVYTTRPDTFMGVTYVGIAAGHPL--ALQAAQTNPALAAFI-EECKNTKVAEAELATME  299
            + V+TTRPDT+ G TY  +A+ H+L  A+ +++   A+A +  +   ++ +A ++LA  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGMATGLYAIHPLDGRKVPVWVANFVLMNYGTGAVMAVPGHDLRDHEFATKYGLEIKPV  359
            K G+ TG YAI+P++G+ +PVW+A++VL +YGTGA+MAVP+HD RD EFA ++ L+I PV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  360  IKPVDGELPNVIDAAYTDKGVLFNSGEFDGLEFQPAFDAIASKLESLGCGKRTVNFRLRD  419
            +        NV +AA+T+ G+ +NS+ +DGL+  +A+  +   LE+ G G+  V +RLRD
Sbjct  362  LEG-----GNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMLTLADGTVVPTPEDQLPVLLP--EDVVMDGI-QSPIKADAEWAKT  476
            W  SRQRYWG PIP++   DGT  + PE +LP++LP   D+   G  +SP+   ++W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  TY-NGQEAFRETDTFDTFMESSWYYARYCSPDYDKGMLDPAAANHWLPVDQYIGGIEHAC  535
            T  +G  + RET+T      SSWYY RY  P+    + D    ++WLPVD Y+GG EHA 
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLLYARFFHKLLRDAGLVNSDEPFKRLLCQGMVLADAFYYKDEKGGNVWVSPTDVKVER  595
            +HLLYARF HK+L D G+V + EPF++L+ QGM+L+ +  Y+D +G+ V    +  KVE+
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS--YRDSRGALV----ATDKVEK  590

Query  596  DEKGRITKAVDNEGREVIHSGMTKMSKSKNNGIDPQLMVERYGADTVRLFMMFASPAEMT  655
                R     + E  E ++ + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P + +
Sbjct  591  ----RDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  656  LEWSDSGVEGAQRFLRRLWR-ITFEHVSAGIAPALNVAALSGDQKAVRRELHKTIAKVSD  714
            + WS+ G+EG+++FL R+ R IT  +++   + AL+            +  + T+  V++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALD------------KVYNETVKAVTE  694

Query  715  DVGRRQTFNTAIAAIMELMNNLAKLGSDEQDRALMQEALEAVVVMLYPITPHIGFELWKM  774
            +V++ + FNTAIA +M ++N      + +++  L  +   + V ++ P++PH+G ELW+ 
Sbjct  695  QVDQMK-FNTAIAQLMVFVN------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  775  L-GKGDDVDHAVWPVADEAAMVETEKLVVVQINGKMRGKLTVPAEISQADVEKLAMADAS  833
            L + G+ +    WP  DE+ +VE +  +VVQI+GK+++KL V+ ++S+ +++ +A+A+  
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  834  VQKFTDGLTVRKVIYVPGKLLNIVAN  859
            VQ    G  + KVI VP KL+NIV +
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVIK  833

937) leuS in NC_015125


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  554 bits (2090),  Expect = 1e-158, Method: Compositional matrix adjust.
 Identities = 381/881 (44%), Positives = 552/881 (63%), Gaps = 88/881 (9%)

Query  14   FDAHAIQEKWQRAWADKDPFRAGGDDDKRPRKYVLAMFPYPSG-DLHMGHAENYLYSDIV  72
            +D  AI+ KWQ  WAD++ F++G D  K P+ Y L MFPYPSG +LH+GH+E Y  +DI+
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASK-PKFYALDMFPYPSGAGLHVGHPEGYTATDIL  62

Query  73   ARFWRHRGYNVLNPIGWDSFGLPAENAAIKRGADPVEWTYANIAQQKASLKDYGVSFDWS  132
            +RF R +G NVL+P+GWD+FGLPAE+ A+  G DP E T  NIA+ K  ++  G S+DW 
Sbjct  63   SRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWD  122

Query  133  RVLHTSDPEYYRWNQWLFQKLYEKGLAYRKDALVNWDPVDQTVLANEQVLPDGTSERSGA  192
            R ++T+DP+YY+W QW+F KLYEKGLAY  +  VNW     T +ANE+VLPDGTSER+G 
Sbjct  123  REVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGY  182

Query  193  VVVKKKLTQWFLRITDYADRLLDDLNQLEGFWPSKVIQMQRNWIGRSVGADITFEIEGRD  252
             VV+K + QW L+IT YA+RLL+DL++++  WP  + +MQRNWIG+S GA++TF + + D
Sbjct  183  PVVRKPMRQWMLKITAYAERLLEDLEEVD--WPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  253  EKITVFSTRPDTLHGATFFVVAPesdlaaelaasadQGVRETFEAYLAQVQRATDIERQA  312
              +TVF+TRPDTL GAT+ V+APE  L   +++S +    E+   Y  Q    +D+ R  
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQA---EAVADYKRQASLKSDLARTD  297

Query  313  TDRPKTGVFLGHYAINPINGEKLPIWAADYVLADYGHGAVMAVPAHDQRDLDFARAFDLP  372
              + KTGV  G YAINP+NG  +P+W ADYVLA YG GA+MAVPAHD+RD +FA+ F+L 
Sbjct  298  LAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLD  357

Query  373  VKVVVDTLAPVTGAIPVIELDDEGVPIDPLGDVEETDPVKTGIALTGDGRMINSGSLNGL  432
            +             IPV+E           G+VEE+       A+T DG  INS+ L+GL
Sbjct  358  I-------------IPVLE----------GGNVEEA-------AFTEDGLHINSDFLDGL  387

Query  433  SKRNAIARVIEELEAKGVGRAAKTYRLRDWLISRQRYWGTPIPMLHGEDGSITPVPADQL  492
             K +AIA+++E LEA GVG    TYRLRDWL+SRQRYWG PIP++H EDG+ T+VP  +L
Sbjct  388  DKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESEL  447

Query  493  PVVLPSVEGLDLKPKGTSPLGAATDWVQVTDPETGQTLLRDPDTMDTFVDSSWYYLRFLS  552
            P+VLP   ++     G SPL+  TDW++VT  E G    R+ +TM    +SSWYYLR++ 
Sbjct  448  PLVLPVTKDIRPSGTGESPLANVTDWLEVT-REDGVKGRRETNTMPQWAGSSWYYLRYID  506

Query  553  PNSETEAFSGREASK-WGPVDFYIGGVEHAILHLLYARFITKALFDMGLVEFTEPFSSLI  611
            P+ +TE +++ E  K W PVD+Y+GG EHA+LHLLYARF  K L+D+G+V   EPF  L+
Sbjct  507  PH-NTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLF  565

Query  612  NQGMVI--------------------------------LD--GAKMSKSKGNLVLFQEEL  637
            NQGM++                                L+   AKMSKS  N+V  ++ +
Sbjct  566  NQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVV  625

Query  638  DAHGADALRVALAFAGPVEDDKDWNDVSTTGAAKFLARALRIAHDVDSETDVVWAEGDQS  697
            +  GAD+LRV   F GP++    W++ +  G+ KFL R  R+     +  ++   E   +
Sbjct  626  EQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLI----TTKEIT-EENSGA  680

Query  698  LRRVTHRLLAEAPNLIEQTKFNVVVARLMELVNATRKAIDGSAGTSDPAVREAAEVIAMT  757
            L +V +  +    + ++Q KFN  +A+LM +VNA+ K         D    + A  +   
Sbjct  681  LDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKE--------DKLFSDYAKGFVQL  732

Query  758  LDLFAPHTAEEMWQTLGYDG-FVGLATWRQADPTLLVEDSVTAVVQIDGKVRGTLEVSAK  816
            +  FAPH +EE+WQ+L   G  ++   W   D + LVE+ V  VVQI GKV++ L V+  
Sbjct  733  IAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKD  792

Query  817  IGADELEKLARSDEKVRRALGDREIVRAVVRPPKVVSFSTK  857
            ++ +EL+ +A ++EKV+  +++++I++ +  P K+V++  K
Sbjct  793  LSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

938) Rahaq2_3238 in NC_016818


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  554 bits (2090),  Expect = 1e-158, Method: Compositional matrix adjust.
 Identities = 364/865 (43%), Positives = 561/865 (65%), Gaps = 46/865 (5%)

Query  5    YRPEDIESHVQLHWQEKQTFKVTEQPGKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIS  63
            Y    IE+  Q  W +++TFK   +++K K+Y L M+PYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYENIEYMKNQLKLLGFGYDWDR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T ENI   K Q++ LGF+YDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVATCKPDYYRWEQWFFTKLYEKGLVYKKTSAVNWCPHDLTVLANEQVI-DGCCWRCDTK  182
            EV T  P+YY+W QW+FTKLYEKGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADQLLNDLDTLESWPEQVKTMQRNWIGRSEGVEITFDVADSDEK  242
            V RK + QW +KITAYA++LL+DL+ ++ WPE +K MQRNWIG+S G ++TF V D+D  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  VTVYTTRPDTFMGATYVAVAAGHPLAQ--LGAQNNPALNDFIDECR-NTKVAEAEMATME  299
             TV+TTRPDT+ GATY  +A+ H+L +    +++  A+ D+  +   ++ +A +++A  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGMATGLFAIHPLSGEKLPVWVANFVLMEYGTGAVMAVPAHDQRDWEFATKYNLQIKPV  359
            K G+ TG +AI+P++G  +PVW+A++VL  YGTGA+MAVPAHD+RDWEFA ++NL+I PV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  360  ILNVDGSQPDVTAEAMTEKGTLYNSGEFDGLNHEDGFNAIADKLVAQGVGQRKVNYRLRD  419
            +   +G+  +V   A TE G   NS+ +DGL+   ++  + + L A+GVG+ +V YRLRD
Sbjct  362  L---EGG--NVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMITLEDGTVIPTPEDQLPVVLP--EDVVMDGIT-SPIKADPEWAKT  476
            W  SRQRYWG PIP+I  EDGT  + PE +LP+VLP   D+   G   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  T-VNGMPGLRETDTFDTFMESSWYYARYTCPQYDEGMLDPAAANYWLPVDQYVGGIEHAI  535
            T  +G+ G RET+T      SSWYY RY  P+  E + D    + WLPVD YVGG EHA+
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLMYFRFFHKLMRDAGLVDSDEPAKRLLCQGMVLADAFYYTGNNGERIWVSPADAIVER  595
            +HL+Y RF HK++ D G+V + EP ++L+ QGM+L+ +  Y ++ G    + ++D +  R
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS--YRDSRGA---LVATDKVEKR  591

Query  596  DEKGRITKATDPQGHELVYAGMSKMSKSKNNGIDPQVMVDKYGADTVRLFMMFASPAEMT  655
            D  G +      +  E    + +KMSKS +N ++P+ +V++YGADT+R++ MF +P + +
Sbjct  592  D--GSFFHVETGEELE---QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  656  LEWQESGVEGANRFLKRVWKLAFEHTEKGQVAALDVASLNEAQKDLRRDLHKTIAKVTDD  715
            + W E G+EG+ +FL RV +L         +++ +++  +E    L +  + T+  VT++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRL---------ITTKEIT--EENSGALDKVYNETVKAVTEQ  695

Query  716  IGRRQTFNTAIAAIMELMNKLGRAPQDTEQDRALLQEALLAVVRMLYPFTPHVCFTLWQS  775
            +++ + FNTAIA +M ++N        ++++  L+ +   + V+++ PF+PH+   LWQ+
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  776  LKGEGD-VDTAPWPQADEQAMVEDSKLVVVQVNGKVRAKITVAADATEQQVRDRAAEEHL  834
            L + G+ +   PWP  DE  +VE+   +VVQ++GKV+AK+ VA D + +++++ A  ++ 
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  835  VAKYLDGVTVRKVIYVPGKLLNLVV  859
            V   + G  + KVI VP KL+N+V+
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVI  832

939) Bmur_2055 in NC_014150


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  554 bits (2090),  Expect = 1e-158, Method: Compositional matrix adjust.
 Identities = 358/867 (42%), Positives = 550/867 (64%), Gaps = 53/867 (6%)

Query  3    YNFTTIEKKWQKFWKDNNSFKTVSKPTDKKYYVLEMFPYPSGK-MHMGHVSNYTIADSIA  61
            Y+ T+IE KWQ FW DN++FKT + ++  K+Y L+MFPYPSG  +H+GH   YT +D ++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  62   RYYRLLGYDILHPMGWDAFGMPAENAAIEHKTHPAEWTLKNIANMKEQLNLLGYSYDWDR  121
            R+ R  G ++LHPMGWDAFG+PAE+ A++   +PAE T  NIAN K Q+N LG+SYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  122  EVTTCLPDYYKWGQWFILKMYEKGLLYRKGGDVNWCDHCNTVLANEQVTPEGTCWRCDGE  181
            EV T  P+YYKW QW++ K+YEKGL Y     VNW ++  T +ANE+V P+GT  R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VTKKKLEQWYIKVTDYAEQLDADLKLLEGYWPDNVIAMQKNWIGRSVGAYVNFTL-DDGK  240
            V +K + QW +K+T YAE+L  DL  ++  WP+++  MQ+NWIG+S GA V F + D +K
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD--WPESIKDMQRNWIGKSTGANVTFKVKDTDK  241

Query  241  DFPIFTTRPDTIYGVTYMAIAWNYDGLLD-MCTAEQKNAVEEFIKKSA-KID-QKTDYEK  297
            DF +FTTRPDT++G TY  +A   ++L+D + T++Q +AV ++ ++++ K D  +TD  K
Sbjct  242  DFTVFTTRPDTLFGATYAVLA-PEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  298  E--GVFTGRYVINPFNKEKAPLYAANFVLAEYGSGAVMAVPAHDQRDFEFAKKYNIPVKV  355
            E  GV TG Y INP N    P+  A++VLA YG+GA+MAVPAHD+RD EFAK++N+ +  
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  356  VIQNADNSLKAENMTEAYTEDGVVVNSDILNGLSTRDAIKKAISYASEKGFGSEKVQYKL  415
            V++ ++          A+TEDG+ +NSD+L+GL    AI K +      G G+E+V Y+L
Sbjct  361  VLEGGNVE------EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRL  414

Query  416  RDWLISRQRYWGNPLPFVHCEKCGIVPVPESELPITLPMDIEF---TVGDNPLKKSESFV  472
            RDWL+SRQRYWG+P+P++H E     +VPESELP+ LP+  ++     G++PL +    +
Sbjct  415  RDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWL  474

Query  473  NTTCPKCGGKAKRETDTMDTFTCSSWYYARYTDAHNDKMPFDPAIANAWLGVDQYIGGIE  532
            + T    G K++RET+TM   + SSWYY RY D+HN     D  + + WL VD Y+GG E
Sbjct  475  EVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAE  533

Query  533  HACMHLLYSRFWYKFMRDIGLIKGDEPFNRLLTQGMVLANSYESRELKKFYTQEEMNNKA  592
            HA +HLLY+RFW K + D+G++   EPF++L+ QGM+L+ SY  R+ +      +  +K 
Sbjct  534  HAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY--RDSRGALVATDKVEK-  590

Query  593  YEKDGI-----KKEDIIVKMEKMSKSKANGIDPTEIIELFGADAVRIFVMFAAPPEKDKE  647
              +DG        E++     KMSKS  N ++P +++E +GAD++R++ MF +P +    
Sbjct  591  --RDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIA  648

Query  648  WSDEGVKGSARFLNRIWNLFLKYKDEEAFKNNKSFDYNNLSKEAKNLYKKYHktikkvti  707
            WS+EG+ GS +FL+R+  L+                 ++++ E      K  +   K   
Sbjct  649  WSEEGLEGSRKFLDRVYRLITT---------------KEITEENSGALDKVYNETVKAVT  693

Query  708  dikdRFHFNTAIAALMELLNDMSSIKLNGDDEYAMFKEVIRGYLILLNPIAPHITEELYQ  767
            +  D+  FNTAIA LM ++N        ++ E  +F +  +G++ L+ P+APH+ EEL Q
Sbjct  694  EQVDQMKFNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  768  ILNFGKMILE-ESWVEHNEEYCKDDVFELVFQVNGKIRDRVEADINISEDDAKTQALSSE  826
             L  +   +   +W   +E    ++  E+V Q++GK++ ++    ++S ++ +  AL++E
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  827  KVKQFTDGKNIVKVVYVKGKLVNIVVK  853
            KV+    GK+I+KV+ V  KLVNIV+K
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVIK  833

940) Vpar_0964 in NC_013520


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  554 bits (2093),  Expect = 6e-159, Method: Compositional matrix adjust.
 Identities = 372/857 (44%), Positives = 548/857 (64%), Gaps = 66/857 (7%)

Query  5    YVAQDIEKKWQQYWEDNHTFKTEYDESKEKYYVLEMFPYPSG-NLHMGHVRNYSIGDVVA  63
            Y    IE KWQ +W DNHTFKT  D SK K+Y L+MFPYPSG  LH+GH   Y+  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RFKKMKGFNVLHPMGWDSFGMPAENAAIKHGIAPKTWTLDNIENMKLQQKALGLSYDWDR  123
            RFK+ +G NVLHPMGWD+FG+PAE+ A+  G  P   T +NI N K Q +ALG+SYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVATCKEDYYKWTQWFFEQFYKKGLAYKKEAKVNWCETCHTVLANEQVI-DGACWRCDNP  182
            EV T   +YYKWTQW+F ++Y KGLAY  E  VNW E   T +ANE+V+ DG+  R + P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VEKKDLSQWFLRITEYAdrlltdldtldHWPQRVKLMQKNWIGRSEGTEFSFEVPSINER  242
            V +K + QW L+IT YA   L +     +WP+ +K MQ+NWIG+S G++ +F V   +  
Sbjct  184  VVRKPMRQWMLKITAYA-ERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  VSVYTTRVDTIYGVSYVVLAPEHPYVERIIENAPNKAELESFITRMRNMSDIDRTSTEAP  302
             +V+TTR DT++G +Y VLAPEH+ V+ I  +    A +  +  +    SD+ RT     
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEA-VADYKRQASLKSDLARTDLAKE  301

Query  303  KEGMFTGSYAVNPMSGEQVPVWIANYVLVDYGTGAVMGSPAHDERDWEFAHKYDLPIKQV  362
            K G+ TGSYA+NP++G ++PVWIA+YVL  YGTGA+M+ PAHDERDWEFA +++L I  V
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  363  VACEGEEYSLEKWQEWYHEDGILVNSGDYNGQTSAEARKNITAALNERGIGEGKVNFRLR  422
            +     E +       + EDG+ +NS+  +G   A A  ++   L+  G+G+ +V +RLR
Sbjct  362  LEGGNVEEAA------FTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  423  DWLISRQRYWGVPIPVVYCEKCGEQLVPEEQLPVRLP--ENVKFESGAVSPLATSESFLN  480
            DWL+SRQRYWG PIP++  E      VPE +LP+ LP   +++  + + SPLA     L+
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  481  TTCPKCGGPARRETDTMDTFIDSSWYFLRYTDAKNDQAPFDKKIANYWMNVDQYIGGIEH  540
             T    G  +RRET+TM    +SSWY+LRY D+ N +   D  + + W+ VD Y+GG EH
Sbjct  476  VTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEH  534

Query  541  AILHLLYSRFFVKVIHDLDLIEANEPFRGLLTQGMVL-------------------KEGS  581
            A+LHLLY+RF  KV+ DL+++ ++EPF+ L+ QGM+L                   ++GS
Sbjct  535  AVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGS  594

Query  582  ---------------KMSKSKGNVVSPEEIINTYGADTARLFILFAAPVDRDLDWSDQGV  626
                           KMSKS  NVV+P+++++ YGADT R++ +F +P+D  + WS++G+
Sbjct  595  FFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGL  654

Query  627  EGSYRFLGRVWRIVDTYNEEAKKNVTGELTKDEFALRRELHRVIKKVTEDLDNNFNFNTA  686
            EGS +FL+RV R++ T      K++T E +    AL +  +  +K VTE++D + +FNTA
Sbjct  655  EGSRKFLDRVYRLITT------KEITEENSG---ALDKVYNETVKAVTEQVD-QMKFNTA  704

Query  687  ISAIMELVNAMYAYKDKAETINSALANELTRSLLLLLAPFVPHITEELWHELGETT-SIH  745
            I+ +M +VN        A   +  L ++ +++++ L+APF PH+ EELW+ L  +  SI 
Sbjct  705  IAQLMVFVN--------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESIS  756

Query  746  TENWPvyeeaalvvdevevvlqvNGKVRDKLTVSVNITKEELETMAKESSRVQEFTEGKN  805
               WP Y+E+ LV ++VE+V+Q++GKV+ KL V+ ++++EEL+ +A  + +VQ    GK+
Sbjct  757  YVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKD  816

Query  806  IVKVIYVPGKLVNIVVK  822
            I+KVI VP KLVNIV+K
Sbjct  817  IIKVIAVPNKLVNIVIK  833

941) leuS in NC_010842


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  554 bits (2093),  Expect = 7e-159, Method: Compositional matrix adjust.
 Identities = 354/698 (51%), Positives = 483/698 (70%), Gaps = 50/698 (7%)

Query  205  LVYEANIPVNWCEALGTVLANEEV---EEWTSKGYSVERKPMRQYMMRITAYAERLLNDL  261
            L YEA++PVNW E LGT +ANEEV         GY+V RKPMRQ M++ITAYAERLL+DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  262  SLCEWPPSTLEMQRNWIGKSEGLELSFHVPSLNKDITVYTTRPDTIFGATYLVLAPEHAL  321
               +WP S  +MQRNWIGKS G +++F V   +KD+TV+TTRPDT+FGATY VLAPEHAL
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  322  VAELTTPEQTEAVGQYQKDCSLKSDLERTELNKDKTGVFTGAYAQLPTDPSVKVPIYISD  381
            V  +TT++Q+EAV++Y+++ SLKSDL RT+L K+KTGV TG+YA  P +    +P+ I+D
Sbjct  268  VDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAINPVNGK-EMPVWIAD  326

Query  382  YVLISYGTGAIMAVPAHDQRDYDFAVKFNLPIKQVIDGKMETNLAFDSKDSVCINSSSAE  441
            YVL SYGTGAIMAVPAHD+RD +FA +FNL I  V++G    + AF + D++ INS    
Sbjct  327  YVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEAAF-TEDGLHINSDF--  383

Query  442  VQLDGKSYKDAFQTMVVWAEKKGIGRKKIQFKLRDWLFARQRYWGEPIPLVHFEDGSPKA  501
              LDG     A+  MV W E  G+G  ++ ++LRDWLF+RQRYWGEPIP++H EDG++ A
Sbjct  384  --LDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTA  441

Query  502  LSDSELPLVLPDLEEFKPSGTGESPLALAKDWLVYKDPETGEIGKRETNTMPQWAGSCYY  561
            +++SELPLVLP   +++PSGTGESPLA   DWL     E G  G+RETNTMPQWAGS  Y
Sbjct  442  VPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT-REDGVKGRRETNTMPQWAGSSWY  500

Query  562  YLRYIDPRNNDKLIDPELEKMWMPVEVYVGGAEHAVLHLLYSRFWHKILFDLGHVSTPEP  621
            YLRYIDP+N +KL D EL K W+PV++YVGGAEHAVLHLLY+RFWHK+L+DLG V+T EP
Sbjct  501  YLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEP  560

Query  622  FKKLVHQGLILG---------------------------------EDKGKMSKSRGNVVN  648
            F+KL +QG+ILG                                 +  +KMSKS  NVVN
Sbjct  561  FQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVN  620

Query  649  PDDVVSEFGADTLRLFEMFMGPFEMSKPWSKNGVDGVFRFLNRVWRLFHSGENESFFVED  708
            PDDVV ++GADTLR++EMFMGP++ S +WS +G++G  +FL+RV RL+ + E        
Sbjct  621  PDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITE-----  675

Query  709  IEPNEAEQKTLHRTIKKVKDDIDSFSFNTAVSQMMIFINEFTSNPRKPKQVLEPFVLALS  768
             E + A +K  + T+K V +++D   FNTA++Q+M+F+N    + +   +    FV  ++
Sbjct  676  -ENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIA  734

Query  769  PFAPHLAEELWAKL-GHTDSLAYHPYPKWDEKYLIDANITIVVQVNGKMRGEFLAPREIE  827
            PFAPHL+EELW  L +  +S++Y P P  DE  L++ ++ IVVQ++GK+++ ++ ++++ 
Sbjct  735  PFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLS  794

Query  828  EKEALSLAKEVEKAKPFWVGKEIKKEIYVKGKLVNIVV  865
              E   +A   EK ++   GK+I K I V  KLVNIV+
Sbjct  795  REELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832


 Score =  192 bits (712),  Expect = 1e-49, Method: Compositional matrix adjust.
 Identities = 94/142 (67%), Positives = 122/142 (86%), Gaps = 0/142 (0%)

Query  3    YPFQDIEQKWQKYWDHHQTFRTNTHSSKPKYYCLDMFPYPSGAGLHVGHPEGYTATDIIS  62
            Y    IE KWQ +W +++TF+T T++SKPK+Y LDMFPYPSGAGLHVGHPEGYTATDI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RLKRMEGYEVLHPMGWDAFGLPAERYAMTTGIHPRTTTKNNIDTFRRQIKSLGLSYDWER  122
            R+KR +G +VLHPMGWDAFGLPAE+YAM TG +P   T +NI  F+RQI++LG+SYDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EISTTHPDYYRWTQWIFLQIYN  144
            E++TT+P+YY+WTQWIF ++Y+
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYE  145

942) leuS in NC_010602


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  554 bits (2093),  Expect = 7e-159, Method: Compositional matrix adjust.
 Identities = 354/698 (51%), Positives = 483/698 (70%), Gaps = 50/698 (7%)

Query  205  LVYEANIPVNWCEALGTVLANEEV---EEWTSKGYSVERKPMRQYMMRITAYAERLLNDL  261
            L YEA++PVNW E LGT +ANEEV         GY+V RKPMRQ M++ITAYAERLL+DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  262  SLCEWPPSTLEMQRNWIGKSEGLELSFHVPSLNKDITVYTTRPDTIFGATYLVLAPEHAL  321
               +WP S  +MQRNWIGKS G +++F V   +KD+TV+TTRPDT+FGATY VLAPEHAL
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  322  VAELTTPEQTEAVGQYQKDCSLKSDLERTELNKDKTGVFTGAYAQLPTDPSVKVPIYISD  381
            V  +TT++Q+EAV++Y+++ SLKSDL RT+L K+KTGV TG+YA  P +    +P+ I+D
Sbjct  268  VDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAINPVNGK-EMPVWIAD  326

Query  382  YVLISYGTGAIMAVPAHDQRDYDFAVKFNLPIKQVIDGKMETNLAFDSKDSVCINSSSAE  441
            YVL SYGTGAIMAVPAHD+RD +FA +FNL I  V++G    + AF + D++ INS    
Sbjct  327  YVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEAAF-TEDGLHINSDF--  383

Query  442  VQLDGKSYKDAFQTMVVWAEKKGIGRKKIQFKLRDWLFARQRYWGEPIPLVHFEDGSPKA  501
              LDG     A+  MV W E  G+G  ++ ++LRDWLF+RQRYWGEPIP++H EDG++ A
Sbjct  384  --LDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTA  441

Query  502  LSDSELPLVLPDLEEFKPSGTGESPLALAKDWLVYKDPETGEIGKRETNTMPQWAGSCYY  561
            +++SELPLVLP   +++PSGTGESPLA   DWL     E G  G+RETNTMPQWAGS  Y
Sbjct  442  VPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT-REDGVKGRRETNTMPQWAGSSWY  500

Query  562  YLRYIDPRNNDKLIDPELEKMWMPVEVYVGGAEHAVLHLLYSRFWHKILFDLGHVSTPEP  621
            YLRYIDP+N +KL D EL K W+PV++YVGGAEHAVLHLLY+RFWHK+L+DLG V+T EP
Sbjct  501  YLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEP  560

Query  622  FKKLVHQGLILG---------------------------------EDKGKMSKSRGNVVN  648
            F+KL +QG+ILG                                 +  +KMSKS  NVVN
Sbjct  561  FQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVN  620

Query  649  PDDVVSEFGADTLRLFEMFMGPFEMSKPWSKNGVDGVFRFLNRVWRLFHSGENESFFVED  708
            PDDVV ++GADTLR++EMFMGP++ S +WS +G++G  +FL+RV RL+ + E        
Sbjct  621  PDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITE-----  675

Query  709  IEPNEAEQKTLHRTIKKVKDDIDSFSFNTAVSQMMIFINEFTSNPRKPKQVLEPFVLALS  768
             E + A +K  + T+K V +++D   FNTA++Q+M+F+N    + +   +    FV  ++
Sbjct  676  -ENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIA  734

Query  769  PFAPHLAEELWAKL-GHTDSLAYHPYPKWDEKYLIDANITIVVQVNGKMRGEFLAPREIE  827
            PFAPHL+EELW  L +  +S++Y P P  DE  L++ ++ IVVQ++GK+++ ++ ++++ 
Sbjct  735  PFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLS  794

Query  828  EKEALSLAKEVEKAKPFWVGKEIKKEIYVKGKLVNIVV  865
              E   +A   EK ++   GK+I K I V  KLVNIV+
Sbjct  795  REELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832


 Score =  192 bits (712),  Expect = 1e-49, Method: Compositional matrix adjust.
 Identities = 94/142 (67%), Positives = 122/142 (86%), Gaps = 0/142 (0%)

Query  3    YPFQDIEQKWQKYWDHHQTFRTNTHSSKPKYYCLDMFPYPSGAGLHVGHPEGYTATDIIS  62
            Y    IE KWQ +W +++TF+T T++SKPK+Y LDMFPYPSGAGLHVGHPEGYTATDI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RLKRMEGYEVLHPMGWDAFGLPAERYAMTTGIHPRTTTKNNIDTFRRQIKSLGLSYDWER  122
            R+KR +G +VLHPMGWDAFGLPAE+YAM TG +P   T +NI  F+RQI++LG+SYDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EISTTHPDYYRWTQWIFLQIYN  144
            E++TT+P+YY+WTQWIF ++Y+
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYE  145

943) leuS in NC_003910


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  554 bits (2093),  Expect = 7e-159, Method: Compositional matrix adjust.
 Identities = 367/871 (43%), Positives = 573/871 (66%), Gaps = 49/871 (5%)

Query  3    AIYNPQAIEATVQKFWTDNNTFQAIENPDKEKFYCLAMFPYPSGR-LHMGHVRNYSLGDV  61
            ++Y+  AIE+  Q FW+DN+TF++  ++ K KFY L MFPYPSG  LH+GH   Y+  D+
Sbjct  2    TFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDI  61

Query  62   ISRYQRMQGKNVMQPMGWDAFGLPAENAAIKNKTAPGKWTYENIDYMRNQLQSLGFGYDW  121
            +SR++R QG NV++PMGWDAFGLPAE+ A+     P+  T ENI   + Q+++LGF+YDW
Sbjct  62   LSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDW  121

Query  122  GRELATCKPDYYRWEQWFFTQLFEKGLVYKKNATVNWDPVDQTVLANEQVI-DGRGWRSG  180
            +RE+ T  P+YY+W QW+FT+L+EKGL Y  +  VNW     T +ANE+V+ DG + R+G
Sbjct  122  DREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGG  181

Query  181  ALVERKQIPQWFIKITDYAEEllddldQLTEWPEQVKTMQRNWIGRSQGVEMTFAVADST  240
              V RK + QW +KIT YAE LL+DL+++ +WPE +K MQRNWIG+S G ++TF V D+ 
Sbjct  182  YPVVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  241  ESFDIYTTRPDTLMGVTYvalaaqhplavaaavdnadlaaFIDECKNSKTTEADMA----  296
              F ++TTRPDTL G TY  LA++H+L  A +  +   A  + + K   +  +D+A    
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEA--VADYKRQASLKSDLARTDL  298

Query  297  AMEKKGVDTGLKAIHPLTGKLVPVWAANFVLMDYGSGAVMSVPGHDQRDYEFALKYGLAI  356
            A EK GV TG  AI+P+ GK +PVW A++VL  YG+GA+M+VP+HD+RD EFA ++ L I
Sbjct  299  AKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDI  358

Query  357  EQVIAGQEADDINKAAITEKSTLINSGEFDGLDFEEAFKAISDKLISENKGKTTTNYRLR  416
              V+ G   ++++ AA+TE +  INS+ +DGLD   A+  + + L +E  G+    YRLR
Sbjct  359  IPVLEG---GNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  417  DWGVSRQRYWGTPIPMINLANGESVPVPTNELPVVLP--EDVVMNGTT-SPIKADPEWAK  473
            DW  SRQRYWG PIP+I+  +G S +VP +ELP+VLP   D+  +GT  SP+    +W  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  474  -TLYNGEEALRETDTFDTFMESSWYYARYCSPNDDTQMIDPAKANYWLPVDQYIGGIEHA  532
             T  +G  + RET+T      SSWYY RY  P++  ++ D    + WLPVD Y+GG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  533  ILHLLYSRFFHKLLRDVGLVKCDEPFKKLLCQGMVLAETYYREADNGAQEWIAPTDVEVE  592
            +LHLLY+RF HK+L D+G+V   EPF+KL+ QGM+L+ + YR++  +         V  +
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS-YRDSRGAL--------VATD  586

Query  593  RDEKGQITSSISKIDGQPVLSAGMSKMSKSKNNGIDPQEVIEKYGADTVRLFIMFTSPPE  652
            + EK +  +S+  ++    L  + +KMSKS +N ++P++V+E+YGADT+R++ MF +P +
Sbjct  587  KVEKRD--GSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLD  644

Query  653  QTLEWSDAGVEGAHRFVKRVYKLAHEFVESTNNSAVVDIAELTLNADHKKLRRELHKTIA  712
             ++ WS+ G+EG+++F+ RVY+L             +   E+T + +   L +  + T+ 
Sbjct  645  ASIAWSEEGLEGSRKFLDRVYRL-------------ITTKEIT-EENSGALDKVYNETVK  690

Query  713  KVTDDIGRRNTFNTAIAAIMELMNHLGKAKVNSDEDKAVMQEAVRAVVLMLTPITPHLCH  772
             VT+++++ + FNTAIA +M ++N        ++ +  +  +  ++ V +++P++PHL +
Sbjct  691  AVTEQVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGE  742

Query  773  HLWQLVGGSDENVEDASWPVVDNSALVEDEKLIIVQVNGKVRAKITVAADASKEDVEALG  832
            +LWQ + +S+E++   +WP  D+S LVE++  I+VQ++GKV+AK+ VA D S+E+++ ++
Sbjct  743  ELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVA  802

Query  833  LNDESVLKFTDGNTIRKVIYIPGKLLNIVAN  863
            L +E V     G+ I KVI +P KL+NIV +
Sbjct  803  LANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

944) MHP168L_657 in NC_021283


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  554 bits (2093),  Expect = 7e-159, Method: Compositional matrix adjust.
 Identities = 359/842 (43%), Positives = 558/842 (67%), Gaps = 69/842 (8%)

Query  3    DHRAIEKKWQDYWYKNKVFKT-TETSRKKAYILDMFPYPSASGLHLGHPIGYTASDIVAR  61
            DH AIE KWQ +W  N  FKT T++S+ K Y LDMFPYPS++GLH+GHP GYTA+DI++R
Sbjct  5    DHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSR  64

Query  62   FKRLNGFDVLHPMGWDAFGLPAEQYAIKTGNHPGEFTKRNIENFKKQIISFGFSYDWDKE  121
            FKR +G +VLHPMGWDAFGLPAEQYA+ TGN+P+EFT  NI NFK+QI ++GFSYDWD+E
Sbjct  65   FKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDRE  124

Query  122  INTSDPEFYVQTQWIFKLLYKANLAEIREVEVNWCPELGTVLANEELKREKNGALVSERG  181
            +NT+DP++Y  TQWIF  LY   LA   EV VNW  ELGT +ANEE+  +      SERG
Sbjct  125  VNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGT----SERG  180

Query  182  NFPVILKKMKQWVLKITEYAQKLLDGLDQVDFPDSLKTLQkkwigkskgwkikFLIEKTG  241
             +PV+ K M+QW+LKIT YA++LL++L++VD P+S+K +Q++WIGKS G ++ F +  T+
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  242  EFLEIFTTKIETFYGVSFLALAPLHNFAQKLAKNN--EKISQFIEQNSFSS----PKLQS  295
              + +FTT+ +T++G ++  LAP H + + ++ ++  E ++++  Q S+ S      L  
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  296  KMTGIFTGLYAVHPLNSSKIPIYIANYVLNNYATSAIMGVPGHNLADLEFAQIFQIDYVK  355
              TG+ TG YA++P+N+  +P+ IA+YVL +Y+T+AIM+VP+H+  D EFA+ F++D + 
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  356  LID----------QENLLINSAEFSGLTIKEGANSIFNKLNSMNLVQKTTIFRLKDWVFS  405
            +++          ++ L INS  + GL    +   + + L++  + +    +RL+DW+FS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  406  RQRYWGEPFP-VYFDEKGKIYLEEKIVE--LPHTDKIMPSGDGQSPLASIKDWVFFEK-N  461
            RQRYWGEP+P +  ++     + E  +   LP T  I PSG G+SPLA++ DW+   + +
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  462  GKYYRRETNTMPQWSGSSWYYLAFILKEKDKYLPLDSKIAYDKFKKWLPVDLYIGGQEHA  521
            G   RRETNTMPQW+GSSWYYL +I  ++   L+ +     + +K+WLPVD+Y+GG EHA
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADE-----ELLKQWLPVDIYVGGAEHA  535

Query  522  VGHLIYSRFWHRVLFDAGIVPNSEPFQKIIHQGMLLGS----------------------  559
            V HL+Y+RFWH+VL+D G+VP  EPFQK+++QGM+LG+                      
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSF  595

Query  560  -----------DGQKMSKSKGNTINPTEMIDKFGADTIRIFLMFMGPIGDLRLWDENGVV  608
                          KMSKS  N +NP ++++++GADT+R++ MFMGP++    W E+G+ 
Sbjct  596  FHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLE  655

Query  609  SIFNWIQRVQRTILADYEIDPELEKDYEFTYFFNNFVFEITNLIETFKFNVAISKLMVYI  668
            +  + ++RV R I +  EI  E     +  Y  N+ V  +T+ ++  KFN AI++LMV++
Sbjct  656  GSRKFLDRVYRLITTK-EITEENSGALDKVY--NETVKAVTEQVDQMKFNTAIAQLMVFV  712

Query  669  NFLNKKQKIPSKNYLTDFLIIFSVFAPHTAEELLEKL--GQKPLNFQIWPQFDRSKIFKN  726
            N  NK +K+ S +Y  +F+ +++ FAPH +EEL + L  +  ++++  WP +D SK+  N
Sbjct  713  NAANKEDKLFS-DYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVEN  771

Query  727  TFHLPVSINGKNRGILELTDEKSQEEIIEIAKKDYKIRNYLQNKQIIKVIYIPRKILNFI  786
              ++ V I+GK ++ L ++ + S+EE+ E+A  + K++  +  K+IIKVI +P K++N++
Sbjct  772  DVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIV  831

Query  787  LK  788
            +K
Sbjct  832  IK  833

945) leuS in NC_017509


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  554 bits (2093),  Expect = 7e-159, Method: Compositional matrix adjust.
 Identities = 359/842 (43%), Positives = 558/842 (67%), Gaps = 69/842 (8%)

Query  3    DHRAIEKKWQDYWYKNKVFKT-TETSRKKAYILDMFPYPSASGLHLGHPIGYTASDIVAR  61
            DH AIE KWQ +W  N  FKT T++S+ K Y LDMFPYPS++GLH+GHP GYTA+DI++R
Sbjct  5    DHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSR  64

Query  62   FKRLNGFDVLHPMGWDAFGLPAEQYAIKTGNHPGEFTKRNIENFKKQIISFGFSYDWDKE  121
            FKR +G +VLHPMGWDAFGLPAEQYA+ TGN+P+EFT  NI NFK+QI ++GFSYDWD+E
Sbjct  65   FKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDRE  124

Query  122  INTSDPEFYVQTQWIFKLLYKANLAEIREVEVNWCPELGTVLANEELKREKNGALVSERG  181
            +NT+DP++Y  TQWIF  LY   LA   EV VNW  ELGT +ANEE+  +      SERG
Sbjct  125  VNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGT----SERG  180

Query  182  NFPVILKKMKQWVLKITEYAQKLLDGLDQVDFPDSLKTLQkkwigkskgwkikFLIEKTG  241
             +PV+ K M+QW+LKIT YA++LL++L++VD P+S+K +Q++WIGKS G ++ F +  T+
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  242  EFLEIFTTKIETFYGVSFLALAPLHNFAQKLAKNN--EKISQFIEQNSFSS----PKLQS  295
              + +FTT+ +T++G ++  LAP H + + ++ ++  E ++++  Q S+ S      L  
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  296  KMTGIFTGLYAVHPLNSSKIPIYIANYVLNNYATSAIMGVPGHNLADLEFAQIFQIDYVK  355
              TG+ TG YA++P+N+  +P+ IA+YVL +Y+T+AIM+VP+H+  D EFA+ F++D + 
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  356  LID----------QENLLINSAEFSGLTIKEGANSIFNKLNSMNLVQKTTIFRLKDWVFS  405
            +++          ++ L INS  + GL    +   + + L++  + +    +RL+DW+FS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  406  RQRYWGEPFP-VYFDEKGKIYLEEKIVE--LPHTDKIMPSGDGQSPLASIKDWVFFEK-N  461
            RQRYWGEP+P +  ++     + E  +   LP T  I PSG G+SPLA++ DW+   + +
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  462  GKYYRRETNTMPQWSGSSWYYLAFILKEKDKYLPLDSKIAYDKFKKWLPVDLYIGGQEHA  521
            G   RRETNTMPQW+GSSWYYL +I  ++   L+ +     + +K+WLPVD+Y+GG EHA
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADE-----ELLKQWLPVDIYVGGAEHA  535

Query  522  VGHLIYSRFWHRVLFDAGIVPNSEPFQKIIHQGMLLGS----------------------  559
            V HL+Y+RFWH+VL+D G+VP  EPFQK+++QGM+LG+                      
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSF  595

Query  560  -----------DGQKMSKSKGNTINPTEMIDKFGADTIRIFLMFMGPIGDLRLWDENGVV  608
                          KMSKS  N +NP ++++++GADT+R++ MFMGP++    W E+G+ 
Sbjct  596  FHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLE  655

Query  609  SIFNWIQRVQRTILADYEIDPELEKDYEFTYFFNNFVFEITNLIETFKFNVAISKLMVYI  668
            +  + ++RV R I +  EI  E     +  Y  N+ V  +T+ ++  KFN AI++LMV++
Sbjct  656  GSRKFLDRVYRLITTK-EITEENSGALDKVY--NETVKAVTEQVDQMKFNTAIAQLMVFV  712

Query  669  NFLNKKQKIPSKNYLTDFLIIFSVFAPHTAEELLEKL--GQKPLNFQIWPQFDRSKIFKN  726
            N  NK +K+ S +Y  +F+ +++ FAPH +EEL + L  +  ++++  WP +D SK+  N
Sbjct  713  NAANKEDKLFS-DYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVEN  771

Query  727  TFHLPVSINGKNRGILELTDEKSQEEIIEIAKKDYKIRNYLQNKQIIKVIYIPRKILNFI  786
              ++ V I+GK ++ L ++ + S+EE+ E+A  + K++  +  K+IIKVI +P K++N++
Sbjct  772  DVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIV  831

Query  787  LK  788
            +K
Sbjct  832  IK  833

946) leuS in NC_007295


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  554 bits (2092),  Expect = 8e-159, Method: Compositional matrix adjust.
 Identities = 358/842 (43%), Positives = 556/842 (67%), Gaps = 69/842 (8%)

Query  3    DHRAIEKKWQDYWYKNKVFKT-TETSRKKAYILDMFPYPSASGLHLGHPIGYTASDIVAR  61
            DH AIE KWQ +W  N  FKT T++S+ K Y LDMFPYPS++GLH+GHP GYTA+DI++R
Sbjct  5    DHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSR  64

Query  62   FKRLNGFDVLHPMGWDAFGLPAEQYAIKTGNHPGEFTKRNIENFKKQIISFGFSYDWDKE  121
            FKR +G +VLHPMGWDAFGLPAEQYA+ TGN+P+EFT  NI NFK+QI ++GFSYDWD+E
Sbjct  65   FKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDRE  124

Query  122  INTSDPEFYVQTQWIFKLLYKANLAEIREVEVNWCPELGTVLANEELKREKNGALVSERG  181
            +NT+DP++Y  TQWIF  LY   LA   EV VNW  ELGT +ANEE+  +      SERG
Sbjct  125  VNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGT----SERG  180

Query  182  NFPVILKKMKQWVLKITEYAQKLLDGLDQVDFPDSLKTLQkkwigkskgwkikFLIEKTG  241
             +PV+ K M+QW+LKIT YA++LL++L++VD P+S+K +Q++WIGKS G ++ F +  T+
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  242  EFLEIFTTKIETFYGVSFLALAPLHNFAQKLAKNK--EKISQFIEQNSFSS----PKLQS  295
              + +FTT+ +T++G ++  LAP H + + ++ +   E ++++  Q S+ S      L  
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  296  KMTGIFTGLYAVHPLNSSKIPIYITNYVLNNYATSAIMGVPAHNLADLEFAQIFQIDYVK  355
              TG+ TG YA++P+N+  +P+ I++YVL +Y+T+AIM+VPAH+  D EFA+ F++D + 
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  356  VIN----------QENLLINSAEFSGLTIKEGANSIFSKLNSMNLVQKTTIFRLKDWVFS  405
            V++          ++ L INS  + GL    +   +   L++  + +    +RL+DW+FS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  406  RQRYWGEPFP-VYFDEKGKIYLEEKIVE--LPHTDKIMPSGDGQSPLASIKDWVFFEK-N  461
            RQRYWGEP+P +  ++     + E  +   LP T  I PSG G+SPLA++ DW+   + +
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  462  GKYYRRETNTMPQWSGSSWYYLAFILKEKDKYLPLDSKIAYDKFKKWLPVDLYIGGQEHA  521
            G   RRETNTMPQW+GSSWYYL +I  ++   L+ +     + +K+WLPVD+Y+GG EHA
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADE-----ELLKQWLPVDIYVGGAEHA  535

Query  522  VGHLIYSRFWHKVLFDAGIVPNSEPFQKIIHQGMLLGSD---------------------  560
            V HL+Y+RFWHKVL+D G+VP  EPFQK+++QGM+LG+                      
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSF  595

Query  561  ------------GQKMSKSKGNTINPTEIIDKFGADTIRIFLMFMGPIGDLRLWDENGVV  608
                          KMSKS  N +NP ++++++GADT+R++ MFMGP++    W E+G+ 
Sbjct  596  FHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLE  655

Query  609  SIFNWIQRVQRTILADYKIDPELEKDYEFTYFFNNFVFEITNLIETFKFNVAISKLMVYI  668
            +  + ++RV R I +    +   E+   +   +N+ V  +T+ ++  KFN AI++LMV++
Sbjct  656  GSRKFLDRVYRLITTKEITE---ENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFV  712

Query  669  NFLNKKQKIPSKNYLTDFLIIFSVFAPHTAEELLEKL--GQKPLNFQIWPQFDRSKIFKN  726
            N  NK +K+ S +Y  +F+ +++ FAPH +EEL + L  +  ++++  WP +D SK+  N
Sbjct  713  NAANKEDKLFS-DYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVEN  771

Query  727  TFHLPVSINGKNRGILELTDEKSQEEIIEIAKKDYKIRNYLQNKQIIKVIYIPRKILNFI  786
              ++ V I+GK ++ L ++ + S+EE+ E+A  + K++  +  K+IIKVI +P K++N++
Sbjct  772  DVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIV  831

Query  787  LK  788
            +K
Sbjct  832  IK  833

947) leuS in NC_018632


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  554 bits (2092),  Expect = 8e-159, Method: Compositional matrix adjust.
 Identities = 361/874 (42%), Positives = 559/874 (64%), Gaps = 56/874 (6%)

Query  6    YNPKDIEQRVQQYWEENQSFKANDDVEKEKFYCLSMFPYPSGR-LHMGHVRNYTIGDVIS  64
            Y+   IE + Q +W +N++FK+  D  K KFY L MFPYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  65   RFQRMQGKNVLQPMGWDAFGLPAENAAINNNTAPAKWTYSNIDYMKNQLRSLGFGYDWDR  124
            RF+R QG NVL+PMGWDAFGLPAE+ A++    PA  T  NI   K Q+ +LGF+YDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  125  EVTTCKSDYYRWEQWFFTRLYEKGLVYKKNSTVNWDPVDQTVLANEQVI-DGRGWRSGAL  183
            EV T  ++YY+W QW+FT+LYEKGL Y  +  VNW     T +ANE+V+ DG + R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  184  VEQKEIPQWFIKITDYAeellqdleqleeWPDQVRAMQANWIGRSEGVEITFDLASAVND  243
            V +K + QW +KIT YA E L +  +  +WP+ ++ MQ NWIG+S G ++TF +  + + 
Sbjct  184  VVRKPMRQWMLKITAYA-ERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDK-  241

Query  244  IADLTVYTTRPDTFYGVTYVAVAAQHPLAEFAAKSNPDLAAFIDECKNTKVAEAELA---  300
              D+TV+TTRPDT++G TY  +A++H+L +  A + +D A  + + K      ++LA   
Sbjct  242  --DFTVFTTRPDTLFGATYAVLAPEHALVD--AITTSDQAEAVADYKRQASLKSDLARTD  297

Query  301  -TMEKKGFATGFEVVHPLTGEKLPIWVANFVLMDYGSGAVMAVPGHDQRDWEFATKYNLP  359
             + EK G  TG   ++P+ G  +P+W+A++VL  YG+GA+MAVP+HD+RDWEFA ++NL 
Sbjct  298  LAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLD  357

Query  360  IQQVIAPNAGDEDKCDLTASAFTEKGSLINSYKFDGLEFDAAFNGIADELESKGCGKRKV  419
            I  V+     +E       +AFTE G  INS  +DGL+  +A+  + + LE+ G G+ +V
Sbjct  358  IIPVLEGGNVEE-------AAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENV  410

Query  420  NYRLRDWGVSRQRYWGAPIPMLNLENGESVPVPADQLPVVLP--EDVEMNGVT-SPIKAD  476
             YRLRDW  SRQRYWG PIP+++ E+G S +VP  +LP+VLP   D+  +G   SP+   
Sbjct  411  TYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANV  470

Query  477  PEWAKTTY-NGEAALRETDTFDTFMESSWYYARYACATNNDAMLDPTSANYWLPVDQYIG  535
             +W   T  +G  + RET+T      SSWYY RY  + N + + D    + WLPVD Y+G
Sbjct  471  TDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVG  530

Query  536  GIEHAILHLLYSRFFHKLLRDEGLVNSDEPFKRLLCQGMVLADSYYREDASGKKTWFSPT  595
            G EHA+LHLLY+RF HK+L D G+V + EPF++L+ QGM+L+ S YR+  ++        
Sbjct  531  GAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS-YRDSRGAL-------  582

Query  596  EVSTEKDDKGRIVKAWLTADGEEVIHGGMTKMSKSKNNGIDPQEVIDQYGADTVRLFTMF  655
             V+T+K +K     + +  +  E ++ + +KMSKS +N ++P++V++QYGADT+R++ MF
Sbjct  583  -VATDKVEKRD--GSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMF  639

Query  656  AAPPEQTLEWVDSGVEGANRFLRRIWKLVTEHVEKGTPEAIDVKALSKDQQ-ALRREVHK  714
             +P + ++ W + G+EG+ +FL R+ +L+T             K ++ ++  AL +  + 
Sbjct  640  MGPLDASIAWSEEGLEGSRKFLDRVYRLIT------------TKEITEENSGALDKVYNE  687

Query  715  TIEKVSDDLGRRQTFNTAVAAVMELLNHLQKAPQENAQDIAIMREACESILLLLNPITPH  774
            T+  V++++++ + FNTA+A +M ++N  +K  +       +  +   +++ L+ P++PH
Sbjct  688  TVKAVTEQVDQMK-FNTAIAQLMVFVNAANKEDK-------LFSDYAKGFVQLIAPFAPH  739

Query  775  IAHELWKVL-GHSEDIDLAPWPQADKAALVEDEKLIIVQVNGKVRAKMTIAADASKESIE  833
            +++ELW+ L + +E I   PWP  D + LVE++  I+VQ++GKV+AK+ +A D S+E ++
Sbjct  740  LGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQ  799

Query  834  ASAKEQPNVQQFIEGKTIRKVIVVPGKLVNIVAN  867
              A  + +VQ  I GK I KVI VP KLVNIV +
Sbjct  800  EVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

948) leuS in NC_010424


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  554 bits (2092),  Expect = 9e-159, Method: Compositional matrix adjust.
 Identities = 373/863 (44%), Positives = 564/863 (66%), Gaps = 74/863 (8%)

Query  5    YVFAEIEEKLRRRWETEGIYHVPDFSNRPKYYCLEMFPYPSG-NLHMGHVRNYAIGDVVA  63
            Y  + IE K +  W  +  +     +++PK+Y L+MFPYPSG  LH+GH   Y+  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RFKTMRGYDVLHPMGWDAFGLPAENAAIQHGVPPARWTWDNINVMRTQLKLLGVSYDWRR  123
            RFK  +G +VLHPMGWDAFGLPAE+ A++ G  PA  T +NI   + Q++ LG SYDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCHPGYYRWTQWLFLQFYHRGLAYKAKAPVNWCPSCATVLANEQVVAGG-CERCKTA  182
            E+ T +P YY+WTQW+F ++Y++GLAY A  PVNW    +T +ANE+V+++G  ER   +
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERRELEQWFFRITAYADRLLKDLAKLPGWPEKVKVMQENWIGRSTGAEIAFPLAGTDEA  242
            V R+ + QW ++ITAYA+RLL DL  + +WPE +K MQ NWIG+STGA+++F + +TD  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  IRVFTTRPDTLGGVTYMTIAPEHPLVSRVTTPEHRAAVEAFTERARSLSELDRTAGEHEK  302
            + VFTTRPDTL G TY  +APEH+LV  +TT+++  AV  +  +A   S+L RT    EK
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEK  302

Query  303  EGLFTGAYCVNPLTGEQVPVFVANYVLMEYGTGCVMGVPAHDQRDFEFARKYGLPVRVVI  362
             G+ TG+Y +NP+ G ++PV +A+YVL  YGTG +M+VPAHD+RD EFA+++ L +  V+
Sbjct  303  TGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL  362

Query  363  QPEGDLLDGDTMSQAYTGPGRLVNTPGFDRMANAEAIPAITRYLEARGAARFQVQYRLRD  422
            +      +G+    A+T  G  +N+  +D + +A AI+ +   LEA G +  +V YRLRD
Sbjct  363  E------GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  423  WLISRQRYWGAPIPIVYcegcgvvpvpeeglpvllpeDVAFKP--TGRSPLTESPDFVNT  480
            WL+SRQRYWG PIPI+  E+    +VPE  LP++LP    ++P  TG SPL++  D ++ 
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  481  TCPTCGGPARRETDTMDTFMCSSWYYFRFTSPREENGPWGLERVDRWLPVDQYIGGVEHA  540
            T    G  +RRET+TM     SSWYY+R+  P++ +   + E + +WLPVD Y+GG EHA
Sbjct  477  TRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  541  ILHLMYSRFFTKVLYDMGLVKVQEPFTNLLTQGMVL-------------------KDG--  579
            +LHL+Y+RF  KVLYD+G+V  +EPF +L+ QGM+L                   +DG  
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSF  595

Query  580  -------------AKMSKSKGNVVSPEDILNRYGADTTRLFVLFAAPPERDLEWSDQGVE  626
                         AKMSKS  NVV+P+D++++YGADT R++ +F +P +  + WS++G+E
Sbjct  596  FHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLE  655

Query  627  GCYRFLQRVWRLVNS--VADEIRGAAPVPSANLVGVNRSMRRLTHQTIKKVTEDIETRFN  684
            G  +FL+RV RL+ +  +++E  GA              + ++ ++T+K VTE+++ + +
Sbjct  656  GSRKFLDRVYRLITTKEITEENSGA--------------LDKVYNETVKAVTEQVD-QMK  700

Query  685  FNTAISAAMELVNGMYHFRDRVAPVNRDPAVMREAVERlllllapfapflaDELW-ARTG  743
            FNTAI+  M +VN+           N++  +  +    ++ L+APFAP L++ELW A T+
Sbjct  701  FNTAIAQLMVFVNA----------ANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTA  750

Query  744  HPESIHREPWPEYDPELLVEDQVEIVVQINGRVRDRLMVAADIAPEAMRDTVLEQPRVQA  803
              ESI   PWP YD   LVE++VEIVVQI+G+V+ +L+VA D++ E +++  L + +VQA
Sbjct  751  SGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQA  810

Query  804  LVAGKEIVKVVPVPGKLVNIVVR  826
             +AGK+I+KV++VP KLVNIV++
Sbjct  811  EIAGKDIIKVIAVPNKLVNIVIK  833

949) leuS in NC_018681


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  554 bits (2092),  Expect = 9e-159, Method: Compositional matrix adjust.
 Identities = 399/930 (43%), Positives = 586/930 (64%), Gaps = 113/930 (12%)

Query  24   IEARWQRTWADRGTFHAPNPVGPLAGDTPADKLFIQDMFPYPSGAGLHVGHPLGYIATDT  83
            IE++WQ  WAD  TF +       + D++  K++  DMFPYPSGAGLHVGHP GY ATD 
Sbjct  9    IEPKWQAFWADNHTFKT-------GTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDI  61

Query  84   FARYHRMHGRNVLHALGFDAFGLPAEQYAVQTGAHPRVTTESNIANMQRQLSRLGLGHDS  143
            ++R+ R +G+NVLH++G DAFGLPAEQYA++TG +P   T  NIAN +RQ++ LG++ D 
Sbjct  62   LSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDW  121

Query  144  RRSFATTDPAYYRWTQWIFLRIYNS--WYDQELDRARPITELEAQFASGARPVPDGKTWD  201
             R   TTDP YY+WTQWIF ++Y+    Y+ E+   + + EL + +A+    +PDG    
Sbjct  122  DREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNW-VEELGTAIANEE-VLPDG----  175

Query  202  GLSATERGALLDSYRLVYLTDSMVNWCPGLGTVLSNEEVTADGRSERGNFPVFRKRLWQW  261
               ++ERG+    Y +V    +M +W      +L              ++  +  RL   
Sbjct  176  ---TSERGG----YPVV--RKPMRQW------ML--------------KITAYAERL---  203

Query  262  MMRITAYADRLIDDLDHLDWSDQVKAMQRNWIGRSRGAQVKFDV--AGEQIEVFTTRPDT  319
                       ++DL+++DW++ +K MQRNWIG+S GA+V F V  ++ ++ VFTTRPDT
Sbjct  204  -----------LEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDT  252

Query  320  LFGATYVVLAPEHELVDKLTAAAWPDGTDPRWTNGGaanpadavaaYRKSIVAKSDLERQ  379
            LFGATY VLAPEH LVD +T++  +++                   Y++    KSDL R 
Sbjct  253  LFGATYAVLAPEHALVDAITTSDQAEAVA----------------DYKRQASLKSDLART  296

Query  380  E-NKEKTGVFLGVHAVNPANGRAVPVFVADYVLSGYGTGAIMAVPGHDQRDWEFATVLGL  438
            +  KEKTGV  G  A+NP NG+ +PV +ADYVL++YGTGAIMAVP+HD+RDWEFA  + L
Sbjct  297  DLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNL  356

Query  439  PIVEVITGGDLAEAAYSGDGALVNSGYLDGLSVEEAKATIIARLEADGHGTGTIQYKLRD  498
             I+ V+ GG++ EAA++ DG  +NS++LDGL    A A ++ +LEA+G G   + Y+LRD
Sbjct  357  DIIPVLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  499  WLFARQRYWGEPFPIVFDEDGRPHALPESMLPVELPELDDFAPVTFdpddadsepsppLA  558
            WLF+RQRYWGEP+PI+  EDG + A+PES LP+ LP   D+ P             +PLA
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSG--------TGESPLA  468

Query  559  KATEWVNVELDLGDGPKMYRRDTNVMPNWAGSSWYQLRYADPTNPEAFCAKENEQYWLGP  618
            + T+W++V  +  DG K  RR+TN MP+WAGSSWY LRY DP N E +   E  + WL  
Sbjct  469  NVTDWLEVTRE--DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWL--  523

Query  619  RPAEHGPDDPGGVDLYIGGMEHAVLHLLYARFWQKVLFDLGDVSGREPYRKLFNQGYIQA  678
                        VD+Y+GG EHAVLHLLYARFW+KVL+DLG V+ +EP++KLFNQG I +
Sbjct  524  -----------PVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILG  572

Query  679  YAYTDARGAYVPAAEIVERDGKFFWTEPGGTEIEVFQEYGKIGKSLKNAVSPDEMYDLYG  738
             +Y D+RGA V++  +  RDG FF  E G    E+ Q  +K++KSLKN V+PD++ + YG
Sbjct  573  TSYRDSRGALVATDKVEKRDGSFFHVETGE---ELEQAPAKMSKSLKNVVNPDDVVEQYG  629

Query  739  ADTFRFYEMSMGPLDSSRPWATKDVVGAHRFLQRVWRLVVDEETGAVRVAELDPTPETLR  798
            ADT+R YEM MGPLD+S +W+  ++ G+++FL+RV RL+   E      + LD      +
Sbjct  630  ADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALD------K  683

Query  799  LLHKTIAGVDEDYAALRDNTAGAKLIELTNHLTKTYPDGAPRAVVEALVLMLAPLSPHIA  858
            + + T+ +V E+   ++ NTA A+L+ + N   K   D        ++V ++AP++PH++
Sbjct  684  VYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKE--DKLFSDYAKGFVQLIAPFAPHLG  741

Query  859  EEMWERL-GHNESLAHGPFPVADPALLVQESVEYPIQVNGKVRSRIQVPadadnaaieaa  917
            EE+W+ L +  ES++  P P  D + LV++ VE  +Q++GKV++++ V+ D     ++  
Sbjct  742  EELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEV  801

Query  918  aLTDEKIAALLNGAAPRKLIVVPGRLINIV  947
            AL++EK+ A + G    K+I VP +L+NIV
Sbjct  802  ALANEKVQAEIAGKDIIKVIAVPNKLVNIV  831

950) leuS in NC_020211


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  554 bits (2091),  Expect = 9e-159, Method: Compositional matrix adjust.
 Identities = 361/866 (42%), Positives = 558/866 (65%), Gaps = 48/866 (5%)

Query  5    YRPEDIESNVQLHWQEKQTFKVTEDDSKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIS  63
            Y    IE++ Q  W +++TFK   D SK K+Y L M+PYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIEYMKNQLKLLGFGYDWDR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NI   K Q++ LGF+YDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EIATCQPEYYRWEQWFFTKLYEKGLVYKKTSAVNWCPHDLTVLANEQVI-DGCCWRCDTK  182
            E+ T +P+YY+W QW+FTKLYEKGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADQLLNDLDTLESWPEQVKTMQRNWIGRSEGVEITFDVADSEEK  242
            V RK + QW +KITAYA++LL+DL+ ++ WPE +K MQRNWIG+S G ++TF V D++  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGATYVAVAAGHPLAQQGARNNPALTEFIDECRNTKVAEAEMA----TM  298
            +TV+TTRPDT+ GATY  +A+ H+L +  + ++ A  E + + +      +++A    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQA--EAVADYKRQASLKSDLARTDLAK  300

Query  299  EKKGMPTGLFVVHPLSGEKLPVWVANFVLMEYGTGAVMAVPAHDQRDWEFATKYDLPIKP  358
            EK G+ TG + ++P++G  +PVW+A++VL  YGTGA+MAVPAHD+RDWEFA +++L I P
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VILNLDGSQPDVSAEAMTDKGALFNSGEFDGLDNEAGFNAIADKLVAKGVGQRKVNYRLR  418
            V   L+G+  +V   A T+ G  +NS+ +DGLD+ +++  + + L A GVG+ +V YRLR
Sbjct  361  V---LEGG--NVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  419  DWGVSRQRYWGAPIPMVTLEDGTVMPTPEDQLPVILP--EDVVMDGIT-SPIKADPEWAK  475
            DW  SRQRYWG PIP++  EDGT  + PE +LP++LP   D+   G   SP+    +W  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  476  TT-VDGQPALRETDTFDTFMESSWYYARYTCPQYDQGMLDPAAANYWLPVDQYIGGIEHA  534
             T  DG  + RET+T      SSWYY RY  P+  + + D    + WLPVD Y+GG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  535  IMHLMYFRFFHKLMRDAGLVDSDEPAKRLLCQGMVLADAFYYTGNSGERVWVSPVDATVE  594
            ++HL+Y RF HK++ D G+V + EP ++L+ QGM+L+ +  Y ++ G  V        VE
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS--YRDSRGALV----ATDKVE  589

Query  595  RDDKGRIIKATDPQGRELVYAGMSKMSKSKNNGIDPQEMVEKYGADTVRLFMMFASPAEM  654
            + D G ++     +  E    + +KMSKS +N ++P+++VE+YGADT+R++ MF +P + 
Sbjct  590  KRD-GSFFHVETGEELE---QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  655  TLEWQESGVEGANRFLKRVWKLAYDHVEKGAVQPLDVASLNEEQKALRRDLHKTIAKVTD  714
            ++ W E G+EG+ +FL RV +L         +   +++  +E+  AL +  + T+  VT+
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRL---------ITTKEIT--EENSGALDKVYNETVKAVTE  694

Query  715  DIGRRQTFNTAIAAVMELMNKLARAPQESEQDRALLQEALLAVVRMLYPFTPHVCFTLWQ  774
            ++++ + FNTAIA +M ++N        ++++  L+ +   + V+++ PF+PH+   LWQ
Sbjct  695  QVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  775  ALGGEGD-VDTAPWPVADEQAMVEDSKLVVVQVNGKVRAKITVSADATEEQVRARAAEEH  833
            AL + G+ +   PWP  DE  +VE+   +VVQ++GKV+AK+ V+ D + E+++  A  ++
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  834  LVAKYLDGVTIRKVIYVPGKLLNLVV  859
             V   + G  I KVI VP KL+N+V+
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVI  832

951) syl in NC_018604


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  554 bits (2092),  Expect = 9e-159, Method: Compositional matrix adjust.
 Identities = 352/865 (41%), Positives = 557/865 (65%), Gaps = 49/865 (5%)

Query  3    YNFTTIEKKWQKYWKDNQSFKTVSKPTDKKYYVLEMFPYPSGK-MHMGHVSNYTIADSIA  61
            Y+ T+IE KWQ +W DN++FKT + ++  K+Y L+MFPYPSG  +H+GH   YT +D ++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  62   RYYKLLGYDILHPMGWDAFGMPAENAAIDNKTHPAEWTLKNIANMKDQLNLLGYSYDWDR  121
            R+ +  G ++LHPMGWDAFG+PAE+ A+D   +PAE T  NIAN K Q+N LG+SYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  122  EVTTCLPDYYKWGQWFILKMYEKGLLYRKGGDVNWCDHCNTVLANEQVTAEGTCWRCDGE  181
            EV T  P+YYKW QW++ K+YEKGL Y     VNW ++  T +ANE+V ++GT  R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VTKKKLEQWYIKVTDYAEQLDADLKLLEGYWPDNVIAMQKNWIGRSVGAYINFNL-DDGK  240
            V +K + QW +K+T YAE+L  DL  ++  WP+++  MQ+NWIG+S GA + F++ D +K
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD--WPESIKDMQRNWIGKSTGANVTFKVKDTDK  241

Query  241  DFPIFTTRPDTIYGVTYMAIAWNYDGLLD-MCTPEQKNAVEEFIKKSA-KID-QKTDYEK  297
            DF +FTTRPDT++G TY  +A   ++L+D + T++Q +AV ++ ++++ K D  +TD  K
Sbjct  242  DFTVFTTRPDTLFGATYAVLA-PEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  298  E--GVFTGRYVVNPFNGEKAPLYAANFVLAEYGSGAVMAVPAHDQRDFEFAKKYNIPVKV  355
            E  GV TG Y +NP NG   P+  A++VLA YG+GA+MAVPAHD+RD EFAK++N+ +  
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  356  VIQNADNSIKAETMTEAYVEDGIVVNSDILNGLSSRDAIKRAIEYATEKGFGKEKVQYKL  415
            V++ ++          A+ EDG+ +NSD+L+GL    AI + +E     G G+E+V Y+L
Sbjct  361  VLEGGNVE------EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRL  414

Query  416  RDWLISRQRYWGNPLPFVHCEKCGVVPVPESELPITLPMDIEF---TVGENPLKKSASFV  472
            RDWL+SRQRYWG+P+P++H E     +VPESELP+ LP+  ++     GE+PL + +  +
Sbjct  415  RDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWL  474

Query  473  NTTCPKCGAPAKRETDTMDTFTCSSWYYARYTDAHNDKMPFDPASANAWLGVDQYIGGIE  532
            + T    G  ++RET+TM   + SSWYY RY D+HN     D    + WL VD Y+GG E
Sbjct  475  EVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAE  533

Query  533  HACMHLLYSRFWYKFMRDIGLIKGDEPFNRLLTQGMVLANSYEAKSLKKFYTQEQMNNKE  592
            HA +HLLY+RFW K + D+G++   EPF++L+ QGM+L+ SY       + + +++++++
Sbjct  534  HAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSR-GALVATDKVEKRD  592

Query  593  ---YEKDGIKKEDIIVKMEKMSKSKANGVDPAEIIELFGADAVRIFVMFVAPPEKDKEWS  649
               ++ +    E++     KMSKS  N V+P +++E +GAD++R++ MF++P +    WS
Sbjct  593  GSFFHVE--TGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWS  650

Query  650  DEGVKGSARFLNRIWNLFLKYKDEEAFKNAKSFDYNNLSKDGQKLFRKYNktikkvtidi  709
            +EG+ GS +FL+R+  L+                 ++++ +    + K  +   K   + 
Sbjct  651  EEGLEGSRKFLDRVYRLITT---------------KEITEENSGALDKVYNETVKAVTEQ  695

Query  710  kdRFHFNTAIASLMELLNDMSTIKLANNDDYAMFREVIRGYLILLNPIAPHITEELYQIL  769
             D+  FNTAIA LM ++N       A N +  +F +  +G++ L+ P+APH+ EEL Q L
Sbjct  696  VDQMKFNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQAL  748

Query  770  NFGKMIIE-ESWVEHDEQYCKDDTFELVFQVNGKIRDRIEADVNISEDDAKNQALSSDKV  828
              +   I   +W   DE    ++  E+V Q++GK++ ++    ++S ++ ++ AL+++KV
Sbjct  749  TASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKV  808

Query  829  KQFTEGKNIVKVVYVKGKLVNIVVK  853
            +    GK+I+KV+ V  KLVNIV+K
Sbjct  809  QAEIAGKDIIKVIAVPNKLVNIVIK  833

952) leuS in NC_009832


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  553 bits (2089),  Expect = 1e-158, Method: Compositional matrix adjust.
 Identities = 367/867 (43%), Positives = 557/867 (65%), Gaps = 50/867 (5%)

Query  5    YRPEDIESNVQLHWQEKQTFKVTEDASKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIS  63
            Y    IE++ Q  W +++TFK   DASK K+Y L M+PYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIEYMKNQLKLLGFGYDWDR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NI   K Q++ LGF+YDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EIATCDPDYYRWEQWFFTKLYEKGLVYKKTSAVNWCPHDLTVLANEQVI-DGCCWRCDTK  182
            E+ T DP+YY+W QW+FTKLYEKGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITDYADQLLNDLDTLESWPEQVKTMQRNWIGRSEGVDITFDVAGSDEK  242
            V RK + QW +KIT YA++LL+DL+ ++ WPE +K MQRNWIG+S G ++TF V ++D  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGATYVAVAAGHPLAQQGAVNNPALAEFIEECRNTKVAEAEMA----TM  298
            +TV+TTRPDT+ GATY  +A+ H+L +  A+  +  AE + + +      +++A    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVD--AITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  299  EKKGMPTGLFAIHPLSGEQVPVWVANFVLMEYGTGAVMAVPAHDQRDWEFATKYGLPIKP  358
            EK G+ TG +AI+P++G ++PVW+A++VL  YGTGA+MAVPAHD+RDWEFA ++ L I P
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VVLALDGSQPDVQAEAMTEKGTLFNSGEFDGLDHQDGFNAIADKLVAKGVGQRKVNYRLR  418
            V   L+G+  +V+  A TE G  +NS+ +DGLD   ++  + + L A GVG+ +V YRLR
Sbjct  361  V---LEGG--NVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  419  DWGVSRQRYWGAPIPMVTLEDGTVMPTPEDQLPVILP--EDVVMDGIT-SPIKADPEWAK  475
            DW  SRQRYWG PIP++  EDGT  + PE +LP++LP   D+   G   SP+    +W  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  476  TT-VNGQPALRETDTFDTFMESSWYYARYTCPQYDKGMLDPAAANYWLPVDQYVGGIEHA  534
             T  +G  + RET+T      SSWYY RY  P+    + D    + WLPVD YVGG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  535  IMHLMYFRFFHKLLRDAGLVDSDEPAKRLLCQGMVLADAFYYSGNSGERVWVSPADAIVE  594
            ++HL+Y RF HK+L D G+V + EP ++L+ QGM+L+ +  Y ++ G  V   ++D +  
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS--YRDSRGALV---ATDKVEK  590

Query  595  RDDKGRIIKATDPQGRELVYAGMSKMSKSKNNGIDPQVMVEKYGADTVRLFMMFASPAEM  654
            RD  G ++     +  E    + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P + 
Sbjct  591  RD--GSFFHVETGEELE---QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  655  TLEWQESGVEGANRFLKRVWKLSYEHLEKGAVQPLNVATLTEDQK-ALRRDLHKTIAKVT  713
            ++ W E G+EG+ +FL RV +L            +    +TE++  AL +  + T+  VT
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRL------------ITTKEITEENSGALDKVYNETVKAVT  693

Query  714  DDIGRRQTFNTAIAAVMELMNKLARAPQESEQDRALLQEALLAVVRMLYPFTPHVCFSLW  773
            +++++ + FNTAIA +M ++N        ++++  L+ +   + V+++ PF+PH+   LW
Sbjct  694  EQVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELW  745

Query  774  QALGGEGD-VDTAAWPQADEQAMVEDSKLVVVQVNGKVRAKITVAADATEEQVRARAAEE  832
            QAL + G+ +   +WP  DE  +VE+   +VVQ++GKV+AK+ VA D + E+++  A  +
Sbjct  746  QALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALAN  805

Query  833  HLVAKYLDGVTVRKVIYVPGKLLNLVV  859
            + V   + G  + KVI VP KL+N+V+
Sbjct  806  EKVQAEIAGKDIIKVIAVPNKLVNIVI  832

953) Thein_1827 in NC_015681


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  553 bits (2089),  Expect = 1e-158, Method: Compositional matrix adjust.
 Identities = 363/868 (42%), Positives = 547/868 (64%), Gaps = 45/868 (5%)

Query  6    YDFANIETKWQKKWEESKAFAAIDGDKSRPKYYVLEMFPYPSGR-IHMGHVRNYAIGDVL  64
            YD + IE KWQ  W ++ +F + + D S+PK+Y L+MFPYPSG  +H+GH   Y+  D+L
Sbjct  4    YDHTAIEPKWQAFWADNHTFKT-GTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDIL  62

Query  65   ARYRKMRGANVLHPMGWDAFGLPAENAAIKHGTHPAKWTYENIAYMRNQLKRLGLSYDWN  124
            +R+++ +G NVLHPMGWDAFGLPAE+ A+  G +PA  T ENIA  + Q++ LG+SYDW+
Sbjct  63   SRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWD  122

Query  125  RELATCDPDYYRHEQRFFIEMLERGLAYRKKTTVNWCESCQTVLANEQV-EDGCCWRCGE  183
            RE+ T DP+YY+  Q++F  + E+GLAY     VNW E   T +ANE+V  DG   R G 
Sbjct  123  REVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGY  182

Query  184  EVVLKEMDGWFFRITAYAEELLQDIEKLRGKWPEKVLAMQINWIGKSEGAEIDFPIEGLD  243
             VV K M  W ++ITAYAE LL+D+E +   WPE +  MQ NWIGKS GA++ F + + D
Sbjct  183  PVVRKPMRQWMLKITAYAERLLEDLEEV--DWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  244  EKITVFTTRPDTLYGVTFMSLSPEHPLAKKLAEKDPelfskfeeflkeTRRERRQIEEGT  303
              +TVFTTRPDTL+G T+  L+PEH+L   ++  D              + +  + + + 
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  304  FEKKGLFLNAYAIHPLTGEKIPIFAANFVLMEYGTGAVMAVPAHDQRDFEFAQKYGLPIK  363
             EK G+   +YAI+P+ G  +P+  A++VL  YGTGA+MAVPAHD+RD EFA+++ L I 
Sbjct  301  -EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDII  359

Query  364  VVIQPEGEELSPENMKEAYEGPGIMVNSGPFSGLPNEEGKKKITAYLEENGLGRGKVTYR  423
             V++    E        A+   G+ +NS+ + GL +  +  K+   LE +G+G  +VTYR
Sbjct  360  PVLEGGNVE------EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYR  413

Query  424  LRDWGVSRQRYWGCPIPIIYCEHCGIVPEKIENLPVKLPLDAEL--DEHGRSPLPKLESF  481
            LRDW  SRQRYWG PIPII  E+    +    +LP+ LP+  ++     G SPL+++   
Sbjct  414  LRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDW  473

Query  482  VKTTCPKCGREARRETDTFDTFVESSWYFARFACPHSEEPL-DKEKVSYWLPVDQYIGGI  540
            +  T    G  +RRET+T      SSWY+ R+  PH+ E L D E +  WLPVD Y+GG 
Sbjct  474  LEVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGA  532

Query  541  EHAILHLLYARFFTKVLRDLGYLDFDEPFERLLTQGMVIKETYRCPKHGWLYPEEVSE-D  599
            EHA+LHLLYARF  KVL DLG +   EPF++L+ QGM++  +YR ++ + +  + V   D
Sbjct  533  EHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRD  592

Query  600  GRCLRDGCGEKVTIGRFEKMSKSKLNVVDPNAMIERYGADTVRLFMLFAAPPERDLEWSD  659
            G  ++   GE +  +   KMSKS  NVV+P+ ++E+YGADT+R++ +F +P +  + WS+
Sbjct  593  GSFFHVETGEELEQAP-AKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSE  651

Query  660  AGIEGAHRFLQRVFRLVTENLEELKKVKAYAGKQDDLPKTLRDLRHKTHQTIAKVTEDIE  719
             G+EG+++FL+RV+RL+T      K +     + + L K         ++T+  VTE+++
Sbjct  652  EGLEGSRKFLDRVYRLITT-----KEIT--EENSGALDKVY-------NETVKAVTEQVD  697

Query  720  KRYQFNTAIAAIMELVNTCYDTLGKDASQEALFWPVMREAVEAILLLLSPVAPHICEELW  779
            +  +FNTAIA +M +VN+          ++ LF     +   +++ L++P APH+ EELW
Sbjct  698  QM-KFNTAIAQLMVFVNAA-------NKEDKLF----SDYAKGFVQLIAPFAPHLGEELW  745

Query  780  EALGKDG-LIANAPWPEADKEALKAEEVTIAIQVNGKLRDQIQVPAGTSQEEIKEVALSR  838
            +AL   G  I+  PWP  D   L  ++V I +Q++GK++ ++ V+ + S+EE++EVAL+ 
Sbjct  746  QALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALAN  805

Query  839  PKVKRHVEGKEIRKVIFVPNKLINFVIK  866
             KV+ ++ GK+I KVI VPNKL+N+VIK
Sbjct  806  EKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

954) syl in NC_018607


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  553 bits (2089),  Expect = 1e-158, Method: Compositional matrix adjust.
 Identities = 350/865 (41%), Positives = 555/865 (65%), Gaps = 49/865 (5%)

Query  3    YNFTTIEKKWQKYWKDNQSFKTVSKPTDKKYYVLEMFPYPSGK-MHMGHVSNYTIADSIA  61
            Y+ T+IE KWQ +W DN++FKT + ++  K+Y L+MFPYPSG  +H+GH   YT +D ++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  62   RYYKLLGYDILHPMGWDAFGMPAENAAIDNKTHPAEWTLKNIANMKDQLNLLGYSYDWDR  121
            R+ +  G ++LHPMGWDAFG+PAE+ A+D   +PAE T  NIAN K Q+N LG+SYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  122  EVTTCLPDYYKWGQWFILKMYEKGLLYRKGGDVNWCDHCNTVLANEQVTAEGTCWRCDGE  181
            EV T  P+YYKW QW++ K+YEKGL Y     VNW ++  T +ANE+V ++GT  R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VTKKKLEQWYIKVTDYAEQLDADLKLLEGYWPDNVIAMQKNWIGRSVGAYINFNL-DDGK  240
            V +K + QW +K+T YAE+L  DL  ++  WP+++  MQ+NWIG+S GA + F++ D +K
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD--WPESIKDMQRNWIGKSTGANVTFKVKDTDK  241

Query  241  DFPIFTTRPDTIYGVTYMAIAWNYDGLLD-MCTPEQKSAVEEFIKKSAKIDQ--KTDYEK  297
            DF +FTTRPDT++G TY  +A   ++L+D + T++Q  AV ++ ++++   +  +TD  K
Sbjct  242  DFTVFTTRPDTLFGATYAVLA-PEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  298  E--GVFTGRYVVNPFNGEKAPLYAANFVLAEYGSGAVMAVPAHDQRDFEFAKKYNIPVKV  355
            E  GV TG Y +NP NG   P+  A++VLA YG+GA+MAVPAHD+RD EFAK++N+ +  
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  356  VIQNADNSIKAETMTEAYVEDGIVVNSDILNGLSSRDAIKRAIEYATEKGFGKEKVQYKL  415
            V++ ++          A+ EDG+ +NSD+L+GL    AI + +E     G G+E+V Y+L
Sbjct  361  VLEGGNVE------EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRL  414

Query  416  RDWLISRQRYWGNPLPFVHCEKCGVVPVPESELPITLPMDIEF---TVGENPLKKSASFV  472
            RDWL+SRQRYWG+P+P++H E     +VPESELP+ LP+  ++     GE+PL + +  +
Sbjct  415  RDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWL  474

Query  473  NTTCPKCGAPAKRETDTMDTFTCSSWYYARYTDAHNDKMPFDPASANAWLGVDQYIGGIE  532
            + T    G  ++RET+TM   + SSWYY RY D+HN     D    + WL VD Y+GG E
Sbjct  475  EVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAE  533

Query  533  HACMHLLYSRFWYKFMRDIGLIKGDEPFNRLLTQGMVLANSYEAKSLKKFYTQEQMNNKE  592
            HA +HLLY+RFW K + D+G++   EPF++L+ QGM+L+ SY       + + +++++++
Sbjct  534  HAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSR-GALVATDKVEKRD  592

Query  593  ---YEKDGIKKEDIIVKMEKMSKSKANGVDPAEIIELFGADAVRIFVMFVAPPEKDKEWS  649
               ++ +    E++     KMSKS  N V+P +++E +GAD++R++ MF++P +    WS
Sbjct  593  GSFFHVE--TGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWS  650

Query  650  DEGVKGSARFLNRIWNLFLKYKDEEAFKNAKSFDYNNLSKDGQKLFRKYNktikkvtidi  709
            +EG+ GS +FL+R+  L+                 ++++ +    + K  +   K   + 
Sbjct  651  EEGLEGSRKFLDRVYRLITT---------------KEITEENSGALDKVYNETVKAVTEQ  695

Query  710  kdRFHFNTAIASLMELLNDMSTIKLANNDDYAMFREVIRGYLILLNPIAPHITEELYQIL  769
             D+  FNTAIA LM ++N       A N +  +F +  +G++ L+ P+APH+ EEL Q L
Sbjct  696  VDQMKFNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQAL  748

Query  770  NFGKMIIE-ESWVEHDEQYCKDDTFELVFQVNGKIRERIEADVNISEDDAKNQALSSDKV  828
              +   I   +W   DE    ++  E+V Q++GK++ ++    ++S ++ ++ AL+++KV
Sbjct  749  TASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKV  808

Query  829  KQFTEGKNIVKVVYVKGKLVNIVVK  853
            +    GK+I+KV+ V  KLVNIV+K
Sbjct  809  QAEIAGKDIIKVIAVPNKLVNIVIK  833

955) Acear_0581 in NC_014378


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  553 bits (2088),  Expect = 2e-158, Method: Compositional matrix adjust.
 Identities = 373/844 (45%), Positives = 555/844 (66%), Gaps = 72/844 (8%)

Query  24   FETELDPDKPKHYTLEMFPYPSG-NLHMGHVRVYSIGDVIARFKRMQGYNVLHPMGWDSF  82
            F T  D+ KPK Y+L+MFPYPSG  LH+GH   Y+  D+++RFKR QG NVLHPMGWD+F
Sbjct  23   FKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSRFKRAQGHNVLHPMGWDAF  82

Query  83   GLPAENAAIERDIHPNSWTWDNIANMKKQLKSLGLSYDWNREVATCHPDYYKWTQWLFLQ  142
            GLPAE+ A++ + +P   T +NIAN K+Q+++LG+SYDW+REV T +P+YYKWTQW+F +
Sbjct  83   GLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTK  142

Query  143  LYKEDLAYKQESAVNWCPGCETVLANEQVV-NGGCERCDTEVEEKNLAQWFFKITEYAde  201
            LY  +LAY  E +VNW     T +ANE+V+ +G  ER +  V  K + QW +KIT YA E
Sbjct  143  LYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYA-E  201

Query  202  lledhellddWPDRVKTMQQNWIGRSEGVEIKFPIDGLDEELEVFTTRPDTVYGATYMVL  261
             L ++    DWP+ +K MQ+NWIG+S G ++ F + + D ++ VFTTRPDT++GATY VL
Sbjct  202  RLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVL  261

Query  262  APEHPLVeeltsgteqeeeVMDFVSEMKEKDDEERTSQESEKRGVFTGGYAVNPMTEERI  321
            APEH+LV +  + ++Q E V D+  +   K D  RT    EK GV TG+YA+NP+    +
Sbjct  262  APEHALV-DAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAINPVNGKEM  320

Query  322  PILVANYVLMSYGTGAIMAVPAHDQRDFDFAKKYDLDIRVVVQPEDEEMSGDTLEEAYTD  381
            P+ +A+YVL SYGTGAIMAVPAHD+RD +FAK+++LDI  V++      +G+  E A+T+
Sbjct  321  PVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE------GGNVEEAAFTE  374

Query  382  DGVIVNSGMLNGLDTDEAFDKIADYMEENNIGNKEINYRLRDWLVSRQRYWGTPIPIIYC  441
            DG+ +NS+ L+GLD   A+ K+ + +E + +GN ++ YRLRDWL SRQRYWG PIPII  
Sbjct  375  DGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHW  434

Query  442  DE--CGAvpvpeeelpvelpTDVEITGHGQSPLAQVDEFVNTTCPECGKAAQRETDTMDT  499
            ++    AVP +E  L + +  D+  +G G+SPLA+V + ++ T  +  K ++RET+TM  
Sbjct  435  EDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK-GRRETNTMPQ  493

Query  500  FVDSSWYFLRYTDSGNEEEIFDSKKANYWMNVDQYVGGIEHAILHLLYARFFMKFISDLG  559
              +SSWY+LRY D+ N E + D    + W+ VD YVGG EHA+LHLLYARF  K + DLG
Sbjct  494  WAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLG  553

Query  560  IADAKEPFERLLAQGMVL-------------------KDG---------------AKMSK  585
            +  +KEPF++L+ QGM+L                   +DG               AKMSK
Sbjct  554  VVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSK  613

Query  586  SKGNVVDPLEIIDNYGADTARLFMLFAAPPQKDLEWDDEGVKGASRFLDRVWRVTAEYTD  645
            S  NVV+P +++++YGADT R++ +F +P +  + W +EG+ G+ +FLDRV R+ +  T 
Sbjct  614  SLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLIT--TK  671

Query  646  QIKEidldnlqidnldKSEKELYRSVHLAIKDVTEDLDNRKQFNTAISSIMELINSLYQY  705
            +I E             +   L +  + ++K VTE++D+ K FNTAI+ +M ++N+    
Sbjct  672  EITE------------ENSGALDKVYNETVKAVTEQVDQMK-FNTAIAQLMVFVNA----  714

Query  706  RDQaaeenielialaVKTAILLLSPFAPHITEELWSKL-GQSESVHCQEWPEYKEEALKK  764
                A+ +  L++   K  + L++PFAPH+ EELW  L + +ES+    WP Y E  L  
Sbjct  715  ----ANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVE  770

Query  765  DEITIVVQINGNVRDRVEVAPNIEEEELKELVLAQDKVQDYLTEDKELVKTIVVPKKLVN  824
            +++ IVVQI+G+V+ ++ VA ++  EEL+E+ LA++KVQ  ++ +K+++K I VP+KLVN
Sbjct  771  NDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIA-GKDIIKVIAVPNKLVN  829

Query  825  LVIQ  828
            +VI+
Sbjct  830  IVIK  833

956) leuS in NC_011146


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  553 bits (2086),  Expect = 2e-158, Method: Compositional matrix adjust.
 Identities = 369/858 (44%), Positives = 548/858 (64%), Gaps = 68/858 (7%)

Query  5    YVPSAVEEKWQGYWAEHKSFKANEDPSRKKYYLLEMFPYPSGK-IHMGHVRNYSIGDVIA  63
            Y  +A+E KWQ++WA++ +FK+  D+S+ K+Y L+MFPYPSG  +H+GH   Y+  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RFKRMQGYNVLHPMGWDAFGMPAENAAIQHKSHPAKWTYENIAYMRGQLKTLGLSYDWDR  123
            RFKR QG NVLHPMGWDAFG+PAE+ A++  ++PA  T ENIA  + Q+++LG+SYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCDLDYYKWEQRIFLEMYKKGLAYKKSSAVNWCPKCETVLANEQV-EDGCCWRCDSP  182
            E+ T D +YYKW Q+IF  +Y KGLAY    +VNW     T +ANE+V  DG   R + P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VQQKELEQWSFRITNYAQELLDDTYKLTGWPERVLTMQRNWIGRSTGCEIDFPLESGLGK  242
            V +K + QW ++IT YA+ LL+D     +WPE +  MQRNWIG+STG ++ F +      
Sbjct  184  VVRKPMRQWMLKITAYAERLLED-LEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  IKVFTTRQDTLFGATFMSLAAEHPMALDLAGDAQKAEVAAFIDKVKKTDRIKRGAEDLEK  302
            + VFTTR DTLFGAT+  LA+EH++   ++   Q   VA +  +      + R     EK
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEK  302

Query  303  EGVFTGSYCINPVTNTKMPIYLANFVLMDYGTGAVMAVPTHDQRDFEFAKKYNLPLKVVI  362
             GV TGSY INPV    MP+ +A++VL  YGTGA+MAVP+HD+RD EFAK++NL +  V+
Sbjct  303  TGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL  362

Query  363  QPEGETLDPATMTEAYTAEGIMVNSGRFDGMGNADAKEAIADFLEKEGIGKKTVNFRLRD  422
              EG  ++ A    A+T +G+ +NS+ +DG+++A A   + + LE EG+G+  V +RLRD
Sbjct  363  --EGGNVEEA----AFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  423  WGISRQRYWGNPIPVINCDLCGVVAVPEADLPVVLPMDAEF--TGEGGNPLARVDSFTTC  480
            W +SRQRYWG+PIP+I+ +     AVPE++LP+VLP+  ++  +G G +PLA V      
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  481  TCPQCGETARRETDTMDTFVQSSWYFLRYCSPKFSAGPLDREKVEAWMPVDQYIGGIEHA  540
            T  + G  +RRET+TM     SSWY+LRY  P  +    D E +  W+PVD Y+GG EHA
Sbjct  477  TRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  541  VLHLLYARFFTKVLRDLGYCNVDEPFSNLLTQGMVI-------------------KDG--  579
            VLHLLYARF  KVL DLG     EPF +L+ QGM++                   +DG  
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSF  595

Query  580  -------------AKMSKSKGNVVDPNALIERYGADTARLFSLFAAPPEKDLDWSDQGVD  626
                         AKMSKS  NVV+P+ ++E+YGADT R++ +F +P +  + WS++G++
Sbjct  596  FHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLE  655

Query  627  GSYRFLNRVWRLVYDVLPVIGDAGAVNPGELGAEAKKLRRAVHKTIKKVSEDVEERFHFN  686
            GS +FL+RV RL+        +    N+G L+       +  + T+K V+E+V++   FN
Sbjct  656  GSRKFLDRVYRLI-----TTKEITEENSGALD-------KVYNETVKAVTEQVDQ-MKFN  702

Query  687  TAIAAVMELVNAIQAFSAKDAPENvavvreavesvvrllAPFVPNFAEELWFQL-GHASV  745
            TAIA +M +VNA        A  +  +  +   + V+L+APF P+++EELW  L + +  
Sbjct  703  TAIAQLMVFVNA--------ANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGES  754

Query  746  LEAAGWPGYdaaavvdeevtvvIQVNGKLRSKLTVAPDAKEEEVRAQALADDKIKPYLEG  805
            +    WP+YD + +V+++V +V+Q++GK+++KL VA D   EE++  ALA++K+++ + G
Sbjct  755  ISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAG  814

Query  806  KDVKKVVYVPGKLVSIVV  823
            KD+ KV+ VP KLV+IV+
Sbjct  815  KDIIKVIAVPNKLVNIVI  832

957) leuS in NC_012806


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  553 bits (2088),  Expect = 2e-158, Method: Compositional matrix adjust.
 Identities = 364/845 (44%), Positives = 545/845 (65%), Gaps = 71/845 (8%)

Query  2    FKHQEIDKKWQKHWEFNKVFKTQDKSLK-KFYALDMFPYPSAAGLHLGHPLGYTATDIIS  60
            + H  I+ KWQ  W  N  FKT   + K KFYALDMFPYPS+AGLH+GHP GYTATDI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  61   RLKRLQGYDVLHPMGWDAFGLPAEQYAIKTGNHPADFTAKNIENFRRQIKAFGFSYDWEK  120
            R+KR QG +VLHPMGWDAFGLPAEQYA+ TGN+PA+FTA NI NF+RQI+A+GFSYDW++
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  121  EIDTTDPAFYYHTQWIFKLLYKQNLAEIRETDVNWCQDLGTVLANEEIVQDENGNLVSER  180
            E++TTDP +Y  TQWIF  LY + LA   E  VNW ++LGT +ANEE++ D      SER
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGT----SER  179

Query  181  GGFPVTNKKMKQWVLKITNYADKLLEGLKDVDFPDSLKLLQEKWIGKSKGWEVKFFLEDQ  240
            GG+PV  K M+QW+LKIT YA++LLE+L +VD P+S+K +Q +WIGKS G +V F + D 
Sbjct  180  GGYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDT  239

Query  241  EDYIEVYTTRIETIFGVSFVAISTNHQLSSKLAS--QNPEIQKFIDQNFSTSNKLQTN--  296
            +  + V+TTR +T+FG ++  ++ +H L   +++  Q   +  +  Q    S+  +T+  
Sbjct  240  DKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA  299

Query  297  -KKTGIFTNLYLTHPILKTKIPVFISNYVLNNYGTGAIMGVPAHDSRDLDFAQVMDLKVV  355
              KTG+ T  Y  +P+    +PV I++YVL +YGTGAIM+VPAHD RD +FA+  +L ++
Sbjct  300  KEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDII  359

Query  356  KVID----------DQNLLINSDKYNGLTILQAREKIFLDLSTQNLINQKTSYKIKDWVF  405
             V++          ++ L INSD  +GL    A  K+   L ++ + N++ +Y+++DW+F
Sbjct  360  PVLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLF  419

Query  406  SRQRYWGEPFP-VYFDENDNIFLEEKIVE--LPYMDKIKPNGDGQSPLASNKKWLTFSK-  461
            SRQRYWGEP+P +  ++  +  + E  +   LP    I+P+G G+SPLA+   WL  ++ 
Sbjct  420  SRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRE  479

Query  462  DGQKYRRETNTMPQWAGSSWYYLAYILKNSDGSYLNLDSPQALERFKKWLPVDLYIGGQE  521
            DG K RRETNTMPQWAGSSWYYL YI  ++     +L   + L   K+WLPVD+Y+GG E
Sbjct  480  DGVKGRRETNTMPQWAGSSWYYLRYIDPHNTE---KLADEELL---KQWLPVDIYVGGAE  533

Query  522  HAVGHLIYSRFWHKVLYEAGIVNTHEPFFKIVNQGMLLgsd-------------------  562
            HAV HL+Y+RFWHKVLY+ G+V T EPF K+ NQGM+LG+                    
Sbjct  534  HAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDG  593

Query  563  --------------gskmskskgNVINPDEILELYGADALRLFLMFMSPLTDVKNWKNSG  608
                           +KMSKS  NV+NPD+++E YGAD+LR++ MFM+PL     W + G
Sbjct  594  SFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEG  653

Query  609  IKSMYQWLERVYRVITTSYQYDAKLLKNITFEQTYHKFIAETTQSIEDLKFNVAISKLMV  668
            + +  + L+RVYR+ITT    +    ++ ++++ Y+  +   T+ ++++KFN AI++LMV
Sbjct  654  LEGSRKFLDRVYRLITTK---EITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMV  710

Query  669  YINFLSKQSVLPDKKYLTSFIIIFSTFAPHlae---ellekldendlFNQKWPEFDKKKT  725
            ++N  +K+  L    Y  +F+ +++ FAPHL+E   + L   +E+  +   WP +D  K 
Sbjct  711  FVNAANKEDKLF-SDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVP-WPSYDESKL  768

Query  726  IDLDYNLPISINGKTRTVINLKNKTTEEEIIKIAKNNPALSKYLENAEIIKTIYVAKKML  785
            ++ D ++ + I+GK ++ + + +  + EE+  +A  N  +   +   +IIK I V++K++
Sbjct  769  VENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLV  828

Query  786  NFITK  790
            N++ K
Sbjct  829  NIVIK  833

958) Dde_2439 in NC_007519


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  553 bits (2086),  Expect = 2e-158, Method: Compositional matrix adjust.
 Identities = 356/864 (42%), Positives = 540/864 (63%), Gaps = 75/864 (8%)

Query  3    YNPQAIEEKWQHIWEEKEMFRSEHGSDKPKYYVLEMFPYPSG-NIHMGHVRNYSIGDVVA  61
            Y+  AIE KWQ +W +++ F++  ++ KPK+Y L+MFPYPSG  +H+GH   Y+  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  62   RFKRMQGFNVLHPMGWDAFGLPAENAAIKHDTHPAKWTYSNIDNMRSQLKRLGYSYDWRR  121
            RFKR QG NVLHPMGWDAFGLPAE+ A+  + +PA  T  NI N + Q++ LG+SYDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  122  ELATCDAEYYRWEQLFFLKFMEKGLIYRKKAPQNWCPKCNTVLANEQVI-DGLCWRCDSV  180
            E+ T D++YY+W Q +F K+ EKGL Y    P NW     T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  181  VEQRDLAQWFLRITSYAEELLADLEKLTGGWPDRVLTMQHNWIGKSVGAEIEFAVDGSDE  240
            V ++ + QW L+IT+YAE LL DLE +  +WP+ +  MQ+NWIGKS GA++ F V ++D 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV--DWPESIKDMQRNWIGKSTGANVTFKVKDTDK  241

Query  241  TVKVFTTRPDTVFGSTFMSIAPEHPLVEKLITGTGQEETVRAFVTRIRNMDRIERTADTL  300
               VFTTRPDT+FG+T+  +APEH+LV+  IT ++Q E+V  +  +      + RT  + 
Sbjct  242  DFTVFTTRPDTLFGATYAVLAPEHALVDA-ITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  301  EKEGVFTGAYCINPLSGRRMPIYVANFVLAEYGTGAVMAVPAHDERDFEFARKYDLPMEV  360
            EK GV TG+Y INP++G+ MP+ +A++VLA YGTGA+MAVPAHDERD EFA++++L +  
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  361  VIQPEGAELTPATMETAYTGQGTMVGSGQFSGLPNEEGKTKIAEWLEANGKGKRTVNYRL  420
            V++    E      E+A+T +G  + S+ + GL +  + +K+ EWLEA+G G+  V YRL
Sbjct  361  VLEGGNVE------EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRL  414

Query  421  RDWNISRQRYWGAPIPVVYCEKCGIVPEKAENLPVRLPL--DIKTRSDGRSPLGETPEFY  478
            RDW +SRQRYWG PIP++  E     +    +LP+ LP+  DI+  + G SPL++  +  
Sbjct  415  RDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWL  474

Query  479  ECRCPACGEKARRETDTMDTFVESSWYFARYTSAGDNEAPFDAQALKYWLPVDQYIGGVE  538
            E      G K+RRET+TM     SSWY+ RY  + + E   D + LK WLPVD Y+GG E
Sbjct  475  EV-TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAE  533

Query  539  HAILHLLYARFFIKALRDCGYMDLDEPFANLLTQGMVL----------------------  576
            HA+LHLLYARF  K L D G +   EPF +L+ QGM+L                      
Sbjct  534  HAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDG  593

Query  577  ------------MDGAKMSKSKGNVVDPTEMISRYGADTVRLFCLFAAPPERDFDWSDSG  624
                           AKMSKS  NVV+P +++ +YGADT+R++ +F +P +  + WS+ G
Sbjct  594  SFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEG  653

Query  625  IEGASRFVNRVWRLVEDLPAGMAPMAPCSSSSDDCTGAAAKDIRQKEHATVKKAGADIQN  684
            +EG+ +F++RV RL+                +++ +GA  K   +    TVK    ++ +
Sbjct  654  LEGSRKFLDRVYRLI-----------TTKEITEENSGALDKVYNE----TVKAVTEQV-D  697

Query  685  RFQFNTAISAVMELVNALYLTRDELGADEKGRRVLGSAVSSVLAMLAPITPHLCEELWEQ  744
            + +FNTAI+ +M +VN          A +K  ++++    + + ++AP++PHL EELW+ 
Sbjct  698  QMKFNTAIAQLMVFVN----------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  745  L-GHKDMLTARPWPRYDEDALLRDEVVIPVSVNGKLRSKMTVPAGTGkeeleklalaeaN  803
            L +  + ++  PWP YDE  L+ ++V I V ++GK+++K+ V+ + ++EEL+ +ALA+ +
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  804  VVRHTEGLTVRKVIVIPGKMVNVV  827
            V  +  G  + KVI +P K+VN+V
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIV  831

959) BPP43_00555 in NC_019908


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  553 bits (2087),  Expect = 2e-158, Method: Compositional matrix adjust.
 Identities = 352/865 (41%), Positives = 555/865 (65%), Gaps = 49/865 (5%)

Query  3    YNFTTIEKKWQKYWKDNQSFKTVSKPTDKKYYVLEMFPYPSGK-MHMGHVSNYTIADSIA  61
            Y+ T+IE KWQ +W DN++FKT + ++  K+Y L+MFPYPSG  +H+GH   YT +D ++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  62   RYYKLLGYDILHPMGWDAFGMPAENAAIDNKTHPAEWTLKNIANMKDQLNLLGYSYDWDR  121
            R+ +  G ++LHPMGWDAFG+PAE+ A+D   +PAE T  NIAN K Q+N LG+SYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  122  EVTTCLPDYYKWGQWFILKMYEKGLLYRKGGDVNWCDHCNTVLANEQVTAEGTCWRCDGE  181
            EV T  P+YYKW QW++ K+YEKGL Y     VNW ++  T +ANE+V ++GT  R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VTKKKLEQWYIKVTDYAEQLDADLKLLEGYWPDNVIAMQKNWIGRSVGAYINFNL-DDGK  240
            V +K + QW +K+T YAE+L  DL  ++  WP+++  MQ+NWIG+S GA + F++ D +K
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD--WPESIKDMQRNWIGKSTGANVTFKVKDTDK  241

Query  241  DFPIFTTRPDTIYGVTYMAIAWNYDGLLD-MCTPEQKSAVEEFIKKSA-KID-QKTDYEK  297
            DF +FTTRPDT++G TY  +A   ++L+D + T++Q  AV ++ ++++ K D  +TD  K
Sbjct  242  DFTVFTTRPDTLFGATYAVLA-PEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  298  E--GVFTGRYVVNPFNGEKAPLYAANFVLAEYGSGAVMAVPAHDQRDFEFAKKYNIPVKV  355
            E  GV TG Y +NP NG   P+  A++VLA YG+GA+MAVPAHD+RD EFAK++N+ +  
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  356  VIQNADNSIKAETMTEAYVEDGIVVNSDILNGLSSRDAIKRAIEYATEKGFGKEKVQYKL  415
            V++ ++          A+ EDG+ +NSD+L+GL    AI + +E     G G+E+V Y+L
Sbjct  361  VLEGGNVE------EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRL  414

Query  416  RDWLISRQRYWGNPLPFVHCEKCGVVPVPESELPITLPMDIEF---TVGENPLKKSASFV  472
            RDWL+SRQRYWG+P+P++H E     +VPESELP+ LP+  ++     GE+PL + +  +
Sbjct  415  RDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWL  474

Query  473  NTTCPKCGAPAKRETDTMDTFTCSSWYYARYTDAHNDKMPFDPASANAWLGVDQYIGGIE  532
            + T    G  ++RET+TM   + SSWYY RY D+HN     D    + WL VD Y+GG E
Sbjct  475  EVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAE  533

Query  533  HACMHLLYSRFWYKFMRDIGLIKGDEPFNRLLTQGMVLANSYEAKSLKKFYTQEQMNNKE  592
            HA +HLLY+RFW K + D+G++   EPF++L+ QGM+L+ SY       + + +++++++
Sbjct  534  HAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSR-GALVATDKVEKRD  592

Query  593  ---YEKDGIKKEDIIVKMEKMSKSKANGVDPAEIIELFGADAVRIFVMFVAPPEKDKEWS  649
               ++ +    E++     KMSKS  N V+P +++E +GAD++R++ MF++P +    WS
Sbjct  593  GSFFHVE--TGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWS  650

Query  650  DEGVKGSARFLNRIWNLFLKYKDEEAFKNAKSFDYNNLSKDGQKLFRKYNktikkvtidi  709
            +EG+ GS +FL+R+  L+                 ++++ +    + K  +   K   + 
Sbjct  651  EEGLEGSRKFLDRVYRLITT---------------KEITEENSGALDKVYNETVKAVTEQ  695

Query  710  kdRFHFNTAIASLMELLNDMSTIKLANNDDYAMFREVIRGYLILLNPIAPHITEELYQIL  769
             D+  FNTAIA LM ++N       A N +  +F +  +G++ L+ P+APH+ EEL Q L
Sbjct  696  VDQMKFNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQAL  748

Query  770  NFGKMIIE-ERWVEHDEQYCKDDTFELVFQVNGKIRDRIEADVNISEDDAKNQALSSDKV  828
              +   I    W   DE    ++  E+V Q++GK++ ++    ++S ++ ++ AL+++KV
Sbjct  749  TASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKV  808

Query  829  KQFTEGKNIVKVVYVKGKLVNIVVK  853
            +    GK+I+KV+ V  KLVNIV+K
Sbjct  809  QAEIAGKDIIKVIAVPNKLVNIVIK  833

960) leuS in NC_020561


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  553 bits (2088),  Expect = 2e-158, Method: Compositional matrix adjust.
 Identities = 344/843 (41%), Positives = 542/843 (65%), Gaps = 24/843 (2%)

Query  5    FNPQAADKRWQAAWDEGQTFRADDASPKPKSYVLEMFPYPSGR-IHMGHVRNYTMGDVLA  63
            ++  A + +WQA W + +TF+++  ++KPK Y L+MFPYPSG  +H+GH   YT  D+L+
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RFRRMTGHEVLHPMGWDAFGMPAENAAMEKKVHPGSWTRENIAAMKAQLKRLGFALDWSR  123
            RF+R  GH+VLHPMGWDAFG+PAE+ AM+   +P+  T ENIA  K Q++ LGF+ DW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCEPDYYGQEQALFLDLYAAGLVYRKESAVNW-DPVDMTVLANEQVIDGRGWRSGAL  182
            E+ T +P+YY   Q +F  LY  GL Y  E +VNW + ++ ++  +E + DG + R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERRKLSQWFLKITDFADELLEGLSTLDQWPEKVRLMQENWIGKSQGLRFTFKLDAPAAG  242
            V R+ + QW LKIT +A+ LLE+L  +D WPE ++ MQ NWIGKS G   TFK+      
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDT---  239

Query  243  HDGFDVFTTRPDTMFGASFAAISVDHPI--ALALAEQDARLAAFSEECRRtgtaaaeiet  300
            + +F VFTTRPDT+FGA++A ++ +H++  A++ ++Q   +A +  +    +  A    +
Sbjct  240  DKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA  299

Query  301  aeKLGYDTGLSVIHPLDPTWKLPLFVANFVLMDYGTGAVFGCPAHDQRDLDFARKYALPV  360
             EK G  TG   I+P++    +P+ +A++VL  YGTGA+ + PAHD+RD +FA+++ L +
Sbjct  300  KEKTGVWTGSYAINPVNGK-EMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDI  358

Query  361  ERVVAPSPEEADAPIGDEAYTGPGRLVNSRFLDGMSVEGAKAAVIARAEGEGWGRGTTVW  420
              V+       ++ + + A+T  G  +NS FLDG+   +A A ++ + E+EG G      
Sbjct  359  IPVL------EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTY  412

Query  421  RLRDWGVSRQRYWGTPIPIIHCDACGPVAVPKDQLPVVLPEDVSFDVPG---NPLDRHPT  477
            RLRDW  SRQRYWG PIPIIH +   + AVP  +LP+VLP    +  +G   +PL     
Sbjct  413  RLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTD  472

Query  478  WKNVDCPSCGAPARRETDTLDTFVDSSWYFIRFASAPK-DRPFDRAVAEQWLPVGQYIGG  536
            W +V     G  +RRET+T+    +SSWY++R+  + + ++  D  +  QWLPV+ Y+GG
Sbjct  473  WLEVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGG  531

Query  537  VEHAILHLLYSRFWTRALKRIGRIDIAEPFTGLFTQGMVTHETYKAPDGRWLSPEEVENR  596
             EHA+LHLLY+RFW + L  +G +   EPF  LF QGM+   +Y+ + G  ++ + VE+R
Sbjct  532  AEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKR  591

Query  597  DGGLVIVETGEAVTPGRVEKMSKSKKNVVDPGPIVDQYGADAVRWFMLSDSPPERDLAWS  656
            DG++  VETGE +  +   KMSKS KNVV+P+ +V+QYGAD++R + +  +P +  +AWS
Sbjct  592  DGSFFHVETGEELEQAP-AKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWS  650

Query  657  EAGIEGAWRFVQRLWRLAGSIAGAEGEDRDLDRKLHRTIAGVAEDVEALSFNKAVAKLYE  716
            E G+EG+++F++R+ RL  +   +E +   LD+  + T+ +V+E+V+ + FN A+A+L  
Sbjct  651  EEGLEGSRKFLDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMV  710

Query  717  LANAIEKAQPSASRDFAVRTIVRLVAPMVPHLAEEAWSLLGETG-LVADAPWPEADPALL  775
            + NA +K +     D+A + +V+L+AP  PHL+EE W  L  +G  ++  PWP  D + L
Sbjct  711  FVNAANKED-KLFSDYA-KGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKL  768

Query  776  VDDEVTIAIQINGKLRDTLVAPKGTDRPALEALALGSDKVIRLLEGKTPKKVIVVPDRLV  835
            V+++V I +QI+GK++  LV +K+  R  L+ +AL+++KV   + GK   KVI VP++LV
Sbjct  769  VENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLV  828

Query  836  NLV  838
            N+V
Sbjct  829  NIV  831

961) LeuS in NC_020519


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  552 bits (2085),  Expect = 3e-158, Method: Compositional matrix adjust.
 Identities = 356/739 (49%), Positives = 505/739 (69%), Gaps = 59/739 (7%)

Query  220  LVYRSNSTVNWCPGLGTVLANEEVTADGRSERGNFPVFRKNLSQWMMRITAYSDRLIDDL  279
            L Y ++  VNW   LGT +ANEEV +DG SERG +PV RK + QWM++ITAY++RL++DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  280  ELLDWTEKVKSMQRNWIGRSRGAEVDFSAE--GETVTVFTTRPDTLFGATYMVLAPEHEL  337
            E +DW E +K MQRNWIG+S GA+V F     +   TVFTTRPDTLFGATY VLAPEH L
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  338  VDVLLEKAGSYEGVDARWTNGQASPAEAVAAYRASIAAKSDLERQE-NKEKTGVFLGVYA  396
            VD +                  +  AEAVA Y+   + KSDL R +  KEKTGV  G YA
Sbjct  268  VDAI----------------TTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYA  311

Query  397  TNPVNGDQITVFIADYVLTGYGTGAIMAVPAHDERDYEFATVLGLPIKEVVAGGNIEEAA  456
             NPVNG ++ V IADYVL++YGTGAIMAVPAHDERD EFA  + L I  V+ GGN+EEAA
Sbjct  312  INPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEAA  371

Query  457  FTESGEAVNSANDNGLDINGLAKDEAIAKTIEWLEEKELGRGTIQYKLRDWLFARQRYWG  516
            FTE G  +NS       ++GL K  AIAK +EWLE   +G   + Y+LRDWLF+RQRYWG
Sbjct  372  FTEDGLHINSDF-----LDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWG  426

Query  517  EPFPIVYDENGQAHALPDSMLPVELPEVEDYKPVSFDPEDADSELSPPLAKAREWVEVEL  576
            EP+PI+  E+G + A+P+S LP+ LP   D +P + +         +PLA+  +W+EV  
Sbjct  427  EPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTG--------ESPLANVTDWLEVTR  478

Query  577  DLGDGKKKYTRDTNVMPQWAGSSWYQLRYVDPSNDEQFCNIENERYWTGPRPETHGPNDP  636
            +  DG K   R+TN MPQWAGSSWY LRY+DP N E++ + E  + W             
Sbjct  479  E--DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWL------------  523

Query  637  GGVDLYVGGVEHAVLHLLYARFWHKVLFDLGHVSSKEPYRRLYNQGYIQAFAYTDSRGVY  696
              VD+YVGG EHAVLHLLYARFWHKVL+DLG V++KEP+++L+NQG I + +Y DSRG  
Sbjct  524  -PVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGAL  582

Query  697  VPADDVEEKDGKFFY--QGEEVNQEYGKMGKSLKNAVAPDDICNNFGADTLRVYEMAMGP  754
            V++D VE +DG FF    GEE++Q  +KM+KSLKN V PDD+ +++GADTLRVYEM MGP
Sbjct  583  VATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGP  642

Query  755  LDTSRPWATKDVVGAQRFLQRLWRLVVDENTGEVLTRDEVLTDDDNKQLHRTIAGVRDDY  814
            LD+S +W+  ++ G+++FL+R+ RL+   +  E       L    +K  + T+ +V ++ 
Sbjct  643  LDASIAWSEEGLEGSRKFLDRVYRLITTKEITE--ENSGAL----DKVYNETVKAVTEQV  696

Query  815  TNLRVNTVVAKLIEYVNYLTKTYPDTIPAGAVLPLIVMVSPIAPHIAEELWKKL-GHDDT  873
             +++ NT +A+L+ +VN   K   D + ++    ++ +++P+APH++EELW+ L + +++
Sbjct  697  DQMKFNTAIAQLMVFVNAANKE--DKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGES  754

Query  874  VTYEPFPTFEEKWLTDDEIELPVQVNGKVRGRITVAADASQEQVIEAALADEKVQEQISG  933
            ++Y P P+++E  L ++++E+ VQ++GKV++++ VA D S+E++ E ALA+EKVQ +I+G
Sbjct  755  ISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAG  814

Query  934  KNLIKQIVVSGRMVNLVVK  952
            K++IK I V+ ++VN+V+K
Sbjct  815  KDIIKVIAVPNKLVNIVIK  833


 Score =  141 bits (519),  Expect = 2e-34, Method: Compositional matrix adjust.
 Identities = 79/149 (54%), Positives = 104/149 (70%), Gaps = 11/149 (7%)

Query  23   IEGEWQNYWTDNGTFNAPNPVGDLAPADGKALPEDKLFVQDMFPYPSGAGLHVGHPLGYI  82
            IE  WQ +W+DN TF++           G   +  K++  DMFPYPSGAGLHVGHP GY 
Sbjct  9    IEPKWQAFWADNHTFKT-----------GTDASKPKFYALDMFPYPSGAGLHVGHPEGYT  57

Query  83   ATDVFARYNRMLGKNVLHTLGYDAFGLPAEQYAIQTGTHPRTTTMANIENMKRQLGALGL  142
            ATD+++R++R  G NVLH +G DAFGLPAEQYA++TG +P   T  NI N KRQ+ ALG+
Sbjct  58   ATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGF  117

Query  143  GHDSRRAVATTDPEFYKWTQWIFLQIFNS  171
            + D  R V TTDP++YKWTQWIF ++++ 
Sbjct  118  SYDWDREVNTTDPNYYKWTQWIFTKLYEK  146

962) leuS in NC_017079


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  552 bits (2085),  Expect = 3e-158, Method: Compositional matrix adjust.
 Identities = 372/864 (44%), Positives = 549/864 (64%), Gaps = 73/864 (8%)

Query  5    YNPAEIEPKWQQIWEEQQLYKTVEDPERPKWYALTMLPYPSG-DLHTGHWYAYTPSDAAA  63
            Y+ + IEPKWQ +W +++ +KT  D+ +PK YAL M+PYPSG +LH GH  +YT++D  +
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYRRMNGYNVFFPIGFDAFGLPAENAAIKHGVHPAKWTYANIERMRKQLRRMGAMWAWDR  123
            R++R +G NV+ P+G DAFGLPAE+ A+  G +PA  T  NI   ++Q+  +G    WDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EAITCDPEYYKWTQWFFRKFYDAGIAYREYAPVDFCPTCNTTLAREQVWGEDRHCERCGT  183
            E  T DP+YYKWTQW+F K+Y+ G+AY    PV+      T++A E+V  ++   ER G 
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGT-SERGGY  182

Query  184  PVIKKNLEQWKFRITRYADELIDMLDQIDWPERVKVMQRNWIGRSYGAEVIFRTEQGE-P  242
            PV++K + QW ++IT YA+ L++ L+++DWPE +K MQRNWIG+S GA+V F+  + +  
Sbjct  183  PVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LEIFTTRPDTLWGATFMVLAPEHPLVDAVTTDEHRAEVEAYKAQAARMDEIQRTAADKEK  302
            + +FTTRPDTL GAT+ VLAPEH+LVDA+TT ++   V  YK QA+   ++ RT   KEK
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEK  302

Query  303  TGVFTGGYAINPVNGERIPIWIADYVMMGYGTGAIMAVPAHDARDFEFAKKYGLEIRRVI  362
            TGV TG+YAINPVNG  +P+WIADYV+ +YGTGAIMAVPAHD RD EFAK++ L+I  V+
Sbjct  303  TGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL  362

Query  363  TGPDGATGPLEEAYDSKEEGEMINSGPFDGTPVKGAVEKVTEWLEANGIGRRAVNYRLRD  422
             G +   +++       E+G  INS+ +DG    +A+ K+ EWLEA+G+G   V YRLRD
Sbjct  363  EGGNVEEAAF------TEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  423  WLISRQRMWGAPIPIIYCPNCGTVPVPYEDLPVLLPEDAEFKP--TGESPLKYHEGFRRV  480
            WL+SRQR WG PIPII   +  + +VP  +LP++LP   +++P  TGESPL    +   V
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  481  KCPECGGEAERETDTMDTFMCSSWYQYAYISPYWKKGERLSPDDLPWDKAKGDYWLPVDQ  540
               E G  + RET+TM     SSWY   YI P   + E+L+ ++L  +      WLPVD 
Sbjct  477  -TREDGVKGRRETNTMPQWAGSSWYYLRYIDP--HNTEKLADEELLKQ------WLPVDI  527

Query  541  YTGGIEHATMHLLYTRFFTKAMRDLGLVNFDEPMLRLFNQGMILGPD-------------  587
            Y GG EHA +HLLY+RF  K + DLG+V   EP  +LFNQGMILG               
Sbjct  528  YVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDK  587

Query  588  --------------------GEKMSKSRGNVINPDEVVDRYGADTVRGYLMFIGPWDQGG  627
                                  KMSKS  NV+NPD+VV++YGADT+R Y MF+GP D + 
Sbjct  588  VEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASI  647

Query  628  PWDPQAIEGVHRFLHRVWAVVTEDVQLDRPLLDADQAPDPAQERALERKLHQTILKVTDD  687
            +W  +++EG ++FL+RV  ++T      + + + + +       AL++  ++T+  VT++
Sbjct  648  AWSEEGLEGSRKFLDRVYRLIT-----TKEITEENSG-------ALDKVYNETVKAVTEQ  695

Query  688  IEHFRFNTAIAALMELNNYLLRARETSVVNSPIWNQAIRTLILMMAPFFPHIAEELWHR-  746
            +++ +FNTAIA LM + N       ++  +  + ++  + ++ ++APF PH++EELW+  
Sbjct  696  VDQMKFNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQAL  748

Query  747  QGNTSSVHLQRWPVGDPEKAREEEITVVVQVNGKVRDKLLVPPGTPADELERSALQLSGV  806
             ++  S+    WP  D  K  E+++ +VVQ++GKV+ KL+V+ + + +EL+  AL    V
Sbjct  749  TASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKV  808

Query  807  VKWLNGQTPRKVVVVPDKLVNIVI  830
               + G+   KV+ VP+KLVNIVI
Sbjct  809  QAEIAGKDIIKVIAVPNKLVNIVI  832

963) leuS in NC_011852


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  552 bits (2084),  Expect = 3e-158, Method: Compositional matrix adjust.
 Identities = 371/866 (43%), Positives = 567/866 (66%), Gaps = 46/866 (5%)

Query  6    YNPSAIEPKVQQYWAENKVFKAIKDESKPKYYCLSMFPYPSGR-LHMGHVRNYTIGDVVS  64
            Y+ +AIEPK Q +WA+N  FK+  D SKPK+Y L MFPYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  65   RYQRMNGKNVLQPMGWDAFGLPAEGAAVKNKTAPAKWTYENIEYMKNQLKALGFGFDWDR  124
            R++R +G NVL+PMGWDAFGLPAE  A+     PA  T ENI   K Q++ALGF++DWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  125  EVTTCRPEYYKWEQWFFTELYKKGLVYKKTSTVNWCPNDETVLANEQV-HEGCCWRCDTP  183
            EV T  P+YYKW QW+FT LY KGL Y     VNW  +  T +ANE+V  +G   R + P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  184  VEQKEIPQWFIKITDYAEQLLNDLDRLPLWPDQVKTMQRNWIGRSEGVEITFKVKGTDQT  243
            V +K + QW +KIT YAE+LL+DL+ +  WP+ +K MQRNWIG+S G ++TFKVK+TD+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  244  LPVYTTRPDTFFGVSYv--avaaahplatlaaENNPALAAFIQEAK-NTKVAEADIATME  300
            + V+TTRPDT+FG +Y   A   A   A  ++++  A+A + ++A  ++ +A +D+A  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  301  KKGMATGLFAIHPLTGEEVPVWVANFVLMHYGTGAVMAVPAHDERDFEFAQKYNLPIKQV  360
            K G+ TG +AI+P+ G E+PVW+A++VL  YGTGA+MAVPAHDERD EFA+++NL   ++
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNL---DI  358

Query  361  IVPLDGSEWDFSKAAMTEHGKLINSAEFDGLDFDGAFKGIADKLEGMGIGKRQVNYRLRD  420
            I  L+G+  +   AA TE+G  INS  +DGLD  +A+  + + LE+ G+G+ +V YRLRD
Sbjct  359  IPVLEGG--NVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  421  WGVSRQRYWGAPIPMLTLENGETVTVPMQDLPVVLP--EDVVMDGV-KSPIKADPEWAKT  477
            W  SRQRYWG PIP++  E+G + +VP  +LP+VLP   D+   G   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  478  TY-NGQPALRETDTFDTFMESSWYYARYASPQYQQGMLDKEEANYWLPVDQYIGGIEHAT  536
            T  +G  + RET+T      SSWYY RY  P+  + + D E  + WLPVD Y+GG EHA 
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  537  MHLLYFRFFHKLLRDAGFVTSDEPTEKLLCQGMVLADAYYYTSPTNERIWVSPTEVTVER  596
            +HLLY RF HK+L D G V + EP +KL+ QGM+L+ +Y      + R     + V+ ++
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSR----GALVATDK  587

Query  597  DEKGRILKAFDKEGRALVHSGMTKMSKSKNNGIDPQEMVEKYGADTVRLFMMFASPAEMT  656
             EK R    F+ E    ++ + +KMSKS +N ++P+++VE+YGADT+R++ MF +P + +
Sbjct  588  VEK-RDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  657  LEWQESGVEGAKRFLGRLWNLAYEYAQSPATVALDPTALSKEQKDLRRDVHKTIAKVSDD  716
            + W E G+EG+++FL+R+    Y    +      ++ AL K  ++       T+  V+++
Sbjct  647  IAWSEEGLEGSRKFLDRV----YRLITTKEITEENSGALDKVYNE-------TVKAVTEQ  695

Query  717  IGRRQTFNTAIAAIMELMNKLTKAPLVNDQDKAVMAEALNAVIRMLYPITPHICFELWQA  776
            +++ + FNTAIA +M ++N         +++  + ++  ++ ++++ P++PH+  ELWQA
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  777  LGNEG-SIDFAPWVVADEKAMVEDEKLVVVQVNGKVRGKITVSATATEDEVKAIAKADEN  835
            L   G SI + PW   DE  +VE++  +VVQ++GKV++K+ V+   + +E++ +A A+E+
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  836  VAKYLEGVEIVKEIYVPFKMLSFAVK  861
            V   + G +I+K I VP K++++ +K
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVIK  833

964) leuS in NC_009342


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  552 bits (2084),  Expect = 4e-158, Method: Compositional matrix adjust.
 Identities = 357/739 (49%), Positives = 504/739 (69%), Gaps = 59/739 (7%)

Query  220  LVYRSNSTVNWCPGLGTVLANEEVTADGRSERGNFPVFRKNLSQWMMRITAYSDRLIDDL  279
            L Y ++  VNW   LGT +ANEEV +DG SERG +PV RK + QWM++ITAY++RL++DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  280  ELLDWTEKVKSMQRNWIGRSRGAEVDFSAE--GETVTVFTTRPDTLFGATYMVLAPEHEL  337
            E +DW E +K MQRNWIG+S GA+V F     +   TVFTTRPDTLFGATY VLAPEH L
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  338  VDVLLEKAGSYEGVDARWTNGQASPAEAVAAYRASIAAKSDLERQE-NKEKTGVFLGVYA  396
            VD +                  +  AEAVA Y+   + KSDL R +  KEKTGV  G YA
Sbjct  268  VDAI----------------TTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYA  311

Query  397  TNPVNGDQIPVFIADYVLTGYGTGAIMAVPAHDERDYEFATVLGLPIKEVVAGGNIEEAA  456
             NPVNG ++PV IADYVL++YGTGAIMAVPAHDERD EFA  + L I  V+ GGN+EEAA
Sbjct  312  INPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEAA  371

Query  457  FTESGEAVNSANDNGLDINGLAKDEAVAKTIEWLEEKELGRGTIQYKLRDWLFARQRYWG  516
            FTE G  +NS       ++GL K  A+AK +EWLE   +G   + Y+LRDWLF+RQRYWG
Sbjct  372  FTEDGLHINSDF-----LDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWG  426

Query  517  EPFPIVYDENGQAHALPDSMLPVELPEVEDYKPVSFdpedadsepsppLAKAREWVEVEL  576
            EP+PI+  E+G + A+P+S LP+ LP   D +P +           +PLA+  +W+EV  
Sbjct  427  EPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSG--------TGESPLANVTDWLEVTR  478

Query  577  DLGDGKKKYTRDTNVMPQWAGSSWYQLRYVDPSNDEQFCNIENERYWTGPRPETHGPNDP  636
            +  DG K   R+TN MPQWAGSSWY LRY+DP N E++ + E  + W             
Sbjct  479  E--DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWL------------  523

Query  637  GGVDLYVGGVEHAVLHLLYARFWHKVLFDLGHVSSKEPYRRLYNQGYIQAFAYTDSRGVY  696
              VD+YVGG EHAVLHLLYARFWHKVL+DLG V++KEP+++L+NQG I + +Y DSRG  
Sbjct  524  -PVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGAL  582

Query  697  VPADDVEEKDGKFFY--QGEEVNQEYGKMGKSLKNAVAPDDICNNFGADTLRVYEMAMGP  754
            V++D VE +DG FF    GEE++Q  +KM+KSLKN V PDD+ +++GADTLRVYEM MGP
Sbjct  583  VATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGP  642

Query  755  LDTSRPWATKDVVGAQRFLQRLWRLVVDENTGEVLTRDEVLTDDDNKQLHRTIAGVRDDY  814
            LD+S +W+  ++ G+++FL+R+ RL+   +  E       L    +K  + T+ +V ++ 
Sbjct  643  LDASIAWSEEGLEGSRKFLDRVYRLITTKEITE--ENSGAL----DKVYNETVKAVTEQV  696

Query  815  TNLRVNTVVAKLIEYVNYLTKTYPDTIPAGAVLPLIVMVSPVAPHIAEELWKKL-GHDDT  873
             +++ NT +A+L+ +VN   K   D + ++    ++ +++P APH++EELW+ L + +++
Sbjct  697  DQMKFNTAIAQLMVFVNAANKE--DKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGES  754

Query  874  VTYEPFPTFEEKWLTDDEIELPVQVNGKVRGRITVAADASQEQVIEAALADEKVQEQISG  933
            ++Y P P+++E  L ++++E+ VQ++GKV++++ VA D S+E++ E ALA+EKVQ +I+G
Sbjct  755  ISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAG  814

Query  934  KNLIKQIVVPGRMVNLVVK  952
            K++IK I VP ++VN+V+K
Sbjct  815  KDIIKVIAVPNKLVNIVIK  833


 Score =  141 bits (519),  Expect = 2e-34, Method: Compositional matrix adjust.
 Identities = 79/149 (54%), Positives = 104/149 (70%), Gaps = 11/149 (7%)

Query  23   IEGEWQNYWTDNGTFNAPNPVGDLAPADGKALPEDKLFVQDMFPYPSGAGLHVGHPLGYI  82
            IE  WQ +W+DN TF++           G   +  K++  DMFPYPSGAGLHVGHP GY 
Sbjct  9    IEPKWQAFWADNHTFKT-----------GTDASKPKFYALDMFPYPSGAGLHVGHPEGYT  57

Query  83   ATDVFARYNRMLGKNVLHTLGYDAFGLPAEQYAIQTGTHPRTTTMANIENMKRQLGALGL  142
            ATD+++R++R  G NVLH +G DAFGLPAEQYA++TG +P   T  NI N KRQ+ ALG+
Sbjct  58   ATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGF  117

Query  143  GHDSRRAVATTDPEFYKWTQWIFLQIFNS  171
            + D  R V TTDP++YKWTQWIF ++++ 
Sbjct  118  SYDWDREVNTTDPNYYKWTQWIFTKLYEK  146

965) B711_0708 in NC_018625


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  552 bits (2082),  Expect = 4e-158, Method: Compositional matrix adjust.
 Identities = 334/725 (47%), Positives = 505/725 (70%), Gaps = 25/725 (3%)

Query  1    MGFSYDEGREFATSDPDYYRWTQKLFLFLYEKGLAYMADMAVNYCEELGTVLANEEV-EN  59
            +GFSYD +RE  T+DP+YY+WTQ +F  LYEKGLAY A+++VN  EELGT +ANEEV  +
Sbjct  115  LGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPD  174

Query  60   GLSVEGGYPVERRMLRQWILRITAYSDHLLQGLEDLDWPENVKQLQRNWIGKSEGALVRF  119
            G S  GGYPV R+ +RQW+L+ITAY+++LL++LE++DWPE++K++QRNWIGKS GA V F
Sbjct  175  GTSERGGYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTF  234

Query  120  EV-DNGNFLSVFTTRPDTLCGVSFLVMAPEHPEINHLVSEEQRSAVENYIRCVQSKSERE  178
             V D ++ ++VFTTRPDTL G ++ V+APEH+ ++ + + +Q  AV +Y R    KS+  
Sbjct  235  KVKDTDKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLA  294

Query  179  RISETKVKSGVFIGAYAKHPITGAPLPIWVSDYVIMGYGSGVVMGVPAHDERDREFANAF  238
            R   +K K+GV  G+YA +P+ G  +P+W++DYV+ +YG+G +M+VPAHDERD+EFA+ F
Sbjct  295  RTDLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQF  354

Query  239  ALPISEVLDDNG--------QCIHSNHEDFLLNGLRGKEASDYVIAYLQKKNLGEAKVVY  290
             L I  VL++          + +H N +  +L+GL    A   ++  L+   +G+ +V Y
Sbjct  355  NLDIIPVLEGGNVEEAAFTEDGLHINSD--FLDGLDKASAIAKMVEWLEAEGVGNENVTY  412

Query  291  KLRDWLFSRQRYWGEPIPIIHFEDGTCRpleddelpllppeIQDYRPKGFGQGPLANVKE  350
            +LRDWLFSRQRYWGEPIPIIH EDGT  ++ + ELPL+ P  +D RP G G++PLANV +
Sbjct  413  RLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTD  472

Query  351  WVEIHDVKTNRKGRRETHTMPQWAGSCWYYLRFCDAHNSQAPWSNENERYWMPVDLYIGG  410
            W+E+       KGRRET+TMPQWAGS WYYLR+ D+HN++    +E  + W+PVD+Y+GG
Sbjct  473  WLEVTR-EDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGG  531

Query  411  AEHAVLHLLYSRFWHRVFYEAGLVSTPEPFKKLINQGLVLATSYRIPGKGYVHPEDVRED  470
            AEHAVLHLLY+RFWH+V+Y+ G+V+T EPF+KL+NQG++L+TSYR +  + V  + V   
Sbjct  532  AEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKR  591

Query  471  NGK-WTTASGEELEVRQEKMSKSKLNGVDPQTLIDEFGADALRMYAMFSGPLDKNKLWCN  529
            +G      +GEELE    KMSKS  N V+P+ +++++GAD+LR+Y MF GPLD +  W +
Sbjct  592  DGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSE  651

Query  530  HGVSGCRRFLNRFYELVTSSAVQDVDDPKGMALAHKLVHRVGEDIEKMSLNTIPSSFMEF  589
            +G+ G R+FL+R Y L+T+  + + +      + +  V  V E++++M +NT  + +M F
Sbjct  652  EGLEGSRKFLDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVF  711

Query  590  INEFTK----LDTYPKSALAMVVRALAPIAPHISEELWTIL-GYAPGIDKAGWPEVDPKY  644
            +N   K    +  Y+K+ + ++    AP+APH++EELW  L + + +I    WP  D   
Sbjct  712  VNAANKEDKLFSDYAKGFVQLI----APFAPHLGEELWQALTASGESISYVPWPSYDESK  767

Query  645  LEDASVTFVIQVNGKLRARLDIDKNTSQEDI--LSAARESVAKYLEDKEIKKEVFVPNRL  702
            L +  V +V+Q++GK++A+L + K+ S+E++  ++ A E V   + +K+I K + VPN+L
Sbjct  768  LVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKL  827

Query  703  VNFVL  707
            VN+V+
Sbjct  828  VNIVI  832

966) leuS in NC_016613


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  552 bits (2084),  Expect = 4e-158, Method: Compositional matrix adjust.
 Identities = 379/867 (44%), Positives = 570/867 (66%), Gaps = 50/867 (5%)

Query  5    YNPQDIEQKVQKHWDDNKTFVVSEDPNKEKFYCLSMFPYPSGR-LHMGHVRNYTIGDVVS  63
            Y+   IE K Q  W DN TF  + D++K KFY L MFPYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RFQRLQGKNVMQPIGWDAFGLPAENAAVKNKTAPAPWTYENIEYMKNQLKLLGFGYDWNR  123
            RF+R QG NV++P+GWDAFGLPAE+ A+     PA  T ENI   K Q++ LGF+YDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EFATCTPEYYRWEQEFFTKLYEKGLVYKKTSSVNWCPNDQTVLANEQV-EDGCCWRCDTP  182
            E  T  P+YY+W Q +FTKLYEKGL Y    +VNW  +  T +ANE+V  DG   R + P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VEQKEIPQWFIKITEYAQELLDDLDNLDGWPEMVKTMQRNWIGRSEGVELKFQVKDQAQD  242
            V +K + QW +KIT YA+ LL+DL+++D WPE +K MQRNWIG+S G ++ F+VKD  +D
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LEVYTTRPDTLMGVTYVGIaaghplaalaaennpelaaFIDECKNNKVAEAELA----TM  298
            + V+TTRPDTL G TY  +A+ H+L    + ++   A  + + K +    ++LA    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEA--VADYKRQASLKSDLARTDLAK  300

Query  299  EKKGMATGLTAIHPLNGREVPVYVANFVLMDYGTGAVMAVPAHDQRDYEFATKYGLDIVP  358
            EK G+ TG  AI+P+NG+E+PV +A++VL  YGTGA+MAVPAHD+RD EFA ++ LDI+P
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VIKPVDGSELDVSEAAYTEKGVLFDSGEFDGLEFQAAFDAIAAKLEAEGKGTKTVNFRLR  418
            V+   +G+  +V EAA+TE G+ ++S+ +DGL+  +A+  +   LEAEG G   V +RLR
Sbjct  361  VL---EGG--NVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  419  DWGVSRQRYWGAPIPMVTTEDGEVHPVPADQLPVILP--EDVVMDGVT-SPIKADKEWAK  475
            DW  SRQRYWG PIP++  EDG   +VP  +LP++LP   D+   G   SP+    +W  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  476  TTFNSE-PALRETDTFDTFMESSWYYARYCSPQADDIL-DPEKANYWLPVDQYIGGIEHA  533
             T +    + RET+T      SSWYY RY  P+  + L D E  + WLPVD Y+GG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  534  CMHLLYSRFFHKLLRDAGYVTSDEPFKQLLCQGMVLADAFYFENEKGGKEWVAPTDVKVE  593
             +HLLY+RF HK+L D G V + EPF++L+ QGM+L+ +  + + +G+   + +TD KVE
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS--YRDSRGA---LVATD-KVE  589

Query  594  RDGKGRITSATDNEGRNVEHSGMIKMSKSKNNGIDPQEMVDKYGADTVRLFMMFASPADM  653
            + + + +   T++E   +E++   KMSKS +N ++P+++V++YGADT+R++ MF +P D 
Sbjct  590  KRDGSFFHVETGEE---LEQAP-AKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  654  TLEWQESGVEGANRFLKRVWKLVKEHTAKGAAEAVNADALSGDQKALRRDVHKTIAKVTD  713
            ++ W E G+EG+ +FL RV +L+   T+K  +E  ++        AL +  + T+  VT+
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLI---TTKEITEENSG--------ALDKVYNETVKAVTE  694

Query  714  DVARRQTFNTAIAAIMELMNKLAKAPQESAQDRAILDEALKAVVAMLYPITPHISYELWT  773
            +V + + FNTAIA +M ++N        + ++  ++ +  K+ V ++ P++PH++ ELW 
Sbjct  695  QVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  774  ALGETD--IDNAAWPTFDEKALVEDEKTIVVQVNGKLRAKLTVAADATKEQVEELGLNDE  831
            AL  ++  I   +WP++DE  LVE++  IVVQ++GK++AKL VA D ++E+++E++L +E
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  832  NVTKFTEDKTIRKVIYVPGKLLNIVAN  858
            +V     +K I KVI VP KL+NIV +
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVIK  833

967) RMDY18_11170 in NC_013715


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  552 bits (2084),  Expect = 4e-158, Method: Compositional matrix adjust.
 Identities = 364/855 (43%), Positives = 545/855 (64%), Gaps = 63/855 (7%)

Query  14   YDFRAMEAKWRPYWDETKVFQPTGDAPKGRKYVLDMFPYPSG-DLHMGHAEAFAIGDMNA  72
            YD  A+E+KW+++W +   F+   DA+K + Y LDMFPYPSG +LH+GH+E+++  D+ +
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  73   RYFKQCGYDVLHPIGWDSFGLPAENAAIKNDTHPKEWTYKNIETQAESFKRYAIAADWSR  132
            R+ +  G +VLHP+GWD+FGLPAE+ A+  + +P E T  NI      ++  +++ DW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  133  RLHTSDPEYYKWTQWLFEQFYKKGLAYRKDSMVNWCPKDQTVLANEQVV-NGACERCGTT  191
             ++T+DP+YYKWTQW+F ++Y KGLAY  +  VNW     T +ANE+V+ +G+ ER G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  192  VTKKSLNQWYFKITDYAQQLLDDMEQLEGKWPDRVLLMQRNWIGRSEGAEVRFEIEATED  251
            V +K++ QW +KIT YA++LL+D+E+++  WP+ +  MQRNWIG+S GA+V F +  T+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD--WPESIKDMQRNWIGKSTGANVTFKVKDTDK  241

Query  252  QAAESFTVFTTRPDTLYGATFIVVAADAAFAEQIVAPEHKAALEQYREDIKALSDIDRQS  311
            +    FTVFTTRPDTL+GAT+ V+A++ A+ + I ++++  A+ +Y+ +    SD+ R  
Sbjct  242  D----FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTD  297

Query  312  SDREKTGVFTGRYAINPLTGAKLPVWASDYVLADYGTGAIMAVPAHDQRDLEFALKFDLP  371
              +EKTGV TG YAINP+ G  +PVW +DYVLA YGTGAIMAVPAHD+RD EFA +F+L 
Sbjct  298  LAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLD  357

Query  372  IVKVLDVEGAEDPATSGVAASGDGVLINSGELTGLPKAEALAKAIELVEAAGTGEGKVIY  431
            I+ VL+    E++A      + DG+ INS+ L GL KA A+AK +E +EA G G+ +V Y
Sbjct  358  IIPVLEGGNVEEAAF-----TEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTY  412

Query  432  RLRDWLLSRQRFWGTPIPVIHCEDCGEVLVPEDQLPVLLPDNLRGEQLAPKGQSPLAAAD  491
            RLRDWL+SRQR+WG PIP+IH ED     VPE +LP++LP   ++ + +  G+SPLA   
Sbjct  413  RLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVT-KDIRPSGTGESPLANVT  471

Query  492  DWAIVPCPKCGKQARRDSDTMDTFVDSSWYFLRYVSPNYDKAPFDPQAMSEWGAVDMYVG  551
            DW  V     G ++RR+++TM    +SSWY+LRY+ P+      D + + +W +VD+YVG
Sbjct  472  DWLEVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVG  530

Query  552  GVEHAILHLLYARFFTKVVRDLGLIKHDEPFKALMNQGQVLNGG----------------  595
            G EHA+LHLLYARF  KV+ DLG++   EPF+ L NQG +L  +                
Sbjct  531  GAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEK  590

Query  596  ------------------KAMSKSLGNGVNLGEQLDKFGVDAIRTTMIFASPPEDDVDWA  637
                                MSKSL N VN ++ ++++G D++R   +F +P +  + W+
Sbjct  591  RDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWS  650

Query  638  DVSPSGSQKFLARAWRVAQDVTSEPGVDATTGDLELQKLIARTVHEVQGLLDNGKFNVVV  697
            + +  GS+KFL R  R+   +T+    +  +G L+  K+   TV  V   +D+ KFN  +
Sbjct  651  EEGLEGSRKFLDRVYRL---ITTKEITEENSGALD--KVYNETVKAVTEQVDQMKFNTAI  705

Query  698  AKTMELVNATRKAIDSGAGAADPAVRKAAETIAILLSLYAPYTAEDVWHALGHDTPVLT-  756
            A+ M +VNA+ K         D      A  +  L++ +AP  +E++W+AL      ++ 
Sbjct  706  AQLMVFVNAANK--------EDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISY  757

Query  757  AGFPEVDPALLVDDTVTAIVQIKGKVKARLEVAKDISeqelqelaladaavqRSIGDAEI  816
               P  D + LV++ V  +VQIKGKVKA+L VAKD+S +ELQE+ALA+  VQ  I++ +I
Sbjct  758  VPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDI  817

Query  817  RKVIVRAPKLVNIVI  831
             KVI  + KLVNIVI
Sbjct  818  IKVIAVPNKLVNIVI  832

968) SerAS12_1179 in NC_015566


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  552 bits (2083),  Expect = 4e-158, Method: Compositional matrix adjust.
 Identities = 367/866 (43%), Positives = 556/866 (65%), Gaps = 48/866 (5%)

Query  5    YRPEDIESNVQLHWQEKQTFKVTEDASKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIS  63
            Y    IE++ Q  W +++TFK   DASK K+Y L M+PYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIEYMKNQLKLLGFGYDWDR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NI   K Q++ LGF+YDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EIATCDPDYYRWEQWFFTKLYEKGLVYKKTSAVNWCPHDLTVLANEQVI-DGCCWRCDTK  182
            E+ T DP+YY+W QW+FTKLYEKGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITDYADQLLNDLDTLESWPEQVKTMQRNWIGRSEGVDITFDVAGSDEK  242
            V RK + QW +KIT YA++LL+DL+ ++ WPE +K MQRNWIG+S G ++TF V ++D  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGATYVAVAAGHPLAQQGAVNNPALAEFIEECRNTKVAEADMA----TM  298
            +TV+TTRPDT+ GATY  +A+ H+L +  A+  +  AE + + +      +D+A    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVD--AITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  299  EKKGMPTGLFAIHPLSGEKVPVWVANFVLMEYGTGAVMAVPAHDQRDWEFATKYGLPIKP  358
            EK G+ TG +AI+P++G  +PVW+A++VL  YGTGA+MAVPAHD+RDWEFA ++ L I P
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VVLTLDGSQPDVHAEAMTEKGALFNSGEFDGLDHEAGFNAIADKLVAKGVGQRKVNYRLR  418
            V   L+G+  +V+  A TE G  +NS+ +DGLD  +++  + + L A GVG+ +V YRLR
Sbjct  361  V---LEGG--NVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  419  DWGVSRQRYWGAPIPMVTLEDGTVMPTPEDQLPVILP--EDVVMDGIT-SPIKADPEWAK  475
            DW  SRQRYWG PIP++  EDGT  + PE +LP++LP   D+   G   SP+    +W  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  476  TT-VNGQPALRETDTFDTFMESSWYYARYTCPQYDQGMLDPAAANYWLPVDQYVGGIEHA  534
             T  +G  + RET+T      SSWYY RY  P+  + + D    + WLPVD YVGG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  535  IMHLMYFRFFHKLLRDAGMVDSDEPAKRLLCQGMVLADAFYYTGNSGERVWVSPVDATVE  594
            ++HL+Y RF HK+L D G+V + EP ++L+ QGM+L+ +  Y ++ G  V        VE
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS--YRDSRGALV----ATDKVE  589

Query  595  RDDKGRIVKATDPQGRELVYAGMSKMSKSKNNGIDPQVMVEKYGADTVRLFMMFASPAEM  654
            + D G +      +  E    + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P + 
Sbjct  590  KRD-GSFFHVETGEELE---QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  655  TLEWQESGVEGANRFLKRVWKLAYEHLEKGAVQPLNVAALNEDQKALRRDLHKTIAKVTD  714
            ++ W E G+EG+ +FL RV +L         +   +++  +E+  AL +  + T+  VT+
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRL---------ITTKEIT--EENSGALDKVYNETVKAVTE  694

Query  715  DIGRRQTFNTAIAAVMELMNKLARAPQESEQDRALLQEALLSVVRMLYPFTPHVCFSLWQ  774
            ++++ + FNTAIA +M ++N        ++++  L+ +   + V+++ PF+PH+   LWQ
Sbjct  695  QVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  775  ALGGEGD-VDTAAWPQADEQAMVEDSKLVVVQVNGKVRAKITVAADATEEQVRARAAEEH  833
            AL + G+ +   +WP  DE  +VE+   +VVQ++GKV+AK+ VA D + E+++  A  ++
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  834  LVAKYLDGVTVRKVIYVPGKLLNLVV  859
             V   + G  + KVI VP KL+N+V+
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVI  832

969) SerAS13_1179 in NC_017573


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  552 bits (2083),  Expect = 4e-158, Method: Compositional matrix adjust.
 Identities = 367/866 (43%), Positives = 556/866 (65%), Gaps = 48/866 (5%)

Query  5    YRPEDIESNVQLHWQEKQTFKVTEDASKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIS  63
            Y    IE++ Q  W +++TFK   DASK K+Y L M+PYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIEYMKNQLKLLGFGYDWDR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NI   K Q++ LGF+YDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EIATCDPDYYRWEQWFFTKLYEKGLVYKKTSAVNWCPHDLTVLANEQVI-DGCCWRCDTK  182
            E+ T DP+YY+W QW+FTKLYEKGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITDYADQLLNDLDTLESWPEQVKTMQRNWIGRSEGVDITFDVAGSDEK  242
            V RK + QW +KIT YA++LL+DL+ ++ WPE +K MQRNWIG+S G ++TF V ++D  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGATYVAVAAGHPLAQQGAVNNPALAEFIEECRNTKVAEADMA----TM  298
            +TV+TTRPDT+ GATY  +A+ H+L +  A+  +  AE + + +      +D+A    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVD--AITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  299  EKKGMPTGLFAIHPLSGEKVPVWVANFVLMEYGTGAVMAVPAHDQRDWEFATKYGLPIKP  358
            EK G+ TG +AI+P++G  +PVW+A++VL  YGTGA+MAVPAHD+RDWEFA ++ L I P
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VVLTLDGSQPDVHAEAMTEKGALFNSGEFDGLDHEAGFNAIADKLVAKGVGQRKVNYRLR  418
            V   L+G+  +V+  A TE G  +NS+ +DGLD  +++  + + L A GVG+ +V YRLR
Sbjct  361  V---LEGG--NVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  419  DWGVSRQRYWGAPIPMVTLEDGTVMPTPEDQLPVILP--EDVVMDGIT-SPIKADPEWAK  475
            DW  SRQRYWG PIP++  EDGT  + PE +LP++LP   D+   G   SP+    +W  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  476  TT-VNGQPALRETDTFDTFMESSWYYARYTCPQYDQGMLDPAAANYWLPVDQYVGGIEHA  534
             T  +G  + RET+T      SSWYY RY  P+  + + D    + WLPVD YVGG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  535  IMHLMYFRFFHKLLRDAGMVDSDEPAKRLLCQGMVLADAFYYTGNSGERVWVSPVDATVE  594
            ++HL+Y RF HK+L D G+V + EP ++L+ QGM+L+ +  Y ++ G  V        VE
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS--YRDSRGALV----ATDKVE  589

Query  595  RDDKGRIVKATDPQGRELVYAGMSKMSKSKNNGIDPQVMVEKYGADTVRLFMMFASPAEM  654
            + D G +      +  E    + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P + 
Sbjct  590  KRD-GSFFHVETGEELE---QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  655  TLEWQESGVEGANRFLKRVWKLAYEHLEKGAVQPLNVAALNEDQKALRRDLHKTIAKVTD  714
            ++ W E G+EG+ +FL RV +L         +   +++  +E+  AL +  + T+  VT+
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRL---------ITTKEIT--EENSGALDKVYNETVKAVTE  694

Query  715  DIGRRQTFNTAIAAVMELMNKLARAPQESEQDRALLQEALLSVVRMLYPFTPHVCFSLWQ  774
            ++++ + FNTAIA +M ++N        ++++  L+ +   + V+++ PF+PH+   LWQ
Sbjct  695  QVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  775  ALGGEGD-VDTAAWPQADEQAMVEDSKLVVVQVNGKVRAKITVAADATEEQVRARAAEEH  833
            AL + G+ +   +WP  DE  +VE+   +VVQ++GKV+AK+ VA D + E+++  A  ++
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  834  LVAKYLDGVTVRKVIYVPGKLLNLVV  859
             V   + G  + KVI VP KL+N+V+
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVI  832

970) leuS in NC_021741


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  552 bits (2084),  Expect = 4e-158, Method: Compositional matrix adjust.
 Identities = 364/866 (43%), Positives = 557/866 (65%), Gaps = 48/866 (5%)

Query  5    YRPEDIESNVQLHWEEKQTFKVTEDASKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIS  63
            Y    IE++ Q  W +++TFK   DASK K+Y L M+PYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIEYMKNQLKLLGFGYDWDR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NI   K Q++ LGF+YDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EIATCDPDYYRWEQWFFTKLYEKGLVYKKTSAVNWCPHDLTVLANEQVI-DGCCWRCDTK  182
            E+ T DP+YY+W QW+FTKLYEKGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITDYADQLLNDLDTLESWPEQVKTMQRNWIGRSEGVDITFDVAGSDEK  242
            V RK + QW +KIT YA++LL+DL+ ++ WPE +K MQRNWIG+S G ++TF V ++D  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGATYVAVAAGHPLAQQGAVNNPALAEFIEECRNTKVAEAEMA----TM  298
            +TV+TTRPDT+ GATY  +A+ H+L +  A+  +  AE + + +      +++A    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVD--AITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  299  EKKGMPTGLFAIHPLSGEQVPIWVANFVLMEYGTGAVMAVPAHDQRDWEFATKYGLPIKP  358
            EK G+ TG +AI+P++G ++P+W+A++VL  YGTGA+MAVPAHD+RDWEFA ++ L I P
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VVLALDGSQPDVQAEAMTEKGTLFNSGEFDSLDHQDGFNAIADKLVAKGVGQRKVNYRLR  418
            V   L+G+  +V+  A TE G  +NS+ +D+LD   ++  + + L A GVG+ +V YRLR
Sbjct  361  V---LEGG--NVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  419  DWGVSRQRYWGAPIPMVTLEDGTVMPTPEDQLPVILP--EDVVMDGIT-SPIKADPEWAK  475
            DW  SRQRYWG PIP++  EDGT  + PE +LP++LP   D+   G   SP+    +W  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  476  TT-VNGQPALRETDTFDTFMESSWYYARYTCPQYDQGMLDPAAANYWLPVDQYVGGIEHA  534
             T  +G  + RET+T      SSWYY RY  P+  + + D    + WLPVD YVGG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  535  IMHLMYFRFFHKLLRDAGLVDSDEPAKRLLCQGMVLADAFYYTGNSGERVWVSPVDANVE  594
            ++HL+Y RF HK+L D G+V + EP ++L+ QGM+L+ +  Y ++ G  V       +VE
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS--YRDSRGALV----ATDKVE  589

Query  595  RDDKGRIIKATDPQGRELVYAGMSKMSKSKNNGIDPQVMVEKYGADTVRLFMMFASPAEM  654
            + D G ++     +  E    + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P + 
Sbjct  590  KRD-GSFFHVETGEELE---QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  655  TLEWQESGVEGANRFLKRVWKLAYEHLEKGAVQPLNVATLSEDQKALRRDLHKTIAKVTD  714
            ++ W E G+EG+ +FL RV +L         +   +++   E+  AL +  + T+  VT+
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRL---------ITTKEIT--EENSGALDKVYNETVKAVTE  694

Query  715  DIGRRQTFNTAIAAVMELMNKLARAPQESEQDRALLQEALLAVVRMLYPFTPHVCFSLWQ  774
            ++++ + FNTAIA +M ++N        ++++  L+ +   + V+++ PF+PH+   LWQ
Sbjct  695  QVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  775  ALGGEGD-VDTAAWPQADEQAMVEDSKLVVVQVNGKVRAKITVAADATEEQVRARAAEEH  833
            AL + G+ +   +WP  DE  +VE+   +VVQ++GKV+AK+ VA D + E+++  A  ++
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  834  LVAKYLDGVTVRKVIYVPGKLLNLVV  859
             V   + G  + KVI VP KL+N+V+
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVI  832

971) SerAS9_1179 in NC_015567


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  552 bits (2083),  Expect = 4e-158, Method: Compositional matrix adjust.
 Identities = 367/866 (43%), Positives = 556/866 (65%), Gaps = 48/866 (5%)

Query  5    YRPEDIESNVQLHWQEKQTFKVTEDASKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIS  63
            Y    IE++ Q  W +++TFK   DASK K+Y L M+PYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIEYMKNQLKLLGFGYDWDR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NI   K Q++ LGF+YDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EIATCDPDYYRWEQWFFTKLYEKGLVYKKTSAVNWCPHDLTVLANEQVI-DGCCWRCDTK  182
            E+ T DP+YY+W QW+FTKLYEKGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITDYADQLLNDLDTLESWPEQVKTMQRNWIGRSEGVDITFDVAGSDEK  242
            V RK + QW +KIT YA++LL+DL+ ++ WPE +K MQRNWIG+S G ++TF V ++D  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGATYVAVAAGHPLAQQGAVNNPALAEFIEECRNTKVAEADMA----TM  298
            +TV+TTRPDT+ GATY  +A+ H+L +  A+  +  AE + + +      +D+A    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVD--AITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  299  EKKGMPTGLFAIHPLSGEKVPVWVANFVLMEYGTGAVMAVPAHDQRDWEFATKYGLPIKP  358
            EK G+ TG +AI+P++G  +PVW+A++VL  YGTGA+MAVPAHD+RDWEFA ++ L I P
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VVLTLDGSQPDVHAEAMTEKGALFNSGEFDGLDHEAGFNAIADKLVAKGVGQRKVNYRLR  418
            V   L+G+  +V+  A TE G  +NS+ +DGLD  +++  + + L A GVG+ +V YRLR
Sbjct  361  V---LEGG--NVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  419  DWGVSRQRYWGAPIPMVTLEDGTVMPTPEDQLPVILP--EDVVMDGIT-SPIKADPEWAK  475
            DW  SRQRYWG PIP++  EDGT  + PE +LP++LP   D+   G   SP+    +W  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  476  TT-VNGQPALRETDTFDTFMESSWYYARYTCPQYDQGMLDPAAANYWLPVDQYVGGIEHA  534
             T  +G  + RET+T      SSWYY RY  P+  + + D    + WLPVD YVGG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  535  IMHLMYFRFFHKLLRDAGMVDSDEPAKRLLCQGMVLADAFYYTGNSGERVWVSPVDATVE  594
            ++HL+Y RF HK+L D G+V + EP ++L+ QGM+L+ +  Y ++ G  V        VE
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS--YRDSRGALV----ATDKVE  589

Query  595  RDDKGRIVKATDPQGRELVYAGMSKMSKSKNNGIDPQVMVEKYGADTVRLFMMFASPAEM  654
            + D G +      +  E    + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P + 
Sbjct  590  KRD-GSFFHVETGEELE---QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  655  TLEWQESGVEGANRFLKRVWKLAYEHLEKGAVQPLNVAALNEDQKALRRDLHKTIAKVTD  714
            ++ W E G+EG+ +FL RV +L         +   +++  +E+  AL +  + T+  VT+
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRL---------ITTKEIT--EENSGALDKVYNETVKAVTE  694

Query  715  DIGRRQTFNTAIAAVMELMNKLARAPQESEQDRALLQEALLSVVRMLYPFTPHVCFSLWQ  774
            ++++ + FNTAIA +M ++N        ++++  L+ +   + V+++ PF+PH+   LWQ
Sbjct  695  QVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  775  ALGGEGD-VDTAAWPQADEQAMVEDSKLVVVQVNGKVRAKITVAADATEEQVRARAAEEH  833
            AL + G+ +   +WP  DE  +VE+   +VVQ++GKV+AK+ VA D + E+++  A  ++
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  834  LVAKYLDGVTVRKVIYVPGKLLNLVV  859
             V   + G  + KVI VP KL+N+V+
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVI  832

972) leuS in NC_012796


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  552 bits (2084),  Expect = 4e-158, Method: Compositional matrix adjust.
 Identities = 363/876 (42%), Positives = 545/876 (63%), Gaps = 82/876 (9%)

Query  1    MSKYVPEDVERKWQRIWEEGGHFHVEADPSKPKYYVLEMFPYPSGR-IHMGHVRNYSIGD  59
            M+ Y    +E KWQ +W +   F   +D+SKPK+Y L+MFPYPSG  +H+GH   Y+  D
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  60   VVARFKRMEGHNVLHPMGWDAFGMPAENAAIKHKLHPAAWTISNIDSMRTQLQRLGYSYD  119
            +++RFKR +GHNVLHPMGWDAFG+PAE+ A+    +PA  T  NI + + Q++ LG+SYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  120  WRREIATCHPGYYVHEQRFFLKFLEKGLVYRKHSPQNWCETCGTVLANEQVI-DGCCWRC  178
            W RE+ T +P YY   Q++F K+ EKGL Y  + P NW E  GT +ANE+V+ DG   R 
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  179  DQAVVQKDLEQWFLRITDYAEELLADLDQLVGGWPERVLTMQRNWIGKSVGAEITFKLAE  238
            + +VV+K + QW L+IT YAE LL DL+++  +WPE +  MQRNWIGKS GA++TFK+ +
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEV--DWPESIKDMQRNWIGKSTGANVTFKVKD  238

Query  239  PVAGSEGVTVFTTRPDTLFGATFMSLAAEHPLVPSLIAGKPQEAAVNAFVEKVRNMDRIV  298
                  + TVFTTRPDTLFGAT+  LA+EH+LV ++ ++  Q  AV  +  +      + 
Sbjct  239  T---DKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSD-QAEAVADYKRQASLKSDLA  294

Query  299  RSADDLEKEGVFTGAYCVNPATGKQIPIYVANFVLMGYGTGAVMAVPAHDQRDFEFARKY  358
            R+    EK GV TG+Y +NP  GK++P+ +A++VL +YGTGA+MAVPAHD+RD EFA+++
Sbjct  295  RTDLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQF  354

Query  359  DLPLTVVIEPKGETLDASAMTAAYTDPGVLTASEQFTGMDNEAAKAAIIDWLDGSGRGKK  418
            +L +  V+E  G  ++     AA+T+ G+   S+ + G+D+ +A A +++WL++ G G+ 
Sbjct  355  NLDIIPVLE--GGNVEE----AAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNE  408

Query  419  SINYRLRDWNISRQRYWGAPIPVIYCESCGIVPVPDADLPVELP--RDLALMPDGRSPLP  476
            ++ YRLRDW +SRQRYWG PIP+I  E     +VP+++LP+ LP  +D+     G SPL+
Sbjct  409  NVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLA  468

Query  477  HSPSFTDVACPKCGGKARRETDTLDTFFESSWYFARYASAREAGRPFDPAELAYWLPVDQ  536
            +     +V+    G K+RRET+T+     SSWY+ RY  ++++ +  D   L  WLPVD 
Sbjct  469  NVTDWLEVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDI  527

Query  537  YIGGIEHAILHLLYSRFFVKALRDLGYVGFDEPFANLLTQGMVI----------------  580
            Y+GG EHA+LHLLY+RF  K L DLG V   EPF +L+ QGM++                
Sbjct  528  YVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDK  587

Query  581  ---KDGS---------------KMSKSKGNVVDPDLMIGKYGADTVRVFILFAAPPEKDL  622
               +DGS               KMSKS  NVV+PD ++ +YGADT+RV+ +F +P +  +
Sbjct  588  VEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASI  647

Query  623  EWSDTGIEGASRFLSRLWRLVTEELSGVLTPMPACAPAEVLNLDGLPPLFaelrrrehaa  682
             WS+ G+EG+ +FL R+ RL+T   +  +T   + A   V N + + ++           
Sbjct  648  AWSEEGLEGSRKFLDRVYRLIT---TKEITEENSGALDKVYN-ETVKAV-----------  692

Query  683  aakagadirerFQFNTAIAVAMELVNFLYANVEALRAEPKGAKAVSSAVATLLTVLSPIA  742
                 ++  ++ +FNTAIA  M +VN          A  K  K  S     ++ +++P+A
Sbjct  693  -----TEQVDQMKFNTAIAQLMVFVN----------AANKEDKLFSDYAKGFVQLIAPFA  737

Query  743  PHICEELWQTVGHTSLLLN-EPWPTHDPAALTSDTVEIVVQVCGKLRGKLTVPADADNTA  801
            PH+ EELWQ++  ++  ++  PWP+ D + L  + VEIVVQ+ GK+++KL V+ D     
Sbjct  738  PHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREE  797

Query  802  LEQAALAEPNVAKHIEGKTVRKVIVVPGKLVNVVAN  837
            L++ ALA+ +V  +I GK + KVI VP KLVN+V +
Sbjct  798  LQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

973) leuS in NC_020409


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  552 bits (2084),  Expect = 4e-158, Method: Compositional matrix adjust.
 Identities = 360/868 (42%), Positives = 545/868 (63%), Gaps = 78/868 (8%)

Query  6    YDPEAIEKKWQQEWQNSCCFEVEVDESKPKYYVLEMFPYPSGK-IHMGHVRNYSIGDVVA  64
            YD  AIE KWQ  W ++  F    D SKPK+Y L+MFPYPSG  +H+GH   Y+  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  65   RFKTMQGFNVLHPMGWDAFGLPAENAAIKNETHPAKWTYQNISEMREQLQRLGYSYDWRR  124
            RFK  QG NVLHPMGWDAFGLPAE+ A+    +PA  T +NI++ + Q++ LG+SYDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  125  EIATCRPEYYKWEQKFFLKFLEKGLAYRKDSPQNWCPDCNTVLANEQV-EDGLCWRCDSV  183
            E+ T  P+YYKW Q +F K+ EKGLAY  + P NW  +  T +ANE+V  DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  184  VEQKDMEQWFLRITDYADELLKDLEMLDGGWPERVLTMQRNWIGKSYGAELTFQVKDMAE  243
            V +K M QW L+IT YA+ LL DLE +D  WPE +  MQRNWIGKS GA++TF+VKD   
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD--WPESIKDMQRNWIGKSTGANVTFKVKDTDK  241

Query  244  TITVFTTRPDTVYGATFMSVAAEHPMVESLIAEAENKDEIESFINNIRNMDRIKRGADDL  303
             +TVFTTRPDT++GAT+  +A+EH++V++ I+ +++ + +  +  +      + R     
Sbjct  242  DFTVFTTRPDTLFGATYAVLAPEHALVDA-ITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  304  EKEGIFTGRYCINPVTGAEIPIFIANFVLMGYGTGAVMAVPAHDQRDFEFARKYNLSLKI  363
            EK G+ TG Y INPV G E+P+ IA++VL +YGTGA+MAVPAHD+RD EFA+++NL +  
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  364  VINPKELHDKGEILAESDLEAAYAAPGYLVNSDKFDGMLNEDAKQAIVEHLDSSGKGTMA  423
            V++  +++           EAA++  G  +NSD +DG+ +  A   +VE L++ G G   
Sbjct  361  VLEGGNVE-----------EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNEN  409

Query  424  VNYRLRDWNISRQRFWGAPIPIIYCKECGTVPVPEDQLPLMLPENAQVRKDGK--SPLPQ  481
            V YRLRDW +SRQR+WG PIPII   +  + +VPE +LPL+LP   ++R  G   SPL++
Sbjct  410  VTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLAN  469

Query  482  MEEFVNCDCPHCGKPARRETDTFDTFFESSWYYMRYCDPRNETEPFSQEATDYWMNVDQY  541
            + + ++    +  K +RRET+T      SSWYY+RY DP+N      +E    W+ VD Y
Sbjct  470  VTDWLEVTREDGVK-GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIY  528

Query  542  IGGIEHAILHLLYSRFFTKALRDTGFIKATEPFANLLTQGMVL-----------------  584
            +GG EHA+LHLLY+RF  K L D G + + EPF +L+ QGM+L                 
Sbjct  529  VGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKV  588

Query  585  --KDG---------------GKMSKSKGNVVDPNAMISQYGADATRLFILFASPPIKELE  627
              +DG               +KMSKS  NVV+P+ ++ QYGAD+ R++ +F +P    + 
Sbjct  589  EKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIA  648

Query  628  WSDQGIEGAFRFLNRLWRLVEDQQDRLKPVGPASFDAPQTEAEKQLRFKEHDTIRRATRD  687
            WS++G+EG+ +FL+R+ RL+  ++  +    ++++D            K  +   +A  +
Sbjct  649  WSEEGLEGSRKFLDRVYRLITTKE--ITEENSGALD------------KVYNETVKAVTE  694

Query  688  IENEFQFNTVIAAIMELVNEMYHLKDQLAEENPEALSSAVATA-VTLLSPVTPHICEELW  746
              ++ +FNT IA +M +VN         A ++ + L S  A + V L++P +PH+ EELW
Sbjct  695  QVDQMKFNTAIAQLMVFVN---------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELW  745

Query  747  QA-TGHAQSLTKQAWPIFDEKALVKDEVTMVVQVNGKVRGKFQAPNNAPKDEAEKIALGM  805
            QA T+ ++S++  +WP +DE  LV ++V +VVQ++GKV++K+  +++ +++E + +AL+ 
Sbjct  746  QALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALAN  805

Query  806  ENVVKFIEDKTVRKVIVIPNRLVNIVAN  833
            E+V   I +K + KVI +PN+LVNIV +
Sbjct  806  EKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

974) leuS in NC_010677


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  552 bits (2082),  Expect = 4e-158, Method: Compositional matrix adjust.
 Identities = 355/856 (42%), Positives = 553/856 (65%), Gaps = 72/856 (8%)

Query  4    YNFSDIEKSTQEYWRKNDTFKTIEDNTKEKFYCLSMLPYPSGT-LHMGHVRNYTIGDVIA  62
            Y+ + IE   Q +W  N+TFKT  D +K KFY L M+PYPSG+ LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYQKMQGKNVLHPMGWDAFGLPAENAAIKHKKSPYEWTKSNIAYMRSQFDSLGFSFDWSR  122
            R+++ QG NVLHPMGWDAFGLPAE+ A+   + P E T  NIA  + Q+++LGFS+DW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EIATCDEDYYKWEQWFFIQLYKKGLAYRKNSVVNW-DPVDQTVLANEQVVDGRGWRSGAL  181
            E+ T D +YYKW QW+F +LY KGLAY  +  VNW + ++ ++  +E + DG + R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VEKKEIPQWFLKITDYADELLQDINKLDNWPEAVKTMQINWIGKSKGLTVKFKVKDSNQE  241
            V +K + QW LKIT YA+ LL+D++ +D WPE++K MQ NWIGKS G  V FKVKD++++
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  242  IEVFTTRPDTLMGVNYLGIAPEHPLALKEAKSNSQLAEFIEECKKTSTMEADLA----TQ  297
            + VFTTRPDTL G  Y  +APEH+L   +A + S+ AE + + K+ +++ +DLA    ++
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALV--DAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  298  EKKGFKTSIKVIHPISAETIDVWVANFVLMGYGSGAVMSVPAHDQRDWEFAQKYNIPLKQ  357
            EK G  T+   I+P+++  + VW+A++VL +YG+GA+M+VPAHD+RDWEFA+++N+ +  
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  358  VIESNDNKLKIDLEKQAFTEKGILINSGEFDSLNFKNAYQAIKKYLTEQNKGYETTNFRI  417
            V+E+       ++E  AFTE G+ INS+ +D+L+  +A   +   L  +  G E   +R+
Sbjct  361  VLEGG------NVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRL  414

Query  418  HDWGISRQRYWGCPIPMIHCDDCGAVPEKEENLPVRLPTDVALTEAG---SPLKDIPEFI  474
            +DW +SRQRYWG PIP+IH +D  + +  E +LP+ LP    +  +G   SPL ++ + +
Sbjct  415  RDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWL  474

Query  475  NVACPECGKPAKRETDTFDTFFESSWYYARYTCPTANQMLDQEA--NYWLPVDKYIGGIE  532
            +V+  +  K ++RET+T      SSWYY RY  P   + L +E   + WLPVD Y+GG E
Sbjct  475  EVTREDGVK-GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAE  533

Query  533  HAIMHLLYARFFHKLMRDQGLVKSDEPFKNLLTQGMVL-------------------KDG  573
            HA++HLLYARF HK++ D G+V + EPF++L+ QGM+L                   +DG
Sbjct  534  HAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDG  593

Query  574  ---------------AKMSKSKGNIVDPQELIDKYGADTVRLFSMFAAPPEQSLEWSETG  618
                           AKMSKS  N+V+P++++++YGADT+R++ MF +P + S+ WSE G
Sbjct  594  SFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEG  653

Query  619  VEGTNKFLRKVFNYAELNKVIFAKNITLESQKLTKEDKKARFEIHSNLKQAIFDFDKSQF  678
            +EG+ KFL +V+     + +   ++ +L+  K+ +E  KA   +  ++ Q  F+   +Q+
Sbjct  654  LEGSRKFLDRVYRLITTKEITEENSGALD--KVYNETVKA---VTEQVDQMKFNTAIAQL  708

Query  679  NTVVSACMKILNTLNNYDNLSESVKVEGFSILLRILAPFTPHLCHYLWQQLNL-GEDILH  737
               V+A  K  + +++Y +        GF   ++++APF+PHL + LWQ L   GE I  
Sbjct  709  MVFVNAANKEDKLFSDYAK--------GF---VQLIAPFAPHLGEELWQALTASGESISY  757

Query  738  TSFPTVDNNALEKDEFLLVVQINGKLKAKLELDASLSSNQVEEVVLADEHVKSFIDNKQV  797
             + P+ D++ L  ++  +VVQI+GK+KAKL +   LS ++++EV LA+E V++ I  K++
Sbjct  758  VPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDI  817

Query  798  VKVIYVPQKLINIVIK  813
            +KVI VP+KL+NIVIK
Sbjct  818  IKVIAVPNKLVNIVIK  833

975) Ping_1191 in NC_008709


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  552 bits (2083),  Expect = 4e-158, Method: Compositional matrix adjust.
 Identities = 361/866 (42%), Positives = 568/866 (66%), Gaps = 45/866 (5%)

Query  4    LYNPKEIEKKFQTNWDENQSFKATEDPSKEKYYCLSMFPYPSGK-LHMGHVRNYTIGDVI  62
            +Y+   IE K Q+ W +N++FK+  D+SK K+Y L MFPYPSG  LH+GH   YT  D++
Sbjct  3    FYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDIL  62

Query  63   SRYQRMQGKNVMQPMGWDAFGLPAENAAIKNNTAPAGWTYENIAYMKTQLKQLGFGYDWS  122
            SR++R QG NV++PMGWDAFGLPAE+ A+     PA  T ENIA  K Q++ LGF+YDW 
Sbjct  63   SRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWD  122

Query  123  RELATCQPEYYRWEQWFFTKLVEKDLVYKKMATVNWDPVDQTVLANEQVI-DGRGWRSGA  181
            RE+ T +P+YY+W QW+FTKL EK+L Y     VNW     T +ANE+V+ DG + R+G 
Sbjct  123  REVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGY  182

Query  182  LVEQKEIPQWFIKITAYAQEllddldkldEWPEQVRTMQRNWIGRSEGVEMDFKVSGKEE  241
             V +K + QW +KITAYA E L +     +WPE ++ MQRNWIG+S G ++ FKV + + 
Sbjct  183  PVVRKPMRQWMLKITAYA-ERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDK  241

Query  242  SFSVYTTRPDTVMGVTYVAVAAQHPL--ALEAAKNNPTLAAFCKKCK-NVKLAEAEIATM  298
             F+V+TTRPDT+ G TY  +A++H+L  A+ ++ +  ++A + ++   +  LA +++A  
Sbjct  242  DFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-K  300

Query  299  AKEGVDTGFKAIHPISGLEVPIWTANFVLMGYGSGAVMSVPAHDQRDYEFAKKYDLTIKA  358
             K GV TG  AI+P++G E+P+W A++VL +YG+GA+M+VPAHD+RD EFAK+++L I +
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VIKPANTDLDISVEAYTEKGVCFDSGEFDGLDFSAAFDAVETKLVAENKGKRQVNFRLRD  418
            V+  +N    +   A+TE G+ ++S+ +DGLD ++A+  +   L AE  G+ +V +RLRD
Sbjct  361  VLEGGN----VEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  419  WGVSRQRYWGTPIPMLNLEDGSVVPVPENELPVILP--EDVQMNGIV-SPIKADPDWAKT  475
            W  SRQRYWG PIP+++ EDG+  +VPE+ELP++LP   D++ +G   SP+    DW   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  476  TY-NGQPATHETDTFDTFMESSWYYARYCSPQSDDAMLDPEKANYWLPVDQYIGGIEHAI  534
            T  +G  + +ET+T      SSWYY RY  P++ + + D E  + WLPVD Y+GG EHA+
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  535  LHLLYSRFFHKLLRDFGLVDCDEPYKKLLTQGMVLADAYYYEDAKGGKVWIAPTDVETET  594
            LHLLY+RF HK+L D+G+V   EP++KL+ QGM+L+ +  Y D++G+ V       +   
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS--YRDSRGALV-----ATDKVE  589

Query  595  DEKGKVISAATKDGQTVIYDGMSKMSKSKNNGVDPQVMIDKYGADSVRLFMMFAAPADQT  654
               G  +   T +      ++ +KMSKS +N V+P+ ++++YGAD++R++ MF +P D +
Sbjct  590  KRDGSFFHVETGEELE---QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  655  LEWSDSALEGSLRFLKRLWKIAFDHLALGAVADLDLKSHTEAQKTLRRELHKTIAKVTDD  714
            + WS+ +LEGS +FL R+    +  ++   +++       E   +L +  + T+  VT++
Sbjct  647  IAWSEEGLEGSRKFLDRV----YRLITTKEITE-------ENSGALDKVYNETVKAVTEQ  695

Query  715  IGRRQTFNTAIASVMELMNKLTKTATKTEQDRAILQEALLAITKLLAPITPHICAELFEV  774
            +++ + FNTAIA +M ++N        ++++  ++ +   ++ +L+AP++PH+  EL + 
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  775  LGQTEEILN-APWPTVDESALVEDSKLIVVQVNGKLRAKLTVAADAQQETVQAIAMENEN  833
            L  + E ++  PWP+ DES LVE+   IVVQ++GK++AKL VA D  +E +Q +A+ NE+
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  834  VSKFTDGKTIRKIIFVPGKLLNIVAN  859
            V     GK I K+I VP KL+NIV +
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVIK  833

976) leuS in NC_014330


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  552 bits (2083),  Expect = 4e-158, Method: Compositional matrix adjust.
 Identities = 351/865 (41%), Positives = 555/865 (65%), Gaps = 49/865 (5%)

Query  3    YNFTTIEKKWQKYWKDNQSFKTVSKPTDKKYYVLEMFPYPSGK-MHMGHVSNYTIADSIA  61
            Y+ T+IE KWQ +W DN++FKT + ++  K+Y L+MFPYPSG  +H+GH   YT +D ++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  62   RYYKLLGYDILHPMGWDAFGMPAENAAIEHKTHPAEWTLKNIANMKDQLNLLGYSYDWDR  121
            R+ +  G ++LHPMGWDAFG+PAE+ A++   +PAE T  NIAN K Q+N LG+SYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  122  EVTTCLPDYYKWGQWFILKMYEKGLLYRKGGDVNWCDHCNTVLANEQVTAEGTCWRCDGE  181
            EV T  P+YYKW QW++ K+YEKGL Y     VNW ++  T +ANE+V ++GT  R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VTKKKLEQWYIKVTDYAEQLDADLKLLEGYWPDNVIAMQKNWIGRSVGAYINFNL-DDGK  240
            V +K + QW +K+T YAE+L  DL  ++  WP+++  MQ+NWIG+S GA + F++ D +K
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD--WPESIKDMQRNWIGKSTGANVTFKVKDTDK  241

Query  241  DFPIFTTRPDTIYGVTYMAIAWNYDGLLD-MCTPEQKSAVEEFIKKSA-KID-QKTDYEK  297
            DF +FTTRPDT++G TY  +A   ++L+D + T++Q  AV ++ ++++ K D  +TD  K
Sbjct  242  DFTVFTTRPDTLFGATYAVLA-PEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  298  E--GVFTGRYVVNPFNGEKAPLYAANFVLAEYGSGAVMAVPAHDQRDFEFAKKYNIPVKV  355
            E  GV TG Y +NP NG   P+  A++VLA YG+GA+MAVPAHD+RD EFAK++N+ +  
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  356  VIQNADNSIKAETMTEAYVEDGIVVNSDILNGLSSRDAIKRAIEYATEKGFGKEKVQYKL  415
            V++ ++          A+ EDG+ +NSD+L+GL    AI + +E     G G+E+V Y+L
Sbjct  361  VLEGGNVE------EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRL  414

Query  416  RDWLISRQRYWGNPLPFVHCEKCGVVPVPESELPITLPMDIEF---TVGENPLKKSASFV  472
            RDWL+SRQRYWG+P+P++H E     +VPESELP+ LP+  ++     GE+PL + +  +
Sbjct  415  RDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWL  474

Query  473  NTTCPKCGAPAKRETDTMDTFTCSSWYYARYTDAHNDKMPFDPSSANAWLGVDQYIGGIE  532
            + T    G  ++RET+TM   + SSWYY RY D+HN     D    + WL VD Y+GG E
Sbjct  475  EVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAE  533

Query  533  HACMHLLYSRFWYKFMRDIGLIKGDEPFNRLLTQGMVLANSYEAKSLKKFYTQEQMNNKE  592
            HA +HLLY+RFW K + D+G++   EPF++L+ QGM+L+ SY       + + +++++++
Sbjct  534  HAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSR-GALVATDKVEKRD  592

Query  593  ---YEKDGIKKEDIIVKMEKMSKSKANGVDPAEIIELFGADAVRIFVMFVAPPEKDKEWS  649
               ++ +    E++     KMSKS  N V+P +++E +GAD++R++ MF++P +    WS
Sbjct  593  GSFFHVE--TGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWS  650

Query  650  DEGVKGSARFLNRIWNLFLKYKDEEAFKNAKSFDYNNLSKDGQKLFRKYNktikkvtidi  709
            +EG+ GS +FL+R+  L+                 ++++ +    + K  +   K   + 
Sbjct  651  EEGLEGSRKFLDRVYRLITT---------------KEITEENSGALDKVYNETVKAVTEQ  695

Query  710  kdRFHFNTAIASLMELLNDMSTIKLANNDDYAMFREVIRGYLILLNPIAPHITEELYQIL  769
             D+  FNTAIA LM ++N       A N +  +F +  +G++ L+ P+APH+ EEL Q L
Sbjct  696  VDQMKFNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQAL  748

Query  770  NFGKMIIE-ERWVEHDEQYCKDDTFELVFQVNGKIRDRIEADVNISEDDAKNQALSSDKV  828
              +   I    W   DE    ++  E+V Q++GK++ ++    ++S ++ ++ AL+++KV
Sbjct  749  TASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKV  808

Query  829  KQFTEGKNIVKVVYVKGKLVNIVVK  853
            +    GK+I+KV+ V  KLVNIV+K
Sbjct  809  QAEIAGKDIIKVIAVPNKLVNIVIK  833

977) leuS in NC_021351


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  552 bits (2083),  Expect = 5e-158, Method: Compositional matrix adjust.
 Identities = 356/739 (49%), Positives = 504/739 (69%), Gaps = 59/739 (7%)

Query  220  LVYRSNSTVNWCPGLGTVLANEEVTADGRSERGNFPVFRKNLSQWMMRITAYSDRLIDDL  279
            L Y ++  VNW   LGT +ANEEV +DG SERG +PV RK + QWM++ITAY++RL++DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  280  ELLDWTEKVKSMQRNWIGRSRGAEVDFSAE--GETVTVFTTRPDTLFGATYMVLAPEHEL  337
            E +DW E +K MQRNWIG+S GA+V F     +   TVFTTRPDTLFGATY VLAPEH L
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  338  VDVLLEKAGSYEGVDARWTNGQASPAEAVAAYRASIAAKSDLERQE-NKEKTGVFLGVYA  396
            VD +                  +  AEAVA Y+   + KSDL R +  KEKTGV  G YA
Sbjct  268  VDAI----------------TTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYA  311

Query  397  TNPVNGDQIPVFIADYVLTGYGTGAIMTVPAHDERDYEFATVLGLPIKEVVAGGNIEEAA  456
             NPVNG ++PV IADYVL++YGTGAIM+VPAHDERD EFA  + L I  V+ GGN+EEAA
Sbjct  312  INPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEAA  371

Query  457  FTESGEAVNSANDNGLDINGLAKDEAVAKTIEWLEEKELGRGTIQYKLRDWLFARQRYWG  516
            FTE G  +NS       ++GL K  A+AK +EWLE   +G   + Y+LRDWLF+RQRYWG
Sbjct  372  FTEDGLHINSDF-----LDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWG  426

Query  517  EPFPIVYDENGQAHALPDSMLPVELPEVEDYKPVSFdpedadsepsppLAKAREWVEVEL  576
            EP+PI+  E+G + A+P+S LP+ LP   D +P +           +PLA+  +W+EV  
Sbjct  427  EPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSG--------TGESPLANVTDWLEVTR  478

Query  577  DLGDGKKKYTRDTNVMPQWAGSSWYQLRYVDPSNDEQFCNIENERYWTGPRPETHGPNDP  636
            +  DG K   R+TN MPQWAGSSWY LRY+DP N E++ + E  + W             
Sbjct  479  E--DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWL------------  523

Query  637  GGVDLYVGGVEHAVLHLLYARFWHKVLFDLGHVSSKEPYRRLYNQGYIQAFAYTDSRGVY  696
              VD+YVGG EHAVLHLLYARFWHKVL+DLG V++KEP+++L+NQG I + +Y DSRG  
Sbjct  524  -PVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGAL  582

Query  697  VPADDVEEKDGKFFY--QGEEVNQEYGKMGKSLKNAVAPDDICNNFGADTLRVYEMAMGP  754
            V++D VE +DG FF    GEE++Q  +KM+KSLKN V PDD+ +++GADTLRVYEM MGP
Sbjct  583  VATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGP  642

Query  755  LDTSRPWATKDVVGAQRFLQRLWRLVVDENTGEVLTRDEVLTDDDNKQLHRTIAGVRDDY  814
            LD+S +W+  ++ G+++FL+R+ RL+   +  E       L    +K  + T+ +V ++ 
Sbjct  643  LDASIAWSEEGLEGSRKFLDRVYRLITTKEITE--ENSGAL----DKVYNETVKAVTEQV  696

Query  815  TNLRVNTVVAKLIEYVNYLTKTYPDTIPAGAVLPLIVMVSPVAPHIAEELWKKL-GHDDT  873
             +++ NT +A+L+ +VN   K   D + ++    ++ +++P APH++EELW+ L + +++
Sbjct  697  DQMKFNTAIAQLMVFVNAANKE--DKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGES  754

Query  874  VTYEPFPTFEEKWLTDDEIELPVQVNGKVRGRITVAADASQEQVIEAALADEKVQEQISG  933
            ++Y P P+++E  L ++++E+ VQ++GKV++++ VA D S+E++ E ALA+EKVQ +I+G
Sbjct  755  ISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAG  814

Query  934  KNLIKQIVVPGRMVNLVVK  952
            K++IK I VP ++VN+V+K
Sbjct  815  KDIIKVIAVPNKLVNIVIK  833


 Score =  141 bits (519),  Expect = 2e-34, Method: Compositional matrix adjust.
 Identities = 79/149 (54%), Positives = 104/149 (70%), Gaps = 11/149 (7%)

Query  23   IEGEWQNYWTDNGTFNAPNPVGDLAPADGKALPEDKLFVQDMFPYPSGAGLHVGHPLGYI  82
            IE  WQ +W+DN TF++           G   +  K++  DMFPYPSGAGLHVGHP GY 
Sbjct  9    IEPKWQAFWADNHTFKT-----------GTDASKPKFYALDMFPYPSGAGLHVGHPEGYT  57

Query  83   ATDVFARYNRMLGKNVLHTLGYDAFGLPAEQYAIQTGTHPRTTTMANIENMKRQLGALGL  142
            ATD+++R++R  G NVLH +G DAFGLPAEQYA++TG +P   T  NI N KRQ+ ALG+
Sbjct  58   ATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGF  117

Query  143  GHDSRRAVATTDPEFYKWTQWIFLQIFNS  171
            + D  R V TTDP++YKWTQWIF ++++ 
Sbjct  118  SYDWDREVNTTDPNYYKWTQWIFTKLYEK  146

978) leuS in NC_021352


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  552 bits (2083),  Expect = 5e-158, Method: Compositional matrix adjust.
 Identities = 356/739 (49%), Positives = 504/739 (69%), Gaps = 59/739 (7%)

Query  220  LVYRSNSTVNWCPGLGTVLANEEVTADGRSERGNFPVFRKNLSQWMMRITAYSDRLIDDL  279
            L Y ++  VNW   LGT +ANEEV +DG SERG +PV RK + QWM++ITAY++RL++DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  280  ELLDWTEKVKSMQRNWIGRSRGAEVDFSAE--GETVTVFTTRPDTLFGATYMVLAPEHEL  337
            E +DW E +K MQRNWIG+S GA+V F     +   TVFTTRPDTLFGATY VLAPEH L
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  338  VDVLLEKAGSYEGVDARWTNGQASPAEAVAAYRASIAAKSDLERQE-NKEKTGVFLGVYA  396
            VD +                  +  AEAVA Y+   + KSDL R +  KEKTGV  G YA
Sbjct  268  VDAI----------------TTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYA  311

Query  397  TNPVNGDQIPVFIADYVLTGYGTGAIMTVPAHDERDYEFATVLGLPIKEVVAGGNIEEAA  456
             NPVNG ++PV IADYVL++YGTGAIM+VPAHDERD EFA  + L I  V+ GGN+EEAA
Sbjct  312  INPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEAA  371

Query  457  FTESGEAVNSANDNGLDINGLAKDEAVAKTIEWLEEKELGRGTIQYKLRDWLFARQRYWG  516
            FTE G  +NS       ++GL K  A+AK +EWLE   +G   + Y+LRDWLF+RQRYWG
Sbjct  372  FTEDGLHINSDF-----LDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWG  426

Query  517  EPFPIVYDENGQAHALPDSMLPVELPEVEDYKPVSFdpedadsepsppLAKAREWVEVEL  576
            EP+PI+  E+G + A+P+S LP+ LP   D +P +           +PLA+  +W+EV  
Sbjct  427  EPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSG--------TGESPLANVTDWLEVTR  478

Query  577  DLGDGKKKYTRDTNVMPQWAGSSWYQLRYVDPSNDEQFCNIENERYWTGPRPETHGPNDP  636
            +  DG K   R+TN MPQWAGSSWY LRY+DP N E++ + E  + W             
Sbjct  479  E--DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWL------------  523

Query  637  GGVDLYVGGVEHAVLHLLYARFWHKVLFDLGHVSSKEPYRRLYNQGYIQAFAYTDSRGVY  696
              VD+YVGG EHAVLHLLYARFWHKVL+DLG V++KEP+++L+NQG I + +Y DSRG  
Sbjct  524  -PVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGAL  582

Query  697  VPADDVEEKDGKFFY--QGEEVNQEYGKMGKSLKNAVAPDDICNNFGADTLRVYEMAMGP  754
            V++D VE +DG FF    GEE++Q  +KM+KSLKN V PDD+ +++GADTLRVYEM MGP
Sbjct  583  VATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGP  642

Query  755  LDTSRPWATKDVVGAQRFLQRLWRLVVDENTGEVLTRDEVLTDDDNKQLHRTIAGVRDDY  814
            LD+S +W+  ++ G+++FL+R+ RL+   +  E       L    +K  + T+ +V ++ 
Sbjct  643  LDASIAWSEEGLEGSRKFLDRVYRLITTKEITE--ENSGAL----DKVYNETVKAVTEQV  696

Query  815  TNLRVNTVVAKLIEYVNYLTKTYPDTIPAGAVLPLIVMVSPVAPHIAEELWKKL-GHDDT  873
             +++ NT +A+L+ +VN   K   D + ++    ++ +++P APH++EELW+ L + +++
Sbjct  697  DQMKFNTAIAQLMVFVNAANKE--DKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGES  754

Query  874  VTYEPFPTFEEKWLTDDEIELPVQVNGKVRGRITVAADASQEQVIEAALADEKVQEQISG  933
            ++Y P P+++E  L ++++E+ VQ++GKV++++ VA D S+E++ E ALA+EKVQ +I+G
Sbjct  755  ISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAG  814

Query  934  KNLIKQIVVPGRMVNLVVK  952
            K++IK I VP ++VN+V+K
Sbjct  815  KDIIKVIAVPNKLVNIVIK  833


 Score =  141 bits (519),  Expect = 2e-34, Method: Compositional matrix adjust.
 Identities = 79/149 (54%), Positives = 104/149 (70%), Gaps = 11/149 (7%)

Query  23   IEGEWQNYWTDNGTFNAPNPVGDLAPADGKALPEDKLFVQDMFPYPSGAGLHVGHPLGYI  82
            IE  WQ +W+DN TF++           G   +  K++  DMFPYPSGAGLHVGHP GY 
Sbjct  9    IEPKWQAFWADNHTFKT-----------GTDASKPKFYALDMFPYPSGAGLHVGHPEGYT  57

Query  83   ATDVFARYNRMLGKNVLHTLGYDAFGLPAEQYAIQTGTHPRTTTMANIENMKRQLGALGL  142
            ATD+++R++R  G NVLH +G DAFGLPAEQYA++TG +P   T  NI N KRQ+ ALG+
Sbjct  58   ATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGF  117

Query  143  GHDSRRAVATTDPEFYKWTQWIFLQIFNS  171
            + D  R V TTDP++YKWTQWIF ++++ 
Sbjct  118  SYDWDREVNTTDPNYYKWTQWIFTKLYEK  146

979) leuS in NC_021521


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  552 bits (2083),  Expect = 5e-158, Method: Compositional matrix adjust.
 Identities = 371/866 (43%), Positives = 567/866 (66%), Gaps = 46/866 (5%)

Query  5    YNPSAIEPKVQQYWAENKVFKAIKDESKPKYYCLSMFPYPSGR-LHMGHVRNYTIGDVVS  63
            Y+ +AIEPK Q +WA+N  FK+  D SKPK+Y L MFPYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMNGKNVLQPMGWDAFGLPAEGAAVKNKTAPAKWTYENIEYMKNQLKALGFGFDWDR  123
            R++R +G NVL+PMGWDAFGLPAE  A+     PA  T ENI   K Q++ALGF++DWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVTTCRPEYYKWEQWFFTELYKKGLVYKKTSTVNWCPNDETVLANEQV-HEGCCWRCDTP  182
            EV T  P+YYKW QW+FT LY KGL Y     VNW  +  T +ANE+V  +G   R + P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VEQKEIPQWFIKITDYAEQLLNDLDRLPLWPDQVKTMQRNWIGRSEGVEITFKVKGTDQT  242
            V +K + QW +KIT YAE+LL+DL+ +  WP+ +K MQRNWIG+S G ++TFKVK+TD+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LPVYTTRPDTFFGVSYv--avaaahplatlaaENNPALAAFIQEAK-NTKVAEADIATME  299
            + V+TTRPDT+FG +Y   A   A   A  ++++  A+A + ++A  ++ +A +D+A  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGMATGLFAIHPLTGEEVPVWVANFVLMHYGTGAVMAVPAHDERDFEFAQKYNLPIKQV  359
            K G+ TG +AI+P+ G E+PVW+A++VL  YGTGA+MAVPAHDERD EFA+++NL   ++
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNL---DI  358

Query  360  IAPLDGSEWDFSKAAMTEHGKLINSAEFDGLDFDGAFKGIADKLEGMGIGKRQVNYRLRD  419
            I+ L+G+  +   AA TE+G  INS  +DGLD  +A+  + + LE+ G+G+ +V YRLRD
Sbjct  359  IPVLEGG--NVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMLTLENGETVTVPMQDLPVVLP--EDVVMDGV-KSPIKADPEWAKT  476
            W  SRQRYWG PIP++  E+G + +VP  +LP+VLP   D+   G   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  TY-NGQPALRETDTFDTFMESSWYYARYASPQYQQGMLDKEEANYWLPVDQYIGGIEHAT  535
            T  +G  + RET+T      SSWYY RY  P+  + + D E  + WLPVD Y+GG EHA 
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLLYFRFFHKLLRDAGFVTSDEPTEKLLCQGMVLADAYYYTSPTNERIWVSPTEVTVER  595
            +HLLY RF HK+L D G V + EP +KL+ QGM+L+ +Y      + R     + V+ ++
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSR----GALVATDK  587

Query  596  DEKGRILKAFDKEGRALVHSGMTKMSKSKNNGIDPQEMVEKYGADTVRLFMMFASPAEMT  655
             EK R    F+ E    ++ + +KMSKS +N ++P+++VE+YGADT+R++ MF +P + +
Sbjct  588  VEK-RDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  656  LEWQESGVEGAKRFLGRLWNLAYEYAQSPATVALDPTALSKEQKDLRRDVHKTIAKVSDD  715
            + W E G+EG+++FL+R+    Y    +      ++ AL K  ++       T+  V+++
Sbjct  647  IAWSEEGLEGSRKFLDRV----YRLITTKEITEENSGALDKVYNE-------TVKAVTEQ  695

Query  716  IGRRQTFNTAIAAIMELMNKLTKAPLVNDQDKAVMAEALNAVIRMLYPITPHICFELWQA  775
            +++ + FNTAIA +M ++N         +++  + ++  ++ ++++ P++PH+  ELWQA
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  776  LGNEG-SIDFAPWVVADEKAMVEDEKLVVVQVNGKVRGKITVSATATEGEVKAIAKADEN  834
            L   G SI + PW   DE  +VE++  +VVQ++GKV++K+ V+   +  E++ +A A+E+
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  835  VAKYLEGVEIVKEIYVPFKMLSFAVK  860
            V   + G +I+K I VP K++++ +K
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVIK  833

980) leuS in NC_008345


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  552 bits (2082),  Expect = 5e-158, Method: Compositional matrix adjust.
 Identities = 366/873 (42%), Positives = 557/873 (64%), Gaps = 55/873 (6%)

Query  13   LYNPSEIEALVQKHWHEHKTFEVTEDESKEKFYCLSMFPYPSGR-LHMGHVRNYTIGDVV  71
            +Y+ + IE+  Q  W ++ TF    D SK KFY L MFPYPSG  LH+GH   YT  D++
Sbjct  3    FYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDIL  62

Query  72   ARYQRLQGKNVLQPIGWDSFGLPAENAAINNKASPAPWTYENIDYMKNQLKLLGFGYDWS  131
            +R++R QG NVL+P+GWD+FGLPAE+ A++    PA  T ENI   K Q++ LGF+YDW 
Sbjct  63   SRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWD  122

Query  132  REIATCTPEYYRWEQWFFTQLYAKGLVYKKTSSVNWCPNDETVLANEQV-QDGCCWRCDT  190
            RE+ T  P+YY+W QW+FT+LY KGL Y    +VNW  +  T +ANE+V  DG   R + 
Sbjct  123  REVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGY  182

Query  191  EVIQKEIPQWFIKITDYAEELLNDIDTLDGWPEQVKAMQRNWIGRSEGIEMTFAVADSDA  250
             V++K + QW +KIT YAE LL+D++ +D WPE +K MQRNWIG+S G ++TF V D+D 
Sbjct  183  PVVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDK  241

Query  251  SFDIYTTRPDTLMGVTYVAIAAGHPLAEQSAQNNPELAAFLEECKNADTTEAAMA----S  306
             F ++TTRPDTL G TY  +A+ H+L +  A   ++ A  + + K   +  + +A    +
Sbjct  242  DFTVFTTRPDTLFGATYAVLAPEHALVD--AITTSDQAEAVADYKRQASLKSDLARTDLA  299

Query  307  MEKKGVATGLQAIHPISGKLVPIWVANFVLMNYGTGAVMSVPAHDQRDYEFATKYQLAIE  366
             EK GV TG  AI+P++GK +P+W+A++VL +YGTGA+M+VPAHD+RD EFA +++L I 
Sbjct  300  KEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDII  359

Query  367  AVIKPVDGEVDVSKEAYTEKGVVFNSGDAFPELDGLDFQAAFEAIDARLTAEGKGKRQVN  426
            +V+       +V   A+TE G+ +NS+  F  LDGLD  +A+  +  +L AEG G+ +V 
Sbjct  360  PVL----EGGNVEEAAFTEDGLHINSD--F--LDGLDKASAIAKMVEWLEAEGVGNENVT  411

Query  427  YRLRDWGVSRQRYWGAPIPMVTLADGTVVPTPEDQLPVILP--EDVVMDGI-QSPIKADK  483
            YRLRDW  SRQRYWG PIP++   DGT  + PE +LP++LP   D+   G  +SP+    
Sbjct  412  YRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVT  471

Query  484  AWAETT-VNGQPATRETDTFDTFMESSWYYARYCSPHADEML-DPAKANYWLPVDQYIGG  541
             W E T  +G  + RET+T      SSWYY RY  PH  E L D    + WLPVD Y+GG
Sbjct  472  DWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGG  531

Query  542  IEHACMHLLYFRFFHKLLRDAGLVNSDEPAKQLLTQGMVLADAYYYTNEKGARVWVSPLE  601
             EHA +HLLY RF HK+L D G+V + EP ++L+ QGM+L+ +  Y + +GA V      
Sbjct  532  AEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS--YRDSRGALV-----A  584

Query  602  VTVVEKDDKGRIIKAIDNQGHELVYTGMSKMSKSKNNGIDPQVMVEKYGADTVRLFMMFA  661
               VEK D G ++    + G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF 
Sbjct  585  TDKVEKRD-GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFM  640

Query  662  SPPELTLEWQESGVEGAHRFIKR-FWKLASDHVAAGKTEALDTSKLNADQKALRRELHKT  720
            +P + ++ W E G+EG+++F+ R ++ +++ +++  ++ ALD            +  + T
Sbjct  641  GPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALD------------KVYNET  688

Query  721  IAKVSDDIARRQMFNTAVASVMELMNHLLKASQETAQDRALLAEALSAVTRLLYPIVPHM  780
            +  V++++ + + FNTA+A +M ++N        + ++  L+++   +  +L+ P+ PH+
Sbjct  689  VKAVTEQVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHL  740

Query  781  TFTLWNELGNEGD-IEDSRWPEVDESALVEDSKLIVVQVNGKVRAKITVAADASKEDVEA  839
               LW+ L   G+ I    WP  DES LVE+   IVVQ++GKV+AK+ VA D S+E+++ 
Sbjct  741  GEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQE  800

Query  840  LGMSDEHVQKHTEGLTVRKVIYVPGKLLSIVAN  872
            +++++E VQ +  G  + KVI VP KL++IV +
Sbjct  801  VALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

981) leuS in NC_010506


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  552 bits (2082),  Expect = 5e-158, Method: Compositional matrix adjust.
 Identities = 358/866 (42%), Positives = 557/866 (65%), Gaps = 47/866 (5%)

Query  5    YQPSEIEAKVQQHWQDTKTFEVTEDENKEKFYCLSMFPYPSGR-LHMGHVRNYTIGDVVA  63
            Y+ + IE+K Q  W D  TF    D +K KFY L MFPYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRLQGKNVLQPIGWDSFGLPAENAAIKNSSAPAPWTYENIDYMKNQLKMLGFGYDWSR  123
            R++R QG NVL+P+GWD+FGLPAE+ A+  ++ PA  T ENI   K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EIATCTPEYYRWEQWFFTKLYEKGLVYKKTASVNWCPNDETVLANEQV-QDGCCWRCDTE  182
            E+ T  P+YY+W QW+FTKLYEKGL Y    +VNW  +  T +ANE+V  DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VVQKEIPQWFIKITDYADELLSDIDQLDEWPEQVKTMQRNWIGRSEGIEMTFQVADSDES  242
            VV+K + QW +KIT YA+ LL D++++D WPE +K MQRNWIG+S G ++TF+V D+D  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  FDIYTTRPDTVMGVTYVAIAAGHPLAE--KAAANSPELAAFIEECKNADtteaamaamek  300
            F ++TTRPDT+ G TY  +A+ H+L +   ++ ++  +A +  +         +  A EK
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEK  302

Query  301  kGVATGLYAIHPLTGKQVPIWAANFVLMNYGTGAVMSVPAHDQRDYEFAIKYGLAIEGVI  360
             GV TG YAI+P+ GK++P+W A++VL +YGTGA+M+VPAHD+RD EFA ++ L I  V+
Sbjct  303  TGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL  362

Query  361  KPEDAELDISEEAYTEKGVLFNSAEFDGLDFQAAFDAIDAKLTAEGKGKRQVNFRLRDWG  420
               + E    E A+TE G+ +NS  +DGLD  +A+  +   L AEG G+ +V +RLRDW 
Sbjct  363  EGGNVE----EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWL  418

Query  421  VSRQRYWGAPIPMVTLADGTVVPTPEDQLPVILP--EDVVMDGI-QSPIKADKEWAK-TQ  476
             SRQRYWG PIP++   DGT  + PE +LP++LP   D+   G  +SP+    +W   T+
Sbjct  419  FSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTR  478

Query  477  INGEDALRETDTFDTFMESSWYYARYCSPHADEML-DPAKANYWLPVDQYIGGIEHACMH  535
             +G  + RET+T      SSWYY RY  PH  E L D    + WLPVD Y+GG EHA +H
Sbjct  479  EDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLH  538

Query  536  LLYFRFFHKLLRDIGLVNSDEPAKRLLTQGMVLADAYYYTNEKGARVWVSPADVTVQETD  595
            LLY RF HK+L D+G+V + EP ++L+ QGM+L+ +Y     +++R     A V+ +  +
Sbjct  539  LLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSR----GALVATDKVE  589

Query  596  DKGRTVKAVDSHGNELVYTGMSKMSKSKNNGIDPQEMVDKYGADTVRLFMMFAAPPELTL  655
             ++ +   V++ G+EL   + +KMSKS +N ++P+++V++YGADT+R++ MF +P + ++
Sbjct  590  KRDGSFFHVET-GEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASI  647

Query  656  EWQESSVEGAHRFIKRLWK-VAHDHVAKGTTVSLDVKSLDAKQKELRRELHKTIAKVGDD  714
             W E ++EG+++F+ R+ + ++  +++   + +LD            +  + T+  V ++
Sbjct  648  AWSEEGLEGSRKFLDRVYRLITTKEITEENSGALD------------KVYNETVKAVTEQ  695

Query  715  IERRQMFNTAIASVMELMNRLQKAPTETEQDRALMQEALSAVVRLLYPIIPHTSFSLWKE  774
            +++ + FNTAIA +M ++N        ++++  L  +   + V+L+ P+ PH +  LW+ 
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  775  L-GNEENIEDVRWPEADESALVEDSKLIIVQVNGKLRAKITVPADATKEAVEAQGFAEEG  833
            L ++ E+I  V WP  DES LVE+   I+VQ++GK++AK+ V+ D ++E ++  ++A+E 
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  834  VIKHTEGKTVRKVIYVPGKLLNIVAN  859
            V  +  GK + KVI VP KL+NIV +
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVIK  833

982) leuS in NC_010159


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  552 bits (2082),  Expect = 5e-158, Method: Compositional matrix adjust.
 Identities = 357/866 (42%), Positives = 552/866 (64%), Gaps = 48/866 (5%)

Query  5    YRPEDIETQVQLHWQEKQTFKVTEDASKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIS  63
            Y    IE + Q  W +++TFK   DASK K+Y L M+PYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIEYMKNQLKLLGFGYDWDR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NI   K Q++ LGF+YDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EIATCKPDYYRWEQWFFTKLYEKGMVYKKTSAVNWCPHDLTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W QW+FTKLYEKG+ Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITDYAEQLLNDLDTLESWPEQVKTMQRNWIGRSEGVDIVFDVVDSEEK  242
            V RK + QW +KIT YAE+LL+DL+ ++ WPE +K MQRNWIG+S G ++ F V D++  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LSVYTTRPDTFMGVTYVAVAAGHPLSLQAAATNPALADFVAECRNTKVAEAEMA----TM  298
            ++V+TTRPDT+ G TY  +A+ H+L    A T +  A+ VA+ +      +++A    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALV--DAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  299  EKKGMATGLYAIHPLTGEKLPIWAANFVLMDYGTGAVMAVPGHDARDWEFATKYNLPIKP  358
            EK G+ TG YAI+P+ G  +P+W A++VL  YGTGA+MAVP+HD RDWEFA ++NL I P
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VILAADGSEPDLSQEAMTEKGTLFNSGEFDGLNHEDGFNAIADKLVALGVGQRKVNYRLR  418
            V+ +++  E+ ++++++  ++ +     +DGL+   ++  + + L A GVG+ +V YRLR
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDF-----LDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  419  DWGVSRQRYWGAPIPMVTLEDGTVVPTPEDQLPVILP--EDVVMDGIS-SPIKADPEWAK  475
            DW  SRQRYWG PIP++  EDGT  + PE +LP++LP   D+   G + SP+    +W  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  476  TT-VNGIPGLRETDTFDTFMESSWYYARYTCPQYDDGMLDPAAANYWLPVDQYVGGIEHA  534
             T  +G+ G RET+T      SSWYY RY  P+  + + D    + WLPVD YVGG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  535  IMHLMYFRFFHKLLRDAGLVDSDEPAKRLLCQGMVLADAFYYTGNNGERIWVSPVDAIVE  594
            ++HL+Y RF HK+L D G+V + EP ++L+ QGM+L+ +  Y ++ G    + + D +  
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS--YRDSRGA---LVATDKVEK  590

Query  595  RDDKGRIVKAVDAEGHELVYAGMSKMSKSKNNGIDPQVMVEKYGADTVRLFMMFASPAEM  654
            RD  G +     +E  E    + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P + 
Sbjct  591  RD--GSFFHVETGEELE---QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  655  TLEWQESGVEGANRFLKRVWRLAFDHTAKGAVKPLDIASLTEEQKSLRRDLHKTIAKVTD  714
            ++ W E G+EG+ +FL RV RL         +   +I+   E+  +L +  + T+  VT+
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRL---------ITTKEITE--ENSGALDKVYNETVKAVTE  694

Query  715  DVGRRQTFNTAIAAVMELMNKLGRAPQETEQDRALMQEALLAVVRMLYPFTPHVCFSLWQ  774
            +V++ + FNTAIA +M ++N        ++++  L  +   + V+++ PF+PH+   LWQ
Sbjct  695  QVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  775  ALGGEGD-IDTAPWPIADEQAMVEDSKLVVVQVNGKVRGRITVPADATEQQVRERAGQEH  833
            AL + G+ I   PWP  DE  +VE+   +VVQ++GKV++++ V+ D + ++++E A  ++
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  834  LVAKYLDGITVRKVIYVPGKLLNLVV  859
             V   + G  + KVI VP KL+N+V+
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVI  832

983) leuS in NC_004342


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  551 bits (2078),  Expect = 1e-157, Method: Compositional matrix adjust.
 Identities = 352/703 (51%), Positives = 481/703 (69%), Gaps = 57/703 (8%)

Query  199  LVYQAEIPVNWCEALGTVLANEEV---EEWVGKGYEVVRKPMRQYMMRITAYADRLLEDL  255
            L Y+AE+PVNW E LGT +ANEEV         GY VVRKPMRQ M++ITAYA+RLLEDL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  256  ELVEWPPSTLEMQKNWIGKSEGLEITFPFLKPLQSGLEGIRIFTTRPDTIFGVTYMVVAP  315
            E V+WP S  +MQ+NWIGKS G ++TF     ++    ++ +FTTRPDT+FG TY V+AP
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFK----VKDTDKDFTVFTTRPDTLFGATYAVLAP  263

Query  316  EHPIVSEITTPEQKQKVEEYQKTSSLKSDLDRMELNKEKTGVFTGTFVFNPADPSQKIPV  375
            EH++V  ITT++Q + V +Y++ +SLKSDL R +L KEKTGV TG++ +NP +  + +PV
Sbjct  264  EHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAINPVNGKE-MPV  322

Query  376  WISDYVLYGYGTGAIMAVPAHDQRDFEFARTFGLKIIPVIEG-EISEAAFDsktstcins  434
            WI+DYVL +YGTGAIMAVPAHD+RD EFA+ F L IIPV+EG ++ EAAF        + 
Sbjct  323  WIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEAAFTEDGLHINSD  382

Query  435  ssseisinGLDYTSASSKIISWAESKKIGRKKIQFKLRDWLFARQRYWGEPIPLVHYPSG  494
                    GLD +SA +K++ W E+  +G  ++ ++LRDWLF+RQRYWGEPIP++H   G
Sbjct  383  FLD-----GLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDG  437

Query  495  VTKPIPESELPLVLPNLEEFKPSGTGESPLALAKDWLQYKDPSTGEIGTRETNTMPQWAG  554
             + ++PESELPLVLP   +++PSGTGESPLA   DWL+      G  G RETNTMPQWAG
Sbjct  438  TSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT-REDGVKGRRETNTMPQWAG  496

Query  555  SCWYYLRYIDPKNGRFLCDPELEKKWMPVNLYVGGSEHAVLHLLYSRFWHKFLFDIGAVS  614
            S WYYLRYIDP N   L D EL K+W+PV++YVGG+EHAVLHLLY+RFWHK L+D+G V+
Sbjct  497  SSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVP  556

Query  615  TKEPFDKLIHQGLILGE---------------DKR------------------KMSKSLG  641
            TKEPF+KL++QG+ILG                +KR                  KMSKSL 
Sbjct  557  TKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLK  616

Query  642  NVVNPDDVIKEYGADSLRLFEMFMGPLEMVKPWSTRGVEGVFRFLNRIWRLFHSGSQESF  701
            NVVNPDDV+ +YGAD+LR++EMFMGPL+   +WS  G+EG  +FL+R+ RL+ +      
Sbjct  617  NVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTK-----  671

Query  702  RLDDVEPTPEEL-KILHKTIQKVNEDIPNFSFNTAIAQLMIFVNEFTPSDRRPKKVLESF  760
              +  E  +  L K+ + T++ V E++ +  FNTAIAQLM+FVN     D+       +F
Sbjct  672  --EITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGF  729

Query  761  ILLLAPFAPHIAEELWKR-SGKMESLSYEKFPEADPQYLIESEILIVVQVNGKLRDEFKA  819
            + L+APFAPH++EELW+  ++  ES+SY   P  D   L+E+++ IVVQ++GK++  +  
Sbjct  730  VQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVV  789

Query  820  PKDVSQSDAISMAKNLDKIKGILEGKTIRKEIYVPGKLVNLVI  862
            +KD+S+ +   +A   +K+++ + GK I K I VP KLVN+VI
Sbjct  790  AKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832


 Score =  186 bits (690),  Expect = 5e-48, Method: Compositional matrix adjust.
 Identities = 97/142 (69%), Positives = 119/142 (84%), Gaps = 0/142 (0%)

Query  3    YPFQEVESFWQKFWEEHKSFQTNIRSSKPKFYCLDMFPYPSGAGLHVGHPEGYTATDILS  62
            Y    +E+ WQ FW ++ +F+T   +SKPKFY LDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RFKRMKGFEVLHPMGWDAFGLPAERYAMQTGIHPAITTKDNIDNFRRQIQMIGLSYDWSR  122
            RFKR +G +VLHPMGWDAFGLPAE+YAM+TG +PA  T +NI NF+RQI+ +G+SYDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  ELSTTDPDYYKFTQWIFIQLYQ  144
            E++TTDP+YYK TQWIF +LY+
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYE  145

984) leuS in NC_017551


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  551 bits (2078),  Expect = 1e-157, Method: Compositional matrix adjust.
 Identities = 352/703 (51%), Positives = 481/703 (69%), Gaps = 57/703 (8%)

Query  199  LVYQAEIPVNWCEALGTVLANEEV---EEWVGKGYEVVRKPMRQYMMRITAYADRLLEDL  255
            L Y+AE+PVNW E LGT +ANEEV         GY VVRKPMRQ M++ITAYA+RLLEDL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  256  ELVEWPPSTLEMQKNWIGKSEGLEITFPFLKPLQSGLEGIRIFTTRPDTIFGVTYMVVAP  315
            E V+WP S  +MQ+NWIGKS G ++TF     ++    ++ +FTTRPDT+FG TY V+AP
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFK----VKDTDKDFTVFTTRPDTLFGATYAVLAP  263

Query  316  EHPIVSEITTPEQKQKVEEYQKTSSLKSDLDRMELNKEKTGVFTGTFVFNPADPSQKIPV  375
            EH++V  ITT++Q + V +Y++ +SLKSDL R +L KEKTGV TG++ +NP +  + +PV
Sbjct  264  EHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAINPVNGKE-MPV  322

Query  376  WISDYVLYGYGTGAIMAVPAHDQRDFEFARTFGLKIIPVIEG-EISEAAFDsktstcins  434
            WI+DYVL +YGTGAIMAVPAHD+RD EFA+ F L IIPV+EG ++ EAAF        + 
Sbjct  323  WIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEAAFTEDGLHINSD  382

Query  435  ssseisinGLDYTSASSKIISWAESKKIGRKKIQFKLRDWLFARQRYWGEPIPLVHYPSG  494
                    GLD +SA +K++ W E+  +G  ++ ++LRDWLF+RQRYWGEPIP++H   G
Sbjct  383  FLD-----GLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDG  437

Query  495  VTKPIPESELPLVLPNLEEFKPSGTGESPLALAKDWLQYKDPSTGEIGTRETNTMPQWAG  554
             + ++PESELPLVLP   +++PSGTGESPLA   DWL+      G  G RETNTMPQWAG
Sbjct  438  TSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT-REDGVKGRRETNTMPQWAG  496

Query  555  SCWYYLRYIDPKNGRFLCDPELEKKWMPVNLYVGGSEHAVLHLLYSRFWHKFLFDIGAVS  614
            S WYYLRYIDP N   L D EL K+W+PV++YVGG+EHAVLHLLY+RFWHK L+D+G V+
Sbjct  497  SSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVP  556

Query  615  TKEPFDKLIHQGLILGE---------------DKR------------------KMSKSLG  641
            TKEPF+KL++QG+ILG                +KR                  KMSKSL 
Sbjct  557  TKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLK  616

Query  642  NVVNPDDVIKEYGADSLRLFEMFMGPLEMVKPWSTRGVEGVFRFLNRIWRLFHSGSQESF  701
            NVVNPDDV+ +YGAD+LR++EMFMGPL+   +WS  G+EG  +FL+R+ RL+ +      
Sbjct  617  NVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTK-----  671

Query  702  RLDDVEPTPEEL-KILHKTIQKVNEDIPNFSFNTAIAQLMIFVNEFTPSDRRPKKVLESF  760
              +  E  +  L K+ + T++ V E++ +  FNTAIAQLM+FVN     D+       +F
Sbjct  672  --EITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGF  729

Query  761  ILLLAPFAPHIAEELWKR-SGKMESLSYEKFPEADPQYLIESEILIVVQVNGKLRDEFKA  819
            + L+APFAPH++EELW+  ++  ES+SY   P  D   L+E+++ IVVQ++GK++  +  
Sbjct  730  VQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVV  789

Query  820  PKDVSQSDAISMAKNLDKIKGILEGKTIRKEIYVPGKLVNLVI  862
            +KD+S+ +   +A   +K+++ + GK I K I VP KLVN+VI
Sbjct  790  AKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832


 Score =  186 bits (690),  Expect = 5e-48, Method: Compositional matrix adjust.
 Identities = 97/142 (69%), Positives = 119/142 (84%), Gaps = 0/142 (0%)

Query  3    YPFQEVESFWQKFWEEHKSFQTNIRSSKPKFYCLDMFPYPSGAGLHVGHPEGYTATDILS  62
            Y    +E+ WQ FW ++ +F+T   +SKPKFY LDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RFKRMKGFEVLHPMGWDAFGLPAERYAMQTGIHPAITTKDNIDNFRRQIQMIGLSYDWSR  122
            RFKR +G +VLHPMGWDAFGLPAE+YAM+TG +PA  T +NI NF+RQI+ +G+SYDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  ELSTTDPDYYKFTQWIFIQLYQ  144
            E++TTDP+YYK TQWIF +LY+
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYE  145

985) leuS in NC_013552


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  551 bits (2078),  Expect = 1e-157, Method: Compositional matrix adjust.
 Identities = 355/849 (42%), Positives = 541/849 (64%), Gaps = 59/849 (6%)

Query  5    YNPQETEKKWQDKWAADRLYHASEDSPKPKWYSLTMFPYTSG-NLHIGHWYAEVPADCFA  63
            Y+    E KWQ  WA ++ + ++ D++KPK Y+L MFPY SG  LH+GH  +  ++D ++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYKRLNGFNVMRPVGFDSFGLPAENAAIKHHIHPRIWTLNNVENMRRQLKTIGAMFDWDR  123
            R+KR +G NV++P+G D+FGLPAE+ A+    +P   T +N+ N +RQ++++G  +DWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVITCLPEYYKWTQWFFLKLYEAGLAYRAKAPVNWCPSCQAVLANEQVV-DGTCWRCETP  182
            EV T  P+YYKWTQW+F KLYE GLAY A  PVNW     + +ANE+V+ DGT  R   P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  TTRRDLEQWFFRITNYADEL-KDHEGLDWPEKITAMQRNWVGKSYGAEVSFALDCPAAPE  241
              R+ + QW ++IT YA+ L  D E +DWPE I  MQRNW+GKS GA+V+F +      +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVK---DTD  240

Query  242  QEIKVFTTRPDTIYGVTFMVLAPEHSLVEKITTPENKAAVDEYIKKSRACTEIERLSTER  301
            +++ VFTTRPDT++G T+ VLAPEH+LV+ ITT+++  AV +Y +++   +++ R    +
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  302  EKDGVFTGAYVTNRVNGHKVPVWIGDYVLQSYGTGAVMGVPAHDERDFVFAQKYHLPVIT  361
            EK GV TG+Y  N VNG  +PVWI+DYVL SYGTGA+M+VPAHDERD  FA++++L +I 
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  362  VIAPPDYDGQPLEAAYINEGVMQNSGPFNGLPNTEGKEKVSDYLAEHGWGKKTVNYKLRD  421
            V+     +G+  EAA+ ++G+  NS+ ++GL ++ +  K+ + L  +G G+  V Y+LRD
Sbjct  361  VLE----GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  422  WLISRQRYWGAPIPMVYCEKCGIVPVPEKDLPVLLPEDVEFRSG--GESPLKYNEGFVNT  479
            WL+SRQRYWG PIP++  E     +VPE +LP++LP   ++R++  GESPL    + ++ 
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  480  TCPVCGGKAKRETDTMDTFMCSSWYFLRYTSPGYDKGPFDPEKLRYWMPVDLYTGGAEHA  539
            T    G K++RET+TM     SSWY+LRY  P       D E L+ W+PVD+Y GGAEHA
Sbjct  477  TRE-DGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  540  VMHLFYSRFFTKALRDMGIIDFGEPFKKLFNQGIIVSN----------------------  577
            V+HL+Y+RF  K L D+G++   EPF+KLFNQG+I++                       
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSF  595

Query  578  ------------HQKMSKSKGNVVTPDNLVAEVGTDAVRAYLMFVGPWDQGGEWNDSGLS  625
                          KMSKS  NVV PD++V + G+D++R Y MF+GP D +  W++ GL 
Sbjct  596  FHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLE  655

Query  626  GMSRWLNRVWNLFTEEYTPKTASAEAERELKRTLHQTIKKITMDIERLRFNTVVAALMEL  685
            G  + L+RV  L+    T K  + E    L +  ++T+K +T ++++++FNT +A LM  
Sbjct  656  GSRKFLDRVYRLI----TTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMV-  710

Query  686  SNSLAKFKEAAAISAESWQNSLKTFALMLAPIAPHIAEELWANL-GMEYSIHNQSWPKWD  744
                  F +AA        +  K F  ++AP+APH++EELW  L +   SI   +WP  D
Sbjct  711  ------FVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYD  764

Query  745  EELAKDEVITLIIQVNGKLRERLEMPAGISEDEAKETALNSARVKPHLQGKTPASVIYVP  804
            E    ++ + +++Q++GK++ +L ++ ++S +E +E AL + +V++++ GK    VI VP
Sbjct  765  ESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVP  824

Query  805  GKLVNIVVK  813
             KLVNIV+K
Sbjct  825  NKLVNIVIK  833

986) leuS in NC_008245


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  551 bits (2081),  Expect = 5e-158, Method: Compositional matrix adjust.
 Identities = 355/856 (42%), Positives = 552/856 (65%), Gaps = 72/856 (8%)

Query  4    YNFSDIEKSTQEYWRKNDTFKTIEDNTKEKFYCLSMLPYPSGT-LHMGHVRNYTIGDVIA  62
            Y+ + IE   Q +W  N+TFKT  D +K KFY L M+PYPSG+ LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYQKMQGKNVLHPMGWDAFGLPAENAAIKHKKSPYEWTKSNIAYMRSQFDSLGFSFDWSR  122
            R+++ QG NVLHPMGWDAFGLPAE+ A+   + P E T  NIA  + Q+++LGFS+DW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EITTCDEDYYKWEQWFFIQLYKKGLAYRKNSVVNW-DPVDQTVLANEQVVDGRGWRSGAL  181
            E+ T D +YYKW QW+F +LY KGLAY  +  VNW + ++ ++  +E + DG + R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VEKKEIPQWFLKITDYADELLQDINKLDNWPEAVKTMQINWIGKSKGLTVKFKVKDSNQE  241
            V +K + QW LKIT YA+ LL+D++ +D WPE++K MQ NWIGKS G  V FKVKD++++
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  242  IEVFTTRPDTLMGVNYLGIAPEHPLALKEAKSNSQLAAFIEECKKTSTMEADLA----TQ  297
            + VFTTRPDTL G  Y  +APEH+L   +A + S+ A  + + K+ +++ +DLA    ++
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALV--DAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  298  EKKGFKTSIKVIHPISAETIDVWVANFVLMGYGSGAVMSVPAHDQRDWEFAQKYNIPLKQ  357
            EK G  T+   I+P+++  + VW+A++VL +YG+GA+M+VPAHD+RDWEFA+++N+ +  
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  358  VIESNDNKLKIDLEKQAFTEKGILINSGEFDGLNFKNAYQAIKKYLTEQNKGYETTNFRI  417
            V+E+       ++E  AFTE G+ INS+ +DGL+  +A   +   L  +  G E   +R+
Sbjct  361  VLEGG------NVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRL  414

Query  418  HDWGISRQRYWGCPIPMIHCDDCGAVPEKEENLPVRLPTDVALTEAG---SPLKDIPEFI  474
            +DW +SRQRYWG PIP+IH +D  + +  E +LP+ LP    +  +G   SPL ++ + +
Sbjct  415  RDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWL  474

Query  475  NVACPECGKPAKRETDTFDTFFESSWYYARYTCPTANQMLDQEA--NYWLPVDKYIGGIE  532
            +V+  +  K ++RET+T      SSWYY RY  P   + L +E   + WLPVD Y+GG E
Sbjct  475  EVTREDGVK-GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAE  533

Query  533  HAIMHLLYARFFHKLMRDQGLVKSDEPFKNLLTQGMVL-------------------KDG  573
            HA++HLLYARF HK++ D G+V + EPF++L+ QGM+L                   +DG
Sbjct  534  HAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDG  593

Query  574  ---------------AKMSKSKGNIVDPQELIDKYGADTVRLFSMFAAPPEQSLEWSETG  618
                           AKMSKS  N+V+P++++++YGADT+R++ MF +P + S+ WSE G
Sbjct  594  SFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEG  653

Query  619  VEGANKFLRKVFNYAELNKVIFAKNITLESQKLTKEDKKARFEIHSNLKQAIFDFDKSQF  678
            +EG+ KFL +V+     + +   ++ +L+  K+ +E  KA   +  ++ Q  F+   +Q+
Sbjct  654  LEGSRKFLDRVYRLITTKEITEENSGALD--KVYNETVKA---VTEQVDQMKFNTAIAQL  708

Query  679  NTVVSACMKILNTLNNYDNLSESVKVEGFSILLRILAPFTPHLCHYLWQQLNL-GEDILH  737
               V+A  K  + +++Y +        GF   ++++APF+PHL + LWQ L   GE I  
Sbjct  709  MVFVNAANKEDKLFSDYAK--------GF---VQLIAPFAPHLGEELWQALTASGESISY  757

Query  738  TSFPTVDNNALEKDEFLLVVQINGKLKAKLELDASLSSNQVEEVVLADEHVKSFIDNKQV  797
             + P+ D++ L  ++  +VVQI+GK+KAKL +   LS ++++EV LA+E V++ I  K++
Sbjct  758  VPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDI  817

Query  798  VKVIYVPQKLINIVIK  813
            +KVI VP+KL+NIVIK
Sbjct  818  IKVIAVPNKLVNIVIK  833

987) leuS in NC_017453


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  551 bits (2081),  Expect = 5e-158, Method: Compositional matrix adjust.
 Identities = 355/856 (42%), Positives = 552/856 (65%), Gaps = 72/856 (8%)

Query  4    YNFSDIEKSTQEYWRKNDTFKTIEDNTKEKFYCLSMLPYPSGT-LHMGHVRNYTIGDVIA  62
            Y+ + IE   Q +W  N+TFKT  D +K KFY L M+PYPSG+ LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYQKMQGKNVLHPMGWDAFGLPAENAAIKHKKSPYEWTKSNIAYMRSQFDSLGFSFDWSR  122
            R+++ QG NVLHPMGWDAFGLPAE+ A+   + P E T  NIA  + Q+++LGFS+DW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EITTCDEDYYKWEQWFFIQLYKKGLAYRKNSVVNW-DPVDQTVLANEQVVDGRGWRSGAL  181
            E+ T D +YYKW QW+F +LY KGLAY  +  VNW + ++ ++  +E + DG + R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VEKKEIPQWFLKITDYADELLQDINKLDNWPEAVKTMQINWIGKSKGLTVKFKVKDSNQE  241
            V +K + QW LKIT YA+ LL+D++ +D WPE++K MQ NWIGKS G  V FKVKD++++
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  242  IEVFTTRPDTLMGVNYLGIAPEHPLALKEAKSNSQLAAFIEECKKTSTMEADLA----TQ  297
            + VFTTRPDTL G  Y  +APEH+L   +A + S+ A  + + K+ +++ +DLA    ++
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALV--DAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  298  EKKGFKTSIKVIHPISAETIDVWVANFVLMGYGSGAVMSVPAHDQRDWEFAQKYNIPLKQ  357
            EK G  T+   I+P+++  + VW+A++VL +YG+GA+M+VPAHD+RDWEFA+++N+ +  
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  358  VIESNDNKLKIDLEKQAFTEKGILINSGEFDGLNFKNAYQAIKKYLTEQNKGYETTNFRI  417
            V+E+       ++E  AFTE G+ INS+ +DGL+  +A   +   L  +  G E   +R+
Sbjct  361  VLEGG------NVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRL  414

Query  418  HDWGISRQRYWGCPIPMIHCDDCGAVPEKEENLPVRLPTDVALTEAG---SPLKDIPEFI  474
            +DW +SRQRYWG PIP+IH +D  + +  E +LP+ LP    +  +G   SPL ++ + +
Sbjct  415  RDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWL  474

Query  475  NVACPECGKPAKRETDTFDTFFESSWYYARYTCPTANQMLDQEA--NYWLPVDKYIGGIE  532
            +V+  +  K ++RET+T      SSWYY RY  P   + L +E   + WLPVD Y+GG E
Sbjct  475  EVTREDGVK-GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAE  533

Query  533  HAIMHLLYARFFHKLMRDQGLVKSDEPFKNLLTQGMVL-------------------KDG  573
            HA++HLLYARF HK++ D G+V + EPF++L+ QGM+L                   +DG
Sbjct  534  HAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDG  593

Query  574  ---------------AKMSKSKGNIVDPQELIDKYGADTVRLFSMFAAPPEQSLEWSETG  618
                           AKMSKS  N+V+P++++++YGADT+R++ MF +P + S+ WSE G
Sbjct  594  SFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEG  653

Query  619  VEGANKFLRKVFNYAELNKVIFAKNITLESQKLTKEDKKARFEIHSNLKQAIFDFDKSQF  678
            +EG+ KFL +V+     + +   ++ +L+  K+ +E  KA   +  ++ Q  F+   +Q+
Sbjct  654  LEGSRKFLDRVYRLITTKEITEENSGALD--KVYNETVKA---VTEQVDQMKFNTAIAQL  708

Query  679  NTVVSACMKILNTLNNYDNLSESVKVEGFSILLRILAPFTPHLCHYLWQQLNL-GEDILH  737
               V+A  K  + +++Y +        GF   ++++APF+PHL + LWQ L   GE I  
Sbjct  709  MVFVNAANKEDKLFSDYAK--------GF---VQLIAPFAPHLGEELWQALTASGESISY  757

Query  738  TSFPTVDNNALEKDEFLLVVQINGKLKAKLELDASLSSNQVEEVVLADEHVKSFIDNKQV  797
             + P+ D++ L  ++  +VVQI+GK+KAKL +   LS ++++EV LA+E V++ I  K++
Sbjct  758  VPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDI  817

Query  798  VKVIYVPQKLINIVIK  813
            +KVI VP+KL+NIVIK
Sbjct  818  IKVIAVPNKLVNIVIK  833

988) leuS in NC_006570


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  551 bits (2081),  Expect = 5e-158, Method: Compositional matrix adjust.
 Identities = 355/856 (42%), Positives = 552/856 (65%), Gaps = 72/856 (8%)

Query  4    YNFSDIEKSTQEYWRKNDTFKTIEDNTKEKFYCLSMLPYPSGT-LHMGHVRNYTIGDVIA  62
            Y+ + IE   Q +W  N+TFKT  D +K KFY L M+PYPSG+ LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYQKMQGKNVLHPMGWDAFGLPAENAAIKHKKSPYEWTKSNIAYMRSQFDSLGFSFDWSR  122
            R+++ QG NVLHPMGWDAFGLPAE+ A+   + P E T  NIA  + Q+++LGFS+DW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EITTCDEDYYKWEQWFFIQLYKKGLAYRKNSVVNW-DPVDQTVLANEQVVDGRGWRSGAL  181
            E+ T D +YYKW QW+F +LY KGLAY  +  VNW + ++ ++  +E + DG + R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VEKKEIPQWFLKITDYADELLQDINKLDNWPEAVKTMQINWIGKSKGLTVKFKVKDSNQE  241
            V +K + QW LKIT YA+ LL+D++ +D WPE++K MQ NWIGKS G  V FKVKD++++
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  242  IEVFTTRPDTLMGVNYLGIAPEHPLALKEAKSNSQLAAFIEECKKTSTMEADLA----TQ  297
            + VFTTRPDTL G  Y  +APEH+L   +A + S+ A  + + K+ +++ +DLA    ++
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALV--DAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  298  EKKGFKTSIKVIHPISAETIDVWVANFVLMGYGSGAVMSVPAHDQRDWEFAQKYNIPLKQ  357
            EK G  T+   I+P+++  + VW+A++VL +YG+GA+M+VPAHD+RDWEFA+++N+ +  
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  358  VIESNDNKLKIDLEKQAFTEKGILINSGEFDGLNFKNAYQAIKKYLTEQNKGYETTNFRI  417
            V+E+       ++E  AFTE G+ INS+ +DGL+  +A   +   L  +  G E   +R+
Sbjct  361  VLEGG------NVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRL  414

Query  418  HDWGISRQRYWGCPIPMIHCDDCGAVPEKEENLPVRLPTDVALTEAG---SPLKDIPEFI  474
            +DW +SRQRYWG PIP+IH +D  + +  E +LP+ LP    +  +G   SPL ++ + +
Sbjct  415  RDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWL  474

Query  475  NVACPECGKPAKRETDTFDTFFESSWYYARYTCPTANQMLDQEA--NYWLPVDKYIGGIE  532
            +V+  +  K ++RET+T      SSWYY RY  P   + L +E   + WLPVD Y+GG E
Sbjct  475  EVTREDGVK-GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAE  533

Query  533  HAIMHLLYARFFHKLMRDQGLVKSDEPFKNLLTQGMVL-------------------KDG  573
            HA++HLLYARF HK++ D G+V + EPF++L+ QGM+L                   +DG
Sbjct  534  HAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDG  593

Query  574  ---------------AKMSKSKGNIVDPQELIDKYGADTVRLFSMFAAPPEQSLEWSETG  618
                           AKMSKS  N+V+P++++++YGADT+R++ MF +P + S+ WSE G
Sbjct  594  SFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEG  653

Query  619  VEGANKFLRKVFNYAELNKVIFAKNITLESQKLTKEDKKARFEIHSNLKQAIFDFDKSQF  678
            +EG+ KFL +V+     + +   ++ +L+  K+ +E  KA   +  ++ Q  F+   +Q+
Sbjct  654  LEGSRKFLDRVYRLITTKEITEENSGALD--KVYNETVKA---VTEQVDQMKFNTAIAQL  708

Query  679  NTVVSACMKILNTLNNYDNLSESVKVEGFSILLRILAPFTPHLCHYLWQQLNL-GEDILH  737
               V+A  K  + +++Y +        GF   ++++APF+PHL + LWQ L   GE I  
Sbjct  709  MVFVNAANKEDKLFSDYAK--------GF---VQLIAPFAPHLGEELWQALTASGESISY  757

Query  738  TSFPTVDNNALEKDEFLLVVQINGKLKAKLELDASLSSNQVEEVVLADEHVKSFIDNKQV  797
             + P+ D++ L  ++  +VVQI+GK+KAKL +   LS ++++EV LA+E V++ I  K++
Sbjct  758  VPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDI  817

Query  798  VKVIYVPQKLINIVIK  813
            +KVI VP+KL+NIVIK
Sbjct  818  IKVIAVPNKLVNIVIK  833

989) leuS in NC_016937


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  551 bits (2081),  Expect = 5e-158, Method: Compositional matrix adjust.
 Identities = 355/856 (42%), Positives = 552/856 (65%), Gaps = 72/856 (8%)

Query  4    YNFSDIEKSTQEYWRKNDTFKTIEDNTKEKFYCLSMLPYPSGT-LHMGHVRNYTIGDVIA  62
            Y+ + IE   Q +W  N+TFKT  D +K KFY L M+PYPSG+ LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYQKMQGKNVLHPMGWDAFGLPAENAAIKHKKSPYEWTKSNIAYMRSQFDSLGFSFDWSR  122
            R+++ QG NVLHPMGWDAFGLPAE+ A+   + P E T  NIA  + Q+++LGFS+DW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EITTCDEDYYKWEQWFFIQLYKKGLAYRKNSVVNW-DPVDQTVLANEQVVDGRGWRSGAL  181
            E+ T D +YYKW QW+F +LY KGLAY  +  VNW + ++ ++  +E + DG + R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VEKKEIPQWFLKITDYADELLQDINKLDNWPEAVKTMQINWIGKSKGLTVKFKVKDSNQE  241
            V +K + QW LKIT YA+ LL+D++ +D WPE++K MQ NWIGKS G  V FKVKD++++
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  242  IEVFTTRPDTLMGVNYLGIAPEHPLALKEAKSNSQLAAFIEECKKTSTMEADLA----TQ  297
            + VFTTRPDTL G  Y  +APEH+L   +A + S+ A  + + K+ +++ +DLA    ++
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALV--DAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  298  EKKGFKTSIKVIHPISAETIDVWVANFVLMGYGSGAVMSVPAHDQRDWEFAQKYNIPLKQ  357
            EK G  T+   I+P+++  + VW+A++VL +YG+GA+M+VPAHD+RDWEFA+++N+ +  
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  358  VIESNDNKLKIDLEKQAFTEKGILINSGEFDGLNFKNAYQAIKKYLTEQNKGYETTNFRI  417
            V+E+       ++E  AFTE G+ INS+ +DGL+  +A   +   L  +  G E   +R+
Sbjct  361  VLEGG------NVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRL  414

Query  418  HDWGISRQRYWGCPIPMIHCDDCGAVPEKEENLPVRLPTDVALTEAG---SPLKDIPEFI  474
            +DW +SRQRYWG PIP+IH +D  + +  E +LP+ LP    +  +G   SPL ++ + +
Sbjct  415  RDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWL  474

Query  475  NVACPECGKPAKRETDTFDTFFESSWYYARYTCPTANQMLDQEA--NYWLPVDKYIGGIE  532
            +V+  +  K ++RET+T      SSWYY RY  P   + L +E   + WLPVD Y+GG E
Sbjct  475  EVTREDGVK-GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAE  533

Query  533  HAIMHLLYARFFHKLMRDQGLVKSDEPFKNLLTQGMVL-------------------KDG  573
            HA++HLLYARF HK++ D G+V + EPF++L+ QGM+L                   +DG
Sbjct  534  HAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDG  593

Query  574  ---------------AKMSKSKGNIVDPQELIDKYGADTVRLFSMFAAPPEQSLEWSETG  618
                           AKMSKS  N+V+P++++++YGADT+R++ MF +P + S+ WSE G
Sbjct  594  SFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEG  653

Query  619  VEGANKFLRKVFNYAELNKVIFAKNITLESQKLTKEDKKARFEIHSNLKQAIFDFDKSQF  678
            +EG+ KFL +V+     + +   ++ +L+  K+ +E  KA   +  ++ Q  F+   +Q+
Sbjct  654  LEGSRKFLDRVYRLITTKEITEENSGALD--KVYNETVKA---VTEQVDQMKFNTAIAQL  708

Query  679  NTVVSACMKILNTLNNYDNLSESVKVEGFSILLRILAPFTPHLCHYLWQQLNL-GEDILH  737
               V+A  K  + +++Y +        GF   ++++APF+PHL + LWQ L   GE I  
Sbjct  709  MVFVNAANKEDKLFSDYAK--------GF---VQLIAPFAPHLGEELWQALTASGESISY  757

Query  738  TSFPTVDNNALEKDEFLLVVQINGKLKAKLELDASLSSNQVEEVVLADEHVKSFIDNKQV  797
             + P+ D++ L  ++  +VVQI+GK+KAKL +   LS ++++EV LA+E V++ I  K++
Sbjct  758  VPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDI  817

Query  798  VKVIYVPQKLINIVIK  813
            +KVI VP+KL+NIVIK
Sbjct  818  IKVIAVPNKLVNIVIK  833

990) leuS in NC_016933


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  551 bits (2081),  Expect = 5e-158, Method: Compositional matrix adjust.
 Identities = 355/856 (42%), Positives = 552/856 (65%), Gaps = 72/856 (8%)

Query  4    YNFSDIEKSTQEYWRKNDTFKTIEDNTKEKFYCLSMLPYPSGT-LHMGHVRNYTIGDVIA  62
            Y+ + IE   Q +W  N+TFKT  D +K KFY L M+PYPSG+ LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYQKMQGKNVLHPMGWDAFGLPAENAAIKHKKSPYEWTKSNIAYMRSQFDSLGFSFDWSR  122
            R+++ QG NVLHPMGWDAFGLPAE+ A+   + P E T  NIA  + Q+++LGFS+DW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EITTCDEDYYKWEQWFFIQLYKKGLAYRKNSVVNW-DPVDQTVLANEQVVDGRGWRSGAL  181
            E+ T D +YYKW QW+F +LY KGLAY  +  VNW + ++ ++  +E + DG + R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VEKKEIPQWFLKITDYADELLQDINKLDNWPEAVKTMQINWIGKSKGLTVKFKVKDSNQE  241
            V +K + QW LKIT YA+ LL+D++ +D WPE++K MQ NWIGKS G  V FKVKD++++
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  242  IEVFTTRPDTLMGVNYLGIAPEHPLALKEAKSNSQLAAFIEECKKTSTMEADLA----TQ  297
            + VFTTRPDTL G  Y  +APEH+L   +A + S+ A  + + K+ +++ +DLA    ++
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALV--DAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  298  EKKGFKTSIKVIHPISAETIDVWVANFVLMGYGSGAVMSVPAHDQRDWEFAQKYNIPLKQ  357
            EK G  T+   I+P+++  + VW+A++VL +YG+GA+M+VPAHD+RDWEFA+++N+ +  
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  358  VIESNDNKLKIDLEKQAFTEKGILINSGEFDGLNFKNAYQAIKKYLTEQNKGYETTNFRI  417
            V+E+       ++E  AFTE G+ INS+ +DGL+  +A   +   L  +  G E   +R+
Sbjct  361  VLEGG------NVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRL  414

Query  418  HDWGISRQRYWGCPIPMIHCDDCGAVPEKEENLPVRLPTDVALTEAG---SPLKDIPEFI  474
            +DW +SRQRYWG PIP+IH +D  + +  E +LP+ LP    +  +G   SPL ++ + +
Sbjct  415  RDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWL  474

Query  475  NVACPECGKPAKRETDTFDTFFESSWYYARYTCPTANQMLDQEA--NYWLPVDKYIGGIE  532
            +V+  +  K ++RET+T      SSWYY RY  P   + L +E   + WLPVD Y+GG E
Sbjct  475  EVTREDGVK-GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAE  533

Query  533  HAIMHLLYARFFHKLMRDQGLVKSDEPFKNLLTQGMVL-------------------KDG  573
            HA++HLLYARF HK++ D G+V + EPF++L+ QGM+L                   +DG
Sbjct  534  HAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDG  593

Query  574  ---------------AKMSKSKGNIVDPQELIDKYGADTVRLFSMFAAPPEQSLEWSETG  618
                           AKMSKS  N+V+P++++++YGADT+R++ MF +P + S+ WSE G
Sbjct  594  SFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEG  653

Query  619  VEGANKFLRKVFNYAELNKVIFAKNITLESQKLTKEDKKARFEIHSNLKQAIFDFDKSQF  678
            +EG+ KFL +V+     + +   ++ +L+  K+ +E  KA   +  ++ Q  F+   +Q+
Sbjct  654  LEGSRKFLDRVYRLITTKEITEENSGALD--KVYNETVKA---VTEQVDQMKFNTAIAQL  708

Query  679  NTVVSACMKILNTLNNYDNLSESVKVEGFSILLRILAPFTPHLCHYLWQQLNL-GEDILH  737
               V+A  K  + +++Y +        GF   ++++APF+PHL + LWQ L   GE I  
Sbjct  709  MVFVNAANKEDKLFSDYAK--------GF---VQLIAPFAPHLGEELWQALTASGESISY  757

Query  738  TSFPTVDNNALEKDEFLLVVQINGKLKAKLELDASLSSNQVEEVVLADEHVKSFIDNKQV  797
             + P+ D++ L  ++  +VVQI+GK+KAKL +   LS ++++EV LA+E V++ I  K++
Sbjct  758  VPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDI  817

Query  798  VKVIYVPQKLINIVIK  813
            +KVI VP+KL+NIVIK
Sbjct  818  IKVIAVPNKLVNIVIK  833

991) leuS in NC_009348


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  551 bits (2081),  Expect = 6e-158, Method: Compositional matrix adjust.
 Identities = 358/865 (42%), Positives = 562/865 (65%), Gaps = 46/865 (5%)

Query  5    YVPQSIEPAVQKHWDAKKTFKAVEKVDKEKFYCLSMFPYPSGR-LHMGHVRNYTIGDVIS  63
            Y   +IEP  Q  W  + TFK+     K KFY L MFPYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRLNGKNVLQPIGWDAFGLPAENAAVKNNTAPAPWTYENIEYMKNQLKMLGLGYDWDR  123
            R++R +G NVL+P+GWDAFGLPAE+ A+     PA  T ENI   K Q++ LG++YDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCKPDYYRWEQWFFTKLYEKGLVYKKTSSVNWCPNDMTVLANEQVV-DNCCWRCDTP  182
            E+ T  P+YY+W QW+FTKLYEKGL Y    +VNW  +  T +ANE+V+ D    R + P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VEQKEIPQWFIKITDYAEELLNDIDNLEGWPEMVKTMQRNWIGRSEGVNISFAIEGQAEQ  242
            V +K + QW +KIT YAE LL+D+++++ WPE +K MQRNWIG+S G N++F + +   +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LEVYTTRPDTFMGVTYVGIaaghplalqaaaTNPGLAAFIEECKNTKVAEAELA----TM  298
            + V+TTRPDT+ G TY  +A+ H+L    ++++ + A  + + K      ++LA    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEA--VADYKRQASLKSDLARTDLAK  300

Query  299  EKKGMATGLYAIHPLDGRKVPVWVANFVLMNYGTGAVMAVPGHDQRDHEFATKYGLDIKA  358
            EK G+ TG YAI+P++G+ +PVW+A++VL +YGTGA+MAVP+HD+RD EFA ++ LDI +
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VIKPADGEVDVSDAAYTEKGVLFASGEFDGLDFQGAFDAIANKLEALGHGKRTVNFRLRD  418
            V+  +    +V +AA+TE G+ + S+ +DGLD  +A+  + + LEA G G+  V +RLRD
Sbjct  361  VLEGG----NVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  419  WGVSRQRYWGAPIPMLTLADGTVVPTPEDQLPVLLP--EDVVMDGI-QSPIKADAEWAKT  475
            W  SRQRYWG PIP++   DGT  + PE +LP++LP   D+   G  +SP+   ++W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  476  TY-NGQEAFRETDTFDTFMESSWYYARYCSPDYDKGMLDPAAANHWLPVDQYIGGIEHAC  534
            T  +G  + RET+T      SSWYY RY  P+    + D    ++WLPVD Y+GG EHA 
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  535  MHLLYARFFHKLLRDAGLVNSDEPFKRLLCQGMVLADAFYYKDEKGGNVWVSPTDVKVER  594
            +HLLYARF HK+L D G+V + EPF++L+ QGM+L+ +  Y+D +G+ V    +  KVE+
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS--YRDSRGALV----ATDKVEK  590

Query  595  DEKGRITKAIDNDGREVIHSGMTKMSKSKNNGIDPQLMVERYGADTVRLFMMFASPAEMT  654
                R    ++ +  E ++ + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P + +
Sbjct  591  ----RDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  655  LEWSDSGVEGAQRFLRRLWRLTFEHVSAGAVPALDVAALTSEQKAVRRELHKTIAKVSDD  714
            + WS+ G+EG+++FL R+ RL    +++  +   + +AL        +  + T+  V+++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRL----ITTKEITEENSGALD-------KVYNETVKAVTEQ  695

Query  715  VGRRQTFNTAIAAIMELMNNLAKLGSDEQDRALMQEALETVVVMLSPITPHIGFELWKML  774
            V++ + FNTAIA +M ++N      + +++  L  +     V +++P++PH+G ELW+ L
Sbjct  696  VDQMK-FNTAIAQLMVFVN------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQAL  748

Query  775  -GKGDDVDHATWPVADEAAMVETEKLVVVQINGKMRGKLTVPAEISQADVEKLAMADASV  833
             + G+ +    WP  DE+ +VE +  +VVQI+GK+++KL V+ ++S+ +++ +A+A+  V
Sbjct  749  TASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKV  808

Query  834  QKFTDGLTVRKVIYVPGKLLNIVAN  858
            Q    G  + KVI VP KL+NIV +
Sbjct  809  QAEIAGKDIIKVIAVPNKLVNIVIK  833

992) leuS in NC_017168


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  551 bits (2081),  Expect = 6e-158, Method: Compositional matrix adjust.
 Identities = 357/866 (42%), Positives = 552/866 (64%), Gaps = 48/866 (5%)

Query  5    YRPEDIETQVQLHWQEKQTFKVTEDASKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIS  63
            Y    IE + Q  W +++TFK   DASK K+Y L M+PYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIEYMKNQLKLLGFGYDWDR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NI   K Q++ LGF+YDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EIATCKPDYYRWEQWFFTKLYEKGMVYKKTSAVNWCPHDLTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W QW+FTKLYEKG+ Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITDYAEQLLNDLDTLESWPEQVKTMQRNWIGRSEGVDIVFDVVDSEEK  242
            V RK + QW +KIT YAE+LL+DL+ ++ WPE +K MQRNWIG+S G ++ F V D++  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LSVYTTRPDTFMGVTYVAVAAGHPLSLQAAATNPALADFVAECRNTKVAEAEMA----TM  298
            ++V+TTRPDT+ G TY  +A+ H+L    A T +  A+ VA+ +      +++A    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALV--DAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  299  EKKGMATGLYAIHPLTGEKLPIWAANFVLMDYGTGAVMAVPGHDARDWEFATKYNLPIKP  358
            EK G+ TG YAI+P+ G  +P+W A++VL  YGTGA+MAVP+HD RDWEFA ++NL I P
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VILAADGSEPDLSQEAMTEKGTLFNSGEFDGLNHEDGFNAIADKLVALGVGQRKVNYRLR  418
            V+ +++  E+ ++++++  ++ +     +DGL+   ++  + + L A GVG+ +V YRLR
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDF-----LDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  419  DWGVSRQRYWGAPIPMVTLEDGTVVPTPEDQLPVILP--EDVVMDGIS-SPIKADPEWAK  475
            DW  SRQRYWG PIP++  EDGT  + PE +LP++LP   D+   G + SP+    +W  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  476  TT-VNGIPGLRETDTFDTFMESSWYYARYTCPQYDDGMLDPAAANYWLPVDQYVGGIEHA  534
             T  +G+ G RET+T      SSWYY RY  P+  + + D    + WLPVD YVGG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  535  IMHLMYFRFFHKLLRDAGLVDSDEPAKRLLCQGMVLADAFYYTGNNGERIWVSPVDAIVE  594
            ++HL+Y RF HK+L D G+V + EP ++L+ QGM+L+ +  Y ++ G    + + D +  
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS--YRDSRGA---LVATDKVEK  590

Query  595  RDDKGRIVKAVDAEGHELVYAGMSKMSKSKNNGIDPQVMVEKYGADTVRLFMMFASPAEM  654
            RD  G +     +E  E    + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P + 
Sbjct  591  RD--GSFFHVETGEELE---QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  655  TLEWQESGVEGANRFLKRVWRLAFDHTAKGAVKPLDIASLTEEQKSLRRDLHKTIAKVTD  714
            ++ W E G+EG+ +FL RV RL         +   +I+   E+  +L +  + T+  VT+
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRL---------ITTKEITE--ENSGALDKVYNETVKAVTE  694

Query  715  DVGRRQTFNTAIAAVMELMNKLGRAPQETEQDRALMQEALLAVVRMLYPFTPHVCFSLWQ  774
            +V++ + FNTAIA +M ++N        ++++  L  +   + V+++ PF+PH+   LWQ
Sbjct  695  QVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  775  ALGGEGD-IDTAPWPIADEQAMVEDSKLVVVQVNGKVRGRITVPADATEQQVRERAGQEH  833
            AL + G+ I   PWP  DE  +VE+   +VVQ++GKV++++ V+ D + ++++E A  ++
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  834  LVAKYLDGVTVRKVIYVPGKLLNLVV  859
             V   + G  + KVI VP KL+N+V+
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVI  832

993) leuS in NC_008150


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  551 bits (2081),  Expect = 6e-158, Method: Compositional matrix adjust.
 Identities = 357/866 (42%), Positives = 552/866 (64%), Gaps = 48/866 (5%)

Query  5    YRPEDIETQVQLHWQEKQTFKVTEDASKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIS  63
            Y    IE + Q  W +++TFK   DASK K+Y L M+PYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIEYMKNQLKLLGFGYDWDR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NI   K Q++ LGF+YDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EIATCKPDYYRWEQWFFTKLYEKGMVYKKTSAVNWCPHDLTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W QW+FTKLYEKG+ Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITDYAEQLLNDLDTLESWPEQVKTMQRNWIGRSEGVDIVFDVVDSEEK  242
            V RK + QW +KIT YAE+LL+DL+ ++ WPE +K MQRNWIG+S G ++ F V D++  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LSVYTTRPDTFMGVTYVAVAAGHPLSLQAAATNPALADFVAECRNTKVAEAEMA----TM  298
            ++V+TTRPDT+ G TY  +A+ H+L    A T +  A+ VA+ +      +++A    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALV--DAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  299  EKKGMATGLYAIHPLTGEKLPIWAANFVLMDYGTGAVMAVPGHDARDWEFATKYNLPIKP  358
            EK G+ TG YAI+P+ G  +P+W A++VL  YGTGA+MAVP+HD RDWEFA ++NL I P
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VILAADGSEPDLSQEAMTEKGTLFNSGEFDGLNHEDGFNAIADKLVALGVGQRKVNYRLR  418
            V+ +++  E+ ++++++  ++ +     +DGL+   ++  + + L A GVG+ +V YRLR
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDF-----LDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  419  DWGVSRQRYWGAPIPMVTLEDGTVVPTPEDQLPVILP--EDVVMDGIS-SPIKADPEWAK  475
            DW  SRQRYWG PIP++  EDGT  + PE +LP++LP   D+   G + SP+    +W  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  476  TT-VNGIPGLRETDTFDTFMESSWYYARYTCPQYDDGMLDPAAANYWLPVDQYVGGIEHA  534
             T  +G+ G RET+T      SSWYY RY  P+  + + D    + WLPVD YVGG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  535  IMHLMYFRFFHKLLRDAGLVDSDEPAKRLLCQGMVLADAFYYTGNNGERIWVSPVDAIVE  594
            ++HL+Y RF HK+L D G+V + EP ++L+ QGM+L+ +  Y ++ G    + + D +  
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS--YRDSRGA---LVATDKVEK  590

Query  595  RDDKGRIVKAVDAEGHELVYAGMSKMSKSKNNGIDPQVMVEKYGADTVRLFMMFASPAEM  654
            RD  G +     +E  E    + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P + 
Sbjct  591  RD--GSFFHVETGEELE---QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  655  TLEWQESGVEGANRFLKRVWRLAFDHTAKGAVKPLDIASLTEEQKSLRRDLHKTIAKVTD  714
            ++ W E G+EG+ +FL RV RL         +   +I+   E+  +L +  + T+  VT+
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRL---------ITTKEITE--ENSGALDKVYNETVKAVTE  694

Query  715  DVGRRQTFNTAIAAVMELMNKLGRAPQETEQDRALMQEALLAVVRMLYPFTPHVCFSLWQ  774
            +V++ + FNTAIA +M ++N        ++++  L  +   + V+++ PF+PH+   LWQ
Sbjct  695  QVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  775  ALGGEGD-IDTAPWPIADEQAMVEDSKLVVVQVNGKVRGRITVPADATEQQVRERAGQEH  833
            AL + G+ I   PWP  DE  +VE+   +VVQ++GKV++++ V+ D + ++++E A  ++
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  834  LVAKYLDGVTVRKVIYVPGKLLNLVV  859
             V   + G  + KVI VP KL+N+V+
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVI  832

994) leuS in NC_017265


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  551 bits (2081),  Expect = 6e-158, Method: Compositional matrix adjust.
 Identities = 357/866 (42%), Positives = 552/866 (64%), Gaps = 48/866 (5%)

Query  5    YRPEDIETQVQLHWQEKQTFKVTEDASKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIS  63
            Y    IE + Q  W +++TFK   DASK K+Y L M+PYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIEYMKNQLKLLGFGYDWDR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NI   K Q++ LGF+YDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EIATCKPDYYRWEQWFFTKLYEKGMVYKKTSAVNWCPHDLTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W QW+FTKLYEKG+ Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITDYAEQLLNDLDTLESWPEQVKTMQRNWIGRSEGVDIVFDVVDSEEK  242
            V RK + QW +KIT YAE+LL+DL+ ++ WPE +K MQRNWIG+S G ++ F V D++  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LSVYTTRPDTFMGVTYVAVAAGHPLSLQAAATNPALADFVAECRNTKVAEAEMA----TM  298
            ++V+TTRPDT+ G TY  +A+ H+L    A T +  A+ VA+ +      +++A    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALV--DAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  299  EKKGMATGLYAIHPLTGEKLPIWAANFVLMDYGTGAVMAVPGHDARDWEFATKYNLPIKP  358
            EK G+ TG YAI+P+ G  +P+W A++VL  YGTGA+MAVP+HD RDWEFA ++NL I P
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VILAADGSEPDLSQEAMTEKGTLFNSGEFDGLNHEDGFNAIADKLVALGVGQRKVNYRLR  418
            V+ +++  E+ ++++++  ++ +     +DGL+   ++  + + L A GVG+ +V YRLR
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDF-----LDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  419  DWGVSRQRYWGAPIPMVTLEDGTVVPTPEDQLPVILP--EDVVMDGIS-SPIKADPEWAK  475
            DW  SRQRYWG PIP++  EDGT  + PE +LP++LP   D+   G + SP+    +W  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  476  TT-VNGIPGLRETDTFDTFMESSWYYARYTCPQYDDGMLDPAAANYWLPVDQYVGGIEHA  534
             T  +G+ G RET+T      SSWYY RY  P+  + + D    + WLPVD YVGG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  535  IMHLMYFRFFHKLLRDAGLVDSDEPAKRLLCQGMVLADAFYYTGNNGERIWVSPVDAIVE  594
            ++HL+Y RF HK+L D G+V + EP ++L+ QGM+L+ +  Y ++ G    + + D +  
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS--YRDSRGA---LVATDKVEK  590

Query  595  RDDKGRIVKAVDAEGHELVYAGMSKMSKSKNNGIDPQVMVEKYGADTVRLFMMFASPAEM  654
            RD  G +     +E  E    + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P + 
Sbjct  591  RD--GSFFHVETGEELE---QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  655  TLEWQESGVEGANRFLKRVWRLAFDHTAKGAVKPLDIASLTEEQKSLRRDLHKTIAKVTD  714
            ++ W E G+EG+ +FL RV RL         +   +I+   E+  +L +  + T+  VT+
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRL---------ITTKEITE--ENSGALDKVYNETVKAVTE  694

Query  715  DVGRRQTFNTAIAAVMELMNKLGRAPQETEQDRALMQEALLAVVRMLYPFTPHVCFSLWQ  774
            +V++ + FNTAIA +M ++N        ++++  L  +   + V+++ PF+PH+   LWQ
Sbjct  695  QVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  775  ALGGEGD-IDTAPWPIADEQAMVEDSKLVVVQVNGKVRGRITVPADATEQQVRERAGQEH  833
            AL + G+ I   PWP  DE  +VE+   +VVQ++GKV++++ V+ D + ++++E A  ++
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  834  LVAKYLDGVTVRKVIYVPGKLLNLVV  859
             V   + G  + KVI VP KL+N+V+
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVI  832

995) leuS in NC_005810


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  551 bits (2081),  Expect = 6e-158, Method: Compositional matrix adjust.
 Identities = 357/866 (42%), Positives = 552/866 (64%), Gaps = 48/866 (5%)

Query  5    YRPEDIETQVQLHWQEKQTFKVTEDASKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIS  63
            Y    IE + Q  W +++TFK   DASK K+Y L M+PYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIEYMKNQLKLLGFGYDWDR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NI   K Q++ LGF+YDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EIATCKPDYYRWEQWFFTKLYEKGMVYKKTSAVNWCPHDLTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W QW+FTKLYEKG+ Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITDYAEQLLNDLDTLESWPEQVKTMQRNWIGRSEGVDIVFDVVDSEEK  242
            V RK + QW +KIT YAE+LL+DL+ ++ WPE +K MQRNWIG+S G ++ F V D++  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LSVYTTRPDTFMGVTYVAVAAGHPLSLQAAATNPALADFVAECRNTKVAEAEMA----TM  298
            ++V+TTRPDT+ G TY  +A+ H+L    A T +  A+ VA+ +      +++A    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALV--DAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  299  EKKGMATGLYAIHPLTGEKLPIWAANFVLMDYGTGAVMAVPGHDARDWEFATKYNLPIKP  358
            EK G+ TG YAI+P+ G  +P+W A++VL  YGTGA+MAVP+HD RDWEFA ++NL I P
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VILAADGSEPDLSQEAMTEKGTLFNSGEFDGLNHEDGFNAIADKLVALGVGQRKVNYRLR  418
            V+ +++  E+ ++++++  ++ +     +DGL+   ++  + + L A GVG+ +V YRLR
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDF-----LDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  419  DWGVSRQRYWGAPIPMVTLEDGTVVPTPEDQLPVILP--EDVVMDGIS-SPIKADPEWAK  475
            DW  SRQRYWG PIP++  EDGT  + PE +LP++LP   D+   G + SP+    +W  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  476  TT-VNGIPGLRETDTFDTFMESSWYYARYTCPQYDDGMLDPAAANYWLPVDQYVGGIEHA  534
             T  +G+ G RET+T      SSWYY RY  P+  + + D    + WLPVD YVGG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  535  IMHLMYFRFFHKLLRDAGLVDSDEPAKRLLCQGMVLADAFYYTGNNGERIWVSPVDAIVE  594
            ++HL+Y RF HK+L D G+V + EP ++L+ QGM+L+ +  Y ++ G    + + D +  
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS--YRDSRGA---LVATDKVEK  590

Query  595  RDDKGRIVKAVDAEGHELVYAGMSKMSKSKNNGIDPQVMVEKYGADTVRLFMMFASPAEM  654
            RD  G +     +E  E    + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P + 
Sbjct  591  RD--GSFFHVETGEELE---QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  655  TLEWQESGVEGANRFLKRVWRLAFDHTAKGAVKPLDIASLTEEQKSLRRDLHKTIAKVTD  714
            ++ W E G+EG+ +FL RV RL         +   +I+   E+  +L +  + T+  VT+
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRL---------ITTKEITE--ENSGALDKVYNETVKAVTE  694

Query  715  DVGRRQTFNTAIAAVMELMNKLGRAPQETEQDRALMQEALLAVVRMLYPFTPHVCFSLWQ  774
            +V++ + FNTAIA +M ++N        ++++  L  +   + V+++ PF+PH+   LWQ
Sbjct  695  QVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  775  ALGGEGD-IDTAPWPIADEQAMVEDSKLVVVQVNGKVRGRITVPADATEQQVRERAGQEH  833
            AL + G+ I   PWP  DE  +VE+   +VVQ++GKV++++ V+ D + ++++E A  ++
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  834  LVAKYLDGVTVRKVIYVPGKLLNLVV  859
             V   + G  + KVI VP KL+N+V+
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVI  832

996) leuS in NC_003143


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  551 bits (2081),  Expect = 6e-158, Method: Compositional matrix adjust.
 Identities = 357/866 (42%), Positives = 552/866 (64%), Gaps = 48/866 (5%)

Query  5    YRPEDIETQVQLHWQEKQTFKVTEDASKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIS  63
            Y    IE + Q  W +++TFK   DASK K+Y L M+PYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIEYMKNQLKLLGFGYDWDR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NI   K Q++ LGF+YDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EIATCKPDYYRWEQWFFTKLYEKGMVYKKTSAVNWCPHDLTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W QW+FTKLYEKG+ Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITDYAEQLLNDLDTLESWPEQVKTMQRNWIGRSEGVDIVFDVVDSEEK  242
            V RK + QW +KIT YAE+LL+DL+ ++ WPE +K MQRNWIG+S G ++ F V D++  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LSVYTTRPDTFMGVTYVAVAAGHPLSLQAAATNPALADFVAECRNTKVAEAEMA----TM  298
            ++V+TTRPDT+ G TY  +A+ H+L    A T +  A+ VA+ +      +++A    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALV--DAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  299  EKKGMATGLYAIHPLTGEKLPIWAANFVLMDYGTGAVMAVPGHDARDWEFATKYNLPIKP  358
            EK G+ TG YAI+P+ G  +P+W A++VL  YGTGA+MAVP+HD RDWEFA ++NL I P
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VILAADGSEPDLSQEAMTEKGTLFNSGEFDGLNHEDGFNAIADKLVALGVGQRKVNYRLR  418
            V+ +++  E+ ++++++  ++ +     +DGL+   ++  + + L A GVG+ +V YRLR
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDF-----LDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  419  DWGVSRQRYWGAPIPMVTLEDGTVVPTPEDQLPVILP--EDVVMDGIS-SPIKADPEWAK  475
            DW  SRQRYWG PIP++  EDGT  + PE +LP++LP   D+   G + SP+    +W  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  476  TT-VNGIPGLRETDTFDTFMESSWYYARYTCPQYDDGMLDPAAANYWLPVDQYVGGIEHA  534
             T  +G+ G RET+T      SSWYY RY  P+  + + D    + WLPVD YVGG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  535  IMHLMYFRFFHKLLRDAGLVDSDEPAKRLLCQGMVLADAFYYTGNNGERIWVSPVDAIVE  594
            ++HL+Y RF HK+L D G+V + EP ++L+ QGM+L+ +  Y ++ G    + + D +  
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS--YRDSRGA---LVATDKVEK  590

Query  595  RDDKGRIVKAVDAEGHELVYAGMSKMSKSKNNGIDPQVMVEKYGADTVRLFMMFASPAEM  654
            RD  G +     +E  E    + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P + 
Sbjct  591  RD--GSFFHVETGEELE---QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  655  TLEWQESGVEGANRFLKRVWRLAFDHTAKGAVKPLDIASLTEEQKSLRRDLHKTIAKVTD  714
            ++ W E G+EG+ +FL RV RL         +   +I+   E+  +L +  + T+  VT+
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRL---------ITTKEITE--ENSGALDKVYNETVKAVTE  694

Query  715  DVGRRQTFNTAIAAVMELMNKLGRAPQETEQDRALMQEALLAVVRMLYPFTPHVCFSLWQ  774
            +V++ + FNTAIA +M ++N        ++++  L  +   + V+++ PF+PH+   LWQ
Sbjct  695  QVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  775  ALGGEGD-IDTAPWPIADEQAMVEDSKLVVVQVNGKVRGRITVPADATEQQVRERAGQEH  833
            AL + G+ I   PWP  DE  +VE+   +VVQ++GKV++++ V+ D + ++++E A  ++
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  834  LVAKYLDGVTVRKVIYVPGKLLNLVV  859
             V   + G  + KVI VP KL+N+V+
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVI  832

997) leuS in NC_017154


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  551 bits (2081),  Expect = 6e-158, Method: Compositional matrix adjust.
 Identities = 357/866 (42%), Positives = 552/866 (64%), Gaps = 48/866 (5%)

Query  5    YRPEDIETQVQLHWQEKQTFKVTEDASKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIS  63
            Y    IE + Q  W +++TFK   DASK K+Y L M+PYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIEYMKNQLKLLGFGYDWDR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NI   K Q++ LGF+YDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EIATCKPDYYRWEQWFFTKLYEKGMVYKKTSAVNWCPHDLTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W QW+FTKLYEKG+ Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITDYAEQLLNDLDTLESWPEQVKTMQRNWIGRSEGVDIVFDVVDSEEK  242
            V RK + QW +KIT YAE+LL+DL+ ++ WPE +K MQRNWIG+S G ++ F V D++  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LSVYTTRPDTFMGVTYVAVAAGHPLSLQAAATNPALADFVAECRNTKVAEAEMA----TM  298
            ++V+TTRPDT+ G TY  +A+ H+L    A T +  A+ VA+ +      +++A    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALV--DAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  299  EKKGMATGLYAIHPLTGEKLPIWAANFVLMDYGTGAVMAVPGHDARDWEFATKYNLPIKP  358
            EK G+ TG YAI+P+ G  +P+W A++VL  YGTGA+MAVP+HD RDWEFA ++NL I P
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VILAADGSEPDLSQEAMTEKGTLFNSGEFDGLNHEDGFNAIADKLVALGVGQRKVNYRLR  418
            V+ +++  E+ ++++++  ++ +     +DGL+   ++  + + L A GVG+ +V YRLR
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDF-----LDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  419  DWGVSRQRYWGAPIPMVTLEDGTVVPTPEDQLPVILP--EDVVMDGIS-SPIKADPEWAK  475
            DW  SRQRYWG PIP++  EDGT  + PE +LP++LP   D+   G + SP+    +W  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  476  TT-VNGIPGLRETDTFDTFMESSWYYARYTCPQYDDGMLDPAAANYWLPVDQYVGGIEHA  534
             T  +G+ G RET+T      SSWYY RY  P+  + + D    + WLPVD YVGG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  535  IMHLMYFRFFHKLLRDAGLVDSDEPAKRLLCQGMVLADAFYYTGNNGERIWVSPVDAIVE  594
            ++HL+Y RF HK+L D G+V + EP ++L+ QGM+L+ +  Y ++ G    + + D +  
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS--YRDSRGA---LVATDKVEK  590

Query  595  RDDKGRIVKAVDAEGHELVYAGMSKMSKSKNNGIDPQVMVEKYGADTVRLFMMFASPAEM  654
            RD  G +     +E  E    + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P + 
Sbjct  591  RD--GSFFHVETGEELE---QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  655  TLEWQESGVEGANRFLKRVWRLAFDHTAKGAVKPLDIASLTEEQKSLRRDLHKTIAKVTD  714
            ++ W E G+EG+ +FL RV RL         +   +I+   E+  +L +  + T+  VT+
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRL---------ITTKEITE--ENSGALDKVYNETVKAVTE  694

Query  715  DVGRRQTFNTAIAAVMELMNKLGRAPQETEQDRALMQEALLAVVRMLYPFTPHVCFSLWQ  774
            +V++ + FNTAIA +M ++N        ++++  L  +   + V+++ PF+PH+   LWQ
Sbjct  695  QVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  775  ALGGEGD-IDTAPWPIADEQAMVEDSKLVVVQVNGKVRGRITVPADATEQQVRERAGQEH  833
            AL + G+ I   PWP  DE  +VE+   +VVQ++GKV++++ V+ D + ++++E A  ++
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  834  LVAKYLDGVTVRKVIYVPGKLLNLVV  859
             V   + G  + KVI VP KL+N+V+
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVI  832

998) leuS in NC_017160


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  551 bits (2081),  Expect = 6e-158, Method: Compositional matrix adjust.
 Identities = 357/866 (42%), Positives = 552/866 (64%), Gaps = 48/866 (5%)

Query  5    YRPEDIETQVQLHWQEKQTFKVTEDASKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIS  63
            Y    IE + Q  W +++TFK   DASK K+Y L M+PYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIEYMKNQLKLLGFGYDWDR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NI   K Q++ LGF+YDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EIATCKPDYYRWEQWFFTKLYEKGMVYKKTSAVNWCPHDLTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W QW+FTKLYEKG+ Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITDYAEQLLNDLDTLESWPEQVKTMQRNWIGRSEGVDIVFDVVDSEEK  242
            V RK + QW +KIT YAE+LL+DL+ ++ WPE +K MQRNWIG+S G ++ F V D++  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LSVYTTRPDTFMGVTYVAVAAGHPLSLQAAATNPALADFVAECRNTKVAEAEMA----TM  298
            ++V+TTRPDT+ G TY  +A+ H+L    A T +  A+ VA+ +      +++A    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALV--DAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  299  EKKGMATGLYAIHPLTGEKLPIWAANFVLMDYGTGAVMAVPGHDARDWEFATKYNLPIKP  358
            EK G+ TG YAI+P+ G  +P+W A++VL  YGTGA+MAVP+HD RDWEFA ++NL I P
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VILAADGSEPDLSQEAMTEKGTLFNSGEFDGLNHEDGFNAIADKLVALGVGQRKVNYRLR  418
            V+ +++  E+ ++++++  ++ +     +DGL+   ++  + + L A GVG+ +V YRLR
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDF-----LDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  419  DWGVSRQRYWGAPIPMVTLEDGTVVPTPEDQLPVILP--EDVVMDGIS-SPIKADPEWAK  475
            DW  SRQRYWG PIP++  EDGT  + PE +LP++LP   D+   G + SP+    +W  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  476  TT-VNGIPGLRETDTFDTFMESSWYYARYTCPQYDDGMLDPAAANYWLPVDQYVGGIEHA  534
             T  +G+ G RET+T      SSWYY RY  P+  + + D    + WLPVD YVGG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  535  IMHLMYFRFFHKLLRDAGLVDSDEPAKRLLCQGMVLADAFYYTGNNGERIWVSPVDAIVE  594
            ++HL+Y RF HK+L D G+V + EP ++L+ QGM+L+ +  Y ++ G    + + D +  
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS--YRDSRGA---LVATDKVEK  590

Query  595  RDDKGRIVKAVDAEGHELVYAGMSKMSKSKNNGIDPQVMVEKYGADTVRLFMMFASPAEM  654
            RD  G +     +E  E    + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P + 
Sbjct  591  RD--GSFFHVETGEELE---QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  655  TLEWQESGVEGANRFLKRVWRLAFDHTAKGAVKPLDIASLTEEQKSLRRDLHKTIAKVTD  714
            ++ W E G+EG+ +FL RV RL         +   +I+   E+  +L +  + T+  VT+
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRL---------ITTKEITE--ENSGALDKVYNETVKAVTE  694

Query  715  DVGRRQTFNTAIAAVMELMNKLGRAPQETEQDRALMQEALLAVVRMLYPFTPHVCFSLWQ  774
            +V++ + FNTAIA +M ++N        ++++  L  +   + V+++ PF+PH+   LWQ
Sbjct  695  QVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  775  ALGGEGD-IDTAPWPIADEQAMVEDSKLVVVQVNGKVRGRITVPADATEQQVRERAGQEH  833
            AL + G+ I   PWP  DE  +VE+   +VVQ++GKV++++ V+ D + ++++E A  ++
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  834  LVAKYLDGVTVRKVIYVPGKLLNLVV  859
             V   + G  + KVI VP KL+N+V+
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVI  832

999) leuS in NC_004088


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  551 bits (2081),  Expect = 6e-158, Method: Compositional matrix adjust.
 Identities = 357/866 (42%), Positives = 552/866 (64%), Gaps = 48/866 (5%)

Query  5    YRPEDIETQVQLHWQEKQTFKVTEDASKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIS  63
            Y    IE + Q  W +++TFK   DASK K+Y L M+PYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIEYMKNQLKLLGFGYDWDR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NI   K Q++ LGF+YDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EIATCKPDYYRWEQWFFTKLYEKGMVYKKTSAVNWCPHDLTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W QW+FTKLYEKG+ Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITDYAEQLLNDLDTLESWPEQVKTMQRNWIGRSEGVDIVFDVVDSEEK  242
            V RK + QW +KIT YAE+LL+DL+ ++ WPE +K MQRNWIG+S G ++ F V D++  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LSVYTTRPDTFMGVTYVAVAAGHPLSLQAAATNPALADFVAECRNTKVAEAEMA----TM  298
            ++V+TTRPDT+ G TY  +A+ H+L    A T +  A+ VA+ +      +++A    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALV--DAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  299  EKKGMATGLYAIHPLTGEKLPIWAANFVLMDYGTGAVMAVPGHDARDWEFATKYNLPIKP  358
            EK G+ TG YAI+P+ G  +P+W A++VL  YGTGA+MAVP+HD RDWEFA ++NL I P
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VILAADGSEPDLSQEAMTEKGTLFNSGEFDGLNHEDGFNAIADKLVALGVGQRKVNYRLR  418
            V+ +++  E+ ++++++  ++ +     +DGL+   ++  + + L A GVG+ +V YRLR
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDF-----LDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  419  DWGVSRQRYWGAPIPMVTLEDGTVVPTPEDQLPVILP--EDVVMDGIS-SPIKADPEWAK  475
            DW  SRQRYWG PIP++  EDGT  + PE +LP++LP   D+   G + SP+    +W  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  476  TT-VNGIPGLRETDTFDTFMESSWYYARYTCPQYDDGMLDPAAANYWLPVDQYVGGIEHA  534
             T  +G+ G RET+T      SSWYY RY  P+  + + D    + WLPVD YVGG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  535  IMHLMYFRFFHKLLRDAGLVDSDEPAKRLLCQGMVLADAFYYTGNNGERIWVSPVDAIVE  594
            ++HL+Y RF HK+L D G+V + EP ++L+ QGM+L+ +  Y ++ G    + + D +  
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS--YRDSRGA---LVATDKVEK  590

Query  595  RDDKGRIVKAVDAEGHELVYAGMSKMSKSKNNGIDPQVMVEKYGADTVRLFMMFASPAEM  654
            RD  G +     +E  E    + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P + 
Sbjct  591  RD--GSFFHVETGEELE---QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  655  TLEWQESGVEGANRFLKRVWRLAFDHTAKGAVKPLDIASLTEEQKSLRRDLHKTIAKVTD  714
            ++ W E G+EG+ +FL RV RL         +   +I+   E+  +L +  + T+  VT+
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRL---------ITTKEITE--ENSGALDKVYNETVKAVTE  694

Query  715  DVGRRQTFNTAIAAVMELMNKLGRAPQETEQDRALMQEALLAVVRMLYPFTPHVCFSLWQ  774
            +V++ + FNTAIA +M ++N        ++++  L  +   + V+++ PF+PH+   LWQ
Sbjct  695  QVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  775  ALGGEGD-IDTAPWPIADEQAMVEDSKLVVVQVNGKVRGRITVPADATEQQVRERAGQEH  833
            AL + G+ I   PWP  DE  +VE+   +VVQ++GKV++++ V+ D + ++++E A  ++
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  834  LVAKYLDGVTVRKVIYVPGKLLNLVV  859
             V   + G  + KVI VP KL+N+V+
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVI  832

1000) leuS in NC_008149


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  551 bits (2081),  Expect = 6e-158, Method: Compositional matrix adjust.
 Identities = 357/866 (42%), Positives = 552/866 (64%), Gaps = 48/866 (5%)

Query  5    YRPEDIETQVQLHWQEKQTFKVTEDASKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIS  63
            Y    IE + Q  W +++TFK   DASK K+Y L M+PYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIEYMKNQLKLLGFGYDWDR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NI   K Q++ LGF+YDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EIATCKPDYYRWEQWFFTKLYEKGMVYKKTSAVNWCPHDLTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W QW+FTKLYEKG+ Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITDYAEQLLNDLDTLESWPEQVKTMQRNWIGRSEGVDIVFDVVDSEEK  242
            V RK + QW +KIT YAE+LL+DL+ ++ WPE +K MQRNWIG+S G ++ F V D++  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LSVYTTRPDTFMGVTYVAVAAGHPLSLQAAATNPALADFVAECRNTKVAEAEMA----TM  298
            ++V+TTRPDT+ G TY  +A+ H+L    A T +  A+ VA+ +      +++A    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALV--DAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  299  EKKGMATGLYAIHPLTGEKLPIWAANFVLMDYGTGAVMAVPGHDARDWEFATKYNLPIKP  358
            EK G+ TG YAI+P+ G  +P+W A++VL  YGTGA+MAVP+HD RDWEFA ++NL I P
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VILAADGSEPDLSQEAMTEKGTLFNSGEFDGLNHEDGFNAIADKLVALGVGQRKVNYRLR  418
            V+ +++  E+ ++++++  ++ +     +DGL+   ++  + + L A GVG+ +V YRLR
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDF-----LDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  419  DWGVSRQRYWGAPIPMVTLEDGTVVPTPEDQLPVILP--EDVVMDGIS-SPIKADPEWAK  475
            DW  SRQRYWG PIP++  EDGT  + PE +LP++LP   D+   G + SP+    +W  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  476  TT-VNGIPGLRETDTFDTFMESSWYYARYTCPQYDDGMLDPAAANYWLPVDQYVGGIEHA  534
             T  +G+ G RET+T      SSWYY RY  P+  + + D    + WLPVD YVGG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  535  IMHLMYFRFFHKLLRDAGLVDSDEPAKRLLCQGMVLADAFYYTGNNGERIWVSPVDAIVE  594
            ++HL+Y RF HK+L D G+V + EP ++L+ QGM+L+ +  Y ++ G    + + D +  
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS--YRDSRGA---LVATDKVEK  590

Query  595  RDDKGRIVKAVDAEGHELVYAGMSKMSKSKNNGIDPQVMVEKYGADTVRLFMMFASPAEM  654
            RD  G +     +E  E    + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P + 
Sbjct  591  RD--GSFFHVETGEELE---QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  655  TLEWQESGVEGANRFLKRVWRLAFDHTAKGAVKPLDIASLTEEQKSLRRDLHKTIAKVTD  714
            ++ W E G+EG+ +FL RV RL         +   +I+   E+  +L +  + T+  VT+
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRL---------ITTKEITE--ENSGALDKVYNETVKAVTE  694

Query  715  DVGRRQTFNTAIAAVMELMNKLGRAPQETEQDRALMQEALLAVVRMLYPFTPHVCFSLWQ  774
            +V++ + FNTAIA +M ++N        ++++  L  +   + V+++ PF+PH+   LWQ
Sbjct  695  QVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  775  ALGGEGD-IDTAPWPIADEQAMVEDSKLVVVQVNGKVRGRITVPADATEQQVRERAGQEH  833
            AL + G+ I   PWP  DE  +VE+   +VVQ++GKV++++ V+ D + ++++E A  ++
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  834  LVAKYLDGVTVRKVIYVPGKLLNLVV  859
             V   + G  + KVI VP KL+N+V+
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVI  832

1001) leuS in NC_009381


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  551 bits (2081),  Expect = 6e-158, Method: Compositional matrix adjust.
 Identities = 357/866 (42%), Positives = 552/866 (64%), Gaps = 48/866 (5%)

Query  5    YRPEDIETQVQLHWQEKQTFKVTEDASKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIS  63
            Y    IE + Q  W +++TFK   DASK K+Y L M+PYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIEYMKNQLKLLGFGYDWDR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NI   K Q++ LGF+YDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EIATCKPDYYRWEQWFFTKLYEKGMVYKKTSAVNWCPHDLTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W QW+FTKLYEKG+ Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITDYAEQLLNDLDTLESWPEQVKTMQRNWIGRSEGVDIVFDVVDSEEK  242
            V RK + QW +KIT YAE+LL+DL+ ++ WPE +K MQRNWIG+S G ++ F V D++  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LSVYTTRPDTFMGVTYVAVAAGHPLSLQAAATNPALADFVAECRNTKVAEAEMA----TM  298
            ++V+TTRPDT+ G TY  +A+ H+L    A T +  A+ VA+ +      +++A    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALV--DAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  299  EKKGMATGLYAIHPLTGEKLPIWAANFVLMDYGTGAVMAVPGHDARDWEFATKYNLPIKP  358
            EK G+ TG YAI+P+ G  +P+W A++VL  YGTGA+MAVP+HD RDWEFA ++NL I P
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VILAADGSEPDLSQEAMTEKGTLFNSGEFDGLNHEDGFNAIADKLVALGVGQRKVNYRLR  418
            V+ +++  E+ ++++++  ++ +     +DGL+   ++  + + L A GVG+ +V YRLR
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDF-----LDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  419  DWGVSRQRYWGAPIPMVTLEDGTVVPTPEDQLPVILP--EDVVMDGIS-SPIKADPEWAK  475
            DW  SRQRYWG PIP++  EDGT  + PE +LP++LP   D+   G + SP+    +W  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  476  TT-VNGIPGLRETDTFDTFMESSWYYARYTCPQYDDGMLDPAAANYWLPVDQYVGGIEHA  534
             T  +G+ G RET+T      SSWYY RY  P+  + + D    + WLPVD YVGG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  535  IMHLMYFRFFHKLLRDAGLVDSDEPAKRLLCQGMVLADAFYYTGNNGERIWVSPVDAIVE  594
            ++HL+Y RF HK+L D G+V + EP ++L+ QGM+L+ +  Y ++ G    + + D +  
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS--YRDSRGA---LVATDKVEK  590

Query  595  RDDKGRIVKAVDAEGHELVYAGMSKMSKSKNNGIDPQVMVEKYGADTVRLFMMFASPAEM  654
            RD  G +     +E  E    + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P + 
Sbjct  591  RD--GSFFHVETGEELE---QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  655  TLEWQESGVEGANRFLKRVWRLAFDHTAKGAVKPLDIASLTEEQKSLRRDLHKTIAKVTD  714
            ++ W E G+EG+ +FL RV RL         +   +I+   E+  +L +  + T+  VT+
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRL---------ITTKEITE--ENSGALDKVYNETVKAVTE  694

Query  715  DVGRRQTFNTAIAAVMELMNKLGRAPQETEQDRALMQEALLAVVRMLYPFTPHVCFSLWQ  774
            +V++ + FNTAIA +M ++N        ++++  L  +   + V+++ PF+PH+   LWQ
Sbjct  695  QVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  775  ALGGEGD-IDTAPWPIADEQAMVEDSKLVVVQVNGKVRGRITVPADATEQQVRERAGQEH  833
            AL + G+ I   PWP  DE  +VE+   +VVQ++GKV++++ V+ D + ++++E A  ++
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  834  LVAKYLDGVTVRKVIYVPGKLLNLVV  859
             V   + G  + KVI VP KL+N+V+
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVI  832

1002) leuS in NC_014029


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  551 bits (2081),  Expect = 6e-158, Method: Compositional matrix adjust.
 Identities = 357/866 (42%), Positives = 552/866 (64%), Gaps = 48/866 (5%)

Query  5    YRPEDIETQVQLHWQEKQTFKVTEDASKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIS  63
            Y    IE + Q  W +++TFK   DASK K+Y L M+PYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIEYMKNQLKLLGFGYDWDR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NI   K Q++ LGF+YDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EIATCKPDYYRWEQWFFTKLYEKGMVYKKTSAVNWCPHDLTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W QW+FTKLYEKG+ Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITDYAEQLLNDLDTLESWPEQVKTMQRNWIGRSEGVDIVFDVVDSEEK  242
            V RK + QW +KIT YAE+LL+DL+ ++ WPE +K MQRNWIG+S G ++ F V D++  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LSVYTTRPDTFMGVTYVAVAAGHPLSLQAAATNPALADFVAECRNTKVAEAEMA----TM  298
            ++V+TTRPDT+ G TY  +A+ H+L    A T +  A+ VA+ +      +++A    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALV--DAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  299  EKKGMATGLYAIHPLTGEKLPIWAANFVLMDYGTGAVMAVPGHDARDWEFATKYNLPIKP  358
            EK G+ TG YAI+P+ G  +P+W A++VL  YGTGA+MAVP+HD RDWEFA ++NL I P
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VILAADGSEPDLSQEAMTEKGTLFNSGEFDGLNHEDGFNAIADKLVALGVGQRKVNYRLR  418
            V+ +++  E+ ++++++  ++ +     +DGL+   ++  + + L A GVG+ +V YRLR
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDF-----LDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  419  DWGVSRQRYWGAPIPMVTLEDGTVVPTPEDQLPVILP--EDVVMDGIS-SPIKADPEWAK  475
            DW  SRQRYWG PIP++  EDGT  + PE +LP++LP   D+   G + SP+    +W  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  476  TT-VNGIPGLRETDTFDTFMESSWYYARYTCPQYDDGMLDPAAANYWLPVDQYVGGIEHA  534
             T  +G+ G RET+T      SSWYY RY  P+  + + D    + WLPVD YVGG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  535  IMHLMYFRFFHKLLRDAGLVDSDEPAKRLLCQGMVLADAFYYTGNNGERIWVSPVDAIVE  594
            ++HL+Y RF HK+L D G+V + EP ++L+ QGM+L+ +  Y ++ G    + + D +  
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS--YRDSRGA---LVATDKVEK  590

Query  595  RDDKGRIVKAVDAEGHELVYAGMSKMSKSKNNGIDPQVMVEKYGADTVRLFMMFASPAEM  654
            RD  G +     +E  E    + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P + 
Sbjct  591  RD--GSFFHVETGEELE---QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  655  TLEWQESGVEGANRFLKRVWRLAFDHTAKGAVKPLDIASLTEEQKSLRRDLHKTIAKVTD  714
            ++ W E G+EG+ +FL RV RL         +   +I+   E+  +L +  + T+  VT+
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRL---------ITTKEITE--ENSGALDKVYNETVKAVTE  694

Query  715  DVGRRQTFNTAIAAVMELMNKLGRAPQETEQDRALMQEALLAVVRMLYPFTPHVCFSLWQ  774
            +V++ + FNTAIA +M ++N        ++++  L  +   + V+++ PF+PH+   LWQ
Sbjct  695  QVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  775  ALGGEGD-IDTAPWPIADEQAMVEDSKLVVVQVNGKVRGRITVPADATEQQVRERAGQEH  833
            AL + G+ I   PWP  DE  +VE+   +VVQ++GKV++++ V+ D + ++++E A  ++
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  834  LVAKYLDGVTVRKVIYVPGKLLNLVV  859
             V   + G  + KVI VP KL+N+V+
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVI  832

1003) leuS in NC_009708


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  551 bits (2081),  Expect = 6e-158, Method: Compositional matrix adjust.
 Identities = 357/866 (42%), Positives = 552/866 (64%), Gaps = 48/866 (5%)

Query  5    YRPEDIETQVQLHWQEKQTFKVTEDASKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIS  63
            Y    IE + Q  W +++TFK   DASK K+Y L M+PYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIEYMKNQLKLLGFGYDWDR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NI   K Q++ LGF+YDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EIATCKPDYYRWEQWFFTKLYEKGMVYKKTSAVNWCPHDLTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W QW+FTKLYEKG+ Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITDYAEQLLNDLDTLESWPEQVKTMQRNWIGRSEGVDIVFDVVDSEEK  242
            V RK + QW +KIT YAE+LL+DL+ ++ WPE +K MQRNWIG+S G ++ F V D++  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LSVYTTRPDTFMGVTYVAVAAGHPLSLQAAATNPALADFVAECRNTKVAEAEMA----TM  298
            ++V+TTRPDT+ G TY  +A+ H+L    A T +  A+ VA+ +      +++A    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALV--DAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  299  EKKGMATGLYAIHPLTGEKLPIWAANFVLMDYGTGAVMAVPGHDARDWEFATKYNLPIKP  358
            EK G+ TG YAI+P+ G  +P+W A++VL  YGTGA+MAVP+HD RDWEFA ++NL I P
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VILAADGSEPDLSQEAMTEKGTLFNSGEFDGLNHEDGFNAIADKLVALGVGQRKVNYRLR  418
            V+ +++  E+ ++++++  ++ +     +DGL+   ++  + + L A GVG+ +V YRLR
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDF-----LDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  419  DWGVSRQRYWGAPIPMVTLEDGTVVPTPEDQLPVILP--EDVVMDGIS-SPIKADPEWAK  475
            DW  SRQRYWG PIP++  EDGT  + PE +LP++LP   D+   G + SP+    +W  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  476  TT-VNGIPGLRETDTFDTFMESSWYYARYTCPQYDDGMLDPAAANYWLPVDQYVGGIEHA  534
             T  +G+ G RET+T      SSWYY RY  P+  + + D    + WLPVD YVGG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  535  IMHLMYFRFFHKLLRDAGLVDSDEPAKRLLCQGMVLADAFYYTGNNGERIWVSPVDAIVE  594
            ++HL+Y RF HK+L D G+V + EP ++L+ QGM+L+ +  Y ++ G    + + D +  
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS--YRDSRGA---LVATDKVEK  590

Query  595  RDDKGRIVKAVDAEGHELVYAGMSKMSKSKNNGIDPQVMVEKYGADTVRLFMMFASPAEM  654
            RD  G +     +E  E    + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P + 
Sbjct  591  RD--GSFFHVETGEELE---QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  655  TLEWQESGVEGANRFLKRVWRLAFDHTAKGAVKPLDIASLTEEQKSLRRDLHKTIAKVTD  714
            ++ W E G+EG+ +FL RV RL         +   +I+   E+  +L +  + T+  VT+
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRL---------ITTKEITE--ENSGALDKVYNETVKAVTE  694

Query  715  DVGRRQTFNTAIAAVMELMNKLGRAPQETEQDRALMQEALLAVVRMLYPFTPHVCFSLWQ  774
            +V++ + FNTAIA +M ++N        ++++  L  +   + V+++ PF+PH+   LWQ
Sbjct  695  QVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  775  ALGGEGD-IDTAPWPIADEQAMVEDSKLVVVQVNGKVRGRITVPADATEQQVRERAGQEH  833
            AL + G+ I   PWP  DE  +VE+   +VVQ++GKV++++ V+ D + ++++E A  ++
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  834  LVAKYLDGVTVRKVIYVPGKLLNLVV  859
             V   + G  + KVI VP KL+N+V+
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVI  832

1004) leuS in NC_006155


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  551 bits (2081),  Expect = 6e-158, Method: Compositional matrix adjust.
 Identities = 357/866 (42%), Positives = 552/866 (64%), Gaps = 48/866 (5%)

Query  5    YRPEDIETQVQLHWQEKQTFKVTEDASKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIS  63
            Y    IE + Q  W +++TFK   DASK K+Y L M+PYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIEYMKNQLKLLGFGYDWDR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NI   K Q++ LGF+YDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EIATCKPDYYRWEQWFFTKLYEKGMVYKKTSAVNWCPHDLTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W QW+FTKLYEKG+ Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITDYAEQLLNDLDTLESWPEQVKTMQRNWIGRSEGVDIVFDVVDSEEK  242
            V RK + QW +KIT YAE+LL+DL+ ++ WPE +K MQRNWIG+S G ++ F V D++  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LSVYTTRPDTFMGVTYVAVAAGHPLSLQAAATNPALADFVAECRNTKVAEAEMA----TM  298
            ++V+TTRPDT+ G TY  +A+ H+L    A T +  A+ VA+ +      +++A    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALV--DAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  299  EKKGMATGLYAIHPLTGEKLPIWAANFVLMDYGTGAVMAVPGHDARDWEFATKYNLPIKP  358
            EK G+ TG YAI+P+ G  +P+W A++VL  YGTGA+MAVP+HD RDWEFA ++NL I P
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VILAADGSEPDLSQEAMTEKGTLFNSGEFDGLNHEDGFNAIADKLVALGVGQRKVNYRLR  418
            V+ +++  E+ ++++++  ++ +     +DGL+   ++  + + L A GVG+ +V YRLR
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDF-----LDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  419  DWGVSRQRYWGAPIPMVTLEDGTVVPTPEDQLPVILP--EDVVMDGIS-SPIKADPEWAK  475
            DW  SRQRYWG PIP++  EDGT  + PE +LP++LP   D+   G + SP+    +W  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  476  TT-VNGIPGLRETDTFDTFMESSWYYARYTCPQYDDGMLDPAAANYWLPVDQYVGGIEHA  534
             T  +G+ G RET+T      SSWYY RY  P+  + + D    + WLPVD YVGG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  535  IMHLMYFRFFHKLLRDAGLVDSDEPAKRLLCQGMVLADAFYYTGNNGERIWVSPVDAIVE  594
            ++HL+Y RF HK+L D G+V + EP ++L+ QGM+L+ +  Y ++ G    + + D +  
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS--YRDSRGA---LVATDKVEK  590

Query  595  RDDKGRIVKAVDAEGHELVYAGMSKMSKSKNNGIDPQVMVEKYGADTVRLFMMFASPAEM  654
            RD  G +     +E  E    + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P + 
Sbjct  591  RD--GSFFHVETGEELE---QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  655  TLEWQESGVEGANRFLKRVWRLAFDHTAKGAVKPLDIASLTEEQKSLRRDLHKTIAKVTD  714
            ++ W E G+EG+ +FL RV RL         +   +I+   E+  +L +  + T+  VT+
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRL---------ITTKEITE--ENSGALDKVYNETVKAVTE  694

Query  715  DVGRRQTFNTAIAAVMELMNKLGRAPQETEQDRALMQEALLAVVRMLYPFTPHVCFSLWQ  774
            +V++ + FNTAIA +M ++N        ++++  L  +   + V+++ PF+PH+   LWQ
Sbjct  695  QVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  775  ALGGEGD-IDTAPWPIADEQAMVEDSKLVVVQVNGKVRGRITVPADATEQQVRERAGQEH  833
            AL + G+ I   PWP  DE  +VE+   +VVQ++GKV++++ V+ D + ++++E A  ++
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  834  LVAKYLDGVTVRKVIYVPGKLLNLVV  859
             V   + G  + KVI VP KL+N+V+
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVI  832

1005) leuS in NC_010634


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  551 bits (2081),  Expect = 6e-158, Method: Compositional matrix adjust.
 Identities = 357/866 (42%), Positives = 552/866 (64%), Gaps = 48/866 (5%)

Query  5    YRPEDIETQVQLHWQEKQTFKVTEDASKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIS  63
            Y    IE + Q  W +++TFK   DASK K+Y L M+PYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIEYMKNQLKLLGFGYDWDR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NI   K Q++ LGF+YDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EIATCKPDYYRWEQWFFTKLYEKGMVYKKTSAVNWCPHDLTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W QW+FTKLYEKG+ Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITDYAEQLLNDLDTLESWPEQVKTMQRNWIGRSEGVDIVFDVVDSEEK  242
            V RK + QW +KIT YAE+LL+DL+ ++ WPE +K MQRNWIG+S G ++ F V D++  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LSVYTTRPDTFMGVTYVAVAAGHPLSLQAAATNPALADFVAECRNTKVAEAEMA----TM  298
            ++V+TTRPDT+ G TY  +A+ H+L    A T +  A+ VA+ +      +++A    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALV--DAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  299  EKKGMATGLYAIHPLTGEKLPIWAANFVLMDYGTGAVMAVPGHDARDWEFATKYNLPIKP  358
            EK G+ TG YAI+P+ G  +P+W A++VL  YGTGA+MAVP+HD RDWEFA ++NL I P
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VILAADGSEPDLSQEAMTEKGTLFNSGEFDGLNHEDGFNAIADKLVALGVGQRKVNYRLR  418
            V+ +++  E+ ++++++  ++ +     +DGL+   ++  + + L A GVG+ +V YRLR
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDF-----LDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  419  DWGVSRQRYWGAPIPMVTLEDGTVVPTPEDQLPVILP--EDVVMDGIS-SPIKADPEWAK  475
            DW  SRQRYWG PIP++  EDGT  + PE +LP++LP   D+   G + SP+    +W  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  476  TT-VNGIPGLRETDTFDTFMESSWYYARYTCPQYDDGMLDPAAANYWLPVDQYVGGIEHA  534
             T  +G+ G RET+T      SSWYY RY  P+  + + D    + WLPVD YVGG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  535  IMHLMYFRFFHKLLRDAGLVDSDEPAKRLLCQGMVLADAFYYTGNNGERIWVSPVDAIVE  594
            ++HL+Y RF HK+L D G+V + EP ++L+ QGM+L+ +  Y ++ G    + + D +  
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS--YRDSRGA---LVATDKVEK  590

Query  595  RDDKGRIVKAVDAEGHELVYAGMSKMSKSKNNGIDPQVMVEKYGADTVRLFMMFASPAEM  654
            RD  G +     +E  E    + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P + 
Sbjct  591  RD--GSFFHVETGEELE---QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  655  TLEWQESGVEGANRFLKRVWRLAFDHTAKGAVKPLDIASLTEEQKSLRRDLHKTIAKVTD  714
            ++ W E G+EG+ +FL RV RL         +   +I+   E+  +L +  + T+  VT+
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRL---------ITTKEITE--ENSGALDKVYNETVKAVTE  694

Query  715  DVGRRQTFNTAIAAVMELMNKLGRAPQETEQDRALMQEALLAVVRMLYPFTPHVCFSLWQ  774
            +V++ + FNTAIA +M ++N        ++++  L  +   + V+++ PF+PH+   LWQ
Sbjct  695  QVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  775  ALGGEGD-IDTAPWPIADEQAMVEDSKLVVVQVNGKVRGRITVPADATEQQVRERAGQEH  833
            AL + G+ I   PWP  DE  +VE+   +VVQ++GKV++++ V+ D + ++++E A  ++
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  834  LVAKYLDGVTVRKVIYVPGKLLNLVV  859
             V   + G  + KVI VP KL+N+V+
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVI  832

1006) leuS in NC_010465


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  551 bits (2081),  Expect = 6e-158, Method: Compositional matrix adjust.
 Identities = 357/866 (42%), Positives = 552/866 (64%), Gaps = 48/866 (5%)

Query  5    YRPEDIETQVQLHWQEKQTFKVTEDASKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIS  63
            Y    IE + Q  W +++TFK   DASK K+Y L M+PYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIEYMKNQLKLLGFGYDWDR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NI   K Q++ LGF+YDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EIATCKPDYYRWEQWFFTKLYEKGMVYKKTSAVNWCPHDLTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W QW+FTKLYEKG+ Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITDYAEQLLNDLDTLESWPEQVKTMQRNWIGRSEGVDIIFDVVDSEEK  242
            V RK + QW +KIT YAE+LL+DL+ ++ WPE +K MQRNWIG+S G ++ F V D++  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LSVYTTRPDTFMGVTYVAVAAGHPLSLQAAATNPALADFVAECRNTKVAEAEMA----TM  298
            ++V+TTRPDT+ G TY  +A+ H+L    A T +  A+ VA+ +      +++A    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALV--DAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  299  EKKGMATGLYAIHPLTGEKLPIWAANFVLMDYGTGAVMAVPGHDARDWEFATKYNLPIKP  358
            EK G+ TG YAI+P+ G  +P+W A++VL  YGTGA+MAVP+HD RDWEFA ++NL I P
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VILAADGSEPDLSQEAMTEKGTLFNSGEFDGLNHEDGFNAIADKLVALGVGQRKVNYRLR  418
            V+ +++  E+ ++++++  ++ +     +DGL+   ++  + + L A GVG+ +V YRLR
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDF-----LDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  419  DWGVSRQRYWGAPIPMVTLEDGTVVPTPEDQLPVILP--EDVVMDGIS-SPIKADPEWAK  475
            DW  SRQRYWG PIP++  EDGT  + PE +LP++LP   D+   G + SP+    +W  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  476  TT-VNGIPGLRETDTFDTFMESSWYYARYTCPQYDDGMLDPAAANYWLPVDQYVGGIEHA  534
             T  +G+ G RET+T      SSWYY RY  P+  + + D    + WLPVD YVGG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  535  IMHLMYFRFFHKLLRDAGLVDSDEPAKRLLCQGMVLADAFYYTGNNGERIWVSPVDAIVE  594
            ++HL+Y RF HK+L D G+V + EP ++L+ QGM+L+ +  Y ++ G    + + D +  
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS--YRDSRGA---LVATDKVEK  590

Query  595  RDDKGRIVKAVDAEGHELVYAGMSKMSKSKNNGIDPQVMVEKYGADTVRLFMMFASPAEM  654
            RD  G +     +E  E    + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P + 
Sbjct  591  RD--GSFFHVETGEELE---QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  655  TLEWQESGVEGANRFLKRVWRLAFDHTAKGAVKPLDIASLTEEQKSLRRDLHKTIAKVTD  714
            ++ W E G+EG+ +FL RV RL         +   +I+   E+  +L +  + T+  VT+
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRL---------ITTKEITE--ENSGALDKVYNETVKAVTE  694

Query  715  DVGRRQTFNTAIAAVMELMNKLGRAPQETEQDRALMQEALLAVVRMLYPFTPHVCFSLWQ  774
            +V++ + FNTAIA +M ++N        ++++  L  +   + V+++ PF+PH+   LWQ
Sbjct  695  QVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  775  ALGGEGD-IDTAPWPIADEQAMVEDSKLVVVQVNGKVRGRITVPADATEQQVRERAGQEH  833
            AL + G+ I   PWP  DE  +VE+   +VVQ++GKV++++ V+ D + ++++E A  ++
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  834  LVAKYLDGVTVRKVIYVPGKLLNLVV  859
             V   + G  + KVI VP KL+N+V+
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVI  832

1007) leuS in NC_006958


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  551 bits (2081),  Expect = 7e-158, Method: Compositional matrix adjust.
 Identities = 355/739 (49%), Positives = 503/739 (69%), Gaps = 59/739 (7%)

Query  232  LVYRSNSTVNWCPGLGTVLANEEVTADGRSERGNFPVFRKNLSQWMMRITAYSDRLIDDL  291
            L Y ++  VNW   LGT +ANEEV +DG SERG +PV RK + QWM++ITAY++RL++DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  292  ELLDWTEKVKSMQRNWIGRSRGAEVDFSAE--GETVTVFTTRPDTLFGATYMVLAPEHEL  349
            E +DW E +K MQRNWIG+S GA+V F     +   TVFTTRPDTLFGATY VLAPEH L
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  350  VDVLLEKAGSYEGVDARWTNGQASPAEAVAAYRASIAAKSDLERQE-NKEKTGVFLGVYA  408
            VD +                  +  AEAVA Y+   + KSDL R +  KEKTGV  G YA
Sbjct  268  VDAI----------------TTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYA  311

Query  409  TNPVNGDQITVFIADYVLTGYGTGAIMAVPAHDERDYEFATVLGLPIKEVVAGGNIEEAA  468
             NPVNG ++ V IADYVL++YGTGAIMAVPAHDERD EFA  + L I  V+ GGN+EEAA
Sbjct  312  INPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEAA  371

Query  469  FTESGEAVNSANDNGLDINGLAKDEAIAKTIEWLEEKELGRGTIQYKLRDWLFARQRYWG  528
            FTE G  +NS       ++GL K  AIAK +EWLE   +G   + Y+LRDWLF+RQRYWG
Sbjct  372  FTEDGLHINSDF-----LDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWG  426

Query  529  EPFPIVYDENGQAHALPDSMLPVELPEVEDYKPVSFdpedadsepsppLAKAREWVEVEL  588
            EP+PI+  E+G + A+P+S LP+ LP   D +P +           +PLA+  +W+EV  
Sbjct  427  EPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSG--------TGESPLANVTDWLEVTR  478

Query  589  DLGDGKKKYTRDTNVMPQWAGSSWYQLRYVDPSNDEQFCNIENERYWTGPRPETHGPNDP  648
            + G   +   R+TN MPQWAGSSWY LRY+DP N E++ + E  + W             
Sbjct  479  EDGVKGR---RETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWL------------  523

Query  649  GGVDLYVGGVEHAVLHLLYARFWHKVLFDLGHVSSKEPYRRLYNQGYIQAFAYTDSRGVY  708
              VD+YVGG EHAVLHLLYARFWHKVL+DLG V++KEP+++L+NQG I + +Y DSRG  
Sbjct  524  -PVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGAL  582

Query  709  VPADDVEEKDGKFFY--QGEEVNQEYGKMGKSLKNAVAPDDICNNFGADTLRVYEMAMGP  766
            V++D VE +DG FF    GEE++Q  +KM+KSLKN V PDD+ +++GADTLRVYEM MGP
Sbjct  583  VATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGP  642

Query  767  LDTSRPWATKDVVGAQRFLQRLWRLVVDENTGEVLTRDEVLTDDDNKQLHRTIAGVRDDY  826
            LD+S +W+  ++ G+++FL+R+ RL+   +  E       L    +K  + T+ +V ++ 
Sbjct  643  LDASIAWSEEGLEGSRKFLDRVYRLITTKEITE--ENSGAL----DKVYNETVKAVTEQV  696

Query  827  TNLRVNTVVAKLIEYVNYLTKTYPDTIPAGAVLPLIVMVSPIAPHIAEELWKKL-GHDDT  885
             +++ NT +A+L+ +VN   K   D + ++    ++ +++P+APH++EELW+ L + +++
Sbjct  697  DQMKFNTAIAQLMVFVNAANKE--DKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGES  754

Query  886  VTYEPFPTFEEKWLTDDEIELPVQVNGKVRGRITVAADASQEQVIEAALADEKVQEQISG  945
            ++Y P P+++E  L ++++E+ VQ++GKV++++ VA D S+E++ E ALA+EKVQ +I+G
Sbjct  755  ISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAG  814

Query  946  KNLIKQIVVPGRMVNLVVK  964
            K++IK I VP ++VN+V+K
Sbjct  815  KDIIKVIAVPNKLVNIVIK  833


 Score =  141 bits (519),  Expect = 2e-34, Method: Compositional matrix adjust.
 Identities = 79/149 (54%), Positives = 104/149 (70%), Gaps = 11/149 (7%)

Query  35   IEGEWQNYWTDNGTFNAPNPVGDLAPADGKALPEDKLFVQDMFPYPSGAGLHVGHPLGYI  94
            IE  WQ +W+DN TF++           G   +  K++  DMFPYPSGAGLHVGHP GY 
Sbjct  9    IEPKWQAFWADNHTFKT-----------GTDASKPKFYALDMFPYPSGAGLHVGHPEGYT  57

Query  95   ATDVFARYNRMLGKNVLHTLGYDAFGLPAEQYAIQTGTHPRTTTMANIENMKRQLGALGL  154
            ATD+++R++R  G NVLH +G DAFGLPAEQYA++TG +P   T  NI N KRQ+ ALG+
Sbjct  58   ATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGF  117

Query  155  GHDSRRAVATTDPEFYKWTQWIFLQIFNS  183
            + D  R V TTDP++YKWTQWIF ++++ 
Sbjct  118  SYDWDREVNTTDPNYYKWTQWIFTKLYEK  146

1008) leuS in NC_018866


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  551 bits (2080),  Expect = 7e-158, Method: Compositional matrix adjust.
 Identities = 373/866 (44%), Positives = 555/866 (65%), Gaps = 76/866 (8%)

Query  5    YLFNEIESKWQKAWLENKAGKTEENNGKEKFYALAMFPYPSG-NLHMGHVRNYSIVDVIA  63
            Y    IE+KWQ  W +N + KT  + +K KFYAL MFPYPSG  LH+GH   Y+  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RFKRMQGYDVLHPIGWDAFGLPAENAAIKHQTPPAEWTWKNIANMKRQLQEMGISYDWDR  123
            RFKR QG +VLHP+GWDAFGLPAE+ A+     PAE T  NIAN KRQ++ +G+SYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVATCHPEYYRWTQWIFNQFYKHGLVYKKKAAVNWCPSCATVLANEQVV-DGACERCDTP  182
            EV T +P+YY+WTQWIF ++Y  GL Y    +VNW    +T +ANE+V+ DG+ ER + P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VTKKDLEQWFFKITDYSEQLLNDLDKLTGWPEKVKTMQRNWIGRSEGAEAKFKIEGTTDM  242
            V +K + QW +KIT Y+E+LL+DL+ + +WPE +K MQRNWIG+S GA+  FK+ +T   
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  ITVFTTRVDTIFGVSYVVLAPEHPLVTQLVKGTQYEQGVLAFIEKMKGLNEIARTSSEAE  302
            +TVFTTR DT+FG +Y VLAPEH+LV  +  + Q  ++V  +  +    +++ART    E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQ-AEAVADYKRQASLKSDLARTDLAKE  301

Query  303  KEGMFIGHYCINPLSGERIPIWIANYVLLEYGTGAVMGVPGHDERDFAFAGKYGLPIARV  362
            K G+  G Y INP++G  +P+WIA+YVL  YGTGA+M+VP+HDERD  FA ++ L I  V
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  363  ILDPKVSAADKDMPMKEAYIEDGTMVNSLDFDGLDNRTAWDRMAAKLEKLQLGERKINYR  422
            + + +V  A        A+ EDG  +NS  +DGLD+ +A  +M   LE   +G+ ++ YR
Sbjct  362  LEGGNVEEA--------AFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYR  413

Query  423  LRDWLISRQRYWGAPIPMIYCDTCGvvpvpddqlpvllpddvvFK---AGENPLTTSQSF  479
            LRDWL+SRQRYWG PIP+I  +     +VP+ +LP++LP    ++   +GE+PL+     
Sbjct  414  LRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDW  473

Query  480  VQTTCTKCGGPARRETDTMDTFMCSSWYYLRYCDPRNPDKAFDEKNTAKWMNVDQYVGGV  539
            ++ T    G  +RRET+TM     SSWYYLRY DP+N +K  DE    +W+ VD YVGG 
Sbjct  474  LEVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGA  532

Query  540  EHAILHLLYSRFFTKALRDFGYLQVDEPFANLLTQGMV----------------------  577
            EHA+LHLLY+RF  K L D+G +   EPF +L+ QGM+                      
Sbjct  533  EHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRD  592

Query  578  ------------CMDGSKMSKSKGNVVSPEEIISKYGADTARMFILFAAPPERDLEWSEQ  625
                            +KMSKS  NVV+P++++ +YGADT R++ +F +P +  + WSE+
Sbjct  593  GSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEE  652

Query  626  GVEGCYRFLNRVWRLIVQYQAALASAGNGSTARESFAELDAKAKQMRFTTHSAIRKVTND  685
            G+EG  +FL+RV RLI      ++   +G+  +                 + +++ VT++
Sbjct  653  GLEGSRKFLDRVYRLIT--TKEITEENSGALDK---------------VYNETVKAVTEQ  695

Query  686  VGSRFNFNTAISSIMELVNALYLYKEEKDANLAVAREGIETLLKILAPFAPHITEELWAE  745
            V+ + +FNTAI+ +M +VNA      +K+ +L    +    +++++APFAPH+ EELW  
Sbjct  696  VD-QMKFNTAIAQLMVFVNA-----ANKEDKL--FSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  746  L-GNTESIHKQAWPiedetalieeeitiilQVNGKVRDKVQVPAEISKEELEKMILSSEK  804
            L ++ ESI   +WP  DE+ L+E+++ I++Q++GKV+ K+ V+ ++S+EEL+ + L++EK
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  805  VKQHLEGKTVIKVITVLGKLVNIVVR  830
            V+ ++ GK +IKVI+V  KLVNIV++
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVIK  833

1009) DCF50_p2591 in NC_018867


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  551 bits (2080),  Expect = 7e-158, Method: Compositional matrix adjust.
 Identities = 373/866 (44%), Positives = 555/866 (65%), Gaps = 76/866 (8%)

Query  5    YLFNEIESKWQKAWLENKAGKTEENNGKEKFYALAMFPYPSG-NLHMGHVRNYSIVDVIA  63
            Y    IE+KWQ  W +N + KT  + +K KFYAL MFPYPSG  LH+GH   Y+  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RFKRMQGYDVLHPIGWDAFGLPAENAAIKHQTPPAEWTWKNIANMKRQLQEMGISYDWDR  123
            RFKR QG +VLHP+GWDAFGLPAE+ A+     PAE T  NIAN KRQ++ +G+SYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVATCHPEYYRWTQWIFNQFYKHGLVYKKKAAVNWCPSCATVLANEQVV-DGACERCDTP  182
            EV T +P+YY+WTQWIF ++Y  GL Y    +VNW    +T +ANE+V+ DG+ ER + P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VTKKDLEQWFFKITDYSEQLLNDLDKLTGWPEKVKTMQRNWIGRSEGAEAKFKIEGTTDM  242
            V +K + QW +KIT Y+E+LL+DL+ + +WPE +K MQRNWIG+S GA+  FK+ +T   
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  ITVFTTRVDTIFGVSYVVLAPEHPLVTQLVKGTQYEQGVLAFIEKMKGLNEIARTSSEAE  302
            +TVFTTR DT+FG +Y VLAPEH+LV  +  + Q  ++V  +  +    +++ART    E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQ-AEAVADYKRQASLKSDLARTDLAKE  301

Query  303  KEGMFIGHYCINPLSGERIPIWIANYVLLEYGTGAVMGVPGHDERDFAFAGKYGLPIARV  362
            K G+  G Y INP++G  +P+WIA+YVL  YGTGA+M+VP+HDERD  FA ++ L I  V
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  363  ILDPKVSAADKDMPMKEAYIEDGTMVNSLDFDGLDNRTAWDRMAAKLEKLQLGERKINYR  422
            + + +V  A        A+ EDG  +NS  +DGLD+ +A  +M   LE   +G+ ++ YR
Sbjct  362  LEGGNVEEA--------AFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYR  413

Query  423  LRDWLISRQRYWGAPIPMIYCDTCGvvpvpddqlpvllpddvvFK---AGENPLTTSQSF  479
            LRDWL+SRQRYWG PIP+I  +     +VP+ +LP++LP    ++   +GE+PL+     
Sbjct  414  LRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDW  473

Query  480  VQTTCTKCGGPARRETDTMDTFMCSSWYYLRYCDPRNPDKAFDEKNTAKWMNVDQYVGGV  539
            ++ T    G  +RRET+TM     SSWYYLRY DP+N +K  DE    +W+ VD YVGG 
Sbjct  474  LEVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGA  532

Query  540  EHAILHLLYSRFFTKALRDFGYLQVDEPFANLLTQGMV----------------------  577
            EHA+LHLLY+RF  K L D+G +   EPF +L+ QGM+                      
Sbjct  533  EHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRD  592

Query  578  ------------CMDGSKMSKSKGNVVSPEEIISKYGADTARMFILFAAPPERDLEWSEQ  625
                            +KMSKS  NVV+P++++ +YGADT R++ +F +P +  + WSE+
Sbjct  593  GSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEE  652

Query  626  GVEGCYRFLNRVWRLIVQYQAALASAGNGSTARESFAELDAKAKQMRFTTHSAIRKVTND  685
            G+EG  +FL+RV RLI      ++   +G+  +                 + +++ VT++
Sbjct  653  GLEGSRKFLDRVYRLIT--TKEITEENSGALDK---------------VYNETVKAVTEQ  695

Query  686  VGSRFNFNTAISSIMELVNALYLYKEEKDANLAVAREGIETLLKILAPFAPHITEELWAE  745
            V+ + +FNTAI+ +M +VNA      +K+ +L    +    +++++APFAPH+ EELW  
Sbjct  696  VD-QMKFNTAIAQLMVFVNA-----ANKEDKL--FSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  746  L-GNTESIHKQAWPiedetalieeeitiilQVNGKVRDKVQVPAEISKEELEKMILSSEK  804
            L ++ ESI   +WP  DE+ L+E+++ I++Q++GKV+ K+ V+ ++S+EEL+ + L++EK
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  805  VKQHLEGKTVIKVITVLGKLVNIVVR  830
            V+ ++ GK +IKVI+V  KLVNIV++
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVIK  833

1010) leuS in NC_008800


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  551 bits (2080),  Expect = 7e-158, Method: Compositional matrix adjust.
 Identities = 364/866 (43%), Positives = 551/866 (64%), Gaps = 48/866 (5%)

Query  5    YRPEDIETQVQLHWQEKQTFKVTEDTSKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIS  63
            Y    IE + Q  W +++TFK   D+SK K+Y L M+PYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIEYMKNQLKLLGFGYDWDR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NI   K Q++ LGF+YDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EIATCSPDYYRWEQWFFTKLYEKGMVYKKTSAVNWCPHDLTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W QW+FTKLYEKG+ Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITDYADQLLNDLDTLESWPEQVKTMQRNWIGRSEGVDIVFNVADSEEK  242
            V RK + QW +KIT YA++LL+DL+ ++ WPE +K MQRNWIG+S G ++ F+V D++  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LSVYTTRPDTFMGVTYVAVAAGHPLSLQAAATNPALADFVAECRNTKVAEAEMA----TM  298
            ++V+TTRPDT+ G TY  +A+ H+L    A T +  A+ VA+ +      +++A    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALV--DAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  299  EKKGMATGLYAIHPLTGEKLPIWAANFVLMDYGTGAVMAVPGHDARDWEFATKYNLPIKP  358
            EK G+ TG YAI+P+ G  +P+W A++VL  YGTGA+MAVP+HD RDWEFA ++NL I P
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VILAADGSEPDLSQEAMTEKGILFNSGEFDGLNYEDGFNAVADKLVALGVGQRKVNYRLR  418
            V+        ++ + A TE G+ +NS+ +DGL+   ++  + + L A GVG+ +V YRLR
Sbjct  361  VL-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  419  DWGVSRQRYWGAPIPMVTLEDGTVVPTPEDQLPVILP--EDVVMDGIT-SPIKADPEWAK  475
            DW  SRQRYWG PIP++  EDGT  + PE +LP++LP   D+   G   SP+    +W  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  476  TT-VNGVPGLRETDTFDTFMESSWYYARYTCPQFDKGMLDPAAANYWLPVDQYVGGIEHA  534
             T  +GV G RET+T      SSWYY RY  P+    + D    + WLPVD YVGG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  535  IMHLMYFRFFHKLLRDAGLVDSDEPAKRLLCQGMVLADAFYYSGSNGERIWVSPVDAIVE  594
            ++HL+Y RF HK+L D G+V + EP ++L+ QGM+L+ +  Y +S G    + + D +  
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS--YRDSRGA---LVATDKVEK  590

Query  595  RDDKGRIIKATDAEGHELVYAGMSKMSKSKNNGIDPQVMVEKYGADTVRLFMMFASPAEM  654
            RD  G ++    +E  E    + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P + 
Sbjct  591  RD--GSFFHVETGEELE---QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  655  TLEWQESGVEGANRFLKRVWRLAYDHTAKGATAPLDVANLTEEQKSLRRDLHKTIAKVTD  714
            ++ W E G+EG+ +FL RV RL    T+K  T         E+  +L +  + T+  VT+
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLI---TTKEITE--------ENSGALDKVYNETVKAVTE  694

Query  715  DVGRRQTFNTAIAAVMELMNKLGRAPQETEQDRALLQEALLAVVRMLYPFTPHVCFSLWQ  774
            +V++ + FNTAIA +M ++N        ++++  L+ +   + V+++ PF+PH+   LWQ
Sbjct  695  QVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  775  ALGGEGD-IDTAPWPVADEQAMVEDSKLVVVQVNGKVRGRITVPADATEQQVRERAGQEH  833
            AL + G+ I   PWP  DE  +VE+   +VVQ++GKV++++ V+ D + ++++E A  ++
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  834  LVAKYLDGVTVRKVIYVPGKLLNLVV  859
             V   + G  + KVI VP KL+N+V+
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVI  832

1011) Fbal_0825 in NC_014541


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  551 bits (2080),  Expect = 7e-158, Method: Compositional matrix adjust.
 Identities = 359/865 (42%), Positives = 558/865 (65%), Gaps = 45/865 (5%)

Query  5    YNPAQIESQVQKHWDDNQTFVAKEDPSKEKFYCLSMFPYPSGR-LHMGHVRNYTIGDVIS  63
            Y+ + IE++ Q  W DN+TF +  D+SK KFY L MFPYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RFQRLQGKNVLQPIGWDAFGLPAENAAIKNKSAPGPWTYENIEYMKGQLKMLGFGYDWSR  123
            RF+R QG NVL+P+GWDAFGLPAE+ A+   + P+  T ENI   K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCKPDYYRWEQWFFTELYNKGLIYKKTSAVNWCENDQTVLANEQVV-DGCCWRCDTP  182
            E+ T  P+YY+W QW+FT LY+KGL Y    +VNW E+  T +ANE+V+ DG   R + P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VVQKEIPQWFIKITDYADQLLSDMDQLEGWPEMVKTMQRNWIGRSEGIEMTFDVDGMDES  242
            VV+K + QW +KIT YA++LL D+++++ WPE +K MQRNWIG+S G ++TF V + D  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  FAIYTTRPDTVMGVTYVGIAAGHPLAE--KAAESNPELAAFINECK-NTKVAEAELATME  299
            F+++TTRPDT+ G TY  +A+ H+L +   +++    +A +  +   ++ +A ++LA  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGVATGLYAVHPLSGRKVPIWVANFVLMNYGTGAVMAVPAHDQRDYEFATKYGLDIEGV  359
            K GV TG YA++P++G+ +P+W+A++VL +YGTGA+MAVPAHD+RD EFA ++ LDI  V
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  360  IKPQDGELDISEQAYTDKGILFNSGEFDGLDFDGALNAIAEKLGELGKGHKTTNFRLRDW  419
            +       ++ E A+T+ G+ +NS+ +DGLD  +A+  + E L   G G+    +RLRDW
Sbjct  362  LEGG----NVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDW  417

Query  420  GVSRQRYWGAPIPMATLENGETVTIPAEDLPVVLP--EDVVMDGVT-SPIKADKSWAQTT  476
              SRQRYWG PIP+   E+G + ++P  +LP+VLP   D+   G   SP+     W + T
Sbjct  418  LFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT  477

Query  477  -VNGQPATRETDTFDTFMESSWYYARYTSVGTDDQMLDPAKANYWLPVDQYIGGIEHANM  535
              +G  + RET+T      SSWYY RY      +++ D    + WLPVD Y+GG EHA +
Sbjct  478  REDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVL  537

Query  536  HLLYFRFFHKLLRDAGLVNSDEPAKRLLCQGMVLCDAFYYTGENGQRVWVAPTDVTLERD  595
            HLLY RF HK+L D G+V + EP ++L+ QGM+L  +  Y +  G    + +TD    RD
Sbjct  538  HLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS--YRDSRGA---LVATDKVEKRD  592

Query  596  GKGNIIKATDADGRELVHAGMTKMSKSKNNGIDPQEMVEKYGADTVRLFMMFAAPPELTL  655
            G    + +    G EL +A  +KMSKS +N ++P+++VE+YGADT+R++ MF +P + ++
Sbjct  593  GSFFHVET----GEELEQAP-AKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASI  647

Query  656  EWQESGVEGALRFLKRLWKLSHEHVAKGPAPKLDIASLNNDQKALRRALHQTIAKITDDY  715
             W E G+EG+ +FL R+ +L             +I+  +++  AL +  ++T+  +T++ 
Sbjct  648  AWSEEGLEGSRKFLDRVYRLITTK---------EIT--EENSGALDKVYNETVKAVTEQV  696

Query  716  GRRQTFNTAIAAVMELMNKLTKAPQESDNDRALMQEALDAVVLLLYPITPHTSHALYLAL  775
            ++ + FNTAIA +M ++N        ++++  L  +   + V L+ P++PH ++ L  AL
Sbjct  697  DQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQAL  748

Query  776  GHSGN-VDEAQWPVADQDAMVEDEKLVVVQVNGKVRARITVAADATQEQVQAIGLAEQNV  834
              SG+ +    WP  D+  +VE++  +VVQ++GKV+A++ VA D ++E++Q ++LA+++V
Sbjct  749  TASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKV  808

Query  835  ANFTDGKTIRKVIYVPGKLLNIVAN  859
                 GK I KVI VP KL+NIV +
Sbjct  809  QAEIAGKDIIKVIAVPNKLVNIVIK  833

1012) leuS in NC_005823


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  551 bits (2079),  Expect = 8e-158, Method: Compositional matrix adjust.
 Identities = 353/703 (51%), Positives = 481/703 (69%), Gaps = 57/703 (8%)

Query  199  LVYQAEIPVNWCEALGTVLANEEV---EEWVGKGYEVVRKPMRQYMMRITAYADRLLEDL  255
            L Y+AE+PVNW E LGT +ANEEV         GY VVRKPMRQ M++ITAYA+RLLEDL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  256  ELVEWPPSTLEMQKNWIGKSEGLEITFPFLKPLQSGLEGIRIFTTRPDTIFGVTYMVVAP  315
            E V+WP S  +MQ+NWIGKS G ++TF     ++    ++ +FTTRPDT+FG TY V+AP
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFK----VKDTDKDFTVFTTRPDTLFGATYAVLAP  263

Query  316  EHPIVSEITTPEQKQKVEEYQKTSSLKSDLDRMELNKEKTGVFTGTFVFNPADPSQKIPV  375
            EH++V  ITT++Q + V +Y++ +SLKSDL R +L KEKTGV TG++ +NP +  + +PV
Sbjct  264  EHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAINPVNGKE-MPV  322

Query  376  WISDYVLYGYGTGAIMAVPAHDQRDFEFARTFGLKIIPVIEG-EISEAAFDsktstcins  434
            WI+DYVL +YGTGAIMAVPAHD+RD EFA+ F L IIPV+EG ++ EAAF        + 
Sbjct  323  WIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEAAFTEDGLHINSD  382

Query  435  ssseisinGLDYTSASSKIISWAESKKIGRKKIQFKLRDWLFARQRYWGEPIPLVHYPSG  494
                    GLD +SA +K++ W E+  +G  ++ ++LRDWLF+RQRYWGEPIP++H   G
Sbjct  383  FLD-----GLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDG  437

Query  495  VTKPIPESELPLVLPNLEEFKPSGTGESPLALAKDWLQYKDPSTGEIGTRETNTMPQWAG  554
             + ++PESELPLVLP   +++PSGTGESPLA   DWL+      G  G RETNTMPQWAG
Sbjct  438  TSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT-REDGVKGRRETNTMPQWAG  496

Query  555  SCWYYLRYIDPKNGRFLCDPELEKKWMPVNLYVGGSEHAVLHLLYSRFWHKFLFDIGAVS  614
            S WYYLRYIDP N   L D EL K+W+PV++YVGG+EHAVLHLLY+RFWHK L+D+G V+
Sbjct  497  SSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVP  556

Query  615  TKEPFDKLIHQGLILGE---------------DKR------------------KMSKSLG  641
            TKEPF+KL++QG+ILG                +KR                  KMSKSL 
Sbjct  557  TKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLK  616

Query  642  NVVNPDDVIKEYGADSLRLFEMFMGPLEMVKPWSTRGVEGVFRFLNRIWRLFHSGSQESF  701
            NVVNPDDV+ +YGAD+LR++EMFMGPL+   +WS  G+EG  +FL+R+ RL+ +      
Sbjct  617  NVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTK-----  671

Query  702  RLDDVEPTPEEL-KILHKTIQKVNEDIPNFSFNTAIAQLMIFVNEFTPSDRRPKKVLESF  760
              +  E  +  L K+ + T++ V E++ +  FNTAIAQLM+FVN     D+       +F
Sbjct  672  --EITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGF  729

Query  761  ILLLAPFAPHIAEELWKR-SGKMESLSYEKFPEADPQYLVESEILIVVQVNGKLRDEFKA  819
            + L+APFAPH++EELW+  ++  ES+SY   P  D   LVE+++ IVVQ++GK++  +  
Sbjct  730  VQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVV  789

Query  820  PKDVSQSDAISMAKNLDKIKGILEGKTIRKEIYVPGKLVNLVI  862
            +KD+S+ +   +A   +K+++ + GK I K I VP KLVN+VI
Sbjct  790  AKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832


 Score =  186 bits (691),  Expect = 5e-48, Method: Compositional matrix adjust.
 Identities = 97/142 (69%), Positives = 119/142 (84%), Gaps = 0/142 (0%)

Query  3    YPFQEVESFWQKFWEEHKSFQTNIRSSKPKFYCLDMFPYPSGAGLHVGHPEGYTATDILS  62
            Y    +E+ WQ FW ++ +F+T   +SKPKFY LDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RFKRMKGFEVLHPMGWDAFGLPAERYAMQTGIHPAITTKDNIDNFRRQIQMIGLSYDWSR  122
            RFKR +G +VLHPMGWDAFGLPAE+YAM+TG +PA  T +NI NF+RQI+ +G+SYDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  ELSTTDPDYYKFTQWIFIQLYQ  144
            E++TTDP+YYK TQWIF +LY+
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYE  145

1013) leuS in NC_004369


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  551 bits (2080),  Expect = 8e-158, Method: Compositional matrix adjust.
 Identities = 357/740 (49%), Positives = 501/740 (68%), Gaps = 60/740 (8%)

Query  224  LVYRSNSTVNWCPGLGTVLANEEVTADGRSERGNFPVFRKNLSQWMMRITAYSDRLIDDL  283
            L Y ++  VNW   LGT +ANEEV +DG SERG +PV RK + QWM++ITAY++RL++DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  284  ELLDWPEKVKSMQRNWIGRSRGAEVDFTAE--GETITVFTTRPDTLFGATYMVLAPEHEL  341
            E +DWPE +K MQRNWIG+S GA+V F     +  +TVFTTRPDTLFGATY VLAPEH L
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  342  VDVLVSRGTGSYDGVDPRWTNGQATPAEAVAAYRASIAAKSDLERQE-NKDKTGVFLGVH  400
            VD + +                 +  AEAVA Y+   + KSDL R +  K+KTGV  G  
Sbjct  268  VDAITT-----------------SDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSY  310

Query  401  ATNPVNGEQIPVFIADYVLTGYGTGAIMAVPAHDDRDYEFATVFGLPIVEVVAGGNIAEA  460
            A NPVNG ++PV IADYVL++YGTGAIMAVPAHD+RD EFA  F L I+ V+ GGN+ EA
Sbjct  311  AINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEA  370

Query  461  AYTASGESINSANDQGLDINGLAMVDAVARTIEWLEEKQLGRGTIQYKLRDWLFARQRYW  520
            A+T  G  INS       ++GL    A+A+ +EWLE   +G   + Y+LRDWLF+RQRYW
Sbjct  371  AFTEDGLHINSDF-----LDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYW  425

Query  521  GEPFPVVYDEDGVAYALPESMLPVELPEVEDYKPVSFdpedadsepsppLAKAREWVEVE  580
            GEP+P++  EDG + A+PES LP+ LP   D +P +           +PLA+  +W+EV 
Sbjct  426  GEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSG--------TGESPLANVTDWLEVT  477

Query  581  LDLGDGVKKYTRDTNVMPQWAGSSWYQLRYIDPTNDDQFCNLENEAYWTGPRPDVHGPND  640
             +  DGVK   R+TN MPQWAGSSWY LRYIDP N +++ + E    W            
Sbjct  478  RE--DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWL-----------  523

Query  641  PGGVDLYVGGVEHAVLHLLYSRFWHKVLYDLGYVTSKEPYRRLYNQGYIQAFAYTDSRGV  700
               VD+YVGG EHAVLHLLY+RFWHKVLYDLG V +KEP+++L+NQG I + +Y DSRG 
Sbjct  524  --PVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGA  581

Query  701  YVPAEEVEEKDGKFFY--QGEEVTQEYGKMGKSLKNAVAPDDICNNYGADTLRVYEMSMG  758
             V+++ VE +DG FF    GEE+ Q  +KM+KSLKN V PDD+ ++YGADTLRVYEM MG
Sbjct  582  LVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMG  641

Query  759  PLDTSRPWATKDVVGAQRFLQRLWRLIVDENTGEVLTRDEALTDEDNKHLHRTIAGVRDD  818
            PLD+S +W+  ++ G+++FL+R+ RLI   +  E      AL    +K  + T+ +V ++
Sbjct  642  PLDASIAWSEEGLEGSRKFLDRVYRLITTKEITE--ENSGAL----DKVYNETVKAVTEQ  695

Query  819  YANLRVNTVVAKLIEYVNYLTKTYPDTIPTGAVLPLVVMVSPVAPHIAEELWKKL-GHTD  877
              +++ NT +A+L+ +VN   K   D + ++    +V +++P APH++EELW+ L +  +
Sbjct  696  VDQMKFNTAIAQLMVFVNAANKE--DKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGE  753

Query  878  TVTYEPFPTFEEKWLTDDEVELPVQINGKVRSRITVAADASQEQIIEVALADEKIALQIE  937
            +++Y P P+++E  L +++VE+ VQI+GKV++++ VA D S+E++ EVALA+EK+  +I 
Sbjct  754  SISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIA  813

Query  938  GKNLIKQIVIPGRMVNLVVK  957
            GK++IK I +P ++VN+V+K
Sbjct  814  GKDIIKVIAVPNKLVNIVIK  833


 Score =  140 bits (515),  Expect = 4e-34, Method: Compositional matrix adjust.
 Identities = 78/151 (52%), Positives = 106/151 (71%), Gaps = 11/151 (7%)

Query  25   NAIEREWQNYWTDKGTFNAPNPVGDLAPEDGRELPGDKLFVQDMFPYPSGAGLHVGHPLG  84
             AIE  WQ +W+D+ TF++           G + +  K++  DMFPYPSGAGLHVGHP G
Sbjct  7    TAIEPKWQAFWADNHTFKT-----------GTDASKPKFYALDMFPYPSGAGLHVGHPEG  55

Query  85   YIATDVFARYNRMLGKNVLHTLGYDAFGLPAEQYAIQTGTHPRTTTMANIENMKRQLGAL  144
            Y ATD+++R++R  G NVLH +G DAFGLPAEQYA++TG +P   T  NI N KRQ+ AL
Sbjct  56   YTATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINAL  115

Query  145  GLGHDPRRAVASTDPEFYKWTQWIFLQIFNS  175
            G++ D  R V +TDP++YKWTQWIF ++++ 
Sbjct  116  GFSYDWDREVNTTDPNYYKWTQWIFTKLYEK  146

1014) leuS in NC_003450


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  551 bits (2080),  Expect = 8e-158, Method: Compositional matrix adjust.
 Identities = 357/739 (49%), Positives = 504/739 (69%), Gaps = 59/739 (7%)

Query  220  LVYRSNSTVNWCPGLGTVLANEEVTADGRSERGNFPVFRKNLSQWMMRITAYSDRLIDDL  279
            L Y ++  VNW   LGT +ANEEV +DG SERG +PV RK + QWM++ITAY++RL++DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  280  ELLDWTEKVKSMQRNWIGRSRGAEVDFSAE--GETVTVFTTRPDTLFGATYMVLAPEHEL  337
            E +DW E +K MQRNWIG+S GA+V F     +   TVFTTRPDTLFGATY VLAPEH L
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  338  VDVLLEKAGSYEGVDARWTNGQASPAEAVAAYRASIAAKSDLERQE-NKEKTGVFLGVYA  396
            VD +                  +  AEAVA Y+   + KSDL R +  KEKTGV  G YA
Sbjct  268  VDAI----------------TTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYA  311

Query  397  TNPVNGDQITVFIADYVLTGYGTGAIMAVPAHDERDYEFATVLGLPIKEVVAGGNIEEAA  456
             NPVNG ++ V IADYVL++YGTGAIMAVPAHDERD EFA  + L I  V+ GGN+EEAA
Sbjct  312  INPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEAA  371

Query  457  FTESGEAVNSANDNGLDINGLAKDEAIAKTIEWLEEKELGRGTIQYKLRDWLFARQRYWG  516
            FTE G  +NS       ++GL K  AIAK +EWLE   +G   + Y+LRDWLF+RQRYWG
Sbjct  372  FTEDGLHINSDF-----LDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWG  426

Query  517  EPFPIVYDENGQAHALPDSMLPVELPEVEDYKPVSFdpedadsepsppLAKAREWVEVEL  576
            EP+PI+  E+G + A+P+S LP+ LP   D +P +           +PLA+  +W+EV  
Sbjct  427  EPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSG--------TGESPLANVTDWLEVTR  478

Query  577  DLGDGKKKYTRDTNVMPQWAGSSWYQLRYVDPSNDEQFCNIENERYWTGPRPETHGPNDP  636
            +  DG K   R+TN MPQWAGSSWY LRY+DP N E++ + E  + W             
Sbjct  479  E--DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWL------------  523

Query  637  GGVDLYVGGVEHAVLHLLYARFWHKVLFDLGHVSSKEPYRRLYNQGYIQAFAYTDSRGVY  696
              VD+YVGG EHAVLHLLYARFWHKVL+DLG V++KEP+++L+NQG I + +Y DSRG  
Sbjct  524  -PVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGAL  582

Query  697  VPADDVEEKDGKFFY--QGEEVNQEYGKMGKSLKNAVAPDDICNNFGADTLRVYEMAMGP  754
            V++D VE +DG FF    GEE++Q  +KM+KSLKN V PDD+ +++GADTLRVYEM MGP
Sbjct  583  VATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGP  642

Query  755  LDTSRPWATKDVVGAQRFLQRLWRLVVDENTGEVLTRDEVLTDDDNKQLHRTIAGVRDDY  814
            LD+S +W+  ++ G+++FL+R+ RL+   +  E       L    +K  + T+ +V ++ 
Sbjct  643  LDASIAWSEEGLEGSRKFLDRVYRLITTKEITE--ENSGAL----DKVYNETVKAVTEQV  696

Query  815  TNLRVNTVVAKLIEYVNYLTKTYPDTIPAGAVLPLIVMVSPIAPHIAEELWKKL-GHDDT  873
             +++ NT +A+L+ +VN   K   D + ++    ++ +++P+APH++EELW+ L + +++
Sbjct  697  DQMKFNTAIAQLMVFVNAANKE--DKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGES  754

Query  874  VTYEPFPTFEEKWLTDDEIELPVQVNGKVRGRITVAADASQEQVIEAALADEKVQEQISG  933
            ++Y P P+++E  L ++++E+ VQ++GKV++++ VA D S+E++ E ALA+EKVQ +I+G
Sbjct  755  ISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAG  814

Query  934  KNLIKQIVVPGRMVNLVVK  952
            K++IK I VP ++VN+V+K
Sbjct  815  KDIIKVIAVPNKLVNIVIK  833


 Score =  141 bits (519),  Expect = 2e-34, Method: Compositional matrix adjust.
 Identities = 79/149 (54%), Positives = 104/149 (70%), Gaps = 11/149 (7%)

Query  23   IEGEWQNYWTDNGTFNAPNPVGDLAPADGKALPEDKLFVQDMFPYPSGAGLHVGHPLGYI  82
            IE  WQ +W+DN TF++           G   +  K++  DMFPYPSGAGLHVGHP GY 
Sbjct  9    IEPKWQAFWADNHTFKT-----------GTDASKPKFYALDMFPYPSGAGLHVGHPEGYT  57

Query  83   ATDVFARYNRMLGKNVLHTLGYDAFGLPAEQYAIQTGTHPRTTTMANIENMKRQLGALGL  142
            ATD+++R++R  G NVLH +G DAFGLPAEQYA++TG +P   T  NI N KRQ+ ALG+
Sbjct  58   ATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGF  117

Query  143  GHDSRRAVATTDPEFYKWTQWIFLQIFNS  171
            + D  R V TTDP++YKWTQWIF ++++ 
Sbjct  118  SYDWDREVNTTDPNYYKWTQWIFTKLYEK  146

1015) leuS in NC_022040


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  551 bits (2080),  Expect = 8e-158, Method: Compositional matrix adjust.
 Identities = 357/739 (49%), Positives = 504/739 (69%), Gaps = 59/739 (7%)

Query  220  LVYRSNSTVNWCPGLGTVLANEEVTADGRSERGNFPVFRKNLSQWMMRITAYSDRLIDDL  279
            L Y ++  VNW   LGT +ANEEV +DG SERG +PV RK + QWM++ITAY++RL++DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  280  ELLDWTEKVKSMQRNWIGRSRGAEVDFSAE--GETVTVFTTRPDTLFGATYMVLAPEHEL  337
            E +DW E +K MQRNWIG+S GA+V F     +   TVFTTRPDTLFGATY VLAPEH L
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  338  VDVLLEKAGSYEGVDARWTNGQASPAEAVAAYRASIAAKSDLERQE-NKEKTGVFLGVYA  396
            VD +                  +  AEAVA Y+   + KSDL R +  KEKTGV  G YA
Sbjct  268  VDAI----------------TTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYA  311

Query  397  TNPVNGDQITVFIADYVLTGYGTGAIMAVPAHDERDYEFATVLGLPIKEVVAGGNIEEAA  456
             NPVNG ++ V IADYVL++YGTGAIMAVPAHDERD EFA  + L I  V+ GGN+EEAA
Sbjct  312  INPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEAA  371

Query  457  FTESGEAVNSANDNGLDINGLAKDEAIAKTIEWLEEKELGRGTIQYKLRDWLFARQRYWG  516
            FTE G  +NS       ++GL K  AIAK +EWLE   +G   + Y+LRDWLF+RQRYWG
Sbjct  372  FTEDGLHINSDF-----LDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWG  426

Query  517  EPFPIVYDENGQAHALPDSMLPVELPEVEDYKPVSFdpedadsepsppLAKAREWVEVEL  576
            EP+PI+  E+G + A+P+S LP+ LP   D +P +           +PLA+  +W+EV  
Sbjct  427  EPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSG--------TGESPLANVTDWLEVTR  478

Query  577  DLGDGKKKYTRDTNVMPQWAGSSWYQLRYVDPSNDEQFCNIENERYWTGPRPETHGPNDP  636
            +  DG K   R+TN MPQWAGSSWY LRY+DP N E++ + E  + W             
Sbjct  479  E--DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWL------------  523

Query  637  GGVDLYVGGVEHAVLHLLYARFWHKVLFDLGHVSSKEPYRRLYNQGYIQAFAYTDSRGVY  696
              VD+YVGG EHAVLHLLYARFWHKVL+DLG V++KEP+++L+NQG I + +Y DSRG  
Sbjct  524  -PVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGAL  582

Query  697  VPADDVEEKDGKFFY--QGEEVNQEYGKMGKSLKNAVAPDDICNNFGADTLRVYEMAMGP  754
            V++D VE +DG FF    GEE++Q  +KM+KSLKN V PDD+ +++GADTLRVYEM MGP
Sbjct  583  VATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGP  642

Query  755  LDTSRPWATKDVVGAQRFLQRLWRLVVDENTGEVLTRDEVLTDDDNKQLHRTIAGVRDDY  814
            LD+S +W+  ++ G+++FL+R+ RL+   +  E       L    +K  + T+ +V ++ 
Sbjct  643  LDASIAWSEEGLEGSRKFLDRVYRLITTKEITE--ENSGAL----DKVYNETVKAVTEQV  696

Query  815  TNLRVNTVVAKLIEYVNYLTKTYPDTIPAGAVLPLIVMVSPIAPHIAEELWKKL-GHDDT  873
             +++ NT +A+L+ +VN   K   D + ++    ++ +++P+APH++EELW+ L + +++
Sbjct  697  DQMKFNTAIAQLMVFVNAANKE--DKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGES  754

Query  874  VTYEPFPTFEEKWLTDDEIELPVQVNGKVRGRITVAADASQEQVIEAALADEKVQEQISG  933
            ++Y P P+++E  L ++++E+ VQ++GKV++++ VA D S+E++ E ALA+EKVQ +I+G
Sbjct  755  ISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAG  814

Query  934  KNLIKQIVVPGRMVNLVVK  952
            K++IK I VP ++VN+V+K
Sbjct  815  KDIIKVIAVPNKLVNIVIK  833


 Score =  141 bits (519),  Expect = 2e-34, Method: Compositional matrix adjust.
 Identities = 79/149 (54%), Positives = 104/149 (70%), Gaps = 11/149 (7%)

Query  23   IEGEWQNYWTDNGTFNAPNPVGDLAPADGKALPEDKLFVQDMFPYPSGAGLHVGHPLGYI  82
            IE  WQ +W+DN TF++           G   +  K++  DMFPYPSGAGLHVGHP GY 
Sbjct  9    IEPKWQAFWADNHTFKT-----------GTDASKPKFYALDMFPYPSGAGLHVGHPEGYT  57

Query  83   ATDVFARYNRMLGKNVLHTLGYDAFGLPAEQYAIQTGTHPRTTTMANIENMKRQLGALGL  142
            ATD+++R++R  G NVLH +G DAFGLPAEQYA++TG +P   T  NI N KRQ+ ALG+
Sbjct  58   ATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGF  117

Query  143  GHDSRRAVATTDPEFYKWTQWIFLQIFNS  171
            + D  R V TTDP++YKWTQWIF ++++ 
Sbjct  118  SYDWDREVNTTDPNYYKWTQWIFTKLYEK  146

1016) B601_0659 in NC_018622


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  551 bits (2078),  Expect = 8e-158, Method: Compositional matrix adjust.
 Identities = 335/724 (47%), Positives = 506/724 (70%), Gaps = 23/724 (3%)

Query  1    MGFSYDEGREFATSDPDYYRWTQKLFLFLYEKGLAYMADMAVNYCEELGTVLANEEV-EN  59
            +GFSYD +RE  T+DP+YY+WTQ +F  LYEKGLAY A+++VN  EELGT +ANEEV  +
Sbjct  115  LGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPD  174

Query  60   GLSVEGGYPVERRMLRQWILRITAYSDQLLQGLEDLDWPENVKQLQRNWIGKSEGALVRF  119
            G S  GGYPV R+ +RQW+L+ITAY+++LL++LE++DWPE++K++QRNWIGKS GA V F
Sbjct  175  GTSERGGYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTF  234

Query  120  EV-DNGNFLSVFTTRPDTLCGVSFLVMAPEHPEINHLVSEEQHSAVENYIRCVQSKSERE  178
             V D ++ ++VFTTRPDTL G ++ V+APEH+ ++ + + +Q  AV +Y R    KS+  
Sbjct  235  KVKDTDKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLA  294

Query  179  RISETKVKSGVFIGAYAKHPITGAPLPIWVSDYVIMGYGSGVVMGVPAHDERDREFANAF  238
            R   +K K+GV  G+YA +P+ G  +P+W++DYV+ +YG+G +M+VPAHDERD+EFA+ F
Sbjct  295  RTDLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQF  354

Query  239  ALPISEVLDDNG--QCIHSNHG-----DFLLNGLRGKEASDYVIAYLQKKNLGEGKVVYK  291
             L I  VL++    +   +++G     DFL +GL    A   ++  L+   +G+ +V Y+
Sbjct  355  NLDIIPVLEGGNVEEAAFTEDGLHINSDFL-DGLDKASAIAKMVEWLEAEGVGNENVTYR  413

Query  292  LRDWLFSRQRYWGEPIPIIHFEDGTCRpleddelpllppeIQDYRPKGFGQGPLANVKEW  351
            LRDWLFSRQRYWGEPIPIIH EDGT  ++ + ELPL+ P  +D RP G G++PLANV +W
Sbjct  414  LRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDW  473

Query  352  VEIHDVKTNRKGRRETHTMPQWAGSCWYYLRFCDAHNSQAPWSNENERYWMPVDLYIGGA  411
            +E+       KGRRET+TMPQWAGS WYYLR+ D+HN++    +E  + W+PVD+Y+GGA
Sbjct  474  LEVTR-EDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGA  532

Query  412  EHAVLHLLYSRFWHRVFYEAGLVSTPEPFKKLINQGLVLATSYRIPGKGYVHPEDVREDN  471
            EHAVLHLLY+RFWH+V+Y+ G+V+T EPF+KL+NQG++L+TSYR +  + V  + V   +
Sbjct  533  EHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRD  592

Query  472  GK-WTTASGEELEVRQEKMSKSKLNGVDPQTLIDEFGADALRMYAMFSGPLDKNKLWCNH  530
            G      +GEELE    KMSKS  N V+P+ +++++GAD+LR+Y MF GPLD +  W ++
Sbjct  593  GSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEE  652

Query  531  GVSGCRRFLNRFYELVTSSAVQDVDDPKGMALAHKLVHRVGEDIEKMSLNTIPSSFMEFI  590
            G+ G R+FL+R Y L+T+  + + +      + +  V  V E++++M +NT  + +M F+
Sbjct  653  GLEGSRKFLDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFV  712

Query  591  NEFTK----LDTYPKSALAMVVRALAPIAPHISEELWTIL-GYAPGIDKAEWPEVDPKYL  645
            N   K    +  Y+K+ + ++    AP+APH++EELW  L + + +I    WP  D   L
Sbjct  713  NAANKEDKLFSDYAKGFVQLI----APFAPHLGEELWQALTASGESISYVPWPSYDESKL  768

Query  646  EDASVTFVIQVNGKLRARLDIDKNTSQEDI--LSAARESVAKYLEDKEIKKEVFVPNRLV  703
             +  V +V+Q++GK++A+L + K+ S+E++  ++ A E V   + +K+I K + VPN+LV
Sbjct  769  VENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLV  828

Query  704  NFVL  707
            N+V+
Sbjct  829  NIVI  832

1017) leuS in NC_021591


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  551 bits (2080),  Expect = 8e-158, Method: Compositional matrix adjust.
 Identities = 367/866 (43%), Positives = 556/866 (65%), Gaps = 48/866 (5%)

Query  41   YRPEDIESNVQLHWQEKQTFKVTEDASKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIS  99
            Y    IE++ Q  W +++TFK   DASK K+Y L M+PYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  100  RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIEYMKNQLKLLGFGYDWDR  159
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NI   K Q++ LGF+YDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  160  EIATCDPDYYRWEQWFFTKLYEKGLVYKKTSAVNWCPHDLTVLANEQVI-DGCCWRCDTK  218
            E+ T DP+YY+W QW+FTKLYEKGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  219  VERKEIPQWFIKITDYADQLLNDLDTLESWPEQVKTMQRNWIGRSEGVDITFEVAGSDEK  278
            V RK + QW +KIT YA++LL+DL+ ++ WPE +K MQRNWIG+S G ++TF V ++D  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  279  LTVYTTRPDTFMGATYVAVAAGHPLAQQGAVNNPALAEFIEECRNTKVAEADMA----TM  334
            +TV+TTRPDT+ GATY  +A+ H+L +  A+  +  AE + + +      +D+A    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVD--AITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  335  EKKGMPTGLFAIHPLSGEKVPVWVANFVLMEYGTGAVMAVPAHDQRDWEFATKYGLPIKP  394
            EK G+ TG +AI+P++G  +PVW+A++VL  YGTGA+MAVPAHD+RDWEFA ++ L I P
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  395  VVLTLDGSQPDVHAEAMTEKGTLFNSGEFDGLDHEAGFNAIADKLVAMGVGQRKVNYRLR  454
            V   L+G+  +V+  A TE G  +NS+ +DGLD  +++  + + L A GVG+ +V YRLR
Sbjct  361  V---LEGG--NVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  455  DWGVSRQRYWGAPIPMVTLEDGTVMPTPEDQLPVILP--EDVVMDGIT-SPIKADPEWAK  511
            DW  SRQRYWG PIP++  EDGT  + PE +LP++LP   D+   G   SP+    +W  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  512  TT-VNGQPALRETDTFDTFMESSWYYARYTCPQYDQGMLDPAAANYWLPVDQYVGGIEHA  570
             T  +G  + RET+T      SSWYY RY  P+  + + D    + WLPVD YVGG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  571  IMHLMYFRFFHKLLRDAGLVDSDEPAKRLLCQGMVLADAFYYTGNSGERVWVSPVDATVE  630
            ++HL+Y RF HK+L D G+V + EP ++L+ QGM+L+ +  Y ++ G  V        VE
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS--YRDSRGALV----ATDKVE  589

Query  631  RDDKGRIVKATDPQGRELVYAGMSKMSKSKNNGIDPQVMVEKYGADTVRLFMMFASPAEM  690
            + D G +      +  E    + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P + 
Sbjct  590  KRD-GSFFHVETGEELE---QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  691  TLEWQESGVEGANRFLKRVWKLAYEHLEKGAVQPLNVAALNEDQKALRRDLHKTIAKVTD  750
            ++ W E G+EG+ +FL RV +L         +   +++  +E+  AL +  + T+  VT+
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRL---------ITTKEIT--EENSGALDKVYNETVKAVTE  694

Query  751  DIGRRQTFNTAIAAVMELMNKLARAPQDSEQDRALLQEALLSVVRMLYPFTPHVCFSLWQ  810
            ++++ + FNTAIA +M ++N        ++++  L+ +   + V+++ PF+PH+   LWQ
Sbjct  695  QVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  811  ALGGEGD-VDTAAWPQADEQAMVEDSKLVVVQVNGKVRAKITVAADATEEQVRARAAEEH  869
            AL + G+ +   +WP  DE  +VE+   +VVQ++GKV+AK+ VA D + E+++  A  ++
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  870  LVAKYLDGVTVRKVIYVPGKLLNLVV  895
             V   + G  + KVI VP KL+N+V+
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVI  832

1018) leuS in NC_008609


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  551 bits (2079),  Expect = 8e-158, Method: Compositional matrix adjust.
 Identities = 359/857 (42%), Positives = 538/857 (63%), Gaps = 67/857 (7%)

Query  5    YNPAAVEQKWQQQWETGASFAVNEQSDRPKYYLLEMFPYPSGR-IHMGHVRNYSIGDVIG  63
            Y+ +A+E KWQ  W    +F    ++ +PK+Y L+MFPYPSG  +H+GH   Y+  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RFKRMRGFNVLHPMGWDAFGMPAENAAIQNKSHPAKWTYENIDYMRGQLKKMGLSYDWGR  123
            RFKR +G NVLHPMGWDAFG+PAE+ A++  ++PA  T ENI   + Q++ +G+SYDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCDLEYYRWEQKIFLEMFAKGLAYKKTSYVNWCPTCETVLANEQV-EDGACWRCDSP  182
            E+ T D +YY+W Q IF  ++ KGLAY     VNW     T +ANE+V  DG+  R + P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VQQKELDQWFFRITQYAEELLSYTEKLPGWPERVLVMQKNWIGKSHGCEVDFPLEGGTGS  242
            V +K + QW ++IT YAE LL   E + +WPE +  MQ+NWIGKS G +V F + +    
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  VRVFTTRPDTLFGATFMSLAPEHPQARELTTPDRRDEVERFIEKVRNTDRSKRTADDYEK  302
              VFTTRPDTLFGAT+  LAPEH+    +TT+D+ + V  +  +        RT    EK
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEK  302

Query  303  EGVFTGSYCINPLTQVRMPIYLANFVLTDYGTGAVMAVPTHDQRDFEFAKKYGLDLKVVI  362
             GV TGSY INP+    MP+ +A++VL+ YGTGA+MAVP+HD+RD EFAK++ LD+  V+
Sbjct  303  TGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL  362

Query  363  QPEGTTLDPATMEAAYTEPGIMVNSGTFDGMGSEEAKQAIADHLQEMGGGTKTVTYRLRD  422
              EG  ++    EAA+TE G+ +NS+ +DG++   A   + + L+  G G   VTYRLRD
Sbjct  363  --EGGNVE----EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  423  WGISRQRYWGNPIPVIYCDCCGVVPVPEKDLPVRLPMDVEF--TGEGGSPLARLESFINV  480
            W +SRQRYWG+PIP+I  +     +VPE +LP+ LP+  ++  +G G SPLA +   ++V
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  481  PCPTCGKPARRETDTMDTFVQSSWYFLRYCCPDFHDAPLDRTRVDYWMSVDQYIGGIEHA  540
                  K +RRET+TM     SSWY+LRY  P+  +   D   +  W++VD Y+GG EHA
Sbjct  477  TREDGVK-GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  541  VLHLLYARFFTKVLRDLGYVECSEPFTNLLTQGMVI-------------------KDG--  579
            VLHLLYARF  KVL DLG V   EPF +L+ QGM++                   +DG  
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSF  595

Query  580  -------------AKMSKSKGNVVDPNALIERYGADTARLFSLFAAPPEKDLDWNDQGVD  626
                         AKMSKS  NVV+P+ ++E+YGADT R++ +F +P +  + W+++G++
Sbjct  596  FHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLE  655

Query  627  GSFRFLNRVWKLVNDRLELISGAAPLDVPGLTGEERTLRRAVHKTIRKVTEDIEGRFHFN  686
            GS +FL+RV +L+  +      +++LD            +  + T++ VTE+++ +  FN
Sbjct  656  GSRKFLDRVYRLITTKEITEENSGALD------------KVYNETVKAVTEQVD-QMKFN  702

Query  687  TAIAAVMELLNVLQSADLSTPQAGAVMKEALESLVLLLAPFVPHMAEELWQRMGQPG-AL  745
            TAIA +M ++N       ++ + + +  +   ++V L+APF PH++EELWQ +  +G ++
Sbjct  703  TAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESI  755

Query  746  STTPWPEYDREAAVDDEVLMVVQVNGKLRSKITVAAGSDEESLKALALADDKVQPFLQGV  805
            S  PWP YD    V+++V +VVQ++GK+++K+ VA +   E L+ +ALA++KVQ+ + G 
Sbjct  756  SYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGK  815

Query  806  QVRKVICVKGKLVNIVV  822
            ++ KVI V  KLVNIV+
Sbjct  816  DIIKVIAVPNKLVNIVI  832

1019) leuS in NC_021659


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  551 bits (2079),  Expect = 9e-158, Method: Compositional matrix adjust.
 Identities = 367/866 (43%), Positives = 556/866 (65%), Gaps = 48/866 (5%)

Query  5    YRPEDIESNVQLHWQEKQTFKVTEDASKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIS  63
            Y    IE++ Q  W +++TFK   DASK K+Y L M+PYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIEYMKNQLKLLGFGYDWDR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NI   K Q++ LGF+YDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EIATCDPDYYRWEQWFFTKLYEKGLVYKKTSAVNWCPHDLTVLANEQVI-DGCCWRCDTK  182
            E+ T DP+YY+W QW+FTKLYEKGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITDYADQLLNDLDTLESWPEQVKTMQRNWIGRSEGVDITFDVAGSDEK  242
            V RK + QW +KIT YA++LL+DL+ ++ WPE +K MQRNWIG+S G ++TF V ++D  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGATYVAVAAGHPLAQQGAVNNPALAEFIEECRNTKVAEADMA----TM  298
            +TV+TTRPDT+ GATY  +A+ H+L +  A+  +  AE + + +      +D+A    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVD--AITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  299  EKKGMPTGLFAIHPLSGEKVPVWVANFVLMEYGTGAVMAVPAHDQRDWEFATKYGLPIKP  358
            EK G+ TG +AI+P++G  +PVW+A++VL  YGTGA+MAVPAHD+RDWEFA ++ L I P
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VVLTLDGSQPDVHAEAMTEKGTLFNSGEFDGLDHEAGFNAIADKLVAMGVGQRKVNYRLR  418
            V   L+G+  +V+  A TE G  +NS+ +DGLD  +++  + + L A GVG+ +V YRLR
Sbjct  361  V---LEGG--NVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  419  DWGVSRQRYWGAPIPMVTLEDGTVMPTPEDQLPVILP--EDVVMDGIT-SPIKADPEWAK  475
            DW  SRQRYWG PIP++  EDGT  + PE +LP++LP   D+   G   SP+    +W  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  476  TT-VNGQPALRETDTFDTFMESSWYYARYTCPQYDQGMLDPAAANYWLPVDQYVGGIEHA  534
             T  +G  + RET+T      SSWYY RY  P+  + + D    + WLPVD YVGG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  535  IMHLMYFRFFHKLLRDAGLVDSDEPAKRLLCQGMVLADAFYYTGNSGERVWVSPVDATVE  594
            ++HL+Y RF HK+L D G+V + EP ++L+ QGM+L+ +  Y ++ G  V        VE
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS--YRDSRGALV----ATDKVE  589

Query  595  RDDKGRIVKATDPQGRELVYAGMSKMSKSKNNGIDPQVMVEKYGADTVRLFMMFASPAEM  654
            + D G +      +  E    + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P + 
Sbjct  590  KRD-GSFFHVETGEELE---QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  655  TLEWQESGVEGANRFLKRVWKLAYEHLEKGAVQPLNVAALNEDQKALRRDLHKTIAKVTD  714
            ++ W E G+EG+ +FL RV +L         +   +++  +E+  AL +  + T+  VT+
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRL---------ITTKEIT--EENSGALDKVYNETVKAVTE  694

Query  715  DIGRRQTFNTAIAAVMELMNKLARAPQDSEQDRALLQEALLSVVRMLYPFTPHVCFSLWQ  774
            ++++ + FNTAIA +M ++N        ++++  L+ +   + V+++ PF+PH+   LWQ
Sbjct  695  QVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  775  ALGGEGD-VDTAAWPQADEQAMVEDSKLVVVQVNGKVRAKITVAADATEEQVRARAAEEH  833
            AL + G+ +   +WP  DE  +VE+   +VVQ++GKV+AK+ VA D + E+++  A  ++
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  834  LVAKYLDGVTVRKVIYVPGKLLNLVV  859
             V   + G  + KVI VP KL+N+V+
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVI  832

1020) B603_0664 in NC_018624


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  550 bits (2076),  Expect = 1e-157, Method: Compositional matrix adjust.
 Identities = 335/724 (47%), Positives = 506/724 (70%), Gaps = 23/724 (3%)

Query  1    MGFSYDEGREFATSDPDYYRWTQKLFLFLYEKGLAYMADMAVNYCEELGTVLANEEV-EN  59
            +GFSYD +RE  T+DP+YY+WTQ +F  LYEKGLAY A+++VN  EELGT +ANEEV  +
Sbjct  115  LGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPD  174

Query  60   GLSVEGGYPVERRMLRQWILRITAYSDQLLQGLEDLDWPENVKQLQRNWIGKSEGALVRF  119
            G S  GGYPV R+ +RQW+L+ITAY+++LL++LE++DWPE++K++QRNWIGKS GA V F
Sbjct  175  GTSERGGYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTF  234

Query  120  EV-DNGNFLSVFTTRPDTLCGVSFLVMAPEHPEINHLVSEEQRSAVENYIRCVQSKSERE  178
             V D ++ ++VFTTRPDTL G ++ V+APEH+ ++ + + +Q  AV +Y R    KS+  
Sbjct  235  KVKDTDKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLA  294

Query  179  RISETKVKSGVFIGAYAKHPITGAPLPIWVSDYVIMGYGSGVVMGVPAHDERDREFANAF  238
            R   +K K+GV  G+YA +P+ G  +P+W++DYV+ +YG+G +M+VPAHDERD+EFA+ F
Sbjct  295  RTDLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQF  354

Query  239  ALPISEVLDDNG--QCIHSNHG-----DFLLNGLRGKEASDYVIAYLQKKNLGEGKVVYK  291
             L I  VL++    +   +++G     DFL +GL    A   ++  L+   +G+ +V Y+
Sbjct  355  NLDIIPVLEGGNVEEAAFTEDGLHINSDFL-DGLDKASAIAKMVEWLEAEGVGNENVTYR  413

Query  292  LRDWLFSRQRYWGEPIPIIHFEDGTCRpleddelpllppeIQDYRPKGFGQGPLANVKEW  351
            LRDWLFSRQRYWGEPIPIIH EDGT  ++ + ELPL+ P  +D RP G G++PLANV +W
Sbjct  414  LRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDW  473

Query  352  VEIHDVKTNRKGRRETHTMPQWAGSCWYYLRFCDAHNSQAPWSNENERYWMPVDLYIGGA  411
            +E+       KGRRET+TMPQWAGS WYYLR+ D+HN++    +E  + W+PVD+Y+GGA
Sbjct  474  LEVTR-EDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGA  532

Query  412  EHAVLHLLYSRFWHRVFYEAGLVSTPEPFKKLINQGLVLATSYRIPGKGYVHPEDVREDN  471
            EHAVLHLLY+RFWH+V+Y+ G+V+T EPF+KL+NQG++L+TSYR +  + V  + V   +
Sbjct  533  EHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRD  592

Query  472  GK-WTTASGEELEVRQEKMSKSKLNGVDPQTLIDEFGADALRMYAMFSGPLDKNKLWCNH  530
            G      +GEELE    KMSKS  N V+P+ +++++GAD+LR+Y MF GPLD +  W ++
Sbjct  593  GSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEE  652

Query  531  GVSGCRRFLNRFYELVTSSAVQDVDDPKGMALAHKLVHRVGEDIEKMSLNTIPSSFMEFI  590
            G+ G R+FL+R Y L+T+  + + +      + +  V  V E++++M +NT  + +M F+
Sbjct  653  GLEGSRKFLDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFV  712

Query  591  NEFTK----LDTYPKSALAMVVRALAPIAPHISEELWTIL-GYAPGIDKAEWPEVDPKYL  645
            N   K    +  Y+K+ + ++    AP+APH++EELW  L + + +I    WP  D   L
Sbjct  713  NAANKEDKLFSDYAKGFVQLI----APFAPHLGEELWQALTASGESISYVPWPSYDESKL  768

Query  646  EDASVTFVIQVNGKLRARLDIDKNTSQEDI--LSAARESVAKYLEDKEIKKEVFVPNRLV  703
             +  V +V+Q++GK++A+L + K+ S+E++  ++ A E V   + +K+I K + VPN+LV
Sbjct  769  VENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLV  828

Query  704  NFVL  707
            N+V+
Sbjct  829  NIVI  832

1021) YE105_C1241 in NC_015224


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  550 bits (2077),  Expect = 1e-157, Method: Compositional matrix adjust.
 Identities = 364/866 (43%), Positives = 550/866 (64%), Gaps = 48/866 (5%)

Query  5    YRPEDIETQVQLHWQEKQTFKVTEDTSKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIS  63
            Y    IE + Q  W +++TFK   D+SK K+Y L M+PYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIEYMKNQLKLLGFGYDWDR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NI   K Q++ LGF+YDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EITTCSPDYYRWEQWFFTKLYEKGMVYKKTSAVNWCPHDLTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W QW+FTKLYEKG+ Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITDYADQLLNDLDRLESWPEQVKTMQRNWIGRSEGVDIVFNVADSEEK  242
            V RK + QW +KIT YA++LL+DL+ ++ WPE +K MQRNWIG+S G ++ F+V D++  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LSVYTTRPDTFMGVTYVAVAAGHPLSLQAAATNPALADFVAECRNTKVAEAEMA----TM  298
            ++V+TTRPDT+ G TY  +A+ H+L    A T +  A+ VA+ +      +++A    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALV--DAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  299  EKKGMATGLYAIHPLTGEKLPIWAANFVLMDYGTGAVMAVPGHDARDWEFATKYNLPIKP  358
            EK G+ TG YAI+P+ G  +P+W A++VL  YGTGA+MAVP+HD RDWEFA ++NL I P
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VILAADGSEPDLSQEAMTEKGILFNSGEFDGLNYEDGFNAVADKLVALGVGQRKVNYRLR  418
            V+        ++ + A TE G+ +NS+ +DGL+   ++  + + L A GVG+ +V YRLR
Sbjct  361  VL-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  419  DWGVSRQRYWGAPIPMVTLEDGTVVPTPEDQLPVILP--EDVVMDGIT-SPIKADPEWAK  475
            DW  SRQRYWG PIP++  EDGT  + PE +LP++LP   D+   G   SP+    +W  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  476  TT-VSGVPGLRETDTFDTFMESSWYYARYTCPQFDKGMLDPAAANYWLPVDQYVGGIEHA  534
             T   GV G RET+T      SSWYY RY  P+    + D    + WLPVD YVGG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  535  IMHLMYFRFFHKLLRDAGLVDSDEPAKRLLCQGMVLADAFYYSGSNGERIWVSPVDAIVE  594
            ++HL+Y RF HK+L D G+V + EP ++L+ QGM+L+ +  Y +S G    + + D +  
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS--YRDSRGA---LVATDKVEK  590

Query  595  RDDKGRITKATDAEGHELVYAGMSKMSKSKNNGIDPQVMVEKYGADTVRLFMMFASPAEM  654
            RD  G +     +E  E    + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P + 
Sbjct  591  RD--GSFFHVETGEELE---QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  655  TLEWQESGVEGANRFLKRVWRLVYDHTAKGATAPLDIANLTEEQKSLRRDLHKTIAKVTD  714
            ++ W E G+EG+ +FL RV RL+   T+K  T         E+  +L +  + T+  VT+
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLI---TTKEITE--------ENSGALDKVYNETVKAVTE  694

Query  715  DVGRRQTFNTAIAAVMELMNKLGRAPQETEQDRALLQEALLAVVRMLYPFTPHVCFSLWQ  774
            +V++ + FNTAIA +M ++N        ++++  L+ +   + V+++ PF+PH+   LWQ
Sbjct  695  QVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  775  ALGGEGD-IDTAPWPIADEQAMVEDSKLVVVQVNGKVRGRITVPADATEQQVRERAGQEH  833
            AL + G+ I   PWP  DE  +VE+   +VVQ++GKV++++ V+ D + ++++E A  ++
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  834  LVAKYLDGVTVRKVIYVPGKLLNLVV  859
             V   + G  + KVI VP KL+N+V+
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVI  832

1022) Y11_19181 in NC_017564


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  550 bits (2077),  Expect = 1e-157, Method: Compositional matrix adjust.
 Identities = 364/866 (43%), Positives = 550/866 (64%), Gaps = 48/866 (5%)

Query  5    YRPEDIETQVQLHWQEKQTFKVTEDTSKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIS  63
            Y    IE + Q  W +++TFK   D+SK K+Y L M+PYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIEYMKNQLKLLGFGYDWDR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NI   K Q++ LGF+YDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EITTCSPDYYRWEQWFFTKLYEKGMVYKKTSAVNWCPHDLTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W QW+FTKLYEKG+ Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITDYADQLLNDLDRLESWPEQVKTMQRNWIGRSEGVDIVFNVADSEEK  242
            V RK + QW +KIT YA++LL+DL+ ++ WPE +K MQRNWIG+S G ++ F+V D++  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LSVYTTRPDTFMGVTYVAVAAGHPLSLQAAATNPALADFVAECRNTKVAEAEMA----TM  298
            ++V+TTRPDT+ G TY  +A+ H+L    A T +  A+ VA+ +      +++A    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALV--DAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  299  EKKGMATGLYAIHPLTGEKLPIWAANFVLMDYGTGAVMAVPGHDARDWEFATKYNLPIKP  358
            EK G+ TG YAI+P+ G  +P+W A++VL  YGTGA+MAVP+HD RDWEFA ++NL I P
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VILAADGSEPDLSQEAMTEKGILFNSGEFDGLNYEDGFNAVADKLVALGVGQRKVNYRLR  418
            V+        ++ + A TE G+ +NS+ +DGL+   ++  + + L A GVG+ +V YRLR
Sbjct  361  VL-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  419  DWGVSRQRYWGAPIPMVTLEDGTVVPTPEDQLPVILP--EDVVMDGIT-SPIKADPEWAK  475
            DW  SRQRYWG PIP++  EDGT  + PE +LP++LP   D+   G   SP+    +W  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  476  TT-VSGVPGLRETDTFDTFMESSWYYARYTCPQFDKGMLDPAAANYWLPVDQYVGGIEHA  534
             T   GV G RET+T      SSWYY RY  P+    + D    + WLPVD YVGG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  535  IMHLMYFRFFHKLLRDAGLVDSDEPAKRLLCQGMVLADAFYYSGSNGERIWVSPVDAIVE  594
            ++HL+Y RF HK+L D G+V + EP ++L+ QGM+L+ +  Y +S G    + + D +  
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS--YRDSRGA---LVATDKVEK  590

Query  595  RDDKGRIIKATDAEGHELVYAGMSKMSKSKNNGIDPQVMVEKYGADTVRLFMMFASPAEM  654
            RD  G ++    +E  E    + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P + 
Sbjct  591  RD--GSFFHVETGEELE---QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  655  TLEWQESGVEGANRFLKRVWRLAYDHTAKGATAPLDIANLTEEQKSLRRDLHKTIAKVTD  714
            ++ W E G+EG+ +FL RV RL    T+K  T         E+  +L +  + T+  VT+
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLI---TTKEITE--------ENSGALDKVYNETVKAVTE  694

Query  715  DVGRRQTFNTAIAAVMELMNKLGRAPQETEQDRALLQEALLAVVRMLYPFTPHVCFSLWQ  774
            +V++ + FNTAIA +M ++N        ++++  L+ +   + V+++ PF+PH+   LWQ
Sbjct  695  QVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  775  ALGGEGD-IDTAPWPIADEQAMVEDSKLVVVQVNGKVRGRITVPADATEQQVRERAGQEH  833
            AL + G+ I   PWP  DE  +VE+   +VVQ++GKV++++ V+ D + ++++E A  ++
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  834  LVAKYLDGVTVRKVIYVPGKLLNLVV  859
             V   + G  + KVI VP KL+N+V+
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVI  832

1023) leuS in NC_016512


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  550 bits (2077),  Expect = 1e-157, Method: Compositional matrix adjust.
 Identities = 350/853 (42%), Positives = 533/853 (63%), Gaps = 60/853 (7%)

Query  11   YDAVAAQEKWSKYWEEHRTFASLDDGSRERRYVLDMFAYPSG-DLHMGHAEAFAIGDVLA  69
            YD  A + KW  +W +++TF +  D+S+ + Y LDMF+YPSG +LH+GH+E+++  D+L+
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  70   RYWRLRGFDVLHPVGWDSFGLPAENAAIKHGTHPAEWTYRNIDTQAASFKRYAVSFDWSM  129
            R+ R +G +VLHP+GWD+FGLPAE+ A+  G +PAE T  NI      ++  + S+DW  
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  130  RLHTSDEEYYRWTQWLFNRFFEKGLAYRKDSWANWCPNDQTVLANEQV-KDGCCERCGAV  188
             ++T+D +YY+WTQW+F +++EKGLAY  +   NW  +  T +ANE+V  DG  ER G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  189  VTKRQLNQWYFRITDYAQRLLDDMDQIEGKWPERVLSMQRNWIGRSEGAYVDFTIDGRKE  248
            V ++ + QW ++IT YA+RLL+D+++++  WPE +  MQRNWIG+S GA V F + +   
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD--WPESIKDMQRNWIGKSTGANVTFKVKDTDK  241

Query  249  PVRVFTTRPDTLYGATFMVVAPDSALAQEIVSDEARPAFETYLDEVKKKSEIERQATDHE  308
               VFTTRPDTL+GAT+ V+AP+ AL + I + +   A   Y  +   KS++ R     E
Sbjct  242  DFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKE  301

Query  309  KTGVPLGVEATNPVNGAKVPVWAGDYVLADYGTGAIMAVPAHDQRDLDFARTYGIDVIPV  368
            KTGV  G  A NPVNG  +PVW +DYVLA YGTGAIMAVPAHD+RD +FA+ + +D+IPV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  369  IDTGEADPRESGVATTGDGAYQNSGFLDGIATKTEAIATMCEFLGEKGIGEPTITYRLRD  428
            ++ G+ +      A T DG   NS+FLDG+  K+ AIA M E L   G+G+  +TYRLRD
Sbjct  362  LEGGNVE----EAAFTEDGLHINSDFLDGLD-KASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  429  WLLSRQRFWGCPIPIIHCESCGDVPVPDDQLPVKLPDLRGAELAPKGTSPLAGEEASEWR  488
            WL+SRQR+WG PIPIIH E     +VP+ +LP+ LP  ++   +  G SPLA  + ++W 
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLA--NVTDWL  474

Query  489  SVACPSCGGAAQRDTDTMDTFVDSSWYFMRYCCPHYDKGPFDVEAVRRWMPVAQYIGGVE  548
             V+    G  ++R+T+TM    +SSWY++RY  PH      D E +++W+PV  Y+GG E
Sbjct  475  EVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAE  533

Query  549  HATMHLLYSRFFTKVLHDLGMVDFTEPFQRLMNQGQVIN----EGRA-------------  591
            HA +HLLY+RF  KVL DLG+V   EPFQ+L NQG ++     ++R+             
Sbjct  534  HAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDG  593

Query  592  -----------------MSKSLGNGVDLGKQIDEFGVDAVRTTVIFAGPPDEDIDWADVS  634
                             MSKSL N V+ +  ++++G D++R   +F GP D  I W++ +
Sbjct  594  SFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEG  653

Query  635  PASTLKFLQRAWRVASEVTSDPDADLTQGDSTLRRVTHRSIADITELLEGGRYNVVVARI  694
              ++ KFL+R  R+   +T+   ++  +  ++L +V + ++  +TE ++  ++N  +A++
Sbjct  654  LEGSRKFLDRVYRL---ITTKEITE--ENSGALDKVYNETVKAVTEQVDQMKFNTAIAQL  708

Query  695  MELVNATRKAIDSGCGPADPAVREAVTFTAQALSLVAPYLAEEMWEML-GLEPSVANSHW  753
            M +VNA+ K      + A   V+    F        AP L+EE+W+ L +   S++   W
Sbjct  709  MVFVNAANKEDKLFSDYAKGFVQLIAPF--------APHLGEELWQALTASGESISYVPW  760

Query  754  PTADEKLLVADKVTMVVQVTGKVRAKLTVSPDITEAEAREVALADVNVQRFTEGKEIVKI  813
            P+ DE  LV + V +VVQ+ GKV+AKL V+ D++  E +EVALA+ +VQ    GK+I+K+
Sbjct  761  PSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKV  820

Query  814  IAKLPKMISIVAK  826
            IA   K+++IV K
Sbjct  821  IAVPNKLVNIVIK  833

1024) leuS in NC_016511


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  550 bits (2077),  Expect = 1e-157, Method: Compositional matrix adjust.
 Identities = 350/853 (42%), Positives = 533/853 (63%), Gaps = 60/853 (7%)

Query  11   YDAVAAQEKWSKYWEEHRTFASLDDGSRERRYVLDMFAYPSG-DLHMGHAEAFAIGDVLA  69
            YD  A + KW  +W +++TF +  D+S+ + Y LDMF+YPSG +LH+GH+E+++  D+L+
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  70   RYWRLRGFDVLHPVGWDSFGLPAENAAIKHGTHPAEWTYRNIDTQAASFKRYAVSFDWSM  129
            R+ R +G +VLHP+GWD+FGLPAE+ A+  G +PAE T  NI      ++  + S+DW  
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  130  RLHTSDEEYYRWTQWLFNRFFEKGLAYRKDSWANWCPNDQTVLANEQV-KDGCCERCGAV  188
             ++T+D +YY+WTQW+F +++EKGLAY  +   NW  +  T +ANE+V  DG  ER G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  189  VTKRQLNQWYFRITDYAQRLLDDMDQIEGKWPERVLSMQRNWIGRSEGAYVDFTIDGRKE  248
            V ++ + QW ++IT YA+RLL+D+++++  WPE +  MQRNWIG+S GA V F + +   
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD--WPESIKDMQRNWIGKSTGANVTFKVKDTDK  241

Query  249  PVRVFTTRPDTLYGATFMVVAPDSALAQEIVSDEARPAFETYLDEVKKKSEIERQATDHE  308
               VFTTRPDTL+GAT+ V+AP+ AL + I + +   A   Y  +   KS++ R     E
Sbjct  242  DFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKE  301

Query  309  KTGVPLGVEATNPVNGAKVPVWAGDYVLADYGTGAIMAVPAHDQRDLDFARTYGIDVIPV  368
            KTGV  G  A NPVNG  +PVW +DYVLA YGTGAIMAVPAHD+RD +FA+ + +D+IPV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  369  IDTGEADPRESGVATTGDGAYQNSGFLDGIATKTEAIATMCEFLGEKGIGEPTITYRLRD  428
            ++ G+ +      A T DG   NS+FLDG+  K+ AIA M E L   G+G+  +TYRLRD
Sbjct  362  LEGGNVE----EAAFTEDGLHINSDFLDGLD-KASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  429  WLLSRQRFWGCPIPIIHCESCGDVPVPDDQLPVKLPDLRGAELAPKGTSPLAGEEASEWR  488
            WL+SRQR+WG PIPIIH E     +VP+ +LP+ LP  ++   +  G SPLA  + ++W 
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLA--NVTDWL  474

Query  489  SVACPSCGGAAQRDTDTMDTFVDSSWYFMRYCCPHYDKGPFDVEAVRRWMPVAQYIGGVE  548
             V+    G  ++R+T+TM    +SSWY++RY  PH      D E +++W+PV  Y+GG E
Sbjct  475  EVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAE  533

Query  549  HATMHLLYSRFFTKVLHDLGMVDFTEPFQRLMNQGQVIN----EGRA-------------  591
            HA +HLLY+RF  KVL DLG+V   EPFQ+L NQG ++     ++R+             
Sbjct  534  HAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDG  593

Query  592  -----------------MSKSLGNGVDLGKQIDEFGVDAVRTTVIFAGPPDEDIDWADVS  634
                             MSKSL N V+ +  ++++G D++R   +F GP D  I W++ +
Sbjct  594  SFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEG  653

Query  635  PASTLKFLQRAWRVASEVTSDPDADLTQGDSTLRRVTHRSIADITELLEGGRYNVVVARI  694
              ++ KFL+R  R+   +T+   ++  +  ++L +V + ++  +TE ++  ++N  +A++
Sbjct  654  LEGSRKFLDRVYRL---ITTKEITE--ENSGALDKVYNETVKAVTEQVDQMKFNTAIAQL  708

Query  695  MELVNATRKAIDSGCGPADPAVREAVTFTAQALSLVAPYLAEEMWEML-GLEPSVANSHW  753
            M +VNA+ K      + A   V+    F        AP L+EE+W+ L +   S++   W
Sbjct  709  MVFVNAANKEDKLFSDYAKGFVQLIAPF--------APHLGEELWQALTASGESISYVPW  760

Query  754  PTADEKLLVADKVTMVVQVTGKVRAKLTVSPDITEAEAREVALADVNVQRFTEGKEIVKI  813
            P+ DE  LV + V +VVQ+ GKV+AKL V+ D++  E +EVALA+ +VQ    GK+I+K+
Sbjct  761  PSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKV  820

Query  814  IAKLPKMISIVAK  826
            IA   K+++IV K
Sbjct  821  IAVPNKLVNIVIK  833

1025) leuS in NC_016516


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  550 bits (2077),  Expect = 1e-157, Method: Compositional matrix adjust.
 Identities = 350/853 (42%), Positives = 533/853 (63%), Gaps = 60/853 (7%)

Query  11   YDAVAAQEKWSKYWEEHRTFASLDDGSRERRYVLDMFAYPSG-DLHMGHAEAFAIGDVLA  69
            YD  A + KW  +W +++TF +  D+S+ + Y LDMF+YPSG +LH+GH+E+++  D+L+
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  70   RYWRLRGFDVLHPVGWDSFGLPAENAAIKHGTHPAEWTYRNIDTQAASFKRYAVSFDWSM  129
            R+ R +G +VLHP+GWD+FGLPAE+ A+  G +PAE T  NI      ++  + S+DW  
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  130  RLHTSDEEYYRWTQWLFNRFFEKGLAYRKDSWANWCPNDQTVLANEQV-KDGCCERCGAV  188
             ++T+D +YY+WTQW+F +++EKGLAY  +   NW  +  T +ANE+V  DG  ER G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  189  VTKRQLNQWYFRITDYAQRLLDDMDQIEGKWPERVLSMQRNWIGRSEGAYVDFTIDGRKE  248
            V ++ + QW ++IT YA+RLL+D+++++  WPE +  MQRNWIG+S GA V F + +   
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD--WPESIKDMQRNWIGKSTGANVTFKVKDTDK  241

Query  249  PVRVFTTRPDTLYGATFMVVAPDSALAQEIVSDEARPAFETYLDEVKKKSEIERQATDHE  308
               VFTTRPDTL+GAT+ V+AP+ AL + I + +   A   Y  +   KS++ R     E
Sbjct  242  DFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKE  301

Query  309  KTGVPLGVEATNPVNGAKVPVWAGDYVLADYGTGAIMAVPAHDQRDLDFARTYGIDVIPV  368
            KTGV  G  A NPVNG  +PVW +DYVLA YGTGAIMAVPAHD+RD +FA+ + +D+IPV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  369  IDTGEADPRESGVATTGDGAYQNSGFLDGIATKTEAIATMCEFLGEKGIGEPTITYRLRD  428
            ++ G+ +      A T DG   NS+FLDG+  K+ AIA M E L   G+G+  +TYRLRD
Sbjct  362  LEGGNVE----EAAFTEDGLHINSDFLDGLD-KASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  429  WLLSRQRFWGCPIPIIHCESCGDVPVPDDQLPVKLPDLRGAELAPKGTSPLAGEEASEWR  488
            WL+SRQR+WG PIPIIH E     +VP+ +LP+ LP  ++   +  G SPLA  + ++W 
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLA--NVTDWL  474

Query  489  SVACPSCGGAAQRDTDTMDTFVDSSWYFMRYCCPHYDKGPFDVEAVRRWMPVAQYIGGVE  548
             V+    G  ++R+T+TM    +SSWY++RY  PH      D E +++W+PV  Y+GG E
Sbjct  475  EVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAE  533

Query  549  HATMHLLYSRFFTKVLHDLGMVDFTEPFQRLMNQGQVIN----EGRA-------------  591
            HA +HLLY+RF  KVL DLG+V   EPFQ+L NQG ++     ++R+             
Sbjct  534  HAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDG  593

Query  592  -----------------MSKSLGNGVDLGKQIDEFGVDAVRTTVIFAGPPDEDIDWADVS  634
                             MSKSL N V+ +  ++++G D++R   +F GP D  I W++ +
Sbjct  594  SFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEG  653

Query  635  PASTLKFLQRAWRVASEVTSDPDADLTQGDSTLRRVTHRSIADITELLEGGRYNVVVARI  694
              ++ KFL+R  R+   +T+   ++  +  ++L +V + ++  +TE ++  ++N  +A++
Sbjct  654  LEGSRKFLDRVYRL---ITTKEITE--ENSGALDKVYNETVKAVTEQVDQMKFNTAIAQL  708

Query  695  MELVNATRKAIDSGCGPADPAVREAVTFTAQALSLVAPYLAEEMWEML-GLEPSVANSHW  753
            M +VNA+ K      + A   V+    F        AP L+EE+W+ L +   S++   W
Sbjct  709  MVFVNAANKEDKLFSDYAKGFVQLIAPF--------APHLGEELWQALTASGESISYVPW  760

Query  754  PTADEKLLVADKVTMVVQVTGKVRAKLTVSPDITEAEAREVALADVNVQRFTEGKEIVKI  813
            P+ DE  LV + V +VVQ+ GKV+AKL V+ D++  E +EVALA+ +VQ    GK+I+K+
Sbjct  761  PSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKV  820

Query  814  IAKLPKMISIVAK  826
            IA   K+++IV K
Sbjct  821  IAVPNKLVNIVIK  833

1026) Tsac_0122 in NC_017992


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  550 bits (2075),  Expect = 2e-157, Method: Compositional matrix adjust.
 Identities = 379/846 (45%), Positives = 543/846 (65%), Gaps = 57/846 (6%)

Query  6    DIDKKWQKKWEDTKLYKFNPDNIDKKLYCLEMFSYPSGAKLHAGHWYNYGPADSWARMKR  65
             I+ KWQ  W D   +K   D    K+Y L+MF+YPSGA LH GH   Y ++D  +R KR
Sbjct  8    AIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSRFKR  67

Query  66   MQGYEVFHPMGFDAFGLPAENYAIKTGIHPQDSTLQNIKTMERQLREMGATFDWDYEVIT  125
             QG +V+HPMG DAFGLPAE+YA+ TG +P + T +NI    RQ+  +G ++DWD EV T
Sbjct  68   AQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDREVNT  127

Query  126  CLPDYYKWTQWVFLQLYKKGLAYRKKAPVNWCPSCKTVLANEQVV-EGTCERCGSEVTKK  184
              P+YYKWTQW+F +LY KGLAY    PVNW     T +ANE+V+ +GT ER G  V +K
Sbjct  128  TDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRK  187

Query  185  DLTQWFLKITEYAeelldkldeldWPEKTKMMQRNWIGKSDGAEIEFKVDGKDISFKVFT  244
             + QW LKIT YAE LL+ L+E+DWPE  K MQRNWIGKS GA++ FKV + D  F VFT
Sbjct  188  PMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFT  247

Query  245  TRADTLYGVTYVVLAPENEIVDLITTDEHRRNVEDYKEYAKKQSEIERLSTEKEKTGVFT  304
            TR+DTL+G TY VLAPE+ +VD ITT ++   V DYK  A  +S++ R    KEKTGV T
Sbjct  248  TRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVWT  307

Query  305  GAYAIHPITGERVPIWISDYVLATYGTGCVMAVPAHDERDYAFAKKYDLPIKRVIKGNDG  364
            G+YAI+P+ G  +P+WI+DYVLA+YGTG +MAVPAHDERD  FAK+++L I  V+ G + 
Sbjct  308  GSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGN-  366

Query  365  VDDSLPFVEYGILVDSGDFTGSKSEDARIEIVKTLEKEGKGALKVNYRLRDWLVSRQRYW  424
            V+++ +F E G+ ++S+ + G     A   +V  LE EG G  +V YRLRDWL SRQRYW
Sbjct  367  VEEA-AFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYW  425

Query  425  GAPIPIIHCEKCGlvpvpeedlpvllpYNVEFSPD--GESPLKKSEEFMNTTCPKCGGKA  482
            G PIPIIH E     +VPE +LP++LP   ++ P   GESPL +  + ++ T    G K+
Sbjct  426  GEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED-GVKG  484

Query  483  LRDPDTLDTFVDSSWYFLRYPDNKNEKEPFNKELIDKMLPVDKYIGGAEHACMHLLYARF  542
             R+ +T+    +SSWY+LRY D  N     + EL+ + LPVD Y+GGAEHA +HLLYARF
Sbjct  485  RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARF  544

Query  543  VTKALRDLGYLDFDEPFKSLIHQGIILGP-------------------------------  571
              K L DLG +   EPF+ L++QG+ILG                                
Sbjct  545  WHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEEL  604

Query  572  --DGNKMSKSRGNTISPDEYINEYGSDVFRMYLMFGFAFTEGGPWNDDGIKAMSRFIQRI  629
                 KMSKS  N ++PD+ +++YG+D +R+Y MF  ++  + +W+++G+ +  +F++R+
Sbjct  605  EQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRV  664

Query  630  ERLVDKFiedkgkeskdeiskdekeLNYVRNYTIKSVTEDAEKFQFNTAIARIMELVNAL  689
             RL+           K+    +   L+ V N T+K+VTE+ ++ +FNTAIA++M +VNA 
Sbjct  665  YRLITT---------KEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNA-  714

Query  690  YKYDADVEIKNTRLYEETVADLIRLLAPFAPHFAEEMWEKI-GYGYSVFNQKWPKYDEKA  748
                     K+ +L+ +   ++++L+APFAPH++EE+W+ + + G S+    WP YDE  
Sbjct  715  -------ANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESK  767

Query  749  LVKDAIEIAVQVNGKVRGRLEISPDASEKEIQDTALSAESIKQYIDGKEivkivvvkGRL  808
            LV + +EI VQ++GKV+++L ++ D S  E+Q+ AL+ E ++  I GK+I+K++ V  +L
Sbjct  768  LVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKL  827

Query  809  VNIVVK  814
            VNIV+K
Sbjct  828  VNIVIK  833

1027) Tmari_0166 in NC_021214


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  550 bits (2075),  Expect = 2e-157, Method: Compositional matrix adjust.
 Identities = 368/841 (44%), Positives = 534/841 (64%), Gaps = 70/841 (8%)

Query  23   FYTPQRSEKPKYYALVMFPYPSGT-LHVGHVKNYVIGDIVARYKRMRGYNVLHPFGYDAF  81
            F T   + KPK+YAL MFPYPSG+ LHVGH   Y   DI++R+KR +G NVLHP G DAF
Sbjct  23   FKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSRFKRAQGHNVLHPMGWDAF  82

Query  82   GLPAENAAIEKGIHPEEWTRKNIATIRQQVKKLGISYDWSREIATCDEEYYKWTQWIFLQ  141
            GLPAE+ A++ G +P E T  NIA +++Q++ LG+SYDW RE+ T D +YYKWTQWIF +
Sbjct  83   GLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTK  142

Query  142  LYKNGLAYKKKAAVNWCPKCKTVLANEQV-KDGKCERCGTSVTIRHLEQWFFKITDYAER  200
            LY +GLAY    +VNW     T +ANE+V  DG  ER G +V  + + QW +KIT YAER
Sbjct  143  LYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAER  202

Query  201  LLNDLDKLTGWPEHVKTMQRNWIGKSTGAEIDFPVEGSDTKIRVFTTRPDTLWGVTFMal  260
            LL+DL+ + +WPE +K MQRNWIGKSTGA++ F V ++D  + VFTTRPDTL G T+  L
Sbjct  203  LLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVL  261

Query  261  apesplveelvpeekkeelqefleRVKQQDRFRRTSVEAEKEGFFLGRYAINPVTGERIP  320
            APE +LV+ +   ++ E + ++  +   +  + RT +  EK G   G YAINPV G  +P
Sbjct  262  APEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAINPVNGKEMP  321

Query  321  IYVANYILMEYGTGAIMGVPAHDQRDFSFAKKYGIPIKVVIKPADKDLDPEKMEEAYEGE  380
            + +A+Y+L  YGTGAIM+VPAHD+RD  FAK++ + I  V+  ++ +      E A+  +
Sbjct  322  VWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVE------EAAFTED  375

Query  381  GIMVNSGPFDGTPSSEGIEKVINWLEEKGIGKRSVQYKLRDWLISRQRYWGAPIPIIYCE  440
            G+ +NS+ +DG   + +I K+++WLE  G+G+ +V Y+LRDWL+SRQRYWG PIPII  E
Sbjct  376  GLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWE  435

Query  441  KCGVVPVPEEDLPVRLP--KDVEFLPTGQSPLSFHEGFKKTKCPVCGGEAQRETDTMDTF  498
                 +VPE +LP+ LP  KD+    TG+SPL+   +         G  ++RET+TM   
Sbjct  436  DGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRE-DGVKGRRETNTMPQW  494

Query  499  VDSSWYFLRYVNPHLEDKPFEPDDVNYWLPVDQYIGGVEHAVLHLLYSRFVTKVLHDLGY  558
             +SSWY+LRY++PH  +K  + + ++ WLPVD Y+GG EHAVLHLLY+RF  KVL DLG 
Sbjct  495  AGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGV  554

Query  559  LNFDEPFTNLFTQGMI----YKDG------------------------------AKMSKS  584
            +   EPF +LF QGMI    Y+D+                              AKMSKS
Sbjct  555  VPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKS  614

Query  585  KGNVVSPDEMIEKYGADTLRMYILFMAPPEKDAEWSDAGIEGVHRFVKRLWNTFYTVLPF  644
              NVV+PD+++E+YGADTLR+Y +FM+P +    WS+ G+EG ++F+ R+    Y ++  
Sbjct  615  LKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRV----YRLIT-  669

Query  645  VKEENTENLVLKNSTEKELRRKLHSIIKKITEDIEGGFKFNTAISGLMELVNHLSQYLNS  704
             KE       + +     L +  +  +K +TE+++   KFNTAI+ LM        ++N+
Sbjct  670  TKE-------ITEENSGALDKVYNETVKAVTEQVD-QMKFNTAIAQLM-------VFVNA  714

Query  705  VPQEEWNRKLLREIVEKLTLALSPFAPHLAEEFWHDLGNDSLVVQ-QSWPSYDPKALEVE  763
              +E+   KL+ +    +   ++PFAPHL+EE+W+ L   +  +   +WPSYD   L  +
Sbjct  715  ANKED---KLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVEN  771

Query  764  EVEIAIQINGKVRDKVVVPVDISEEDLKRIVLERERVKEYVDGKPIRKFIYVKGRIVNIV  823
            +VEI +QI+GKV+ K+VV+ D+S E+L+ + L  E+V+  + GK I K I V  ++VNIV
Sbjct  772  DVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIV  831

Query  824  V  824
            +
Sbjct  832  I  832

1028) leuS in NC_000853


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  550 bits (2075),  Expect = 2e-157, Method: Compositional matrix adjust.
 Identities = 368/841 (44%), Positives = 534/841 (64%), Gaps = 70/841 (8%)

Query  23   FYTPQRSEKPKYYALVMFPYPSGT-LHVGHVKNYVIGDIVARYKRMRGYNVLHPFGYDAF  81
            F T   + KPK+YAL MFPYPSG+ LHVGH   Y   DI++R+KR +G NVLHP G DAF
Sbjct  23   FKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSRFKRAQGHNVLHPMGWDAF  82

Query  82   GLPAENAAIEKGIHPEEWTRKNIATIRQQVKKLGISYDWSREIATCDEEYYKWTQWIFLQ  141
            GLPAE+ A++ G +P E T  NIA +++Q++ LG+SYDW RE+ T D +YYKWTQWIF +
Sbjct  83   GLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTK  142

Query  142  LYKNGLAYKKKAAVNWCPKCKTVLANEQV-KDGKCERCGTSVTIRHLEQWFFKITDYAER  200
            LY +GLAY    +VNW     T +ANE+V  DG  ER G +V  + + QW +KIT YAER
Sbjct  143  LYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAER  202

Query  201  LLNDLDKLTGWPEHVKTMQRNWIGKSTGAEIDFPVEGSDTKIRVFTTRPDTLWGVTFMal  260
            LL+DL+ + +WPE +K MQRNWIGKSTGA++ F V ++D  + VFTTRPDTL G T+  L
Sbjct  203  LLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVL  261

Query  261  apesplveelvpeekkeelqefleRVKQQDRFRRTSVEAEKEGFFLGRYAINPVTGERIP  320
            APE +LV+ +   ++ E + ++  +   +  + RT +  EK G   G YAINPV G  +P
Sbjct  262  APEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAINPVNGKEMP  321

Query  321  IYVANYILMEYGTGAIMGVPAHDQRDFSFAKKYGIPIKVVIKPADKDLDPEKMEEAYEGE  380
            + +A+Y+L  YGTGAIM+VPAHD+RD  FAK++ + I  V+  ++ +      E A+  +
Sbjct  322  VWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVE------EAAFTED  375

Query  381  GIMVNSGPFDGTPSSEGIEKVINWLEEKGIGKRSVQYKLRDWLISRQRYWGAPIPIIYCE  440
            G+ +NS+ +DG   + +I K+++WLE  G+G+ +V Y+LRDWL+SRQRYWG PIPII  E
Sbjct  376  GLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWE  435

Query  441  KCGVVPVPEEDLPVRLP--KDVEFLPTGQSPLSFHEGFKKTKCPVCGGEAQRETDTMDTF  498
                 +VPE +LP+ LP  KD+    TG+SPL+   +         G  ++RET+TM   
Sbjct  436  DGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRE-DGVKGRRETNTMPQW  494

Query  499  VDSSWYFLRYVNPHLEDKPFEPDDVNYWLPVDQYIGGVEHAVLHLLYSRFVTKVLHDLGY  558
             +SSWY+LRY++PH  +K  + + ++ WLPVD Y+GG EHAVLHLLY+RF  KVL DLG 
Sbjct  495  AGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGV  554

Query  559  LNFDEPFTNLFTQGMI----YKDG------------------------------AKMSKS  584
            +   EPF +LF QGMI    Y+D+                              AKMSKS
Sbjct  555  VPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKS  614

Query  585  KGNVVSPDEMIEKYGADTLRMYILFMAPPEKDAEWSDAGIEGVHRFVKRLWNTFYTVLPF  644
              NVV+PD+++E+YGADTLR+Y +FM+P +    WS+ G+EG ++F+ R+    Y ++  
Sbjct  615  LKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRV----YRLIT-  669

Query  645  VKEENTENLVLKNSTEKELRRKLHSIIKKITEDIEGGFKFNTAISGLMELVNHLSQYLNS  704
             KE       + +     L +  +  +K +TE+++   KFNTAI+ LM        ++N+
Sbjct  670  TKE-------ITEENSGALDKVYNETVKAVTEQVD-QMKFNTAIAQLM-------VFVNA  714

Query  705  VPQEEWNRKLLREIVEKLTLALSPFAPHLAEEFWHDLGNDSLVVQ-QSWPSYDPKALEVE  763
              +E+   KL+ +    +   ++PFAPHL+EE+W+ L   +  +   +WPSYD   L  +
Sbjct  715  ANKED---KLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVEN  771

Query  764  EVEIAIQINGKVRDKVVVPVDISEEDLKRIVLERERVKEYVDGKPIRKFIYVKGRIVNIV  823
            +VEI +QI+GKV+ K+VV+ D+S E+L+ + L  E+V+  + GK I K I V  ++VNIV
Sbjct  772  DVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIV  831

Query  824  V  824
            +
Sbjct  832  I  832

1029) Selin_0893 in NC_014836


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  550 bits (2075),  Expect = 2e-157, Method: Compositional matrix adjust.
 Identities = 351/854 (42%), Positives = 546/854 (64%), Gaps = 64/854 (7%)

Query  7    YQFGDIEPKWQDSWNSVGAFRALVDTSRPKFYCLEMLPYPSGR-IHMGHVRNYAIGDAIA  65
            Y+   IEPKWQ  W    +F++  D+S+PKFY L+M+PYPSG  +H+GH   Y+  D ++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  66   RYKKMRGYNVLHPMGWDAFGLPAENAAIAHNMDPGEWTWSNIAYMKQQLQKLGFSYDWER  125
            R+K+ +G NVLHPMGWDAFGLPAE+ A+    DP+E T  NIA  K+Q++ LGFSYDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  126  ELATCSEEYAAFEQQLFIELYKKGLIYRKKAEVNWCDHCKTVLANEQV-EEGRCWRDGSE  184
            E+ T   +Y    Q +F  LY KGL Y     VNW ++  T +ANE+V  +G   R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  185  VLKKELEQWFFRITAYAdellegldtltdgWPERVLTMQRNWIGKSIGAEIVFEIPEISE  244
            V++K + QW ++ITAYA+ LLE+L+ +   WPE +  MQRNWIGKS GA++ F + +   
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD--WPESIKDMQRNWIGKSTGANVTFKVKDTDK  241

Query  245  SITVFTTRPDTLFGATFMTLAPEHPLALRLCAGKETEAGVKAFIEKVRRQDTITRTS-DK  303
             +TVFTTRPDTLFGAT+  LAPEH+L   + ++ ++EA V  +  +   +  ++RT   K
Sbjct  242  DFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEA-VADYKRQASLKSDLARTDLAK  300

Query  304  EKEGVFTGASAINPVNGQSIPVYLGNFVLMGYGTGAVMAVPAHDQRDFAFARKYQLPITE  363
            EK GV TG+ AINPVNG+ +PV ++++VL +YGTGA+MAVPAHD+RD  FA++++L I  
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  364  VIQSEQGVAGEAWTGPGTLINSGRFNGMDNETAKKAIIDHLQQQGKGTASINFRLRDWGI  423
            V+++ + V   A T  G  INS+ ++G+D+ +A   +++ L+ +G G  ++ +RLRDW +
Sbjct  361  VLEGGN-VEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLF  419

Query  424  SRQRYWGNPIPMIHCSQCGVVPVPADQLPVKLP--KGVTLQGSEESPLATVPEFVNVSCP  481
            SRQRYWG+PIP+IH  +    +VP  +LP+ LP  K++   G+ ESPLA V + ++V+  
Sbjct  420  SRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRE  479

Query  482  TCAGPARRETDTMDTFVESSWYFHRYACQEDKTQPINRQAMDYWMDVDQYIGGVEHAVMH  541
              +  +RRET+TM     SSWY+ RY   ++  +  + + +  W+ VD Y+GG EHAV+H
Sbjct  480  D-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLH  538

Query  542  LLYARFFHKALRDLGYVGSDEPFTRLLTQGMVL---------------------------  574
            LLYARF HK L DLG V + EPF +L+ QGM+L                           
Sbjct  539  LLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHV  598

Query  575  -------LGGKKMSKSLGNIVDPDEMIQRYGADTVRLFTLFASPPEKDLEWNESGVEGAF  627
                    +  KMSKSL N+V+PD+++++YGADT+R++ +F +P +  + W+E G+EG+ 
Sbjct  599  ETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSR  658

Query  628  RFLGRLWRLVHEDTTRYGRSAESPGELSDDARKLQQKLHQTIKRVTQNMEGHYHFNTAIA  687
            +FL+R+ RL+         + E++G        L++  ++T+K VT++++ +  FNTAIA
Sbjct  659  KFLDRVYRLITTKEI----TEENSGA-------LDKVYNETVKAVTEQVD-QMKFNTAIA  706

Query  688  ATMELVNEMTPFSDTSPSGKALFQEALEALCRLLAPFVPHICEELWQDLGHRSLLIN-EP  746
                   ++  F +++     LF +   ++ +L+APF PH+ EELWQ L   +  I+  P
Sbjct  707  -------QLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVP  759

Query  747  WPAFDPELASADEITLVVQVNGKVRAKIEVDAGIDKAQMQQLALEHERILPYLENVEIKQ  806
            WP++D      +++ +VVQ++GKV+AK+ V  ++ + ++Q++AL +E++ + +   +I +
Sbjct  760  WPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIK  819

Query  807  VIVVPGKLVNIVVK  820
            VI VP KLVNIV+K
Sbjct  820  VIAVPNKLVNIVIK  833

1030) leuS in NC_009257


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  550 bits (2075),  Expect = 2e-157, Method: Compositional matrix adjust.
 Identities = 355/856 (42%), Positives = 551/856 (65%), Gaps = 72/856 (8%)

Query  4    YNFSDIEKSTQEYWRKNDTFKTIEDNTKEKFYCLSMLPYPSGT-LHMGHVRNYTIGDVIA  62
            Y+ + IE   Q +W  N+TFKT  D +K KFY L M+PYPSG+ LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYQKMQGKNVLHPMGWDAFGLPAENAAIKHKKSPYEWTKSNIAYMRSQFDSLGFSFDWSR  122
            R+++ QG NVLHPMGWDAFGLPAE+ A+   + P E T  NIA  + Q+++LGFS+DW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EIATCDEDYYKWEQWFFIQLYKKGLAYRKNSVVNW-DPVDQTVLANEQVVDGRGWRSGAL  181
            E+ T D +YYKW QW+F +LY KGLAY  +  VNW + ++ ++  +E + DG + R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VEKKEIPQWFLKITDYADELLQDINKLDNWPEAVKTMQINWIGKSKGLTVKFKVKDSNQE  241
            V +K + QW LKIT YA+ LL+D++ +D WPE++K MQ NWIGKS G  V FKVKD++++
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  242  IEVFTTRPDTLMGVNYLGIAPEHPLALKEAKSNSQLAAFIEECKKTSTMEADLA----TQ  297
            + VFTTRPDTL G  Y  +APEH+L   +A + S+ A  + + K+ +++ +DLA    ++
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALV--DAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  298  EKKGFKTSIKVIHPISAETIDVWVANFVLMGYGSGAVMSVPAHDQRDWEFAQKYNIPLKQ  357
            EK G  T+   I+P+++  + VW+A++VL +YG+GA+M+VPAHD+RDWEFA+++N+ +  
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  358  VIESNDNKLKIDLEKQAFTEKGILINSGEFDGLNFKNAYQAIKKYLTEQNKGYETTNFRI  417
            V+E+       ++E  AFTE G+ INS+ +DGL+  +A   +   L  +  G E   +R+
Sbjct  361  VLEGG------NVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRL  414

Query  418  HDWGISRQRYWGCPIPMIHCDDCGAVPEKEENLPVRLPTDVALTEAG---SPLKDIPEFI  474
            +DW +SRQRYWG PIP+IH +D  + +  E +LP+ LP    +  +G   SPL ++ + +
Sbjct  415  RDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWL  474

Query  475  NVACPECGKPAKRETDTFDTFFESSWYYARYTCPTANQMLDQEA--NYWLPVDKYIGGIE  532
            +V+  +  K ++RET+T      SSWYY RY  P   + L +E   + WLPVD Y+GG E
Sbjct  475  EVTREDGVK-GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAE  533

Query  533  HAIMHLLYARFFHKLMRDQGLVKSDEPFKNLLTQGMVL-------------------KDG  573
            HA++HLLYARF HK++ D G+V + EPF++L+ QGM+L                   +DG
Sbjct  534  HAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDG  593

Query  574  ---------------AKMSKSKGNIVDPQELIDKYGADTVRLFSMFAAPPEQSLEWSETG  618
                           AKMSKS  N+V+P++++++YGADT+R++ MF +P + S+ WSE G
Sbjct  594  SFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEG  653

Query  619  VEGANKFLRKVFNYAELNKVIFAKNITLESQKLTKEDKKARFEIHSNLKQAIFDFDKSQF  678
            +EG+ KFL +V+     + +   ++ +L+  K+ +E  KA   +  ++ Q  F+   +Q+
Sbjct  654  LEGSRKFLDRVYRLITTKEITEENSGALD--KVYNETVKA---VTEQVDQMKFNTAIAQL  708

Query  679  NTVVSACMKILNTLNNYDNLSESVKVEGFSILLRILAPFTPHLCHYLWQQLNL-GEDILH  737
               V+A  K  + +++Y +        GF   ++++APF+PHL + LWQ L   GE I  
Sbjct  709  MVFVNAANKEDKLFSDYAK--------GF---VQLIAPFAPHLGEELWQALTASGESISY  757

Query  738  TSFPIVDNNALEKDEFLLVVQINGKLKAKLELDASLSSNQVEEVVLADEHVKSFIDNKQV  797
             + P  D++ L  ++  +VVQI+GK+KAKL +   LS ++++EV LA+E V++ I  K++
Sbjct  758  VPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDI  817

Query  798  VKVIYVPQKLINIVIK  813
            +KVI VP+KL+NIVIK
Sbjct  818  IKVIAVPNKLVNIVIK  833

1031) leuS in NC_017534


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  550 bits (2075),  Expect = 2e-157, Method: Compositional matrix adjust.
 Identities = 350/853 (42%), Positives = 533/853 (63%), Gaps = 60/853 (7%)

Query  11   YDAVAAQEKWSKYWEEHRTFASLDDGSRERRYVLDMFAYPSG-DLHMGHAEAFAIGDVLA  69
            YD  A + KW  +W +++TF +  D+S+ + Y LDMF+YPSG +LH+GH+E+++  D+L+
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  70   RYWRLRGFDVLHPVGWDSFGLPAENAAIKHGTHPAEWTYRNIDTQAASFKRYAVSFDWSM  129
            R+ R +G +VLHP+GWD+FGLPAE+ A+  G +PAE T  NI      ++  + S+DW  
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  130  RLHTSDEEYYRWTQWLFNRFFEKGLAYRKDSWANWCPNDQTVLANEQV-KDGCCERCGAV  188
             ++T+D +YY+WTQW+F +++EKGLAY  +   NW  +  T +ANE+V  DG  ER G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  189  VTKRQLNQWYFRITDYAQRLLDDMDQIEGKWPERVLSMQRNWIGRSEGAYVDFTIDGRKE  248
            V ++ + QW ++IT YA+RLL+D+++++  WPE +  MQRNWIG+S GA V F + +   
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD--WPESIKDMQRNWIGKSTGANVTFKVKDTDK  241

Query  249  PVRVFTTRPDTLYGATFMVVAPDSALAQEIVSDEARPAFETYLDEVKKKSEIERQATDHE  308
               VFTTRPDTL+GAT+ V+AP+ AL + I + +   A   Y  +   KS++ R     E
Sbjct  242  DFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKE  301

Query  309  KTGVPLGVEATNPVNGAKVPVWAGDYVLADYGTGAIMAVPAHDQRDLDFARTYGIDVIPV  368
            KTGV  G  A NPVNG  +PVW +DYVLA YGTGAIMAVPAHD+RD +FA+ + +D+IPV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  369  IDTGEADPRESGVATTGDGAYQNSGFLDGIATKTEAIATMCEFLGKKGIGEPTITYRLRD  428
            ++ G+ +      A T DG   NS+FLDG+  K+ AIA M E L   G+G+  +TYRLRD
Sbjct  362  LEGGNVE----EAAFTEDGLHINSDFLDGLD-KASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  429  WLLSRQRFWGCPIPIIHCESCGDVPVPDDQLPVKLPDLRGAELAPKGTSPLAGEEASEWR  488
            WL+SRQR+WG PIPIIH E     +VP+ +LP+ LP  ++   +  G SPLA  + ++W 
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLA--NVTDWL  474

Query  489  SVACPSCGGAAQRDTDTMDTFVDSSWYFMRYCCPHYDKGPFDVEAVRRWMPVAQYIGGVE  548
             V+    G  ++R+T+TM    +SSWY++RY  PH      D E +++W+PV  Y+GG E
Sbjct  475  EVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAE  533

Query  549  HATMHLLYSRFFTKVLHDLGMVDFTEPFQRLMNQGQVIN----EGRA-------------  591
            HA +HLLY+RF  KVL DLG+V   EPFQ+L NQG ++     ++R+             
Sbjct  534  HAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDG  593

Query  592  -----------------MSKSLGNGVDLGKQIDEFGVDAVRTTVIFAGPPDEDIDWADVS  634
                             MSKSL N V+ +  ++++G D++R   +F GP D  I W++ +
Sbjct  594  SFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEG  653

Query  635  PASTLKFLQRAWRVASEVTSDPDADLTQGDSTLRRVTHRSIADITELLEGGRYNVVVARI  694
              ++ KFL+R  R+   +T+   ++  +  ++L +V + ++  +TE ++  ++N  +A++
Sbjct  654  LEGSRKFLDRVYRL---ITTKEITE--ENSGALDKVYNETVKAVTEQVDQMKFNTAIAQL  708

Query  695  MELVNATRKAIDSGCGPADPAVREAVTFTAQALSLVAPYLAEEMWEML-GLEPSVANSHW  753
            M +VNA+ K      + A   V+    F        AP L+EE+W+ L +   S++   W
Sbjct  709  MVFVNAANKEDKLFSDYAKGFVQLIAPF--------APHLGEELWQALTASGESISYVPW  760

Query  754  PTADEKLLVADKVTMVVQVTGKVRAKLTVSPDITEAEAREVALADVNVQRFTEGKEIVKI  813
            P+ DE  LV + V +VVQ+ GKV+AKL V+ D++  E +EVALA+ +VQ    GK+I+K+
Sbjct  761  PSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKV  820

Query  814  IAKLPKMISIVAK  826
            IA   K+++IV K
Sbjct  821  IAVPNKLVNIVIK  833

1032) leuS in NC_018707


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  550 bits (2075),  Expect = 2e-157, Method: Compositional matrix adjust.
 Identities = 350/853 (42%), Positives = 533/853 (63%), Gaps = 60/853 (7%)

Query  11   YDAVAAQEKWSKYWEEHRTFASLDDGSRERRYVLDMFAYPSG-DLHMGHAEAFAIGDVLA  69
            YD  A + KW  +W +++TF +  D+S+ + Y LDMF+YPSG +LH+GH+E+++  D+L+
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  70   RYWRLRGFDVLHPVGWDSFGLPAENAAIKHGTHPAEWTYRNIDTQAASFKRYAVSFDWSM  129
            R+ R +G +VLHP+GWD+FGLPAE+ A+  G +PAE T  NI      ++  + S+DW  
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  130  RLHTSDEEYYRWTQWLFNRFFEKGLAYRKDSWANWCPNDQTVLANEQV-KDGCCERCGAV  188
             ++T+D +YY+WTQW+F +++EKGLAY  +   NW  +  T +ANE+V  DG  ER G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  189  VTKRQLNQWYFRITDYAQRLLDDMDQIEGKWPERVLSMQRNWIGRSEGAYVDFTIDGRKE  248
            V ++ + QW ++IT YA+RLL+D+++++  WPE +  MQRNWIG+S GA V F + +   
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD--WPESIKDMQRNWIGKSTGANVTFKVKDTDK  241

Query  249  PVRVFTTRPDTLYGATFMVVAPDSALAQEIVSDEARPAFETYLDEVKKKSEIERQATDHE  308
               VFTTRPDTL+GAT+ V+AP+ AL + I + +   A   Y  +   KS++ R     E
Sbjct  242  DFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKE  301

Query  309  KTGVPLGVEATNPVNGAKVPVWAGDYVLADYGTGAIMAVPAHDQRDLDFARTYGIDVIPV  368
            KTGV  G  A NPVNG  +PVW +DYVLA YGTGAIMAVPAHD+RD +FA+ + +D+IPV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  369  IDTGEADPRESGVATTGDGAYQNSGFLDGIATKTEAIATMCEFLGKKGIGEPTITYRLRD  428
            ++ G+ +      A T DG   NS+FLDG+  K+ AIA M E L   G+G+  +TYRLRD
Sbjct  362  LEGGNVE----EAAFTEDGLHINSDFLDGLD-KASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  429  WLLSRQRFWGCPIPIIHCESCGDVPVPDDQLPVKLPDLRGAELAPKGTSPLAGEEASEWR  488
            WL+SRQR+WG PIPIIH E     +VP+ +LP+ LP  ++   +  G SPLA  + ++W 
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLA--NVTDWL  474

Query  489  SVACPSCGGAAQRDTDTMDTFVDSSWYFMRYCCPHYDKGPFDVEAVRRWMPVAQYIGGVE  548
             V+    G  ++R+T+TM    +SSWY++RY  PH      D E +++W+PV  Y+GG E
Sbjct  475  EVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAE  533

Query  549  HATMHLLYSRFFTKVLHDLGMVDFTEPFQRLMNQGQVIN----EGRA-------------  591
            HA +HLLY+RF  KVL DLG+V   EPFQ+L NQG ++     ++R+             
Sbjct  534  HAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDG  593

Query  592  -----------------MSKSLGNGVDLGKQIDEFGVDAVRTTVIFAGPPDEDIDWADVS  634
                             MSKSL N V+ +  ++++G D++R   +F GP D  I W++ +
Sbjct  594  SFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEG  653

Query  635  PASTLKFLQRAWRVASEVTSDPDADLTQGDSTLRRVTHRSIADITELLEGGRYNVVVARI  694
              ++ KFL+R  R+   +T+   ++  +  ++L +V + ++  +TE ++  ++N  +A++
Sbjct  654  LEGSRKFLDRVYRL---ITTKEITE--ENSGALDKVYNETVKAVTEQVDQMKFNTAIAQL  708

Query  695  MELVNATRKAIDSGCGPADPAVREAVTFTAQALSLVAPYLAEEMWEML-GLEPSVANSHW  753
            M +VNA+ K      + A   V+    F        AP L+EE+W+ L +   S++   W
Sbjct  709  MVFVNAANKEDKLFSDYAKGFVQLIAPF--------APHLGEELWQALTASGESISYVPW  760

Query  754  PTADEKLLVADKVTMVVQVTGKVRAKLTVSPDITEAEAREVALADVNVQRFTEGKEIVKI  813
            P+ DE  LV + V +VVQ+ GKV+AKL V+ D++  E +EVALA+ +VQ    GK+I+K+
Sbjct  761  PSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKV  820

Query  814  IAKLPKMISIVAK  826
            IA   K+++IV K
Sbjct  821  IAVPNKLVNIVIK  833

1033) PAGK_1257 in NC_021085


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  550 bits (2075),  Expect = 2e-157, Method: Compositional matrix adjust.
 Identities = 350/853 (42%), Positives = 533/853 (63%), Gaps = 60/853 (7%)

Query  11   YDAVAAQEKWSKYWEEHRTFASLDDGSRERRYVLDMFAYPSG-DLHMGHAEAFAIGDVLA  69
            YD  A + KW  +W +++TF +  D+S+ + Y LDMF+YPSG +LH+GH+E+++  D+L+
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  70   RYWRLRGFDVLHPVGWDSFGLPAENAAIKHGTHPAEWTYRNIDTQAASFKRYAVSFDWSM  129
            R+ R +G +VLHP+GWD+FGLPAE+ A+  G +PAE T  NI      ++  + S+DW  
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  130  RLHTSDEEYYRWTQWLFNRFFEKGLAYRKDSWANWCPNDQTVLANEQV-KDGCCERCGAV  188
             ++T+D +YY+WTQW+F +++EKGLAY  +   NW  +  T +ANE+V  DG  ER G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  189  VTKRQLNQWYFRITDYAQRLLDDMDQIEGKWPERVLSMQRNWIGRSEGAYVDFTIDGRKE  248
            V ++ + QW ++IT YA+RLL+D+++++  WPE +  MQRNWIG+S GA V F + +   
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD--WPESIKDMQRNWIGKSTGANVTFKVKDTDK  241

Query  249  PVRVFTTRPDTLYGATFMVVAPDSALAQEIVSDEARPAFETYLDEVKKKSEIERQATDHE  308
               VFTTRPDTL+GAT+ V+AP+ AL + I + +   A   Y  +   KS++ R     E
Sbjct  242  DFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKE  301

Query  309  KTGVPLGVEATNPVNGAKVPVWAGDYVLADYGTGAIMAVPAHDQRDLDFARTYGIDVIPV  368
            KTGV  G  A NPVNG  +PVW +DYVLA YGTGAIMAVPAHD+RD +FA+ + +D+IPV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  369  IDTGEADPRESGVATTGDGAYQNSGFLDGIATKTEAIATMCEFLGKKGIGEPTITYRLRD  428
            ++ G+ +      A T DG   NS+FLDG+  K+ AIA M E L   G+G+  +TYRLRD
Sbjct  362  LEGGNVE----EAAFTEDGLHINSDFLDGLD-KASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  429  WLLSRQRFWGCPIPIIHCESCGDVPVPDDQLPVKLPDLRGAELAPKGTSPLAGEEASEWR  488
            WL+SRQR+WG PIPIIH E     +VP+ +LP+ LP  ++   +  G SPLA  + ++W 
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLA--NVTDWL  474

Query  489  SVACPSCGGAAQRDTDTMDTFVDSSWYFMRYCCPHYDKGPFDVEAVRRWMPVAQYIGGVE  548
             V+    G  ++R+T+TM    +SSWY++RY  PH      D E +++W+PV  Y+GG E
Sbjct  475  EVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAE  533

Query  549  HATMHLLYSRFFTKVLHDLGMVDFTEPFQRLMNQGQVIN----EGRA-------------  591
            HA +HLLY+RF  KVL DLG+V   EPFQ+L NQG ++     ++R+             
Sbjct  534  HAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDG  593

Query  592  -----------------MSKSLGNGVDLGKQIDEFGVDAVRTTVIFAGPPDEDIDWADVS  634
                             MSKSL N V+ +  ++++G D++R   +F GP D  I W++ +
Sbjct  594  SFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEG  653

Query  635  PASTLKFLQRAWRVASEVTSDPDADLTQGDSTLRRVTHRSIADITELLEGGRYNVVVARI  694
              ++ KFL+R  R+   +T+   ++  +  ++L +V + ++  +TE ++  ++N  +A++
Sbjct  654  LEGSRKFLDRVYRL---ITTKEITE--ENSGALDKVYNETVKAVTEQVDQMKFNTAIAQL  708

Query  695  MELVNATRKAIDSGCGPADPAVREAVTFTAQALSLVAPYLAEEMWEML-GLEPSVANSHW  753
            M +VNA+ K      + A   V+    F        AP L+EE+W+ L +   S++   W
Sbjct  709  MVFVNAANKEDKLFSDYAKGFVQLIAPF--------APHLGEELWQALTASGESISYVPW  760

Query  754  PTADEKLLVADKVTMVVQVTGKVRAKLTVSPDITEAEAREVALADVNVQRFTEGKEIVKI  813
            P+ DE  LV + V +VVQ+ GKV+AKL V+ D++  E +EVALA+ +VQ    GK+I+K+
Sbjct  761  PSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKV  820

Query  814  IAKLPKMISIVAK  826
            IA   K+++IV K
Sbjct  821  IAVPNKLVNIVIK  833

1034) leuS in NC_014039


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  550 bits (2075),  Expect = 2e-157, Method: Compositional matrix adjust.
 Identities = 350/853 (42%), Positives = 533/853 (63%), Gaps = 60/853 (7%)

Query  11   YDAVAAQEKWSKYWEEHRTFASLDDGSRERRYVLDMFAYPSG-DLHMGHAEAFAIGDVLA  69
            YD  A + KW  +W +++TF +  D+S+ + Y LDMF+YPSG +LH+GH+E+++  D+L+
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  70   RYWRLRGFDVLHPVGWDSFGLPAENAAIKHGTHPAEWTYRNIDTQAASFKRYAVSFDWSM  129
            R+ R +G +VLHP+GWD+FGLPAE+ A+  G +PAE T  NI      ++  + S+DW  
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  130  RLHTSDEEYYRWTQWLFNRFFEKGLAYRKDSWANWCPNDQTVLANEQV-KDGCCERCGAV  188
             ++T+D +YY+WTQW+F +++EKGLAY  +   NW  +  T +ANE+V  DG  ER G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  189  VTKRQLNQWYFRITDYAQRLLDDMDQIEGKWPERVLSMQRNWIGRSEGAYVDFTIDGRKE  248
            V ++ + QW ++IT YA+RLL+D+++++  WPE +  MQRNWIG+S GA V F + +   
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD--WPESIKDMQRNWIGKSTGANVTFKVKDTDK  241

Query  249  PVRVFTTRPDTLYGATFMVVAPDSALAQEIVSDEARPAFETYLDEVKKKSEIERQATDHE  308
               VFTTRPDTL+GAT+ V+AP+ AL + I + +   A   Y  +   KS++ R     E
Sbjct  242  DFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKE  301

Query  309  KTGVPLGVEATNPVNGAKVPVWAGDYVLADYGTGAIMAVPAHDQRDLDFARTYGIDVIPV  368
            KTGV  G  A NPVNG  +PVW +DYVLA YGTGAIMAVPAHD+RD +FA+ + +D+IPV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  369  IDTGEADPRESGVATTGDGAYQNSGFLDGIATKTEAIATMCEFLGKKGIGEPTITYRLRD  428
            ++ G+ +      A T DG   NS+FLDG+  K+ AIA M E L   G+G+  +TYRLRD
Sbjct  362  LEGGNVE----EAAFTEDGLHINSDFLDGLD-KASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  429  WLLSRQRFWGCPIPIIHCESCGDVPVPDDQLPVKLPDLRGAELAPKGTSPLAGEEASEWR  488
            WL+SRQR+WG PIPIIH E     +VP+ +LP+ LP  ++   +  G SPLA  + ++W 
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLA--NVTDWL  474

Query  489  SVACPSCGGAAQRDTDTMDTFVDSSWYFMRYCCPHYDKGPFDVEAVRRWMPVAQYIGGVE  548
             V+    G  ++R+T+TM    +SSWY++RY  PH      D E +++W+PV  Y+GG E
Sbjct  475  EVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAE  533

Query  549  HATMHLLYSRFFTKVLHDLGMVDFTEPFQRLMNQGQVIN----EGRA-------------  591
            HA +HLLY+RF  KVL DLG+V   EPFQ+L NQG ++     ++R+             
Sbjct  534  HAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDG  593

Query  592  -----------------MSKSLGNGVDLGKQIDEFGVDAVRTTVIFAGPPDEDIDWADVS  634
                             MSKSL N V+ +  ++++G D++R   +F GP D  I W++ +
Sbjct  594  SFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEG  653

Query  635  PASTLKFLQRAWRVASEVTSDPDADLTQGDSTLRRVTHRSIADITELLEGGRYNVVVARI  694
              ++ KFL+R  R+   +T+   ++  +  ++L +V + ++  +TE ++  ++N  +A++
Sbjct  654  LEGSRKFLDRVYRL---ITTKEITE--ENSGALDKVYNETVKAVTEQVDQMKFNTAIAQL  708

Query  695  MELVNATRKAIDSGCGPADPAVREAVTFTAQALSLVAPYLAEEMWEML-GLEPSVANSHW  753
            M +VNA+ K      + A   V+    F        AP L+EE+W+ L +   S++   W
Sbjct  709  MVFVNAANKEDKLFSDYAKGFVQLIAPF--------APHLGEELWQALTASGESISYVPW  760

Query  754  PTADEKLLVADKVTMVVQVTGKVRAKLTVSPDITEAEAREVALADVNVQRFTEGKEIVKI  813
            P+ DE  LV + V +VVQ+ GKV+AKL V+ D++  E +EVALA+ +VQ    GK+I+K+
Sbjct  761  PSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKV  820

Query  814  IAKLPKMISIVAK  826
            IA   K+++IV K
Sbjct  821  IAVPNKLVNIVIK  833

1035) leuS in NC_019537


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  549 bits (2074),  Expect = 2e-157, Method: Compositional matrix adjust.
 Identities = 354/856 (42%), Positives = 553/856 (65%), Gaps = 72/856 (8%)

Query  4    YNFSDIEKSTQEYWRKNDTFKTIEDNTKEKFYCLSMLPYPSGT-LHMGHVRNYTIGDVIA  62
            Y+ + IE   Q +W  N+TFKT  D +K KFY L M+PYPSG+ LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYQKMQGKNVLHPMGWDAFGLPAENAAIKHKKSPYEWTKSNIAYMRSQFDSLGFSFDWSR  122
            R+++ QG NVLHPMGWDAFGLPAE+ A+   + P E T  NIA  + Q+++LGFS+DW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EIATCDEDYYKWEQWFFIQLYKKGLAYRKNSVVNW-DPVDQTVLANEQVVDGRGWRSGAL  181
            E+ T D +YYKW QW+F +LY KGLAY  +  VNW + ++ ++  +E + DG + R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VEKKEIPQWFLKITDYADELLQDINKLDNWPEAVKTMQINWIGKSKGLTVKFKVKDSNQE  241
            V +K + QW LKIT YA+ LL+D++ +D WPE++K MQ NWIGKS G  V FKVKD++++
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  242  IEVFTTRPDTLMGVNYLGIAPEHPLALKEAKSNSQLAAFIEECKKTSTMEADLA----TQ  297
            + VFTTRPDTL G  Y  +APEH+L   +A + S+ A  + + K+ +++ +DLA    ++
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALV--DAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  298  EKKGFKTSIKVIHPISAETIDVWVANFVLMGYGSGAVMSVPAHDQRDWEFAQKYNIPLKQ  357
            EK G  T+   I+P+++  + VW+A++VL +YG+GA+M+VPAHD+RDWEFA+++N+ +  
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  358  VIESNDNKLKIDLEKQAFTEKGILINSGEFDGLNFKNAYQAIKKYLTKQNKGYETTNFRI  417
            V+E+       ++E  AFTE G+ INS+ +DGL+  +A   +   L  +  G E   +R+
Sbjct  361  VLEGG------NVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRL  414

Query  418  HDWGISRQRYWGCPIPMIHCDDCGAVPEKEENLPVRLPTDVALTEAG---SPLKDIPEFI  474
            +DW +SRQRYWG PIP+IH +D  + +  E +LP+ LP    +  +G   SPL ++ + +
Sbjct  415  RDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWL  474

Query  475  NVACPECGKPAKRETDTFDTFFESSWYYARYTCPTSNQMLDQEA--NYWLPVDKYIGGIE  532
            +V+  +  K ++RET+T      SSWYY RY  P + + L +E   + WLPVD Y+GG E
Sbjct  475  EVTREDGVK-GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAE  533

Query  533  HAIMHLLYARFFHKLMRDQGLVKSDEPFKNLLTQGMVL-------------------KDG  573
            HA++HLLYARF HK++ D G+V + EPF++L+ QGM+L                   +DG
Sbjct  534  HAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDG  593

Query  574  ---------------AKMSKSKGNIVDPQELIDKYGADTVRLFSMFAASPEQSLEWSETG  618
                           AKMSKS  N+V+P++++++YGADT+R++ MF ++ + S+ WSE G
Sbjct  594  SFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEG  653

Query  619  VEGANKFLRKVFNYAELNKVIFAKNITLESQKLTKEDKKARFEIHSNLKQAIFDFDKSQF  678
            +EG+ KFL +V+     + +   ++ +L+  K+ +E  KA   +  ++ Q  F+   +Q+
Sbjct  654  LEGSRKFLDRVYRLITTKEITEENSGALD--KVYNETVKA---VTEQVDQMKFNTAIAQL  708

Query  679  NTVVSACMKILNTLNNYDNLSESVKVEGFSILLRILAPFTPHLCHYLWQQLNL-GEDILH  737
               V+A  K  + +++Y +        GF   ++++APF+PHL + LWQ L   GE I  
Sbjct  709  MVFVNAANKEDKLFSDYAK--------GF---VQLIAPFAPHLGEELWQALTASGESISY  757

Query  738  TSFPTVDNNALEKDEFLLVVQINGKLKAKLELDASLSSNQVEEVVLADEHVKSFIDNKQV  797
             + P+ D++ L  ++  +VVQI+GK+KAKL +   LS ++++EV LA+E V++ I  K++
Sbjct  758  VPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDI  817

Query  798  VKVIYVPQKLINIVIK  813
            +KVI VP+KL+NIVIK
Sbjct  818  IKVIAVPNKLVNIVIK  833

1036) leuS in NC_019551


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  549 bits (2074),  Expect = 2e-157, Method: Compositional matrix adjust.
 Identities = 354/856 (42%), Positives = 553/856 (65%), Gaps = 72/856 (8%)

Query  4    YNFSDIEKSTQEYWRKNDTFKTIEDNTKEKFYCLSMLPYPSGT-LHMGHVRNYTIGDVIA  62
            Y+ + IE   Q +W  N+TFKT  D +K KFY L M+PYPSG+ LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYQKMQGKNVLHPMGWDAFGLPAENAAIKHKKSPYEWTKSNIAYMRSQFDSLGFSFDWSR  122
            R+++ QG NVLHPMGWDAFGLPAE+ A+   + P E T  NIA  + Q+++LGFS+DW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EIATCDEDYYKWEQWFFIQLYKKGLAYRKNSVVNW-DPVDQTVLANEQVVDGRGWRSGAL  181
            E+ T D +YYKW QW+F +LY KGLAY  +  VNW + ++ ++  +E + DG + R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VEKKEIPQWFLKITDYADELLQDINKLDNWPEAVKTMQINWIGKSKGLTVKFKVKDSNQE  241
            V +K + QW LKIT YA+ LL+D++ +D WPE++K MQ NWIGKS G  V FKVKD++++
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  242  IEVFTTRPDTLMGVNYLGIAPEHPLALKEAKSNSQLAAFIEECKKTSTMEADLA----TQ  297
            + VFTTRPDTL G  Y  +APEH+L   +A + S+ A  + + K+ +++ +DLA    ++
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALV--DAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  298  EKKGFKTSIKVIHPISAETIDVWVANFVLMGYGSGAVMSVPAHDQRDWEFAQKYNIPLKQ  357
            EK G  T+   I+P+++  + VW+A++VL +YG+GA+M+VPAHD+RDWEFA+++N+ +  
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  358  VIESNDNKLKIDLEKQAFTEKGILINSGEFDGLNFKNAYQAIKKYLTKQNKGYETTNFRI  417
            V+E+       ++E  AFTE G+ INS+ +DGL+  +A   +   L  +  G E   +R+
Sbjct  361  VLEGG------NVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRL  414

Query  418  HDWGISRQRYWGCPIPMIHCDDCGAVPEKEENLPVRLPTDVALTEAG---SPLKDIPEFI  474
            +DW +SRQRYWG PIP+IH +D  + +  E +LP+ LP    +  +G   SPL ++ + +
Sbjct  415  RDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWL  474

Query  475  NVACPECGKPAKRETDTFDTFFESSWYYARYTCPTSNQMLDQEA--NYWLPVDKYIGGIE  532
            +V+  +  K ++RET+T      SSWYY RY  P + + L +E   + WLPVD Y+GG E
Sbjct  475  EVTREDGVK-GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAE  533

Query  533  HAIMHLLYARFFHKLMRDQGLVKSDEPFKNLLTQGMVL-------------------KDG  573
            HA++HLLYARF HK++ D G+V + EPF++L+ QGM+L                   +DG
Sbjct  534  HAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDG  593

Query  574  ---------------AKMSKSKGNIVDPQELIDKYGADTVRLFSMFAASPEQSLEWSETG  618
                           AKMSKS  N+V+P++++++YGADT+R++ MF ++ + S+ WSE G
Sbjct  594  SFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEG  653

Query  619  VEGANKFLRKVFNYAELNKVIFAKNITLESQKLTKEDKKARFEIHSNLKQAIFDFDKSQF  678
            +EG+ KFL +V+     + +   ++ +L+  K+ +E  KA   +  ++ Q  F+   +Q+
Sbjct  654  LEGSRKFLDRVYRLITTKEITEENSGALD--KVYNETVKA---VTEQVDQMKFNTAIAQL  708

Query  679  NTVVSACMKILNTLNNYDNLSESVKVEGFSILLRILAPFTPHLCHYLWQQLNL-GEDILH  737
               V+A  K  + +++Y +        GF   ++++APF+PHL + LWQ L   GE I  
Sbjct  709  MVFVNAANKEDKLFSDYAK--------GF---VQLIAPFAPHLGEELWQALTASGESISY  757

Query  738  TSFPTVDNNALEKDEFLLVVQINGKLKAKLELDASLSSNQVEEVVLADEHVKSFIDNKQV  797
             + P+ D++ L  ++  +VVQI+GK+KAKL +   LS ++++EV LA+E V++ I  K++
Sbjct  758  VPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDI  817

Query  798  VKVIYVPQKLINIVIK  813
            +KVI VP+KL+NIVIK
Sbjct  818  IKVIAVPNKLVNIVIK  833

1037) leuS in NC_009749


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  549 bits (2074),  Expect = 2e-157, Method: Compositional matrix adjust.
 Identities = 354/856 (42%), Positives = 553/856 (65%), Gaps = 72/856 (8%)

Query  4    YNFSDIEKSTQEYWRKNDTFKTIEDNTKEKFYCLSMLPYPSGT-LHMGHVRNYTIGDVIA  62
            Y+ + IE   Q +W  N+TFKT  D +K KFY L M+PYPSG+ LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYQKMQGKNVLHPMGWDAFGLPAENAAIKHKKSPYEWTKSNIAYMRSQFDSLGFSFDWSR  122
            R+++ QG NVLHPMGWDAFGLPAE+ A+   + P E T  NIA  + Q+++LGFS+DW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EIATCDEDYYKWEQWFFIQLYKKGLAYRKNSVVNW-DPVDQTVLANEQVVDGRGWRSGAL  181
            E+ T D +YYKW QW+F +LY KGLAY  +  VNW + ++ ++  +E + DG + R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VEKKEIPQWFLKITDYADELLQDINKLDNWPEAVKTMQINWIGKSKGLTVKFKVKDSNQE  241
            V +K + QW LKIT YA+ LL+D++ +D WPE++K MQ NWIGKS G  V FKVKD++++
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  242  IEVFTTRPDTLMGVNYLGIAPEHPLALKEAKSNSQLAAFIEECKKTSTMEADLA----TQ  297
            + VFTTRPDTL G  Y  +APEH+L   +A + S+ A  + + K+ +++ +DLA    ++
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALV--DAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  298  EKKGFKTSIKVIHPISAETIDVWVANFVLMGYGSGAVMSVPAHDQRDWEFAQKYNIPLKQ  357
            EK G  T+   I+P+++  + VW+A++VL +YG+GA+M+VPAHD+RDWEFA+++N+ +  
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  358  VIESNDNKLKIDLEKQAFTEKGILINSGEFDGLNFKNAYQAIKKYLTKQNKGYETTNFRI  417
            V+E+       ++E  AFTE G+ INS+ +DGL+  +A   +   L  +  G E   +R+
Sbjct  361  VLEGG------NVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRL  414

Query  418  HDWGISRQRYWGCPIPMIHCDDCGAVPEKEENLPVRLPTDVALTEAG---SPLKDIPEFI  474
            +DW +SRQRYWG PIP+IH +D  + +  E +LP+ LP    +  +G   SPL ++ + +
Sbjct  415  RDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWL  474

Query  475  NVACPECGKPAKRETDTFDTFFESSWYYARYTCPTSNQMLDQEA--NYWLPVDKYIGGIE  532
            +V+  +  K ++RET+T      SSWYY RY  P + + L +E   + WLPVD Y+GG E
Sbjct  475  EVTREDGVK-GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAE  533

Query  533  HAIMHLLYARFFHKLMRDQGLVKSDEPFKNLLTQGMVL-------------------KDG  573
            HA++HLLYARF HK++ D G+V + EPF++L+ QGM+L                   +DG
Sbjct  534  HAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDG  593

Query  574  ---------------AKMSKSKGNIVDPQELIDKYGADTVRLFSMFAASPEQSLEWSETG  618
                           AKMSKS  N+V+P++++++YGADT+R++ MF ++ + S+ WSE G
Sbjct  594  SFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEG  653

Query  619  VEGANKFLRKVFNYAELNKVIFAKNITLESQKLTKEDKKARFEIHSNLKQAIFDFDKSQF  678
            +EG+ KFL +V+     + +   ++ +L+  K+ +E  KA   +  ++ Q  F+   +Q+
Sbjct  654  LEGSRKFLDRVYRLITTKEITEENSGALD--KVYNETVKA---VTEQVDQMKFNTAIAQL  708

Query  679  NTVVSACMKILNTLNNYDNLSESVKVEGFSILLRILAPFTPHLCHYLWQQLNL-GEDILH  737
               V+A  K  + +++Y +        GF   ++++APF+PHL + LWQ L   GE I  
Sbjct  709  MVFVNAANKEDKLFSDYAK--------GF---VQLIAPFAPHLGEELWQALTASGESISY  757

Query  738  TSFPTVDNNALEKDEFLLVVQINGKLKAKLELDASLSSNQVEEVVLADEHVKSFIDNKQV  797
             + P+ D++ L  ++  +VVQI+GK+KAKL +   LS ++++EV LA+E V++ I  K++
Sbjct  758  VPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDI  817

Query  798  VKVIYVPQKLINIVIK  813
            +KVI VP+KL+NIVIK
Sbjct  818  IKVIAVPNKLVNIVIK  833

1038) leuS in NC_007880


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  549 bits (2074),  Expect = 2e-157, Method: Compositional matrix adjust.
 Identities = 354/856 (42%), Positives = 553/856 (65%), Gaps = 72/856 (8%)

Query  4    YNFSDIEKSTQEYWRKNDTFKTIEDNTKEKFYCLSMLPYPSGT-LHMGHVRNYTIGDVIA  62
            Y+ + IE   Q +W  N+TFKT  D +K KFY L M+PYPSG+ LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYQKMQGKNVLHPMGWDAFGLPAENAAIKHKKSPYEWTKSNIAYMRSQFDSLGFSFDWSR  122
            R+++ QG NVLHPMGWDAFGLPAE+ A+   + P E T  NIA  + Q+++LGFS+DW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EIATCDEDYYKWEQWFFIQLYKKGLAYRKNSVVNW-DPVDQTVLANEQVVDGRGWRSGAL  181
            E+ T D +YYKW QW+F +LY KGLAY  +  VNW + ++ ++  +E + DG + R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VEKKEIPQWFLKITDYADELLQDINKLDNWPEAVKTMQINWIGKSKGLTVKFKVKDSNQE  241
            V +K + QW LKIT YA+ LL+D++ +D WPE++K MQ NWIGKS G  V FKVKD++++
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  242  IEVFTTRPDTLMGVNYLGIAPEHPLALKEAKSNSQLAAFIEECKKTSTMEADLA----TQ  297
            + VFTTRPDTL G  Y  +APEH+L   +A + S+ A  + + K+ +++ +DLA    ++
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALV--DAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  298  EKKGFKTSIKVIHPISAETIDVWVANFVLMGYGSGAVMSVPAHDQRDWEFAQKYNIPLKQ  357
            EK G  T+   I+P+++  + VW+A++VL +YG+GA+M+VPAHD+RDWEFA+++N+ +  
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  358  VIESNDNKLKIDLEKQAFTEKGILINSGEFDGLNFKNAYQAIKKYLTKQNKGYETTNFRI  417
            V+E+       ++E  AFTE G+ INS+ +DGL+  +A   +   L  +  G E   +R+
Sbjct  361  VLEGG------NVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRL  414

Query  418  HDWGISRQRYWGCPIPMIHCDDCGAVPEKEENLPVRLPTDVALTEAG---SPLKDIPEFI  474
            +DW +SRQRYWG PIP+IH +D  + +  E +LP+ LP    +  +G   SPL ++ + +
Sbjct  415  RDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWL  474

Query  475  NVACPECGKPAKRETDTFDTFFESSWYYARYTCPTSNQMLDQEA--NYWLPVDKYIGGIE  532
            +V+  +  K ++RET+T      SSWYY RY  P + + L +E   + WLPVD Y+GG E
Sbjct  475  EVTREDGVK-GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAE  533

Query  533  HAIMHLLYARFFHKLMRDQGLVKSDEPFKNLLTQGMVL-------------------KDG  573
            HA++HLLYARF HK++ D G+V + EPF++L+ QGM+L                   +DG
Sbjct  534  HAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDG  593

Query  574  ---------------AKMSKSKGNIVDPQELIDKYGADTVRLFSMFAASPEQSLEWSETG  618
                           AKMSKS  N+V+P++++++YGADT+R++ MF ++ + S+ WSE G
Sbjct  594  SFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEG  653

Query  619  VEGANKFLRKVFNYAELNKVIFAKNITLESQKLTKEDKKARFEIHSNLKQAIFDFDKSQF  678
            +EG+ KFL +V+     + +   ++ +L+  K+ +E  KA   +  ++ Q  F+   +Q+
Sbjct  654  LEGSRKFLDRVYRLITTKEITEENSGALD--KVYNETVKA---VTEQVDQMKFNTAIAQL  708

Query  679  NTVVSACMKILNTLNNYDNLSESVKVEGFSILLRILAPFTPHLCHYLWQQLNL-GEDILH  737
               V+A  K  + +++Y +        GF   ++++APF+PHL + LWQ L   GE I  
Sbjct  709  MVFVNAANKEDKLFSDYAK--------GF---VQLIAPFAPHLGEELWQALTASGESISY  757

Query  738  TSFPTVDNNALEKDEFLLVVQINGKLKAKLELDASLSSNQVEEVVLADEHVKSFIDNKQV  797
             + P+ D++ L  ++  +VVQI+GK+KAKL +   LS ++++EV LA+E V++ I  K++
Sbjct  758  VPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDI  817

Query  798  VKVIYVPQKLINIVIK  813
            +KVI VP+KL+NIVIK
Sbjct  818  IKVIAVPNKLVNIVIK  833

1039) leuS in NC_008369


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  549 bits (2074),  Expect = 2e-157, Method: Compositional matrix adjust.
 Identities = 354/856 (42%), Positives = 553/856 (65%), Gaps = 72/856 (8%)

Query  4    YNFSDIEKSTQEYWRKNDTFKTIEDNTKEKFYCLSMLPYPSGT-LHMGHVRNYTIGDVIA  62
            Y+ + IE   Q +W  N+TFKT  D +K KFY L M+PYPSG+ LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYQKMQGKNVLHPMGWDAFGLPAENAAIKHKKSPYEWTKSNIAYMRSQFDSLGFSFDWSR  122
            R+++ QG NVLHPMGWDAFGLPAE+ A+   + P E T  NIA  + Q+++LGFS+DW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EIATCDEDYYKWEQWFFIQLYKKGLAYRKNSVVNW-DPVDQTVLANEQVVDGRGWRSGAL  181
            E+ T D +YYKW QW+F +LY KGLAY  +  VNW + ++ ++  +E + DG + R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VEKKEIPQWFLKITDYADELLQDINKLDNWPEAVKTMQINWIGKSKGLTVKFKVKDSNQE  241
            V +K + QW LKIT YA+ LL+D++ +D WPE++K MQ NWIGKS G  V FKVKD++++
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  242  IEVFTTRPDTLMGVNYLGIAPEHPLALKEAKSNSQLAAFIEECKKTSTMEADLA----TQ  297
            + VFTTRPDTL G  Y  +APEH+L   +A + S+ A  + + K+ +++ +DLA    ++
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALV--DAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  298  EKKGFKTSIKVIHPISAETIDVWVANFVLMGYGSGAVMSVPAHDQRDWEFAQKYNIPLKQ  357
            EK G  T+   I+P+++  + VW+A++VL +YG+GA+M+VPAHD+RDWEFA+++N+ +  
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  358  VIESNDNKLKIDLEKQAFTEKGILINSGEFDGLNFKNAYQAIKKYLTKQNKGYETTNFRI  417
            V+E+       ++E  AFTE G+ INS+ +DGL+  +A   +   L  +  G E   +R+
Sbjct  361  VLEGG------NVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRL  414

Query  418  HDWGISRQRYWGCPIPMIHCDDCGAVPEKEENLPVRLPTDVALTEAG---SPLKDIPEFI  474
            +DW +SRQRYWG PIP+IH +D  + +  E +LP+ LP    +  +G   SPL ++ + +
Sbjct  415  RDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWL  474

Query  475  NVACPECGKPAKRETDTFDTFFESSWYYARYTCPTSNQMLDQEA--NYWLPVDKYIGGIE  532
            +V+  +  K ++RET+T      SSWYY RY  P + + L +E   + WLPVD Y+GG E
Sbjct  475  EVTREDGVK-GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAE  533

Query  533  HAIMHLLYARFFHKLMRDQGLVKSDEPFKNLLTQGMVL-------------------KDG  573
            HA++HLLYARF HK++ D G+V + EPF++L+ QGM+L                   +DG
Sbjct  534  HAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDG  593

Query  574  ---------------AKMSKSKGNIVDPQELIDKYGADTVRLFSMFAASPEQSLEWSETG  618
                           AKMSKS  N+V+P++++++YGADT+R++ MF ++ + S+ WSE G
Sbjct  594  SFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEG  653

Query  619  VEGANKFLRKVFNYAELNKVIFAKNITLESQKLTKEDKKARFEIHSNLKQAIFDFDKSQF  678
            +EG+ KFL +V+     + +   ++ +L+  K+ +E  KA   +  ++ Q  F+   +Q+
Sbjct  654  LEGSRKFLDRVYRLITTKEITEENSGALD--KVYNETVKA---VTEQVDQMKFNTAIAQL  708

Query  679  NTVVSACMKILNTLNNYDNLSESVKVEGFSILLRILAPFTPHLCHYLWQQLNL-GEDILH  737
               V+A  K  + +++Y +        GF   ++++APF+PHL + LWQ L   GE I  
Sbjct  709  MVFVNAANKEDKLFSDYAK--------GF---VQLIAPFAPHLGEELWQALTASGESISY  757

Query  738  TSFPTVDNNALEKDEFLLVVQINGKLKAKLELDASLSSNQVEEVVLADEHVKSFIDNKQV  797
             + P+ D++ L  ++  +VVQI+GK+KAKL +   LS ++++EV LA+E V++ I  K++
Sbjct  758  VPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDI  817

Query  798  VKVIYVPQKLINIVIK  813
            +KVI VP+KL+NIVIK
Sbjct  818  IKVIAVPNKLVNIVIK  833

1040) PCNPT3_03740 in NC_020802


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  549 bits (2072),  Expect = 3e-157, Method: Compositional matrix adjust.
 Identities = 367/863 (43%), Positives = 571/863 (67%), Gaps = 45/863 (5%)

Query  5    YDPKEIEAKFQQHWETQQSFKAVEDPSKEKYYCLSMFPYPSGK-LHMGHVRNYTIGDVVS  63
            YD   IE+K Q  W  +++FK+  D+SK K+Y L MFPYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMQGKNVMQPMGWDAFGLPAENAAIKNNTAPAGWTYENIAYMKKQLKQLGFGYDWTR  123
            R++R QG NV++PMGWDAFGLPAE+ A+     PA  T ENIA  K+Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EIATCKPEYYRWEQWFFTKLLEKDLVYKKMATVNWDPVDQTVLANEQVI-DGRGWRSGAL  182
            E+ T  P+YY+W QW+FTKL EK+L Y     VNW     T +ANE+V+ DG + R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VEQKEIPQWFIKITAYAQEllddldkldEWPEQVRTMQRNWIGRSEGVEMDFRVVGSDEK  242
            V +K + QW +KITAYA E L +     +WPE ++ MQRNWIG+S G ++ F+V ++D  
Sbjct  184  VVRKPMRQWMLKITAYA-ERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LSVYTTRPDTVMGVTYVAVAAQHP--laqqaaknnaalaDFCNKCK-NVKLAEAELATMP  299
            ++V+TTRPDT+ G TY  +A++H+   A  ++ +  A+AD+  +   +  LA ++LA   
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KEGVDTGLKAIHPITGKEVPIWTANFVLMGYGSGAVMSVPAHDQRDYEFAIQYGLDINAV  359
            K GV TG  AI+P+ GKE+P+W A++VL +YG+GA+M+VPAHD+RD EFA Q+ LDI +V
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  360  IKAADSDVDVSEKAYTDKGICFNSGEFDGLNFEEAFNAVEEKLSSENKGKRKVNFRLRDW  419
            + ++    +V E A+T+ G+ +NS+ +DGL+   A+  + E L +E  G+ +V +RLRDW
Sbjct  362  LEGG----NVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDW  417

Query  420  GVSRQRYWGTPIPTLTLEDGSIVPVPEDRLPVILP--EDVTMNGIT-SPIKADLEWAKTT  476
              SRQRYWG PIP +  EDG+  +VPE  LP++LP   D+  +G   SP+    +W   T
Sbjct  418  LFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT  477

Query  477  YKGQV-AYHETDTFDTFMESSWYYARYCSPQSDTQMLDPEKANYWLPVDQYIGGIEHAIL  535
              + V + +ET+T      SSWYY RY  P++  ++ D E  + WLPVD Y+GG EHA+L
Sbjct  478  REDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVL  537

Query  536  HLLYSRFFHKLLRDFGLVNSDEPFKKLLTQGMVLADAFYYEDEKGGKVWISPNDAITQTD  595
            HLLY+RF HK+L D+G+V + EPF+KL+ QGM+L+ +  Y D +G+   + + D + + D
Sbjct  538  HLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS--YRDSRGA---LVATDKVEKRD  592

Query  596  DKGKIISAKLENGQVLIFDGMCKMSKSKNNGIDPQIMIDKYGADSVRLFMMFAAPAEQTL  655
              G ++   +E G+ L  ++  KMSKS +N ++P+ ++++YGAD++R++ MF +P + ++
Sbjct  593  --GSFF--HVETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASI  647

Query  656  EWSDSALEGSLRFLKRLWKLANDHIELGSVDALDIKSQNDGQKALRRELHKTIKKVTDDI  715
             WS+ +LEGS +FL R+ +L         + + +I  +N G  AL +  + T+K VT+++
Sbjct  648  AWSEEGLEGSRKFLDRVYRL---------ITTKEITEENSG--ALDKVYNETVKAVTEQV  696

Query  716  GRRQTFNTAIASVMELMNKLLKAPTKNAQDRAILQEALVAVVKLLSPITPHICAELYELL  775
            ++ + FNTAIA +M ++N          ++  ++ +   + V+L++P++PH+  EL + L
Sbjct  697  DQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQAL  748

Query  776  GESDEILT-APWPCVDESALVEDSALIIVQVNGKLRAKLTVSKNASQESVETLALGHENI  834
              S+E ++  PWP  DES LVE+   I+VQ++GK++AKL V+K+ S+E ++ +AL++E++
Sbjct  749  TASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKV  808

Query  835  VKFTEGKNIRKIIFVPGKLLNIV  857
                 GK+I K+I VP KL+NIV
Sbjct  809  QAEIAGKDIIKVIAVPNKLVNIV  831

1041) Sros_7138 in NC_013595


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  549 bits (2071),  Expect = 3e-157, Method: Compositional matrix adjust.
 Identities = 359/852 (43%), Positives = 530/852 (63%), Gaps = 62/852 (7%)

Query  14   YDPQALQVKWQRRWEELDPFRASDDPADTRERRYMLDMFPYPSG-DLHMGHAEVFAIGDV  72
            YD  A++ KWQ  W + + F+++ D+  ++ + Y LDMFPYPSG +LH+GH+E ++  D+
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDA--SKPKFYALDMFPYPSGAGLHVGHPEGYTATDI  61

Query  73   VSRYWFQRGYNVLHPIGWDSFGLPAENAAIRRNAHPAEWTYANIETQAHSFKRYAVSFDW  132
            +SR+   +G NVLHP+GWD+FGLPAE+ A+    +PAE T  NI    + ++  + S+DW
Sbjct  62   LSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDW  121

Query  133  SRRLHTSDAEYYRWTQWLFIRFFERGLAYRKGGLVNWCPNDQTVLANEQV-KDGKCERCG  191
             R ++T+D++YY+WTQW+F +++E+GLAY     VNW  +  T +ANE+V  DG  ER G
Sbjct  122  DREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGG  181

Query  192  AEVVRRELTQWYFKITDYADRLLDDMAQLEGGWPERVLTMQRNWIGRSEGADVNFVIEGR  251
              VVR+ + QW +KIT YA+RLL+D+ +++  WPE +  MQRNWIG+S GA+V F + + 
Sbjct  182  YPVVRKPMRQWMLKITAYAERLLEDLEEVD--WPESIKDMQRNWIGKSTGANVTFKVKDT  239

Query  252  DEPVTVYTTRPDTLYGATFFVVAPDAALAEEIVTEDQREAFEAYRAEVSKLSDIDRLSTD  311
            D   TV+TTRPDTL+GAT+ V+AP+ AL + I T DQ EA   Y+ + S  SD+ R    
Sbjct  240  DKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA  299

Query  312  KEKTGVFLGRYAINPVNGERMPVWAADYVLSDYGHGAIMAVPAHDQRDLDFARTFGLPVR  371
            KEKTGV  G YAINPVNG  MPVW ADYVL+ YG GAIMAVPAHD+RD +FA+ F L + 
Sbjct  300  KEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDII  359

Query  372  VVVHTGLADPgetgvatagegaLVNSGPLDGLPKADAIRKIIGVLAERGTGRATVNFRLR  431
             V++ G  + +            +NS+ LDGL KA AI K++  L   G G   V +RLR
Sbjct  360  PVLEGGNVEEAAFTEDGLH----INSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  432  DWLLSRQRFWGCPIPIIHCADCGEVPVPDDQLPVTLPDLRGEALAPKGVSPLASADDWVN  491
            DWL+SRQR+WG PIPIIH  D    +VP+ +LP+ LP  ++   +  G SPLA+  DW++
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  492  VACPKCGGPARRDTDTMDTFVDSSWYFLRYVDPTYEDGPFDVEKLRQWGPIDQYVGGVEH  551
            V+    G  +RR+T+TM    +SSWY+LRY+DP   +   D E L+QW P+D YVGG EH
Sbjct  476  VTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEH  534

Query  552  AVLHLLYSRFFTKVLHDMGMVDFTEPFTRLLNQGQVINQG--------------------  591
            AVLHLLY+RF  KVL D+G+V   EPF +L+NQG ++  +                    
Sbjct  535  AVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGS  594

Query  592  --------------KAMSKSLGNGVDLGEQIDSYGVDAVRLTVVFAGPPEDDIDWADVSP  637
                            MSKSL N V+ ++ ++ YG D++R+  +F GP +  I W++ + 
Sbjct  595  FFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGL  654

Query  638  AASQKFLARAFRVMAEAGAASAPGVDFATGDLDLRKAVHRTIDEVTKLVDSHRFNVAVAR  697
             +S+KFL R +R+++    +        +G LD  K  + T+  VT  VD  +FN A+A+
Sbjct  655  EGSRKFLDRVYRLITTKEITEE-----NSGALD--KVYNETVKAVTEQVDQMKFNTAIAQ  707

Query  698  MMELTSATRKAIDSGPGAADPAVREAAETLAVMLSLVAPYTAEEGWERLGHPA-SVATAG  756
            +M + +A+ K         D    + A  +  +++  AP  +EE W+ L  ++ S++   
Sbjct  708  LMVFVNAANK--------EDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVP  759

Query  757  WPAAQAALLVQDSVTCVVQVAGKVRDRLEVSPEISDAELEVLALASEKVQSFLSG-APRK  815
            WP+ + + LV++ V  VVQ+ GKV+ +L V+ ++S  EL+ +ALA+EKVQ+ ++G    K
Sbjct  760  WPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIK  819

Query  816  VVVRAPKLVNIV  827
            V+  + KLVNIV
Sbjct  820  VIAVPNKLVNIV  831

1042) Tnap_0798 in NC_013642


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  549 bits (2073),  Expect = 3e-157, Method: Compositional matrix adjust.
 Identities = 361/840 (43%), Positives = 531/840 (64%), Gaps = 68/840 (8%)

Query  23   FYTPQRSEKPKYYALVMFPYPSGT-LHVGHVKNYVIGDIVARYKRMRGYNVLHPFGYDAF  81
            F T   + KPK+YAL MFPYPSG+ LHVGH   Y   DI++R+KR +G NVLHP G DAF
Sbjct  23   FKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSRFKRAQGHNVLHPMGWDAF  82

Query  82   GLPAENAAIEKGIHPEEWTRKNINTIRGQVKKLGISYDWSREIATCDEEYYKWTQWIFLQ  141
            GLPAE+ A++ G +P E T  NI  ++ Q++ LG+SYDW RE+ T D +YYKWTQWIF +
Sbjct  83   GLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTK  142

Query  142  LYKNGLAYKKKAAVNWCPKCKTVLANEQV-KDGKCERCGTSVTIRHLEQWFFKITDYAER  200
            LY +GLAY    +VNW     T +ANE+V  DG  ER G +V  + + QW +KIT YAER
Sbjct  143  LYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAER  202

Query  201  LLNDLDKLTGWPEHVKTMQRNWIGKSTGAEIDFPVEGSDTKIRVFTTRPDTLWGVTFMal  260
            LL+DL+ + +WPE +K MQRNWIGKSTGA++ F V ++D  + VFTTRPDTL G T+  L
Sbjct  203  LLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVL  261

Query  261  apesplveelvleekkedlqeFLERVKQQDRFRRTSVEAEKEGFFLGRYAINPVTGERIP  320
            APE +LV+ +   ++ E + ++  +   +  + RT +  EK G   G YAINPV G  +P
Sbjct  262  APEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAINPVNGKEMP  321

Query  321  IYVANYILMEYGTGAIMGVPAHDQRDFSFAKKYGIPIKVVIKPADRDLDPEKMEEAYEGE  380
            + +A+Y+L  YGTGAIM+VPAHD+RD  FAK++ + I  V+  ++ +      E A+  +
Sbjct  322  VWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVE------EAAFTED  375

Query  381  GIMVNSGPFDGTPSSEGIEKVINWLEEKGIGKRSVQYKLRDWLISRQRYWGAPIPIIYCE  440
            G+ +NS+ +DG   + +I K+++WLE  G+G+ +V Y+LRDWL+SRQRYWG PIPII  E
Sbjct  376  GLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWE  435

Query  441  KCGVVPVPEEDLPVRLPKDVEFLPTGQSPLSFHEGFKRTKCPICGG-EAQRETDTMDTFV  499
                 +VPE +LP+ LP   ++ P+G +  ++ +   +      +G  ++RET+TM    
Sbjct  436  DGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVKGRRETNTMPQWA  495

Query  500  DSSWYFLRYVNPHLEDKPFEPDDVNYWLPVDQYIGGVEHAVLHLLYSRFVTKVLHDLGYL  559
            +SSWY+LRY++PH  +K  + + ++ WLPVD Y+GG EHAVLHLLY+RF  KVL DLG +
Sbjct  496  GSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVV  555

Query  560  NFDEPFTNLFTQGMI----YKDG------------------------------AKMSKSK  585
               EPF +LF QGMI    Y+D+                              AKMSKS 
Sbjct  556  PTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSL  615

Query  586  GNVVSPDEMIEKYGADTLRMYILFMAPPEKDAEWSDAGIEGVHRFVKRLWNTFYTVLPFV  645
             NVV+PD+++E+YGADTLR+Y +FM+P +    WS+ G+EG ++F+ R+    Y ++   
Sbjct  616  KNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRV----YRLIT-T  670

Query  646  KEENTENLVLKNSTEKELRRKLHSIIKKITEDIEGGFKFNTAISGLMELVNHLSQYLNSV  705
            KE       + +     L +  +  +K +TE+++   KFNTAI+ LM        ++N+ 
Sbjct  671  KE-------ITEENSGALDKVYNETVKAVTEQVD-QMKFNTAIAQLM-------VFVNAA  715

Query  706  PQEEWNRKLLREIVEKLTLALSPFAPHLAEEFWHDLGNENLVVQ-QSWPSYDPKALQVEE  764
             +E+   KL+ +    +   ++PFAPHL+EE+W+ L      +   +WPSYD   L  ++
Sbjct  716  NKED---KLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVEND  772

Query  765  VEIAIQINGKVRDKVVVPVDISEEDLKKIVLERERVKEYVDGKPIKKFLYVRGRIVNIVV  824
            VEI +QI+GKV+ K+VV+ D+S E+L+ + L  E+V+  + GK I K + V  ++VNIV+
Sbjct  773  VEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

1043) leuS in NC_002936


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  549 bits (2073),  Expect = 3e-157, Method: Compositional matrix adjust.
 Identities = 355/849 (42%), Positives = 539/849 (64%), Gaps = 59/849 (6%)

Query  5    YNPQETEKKWQDKWAADRLYHAGEDSPKPKWYSLTMFPYTSG-NLHIGHWYAEVPADCFA  63
            Y+    E KWQ  WA ++ + +G D++KPK Y+L MFPY SG  LH+GH  +  ++D ++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYKRLNGFNVMRPVGFDSFGLPAENAAIKHHIHPRIWTLNNVENMRRQLKTIGAMFDWDR  123
            R+KR +G NV++P+G D+FGLPAE+ A+    +P   T +N+ N +RQ++++G  +DWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVITCLPEYYKWTQWFFLKLYEAGLAYRAKAPVNWCPSCQAVLANEQVV-DGTCWRCETP  182
            EV T  P+YYKWTQW+F KLYE GLAY A  PVNW     + +ANE+V+ DGT  R   P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  TTRRDLEQWFFRITNYADEL-KDHDGLDWPEKITAMQRNWVGKSYGAEVSFALDCPAAPE  241
              R+ + QW ++IT YA+ L  D + +DWPE I  MQRNW+GKS GA+V+F +      +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVK---DTD  240

Query  242  QEIKVFTTRPDTIYGVTFMVLAPEHPLVEKITTPENKAAVDEYIKKSRACTEIERLSTER  301
            +++ VFTTRPDT++G T+ VLAPEH+LV+ ITT+++  AV +Y +++   +++ R    +
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  302  EKDGVFTGAYVTNRVNGHKVPVWIGDYVLQSYGTGAVMGVPAHDERDFVFAQKYDLPVIT  361
            EK GV TG+Y  N VNG  +PVWI+DYVL SYGTGA+M+VPAHDERD  FA++++L +I 
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  362  VIAPPDYDGQPLEAAYINEGVMQNSGPFNGLPNTEGKEKVCDYLAEHGWGKKTVNYKLRD  421
            V+     +G+  EAA+ ++G+  NS+ ++GL ++ +  K+ + L  +G G+  V Y+LRD
Sbjct  361  VLE----GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  422  WLISRQRYWGAPIPMIYCEKCGIVPVPEKDLPVLLPEDVEFRSG--GESPLKYNEGFVNT  479
            WL+SRQRYWG PIP+I  E     +VPE +LP++LP   ++R++  GESPL    + ++ 
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  480  TCPVCGGKAKRETDTMDTFMCSSWYFLRYTSPGYDKGPFDPEKLRYWMPVDLYTGGAEHA  539
            T    G K++RET+TM     SSWY+LRY  P       D E L+ W+PVD+Y GGAEHA
Sbjct  477  TRE-DGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  540  VMHLFYSRFFTKALRDMGIIDFGEPFKKLFNQGIIVSN----------------------  577
            V+HL+Y+RF  K L D+G++   EPF+KLFNQG+I++                       
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSF  595

Query  578  ------------HQKMSKSKGNVVTPDNLVAEVGTDAVRAYLMFVGPWDQGGEWNDSGLS  625
                          KMSKS  NVV PD++V + G+D++R Y MF+GP D +  W++ GL 
Sbjct  596  FHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLE  655

Query  626  GMSRWLNRVWNLFTEEYTPQTASAEAERELKRTLHQTIKKITMDIERLRFNTVVAALMEL  685
            G  + L+RV  L+    T +  + E    L +  ++T+K +T ++++++FNT +A LM  
Sbjct  656  GSRKFLDRVYRLI----TTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMV-  710

Query  686  SNSLAKFKEAAAVSAESWQNSLKTFALMLAPVAPHIAEELWANL-DMEYSIHNQSWPKWD  744
                  F +AA        +  K F  ++AP APH++EELW  L     SI   +WP  D
Sbjct  711  ------FVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYD  764

Query  745  EELAKDEVITLIIQVNGKLRERLEMPAGISEDEAKETALNSTRVKPHLQGKTPASVIYVP  804
            E    ++ + +++Q++GK++ +L ++ ++S +E +E AL + +V++++ GK    VI VP
Sbjct  765  ESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVP  824

Query  805  GKLVNIVVK  813
             KLVNIV+K
Sbjct  825  NKLVNIVIK  833

1044) FNFX1_0882 in NC_017450


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  549 bits (2073),  Expect = 3e-157, Method: Compositional matrix adjust.
 Identities = 354/856 (42%), Positives = 549/856 (65%), Gaps = 72/856 (8%)

Query  4    YNFSDIEKSTQVYWRKNDTFKTIEDNTKEKFYCLSMLPYPSGT-LHMGHVRNYTIGDVIA  62
            Y+ + IE   Q +W  N+TFKT  D +K KFY L M+PYPSG+ LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYQKMQGKNVLHPMGWDAFGLPAENAAIKHKKSPYEWTKSNIAYMRSQLDSLGFSFDWSR  122
            R+++ QG NVLHPMGWDAFGLPAE+ A+   + P E T  NIA  + Q+++LGFS+DW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EIATCDEDYYKWEQWFFIQLYKKGLAYRKNSVVNW-DPVDQTVLANEQVVDGRGWRSGAL  181
            E+ T D +YYKW QW+F +LY KGLAY  +  VNW + ++ ++  +E + DG + R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VEKKEIPQWFLKITDYADELLQDISKLDGWPEAVKTMQINWIGKSKGLTVKFKIKDSNQE  241
            V +K + QW LKIT YA+ LL+D+  +D WPE++K MQ NWIGKS G  V FK+KD++++
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  242  IEVFTTRPDTLMGVNYLGIAPEHPLALEEAKTNSKLAAFIEECKKTSTMEADLA----TQ  297
            + VFTTRPDTL G  Y  +APEH+L   +A T S  A  + + K+ +++ +DLA    ++
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALV--DAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  298  EKKGFKTSIKVIHPISGETIDVWVANFVLMGYGSGAVMSVPAHDQRDWEFAQKYDIPLKQ  357
            EK G  T+   I+P++G  + VW+A++VL +YG+GA+M+VPAHD+RDWEFA+++++ +  
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  358  VIESNDNKLKIDLEKQAFTEKGILINSGEFDGLNFKNAYQAIKKYLTEQNKGYETTNFRI  417
            V+E+       ++E  AFTE G+ INS+ +DGL+  +A   +   L  +  G E   +R+
Sbjct  361  VLEGG------NVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRL  414

Query  418  HDWGISRQRYWGCPIPMIHCDDCGAVPEKEENLPVRLPTDVTLTEAG---SPLKDIPEFI  474
            +DW +SRQRYWG PIP+IH +D  + +  E +LP+ LP    +  +G   SPL ++ + +
Sbjct  415  RDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWL  474

Query  475  NVACPECGKPAKRETDTFDTFFESSWYYARYTCPTANQMLDQEA--NYWLPVDKYIGGIE  532
            +V+  +  K ++RET+T      SSWYY RY  P   + L +E   + WLPVD Y+GG E
Sbjct  475  EVTREDGVK-GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAE  533

Query  533  HAIMHLLYARFFHKLMRDQGLVKSDEPFKNLLTQGMVL-------------------KDG  573
            HA++HLLYARF HK++ D G+V + EPF++L+ QGM+L                   +DG
Sbjct  534  HAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDG  593

Query  574  ---------------AKMSKSKGNIVDPQELIDKYGADTVRLFSMFAAPPEQSLEWSETG  618
                           AKMSKS  N+V+P++++++YGADT+R++ MF +P + S+ WSE G
Sbjct  594  SFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEG  653

Query  619  VEGANKFLRKVFNYAELNKDIFAKNITLESQKLTKEDKKARFEIHSNLKQAIFDFDKSQF  678
            +EG+ KFL +V+     +     ++ +L+  K+ +E  KA   +  ++ Q  F+   +Q+
Sbjct  654  LEGSRKFLDRVYRLITTKEITEENSGALD--KVYNETVKA---VTEQVDQMKFNTAIAQL  708

Query  679  NTVVSACMKILNTLNNYNNLSESVKIEGFSILLRILAPFTPHLCHYLWQQLNL-GEDILH  737
               V+A  K  + +++Y +        GF   ++++APF+PHL + LWQ L   GE I  
Sbjct  709  MVFVNAANKEDKLFSDYAK--------GF---VQLIAPFAPHLGEELWQALTASGESISY  757

Query  738  TSFPTVDNNALEKDEFLLVVQINGKLKAKLELDASLSPNQVEEIVLADEHVKSFIDNKQV  797
             + P+ D++ L  ++  +VVQI+GK+KAKL +   LS ++++E+ LA+E V++ I  K++
Sbjct  758  VPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDI  817

Query  798  VKVIYVPQKLINIVIK  813
            +KVI VP+KL+NIVIK
Sbjct  818  IKVIAVPNKLVNIVIK  833

1045) leuS in NC_021064


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  549 bits (2072),  Expect = 3e-157, Method: Compositional matrix adjust.
 Identities = 351/855 (42%), Positives = 535/855 (63%), Gaps = 64/855 (7%)

Query  11   YDAAAAQEKWSRYWEENRTFAALDDGSKERRYVLDMFAYPSG-DLHMGHAEAFAIGDVLA  69
            YD +A + KW  +W +N+TF +  D+SK + Y LDMF+YPSG +LH+GH+E+++  D+L+
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  70   RYWRLRGFDVLHPVGWDSFGLPAENAAIKHGTHPAEWTYNNIDTQAASFKRYAVSFDWSM  129
            R+ R +G +VLHP+GWD+FGLPAE+ A+  G +PAE T +NI      ++  + S+DW  
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  130  RLHTSDEEYYRWTQWLFNRFFEKGLAYRKDSWANWCPNDQTVLANEQV-KDGCCERCGAV  188
             ++T+D +YY+WTQW+F +++EKGLAY  +   NW  +  T +ANE+V  DG  ER G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  189  VTKRQLNQWYFRITDYAQRLLDDMGQIEGKWPDRVLSMQRNWIGRSEGAYVDFTIDGREE  248
            V ++ + QW ++IT YA+RLL+D+ +++  WP+ +  MQRNWIG+S GA V F + + + 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD--WPESIKDMQRNWIGKSTGANVTFKVKDTDK  241

Query  249  PVRVFTTRADTLYGATFMVVAPDSALAQEIVSDEARPDFEAYLGEVKKKSEIERQSTEYE  308
               VFTTR+DTL+GAT+ V+AP+ AL + I + +       Y  +   KS++ R     E
Sbjct  242  DFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKE  301

Query  309  KTGVPLGVEATNPVNGAKIPVWAGDYVLADYGTGAVMAVPAHDQRDLDFARKYGIDVIPV  368
            KTGV  G  A NPVNG  +PVW +DYVLA YGTGA+MAVPAHD+RD +FA+++ +D+IPV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  369  IDTGEADPRESGIATTGDGAYQNSGFLDGITTKAEAIEKMCEFLGDKGIGESTITYRLRD  428
            ++ G+ +      A T DG   NS+FLDG+  KA AI KM E L   G+G+  +TYRLRD
Sbjct  362  LEGGNVE----EAAFTEDGLHINSDFLDGL-DKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  429  WLLSRQRFWGCPIPIIHCDTCGDVPVPDDQLPVKLPDLRGAELAPKGKSPLAGEEAREWR  488
            WL+SRQR+WG PIPIIH +     +VP+ +LP+ LP  ++   +  G SPLA  +  +W 
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLA--NVTDWL  474

Query  489  KVSCPRCGEAAQRDTDTMDTFVDSSWYFMRYCSPHFDQGPFDTDAVRRWMPVAQYIGGVE  548
             V+    G  ++R+T+TM    +SSWY++RY  PH  +   D + +++W+PV  Y+GG E
Sbjct  475  EVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAE  533

Query  549  HATMHLLYSRFFTKVLHDLGMVDFTEPFQRLMNQGQVIN----EGRA-------------  591
            HA +HLLY+RF  KVL DLG+V   EPFQ+L NQG ++     ++R+             
Sbjct  534  HAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDG  593

Query  592  -----------------MSKSLGNGVDLGKQIDEFGVDAVRTTVIFAGPPDEDIDWADVS  634
                             MSKSL N V+ +  ++++G D++R   +F GP D  I W++ +
Sbjct  594  SFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEG  653

Query  635  PASILKFLQRAWRV--ASEVTSDPDVDVTKGDGGLRRVTHRSIADITELLDGGRYNVVVA  692
              +  KFL+R  R+  + E+T +         G+L +V + ++  +TE +D  ++N  +A
Sbjct  654  LEGSRKFLDRVYRLITTKEITEE-------NSGALDKVYNETVKAVTEQVDQMKFNTAIA  706

Query  693  RIMELVNATRKAIDAGCGPADPAVREAVTFTAQALSLVAPYLAEEMWEML-GLEPSVANS  751
            ++M +VNA+ K      + A   V+    F        AP L+EE+W+ L +   S++  
Sbjct  707  QLMVFVNAANKEDKLFSDYAKGFVQLIAPF--------APHLGEELWQALTASGESISYV  758

Query  752  QWPTADEKLLVAEEVTMVVQVTGKVRAKIQVSPDITEEEARELALADSNVQRFTEGKEII  811
             WP+ DE  LV ++V +VVQ+ GKV+AK+ V+ D++ EE +E+ALA+ +VQ    GK+II
Sbjct  759  PWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDII  818

Query  812  KVIARLPKMISIVAK  826
            KVIA   K+++IV K
Sbjct  819  KVIAVPNKLVNIVIK  833

1046) leuS in NC_009655


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  549 bits (2073),  Expect = 3e-157, Method: Compositional matrix adjust.
 Identities = 354/866 (41%), Positives = 567/866 (66%), Gaps = 46/866 (5%)

Query  5    YRPDLIEAEVQKYWQENKTFKAIKDTNKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVVS  63
            Y    IE+  Q +W +N TFK+  D++K K+Y L M+PYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMIGKNVLQPMGWDAFGLPAEGAAVKNNTAPAKWTYENIEYMKNQLKVLGFSYDWER  123
            R++R  G NVL+PMGWDAFGLPAE  A+     PA  T ENI   K Q++ LGFSYDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVTTCRPEYYKWEQWFFTELYKKGLVYKKTSVVNWCPNDETVLANEQV-HEGCCWRCDTP  182
            EV T  P+YYKW QW+FT LY KGL Y     VNW  +  T +ANE+V  +G   R + P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VEQREIPQWFIKITDYAEQLLGGLDTLPEWPEMVKTMQRNWIGRSEGVEITFKIENSDET  242
            V ++ + QW +KIT YAE+LL +L+ + +WPE +K MQRNWIG+S G ++TFK+ ++D  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  VAVYTTRPDTFYGVSYMAVAAGHPLAE--RAAQNNPDLAKFIQECK-NTKVAEAELATME  299
             +V+TTRPDT++G +Y  +A+ H+L +   ++++   +A + ++   ++ +A ++LA  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGMATGLNAVHPITGKPVPIWVANFVLMHYGTGAVMAVPAHDQRDFEFATKYDLPINQV  359
            K G+ TG  A++P+ GK +P+W+A++VL  YGTGA+MAVPAHD+RD EFA +++L   ++
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNL---DI  358

Query  360  IAPVNGEDIDLSKAAFTEHGKLVNSAEFDGLDFDAAFNGIADKLERMGAGKRQVNYRLRD  419
            I+ ++G +++   AAFTE+G  +NS  +DGLD  +A+  + + LE  G G+ +V YRLRD
Sbjct  359  IPVLEGGNVE--EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMLTLENGDVVPAPLQDLPIVLP--EDVVMDGV-KSPIKADPDWAKT  476
            W  SRQRYWG PIP++  E+G   + P  +LP+VLP   D+   G   SP+    DW   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  TY-NGRPALKETDTFDTFMESSWYYARYTCPQYHEGMLDSEEANYWLPVDQYIGGIEHAT  535
            T  +G  + +ET+T      SSWYY RY  P+  E + D E  + WLPVD Y+GG EHA 
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLLYFRFFHKLLRDAGLVSTDEPTKKLLCQGMVLADAFYYTSPTNERIWVSPTKVTLER  595
            +HLLY RF HK+L D G+V+T EP +KL+ QGM+L+ ++      + R     + V+ ++
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSR----GALVATDK  587

Query  596  DEKGRIVKALDDEGRELVHAGMTKMSKSKNNGIDPQEMVEKYGADTVRLFMMFASPAEMT  655
             EK R    ++ E  E ++ + +KMSKS +N ++P+++VE+YGADT+R++ MF +P + +
Sbjct  588  VEK-RDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  656  LEWQESGVEGAKRFLGRLWNLVFEYNKNPAKTALNPTALSGVQKALRRGVHKTIAKVSDD  715
            + W E G+EG+++FL+R+      Y    +K   +  +      AL +  + T+  V+++
Sbjct  647  IAWSEEGLEGSRKFLDRV------YRLITTKEITEENS-----GALDKVYNETVKAVTEQ  695

Query  716  IGRRQTFNTAIAAIMELMNKLTRASLAGEQDRAIMGEALSAVVRMLYPITPHVCFQLWKE  775
            +++ + FNTAIA +M ++N       A++++  + ++   + V+++ P++PH+  +LW+ 
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  776  L-GNEDVIDFAPWVQADEAAMVEEEKLVVVQVNGKVRGKITVPADMAEDDIKQAALADEN  834
            L ++ + I + PW   DE+ +VE++  +VVQ++GKV++K+ V+ D++ +++++ ALA+E+
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  835  VQKFLSGLNIVKTIYVPGKLFSFVAK  860
            VQ  ++G +I+K I VP KL ++V K
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVIK  833

1047) leuS in NC_009486


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  549 bits (2071),  Expect = 4e-157, Method: Compositional matrix adjust.
 Identities = 362/840 (44%), Positives = 531/840 (64%), Gaps = 68/840 (8%)

Query  23   FYTPQRSEKPKYYALVMFPYPSGT-LHVGHVKNYVIGDIVARYKRMRGYNVLHPFGYDAF  81
            F T   + KPK+YAL MFPYPSG+ LHVGH   Y   DI++R+KR +G NVLHP G DAF
Sbjct  23   FKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSRFKRAQGHNVLHPMGWDAF  82

Query  82   GLPAENAAIEKGIHPEEWTRKNINTIRGQVKKLGISYDWSREIATCDEEYYKWTQWIFLQ  141
            GLPAE+ A++ G +P E T  NI  ++ Q++ LG+SYDW RE+ T D +YYKWTQWIF +
Sbjct  83   GLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTK  142

Query  142  LYKNGLAYKKKAAVNWCPKCKTVLANEQV-KDGKCERCGTSVTIRHLEQWFFKITDYAER  200
            LY +GLAY    +VNW     T +ANE+V  DG  ER G +V  + + QW +KIT YAER
Sbjct  143  LYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAER  202

Query  201  LLNDLDKLTGWPEHVKTMQRNWIGKSTGAEIDFPVEGSDTKIRVFTTRPDTLWGVTFMal  260
            LL+DL+ + +WPE +K MQRNWIGKSTGA++ F V ++D  + VFTTRPDTL G T+  L
Sbjct  203  LLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVL  261

Query  261  apesplveelvleekkedlqeFLERVKQQDRFRRTSVEAEKEGFFLGRYAINPVTGERIP  320
            APE +LV+ +   ++ E + ++  +   +  + RT +  EK G   G YAINPV G  +P
Sbjct  262  APEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAINPVNGKEMP  321

Query  321  IYVANYILMEYGTGAIMGVPAHDQRDFSFAKKYGIPIKVVIKPADRDLDPEKMEEAYEGE  380
            + +A+Y+L  YGTGAIM+VPAHD+RD  FAK++ + I  V+  ++ +      E A+  +
Sbjct  322  VWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVE------EAAFTED  375

Query  381  GIMVNSGPFDGTPSSEGIEKVINWLEEKGIGKRSVQYKLRDWLISRQRYWGAPIPIIYCE  440
            G+ +NS+ +DG   + +I K+++WLE  G+G+ +V Y+LRDWL+SRQRYWG PIPII  E
Sbjct  376  GLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWE  435

Query  441  KCGVVPVPEEDLPVRLPKDVEFLPTGQSPLSFHEGFKRTKCPICGG-EAQRETDTMDTFV  499
                 +VPE +LP+ LP   ++ P+G +  ++ +   +      +G  ++RET+TM    
Sbjct  436  DGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVKGRRETNTMPQWA  495

Query  500  DSSWYFLRYVNPHLEDKPFEPDDVNYWLPVDQYIGGVEHAVLHLLYSRFVTKVLHDLGYL  559
            +SSWY+LRY++PH  +K  + + ++ WLPVD Y+GG EHAVLHLLY+RF  KVL DLG +
Sbjct  496  GSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVV  555

Query  560  NFDEPFTNLFTQGMI----YKDG------------------------------AKMSKSK  585
               EPF +LF QGMI    Y+D+                              AKMSKS 
Sbjct  556  PTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSL  615

Query  586  GNVVSPDEMIEKYGADTLRMYILFMAPPEKDAEWSDAGIEGVHRFIKRLWNTFYTVLPFV  645
             NVV+PD+++E+YGADTLR+Y +FM+P +    WS+ G+EG ++F+ R+    Y ++   
Sbjct  616  KNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRV----YRLIT-T  670

Query  646  KEENTENLVLKNSTEKELRRKLHSIIKKITEDIEGGFKFNTAISGLMELVNHLSQYLNSV  705
            KE       + +     L +  +  +K +TE+++   KFNTAI+ LM        ++N+ 
Sbjct  671  KE-------ITEENSGALDKVYNETVKAVTEQVD-QMKFNTAIAQLM-------VFVNAA  715

Query  706  PQEEWNRKLLREIVEKLTLALSPFAPHLAEEFWHDLGNDSLVVQ-QAWPSYDPKALEVEE  764
             +E+   KL+ +    +   ++PFAPHL+EE+W+ L   +  +   +WPSYD   L  ++
Sbjct  716  NKED---KLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVEND  772

Query  765  VEIAIQINGKVRDKVVVPVDISEEALKRIVLERERVKEYVDGKPIRKFIYVKGRIVNIVV  824
            VEI +QI+GKV+ K+VV+ D+S E L+ + L  E+V+  + GK I K I V  ++VNIV+
Sbjct  773  VEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

1048) leuS in NC_004547


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  549 bits (2071),  Expect = 4e-157, Method: Compositional matrix adjust.
 Identities = 355/876 (41%), Positives = 551/876 (63%), Gaps = 68/876 (7%)

Query  5    YRPEEIEADVQLHWQEKQTFKVTEQLGKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIS  63
            Y    IE+  Q  W +++TFK   + +K K+Y L M+PYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYANIDYMKNQLKLLGFGYDWDR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T  NI   K Q++ LGF+YDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EIATCKPDYYRWEQWFFTKLYEKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W QW+FTKLYEKGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADQLLNDLDTLESWPEQVKTMQRNWIGRSEGVEITFDVADSEEK  242
            V RK + QW +KITAYA++LL+DL+ ++ WPE +K MQRNWIG+S G ++TF V D++  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LSVYTTRPDTFMGVTYVAVAAGHPLAAQAAVTNPALADFIAECRNTKVAEADMA----TM  298
            ++V+TTRPDT+ G TY  +A+ H+L    A+T +  A+ +A+ +      +D+A    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALV--DAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  299  EKKGMATGLYAIHPLNGEKVAIWVANFVLMEYGTGAVMAVPGHDQRDWEFATKYDLSIKP  358
            EK G+ TG YAI+P+NG  +++W+A++VL  YGTGA+MAVP+HD+RDWEFA +++L I P
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VILNADGSEPDLSAQAMTEKGSLFNSGEFDGLDFEAGFNAIADKLVEKGIGERKVNYRLR  418
            V+  ++  E+ ++ +++  ++ +     +DGLD  +++  + + L   G+G+ +V YRLR
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDF-----LDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  419  DWGVSRQRYWGAPIPMMTLEDGTVIPTPEDQLPVILP--EDVVMDGIT-SPLKSNPEWAK  475
            DW  SRQRYWG PIP++  EDGT  + PE +LP++LP   D+   G   SPL +  +W  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  476  TT-VNGQPALRETDTFDTFMESSWYYARYTCPQYDQGMLDPAAANYWLPVDQYVGGIEHA  534
             T  +G  + RET+T      SSWYY RY  P+  + + D    + WLPVD YVGG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  535  IMHLMYFRFFHKLMRDAGLVTSDEPAKRLLCQGMVLADAFYYLGNNGERIWVSPTDVTVE  594
            ++HL+Y RF HK++ D G+V + EP ++L+ QGM+L+ ++                    
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY--------------------  575

Query  595  RDEKGRIVKATDNEGRDVVY----------AGMSKMSKSKNNGIDPQIMVEKYGADTVRL  644
            RD +G +V +   E RD  +           + +KMSKS +N ++P+ +VE+YGADT+R+
Sbjct  576  RDSRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRV  635

Query  645  FMMFASPAEMTLEWQESGVEGANRFLKRVWRQAFEHTGKGAVTALDITTLTEDQKSLRRD  704
            + MF +P + ++ W E G+EG+ +FL RV R          +T+ +IT   E+  +L + 
Sbjct  636  YEMFMGPLDASIAWSEEGLEGSRKFLDRVYR---------LITTKEIT--EENSGALDKV  684

Query  705  LHKTIAKVTDDIGRRQTFNTAIAAIMELMNKLAKAPQESDQDRALTQETLLAVVRMLYPF  764
             + T+  VT+++++ + FNTAIA +M ++N        ++++  L  +   + V+++ PF
Sbjct  685  YNETVKAVTEQVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPF  736

Query  765  TPHVCFTLWQALQGEGD-VDTAPWPVADENAMVEDSKLVVVQVNGKVRGKITVAADASEE  823
            +PH+   LWQAL + G+ +   PWP  DE+ +VE+   +VVQ++GKV++K+ VA D S E
Sbjct  737  APHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSRE  796

Query  824  QVRERAAQEPLVAKYLDGVTVRKVIYVPGKLLNLVV  859
            +++E A  +  V   + G  + KVI VP KL+N+V+
Sbjct  797  ELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

1049) leuS in NC_020387


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  548 bits (2069),  Expect = 5e-157, Method: Compositional matrix adjust.
 Identities = 350/849 (42%), Positives = 539/849 (64%), Gaps = 59/849 (6%)

Query  5    YNPQETEKKWQDKWAADRLYHASEDSPKPKWYSLTMFPYTSG-NLHIGHWYAEVPADCFA  63
            Y+    E KWQ  WA ++ + ++ D++KPK Y+L MFPY SG  LH+GH  +  ++D ++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYKRLRGFNVMRPVGFDSFGLPAENAAIKHNIHPRIWTLNNVENMRRQLKTIGAMFDWDR  123
            R+KR +G NV++P+G D+FGLPAE+ A+    +P   T +N+ N +RQ++++G  +DWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVITCLPEYYKWTQWFFLKLYEAGLAYRAKAPVNWCPSCQAVLANEQVV-DGTCWRCETP  182
            EV T  P+YYKWTQW+F KLYE GLAY A  PVNW     + +ANE+V+ DGT  R   P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  TTRRDLEQWFFRITNYADEL-KDHEGLDWPEKITAMQRNWVGKSYGAEVSFALDCPTAFE  241
              R+ + QW ++IT YA+ L  D E +DWPE I  MQRNW+GKS GA+V+F +      +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDT---D  240

Query  242  KEIKVFTTRPDTIYGVTFMVLAPEHPLVEKITTPENKAAVDAYIKKSRTCTEIERLSTER  301
            K++ VFTTRPDT++G T+ VLAPEH+LV+ ITT+++  AV  Y +++   +++ R    +
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  302  EKDGVFTGTYVTNRVNGQKVPVWIGDYVLQSYGTGAVMGVPAHDERDFVFAQKYHLPVIT  361
            EK GV TG+Y  N VNG+ +PVWI+DYVL SYGTGA+M+VPAHDERD  FA++++L +I 
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  362  VIAPSAYDDKPLEVAYINEGVMLNSGPFNGMPNTEGKEKVCDYLAEHGWGKKTVNYKLRD  421
            V+  +  +    E A+ ++G+ +NS+ ++G+ ++ +  K+ + L  +G G+  V Y+LRD
Sbjct  361  VLEGGNVE----EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  422  WLISRQRYWGAPIPMVYCEKCGIVPIPEKDLPVLLPEDVEFRSG--GESPLKYNEGFVNT  479
            WL+SRQRYWG PIP++  E     ++PE +LP++LP   ++R++  GESPL    + ++ 
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE-  475

Query  480  ICPVCGGKAKRETDTMDTFMCSSWYFLRYTSPGYDKGPFDPVKLKYWMPVDLYTGGAEHA  539
            +    G K++RET+TM     SSWY+LRY  P       D   LK W+PVD+Y GGAEHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  540  VMHLFYSRFFTKALRDMGIIDFGEPFKKLFNQGIIVSN----------------------  577
            V+HL+Y+RF  K L D+G++   EPF+KLFNQG+I++                       
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSF  595

Query  578  ------------HQKMSKSKGNVVTPDNLVAEVGTDAVRAYLMFVGPWDQGGEWNDSGLS  625
                          KMSKS  NVV PD++V + G+D++R Y MF+GP D +  W++ GL 
Sbjct  596  FHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLE  655

Query  626  GLSRWLNRVWNLFTEEYTPKTASAEAERELERTLHQTIKKITMDIERLRFNTVVAALMEL  685
            G  + L+RV  L+    T K  + E    L++  ++T+K +T ++++++FNT +A LM +
Sbjct  656  GSRKFLDRVYRLI----TTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVF  711

Query  686  SNSLAKLKETAAISAENWQNTLQTFALMLAPVAPHIAEELWANLGMK-YSIHNQNWPTWD  744
             N+  K             +  + F  ++AP APH++EELW  L     SI    WP+ D
Sbjct  712  VNAANK-------EDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYD  764

Query  745  EELAKDEVITLIIQVNGKLRERLEMPAGISEAEAKETALNSERVKPHLLGKTPVTVIYVP  804
            E    ++ + +++Q++GK++ +L ++ ++S  E +E AL +E+V++++ GK  + VI VP
Sbjct  765  ESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVP  824

Query  805  GKLVNIVVK  813
             KLVNIV+K
Sbjct  825  NKLVNIVIK  833

1050) Dbac_0057 in NC_013173


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  548 bits (2069),  Expect = 5e-157, Method: Compositional matrix adjust.
 Identities = 356/868 (42%), Positives = 546/868 (63%), Gaps = 74/868 (8%)

Query  1    MRHYDFKQIEEKWQQAWEEKACFRTDMSRDGEKYYVLEMFPYPSGR-IHMGHVRNYSIGD  59
            M  YD   IE KWQ  W ++  F+T+      K+Y L+MFPYPSG  +H+GH   Y+  D
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  60   VVARYKRMQGFNVFHPMGWDAFGLPAENAAIKNNTHPAKWTYENIAYMRAQLKRLGYSYD  119
            +++R+KR QG NV+HPMGWDAFGLPAE+ A+    +PA  T ENIA  + Q++ LG+SYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  120  WDREIATCHPGYYRfeqefflkflekGLVYRKNAPVNWCPSCHTVLANEQV-EEGLCWRC  178
            WDRE+ T +P YY+  Q +F K+ EKGL Y  + PVNW     T +ANE+V  +G   R 
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  179  DSEVQQKQLSQWFLRITDYAEELLADLDKLTDGWPERVLTMQRNWIGKSIGAEISFKVKD  238
            +  V +K + QW L+IT YAE LL DL+ +  +WPE +  MQRNWIGKS GA+++FKVKD
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEV--DWPESIKDMQRNWIGKSTGANVTFKVKD  238

Query  239  LDEAIPVFTTRPDTLFGATFMSLAPEHPLVEKLVAGTAQEAAVGEFVDRIAKMDRIVRTA  298
             D  + VFTTRPDTLFGAT+  LAPEH+LV+  ++ + Q  AV+++  + +    + RT 
Sbjct  239  TDKDFTVFTTRPDTLFGATYAVLAPEHALVDA-ITTSDQAEAVADYKRQASLKSDLARTD  297

Query  299  DDLEKEGVFTGQYCINPLTGREMPIYVANFVLMGYGTGAVMAVPAHDQRDFEFAAKYDLP  358
               EK GV TG Y INP+ G+EMP+ +A++VL +YGTGA+MAVPAHD+RD EFA +++L 
Sbjct  298  LAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNL-  356

Query  359  KQIVIMPREGALDLATMTEAFTDPGVMANSGEFDGMDSEAAKKAIIDHLAAGGLGKPTVN  418
             +I+ +   G ++      AFT+ G+  NS+ +DG+D  +A   +++ L A G+G+  V 
Sbjct  357  -DIIPVLEGGNVE----EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVT  411

Query  419  YRLRDWNISRQRYWGAPIPVIYCDDCGIVPVPASQLPVELPL--DVKVNADGRSPLPGCE  476
            YRLRDW +SRQRYWG PIP+I  +D    +VP S+LP+ LP+  D++ ++ G SPL+   
Sbjct  412  YRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVT  471

Query  477  SFVNVPCPTCGKPARRETDTMDTFVESSWYFARYTSARNETTAFDPAEVAYWMPVDQYIG  536
              ++V      K +RRET+TM     SSWY+ RY  ++N     D   +  W+PVD Y+G
Sbjct  472  DWLEVTREDGVK-GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVG  530

Query  537  GIEHAILHLLYSRFFVKALRDEGYLTHDEPFKNLLTQGMVL-------------------  577
            G EHA+LHLLY+RF  K L D G +   EPF++L+ QGM+L                   
Sbjct  531  GAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEK  590

Query  578  -----LH----------GSKMSKSKGNVVDPDEMIAKYGADTVRLFCLFAAPPEKDLEWN  622
                 +H           +KMSKS  NVV+PD+++ +YGADT+R++ +F +P +  + W+
Sbjct  591  RDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWS  650

Query  623  DKGIEGASRFLNRLWRLVDELDDVLSPVGTCVSVEGTLGESEAELRRKEHDTVRRVERDI  682
            + G+EG+ +FL+R+ RL              ++      E+ + L +  ++TV+ V  ++
Sbjct  651  EEGLEGSRKFLDRVYRL--------------ITTKEITEENSGALDKVYNETVKAVTEQV  696

Query  683  ENKFQFNTAIAAMMELVNSLYATKDDLRASKNGPRLLSSAISSLLVTLSPIAPHVCEEVW  742
            ++  +FNTAIA +M +VN+  A K+D        +L+S    +++  ++P+APH+ EE+W
Sbjct  697  DQM-KFNTAIAQLMVFVNA--ANKED--------KLFSDYAKGFVQLIAPFAPHLGEELW  745

Query  743  DRM-GYTRTLAAEPWPAHDPEALRTSEVTVVLQVNGKLRSQITVAADATSEEIETQAMND  801
            + + +   +++  PWP+ D   L  ++V +V+Q++GK+++++ VA D + EE++  A+ +
Sbjct  746  QALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALAN  805

Query  802  QNVSRHIEGKTIVKTIVIPGKLVNVVVR  829
            ++V  +I GK I+K I +P KLVN+V++
Sbjct  806  EKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

1051) HMPREF0409_01679 in NC_021281


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  548 bits (2070),  Expect = 5e-157, Method: Compositional matrix adjust.
 Identities = 352/848 (42%), Positives = 545/848 (65%), Gaps = 50/848 (5%)

Query  17   YEFKQIEKKWQERWSKDNIFKTENEVEGKENYYVLSMLPYPSGK-LHVGHARNYTIGDVI  75
            Y+   IE KWQ  W+ ++ FKT  +  +K ++Y L M+PYPSG  LHVGH+  YT  D++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDA-SKPKFYALDMFPYPSGAGLHVGHPEGYTATDIL  62

Query  76   SRYKRMKGYNVLQPMGWDSFGLPAENAAIQNGTHPAIWTKSNIENMKRQLKLMGFSYDWE  135
            SR+KR +G NVL+PMGWD+FGLPAE+ A++ G +PA  T  NI N KRQ++ +GFSYDW+
Sbjct  63   SRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWD  122

Query  136  REIASYTPEYYKWNQWLFKRMYEKGLIYKKKSLVNWCPDCQTVLANEQV-EDGMCWRHSK  194
            RE+ +  P+YYKW QW+F ++YEKGL Y     VNW  +  T +ANE+V  DG    ++ 
Sbjct  123  REVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTS-ERGG  181

Query  195  THVIQKELEQWFFKITDYADELLEGHEEIKDGWPEKVLTMQKNWIGKSFGTELKLKVVET  254
              V++K + QW +KIT YA+ LLE+ EE+  +WPE +  MQ+NWIGKS G+++ +KV +T
Sbjct  182  YPVVRKPMRQWMLKITAYAERLLEDLEEV--DWPESIKDMQRNWIGKSTGANVTFKVKDT  239

Query  255  GEDLPIFTTRIDTIYGVSYAVVAPEHPIVEKILKVNPSIKDKVTEMKNTDI----IERGA  310
            + D+ +FTTR DT++G +YAV+APEH++V+ I   + +  + V++ K        + R  
Sbjct  240  DKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQA--EAVADYKRQASLKSDLARTD  297

Query  311  EGREKNGIDSGWHIENPVNKEIVPLWIADYVLMNYGTGAVMGVPAHDERDFVFAGKYNLP  370
             ++EK G+ +G    NPVN   +P+WIADYVL +YGTGA+M+VPAHDERD  FA ++NL 
Sbjct  298  LAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLD  357

Query  371  VKQVITSKKTDEKVELPYLEEGVMINSGEFNGLNSKEALVKIAEYVEEKGYGQRTYKYRL  430
            +  V+ + + +E    ++ E+G+ INS+ ++GL+   A+ K+ E +E  G G+    YRL
Sbjct  358  IIPVLEGGNVEEA---AFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRL  414

Query  431  KDWGISRQRYWGTPIPVLYCEKCGEVLEKDENLPVLLP--DDIEFSGSGN-PLETSNKFK  487
            +DW +SRQRYWG PIP++  E        + +LP++LP   DI  SG+G+ PL       
Sbjct  415  RDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWL  474

Query  488  EATCPCCGGKARRDTDTMDTFVDSSWYFLRYCDPKNLNLPFSKEIVDKWTPVDQYIGGVE  547
            E T    G K+RR+T+TM    +SSWY+LRY DP N +     E++ +W PVD Y+GG E
Sbjct  475  EVTRE-DGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAE  533

Query  548  HAVMHLLYARFFYKVLRDLGLLSSNEPFKRLLTQGMVLGPSYYSEKENKYLFSKDVVIKG  607
            HAV+HLLYARF  KVL DLG+++++EPF++L+ QGM+LG SY   +    L + D V K 
Sbjct  534  HAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGA--LVATDKVEKR  591

Query  608  DKAY--SQSGEELQVKVEKMSKSKNNGVDPEEMLDKYGADTTRLFIMFAAPPEKELEWNE  665
            D ++   ++GEEL+    KMSKS +N V+P++++++YGADT R++ MF +P +  + W+E
Sbjct  592  DGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSE  651

Query  666  NGLAGAYRFLTRVWRLVFENSEIVKKSNDKIDYNKLSKEDKALLIKL-NQTIKKVTDAIE  724
            +GL G+ +FL RV RL              I  + ++ E+ + L K+ N+T+K VT+ ++
Sbjct  652  EGLEGSRKFLDRVYRL--------------ITTKEITEENSGALDKVYNETVKAVTEQVD  697

Query  725  NNYHFNTAIAANMELINEVQTYVASSMNSEQAAKILGYTLKKIIIMLSPFVPHFCDEIWE  784
            +   FNTAIA  M ++N           +++  K+++   K ++ +++PF PH+ +E+W+
Sbjct  698  QM-KFNTAIAQLMVFVN----------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  785  ELGEKGYLFN-EKWPEYDEKMLSSDETTIAVQVNGKVRGSFEIAKDSDKALVEKTALELP  843
             L   G  ++   WP YDE  L  ++  I VQ++GKV++ + +AKD  +  ++  AL   
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  844  NVAKHLEG  851
            +V  ++ G
Sbjct  807  KVQAEIAG  814

1052) Dalk_1193 in NC_011768


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  548 bits (2069),  Expect = 5e-157, Method: Compositional matrix adjust.
 Identities = 345/849 (41%), Positives = 542/849 (64%), Gaps = 40/849 (4%)

Query  5    YDPKKIEGKWQAHWDAAGLFKVKEDPSKEKYFLMEMFPYPSGK-IHMGHVRNYSIGDVVA  63
            YD   IE KWQA W     FK   D+SK K++ ++MFPYPSG  +H+GH   Y+  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RFKRMQGFNVLHPMGWDAFGMPAENAAIKNNTHPAKWTYENIAAMGAQLKAMGFSYDWDR  123
            RFKR QG NVLHPMGWDAFG+PAE+ A+    +PA  T ENIA    Q++A+GFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EIATCKPDYYRWEQWLFVQMFKKGMVYRKEASVNWCHTCQTVLANEQV-EQNMCWRCGDE  182
            E+ T  P+YY+W QW+F +++ KG+ Y  E +VNW +   T +ANE+V  +    R G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VEQKKLKQWFFRITDYADDLLEHCDKLPGWPEKVVTMQKNWIGKSHGAEILFSVKDSDVK  242
            V +K ++QW ++IT YA+ LLE+ + + +WPE +  MQ+NWIGKS GA++ F VKD+D  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  IKVFTTRPDTLCGATFMCLAPEHPLVEDLSKGTAQEAVVQEFVARMAKQDKAKRTADDKE  302
            + VFTTRPDTL GAT+  LAPEH+LV+ ++  + Q   V ++  + + +    RT   KE
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITT-SDQAEAVADYKRQASLKSDLARTDLAKE  301

Query  303  KEGVPIGAQCINPLTGKTMEIYTANFALMEYGTGAVMSVPTHDQRDFEFATKYGLEKIVV  362
            K GV  G+  INP+ GK M +  A++ L  YGTGA+M+VP+HD+RD EFA ++ L+ I V
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  363  IQPEGEALSPETMTEAYTDPGVLVNSGQFDGMKNTDAMEAIAQYLDENDMGKKTVQYRIR  422
            ++      + +    A+T+ G+ +NS+ +DG+ ++ A+  + + L+ +++G+  V YR+R
Sbjct  362  LE------GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  423  DWGISRQRYWGAPIPMIHCPDCGITPVPEDQLPVILPEDANL--LEGGKSPLPELDSFVK  480
            DW +SRQRYWG PIP+IH  D   T+VPE +LP++LP   ++     G SPL+++   + 
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  481  TTCPQCGNENARRETDTMDTFVESSWYPERYCSPKCDDGMFDVDAVKYWMPVDQYIGGVE  540
             T  +    ++RRET+TM     SSWY  RY  P   + + D + +K W+PVD Y+GG E
Sbjct  476  VTREDGV--KGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAE  533

Query  541  HAVMHLLYSRYFTRVLNDFGLVDFKEPFTRLLTQGMVCKETLKCPEHGWLFPHEVEGSGD  600
            HAV+HLLY+R+  +VL D+G+V  KEPF +L+ QGM+   + + +  + +  + VE  ++
Sbjct  534  HAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDG  593

Query  601  ERTCTKCGKIVEAGRVEKMSKSKLNVVDPEELLAKYGADTIRLFCLFAAPPERDLDWSEE  660
                   G  +E +   KMSKS  NVV+P++++ +YGADT+R++ +F +P +  + WSEE
Sbjct  594  SFFHVETGEELEQAP-AKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEE  652

Query  661  GVEGSYRFLQRVWRMFAAHMDEVKDAQPFEGSPddldgylkdlykkTHQTIKKVTEDIDG  720
            G+EGS +FL+RV R++++      ++ +++              K  ++T+K VTE++D 
Sbjct  653  GLEGSRKFLDRVYRLITTKEITEENSGALD--------------KVYNETVKAVTEQVD-  697

Query  721  RFHFNTAISAVMELVNMVYGLDDNLQGEKRAGVLRAAVEAVILLISPMTPHFTEELW-SL  779
            +  FNTAI+ +M +VN          ++K   ++     + + LI+P +PH+ EELW +L
Sbjct  698  QMKFNTAIAQLMVFVN---------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQAL  748

Query  780  FGKTQCVLETPWPAWREDALTADEVVVVLQVNGKLRSKLNVPLDTDDEKIKEMALADEKV  839
             +  + +   PWP+  E  L  ++V +V+Q++GK+++KL V+ D   E ++E+ALA+EKV
Sbjct  749  TASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKV  808

Query  840  QKFMGGKPI  848
            Q  ++GK I
Sbjct  809  QAEIAGKDI  817

1053) leuS in NC_006461


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  548 bits (2069),  Expect = 6e-157, Method: Compositional matrix adjust.
 Identities = 390/881 (45%), Positives = 566/881 (65%), Gaps = 58/881 (6%)

Query  4    YNPHAIEAKWQRFWEEK-GFMKAKDLPGGRGKQYVLVMFPYPSG-DLHMGHLKNYTMGDV  61
            Y+  AIE+KWQ FW ++  F  + D  +++ K Y L MFPYPSG +LH+GH   YT  D+
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTD--ASKPKFYALDMFPYPSGAGLHVGHPEGYTATDI  61

Query  62   LARFRRMQGYEVLHPMGWDAFGLPAENAALKFGVHPKDWTYENIRQAKESLRLMGILYDW  121
            L+RF+R QG +VLHPMGWDAFGLPAE+ A+  G +P + T ENI + K  +  +G+ YDW
Sbjct  62   LSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDW  121

Query  122  DREVTTCEPEYYRWNQWIFLKMWEKGLAYRAKGLVNWCPKCQTVLANEQVVEGRCWRHED  181
            DREV T +P+YY+W QWIF K+ EKGLAY A   VNW     T +ANE+V+ +    + +
Sbjct  122  DREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGG  181

Query  182  TPVEKRELEQWYLRITAYAERLLKDLEGLNWPEKVKAMQRAWIGRSEGAEILFPVEGKEV  241
             PV ++ + QW L+ITAYAERLL DLE ++WPE +K MQR WIG+S GA++ F V + + 
Sbjct  182  YPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDK  241

Query  242  RIPVFTTRPDTLFGATFLVLAPEHPLTLELAAPEKREEVLAYVEAAKRKTEIERQAEGRE  301
             + VFTTRPDTLFGAT+ VLAPEH+L   ++++++ E V  Y   A  K+++ R   ++E
Sbjct  242  DFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKE  301

Query  302  KTGVFLGAYALNPATGERIPIWTADYVLFGYGTGAIMAVPAHDQRDYEFARKFGLPIKKV  361
            KTGV  G+YA+NP  G  +P+W ADYVL +YGTGAIMAVPAHD+RD EFA++F L I  V
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  362  IerpgeplpeplerAYEEPGIMVNSGPFDGTESEEGKRKVIAWLEEKGLGKGRVTYRLRD  421
            +E      +     A+ E G+ +NS+ +DG +   +  K++ WLE  G+G+  VTYRLRD
Sbjct  362  LEGGNVEEA-----AFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  422  WLISRQRYWGTPIPMVHCEACGvvpvpeeelpvllpdlkdvedIRPKGK--SPLEAHPEF  479
            WL+SRQRYWG PIP++H E     +VPE ELP++LP  KD   IRP G   SPL    + 
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKD---IRPSGTGESPLANVTDW  473

Query  480  YETTCPKCGGPAKRdtdtmdtffdSSWYYLRYTDPHN-DRLPFDPEKANAWMPVDQYIGG  538
             E T    G  ++R+T+TM    +SSWYYLRY DPHN ++L+ D E  + W+PVD Y+GG
Sbjct  474  LEVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLA-DEELLKQWLPVDIYVGG  531

Query  539  VEHAVLHLLYSRFFTKFLHDLGMVKVEEPFQGLFTQGMVLAWTDFGPVEVEGSVVRLPEP  598
             EHAVLHLLY+RF  K L DLG+V   EPFQ LF QGM+L+                   
Sbjct  532  AEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILG-------------------  572

Query  599  TRIRLEIPESALSLENVRKMGAELRPHEDGTLHLWKPAVMSKSKGNGVMVGPFVKEQGAD  658
            T  R +   + ++ ++V K ++ +   E G      PA MSKS  N V  +  V + GAD
Sbjct  573  TSYR-DSRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGAD  631

Query  659  IARITILFAAPPENEMVWTEEGVQGAWRFLNRIYRRVAEDREALLETSGVFQAEALEGKD  718
              R+  +F +P +  + W+EEG++G+++FL+R+YR ++  +E   E SG ++        
Sbjct  632  TLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLIT-TKEITEENSGALD--------  682

Query  719  RELYGKLHETLKKVTEDLEALRFNTAIAALMEFLNALYEYRKDRPVTPVYRTAIRYYLQM  778
              +Y   +ET+K VTE+++ ++FNTAIA LM F+NA     K+  + + Y  +   ++Q+
Sbjct  683  -KVY---NETVKAVTEQVDQMKFNTAIAQLMVFVNAA---NKEDKLFSDYAKG---FVQL  732

Query  779  LFPFAPHLAEELWHWF--WPDSLFEAGWPELDEKALEKDVVEVAVQVNGRVRGTIHIPKD  836
            + PFAPHL+EELW+ +    +S+    WP  DE  L  + VE+ VQ++G+V++ + ++KD
Sbjct  733  IAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKD  792

Query  837  APLEVARAEALKVRNVRAHLEGKEVVKEIYVPGKILNLVVR  877
             + E  +  AL   +V+A++ GK+++K I VP K++N+V++
Sbjct  793  LSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

1054) Ser39006_1828 in NC_022268


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  548 bits (2069),  Expect = 6e-157, Method: Compositional matrix adjust.
 Identities = 359/865 (42%), Positives = 553/865 (64%), Gaps = 46/865 (5%)

Query  5    YRPEEIEAHVQLHWQEKQTFKVTEEPGKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIS  63
            Y    IE+  Q  W +++TFK   +++K K+Y L M+PYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYANIEYMKNQLKLLGFGYDWNR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T  NI   K Q++ LGF+YDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCQPDYYRWEQWFFTKLYEKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T +P+YY+W QW+FTKLYEKGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADQLLNDLDTLESWPEQVKTMQRNWIGRSEGVEITFDVADSDQK  242
            V RK + QW +KITAYA++LL+DL+ ++ WPE +K MQRNWIG+S G ++TF V D+D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGVTYVAVAAGHPLASQ--AAEHNPALQDFIAECR-NTKVAEADMATME  299
            +TV+TTRPDT+ G TY  +A+ H+L     ++++  A+ D+  +   ++ +A +D+A  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGVATGLFAIHPLSGEKVPVWVANFVLMEYGTGAVMAVPGHDQRDWEFATKYHLSIKPV  359
            K GV TG +AI+P++G  +PVW+A++VL  YGTGA+MAVP+HD+RDWEFA +++L I PV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  360  ILVSDGSTPDLSAQAMTEKGRLVNSGEFDGLEFDAAFNAIADKLVELGVGQRKVNYRLRD  419
            +        ++   A TE G  +NS+ +DGL+  +A+  + + L   GVG+ +V YRLRD
Sbjct  362  L-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMITLEDGTVIPAPADQLPIILP--EDVVMDGIT-SPIKADPNWAKT  476
            W  SRQRYWG PIP+I  EDGT  + P  +LP++LP   D+   G   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  T-VNGQPALRETDTFDTFMESSWYYARYTCPQYDQGMLDPAAANYWLPVDQYVGGIEHAI  535
            T  +G  + RET+T      SSWYY RY  P+  + + D    + WLPVD YVGG EHA+
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLMYFRFFHKLMRDAGMVNSDEPAKRLLCQGMVLADAFYYIGTNGERIWISPADVTIER  595
            +HL+Y RF HK++ D G+V + EP ++L+ QGM+L+ +  Y ++ G       A V+ ++
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS--YRDSRG-------ALVATDK  587

Query  596  DEKGRIVKAFDTEGRELVYAGMSKMSKSKNNGIDPQTMVEKYGADTVRLFMMFASPAEMT  655
             EK R    F+ E  E +  + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P + +
Sbjct  588  VEK-RDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  656  LEWQESGVEGANRFLKRVWKQVFDHTGKGATLPLDIASITEDQKSLRRDLHKTIAKVTDD  715
            + W E G+EG+ +FL RV + +   T K  T         E+  +L +  + T+  VT++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLI---TTKEIT--------EENSGALDKVYNETVKAVTEQ  695

Query  716  IGRRQTFNTAIAAIMELMNKLARAPQESIQDRALTQEVLQAVVRMLYPFTPHICFTLWQA  775
            +++ + FNTAIA +M ++N   +       +  L  +  ++ V+++ PF+PH+   LWQA
Sbjct  696  VDQMK-FNTAIAQLMVFVNAANK-------EDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  776  LHGEGD-IDKAPWPIADEQAMVEDSKLVVVQVNGKVRGRITVAAEATEQQVRDRAAQEPL  834
            L + G+ I   PWP  DE  +VE+   +VVQ++GKV++++ VA + + +++++ A  +  
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  835  VAKYLDGVTVRKVIYVPGKLLNLVV  859
            V   + G  + KVI VP KL+N+V+
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVI  832

1055) leuS in NC_008705


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  548 bits (2068),  Expect = 7e-157, Method: Compositional matrix adjust.
 Identities = 355/732 (49%), Positives = 494/732 (68%), Gaps = 54/732 (7%)

Query  247  LVYRADSMVNWCPGLGTVLANEEVTADGRSDRGNFPVFRKRLRQWMMRITAYSDRLLEDL  306
            L Y A+  VNW   LGT +ANEEV +DG S+RG +PV RK +RQWM++ITAY++RLLEDL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  307  EVLDWPDKVKTMQRNWIGRSTGASVQFGTDAGDIE--VFTTRPDTLFGATYLVLAPEHPL  364
            E +DWP+ +K MQRNWIG+STGA+V F     D +  VFTTRPDTLFGATY VLAPEH+L
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  365  VEQLAAEQWPDDVDGRWTFGATTPREAVAAYRASIAAKSDLERQE-NKTKTGAFLGAYAT  423
            V+ +++               +   EAVA Y+   + KSDL R +  K KTG   G+YA 
Sbjct  268  VDAITT---------------SDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAI  312

Query  424  NPANGQQVPIFIADYVLIGYGTGAIMAVPGHDQRDWEFAHEFGLPVVEVISGGDISEAAY  483
            NP NG+++P+ IADYVL +YGTGAIMAVP+HD+RDWEFA +F L ++ V+ GG++ EAA+
Sbjct  313  NPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEAAF  372

Query  484  AGDGLLVNSDYLDGLDVAAAKAAITDRLVADGRGRARVEYKLRDWLFARQRYWGEPFPIV  543
            + DGL +NSD+LDGLD A+A A + ++L A+G G   V Y+LRDWLF+RQRYWGEP+PI+
Sbjct  373  TEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPII  432

Query  544  YDSDGRPHPLPESALPVELPDVPDYSPVLFDPDDADSEPNPPLNKATDWVHVELDLGDGL  603
               DG + ++PES LP+ LP   D  P         +  ++PL + TDW++V  +  DG+
Sbjct  433  HWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTDWLEVTRE--DGV  482

Query  604  QTYTRDTNVMPQWAGSSWYELRYTDPLNKEALCAKENEAYWMGPQPAEHGPDDPGGVDLY  663
            +   R+TN MPQWAGSSWY LRY DP N E L   E    W+              VD+Y
Sbjct  483  KG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWL-------------PVDIY  528

Query  664  VGGVEHAVLHLLYSRFWHKVLYDLGHVSSREPYRRLVNQGYIQAFAYTDSRGSYVPAAEV  723
            VGG EHAVLHLLY+RFWHKVLYDLG V+++EP+++L NQG I + +Y DSRG+ V++  V
Sbjct  529  VGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKV  588

Query  724  VERDGKFWFE---GAEVFQEFGKIGKSLKNSVSPDEICDNYGADTLRVYEMSMGPLEASR  780
              RDG F F+   G E+ Q  +K++KSLKN V+PD++ ++YGADTLRVYEM MGPL+AS 
Sbjct  589  EKRDGSF-FHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASI  647

Query  781  PWATKDVVGAHRFLQRVWRLVVDEQSGAVRVANHEALDTDTLRALHRTVAGVSEDYAALR  840
            +W+  ++ G+++FL+RV RL+   +   +   N  ALD    +  + TV +V+E+   ++
Sbjct  648  AWSEEGLEGSRKFLDRVYRLITTKE---ITEENSGALD----KVYNETVKAVTEQVDQMK  700

Query  841  NNTAAAKLIEYTNHLTKEGVTARAAIEPLVLMVAPLAPHLAEELWRRL-GHDTSLAHGPF  899
             NTA A+L+ + N   KE+         +V ++AP+APHL+EELW+ L + + S++  P 
Sbjct  701  FNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPW  760

Query  900  PVADPQYLVTDTVEYPVQVNGKVRSRITVDADAGKDTLEAAALADEKVQAFLNGATPKKV  959
            P  D   LV + VE  VQ++GKV++++ V  D +++ L+  ALA+EKVQA + G    KV
Sbjct  761  PSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKV  820

Query  960  IVVPGRLVNLVV  971
            I VP +LVN+V+
Sbjct  821  IAVPNKLVNIVI  832


 Score =  126 bits (460),  Expect = 1e-29, Method: Compositional matrix adjust.
 Identities = 75/147 (52%), Positives = 100/147 (69%), Gaps = 10/147 (6%)

Query  51   IEGAWQQTWAVEGTFNVPNPVGELAPPDGTVPADKMFVQDMFPYPSGEGLHVGHPLGYIA  110
            IE  WQ  WA + TF+        +  D++ P  K +  DMFPYPSG GLHVGHP GY A
Sbjct  9    IEPKWQAFWADNHTFK--------TGTDASKP--KFYALDMFPYPSGAGLHVGHPEGYTA  58

Query  111  TDVYARYYRMTGRNVLHALGFDAFGLPAEQYAVQTGTHPRTRTEANIVNFRRQLGRLGLG  170
            TD+ +R+ R  G+NVLH++G DAFGLPAEQYA++TG +P   T  NI NF+RQ+  LG++
Sbjct  59   TDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFS  118

Query  171  HDTRRSFSTTDVDFYTWTQWIFLQIYN  197
             D  R  +TTD ++Y WTQWIF ++Y+
Sbjct  119  YDWDREVNTTDPNYYKWTQWIFTKLYE  145

1056) leuS in NC_008146


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  548 bits (2068),  Expect = 7e-157, Method: Compositional matrix adjust.
 Identities = 355/732 (49%), Positives = 494/732 (68%), Gaps = 54/732 (7%)

Query  247  LVYRADSMVNWCPGLGTVLANEEVTADGRSDRGNFPVFRKRLRQWMMRITAYSDRLLEDL  306
            L Y A+  VNW   LGT +ANEEV +DG S+RG +PV RK +RQWM++ITAY++RLLEDL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  307  EVLDWPDKVKTMQRNWIGRSTGASVQFGTDAGDIE--VFTTRPDTLFGATYLVLAPEHPL  364
            E +DWP+ +K MQRNWIG+STGA+V F     D +  VFTTRPDTLFGATY VLAPEH+L
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  365  VEQLAAEQWPDDVDGRWTFGATTPREAVAAYRASIAAKSDLERQE-NKTKTGAFLGAYAT  423
            V+ +++               +   EAVA Y+   + KSDL R +  K KTG   G+YA 
Sbjct  268  VDAITT---------------SDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAI  312

Query  424  NPANGQQVPIFIADYVLIGYGTGAIMAVPGHDQRDWEFAHEFGLPVVEVISGGDISEAAY  483
            NP NG+++P+ IADYVL +YGTGAIMAVP+HD+RDWEFA +F L ++ V+ GG++ EAA+
Sbjct  313  NPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEAAF  372

Query  484  AGDGLLVNSDYLDGLDVAAAKAAITDRLVADGRGRARVEYKLRDWLFARQRYWGEPFPIV  543
            + DGL +NSD+LDGLD A+A A + ++L A+G G   V Y+LRDWLF+RQRYWGEP+PI+
Sbjct  373  TEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPII  432

Query  544  YDSDGRPHPLPESALPVELPDVPDYSPVLFDPDDADSEPNPPLNKATDWVHVELDLGDGL  603
               DG + ++PES LP+ LP   D  P         +  ++PL + TDW++V  +  DG+
Sbjct  433  HWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTDWLEVTRE--DGV  482

Query  604  QTYTRDTNVMPQWAGSSWYELRYTDPLNKEALCAKENEAYWMGPQPAEHGPDDPGGVDLY  663
            +   R+TN MPQWAGSSWY LRY DP N E L   E    W+              VD+Y
Sbjct  483  KG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWL-------------PVDIY  528

Query  664  VGGVEHAVLHLLYSRFWHKVLYDLGHVSSREPYRRLVNQGYIQAFAYTDSRGSYVPAAEV  723
            VGG EHAVLHLLY+RFWHKVLYDLG V+++EP+++L NQG I + +Y DSRG+ V++  V
Sbjct  529  VGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKV  588

Query  724  VERDGKFWFE---GAEVFQEFGKIGKSLKNSVSPDEICDNYGADTLRVYEMSMGPLEASR  780
              RDG F F+   G E+ Q  +K++KSLKN V+PD++ ++YGADTLRVYEM MGPL+AS 
Sbjct  589  EKRDGSF-FHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASI  647

Query  781  PWATKDVVGAHRFLQRVWRLVVDEQSGAVRVANHEALDTDTLRALHRTVAGVSEDYAALR  840
            +W+  ++ G+++FL+RV RL+   +   +   N  ALD    +  + TV +V+E+   ++
Sbjct  648  AWSEEGLEGSRKFLDRVYRLITTKE---ITEENSGALD----KVYNETVKAVTEQVDQMK  700

Query  841  NNTAAAKLIEYTNHLTKEGVTARAAIEPLVLMVAPLAPHLAEELWRRL-GHDTSLAHGPF  899
             NTA A+L+ + N   KE+         +V ++AP+APHL+EELW+ L + + S++  P 
Sbjct  701  FNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPW  760

Query  900  PVADPQYLVTDTVEYPVQVNGKVRSRITVDADAGKDTLEAAALADEKVQAFLNGATPKKV  959
            P  D   LV + VE  VQ++GKV++++ V  D +++ L+  ALA+EKVQA + G    KV
Sbjct  761  PSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKV  820

Query  960  IVVPGRLVNLVV  971
            I VP +LVN+V+
Sbjct  821  IAVPNKLVNIVI  832


 Score =  126 bits (460),  Expect = 1e-29, Method: Compositional matrix adjust.
 Identities = 75/147 (52%), Positives = 100/147 (69%), Gaps = 10/147 (6%)

Query  51   IEGAWQQTWAVEGTFNVPNPVGELAPPDGTVPADKMFVQDMFPYPSGEGLHVGHPLGYIA  110
            IE  WQ  WA + TF+        +  D++ P  K +  DMFPYPSG GLHVGHP GY A
Sbjct  9    IEPKWQAFWADNHTFK--------TGTDASKP--KFYALDMFPYPSGAGLHVGHPEGYTA  58

Query  111  TDVYARYYRMTGRNVLHALGFDAFGLPAEQYAVQTGTHPRTRTEANIVNFRRQLGRLGLG  170
            TD+ +R+ R  G+NVLH++G DAFGLPAEQYA++TG +P   T  NI NF+RQ+  LG++
Sbjct  59   TDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFS  118

Query  171  HDTRRSFSTTDVDFYTWTQWIFLQIYN  197
             D  R  +TTD ++Y WTQWIF ++Y+
Sbjct  119  YDWDREVNTTDPNYYKWTQWIFTKLYE  145

1057) leuS in NC_011138


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  548 bits (2067),  Expect = 7e-157, Method: Compositional matrix adjust.
 Identities = 358/874 (41%), Positives = 560/874 (65%), Gaps = 56/874 (6%)

Query  6    YNPKDIEQRVQQYWEENQSFKANDDVEKEKFYCLSMFPYPSGR-LHMGHVRNYTIGDVIS  64
            Y+   IE + Q +W +N++FK+  D  K KFY L MFPYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  65   RFQRMQGKNVLQPMGWDAFGLPAENAAINNNTAPAKWTYSNIDYMKNQLRSLGFGYDWDR  124
            RF+R QG NVL+PMGWDAFGLPAE+ A++    PA  T  NI   K Q+ +LGF+YDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  125  EVTTCKSDYYRWEQWFFTRLYEKGLVYKKNSTVNWDPVDQTVLANEQVI-DGRGWRSGAL  183
            EV T  ++YY+W QW+FT+LYEKGL Y  +  VNW     T +ANE+V+ DG + R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  184  VEQKEIPQWFIKITDYAeellqdleqleeWPDQVRAMQANWIGRSEGVEITFDLASAVND  243
            V +K + QW +KIT YA E L +  +  +WP+ ++ MQ NWIG+S G ++TF +  + + 
Sbjct  184  VVRKPMRQWMLKITAYA-ERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDK-  241

Query  244  IADLTVYTTRPDTFYGVTYVAVAAQHPLAEFAAQSNPDLAAFIEECKNTKVAEAELA---  300
              D+TV+TTRPDT++G TY  +A++H+L +  A + +D A  + + K      ++LA   
Sbjct  242  --DFTVFTTRPDTLFGATYAVLAPEHALVD--AITTSDQAEAVADYKRQASLKSDLARTD  297

Query  301  -TMEKKGFATGFEVIHPLTGEKLPIWVANFVLMDYGSGAVMAVPGHDQRDWEFATKYDLP  359
             + EK G  TG   I+P+ G  +P+W+A++VL  YG+GA+MAVP+HD+RDWEFA +++L 
Sbjct  298  LAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLD  357

Query  360  ITQVIAPNAGDEDKCDLSASAYTEKGSLINSDKFNGLEFDAAFNGIADELEGKGCGKRKV  419
            I  V+     +E       +A+TE G  INSD ++GL+  +A+  + + LE+ G G+ +V
Sbjct  358  IIPVLEGGNVEE-------AAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENV  410

Query  420  NYRLRDWGVSRQRYWGAPIPMLNLENGESVPVPADQLPVVLP--EDVEMNGVT-SPIKAD  476
             YRLRDW  SRQRYWG PIP+++ E+G S +VP  +LP+VLP   D+  +G   SP+   
Sbjct  411  TYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANV  470

Query  477  PEWAKTTY-NGEAALRETDTFDTFMESSWYYARYASATNNDAMLDPTSANYWLPVDQYIG  535
             +W   T  +G  + RET+T      SSWYY RY  + N + + D    + WLPVD Y+G
Sbjct  471  TDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVG  530

Query  536  GIEHAILHLLYSRFFHKLLRDEGLVNSDEPFKRLLCQGMVLADSYYREDKAGKKTWFSPT  595
            G EHA+LHLLY+RF HK+L D G+V + EPF++L+ QGM+L+ S YR+ +++        
Sbjct  531  GAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS-YRDSRGAL-------  582

Query  596  EVSTEKDDKGRIVKAWLTADGEEVIHGGMTKMSKSKNNGIDPQEVIDLYGADTVRLFTMF  655
             V+T+K +K     + +  +  E ++ + +KMSKS +N ++P++V++ YGADT+R++ MF
Sbjct  583  -VATDKVEKRD--GSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMF  639

Query  656  AAPPEQTLEWVDSGVEGANRFLRRIWKLVTEHVEKGTPEAIDVKSLSKDQQ-ALRREVHK  714
             +P + ++ W + G+EG+ +FL R+ +L+T             K ++ ++  AL +  + 
Sbjct  640  MGPLDASIAWSEEGLEGSRKFLDRVYRLIT------------TKEITEENSGALDKVYNE  687

Query  715  TIEKVSDDLGRRQTFNTAVAAVMELLNHLQKAPQESAQDIAIMREACESILLLLNPITPH  774
            T+  V++++++ + FNTA+A +M ++N  +K  +       +  +   +++ L+ P++PH
Sbjct  688  TVKAVTEQVDQMK-FNTAIAQLMVFVNAANKEDK-------LFSDYAKGFVQLIAPFAPH  739

Query  775  IAHELWKVL-GHSEDIDSAPWPQADKAALVEDEKLIIVQVNGKVRAKMTITadaskeaie  833
            +++ELW+ L + +E I   PWP  D + LVE++  I+VQ++GKV+AK+ ++ D S+E ++
Sbjct  740  LGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQ  799

Query  834  asakeQPNVQQFIEGKTIRKVIVVPGKLVNIVAN  867
              A  + +VQ  I GK I KVI VP KLVNIV +
Sbjct  800  EVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

1058) leuS in NC_009077


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  548 bits (2068),  Expect = 8e-157, Method: Compositional matrix adjust.
 Identities = 355/732 (49%), Positives = 494/732 (68%), Gaps = 54/732 (7%)

Query  247  LVYRADSMVNWCPGLGTVLANEEVTADGRSDRGNFPVFRKRLRQWMMRITAYSDRLLEDL  306
            L Y A+  VNW   LGT +ANEEV +DG S+RG +PV RK +RQWM++ITAY++RLLEDL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  307  EVLDWPDKVKTMQRNWIGRSTGASVQFGTDAGDIE--VFTTRPDTLFGATYLVLAPEHPL  364
            E +DWP+ +K MQRNWIG+STGA+V F     D +  VFTTRPDTLFGATY VLAPEH+L
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  365  VEQLAAEQWPDDVDGRWTFGATTPREAVAAYRASIAAKSDLERQE-NKTKTGAFLGAYAT  423
            V+ +++               +   EAVA Y+   + KSDL R +  K KTG   G+YA 
Sbjct  268  VDAITT---------------SDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAI  312

Query  424  NPANGQQVPIFIADYVLIGYGTGAIMAVPGHDQRDWEFAHEFGLPVVEVISGGDISEAAY  483
            NP NG+++P+ IADYVL +YGTGAIMAVP+HD+RDWEFA +F L ++ V+ GG++ EAA+
Sbjct  313  NPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEAAF  372

Query  484  AGDGLLVNSDYLDGLDVAAAKAAITDRLVADGRGRARVEYKLRDWLFARQRYWGEPFPIV  543
            + DGL +NSD+LDGLD A+A A + ++L A+G G   V Y+LRDWLF+RQRYWGEP+PI+
Sbjct  373  TEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPII  432

Query  544  YDSDGRPHPLPESALPVELPDVPDYSPVLFDPDDADSEPNPPLNKATDWVHVELDLGDGL  603
               DG + ++PES LP+ LP   D  P         +  ++PL + TDW++V  +  DG+
Sbjct  433  HWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTDWLEVTRE--DGV  482

Query  604  QTYTRDTNVMPQWAGSSWYELRYTDPLNKEALCAKENEAYWMGPRPAEHGPDDPGGVDLY  663
            +   R+TN MPQWAGSSWY LRY DP N E L   E    W+              VD+Y
Sbjct  483  KG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWL-------------PVDIY  528

Query  664  VGGVEHAVLHLLYSRFWHKVLYDLGHVSSREPYRRLVNQGYIQAFAYTDSRGSYVPAAEV  723
            VGG EHAVLHLLY+RFWHKVLYDLG V+++EP+++L NQG I + +Y DSRG+ V++  V
Sbjct  529  VGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKV  588

Query  724  VERDGKFWFE---GAEVFQEFGKIGKSLKNSVSPDEICDNYGADTLRVYEMSMGPLEASR  780
              RDG F F+   G E+ Q  +K++KSLKN V+PD++ ++YGADTLRVYEM MGPL+AS 
Sbjct  589  EKRDGSF-FHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASI  647

Query  781  PWATKDVVGAHRFLQRVWRLVVDEQSGAVRVANHEALDTDTLRALHRTVAGVSEDYAALR  840
            +W+  ++ G+++FL+RV RL+   +   +   N  ALD    +  + TV +V+E+   ++
Sbjct  648  AWSEEGLEGSRKFLDRVYRLITTKE---ITEENSGALD----KVYNETVKAVTEQVDQMK  700

Query  841  NNTAAAKLIEYTNHLTKEGVTARAAIEPLVLMVAPLAPHLAEELWRRL-GHDTSLAHGPF  899
             NTA A+L+ + N   KE+         +V ++AP+APHL+EELW+ L + + S++  P 
Sbjct  701  FNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPW  760

Query  900  PVADPQYLVTDTVEYPVQVNGKVRSRITVDADAGKDTLEAAALADEKVQAFLNGATPKKV  959
            P  D   LV + VE  VQ++GKV++++ V  D +++ L+  ALA+EKVQA + G    KV
Sbjct  761  PSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKV  820

Query  960  IVVPGRLVNLVV  971
            I VP +LVN+V+
Sbjct  821  IAVPNKLVNIVI  832


 Score =  125 bits (459),  Expect = 1e-29, Method: Compositional matrix adjust.
 Identities = 75/147 (52%), Positives = 100/147 (69%), Gaps = 10/147 (6%)

Query  51   IEGAWQQTWAVEGTFNVPNPVGELAPPDGTVPADKMFVQDMFPYPSGEGLHVGHPLGYIA  110
            IE  WQ  WA + TF+        +  D++ P  K +  DMFPYPSG GLHVGHP GY A
Sbjct  9    IEPKWQAFWADNHTFK--------TGTDASKP--KFYALDMFPYPSGAGLHVGHPEGYTA  58

Query  111  TDVYARYYRMTGRNVLHALGFDAFGLPAEQYAVQTGTHPRTRTEANIVNFRRQLGRLGLG  170
            TD+ +R+ R  G+NVLH++G DAFGLPAEQYA++TG +P   T  NI NF+RQ+  LG++
Sbjct  59   TDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFS  118

Query  171  HDTRRSFSTTDVDFYTWTQWIFLQIYN  197
             D  R  +TTD ++Y WTQWIF ++Y+
Sbjct  119  YDWDREVNTTDPNYYKWTQWIFTKLYE  145

1059) FN3523_0917 in NC_017449


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  548 bits (2067),  Expect = 8e-157, Method: Compositional matrix adjust.
 Identities = 361/856 (43%), Positives = 551/856 (65%), Gaps = 72/856 (8%)

Query  4    YNFSDIEKSTQDYWRKNDSFKTIEDKNKEKFYCLSMLPYPSGT-LHMGHVRNYTIGDVIA  62
            Y+ + IE   Q +W  N++FKT  D +K KFY L M+PYPSG+ LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYQKMQGKNVLHPMGWDAFGLPAENAAIKHKKSPYEWTKSNIAYMRSQLDSLGFSFDWSR  122
            R+++ QG NVLHPMGWDAFGLPAE+ A+   + P E T  NIA  + Q+++LGFS+DW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EIATCDEGYYKWEQWFFIQLYKKGLAYRKNSVVNWDPVDQTVLANEQVI-DGRGWRSGAL  181
            E+ T D  YYKW QW+F +LY KGLAY  +  VNW     T +ANE+V+ DG + R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VEKKEIPQWFLKITDYADELLQDLTKLDGWPEAVKTMQTNWIGKSKGLTVKFKIKGSNQE  241
            V +K + QW LKIT YA+ LL+DL  +D WPE++K MQ NWIGKS G  V FK+K+++++
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  242  IEVFTTRPDTLMGVSYLGIAPEHPLALEEAKTNFQLAAFIEECKKTSTMEADLA----TQ  297
            + VFTTRPDTL G +Y  +APEH+L   +A T  + A  + + K+ +++ +DLA    ++
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALV--DAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  298  EKKGFKTSIKVIHPISGETIDVWVANFVLMGYGSGAVMSVPAHDQRDWEFAQKYNIPLKQ  357
            EK G  T+   I+P++G  + VW+A++VL +YG+GA+M+VPAHD+RDWEFA+++N+ +  
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  358  VIESNDKKLKIDLEKQAFTEKGILINSGEFDGLNFKNAYQAIKKYLIEQVKGYETTNFRI  417
            V+E+       ++E  AFTE G+ INS+ +DGL+  +A   +   L  +  G E   +R+
Sbjct  361  VLEGG------NVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRL  414

Query  418  HDWGISRQRYWGCPIPMIHCDDCGAVPEKEDNLPVILPTDVTLTEAG---SPLKDIPEFI  474
            +DW +SRQRYWG PIP+IH +D  + +  E +LP++LP    +  +G   SPL ++ + +
Sbjct  415  RDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWL  474

Query  475  NVACPKCGKPAKRETDTFDTFFESSWYYARYTCPTADQMLDQEA--NYWLPVDKYIGGIE  532
            +V+     K ++RET+T      SSWYY RY  P   + L +E   + WLPVD Y+GG E
Sbjct  475  EVTREDGVK-GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAE  533

Query  533  HAIMHLLYARFFHKLMRDQGLVKSDEPFKNLLTQGMVL-------------------KDG  573
            HA++HLLYARF HK++ D G+V + EPF++L+ QGM+L                   +DG
Sbjct  534  HAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDG  593

Query  574  ---------------AKMSKSKGNTVDPQELIDKYGADTVRLFSMFAAPPEQSLEWSETG  618
                           AKMSKS  N V+P++++++YGADT+R++ MF +P + S+ WSE G
Sbjct  594  SFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEG  653

Query  619  VEGANKFLRKVFNYAELNKDIFTKNIALESQKLTKEDKKARFEIHSNLKQAIFDFDKSQF  678
            +EG+ KFL +V+      K+I T + +   +K+ +E  KA   +  ++ Q  F+   +Q+
Sbjct  654  LEGSRKFLDRVYRLIT-TKEI-TEENSGALDKVYNETVKA---VTEQVDQMKFNTAIAQL  708

Query  679  NTVVSACMKILNTLNNYNNLSESVKVEGFSILLRVLAPFTPHLCHYLWQQLNL-GEDILH  737
               V+A  K  + +++Y +        GF   ++++APF+PHL + LWQ L   GE I  
Sbjct  709  MVFVNAANKEDKLFSDYAK--------GF---VQLIAPFAPHLGEELWQALTASGESISY  757

Query  738  TSFPTVDNNALVTDEFLLVVQINGKLKAKLELDASLSPNQVEEVVLADQHVKSFIDDKQI  797
             + P+ D++ LV ++  +VVQI+GK+KAKL +   LS ++++EV LA++ V++ I +K+I
Sbjct  758  VPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDI  817

Query  798  VKVIYVPQKLINIVIK  813
            +KVI VP+KL+NIVIK
Sbjct  818  IKVIAVPNKLVNIVIK  833

1060) leuS in NC_011979


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  548 bits (2067),  Expect = 8e-157, Method: Compositional matrix adjust.
 Identities = 354/859 (42%), Positives = 551/859 (65%), Gaps = 70/859 (8%)

Query  5    YVPARVEEKWQKLWDSNKSFKAEKVEGKSKYYLLEMFPYPSGR-IHMGHVRNYSIGDVIA  63
            Y  + +E KWQ +W  N +FK+    +K+K+Y L+MFPYPSG  +H+GH   Y+  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RFKRMKGFNVLHPMGWDAFGMPAENAAIQHKSHPAKWTYENIDYMRGQLKKMGFSYDWDR  123
            RFKR +G NVLHPMGWDAFG+PAE+ A++  ++PA  T ENI   + Q++ +GFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCNVEYYKWEQLIFLQMLEKGLAYKKKSSVNWCPRCETVLANEQV-EDGSCWRCDSL  182
            E+ T + +YYKW Q IF ++ EKGLAY    +VNW     T +ANE+V  DG+  R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VEQKELEQWSFRITDYAEELLEDTYKLPGWPERVLTMQRNWIGRSTGCEIDFSIEGRKDA  242
            V +K + QW ++IT YAE LLED   + +WPE +  MQRNWIG+STG ++ F + +    
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  IKVFTTRQDTLFGATFMSLAPEHPLALQLTTAENMIVVNAFLDKVKKTDKIKRTAEDFEK  302
            + VFTTR DTLFGAT+  LAPEH+L   +TT+++   V  +  +      + RT    EK
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEK  302

Query  303  EGVFTGSYCINPVTNRRMPIYLANFVLTDYGTGAVMAVPTHDQRDFEFARKYAIAMEVVI  362
             GV TGSY INPV  + MP+ +A++VL+ YGTGA+MAVP+HD+RD EFA+++ + +  V+
Sbjct  303  TGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL  362

Query  363  QPEGGSLDVATMTEAYTAEGIMVNSGRFDGLNSAVAKEQIADFLEQEGLGKKTVNFRLRD  422
              EGG+++ A    A+T +G+ +NS+ +DGL+ A A  ++ + LE EG+G+  V +RLRD
Sbjct  363  --EGGNVEEA----AFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  423  WGISRQRYWGNPIPVIYCDDCGAVPVPAKDLPVVLPMDATF--TGEGGNPLSKIDSFIKT  480
            W +SRQRYWG+PIP+I  +D  + +VP  +LP+VLP+   +  +G G +PL+++   +  
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  481  TCPLCGKDARRETDTMDTFVESSWYFLRYCCPDFACGPLDKGKTEYWMSVDQYIGGIEHA  540
            T    G  +RRET+TM     SSWY+LRY  P+ +    D      W++VD Y+GG EHA
Sbjct  477  TRE-DGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  541  VMHLLYARFFTKVLRDLGYCDINEPFTNLLTQGMVI-------------------KDGS-  580
            V+HLLYARF  KVL DLG    +EPF +L+ QGM++                   +DGS 
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSF  595

Query  581  --------------KMSKSKGNVVDPNALIEKYGADTARLFSLFAAPPEKDLDWSDQGVD  626
                          KMSKS  NVV+P+ ++E+YGADT R++ +F +P +  + WS++G++
Sbjct  596  FHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLE  655

Query  627  GSYRFLNRVWKLVYECLPLISATGPLDAAALTDEGK-TLRRLVHKTIRKVSDDIEDRFHF  685
            GS +FL+RV +L+              +  +T+E   +L ++ + T++ V++++ D+  F
Sbjct  656  GSRKFLDRVYRLI-------------TTKEITEENSGALDKVYNETVKAVTEQV-DQMKF  701

Query  686  NTAIAAIMEMVNAIQAFEPKNQPRNVPVLKEAVESVVLLLAPFVPHFAEELWESL-GHED  744
            NTAIA +M  VNA +        ++  ++ +   + V L+APF PH++EELW++L +  +
Sbjct  702  NTAIAQLMVFVNAAN--------KEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGE  753

Query  745  NLNEAAWPAFdaaaavdeellvvvQVNGKLRGKVTVAASATDEDIKGAVLADEKIRQLID  804
            +++  +WP++D +  V++++ +VVQ++GK+++K+ VA   + E+++   LA+EK++  I 
Sbjct  754  SISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIA  813

Query  805  GMNIKKIVYVPGKLVNIVV  823
            G +I K++ VP KLVNIV+
Sbjct  814  GKDIIKVIAVPNKLVNIVI  832

1061) leuS in NC_017506


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  548 bits (2067),  Expect = 8e-157, Method: Compositional matrix adjust.
 Identities = 355/868 (41%), Positives = 552/868 (64%), Gaps = 49/868 (5%)

Query  5    YNPRDVEQNARDFWEENKTFMVKEEPGKPKYYCLSMFPYPSGK-LHMGHVRNYTIGDVIS  63
            Y+   +E + + FW +N TF    +++KPK+Y L MFPYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMQGKNVMQPMGWDAFGLPAENAAIANKTAPAKWTYANIEYMKNQLKQLGFGYDWDR  123
            R++R QG NV++PMGWDAFGLPAE+ A+     PA  T  NI   K Q++ LGF+YDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCKPDYYRWEQWFFARLYEKGLVYKKMSTVNWDPVDQTVLANEQVV-DGRGWRSGAL  182
            E+ T  P+YY+W QW+F++LYEKGL Y     VNW     T +ANE+V+ DG + R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VEQKKIPQWFIRITDYAeellndldqledWPEQVKTMQRNWIGKSEGTELTFPLKDRDSG  242
            V +K + QW ++IT YA E L +  +  DWPE +K MQRNWIGKS G+++TF +KD D +
Sbjct  184  VVRKPMRQWMLKITAYA-ERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTLMGVSYMAVAAEHPLAKEAAERHRDVAEFVEECRNSKTAEAELA----TM  298
            +TV+TTRPDTL G +Y  +A+EH+L    +  ++  AE V + +   +  ++LA    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQ--AEAVADYKRQASLKSDLARTDLAK  300

Query  299  EKRGIDTGFKAIHPLTQEEIPIWVANFVLTDYGTGALMAVPGHDERDHEFARKYKLPIKQ  358
            EK G+ TG  AI+P+   E+P+W+A++VL+ YGTGA+MAVP+HDERD EFA++++L I  
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VIAARDGREIDVQEEAFSEKGTLVSSGKYSGLTSEEAFDEIASYLEEQNIGKRTVNYRLR  418
            V+ +      +V+E AF+E G  ++S+   GL    A+  +   LE + +G+  V YRLR
Sbjct  361  VLEGG-----NVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  419  DWGVSRQRYWGAPIPMMTLEDGTEMPVPDDKLPVRLPEDVEM---DGVQSPIKADPEWCK  475
            DW  SRQRYWG PIP++  EDGT  +VP+  LP+ LP   ++   +  +SP+    +W  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  476  -TEFNGQPATLETDTFDTFMESSWYYARFCSPNYDQGMLDPSAANYWLPVDQYIGGIEHA  534
             T  +G  +  ET+T      SSWYY R+  P+  + + D    + WLPVD Y+GG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  535  ILHLLYARFFHKLLRDVGLVTSSEPFNRLLCQGMVLAETYYRDDGKGGKVWISPADVTVE  594
            +LHLLYARF HK+L D+G+V + EPF++L+ QGM+L+ +Y   D++G+        V+ +
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY--RDSRGAL-------VATD  586

Query  595  RDEKGQPVRAVHREDGEPVVSGGVTKMSKSKNNGIDPQAIIDEHGADTVRLFMMFAAPPE  654
            + EK +     H E GE  +  + +KMSKS +N ++P+ ++++ GADT+R++ MF +P +
Sbjct  587  KVEK-RDGSFFHVETGEE-LEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLD  644

Query  655  QSLEWSDSGVEGAHRFLKRVWRLVNEHavagpapaldaaSLNDDQKNLRRKTHETIAKVS  714
             S+ WS+ G+EG+++FL RV RL+    ++           +++   L +  +ET+  V+
Sbjct  645  ASIAWSEEGLEGSRKFLDRVYRLITTKEIT-----------EENSGALDKVYNETVKAVT  693

Query  715  DDISRRLTFNTAIAAVMELLNEVGKLQGDEPQTRAVRQEALDTAVLVLSPIVPHICHTLW  774
            +++  ++ FNTAIA +M ++N   K          +  +     V +++P+ PH+ + LW
Sbjct  694  EQVD-QMKFNTAIAQLMVFVNAANK-------EDKLFSDYAKGFVQLIAPFAPHLGEELW  745

Query  775  QAL-GHQEPVVDAPWPKADEAAMVRSQIQVVLQVNGKVRAKEDVPADISKADLEKLALEN  833
            QAL +  E++   PWP  DE+ +V +++++V+Q++GKV+AK  V+ D+S+ +L+ +AL N
Sbjct  746  QALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALAN  805

Query  834  ENVMRFTEGATVRKVIVVPGKLVNVVAN  861
            E+V     G  + KVI VP KLVN+V +
Sbjct  806  EKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

1062) Kkor_0323 in NC_013166


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  547 bits (2065),  Expect = 1e-156, Method: Compositional matrix adjust.
 Identities = 381/879 (44%), Positives = 554/879 (64%), Gaps = 58/879 (6%)

Query  12   YQPSEIEGKIQQKWEQNKTFKAVEDASREKYYCLSMFPYPSGR-LHMGHVRNYTIGDVIS  70
            Y+ + IE K Q  W +N TFK+  DAS+ K+Y L MFPYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  71   RFQRMQGKNVLQPIGWDAFGLPAENAAVKNKASPAPWTYENIEYMKGQLKMLGFAYDWDR  130
            RF+R QG NVL+P+GWDAFGLPAE+ A+     PA  T ENI   K Q++ LGF+YDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  131  ELATCKPEYYRWEQWFFTKLYEKGLVYKKTSSVNWCPNDQTVLANEQVV-DGACWRCDTP  189
            E+ T  P+YY+W QW+FTKLYEKGL Y    +VNW  +  T +ANE+V+ DG+  R + P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  190  VEQKEIPQWFIKITAYAEELLNDLDKLDGWPEMVKTMQRNWIGRSEGVEVEFSVETGDES  249
            V +K + QW +KITAYAE LL+DL+ +D WPE +K MQRNWIG+S G +V F V   D  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  250  ENGNGIEPLHVYTTRPDTLYGVTY--LavaaahplatkaaKSNSELAAFV-DECKHSKMS  306
                    + V+TTRPDTL+G TY  LA   A   A  ++     +A +  +    S ++
Sbjct  243  --------FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLA  294

Query  307  EADMATMEKKGMPTGVYAIHPLSGKKVPVWVANFVLMDYGTGAVMAVPGHDQRDYEFATK  366
             +D+A  EK G+ TG YAI+P++GK +PVW+A++VL  YGTGA+MAVP+HD+RD EFA +
Sbjct  295  RTDLA-KEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQ  353

Query  367  YGIDIAPVVKPADGSELDISEQAHTEKGVLFNSGEFDGLDFEKAFAAITAKLEAEGKGKK  426
            + +DI PV+  +     ++ E A TE G+ +NS+ +DGLD   A+A +   LEAEG G+ 
Sbjct  354  FNLDIIPVLEGG-----NVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNE  408

Query  427  TVNYRLRDWGVSRQRYWGAPIPMVNMPDGSVVAAPEDQLPVRLP--EDVVMDGVT-SPLN  483
             V YRLRDW  SRQRYWG PIP+++  DG+  A PE +LP+ LP   D+   G   SPL 
Sbjct  409  NVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLA  468

Query  484  TDEEWKKAI-VDGVEGVRETDTFDTFMESSWYYARYTSTGYDEGMLDPEQANYWLPVDQY  542
               +W      DGV G RET+T      SSWYY RY      E + D E  + WLPVD Y
Sbjct  469  NVTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIY  528

Query  543  IGGIEHATMHLMYFRFFHKLLRDAGLVNSDEPAKQLLCQGMVLADAFYYTDDKGARHWVS  602
            +GG EHA +HL+Y RF HK+L D G+V + EP ++L+ QGM+L+ +  Y D +GA     
Sbjct  529  VGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS--YRDSRGA-----  581

Query  603  PLEVEVVERDDKGRITKAVDSEGREVTHAGMTKMSKSKNNGIDPQSMVDEYGADTMRLYT  662
               +   ++ +K R     + E  E  + + +KMSKS +N ++P+ +V++YGADT+R+Y 
Sbjct  582  ---LVATDKVEK-RDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYE  637

Query  663  MFASPPDQALEWQDSAVEGSLRFLRRLWKLVQSHQQKGQVAKLDVTSLNNDQKALRRKTH  722
            MF +P D ++ W + ++EGS +FL R+ +L+ + +             +++  AL +  +
Sbjct  638  MFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEIT-----------EENSGALDKVYN  686

Query  723  ETIAKVTDDYARRYTFNTAIAAVMELLNHVSKAEESSEQDRAVVQEALDAAVAMLAPIVP  782
            ET+  VT++  +   FNTAIA +M ++N  +K +        +  +   + V ++AP+ P
Sbjct  687  ETVKAVTEQVDQM-KFNTAIAQLMVFVNAANKEDK-------LFSDYAKGFVQLIAPFAP  738

Query  783  HICTVLWQSLGGLVNEERVDVVDADWPTADKSAMVQDEKLIIVQVNGKVRAKITVAADAS  842
            H+   LWQ+L +  + E +  V   WP+ D S +V+++  I+VQ++GKV+AK+ VA D S
Sbjct  739  HLGEELWQALTA--SGESISYV--PWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLS  794

Query  843  KDEVEKLAMADEHVQKFIADNTVRKVIVVPGKLVNIVTN  881
            ++E++ +A+A+E VQ  IA++ + KVI VP KLVNIV +
Sbjct  795  REELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

1063) leuS in NC_005835


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  547 bits (2064),  Expect = 1e-156, Method: Compositional matrix adjust.
 Identities = 380/879 (44%), Positives = 558/879 (64%), Gaps = 54/879 (6%)

Query  4    YNPHAIEAKWQRFWEEK-GFMKAKDLPGGRGKQYVLVMFPYPSG-DLHMGHLKNYTMGDV  61
            Y+  AIE+KWQ FW ++  F  + D  +++ K Y L MFPYPSG +LH+GH   YT  D+
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTD--ASKPKFYALDMFPYPSGAGLHVGHPEGYTATDI  61

Query  62   LARFRRMQGYEVLHPMGWDAFGLPAENAALKFGVHPKDWTYANIRQAKESLRLMGILYDW  121
            L+RF+R QG +VLHPMGWDAFGLPAE+ A+  G +P + T  NI + K  +  +G+ YDW
Sbjct  62   LSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDW  121

Query  122  DREVTTCEPEYYRWNQWIFLKMWEKGLAYRAKGLVNWCPKCQTVLANEQVVEGRCWRHED  181
            DREV T +P+YY+W QWIF K+ EKGLAY A   VNW     T +ANE+V+ +    + +
Sbjct  122  DREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGG  181

Query  182  TPVEKRELEQWYLRITAYAERLLKDLEGLNWPEKVKAMQRAWIGRSEGAEILFPVEGKEV  241
             PV ++ + QW L+ITAYAERLL DLE ++WPE +K MQR WIG+S GA++ F V + + 
Sbjct  182  YPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDK  241

Query  242  RIPVFTTRPDTLFGATFLVLAPEHPLTLELAAPEKREEVLAYVEAAKRKTEIERQAEGRE  301
             + VFTTRPDTLFGAT+ VLAPEH+L   ++++++ E V  Y   A  K+++ R   ++E
Sbjct  242  DFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKE  301

Query  302  KTGVFLGAYALNPATGERIPIWTADYVLFGYGTGAIMAVPAHDQRDYEFARKFGLPIKKV  361
            KTGV  G+YA+NP  G  +P+W ADYVL +YGTGAIMAVPAHD+RD EFA++F L I  V
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  362  IerpgeplpeplerAYEEPGIMVNSGPFDGTESEEGKRKVIAWLEEKGLGKGRVTYRLRD  421
            +E      +     A+ E G+ +NS+ +DG +   +  K++ WLE  G+G+  VTYRLRD
Sbjct  362  LEGGNVEEA-----AFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  422  WLISRQRYWGTPIPMVHCEACGvvpvpeeelpvllpdlkdvedIRPKGKSPLEAHPEFYE  481
            WL+SRQRYWG PIP++H E  G      E    L+  +         G SPL    +  E
Sbjct  417  WLFSRQRYWGEPIPIIHWED-GTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  482  TTCPKCGGPAKRdtdtmdtffdSSWYYLRYTDPHN-DRLPFDPEKANAWMPVDQYIGGVE  540
             T    G  ++R+T+TM    +SSWYYLRY DPHN ++L+ D E  + W+PVD Y+GG E
Sbjct  476  VTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLA-DEELLKQWLPVDIYVGGAE  533

Query  541  HAVLHLLYSRFFTKFLHDLGMVKVEEPFQGLFTQGMVLAWTDFGPVEVEGSVVRLPEPTR  600
            HAVLHLLY+RF  K L DLG+V   EPFQ LF QGM+L+ T +   +  G++V     + 
Sbjct  534  HAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILG-TSYR--DSRGALV-----AT  585

Query  601  IRLEIPESALSLEDVRKMGAELRPHEDGTLHLWKPAVMSKSKGNGVMVGPFVKEQGADIA  660
             ++E  ++++   +    G EL            PA MSKS  N V  +  V + GAD  
Sbjct  586  DKVEKRDGSFFHVET---GEELEQ---------APAKMSKSLKNVVNPDDVVEQYGADTL  633

Query  661  RITILFAAPPENEMVWTEEGVQGAWRFLNRIYRRVAEDREALLETSGVFQAEALEGKDRE  720
            R+  +F +P +  + W+EEG++G+++FL+R+YR ++  +E   E SG ++          
Sbjct  634  RVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLIT-TKEITEENSGALD---------K  683

Query  721  LYGKLHETLKKVTEDLEALRFNTAIAALMEFLNALYEYRKDRPVTPVYRTAIRYYLQMLF  780
            +Y   +ET+K VTE+++ ++FNTAIA LM F+NA     K+  + + Y  +   ++Q++ 
Sbjct  684  VY---NETVKAVTEQVDQMKFNTAIAQLMVFVNAA---NKEDKLFSDYAKG---FVQLIA  734

Query  781  PFAPHLAEELWHWF--WPDSLFEAGWPELDEKALEKDVVEVAVQVNGRVRGTIHIPKDAP  838
            PFAPHL+EELW+ +    +S+    WP  DE  L  + VE+ VQ++G+V++ + ++KD +
Sbjct  735  PFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLS  794

Query  839  LEVARAEALKVRNVRAHLEGKEVVKEIYVPGKILNLVVR  877
             E  +  AL   +V+A++ GK+++K I VP K++N+V++
Sbjct  795  REELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

1064) leuS in NC_009664


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  547 bits (2066),  Expect = 1e-156, Method: Compositional matrix adjust.
 Identities = 368/860 (43%), Positives = 546/860 (64%), Gaps = 71/860 (8%)

Query  33   YDAFALQEKWLPVWDERKPFRSGEPGDERPKKYVLDMFPYPSG-DLHMGHAEAYALGDVI  91
            YD  A++ KW + W +   F++G  +  +PK Y LDMFPYPSG +LH+GH+E+Y+  D++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTG-TDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDIL  62

Query  92   ARYWLQRGFDVMHPIGWDAFGLPAENAAIKRGLDPRRWTYDNIAQQRASMRRYACSFDWD  151
            +R+   +G +V+HP+GWDAFGLPAE+ A+  G DP   T +NIA+ +  +   + S+DWD
Sbjct  63   SRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWD  122

Query  152  RVLHTSDPEYYRWNQWLFLKLYEKGLAYRKDSLVNWDPVDQTVLANEQVLPDGTSERSGA  211
            R ++T+DP+YY+W QW+F KLYEKGLAY  +  VNW     T +ANE+VLPDGTSER+G 
Sbjct  123  REVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGY  182

Query  212  KVVKKKLTQWYFRITEYADRLLDDLDTLEGQWPAKVISMQRNWIGRSTGAEVEFAIEGRD  271
             VV+K + QW ++IT YA+RLL+DL+ ++  WP  +  MQRNWIG+STGA+V F + + D
Sbjct  183  PVVRKPMRQWMLKITAYAERLLEDLEEVD--WPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  272  EPVTVYTTRPDTLHGATFMVVaadsdlaeelaagaPDDVRAAFEAYRTQVQETSDIDRLS  331
               TV+TTRPDTL GAT+ V+A++  L + ++++   +   A   Y+ Q    SD+ R  
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAE---AVADYKRQASLKSDLARTD  297

Query  332  SEREKTGVPLGRYAVNPVNGERLPIWAADYVLADYGTGAIMAVPAHDQRDLDFARAFGLP  391
              +EKTGV  G YA+NPVNG  +P+W ADYVLA YGTGAIMAVPAHD+RD +FA+ F L 
Sbjct  298  LAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLD  357

Query  392  vrvvvdvrdddGNPLPDPAESGTATAGDGVLVNSGALDGLGKQAGIAKAIEDLTAAGKGR  451
            +             L +     +A + DG+ +NS+ LDGL+K ++IAK +E L A G G 
Sbjct  358  II----------PVLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGN  407

Query  452  AAKNYRLRDWLISRQRYWGTPIPVVH-TENGEVPVPEDQLPVLLPPSEGLNLTPKGTSPL  510
                YRLRDWL+SRQRYWG PIP++H  +    +VPE +LP++LP + ++  +  G SPL
Sbjct  408  ENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPL  467

Query  511  GAAEDWVNVPSPVDGSPARRDPDTMDTFVDSSWYFLRFVSPHDDTKAFDTDLIAQWGPVD  570
            +   DW++V    DG  +RR+ +TM    +SSWY+LR++ PH+  K  D +L+ QW PVD
Sbjct  468  ANVTDWLEVTRE-DGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVD  526

Query  571  QYVGGVTHAILHLLYARFITKVLHDLGYLPFDEPFTRLLNQGMV----------------  614
             YVGG  HA+LHLLYARF  KVL DLG +P  EPF +L+NQGM+                
Sbjct  527  IYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATD  586

Query  615  ------------------QMDGSAMSKSKGNIVRLSDQLEEHGVDAIRLTMAFAGPPEDD  656
                              +   + MSKS  N+V   D +E+ G D++R+   F GP +  
Sbjct  587  KVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  657  IDWADVSPSGSAKFLGRAWRL--ARDVTSEPGVDPTTGDAALRSVTHRTLHEVSQHVEAF  714
            I W++ +  GS KFL+R  RL  ++++T E +       +AL  V + T+  V+++V+  
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLITTKEITEENS-------GALDKVYNETVKAVTEQVDQM  699

Query  715  RFNVAVARLMELVNATRKAIDSGPGAGDPavreaveatavvLSLFAPYAAEDMW-SLLGH  773
            +FN A+A+LM +VNA+ K         D    +   +   +++ FAP  +E++W +L + 
Sbjct  700  KFNTAIAQLMVFVNAANKE--------DKLFSDYAKGFVQLIAPFAPHLGEELWQALTAS  751

Query  774  DPCVARAGWPAVDESLLvqdtvtcvvqvqGKVRDRLEVSPDITQDALRELALASEKVQAA  833
            +  ++   WP+ DES LV++ V  VVQ++GKV+ +L V+ D++++ L+E+ALA+EKVQA 
Sbjct  752  GESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAE  811

Query  834  LGGRDLRTVVVRAPKLVNIV  853
            ++G+D+  V+  + KLVNIV
Sbjct  812  IAGKDIIKVIAVPNKLVNIV  831

1065) DehalGT_0253 in NC_013890


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  547 bits (2064),  Expect = 1e-156, Method: Compositional matrix adjust.
 Identities = 351/849 (42%), Positives = 539/849 (64%), Gaps = 59/849 (6%)

Query  5    YNPQETEKKWQDKWAADRLYHASEDSPKPKWYSLTMFPYTSG-NLHIGHWYAEVPADCFA  63
            Y+    E KWQ  WA ++ + ++ D++KPK Y+L MFPY SG  LH+GH  +  ++D ++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYKRLRGFNVMRPVGFDSFGLPAENAAIKHNIHPRIWTLNNVENMRRQLKTIGAMFDWDR  123
            R+KR +G NV++P+G D+FGLPAE+ A+    +P   T +N+ N +RQ++++G  +DWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVITCLPEYYKWTQWFFLKLYEAGLAYRAKAPVNWCPSCQAVLANEQVV-DGTCWRCETP  182
            EV T  P+YYKWTQW+F KLYE GLAY A  PVNW     + +ANE+V+ DGT  R   P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  TTRRDLEQWFFRITNYADEL-KDHEGLDWPEKITAMQRNWVGKSYGAEVSFALDCPTAFE  241
              R+ + QW ++IT YA+ L  D E +DWPE I  MQRNW+GKS GA+V+F +      +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDT---D  240

Query  242  KEIKVFTTRPDTIYGVTFMVLAPEHPLVEKITTPENKAAVDAYIKKSRTCTEIERLSTER  301
            K++ VFTTRPDT++G T+ VLAPEH+LV+ ITT+++  AV  Y +++   +++ R    +
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  302  EKDGVFTGTYVTNRVNGQKVPVWIGDYVLQSYGTGAVMGVPAHDERDFVFAQKYHLPVIT  361
            EK GV TG+Y  N VNG+ +PVWI+DYVL SYGTGA+M+VPAHDERD  FA++++L +I 
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  362  VIAPSAYDGKPLEVAYINEGVMLNSGPFNGMPNTEGKEKVCDYLAEHGWGKKTVNYKLRD  421
            V+     +G+  E A+ ++G+ +NS+ ++G+ ++ +  K+ + L  +G G+  V Y+LRD
Sbjct  361  VLE----GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  422  WLISRQRYWGAPIPMVYCEKCGIVPVPEKDLPVLLPEDVEFRSG--GESPLKYNEGFVNT  479
            WL+SRQRYWG PIP++  E     +VPE +LP++LP   ++R++  GESPL    + ++ 
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE-  475

Query  480  ICPVCGGKAKRETDTMDTFMCSSWYFLRYTSPGYDKGPFDPVKLKYWMPVDLYTGGAEHA  539
            +    G K++RET+TM     SSWY+LRY  P       D   LK W+PVD+Y GGAEHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  540  VMHLFYSRFFTKALRDMGIIDFGEPFKKLFNQGIIVSN----------------------  577
            V+HL+Y+RF  K L D+G++   EPF+KLFNQG+I++                       
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSF  595

Query  578  ------------HQKMSKSKGNVVTPDNLVAEVGTDAVRAYLMFVGPWDQGGEWNDSGLS  625
                          KMSKS  NVV PD++V + G+D++R Y MF+GP D +  W++ GL 
Sbjct  596  FHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLE  655

Query  626  GMSRWLNRVWNLFTEEYTPQTASAEAERELKRTLHQTIKKITMDIERLRFNTVVAALMEL  685
            G  + L+RV  L+    T +  + E    L +  ++T+K +T ++++++FNT +A LM +
Sbjct  656  GSRKFLDRVYRLI----TTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVF  711

Query  686  SNSLAKLKETAAISAENWQNTLQTFALMLAPVAPHIAEELWANLGMK-YSIHNQNWPTWD  744
             N+  K             +  + F  ++AP APH++EELW  L     SI    WP+ D
Sbjct  712  VNAANK-------EDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYD  764

Query  745  EELAKDEVITLIIQVNGKLRERLEMPAGISEAEAKETALNSERVKPHLLGKTPVTVIYVP  804
            E    ++ + +++Q++GK++ +L ++ ++S  E +E AL +E+V++++ GK  + VI VP
Sbjct  765  ESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVP  824

Query  805  GKLVNIVVK  813
             KLVNIV+K
Sbjct  825  NKLVNIVIK  833

1066) leuS in NC_008601


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  547 bits (2065),  Expect = 1e-156, Method: Compositional matrix adjust.
 Identities = 356/859 (42%), Positives = 551/859 (65%), Gaps = 78/859 (9%)

Query  4    YNFSDIEKSTQDYWRKNDTFKTIEDNTKEKFYCLSMLPYPSGT-LHMGHVRNYTIGDVIA  62
            Y+ + IE   Q +W  N+TFKT  D +K KFY L M+PYPSG+ LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYQKMQGKNVLHPMGWDAFGLPAENAAIKHKKSPYEWTKSNIAYMRSQLDSLGFSFDWSR  122
            R+++ QG NVLHPMGWDAFGLPAE+ A+   + P E T  NIA  + Q+++LGFS+DW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EIATCDEDYYKWEQWFFIQLYKKGLAYRKNSVVNW-DPVDQTVLANEQVVDGRGWRSGAL  181
            E+ T D +YYKW QW+F +LY KGLAY  +  VNW + ++ ++  +E + DG + R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VEKKEIPQWFLKITDYADELLQDISKLDGWPEAVKTMQINWIGKSKGLTVKFKIKDSNQE  241
            V +K + QW LKIT YA+ LL+D+  +D WPE++K MQ NWIGKS G  V FK+KD++++
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  242  IEVFTTRPDTLMGVNYLGIAPEHPLALEEAKTNSKLAAFIEECKKTSTMEADLA----TQ  297
            + VFTTRPDTL G  Y  +APEH+L   +A T S  A  + + K+ +++ +DLA    ++
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALV--DAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  298  EKKGFKTSIKVIHPISAETIDVWVANFVLMGYGSGAVMSVPAHDQRDWEFAQKYNIPLKQ  357
            EK G  T+   I+P+++  + VW+A++VL +YG+GA+M+VPAHD+RDWEFA+++N+ +  
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  358  VIESNDKKLKIDLEKQAFTEKGILINSGEFDGLNFKNAYQAIKKYLTEQNKGYETTNFRI  417
            V+E+       ++E  AFTE G+ INS+ +DGL+  +A   +   L  +  G E   +R+
Sbjct  361  VLEGG------NVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRL  414

Query  418  HDWGISRQRYWGCPIPMIHCDDCGAVPEKEENLPVRLPTDVTLTEAG---SPLKDIPEFI  474
            +DW +SRQRYWG PIP+IH +D  + +  E +LP+ LP    +  +G   SPL ++ + +
Sbjct  415  RDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWL  474

Query  475  NVACPECGKPAKRETDTFDTFFESSWYYARYTCPTANQMLDQEA--NYWLPVDKYIGGIE  532
            +V+  +  K ++RET+T      SSWYY RY  P   + L +E   + WLPVD Y+GG E
Sbjct  475  EVTREDGVK-GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAE  533

Query  533  HAIMHLLYARFFHKLMRDQGLVKSDEPFKNLLTQGMVL-------------------KDG  573
            HA++HLLYARF HK++ D G+V + EPF++L+ QGM+L                   +DG
Sbjct  534  HAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDG  593

Query  574  ---------------AKMSKSKGNTVDPQELIDRYGADTVRLFSMFAAPPEQSLEWSETG  618
                           AKMSKS  N V+P++++++YGADT+R++ MF +P + S+ WSE G
Sbjct  594  SFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEG  653

Query  619  VEGANKFLRKVFNYAELNKDIFAKNITLESQKLTKEDKKARFEI--HSNLKQAIFDFDKS  676
            +EG+ KFL +V+               L + K   E++ + ++   +  +K    + D+ 
Sbjct  654  LEGSRKFLDRVYR--------------LITTKEITEENSGALDKVYNETVKAVTEQVDQM  699

Query  677  QFNTVVSACMKILNTLNNYDNL-SESVKVEGFSILLRILAPFTPHLCHYLWQQLNL-GED  734
            +FNT ++  M ++N+ N+ D+L S+  K  GF   ++++APF+PHL + LWQ L   GE 
Sbjct  700  KFNTAIAQLMVFVNAANKEDKLFSDYAK--GF---VQLIAPFAPHLGEELWQALTASGES  754

Query  735  ILHTSFPTVDNNALEKDEFLLVVQINGKLKAKLELDASLSPNQVEEIVLADQHVKSFIDN  794
            I   + P+ D++ L  ++  +VVQI+GK+KAKL +   LS ++++E+ LA++ V++ I  
Sbjct  755  ISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAG  814

Query  795  KQVVKVIYVPQKLINIVIK  813
            K+++KVI VP+KL+NIVIK
Sbjct  815  KDIIKVIAVPNKLVNIVIK  833

1067) UMN179_01479 in NC_015460


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  547 bits (2065),  Expect = 1e-156, Method: Compositional matrix adjust.
 Identities = 360/867 (42%), Positives = 571/867 (66%), Gaps = 48/867 (5%)

Query  5    YRPDLVESRIQKYWQDNKTFKVQPDPSKEKYYCLSMFPYPSGR-LHMGHVRNYTIGDVIS  63
            Y    +E++ Q +W DN TFK   D+SK K+Y L MFPYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMNGKNVLQPIGWDAFGLPAENAAIKNKAAPATWTYDNIEYMKNQLKMLGFSYDWDR  123
            R++R +G NVL+P+GWDAFGLPAE+ A+     PA  T +NI   K Q++ LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EIATCKPQYYKWEQWFFTELYKKGLIYKKTSTVNWCPNDQTVLANEQV-NDGCCWRCDTP  182
            E+ T  P+YYKW QW+FT LY KGL Y     VNW  +  T +ANE+V  DG   R + P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VEQKEIPQWFVKITDYAEQLLQGLDQLPEWPDQVKAMQRNWIGRSEGVEITFKMQDSDET  242
            V +K + QW +KIT YAE+LL++L+++ +WP+ +K MQRNWIG+S G ++TFK++D+D  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  VTVYTTRPDTFYGVSYLAVAAGHPLAEQAAKNNP--ELAQFIQECR-NTKVAEAELATME  299
             TV+TTRPDT++G +Y  +A+ H+L +  + ++    +A++ ++   ++ +A ++LA  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGMFTGRYALHPITGEAVPVWIANFVLMHYGTGAVMAVPAHDQRDYEFAQKYHLPLKPV  359
            K G+ TG YA++P+ G  +PVWIA++VL  YGTGA+MAVPAHD+RD EFA++++L + PV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  360  IAPLDGSELDLSKAAYTEHGVAINSAEFNGLDFEQAFNGIADKLEAMGVGKRQVNYRLRD  419
               L+G++++   AA+TE+G+ INS  ++GLD   A+  + + LEA GVG+ +V YRLRD
Sbjct  362  ---LEGGNVE--EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGTPIPMLTLENGdvvpvpladlpvelpedVVM---DGVQSPIKADPNWAKT  476
            W  SRQRYWG PIP++  E+G   +VP ++LP+ LP    +   +  +SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  TY-NGQPALRETDTFDTFMESSWYYARYTCPQYQQGMLNSEEANYWLPVDQYIGGIEHAT  535
            T  +G  + RET+T      SSWYY RY  P+  + + + E  + WLPVD Y+GG EHA 
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLLYFRFYHKLLRDAGLLACDEPATKLLCQGMVLADAFYYTSETNERIWVSPTKVTITR  595
            +HLLY RF HK+L D G+++  EP  KL+ QGM+L+ ++    ++   + V+  KV   R
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY---RDSRGAL-VATDKVE-KR  591

Query  596  DEKGRIIKAVDPEGHELVHAGMTKMSKSKNNGIDPQEMVEKYGADTVRLFMMFASPAEMT  655
            D  G ++      G+EL +A  +KMSKS +N ++P+++VE+YGADT+R++ MF +P + +
Sbjct  592  D--GSFFHV--ETGEELEQAP-AKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  656  LEWQESGVEGANRFLRRLWKLTYDYLQQPATVELDPKALSADQK-ALRRDLHKTIAKVSD  714
            + W E G+EG+ +FL R+ +L            +  K ++ ++  AL +  + T+  V++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRL------------ITTKEITEENSGALDKVYNETVKAVTE  694

Query  715  DIGRRQTFNTAIAAIMELMNKLTKAPLVQEQDRAVMKEALNAVIKMLYPITPHICFQLWQ  774
            ++++ + FNTAIA +M ++N   K       +  +  +  ++ ++++ P++PH+  +LWQ
Sbjct  695  QVDQMK-FNTAIAQLMVFVNAANK-------EDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  775  DL-GNEDDIDFAPWVVADQQAMVDEEKLVVVQVNGKVRGKITVAASASEEEIKTAAMADE  833
             L ++ + I + PW   D+  +V+++  +VVQ++GKV++K+ VA   S EE++  A+A+E
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  834  NVQKHLDGLNIVKVIYVPGKLLSFVAK  860
            +VQ ++ G +I+KVI VP KL+++V K
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVIK  833

1068) leuS in NC_021743


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  547 bits (2064),  Expect = 1e-156, Method: Compositional matrix adjust.
 Identities = 364/868 (42%), Positives = 571/868 (66%), Gaps = 50/868 (5%)

Query  5    YNPSEIEPKVQRYWAENKVFKAVKDVTKEKYYCLSMLPYPSGK-LHMGHVRNYTIGDVVS  63
            Y+ + IEPK Q +WA+N  FK+  D +K K+Y L M+PYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMIGKNVLQPMGWDAFGLPAEGAAVKNNTAPAKWTYENIEYMKGQLKMLGFSYDWDR  123
            R++R  G NVL+PMGWDAFGLPAE  A+     PA  T ENI   K Q++ LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVTTCRPEYYKWEQWFFTELYKKGLVYKKTSTVNWCPNDETVLANEQV-HEGCCWRCDTP  182
            EV T  P+YYKW QW+FT LY KGL Y     VNW  +  T +ANE+V  +G   R + P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VEQREIPQWFIKITDYAEELLNQLDNLPQWPDQVKTMQRNWIGRSEGVEITFKIAGSNVE  242
            V ++ + QW +KIT YAE LL++L+++ +WP+ +K MQRNWIG+S G ++TFK+ +++ +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LPVYTTRPDTFFGVSY--VaiaaahplaelaaQNNPALAEFIREAK-NTKVAEAELATME  299
            + V+TTRPDT+FG +Y  +A   A   A  ++++  A+A++ R+A  ++ +A ++LA  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGMATGLFAIHPLTGKEVPVWVANFVLMHYGTGAVMAVPAHDERDFEFAQKYDLQINQV  359
            K G+ TG +AI+P+ GKE+PVW+A++VL  YGTGA+MAVPAHDERD EFA++++L+I   
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDI---  358

Query  360  IQPLDGSEWDFSKAAYTEHGKLINSAEFDGLEFDVAFTAIADKLEAMGVGKRQVNFRLRD  419
            I  L+G+  +   AA+TE+G  INS  +DGL+   A++ + + LEA GVG+ +V +RLRD
Sbjct  359  IPVLEGG--NVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMMTTEEGEVVTVPLQDLPVILP--EDVVMNGV-QSPIKADPEWAKT  476
            W  SRQRYWG PIP++  E+G   +VP  +LP++LP   D+  +G  +SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  TY-NGKPALRETDTFDTFMESSWYYARYTCPQYHEGMLDSDEANYWLPVDQYIGGIEHAT  535
            T  +G  + RET+T      SSWYY RY  P+  E + D +  + WLPVD Y+GG EHA 
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLLYFRFFHKLLRDAGILNSDEPATKLLCQGMVLADAFYYTSPTNERIWVSPTQVTLER  595
            +HLLY RF HK+L D G++ + EP  KL+ QGM+L+ ++      + R     + V+ ++
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSR----GALVATDK  587

Query  596  DEK--GRIIKATDPQGRELVHSGMTKMSKSKNNGIDPQEMVEKYGADTVRLFMMFASPAE  653
             EK  G ++      G EL ++  +KMSKS +N ++P+++VE+YGADT+R++ MF +P +
Sbjct  588  VEKRDGSFFHVET--GEELEQAP-AKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLD  644

Query  654  MTLEWQESGVEGAKRFLGRVWNLVYSYAQNPATTALDVNALDKDQKELRRDVHKTIAKVS  713
             ++ W E G+EG+++FL+R    VY        T  +  ALDK  +E       T+  V+
Sbjct  645  ASIAWSEEGLEGSRKFLDR----VYRLITTKEITEENSGALDKVYNE-------TVKAVT  693

Query  714  DDIGRRQTFNTAIAAVMELMNKLTKAPLETEQDKAVMAEALSAVVRMLYPITPHICFELW  773
            +++++ + FNTAIA +M ++N        ++++  + ++   + V+++ P++PH+  ELW
Sbjct  694  EQVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELW  745

Query  774  QVL-GNEQTIDFAPWVQADESAMVEDEKLVVVQVNGKVRGKITVSATATEDEVKAIAKAD  832
            Q L ++ ++I + PW   DES +VE++  +VVQ++GKV++K+ V+   + +E++ +A A+
Sbjct  746  QALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALAN  805

Query  833  PNVAKFLDGQQIVKEIYVPFKMLSFAVK  860
             +V   + G++I+K I VP K++++ +K
Sbjct  806  EKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

1069) leuS in NC_021739


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  547 bits (2064),  Expect = 1e-156, Method: Compositional matrix adjust.
 Identities = 364/868 (42%), Positives = 571/868 (66%), Gaps = 50/868 (5%)

Query  5    YNPSEIEPKVQRYWAENKVFKAVKDVTKEKYYCLSMLPYPSGK-LHMGHVRNYTIGDVVS  63
            Y+ + IEPK Q +WA+N  FK+  D +K K+Y L M+PYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMIGKNVLQPMGWDAFGLPAEGAAVKNNTAPAKWTYENIEYMKGQLKMLGFSYDWDR  123
            R++R  G NVL+PMGWDAFGLPAE  A+     PA  T ENI   K Q++ LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVTTCRPEYYKWEQWFFTELYKKGLVYKKTSTVNWCPNDETVLANEQV-HEGCCWRCDTP  182
            EV T  P+YYKW QW+FT LY KGL Y     VNW  +  T +ANE+V  +G   R + P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VEQREIPQWFIKITDYAEELLNQLDNLPQWPDQVKTMQRNWIGRSEGVEITFKIAGSNVE  242
            V ++ + QW +KIT YAE LL++L+++ +WP+ +K MQRNWIG+S G ++TFK+ +++ +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LPVYTTRPDTFFGVSY--VaiaaahplaelaaQNNPALAEFIREAK-NTKVAEAELATME  299
            + V+TTRPDT+FG +Y  +A   A   A  ++++  A+A++ R+A  ++ +A ++LA  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGMATGLFAIHPLTGKEVPVWVANFVLMHYGTGAVMAVPAHDERDFEFAQKYDLQINQV  359
            K G+ TG +AI+P+ GKE+PVW+A++VL  YGTGA+MAVPAHDERD EFA++++L+I   
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDI---  358

Query  360  IQPLDGSEWDFSKAAYTEHGKLINSAEFDGLEFDVAFTAIADKLEAMGVGKRQVNFRLRD  419
            I  L+G+  +   AA+TE+G  INS  +DGL+   A++ + + LEA GVG+ +V +RLRD
Sbjct  359  IPVLEGG--NVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMMTTEEGEVVTVPLQDLPVILP--EDVVMNGV-QSPIKADPEWAKT  476
            W  SRQRYWG PIP++  E+G   +VP  +LP++LP   D+  +G  +SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  TY-NGKPALRETDTFDTFMESSWYYARYTCPQYHEGMLDSDEANYWLPVDQYIGGIEHAT  535
            T  +G  + RET+T      SSWYY RY  P+  E + D +  + WLPVD Y+GG EHA 
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLLYFRFFHKLLRDAGILNSDEPATKLLCQGMVLADAFYYTSPTNERIWVSPTQVTLER  595
            +HLLY RF HK+L D G++ + EP  KL+ QGM+L+ ++      + R     + V+ ++
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSR----GALVATDK  587

Query  596  DEK--GRIIKATDPQGRELVHSGMTKMSKSKNNGIDPQEMVEKYGADTVRLFMMFASPAE  653
             EK  G ++      G EL ++  +KMSKS +N ++P+++VE+YGADT+R++ MF +P +
Sbjct  588  VEKRDGSFFHVET--GEELEQAP-AKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLD  644

Query  654  MTLEWQESGVEGAKRFLGRVWNLVYSYAQNPATTALDVNALDKDQKELRRDVHKTIAKVS  713
             ++ W E G+EG+++FL+R    VY        T  +  ALDK  +E       T+  V+
Sbjct  645  ASIAWSEEGLEGSRKFLDR----VYRLITTKEITEENSGALDKVYNE-------TVKAVT  693

Query  714  DDIGRRQTFNTAIAAVMELMNKLTKAPLETEQDKAVMAEALSAVVRMLYPITPHICFELW  773
            +++++ + FNTAIA +M ++N        ++++  + ++   + V+++ P++PH+  ELW
Sbjct  694  EQVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELW  745

Query  774  QVL-GNEQTIDFAPWVQADESAMVEDEKLVVVQVNGKVRGKITVSATATEDEVKAIAKAD  832
            Q L ++ ++I + PW   DES +VE++  +VVQ++GKV++K+ V+   + +E++ +A A+
Sbjct  746  QALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALAN  805

Query  833  PNVAKFLDGQQIVKEIYVPFKMLSFAVK  860
             +V   + G++I+K I VP K++++ +K
Sbjct  806  EKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

1070) leuS in NC_021082


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  547 bits (2064),  Expect = 1e-156, Method: Compositional matrix adjust.
 Identities = 364/868 (42%), Positives = 571/868 (66%), Gaps = 50/868 (5%)

Query  5    YNPSEIEPKVQRYWAENKVFKAVKDVTKEKYYCLSMLPYPSGK-LHMGHVRNYTIGDVVS  63
            Y+ + IEPK Q +WA+N  FK+  D +K K+Y L M+PYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMIGKNVLQPMGWDAFGLPAEGAAVKNNTAPAKWTYENIEYMKGQLKMLGFSYDWDR  123
            R++R  G NVL+PMGWDAFGLPAE  A+     PA  T ENI   K Q++ LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVTTCRPEYYKWEQWFFTELYKKGLVYKKTSTVNWCPNDETVLANEQV-HEGCCWRCDTP  182
            EV T  P+YYKW QW+FT LY KGL Y     VNW  +  T +ANE+V  +G   R + P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VEQREIPQWFIKITDYAEELLNQLDNLPQWPDQVKTMQRNWIGRSEGVEITFKIAGSNVE  242
            V ++ + QW +KIT YAE LL++L+++ +WP+ +K MQRNWIG+S G ++TFK+ +++ +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LPVYTTRPDTFFGVSY--VaiaaahplaelaaQNNPALAEFIREAK-NTKVAEAELATME  299
            + V+TTRPDT+FG +Y  +A   A   A  ++++  A+A++ R+A  ++ +A ++LA  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGMATGLFAIHPLTGKEVPVWVANFVLMHYGTGAVMAVPAHDERDFEFAQKYDLQINQV  359
            K G+ TG +AI+P+ GKE+PVW+A++VL  YGTGA+MAVPAHDERD EFA++++L+I   
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDI---  358

Query  360  IQPLDGSEWDFSKAAYTEHGKLINSAEFDGLEFDVAFTAIADKLEAMGVGKRQVNFRLRD  419
            I  L+G+  +   AA+TE+G  INS  +DGL+   A++ + + LEA GVG+ +V +RLRD
Sbjct  359  IPVLEGG--NVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMMTTEEGEVVTVPLQDLPVILP--EDVVMNGV-QSPIKADPEWAKT  476
            W  SRQRYWG PIP++  E+G   +VP  +LP++LP   D+  +G  +SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  TY-NGKPALRETDTFDTFMESSWYYARYTCPQYHEGMLDSDEANYWLPVDQYIGGIEHAT  535
            T  +G  + RET+T      SSWYY RY  P+  E + D +  + WLPVD Y+GG EHA 
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLLYFRFFHKLLRDAGILNSDEPATKLLCQGMVLADAFYYTSPTNERIWVSPTQVTLER  595
            +HLLY RF HK+L D G++ + EP  KL+ QGM+L+ ++      + R     + V+ ++
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSR----GALVATDK  587

Query  596  DEK--GRIIKATDPQGRELVHSGMTKMSKSKNNGIDPQEMVEKYGADTVRLFMMFASPAE  653
             EK  G ++      G EL ++  +KMSKS +N ++P+++VE+YGADT+R++ MF +P +
Sbjct  588  VEKRDGSFFHVET--GEELEQAP-AKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLD  644

Query  654  MTLEWQESGVEGAKRFLGRVWNLVYSYAQNPATTALDVNALDKDQKELRRDVHKTIAKVS  713
             ++ W E G+EG+++FL+R    VY        T  +  ALDK  +E       T+  V+
Sbjct  645  ASIAWSEEGLEGSRKFLDR----VYRLITTKEITEENSGALDKVYNE-------TVKAVT  693

Query  714  DDIGRRQTFNTAIAAVMELMNKLTKAPLETEQDKAVMAEALSAVVRMLYPITPHICFELW  773
            +++++ + FNTAIA +M ++N        ++++  + ++   + V+++ P++PH+  ELW
Sbjct  694  EQVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELW  745

Query  774  QVL-GNEQTIDFAPWVQADESAMVEDEKLVVVQVNGKVRGKITVSATATEDEVKAIAKAD  832
            Q L ++ ++I + PW   DES +VE++  +VVQ++GKV++K+ V+   + +E++ +A A+
Sbjct  746  QALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALAN  805

Query  833  PNVAKFLDGQQIVKEIYVPFKMLSFAVK  860
             +V   + G++I+K I VP K++++ +K
Sbjct  806  EKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

1071) D648_9870 in NC_020834


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  547 bits (2064),  Expect = 1e-156, Method: Compositional matrix adjust.
 Identities = 364/868 (42%), Positives = 571/868 (66%), Gaps = 50/868 (5%)

Query  5    YNPSEIEPKVQRYWAENKVFKAVKDVTKEKYYCLSMLPYPSGK-LHMGHVRNYTIGDVVS  63
            Y+ + IEPK Q +WA+N  FK+  D +K K+Y L M+PYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMIGKNVLQPMGWDAFGLPAEGAAVKNNTAPAKWTYENIEYMKGQLKMLGFSYDWDR  123
            R++R  G NVL+PMGWDAFGLPAE  A+     PA  T ENI   K Q++ LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVTTCRPEYYKWEQWFFTELYKKGLVYKKTSTVNWCPNDETVLANEQV-HEGCCWRCDTP  182
            EV T  P+YYKW QW+FT LY KGL Y     VNW  +  T +ANE+V  +G   R + P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VEQREIPQWFIKITDYAEELLNQLDNLPQWPDQVKTMQRNWIGRSEGVEITFKIAGSNVE  242
            V ++ + QW +KIT YAE LL++L+++ +WP+ +K MQRNWIG+S G ++TFK+ +++ +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LPVYTTRPDTFFGVSY--VaiaaahplaelaaQNNPALAEFIREAK-NTKVAEAELATME  299
            + V+TTRPDT+FG +Y  +A   A   A  ++++  A+A++ R+A  ++ +A ++LA  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGMATGLFAIHPLTGKEVPVWVANFVLMHYGTGAVMAVPAHDERDFEFAQKYDLQINQV  359
            K G+ TG +AI+P+ GKE+PVW+A++VL  YGTGA+MAVPAHDERD EFA++++L+I   
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDI---  358

Query  360  IQPLDGSEWDFSKAAYTEHGKLINSAEFDGLEFDVAFTAIADKLEAMGVGKRQVNFRLRD  419
            I  L+G+  +   AA+TE+G  INS  +DGL+   A++ + + LEA GVG+ +V +RLRD
Sbjct  359  IPVLEGG--NVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMMTTEEGEVVTVPLQDLPVILP--EDVVMNGV-QSPIKADPEWAKT  476
            W  SRQRYWG PIP++  E+G   +VP  +LP++LP   D+  +G  +SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  TY-NGKPALRETDTFDTFMESSWYYARYTCPQYHEGMLDSDEANYWLPVDQYIGGIEHAT  535
            T  +G  + RET+T      SSWYY RY  P+  E + D +  + WLPVD Y+GG EHA 
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLLYFRFFHKLLRDAGILNSDEPATKLLCQGMVLADAFYYTSPTNERIWVSPTQVTLER  595
            +HLLY RF HK+L D G++ + EP  KL+ QGM+L+ ++      + R     + V+ ++
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSR----GALVATDK  587

Query  596  DEK--GRIIKATDPQGRELVHSGMTKMSKSKNNGIDPQEMVEKYGADTVRLFMMFASPAE  653
             EK  G ++      G EL ++  +KMSKS +N ++P+++VE+YGADT+R++ MF +P +
Sbjct  588  VEKRDGSFFHVET--GEELEQAP-AKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLD  644

Query  654  MTLEWQESGVEGAKRFLGRVWNLVYSYAQNPATTALDVNALDKDQKELRRDVHKTIAKVS  713
             ++ W E G+EG+++FL+R    VY        T  +  ALDK  +E       T+  V+
Sbjct  645  ASIAWSEEGLEGSRKFLDR----VYRLITTKEITEENSGALDKVYNE-------TVKAVT  693

Query  714  DDIGRRQTFNTAIAAVMELMNKLTKAPLETEQDKAVMAEALSAVVRMLYPITPHICFELW  773
            +++++ + FNTAIA +M ++N        ++++  + ++   + V+++ P++PH+  ELW
Sbjct  694  EQVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELW  745

Query  774  QVL-GNEQTIDFAPWVQADESAMVEDEKLVVVQVNGKVRGKITVSATATEDEVKAIAKAD  832
            Q L ++ ++I + PW   DES +VE++  +VVQ++GKV++K+ V+   + +E++ +A A+
Sbjct  746  QALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALAN  805

Query  833  PNVAKFLDGQQIVKEIYVPFKMLSFAVK  860
             +V   + G++I+K I VP K++++ +K
Sbjct  806  EKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

1072) D650_17700 in NC_020833


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  547 bits (2064),  Expect = 1e-156, Method: Compositional matrix adjust.
 Identities = 364/868 (42%), Positives = 571/868 (66%), Gaps = 50/868 (5%)

Query  5    YNPSEIEPKVQRYWAENKVFKAVKDVTKEKYYCLSMLPYPSGK-LHMGHVRNYTIGDVVS  63
            Y+ + IEPK Q +WA+N  FK+  D +K K+Y L M+PYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMIGKNVLQPMGWDAFGLPAEGAAVKNNTAPAKWTYENIEYMKGQLKMLGFSYDWDR  123
            R++R  G NVL+PMGWDAFGLPAE  A+     PA  T ENI   K Q++ LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVTTCRPEYYKWEQWFFTELYKKGLVYKKTSTVNWCPNDETVLANEQV-HEGCCWRCDTP  182
            EV T  P+YYKW QW+FT LY KGL Y     VNW  +  T +ANE+V  +G   R + P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VEQREIPQWFIKITDYAEELLNQLDNLPQWPDQVKTMQRNWIGRSEGVEITFKIAGSNVE  242
            V ++ + QW +KIT YAE LL++L+++ +WP+ +K MQRNWIG+S G ++TFK+ +++ +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LPVYTTRPDTFFGVSY--VaiaaahplaelaaQNNPALAEFIREAK-NTKVAEAELATME  299
            + V+TTRPDT+FG +Y  +A   A   A  ++++  A+A++ R+A  ++ +A ++LA  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGMATGLFAIHPLTGKEVPVWVANFVLMHYGTGAVMAVPAHDERDFEFAQKYDLQINQV  359
            K G+ TG +AI+P+ GKE+PVW+A++VL  YGTGA+MAVPAHDERD EFA++++L+I   
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDI---  358

Query  360  IQPLDGSEWDFSKAAYTEHGKLINSAEFDGLEFDVAFTAIADKLEAMGVGKRQVNFRLRD  419
            I  L+G+  +   AA+TE+G  INS  +DGL+   A++ + + LEA GVG+ +V +RLRD
Sbjct  359  IPVLEGG--NVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMMTTEEGEVVTVPLQDLPVILP--EDVVMNGV-QSPIKADPEWAKT  476
            W  SRQRYWG PIP++  E+G   +VP  +LP++LP   D+  +G  +SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  TY-NGKPALRETDTFDTFMESSWYYARYTCPQYHEGMLDSDEANYWLPVDQYIGGIEHAT  535
            T  +G  + RET+T      SSWYY RY  P+  E + D +  + WLPVD Y+GG EHA 
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLLYFRFFHKLLRDAGILNSDEPATKLLCQGMVLADAFYYTSPTNERIWVSPTQVTLER  595
            +HLLY RF HK+L D G++ + EP  KL+ QGM+L+ ++      + R     + V+ ++
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSR----GALVATDK  587

Query  596  DEK--GRIIKATDPQGRELVHSGMTKMSKSKNNGIDPQEMVEKYGADTVRLFMMFASPAE  653
             EK  G ++      G EL ++  +KMSKS +N ++P+++VE+YGADT+R++ MF +P +
Sbjct  588  VEKRDGSFFHVET--GEELEQAP-AKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLD  644

Query  654  MTLEWQESGVEGAKRFLGRVWNLVYSYAQNPATTALDVNALDKDQKELRRDVHKTIAKVS  713
             ++ W E G+EG+++FL+R    VY        T  +  ALDK  +E       T+  V+
Sbjct  645  ASIAWSEEGLEGSRKFLDR----VYRLITTKEITEENSGALDKVYNE-------TVKAVT  693

Query  714  DDIGRRQTFNTAIAAVMELMNKLTKAPLETEQDKAVMAEALSAVVRMLYPITPHICFELW  773
            +++++ + FNTAIA +M ++N        ++++  + ++   + V+++ P++PH+  ELW
Sbjct  694  EQVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELW  745

Query  774  QVL-GNEQTIDFAPWVQADESAMVEDEKLVVVQVNGKVRGKITVSATATEDEVKAIAKAD  832
            Q L ++ ++I + PW   DES +VE++  +VVQ++GKV++K+ V+   + +E++ +A A+
Sbjct  746  QALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALAN  805

Query  833  PNVAKFLDGQQIVKEIYVPFKMLSFAVK  860
             +V   + G++I+K I VP K++++ +K
Sbjct  806  EKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

1073) leuS in NC_021883


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  547 bits (2064),  Expect = 1e-156, Method: Compositional matrix adjust.
 Identities = 364/868 (42%), Positives = 571/868 (66%), Gaps = 50/868 (5%)

Query  5    YNPSEIEPKVQRYWAENKVFKAVKDVTKEKYYCLSMLPYPSGK-LHMGHVRNYTIGDVVS  63
            Y+ + IEPK Q +WA+N  FK+  D +K K+Y L M+PYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMIGKNVLQPMGWDAFGLPAEGAAVKNNTAPAKWTYENIEYMKGQLKMLGFSYDWDR  123
            R++R  G NVL+PMGWDAFGLPAE  A+     PA  T ENI   K Q++ LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVTTCRPEYYKWEQWFFTELYKKGLVYKKTSTVNWCPNDETVLANEQV-HEGCCWRCDTP  182
            EV T  P+YYKW QW+FT LY KGL Y     VNW  +  T +ANE+V  +G   R + P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VEQREIPQWFIKITDYAEELLNQLDNLPQWPDQVKTMQRNWIGRSEGVEITFKIAGSNVE  242
            V ++ + QW +KIT YAE LL++L+++ +WP+ +K MQRNWIG+S G ++TFK+ +++ +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LPVYTTRPDTFFGVSY--VaiaaahplaelaaQNNPALAEFIREAK-NTKVAEAELATME  299
            + V+TTRPDT+FG +Y  +A   A   A  ++++  A+A++ R+A  ++ +A ++LA  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGMATGLFAIHPLTGKEVPVWVANFVLMHYGTGAVMAVPAHDERDFEFAQKYDLQINQV  359
            K G+ TG +AI+P+ GKE+PVW+A++VL  YGTGA+MAVPAHDERD EFA++++L+I   
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDI---  358

Query  360  IQPLDGSEWDFSKAAYTEHGKLINSAEFDGLEFDVAFTAIADKLEAMGVGKRQVNFRLRD  419
            I  L+G+  +   AA+TE+G  INS  +DGL+   A++ + + LEA GVG+ +V +RLRD
Sbjct  359  IPVLEGG--NVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMMTTEEGEVVTVPLQDLPVILP--EDVVMNGV-QSPIKADPEWAKT  476
            W  SRQRYWG PIP++  E+G   +VP  +LP++LP   D+  +G  +SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  TY-NGKPALRETDTFDTFMESSWYYARYTCPQYHEGMLDSDEANYWLPVDQYIGGIEHAT  535
            T  +G  + RET+T      SSWYY RY  P+  E + D +  + WLPVD Y+GG EHA 
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLLYFRFFHKLLRDAGILNSDEPATKLLCQGMVLADAFYYTSPTNERIWVSPTQVTLER  595
            +HLLY RF HK+L D G++ + EP  KL+ QGM+L+ ++      + R     + V+ ++
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSR----GALVATDK  587

Query  596  DEK--GRIIKATDPQGRELVHSGMTKMSKSKNNGIDPQEMVEKYGADTVRLFMMFASPAE  653
             EK  G ++      G EL ++  +KMSKS +N ++P+++VE+YGADT+R++ MF +P +
Sbjct  588  VEKRDGSFFHVET--GEELEQAP-AKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLD  644

Query  654  MTLEWQESGVEGAKRFLGRVWNLVYSYAQNPATTALDVNALDKDQKELRRDVHKTIAKVS  713
             ++ W E G+EG+++FL+R    VY        T  +  ALDK  +E       T+  V+
Sbjct  645  ASIAWSEEGLEGSRKFLDR----VYRLITTKEITEENSGALDKVYNE-------TVKAVT  693

Query  714  DDIGRRQTFNTAIAAVMELMNKLTKAPLETEQDKAVMAEALSAVVRMLYPITPHICFELW  773
            +++++ + FNTAIA +M ++N        ++++  + ++   + V+++ P++PH+  ELW
Sbjct  694  EQVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELW  745

Query  774  QVL-GNEQTIDFAPWVQADESAMVEDEKLVVVQVNGKVRGKITVSATATEDEVKAIAKAD  832
            Q L ++ ++I + PW   DES +VE++  +VVQ++GKV++K+ V+   + +E++ +A A+
Sbjct  746  QALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALAN  805

Query  833  PNVAKFLDGQQIVKEIYVPFKMLSFAVK  860
             +V   + G++I+K I VP K++++ +K
Sbjct  806  EKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

1074) leuS in NC_003869


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  547 bits (2063),  Expect = 2e-156, Method: Compositional matrix adjust.
 Identities = 395/849 (47%), Positives = 551/849 (65%), Gaps = 59/849 (6%)

Query  8    VEIDRKWQKIWEETKLYKFNPENVDKKLYCLEMFPYPSGAKLHIGHWYNYGPTDSWARMK  67
              I+ KWQ +W +   +K   +    K+Y L+MFPYPSGA LH+GH   Y +TD  +R K
Sbjct  7    TAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSRFK  66

Query  68   RMQGYEVFHPMGFDAFGLPAENYAIKTGIHPYDSTMENIRTMERQLREMGVTFDWDYEII  127
            R QG +V+HPMG DAFGLPAE+YA+ TG +P + T ENI    RQ+  +G ++DWD E+ 
Sbjct  67   RAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDREVN  126

Query  128  TCLPEYYKWTQWIFLKLYEAGLAYRKKAPVNWCPSCQTVLANEQVI-DGKCERCGTEVTK  186
            T  P+YYKWTQWIF KLYE GLAY    PVNW     T +ANE+V+ DG  ER G  V +
Sbjct  127  TTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVR  186

Query  187  KELTQWFFKITAYAeelleklddldWPEKTKMMQRNWIGKSEGAEIEFKIDGKDLSFRVF  246
            K + QW +KITAYAE LLE L+++DWPE  K MQRNWIGKS GA++ FK+ + D  F VF
Sbjct  187  KPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVF  246

Query  247  TTRADTLFGATYVVLAPEHELVDLITTeeykeaveeykeyakkQSEIERLSTEKEKTGVF  306
            TTR+DTLFGATY VLAPEH LVD ITT +  EAV +YK  A  +S++ R    KEKTGV 
Sbjct  247  TTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVW  306

Query  307  TGAYAIHPLTGEKLPIWIADYVLVTYGTGCVMGVPGHDERDYEFATKYNLPIKRVIKGVG  366
            TG+YAI+P+ G  +P+WIADYVL +YGTG +M+VP+HDERD EFA ++NL I  V+ G G
Sbjct  307  TGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEG-G  365

Query  367  DVDDSLPFVEYGILVNSEEFTGMTSEEARVKIVEKLKAEGKAEFKVNYRMRDWLVSRQRY  426
            +V+++ +F E G+ +NS+ + G+    A  K+VE L AEG ++ +V YR+RDWL SRQRY
Sbjct  366  NVEEA-AFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRY  424

Query  427  WGAPIPIIHCERCGIvpvpeedlpvllpYDVEFEP--TGESPLKKHAGFMNVTCPKCGGP  484
            WG PIPIIH E     +VPE +LP++LP   ++ P  TGESPL + ++ ++VT    G  
Sbjct  425  WGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED-GVK  483

Query  485  ALRDPDTLDTFVDSSWYYLRYPDNKNDKEPFNKEWINKMLPVDKYVGGAEHATMHLLYSR  544
            + R+ +T+    +SSWYYLRY D  N     + E +++ LPVD YVGGAEHA +HLLY+R
Sbjct  484  GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYAR  543

Query  545  FITKVLRDLGYLNFDEPFLSLVHQGTILGP------------------------------  574
            F  KVL DLG +   EPF  L +QG ILG                               
Sbjct  544  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEE  603

Query  575  ---DGSRMSKSRGNVISPDDYIKQYGSDVFRLYLMFGFSYSEGGPWSDEGIKAIARFVNR  631
                 ++MSKS  NV++PDD + QYG+D +R+Y MF  +   + +WS+EG+ +  +F++R
Sbjct  604  LEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR  663

Query  632  VERFIEKFIETRQNPGKTKEEMEDAEKELNYVRHYTIKHVTLDADKFEFNTAIARIMELV  691
            V R+I            TKE  E+    L+ V + T+K VT + D+  FNTAIA++M +V
Sbjct  664  VYRLI-----------TTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFV  712

Query  692  NALYKYENEVEVKNMKFYEDVVRDFVKILAPFAPHFSEEMWERLGYEYSVFN-QKWPEWD  750
            NA          K+ K++ D  ++FV+++APFAPH++EE+W+ L      ++   WP  D
Sbjct  713  NA--------ANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYD  764

Query  751  EKALERDMIEIAIQVNGKVRSKAQVPSNATDEELKQIALSDERVKSYLDGKEIKKVIIVK  810
            E  L  + +EI +Q++GKV++K  V+ + + EEL+++AL++E+V++ + GK+I KVI V 
Sbjct  765  ESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVP  824

Query  811  NRLVNIVVN  819
            N+LVNIV++
Sbjct  825  NKLVNIVIK  833

1075) FN1517 in NC_003454


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  547 bits (2063),  Expect = 2e-156, Method: Compositional matrix adjust.
 Identities = 346/848 (41%), Positives = 540/848 (64%), Gaps = 50/848 (5%)

Query  4    YEFKEIEKKWQERWSKDNIFKTENQVEGKENYYVLSMLPYPSGK-LHVGHARNYTIGDVI  62
            Y+   IE KWQ  W+ ++ FKT  +  +K ++Y L M+PYPSG  LHVGH+  YT  D++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTD-ASKPKFYALDMFPYPSGAGLHVGHPEGYTATDIL  62

Query  63   SRYKRMKGYNVLQPMGWDSFGLPAENAAIQNGTHPAIWTKSNIENMRRQLKLMGFSYDWE  122
            SR+KR +G NVL+PMGWD+FGLPAE+ A++ G +PA  T  NI N +RQ++ +GFSYDW+
Sbjct  63   SRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWD  122

Query  123  REIASYTPEYYKWNQWLFKRMYEKGLIYKKKSLVNWCPDCQTVLANEQV-EDGMCWRHSK  181
            RE+ +  P+YYKW QW+F ++YEKGL Y     VNW  +  T +ANE+V  DG    ++ 
Sbjct  123  REVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTS-ERGG  181

Query  182  THVIQKELEQWFFKITDYADELLEGHEEIKDGWPEKVLTMQKNWIGKSFGTELKLKVVET  241
              V++K + QW +KIT YA+ LLE+ EE+  +WPE +  MQ+NWIGKS G+++ +KV +T
Sbjct  182  YPVVRKPMRQWMLKITAYAERLLEDLEEV--DWPESIKDMQRNWIGKSTGANVTFKVKDT  239

Query  242  GEDLPIFTTRIDTIYGVSYAVVAPEHPIVEKILKDNPSIKDKVTEMKNTDI----IERGA  297
            + D+ +FTTR DT++G +YAV+APEH++V+ I   + +  + V++ K        + R  
Sbjct  240  DKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQA--EAVADYKRQASLKSDLARTD  297

Query  298  EGREKNGIDSGWHIENPVNKEIVPLWIADYVLMNYGTGAVMGVPAHDERDFVFAGKYNLP  357
             ++EK G+ +G    NPVN   +P+WIADYVL +YGTGA+M+VPAHDERD  FA ++NL 
Sbjct  298  LAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLD  357

Query  358  VKQVITSKKSDEKVQLPYIEEGVMINSGEFNGLSSKDALVKIAEYVEEKGYGKRTYKYRL  417
            +  V+ + + +E    ++ E+G+ INS+ ++GL    A+ K+ E +E  G G+    YRL
Sbjct  358  IIPVLEGGNVEEA---AFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRL  414

Query  418  KDWGISRQRYWGTPIPALYCEKCGEVLEKDENLPVLLPDDIEFSGNG---NPLETSNKFK  474
            +DW +SRQRYWG PIP +  E        + +LP++LP   ++  +G   +PL       
Sbjct  415  RDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWL  474

Query  475  EATCPCCGGKARRDTDTMDTFVDSSWYFLRYCDPKNLNLPFSKEIVDKWTPVDQYIGGVE  534
            E T    G K+RR+T+TM    +SSWY+LRY DP N +     E++ +W PVD Y+GG E
Sbjct  475  EVTRE-DGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAE  533

Query  535  HAVMHLLYARFFHKVLRDLGLLSSNEPFKRLLTQGMVLGPSYYSEKENKYLLQKAAIIKG  594
            HAV+HLLYARF HKVL DLG+++++EPF++L+ QGM+LG SY   +    L+    + K 
Sbjct  534  HAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGA--LVATDKVEKR  591

Query  595  DKAY--SQSGEELQVKVEKMSKSKNNGVDPEEMLDKYGADTTRLFIMFAAPPEKELEWNE  652
            D ++   ++GEEL+    KMSKS +N V+P++++++YGADT R++ MF +P +  + W+E
Sbjct  592  DGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSE  651

Query  653  NGLAGAYRFLTRVWRLVFENSELVKNANDEIDYNKLSKEDKTLLIKL-NQTIKKVTDAIE  711
            +GL G+ +FL RV RL              I  + ++ E+   L K+ N+T+K VT+ ++
Sbjct  652  EGLEGSRKFLDRVYRL--------------ITTKEITEENSGALDKVYNETVKAVTEQVD  697

Query  712  NNYHFNTAIAANMELINEVQTYVSSSMNSEQAAKILGYTLKKIIIMLSPFVPHFCDEIWE  771
            +   FNTAIA  M ++N           +++  K+++   K ++ +++PF PH+ +E+W+
Sbjct  698  QM-KFNTAIAQLMVFVN----------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  772  ELGEKGYLFN-EKWPEYDEKMLSSDETTIAVQVNGKVRGSFEIAKDSEQALVEKTALKLP  830
             L   G  ++   WP YDE  L  ++  I VQ++GKV++ + +AKD  +  ++  AL   
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  831  NVAKHLEG  838
            +V  ++ G
Sbjct  807  KVQAEIAG  814

1076) Nther_0537 in NC_010718


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  547 bits (2066),  Expect = 9e-157, Method: Compositional matrix adjust.
 Identities = 375/862 (44%), Positives = 544/862 (64%), Gaps = 71/862 (8%)

Query  4    YQPQKIESKWQKRWQDEISYETEVDHNKDKYYVLEMFPYPSGK-LHMGHMRVYSIGDVLA  62
            Y+   IE+KWQ  W D+ ++ T  D +K K+Y L+MFPYPSG  LH+GH   Y+  D+L+
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RFQRMRGYNVLHPMGWDAFGLPAENAAIENQDLPSRWTYANIDNMKDQLQALGTSYDWKR  122
            RF+R +G NVLHPMGWDAFGLPAE+ A++  + P+  T  NI N K Q++ALG SYDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVSTCSPDYYKWTQWMFLQLYKNGLAYKKKAPVNWCPECETVLANEQV-ENGACWRCDSM  181
            EV+T  P+YYKWTQW+F +LY +GLAY    PVNW  E  T +ANE+V  +G+  R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VEQKQLSQWFFKITEYADRLDQDlelleeWPDRVKTMQKNWIGKSQGTEIDFPVKGSREK  241
            V +K + QW +KIT YA+RL +D     +WP+ +K MQ+NWIGKS G+++ F VK++   
Sbjct  184  VVRKPMRQWMLKITAYAERLLED-LEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  242  IRAFTTRPDTIFGATYMVLAPEHPMTEQLVQGTDQEKEVMDFIKGVHEMGKEAREAEDLE  301
            +  FTTRPDT+FGATY VLAPEH++ +  +  +DQ   V D+ +     +  AR     E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDA-ITTSDQAEAVADYKRQASLKSDLARTDLAKE  301

Query  302  KEGVFTGRWAINPLNGEEIPILVGNYVLMEYGTGAIMAVPAHDQRDFQFAHKYNLPIKEV  361
            K GV TG  AINP+NG E+P+ +++YVL  YGTGAIMAVPAHD+RD +FA ++NL I  V
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  362  VTPPEGEGKTESETHDELKKAYTDHGILINSPGYNGMTSEQAIEQITRDIENKGIGAGVT  421
            +   + E             A+T++G+ INS   +G+    AI ++   +E  G+G    
Sbjct  362  LEGGNVEE-----------AAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENV  410

Query  422  TYRLRDWLVSRQRYWGAPIPVLYCDQCGILPVPEDELPVQLP--EDVDFSQGSRNVLAAR  479
            TYRLRDWL SRQRYWG PIP++  ++    +VPE ELP+ LP   D+  S  + + LA  
Sbjct  411  TYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANV  470

Query  480  QDFVETSCPQCGGSAQRETDTMDTFVCSSWYFLRYTTPWDNEVPFRQEDVNYWMPVDQYI  539
             D +E +  + G  ++RET+TM     SSWY+LRY  P + E    +E ++ W+PVD Y+
Sbjct  471  TDWLEVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYV  529

Query  540  GGIEHAVLHLLYARFFTKVMYDQGYTNFKEPFSRLLAQGMV-------------------  580
            GG EHAVLHLLYARF  KV+YD G    KEPF +L+ QGM+                   
Sbjct  530  GGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVE  589

Query  581  NKDG---------------AKMSKSKGNVVSPDEILRTYGADTGRLFILFAAPPEKDLDW  625
            ++DG               AKMSKS  NVV+PD+++  YGADT R++ +F +P +  + W
Sbjct  590  KRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAW  649

Query  626  NDEGVEGCYRFLQRLYRlvndnqnlvdlqlddTKFTKEDKEYHRLIHKTIKKVTDDISER  685
            ++EG+EG  +FL+R+YRL+  ++              +    +++ + T+K VT+++ ++
Sbjct  650  SEEGLEGSRKFLDRVYRLITTKEIT----------EENSGALDKVYNETVKAVTEQV-DQ  698

Query  686  HNFNTAISAIMELTNASSKYKEQKEVNESLLRTGLETIVMLLAPFTPHIAEELWETL-GY  744
             +FNTAI+ +M + NA++K       ++ L+      +V L+APF+PH++EELW++L + 
Sbjct  699  MKFNTAIAQLMVFVNAANK-------EDKLFSDYAKGFVQLIAPFAPHLGEELWQALTAS  751

Query  745  QDSVHKLNWPSYDEKamvaeeaemvvQVNGKVRDHLTVPADSSEETIKEKALEREKVQKY  804
             +S+  + WPSYDE  +V ++ E+VVQ++GKV+  L V+ D S E ++E AL  EKVQ  
Sbjct  752  GESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAE  811

Query  805  ISGAEIKKVIVIPQKLVNIVCK  826
            I+G +I KVI +P+KLVNIV K
Sbjct  812  IAGKDIIKVIAVPNKLVNIVIK  833

1077) TOL_0681 in NC_020888


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  546 bits (2061),  Expect = 2e-156, Method: Compositional matrix adjust.
 Identities = 380/866 (44%), Positives = 564/866 (66%), Gaps = 49/866 (5%)

Query  6    YQPHTIEPAVQQQWEANQVFKAVVDTNKEKFYCLSMFPYPSGR-LHMGHVRNYTIGDVVS  64
            Y+  +IEP  Q  W  N+ FK+  D++K KFY L MFPYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  65   RFQRMQGKNVMQPMGWDAFGLPAENAAIKHKVAPAKWTKENIAYMKGQLKSLGFGYDWDR  124
            RF+R QG NV++PMGWDAFGLPAE+ A+     PA  T ENIA  K Q+++LGF+YDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  125  EIATCDPEYYRWEQWFFTTLIDKGLAYKKVSAVNWCPNDQTVLANEQVI-DGCCWRCDSV  183
            E+ T DP+YY+W QW+FT L +KGLAY    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  184  VERKEIPQWFIRITAYAEELLNDLDQLEGWPDQVKAMQRNWIGKSRGVQMRFGLKDRSDE  243
            V RK + QW ++ITAYAE LL+DL++++ WP+ +K MQRNWIGKS G ++ F +KD   +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  244  LEIYTTRPDTLMGVSYLavaaghalakeaaaTNSELAAFLDECKKSGTAEADLATV----  299
            + ++TTRPDTL G +Y     +   A   A T S+ A  + + K+ ++  +DLA      
Sbjct  243  FTVFTTRPDTLFGATY--AVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  300  EKKGMATGFTAIHPISGAEVPVWVANFVLMEYGTGAVMAVPAHDQRDWEFANKYDLAINQ  359
            EK G+ TG  AI+P++G E+PVW+A++VL  YGTGA+MAVPAHD+RDWEFA++++L I  
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  360  VIEGINGEEIDLAAAAFTEKGVLINSGEFDGLAFEQAFDAIAAKLVELGKGEVKTNYRLR  419
            V+EG N EE     AAFTE G+ INS+ +DGL    A+  +   L   G G+ +  YRLR
Sbjct  361  VLEGGNVEE-----AAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  420  DWGVSRQRYWGSPIPVIRNAAGDTMPAPASLQPVILP--TDVVMDGI-NSPIKNNPE-FE  475
            DW  SRQRYWG PIP+I+   G + + P S  P++LP   D+   G  +SP+ N  + +E
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  476  NIELDGEPVFRETDTFDTFMESSWYYARYCSPRCDDAMLDPKEANYWLPVDQYIGGIEHA  535
                DG    RET+T      SSWYY RY  P+  + + D    + WLPVD Y+GG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  536  ILHLLYARFFHKLLRDAGLVESDEPFKSLLCQGMVLAEAFYTTNDNGAKEWVNAADVTIE  595
            +LHLLYARF HK+L D G+V + EPF+ L+ QGM+L+ ++   +  GA   + A+D    
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY--RDSRGA---LVATDKVEK  590

Query  596  RDEKGRLLTAHRTVDGVEVQYSGMIKMSKSKNNGVDPQEAIELYGADTVRLYTMFAAPPE  655
            RD  G ++   +   G E++  +  KMSKS +N V+P++ +E YGADT+R+Y MF +P +
Sbjct  591  RD--GSFF---HVETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLD  644

Query  656  QTLEWSDSGVQGSQKFLQRVWRL-SYELLQQANAGTLENLSKDEQDVRRKVHETIQKVSD  714
             ++ WS+ G++GS+KFL+RV RL +   + + N+G+L+++           +ET++ V++
Sbjct  645  ASIAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALDKV----------YNETVKAVTE  694

Query  715  DIGRRYNFNTGIAAIMELMNALQKVDLSSNGGRGVVSEGLNAIIRMLSPMAPHITQALWV  774
            ++++  +FNT+IA +M ++NA +K D        + S+  ++++++++P APH+ + LW 
Sbjct  695  QVDQM-KFNTAIAQLMVFVNAANKED-------KLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  775  AFGNDGLVID-ATWPVVDESALVRDSITLVVQVNGKLRAKLEAPVSAGKdelealamade  833
            A+   G  I    WP  DES LV + + +VVQ++GK++AKL  +   +++EL+ +A+A+E
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  834  aVQKQLEGKTVRKVIVVPGKLVNIVV  859
             VQ ++ GK + KVI VP KLVNIV+
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVI  832

1078) leuS in NC_010483


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  546 bits (2062),  Expect = 2e-156, Method: Compositional matrix adjust.
 Identities = 362/840 (44%), Positives = 531/840 (64%), Gaps = 68/840 (8%)

Query  23   FYTPQRSEKPKYYALVMFPYPSGT-LHVGHVKNYVIGDIVARYKRMRGYNVLHPFGYDAF  81
            F T   + KPK+YAL MFPYPSG+ LHVGH   Y   DI++R+KR +G NVLHP G DAF
Sbjct  23   FKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSRFKRAQGHNVLHPMGWDAF  82

Query  82   GLPAENAAIEKGIHPEEWTRKNINTIRGQVKKLGISYDWSREIATCDEEYYKWTQWIFLQ  141
            GLPAE+ A++ G +P E T  NI  ++ Q++ LG+SYDW RE+ T D +YYKWTQWIF +
Sbjct  83   GLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTK  142

Query  142  LYKNGLAYKKKAAVNWCPKCKTVLANEQV-KDGKCERCGTSVTIRHLEQWFFKITDYAER  200
            LY +GLAY    +VNW     T +ANE+V  DG  ER G +V  + + QW +KIT YAER
Sbjct  143  LYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAER  202

Query  201  LLNDLDKLTGWPEHVKTMQRNWIGKSTGAEIDFPVEGSDTKIRVFTTRPDTLWGVTFMal  260
            LL+DL+ + +WPE +K MQRNWIGKSTGA++ F V ++D  + VFTTRPDTL G T+  L
Sbjct  203  LLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVL  261

Query  261  apesplveelvpeekkeelqefleRVKQQDRFRRTSVEAEKEGFFLGRYAINPVTGERIP  320
            APE +LV+ +   ++ E + ++  +   +  + RT +  EK G   G YAINPV G  +P
Sbjct  262  APEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAINPVNGKEMP  321

Query  321  IYVANYILMEYGTGAIMGVPAHDQRDFSFAKKYGIPIKVVIKPADRDLDPEKMEEAYEGE  380
            + +A+Y+L  YGTGAIM+VPAHD+RD  FAK++ + I  V+  ++ +      E A+  +
Sbjct  322  VWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVE------EAAFTED  375

Query  381  GIMVNSGPFDGTPSGEGIEKVINWLEEKGIGKRSVQYKLRDWLISRQRYWGAPIPIIYCE  440
            G+ +NS+ +DG   + +I K+++WLE  G+G+ +V Y+LRDWL+SRQRYWG PIPII  E
Sbjct  376  GLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWE  435

Query  441  KCGIVPVPEEDLPVRLPKDVEFLPTGQSPLSFHEGFKRTKCPICGG-EAQRETDTMDTFV  499
                 +VPE +LP+ LP   ++ P+G +  ++ +   +      +G  ++RET+TM    
Sbjct  436  DGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVKGRRETNTMPQWA  495

Query  500  DSSWYFLRYVNPHLEDKPFEPDDVNYWLPVDQYIGGVEHAVLHLLYSRFVTKVLHDLGYL  559
            +SSWY+LRY++PH  +K  + + ++ WLPVD Y+GG EHAVLHLLY+RF  KVL DLG +
Sbjct  496  GSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVV  555

Query  560  NFDEPFTNLFTQGMI----YKDG------------------------------AKMSKSK  585
               EPF +LF QGMI    Y+D+                              AKMSKS 
Sbjct  556  PTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSL  615

Query  586  GNVVSPDEMIEKYGADTLRMYILFMAPPEKDAEWSDAGIEGVHRFIKRLWNTFYTVLPFV  645
             NVV+PD+++E+YGADTLR+Y +FM+P +    WS+ G+EG ++F+ R+    Y ++   
Sbjct  616  KNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRV----YRLIT-T  670

Query  646  KEENTENLVLKNSTEKELRRKLHSIIKKITEDIEGGFKFNTAISGLMELVNHLSQYLNSV  705
            KE       + +     L +  +  +K +TE+++   KFNTAI+ LM        ++N+ 
Sbjct  671  KE-------ITEENSGALDKVYNETVKAVTEQVD-QMKFNTAIAQLM-------VFVNAA  715

Query  706  PQEEWNRKLLREIVEKLTLALSPFAPHLAEEFWHDLGNDSLVVQ-QAWPSYDPKALEVEE  764
             +E+   KL+ +    +   ++PFAPHL+EE+W+ L   +  +   +WPSYD   L  ++
Sbjct  716  NKED---KLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVEND  772

Query  765  VEIAIQINGKVRDKVVVPVDISEEALKRIVLERERVKEYVDGKPIRKFIYVKGRIVNIVV  824
            VEI +QI+GKV+ K+VV+ D+S E L+ + L  E+V+  + GK I K I V  ++VNIV+
Sbjct  773  VEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

1079) TtJL18_0246 in NC_017587


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  546 bits (2061),  Expect = 2e-156, Method: Compositional matrix adjust.
 Identities = 386/881 (44%), Positives = 560/881 (64%), Gaps = 58/881 (6%)

Query  4    YNPHAIEAKWQRFWEEK-GFMKAKDLPGGRGKQYVLVMFPYPSG-DLHMGHLKNYTMGDV  61
            Y+  AIE+KWQ FW ++  F  + D  +++ K Y L MFPYPSG +LH+GH   YT  D+
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTD--ASKPKFYALDMFPYPSGAGLHVGHPEGYTATDI  61

Query  62   LARFRRMQGYEVLHPMGWDAFGLPAENAALKFGVHPKDWTYANIRQAKESLRLMGILYDW  121
            L+RF+R QG +VLHPMGWDAFGLPAE+ A+  G +P + T  NI + K  +  +G+ YDW
Sbjct  62   LSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDW  121

Query  122  DREVTTCEPEYYRWNQWIFLKMWEKGLAYRAKGLVNWCPKCQTVLANEQVVEGRCWRHED  181
            DREV T +P+YY+W QWIF K+ EKGLAY A   VNW     T +ANE+V+ +    + +
Sbjct  122  DREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGG  181

Query  182  TPVEKRELEQWYLRITAYAERLLKDLEGLNWPEKVKAMQRAWIGRSEGAEILFPVEGKEV  241
             PV ++ + QW L+ITAYAERLL DLE ++WPE +K MQR WIG+S GA++ F V + + 
Sbjct  182  YPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDK  241

Query  242  RIPVFTTRPDTLFGATFLVLAPEHPLTLELAAPEKREEVLAYVEAAKRKTEIERQAEGRE  301
             + VFTTRPDTLFGAT+ VLAPEH+L   ++++++ E V  Y   A  K+++ R   ++E
Sbjct  242  DFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKE  301

Query  302  KTGVFLGAYALNPATGERIPIWTADYVLFGYGTGAIMAVPAHDQRDFEFAKKFGLPIKKV  361
            KTGV  G+YA+NP  G  +P+W ADYVL +YGTGAIMAVPAHD+RD EFAK+F L I  V
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  362  IerpgeplpeplerAYEEPGIMVNSGPFDGTPSEEGKRKVIAWLEEKGLGKGRVTYRLRD  421
            +        +  E A+ E G+ +NS+ +DG     +  K++ WLE  G+G+  VTYRLRD
Sbjct  362  L-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  422  WLISRQRYWGTPIPMVHCEACGvvpvpeeelpvllpDLKDIEDIRPKGK--SPLEAHPEF  479
            WL+SRQRYWG PIP++H E     +VPE ELP++   L    DIRP G   SPL    + 
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLV---LPVTKDIRPSGTGESPLANVTDW  473

Query  480  YETTCPKCGGPAKRdtdtmdtffdSSWYYLRYTDPKN-DRLPFDPEKANAWMPVDQYIGG  538
             E T    G  ++R+T+TM    +SSWYYLRY DP N ++L+ D E  + W+PVD Y+GG
Sbjct  474  LEVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLA-DEELLKQWLPVDIYVGG  531

Query  539  VEHAVLHLLYSRFFTKFLHDLGMVKVEEPFKGLFTQGMVMAWTDFGPVEVEGSAVRLPEP  598
             EHAVLHLLY+RF  K L DLG+V   EPF+ LF QGM++           G++ R    
Sbjct  532  AEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMIL-----------GTSYR----  576

Query  599  TRIRLEIPESELSLEDVRKMGAELRPHEDGTLHLWKPAVMSKSKGNGVMVGPFVKEQGAD  658
                 +   + ++ + V K ++ +   E G      PA MSKS  N V  +  V + GAD
Sbjct  577  -----DSRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGAD  631

Query  659  IARITILFAAPPENEMVWTEEGVQGAWRFLNRIYRRVAEDREALLATSGVFQAEALEGKD  718
              R+  +F +P +  + W+EEG++G+++FL+R+YR        L++T  +  +E   G  
Sbjct  632  TLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYR--------LITTKEI--TEENSGAL  681

Query  719  RELYGKLHETLKKVTEDLEALRFNTAIAALMEFLNALYEYRKDRPVTPVYRTAIRYYLQM  778
              +Y   +ET+K VTE+++ ++FNTAIA LM F+NA     K+  + + Y  +   ++Q+
Sbjct  682  DKVY---NETVKAVTEQVDQMKFNTAIAQLMVFVNAA---NKEDKLFSDYAKG---FVQL  732

Query  779  LFPFAPHLAEELWHWF--WPDSLFEAGWPELDEKALEKDVVEVAVQVNGRVRGTIRIPKD  836
            + PFAPHL+EELW+ +    +S+    WP  DE  L  + VE+ VQ++G+V++ + ++KD
Sbjct  733  IAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKD  792

Query  837  APLEVARAEALKVRNVQAHLEGKEVVKEIYVPGKILNLVVR  877
             + E  +  AL   +VQA++ GK+++K I VP K++N+V++
Sbjct  793  LSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

1080) leuS in NC_018690


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  546 bits (2062),  Expect = 2e-156, Method: Compositional matrix adjust.
 Identities = 363/866 (42%), Positives = 567/866 (66%), Gaps = 46/866 (5%)

Query  5    YNPSAIEPKVQQFWAENKVFKAVKDVTKEKYYCLSMLPYPSGK-LHMGHVRNYTIGDVVS  63
            Y+ +AIEPK Q FWA+N  FK+  D +K K+Y L M+PYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMIGKNVLQPMGWDAFGLPAEGAAVKNNTAPAKWTYENIEYMKGQLKMLGFSYDWDR  123
            R++R  G NVL+PMGWDAFGLPAE  A+     PA  T ENI   K Q++ LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVTTCRPEYYKWEQWFFTELYKKGLVYKKTSTVNWCPNDETVLANEQV-HEGCCWRCDTP  182
            EV T  P+YYKW QW+FT LY KGL Y     VNW  +  T +ANE+V  +G   R + P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VEQREIPQWFIKITDYAEELLNHLDNLPQWPDQVKTMQRNWIGRSEGVEITFKIAGSNAE  242
            V ++ + QW +KIT YAE LL++L+++ +WP+ +K MQRNWIG+S G ++TFK+ +++ +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LPVYTTRPDTFFGVSY--VavaaahplaemaaENNPALAEFIREAK-NTKVAEAELATME  299
            + V+TTRPDT+FG +Y  +A   A   A  ++++  A+A++ R+A  ++ +A ++LA  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGMATGLFAIHPLTGKEVPVWVANFVLMHYGTGAVMAVPAHDERDFEFAQKYGLQINQV  359
            K G+ TG +AI+P+ GKE+PVW+A++VL  YGTGA+MAVPAHDERD EFA+++ L+I   
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDI---  358

Query  360  IQPLDGAEWDFTKAAYTEHGKLINSAEFDGLDFNKAFNAIADKLESMKVGKRQVNFRLRD  419
            I  L+G+  +   AA+TE+G  INS  +DGLD   A+  + + LE+  VG+ +V +RLRD
Sbjct  359  IPVLEGG--NVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMMTTEDGEVVTVPMQDLPVILP--EDVVMNGV-QSPIKADPEWAKT  476
            W  SRQRYWG PIP++  EDG   +VP  +LP++LP   D+  +G  +SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  TY-NGKPALKETDTFDTFMESSWYYARYTCPQYHEGMLDSDEANYWLPVDQYIGGIEHAT  535
            T  +G  + +ET+T      SSWYY RY  P+  E + D +  + WLPVD Y+GG EHA 
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLLYFRFFHKLLRDAGILNSDEPATKLLCQGMVLADAFYYTSPTNERIWVSPTQVTLER  595
            +HLLY RF HK+L D G++ + EP  KL+ QGM+L+ ++      + R     + V+ ++
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSR----GALVATDK  587

Query  596  DEKGRIIKATDPEGRELVHSGMTKMSKSKNNGIDPQEMVEKYGADTVRLFMMFASPAEMT  655
             EK R     + E  E ++ + +KMSKS +N ++P+++VE+YGADT+R++ MF +P + +
Sbjct  588  VEK-RDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  656  LEWQESGVEGAKRFLGRVWNLVYEYSQNPATAALDVAALSKAQKELRRDVHKTIAKVSDD  715
            + W E G+EG+++FL+R    VY        +  + +AL K  +E       T+  V+++
Sbjct  647  IAWSEEGLEGSRKFLDR----VYRLITTKEITEENSGALDKVYNE-------TVKAVTEQ  695

Query  716  IGRRQTFNTAIAAIMELMNKLTKASLDNDQDKAVMAEALSAVVRMLYPITPHICFELWQA  775
            +++ + FNTAIA +M ++N         +++  + ++   + V+++ P++PH+  ELWQA
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  776  L-GNNDTIDFAPWVVADESAMVEDEKLVVVQVNGKVRGKVTVSATATEDEVKAIAKADAN  834
            L ++ ++I + PW   DES +VE++  +VVQ++GKV++K+ V+   + +E++ +A A+ +
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  835  VAKFLEGVEIVKEIYVPYKMLSFAVK  860
            V   + G +I+K I VP K++++ +K
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVIK  833

1081) leuS in NC_021738


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  546 bits (2062),  Expect = 2e-156, Method: Compositional matrix adjust.
 Identities = 361/876 (42%), Positives = 568/876 (65%), Gaps = 66/876 (7%)

Query  5    YNPSEIEPKVQRYWAENKVFKAVKDVTKEKYYCLSMLPYPSGK-LHMGHVRNYTIGDVVS  63
            Y+ + IEPK Q +WA+N  FK+  D +K K+Y L M+PYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMIGKNVLQPMGWDAFGLPAEGAAVKNNTAPAKWTYENIEYMKGQLKMLGFSYDWDR  123
            R++R  G NVL+PMGWDAFGLPAE  A+     PA  T ENI   K Q++ LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVTTCRPEYYKWEQWFFTELYKKGLVYKKTSTVNWCPNDETVLANEQV-HEGCCWRCDTP  182
            EV T  P+YYKW QW+FT LY KGL Y     VNW  +  T +ANE+V  +G   R + P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VEQREIPQWFIKITDYAEELLNQLDNLPQWPDQVKTMQRNWIGRSEGVEITFKIAGSNVE  242
            V ++ + QW +KIT YAE LL++L+++ +WP+ +K MQRNWIG+S G ++TFK+ +++ +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LPVYTTRPDTFFGVSY--VaiaaahplaelaaQNNPALAEFIREAK-NTKVAEAELATME  299
            + V+TTRPDT+FG +Y  +A   A   A  ++++  A+A++ R+A  ++ +A ++LA  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGMATGLFAIHPLTGKEVPVWVANFVLMHYGTGAVMAVPAHDERDFEFAQKYDLQINQV  359
            K G+ TG +AI+P+ GKE+PVW+A++VL  YGTGA+MAVPAHDERD EFA++++L+I   
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDI---  358

Query  360  IQPLDGSEWDFSKAAYTEHGKLINSAEFDGLEFDVAFTAIADKLEAMGVGKRQVNFRLRD  419
            I  L+G+  +   AA+TE+G  INS  +DGL+   A++ + + LEA GVG+ +V +RLRD
Sbjct  359  IPVLEGG--NVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMMTTEEGEVVTVPLQDLPVILP--EDVVMNGV-QSPIKADPEWAKT  476
            W  SRQRYWG PIP++  E+G   +VP  +LP++LP   D+  +G  +SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  TY-NGKPALRETDTFDTFMESSWYYARYTCPQYHEGMLDSDEANYWLPVDQYIGGIEHAT  535
            T  +G  + RET+T      SSWYY RY  P+  E + D +  + WLPVD Y+GG EHA 
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLLYFRFFHKLLRDAGILNSDEPATKLLCQGMVLADAFYYTSPTNERIWVSPTQVTLER  595
            +HLLY RF HK+L D G++ + EP  KL+ QGM+L+ ++                    R
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY--------------------R  576

Query  596  DEKGRIIKATDPQRR----------ELVHSGMTKMSKSKNNGIDPQEMVEKYGADTVRLF  645
            D +G ++ +   ++R          E ++ + +KMSKS +N ++P+++VE+YGADT+R++
Sbjct  577  DSRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVY  636

Query  646  MMFASPAEMTLEWQESGVEGAKRFLGRVWNLVYSYAQNPATTALDVNALDKDQKELRRDV  705
             MF +P + ++ W E G+EG+++FL+R    VY        T  +  ALDK  +E     
Sbjct  637  EMFMGPLDASIAWSEEGLEGSRKFLDR----VYRLITTKEITEENSGALDKVYNE-----  687

Query  706  HKTIAKVSDDIGRRQTFNTAIAAVMELMNKLTKAPLETEQDKAVMAEALSAVVRMLYPIT  765
              T+  V++++++ + FNTAIA +M ++N        ++++  + ++   + V+++ P++
Sbjct  688  --TVKAVTEQVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFA  737

Query  766  PHICFELWQVL-GNEQTIDFAPWVQADESAMVEDEKLVVVQVNGKVRGKITVSATATEDE  824
            PH+  ELWQ L ++ ++I + PW   DES +VE++  +VVQ++GKV++K+ V+   + +E
Sbjct  738  PHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREE  797

Query  825  VKAIAKADPNVAKFLDGQQIVKEIYVPFKMLSFAVK  860
            ++ +A A+ +V   + G++I+K I VP K++++ +K
Sbjct  798  LQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

1082) Thewi_0350 in NC_015958


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  546 bits (2059),  Expect = 3e-156, Method: Compositional matrix adjust.
 Identities = 379/849 (45%), Positives = 544/849 (65%), Gaps = 59/849 (6%)

Query  5    VDVDRKWQKRWEETKLYKFNPENVDKKLYCLEMFSYPSGAKLHVGHWYNYGPTDSWARMK  64
              ++ KWQ  W +   +K   +    K+Y L+MF+YPSGA LHVGH   Y +TD  +R K
Sbjct  7    TAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSRFK  66

Query  65   RMQGYEVFHPMGFDAFGLPAENYAIKTGIHPYDSTMENIRTMEKQLREMGATFDWDYEVI  124
            R QG +V+HPMG DAFGLPAE+YA+ TG +P + T ENI    +Q+  +G ++DWD EV 
Sbjct  67   RAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDREVN  126

Query  125  TCLPEYYKWTQWIFLKLFEAGLAYRKKAPVNWCPSCQTVLANEQVI-DGKCERCGTEVTK  183
            T  P+YYKWTQWIF KL+E GLAY    PVNW     T +ANE+V+ DG  ER G  V +
Sbjct  127  TTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVR  186

Query  184  KDLTQWFFKITAYAeellekldeldWPEKTKIMQRNWIGKSDGAEIEFKVDGKDLTFKVF  243
            K + QW +KITAYAE LLE L+E+DWPE  K MQRNWIGKS GA++ FKV + D  F VF
Sbjct  187  KPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVF  246

Query  244  TTRADTLYGATYVVIAPEHEIVDLITTDEYRQSVEEYKEYARKQSEIERLSTEKEKTGVF  303
            TTR+DTL+GATY V+APEH +VD ITT +  ++V +YK  A  +S++ R    KEKTGV 
Sbjct  247  TTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVW  306

Query  304  TGAYAIHPLTGEKLPIWIADYVLATYGTGCVMAVPAHDERDYEFATKYDLPIKRVIKGIG  363
            TG+YAI+P+ G  +P+WIADYVLA+YGTG +MAVPAHDERD EFA +++L I  V+ G G
Sbjct  307  TGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEG-G  365

Query  364  DIDDSLPFVEYGVLIDSGEFTGMKSEEARIKIVEKLKQEGRAEFKVNYRLRDWLVSRQRY  423
            +++++ +F E G+ I+S+ + G+    A  K+VE L  EG ++ +V YRLRDWL SRQRY
Sbjct  366  NVEEA-AFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRY  424

Query  424  WGAPIPVIH--CERCGIvpvpeedlpvllpYDVEFAPTGESPLKKHEGFMNVTCPKCGGK  481
            WG PIP+IH        VP +E  L + +  D+  + TGESPL +  + ++VT    G K
Sbjct  425  WGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED-GVK  483

Query  482  ALRDPDTLDTFVDSSWYFLRYPDNKNDKEPFNKEWINKMLPVDKYVGGAEHATMHLLYAR  541
            + R+ +T+    +SSWY+LRY D  N     + E +++ LPVD YVGGAEHA +HLLYAR
Sbjct  484  GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYAR  543

Query  542  FVTKALRDLGYLDFDEPFKSLVHQGTILGP------------------------------  571
            F  K L DLG +   EPF+ L +QG ILG                               
Sbjct  544  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEE  603

Query  572  ---DGSRMSKSKGNVISPDEYIKEYGSDVFRLYLMFGFAYSEGGPWNDDGIKAISRFINR  628
                 ++MSKS  NV++PD+ + +YG+D +R+Y MF  +   + +W+++G+ +  +F++R
Sbjct  604  LEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR  663

Query  629  VERFIDKFIETRNNPGKTKDEMGKDENELNYVRHYAIKGVTEDAERFQFNTAIARIMELV  688
            V R+I            TK+    +   L+ V + ++K+VTE+ ++ +FNTAIA++M +V
Sbjct  664  VYRLI-----------TTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFV  712

Query  689  NALYKYETDVEVKNIKFYEEVVTDLIRLLAPFAPHFSEEMWEKLGYEYSVFN-QKWPKWD  747
            NA          K+ K++ +   ++++L+APFAPH++EE+W+ L      ++   WP  D
Sbjct  713  NA--------ANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYD  764

Query  748  EKALQRDVVEIAVQVNGKVRGRLEVPSNATDEEVEKLALSDKNVKAYVDGKEIKKVIVVK  807
            E  L  + VEI VQ++GKV+++L V+ + + EE++ +AL++ +V+A + GK+I KVI V 
Sbjct  765  ESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVP  824

Query  808  NRLVNIVAK  816
            N+LVNIV K
Sbjct  825  NKLVNIVIK  833

1083) Tbis_2429 in NC_014165


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  546 bits (2059),  Expect = 3e-156, Method: Compositional matrix adjust.
 Identities = 363/852 (43%), Positives = 532/852 (63%), Gaps = 62/852 (7%)

Query  6    YDPQALQAKWLPRWEELNTFAAVEDPADPRPRRYMLDMFPYPSG-DLHMGHGEAFAIGDV  64
            YD  A+++KW + W + +TF +  D++  +P+ Y LDMFPYPSG +LH+GH E+++  D+
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDAS--KPKFYALDMFPYPSGAGLHVGHPEGYTATDI  61

Query  65   VARYWFQKGYNVLHPIGWDSFGLPAENAAIKRNAHPAEWTYANIDTQARSFKQYATSFDW  124
            ++R+   +G NVLHP+GWD+FGLPAE+ A+    +PAE T  NI    R ++  + S+DW
Sbjct  62   LSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDW  121

Query  125  SRRLHTSDPEYYRWNQWLFLRFYERGLAYRKDGLVNWCPKDQTVLANEQVI-NGRCERCQ  183
             R ++T+DP+YY+W QW+F ++YE+GLAY  +  VNW     T +ANE+V+ +G  ER  
Sbjct  122  DREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGG  181

Query  184  SEVVRRKLTQWYFKITEYADRLLDDMKQLEGKWPERVLTMQRNWIGRSTGADVQFKIEGR  243
              VVR+ + QW +KIT YA+RLL+D+ +++  WPE +  MQRNWIG+STGA+V FK+ + 
Sbjct  182  YPVVRKPMRQWMLKITAYAERLLEDLEEVD--WPESIKDMQRNWIGKSTGANVTFKVKDT  239

Query  244  EEPVTVFTTRPDTLYGATFFVVAPDSPLADEIVAPDRREALARYKAEVAKLSDIERLSTE  303
            +   TVFTTRPDTL+GAT+ V+AP+ +L D I ++D+ EA+A YK + +  SD+ R    
Sbjct  240  DKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA  299

Query  304  KEKTGVFLGVYAINPVNGERLPVWAADYVLSDYGHGAIMAVPAHDQRDLDFALKFGLPVR  363
            KEKTGV  G YAINPVNG  +PVW ADYVL+ YG GAIMAVPAHD+RD +FA +F L + 
Sbjct  300  KEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDII  359

Query  364  VVVDTGEPDPAETGIATPGEGKLINSGPLNGLSKAEAIQKMIEILTENGTGKAAVNYRLR  423
             V++ G+ + A    A   +G  INS+ L+GL KA AI KM+E L  +G G+  V YRLR
Sbjct  360  PVLEGGNVEEA----AFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  424  DWLVSRQRYWGTPIPIIHCPSCGEVPVPDDQLPVTLPDLRGEALAPKGVSPLASAEEWVN  483
            DWL SRQRYWG PIPIIH       +VP+ +LP+ LP  ++   +  G SPLA+  +W++
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  484  VDCPKCGGPAKRDTDTMDTFVDSSWYFLRYCDPDYEDGPFNVEKVRTWCPVDQYVGGVEH  543
            V     G  ++R+T+TM    +SSWY+LRY DP+  +   + E ++ W PVD YVGG EH
Sbjct  476  V-TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEH  534

Query  544  AVLHLLYSRFFTKVLYDMGLVDFTEPFQRLLNQGQVINQG--------------------  583
            AVLHLLY+RF  KVLYD+G+V   EPFQ+L+NQG ++  +                    
Sbjct  535  AVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGS  594

Query  584  --------------KAMSKSLGNGVDLGEQIEKYGVDAVRLTMVFAGPPEDDIDWADVSP  629
                            MSKSL N V+ ++ +E+YG D++R+  +F GP +  I W++ + 
Sbjct  595  FFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGL  654

Query  630  AASQKFLARALRVMTEAGAASAPGVDFSKGDVALRKVTHRVIDEVTKLVEAYRFNVAVAR  689
             +S+KFL R  R++T    +   +        AL KV +  +  VT  V+  +FN A+A+
Sbjct  655  EGSRKFLDRVYRLITTKEITEENS-------GALDKVYNETVKAVTEQVDQMKFNTAIAQ  707

Query  690  MMELTTAIRRAIDSGPGAADPAVREAAETLAIMLSLVAPYTAEEGWERLGHKP-SVAKAG  748
            +M +  A  +         D    + A  +  +++  AP  +EE W+ L     S++   
Sbjct  708  LMVFVNAANK--------EDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVP  759

Query  749  WPEADPQLLVQESVTCVVQVGGKLRDRLTVPPDISeaelerlalaSEKVQRYLSG-APRK  807
            WP  D   LV++ V  VVQ+ GK++ +L V+ D+S  EL+ +ALA+EKVQ  ++G    K
Sbjct  760  WPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIK  819

Query  808  VIIRAPKLINIV  819
            VI  + KL+NIV
Sbjct  820  VIAVPNKLVNIV  831

1084) VEA_004217 in NC_013456


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  546 bits (2059),  Expect = 3e-156, Method: Compositional matrix adjust.
 Identities = 371/868 (43%), Positives = 563/868 (65%), Gaps = 53/868 (6%)

Query  5    YNPQDIEQKVQKHWDDNKTFVVSEDPNKEKFYCLSMFPYPSGR-LHMGHVRNYTIGDVVS  63
            Y+   IE K Q  W DN TF  + D++K KFY L MFPYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RFQRLQGKNVMQPIGWDAFGLPAENAAVKNKTAPAPWTYENIEYMKNQLKLLGFGYDWNR  123
            RF+R QG NV++P+GWDAFGLPAE+ A+     PA  T ENI   K Q++ LGF+YDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EFATCTPEYYRWEQEFFTKLYEKGLVYKKTSSVNWCPNDQTVLANEQV-EDGCCWRCDTP  182
            E  T  P+YY+W Q +FTKLYEKGL Y    +VNW  +  T +ANE+V  DG   R + P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VEQKEIPQWFIKITEYAQELLDDLDKLEGWPEMVKTMQRNWIGRSEGVELKFEVKG-QQD  241
            V +K + QW +KIT YA+ LL+DL+ ++ WPE +K MQRNWIG+S G ++ F VK+ ++D
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  242  LEVYTTRPDTLMGVTYVGIaaghplaalaaennpelaaFIDECKNNKVAEAELA----TM  297
            + V+TTRPDTL G TY  +A+ H+L    + ++   A  + + K +    ++LA    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEA--VADYKRQASLKSDLARTDLAK  300

Query  298  EKKGMATGLTAIHPLNGREVPVYVANFVLMDYGTGAVMAVPAHDQRDYEFATKYGLDIVP  357
            EK G+ TG  AI+P+NG+E+PV +A++VL  YGTGA+MAVPAHD+RD EFA ++ LDI+P
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  358  VIKPADGSELDISEAAYTEKGVLFDSGEFDGLEFQAAFDAIAAKLEAEGKGTKTVNFRLR  417
            V+  +     ++ EAA+TE G+ ++S+ +DGL+  +A+  +   LEAEG G   V +RLR
Sbjct  361  VLEGG-----NVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  418  DWGVSRQRYWGAPIPMVTTEDGEVHPVPADQLPVILP--EDVVMDGVT-SPIKADKEWAK  474
            DW  SRQRYWG PIP++  EDG   +VP  +LP++LP   D+   G   SP+    +W  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  475  TTF-NGEPALRETDTFDTFMESSWYYARYCSPQADDIL-DPEKANYWLPVDQYIGGIEHA  532
             T  +G  + RET+T      SSWYY RY  P+  + L D E  + WLPVD Y+GG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  533  CMHLLYSRFFHKLLRDAGYVTSDEPFKQLLCQGMVLADAFYFENEKGGKEWVAPTDVAVE  592
             +HLLY+RF HK+L D G V + EPF++L+ QGM+L+ +  + + +G+   + +TD    
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS--YRDSRGA---LVATDKVEK  590

Query  593  RDGK-GRITSAKDTEGRDVTHSGMIKMSKSKNNGIDPQEMVDKYGADTVRLFMMFASPAD  651
            RDG   ++ ++ + E       +  KMSKS +N ++P+++V++YGADT+R++ MF +P D
Sbjct  591  RDGSFFHVETGEELE------QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLD  644

Query  652  MTLEWQESGVEGANRFLKRVWKLVKEHTAKGAAEAVDTAALSGDQKALRRDVHKTIAKVT  711
             ++ W E G+EG+ +FL RV +L+   T+K  +E         +  AL +  + T+  VT
Sbjct  645  ASIAWSEEGLEGSRKFLDRVYRLI---TTKEITEE--------NSGALDKVYNETVKAVT  693

Query  712  DDIARRQTFNTAIAAIMELMNKLAKAPQESAQDRAILDEALKAIVVMLYPITPHISYELW  771
            +++ + + FNTAIA +M ++N        + ++  ++ +  K++V ++ P++PH++ ELW
Sbjct  694  EQVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELW  745

Query  772  AALGETD--IDNAAWPTFDEKALVEDEKTIVVQVNGKLRAKLTVPADISKDDIEQLGLND  829
             AL  ++  I   +WP++DE  LVE++  IVVQ++GK++AKL V+ D+S++++++++L +
Sbjct  746  QALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALAN  805

Query  830  ENVVKFTDGLTIRKVIYVPGKLLNIVAN  857
            E+V     G  I KVI VP KL+NIV +
Sbjct  806  EKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

1085) leuS in NC_018679


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  546 bits (2059),  Expect = 3e-156, Method: Compositional matrix adjust.
 Identities = 364/873 (42%), Positives = 560/873 (65%), Gaps = 54/873 (6%)

Query  6    YNPKDIEQRVQQYWEENQSFKANDDVEKEKFYCLSMFPYPSGR-LHMGHVRNYTIGDVIS  64
            Y+   IE + Q +W +N++FK+  D  K KFY L MFPYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  65   RFQRMQGKNVLQPMGWDAFGLPAENAAINNNTAPAKWTYSNIDYMKNQLRSLGFGYDWDR  124
            RF+R QG NVL+PMGWDAFGLPAE+ A++    PA  T  NI   K Q+ +LGF+YDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  125  EVTTCKSDYYRWEQWFFTRLYEKGLVYKKNSTVNWDPVDQTVLANEQVI-DGRGWRSGAL  183
            EV T  ++YY+W QW+FT+LYEKGL Y  +  VNW     T +ANE+V+ DG + R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  184  VEQKEIPQWFIKITDYAeellqdleqleeWPDQVRAMQANWIGRSEGVEITFDLASAVND  243
            V +K + QW +KIT YA E L +  +  +WP+ ++ MQ NWIG+S G ++TF +  + + 
Sbjct  184  VVRKPMRQWMLKITAYA-ERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDK-  241

Query  244  IADLTVYTTRPDTFYGVTYVAVAAQHPLAEFAAKSNPDLAAFIDECKNTKVAEAELA---  300
              D+TV+TTRPDT++G TY  +A++H+L +  A + +D A  + + K      ++LA   
Sbjct  242  --DFTVFTTRPDTLFGATYAVLAPEHALVD--AITTSDQAEAVADYKRQASLKSDLARTD  297

Query  301  -TMEKKGFATGFEVVHPLTGEKLPIWVANFVLMDYGSGAVMAVPGHDQRDWEFATKYNLP  359
             + EK G  TG   ++P+ G  +P+W+A++VL  YG+GA+MAVP+HD+RDWEFA ++NL 
Sbjct  298  LAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLD  357

Query  360  IQQVIAPNAGDEDKCDLTVSAFTEKGSLINSDKFDGLEFDAAFNGIADELESKGCGKRKV  419
            I  V+     +E       +AFTE G  INSD +DGL+  +A+  + + LE+ G G+ +V
Sbjct  358  IIPVLEGGNVEE-------AAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENV  410

Query  420  NYRLRDWGVSRQRYWGAPIPMLNLENGESVPVPADQLPVVLP--EDVEMNGVT-SPIKAD  476
             YRLRDW  SRQRYWG PIP+++ E+G S +VP  +LP+VLP   D+  +G   SP+   
Sbjct  411  TYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANV  470

Query  477  PEWAKTTY-NGEAALRETDTFDTFMESSWYYARYACATNNDAMLDPTSANYWLPVDQYIG  535
             +W   T  +G  + RET+T      SSWYY RY  + N + + D    + WLPVD Y+G
Sbjct  471  TDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVG  530

Query  536  GIEHAILHLLYSRFFHKLLRDEGLVNSDEPFKRLLCQGMVLADSYYREDASGKKTWFSPT  595
            G EHA+LHLLY+RF HK+L D G+V + EPF++L+ QGM+L+ S YR+  ++        
Sbjct  531  GAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS-YRDSRGAL-------  582

Query  596  EVSTEKDDKGRIVKAWLTADGEEVIHGGMTKMSKSKNNGIDPQEVIDQYGADTVRLFTMF  655
             V+T+K +K     + +  +  E ++ + +KMSKS +N ++P++V++QYGADT+R++ MF
Sbjct  583  -VATDKVEKRD--GSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMF  639

Query  656  AAPPEQTLEWVDSGVEGANRFLRRIWKLVTEHVEKGTSEAIDVKALSKDQQALRREVHKT  715
             +P + ++ W + G+EG+ +FL R+ +L+T    K  +E         +  AL +  + T
Sbjct  640  MGPLDASIAWSEEGLEGSRKFLDRVYRLIT---TKEITEE--------NSGALDKVYNET  688

Query  716  IEKVSDDLGRRQTFNTAVAAVMELLNHLQKAPQEDAQDIAIMREACESILLLLNPITPHI  775
            +  V++++++ + FNTA+A +M ++N  +K  +       +  +   +++ L+ P++PH+
Sbjct  689  VKAVTEQVDQMK-FNTAIAQLMVFVNAANKEDK-------LFSDYAKGFVQLIAPFAPHL  740

Query  776  AHELWKVL-GHSEDIDLAPWPQADKAALVEDEKLIIVQVNGKVRAKMTiaadaskesiee  834
            ++ELW+ L + +E I   PWP  D + LVE++  I+VQ++GKV+AK+ +A D S+E ++E
Sbjct  741  GEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQE  800

Query  835  sakeQPNVQQFIEGKTIRKVIVVPGKLVNIVAN  867
             A  + +VQ  I GK I KVI VP KLVNIV +
Sbjct  801  VALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

1086) HMPREF0946_01200 in NC_022196


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  546 bits (2060),  Expect = 3e-156, Method: Compositional matrix adjust.
 Identities = 346/848 (41%), Positives = 541/848 (64%), Gaps = 50/848 (5%)

Query  4    YEFKEIEKKWQERWSKDNIFKTENEVEGKENYYVLSMLPYPSGK-LHVGHARNYTIGDVI  62
            Y+   IE KWQ  W+ ++ FKT  +  +K ++Y L M+PYPSG  LHVGH+  YT  D++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDA-SKPKFYALDMFPYPSGAGLHVGHPEGYTATDIL  62

Query  63   SRYKRMKGYNVLQPMGWDSFGLPAENAAIQNGTHPAIWTKSNIENMRRQLKLMGFSYDWE  122
            SR+KR +G NVL+PMGWD+FGLPAE+ A++ G +PA  T  NI N +RQ++ +GFSYDW+
Sbjct  63   SRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWD  122

Query  123  REIASYTPEYYKWNQWLFKRMYEKGLIYKKKSLVNWCPDCQTVLANEQV-EDGMCWRHSK  181
            RE+ +  P+YYKW QW+F ++YEKGL Y     VNW  +  T +ANE+V  DG    ++ 
Sbjct  123  REVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTS-ERGG  181

Query  182  THVIQKELEQWFFKITDYADELLEGHEEIKDGWPEKVLTMQKNWIGKSFGTELKLKVVET  241
              V++K + QW +KIT YA+ LLE+ EE+  +WPE +  MQ+NWIGKS G+++ +KV +T
Sbjct  182  YPVVRKPMRQWMLKITAYAERLLEDLEEV--DWPESIKDMQRNWIGKSTGANVTFKVKDT  239

Query  242  GEDLPIFTTRIDTIYGVSYAVVAPEHPIVEKILKVNPSIKDKVTEMKNTDI----IERGA  297
            + D+ +FTTR DT++G +YAV+APEH++V+ I   + +  + V++ K        + R  
Sbjct  240  DKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQA--EAVADYKRQASLKSDLARTD  297

Query  298  EGREKNGIDSGWHIENPVNKEIVPLWIADYVLMNYGTGAVMGVPAHDERDFVFAGKYNLP  357
             ++EK G+ +G    NPVN   +P+WIADYVL +YGTGA+M+VPAHDERD  FA ++NL 
Sbjct  298  LAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLD  357

Query  358  VKQVITSKKTDEKVELPYLEEGVMINSGEFNGLNSKEALVKIAEYVEEKGYGQRTYKYRL  417
            +  V+ + + +E    ++ E+G+ INS+ ++GL+   A+ K+ E +E  G G+    YRL
Sbjct  358  IIPVLEGGNVEEA---AFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRL  414

Query  418  KDWGISRQRYWGTPIPVLYCEKCGEVLEKDENLPVLLPDDIEFSGNG---NPLETSNKFK  474
            +DW +SRQRYWG PIP++  E        + +LP++LP   ++  +G   +PL       
Sbjct  415  RDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWL  474

Query  475  EATCPCCGGKARRDTDTMDTFVDSSWYFLRYCDPKNINLPFSKEIVDKWTPVDQYIGGVE  534
            E T    G K+RR+T+TM    +SSWY+LRY DP N +     E++ +W PVD Y+GG E
Sbjct  475  EVTRE-DGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAE  533

Query  535  HAVMHLLYARFFYKVLRDLGLLSSNEPFKRLLTQGMVLGPSYYSEKENKYLFSKDVVIKG  594
            HAV+HLLYARF  KVL DLG+++++EPF++L+ QGM+LG SY   +    L + D V K 
Sbjct  534  HAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGA--LVATDKVEKR  591

Query  595  DKAY--SQSGEKLQVKVEKMSKSKNNGVDPEEMLDKYGADTTRLFIMFAAPPEKELEWNE  652
            D ++   ++GE L+    KMSKS +N V+P++++++YGADT R++ MF +P +  + W+E
Sbjct  592  DGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSE  651

Query  653  NGLAGAYRFLTRVWRLVFENSELIKKSNDKIDYNKLSKEDKTLLIKL-NQTIKKVTDAIE  711
            +GL G+ +FL RV RL              I  + ++ E+   L K+ N+T+K VT+ ++
Sbjct  652  EGLEGSRKFLDRVYRL--------------ITTKEITEENSGALDKVYNETVKAVTEQVD  697

Query  712  NNYHFNTAIAANMELINEVQTYVSSSMNSEQAAKILGYTLKKIIIMLSPFVPHFCDEIWE  771
            +   FNTAIA  M ++N           +++  K+++   K ++ +++PF PH+ +E+W+
Sbjct  698  QM-KFNTAIAQLMVFVN----------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  772  ELGEKGYLFN-EKWPEYDEKMLSSDETTIAVQVNGKVRGSFEIAKDSEQALVEKTALELP  830
             L   G  ++   WP YDE  L  ++  I VQ++GKV++ + +AKD  +  ++  AL   
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  831  NVAKHLEG  838
            +V  ++ G
Sbjct  807  KVQAEIAG  814

1087) Sterm_0736 in NC_013517


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  546 bits (2060),  Expect = 3e-156, Method: Compositional matrix adjust.
 Identities = 347/847 (41%), Positives = 538/847 (64%), Gaps = 50/847 (5%)

Query  4    YNPKEIENKWQSKWNKDNIFKSENVSDKENYYILEMFAYPSG-NLHVGHLRNYTIGDAIA  62
            Y+   IE KWQ+ W  ++ FK+   + K ++Y L+MF+YPSG  LHVGH   YT  D ++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKKMKGFNVLHPFGWDSFGLPAENAAIENKAHPGDWTRKNIDNMKRQLKLMGISHDWSR  122
            R+K+ +G NVLHP GWD+FGLPAE+ A++   +P++ T  NI N KRQ++ +G+S DW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  ELATYQENYYKWNQWMFIKMYEKGLVYKKKSYVNWCPECNTVLANEQV-EDGKCWRHSKT  181
            E+ T + NYYKW QW+F K+YEKGL Y     VNW  E  T +ANE+V  DG    ++  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTS-ERGGY  182

Query  182  DVIQKELDQWYFKITDYSEELLQSHDDLAGNWPDKVITMQKNWIGKSYGTEIDFVLEDGK  241
             V++K + QW +KIT Y+E LL+  +++  +WP+ +  MQ+NWIGKS G+++ F + D  
Sbjct  183  PVVRKPMRQWMLKITAYAERLLEDLEEV--DWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  242  TKIPAFTTRPDTLYGVTYVVLAPEHPVVEDIILKDNPALKV--KTDAMINEDKIERTAED  299
              +  FTTRPDTL+G TY VLAPEH++V+ I   D++      K +A ++ D + RT   
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSD-LARTDLA  299

Query  300  KEKEGFFTGKYVTNPVNGEKIPLWVGNYVLMDYGTGAVMAVPAHDERDFLFAGKYDLPLR  359
            KEK G  TG Y  NPVNG  +P+W+++YVL  YGTGA+MAVPAHDERD  FA +++L + 
Sbjct  300  KEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDII  359

Query  360  VVIEPEGEKLDISTMKQAYTGEGILVNSDKFDGMKNNDAKTAVSEYLEEIKGGLRTVNYR  419
             V+  EG +++      A+T +G+ +NSD +DG+ +  A + + E LE    G   V YR
Sbjct  360  PVL--EGGNVE----EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYR  413

Query  420  LHDWLLSRQRYWGTPIPALYCEKCGLVMEKIENLPVKLPMDIEFSGVG---NPLETSEQF  476
            L+DWL+SRQRYWG PIP +  E          +LP+ LP+  ++   G   +PL    + 
Sbjct  414  LRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDW  473

Query  477  KNVTCPVCGGTAKRETDTMDTFVDSSWYYLRFLNPNLDTAPFDKTDADNWTPVDQYIGGV  536
             +VT    G  ++RET+TM    +SSWYYLR+++P+      D     +W PVD Y+GG 
Sbjct  474  LEVTRE-DGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGA  532

Query  537  EHAVMHLLYARFFHKVLRDMGLLSSNEPFRRLLTQGMVLGPSYYSNEERKFYFEADVNVD  596
            EHAV+HLLYARF HKVL D+G+++++EPF++L+ QGM+LG SY   + R     +D +V+
Sbjct  533  EHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY--RDSRGALVATD-KVE  589

Query  597  NKTGKAYSKKTGEELAVKVEKMSKSKNNGVDPEVIVKEYGADSARVFSLFAAPPEKELEW  656
            ++ G  +   TGEEL     KMSKS +N V+P+ +V +YGAD+ RV+ +F +P +  + W
Sbjct  590  KRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAW  649

Query  657  NMNGLAGAYRFLNRLFLLIEDTKEFSEAGEIDHGKRNNEDSEIQKKLHQTVKKVSESMED  716
            + +GL G+ +FL+R++ LI  TKE++E          ++ + ++K  ++TVK V+E +++
Sbjct  650  SEEGLEGSRKFLDRVYRLI-TTKEITE----------ENSGALDKVYNETVKAVTEQVDQ  698

Query  717  NFHFNTAIAALMELLNDMTSYRQKVIDTGKISSESKKIWREVMEKTVLMLSPFAPHIADE  776
               FNTAIA LM ++N               ++   K+  +     V +++PFAPH+++E
Sbjct  699  -MKFNTAIAQLMVFVNA--------------ANKEDKLFSDYAKGFVQLIAPFAPHLGEE  743

Query  777  LWSA--SGREGYAFLESWPEYIEELTKESKINLVVQVNGKLRDTILADVNIPKEELEKIA  834
            LW A  ++ E+ +++ +WP Y E    E+ +++VVQ++GK++  ++   ++++EEL+ +A
Sbjct  744  LWQALTASGESISYV-PWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVA  802

Query  835  LASEKAQ  841
            LA+EK Q
Sbjct  803  LANEKVQ  809

1088) N646_2881 in NC_022349


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  546 bits (2059),  Expect = 4e-156, Method: Compositional matrix adjust.
 Identities = 371/868 (43%), Positives = 563/868 (65%), Gaps = 53/868 (6%)

Query  5    YNPQDIEQKVQKHWDDNKTFVVSEDPNKEKFYCLSMFPYPSGR-LHMGHVRNYTIGDVVS  63
            Y+   IE K Q  W DN TF  + D++K KFY L MFPYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RFQRLQGKNVMQPIGWDAFGLPAENAAVKNKTAPAPWTYENIEYMKNQLKLLGFGYDWNR  123
            RF+R QG NV++P+GWDAFGLPAE+ A+     PA  T ENI   K Q++ LGF+YDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EFATCTPEYYRWEQEFFTKLYEKGLVYKKTSSVNWCPNDQTVLANEQV-EDGCCWRCDTP  182
            E  T  P+YY+W Q +FTKLYEKGL Y    +VNW  +  T +ANE+V  DG   R + P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VEQKEIPQWFIKITEYAQELLDDLDKLEGWPEMVKTMQRNWIGRSEGVELKFEVKG-QQD  241
            V +K + QW +KIT YA+ LL+DL+ ++ WPE +K MQRNWIG+S G ++ F VK+ ++D
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  242  LEVYTTRPDTLMGVTYVGIaaghplaalaaennpelaaFIDECKNNKVAEAELA----TM  297
            + V+TTRPDTL G TY  +A+ H+L    + ++   A  + + K +    ++LA    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEA--VADYKRQASLKSDLARTDLAK  300

Query  298  EKKGMATGLTAIHPLNGREVPVYVANFVLMDYGTGAVMAVPAHDQRDYEFATKYGLDIVP  357
            EK G+ TG  AI+P+NG+E+PV +A++VL  YGTGA+MAVPAHD+RD EFA ++ LDI+P
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  358  VIKPADGSELDISEAAYTEKGVLFDSGEFDGLEFQAAFDAIAAKLEAEGKGTKTVNFRLR  417
            V+  +     ++ EAA+TE G+ ++S+ +DGL+  +A+  +   LEAEG G   V +RLR
Sbjct  361  VLEGG-----NVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  418  DWGVSRQRYWGAPIPMVTTEDGEVHPVPADQLPVILP--EDVVMDGVT-SPIKADKEWAK  474
            DW  SRQRYWG PIP++  EDG   +VP  +LP++LP   D+   G   SP+    +W  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  475  TTF-NGEPALRETDTFDTFMESSWYYARYCSPQADDIL-DPEKANYWLPVDQYIGGIEHA  532
             T  +G  + RET+T      SSWYY RY  P+  + L D E  + WLPVD Y+GG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  533  CMHLLYSRFFHKLLRDAGYVTSDEPFKQLLCQGMVLADAFYFENEKGGKEWVAPTDVAVE  592
             +HLLY+RF HK+L D G V + EPF++L+ QGM+L+ +  + + +G+   + +TD    
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS--YRDSRGA---LVATDKVEK  590

Query  593  RDGK-GRITSAKDTEGRDVTHSGMIKMSKSKNNGIDPQEMVDKYGADTVRLFMMFASPAD  651
            RDG   ++ ++ + E       +  KMSKS +N ++P+++V++YGADT+R++ MF +P D
Sbjct  591  RDGSFFHVETGEELE------QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLD  644

Query  652  MTLEWQESGVEGANRFLKRVWKLVKEHTAKGAAEAVDTSALSGDQKALRRDVHKTIAKVT  711
             ++ W E G+EG+ +FL RV +L+   T+K  +E         +  AL +  + T+  VT
Sbjct  645  ASIAWSEEGLEGSRKFLDRVYRLI---TTKEITEE--------NSGALDKVYNETVKAVT  693

Query  712  DDIARRQTFNTAIAAIMELMNKLAKAPQESAQDRAILDEALKAIVVMLYPITPHISYELW  771
            +++ + + FNTAIA +M ++N        + ++  ++ +  K++V ++ P++PH++ ELW
Sbjct  694  EQVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELW  745

Query  772  AALGETD--IDNAAWPTFDEKALVEDEKTIVVQVNGKLRAKLTVPADISKDDIEQLGLND  829
             AL  ++  I   +WP++DE  LVE++  IVVQ++GK++AKL V+ D+S++++++++L +
Sbjct  746  QALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALAN  805

Query  830  ENVVKFTDGLTIRKVIYVPGKLLNIVAN  857
            E+V     G  I KVI VP KL+NIV +
Sbjct  806  EKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

1089) leuS in NC_007356


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  545 bits (2058),  Expect = 4e-156, Method: Compositional matrix adjust.
 Identities = 350/849 (42%), Positives = 538/849 (64%), Gaps = 59/849 (6%)

Query  5    YNPQETEKKWQDKWAADRLYHASEDSPKPKWYSLTMFPYTSG-NLHIGHWYAEVPADCFA  63
            Y+    E KWQ  WA ++ + ++ D++KPK Y+L MFPY SG  LH+GH  +  ++D ++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYKRLRGFNVMRPVGFDSFGLPAENAAIKHNIHPRIWTLNNVENMRRQLKTIGAMFDWDR  123
            R+KR +G NV++P+G D+FGLPAE+ A+    +P   T +N+ N +RQ++++G  +DWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVITCLPEYYKWTQWFFLKLYEAGLAYRAKAPVNWCPSCQAVLANEQVV-DGTCWRCETP  182
            EV T  P+YYKWTQW+F KLYE GLAY A  PVNW     + +ANE+V+ DGT  R   P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  TTRRDLEQWFFRITNYADEL-KDHEGLDWPEKITAMQRNWVGKSYGAEVSFALDCPTAFE  241
              R+ + QW ++IT YA+ L  D E +DWPE I  MQRNW+GKS GA+V+F +      +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDT---D  240

Query  242  KEIKVFTTRPDTIYGVTFMVLAPEHPLVEKITTPENKAAVDAYIKKSRTCTEIERLSTER  301
            K++ VFTTRPDT++G T+ VLAPEH+LV+ ITT+++  AV  Y +++   +++ R    +
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  302  EKDGVFTGTYVTNRVNGQKVPVWIGDYVLQSYGTGAVMGVPAHDERDFVFAQKYHLPVIT  361
            EK GV TG+Y  N VNG+ +PVWI+DYVL SYGTGA+M+VPAHDERD  FA++++L +I 
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  362  VIAPSEYDGKPLEVAYINEGVMLNSGPFNGTPNTEGKEKVCDYLAEHGWGKKTVNYKLRD  421
            V+  ++ +    E A+ ++G+ +NS+ ++G  ++ +  K+ + L  +G G+  V Y+LRD
Sbjct  361  VLEGGNVE----EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  422  WLISRQRYWGAPIPMVYCEKCGIVPVPEKDLPVLLPEDVEFRSG--GESPLKYNEGFVNT  479
            WL+SRQRYWG PIP++  E     +VPE +LP++LP   ++R++  GESPL    + ++ 
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE-  475

Query  480  ICPVCGGKAKRETDTMDTFMCSSWYFLRYTSPGYDKGPFDPVKLKYWMPVDLYTGGAEHA  539
            +    G K++RET+TM     SSWY+LRY  P       D   LK W+PVD+Y GGAEHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  540  VMHLFYSRFFTKALRDMGIIDFGEPFKKLFNQGIIVSN----------------------  577
            V+HL+Y+RF  K L D+G++   EPF+KLFNQG+I++                       
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSF  595

Query  578  ------------HQKMSKSKGNVVTPDNLVAEVGTDAVRAYLMFVGPWDQGGEWNDSGLS  625
                          KMSKS  NVV PD++V + G+D++R Y MF+GP D +  W++ GL 
Sbjct  596  FHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLE  655

Query  626  GMSRWLNRVWNLFTEEYTPQTASAEAERELKRTLHQTIKKITMDIERLRFNTVVAALMEL  685
            G  + L+RV  L+    T +  + E    L +  ++T+K +T ++++++FNT +A LM +
Sbjct  656  GSRKFLDRVYRLI----TTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVF  711

Query  686  SNSLAKLKETAAISAENWQNTLQTFALMLAPVAPHIAEELWANLGMK-YSIHNQNWPTWD  744
             N+  K             +  + F  ++AP APH++EELW  L     SI    WP+ D
Sbjct  712  VNAANK-------EDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYD  764

Query  745  EELAKDEVITLIIQVNGKLRERLEMPAGISEAEAKETALNSERVKPHLLGKTPVTVIYVP  804
            E    ++ + +++Q++GK++ +L ++ ++S  E +E AL +E+V++++ GK  + VI VP
Sbjct  765  ESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVP  824

Query  805  GKLVNIVVK  813
             KLVNIV+K
Sbjct  825  NKLVNIVIK  833

1090) leuS in NC_020386


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  545 bits (2058),  Expect = 4e-156, Method: Compositional matrix adjust.
 Identities = 352/849 (42%), Positives = 540/849 (64%), Gaps = 59/849 (6%)

Query  5    YNPQETEKKWQDKWAADRLYHASEDSPKPKWYSLTMFPYTSG-NLHIGHWYAEVPADCFA  63
            Y+    E KWQ  WA ++ + ++ D++KPK Y+L MFPY SG  LH+GH  +  ++D ++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYKRLRGFNVMRPVGFDSFGLPAENAAIKHNIHPRIWTLNNVENMRRQLKTIGAMFDWDR  123
            R+KR +G NV++P+G D+FGLPAE+ A+    +P   T +N+ N +RQ++++G  +DWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVITCLPEYYKWTQWFFLKLYEAGLAYRAKAPVNWCPSCQAVLANEQVV-DGTCWRCETP  182
            EV T  P+YYKWTQW+F KLYE GLAY A  PVNW     + +ANE+V+ DGT  R   P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  TTRRDLEQWFFRITNYADEL-KDHEGLDWPEKITAMQRNWVGKSYGAEVSFALDCPTAFE  241
              R+ + QW ++IT YA+ L  D E +DWPE I  MQRNW+GKS GA+V+F +      +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDT---D  240

Query  242  KEIKVFTTRPDTIYGVTFMVLAPEHPLVEKITTPENKAAVDAYIKKSRTCTEIERLSTER  301
            K++ VFTTRPDT++G T+ VLAPEH+LV+ ITT+++  AV  Y +++   +++ R    +
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  302  EKDGVFTGTYVTNRVNGQKVPVWIGDYVLQSYGTGAVMGVPAHDERDFVFAQKYHLPVIT  361
            EK GV TG+Y  N VNG+ +PVWI+DYVL SYGTGA+M+VPAHDERD  FA++++L +I 
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  362  VIAPSAYDGKPLEAAYINEGVMLNSGPFNGTPNTEGKEKVCDYLAEHGWGKKTVNYKLRD  421
            V+     +G+  EAA+ ++G+ +NS+ ++G  ++ +  K+ + L  +G G+  V Y+LRD
Sbjct  361  VLE----GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  422  WLISRQRYWGAPIPMVYCEKCGIVPVPEKDLPVLLPEDVGFRSG--GESPLKYNEGFVNT  479
            WL+SRQRYWG PIP++  E     +VPE +LP++LP   ++R++  GESPL    + ++ 
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE-  475

Query  480  ICPVCGGKAKRETDTMDTFMCSSWYFLRYTSPGYDKGPFDPVKLKYWMPVDLYTGGAEHA  539
            +    G K++RET+TM     SSWY+LRY  P       D   LK W+PVD+Y GGAEHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  540  VMHLFYSRFFTKALRDMGIIDFGEPFKKLFNQGIIVSN----------------------  577
            V+HL+Y+RF  K L D+G++   EPF+KLFNQG+I++                       
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSF  595

Query  578  ------------HQKMSKSKGNVVTPDNLVAEVGTDAVRAYLMFVGPWDQGGEWNDSGLS  625
                          KMSKS  NVV PD++V + G+D++R Y MF+GP D +  W++ GL 
Sbjct  596  FHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLE  655

Query  626  GMSRWLNRVWNLFTEEYTPQTASAEAERELERTLHQTTKKITMDIERLRFNTVVAALMEL  685
            G  + L+RV  L+    T +  + E    L++  ++T K +T ++++++FNT +A LM +
Sbjct  656  GSRKFLDRVYRLI----TTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVF  711

Query  686  SNSLAKLKETAAISAENWQNTLQTFALMLAPVAPHIAEELWANL-GMEYSIHNQNWPTWD  744
             N+  K             +  + F  ++AP APH++EELW  L +   SI    WP+ D
Sbjct  712  VNAANK-------EDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYD  764

Query  745  EELAKDEVITLIIQVNGKLRERLEMPAGISEAEAKETALNSERVKPHLLGKTPVTVIYVP  804
            E    ++ + +++Q++GK++ +L ++ ++S  E +E AL +E+V++++ GK  + VI VP
Sbjct  765  ESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVP  824

Query  805  GKLVNIVVK  813
             KLVNIV+K
Sbjct  825  NKLVNIVIK  833

1091) Marme_3045 in NC_015276


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  545 bits (2056),  Expect = 5e-156, Method: Compositional matrix adjust.
 Identities = 365/856 (43%), Positives = 549/856 (65%), Gaps = 71/856 (8%)

Query  5    YNPQQIEQAAQTFWDENKVFKAVADTTKEKYYCLSMFPYPSGR-LHMGHVRNYTIGDVIS  63
            Y+   IE   Q+FW +N  FK+ +D++K K+Y L MFPYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPMGWDAFGMPAENAAIKNKTAPAKWTTENIAYMKGQLKQLGFGYDWDR  123
            R++R  G NVL+PMGWDAFG+PAE+ A+     PA  T+ENIA  K Q++ LGF+YDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EIATCTPEYYKWEQWFFTQLVEKGLAYKKTSAVNWDPVDQTVLANEQVI-DGCGWRSGAP  182
            E+ T  P+YYKW QW+FT+L EKGLAY    +VNW     T +ANE+V+ DG + R+G P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VVRKEIPQWFIKITDYAEELLNDLDQLDGWPDKVKAMQRNWIGRSEGLEFSFAVEGKEER  242
            VVRK + QW +KIT YAE LL+DL+++D WP+ +K MQRNWIG+S G + +F V + +  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LSVYTTRPDTLMGVTYVAVAATHPL--ALEAAETNSALSEFIDESK-NTSTTEADLATVE  299
            ++V+TTRPDTL G TY  +A+ H+L  A+ +++   A++++  ++  ++  + +DLA  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK-E  301

Query  300  KKGMDTGFKAIHPITGESVPVFAANFVLMEYGSGAVMSVPAHDQRDFEFAQQYNLPIKQV  359
            K G+ TG  AI+P+ G  +PV  A++VL  YG+GA+M+VPAHD+RD EFA+Q+NL I  V
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  360  VAPAGDQEIDLTKEAFTEKGLLCNSGEFDGLDFKAAFDAICAWMTDKGIGEKKVNYRLRD  419
            +  +  +E      AFTE GL  NS+ +DGLD  +A+  +  W+   G+G+ +V YRLRD
Sbjct  362  LEGGNVEE-----AAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGTPIPTINLEDGTVVTTPVDQLPVILPT--DVVMDGV-NSPIKNNPD-FSA  475
            W  SRQRYWG PIP I+ EDGT  + P  +LP++LP   D+   G  +SP+ N  D +  
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  476  TTYNGVAAERETDTFDTFMESSWYFARYCCPEADDAMLTEE-ANYWLPVDQYIGGVEHAI  534
            T  +GV + RET+T      SSWY+ RY  P+  + +  EE  + WLPVD Y+GG EHA+
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  535  LHLLYARFFHKLLRDAGLVTSDEPFKRLLTQGMV-------------------NKDGS--  573
            LHLLYARF HK+L D G+V + EPF++L+ QGM+                   ++DGS  
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFF  596

Query  574  -------------KMSKSKGNTVDPQEMIEQYGADTVRLFMMFTAPPEQSLEWNDKGVDG  620
                         KMSKS  N V+P++++EQYGADT+R++ MF +P + S+ W++ G++G
Sbjct  597  HVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEG  656

Query  621  ASRFLRRLWSLSYQHLNAGDKVALDVDALSGEQKALRRKTHETIAKVSDDIERRQTFNTA  680
            + +FL R+    Y+ + + +           +  AL +  +ET+  V++++++ + FNTA
Sbjct  657  SRKFLDRV----YRLITTKEITE-------ENSGALDKVYNETVKAVTEQVDQMK-FNTA  704

Query  681  IAAVMELCNEISKFEDRSEQGlaverealeaailllSPIVPHVAHELWGKFGHEGNVVN-  739
            IA +M + N  +K ED+      +  +   + + L++P+ PH+++ELW  +   G+ ++ 
Sbjct  705  IAQLMVFVNAANK-EDK------LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISY  757

Query  740  ATWPTVDEAALVKDELTIVVQVLGKKRAEILVSAKADNKEIEALALANPNVQKFIEGKTV  799
              WP+ DE+ LV +++ IVVQ+ GK +A ++V+      E++ +ALAN +VQ  I GK +
Sbjct  758  VPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDI  817

Query  800  RKVIVVPGRLVNIVAN  815
             KVI VP +LVNIV +
Sbjct  818  IKVIAVPNKLVNIVIK  833

1092) DehaBAV1_0159 in NC_009455


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  545 bits (2057),  Expect = 5e-156, Method: Compositional matrix adjust.
 Identities = 352/849 (42%), Positives = 539/849 (64%), Gaps = 59/849 (6%)

Query  5    YNPQETEKKWQDKWAADRLYHASEDSPKPKWYSLTMFPYTSG-NLHIGHWYAEVPADCFA  63
            Y+    E KWQ  WA ++ + ++ D++KPK Y+L MFPY SG  LH+GH  +  ++D ++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYKRLRGFNVMRPVGFDSFGLPAENAAIKHNIHPRIWTLNNVENMRRQLKTIGAMFDWDR  123
            R+KR +G NV++P+G D+FGLPAE+ A+    +P   T +N+ N +RQ++++G  +DWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVITCLPEYYKWTQWFFLKLYEAGLAYRAKAPVNWCPSCQAVLANEQVV-DGTCWRCETP  182
            EV T  P+YYKWTQW+F KLYE GLAY A  PVNW     + +ANE+V+ DGT  R   P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  TTRRDLEQWFFRITNYADEL-KDHEGLDWPEKITAMQRNWVGKSYGAEVSFALDCPTAFE  241
              R+ + QW ++IT YA+ L  D E +DWPE I  MQRNW+GKS GA+V+F +      +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDT---D  240

Query  242  KEIKVFTTRPDTIYGVTFMVLAPEHPLVEKITTPENKAAVDAYIKKSRTCTEIERLSTER  301
            K++ VFTTRPDT++G T+ VLAPEH+LV+ ITT+++  AV  Y +++   +++ R    +
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  302  EKDGVFTGTYVTNRVNGQKVPVWIGDYVLQSYGTGAVMGVPAHDERDFVFAQKYHLPVIT  361
            EK GV TG+Y  N VNG+ +PVWI+DYVL SYGTGA+M+VPAHDERD  FA++++L +I 
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  362  VIAPSAYDGKPLEAAYINEGVMLNSGPFNGTPNTEGKEKVCDYLAEHGWGKKTVNYKLRD  421
            V+     +G+  EAA+ ++G+ +NS+ ++G  ++ +  K+ + L  +G G+  V Y+LRD
Sbjct  361  VLE----GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  422  WLISRQRYWGAPIPMVYCEKCGIVPVPEKDLPVLLPEDVGFRSG--GESPLKYNEGFVNT  479
            WL+SRQRYWG PIP++  E     +VPE +LP++LP   ++R++  GESPL    + ++ 
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE-  475

Query  480  ICPVCGGKAKRETDTMDTFMCSSWYFLRYTSPGYDKGPFDPVKLKYWMPVDLYTGGAEHA  539
            +    G K++RET+TM     SSWY+LRY  P       D   LK W+PVD+Y GGAEHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  540  VMHLFYSRFFTKALRDMGIIDFGEPFKKLFNQGIIVSN----------------------  577
            V+HL+Y+RF  K L D+G++   EPF+KLFNQG+I++                       
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSF  595

Query  578  ------------HQKMSKSKGNVVTPDNLVAEVGTDAVRAYLMFVGPWDQGGEWNDSGLS  625
                          KMSKS  NVV PD++V + G+D++R Y MF+GP D +  W++ GL 
Sbjct  596  FHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLE  655

Query  626  GMSRWLNRVWNLFTEEYTPQTASAEAERELKRTLHQTIKKITMDIERLRFNTVVAALMEL  685
            G  + L+RV  L+    T +  + E    L +  ++T+K +T ++++++FNT +A LM +
Sbjct  656  GSRKFLDRVYRLI----TTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVF  711

Query  686  SNSLAKLKETAAISAENWQNTLQTFALMLAPVAPHIAEELWANLGMK-YSIHNQNWPTWD  744
             N+  K             +  + F  ++AP APH++EELW  L     SI    WP+ D
Sbjct  712  VNAANK-------EDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYD  764

Query  745  EELAKDEVITLIIQVNGKLRERLEMPAGISEAEAKETALNSERVKPHLLGKTPVTVIYVP  804
            E    ++ + +++Q++GK++ +L ++ ++S  E +E AL +E+V++++ GK  + VI VP
Sbjct  765  ESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVP  824

Query  805  GKLVNIVVK  813
             KLVNIV+K
Sbjct  825  NKLVNIVIK  833

1093) leuS in NC_002940


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  545 bits (2056),  Expect = 6e-156, Method: Compositional matrix adjust.
 Identities = 357/868 (42%), Positives = 575/868 (67%), Gaps = 50/868 (5%)

Query  5    YNPSAIESKVQHFWEENKVFKAVKDITKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIS  63
            Y+ +AIE+K Q FW +N  FK+  D +K K+Y L M+PYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMIGKNVLQPMGWDAFGLPAEGAAVKNNTAPAKWTYENIEYMKNQLKVLGFSYDWDR  123
            R++R  G NVL+PMGWDAFGLPAE  A+     PA  T ENI   K Q++ LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EITTCRPEYYKWEQWFFTELYKKGLVYKKTSTVNWCPNDETVLANEQV-HEGCCWRCDTP  182
            E+ T  P+YYKW QW+FT LY KGL Y     VNW  +  T +ANE+V  +G   R + P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VEQRDIPQWFIKITDYAEELLTQLDNLTQWPDQVKTMQRNWIGRSEGVEITFKIAGSNAT  242
            V ++ + QW +KIT YAE LL +L+++ +WP+ +K MQRNWIG+S G ++TFK+ +++  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LPVYTTRPDTFFGVSYlavaaahplaelaSTNNP--ALAEFIREAK-NTKVAEAELATME  299
            + V+TTRPDT+FG +Y  +A+ H+L +  +T++   A+A++ R+A  ++ +A ++LA  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGMPTGLFAIHPLTGKEIPVWVANFVLMHYGTGAVMAVPAHDERDFDFAKKYGLQINQV  359
            K G+ TG +AI+P+ GKE+PVW+A++VL  YGTGA+MAVPAHDERD +FAK++ L+I   
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDI---  358

Query  360  IQPLDASTWDFSQAAFTEHGKLINSAEFDGLDFNHAFNAIADKLESLGVGKRQVNFRLRD  419
            I  L+++  +  +AAFTE+G  INS  +DGLD   A+  + + LE+ GVG+ +V +RLRD
Sbjct  359  IPVLEGG--NVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMMTTEQGEVVTVPLKDLPVILP--ENVVMDGV-QSPIKSDPEWAKT  476
            W  SRQRYWG PIP++  E+G   +VP  +LP++LP   ++   G  +SP+ +  +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  TYE-GQPALKETDTFDTFMESSWYYARYTCPQYHQGMLDADEANYWLPVDQYIGGIEHAT  535
            T E G  + +ET+T      SSWYY RY  P+  + + D +  + WLPVD Y+GG EHA 
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLLYFRFFHKLLRDAGILTSDEPATKLLCQGMVLADAFYYTSPTNERIWVSPTQVSLER  595
            +HLLY RF HK+L D G++ + EP  KL+ QGM+L+ ++      + R     + V+ ++
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSR----GALVATDK  587

Query  596  DEK--GRIINATDPAGHKLVHSGMTKMSKSKNNGIDPQEMVEKYGADTVRLFMMFASPAE  653
             EK  G +++    +G+ L ++  +KMSKS +N ++P+++VE+YGADT+R++ MF +P +
Sbjct  588  VEKRDGSFFHVE--TGEELEQAP-AKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLD  644

Query  654  MTLEWQESGVEGAKRFLGRVWNLVYEYVQQPATQALNALELNKAQKELRRDVHKTIAKVS  713
             ++ W E G+EG+++FL+RV  L+       +T+ +     +     L +  + T+  V+
Sbjct  645  ASIAWSEEGLEGSRKFLDRVYRLI-------TTKEIT----EENSGALDKVYNETVKAVT  693

Query  714  DDIGRRQTFNTAIAAIMELMNKLNKAPLESDQDKAVMAEALSAVVRMLYPITPHICFELW  773
            +++++ + FNTAIA +M ++N        ++++  + ++   + V+++ P++PH+  ELW
Sbjct  694  EQVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELW  745

Query  774  QAL-GNQQTIDFAPWVVSDETAMIEDEKLVVVQVNGKVRGKITVPANASEDEVKITAKND  832
            QAL ++ ++I + PW   DE+ ++E++  +VVQ++GKV++K+ V+ + S +E++  A  +
Sbjct  746  QALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALAN  805

Query  833  ANVAKFLADMQIVKEIYIPFKMLNFVVK  860
             +V   +A+ +I+K I +P K++N+V+K
Sbjct  806  EKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

1094) leuS in NC_015859


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  544 bits (2052),  Expect = 1e-155, Method: Compositional matrix adjust.
 Identities = 355/744 (48%), Positives = 499/744 (68%), Gaps = 59/744 (7%)

Query  210  EHRLVYRSNSTVNWCPGLGTVLANEEVTADGRSERGNFPVFRKRLSQWMMRITAYSDRLI  269
            E  L Y ++  VNW   LGT +ANEEV +DG SERG +PV RK + QWM++ITAY++RL+
Sbjct  145  EKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLL  204

Query  270  DDLADLDWPEKVKSMQRNWIGRSRGAEVDFAVELAAPKSEARIRVFTTRPDTLFGASYMV  329
            +DL ++DWPE +K MQRNWIG+S GA+V F V      ++  + VFTTRPDTLFGA+Y V
Sbjct  205  EDLEEVDWPESIKDMQRNWIGKSTGANVTFKVK----DTDKDFTVFTTRPDTLFGATYAV  260

Query  330  LAPEHELVDALVTDAPYAEGTNPAWTYGEASPKDAVASYRTAIAAKSDLERQE-NKEKTG  388
            LAPEH LVDA+ T                +   +AVA Y+   + KSDL R +  KEKTG
Sbjct  261  LAPEHALVDAITT----------------SDQAEAVADYKRQASLKSDLARTDLAKEKTG  304

Query  389  VFTGAYATNPVNGAQVPVFIADYVLTGYGTGAIMAVPAHDDRDHEFATVFGLPIHEVVSG  448
            V TG+YA NPVNG ++PV IADYVL++YGTGAIMAVPAHD+RD EFA  F L I  V+ G
Sbjct  305  VWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEG  364

Query  449  GDDVQNAAYTGDGVLVNSTNDRGLSLDGKTKAEAIEATIAWLAEQGVGEEKIQYKLRDWL  508
            G +V++AA+T DG+ +NS       LDG  KA AI   + WL  +GVG+E++ Y+LRDWL
Sbjct  365  G-NVEEAAFTEDGLHINSD-----FLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWL  418

Query  509  FARQRYWGEPFPIVYDADGVAHALPESMLPVELPEVEDYKPVSFDPDDASTEPQPPLAKA  568
            F+RQRYWGEP+PI+   DG + A+PES LP+ LP   D +P        S   ++PLA+ 
Sbjct  419  FSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANV  470

Query  569  KEWVEVRLDLGDGEQTYWRDTNVMPQWAGSSWYQLRYIDPTNSDALVDIENEKYWTGPRE  628
             +W+EV  + G   +   R+TN MPQWAGSSWY LRYIDP N++ L D E  K W     
Sbjct  471  TDWLEVTREDGVKGR---RETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQW-----  522

Query  629  GMPSGGVDLYVGGVEHAVLHLLYSRFWHKVLFDLGHVSSYEPYHRLYNQGYIQAYAYTDA  688
             +P   VD+YVGG EHAVLHLLY+RFWHKVL+DLG V++ EP+++L+NQG I + +Y D+
Sbjct  523  -LP---VDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDS  578

Query  689  RGVYVPAAEVEEKDGRFFY--NGEEVNQEYGKMGKSLKNAVSPDEICDNYGADTLRVYEM  746
            RG  V++  VE +DG FF    GEE++Q  +KM+KSLKN V+PD++ ++YGADTLRVYEM
Sbjct  579  RGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEM  638

Query  747  SMGPLDTSRPWATKDVVGAQRFLQRAWRLavdeatgdaavadtaltdddNRALHRTVAGV  806
             MGPLD+S +W+  ++ G+++FL+R  RL        +       ++  ++  + TV +V
Sbjct  639  FMGPLDASIAWSEEGLEGSRKFLDRVYRL------ITTKEITEENSGALDKVYNETVKAV  692

Query  807  RDDYANLRDNTAVAKLIEYVNYLTKAYAGASVPRDAVEPLALMLAPVAPHIAEEMWTRLG  866
             ++  +++ NTA+A+L+ +VN   K      +  D    +  ++AP APH++EE+W  L 
Sbjct  693  TEQVDQMKFNTAIAQLMVFVNAANKE---DKLFSDYAKGFVQLIAPFAPHLGEELWQALT  749

Query  867  HEG-SLAHADFPTFGEKWLVDDSVELPVQVMGKVRGRITVAVDATRDAIEAAALAEPNVV  925
              G S++    P+++E  LV++ VE+ VQ+ GKV++++ VA D +R+ ++  ALA+ +V 
Sbjct  750  ASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQ  809

Query  926  AHTEGKNIVKIIVVPGKMVNIVAK  949
            A+  GK+I+K+I VP K+VNIV K
Sbjct  810  AEIAGKDIIKVIAVPNKLVNIVIK  833


 Score =  113 bits (411),  Expect = 6e-26, Method: Compositional matrix adjust.
 Identities = 71/148 (48%), Positives = 100/148 (68%), Gaps = 10/148 (6%)

Query  20   IEARWQNTWREQGTFNAPNPVGDLADPDQTLPDDKLFVQDMFPYPSGVGLHVGHPLGYIA  79
            IE++WQ  W ++ TF++    +            K++  DMFPYPSG GLHVGHP GY A
Sbjct  9    IEPKWQAFWADNHTFKTGTDASK----------PKFYALDMFPYPSGAGLHVGHPEGYTA  58

Query  80   TDVYARYNRMLGRNVLHTLGYDAFGLPAEQYAVQTGTHPRTTTQANIDNMErqlgrlglg  139
            TD+ +R++R  G+NVLH +G DAFGLPAEQYA++TG +P   T  NI N  RQ+  LG++
Sbjct  59   TDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFS  118

Query  140  hdrrrVIATTDTDFYRWTQWIFLRIYNS  167
             D+ R + TTD ++Y+WTQWIF ++Y+ 
Sbjct  119  YDWDREVNTTDPNYYKWTQWIFTKLYEK  146

1095) leuS in NC_020134


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  544 bits (2053),  Expect = 1e-155, Method: Compositional matrix adjust.
 Identities = 371/843 (45%), Positives = 535/843 (64%), Gaps = 56/843 (6%)

Query  8    DRKWQQKWEETKLYKFDRSNLDKKLYCLEMFSYPSGANLHVGHWYNFGLTDSWARMKRMQ  67
            + KWQ  W +   +K +      K+Y L+MF+YPSGA LHVGH   +  TD  +R KR Q
Sbjct  10   EPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSRFKRAQ  69

Query  68   GYNVFHPMGFDAFGLPAENYAIKTGIHPKDSTYKNIRTMEKQLREMGATYDWDYEVITCA  127
            G NV+HPMG DAFGLPAE+YA+ TG +P + T  NI    +Q+  +G +YDWD EV T  
Sbjct  70   GHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDREVNTTD  129

Query  128  PEYYKWTQWIFLQLYKHGLAYRKKAPVNWCPSCKTVLANEQVI-DGACERCHTEVTKKDL  186
            P+YYKWTQWIF +LY  GLAY    PVNW     T +ANE+V+ DG+ ER    V +K +
Sbjct  130  PNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPM  189

Query  187  TQWFFKITAYAQELLDFLPKLDWPEKTKKIQTNWIGRSEGAEIEFKIAGSDKTLKVFTTR  246
             QW +KITAYA+ LL+ L  +DWPE  K +Q NWIG+S GA++ FK+ ++DK + VFTTR
Sbjct  190  RQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTR  249

Query  247  ADTLYGVTYVVLAPESELTDEVTTDEYREQVEEYREFARKQSEIERMSTVKEKTGVFTGG  306
            +DTL+G TY VLAPE  L D +TT +  E V +Y+  A  +S++ R    KEKTGV TG+
Sbjct  250  PDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGS  309

Query  307  YAINPVNDEKVPIWIADYVLAGYGTGCVMAVPAHDERDYEFAKKFNLPIKRVIRSKDGSP  366
            YAINPVN+  +P+WIADYVLA+YGTG +MAVPAHDERD EFAK+FNL I  V+   +G+ 
Sbjct  310  YAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL--EGGNV  367

Query  367  DELPFTEDGILVDSGEFSGMTSEQARIEIVKKLQKENMAEFKVNYRLRDWLVSRQRYWGA  426
            +E +FTEDG+ ++S+ + G+    A   +V  L+ E +++ +V YRLRDWL SRQRYWG 
Sbjct  368  EEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGE  427

Query  427  PIPIIYCDDCGIvpvpeedlpvelpYNVEFTPD--GESPLAKCEEFMNTTCPKCGKPARR  484
            PIPII  +D    +VPE +LP+ LP   ++ P   GESPLA+  + ++ T     K +RR
Sbjct  428  PIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK-GRR  486

Query  485  DPDTLDTFVCSSWYFLRYPDNHNDREPFNREWINKMLPVDKYVGGAEHAAMHLLYARFIT  544
            + +T+     SSWY+LRY D HN     + E +++ LPVD YVGGAEHA +HLLYARF  
Sbjct  487  ETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWH  546

Query  545  KALRDMGYLDFDEPFKSLVHQGTILGP---------------------------------  571
            K L D+G +   EPF+ L +QG ILG                                  
Sbjct  547  KVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEELEQ  606

Query  572  DGSRMSKSKGNTISPDDYIREYGSDVFRLYLAFGFSYTEGGPWSDDGIKAISRFVNRVER  631
              ++MSKS  N ++PDD + +YG+D +R+Y  F  +   + +WS++G+ +  +F++RV R
Sbjct  607  APAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYR  666

Query  632  LVEKFVAEKDGESSDSIGADEKELIFVQNTAIKGVTEDAEKFQFNTSVARIMELTNALYK  691
            L+          + ++ GA +K  ++  N ++K+VTE+ ++ +FNT++A++M + NA   
Sbjct  667  LI-----TTKEITEENSGALDK--VY--NETVKAVTEQVDQMKFNTAIAQLMVFVNA---  714

Query  692  YDALQVKNRKLMEEAIRNlllllAPFAPHFCEEMWEKM-GYEYSIFNQKWPTYDPKALVR  750
                  K+ KL  +  + ++ L+APFAPH+ EE+W+ + +   SI    WP+YD   LV 
Sbjct  715  ----ANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVE  770

Query  751  DTIEMAVQINGQVKYKIQVPQDADNKAVEEAALNDEKAAVYLKDKEIVKIIVVPKRLVNI  810
            + +E+ VQI+G+VK K+ V++D     ++E AL +EK    + +K+I+K+I VP++LVNI
Sbjct  771  NDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNI  830

Query  811  VVK  813
            V+K
Sbjct  831  VIK  833

1096) Clst_0595 in NC_020887


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  544 bits (2053),  Expect = 1e-155, Method: Compositional matrix adjust.
 Identities = 371/843 (45%), Positives = 535/843 (64%), Gaps = 56/843 (6%)

Query  8    DRKWQQKWEETKLYKFDRSNLDKKLYCLEMFSYPSGANLHVGHWYNFGLTDSWARMKRMQ  67
            + KWQ  W +   +K +      K+Y L+MF+YPSGA LHVGH   +  TD  +R KR Q
Sbjct  10   EPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSRFKRAQ  69

Query  68   GYNVFHPMGFDAFGLPAENYAIKTGIHPKDSTYKNIRTMEKQLREMGATYDWDYEVITCA  127
            G NV+HPMG DAFGLPAE+YA+ TG +P + T  NI    +Q+  +G +YDWD EV T  
Sbjct  70   GHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDREVNTTD  129

Query  128  PEYYKWTQWIFLQLYKHGLAYRKKAPVNWCPSCKTVLANEQVI-DGACERCHTEVTKKDL  186
            P+YYKWTQWIF +LY  GLAY    PVNW     T +ANE+V+ DG+ ER    V +K +
Sbjct  130  PNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPM  189

Query  187  TQWFFKITAYAQELLDFLPKLDWPEKTKKIQTNWIGRSEGAEIEFKIAGSDKTLKVFTTR  246
             QW +KITAYA+ LL+ L  +DWPE  K +Q NWIG+S GA++ FK+ ++DK + VFTTR
Sbjct  190  RQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTR  249

Query  247  ADTLYGVTYVVLAPESELTDEVTTDEYREQVEEYREFARKQSEIERMSTVKEKTGVFTGG  306
            +DTL+G TY VLAPE  L D +TT +  E V +Y+  A  +S++ R    KEKTGV TG+
Sbjct  250  PDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGS  309

Query  307  YAINPVNDEKVPIWIADYVLAGYGTGCVMAVPAHDERDYEFAKKFNLPIKRVIRSKDGSP  366
            YAINPVN+  +P+WIADYVLA+YGTG +MAVPAHDERD EFAK+FNL I  V+   +G+ 
Sbjct  310  YAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL--EGGNV  367

Query  367  DELPFTEDGILVDSGEFSGMTSEQARIEIVKKLQKENMAEFKVNYRLRDWLVSRQRYWGA  426
            +E +FTEDG+ ++S+ + G+    A   +V  L+ E +++ +V YRLRDWL SRQRYWG 
Sbjct  368  EEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGE  427

Query  427  PIPIIYCDDCGIvpvpeedlpvelpYNVEFTPD--GESPLAKCEEFMNTTCPKCGKPARR  484
            PIPII  +D    +VPE +LP+ LP   ++ P   GESPLA+  + ++ T     K +RR
Sbjct  428  PIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK-GRR  486

Query  485  DPDTLDTFVCSSWYFLRYPDNHNDREPFNREWINKMLPVDKYVGGAEHAAMHLLYARFIT  544
            + +T+     SSWY+LRY D HN     + E +++ LPVD YVGGAEHA +HLLYARF  
Sbjct  487  ETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWH  546

Query  545  KALRDMGYLDFDEPFKSLVHQGTILGP---------------------------------  571
            K L D+G +   EPF+ L +QG ILG                                  
Sbjct  547  KVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEELEQ  606

Query  572  DGSRMSKSKGNTISPDDYIREYGSDVFRLYLAFGFSYTEGGPWSDDGIKAISRFVNRVER  631
              ++MSKS  N ++PDD + +YG+D +R+Y  F  +   + +WS++G+ +  +F++RV R
Sbjct  607  APAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYR  666

Query  632  LVEKFVAEKDGESSDSIGADEKELIFVQNTAIKGVTEDAEKFQFNTSVARIMELTNALYK  691
            L+          + ++ GA +K  ++  N ++K+VTE+ ++ +FNT++A++M + NA   
Sbjct  667  LI-----TTKEITEENSGALDK--VY--NETVKAVTEQVDQMKFNTAIAQLMVFVNA---  714

Query  692  YDALQVKNRKLMEEAIRNlllllAPFAPHFCEEMWEKM-GYEYSIFNQKWPTYDPKALVR  750
                  K+ KL  +  + ++ L+APFAPH+ EE+W+ + +   SI    WP+YD   LV 
Sbjct  715  ----ANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVE  770

Query  751  DTIEMAVQINGQVKYKIQVPQDADNKAVEEAALNDEKAAVYLKDKEIVKIIVVPKRLVNI  810
            + +E+ VQI+G+VK K+ V++D     ++E AL +EK    + +K+I+K+I VP++LVNI
Sbjct  771  NDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNI  830

Query  811  VVK  813
            V+K
Sbjct  831  VIK  833

1097) leuS in NC_010278


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  544 bits (2052),  Expect = 1e-155, Method: Compositional matrix adjust.
 Identities = 361/866 (42%), Positives = 567/866 (66%), Gaps = 46/866 (5%)

Query  5    YNPSAIEPKVQQFWAENKVFKAVKDVTKEKYYCLSMLPYPSGK-LHMGHVRNYTIGDVVS  63
            Y+ +AIEPK Q FWA+N  FK+  D +K K+Y L M+PYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMIGKNVLQPMGWDAFGLPAEGAAVKNNTAPAKWTYENIEYMKGQLKMLGFSYDWDR  123
            R++R  G NVL+PMGWDAFGLPAE  A+     PA  T ENI   K Q++ LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVTTCRPEYYKWEQWFFTELYKKGLVYKKTSTVNWCPNDATVLANEQV-HEGCCWRCDTP  182
            EV T  P+YYKW QW+FT LY KGL Y     VNW  + +T +ANE+V  +G   R + P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VEQREIPQWFIKITDYAEELLTHLDNLPQWPDQVKTMQRNWIGRSEGVEITFKIAGSNAE  242
            V ++ + QW +KIT YAE LL +L+++ +WP+ +K MQRNWIG+S G ++TFK+ +++ +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LPVYTTRPDTFFGVSY--VaiaaahplaemaaENNPALAEFIREAK-NTKVAEAELATME  299
            + V+TTRPDT+FG +Y  +A   A   A  ++++  A+A++ R+A  ++ +A ++LA  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGMATGLFAIHPLTGKEVPVWVANFVLMHYGTGAVMAVPAHDERDFEFAQKYGLQINQV  359
            K G+ TG +AI+P+ GKE+PVW+A++VL  YGTGA+MAVPAHDERD EFA+++ L+I   
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDI---  358

Query  360  IQPLDGSEWDFSKAAYTEHGKLINSAEFDDLNFEQAFNAIADKLESMKVGKRQVNFRLRD  419
            I  L+G+  +   AA+TE+G  INS  +D+L+   A+  + + LE+  VG+ +V +RLRD
Sbjct  359  IPVLEGG--NVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMMTTEDGEVVTVPMQDLPVILP--EDVVMNGV-QSPIKADPEWAKT  476
            W  SRQRYWG PIP++  EDG   +VP  +LP++LP   D+  +G  +SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  TY-NGKPALKETDTFDTFMESSWYYARYTCPQYHEGMLDSDEANYWLPVDQYIGGIEHAT  535
            T  +G  + +ET+T      SSWYY RY  P+  E + D +  + WLPVD Y+GG EHA 
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLLYFRFFHKLLRDAGILNSDEPATKLLCQGMVLADAFYYTSPTNERIWVSPTQVTLER  595
            +HLLY RF HK+L D G++ + EP  KL+ QGM+L+ ++      + R     + V+ ++
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSR----GALVATDK  587

Query  596  DEKGRIIKATDPEGRELVHSGMTKMSKSKNNGIDPQEMVEKYGADTVRLFMMFASPAEMT  655
             EK R     + E  E ++ + +KMSKS +N ++P+++VE+YGADT+R++ MF +P + +
Sbjct  588  VEK-RDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  656  LEWQESGVEGAKRFLGRVWNLVYEYSQNPATAALDVAALSKAQKELRRDVHKTIAKVSDD  715
            + W E G+EG+++FL+R    VY        +  + +AL K  +E       T+  V+++
Sbjct  647  IAWSEEGLEGSRKFLDR----VYRLITTKEITEENSGALDKVYNE-------TVKAVTEQ  695

Query  716  IGRRQTFNTAIAAIMELMNKLTKAPLENEQDKAVMAEALSAVVRMLYPITPHICFELWQA  775
            +++ + FNTAIA +M ++N         +++  + ++   + V+++ P++PH+  ELWQA
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  776  L-GNNDTIDFAPWVVADESAMVEDEKLVVVQVNGKVRGKVTVSATATEDEVKAIAKADAN  834
            L ++ ++I + PW   DES +VE++  +VVQ++GKV++K+ V+   + +E++ +A A+ +
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  835  VAKFLEGVEIVKEIYVPYKMLSFAVK  860
            V   + G +I+K I VP K++++ +K
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVIK  833

1098) leuS in NC_009053


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  544 bits (2052),  Expect = 1e-155, Method: Compositional matrix adjust.
 Identities = 361/866 (42%), Positives = 567/866 (66%), Gaps = 46/866 (5%)

Query  5    YNPSAIEPKVQQFWAENKVFKAVKDVTKEKYYCLSMLPYPSGK-LHMGHVRNYTIGDVVS  63
            Y+ +AIEPK Q FWA+N  FK+  D +K K+Y L M+PYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMIGKNVLQPMGWDAFGLPAEGAAVKNNTAPAKWTYENIEYMKGQLKMLGFSYDWDR  123
            R++R  G NVL+PMGWDAFGLPAE  A+     PA  T ENI   K Q++ LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVTTCRPEYYKWEQWFFTELYKKGLVYKKTSTVNWCPNDATVLANEQV-HEGCCWRCDTP  182
            EV T  P+YYKW QW+FT LY KGL Y     VNW  + +T +ANE+V  +G   R + P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VEQREIPQWFIKITDYAEELLTHLDNLPQWPDQVKTMQRNWIGRSEGVEITFKIAGSNAE  242
            V ++ + QW +KIT YAE LL +L+++ +WP+ +K MQRNWIG+S G ++TFK+ +++ +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LPVYTTRPDTFFGVSY--VaiaaahplaemaaENNPALAEFIREAK-NTKVAEAELATME  299
            + V+TTRPDT+FG +Y  +A   A   A  ++++  A+A++ R+A  ++ +A ++LA  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGMATGLFAIHPLTGKEVPVWVANFVLMHYGTGAVMAVPAHDERDFEFAQKYGLQINQV  359
            K G+ TG +AI+P+ GKE+PVW+A++VL  YGTGA+MAVPAHDERD EFA+++ L+I   
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDI---  358

Query  360  IQPLDGSEWDFSKAAYTEHGKLINSAEFDDLNFEQAFNAIADKLESMKVGKRQVNFRLRD  419
            I  L+G+  +   AA+TE+G  INS  +D+L+   A+  + + LE+  VG+ +V +RLRD
Sbjct  359  IPVLEGG--NVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMMTTEDGEVVTVPMQDLPVILP--EDVVMNGV-QSPIKADPEWAKT  476
            W  SRQRYWG PIP++  EDG   +VP  +LP++LP   D+  +G  +SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  TY-NGKPALKETDTFDTFMESSWYYARYTCPQYHEGMLDSDEANYWLPVDQYIGGIEHAT  535
            T  +G  + +ET+T      SSWYY RY  P+  E + D +  + WLPVD Y+GG EHA 
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLLYFRFFHKLLRDAGILNSDEPATKLLCQGMVLADAFYYTSPTNERIWVSPTQVTLER  595
            +HLLY RF HK+L D G++ + EP  KL+ QGM+L+ ++      + R     + V+ ++
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSR----GALVATDK  587

Query  596  DEKGRIIKATDPEGRELVHSGMTKMSKSKNNGIDPQEMVEKYGADTVRLFMMFASPAEMT  655
             EK R     + E  E ++ + +KMSKS +N ++P+++VE+YGADT+R++ MF +P + +
Sbjct  588  VEK-RDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  656  LEWQESGVEGAKRFLGRVWNLVYEYSQNPATAALDVAALSKAQKELRRDVHKTIAKVSDD  715
            + W E G+EG+++FL+R    VY        +  + +AL K  +E       T+  V+++
Sbjct  647  IAWSEEGLEGSRKFLDR----VYRLITTKEITEENSGALDKVYNE-------TVKAVTEQ  695

Query  716  IGRRQTFNTAIAAIMELMNKLTKAPLENEQDKAVMAEALSAVVRMLYPITPHICFELWQA  775
            +++ + FNTAIA +M ++N         +++  + ++   + V+++ P++PH+  ELWQA
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  776  L-GNNDTIDFAPWVVADESAMVEDEKLVVVQVNGKVRGKVTVSATATEDEVKAIAKADAN  834
            L ++ ++I + PW   DES +VE++  +VVQ++GKV++K+ V+   + +E++ +A A+ +
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  835  VAKFLEGVEIVKEIYVPYKMLSFAVK  860
            V   + G +I+K I VP K++++ +K
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVIK  833

1099) leuS in NC_008260


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  544 bits (2052),  Expect = 1e-155, Method: Compositional matrix adjust.
 Identities = 359/855 (42%), Positives = 538/855 (63%), Gaps = 69/855 (8%)

Query  12   YRPDQIEAQAQQYWDDNQSFKVTEDASKEKFYCLSMFPYPSGR-LHMGHVRNYSIGDVVS  70
            Y    IE++ Q +W DN++FK   DASK KFY L MFPYPSG  LH+GH   Y+  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  71   RYQRMLGKNVLQPMGWDAFGLPAENAAIKNKVAPAKWTFENIDYMRGQLQRLGFGYDWGR  130
            R++R  G NVL+PMGWDAFGLPAE+ A+     PA  T ENI   + Q++ LGF+YDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  131  ELATCTPEYYRWEQWFFTKLYEKGLVYRKMSTVNWDPVDQTVLANEQVI-DGRGWRSGAL  189
            E+ T  P+YY+W QW+FTKLYEKGL Y     VNW     T +ANE+V+ DG + R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  190  VEQKEIPQWFIKITDYADELLNDLDQLDGWPEQVKTMQRNWIGRSEGVELDFPI-EGEES  248
            V +K + QW +KIT YA+ LL+DL+++D WPE +K MQRNWIG+S G ++ F + + +  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  249  LRVYTTRPDTLMGVSYVAVAAGHPLAQKAAAANH--EVADFIKECQNTKTAEADMATMEK  306
            + V+TTRPDTL G +Y  +A+ H+L +  +++++   VAD+ ++            + EK
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEK  302

Query  307  KGIYTGLTATHPISGEAVPVWIANFVLMGYGTGAVMAVPAHDQRDFEFAQKYGLPINQVI  366
             G+ TG  A +P++G  +PVWIA++VL +YGTGA+MAVPAHD+RD EFA+++ L I  V+
Sbjct  303  TGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL  362

Query  367  EPANGEPIDLALEAFTGKGTLIHSGEFDGLSSAEAFNAIANWLSERSLGEKKVNYRLRDW  426
            E +N E       AFT  G  I+S+ +DGL  A A+  + +WL   ++G+ +V YRLRDW
Sbjct  363  EGGNVEE-----AAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDW  417

Query  427  GVSRQRYWGTPIPMVETEDGTLHPTPEDQLPVALPTDVEM---DGVTSPIKADPEWAKTT  483
              SRQRYWG PIP+++ EDGT  + PE +LP+ LP   ++   +   SP+    +W   T
Sbjct  418  LFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT  477

Query  484  F-NGQPALRETDTFDTFMESSWYYARYCSPQSDTAMLDPAATNYWLPVDQYIGGIEHAIL  542
              +G  + RET+T      SSWYY RY  P++   + D    + WLPVD Y+GG EHA+L
Sbjct  478  REDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVL  537

Query  543  HLLYSRFFHKLLRDTGLVNCDEPFKQLLCQGMVL-------------------KDG----  579
            HLLY+RF HK+L D G+V   EPF++L+ QGM+L                   +DG    
Sbjct  538  HLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFH  597

Query  580  -----------AKMSKSKGNTVDPQQMIEEYGADTVRLFMMFAAPPEQSLEWNDAGVEGA  628
                       AKMSKS  N V+P++++E+YGADT+R++ MF +P + S+ W++ G+EG+
Sbjct  598  VETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGS  657

Query  629  FRFIKRLWRLVAEHVEAGNTGTLDVNALDDAGKALRRKTHETIQKVSDDYGRRNTFNTAI  688
             +F+ R+ RL++             +  ++ + AL +  +ET++ V+++ ++ + FNTAI
Sbjct  658  RKFLDRVYRLITTK-----------EITEENSGALDKVYNETVKAVTEQVDQMK-FNTAI  705

Query  689  AAVMELINEVSKFDAATDNalavkqealeaavlllaPIIPHAGHSLWQAL-GHDEAVIDA  747
            A +M ++N  +K D    +          + V L+AP+ PH G+ LWQAL + +E++   
Sbjct  706  AQLMVFVNAANKEDKLFSD-------YAKGFVQLIAPFAPHLGEELWQALTASGESISYV  758

Query  748  SWPSVDESALVKDSIELVVQVNGKVRAKLNVPANADKASVESLAMDEPNVKKFTEGKTVR  807
            +WPS DES LV + +E+VVQ++GKV+AKL V+ +  +  ++ +A+ + +V+    GK + 
Sbjct  759  PWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDII  818

Query  808  KVIVVPGKLVNIVAN  822
            KVI VP KLVNIV +
Sbjct  819  KVIAVPNKLVNIVIK  833

1100) F7308_1367 in NC_015696


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  544 bits (2052),  Expect = 1e-155, Method: Compositional matrix adjust.
 Identities = 357/861 (42%), Positives = 552/861 (65%), Gaps = 76/861 (8%)

Query  1    MSEYNFTQIEQQAQEYWRENDSFEATEDKNKEKFYCLSMLPYPSGT-LHMGHVRNYTIGD  59
            M+ Y+ T IE + Q +W +N++F +  D +K KFY L M+PYPSG+ LH+GH   YT  D
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  60   VIARYQKMQGKNVLHPMGWDAFGLPAENAAIKHKKSPYKWTKSNIAYMRSQLDSLGFSFD  119
            +++R+++ QG NVLHPMGWDAFGLPAE+ A+   + P   T  NIA  + Q+++LGFS+D
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  120  WSREIATCDENYYKWEQWFFIQLYKKGLAYRKNSVVNW-DPVDQTVLANEQVVDGRGWRS  178
            W RE+ T D NYYKW QW+F +LY KGLAY  +  VNW + ++ ++  +E + DG + R+
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  179  GALVEKKEIPQWFLKITDYADELLKDINQLDGWPEAVKTMQTNWIGKSKGLTVKFKIQNS  238
            G  V +K + QW LKIT YA+ LL D++++D WPE++K MQ NWIGKS G  V FK++++
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDT  239

Query  239  DQEIEVFTTRPDTLMGVSYLGIAPEHPLALEQAETNVELASFIEECKKLSTMEADLA---  295
            D+++ VFTTRPDTL G +Y  +APEH+L   +A T  + A  + + K+ +++ +DLA   
Sbjct  240  DKDFTVFTTRPDTLFGATYAVLAPEHALV--DAITTSDQAEAVADYKRQASLKSDLARTD  297

Query  296  -TQEKKGFKTSIKVIHPISGETVDVWVANFVLMGYGSGAVMSVPAHDQRDWEFAQKYNIA  354
             ++EK G  T+   I+P++G  + VW+A++VL +YG+GA+M+VPAHD+RDWEFA+++N+ 
Sbjct  298  LAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLD  357

Query  355  LKQVIKPSDNKSKLDLDKEAFTEKGILTNSGEFDGLNFKKAYQAMKKYLFDNNKGYETTN  414
            +  V+  +      +++  AFTE G+  NS+ +DGL+   A   M   L  +  G E   
Sbjct  358  IIPVLEGG------NVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVT  411

Query  415  FRIHDWGISRQRFWGCPIPMIHCNDCGVVPEKEENLPVKLPTNVTLTEAG---SPLKDMP  471
            +R++DW +SRQR+WG PIP+IH +D    +  E +LP+ LP    +  +G   SPL ++ 
Sbjct  412  YRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVT  471

Query  472  EFLDVACPKCGKPAKRETDTFDTFFESSWYYARYTCPTANEMLIEEA--NYWLPVDKYIG  529
            + L+V+     K ++RET+T      SSWYY RY  P   E L +E   + WLPVD Y+G
Sbjct  472  DWLEVTREDGVK-GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVG  530

Query  530  GIEHAIMHLLYARFFHKLMRDEGLITSDEPFKNLLTQGMVL-------------------  570
            G EHA++HLLYARF HK++ D G++ + EPF++L+ QGM+L                   
Sbjct  531  GAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEK  590

Query  571  KDG---------------AKMSKSKGNTVDPQELIDKYGADTVRLFSMFAAPPEQSLEWS  615
            +DG               AKMSKS  N V+P++++++YGADT+R++ MF +P + S+ WS
Sbjct  591  RDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWS  650

Query  616  ETGVDGANKFLRKVYNYAYTNKEILAKNVTIDTGVLSKNDKKARYEIYANLKQAIFD-FE  674
            E G++G+ KFL +VY    T KEI   N    +G L K        +Y +  +A+ +  +
Sbjct  651  EEGLEGSRKFLDRVYRLI-TTKEITEEN----SGALDK--------VYNETVKAVTEQVD  697

Query  675  KSQFNTVVSACMKILNTLNNYDNL-SDSVKSEGFSILLRILSPFTPHICHYLWQEIDL-G  732
            + +FNT ++  M ++N+ N+ D+L SD  K  GF   +++++PF+PH+ + LWQ +   G
Sbjct  698  QMKFNTAIAQLMVFVNAANKEDKLFSDYAK--GF---VQLIAPFAPHLGEELWQALTASG  752

Query  733  DDILHTIFPIVDEKALEKDEFLLVVQINGKVKAKLELETSLTKDQVEEVVLADEHVKNNI  792
            + I     P  DE  L  ++  +VVQI+GKVKAKL +   L++++++EV LA+E V+ +I
Sbjct  753  ESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEI  812

Query  793  EDKQIIKVIYIPQKLINIVIR  813
             +K+IIKVI +P+KL+NIVI+
Sbjct  813  AGKDIIKVIAVPNKLVNIVIK  833

1101) Glaag_2764 in NC_015497


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  544 bits (2053),  Expect = 1e-155, Method: Compositional matrix adjust.
 Identities = 364/878 (42%), Positives = 561/878 (64%), Gaps = 57/878 (6%)

Query  4    KIYEPQKIEQEVQALWETNQTFKATEQEDKEKFYCLSMFPYPSGR-LHMGHVRNYTIGDV  62
             +Y+   IE   QA+W  N+TFK+  +  K KFY L MFPYPSG  LH+GH   YT  D+
Sbjct  2    TFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDI  61

Query  63   VSRFQRMNGKNVLQPMGWDAFGLPAENAALNNNTAPAKWTYQNIDYMKNQLKSLGFGYDW  122
            +SRF+R +G NVL+PMGWDAFGLPAE+ A++    PA  T +NI   K Q+++LGF+YDW
Sbjct  62   LSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDW  121

Query  123  DREVATCKKEYYRWEQWFFTRLYEKGLVYKKNSTVNWDPVDHTVLANEQVI-DGRGWRSG  181
            DREV T   +YY+W QW+FT+LYEKGL Y  +  VNW     T +ANE+V+ DG + R+G
Sbjct  122  DREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGG  181

Query  182  ALVEQKEIPQWFIKITDYaeelladleqledWPEQVRAMQKNWIGRSEGVDITFNLSESA  241
              V +K + QW +KIT Y  E L +  +  DWPE ++ MQ+NWIG+S G ++TF++ ++ 
Sbjct  182  YPVVRKPMRQWMLKITAY-AERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  242  ADISSFDVYTTRPDTLYGVTYvavaaqhplalhaaqTRPELAEFIESCKNTKVAEAELA-  300
             D   F V+TTRPDTL+G TY         AL  A T ++ AE +   K      ++LA 
Sbjct  241  KD---FTVFTTRPDTLFGATY--AVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLAR  295

Query  301  ---TMEKKGCDTGLFAIHPLTGEKVAVWVANFVLMGYGSGAVMSVPGHDQRDWEFAQKYS  357
               + EK G  TG +AI+P+ G  ++VW+A++VL +YG+GA+M+VP+HD+RDWEFA++++
Sbjct  296  TDLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFN  355

Query  358  LPIKQVVEPSADDPQECDLTTAAYTEKGVLVNSGEFNGLAFQEAFDAIAAKLEALGAGCK  417
            L I  V+E +       ++  AA+TE G+ +NS+ ++GL    A+  +   LEA G G  
Sbjct  356  LDIIPVLEGG-------NVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNE  408

Query  418  KVNYRLRDWGVSRQRYWGSPIPMLNLENGESVPVPSDQLPVELP--EDVQMNGV-ISPIK  474
            +V YRLRDW  SRQRYWG PIP+++ E+G S +VP  +LP+ LP   D++ +G   SP+ 
Sbjct  409  NVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLA  468

Query  475  ADPEWAK-TEYNGQPAQRETDTFDTFMESSWYYARYCSAQNQDAMLDPAQANYWLPVDQY  533
               +W   T  +G  ++RET+T      SSWYY RY  ++N + + D    + WLPVD Y
Sbjct  469  NVTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIY  528

Query  534  IGGIEHAILHLLYSRFFHKLLRDEGLVSSDEPYKRLLCQGMVLADSFYREDENGKKEWFS  593
            +GG EHA+LHLLY+RF HK+L D G+V++ EP+++L+ QGM+L+ S YR+   +      
Sbjct  529  VGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS-YRDSRGAL-----  582

Query  594  PADVDTEKDEKGRITLATLRSDGKPVEHGGMTKMSKSKNNGIDPQHVIDLYGADTIRVFT  653
               V T+K EK   ++  + + G  +E++  +KMSKS +N ++P++V++ YGADT+RV+ 
Sbjct  583  ---VATDKVEKRDGSFFHVET-GEELEQAP-AKMSKSLKNVVNPDDVVEQYGADTLRVYE  637

Query  654  MFAAPPEQTLEWVDSGVEGANRFIKRVWKLTQDHIDVLNGKAAPEIDKAALTSEQKTLRR  713
            MF +P + ++ W + G+EG+ +F+ RV +L       +  K   E + +AL        +
Sbjct  638  MFMGPLDASIAWSEEGLEGSRKFLDRVYRL-------ITTKEITEENSGALD-------K  683

Query  714  AVHRTIAKVTDDVGRRQTFNTAVAAIMELLNSLQKAPQDSAQDKAVMHEAIESVVLLLNP  773
              + T+  VT++V++ + FNTA+A +M ++N+ +K       +  +  +   + V L+ P
Sbjct  684  VYNETVKAVTEQVDQMK-FNTAIAQLMVFVNAANK-------EDKLFSDYAKGFVQLIAP  735

Query  774  IAPHMCHVLWHDLGHTTD-IETAAWPEVDESALVEDEKLIIVQVNGKVRSKITVAADASQ  832
            +APH+ + LW+ L  + + I   +WP  DES LVE++  I+VQ++GKV++K+ VA D S+
Sbjct  736  FAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSR  795

Query  833  DEVQALGLAQENVQQFVEGKTIRKVIYIAGKLLNIVAN  870
            +E+Q ++LA+E+VQ  + GK I KVI ++ KL+NIV +
Sbjct  796  EELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

1102) Anae109_2719 in NC_009675


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  544 bits (2055),  Expect = 7e-156, Method: Compositional matrix adjust.
 Identities = 352/868 (41%), Positives = 543/868 (63%), Gaps = 76/868 (8%)

Query  7    YEPQSIEPRWQSRWEEAGAFRAGRRPDAEKRYVLEMFPYPSGA-MHMGHARVYTIGDALA  65
            Y+  +IEP+WQ+ W +  +F++G  +   K Y L+MFPYPSGA +H+GH+  YT  D L+
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  66   RHLRMRGHDVLHPIGFDALGLPAENAAIKDGRHPEERTRENIVAFRAEMKKLGYAFDWDR  125
            R  R +GH+VLHP+G DA+GLPAE+ A+  G +P E T ENI  F+ +++ LG+++DWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  126  EVVTADPSYYRWNQWFFLRMLELGIVYRREGKANWCTGCATVIANEQVV-DDTCERCGSP  184
            EV T+DP+YY+W QW+F ++ E G+ Y  E   NW    +T IANE+V+ D+T ER G P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  185  VVEKVIPEWAFRITAFAQDLLDGLDRLTEWPERITTMQRNWIGKSVGAEVDFILAGGRGE  244
            VV K + +W ++ITA+A+ LL++L+ + +WPE I  MQRNWIGKS GA+V F + +   +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  245  AAPPGLPIKVFTTRVDTIYGCTYVVLAPEHPLVERITVPERQAEVRAFVermrrteaaer  304
                   + VFTTR DT++G TY VLAPEH+LV+ IT +++   V  +  +        R
Sbjct  243  -------FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLAR  295

Query  305  tgeSAPKEGVFTGAHAVNPYTGEQVPVWIANFVLAEYGTGAVMSVPAHDQRDFEFARKYG  364
            T+ +  K GV TG+ A+NP  G ++PVWIA++VLA YGTGA+M+VPAHD+RD EFA+++ 
Sbjct  296  TDLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFN  355

Query  365  LPIRVVIQPAKGEKLPAGEALAQAFTEDGVLEGSGSATGLASAQAREKLAAEAQARGFGQ  424
            L I  V        L +G+    AFTEDG+   S+   GL  A A  K+    +A G G+
Sbjct  356  LDIIPV--------LEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGN  407

Query  425  PTVRWHLRDWGFSRQRYWGTPIPIVYCPDHGAVPVPEDQLPVTLP--KEAIITGTGEPPL  482
              V  +LRDW FSRQRYWG PIPI+   D  + +VPE +LP+ LP  K+   +GTGE+PL
Sbjct  408  ENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPL  467

Query  483  AKVPSFVNTTCPRCGKPARREVDTMDTFVDSSWYYARYLSPKDDTRPFDPAEAARWLPVD  542
            A+V   ++ T     K +RRE +TM    +SSWYY RY+ P +  +  D     +WLPVD
Sbjct  468  ANVTDWLEVTREDGVK-GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVD  526

Query  543  VYVGGPEHAVMHLLYFRFWHRVMHRLGLVREDEPCKRLVTQGIVNGPDGR----------  592
            +YVGG+EHAV+HLLY RFWH+V+  LG+V   EP ++L  QG++ G   R          
Sbjct  527  IYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATD  586

Query  593  -----------------------KMSKRWGNVVAPGPMVARFGADTVRLFMLFAAPPEKD  629
                                   KMSK   NVV P+ +V ++GADT+R++ +F +P +  
Sbjct  587  KVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  630  IDWSDEQVDGMFRFLARVWRIFHARQECFRAPEAALAQAQGDFLELRRRTHRTIKRVTEG  689
            I WS+E ++G  +FL RV R++ +++         +++ +++   L +  + T+K VTE 
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLITTKE---------ITEENSG--ALDKVYNETVKAVTEQ  695

Query  690  LEGELKFNTSIAALMELVNALYQLEPKSEPEQAAVREALLAVATLLAPFAPHAAEELWHE  749
            ++ ++KFNT+IA LM +VNA       ++ E+    +   +   L+APFAPH +EELW+ 
Sbjct  696  VD-QMKFNTAIAQLMVFVNA-------ANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  750  VLGPAARERLLAEAPWPSFEPALVAADVVTIAVQVNGKLRGEVQAPVAAGEAEVRALAEG  809
            + +++     ++  PWPS++ + +  + V I VQ++GK+++ +  +   +  E++ +A +
Sbjct  748  LTASGES---ISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALA  804

Query  810  EERVRAHLDGKTVRKVVFVPKRLINFVV  837
            +E+V+A++ GK + KV+ VP++L+N+V+
Sbjct  805  NEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

1103) leuS in NC_021831


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  544 bits (2054),  Expect = 8e-156, Method: Compositional matrix adjust.
 Identities = 359/842 (43%), Positives = 554/842 (66%), Gaps = 69/842 (8%)

Query  3    DHRAIEKKWQDYWYKNKVFKT-TETSRKKAYILDMFPYPSASGLHLGHPIGYTASDIVAR  61
            DH AIE KWQ +W  N  FKT T++S+ K Y LDMFPYPS++GLH+GHP GYTA+DI++R
Sbjct  5    DHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSR  64

Query  62   FKRLNGFDVLHPMGWDAFGLPAEQYAIKTGNHPGEFTKRNIENFKKQIISFGFSYDWDKE  121
            FKR +G +VLHPMGWDAFGLPAEQYA+ TGN+P+EFT  NI NFK+QI ++GFSYDWD+E
Sbjct  65   FKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDRE  124

Query  122  INTSDPEFYVQTQWIFKLLYKANLAEIREVEVNWCPELGTVLANEELKREKNGALVSERG  181
            +NT+DP++Y  TQWIF  LY   LA   EV VNW  ELGT +ANEE+  +      SERG
Sbjct  125  VNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGT----SERG  180

Query  182  NFPVILKKMKQWVLKITEYAQKLLDGLDQVDFPDSLKTLQkkwigkskgwkikFLIEKTG  241
             +PV+ K M+QW+LKIT YA++LL++L++VD P+S+K +Q++WIGKS G ++ F +  T+
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  242  EFLEIFTTKIETFYGVSFLALAPLHNFAQKLAKNNK--KISQFIEQNSFSS----PKLQS  295
              + +FTT+ +T++G ++  LAP H + + ++ +++   ++++  Q S+ S      L  
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  296  KMTGIFTGLYAIHPLNSSKIPIYIANYVLNNYATSAIMGVPGHNLADLEFAQIFQIDYVK  355
              TG+ TG YAI+P+N+  +P+ IA+YVL +Y+T+AIM+VP+H+  D EFA+ F++D + 
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  356  VIN----------QENLLINSAEFSGLTIKEGANSIFNKLNSMNLVQKTTIFRLKDWVFS  405
            V++          ++ L INS  + GL    +   + + L++  + +    +RL+DW+FS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  406  RQRYWGEPFP-VYFDEKGKIYLEEKIVE--LPHTDKIMPSGDGQSPLASIKDWVFFEK-N  461
            RQRYWGEP+P +  ++     + E  +   LP T  I PSG G+SPLA++ DW+   + +
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  462  GKYYRRETNTMPQWSGSSWYYLAFILKEKDKYLPLDSKIAYDKFKKWLPVDLYIGGQEHA  521
            G   RRETNTMPQW+GSSWYYL +I  ++   L+ +     + +K+WLPVD+Y+GG EHA
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADE-----ELLKQWLPVDIYVGGAEHA  535

Query  522  VGHLIYSRFWHKVLFDAGIVPNSEPFQKIIHQGMLLGSD---------------------  560
            V HL+Y+RFWHKVL+D G+VP  EPFQK+++QGM+LG+                      
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSF  595

Query  561  ------------GQKMSKSKGNTINPTEMIDKFGADTIRIFLMFMGPIGDLRLWDENGVV  608
                          KMSKS  N +NP ++++++GADT+R++ MFMGP++    W E+G+ 
Sbjct  596  FHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLE  655

Query  609  SIFNWIQRVQRTILADYEIDPELEKDYEFTYFFNNFVFEITNLIETFKFNVAISKLMVYI  668
            +  + ++RV R I +  EI  E     +  Y  N+ V  +T+ ++  KFN AI++LMV++
Sbjct  656  GSRKFLDRVYRLITTK-EITEENSGALDKVY--NETVKAVTEQVDQMKFNTAIAQLMVFV  712

Query  669  NFLNKKQKIPSKNYLTDFLIIFSVFAPHTAee--llekleqkplNFQIWPQFDRSKIFKN  726
            N  NK +K+ S +Y  +F+ +++ FAPH +EE          ++++  WP +D SK+  N
Sbjct  713  NAANKEDKLFS-DYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVEN  771

Query  727  TFHLPVSINGKNRGILELTDEKSQEEIIEIAKKDYKIRNYLQNKQIIKVIYIPRKILNFI  786
              ++ V I+GK ++ L ++ + S+EE+ E+A  + K++  +  K+IIKVI +P K++N++
Sbjct  772  DVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIV  831

Query  787  LK  788
            +K
Sbjct  832  IK  833

1104) leuS in NC_007332


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  544 bits (2054),  Expect = 8e-156, Method: Compositional matrix adjust.
 Identities = 359/842 (43%), Positives = 554/842 (66%), Gaps = 69/842 (8%)

Query  3    DHRAIEKKWQDYWYKNKVFKT-TETSRKKAYILDMFPYPSASGLHLGHPIGYTASDIVAR  61
            DH AIE KWQ +W  N  FKT T++S+ K Y LDMFPYPS++GLH+GHP GYTA+DI++R
Sbjct  5    DHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSR  64

Query  62   FKRLNGFDVLHPMGWDAFGLPAEQYAIKTGNHPGEFTKRNIENFKKQIISFGFSYDWDKE  121
            FKR +G +VLHPMGWDAFGLPAEQYA+ TGN+P+EFT  NI NFK+QI ++GFSYDWD+E
Sbjct  65   FKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDRE  124

Query  122  INTSDPEFYVQTQWIFKLLYKANLAEIREVEVNWCPELGTVLANEELKREKNGALVSERG  181
            +NT+DP++Y  TQWIF  LY   LA   EV VNW  ELGT +ANEE+  +      SERG
Sbjct  125  VNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGT----SERG  180

Query  182  NFPVILKKMKQWVLKITEYAQKLLDGLDQVDFPDSLKTLQkkwigkskgwkikFLIEKTG  241
             +PV+ K M+QW+LKIT YA++LL++L++VD P+S+K +Q++WIGKS G ++ F +  T+
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  242  EFLEIFTTKIETFYGVSFLALAPLHNFAQKLAKNNK--KISQFIEQNSFSS----PKLQS  295
              + +FTT+ +T++G ++  LAP H + + ++ +++   ++++  Q S+ S      L  
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  296  KMTGIFTGLYAIHPLNSSKIPIYIANYVLNNYATSAIMGVPGHNLADLEFAQIFQIDYVK  355
              TG+ TG YAI+P+N+  +P+ IA+YVL +Y+T+AIM+VP+H+  D EFA+ F++D + 
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  356  VIN----------QENLLINSAEFSGLTIKEGANSIFNKLNSMNLVQKTTIFRLKDWVFS  405
            V++          ++ L INS  + GL    +   + + L++  + +    +RL+DW+FS
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  406  RQRYWGEPFP-VYFDEKGKIYLEEKIVE--LPHTDKIMPSGDGQSPLASIKDWVFFEK-N  461
            RQRYWGEP+P +  ++     + E  +   LP T  I PSG G+SPLA++ DW+   + +
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  462  GKYYRRETNTMPQWSGSSWYYLAFILKEKDKYLPLDSKIAYDKFKKWLPVDLYIGGQEHA  521
            G   RRETNTMPQW+GSSWYYL +I  ++   L+ +     + +K+WLPVD+Y+GG EHA
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADE-----ELLKQWLPVDIYVGGAEHA  535

Query  522  VGHLIYSRFWHKVLFDAGIVPNSEPFQKIIHQGMLLGSD---------------------  560
            V HL+Y+RFWHKVL+D G+VP  EPFQK+++QGM+LG+                      
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSF  595

Query  561  ------------GQKMSKSKGNTINPTEMIDKFGADTIRIFLMFMGPIGDLRLWDENGVV  608
                          KMSKS  N +NP ++++++GADT+R++ MFMGP++    W E+G+ 
Sbjct  596  FHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLE  655

Query  609  SIFNWIQRVQRTILADYEIDPELEKDYEFTYFFNNFVFEITNLIETFKFNVAISKLMVYI  668
            +  + ++RV R I +  EI  E     +  Y  N+ V  +T+ ++  KFN AI++LMV++
Sbjct  656  GSRKFLDRVYRLITTK-EITEENSGALDKVY--NETVKAVTEQVDQMKFNTAIAQLMVFV  712

Query  669  NFLNKKQKIPSKNYLTDFLIIFSVFAPHTAee--llekleqkplNFQIWPQFDRSKIFKN  726
            N  NK +K+ S +Y  +F+ +++ FAPH +EE          ++++  WP +D SK+  N
Sbjct  713  NAANKEDKLFS-DYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVEN  771

Query  727  TFHLPVSINGKNRGILELTDEKSQEEIIEIAKKDYKIRNYLQNKQIIKVIYIPRKILNFI  786
              ++ V I+GK ++ L ++ + S+EE+ E+A  + K++  +  K+IIKVI +P K++N++
Sbjct  772  DVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIV  831

Query  787  LK  788
            +K
Sbjct  832  IK  833

1105) Ththe16_0228 in NC_017272


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  544 bits (2054),  Expect = 9e-156, Method: Compositional matrix adjust.
 Identities = 383/881 (44%), Positives = 563/881 (64%), Gaps = 58/881 (6%)

Query  4    YNPHAIEAKWQRFWEEK-GFMKAKDLPGGRGKQYVLVMFPYPSG-DLHMGHLKNYTMGDV  61
            Y+  AIE+KWQ FW ++  F  + D  +++ K Y L MFPYPSG +LH+GH   YT  D+
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTD--ASKPKFYALDMFPYPSGAGLHVGHPEGYTATDI  61

Query  62   LARFRRMQGYEVLHPMGWDAFGLPAENAALKFGVHPKDWTYANIRQAKESLRLMGILYDW  121
            L+RF+R QG +VLHPMGWDAFGLPAE+ A+  G +P + T  NI + K  +  +G+ YDW
Sbjct  62   LSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDW  121

Query  122  DREVTTCEPEYYRWNQWIFLKMWEKGLAYRAKGLVNWCPKCQTVLANEQVVEGRCWRHED  181
            DREV T +P+YY+W QWIF K+ EKGLAY A   VNW     T +ANE+V+ +    + +
Sbjct  122  DREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGG  181

Query  182  TPVEKRELEQWYLRITAYAERLLKDLDGLNWPEKVKAMQRAWIGRSEGAEILFPVEGKEV  241
             PV ++ + QW L+ITAYAERLL DL+ ++WPE +K MQR WIG+S GA++ F V + + 
Sbjct  182  YPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDK  241

Query  242  KIPVFTTRPDTLFGATFLVLAPEHPLTLKLAAPERREEVLAYVEAAKRKTEIERQAEGRE  301
             + VFTTRPDTLFGAT+ VLAPEH+L   ++++++ E V  Y   A  K+++ R   ++E
Sbjct  242  DFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKE  301

Query  302  KTGVFLGAYALNPATGERIPIWTADYVLFGYGTGAIMAVPAHDQRDFEFARKFGLPIKKV  361
            KTGV  G+YA+NP  G  +P+W ADYVL +YGTGAIMAVPAHD+RD EFA++F L I  V
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  362  IerpgeplpeplerAYEEPGIMVNSGPFDGTPSEEGKRKVITWLEEKGLGKGRVTYRLRD  421
            +        +  E A+ E G+ +NS+ +DG     +  K++ WLE  G+G+  VTYRLRD
Sbjct  362  L-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  422  WLISRQRYWGTPIPMVHCEACGvvpvpeeelpvllpDLKDIEDIRPKGK--SPLEAHPEF  479
            WL+SRQRYWG PIP++H E     +VPE ELP++   L    DIRP G   SPL    + 
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLV---LPVTKDIRPSGTGESPLANVTDW  473

Query  480  YETTCPKCGGPAKRdtdtmdtffdSSWYYLRYTDPHN-DRLPFDPEKANAWMPVDQYIGG  538
             E T    G  ++R+T+TM    +SSWYYLRY DPHN ++L+ D E  + W+PVD Y+GG
Sbjct  474  LEVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLA-DEELLKQWLPVDIYVGG  531

Query  539  VEHAVLHLLYSRFFTKFLHDLGMVKVEEPFKGLFTQGMVLAWTDFGPVEVEGSVVRLPEP  598
             EHAVLHLLY+RF  K L DLG+V   EPF+ LF QGM+L+ T +      +S   L   
Sbjct  532  AEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILG-TSY-----RDSRGALVAT  585

Query  599  TRIRLEIPQSELTLEEVKKMGAELRPHEDGTLHLWKPAVMSKSKGNGVMVGPFVKEQGAD  658
             ++              K+ G+ ++ + +  L+   PA MSKS  N V  +  V + GAD
Sbjct  586  DKVE-------------KRDGSFFHVETGEELEQ-APAKMSKSLKNVVNPDDVVEQYGAD  631

Query  659  IARITILFAAPPENEMVWTEEGVQGAWRFLNRIYRRVAEDREALLATSGRFQAEELAGAD  718
              R+  +F +P +  + W+EEG++G+++FL+R+YR        L++T     +EE +GA 
Sbjct  632  TLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYR--------LITTKEI--TEENSGAL  681

Query  719  RELYRKLHATLKKVTEDLEALRFNTAIAALMELLNVLYEYRKDRPVTPVYRTVIRYYLQM  778
              +Y   + T+K VTE+++ ++FNTAIA LM ++N     + D+    ++    + ++Q+
Sbjct  682  DKVY---NETVKAVTEQVDQMKFNTAIAQLMVFVNA--ANKEDK----LFSDYAKGFVQL  732

Query  779  LFPFAPHLAEELWHWF--WPDSLFEAGWPELDEKALEKDVVEVAVQVNGRVRGTIRIPKD  836
            + PFAPHL+EELW+ +    +S+    WP  DE  L  + VE+ VQ++G+V++ + ++KD
Sbjct  733  IAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKD  792

Query  837  APLEVAKAEALKVRNVRAHLEGKEVVKEIYVPGKILNLVVR  877
             + E  +  AL   +V+A++ GK+++K I VP K++N+V++
Sbjct  793  LSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

1106) Tcr_0479 in NC_007520


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  544 bits (2054),  Expect = 9e-156, Method: Compositional matrix adjust.
 Identities = 361/874 (42%), Positives = 547/874 (63%), Gaps = 54/874 (6%)

Query  13   YQPQSIEAAIQHVWDEQQVFVAKEDDSKEKFYCLSMFPYPSGK-LHMGHVRNYTIGDVVS  71
            Y+  +IE+  Q  W +++ F +  D SK KFY L MFPYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  72   RFQRMQGKNVLQPMGWDAFGLPAENAAMDNQVAPAKWTYQNIDYMRNQLKRLGLGYDWTR  131
            RF+R QG NVL+PMGWDAFGLPAE+ AMD    PA  T +NI   + Q++ LG++YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  132  EVATCHPEYYRWEQWLFTRLMEKGLVYRKLSVVNWDPVDQTVLANEQVI-DGKGWRSGVP  190
            EV T +P+YY+W QW+FT+L EKGL Y     VNW     T +ANE+V+ DG + R+G P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  191  VERKEIAQWFLRITDYAEELLTDLDQLEGWPEQVKTMQKNWIGKSTGLEIEFPIASGLDE  250
            V RK + QW L+IT YAE LL DL++++ WPE +K MQ+NWIGKSTG ++ F +     +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKV----KD  238

Query  251  SNGSLKVYTTRPDTLMGVTYVAVAADHPWARKASVNNEPLERFIEECSHISTAEADME--  308
            ++  + V+TTRPDTL G TY  +A++H+     + ++++    + +  + ++  +D+   
Sbjct  239  TDKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEA--VADYKRQASLKSDLART  296

Query  309  --TMEKKGVDTGIRVKHPITGDEVPVWAANFVLMGYGTGAVMSVPAHDQRDYEFAKAYDL  366
              + EK GV TG    +P+ G E+PVW A++VL +YGTGA+M+VPAHD+RD EFAK ++L
Sbjct  297  DLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNL  356

Query  367  PIKAVIAPKAGEEADVSEAAFTEKGVLVNSGQFDGLKSKQALHEMAKVLGELGLGEKQTN  426
             I +V+     E ++V EAAFTE G+ +NS+ +DGL    A+  M   L   G+G+ +  
Sbjct  357  DIIPVL-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVT  411

Query  427  YRLRDWGISRQRYWGCPIPVIYCPACGALPVPEKDLPVRLP--EDVVPDGSG-SPLAKLD  483
            YRLRDW +SRQRYWG PIP+I      + +VPE +LP+ LP   D+ P G+G SPLA++ 
Sbjct  412  YRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVT  471

Query  484  SFKKCECPQCGGPANRETDTFDTFFESSWYHARYTSRHEDNAMLDKAAADHWLPVDQYIG  543
                    + G  + RET+T      SSWY  RY   H+ + + D     +WLPVD Y+G
Sbjct  472  DWLEV-TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVG  530

Query  544  GIEHAILHLLYARFFHKLMRDEGLVSSDEPFKNLLTQGMVLAGSWFTQDEKGKQTWYSPL  603
            G EHA+LHLLYARF HK++ D G+V++ EPF++L+ QGM+L+ S   +D +G     + +
Sbjct  531  GAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS--YRDSRG-----ALV  583

Query  604  DVDPVTDDKGAIVKGTLKSDGTEVQYGGIIKMSKSKNNGIDPQTLIDQYGADTLRLYIMF  663
              D V    G++        G E++  +  KMSKS +N ++P+ +++QYGADTLR+Y MF
Sbjct  584  ATDKVEKRDGSFFHV---ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMF  639

Query  664  ASPPEQTLEWSDSAVEGAHRFLNRVWRQVQTHVSTGVVAACTSNDDLTKEQKALRLKLHT  723
             +P + ++ WS+ ++EG+++FL+RV R + T              ++T E+ +   K+  
Sbjct  640  MGPLDASIAWSEEGLEGSRKFLDRVYRLITTK-------------EITEENSGALDKVYN  686

Query  724  TLQKVTDDMGRRMHFNTAIAATMELLNDISRFKDESDAGRSVMQEALEMLVLMLSPMTPH  783
               K   +   +M FNTAIA  M        F + ++    +  +    +V +++P +PH
Sbjct  687  ETVKAVTEQVDQMKFNTAIAQLMV-------FVNAANKEDKLFSDYAKGFVQLIAPFAPH  739

Query  784  ASQALWEALGHDGLVLN-VTWPTVDDAALVKDEIEIMVQVNGKLRGKIEVAAEADKDTIL  842
             ++ LW+AL   G  ++ V WP+ D++ LV +++EI+VQ++GK+++K+ VA +  ++ + 
Sbjct  740  LGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQ  799

Query  843  aaakaneqaaKFIDGKDIVKEIVVPGRLVNIVVK  876
              A ANE+    I GKDI+K I VP +LVNIV+K
Sbjct  800  EVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

1107) leuS in NC_021716


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  543 bits (2051),  Expect = 1e-155, Method: Compositional matrix adjust.
 Identities = 359/874 (42%), Positives = 559/874 (64%), Gaps = 56/874 (6%)

Query  6    YNPKDIEQRVQQYWEENQSFKANDDVEKEKFYCLSMFPYPSGR-LHMGHVRNYTIGDVIS  64
            Y+   IE + Q +W +N++FK+  D  K KFY L MFPYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  65   RFQRMQGKNVLQPMGWDAFGLPAENAAINNNTAPAKWTYSNIDYMKNQLRSLGFGYDWDR  124
            RF+R QG NVL+PMGWDAFGLPAE+ A++    PA  T  NI   K Q+ +LGF+YDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  125  EVTTCKSDYYRWEQWFFTRLYEKGLVYKKNSTVNWDPVDQTVLANEQVI-DGRGWRSGAL  183
            EV T  ++YY+W QW+FT+LYEKGL Y  +  VNW     T +ANE+V+ DG + R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  184  VEQKEIPQWFIKITDYAeellqdleqleeWPDQVRAMQANWIGRSEGVEITFDLASAVND  243
            V +K + QW +KIT YA E L +  +  +WP+ ++ MQ NWIG+S G ++TF +  + + 
Sbjct  184  VVRKPMRQWMLKITAYA-ERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDK-  241

Query  244  IADLTVYTTRPDTFYGVTYVAVAAQHPLAEFAAQSNPDLAAFIEECKNTKVAEAELA---  300
              D+TV+TTRPDT++G TY  +A++H+L +  A + +D A  + + K      ++LA   
Sbjct  242  --DFTVFTTRPDTLFGATYAVLAPEHALVD--AITTSDQAEAVADYKRQASLKSDLARTD  297

Query  301  -TMEKKGFATGFEVIHPLTGEKLPIWVANFVLMDYGSGAVMAVPGHDQRDWEFATKYDLP  359
             + EK G  TG   I+P+ G  +P+W+A++VL  YG+GA+MAVP+HD+RDWEFA +++L 
Sbjct  298  LAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLD  357

Query  360  ITQVIAPNAGDEDKCDLSASAYTEKGSLINSDKFNGLEFDAAFNGIADELEGKGCGKRKV  419
            I  V+     +E       +A+TE G  INSD ++GL+  +A+  + + LE+ G G+ +V
Sbjct  358  IIPVLEGGNVEE-------AAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENV  410

Query  420  NYRLRDWGVSRQRYWGAPIPMLNLENGESVPVPADQLPVVLP--EDVEMNGVT-SPIKAD  476
             YRLRDW  SRQRYWG PIP+++ E+G S +VP  +LP+VLP   D+  +G   SP+   
Sbjct  411  TYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANV  470

Query  477  PEWAKTTY-NGEAALRETDTFDTFMESSWYYARYASATNNDAMLDPTSANYWLPVDQYIG  535
             +W   T  +G  + RET+T      SSWYY RY  + N + + D    + WLPVD Y+G
Sbjct  471  TDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVG  530

Query  536  GIEHAILHLLYSRFFHKLLRDEGLVNSDEPFKRLLCQGMVLADSYYREDEAGKKTWFSPT  595
            G EHA+LHLLY+RF HK+L D G+V + EPF++L+ QGM+L+ S YR+  ++        
Sbjct  531  GAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS-YRDSRGAL-------  582

Query  596  EVSTEKDDKGRIVKAWLTADGEEVIHGGMTKMSKSKNNGIDPQEVIDLYGADTVRLFTMF  655
             V+T+K +K     + +  +  E ++ + +KMSKS +N ++P++V++ YGADT+R++ MF
Sbjct  583  -VATDKVEKRD--GSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMF  639

Query  656  AAPPEQTLEWVDSGVEGANRFLRRIWKLVTEHVEKGTPEAIDVKSLSKDQQ-ALRREVHK  714
             +P + ++ W + G+EG+ +FL R+ +L+T             K ++ ++  AL +  + 
Sbjct  640  MGPLDASIAWSEEGLEGSRKFLDRVYRLIT------------TKEITEENSGALDKVYNE  687

Query  715  TIEKVSDDLGRRQTFNTAVAAVMELLNHLQKAPQESAQDIAIMREACESILLLLNPITPH  774
            T+  V++++++ + FNTA+A +M ++N  +K  +       +  +   +++ L+ P++PH
Sbjct  688  TVKAVTEQVDQMK-FNTAIAQLMVFVNAANKEDK-------LFSDYAKGFVQLIAPFAPH  739

Query  775  IAHELWKVL-GHSEDIDSAPWPQADKAALVEDEKLIIVQVNGKVRAKMTiaadaskeaie  833
            +++ELW+ L + +E I   PWP  D + LVE++  I+VQ++GKV+AK+ +A D S+E ++
Sbjct  740  LGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQ  799

Query  834  asakEQPNVQQFIEGKTIRKVIVVPGKLVNIVAN  867
              A  + +VQ  I GK I KVI VP KLVNIV +
Sbjct  800  EVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

1108) leuS in NC_012912


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  543 bits (2051),  Expect = 1e-155, Method: Compositional matrix adjust.
 Identities = 358/866 (42%), Positives = 556/866 (65%), Gaps = 48/866 (5%)

Query  5    YRPEDIEAHVQLHWQEKQTFKVTEEPGKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIS  63
            Y    IE+  Q  W +++TFK   +++K K+Y L M+PYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYANIEYMKNQLKLLGFGYDWDR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T  NI   K Q++ LGF+YDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVATCKPDYYRWEQWFFTKLYEKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            EV T  P+YY+W QW+FTKLYEKGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADELLNDLDTLESWPEQVKTMQRNWIGRSEGVEITFRIADADDT  242
            V RK + QW +KITAYA+ LL+DL+ ++ WPE +K MQRNWIG+S G ++TF++ D+D  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGVTYVAVAAGHPLAQ--KAAENNPALQDFIVECR-NTKVAEADMATME  299
            +TV+TTRPDT+ G TY  +A+ H+L +   ++++  A+ D+  +   ++ +A +D+A  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGVATGLFAIHPLTGENVPVWAANFVLMEYGTGAVMAVPGHDQRDWEFAHKYNLPVKPV  359
            K GV TG +AI+P+ G ++PVW A++VL  YGTGA+MAVP+HD+RDWEFA ++NL + PV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  360  ILLADGSEPDLSAQAQTEKGCLFNSGEF-DGLNFDAAFNAIADKLVSQGVGQRKVNYRLR  418
            +  ++  E+ ++ ++      L  +++F DGL+  +A+  + + L ++GVG+ +V YRLR
Sbjct  362  LEGGNVEEAAFTEDG------LHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  419  DWGVSRQRYWGAPIPMATLEDGTVVPMPEDQLPVVLP--EDVVMDGIT-SPIKADPEWAK  475
            DW  SRQRYWG PIP+   EDGT  ++PE +LP+VLP   D+   G   SP+    +W  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  476  TT-INGQPALRETDTFDTFMESSWYYARYTCPQYDQGMLDPAAANYWLPVDQYIGGIEHA  534
             T  +G  + RET+T      SSWYY RY  P+  + + D    + WLPVD Y+GG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  535  ILHLMYFRFFHKLMRDAGLVNSNEPAKRLLCQGMVLADAFYHLGNNGERIWVSPSDVTLE  594
            +LHL+Y RF HK++ D G+V ++EP ++L+ QGM+L+ ++      + R     + V+ +
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSR----GALVATD  586

Query  595  RDDKGRITKAFDNEGRELVYAGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPAEM  654
            + +K R    F+ E  E +  + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P + 
Sbjct  587  KVEK-RDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  655  TLEWQESGVEGANRFLKRVWKQVYDHTGKGATQPLDTAALTEDQKALRRDLHKTIAKVTD  714
            ++ W E G+EG+ +FL RV + +   T K  T+        E+  AL +  + T+  VT+
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLI---TTKEITE--------ENSGALDKVYNETVKAVTE  694

Query  715  DIGRRQTFNTAIAAIMELMNKLAKAPQDAEQDRALTQETLLAVVRMLYPFTPHACFVLWN  774
            ++++ + FNTAIA +M ++N        A+++  L  +   + V+++ PF+PH    LW+
Sbjct  695  QVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  775  ELKGEGD-IDQAPWPVADEQAMVEDSRLVVVQVNGKVRGKITVAADATEQQVRERAAQEP  833
             L + G+ I   PWP  DE  +VE+   +VVQ++GKV++K+ VA D + ++++E A  + 
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  834  LVAKYLDGVTVRKVIFVPGKLLNLVV  859
             V   + G  + KVI VP KL+N+V+
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVI  832

1109) leuS in NC_017663


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  543 bits (2051),  Expect = 1e-155, Method: Compositional matrix adjust.
 Identities = 363/865 (42%), Positives = 557/865 (65%), Gaps = 46/865 (5%)

Query  52   YRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIA  110
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  111  RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSR  170
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  171  ELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  229
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  230  VERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKTMQRNWIGRSEGVEITFNVNDYDNT  289
            V RK + QW +KITAYA+ LL+DL+ +D WP+++K MQRNWIG+S G ++TF+V+D D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  290  LTVYTTRPDTFMGCTYLAVAAGHPLAQ--KAAENNPELAAFIDECR-NTKVAEAEMATME  346
            +TV+TTRPDT+ G TY  +A+ H+L +   ++++   +A +  +   ++ +A +++A  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  347  KKGVDTGFKAVHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPV  406
            K GV TG  A++P+ G E+PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L+I PV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  407  ILAADGSEPDLSQQALTEKGVLFNSGEFNGLDHEAAFNAIADKLTAMGVGERKVNYRLRD  466
            +        ++ + A+TE G+ +NS+ ++GLD  +A+  + + L A GVG+ +V YRLRD
Sbjct  362  L-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  467  WGVSRQRYWGAPIPMVTLEDGTVMPTPDDQLPVILP--EDVVMDGIT-SPIKADPEWAKT  523
            W  SRQRYWG PIP++  EDGT  + P+ +LP++LP   D+   G   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  524  T-VNGMPALRETDTFDTFMESSWYYARYTCPQYKEGMLDSEAANYWLPVDIYIGGIEHAI  582
            T  +G+ + RET+T      SSWYY RY  P+  E + D E  + WLPVDIY+GG EHA+
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  583  MHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVER  642
            +HLLY RF HK++ D G+V + EP ++L+ QGM+L+ +  Y +  G    + + D +  R
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS--YRDSRGA---LVATDKVEKR  591

Query  643  DEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMT  702
            D  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D +
Sbjct  592  D--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  703  LEWQESGVEGANRFLKRVWKLVYEHTAKGDVAALNVDALTENQKALRRDVHKTIAKVTDD  762
            + W E G+EG+ +FL RV +L+   T+K        +   EN  AL +  + T+  VT++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLI---TTK--------EITEENSGALDKVYNETVKAVTEQ  695

Query  763  IGRRQTFNTAIAAIMELMNKLAKAPTDGEQDRALMQEALLAVVRMLNPFTPHICFTLWQE  822
            +++ + FNTAIA +M ++N        ++++  L  +   + V+++ PF+PH+   LWQ 
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  823  LKGEGD-IDNAPWPVADEKAMVEDSTLVVVQVNGKVRAKITVPVDATEEQVRERAGQEHL  881
            L + G+ I   PWP  DE  +VE+   +VVQ++GKV+AK+ V+ D + E+++E A  ++ 
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  882  VAKYLDGVTVRKVIYVPGKLLNLVV  906
            V   + G  + KVI VP KL+N+V+
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVI  832

1110) Dd586_1143 in NC_013592


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  543 bits (2051),  Expect = 1e-155, Method: Compositional matrix adjust.
 Identities = 352/866 (41%), Positives = 554/866 (64%), Gaps = 48/866 (5%)

Query  5    YRPEDIEAHVQLHWQEKQTFKVTEEPGKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIS  63
            Y    IE+  Q  W +++TFK   +++K K+Y L M+PYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIEYMKNQLKLLGFGYDWDR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NI   K Q++ LGF+YDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EIATCKPDYYRWEQWFFTKLYEKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W QW+FTKLYEKGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADELLNDLDTLESWPEQVKTMQRNWIGRSEGVEITFRIADADDT  242
            V RK + QW +KITAYA+ LL+DL+ ++ WPE +K MQRNWIG+S G ++TF++ D+D  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGVTYVAVAAGHPL--ALKAAESNPVLQDFIAECR-NTKVAEADMATME  299
            +TV+TTRPDT+ G TY  +A+ H+L  A+ +++    + D+  +   ++ +A +D+A  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGVATGLFAIHPLTGEKVPVWAANFVLMEYGTGAVMAVPGHDQRDWEFAHKYNLPVKPV  359
            K GV TG +AI+P+ G  +PVW A++VL  YGTGA+MAVP+HD+RDWEFA ++NL + PV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  360  ILMADGSEPDLSTQAQTEKGCLFNSGEF-NGLDFDAAFNAIADKLVSQGVGQRKVNYRLR  418
            +  ++  E+ ++ ++      L  +++F +GLD  +A+  + + L ++GVG+ +V YRLR
Sbjct  362  LEGGNVEEAAFTEDG------LHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  419  DWGVSRQRYWGAPIPMVTLEDGTVIPTPEDQLPVILP--EDVVMDGIT-SPIKADPEWAK  475
            DW  SRQRYWG PIP++  EDGT  + PE +LP++LP   D+   G   SP+    +W  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  476  TT-VNGQPALRETDTFDTFMESSWYYARYTCPQYDQGMLDPAAANYWLPVDQYVGGIEHA  534
             T  +G  + RET+T      SSWYY RY  P+  + + D    + WLPVD YVGG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  535  IMHLMYFRFFHKLMRDAGLVNSNEPAKRLLCQGMVLADAFYHLGNNGERIWVSPVDVTLE  594
            ++HL+Y RF HK++ D G+V ++EP ++L+ QGM+L+ ++      + R       V+ +
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSR----GALVATD  586

Query  595  RDDKGRITKAFDSEGRELVYAGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPAEM  654
            + +K R    F+ E  E +  + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P + 
Sbjct  587  KVEK-RDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  655  TLEWQESGVEGANRFLKRVWKQVYDHTGKGASAPLDTAALTDDQKALRRDLHKTIAKVTD  714
            ++ W E G+EG+ +FL RV + +   T K  +         ++  AL +  + T+  VT+
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLI---TTKEITE--------ENSGALDKVYNETVKAVTE  694

Query  715  DIGRRQTFNTAIAAIMELMNKLAKAPQESEQDRALTQETLLAVVRMLYPFTPHVCFVLWN  774
            ++++ + FNTAIA +M ++N        ++++  L  +   + V+++ PF+PH+   LW+
Sbjct  695  QVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  775  ELKGEGD-IDQAPWPVADEQAMVEDSRLVVVQVNGKVRGKITVAADATEQQVRDRAAQEP  833
             L + G+ I   PWP  DE  +VE+   +VVQ++GKV++K+ VA D + +++++ A  + 
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  834  LVAKYLDGVTVRKVIFVPGKLLNLVV  859
             V   + G  + KVI VP KL+N+V+
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVI  832

1111) leuS in NC_017634


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  543 bits (2050),  Expect = 2e-155, Method: Compositional matrix adjust.
 Identities = 360/865 (42%), Positives = 556/865 (65%), Gaps = 46/865 (5%)

Query  52   YRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIA  110
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  111  RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSR  170
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  171  ELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  229
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  230  VERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKTMQRNWIGRSEGVEITFNVKDYDNT  289
            V RK + QW +KITAYA+ LL+DL+ +D WP+++K MQRNWIG+S G ++TF+VKD D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  290  LTVYTTRPDTFMGCTYLAVAAGHPLAQ--KAAENNPELAAFIDECR-NTKVAEAEMATME  346
            +TV+TTRPDT+ G TY  +A+ H+L +   ++++   +A +  +   ++ +A +++A  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  347  KKGVDTGFKAVHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPV  406
            K GV TG  A++P+ G E+PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L+I PV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  407  ILAADGSEPDLSQQALTEKGVLFNSGEFNGLDHEAAFNAIADKLTEMGVGERKVNYRLRD  466
            +        ++ + A+TE G+ +NS+ ++GLD  +A+  + + L   GVG+ +V YRLRD
Sbjct  362  L-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  467  WGVSRQRYWGAPIPMVTLEDGTVMPTPDDQLPVILP--EDVVMDGIT-SPIKADPEWAKT  523
            W  SRQRYWG PIP++  EDGT  + P+ +LP++LP   D+   G   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  524  T-VNGMPALRETDTFDTFMESSWYYARYTCPEYKEGMLDSKAANYWLPVDIYIGGIEHAI  582
            T  +G+ + RET+T      SSWYY RY  P+  E + D    + WLPVDIY+GG EHA+
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  583  MHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVER  642
            +HLLY RF HK++ D G+V + EP ++L+ QGM+L+ ++      + R  + + D +  R
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEKR  591

Query  643  DEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMT  702
            D  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D +
Sbjct  592  D--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  703  LEWQESGVEGANRFLKRVWKLVYEHTAKGDVAALNVDVLTEDQKALRRDVHKTIAKVTDD  762
            + W E G+EG+ +FL RV +L+   T+K        ++  E+  AL +  + T+  VT++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLI---TTK--------EITEENSGALDKVYNETVKAVTEQ  695

Query  763  IGRRQTFNTAIAAIMELMNKLAKAPTDGEQDRALMQEALLAVVRMLNPFTPHICFTLWQE  822
            +++ + FNTAIA +M ++N        ++++  L  +   + V+++ PF+PH+   LWQ 
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  823  LKGEGD-IDNAPWPVADEKAMVEDSTLVVVQVNGKVRAKITVPVDATEEQVRERAGQEHL  881
            L + G+ I   PWP  DE  +VE+   +VVQ++GKV+AK+ V+ D + E+++E A  ++ 
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  882  VAKYLDGVTVRKVIYVPGKLLNLVV  906
            V   + G  + KVI VP KL+N+V+
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVI  832

1112) leuS in NC_008228


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  543 bits (2051),  Expect = 2e-155, Method: Compositional matrix adjust.
 Identities = 362/878 (42%), Positives = 553/878 (63%), Gaps = 57/878 (6%)

Query  4    KIYEPQKIEQEVQALWETNQTFKATEQEDKEKFYCLSMFPYPSGR-LHMGHVRNYTIGDV  62
             +Y+   IE   QA+W  N+TFK+  +  K KFY L MFPYPSG  LH+GH   YT  D+
Sbjct  2    TFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDI  61

Query  63   VSRFQRMNGKNVLQPMGWDAFGLPAENAALNNNTAPAKWTYQNIDYMKNQLKSLGFGYDW  122
            +SRF+R +G NVL+PMGWDAFGLPAE+ A++    PA  T +NI   K Q+++LGF+YDW
Sbjct  62   LSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDW  121

Query  123  DREVATCKKDYYRWEQWFFTRLYEKGLVYKKNSTVNWDPVDHTVLANEQVI-DGRGWRSG  181
            DREV T   +YY+W QW+FT+LYEKGL Y  +  VNW     T +ANE+V+ DG + R+G
Sbjct  122  DREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGG  181

Query  182  ALVEQKEIPQWFIKITDYAeelltdleqledWPEQVRAMQKNWIGRSEGVDITFNLSENA  241
              V +K + QW +KIT YA E L +  +  DWPE ++ MQ+NWIG+S G ++TF++ +  
Sbjct  182  YPVVRKPMRQWMLKITAYA-ERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  242  ADISSFDVYTTRPDTLYGVTYvavaaqhplalhaaqTRPELAEFIESCKNTKVAEAELA-  300
             D   F V+TTRPDTL+G TY         AL  A T ++ AE +   K      ++LA 
Sbjct  241  KD---FTVFTTRPDTLFGATY--AVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLAR  295

Query  301  ---TMEKKGCDTGLFAIHPLTGEKVAVWVANFVLMGYGSGAVMSVPGHDQRDWEFAQKYG  357
               + EK G  TG +AI+P+ G  ++VW+A++VL +YG+GA+M+VP+HD+RDWEFA+++ 
Sbjct  296  TDLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFN  355

Query  358  LPIKQVVEPSADEPQECDLTTAAYTDKGVLVNSAEFNGLAFQEAFDAIAAKLEALGAGSK  417
            L I  V+E +       ++  AA+T+ G+ +NS  ++GL    A+  +   LEA G G+ 
Sbjct  356  LDIIPVLEGG-------NVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNE  408

Query  418  KVNYRLRDWGVSRQRYWGSPIPMLNLENGESVPVPSDQLPVELP--EDVQMNGV-ISPIK  474
            +V YRLRDW  SRQRYWG PIP+++ E+G S +VP  +LP+ LP   D++ +G   SP+ 
Sbjct  409  NVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLA  468

Query  475  ADPDWAK-TEYNGQPALRETDTFDTFMESSWYYARYCSAQNQDAMLDPTQANYWLPVDQY  533
               DW   T  +G  + RET+T      SSWYY RY  ++N + + D    + WLPVD Y
Sbjct  469  NVTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIY  528

Query  534  VGGIEHAILHLLYSRFFHKLLRDEGLVNSDEPYKRLLCQGMVLADSFFREDESGKKEWFS  593
            VGG EHA+LHLLY+RF HK+L D G+V + EP+++L+ QGM+L+ S +R+  +      +
Sbjct  529  VGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS-YRDSRG------A  581

Query  594  PADVDTVKDEKGRITQATLKADGKPVEHGGMTKMSKSKNNGIDPQHVIDLYGADTIRVFT  653
                D V    G + +      G  +E++  +KMSKS +N ++P++V++ YGADT+RV+ 
Sbjct  582  LVATDKVEKRDGSFFHV---ETGEELEQAP-AKMSKSLKNVVNPDDVVEQYGADTLRVYE  637

Query  654  MFAAPPEQTLEWVDSGVEGANRFIKRVWKLTQDHIDALDGDTAPAIDKTALTGDQKTLRR  713
            MF +P + ++ W + G+EG+ +F+ RV +L                 K     +  +L +
Sbjct  638  MFMGPLDASIAWSEEGLEGSRKFLDRVYRLI--------------TTKEITEENSGALDK  683

Query  714  AVHRTIAKVTDDVGRRQTFNTAVAAIMELLNSLQRAPQSTDQDKAVLREAIESVVLLLNP  773
              + T+  VT++V++ + FNTA+A +M ++N       +++++  ++ +   + V L+ P
Sbjct  684  VYNETVKAVTEQVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAP  735

Query  774  IAPHMCHILWHDLGHKND-IETAPWPAVDESALVEDEKLIIVQVNGKVRSKITVAADASQ  832
            +APH+ + LW+ L    + I   PWP+ DES LVE++  I+VQ++GKV++K+ VA D S+
Sbjct  736  FAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSR  795

Query  833  EEVQALGLAQENVQQFVDGKTIRKVIYIAGKLLNIVAN  870
            EE+Q ++LA+E+VQ  + GK I KVI ++ KL+NIV +
Sbjct  796  EELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

1113) Sde_3308 in NC_007912


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  543 bits (2048),  Expect = 2e-155, Method: Compositional matrix adjust.
 Identities = 356/861 (42%), Positives = 539/861 (63%), Gaps = 75/861 (8%)

Query  4    YYQPSEIEAQAQKYWEENKSFNVTEDPTKEKFYCLAMFPYPSGR-LHMGHVRNYTISDVI  62
            +Y+ + IE++ Q +W +N +F+   D++K KFY L MFPYPSG  LH+GH   YT +D++
Sbjct  3    FYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDIL  62

Query  63   SRFHRMQGKNVLHPMGWDAFGLPAENAAIKNNTAPAKWTYSNTDYMRKQLTELGFGFDWS  122
            SRF R QG NVLHPMGWDAFGLPAE+ A+     PA  T  N    ++Q+  LGF++DW 
Sbjct  63   SRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWD  122

Query  123  REVTTCKPDYYKWEQWFFTRLYEKGLAYKKVASVNWCPNDQTVLANEQVV-DGQCWRCDT  181
            REV T  P+YYKW QW+FT+LYEKGLAY    +VNW  +  T +ANE+V+ DG   R + 
Sbjct  123  REVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGY  182

Query  182  AVERKEIPQWFIRITDYAEELLADLDKLPNWPEQVKTMQRNWIGKSQGVEMRFDLANPIA  241
            +V RK + QW ++IT YAE LL DL+ + +WPE +K MQRNWIGKS G ++ F + +   
Sbjct  183  PVVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDT--  239

Query  242  GTTGFDVYTTRPDTLMGVTYVSLAAEHPIAKALAETNP--ALAAFIQECKVQS-VAEADM  298
               +F V+TTRPDTL G TY  LA+EH++  A++ ++   A+A + ++  ++S +A +D+
Sbjct  240  -DKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDL  298

Query  299  ANMEKKGIDTGIKAKHPITGDEVSVWVANYVLMDYGSGAVMAVPAHDQRDWEFAKKYDLE  358
            A+ EK G+ TG  A +P+ G E++VW+A+YVL  YG+GA+MAVPAHD+RDWEFAK+++L+
Sbjct  299  AK-EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLD  357

Query  359  IKQVIAPEDGSDIDLTKEAFVDKGVLVNSGEYDGLNFNAAFEAISQTLQAANKGKVTTNF  418
            I  V+   +G++++    AF + G+ +NS+  DGL+  +A+  + + L+A   G+    +
Sbjct  358  IIPVL---EGGNVE--EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTY  412

Query  419  RLRDWGVSRQRYWGSPIPIFNLPDGGVIPVPADRLPVLLP--EDVQMDGV-QSPIKADKE  475
            RLRDW  SRQRYWG PIPI++  DG   +VP   LP++LP   D++  G  +SP+    +
Sbjct  413  RLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTD  472

Query  476  WCKAEL-NGQAVEHETDTFDTFMESSWYYARYTSP-NADSMLDPDKANYWLPVDQYVGGI  533
            W      +G    +ET+T      SSWYY RY  P N++ + D +  + WLPVD YVGG 
Sbjct  473  WLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGA  532

Query  534  EHAILHLLYARFFHKLMRDEGLVECDEPFERLLCQGMVL-------------------KD  574
            EHA+LHLLYARF HK++ D G+V   EPF++L+ QGM+L                   +D
Sbjct  533  EHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRD  592

Query  575  GT---------------KMSKSKGNTVDPEDLIKTYGADTVRLFSMFAAPPEQSLEWTDS  619
            G+               KMSKS  N V+P+D++  YGADT+R++ MF +P + S+ W++ 
Sbjct  593  GSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEE  652

Query  620  GVEGAFRFLKKLWKAVASHLEAGSAGEIDANSLDEQQKALRRKTHETISKVSDDYGRRQT  679
            G+EG+ +FL ++ + +++            +  +E+  AL +  +ET+  V+++ ++ + 
Sbjct  653  GLEGSRKFLDRVYRLITTK-----------EITEENSGALDKVYNETVKAVTEQVDQMK-  700

Query  680  FNTAIAAVMELLNEITRSADRSTPNGlaverealeaatlllaPIVPHACHALWQAFGNEV  739
            FNTAIA +M ++N   +     +  +         +   L+AP+ PH  + LWQA+    
Sbjct  701  FNTAIAQLMVFVNAANKEDKLFSDYA--------KGFVQLIAPFAPHLGEELWQALTASG  752

Query  740  AVLD-APWPTVDEAALVKDTITIVAQVNGKVRAKLDAPANADKDALEKIALADESVLKHI  798
              +   PWP+ DE+ LV + + IV Q++GKV+AKL  + +  ++ L+ +ALA+E V  +I
Sbjct  753  ESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEI  812

Query  799  DGKMIRKVIVVPGKLVNIVAN  819
             GK I KVI VP KLVNIV +
Sbjct  813  AGKDIIKVIAVPNKLVNIVIK  833

1114) leuS in NC_017328


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  543 bits (2051),  Expect = 2e-155, Method: Compositional matrix adjust.
 Identities = 361/865 (42%), Positives = 558/865 (65%), Gaps = 46/865 (5%)

Query  36   YRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIA  94
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  95   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSR  154
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  155  ELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  213
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  214  VERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKTMQRNWIGRSEGVEITFNVNDYDNT  273
            V RK + QW +KITAYA+ LL+DL+ +D WP+++K MQRNWIG+S G ++TF+V+D D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  274  LTVYTTRPDTFMGCTYLAVAAGHPLAQ--KAAENNPELAAFIDECR-NTKVAEAEMATME  330
            +TV+TTRPDT+ G TY  +A+ H+L +   ++++   +A +  +   ++ +A +++A  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  331  KKGVDTGFKAVHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPV  390
            K GV TG  A++P+ G E+PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L+I PV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  391  ILAADGSEPDLSQQALTEKGVLFNSGEFNGLDHEAAFNAIADKLTAMGVGERKVNYRLRD  450
            +        ++ + A+TE G+ +NS+ ++GLD  +A+  + + L A GVG+ +V YRLRD
Sbjct  362  L-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  451  WGVSRQRYWGAPIPMVTLEDGTVMPTPDDQLPVILP--EDVVMDGIT-SPIKADPEWAKT  507
            W  SRQRYWG PIP++  EDGT  + P+ +LP++LP   D+   G   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  508  T-VNGMPALRETDTFDTFMESSWYYARYTCPEYKEGMLDSEAANYWLPVDIYIGGIEHAI  566
            T  +G+ + RET+T      SSWYY RY  P+  E + D E  + WLPVDIY+GG EHA+
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  567  MHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVER  626
            +HLLY RF HK++ D G+V + EP ++L+ QGM+L+ ++      + R  + + D +  R
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEKR  591

Query  627  DEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMT  686
            D  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D +
Sbjct  592  D--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  687  LEWQESGVEGANRFLKRVWKLVYEHTAKGDVAALNVDALTEDQKALRRDVHKTIAKVTDD  746
            + W E G+EG+ +FL RV +L+   T+K        +   E+  AL +  + T+  VT++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLI---TTK--------EITEENSGALDKVYNETVKAVTEQ  695

Query  747  IGRRQTFNTAIAAIMELMNKLAKAPTDGEQDRALMQEALQAVVRMLNPFTPHICFTLWQE  806
            +++ + FNTAIA +M ++N        ++++  L  +  ++ V+++ PF+PH+   LWQ 
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  807  LKGEGD-IDNAPWPVADEKAMVEDSTLVVVQVNGKVRAKITVPVDATEEQVRERAGQEHL  865
            L + G+ I   PWP  DE  +VE+   +VVQ++GKV+AK+ V+ D + E+++E A  ++ 
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  866  VAKYLDGVTVRKVIYVPGKLLNLVV  890
            V   + G  + KVI VP KL+N+V+
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVI  832

1115) leuS in NC_014532


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  543 bits (2049),  Expect = 2e-155, Method: Compositional matrix adjust.
 Identities = 353/871 (41%), Positives = 551/871 (64%), Gaps = 58/871 (6%)

Query  5    YKPFDIERDAQRFWDENQCFKAIEDTDREKFYCLSMFPYPSGK-LHMGHVRNYTIGDVVS  63
            Y    IE   Q FW +N+ FK+  D+ + KFY L MFPYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMQGKNVMQPMGWDAFGMPAENAAIQNQVPPARWTQQNIETMRAQLKSLGFAYDWSR  123
            R++R QG NV++PMGWDAFG+PAE+ A++    PA  T +NI   + Q+++LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EFATCDSDYYRWEQWFFTKLVEKGLVYKKMSMVNWDPVDQTVLANEQVI-EGRGWRSGAL  182
            E  T D++YY+W QW+FTKL EKGL Y     VNW     T +ANE+V+ +G + R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPLWFLKITDYAEELLADLDRIDWPEQVKTMQRNWIGKSRGVELTFDTHAADGSP  242
            V RK +  W LKIT YAE LL DL+ +DWPE +K MQRNWIGKS G ++TF    +D   
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKD-  242

Query  243  LEPLSVYTTRPDTLMGVTYLAVAADHPLAKSAARNDAALADFLEECARGGTSEAELA---  299
               ++V+TTRPDTL G TY  +A++H+L  + + +D   A+ + +  R ++  ++LA   
Sbjct  243  ---FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQ--AEAVADYKRQASLKSDLARTD  297

Query  300  -TKEKKGMPTGHSAIHPLSGRELPVYVANFVLMEFGTGAVMAVPAHDQRDWEFATKYGIP  358
             +KEK G+ TG  AI+P++G+E+PV +A++VL  +GTGA+MAVPAHD+RDWEFA ++ + 
Sbjct  298  LAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLD  357

Query  359  IEPVIADANGDTPDLSAGAHTEYGTLINSGEFDGLGFEAAFDAIAARLAEQGRGEVKTNY  418
            I PV+ ++N + + ++ +     G  INS+ +DGL+  +A+  +  +L  +G G+ +  Y
Sbjct  358  IIPVLEGGNVEEAAFTED-----GLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTY  412

Query  419  RLRDWGVARQRYWGAPIPVKYGPEGQTVPLSDDELPVSLPLEVTVDASG---SPLKKMPE  475
            RLRDW  +RQRYWG PIP+    +G + ++++ ELP+ LP+   + +SG   SPL ++ +
Sbjct  413  RLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTD  472

Query  476  FSDLG-----DGWTRETDTFDTFMESSWYFARFCCADNHTAMLDDR-ADYWLPVDLYIGG  529
              ++       G  RET+T      SSWY+ R+  ++N   + D+     WLPVD+Y+GG
Sbjct  473  WLEVTREDGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGG  531

Query  530  IEHAILHLLYARFFTKLMRDFGLVKADEPFQRLLTQGMVIAETYYRPTANGGKQWFNPAD  589
             EHA+LHLLYARF  K++ D+G+V + EPFQ+L+ QGM+++ +Y    + G+        
Sbjct  532  AEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY--RDSRGAL-------  582

Query  590  VEVSRDDKGRPVSATLVADGQPVEMGGIEKMSKSKNNGVDPQAMIDRFGADTVRLFMMFA  649
            V   + +K R  S   V  G+ +E +   KMSKS +N V+P+ +++++GADT+R++ MF 
Sbjct  583  VATDKVEK-RDGSFFHVETGEELEQAP-AKMSKSLKNVVNPDDVVEQYGADTLRVYEMFM  640

Query  650  APPEQSLEWSDSGVEGAHRFLKRLWRLVAEHLEAGTPATLDTESLDDAQRELRRKTHETI  709
            +P + S+ WS+ G+EG+++FL R+ RL++             E  ++    L +  +ET+
Sbjct  641  GPLDASIAWSEEGLEGSRKFLDRVYRLIT-----------TKEITEENSGALDKVYNETV  689

Query  710  QKASDDIGRRTTFNTAIAAVMELTNALGKFDDTSPLGLAVAREAVEACVLLLAPITPHVC  769
            +  ++++++   FNTAIA +M + NA  K D        +  +   + V L+AP++PH+ 
Sbjct  690  KAVTEQVDQM-KFNTAIAQLMVFVNAANKEDK-------LFSDYAKGFVQLIAPFAPHLG  741

Query  770  HTLWAELGHDEPAID-ARWPALDESALARDTIELVAQVNGKLRARLEVPADANKAAIEAQ  828
            + LW  L     +I    WP+ DES L  + +E+V Q++GK++A+L V+ D ++  ++  
Sbjct  742  EELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEV  801

Query  829  AMATENVQRHIEGKTIRKVIVVPGKLVNIVV  859
            A+A E+VQ +I GK I KVI VP KLVNIV+
Sbjct  802  ALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

1116) leuS in NC_004741


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  543 bits (2048),  Expect = 3e-155, Method: Compositional matrix adjust.
 Identities = 361/865 (42%), Positives = 558/865 (65%), Gaps = 46/865 (5%)

Query  5    YRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIA  63
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKTMQRNWIGRSEGVEITFNVNDYDNT  242
            V RK + QW +KITAYA+ LL+DL+ +D WP+++K MQRNWIG+S G ++TF+V+D D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGCTYLAVAAGHPLAQ--KAAENNPELAAFIDECR-NTKVAEAEMATME  299
            +TV+TTRPDT+ G TY  +A+ H+L +   ++++   +A +  +   ++ +A +++A  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGVDTGFKAVHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPV  359
            K GV TG  A++P+ G E+PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L+I PV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  360  ILAADGSEPDLSQQALTEKGVLFNSGEFNGLDHEAAFNAIADKLTAMGVGERKVNYRLRD  419
            +        ++ + A+TE G+ +NS+ ++GLD  +A+  + + L A GVG+ +V YRLRD
Sbjct  362  L-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMVTLEDGTVMPTPDDQLPVILP--EDVVMDGIT-SPIKADPEWAKT  476
            W  SRQRYWG PIP++  EDGT  + P+ +LP++LP   D+   G   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  T-VNGMPALRETDTFDTFMESSWYYARYTCPEYKEGMLDSEAANYWLPVDIYIGGIEHAI  535
            T  +G+ + RET+T      SSWYY RY  P+  E + D E  + WLPVDIY+GG EHA+
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVER  595
            +HLLY RF HK++ D G+V + EP ++L+ QGM+L+ ++      + R  + + D +  R
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEKR  591

Query  596  DEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMT  655
            D  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D +
Sbjct  592  D--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  656  LEWQESGVEGANRFLKRVWKLVYEHTAKGDVAALNVDALTEDQKALRRDVHKTIAKVTDD  715
            + W E G+EG+ +FL RV +L+   T+K        +   E+  AL +  + T+  VT++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLI---TTK--------EITEENSGALDKVYNETVKAVTEQ  695

Query  716  IGRRQTFNTAIAAIMELMNKLAKAPTDGEQDRALMQEALQAVVRMLNPFTPHICFTLWQE  775
            +++ + FNTAIA +M ++N        ++++  L  +  ++ V+++ PF+PH+   LWQ 
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  776  LKGEGD-IDNAPWPVADEKAMVEDSTLVVVQVNGKVRAKITVPVDATEEQVRERAGQEHL  834
            L + G+ I   PWP  DE  +VE+   +VVQ++GKV+AK+ V+ D + E+++E A  ++ 
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  835  VAKYLDGVTVRKVIYVPGKLLNLVV  859
            V   + G  + KVI VP KL+N+V+
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVI  832

1117) leuS in NC_004337


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  543 bits (2048),  Expect = 3e-155, Method: Compositional matrix adjust.
 Identities = 361/865 (42%), Positives = 558/865 (65%), Gaps = 46/865 (5%)

Query  5    YRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIA  63
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKTMQRNWIGRSEGVEITFNVNDYDNT  242
            V RK + QW +KITAYA+ LL+DL+ +D WP+++K MQRNWIG+S G ++TF+V+D D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGCTYLAVAAGHPLAQ--KAAENNPELAAFIDECR-NTKVAEAEMATME  299
            +TV+TTRPDT+ G TY  +A+ H+L +   ++++   +A +  +   ++ +A +++A  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGVDTGFKAVHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPV  359
            K GV TG  A++P+ G E+PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L+I PV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  360  ILAADGSEPDLSQQALTEKGVLFNSGEFNGLDHEAAFNAIADKLTAMGVGERKVNYRLRD  419
            +        ++ + A+TE G+ +NS+ ++GLD  +A+  + + L A GVG+ +V YRLRD
Sbjct  362  L-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMVTLEDGTVMPTPDDQLPVILP--EDVVMDGIT-SPIKADPEWAKT  476
            W  SRQRYWG PIP++  EDGT  + P+ +LP++LP   D+   G   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  T-VNGMPALRETDTFDTFMESSWYYARYTCPEYKEGMLDSEAANYWLPVDIYIGGIEHAI  535
            T  +G+ + RET+T      SSWYY RY  P+  E + D E  + WLPVDIY+GG EHA+
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVER  595
            +HLLY RF HK++ D G+V + EP ++L+ QGM+L+ ++      + R  + + D +  R
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEKR  591

Query  596  DEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMT  655
            D  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D +
Sbjct  592  D--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  656  LEWQESGVEGANRFLKRVWKLVYEHTAKGDVAALNVDALTEDQKALRRDVHKTIAKVTDD  715
            + W E G+EG+ +FL RV +L+   T+K        +   E+  AL +  + T+  VT++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLI---TTK--------EITEENSGALDKVYNETVKAVTEQ  695

Query  716  IGRRQTFNTAIAAIMELMNKLAKAPTDGEQDRALMQEALQAVVRMLNPFTPHICFTLWQE  775
            +++ + FNTAIA +M ++N        ++++  L  +  ++ V+++ PF+PH+   LWQ 
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  776  LKGEGD-IDNAPWPVADEKAMVEDSTLVVVQVNGKVRAKITVPVDATEEQVRERAGQEHL  834
            L + G+ I   PWP  DE  +VE+   +VVQ++GKV+AK+ V+ D + E+++E A  ++ 
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  835  VAKYLDGVTVRKVIYVPGKLLNLVV  859
            V   + G  + KVI VP KL+N+V+
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVI  832

1118) Tcur_1582 in NC_013510


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  542 bits (2047),  Expect = 3e-155, Method: Compositional matrix adjust.
 Identities = 360/851 (43%), Positives = 540/851 (64%), Gaps = 60/851 (7%)

Query  23   YDPRAVQEKWQARWAEMDPYRAEESDDDPRERRYALDMFPYPSG-DLHMGHAEAFAIGDV  81
            YD  A++ KWQA WA+ + +++  + D ++ + YALDMFPYPSG +LH+GH+E+++  D+
Sbjct  4    YDHTAIEPKWQAFWADNHTFKT--GTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDI  61

Query  82   VARYWFQRGYNVLHPIGWDSFGLPAENAAIKRNEHPAKWTYANIETQAASFRRYAPSFDW  141
            ++R+   +G NVLHP+GWD+FGLPAE+ A+   ++PA  T  NI      +   + S+DW
Sbjct  62   LSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDW  121

Query  142  SRRLHTSDPEYYKWTQWLFLRFYERGLAYRKGGQVNWCPNDQTVLANEQVV-GGHCERCG  200
             R ++T+DP+YYKWTQW+F ++YE+GLAY     VNW  +  T +ANE+V+ +G  ER G
Sbjct  122  DREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGG  181

Query  201  ALVERRTLTQWYFRITEYADRLLEDMKQLEGKWPERVLVMQRNWIGRSTGADVDFVIEGR  260
              V R+ + QW ++IT YA+RLLED+ +++  WPE +  MQRNWIG+STGA+V F + + 
Sbjct  182  YPVVRKPMRQWMLKITAYAERLLEDLEEVD--WPESIKDMQRNWIGKSTGANVTFKVKDT  239

Query  261  KEPVTVFTTRPDTLYGATFFVVAADAPLADEICAPEQRAEFEAYREQVSRESEIDRLSTE  320
                TVFTTRPDTL+GAT+ V+A++ +L D I +++Q      Y+ Q S  S++ R    
Sbjct  240  DKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA  299

Query  321  REKTGVFLGRYAINPVNGERIPIWASDYVLAEYGHGAIMAVPAHDQRDLDFARKFGLPVR  380
            +EKTGV  G YAINPVNG  +P+W +DYVLA YG GAIMAVPAHD+RD +FA++F L + 
Sbjct  300  KEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDII  359

Query  381  VVVDTGEEDPAVTGVATPGDGRLINSGPLNGLNKAEAIKKIIQILEEKGLGKAAVNYRLR  440
             V++ G+    V   A   DG  INS+ L+GL+KA AI K+++ LE  G+G+  V YRLR
Sbjct  360  PVLEGGN----VEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  441  DWLVSRQRFWGCPIPIIHCPSCGEVPVPDEDLPVTLPDNLRGADLAPKGTSPLAAATDWV  500
            DWL SRQR+WG PIPIIH       +VP+ +LP+ LP   ++   +  G SPLA  TDW+
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVT-KDIRPSGTGESPLANVTDWL  474

Query  501  NVSCPKCGGAAKRDSDTMDTFVDSSWYYFRYCSPDYTEGPFDVEQVRKWMPVDQYTGGVE  560
            +V+    G  ++R+++TM    +SSWYY+RY  P+ TE   D E +++W+PVD Y GG E
Sbjct  475  EVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAE  533

Query  561  HAILHLLYSRFFTKVLHDMGMVDFTEPFTRLLNQGQVI----------------------  598
            HA+LHLLY+RF  KVL D+G+V   EPF +L+NQG ++                      
Sbjct  534  HAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDG  593

Query  599  ----------LNGKA--MSKSTGNLVDLGEQIAEHGVDVVRLAMLFSGPPEDDIDWADVS  646
                      L+  +  MSKS  N+V+ ++ + + G D +R+  +F GP +  I W++ +
Sbjct  594  SFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEG  653

Query  647  PGAMTKFLGRVHRIAAETAAPVGADPATGDVALRRVTHRTIDEVTTLVEAYRFNVAIARI  706
              +  KFL+RV R+ +       ++  +G  AL +V + T+  VT  V+  +FN AIA++
Sbjct  654  LEGSRKFLDRVYRLITTKEI---TEENSG--ALDKVYNETVKAVTEQVDQMKFNTAIAQL  708

Query  707  MELVSATRRAIDSGPGAADPAVREAAETIAVLLSLFAPYTAEEAWE-LLGRQAPVAKAGW  765
            M +V+A+ +         D    + A  +  L++ FAP  +EE W+ L +   +++   W
Sbjct  709  MVFVNAANK--------EDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPW  760

Query  766  PSADPALLVEEEVTCVVQVAGKVRDRLQVSPSIseeelerlalaseKVTAALGGAGIRKV  825
            PS D + LVE++V  VVQ+ GKV+ +L V+  +S EEL+ +ALA+EKV A ++G +I KV
Sbjct  761  PSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKV  820

Query  826  IVRAPKIVNIV  836
            I  + K+VNIV
Sbjct  821  IAVPNKLVNIV  831

1119) leuS in NC_019393


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  542 bits (2047),  Expect = 3e-155, Method: Compositional matrix adjust.
 Identities = 359/874 (42%), Positives = 558/874 (64%), Gaps = 56/874 (6%)

Query  6    YNPKDIEQRVQQYWEENQSFKANDDVEKEKFYCLSMFPYPSGR-LHMGHVRNYTIGDVIS  64
            Y+   IE + Q +W +N++FK+  D  K KFY L MFPYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  65   RFQRMQGKNVLQPMGWDAFGLPAENAAINNNTAPAKWTYSNIDYMKNQLRSLGFGYDWDR  124
            RF+R QG NVL+PMGWDAFGLPAE+ A++    PA  T  NI   K Q+ +LGF+YDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  125  EVTTCKADYYRWEQWFFTRLYEKGLVYKKNSTVNWDPVDQTVLANEQVI-DGRGWRSGAL  183
            EV T  ++YY+W QW+FT+LYEKGL Y  +  VNW     T +ANE+V+ DG + R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  184  VEQKEIPQWFIKITDYAeellqdleqleeWPDQVRAMQANWIGRSEGVEITFDLASAVND  243
            V +K + QW +KIT YA E L +  +  +WP+ ++ MQ NWIG+S G ++TF +  + + 
Sbjct  184  VVRKPMRQWMLKITAYA-ERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDK-  241

Query  244  IADLTVYTTRPDTFYGVTYVAVAAQHPLAEFAAQSNPDLAAFIEECKNTKVAEAELA---  300
              D+TV+TTRPDT++G TY  +A++H+L +  A + +D A  + + K      ++LA   
Sbjct  242  --DFTVFTTRPDTLFGATYAVLAPEHALVD--AITTSDQAEAVADYKRQASLKSDLARTD  297

Query  301  -TMEKKGFATGFEVIHPLTGEKLPIWVANFVLMDYGSGAVMAVPGHDQRDWEFATKYDLP  359
             + EK G  TG   I+P+ G  +P+W+A++VL  YG+GA+MAVP+HD+RDWEFA +++L 
Sbjct  298  LAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLD  357

Query  360  ITQVIAPNAGDEDKCDLSASAYTEKGSLINSDKFNGLAFDAAFNGIADELEGKGCGKRKV  419
            I  V+     +E       +A+TE G  INSD ++GL   +A+  + + LE+ G G+ +V
Sbjct  358  IIPVLEGGNVEE-------AAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENV  410

Query  420  NYRLRDWGVSRQRYWGAPIPMLNLENGESVPVPADQLPVVLP--EDVEMNGVT-SPIKAD  476
             YRLRDW  SRQRYWG PIP+++ E+G S +VP  +LP+VLP   D+  +G   SP+   
Sbjct  411  TYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANV  470

Query  477  PEWAKTTY-NGEAALRETDTFDTFMESSWYYARYASATNNDAMLDPTSANYWLPVDQYIG  535
             +W   T  +G  + RET+T      SSWYY RY  + N + + D    + WLPVD Y+G
Sbjct  471  TDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVG  530

Query  536  GIEHAILHLLYSRFFHKLLRDEGLVNSDEPFKRLLCQGMVLADSYYREDEAGKKTWFSPT  595
            G EHA+LHLLY+RF HK+L D G+V + EPF++L+ QGM+L+ S YR+  ++        
Sbjct  531  GAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS-YRDSRGAL-------  582

Query  596  EVSTEKDDKGRIVKAWLTADGEEVIHGGMTKMSKSKNNGIDPQEVIDLYGADTVRLFTMF  655
             V+T+K +K     + +  +  E ++ + +KMSKS +N ++P++V++ YGADT+R++ MF
Sbjct  583  -VATDKVEKRD--GSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMF  639

Query  656  AAPPEQTLEWVDSGVEGANRFLRRIWKLVTEHVEKGTPEAIDVKSLSKDQQ-ALRREVHK  714
             +P + ++ W + G+EG+ +FL R+ +L+T             K ++ ++  AL +  + 
Sbjct  640  MGPLDASIAWSEEGLEGSRKFLDRVYRLIT------------TKEITEENSGALDKVYNE  687

Query  715  TIEKVSDDLGRRQTFNTAVAAVMELLNHLQKAPQESAQDIAIMREACESILLLLNPITPH  774
            T+  V++++++ + FNTA+A +M ++N  +K  +       +  +   +++ L+ P++PH
Sbjct  688  TVKAVTEQVDQMK-FNTAIAQLMVFVNAANKEDK-------LFSDYAKGFVQLIAPFAPH  739

Query  775  IAHELWKVL-GHSEDIDSAPWPQADKAALVEDEKLIIVQVNGKVRAKMTiaadaskeaie  833
            +++ELW+ L + +E I   PWP  D + LVE++  I+VQ++GKV+AK+ +A D S+E ++
Sbjct  740  LGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQ  799

Query  834  asakEQPNVQQFIEGKTIRKVIVVPGKLVNIVAN  867
              A  + +VQ  I GK I KVI VP KLVNIV +
Sbjct  800  EVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

1120) leuS in NC_021710


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  542 bits (2047),  Expect = 3e-155, Method: Compositional matrix adjust.
 Identities = 360/874 (42%), Positives = 558/874 (64%), Gaps = 56/874 (6%)

Query  6    YNPKDIEQRVQQYWEENQSFKANDDVEKEKFYCLSMFPYPSGR-LHMGHVRNYTIGDVIS  64
            Y+   IE + Q +W +N++FK+  D  K KFY L MFPYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  65   RFQRMQGKNVLQPMGWDAFGLPAENAAINNNTAPAKWTYSNIDYMKNQLRSLGFGYDWDR  124
            RF+R QG NVL+PMGWDAFGLPAE+ A++    PA  T  NI   K Q+ +LGF+YDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  125  EVTTCKSDYYRWEQWFFTRLYEKGLVYKKNSTVNWDPVDQTVLANEQVI-DGRGWRSGAL  183
            EV T  ++YY+W QW+FT+LYEKGL Y  +  VNW     T +ANE+V+ DG + R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  184  VEQKEIPQWFIKITDYAeellqdleqleeWPDQVRAMQANWIGRSEGVEITFDLASAVND  243
            V +K + QW +KIT YA E L +  +  +WP+ ++ MQ NWIG+S G ++TF +  + + 
Sbjct  184  VVRKPMRQWMLKITAYA-ERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDK-  241

Query  244  IADLTVYTTRPDTFYGVTYVAVAAQHPLAEFAAQSNPDLAAFIEECKNTKVAEAELA---  300
              D+TV+TTRPDT++G TY  +A++H+L +  A + +D A  + + K      ++LA   
Sbjct  242  --DFTVFTTRPDTLFGATYAVLAPEHALVD--AITTSDQAEAVADYKRQASLKSDLARTD  297

Query  301  -TMEKKGFATGFEVIHPLTGEKLPIWVANFVLMDYGSGAVMAVPGHDQRDWEFATKYDLP  359
             + EK G  TG   I+P+ G  +P+W+A++VL  YG+GA+MAVP+HD+RDWEFA +++L 
Sbjct  298  LAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLD  357

Query  360  ITQVIAPNAGDEDKCDLSASAYTEKGSLINSDKFNGLAFDAAFNGIADELEGKGCGKRKV  419
            I  V+     +E       +A+TE G  INSD ++GL   +A+  + + LE+ G G+ +V
Sbjct  358  IIPVLEGGNVEE-------AAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENV  410

Query  420  NYRLRDWGVSRQRYWGAPIPMLNLENGESVPVPADQLPVVLP--EDVEMNGVT-SPIKAD  476
             YRLRDW  SRQRYWG PIP+++ E+G S +VP  +LP+VLP   D+  +G   SP+   
Sbjct  411  TYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANV  470

Query  477  PEWAKTTY-NGEAALRETDTFDTFMESSWYYARYASATNNDAMLDPTSANYWLPVDQYIG  535
             +W   T  +G  + RET+T      SSWYY RY  + N + + D    + WLPVD Y+G
Sbjct  471  TDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVG  530

Query  536  GIEHAILHLLYSRFFHKLLRDEGLVNSDEPFKRLLCQGMVLADSYYREDEAGKKTWFSPT  595
            G EHA+LHLLY+RF HK+L D G+V + EPF++L+ QGM+L+ S YR+  ++        
Sbjct  531  GAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS-YRDSRGAL-------  582

Query  596  EVSTEKDEKGRIVKAWLTADGEEVIHGGMTKMSKSKNNGIDPQEVIDLYGADTVRLFTMF  655
             V+T+K EK     + +  +  E ++ + +KMSKS +N ++P++V++ YGADT+R++ MF
Sbjct  583  -VATDKVEKRD--GSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMF  639

Query  656  AAPPEQTLEWVDSGVEGANRFLRRIWKLVTEHVEKGTPEAIDVKSLSKDQQ-ALRREVHK  714
             +P + ++ W + G+EG+ +FL R+ +L+T             K ++ ++  AL +  + 
Sbjct  640  MGPLDASIAWSEEGLEGSRKFLDRVYRLIT------------TKEITEENSGALDKVYNE  687

Query  715  TIEKVSDDLGRRQTFNTAVAAVMELLNHLQKAPQESAQDIAIMREACESILLLLNPITPH  774
            T+  V++++++ + FNTA+A +M ++N  +K  +       +  +   +++ L+ P++PH
Sbjct  688  TVKAVTEQVDQMK-FNTAIAQLMVFVNAANKEDK-------LFSDYAKGFVQLIAPFAPH  739

Query  775  IAHELWKVL-GHSEDIDSAPWPQADKAALVEDEKLIIVQVNGKVRAKMTiaadaskeaie  833
            +++ELW+ L + +E I   PWP  D + LVE++  I+VQ++GKV+AK+ +A D S+E ++
Sbjct  740  LGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQ  799

Query  834  asakEQPNVQQFIEGKTIRKVIVVPGKLVNIVAN  867
              A  + +VQ  I GK I KVI VP KLVNIV +
Sbjct  800  EVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

1121) leuS in NC_021717


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  542 bits (2047),  Expect = 3e-155, Method: Compositional matrix adjust.
 Identities = 360/874 (42%), Positives = 558/874 (64%), Gaps = 56/874 (6%)

Query  6    YNPKDIEQRVQQYWEENQSFKANDDVEKEKFYCLSMFPYPSGR-LHMGHVRNYTIGDVIS  64
            Y+   IE + Q +W +N++FK+  D  K KFY L MFPYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  65   RFQRMQGKNVLQPMGWDAFGLPAENAAINNNTAPAKWTYSNIDYMKNQLRSLGFGYDWDR  124
            RF+R QG NVL+PMGWDAFGLPAE+ A++    PA  T  NI   K Q+ +LGF+YDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  125  EVTTCKSDYYRWEQWFFTRLYEKGLVYKKNSTVNWDPVDQTVLANEQVI-DGRGWRSGAL  183
            EV T  ++YY+W QW+FT+LYEKGL Y  +  VNW     T +ANE+V+ DG + R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  184  VEQKEIPQWFIKITDYAeellqdleqleeWPDQVRAMQANWIGRSEGVEITFDLASAVND  243
            V +K + QW +KIT YA E L +  +  +WP+ ++ MQ NWIG+S G ++TF +  + + 
Sbjct  184  VVRKPMRQWMLKITAYA-ERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDK-  241

Query  244  IADLTVYTTRPDTFYGVTYVAVAAQHPLAEFAAQSNPDLAAFIEECKNTKVAEAELA---  300
              D+TV+TTRPDT++G TY  +A++H+L +  A + +D A  + + K      ++LA   
Sbjct  242  --DFTVFTTRPDTLFGATYAVLAPEHALVD--AITTSDQAEAVADYKRQASLKSDLARTD  297

Query  301  -TMEKKGFATGFEVIHPLTGEKLPIWVANFVLMDYGSGAVMAVPGHDQRDWEFATKYDLP  359
             + EK G  TG   I+P+ G  +P+W+A++VL  YG+GA+MAVP+HD+RDWEFA +++L 
Sbjct  298  LAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLD  357

Query  360  ITQVIAPNAGDEDKCDLSASAYTEKGSLINSDKFNGLAFDAAFNGIADELEGKGCGKRKV  419
            I  V+     +E       +A+TE G  INSD ++GL   +A+  + + LE+ G G+ +V
Sbjct  358  IIPVLEGGNVEE-------AAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENV  410

Query  420  NYRLRDWGVSRQRYWGAPIPMLNLENGESVPVPADQLPVVLP--EDVEMNGVT-SPIKAD  476
             YRLRDW  SRQRYWG PIP+++ E+G S +VP  +LP+VLP   D+  +G   SP+   
Sbjct  411  TYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANV  470

Query  477  PEWAKTTY-NGEAALRETDTFDTFMESSWYYARYASATNNDAMLDPTSANYWLPVDQYIG  535
             +W   T  +G  + RET+T      SSWYY RY  + N + + D    + WLPVD Y+G
Sbjct  471  TDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVG  530

Query  536  GIEHAILHLLYSRFFHKLLRDEGLVNSDEPFKRLLCQGMVLADSYYREDEAGKKTWFSPT  595
            G EHA+LHLLY+RF HK+L D G+V + EPF++L+ QGM+L+ S YR+  ++        
Sbjct  531  GAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS-YRDSRGAL-------  582

Query  596  EVSTEKDEKGRIVKAWLTADGEEVIHGGMTKMSKSKNNGIDPQEVIDLYGADTVRLFTMF  655
             V+T+K EK     + +  +  E ++ + +KMSKS +N ++P++V++ YGADT+R++ MF
Sbjct  583  -VATDKVEKRD--GSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMF  639

Query  656  AAPPEQTLEWVDSGVEGANRFLRRIWKLVTEHVEKGTPEAIDVKSLSKDQQ-ALRREVHK  714
             +P + ++ W + G+EG+ +FL R+ +L+T             K ++ ++  AL +  + 
Sbjct  640  MGPLDASIAWSEEGLEGSRKFLDRVYRLIT------------TKEITEENSGALDKVYNE  687

Query  715  TIEKVSDDLGRRQTFNTAVAAVMELLNHLQKAPQESAQDIAIMREACESILLLLNPITPH  774
            T+  V++++++ + FNTA+A +M ++N  +K  +       +  +   +++ L+ P++PH
Sbjct  688  TVKAVTEQVDQMK-FNTAIAQLMVFVNAANKEDK-------LFSDYAKGFVQLIAPFAPH  739

Query  775  IAHELWKVL-GHSEDIDSAPWPQADKAALVEDEKLIIVQVNGKVRAKMTiaadaskeaie  833
            +++ELW+ L + +E I   PWP  D + LVE++  I+VQ++GKV+AK+ +A D S+E ++
Sbjct  740  LGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQ  799

Query  834  asakEQPNVQQFIEGKTIRKVIVVPGKLVNIVAN  867
              A  + +VQ  I GK I KVI VP KLVNIV +
Sbjct  800  EVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

1122) leuS in NC_021712


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  542 bits (2047),  Expect = 3e-155, Method: Compositional matrix adjust.
 Identities = 360/874 (42%), Positives = 558/874 (64%), Gaps = 56/874 (6%)

Query  6    YNPKDIEQRVQQYWEENQSFKANDDVEKEKFYCLSMFPYPSGR-LHMGHVRNYTIGDVIS  64
            Y+   IE + Q +W +N++FK+  D  K KFY L MFPYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  65   RFQRMQGKNVLQPMGWDAFGLPAENAAINNNTAPAKWTYSNIDYMKNQLRSLGFGYDWDR  124
            RF+R QG NVL+PMGWDAFGLPAE+ A++    PA  T  NI   K Q+ +LGF+YDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  125  EVTTCKSDYYRWEQWFFTRLYEKGLVYKKNSTVNWDPVDQTVLANEQVI-DGRGWRSGAL  183
            EV T  ++YY+W QW+FT+LYEKGL Y  +  VNW     T +ANE+V+ DG + R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  184  VEQKEIPQWFIKITDYAeellqdleqleeWPDQVRAMQANWIGRSEGVEITFDLASAVND  243
            V +K + QW +KIT YA E L +  +  +WP+ ++ MQ NWIG+S G ++TF +  + + 
Sbjct  184  VVRKPMRQWMLKITAYA-ERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDK-  241

Query  244  IADLTVYTTRPDTFYGVTYVAVAAQHPLAEFAAQSNPDLAAFIEECKNTKVAEAELA---  300
              D+TV+TTRPDT++G TY  +A++H+L +  A + +D A  + + K      ++LA   
Sbjct  242  --DFTVFTTRPDTLFGATYAVLAPEHALVD--AITTSDQAEAVADYKRQASLKSDLARTD  297

Query  301  -TMEKKGFATGFEVIHPLTGEKLPIWVANFVLMDYGSGAVMAVPGHDQRDWEFATKYDLP  359
             + EK G  TG   I+P+ G  +P+W+A++VL  YG+GA+MAVP+HD+RDWEFA +++L 
Sbjct  298  LAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLD  357

Query  360  ITQVIAPNAGDEDKCDLSASAYTEKGSLINSDKFNGLAFDAAFNGIADELEGKGCGKRKV  419
            I  V+     +E       +A+TE G  INSD ++GL   +A+  + + LE+ G G+ +V
Sbjct  358  IIPVLEGGNVEE-------AAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENV  410

Query  420  NYRLRDWGVSRQRYWGAPIPMLNLENGESVPVPADQLPVVLP--EDVEMNGVT-SPIKAD  476
             YRLRDW  SRQRYWG PIP+++ E+G S +VP  +LP+VLP   D+  +G   SP+   
Sbjct  411  TYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANV  470

Query  477  PEWAKTTY-NGEAALRETDTFDTFMESSWYYARYASATNNDAMLDPTSANYWLPVDQYIG  535
             +W   T  +G  + RET+T      SSWYY RY  + N + + D    + WLPVD Y+G
Sbjct  471  TDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVG  530

Query  536  GIEHAILHLLYSRFFHKLLRDEGLVNSDEPFKRLLCQGMVLADSYYREDEAGKKTWFSPT  595
            G EHA+LHLLY+RF HK+L D G+V + EPF++L+ QGM+L+ S YR+  ++        
Sbjct  531  GAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS-YRDSRGAL-------  582

Query  596  EVSTEKDEKGRIVKAWLTADGEEVIHGGMTKMSKSKNNGIDPQEVIDLYGADTVRLFTMF  655
             V+T+K EK     + +  +  E ++ + +KMSKS +N ++P++V++ YGADT+R++ MF
Sbjct  583  -VATDKVEKRD--GSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMF  639

Query  656  AAPPEQTLEWVDSGVEGANRFLRRIWKLVTEHVEKGTPEAIDVKSLSKDQQ-ALRREVHK  714
             +P + ++ W + G+EG+ +FL R+ +L+T             K ++ ++  AL +  + 
Sbjct  640  MGPLDASIAWSEEGLEGSRKFLDRVYRLIT------------TKEITEENSGALDKVYNE  687

Query  715  TIEKVSDDLGRRQTFNTAVAAVMELLNHLQKAPQESAQDIAIMREACESILLLLNPITPH  774
            T+  V++++++ + FNTA+A +M ++N  +K  +       +  +   +++ L+ P++PH
Sbjct  688  TVKAVTEQVDQMK-FNTAIAQLMVFVNAANKEDK-------LFSDYAKGFVQLIAPFAPH  739

Query  775  IAHELWKVL-GHSEDIDSAPWPQADKAALVEDEKLIIVQVNGKVRAKMTiaadaskeaie  833
            +++ELW+ L + +E I   PWP  D + LVE++  I+VQ++GKV+AK+ +A D S+E ++
Sbjct  740  LGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQ  799

Query  834  asakEQPNVQQFIEGKTIRKVIVVPGKLVNIVAN  867
              A  + +VQ  I GK I KVI VP KLVNIV +
Sbjct  800  EVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

1123) leuS in NC_021714


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  542 bits (2047),  Expect = 3e-155, Method: Compositional matrix adjust.
 Identities = 359/874 (42%), Positives = 558/874 (64%), Gaps = 56/874 (6%)

Query  6    YNPKDIEQRVQQYWEENQSFKANDDVEKEKFYCLSMFPYPSGR-LHMGHVRNYTIGDVIS  64
            Y+   IE + Q +W +N++FK+  D  K KFY L MFPYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  65   RFQRMQGKNVLQPMGWDAFGLPAENAAINNNTAPAKWTYSNIDYMKNQLRSLGFGYDWDR  124
            RF+R QG NVL+PMGWDAFGLPAE+ A++    PA  T  NI   K Q+ +LGF+YDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  125  EVTTCKADYYRWEQWFFTRLYEKGLVYKKNSTVNWDPVDQTVLANEQVI-DGRGWRSGAL  183
            EV T  ++YY+W QW+FT+LYEKGL Y  +  VNW     T +ANE+V+ DG + R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  184  VEQKEIPQWFIKITDYAeellqdleqleeWPDQVRAMQANWIGRSEGVEITFDLASAVND  243
            V +K + QW +KIT YA E L +  +  +WP+ ++ MQ NWIG+S G ++TF +  + + 
Sbjct  184  VVRKPMRQWMLKITAYA-ERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDK-  241

Query  244  IADLTVYTTRPDTFYGVTYVAVAAQHPLAEFAAQSNPDLAAFIEECKNTKVAEAELA---  300
              D+TV+TTRPDT++G TY  +A++H+L +  A + +D A  + + K      ++LA   
Sbjct  242  --DFTVFTTRPDTLFGATYAVLAPEHALVD--AITTSDQAEAVADYKRQASLKSDLARTD  297

Query  301  -TMEKKGFATGFEVIHPLTGEKLPIWVANFVLMDYGSGAVMAVPGHDQRDWEFATKYDLP  359
             + EK G  TG   I+P+ G  +P+W+A++VL  YG+GA+MAVP+HD+RDWEFA +++L 
Sbjct  298  LAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLD  357

Query  360  ITQVIAPNAGDEDKCDLSASAYTEKGSLINSDKFNGLAFDAAFNGIADELEGKGCGKRKV  419
            I  V+     +E       +A+TE G  INSD ++GL   +A+  + + LE+ G G+ +V
Sbjct  358  IIPVLEGGNVEE-------AAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENV  410

Query  420  NYRLRDWGVSRQRYWGAPIPMLNLENGESVPVPADQLPVVLP--EDVEMNGVT-SPIKAD  476
             YRLRDW  SRQRYWG PIP+++ E+G S +VP  +LP+VLP   D+  +G   SP+   
Sbjct  411  TYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANV  470

Query  477  PEWAKTTY-NGEAALRETDTFDTFMESSWYYARYASATNNDAMLDPTSANYWLPVDQYIG  535
             +W   T  +G  + RET+T      SSWYY RY  + N + + D    + WLPVD Y+G
Sbjct  471  TDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVG  530

Query  536  GIEHAILHLLYSRFFHKLLRDEGLVNSDEPFKRLLCQGMVLADSYYREDEAGKKTWFSPT  595
            G EHA+LHLLY+RF HK+L D G+V + EPF++L+ QGM+L+ S YR+  ++        
Sbjct  531  GAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS-YRDSRGAL-------  582

Query  596  EVSTEKDDKGRIVKAWLTADGEEVIHGGMTKMSKSKNNGIDPQEVIDLYGADTVRLFTMF  655
             V+T+K +K     + +  +  E ++ + +KMSKS +N ++P++V++ YGADT+R++ MF
Sbjct  583  -VATDKVEKRD--GSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMF  639

Query  656  AAPPEQTLEWVDSGVEGANRFLRRIWKLVTEHVEKGTPEAIDVKSLSKDQQ-ALRREVHK  714
             +P + ++ W + G+EG+ +FL R+ +L+T             K ++ ++  AL +  + 
Sbjct  640  MGPLDASIAWSEEGLEGSRKFLDRVYRLIT------------TKEITEENSGALDKVYNE  687

Query  715  TIEKVSDDLGRRQTFNTAVAAVMELLNHLQKAPQESAQDIAIMREACESILLLLNPITPH  774
            T+  V++++++ + FNTA+A +M ++N  +K  +       +  +   +++ L+ P++PH
Sbjct  688  TVKAVTEQVDQMK-FNTAIAQLMVFVNAANKEDK-------LFSDYAKGFVQLIAPFAPH  739

Query  775  IAHELWKVL-GHSEDIDSAPWPQADKAALVEDEKLIIVQVNGKVRAKMTiaadaskeaie  833
            +++ELW+ L + +E I   PWP  D + LVE++  I+VQ++GKV+AK+ +A D S+E ++
Sbjct  740  LGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQ  799

Query  834  asakEQPNVQQFIEGKTIRKVIVVPGKLVNIVAN  867
              A  + +VQ  I GK I KVI VP KLVNIV +
Sbjct  800  EVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

1124) leuS in NC_021713


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  542 bits (2047),  Expect = 3e-155, Method: Compositional matrix adjust.
 Identities = 359/874 (42%), Positives = 558/874 (64%), Gaps = 56/874 (6%)

Query  6    YNPKDIEQRVQQYWEENQSFKANDDVEKEKFYCLSMFPYPSGR-LHMGHVRNYTIGDVIS  64
            Y+   IE + Q +W +N++FK+  D  K KFY L MFPYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  65   RFQRMQGKNVLQPMGWDAFGLPAENAAINNNTAPAKWTYSNIDYMKNQLRSLGFGYDWDR  124
            RF+R QG NVL+PMGWDAFGLPAE+ A++    PA  T  NI   K Q+ +LGF+YDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  125  EVTTCKADYYRWEQWFFTRLYEKGLVYKKNSTVNWDPVDQTVLANEQVI-DGRGWRSGAL  183
            EV T  ++YY+W QW+FT+LYEKGL Y  +  VNW     T +ANE+V+ DG + R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  184  VEQKEIPQWFIKITDYAeellqdleqleeWPDQVRAMQANWIGRSEGVEITFDLASAVND  243
            V +K + QW +KIT YA E L +  +  +WP+ ++ MQ NWIG+S G ++TF +  + + 
Sbjct  184  VVRKPMRQWMLKITAYA-ERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDK-  241

Query  244  IADLTVYTTRPDTFYGVTYVAVAAQHPLAEFAAQSNPDLAAFIEECKNTKVAEAELA---  300
              D+TV+TTRPDT++G TY  +A++H+L +  A + +D A  + + K      ++LA   
Sbjct  242  --DFTVFTTRPDTLFGATYAVLAPEHALVD--AITTSDQAEAVADYKRQASLKSDLARTD  297

Query  301  -TMEKKGFATGFEVIHPLTGEKLPIWVANFVLMDYGSGAVMAVPGHDQRDWEFATKYDLP  359
             + EK G  TG   I+P+ G  +P+W+A++VL  YG+GA+MAVP+HD+RDWEFA +++L 
Sbjct  298  LAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLD  357

Query  360  ITQVIAPNAGDEDKCDLSASAYTEKGSLINSDKFNGLAFDAAFNGIADELEGKGCGKRKV  419
            I  V+     +E       +A+TE G  INSD ++GL   +A+  + + LE+ G G+ +V
Sbjct  358  IIPVLEGGNVEE-------AAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENV  410

Query  420  NYRLRDWGVSRQRYWGAPIPMLNLENGESVPVPADQLPVVLP--EDVEMNGVT-SPIKAD  476
             YRLRDW  SRQRYWG PIP+++ E+G S +VP  +LP+VLP   D+  +G   SP+   
Sbjct  411  TYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANV  470

Query  477  PEWAKTTY-NGEAALRETDTFDTFMESSWYYARYASATNNDAMLDPTSANYWLPVDQYIG  535
             +W   T  +G  + RET+T      SSWYY RY  + N + + D    + WLPVD Y+G
Sbjct  471  TDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVG  530

Query  536  GIEHAILHLLYSRFFHKLLRDEGLVNSDEPFKRLLCQGMVLADSYYREDEAGKKTWFSPT  595
            G EHA+LHLLY+RF HK+L D G+V + EPF++L+ QGM+L+ S YR+  ++        
Sbjct  531  GAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS-YRDSRGAL-------  582

Query  596  EVSTEKDDKGRIVKAWLTADGEEVIHGGMTKMSKSKNNGIDPQEVIDLYGADTVRLFTMF  655
             V+T+K +K     + +  +  E ++ + +KMSKS +N ++P++V++ YGADT+R++ MF
Sbjct  583  -VATDKVEKRD--GSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMF  639

Query  656  AAPPEQTLEWVDSGVEGANRFLRRIWKLVTEHVEKGTPEAIDVKSLSKDQQ-ALRREVHK  714
             +P + ++ W + G+EG+ +FL R+ +L+T             K ++ ++  AL +  + 
Sbjct  640  MGPLDASIAWSEEGLEGSRKFLDRVYRLIT------------TKEITEENSGALDKVYNE  687

Query  715  TIEKVSDDLGRRQTFNTAVAAVMELLNHLQKAPQESAQDIAIMREACESILLLLNPITPH  774
            T+  V++++++ + FNTA+A +M ++N  +K  +       +  +   +++ L+ P++PH
Sbjct  688  TVKAVTEQVDQMK-FNTAIAQLMVFVNAANKEDK-------LFSDYAKGFVQLIAPFAPH  739

Query  775  IAHELWKVL-GHSEDIDSAPWPQADKAALVEDEKLIIVQVNGKVRAKMTiaadaskeaie  833
            +++ELW+ L + +E I   PWP  D + LVE++  I+VQ++GKV+AK+ +A D S+E ++
Sbjct  740  LGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQ  799

Query  834  asakEQPNVQQFIEGKTIRKVIVVPGKLVNIVAN  867
              A  + +VQ  I GK I KVI VP KLVNIV +
Sbjct  800  EVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

1125) leuS in NC_010995


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  542 bits (2046),  Expect = 3e-155, Method: Compositional matrix adjust.
 Identities = 364/875 (42%), Positives = 566/875 (65%), Gaps = 60/875 (6%)

Query  5    YNPAEVEAQAQQYWEEHQSFNVIEDPGKEKFYCLAMFPYPSGK-LHMGHVRNYTITDVIA  63
            Y+ + +E++ Q +W ++++F+   D++K KFY L MFPYPSG  LH+GH   YT TD+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMQGKNVLHPMGWDAFGLPAENAALKHNTAPAKWTYSNTDHMRNQLKQLGFGFDWSR  123
            R++R QG NVLHPMGWDAFGLPAE+ A+     PA  T  N  + + Q++ LGF++DW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELTTCKPEYYQWEQWFFTRLYEKGLVYKKMSTVNWDPIDQTVLANEQVI-DGRGWRSGAL  182
            E+ T  P+YY+W QW+FT+LYEKGL Y     VNW     T +ANE+V+ DG + R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITDYAEELLNDLDKLPNWPEQVKTMQRNWIGKSRGLEMRFDLQSPVGE  242
            V RK + QW +KIT YAE LL+DL+ + +WPE +K MQRNWIGKS G ++ F ++    +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  FTSFDIYTTRPDTLMGVTYVSLAAEHPIAKYLADSNPALAQFIADCKVQSVAEADMA---  299
            FT   ++TTRPDTL G TY  LA+EH++   ++ S+   A+ +AD K Q+   +D+A   
Sbjct  243  FT---VFTTRPDTLFGATYAVLAPEHALVDAITTSDQ--AEAVADYKRQASLKSDLARTD  297

Query  300  -TMEKKGMDTGIKALHPITGEPVAVWVANYVLMDYGSGAVMAVPAHDQRDYEFAQKYHLG  358
             + EK G+ TG  A++P+ G  ++VW+A+YVL  YG+GA+MAVPAHD+RD EFA++++L+
Sbjct  298  LAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLD  357

Query  359  ITQVIAPQNGETIDLSQAAFTDKGVLVNSGEYDGLDFNAAFDAIASTLEMANKGRVKTNY  418
            I  V+     E  ++ +AAFT+ G+ +NS+  DGLD  +A+  +   LE    G  +  Y
Sbjct  358  IIPVL-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTY  412

Query  419  RLRDWGVSRQRYWGAPIPMFNLPEGGEIPVPAHKLPILLP--EEVVMNGV-QSPIKADPE  475
            RLRDW  SRQRYWG PIP+++  +G   +VP   LP++LP   ++  +G  +SP+    +
Sbjct  413  RLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTD  472

Query  476  W----KKDELDGQYVERETDTFDTFMESSWYYARYTCPNFTDGMINKAAADYWLPVDQYV  531
            W    + D + G+   RET+T      SSWYY RY  P+ T+ + +      WLPVD YV
Sbjct  473  WLEVTREDGVKGR---RETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYV  529

Query  532  GGIEHAILHLLYSRFFHKLMRDEGLVSGDEPFERLLCQGMVNAESFFIKSEGKENWIEPE  591
            GG EHA+LHLLY+RF HK++ D G+V+  EPF++L+ QGM+ + S+    +++   +  +
Sbjct  530  GGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY---RDSRGALVATD  586

Query  592  NVVIERDDKGRFIAAKHKITGDAVEFGGVIKMSKSKANGVDPESVINQYGADTVRLFTMF  651
            +V  E+ D G F+   H  TG+ +E  +  KMSKS  N V+P+ V++QYGADT+R++ MF
Sbjct  587  KV--EKRD-GSFF---HVETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMF  639

Query  652  AAPPEQSLEWSDSGVEGASRFLRRLWKAVEG-HINAGTPGKLDAASLPQQQKDLRRKTHE  710
             +P + S+ WS+ G+EG+ +FL R+ + +   +I    +G LD            +  +E
Sbjct  640  MGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALD------------KVYNE  687

Query  711  TIQKVSDDYGRRQTFNTAIAAVMELLNETSKLSDRANPQGlaverealeaailllaPIVP  770
            T++ V+++ ++ + FNTAIA +M ++N ++K  D+  ++          + + L+AP+ P
Sbjct  688  TVKAVTEQVDQMK-FNTAIAQLMVFVNAANK-EDKLFSD-------YAKGFVQLIAPFAP  738

Query  771  HITQALWIELGNSGIPLN-QPWPTLDESALVRSTIEVVVQVNGKLRGKIDAAVDAPKELL  829
            H+ + LW  L  SG +++  PWP+ DES LV + +E+VVQ++GK+++K+  A D ++E L
Sbjct  739  HLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREEL  798

Query  830  EQIAVQQENVQKFLEGVTVRKVIVVPNKLVNIVAN  864
            +++A+ +E+VQ  + G  + KVI VPNKLVNIV +
Sbjct  799  QEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

1126) leuS in NC_011993


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  542 bits (2046),  Expect = 3e-155, Method: Compositional matrix adjust.
 Identities = 360/865 (42%), Positives = 556/865 (65%), Gaps = 46/865 (5%)

Query  5    YRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIA  63
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKTMQRNWIGRSEGVEITFNVKDYDNT  242
            V RK + QW +KITAYA+ LL+DL+ +D WP+++K MQRNWIG+S G ++TF+VKD D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGCTYLAVAAGHPLAQ--KAAENNPELAAFIDECR-NTKVAEAEMATME  299
            +TV+TTRPDT+ G TY  +A+ H+L +   ++++   +A +  +   ++ +A +++A  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGVDTGFKAVHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPV  359
            K GV TG  A++P+ G E+PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L+I PV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  360  ILAADGSEPDLSQQALTEKGVLFNSGEFNGLDHEAAFNAIADKLTEMGVGERKVNYRLRD  419
            +        ++ + A+TE G+ +NS+ ++GLD  +A+  + + L   GVG+ +V YRLRD
Sbjct  362  L-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMVTLEDGTVMPTPDDQLPVILP--EDVVMDGIT-SPIKADPEWAKT  476
            W  SRQRYWG PIP++  EDGT  + P+ +LP++LP   D+   G   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  T-VNGMPALRETDTFDTFMESSWYYARYTCPEYKEGMLDSKAANYWLPVDIYIGGIEHAI  535
            T  +G+ + RET+T      SSWYY RY  P+  E + D    + WLPVDIY+GG EHA+
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVER  595
            +HLLY RF HK++ D G+V + EP ++L+ QGM+L+ ++      + R  + + D +  R
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEKR  591

Query  596  DEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMT  655
            D  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D +
Sbjct  592  D--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  656  LEWQESGVEGANRFLKRVWKLVYEHTAKGDVAALNVDVLTEDQKALRRDVHKTIAKVTDD  715
            + W E G+EG+ +FL RV +L+   T+K        ++  E+  AL +  + T+  VT++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLI---TTK--------EITEENSGALDKVYNETVKAVTEQ  695

Query  716  IGRRQTFNTAIAAIMELMNKLAKAPTDGEQDRALMQEALLAVVRMLNPFTPHICFTLWQE  775
            +++ + FNTAIA +M ++N        ++++  L  +   + V+++ PF+PH+   LWQ 
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  776  LKGEGD-IDNAPWPVADEKAMVEDSTLVVVQVNGKVRAKITVPVDATEEQVRERAGQEHL  834
            L + G+ I   PWP  DE  +VE+   +VVQ++GKV+AK+ V+ D + E+++E A  ++ 
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  835  VAKYLDGVTVRKVIYVPGKLLNLVV  859
            V   + G  + KVI VP KL+N+V+
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVI  832

1127) leuS in NC_014500


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  542 bits (2047),  Expect = 3e-155, Method: Compositional matrix adjust.
 Identities = 352/866 (41%), Positives = 556/866 (65%), Gaps = 48/866 (5%)

Query  5    YRPEEIEAHVQLHWQEKQTFKVTEEPGKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIS  63
            Y    IE+  Q  W +++TFK   +++K K+Y L M+PYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYANIEYMKNQLKLLGFGYDWDR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T  NI   K Q++ LGF+YDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVATCKPDYYRWEQWFFTKLYEKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            EV T  P+YY+W QW+FTKLYEKGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADELLNDLDTLESWPEQVKTMQRNWIGRSEGVEITFDVADSEEK  242
            V RK + QW +KITAYA+ LL+DL+ ++ WPE +K MQRNWIG+S G ++TF V D++  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LSVYTTRPDTFMGVTYVAVAAGHPLAQ--KAAENNPALRDFIAECG-NTKMAEADMATME  299
            ++V+TTRPDT+ G TY  +A+ H+L +   ++++  A+ D+  + + ++ +A +D+A  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGIATGLFAVHPLTGENVPVWAANFVLMEYGTGAVMAVPGHDQRDWEFAHKYNLPVKPV  359
            K G+ TG +A++P+ G ++PVW A++VL  YGTGA+MAVP+HD+RDWEFA ++NL + PV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  360  ILMADGSEPDLSAQAQTEKGRLFNSGEF-DGLDFDAAFNAIADKLVSQGVGQRKVNYRLR  418
            +  ++  E+ ++ ++      L  +++F DGLD  +A+  + + L ++GVG+ +V YRLR
Sbjct  362  LEGGNVEEAAFTEDG------LHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  419  DWGVSRQRYWGAPIPMMTLEDGTVVPTPEDQLPVILP--EDVVMDGIT-SPIKADPEWAK  475
            DW  SRQRYWG PIP++  EDGT  + PE +LP++LP   D+   G   SP+    +W  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  476  TTF-NGQPALRETDTFDTFMESSWYYARYTCPQYDQGMLDPAAANYWLPVDQYVGGIEHA  534
             T  +G  + RET+T      SSWYY RY  P+  + + D    + WLPVD YVGG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  535  ILHLMYFRFFHKLMRDAGLVNSNEPAKRLLCQGMVLADAFYHAGNNGERIWVSPSDVTLE  594
            +LHL+Y RF HK++ D G+V ++EP ++L+ QGM+L+ + Y+ +  +         V+ +
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS-YRDSRGAL--------VATD  586

Query  595  RDDKGRITKAFDKDGRELVYAGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPAEM  654
            + +K R    F+ +  E +  + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P + 
Sbjct  587  KVEK-RDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  655  TLEWQESGVEGANRFLKRVWKQVYDHTGKGAAQPLDTAALTEDQKALRRDLHKTIAKVTD  714
            ++ W E G+EG+ +FL RV + +   T K  ++        E+  AL +  + T+  VT+
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLI---TTKEITE--------ENSGALDKVYNETVKAVTE  694

Query  715  DIGRRQTFNTAIAAIMELMNKLAKASQESEQDRALTQETLLAVVRMLYPFTPHACFVLWR  774
            ++++ + FNTAIA +M ++N        ++++  L  +   + V+++ PF+PH    LW+
Sbjct  695  QVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  775  ELQGEGD-IDLAPWPVADEQAMVEDSRLVVVQVNGKVRGKITVAADATEQQVRDRAAQEP  833
             L + G+ I   PWP  DE  +VE+   +VVQ++GKV++K+ VA D + +++++ A  + 
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  834  LVAKYLDGVTVRKVIFVPGKLLNLVV  859
             V   + G  + KVI VP KL+N+V+
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVI  832

1128) Desal_0650 in NC_012881


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  542 bits (2046),  Expect = 4e-155, Method: Compositional matrix adjust.
 Identities = 364/871 (42%), Positives = 544/871 (63%), Gaps = 78/871 (8%)

Query  1    MGFGKYEPELIENKWQKEWTEKGAFNVEADESRPKYYVLEMFPYPSGK-IHMGHVRNYSI  59
            M F  Y+   IE KWQ  W+++ +F+  +D S+PK+Y L+MFPYPSG  +H+GH   Y+ 
Sbjct  1    MTF--YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTA  58

Query  60   GDVVARYKRMKGFNVLHPMGWDAFGLPAENAAIKHNTHPAEWTYANIDDMRTQLKRLGYS  119
             D+++R+KR +G NVLHPMGWDAFGLPAE+ A+    +PAE T  NI + + Q++ LG+S
Sbjct  59   TDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFS  118

Query  120  YDWRRELATCHPGYYKWEQQFFLKFLEKGLVYRKKSPVNWCETCHTVLANEQV-EEGLCW  178
            YDW RE+ T +P YYKW Q +F K+ EKGL Y    PVNW E   T +ANE+V  +G   
Sbjct  119  YDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSE  178

Query  179  RCDTEVIQKELSQWFMRITDYAeelleslgeleggWPERVITMQRNWIGKSIGAELDFEV  238
            R +  V++K + QW ++IT YA       +  E +WPE +  MQRNWIGKS GA++ F V
Sbjct  179  RGGYPVVRKPMRQWMLKITAYA--ERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKV  236

Query  239  ENSDETISVFTTRPDTLFGATFMSLAAEHPMVEKLIEGKPEADKVREFVHKVSNMDRIVR  298
             ++D  ++VFTTRPDTLFGAT+  LA+EH++V+  I    +A+ V ++ ++ S    + R
Sbjct  237  KDTDKDFTVFTTRPDTLFGATYAVLAPEHALVDA-ITTSDQAEAVADYKRQASLKSDLAR  295

Query  299  GADDLEKEGVFTGAYCINPLNGQKMPIYVANFVLMGYGTGAVMAVPAHDQRDFEFAKKYD  358
                 EK GV TG+Y INP+NG+ MP+ +A++VL +YGTGA+MAVPAHD+RD EFAK+++
Sbjct  296  TDLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFN  355

Query  359  LPKQVVIQPEGETLNVAEMEEAYTAPGVLVNSGEFDGMPNEDAKGAIVDFLGKSGKGKKS  418
            L  +++   EG  ++    E A+T  G+ +NS+ +DG+ +  A + +V+ L   G G+ +
Sbjct  356  L--DIIPVLEGGNVE----EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNEN  409

Query  419  INYRLRDWNISRQRFWGSPIPVIYCDECGIVPVPEQDLPVVLP--EDAVMNEDGRSPLPD  476
            + YRLRDW +SRQR+WG PIP+I  ++    +VPE +LP+VLP   D   +  G SPL++
Sbjct  410  VTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLAN  469

Query  477  MESFHKVTCPKCGKMAQRETDTMDTFVESSWYFMRYTDSRKADAPFDSKSLEYWTPVDQY  536
            +     VT     K ++RET+TM     SSWY++RY D+++++   D   L  W PVD Y
Sbjct  470  VTDWLEVTREDGVK-GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIY  528

Query  537  IGGIEHAILHLLYARFFTKILRDEGYTELSEPFKNLLTQGMVL-----------------  579
            +GG EHA+LHLLYARF  K+L D G     EPF++L+ QGM+L                 
Sbjct  529  VGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKV  588

Query  580  --KDG---------------AKMSKSKGNVVDPNAMINKYGADATRLFILFASPPEKDLE  622
              +DG               AKMSKS  NVV+P+ ++++YGAD+ R++ +F +P +  + 
Sbjct  589  EKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIA  648

Query  623  WSDQGLEGAHRFLNRIWRLAEEFEGKLSATGACAKPSMELSSDAKKLRLKEHETVKRASR  682
            WS++GLEG+++FL+R+ RL    E     +GA  K                +ETVK  + 
Sbjct  649  WSEEGLEGSRKFLDRVYRLITTKEITEENSGALDKVY--------------NETVKAVTE  694

Query  683  DMENKFQFNTVIAASMELVNEIYSLKDKLMETEDGRFALSSAYSTVLT-VLSPIAPHICE  741
            ++++  +FNT IA  M +VN          + ED  F   S Y+  +  +++P+APH+ E
Sbjct  695  QVDQM-KFNTAIAQLMVFVNAA--------NKEDKLF---SDYAKGFVQLIAPFAPHLGE  742

Query  742  ELWAAMGYEG-YIAEVEWPEHDEAALVTDEILIIIQVNGKMRGKLSVPAAASKEEIEETA  800
            ELW A+   G  I+ V WP  DE+ LV +++ I++Q++GK+++KL V+   S+EE++E A
Sbjct  743  ELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVA  802

Query  801  LAHENVTKHTDGKTIRKVIVVPGKLINIVAN  831
            LA+E+V  +  GK I KVI VP KL+NIV +
Sbjct  803  LANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

1129) leuS in NC_008563


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  542 bits (2045),  Expect = 4e-155, Method: Compositional matrix adjust.
 Identities = 361/865 (42%), Positives = 555/865 (65%), Gaps = 46/865 (5%)

Query  52   YRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIA  110
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  111  RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSR  170
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  171  ELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  229
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  230  VERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKTMQRNWIGRSEGVEITFNVKDYDNT  289
            V RK + QW +KITAYA+ LL+DL+ +D WP+++K MQRNWIG+S G ++TF+VKD D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  290  LTVYTTRPDTFMGCTYLAVAAGHPLAQ--KAAENNPELAAFIDECR-NTKVAEAEMATME  346
            +TV+TTRPDT+ G TY  +A+ H+L +   ++++   +A +  +   ++ +A +++A  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  347  KKGVDTGFKAVHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPV  406
            K GV TG  A++P+ G E+PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L+I PV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  407  ILAADGSEPDLSQQALTEKGVLFNSGEFNGLDHEAAFNAIADKLTEMGVGERKVNYRLRD  466
            +        ++ + A+TE G+ +NS+ ++GLD  +A+  + + L   GVG+ +V YRLRD
Sbjct  362  L-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  467  WGVSRQRYWGAPIPMVTLEDGTVMPTPDDQLPVILP--EDVVMDGIT-SPIKADPEWAKT  523
            W  SRQRYWG PIP++  EDGT  + P+ +LP++LP   D+   G   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  524  T-VNGMPALRETDTFDTFMESSWYYARYTCPEYKEGMLDSKAANYWLPVDIYIGGIEHAI  582
            T  +G+ + RET+T      SSWYY RY  P+  E + D    + WLPVDIY+GG EHA+
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  583  MHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVER  642
            +HLLY RF HK++ D G+V + EP ++L+ QGM+L+ +  Y +  G    + + D +  R
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS--YRDSRGA---LVATDKVEKR  591

Query  643  DEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMT  702
            D  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D +
Sbjct  592  D--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  703  LEWQESGVEGANRFLKRVWKLVYEHTAKGDVAALNVDALTEDQKALRRDVHKTIAKVTDD  762
            + W E G+EG+ +FL RV +L+   T+K        +   E+  AL +  + T+  VT++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLI---TTK--------EITEENSGALDKVYNETVKAVTEQ  695

Query  763  IGRRQTFNTAIAAIMELMNKLAKAPTDGEQDRALMQEALLAVVRMLNPFTPHICFTLWQE  822
            +++ + FNTAIA +M ++N        ++++  L  +   + V+++ PF+PH+   LWQ 
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  823  LKGEGD-IDNAPWPVADEKAMVEDSTLVVVQVNGKVRAKITVPVDATEEQVRERAGQEHL  881
            L + G+ I   PWP  DE  +VE+   +VVQ++GKV+AK+ V+ D + E+++E A  ++ 
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  882  VAKYLDGVTVRKVIYVPGKLLNLVV  906
            V   + G  + KVI VP KL+N+V+
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVI  832

1130) leuS in NC_012759


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  542 bits (2045),  Expect = 4e-155, Method: Compositional matrix adjust.
 Identities = 362/865 (42%), Positives = 557/865 (65%), Gaps = 46/865 (5%)

Query  5    YRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIA  63
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKTMQRNWIGRSEGVEITFNVNDYDNT  242
            V RK + QW +KITAYA+ LL+DL+ +D WP+++K MQRNWIG+S G ++TF+V+D D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGCTYLAVAAGHPLAQ--KAAENNPELAAFIDECR-NTKVAEAEMATME  299
            +TV+TTRPDT+ G TY  +A+ H+L +   ++++   +A +  +   ++ +A +++A  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGVDTGFKAVHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPV  359
            K GV TG  A++P+ G E+PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L+I PV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  360  ILAADGSEPDLSQQALTEKGVLFNSGEFNGLDHEAAFNAIADKLTAMGVGERKVNYRLRD  419
            +        ++ + A+TE G+ +NS+ ++GLD  +A+  + + L A GVG+ +V YRLRD
Sbjct  362  L-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMVTLEDGTVMPTPDDQLPVILP--EDVVMDGIT-SPIKADPEWAKT  476
            W  SRQRYWG PIP++  EDGT  + P+ +LP++LP   D+   G   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  T-VNGMPALRETDTFDTFMESSWYYARYTCPQYKEGMLDSEAANYWLPVDIYIGGIEHAI  535
            T  +G+ + RET+T      SSWYY RY  P+  E + D E  + WLPVDIY+GG EHA+
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVER  595
            +HLLY RF HK++ D G+V + EP ++L+ QGM+L+ ++      + R  + + D +  R
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEKR  591

Query  596  DEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMT  655
            D  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D +
Sbjct  592  D--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  656  LEWQESGVEGANRFLKRVWKLVYEHTAKGDVAALNVDALTENQKALRRDVHKTIAKVTDD  715
            + W E G+EG+ +FL RV +L+   T+K        +   EN  AL +  + T+  VT++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLI---TTK--------EITEENSGALDKVYNETVKAVTEQ  695

Query  716  IGRRQTFNTAIAAIMELMNKLAKAPTDGEQDRALMQEALLAVVRMLNPFTPHICFTLWQE  775
            +++ + FNTAIA +M ++N        ++++  L  +   + V+++ PF+PH+   LWQ 
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  776  LKGEGD-IDNAPWPVADEKAMVEDSTLVVVQVNGKVRAKITVPVDATEEQVRERAGQEHL  834
            L + G+ I   PWP  DE  +VE+   +VVQ++GKV+AK+ V+ D + E+++E A  ++ 
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  835  VAKYLDGVTVRKVIYVPGKLLNLVV  859
            V   + G  + KVI VP KL+N+V+
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVI  832

1131) EcDH1_2984 in NC_017625


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  542 bits (2045),  Expect = 4e-155, Method: Compositional matrix adjust.
 Identities = 362/865 (42%), Positives = 557/865 (65%), Gaps = 46/865 (5%)

Query  5    YRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIA  63
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKTMQRNWIGRSEGVEITFNVNDYDNT  242
            V RK + QW +KITAYA+ LL+DL+ +D WP+++K MQRNWIG+S G ++TF+V+D D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGCTYLAVAAGHPLAQ--KAAENNPELAAFIDECR-NTKVAEAEMATME  299
            +TV+TTRPDT+ G TY  +A+ H+L +   ++++   +A +  +   ++ +A +++A  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGVDTGFKAVHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPV  359
            K GV TG  A++P+ G E+PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L+I PV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  360  ILAADGSEPDLSQQALTEKGVLFNSGEFNGLDHEAAFNAIADKLTAMGVGERKVNYRLRD  419
            +        ++ + A+TE G+ +NS+ ++GLD  +A+  + + L A GVG+ +V YRLRD
Sbjct  362  L-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMVTLEDGTVMPTPDDQLPVILP--EDVVMDGIT-SPIKADPEWAKT  476
            W  SRQRYWG PIP++  EDGT  + P+ +LP++LP   D+   G   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  T-VNGMPALRETDTFDTFMESSWYYARYTCPQYKEGMLDSEAANYWLPVDIYIGGIEHAI  535
            T  +G+ + RET+T      SSWYY RY  P+  E + D E  + WLPVDIY+GG EHA+
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVER  595
            +HLLY RF HK++ D G+V + EP ++L+ QGM+L+ ++      + R  + + D +  R
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEKR  591

Query  596  DEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMT  655
            D  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D +
Sbjct  592  D--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  656  LEWQESGVEGANRFLKRVWKLVYEHTAKGDVAALNVDALTENQKALRRDVHKTIAKVTDD  715
            + W E G+EG+ +FL RV +L+   T+K        +   EN  AL +  + T+  VT++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLI---TTK--------EITEENSGALDKVYNETVKAVTEQ  695

Query  716  IGRRQTFNTAIAAIMELMNKLAKAPTDGEQDRALMQEALLAVVRMLNPFTPHICFTLWQE  775
            +++ + FNTAIA +M ++N        ++++  L  +   + V+++ PF+PH+   LWQ 
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  776  LKGEGD-IDNAPWPVADEKAMVEDSTLVVVQVNGKVRAKITVPVDATEEQVRERAGQEHL  834
            L + G+ I   PWP  DE  +VE+   +VVQ++GKV+AK+ V+ D + E+++E A  ++ 
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  835  VAKYLDGVTVRKVIYVPGKLLNLVV  859
            V   + G  + KVI VP KL+N+V+
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVI  832

1132) leuS in NC_017638


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  542 bits (2045),  Expect = 4e-155, Method: Compositional matrix adjust.
 Identities = 362/865 (42%), Positives = 557/865 (65%), Gaps = 46/865 (5%)

Query  5    YRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIA  63
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKTMQRNWIGRSEGVEITFNVNDYDNT  242
            V RK + QW +KITAYA+ LL+DL+ +D WP+++K MQRNWIG+S G ++TF+V+D D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGCTYLAVAAGHPLAQ--KAAENNPELAAFIDECR-NTKVAEAEMATME  299
            +TV+TTRPDT+ G TY  +A+ H+L +   ++++   +A +  +   ++ +A +++A  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGVDTGFKAVHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPV  359
            K GV TG  A++P+ G E+PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L+I PV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  360  ILAADGSEPDLSQQALTEKGVLFNSGEFNGLDHEAAFNAIADKLTAMGVGERKVNYRLRD  419
            +        ++ + A+TE G+ +NS+ ++GLD  +A+  + + L A GVG+ +V YRLRD
Sbjct  362  L-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMVTLEDGTVMPTPDDQLPVILP--EDVVMDGIT-SPIKADPEWAKT  476
            W  SRQRYWG PIP++  EDGT  + P+ +LP++LP   D+   G   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  T-VNGMPALRETDTFDTFMESSWYYARYTCPQYKEGMLDSEAANYWLPVDIYIGGIEHAI  535
            T  +G+ + RET+T      SSWYY RY  P+  E + D E  + WLPVDIY+GG EHA+
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVER  595
            +HLLY RF HK++ D G+V + EP ++L+ QGM+L+ ++      + R  + + D +  R
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEKR  591

Query  596  DEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMT  655
            D  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D +
Sbjct  592  D--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  656  LEWQESGVEGANRFLKRVWKLVYEHTAKGDVAALNVDALTENQKALRRDVHKTIAKVTDD  715
            + W E G+EG+ +FL RV +L+   T+K        +   EN  AL +  + T+  VT++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLI---TTK--------EITEENSGALDKVYNETVKAVTEQ  695

Query  716  IGRRQTFNTAIAAIMELMNKLAKAPTDGEQDRALMQEALLAVVRMLNPFTPHICFTLWQE  775
            +++ + FNTAIA +M ++N        ++++  L  +   + V+++ PF+PH+   LWQ 
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  776  LKGEGD-IDNAPWPVADEKAMVEDSTLVVVQVNGKVRAKITVPVDATEEQVRERAGQEHL  834
            L + G+ I   PWP  DE  +VE+   +VVQ++GKV+AK+ V+ D + E+++E A  ++ 
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  835  VAKYLDGVTVRKVIYVPGKLLNLVV  859
            V   + G  + KVI VP KL+N+V+
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVI  832

1133) ETEC_0670 in NC_017633


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  542 bits (2045),  Expect = 4e-155, Method: Compositional matrix adjust.
 Identities = 362/865 (42%), Positives = 557/865 (65%), Gaps = 46/865 (5%)

Query  5    YRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIA  63
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKTMQRNWIGRSEGVEITFNVNDYDNT  242
            V RK + QW +KITAYA+ LL+DL+ +D WP+++K MQRNWIG+S G ++TF+V+D D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGCTYLAVAAGHPLAQ--KAAENNPELAAFIDECR-NTKVAEAEMATME  299
            +TV+TTRPDT+ G TY  +A+ H+L +   ++++   +A +  +   ++ +A +++A  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGVDTGFKAVHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPV  359
            K GV TG  A++P+ G E+PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L+I PV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  360  ILAADGSEPDLSQQALTEKGVLFNSGEFNGLDHEAAFNAIADKLTAMGVGERKVNYRLRD  419
            +        ++ + A+TE G+ +NS+ ++GLD  +A+  + + L A GVG+ +V YRLRD
Sbjct  362  L-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMVTLEDGTVMPTPDDQLPVILP--EDVVMDGIT-SPIKADPEWAKT  476
            W  SRQRYWG PIP++  EDGT  + P+ +LP++LP   D+   G   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  T-VNGMPALRETDTFDTFMESSWYYARYTCPQYKEGMLDSEAANYWLPVDIYIGGIEHAI  535
            T  +G+ + RET+T      SSWYY RY  P+  E + D E  + WLPVDIY+GG EHA+
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVER  595
            +HLLY RF HK++ D G+V + EP ++L+ QGM+L+ ++      + R  + + D +  R
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEKR  591

Query  596  DEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMT  655
            D  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D +
Sbjct  592  D--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  656  LEWQESGVEGANRFLKRVWKLVYEHTAKGDVAALNVDALTENQKALRRDVHKTIAKVTDD  715
            + W E G+EG+ +FL RV +L+   T+K        +   EN  AL +  + T+  VT++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLI---TTK--------EITEENSGALDKVYNETVKAVTEQ  695

Query  716  IGRRQTFNTAIAAIMELMNKLAKAPTDGEQDRALMQEALLAVVRMLNPFTPHICFTLWQE  775
            +++ + FNTAIA +M ++N        ++++  L  +   + V+++ PF+PH+   LWQ 
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  776  LKGEGD-IDNAPWPVADEKAMVEDSTLVVVQVNGKVRAKITVPVDATEEQVRERAGQEHL  834
            L + G+ I   PWP  DE  +VE+   +VVQ++GKV+AK+ V+ D + E+++E A  ++ 
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  835  VAKYLDGVTVRKVIYVPGKLLNLVV  859
            V   + G  + KVI VP KL+N+V+
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVI  832

1134) leuS in NC_010473


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  542 bits (2045),  Expect = 4e-155, Method: Compositional matrix adjust.
 Identities = 362/865 (42%), Positives = 557/865 (65%), Gaps = 46/865 (5%)

Query  5    YRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIA  63
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKTMQRNWIGRSEGVEITFNVNDYDNT  242
            V RK + QW +KITAYA+ LL+DL+ +D WP+++K MQRNWIG+S G ++TF+V+D D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGCTYLAVAAGHPLAQ--KAAENNPELAAFIDECR-NTKVAEAEMATME  299
            +TV+TTRPDT+ G TY  +A+ H+L +   ++++   +A +  +   ++ +A +++A  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGVDTGFKAVHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPV  359
            K GV TG  A++P+ G E+PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L+I PV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  360  ILAADGSEPDLSQQALTEKGVLFNSGEFNGLDHEAAFNAIADKLTAMGVGERKVNYRLRD  419
            +        ++ + A+TE G+ +NS+ ++GLD  +A+  + + L A GVG+ +V YRLRD
Sbjct  362  L-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMVTLEDGTVMPTPDDQLPVILP--EDVVMDGIT-SPIKADPEWAKT  476
            W  SRQRYWG PIP++  EDGT  + P+ +LP++LP   D+   G   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  T-VNGMPALRETDTFDTFMESSWYYARYTCPQYKEGMLDSEAANYWLPVDIYIGGIEHAI  535
            T  +G+ + RET+T      SSWYY RY  P+  E + D E  + WLPVDIY+GG EHA+
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVER  595
            +HLLY RF HK++ D G+V + EP ++L+ QGM+L+ ++      + R  + + D +  R
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEKR  591

Query  596  DEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMT  655
            D  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D +
Sbjct  592  D--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  656  LEWQESGVEGANRFLKRVWKLVYEHTAKGDVAALNVDALTENQKALRRDVHKTIAKVTDD  715
            + W E G+EG+ +FL RV +L+   T+K        +   EN  AL +  + T+  VT++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLI---TTK--------EITEENSGALDKVYNETVKAVTEQ  695

Query  716  IGRRQTFNTAIAAIMELMNKLAKAPTDGEQDRALMQEALLAVVRMLNPFTPHICFTLWQE  775
            +++ + FNTAIA +M ++N        ++++  L  +   + V+++ PF+PH+   LWQ 
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  776  LKGEGD-IDNAPWPVADEKAMVEDSTLVVVQVNGKVRAKITVPVDATEEQVRERAGQEHL  834
            L + G+ I   PWP  DE  +VE+   +VVQ++GKV+AK+ V+ D + E+++E A  ++ 
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  835  VAKYLDGVTVRKVIYVPGKLLNLVV  859
            V   + G  + KVI VP KL+N+V+
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVI  832

1135) leuS in NC_010473


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  542 bits (2045),  Expect = 4e-155, Method: Compositional matrix adjust.
 Identities = 362/865 (42%), Positives = 557/865 (65%), Gaps = 46/865 (5%)

Query  5    YRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIA  63
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKTMQRNWIGRSEGVEITFNVNDYDNT  242
            V RK + QW +KITAYA+ LL+DL+ +D WP+++K MQRNWIG+S G ++TF+V+D D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGCTYLAVAAGHPLAQ--KAAENNPELAAFIDECR-NTKVAEAEMATME  299
            +TV+TTRPDT+ G TY  +A+ H+L +   ++++   +A +  +   ++ +A +++A  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGVDTGFKAVHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPV  359
            K GV TG  A++P+ G E+PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L+I PV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  360  ILAADGSEPDLSQQALTEKGVLFNSGEFNGLDHEAAFNAIADKLTAMGVGERKVNYRLRD  419
            +        ++ + A+TE G+ +NS+ ++GLD  +A+  + + L A GVG+ +V YRLRD
Sbjct  362  L-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMVTLEDGTVMPTPDDQLPVILP--EDVVMDGIT-SPIKADPEWAKT  476
            W  SRQRYWG PIP++  EDGT  + P+ +LP++LP   D+   G   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  T-VNGMPALRETDTFDTFMESSWYYARYTCPQYKEGMLDSEAANYWLPVDIYIGGIEHAI  535
            T  +G+ + RET+T      SSWYY RY  P+  E + D E  + WLPVDIY+GG EHA+
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVER  595
            +HLLY RF HK++ D G+V + EP ++L+ QGM+L+ ++      + R  + + D +  R
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEKR  591

Query  596  DEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMT  655
            D  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D +
Sbjct  592  D--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  656  LEWQESGVEGANRFLKRVWKLVYEHTAKGDVAALNVDALTENQKALRRDVHKTIAKVTDD  715
            + W E G+EG+ +FL RV +L+   T+K        +   EN  AL +  + T+  VT++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLI---TTK--------EITEENSGALDKVYNETVKAVTEQ  695

Query  716  IGRRQTFNTAIAAIMELMNKLAKAPTDGEQDRALMQEALLAVVRMLNPFTPHICFTLWQE  775
            +++ + FNTAIA +M ++N        ++++  L  +   + V+++ PF+PH+   LWQ 
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  776  LKGEGD-IDNAPWPVADEKAMVEDSTLVVVQVNGKVRAKITVPVDATEEQVRERAGQEHL  834
            L + G+ I   PWP  DE  +VE+   +VVQ++GKV+AK+ V+ D + E+++E A  ++ 
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  835  VAKYLDGVTVRKVIYVPGKLLNLVV  859
            V   + G  + KVI VP KL+N+V+
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVI  832

1136) leuS in NC_020518


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  542 bits (2045),  Expect = 4e-155, Method: Compositional matrix adjust.
 Identities = 362/865 (42%), Positives = 557/865 (65%), Gaps = 46/865 (5%)

Query  5    YRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIA  63
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKTMQRNWIGRSEGVEITFNVNDYDNT  242
            V RK + QW +KITAYA+ LL+DL+ +D WP+++K MQRNWIG+S G ++TF+V+D D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGCTYLAVAAGHPLAQ--KAAENNPELAAFIDECR-NTKVAEAEMATME  299
            +TV+TTRPDT+ G TY  +A+ H+L +   ++++   +A +  +   ++ +A +++A  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGVDTGFKAVHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPV  359
            K GV TG  A++P+ G E+PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L+I PV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  360  ILAADGSEPDLSQQALTEKGVLFNSGEFNGLDHEAAFNAIADKLTAMGVGERKVNYRLRD  419
            +        ++ + A+TE G+ +NS+ ++GLD  +A+  + + L A GVG+ +V YRLRD
Sbjct  362  L-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMVTLEDGTVMPTPDDQLPVILP--EDVVMDGIT-SPIKADPEWAKT  476
            W  SRQRYWG PIP++  EDGT  + P+ +LP++LP   D+   G   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  T-VNGMPALRETDTFDTFMESSWYYARYTCPQYKEGMLDSEAANYWLPVDIYIGGIEHAI  535
            T  +G+ + RET+T      SSWYY RY  P+  E + D E  + WLPVDIY+GG EHA+
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVER  595
            +HLLY RF HK++ D G+V + EP ++L+ QGM+L+ ++      + R  + + D +  R
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEKR  591

Query  596  DEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMT  655
            D  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D +
Sbjct  592  D--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  656  LEWQESGVEGANRFLKRVWKLVYEHTAKGDVAALNVDALTENQKALRRDVHKTIAKVTDD  715
            + W E G+EG+ +FL RV +L+   T+K        +   EN  AL +  + T+  VT++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLI---TTK--------EITEENSGALDKVYNETVKAVTEQ  695

Query  716  IGRRQTFNTAIAAIMELMNKLAKAPTDGEQDRALMQEALLAVVRMLNPFTPHICFTLWQE  775
            +++ + FNTAIA +M ++N        ++++  L  +   + V+++ PF+PH+   LWQ 
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  776  LKGEGD-IDNAPWPVADEKAMVEDSTLVVVQVNGKVRAKITVPVDATEEQVRERAGQEHL  834
            L + G+ I   PWP  DE  +VE+   +VVQ++GKV+AK+ V+ D + E+++E A  ++ 
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  835  VAKYLDGVTVRKVIYVPGKLLNLVV  859
            V   + G  + KVI VP KL+N+V+
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVI  832

1137) leuS in NC_000913


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  542 bits (2045),  Expect = 4e-155, Method: Compositional matrix adjust.
 Identities = 362/865 (42%), Positives = 557/865 (65%), Gaps = 46/865 (5%)

Query  5    YRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIA  63
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKTMQRNWIGRSEGVEITFNVNDYDNT  242
            V RK + QW +KITAYA+ LL+DL+ +D WP+++K MQRNWIG+S G ++TF+V+D D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGCTYLAVAAGHPLAQ--KAAENNPELAAFIDECR-NTKVAEAEMATME  299
            +TV+TTRPDT+ G TY  +A+ H+L +   ++++   +A +  +   ++ +A +++A  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGVDTGFKAVHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPV  359
            K GV TG  A++P+ G E+PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L+I PV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  360  ILAADGSEPDLSQQALTEKGVLFNSGEFNGLDHEAAFNAIADKLTAMGVGERKVNYRLRD  419
            +        ++ + A+TE G+ +NS+ ++GLD  +A+  + + L A GVG+ +V YRLRD
Sbjct  362  L-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMVTLEDGTVMPTPDDQLPVILP--EDVVMDGIT-SPIKADPEWAKT  476
            W  SRQRYWG PIP++  EDGT  + P+ +LP++LP   D+   G   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  T-VNGMPALRETDTFDTFMESSWYYARYTCPQYKEGMLDSEAANYWLPVDIYIGGIEHAI  535
            T  +G+ + RET+T      SSWYY RY  P+  E + D E  + WLPVDIY+GG EHA+
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVER  595
            +HLLY RF HK++ D G+V + EP ++L+ QGM+L+ ++      + R  + + D +  R
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEKR  591

Query  596  DEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMT  655
            D  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D +
Sbjct  592  D--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  656  LEWQESGVEGANRFLKRVWKLVYEHTAKGDVAALNVDALTENQKALRRDVHKTIAKVTDD  715
            + W E G+EG+ +FL RV +L+   T+K        +   EN  AL +  + T+  VT++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLI---TTK--------EITEENSGALDKVYNETVKAVTEQ  695

Query  716  IGRRQTFNTAIAAIMELMNKLAKAPTDGEQDRALMQEALLAVVRMLNPFTPHICFTLWQE  775
            +++ + FNTAIA +M ++N        ++++  L  +   + V+++ PF+PH+   LWQ 
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  776  LKGEGD-IDNAPWPVADEKAMVEDSTLVVVQVNGKVRAKITVPVDATEEQVRERAGQEHL  834
            L + G+ I   PWP  DE  +VE+   +VVQ++GKV+AK+ V+ D + E+++E A  ++ 
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  835  VAKYLDGVTVRKVIYVPGKLLNLVV  859
            V   + G  + KVI VP KL+N+V+
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVI  832

1138) leuS in NC_007779


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  542 bits (2045),  Expect = 4e-155, Method: Compositional matrix adjust.
 Identities = 362/865 (42%), Positives = 557/865 (65%), Gaps = 46/865 (5%)

Query  5    YRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIA  63
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKTMQRNWIGRSEGVEITFNVNDYDNT  242
            V RK + QW +KITAYA+ LL+DL+ +D WP+++K MQRNWIG+S G ++TF+V+D D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGCTYLAVAAGHPLAQ--KAAENNPELAAFIDECR-NTKVAEAEMATME  299
            +TV+TTRPDT+ G TY  +A+ H+L +   ++++   +A +  +   ++ +A +++A  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGVDTGFKAVHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPV  359
            K GV TG  A++P+ G E+PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L+I PV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  360  ILAADGSEPDLSQQALTEKGVLFNSGEFNGLDHEAAFNAIADKLTAMGVGERKVNYRLRD  419
            +        ++ + A+TE G+ +NS+ ++GLD  +A+  + + L A GVG+ +V YRLRD
Sbjct  362  L-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMVTLEDGTVMPTPDDQLPVILP--EDVVMDGIT-SPIKADPEWAKT  476
            W  SRQRYWG PIP++  EDGT  + P+ +LP++LP   D+   G   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  T-VNGMPALRETDTFDTFMESSWYYARYTCPQYKEGMLDSEAANYWLPVDIYIGGIEHAI  535
            T  +G+ + RET+T      SSWYY RY  P+  E + D E  + WLPVDIY+GG EHA+
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVER  595
            +HLLY RF HK++ D G+V + EP ++L+ QGM+L+ ++      + R  + + D +  R
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEKR  591

Query  596  DEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMT  655
            D  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D +
Sbjct  592  D--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  656  LEWQESGVEGANRFLKRVWKLVYEHTAKGDVAALNVDALTENQKALRRDVHKTIAKVTDD  715
            + W E G+EG+ +FL RV +L+   T+K        +   EN  AL +  + T+  VT++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLI---TTK--------EITEENSGALDKVYNETVKAVTEQ  695

Query  716  IGRRQTFNTAIAAIMELMNKLAKAPTDGEQDRALMQEALLAVVRMLNPFTPHICFTLWQE  775
            +++ + FNTAIA +M ++N        ++++  L  +   + V+++ PF+PH+   LWQ 
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  776  LKGEGD-IDNAPWPVADEKAMVEDSTLVVVQVNGKVRAKITVPVDATEEQVRERAGQEHL  834
            L + G+ I   PWP  DE  +VE+   +VVQ++GKV+AK+ V+ D + E+++E A  ++ 
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  835  VAKYLDGVTVRKVIYVPGKLLNLVV  859
            V   + G  + KVI VP KL+N+V+
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVI  832

1139) leuS in NC_007946


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  542 bits (2045),  Expect = 4e-155, Method: Compositional matrix adjust.
 Identities = 361/865 (42%), Positives = 555/865 (65%), Gaps = 46/865 (5%)

Query  52   YRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIA  110
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  111  RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSR  170
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  171  ELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  229
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  230  VERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKTMQRNWIGRSEGVEITFNVKDYDNT  289
            V RK + QW +KITAYA+ LL+DL+ +D WP+++K MQRNWIG+S G ++TF+VKD D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  290  LTVYTTRPDTFMGCTYLAVAAGHPLAQ--KAAENNPELAAFIDECR-NTKVAEAEMATME  346
            +TV+TTRPDT+ G TY  +A+ H+L +   ++++   +A +  +   ++ +A +++A  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  347  KKGVDTGFKAVHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPV  406
            K GV TG  A++P+ G E+PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L+I PV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  407  ILAADGSEPDLSQQALTEKGVLFNSGEFNGLDHEAAFNAIADKLTEMGVGERKVNYRLRD  466
            +        ++ + A+TE G+ +NS+ ++GLD  +A+  + + L   GVG+ +V YRLRD
Sbjct  362  L-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  467  WGVSRQRYWGAPIPMVTLEDGTVMPTPDDQLPVILP--EDVVMDGIT-SPIKADPEWAKT  523
            W  SRQRYWG PIP++  EDGT  + P+ +LP++LP   D+   G   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  524  T-VNGMPALRETDTFDTFMESSWYYARYTCPEYKEGMLDSKAANYWLPVDIYIGGIEHAI  582
            T  +G+ + RET+T      SSWYY RY  P+  E + D    + WLPVDIY+GG EHA+
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  583  MHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVER  642
            +HLLY RF HK++ D G+V + EP ++L+ QGM+L+ +  Y +  G    + + D +  R
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS--YRDSRGA---LVATDKVEKR  591

Query  643  DEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMT  702
            D  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D +
Sbjct  592  D--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  703  LEWQESGVEGANRFLKRVWKLVYEHTAKGDVAALNVDALTEDQKALRRDVHKTIAKVTDD  762
            + W E G+EG+ +FL RV +L+   T+K        +   E+  AL +  + T+  VT++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLI---TTK--------EITEENSGALDKVYNETVKAVTEQ  695

Query  763  IGRRQTFNTAIAAIMELMNKLAKAPTDGEQDRALMQEALLAVVRMLNPFTPHICFTLWQE  822
            +++ + FNTAIA +M ++N        ++++  L  +   + V+++ PF+PH+   LWQ 
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  823  LKGEGD-IDNAPWPVADEKAMVEDSTLVVVQVNGKVRAKITVPVDATEEQVRERAGQEHL  881
            L + G+ I   PWP  DE  +VE+   +VVQ++GKV+AK+ V+ D + E+++E A  ++ 
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  882  VAKYLDGVTVRKVIYVPGKLLNLVV  906
            V   + G  + KVI VP KL+N+V+
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVI  832

1140) leuS in NC_014215


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  542 bits (2045),  Expect = 4e-155, Method: Compositional matrix adjust.
 Identities = 351/857 (41%), Positives = 544/857 (64%), Gaps = 66/857 (7%)

Query  20   YDAPAAEAKWQKYWAEHETFKASDAPDDKRQRRYVLDMFPYPSG-DLHMGHAEAYAMGDV  78
            YD  A E+KWQ +WA+++TFK+  + D  + + Y LDMFPYPSG +LH+GH+E+Y+  D+
Sbjct  4    YDHTAIEPKWQAFWADNHTFKT--GTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDI  61

Query  79   LARSWRMQGFNVMHPIGWDSFGLPAENAAIKNNEHPARWTYENIATQKKSFQRYGLSLDW  138
            L+R  R QG NV+HP+GWD+FGLPAE+ A+   ++PA  T ENIA  K+ ++  G+S DW
Sbjct  62   LSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDW  121

Query  139  SRELHTSDEEYYHWTQWLFIQFFKKGLAYQKDGYVNWCPKDQTVLANEQV-KEGRCERCG  197
             RE++T+D +YY WTQW+F +++ KGLAY+ +  VNW     T +ANE+V  +G  ER G
Sbjct  122  DREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGG  181

Query  198  TLVTKRELKQWYFRITEYAQRLLDDMAQLEGKWPERVLAMQRNWIGRSEGAWVKFHIDGR  257
              V ++ ++QW ++IT YA+RLL+D+ +++  WPE +  MQRNWIG+S GA V F + + 
Sbjct  182  YPVVRKPMRQWMLKITAYAERLLEDLEEVD--WPESIKDMQRNWIGKSTGANVTFKVKDT  239

Query  258  DEPVTVFTTRPDTLYGATFMVVAPDAALADEVVTDEHRAAFEAYREKTNHSTEIERQSTE  317
            D   TVFTTRPDTL+GAT+ V+AP+ AL D + T ++  A   Y+ +++  +++ R    
Sbjct  240  DKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA  299

Query  318  HVKTGVPLGVEATNPVNGEKIPVWAADYVLSEYGSGAVMAVPAHDQRDLDFALKYGLPVR  377
              KTGV  G  A NPVNG  +PVW ADYVL+ YG+GA+MAVPAHD+RD +FA ++ L + 
Sbjct  300  KEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDII  359

Query  378  QVIDTGEGDPAQTGVATAGDGAYMNSGPLDGLKDKESGKKTIVEQLQAQGTGEQTVTYRL  437
             V++ G+ + A    A + DG  +NS+ LDGL DK S+   +VE L+A+G G++ VTYRL
Sbjct  360  PVLEGGNVEEA----AFTEDGLHINSDFLDGL-DKASAIAKMVEWLEAEGVGNENVTYRL  414

Query  438  RDWLLSRQRFWGCPIPIIHCPNCGDVPVPDDQLPVKLPDLRGEALAPKGISPLAAATQWK  497
            RDWL+SRQR+WG PIPIIH  +    +VP+ +LP+ LP  ++   +  G SPLA  T+W 
Sbjct  415  RDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWL  474

Query  498  SVTCPVCGKPAERDTDTMDTFVDSSWYFFRYCSPHDDQGPFRAEDVARWAPVDQYIGGAE  557
             VT     K + R+T+TM    +SSWY++RY  PH+ +     E + +W PVD Y+GGAE
Sbjct  475  EVTREDGVK-GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAE  533

Query  558  HATMHLLYARFFTKVLKDLGMIDFVEPFTRLLNQGQVINQG-------------------  598
            HA +HLLYARF  KVL DLG++   EPF +L+NQG ++  +                   
Sbjct  534  HAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDG  593

Query  599  ---------------KAMSKSLGNGVNLGEQLDKYGVDAVRLTVVFAGPPDEDIDWADLS  643
                             MSKSL N VN ++ +++YG D++R+  +F GP D  I W++ +
Sbjct  594  SFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEG  653

Query  644  PKSSLRFLQRAHRLAGEVTSPLGADPASGDRPLRRATHKAISEITDLLAAGRFNVAIARI  703
              +S +FL+R  RL   +T+   ++  SG  +L +  + ++  +T+ +   +FN AIA++
Sbjct  654  LEGSRKFLDRVYRL---ITTKEITEENSG--ALDKVYNETVKAVTEQVDQMKFNTAIAQL  708

Query  704  MELVNATRKTVDGHNAPNSNAGSDDPAVREAVEFIAQALSLFAPYVSEEMWEVL-GHAPS  762
            M +VNA+ K              +D    +    + Q ++ FAP ++EE+W+ L + + S
Sbjct  709  MVFVNAANK--------------EDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGES  754

Query  763  IADSSWPTADPALLAAEEVTMVVQVQGKVRAKLSVSPQITEQQAIEAAMADSNVQRALNG  822
            I+  +WP+ D + L  ++V +VVQ++GKV+AKL V+ +++ ++  E A+A+ +VQ  + G
Sbjct  755  ISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAG  814

Query  823  RPVVKTITKLPRMVSLV  839
            + ++K I+   ++V++V
Sbjct  815  KDIIKVIAVPNKLVNIV  831

1141) leuS in NC_020506


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  542 bits (2045),  Expect = 5e-155, Method: Compositional matrix adjust.
 Identities = 362/745 (49%), Positives = 511/745 (69%), Gaps = 71/745 (9%)

Query  220  LVYRSNSTVNWCPGLGTVLANEEVTADGRSERGNFPVFRKNLSQWMMRITAYSdrliddl  279
            L Y ++  VNW   LGT +ANEEV +DG SERG +PV RK + QWM++ITAY++RL++DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  280  dlldwpdKVKSMQRNWIGRSRGAEVDFTAEG--ETITVFTTRPDTLFGATYMVLAPEHEL  337
            + +DWP+ +K MQRNWIG+S GA+V F   +    +TVFTTRPDTLFGATY VLAPEH L
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  338  VDTLTARAGAYENTDARWTNGQATPAEAVAAYRAGIAAKSDLERQE-NKEKTGVFLGVYA  396
            VD++T+                +  AEAVA Y+   + KSDL R +  KEKTGV  G YA
Sbjct  268  VDAITT----------------SDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYA  311

Query  397  TNPVNGEQIPVFIADYVLTGYGTGAIMAVPAHDERDYEFATVLGLPIKEVVAGGNIAEAA  456
             NPVNG ++PV IADYVL++YGTGAIMAVPAHDERD EFA  + L I  V+ GGN+ EAA
Sbjct  312  INPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEAA  371

Query  457  FTESGAAVNSANDQGLDLNGLAKEDAIAKTIEWLESKGPGRGTIQYKLRDWLFARQRYWG  516
            FTE G  +NS       L+GL K  AIAK +EWLE+ G G   + Y+LRDWLF+RQRYWG
Sbjct  372  FTEDGLHINSDF-----LDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWG  426

Query  517  EPFPVVYDEDGLAHSLPESMLPVELPEVEDYKPVSFDPNDADSEPSPPLAKAREWVEVEL  576
            EP+P++  EDG + ++PES LP+ LP   D +P         +   +PLA+  +W+EV  
Sbjct  427  EPIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTDWLEVTR  478

Query  577  DLGDGLKKYTRDTNVMPQWAGSSWYQLRYIDPSNDEMFCDIENERYWTGPRPDVHGPNDP  636
            +  DG+K   R+TN MPQWAGSSWY LRYIDP N E + D E  + W             
Sbjct  479  E--DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLP-----------  524

Query  637  GGVDLYVGGVEHAVLHLLYSRFWHKVLFDLGYVSSKEPYRRLYNQGYIQAYAYTDSRGVY  696
              VD+YVGG EHAVLHLLY+RFWHKVL+DLG V++KEP+++L+NQG I + +Y DSRG  
Sbjct  525  --VDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGAL  582

Query  697  VPAEEVEEKDGKFFY--QGEEVNQEYGKMGKSLKNAVAPDDICANYGADTLRVYEMFMGP  754
            V+++ VE +DG FF    GEE++Q  +KM+KSLKN V PDD+  +YGADTLRVYEMFMGP
Sbjct  583  VATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGP  642

Query  755  LDTSRPWATKDVVGAQRFLQRLWRLVVDENTGEVLVNDAALSDEDNKQLHRTIAGVTDDY  814
            LD+S +W+  ++ G+++FL+R+ RL+   +  E   N +AL    +K  + T+ +VT++ 
Sbjct  643  LDASIAWSEEGLEGSRKFLDRVYRLITTKEITE--ENSGAL----DKVYNETVKAVTEQV  696

Query  815  TNLRVNTVVSKLIEYVNYLTK------TYPKAVPEAAVVPLAIMVSPVAPHIAEELWKQL  868
             +++ NT +++L+ +VN   K       Y+K+  +        +++P APH++EELW+ L
Sbjct  697  DQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQ--------LIAPFAPHLGEELWQAL  748

Query  869  -GHDDTITYQPFPTFDEKWLKDDEIELPVQVNGKVRGRVTVAADATQEQIMEIVLNDEKI  927
             + +++I+Y P P++DE  L ++++E+ VQ++GKV++++ VA D ++E++ E+ L +EK+
Sbjct  749  TASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKV  808

Query  928  QEHIAGKNLFKQIVVPGRMVNLVVK  952
            Q +IAGK+++K I VP ++VN+V+K
Sbjct  809  QAEIAGKDIIKVIAVPNKLVNIVIK  833


 Score =  139 bits (509),  Expect = 1e-33, Method: Compositional matrix adjust.
 Identities = 77/149 (52%), Positives = 103/149 (70%), Gaps = 11/149 (7%)

Query  23   IEGEWQNFWKEHGTFNAPNPKGDLAPADGHALPDDKLFVQDMFPYPSGAGLHVGHPLGYI  82
            IE  WQ FW ++ TF++           G   +  K++  DMFPYPSGAGLHVGHP GY 
Sbjct  9    IEPKWQAFWADNHTFKT-----------GTDASKPKFYALDMFPYPSGAGLHVGHPEGYT  57

Query  83   ATDVFARYNRMLGKNVLHTLGYDAFGLPAEQYAIQTGTHPRTTTMANIENMKRQLGALGL  142
            ATD+++R++R  G NVLH +G DAFGLPAEQYA++TG +P   T  NI N KRQ+ ALG+
Sbjct  58   ATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGF  117

Query  143  GHDPRRSVASTDPEFYKWTQWIFLQIFNS  171
            + D  R V +TDP++YKWTQWIF ++++ 
Sbjct  118  SYDWDREVNTTDPNYYKWTQWIFTKLYEK  146

1142) leuS in NC_011295


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  542 bits (2044),  Expect = 5e-155, Method: Compositional matrix adjust.
 Identities = 372/859 (44%), Positives = 548/859 (64%), Gaps = 68/859 (7%)

Query  18   YDFKKAEERWSKYWQERGLFKANGTLGTKPKQYVLEMFPYPSGK-LHMGHVRNYSLGDVV  76
            YD    E +W  +W +   FK+ GT ++KPK Y L+MFPYPSG  LH+GH   Y+  D++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKT-GTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDIL  62

Query  77   ARYNRMRGFDVLHPMGWDAFGLPAENAAIERGIHPENWTLSNIGYMREQMKKLGFSYDWD  136
            +R++R +G +VLHPMGWDAFGLPAE+ A++ G +P + T  NI+  + Q++ LGFSYDWD
Sbjct  63   SRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWD  122

Query  137  REVATCLPDYYKWTQWLFLKLYENGLAYKKRAKVNWCPHCKTVLANEQVI-DGKCWRCHS  195
            REV T  P+YYKWTQW+F KLYE+GLAY     VNW  +  T +ANE+V+ DG   R   
Sbjct  123  REVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGY  182

Query  196  PIEKREIEQWFFKITAYAEdllndldnldWPEHVKAQQRNWIGRSEGALVKFAIEGTDKV  255
            P+ ++ + QW +KITAYAE LL+DL+++DWPE +K  QRNWIG+S GA V F + +TDK 
Sbjct  183  PVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  256  IEIFTTRLDTIYGATFMVLAPEHPLAMELVQGTALKELYDEYLKRISLKSEIDRLSTEKE  315
            + +FTTR DT++GAT+ VLAPEH+L ++ +  +   E   +Y ++ SLKS++ R    KE
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHAL-VDAITTSDQAEAVADYKRQASLKSDLARTDLAKE  301

Query  316  KEGFFLGKYAVNPFNGERIPIYAGDYVLTEYGTGAIMAVPAHDERDYAFAVKYNIPIRPV  375
            K G   G YA+NP NG  +P+  +DYVL+ YGTGAIMAVPAHDERD  FA ++N+ I PV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  376  VVPKDGEEIKNGEVFTEYGVLVNSGPYTGKTSEEAQKLMAEYLEEHNLGQKSVTYRLRDW  435
            +   +G ++ ++  FTE G+ +NS+   G     A   M E LE + +G+ +VTYRLRDW
Sbjct  362  L---EGGNVEEA-AFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDW  417

Query  436  LVSRQRYWGAPIPVVYCEHCGTVPVPEDQLPVILPREVDYLPGDLV-SPLATDEEFVHTT  494
            L SRQRYWG PIP++  E+  + +VPE +LP++LP   D  P++   SPLA   + ++ T
Sbjct  418  LFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT  477

Query  495  CPKCGGPARRETDTMDTFVDSSWYYLRYVDPHNEQAPFDKELAQYWMPVDIYIGGVEHAV  554
                G  +RRET+TM    +SSWYYLRY+DPHN +   D EL + W+PVDIY+GG EHAV
Sbjct  478  RED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  555  LHLLYSRFITKALKDMGYVTISEPFSKLFTQGMV--------------------------  588
            LHLLY+RF  K L D+G V   EPF KLF QGM+                          
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFF  596

Query  589  --------TLGGSAMSKSKGNIVDPDDILRDYGADAARMYTLFVAPPEKDFEWSQQGLEG  640
                      + + MSKS  N+V+PDD++ +YGAD+ R+Y +F++P +  + WS++GLEG
Sbjct  597  HVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEG  656

Query  641  IVRFIRRIWNFYCKYADEVKEAVAAPMGKLFEGMSEYDEKALRAVNRLVYRVTEDIEDNY  700
              +F+ R+  +    + E+ E  +++++K+++        +++AV   V        D+ 
Sbjct  657  SRKFLDRVYRLIT--TKEITEENSGALDKVYNE-------TVKAVTEQV--------DQM  699

Query  701  RFNTAIAAMMEFLNEVTDYDEKVSSAVMKTLLETFAKVLAPFVPFLAEELWAML-GNAPS  759
            +FNTAIA +M F+N     ++K+ S   K     F +++APF P L+EELW  L +++ S
Sbjct  700  KFNTAIAQLMVFVNAANK-EDKLFSDYAK----GFVQLIAPFAPHLGEELWQALTASGES  754

Query  760  VHEQSWPQWDESMLQENTVEVAVQINGKFRGTVVVRNGASEEEVREAVMSSGNFSKYLSK  819
            +   +WP  DES L EN VE+ VQI+GK ++ +VV ++ S EE++E  +++ +    ++ 
Sbjct  755  ISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIA-  813

Query  820  EGGYKKCFYVPNKIINFIV  838
              +  K + VPNK++N+++
Sbjct  814  GKDIIKVIAVPNKLVNIVI  832

1143) leuS in NC_012489


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  542 bits (2044),  Expect = 5e-155, Method: Compositional matrix adjust.
 Identities = 360/840 (43%), Positives = 541/840 (65%), Gaps = 49/840 (5%)

Query  10   YDPRSIEPKWQTRWTERATNRAKLDTPERPFYALMMFPYPSAEGLHVGNLFAFTGSDISA  69
            YD  +IEPKWQ+ W++  T ++  D++   FYAL MFPYPS+ GLHVG+  ++T++DI +
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  70   RFHRLIGHDVFQPLGFDAFGIHSENYALKVGAHPMELTPKNVGNFTRQLERAGFMIDWNQ  129
            RF R  GH+V++P+G DAFG+ +E+YA+  G +P E+T+ N++NF RQ++  GF  DW++
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  130  KVDTSRADYYKWTQWVFLQLHKQGLAYKKAAAVNWCPTDKTVLANEQV-EGGLCERCGTA  188
             V+T+ ++YYKWTQW+F +L  +GLAY    +VNW     T +ANE+V  +G  ER G +
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  189  VEQRFLEQWFFRISEYAPRLLSNLDWLDWSPVTKQAQRNWIGKSEGAQLTFAVSGRSERI  248
            V ++ + QW ++I+ YA RLL +L+ +DW+   K+ QRNWIGKS GA++TF V +    +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  249  TVFTTRADTIFGATYLVLAPEHPLVASITTDAQRSDVAAYQERAT-KQDLISRKSSKDKT  307
            TVFTTR+DT+FGATY VLAPEH+LV +ITT  Q   VA Y+ +A+ K DL     +K+KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  308  GVFTGAYAVNPATGQNIPIWIADYVLMEYGTGAIMAVPGHDERDFEFAQVFDLPVVRVVa  367
            GV TG+YA+NP  G+++P+WIADYVL  YGTGAIMAVP+HDERD EFA+ F+L ++ V+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL-  362

Query  368  aadqqadtalgdaaFTDDDDACRLVNSGPFDGLAVRDAKREVTAWLADGGHGTAVTNYRL  427
                  +  + +AAFT+D+     +NS+ +DGL    A   +  WL   G G     YRL
Sbjct  363  -----EGGNVEEAAFTEDG---LHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRL  414

Query  428  HDWCISRQRYWGPPIPIIYCEDCGAVPVPESQLPVELPFIPDFKPDDSGISPLARHEEWY  487
            +DW +SRQRYWG PIPII  ED  + +VPES+LP+ LP   D++P ++G SPLA   +W 
Sbjct  415  RDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWL  474

Query  488  RVPCPTCGKNARRETDVSDTFLDSAWYFLRYPSATRDDVPFDAARTKTWLPVNSYIGGNE  547
             V     G ++RRET+      +S+WY+LRY  +   +   D    K WLPV+ Y+GG E
Sbjct  475  EVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAE  533

Query  548  HAVLHLLYSRFITMVLKDAGHIDFEEPFTRFRAHGMII-------------------REG  588
            HAVLHLLY+RF   VL D G +   EPF ++  +GMI+                   R+G
Sbjct  534  HAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDG  593

Query  589  ---------------AKMSKSKGNVINPDQYMEEWGADAFRMYLMFLGPYEEGGDFRDQG  633
                           AKMSKS  NV+NPD+ +E+ GAD++R+Y MF+GP + +    ++G
Sbjct  594  SFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEG  653

Query  634  ISGVRRFLDRLWASVRDAVRDGSPDPDVIRKLHRTIKKVGEDSANLGYNTAIAAMMEYMN  693
            + G R+FLDR+   +            + +  + T+K V E+  ++ +NTAIA +M ++N
Sbjct  654  LEGSRKFLDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVN  713

Query  694  AVRRGERVAHRAEVEPLVQLVAPYAPHLAEECWETLGHQGSVFD-AGWPSFdaaqlvdde  752
            A  + +++        +VQL+AP+APHL+EE W++L   G  +    WPS+D ++LV+++
Sbjct  714  AANKEDKL-FSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVEND  772

Query  753  vdlvvqvNGKVRGKIRVPADIGSDEAMVRAVSDETIAKFVVGTP-KKVIFVPKRLLNIVV  811
            V++VVQ++GKV++K+ V+ D++ +E    A+++E +   + G    KVI VP++L+NIV+
Sbjct  773  VEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

1144) leuS in NC_010468


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  542 bits (2044),  Expect = 5e-155, Method: Compositional matrix adjust.
 Identities = 360/865 (42%), Positives = 557/865 (65%), Gaps = 46/865 (5%)

Query  5    YRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIA  63
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKTMQRNWIGRSEGVEITFNVNDYDNT  242
            V RK + QW +KITAYA+ LL+DL+ +D WP+++K MQRNWIG+S G ++TF+V+D D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGCTYLAVAAGHPLAQ--KAAENNPELAAFIDECR-NTKVAEAEMATME  299
            +TV+TTRPDT+ G TY  +A+ H+L +   ++++   +A +  +   ++ +A +++A  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGVDTGFKAVHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPV  359
            K GV TG  A++P+ G E+PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L+I PV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  360  ILAADGSEPDLSQQALTEKGVLFNSGEFNGLDHEAAFNAIADKLTAMGVGERKVNYRLRD  419
            +        ++ + A+TE G+ +NS+ ++GLD  +A+  + + L A GVG+ +V YRLRD
Sbjct  362  L-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMVTLEDGTVMPTPDDQLPVILP--EDVVMDGIT-SPIKADPEWAKT  476
            W  SRQRYWG PIP++  EDGT  + P+ +LP++LP   D+   G   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  T-VNGMPALRETDTFDTFMESSWYYARYTCPQYKEGMLDSEAANYWLPVDIYIGGIEHAI  535
            T  +G+ + RET+T      SSWYY RY  P+  E + D E  + WLPVDIY+GG EHA+
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVER  595
            +HLLY RF HK++ D G+V + EP ++L+ QGM+L+ ++      + R  + + D +  R
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEKR  591

Query  596  DEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMT  655
            D  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D +
Sbjct  592  D--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  656  LEWQESGVEGANRFLKRIWKLVYEHTAKGDVAALNVDALTEDQKALRRDVHKTIAKVTDD  715
            + W E G+EG+ +FL R+ +L+   T+K        +   E+  AL +  + T+  VT++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLI---TTK--------EITEENSGALDKVYNETVKAVTEQ  695

Query  716  IGRRQTFNTAIAAIMELMNKLAKAPTDGEQDRALMQEALLAVVRMLNPFTPHICFTLWQE  775
            +++ + FNTAIA +M ++N        ++++  L  +   + V+++ PF+PH+   LWQ 
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  776  LKGEGD-IDNAPWPVADEKAMVEDSTLVVVQVNGKVRAKITVPVDATEEQVRERAGQEHL  834
            L + G+ I   PWP  DE  +VE+   +VVQ++GKV+AK+ V+ D + E+++E A  ++ 
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  835  VAKYLDGVTVRKVIYVPGKLLNLVV  859
            V   + G  + KVI VP KL+N+V+
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVI  832

1145) leuS in NC_011415


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  542 bits (2045),  Expect = 5e-155, Method: Compositional matrix adjust.
 Identities = 361/865 (42%), Positives = 557/865 (65%), Gaps = 46/865 (5%)

Query  5    YRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIA  63
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKTMQRNWIGRSEGVEITFNVNDYDNT  242
            V RK + QW +KITAYA+ LL+DL+ +D WP+++K MQRNWIG+S G ++TF+V+D D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGCTYLAVAAGHPLAQ--KAAENNPELAAFIDECR-NTKVAEAEMATME  299
            +TV+TTRPDT+ G TY  +A+ H+L +   ++++   +A +  +   ++ +A +++A  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGVDTGFKAVHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPV  359
            K GV TG  A++P+ G E+PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L+I PV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  360  ILAADGSEPDLSQQALTEKGVLFNSGEFNGLDHEAAFNAIADKLTAMGVGERKVNYRLRD  419
            +        ++ + A+TE G+ +NS+ ++GLD  +A+  + + L A GVG+ +V YRLRD
Sbjct  362  L-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMVTLEDGTVMPTPDDQLPVILP--EDVVMDGIT-SPIKADPEWAKT  476
            W  SRQRYWG PIP++  EDGT  + P+ +LP++LP   D+   G   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  T-VNGMPALRETDTFDTFMESSWYYARYTCPQYKEGMLDSEAANYWLPVDIYIGGIEHAI  535
            T  +G+ + RET+T      SSWYY RY  P+  E + D E  + WLPVDIY+GG EHA+
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVER  595
            +HLLY RF HK++ D G+V + EP ++L+ QGM+L+ ++      + R  + + D +  R
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEKR  591

Query  596  DEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMT  655
            D  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D +
Sbjct  592  D--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  656  LEWQESGVEGANRFLKRVWKLVYEHTAKGDVAALNVDALTEDQKALRRDVHKTIAKVTDD  715
            + W E G+EG+ +FL RV +L+   T+K        +   E+  AL +  + T+  VT++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLI---TTK--------EITEENSGALDKVYNETVKAVTEQ  695

Query  716  IGRRQTFNTAIAAIMELMNKLAKAPTDGEQDRALMQEALLAVVRMLNPFTPHICFTLWQE  775
            +++ + FNTAIA +M ++N        ++++  L  +   + V+++ PF+PH+   LWQ 
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  776  LKGEGD-IDNAPWPVADEKAMVEDSTLVVVQVNGKVRAKITVPVDATEEQVRERAGQEHL  834
            L + G+ I   PWP  DE  +VE+   +VVQ++GKV+AK+ V+ D + E+++E A  ++ 
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  835  VAKYLDGVTVRKVIYVPGKLLNLVV  859
            V   + G  + KVI VP KL+N+V+
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVI  832

1146) leuS in NC_007606


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  542 bits (2045),  Expect = 5e-155, Method: Compositional matrix adjust.
 Identities = 361/865 (42%), Positives = 557/865 (65%), Gaps = 46/865 (5%)

Query  5    YRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIA  63
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKTMQRNWIGRSEGVEITFNVNDYDNT  242
            V RK + QW +KITAYA+ LL+DL+ +D WP+++K MQRNWIG+S G ++TF+V+D D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGCTYLAVAAGHPLAQ--KAAENNPELAAFIDECR-NTKVAEAEMATME  299
            +TV+TTRPDT+ G TY  +A+ H+L +   ++++   +A +  +   ++ +A +++A  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGVDTGFKAVHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPV  359
            K GV TG  A++P+ G E+PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L+I PV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  360  ILAADGSEPDLSQQALTEKGVLFNSGEFNGLDHEAAFNAIADKLTAMGVGERKVNYRLRD  419
            +        ++ + A+TE G+ +NS+ ++GLD  +A+  + + L A GVG+ +V YRLRD
Sbjct  362  L-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMVTLEDGTVMPTPDDQLPVILP--EDVVMDGIT-SPIKADPEWAKT  476
            W  SRQRYWG PIP++  EDGT  + P+ +LP++LP   D+   G   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  TI-NGMPALRETDTFDTFMESSWYYARYTCPQYKEGMLDSEAANYWLPVDIYIGGIEHAI  535
            T  +G+ + RET+T      SSWYY RY  P+  E + D E  + WLPVDIY+GG EHA+
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVER  595
            +HLLY RF HK++ D G+V + EP ++L+ QGM+L+ ++      + R  + + D +  R
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEKR  591

Query  596  DEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMT  655
            D  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D +
Sbjct  592  D--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  656  LEWQESGVEGANRFLKRVWKLVYEHTAKGDVAALNVDALTEDQKALRRDVHKTIAKVTDD  715
            + W E G+EG+ +FL RV +L+   T+K        +   E+  AL +  + T+  VT++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLI---TTK--------EITEENSGALDKVYNETVKAVTEQ  695

Query  716  IGRRQTFNTAIAAIMELMNKLAKAPTDGEQDRALMQEALLAVVRMLNPFTPHICFTLWQE  775
            +++ + FNTAIA +M ++N        ++++  L  +   + V+++ PF+PH+   LWQ 
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  776  LKGEGD-IDNAPWPVADEKAMVEDSTLVVVQVNGKVRAKITVPVDATEEQVRERAGQEHL  834
            L + G+ I   PWP  DE  +VE+   +VVQ++GKV+AK+ V+ D + E+++E A  ++ 
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  835  VAKYLDGVTVRKVIYVPGKLLNLVV  859
            V   + G  + KVI VP KL+N+V+
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVI  832

1147) leuS in NC_012913


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  542 bits (2044),  Expect = 6e-155, Method: Compositional matrix adjust.
 Identities = 356/868 (42%), Positives = 564/868 (65%), Gaps = 50/868 (5%)

Query  5    YRPDLLEPEVQKFWQDNKTFKAVQDNNKEKYYCLSMFPYPSGR-LHMGHVRNYTIGDVVS  63
            Y    +EP  Q FW DN TFK+  D +K K+Y L MFPYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMKGKNVLQPFGWDAFGLPAEGAAVKNNTAPAKWTYENIAYMKKQLQILGFGFDWDR  123
            R++R +G NVL+P GWDAFGLPAE  A+     PA  T ENIA  K+Q++ LGF++DWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EIATCKPEYYKWEQWFFTELYKKGLVYKKTSTVNWCPNDETVLANEQV-HEGCCWRCDTP  182
            E+ T  P+YYKW QW+FT LY KGL Y     VNW  +  T +ANE+V  +G   R + P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VEQKEIPQWFIKITDYAEQLLNCLDDLPQWPDQVKTMQRNWIGRSEGVEITFDIKDTNEK  242
            V +K + QW +KIT YAE+LL+ L+++ +WP+ +K MQRNWIG+S G ++TF +KDT+  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LAVYTTRPDTFYGVSYv--avaaahplatlaaQNNPELAEFIQEAK-NTKVAEADIATME  299
            ++V+TTRPDT++G +Y   A   A   A  ++++   +A++ ++A  ++ +A +D+A  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGMPTGLYAIHPLTGEQVPVWVANFVLMHYGTGAVMAVPAHDQRDFEFAQKYHLPIKQV  359
            K G+ TG YAI+P+ G ++PVW+A++VL  YGTGA+MAVPAHD+RD EFA++++L I  V
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  360  IEPINGEAIDLTKQAFTEHGKLVHSGEFDGLAFDAAFNGIANKLESMGKGKRQVNYRLRD  419
            +     E+ ++   AFTE+G  ++S+ +DGL   +A+  + + LE+ G G+ +V YRLRD
Sbjct  362  L-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMLTLENGDVVPVPMEDLPIILP--EDVVMNGV-NSPIKADPEWAKT  476
            W  SRQRYWG PIP++  E+G   +VP  +LP++LP   D+  +G  +SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  TYL-GKPASKETDTFDTFMESSWYYARYTCPQYQQGMLNSEEANYWLPVDQYIGGIEHAT  535
            T   G  + +ET+T      SSWYY RY  P+  + + + E  + WLPVD Y+GG EHA 
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLLYFRFFHKLLRDAGLVNSDEPADKLLCQGMVLADAFYYTSPTNERIWVSPTKVTLER  595
            +HLLY RF HK+L D G+V + EP +KL+ QGM+L+ ++      + R     + V+ ++
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSR----GALVATDK  587

Query  596  DEK--GRIVKAVDDEGHELVHAGMTKMSKSKNNGIDPQEMVEKYGADTVRLFMMFASPAE  653
             EK  G +     + G+EL +A  +KMSKS +N ++P+++VE+YGADT+R++ MF +P +
Sbjct  588  VEKRDGSFFHV--ETGEELEQAP-AKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLD  644

Query  654  MTLEWQESGVEGAKRFLARVWNLVFEYNKNPTKTAVNPTALSASQKALRRDVHKTIAKVS  713
             ++ W E G+EG+++FL RV      Y    TK   +  +      AL +  + T+  V+
Sbjct  645  ASIAWSEEGLEGSRKFLDRV------YRLITTKEITEENS-----GALDKVYNETVKAVT  693

Query  714  DDIGRRQTFNTAIAAVMELMNKLTRAPLDDEQDRAIMAEALSAVVRMLYPITPHICFRLW  773
            +++++ + FNTAIA +M ++N         +++  + ++   + V+++ P++PH+   LW
Sbjct  694  EQVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELW  745

Query  774  QEL-GNQDAIDFAPWVEADEQAMVDDEKLIVVQVNGKVRGKVTVAADADEDTVKTMAFAD  832
            Q L ++ ++I + PW   DE  +V+++  IVVQ++GKV++K+ VA D   + ++ +A+A+
Sbjct  746  QALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALAN  805

Query  833  ENVKRFLDGMQVVKVIYVAGKLLNVVVK  860
            E+V+  + G +++KVI V+ KL+N+V+K
Sbjct  806  EKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

1148) leuS in NC_017641


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  542 bits (2044),  Expect = 6e-155, Method: Compositional matrix adjust.
 Identities = 362/865 (42%), Positives = 558/865 (65%), Gaps = 46/865 (5%)

Query  5    YRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIA  63
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKTMQRNWIGRSEGVEITFNVNDYDNT  242
            V RK + QW +KITAYA+ LL+DL+ +D WP+++K MQRNWIG+S G ++TF+V+D D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGCTYLAVAAGHPLAQ--KAAENNPELAAFIDECR-NTKVAEAEMATME  299
            +TV+TTRPDT+ G TY  +A+ H+L +   ++++   +A +  +   ++ +A +++A  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGVDTGFKAVHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPV  359
            K GV TG  A++P+ G E+PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L+I PV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  360  ILAADGSEPDLSQQALTEKGVLFNSGEFNGLDHEAAFNAIADKLTAMGVGERKVNYRLRD  419
            +        ++ + A+TE G+ +NS+ ++GLD  +A+  + + L A GVG+ +V YRLRD
Sbjct  362  L-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMVTLEDGTVMPTPDDQLPVILP--EDVVMDGI-NSPIKADPEWAKT  476
            W  SRQRYWG PIP++  EDGT  + P+ +LP++LP   D+   G  +SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  T-VNGMPALRETDTFDTFMESSWYYARYTCPEYKEGMLDSEAANYWLPVDIYIGGIEHAI  535
            T  +G+ + RET+T      SSWYY RY  P+  E + D E  + WLPVDIY+GG EHA+
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVER  595
            +HLLY RF HK++ D G+V + EP ++L+ QGM+L+ ++      + R  + + D +  R
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEKR  591

Query  596  DEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMT  655
            D  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D +
Sbjct  592  D--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  656  LEWQESGVEGANRFLKRVWKLVYEHTAKGDVAALNVDALTENQKALRRDVHKTIAKVTDD  715
            + W E G+EG+ +FL RV +L+   T+K        +   EN  AL +  + T+  VT++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLI---TTK--------EITEENSGALDKVYNETVKAVTEQ  695

Query  716  IGRRQTFNTAIAAIMELMNKLAKAPTDGEQDRALMQEALLAVVRMLNPFTPHICFTLWQE  775
            +++ + FNTAIA +M ++N        ++++  L  +   + V+++ PF+PH+   LWQ 
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  776  LKGEGD-IDNAPWPVADEKAMVEDSTLVVVQVNGKVRAKITVPVDATEEQVRERAGQEHL  834
            L + G+ I   PWP  DE  +VE+   +VVQ++GKV+AK+ V+ D + E+++E A  ++ 
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  835  VAKYLDGVTVRKVIYVPGKLLNLVV  859
            V   + G  + KVI VP KL+N+V+
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVI  832

1149) Csal_2344 in NC_007963


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  541 bits (2040),  Expect = 1e-154, Method: Compositional matrix adjust.
 Identities = 361/867 (42%), Positives = 564/867 (66%), Gaps = 52/867 (5%)

Query  5    YTPHAIESAAQTFWDKNQCFKAVEDATREKFYCLSMFPYPSGK-LHMGHVRNYTIGDVVS  63
            Y   AIE+  Q+FW  N+ FK+  DA++ KFY L MFPYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RFQRMQGKNVLQPMGWDAFGMPAENAAIKNRVPPGAWTYDNIDAMRRQLKALGFAYDWNR  123
            RF+R QG NVL+PMGWDAFG+PAE+ A+     P+  T +NI   +RQ++ALGF+YDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EFATCDVDYYRWEQWFFTKLVEKGLVYKKMSTVNWDPVDQTVLANEQVI-EGRGWRSGAL  182
            E  T D +YY+W QW+FTKL EKGL Y     VNW     T +ANE+V+ +G + R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPLWFLKITDYADELLADLDKVDWPEQVKTMQRNWIGKSTGVELSFAVADSSEQL  242
            V RK +  W LKIT YA+ LL DL+ VDWPE +K MQRNWIGKSTG +++F V D+  ++
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  243  EVYTTRPDTLYGVTYVAVAAGHPL--ARQAAQDNPALGDFL-EECQQGGNSEAELATMEK  299
             V+TTRPDTL+G TY  +A+ H+L  A  ++++  A++D+  +   +++ + ++LA  EK
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KEK  302

Query  300  KGMDTGHKAIHPLTGREVPIFVANFVLMEYGTGAVMAVPAHDQRDWEFATKYGIPIEPVI  359
             G+ TG  AI+P+ G+E+P+ +A++VL  YGTGA+MAVPAHD+RDWEFA ++ + I PV+
Sbjct  303  TGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL  362

Query  360  ADAEGNTPDLSQGAHTEHGKLINSGEFDGLEFDAAFDAIAARLEANGQGTVKTNFRLRDW  419
             ++     ++ ++A TE+G  INS+ +DGL+  +A+  +  +LEA+G G  +  +RLRDW
Sbjct  363  EGG-----NVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDW  417

Query  420  GVARQRYWGAPIPVKYGPEGQTVPLTDDELPVALPMEVEVDASG---SPLKKMPAFYDLG  476
              +RQRYWG PIP+    +G + ++ + ELP+ LP+  ++ +SG   SPL ++    ++ 
Sbjct  418  LFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT  477

Query  477  -----EGWTRETDTFDTFMESSWYYARFASADNMEAMLDER-ADYWLPVDLYIGGIEHAI  530
                  G  RET+T      SSWYY R+  ++N E + DE     WLPVD+Y+GG EHA+
Sbjct  478  REDGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  531  LHLLYARFFHKLMRDFGLVASDEPFQRLLTQGMVIAETFYRANDDGSKDWFNPADVDVQR  590
            LHLLYARF HK++ D+G+V++ EPFQ+L+ QGM+++ + YR + ++         V  ++
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS-YRDSRGAL--------VATDK  587

Query  591  DDKGRPVSAILREDGQPVEMGGIEKMSKSKNNGVDPQAMIDRFGADTVRLFMMFAAPPEQ  650
             +K R  S +  E G+ +E +   KMSKS +N V+P+ +++++GADT+R++ MF +P + 
Sbjct  588  VEK-RDGSFFHVETGEELEQAP-AKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  651  SLEWSDSGVEGAHRFLKRLWKLVADHLDAGTPaaldadalnddQKTLRRKTHETIAKASD  710
            S+ WS+ G+EG+++FL R+ +L++             +  +++  +L +  +ET+   ++
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLITTK-----------EITEENSGALDKVYNETVKAVTE  694

Query  711  DIGRRTTFNTAIAAVMELVNAIGRFEDTSPQGLAVTREALEACVLVLAPIVPHACHALWD  770
            ++++   FNTAIA +M +VNA  + ED       +  +   + V ++AP+ PH  + LW+
Sbjct  695  QVDQM-KFNTAIAQLMVFVNAANK-EDK------LFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  771  ALGHDTPVID-AAWPQADEAAMVKDSVELAVQVNGKLRARLDVPaaadkaaieaqaleae  829
            AL      I   +WP  DE+ +V + VE+ VQ++GK++A+L V+    +  ++  AL  E
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  830  NVRRHTEGKTIRKVIVVPGKLVNIVAN  856
            +V+ +  GK I KVI VP KLVNIV +
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVIK  833

1150) leuS in NC_017390


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  541 bits (2040),  Expect = 1e-154, Method: Compositional matrix adjust.
 Identities = 358/866 (42%), Positives = 550/866 (64%), Gaps = 48/866 (5%)

Query  5    YRPEEIESHVQQHWDDKQTFKVTEEEGKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIS  63
            Y    IE+  Q  W D++TFK   + +K K+Y L M+PYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYANIDYMKNQLKLLGFGYDWNR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T  NI   K Q++ LGF+YDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCQPEYYRWEQWFFTKLYEKGLVYKKTSAVNWCPHDMTVLANEQVI-DGCCWRCDSK  182
            E+ T +P+YY+W QW+FTKLYEKGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFVKITDYADELLNDLDKLESWPEQVKTMQRNWIGRSEGVEIEFNVIDSEEK  242
            V RK + QW +KIT YA+ LL+DL+ ++ WPE +K MQRNWIG+S G ++ F+V D++  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LSVYTTRPDTFMGVTYLAVAAGHplaaqaamnnpalaDFIAECRNTKVAEADMA----TM  298
            ++V+TTRPDT+ G TY  +A+ H  A   A+  +  A+ +A+ +      +D+A    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEH--ALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  299  EKKGMATGLFAEHPLTGEKVPVWVANFVLMEYGTGAVMAVPGHDQRDWEFASKYSLPIKA  358
            EK G+ TG +A +P+ G  +PVW+A++VL  YGTGA+MAVP+HD+RDWEFA +++L I +
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VILAADGSAPDLSASAMTEKGTLFNSGEFDGLSHEAGFDAIAARLADRGVGERKVNYRLR  418
            V+      + ++  +A TE G  +NS+ +DGL   +++  +  +L   GVG+ +V YRLR
Sbjct  361  VL-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  419  DWGVSRQRYWGAPIPMVTLEDGTVMPTPEDQLPVVLP--EDVVMDGIT-SPIKADAAWAE  475
            DW  SRQRYWG PIP++  EDGT  + PE +LP+VLP   D+   G   SP+   + W E
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  476  TT-VNGQPALRETDTFDTFMESSWYYARYTCPDYDKGMLNPAAANYWLPVDQYVGGIEHA  534
             T  +G  + RET+T      SSWYY RY  P+    + +    + WLPVD YVGG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  535  IMHLLYFRFFHKLLRDAGLVNSDEPAKRLLCQGMVLADAFYFTGSNGERNWVSPTDVSVE  594
            ++HLLY RF HK+L D G+V + EP ++L+ QGM+L+ ++      + R     + V+ +
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRG----ALVATD  586

Query  595  RDEKGRITKATDNDGHELVYAGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPAEM  654
            + EK   +    + G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P + 
Sbjct  587  KVEKRDGSFFHVETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  655  TLEWQESGVEGANRFLKRVWRLAFEHTEKGTATALDVDALNDDQKALRRDLHKTISKVSD  714
            ++ W E G+EG+ +FL RV RL    T K  +        +++  AL +  + T+  V++
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLI---TTKEIT--------EENSGALDKVYNETVKAVTE  694

Query  715  DIGRRQTFNTAIAAIMELMNKLARAPQESTQDRALMQEALLAVVRMLNPFTPHVSFVLWQ  774
            ++++ + FNTAIA +M ++N        + ++  L  +   + V+++ PF+PH++  LWQ
Sbjct  695  QVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  775  ALGGAGE-IDNAPWPQADEAAMVEDSLLVVVQVNGKVRGKITVAADATQEQVQARAAQEH  833
            AL ++GE I   PWP  DE+ +VE+ + +VVQ++GKV++K+ VA D ++E++Q  A  ++
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  834  LVAKYLDGVTIRKVIYVPGKLLNLVV  859
             V   + G  I KVI VP KL+N+V+
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVI  832

1151) leuS in NC_012214


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  541 bits (2040),  Expect = 1e-154, Method: Compositional matrix adjust.
 Identities = 358/866 (42%), Positives = 550/866 (64%), Gaps = 48/866 (5%)

Query  5    YRPEEIESHVQQHWDDKQTFKVTEEEGKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIS  63
            Y    IE+  Q  W D++TFK   + +K K+Y L M+PYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYANIDYMKNQLKLLGFGYDWNR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T  NI   K Q++ LGF+YDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCQPEYYRWEQWFFTKLYEKGLVYKKTSAVNWCPHDMTVLANEQVI-DGCCWRCDSK  182
            E+ T +P+YY+W QW+FTKLYEKGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFVKITDYADELLNDLDKLESWPEQVKTMQRNWIGRSEGVEIEFNVIDSEEK  242
            V RK + QW +KIT YA+ LL+DL+ ++ WPE +K MQRNWIG+S G ++ F+V D++  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LSVYTTRPDTFMGVTYLAVAAGHplaaqaamnnpalaDFIAECRNTKVAEADMA----TM  298
            ++V+TTRPDT+ G TY  +A+ H  A   A+  +  A+ +A+ +      +D+A    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEH--ALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  299  EKKGMATGLFAEHPLTGEKVPVWVANFVLMEYGTGAVMAVPGHDQRDWEFASKYSLPIKA  358
            EK G+ TG +A +P+ G  +PVW+A++VL  YGTGA+MAVP+HD+RDWEFA +++L I +
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VILAADGSAPDLSASAMTEKGTLFNSGEFDGLSHEAGFDAIAARLADRGVGERKVNYRLR  418
            V+      + ++  +A TE G  +NS+ +DGL   +++  +  +L   GVG+ +V YRLR
Sbjct  361  VL-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  419  DWGVSRQRYWGAPIPMVTLEDGTVMPTPEDQLPVVLP--EDVVMDGIT-SPIKADAAWAE  475
            DW  SRQRYWG PIP++  EDGT  + PE +LP+VLP   D+   G   SP+   + W E
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  476  TT-VNGQPALRETDTFDTFMESSWYYARYTCPDYDKGMLNPAAANYWLPVDQYVGGIEHA  534
             T  +G  + RET+T      SSWYY RY  P+    + +    + WLPVD YVGG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  535  IMHLLYFRFFHKLLRDAGLVNSDEPAKRLLCQGMVLADAFYFTGSNGERNWVSPTDVSVE  594
            ++HLLY RF HK+L D G+V + EP ++L+ QGM+L+ ++      + R     + V+ +
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRG----ALVATD  586

Query  595  RDEKGRITKATDNDGHELVYAGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPAEM  654
            + EK   +    + G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P + 
Sbjct  587  KVEKRDGSFFHVETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  655  TLEWQESGVEGANRFLKRVWRLAFEHTEKGTATALDVDALNDDQKALRRDLHKTISKVSD  714
            ++ W E G+EG+ +FL RV RL    T K  +        +++  AL +  + T+  V++
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLI---TTKEIT--------EENSGALDKVYNETVKAVTE  694

Query  715  DIGRRQTFNTAIAAIMELMNKLARAPQESTQDRALMQEALLAVVRMLNPFTPHVSFVLWQ  774
            ++++ + FNTAIA +M ++N        + ++  L  +   + V+++ PF+PH++  LWQ
Sbjct  695  QVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  775  ALGGAGE-IDNAPWPQADEAAMVEDSLLVVVQVNGKVRGKITVAADATQEQVQARAAQEH  833
            AL ++GE I   PWP  DE+ +VE+ + +VVQ++GKV++K+ VA D ++E++Q  A  ++
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  834  LVAKYLDGVTIRKVIYVPGKLLNLVV  859
             V   + G  I KVI VP KL+N+V+
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVI  832

1152) leuS in NC_017628


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  541 bits (2040),  Expect = 1e-154, Method: Compositional matrix adjust.
 Identities = 360/865 (42%), Positives = 555/865 (65%), Gaps = 46/865 (5%)

Query  5    YRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIA  63
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKTMQRNWIGRSEGVEITFNVKDYDNT  242
            V RK + QW +KITAYA+ LL+DL+ +D WP+++K MQRNWIG+S G ++TF+VKD D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGCTYLAVAAGHPLAQ--KAAENNPELAAFIDECR-NTKVAEAEMATME  299
            +TV+TTRPDT+ G TY  +A+ H+L +   ++++   +A +  +   ++ +A +++A  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGVDTGFKAVHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPV  359
            K GV TG  A++P+ G E+PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L+I PV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  360  ILAADGSEPDLSQQALTEKGVLFNSGEFNGLDHEAAFNAIADKLTEMGVGERKVNYRLRD  419
            +        ++ + A+TE G+ +NS+ ++GLD  +A+  + + L   GVG+ +V YRLRD
Sbjct  362  L-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMVTLEDGTVMPTPDDQLPVILP--EDVVMDGIT-SPIKADPEWAKT  476
            W  SRQRYWG PIP++  EDGT  + P+ +LP++LP   D+   G   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  T-VNGMPALRETDTFDTFMESSWYYARYTCPEYKEGMLDSKAANYWLPVDIYIGGIEHAI  535
            T  +G+ + RET+T      SSWYY RY  P+  E + D    + WLPVDIY+GG EHA+
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVER  595
            +HLLY RF HK++ D G+V + EP ++L+ QGM+L+ ++      + R  + + D +  R
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEKR  591

Query  596  DEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMT  655
            D  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D +
Sbjct  592  D--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  656  LEWQESGVEGANRFLKRVWKLVYEHTAKGDVAALNVDALTEDQKALRRDVHKTIAKVTDD  715
            + W E G+EG+ +FL RV +L+   T+K        +   E+  AL +  + T+  VT++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLI---TTK--------EITEENSGALDKVYNETVKAVTEQ  695

Query  716  IGRRQTFNTAIAAIMELMNKLAKAPTDGEQDRALMQEALLAVVRMLNPFTPHICFTLWQE  775
            +++ + FNTAIA +M ++N        ++++  L  +   + V+++ PF+PH+   LWQ 
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  776  LKGEGD-IDNAPWPVADEKAMVEDSTLVVVQVNGKVRAKITVPVDATEEQVRERAGQEHL  834
            L + G+ I   PWP  DE  +VE+   +VVQ++GKV+AK+ V+ D + E+++E A  ++ 
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  835  VAKYLDGVTVRKVIYVPGKLLNLVV  859
            V   + G  + KVI VP KL+N+V+
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVI  832

1153) leuS in NC_011601


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  541 bits (2040),  Expect = 1e-154, Method: Compositional matrix adjust.
 Identities = 360/865 (42%), Positives = 556/865 (65%), Gaps = 46/865 (5%)

Query  5    YRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIA  63
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKTMQRNWIGRSEGVEITFNVNDYDNT  242
            V RK + QW +KITAYA+ LL+DL+ +D WP+++K MQRNWIG+S G ++TF+V+D D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGCTYLAVAAGHPLAQ--KAAENNPELAAFIDECR-NTKVAEAEMATME  299
            +TV+TTRPDT+ G TY  +A+ H+L +   ++++   +A +  +   ++ +A +++A  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGVDTGFKAVHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPV  359
            K GV TG  A++P+ G E+PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L+I PV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  360  ILAADGSEPDLSQQALTEKGVLFNSGEFNGLDHEAAFNAIADKLTAMGVGERKVNYRLRD  419
            +        ++ + A+TE G+ +NS+ ++GLD  +A+  + + L A GVG+ +V YRLRD
Sbjct  362  L-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMVTLEDGTVMPTPDDQLPVILP--EDVVMDGIT-SPIKADPEWAKT  476
            W  SRQRYWG PIP++  EDGT  + P+ +LP++LP   D+   G   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  T-VNGMPALRETDTFDTFMESSWYYARYTCPQYKEGMLDSKAANYWLPVDIYIGGIEHAI  535
            T  +G+ + RET+T      SSWYY RY  P+  E + D    + WLPVDIY+GG EHA+
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVER  595
            +HLLY RF HK++ D G+V + EP ++L+ QGM+L+ ++      + R  + + D +  R
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEKR  591

Query  596  DEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMT  655
            D  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D +
Sbjct  592  D--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  656  LEWQESGVEGANRFLKRVWKLVYEHTAKGDVAALNVDALTEDQKALRRDVHKTIAKVTDD  715
            + W E G+EG+ +FL RV +L+   T+K        +   E+  AL +  + T+  VT++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLI---TTK--------EITEENSGALDKVYNETVKAVTEQ  695

Query  716  IGRRQTFNTAIAAIMELMNKLAKAPTDGEQDRALMQEALLAVVRMLNPFTPHICFTLWQE  775
            +++ + FNTAIA +M ++N        ++++  L  +   + V+++ PF+PH+   LWQ 
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  776  LKGEGD-IDNAPWPVADEKAMVEDSTLVVVQVNGKVRAKITVPVDATEEQVRERAGQEHL  834
            L + G+ I   PWP  DE  +VE+   +VVQ++GKV+AK+ V+ D + E+++E A  ++ 
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  835  VAKYLDGVTVRKVIYVPGKLLNLVV  859
            V   + G  + KVI VP KL+N+V+
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVI  832

1154) leuS in NC_022370


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  541 bits (2040),  Expect = 1e-154, Method: Compositional matrix adjust.
 Identities = 360/865 (42%), Positives = 555/865 (65%), Gaps = 46/865 (5%)

Query  5    YRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIA  63
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKTMQRNWIGRSEGVEITFNVKDYDNT  242
            V RK + QW +KITAYA+ LL+DL+ +D WP+++K MQRNWIG+S G ++TF+VKD D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGCTYLAVAAGHPLAQ--KAAENNPELAAFIDECR-NTKVAEAEMATME  299
            +TV+TTRPDT+ G TY  +A+ H+L +   ++++   +A +  +   ++ +A +++A  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGVDTGFKAVHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPV  359
            K GV TG  A++P+ G E+PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L+I PV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  360  ILAADGSEPDLSQQALTEKGVLFNSGEFNGLDHEAAFNAIADKLTEMGVGERKVNYRLRD  419
            +        ++ + A+TE G+ +NS+ ++GLD  +A+  + + L   GVG+ +V YRLRD
Sbjct  362  L-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMVTLEDGTVMPTPDDQLPVILP--EDVVMDGIT-SPIKADPEWAKT  476
            W  SRQRYWG PIP++  EDGT  + P+ +LP++LP   D+   G   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  T-VNGMPALRETDTFDTFMESSWYYARYTCPEYKEGMLDSKAANYWLPVDIYIGGIEHAI  535
            T  +G+ + RET+T      SSWYY RY  P+  E + D    + WLPVDIY+GG EHA+
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVER  595
            +HLLY RF HK++ D G+V + EP ++L+ QGM+L+ ++      + R  + + D +  R
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEKR  591

Query  596  DEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMT  655
            D  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D +
Sbjct  592  D--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  656  LEWQESGVEGANRFLKRVWKLVYEHTAKGDVAALNVDALTEDQKALRRDVHKTIAKVTDD  715
            + W E G+EG+ +FL RV +L+   T+K        +   E+  AL +  + T+  VT++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLI---TTK--------EITEENSGALDKVYNETVKAVTEQ  695

Query  716  IGRRQTFNTAIAAIMELMNKLAKAPTDGEQDRALMQEALLAVVRMLNPFTPHICFTLWQE  775
            +++ + FNTAIA +M ++N        ++++  L  +   + V+++ PF+PH+   LWQ 
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  776  LKGEGD-IDNAPWPVADEKAMVEDSTLVVVQVNGKVRAKITVPVDATEEQVRERAGQEHL  834
            L + G+ I   PWP  DE  +VE+   +VVQ++GKV+AK+ V+ D + E+++E A  ++ 
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  835  VAKYLDGVTVRKVIYVPGKLLNLVV  859
            V   + G  + KVI VP KL+N+V+
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVI  832

1155) leuS in NC_011742


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  541 bits (2040),  Expect = 1e-154, Method: Compositional matrix adjust.
 Identities = 360/865 (42%), Positives = 555/865 (65%), Gaps = 46/865 (5%)

Query  5    YRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIA  63
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKTMQRNWIGRSEGVEITFNVKDYDNT  242
            V RK + QW +KITAYA+ LL+DL+ +D WP+++K MQRNWIG+S G ++TF+VKD D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGCTYLAVAAGHPLAQ--KAAENNPELAAFIDECR-NTKVAEAEMATME  299
            +TV+TTRPDT+ G TY  +A+ H+L +   ++++   +A +  +   ++ +A +++A  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGVDTGFKAVHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPV  359
            K GV TG  A++P+ G E+PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L+I PV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  360  ILAADGSEPDLSQQALTEKGVLFNSGEFNGLDHEAAFNAIADKLTEMGVGERKVNYRLRD  419
            +        ++ + A+TE G+ +NS+ ++GLD  +A+  + + L   GVG+ +V YRLRD
Sbjct  362  L-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMVTLEDGTVMPTPDDQLPVILP--EDVVMDGIT-SPIKADPEWAKT  476
            W  SRQRYWG PIP++  EDGT  + P+ +LP++LP   D+   G   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  T-VNGMPALRETDTFDTFMESSWYYARYTCPEYKEGMLDSKAANYWLPVDIYIGGIEHAI  535
            T  +G+ + RET+T      SSWYY RY  P+  E + D    + WLPVDIY+GG EHA+
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVER  595
            +HLLY RF HK++ D G+V + EP ++L+ QGM+L+ ++      + R  + + D +  R
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEKR  591

Query  596  DEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMT  655
            D  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D +
Sbjct  592  D--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  656  LEWQESGVEGANRFLKRVWKLVYEHTAKGDVAALNVDALTEDQKALRRDVHKTIAKVTDD  715
            + W E G+EG+ +FL RV +L+   T+K        +   E+  AL +  + T+  VT++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLI---TTK--------EITEENSGALDKVYNETVKAVTEQ  695

Query  716  IGRRQTFNTAIAAIMELMNKLAKAPTDGEQDRALMQEALLAVVRMLNPFTPHICFTLWQE  775
            +++ + FNTAIA +M ++N        ++++  L  +   + V+++ PF+PH+   LWQ 
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  776  LKGEGD-IDNAPWPVADEKAMVEDSTLVVVQVNGKVRAKITVPVDATEEQVRERAGQEHL  834
            L + G+ I   PWP  DE  +VE+   +VVQ++GKV+AK+ V+ D + E+++E A  ++ 
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  835  VAKYLDGVTVRKVIYVPGKLLNLVV  859
            V   + G  + KVI VP KL+N+V+
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVI  832

1156) leuS in NC_010658


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  541 bits (2040),  Expect = 1e-154, Method: Compositional matrix adjust.
 Identities = 359/865 (42%), Positives = 557/865 (65%), Gaps = 46/865 (5%)

Query  5    YRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIA  63
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKSMQRNWIGRSEGVEITFNVNDYDNT  242
            V RK + QW +KITAYA+ LL+DL+ +D WP+++K MQRNWIG+S G ++TF+V+D D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGCTYLAVAAGHPLAQ--KAAENNPELAAFIDECR-NTKVAEAEMATME  299
            +TV+TTRPDT+ G TY  +A+ H+L +   ++++   +A +  +   ++ +A +++A  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGVDTGFKAVHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPV  359
            K GV TG  A++P+ G E+PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L+I PV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  360  ILAADGSEPDLSQQALTEKGVLFNSGEFNGLDHEAAFNAIADKLTAMGVGERKVNYRLRD  419
            +        ++ + A+TE G+ +NS+ ++GLD  +A+  + + L A GVG+ +V YRLRD
Sbjct  362  L-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMVTLEDGTVMPTPDDQLPVILP--EDVVMDGIT-SPIKADPEWAKT  476
            W  SRQRYWG PIP++  EDGT  + P+ +LP++LP   D+   G   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  T-VNGMPALRETDTFDTFMESSWYYARYTCPEYKEGMLDSEAANYWLPVDIYIGGIEHAI  535
            T  +G+ + RET+T      SSWYY RY  P+  E + D E  + WLPVDIY+GG EHA+
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVER  595
            +HLLY RF HK++ D G+V + EP ++L+ QGM+L+ ++      + R  + + D +  R
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEKR  591

Query  596  DEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMT  655
            D  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D +
Sbjct  592  D--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  656  LEWQESGVEGANRFLKRVWKLVYEHTAKGDVAALNVDGLTEDQKALRRDVHKTIAKVTDD  715
            + W E G+EG+ +FL RV +L+    +  +++        E+  AL +  + T+  VT++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLI----TTKEITE-------ENSGALDKVYNETVKAVTEQ  695

Query  716  IGRRQTFNTAIAAIMELMNKLAKAPTDGEQDRALMQEALLAVVRMLNPFTPHICFTLWQE  775
            +++ + FNTAIA +M ++N        ++++  L  +   + V+++ PF+PH+   LWQ 
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  776  LKGEGD-IDNAPWPVADEKAMVEDSTLVVVQVNGKVRAKITVPVDATEEQVRERAGQEHL  834
            L + G+ I   PWP  DE  +VE+   +VVQ++GKV+AK+ V+ D + E+++E A  ++ 
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  835  VAKYLDGVTVRKVIYVPGKLLNLVV  859
            V   + G  + KVI VP KL+N+V+
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVI  832

1157) leuS in NC_004757


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  541 bits (2040),  Expect = 1e-154, Method: Compositional matrix adjust.
 Identities = 353/876 (41%), Positives = 553/876 (64%), Gaps = 58/876 (6%)

Query  5    YHPQEIERQARQSWQETNIFNVTEIPDRPKYYCLSMFPYPSGK-LHMGHVRNYTIGDVLS  63
            Y+   IE + +  W + + F+    + +PK+Y L MFPYPSG  LH+GH   YT  D+LS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYRRMQGYNVMQPMGWDAFGLPAENAAIQKGVPPAKWTYDNIAYMRSQLQSLGFAIDWQR  123
            R++R QG NV++PMGWDAFGLPAE+ A++ G  PA  T +NIA  + Q+++LGF+ DW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCDPQYYRWNQWLFLRMLEKGIAYQKTQVVNWDPVDQTVLANEQVI-DGCGWRTGAV  182
            E+ T DP+YY+W QW+F ++ EKG+AY+    VNW     T +ANE+V+ DG + R G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VEKREIPGYYLAITRYADELLADLEKLPGWPERVKTMQANWIGKSFGVDITFPPDTASGM  242
            V ++ +    L IT YA+ LL DLE + +WPE +K MQ NWIGKS G ++TF      + 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTF---KVKDT  239

Query  243  PQALKVFTTRADTLMGVTYVAVAAEHPVALHAAHNQPDLVAFIESCRQGATMEAELA---  299
             + + VFTTR+DTL G TY  +A+EH  AL  A   +D    +   ++ A++ ++LA   
Sbjct  240  DKDFTVFTTRPDTLFGATYAVLAPEH--ALVDAITTSDQAEAVADYKRQASLKSDLARTD  297

Query  300  -VQEKKGMATGLYVLHPLTGERLPVWVANYVLMSYGEGAVMAVPAHDERDFDFARQHSLP  358
              +EK G+ TG Y ++P+ G  +PVW+A+YVL SYG GA+MAVPAHDERD +FA+Q +L 
Sbjct  298  LAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLD  357

Query  359  IKPVIRPENGELSVPLVQAFTEYGVTFNSDRFSDLTSPEAIDAIAVELGQKALGEKRVRY  418
            I PV+  E G++  +   AFTE G+ +NSD + +L  + AI  +   L   ++G+  V Y
Sbjct  358  IIPVL--EGGNVEEA---AFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTY  412

Query  419  RLRDWGISRQRYWGCPIPLIHCDSCGVVPVADDQLPVVLP--EDLVPDGSGN-PLAKTPS  475
            RLRDW +SRQRYWG PIP+IH +     +V++ +LP+VLP   D+ P G+G+ PLA+   
Sbjct  413  RLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTD  472

Query  476  FYECTCPRCGRQARRETDTMDTFVDSSWYFIRYACPDQSAAMTDQR-ANYWLPVDQYIGG  534
              E T    G ++RRET+TM    +SSWY++RY  P+++  ++D+   + WLPVD Y+GG
Sbjct  473  WLEVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGG  531

Query  535  IEHAILHLLYSRFWSKVMRDLGLVSFDEPFANLLTQGMVLNEIFFRKTSSGRIQYFNPAE  594
             EHA+LHLLY+RFW KV+ DLG+V+  EPF +L+ QGM+L   +  + S G +       
Sbjct  532  AEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY--RDSRGAL-------  582

Query  595  VDVQHDGEGKRVGAVLQADNQPVESGGIGTMSKSKNNGIDPQEIIEQYGADTARLFMMFA  654
              V  D   KR G+ ++ +       + + MSKS +N ++P++++EQYGADT R++ MF 
Sbjct  583  --VATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFM  640

Query  655  SPPTQTLEWSDAGVEGAFRFLKRLWRQVYLHRQLDGEAAATTTLVPHQEYPADLRDLRCQ  714
            +P   ++ WS+ G+EG+ +FL R+ R +   +++  E +++               L   
Sbjct  641  GPLDASIAWSEEGLEGSRKFLDRVYRLI-TTKEITEENSGA---------------LDKV  684

Query  715  LHQTIVKVTDDLERRHTFNTAIAAIMELMNELSDVQGTHPAARQLMQEALENIVLLLSPI  774
             ++T+  VT+++++   FNTAIA +M ++N  +  +       +L  +    +V L++P+
Sbjct  685  YNETVKAVTEQVDQMK-FNTAIAQLMVFVNAANKED-------KLFSDYAKGFVQLIAPF  736

Query  775  VPHICHVLWRELRPGTELLD-QPWPQADDQALIQDEVEIVVQINGKLRGQIRIAREADRA  833
             PH+ + LW+ L ++ E +   PWP  D+  L++++VEIVVQI+GK+++++ +A++  R 
Sbjct  737  APHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSRE  796

Query  834  AVERTALQDEHIQKSIAYRPVKRVIVVPGKLINIVV  869
             ++  AL +E +Q  IA + + +VI VP KL+NIV+
Sbjct  797  ELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

1158) Q91_1664 in NC_018697


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  541 bits (2043),  Expect = 5e-155, Method: Compositional matrix adjust.
 Identities = 345/856 (41%), Positives = 544/856 (64%), Gaps = 71/856 (8%)

Query  5    YQPSLIEKSVQEKWQLTGAFEVTEDTTKEKYYCLSMFPYPSGR-LHMGHVRNYTIGDVVS  63
            Y+ + IE   Q  W    +F    D++K K+Y L MFPYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMKGKNVMQPMGWDAFGLPAENAAMKHGVHPGGWTSDNIDYMRTQLKQLGFGYDWKR  123
            R++R +G NV++PMGWDAFGLPAE+ AM  G +P+  T++NI   + Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVATCNDDYYRWEQWFFTRLLEKDLVYKKTAPLNWCPDCNTVLANEQVI-DGCCWRCDNE  182
            EV T + +YY+W QW+FT+L EK+L Y    P+NW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VEKREISQWFMRITNYADELLSSLKELEGWPEQVRTMQQNWIGRSEGVELSFDIEGSDST  242
            V ++ + QW ++IT YA+ LL  L E++ WPE ++ MQ+NWIG+S G +++F + ++D  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LPVYTTRPDTLMGVTYVAVAAEHPL--ALQAAENNTDIAEFLDQCKtmetseaametmeK  300
            + V+TTRPDTL G TY  +A+EH+L  A+ ++++   +A++  Q         +  + EK
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEK  302

Query  301  KGIDSGLKAIHPLTGETVPIWIANFVLMHYGTGAVMSVPAHDQRDFEFANKYGLAIKQVI  360
             G+ +G  AI+P+ G  +P+WIA++VL  YGTGA+M+VPAHD+RD EFA+++ L I  V+
Sbjct  303  TGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL  362

Query  361  ATDNPGEIDLTKQAYTGKGTLLNSAEFDGLDFQQAFDAIAESLSAKGKGKKTVNFRLRDW  420
              +N  E      A+T  G  +NS  +DGLD   A+  + E L A G G+  V +RLRDW
Sbjct  363  EGGNVEE-----AAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDW  417

Query  421  GISRQRYWGTPVPVIYCDDCGTVPVPDEQLPVILP--KDVSLEGVG-SPLARHEEFINTS  477
             +SRQRYWG P+P+I  +D  + +VP+ +LP++LP  KD+   G G SPLA   + ++ +
Sbjct  418  LFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT  477

Query  478  CPTCGQQAKRETDTFDTFMESSWYFARYCCADNDQAMLDER-ANYWLPVDQYIGGIEHAI  536
                G +++RET+T      SSWY+ RY  ++N + + DE   + WLPVD Y+GG EHA+
Sbjct  478  RED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  537  LHLLYSRFYTKLLRDLGLVSCDEPFKNLLTQGMVL-------------------KDGT--  575
            LHLLY+RF  K+L DLG+V+  EPF++L+ QGM+L                   +DG+  
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFF  596

Query  576  -------------KMSKSKGNTVDPQGLIEKYGADTVRLFTMFAAPPEQSLEWSDSAVEG  622
                         KMSKS  N V+P++++E+YGADT+R++ MF +P + S+ WS+ ++EG
Sbjct  597  HVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEG  656

Query  623  SFRFIRRLWRQVKEHVDGGLISGYTVDQLSSEDK-VLRRQVHETLNKVNDDYGRRLTFNT  681
            S +F+ R+ R +            T  +++ E+   L +  +ET++ V ++   ++ FNT
Sbjct  657  SRKFLDRVYRLI------------TTKEITEENSGALDKVYNETVKAVTEQ-VDQMKFNT  703

Query  682  AIAANMELLNSVSKFKAETDASRALLQEALESIVLMLSPIIPHVCDQMWQALGHQDPLID  741
            AIA  M ++N+ +K          L+ +   ++V +++P+ PH+ +++WQAL   +  I 
Sbjct  704  AIAQLMVFVNAANK-------EDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESIS  756

Query  742  -VTWPEFDETALVLDEVQMVVQVNGKLRAKLMVAADASKESIEKLALSEDNVNKFIDGKP  800
             V WP +DE+ LV ++V++VVQ++GK++AKL+VA D S+E ++ +AL++++V+  I GK 
Sbjct  757  YVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKD  816

Query  801  VRKVIIVPKRLVNIVI  816
            + KVI VP++LVNIVI
Sbjct  817  IIKVIAVPNKLVNIVI  832

1159) leuS in NC_012971


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  541 bits (2043),  Expect = 6e-155, Method: Compositional matrix adjust.
 Identities = 361/865 (42%), Positives = 558/865 (65%), Gaps = 46/865 (5%)

Query  5    YRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIA  63
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKTMQRNWIGRSEGVEITFNVNDYDNT  242
            V RK + QW +KITAYA+ LL+DL+ +D WP+++K MQRNWIG+S G ++TF+V+D D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGCTYLAVAAGHPLAQ--KAAENNPELAAFIDECR-NTKVAEAEMATME  299
            +TV+TTRPDT+ G TY  +A+ H+L +   ++++   +A +  +   ++ +A +++A  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGVDTGFKAVHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPV  359
            K GV TG  A++P+ G E+PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L+I PV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  360  ILAADGSEPDLSQQALTEKGVLFNSGEFNGLDHEAAFNAIADKLTAMGVGERKVNYRLRD  419
            +        ++ + A+TE G+ +NS+ ++GLD  +A+  + + L A GVG+ +V YRLRD
Sbjct  362  L-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMVTLEDGTVMPTPDDQLPVILP--EDVVMDGI-NSPIKADPEWAKT  476
            W  SRQRYWG PIP++  EDGT  + P+ +LP++LP   D+   G  +SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  T-VNGMPALRETDTFDTFMESSWYYARYTCPEYKEGMLDSEAANYWLPVDIYIGGIEHAI  535
            T  +G+ + RET+T      SSWYY RY  P+  E + D E  + WLPVDIY+GG EHA+
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVER  595
            +HLLY RF HK++ D G+V + EP ++L+ QGM+L+ ++      + R  + + D +  R
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEKR  591

Query  596  DEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMT  655
            D  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D +
Sbjct  592  D--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  656  LEWQESGVEGANRFLKRVWKLVYEHTAKGDVAALNVDALTEDQKALRRDVHKTIAKVTDD  715
            + W E G+EG+ +FL RV +L+   T+K        +   E+  AL +  + T+  VT++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLI---TTK--------EITEENSGALDKVYNETVKAVTEQ  695

Query  716  IGRRQTFNTAIAAIMELMNKLAKAPTDGEQDRALMQEALLAVVRMLNPFTPHICFTLWQE  775
            +++ + FNTAIA +M ++N        ++++  L  +   + V+++ PF+PH+   LWQ 
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  776  LKGEGD-IDNAPWPVADEKAMVEDSTLVVVQVNGKVRAKITVPVDATEEQVRERAGQEHL  834
            L + G+ I   PWP  DE  +VE+   +VVQ++GKV+AK+ V+ D + E+++E A  ++ 
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  835  VAKYLDGVTVRKVIYVPGKLLNLVV  859
            V   + G  + KVI VP KL+N+V+
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVI  832

1160) leuS in NC_012892


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  541 bits (2043),  Expect = 6e-155, Method: Compositional matrix adjust.
 Identities = 361/865 (42%), Positives = 558/865 (65%), Gaps = 46/865 (5%)

Query  5    YRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIA  63
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKTMQRNWIGRSEGVEITFNVNDYDNT  242
            V RK + QW +KITAYA+ LL+DL+ +D WP+++K MQRNWIG+S G ++TF+V+D D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGCTYLAVAAGHPLAQ--KAAENNPELAAFIDECR-NTKVAEAEMATME  299
            +TV+TTRPDT+ G TY  +A+ H+L +   ++++   +A +  +   ++ +A +++A  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGVDTGFKAVHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPV  359
            K GV TG  A++P+ G E+PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L+I PV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  360  ILAADGSEPDLSQQALTEKGVLFNSGEFNGLDHEAAFNAIADKLTAMGVGERKVNYRLRD  419
            +        ++ + A+TE G+ +NS+ ++GLD  +A+  + + L A GVG+ +V YRLRD
Sbjct  362  L-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMVTLEDGTVMPTPDDQLPVILP--EDVVMDGI-NSPIKADPEWAKT  476
            W  SRQRYWG PIP++  EDGT  + P+ +LP++LP   D+   G  +SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  T-VNGMPALRETDTFDTFMESSWYYARYTCPEYKEGMLDSEAANYWLPVDIYIGGIEHAI  535
            T  +G+ + RET+T      SSWYY RY  P+  E + D E  + WLPVDIY+GG EHA+
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVER  595
            +HLLY RF HK++ D G+V + EP ++L+ QGM+L+ ++      + R  + + D +  R
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEKR  591

Query  596  DEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMT  655
            D  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D +
Sbjct  592  D--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  656  LEWQESGVEGANRFLKRVWKLVYEHTAKGDVAALNVDALTEDQKALRRDVHKTIAKVTDD  715
            + W E G+EG+ +FL RV +L+   T+K        +   E+  AL +  + T+  VT++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLI---TTK--------EITEENSGALDKVYNETVKAVTEQ  695

Query  716  IGRRQTFNTAIAAIMELMNKLAKAPTDGEQDRALMQEALLAVVRMLNPFTPHICFTLWQE  775
            +++ + FNTAIA +M ++N        ++++  L  +   + V+++ PF+PH+   LWQ 
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  776  LKGEGD-IDNAPWPVADEKAMVEDSTLVVVQVNGKVRAKITVPVDATEEQVRERAGQEHL  834
            L + G+ I   PWP  DE  +VE+   +VVQ++GKV+AK+ V+ D + E+++E A  ++ 
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  835  VAKYLDGVTVRKVIYVPGKLLNLVV  859
            V   + G  + KVI VP KL+N+V+
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVI  832

1161) leuS in NC_012947


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  541 bits (2043),  Expect = 6e-155, Method: Compositional matrix adjust.
 Identities = 361/865 (42%), Positives = 558/865 (65%), Gaps = 46/865 (5%)

Query  5    YRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIA  63
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKTMQRNWIGRSEGVEITFNVNDYDNT  242
            V RK + QW +KITAYA+ LL+DL+ +D WP+++K MQRNWIG+S G ++TF+V+D D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGCTYLAVAAGHPLAQ--KAAENNPELAAFIDECR-NTKVAEAEMATME  299
            +TV+TTRPDT+ G TY  +A+ H+L +   ++++   +A +  +   ++ +A +++A  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGVDTGFKAVHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPV  359
            K GV TG  A++P+ G E+PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L+I PV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  360  ILAADGSEPDLSQQALTEKGVLFNSGEFNGLDHEAAFNAIADKLTAMGVGERKVNYRLRD  419
            +        ++ + A+TE G+ +NS+ ++GLD  +A+  + + L A GVG+ +V YRLRD
Sbjct  362  L-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMVTLEDGTVMPTPDDQLPVILP--EDVVMDGI-NSPIKADPEWAKT  476
            W  SRQRYWG PIP++  EDGT  + P+ +LP++LP   D+   G  +SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  T-VNGMPALRETDTFDTFMESSWYYARYTCPEYKEGMLDSEAANYWLPVDIYIGGIEHAI  535
            T  +G+ + RET+T      SSWYY RY  P+  E + D E  + WLPVDIY+GG EHA+
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVER  595
            +HLLY RF HK++ D G+V + EP ++L+ QGM+L+ ++      + R  + + D +  R
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEKR  591

Query  596  DEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMT  655
            D  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D +
Sbjct  592  D--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  656  LEWQESGVEGANRFLKRVWKLVYEHTAKGDVAALNVDALTEDQKALRRDVHKTIAKVTDD  715
            + W E G+EG+ +FL RV +L+   T+K        +   E+  AL +  + T+  VT++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLI---TTK--------EITEENSGALDKVYNETVKAVTEQ  695

Query  716  IGRRQTFNTAIAAIMELMNKLAKAPTDGEQDRALMQEALLAVVRMLNPFTPHICFTLWQE  775
            +++ + FNTAIA +M ++N        ++++  L  +   + V+++ PF+PH+   LWQ 
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  776  LKGEGD-IDNAPWPVADEKAMVEDSTLVVVQVNGKVRAKITVPVDATEEQVRERAGQEHL  834
            L + G+ I   PWP  DE  +VE+   +VVQ++GKV+AK+ V+ D + E+++E A  ++ 
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  835  VAKYLDGVTVRKVIYVPGKLLNLVV  859
            V   + G  + KVI VP KL+N+V+
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVI  832

1162) leuS in NC_012967


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  541 bits (2043),  Expect = 6e-155, Method: Compositional matrix adjust.
 Identities = 361/865 (42%), Positives = 558/865 (65%), Gaps = 46/865 (5%)

Query  5    YRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIA  63
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKTMQRNWIGRSEGVEITFNVNDYDNT  242
            V RK + QW +KITAYA+ LL+DL+ +D WP+++K MQRNWIG+S G ++TF+V+D D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGCTYLAVAAGHPLAQ--KAAENNPELAAFIDECR-NTKVAEAEMATME  299
            +TV+TTRPDT+ G TY  +A+ H+L +   ++++   +A +  +   ++ +A +++A  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGVDTGFKAVHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPV  359
            K GV TG  A++P+ G E+PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L+I PV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  360  ILAADGSEPDLSQQALTEKGVLFNSGEFNGLDHEAAFNAIADKLTAMGVGERKVNYRLRD  419
            +        ++ + A+TE G+ +NS+ ++GLD  +A+  + + L A GVG+ +V YRLRD
Sbjct  362  L-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMVTLEDGTVMPTPDDQLPVILP--EDVVMDGI-NSPIKADPEWAKT  476
            W  SRQRYWG PIP++  EDGT  + P+ +LP++LP   D+   G  +SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  T-VNGMPALRETDTFDTFMESSWYYARYTCPEYKEGMLDSEAANYWLPVDIYIGGIEHAI  535
            T  +G+ + RET+T      SSWYY RY  P+  E + D E  + WLPVDIY+GG EHA+
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVER  595
            +HLLY RF HK++ D G+V + EP ++L+ QGM+L+ ++      + R  + + D +  R
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEKR  591

Query  596  DEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMT  655
            D  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D +
Sbjct  592  D--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  656  LEWQESGVEGANRFLKRVWKLVYEHTAKGDVAALNVDALTEDQKALRRDVHKTIAKVTDD  715
            + W E G+EG+ +FL RV +L+   T+K        +   E+  AL +  + T+  VT++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLI---TTK--------EITEENSGALDKVYNETVKAVTEQ  695

Query  716  IGRRQTFNTAIAAIMELMNKLAKAPTDGEQDRALMQEALLAVVRMLNPFTPHICFTLWQE  775
            +++ + FNTAIA +M ++N        ++++  L  +   + V+++ PF+PH+   LWQ 
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  776  LKGEGD-IDNAPWPVADEKAMVEDSTLVVVQVNGKVRAKITVPVDATEEQVRERAGQEHL  834
            L + G+ I   PWP  DE  +VE+   +VVQ++GKV+AK+ V+ D + E+++E A  ++ 
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  835  VAKYLDGVTVRKVIYVPGKLLNLVV  859
            V   + G  + KVI VP KL+N+V+
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVI  832

1163) leuS in NC_004431


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  541 bits (2043),  Expect = 6e-155, Method: Compositional matrix adjust.
 Identities = 361/865 (42%), Positives = 556/865 (65%), Gaps = 46/865 (5%)

Query  52   YRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIA  110
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  111  RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSR  170
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  171  ELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  229
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  230  VERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKTMQRNWIGRSEGVEITFNVNDYDNT  289
            V RK + QW +KITAYA+ LL+DL+ +D WP+++K MQRNWIG+S G ++TF+V+D D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  290  LTVYTTRPDTFMGCTYLAVAAGHPLAQ--KAAENNPELAAFIDECR-NTKVAEAEMATME  346
            +TV+TTRPDT+ G TY  +A+ H+L +   ++++   +A +  +   ++ +A +++A  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  347  KKGVDTGFKAVHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPV  406
            K GV TG  A++P+ G E+PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L+I PV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  407  ILAADGSEPDLSQQALTEKGVLFNSGEFNGLDHEAAFNAIADKLTAMGVGERKVNYRLRD  466
            +        ++ + A+TE G+ +NS+ ++GLD  +A+  + + L A GVG+ +V YRLRD
Sbjct  362  L-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  467  WGVSRQRYWGAPIPMVTLEDGTVMPTPDDQLPVILP--EDVVMDGIT-SPIKADPEWAKT  523
            W  SRQRYWG PIP++  EDGT  + P+ +LP++LP   D+   G   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  524  T-VNGMPALRETDTFDTFMESSWYYARYTCPEYKEGMLDSKAANYWLPVDIYIGGIEHAI  582
            T  +G+ + RET+T      SSWYY RY  P+  E + D    + WLPVDIY+GG EHA+
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  583  MHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVER  642
            +HLLY RF HK++ D G+V + EP ++L+ QGM+L+ +  Y +  G    + + D +  R
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS--YRDSRGA---LVATDKVEKR  591

Query  643  DEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMT  702
            D  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D +
Sbjct  592  D--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  703  LEWQESGVEGANRFLKRVWKLVYEHTAKGDVAALNVDALTEDQKALRRDVHKTIAKVTDD  762
            + W E G+EG+ +FL RV +L+   T+K        +   E+  AL +  + T+  VT++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLI---TTK--------EITEENSGALDKVYNETVKAVTEQ  695

Query  763  IGRRQTFNTAIAAIMELMNKLAKAPTDGEQDRALMQEALLAVVRMLNPFTPHICFTLWQE  822
            +++ + FNTAIA +M ++N        ++++  L  +   + V+++ PF+PH+   LWQ 
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  823  LKGEGD-IDNAPWPVADEKAMVEDSTLVVVQVNGKVRAKITVPVDATEEQVRERAGQEHL  881
            L + G+ I   PWP  DE  +VE+   +VVQ++GKV+AK+ V+ D + E+++E A  ++ 
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  882  VAKYLDGVTVRKVIYVPGKLLNLVV  906
            V   + G  + KVI VP KL+N+V+
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVI  832

1164) leuS in NC_017652


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  541 bits (2043),  Expect = 6e-155, Method: Compositional matrix adjust.
 Identities = 361/865 (42%), Positives = 556/865 (65%), Gaps = 46/865 (5%)

Query  52   YRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIA  110
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  111  RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSR  170
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  171  ELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  229
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  230  VERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKTMQRNWIGRSEGVEITFNVNDYDNT  289
            V RK + QW +KITAYA+ LL+DL+ +D WP+++K MQRNWIG+S G ++TF+V+D D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  290  LTVYTTRPDTFMGCTYLAVAAGHPLAQ--KAAENNPELAAFIDECR-NTKVAEAEMATME  346
            +TV+TTRPDT+ G TY  +A+ H+L +   ++++   +A +  +   ++ +A +++A  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  347  KKGVDTGFKAVHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPV  406
            K GV TG  A++P+ G E+PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L+I PV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  407  ILAADGSEPDLSQQALTEKGVLFNSGEFNGLDHEAAFNAIADKLTAMGVGERKVNYRLRD  466
            +        ++ + A+TE G+ +NS+ ++GLD  +A+  + + L A GVG+ +V YRLRD
Sbjct  362  L-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  467  WGVSRQRYWGAPIPMVTLEDGTVMPTPDDQLPVILP--EDVVMDGIT-SPIKADPEWAKT  523
            W  SRQRYWG PIP++  EDGT  + P+ +LP++LP   D+   G   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  524  T-VNGMPALRETDTFDTFMESSWYYARYTCPEYKEGMLDSKAANYWLPVDIYIGGIEHAI  582
            T  +G+ + RET+T      SSWYY RY  P+  E + D    + WLPVDIY+GG EHA+
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  583  MHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVER  642
            +HLLY RF HK++ D G+V + EP ++L+ QGM+L+ +  Y +  G    + + D +  R
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS--YRDSRGA---LVATDKVEKR  591

Query  643  DEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMT  702
            D  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D +
Sbjct  592  D--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  703  LEWQESGVEGANRFLKRVWKLVYEHTAKGDVAALNVDALTEDQKALRRDVHKTIAKVTDD  762
            + W E G+EG+ +FL RV +L+   T+K        +   E+  AL +  + T+  VT++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLI---TTK--------EITEENSGALDKVYNETVKAVTEQ  695

Query  763  IGRRQTFNTAIAAIMELMNKLAKAPTDGEQDRALMQEALLAVVRMLNPFTPHICFTLWQE  822
            +++ + FNTAIA +M ++N        ++++  L  +   + V+++ PF+PH+   LWQ 
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  823  LKGEGD-IDNAPWPVADEKAMVEDSTLVVVQVNGKVRAKITVPVDATEEQVRERAGQEHL  881
            L + G+ I   PWP  DE  +VE+   +VVQ++GKV+AK+ V+ D + E+++E A  ++ 
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  882  VAKYLDGVTVRKVIYVPGKLLNLVV  906
            V   + G  + KVI VP KL+N+V+
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVI  832

1165) leuS in NC_017651


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  541 bits (2043),  Expect = 6e-155, Method: Compositional matrix adjust.
 Identities = 361/865 (42%), Positives = 556/865 (65%), Gaps = 46/865 (5%)

Query  52   YRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIA  110
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  111  RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSR  170
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  171  ELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  229
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  230  VERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKTMQRNWIGRSEGVEITFNVNDYDNT  289
            V RK + QW +KITAYA+ LL+DL+ +D WP+++K MQRNWIG+S G ++TF+V+D D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  290  LTVYTTRPDTFMGCTYLAVAAGHPLAQ--KAAENNPELAAFIDECR-NTKVAEAEMATME  346
            +TV+TTRPDT+ G TY  +A+ H+L +   ++++   +A +  +   ++ +A +++A  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  347  KKGVDTGFKAVHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPV  406
            K GV TG  A++P+ G E+PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L+I PV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  407  ILAADGSEPDLSQQALTEKGVLFNSGEFNGLDHEAAFNAIADKLTAMGVGERKVNYRLRD  466
            +        ++ + A+TE G+ +NS+ ++GLD  +A+  + + L A GVG+ +V YRLRD
Sbjct  362  L-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  467  WGVSRQRYWGAPIPMVTLEDGTVMPTPDDQLPVILP--EDVVMDGIT-SPIKADPEWAKT  523
            W  SRQRYWG PIP++  EDGT  + P+ +LP++LP   D+   G   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  524  T-VNGMPALRETDTFDTFMESSWYYARYTCPEYKEGMLDSKAANYWLPVDIYIGGIEHAI  582
            T  +G+ + RET+T      SSWYY RY  P+  E + D    + WLPVDIY+GG EHA+
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  583  MHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVER  642
            +HLLY RF HK++ D G+V + EP ++L+ QGM+L+ +  Y +  G    + + D +  R
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS--YRDSRGA---LVATDKVEKR  591

Query  643  DEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMT  702
            D  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D +
Sbjct  592  D--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  703  LEWQESGVEGANRFLKRVWKLVYEHTAKGDVAALNVDALTEDQKALRRDVHKTIAKVTDD  762
            + W E G+EG+ +FL RV +L+   T+K        +   E+  AL +  + T+  VT++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLI---TTK--------EITEENSGALDKVYNETVKAVTEQ  695

Query  763  IGRRQTFNTAIAAIMELMNKLAKAPTDGEQDRALMQEALLAVVRMLNPFTPHICFTLWQE  822
            +++ + FNTAIA +M ++N        ++++  L  +   + V+++ PF+PH+   LWQ 
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  823  LKGEGD-IDNAPWPVADEKAMVEDSTLVVVQVNGKVRAKITVPVDATEEQVRERAGQEHL  881
            L + G+ I   PWP  DE  +VE+   +VVQ++GKV+AK+ V+ D + E+++E A  ++ 
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  882  VAKYLDGVTVRKVIYVPGKLLNLVV  906
            V   + G  + KVI VP KL+N+V+
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVI  832

1166) leuS in NC_011353


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  541 bits (2043),  Expect = 6e-155, Method: Compositional matrix adjust.
 Identities = 361/865 (42%), Positives = 557/865 (65%), Gaps = 46/865 (5%)

Query  5    YRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIA  63
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKTMQRNWIGRSEGVEITFNVNDYDNT  242
            V RK + QW +KITAYA+ LL+DL+ +D WP+++K MQRNWIG+S G ++TF+V+D D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGCTYLAVAAGHPLAQ--KAAENNPELAAFIDECR-NTKVAEAEMATME  299
            +TV+TTRPDT+ G TY  +A+ H+L +   ++++   +A +  +   ++ +A +++A  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGVNTGFKAVHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPV  359
            K GV TG  A++P+ G E+PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L+I PV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  360  ILAADGSEPDLSQQALTEKGVLFNSGEFNGLDHEAAFNAIADKLTAMGVGERKVNYRLRD  419
            +        ++ + A+TE G+ +NS+ ++GLD  +A+  + + L A GVG+ +V YRLRD
Sbjct  362  L-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMVTLEDGTVMPTPDDQLPVILP--EDVVMDGIT-SPIKADPQWAKT  476
            W  SRQRYWG PIP++  EDGT  + P+ +LP++LP   D+   G   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  T-VNGMPALRETDTFDTFMESSWYYARYTCPEYKEGMLDSEAANYWLPVDIYIGGIEHAI  535
            T  +G+ + RET+T      SSWYY RY  P+  E + D E  + WLPVDIY+GG EHA+
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVER  595
            +HLLY RF HK++ D G+V + EP ++L+ QGM+L+ ++      + R  + + D +  R
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEKR  591

Query  596  DEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMT  655
            D  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D +
Sbjct  592  D--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  656  LEWQESGVEGANRFLKRVWKLVYEHTAKGDVAALNVDALTEDQKALRRDVHKTIAKVTDD  715
            + W E G+EG+ +FL RV +L+   T+K        +   E+  AL +  + T+  VT++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLI---TTK--------EITEENSGALDKVYNETVKAVTEQ  695

Query  716  IGRRQTFNTAIAAIMELMNKLAKAPTDGEQDRALMQEALLAVVRMLNPFTPHICFTLWQE  775
            +++ + FNTAIA +M ++N        ++++  L  +   + V+++ PF+PH+   LWQ 
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  776  LKGEGD-IDNAPWPVADEKAMVEDSTLVVVQVNGKVRAKITVPVDATEEQVRERAGQEHL  834
            L + G+ I   PWP  DE  +VE+   +VVQ++GKV+AK+ V+ D + E+++E A  ++ 
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  835  VAKYLDGVTVRKVIYVPGKLLNLVV  859
            V   + G  + KVI VP KL+N+V+
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVI  832

1167) leuS in NC_002655


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  541 bits (2043),  Expect = 6e-155, Method: Compositional matrix adjust.
 Identities = 361/865 (42%), Positives = 557/865 (65%), Gaps = 46/865 (5%)

Query  5    YRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIA  63
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKTMQRNWIGRSEGVEITFNVNDYDNT  242
            V RK + QW +KITAYA+ LL+DL+ +D WP+++K MQRNWIG+S G ++TF+V+D D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGCTYLAVAAGHPLAQ--KAAENNPELAAFIDECR-NTKVAEAEMATME  299
            +TV+TTRPDT+ G TY  +A+ H+L +   ++++   +A +  +   ++ +A +++A  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGVNTGFKAVHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPV  359
            K GV TG  A++P+ G E+PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L+I PV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  360  ILAADGSEPDLSQQALTEKGVLFNSGEFNGLDHEAAFNAIADKLTAMGVGERKVNYRLRD  419
            +        ++ + A+TE G+ +NS+ ++GLD  +A+  + + L A GVG+ +V YRLRD
Sbjct  362  L-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMVTLEDGTVMPTPDDQLPVILP--EDVVMDGIT-SPIKADPQWAKT  476
            W  SRQRYWG PIP++  EDGT  + P+ +LP++LP   D+   G   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  T-VNGMPALRETDTFDTFMESSWYYARYTCPEYKEGMLDSEAANYWLPVDIYIGGIEHAI  535
            T  +G+ + RET+T      SSWYY RY  P+  E + D E  + WLPVDIY+GG EHA+
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVER  595
            +HLLY RF HK++ D G+V + EP ++L+ QGM+L+ ++      + R  + + D +  R
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEKR  591

Query  596  DEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMT  655
            D  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D +
Sbjct  592  D--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  656  LEWQESGVEGANRFLKRVWKLVYEHTAKGDVAALNVDALTEDQKALRRDVHKTIAKVTDD  715
            + W E G+EG+ +FL RV +L+   T+K        +   E+  AL +  + T+  VT++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLI---TTK--------EITEENSGALDKVYNETVKAVTEQ  695

Query  716  IGRRQTFNTAIAAIMELMNKLAKAPTDGEQDRALMQEALLAVVRMLNPFTPHICFTLWQE  775
            +++ + FNTAIA +M ++N        ++++  L  +   + V+++ PF+PH+   LWQ 
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  776  LKGEGD-IDNAPWPVADEKAMVEDSTLVVVQVNGKVRAKITVPVDATEEQVRERAGQEHL  834
            L + G+ I   PWP  DE  +VE+   +VVQ++GKV+AK+ V+ D + E+++E A  ++ 
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  835  VAKYLDGVTVRKVIYVPGKLLNLVV  859
            V   + G  + KVI VP KL+N+V+
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVI  832

1168) leuS in NC_002695


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  541 bits (2043),  Expect = 6e-155, Method: Compositional matrix adjust.
 Identities = 361/865 (42%), Positives = 557/865 (65%), Gaps = 46/865 (5%)

Query  5    YRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIA  63
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKTMQRNWIGRSEGVEITFNVNDYDNT  242
            V RK + QW +KITAYA+ LL+DL+ +D WP+++K MQRNWIG+S G ++TF+V+D D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGCTYLAVAAGHPLAQ--KAAENNPELAAFIDECR-NTKVAEAEMATME  299
            +TV+TTRPDT+ G TY  +A+ H+L +   ++++   +A +  +   ++ +A +++A  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGVNTGFKAVHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPV  359
            K GV TG  A++P+ G E+PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L+I PV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  360  ILAADGSEPDLSQQALTEKGVLFNSGEFNGLDHEAAFNAIADKLTAMGVGERKVNYRLRD  419
            +        ++ + A+TE G+ +NS+ ++GLD  +A+  + + L A GVG+ +V YRLRD
Sbjct  362  L-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMVTLEDGTVMPTPDDQLPVILP--EDVVMDGIT-SPIKADPQWAKT  476
            W  SRQRYWG PIP++  EDGT  + P+ +LP++LP   D+   G   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  T-VNGMPALRETDTFDTFMESSWYYARYTCPEYKEGMLDSEAANYWLPVDIYIGGIEHAI  535
            T  +G+ + RET+T      SSWYY RY  P+  E + D E  + WLPVDIY+GG EHA+
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVER  595
            +HLLY RF HK++ D G+V + EP ++L+ QGM+L+ ++      + R  + + D +  R
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEKR  591

Query  596  DEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMT  655
            D  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D +
Sbjct  592  D--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  656  LEWQESGVEGANRFLKRVWKLVYEHTAKGDVAALNVDALTEDQKALRRDVHKTIAKVTDD  715
            + W E G+EG+ +FL RV +L+   T+K        +   E+  AL +  + T+  VT++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLI---TTK--------EITEENSGALDKVYNETVKAVTEQ  695

Query  716  IGRRQTFNTAIAAIMELMNKLAKAPTDGEQDRALMQEALLAVVRMLNPFTPHICFTLWQE  775
            +++ + FNTAIA +M ++N        ++++  L  +   + V+++ PF+PH+   LWQ 
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  776  LKGEGD-IDNAPWPVADEKAMVEDSTLVVVQVNGKVRAKITVPVDATEEQVRERAGQEHL  834
            L + G+ I   PWP  DE  +VE+   +VVQ++GKV+AK+ V+ D + E+++E A  ++ 
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  835  VAKYLDGVTVRKVIYVPGKLLNLVV  859
            V   + G  + KVI VP KL+N+V+
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVI  832

1169) leuS in NC_013008


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  541 bits (2043),  Expect = 6e-155, Method: Compositional matrix adjust.
 Identities = 361/865 (42%), Positives = 557/865 (65%), Gaps = 46/865 (5%)

Query  5    YRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIA  63
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKTMQRNWIGRSEGVEITFNVNDYDNT  242
            V RK + QW +KITAYA+ LL+DL+ +D WP+++K MQRNWIG+S G ++TF+V+D D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGCTYLAVAAGHPLAQ--KAAENNPELAAFIDECR-NTKVAEAEMATME  299
            +TV+TTRPDT+ G TY  +A+ H+L +   ++++   +A +  +   ++ +A +++A  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGVNTGFKAVHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPV  359
            K GV TG  A++P+ G E+PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L+I PV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  360  ILAADGSEPDLSQQALTEKGVLFNSGEFNGLDHEAAFNAIADKLTAMGVGERKVNYRLRD  419
            +        ++ + A+TE G+ +NS+ ++GLD  +A+  + + L A GVG+ +V YRLRD
Sbjct  362  L-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMVTLEDGTVMPTPDDQLPVILP--EDVVMDGIT-SPIKADPQWAKT  476
            W  SRQRYWG PIP++  EDGT  + P+ +LP++LP   D+   G   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  T-VNGMPALRETDTFDTFMESSWYYARYTCPEYKEGMLDSEAANYWLPVDIYIGGIEHAI  535
            T  +G+ + RET+T      SSWYY RY  P+  E + D E  + WLPVDIY+GG EHA+
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVER  595
            +HLLY RF HK++ D G+V + EP ++L+ QGM+L+ ++      + R  + + D +  R
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEKR  591

Query  596  DEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMT  655
            D  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D +
Sbjct  592  D--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  656  LEWQESGVEGANRFLKRVWKLVYEHTAKGDVAALNVDALTEDQKALRRDVHKTIAKVTDD  715
            + W E G+EG+ +FL RV +L+   T+K        +   E+  AL +  + T+  VT++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLI---TTK--------EITEENSGALDKVYNETVKAVTEQ  695

Query  716  IGRRQTFNTAIAAIMELMNKLAKAPTDGEQDRALMQEALLAVVRMLNPFTPHICFTLWQE  775
            +++ + FNTAIA +M ++N        ++++  L  +   + V+++ PF+PH+   LWQ 
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  776  LKGEGD-IDNAPWPVADEKAMVEDSTLVVVQVNGKVRAKITVPVDATEEQVRERAGQEHL  834
            L + G+ I   PWP  DE  +VE+   +VVQ++GKV+AK+ V+ D + E+++E A  ++ 
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  835  VAKYLDGVTVRKVIYVPGKLLNLVV  859
            V   + G  + KVI VP KL+N+V+
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVI  832

1170) leuS in NC_013941


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  541 bits (2043),  Expect = 6e-155, Method: Compositional matrix adjust.
 Identities = 361/865 (42%), Positives = 557/865 (65%), Gaps = 46/865 (5%)

Query  5    YRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIA  63
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKTMQRNWIGRSEGVEITFNVNDYDNT  242
            V RK + QW +KITAYA+ LL+DL+ +D WP+++K MQRNWIG+S G ++TF+V+D D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGCTYLAVAAGHPLAQ--KAAENNPELAAFIDECR-NTKVAEAEMATME  299
            +TV+TTRPDT+ G TY  +A+ H+L +   ++++   +A +  +   ++ +A +++A  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGVNTGFKAVHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPV  359
            K GV TG  A++P+ G E+PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L+I PV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  360  ILAADGSEPDLSQQALTEKGVLFNSGEFNGLDHEAAFNAIADKLTAMGVGERKVNYRLRD  419
            +        ++ + A+TE G+ +NS+ ++GLD  +A+  + + L A GVG+ +V YRLRD
Sbjct  362  L-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMVTLEDGTVMPTPDDQLPVILP--EDVVMDGIT-SPIKADPQWAKT  476
            W  SRQRYWG PIP++  EDGT  + P+ +LP++LP   D+   G   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  T-VNGMPALRETDTFDTFMESSWYYARYTCPEYKEGMLDSEAANYWLPVDIYIGGIEHAI  535
            T  +G+ + RET+T      SSWYY RY  P+  E + D E  + WLPVDIY+GG EHA+
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVER  595
            +HLLY RF HK++ D G+V + EP ++L+ QGM+L+ ++      + R  + + D +  R
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEKR  591

Query  596  DEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMT  655
            D  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D +
Sbjct  592  D--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  656  LEWQESGVEGANRFLKRVWKLVYEHTAKGDVAALNVDALTEDQKALRRDVHKTIAKVTDD  715
            + W E G+EG+ +FL RV +L+   T+K        +   E+  AL +  + T+  VT++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLI---TTK--------EITEENSGALDKVYNETVKAVTEQ  695

Query  716  IGRRQTFNTAIAAIMELMNKLAKAPTDGEQDRALMQEALLAVVRMLNPFTPHICFTLWQE  775
            +++ + FNTAIA +M ++N        ++++  L  +   + V+++ PF+PH+   LWQ 
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  776  LKGEGD-IDNAPWPVADEKAMVEDSTLVVVQVNGKVRAKITVPVDATEEQVRERAGQEHL  834
            L + G+ I   PWP  DE  +VE+   +VVQ++GKV+AK+ V+ D + E+++E A  ++ 
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  835  VAKYLDGVTVRKVIYVPGKLLNLVV  859
            V   + G  + KVI VP KL+N+V+
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVI  832

1171) leuS in NC_017656


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  541 bits (2043),  Expect = 6e-155, Method: Compositional matrix adjust.
 Identities = 361/865 (42%), Positives = 557/865 (65%), Gaps = 46/865 (5%)

Query  5    YRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIA  63
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKTMQRNWIGRSEGVEITFNVNDYDNT  242
            V RK + QW +KITAYA+ LL+DL+ +D WP+++K MQRNWIG+S G ++TF+V+D D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGCTYLAVAAGHPLAQ--KAAENNPELAAFIDECR-NTKVAEAEMATME  299
            +TV+TTRPDT+ G TY  +A+ H+L +   ++++   +A +  +   ++ +A +++A  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGVNTGFKAVHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPV  359
            K GV TG  A++P+ G E+PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L+I PV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  360  ILAADGSEPDLSQQALTEKGVLFNSGEFNGLDHEAAFNAIADKLTAMGVGERKVNYRLRD  419
            +        ++ + A+TE G+ +NS+ ++GLD  +A+  + + L A GVG+ +V YRLRD
Sbjct  362  L-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMVTLEDGTVMPTPDDQLPVILP--EDVVMDGIT-SPIKADPQWAKT  476
            W  SRQRYWG PIP++  EDGT  + P+ +LP++LP   D+   G   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  T-VNGMPALRETDTFDTFMESSWYYARYTCPEYKEGMLDSEAANYWLPVDIYIGGIEHAI  535
            T  +G+ + RET+T      SSWYY RY  P+  E + D E  + WLPVDIY+GG EHA+
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVER  595
            +HLLY RF HK++ D G+V + EP ++L+ QGM+L+ ++      + R  + + D +  R
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEKR  591

Query  596  DEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMT  655
            D  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D +
Sbjct  592  D--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  656  LEWQESGVEGANRFLKRVWKLVYEHTAKGDVAALNVDALTEDQKALRRDVHKTIAKVTDD  715
            + W E G+EG+ +FL RV +L+   T+K        +   E+  AL +  + T+  VT++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLI---TTK--------EITEENSGALDKVYNETVKAVTEQ  695

Query  716  IGRRQTFNTAIAAIMELMNKLAKAPTDGEQDRALMQEALLAVVRMLNPFTPHICFTLWQE  775
            +++ + FNTAIA +M ++N        ++++  L  +   + V+++ PF+PH+   LWQ 
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  776  LKGEGD-IDNAPWPVADEKAMVEDSTLVVVQVNGKVRAKITVPVDATEEQVRERAGQEHL  834
            L + G+ I   PWP  DE  +VE+   +VVQ++GKV+AK+ V+ D + E+++E A  ++ 
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  835  VAKYLDGVTVRKVIYVPGKLLNLVV  859
            V   + G  + KVI VP KL+N+V+
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVI  832

1172) leuS in NC_017906


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  541 bits (2043),  Expect = 6e-155, Method: Compositional matrix adjust.
 Identities = 361/865 (42%), Positives = 557/865 (65%), Gaps = 46/865 (5%)

Query  5    YRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIA  63
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKTMQRNWIGRSEGVEITFNVNDYDNT  242
            V RK + QW +KITAYA+ LL+DL+ +D WP+++K MQRNWIG+S G ++TF+V+D D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGCTYLAVAAGHPLAQ--KAAENNPELAAFIDECR-NTKVAEAEMATME  299
            +TV+TTRPDT+ G TY  +A+ H+L +   ++++   +A +  +   ++ +A +++A  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGVNTGFKAVHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPV  359
            K GV TG  A++P+ G E+PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L+I PV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  360  ILAADGSEPDLSQQALTEKGVLFNSGEFNGLDHEAAFNAIADKLTAMGVGERKVNYRLRD  419
            +        ++ + A+TE G+ +NS+ ++GLD  +A+  + + L A GVG+ +V YRLRD
Sbjct  362  L-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMVTLEDGTVMPTPDDQLPVILP--EDVVMDGIT-SPIKADPQWAKT  476
            W  SRQRYWG PIP++  EDGT  + P+ +LP++LP   D+   G   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  T-VNGMPALRETDTFDTFMESSWYYARYTCPEYKEGMLDSEAANYWLPVDIYIGGIEHAI  535
            T  +G+ + RET+T      SSWYY RY  P+  E + D E  + WLPVDIY+GG EHA+
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVER  595
            +HLLY RF HK++ D G+V + EP ++L+ QGM+L+ ++      + R  + + D +  R
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEKR  591

Query  596  DEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMT  655
            D  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D +
Sbjct  592  D--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  656  LEWQESGVEGANRFLKRVWKLVYEHTAKGDVAALNVDALTEDQKALRRDVHKTIAKVTDD  715
            + W E G+EG+ +FL RV +L+   T+K        +   E+  AL +  + T+  VT++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLI---TTK--------EITEENSGALDKVYNETVKAVTEQ  695

Query  716  IGRRQTFNTAIAAIMELMNKLAKAPTDGEQDRALMQEALLAVVRMLNPFTPHICFTLWQE  775
            +++ + FNTAIA +M ++N        ++++  L  +   + V+++ PF+PH+   LWQ 
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  776  LKGEGD-IDNAPWPVADEKAMVEDSTLVVVQVNGKVRAKITVPVDATEEQVRERAGQEHL  834
            L + G+ I   PWP  DE  +VE+   +VVQ++GKV+AK+ V+ D + E+++E A  ++ 
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  835  VAKYLDGVTVRKVIYVPGKLLNLVV  859
            V   + G  + KVI VP KL+N+V+
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVI  832

1173) Daes_2821 in NC_014844


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  541 bits (2042),  Expect = 7e-155, Method: Compositional matrix adjust.
 Identities = 367/867 (43%), Positives = 550/867 (64%), Gaps = 76/867 (8%)

Query  6    YDPQAVERKWQRIWQESGCFEVEVDPSRPKYYVLEMFPYPSGK-IHMGHVRNYSIGDVVA  64
            YD  A+E KWQ +W ++  F    D+S+PK+Y L+MFPYPSG  +H+GH   Y+  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  65   RFKSMQGFNVLHPMGWDAFGLPAENAAIKHGVHPAAWTYQNIAEMREQLQRLGYSYDWRR  124
            RFK  QG NVLHPMGWDAFGLPAE+ A+  G +PA  T +NIA+ + Q++ LG+SYDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  125  EIASCRPEYYKWEQKFFLKFLEKGLAYRKHSPQNWCPDCNTVLANEQV-EDGKCWRCDSE  183
            E+ +  P+YYKW Q +F K+ EKGLAY  + P NW  +  T +ANE+V  DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  184  VEQKDMEQWFLRITdyadelladldsleGGWPERVLTMQRNWIGRSYGAELTFQVKDMDH  243
            V +K M QW L+IT YA+ LL DL+ +  +WPE +  MQRNWIG+S GA++TF+VKD D 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV--DWPESIKDMQRNWIGKSTGANVTFKVKDTDK  241

Query  244  TIPVFTTRPDTLFGATFMSVAAEHPLVDILTADAPDKAEVDAFVANIRNMDRIKRGADDL  303
             + VFTTRPDTLFGAT+  +A+EH+LVD +T+     A V  +  +      + R     
Sbjct  242  DFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEA-VADYKRQASLKSDLARTDLAK  300

Query  304  EKEGVFTGKYCVNPVTGALMPIYVANFVLMGYGTGAVMAVPAHDQRDFEFARKYELPLKV  363
            EK GV TG Y +NPV G  MP+ +A++VL +YGTGA+MAVPAHD+RD EFA++++L +  
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  364  VINPADLHARGEVLAEADLTAAYADPGILVNSGDFDGMDNESAKKAIVEHLDKSGLGTMA  423
            V++ ++++            AA+++ G+ +NS+ +DG+D+ SA   +VE L+  G+G   
Sbjct  361  VLEGGNVEE-----------AAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNEN  409

Query  424  VNYRLRDWNVSRQRFWGAPIPVIYCDACGVVPVPEDQLPILLPVDAQVRSDGK--SPLPT  481
            V YRLRDW  SRQR+WG PIP+I  +     +VPE +LP++LPV  ++R+ G   SPL+ 
Sbjct  410  VTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLAN  469

Query  482  MDSFVNCVCPACGKPARRETDTFDTFFESSWYYLRYCDPRNEDAPFSQEATGYWMNVDQY  541
            +   ++ V    G  +RRET+T      SSWYYLRY DP+N +    +E    W+ VD Y
Sbjct  470  VTDWLE-VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIY  528

Query  542  IGGIEHAILHLLYSRFFTKALRDTGFVQASEPFANLLTQGMVL-----------------  584
            +GG EHA+LHLLY+RF  K L D G V + EPF +L+ QGM+L                 
Sbjct  529  VGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKV  588

Query  585  --KDG---------------GKMSKSKGNVVDPNSMIERYGADATRLFILFASPPIKELE  627
              +DG               +KMSKS  NVV+P+ ++E+YGAD+ R++ +F +P    + 
Sbjct  589  EKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIA  648

Query  628  WSDQGIEGAFRFLSRLWRLVEELEDRLHAVRPTSHAAPKSDAARQLRFKEHDTVRRVTRD  687
            WS++G+EG+ +FL R+ RL+            T + +  + +A +  +  ++TV+ VT +
Sbjct  649  WSEEGLEGSRKFLDRVYRLI-----------TTKEITEENSGALDKVY--NETVKAVTEQ  695

Query  688  IENEFQFNTAIAAVMELVNEMYALKDELADTEPKALASAIATAVTLLSPVAPHLCEELWQ  747
            ++ + +FNTAIA +M +VN         A+ E K ++      V L++P APHL EELWQ
Sbjct  696  VD-QMKFNTAIAQLMVFVNA--------ANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  748  TM-GHAETLATQSWPTFDESALVKDEVTLVVQVNGKVRGKFeapnnapaaeVETIALGLE  806
            ++ + +E+++  +WP++DES LV ++V +VVQ++GKV++K+  +++ +  E++ +AL+ E
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  807  NVAKFIEGSTVRKVIVIPNKLVNIVAN  833
            +V   I G  + KVI +PNKLVNIV +
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVIK  833

1174) leuS in NC_017632


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  541 bits (2042),  Expect = 7e-155, Method: Compositional matrix adjust.
 Identities = 360/865 (42%), Positives = 554/865 (65%), Gaps = 46/865 (5%)

Query  5    YRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIA  63
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCTPEYYRWEQKCFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W Q  FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKTMQRNWIGRSEGVEITFNVKDYDNT  242
            V RK + QW +KITAYA+ LL+DL+ +D WP+++K MQRNWIG+S G ++TF+VKD D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGCTYLAVAAGHPLAQ--KAAENNPELAAFIDECR-NTKVAEAEMATME  299
            +TV+TTRPDT+ G TY  +A+ H+L +   ++++   +A +  +   ++ +A +++A  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGVDTGFKAVHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPV  359
            K GV TG  A++P+ G E+PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L+I PV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  360  ILAADGSEPDLSQQALTEKGVLFNSGEFNGLDHEAAFNAIADKLTEMGVGERKVNYRLRD  419
            +        ++ + A+TE G+ +NS+ ++GLD  +A+  + + L   GVG+ +V YRLRD
Sbjct  362  L-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMVTLEDGTVMPTPDDQLPVILP--EDVVMDGIT-SPIKADPEWAKT  476
            W  SRQRYWG PIP++  EDGT  + P+ +LP++LP   D+   G   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  T-VNGMPALRETDTFDTFMESSWYYARYTCPEYKEGMLDSKAANYWLPVDIYIGGIEHAI  535
            T  +G+ + RET+T      SSWYY RY  P+  E + D    + WLPVDIY+GG EHA+
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVER  595
            +HLLY RF HK++ D G+V + EP ++L+ QGM+L+ ++      + R  + + D +  R
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEKR  591

Query  596  DEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMT  655
            D  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D +
Sbjct  592  D--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  656  LEWQESGVEGANRFLKRVWKLVYEHTAKGDVAALNVDALTEDQKALRRDVHKTIAKVTDD  715
            + W E G+EG+ +FL RV +L+   T+K        +   E+  AL +  + T+  VT++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLI---TTK--------EITEENSGALDKVYNETVKAVTEQ  695

Query  716  IGRRQTFNTAIAAIMELMNKLAKAPTDGEQDRALMQEALLAVVRMLNPFTPHICFTLWQE  775
            +++ + FNTAIA +M ++N        ++++  L  +   + V+++ PF+PH+   LWQ 
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  776  LKGEGD-IDNAPWPVADEKAMVEDSTLVVVQVNGKVRAKITVPVDATEEQVRERAGQEHL  834
            L + G+ I   PWP  DE  +VE+   +VVQ++GKV+AK+ V+ D + E+++E A  ++ 
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  835  VAKYLDGVTVRKVIYVPGKLLNLVV  859
            V   + G  + KVI VP KL+N+V+
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVI  832

1175) leuS in NC_007613


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  541 bits (2042),  Expect = 7e-155, Method: Compositional matrix adjust.
 Identities = 361/865 (42%), Positives = 557/865 (65%), Gaps = 46/865 (5%)

Query  5    YRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIA  63
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKSMQRNWIGRSEGVEITFNVNDYDNT  242
            V RK + QW +KITAYA+ LL+DL+ +D WP+++K MQRNWIG+S G ++TF+V+D D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGCTYLAVAAGHPLAQ--KAAENNPELAAFIDECR-NTKVAEAEMATME  299
            +TV+TTRPDT+ G TY  +A+ H+L +   ++++   +A +  +   ++ +A +++A  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGVDTGFKAVHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPV  359
            K GV TG  A++P+ G E+PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L+I PV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  360  ILAADGSEPDLSQQALTEKGVLFNSGEFNGLDHEAAFNAIADKLTAMGVGERKVNYRLRD  419
            +        ++ + A+TE G+ +NS+ ++GLD  +A+  + + L A GVG+ +V YRLRD
Sbjct  362  L-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMVTLEDGTVMPTPDDQLPVILP--EDVVMDGIT-SPIKADPEWAKT  476
            W  SRQRYWG PIP++  EDGT  + P+ +LP++LP   D+   G   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  T-VNGMPALRETDTFDTFMESSWYYARYTCPEYKEGMLDSEAANYWLPVDIYIGGIEHAI  535
            T  +G+ + RET+T      SSWYY RY  P+  E + D E  + WLPVDIY+GG EHA+
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVER  595
            +HLLY RF HK++ D G+V + EP ++L+ QGM+L+ ++      + R  + + D +  R
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEKR  591

Query  596  DEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMT  655
            D  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D +
Sbjct  592  D--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  656  LEWQESGVEGANRFLKRVWKLVYEHTAKGDVAALNVDALTEDQKALRRDVHKTIAKVTDD  715
            + W E G+EG+ +FL RV +L+   T+K        +   E+  AL +  + T+  VT++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLI---TTK--------EITEENSGALDKVYNETVKAVTEQ  695

Query  716  IGRRQTFNTAIAAIMELMNKLAKAPTDGEQDRALMQEALLAVVRMLNPFTPHICFTLWQE  775
            +++ + FNTAIA +M ++N        ++++  L  +   + V+++ PF+PH+   LWQ 
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  776  LKGEGD-IDNAPWPVADEKAMVEDSTLVVVQVNGKVRAKITVPVDATEEQVRERAGQEHL  834
            L + G+ I   PWP  DE  +VE+   +VVQ++GKV+AK+ V+ D + E+++E A  ++ 
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  835  VAKYLDGVTVRKVIYVPGKLLNLVV  859
            V   + G  + KVI VP KL+N+V+
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVI  832

1176) leuS in NC_017626


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  541 bits (2041),  Expect = 8e-155, Method: Compositional matrix adjust.
 Identities = 361/865 (42%), Positives = 557/865 (65%), Gaps = 46/865 (5%)

Query  5    YRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIA  63
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKTMQRNWIGRSEGVEITFNVNDYDNT  242
            V RK + QW +KITAYA+ LL+DL+ +D WP+++K MQRNWIG+S G ++TF+V+D D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGCTYLAVAAGHPLAQ--KAAENNPELAAFIDECR-NTKVAEAEMATME  299
            +TV+TTRPDT+ G TY  +A+ H+L +   ++++   +A +  +   ++ +A +++A  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGVDTGFKAVHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPV  359
            K GV TG  A++P+ G E+PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L+I PV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  360  ILAADGSEPDLSQQALTEKGVLFNSGEFNGLDHEAAFNAIADKLTAMGVGERKVNYRLRD  419
            +        ++ + A+TE G+ +NS+ ++GLD  +A+  + + L A GVG+ +V YRLRD
Sbjct  362  L-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMVTLEDGTVMPTPDDQLPVILP--EDVVMDGIT-SPIKADPEWAKT  476
            W  SRQRYWG PIP++  EDGT  + P+ +LP++LP   D+   G   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  T-VNGMPALRETDTFDTFMESSWYYARYTCPEYKEGMLDSEAANYWLPVDIYIGGIEHAI  535
            T  +G+ + RET+T      SSWYY RY  P+  E + D E  + WLPVDIY+GG EHA+
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVER  595
            +HLLY RF HK++ D G+V + EP ++L+ QGM+L+ ++      + R  + + D +  R
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEKR  591

Query  596  DEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMT  655
            D  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D +
Sbjct  592  D--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  656  LEWQESGVEGANRFLKRVWKLVYEHTAKGDVAALNVDALTEDQKALRRDVHKTIAKVTDD  715
            + W E G+EG+ +FL RV +L+   T+K        +   E+  AL +  + T+  VT++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLI---TTK--------EITEENSGALDKVYNETVKAVTEQ  695

Query  716  IGRRQTFNTAIAAIMELMNKLAKAPTDGEQDRALMQEALLAVVRMLNPFTPHICFTLWQE  775
            +++ + FNTAIA +M ++N        ++++  L  +   + V+++ PF+PH+   LWQ 
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  776  LKGEGD-IDNAPWPVADEKAMVEDSTLVVVQVNGKVRAKITVPVDATEEQVRERAGQEHL  834
            L + G+ I   PWP  DE  +VE+   +VVQ++GKV+AK+ V+ D + E+++E A  ++ 
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  835  VAKYLDGVTVRKVIYVPGKLLNLVV  859
            V   + G  + KVI VP KL+N+V+
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVI  832

1177) leuS in NC_011748


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  541 bits (2041),  Expect = 8e-155, Method: Compositional matrix adjust.
 Identities = 361/865 (42%), Positives = 557/865 (65%), Gaps = 46/865 (5%)

Query  5    YRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIA  63
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKTMQRNWIGRSEGVEITFNVNDYDNT  242
            V RK + QW +KITAYA+ LL+DL+ +D WP+++K MQRNWIG+S G ++TF+V+D D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGCTYLAVAAGHPLAQ--KAAENNPELAAFIDECR-NTKVAEAEMATME  299
            +TV+TTRPDT+ G TY  +A+ H+L +   ++++   +A +  +   ++ +A +++A  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGVDTGFKAVHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPV  359
            K GV TG  A++P+ G E+PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L+I PV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  360  ILAADGSEPDLSQQALTEKGVLFNSGEFNGLDHEAAFNAIADKLTAMGVGERKVNYRLRD  419
            +        ++ + A+TE G+ +NS+ ++GLD  +A+  + + L A GVG+ +V YRLRD
Sbjct  362  L-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMVTLEDGTVMPTPDDQLPVILP--EDVVMDGIT-SPIKADPEWAKT  476
            W  SRQRYWG PIP++  EDGT  + P+ +LP++LP   D+   G   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  T-VNGMPALRETDTFDTFMESSWYYARYTCPEYKEGMLDSEAANYWLPVDIYIGGIEHAI  535
            T  +G+ + RET+T      SSWYY RY  P+  E + D E  + WLPVDIY+GG EHA+
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVER  595
            +HLLY RF HK++ D G+V + EP ++L+ QGM+L+ ++      + R  + + D +  R
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEKR  591

Query  596  DEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMT  655
            D  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D +
Sbjct  592  D--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  656  LEWQESGVEGANRFLKRVWKLVYEHTAKGDVAALNVDALTEDQKALRRDVHKTIAKVTDD  715
            + W E G+EG+ +FL RV +L+   T+K        +   E+  AL +  + T+  VT++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLI---TTK--------EITEENSGALDKVYNETVKAVTEQ  695

Query  716  IGRRQTFNTAIAAIMELMNKLAKAPTDGEQDRALMQEALLAVVRMLNPFTPHICFTLWQE  775
            +++ + FNTAIA +M ++N        ++++  L  +   + V+++ PF+PH+   LWQ 
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  776  LKGEGD-IDNAPWPVADEKAMVEDSTLVVVQVNGKVRAKITVPVDATEEQVRERAGQEHL  834
            L + G+ I   PWP  DE  +VE+   +VVQ++GKV+AK+ V+ D + E+++E A  ++ 
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  835  VAKYLDGVTVRKVIYVPGKLLNLVV  859
            V   + G  + KVI VP KL+N+V+
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVI  832

1178) leuS in NC_020163


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  541 bits (2041),  Expect = 8e-155, Method: Compositional matrix adjust.
 Identities = 361/865 (42%), Positives = 557/865 (65%), Gaps = 46/865 (5%)

Query  5    YRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIA  63
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKTMQRNWIGRSEGVEITFNVNDYDNT  242
            V RK + QW +KITAYA+ LL+DL+ +D WP+++K MQRNWIG+S G ++TF+V+D D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGCTYLAVAAGHPLAQ--KAAENNPELAAFIDECR-NTKVAEAEMATME  299
            +TV+TTRPDT+ G TY  +A+ H+L +   ++++   +A +  +   ++ +A +++A  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGVDTGFKAVHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPV  359
            K GV TG  A++P+ G E+PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L+I PV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  360  ILAADGSEPDLSQQALTEKGVLFNSGEFNGLDHEAAFNAIADKLTAMGVGERKVNYRLRD  419
            +        ++ + A+TE G+ +NS+ ++GLD  +A+  + + L A GVG+ +V YRLRD
Sbjct  362  L-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMVTLEDGTVMPTPDDQLPVILP--EDVVMDGIT-SPIKADPEWAKT  476
            W  SRQRYWG PIP++  EDGT  + P+ +LP++LP   D+   G   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  T-VNGMPALRETDTFDTFMESSWYYARYTCPEYKEGMLDSEAANYWLPVDIYIGGIEHAI  535
            T  +G+ + RET+T      SSWYY RY  P+  E + D E  + WLPVDIY+GG EHA+
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVER  595
            +HLLY RF HK++ D G+V + EP ++L+ QGM+L+ ++      + R  + + D +  R
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEKR  591

Query  596  DEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMT  655
            D  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D +
Sbjct  592  D--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  656  LEWQESGVEGANRFLKRVWKLVYEHTAKGDVAALNVDALTEDQKALRRDVHKTIAKVTDD  715
            + W E G+EG+ +FL RV +L+   T+K        +   E+  AL +  + T+  VT++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLI---TTK--------EITEENSGALDKVYNETVKAVTEQ  695

Query  716  IGRRQTFNTAIAAIMELMNKLAKAPTDGEQDRALMQEALLAVVRMLNPFTPHICFTLWQE  775
            +++ + FNTAIA +M ++N        ++++  L  +   + V+++ PF+PH+   LWQ 
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  776  LKGEGD-IDNAPWPVADEKAMVEDSTLVVVQVNGKVRAKITVPVDATEEQVRERAGQEHL  834
            L + G+ I   PWP  DE  +VE+   +VVQ++GKV+AK+ V+ D + E+++E A  ++ 
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  835  VAKYLDGVTVRKVIYVPGKLLNLVV  859
            V   + G  + KVI VP KL+N+V+
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVI  832

1179) leuS in NC_011741


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  541 bits (2041),  Expect = 8e-155, Method: Compositional matrix adjust.
 Identities = 361/865 (42%), Positives = 557/865 (65%), Gaps = 46/865 (5%)

Query  5    YRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIA  63
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKTMQRNWIGRSEGVEITFNVNDYDNT  242
            V RK + QW +KITAYA+ LL+DL+ +D WP+++K MQRNWIG+S G ++TF+V+D D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGCTYLAVAAGHPLAQ--KAAENNPELAAFIDECR-NTKVAEAEMATME  299
            +TV+TTRPDT+ G TY  +A+ H+L +   ++++   +A +  +   ++ +A +++A  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGVDTGFKAVHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPV  359
            K GV TG  A++P+ G E+PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L+I PV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  360  ILAADGSEPDLSQQALTEKGVLFNSGEFNGLDHEAAFNAIADKLTAMGVGERKVNYRLRD  419
            +        ++ + A+TE G+ +NS+ ++GLD  +A+  + + L A GVG+ +V YRLRD
Sbjct  362  L-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMVTLEDGTVMPTPDDQLPVILP--EDVVMDGIT-SPIKADPEWAKT  476
            W  SRQRYWG PIP++  EDGT  + P+ +LP++LP   D+   G   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  T-VNGMPALRETDTFDTFMESSWYYARYTCPEYKEGMLDSEAANYWLPVDIYIGGIEHAI  535
            T  +G+ + RET+T      SSWYY RY  P+  E + D E  + WLPVDIY+GG EHA+
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVER  595
            +HLLY RF HK++ D G+V + EP ++L+ QGM+L+ ++      + R  + + D +  R
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEKR  591

Query  596  DEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMT  655
            D  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D +
Sbjct  592  D--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  656  LEWQESGVEGANRFLKRVWKLVYEHTAKGDVAALNVDALTEDQKALRRDVHKTIAKVTDD  715
            + W E G+EG+ +FL RV +L+   T+K        +   E+  AL +  + T+  VT++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLI---TTK--------EITEENSGALDKVYNETVKAVTEQ  695

Query  716  IGRRQTFNTAIAAIMELMNKLAKAPTDGEQDRALMQEALLAVVRMLNPFTPHICFTLWQE  775
            +++ + FNTAIA +M ++N        ++++  L  +   + V+++ PF+PH+   LWQ 
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  776  LKGEGD-IDNAPWPVADEKAMVEDSTLVVVQVNGKVRAKITVPVDATEEQVRERAGQEHL  834
            L + G+ I   PWP  DE  +VE+   +VVQ++GKV+AK+ V+ D + E+++E A  ++ 
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  835  VAKYLDGVTVRKVIYVPGKLLNLVV  859
            V   + G  + KVI VP KL+N+V+
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVI  832

1180) leuS in NC_017660


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  541 bits (2041),  Expect = 8e-155, Method: Compositional matrix adjust.
 Identities = 361/865 (42%), Positives = 557/865 (65%), Gaps = 46/865 (5%)

Query  5    YRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIA  63
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKTMQRNWIGRSEGVEITFNVNDYDNT  242
            V RK + QW +KITAYA+ LL+DL+ +D WP+++K MQRNWIG+S G ++TF+V+D D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGCTYLAVAAGHPLAQ--KAAENNPELAAFIDECR-NTKVAEAEMATME  299
            +TV+TTRPDT+ G TY  +A+ H+L +   ++++   +A +  +   ++ +A +++A  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGVDTGFKAVHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPV  359
            K GV TG  A++P+ G E+PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L+I PV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  360  ILAADGSEPDLSQQALTEKGVLFNSGEFNGLDHEAAFNAIADKLTAMGVGERKVNYRLRD  419
            +        ++ + A+TE G+ +NS+ ++GLD  +A+  + + L A GVG+ +V YRLRD
Sbjct  362  L-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMVTLEDGTVMPTPDDQLPVILP--EDVVMDGIT-SPIKADPEWAKT  476
            W  SRQRYWG PIP++  EDGT  + P+ +LP++LP   D+   G   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  T-VNGMPALRETDTFDTFMESSWYYARYTCPEYKEGMLDSEAANYWLPVDIYIGGIEHAI  535
            T  +G+ + RET+T      SSWYY RY  P+  E + D E  + WLPVDIY+GG EHA+
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVER  595
            +HLLY RF HK++ D G+V + EP ++L+ QGM+L+ ++      + R  + + D +  R
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEKR  591

Query  596  DEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMT  655
            D  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D +
Sbjct  592  D--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  656  LEWQESGVEGANRFLKRVWKLVYEHTAKGDVAALNVDALTEDQKALRRDVHKTIAKVTDD  715
            + W E G+EG+ +FL RV +L+   T+K        +   E+  AL +  + T+  VT++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLI---TTK--------EITEENSGALDKVYNETVKAVTEQ  695

Query  716  IGRRQTFNTAIAAIMELMNKLAKAPTDGEQDRALMQEALLAVVRMLNPFTPHICFTLWQE  775
            +++ + FNTAIA +M ++N        ++++  L  +   + V+++ PF+PH+   LWQ 
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  776  LKGEGD-IDNAPWPVADEKAMVEDSTLVVVQVNGKVRAKITVPVDATEEQVRERAGQEHL  834
            L + G+ I   PWP  DE  +VE+   +VVQ++GKV+AK+ V+ D + E+++E A  ++ 
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  835  VAKYLDGVTVRKVIYVPGKLLNLVV  859
            V   + G  + KVI VP KL+N+V+
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVI  832

1181) EKO11_3224 in NC_016902


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  541 bits (2041),  Expect = 8e-155, Method: Compositional matrix adjust.
 Identities = 361/865 (42%), Positives = 557/865 (65%), Gaps = 46/865 (5%)

Query  5    YRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIA  63
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKTMQRNWIGRSEGVEITFNVNDYDNT  242
            V RK + QW +KITAYA+ LL+DL+ +D WP+++K MQRNWIG+S G ++TF+V+D D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGCTYLAVAAGHPLAQ--KAAENNPELAAFIDECR-NTKVAEAEMATME  299
            +TV+TTRPDT+ G TY  +A+ H+L +   ++++   +A +  +   ++ +A +++A  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGVDTGFKAVHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPV  359
            K GV TG  A++P+ G E+PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L+I PV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  360  ILAADGSEPDLSQQALTEKGVLFNSGEFNGLDHEAAFNAIADKLTAMGVGERKVNYRLRD  419
            +        ++ + A+TE G+ +NS+ ++GLD  +A+  + + L A GVG+ +V YRLRD
Sbjct  362  L-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMVTLEDGTVMPTPDDQLPVILP--EDVVMDGIT-SPIKADPEWAKT  476
            W  SRQRYWG PIP++  EDGT  + P+ +LP++LP   D+   G   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  T-VNGMPALRETDTFDTFMESSWYYARYTCPEYKEGMLDSEAANYWLPVDIYIGGIEHAI  535
            T  +G+ + RET+T      SSWYY RY  P+  E + D E  + WLPVDIY+GG EHA+
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVER  595
            +HLLY RF HK++ D G+V + EP ++L+ QGM+L+ ++      + R  + + D +  R
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEKR  591

Query  596  DEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMT  655
            D  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D +
Sbjct  592  D--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  656  LEWQESGVEGANRFLKRVWKLVYEHTAKGDVAALNVDALTEDQKALRRDVHKTIAKVTDD  715
            + W E G+EG+ +FL RV +L+   T+K        +   E+  AL +  + T+  VT++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLI---TTK--------EITEENSGALDKVYNETVKAVTEQ  695

Query  716  IGRRQTFNTAIAAIMELMNKLAKAPTDGEQDRALMQEALLAVVRMLNPFTPHICFTLWQE  775
            +++ + FNTAIA +M ++N        ++++  L  +   + V+++ PF+PH+   LWQ 
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  776  LKGEGD-IDNAPWPVADEKAMVEDSTLVVVQVNGKVRAKITVPVDATEEQVRERAGQEHL  834
            L + G+ I   PWP  DE  +VE+   +VVQ++GKV+AK+ V+ D + E+++E A  ++ 
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  835  VAKYLDGVTVRKVIYVPGKLLNLVV  859
            V   + G  + KVI VP KL+N+V+
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVI  832

1182) leuS in NC_022364


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  541 bits (2041),  Expect = 8e-155, Method: Compositional matrix adjust.
 Identities = 361/865 (42%), Positives = 557/865 (65%), Gaps = 46/865 (5%)

Query  5    YRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIA  63
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKTMQRNWIGRSEGVEITFNVNDYDNT  242
            V RK + QW +KITAYA+ LL+DL+ +D WP+++K MQRNWIG+S G ++TF+V+D D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGCTYLAVAAGHPLAQ--KAAENNPELAAFIDECR-NTKVAEAEMATME  299
            +TV+TTRPDT+ G TY  +A+ H+L +   ++++   +A +  +   ++ +A +++A  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGVDTGFKAVHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPV  359
            K GV TG  A++P+ G E+PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L+I PV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  360  ILAADGSEPDLSQQALTEKGVLFNSGEFNGLDHEAAFNAIADKLTAMGVGERKVNYRLRD  419
            +        ++ + A+TE G+ +NS+ ++GLD  +A+  + + L A GVG+ +V YRLRD
Sbjct  362  L-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMVTLEDGTVMPTPDDQLPVILP--EDVVMDGIT-SPIKADPEWAKT  476
            W  SRQRYWG PIP++  EDGT  + P+ +LP++LP   D+   G   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  T-VNGMPALRETDTFDTFMESSWYYARYTCPEYKEGMLDSEAANYWLPVDIYIGGIEHAI  535
            T  +G+ + RET+T      SSWYY RY  P+  E + D E  + WLPVDIY+GG EHA+
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVER  595
            +HLLY RF HK++ D G+V + EP ++L+ QGM+L+ ++      + R  + + D +  R
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEKR  591

Query  596  DEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMT  655
            D  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D +
Sbjct  592  D--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  656  LEWQESGVEGANRFLKRVWKLVYEHTAKGDVAALNVDALTEDQKALRRDVHKTIAKVTDD  715
            + W E G+EG+ +FL RV +L+   T+K        +   E+  AL +  + T+  VT++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLI---TTK--------EITEENSGALDKVYNETVKAVTEQ  695

Query  716  IGRRQTFNTAIAAIMELMNKLAKAPTDGEQDRALMQEALLAVVRMLNPFTPHICFTLWQE  775
            +++ + FNTAIA +M ++N        ++++  L  +   + V+++ PF+PH+   LWQ 
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  776  LKGEGD-IDNAPWPVADEKAMVEDSTLVVVQVNGKVRAKITVPVDATEEQVRERAGQEHL  834
            L + G+ I   PWP  DE  +VE+   +VVQ++GKV+AK+ V+ D + E+++E A  ++ 
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  835  VAKYLDGVTVRKVIYVPGKLLNLVV  859
            V   + G  + KVI VP KL+N+V+
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVI  832

1183) leuS in NC_013353


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  541 bits (2041),  Expect = 8e-155, Method: Compositional matrix adjust.
 Identities = 361/865 (42%), Positives = 557/865 (65%), Gaps = 46/865 (5%)

Query  5    YRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIA  63
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKTMQRNWIGRSEGVEITFNVNDYDNT  242
            V RK + QW +KITAYA+ LL+DL+ +D WP+++K MQRNWIG+S G ++TF+V+D D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGCTYLAVAAGHPLAQ--KAAENNPELAAFIDECR-NTKVAEAEMATME  299
            +TV+TTRPDT+ G TY  +A+ H+L +   ++++   +A +  +   ++ +A +++A  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGVDTGFKAVHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPV  359
            K GV TG  A++P+ G E+PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L+I PV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  360  ILAADGSEPDLSQQALTEKGVLFNSGEFNGLDHEAAFNAIADKLTAMGVGERKVNYRLRD  419
            +        ++ + A+TE G+ +NS+ ++GLD  +A+  + + L A GVG+ +V YRLRD
Sbjct  362  L-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMVTLEDGTVMPTPDDQLPVILP--EDVVMDGIT-SPIKADPEWAKT  476
            W  SRQRYWG PIP++  EDGT  + P+ +LP++LP   D+   G   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  T-VNGMPALRETDTFDTFMESSWYYARYTCPEYKEGMLDSEAANYWLPVDIYIGGIEHAI  535
            T  +G+ + RET+T      SSWYY RY  P+  E + D E  + WLPVDIY+GG EHA+
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVER  595
            +HLLY RF HK++ D G+V + EP ++L+ QGM+L+ ++      + R  + + D +  R
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEKR  591

Query  596  DEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMT  655
            D  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D +
Sbjct  592  D--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  656  LEWQESGVEGANRFLKRVWKLVYEHTAKGDVAALNVDALTEDQKALRRDVHKTIAKVTDD  715
            + W E G+EG+ +FL RV +L+   T+K        +   E+  AL +  + T+  VT++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLI---TTK--------EITEENSGALDKVYNETVKAVTEQ  695

Query  716  IGRRQTFNTAIAAIMELMNKLAKAPTDGEQDRALMQEALLAVVRMLNPFTPHICFTLWQE  775
            +++ + FNTAIA +M ++N        ++++  L  +   + V+++ PF+PH+   LWQ 
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  776  LKGEGD-IDNAPWPVADEKAMVEDSTLVVVQVNGKVRAKITVPVDATEEQVRERAGQEHL  834
            L + G+ I   PWP  DE  +VE+   +VVQ++GKV+AK+ V+ D + E+++E A  ++ 
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  835  VAKYLDGVTVRKVIYVPGKLLNLVV  859
            V   + G  + KVI VP KL+N+V+
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVI  832

1184) leuS in NC_018650


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  541 bits (2041),  Expect = 8e-155, Method: Compositional matrix adjust.
 Identities = 361/865 (42%), Positives = 557/865 (65%), Gaps = 46/865 (5%)

Query  5    YRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIA  63
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKTMQRNWIGRSEGVEITFNVNDYDNT  242
            V RK + QW +KITAYA+ LL+DL+ +D WP+++K MQRNWIG+S G ++TF+V+D D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGCTYLAVAAGHPLAQ--KAAENNPELAAFIDECR-NTKVAEAEMATME  299
            +TV+TTRPDT+ G TY  +A+ H+L +   ++++   +A +  +   ++ +A +++A  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGVDTGFKAVHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPV  359
            K GV TG  A++P+ G E+PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L+I PV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  360  ILAADGSEPDLSQQALTEKGVLFNSGEFNGLDHEAAFNAIADKLTAMGVGERKVNYRLRD  419
            +        ++ + A+TE G+ +NS+ ++GLD  +A+  + + L A GVG+ +V YRLRD
Sbjct  362  L-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMVTLEDGTVMPTPDDQLPVILP--EDVVMDGIT-SPIKADPEWAKT  476
            W  SRQRYWG PIP++  EDGT  + P+ +LP++LP   D+   G   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  T-VNGMPALRETDTFDTFMESSWYYARYTCPEYKEGMLDSEAANYWLPVDIYIGGIEHAI  535
            T  +G+ + RET+T      SSWYY RY  P+  E + D E  + WLPVDIY+GG EHA+
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVER  595
            +HLLY RF HK++ D G+V + EP ++L+ QGM+L+ ++      + R  + + D +  R
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEKR  591

Query  596  DEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMT  655
            D  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D +
Sbjct  592  D--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  656  LEWQESGVEGANRFLKRVWKLVYEHTAKGDVAALNVDALTEDQKALRRDVHKTIAKVTDD  715
            + W E G+EG+ +FL RV +L+   T+K        +   E+  AL +  + T+  VT++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLI---TTK--------EITEENSGALDKVYNETVKAVTEQ  695

Query  716  IGRRQTFNTAIAAIMELMNKLAKAPTDGEQDRALMQEALLAVVRMLNPFTPHICFTLWQE  775
            +++ + FNTAIA +M ++N        ++++  L  +   + V+++ PF+PH+   LWQ 
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  776  LKGEGD-IDNAPWPVADEKAMVEDSTLVVVQVNGKVRAKITVPVDATEEQVRERAGQEHL  834
            L + G+ I   PWP  DE  +VE+   +VVQ++GKV+AK+ V+ D + E+++E A  ++ 
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  835  VAKYLDGVTVRKVIYVPGKLLNLVV  859
            V   + G  + KVI VP KL+N+V+
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVI  832

1185) leuS in NC_018661


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  541 bits (2041),  Expect = 8e-155, Method: Compositional matrix adjust.
 Identities = 361/865 (42%), Positives = 557/865 (65%), Gaps = 46/865 (5%)

Query  5    YRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIA  63
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKTMQRNWIGRSEGVEITFNVNDYDNT  242
            V RK + QW +KITAYA+ LL+DL+ +D WP+++K MQRNWIG+S G ++TF+V+D D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGCTYLAVAAGHPLAQ--KAAENNPELAAFIDECR-NTKVAEAEMATME  299
            +TV+TTRPDT+ G TY  +A+ H+L +   ++++   +A +  +   ++ +A +++A  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGVDTGFKAVHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPV  359
            K GV TG  A++P+ G E+PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L+I PV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  360  ILAADGSEPDLSQQALTEKGVLFNSGEFNGLDHEAAFNAIADKLTAMGVGERKVNYRLRD  419
            +        ++ + A+TE G+ +NS+ ++GLD  +A+  + + L A GVG+ +V YRLRD
Sbjct  362  L-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMVTLEDGTVMPTPDDQLPVILP--EDVVMDGIT-SPIKADPEWAKT  476
            W  SRQRYWG PIP++  EDGT  + P+ +LP++LP   D+   G   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  T-VNGMPALRETDTFDTFMESSWYYARYTCPEYKEGMLDSEAANYWLPVDIYIGGIEHAI  535
            T  +G+ + RET+T      SSWYY RY  P+  E + D E  + WLPVDIY+GG EHA+
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVER  595
            +HLLY RF HK++ D G+V + EP ++L+ QGM+L+ ++      + R  + + D +  R
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEKR  591

Query  596  DEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMT  655
            D  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D +
Sbjct  592  D--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  656  LEWQESGVEGANRFLKRVWKLVYEHTAKGDVAALNVDALTEDQKALRRDVHKTIAKVTDD  715
            + W E G+EG+ +FL RV +L+   T+K        +   E+  AL +  + T+  VT++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLI---TTK--------EITEENSGALDKVYNETVKAVTEQ  695

Query  716  IGRRQTFNTAIAAIMELMNKLAKAPTDGEQDRALMQEALLAVVRMLNPFTPHICFTLWQE  775
            +++ + FNTAIA +M ++N        ++++  L  +   + V+++ PF+PH+   LWQ 
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  776  LKGEGD-IDNAPWPVADEKAMVEDSTLVVVQVNGKVRAKITVPVDATEEQVRERAGQEHL  834
            L + G+ I   PWP  DE  +VE+   +VVQ++GKV+AK+ V+ D + E+++E A  ++ 
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  835  VAKYLDGVTVRKVIYVPGKLLNLVV  859
            V   + G  + KVI VP KL+N+V+
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVI  832

1186) leuS in NC_018658


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  541 bits (2041),  Expect = 8e-155, Method: Compositional matrix adjust.
 Identities = 361/865 (42%), Positives = 557/865 (65%), Gaps = 46/865 (5%)

Query  5    YRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIA  63
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKTMQRNWIGRSEGVEITFNVNDYDNT  242
            V RK + QW +KITAYA+ LL+DL+ +D WP+++K MQRNWIG+S G ++TF+V+D D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGCTYLAVAAGHPLAQ--KAAENNPELAAFIDECR-NTKVAEAEMATME  299
            +TV+TTRPDT+ G TY  +A+ H+L +   ++++   +A +  +   ++ +A +++A  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGVDTGFKAVHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPV  359
            K GV TG  A++P+ G E+PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L+I PV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  360  ILAADGSEPDLSQQALTEKGVLFNSGEFNGLDHEAAFNAIADKLTAMGVGERKVNYRLRD  419
            +        ++ + A+TE G+ +NS+ ++GLD  +A+  + + L A GVG+ +V YRLRD
Sbjct  362  L-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMVTLEDGTVMPTPDDQLPVILP--EDVVMDGIT-SPIKADPEWAKT  476
            W  SRQRYWG PIP++  EDGT  + P+ +LP++LP   D+   G   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  T-VNGMPALRETDTFDTFMESSWYYARYTCPEYKEGMLDSEAANYWLPVDIYIGGIEHAI  535
            T  +G+ + RET+T      SSWYY RY  P+  E + D E  + WLPVDIY+GG EHA+
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVER  595
            +HLLY RF HK++ D G+V + EP ++L+ QGM+L+ ++      + R  + + D +  R
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEKR  591

Query  596  DEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMT  655
            D  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D +
Sbjct  592  D--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  656  LEWQESGVEGANRFLKRVWKLVYEHTAKGDVAALNVDALTEDQKALRRDVHKTIAKVTDD  715
            + W E G+EG+ +FL RV +L+   T+K        +   E+  AL +  + T+  VT++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLI---TTK--------EITEENSGALDKVYNETVKAVTEQ  695

Query  716  IGRRQTFNTAIAAIMELMNKLAKAPTDGEQDRALMQEALLAVVRMLNPFTPHICFTLWQE  775
            +++ + FNTAIA +M ++N        ++++  L  +   + V+++ PF+PH+   LWQ 
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  776  LKGEGD-IDNAPWPVADEKAMVEDSTLVVVQVNGKVRAKITVPVDATEEQVRERAGQEHL  834
            L + G+ I   PWP  DE  +VE+   +VVQ++GKV+AK+ V+ D + E+++E A  ++ 
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  835  VAKYLDGVTVRKVIYVPGKLLNLVV  859
            V   + G  + KVI VP KL+N+V+
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVI  832

1187) leuS in NC_013364


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  541 bits (2041),  Expect = 8e-155, Method: Compositional matrix adjust.
 Identities = 361/865 (42%), Positives = 557/865 (65%), Gaps = 46/865 (5%)

Query  5    YRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIA  63
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKTMQRNWIGRSEGVEITFNVNDYDNT  242
            V RK + QW +KITAYA+ LL+DL+ +D WP+++K MQRNWIG+S G ++TF+V+D D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGCTYLAVAAGHPLAQ--KAAENNPELAAFIDECR-NTKVAEAEMATME  299
            +TV+TTRPDT+ G TY  +A+ H+L +   ++++   +A +  +   ++ +A +++A  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGVDTGFKAVHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPV  359
            K GV TG  A++P+ G E+PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L+I PV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  360  ILAADGSEPDLSQQALTEKGVLFNSGEFNGLDHEAAFNAIADKLTAMGVGERKVNYRLRD  419
            +        ++ + A+TE G+ +NS+ ++GLD  +A+  + + L A GVG+ +V YRLRD
Sbjct  362  L-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMVTLEDGTVMPTPDDQLPVILP--EDVVMDGIT-SPIKADPEWAKT  476
            W  SRQRYWG PIP++  EDGT  + P+ +LP++LP   D+   G   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  T-VNGMPALRETDTFDTFMESSWYYARYTCPEYKEGMLDSEAANYWLPVDIYIGGIEHAI  535
            T  +G+ + RET+T      SSWYY RY  P+  E + D E  + WLPVDIY+GG EHA+
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVER  595
            +HLLY RF HK++ D G+V + EP ++L+ QGM+L+ ++      + R  + + D +  R
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEKR  591

Query  596  DEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMT  655
            D  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D +
Sbjct  592  D--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  656  LEWQESGVEGANRFLKRVWKLVYEHTAKGDVAALNVDALTEDQKALRRDVHKTIAKVTDD  715
            + W E G+EG+ +FL RV +L+   T+K        +   E+  AL +  + T+  VT++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLI---TTK--------EITEENSGALDKVYNETVKAVTEQ  695

Query  716  IGRRQTFNTAIAAIMELMNKLAKAPTDGEQDRALMQEALLAVVRMLNPFTPHICFTLWQE  775
            +++ + FNTAIA +M ++N        ++++  L  +   + V+++ PF+PH+   LWQ 
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  776  LKGEGD-IDNAPWPVADEKAMVEDSTLVVVQVNGKVRAKITVPVDATEEQVRERAGQEHL  834
            L + G+ I   PWP  DE  +VE+   +VVQ++GKV+AK+ V+ D + E+++E A  ++ 
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  835  VAKYLDGVTVRKVIYVPGKLLNLVV  859
            V   + G  + KVI VP KL+N+V+
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVI  832

1188) leuS in NC_013361


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  541 bits (2041),  Expect = 8e-155, Method: Compositional matrix adjust.
 Identities = 361/865 (42%), Positives = 557/865 (65%), Gaps = 46/865 (5%)

Query  5    YRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIA  63
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKTMQRNWIGRSEGVEITFNVNDYDNT  242
            V RK + QW +KITAYA+ LL+DL+ +D WP+++K MQRNWIG+S G ++TF+V+D D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGCTYLAVAAGHPLAQ--KAAENNPELAAFIDECR-NTKVAEAEMATME  299
            +TV+TTRPDT+ G TY  +A+ H+L +   ++++   +A +  +   ++ +A +++A  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGVDTGFKAVHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPV  359
            K GV TG  A++P+ G E+PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L+I PV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  360  ILAADGSEPDLSQQALTEKGVLFNSGEFNGLDHEAAFNAIADKLTAMGVGERKVNYRLRD  419
            +        ++ + A+TE G+ +NS+ ++GLD  +A+  + + L A GVG+ +V YRLRD
Sbjct  362  L-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMVTLEDGTVMPTPDDQLPVILP--EDVVMDGIT-SPIKADPEWAKT  476
            W  SRQRYWG PIP++  EDGT  + P+ +LP++LP   D+   G   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  T-VNGMPALRETDTFDTFMESSWYYARYTCPEYKEGMLDSEAANYWLPVDIYIGGIEHAI  535
            T  +G+ + RET+T      SSWYY RY  P+  E + D E  + WLPVDIY+GG EHA+
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVER  595
            +HLLY RF HK++ D G+V + EP ++L+ QGM+L+ ++      + R  + + D +  R
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEKR  591

Query  596  DEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMT  655
            D  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D +
Sbjct  592  D--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  656  LEWQESGVEGANRFLKRVWKLVYEHTAKGDVAALNVDALTEDQKALRRDVHKTIAKVTDD  715
            + W E G+EG+ +FL RV +L+   T+K        +   E+  AL +  + T+  VT++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLI---TTK--------EITEENSGALDKVYNETVKAVTEQ  695

Query  716  IGRRQTFNTAIAAIMELMNKLAKAPTDGEQDRALMQEALLAVVRMLNPFTPHICFTLWQE  775
            +++ + FNTAIA +M ++N        ++++  L  +   + V+++ PF+PH+   LWQ 
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  776  LKGEGD-IDNAPWPVADEKAMVEDSTLVVVQVNGKVRAKITVPVDATEEQVRERAGQEHL  834
            L + G+ I   PWP  DE  +VE+   +VVQ++GKV+AK+ V+ D + E+++E A  ++ 
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  835  VAKYLDGVTVRKVIYVPGKLLNLVV  859
            V   + G  + KVI VP KL+N+V+
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVI  832

1189) leuS in NC_017635


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  541 bits (2041),  Expect = 8e-155, Method: Compositional matrix adjust.
 Identities = 361/865 (42%), Positives = 557/865 (65%), Gaps = 46/865 (5%)

Query  5    YRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIA  63
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKTMQRNWIGRSEGVEITFNVNDYDNT  242
            V RK + QW +KITAYA+ LL+DL+ +D WP+++K MQRNWIG+S G ++TF+V+D D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGCTYLAVAAGHPLAQ--KAAENNPELAAFIDECR-NTKVAEAEMATME  299
            +TV+TTRPDT+ G TY  +A+ H+L +   ++++   +A +  +   ++ +A +++A  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGVDTGFKAVHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPV  359
            K GV TG  A++P+ G E+PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L+I PV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  360  ILAADGSEPDLSQQALTEKGVLFNSGEFNGLDHEAAFNAIADKLTAMGVGERKVNYRLRD  419
            +        ++ + A+TE G+ +NS+ ++GLD  +A+  + + L A GVG+ +V YRLRD
Sbjct  362  L-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMVTLEDGTVMPTPDDQLPVILP--EDVVMDGIT-SPIKADPEWAKT  476
            W  SRQRYWG PIP++  EDGT  + P+ +LP++LP   D+   G   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  T-VNGMPALRETDTFDTFMESSWYYARYTCPEYKEGMLDSEAANYWLPVDIYIGGIEHAI  535
            T  +G+ + RET+T      SSWYY RY  P+  E + D E  + WLPVDIY+GG EHA+
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVER  595
            +HLLY RF HK++ D G+V + EP ++L+ QGM+L+ ++      + R  + + D +  R
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEKR  591

Query  596  DEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMT  655
            D  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D +
Sbjct  592  D--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  656  LEWQESGVEGANRFLKRVWKLVYEHTAKGDVAALNVDALTEDQKALRRDVHKTIAKVTDD  715
            + W E G+EG+ +FL RV +L+   T+K        +   E+  AL +  + T+  VT++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLI---TTK--------EITEENSGALDKVYNETVKAVTEQ  695

Query  716  IGRRQTFNTAIAAIMELMNKLAKAPTDGEQDRALMQEALLAVVRMLNPFTPHICFTLWQE  775
            +++ + FNTAIA +M ++N        ++++  L  +   + V+++ PF+PH+   LWQ 
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  776  LKGEGD-IDNAPWPVADEKAMVEDSTLVVVQVNGKVRAKITVPVDATEEQVRERAGQEHL  834
            L + G+ I   PWP  DE  +VE+   +VVQ++GKV+AK+ V+ D + E+++E A  ++ 
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  835  VAKYLDGVTVRKVIYVPGKLLNLVV  859
            V   + G  + KVI VP KL+N+V+
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVI  832

1190) leuS in NC_017664


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  541 bits (2041),  Expect = 8e-155, Method: Compositional matrix adjust.
 Identities = 361/865 (42%), Positives = 557/865 (65%), Gaps = 46/865 (5%)

Query  5    YRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIA  63
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKTMQRNWIGRSEGVEITFNVNDYDNT  242
            V RK + QW +KITAYA+ LL+DL+ +D WP+++K MQRNWIG+S G ++TF+V+D D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGCTYLAVAAGHPLAQ--KAAENNPELAAFIDECR-NTKVAEAEMATME  299
            +TV+TTRPDT+ G TY  +A+ H+L +   ++++   +A +  +   ++ +A +++A  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGVDTGFKAVHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPV  359
            K GV TG  A++P+ G E+PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L+I PV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  360  ILAADGSEPDLSQQALTEKGVLFNSGEFNGLDHEAAFNAIADKLTAMGVGERKVNYRLRD  419
            +        ++ + A+TE G+ +NS+ ++GLD  +A+  + + L A GVG+ +V YRLRD
Sbjct  362  L-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMVTLEDGTVMPTPDDQLPVILP--EDVVMDGIT-SPIKADPEWAKT  476
            W  SRQRYWG PIP++  EDGT  + P+ +LP++LP   D+   G   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  T-VNGMPALRETDTFDTFMESSWYYARYTCPEYKEGMLDSEAANYWLPVDIYIGGIEHAI  535
            T  +G+ + RET+T      SSWYY RY  P+  E + D E  + WLPVDIY+GG EHA+
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVER  595
            +HLLY RF HK++ D G+V + EP ++L+ QGM+L+ ++      + R  + + D +  R
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEKR  591

Query  596  DEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMT  655
            D  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D +
Sbjct  592  D--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  656  LEWQESGVEGANRFLKRVWKLVYEHTAKGDVAALNVDALTEDQKALRRDVHKTIAKVTDD  715
            + W E G+EG+ +FL RV +L+   T+K        +   E+  AL +  + T+  VT++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLI---TTK--------EITEENSGALDKVYNETVKAVTEQ  695

Query  716  IGRRQTFNTAIAAIMELMNKLAKAPTDGEQDRALMQEALLAVVRMLNPFTPHICFTLWQE  775
            +++ + FNTAIA +M ++N        ++++  L  +   + V+++ PF+PH+   LWQ 
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  776  LKGEGD-IDNAPWPVADEKAMVEDSTLVVVQVNGKVRAKITVPVDATEEQVRERAGQEHL  834
            L + G+ I   PWP  DE  +VE+   +VVQ++GKV+AK+ V+ D + E+++E A  ++ 
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  835  VAKYLDGVTVRKVIYVPGKLLNLVV  859
            V   + G  + KVI VP KL+N+V+
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVI  832

1191) leuS in NC_011740


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  541 bits (2041),  Expect = 8e-155, Method: Compositional matrix adjust.
 Identities = 361/865 (42%), Positives = 557/865 (65%), Gaps = 46/865 (5%)

Query  5    YRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIA  63
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKTMQRNWIGRSEGVEITFNVNDYDNT  242
            V RK + QW +KITAYA+ LL+DL+ +D WP+++K MQRNWIG+S G ++TF+V+D D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGCTYLAVAAGHPLAQ--KAAENNPELAAFIDECR-NTKVAEAEMATME  299
            +TV+TTRPDT+ G TY  +A+ H+L +   ++++   +A +  +   ++ +A +++A  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGVDTGFKAVHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPV  359
            K GV TG  A++P+ G E+PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L+I PV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  360  ILAADGSEPDLSQQALTEKGVLFNSGEFNGLDHEAAFNAIADKLTAMGVGERKVNYRLRD  419
            +        ++ + A+TE G+ +NS+ ++GLD  +A+  + + L A GVG+ +V YRLRD
Sbjct  362  L-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMVTLEDGTVMPTPDDQLPVILP--EDVVMDGIT-SPIKADPEWAKT  476
            W  SRQRYWG PIP++  EDGT  + P+ +LP++LP   D+   G   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  T-VNGMPALRETDTFDTFMESSWYYARYTCPEYKEGMLDSEAANYWLPVDIYIGGIEHAI  535
            T  +G+ + RET+T      SSWYY RY  P+  E + D E  + WLPVDIY+GG EHA+
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVER  595
            +HLLY RF HK++ D G+V + EP ++L+ QGM+L+ ++      + R  + + D +  R
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEKR  591

Query  596  DEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMT  655
            D  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D +
Sbjct  592  D--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  656  LEWQESGVEGANRFLKRVWKLVYEHTAKGDVAALNVDALTEDQKALRRDVHKTIAKVTDD  715
            + W E G+EG+ +FL RV +L+   T+K        +   E+  AL +  + T+  VT++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLI---TTK--------EITEENSGALDKVYNETVKAVTEQ  695

Query  716  IGRRQTFNTAIAAIMELMNKLAKAPTDGEQDRALMQEALLAVVRMLNPFTPHICFTLWQE  775
            +++ + FNTAIA +M ++N        ++++  L  +   + V+++ PF+PH+   LWQ 
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  776  LKGEGD-IDNAPWPVADEKAMVEDSTLVVVQVNGKVRAKITVPVDATEEQVRERAGQEHL  834
            L + G+ I   PWP  DE  +VE+   +VVQ++GKV+AK+ V+ D + E+++E A  ++ 
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  835  VAKYLDGVTVRKVIYVPGKLLNLVV  859
            V   + G  + KVI VP KL+N+V+
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVI  832

1192) Afer_1322 in NC_013124


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  541 bits (2041),  Expect = 8e-155, Method: Compositional matrix adjust.
 Identities = 346/850 (41%), Positives = 535/850 (63%), Gaps = 59/850 (6%)

Query  5    YDPPALERSWQERWDNDETYYVSADDPRPKSYVLCMYPYPSGSA-HQGHVRNYAFGDLNV  63
            YD  A+E  WQ  W +++T+  ++D ++PK Y L M+PYPSG++ H GH   Y+  D+  
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYRTMRGHAVLSPFGFDSFGLPAENAAIKTGVHPRLFTEERIAELKASVKRLGTAYDWRR  123
            R++  +GH VL P G D+FGLPAE+ A+ TG +P  FT E IA++K  ++ LG +YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EIKSHDPSYIRWTQYLFLKLYEAGLAYQADAPVNWCPGCQTVLANEQVLPDGTCERSGDV  183
            E+++ DP+Y +WTQ +F KLYE GLAY+A+ PVNW     T +ANE+VLPDGT ER+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  184  VVRRNLRQWFFAITRYANELLDTLDELAWPERVKVMQRNWIGRSEGAEIDFPLADDPTRS  243
            VVR+ +RQW + IT YA+ LL+ L+E+ WPE +K MQRNWIG+S GA++ F +  D  + 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKV-KDTDKD  242

Query  244  ITVFTTRPDTIFGVTFLVLAPEHPLVESITPPERRDEVEAFRADVATRSELERQSDVASL  303
            +TVFTTRPDT+FG T+ VLAPEH+LV++IT +++ + V  ++ + + +S+L R +D+A  
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLAR-TDLAK-  300

Query  304  DKRGLALGISVRNPITGDEVPVFLADYVLAHYGTGAVMGVPGEDERDFRFATAYGLPVVE  363
            +K G+  G    NP+ G E+PV +ADYVLA YGTGA+M+VP++DERD  FA  + L ++ 
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDII-  359

Query  364  TVTRPSDHPGGAWSGDGTKINSGPFDGLSVAAAKRAVIEALEQQGAGRSRTVYRLRDWLI  423
             V   ++   +A + DG  INS+ +DGL  A+A   ++E LE +G G     YRLRDWL+
Sbjct  360  PVLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLF  419

Query  424  SRQRYWGCPIPIVHCSACGTVPVPEDQLPVLAPDDVEFLP--TGESPLARHAGFVNTTCP  481
            SRQRYWG PIPI+H     + +VPE +LP++ P   ++ P  TGESPLA  ++ ++ T  
Sbjct  420  SRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRE  479

Query  482  QCGGPARRETDTMDTFVDSSWYFLRFCDPFSEDRPFDIAAVEAWMPVDQYIGGIEHAILH  541
            + G  +RRET+TM    +SSWY+LR+ DP + ++  D   +  W+PVD Y+GG EHA+LH
Sbjct  480  D-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLH  538

Query  542  LLYARFFTKALSDLGLIPATLREPFRQLFTQGMIR------------------------F  577
            LLYARF  K L DLG++P+  +EPF++LF QGMI                         F
Sbjct  539  LLYARFWHKVLYDLGVVPT--KEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFF  596

Query  578  H----------GSKMSKSKGNLVTPQQYFDTVGADALRLYHFFVGPPADDVDWTDQTDEI  627
            H           +KMSKS  N+V P++  +  GAD+LR+Y+ F+GP    + W+++    
Sbjct  597  HVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEG---  653

Query  628  IEGCARYLQRVWRLAERIGVTDTPTSAPVANDLAIAIERLTQRVTDAIERWSYNAAVAAL  687
            +EG  ++L+RV RL     +T+  ++A     L    +   + VT+ +++  +N+A+A L
Sbjct  654  LEGSRKFLDRVYRLITTKEITEENSGA-----LDKVYNETVKAVTEQVDQMKFNTAIAQL  708

Query  688  MELANLLGDERLLAQPDLADFGLARLLTMLAPFTPHITAELFE--RRYGRNVHREPWPTV  745
            M + N    E  L    ++D++ + ++ ++APF+PH+  EL +     G ++   PWP+ 
Sbjct  709  MVFVNAANKEDKL----FSDYAKG-FVQLIAPFAPHLGEELWQALTASGESISYVPWPSY  763

Query  746  DHELLASARTTLAVQVNGKLRGTIEVDPSIEESEAIDLARALPSVDAALAGREPERCIVR  805
            D+  L      + VQ++GK+++ + V   +   E  ++A A   V+A +AG++  + I  
Sbjct  764  DESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAV  823

Query  806  LPRIVNFVVR  815
              ++VN+V++
Sbjct  824  PNKLVNIVIK  833

1193) Thivi_0986 in NC_018012


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  541 bits (2042),  Expect = 8e-155, Method: Compositional matrix adjust.
 Identities = 348/864 (41%), Positives = 550/864 (64%), Gaps = 53/864 (6%)

Query  5    YDPRAVETAAQQYWEGHQSFKAVEDPSREKFYCLSMFPYPSGR-LHMGHVRNYTIGDVIA  63
            YD  A+E   Q +W ++++FK+  D+S+ KFY L MFPYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMQGKNVLQPMGWDAFGLPAENAAIQHGIPPSQWTRSNIAYMKDQLKSLGFGYDWAR  123
            R++R QG NVL+PMGWDAFGLPAE+ A++ G  P++ T  NIA  K Q+++LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCDPDYYRWEQWLFTRLMEKGLAYRAKTTVNWDPIDQTVLANEQVI-DGRGWRSGAP  182
            E+ T DP+YY+W QW+FT+L EKGLAY A   VNW     T +ANE+V+ DG + R+G P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VEKREIEQWLVRITDYAQELLDALDGLDGWPERVRIMQRNWIGRSEGVHMDFGIAGSDET  242
            V ++ + QW+++IT YA+ LL+ L+ +D WPE ++ MQRNWIG+S G ++ F + ++D  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LGIYTTRPDTVMGVTYVAVAAEHPLAHRAALDNPEIAAFIEDCRQGGTSEAEIE----TM  298
            + ++TTRPDT+ G TY  +A+EH+L +  A+  ++ A  + D ++ ++  +++     + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVD--AITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  299  EKKGQRLGIDAIHPITGEPVPIFAANFVLMGYGTGAVMAVPAHDQRDWEFAERYGIPKKP  358
            EK G + G  AI+P+ G  +P+  A++VL +YGTGA+MAVPAHD+RDWEFA ++ +   P
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VIRSADDSPCGIEQAAYTDKGVLFNSGPFDGLTSAQAFEAIADWLSERGRGQKTVNFRLR  418
            V+ +++     +E+AA+T+ G+ +NS+ +DGL  A A+  + +WL   G G+  V +RLR
Sbjct  361  VLEGGN-----VEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  419  DWGVSRQRYWGCPIPVVRTADGGTR--PETDLPVRLP--EDVIVDGSG-SPLKKMPSFSE  473
            DW  SRQRYWG PIP+++  DG +   PE++LP+ LP   D+   G+G SPL ++    E
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  474  LPNGEV----RETDTFDTFFESSWYYARYCSAGCDTAMLDAR-ANYWLPVDQYVGGIEHA  528
            +   +     RET+T      SSWYY RY  +     + D    + WLPVD YVGG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  529  VLHLLYARFFHKLMRDEGLVDCDEPFKNLLTQGMVVAETWFREDGEGRKQWFNPSDIESE  588
            VLHLLYARF HK++ D G+V   EPF++L+ QGM+++ + +R+           + + ++
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS-YRDS--------RGALVATD  586

Query  589  RDEKGKLVGAVLKSDGQPVTFGGIEKMSKSKNNGVDPQSLTERYGADTVRLYTMFTSPPD  648
            + EK    G+ +  +       +  KMSKS +N V+P+ + E+YGADT+R+Y MF +P D
Sbjct  587  KVEKRD--GSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLD  644

Query  649  QSLEWNDEGVEGAFRFIKRLWALAVGESESIQSDATLAGELDDANRDARRELHATLNKAL  708
             S+ W++EG+EG+ +F+ R+  L      + ++ ++L    +++ +    ++        
Sbjct  645  ASIAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALDKVYNETVKAVTEQV--------  696

Query  709  FDYERQQFNTVVSACMTMVNTLYRLEPSAARAAIVREGVGIVLRLLAPISPHVTHHLWRE  768
               ++ +FNT ++  M  VN+      +     +  +     ++L+AP++PH+ ++LW+ 
Sbjct  697  ---DQMKFNTAIAQLMVFVNA------ANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  769  L-GFGEDILSAPWPTVDDDALRQDSIEYVVQVNGKVRASVKVPADADRETIQAAALANGQ  827
            L + GE I   PWP+ D+  L ++ +E VVQ++GKV+A + V+ D  RE +Q  ALAN +
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  828  VLKFIGDKAVRKVILVPNKLVNIV  851
            V   I++K + KVI VPNKLVNIV
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIV  831

1194) leuS in NC_014659


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  541 bits (2041),  Expect = 9e-155, Method: Compositional matrix adjust.
 Identities = 355/732 (49%), Positives = 498/732 (69%), Gaps = 53/732 (7%)

Query  225  LVYHSDSMVNWCPGLGTVLANEEVTADGRSERGNFPVFRKHLQQWMMRITAYSDRLVDDL  284
            L Y+++  VNW   LGT +ANEEV +DG SERG +PV RK ++QWM++ITAY++RL++DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  285  EHLDWPEKVKSMQRNWIGRSHGAQVKFD--SNGHDIEVFTTRPDTLFGATYVTLAPEHEL  342
            E++DWPE +K MQRNWIG+S GA+V F     + D+ VFTTRPDTLFGATY  LAPEH L
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  343  VDRLVAAEWPEGVDPRWTGGaatpaeavaayraSIAAKTDLERQE-NKEKTGVFLGVYAV  401
            VD + +++ +E+V                 Y+   + K+DL R +  KEKTGV  G YA+
Sbjct  268  VDAITTSDQAEAVA---------------DYKRQASLKSDLARTDLAKEKTGVWTGSYAI  312

Query  402  NPVNGHKLPVFIADYVLTGYGTGAIMAVPGHDQRDWEFATAFGLDIVEVIKGGDLSEAAF  461
            NPVNG  +PV IADYVL++YGTGAIMAVP+HD+RDWEFA  F LDI+ V+ GG++ EAAF
Sbjct  313  NPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEAAF  372

Query  462  TGDGPLVNSDYLDGLDVADAKKAVIARLEADGVGTGTIQYKLRDWLFARQRYWGEPFPIV  521
            T DG  +NSD+LDGLD A A   ++ +LEA+GVG   + Y+LRDWLF+RQRYWGEP+PI+
Sbjct  373  TEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPII  432

Query  522  YDADGVAHPLPESALPVELPEVEDYAPVsfdpddassepsppLAKATDWVNVELDLGDGL  581
               DG + ++PES LP+ LP   D  P        S+   +PLA+ TDW++V  +  DG+
Sbjct  433  HWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTDWLEVTRE--DGV  482

Query  582  KDYRRDTNVMPQWAGSSWYQLRYIDPTNSEQFVAPENEAYWTGPRPDIHGPGDPGGVDLY  641
            K+ RR+TN MPQWAGSSWY LRYIDP N+E++   E    W               VD+Y
Sbjct  483  KG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWL-------------PVDIY  528

Query  642  VGGVEHAVLHLLYSRFWHKVLFDLGYVSSSEPYRRLYNQGYIQAYAYTDDRGVYVPAAEV  701
            VGG EHAVLHLLY+RFWHKVL+DLG V++ EP+++L+NQG I + +Y D RG  V++  V
Sbjct  529  VGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKV  588

Query  702  TEKDGKFFY--EGAEVKREYGKMGKSLKNSVAPDQICDEFGADTLRVYEMAMGPLDTSRP  759
              +DG FF    G E+ +  +KM+KSLKN V PD++ +++GADTLRVYEM MGPLD+S +
Sbjct  589  EKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIA  648

Query  760  WATKDVIGAHRFLQRAWRVVVDEETGDLRVTDAEPSEDTLRALNKTIAGVAEDYAALRDN  819
            W+  ++ G+++FL+R  R++   E  +      E S    +  N T+ +V+E+   ++ N
Sbjct  649  WSEEGLEGSRKFLDRVYRLITTKEITE------ENSGALDKVYNETVKAVTEQVDQMKFN  702

Query  820  TAVAKLIEYTNHLTKEYPAGAPRSVVEPLALMLGPIAPHLAEELWSRL-GHTESLAHGPF  878
            TA+A+L+ + N   KE            +  +++P+APHL+EELW  L +  ES++  P 
Sbjct  703  TAIAQLMVFVNAANKE--DKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPW  760

Query  879  PTADEKWLVEDTVEYPIQVNGKVRSRINVAADAAREDIEKIALADEKIVALLDGNDPRKV  938
            P+ DE  LVE+ VE  +Q++GKV++++ VA D +RE+++ +ALA+EK+ A + G+D  KV
Sbjct  761  PSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKV  820

Query  939  IVVPGKMVNIVL  950
            I VP K+VNIV+
Sbjct  821  IAVPNKLVNIVI  832


 Score =  134 bits (492),  Expect = 3e-32, Method: Compositional matrix adjust.
 Identities = 75/148 (51%), Positives = 103/148 (70%), Gaps = 11/148 (7%)

Query  28   IEKRWQDLWSERGTFDAPNPVGPLAPTDGSPVPPDKLFVQDMFPYPSGAGLHVGHPLGYI  87
            IE +WQ +W++  TF +           G+  +  K++  DMFPYPSGAGLHVGHP GY 
Sbjct  9    IEPKWQAFWADNHTFKT-----------GTDASKPKFYALDMFPYPSGAGLHVGHPEGYT  57

Query  88   ATDVFARYHRMQGRNVLHTLGYDAFGLPAEQYAVQTGTHPRTTTEANIANMQRQLRRLGL  147
            ATD+++R+ R QG+NVLH +G DAFGLPAEQYA++TG +P   T  NIAN +RQ+  LG+
Sbjct  58   ATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGF  117

Query  148  GHDERRSIATTDVDFYHWTQWIFLQIYN  175
            + D  R + TTD ++Y WTQWIF ++Y+
Sbjct  118  SYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1195) Cwoe_2829 in NC_013739


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  541 bits (2040),  Expect = 9e-155, Method: Compositional matrix adjust.
 Identities = 377/853 (45%), Positives = 539/853 (64%), Gaps = 65/853 (7%)

Query  9    YEPKAIEPKWQQVWADEHTWEVSNEDDGRPPYYVLEMLPYPSGEP-HMGHMKNYALGDAV  67
            Y+  AIEPKWQ  WAD+HT   +  D ++P +Y L+M+PYPSG   H+GH   Y+  D +
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGT-DASKPKFYALDMFPYPSGAGLHVGHPEGYTATDIL  62

Query  68   AHFNRRIGRRVLHPMGYDAFGLPAENNAIRTGVHPRDATAESIASFQRQFREWGISIDWT  127
            ++F+R  G+ VLHPMG DAFGLPAE+ A+ TG +P + TAE+IA+F+RQ+   G+S DW 
Sbjct  63   SRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWD  122

Query  128  REFGTHEPRYYRWTQWLFLQLYERGLAYRKEAAVNWCPNDQTVLANEQVV-DGHCERCGF  186
            RE  T +P YY+WTQW+F +LYE+GLAY  E +VNW  +  T +ANE+V+ DG  ER G+
Sbjct  123  REVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGY  182

Query  187  EVEVRQLVQWFFAITRYADRLLADLDTIQWPEHVKTMQRNWIGRSEGAEVTFRNDDVGID  246
             V  + + QW + IT YA+RLL DL+ ++WPE +K MQRNWIG+S GA+VTF+  D + D
Sbjct  183  PVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  247  YEVFTTRPDTLFGATFFVMAPEHPDVLKLVEGTDREQAVRDYINHALTESKEERGDGDKA  306
            + VFTTRPDTLFGAT+ V+APEH+ ++  +  +D+ +AV DY  +A   S   R D  K 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHA-LVDAITTSDQAEAVADYKRQASLKSDLARTDLAKE  301

Query  307  KTGVALGRTVRNPVNGEEIPMYVADYVLMEYGTGAIMAVPGHDARDHAFATAYDLPIRRV  366
            KTGV  G    NPVNG E+P+ +ADYVL  YGTGAIMAVP+HD RD  FA  ++L I  V
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  367  IASEPGVEDELPYTGDGVLVNSAPQF-DGKPNRAALEEIVAWLHGDGKGQRSINYRLRDW  425
            +  E G  +E ++T DG+ +NS  +F DG  + +A+  +V WL+++G G+ ++ YRLRDW
Sbjct  362  L--EGGNVEEAAFTEDGLHINS--DFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDW  417

Query  426  LVSRQRYWGCPIPIVYCDDCGAVPVPAADLPVELPDVTEYKPRGR--SPLAAAEEWVNTT  483
            L SRQRYWG PIPI+  +D  + +VP ++LP+ LP   + +P G   SPLA   +W++ T
Sbjct  418  LFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT  477

Query  484  CPRCGGAARRETDTMDTFVDSSWYFLRYTDANNDEAAWDRTVADRWMPVDQYIGGVEHAI  543
                G  +RRET+TM    +SSWY+LRY D++N E   D  +  +W+PVD Y+GG EHA+
Sbjct  478  RED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  544  LHLLYARFFTKAFADMGLLGSDEPFQALFTQGMI-------------------TRDG---  581
            LHLLYARF  K + D+G++ + EPFQ LF QGMI                    RDG   
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFF  596

Query  582  ------------AKMSKSKGNVISPSTYVDRYGADTARCYILFIGPPDQDADWSDEGVEG  629
                        AKMSKS  NV++P   V++YGADT R Y +F+GP D    WS+EG+EG
Sbjct  597  HVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEG  656

Query  630  VHRFLARLWRLGDELGAGSCDSPAAGSLSADVAVARKAHWAIEKVTNDVSGRFAFNTAIS  689
             ++FL R+ RL   + +       +G+L        K      K   +  ++  FNTAI+
Sbjct  657  SRKFLDRVYRL---ITTKEITEENSGALD-------KVYNETVKAVTEQVDQMKFNTAIA  706

Query  690  AVMELVNECYRHRESASPEVLRFACATA-ASLVFPFAPHVGSEVYE--LTTGRRVWEEPW  746
             +M +VN   ++      + L    A +   L+ PFAPH+G E+ +   ++G  +   PW
Sbjct  707  QLMVFVNAANKE------DKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPW  760

Query  747  PVADPALLEADTFQLVAQVNGKVRDRITAPSDASKERLEELARAAPNVLAHldgrdvvkv  806
            P  D + L  +  ++V Q++GKV+ ++  + D S+E L+E+A A  +V A++ G+D++KV
Sbjct  761  PSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKV  820

Query  807  ivvpgklvNIVVR  819
            I VP KLVNIV++
Sbjct  821  IAVPNKLVNIVIK  833

1196) leuS in NC_009800


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  540 bits (2039),  Expect = 1e-154, Method: Compositional matrix adjust.
 Identities = 359/865 (42%), Positives = 556/865 (65%), Gaps = 46/865 (5%)

Query  5    YRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIA  63
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKTMQRNWIGRSEGVEITFNVNNYDNT  242
            V RK + QW +KITAYA+ LL+DL+ +D WP+++K MQRNWIG+S G ++TF+V++ D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGCTYLAVAAGHPLAQ--KAAENNPELAAFIDECR-NTKVAEAEMATME  299
            +TV+TTRPDT+ G TY  +A+ H+L +   ++++   +A +  +   ++ +A +++A  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGVDTGFKAVHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPV  359
            K GV TG  A++P+ G E+PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L+I PV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  360  ILAADGSEPDLSQQALTEKGVLFNSGEFNGLDHEAAFNAIADKLTAMGVGERKVNYRLRD  419
            +        ++ + A+TE G+ +NS+ ++GLD  +A+  + + L A GVG+ +V YRLRD
Sbjct  362  L-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMVTLEDGTVMPTPDDQLPVILP--EDVVMDGIT-SPIKADPEWAKT  476
            W  SRQRYWG PIP++  EDGT  + P+ +LP++LP   D+   G   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  T-VNGMPALRETDTFDTFMESSWYYARYTCPQYKEGMLDSKAANYWLPVDIYIGGIEHAI  535
            T  +G+ + RET+T      SSWYY RY  P+  E + D    + WLPVDIY+GG EHA+
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVER  595
            +HLLY RF HK++ D G+V + EP ++L+ QGM+L+ ++      + R  + + D +  R
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEKR  591

Query  596  DEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMT  655
            D  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D +
Sbjct  592  D--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  656  LEWQESGVEGANRFLKRVWKLVYEHTAKGDVATLNVDALTEDQKALRRDVHKTIAKVTDD  715
            + W E G+EG+ +FL RV +L+   T+K        +   E+  AL +  + T+  VT++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLI---TTK--------EITEENSGALDKVYNETVKAVTEQ  695

Query  716  IGRRQTFNTAIAAIMELMNKLAKAPTDGEQDRALMQEALLAVVRMLNPFTPHICFTLWQE  775
            +++ + FNTAIA +M ++N        ++++  L  +   + V+++ PF+PH+   LWQ 
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  776  LKGEGD-IDNAPWPVADEKAMVEDSTLVVVQVNGKVRAKITVPVDATEEQVRERAGQEHL  834
            L + G+ I   PWP  DE  +VE+   +VVQ++GKV+AK+ V+ D + E+++E A  ++ 
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  835  VAKYLDGVTVRKVIYVPGKLLNLVV  859
            V   + G  + KVI VP KL+N+V+
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVI  832

1197) leuS in NC_017644


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  540 bits (2039),  Expect = 1e-154, Method: Compositional matrix adjust.
 Identities = 360/865 (42%), Positives = 556/865 (65%), Gaps = 46/865 (5%)

Query  36   YRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIA  94
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  95   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSR  154
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  155  ELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  213
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  214  VERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKTMQRNWIGRSEGVEITFNVNDYDNT  273
            V RK + QW +KITAYA+ LL+DL+ +D WP+++K MQRNWIG+S G ++TF+V+D D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  274  LTVYTTRPDTFMGCTYLAVAAGHPLAQ--KAAENNPELAAFIDECR-NTKVAEAEMATME  330
            +TV+TTRPDT+ G TY  +A+ H+L +   ++++   +A +  +   ++ +A +++A  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  331  KKGVDTGFKAVHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPV  390
            K GV TG  A++P+ G E+PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L+I PV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  391  ILAADGSEPDLSQQALTEKGVLFNSGEFNGLDHEAAFNAIADKLTAMGVGERKVNYRLRD  450
            +        ++ + A+TE G+ +NS+ ++GLD  +A+  + + L A GVG+ +V YRLRD
Sbjct  362  L-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  451  WGVSRQRYWGAPIPMVTLEDGTVMPTPDDQLPVILP--EDVVMDGIT-SPIKADPEWAKT  507
            W  SRQRYWG PIP++  EDGT  + P+ +LP++LP   D+   G   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  508  T-VNGMPALRETDTFDTFMESSWYYARYTCPEYKEGMLDSKAANYWLPVDIYIGGIEHAI  566
            T  +G+ + RET+T      SSWYY RY  P+  E + D    + WLPVDIY+GG EHA+
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  567  MHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVER  626
            +HLLY RF HK++ D G+V + EP ++L+ QGM+L+ ++      + R  + + D +  R
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEKR  591

Query  627  DEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMT  686
            D  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D +
Sbjct  592  D--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  687  LEWQESGVEGANRFLKRVWKLVYEHTAKGDVAALNVDALTEDQKALRRDVHKTIAKVTDD  746
            + W E G+EG+ +FL RV +L+   T+K        +   E+  AL +  + T+  VT++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLI---TTK--------EITEENSGALDKVYNETVKAVTEQ  695

Query  747  IGRRQTFNTAIAAIMELMNKLAKAPTDGEQDRALMQEALLAVVRMLNPFTPHICFTLWQE  806
            +++ + FNTAIA +M ++N        ++++  L  +   + V+++ PF+PH+   LWQ 
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  807  LKGEGD-IDNAPWPVADEKAMVEDSTLVVVQVNGKVRAKITVPVDATEEQVRERAGQEHL  865
            L + G+ I   PWP  DE  +VE+   +VVQ++GKV+AK+ V+ D + E+++E A  ++ 
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  866  VAKYLDGVTVRKVIYVPGKLLNLVV  890
            V   + G  + KVI VP KL+N+V+
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVI  832

1198) leuS in NC_014623


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  540 bits (2039),  Expect = 1e-154, Method: Compositional matrix adjust.
 Identities = 351/861 (41%), Positives = 545/861 (64%), Gaps = 68/861 (7%)

Query  7    YEPQAIEGKWQTRWEEAGVFRAGMRPGAPKKYILEMLPYPSGK-MHMGHVRNYLIGDVYA  65
            Y+  AIE KWQ+ W +   F++G  ++ PK Y L+M+PYPSG  +H+GH   Y   D+ +
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  66   RYFQMKGYDVLHPMGWDAFGLPAENAAIKDGVHPAVRTQENITSFKEEIRSLGYCYDWAR  125
            R+ + +G +VLHPMGWDAFGLPAE+ A+  G +PA  T ENI++FK +I +LG+ YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  126  EVNTSQPEYYRWNQWFFIQMLERGLVYRRFSKVNWCTGCLTVIANEQV-KDGTCERCDSP  184
            EVNT++P+YY+W QW+F ++ E+GL Y     VNW     T IANE+V  DGT ER + P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  185  VLDKEMPEWAFRITKYSQVLLDGLDTLKEWPERITSMQRNWIGRSEGAEADFAVQGSGEK  244
            V+ K M +W ++IT Y++ LL++L+ + +WPE I  MQRNWIG+S GA+  F V++++  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  245  IRVFTTRIDTVFGCTYVVLAPDHKLVAKVTAPERQAEVSAFVAKMAATSKTDRLAEGAVK  304
            + VFTTR DT+FG TY VLAP+H LV  +T++++   V+ +  + +  S   R   +  K
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEK  302

Query  305  EGVFTGAYALNPFTGQPVPIWIANFVLSDYGTGAVMSVPAHDERDFDFARKYGLPVKPVV  364
             GV TG+YA+NP  G+ +P+WIA++VL+ YGTGA+M+VPAHDERD +FA+++ L + PV 
Sbjct  303  TGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV-  361

Query  365  QPASGEKLPAGEALEAAFTEDGVLSDSGEFSGQASAEARRRLSAKLEAEGRGKATVTYRQ  424
                   L +G+  EAAFTEDG+  +S+ + G   A A  ++   LEAEG G+  VTYR 
Sbjct  362  -------LEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRL  414

Query  425  KDWGFSRQRYWGTPIPIVYCEKCDPDRRGIPVPVEQLPVRLPEIDTQAVLTGKGEPPLAK  484
            +DW FSRQRYWG PIPI+  E    D  + +VP  +LP+ LP +  +   +G GE+PLA+
Sbjct  415  RDWLFSRQRYWGEPIPIIHWE----DGTSTAVPESELPLVLP-VTKDIRPSGTGESPLAN  469

Query  485  VASWVNTTCPRCGGPARREAETMDTFVDSCWYFARYLSPRYAEAPFDAAEARRWLPVDVY  544
            V+ W++ T    G  +RRE++TM    +S WY+ RY+ P+ +E   D    ++WLPVD+Y
Sbjct  470  VTDWLEVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIY  528

Query  545  VGGPEHAVMHLLYFRFWTRVMKELGLSPVDEPVKRLVTQGIVNGS---DGR---------  592
            VGG+EHAV+HLLY RFW +V+ +LG+ P  EP ++L  QG++ G+   D+R         
Sbjct  529  VGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKV  588

Query  593  ---------------------KMSKRWGNVVAPATIVKKYGADTARAYVMFAGPPERDFD  631
                                 KMSK   NVV P  +V +YGADT R Y MF GP +  + 
Sbjct  589  EKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIA  648

Query  632  WSDAQVEGAFRFLKRVWTLAVSHESVAGTVYTGPFEGKALEIRRAAHKCLKRVGEAIERL  691
            WS+  +EG+ +FL RV  L  + E       +G+++       +  +  +K V E ++++
Sbjct  649  WSEEGLEGSRKFLDRVYRLITTKEITEEN--SGALD-------KVYNETVKAVTEQVDQM  699

Query  692  SFNTAIAGIMEYLNALQALGTAETPAEKAAMAEAIRVLAVVLTPFTPHIADEVAEAYGAK  751
             FNTAIA +M ++NA        +  E    ++  + +  +++PF+PH+++E+ +A  A 
Sbjct  700  KFNTAIAQLMVFVNA--------ANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTAS  751

Query  752  AFTVQ-EAWPDFDPALVVDDEIPYAVQVNGKLRAEIKvsaeaseadvravaeadervkaa  810
            + ++   +WP +D + +V++++   VQ++GK++A + V+ + S  +++ VA A+E+V+A 
Sbjct  752  GESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAE  811

Query  811  MAGKALRKFVFVPKRLVNFVV  831
            +AGK + K + VP++LVN+V+
Sbjct  812  IAGKDIIKVIAVPNKLVNIVI  832

1199) Desde_3702 in NC_018017


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  540 bits (2038),  Expect = 2e-154, Method: Compositional matrix adjust.
 Identities = 370/869 (43%), Positives = 552/869 (64%), Gaps = 79/869 (9%)

Query  5    YLFSEIEPKWQKKWVDRKDYKAEDHSDKPKYYALAMFPYPSG-NLHMGHVRNYSIVDVIA  63
            Y  + IEPKWQ  W D   +K+  ++ KPK+YAL MFPYPSG  LH+GH   Y+  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RFKRMSGFNVLHPIGWDSFGLPAENAAIKNQTPPAEWTWKNIANMKGQLQEMGISYDWDR  123
            RFKR  G NVLHP+GWD+FGLPAE+ A+     PAE T  NIAN K Q++ +G+SYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVTTCHPDYYKFTQWVFLEFYKHGLVYKKKAGVNWCPSCATVLANEQVV-DGACERCDTA  182
            EV T +P+YYK TQW+F  +Y  GL Y     VNW    +T +ANE+V+ DG+ ER + +
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VTKKDLEQWFFKITDYAQVLLDDLEKLPGWPEKVKTMQKNWIGRSEGTEVEFSVENHPDK  242
            V +K + QW +KIT YA+ LL+DLE + +WPE +K MQ+NWIG+S G++V F V +    
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  IRVYTTRVDTIFGVSYVVLAPEHPLVQRLVAGTEYEKDVQAFINRMKGLNEIARTSTETE  302
            + V+TTR DT+FG +Y VLAPEH+LV+ + ++ +    V  +  +    +++ART    E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQ-AEAVADYKRQASLKSDLARTDLAKE  301

Query  303  KEGLFTGAYCINPYSGEKVPIWIANYVLFEYGTGAVMGVPAHDERDFEFAKKYKFPIKTV  362
            K G+ TG+Y INP +G  +P+WIA+YVL  YGTGA+M+VPAHDERD EFAK++++ I  V
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  363  ILPEGTPVEEKDTPLQAAFVEEGVMVNSGEYNGLKNMDAWGKMCDKAEQNGFGERKVNFR  422
            +  EG  VEE      AAF E+G+ +NS+  +GL +  A +KM +  E +G G+ +V +R
Sbjct  362  L--EGGNVEE------AAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYR  413

Query  423  LRDWLISRQRYWGAPIPMIYCDHCGIvpvpqdqlpvllpddvvFK---AGENPLTTSESF  479
            LRDWL+SRQRYWG PIP+I  ++    +VP+ +LP++LP    ++   +GE+PL+     
Sbjct  414  LRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDW  473

Query  480  KQTTCPTCGGKAHRETDTMDTFMCSSWYFLRYTDPQNDELPFAKEAADHWMNVDQYVGGV  539
             + T    G K++RET+TM     SSWY+LRY DP+N E     E   +W+ VD YVGG 
Sbjct  474  LEVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGA  532

Query  540  EHAILHLLYSRFFTKALRDFGYLKVDEPFENLLTQGMV----------CL----------  579
            EHA+LHLLY+RF  K L D+G +   EPF++L+ QGM+           L          
Sbjct  533  EHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRD  592

Query  580  --------------GGAKMSKSKGNVVSPEEIISKYGADTARLFILFAAPPERDLEWSDQ  625
                          + AKMSKS  NVV+P++++ +YGADT R++ +F +P +  + WS++
Sbjct  593  GSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEE  652

Query  626  GVEGCYRFLNRVWRLASQYEEVLKEKNSGAGDNGSVYDFGELDKAAKDMRRQTHQTIQRV  685
            G+EG  +FL+RV RL +  E  + E NSGA D+  VY                ++T++ V
Sbjct  653  GLEGSRKFLDRVYRLITTKE--ITEENSGALDK--VY----------------NETVKAV  692

Query  686  TSDVGARFNFNTAVSSIMELVNALYLYKEQPNMNFAVAQEALESILILLGPFAPHITEEI  745
            T +V+ + +FNTA++ +M +VNA     ++ +  F+   +   +++ L++PFAPH+ EE+
Sbjct  693  TEQVD-QMKFNTAIAQLMVFVNA----ANKEDKLFS---DYAKGFVQLIAPFAPHLGEEL  744

Query  746  WSEL-GHEESIHSREWPKVDEGALVQEEVTVVLQINGKLKDRIQVPAQISAAELEAQVRQ  804
            W  L +  ESI    WP  DE+ LV+++V +V+QI+GK+K ++ V+ ++S  EL+     
Sbjct  745  WQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALA  804

Query  805  LPRLGEWTQGKQIVKIVTVPGKLVNVVVK  833
              ++     GK+I+K+++VP KLVN+V+K
Sbjct  805  NEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

1200) leuS in NC_008711


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  540 bits (2038),  Expect = 2e-154, Method: Compositional matrix adjust.
 Identities = 355/855 (42%), Positives = 550/855 (65%), Gaps = 66/855 (7%)

Query  48   YSFAAMEAKWPQVWEDLKVFTPADDGSRERRYVLDMFPYPSG-DLHMGHAEAFAMGDVVA  106
            Y  +A+E+KW   W D   F  + D+S+ + Y LDMFPYPSG +LH+GH+E+++  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  107  RYLRQKGFDVLHPIGWDSFGLPAENAAIKRNAHPSEWTYANIDTQAASFKRYAISADWSR  166
            R+ R +G +VLHP+GWD+FGLPAE+ A+    +P+E T  NI      ++  ++S DW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  167  RLHTSDPEYYRWTQWLFKRFYERGLAYRKDSPVNWCPKDLTVLANEQVV-NGACERCGTP  225
             ++T+DP+YY+WTQW+F ++YE+GLAY  + PVNW     T +ANE+V+ +G+ ER G P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  226  VTKKSLNQWYFKITDYADRLLEDMDQLQGHWPERVLAMQRNWIGRSEGAHVRFVIEATAD  285
            V +K++ QW +KIT YA+RLLED+++++  WPE +  MQRNWIG+S GA+V F +  T  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD--WPESIKDMQRNWIGKSTGANVTFKVKDT--  239

Query  286  RAEREVTVFTTRPDTLYGATFFvvaadahlaldlvTPEQHDELMAYREKVKALSEIERQS  345
              +++ TVFTTRPDTL+GAT+ V+A++  L   + T++Q + +  Y+ +    S++ R  
Sbjct  240  --DKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTD  297

Query  346  TEREKTGVFTGRYAINPLNGEKLPVWAADYVLADYGTGAIMAVPAHDQRDLDFAKTFGLP  405
              +EKTGV TG YAINP+NG  +PVW ADYVLA YGTGAIMAVPAHD+RD +FAK F L 
Sbjct  298  LAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLD  357

Query  406  VRAVLDTGDEDPAETGVATAGEGTLKNSGELDGLSKSEGIPAAIEILEKLGTGEKFVNFR  465
            + +VL+ G+ + A    A + +G   NS+ LDGL K+ +I+  +E LE  G G+  V +R
Sbjct  358  IIPVLEGGNVEEA----AFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYR  413

Query  466  LRDWLLSRQRFWGTPIPIIHCGECGEVPVPDDQLPVRLP--DDLRGEALSPKGTSPLAAA  523
            LRDWL+SRQR+WG PIPIIH  +    +VP+ +LP+ LP   D+R    S  G SPLA  
Sbjct  414  LRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRP---SGTGESPLANV  470

Query  524  VEWVNVECPNCGRAAQRDTDTMDTFVDSSWYFLRFVSPDYTEGPFDPEKINNWMPVGQYV  583
             +W++V   +  + ++R+T+TM    +SSWY+LR++ P+ TE   D E +++W+PV+ YV
Sbjct  471  TDWLEVTREDGVK-GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYV  529

Query  584  GGVEHAILHLLYARFFTKVIKDIGLIEANEPFSALLNQGQVLNGG---------------  628
            GG EHA+LHLLYARF  KV+ D+G++ ++EPF  L+NQG +L  +               
Sbjct  530  GGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVE  589

Query  629  -------------------KAMSKSLGNGVDLGEQLDKFGVDAVRLTMVFASPPEDDVDW  669
                                 MSKSL N V+ ++ ++++G D++R+  +F +P +  + W
Sbjct  590  KRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAW  649

Query  670  ADVSPSGSAKFLARAWRLGQDVSSEPGVDPATGDRALRTVTHKTIADAAELLDNNKFNVV  729
            ++ +  GS KFL R  RL   +++    +  +G  AL  V + T+   +E +D+ KFN  
Sbjct  650  SEEGLEGSRKFLDRVYRL---ITTKEITEENSG--ALDKVYNETVKAVTEQVDQMKFNTA  704

Query  730  VARLMELVNATRKTIDSGAGaadpavreaveavavILSLFAPYTAEDLWNTLGHPA-SVA  788
            +A+LM +VNA+ K         D    +   +   +++ FAP  +E+LW++L  ++ S++
Sbjct  705  IAQLMVFVNAANKE--------DKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESIS  756

Query  789  NAGWPKHDDallvqdtvtavvqvQGKVRDRLEVSPDITEDALRELALASENVQRALDGRG  848
               WP  D++ LV++ V  VVQ++GKV+ +L V+ D++ + L+E+ALA+E+VQ  + G++
Sbjct  757  YVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKD  816

Query  849  IRTVIVRAPKLVNIV  863
            I  VI  + KLVNIV
Sbjct  817  IIKVIAVPNKLVNIV  831

1201) leuS in NC_008253


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  540 bits (2037),  Expect = 2e-154, Method: Compositional matrix adjust.
 Identities = 360/865 (42%), Positives = 556/865 (65%), Gaps = 46/865 (5%)

Query  5    YRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIA  63
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKTMQRNWIGRSEGVEITFNVNDYDNT  242
            V RK + QW +KITAYA+ LL+DL+ +D WP+++K MQRNWIG+S G ++TF+V+D D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGCTYLAVAAGHPLAQ--KAAENNPELAAFIDECR-NTKVAEAEMATME  299
            +TV+TTRPDT+ G TY  +A+ H+L +   ++++   +A +  +   ++ +A +++A  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGVDTGFKAVHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPV  359
            K GV TG  A++P+ G E+PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L+I PV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  360  ILAADGSEPDLSQQALTEKGVLFNSGEFNGLDHEAAFNAIADKLTAMGVGERKVNYRLRD  419
            +        ++ + A+TE G+ +NS+ ++GLD  +A+  + + L A GVG+ +V YRLRD
Sbjct  362  L-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMVTLEDGTVMPTPDDQLPVILP--EDVVMDGIT-SPIKADPEWAKT  476
            W  SRQRYWG PIP++  EDGT  + P+ +LP++LP   D+   G   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  T-VNGMPALRETDTFDTFMESSWYYARYTCPEYKEGMLDSKAANYWLPVDIYIGGIEHAI  535
            T  +G+ + RET+T      SSWYY RY  P+  E + D    + WLPVDIY+GG EHA+
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVER  595
            +HLLY RF HK++ D G+V + EP ++L+ QGM+L+ ++      + R  + + D +  R
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEKR  591

Query  596  DEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMT  655
            D  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D +
Sbjct  592  D--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  656  LEWQESGVEGANRFLKRVWKLVYEHTAKGDVAALNVDALTEDQKALRRDVHKTIAKVTDD  715
            + W E G+EG+ +FL RV +L+   T+K        +   E+  AL +  + T+  VT++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLI---TTK--------EITEENSGALDKVYNETVKAVTEQ  695

Query  716  IGRRQTFNTAIAAIMELMNKLAKAPTDGEQDRALMQEALLAVVRMLNPFTPHICFTLWQE  775
            +++ + FNTAIA +M ++N        ++++  L  +   + V+++ PF+PH+   LWQ 
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  776  LKGEGD-IDNAPWPVADEKAMVEDSTLVVVQVNGKVRAKITVPVDATEEQVRERAGQKHL  834
            L + G+ I   PWP  DE  +VE+   +VVQ++GKV+AK+ V+ D + E+++E A  ++ 
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  835  VAKYLDGVTVRKVIYVPGKLLNLVV  859
            V   + G  + KVI VP KL+N+V+
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVI  832

1202) leuS in NC_017631


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  540 bits (2037),  Expect = 2e-154, Method: Compositional matrix adjust.
 Identities = 360/865 (42%), Positives = 556/865 (65%), Gaps = 46/865 (5%)

Query  5    YRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIA  63
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKTMQRNWIGRSEGVEITFNVNDYDNT  242
            V RK + QW +KITAYA+ LL+DL+ +D WP+++K MQRNWIG+S G ++TF+V+D D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGCTYLAVAAGHPLAQ--KAAENNPELAAFIDECR-NTKVAEAEMATME  299
            +TV+TTRPDT+ G TY  +A+ H+L +   ++++   +A +  +   ++ +A +++A  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGVDTGFKAVHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPV  359
            K GV TG  A++P+ G E+PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L+I PV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  360  ILAADGSEPDLSQQALTEKGVLFNSGEFNGLDHEAAFNAIADKLTAMGVGERKVNYRLRD  419
            +        ++ + A+TE G+ +NS+ ++GLD  +A+  + + L A GVG+ +V YRLRD
Sbjct  362  L-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMVTLEDGTVMPTPDDQLPVILP--EDVVMDGIT-SPIKADPEWAKT  476
            W  SRQRYWG PIP++  EDGT  + P+ +LP++LP   D+   G   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  T-VNGMPALRETDTFDTFMESSWYYARYTCPEYKEGMLDSKAANYWLPVDIYIGGIEHAI  535
            T  +G+ + RET+T      SSWYY RY  P+  E + D    + WLPVDIY+GG EHA+
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVER  595
            +HLLY RF HK++ D G+V + EP ++L+ QGM+L+ ++      + R  + + D +  R
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEKR  591

Query  596  DEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMT  655
            D  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D +
Sbjct  592  D--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  656  LEWQESGVEGANRFLKRVWKLVYEHTAKGDVAALNVDALTEDQKALRRDVHKTIAKVTDD  715
            + W E G+EG+ +FL RV +L+   T+K        +   E+  AL +  + T+  VT++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLI---TTK--------EITEENSGALDKVYNETVKAVTEQ  695

Query  716  IGRRQTFNTAIAAIMELMNKLAKAPTDGEQDRALMQEALLAVVRMLNPFTPHICFTLWQE  775
            +++ + FNTAIA +M ++N        ++++  L  +   + V+++ PF+PH+   LWQ 
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  776  LKGEGD-IDNAPWPVADEKAMVEDSTLVVVQVNGKVRAKITVPVDATEEQVRERAGQEHL  834
            L + G+ I   PWP  DE  +VE+   +VVQ++GKV+AK+ V+ D + E+++E A  ++ 
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  835  VAKYLDGVTVRKVIYVPGKLLNLVV  859
            V   + G  + KVI VP KL+N+V+
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVI  832

1203) leuS in NC_009801


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  540 bits (2038),  Expect = 2e-154, Method: Compositional matrix adjust.
 Identities = 359/865 (42%), Positives = 556/865 (65%), Gaps = 46/865 (5%)

Query  5    YRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIA  63
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKTMQRNWIGRSEGVEITFNVNDYDNT  242
            V RK + QW +KITAYA+ LL+DL+ +D WP+++K MQRNWIG+S G ++TF+V+D D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGCTYLAVAAGHPLAQ--KAAENNPELAAFIDECR-NTKVAEAEMATME  299
            +TV+TTRPDT+ G TY  +A+ H+L +   ++++   +A +  +   ++ +A +++A  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGVDTGFKAVHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPV  359
            K GV TG  A++P+ G E+PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L+I PV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  360  ILAADGSEPDLSQQALTEKGVLFNSGEFNGLDHEAAFNAIADKLTAMGVGERKVNYRLRD  419
            +        ++ + A+TE G+ +NS+ ++GLD  +A+  + + L A GVG+ +V YRLRD
Sbjct  362  L-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMVTLEDGTVMPTPDDQLPVILP--EDVVMDGIT-SPIKADPEWAKT  476
            W  SRQRYWG PIP++  EDGT  + P+ +LP++LP   D+   G   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  T-VNGIPALRETDTFDTFMESSWYYARYTCPEYKEGMLDSKAANYWLPVDIYIGGIEHAI  535
            T  +G+ + RET+T      SSWYY RY  P+  E + D    + WLPVDIY+GG EHA+
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVER  595
            +HLLY RF HK++ D G+V + EP ++L+ QGM+L+ ++      + R  + + D +  R
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEKR  591

Query  596  DEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMT  655
            D  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D +
Sbjct  592  D--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  656  LEWQESGVEGANRFLKRVWKLVYEHTAKGDVAALNVDALTEDQKALRRDVHKTIAKVTDD  715
            + W E G+EG+ +FL RV +L+   T+K        +   E+  AL +  + T+  VT++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLI---TTK--------EITEENSGALDKVYNETVKAVTEQ  695

Query  716  IGRRQTFNTAIAAIMELMNKLAKAPTDGEQDRALMQEALLAVVRMLNPFTPHICFTLWQE  775
            +++ + FNTAIA +M ++N        ++++  L  +   + V+++ PF+PH+   LWQ 
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  776  LKGEGD-IDNAPWPVADEKAMVEDSTLVVVQVNGKVRGKITVPVDATEEQVRERAGQEHL  834
            L + G+ I   PWP  DE  +VE+   +VVQ++GKV++K+ V+ D + E+++E A  ++ 
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  835  VAKYLDGVTVRKVIYVPGKLLNLVV  859
            V   + G  + KVI VP KL+N+V+
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVI  832

1204) leuS in NC_011745


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  540 bits (2037),  Expect = 2e-154, Method: Compositional matrix adjust.
 Identities = 360/865 (42%), Positives = 556/865 (65%), Gaps = 46/865 (5%)

Query  5    YRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIA  63
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKTMQRNWIGRSEGVEITFNVNDYDNT  242
            V RK + QW +KITAYA+ LL+DL+ +D WP+++K MQRNWIG+S G ++TF+V+D D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGCTYLAVAAGHPLAQ--KAAENNPELAAFIDECR-NTKVAEAEMATME  299
            +TV+TTRPDT+ G TY  +A+ H+L +   ++++   +A +  +   ++ +A +++A  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGVDTGFKAVHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPV  359
            K GV TG  A++P+ G E+PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L+I PV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  360  ILAADGSEPDLSQQALTEKGVLFNSGEFNGLDHEAAFNAIADKLTAMGVGERKVNYRLRD  419
            +        ++ + A+TE G+ +NS+ ++GLD  +A+  + + L A GVG+ +V YRLRD
Sbjct  362  L-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMVTLEDGTVMPTPDDQLPVILP--EDVVMDGIT-SPIKADPEWAKT  476
            W  SRQRYWG PIP++  EDGT  + P+ +LP++LP   D+   G   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  T-VNGMPALRETDTFDTFMESSWYYARYTCPEYKEGMLDSKAANYWLPVDIYIGGIEHAI  535
            T  +G+ + RET+T      SSWYY RY  P+  E + D    + WLPVDIY+GG EHA+
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVER  595
            +HLLY RF HK++ D G+V + EP ++L+ QGM+L+ ++      + R  + + D +  R
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEKR  591

Query  596  DEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMT  655
            D  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D +
Sbjct  592  D--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  656  LEWQESGVEGANRFLKRVWKLVYEHTAKGDVAALNVDALTEDQKALRRDVHKTIAKVTDD  715
            + W E G+EG+ +FL RV +L+   T+K        +   E+  AL +  + T+  VT++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLI---TTK--------EITEENSGALDKVYNETVKAVTEQ  695

Query  716  IGRRQTFNTAIAAIMELMNKLAKAPTDGEQDRALMQEALLAVVRMLNPFTPHICFTLWQE  775
            +++ + FNTAIA +M ++N        ++++  L  +   + V+++ PF+PH+   LWQ 
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  776  LKGEGD-IDNAPWPVADEKAMVEDSTLVVVQVNGKVRAKITVPVDATEEQVRERAGQEHL  834
            L + G+ I   PWP  DE  +VE+   +VVQ++GKV+AK+ V+ D + E+++E A  ++ 
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  835  VAKYLDGVTVRKVIYVPGKLLNLVV  859
            V   + G  + KVI VP KL+N+V+
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVI  832

1205) ECSF_0582 in NC_013654


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  540 bits (2037),  Expect = 2e-154, Method: Compositional matrix adjust.
 Identities = 360/865 (42%), Positives = 556/865 (65%), Gaps = 46/865 (5%)

Query  5    YRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIA  63
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKTMQRNWIGRSEGVEITFNVNDYDNT  242
            V RK + QW +KITAYA+ LL+DL+ +D WP+++K MQRNWIG+S G ++TF+V+D D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGCTYLAVAAGHPLAQ--KAAENNPELAAFIDECR-NTKVAEAEMATME  299
            +TV+TTRPDT+ G TY  +A+ H+L +   ++++   +A +  +   ++ +A +++A  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGVDTGFKAVHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPV  359
            K GV TG  A++P+ G E+PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L+I PV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  360  ILAADGSEPDLSQQALTEKGVLFNSGEFNGLDHEAAFNAIADKLTAMGVGERKVNYRLRD  419
            +        ++ + A+TE G+ +NS+ ++GLD  +A+  + + L A GVG+ +V YRLRD
Sbjct  362  L-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMVTLEDGTVMPTPDDQLPVILP--EDVVMDGIT-SPIKADPEWAKT  476
            W  SRQRYWG PIP++  EDGT  + P+ +LP++LP   D+   G   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  T-VNGMPALRETDTFDTFMESSWYYARYTCPEYKEGMLDSKAANYWLPVDIYIGGIEHAI  535
            T  +G+ + RET+T      SSWYY RY  P+  E + D    + WLPVDIY+GG EHA+
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVER  595
            +HLLY RF HK++ D G+V + EP ++L+ QGM+L+ ++      + R  + + D +  R
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEKR  591

Query  596  DEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMT  655
            D  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D +
Sbjct  592  D--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  656  LEWQESGVEGANRFLKRVWKLVYEHTAKGDVAALNVDALTEDQKALRRDVHKTIAKVTDD  715
            + W E G+EG+ +FL RV +L+   T+K        +   E+  AL +  + T+  VT++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLI---TTK--------EITEENSGALDKVYNETVKAVTEQ  695

Query  716  IGRRQTFNTAIAAIMELMNKLAKAPTDGEQDRALMQEALLAVVRMLNPFTPHICFTLWQE  775
            +++ + FNTAIA +M ++N        ++++  L  +   + V+++ PF+PH+   LWQ 
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  776  LKGEGD-IDNAPWPVADEKAMVEDSTLVVVQVNGKVRAKITVPVDATEEQVRERAGQEHL  834
            L + G+ I   PWP  DE  +VE+   +VVQ++GKV+AK+ V+ D + E+++E A  ++ 
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  835  VAKYLDGVTVRKVIYVPGKLLNLVV  859
            V   + G  + KVI VP KL+N+V+
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVI  832

1206) leuS in NC_008258


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  540 bits (2038),  Expect = 2e-154, Method: Compositional matrix adjust.
 Identities = 360/865 (42%), Positives = 558/865 (65%), Gaps = 46/865 (5%)

Query  36   YRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIA  94
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  95   RYQHMLGKNVLQPIGWDAFGLPAEGAAVKHHTAPAPWTYDNIAYMKNQLKMLGFGYDWSR  154
            R+++  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  155  ELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  213
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  214  VERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKTMQRNWIGRSEGVEITFNVNDYDNT  273
            V RK + QW +KITAYA+ LL+DL+ +D WP+++K MQRNWIG+S G ++TF+V+D D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  274  LTVYTTRPDTFMGCTYLAVAAGHPLAQ--KAAENNPELAAFIDECR-NTKVAEAEMATME  330
            +TV+TTRPDT+ G TY  +A+ H+L +   ++++   +A +  +   ++ +A +++A  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  331  KKGVDTGFKAVHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPV  390
            K GV TG  A++P+ G E+PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L+I PV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  391  ILAADGSEPDLSQQALTEKGVLFNSGEFNGLDHEAAFNAIADKLTAMGVGERKVNYRLRD  450
            +        ++ + A+TE G+ +NS+ ++GLD  +A+  + + L A GVG+ +V YRLRD
Sbjct  362  L-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  451  WGVSRQRYWGAPIPMVTLEDGTVMPTPDDQLPVILP--EDVVMDGIT-SPIKADPEWAKT  507
            W  SRQRYWG PIP++  EDGT  + P+ +LP++LP   D+   G   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  508  T-VNGMPALRETDTFDTFMESSWYYARYTCPEYKEGMLDSEAANYWLPVDIYIGGIEHAI  566
            T  +G+ + RET+T      SSWYY RY  P+  E + D E  + WLPVDIY+GG EHA+
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  567  MHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVER  626
            +HLLY RF HK++ D G+V + EP ++L+ QGM+L+ ++      + R  + + D +  R
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEKR  591

Query  627  DEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMT  686
            D  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D +
Sbjct  592  D--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  687  LEWQESGVEGANRFLKRVWKLVYEHTAKGDVAALNVDALTEDQKALRRDVHKTIAKVTDD  746
            + W E G+EG+ +FL RV +L+   T+K        +   E+  AL +  + T+  VT++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLI---TTK--------EITEENSGALDKVYNETVKAVTEQ  695

Query  747  IGRRQTFNTAIAAIMELMNKLAKAPTDGEQDRALMQEALQAVVRMLNPFTPHICFTLWQE  806
            +++ + FNTAIA +M ++N        ++++  L  +  ++ V+++ PF+PH+   LWQ 
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  807  LKGEGD-IDNAPWPVADEKAMVEDSTLVVVQVNGKVRAKITVPVDATEEQVRERAGQEHL  865
            L + G+ I   PWP  DE  +VE+   +VVQ++GKV+AK+ V+ D + E+++E A  ++ 
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  866  VAKYLDGVTVRKVIYVPGKLLNLVV  890
            V   + G  + KVI VP KL+N+V+
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVI  832

1207) CYCME_0797 in NC_021917


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  540 bits (2037),  Expect = 2e-154, Method: Compositional matrix adjust.
 Identities = 344/856 (41%), Positives = 544/856 (64%), Gaps = 71/856 (8%)

Query  5    YQPSLIEKSVQEKWQLTGAFEVTEDTTKEKYYCLSMFPYPSGR-LHMGHVRNYTIGDVVS  63
            Y+ + IE   Q  W    +F    D++K K+Y L MFPYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMKGKNVMQPMGWDAFGLPAENAAMKHGVHPGGWTSDNIDYMRTQLKQLGFGYDWKR  123
            R++R +G NV++PMGWDAFGLPAE+ AM  G +P+  T++NI   + Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVATCNDDYYRWEQWFFTRLLEKDLVYKKTAPLNWCPDCNTVLANEQVI-DGCCWRCDNE  182
            EV T + +YY+W QW+FT+L EK+L Y    P+NW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VEKREISQWFMRITNYADELLSSLKELEGWPEQVRTMQQNWIGRSEGVELSFDIEGSDST  242
            V ++ + QW ++IT YA+ LL  L E++ WPE ++ MQ+NWIG+S G +++F + ++D  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LPVYTTRPDTLMGVTYVAVAAEHPL--ALQAAENNTDIAEFLDQCKtmetseaametmeK  300
            + V+TTRPDTL G TY  +A+EH+L  A+ ++++   +A++  Q         +  + EK
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEK  302

Query  301  KGIDSGLKAIHPLTGETVPIWIANFVLMHYGTGAVMSVPAHDQRDFEFANKYGLAIKQVI  360
             G+ +G  AI+P+ G  +P+WIA++VL  YGTGA+M+VPAHD+RD EFA+++ L I  V+
Sbjct  303  TGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL  362

Query  361  ATDNPGEIDLTKQAYTGKGTLLNSAEFDGLDFQQAFDAIAESLSAKGKGKKTVNFRLRDW  420
              +N  E      A+T  G  +NS  +DGLD   A+  + E L A G G+  V +RLRDW
Sbjct  363  EGGNVEE-----AAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDW  417

Query  421  GISRQRYWGTPVSVIYCDDCGTVPVPDEQLPVILP--KDVSLEGVG-SPLARHEEFINTS  477
             +SRQRYWG P+++I  +D  + +VP+ +LP++LP  KD+   G G SPLA   + ++ +
Sbjct  418  LFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT  477

Query  478  CPTCGQQAKRETDTFDTFMESSWYFARYCCADNDQAMLDER-ANYWLPVDQYIGGIEHAI  536
                G +++RET+T      SSWY+ RY  ++N + + DE   + WLPVD Y+GG EHA+
Sbjct  478  RED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  537  LHLLYSRFYTKLLRDLGLVSCDEPFKNLLTQGMVL-------------------KDGT--  575
            LHLLY+RF  K+L DLG+V+  EPF++L+ QGM+L                   +DG+  
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFF  596

Query  576  -------------KMSKSKGNTVDPQGLIEKYGADTVRLFTMFAAPPEQSLEWSDSAVEG  622
                         KMSKS  N V+P++++E+YGADT+R++ MF +P + S+ WS+ ++EG
Sbjct  597  HVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEG  656

Query  623  SFRFIRRLWRQVKEHVDGGLISGYTVDQLSSEDK-VLRRQVHETLNKVNDDYGRRLTFNT  681
            S +F+ R+ R +            T  +++ E+   L +  +ET++ V ++   ++ FNT
Sbjct  657  SRKFLDRVYRLI------------TTKEITEENSGALDKVYNETVKAVTEQ-VDQMKFNT  703

Query  682  AIAANMELLNSVSKFKAETDASRALLQEALESIVLMLSPIIPHVCDQMWQALGHQDPLID  741
            AIA  M ++N+ +K          L+ +   ++V +++P+ PH+ +++WQAL   +  I 
Sbjct  704  AIAQLMVFVNAANK-------EDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESIS  756

Query  742  -VTWPEFDETALVLDEVQMVVQVNGKLRAKLMVAADASKESIEKLALSEDNVNKFIDGKP  800
             V WP +DE+ LV ++V++VVQ++GK++AKL+VA D S+E ++ +AL++++V+  I GK 
Sbjct  757  YVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKD  816

Query  801  VRKVIIVPKRLVNIVI  816
            + KVI VP++LVNIVI
Sbjct  817  IIKVIAVPNKLVNIVI  832

1208) leuS in NC_017462


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  539 bits (2036),  Expect = 3e-154, Method: Compositional matrix adjust.
 Identities = 353/742 (48%), Positives = 511/742 (69%), Gaps = 68/742 (9%)

Query  224  LVYRSHSMVNWCPGLGTVLANEEVTADGRSERGNFPVFRKNLSQWMMRITAYSDRLIDDL  283
            L Y ++  VNW   LGT +ANEEV +DG SERG +PV RK + QWM++ITAY++RL++DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  284  DALDWPDKVKSMQRNWIGRSRGAEVDFDV--LGHTITVFTTRPDTLFGASYMVLAPEHEL  341
            + +DWP+ +K MQRNWIG+S GA+V F V   +  +TVFTTRPDTLFGA+Y VLAPEH L
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  342  VDALVAAGTNSYDGVDPRWTFEQSCPADAVKAYRASIAAKSDLERQE-NKEKTGVYLGVN  400
            VDA+ +++                  A+AV  Y+   + KSDL R +  KEKTGV  G  
Sbjct  268  VDAITTSD-----------------QAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSY  310

Query  401  AVNPVNGESIPVFIGDYVLTGYGTGAIMAVPAHDTRDYEFATEFGLPIREVVAGGNVAEE  460
            A+NPVNG  +PV I+DYVL++YGTGAIMAVPAHD RD EFA +F L I  V+ GGNV E 
Sbjct  311  AINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEA  370

Query  461  AYTESGVAVNSANDEGLDINGLDKQEAIARVIEWLVDKQKGSEKIQYKLRDWLFARQRYW  520
            A+TE G+ +NS       ++GLDK  AIA+++EWL     G+E++ Y+LRDWLF+RQRYW
Sbjct  371  AFTEDGLHINSDF-----LDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYW  425

Query  521  GEPFPVVYDADGVAHALPESMLPVELPEVEDYKPVSFDPDDADSEPQPPLAKATEWTQVE  580
            GEP+P++   DG + A+PES LP+ LP   D +P         +  ++PLA+ T+W +V 
Sbjct  426  GEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTDWLEVT  477

Query  581  LDLGDGLKTYTRDTNVMPQWAGSSWYQLRYIDPTNNKQFCDIENERYWTGPRGENdlggv  640
             +  DG+K   R+TN MPQWAGSSWY LRYIDP N  ++ D E  + W           V
Sbjct  478  RE--DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLP---------V  525

Query  641  dlyvggvEHAVLHLLYSRFWHKVLFDLGYVTSGEPYRRLFNQGYIQAFAYTDSRGVYVPA  700
            D+YVGG EHAVLHLLY+RFWHKVL+DLG V + EP+++LFNQG I + +Y DSRG  V++
Sbjct  526  DIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVAT  585

Query  701  AEVEEKDGKFFY--QGEEVNQEYGKMGKSLKNAVAPDEICSDFGADTLRVYEMAMGPLDT  758
              VE +DG FF    GEE++Q  +KM+KSLKN V PD++  ++GADTLRVYEM MGPLD+
Sbjct  586  DKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  759  SRPWATKDVIGAHRFLQRLWRLVVSEDDGSVVVTDAGLADDDLKQLHRTIAGMRDDYEGL  818
            S +W+  ++ G+++FL+R+ RL+ + +   +   ++G  D   K  + T+ ++ ++ + +
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLITTKE---ITEENSGALD---KVYNETVKAVTEQVDQM  699

Query  819  RINTVVAKVIEYVNYLTK------NYAKGAPRAAVEPLVIMVAPVAPHIAEELWKRL-GH  871
            ++NT +A+++ +VN   K      +YAKG        +V ++AP APH++EELW+ L + 
Sbjct  700  KFNTAIAQLMVFVNAANKEDKLFSDYAKG--------FVQLIAPFAPHLGEELWQALTAS  751

Query  872  EETITFVAFPDYDEKWLVDDEVEMPIQINGKVRARIMVPADATQDQIVEIALAEPTVQSH  931
             E+I++V+ P YDE  LV+++VE+ +QI+GKV+A+++V+ D +++++ E+ALA+  VQ++
Sbjct  752  GESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAE  811

Query  932  LEGKNLFKQIVVPGRMVNLVIK  953
            + GK+++K I VP ++VN+VIK
Sbjct  812  IAGKDIIKVIAVPNKLVNIVIK  833


 Score =  141 bits (520),  Expect = 2e-34, Method: Compositional matrix adjust.
 Identities = 81/149 (55%), Positives = 106/149 (72%), Gaps = 10/149 (6%)

Query  21   GDIERTWQQFWIDNGTFNAPNPVGDLAVAGQELPEDKLFVQDMFPYPSGAGLHVGHPLGY  80
              IE  WQ FW DN TF++          G + +  K++  DMFPYPSGAGLHVGHP GY
Sbjct  7    TAIEPKWQAFWADNHTFKT----------GTDASKPKFYALDMFPYPSGAGLHVGHPEGY  56

Query  81   IATDVFARFNRMLGKNVLHTLGYDAFGLPAEQYAIQTGTHPRATTMSNIANMQRQLSALG  140
             ATD+++RF+R  G NVLH +G DAFGLPAEQYA++TG +P   T  NIAN +RQ++ALG
Sbjct  57   TATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALG  116

Query  141  LGHDPRRSVATTDPEFYKWTQWIFLQIFN  169
            ++ D  R V TTDP++YKWTQWIF ++++
Sbjct  117  FSYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1209) leuS in NC_017306


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  539 bits (2036),  Expect = 3e-154, Method: Compositional matrix adjust.
 Identities = 353/742 (48%), Positives = 511/742 (69%), Gaps = 68/742 (9%)

Query  224  LVYRSHSMVNWCPGLGTVLANEEVTADGRSERGNFPVFRKNLSQWMMRITAYSDRLIDDL  283
            L Y ++  VNW   LGT +ANEEV +DG SERG +PV RK + QWM++ITAY++RL++DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  284  DALDWPDKVKSMQRNWIGRSRGAEVDFDV--LGHTITVFTTRPDTLFGASYMVLAPEHEL  341
            + +DWP+ +K MQRNWIG+S GA+V F V   +  +TVFTTRPDTLFGA+Y VLAPEH L
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  342  VDALVAAGTNSYDGVDPRWTFEQSCPADAVKAYRASIAAKSDLERQE-NKEKTGVYLGVN  400
            VDA+ +++                  A+AV  Y+   + KSDL R +  KEKTGV  G  
Sbjct  268  VDAITTSD-----------------QAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSY  310

Query  401  AVNPVNGESIPVFIGDYVLTGYGTGAIMAVPAHDTRDYEFATEFGLPIREVVAGGNVAEE  460
            A+NPVNG  +PV I+DYVL++YGTGAIMAVPAHD RD EFA +F L I  V+ GGNV E 
Sbjct  311  AINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEA  370

Query  461  AYTESGVAVNSANDEGLDINGLDKQEAIARVIEWLVDKQKGSEKIQYKLRDWLFARQRYW  520
            A+TE G+ +NS       ++GLDK  AIA+++EWL     G+E++ Y+LRDWLF+RQRYW
Sbjct  371  AFTEDGLHINSDF-----LDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYW  425

Query  521  GEPFPVVYDADGVAHALPESMLPVELPEVEDYKPVSFDPDDADSEPQPPLAKATEWTQVE  580
            GEP+P++   DG + A+PES LP+ LP   D +P         +  ++PLA+ T+W +V 
Sbjct  426  GEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTDWLEVT  477

Query  581  LDLGDGLKTYTRDTNVMPQWAGSSWYQLRYIDPTNNKQFCDIENERYWTGPRGENdlggv  640
             +  DG+K   R+TN MPQWAGSSWY LRYIDP N  ++ D E  + W           V
Sbjct  478  RE--DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLP---------V  525

Query  641  dlyvggvEHAVLHLLYSRFWHKVLFDLGYVTSGEPYRRLFNQGYIQAFAYTDSRGVYVPA  700
            D+YVGG EHAVLHLLY+RFWHKVL+DLG V + EP+++LFNQG I + +Y DSRG  V++
Sbjct  526  DIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVAT  585

Query  701  AEVEEKDGKFFY--QGEEVNQEYGKMGKSLKNAVAPDEICSDFGADTLRVYEMAMGPLDT  758
              VE +DG FF    GEE++Q  +KM+KSLKN V PD++  ++GADTLRVYEM MGPLD+
Sbjct  586  DKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  759  SRPWATKDVIGAHRFLQRLWRLVVSEDDGSVVVTDAGLADDDLKQLHRTIAGMRDDYEGL  818
            S +W+  ++ G+++FL+R+ RL+ + +   +   ++G  D   K  + T+ ++ ++ + +
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLITTKE---ITEENSGALD---KVYNETVKAVTEQVDQM  699

Query  819  RINTVVAKVIEYVNYLTK------NYAKGAPRAAVEPLVIMVAPVAPHIAEELWKRL-GH  871
            ++NT +A+++ +VN   K      +YAKG        +V ++AP APH++EELW+ L + 
Sbjct  700  KFNTAIAQLMVFVNAANKEDKLFSDYAKG--------FVQLIAPFAPHLGEELWQALTAS  751

Query  872  EETITFVAFPDYDEKWLVDDEVEMPIQINGKVRARIMVPADATQDQIVEIALAEPTVQSH  931
             E+I++V+ P YDE  LV+++VE+ +QI+GKV+A+++V+ D +++++ E+ALA+  VQ++
Sbjct  752  GESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAE  811

Query  932  LEGKNLFKQIVVPGRMVNLVIK  953
            + GK+++K I VP ++VN+VIK
Sbjct  812  IAGKDIIKVIAVPNKLVNIVIK  833


 Score =  141 bits (520),  Expect = 2e-34, Method: Compositional matrix adjust.
 Identities = 81/149 (55%), Positives = 106/149 (72%), Gaps = 10/149 (6%)

Query  21   GDIERTWQQFWIDNGTFNAPNPVGDLAVAGQELPEDKLFVQDMFPYPSGAGLHVGHPLGY  80
              IE  WQ FW DN TF++          G + +  K++  DMFPYPSGAGLHVGHP GY
Sbjct  7    TAIEPKWQAFWADNHTFKT----------GTDASKPKFYALDMFPYPSGAGLHVGHPEGY  56

Query  81   IATDVFARFNRMLGKNVLHTLGYDAFGLPAEQYAIQTGTHPRATTMSNIANMQRQLSALG  140
             ATD+++RF+R  G NVLH +G DAFGLPAEQYA++TG +P   T  NIAN +RQ++ALG
Sbjct  57   TATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALG  116

Query  141  LGHDPRRSVATTDPEFYKWTQWIFLQIFN  169
            ++ D  R V TTDP++YKWTQWIF ++++
Sbjct  117  FSYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1210) leuS in NC_017301


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  539 bits (2036),  Expect = 3e-154, Method: Compositional matrix adjust.
 Identities = 353/742 (48%), Positives = 511/742 (69%), Gaps = 68/742 (9%)

Query  224  LVYRSHSMVNWCPGLGTVLANEEVTADGRSERGNFPVFRKNLSQWMMRITAYSDRLIDDL  283
            L Y ++  VNW   LGT +ANEEV +DG SERG +PV RK + QWM++ITAY++RL++DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  284  DALDWPDKVKSMQRNWIGRSRGAEVDFDV--LGHTITVFTTRPDTLFGASYMVLAPEHEL  341
            + +DWP+ +K MQRNWIG+S GA+V F V   +  +TVFTTRPDTLFGA+Y VLAPEH L
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  342  VDALVAAGTNSYDGVDPRWTFEQSCPADAVKAYRASIAAKSDLERQE-NKEKTGVYLGVN  400
            VDA+ +++                  A+AV  Y+   + KSDL R +  KEKTGV  G  
Sbjct  268  VDAITTSD-----------------QAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSY  310

Query  401  AVNPVNGESIPVFIGDYVLTGYGTGAIMAVPAHDTRDYEFATEFGLPIREVVAGGNVAEE  460
            A+NPVNG  +PV I+DYVL++YGTGAIMAVPAHD RD EFA +F L I  V+ GGNV E 
Sbjct  311  AINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEA  370

Query  461  AYTESGVAVNSANDEGLDINGLDKQEAIARVIEWLVDKQKGSEKIQYKLRDWLFARQRYW  520
            A+TE G+ +NS       ++GLDK  AIA+++EWL     G+E++ Y+LRDWLF+RQRYW
Sbjct  371  AFTEDGLHINSDF-----LDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYW  425

Query  521  GEPFPVVYDADGVAHALPESMLPVELPEVEDYKPVSFDPDDADSEPQPPLAKATEWTQVE  580
            GEP+P++   DG + A+PES LP+ LP   D +P         +  ++PLA+ T+W +V 
Sbjct  426  GEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTDWLEVT  477

Query  581  LDLGDGLKTYTRDTNVMPQWAGSSWYQLRYIDPTNNKQFCDIENERYWTGPRGENdlggv  640
             +  DG+K   R+TN MPQWAGSSWY LRYIDP N  ++ D E  + W           V
Sbjct  478  RE--DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLP---------V  525

Query  641  dlyvggvEHAVLHLLYSRFWHKVLFDLGYVTSGEPYRRLFNQGYIQAFAYTDSRGVYVPA  700
            D+YVGG EHAVLHLLY+RFWHKVL+DLG V + EP+++LFNQG I + +Y DSRG  V++
Sbjct  526  DIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVAT  585

Query  701  AEVEEKDGKFFY--QGEEVNQEYGKMGKSLKNAVAPDEICSDFGADTLRVYEMAMGPLDT  758
              VE +DG FF    GEE++Q  +KM+KSLKN V PD++  ++GADTLRVYEM MGPLD+
Sbjct  586  DKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  759  SRPWATKDVIGAHRFLQRLWRLVVSEDDGSVVVTDAGLADDDLKQLHRTIAGMRDDYEGL  818
            S +W+  ++ G+++FL+R+ RL+ + +   +   ++G  D   K  + T+ ++ ++ + +
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLITTKE---ITEENSGALD---KVYNETVKAVTEQVDQM  699

Query  819  RINTVVAKVIEYVNYLTK------NYAKGAPRAAVEPLVIMVAPVAPHIAEELWKRL-GH  871
            ++NT +A+++ +VN   K      +YAKG        +V ++AP APH++EELW+ L + 
Sbjct  700  KFNTAIAQLMVFVNAANKEDKLFSDYAKG--------FVQLIAPFAPHLGEELWQALTAS  751

Query  872  EETITFVAFPDYDEKWLVDDEVEMPIQINGKVRARIMVPADATQDQIVEIALAEPTVQSH  931
             E+I++V+ P YDE  LV+++VE+ +QI+GKV+A+++V+ D +++++ E+ALA+  VQ++
Sbjct  752  GESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAE  811

Query  932  LEGKNLFKQIVVPGRMVNLVIK  953
            + GK+++K I VP ++VN+VIK
Sbjct  812  IAGKDIIKVIAVPNKLVNIVIK  833


 Score =  141 bits (520),  Expect = 2e-34, Method: Compositional matrix adjust.
 Identities = 81/149 (55%), Positives = 106/149 (72%), Gaps = 10/149 (6%)

Query  21   GDIERTWQQFWIDNGTFNAPNPVGDLAVAGQELPEDKLFVQDMFPYPSGAGLHVGHPLGY  80
              IE  WQ FW DN TF++          G + +  K++  DMFPYPSGAGLHVGHP GY
Sbjct  7    TAIEPKWQAFWADNHTFKT----------GTDASKPKFYALDMFPYPSGAGLHVGHPEGY  56

Query  81   IATDVFARFNRMLGKNVLHTLGYDAFGLPAEQYAIQTGTHPRATTMSNIANMQRQLSALG  140
             ATD+++RF+R  G NVLH +G DAFGLPAEQYA++TG +P   T  NIAN +RQ++ALG
Sbjct  57   TATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALG  116

Query  141  LGHDPRRSVATTDPEFYKWTQWIFLQIFN  169
            ++ D  R V TTDP++YKWTQWIF ++++
Sbjct  117  FSYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1211) leuS in NC_017303


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  539 bits (2036),  Expect = 3e-154, Method: Compositional matrix adjust.
 Identities = 353/742 (48%), Positives = 511/742 (69%), Gaps = 68/742 (9%)

Query  224  LVYRSHSMVNWCPGLGTVLANEEVTADGRSERGNFPVFRKNLSQWMMRITAYSDRLIDDL  283
            L Y ++  VNW   LGT +ANEEV +DG SERG +PV RK + QWM++ITAY++RL++DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  284  DALDWPDKVKSMQRNWIGRSRGAEVDFDV--LGHTITVFTTRPDTLFGASYMVLAPEHEL  341
            + +DWP+ +K MQRNWIG+S GA+V F V   +  +TVFTTRPDTLFGA+Y VLAPEH L
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  342  VDALVAAGTNSYDGVDPRWTFEQSCPADAVKAYRASIAAKSDLERQE-NKEKTGVYLGVN  400
            VDA+ +++                  A+AV  Y+   + KSDL R +  KEKTGV  G  
Sbjct  268  VDAITTSD-----------------QAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSY  310

Query  401  AVNPVNGESIPVFIGDYVLTGYGTGAIMAVPAHDTRDYEFATEFGLPIREVVAGGNVAEE  460
            A+NPVNG  +PV I+DYVL++YGTGAIMAVPAHD RD EFA +F L I  V+ GGNV E 
Sbjct  311  AINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEA  370

Query  461  AYTESGVAVNSANDEGLDINGLDKQEAIARVIEWLVDKQKGSEKIQYKLRDWLFARQRYW  520
            A+TE G+ +NS       ++GLDK  AIA+++EWL     G+E++ Y+LRDWLF+RQRYW
Sbjct  371  AFTEDGLHINSDF-----LDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYW  425

Query  521  GEPFPVVYDADGVAHALPESMLPVELPEVEDYKPVSFDPDDADSEPQPPLAKATEWTQVE  580
            GEP+P++   DG + A+PES LP+ LP   D +P         +  ++PLA+ T+W +V 
Sbjct  426  GEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTDWLEVT  477

Query  581  LDLGDGLKTYTRDTNVMPQWAGSSWYQLRYIDPTNNKQFCDIENERYWTGPRGENdlggv  640
             +  DG+K   R+TN MPQWAGSSWY LRYIDP N  ++ D E  + W           V
Sbjct  478  RE--DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLP---------V  525

Query  641  dlyvggvEHAVLHLLYSRFWHKVLFDLGYVTSGEPYRRLFNQGYIQAFAYTDSRGVYVPA  700
            D+YVGG EHAVLHLLY+RFWHKVL+DLG V + EP+++LFNQG I + +Y DSRG  V++
Sbjct  526  DIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVAT  585

Query  701  AEVEEKDGKFFY--QGEEVNQEYGKMGKSLKNAVAPDEICSDFGADTLRVYEMAMGPLDT  758
              VE +DG FF    GEE++Q  +KM+KSLKN V PD++  ++GADTLRVYEM MGPLD+
Sbjct  586  DKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  759  SRPWATKDVIGAHRFLQRLWRLVVSEDDGSVVVTDAGLADDDLKQLHRTIAGMRDDYEGL  818
            S +W+  ++ G+++FL+R+ RL+ + +   +   ++G  D   K  + T+ ++ ++ + +
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLITTKE---ITEENSGALD---KVYNETVKAVTEQVDQM  699

Query  819  RINTVVAKVIEYVNYLTK------NYAKGAPRAAVEPLVIMVAPVAPHIAEELWKRL-GH  871
            ++NT +A+++ +VN   K      +YAKG        +V ++AP APH++EELW+ L + 
Sbjct  700  KFNTAIAQLMVFVNAANKEDKLFSDYAKG--------FVQLIAPFAPHLGEELWQALTAS  751

Query  872  EETITFVAFPDYDEKWLVDDEVEMPIQINGKVRARIMVPADATQDQIVEIALAEPTVQSH  931
             E+I++V+ P YDE  LV+++VE+ +QI+GKV+A+++V+ D +++++ E+ALA+  VQ++
Sbjct  752  GESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAE  811

Query  932  LEGKNLFKQIVVPGRMVNLVIK  953
            + GK+++K I VP ++VN+VIK
Sbjct  812  IAGKDIIKVIAVPNKLVNIVIK  833


 Score =  141 bits (520),  Expect = 2e-34, Method: Compositional matrix adjust.
 Identities = 81/149 (55%), Positives = 106/149 (72%), Gaps = 10/149 (6%)

Query  21   GDIERTWQQFWIDNGTFNAPNPVGDLAVAGQELPEDKLFVQDMFPYPSGAGLHVGHPLGY  80
              IE  WQ FW DN TF++          G + +  K++  DMFPYPSGAGLHVGHP GY
Sbjct  7    TAIEPKWQAFWADNHTFKT----------GTDASKPKFYALDMFPYPSGAGLHVGHPEGY  56

Query  81   IATDVFARFNRMLGKNVLHTLGYDAFGLPAEQYAIQTGTHPRATTMSNIANMQRQLSALG  140
             ATD+++RF+R  G NVLH +G DAFGLPAEQYA++TG +P   T  NIAN +RQ++ALG
Sbjct  57   TATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALG  116

Query  141  LGHDPRRSVATTDPEFYKWTQWIFLQIFN  169
            ++ D  R V TTDP++YKWTQWIF ++++
Sbjct  117  FSYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1212) leuS in NC_017031


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  539 bits (2036),  Expect = 3e-154, Method: Compositional matrix adjust.
 Identities = 353/742 (48%), Positives = 511/742 (69%), Gaps = 68/742 (9%)

Query  224  LVYRSHSMVNWCPGLGTVLANEEVTADGRSERGNFPVFRKNLSQWMMRITAYSDRLIDDL  283
            L Y ++  VNW   LGT +ANEEV +DG SERG +PV RK + QWM++ITAY++RL++DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  284  DALDWPDKVKSMQRNWIGRSRGAEVDFDV--LGHTITVFTTRPDTLFGASYMVLAPEHEL  341
            + +DWP+ +K MQRNWIG+S GA+V F V   +  +TVFTTRPDTLFGA+Y VLAPEH L
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  342  VDALVAAGTNSYDGVDPRWTFEQSCPADAVKAYRASIAAKSDLERQE-NKEKTGVYLGVN  400
            VDA+ +++                  A+AV  Y+   + KSDL R +  KEKTGV  G  
Sbjct  268  VDAITTSD-----------------QAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSY  310

Query  401  AVNPVNGESIPVFIGDYVLTGYGTGAIMAVPAHDTRDYEFATEFGLPIREVVAGGNVAEE  460
            A+NPVNG  +PV I+DYVL++YGTGAIMAVPAHD RD EFA +F L I  V+ GGNV E 
Sbjct  311  AINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEA  370

Query  461  AYTESGVAVNSANDEGLDINGLDKQEAIARVIEWLVDKQKGSEKIQYKLRDWLFARQRYW  520
            A+TE G+ +NS       ++GLDK  AIA+++EWL     G+E++ Y+LRDWLF+RQRYW
Sbjct  371  AFTEDGLHINSDF-----LDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYW  425

Query  521  GEPFPVVYDADGVAHALPESMLPVELPEVEDYKPVSFDPDDADSEPQPPLAKATEWTQVE  580
            GEP+P++   DG + A+PES LP+ LP   D +P         +  ++PLA+ T+W +V 
Sbjct  426  GEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTDWLEVT  477

Query  581  LDLGDGLKTYTRDTNVMPQWAGSSWYQLRYIDPTNNKQFCDIENERYWTGPRGENdlggv  640
             +  DG+K   R+TN MPQWAGSSWY LRYIDP N  ++ D E  + W           V
Sbjct  478  RE--DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLP---------V  525

Query  641  dlyvggvEHAVLHLLYSRFWHKVLFDLGYVTSGEPYRRLFNQGYIQAFAYTDSRGVYVPA  700
            D+YVGG EHAVLHLLY+RFWHKVL+DLG V + EP+++LFNQG I + +Y DSRG  V++
Sbjct  526  DIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVAT  585

Query  701  AEVEEKDGKFFY--QGEEVNQEYGKMGKSLKNAVAPDEICSDFGADTLRVYEMAMGPLDT  758
              VE +DG FF    GEE++Q  +KM+KSLKN V PD++  ++GADTLRVYEM MGPLD+
Sbjct  586  DKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  759  SRPWATKDVIGAHRFLQRLWRLVVSEDDGSVVVTDAGLADDDLKQLHRTIAGMRDDYEGL  818
            S +W+  ++ G+++FL+R+ RL+ + +   +   ++G  D   K  + T+ ++ ++ + +
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLITTKE---ITEENSGALD---KVYNETVKAVTEQVDQM  699

Query  819  RINTVVAKVIEYVNYLTK------NYAKGAPRAAVEPLVIMVAPVAPHIAEELWKRL-GH  871
            ++NT +A+++ +VN   K      +YAKG        +V ++AP APH++EELW+ L + 
Sbjct  700  KFNTAIAQLMVFVNAANKEDKLFSDYAKG--------FVQLIAPFAPHLGEELWQALTAS  751

Query  872  EETITFVAFPDYDEKWLVDDEVEMPIQINGKVRARIMVPADATQDQIVEIALAEPTVQSH  931
             E+I++V+ P YDE  LV+++VE+ +QI+GKV+A+++V+ D +++++ E+ALA+  VQ++
Sbjct  752  GESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAE  811

Query  932  LEGKNLFKQIVVPGRMVNLVIK  953
            + GK+++K I VP ++VN+VIK
Sbjct  812  IAGKDIIKVIAVPNKLVNIVIK  833


 Score =  141 bits (520),  Expect = 2e-34, Method: Compositional matrix adjust.
 Identities = 81/149 (55%), Positives = 106/149 (72%), Gaps = 10/149 (6%)

Query  21   GDIERTWQQFWIDNGTFNAPNPVGDLAVAGQELPEDKLFVQDMFPYPSGAGLHVGHPLGY  80
              IE  WQ FW DN TF++          G + +  K++  DMFPYPSGAGLHVGHP GY
Sbjct  7    TAIEPKWQAFWADNHTFKT----------GTDASKPKFYALDMFPYPSGAGLHVGHPEGY  56

Query  81   IATDVFARFNRMLGKNVLHTLGYDAFGLPAEQYAIQTGTHPRATTMSNIANMQRQLSALG  140
             ATD+++RF+R  G NVLH +G DAFGLPAEQYA++TG +P   T  NIAN +RQ++ALG
Sbjct  57   TATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALG  116

Query  141  LGHDPRRSVATTDPEFYKWTQWIFLQIFN  169
            ++ D  R V TTDP++YKWTQWIF ++++
Sbjct  117  FSYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1213) leuS in NC_017305


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  539 bits (2036),  Expect = 3e-154, Method: Compositional matrix adjust.
 Identities = 353/742 (48%), Positives = 511/742 (69%), Gaps = 68/742 (9%)

Query  224  LVYRSHSMVNWCPGLGTVLANEEVTADGRSERGNFPVFRKNLSQWMMRITAYSDRLIDDL  283
            L Y ++  VNW   LGT +ANEEV +DG SERG +PV RK + QWM++ITAY++RL++DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  284  DALDWPDKVKSMQRNWIGRSRGAEVDFDV--LGHTITVFTTRPDTLFGASYMVLAPEHEL  341
            + +DWP+ +K MQRNWIG+S GA+V F V   +  +TVFTTRPDTLFGA+Y VLAPEH L
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  342  VDALVAAGTNSYDGVDPRWTFEQSCPADAVKAYRASIAAKSDLERQE-NKEKTGVYLGVN  400
            VDA+ +++                  A+AV  Y+   + KSDL R +  KEKTGV  G  
Sbjct  268  VDAITTSD-----------------QAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSY  310

Query  401  AVNPVNGESIPVFIGDYVLTGYGTGAIMAVPAHDTRDYEFATEFGLPIREVVAGGNVAEE  460
            A+NPVNG  +PV I+DYVL++YGTGAIMAVPAHD RD EFA +F L I  V+ GGNV E 
Sbjct  311  AINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEA  370

Query  461  AYTESGVAVNSANDEGLDINGLDKQEAIARVIEWLVDKQKGSEKIQYKLRDWLFARQRYW  520
            A+TE G+ +NS       ++GLDK  AIA+++EWL     G+E++ Y+LRDWLF+RQRYW
Sbjct  371  AFTEDGLHINSDF-----LDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYW  425

Query  521  GEPFPVVYDADGVAHALPESMLPVELPEVEDYKPVSFDPDDADSEPQPPLAKATEWTQVE  580
            GEP+P++   DG + A+PES LP+ LP   D +P         +  ++PLA+ T+W +V 
Sbjct  426  GEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTDWLEVT  477

Query  581  LDLGDGLKTYTRDTNVMPQWAGSSWYQLRYIDPTNNKQFCDIENERYWTGPRGENdlggv  640
             +  DG+K   R+TN MPQWAGSSWY LRYIDP N  ++ D E  + W           V
Sbjct  478  RE--DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLP---------V  525

Query  641  dlyvggvEHAVLHLLYSRFWHKVLFDLGYVTSGEPYRRLFNQGYIQAFAYTDSRGVYVPA  700
            D+YVGG EHAVLHLLY+RFWHKVL+DLG V + EP+++LFNQG I + +Y DSRG  V++
Sbjct  526  DIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVAT  585

Query  701  AEVEEKDGKFFY--QGEEVNQEYGKMGKSLKNAVAPDEICSDFGADTLRVYEMAMGPLDT  758
              VE +DG FF    GEE++Q  +KM+KSLKN V PD++  ++GADTLRVYEM MGPLD+
Sbjct  586  DKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  759  SRPWATKDVIGAHRFLQRLWRLVVSEDDGSVVVTDAGLADDDLKQLHRTIAGMRDDYEGL  818
            S +W+  ++ G+++FL+R+ RL+ + +   +   ++G  D   K  + T+ ++ ++ + +
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLITTKE---ITEENSGALD---KVYNETVKAVTEQVDQM  699

Query  819  RINTVVAKVIEYVNYLTK------NYAKGAPRAAVEPLVIMVAPVAPHIAEELWKRL-GH  871
            ++NT +A+++ +VN   K      +YAKG        +V ++AP APH++EELW+ L + 
Sbjct  700  KFNTAIAQLMVFVNAANKEDKLFSDYAKG--------FVQLIAPFAPHLGEELWQALTAS  751

Query  872  EETITFVAFPDYDEKWLVDDEVEMPIQINGKVRARIMVPADATQDQIVEIALAEPTVQSH  931
             E+I++V+ P YDE  LV+++VE+ +QI+GKV+A+++V+ D +++++ E+ALA+  VQ++
Sbjct  752  GESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAE  811

Query  932  LEGKNLFKQIVVPGRMVNLVIK  953
            + GK+++K I VP ++VN+VIK
Sbjct  812  IAGKDIIKVIAVPNKLVNIVIK  833


 Score =  141 bits (520),  Expect = 2e-34, Method: Compositional matrix adjust.
 Identities = 81/149 (55%), Positives = 106/149 (72%), Gaps = 10/149 (6%)

Query  21   GDIERTWQQFWIDNGTFNAPNPVGDLAVAGQELPEDKLFVQDMFPYPSGAGLHVGHPLGY  80
              IE  WQ FW DN TF++          G + +  K++  DMFPYPSGAGLHVGHP GY
Sbjct  7    TAIEPKWQAFWADNHTFKT----------GTDASKPKFYALDMFPYPSGAGLHVGHPEGY  56

Query  81   IATDVFARFNRMLGKNVLHTLGYDAFGLPAEQYAIQTGTHPRATTMSNIANMQRQLSALG  140
             ATD+++RF+R  G NVLH +G DAFGLPAEQYA++TG +P   T  NIAN +RQ++ALG
Sbjct  57   TATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALG  116

Query  141  LGHDPRRSVATTDPEFYKWTQWIFLQIFN  169
            ++ D  R V TTDP++YKWTQWIF ++++
Sbjct  117  FSYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1214) Btus_1210 in NC_014098


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  539 bits (2034),  Expect = 3e-154, Method: Compositional matrix adjust.
 Identities = 365/829 (45%), Positives = 522/829 (63%), Gaps = 62/829 (7%)

Query  15   YVPAEIEPKWQNLWEETGLYRTREDANRPHYYCLEMFPYPSGK-LHMGHVRVYSIGDVVA  73
            Y  + IEPKWQ +W +   ++T  DA++P +Y L+MFPYPSG  LH+GH   Y+  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  74   RVKRMQGYNVLHPMGWDAFGMPAENAAIQHGVHPRLWTYENIDHMRQQQKRLGVSYDWER  133
            R KR QG NVLHPMGWDAFG+PAE+ A++ G +P   T ENI + ++Q + LG SYDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  134  EVTTCAPDYYKFTQWMFLLFYHRGLAYRKKAAVNWCPHCVTVLANEQV-ENGRCWRCGTE  192
            EV T  P+YYK TQW+F  +Y++GLAY    +VNW  +  T +ANE+V  +G   R G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  193  VTKRELEQWFLRITDYAdrlledldqldrWPERVKVMQRNWIGRSTGAEVEFALEGRPET  252
            V ++ + QW L+IT YA   L +  +   WPE +K MQRNWIG+STGA+V F + +    
Sbjct  184  VVRKPMRQWMLKITAYA-ERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  253  IRVFTTRPDTLLGVTYMVLAPEHPLVPALIEHSSERNRVEAFVEEMRKASEVERTAAEGE  312
            + VFTTRPDTL+G TY VLAPEH+LV A I  S + + V  +  +    S++ RT    E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDA-ITTSDQAEAVADYKRQASLKSDLARTDLAKE  301

Query  313  KRGVFTGTYAIHPLTGDRVPIWVANYVLLDYGTGAVMGVPAHDERDFAFAKKYNLPIRVV  372
            K GV TG+YAI+P+ G  +P+W+A+YVL  YGTGA+M+VPAHDERD  FAK++NL I  V
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  373  IRPEDRELPTPPVEAYVEDGVLVNSGRWDGMHNREAIHAITAHLEEMGKGRFATSYRIRD  432
            +   + E       A+ EDG+ +NS+  DG+++  AI  +   LE  G G    +YR+RD
Sbjct  362  LEGGNVE-----EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  433  WLISRQRYWGAPIPIVYCDHCGIVPVPEDQLPVRLPEDVSFEPGTV--SPLATNEDFVQT  490
            WL+SRQRYWG PIPI+  ++    +VPE +LP+ LP    + P+    SPLA   D ++ 
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  491  TCPKCGGPGRRETDTMDTFMCSSWYYFRYTSPKETARPFDPEAVRKWLPVDDYIGGIEHA  550
            T    G  GRRET+TM     SSWYY+RY  P +T +  D E +++WLPVD Y+GG EHA
Sbjct  477  TRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  551  VLHLLYSRFFTKVLQDAGWVDFSEPFRHLLTQGMVI-------------------KEG--  589
            VLHLLY+RF  KVL D G V   EPF+ L+ QGM++                   ++G  
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSF  595

Query  590  -------------AKMSKSKGNVVSPDDIINRYGADTARLFILFAAPPDRDLEWNDQGVE  636
                         AKMSKS  NVV+PDD++++YGADT R++ +F +P D  + W+++G+E
Sbjct  596  FHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLE  655

Query  637  GSHRFLHRVWRLVNQNREVFHAPAGDRMAPAARDLRRKTHATIKKVTEDFAQRYTFNTGI  696
            GS++FL+RV RL+   +E+ +  +G         L +  + T+K VTE+  Q   FNT+I
Sbjct  656  GSRKFLDRVYRLIT-TKEITEENSG--------ALDKVYNETVKAVTEQVDQM-KFNTAI  705

Query  697  SAIMELVNAIYAYPAEADPFTKAAAIRTVLLLLAPAAPHICEELWSQIGGTG-SVHEQPW  755
            + +M +VNA      E   F+  A  +  + L+AP APH+ EELW  + ++G S+   PW
Sbjct  706  AQLMVFVNAA---NKEDKLFSDYA--KGFVQLIAPFAPHLGEELWQALTASGESISYVPW  760

Query  756  PTYDPAELVTDEVEYAVQVNGKVRDHIVVSASAGEEEVRQTALGAEKIQ  804
            P+YD + LV ++VE  VQ++GKV+  +VV+   + EE+++ AL+ EK+Q
Sbjct  761  PSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQ  809

1215) Thebr_2003 in NC_014964


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  539 bits (2035),  Expect = 3e-154, Method: Compositional matrix adjust.
 Identities = 382/849 (45%), Positives = 542/849 (64%), Gaps = 59/849 (6%)

Query  5    VEIDRKWQKRWEETKLYKFNPKNVDKKLYCLEMFSYPSGAKLHVGHWYNYGPTDSWARMK  64
              I+ KWQ  W +   +K        K+Y L+MF+YPSGA LHVGH   Y +TD  +R K
Sbjct  7    TAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSRFK  66

Query  65   RMQGWEVFHPMGFDAFGLPAENYAIKTGIHPYDSTMENIRTMEKQLKEMGATFDWDYEVI  124
            R QG +V+HPMG DAFGLPAE+YA+ TG +P + T ENI    +Q++ +G ++DWD EV 
Sbjct  67   RAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDREVN  126

Query  125  TCLPEYYKWTQWIFLKLFEAGLAYRKKAPVNWCPSCQTVLANEQVI-DGKCERCGTEVTK  183
            T  P+YYKWTQWIF KL+E GLAY    PVNW     T +ANE+V+ DG  ER G  V +
Sbjct  127  TTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVR  186

Query  184  KDLTQWFFKITAYAeellekldeldWPEKTKIMQRNWIGKSDGAEIEFKVAGKDLTFKVF  243
            K + QW +KITAYAE LLE L+E+DWPE  K MQRNWIGKS GA++ FKV + D  F VF
Sbjct  187  KPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVF  246

Query  244  TTRADTLYGATYVVIAPEHEIVDLITTEEYKQAVEEYKEYARKQSEIERLSTEKEKTGVF  303
            TTR+DTL+GATY V+APEH +VD ITT +  +AV +YK  A  +S++ R    KEKTGV 
Sbjct  247  TTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVW  306

Query  304  TGAYAIHPLTGEKLPIWIADYVLATYGTGCVMAVPAHDKRDYEFATKYNLPIKRVIKGIG  363
            TG+YAI+P+ G  +P+WIADYVLA+YGTG +MAVPAHD RD EFA ++NL I  V+ G G
Sbjct  307  TGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEG-G  365

Query  364  DVEDSLPFDEYGVLVDSGEFAGLKSEEARIKIVEKLKQEGRAEFKVNYRLRDWLVSRQRY  423
            +VE++ +F E G+ ++S+ + GL    A  K+VE L  EG ++ +V YRLRDWL SRQRY
Sbjct  366  NVEEA-AFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRY  424

Query  424  WGAPIPVIH--CERCGIvpvpeedlpvllpYDVEFAPTGESPLKKHEGFMNVTCPKCGGK  481
            WG PIP+IH        VP +E  L + +  D+  + TGESPL +  + ++VT    G K
Sbjct  425  WGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED-GVK  483

Query  482  ALRDPDTLDTFVDSSWYFLRYPDNKNDKEPFNKEWINKMLPVDKYVGGAEHATMHLLYAR  541
            + R+ +T+    +SSWY+LRY D  N     + E +++ LPVD YVGGAEHA +HLLYAR
Sbjct  484  GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYAR  543

Query  542  FVTKALRDLGYLDFDEPFKSLVHQGTILGP------------------------------  571
            F  K L DLG +   EPF+ L +QG ILG                               
Sbjct  544  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEE  603

Query  572  ---DGSRMSKSKGNVISPDEYIKEYGSDVFRLYLMFGFAYSEGGPWNDDGIKAIARFVNR  628
                 ++MSKS  NV++PD+ + +YG+D +R+Y MF  +   + +W+++G+ +  +F++R
Sbjct  604  LEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR  663

Query  629  VERFIDKFIETRNNPGKIKDDMGKDEKELNYVRHYAIKGVTEDAERFQFNTAIARIMELV  688
            V R+I             K+    +   L+ V + ++K+VTE+ ++ +FNTAIA++M +V
Sbjct  664  VYRLI-----------TTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFV  712

Query  689  NALYKYEADVEVKNIKFYEEVVADLIKLLAPFAPHFSEEMWEKLGYEYSVFN-QKWPEWD  747
            NA          K+ K++ +   ++++L+APFAPH++EE+W+ L      ++   WP  D
Sbjct  713  NA--------ANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYD  764

Query  748  EKALQRDVVEIAVQVNGKVRGRLEVPSKATDEEIEKLALSDKNVKAYVDGKEIKKVIVVK  807
            E  L  + VEI VQ++GKV+++L V+   + EE++ +AL++ +V+A + GK+I KVI V 
Sbjct  765  ESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVP  824

Query  808  NRLVNIVVK  816
            N+LVNIV+K
Sbjct  825  NKLVNIVIK  833

1216) leuS in NC_010321


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  539 bits (2035),  Expect = 3e-154, Method: Compositional matrix adjust.
 Identities = 382/849 (45%), Positives = 542/849 (64%), Gaps = 59/849 (6%)

Query  5    VEIDRKWQKRWEETKLYKFNPKNVDKKLYCLEMFSYPSGAKLHVGHWYNYGPTDSWARMK  64
              I+ KWQ  W +   +K        K+Y L+MF+YPSGA LHVGH   Y +TD  +R K
Sbjct  7    TAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSRFK  66

Query  65   RMQGWEVFHPMGFDAFGLPAENYAIKTGIHPYDSTMENIRTMEKQLKEMGATFDWDYEVI  124
            R QG +V+HPMG DAFGLPAE+YA+ TG +P + T ENI    +Q++ +G ++DWD EV 
Sbjct  67   RAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDREVN  126

Query  125  TCLPEYYKWTQWIFLKLFEAGLAYRKKAPVNWCPSCQTVLANEQVI-DGKCERCGTEVTK  183
            T  P+YYKWTQWIF KL+E GLAY    PVNW     T +ANE+V+ DG  ER G  V +
Sbjct  127  TTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVR  186

Query  184  KDLTQWFFKITAYAeellekldeldWPEKTKIMQRNWIGKSDGAEIEFKVAGKDLTFKVF  243
            K + QW +KITAYAE LLE L+E+DWPE  K MQRNWIGKS GA++ FKV + D  F VF
Sbjct  187  KPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVF  246

Query  244  TTRADTLYGATYVVIAPEHEIVDLITTEEYKQAVEEYKEYARKQSEIERLSTEKEKTGVF  303
            TTR+DTL+GATY V+APEH +VD ITT +  +AV +YK  A  +S++ R    KEKTGV 
Sbjct  247  TTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVW  306

Query  304  TGAYAIHPLTGEKLPIWIADYVLATYGTGCVMAVPAHDKRDYEFATKYNLPIKRVIKGIG  363
            TG+YAI+P+ G  +P+WIADYVLA+YGTG +MAVPAHD RD EFA ++NL I  V+ G G
Sbjct  307  TGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEG-G  365

Query  364  DVEDSLPFDEYGVLVDSGEFAGLKSEEARIKIVEKLKQEGRAEFKVNYRLRDWLVSRQRY  423
            +VE++ +F E G+ ++S+ + GL    A  K+VE L  EG ++ +V YRLRDWL SRQRY
Sbjct  366  NVEEA-AFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRY  424

Query  424  WGAPIPVIH--CERCGIvpvpeedlpvllpYDVEFAPTGESPLKKHEGFMNVTCPKCGGK  481
            WG PIP+IH        VP +E  L + +  D+  + TGESPL +  + ++VT    G K
Sbjct  425  WGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED-GVK  483

Query  482  ALRDPDTLDTFVDSSWYFLRYPDNKNDKEPFNKEWINKMLPVDKYVGGAEHATMHLLYAR  541
            + R+ +T+    +SSWY+LRY D  N     + E +++ LPVD YVGGAEHA +HLLYAR
Sbjct  484  GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYAR  543

Query  542  FVTKALRDLGYLDFDEPFKSLVHQGTILGP------------------------------  571
            F  K L DLG +   EPF+ L +QG ILG                               
Sbjct  544  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEE  603

Query  572  ---DGSRMSKSKGNVISPDEYIKEYGSDVFRLYLMFGFAYSEGGPWNDDGIKAIARFVNR  628
                 ++MSKS  NV++PD+ + +YG+D +R+Y MF  +   + +W+++G+ +  +F++R
Sbjct  604  LEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR  663

Query  629  VERFIDKFIETRNNPGKIKDDMGKDEKELNYVRHYAIKGVTEDAERFQFNTAIARIMELV  688
            V R+I             K+    +   L+ V + ++K+VTE+ ++ +FNTAIA++M +V
Sbjct  664  VYRLI-----------TTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFV  712

Query  689  NALYKYEADVEVKNIKFYEEVVADLIKLLAPFAPHFSEEMWEKLGYEYSVFN-QKWPEWD  747
            NA          K+ K++ +   ++++L+APFAPH++EE+W+ L      ++   WP  D
Sbjct  713  NA--------ANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYD  764

Query  748  EKALQRDVVEIAVQVNGKVRGRLEVPSKATDEEIEKLALSDKNVKAYVDGKEIKKVIVVK  807
            E  L  + VEI VQ++GKV+++L V+   + EE++ +AL++ +V+A + GK+I KVI V 
Sbjct  765  ESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVP  824

Query  808  NRLVNIVVK  816
            N+LVNIV+K
Sbjct  825  NKLVNIVIK  833

1217) leuS in NC_011750


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  539 bits (2034),  Expect = 3e-154, Method: Compositional matrix adjust.
 Identities = 358/865 (42%), Positives = 556/865 (65%), Gaps = 46/865 (5%)

Query  5    YRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIA  63
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADELLNNLDKLDHWPDTVKTMQRNWIGRSEGVEITFNVNDYDNT  242
            V RK + QW +KITAYA+ LL++L+ +D WP+++K MQRNWIG+S G ++TF+V+D D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGCTYLAVAAGHPLAQ--KAAENNPELAAFIDECR-NTKVAEAEMATME  299
            +TV+TTRPDT+ G TY  +A+ H+L +   ++++   +A +  +   ++ +A +++A  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGVDTGFKAVHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPV  359
            K GV TG  A++P+ G E+PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L+I PV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  360  ILAADGSEPDLSQQALTEKGVLFNSGEFNGLDHEAAFNAIADKLTAMGVGERKVNYRLRD  419
            +        ++ + A+TE G+ +NS+ ++GLD  +A+  + + L A GVG+ +V YRLRD
Sbjct  362  L-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMVTLEDGTVMPTPDDQLPVILP--EDVVMDGIT-SPIKADPEWAKT  476
            W  SRQRYWG PIP++  EDGT  + P+ +LP++LP   D+   G   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  T-VNGMPALRETDTFDTFMESSWYYARYTCPEYKEGMLDSKAANYWLPVDIYIGGIEHAI  535
            T  +G+ + RET+T      SSWYY RY  P+  E + D    + WLPVDIY+GG EHA+
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVER  595
            +HLLY RF HK++ D G+V + EP ++L+ QGM+L+ ++      + R  + + D +  R
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEKR  591

Query  596  DEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMT  655
            D  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D +
Sbjct  592  D--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  656  LEWQESGVEGANRFLKRVWKLVYEHTAKGDVAALNVDALTEDQKALRRDVHKTIAKVTDD  715
            + W E G+EG+ +FL RV +L+   T+K        +   E+  AL +  + T+  VT++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLI---TTK--------EITEENSGALDKVYNETVKAVTEQ  695

Query  716  IGRRQTFNTAIAAIMELMNKLAKAPTDGEQDRALMQEALLAVIRMLNPFTPHICFTLWQE  775
            +++ + FNTAIA +M ++N        ++++  L  +   + ++++ PF+PH+   LWQ 
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  776  LKGEGD-IDNAPWPVADEKAMVEDSTLVVVQVNGKVRAKITVPVDATEEQVRERAGQEHL  834
            L + G+ I   PWP  DE  +VE+   +VVQ++GKV+AK+ V+ D + E+++E A  ++ 
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  835  VAKYLDGVTVRKVIYVPGKLLNLVV  859
            V   + G  + KVI VP KL+N+V+
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVI  832

1218) leuS in NC_017646


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  539 bits (2034),  Expect = 3e-154, Method: Compositional matrix adjust.
 Identities = 358/865 (42%), Positives = 556/865 (65%), Gaps = 46/865 (5%)

Query  5    YRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIA  63
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADELLNNLDKLDHWPDTVKTMQRNWIGRSEGVEITFNVNDYDNT  242
            V RK + QW +KITAYA+ LL++L+ +D WP+++K MQRNWIG+S G ++TF+V+D D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGCTYLAVAAGHPLAQ--KAAENNPELAAFIDECR-NTKVAEAEMATME  299
            +TV+TTRPDT+ G TY  +A+ H+L +   ++++   +A +  +   ++ +A +++A  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGVDTGFKAVHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPV  359
            K GV TG  A++P+ G E+PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L+I PV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  360  ILAADGSEPDLSQQALTEKGVLFNSGEFNGLDHEAAFNAIADKLTAMGVGERKVNYRLRD  419
            +        ++ + A+TE G+ +NS+ ++GLD  +A+  + + L A GVG+ +V YRLRD
Sbjct  362  L-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMVTLEDGTVMPTPDDQLPVILP--EDVVMDGIT-SPIKADPEWAKT  476
            W  SRQRYWG PIP++  EDGT  + P+ +LP++LP   D+   G   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  T-VNGMPALRETDTFDTFMESSWYYARYTCPEYKEGMLDSKAANYWLPVDIYIGGIEHAI  535
            T  +G+ + RET+T      SSWYY RY  P+  E + D    + WLPVDIY+GG EHA+
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVER  595
            +HLLY RF HK++ D G+V + EP ++L+ QGM+L+ ++      + R  + + D +  R
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEKR  591

Query  596  DEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMT  655
            D  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D +
Sbjct  592  D--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  656  LEWQESGVEGANRFLKRVWKLVYEHTAKGDVAALNVDALTEDQKALRRDVHKTIAKVTDD  715
            + W E G+EG+ +FL RV +L+   T+K        +   E+  AL +  + T+  VT++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLI---TTK--------EITEENSGALDKVYNETVKAVTEQ  695

Query  716  IGRRQTFNTAIAAIMELMNKLAKAPTDGEQDRALMQEALLAVIRMLNPFTPHICFTLWQE  775
            +++ + FNTAIA +M ++N        ++++  L  +   + ++++ PF+PH+   LWQ 
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  776  LKGEGD-IDNAPWPVADEKAMVEDSTLVVVQVNGKVRAKITVPVDATEEQVRERAGQEHL  834
            L + G+ I   PWP  DE  +VE+   +VVQ++GKV+AK+ V+ D + E+++E A  ++ 
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  835  VAKYLDGVTVRKVIYVPGKLLNLVV  859
            V   + G  + KVI VP KL+N+V+
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVI  832

1219) leuS in NC_010498


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  539 bits (2035),  Expect = 3e-154, Method: Compositional matrix adjust.
 Identities = 358/865 (42%), Positives = 556/865 (65%), Gaps = 46/865 (5%)

Query  5    YRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIA  63
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKTMQRNWIGRSEGVEITFNVNDYDNT  242
            V RK + QW +KITAYA+ LL+DL+ +D WP+++K MQRNWIG+S G ++TF+V+D D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGCSYLAVAAGHPLAQ--KAAENNPELAAFIDECR-NTKVAEAEMATME  299
            +TV+TTRPDT+ G +Y  +A+ H+L +   ++++   +A +  +   ++ +A +++A  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGVDTGFKAVHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPV  359
            K GV TG  A++P+ G E+PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L+I PV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  360  ILAADGSEPDLSQQALTEKGVLFNSGEFNGLDHEAAFNAIADKLTAMGVGERKVNYRLRD  419
            +        ++ + A+TE G+ +NS+ ++GLD  +A+  + + L A GVG+ +V YRLRD
Sbjct  362  L-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMVTLEDGTVMPTPDDQLPVILP--EDVVMDGIT-SPIKADPEWAKT  476
            W  SRQRYWG PIP++  EDGT  + P+ +LP++LP   D+   G   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  T-VNGMPALRETDTFDTFMESSWYYARYTCPEYKEGMLDSKAANYWLPVDIYIGGIEHAI  535
            T  +G+ + RET+T      SSWYY RY  P+  E + D    + WLPVDIY+GG EHA+
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVER  595
            +HLLY RF HK++ D G+V + EP ++L+ QGM+L+ ++      + R  + + D +  R
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEKR  591

Query  596  DEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMT  655
            D  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D +
Sbjct  592  D--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  656  LEWQESGVEGANRFLKRVWKLVYEHTAKGDVAALNVDALTEDQKALRRDVHKTIAKVTDD  715
            + W E G+EG+ +FL RV +L+   T+K        +   E+  AL +  + T+  VT++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLI---TTK--------EITEENSGALDKVYNETVKAVTEQ  695

Query  716  IGRRQTFNTAIAAIMELMNKLAKAPTDSEQDRALMQEALLAVIRMLNPFTPHICFTLWQE  775
            +++ + FNTAIA +M ++N        ++++  L  +   + ++++ PF+PH+   LWQ 
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  776  LKGEGD-IDNAPWPVADEKAMVEDSTLVVVQVNGKVRAKITVPVDATEEQVRERAGQEHL  834
            L + G+ I   PWP  DE  +VE+   +VVQ++GKV+AK+ V+ D + E+++E A  ++ 
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  835  VAKYLDGVTVRKVIYVPGKLLNLVV  859
            V   + G  + KVI VP KL+N+V+
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVI  832

1220) GNIT_2076 in NC_016041


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  539 bits (2035),  Expect = 3e-154, Method: Compositional matrix adjust.
 Identities = 365/880 (42%), Positives = 554/880 (63%), Gaps = 61/880 (6%)

Query  11   YDPQAVEKSAQTHWDETQIFAAKQDDNREKFYCLSMFPYPSGR-LHMGHVRNYTIGDVVS  69
            YD  A+E   Q+ W + + F +  D ++ KFY L MFPYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  70   RFHRMQGKNVLQPMGWDAFGLPAENAAINNKSAPAKWTYQNIDYMKTQLNSLGFGYDWSR  129
            RF R QG NVL+PMGWDAFGLPAE+ A++  + PA  T +NI   K Q+N+LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  130  ELATCKQDYYRWEQWFFTRLFDKGLVYKKNATVNWDPVDQTVLANEQVI-DGRGWRSGAL  188
            E+ T   +YY+W QW+FT+L++KGL Y  +  VNW     T +ANE+V+ DG + R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  189  VEQKEIPQWFIKITNYAEQLLTDLDKLSEWPQQVVTAQRNWIGRSEGVDVTFDLSAETAG  248
            V +K + QW +KIT YAE+LL DL+ + +WP+ +   QRNWIG+S G +VTF +     +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  249  ISQIEVYTTRPDTLYGVSYLAVAAQHPLALEMAKSNPDMTAFIDECKNTKTTEADMA---  305
            ++   V+TTRPDTL+G +Y  +A++H+L   ++ S+   +  + + K   +  +D+A   
Sbjct  243  FT---VFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEA--VADYKRQASLKSDLARTD  297

Query  306  -TMEKRGMPTGLSAIHPLTGETIPIWIANFVLMSYGSGAVMSVPAHDQRDWEFATKYQLP  364
             + EK G+ TG  AI+P+ G  +P+WIA++VL SYG+GA+M+VPAHD+RDWEFA +++L 
Sbjct  298  LAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLD  357

Query  365  ILQVVEFTPNDADTADISKAAYTEKNTLMNSAEYSGLSFKDGFDAIAEKLATLGKGKKSI  424
            I+ V+E        +++  AA+TE    +NS    GL    ++  + E L + G G+ ++
Sbjct  358  IIPVLE-------GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENV  410

Query  425  NYRLRDWGVSRQRYWGAPIPVVTNENGESFAVNAEDLPVVLP--EDVVMDGVT-SPIKAD  481
             YRLRDW  SRQRYWG PIP++  E+G S AV   +LP+VLP   D+   G   SP+   
Sbjct  411  TYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANV  470

Query  482  PDWAKATH-NGQPVTRETDTFDTFMESSWYYARYASAPSDAMLDPKE-ANYWLPVDQYIG  539
             DW   T+ +G    RET+T      SSWYY RY  + +   L   E  + WLPVD Y+G
Sbjct  471  TDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVG  530

Query  540  GIEHAILHLLYARFFHKLLRDEDLVTSDEPFKKLLCQGMVLADAFFTKDEKGKEIWHAPT  599
            G EHA+LHLLYARF HK+L D ++V + EPF+KL+ QGM+L+ ++  +D +G       +
Sbjct  531  GAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY--RDSRG-------A  581

Query  600  DVIVEKDDKGRIAKATLADGTEVEHAGMIKMGKSKNNGIDPQAVIDIYGADTVRLFTMFA  659
             V  +K +K   +   +  G E+E+A   KM+KS +N ++P+ V++ YGADT+R++ MF 
Sbjct  582  LVATDKVEKRDGSFFHVETGEELEQAP-AKMSKSLKNVVNPDDVVEQYGADTLRVYEMFM  640

Query  660  APPEQTLEWIDSGVEGSHRFLKRFWRLANEHCELCESKGGVPKLNKASLNKTQKALRREI  719
            +P + ++ W + G+EGS++FL R  RL     E+ E ++G              AL +  
Sbjct  641  GPLDASIAWSEEGLEGSRKFLDRVYRLITTK-EITEENSG--------------ALDKVY  685

Query  720  HQTIEKVTDDLGRRQTFNTAVAKVMELLNSLQKAEMLDDQDIALQREGLMAMVQLLNPIT  779
            ++T+  VT+++++ + FNTA+A++M ++N+ +K +        L  +   + VQL+ P++
Sbjct  686  NETVKAVTEQVDQMK-FNTAIAQLMVFVNAANKEDK-------LFSDYAKGFVQLIAPFA  737

Query  780  PHICEALWTLLGGKSADGKGELQTSPWPQVDASALVEDEKLIVVQVNGKVRAKMTVAADI  839
            PH+ E LW  L + +      +   PWP  D S LVE++  IVVQ++GKV+AK+ VA D+
Sbjct  738  PHLGEELWQALTASGES----ISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDL  793

Query  840  SSeqaqeealaqeNVQPFIDGKTVRKVIYIAGKLVNIVAN  879
            S E+ QE ALA+E+VQ+ I GK + KVI ++ KLVNIV +
Sbjct  794  SREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

1221) leuS in NC_016822


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  539 bits (2035),  Expect = 3e-154, Method: Compositional matrix adjust.
 Identities = 361/865 (42%), Positives = 556/865 (65%), Gaps = 46/865 (5%)

Query  5    YRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIA  63
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKTMQRNWIGRSEGVEITFNVNDYDNM  242
            V RK + QW +KITAYA+ LL+DL+ +D WP+++K MQRNWIG+S G ++TF+V+D D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGCTYLAVAAGHPLAQ--KAAENNPELAAFIDECR-NTKVAEAEMATME  299
            +TV+TTRPDT+ G TY  +A+ H+L +   ++++   +A +  +   ++ +A +++A  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGVDTGFKAVHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPV  359
            K GV TG  A++P+ G E+PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L+I PV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  360  ILAADGSEPDLSQQALTEKGVLFNSGEFNGLDHEAAFNAIADKLTAMGVGERKVNYRLRD  419
            +        ++ + A+TE G+ +NS+ ++GLD  +A+  + + L A GVG+ +V YRLRD
Sbjct  362  L-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMVTLEDGTVMPTPDDQLPVILP--EDVVMDGIT-SPIKADPEWAKT  476
            W  SRQRYWG PIP++  EDGT  + P+ +LP++LP   D+   G   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  T-VNGMPALRETDTFDTFMESSWYYARYTCPEYKEGMLDSEAANYWLPVDIYIGGIEHAI  535
            T  +G+ + RET+T      SSWYY RY  P+  E + D E  + WLPVDIY+GG EHA+
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVER  595
            +HLLY RF HK++ D G+V + EP ++L+ QGM+L+ ++      + R  + + D +  R
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEKR  591

Query  596  DEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMT  655
            D  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D +
Sbjct  592  D--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  656  LEWQESGVEGANRFLKRVWKLVYEHTAKGDVAALNVDALTEDQKALRRDVHKTIAKVTDD  715
            + W E G+EG+ +FL RV +L+   T+K        +   E+  AL +  + T+  VT++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLI---TTK--------EITEENSGALDKVYNETVKAVTEQ  695

Query  716  IGRRQTFNTAIAAIMELMNKLAKAPTDGEQDRALMQEALLAVVRMLNPFTPHICFTLWQE  775
            +++ + FNTAIA +M ++N        ++++  L  +   + V+++ PF+PH+   LWQ 
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  776  LKGEGD-IDNAPWPVADEKAMVEDSTLVVVQVNGKVRAKITVLVDATEEQVRERAGQEHL  834
            L + G+ I   PWP  DE  +VE+   +VVQ++GKV+AK+ V  D + E+++E A  ++ 
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  835  VAKYLDGVTVRKVIYVPGKLLNLVV  859
            V   + G  + KVI VP KL+N+V+
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVI  832

1222) leuS in NC_007384


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  539 bits (2035),  Expect = 3e-154, Method: Compositional matrix adjust.
 Identities = 361/865 (42%), Positives = 556/865 (65%), Gaps = 46/865 (5%)

Query  5    YRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIA  63
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKTMQRNWIGRSEGVEITFNVNDYDNM  242
            V RK + QW +KITAYA+ LL+DL+ +D WP+++K MQRNWIG+S G ++TF+V+D D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGCTYLAVAAGHPLAQ--KAAENNPELAAFIDECR-NTKVAEAEMATME  299
            +TV+TTRPDT+ G TY  +A+ H+L +   ++++   +A +  +   ++ +A +++A  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGVDTGFKAVHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPV  359
            K GV TG  A++P+ G E+PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L+I PV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  360  ILAADGSEPDLSQQALTEKGVLFNSGEFNGLDHEAAFNAIADKLTAMGVGERKVNYRLRD  419
            +        ++ + A+TE G+ +NS+ ++GLD  +A+  + + L A GVG+ +V YRLRD
Sbjct  362  L-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMVTLEDGTVMPTPDDQLPVILP--EDVVMDGIT-SPIKADPEWAKT  476
            W  SRQRYWG PIP++  EDGT  + P+ +LP++LP   D+   G   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  T-VNGMPALRETDTFDTFMESSWYYARYTCPEYKEGMLDSEAANYWLPVDIYIGGIEHAI  535
            T  +G+ + RET+T      SSWYY RY  P+  E + D E  + WLPVDIY+GG EHA+
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVER  595
            +HLLY RF HK++ D G+V + EP ++L+ QGM+L+ ++      + R  + + D +  R
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEKR  591

Query  596  DEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMT  655
            D  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D +
Sbjct  592  D--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  656  LEWQESGVEGANRFLKRVWKLVYEHTAKGDVAALNVDALTEDQKALRRDVHKTIAKVTDD  715
            + W E G+EG+ +FL RV +L+   T+K        +   E+  AL +  + T+  VT++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLI---TTK--------EITEENSGALDKVYNETVKAVTEQ  695

Query  716  IGRRQTFNTAIAAIMELMNKLAKAPTDGEQDRALMQEALLAVVRMLNPFTPHICFTLWQE  775
            +++ + FNTAIA +M ++N        ++++  L  +   + V+++ PF+PH+   LWQ 
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  776  LKGEGD-IDNAPWPVADEKAMVEDSTLVVVQVNGKVRAKITVLVDATEEQVRERAGQEHL  834
            L + G+ I   PWP  DE  +VE+   +VVQ++GKV+AK+ V  D + E+++E A  ++ 
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  835  VAKYLDGVTVRKVIYVPGKLLNLVV  859
            V   + G  + KVI VP KL+N+V+
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVI  832

1223) Entcl_3155 in NC_014618


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  539 bits (2034),  Expect = 3e-154, Method: Compositional matrix adjust.
 Identities = 355/866 (41%), Positives = 552/866 (64%), Gaps = 48/866 (5%)

Query  5    YRPEEIESNVQQHWDEKRTFEVTEDNSKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIA  63
            Y    IE++ Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKTMQRNWIGRSEGVEITFDVNGYDNT  242
            V RK + QW +KITAYA+ LL+DL+ +D WP+++K MQRNWIG+S G ++TF V++ D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGATYLAVAAGHPLAQKAAAGNPTLAAFIDECRNTKVAEADMA----TM  298
            +TV+TTRPDT+ GATY  +A+ H+L +  ++++ + A  + + +      +D+A    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEA--VADYKRQASLKSDLARTDLAK  300

Query  299  EKKGVDTGFKAIHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFATKYGLTIKP  358
            EK GV TG  AI+P+ G E+PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L I P
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VILAADGSAPDLSAQALTEKGVLFNSGEFDGLGFEDAFNAIADKLAAKGVGERKVNFRLR  418
            V+      + ++   A+TE G+ +NS+ +DGL+   A+  + + L A GVG+ +V +RLR
Sbjct  361  VL-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  419  DWGVSRQRYWGAPIPMVTLEDGTVMPTPEDQLPVILP--EDVVMDGIT-SPIKADPEWAK  475
            DW  SRQRYWG PIP++  EDGT  + PE +LP++LP   D+   G   SP+    +W  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  476  TT-VNGQPALRETDTFDTFMESSWYYARYTCPQYQEGMLDADAANYWLPVDIYIGGIEHA  534
             T  +G  + RET+T      SSWYY RY  P+  E + D +  + WLPVDIY+GG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  535  IMHLLYFRFFHKLMRDAGMVSSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPKDAIVE  594
            ++HLLY RF HK++ D G+V++ EP ++L+ QGM+L+ ++      + R  + + D +  
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEK  590

Query  595  RDEKGRIVKAKDGEGHELVYTGMSKMSKSKNNGIDPQEMVERYGADTVRLFMMFASPADM  654
            RD  G +     GE  E    + +KMSKS +N ++P+++VE+YGADT+R++ MF +P D 
Sbjct  591  RD--GSFFHVETGEELE---QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  655  TLEWQESGVEGANRFLKRLWKLVYEHNAQGPVAALNVDALSDDQQALRRDVHKTIAKVTD  714
            ++ W E G+EG+ +FL R+ +L+              +   ++  AL +  + T+  VT+
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLI-----------TTKEITEENSGALDKVYNETVKAVTE  694

Query  715  DIGRRQTFNTAIAAIMELMNKLAKAPTDGEQDRALLQEALLAVVRMLNPFTPHICFTLWQ  774
            ++++ + FNTAIA +M ++N        ++++  L+ +   + V+++ PF+PH+   LWQ
Sbjct  695  QVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  775  TLGGAGD-IDNAPWPVADDKAMVENSTLVVVQVNGKVRGKITVPVDATEEQVRERAGQEH  833
            +L ++G+ I   PWP  D+  +VEN   +VVQ++GKV++K+ V+ D + E+++E A  ++
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  834  LVAKYLDGVTVRKVIYVPGKLLNLVV  859
             V   + G  + KVI VP KL+N+V+
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVI  832

1224) leuS in NC_009976


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  539 bits (2034),  Expect = 3e-154, Method: Compositional matrix adjust.
 Identities = 349/868 (41%), Positives = 563/868 (65%), Gaps = 54/868 (6%)

Query  18   YQPQLIEEKWQNEWKISGLYKTREPKEDQKTFYALSMFPYPSG-NLHMGHVRNYVITDVI  76
            Y+   IE KWQ  W  +  +KT      +  FYAL MFPYPSG  LH+GH   Y  TD++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKT-GTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDIL  62

Query  77   ARVHRMKGFSVLHPMGWDAFGLPAENAAIERNIQPDIWTEKNISHMRSQLDRLGLSIDWD  136
            +R  R +G +VLHPMGWDAFGLPAE+ A++   +P   T  NI++ + Q++ LG+S DWD
Sbjct  63   SRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWD  122

Query  137  REQTTSKSEYYKWTQSIFLKLYEAGLAYQKSATVNWDPVDKTVLANEQVDADGKSWRSGA  196
            RE  T+ ++YYKWTQ IF KLYE GLAY+    VNW     T +ANE+V +DG S R+G 
Sbjct  123  REVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGY  182

Query  197  LVEKKQLKQWFLKITDYAEILLKDIDTLTEWPERVKTMQSNWIGKSVGVKINFQLLTKEK  256
             V +K ++QW LKIT YAE LL D++ + +WPE +K MQ NWIGKS G ++ F++   +K
Sbjct  183  PVVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDK  241

Query  257  ENLSVFTTRPDTLFGSTYLVLSPEDKLVDKLVDPKLINDLSNFRDYVSKLSDKERTAEGK  316
            + ++VFTTRPDTLFG+TY VL+PE+ LVD +  +   + +++++   S  SD  RT  +K
Sbjct  242  D-FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  317  PKNGMAIGAYAINPINQEKLPIWIADYVLSGYGTGAVMGVPAHDQRDLDFAQKYSLPIKY  376
             K G+  G+YAINP+N   +P+WIADYVL++YGTGA+M+VPAHD+RD +FA++++L I  
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  377  VIKPSGIIEKKKEVKAYSEVGVMINSGPFNG-QKSDEVKSLI---TEKGIKENWAEKKTT  432
            V+  + +     E  A++E G+ INS+ ++G +K+  +  ++      G+    ++ + T
Sbjct  361  VLEGGNV-----EEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGV----GNENVT  411

Query  433  YKLRDWLISRQRYWGCPIPIVHCAKCGIVPIEKENLPVFLPT--NIQLSGKGNSPLKD-N  489
            Y+LRDWL+SRQRYWG PIPI+H       ++   +LP+ LP   +I+ SG G+SPL +  
Sbjct  412  YRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVT  471

Query  490  EWTKTQCPICKGI-ARRESDTMDTFICSSWYYLRFidpnnkkniidknLADRWMPVDQYV  548
            +W   +     G+ +RRE++TM     SSWYYLR+IDP+N  ++ D +L  +W+PVD YV
Sbjct  472  DW--LEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYV  529

Query  549  GGIEHAILHLLYARFITKVLRDKDMISIDEPFKKLLTQGMVQGITFKNPKTGKYIPPNKI  608
            GG EHA+LHLLYARF  KVL D ++++  EPF+KL+ QGM+ G ++++++ G  ++ +K+
Sbjct  530  GGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSR-GALVATDKV  588

Query  609  NNIKTP-LDPSTGESLELIYEKMSKSKHNGIDPSTVIDKYGADTARMFILFKAPPEKDLE  667
            ++   + ++  TGE LE    KMSKS  N ++P  V+++YGADT R++ +F +P +  + 
Sbjct  589  EKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIA  648

Query  668  WDDADVEGQYRFLQRLWRLINESKTYnklsldsnennnlnnlnQDEISLRRSVHLAIKEI  727
            W + ++EG  +FL+R+ RLI                      +++  +L +  + ++K +
Sbjct  649  WSEEGLEGSRKFLDRVYRLITTKEI----------------TEENSGALDKVYNETVKAV  692

Query  728  SNDLNEGNQFNTAISELM---KLSNNMNELLGKCRISVVNESLSILIRILSPFAPHLAEE  784
            ++++++  +FNTAI++LM   + +N+ + L++    +        ++++++PFAPHL+EE
Sbjct  693  TEQVDQ-MKFNTAIAQLMVFVNAANKEDKLFSDYAKG--------FVQLIAPFAPHLGEE  743

Query  785  AWSTLKGKG-SVHEQKWPEFDPNALKQDNYQLVIQMNGKVRGSIKIASETNKQEIEKIAL  843
             W +L + G S+    WP +D + L +++ ++V+Q++GKV++ + +A + +++E++ +AL
Sbjct  744  LWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVAL  803

Query  844  NSDIAKKWLIDGSYKKVIVVLGKLVNIV  871
             ++  +  + +    KVI V  KLVNIV
Sbjct  804  ANEKVQAEIAGKDIIKVIAVPNKLVNIV  831

1225) leuS in NC_009831


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  539 bits (2035),  Expect = 3e-154, Method: Compositional matrix adjust.
 Identities = 354/870 (41%), Positives = 554/870 (64%), Gaps = 51/870 (5%)

Query  5    YKPSEIEAKVQQHWQDKKTFEVTEDENKEKFYCLSMFPYPSGR-LHMGHVRNYTIGDVVA  63
            Y  + IE+K Q  W D+ TF    D +K KFY L MFPYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRLQGKNVLQPIGWDSFGLPAENAAIKNNTAPAPWTYENIDYMKNQLKMLGFGYDWSR  123
            R++R QG NVL+P+GWD+FGLPAE+ A+     PA  T ENI   K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EIATCTPEYYRWEQWFFTKLFEKGLVYKKTASVNWCPNDETVLANEQVI-DGCCWRCDTT  182
            E+ T  P+YY+W QW+FTKL+EKGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VEQKEIPQWFIKITEYADELLKDIDQLDEWPEQVKTMQRNWIGRSEGIEMTFGVVDSEET  242
            V +K + QW +KIT YA+ LL D++++D WPE +K MQRNWIG+S G ++TF V D++  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  FDIYTTRPDTVMGVTYVAIAAGHPLAE--KAAANNSELSDFIEECKNADtteaamaamek  300
            F ++TTRPDT+ G TY  +A+ H+L +   ++ +   ++D+  +         +  A EK
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEK  302

Query  301  kGVATGLYATHPLTGKQVPIWAANFVLMNYGTGAVMSVPAHDQRDYEFATKYGLAIEGVI  360
             GV TG YA +P+ GK++P+W A++VL +YGTGA+M+VPAHD+RD EFA ++ L I  V+
Sbjct  303  TGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL  362

Query  361  KPSDSDLDISEEAYTEKGVLFNSGDSFPELDGLDFQDAFDAIDAKLSSEGKGKRQVNFRL  420
              +    ++ E A+TE G+ +NS+  F  LDGLD   A+  +   L +EG G+ +V +RL
Sbjct  363  EGG----NVEEAAFTEDGLHINSD--F--LDGLDKASAIAKMVEWLEAEGVGNENVTYRL  414

Query  421  RDWGVSRQRYWGAPIPMVTLADGTVVPTPEDQLPVILP--EDVVMDGI-QSPIKADKEWA  477
            RDW  SRQRYWG PIP++   DGT  + PE +LP++LP   D+   G  +SP+    +W 
Sbjct  415  RDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWL  474

Query  478  K-TQINGQEAFRETDTFDTFMESSWYYARYCSPHADEML-DPAKANYWLPVDQYIGGIEH  535
              T+ +G  + RET+T      SSWYY RY  PH  E L D    + WLPVD Y+GG EH
Sbjct  475  EVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEH  534

Query  536  ACMHLLYFRFFHKLLRDIGLVNSDEPAKRLLTQGMVLADAFYYNNEKGARVWVAPSDVTV  595
            A +HLLY RF HK+L D+G+V + EP ++L+ QGM+L+ +  Y + +GA        V+ 
Sbjct  535  AVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS--YRDSRGAL-------VAT  585

Query  596  QETDEKGRIQKAVDSEGHELVYTGMSKMSKSKNNGIDPQVMVDKYGADTVRLFMMFAAPP  655
            +  + ++     V++ G+EL   + +KMSKS +N ++P+ +V++YGADT+R++ MF +P 
Sbjct  586  DKVEKRDGSFFHVET-GEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPL  643

Query  656  ELTLEWQESSVEGAHRFIKRLWK-VAHDHVAKGATAPLDVKTLDTKQKELRRELHKTIVK  714
            + ++ W E ++EG+++F+ R+ + ++  +++   +++LD            +  + T+  
Sbjct  644  DASIAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALD------------KVYNETVKA  691

Query  715  VGDDIERRQMFNTAIASVMELMNRLQKAPTETQQDRALMQEALSAVVRLLYPIIPHTSFS  774
            V +++++ + FNTAIA +M ++N        ++++  L  +   + V+L+ P+ PH +  
Sbjct  692  VTEQVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEE  743

Query  775  LWNDL-GNEENIEDVRWPEADQSALVEDSKLIIVQVNGKLRAKITVPADATKEVVEEQGF  833
            LW+ L ++ E+I  V WP  D+S LVE+   I+VQ++GK++AK+ V+ D ++E ++E ++
Sbjct  744  LWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVAL  803

Query  834  AEEGVIKHTEGKTVRKVIYVPGKLLNIVAN  863
            A+E V  +  GK + KVI VP KL+NIV +
Sbjct  804  ANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

1226) leuS in NC_007759


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  539 bits (2035),  Expect = 3e-154, Method: Compositional matrix adjust.
 Identities = 351/864 (41%), Positives = 553/864 (65%), Gaps = 41/864 (4%)

Query  5    YVPQEIEEKWQRYWEEKNTFKVTEDPSKKKYYLLEMFPYPSGK-IHIGHVRNYTIGDVVA  63
            Y    IE KWQ +W +++TFK   D+SK K+Y L+MFPYPSG  +H+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYKRMEGYNVLHPMGWDSFGMPAENAAIERGIHPSLWTNENITHMRKQLKRMGFSYDWDR  123
            R+KR +G NVLHPMGWD+FG+PAE+ A++ G +P+  T ENI++ ++Q++ +GFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVSTCEPVYYRWEQLFFLWMYEKGLAYKKTSSVNWCPRCQTVLANEQV-EAGLCWRCGSE  182
            EV+T +P YY+W Q +F  +YEKGLAY    +VNW     T +ANE+V   G   R G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VVEKILDQWFFRITAYIDELLAGCDRLTGWPERVLTMQRNWIGKSYGCEVSFPMADGNGD  242
            VV K + QW ++ITAY + LL + + + +WPE +  MQRNWIGKS G +V+F + D + D
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  IKVFTTRQDTLFGATFMLIAAEHPLVMELIKGKPVEKDARTFAEEVKKQDKLMRTSDYYE  302
            + VFTTR DTLFGAT+ ++A+EH+LV  +  +   E     +  +   +  L RT    E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAE-AVADYKRQASLKSDLARTDLAKE  301

Query  303  KQGLFLDCYCLNPLTGWEMPIFATNFVLADYGTGCVMAVPTHDQRDFEFAEKFGLRKVVV  362
            K G+  + Y +NP+ G EMP+  +++VLA YGTG +MAVP+HD+RD EFA +F L  + V
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  363  ISPPDKTLDPETMTEAYVEEGILVNSGPFNGMENlkaldaiadhlialGRGKRTIQYRLR  422
            +       + +    A+ E+G+ +NS+ ++G+++  A+  + + L A G G+  + YRLR
Sbjct  362  LE------GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  423  DWGISRQRYWGAPIPMIM--CPKCGTvpvpeaelpvvlpRDVDFSGEGGSPLAKHPEFLN  480
            DW +SRQRYWG PIP+I        +VP +E  L + + +D+  SG G SPLA+  + L+
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  481  TTCPSCGGPAKRESDTMDTFVESSWYFERYCCPHFAEKPGLNRQQVDYWMPVDQYIGGIE  540
             T    G  ++RE++TM     SSWY+ RY  PH +EK + + + +  W+PVD Y+GG E
Sbjct  476  VTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLA-DEELLKQWLPVDIYVGGAE  533

Query  541  HAILHLLYARFYTRMLRDFGLVGVDEPFTNLLTQGMVCKETTRCPDHGYLYPEEV--REG  598
            HA+LHLLYARF  ++L D+G+V   EPF +L+ QGM+   + R +  + +  + V  R+G
Sbjct  534  HAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDG  593

Query  599  RCIHC-LAEVIVGKTEKMSKSLKNVVDPDYLVRQYGADTARMFCLFAAPPEKDLEWSDQG  657
              +H   +E +     KMSKSLKNVV+PD +V QYGADT R++ +F +P +  + WS++G
Sbjct  594  SFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEG  653

Query  658  VEGSFRFIGRTWRIVVDYLDDLQGIAPFAGDGELEGELKSLRRKTHQTIRKVRDDMGERF  717
            +EGS +F++R  R++             +     E +  +L +  ++T++ V +++ ++ 
Sbjct  654  LEGSRKFLDRVYRLI-------------TTKEITEENSGALDKVYNETVKAVTEQV-DQM  699

Query  718  HFNTAISAIMELVNTLYGLPRPPREDRTALAVIRETIEAIILLLAPIVPHLTEELWQMLG  777
             FNTAI+ +M +VN+      + +ED+    ++ +   +++ L+AP+ PHL EELWQ L 
Sbjct  700  KFNTAIAQLMVFVNA------ANKEDK----LFSDYAKGFVQLIAPFAPHLGEELWQALT  749

Query  778  HQGTCLADTPLPVYDPTVAAEDEMTIVIQVNGKVRSRVIVAADEAEDKIKALAMGDEKVS  837
              G  ++  P P YD +   E+++ IV+Q++GKV+++++VA D + + ++ +A+++EKV 
Sbjct  750  ASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQ  809

Query  838  RFLEGKSVIKQVYVPKKLVNIVVK  861
              + GK +IK + VP+KLVNIV+K
Sbjct  810  AEIAGKDIIKVIAVPNKLVNIVIK  833

1227) leuS in NC_013971


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  539 bits (2033),  Expect = 4e-154, Method: Compositional matrix adjust.
 Identities = 356/866 (42%), Positives = 545/866 (63%), Gaps = 48/866 (5%)

Query  5    YRPEEIESHVQQHWDDKQTFKVIEEEGKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIS  63
            Y    IE+  Q  W D++TFK   + +K K+Y L M+PYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYANIDYMKNQLKLLGFGYDWHR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T  NI   K Q++ LGF+YDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCQPEYYRWEQWFFTKLYEKGLVYKKTSAVNWCPHDMTVLANEQVI-DGCCWRCDSK  182
            E+ T +P+YY+W QW+FTKLYEKGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFVKITDYADELLNDLDKLESWPEQVKTMQRNWIGRSEGVEIEFSVIDSEEK  242
            V RK + QW +KIT YA+ LL+DL+ ++ WPE +K MQRNWIG+S G ++ F V D++  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LGVYTTRPDTFMGVTYLAVAAGHPLASQAAMTNPALADFIAECRNTKVAEADMA----TM  298
            + V+TTRPDT+ G TY  +A+ H+L    A+T +  A+ +A+ +      +D+A    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVD--AITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  299  EKKGMATGLFATHPLTGEKVPVWVANFVLMEYGTGAVMAVPGHDQRDWEFASKYRLPIKA  358
            EK G+ TG +A +P+ G  +PVW+A++VL  YGTGA+MAVP+HD+RDWEFA ++ L I +
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VILAADGSVPDLSASAMTEKGTLFNSGEFDGLSHEAGFEAIATKLADKGVGERKVNYRLR  418
            V+ ++     ++  +A TE G  +NS+ +DGL   +++  +   L   GVG+ +V YRLR
Sbjct  361  VLEGG-----NVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  419  DWGVSRQRYWGAPIPMVTLEDGSVMPTPEDQLPVVLP--EDVVMDGIT-SPIKADAEWAK  475
            DW  SRQRYWG PIP++  EDG+  + PE +LP+VLP   D+   G   SP+   ++W  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  476  -TIVNGQPALRETDTFDTFMESSWYYARYTCPDYDNGMLDPAAANYWLPVDQYVGGIEHA  534
             T  +G  + RET+T      SSWYY RY  P+  + + D    + WLPVD YVGG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  535  IMHLLYFRFFHKLLRDAGLVNSDEPAKRLLCQGMVLADAFYFTGSNGERNWVSPTDVSVE  594
            ++HLLY RF HK+L D G+V + EP ++L+ QGM+L+ ++      + R     + V+ +
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRG----ALVATD  586

Query  595  RDEKGRITKATDNDGHELVYAGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPAEM  654
            + EK   +    + G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P + 
Sbjct  587  KVEKRDGSFFHVETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  655  TLEWQESGVEGANRFLKRVWRLAFEHTEKGTvaaldvdalnddQKALRRDLHKTISKVSD  714
            ++ W E G+EG+ +FL RV RL    T K                AL +  + T+  V++
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLI---TTKEITEENSG--------ALDKVYNETVKAVTE  694

Query  715  DIGRRQTFNTAIAAIMELMNKLARAPQESGQDRALMQEALLAVVRMLNPFTPHVSFVLWQ  774
            ++++ + FNTAIA +M ++N        + ++  L  +   + V+++ PF+PH++  LWQ
Sbjct  695  QVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  775  ALGGMGD-IDNAPWPQADEAAMVEDSLLVVVQVNGKVRGKITVAANATQEQVQARAAQEH  833
            AL + G+ I   PWP  DE+ +VE+ + +VVQ++GKV++K+ VA + ++E++Q  A  ++
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  834  LVAKYLNGVTIRKVIYVPGKLLNLVV  859
             V   + G  I KVI VP KL+N+V+
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVI  832

1228) leuS in NC_013961


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  539 bits (2033),  Expect = 4e-154, Method: Compositional matrix adjust.
 Identities = 356/866 (42%), Positives = 545/866 (63%), Gaps = 48/866 (5%)

Query  5    YRPEEIESHVQQHWDDKQTFKVIEEEGKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIS  63
            Y    IE+  Q  W D++TFK   + +K K+Y L M+PYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYANIDYMKNQLKLLGFGYDWHR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T  NI   K Q++ LGF+YDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCQPEYYRWEQWFFTKLYEKGLVYKKTSAVNWCPHDMTVLANEQVI-DGCCWRCDSK  182
            E+ T +P+YY+W QW+FTKLYEKGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFVKITDYADELLNDLDKLESWPEQVKTMQRNWIGRSEGVEIEFSVIDSEEK  242
            V RK + QW +KIT YA+ LL+DL+ ++ WPE +K MQRNWIG+S G ++ F V D++  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LGVYTTRPDTFMGVTYLAVAAGHPLASQAAMTNPALADFIAECRNTKVAEADMA----TM  298
            + V+TTRPDT+ G TY  +A+ H+L    A+T +  A+ +A+ +      +D+A    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVD--AITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  299  EKKGMATGLFATHPLTGEKVPVWVANFVLMEYGTGAVMAVPGHDQRDWEFASKYRLPIKA  358
            EK G+ TG +A +P+ G  +PVW+A++VL  YGTGA+MAVP+HD+RDWEFA ++ L I +
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VILAADGSVPDLSASAMTEKGTLFNSGEFDGLSHEAGFEAIATKLADKGVGERKVNYRLR  418
            V+ ++     ++  +A TE G  +NS+ +DGL   +++  +   L   GVG+ +V YRLR
Sbjct  361  VLEGG-----NVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  419  DWGVSRQRYWGAPIPMVTLEDGSVMPTPEDQLPVVLP--EDVVMDGIT-SPIKADAEWAK  475
            DW  SRQRYWG PIP++  EDG+  + PE +LP+VLP   D+   G   SP+   ++W  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  476  -TIVNGQPALRETDTFDTFMESSWYYARYTCPDYDNGMLDPAAANYWLPVDQYVGGIEHA  534
             T  +G  + RET+T      SSWYY RY  P+  + + D    + WLPVD YVGG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  535  IMHLLYFRFFHKLLRDAGLVNSDEPAKRLLCQGMVLADAFYFTGSNGERNWVSPTDVSVE  594
            ++HLLY RF HK+L D G+V + EP ++L+ QGM+L+ ++      + R     + V+ +
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRG----ALVATD  586

Query  595  RDEKGRITKATDNDGHELVYAGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPAEM  654
            + EK   +    + G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P + 
Sbjct  587  KVEKRDGSFFHVETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  655  TLEWQESGVEGANRFLKRVWRLAFEHTEKGTvaaldvdalnddQKALRRDLHKTISKVSD  714
            ++ W E G+EG+ +FL RV RL    T K                AL +  + T+  V++
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLI---TTKEITEENSG--------ALDKVYNETVKAVTE  694

Query  715  DIGRRQTFNTAIAAIMELMNKLARAPQESGQDRALMQEALLAVVRMLNPFTPHVSFVLWQ  774
            ++++ + FNTAIA +M ++N        + ++  L  +   + V+++ PF+PH++  LWQ
Sbjct  695  QVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  775  ALGGMGD-IDNAPWPQADEAAMVEDSLLVVVQVNGKVRGKITVAANATQEQVQARAAQEH  833
            AL + G+ I   PWP  DE+ +VE+ + +VVQ++GKV++K+ VA + ++E++Q  A  ++
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  834  LVAKYLNGVTIRKVIYVPGKLLNLVV  859
             V   + G  I KVI VP KL+N+V+
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVI  832

1229) HICON_04820 in NC_014922


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  539 bits (2033),  Expect = 4e-154, Method: Compositional matrix adjust.
 Identities = 360/866 (42%), Positives = 560/866 (65%), Gaps = 46/866 (5%)

Query  5    YRPDMIEPKVQQYWAENKVFKAIKDESKEKYYCLSMFPYPSGR-LHMGHVRNYTIGDVIS  63
            Y    IEPK Q +WA+N  FK+  D SK K+Y L MFPYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPFGWDAFGLPAEGAAIKNKTAPAKWTYENIAYMKKQLQLLGFGFDWDR  123
            R++R  G NVL+P GWDAFGLPAE  A+     PA  T ENIA  K+Q++ LGF++DWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EIATCKPDYYKWEQWFFTELYKKGLVYKKTSTVNWCPNDETVLANEQV-HEGCCWRCDTP  182
            E+ T  P+YYKW QW+FT LY KGL Y     VNW  +  T +ANE+V  +G   R + P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VEQKEIPQWFIKITDYAEQLLGGLDNLPQWPDMVKTMQRNWIGRSEGVEITFDVADTNEK  242
            V +K + QW +KIT YAE+LL +L+++ +WP+ +K MQRNWIG+S G ++TF V DT+  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  VAVYTTRPDTFYGVSY--LGIaaahplaslaaQNNSELAAFIQEAK-NAKVAEADLATME  299
             +V+TTRPDT++G +Y  L+   A   A  ++++   +A + ++A  ++ +A +DLA  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGMATGLFAIHPLTGEELPIWVANFVLMHYGTGAVMAVPAHDQRDFEFAQKYSLPIKQV  359
            K G+ TG +AI+P+ G E+P+W+A++VL  YGTGA+MAVPAHD+RD EFA++++L   ++
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNL---DI  358

Query  360  IAPLANEEIDLTKQAFVEHGKLVNSAEFDGLDFDGAFNGIADKLEKLGVGKRQVNYRLRD  419
            I+ L   +++    AF E+G  +NS  +DGLD  +A+  + + LE  GVG+ +V YRLRD
Sbjct  359  IPVLEGGNVE--EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMLTLENGDVVPAPMEDLPIILP--EDVVMDGV-KSPIKADPNWAKT  476
            W  SRQRYWG PIP++  E+G   + P  +LP++LP   D+   G   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  TF-NGAPALKETDTFDTFMESSWYYARYTCPQYQNGMLDAEEANYWLPVDQYIGGIEHAT  535
            T  +G  + +ET+T      SSWYY RY  P+  + + D E  + WLPVD Y+GG EHA 
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLLYFRFFHKLLRDAGFVTSDEPADKLLCQGMVLADAFYYTSPTNERIWVSPTQVTLER  595
            +HLLY RF HK+L D G V + EP +KL+ QGM+L+ ++      + R     + V+ ++
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSR----GALVATDK  587

Query  596  DEKGRIIKATDPEGRELVHSGMTKMSKSKNNGIDPQEMVEKYGADTVRLFMMFASPAEMT  655
             EK R     + E  E ++ + +KMSKS +N ++P+++VE+YGADT+R++ MF +P + +
Sbjct  588  VEK-RDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  656  LEWQESGVEGAKRFLGRVWNLVYQYQQNPAKTSLDITALSATQKALRREVHKTIAKVSDD  715
            + W E G+EG+++FL+RV  L+         T+ +IT       AL +  + T+  V+++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLI---------TTKEITE--ENSGALDKVYNETVKAVTEQ  695

Query  716  IGRRQTFNTAIAAVMELMNKLTKASLESDQDRAVMAEALSAVVRMLYPITPHICFELWQA  775
            +++ + FNTAIA +M ++N        ++++  + ++   + V+++ P++PH+  ELWQA
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  776  L-GNESNIDTAEWVKADEAAMVEDEKLIVVQVNGKVRGKVTVATDADEDTVKTIAFADEN  834
            L ++  +I    W   DE+ +VE++  IVVQ++GKV++K+ VA D   + ++ +A+A+E+
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  835  VKKFIDNQHIVKVIYVVGKLLNVVVK  860
            V+  I  ++I+KVI V  KL+N+V+K
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVIK  833

1230) D781_1124 in NC_020064


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  539 bits (2033),  Expect = 4e-154, Method: Compositional matrix adjust.
 Identities = 358/866 (42%), Positives = 557/866 (65%), Gaps = 48/866 (5%)

Query  5    YRPEEIESNVQSHWQEKQTFKVTEDAGKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIS  63
            Y    IE++ Q+ W +++TFK   DA+K K+Y L M+PYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIEYMKNQLKLLGFGYDWDR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NI   K Q++ LGF+YDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EIATCKPDYYRWEQWFFTKLYEKGLVYKKTSAVNWCPHDMTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W QW+FTKLYEKGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITDYADQLLNDLDKLEDWPEQVKTMQRNWIGRSEGVEITFDVDGSDEN  242
            V RK + QW +KIT YA++LL+DL+ + DWPE +K MQRNWIG+S G ++TF V ++D +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  VTVYTTRPDTFMGATYVAVAAGHPLAQQGAVNNPALGDFIEECRNTKVAEADMA----TM  298
             TV+TTRPDT+ GATY  +A+ H+L +  A+  +  ++ + + +      +D+A    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVD--AITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  299  EKKGMATGLYAIHPLSGEKLPIWVANFVLMEYGTGAVMAVPAHDQRDWEFATKYNLPIKA  358
            EK G+ TG YAI+P++G  +P+W+A++VL  YGTGA+MAVPAHD+RDWEFA ++NL I +
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VILNLDGSQPDISGEAMTEKGALFNSGEFDGLDHDAGFNAIADKLVEKGVGQRKVNYRLR  418
            V   L+G+  ++   A TE G  +NS+ +DGLD  +++  + + L   GVG+ +V YRLR
Sbjct  361  V---LEGG--NVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  419  DWGVSRQRYWGAPIPMVTLEDGTVMPTPEDQLPVLLP--EDVVMDGIT-SPIKADVEWAK  475
            DW  SRQRYWG PIP++  EDGT  + PE +LP++LP   D+   G   SP+    +W  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  476  TT-VNGQPALRETDTFDTFMESSWYYARYTCPQYDQGMLDPAAANYWLPVDQYIGGIEHA  534
             T  +G  + RET+T      SSWYY RY  P+  + + D    + WLPVD Y+GG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  535  IMHLMYFRFFHKLMRDAGLVDSDEPAKRLLCQGMVLADAFYYTGNNGERIWVSPVDATIE  594
            ++HL+Y RF HK++ D G+V + EP ++L+ QGM+L+ +  Y ++ G  +        +E
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS--YRDSRGALV----ATDKVE  589

Query  595  RDEKGRITKATDPQGRELVYAGMSKMSKSKNNGIDPQEMVEKYGADTVRLFMMFASPAEM  654
            + + + +   T   G EL   + +KMSKS +N ++P+++VE+YGADT+R++ MF +P + 
Sbjct  590  KRDGSFFHVET---GEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  655  TLEWQESGVEGANRFLKRVWKLAYDHVEKGAVQPLDVASLNDAQKALRRDVHKTIAKVTD  714
            ++ W E G+EG+ +FL RV +L         +   +++  ++   AL +  + T+  VT+
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRL---------ITTKEIT--EENSGALDKVYNETVKAVTE  694

Query  715  DIGRRQTFNTAIAAVMELMNKLGRAPQESEQDRALLQEALLAVVRMLYPFTPHVCFSLWQ  774
            ++++ + FNTAIA +M ++N        ++++  L+ +   + V+++ PF+PH+   LWQ
Sbjct  695  QVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  775  ALGGAGdidvapw-pvaddaaMVEDSKLVVVQVNGKVRAKITVPADASEEQVRERAAEEH  833
            AL ++G+       P  D++ +VE+   +VVQ++GKV+AK+ V+ D S E+++E A  ++
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  834  LVAKYLDGVTIRKVIYVPGKLLNLVV  859
             V   + G  I KVI VP KL+N+V+
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVI  832

1231) Desdi_3025 in NC_019903


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  538 bits (2032),  Expect = 4e-154, Method: Compositional matrix adjust.
 Identities = 360/869 (42%), Positives = 545/869 (63%), Gaps = 79/869 (9%)

Query  5    YLFSEIESRWQKQWVDRKDYKAENHSDKPKYYALAMFPYPSG-NLHMGHVRNYSIVDVIA  63
            Y  + IE++WQ  W D   +K+  ++ KPK+YAL MFPYPSG  LH+GH   Y+  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RFKRMMGFNVLHPIGWDSFGLPAENAAIKNQTPPAEWTWKNIANMKRQLQEMGISYDWDR  123
            RFKR  G NVLHP+GWD+FGLPAE+ A+     PAE T  NIAN KRQ++ +G+SYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EFATCHPDYYKFTQWMFLEFYKHGLVYKRKAAVNWCPSCATVLANEQVV-DGACERCDTE  182
            E  T +P+YYK TQW+F  +Y  GL Y    +VNW    +T +ANE+V+ DG+ ER +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VTKKDLEQWFFKITDYAQVLLDDLEKLKGWPEKVKTMQKNWIGRSEGTEVEFTVENREDK  242
            V +K + QW +KIT YA+ LL+DLE + +WPE +K MQ+NWIG+S G++V F V + +  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  IRVYTTRVDTIFGVSYVVLAPEHPLVQELIAGTEYEQEVQNFVSRMKGLNEIARTSTETE  302
            + V+TTR DT+FG +Y VLAPEH+LV+ + ++ +  + V ++  +    +++ART    E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQ-AEAVADYKRQASLKSDLARTDLAKE  301

Query  303  KEGLFTGAYCLNPYSGERVPIWIANYVLFDYGTGAVMGVPAHDERDFEFATKYKLPIKTV  362
            K G+ TG+Y +NP +G  +P+WIA+YVL  YGTGA+M+VPAHDERD EFA +++L I  V
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  363  ILPEDASVTEKDAPLQVAFTGEGIMVNSGEYDGLKNMDAWDKMSAQAEQDGFGERKVNFR  422
            +  E+++V E       AFT +G+ +NS+  DGL +  A  KM    E +G G+ +V +R
Sbjct  362  L--EGGNVEE------AAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYR  413

Query  423  LRDWLISRQRYWGAPIPMVYCDHCGIvpvpqdqlpvqlpddvvFK---AGENPLTSSESF  479
            LRDWL+SRQRYWG PIP++  ++    +VP+ +LP+ LP    ++   +GE+PL++    
Sbjct  414  LRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDW  473

Query  480  KQTTCPTCGGKARRETDTMDTFMCSSWYFLRYTDPQNSKLPFSKEAADQWMNVDQYVGGV  539
             + T    G K+RRET+TM     SSWY+LRY DP+N+      E   QW+ VD YVGG 
Sbjct  474  LEVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGA  532

Query  540  EHAILHLLYSRFFTKALRDFGYLKVDEPFENLLTQGMV----------CL----------  579
            EHA+LHLLY+RF  K L D+G +   EPF++L+ QGM+           L          
Sbjct  533  EHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRD  592

Query  580  --------------GGAKMSKSKGNVVSPEEIISKYGADTARLFILFAAPPDRDLEWSDQ  625
                          + AKMSKS  NVV+P++++ +YGADT R++ +F +P D  + WS++
Sbjct  593  GSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEE  652

Query  626  GVEGCYRFLNRVWRLAAQYEDVLKGQSSGEAASVQGRNFGELDKAAKDMRRQTHQAIQRV  685
            G+EG  +FL+RV RL +             +  +   N G LDK  ++  +   + ++++
Sbjct  653  GLEGSRKFLDRVYRLIT-------------TKEITEENSGALDKVYNETVKAVTEQVDQM  699

Query  686  TSDIGVRFNFNTAVSSIMELVNALYLYKEQPNVNVAAASEAMESVLLLLSPFAPHMTEEI  745
                    +FNTA++ +M +VNA       +N +    S+   + + L++PFAPH+ EE+
Sbjct  700  --------KFNTAIAQLMVFVNA-------ANKEDKLFSDYAKGFVQLIAPFAPHLGEEL  744

Query  746  WSQL-GHEESIHRMEWPKVDERALVQDEVTVVLQVNGKLKDRIQVSAQISAEELEAQVRL  804
            W  L +  ESI  + WP  DE  LV+++V +V+Q++GK+K ++ V+ ++S EEL+     
Sbjct  745  WQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALA  804

Query  805  LPKLEEWTQGKQIVKIITVPGKLINVVVK  833
              K++    GK+I+K+I+VP KL+N+V+K
Sbjct  805  NEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

1232) leuS in NC_016781


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  538 bits (2032),  Expect = 5e-154, Method: Compositional matrix adjust.
 Identities = 353/742 (48%), Positives = 510/742 (69%), Gaps = 68/742 (9%)

Query  231  LVYRSHSMVNWCPGLGTVLANEEVTADGRSERGNFPVFRKNLSQWMMRITAYSDRLIDDL  290
            L Y ++  VNW   LGT +ANEEV +DG SERG +PV RK + QWM++ITAY++RL++DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  291  DALDWPDKVKSMQRNWIGRSRGAEVDFDV--LGHTITVFTTRPDTLFGASYMVLAPEHEL  348
            + +DWP+ +K MQRNWIG+S GA+V F V   +  +TVFTTRPDTLFGA+Y VLAPEH L
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  349  VDALVAAGTNSYDGVDPRWTFEQSCPADAVKAYRASIAAKSDLERQE-NKEKTGVYLGVN  407
            VDA+ +++                  A+AV  Y+   + KSDL R +  KEKTGV  G  
Sbjct  268  VDAITTSD-----------------QAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSY  310

Query  408  AVNPVNGESIPVFIGDYVLTGYGTGAIMAVPAHDTRDYEFATEFGLPIREVVAGGNVAEE  467
            A+NPVNG  +PV I+DYVL++YGTGAIMAVPAHD RD EFA +F L I  V+ GGNV E 
Sbjct  311  AINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEA  370

Query  468  AYTESGVAVNSANDEGLDINGLDKQEAIARVIEWLVDKQKGSEKIQYKLRDWLFARQRYW  527
            A+TE G+ +NS       ++GLDK  AIA+++EWL     G+E++ Y+LRDWLF+RQRYW
Sbjct  371  AFTEDGLHINSDF-----LDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYW  425

Query  528  GEPFPVVYDADGVAHALPESMLPVELPEVEDYKPVSFDPDDADSEPQPPLAKATEWTQVE  587
            GEP+P++   DG + A+PES LP+ LP   D +P         +  ++PLA+ T+W +V 
Sbjct  426  GEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTDWLEVT  477

Query  588  LDLGDGLKTYTRDTNVMPQWAGSSWYQLRYIDPTNNKQFCDIENERYWTGPRGENdlggv  647
             +  DG+K   R+TN MPQWAGSSWY LRYIDP N  ++ D E  + W           V
Sbjct  478  RE--DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLP---------V  525

Query  648  dlyvggvEHAVLHLLYSRFWHKVLFDLGYVTSGEPYRRLFNQGYIQAFAYTDSRGVYVPA  707
            D+YVGG EHAVLHLLY+RFWHKVL+DLG V + EP+++LFNQG I + +Y DSRG  V++
Sbjct  526  DIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVAT  585

Query  708  AEVEEKDGKFFY--QGEEVNQEYGKMGKSLKNAVAPDEICSDFGADTLRVYEMAMGPLDT  765
              VE +DG FF    GEE++Q  +KM+KSLKN V PD++  ++GADTLRVYEM MGPLD+
Sbjct  586  DKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  766  SRPWATKDVIGAHRFLQRLWRLVVSEDDGSVVVTDAGLADDDLKQLHRTIAGMRDDYEGL  825
            S +W+  ++ G+++FL+R+ RL+ + +   +   ++G  D   K  + T+ ++ ++ + +
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLITTKE---ITEENSGALD---KVYNETVKAVTEQVDQM  699

Query  826  RINTVVAKAIEYVNYLTK------NYAKGAPRAAVEPLVIMVAPVAPHIAEELWKRL-GH  878
            ++NT +A+ + +VN   K      +YAKG        +V ++AP APH++EELW+ L + 
Sbjct  700  KFNTAIAQLMVFVNAANKEDKLFSDYAKG--------FVQLIAPFAPHLGEELWQALTAS  751

Query  879  EETITFVAFPDYDEKWLVDDEVEMPIQINGKVRARIMVPADATQDQIVEIALAEPTVQSH  938
             E+I++V+ P YDE  LV+++VE+ +QI+GKV+A+++V+ D +++++ E+ALA+  VQ++
Sbjct  752  GESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAE  811

Query  939  LEGKNLFKQIVVPGRMVNLVIK  960
            + GK+++K I VP ++VN+VIK
Sbjct  812  IAGKDIIKVIAVPNKLVNIVIK  833


 Score =  141 bits (520),  Expect = 2e-34, Method: Compositional matrix adjust.
 Identities = 81/149 (55%), Positives = 106/149 (72%), Gaps = 10/149 (6%)

Query  28   GDIERTWQQFWIDNGTFNAPNPVGDLAVAGQELPEDKLFVQDMFPYPSGAGLHVGHPLGY  87
              IE  WQ FW DN TF++          G + +  K++  DMFPYPSGAGLHVGHP GY
Sbjct  7    TAIEPKWQAFWADNHTFKT----------GTDASKPKFYALDMFPYPSGAGLHVGHPEGY  56

Query  88   IATDVFARFNRMLGKNVLHTLGYDAFGLPAEQYAIQTGTHPRATTMSNIANMQRQLSALG  147
             ATD+++RF+R  G NVLH +G DAFGLPAEQYA++TG +P   T  NIAN +RQ++ALG
Sbjct  57   TATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALG  116

Query  148  LGHDPRRSVATTDPEFYKWTQWIFLQIFN  176
            ++ D  R V TTDP++YKWTQWIF ++++
Sbjct  117  FSYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1233) leuS in NC_014329


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  538 bits (2032),  Expect = 5e-154, Method: Compositional matrix adjust.
 Identities = 353/742 (48%), Positives = 510/742 (69%), Gaps = 68/742 (9%)

Query  231  LVYRSHSMVNWCPGLGTVLANEEVTADGRSERGNFPVFRKNLSQWMMRITAYSDRLIDDL  290
            L Y ++  VNW   LGT +ANEEV +DG SERG +PV RK + QWM++ITAY++RL++DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  291  DALDWPDKVKSMQRNWIGRSRGAEVDFDV--LGHTITVFTTRPDTLFGASYMVLAPEHEL  348
            + +DWP+ +K MQRNWIG+S GA+V F V   +  +TVFTTRPDTLFGA+Y VLAPEH L
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  349  VDALVAAGTNSYDGVDPRWTFEQSCPADAVKAYRASIAAKSDLERQE-NKEKTGVYLGVN  407
            VDA+ +++                  A+AV  Y+   + KSDL R +  KEKTGV  G  
Sbjct  268  VDAITTSD-----------------QAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSY  310

Query  408  AVNPVNGESIPVFIGDYVLTGYGTGAIMAVPAHDTRDYEFATEFGLPIREVVAGGNVAEE  467
            A+NPVNG  +PV I+DYVL++YGTGAIMAVPAHD RD EFA +F L I  V+ GGNV E 
Sbjct  311  AINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEA  370

Query  468  AYTESGVAVNSANDEGLDINGLDKQEAIARVIEWLVDKQKGSEKIQYKLRDWLFARQRYW  527
            A+TE G+ +NS       ++GLDK  AIA+++EWL     G+E++ Y+LRDWLF+RQRYW
Sbjct  371  AFTEDGLHINSDF-----LDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYW  425

Query  528  GEPFPVVYDADGVAHALPESMLPVELPEVEDYKPVSFDPDDADSEPQPPLAKATEWTQVE  587
            GEP+P++   DG + A+PES LP+ LP   D +P         +  ++PLA+ T+W +V 
Sbjct  426  GEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTDWLEVT  477

Query  588  LDLGDGLKTYTRDTNVMPQWAGSSWYQLRYIDPTNNKQFCDIENERYWTGPRGENdlggv  647
             +  DG+K   R+TN MPQWAGSSWY LRYIDP N  ++ D E  + W           V
Sbjct  478  RE--DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLP---------V  525

Query  648  dlyvggvEHAVLHLLYSRFWHKVLFDLGYVTSGEPYRRLFNQGYIQAFAYTDSRGVYVPA  707
            D+YVGG EHAVLHLLY+RFWHKVL+DLG V + EP+++LFNQG I + +Y DSRG  V++
Sbjct  526  DIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVAT  585

Query  708  AEVEEKDGKFFY--QGEEVNQEYGKMGKSLKNAVAPDEICSDFGADTLRVYEMAMGPLDT  765
              VE +DG FF    GEE++Q  +KM+KSLKN V PD++  ++GADTLRVYEM MGPLD+
Sbjct  586  DKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  766  SRPWATKDVIGAHRFLQRLWRLVVSEDDGSVVVTDAGLADDDLKQLHRTIAGMRDDYEGL  825
            S +W+  ++ G+++FL+R+ RL+ + +   +   ++G  D   K  + T+ ++ ++ + +
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLITTKE---ITEENSGALD---KVYNETVKAVTEQVDQM  699

Query  826  RINTVVAKAIEYVNYLTK------NYAKGAPRAAVEPLVIMVAPVAPHIAEELWKRL-GH  878
            ++NT +A+ + +VN   K      +YAKG        +V ++AP APH++EELW+ L + 
Sbjct  700  KFNTAIAQLMVFVNAANKEDKLFSDYAKG--------FVQLIAPFAPHLGEELWQALTAS  751

Query  879  EETITFVAFPDYDEKWLVDDEVEMPIQINGKVRARIMVPADATQDQIVEIALAEPTVQSH  938
             E+I++V+ P YDE  LV+++VE+ +QI+GKV+A+++V+ D +++++ E+ALA+  VQ++
Sbjct  752  GESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAE  811

Query  939  LEGKNLFKQIVVPGRMVNLVIK  960
            + GK+++K I VP ++VN+VIK
Sbjct  812  IAGKDIIKVIAVPNKLVNIVIK  833


 Score =  141 bits (520),  Expect = 2e-34, Method: Compositional matrix adjust.
 Identities = 81/149 (55%), Positives = 106/149 (72%), Gaps = 10/149 (6%)

Query  28   GDIERTWQQFWIDNGTFNAPNPVGDLAVAGQELPEDKLFVQDMFPYPSGAGLHVGHPLGY  87
              IE  WQ FW DN TF++          G + +  K++  DMFPYPSGAGLHVGHP GY
Sbjct  7    TAIEPKWQAFWADNHTFKT----------GTDASKPKFYALDMFPYPSGAGLHVGHPEGY  56

Query  88   IATDVFARFNRMLGKNVLHTLGYDAFGLPAEQYAIQTGTHPRATTMSNIANMQRQLSALG  147
             ATD+++RF+R  G NVLH +G DAFGLPAEQYA++TG +P   T  NIAN +RQ++ALG
Sbjct  57   TATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALG  116

Query  148  LGHDPRRSVATTDPEFYKWTQWIFLQIFN  176
            ++ D  R V TTDP++YKWTQWIF ++++
Sbjct  117  FSYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1234) leuS in NC_007498


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  538 bits (2031),  Expect = 5e-154, Method: Compositional matrix adjust.
 Identities = 362/832 (44%), Positives = 526/832 (64%), Gaps = 37/832 (4%)

Query  5    YDAGGIEGKWQKRWEQDRTFKAKEKDAREKYYLLEMFPYPSGR-IHMGHVRNYSIGDVVA  63
            YD  +IE KWQ  W +++TFK+    ++ K+Y L+MFPYPSG  +H+GH   Y+  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RFKRLQGYNVLHPMGWDAFGMPAENAAIQHKTHPGKWTYENIDNMRAQLKKMGFSYDWDR  123
            RFKR QG NVLHPMGWDAFG+PAE+ A++   +P+  T ENI N + Q++ +GFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVATCHPEYYRWEQLIFLKMLEKGLAYKKSSFVNWCSECQTVLANEQVENDACW-RCGTV  182
            EV T +P+YY+W Q IF K+ EKGLAY     VNW  E  T +ANE+V  D+   R G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VEQKELEQWFFKITDYAQELLDDTSKLSGWPEPVLTMQRNWIGRSTGCEIDFPVADSDLK  242
            V +K + QW +KIT YA+ LL+D   + +WPE++  MQRNWIG+STG ++ F V D+D  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  IKVFTTRQDTLYGATFMSLAAEHPLAMELVSAECKAEVEAFIARVRTQDKAKRTSDDFVK  302
            + VFTTR DTL+GAT+  LA+EH+L   + +++    V  +  +   +    RT     K
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEK  302

Query  303  EGVFTGSYGINPVNGRRIPIYLANFVLMDYGTGAVMAVPTHDQRDFDFARKYDIPMIVVI  362
             GV TGSY+INPVNG+ +P+ +A++VL  YGTGA+MAVP+HD+RD +FA+++++ +I V+
Sbjct  303  TGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL  362

Query  363  QPEDQTLDPATMTEAWTAPGVLVNSAPFDGLDNESAKEKIAAHLEEQGVGRKTVNYRLRD  422
            +  +  ++ A+ TE     G+ +NS  +DGLD+ SA  K+   LE +GVG   V YRLRD
Sbjct  363  EGGN--VEEAAFTED----GLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  423  WGVSRQRYWGTPIPIIY--CPACGIvpvpeedlpvllpMDVEISGEGGSPLARHQEFLKV  480
            W  SRQRYWG PIPII     +   VP +E  L + +  D+  SG G SPLA   + L V
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  481  TCPTCGGDARRETDTFDTFVESSWYFARYTCPRFEQGPVDRATVDHWLPVDQYIGGIEHA  540
            T    G  +RRET+T      SSWY+ RY  P+  +   D   + +WLPVD Y+GG EHA
Sbjct  477  TRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  541  VMHLLYARFFTKVMRDLGMMAHDEPFKNLLTQGMVCMETASCPEHGWLFPEQVVEGK---  597
            V+HLLYARF  KV+ DLG+++  EPF++L+ QGM+ + T+    +G L + + VE +   
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMI-LGTSYRDSRGALVATDKVEKRDGS  594

Query  598  --CVLCGATAQTGRNEKMSKSKKNVVDPDKLILSYGADTARLFSLFAAPPEKDLEWNEQG  655
               V  G   + +   KMSKS KNVV+PD ++  YGADT R++ +F +P +  + W+E+G
Sbjct  595  FFHVETGEELEQAPA-KMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEG  653

Query  656  VEGCYRFLHRVWRAVYDNLEMISGVAVPASVDGAARNLRRQVHATIKKVTGDIDGRFHFN  715
            +EG  +FL+RV R       +I+   +     GA   L +  + T+K VT ++D +  FN
Sbjct  654  LEGSRKFLDRVYR-------LITTKEITEENSGA---LDKVYNETVKAVTEQVD-QMKFN  702

Query  716  TAIASVMELVNAIYGFEAKAQYPGVMREALEATVRLLAPFVPHVCEELWACLGHEG-GLE  774
            TAIA +M +VNA      K +   +  +   + V+L+APF PH+ EELW  L   G ++ 
Sbjct  703  TAIAQLMVFVNA----ANKED--KLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESIS  756

Query  775  AAGWPAWDEEALVEDEKTIVVQVNGKVRGKLTIAADADNDTVQQAALKADNV  826
               WP+ DE  LVE++  IVVQ++GKV++KL +A D   + +Q+ AL  ++V
Sbjct  757  YVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKV  808

1235) leuS in NC_018531


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  538 bits (2032),  Expect = 5e-154, Method: Compositional matrix adjust.
 Identities = 354/855 (42%), Positives = 550/855 (65%), Gaps = 66/855 (7%)

Query  25   YSFAAMEAKWPQVWEDLKVFTPADDGSRERRYVLDMFPYPSG-DLHMGHAEAFAMGDVVA  83
            Y  +A+E+KW   W D   F  + D+S+ + Y LDMFPYPSG +LH+GH+E+++  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  84   RYLRQKGFDVLHPIGWDSFGLPAENAAIKRNAHPSEWTYANIDTQAASFKRYAISADWSR  143
            R+ R +G +VLHP+GWD+FGLPAE+ A+    +P+E T  NI      ++  ++S DW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  144  RLHTSDPEYYRWTQWLFKRFYERGLAYRKDSPVNWCPKDLTVLANEQVV-NGACERCGTP  202
             ++T+DP+YY+WTQW+F ++YE+GLAY  + PVNW     T +ANE+V+ +G+ ER G P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  203  VTKKSLNQWYFKITDYADRLLEDMDQLQGHWPERVLAMQRNWIGRSEGAHVRFVIEATAD  262
            V +K++ QW +KIT YA+RLLED+++++  WPE +  MQRNWIG+S GA+V F +  T  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD--WPESIKDMQRNWIGKSTGANVTFKVKDT--  239

Query  263  RAEREVTVFTTRPDTLYGATFFvvaadahlaldlvTPEQHDELMAYREKVKALSEIERQS  322
              +++ TVFTTRPDTL+GAT+ V+A++  L   + T++Q + +  Y+ +    S++ R  
Sbjct  240  --DKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTD  297

Query  323  TEREKTGVFTGRYAINPLNGEKLPVWAADYVLADYGTGAIMAVPAHDQRDLDFARTFGLP  382
              +EKTGV TG YAINP+NG  +PVW ADYVLA YGTGAIMAVPAHD+RD +FA+ F L 
Sbjct  298  LAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLD  357

Query  383  VRAVLDTGDEDPAETGVATAGEGTLKNSGELDGLSKSEGIPAAIEILEKLGTGEKFVNFR  442
            + +VL+ G+ + A    A + +G   NS+ LDGL K+ +I+  +E LE  G G+  V +R
Sbjct  358  IIPVLEGGNVEEA----AFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYR  413

Query  443  LRDWLLSRQRFWGTPIPIIHCGECGEVPVPDDQLPVRLP--DDLRGEALSPKGTSPLAAA  500
            LRDWL+SRQR+WG PIPIIH  +    +VP+ +LP+ LP   D+R    S  G SPLA  
Sbjct  414  LRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRP---SGTGESPLANV  470

Query  501  VEWVNVECPNCGRAAQRDTDTMDTFVDSSWYFLRFVSPDYTEGPFDPEKINNWMPVGQYV  560
             +W++V   +  + ++R+T+TM    +SSWY+LR++ P+ TE   D E +++W+PV+ YV
Sbjct  471  TDWLEVTREDGVK-GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYV  529

Query  561  GGVEHAILHLLYARFFTKVIKDIGLIEANEPFSALLNQGQVLNGG---------------  605
            GG EHA+LHLLYARF  KV+ D+G++ ++EPF  L+NQG +L  +               
Sbjct  530  GGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVE  589

Query  606  -------------------KAMSKSLGNGVDLGEQLDKFGVDAVRLTMVFASPPEDDVDW  646
                                 MSKSL N V+ ++ ++++G D++R+  +F +P +  + W
Sbjct  590  KRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAW  649

Query  647  ADVSPSGSAKFLARAWRLGQDVSSEPGVDPATGDRALRTVTHKTIADAAELLDNNKFNVV  706
            ++ +  GS KFL R  RL   +++    +  +G  AL  V + T+   +E +D+ KFN  
Sbjct  650  SEEGLEGSRKFLDRVYRL---ITTKEITEENSG--ALDKVYNETVKAVTEQVDQMKFNTA  704

Query  707  VARLMELVNATRKTIDSGAGaadpavreaveavavILSLFAPYTAEDLWNTLGHPA-SVA  765
            +A+LM +VNA+ K         D    +   +   +++ FAP  +E+LW++L  ++ S++
Sbjct  705  IAQLMVFVNAANKE--------DKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESIS  756

Query  766  NAGWPKHDDallvqdtvtavvqvQGKVRDRLDVSPDITEDALRELALASENVQRALDGRG  825
               WP  D++ LV++ V  VVQ++GKV+ +L V+ D++ + L+E+ALA+E+VQ  + G++
Sbjct  757  YVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKD  816

Query  826  IRTVIVRAPKLVNIV  840
            I  VI  + KLVNIV
Sbjct  817  IIKVIAVPNKLVNIV  831

1236) NT01EI_2936 in NC_012779


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  538 bits (2031),  Expect = 5e-154, Method: Compositional matrix adjust.
 Identities = 356/866 (42%), Positives = 557/866 (65%), Gaps = 48/866 (5%)

Query  5    YRPEDIESHVQRHWDEQKTFQVTEDAGKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIS  63
            Y    IE+  Q  W ++ TF+   DA+K K+Y L M+PYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYANIDYMKNQLKLLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T  NI   K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EIATCKPDYYRWEQWFFTKLYEKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDSK  182
            E+ T  P+YY+W QW+FTKLYEKGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITDYADQLLNDLDRLEEWPEQVKTMQRNWIGRSEGVEITFHVADRDDT  242
            V RK + QW +KIT YA++LL+DL+ + +WPE +K MQRNWIG+S G ++TF V D D  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  FAVYTTRPDTFMGVSYlaiaaahplaqqaaTGNPALTQFIDECKNTKVAEADMA----TM  298
            F+V+TTRPDT+ G +Y  +A+ H+L +  +T++ A  + + + K      +D+A    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQA--EAVADYKRQASLKSDLARTDLAK  300

Query  299  EKKGMATGLYAIHPLNGERLPIWVANFVLMDYGTGAVMSVPAHDQRDWEFATRYDLPMKP  358
            EK G+ TG YAI+P+NG  +P+W+A++VL  YGTGA+M+VPAHD+RDWEFA +++L + P
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VILTADGQAPDIRAAAMTDKGVLFNSGEFDGLDFSAAFDAVANRLIAAGVGERKVNYRLR  418
            V+     ++ ++  AA T+ G+ +NS+ +DGLD ++A+  + ++L A GVG+ +V YRLR
Sbjct  361  VL-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  419  DWGVSRQRYWGAPIPMMTLEDGSVIPTPEEQLPVILP--EDVVMNGIT-SPIKADPSWAK  475
            DW  SRQRYWG PIP++  EDG+  + PE +LP++LP   D+  +G   SP+     W  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  476  TT-VNGQPALRETDTFDTFMESSWYYARYTCPQFDQGMLDPQAANYWLPVDQYVGGIEHA  534
             T  +G  + RET+T      SSWYY RY  P+  + + D +  + WLPVD YVGG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  535  IMHLMYFRFFHKLMRDAGLVDSDEPAKRLLCQGMVLADAFYYTGTNGERNWVSPVDVTVE  594
            ++HL+Y RF HK++ D G+V + EP ++L+ QGM+L+ +  Y ++ G         V+ +
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS--YRDSRGAL-------VATD  586

Query  595  RDDKGRITQATDRDGRELVYAGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPAEM  654
            + +K   +      G EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P + 
Sbjct  587  KVEKRDGSFFHVETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  655  TLEWQESGVEGANRFLKRVWKLAFDHQQKGLASALDLTALNDDQKALRRDLHKTIAKVSD  714
            ++ W E G+EG+ +FL RV +         L ++ ++T  +++  AL +  + T+  V++
Sbjct  646  SIAWSEEGLEGSRKFLDRVYR---------LITTKEIT--EENSGALDKVYNETVKAVTE  694

Query  715  DIGRRQTFNTAIAAVMELMNKLTRAPQESEQDRALMQEALLAVVRMLYPFTPHVCFTLWR  774
            ++++ + FNTAIA +M ++N        ++++  L  +   + V+++ PF+PH+   LW+
Sbjct  695  QVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  775  ALGGAGD-IDTAPWPVADDAAMVEDSKLIVVQVNGKVRGKITVAADASEEQVRALAAQEP  833
            AL ++G+ I   PWP  D++ +VE+   IVVQ++GKV++K+ VA D S E+++ +A  + 
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  834  LVAKYLDGVTVRKVIFVPGKLLNLVV  859
             V   + G  + KVI VP KL+N+V+
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVI  832

1237) leuS in NC_017300


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  538 bits (2032),  Expect = 6e-154, Method: Compositional matrix adjust.
 Identities = 353/742 (48%), Positives = 510/742 (69%), Gaps = 68/742 (9%)

Query  224  LVYRSHSMVNWCPGLGTVLANEEVTADGRSERGNFPVFRKNLSQWMMRITAYSDRLIDDL  283
            L Y ++  VNW   LGT +ANEEV +DG SERG +PV RK + QWM++ITAY++RL++DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  284  DALDWPDKVKSMQRNWIGRSRGAEVDFDV--LGHTITVFTTRPDTLFGASYMVLAPEHEL  341
            + +DWP+ +K MQRNWIG+S GA+V F V   +  +TVFTTRPDTLFGA+Y VLAPEH L
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  342  VDALVAAGTNSYDGVDPRWTFEQSCPADAVKAYRASIAAKSDLERQE-NKEKTGVYLGVN  400
            VDA+ +++                  A+AV  Y+   + KSDL R +  KEKTGV  G  
Sbjct  268  VDAITTSD-----------------QAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSY  310

Query  401  AVNPVNGESIPVFIGDYVLTGYGTGAIMAVPAHDTRDYEFATEFGLPIREVVAGGNVAEE  460
            A+NPVNG  +PV I+DYVL++YGTGAIMAVPAHD RD EFA +F L I  V+ GGNV E 
Sbjct  311  AINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEA  370

Query  461  AYTESGVAVNSANDEGLDINGLDKQEAIARVIEWLVDKQKGSEKIQYKLRDWLFARQRYW  520
            A+TE G+ +NS       ++GLDK  AIA+++EWL     G+E++ Y+LRDWLF+RQRYW
Sbjct  371  AFTEDGLHINSDF-----LDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYW  425

Query  521  GEPFPVVYDADGVAHALPESMLPVELPEVEDYKPVSFDPDDADSEPQPPLAKATEWTQVE  580
            GEP+P++   DG + A+PES LP+ LP   D +P         +  ++PLA+ T+W +V 
Sbjct  426  GEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTDWLEVT  477

Query  581  LDLGDGLKTYTRDTNVMPQWAGSSWYQLRYIDPTNNKQFCDIENERYWTGPRGENdlggv  640
             +  DG+K   R+TN MPQWAGSSWY LRYIDP N  ++ D E  + W           V
Sbjct  478  RE--DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLP---------V  525

Query  641  dlyvggvEHAVLHLLYSRFWHKVLFDLGYVTSGEPYRRLFNQGYIQAFAYTDSRGVYVPA  700
            D+YVGG EHAVLHLLY+RFWHKVL+DLG V + EP+++LFNQG I + +Y DSRG  V++
Sbjct  526  DIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVAT  585

Query  701  AEVEEKDGKFFY--QGEEVNQEYGKMGKSLKNAVAPDEICSDFGADTLRVYEMAMGPLDT  758
              VE +DG FF    GEE++Q  +KM+KSLKN V PD++  ++GADTLRVYEM MGPLD+
Sbjct  586  DKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  759  SRPWATKDVIGAHRFLQRLWRLVVSEDDGSVVVTDAGLADDDLKQLHRTIAGMRDDYEGL  818
            S +W+  ++ G+++FL+R+ RL+ + +   +   ++G  D   K  + T+ ++ ++ + +
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLITTKE---ITEENSGALD---KVYNETVKAVTEQVDQM  699

Query  819  RINTVVAKAIEYVNYLTK------NYAKGAPRAAVEPLVIMVAPVAPHIAEELWKRL-GH  871
            ++NT +A+ + +VN   K      +YAKG        +V ++AP APH++EELW+ L + 
Sbjct  700  KFNTAIAQLMVFVNAANKEDKLFSDYAKG--------FVQLIAPFAPHLGEELWQALTAS  751

Query  872  EETITFVAFPDYDEKWLVDDEVEMPIQINGKVRARIMVPADATQDQIVEIALAEPTVQSH  931
             E+I++V+ P YDE  LV+++VE+ +QI+GKV+A+++V+ D +++++ E+ALA+  VQ++
Sbjct  752  GESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAE  811

Query  932  LEGKNLFKQIVVPGRMVNLVIK  953
            + GK+++K I VP ++VN+VIK
Sbjct  812  IAGKDIIKVIAVPNKLVNIVIK  833


 Score =  141 bits (520),  Expect = 2e-34, Method: Compositional matrix adjust.
 Identities = 81/149 (55%), Positives = 106/149 (72%), Gaps = 10/149 (6%)

Query  21   GDIERTWQQFWIDNGTFNAPNPVGDLAVAGQELPEDKLFVQDMFPYPSGAGLHVGHPLGY  80
              IE  WQ FW DN TF++          G + +  K++  DMFPYPSGAGLHVGHP GY
Sbjct  7    TAIEPKWQAFWADNHTFKT----------GTDASKPKFYALDMFPYPSGAGLHVGHPEGY  56

Query  81   IATDVFARFNRMLGKNVLHTLGYDAFGLPAEQYAIQTGTHPRATTMSNIANMQRQLSALG  140
             ATD+++RF+R  G NVLH +G DAFGLPAEQYA++TG +P   T  NIAN +RQ++ALG
Sbjct  57   TATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALG  116

Query  141  LGHDPRRSVATTDPEFYKWTQWIFLQIFN  169
            ++ D  R V TTDP++YKWTQWIF ++++
Sbjct  117  FSYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1238) leuS in NC_022223


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  538 bits (2030),  Expect = 6e-154, Method: Compositional matrix adjust.
 Identities = 377/866 (44%), Positives = 571/866 (66%), Gaps = 49/866 (5%)

Query  52   YNPQDIEQKVQQHWDDNKTFVVSEDPNKEKFYCLSMFPYPSGR-LHMGHVRNYTIGDVVS  110
            Y+   IE K Q  W DN TF  + D++K KFY L MFPYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  111  RFQRLQGKNVMQPIGWDAFGLPAENAAVKNKTAPAPWTYENIQYMKNQLKLLGFGYDWSR  170
            RF+R QG NV++P+GWDAFGLPAE+ A+     PA  T ENI   K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  171  EFATCTPEYYRWEQEFFTKLYQKGLVYKKTSSVNWCPNDQTVLANEQV-EDGCCWRCDTP  229
            E  T  P+YY+W Q +FTKLY+KGL Y    +VNW  +  T +ANE+V  DG   R + P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  230  VEQKEIPQWFIKITAYAQELLDDLENLEGWPEMVKTMQRNWIGRSEGVELKFGV-NGHSD  288
            V +K + QW +KITAYA+ LL+DLE+++ WPE +K MQRNWIG+S G ++ F V + + D
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  289  LDVYTTRPDTLMGVTYVGIAAGHPL--ATIAAQNNPALASFIDECK-NTKVAEAELATME  345
            + V+TTRPDTL G TY  +A+ H+L  A  ++++  A+A +  +   ++ +A ++LA  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  346  KKGMDTGLTAIHPLNGREVPIYIANFVLMDYGTGAVMAVPAHDQRDFEFATKYGLDIIPV  405
            K G+ TG  AI+P+NG+E+P+ IA++VL  YGTGA+MAVPAHD+RD EFA ++ LDIIPV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  406  IKPEDGSEVDVSSAAYTEKGVLFGSGEFDGLafqaafdaiaakleaegkgkkTVNFRLRD  465
            +   +G++V+   AA+TE G+ + S+ +DGL   +A+  +   LEAEG G+  V +RLRD
Sbjct  362  L---EGGNVE--EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  466  WGVSRQRYWGAPIPMVTTEDGQVHPVPIDQLPVILP--EDVVMDGVT-SPIKADKEWAKT  522
            W  SRQRYWG PIP++  EDG   +VP  +LP++LP   D+   G   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  523  TF-NGEPALRETDTFDTFMESSWYYARYCSPQADDIL-DPAKANYWLPVDQYIGGIEHAC  580
            T  +G  + RET+T      SSWYY RY  P+  + L D    + WLPVD Y+GG EHA 
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  581  MHLLYSRFFHKLLRDAGYVTSDEPFKQLLCQGMVLADAFYHTNEKGTKEWVAPTDVKVER  640
            +HLLY+RF HK+L D G V + EPF++L+ QGM+L+ ++   + +G+   + +TD KVE+
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY--RDSRGA---LVATD-KVEK  590

Query  641  DGKGRITQAVDNQGRNVEHSGMIKMSKSKNNGIDPQEMVDKYGADTVRLFMMFASPADMT  700
             + G + +   + G ++E++   KMSKS +N ++P+++V++YGADT+R++ MF +P D +
Sbjct  591  RD-GSFFHV--ETGEELEQAP-AKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  701  LEWQESGVEGANRFLKRVWKLVAEHSAKGVAEAVDSASLTGEQKALRRDVHKTIAKVTDD  760
            + W E G+EG+ +FL RV +L+   ++K ++E   +        AL +  + T+  VT++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLI---TTKEITEENSG--------ALDKVYNETVKAVTEQ  695

Query  761  IARRQTFNTAIAAIMELMNKLTKASQESVQDRAILDEALKAVVSMLYPITPHISFELWNA  820
            + + + FNTAIA +M ++N   K  +       ++ +  K+ V ++ P++PH++ ELW+A
Sbjct  696  VDQMK-FNTAIAQLMVFVNAANKEDK-------LFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  821  LGESD--VDNTVWPTYDESALVEDEKLIVLQVNGKLRGKLTVAADASKDQVEALGLADEN  878
            L  S+  +    WP+YDES LVE++  IV+Q++GK+++KL VA D S+++++ ++LA+E+
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  879  VMKFTDGLTVRKVIYVPGKLLNIVAN  904
            V     G  + KVI VP KL+NIV +
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVIK  833

1239) VAA_01093 in NC_015633


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  538 bits (2030),  Expect = 6e-154, Method: Compositional matrix adjust.
 Identities = 377/866 (44%), Positives = 571/866 (66%), Gaps = 49/866 (5%)

Query  52   YNPQDIEQKVQQHWDDNKTFVVSEDPNKEKFYCLSMFPYPSGR-LHMGHVRNYTIGDVVS  110
            Y+   IE K Q  W DN TF  + D++K KFY L MFPYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  111  RFQRLQGKNVMQPIGWDAFGLPAENAAVKNKTAPAPWTYENIQYMKNQLKLLGFGYDWSR  170
            RF+R QG NV++P+GWDAFGLPAE+ A+     PA  T ENI   K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  171  EFATCTPEYYRWEQEFFTKLYQKGLVYKKTSSVNWCPNDQTVLANEQV-EDGCCWRCDTP  229
            E  T  P+YY+W Q +FTKLY+KGL Y    +VNW  +  T +ANE+V  DG   R + P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  230  VEQKEIPQWFIKITAYAQELLDDLENLEGWPEMVKTMQRNWIGRSEGVELKFGV-NGHSD  288
            V +K + QW +KITAYA+ LL+DLE+++ WPE +K MQRNWIG+S G ++ F V + + D
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  289  LDVYTTRPDTLMGVTYVGIAAGHPL--ATIAAQNNPALASFIDECK-NTKVAEAELATME  345
            + V+TTRPDTL G TY  +A+ H+L  A  ++++  A+A +  +   ++ +A ++LA  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  346  KKGMDTGLTAIHPLNGREVPIYIANFVLMDYGTGAVMAVPAHDQRDFEFATKYGLDIIPV  405
            K G+ TG  AI+P+NG+E+P+ IA++VL  YGTGA+MAVPAHD+RD EFA ++ LDIIPV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  406  IKPEDGSEVDVSSAAYTEKGVLFGSGEFDGLafqaafdaiaakleaegkgkkTVNFRLRD  465
            +   +G++V+   AA+TE G+ + S+ +DGL   +A+  +   LEAEG G+  V +RLRD
Sbjct  362  L---EGGNVE--EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  466  WGVSRQRYWGAPIPMVTTEDGQVHPVPIDQLPVILP--EDVVMDGVT-SPIKADKEWAKT  522
            W  SRQRYWG PIP++  EDG   +VP  +LP++LP   D+   G   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  523  TF-NGEPALRETDTFDTFMESSWYYARYCSPQADDIL-DPAKANYWLPVDQYIGGIEHAC  580
            T  +G  + RET+T      SSWYY RY  P+  + L D    + WLPVD Y+GG EHA 
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  581  MHLLYSRFFHKLLRDAGYVTSDEPFKQLLCQGMVLADAFYHTNEKGTKEWVAPTDVKVER  640
            +HLLY+RF HK+L D G V + EPF++L+ QGM+L+ ++   + +G+   + +TD KVE+
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY--RDSRGA---LVATD-KVEK  590

Query  641  DGKGRITQAVDNQGRNVEHSGMIKMSKSKNNGIDPQEMVDKYGADTVRLFMMFASPADMT  700
             + G + +   + G ++E++   KMSKS +N ++P+++V++YGADT+R++ MF +P D +
Sbjct  591  RD-GSFFHV--ETGEELEQAP-AKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  701  LEWQESGVEGANRFLKRVWKLVAEHSAKGVAEAVDSASLTGEQKALRRDVHKTIAKVTDD  760
            + W E G+EG+ +FL RV +L+   ++K ++E   +        AL +  + T+  VT++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLI---TTKEITEENSG--------ALDKVYNETVKAVTEQ  695

Query  761  IARRQTFNTAIAAIMELMNKLTKASQESVQDRAILDEALKAVVSMLYPITPHISFELWNA  820
            + + + FNTAIA +M ++N   K  +       ++ +  K+ V ++ P++PH++ ELW+A
Sbjct  696  VDQMK-FNTAIAQLMVFVNAANKEDK-------LFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  821  LGESD--VDNTVWPTYDESALVEDEKLIVLQVNGKLRGKLTVAADASKDQVEALGLADEN  878
            L  S+  +    WP+YDES LVE++  IV+Q++GK+++KL VA D S+++++ ++LA+E+
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  879  VMKFTDGLTVRKVIYVPGKLLNIVAN  904
            V     G  + KVI VP KL+NIV +
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVIK  833

1240) leuS in NC_013716


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  538 bits (2030),  Expect = 6e-154, Method: Compositional matrix adjust.
 Identities = 360/866 (42%), Positives = 550/866 (64%), Gaps = 48/866 (5%)

Query  5    YRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIA  63
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKTMQRNWIGRSEGVEITFDVTGYDNT  242
            V RK + QW +KITAYA+ LL+DL+ +D WP+++K MQRNWIG+S G ++TF V + D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGATYLAVAAGHPLAQKAAANNPELAAFIDECRNTKVAEADMA----TM  298
            +TV+TTRPDT+ GATY  +A+ H+L +  A   ++ A  + + +      +D+A    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVD--AITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  299  EKKGVDTGFKAVHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFATKYGLTIKP  358
            EK GV TG  A++P+ G E+PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L I P
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VILAADGSEPDLSEQALTEKGVLFNSGEFDGLAFEEAFNAIADKLAAKGVGERKVNYRLR  418
            V+        ++ E A+TE G+ +NS+ +DGL    A+  + + L A GVG+ +V YRLR
Sbjct  361  VL-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  419  DWGVSRQRYWGAPIPMVTLEDGTVQPTPEDQLPVILP--EDVVMDGIT-SPIKADPEWAK  475
            DW  SRQRYWG PIP++  EDGT  + PE +LP++LP   D+   G   SP+    +W  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  476  TT-VNGQPALRETDTFDTFMESSWYYARYTCPQYQEGMLDAKAANYWLPVDIYIGGIEHA  534
             T  +G  + RET+T      SSWYY RY  P+  E + D    + WLPVDIY+GG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  535  IMHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPKEAIVE  594
            ++HLLY RF HK++ D G+V + EP ++L+ QGM+L+ ++      + R  + + + +  
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEK  590

Query  595  RDEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQEMVERYGADTVRLFMMFASPADM  654
            RD  G +      +G+EL   + +KMSKS +N ++P+++VE+YGADT+R++ MF +P D 
Sbjct  591  RD--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  655  TLEWQESGVEGANRFLKRVWKLVYEHTSRGDVAPLNVDALSEDQKALRRDVHKTIAKVTD  714
            ++ W E G+EG+ +FL RV +L+   T++        +   E+  AL +  + T+  VT+
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLI---TTK--------EITEENSGALDKVYNETVKAVTE  694

Query  715  DIGRRQTFNTAIAAIMELMNKLAKAPQEDEQDRALMQEALLAIVRMLNPFTPHICFTLWQ  774
            ++++ + FNTAIA +M ++N         +++  L  +   ++V+++ PF+PH+   LWQ
Sbjct  695  QVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  775  SLKGEGD-IDNAPWPVADDAAMVEDSTLVVVQVNGKVRGKITVPVDASEEQVRERAGQEH  833
            +L + G+ I   PWP  D++ +VE+   +VVQ++GKV++K+ V+ D S E+++E A  ++
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  834  LVAKYLEGMTVRKVIYVPGKLLNLVV  859
             V   + G  + KVI VP KL+N+V+
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVI  832

1241) leuS in NC_011751


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  538 bits (2031),  Expect = 6e-154, Method: Compositional matrix adjust.
 Identities = 359/865 (42%), Positives = 556/865 (65%), Gaps = 46/865 (5%)

Query  5    YRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIA  63
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCTPEYYRWEQKFFTELYKKDLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W Q +FT LY K+L Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKTMQRNWIGRSEGVEITFNVNDYDNT  242
            V RK + QW +KITAYA+ LL+DL+ +D WP+++K MQRNWIG+S G ++TF+V+D D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGCTYLAVAAGHPLAQ--KAAENNPELAAFIDECR-NTKVAEAEMATME  299
            +TV+TTRPDT+ G TY  +A+ H+L +   ++++   +A +  +   ++ +A +++A  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGVDTGFKAVHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPV  359
            K GV TG  A++P+ G E+PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L+I PV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  360  ILAADGSEPDLSQQALTEKGVLFNSGEFNGLDHEAAFNAIADKLTAMGVGERKVNYRLRD  419
            +        ++ + A+TE G+ +NS+ ++GLD  +A+  + + L A GVG+ +V YRLRD
Sbjct  362  L-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMVTLEDGTVMPTPDDQLPVILP--EDVVMDGIT-SPIKADPEWAKT  476
            W  SRQRYWG PIP++  EDGT  + P+ +LP++LP   D+   G   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  T-VNGMPALRETDTFDTFMESSWYYARYTCPEYKEGMLDSKAANYWLPVDIYIGGIEHAI  535
            T  +G+ + RET+T      SSWYY RY  P+  E + D    + WLPVDIY+GG EHA+
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVER  595
            +HLLY RF HK++ D G+V + EP ++L+ QGM+L+ ++      + R  + + D +  R
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEKR  591

Query  596  DEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMT  655
            D  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D +
Sbjct  592  D--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  656  LEWQESGVEGANRFLKRVWKLVYEHTAKGDVAALNVDALTEDQKALRRDVHKTIAKVTDD  715
            + W E G+EG+ +FL RV +L+   T+K        +   E+  AL +  + T+  VT++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLI---TTK--------EITEENSGALDKVYNETVKAVTEQ  695

Query  716  IGRRQTFNTAIAAIMELMNKLAKAPTDGEQDRALMQEALLAVVRMLNPFTPHICFTLWQE  775
            +++ + FNTAIA +M ++N        ++++  L  +   + V+++ PF+PH+   LWQ 
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  776  LKGEGD-IDNAPWPVADEKAMVEDSTLVVVQVNGKVRAKITVPVDATEEQVRERAGQEHL  834
            L + G+ I   PWP  DE  +VE+   +VVQ++GKV+AK+ V+ D + E+++E A  ++ 
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  835  VAKYLDGVTVRKVIYVPGKLLNLVV  859
            V   + G  + KVI VP KL+N+V+
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVI  832

1242) PARA_02330 in NC_015964


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  538 bits (2030),  Expect = 6e-154, Method: Compositional matrix adjust.
 Identities = 361/866 (42%), Positives = 561/866 (65%), Gaps = 46/866 (5%)

Query  5    YRPDLIEPSVQQYWAENKVFKAIKDTSKEKYYCLSMFPYPSGR-LHMGHVRNYTIGDVVS  63
            Y    IEP  Q +WA+N  FK+  D+SK K+Y L MFPYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMNGKNVLQPIGWDAFGLPAEGAAIKNKTAPAKWTYENIEYMKNQLKMLGFGYDWDR  123
            R++R +G NVL+P+GWDAFGLPAE  A+     PA  T ENI   K Q++ LGF+YDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EIATCSPEYYKWEQWFFTELYKKGLVYKKTSTVNWCPNDETVLANEQV-HEGCCWRCDTP  182
            E+ T  P+YYKW QW+FT LY KGL Y     VNW  +  T +ANE+V  +G   R + P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VEQKEIPQWFIKITDYAEQLLGGLDQLPQWPDMVKTMQRNWIGRSEGVEITFDVADTAEK  242
            V +K + QW +KIT YAE+LL +L+++ +WP+ +K MQRNWIG+S G ++TF V DT   
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  VSVYTTRPDTFYGVSY--LGIaaahplaelaaeKNPQLAEFIREAK-NAKVAEADLATME  299
             +V+TTRPDT++G +Y  L+   A   A  ++++   +A++ R+A  ++ +A +DLA  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGMATGLFAIHPLTGEKLPIWVANFVLMHYGTGAVMAVPAHDQRDFEFAQKYNLPIKQV  359
            K G+ TG +AI+P+ G  +P+W+A++VL  YGTGA+MAVPAHD+RD EFA+++NL   ++
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNL---DI  358

Query  360  IAPLADEEIDLTKQAFVEHGKLVNSAEFDGLDFDSAFNGIANKLEKLGVGKRQVNYRLRD  419
            I+ L + +++    AF E+G  +NS  +DGLD  SA+  + + LE  GVG+ +V YRLRD
Sbjct  359  IPVLEGGNVE--EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMLTLPNGETVPAPIEDLPIILP--EDVVMDGV-KSPIKADPNWAKT  476
            W  SRQRYWG PIP++   +G + + P  +LP++LP   D+   G   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  TF-NGEPALKETDTFDTFMESSWYYARYTSPSYAEGMLDKDEANYWLPVDQYIGGIEHAT  535
            T  +G  + +ET+T      SSWYY RY  P  +E + D +  + WLPVD Y+GG EHA 
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLLYFRFFHKLLRDAGFVTSDEPAQKLLCQGMVLADAFYYTSPTNERIWVSPTQVTLER  595
            +HLLY RF HK+L D G V + EP QKL+ QGM+L+ ++      + R     + V+ ++
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSR----GALVATDK  587

Query  596  DEKGRIIKATDPEGRELVHTGMTKMSKSKNNGIDPQEMVEKYGADTVRLFMMFASPAEMT  655
             EK R     + E  E ++ + +KMSKS +N ++P+++VE+YGADT+R++ MF +P + +
Sbjct  588  VEK-RDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  656  LEWQESGVEGAKRFLGRVWNLVYEYSQNPAKTALDVTALSADQKALRRDVHKTIAKVSDD  715
            + W E G+EG+++FL+RV  L+         T+ ++T    +  AL +  + T+  V+++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLI---------TTKEITE--ENSGALDKVYNETVKAVTEQ  695

Query  716  IGRRQTFNTAIAAVMELMNKLTRAPLDSEQDRAVMAEALSAVVRMLYPITPHICFELWKA  775
            +++ + FNTAIA +M ++N        ++++  + ++   + V+++ P++PH+  ELW+A
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  776  L-GNENNIDHAEWVKADEAAMVEDEKLIVVQVNGKVRGKVTVAADADEETVKMVAFADEN  834
            L ++ ++I    W   DE+ +VE++  IVVQ++GKV++K+ VA D   E ++ VA+A+E+
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  835  VKKFTDNTQIVKVIYVPGKLLNVVVK  860
            V+      +I+KVI VP KL+N+V+K
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVIK  833

1243) Mmwyl1_2915 in NC_009654


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  538 bits (2030),  Expect = 6e-154, Method: Compositional matrix adjust.
 Identities = 360/861 (42%), Positives = 537/861 (63%), Gaps = 81/861 (9%)

Query  5    YNPQQIEQAAQSFWDENKVFKAIADSSKEKFYCLSMFPYPSGR-LHMGHVRNYTIGDVIS  63
            Y+   IE   Q+FW +N  FK+ +D+SK KFY L MFPYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMQGKNVLQPMGWDAFGLPAENAAIKHKTAPAKWTTENIAYMKGQLKELGFGYDWDR  123
            R++R QG NVL+PMGWDAFGLPAE+ A+     PA  T+ENIA  K Q++ LGF+YDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EIATCTPEYYKWEQWFFTQLVEKGLAYKKTAAVNWCPEDQTVLANEQV-EDGCCWRCGTN  182
            E+ T  P+YYKW QW+FT+L EKGLAY    +VNW  E  T +ANE+V  DG   R G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VEKKEISQWFIRITDYAEELLNDLDQLDGWPEKVKAMQRNWIGRSEGLEFSFAVEGKDER  242
            V +K + QW ++IT YAE LL+DL+++D WPE +K MQRNWIG+S G + +F V + D  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LSVYTTRPDTIMGVTYVAVATQHPLSLEASANNADLAAFIEESKKMSTTEADMATV----  298
            ++V+TTRPDT+ G TY  +A +H+L    +   +D A  + + K+ ++  +D+A      
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALV--DAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  299  EKKGMDTGFKAIHPITGEAVPVYAANFVLMDYGSGAVMSVPAHDQRDFEFAKKYNLAIKQ  358
            EK G+ TG  AI+P+ G  +PV  A++VL  YG+GA+M+VPAHD+RD EFAK++NL I  
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VVQPAGDEVIDLEKAAFTEKGVLCNSGEFDGLAFKEAFDAIAAWMVERNLGEVKVNYRLR  418
            V++ +     ++E AAFTE G+  NS+ +DGL    A+  +  W+    +G+ +V YRLR
Sbjct  361  VLEGG-----NVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  419  DWGVSRQRYWGTPIPTINLKDGSVVPVPQDQLPVELPT--DVIMDGV-NSPIKNNPDFSS  475
            DW  SRQRYWG PIP I+  DG+  +VP+ +LP+ LP   D+   G  +SP+ N  D   
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  476  IMF-NGEEAERETDTFDTFMESSWYFARYCCPDSTDAMLTEE-ANYWLPVDQYVGGVEHA  533
            +   +G  + RET+T      SSWY+ RY  P++T+ +  EE  + WLPVD YVGG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  534  ILHLLYSRFFHKLLRDAGLVNSDEPFKRLLTQGMV-------------------NKDGT-  573
            +LHLLY+RF HK+L D G+V + EPF++L+ QGM+                   ++DG+ 
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSF  595

Query  574  --------------KMSKSKGNTVDPQEMIEKYGADTVRLFMMFSAPPEQSLEWNDAGVD  619
                          KMSKS  N V+P++++E+YGADT+R++ MF +P + S+ W++ G++
Sbjct  596  FHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLE  655

Query  620  GASRFLRRLWALSYRHTNAGKVGELNIAELNGAQKALRRKTHETIQKVSDDIERRQTFNT  679
            G+ +FL R+    YR   +  + E N + L+       +  +ET++ V++++++ + FNT
Sbjct  656  GSRKFLDRV----YRLITTKEITEENSGALD-------KVYNETVKAVTEQVDQMK-FNT  703

Query  680  AIAAVMELCNEISK----FEDSSelglaveqealeaatlllSPIVPHIAHQLWSEL-GHS  734
            AIA +M + N  +K    F D +            +   L++P+ PH++++LW  L + +
Sbjct  704  AIAQLMVFVNAANKEDKLFSDYA-----------KGFVQLIAPFAPHLGEELWQALTASG  752

Query  735  DNIVNTPWPTLDEEALIKDELTIVVQVLGKKRAELTVSANADNKTIEAEALAHPSVAKLL  794
            ++I   PWP+ DE  L+ +++ IVVQ+ GK +A L V+ +     ++  ALA+  V   +
Sbjct  753  ESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEI  812

Query  795  EGKTVRKVIVVPGRLVNIVAN  815
             GK + KVI VP +LVNIV +
Sbjct  813  AGKDIIKVIAVPNKLVNIVIK  833

1244) leuS in NC_008536


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  538 bits (2030),  Expect = 6e-154, Method: Compositional matrix adjust.
 Identities = 342/848 (41%), Positives = 543/848 (65%), Gaps = 61/848 (7%)

Query  6    YDHIAIELKWHERWQDAQFYKAEENSAKPKFYVLEMLPYPSGT-LHIGHIRNYSIGDALA  64
            YDH AIE KW+  W D + +K+  +++KPKFY L+M+PYPSG+ LH+GH   Y+  D L+
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  65   RYKWMRGFNVLHPMGWDAFGLPAENAAIANKVPPRQWTLQNIAAMKKTHRRFAFSYDWDR  124
            R+K+ +G NVLHPMGWDAFGLPAE+ A+     P + T +NIA  K+    ++FSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  125  EVSTCEPEYYRWNQWFFLRMLERGLAYRKRALVNWCPKCATVLANEQVVDGCCWRHEGTP  184
            EV+T +P+YY+W QW+F ++ E+GLAY     VNW    +T +ANE+V+ +    + G P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  185  VEQRALDQWFLKITDYADQLLDEMARLEGGWPERVLTMQRNWIGRSEGAEIDFTLAGAGT  244
            V ++++ QW LKIT YA++LL+++  ++  WPE +  MQRNWIG+S GA++ F + +++ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD--WPESIKDMQRNWIGKSTGANVTFKVKDTDK  241

Query  245  PIRVFTTRVDTIYGATSVILAPEHPLNETLLDSEKKA-----KAKAMVDSRAGRDPGDID  299
             + VFTTR DT++GAT  +LAPEH+L +++  S++       K +A + S  +R     +
Sbjct  242  DFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKE  301

Query  300  KEGFFTGHYAVNPYNGEQVPIWIANFVLMGYGTGAIMAVPAHDERDFEFCTKYGIPITPV  359
            K G  TG YA+NP NG ++P+WIA++VL +YGTGAIMAVPAHDERD EF  ++ + I PV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  360  IRPVDQPAGEPVALPYGEYGILENSGEWSGLASAEARRQMSAYAEQHGFGKSAITFRIKD  419
            +      +G+    ++ E G+  NS+   GL  A A  +M    E +G G+  +T+R++D
Sbjct  362  L-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGISRQRYWGTPIPVIH--CPSCGvvpvpddqlpvvlpdRIEITGAGRSPLENVPEFVNV  477
            W +SRQRYWG PIP+IH    +   VP ++  L + +   I  +G+G SPL NV + ++V
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  478  ACPKCGEPARRETDTMDTFVDSSWYFYRYCDPHNSERPFDPAKIAYWFEIDQYIGGIEHA  537
            +    G  +RRET+TM    +SSWY+ RY DPHN+E+  D   +  W+ +D Y+GG EHA
Sbjct  477  TRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  538  ILHLIYSRFFTKVMRDIGLISNNEPARRLFTQGMVIAEG---------------------  576
            +LHL+Y+RF  KV+ D+G+++ +EP ++LF QGM+++ +                     
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSF  595

Query  577  -------------AKMSKSKGNVVGADLLADKFGADTARMFVLSNVPPEKEVDWREEGAE  623
                         AKMSKS  NVV +D + +++GADT R++ +   P +  + W EEG E
Sbjct  596  FHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLE  655

Query  624  GTYRFLGRVYRFTTRNVPAQQRSGDADRKVVRKLHQTLKKITEDFETRWHFNTCIASIME  683
            G+ +FL+RVYR+ T +  +++ SG  D    +  ++T+K +TE+ +    FNT IA +M 
Sbjct  656  GSRKFLDRVYRLITTKEITEENSGALD----KVYNETVKAVTEQVDQM-KFNTAIAQLM-  709

Query  684  LVNLLYAEEQNISAAVMPQILESLALMLAPFAPYLSQEMWEEIGKEGPVFR-QAWPAFDP  742
                ++ +  N    + ++   ++  ++APFAP L++E+W+ +   G  +   +WP++D 
Sbjct  710  ----VFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDE  765

Query  743  ELAKEEGAEIVVQVNGKVRTRITAPFGTAKEELESRSLAHEKVKPFIDGKQVMKIITVPD  802
                E++ EIVVQ++GKV++++  + + ++EEL+  +LA+EKV++ I GK+++K+I+VP+
Sbjct  766  SKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPN  825

Query  803  KLVNIVVK  810
            KLVNIV+K
Sbjct  826  KLVNIVIK  833

1245) leuS in NC_007645


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  538 bits (2030),  Expect = 6e-154, Method: Compositional matrix adjust.
 Identities = 345/847 (41%), Positives = 543/847 (65%), Gaps = 53/847 (6%)

Query  4    LYHPKKVEQEAQKFWEETDAFKVDEEPGKEKFYCLSMFPYPSGK-LHMGHVRNYTIGDVI  62
            +Y+   +E   Q FW + ++FK + +++K KFY L MFPYPSG  LH+GH   YT  D++
Sbjct  3    FYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDIL  62

Query  63   SRYQRMQGKNVLQPMGWDAFGLPAENAALKNNVAPAKWTYENIAYMKNQLKLLGFGYDWN  122
            SR++R QG NVL+PMGWDAFGLPAE+ A+     PA  T ENIA  K Q++ LGF+YDW+
Sbjct  63   SRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWD  122

Query  123  RELATCRPEYYKWEQWFFTRLYEKGLVYKKMSTVNWDPVDETVLANEQVI-DGKGWRSGA  181
            RE+ T  P+YYKW QW+FT+LYEKGL Y     VNW     T +ANE+V+ DG + R+G 
Sbjct  123  REVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGY  182

Query  182  VVERREIPQWFIKITDYAEQLLNDLDKLENWPEQVKTMQRNWINKSEGVEFHFKLKDHDG  241
             V R+ + QW +KIT YAE+LL+DL+ ++ WPE +K MQRNWI KS G +  FK+KD D 
Sbjct  183  PVVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDK  241

Query  242  DLQVYTTRPDTIMGVTYVAIAPQHPLALEAAASNPQLAKFLDECKNTKVAEADMA----T  297
            D+ V+TTRPDT+ G TY  +AP+H+L    A + ++ A  + + K      +D+A    +
Sbjct  242  DFTVFTTRPDTLFGATYAVLAPEHALV--DAITTSDQAEAVADYKRQASLKSDLARTDLA  299

Query  298  MEKRGMDTGFFVIHPLTNEPAPIWVANFVLMDYGSGAVMSVPGHDERDHEFALKYGLPIK  357
             EK G+ TG + I+P+     P+W+A++VL  YG+GA+M+VP+HDERD EFA ++ L   
Sbjct  300  KEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNL---  356

Query  358  QVISVIDADEVDIQEKAITEKGILVNSGEFTGMTSQEAFDAVAEKLTAMGIGEKKINYRL  417
            ++I+V+++++V+  E A+TE G+ +NS+ + G+    A+  + E L A G+G+ ++ YRL
Sbjct  357  DIIPVLEGGNVE--EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRL  414

Query  418  RDWGVSRQRYWGAPIPMMTQEDGTEVPVPLADLPVRLPEDVEM---DGVKSPIKADPNW-  473
            RDW  SRQRYWG PIP++  EDGT  +VP ++LP+ LP   ++   +   SP+    +W 
Sbjct  415  RDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWL  474

Query  474  -SKRSYNGQPATQETDTFDTFMESSWYYARFCCPNLESAMLDPAAANYWLPVDYYVGGIE  532
               R  +G  + +ET+T      SSWYY R+  P+    + D    + WLPVD YVGG E
Sbjct  475  EVTRE-DGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAE  533

Query  533  HAILHLLYSRFFHKLLRDEGLVDSDEPFKKLLCQGMVIAETFYREDPSSKKTYFNPRDVR  592
            HA+LHLLY+RF HK+L D G+V + EPF+KL+ QGM+++ + YR+          +R+  
Sbjct  534  HAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS-YRD----------SRGAL  582

Query  593  VELDTQGNSPKAFL-IEDGQPVIIGPKEKMSKSKNNGVDPQELIDKYGADTVRLFTMFAA  651
            V  D   +   +F+ +E G+ +  +P  KMSKS +N V+P++++++YGADT+R++ MF +
Sbjct  583  VATDKVEKRDGSFFHVETGEELEQAP-AKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMG  641

Query  652  PPEQSLEWSESGVEGQHRFLRRLWKLVHTHVEKKGAAPLNVAELNETQRTLRRKTHETIK  711
            P + S+ WSE G+EG ++FL R+ +L+ T          +++E  E   +L +  +ET+K
Sbjct  642  PLDASIAWSEEGLEGSRKFLDRVYRLITTK---------EITE--ENSGALDKVYNETVK  690

Query  712  KMTDEFNHRMAINTGIAMVMELLNELSRFEDDSPQGLAVVQEALETAVLVLAPIVPHISH  771
             +T++ ++ M +NT+IA +M        F + + +   +  +     V ++AP+ PH+++
Sbjct  691  AVTEQVDQ-MKFNTAIAQLMV-------FVNAANKEDKLFSDYAKGFVQLIAPFAPHLGE  742

Query  772  GLWREL-GHEDVVMNAPWPQLDEKALEKDSIELVVQVNGKLRARIQAAASANKDELEKLA  830
             LW+ L +  + +   PWP  DE  L  + +E+VVQ++GK++A++  A   +++EL+ +A
Sbjct  743  ELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVA  802

Query  831  FDDENVQ  837
            + +E+VQ
Sbjct  803  LANEKVQ  809

1246) leuS in NC_017308


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  538 bits (2030),  Expect = 7e-154, Method: Compositional matrix adjust.
 Identities = 352/742 (48%), Positives = 510/742 (69%), Gaps = 68/742 (9%)

Query  224  LVYRSHSMVNWCPGLGTVLANEEVTADGRSERGNFPVFRRNLSQWMMRITAYSDRLIDDL  283
            L Y ++  VNW   LGT +ANEEV +DG SERG +PV R+ + QWM++ITAY++RL++DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  284  DALDWPDKVKSMQRNWIGRSRGAEVDFDV--LGHTITVFTTRPDTLFGASYMVLAPEHEL  341
            + +DWP+ +K MQRNWIG+S GA+V F V   +  +TVFTTRPDTLFGA+Y VLAPEH L
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  342  VDALVAAGTNSYDGVDPRWTFEQSCPADAVKAYRASIAAKSDLERQE-NKEKTGVYLGVN  400
            VDA+ +++                  A+AV  Y+   + KSDL R +  KEKTGV  G  
Sbjct  268  VDAITTSD-----------------QAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSY  310

Query  401  AVNPVNGESIPVFIGDYVLTGYGTGAIMAVPAHDTRDYEFATEFGLPIREVVAGGNVAEE  460
            A+NPVNG  +PV I+DYVL++YGTGAIMAVPAHD RD EFA +F L I  V+ GGNV E 
Sbjct  311  AINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEA  370

Query  461  AYTESGVAVNSANDEGLDINGLDKQEAIARVIEWLVDKQKGSEKIQYKLRDWLFARQRYW  520
            A+TE G+ +NS       ++GLDK  AIA+++EWL     G+E++ Y+LRDWLF+RQRYW
Sbjct  371  AFTEDGLHINSDF-----LDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYW  425

Query  521  GEPFPVVYDADGVAHALPESMLPVELPEVEDYKPVSFDPDDADSEPQPPLAKATEWTQVE  580
            GEP+P++   DG + A+PES LP+ LP   D +P         +  ++PLA+ T+W +V 
Sbjct  426  GEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTDWLEVT  477

Query  581  LDLGDGLKTYTRDTNVMPQWAGSSWYQLRYIDPTNNKQFCDIENERYWTGPRGENdlggv  640
             +  DG+K   R+TN MPQWAGSSWY LRYIDP N  ++ D E  + W           V
Sbjct  478  RE--DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLP---------V  525

Query  641  dlyvggvEHAVLHLLYSRFWHKVLFDLGYVTSGEPYRRLFNQGYIQAFAYTDSRGVYVPA  700
            D+YVGG EHAVLHLLY+RFWHKVL+DLG V + EP+++LFNQG I + +Y DSRG  V++
Sbjct  526  DIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVAT  585

Query  701  AEVEEKDGKFFY--QGEEVNQEYGKMGKSLKNAVAPDEICSDFGADTLRVYEMAMGPLDT  758
              VE +DG FF    GEE++Q  +KM+KSLKN V PD++  ++GADTLRVYEM MGPLD+
Sbjct  586  DKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  759  SRPWATKDVIGAHRFLQRLWRLVVSEDDGSVVVTDAGLADDDLKQLHRTIAGMRDDYEGL  818
            S +W+  ++ G+++FL+R+ RL+ + +   +   ++G  D   K  + T+ ++ ++ + +
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLITTKE---ITEENSGALD---KVYNETVKAVTEQVDQM  699

Query  819  RINTVVAKAIEYVNYLTK------NYAKGAPRAAVEPLVIMVAPVAPHIAEELWKRL-GH  871
            ++NT +A+ + +VN   K      +YAKG        +V ++AP APH++EELW+ L + 
Sbjct  700  KFNTAIAQLMVFVNAANKEDKLFSDYAKG--------FVQLIAPFAPHLGEELWQALTAS  751

Query  872  EETITFVAFPDYDEKWLVDDEVEMPIQINGKVRARIMVPADATQDQIVEIALAEPTVQSH  931
             E+I++V+ P YDE  LV+++VE+ +QI+GKV+A+++V+ D +++++ E+ALA+  VQ++
Sbjct  752  GESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAE  811

Query  932  LEGKNLFKQIVVPGRMVNLVIK  953
            + GK+++K I VP ++VN+VIK
Sbjct  812  IAGKDIIKVIAVPNKLVNIVIK  833


 Score =  141 bits (520),  Expect = 2e-34, Method: Compositional matrix adjust.
 Identities = 81/149 (55%), Positives = 106/149 (72%), Gaps = 10/149 (6%)

Query  21   GDIERTWQQFWIDNGTFNAPNPVGDLAVAGQELPEDKLFVQDMFPYPSGAGLHVGHPLGY  80
              IE  WQ FW DN TF++          G + +  K++  DMFPYPSGAGLHVGHP GY
Sbjct  7    TAIEPKWQAFWADNHTFKT----------GTDASKPKFYALDMFPYPSGAGLHVGHPEGY  56

Query  81   IATDVFARFNRMLGKNVLHTLGYDAFGLPAEQYAIQTGTHPRATTMSNIANMQRQLSALG  140
             ATD+++RF+R  G NVLH +G DAFGLPAEQYA++TG +P   T  NIAN +RQ++ALG
Sbjct  57   TATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALG  116

Query  141  LGHDPRRSVATTDPEFYKWTQWIFLQIFN  169
            ++ D  R V TTDP++YKWTQWIF ++++
Sbjct  117  FSYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1247) leuS in NC_016932


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  538 bits (2030),  Expect = 7e-154, Method: Compositional matrix adjust.
 Identities = 352/742 (48%), Positives = 510/742 (69%), Gaps = 68/742 (9%)

Query  224  LVYRSHSMVNWCPGLGTVLANEEVTADGRSERGNFPVFRRNLSQWMMRITAYSDRLIDDL  283
            L Y ++  VNW   LGT +ANEEV +DG SERG +PV R+ + QWM++ITAY++RL++DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  284  DALDWPDKVKSMQRNWIGRSRGAEVDFDV--LGHTITVFTTRPDTLFGASYMVLAPEHEL  341
            + +DWP+ +K MQRNWIG+S GA+V F V   +  +TVFTTRPDTLFGA+Y VLAPEH L
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  342  VDALVAAGTNSYDGVDPRWTFEQSCPADAVKAYRASIAAKSDLERQE-NKEKTGVYLGVN  400
            VDA+ +++                  A+AV  Y+   + KSDL R +  KEKTGV  G  
Sbjct  268  VDAITTSD-----------------QAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSY  310

Query  401  AVNPVNGESIPVFIGDYVLTGYGTGAIMAVPAHDTRDYEFATEFGLPIREVVAGGNVAEE  460
            A+NPVNG  +PV I+DYVL++YGTGAIMAVPAHD RD EFA +F L I  V+ GGNV E 
Sbjct  311  AINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEA  370

Query  461  AYTESGVAVNSANDEGLDINGLDKQEAIARVIEWLVDKQKGSEKIQYKLRDWLFARQRYW  520
            A+TE G+ +NS       ++GLDK  AIA+++EWL     G+E++ Y+LRDWLF+RQRYW
Sbjct  371  AFTEDGLHINSDF-----LDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYW  425

Query  521  GEPFPVVYDADGVAHALPESMLPVELPEVEDYKPVSFDPDDADSEPQPPLAKATEWTQVE  580
            GEP+P++   DG + A+PES LP+ LP   D +P         +  ++PLA+ T+W +V 
Sbjct  426  GEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTDWLEVT  477

Query  581  LDLGDGLKTYTRDTNVMPQWAGSSWYQLRYIDPTNNKQFCDIENERYWTGPRGENdlggv  640
             +  DG+K   R+TN MPQWAGSSWY LRYIDP N  ++ D E  + W           V
Sbjct  478  RE--DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLP---------V  525

Query  641  dlyvggvEHAVLHLLYSRFWHKVLFDLGYVTSGEPYRRLFNQGYIQAFAYTDSRGVYVPA  700
            D+YVGG EHAVLHLLY+RFWHKVL+DLG V + EP+++LFNQG I + +Y DSRG  V++
Sbjct  526  DIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVAT  585

Query  701  AEVEEKDGKFFY--QGEEVNQEYGKMGKSLKNAVAPDEICSDFGADTLRVYEMAMGPLDT  758
              VE +DG FF    GEE++Q  +KM+KSLKN V PD++  ++GADTLRVYEM MGPLD+
Sbjct  586  DKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  759  SRPWATKDVIGAHRFLQRLWRLVVSEDDGSVVVTDAGLADDDLKQLHRTIAGMRDDYEGL  818
            S +W+  ++ G+++FL+R+ RL+ + +   +   ++G  D   K  + T+ ++ ++ + +
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLITTKE---ITEENSGALD---KVYNETVKAVTEQVDQM  699

Query  819  RINTVVAKAIEYVNYLTK------NYAKGAPRAAVEPLVIMVAPVAPHIAEELWKRL-GH  871
            ++NT +A+ + +VN   K      +YAKG        +V ++AP APH++EELW+ L + 
Sbjct  700  KFNTAIAQLMVFVNAANKEDKLFSDYAKG--------FVQLIAPFAPHLGEELWQALTAS  751

Query  872  EETITFVAFPDYDEKWLVDDEVEMPIQINGKVRARIMVPADATQDQIVEIALAEPTVQSH  931
             E+I++V+ P YDE  LV+++VE+ +QI+GKV+A+++V+ D +++++ E+ALA+  VQ++
Sbjct  752  GESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAE  811

Query  932  LEGKNLFKQIVVPGRMVNLVIK  953
            + GK+++K I VP ++VN+VIK
Sbjct  812  IAGKDIIKVIAVPNKLVNIVIK  833


 Score =  141 bits (520),  Expect = 2e-34, Method: Compositional matrix adjust.
 Identities = 81/149 (55%), Positives = 106/149 (72%), Gaps = 10/149 (6%)

Query  21   GDIERTWQQFWIDNGTFNAPNPVGDLAVAGQELPEDKLFVQDMFPYPSGAGLHVGHPLGY  80
              IE  WQ FW DN TF++          G + +  K++  DMFPYPSGAGLHVGHP GY
Sbjct  7    TAIEPKWQAFWADNHTFKT----------GTDASKPKFYALDMFPYPSGAGLHVGHPEGY  56

Query  81   IATDVFARFNRMLGKNVLHTLGYDAFGLPAEQYAIQTGTHPRATTMSNIANMQRQLSALG  140
             ATD+++RF+R  G NVLH +G DAFGLPAEQYA++TG +P   T  NIAN +RQ++ALG
Sbjct  57   TATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALG  116

Query  141  LGHDPRRSVATTDPEFYKWTQWIFLQIFN  169
            ++ D  R V TTDP++YKWTQWIF ++++
Sbjct  117  FSYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1248) leuS in NC_017307


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  538 bits (2030),  Expect = 7e-154, Method: Compositional matrix adjust.
 Identities = 352/742 (48%), Positives = 510/742 (69%), Gaps = 68/742 (9%)

Query  224  LVYRSHSMVNWCPGLGTVLANEEVTADGRSERGNFPVFRRNLSQWMMRITAYSDRLIDDL  283
            L Y ++  VNW   LGT +ANEEV +DG SERG +PV R+ + QWM++ITAY++RL++DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  284  DALDWPDKVKSMQRNWIGRSRGAEVDFDV--LGHTITVFTTRPDTLFGASYMVLAPEHEL  341
            + +DWP+ +K MQRNWIG+S GA+V F V   +  +TVFTTRPDTLFGA+Y VLAPEH L
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  342  VDALVAAGTNSYDGVDPRWTFEQSCPADAVKAYRASIAAKSDLERQE-NKEKTGVYLGVN  400
            VDA+ +++                  A+AV  Y+   + KSDL R +  KEKTGV  G  
Sbjct  268  VDAITTSD-----------------QAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSY  310

Query  401  AVNPVNGESIPVFIGDYVLTGYGTGAIMAVPAHDTRDYEFATEFGLPIREVVAGGNVAEE  460
            A+NPVNG  +PV I+DYVL++YGTGAIMAVPAHD RD EFA +F L I  V+ GGNV E 
Sbjct  311  AINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEA  370

Query  461  AYTESGVAVNSANDEGLDINGLDKQEAIARVIEWLVDKQKGSEKIQYKLRDWLFARQRYW  520
            A+TE G+ +NS       ++GLDK  AIA+++EWL     G+E++ Y+LRDWLF+RQRYW
Sbjct  371  AFTEDGLHINSDF-----LDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYW  425

Query  521  GEPFPVVYDADGVAHALPESMLPVELPEVEDYKPVSFDPDDADSEPQPPLAKATEWTQVE  580
            GEP+P++   DG + A+PES LP+ LP   D +P         +  ++PLA+ T+W +V 
Sbjct  426  GEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTDWLEVT  477

Query  581  LDLGDGLKTYTRDTNVMPQWAGSSWYQLRYIDPTNNKQFCDIENERYWTGPRGENdlggv  640
             +  DG+K   R+TN MPQWAGSSWY LRYIDP N  ++ D E  + W           V
Sbjct  478  RE--DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLP---------V  525

Query  641  dlyvggvEHAVLHLLYSRFWHKVLFDLGYVTSGEPYRRLFNQGYIQAFAYTDSRGVYVPA  700
            D+YVGG EHAVLHLLY+RFWHKVL+DLG V + EP+++LFNQG I + +Y DSRG  V++
Sbjct  526  DIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVAT  585

Query  701  AEVEEKDGKFFY--QGEEVNQEYGKMGKSLKNAVAPDEICSDFGADTLRVYEMAMGPLDT  758
              VE +DG FF    GEE++Q  +KM+KSLKN V PD++  ++GADTLRVYEM MGPLD+
Sbjct  586  DKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  759  SRPWATKDVIGAHRFLQRLWRLVVSEDDGSVVVTDAGLADDDLKQLHRTIAGMRDDYEGL  818
            S +W+  ++ G+++FL+R+ RL+ + +   +   ++G  D   K  + T+ ++ ++ + +
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLITTKE---ITEENSGALD---KVYNETVKAVTEQVDQM  699

Query  819  RINTVVAKAIEYVNYLTK------NYAKGAPRAAVEPLVIMVAPVAPHIAEELWKRL-GH  871
            ++NT +A+ + +VN   K      +YAKG        +V ++AP APH++EELW+ L + 
Sbjct  700  KFNTAIAQLMVFVNAANKEDKLFSDYAKG--------FVQLIAPFAPHLGEELWQALTAS  751

Query  872  EETITFVAFPDYDEKWLVDDEVEMPIQINGKVRARIMVPADATQDQIVEIALAEPTVQSH  931
             E+I++V+ P YDE  LV+++VE+ +QI+GKV+A+++V+ D +++++ E+ALA+  VQ++
Sbjct  752  GESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAE  811

Query  932  LEGKNLFKQIVVPGRMVNLVIK  953
            + GK+++K I VP ++VN+VIK
Sbjct  812  IAGKDIIKVIAVPNKLVNIVIK  833


 Score =  141 bits (520),  Expect = 2e-34, Method: Compositional matrix adjust.
 Identities = 81/149 (55%), Positives = 106/149 (72%), Gaps = 10/149 (6%)

Query  21   GDIERTWQQFWIDNGTFNAPNPVGDLAVAGQELPEDKLFVQDMFPYPSGAGLHVGHPLGY  80
              IE  WQ FW DN TF++          G + +  K++  DMFPYPSGAGLHVGHP GY
Sbjct  7    TAIEPKWQAFWADNHTFKT----------GTDASKPKFYALDMFPYPSGAGLHVGHPEGY  56

Query  81   IATDVFARFNRMLGKNVLHTLGYDAFGLPAEQYAIQTGTHPRATTMSNIANMQRQLSALG  140
             ATD+++RF+R  G NVLH +G DAFGLPAEQYA++TG +P   T  NIAN +RQ++ALG
Sbjct  57   TATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALG  116

Query  141  LGHDPRRSVATTDPEFYKWTQWIFLQIFN  169
            ++ D  R V TTDP++YKWTQWIF ++++
Sbjct  117  FSYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1249) leuS in NC_017945


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  538 bits (2030),  Expect = 8e-154, Method: Compositional matrix adjust.
 Identities = 352/742 (48%), Positives = 510/742 (69%), Gaps = 68/742 (9%)

Query  231  LVYRSHSMVNWCPGLGTVLANEEVTADGRSERGNFPVFRRNLSQWMMRITAYSDRLIDDL  290
            L Y ++  VNW   LGT +ANEEV +DG SERG +PV R+ + QWM++ITAY++RL++DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  291  DALDWPDKVKSMQRNWIGRSRGAEVDFDV--LGHTITVFTTRPDTLFGASYMVLAPEHEL  348
            + +DWP+ +K MQRNWIG+S GA+V F V   +  +TVFTTRPDTLFGA+Y VLAPEH L
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  349  VDALVAAGTNSYDGVDPRWTFEQSCPADAVKAYRASIAAKSDLERQE-NKEKTGVYLGVN  407
            VDA+ +++                  A+AV  Y+   + KSDL R +  KEKTGV  G  
Sbjct  268  VDAITTSD-----------------QAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSY  310

Query  408  AVNPVNGESIPVFIGDYVLTGYGTGAIMAVPAHDTRDYEFATEFGLPIREVVAGGNVAEE  467
            A+NPVNG  +PV I+DYVL++YGTGAIMAVPAHD RD EFA +F L I  V+ GGNV E 
Sbjct  311  AINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEA  370

Query  468  AYTESGVAVNSANDEGLDINGLDKQEAIARVIEWLVDKQKGSEKIQYKLRDWLFARQRYW  527
            A+TE G+ +NS       ++GLDK  AIA+++EWL     G+E++ Y+LRDWLF+RQRYW
Sbjct  371  AFTEDGLHINSDF-----LDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYW  425

Query  528  GEPFPVVYDADGVAHALPESMLPVELPEVEDYKPVSFDPDDADSEPQPPLAKATEWTQVE  587
            GEP+P++   DG + A+PES LP+ LP   D +P         +  ++PLA+ T+W +V 
Sbjct  426  GEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTDWLEVT  477

Query  588  LDLGDGLKTYTRDTNVMPQWAGSSWYQLRYIDPTNNKQFCDIENERYWTGPRGENdlggv  647
             +  DG+K   R+TN MPQWAGSSWY LRYIDP N  ++ D E  + W           V
Sbjct  478  RE--DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLP---------V  525

Query  648  dlyvggvEHAVLHLLYSRFWHKVLFDLGYVTSGEPYRRLFNQGYIQAFAYTDSRGVYVPA  707
            D+YVGG EHAVLHLLY+RFWHKVL+DLG V + EP+++LFNQG I + +Y DSRG  V++
Sbjct  526  DIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVAT  585

Query  708  AEVEEKDGKFFY--QGEEVNQEYGKMGKSLKNAVAPDEICSDFGADTLRVYEMAMGPLDT  765
              VE +DG FF    GEE++Q  +KM+KSLKN V PD++  ++GADTLRVYEM MGPLD+
Sbjct  586  DKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  766  SRPWATKDVIGAHRFLQRLWRLVVSEDDGSVVVTDAGLADDDLKQLHRTIAGMRDDYEGL  825
            S +W+  ++ G+++FL+R+ RL+ + +   +   ++G  D   K  + T+ ++ ++ + +
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLITTKE---ITEENSGALD---KVYNETVKAVTEQVDQM  699

Query  826  RINTVVAKAIEYVNYLTK------NYAKGAPRAAVEPLVIMVAPVAPHIAEELWKRL-GH  878
            ++NT +A+ + +VN   K      +YAKG        +V ++AP APH++EELW+ L + 
Sbjct  700  KFNTAIAQLMVFVNAANKEDKLFSDYAKG--------FVQLIAPFAPHLGEELWQALTAS  751

Query  879  EETITFVAFPDYDEKWLVDDEVEMPIQINGKVRARIMVPADATQDQIVEIALAEPTVQSH  938
             E+I++V+ P YDE  LV+++VE+ +QI+GKV+A+++V+ D +++++ E+ALA+  VQ++
Sbjct  752  GESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAE  811

Query  939  LEGKNLFKQIVVPGRMVNLVIK  960
            + GK+++K I VP ++VN+VIK
Sbjct  812  IAGKDIIKVIAVPNKLVNIVIK  833


 Score =  141 bits (520),  Expect = 2e-34, Method: Compositional matrix adjust.
 Identities = 81/149 (55%), Positives = 106/149 (72%), Gaps = 10/149 (6%)

Query  28   GDIERTWQQFWIDNGTFNAPNPVGDLAVAGQELPEDKLFVQDMFPYPSGAGLHVGHPLGY  87
              IE  WQ FW DN TF++          G + +  K++  DMFPYPSGAGLHVGHP GY
Sbjct  7    TAIEPKWQAFWADNHTFKT----------GTDASKPKFYALDMFPYPSGAGLHVGHPEGY  56

Query  88   IATDVFARFNRMLGKNVLHTLGYDAFGLPAEQYAIQTGTHPRATTMSNIANMQRQLSALG  147
             ATD+++RF+R  G NVLH +G DAFGLPAEQYA++TG +P   T  NIAN +RQ++ALG
Sbjct  57   TATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALG  116

Query  148  LGHDPRRSVATTDPEFYKWTQWIFLQIFN  176
            ++ D  R V TTDP++YKWTQWIF ++++
Sbjct  117  FSYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1250) leuS in NC_020055


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  538 bits (2029),  Expect = 8e-154, Method: Compositional matrix adjust.
 Identities = 359/871 (42%), Positives = 542/871 (63%), Gaps = 78/871 (8%)

Query  1    MGFGKYEPELIEKKWQKEWTDTGAFNVEADESRPKYYVLEMFPYPSGK-IHMGHVRNYSI  59
            M F  Y+   IE KWQ  W+D  +F+  +D S+PK+Y L+MFPYPSG  +H+GH   Y+ 
Sbjct  1    MTF--YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTA  58

Query  60   GDVVARYKRMKGFNVLHPMGWDAFGLPAENAAIKHNTHPAEWTYANIDDMRTQLKRLGYS  119
             D+++R+KR +G NVLHPMGWDAFGLPAE+ A+    +PAE T  NI + + Q++ LG+S
Sbjct  59   TDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFS  118

Query  120  YDWRREMATCHPGYYKWEQQFFLKFLEKGLVYRKKSPVNWCETCHTVLANEQV-EEGLCW  178
            YDW RE+ T +P YYKW Q +F K+ EKGL Y    PVNW E   T +ANE+V  +G   
Sbjct  119  YDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSE  178

Query  179  RCDTQVEQKELSQWFMRITDYAeelldslsdleGGWPDRVITMQRNWIGKSIGAELNFEI  238
            R +  V +K + QW ++IT YAE LL+ L ++  +WP+ +  MQRNWIGKS GA++ F +
Sbjct  179  RGGYPVVRKPMRQWMLKITAYAERLLEDLEEV--DWPESIKDMQRNWIGKSTGANVTFKV  236

Query  239  EGCDDTISVFTTRPDTLYGATFMSLAAEHPMVEKLIADRPEAEKVREFVTKVSNMDRIVR  298
             + D  ++VFTTRPDTL+GAT+  LA+EH++V+  I+   +AE V ++  + S    + R
Sbjct  237  KDTDKDFTVFTTRPDTLFGATYAVLAPEHALVDA-ITTSDQAEAVADYKRQASLKSDLAR  295

Query  299  GADDLEKEGVFTGAYCINPLSGQKMPIYVANFVLMGYGTGAVMAVPAHDQRDYEFAKKYD  358
                 EK GV TG+Y INP++G+ MP+ +A++VL +YGTGA+MAVPAHD+RD EFAK+++
Sbjct  296  TDLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFN  355

Query  359  LPMQVVIQPEGETLNLSEMTEAYTAPGVLTNSGEFDNMSNEDAKGAIVDYLGKSGKGKKS  418
            L +  V+  EG  ++      A+T  G+  NS+ +D + +  A + +V+ L   G G+ +
Sbjct  356  LDIIPVL--EGGNVE----EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNEN  409

Query  419  VNYRLRDWNISRQRFWGSPIPVIYCDHCGIVPVPEQDLPVVLP--EDAVMNEDGRSPLPE  476
            V YRLRDW +SRQR+WG PIP+I  ++    +VPE +LP+VLP   D   +  G SPL++
Sbjct  410  VTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLAN  469

Query  477  MESFYNVVCPTCGKMAQRETDTMDTFVESSWYFMRYTDARKAGAPFNRDALEYWAPVDQY  536
            +    +V      K ++RET+TM     SSWY++RY D++++    + + L  W PVD Y
Sbjct  470  VTDWLEVTREDGVK-GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIY  528

Query  537  IGGIEHAILHLLYARFFTKLLRDEGYTSLSEPFKNLLTQGMVL-----------------  579
            +GG EHA+LHLLYARF  K+L D G  +  EPF++L+ QGM+L                 
Sbjct  529  VGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKV  588

Query  580  --KDG---------------AKMSKSKGNVVDPNSMIAKYGADATRLFILFASPPEKDLE  622
              +DG               AKMSKS  NVV+P+ ++ +YGAD+ R++ +F +P +  + 
Sbjct  589  EKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIA  648

Query  623  WSDQGLEGASRFLNRIWRLAEDLEGKIAPVGACAKPSAELPSEAKKLRRKEHETVSRASR  682
            WS++GLEG+ +FL+R+ RL                 + E+  E      K  +   +A  
Sbjct  649  WSEEGLEGSRKFLDRVYRLI---------------TTKEITEENSGALDKVYNETVKAVT  693

Query  683  DMENKFQFNTVIAASMELVNEIYSLKEKLSETEEGRFA-LSSAFSTVLTVLSPITPHICE  741
            +  ++ +FNT IA  M +VN         ++ E+  F+  + +F   + +++P++PH+ E
Sbjct  694  EQVDQMKFNTAIAQLMVFVNA--------ANKEDKLFSDYAKGF---VQLIAPFAPHLGE  742

Query  742  ELWAN-AGYEGSISTVAWPEFDESALVTDELLIIIQVNGKMRAKLSVAASASKEEIEKSA  800
            ELW   ++   SIS V+WP +DES LV +++ I++Q++GK++AKL VA   S+EE++  A
Sbjct  743  ELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVA  802

Query  801  LGHENVTKHTEGKDIKKIIVVPGKLVNIVAK  831
            L++E+V  +  GKDI K+I VP KLVNIV K
Sbjct  803  LANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

1251) leuS in NC_018079


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  538 bits (2029),  Expect = 8e-154, Method: Compositional matrix adjust.
 Identities = 355/865 (42%), Positives = 552/865 (64%), Gaps = 46/865 (5%)

Query  5    YRPEEIESKVQQHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIA  63
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADELLNDLDTLDHWPDTVKTMQRNWIGRSEGVEITFNVENYDQT  242
            V RK + QW +KITAYA+ LL+DL+ +D WP+++K MQRNWIG+S G ++TF+V + D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGATYLAVAAGHPLAQ--KAAENNPELATFIDECR-NTKVAEADMATME  299
            +TV+TTRPDT+ GATY  +A+ H+L +   ++++   +A +  +   ++ +A +D+A  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGVATGFYAKHPLTGEAIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFATKYNLPIKAV  359
            K GV TG YA +P+ G  +PVW A++VL  YGTGA+MAVP+HD+RD EFA ++NL I +V
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  360  ILAADGSEPDLSEQALTEKGTLFNSGEFSGLSFEDGFNAIADKLASLGVGERKVNYRLRD  419
            + +++  E+ ++E++L  ++ +++     GL    ++  + + L + GVG+ +V YRLRD
Sbjct  362  LEGGNVEEAAFTEDGLHINSDFLD-----GLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMVTLEDGTVMPTPEDQLPVILP--EDVVMDGIT-SPIKADPEWAKT  476
            W  SRQRYWG PIP++  EDGT  + PE +LP++LP   D+   G   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  T-VNGQPALRETDTFDTFMESSWYYARYTCPQYQEGMLDSDAANYWLPVDIYIGGIEHAI  535
            T  +G  + RET+T      SSWYY RY  P+  E + D +  + WLPVDIY+GG EHA+
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGANGERNWVSPVDAIVER  595
            +HLLY RF HK++ D G+V + EP ++L+ QGM+L+ +  Y ++ G    + + D +  R
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS--YRDSRGA---LVATDKVEKR  591

Query  596  DEKGRIVKAKDAEGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMT  655
            D  G +     +E  E    + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D +
Sbjct  592  D--GSFFHVETGEELE---QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  656  LEWQESGVEGANRFLKRVWKLVYEHTAQGDAPALNVAALTEDQQALRRDVHKTIAKVTDD  715
            + W E G+EG+ +FL RV +L+       + ++           AL +  + T+  VT++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLITTKEITEENSG-----------ALDKVYNETVKAVTEQ  695

Query  716  IGRRQTFNTAIAAIMELMNKLAKAPQEGEQDRALMREALLAVVRMLNPFTPHVSFTLWQE  775
            +++ + FNTAIA +M ++N        ++++  L  +   + V+++ PF+PH++  LWQ 
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  776  LKGEGD-IDNAPWPVADESAMVENTTLVVVQVNGKVRGKITVAVDATEEQVRERAGQEHL  834
            L + G+ I   PWP  DES +VEN   +VVQ++GKV++K+ VA D + E+++E A  ++ 
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  835  VAKYLEGVTVRKVIYVPGKLLNLVV  859
            V   + G  + KVI VP KL+N+V+
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVI  832

1252) leuS in NC_013416


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  538 bits (2029),  Expect = 9e-154, Method: Compositional matrix adjust.
 Identities = 358/866 (42%), Positives = 559/866 (65%), Gaps = 46/866 (5%)

Query  5    YRPDLLEPEVQKFWQDNKTFKAVQDNNKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVVS  63
            Y    +EP  Q FW DN TFK+  D +K K+Y L M+PYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMIGKNVLQPMGWDAFGLPAEGAAVKNNTAPAKWTYENIAYMKNQLQLLGFSYDWDR  123
            R++R  G NVL+PMGWDAFGLPAE  A+     PA  T ENIA  K Q++ LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVTTCRPEYYKWEQWFFTELYKKGLVYKKTSTVNWCPNDKTVLANEQV-HEGCCWRCDTP  182
            EV T  P+YYKW QW+FT LY KGL Y     VNW  +  T +ANE+V  +G   R + P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VEQKEIPQWFIKITDYAEQLLNCLDELPQWPETVKTMQRNWIGRSEGVEITFDIKDTNEK  242
            V +K + QW +KIT YAE+LL+ L+E+ +WPE++K MQRNWIG+S G ++TF +KDT+  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LAVYTTRPDTFYGVSYv--avaaahplatlaaQNNPALAQFIQEAK-NTKVAEADIATME  299
            ++V+TTRPDT++G +Y   A   A   A  ++++  A+A++ ++A  ++ +A +D+A  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGMATGLYAVHPLTGELLPVWVANFVLMHYGTGAVMAVPAHDQRDYEFAQKYGLPIKQV  359
            K G+ TG YA++P+ G  +PVW+A++VL  YGTGA+MAVPAHD+RD EFA+++ L I  V
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  360  IEPIHGEEIDLTKQAFTEHGKLIHSAEFDGLEFGAAFSGIADKLEQLGMGKRQVNYRLRD  419
            +E  + EE      AFTE+G  I+S  +DGL+ ++A++ + + LE  G+G+ +V YRLRD
Sbjct  362  LEGGNVEE-----AAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMLTLENGDVVPAPMKDLPIILP--EDVVMNGV-NSPIKADPEWAKT  476
            W  SRQRYWG PIP++  E+G   + P  +LP++LP   D+  +G  +SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  TYQGKL-ALKETDTFDTFMESSWYYARYTCPEYQQGMLNSEEANYWLPVDQYIGGIEHAT  535
            T ++ + + +ET+T      SSWYY RY  P+  + + + E  + WLPVD Y+GG EHA 
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLLYFRFFHKLLRDAGFVTSDEPANKLLCQGMVLADAFYYTSPTNERIWVSPTNVTLER  595
            +HLLY RF HK+L D G V + EP +KL+ QGM+L+ ++      + R     + V+ ++
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSR----GALVATDK  587

Query  596  DDKGRIVKATDDEGHELVHAGMTKMSKSKNNGIDPQEMVEKYGADTVRLFMMFASPAEMT  655
             +K        + G+EL +A  +KMSKS +N ++P+++VE+YGADT+R++ MF +P + +
Sbjct  588  VEKRDGSFFHVETGEELEQAP-AKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  656  LEWQESGVEGAKRFLARLWNLVFEYNKNPAKTPLNPTVLSAAQKALRRDVHKTIAKVSDD  715
            + W E G+EG+++FL R+  L+               +      AL +  + T+  V+++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLI-----------TTKEITEENSGALDKVYNETVKAVTEQ  695

Query  716  IGRRQTFNTAIAAIMELMNKLTRAPLDDEQDRAMMAEALSAVVRMLYPITPHICFHLWQE  775
            +++ + FNTAIA +M ++N         +++  + ++   + V+++ P++PH+  +LWQ 
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  776  L-GNQDIIDFAPWVEADAEAMIEDEKLIVVQVNGKVRGKVTVAADTDEDRVKAVAFADEN  834
            L ++ + I + PW   D   ++E++  IVVQ++GKV++K+ VA D   + ++ VA+A+E+
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  835  VKRFTDGMQIVKVIYVAGKLLNVVVK  860
            V+    G +I+KVI V+ KL+N+V+K
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVIK  833

1253) leuS in NC_009901


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  538 bits (2029),  Expect = 9e-154, Method: Compositional matrix adjust.
 Identities = 358/866 (42%), Positives = 556/866 (65%), Gaps = 47/866 (5%)

Query  14   YTPSEIEAKVQQHWQDTKTFEVTEDENKEKFYCLSMFPYPSGR-LHMGHVRNYTIGDVVS  72
            Y  + IE+K Q  W D  TF    D +K KFY L MFPYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  73   RYQRLQGKNVLQPIGWDSFGLPAENAAIKNNTAPAPWTYENIDYMKNQLKMLGFGYDWSR  132
            R++R QG NVL+P+GWD+FGLPAE+ A+     PA  T ENI   K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  133  EIATCTPEYYRWEQWFFTKLYEKGLVYKKTSSVNWCPNDETVLANEQVI-DGCCWRCDTT  191
            E+ T  P+YY+W QW+FTKLYEKGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  192  VEQKEIPQWFIKITEYAEELLNDIDTLEEWPEQVKTMQRNWIGRSEGIEMTFQVAGSDQS  251
            V +K + QW +KIT YAE LL+D++ + +WPE +K MQRNWIG+S G ++TF+V ++D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  252  FDIYTTRPDTVMGVTYVAIAAGHPLAEQAAINNP--ALVEFIEECKNADtteaamaamek  309
            F ++TTRPDT+ G TY  +A+ H+L +  + ++   A+ ++  +         +  A EK
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEK  302

Query  310  kGVATGLNAIHPITGKEVPIWVGNFVLMNYGTGAVMSVPAHDQRDYEFAKKYGLNIEAVI  369
             GV TG  AI+P+ GKE+P+W++++VL +YGTGA+M+VPAHD+RD EFAK++ L+I +V+
Sbjct  303  TGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL  362

Query  370  KPVDGEVDISEEAYTEKGVLFNSAEFDGLDFQAAFDAIDAKLTAEGKGKRQVNFRLRDWG  429
                   ++ E A+TE G+ +NS  +DGLD  +A+  +   L AEG G+ +V +RLRDW 
Sbjct  363  ----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWL  418

Query  430  VSRQRYWGAPIPMVTLADGTVMPTPEDQLPVILP--EDVVMDGI-QSPIKSDKEWAKTTI  486
             SRQRYWG PIP++   DGT  + PE +LP++LP   D+   G  +SP+ +  +W   T 
Sbjct  419  FSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTR  478

Query  487  -NGQEAFRETDTFDTFMESSWYYARYCSPHADEML-DPAKANYWLPVDQYIGGIEHACMH  544
             +G  + RET+T      SSWYY RY  PH  E L D    + WLPVD Y+GG EHA +H
Sbjct  479  EDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLH  538

Query  545  LLYFRFFHKLLRDTGLVNSNEPAKRLLTQGMVLADAYYYNNEKGARVWVAPSDVTVQETD  604
            LLY RF HK+L D G+V ++EP ++L+ QGM+L+ +  Y + +GA        V+ +  +
Sbjct  539  LLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS--YRDSRGAL-------VATDKVE  589

Query  605  DKGRTVKAVDSEGHELVYTGMSKMSKSKNNGIDPQEMVDKYGADTVRLFMMFAAPPELTL  664
             ++ +   V++ G+EL   + +KMSKS +N ++P+++V++YGADT+R++ MF +P + ++
Sbjct  590  KRDGSFFHVET-GEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASI  647

Query  665  EWQESSVEGAHRFIKRLWK-TAHDHIANGTTAELDVKSLNAAQKELRRELHKTIAKVGDD  723
             W E ++EG+++F+ R+ +  +  +I++  ++ LD            +  + T+  V ++
Sbjct  648  AWSEEGLEGSRKFLDRVYRLITTKEITEENSGALD------------KVYNETVKAVTEQ  695

Query  724  IERRQMFNTAIASIMELMNRLQKAPSETDQDKALMQEALNAVIRLLYPIIPHTCFVLWNE  783
            +++ + FNTAIA +M ++N        ++++  L  +  ++ ++L+ P+ PH    LW+ 
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  784  LGNQG-AIEEVLWPEVDESALVEDSKLIIVQVNGKLRAKITVAADASKeeveaagmaeeg  842
            L   G +I  V WP  DES LVE+   I+VQ++GK++AK+ VA D S+EE++  ++A+E 
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  843  vvKHTEDKTVRKVIYVPGKLLNIVAN  868
            V  +  +K + KVI VP KL+NIV +
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVIK  833

1254) leuS in NC_018019


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  537 bits (2027),  Expect = 1e-153, Method: Compositional matrix adjust.
 Identities = 353/742 (48%), Positives = 510/742 (69%), Gaps = 68/742 (9%)

Query  224  LVYRSHSMVNWCPGLGTVLANEEVTADGRSERGIFPVFRKNLSQWMMRITAYSDRLIDDL  283
            L Y ++  VNW   LGT +ANEEV +DG SERG +PV RK + QWM++ITAY++RL++DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  284  DALDWPDKVKSMQRNWIGRSRGAEVDFDV--LGHTITVFTTRPDTLFGASYMVLAPEHEL  341
            + +DWP+ +K MQRNWIG+S GA+V F V   +  +TVFTTRPDTLFGA+Y VLAPEH L
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  342  VDALVAAGTNSYDGVDPRWTFEQSCPADAVKAYRASIAAKSDLERQE-NKEKTGVYLGVN  400
            VDA+ +++                  A+AV  Y+   + KSDL R +  KEKTGV  G  
Sbjct  268  VDAITTSD-----------------QAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSY  310

Query  401  AVNPVNGESIPVFIGDYVLTGYGTGAIMAVPAHDTRDYEFATEFGLPIREVVAGGNVAEE  460
            A+NPVNG  +PV I+DYVL++YGTGAIMAVPAHD RD EFA +F L I  V+ GGNV E 
Sbjct  311  AINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEA  370

Query  461  AYTESGVAVNSANDEGLDINGLDKQEAIARVIEWLVDKQKGSEKIQYKLRDWLFARQRYW  520
            A+TE G+ +NS       ++GLDK  AIA+++EWL     G+E++ Y+LRDWLF+RQRYW
Sbjct  371  AFTEDGLHINSDF-----LDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYW  425

Query  521  GEPFPVVYDADGVAHALPESMLPVELPEVEDYKPVSFDPDDADSEPQPPLAKATEWTQVE  580
            GEP+P++   DG + A+PES LP+ LP   D +P         +  ++PLA+ T+W +V 
Sbjct  426  GEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTDWLEVT  477

Query  581  LDLGDGLKTYTRDTNVMPQWAGSSWYQLRYIDPTNNKQFCDIENERYWTGPRGENdlggv  640
             +  DG+K   R+TN MPQWAGSSWY LRYIDP N  ++ D E  + W           V
Sbjct  478  RE--DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLP---------V  525

Query  641  dlyvggvEHAVLHLLYSRFWHKVLFDLGYVTSGEPYRRLFNQGYIQAFAYTDSRGVYVPA  700
            D+YVGG EHAVLHLLY+RFWHKVL+DLG V + EP+++LFNQG I + +Y DSRG  V++
Sbjct  526  DIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVAT  585

Query  701  AEVEEKDGKFFY--QGEEVNQEYGKMGKSLKNAVAPDEICSDFGADTLRVYEMAMGPLDT  758
              VE +DG FF    GEE++Q  +KM+KSLKN V PD++  ++GADTLRVYEM MGPLD+
Sbjct  586  DKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  759  SRPWATKDVIGAHRFLQRLWRLVVSEDDGSVVVTDAGLADDDLKQLHRTIAGMRDDYEGL  818
            S +W+  ++ G+++FL+R+ RL+ + +   +   ++G  D   K  + T+ ++ ++ + +
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLITTKE---ITEENSGALD---KVYNETVKAVTEQVDQM  699

Query  819  RINTVVAKAIEYVNYLTK------NYAKGAPRAAVEPLVIMVAPVAPHIAEELWKRL-GH  871
            ++NT +A+ + +VN   K      +YAKG        +V ++AP APH++EELW+ L + 
Sbjct  700  KFNTAIAQLMVFVNAANKEDKLFSDYAKG--------FVQLIAPFAPHLGEELWQALTAS  751

Query  872  EETITFVAFPDYDEKWLVDDEVEMPIQINGKVRARIMVPADATQDQIVEIALAEPTVQSH  931
             E+I++V+ P YDE  LV+++VE+ +QI+GKV+A+++V+ D +++++ E+ALA+  VQ++
Sbjct  752  GESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAE  811

Query  932  LEGKNLFKQIVVPGRMVNLVIK  953
            + GK+++K I VP ++VN+VIK
Sbjct  812  IAGKDIIKVIAVPNKLVNIVIK  833


 Score =  140 bits (516),  Expect = 3e-34, Method: Compositional matrix adjust.
 Identities = 81/149 (55%), Positives = 106/149 (72%), Gaps = 10/149 (6%)

Query  21   GDIERTWQQFWIDNGTFNAPNPVGDLAVAGQGLPEDKLFVQDMFPYPSGAGLHVGHPLGY  80
              IE  WQ FW DN TF++          G + +  K++  DMFPYPSGAGLHVGHP GY
Sbjct  7    TAIEPKWQAFWADNHTFKT----------GTDASKPKFYALDMFPYPSGAGLHVGHPEGY  56

Query  81   IATDVFARFNRMLGKNVLHTLGYDAFGLPAEQYAIQTGTHPRATTMSNIANMQRQLSALG  140
             ATD+++RF+R  G NVLH +G DAFGLPAEQYA++TG +P   T  NIAN +RQ++ALG
Sbjct  57   TATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALG  116

Query  141  LGHDPRRSVATTDPEFYKWTQWIFLQIFN  169
            ++ D  R V TTDP++YKWTQWIF ++++
Sbjct  117  FSYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1255) leuS in NC_017096


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  537 bits (2027),  Expect = 1e-153, Method: Compositional matrix adjust.
 Identities = 377/831 (46%), Positives = 533/831 (65%), Gaps = 58/831 (6%)

Query  24   FKAEDFSEKPKFYILVMFPYPSGSGLHVGHCRNYIPADTYARYKRMQGFNVLHPIGYDAF  83
            FK+   + KPKFY L MFPYPSG+GLHVGH   Y ++D  +R+KR QG NVLHP+G DAF
Sbjct  23   FKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSRFKRAQGHNVLHPMGWDAF  82

Query  84   GLPAENYAIEHGIHPRESTYRNIENFRRQLKMLGLSYDWDREFATSDPEYYKWTEWFFEL  143
            GLPAE+YA++ G +P E T  NI NF+RQ++ LG+SYDWDRE  T+DP+YYKWT+W+F  
Sbjct  83   GLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTK  142

Query  144  LFKRGLAYQDRSFQWWCPHCKTVLANEQII-DGKCWRCGTPVVKKELKEWFFRITHYADK  202
            L+ +GLAY+      W  +  T +ANE+++ DG   R G PVV+K +++W ++IT YA++
Sbjct  143  LYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAER  202

Query  203  LLEGLDRIDWPERIKSMQRNWIGRSEGAEITFKGVGPDGTEYDLPVFTTRIDTIFGVTFL  262
            LLE+L+ +DWPE IK MQRNWIG+S GA++TFK     +T+ D+ VFTTR DT+FG T+ 
Sbjct  203  LLEDLEEVDWPESIKDMQRNWIGKSTGANVTFK---VKDTDKDFTVFTTRPDTLFGATYA  259

Query  263  AIAPEHPLVMKLTREDKVEEVKKYIEEALRKFETERLSTEKEKTGVFTGCFARNPFTDEL  322
             +APEH+LV  +T  D+ E V  Y  +A  K +  R    KEKTGV TG +A NP  +  
Sbjct  260  VLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAINPVNGKE  319

Query  323  VPIYVGDYVVYSYGTGAVMGVPAHDERDFQFAKKHNLPIKIVISKDGSLVETLEEAFTED  382
            +P+ ++DYV+ SYGTGA+M+VPAHDERD +FAK+ NL I  V+  +G+ VE  E AFTED
Sbjct  320  MPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL--EGGNVE--EAAFTED  375

Query  383  GILINSNGFSGLRSDEARKKLTKYAEEHGFGRGVVRYKIRDWLISRQRYWGAPIPIIHCP  442
            G+ INS+ + GL    A  K+    E +G G   V Y++RDWL+SRQRYWG PIPIIH  
Sbjct  376  GLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWE  435

Query  443  EHGAvpvpeedlpvllpdevdFSPRDTGESPLANDPDFVNTSCPICGKPSRRETDTQDGF  502
            +  + +VPE +LP++LP   D+ P +TGESPLAN  D ++ +     K +RRET+T    
Sbjct  436  DGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK-GRRETNTMPQW  494

Query  503  ACSSWYFLRYADPHNDKAPFDKEKVKYWLPVDLYIGGAEHAVMHLLYARFYTMVMYDAGL  562
            A SSWY+LRY DPHN     D E +K WLPVD+Y+GGAEHAV+HLLYARF   V+YD G+
Sbjct  495  AGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGV  554

Query  563  IDFDEPFKKLLNQGMILGA---------------------------------DHQKMSKS  589
            +   EPF+KL+NQGMILG+                                    KMSKS
Sbjct  555  VPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKS  614

Query  590  RGNVVNPDDVIKEYGADTLRAYILFIGPLDTDAPWSTEGINGVNRFIKRMWNLFIQLEDK  649
              NVVNPDDV+ +YGADTLR Y +F+GPLD+  +WS EG++G  +F+ R+  L+      
Sbjct  615  LKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLI-----T  669

Query  650  SttkekpiekeielitDKMIVKVTEQIERFKFNTMISSFMEWLNFLSKITQEDAEVMETK  709
            +          ++ + +  +  VTEQ+++ KFNT I+ +M    F++   +ED      K
Sbjct  670  TKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLM---VFVNAANKED------K  720

Query  710  AYREAVQTFLTMIAPATPFVAEELYHRLGGTG-SIHKKEWPK-PKGIYKEEYVTIIVQVN  767
             + +  + F+ +IAP +P ++EEL + L ++G SI    WP    +   E+ V I+VQ++
Sbjct  721  LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIK  780

Query  768  GKLRDKIEVEAGSELEDVLDLVKKSDKITRLGIDFNKAKYIFVKDKLINIV  818
            GK++ K+ V  +   E++ ++   ++K+     + +  K I V +KL+NIV
Sbjct  781  GKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIV  831

1256) Tthe_2364 in NC_014410


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  537 bits (2026),  Expect = 1e-153, Method: Compositional matrix adjust.
 Identities = 363/829 (44%), Positives = 529/829 (64%), Gaps = 57/829 (6%)

Query  6    DIDRKWQKKWEETELYKFNPQNMDKKLYCLEMFSYPSGAKLHAGHWYNYGPADSWARMKR  65
             I+ KWQ  W + + +K   +    K+Y L+MF+YPSGA LH GH   Y ++D  +R KR
Sbjct  8    AIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSRFKR  67

Query  66   MQGYEVFHPMGFDAFGLPAENYAIKTGIHPQDSTLQNIKTMERQLKEMGATFDWDYEVIT  125
             QG +V+HPMG DAFGLPAE+YA+ TG +P + T +NI    RQ++ +G ++DWD EV T
Sbjct  68   AQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDREVNT  127

Query  126  CLPDYYKWTQWVFLQLYKKGLAYRKKAPVNWCPSCKTVLANEQVV-EGTCERCGSEVTKK  184
              P+YYKWTQW+F +LY KGLAY    PVNW     T +ANE+V+ +GT ER G  V +K
Sbjct  128  TDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRK  187

Query  185  DLTQWFLKITDYAeellekldeldWPEKTKMMQRNWIGKSDGAEIEFKVDGKDISFKVFT  244
             + QW LKIT YAE LLE L+E+DWPE  K MQRNWIGKS GA++ FKV + D  F VFT
Sbjct  188  PMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFT  247

Query  245  TRADTLYGVTYVVLAPENEIVDQITTDKYRRNVEEYKEYARKQSEIERLSTEKEKTGVFT  304
            TR+DTL+G TY VLAPE+ +VD ITT      V +YK  A  +S++ R    KEKTGV T
Sbjct  248  TRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVWT  307

Query  305  GAYAIHPITGEKLPIWISDYVLATYGTGCVMAVPAHDERDYMFAKKYDLPMKRVIKGRDG  364
            G+YAI+P+ G  +P+WI+DYVLA+YGTG +MAVPAHDERD  FAK+++L +  V+ G + 
Sbjct  308  GSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEG-GN  366

Query  365  VDDSLPFVEYGILVDSGDFTGSKSEDARIEIVKMLEKEGKGSLKVNYRLRDWLVSRQRYW  424
            V+++ +F E G+ ++S+ + G     A   +V  LE EG G+ +V YRLRDWL SRQRYW
Sbjct  367  VEEA-AFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYW  425

Query  425  GAPIPIIHCEKCGlvpvpeedlpvllpYNVEFSPD--GESPLKKSEEFMNTTCPKCGGKA  482
            G PIPIIH E     +VPE +LP++LP   ++ P   GESPL +  + ++ T    G K+
Sbjct  426  GEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED-GVKG  484

Query  483  LRDPDTLDTFVDSSWYFLRYPDNKNDKEPFNKELIDKMLPVDKYIGGAEHACMHLLYARF  542
             R+ +T+    +SSWY+LRY D  N     + EL+ + LPVD Y+GGAEHA +HLLYARF
Sbjct  485  RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARF  544

Query  543  VTKALRDLGYLDFDEPFKSLIHQGIILGP-------------------------------  571
              K L DLG +   EPF+ L++QG+ILG                                
Sbjct  545  WHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEEL  604

Query  572  --DGNKMSKSRGNTISPDEYINEYGSDVFRMYLMFGFAFTEGGPWNDDGIKAMSRFISRI  629
                 KMSKS  N ++PD+ +++YG+D +R+Y MF  ++  + +W+++G+ +  +F+ R+
Sbjct  605  EQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRV  664

Query  630  ERLIDKFTEDKGKSGKNEISKDEKELNYVRNYTIKSVTDDAEKFQFNTAIARIMELVNAL  689
             RLI         + K+    +   L+ V N T+K+VT++ ++ +FNTAIA++M +VNA 
Sbjct  665  YRLI---------TTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNA-  714

Query  690  YKYDGEVENKNMKLYEETIADLIRVLAPFAPHFSEEMWERMGYSYSVFN-QKWPEYDDKA  748
                    NK+ KL+ +   ++++++APFAPH++EE+W+ +  S   ++   WP YD+  
Sbjct  715  -------ANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESK  767

Query  749  LVKDTIEIAIQVNGKVRGRLEIPSGATEKEIQDKALVVESIKQFIEGKE  797
            LV + +EI +Q++GKV+++L ++ + +  E+Q+ AL  E ++  I GK+
Sbjct  768  LVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKD  816

1257) Thethe_02420 in NC_019970


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  537 bits (2026),  Expect = 1e-153, Method: Compositional matrix adjust.
 Identities = 363/829 (44%), Positives = 529/829 (64%), Gaps = 57/829 (6%)

Query  6    DIDRKWQKKWEETELYKFNPQNMDKKLYCLEMFSYPSGAKLHAGHWYNYGPADSWARMKR  65
             I+ KWQ  W + + +K   +    K+Y L+MF+YPSGA LH GH   Y ++D  +R KR
Sbjct  8    AIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSRFKR  67

Query  66   MQGYEVFHPMGFDAFGLPAENYAIKTGIHPQDSTLQNIKTMERQLKEMGATFDWDYEVIT  125
             QG +V+HPMG DAFGLPAE+YA+ TG +P + T +NI    RQ++ +G ++DWD EV T
Sbjct  68   AQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDREVNT  127

Query  126  CLPDYYKWTQWVFLQLYKKGLAYRKKAPVNWCPSCKTVLANEQVV-EGTCERCGSEVTKK  184
              P+YYKWTQW+F +LY KGLAY    PVNW     T +ANE+V+ +GT ER G  V +K
Sbjct  128  TDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRK  187

Query  185  DLTQWFLKITDYAeellekldeldWPEKTKMMQRNWIGKSDGAEIEFKVDGKDISFKVFT  244
             + QW LKIT YAE LLE L+E+DWPE  K MQRNWIGKS GA++ FKV + D  F VFT
Sbjct  188  PMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFT  247

Query  245  TRADTLYGVTYVVLAPENEIVDQITTDKYRRNVEEYKEYARKQSEIERLSTEKEKTGVFT  304
            TR+DTL+G TY VLAPE+ +VD ITT      V +YK  A  +S++ R    KEKTGV T
Sbjct  248  TRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVWT  307

Query  305  GAYAIHPITGEKLPIWISDYVLATYGTGCVMAVPAHDERDYMFAKKYDLPMKRVIKGRDG  364
            G+YAI+P+ G  +P+WI+DYVLA+YGTG +MAVPAHDERD  FAK+++L +  V+ G + 
Sbjct  308  GSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEG-GN  366

Query  365  VDDSLPFVEYGILVDSGDFTGSKSEDARIEIVKMLEKEGKGSLKVNYRLRDWLVSRQRYW  424
            V+++ +F E G+ ++S+ + G     A   +V  LE EG G+ +V YRLRDWL SRQRYW
Sbjct  367  VEEA-AFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYW  425

Query  425  GAPIPIIHCEKCGlvpvpeedlpvllpYNVEFSPD--GESPLKKSEEFMNTTCPKCGGKA  482
            G PIPIIH E     +VPE +LP++LP   ++ P   GESPL +  + ++ T    G K+
Sbjct  426  GEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED-GVKG  484

Query  483  LRDPDTLDTFVDSSWYFLRYPDNKNDKEPFNKELIDKMLPVDKYIGGAEHACMHLLYARF  542
             R+ +T+    +SSWY+LRY D  N     + EL+ + LPVD Y+GGAEHA +HLLYARF
Sbjct  485  RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARF  544

Query  543  VTKALRDLGYLDFDEPFKSLIHQGIILGP-------------------------------  571
              K L DLG +   EPF+ L++QG+ILG                                
Sbjct  545  WHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEEL  604

Query  572  --DGNKMSKSRGNTISPDEYINEYGSDVFRMYLMFGFAFTEGGPWNDDGIKAMSRFISRI  629
                 KMSKS  N ++PD+ +++YG+D +R+Y MF  ++  + +W+++G+ +  +F+ R+
Sbjct  605  EQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRV  664

Query  630  ERLIDKFTEDKGKSGKNEISKDEKELNYVRNYTIKSVTDDAEKFQFNTAIARIMELVNAL  689
             RLI         + K+    +   L+ V N T+K+VT++ ++ +FNTAIA++M +VNA 
Sbjct  665  YRLI---------TTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNA-  714

Query  690  YKYDGEVENKNMKLYEETIADLIRVLAPFAPHFSEEMWERMGYSYSVFN-QKWPEYDDKA  748
                    NK+ KL+ +   ++++++APFAPH++EE+W+ +  S   ++   WP YD+  
Sbjct  715  -------ANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESK  767

Query  749  LVKDTIEIAIQVNGKVRGRLEIPSGATEKEIQDKALVVESIKQFIEGKE  797
            LV + +EI +Q++GKV+++L ++ + +  E+Q+ AL  E ++  I GK+
Sbjct  768  LVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKD  816

1258) D7S_01126 in NC_017846


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  537 bits (2027),  Expect = 1e-153, Method: Compositional matrix adjust.
 Identities = 361/866 (42%), Positives = 555/866 (65%), Gaps = 46/866 (5%)

Query  5    YRPDLLEPEVQKFWQDNKTFKAVQDNNKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVVS  63
            Y    +EP  Q FW DN TFK+  D +K K+Y L M+PYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMIGKNVLQPMGWDAFGLPAEGAAVKNNTAPAKWTYENIAYMKNQLQLLGFSYDWDR  123
            R++R  G NVL+PMGWDAFGLPAE  A+     PA  T ENIA  K Q++ LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVTTCRPEYYKWEQWFFTELYKKGLVYKKTSTVNWCPNDKTVLANEQV-HEGCCWRCDTP  182
            EV T  P+YYKW QW+FT LY KGL Y     VNW  +  T +ANE+V  +G   R + P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VEQKEIPQWFIKITDYAEQLLNCLDELPQWPETVKTMQRNWIGRSEGVEITFDIKDTNEK  242
            V +K + QW +KIT YAE+LL+ L+E+ +WPE++K MQRNWIG+S G ++TF +KDT+  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LAVYTTRPDTFYGVSYv--avaaahplatlaaQNNPALAQFIQEAK-NTKVAEADIATME  299
            ++V+TTRPDT++G +Y   A   A   A  ++++  A+A++ ++A  ++ +A +D+A  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGMATGLYAVHPLTGELLPVWVANFVLMHYGTGAVMAVPAHDQRDYEFAQKYGLPIKQV  359
            K G+ TG YA++P+ G  +PVW+A++VL  YGTGA+MAVPAHD+RD EFA+++ L I  V
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  360  IEPIHGEEIDLTKQAFTEHGKLIHSAEFDGLEFDAAFSGIADKLEQLGMGKRQVNYRLRD  419
            +E  + EE      AFTE+G  I+S  +DGL+  +A++ + + LE  G+G+ +V YRLRD
Sbjct  362  LEGGNVEE-----AAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMLTLENGDVVPAPMEDLPIILP--EDVVMNGV-NSPIKADPEWAKT  476
            W  SRQRYWG PIP++  E+G   + P  +LP++LP   D+  +G  +SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  TYQ-GKPALRETDTFDTFMESSWYYARYTCPEYQQGMLNSEEANYWLPVDQYIGGIEHAT  535
            T + G  + RET+T      SSWYY RY  P+  + + + E  + WLPVD Y+GG EHA 
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLLYFRFFHKLLRDAGFVTSDEPANKLLCQGMVLADAFYYTSPTNERIWVSPTKVTLER  595
            +HLLY RF HK+L D G V + EP +KL+ QGM+L+ ++      + R     + V+ ++
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSR----GALVATDK  587

Query  596  DDKGRIVKATDDEGHELVHAGMTKMSKSKNNGIDPQEMVEKYGADTVRLFMMFASPAEMT  655
             +K        + G+EL +A  +KMSKS +N ++P+++VE+YGADT+R++ MF +P + +
Sbjct  588  VEKRDGSFFHVETGEELEQAP-AKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  656  LEWQESGVEGAKRFLARVWNLVFEYNKNPAKTPLNPTALSAAQKALCRDVHKTIAKVSDD  715
            + W E G+EG+++FL RV  L+                      AL +  + T+  V+++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLI-----------TTKEITEENSGALDKVYNETVKAVTEQ  695

Query  716  IGRRQTFNTAIAAIMELMNKLTRAPLDDEQDRAMMAEALSAVVRMLYPITPHICFRLWQE  775
            +++ + FNTAIA +M ++N         +++  + ++   + V+++ P++PH+   LWQ 
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  776  L-GNQDIIDFAPWVEADAEAMIEDEKLIVVQVNGKVRGKVTVAADADEDTVKAVAFADEN  834
            L ++ + I + PW   D   ++E++  IVVQ++GKV++K+ VA D   + ++ VA+A+E+
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  835  VKRFTDGMQIVKVIYVAGKLLNVVVK  860
            V+    G +I+KVI V+ KL+N+V+K
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVIK  833

1259) Despr_1832 in NC_014972


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  537 bits (2026),  Expect = 1e-153, Method: Compositional matrix adjust.
 Identities = 350/837 (42%), Positives = 533/837 (64%), Gaps = 68/837 (8%)

Query  27   KVSHQPGRPKYYVLEMFPYPSGR-IHMGHVRNYSIGDVIARYKRMQGFNVLHPMGWDAFG  85
            K + ++++PK+Y L+MFPYPSG  +H+GH   Y+  D+++R+KR QG NVLHPMGWDAFG
Sbjct  24   KTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSRFKRAQGHNVLHPMGWDAFG  83

Query  86   LPAENAAMKRGIHPASWTYENIDYMRGQLKAMGLSYDWDRELATCGPEYYRWEQQLFLKM  145
            LPAE+ AM  G +PA  T ENI   + Q++A+G+SYDWDRE+ T +P+YY+W Q +F K+
Sbjct  84   LPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKL  143

Query  146  LERGLIYRKETTVNWCDDCQTVLAREQVI-DGTCWRCDQPVLPKTMHGWFFKITDYAEEL  204
             E+GL Y  E  VNW ++  T +A E+V+ DGT  R + PV+ K M+ W +KIT YAE L
Sbjct  144  YEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERL  203

Query  205  LADLDKLGGWPEKVVTMQRNWIGKSTGLACDFKVEGTDQTITIFTTRPDTIFGVTFMSLA  264
            L DL+ + +WPE +  MQRNWIGKSTG    FKV +TD+ +T+FTTRPDT+FG T+  LA
Sbjct  204  LEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLA  262

Query  265  VEHPLLKTLTAGKSQEAQVRTFIEETMVAKQRASLDQEVEKRGVFTGSYCTNPFTGERVP  324
             EH+L+ ++T++   EA V  +  ++ +  + A  D   EK GV TGSY  NP  G  +P
Sbjct  263  PEHALVDAITTSDQAEA-VADYKRQASLKSDLARTDLAKEKTGVWTGSYAINPVNGKEMP  321

Query  325  IYAANFVLMEYGTGAVMAVPAHDQRDFEFARKYDLPIRVVVQPEGDSLDPVTMTAASEGP  384
            +  A++VL  YGTGA+MAVPAHD+RD EFA++++L I  V+  EG++++  + T      
Sbjct  322  VWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL--EGGNVEEAAFTED----  375

Query  385  GMLVASGAFTGMDSLSaqqaiidhahqaGFGRPHVTYRLRDWGISRQRYWGAPIPVIHCD  444
            G+ + S+ + G+D  SA   +++  +  G G  +VTYRLRDW +SRQRYWG PIP+IH +
Sbjct  376  GLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWE  435

Query  445  SCGIVPVPESDLPILLPGAGE--PKGS-HSPLHQQEAFIATACPRCGKPARRETDTLDTF  501
                 +VPES+LP++LP + +  P G+ +SPL +    +  +     K +RRET+T+   
Sbjct  436  DGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK-GRRETNTMPQW  494

Query  502  VESSWYFARYTNPGLDTAPIDREAAAYWLPVDQYIGGVEHAILHLLYARFFTKMLRDLGY  561
              SSWY+ RY +P       D E    WLPVD Y+GG EHA+LHLLYARF  K+L DLG 
Sbjct  495  AGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGV  554

Query  562  LSVDEPFTNLLTQGMVI-------------------KDG---------------AKMSKS  587
            ++  EPF +L+ QGM++                   +DG               AKMSKS
Sbjct  555  VPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKS  614

Query  588  KGNVVDPNELIQQYGADTVRLFSLFAAPPERDLEWNAQGVEGASRFLNRVYRLVVQNLSC  647
              NVV+P+++++QYGADT+R++ +F +P +  + W+ +G+EG+ +FL+RVYRL+  +   
Sbjct  615  LKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEIT  674

Query  648  FQQPAAVDLTALNEPSRALYRKTHQTIRRVTESIESNFHFNTAISGVMELVNLATTQTDE  707
             ++++A+D          +Y   ++T++ VTE ++ +  FNTAI+ +M +VN A  +   
Sbjct  675  EENSGALD---------KVY---NETVKAVTEQVD-QMKFNTAIAQLMVFVNAANKEDK-  720

Query  708  PIDPAVQRETLETILTLLFPMVPHFCEELW-AISGHTRQLHHTSWPAFNIEAAKEDEITI  766
                 +  +    ++ L+ P  PH+ EELW A+++    +   +WP+++     E+++ I
Sbjct  721  -----LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEI  775

Query  767  VVQVNGKVRAKLQVPADIDDQTLRQQALSEEKIAKLLDDKSPKKVIVVQKKLVNIVL  823
            VVQ++GKV+AKL V+ D+  + L++ AL++EK+   + +K   KVI V +KLVNIV+
Sbjct  776  VVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

1260) DGI_1902 in NC_022444


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  537 bits (2028),  Expect = 1e-153, Method: Compositional matrix adjust.
 Identities = 362/873 (42%), Positives = 554/873 (64%), Gaps = 82/873 (9%)

Query  5    YSPESIEAKWQGIWEERKVFHCETDPSRPKYYVLEMFPYPSGR-IHIGHARVYSIGDVLA  63
            Y   +IE+KWQ++W +   F   TD+S+PK+Y L+MFPYPSG  +H+GH+  Y+  D+L+
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYKRMQGFNVLHPMGWDAFGMPAENAAIKHGVHPAGWTFENIDTMRVQLQRMGYSLDWRR  123
            R+KR QG NVLHPMGWDAFG+PAE+ A+  G +PA  T ENI   + Q++ +G+S DW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVTTCVPEYYRWEQLFFLKFLEKGLAYRKQAPQNWCETCHTVLANEQVI-DGQCWRCDSQ  182
            EV T  P+YY+W Q +F K+ EKGLAY  + P NW E   T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VVQRDLTQWFLRITDYAQEllddldTLEQGWPERVVSMQRNWIGRSTGAYISFDLERPAE  242
            VV++ + QW L+IT YA+ LL+DL+ ++  WPE +  MQRNWIG+STGA ++F +     
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD--WPESIKDMQRNWIGKSTGANVTFKV----K  237

Query  243  DGTANIRVFTTRPDTLFGATFMSLAAEHPLVEQLIKDSPNAEAVRAFCTKVKNTDRLQRG  302
            D   ++ VFTTRPDTLFGAT+  LA+EH+LV+  I  S +AEAV  +  +      L R 
Sbjct  238  DTDKDFTVFTTRPDTLFGATYAVLAPEHALVDA-ITTSDQAEAVADYKRQASLKSDLART  296

Query  303  AEDQEKEGIFTGAYCINPLTGRRMPIWVANFVLMGYGTGAVMAVPAHDQRDFEFATKYDL  362
               +EK G+ TG+Y INP+ G+ MP+W+A++VL +YGTGA+MAVPAHD+RD EFA +++L
Sbjct  297  DLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNL  356

Query  363  PMQVVIQPAGDTLDPAAMTAAYVDPGVLVNSGAFDGQPNEEAKKAIVEHLQSQDKAEPAV  422
             +  V++  G+ ++     AA+ + G+ +NS+ +DG  +  A   +VE L++++ ++  V
Sbjct  357  DIIPVLE--GGNVE----EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENV  410

Query  423  TWRLRDWNISRQRYWGAPIPVLYCDDCGVVPEKEENLPVVLPL--DVKTREDGRSPLPDY  480
            T RLRDW +SRQRYWG PIP++  +D    +  E +LP+VLP+  D++    G SPL++ 
Sbjct  411  TYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANV  470

Query  481  APFVQAPCPRCGKPARRETDTMDTFVESSWYYIRYSAPWEHGRPFDPEALKYWLPVDQYI  540
            +  ++       K +RRET+TM     SSWYY+RY  P +  +  D E LK WLPVD Y+
Sbjct  471  TDWLEVTREDGVK-GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYV  529

Query  541  GGVEHAILHLLYSRFFVKALRDLGWLEFDEPFKALLAQGMVL------------------  582
            GG EHA+LHLLY+RF  K L DLG +   EPF+ L+ QGM+L                  
Sbjct  530  GGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVE  589

Query  583  -KDGT---------------KMSKSKGNVVSPDEMTARYGADAVRCFLLFAAPPERDLDW  626
             +DG+               KMSKS  NVV+PD++  +YGAD++R + +F +P +  + W
Sbjct  590  KRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAW  649

Query  627  SDTGIEGSFRFVQRVWRLIDELRHSLPALSAAGSTTADVAEAGLPEAAELRHKEHVTIQK  686
            S+ G+EGS +F++RV RLI               TT +++E    +++ L    + T++ 
Sbjct  650  SEEGLEGSRKFLDRVYRLI---------------TTKEITEE---NSGALDKVYNETVKA  691

Query  687  VAEDIGEKFQFNTAIAAVMELVNQIYQGKDALLASPAGARVLSSAVSTMLTVLAPVTPHL  746
            V+E++ ++ +FNTAIA +M +VN          A+    +++S      + ++AP +PHL
Sbjct  692  VTEQV-DQMKFNTAIAQLMVFVN----------AANKEDKLFSDYAKGFVQLIAPFAPHL  740

Query  747  CEECWSRL-GHADLLAAAPWPTVDPAALVKDAITVVVQVNGKLRARLDVAPDIAEDVIKA  805
             EE W  L + ++ ++  PWP+ D + LV + + +VVQ++GK++A+L VA D++ + ++ 
Sbjct  741  GEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQE  800

Query  806  LALAEPNVQKHLDGKTVQKVVYVPGKLVSVVVK  838
            +ALA+ +VQ ++ GK + KV+ VP KLV++V+K
Sbjct  801  VALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

1261) leuS in NC_017445


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  537 bits (2028),  Expect = 1e-153, Method: Compositional matrix adjust.
 Identities = 356/866 (42%), Positives = 549/866 (64%), Gaps = 48/866 (5%)

Query  5    YRPEEIESHVQQHWDDKQTFKVTEEEGKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIS  63
            Y    IE+  Q  W D++TFK   + +K K+Y L M+PYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYANIDYMKNQLKLLGFGYDWNR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T  NI   K Q++ LGF+YDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCQPEYYRWEQWFFTKLYEKGLVYKKTSAVNWCPHDMTVLANEQVI-DGCCWRCDSK  182
            E+ T +P+YY+W QW+FTKLYEKGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITDYADELLNDLDKLESWPEQVKTMQRNWIGRSEGVEIEFNVIDSEEQ  242
            V RK + QW +KIT YA+ LL+DL+ ++ WPE +K MQRNWIG+S G ++ F+V D++ +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LSVYTTRPDTFMGVTYLAVAAGHplaaqaamnnpalaDFIAECRNTKVAEADMA----TM  298
            ++V+TTRPDT+ G TY  +A+ H  A   A+  +  A+ +A+ +      +D+A    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEH--ALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  299  EKKGMPTGLFAKHPLTGEKVPVWVANFVLMEYGTGAVMAVPGHDQRDWEFASKYSLPIKA  358
            EK G+ TG +A +P+ G  +PVW+A++VL  YGTGA+MAVP+HD+RDWEFA +++L I +
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VILAADGSTPDLSASAMTEKGTLFNSGEFDGLSHEAGFDAIAAKLAEKGVGERKVNYRLR  418
            V+        ++  +A TE G  +NS+ +DGL   +++  +   L   GVG+ +V YRLR
Sbjct  361  VL-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  419  DWGVSRQRYWGAPIPMVTLDDGTVMPTPEDQLPVVLP--EDVVMDGIT-SPIKADAEWAK  475
            DW  SRQRYWG PIP++  +DGT  + PE +LP+VLP   D+   G   SP+   ++W  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  476  -TIVNGHPALRETDTFDTFMESSWYYARYTCPDYDKGMLNPAAANYWLPVDQYVGGIEHA  534
             T  +G  + RET+T      SSWYY RY  P+    + +    + WLPVD YVGG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  535  IMHLLYFRFFHKLLRDAGLVNSDEPAKRLLCQGMVLADAFYFTGSNGERNWVSPTDVSVE  594
            ++HLLY RF HK+L D G+V + EP ++L+ QGM+L+ ++      + R     + V+ +
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRG----ALVATD  586

Query  595  RDEKGRITKATDNDGHELVYAGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPAEM  654
            + EK   +    + G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P + 
Sbjct  587  KVEKRDGSFFHVETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  655  TLEWQESGVEGANRFLKRVWRLAFEHTEKGTATALDVDALNDDQKALRRYLHKTISKVSD  714
            ++ W E G+EG+ +FL RV RL    T K  +        +++  AL +  + T+  V++
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLI---TTKEIT--------EENSGALDKVYNETVKAVTE  694

Query  715  DIGRRQTFNTAIAAIMELMNKLARAPQESTQDRALMQEALLAVVRMLNPFTPHVSFVLWQ  774
            ++++ + FNTAIA +M ++N        + ++  L  +   + V+++ PF+PH++  LWQ
Sbjct  695  QVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  775  ALGGAGE-IDNAPWPQADEAAMVEDSLLVVVQVNGKVRGKITVAADATQEQVQARAAQEH  833
            AL ++GE I   PWP  DE+ +VE+ + +VVQ++GKV++K+ VA D ++E++Q  A  ++
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  834  LVAKYLDGVTIRKVIYVPGKLLNLVV  859
             V   + G  I KVI VP KL+N+V+
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVI  832

1262) HIBPF13900 in NC_014920


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  537 bits (2026),  Expect = 1e-153, Method: Compositional matrix adjust.
 Identities = 360/866 (42%), Positives = 557/866 (65%), Gaps = 46/866 (5%)

Query  5    YRPDMIEPKVQQYWAENKVFKAIKDESKEKYYCLSMFPYPSGR-LHMGHVRNYTIGDVIS  63
            Y    IEPK Q +WA+N  FK+  D SK K+Y L MFPYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPFGWDAFGLPAEGAAIKNKTAPAKWTYENIAYMKKQLQLLGFGFDWDR  123
            R++R  G NVL+P GWDAFGLPAE  A+     PA  T ENIA  K+Q++ LGF++DWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EIATCKPEYYKWEQWFFTELYKKGLVYKKTSTVNWCPNDETVLANEQV-HEGCCWRCDTP  182
            E+ T  P+YYKW QW+FT LY KGL Y     VNW  +  T +ANE+V  +G   R + P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VEQKEIPQWFIKITDYAEQLLGGLDTLPQWPDMVKTMQRNWIGRSEGVEITFDVANTNEK  242
            V +K + QW +KIT YAE+LL +L+ + +WP+ +K MQRNWIG+S G ++TF V +T+  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  VAVYTTRPDTFYGVSY--LGIaaahplaslaaQNNSELAAFIQEAK-NAKVAEADLATME  299
             +V+TTRPDT++G +Y  L+   A   A  ++++   +A + ++A  ++ +A +DLA  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGMATGLFAIHPLTGEKLPIWVANFVLMHYGTGAVMAVPAHDQRDFEFAQKYGLQIKQV  359
            K G+ TG +AI+P+ G  +P+W+A++VL  YGTGA+MAVPAHD+RD EFA+++ L+I  V
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  360  IEPIANEEIDLTKQAFTEHGKLVNSAEFDGKDFDGAFNGIADKLEKLGVGKRQVNYRLRD  419
            +E    EE      AFTE+G  +NS  +DG D  +A+  + + LE  GVG+ +V YRLRD
Sbjct  362  LEGGNVEE-----AAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMLTLENGDVVPAPMEDLPIILP--EDVVMDGV-KNPIKADPNWAKT  476
            W  SRQRYWG PIP++  E+G   + P  +LP++LP   D+   G   +P+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  TL-NGAPALKETDTFDTFMESSWYYARYTCPQYQNGMLDAEEANYWLPVDQYIGGIEHAT  535
            T  +G  + +ET+T      SSWYY RY  P+  + + D E  + WLPVD Y+GG EHA 
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLLYFRFFHKLLRDAGFVTSDEPADKLLCQGMVLADAFYYTSPTNERIWVSPTLVTLER  595
            +HLLY RF HK+L D G V + EP +KL+ QGM+L+ ++      + R     +LV+ ++
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSR----GALVATDK  587

Query  596  DEKGRIIKATDPEGRELVHSGMTKMSKSKNNGIDPQEMVEKYGADTVRLFMMFASPAEMT  655
             EK R     + E  E ++ + +KMSKS +N ++P+++VE+YGADT+R++ MF +P + +
Sbjct  588  VEK-RDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  656  LEWQESGVEGAKRFLGRVWNLVYQYQQNPAKTSLDITALSAEQKVLRREVHKTIAKVSDD  715
            + W E G+EG+++FL+RV  L+         T+ +IT    +   L +  + T+  V+++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLI---------TTKEITE--ENSGALDKVYNETVKAVTEQ  695

Query  716  IGRRQTFNTAIAAVMELMNKLTKASLDSEQDRAVMAEALSAVVRMLYPITPHICFELWQA  775
            +++ + FNTAIA +M ++N        ++++  + ++   + V+++ P++PH+  ELWQA
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  776  L-GNESAIDTAEWVKADEAAMVEDEKLIVVQVNGKVRGKVTVAADADEDTVKTIAFADEN  834
            L ++  +I    W   DE+ +VE++  IVVQ++GKV++K+ VA D   + ++ +A+A+E+
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  835  VKKFIDNQHIVKVIYVVGKLLNVVVK  860
            V+  I  ++I+KVI V  KL+N+V+K
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVIK  833

1263) leuS in NC_022356


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  537 bits (2027),  Expect = 1e-153, Method: Compositional matrix adjust.
 Identities = 361/868 (42%), Positives = 559/868 (65%), Gaps = 50/868 (5%)

Query  5    YRPDMIEPKVQQYWAENKVFKAIKDESKEKYYCLSMFPYPSGR-LHMGHVRNYTIGDVIS  63
            Y    IEPK Q +WA+N  FK+  D SK K+Y L MFPYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPFGWDAFGLPAEGAAIKNKTAPAKWTYENIACMKKQLQLLGFGFDWDR  123
            R++R  G NVL+P GWDAFGLPAE  A+     PA  T ENIA  K+Q++ LGF++DWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EIATCKPEYYKWEQWFFTELYKKGLVYKKNSTVNWCPNDETVLANEQV-HEGCCWRCDTP  182
            E+ T  P+YYKW QW+FT LY KGL Y  +  VNW  +  T +ANE+V  +G   R + P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VEQKEIPQWFIKITDYAEQLLGGLDTLPQWPDMVKTMQRNWIGRSEGVEITFDVADTNEK  242
            V +K + QW +KIT YAE+LL +L+ + +WP+ +K MQRNWIG+S G ++TF V DT+  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  VAVYTTRPDTFYGVSY--LGIaaahplaslaaQNNPELATFIQEAK-NAKVAEADLATME  299
             +V+TTRPDT++G +Y  L+   A   A  ++++   +A + ++A  ++ +A +DLA  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGMATGLFAVHPLTGEKLPIWAANFVLMHYGTGAVMAVPAHDQRDFEFAQKYGLQIKQV  359
            K G+ TG +A++P+ G  +P+W A++VL  YGTGA+MAVPAHD+RD EFA+++ L+I  V
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  360  IEPIADEEIDLTKQAFVEHGKLVNSAEFDGLDFEGAFNGIADKLEKLGVGKRQVNYRLRD  419
            +E    EE      AF E+G  +NS  +DGLD  +A+  + + LE  GVG+ +V YRLRD
Sbjct  362  LEGGNVEE-----AAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMLTLENGDVVPAPIEDLPIILP--EDVVMDGV-KSPIKADPNWAKT  476
            W  SRQRYWG PIP++  E+G   + P  +LP++LP   D+   G   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  TF-NGVPALKETDTFDTFMESSWYYARYTCPQYQNGMLDAEEANYWLPVDQYIGGIEHAT  535
            T  +GV + +ET+T      SSWYY RY  P+  + + D E  + WLPVD Y+GG EHA 
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLLYFRFFHKLLRDAGFVTSDEPADKLLCQGMVLADAFYYTSPTNERIWVSPTQVTLER  595
            +HLLY RF HK+L D G V + EP +KL+ QGM+L+ ++      + R     + V+ ++
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSR----GALVATDK  587

Query  596  DEK--GRIIKATAPEGRELVHSGMTKMSKSKNNGIDPQEMVEKYGADTVRLFMMFASPAE  653
             EK  G ++   +  G EL ++  +KMSKS +N ++P+++VE+YGADT+R++ MF +P +
Sbjct  588  VEKRDGSFFHVET--GEELEQAP-AKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLD  644

Query  654  MTLEWQESGVEGAKRFLGRVWNLVYQYQQNPAKTSLDLTALSAEQKVLRREVHKTIAKVS  713
             ++ W E G+EG+++FL+RV  L+         T+ ++T    +   L +  + T+  V+
Sbjct  645  ASIAWSEEGLEGSRKFLDRVYRLI---------TTKEITE--ENSGALDKVYNETVKAVT  693

Query  714  DDIGRRQTFNTAIAAVMELMNKLTKASLESDQDRAVMAEALSAVVRMLYPITPHICFELW  773
            +++++ + FNTAIA +M ++N        ++++  + ++   + V+++ P++PH+  ELW
Sbjct  694  EQVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELW  745

Query  774  QAL-GNESAIDTAEWVKADEDAMVEDEKLIVVQVNGKVRGKVTVAADADEETVKTIAFAD  832
            QAL ++  +I    W   DE  +VE++  IVVQ++GKV++K+ VA D   E ++ +A+A+
Sbjct  746  QALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALAN  805

Query  833  ENVKKFVDNQHIVKVIYVAGKLLNVVVK  860
            E+V+  +  ++I+KVI V+ KL+N+V+K
Sbjct  806  EKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

1264) leuS in NC_008816


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  537 bits (2028),  Expect = 1e-153, Method: Compositional matrix adjust.
 Identities = 353/858 (42%), Positives = 559/858 (66%), Gaps = 41/858 (4%)

Query  13   NLYNPSEIEKKWQSIWTENNLYKTDELTENSDKFYALSMFPYPSG-NLHMGHVRNYVITD  71
             +Y+ + IE KWQ++W++N+ +KT+    +  KFYAL MFPYPSG  LH+GH   Y  TD
Sbjct  2    TFYDHTAIEPKWQAFWADNHTFKTGT-DASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  72   LIARFQRFKGKSVLHPMGWDAFGLPAENAAIERGISPSVWTKKNISHMKSQLKLLGLSVD  131
            +++RF+R +G +VLHPMGWDAFGLPAE+ A++ G  P+  T  NI++ K Q++ LG+S D
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  132  WDREFATCDENYYIWTQYLFLELYKSGLVYQKESEVNWDPIDNTVLANEQVDSEGKSWRS  191
            WDRE  T D NYY WTQ +F  LY  GL Y+ E  VNW     T +ANE+V ++G S R+
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  192  GAVVEKKLLKQWFLRITNYAdellkdlekldNWPERVKIMQDNWIGKSIGANINFNINTN  251
            G  V +K ++QW L+IT YA E L +     +WPE +K MQ NWIGKS GAN+ F+++ +
Sbjct  181  GYPVVRKPMRQWMLKITAYA-ERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVK-D  238

Query  252  PEKNITVFTTRPDTLFGVTYLAISVNHSLIKKITDQETIQDIENLKQ--YLKDN-KNNEL  308
             +K++TVFTTRPDTLFG TY  ++ +H+L+  IT  +  + + + K+   LK +    +L
Sbjct  239  TDKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDL  298

Query  309  --EKIGIKTSLIAINPVNSEPIPIWVASYVLDEYGTGAVMGVPAHDLRDFEFAKKNNIDI  366
              EK G+ T+  AINPVN+  +P+W+A YVL  YGTGA+M+VPAHD RD EFAK+ N+DI
Sbjct  299  AKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDI  358

Query  367  KQVIVKDKSEQSNELDNAYVENGYLINSNHYNGLANTIAKLKIAE----EGVNNGWAENK  422
              V+  ++ E++     A+ E+G  INS+  +GL ++ A  K+ E    EGV N    ++
Sbjct  359  IPVLEGGNVEEA-----AFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGN----EN  409

Query  423  IQYRLRDWLISRQRYWGCPIPIVNCKKCGAVPLNQSDLPVSLP--KDIEISANKINALGN  480
            + YRLRDWL+SRQRYWG PIPI++     + ++ +S+LP+ LP  KDI  S+   ++L+N
Sbjct  410  VTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLAN  469

Query  481  NNDWINTTCPKCGIGARKETDTMDTFMCSSWYFLRYPSSKCSTKPFEKNEINKWLPVDQY  540
              DW++ T    G+ +R+ET+TM     SSWY+LRY  +  + K  + + +++WLPVD Y
Sbjct  470  VTDWLEVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIY  528

Query  541  VGGVEHAILHLLYARFFTKALRDNELFDIDEPFKKLLTQGMVQSAAYKNNKTGKYVSPSD  600
            VGG EHA+LHLLYARF  K L D  +    EPF+KL+ QGM+ +++Y++++ G  V+   
Sbjct  529  VGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSR-GALVATDK  587

Query  601  ITDLSNPTDPIDNS-KLEVLFEKMSKSKYNGIDPESVIKKYGADTARMFILFKAPPEKDL  659
            +     +   ++ +  LE    KMSKS  N ++P+ V+ +YGADT R++ +F +P +  +
Sbjct  588  VEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASI  647

Query  660  EWGDTDVEGQFRFLSRIWKLYINCAKNINSKSNSHPDKEKSLIKSMNIAIKEISNDILNN  719
             W++ ++EG  +FL R+ +L    +K+I   +++      +L K  N ++K +++++ + 
Sbjct  648  AWSEEGLEGSRKFLDRVYRL--ITTKEITEENSG------ALDKVYNETVKAVTEQVDQM  699

Query  720  QFNTAISELMKFYnslsnsindinnnlkidALKTFCILLAPFAPHIAEEIWH-LIGFKKS  778
            +FNTAI++LM F N+ ++  + +++       K F  L+APFAPH++EE+W+ L +   S
Sbjct  700  KFNTAIAQLMVFVNAANKEDKLFSDYA-----KGFVQLIAPFAPHLGEELWQALTASGES  754

Query  779  VHLEHWPSFNAEALKEDSYELVIQVNGKVRDKVNINNDMSEDQIKELTLKRPNILKWTQD  838
            +    WPS++   L E+  E+V+Q++GKV+ K+ + +D+S ++++E++L   ++     +
Sbjct  755  ISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAG  814

Query  839  KEIRKIIIVKGKIMNIVV  856
            K+I K+I V  K++NIV+
Sbjct  815  KDIIKVIAVPNKLVNIVI  832

1265) leuS in NC_010334


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  537 bits (2027),  Expect = 1e-153, Method: Compositional matrix adjust.
 Identities = 358/866 (42%), Positives = 551/866 (64%), Gaps = 47/866 (5%)

Query  14   YTPSEIEAKVQQHWQDTKTFEVTEDANKEKFYCLSMFPYPSGR-LHMGHVRNYTIGDVVS  72
            Y  + IE+K Q  W D  TF    DA+K KFY L MFPYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  73   RYQRLQGKNVLQPIGWDSFGLPAENAAIKNSTAPAPWTYENIDYMKNQLKMLGFGYDWSR  132
            R++R QG NVL+P+GWD+FGLPAE+ A+  +  PA  T ENI   K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  133  EIATCTPEYYRWEQWFFTKLYEKGLVYKKTSSVNWCPNDETVLANEQVI-DGCCWRCDTT  191
            E+ T  P+YY+W QW+FTKLYEKGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  192  VEQKEIPQWFIKITEYAeellndldqldeWPEQVKTMQRNWIGRSEGIEMTFQVADSDQS  251
            V +K + QW +KIT YA E L +  +  +WPE +K MQRNWIG+S G ++TF+V D+D+ 
Sbjct  184  VVRKPMRQWMLKITAYA-ERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  252  FDIYTTRPDTVMGVTYVAIAAGHPLAEQAAINNP--ALAEFIEECKNADtteaamaamek  309
            F ++TTRPDT+ G TY  +A+ H+L +  + ++   A+A++  +         +  A EK
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEK  302

Query  310  kGVATGLNAIHPITGKEVPIWVGNFVLMNYGTGAVMSVPAHDQRDYEFAKKYSLNIEAVV  369
             GV TG  AI+P+ GKE+P+W++++VL +YGTGA+M+VPAHD+RD EFAK+++L+I +V+
Sbjct  303  TGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL  362

Query  370  KPADGEVDISEEAYTEKGVLFNSAEFDGLDFQAAFDAIDAKLTAEGKGKRQVNFRLRDWG  429
              +    ++ E A+TE G+ +NS  +DGLD  +A+  +   L AEG G+ +V +RLRDW 
Sbjct  363  EGG----NVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWL  418

Query  430  VSRQRYWGAPIPMVTLADGTVIPTPEDQLPVILP--EDVVMDGI-QSPIKSDKEWAKTT-  485
             SRQRYWG PIP++   DGT  + PE +LP++LP   D+   G  +SP+ +  +W   T 
Sbjct  419  FSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTR  478

Query  486  VNGQEAFRETDTFDTFMESSWYYARYCSPHADQML-DPAKANYWLPVDQYIGGIEHACMH  544
             +G  + RET+T      SSWYY RY  PH  + L D    + WLPVD Y+GG EHA +H
Sbjct  479  EDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLH  538

Query  545  LLYFRFFHKLLRDSGLVNSDEPAKRLLTQGMVLADAYYYNNEKGARVWVAPSDVTVLETD  604
            LLY RF HK+L D G+V + EP ++L+ QGM+L+ +Y     +++R     + +   +  
Sbjct  539  LLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSR-----GALVATDKV  588

Query  605  DKGRTVKAVDSEGNELVYTGMSKMSKSKNNGIDPQEMVDKYGADTVRLFMMFAAPPELTL  664
            +K R     + E  E +  + +KMSKS +N ++P+++V++YGADT+R++ MF +P + ++
Sbjct  589  EK-RDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASI  647

Query  665  EWQESSVEGAHRFIKRLWK-TAHDHIATGPTAELDVKSLNAAQKELRRELHKTIAKVGDD  723
             W E ++EG+++F+ R+ +  +  +I+   ++ LD            +  + T+  V ++
Sbjct  648  AWSEEGLEGSRKFLDRVYRLITTKEITEENSGALD------------KVYNETVKAVTEQ  695

Query  724  IERRQMFNTAIASVMELMNRLQKAPSETEQDKALMQEALNAVVRLLYPIIPHTCFVLWND  783
            +++ + FNTAIA +M ++N        ++++  L  +  ++ V+L+ P+ PH    LW+ 
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  784  LGNQG-AIEDVLWPEVDESALVEDSKLIIVQVNGKLRAKITVAADASKEEVETAGMAEEG  842
            L   G +I  V WP  DES LVE+   I+VQ++GK++AK+ VA D S+EE++  ++A+E 
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  843  VVKHTEGKTVRKVIYVPGKLLNIVAN  868
            V  +  GK + KVI VP KL+NIV +
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVIK  833

1266) leuS in NC_007481


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  537 bits (2027),  Expect = 1e-153, Method: Compositional matrix adjust.
 Identities = 352/870 (41%), Positives = 550/870 (64%), Gaps = 52/870 (5%)

Query  5    YNPQKIESKIQRYWEENKVFKVTEDESKEKYYCLSMFPYPSGR-LHMGHVRNYTIGDVVS  63
            Y+   IE+K Q +W +N  FK   D SK K+Y L MFPYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RFQRLKGKNVMQPMGWDAFGLPAENAAIKNKTAPAKWTYENIDYMRTQLKQLGFGYDWDR  123
            RF+R +G NV++PMGWDAFGLPAE+ A+     PA  T ENI   + Q++ LGF+YDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EIATCHPEYYKWEQWFFTKLYEKGLVYKKMSTVNWDPVDQTVLANEQVI-DGRGWRSGAV  182
            E+ T +P+YYKW QW+FTKLYEKGL Y     VNW     T +ANE+V+ DG + R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VEQKEIPQWFIKITDYAQellddldkledWPEQVKTMQRNWIGRSEGCDIEFKRTDNNET  242
            V +K + QW +KIT YA+  L +     DWPE +K MQRNWIG+S G ++ FK  D +  
Sbjct  184  VVRKPMRQWMLKITAYAE-RLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  FSVYTTRPDTFMGVTYVAVAAGHPIAKEAAKNSDSVALFVEECKNNKVSEADMA----TM  298
            F+V+TTRPDT+ G TY  +A+ H++    + + ++ A  V + K +    +D+A    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEA--VADYKRQASLKSDLARTDLAK  300

Query  299  EKKGIATGFFATHPLTGEQVPIWIANFVLMHYGSGAVMAVPAHDQRDFEFATAYGLDIKQ  358
            EK G+ TG +A +P+ G ++P+WIA++VL  YG+GA+MAVPAHD+RD EFA  + LDI  
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VIAPVTGSDLEVNLNKEAFTDKGVLVNSGEFDGLDFDAAFNAIADKLEALGVGERKVNFR  418
            V+          N++  AFT+ G+ +NS+ +DGLD  +A+  + + LEA GVG+ +V +R
Sbjct  361  VLE-------GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYR  413

Query  419  LRDWGVSRQRYWGSPIPMLSDEDGNELAATDDMLPVRLP--EDVVMNGVT-SPIKADPNW  475
            LRDW  SRQRYWG PIP++  EDG   A  +  LP+ LP   D+  +G   SP+    +W
Sbjct  414  LRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDW  473

Query  476  AKTTM-NGAPAFHETDTFDTFMESSWYYARYCSPRHDEGMLDPAAANYWLPVNQYIGGIE  534
               T  +G  + +ET+T      SSWYY RY  P++ E + D    + WLPV+ Y+GG E
Sbjct  474  LEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAE  533

Query  535  HAILHLLYSRFFHKLLRDFGLVDSDEPFDRLLCQGMVLAETFYRKDEKGADIWISPSDVN  594
            HA+LHLLY+RF HK+L D+G+V + EPF++L+ QGM+L+ ++  +D +GA +        
Sbjct  534  HAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY--RDSRGALV--------  583

Query  595  TETDDKGRVTKAWHKVDGNPVFssgmskmsksknngIDPQHVIAQYGADTVRLFMMFTAP  654
              TD   +   +   V+    +  + +KMSKS +N ++P++V+ QYGADT+R++ MF +P
Sbjct  584  -ATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGP  642

Query  655  PEQTLEWSDAGVEGAHRFLKRVWKYAVDVKTVGFQPLNKTALNNEQK-VLRRDLHKAIAK  713
             + ++ WS+ G+EG+++FL RV           ++ +    + +E+   L +  + ++  
Sbjct  643  LDASIAWSEEGLEGSRKFLDRV-----------YRLITTKEITEENSGALDKVYNETVKA  691

Query  714  VSDDVERRQTFNTAIAAIMELSNKLLKAPLNSKQDVAIANEALEAMLIMLAPITPHLSHQ  773
            V+++V++ + FNTAIA +M + N        ++++  + ++   + + ++AP++PHL+++
Sbjct  692  VTEQVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEE  743

Query  774  LWQELGKEGDIVN-ASWPEVDQSALVEDEKLIIIQVNGKLRAKLTVAADATKEQVEALAF  832
            LWQ L   G+ ++  +WP  D+S LVE++  I++Q++GK++AKL VA D ++E+++ +A+
Sbjct  744  LWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVAL  803

Query  833  EQASVTKYTDGVTVRKVIYVPGKLLNVVAN  862
             +  V     G  + KVI VP KL+N+V +
Sbjct  804  ANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

1267) leuS in NC_007109


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  537 bits (2027),  Expect = 1e-153, Method: Compositional matrix adjust.
 Identities = 339/845 (41%), Positives = 556/845 (66%), Gaps = 30/845 (3%)

Query  2    NQIEQKWQQIWYDEKAFEVSNESSKPKYYVLEMLPYPSGK-IHVGHVRNYSIGDVIARFM  60
              IE KWQ +W D+ +F  + ++SKPK+Y L+M+PYPSG  +HVGH   Y+  D+++RF 
Sbjct  7    TAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSRFK  66

Query  61   TMQGFNVLHPMGWDAFGLPAENAAIKNNSHPKDWTYSNIENMKKQLKSMGFSYDWSREIN  120
              QG NVLHPMGWDAFGLPAE+ A+   ++P + T  NI N K+Q++++GFSYDW RE+N
Sbjct  67   RAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDREVN  126

Query  121  SCDPQYYKHEQKFFLELYERNLAYQKESLVNW-DPVDNTVLANEQVVDGRGWRSGAIVEK  179
            + DP+YYK  Q +F  LYE+ LAY+ E  VNW + ++ ++  +E + DG + R+G  V +
Sbjct  127  TTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVR  186

Query  180  RYLKQWFLKITDYAEELLNEIQNLKEWPEAVRSMQEKWIGKSIGANFHFKIKDNEDNTIE  239
            + ++QW LKIT YAE LL++++++ +WPE+++ MQ +WIGKS GAN  FK+KD + + + 
Sbjct  187  KPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD-FT  244

Query  240  VFSTKPETIFGAGFIGIAFNHPIIEKLIS--KTPEILSFITKCSHIT--GSSELEKTEKE  295
            VF+T+P+T+FGA +  +A +H++++ + +  ++  +  +  + S  +  + ++L K EK 
Sbjct  245  VFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK-EKT  303

Query  296  GVFTGLYVIHPFDSNIVLPVIITNFVLMDYGTGAVFGCPAHDERDHELAVKMNLPIKQVI  355
            GV TG Y I+P +++  +PV I+++VL  YGTGA+ + PAHDERD E+A + NL I  V+
Sbjct  304  GVWTGSYAINPVNGK-EMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL  362

Query  356  ETDIDVQKTAYTEDGILVNSDFLNGLTSNEAKQKVIDEFEKLGIGKRSVYYRLKDWGISR  415
            E + +V+ +A+TEDG+ +NSDFL+GL    A  K+++ +E  G+G+ +V YRL+DW +SR
Sbjct  363  EGG-NVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSR  421

Query  416  QRFWGCPIPMIHCEACGIVPVPCSDLPVTLP--DDVSFDGHGN-PLDHHPSWKHVNCPKC  472
            QR+WG PIP+IH E     +VP S+LP+ LP   D+   G G+ PL +   W +V     
Sbjct  422  QRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDG  481

Query  473  DKSAIRETDTFDTFFESSWYFTRYCNSNATE-MTDKKACDYWLPVDKYIGGIEHAVMHLL  531
             K+  RET+T      SSWY+ RY +++ TE ++D      WLPVD Y+GG EHAV+HLL
Sbjct  482  VKGR-RETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  532  YARFFTKVMNEQNYVSVREPFKGLFTQGMVLHATYKDEHNNWLYPEEVVKKGNEFFHKES  591
            YARF  KV+ +   V+ +EPF+ LF QGM+L ++Y+D +   +  + V K++  FFH E+
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET  600

Query  592  NNRVVQGRIEKMSKSKKNLIDLVTMQEQYGADAIRLFVLSDSPPEKDLEWSASGIEGCSR  651
             + + Q+   KMSKS KN+++   + EQYGAD++R++ +  +P +  + WS  G+EG  +
Sbjct  601  GEELEQAP-AKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRK  659

Query  652  FINKLEHMFEAIASLIDDVNSEINKELNRLVHFTIKHVADDIKHFVLNRAIARMRELSNA  711
            F   L++++  I++   ++  E +  L+++ + T+K V++++ +  +N AIA++  + NA
Sbjct  660  F---LDRVYRLITT--KEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNA  714

Query  712  ISAELNKEVVDVKTVRYGFNVIVQLLNPFIPHITEEIWQKL-GNKERLYNSAFPAFDESM  770
             + E +K   D     Y+ + +VQL+ PF PH+ EE+WQ L ++ E +   + P++DES 
Sbjct  715  ANKE-DKLFSD-----YA-KGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESK  767

Query  771  LELDTYVMAVQVNGKLRDTYEFKTSASEDEIKQITVNLPKVQKFLEGKEPKKIILVPRKI  830
            L  +   + VQ++GK++         S +E++++++   KVQ  + GK+  K+I VP K+
Sbjct  768  LVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKL  827

Query  831  VNIIV  835
            VNI++
Sbjct  828  VNIVI  832

1268) leuS in NC_006840


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  537 bits (2025),  Expect = 2e-153, Method: Compositional matrix adjust.
 Identities = 378/867 (44%), Positives = 564/867 (66%), Gaps = 50/867 (5%)

Query  5    YNPQDLEQKIQKHWDDNKTFVVTEDANKEKFYCLSMFPYPSGR-LHMGHVRNYTIGDVVS  63
            Y+   +E K Q  W DN TF    DA+K KFY L MFPYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRLQGKNVMQPIGWDAFGLPAENAAVKNKTAPAPWTYENIEYMKNQLKLLGFGYDWNR  123
            R++R QG NV++P+GWDAFGLPAE+ A+     PA  T ENI   K Q++ LGF+YDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EFATCTPEYYRWEQEFFTKLYNKGLVYKKTSSVNWCPNDQTVLANEQV-EDGCCWRCDTP  182
            E  T  P+YY+W Q +FTKLY+KGL Y    +VNW  +  T +ANE+V  DG   R + P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VEQKKIPQWFIKITEYAQELLDDLDNLDGWPEMVKTMQRNWIGRSEGVELSFAVNGETSP  242
            V +K + QW +KIT YA+ LL+DL+++D WPE +K MQRNWIG+S G +++F V++    
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LEVYTTRPDTLMGVTYVGIAAGHPLAE--KASQNNPELAAFV-EECRNTKVAEAELATME  299
            + V+TTRPDTL G TY  +A+ H+L +   +S++   +A +  +   ++ +A ++LA  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGMDTGLRAIHPLNGREVPVFVANFVLMDYGTGAVMAVPAHDQRDFEFATKYGLDIIPV  359
            K G+ TG  AI+P+NG+E+PV +A++VL  YGTGA+MAVPAHD+RD EFA ++ LDIIPV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  360  IKPEDGSDLDVSEAAYTEKGVLFDSGEFDGLAFQEAFDaiaakleaegkgkkTVNFRLRD  419
            +   +G++++  EAA+TE G+ ++S+ +DGL    A+  +   LEAEG G+  V +RLRD
Sbjct  362  L---EGGNVE--EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMVTTEDGEVHPVPADQLPVILP--EDVVMDGVT-SPIKADKEWAKT  476
            W  SRQRYWG PIP++  EDG   +VP  +LP++LP   D+   G   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  TF-NGEPALRETDTFDTFMESSWYYARYCSPQADDIL-DPEKANYWLPVDQYIGGIEHAC  534
            T  +G  + RET+T      SSWYY RY  P+  + L D E  + WLPVD Y+GG EHA 
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  535  MHLLYSRFFHKLLRDAGYVTSDEPFKQLLCQGMVLADAFYYTNDKGGKEWVAPTDVTIER  594
            +HLLY+RF HK+L D G V + EPF++L+ QGM+L+ +  Y + +G+   + +TD    R
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS--YRDSRGA---LVATDKVEKR  591

Query  595  DGK-GRIEKAIDDQGREVEHSGMIKMSKSKNNGIDPQEMVDKYGADTVRLFMMFASPADM  653
            DG   ++E      G E+E++   KMSKS +N ++P+++V++YGADT+R++ MF +P D 
Sbjct  592  DGSFFHVET-----GEELEQAP-AKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  654  TLEWQESGVEGANRFLKRVWKLVHEHTNKGTTEALDTSSLTGDQKALRRDVHKTIAKVSD  713
            ++ W E G+EG+ +FL RV +L+   T K  TE         +  AL +  + T+  V++
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLI---TTKEITEE--------NSGALDKVYNETVKAVTE  694

Query  714  DIGRRQTFNTAIAAIMELMNKLNKAPQESAQDRALLDEALKAVVAMLYPMTPHASFAMWE  773
            ++++ + FNTAIA +M ++N  NK       +  L+ +  K+ V ++ P +PH +  +W+
Sbjct  695  QVDQMK-FNTAIAQLMVFVNAANK-------EDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  774  ALGESD--LDSATWPTFDENALVEDEKTIVVMINGKLRAKLVVAADATEEHVRELGLKDE  831
            AL  S+  +    WP++DE+ LVE++  IVV I+GK++AKLVVA D + E+++E++L +E
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  832  NAMKFLDGLTIRKVIYVPGKLLNIVAN  858
            +    + G  I KVI VP KL+NIV +
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVIK  833

1269) leuS in NC_010067


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  537 bits (2025),  Expect = 2e-153, Method: Compositional matrix adjust.
 Identities = 360/866 (42%), Positives = 550/866 (64%), Gaps = 48/866 (5%)

Query  5    YRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIA  63
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDSK  182
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADELLSDLDKLDHWPDTVKTMQRNWIGRSEGVEITFDVKGYDNT  242
            V RK + QW +KITAYA+ LL DL+ +D WP+++K MQRNWIG+S G ++TF VK+ D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGATYLAVAAGHPLAQKAAANNPELAVFIDECRNTKVAEAEMA----TM  298
            +TV+TTRPDT+ GATY  +A+ H+L +  ++++   AV   + +      +++A    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAV--ADYKRQASLKSDLARTDLAK  300

Query  299  EKKGVDTGFKAIHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFATKYGLTIKP  358
            EK GV TG  AI+P+ G E+PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L I P
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VILAADGSAPDLSTQALTEKGVLFNSGEFDGLAFEAAFNAIADKLAAKGVGERKVNYRLR  418
            V+      + ++   A+TE G+ +NS+ +DGL   +A+  + + L A GVG+ +V YRLR
Sbjct  361  VL-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  419  DWGVSRQRYWGAPIPMVTLEDGTVIPTPEDQLPVILP--EDVVMDGIT-SPIKADPAWAK  475
            DW  SRQRYWG PIP++  EDGT  + PE +LP++LP   D+   G   SP+     W  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  476  TT-VNGTPAMRETDTFDTFMESSWYYARYTCPQYQEGMLDSKAANYWLPVDIYIGGIEHA  534
             T  +G  + RET+T      SSWYY RY  P+  E + D    + WLPVDIY+GG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  535  IMHLLYFRFFHKLMRDAGMVTSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVE  594
            ++HLLY RF HK++ D G+V + EP ++L+ QGM+L+ ++      + R  + + D +  
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEK  590

Query  595  RDEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADM  654
            RD  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D 
Sbjct  591  RD--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  655  TLEWQESGVEGANRFIKRVWKLVYEHTAKGSVAALNVDTLNDDQKALRRDVHKTIAKVTD  714
            ++ W E G+EG+ +F+ RV +L+   T+K        +  +++  AL +  + T+  VT+
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLI---TTK--------EITEENSGALDKVYNETVKAVTE  694

Query  715  DIGRRQTFNTAIAAIMELMNKLAKAPQDSEQDRALMQEALLAVVRMLNPFTPHVCFTLWQ  774
            ++++ + FNTAIA +M ++N        ++++  L  +   + V+++ PF+PH+   LWQ
Sbjct  695  QVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  775  ALEGEGD-IDNAPWPVADDKAMVEESTLIVVQVNGKVRGKITVPVNATEEQVRERAGQEH  833
            AL + G+ I   PWP  D+  +VE+   IVVQ++GKV++K+ V+ + + E+++E A  ++
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  834  LVAKYLDGVTVRKVIYVPGKLLNLVV  859
             V   + G  + KVI VP KL+N+V+
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVI  832

1270) Dacet_1236 in NC_013943


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  537 bits (2028),  Expect = 9e-154, Method: Compositional matrix adjust.
 Identities = 355/858 (42%), Positives = 551/858 (65%), Gaps = 38/858 (4%)

Query  3    YNPAGIETKWQKIWEDEKLFKVEKDDTKEKFYCLEMFPYPSGK-IHMGHVRNYAIGDVIS  61
            Y+ ++IE KWQ +W D+  FK   D +K KFY L+MFPYPSG  +H+GH   Y+  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  62   RYKFMQGLNVLHPIGWDAFGLPAENAAIENSTHPAVWTKQNISYMKQQLKKLGLAYDWDR  121
            R+K  QG NVLHP+GWDAFGLPAE+ A++ + +PA  T +NI+  K+Q++ LG++YDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  122  EIATCDPEYYKWEQKIFIEMWEKGLIYKKKSHLNWCDDCNTVLANEQV-EDGACWRCGNE  180
            E+ T DP+YYKW Q IF  + EKGL Y     +NW ++  T +ANE+V  DG+  R G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  181  VAIKELDGWYLKITDYADELLEYTDKLPGWPSKVLTMQSNWIGKSYGAkidfkikdiddk  240
            V  K +  W LKIT YA+ LLE  + + +WP  +  MQ NWIGKS GA++ FK+KD D  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  241  iTVFTTRPDTLFGATFMSVAPEHPIVKTLLAGTEKEKDGLAFIDSILKDDKISRMDDDKE  300
            +TVFTTRPDTLFGAT+  +APEH++V ++ ++ + E  +    ++ LK D ++R D  KE
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSD-LARTDLAKE  301

Query  301  KRGFFTGRYVLNPVTGIDMPIYIANFVLMDYGTGAVMAVPAHDQRDFEFAKKYGCDLRIV  360
            K G  TG Y +NPV G +MP+ IA++VL  YGTGA+MAVPAHD+RD EFAK++  D+  V
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  361  IQPKEELSLETMTEAYSGAGKLVNSGQFDGIPNEDAKKMIIDWLDDQNIGESTINYRLRD  420
            ++       +    A++  G  +NS+ +DG+ +  A   +++WL+ + +G+  + YRLRD
Sbjct  362  LEGG-----NVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  421  WQISRQRYWGAPIPFISCDKCGTVPVPMDQLPVKLPDV-NFNPDMRGN-PLDKVESFKNT  478
            W +SRQRYWG PIP+I  +   + +VP  +LP+ LP   ++ P   G+ PL +V    + 
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  479  TCPKCGGAAVRETDTMDTFMESSWYFMRYTSPDCDTAPFDKDQANYWMNVDQYIGGIEHA  538
            T    G  + RET+TM     SSWY++RY  P+      D +  + W+ VD Y+GG EHA
Sbjct  477  TRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  539  ILHLLYARFYTKVLRDLGYINIDEPFKRLLTQGMVCKETYKCPDHGWLFPEDSTDGKCSK  598
            +LHLLYARF  KVL DLG +   EPF++L+ QGM+   +Y+ +  + L + D  + + + 
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGA-LVATDKVEKRDGS  594

Query  599  -----CGKDVTVGRVEKMSKSKKNVVDPNKLIQEYGADTARLFILFASPPERELEWSDTA  653
                  G ++  +   KMSKS KNVV+P+ ++++YGADT R++ +F +P +  + WS+ +
Sbjct  595  FFHVETGEELEQAPA-KMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEG  653

Query  654  VEGSFRFINRVWRLIQNNVNLFKEELPTSTEDDITKEILFHTNVTVKKVTEDIERYQLNT  713
            +EGS +F++RV RLI  +      E+     + + K  +++   TVK VTE++++ ++NT
Sbjct  654  LEGSRKFLDRVYRLITTK------EITEENSGALDK--VYNE--TVKAVTEQVDQMKFNT  703

Query  714  CVAAMMEFVNNLYAIEPKIQDGHKTHFKDAILTLMKLMAPFTPHAAEELYE-MTGLPGHI  772
             +A +M FVN          + +   F D    +++L+APF+PH +EEL + +T+    I
Sbjct  704  AIAQLMVFVNA--------ANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESI  755

Query  773  SRSDWPSFDEKLTQKDEITVAVQVNGKLRGQIDIPRNMGKDEVFVTAKQNENVQKHIEGL  832
            S   WPS+DE     +++ + VQ++GK+++++ ++++++++E+   A  NE+VQ +I G 
Sbjct  756  SYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGK  815

Query  833  NMIKEIYVPNKLVNFVVK  850
            ++IK I VPNKLVN+V+K
Sbjct  816  DIIKVIAVPNKLVNIVIK  833

1271) leuS in NC_018692


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  536 bits (2024),  Expect = 2e-153, Method: Compositional matrix adjust.
 Identities = 364/873 (42%), Positives = 558/873 (64%), Gaps = 54/873 (6%)

Query  6    YNPKDIEQRVQQYWEENQSFKANDDVEKEKFYCLSMFPYPSGR-LHMGHVRNYTIGDVIS  64
            Y+   IE + Q +W +N++FK+  D  K KFY L MFPYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  65   RFQRMQGKNVLQPMGWDAFGLPAENAAINNNTAPAKWTYSNIDYMKNQLRSLGFGYDWDR  124
            RF+R QG NVL+PMGWDAFGLPAE+ A++    PA  T  NI   K Q+ +LGF+YDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  125  EVTTCKSDYYRWEQWFFTRLYEKGLVYKKNSTVNWDPVDQTVLANEQVI-DGRGWRSGAL  183
            EV T  ++YY+W QW+FT+LYEKGL Y  +  VNW     T +ANE+V+ DG + R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  184  VEQKEIPQWFIKITDYAeellqdleqleeWPDQVRAMQANWIGRSEGVEITFDLASAVND  243
            V +K + QW +KIT YA E L +  +  +WP+ ++ MQ NWIG+S G ++TF +  + + 
Sbjct  184  VVRKPMRQWMLKITAYA-ERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDK-  241

Query  244  IADLTVYTTRPDTFYGVTYVAVAAQHPLAEFAAKSNPDLAAFIDECKNTKVAEAELA---  300
              D+TV+TTRPDT++G TY  +A++H+L +  A + +D A  + + K      ++LA   
Sbjct  242  --DFTVFTTRPDTLFGATYAVLAPEHALVD--AITTSDQAEAVADYKRQASLKSDLARTD  297

Query  301  -TMEKKGFATGFEVVHPLTGEKLPIWVANFVLMDYGSGAVMAVPGHDQRDWEFATKYNLP  359
             + EK G  TG   ++P+ G  +P+W+A++VL  YG+GA+MAVP+HD+RDWEFA ++NL 
Sbjct  298  LAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLD  357

Query  360  IKQVIAPNAGDEDKCDLTASAFTEKGSLINSDKFDGLEFDAAFNGIADELEGKGCGKRKV  419
            I  V+     +E       +AFTE G  INSD +DGL+  +A+  + + LE+ G G+ +V
Sbjct  358  IIPVLEGGNVEE-------AAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENV  410

Query  420  NYRLRDWGVSRQRYWGAPIPMLNLENGESVPVPADQLPVVLP--EDVEMNGVT-SPIKAD  476
             YRLRDW  SRQRYWG PIP+++ E+G S +VP  +LP+VLP   D+  +G   SP+   
Sbjct  411  TYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANV  470

Query  477  PEWAKITY-NGQAALRETDTFDTFMEsswyyaryasaaNNDAMLDPTSANYWLPVDQYIG  535
             +W  +T  +G  + RET+T      SSWYY RY  + N + + D    + WLPVD Y+G
Sbjct  471  TDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVG  530

Query  536  GIEHAILHLLYSRFFHKLLRDEGLVNSDEPFKRLLCQGMVLADSYYREDASGKKTWFSPT  595
            G EHA+LHLLY+RF HK+L D G+V + EPF++L+ QGM+L+ S YR+  ++        
Sbjct  531  GAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS-YRDSRGAL-------  582

Query  596  EVSTEKDEKGRIVKAWLTADGEEVIHGGMTKMSKSKNNGIDPQEVIDQYGADTVRLFTMF  655
             V+T+K EK     + +  +  E ++ + +KMSKS +N ++P++V++QYGADT+R++ MF
Sbjct  583  -VATDKVEKRD--GSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMF  639

Query  656  AAPPEQTLEWVDSGVEGANRFLRRIWKLVTEHVEKGTPEAIDVNALSKDQQALRREVHKT  715
             +P + ++ W + G+EG+ +FL R+ +L+T    K   E         +  AL +  + T
Sbjct  640  MGPLDASIAWSEEGLEGSRKFLDRVYRLIT---TKEITEE--------NSGALDKVYNET  688

Query  716  IEKVSDDLGRRQTFNTAVAAVMELLNHLQKAPQDNAQDIAIMREACESILLLLNPITPHI  775
            +  V++++++ + FNTA+A +M ++N  +K  +       +  +   +++ L+ P++PH+
Sbjct  689  VKAVTEQVDQMK-FNTAIAQLMVFVNAANKEDK-------LFSDYAKGFVQLIAPFAPHL  740

Query  776  AHELWKVL-GHNEDIDLAPWPQADKAALVEDEKLIIVQVNGKVRAKMTIAADASKESIEA  834
            ++ELW+ L +  E I   PWP  D + LVE++  I+VQ++GKV+AK+ +A D S+E ++ 
Sbjct  741  GEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQE  800

Query  835  SAKEQPNVQQFIEGKTIRKVIVVPGKLVNIVAN  867
             A  + +VQ  I GK I KVI VP KLVNIV +
Sbjct  801  VALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

1272) leuS in NC_007712


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  536 bits (2024),  Expect = 2e-153, Method: Compositional matrix adjust.
 Identities = 356/866 (42%), Positives = 557/866 (65%), Gaps = 46/866 (5%)

Query  4    LYRPEEIESTVQQHWHENDTFKVTEDPCKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVI  62
            +Y    IE+  Q  W +N+TFK   D+ K K+Y L M+PYPSG  LH+GH   YT  D++
Sbjct  3    FYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDIL  62

Query  63   ARYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYANIDYMKNQLKLLGFGYDWS  122
            +R++R  G NVL+P+GWDAFGLPAE  A+     PA  T  NI   K Q++ LGF+YDW 
Sbjct  63   SRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWD  122

Query  123  REVTTCRPDYYRWEQWFFTRLYEKGLVYKKTSAVNWCPQDQTVLANEQVI-DGCCWRCDT  181
            REV T  P+YY+W QW+FT+LYEKGL Y    +VNW  +  T +ANE+V+ DG   R + 
Sbjct  123  REVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGY  182

Query  182  KVERKEIPQWFVKITAYADQLLYDLDKLESWPEQVKTMQRNWIGRSEGVEITFQVADSEE  241
             V RK + QW +KITAYA++LL DL+ ++ WPE +K MQRNWIG+S G ++TF+V D++ 
Sbjct  183  PVVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDK  241

Query  242  TLTVYTTRPDTFMGTTYVAVAAGHPL--SLQAAASNPALADFIQECR-TTKVAEADMATM  298
             +TV+TTRPDT+ G+TY  +A+ H+L  ++ ++    A+AD+ ++    + +A +D+A  
Sbjct  242  DFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-K  300

Query  299  EKKGMATGLHAVHPLTGEMLPVWVANFVLMDYGTGAVMAVPGHDQRDFEFARKYDLPVKP  358
            EK G+ TG  A++P+ G  +PVW+A++VL  YGTGA+MAVP+HD+RD EFA++++L + P
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VIRNADGSEPDLSAQAMTEKGVLFNSGEFDGLDFQAGFNAIADALVAQGVGERKVNYRLR  418
            V+  ++  E+     A TE G+ +NS+ +DGLD  +++  + + L A+GVG+ +V YRLR
Sbjct  361  VLEGGNVEEA-----AFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  419  DWGVSRQRYWGAPIPMMTLEDGTVVPTPEDQLPVVLP--EDVVMDGIS-SPLKADPDWAK  475
            DW  SRQRYWG PIP++  EDGT  + PE +LP+VLP   D+   G + SPL    DW  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  476  TT-YNGQPALRETDTFDTFMESSWYYARYTCPDYDRGMLDPAAANYWLPVDQYIGGIEHA  534
             T  +G  + RET+T      SSWYY RY  P+    + D    + WLPVD Y+GG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  535  IMHLMYFRFYHKLLRDAGLVTSDEPAKRLLCQGMVLADAFYYLTSSGERVWVSPLEVSVE  594
            ++HL+Y RF HK+L D G+V + EP ++L+ QGM+L+ ++      + R   ++L V+ +
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSR---GAL-VATD  586

Query  595  RDEKGRIVKSTDASGRELVYAGMSKMSKSKNNGIDPQEMVEKYGADTVRLFMMFASPAEM  654
            + EK         +G EL   + +KMSKS +N ++P+++VE+YGADT+R++ MF +P + 
Sbjct  587  KVEKRDGSFFHVETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  655  TLEWQESGVEGANRFLKRVWKLAYEHPQQGPVGALDIDALNDEQKALRREVHKTIAKVTD  714
            ++ W E G+EG+ +FL RV +L         + + +I   +++  AL +  + T+  VT+
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRL---------ITTKEIT--EENSGALDKVYNETVKAVTE  694

Query  715  DIGRRQTFNTAIAAIMELMNKLARAPQQTGQDRALLQEALVAVVRMLYPFTPHACFTLWR  774
            ++++ + FNTAIA +M ++N        + ++  L+ +   + V+++ PF+PH    LW+
Sbjct  695  QVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  775  ALGGEGD-IDNAPWPVADEAAMVEDAKLVVIQVNGKLRGRITVPADADEALVCERASQEH  833
            AL + G+ I   PWP  DE+ +VE+   +V+Q++GK+++++ V+ D     + E A  ++
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  834  LVAKHLEGTTVRKVIYVPGKLLNLVV  859
             V  ++ G  + KVI VP KL+N+V+
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVI  832

1273) AciX9_2117 in NC_015064


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  536 bits (2024),  Expect = 2e-153, Method: Compositional matrix adjust.
 Identities = 351/865 (41%), Positives = 533/865 (62%), Gaps = 73/865 (8%)

Query  29   YTPAEIEPKWQARWDADPSLYAADAHDSGKPKYYCLEMLPYPSGA-LHIGHVRNYAIGDA  87
            Y  + IEPKWQA W  + ++    + D++KPK+Y L+M+PYPSGA LH+GH   Y+  D 
Sbjct  4    YDHTAIEPKWQAFWADNHTF--KTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDI  61

Query  88   LARFMWMRGHNVLHPMGWDAFGLPAENAALKNNVPPREWTLSNIASMKKQFQRLGMGFDW  147
            L+RF + +GHNVLHPMGWDAFGLPAE+ A+     P E T  NIA+ K+Q++ LG ++DW
Sbjct  62   LSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDW  121

Query  148  SKEVTTCLPDYYRWNQWLFLKMFERGLAYRKKSKVNWCPQCATVLANEQVIQGRCWRHDE  207
             +EV T  P+YY+W QW+F K++E+GLAY     VNW  + +T +ANE+V+ +    ++ 
Sbjct  122  DREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGG  181

Query  208  TVVEQRDLTQWFLRITKYADELLTGLDKLEGWPEKVRTMQRNWIGRSEGTNVDFMVANAP  267
              V ++ + QW L+IT YA+ LL +L+ ++ WPE ++ MQRNWIG+S G+NV F V ++ 
Sbjct  182  YPVVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDT-  239

Query  268  ASASNGSKITVFTTRVDTIFGATSIQLAPEHAVAKAFAAEDPRlaeeiealllqqqkaRE  327
                 +  +TVFTTR DT+FGAT   LAPEHA+  A+++ D   A          +    
Sbjct  240  -----DKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLA  294

Query  328  TDELGAIEKHGVPTGRFAVNPFNGERVPIWVANYILADYGTGAIMSVPAHDERDFEFATK  387
              +L+  EK GV TG +A+NP NG  +P+W+A+Y+LA YGTGAIM+VPAHDERD EFA +
Sbjct  295  RTDLAK-EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQ  353

Query  388  YNLPIKRVIAPNLDTDDLPLPYLAEEEAVLIDSGEWSGEACLEAQDKMAAFVETGSFGSK  447
            +NL I  V+    + ++ ++     E+++ I+S+   G     A  KM   +E+ + G+ 
Sbjct  354  FNLDIIPVLEGG-NVEEAAFT----EDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNE  408

Query  448  TVTYRLKDWGVSRQRYWGTPIPMVYCEACGADEPIPVPESQLPILLP--EQIAITQEGGS  505
             VTYRL+DW  SRQRYWG PIP++  E   +    +VPES+LP++LP   +I  +  G S
Sbjct  409  NVTYRLRDWLFSRQRYWGEPIPIIHWEDGTS---TAVPESELPLVLPVTKDIRPSGTGES  465

Query  506  PLGRVPEFVNTTCPKCGGPARRETDTMDTFVDSSWYFYRYTDPHNDTAPFDSAKVNYWFP  565
            PL+ V + ++ T    G  +RRET+TM    +SSWY+ RY DPHN     D   ++ W+P
Sbjct  466  PLANVTDWLEVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLP  524

Query  566  IDQYIGGVEHAILHLIYSRFWTKVMRDLGLIVNDEPAERLFTQGMVI-------------  612
            +D Y+GG EHA+LHL+Y+RFW KV+ DLG++   EP ++LF QGM++             
Sbjct  525  VDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVA  584

Query  613  ------KDG---------------AKMSKSKGNVVSPDLMIDRYGADATRMYALFAAPPD  651
                  +DG               AKMSKS  NVV+PD ++++YGAD+ R+Y +F +P D
Sbjct  585  TDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLD  644

Query  652  RDLDWQEEGVAGISRFLGKIFRLTTKFAQLEGGEAGPADAALLRKLHQTIAKVTHDFSGR  711
              + W EEG+ G  +FL++++RL T        E    +++ L K+ +   K   +  ++
Sbjct  645  ASIAWSEEGLEGSRKFLDRVYRLIT------TKEITEENSGALDKVYNETVKAVTEQVDQ  698

Query  712  WHFNTSISSIMILVNEITANEAAIDAGQVTAATVKSTLRSLIQMIAPFAPFLAAELWETL  771
              FNT+I+ +M++VN    ++  +              ++++Q+IAPFAP L+ ELW++L
Sbjct  699  MKFNTAIAQLMVFVNAANKEDKLFS----------DYAKGFVQLIAPFAPHLGEELWQAL  748

Query  772  GEQGIVFRH-PWPESDAALAREDEISIPVQVNGKLANVIKLPSESTDEEVKAAALLDEKV  830
               G  +   PWP  D +   E+++ I VQ++GK+   + ++ + + EE++  AL +EKV
Sbjct  749  TASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKV  808

Query  831  AARIAGKTIVKVVYVPGKLVNLVVK  855
             A IAGK I+KV+ VP KLVN+V+K
Sbjct  809  QAEIAGKDIIKVIAVPNKLVNIVIK  833

1274) leuS in NC_014306


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  536 bits (2023),  Expect = 2e-153, Method: Compositional matrix adjust.
 Identities = 354/865 (41%), Positives = 551/865 (64%), Gaps = 46/865 (5%)

Query  5    YRPEEIESHVQQHWDEKQTFKVTEEEGKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIS  63
            Y    IE+  Q  W +++TFK   + +K K+Y L M+PYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKLLGFGYDWNR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q++ LGF+YDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCQPEYYRWEQWFFTKLYEKGLVYKKTSAVNWCPTDQTVLANEQVI-DGCCWRCDTK  182
            E+ T +P+YY+W QW+FTKLYEKGL Y    +VNW     T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFVKITDYADELLNDLDTLESWPEQVKTMQRNWIGRSEGVEITFDVAESPEK  242
            V RK + QW +KIT YA+ LL+DL+ ++ WPE +K MQRNWIG+S G ++TF V ++   
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LSVYTTRPDTFMGVTY--LavaaghplaaqaaasnpalaDFIAECR-NTKVAEAEMATME  299
            ++V+TTRPDT+ G TY  LA   +   A  ++    A+AD+  +   ++ +A +++A  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGMATGKFAVHPLSGEKVPVWVANFVLMEYGTGAVMAVPGHDQRDWEFATKYNLTIKPV  359
            K G+ TG +A++P++G  +PVW+A++VL  YGTGA+MAVP+HD+RDWEFA ++NL I PV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  360  ILNADGSEPDLTDAAMTDKGTLFNSGEFDGLSYEAGFNAIAEKLAAKGVGERKVNYRLRD  419
            +  ++  E+ +T+ ++  ++ +     +DGL   +++  + E L A GVG+ +V YRLRD
Sbjct  362  LEGGNVEEAAFTEDGLHINSDF-----LDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMVTLEDGTVMPTPEDQLPVILP--EDVVMDGIT-SPIKADPEWAKT  476
            W  SRQRYWG PIP++  EDGT  + PE +LP++LP   D+   G   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  T-VNGQPALRETDTFDTFMESSWYYARYTCPDYDKGMLDPAAANYWLPVDQYVGGIEHAI  535
            T  +G  + RET+T      SSWYY RY  P+    + D    + WLPVD YVGG EHA+
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLLYFRFFHKLLRDAGLVTSNEPAKRLLCQGMVLADAFYYLGASGERNWVSPVDVTLER  595
            +HLLY RF HK+L D G+V ++EP ++L+ QGM+L+ +  Y ++ G         V+ ++
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS--YRDSRGAL-------VATDK  587

Query  596  DEKGRVTKATDATGRELVYAGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPAEMT  655
             EK   +     TG EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P + +
Sbjct  588  VEKRDGSFFHVETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  656  LEWQESGVEGANRFLKRVWRLAFEHSEKGPTVALDIASLNDDQKSLRRELHKTIAKVSDD  715
            + W E G+EG+ +FL RV RL           + +I+  +++  +L +  + T+  V+++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRL---------ITTKEIT--EENSGALDKVYNETVKAVTEQ  695

Query  716  IGRRQTFNTAIAAIMELMNKLARAPQESEQDRALMQEALQSVVRLLYPFTPHACFSLWQA  775
            +++ + FNTAIA +M ++N        ++++  L  +  ++ V+L+ PF+PH    LWQA
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  776  LGGEGD-VDNAPWPQADEEAMVEDSLLVVVQVNGKVRGKITVPADATAEQVKARALQEHL  834
            L + G+ +   PWP  DE  +VE+ + +VVQ++GKV++K+ V+ D + E+++  AL ++ 
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  835  VAKYVDGTTIRKEIYVPGKLLNLVV  859
            V   + G  I K I VP KL+N+V+
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVI  832

1275) leuS in NC_011184


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  536 bits (2023),  Expect = 3e-153, Method: Compositional matrix adjust.
 Identities = 377/867 (44%), Positives = 564/867 (66%), Gaps = 50/867 (5%)

Query  5    YNPQDLEQKIQKHWDDNKTFVVTEDANKEKFYCLSMFPYPSGR-LHMGHVRNYTIGDVVS  63
            Y+   +E K Q  W DN TF    DA+K KFY L MFPYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRLQGKNVMQPIGWDAFGLPAENAAVKNKTAPAPWTYENIEYMKNQLKLLGFGYDWNR  123
            R++R QG NV++P+GWDAFGLPAE+ A+     PA  T ENI   K Q++ LGF+YDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EFATCTPEYYRWEQEFFTKLYSKGLVYKKTSSVNWCPNDQTVLANEQV-EDGCCWRCDTP  182
            E  T  P+YY+W Q +FTKLY KGL Y    +VNW  +  T +ANE+V  DG   R + P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VEQKKIPQWFIKITEYAQELLDDLDNLDGWPEMVKTMQRNWIGRSEGVELSFAVNGEESP  242
            V +K + QW +KIT YA+ LL+DL+++D WPE +K MQRNWIG+S G +++F V++ +  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LEVYTTRPDTLMGVTYVGIAAGHPLAE--KASQNNPELAAFV-EECRNTKVAEAELATME  299
            + V+TTRPDTL G TY  +A+ H+L +   +S++   +A +  +   ++ +A ++LA  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGMDTGLRAIHPLNGREVPVFVANFVLMDYGTGAVMAVPAHDQRDFEFATKYGLDIIPV  359
            K G+ TG  AI+P+NG+E+PV +A++VL  YGTGA+MAVPAHD+RD EFA ++ LDIIPV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  360  IKPEDGSDLDVSEAAYTEKGVLFDSGEFDGLAFQEAFDaiaakleaegkgkkTVNFRLRD  419
            +   +G++++  EAA+TE G+ ++S+ +DGL    A+  +   LEAEG G+  V +RLRD
Sbjct  362  L---EGGNVE--EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMVTTEDGEVHPVPADQLPVILP--EDVVMDGVT-SPIKADKEWAKT  476
            W  SRQRYWG PIP++  EDG   +VP  +LP++LP   D+   G   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  TF-NGEPALRETDTFDTFMESSWYYARYCSPQADDIL-DPEKANYWLPVDQYIGGIEHAC  534
            T  +G  + RET+T      SSWYY RY  P+  + L D E  + WLPVD Y+GG EHA 
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  535  MHLLYSRFFHKLLRDAGYVTSDEPFKQLLCQGMVLADAFYYTNDKGGKEWVAPTDVTIER  594
            +HLLY+RF HK+L D G V + EPF++L+ QGM+L+ +  Y + +G+   + +TD    R
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS--YRDSRGA---LVATDKVEKR  591

Query  595  DAK-GRIEKAVDDQGREVEHSGMIKMSKSKNNGIDPQEMVDKYGADTVRLFMMFASPADM  653
            D+   ++E      G E+E++   KMSKS +N ++P+++V++YGADT+R++ MF +P D 
Sbjct  592  DGSFFHVET-----GEELEQAP-AKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  654  TLEWQESGVEGANRFLKRVWKLVHEHTNKGTTEALDTSSLTGDQKALRRDVHKTIAKVSD  713
            ++ W E G+EG+ +FL RV +L+   T K  TE         +  AL +  + T+  V++
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLI---TTKEITEE--------NSGALDKVYNETVKAVTE  694

Query  714  DIGRRQTFNTAIAAIMELMNKLNKAPQESAQDRALLDEALKAVVAMLYPMTPHASFAMWE  773
            ++++ + FNTAIA +M ++N  NK       +  L+ +  K+ V ++ P +PH +  +W+
Sbjct  695  QVDQMK-FNTAIAQLMVFVNAANK-------EDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  774  ALGESD--LDSATWPTFDENALVEDEKTIVVMINGKLRAKLVVAADATEEHVRELGLKDE  831
            AL  S+  +    WP++DE+ LVE++  IVV I+GK++AKLVVA D + E+++E++L +E
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  832  NAMKFLDGLTIRKVIYVPGKLLNIVAN  858
            +    + G  I KVI VP KL+NIV +
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVIK  833

1276) leuS in NC_011753


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  536 bits (2021),  Expect = 3e-153, Method: Compositional matrix adjust.
 Identities = 372/868 (43%), Positives = 558/868 (65%), Gaps = 52/868 (5%)

Query  5    YNPQEIEQKVQQHWDDSETFVVSEDPNKEKFYCLSMFPYPSGR-LHMGHVRNYTIGDVVS  63
            Y+   IE K Q  W D++TF  + D++K KFY L MFPYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RFQRLQGKNVMQPIGWDAFGLPAENAAVKNNTAPAPWTYENIEYMKNQLKLLGFGYDWKR  123
            RF+R QG NV++P+GWDAFGLPAE+ A+     PA  T ENI   K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EFATCTPEYYRWEQEFFTKLYEQGLVYKKTSSVNWCPNDQTVLANEQV-EDGCCWRCDTP  182
            E  T  P+YY+W Q +FTKLYE+GL Y    +VNW  +  T +ANE+V  DG   R + P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VEQKKIPQWFIKITEYAQELLDDLDNLEGWPEMVKTMQRNWIGRSEGVELSFAVNGEEAP  242
            V +K + QW +KIT YA+ LL+DL++++ WPE +K MQRNWIG+S G +++F V++ +  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LEVYTTRPDTLMGVSYVGIAAGHPLAEKASKNNPELAAFVEECRNTKVAEAELA----TM  298
            + V+TTRPDTL G +Y  +A+ H+L +  + ++   A  V + +      ++LA    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEA--VADYKRQASLKSDLARTDLAK  300

Query  299  EKKGMDTGLTAIHPLNGRVVPVYVANFVLMDYGTGAVMAVPAHDQRDYEFATKYGIDIIP  358
            EK G+ TG  AI+P+NG+ +PV +A++VL  YGTGA+MAVPAHD+RD EFA ++ +DIIP
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VIKPEDGSELDVSEAAYTEKGVLFDSGEFDGLAFQEAFDaiaakleaegkgkkTVNFRLR  418
            V+        +V EAA+TE G+ ++S+ +DGL    A+  +   LEAEG G+  V +RLR
Sbjct  361  VLEGG-----NVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  419  DWGVSRQRYWGAPIPMVTTEDGEVHPVPADQLPVILP--EDVVMDGVT-SPIKADKSWAE  475
            DW  SRQRYWG PIP++  EDG   +VP  +LP++LP   D+   G   SP+     W E
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  476  TTF-NGEPALRETDTFDTFMESSWYYARYCSPQADDIL-DPEKANYWLPVDQYVGGIEHA  533
             T  +G  + RET+T      SSWYY RY  P+  + L D E  + WLPVD YVGG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  534  CMHLLYSRFFHKLLRDAGYVTSDEPFKQLLCQGMVLADAFYHENEKGTKEWIAPTDVTVE  593
             +HLLY+RF HK+L D G V + EPF++L+ QGM+L+ ++   + +G+   + +TD    
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY--RDSRGA---LVATDKVEK  590

Query  594  RDGK-GRIEKAVDDQGREVEHSGMIKMSKSKNNGIDPQEMVDKYGADTVRLFMMFASPAD  652
            RDG   ++E      G E+E++   KMSKS +N ++P+++V++YGADT+R++ MF +P D
Sbjct  591  RDGSFFHVET-----GEELEQAP-AKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLD  644

Query  653  MTLEWQESGVEGANRFLKRVWKLVHAHSSKGAAETVDASALSGNQKALRRDIHKTIAKVT  712
             ++ W E G+EG+ +FL RV +L+   ++K  +E         N  AL +  + T+  VT
Sbjct  645  ASIAWSEEGLEGSRKFLDRVYRLI---TTKEITE--------ENSGALDKVYNETVKAVT  693

Query  713  DDIGRRQTFNTAIAAIMELMNKLAKAPQESVQDRAILDEALKAVVRMLYPMTPHISYEMW  772
            +++++ + FNTAIA +M ++N   K       +  ++ +  K+ V+++ P +PH++ E+W
Sbjct  694  EQVDQMK-FNTAIAQLMVFVNAANK-------EDKLFSDYAKGFVQLIAPFAPHLGEELW  745

Query  773  IALGES--NVDSATWPTFDEKALVEDEKTIVVMINGKLRAKLTVAADATEEQVRELGLND  830
             AL  S  ++    WP++DE  LVE++  IVV I+GK++AKL VA D + E+++E++L +
Sbjct  746  QALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALAN  805

Query  831  ENAKKFLDGLTIRKVIFVPGKLLNIVAN  858
            E+ +  + G  I KVI VP KL+NIV +
Sbjct  806  EKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

1277) leuS in NC_011886


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  536 bits (2022),  Expect = 3e-153, Method: Compositional matrix adjust.
 Identities = 357/853 (42%), Positives = 543/853 (64%), Gaps = 62/853 (7%)

Query  24   YSFAAMEARWPQVWEDLKVFTPADDGSRERRYVLDMFPYPSG-DLHMGHAEAFAMGDVVA  82
            Y  +A+E++W   W D   F  + D+S+ + Y LDMFPYPSG +LH+GH+E+++  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  83   RYLRQQGFDVLHPIGWDSFGLPAENAAIKRNAHPSEWTYTNIDTQAASFKRYAISADWSR  142
            R+ R QG +VLHP+GWD+FGLPAE+ A+    +P+E T  NI      ++  ++S DW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  143  RLHTSDPEYYRWTQWLFKRFYERGLAYRKNSPVNWCPKDQTVLANEQVV-NGACERCGTV  201
             ++T+DP+YY+WTQW+F ++YE+GLAY  + PVNW     T +ANE+V+ +G+ ER G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  202  VTKKSLNQWYFKITDYADRLLDDMEQLRGHWPERVLAMQKNWIGRSEGAHVNFVIEADGG  261
            V +K++ QW +KIT YA+RLL+D+E++  +WPE +  MQ+NWIG+S GA+V F +     
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV--DWPESIKDMQRNWIGKSTGANVTFKVKD---  238

Query  262  KPAKDVTVFTTRPDTLYGATFFVVAADAPIAVELVTDEHAAALDEYRETVKALSEIERQS  321
               KD TVFTTRPDTL+GAT+ V+A++ ++   + T ++A A+ +Y+      S++ R  
Sbjct  239  -TDKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTD  297

Query  322  TEREKTGVFTGRYAINPLNGEKLPVWAADYVLADYGTGAIMAVPAHDQRDLDFAKTFDLP  381
              +EKTGV TG YAINP+NG  +PVW ADYVLA YGTGAIMAVPAHD+RD +FAK F+L 
Sbjct  298  LAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLD  357

Query  382  VRAVLDtgeedpaatgtatagegtLINSGELDGLPKaeaipaaiaiLERQGTGEKFVNFR  441
            + +VL+ G+ + AA           INS+ LDGL KA AI+  +  LE +G G+  V +R
Sbjct  358  IIPVLEGGNVEEAAFTEDGLH----INSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYR  413

Query  442  LRDWLLSRQRFWGTPIPIIHCPSCGEVPVPDEQLPVTLPSDLRGEDLAPKGTSPLAAAED  501
            LRDWL+SRQR+WG PIPIIH       +VP+ +LP+ LP   ++   +  G SPLA   D
Sbjct  414  LRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVT-KDIRPSGTGESPLANVTD  472

Query  502  WVNVECPNCHGAAKRDTDTMDTFVDSSWYFLRFVSPDYTEGPFDPAKINDWMPVGQYVGG  561
            W++V   +    ++R+T+TM    +SSWY+LR++ P+ TE   D   +++W+PV+ YVGG
Sbjct  473  WLEVTREDG-VKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGG  531

Query  562  VEHAILHLLYARFFTKVINDLGLIEASEPFSALLNQGQVLNGG-----------------  604
             EHA+LHLLYARF  KV+ DLG++ + EPF  L+NQG +L  +                 
Sbjct  532  AEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKR  591

Query  605  -----------------KAMSKSLGNGVDLGEQLDKYGVDAVRLTMVFASPPEDDVDWAD  647
                               MSKSL N V+ ++ +++YG D++R+  +F +P +  + W++
Sbjct  592  DGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSE  651

Query  648  VSPSGSAKFLARAWRLAQDVTSSPGTEASAGDRGLRSVTHRTIADAAELLDANKFNVVVA  707
             +  GS KFL R  RL   +T+   TE ++G  +L  V + T+   +E +D  KFN  +A
Sbjct  652  EGLEGSRKFLDRVYRL---ITTKEITEENSG--ALDKVYNETVKAVTEQVDQMKFNTAIA  706

Query  708  KLMELVNATRKAIDSGAGGADPavreaaeavavILSLFAPYTAEDMWNVLGHPA-SVANA  766
            +LM +VNA+ K         D    + A +   +++ FAP  +E++W+ L  ++ S++  
Sbjct  707  QLMVFVNAANK--------EDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYV  758

Query  767  GWPAHDPSLLvqdtvtavvqvqGKVRDRLEISPDISEDSLRELALASENVQRALDGRGIR  826
             WP+ D S LV++ V  VVQ++GKV+ +L ++ D+S + L+E+ALA+E+VQ  + G++I 
Sbjct  759  PWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDII  818

Query  827  TVIVRAPKLVNIV  839
             VI  + KLVNIV
Sbjct  819  KVIAVPNKLVNIV  831

1278) leuS in NC_007146


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  536 bits (2022),  Expect = 3e-153, Method: Compositional matrix adjust.
 Identities = 359/866 (42%), Positives = 557/866 (65%), Gaps = 46/866 (5%)

Query  5    YRPDMIEPKVQQYWAENKVFKAIKDESKEKYYCLSMFPYPSGR-LHMGHVRNYTIGDVIS  63
            Y    IEPK Q +WA+N  FK+  D SK K+Y L MFPYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPFGWDAFGLPAEGAAIKNKTAPAKWTYENIAYMKKQLQLLGFGFDWDR  123
            R++R  G NVL+P GWDAFGLPAE  A+     PA  T ENIA  K+Q++ LGF++DWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EIATCKPEYYKWEQWFFTELYKKGLVYKKTSTVNWCPNDETVLANEQV-HEGCCWRCDTP  182
            E+ T  P+YYKW QW+FT LY KGL Y     VNW  +  T +ANE+V  +G   R + P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VEQKEIPQWFIKITDYAEQLLGGLDALPQWPDMVKTMQRNWIGRSEGVEITFDVANTNEK  242
            V +K + QW +KIT YAE+LL +L+ + +WP+ +K MQRNWIG+S G ++TF V +T+  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  VAVYTTRPDTFYGVSY--LGIaaahplaslaaQNNSELAAFIQEAK-NAKVAEADLATME  299
             +V+TTRPDT++G +Y  L+   A   A  ++++   +A + ++A  ++ +A +DLA  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGMATGLFAIHPLTGEKLPIWVANFVLMHYGTGAVMAVPAHDQRDFEFAQKYSLQIKQV  359
            K G+ TG +AI+P+ G  +P+W+A++VL  YGTGA+MAVPAHD+RD EFA++++L+I  V
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  360  IEPIADEEIDLTKQAFVEHGKLVNSAEFDGKDFDGAFNGIADKLEKLGVGKRQVNYRLRD  419
            +E    EE      AF E+G  +NS  +DG D  +A+  + + LE  GVG+ +V YRLRD
Sbjct  362  LEGGNVEE-----AAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMLTLENGDVVPAPMEDLPIILP--EDVVMDGV-KNPIKADPNWAKT  476
            W  SRQRYWG PIP++  E+G   + P  +LP++LP   D+   G   +P+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  TL-NGAPALKETDTFDTFMESSWYYARYTCPQYQNGMLDAEEANYWLPVDQYIGGIEHAT  535
            T  +G  + +ET+T      SSWYY RY  P+  + + D E  + WLPVD Y+GG EHA 
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLLYFRFFHKLLRDAGFVTSDEPADKLLCQGMVLADAFYYTSPTNERIWVSPTLVTLER  595
            +HLLY RF HK+L D G V + EP +KL+ QGM+L+ ++      + R     +LV+ ++
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSR----GALVATDK  587

Query  596  DEKGRIIKATDPEGRELVHSGMTKMSKSKNNGIDPQEMVEKYGADTVRLFMMFASPAEMT  655
             EK R     + E  E ++ + +KMSKS +N ++P+++VE+YGADT+R++ MF +P + +
Sbjct  588  VEK-RDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  656  LEWQESGVEGAKRFLGRVWNLVYQYQQNPAKTSLDITALSAEQKVLRREVHKTIAKVSDD  715
            + W E G+EG+++FL+RV  L+         T+ +IT    +   L +  + T+  V+++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLI---------TTKEITE--ENSGALDKVYNETVKAVTEQ  695

Query  716  IGRRQTFNTAIAAVMELMNKLTKASLDSEQDRAVMAEALSAVVRMLYPITPHICFELWQA  775
            +++ + FNTAIA +M ++N        ++++  + ++   + V+++ P++PH+  ELWQA
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  776  L-GNESAIDTAEWVKADEAAMVEDEKLIVVQVNGKVRGKVTVAADADEDTVKTIAFADEN  834
            L ++  +I    W   DE+ +VE++  IVVQ++GKV++K+ VA D   + ++ +A+A+E+
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  835  VKKFIDNQHIVKVIYVVGKLLNVVVK  860
            V+  I  ++I+KVI V  KL+N+V+K
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVIK  833

1279) leuS in NC_010336


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  536 bits (2021),  Expect = 3e-153, Method: Compositional matrix adjust.
 Identities = 351/859 (41%), Positives = 555/859 (65%), Gaps = 72/859 (8%)

Query  1    MSEYNFTQIEQQAQEYWRENNSFKAVEDKNKEKFYCLSMLPYPSGT-LHMGHVRNYTIGD  59
            M+ Y+ T IE + Q +W +N++FK+  D +K KFY L M+PYPSG+ LH+GH   YT  D
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  60   VIARYQKMQGKNVLHPMGWDAFGLPAENAAIKHKKSPYEWTKSNIAYMRSQLDSLGFSFD  119
            +++R+++ QG NVLHPMGWDAFGLPAE+ A+   + P E T  NIA  + Q+++LGFS+D
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  120  WSREVATCDESYYKWEQWFFIQLYKKGLAYRKNSVVNW-DPVDQTVLANEQVVDGRGWRS  178
            W REV T D +YYKW QW+F +LY KGLAY  +  VNW + ++ ++  +E + DG + R+
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  179  GALIEKKEIPQWFLKITDYADELLKDINQLDGWPEAVKTMQTNWIGKSKGLTVKFKIQNS  238
            G  + +K + QW LKIT YA+ LL D++++D WPE++K MQ NWIGKS G  V FK++++
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDT  239

Query  239  DKEIEVFTTRPDTLMGVSYLGIAPEHPLALEEAKTNSQLKSFIDECKRISTMEADLA---  295
            DK++ VFTTRPDTL G +Y  +APEH+L   +A T S+    + + KR +++ +DLA   
Sbjct  240  DKDFTVFTTRPDTLFGATYAVLAPEHALV--DAITTSDQAEAVADYKRQASLKSDLARTD  297

Query  296  -TQEKKGFKTSIQAIHPISGETVNVWVANFVLMGYGSGAVMSVPAHDQRDWEFAQKYNIA  354
             ++EK G  T+  AI+P++G  + VW+A++VL +YG+GA+M+VPAHD+RDWEFA+++N+ 
Sbjct  298  LAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLD  357

Query  355  LKQVIKPSDNKSKLDLDKEAFTEKGILINSGEFDGLNFKSAYQAIKKYLFDNDKGYETTN  414
            +  V+  +      +++  AFTE G+ INS+ +DGL+  SA   +   L  ++ G E   
Sbjct  358  IIPVLEGG------NVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVT  411

Query  415  FRIHDWGISRQRYWGCPIPMIHCNDCGLVPEKEENLPVKLPTNVTLTEAG---SPLKDIP  471
            +R++DW +SRQRYWG PIP+IH +D    +  E +LP+ LP    +  +G   SPL ++ 
Sbjct  412  YRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVT  471

Query  472  EFLNVACPNCGKPATRetdtfdtffessWYYARYTCPTADKMLSEEA--NYWLPVDKYIG  529
            + L+V+  +  K + RET+T      SSWYY RY  P     L++E   + WLPVD Y+G
Sbjct  472  DWLEVTREDGVK-GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVG  530

Query  530  GIEHAIMHLLYARFFHKLMRDQGLVTSDEPFKNLLTQGMVL-------------------  570
            G EHA++HLLYARF HK++ D G+V + EPF++L+ QGM+L                   
Sbjct  531  GAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEK  590

Query  571  KDG---------------AKMSKSKGNTVDPQELIDKYGADTVRLFSMFAAPPEQSLEWS  615
            +DG               AKMSKS  N V+P++++++YGADT+R++ MF +P + S+ WS
Sbjct  591  RDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWS  650

Query  616  DTGVDGANKFLRKVYNYAYTNKEILAKNITIDVTKLSKNDKKARYEIYANLKQAIFDFDK  675
            + G++G+ KFL +VY    T KEI + + +  + K+ ++  KA   +  ++ Q  F+   
Sbjct  651  EEGLEGSRKFLDRVYRLI-TTKEI-TEENSGALDKVYNETVKA---VTEQVDQMKFNTAI  705

Query  676  SQFNTVVSACMKILNTLNNYDNLSDSVKLEGFSILLRILSPFTPHICHYLWQEI-GLGED  734
            +Q+   V+A  K  + +++Y +        GF   +++++PF+PH+ + LWQ + + GE 
Sbjct  706  AQLMVFVNAANKEDKLFSDYAK--------GF---VQLIAPFAPHLGEELWQALTASGES  754

Query  735  ILHTQFPTVDDIALEKDEFLLVVQINGKVKVKLELDASLTKEQVEQEVLSDEQIKTFIKD  794
            I     P+ D+  L  ++  +VVQI+GKVK KL +   L++E++++  L++E++++ I +
Sbjct  755  ISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAG  814

Query  795  KQIVKVIYVPQKLINIVVK  813
            K+I+KVI VP+KL+NIV+K
Sbjct  815  KDIIKVIAVPNKLVNIVIK  833

1280) Thet_0297 in NC_014538


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  535 bits (2020),  Expect = 4e-153, Method: Compositional matrix adjust.
 Identities = 380/849 (45%), Positives = 543/849 (64%), Gaps = 59/849 (6%)

Query  5    VDVDRKWQKKWEETKLYKFNPKNVDKKLYCLEMFSYPSGAKLHVGHWYNYGPTDSWARMK  64
              ++ KWQ  W +   +K        K+Y L+MF+YPSGA LHVGH   Y +TD  +R K
Sbjct  7    TAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSRFK  66

Query  65   RMQGYEVFHPMGFDAFGLPAENYAIKTGIHPYDSTMENIRTMEKQLKEMGATFDWDYEVI  124
            R QG +V+HPMG DAFGLPAE+YA+ TG +P + T ENI    +Q++ +G ++DWD EV 
Sbjct  67   RAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDREVN  126

Query  125  TCLPEYYKWTQWIFLKLFEAGLAYRKKAPVNWCPSCQTVLANEQVI-DGKCERCGTEVTK  183
            T  P+YYKWTQWIF KL+E GLAY    PVNW     T +ANE+V+ DG  ER G  V +
Sbjct  127  TTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVR  186

Query  184  KDLTQWFFKITAYAeellekldeldWPEKTKIMQRNWIGKSDGAEIEFKVAGKDLTFKVF  243
            K + QW +KITAYAE LLE L+E+DWPE  K MQRNWIGKS GA++ FKV + D  F VF
Sbjct  187  KPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVF  246

Query  244  TTRADTLYGATYVVIAPEHEIVDLITTEEYKQAVEEYKEYARKQSEIERLSTEKEKTGVF  303
            TTR+DTL+GATY V+APEH +VD ITT +  +AV +YK  A  +S++ R    KEKTGV 
Sbjct  247  TTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVW  306

Query  304  TGAYAIHPLTGEKLPIWIADYVLATYGTGCVMAVPAHDERDYEFATKYNLPIKRVIKGIG  363
            TG+YAI+P+ G  +P+WIADYVLA+YGTG +MAVPAHDERD EFA ++NL I  V+ G G
Sbjct  307  TGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEG-G  365

Query  364  DIDDSLPFVEYGELVDSGEFTGLKSEEARIKIVEKLKQEGRAEFKVNYRLRDWLVSRQRY  423
            +++++ +F E G  ++S+ + GL    A  K+VE L  EG ++ +V YRLRDWL SRQRY
Sbjct  366  NVEEA-AFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRY  424

Query  424  WGAPIPVIH--CERCGIvpvpeedlpvllpYDVEFAPTGESPLKKHEGFMNVTCPKCGGK  481
            WG PIP+IH        VP +E  L + +  D+  + TGESPL +  + ++VT    G K
Sbjct  425  WGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED-GVK  483

Query  482  ALRDPDTLDTFVDSSWYFLRYPDNKNDKEPFNKEWINKMLPVDKYVGGAEHATMHLLYAR  541
            + R+ +T+    +SSWY+LRY D  N     + E +++ LPVD YVGGAEHA +HLLYAR
Sbjct  484  GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYAR  543

Query  542  FVTKALRDLGYLDFDEPFKSLVHQGTILGP------------------------------  571
            F  K L DLG +   EPF+ L +QG ILG                               
Sbjct  544  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEE  603

Query  572  ---DGSRMSKSKGNVISPDEYIKEYGSDVFRLYLMFGFAYSEGGPWNDDGIKAISRFVNR  628
                 ++MSKS  NV++PD+ + +YG+D +R+Y MF  +   + +W+++G+ +  +F++R
Sbjct  604  LEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR  663

Query  629  VERFIDKFIETKNNPGKTKDEMGKDENELNYVRHYAIKSVTEDAERFQFNTAIARIMELV  688
            V R+I            TK+    +   L+ V + ++K+VTE+ ++ +FNTAIA++M +V
Sbjct  664  VYRLI-----------TTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFV  712

Query  689  NALYKYDTDVEVKNIEFYEDVVADLIRLLAPFAPHFSEEMWEKLGYEYSVFN-QKWPKWD  747
            NA          K+  ++ D   ++++L+APFAPH++EE+W+ L      ++   WP  D
Sbjct  713  NA--------ANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYD  764

Query  748  EKALQRDVVEIAVQVNGKVRGRLEVPSNAPDEEVQRIALSDDKIKSYLDGKEikkvivvk  807
            E  L  + VEI VQ++GKV+++L V+ + + EE+Q +AL+++K+++ + GK+I KVI V 
Sbjct  765  ESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVP  824

Query  808  GRLVNIVVK  816
             +LVNIV+K
Sbjct  825  NKLVNIVIK  833

1281) leuS in NC_010320


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  535 bits (2020),  Expect = 4e-153, Method: Compositional matrix adjust.
 Identities = 380/849 (45%), Positives = 543/849 (64%), Gaps = 59/849 (6%)

Query  5    VDVDRKWQKKWEETKLYKFNPKNVDKKLYCLEMFSYPSGAKLHVGHWYNYGPTDSWARMK  64
              ++ KWQ  W +   +K        K+Y L+MF+YPSGA LHVGH   Y +TD  +R K
Sbjct  7    TAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSRFK  66

Query  65   RMQGYEVFHPMGFDAFGLPAENYAIKTGIHPYDSTMENIRTMEKQLKEMGATFDWDYEVI  124
            R QG +V+HPMG DAFGLPAE+YA+ TG +P + T ENI    +Q++ +G ++DWD EV 
Sbjct  67   RAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDREVN  126

Query  125  TCLPEYYKWTQWIFLKLFEAGLAYRKKAPVNWCPSCQTVLANEQVI-DGKCERCGTEVTK  183
            T  P+YYKWTQWIF KL+E GLAY    PVNW     T +ANE+V+ DG  ER G  V +
Sbjct  127  TTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVR  186

Query  184  KDLTQWFFKITAYAeellekldeldWPEKTKIMQRNWIGKSDGAEIEFKVAGKDLTFKVF  243
            K + QW +KITAYAE LLE L+E+DWPE  K MQRNWIGKS GA++ FKV + D  F VF
Sbjct  187  KPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVF  246

Query  244  TTRADTLYGATYVVIAPEHEIVDLITTEEYKQAVEEYKEYARKQSEIERLSTEKEKTGVF  303
            TTR+DTL+GATY V+APEH +VD ITT +  +AV +YK  A  +S++ R    KEKTGV 
Sbjct  247  TTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVW  306

Query  304  TGAYAIHPLTGEKLPIWIADYVLATYGTGCVMAVPAHDERDYEFATKYNLPIKRVIKGIG  363
            TG+YAI+P+ G  +P+WIADYVLA+YGTG +MAVPAHDERD EFA ++NL I  V+ G G
Sbjct  307  TGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEG-G  365

Query  364  DIDDSLPFVEYGELVDSGEFTGLKSEEARIKIVEKLKQEGRAEFKVNYRLRDWLVSRQRY  423
            +++++ +F E G  ++S+ + GL    A  K+VE L  EG ++ +V YRLRDWL SRQRY
Sbjct  366  NVEEA-AFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRY  424

Query  424  WGAPIPVIH--CERCGIvpvpeedlpvllpYDVEFAPTGESPLKKHEGFMNVTCPKCGGK  481
            WG PIP+IH        VP +E  L + +  D+  + TGESPL +  + ++VT    G K
Sbjct  425  WGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED-GVK  483

Query  482  ALRDPDTLDTFVDSSWYFLRYPDNKNDKEPFNKEWINKMLPVDKYVGGAEHATMHLLYAR  541
            + R+ +T+    +SSWY+LRY D  N     + E +++ LPVD YVGGAEHA +HLLYAR
Sbjct  484  GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYAR  543

Query  542  FVTKALRDLGYLDFDEPFKSLVHQGTILGP------------------------------  571
            F  K L DLG +   EPF+ L +QG ILG                               
Sbjct  544  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEE  603

Query  572  ---DGSRMSKSKGNVISPDEYIKEYGSDVFRLYLMFGFAYSEGGPWNDDGIKAISRFVNR  628
                 ++MSKS  NV++PD+ + +YG+D +R+Y MF  +   + +W+++G+ +  +F++R
Sbjct  604  LEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR  663

Query  629  VERFIDKFIETKNNPGKTKDEMGKDENELNYVRHYAIKSVTEDAERFQFNTAIARIMELV  688
            V R+I            TK+    +   L+ V + ++K+VTE+ ++ +FNTAIA++M +V
Sbjct  664  VYRLI-----------TTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFV  712

Query  689  NALYKYDTDVEVKNIEFYEDVVADLIRLLAPFAPHFSEEMWEKLGYEYSVFN-QKWPKWD  747
            NA          K+  ++ D   ++++L+APFAPH++EE+W+ L      ++   WP  D
Sbjct  713  NA--------ANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYD  764

Query  748  EKALQRDVVEIAVQVNGKVRGRLEVPSNAPDEEVQRIALSDDKIKSYLDGKEikkvivvk  807
            E  L  + VEI VQ++GKV+++L V+ + + EE+Q +AL+++K+++ + GK+I KVI V 
Sbjct  765  ESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVP  824

Query  808  GRLVNIVVK  816
             +LVNIV+K
Sbjct  825  NKLVNIVIK  833

1282) leuS in NC_014974


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  535 bits (2020),  Expect = 4e-153, Method: Compositional matrix adjust.
 Identities = 381/878 (44%), Positives = 551/878 (63%), Gaps = 52/878 (5%)

Query  9    YNPHAIEPKWQRFWKEK-GFMKAKEVPGRKGKQYVLVMFPYPSG-DLHMGHLKNYTMGDV  66
            Y+  AIEPKWQ FW ++  F  + +  + K K Y L MFPYPSG +LH+GH   YT  D+
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTD--ASKPKFYALDMFPYPSGAGLHVGHPEGYTATDI  61

Query  67   LARFRKVQGYEVLHPMGWDAFGLPAENAALKFGLHPRDWTYENIRQAKESLELMGILYDW  126
            L+RF++ QG +VLHPMGWDAFGLPAE+ A+  G +P + T ENI + K  ++ +G+ YDW
Sbjct  62   LSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDW  121

Query  127  DREVTTCEPDYYRFNQWIFLKMWEKGLAYRAKGLVNWCPRCQTVLANEQVVEGRCWRHED  186
            DREV T +P+YY+  QWIF K+ EKGLAY A   VNW     T +ANE+V+ +    + +
Sbjct  122  DREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGG  181

Query  187  TPVEKRELEQWYLRITAYAERLLEDLEGLDWPEKVKAMQRAWIGRSEGAEIEFPVEGLKE  246
             PV ++ + QW L+ITAYAERLLEDLE +DWPE +K MQR WIG+S GA++ F V +   
Sbjct  182  YPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDK  241

Query  247  AITVFTTRPDTLFGATFMVLAPEHPLTLRLASPerraeveayveaaKRKTEIERQAEGRE  306
             +TVFTTRPDTLFGAT+ VLAPEH+L   ++++++   V  Y   A  K+++ R   ++E
Sbjct  242  DFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKE  301

Query  307  KTGVFLGAYAINPATGEKIPIYTADYVLYGYGTGAIMGVPGHDQRDFEFAQKFGLPIRKV  366
            KTGV  G+YAINP  G  +P+  ADYVL +YGTGAIM+VP+HD+RD EFA++F L I  V
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  367  IERpgeplpepleaayeepgIMVNSGPFDGTPSEEGKKKVVAWLEERGLGRAKVTYRLRD  426
            +E       +  EAA+ E G+ +NS+ +DG     +  K+V WLE  G+G  +VTYRLRD
Sbjct  362  LE-----GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  427  WLISRQRYWGTPIPMIHCPRCGVVPVPYEDLPVVLPDLRDIEDIRPKGKSPLEAHPEFYE  486
            WL+SRQRYWG PIP+IH       +VP  +LP+VLP  +DI      G SPL    +  E
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRP-SGTGESPLANVTDWLE  475

Query  487  TTCPKCGGPAKRDTDTMDTFVDSSWYYLRYTDPKNETLPFDPAKADFWMPVDQYIGGVEH  546
             T    G  ++R+T+TM    +SSWYYLRY DP N     D      W+PVD Y+GG EH
Sbjct  476  VTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEH  534

Query  547  AVLHLLYSRFFTKFLHDLGMVKVEEPFQGLFTQGMVLAWTDFGPVEVEGDRLRLPEPTRV  606
            AVLHLLY+RF  K L DLG+V   EPFQ LF QGM+L+ T +      + R  L    +V
Sbjct  535  AVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILG-TSY-----RDSRGALVATDKV  588

Query  607  RLEIPEKELSLEEVRKMGAELRPHEDGTLHFWKPAVMSKSKGNGVMVGPFVKEEGADIAR  666
                          ++ G+ ++ + +  L+   PA MSKS  N V  +  V + GAD  R
Sbjct  589  E-------------KRDGSFFHVETGEELEQ-APAKMSKSLKNVVNPDDVVEQYGADTLR  634

Query  667  ITILFAAPPENEMVWTEEGVQGAWRFLNRIWRRVAEDREALLATSGQFVAESLEGPDREL  726
            +  +F +P +  + W+EEG++G+++FL+R+ R         L T+ ++  E+  + D+ +
Sbjct  635  VYEMFMGPLDASIAWSEEGLEGSRKFLDRVYR---------LITTKEITEENSGALDK-V  684

Query  727  YQKLHATLKKVTEDLEALRFNTAIAALMELLNALYEYRKVRPVTPVYRTAIRYYLQMLFP  786
            Y   + T+K VTE+++ ++FNTAIA LM ++NA            ++    + ++Q++ P
Sbjct  685  Y---NETVKAVTEQVDQMKFNTAIAQLMVFVNA------ANKEDKLFSDYAKGFVQLIAP  735

Query  787  FAPHIAEELWHWF--WPDSLFEAGWPELDEKALEKDVVEVAVQVNGRVRGTIRIPKDAPL  844
            FAPH++EELW+ +    +S+    WP  DE  L  + VE+ VQ++G+V++ + ++KD + 
Sbjct  736  FAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSR  795

Query  845  EVARAEALKVRNVQAHVEGKAIVKEIYVPGKILNLVVR  882
            E  +  AL   +VQA++ GK I+K I VP K++N+V++
Sbjct  796  EELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

1283) Theba_1985 in NC_017934


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  535 bits (2020),  Expect = 4e-153, Method: Compositional matrix adjust.
 Identities = 334/834 (41%), Positives = 522/834 (63%), Gaps = 49/834 (5%)

Query  2    YDFRAIEKKWQEYYAKEKPFNIDLEKAERPFYNLMMFPYPSAAGLHIGNMFSFIGSDVYG  61
            YD  AIE KWQ + A +  F+ + + +   FY L MFPYPS+AGLH+G+  ++ ++D+ +
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  62   RFMKLKGYDVFEPIGFDAFGIHSENYALKVGKHPAELTPKSIEYFREEQLKKIGNIFDWN  121
            RF + +G +V++P+G DAFG+ +E+YA+  G++PAE+T+ +I  F+  Q++ +G  +DW+
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKR-QINALGFSYDWD  122

Query  122  SEAITSSPEYYKWTQWIFIQLFKNGLAEKRSSNVNWCPSCKTVLADEQVI-DGRCERCNS  180
             E  T+ P+YYKWTQWIF +L+ +GLA      VNW     T +A+E+V+ DG  ER   
Sbjct  123  REVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGY  182

Query  181  EVEKREMSQWFFKITEYAEKLLSNLEKLDWTDTTKNLQRAWIGKSSGATISFEVSGMNEK  240
             V ++ M QW +KIT YAE+LL +LE +DW ++ K++QR WIGKS+GA ++F V + +  
Sbjct  183  PVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  241  IDVFTTRPDTIFGVTYIVVAPEYGLVSKLITPSTLQAFENFKEEVKNMDLATRTSISRPK  300
            + VFTTRPDT+FG TY V+APE +LV  + T+   +A  ++K +       +RT +++ K
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEK  302

Query  301  NGIFTGSYAVHPLTGEELPIWIGDYVLAEYGTGAVMAVPAHDERDYVFAKKYGLEIKQVI  360
             G+ TGSYA++P+ G E+P+WI+DYVLA YGTGA+MAVPAHDERD  FAK++ L+I  V+
Sbjct  303  TGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL  362

Query  361  E-CDPSQLPYTEKGKMINSGKYSDMLS-----ADFIERIDEVSESIKGSVNYHLHDWCIS  414
            E  +  + ++TE G  INS+ + D L      A  +E+++  + + + +V Y+L+DW +S
Sbjct  363  EGGNVEEAAFTEDGLHINSD-FLDGLDKASAIAKMVEWLEAEGVG-NENVTYRLRDWLFS  420

Query  415  RQRYWGPPIPIVYCDKCGTIPVPEDQLPVTLPNTDDYIPDGSGKSPLAKNEEFVNTICPV  474
            RQRYWG PIPI+  +   + +VPE +LP+ LP T D  P G+G SPLA+  + ++ +   
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE-VTRE  479

Query  475  CGGPARRETDVSDNFLDSAWYYLRYLSPNDNSAPFDDGLVEKWCPVDMYIGGNEHATLHL  534
             G  +RRET+   +  +S+WYYLRY+ P++     D+ L+ +W PVD+Y+GG EHA LHL
Sbjct  480  DGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHL  539

Query  535  MYSRFLSMALHDMGFLPFEEPFTSFRGHGLII-------------------KDG------  569
            +Y+RF    L D+G +P  EPF  +  +G+I+                   +DG      
Sbjct  540  LYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVE  599

Query  570  ---------EKMSKSKGNIVNPNEYFESHGVDTLRTYLMFMGTFLEGGDFRDSGMDAMRR  620
                      KMSKS  N+VNP++  E  G DTLR Y MFMG +  +    + G+++ R+
Sbjct  600  TGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRK  659

Query  621  FLNRVWDIATMPE--GRSSTELKIKMSETVEKVDYSVKNIKPNTAIAAIMEFVNEASKEV  678
            FL+RV  + T  E    +S  L    +ETV  V   V ++K NTAIA +M FVN A+KE 
Sbjct  660  FLDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKED  719

Query  679  SIERQLVIDMAKLLSPFAPFVCEEIYSMKGGKKKTILDDGFPYGYEKYASMAK-TELPVQ  737
             +  +   +  +L++PFAP + EE+     +   +I     P +Y+    + +  E+ VQ
Sbjct  720  KLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWP-SYDESKLVENDVEIVVQ  778

Query  738  ITGKMRGKVVLPQNASQEEAMEAVMADEKLSKMLEGKSIRKIIYVQDKIINIII  791
            I GK+++K+V++++ S+EE  E  +A+EK+   + GK I K+I V +K++NI+I
Sbjct  779  IKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

1284) leuS in NC_016944


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  535 bits (2018),  Expect = 5e-153, Method: Compositional matrix adjust.
 Identities = 374/867 (44%), Positives = 561/867 (65%), Gaps = 50/867 (5%)

Query  5    YNPQDIEHKVQQHWDNNKTFVVSEDPNKEKFYCLSMFPYPSGR-LHMGHVRNYTIGDVVS  63
            Y+   IE K Q  W +N TF  + D++K KFY L MFPYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RFQRLQGKNVLQPIGWDAFGLPAENAAVKNNTAPAPWTYENIEYMKNQLKLLGFGYDWNR  123
            RF+R QG NVL+P+GWDAFGLPAE+ A+     PA  T ENI   K Q++ LGF+YDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EFATCRPEYYRWEQEFFTKLFAKGLVYKKTSSVNWCPNDQTVLANEQV-EDGCCWRCDTP  182
            E  T  P+YY+W Q +FTKL+ KGL Y    +VNW  +  T +ANE+V  DG   R + P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VEQKEIPQWFIKITAYAQELLDDLDNLDGWPEMVKTMQRNWIGRSEGVELKFAVKGENTD  242
            V +K + QW +KITAYA+ LL+DL+++D WPE +K MQRNWIG+S G ++ F VK+ + D
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LEVYTTRPDTLMGVTYVGIAAGHplatkaaannpalaaFIDECKNTKVAEAEIA----TM  298
            + V+TTRPDTL G TY  +A+ H+L    ++++ A A  + + K      +++A    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEA--VADYKRQASLKSDLARTDLAK  300

Query  299  EKKGMATGLTAIHPLNGREVPIYIANFVLMDYGTGAVMAVPAHDQRDFEFATKYGLDIIP  358
            EK G+ TG  AI+P+NG+E+P+ IA++VL  YGTGA+MAVPAHD+RD EFA ++ LDIIP
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VIKPADGSELDVSEAAYTEKGVLFASGEFDGLDFQAAFNaiaakleaegkgkkTVNFRLR  418
            V+  +     +V EAA+TE G+ + S+ +DGLD  +A+  +   LEAEG G+  V +RLR
Sbjct  361  VLEGG-----NVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  419  DWGVSRQRYWGAPIPMVTTEDGQVHPVPADQLPVILP--EDVVMDGVT-SPIKADKEWAK  475
            DW  SRQRYWG PIP++  EDG   +VP  +LP++LP   D+   G   SP+    +W  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  476  TTF-NGEPALRETDTFDTFMESSWYYARYCSPQADDIL-DPEKANYWLPVDQYIGGIEHA  533
             T  +G  + RET+T      SSWYY RY  P+  + L D E  + WLPVD Y+GG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  534  CMHLLYSRFFHKLLRDAGYVKSDEPFKKLLCQGMVLADAFYYTNDKGGKEWVSPTEVKVE  593
             +HLLY+RF HK+L D G V + EPF+KL+ QGM+L+ +  Y + +G+   + +T+    
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS--YRDSRGA---LVATDKVEK  590

Query  594  RDGKGRIVSAVDATGRQVEHSGMIKMSKSKNNGIDPQEMVDKYGADTVRLFMMFASPADM  653
            RDG    V     TG ++E++   KMSKS +N ++P+++V++YGADT+R++ MF +P D 
Sbjct  591  RDGSFFHV----ETGEELEQAP-AKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  654  TLEWQESGVEGANRFLRRVWKLVREHTELGQAPALDASALNADQKALRRDVHKTIAKVTD  713
            ++ W E G+EG+ +FL RV +L+       + ++           AL +  + T+  VT+
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLITTKEITEENSG-----------ALDKVYNETVKAVTE  694

Query  714  DVARRQTFNTAIAAIMELMNKLTKAPMTEAQDRAILDEALKAITLMLYPITPHICFEMWV  773
            +V + + FNTAIA +M ++N       +  ++  ++ +  K++  ++ P++PH+  E+W 
Sbjct  695  QVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  774  ALGQS--NIDTASWPTYDEAALVEDEKLIVLQVNGKLRGKLTVAADATQQQVEALGMQDE  831
            AL  S  +I   +WP+YDE+ LVE++  IV+Q++GK+++KL VA D ++++++ +++ +E
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  832  NVQKFIDGLTVRKVIYVPGKLLNIVAN  858
            +VQ  I G  + KVI VP KL+NIV +
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVIK  833

1285) VCLMA_A0816 in NC_017270


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  535 bits (2018),  Expect = 5e-153, Method: Compositional matrix adjust.
 Identities = 374/867 (44%), Positives = 561/867 (65%), Gaps = 50/867 (5%)

Query  5    YNPQDIEHKVQQHWDNNKTFVVSEDPNKEKFYCLSMFPYPSGR-LHMGHVRNYTIGDVVS  63
            Y+   IE K Q  W +N TF  + D++K KFY L MFPYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RFQRLQGKNVLQPIGWDAFGLPAENAAVKNNTAPAPWTYENIEYMKNQLKLLGFGYDWNR  123
            RF+R QG NVL+P+GWDAFGLPAE+ A+     PA  T ENI   K Q++ LGF+YDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EFATCRPEYYRWEQEFFTKLFAKGLVYKKTSSVNWCPNDQTVLANEQV-EDGCCWRCDTP  182
            E  T  P+YY+W Q +FTKL+ KGL Y    +VNW  +  T +ANE+V  DG   R + P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VEQKEIPQWFIKITAYAQELLDDLDNLDGWPEMVKTMQRNWIGRSEGVELKFAVKGENTD  242
            V +K + QW +KITAYA+ LL+DL+++D WPE +K MQRNWIG+S G ++ F VK+ + D
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LEVYTTRPDTLMGVTYVGIAAGHplatkaaannpalaaFIDECKNTKVAEAEIA----TM  298
            + V+TTRPDTL G TY  +A+ H+L    ++++ A A  + + K      +++A    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEA--VADYKRQASLKSDLARTDLAK  300

Query  299  EKKGMATGLTAIHPLNGREVPIYIANFVLMDYGTGAVMAVPAHDQRDFEFATKYGLDIIP  358
            EK G+ TG  AI+P+NG+E+P+ IA++VL  YGTGA+MAVPAHD+RD EFA ++ LDIIP
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VIKPADGSELDVSEAAYTEKGVLFASGEFDGLDFQAAFNaiaakleaegkgkkTVNFRLR  418
            V+  +     +V EAA+TE G+ + S+ +DGLD  +A+  +   LEAEG G+  V +RLR
Sbjct  361  VLEGG-----NVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  419  DWGVSRQRYWGAPIPMVTTEDGQVHPVPADQLPVILP--EDVVMDGVT-SPIKADKEWAK  475
            DW  SRQRYWG PIP++  EDG   +VP  +LP++LP   D+   G   SP+    +W  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  476  TTF-NGEPALRETDTFDTFMESSWYYARYCSPQADDIL-DPEKANYWLPVDQYIGGIEHA  533
             T  +G  + RET+T      SSWYY RY  P+  + L D E  + WLPVD Y+GG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  534  CMHLLYSRFFHKLLRDAGYVKSDEPFKKLLCQGMVLADAFYYTNDKGGKEWVSPTEVKVE  593
             +HLLY+RF HK+L D G V + EPF+KL+ QGM+L+ +  Y + +G+   + +T+    
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS--YRDSRGA---LVATDKVEK  590

Query  594  RDGKGRIVSAVDATGRQVEHSGMIKMSKSKNNGIDPQEMVDKYGADTVRLFMMFASPADM  653
            RDG    V     TG ++E++   KMSKS +N ++P+++V++YGADT+R++ MF +P D 
Sbjct  591  RDGSFFHV----ETGEELEQAP-AKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  654  TLEWQESGVEGANRFLRRVWKLVREHTELGQAPALDASALNADQKALRRDVHKTIAKVTD  713
            ++ W E G+EG+ +FL RV +L+       + ++           AL +  + T+  VT+
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLITTKEITEENSG-----------ALDKVYNETVKAVTE  694

Query  714  DVARRQTFNTAIAAIMELMNKLTKAPMTEAQDRAILDEALKAITLMLYPITPHICFEMWV  773
            +V + + FNTAIA +M ++N       +  ++  ++ +  K++  ++ P++PH+  E+W 
Sbjct  695  QVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  774  ALGQS--NIDTASWPTYDEAALVEDEKLIVLQVNGKLRGKLTVAADATQQQVEALGMQDE  831
            AL  S  +I   +WP+YDE+ LVE++  IV+Q++GK+++KL VA D ++++++ +++ +E
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  832  NVQKFIDGLTVRKVIYVPGKLLNIVAN  858
            +VQ  I G  + KVI VP KL+NIV +
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVIK  833

1286) leuS in NC_002505


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  535 bits (2018),  Expect = 5e-153, Method: Compositional matrix adjust.
 Identities = 374/867 (44%), Positives = 561/867 (65%), Gaps = 50/867 (5%)

Query  5    YNPQDIEHKVQQHWDNNKTFVVSEDPNKEKFYCLSMFPYPSGR-LHMGHVRNYTIGDVVS  63
            Y+   IE K Q  W +N TF  + D++K KFY L MFPYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RFQRLQGKNVLQPIGWDAFGLPAENAAVKNNTAPAPWTYENIEYMKNQLKLLGFGYDWNR  123
            RF+R QG NVL+P+GWDAFGLPAE+ A+     PA  T ENI   K Q++ LGF+YDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EFATCRPEYYRWEQEFFTKLFAKGLVYKKTSSVNWCPNDQTVLANEQV-EDGCCWRCDTP  182
            E  T  P+YY+W Q +FTKL+ KGL Y    +VNW  +  T +ANE+V  DG   R + P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VEQKEIPQWFIKITAYAQELLDDLDNLDGWPEMVKTMQRNWIGRSEGVELKFAVKGENTD  242
            V +K + QW +KITAYA+ LL+DL+++D WPE +K MQRNWIG+S G ++ F VK+ + D
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LEVYTTRPDTLMGVTYVGIAAGHplatkaaannpalaaFIDECKNTKVAEAEIA----TM  298
            + V+TTRPDTL G TY  +A+ H+L    ++++ A A  + + K      +++A    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEA--VADYKRQASLKSDLARTDLAK  300

Query  299  EKKGMATGLTAIHPLNGREVPIYIANFVLMDYGTGAVMAVPAHDQRDFEFATKYGLDIIP  358
            EK G+ TG  AI+P+NG+E+P+ IA++VL  YGTGA+MAVPAHD+RD EFA ++ LDIIP
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VIKPADGSELDVSEAAYTEKGVLFASGEFDGLDFQAAFNaiaakleaegkgkkTVNFRLR  418
            V+  +     +V EAA+TE G+ + S+ +DGLD  +A+  +   LEAEG G+  V +RLR
Sbjct  361  VLEGG-----NVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  419  DWGVSRQRYWGAPIPMVTTEDGQVHPVPADQLPVILP--EDVVMDGVT-SPIKADKEWAK  475
            DW  SRQRYWG PIP++  EDG   +VP  +LP++LP   D+   G   SP+    +W  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  476  TTF-NGEPALRETDTFDTFMESSWYYARYCSPQADDIL-DPEKANYWLPVDQYIGGIEHA  533
             T  +G  + RET+T      SSWYY RY  P+  + L D E  + WLPVD Y+GG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  534  CMHLLYSRFFHKLLRDAGYVKSDEPFKKLLCQGMVLADAFYYTNDKGGKEWVSPTEVKVE  593
             +HLLY+RF HK+L D G V + EPF+KL+ QGM+L+ +  Y + +G+   + +T+    
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS--YRDSRGA---LVATDKVEK  590

Query  594  RDGKGRIVSAVDATGRQVEHSGMIKMSKSKNNGIDPQEMVDKYGADTVRLFMMFASPADM  653
            RDG    V     TG ++E++   KMSKS +N ++P+++V++YGADT+R++ MF +P D 
Sbjct  591  RDGSFFHV----ETGEELEQAP-AKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  654  TLEWQESGVEGANRFLRRVWKLVREHTELGQAPALDASALNADQKALRRDVHKTIAKVTD  713
            ++ W E G+EG+ +FL RV +L+       + ++           AL +  + T+  VT+
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLITTKEITEENSG-----------ALDKVYNETVKAVTE  694

Query  714  DVARRQTFNTAIAAIMELMNKLTKAPMTEAQDRAILDEALKAITLMLYPITPHICFEMWV  773
            +V + + FNTAIA +M ++N       +  ++  ++ +  K++  ++ P++PH+  E+W 
Sbjct  695  QVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  774  ALGQS--NIDTASWPTYDEAALVEDEKLIVLQVNGKLRGKLTVAADATQQQVEALGMQDE  831
            AL  S  +I   +WP+YDE+ LVE++  IV+Q++GK+++KL VA D ++++++ +++ +E
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  832  NVQKFIDGLTVRKVIYVPGKLLNIVAN  858
            +VQ  I G  + KVI VP KL+NIV +
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVIK  833

1287) leuS in NC_018691


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  535 bits (2019),  Expect = 5e-153, Method: Compositional matrix adjust.
 Identities = 362/857 (43%), Positives = 539/857 (63%), Gaps = 73/857 (8%)

Query  5    YRPDQVEREAQEYWENQETFKVTEQPGKEKFYCLSMFPYPSGR-LHMGHVRNYTIGDVIS  63
            Y    +E   Q +W +++TFK   +++K KFY L MFPYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMQGKNVLQPMGWDAFGLPAENAAIKNKVAPAKWTFENIDYMKGQLKRLGFGYDWDR  123
            R++R QG NVL+PMGWDAFGLPAE+ A+     PA  T ENI   K Q++ LGF+YDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATYTPEYYRWEQWFFTKLYEKGLVYRKMSTVNWDPEDQTVLANEQVI-DGRGWRSGAL  182
            E+ T  P+YY+W QW+FTKLYEKGL Y     VNW  E  T +ANE+V+ DG + R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VEQKEIPQWFIKITDYADELLNDLDQLDGWPEQVKTMQRNWIGRSEGVEMAFAI-DGEEP  241
            V +K + QW +KIT YA+ LL+DL+++D WPE +K MQRNWIG+S G +++F + D +  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  242  LRVYTTRPDTLMGVSY--VavaaahplakkaaaanhevaDFV-EECLHNKVAEADMATME  298
            + V+TTRPDTL G +Y  +A   A   A  ++   + VAD+  +  L + +A +D+A  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  299  KKGIFTGLHATHPISGEQVPVWVANFVLMSYGTGAVMAVPAHDQRDFEFARKYDLPIKQV  358
            K G+ TG  A +P++G ++PVW+A++VL SYGTGA+MAVPAHD+RD EFA++++L I  V
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  359  IEPANGEAIDLEKEAFTGKGRLVNSAGFSGNTSAEAFDAIAAWLNERGLGEKKVNYRLRD  418
            +E +N     +E  AFT  G  +NS  + G   A A+  +  WL+  G+G+ +V YRLRD
Sbjct  362  LEGGN-----VEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  419  WGVSRQRYWGAPIPMVETEDGGLHPTPEDQLPVALPTDVEM---DGVKSPIKADPEWAKT  475
            W  SRQRYWG PIP+++ EDG   + PE +LP+ LP   ++   +   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  476  TW-NGQPALRETDTFDTFMESSWYYARYCCPRNDQAMLDPAAANYWLPVDQYVGGIEHAI  534
            T+ +G  + RET+T      SSWYY RY  P+N + + D    + WLPVD YVGG EHA+
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  535  LHLLYSRFFHKLMRDAGLLDSDEPFKRLLCQGMVL-------------------KDG---  572
            LHLLY+RF HK++ D G++ + EPF++L+ QGM+L                   +DG   
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFF  596

Query  573  ------------AKMSKSKGNTVDPQQMIEQYGADTVRLFMMFAAPPEQSLEWNDTGVEG  620
                        AKMSKS  N V+P++++EQYGADT+R++ MF +P + S+ W++ G+EG
Sbjct  597  HVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEG  656

Query  621  AHRFIKRLWRMV-AEHVEGGATPALDPSALSADAKAVRRKTHETIQKVSDDFSRRYTFNT  679
            +++F+ R+ R++ + ++    + ALD            +  +ET++ V+++  +   FNT
Sbjct  657  SRKFLDRVYRLITTKEITEENSGALD------------KVYNETVKAVTEQVDQM-KFNT  703

Query  680  AIAAVMELINDTGRLAAEDEQARAVRQEALEAAVLLLSPIIPHAAHQLWRALGHDDAVID  739
            AIA +M ++N + +          +  +   + V L++P+ PH +++LW+AL   +  I 
Sbjct  704  AIAQLMVFVNAANK-------EDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESIS  756

Query  740  AV-WPEVDESALVKDSVELVVQVNGKVRAKLEAPADADNAALETLAMAEENVRKFIDGNT  798
             V WP  DES LV + VE+VVQ++GKV+AKL  + D     L+ +A+A+E+V+  I G+ 
Sbjct  757  YVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKD  816

Query  799  VRKVIVVPGKLVNIVAN  815
            + KVI VP KLVNIV +
Sbjct  817  IIKVIAVPNKLVNIVIK  833

1288) leuS in NC_013282


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  535 bits (2019),  Expect = 5e-153, Method: Compositional matrix adjust.
 Identities = 356/866 (42%), Positives = 547/866 (64%), Gaps = 48/866 (5%)

Query  41   YRPEEIESKVQLHWEEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIA  99
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  100  RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNINYMKNQLKMLGFGYDWSR  159
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NI   K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  160  ELATCTPEYYRWEQQFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  218
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  219  VERKEIPQWFIKITAYADELLNDLDKLDQWPDTVKTMQRNWIGRSEGVEITFDVQNSDEK  278
            V RK + QW +KITAYA+ LL+DL+ +D WP+++K MQRNWIG+S G ++TF V+++D  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  279  LTVYTTRPDTFMGVTYlavaaghplaqaaaaanpalGDFIAECRNTKVAEADMA----TM  334
            +TV+TTRPDT+ G TY     +   A   A + +  ++ +A+ +      +D+A    + 
Sbjct  243  FTVFTTRPDTLFGATY--AVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  335  EKKGVDTGIKAIHPLTGEAIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFATKYSLQIKP  394
            EK GV TG  AI+P+ G  +PVW A++VL  YGTGA+MAVP+HD+RD EFA +++L+I P
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  395  VILTAEGTEPDLSEQALTEKGVLFNSGEFDGLDFEAAFNAIADRLAAKGVGERKVNYRLR  454
            V+        ++ E A+TE G+ +NS+ +DGLD  +A+  + ++L A GVG+ +V YRLR
Sbjct  361  VL-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  455  DWGVSRQRYWGAPIPMVTLEDGTVMPTPADQLPVILP--EDVVMDGIT-SPIKADPEWAK  511
            DW  SRQRYWG PIP++  EDGT  + P  +LP++LP   D+   G   SP+    +W  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  512  TT-VNGQPALRETDTFDTFMESSWYYARYTCPQYKEGMLDEKAANYWLPVDIYIGGIEHA  570
             T  +G  + RET+T      SSWYY RY  P+  E + DE   + WLPVDIY+GG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  571  IMHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGQNGERNWVSPKDAIVE  630
            ++HLLY RF HK++ D G+V + EP ++L+ QGM+L+ ++      + R  + + D +  
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEK  590

Query  631  RDEKGRIVKASDAAGHELVYTGMSKMSKSKNNGIDPQEMVERYGADTVRLFMMFASPADM  690
            RD     V +++   +     + +KMSKS +N ++P+++VE+YGADT+R++ MF +P D 
Sbjct  591  RDGSFFHVETGEELEQ-----APAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  691  TLEWQESGVEGANRFLKRVWRLVYEHTALGDAPALNVDALNDDQKALRRDVHKTIAKVSD  750
            ++ W E G+EG+ +FL RV RL+              +  +++  AL +  + T+  V++
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLI-----------TTKEITEENSGALDKVYNETVKAVTE  694

Query  751  DIGRRQTFNTAIAAIMELMNKLAKAPQEGEQDRALMREALLAVVRMLNPFTPHVSFTLWQ  810
            ++++ + FNTAIA +M ++N        ++++  L  +   + V+++ PF+PH++  LWQ
Sbjct  695  QVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  811  ELKGEGD-IDNAPWPQADESAMVEDTTLVVVQVNGKVRGKITVAADATEEQVRERAAQEH  869
             L + G+ I   PWP  DES +VE+   +VVQ++GKV++K+ VA D + E+++E A  ++
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  870  LVAKYLAGVTVRKVIYVPGKLLNLVV  895
             V   +AG  + KVI VP KL+N+V+
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVI  832

1289) DP2600 in NC_006138


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  535 bits (2018),  Expect = 5e-153, Method: Compositional matrix adjust.
 Identities = 353/843 (42%), Positives = 528/843 (63%), Gaps = 72/843 (8%)

Query  9    YDFKTIESKWQKNWAENKTYSVTEDEDKEKYYLLEMFPYPSGR-IHMGHVRNYTIGDVVA  67
            YD  +IE+KWQ  WA+N T+    D  K K+Y L+MFPYPSG  +H+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  68   RYKRMRGFNVLHPMGWDAFGLPAENAAQKNNTHPSVWTYDNIDYMRQQLQQLGLSYDWDR  127
            R+KR +G NVLHPMGWDAFGLPAE+ A     +P+  T +NI   ++Q++ LG+SYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  128  EMATCNPKYYRQEQQLFIEMLEKGLIYEKVTTVNWCDTCQTVLANEQVI-EGACWRCDQL  186
            E+ T +P+YY+  Q +F  + EKGL YE    VNW +   T +ANE+V+ +G+  R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  187  VHPRKMNGWFFKITDYAEELLADLDKLTGWPEKVRTMQRNWIGKSTGLSCDFQLEDMDDK  246
            V  + M  W +KIT YAE LL DL+ + +WPE ++ MQRNWIGKSTG +  F++ D D  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  247  ISIFTTRPDTIYGVTFMSLAPEHPLVEQLIAGTDREQEVRDFVKEVLEDKQRQDPTQEPE  306
            +++FTTRPDT++G T+  LAPEH+LV+  I+ +D+ + V D+ ++     +        E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDA-ITTSDQAEAVADYKRQASLKSDLARTDLAKE  301

Query  307  KKGIFTGKYCTNPFNGDRVPVYVANFVLIEYGTGAVMAVPAHDQRDFEFAGKYKLPIIPV  366
            K G+ TG Y  NP NG  +PV +A++VL  YGTGA+MAVPAHD+RD EFA +++L IIPV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  367  VVPEGEAVNPADMEEALTNHGLLINSGDFTGMASQEAQAKIIAYAEEKGFGSPLTTYRLR  426
            +  EG  V+    E A+T++GL INS+ + G+    A AK++   E  G G+   TYRLR
Sbjct  362  L--EGGNVE----EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  427  DWGISRQRYWGAPIPIIHCDSCGIVPVPIDQLPVELPEDKD---KSSVCAPLHQRPDFIN  483
            DW +SRQRYWG PIPIIH +     +VP  +LP+ LP  KD    ++  +PL +  D ++
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  484  TTCPKCGQPAKRETDTMDTFVESSWYFARYTSPRHTEAPLDKAKAKYWLAVDQYIGGVEH  543
             T    G  ++RET+TM     SSWY+ RY  P++TE   D    K WL+VD Y+GG EH
Sbjct  476  VTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEH  534

Query  544  AILHLLYSRFFTKVLRDLGYLEIDEPFIKLLTQGMVI-------------------KDGT  584
            A+LHLLY+RF  KVL DLG +   EPF KL+ QGM++                   +DG+
Sbjct  535  AVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGS  594

Query  585  ---------------KMSKSKGNVVDPHDLISEFGADTTRLFSLFAAPPERDLEWSSEGV  629
                           KMSKS  NVV+P+D++ ++GADT R++ +F +P +  + WS EG+
Sbjct  595  FFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGL  654

Query  630  EGSSRFLNRIYRFITANFEALTAGEAFPKKLSEEDR-LLHRKNHQTIKRVTENIEHNFHF  688
            EGS +FL+R+YR+IT+            K ++EE+   L++  ++T+K VTE++++   F
Sbjct  655  EGSRKFLDRVYRLITT------------KEITEENSGALDKVYNETVKAVTEQVDQ-MKF  701

Query  689  NTAISAVMELVNQLFAQFKNEKSIAAPAVLRASVDSVLLLLSPMVPHFCNEMWMVL-GNT  747
            NTAI+ +M +VN   A  K++K      ++     + + L++P  PH+ +E+W  L ++ 
Sbjct  702  NTAIAQLMVFVN---AANKEDK------LFSDYAKGFVQLIAPFAPHLGEELWQALTASG  752

Query  748  EPIENQAWPEFDIEATKEDLLTIIIQVRGKVRSKIQVPVDIEEDEIVALALADENCQKFI  807
            E+I   +WP +D     E+ + I++Q++GKV++K+ V+ D+  +E+  +ALA+E+ Q  I
Sbjct  753  ESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEI  812

Query  808  DGQ  810
             G+
Sbjct  813  AGK  815

1290) leuS in NC_006177


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  535 bits (2018),  Expect = 5e-153, Method: Compositional matrix adjust.
 Identities = 374/894 (42%), Positives = 551/894 (62%), Gaps = 103/894 (11%)

Query  6    FDFREAEPRWQRRWDEEGIYKVERDLSRPKYYALAMFPYPSGK-LHMGHVRNYTIVDVIA  64
            +D    EP+WQ  W ++  +K   D S+PK+YAL MFPYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  65   RYRRMKGYNVLHPMGFDSFGMPAENAAIQHGANPAVWTRENIAEMTAQLKQMGYSYDWSR  124
            R++R +G NVLHPMG D+FG+PAE+ A++ G +PA  T ENIA+   Q++ +G+SYDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  125  AVYTYREDYYRWTQWLFLQFYKKGLAYKKTAPVNWCPSCQTVLANEQV-EDGRCWRCDSV  183
             V T   +YY+WTQW+F ++Y KGLAY    PVNW     T +ANE+V  DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  184  VTKKDLAQWFFRITQYAdelledlklleGGWPEQVRIMQQNWIGRSEGARVEFTLEATGD  243
            V +K + QW ++IT YA+ LLEDL  +  +WPE ++ MQ+NWIG+S GA V F +  T+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV--DWPESIKDMQRNWIGKSTGANVTFKVKDTDK  241

Query  244  KIPIFTTRPDTIYGVTFMVVAPEHPIVEKICTSGLIPEERVAAIRAFQEKMKHLSEIART  303
             + +FTTRPDT++G T+ V+APEH++V+ I TS     ++  A+  ++ +    S++ART
Sbjct  242  DFTVFTTRPDTLFGATYAVLAPEHALVDAITTS-----DQAEAVADYKRQASLKSDLART  296

Query  304  STEAEKEGLYTGLDVINPFNGEKAQLWIANYVLMDYGTGAVMGVPAHDQRDFEFAQKYGL  363
                EK G+ TG   INP NG    +WIA+YVL  YGTGA+M+VPAHD+RD EFA+++ L
Sbjct  297  DLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNL  356

Query  364  PVKVVIQNPEGTLRAEEMTAAYVEPGIMVNSGPFDGTPNLEGIPKVIAYAEEQGFGQKTV  423
             +  V++  +         AA+ E G+ +NS+ +DG  +  +I+K++   E +G G+  V
Sbjct  357  DIIPVLEGGNVE------EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENV  410

Query  424  SYRLRDWLISRQRAWGAPIPIVYCDKCGTVPVPEKDLPVRLP--DDLDFTGEGGSPLARH  481
            +YRLRDWL+SRQR WG PIPI+  +   + +VPE +LP+ LP   D+  +G G SPLA  
Sbjct  411  TYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANV  470

Query  482  EGFVNTTCPQCGGPARRETDTMDTFVCSSWYFLRYTDPQNAERPWNREDVDYWMPVDQYV  541
             + ++ T  + G  +RRET+TM     SSWY+LRY DP+N+E+  + E +  W+PVD YV
Sbjct  471  TDWLEVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYV  529

Query  542  GGIEHAVLHLLYARFFTKVLRDMGLVKVDEPFARLLTQGMVL------------------  583
            GG EHAVLHLLYARF  KVL D+G+V   EPF +L+ QGM+L                  
Sbjct  530  GGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVE  589

Query  584  -KDGS---------------KMSKSKGNTVSPEEMIAKYGADAVRLFIMFAAPPERDLDW  627
             +DGS               KMSKS  N V+P++++ +YGAD++R++ MF +P +  + W
Sbjct  590  KRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAW  649

Query  628  SDAGIEGAARFVNRFYRMVVSALPAYQHARSLLPINPADPASVMGALSEAEIAEGLAKAA  687
            S+ G+EG+ +F++R YR++ +                             EI+E      
Sbjct  650  SEEGLEGSRKFLDRVYRLITT----------------------------KEITE------  675

Query  688  PNLTAEDRELRRVIHATVKRITADLHDRFAFNTAISGLMEMTNAIYAYREKQHAEQNTSA  747
                 +   L +V + TVK +T ++ D+  FNTAI+ LM   NA            N   
Sbjct  676  ----ENSGALDKVYNETVKAVTEQV-DQMKFNTAIAQLMVFVNA-----------ANKED  719

Query  748  LVLAEAVQKAVLIIAPFCPHLADELWSRM-GHPRSIHLEPWPAYDEEVAKADTVEIVVQI  806
             ++++  +  V +IAPF PHL++ELW  + +   SI   PWP+YDE     + VEIVVQI
Sbjct  720  KLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQI  779

Query  807  NGRVRDRLEVPAGIsaaemeavamaseKVQALVAGKQIVKVVPVPGKLVNIVVK  860
            +G+V+ +L V+ ++S  E++ VA+A+EKVQA +AGK+I+KV++VP KLVNIV+K
Sbjct  780  KGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

1291) leuS in NC_012578


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  535 bits (2018),  Expect = 6e-153, Method: Compositional matrix adjust.
 Identities = 374/867 (44%), Positives = 561/867 (65%), Gaps = 50/867 (5%)

Query  41   YNPQDIEHKVQQHWDNNKTFVVSEDPNKEKFYCLSMFPYPSGR-LHMGHVRNYTIGDVVS  99
            Y+   IE K Q  W +N TF  + D++K KFY L MFPYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  100  RFQRLQGKNVLQPIGWDAFGLPAENAAVKNNTAPAPWTYENIEYMKNQLKLLGFGYDWNR  159
            RF+R QG NVL+P+GWDAFGLPAE+ A+     PA  T ENI   K Q++ LGF+YDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  160  EFATCRPEYYRWEQEFFTKLFAKGLVYKKTSSVNWCPNDQTVLANEQV-EDGCCWRCDTP  218
            E  T  P+YY+W Q +FTKL+ KGL Y    +VNW  +  T +ANE+V  DG   R + P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  219  VEQKEIPQWFIKITAYAQELLDDLDNLDGWPEMVKTMQRNWIGRSEGVELKFAVKGENTD  278
            V +K + QW +KITAYA+ LL+DL+++D WPE +K MQRNWIG+S G ++ F VK+ + D
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  279  LEVYTTRPDTLMGVTYVGIAAGHplatkaaannpalaaFIDECKNTKVAEAEIA----TM  334
            + V+TTRPDTL G TY  +A+ H+L    ++++ A A  + + K      +++A    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEA--VADYKRQASLKSDLARTDLAK  300

Query  335  EKKGMATGLTAIHPLNGREVPIYIANFVLMDYGTGAVMAVPAHDQRDFEFATKYGLDIIP  394
            EK G+ TG  AI+P+NG+E+P+ IA++VL  YGTGA+MAVPAHD+RD EFA ++ LDIIP
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  395  VIKPADGSELDVSEAAYTEKGVLFASGEFDGLDFQAAFNaiaakleaegkgkkTVNFRLR  454
            V+  +     +V EAA+TE G+ + S+ +DGLD  +A+  +   LEAEG G+  V +RLR
Sbjct  361  VLEGG-----NVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  455  DWGVSRQRYWGAPIPMVTTEDGQVHPVPADQLPVILP--EDVVMDGVT-SPIKADKEWAK  511
            DW  SRQRYWG PIP++  EDG   +VP  +LP++LP   D+   G   SP+    +W  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  512  TTF-NGEPALRETDTFDTFMESSWYYARYCSPQADDIL-DPEKANYWLPVDQYIGGIEHA  569
             T  +G  + RET+T      SSWYY RY  P+  + L D E  + WLPVD Y+GG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  570  CMHLLYSRFFHKLLRDAGYVKSDEPFKKLLCQGMVLADAFYYTNDKGGKEWVSPTEVKVE  629
             +HLLY+RF HK+L D G V + EPF+KL+ QGM+L+ +  Y + +G+   + +T+    
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS--YRDSRGA---LVATDKVEK  590

Query  630  RDGKGRIVSAVDATGRQVEHSGMIKMSKSKNNGIDPQEMVDKYGADTVRLFMMFASPADM  689
            RDG    V     TG ++E++   KMSKS +N ++P+++V++YGADT+R++ MF +P D 
Sbjct  591  RDGSFFHV----ETGEELEQAP-AKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  690  TLEWQESGVEGANRFLRRVWKLVREHTELGQAPALDASALNADQKALRRDVHKTIAKVTD  749
            ++ W E G+EG+ +FL RV +L+       + ++           AL +  + T+  VT+
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLITTKEITEENSG-----------ALDKVYNETVKAVTE  694

Query  750  DVARRQTFNTAIAAIMELMNKLTKAPMTEAQDRAILDEALKAITLMLYPITPHICFEMWV  809
            +V + + FNTAIA +M ++N       +  ++  ++ +  K++  ++ P++PH+  E+W 
Sbjct  695  QVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  810  ALGQS--NIDTASWPTYDEAALVEDEKLIVLQVNGKLRGKLTVAADATQQQVEALGMQDE  867
            AL  S  +I   +WP+YDE+ LVE++  IV+Q++GK+++KL VA D ++++++ +++ +E
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  868  NVQKFIDGLTVRKVIYVPGKLLNIVAN  894
            +VQ  I G  + KVI VP KL+NIV +
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVIK  833

1292) leuS in NC_012668


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  535 bits (2018),  Expect = 6e-153, Method: Compositional matrix adjust.
 Identities = 374/867 (44%), Positives = 561/867 (65%), Gaps = 50/867 (5%)

Query  25   YNPQDIEHKVQQHWDNNKTFVVSEDPNKEKFYCLSMFPYPSGR-LHMGHVRNYTIGDVVS  83
            Y+   IE K Q  W +N TF  + D++K KFY L MFPYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  84   RFQRLQGKNVLQPIGWDAFGLPAENAAVKNNTAPAPWTYENIEYMKNQLKLLGFGYDWNR  143
            RF+R QG NVL+P+GWDAFGLPAE+ A+     PA  T ENI   K Q++ LGF+YDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  144  EFATCRPEYYRWEQEFFTKLFAKGLVYKKTSSVNWCPNDQTVLANEQV-EDGCCWRCDTP  202
            E  T  P+YY+W Q +FTKL+ KGL Y    +VNW  +  T +ANE+V  DG   R + P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  203  VEQKEIPQWFIKITAYAQELLDDLDNLDGWPEMVKTMQRNWIGRSEGVELKFAVKGENTD  262
            V +K + QW +KITAYA+ LL+DL+++D WPE +K MQRNWIG+S G ++ F VK+ + D
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  263  LEVYTTRPDTLMGVTYVGIAAGHplatkaaannpalaaFIDECKNTKVAEAEIA----TM  318
            + V+TTRPDTL G TY  +A+ H+L    ++++ A A  + + K      +++A    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEA--VADYKRQASLKSDLARTDLAK  300

Query  319  EKKGMATGLTAIHPLNGREVPIYIANFVLMDYGTGAVMAVPAHDQRDFEFATKYGLDIIP  378
            EK G+ TG  AI+P+NG+E+P+ IA++VL  YGTGA+MAVPAHD+RD EFA ++ LDIIP
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  379  VIKPADGSELDVSEAAYTEKGVLFASGEFDGLDFQAAFNaiaakleaegkgkkTVNFRLR  438
            V+  +     +V EAA+TE G+ + S+ +DGLD  +A+  +   LEAEG G+  V +RLR
Sbjct  361  VLEGG-----NVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  439  DWGVSRQRYWGAPIPMVTTEDGQVHPVPADQLPVILP--EDVVMDGVT-SPIKADKEWAK  495
            DW  SRQRYWG PIP++  EDG   +VP  +LP++LP   D+   G   SP+    +W  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  496  TTF-NGEPALRETDTFDTFMESSWYYARYCSPQADDIL-DPEKANYWLPVDQYIGGIEHA  553
             T  +G  + RET+T      SSWYY RY  P+  + L D E  + WLPVD Y+GG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  554  CMHLLYSRFFHKLLRDAGYVKSDEPFKKLLCQGMVLADAFYYTNDKGGKEWVSPTEVKVE  613
             +HLLY+RF HK+L D G V + EPF+KL+ QGM+L+ +  Y + +G+   + +T+    
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS--YRDSRGA---LVATDKVEK  590

Query  614  RDGKGRIVSAVDATGRQVEHSGMIKMSKSKNNGIDPQEMVDKYGADTVRLFMMFASPADM  673
            RDG    V     TG ++E++   KMSKS +N ++P+++V++YGADT+R++ MF +P D 
Sbjct  591  RDGSFFHV----ETGEELEQAP-AKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  674  TLEWQESGVEGANRFLRRVWKLVREHTELGQAPALDASALNADQKALRRDVHKTIAKVTD  733
            ++ W E G+EG+ +FL RV +L+       + ++           AL +  + T+  VT+
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLITTKEITEENSG-----------ALDKVYNETVKAVTE  694

Query  734  DVARRQTFNTAIAAIMELMNKLTKAPMTEAQDRAILDEALKAITLMLYPITPHICFEMWV  793
            +V + + FNTAIA +M ++N       +  ++  ++ +  K++  ++ P++PH+  E+W 
Sbjct  695  QVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  794  ALGQS--NIDTASWPTYDEAALVEDEKLIVLQVNGKLRGKLTVAADATQQQVEALGMQDE  851
            AL  S  +I   +WP+YDE+ LVE++  IV+Q++GK+++KL VA D ++++++ +++ +E
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  852  NVQKFIDGLTVRKVIYVPGKLLNIVAN  878
            +VQ  I G  + KVI VP KL+NIV +
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVIK  833

1293) leuS in NC_016445


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  535 bits (2018),  Expect = 6e-153, Method: Compositional matrix adjust.
 Identities = 374/867 (44%), Positives = 561/867 (65%), Gaps = 50/867 (5%)

Query  41   YNPQDIEHKVQQHWDNNKTFVVSEDPNKEKFYCLSMFPYPSGR-LHMGHVRNYTIGDVVS  99
            Y+   IE K Q  W +N TF  + D++K KFY L MFPYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  100  RFQRLQGKNVLQPIGWDAFGLPAENAAVKNNTAPAPWTYENIEYMKNQLKLLGFGYDWNR  159
            RF+R QG NVL+P+GWDAFGLPAE+ A+     PA  T ENI   K Q++ LGF+YDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  160  EFATCRPEYYRWEQEFFTKLFAKGLVYKKTSSVNWCPNDQTVLANEQV-EDGCCWRCDTP  218
            E  T  P+YY+W Q +FTKL+ KGL Y    +VNW  +  T +ANE+V  DG   R + P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  219  VEQKEIPQWFIKITAYAQELLDDLDNLDGWPEMVKTMQRNWIGRSEGVELKFAVKGENTD  278
            V +K + QW +KITAYA+ LL+DL+++D WPE +K MQRNWIG+S G ++ F VK+ + D
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  279  LEVYTTRPDTLMGVTYVGIAAGHplatkaaannpalaaFIDECKNTKVAEAEIA----TM  334
            + V+TTRPDTL G TY  +A+ H+L    ++++ A A  + + K      +++A    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEA--VADYKRQASLKSDLARTDLAK  300

Query  335  EKKGMATGLTAIHPLNGREVPIYIANFVLMDYGTGAVMAVPAHDQRDFEFATKYGLDIIP  394
            EK G+ TG  AI+P+NG+E+P+ IA++VL  YGTGA+MAVPAHD+RD EFA ++ LDIIP
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  395  VIKPADGSELDVSEAAYTEKGVLFASGEFDGLDFQAAFNaiaakleaegkgkkTVNFRLR  454
            V+  +     +V EAA+TE G+ + S+ +DGLD  +A+  +   LEAEG G+  V +RLR
Sbjct  361  VLEGG-----NVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  455  DWGVSRQRYWGAPIPMVTTEDGQVHPVPADQLPVILP--EDVVMDGVT-SPIKADKEWAK  511
            DW  SRQRYWG PIP++  EDG   +VP  +LP++LP   D+   G   SP+    +W  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  512  TTF-NGEPALRETDTFDTFMESSWYYARYCSPQADDIL-DPEKANYWLPVDQYIGGIEHA  569
             T  +G  + RET+T      SSWYY RY  P+  + L D E  + WLPVD Y+GG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  570  CMHLLYSRFFHKLLRDAGYVKSDEPFKKLLCQGMVLADAFYYTNDKGGKEWVSPTEVKVE  629
             +HLLY+RF HK+L D G V + EPF+KL+ QGM+L+ +  Y + +G+   + +T+    
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS--YRDSRGA---LVATDKVEK  590

Query  630  RDGKGRIVSAVDATGRQVEHSGMIKMSKSKNNGIDPQEMVDKYGADTVRLFMMFASPADM  689
            RDG    V     TG ++E++   KMSKS +N ++P+++V++YGADT+R++ MF +P D 
Sbjct  591  RDGSFFHV----ETGEELEQAP-AKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  690  TLEWQESGVEGANRFLRRVWKLVREHTELGQAPALDASALNADQKALRRDVHKTIAKVTD  749
            ++ W E G+EG+ +FL RV +L+       + ++           AL +  + T+  VT+
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLITTKEITEENSG-----------ALDKVYNETVKAVTE  694

Query  750  DVARRQTFNTAIAAIMELMNKLTKAPMTEAQDRAILDEALKAITLMLYPITPHICFEMWV  809
            +V + + FNTAIA +M ++N       +  ++  ++ +  K++  ++ P++PH+  E+W 
Sbjct  695  QVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  810  ALGQS--NIDTASWPTYDEAALVEDEKLIVLQVNGKLRGKLTVAADATQQQVEALGMQDE  867
            AL  S  +I   +WP+YDE+ LVE++  IV+Q++GK+++KL VA D ++++++ +++ +E
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  868  NVQKFIDGLTVRKVIYVPGKLLNIVAN  894
            +VQ  I G  + KVI VP KL+NIV +
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVIK  833

1294) leuS in NC_007614


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  535 bits (2018),  Expect = 6e-153, Method: Compositional matrix adjust.
 Identities = 354/873 (41%), Positives = 545/873 (63%), Gaps = 55/873 (6%)

Query  5    YHPQEIESEAQQYWQQTAAFKAVEAPEKRKYYCLSMFPYPSGK-LHMGHVRNYTIGDVLS  63
            Y+   IE+  Q +W +  +FK+   + K K+Y L MFPYPSG  LH+GH   YT  D+LS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYHRMQGYNVLQPMGWDAFGLPAENAAMQNNVPPAKWTYDNIAYMRKQLQSLGLAMDWDR  123
            R+ R QG NVL+PMGWDAFGLPAE+ AM+    PA  T +NIA  ++Q+++LG++ DWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCQPDYYRWNQWLFLRMLEKGLAYRTTGIVNWDPVDQTVLANEQVI-DGRGWRTGAL  182
            E+ T +P+YY+W QW+F ++ EKGLAY +   VNW     T +ANE+V+ DG + R G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VEKHEIPMYYMKITAYADELLEALNALPGWPERVRTMQANWIGKSFGVEVRFPADAESGM  242
            V +  +    +KITAYA+ LLE L+ + +WPE ++ MQ NWIGKS G +V F        
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTD--  240

Query  243  PQDLKVFTTRADTLFGVTYVAVAAEHPVAQHAAKSNPALAAFIEECRQGAMMEAELA---  299
             +D+ VFTTR+DTLFG TY  +A+EH++ +  + S+ A A  + + ++ A + ++LA   
Sbjct  241  -KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEA--VADYKRQASLKSDLARTD  297

Query  300  -TQEKKGRDTGLYVIHPLTGARLPVWIANYVLMGYGEGAVMAVPAHDERDFEFATQYSLP  358
             ++EK G  TG Y I+P+ G  +PVWIA+YVL +YG GA+MAVPAHDERD EFA Q++L 
Sbjct  298  LAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLD  357

Query  359  IRAVIKPVDSGLTVPLAQAYVEHGITFDSGEFSGLAFQPAVDAIAVALQQKGLGEKRVHY  418
            I +V+   +         A+ E+G+ ++S+ + GL   +A+  +   L+  G+G+  V Y
Sbjct  358  IIPVLEGGNVE-----EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTY  412

Query  419  RLRDWGISRQRYWGCPIPLIYCDACGVVPVPDEQLPVVLP--EDLVPDGSGN-PLAKTPS  475
            RLRDW +SRQRYWG PIP+I  +     +VP+ +LP+VLP   D+ P G+G+ PLA+   
Sbjct  413  RLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTD  472

Query  476  FYECSCPRCGQSARRETDTMDTFVDSSWYYIRYACTDQHRAMVDAR-VDYWLPVDQYIGG  534
              E +    G  +RRET+TM    +SSWYY+RY   ++   + D   +  WLPVD Y+GG
Sbjct  473  WLEVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGG  531

Query  535  IEHAILHLLYSRFWSKVMRDLGLVLFDEPFANLLTQGMVLNEIMFRKTGSGRIVYFNPAD  594
             EHA+LHLLY+RFW KV+ DLG+V   EPF +L+ QGM+L              Y ++ +
Sbjct  532  AEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILG-----------TSYRDSRG  580

Query  595  VDIQTDEQGRRIGAVLRADGQPVEAGGIGTMSKSRNNGVDPQKLVEQYGADTARLFMMFA  654
              + TD   +R G+ ++ +       + + MSKS +N V+P+ +VEQYGADT R++ MF 
Sbjct  581  ALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFM  640

Query  655  SPPEQTLEWADAGVEGAFRFLKRLWKQVYDHLQQSGVANGPIPVAGLGPELKALRFQLHQ  714
            +P + ++ W++ G+EG+ +FL R    VY  +    +++        +  L  +    ++
Sbjct  641  GPLDASIAWSEEGLEGSRKFLDR----VYRLITTKEITEEN------SGALDKV---YNE  687

Query  715  TIAKVGDDLGRRHTFNTAIAAVMELMNALGKLQDSSPSARGLMQEALENIVLLLSPIVPH  774
            T+  V +++++   FNTAIA +M ++NA  K +        L  +    +V L++P+ PH
Sbjct  688  TVKAVTEQVDQMK-FNTAIAQLMVFVNAANKEDK-------LFSDYAKGFVQLIAPFAPH  739

Query  775  ICHVLWRELRPGTELLD-QPWPQADVAALVQDEIELIVQVNGKLRGKIRVAADTKPVIVE  833
            + + LW+ L ++ E +   PWP  D + LV++++E++VQ++GK+++K+ VA D     ++
Sbjct  740  LGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQ  799

Query  834  QLALENEQVRRFIDGKAVKKVVMVPGKLVNIVI  866
            ++AL NE+V+  I GK + KV+ VP KLVNIVI
Sbjct  800  EVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

1295) PCC21_012110 in NC_018525


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  535 bits (2018),  Expect = 6e-153, Method: Compositional matrix adjust.
 Identities = 355/876 (41%), Positives = 547/876 (63%), Gaps = 68/876 (7%)

Query  5    YRPEEIEADVQLHWQEKQTFKVTEQPGKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIS  63
            Y    IE+  Q  W +++TFK   +++K K+Y L M+PYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYANIDYMKNQLKLLGFGYDWDR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T  NI   K Q++ LGF+YDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVATCKPDYYRWEQWFFTKLYEKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            EV T  P+YY+W QW+FTKLYEKGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADQLLNDLDTLESWPEQVKTMQRNWIGRSEGVEITFDVADSDEK  242
            V RK + QW +KITAYA++LL+DL+ ++ WPE +K MQRNWIG+S G ++TF V D+D  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGVTYVavaaghplaaqaaatnpalaDFIAECRNTKVAEADMA----TM  298
            +TV+TTRPDT+ G TY     +   A   A T +  A+ +A+ +      +D+A    + 
Sbjct  243  FTVFTTRPDTLFGATYA--VLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  299  EKKGMATGLYAIHPLNGEKVAIWVANFVLMEYGTGAVMAVPGHDQRDWEFATKYDLSIKP  358
            EK G+ TG YAI+P+NG  +++W+A++VL  YGTGA+MAVP+HD+RDWEFA +++L I P
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VILNADGSEPDLSAQAMTEKGSLFNSGEFDGLDFEAGFNAIADKLVEKGIGERKVNYRLR  418
            V+  ++  E+ ++ +++  ++ +     +DGLD  +++  + + L   G+G+ +V YRLR
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDF-----LDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  419  DWGVSRQRYWGAPIPMVTLEDGTVIPTPEDQLPVILP--EDVVMDGIT-SPLKSNPEWAK  475
            DW  SRQRYWG PIP++  EDGT  + PE +LP++LP   D+   G   SPL +  +W  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  476  TT-VNGQPALRETDTFDTFMESSWYYARYTCPQYDQGMLDPAAANYWLPVDQYVGGIEHA  534
             T  +G  + RET+T      SSWYY RY  P+  + + D    + WLPVD YVGG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  535  IMHLMYFRFFHKLMRDAGLVTSDEPAKRLLCQGMVLADAFYYLGNNGERIWVSPTDVTVE  594
            ++HL+Y RF HK++ D G+V + EP ++L+ QGM+L+ ++                    
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY--------------------  575

Query  595  RDEKGRIVKAVDNEGRDVVY----------AGMSKMSKSKNNGIDPQVMVEKYGADTVRL  644
            RD +G +V +   E RD  +           + +KMSKS +N ++P+ +VE+YGADT+R+
Sbjct  576  RDSRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRV  635

Query  645  FMMFASPAEMTLEWQESGVEGANRFLKRVWRQAFEHTEKGAVTALDIATLTEDQKSLRRD  704
            + MF +P + ++ W E G+EG+ +FL RV R          +T+ +I+   E+  +L + 
Sbjct  636  YEMFMGPLDASIAWSEEGLEGSRKFLDRVYRL---------ITTKEIT--EENSGALDKV  684

Query  705  LHKTIAKVTDDIGRRQTFNTAIAAIMELMNKLAKAPQDSDQDRALTQEIMLAVVRMLYPF  764
             + T+  VT+++++ + FNTAIA +M ++N        ++++  L  +   + V+++ PF
Sbjct  685  YNETVKAVTEQVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPF  736

Query  765  TPHVCFTLWQALQGEGD-VDTAPWPVADENAMVEDSKLVVVQVNGKVRGKITVAADASEE  823
            +PH+   LWQAL + G+ +   PWP  DE+ +VE+   +VVQ++GKV++K+ VA D S E
Sbjct  737  APHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSRE  796

Query  824  QVRERAAQEPLVAKYLDGVTVRKVIYVPGKLLNLVV  859
            +++E A  +  V   + G  + KVI VP KL+N+V+
Sbjct  797  ELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

1296) Tery_1704 in NC_008312


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  534 bits (2015),  Expect = 1e-152, Method: Compositional matrix adjust.
 Identities = 327/673 (49%), Positives = 466/673 (70%), Gaps = 13/673 (1%)

Query  5    YNPVSIEQKWQKNWAEQNQDQTPINNNQPKFYALSMFPYPSG-NLHMGHVRNYTITDVIA  63
            Y+  +IE KWQ  WA+++  +T  + ++PKFYAL MFPYPSG  LH+GH   YT TD+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RLKRMQGYRVLHPMGWDAFGLPAENAAIDRGIPPAKWTLENIAQMKEQLRRLGFSIDWDK  123
            R+KR QG  VLHPMGWDAFGLPAE+ A+D G  PA  T ENIA+ K Q+  LGFS DWD+
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVATCTPEYYRWTQWIFLQFFQAGLAYQKESAVNWDPIDQTVLANEQVDGEGRSWRSGAK  183
            EV T  P+YY+WTQWIF ++++ GLAY+ E +VNW     T +ANE+V  +G S R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  184  VERKMLRQWFFKITDYAEQLLNDLDKLPGWPERVKLMQANWIGKSVGAYLEFPIVGMDQK  243
            V RK +RQW +KIT YAE+LL+DL+ + +WPE +K MQ NWIGKS GA + F + + D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  244  IGVFTTRPDTVYGVSYVVLAPEHPLTAKVTTPEQQITVETFIKEVAAESELERTAEDKPK  303
            + VFTTRPDT++G +Y VLAPEH+L   +TT++Q  +V  + ++ +  S+L RT   K K
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEK  302

Query  304  RGVPTGGKAINPFNNQEVPIWIADYVLYEYGTGAVMGVPAHDVRDFQFAKQYNLPIKTVI  363
             GV TG+ AINP N +E+P+WIADYVL  YGTGA+M+VPAHD RD +FAKQ+NL I  V+
Sbjct  303  TGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL  362

Query  364  VPDDSNDDHKLTEAYTDVGVMVNSGPFNGEKSTVAKKAIIELAEDEGYGKGRVQYRLRDW  423
              ++ ++      A+T+ G+ +NS+ ++G   + A   ++E  E EG G+  V YRLRDW
Sbjct  363  EGGNVEE-----AAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDW  417

Query  424  LISRQRYWGAPIPIIHCPKCGAVPVPDEDLPVKLPESVEF--SGRGPSPLAKLEDWVNVS  481
            L+SRQRYWG PIPIIH     + +VP+ +LP+ LP + ++  SG G SPLA++ DW++V+
Sbjct  418  LFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT  477

Query  482  CPSCGTPAKRETDTMDTFIDSSWYYLRYPDATNEEQVFDSKIVNDWLPVDQYVGGIEHAI  541
                G  ++RET+TM    +SSWYYLRY D+ N E++ D  ++++WLPVD YVGG EHA+
Sbjct  478  RED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  542  LHLLYSRFFTKVLRDRGLCDFDEPFQNLLTQGMVQGVTYKNPVTGKYIPFADVNPQEPK-  600
            LHLLY+RF  KVL D G+    EPFQ+L+ QGM+ G +Y+++  G  ++   V+ ++   
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDS-RGALVATDKVEKRDGSF  595

Query  601  -DPKTGDKLEVFFEKMSKSKYNGVDPMDVMATYGADTARMFILFKAPPEKDLEWDDADVQ  659
             +  TG+ LE    KMSKS  N V+P DV+  YGADT R++ +F +P +  + W + +++
Sbjct  596  FHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLE  655

Query  660  GQFRFLNRVWSMV  672
            G  +FL+RV  ++
Sbjct  656  GSRKFLDRVYRLI  668


 Score = 87.6 bits (313),  Expect = 4e-18, Method: Compositional matrix adjust.
 Identities = 55/152 (37%), Positives = 106/152 (70%), Gaps = 6/152 (3%)

Query  778  HNAIKEVTEDLDGDYQFNTAVSEMMKLSNALGDASCKDSPIYaealetlllllaPFAPHI  837
            ++++K VTE++D + +FNTA++++M     + +A+ K+  ++++    ++ L+APFAPH+
Sbjct  686  NETVKAVTEQVD-QMKFNTAIAQLM----VFVNAANKEDKLFSDYAKGFVQLIAPFAPHL  740

Query  838  TEELWQ-IAGNFGSVHTHAWPKFDPEALVVDEITLVIQIKGKTRGTIQVPAQADKETLEK  896
             EELWQ ++++  S+   +WP +D   LV +++ +V+QIKGK ++ + V+ +  +E L+ 
Sbjct  741  GEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQE  800

Query  897  LARESDIAQRHLAGKEIKKVIVVPRKLVNFVV  928
            +A  ++  Q ++AGK+I KVI VP KLVN+V+
Sbjct  801  VALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

1297) leuS in NC_011312


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  534 bits (2014),  Expect = 1e-152, Method: Compositional matrix adjust.
 Identities = 368/867 (43%), Positives = 565/867 (66%), Gaps = 50/867 (5%)

Query  5    YNPQDLEQKIQKHWDDSKTFVVTEDASKEKFYCLSMFPYPSGR-LHMGHVRNYTIGDVVS  63
            Y+   +E K Q  W D+ TF    DASK KFY L MFPYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRLQGKNVMQPIGWDAFGLPAENAAVKNKTAPAPWTYENIEYMKNQLKLLGFGYDWSR  123
            R++R QG NV++P+GWDAFGLPAE+ A+     PA  T ENI   K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EFATCTPEYYRWEQEFFTKLYNKGLVYKKTSSVNWCPNDQTVLANEQV-EDGCCWRCDTP  182
            E  T  P+YY+W Q +FTKLY+KGL Y    +VNW  +  T +ANE+V  DG   R + P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VEQKKIPQWFIKITEYAQELLDDLDTLDGWPDMVKTMQRNWIGRSEGVELSFAVNGEEAP  242
            V +K + QW +KIT YA+ LL+DL+ +D WP+ +K MQRNWIG+S G +++F V++ +  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LEVYTTRPDTLMGVTYVGIAAGHPLAEQAAAKNP--ELFAFT-EECRNTKVAEAELATME  299
            + V+TTRPDTL G TY  +A+ H+L +  ++ +    +  +  +   ++ +A ++LA  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGMDTGLRAIHPLNGREVPIYVANFVLMDYGTGAVMAVPAHDQRDYEFATKYGLDIIPV  359
            K G+ TG  AI+P+NG+E+P+ +A++VL  YGTGA+MAVPAHD+RD EFA ++ LDIIPV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  360  IKPEDGSDVDVSDVAYTEKGVLFDSGEFDGLAFQDAFDaiaakleaegkgkkTVNFRLRD  419
            +   +G++V+  + A+TE G+ ++S+ +DGL    A+  +   LEAEG G+  V +RLRD
Sbjct  362  L---EGGNVE--EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMVTTEDGEVHPVPADQLPVILP--EDVVMDGVT-SPIKADKEWAKT  476
            W  SRQRYWG PIP++  EDG   +VP  +LP++LP   D+   G   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  TF-NGEPALRETDTFDTFMESSWYYARYCSPQADDIL-DPEKANYWLPVDQYVGGIEHAC  534
            T  +G  + RET+T      SSWYY RY  P+  + L D E  + WLPVD YVGG EHA 
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  535  MHLLYSRFFHKLLRDAGYVTSNEPFKQLLCQGMVLSDAFHHTNEKGTKEWIAPTDVTIER  594
            +HLLY+RF HK+L D G V ++EPF++L+ QGM+L+ +++++  +G+   + +TD    R
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDS--RGA---LVATDKVEKR  591

Query  595  DAK-GRIEKAVDDQGREVQHSGMIKMSKSKNNGIDPQEMVDKFGADTVRLFMMFAAPADM  653
            D+   ++E      G E++++   KMSKS +N ++P+++V+++GADT+R++ MF +P D 
Sbjct  592  DGSFFHVET-----GEELEQAP-AKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  654  TLEWQESGVEGASRFLKRVWKLVHEHTTKGTTEALDVAALSGDQKALRRDVHKTIAKVSD  713
            ++ W E G+EG+ +FL RV +L+   TTK  TE         +  AL +  + T+  V++
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLI---TTKEITEE--------NSGALDKVYNETVKAVTE  694

Query  714  DIGRRQTFNTAIAAIMELMNKLNKAPQGSAQDRALLDEALKAVVVMLYPMTPHASFAMWE  773
            ++++ + FNTAIA +M ++N       ++ ++  L+ +  K+ V ++ P +PH +  +W+
Sbjct  695  QVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  774  ALGES--NIDTTAWPTFDEKALIEDEKTIVVMINGKLRAKLIVAADATEEQVKELGLNDE  831
            AL  S  +I   +WP++DE  L+E++  IVV I+GK++AKL+VA D + E+++E++L +E
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  832  NALKFLDGLTIRKVIYVPGKLLNIVAN  858
            +    + G  I KVI VP KL+NIV +
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVIK  833

1298) leuS in NC_009792


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  534 bits (2014),  Expect = 1e-152, Method: Compositional matrix adjust.
 Identities = 360/866 (42%), Positives = 549/866 (64%), Gaps = 48/866 (5%)

Query  13   YRPEEIESKVQQHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIA  71
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  72   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSR  131
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  132  ELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  190
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  191  VERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKTMQRNWIGRSEGVEITFDVNGYDNT  250
            V RK + QW +KITAYA+ LL+DL+ +D WP+++K MQRNWIG+S G ++TF V++ D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  251  LTVYTTRPDTFMGATYLAVAAGHPLAQKAAANNPELAAFIDECRNTKVAEADMA----TM  306
            +TV+TTRPDT+ GATY  +A+ H+L +  A   ++ A  + + +      +D+A    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVD--AITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  307  EKKGVDTGFKAIHPLTGEAIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFATKYGLTIKP  366
            EK GV TG  AI+P+ G  +PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L I P
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  367  VILAADGSEPDLSEQALTEKGVLFNSGEFNGLGFEDAFNAIADKLAAKGVGERKVNYRLR  426
            V+        ++ E A+TE G+ +NS+ ++GL+   A+  + + L A GVG+ +V YRLR
Sbjct  361  VL-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  427  DWGVSRQRYWGAPIPMVTLEDGTVLPTPEDQLPVILP--EDVVMDGIT-SPIKADPEWAK  483
            DW  SRQRYWG PIP++  EDGT  + PE +LP++LP   D+   G   SP+    +W  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  484  TT-VNGQPALRETDTFDTFMESSWYYARYTCPQYNEGMLDPEAANYWLPVDIYIGGIEHA  542
             T  +G  + RET+T      SSWYY RY  P+  E + D E  + WLPVDIY+GG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  543  IMHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVE  602
            ++HLLY RF HK++ D G+V + EP ++L+ QGM+L+ ++      + R  + + D +  
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEK  590

Query  603  RDEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADM  662
            RD  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D 
Sbjct  591  RD--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  663  TLEWQESGVEGANRFLKRVWKLVYEHTAKGEVAALNVDALSEDQKALRRDVHKTIAKVTD  722
            ++ W E G+EG+ +FL RV +L+   T+K        +   E+  AL +  + T+  VT+
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLI---TTK--------EITEENSGALDKVYNETVKAVTE  694

Query  723  DIGRRQTFNTAIAAIMELMNKLAKAPQEGEQDRALMQEALLAVVRMLNPFTPHACFTLWE  782
            ++++ + FNTAIA +M ++N        ++++  L  +   + V+++ PF+PH    LW+
Sbjct  695  QVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  783  ALKGEGD-IDNAPWPVADDKAMVEDSTLVVVQVNGKVRGKITVPVNATEEQVRERAGQEH  841
            AL + G+ I   PWP  D+  +VE+   +VVQ++GKV++K+ V+ + + E+++E A  ++
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  842  LVAKYLDGVTVRKVIYVPGKLLNLVV  867
             V   + G  + KVI VP KL+N+V+
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVI  832

1299) D782_3198 in NC_020063


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  534 bits (2014),  Expect = 1e-152, Method: Compositional matrix adjust.
 Identities = 356/866 (42%), Positives = 545/866 (63%), Gaps = 48/866 (5%)

Query  34   YRPEEIESKVQQHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIA  92
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  93   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSR  152
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  153  ELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  211
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  212  VERKEIPQWFIKITAYADELLNDLDTLDHWPDTVKTMQRNWIGRSEGVEISFDVNDYADK  271
            V RK + QW +KITAYA+ LL+DL+ +D WP+++K MQRNWIG+S G +++F V+D    
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  272  LTVYTTRPDTFMGCTYLAVAAGHPLAQQAAVNNPTLAAFVDECRNTKVAEADMA----TM  327
            +TV+TTRPDT+ G TY  +A+ H+L +  A+  +  A  V + +      +D+A    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVD--AITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  328  EKKGVDTGFKAIHPLTGEAIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFATKYGLNIKP  387
            EK GV TG  AI+P+ G  +PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L+I P
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  388  VILAADGSEPDLSEQALTEKGTLFNSGEFDGLSYEEGFNAIADKLAAMGVGERKVNYRLR  447
            V+ +++  E+ ++E++L  ++ +     +DGL    ++  + + L A GVG+ +V YRLR
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDF-----LDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  448  DWGVSRQRYWGAPIPMVTLEDGTVIPTPEDQLPVILP--EDVVMDGIT-SPIKADPEWAK  504
            DW  SRQRYWG PIP++  EDGT  + PE +LP++LP   D+   G   SP+    +W  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  505  TT-VNGRPALRETDTFDTFMESSWYYARYTCPQYQEGMLDSDAANYWLPVDIYIGGIEHA  563
             T  +G  + RET+T      SSWYY RY  P+  E + D +  + WLPVDIY+GG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  564  IMHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGANGERNWVSPVDAIVE  623
            ++HLLY RF HK++ D G+V + EP ++L+ QGM+L+ +  Y ++ G    + + D +  
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS--YRDSRGA---LVATDKVEK  590

Query  624  RDEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADM  683
            RD  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D 
Sbjct  591  RD--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  684  TLEWQESGVEGANRFLKRVWKLVYEHTSQGPVAALNVDALSEDQQALRRDVHKTIAKVTD  743
            ++ W E G+EG+ +FL RV +L+              +   E+  AL +  + T+  VT+
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLI-----------TTKEITEENSGALDKVYNETVKAVTE  694

Query  744  DIGRRQTFNTAIAAIMELMNKLAKAPVEGEQDRALMQEALLAVVRMLNPFTPHASFTLWR  803
            ++++ + FNTAIA +M ++N        ++++  L  +   + V+++ PF+PH +  LW+
Sbjct  695  QVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  804  ELGGVGD-IDNAPWPVADEKAMVENTTLVVVQVNGKVRGKITVAVDATEEQVRERAGQEH  862
             L + G+ I   PWP  DE  +VEN   +VVQ++GKV++K+ VA D + E+++E A  ++
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  863  LVAKYLDGVTVRKVIYVPGKLLNLVV  888
             V   + G  + KVI VP KL+N+V+
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVI  832

1300) leuS in NC_017451


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  534 bits (2014),  Expect = 1e-152, Method: Compositional matrix adjust.
 Identities = 357/866 (42%), Positives = 560/866 (65%), Gaps = 46/866 (5%)

Query  5    YRPDMIEPKVQQYWAENKVFKAIKDESKEKYYCLSMFPYPSGR-LHMGHVRNYTIGDVIS  63
            Y    IEPK Q +WA+N  FK+  D SK K+Y L MFPYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPFGWDAFGLPAEGAAIKNKTAPAKWTYENIAYMKKQLQLLGFGFDWDR  123
            R++R  G NVL+P GWDAFGLPAE  A+     PA  T ENIA  K+Q++ LGF++DWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EIATCKPEYYKWEQWFFTELYKKGLVYKKTSTVNWCPNDETVLANEQV-HEGCCWRCDTP  182
            E+ T  P+YYKW QW+FT LY KGL Y     VNW  +  T +ANE+V  +G   R + P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VEQKEIPQWFIKITDYAEQLLGGLDPLPQWPDMVKTMQRNWIGRSEGVEITFDVADTNEK  242
            V +K + QW +KIT YAE+LL +L+ + +WP+ +K MQRNWIG+S G ++TF V DT+  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  VAVYTTRPDTFYGVSY--LGIaaahplaslaaQNNPELATFIQEAK-NAKVAEADLATME  299
             +V+TTRPDT++G +Y  L+   A   A  ++++   +A + ++A  ++ +A +DLA  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGMATGLFAIHPLTGEKLPIWVANFVLMHYGTGAVMAVPAHDQRDFEFAQKYSLPIKQV  359
            K G+ TG +AI+P+ G  +P+W+A++VL  YGTGA+MAVPAHD+RD EFA++++L   ++
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNL---DI  358

Query  360  IAPLADEEIYLTKQAFVEHGKLVNSAEFDGLDFEGAFNGIADKLEKLSVGKRQVNYRLRD  419
            I+ L + ++     AF E+G  +NS  +DGLD  +A+  + + LE  +VG+ +V YRLRD
Sbjct  359  IPVLEGGNV--EEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMLTLENGDVVPAPIEDLPIILP--EDVVMDGV-KSPIKADPNWAKT  476
            W  SRQRYWG PIP++  E+G   + P  +LP++LP   D+   G   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  TF-NGVPALKETDTFDTFMESSWYYARYTCPQYQNGMLDAEEANYWLPVDQYIGGIEHAT  535
            T  +GV + +ET+T      SSWYY RY  P+  + + D E  + WLPVD Y+GG EHA 
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLLYFRFFHKLLRDAGFVTSDEPADRLLCQGMVLADAFYYTSPTNERIWVSPTQVTLER  595
            +HLLY RF HK+L D G V + EP ++L+ QGM+L+ ++      + R     + V+ ++
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSR----GALVATDK  587

Query  596  DEKGRIIKATDPEGRELVHSGMTKMSKSKNNGIDPQEMVEKYGADTVRLFMMFASPAEMT  655
             EK R     + E  E ++ + +KMSKS +N ++P+++VE+YGADT+R++ MF +P + +
Sbjct  588  VEK-RDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  656  LEWQESGVEGAKRFLGRVWNLVYQYQQNPAKTSLDITALSAEQKVLRREVHKTIAKVSDD  715
            + W E G+EG+++FL+RV  L+         T+ +IT    +   L +  + T+  V+++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLI---------TTKEITE--ENSGALDKVYNETVKAVTEQ  695

Query  716  IGRRQTFNTAIAAVMELMNKLTKASLESDQDRAVMAEALSAVVRMLYPITPHICFELWQA  775
            +++ + FNTAIA +M ++N        ++++  + ++   + V+++ P++PH+  ELWQA
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  776  L-GNESAIDTAEWVKADEAAMVEDEKLIVVQVNGKVRGKVTVAADADEETVKTIAFADEN  834
            L ++  +I    W   DE+ +VE++  IVVQ++GKV++K+ VA D   E ++ +A+A+E+
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  835  VKKFVDNQHIVKVIYVAGKLLNVVVK  860
            V+  +  ++I+KVI V+ KL+N+V+K
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVIK  833

1301) leuS in NC_015761


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  534 bits (2014),  Expect = 1e-152, Method: Compositional matrix adjust.
 Identities = 359/865 (42%), Positives = 555/865 (65%), Gaps = 46/865 (5%)

Query  5    YRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIA  63
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDSK  182
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYAEELLGDLDKLDHWPDTVKTMQRNWIGRSEGVEITFDVKGYDNT  242
            V RK + QW +KITAYAE LL DL+ +D WP+++K MQRNWIG+S G ++TF VK+ D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGATYLAVAAGHPL--SVKAAANNPDLATFIDECR-NTKVAEAEMATME  299
            +TV+TTRPDT+ GATY  +A+ H+L  ++ ++ +   +A +  +   ++ +A +++A  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGVDTGFKAIHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFATKYGLTIKPV  359
            K GV TG  AI+P+ G E+PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L I PV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  360  ILAADGSEPDLSEQALTEKGVLFNSGEFNGLGFEDAFNAIADKLASLGVGERKVNYRLRD  419
            +        ++ E A+TE G+ +NS+ ++GL+   A+  + + L + GVG+ +V YRLRD
Sbjct  362  L-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMVTLEDGTVIPTPEDQLPVILP--EDVVMDGIT-SPIKADPEWAKT  476
            W  SRQRYWG PIP++  EDGT  + PE +LP++LP   D+   G   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  T-VNGMPALRETDTFDTFMESSWYYARYTCPQYQEGMLDSKAANYWLPVDIYIGGIEHAI  535
            T  +G+ + RET+T      SSWYY RY  P+  E + D    + WLPVDIY+GG EHA+
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVER  595
            +HLLY RF HK++ D G+V + EP ++L+ QGM+L+ ++      + R  + + D +  R
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEKR  591

Query  596  DEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMT  655
            D  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D +
Sbjct  592  D--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  656  LEWQESGVEGANRFIKRVWKLVYEHTAKGSVAALNVDTLNDEQKALRRDVHKTIAKVTDD  715
            + W E G+EG+ +F+ RV +L+   T+K        +  +++  AL +  + T+  VT++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLI---TTK--------EITEENSGALDKVYNETVKAVTEQ  695

Query  716  IGRRQTFNTAIAAIMELMNKLAKAPQESEQDRALMHEALLAVVRMLNPFTPHVCFTLWQA  775
            +++ + FNTAIA +M ++N        ++++  L  +   + V+++ PF+PH+   LWQA
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  776  LEGEGD-IDNAPWPVADDKAMVEESTLVVVQVNGKVRGKITVPVNATEEQVRERAGQEHL  834
            L + G+ I   PWP  D+  +VE+   +VVQ++GKV++K+ V+ + + E+++E A  ++ 
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  835  VAKYLDGVTVRKVIYVPGKLLNLVV  859
            V   + G  + KVI VP KL+N+V+
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVI  832

1302) leuS in NC_003103


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  534 bits (2014),  Expect = 1e-152, Method: Compositional matrix adjust.
 Identities = 339/846 (41%), Positives = 554/846 (66%), Gaps = 32/846 (3%)

Query  2    NQIEQKWQYIWQEEKAFEVSNASSKPKYYVLEMLPYPSGK-IHVGHVRNYSIGDVIARFM  60
              IE KWQ +W ++ +F  +  +SKPK+Y L+M+PYPSG  +HVGH   Y+  D+++RF 
Sbjct  7    TAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSRFK  66

Query  61   TMQGFNVLHPMGWDAFGLPAENAAIKNNSHPKKWTYSNIKNMKKQLKSMGFSYDWSREIN  120
              QG NVLHPMGWDAFGLPAE+ A+   ++P   T  NI N K+Q++++GFSYDW RE+N
Sbjct  67   RAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDREVN  126

Query  121  SCDPEYYKHEQKFFLELYERNLAYQKESFVNW-DPVDNTVLANEQVVDGRGWRSGAIVVK  179
            + DP+YYK  Q +F  LYE+ LAY+ E  VNW + ++ ++  +E + DG + R+G  VV+
Sbjct  127  TTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVR  186

Query  180  RYLKQWFLKITDYAEELLNEIQNLKEWPEAVRSMQEKWIGKSIGANFHFKIKDNEETTIE  239
            + ++QW LKIT YAE LL++++++ +WPE+++ MQ +WIGKS GAN  FK+KD  +  + 
Sbjct  187  KPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDT-DKDFT  244

Query  240  VFSTKPETIFGASFIGIAFNHPIIERLVS--KTPEILAFITQC---SHITRSSELEKAEK  294
            VF+T+P+T+FGA++  +A +H++++ + +  ++  +  +  Q    S+++R ++L K EK
Sbjct  245  VFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLAR-TDLAK-EK  302

Query  295  EGVFTGLFVTHPFDSNIVLPVIITNFVLMDYGTGAIFGCPAHDECDHELAVKMNLSIKQV  354
             GV TG +  +P +++  +PV I+++VL  YGTGAI + PAHDE D E+A + NL I  V
Sbjct  303  TGVWTGSYAINPVNGK-EMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  355  IKADMDVQKTAYTEDGILINSDFLNGLTSNEAKQEVIGEFEKLGIGKRSVNYRLKDWGIS  414
            + ++ +V+ +A+TEDG+ INSDFL+GL    A   ++  +E  G+G+ +V YRL+DW +S
Sbjct  362  LEGG-NVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  415  RQRFWGCPIPMIHCEICGIVPVPYKDLPVTLP--DDVNFDGHGN-PLDHHPSWKHVNCPK  471
            RQR+WG PIP+IH E     +VP  +LP+ LP   D+   G G+ PL +   W +V    
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  472  CDKPAVRETDTFDTFFESSWYFTRYCNSNATE-MTDKKACDYWLPVDKYIGGIEHAVMHL  530
              K + RET+T      SSWY+ RY +++ TE ++D      WLPVD Y+GG EHAV+HL
Sbjct  481  GVK-GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHL  539

Query  531  LYARFFTKVMNEQNYVSVREPFKGLFTQGMVLHATYKDEHNNWLYPEEVVKKGNEFFHKE  590
            LYARF  KV+ +   V+ +EPF+ LF QGM+L ++Y+D +   +  + V K++  FFH E
Sbjct  540  LYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVE  599

Query  591  SNNRVVQGRIEKMSKSKKNLIDLETMQEQYGADAIRLFVLSDSPPEKDLEWSASGIEGCS  650
            + + + Q+   KMSKS KN+++ + + EQYGAD++R++ +  +P +  + WS  G+EG  
Sbjct  600  TGEELEQAP-AKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSR  658

Query  651  RFINKLEYMFKAIDSLKDDVNSEVNKELNRLVHFTIKHVAEDIKHFALNRAIARMRELSN  710
            +F+++   +++ I +   ++  E +  L+++ + T+K V+E++ +  +N AIA++  + N
Sbjct  659  KFLDR---VYRLITT--KEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVN  713

Query  711  AISAEISKDKIDVKTVRHGFNVLVQLLNPFIPHITEEIWQKL-GNKERLYNLSFPAFDES  769
            A + E   DK+       GF   VQL+ PF PH+ EE+WQ L ++ E +  ++ P++DES
Sbjct  714  AANKE---DKL-FSDYAKGF---VQLIAPFAPHLGEELWQALTASGESISYVPWPSYDES  766

Query  770  MLELDTYIMAVQVNGKLRDTYEFKTSVSEDEIKQVTVSLPKVQKFLEGKEPKKIILVPRK  829
             L  +   + VQ++GK++        +S +E+++V+++  KVQ  + GK+  K+I VP K
Sbjct  767  KLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNK  826

Query  830  IVNILV  835
            +VNI++
Sbjct  827  LVNIVI  832

1303) Adeh_2727 in NC_007760


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  534 bits (2017),  Expect = 6e-153, Method: Compositional matrix adjust.
 Identities = 351/861 (41%), Positives = 538/861 (63%), Gaps = 68/861 (7%)

Query  33   YEPQSIEPRWQRRWEEAGAFKAGRRPDADTRYVLEMFPYPSGA-MHMGHARVYTIGDALA  91
            Y+  +IEP+WQ  W +  +FK+G  +     Y L+MFPYPSGA +H+GH+  YT  D L+
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  92   RHLRMRGFDVLHPIGFDALGLPAENAAIKDGRHPAERTRENVVSFRAEMKRLGYSFDWDR  151
            R  R +G +VLHP+G DA+GLPAE+ A+  G +PAE T EN+ +F+ +++ LG+S+DWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  152  ELVTADASYYRWNQWFFLKMLEKGIAYRRQGKVNWCTGCQTVIANEQVVDDNRCERCGSP  211
            E+ T+D++YY+W QW+F K+ EKG+AY  +  VNW     T IANE+V+ D   ER G P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  212  VVEKIHPEWAFRITAYAqqlldgldglKDWPDRVTTMQRNWIGKSEGAEVDFALAAGGAA  271
            VV K   +W ++ITAYA++LL++L+ + DWP+ +  MQRNWIGKS GA+V F +   +  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  272  VKVFTTRVDTIYGCTYVVLAPEHPLVAQVTAPDRRAEVDAFVARMRKTDAVERTGEGAPK  331
              VFTTR DT++G TY VLAPEH+LV  +T++D+   V  +  +      + RT+ +  K
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEK  302

Query  332  EGVFTGAFAVNPFTGEQVPIWIANFVLAEYGTGAVMSVPAHDQRDFEFARKYGLPVRVVI  391
             GV TG++A+NP  G ++P+WIA++VLA YGTGA+M+VPAHD+RD EFA+++ L +  V 
Sbjct  303  TGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV-  361

Query  392  QPAQGARLPAGEALERAATEDGVLEGSGPFTGLASAEARTRMSAHAAARGFGQGTVRWHL  451
                   L +G+  E A TEDG+   S+ + GL  A A ++M     A G G+  V  +L
Sbjct  362  -------LEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRL  414

Query  452  RDWGFSRQRYWGTPIPIIYCDEHGMVPVPEQDLPVVLPAEAII--TGTGEPPLAKVASFV  509
            RDW FSRQRYWG PIPII  ++    +VPE +LP+VLP    I  +GTGE+PLA+V+  +
Sbjct  415  RDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWL  474

Query  510  NTTCPRCGKPARREVETMDTFVDSSWYYARYLSPKDEARPFDPEAARRWLPVDVYVGGPE  569
            + T     K +RRE +TM    +SSWYY RY+ P +  +  D E  ++WLPVD+YVGG+E
Sbjct  475  EVTREDGVK-GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAE  533

Query  570  HAVMHLLYFRFWHRVMHELGLVHEDEPVRRLVTQGIVNGP---DGR--------------  612
            HAV+HLLY RFWH+V+ +LG+V   EP ++L  QG++ G    D+R              
Sbjct  534  HAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDG  593

Query  613  ----------------KMSKRWGNVVAPGGMVSRFGADTVRMFMLFAAPPEKDIDWSDEQ  656
                            KMSK   NVV P+++V ++GADT+R++ +F +P +  I WS+E 
Sbjct  594  SFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEG  653

Query  657  VDGLFRFLARVWRIYFARQACFDASDaalaeaagealelrrrthrtvkrvtEGLEADLKF  716
            ++G  +FL RV R+  +++   + S+A           +  +              ++KF
Sbjct  654  LEGSRKFLDRVYRLITTKEITEENSGALDKVYNETVKAVTEQV------------DQMKF  701

Query  717  NTSIAALMELVNALYAFEPASEPDRAAVREALLALSTLLAPFAPHVAEELWHEVMGPAAR  776
            NT+IA LM        F  A++ +     +   ++  L+APFAPH++EELW+ + +++  
Sbjct  702  NTAIAQLM-------VFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGES  754

Query  777  DRLVADAPWPAFDPALIVADTVTIAVQVNGKLRGEVQapaaageaevralaeaDEKVKVH  836
               ++  PWP++D + +V + V I VQ++GK+++ +  +   +  E++ +A A+EKV+ +
Sbjct  755  ---ISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAE  811

Query  837  LAGKTVRKVVFVPKRLVNFVV  857
            +AGK + KV+ VP++LVN+V+
Sbjct  812  IAGKDIIKVIAVPNKLVNIVI  832

1304) leuS in NC_008817


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  534 bits (2017),  Expect = 7e-153, Method: Compositional matrix adjust.
 Identities = 352/857 (42%), Positives = 550/857 (65%), Gaps = 35/857 (4%)

Query  17   NLYKPCEIENKWQEIWDKENLYKTDDKSSKKEKFYALSMFPYPSG-NLHMGHVRNYVITD  75
             +Y    IE KWQ +W  ++ +KT+  +SK  KFYAL MFPYPSG  LH+GH   Y  TD
Sbjct  2    TFYDHTAIEPKWQAFWADNHTFKTGTDASK-PKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  76   LIARFQRFQGKSLLHPMGWDAFGLPAENAAIERGINPNDWTKKNIAHMKSQLKLLGLSVD  135
            +++RF+R QG ++LHPMGWDAFGLPAE+ A++ G +P + T  NIA+ K Q++ LG+S D
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  136  WDKEFATCDENYYLWTQFLFLELHKSGLVYQKESEVNWDPIDNTVLANEQVDSEGKSWRS  195
            WD+E  T D NYY WTQ +F  L   GL Y+ E  VNW     T +ANE+V ++G S R+
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  196  GAKVEKKLLTQWFLKITNYTEELLQDLEKLSEWPERVKIMQENWIGKSKGANIIFKINEF  255
            G  V +K + QW LKIT Y+E LL+DLE + +WPE +K MQ NWIGKS GAN+ FK+++ 
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDT  239

Query  256  ENEKIKVFTTRPDTLFGVTYIAISINNPLINKISDNEILSKLENLK--IYLKKNQDKDQ-  312
            +++ + VFTTRPDTLFG TY  ++ +++L++ I+ ++    + + K    LK +  + + 
Sbjct  240  DKD-FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDL  298

Query  313  --KKIGIPTNLKAINPINSNEIPIWIASYVLDEYGTGAVMGVPAHDQRDFEFAKINFidi  370
               K G+ T   AINP+N++E+P+WIA YVL  YGTGA+M+VPAHD+RD EFAK +F   
Sbjct  299  AKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAK-QFNLD  357

Query  371  kqviikdkdndkSTFKLKNAFTDNGFLINSNNFNGLCNNDAKKQILEQGKINGWAEEEIH  430
               ++ + + + +      AFT++G+ INS+ ++GL +  A  +++E    +G ++E++ 
Sbjct  358  IIPVLEGGNVEEA------AFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVT  411

Query  431  YRLRDWLISRQRYWGCPIPIIKCNNCGSIPVNKKNLPVKLP--KEIEISSNKINSLGSYK  488
            YRLRDWL+SRQRYWG PIPII  ++  S +V   +LP+ LP  K+I  S+   ++L++  
Sbjct  412  YRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVT  471

Query  489  DWVKTTCPKCGNLASRETDTMDTFMCSSWYFLRYPSSKCKTKPFEKDNVNKWLPVDQYVG  548
            DW+  T    G  + RET+TM     SSWY+LRY  +    K  + + +++WLPVD YVG
Sbjct  472  DWLEVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVG  530

Query  549  GVEHAILHLLYARFLTKALRDNNLFDIDEPFKKLLTQGMVQAAAYKNTKTGKYISPKDIK  608
            G EHA+LHLLYARF  K L D  +    EPF+KL+ QGM+ +++Y++++ +   + K  K
Sbjct  531  GAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEK  590

Query  609  DFNNPTDPNDDSKLEVLFEKMSKSKYNGIDPESVIKKYGADTARMFILFKAPPEKDLEWG  668
               +  + + +  LE    KMSKS  N ++P+ V+ +YGADT R++ +F +P +  + W+
Sbjct  591  RDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWS  650

Query  669  DSDVEGQYRFLCRIWKLFLDYRNNESWDNQKNYNREKENSLTKSINIAIKEISNDIKNNQ  728
            + ++EG  +FL R+ +L+            K+   E+  +L K  N ++K +++++ + +
Sbjct  651  EEGLEGSRKFLDRVYRLI----------TTKEITEENSGALDKVYNETVKAVTEQVDQMK  700

Query  729  FNTAISELMKFYNSLSSSMIYVNKDLRKDAFKKFCILLAPFAPHIAEEIWN-LIGYQKSV  787
            FNTAI++LM F N+ +      +  L  D  K F  L+APFAPH++EE+W+ L +   S+
Sbjct  701  FNTAIAQLMVFVNAANK-----EDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESI  755

Query  788  HLERWPIFNEDALKEDCYELVIQINGKVRDKINVGIDISEDQIKQKTLTRPNVRKWIDQK  847
                WP ++E  L E+  E+V+QI+GKV+ K+ V+ D+S +++++ +L+  +V+  I  K
Sbjct  756  SYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGK  815

Query  848  TIRKIIIVKGKIMNIVV  864
             I K+I V  K++NIV+
Sbjct  816  DIIKVIAVPNKLVNIVI  832

1305) leuS in NC_017730


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  534 bits (2017),  Expect = 8e-153, Method: Compositional matrix adjust.
 Identities = 351/742 (48%), Positives = 509/742 (69%), Gaps = 68/742 (9%)

Query  231  LVYRSHSMVNWCPGLGTVLANEEVTADGRSERGNFPVFRRNLSQWMMRITAYSDRLIDDL  290
            L Y ++  VNW   LGT +ANEEV +DG SERG +PV R+ + QWM++ITAY++RL++DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  291  DALDWPDKVKSMQRNWIGRSRGAEVDFDV--LGHTITVFTTRPDTLFGASYMVLAPEHEL  348
            + +DWP+ +K MQRNWIG+S GA+V F V   +  +TVFTTRPDTLFGA+Y VLAPEH L
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  349  VDALVAAGTNSYDGVDPRWTFEQSCPADAVKAYRASIAAKSDLERQE-NKEKTGVYLGVN  407
            VDA+ +++                  A+AV  Y+   + KSDL R +  KEKTGV  G  
Sbjct  268  VDAITTSD-----------------QAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSY  310

Query  408  AVNPVNGESIPVFIGDYVLTGYGTGAIMAVPAHDTRDYEFATEFGLPIREVVAGGNVAEE  467
            A+NPVNG  +PV I+DYVL++YGTGAIMAVPAHD RD EFA +F L I  V+ GGNV E 
Sbjct  311  AINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEA  370

Query  468  AYTESGVAVNSANDEGLDINGLDKQEAIARVIEWLVDKQKGSEKIQYKLRDWLFARQRYW  527
            A+TE G+ +NS       ++GLDK  AIA+++EWL     G+E++ Y+LRDWLF+RQRYW
Sbjct  371  AFTEDGLHINSDF-----LDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYW  425

Query  528  GEPFPVVYDADGVAHALPESMLPVELPEVEDYKPVSFDPDDADSEPQPLLAKATEWTQVE  587
            GEP+P++   DG + A+PES LP+ LP   D +P         +  ++ LA+ T+W +V 
Sbjct  426  GEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTDWLEVT  477

Query  588  LDLGDGLKTYTRDTNVMPQWAGSSWYQLRYIDPTNNKQFCDIENERYWTGPRGENdlggv  647
             +  DG+K   R+TN MPQWAGSSWY LRYIDP N  ++ D E  + W           V
Sbjct  478  RE--DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLP---------V  525

Query  648  dlyvggvEHAVLHLLYSRFWHKVLFDLGYVTSGEPYRRLFNQGYIQAFAYTDSRGVYVPA  707
            D+YVGG EHAVLHLLY+RFWHKVL+DLG V + EP+++LFNQG I + +Y DSRG  V++
Sbjct  526  DIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVAT  585

Query  708  AEVEEKDGKFFY--QGEEVNQEYGKMGKSLKNAVAPDEICSDFGADTLRVYEMAMGPLDT  765
              VE +DG FF    GEE++Q  +KM+KSLKN V PD++  ++GADTLRVYEM MGPLD+
Sbjct  586  DKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  766  SRPWATKDVIGAHRFLQRLWRLVVSEDDGSVVVTDAGLADDDLKQLHRTIAGMRDDYEGL  825
            S +W+  ++ G+++FL+R+ RL+ + +   +   ++G  D   K  + T+ ++ ++ + +
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLITTKE---ITEENSGALD---KVYNETVKAVTEQVDQM  699

Query  826  RINTVVAKAIEYVNYLTK------NYAKGAPRAAVEPLVIMVAPVAPHIAEELWKRL-GH  878
            ++NT +A+ + +VN   K      +YAKG        +V ++AP APH++EELW+ L + 
Sbjct  700  KFNTAIAQLMVFVNAANKEDKLFSDYAKG--------FVQLIAPFAPHLGEELWQALTAS  751

Query  879  EETITFVAFPDYDEKWLVDDEVEMPIQINGKVRARIMVPADATQDQIVEIALAEPTVQSH  938
             E+I++V+ P YDE  LV+++VE+ +QI+GKV+A+++V+ D +++++ E+ALA+  VQ++
Sbjct  752  GESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAE  811

Query  939  LEGKNLFKQIVVPGRMVNLVIK  960
            + GK+++K I VP ++VN+VIK
Sbjct  812  IAGKDIIKVIAVPNKLVNIVIK  833


 Score =  141 bits (520),  Expect = 2e-34, Method: Compositional matrix adjust.
 Identities = 81/149 (55%), Positives = 106/149 (72%), Gaps = 10/149 (6%)

Query  28   GDIERTWQQFWIDNGTFNAPNPVGDLAVAGQELPEDKLFVQDMFPYPSGAGLHVGHPLGY  87
              IE  WQ FW DN TF++          G + +  K++  DMFPYPSGAGLHVGHP GY
Sbjct  7    TAIEPKWQAFWADNHTFKT----------GTDASKPKFYALDMFPYPSGAGLHVGHPEGY  56

Query  88   IATDVFARFNRMLGKNVLHTLGYDAFGLPAEQYAIQTGTHPRATTMSNIANMQRQLSALG  147
             ATD+++RF+R  G NVLH +G DAFGLPAEQYA++TG +P   T  NIAN +RQ++ALG
Sbjct  57   TATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALG  116

Query  148  LGHDPRRSVATTDPEFYKWTQWIFLQIFN  176
            ++ D  R V TTDP++YKWTQWIF ++++
Sbjct  117  FSYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1306) Tmath_0360 in NC_014209


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  534 bits (2016),  Expect = 8e-153, Method: Compositional matrix adjust.
 Identities = 379/849 (45%), Positives = 544/849 (65%), Gaps = 59/849 (6%)

Query  5    VDVDRKWQKKWEETKLYKFNPENADKKLYCLEMFSYPSGAKLHVGHWYNYGPTDSWARMK  64
              ++ KWQ  W +   +K   + +  K+Y L+MF+YPSGA LHVGH   Y +TD  +R K
Sbjct  7    TAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSRFK  66

Query  65   RMQGYEVFHPMGFDAFGLPAENYAIKTGIHPYDSTMENIRTMEKQLKEMGATFDWDYEVI  124
            R QG +V+HPMG DAFGLPAE+YA+ TG +P + T ENI    +Q++ +G ++DWD EV 
Sbjct  67   RAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDREVN  126

Query  125  TCLPEYYKWTQWIFLKLFEAGLAYRKKAPVNWCPSCQTVLANEQVI-DGKCERCGTEVTK  183
            T  P+YYKWTQWIF KL+E GLAY    PVNW     T +ANE+V+ DG  ER G  V +
Sbjct  127  TTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVR  186

Query  184  KDLTQWFFKITAYAeellekldeldWPEKTKIMQINWIGKSDGAEIEFKVAGKDLTFKVF  243
            K + QW +KITAYAE LLE L+E+DWPE  K MQ NWIGKS GA++ FKV + D  F VF
Sbjct  187  KPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVF  246

Query  244  TTRADTLYGATYVVIAPEHEIVDLITTEEYKQAVEEYKEYARKQSEIERLSTEKEKTGVF  303
            TTR+DTL+GATY V+APEH +VD ITT +  +AV +YK  A  +S++ R    KEKTGV 
Sbjct  247  TTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVW  306

Query  304  TGAYAIHPLTGEKLPIWIADYVLATYGTGCVMAVPAHDERDYEFATKYNLPIKRVIKGIG  363
            TG+YAI+P+ G  +P+WIADYVLA+YGTG +MAVPAHDERD EFA ++NL I  V+ G G
Sbjct  307  TGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEG-G  365

Query  364  DIDDSLPFVEYGELVDSGEFTGLKSEKARIKIVEKLKQEGRAEFKVNYRLRDWLVSRQRY  423
            +++++ +F E G  ++S+ + GL    A  K+VE L  EG ++ +V YRLRDWL SRQRY
Sbjct  366  NVEEA-AFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRY  424

Query  424  WGAPIPVIH--CERCGIvpvpeedlpvllpYDVEFAPTGESPLKKHEGFMNVTCPKCGGK  481
            WG PIP+IH        VP +E  L + +  D+  + TGESPL +  + ++VT    G K
Sbjct  425  WGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED-GVK  483

Query  482  ALRDPDTLDTFVDSSWYFLRYPDNKNDKEPFNKEWINKMLPVDKYVGGAEHATMHLLYAR  541
            + R+ +T+    +SSWY+LRY D  N     + E +++ LPVD YVGGAEHA +HLLYAR
Sbjct  484  GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYAR  543

Query  542  FVTKALRDLGYLDFDEPFKSLVHQGTILGP------------------------------  571
            F  K L DLG +   EPF+ L +QG ILG                               
Sbjct  544  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEE  603

Query  572  ---DGSRMSKSKGNVISPDEYIKEYGSDVFRLYLMFGFAYSEGGPWNDDGIKAISRFVNR  628
                 ++MSKS  NV++PD+ + +YG+D +R+Y MF  +   + +W+++G+ +  +F++R
Sbjct  604  LEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR  663

Query  629  VERFIDKFIETRNNPGKTKDEMGKDENELNYVRHYAIKSVTEDAERFQFNTAIARIMELV  688
            V R+I            TK+    +   L+ V + ++K+VTE+ ++ +FNTAIA++M +V
Sbjct  664  VYRLI-----------TTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFV  712

Query  689  NALYKYDTDVEVKNIEFYEDVVADLIRLLAPFAPHFSEEMWEKLGYEYSVFN-QKWPKWD  747
            NA          K+  ++ D   ++++L+APFAPH++EE+W+ L      ++   WP  D
Sbjct  713  NA--------ANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYD  764

Query  748  EKALQRDVVEIAVQVNGKVRGRLEVPSNAPDEEVQRIALSDDKIKSYLDGKEikkvivvk  807
            E  L  + VEI VQ++GKV+++L V+ + + EE+Q +AL+++K+++ + GK+I KVI V 
Sbjct  765  ESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVP  824

Query  808  GRLVNIVVK  816
             +LVNIV+K
Sbjct  825  NKLVNIVIK  833

1307) leuS in NC_021191


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  534 bits (2016),  Expect = 9e-153, Method: Compositional matrix adjust.
 Identities = 349/726 (49%), Positives = 499/726 (69%), Gaps = 47/726 (6%)

Query  222  LAYISEAPVNWCPGLGTVLANEEVTPDGRSERGNFPVFQRSLRQWMMRITEYGDRLVEDL  281
            LAY +E PVNW   LGT +ANEEV PDG SERG +PV ++++RQWM++IT Y++RL+EDL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  282  DVLDWPEPVKLMQRNWIGRSRGAHVGFPMDGADT-IEVFTTRPDTLFGATYMVLAPEHGL  340
            + +DWPE++K MQRNWIG+S GA+V F + ++D  + VFTTRPDTLFGATY VLAPEH+L
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  341  VDSIVPAAWPEGTKDAWTGGHATPEaavaayraqaaaKTDEERTADAKVKTGVFTGAYAT  400
            VD+I  +  +E+  D               Y+ QA+ K+D  RT  AK KTGV TG+YA 
Sbjct  268  VDAITTSDQAEAVAD---------------YKRQASLKSDLARTDLAKEKTGVWTGSYAI  312

Query  401  NPVNGARVPVFIADYVLAGYGTGAIMAVPGHDERDWDFAQTFDLPVVRTVQAPDDHEGVW  460
            NPVNG  +PV IADYVLA+YGTGAIMAVP+HDERDW+FA+ F+L ++  +++ + +E+  
Sbjct  313  NPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEAAF  372

Query  461  TGEGVAINSEFLNGLEVTEAKAAMIAWLEEQGHGKGATTYRLRDWLFSRQRYWGEPFPIV  520
            T +G+ INS+FL+GL+ + A A M+ WLE +G G+   TYRLRDWLFSRQRYWGEP+PI+
Sbjct  373  TEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPII  432

Query  521  YDETGLPVALPESMLPVELPEVDDFSPRTFDPDDADSEPETPLSRKKDWVQVELDLGDGP  580
              E G + A+PES LP+ LP   D+ P         +  E+PL+   DW++V  +  DG 
Sbjct  433  HWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTDWLEVTRE--DGV  482

Query  581  KTYTRETNTMPQWAGSCWYELRYLDPHNDKTLVDPQNEAYWMGPRGEGDTGGVDLYVGGV  640
            K   RETNTMPQWAGS WY LRY+DPHN   L D +    W+          VD+YVGG 
Sbjct  483  KG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWL---------PVDIYVGGA  532

Query  641  EHAVLHLLYARFWHKVLFDLGHVSSFEPFRKLYNQGYIQAYAYKDARGFPVQAGDVVERD  700
            EHAVLHLLYARFWHKVL+DLG V++ EPF+KL+NQG I + +Y+D+RG  V ++ V  RD
Sbjct  533  EHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRD  592

Query  701  GKYYLGD--QEVVREYGKMGKSLKNVVTPDEMAQDYGADTFRVYEMAMGPLDASRPWETR  758
            G ++  +  +E+ +  +KM+KSLKNVV PD++ ++YGADT+RVYEM MGPLDAS +W   
Sbjct  593  GSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEE  652

Query  759  AVVGSQRFLQRVWRLVVDEESGAVRVTDDPVDPKTKRVLHRIIDGVRGDMEELRFNTAIA  818
            ++ GS++FL+RV RL+   E     +T++  ++   +V +  + +V  ++++++FNTAIA
Sbjct  653  GLEGSRKFLDRVYRLITTKE-----ITEENSGA-LDKVYNETVKAVTEQVDQMKFNTAIA  706

Query  819  KLIELTNALTPLPTASREAIEPLVLMLSPFAPHLAEELWGKLGHDG-TLAYTGFPVADPA  877
            +L+ + NA         +    +V +++PFAPHL+EELW  L   G +++Y   P  D +
Sbjct  707  QLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDES  766

Query  878  QLVAESITYPVQLNGKVRGRVEVAPEAGEDEVR--TaalaavaealaGREPRKVIVVKGR  935
            +LV + +   VQ++GKV++++ VA + + +E++  + A   V   +AG++  KVI V  +
Sbjct  767  KLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNK  826

Query  936  LVSVVI  941
            LV++VI
Sbjct  827  LVNIVI  832


 Score =  142 bits (523),  Expect = 9e-35, Method: Compositional matrix adjust.
 Identities = 78/151 (52%), Positives = 103/151 (69%), Gaps = 11/151 (7%)

Query  23   NEIEPRWQEFWSQHGTFHAPNPVGELADPEHPRAGAPKLHVQDMFPYPSGEGLHVGHPLG  82
              IEP+WQ FW+++ TF +              A+ PK+   DMFPYPSG GLHVGHP G
Sbjct  7    TAIEPKWQAFWADNHTFKTGTD-----------ASKPKFYALDMFPYPSGAGLHVGHPEG  55

Query  83   YIGTDCYTRYKRMTGFNVLHPMGFDSFGLPAEQYAVQTGTHPATTTAKNVERYRLQLRKL  142
            Y +TD  +R+KR  G NVLHPMG D+FGLPAEQYA++TG +PA  TA N+  ++ Q+  L
Sbjct  56   YTATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINAL  115

Query  143  GLAYDERRTVATTDPAYYRWTQWIFLQIFNS  173
            G++YD  R V TTDP YY+WTQWIF ++++ 
Sbjct  116  GFSYDWDREVNTTDPNYYKWTQWIFTKLYEK  146

1308) Thit_0284 in NC_013921


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  534 bits (2015),  Expect = 9e-153, Method: Compositional matrix adjust.
 Identities = 377/849 (45%), Positives = 543/849 (64%), Gaps = 59/849 (6%)

Query  5    VDVDRKWQKRWEETKLYKFNPENVDKKLYCLEMFSYPSGAKLHVGHWYNYGPTDSWARMK  64
              ++ KWQ  W +   +K   +    K+Y L+MF+YPSGA LHVGH   Y +TD  +R K
Sbjct  7    TAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSRFK  66

Query  65   RMQGYEVFHPMGFDAFGLPAENYAIKTGIHPYDSTMENIRTMEKQLREMGATFDWDYEVI  124
            R QG +V+HPMG DAFGLPAE+YA+ TG +P + T ENI    +Q+  +G ++DWD EV 
Sbjct  67   RAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDREVN  126

Query  125  TCLPEYYKWTQWIFLKLFEAGLAYRKKAPVNWCPSCQTVLANEQVI-DGKCERCGTEVTK  183
            T  P+YYKWTQWIF KL+E GLAY    PVNW     T +ANE+V+ DG  ER G  V +
Sbjct  127  TTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVR  186

Query  184  KDLTQWFFKITAYAeellekldeldWPEKTKIMQRNWIGKSDGAEIEFKVDGKGLTFKVF  243
            K + QW +KITAYAE LLE L+E+DWPE  K MQRNWIGKS GA++ FKV + +  F VF
Sbjct  187  KPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVF  246

Query  244  TTRADTLYGATYVVIAPEHEIVDLITTEEYKQAVEEYKEYARKQSEIERLSTEKEKTGVF  303
            TTR+DTL+GATY V+APEH +VD ITT +  +AV +YK  A  +S++ R    KEKTGV 
Sbjct  247  TTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVW  306

Query  304  TGAYAIHPLTGEKLPIWIADYVLATYGTGCVMAVPAHDERDYEFATKYNLPIKRVIKGIE  363
            TG+YAI+P+ G  +P+WIADYVLA+YGTG +MAVPAHDERD EFA ++NL I  V+ G  
Sbjct  307  TGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEG-G  365

Query  364  DIDDSLPFVEYGVLKDSGEFTGMKSEEARIKIVEKLKQEGRAEFKVNYRLRDWLVSRQRY  423
            +++++ +F E G+  +S+ + G+    A  K+VE L  EG ++ +V YRLRDWL SRQRY
Sbjct  366  NVEEA-AFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRY  424

Query  424  WGAPIPVIH--CERCGIvpvpeedlpvllpYDVEFAPTGESPLKKHEGFMNVTCPKCGGK  481
            WG PIP+IH        VP +E  L + +  D+  + TGESPL +  + ++VT    G K
Sbjct  425  WGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED-GVK  483

Query  482  ALRDPDTLDTFVDSSWYFLRYPDNKNDKEPFNKEWINKMLPVDKYVGGAEHATMHLLYAR  541
            + R+ +T+    +SSWY+LRY D  N     + E +++ LPVD YVGGAEHA +HLLYAR
Sbjct  484  GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYAR  543

Query  542  FVTKALRDLGYLDFDEPFKSLVHQGTILGP------------------------------  571
            F  K L DLG +   EPF+ L +QG ILG                               
Sbjct  544  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEE  603

Query  572  ---DGSRMSKSKGNVISPDEYIKEYGSDVFRLYLMFGFAYSEGGPWNDDGIKAISRFVNR  628
                 ++MSKS  NV++PD+ + +YG+D +R+Y MF  +   + +W+++G+ +  +F++R
Sbjct  604  LEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR  663

Query  629  VERFIDKFIETRNNPGKTKDEMGKDENELNYVRHYAIKGVTEDAERFQFNTAIARIMELV  688
            V R+I            TK+    +   L+ V + ++K+VTE+ ++ +FNTAIA++M +V
Sbjct  664  VYRLI-----------TTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFV  712

Query  689  NALYKYDTDVEVKNIEFYEDVVADLIRLLAPFAPHFSEEMWEKLGYEYSVFN-QKWPKWD  747
            NA          K+  ++ D   ++++L+APFAPH++EE+W+ L      ++   WP  D
Sbjct  713  NA--------ANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYD  764

Query  748  EKALQKDVVEIAVQVNGKVRGRLEVPSNVPDEEVQRIALSDDKIKSYLDGKEikkvivvk  807
            E  L  + VEI VQ++GKV+++L V+ +++ EE+Q +AL+++K+++ + GK+I KVI V 
Sbjct  765  ESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVP  824

Query  808  GRLVNIVVK  816
             +LVNIV+K
Sbjct  825  NKLVNIVIK  833

1309) A464_624 in NC_021870


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  533 bits (2013),  Expect = 1e-152, Method: Compositional matrix adjust.
 Identities = 359/865 (42%), Positives = 555/865 (65%), Gaps = 46/865 (5%)

Query  5    YRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIA  63
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYAEELLGDLDKLDHWPDTVKTMQRNWIGRSEGVEITFDVKGYDNT  242
            V RK + QW +KITAYAE LL DL+ +D WP+++K MQRNWIG+S G ++TF VK+ D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGATYLAVAAGHPL--SVKAAANNPDLATFIDECR-NTKVAEAEMATME  299
            +TV+TTRPDT+ GATY  +A+ H+L  ++ ++ +   +A +  +   ++ +A +++A  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGVDTGFKAIHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFATKYGLTIKPV  359
            K GV TG  AI+P+ G E+PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L I PV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  360  ILAADGSEPDLSEQALTEKGVLFNSGEFNGLGFEDAFNAIADKLASLGVGERKVNYRLRD  419
            +        ++ E A+TE G+ +NS+ ++GL+   A+  + + L + GVG+ +V YRLRD
Sbjct  362  L-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMVTLEDGTVLPTPDDQLPVILP--EDVVMDGIT-SPIKADPEWAKT  476
            W  SRQRYWG PIP++  EDGT  + P+ +LP++LP   D+   G   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  T-VNGMPALRETDTFDTFMESSWYYARYTCPQYQEGMLDSNAANYWLPVDIYIGGIEHAI  535
            T  +G+ + RET+T      SSWYY RY  P+  E + D +  + WLPVDIY+GG EHA+
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVER  595
            +HLLY RF HK++ D G+V + EP ++L+ QGM+L+ ++      + R  + + D +  R
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEKR  591

Query  596  DEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMT  655
            D  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D +
Sbjct  592  D--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  656  LEWQESGVEGANRFIKRVWKLVYEHTAKGSVAALNVDALSEDQKALRRDVHKTIAKVTDD  715
            + W E G+EG+ +F+ RV +L+   T+K        +   E+  AL +  + T+  VT++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLI---TTK--------EITEENSGALDKVYNETVKAVTEQ  695

Query  716  IGRRQTFNTAIAAIMELMNKLAKAPQESEQDRALMQEALLAVVRMLNPFTPHVCFTLWQA  775
            +++ + FNTAIA +M ++N        ++++  L  +   + V+++ PF+PH+   LWQA
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  776  LEGEGD-IDNAPWPVADDKAMVEESTLVVVQVNGKVRGKITVPVNATEEQVRERAGQEHL  834
            L + G+ I   PWP  D+  +VE+   +VVQ++GKV++K+ V+ + + E+++E A  ++ 
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  835  VAKYLDGVTVRKVIYVPGKLLNLVV  859
            V   + G  + KVI VP KL+N+V+
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVI  832

1310) Smon_0349 in NC_013515


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  533 bits (2013),  Expect = 1e-152, Method: Compositional matrix adjust.
 Identities = 361/874 (42%), Positives = 548/874 (63%), Gaps = 57/874 (6%)

Query  5    YIAKEVEQKWQEIWEKNKVFKTENKVKGKENYYTLEMFAYPSGK-LHAGHLRNYTIGDAI  63
            Y    +E KWQ +W  N  FKT     +K ++Y+L+MF+YPSG  LH GH   YT  D +
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDA-SKPKFYALDMFPYPSGAGLHVGHPEGYTATDIL  62

Query  64   ARYKKMKGFNVLHTFGWDSFGLPAENAAIDNGASPAIWTAQNIGNMKRQLKLMGLSYDWD  123
            +R+K+ +G NVLH  GWD+FGLPAE+ A+D G  PA  TA+NI+N KRQ++ +G+SYDWD
Sbjct  63   SRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWD  122

Query  124  RELATYKKEYYKFNQKFFIEMYKKGLVYKRKSYVNWCPDCNTVLANEQV-EDGKCWRHGK  182
            RE+ T   +YYK  Q +F  +Y KGL Y     VNW  +  T +ANE+V  DG    +G 
Sbjct  123  REVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTS-ERGG  181

Query  183  TSVIQKELSQWYFKITDYAEELLTGHEELKGYWPEQVLAMQKNWIGKSSGTEIIFTLEYD  242
             +V++K + QW +KIT YAE LL + EE+   WPE +  MQ+NWIGKS+G+++ F +   
Sbjct  182  YPVVRKPMRQWMLKITAYAERLLEDLEEVD--WPESIKDMQRNWIGKSTGANVTFKV--K  237

Query  243  GKEIEIPVFTTRVDTIYGVTYISIAPELPLVSEIVLKEKPE-LKSLIDEMINEDKISREA  301
            + + ++ VFTTR DT++G TY  +APE +LV  I   +++E +     +      ++R  
Sbjct  238  DTDKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTD  297

Query  302  QDKEKRGVFTGLYVKHPLTNEMIPVYIANYVLMDYGTGAVMGVPAHDERDFSFAKKYGLN  361
              KEK GV TG Y  +P+    +PV IA+YVL  YGTGA+M+VPAHDERD  FAK++ L+
Sbjct  298  LAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLD  357

Query  362  AKAVIKAKNPEDDFNGNKTFLGKGELINSDEFNGIHNieakekiaeklekigkgHKTVNY  421
              +V+ + N E+      +F   G  INSD ++G+++  A  K+ E LE  G G+  V Y
Sbjct  358  IIPVLEGGNVEEA-----AFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTY  412

Query  422  RLHDWLISRQRYWGTPIPVIYDEDG--NVYLDENLPVELPTDIDF---GVKGNPIETSKT  476
            RL+DWL+SRQRYWG PIP+I  EDG      + +LP+ LP   D+   G   +P+     
Sbjct  413  RLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTD  472

Query  477  FKEVILPNGKKGYRETDTMDTFVDSSWYYLRYLDP-SNENLA---FLKEDADNYTPVDQY  532
              EV   +G KG RET+TM    +SSWYYLRY+DP + E+LA   +LK+      PVD Y
Sbjct  473  WLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQ----WLPVDIY  528

Query  533  IGGIEHAVMHLLYARFFHKVFRDLGYLSTNEPFKRLLTQGMVLDYSYYSNNERRYLHKEE  592
            +GG EHAV+HLLYARF HKV+ DLG ++T+EPF++L+ QGM+L+ S Y ++    +  + 
Sbjct  529  VGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS-YRDSRGALVATDK  587

Query  593  VEIKDGKAFNIKTGEELVSKLEKMSKSKNNGVDPEKIIQEFGADAARIFTLFAAPPEKEL  652
            VE +DG  F++ TGEEL     KMSKS +N V+P+ +++++GAD+ R++ +F +P +  +
Sbjct  588  VEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASI  647

Query  653  EWNANGVVGAYRFINRIYLMVQECLDILIEDYSEIDLSKRSKEDENLQRKTHQTIKRVTD  712
             W+ +G+ G+ +F++R+Y ++            EI       +   L++  ++T+K VT+
Sbjct  648  AWSEEGLEGSRKFLDRVYRLITT---------KEIT----EENSGALDKVYNETVKAVTE  694

Query  713  SMEDNFHFNTAIAGSMELINELTTYKQNVLDVNNKSSESNKVFKESMISLILMMSPFAPH  772
             +++   FNTAIA  M ++N               ++  +K+F +   +++ +++PFAPH
Sbjct  695  QVDQ-MKFNTAIAQLMVFVNA--------------ANKEDKLFSDYAKGFVQLIAPFAPH  739

Query  773  LAEEIWQ-LCKMDGYIFNASWPTYIEELTHVSEITMVVQVNGKVRGEFETNINVSEEEIV  831
            L+EE+WQ L   +  I   +WP+Y E     +++ +VVQ++GKV++ +    ++S EE+ 
Sbjct  740  LGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQ  799

Query  832  KKALSNENVQRNIEGKEIIKTIVVPKKLVNIVVR  865
              AL+NE+VQ +I GK+IIK I VP+KLVNIV++
Sbjct  800  EVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

1311) leuS in NC_020302


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  533 bits (2011),  Expect = 2e-152, Method: Compositional matrix adjust.
 Identities = 358/741 (49%), Positives = 507/741 (69%), Gaps = 62/741 (8%)

Query  217  LVYRSNSTVNWCPGLGTVLANEEVTADGRSERGNFPVFRKNLSQWMMRITAYSDRLIDDL  276
            L Y ++  VNW   LGT +ANEEV +DG SERG +PV RK + QWM++ITAY++RL++DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  277  ELLDWPEKVKSMQRNWIGRSRGAEVNFLAQ--GETITVFTTRPDTLFGATYMVLAPEHEL  334
            E +DWPE +K MQRNWIG+S GA+V F  +  +  +TVFTTRPDTLFGATY VLAPEH L
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  335  VDTLVAGGTGTYDDVDERWTYGRANPAEAVAAYRSDIAAKSDLERQE-NKEKTGVFLGAY  393
            VD++ +                 ++ AEAVA Y+ + + KSDL R +  KEKTGV  G+Y
Sbjct  268  VDAITT-----------------SDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSY  310

Query  394  AINPVNGAEIPVFIADYVLTGYGTGAIMAVPAHDTRDYEFAGVFGLPIREVVSGGNVAEE  453
            AINPVNG E+PV IADYVL++YGTGAIMAVPAHD RD EFA  F L I  V+ GGNV E 
Sbjct  311  AINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEA  370

Query  454  AWTGDGTLVNSVNDQSLDINGLNKAEAIERTIEWLMDSEMGVEKIQYKLRDWLFARQRYW  513
            A T DG  +NS       ++GL+KA AI + +EWL    +G E++ Y+LRDWLF+RQRYW
Sbjct  371  AFTEDGLHINSDF-----LDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYW  425

Query  514  GEPFPVVYDEDGLAHALPDSMLPVELPEVEDYKPVSFDPDDADSEPQPPLAKAREWVEVE  573
            GEP+P++  EDG + A+P+S LP+ LP   D +P         +  ++PLA+  +W+EV 
Sbjct  426  GEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTDWLEVT  477

Query  574  LDLG-EGRQKYYRDTNVMPQWAGSSWYQLRYIDPTNDDQLCNLENERYWTGPRPEKHGAN  632
             + G  GR    R+TN MPQWAGSSWY LRYIDP N ++L + E  + W           
Sbjct  478  REDGVKGR----RETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWL----------  523

Query  633  DPGGVDLYVGGVEHAVLHLLYSRFWHKVLFDLGHVTSKEPYRRLYNQGYIQAYAYTDARG  692
                VD+YVGG EHAVLHLLY+RFWHKVL+DLG V +KEP+++L+NQG I + +Y D+RG
Sbjct  524  ---PVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRG  580

Query  693  VYVPAAEVEERDGRFYF--EGEEVNQEYGKMGKSLKNAVAPDEIAENFGADTLRVYEMSM  750
              V++  VE RDG F+    GEE++Q  +KM+KSLKN V PD++ E++GADTLRVYEM M
Sbjct  581  ALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFM  640

Query  751  GPLDTSRPWATKDVIGAQRFLQRLWRLIVDENTGEVLTTDAALTDEDSKQLHRTVAGVRD  810
            GPLD+S +W+  ++ G+++FL+R+ RLI   +  E     +AL     K  + TV +V +
Sbjct  641  GPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITE--ENSGAL----DKVYNETVKAVTE  694

Query  811  DYTHLRVNTVVAKLIEYVNYLTKTYPDAIPAAAVEPLVIMVAPVAPHIAEELWKRL-GHE  869
            +  +++ NT +A+L+ +VN   K   D + +     +V ++AP APH++EELW+ L +  
Sbjct  695  QVDQMKFNTAIAQLMVFVNAANKE--DKLFSDYAKGFVQLIAPFAPHLGEELWQALTASG  752

Query  870  ETITFAEFPTFDEKWLVDDEIELPVQVNGKVRGRVTVPadaaqddivaaaladekvaaHI  929
            E+I++   P++DE  LV++++E+ VQ++GKV++++ V+ D +++++   ALA+EKV A+I
Sbjct  753  ESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEI  812

Query  930  EGKNVVKQIVVPGRMVNLVVK  950
             GK+++K I VP ++VN+V+K
Sbjct  813  AGKDIIKVIAVPNKLVNIVIK  833


 Score =  138 bits (508),  Expect = 2e-33, Method: Compositional matrix adjust.
 Identities = 76/148 (52%), Positives = 103/148 (70%), Gaps = 11/148 (7%)

Query  20   IERDWQQYWTDNGTFNAPNPVGDLAPESGELLPEDKLFVQDMFPYPSGSGLHVGHPLGYI  79
            IE  WQ +W+DN TF++    +             K++  DMFPYPSG+GLHVGHP GY 
Sbjct  9    IEPKWQAFWADNHTFKTGTDASK-----------PKFYALDMFPYPSGAGLHVGHPEGYT  57

Query  80   ATDVFARFNRMLGKNVLHTLGYDSFGLPAEQYAIQTGTHPRTTTMANIENMRRQLGALGL  139
            ATD+++RF+R  G NVLH +G D+FGLPAEQYA++TG +P   T  NI N +RQ+ ALG+
Sbjct  58   ATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGF  117

Query  140  GHDQRRSVATTDPEFYRWTQWIFLQIYN  167
            + D  R V TTDP++Y+WTQWIF ++Y+
Sbjct  118  SYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1312) leuS in NC_014803


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  533 bits (2012),  Expect = 2e-152, Method: Compositional matrix adjust.
 Identities = 365/870 (42%), Positives = 558/870 (65%), Gaps = 52/870 (5%)

Query  5    YNPQDIESKVQRYWEENQVFKVTEDESKEKYYCLSMFPYPSGR-LHMGHVRNYTIGDVVS  63
            Y+   IE+K Q +W +N+ FK   D SK K+Y L MFPYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RFQRLQGKNVMQPMGWDAFGLPAENAAIKNKTAPAKWTYENIDYMRNQLKQLGFGYDWDR  123
            RF+R QG NV++PMGWDAFGLPAE+ A+     PA  T ENI   + Q++ LGF+YDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EIATCHPEYYKWEQWFFTKLYEKGLVYKKMSTVNWDPVDQTVLANEQVI-DGRGWRSGAV  182
            E+ T +P+YYKW QW+FTKLYEKGL Y     VNW     T +ANE+V+ DG + R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VEQKEIPQWFIKITDYAQellddldkledWPEQVKTMQRNWIGRSEGLDIEFTRTDNNEK  242
            V +K + QW +KIT YA+  L +     DWPE +K MQRNWIG+S G ++ F   D +  
Sbjct  184  VVRKPMRQWMLKITAYAE-RLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  FSVYTTRPDTFMGVTYLAVAGGHPIAQEAAKNNDAIAMFVEECKNTKVAEADMA----TM  298
            F+V+TTRPDT+ G TY  +A  H++ +  + +++A A  V + K      +D+A    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEA--VADYKRQASLKSDLARTDLAK  300

Query  299  EKKGIATGFYATHPLTGEQVPIWVANFVLMHYGSGAVMAVPAHDQRDFEFATAYGLDIKQ  358
            EK G+ TG YA +P+ G ++P+W+A++VL  YG+GA+MAVPAHD+RD EFA  + LDI  
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VIAPAEGSELEVNLSKEAFTEKGVLVNSGEFDGLDFEHAFNAVADKLEALGVGERKVNFR  418
            V+   EG+++E      AFTE G+ +NS+ +DGLD   A+  + + LEA GVG+ +V +R
Sbjct  361  VL---EGGNVE----EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYR  413

Query  419  LRDWGVSRQRYWGSPIPMLSDENGNELAATEDMLPVRLP--EDVVMNGVT-SPIKADPNW  475
            LRDW  SRQRYWG PIP++  E+G   A  E  LP+ LP   D+  +G   SP+    +W
Sbjct  414  LRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDW  473

Query  476  AKTT-VNGVPATHETDTFDTFMESSWYYARYCSPRHDEGMLDPAAANYWLPVNQYIGGIE  534
               T  +GV + +ET+T      SSWYY RY  P++ E + D    + WLPV+ Y+GG E
Sbjct  474  LEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAE  533

Query  535  HAILHLLYSRFFHKLLRDFGLVNSDEPFDRLLCQGMVLAETFYRKDEKGGDIWISPSDVN  594
            HA+LHLLY+RF HK+L D+G+V + EPF++L+ QGM+L+ ++  +D +G       + V 
Sbjct  534  HAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY--RDSRG-------ALVA  584

Query  595  TETDDKGRVTKAWHKDDGEPVFssgmskmsksknngIDPQEVIAQYGADTVRLFMMFTAP  654
            T+  +K R     H + GE +   + +KMSKS +N ++P++V+ QYGADT+R++ MF +P
Sbjct  585  TDKVEK-RDGSFFHVETGEEL-EQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGP  642

Query  655  PEQTLEWSDSGVEGAHRFLKRVWKYAVDVKTVGYQALDKSALTNPQK-VLRRELHKAIAK  713
             + ++ WS+ G+EG+++FL RV           Y+ +    +T+ +   L +  + ++  
Sbjct  643  LDASIAWSEEGLEGSRKFLDRV-----------YRLITTKEITEENSGALDKVYNETVKA  691

Query  714  VSDDVERRQTFNTAIAAIMELSNKLLKAPLSDTQDVaianealealiimlaPITPHLSHQ  773
            V+++V++ + FNTAIA +M + N       +  ++  + ++   +++ ++AP++PHL+++
Sbjct  692  VTEQVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEE  743

Query  774  LWQDLGKGGDILD-AAWPKVDESALVEDEKLIIVQVNGKLRAKLTVAADATQEQVEALAF  832
            LWQ L  +G+ +   +WP  DES LVE++  I+VQ++GK++AKL VA D ++E+++ +A+
Sbjct  744  LWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVAL  803

Query  833  AESNVTKFTDGATIRKVIYVPGKLLNVVAN  862
            A+ +V     G  I KVI VP KL+N+V +
Sbjct  804  ANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

1313) leuS in NC_021291


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  533 bits (2011),  Expect = 2e-152, Method: Compositional matrix adjust.
 Identities = 353/870 (41%), Positives = 559/870 (65%), Gaps = 51/870 (5%)

Query  5    YNPATIEQAAQSYWDAEGTFQVTEDPAREKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIS  63
            Y+ ++IE   Q++W  + TF+   D+++ K+Y L M+PYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMQGRNVLQPMGWDAFGLPAENAAIKRGVPPAKWTYENIDHMRRQLQRMGYGYDWTR  123
            R++R QG+NVL+PMGWDAFGLPAE+ A+  G  PA  T ENI + +RQ++ +G++YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVTTCDSDYYRWEQLMFTQLLEKGLVYRARAVVNWDPVDQTVLANEQVV-DGRGWRSGAP  182
            EV T D++YY+W Q +FT+L EKGL Y A   VNW     T +ANE+V+ DG + R+G P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERREIPQWFIRITEYADELLDGLEALPGWPDAVKTMQRNWIGRSEGVELDFALAEGGEP  242
            V R+ + QW ++IT YA+ LL++LE + +WP+++K MQRNWIG+S G ++ F + + +  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LRVYTTRPDTLYGATY--MavaadhplavaaGERDPALADFLEEIR-KGAVTEEAMEKLE  299
            + V+TTRPDTL+GATY  +A       A++++++  A+AD+  +   K+ ++   + K E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK-E  301

Query  300  KKGMPLGVEAVNPLSGERIPVWVANFVLMGYGTGAIMAVPAHDARDHEFATRYGLPIRQA  359
            K G+  G  A+NP++G  +PVW+A++VL +YGTGAIMAVPAHD RD EFA ++ L I   
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  360  VGPADGTSVDVQAEPWTAKDDLVTVNAGDFTGMDFPTAFESIAQFLENQGIGERRVNYRL  419
            +   +G +V+  A      +D + +N++ + G+D ++A+  + + LE +G+G+  V YRL
Sbjct  362  L---EGGNVEEAA----FTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRL  414

Query  420  RDWGVSRQRYWGCPIPVIHCPDCGAVPVPAEDLPVTLP--EQVTFTGL-QSPLKTDEAWR  476
            RDW  SRQRYWG PIP+IH  D  + +VP  +LP+ LP   ++  +G  +SPL     W 
Sbjct  415  RDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWL  474

Query  477  QVECPRCGVAAERETDTFDTFVESSWYYARYCTPDADAMLDDRA--NYWLPVNQYIGGIE  534
            +V     GV + RET+T      SSWYY RY  P+    L D    + WLPV+ Y+GG E
Sbjct  475  EV-TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAE  533

Query  535  HAVMHLLYFRFWHKLMRDLGWVTSDEPATNLLCQGMVLAEAYYHDSEAGGREWIAPAEVA  594
            HAV+HLLY RFWHK++ DLG V + EP  +L+ QGM+L+ + Y+DS ++    + +++  
Sbjct  534  HAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS-YRDSRGA----LVATDKV  588

Query  595  VERDGKGRVVSARRAHDGVEVVSTGWTTMSKSKNNGEDPESLVDRFGADTLRLFTMFAAP  654
              RDG     S  + + G E+  +  + MSKS +N  +P+ +V+++GADTLR++ MF +P
Sbjct  589  EKRDG-----SFFHVETGEELEQAP-AKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGP  642

Query  655  PDQALEWQDSGVEGASRFLRRVYGLVRDHVAAGTIPAPAPSQLDEEGIALRRKLHETIRK  714
             D ++ W + G+EG+ +FL RVY L+     +           +E++ AL +  +ET++ 
Sbjct  643  LDASIAWSEEGLEGSRKFLDRVYRLITTKEIT-----------EENSGALDKVYNETVKA  691

Query  715  VSDDVGRRYTFNTAVAAVMELCNALGRYEATDANARGLRQEALEAVVLMLQPITPHLSHA  774
            V+++V++   FNTA+A +M + NA  +          L  +   + V ++ P++PHL++ 
Sbjct  692  VTEQVDQM-KFNTAIAQLMVFVNAANK-------EDKLFSDYAKGFVQLIAPFAPHLGEE  743

Query  775  LWQALGQPGAAVD-QAWPAVDESALARDEVELVVQVNGKLRSRLQVAADASEESIRAAAL  833
            LWQAL  +G ++   +WP+ DES L  ++VE+VVQ++GK++++L VA D S E ++  AL
Sbjct  744  LWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVAL  803

Query  834  VDPNVERFIEALTVRKVIVVPGRLVNVVAN  863
             + +V+  I +  + KVI VP +LVN+V +
Sbjct  804  ANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

1314) ECL_03054 in NC_014121


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  533 bits (2012),  Expect = 2e-152, Method: Compositional matrix adjust.
 Identities = 353/866 (41%), Positives = 547/866 (64%), Gaps = 48/866 (5%)

Query  5    YRPEEIESKVQQHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIA  63
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADELLNDLDTLDHWPDTVKTMQLNWIGRSEGVEITFNVENYDQT  242
            V RK + QW +KITAYA+ LL+DL+ +D WP+++K MQ NWIG+S G ++TF+V + D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGATYLAVAAGHPLAQKAAENNPELAIFIDECRNTKVAEADMA----TM  298
            +TV+TTRPDT+ GATY  +A+ H+L +  + ++   A  + + +      +D+A    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEA--VADYKRQASLKSDLARTDLAK  300

Query  299  EKKGVATGFYAKHPLTGEAIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFATKYNLPIKA  358
            EK GV TG YA +P+ G  +PVW A++VL  YGTGA+MAVP+HD+RD EFA ++NL I +
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VILAADGSEPDLSEQALTEKGTLFNSGEFSGLSFEEGFNAIADKLASLGVGERKVNYRLR  418
            V+ +++  E+ ++E++L  ++ +++     GL    ++  + + L + GVG+ +V YRLR
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLD-----GLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  419  DWGVSRQRYWGAPIPMVTLEDGTVMPTPEDQLPVILP--EDVVMDGIT-SPIKADPEWAK  475
            DW  SRQRYWG PIP++  EDGT  + PE +LP++LP   D+   G   SP+    +W  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  476  TT-VNGQPALRETDTFDTFMESSWYYARYTCPQYQEGMLDSDAANYWLPVDIYIGGIEHA  534
             T  +G  + RET+T      SSWYY RY  P+  E + D +  + WLPVDIY+GG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  535  IMHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGANGERNWVSPVDAIVE  594
            ++HLLY RF HK++ D G+V + EP ++L+ QGM+L+ +  Y ++ G    + + D +  
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS--YRDSRGA---LVATDKVEK  590

Query  595  RDEKGRIVKAKDAEGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADM  654
            RD  G +     +E  E    + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D 
Sbjct  591  RD--GSFFHVETGEELE---QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  655  TLEWQESGVEGANRFLKRVWKLVYEHTAQGDAPALNVAALTEDQQALRRDVHKTIAKVTD  714
            ++ W E G+EG+ +FL RV +L+       + ++           AL +  + T+  VT+
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLITTKEITEENSG-----------ALDKVYNETVKAVTE  694

Query  715  DIGRRQTFNTAIAAIMELMNKLAKAPQEGEQDRALMREALLAVVRMLNPFTPHVSFTLWQ  774
            ++++ + FNTAIA +M ++N        ++++  L  +   + V+++ PF+PH++  LWQ
Sbjct  695  QVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  775  ELKGEGD-IDNAPWPVADESAMVENTTLVVVQVNGKVRGKITVAVDATEEQVRERAGQEH  833
             L + G+ I   PWP  DES +VEN   +VVQ++GKV++K+ VA D + E+++E A  ++
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  834  LVAKYLEGVTVRKVIYVPGKLLNLVV  859
             V   + G  + KVI VP KL+N+V+
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVI  832

1315) leuS in NC_018405


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  533 bits (2013),  Expect = 2e-152, Method: Compositional matrix adjust.
 Identities = 355/866 (41%), Positives = 552/866 (64%), Gaps = 48/866 (5%)

Query  5    YRPEEIESKVQQHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIA  63
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKTMQRNWIGRSEGVEITFNVESYDQT  242
            V RK + QW +KITAYA+ LL+DL+ +D WP+++K MQRNWIG+S G ++TF+V   D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGATYLAVAAGHPLAQ--KAAENNPELATFIDECR-NTKVAEADMATME  299
            +TV+TTRPDT+ GATY  +A+ H+L +   ++++   +A +  +   ++ +A +D+A  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGVDTGFKAIHPLTGEAIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFATKYGLTIKPV  359
            K GV TG  AI+P+ G  +PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L I PV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  360  ILAADGSEPDLSEQALTEKGTLFNSGEFSGLSFEEGFNAIADKLASLGVGERKVNFRLRD  419
            + +++  E+ ++E++L  ++ +++     GL    ++  + + L + GVG+ +V +RLRD
Sbjct  362  LEGGNVEEAAFTEDGLHINSDFLD-----GLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMVTLEDGTVMPTPEDQLPVILP--EDVVMDGIT-SPIKADPEWAKT  476
            W  SRQRYWG PIP++  EDGT  + PE +LP++LP   D+   G   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  T-VNGQPALRETDTFDTFMESSWYYARYTCPQYQEGMLDSDAANYWLPVDIYIGGIEHAI  535
            T  +G  + RET+T      SSWYY RY  P+  E + D +  + WLPVDIY+GG EHA+
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGANGERNWVSPVDAIVER  595
            +HLLY RF HK++ D G+V + EP ++L+ QGM+L+ +  Y ++ G    + + D +  R
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS--YRDSRGA---LVATDKVEKR  591

Query  596  DEKGRIVKATDAEGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMT  655
            D  G +     +E  E    + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D +
Sbjct  592  D--GSFFHVETGEELE---QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  656  LEWQESGVEGANRFLKRVWKLVYEHTAQGDAPALNAAALTEDQQ-ALRRDVHKTIAKVTD  714
            + W E G+EG+ +FL RV +L+             +  +TE++  AL +  + T+  VT+
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLI------------TTKEITEENSGALDKVYNETVKAVTE  694

Query  715  DIGRRQTFNTAIAAIMELMNKLAKAPQDGEQDRALMREALLAVVRMLNPFTPHVSFTLWQ  774
            ++++ + FNTAIA +M ++N        ++++  L  +   + V+++ PF+PH++  LWQ
Sbjct  695  QVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  775  ELKGEGD-IDNAPWPVADEAAMVENTTLVVVQVNGKVRGKITVAVDATEEQVRERAGQEP  833
             L + G+ I   PWP  DE+ +VEN   +VVQ++GKV++K+ VA D + E+++E A  + 
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  834  LVAKYLEGVTVRKVIYVPGKLLNLVV  859
             V   + G  + KVI VP KL+N+V+
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVI  832

1316) leuS in NC_010694


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  533 bits (2011),  Expect = 2e-152, Method: Compositional matrix adjust.
 Identities = 350/866 (41%), Positives = 546/866 (64%), Gaps = 48/866 (5%)

Query  5    YRPEEIESNVQQHWDEKQTFKVTEDEGKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIS  63
            Y    IE++ Q  W +++TFK   D +K K+Y L M+PYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYANIDYMKNQLKLLGFGYDWNR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T  NI   K Q++ LGF+YDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCQPEYYRWEQWFFTKLYEKGLVYKKTSAVNWCPHDMTVLANEQVI-DGCCWRCDSK  182
            E+ T +P+YY+W QW+FTKLYEKGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFVKITDYADELLNDLDKLESWPEQVKTMQRNWIGRSEGVEIEFTVLNSEEK  242
            V RK + QW +KIT YA+ LL+DL+ ++ WPE +K MQRNWIG+S G ++ F V +++  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LSVYTTRPDTFMGVTYlavaaghplaaqaalnnpalaDFIAECRNTKVAEADMA----TM  298
            ++V+TTRPDT+ G TY     +   A   A+  +  A+ +A+ +      +D+A    + 
Sbjct  243  FTVFTTRPDTLFGATY--AVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  299  EKKGMATGLFAAHPLTGEKVPVWVANFVLMEYGTGAVMAVPGHDQRDWEFASKYSLPIKP  358
            EK G+ TG +A +P+ G  +PVW+A++VL  YGTGA+MAVP+HD+RDWEFA +++L I P
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VILAADGSEPDLSGSAMTEKGTLFNSGEFDGLSHEAGFDAIAAKLADKGVGERKVNYRLR  418
            V+ +++  E+ ++  ++  ++ +     +DGL   +++  +   L   GVG+ +V YRLR
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDF-----LDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  419  DWGVSRQRYWGAPIPMVTLEDGTVMPTPEDQLPVILP--EDVVMDGIT-SPIKADAEWAK  475
            DW  SRQRYWG PIP++  EDGT  + PE +LP++LP   D+   G   SP+   ++W  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  476  TT-VNGQPALRETDTFDTFMESSWYYARYTCPNYDKGMLDPAAANYWLPVDQYVGGIEHA  534
             T  +G  + RET+T      SSWYY RY  P+    + D    + WLPVD YVGG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  535  IMHLLYFRFFHKLLRDTGLVNSDEPAKRLLCQGMVLADAFYFTGSNGERNWVSPTDVSVE  594
            ++HLLY RF HK+L D G+V + EP ++L+ QGM+L+ ++      + R     + V+ +
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRG----ALVATD  586

Query  595  RDEKGRITKATDNDGNELIYAGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPAEM  654
            + EK   +    + G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P + 
Sbjct  587  KVEKRDGSFFHVETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  655  TLEWQESGVEGANRFLKRVWRLAFEHTEKGPTVALDLDALNDEQKALRRDLHKTISKVSD  714
            ++ W E G+EG+ +FL RV RL    T K  T        +++  AL +  + T+  V++
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLI---TTKEIT--------EENSGALDKVYNETVKAVTE  694

Query  715  DIGRRQTFNTAIAAIMELMNKLARAPQETEQDRALMQEALLAVVRMLNPFTPHASFVLWQ  774
            ++++ + FNTAIA +M ++N        ++++  L  +   + V+++ PF+PH +  LWQ
Sbjct  695  QVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  775  ALGGAGE-IDNAPWPQAEEAAMVEDSLLVVVQVNGKVRGKITVAADATQEQVQARAAQEH  833
            AL ++GE I   PWP  +E+ +VE+ + +VVQ++GKV++K+ VA D ++E++Q  A  ++
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  834  LVAKYLDGVTIRKVIFVPGKLLNLVV  859
             V   + G  I KVI VP KL+N+V+
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVI  832

1317) leuS in NC_009566


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  533 bits (2010),  Expect = 3e-152, Method: Compositional matrix adjust.
 Identities = 359/866 (42%), Positives = 556/866 (65%), Gaps = 46/866 (5%)

Query  5    YRPDMIEPKVQQYWAENKVFKAIKDESKEKYYCLSMFPYPSGR-LHMGHVRNYTIGDVIS  63
            Y    IEPK Q +WA+N  FK+  D SK K+Y L MFPYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPFGWDAFGLPAEGAAIKNKTAPAKWTYENIAYMKKQLQLLGFGFDWDR  123
            R++R  G NVL+P GWDAFGLPAE  A+     PA  T ENIA  K+Q++ LGF++DWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EIATCKPDYYKWEQWFFTELYKKGLVYKKTSTVNWCPNDETVLANEQV-HEGCCWRCDTP  182
            E+ T  P+YYKW QW+FT LY KGL Y     VNW  +  T +ANE+V  +G   R + P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VEQKEIPQWFIKITDYAEQLLGGLDTLPQWPDMVKTMQRNWIGRSEGVEITFDVANTNEK  242
            V +K + QW +KIT YAE+LL +L+ + +WP+ +K MQRNWIG+S G ++TF V +T+  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  VAVYTTRPDTFYGVSY--LGIaaahplaslaaQNNSELAAFIQEAK-NAKVAEADLATME  299
             +V+TTRPDT++G +Y  L+   A   A  ++++   +A + ++A  ++ +A +DLA  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGMATGLFAIHPLTGEKLPIWVANFVLMHYGTGAVMAVPAHDQRDFEFAQKYGLQIKQV  359
            K G+ TG +AI+P+ G  +P+W+A++VL  YGTGA+MAVPAHD+RD EFA+++ L+I  V
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  360  IEPIADEEIDLTKQAFTEHGKLVNSAEFDGKDFDGAFNGIADKLEKLGVGKRQVNYRLRD  419
            +E    EE      AFTE+G  +NS  +DG D  +A+  + + LE  GVG+ +V YRLRD
Sbjct  362  LEGGNVEE-----AAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMLTLENGDVVPAPMEDLPIILP--EDVVMDGV-KSPIKADLNWAKT  476
            W  SRQRYWG PIP++  E+G   + P  +LP++LP   D+   G   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  TL-NGAPALKETDTFDTFMESSWYYARYTCPQYQNGMLDAEEANYWLPVDQYIGGIEHAT  535
            T  +G  + +ET+T      SSWYY RY  P+  + + D E  + WLPVD Y+GG EHA 
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLLYFRFFHKLLRDAGFVTSDEPADKLLCQGMVLADAFYYTSPTNERIWVSPTQVTLER  595
            +HLLY RF HK+L D G V + EP +KL+ QGM+L+ ++      + R     + V+ ++
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSR----GALVATDK  587

Query  596  DEKGRIIKATDPEGRELVHSGMTKMSKSKNNGIDPQEMVEKYGADTVRLFMMFASPAEMT  655
             EK R     + E  E ++ + +KMSKS +N ++P+++VE+YGADT+R++ MF +P + +
Sbjct  588  VEK-RDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  656  LEWQESGVEGAKRFLGRVWNLVYQYQQNPAKTSLDLTALSAEQKVLRREVHKTIAKVSDD  715
            + W E G+EG+++FL+RV  L+         T+ ++T    +   L +  + T+  V+++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLI---------TTKEITE--ENSGALDKVYNETVKAVTEQ  695

Query  716  IGRRQTFNTAIAAVMELMNKLTKASLDSEQDRAVMAEALSAVVRMLYPITPHICFELWQA  775
            +++ + FNTAIA +M ++N        ++++  + ++   + V+++ P++PH+  ELWQA
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  776  L-GNESAIDTAEWVKADEAAMVEDEKLIVVQVNGKVRGKVTVAADADEDTVKTIAFADEN  834
            L ++  +I    W   DE+ +VE++  IVVQ++GKV++K+ VA D   + ++ +A+A+E+
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  835  VKKFIDNQHIVKVIYVVGKLLNVVVK  860
            V+  I  ++I+KVI V  KL+N+V+K
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVIK  833

1318) leuS in NC_017452


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  533 bits (2010),  Expect = 3e-152, Method: Compositional matrix adjust.
 Identities = 359/866 (42%), Positives = 556/866 (65%), Gaps = 46/866 (5%)

Query  5    YRPDMIEPKVQQYWAENKVFKAIKDESKEKYYCLSMFPYPSGR-LHMGHVRNYTIGDVIS  63
            Y    IEPK Q +WA+N  FK+  D SK K+Y L MFPYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPFGWDAFGLPAEGAAIKNKTAPAKWTYENIAYMKKQLQLLGFGFDWDR  123
            R++R  G NVL+P GWDAFGLPAE  A+     PA  T ENIA  K+Q++ LGF++DWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EIATCKPDYYKWEQWFFTELYKKGLVYKKTSTVNWCPNDETVLANEQV-HEGCCWRCDTP  182
            E+ T  P+YYKW QW+FT LY KGL Y     VNW  +  T +ANE+V  +G   R + P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VEQKEIPQWFIKITDYAEQLLGGLDTLPQWPDMVKTMQRNWIGRSEGVEITFDVANTNEK  242
            V +K + QW +KIT YAE+LL +L+ + +WP+ +K MQRNWIG+S G ++TF V +T+  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  VAVYTTRPDTFYGVSY--LGIaaahplaslaaQNNSELAAFIQEAK-NAKVAEADLATME  299
             +V+TTRPDT++G +Y  L+   A   A  ++++   +A + ++A  ++ +A +DLA  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGMATGLFAIHPLTGEKLPIWVANFVLMHYGTGAVMAVPAHDQRDFEFAQKYGLQIKQV  359
            K G+ TG +AI+P+ G  +P+W+A++VL  YGTGA+MAVPAHD+RD EFA+++ L+I  V
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  360  IEPIADEEIDLTKQAFTEHGKLVNSAEFDGKDFDGAFNGIADKLEKLGVGKRQVNYRLRD  419
            +E    EE      AFTE+G  +NS  +DG D  +A+  + + LE  GVG+ +V YRLRD
Sbjct  362  LEGGNVEE-----AAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMLTLENGDVVPAPMEDLPIILP--EDVVMDGV-KSPIKADLNWAKT  476
            W  SRQRYWG PIP++  E+G   + P  +LP++LP   D+   G   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  TL-NGAPALKETDTFDTFMESSWYYARYTCPQYQNGMLDAEEANYWLPVDQYIGGIEHAT  535
            T  +G  + +ET+T      SSWYY RY  P+  + + D E  + WLPVD Y+GG EHA 
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLLYFRFFHKLLRDAGFVTSDEPADKLLCQGMVLADAFYYTSPTNERIWVSPTQVTLER  595
            +HLLY RF HK+L D G V + EP +KL+ QGM+L+ ++      + R     + V+ ++
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSR----GALVATDK  587

Query  596  DEKGRIIKATDPEGRELVHSGMTKMSKSKNNGIDPQEMVEKYGADTVRLFMMFASPAEMT  655
             EK R     + E  E ++ + +KMSKS +N ++P+++VE+YGADT+R++ MF +P + +
Sbjct  588  VEK-RDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  656  LEWQESGVEGAKRFLGRVWNLVYQYQQNPAKTSLDLTALSAEQKVLRREVHKTIAKVSDD  715
            + W E G+EG+++FL+RV  L+         T+ ++T    +   L +  + T+  V+++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLI---------TTKEITE--ENSGALDKVYNETVKAVTEQ  695

Query  716  IGRRQTFNTAIAAVMELMNKLTKASLDSEQDRAVMAEALSAVVRMLYPITPHICFELWQA  775
            +++ + FNTAIA +M ++N        ++++  + ++   + V+++ P++PH+  ELWQA
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  776  L-GNESAIDTAEWVKADEAAMVEDEKLIVVQVNGKVRGKVTVAADADEDTVKTIAFADEN  834
            L ++  +I    W   DE+ +VE++  IVVQ++GKV++K+ VA D   + ++ +A+A+E+
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  835  VKKFIDNQHIVKVIYVVGKLLNVVVK  860
            V+  I  ++I+KVI V  KL+N+V+K
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVIK  833

1319) leuS in NC_000907


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  533 bits (2010),  Expect = 3e-152, Method: Compositional matrix adjust.
 Identities = 355/866 (41%), Positives = 560/866 (65%), Gaps = 46/866 (5%)

Query  5    YRPDMIEPKVQQYWAENKVFKAIKDESKEKYYCLSMFPYPSGR-LHMGHVRNYTIGDVIS  63
            Y    IEPK Q +WA+N  FK+  D SK K+Y L MFPYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPFGWDAFGLPAEGAAIKNKTAPAKWTYENIAYMKKQLQLLGFGFDWDR  123
            R++R  G NVL+P GWDAFGLPAE  A+     PA  T ENIA  K+Q++ LGF++DWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EIATCKPEYYKWEQWFFTELYKKGLVYKKTSTVNWCPNDETVLANEQV-HEGCCWRCDTP  182
            E+ T  P+YYKW QW+FT LY KGL Y     VNW  +  T +ANE+V  +G   R + P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VEQKEIPQWFIKITDYAEQLLGGLDTLPQWPDMVKTMQRNWIGRSEGVEITFDVANTNEK  242
            V +K + QW +KIT YAE+LL +L+ + +WP+ +K MQRNWIG+S G ++TF V +T+  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  VAVYTTRPDTFYGVSY--LGIaaahplaslaaQNNSELAAFIQEAK-NAKVAEADLATME  299
             +V+TTRPDT++G +Y  L+   A   A  ++++   +A + ++A  ++ +A +DLA  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGMATGLFAIHPLTGDKLPIWVANFVLMHYGTGAVMAVPAHDQRDFEFAQKYSLPIKQV  359
            K G+ TG +AI+P+ G  +P+W+A++VL  YGTGA+MAVPAHD+RD EFA++++L   ++
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNL---DI  358

Query  360  IAPLADEEIDLTKQAFVEHGKLVNSDEFDGKNFDGAFNGIADKLEKLGVGKRQVNYRLRD  419
            I+ L + +++    AF E+G  +NSD +DG +  +A+  + + LE  GVG+ +V YRLRD
Sbjct  359  IPVLEGGNVE--EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMLTLENGDVVPAPMEDLPIILP--EDVVMDGV-KSPINADPNWAKT  476
            W  SRQRYWG PIP++  E+G   + P  +LP++LP   D+   G   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  TFNDA-PALKETDTFDTFMESSWYYARYTCPQYQNGMLDAEEANYWLPVDQYIGGIEHAT  535
            T +D+  + +ET+T      SSWYY RY  P+  + + D E  + WLPVD Y+GG EHA 
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLLYFRFFHKLLRDAGFVTSEEPADKLLCQGMVLADAFYYTSPTNERIWVSPTQVTLER  595
            +HLLY RF HK+L D G V + EP +KL+ QGM+L+ ++      + R     + V+ ++
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSR----GALVATDK  587

Query  596  DEKGRIIKATDPEGRELVHSGMTKMSKSKNNGIDPQEMVEKYGADTVRLFMMFASPAEMT  655
             EK R     + E  E ++ + +KMSKS +N ++P+++VE+YGADT+R++ MF +P + +
Sbjct  588  VEK-RDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  656  LEWQESGVEGAKRFLGRVWNLVYQYQQNPAKTSLDLTALSAEQKVLRREVHKTIAKVSDD  715
            + W E G+EG+++FL+RV  L+         T+ ++T    +   L +  + T+  V+++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLI---------TTKEITE--ENSGALDKVYNETVKAVTEQ  695

Query  716  IGRRQTFNTAIAAVMELMNKLTKASLDSEQDRAVMAEALSAVVRMLYPITPHICFELWQA  775
            +++ + FNTAIA +M ++N        ++++  + ++   + V+++ P++PH+  ELWQA
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  776  L-GNESAIDTAEWVKADEAAMVEDEKLIVVQVNGKVRGKVTVATDADEDTVKTIAFADEN  834
            L ++  +I    W   DE+ +VE++  IVVQ++GKV++K+ VA D   + ++ +A+A+E+
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  835  VKKFIDNQHIVKVIYVVGKLLNVVVK  860
            V+  I  ++I+KVI V  KL+N+V+K
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVIK  833

1320) leuS in NC_010168


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  533 bits (2010),  Expect = 3e-152, Method: Compositional matrix adjust.
 Identities = 349/856 (41%), Positives = 533/856 (63%), Gaps = 65/856 (7%)

Query  78   YDIAAIEAKWLPRWEEANIFAPLDDGSKERRYVCDMFPYPSG-DLHMGHAEAFVMGDVVG  136
            YD +AIE+KW + W + + F    D+SK + Y  DMFPYPSG +LH+GH+E++   D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  137  RYWKLKGFDVLHPVGWDSFGLPAENAAIKRNAHPAEWTYANIETQAASFKRYAIGVDWSR  196
            R+ + +G +VLHP+GWD+FGLPAE+ A+    +PAE T  NI      ++  +++ DW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  197  RLQTSDPEYYRWTQWLFLRFYERGLAYRKNSPVNWCPKDLTVLANEQVI-NGACERCGTP  255
             ++T+DP+YY+WTQW+F ++YE+GLAY  + PVNW     T +ANE+V+ +G+ ER G P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  256  VTKKNLNQWYFKITDYADRLLDDMAQLEGHWPERVLAMQRNWIGRSQGAHVDFVIDGMSD  315
            V +K + QW +KIT YA+RLL+D+ +++  WPE +  MQRNWIG+S GA+V F +     
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD--WPESIKDMQRNWIGKSTGANVTFKV-----  236

Query  316  AETGEAKKVTVFTTRPDTLYGatffavavdaaladelvtEEQRAELSAYQERVKHLSDIE  375
               +  K  TVFTTRPDTL+GAT+  +A + AL D + T +Q   ++ Y+ +    SD+ 
Sbjct  237  --KDTDKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLA  294

Query  376  RQESDREKTGVFLGRYAINPIDGEMLPIWAADYVLADYGTGAIMAVPAHDQRDLDFARAF  435
            R +  +EKTGV  G YAINP++G  +P+W ADYVLA YGTGAIMAVPAHD+RD +FA+ F
Sbjct  295  RTDLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQF  354

Query  436  DLPVRQVLDTGAENPAETGTAAIGDGVLVNSGELDGLAKAEAIPAAISLLSKIGTGEATT  495
            +L +  VL+ G  +     +A   DG+ +NS+ LDGL KA AI+  +  L   G G+   
Sbjct  355  NLDIIPVLEGGNVE----EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENV  410

Query  496  NYRLRDWLLSRQRFWGAPVPIIHCAECGEVPVPDDQLPVRLPENLRGEQLAPKGTSPLAS  555
             YRLRDWL+SRQR+WG P+PIIH  +    +VP+ +LP+ LP   ++ + +  G SPLA+
Sbjct  411  TYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVT-KDIRPSGTGESPLAN  469

Query  556  VADWVNVDCPKCGGAATRDTDTIDTFVDSSWYYLRYTSPEYTDGPFDPAAATRWMGVDQY  615
            V+DW++V     G  + R+T+T+    +SSWYYLRY  P+ T+   D     +W+ VD Y
Sbjct  470  VTDWLEV-TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIY  528

Query  616  VGGVEHAILHLLYSRFFVKVLNDLGLLEAKEPFKALLNQGQVLNGG--------------  661
            VGG EHA+LHLLY+RF  KVL DLG++ +KEPF+ L+NQG +L  +              
Sbjct  529  VGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKV  588

Query  662  --------------------KAMSKSLGNGVDLSQQLDRFGVDAVRLTMVFASPPEDDVD  701
                                  MSKSL N V+  + ++++G D++R+  +F +P +  + 
Sbjct  589  EKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIA  648

Query  702  WADVSPSGSAKFLARAWRLAQDVTSEIGVDPATGDRALRSVTHRTLSEAADLIDAHKFNV  761
            W++ +  GS KFL R  RL    T EI  + +    AL  V + T+   ++ +D  KFN 
Sbjct  649  WSEEGLEGSRKFLDRVYRLI--TTKEITEENSG---ALDKVYNETVKAVTEQVDQMKFNT  703

Query  762  VVAKTMELVNITRKSIDSGCGPADPavreaveavavILSLFAPYTAEDIWAEL-GHQDFV  820
             +A+ M +VN + K         D    +   +   +++ FAP  +E++W  L +  + +
Sbjct  704  AIAQLMVFVNAANK--------EDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESI  755

Query  821  ARASWPTVDDSLLVQSTITAVVQVQGKVRDRLEVPTDITEDQLRELALASEIVQKTLDGR  880
            +  +WP+ D+S LV++ +  VVQ++GKV+ +L V+ D++ ++L+E+ALA+E VQ  + G+
Sbjct  756  SYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGK  815

Query  881  GIRTVIVRAPKLVNIV  896
            +I  VI  + KLVNIV
Sbjct  816  DIIKVIAVPNKLVNIV  831

1321) ANH9381_0925 in NC_016513


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  532 bits (2009),  Expect = 3e-152, Method: Compositional matrix adjust.
 Identities = 360/866 (42%), Positives = 553/866 (64%), Gaps = 46/866 (5%)

Query  5    YRPDLLEPEVQKFWQDNKTFKAVQDNNKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVVS  63
            Y    +EP  Q FW DN TFK+  D +K K+Y L M+PYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMIGKNVLQPMGWDAFGLPAEGAAVKNNTAPAKWTYENIAYMKNQLQLLGFSYDWDR  123
            R++R  G NVL+PMGWDAFGLPAE  A+     PA  T ENIA  K Q++ LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVTTCRPEYYKWEQWFFTELYKKGLVYKKTSTVNWCPNDKTVLANEQV-HEGCCWRCDTP  182
            EV T  P+YYKW QW+FT LY KGL Y     VNW  +  T +ANE+V  +G   R + P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VEQKEIPQWFIKITDYAEQLLNCLDELPQWPETVKTMQRNWIGRSEGVEITFDIKDTNEK  242
            V +K + QW +KIT YAE+LL+ L+E+ +WPE++K MQRNWIG+S G ++TF +KDT+  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LAVYTTRPDTFYGVSYv--avaaahplatlaaQNNPALAQFIQEAK-NTKVAEADIATME  299
            ++V+TTRPDT++G +Y   A   A   A  ++++  A+A++ ++A  ++ +A +D+A  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGMATGLYAVHPLTGELLPVWVANFVLMHYGTGAVMAVPAHDQRDYEFAQKYGLPIKQV  359
            K G+ TG YA++P+ G  +PVW+A++VL  YGTGA+MAVPAHD+RD EFA+++ L I  V
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  360  IEPIHGEEIDLTKQAFTEHGKLIYSAEFDGLEFDAAFSGIADKLEQLGMGKRQVNYRLRD  419
            +E  + EE      AFTE+G  I S  +DGL+  +A++ + + LE  G+G+ +V YRLRD
Sbjct  362  LEGGNVEE-----AAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGALIPMLTLENGDVVPAPMEDLPIILP--EDVVMNGV-NSPIKADPEWAKT  476
            W  SRQRYWG  IP++  E+G   + P  +LP++LP   D+  +G  +SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  TYQ-GKPALRETDTFDTFMESSWYYARYTCPEYQQGMLNSEEANYWLPVDQYIGGIEHAT  535
            T + G  + RET+T      SSWYY RY  P+  + + + E  + WLPVD Y+GG EHA 
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLLYFRFFHKLLRDAGFVTSDEPANKLLCQGMVLADAFYYTSPTNERIWVSPTKVTLER  595
            +HLLY RF HK+L D G V + EP +KL+ QGM+L+ ++      + R     + V+ ++
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSR----GALVATDK  587

Query  596  DDKGRIVKATDDEGHELVHAGMTKMSKSKNNGIDPQEMVEKYGADTVRLFMMFASPAEMT  655
             +K        + G+EL +A  +KMSKS +N ++P+++VE+YGADT+R++ MF +P + +
Sbjct  588  VEKRDGSFFHVETGEELEQAP-AKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  656  LEWQESGVEGAKRFLARVWNLVFEYNKNPAKTPLNPTALSAAQKALRRDVHKTIAKVSDD  715
            + W E G+EG+++FL RV  L+                      AL +  + T+  V+++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLI-----------TTKEITEENSGALDKVYNETVKAVTEQ  695

Query  716  IGRRQTFNTAIAAIMELMNKLTRAPLDDEQDRAMMAEALSAVVRMLYPITPHICFRLWQE  775
            +++ + FNTAIA +M ++N         +++  + ++   + V+++ P++PH+   LWQ 
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  776  L-GNQDIIDFAPWVEADAEAMIEDEKLIVVQVNGKVRGKVTVAADADEDTVKAVAFADEN  834
            L ++ + I + PW   D   ++E++  IVVQ++GKV++K+ VA D   + ++ VA+A+E+
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  835  VKRFTDGMQIVKVIYVAGKLLNVVVK  860
            V+    G +I+KVI V+ KL+N+V+K
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVIK  833

1322) leuS in NC_014562


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  532 bits (2009),  Expect = 3e-152, Method: Compositional matrix adjust.
 Identities = 358/876 (41%), Positives = 550/876 (63%), Gaps = 68/876 (7%)

Query  5    YRPEEIESRVQQHWDENETFKVTEQEGKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIA  63
            Y    IE++ Q  W +N+TFK   + +K K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKLLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCQPEYYRWEQWFFTKLYEKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T +P+YY+W QW+FTKLYEKGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITDYAeellndldtleeWPEQVKTMQRNWIGRSEGVEITFDVADSEEK  242
            V RK + QW +KIT YA E L +     +WPE +K MQRNWIG+S G ++TF V D++  
Sbjct  184  VVRKPMRQWMLKITAYA-ERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  VTVYTTRPDTFIGATYVAVAAGHPLATQASVNNPALADFIAECRNTKVAEADMA----TM  298
             TV+TTRPDT++GATY  +A+ H+L    ++  +  A+ +A+ +      +D+A    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALV--DAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  299  EKKGMATGLSVIHPLTGELLPVWVANFVLMEYGTGAVMAVPAHDQRDWEFATKYDLAIKP  358
            EK G+ TG   I+P+ G  +PVW+A++VL  YGTGA+MAVPAHD+RDWEFA +++L I P
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VVLNLDGSIPDVSAAAMTDKGALFNSGEFNGLDHAAGFTAIADSLAAKGVGVRKVNYRLR  418
            V   L+G+  +V  AA T+ G  +NS+ ++GLD A++++ + + L A GVG  +V YRLR
Sbjct  361  V---LEGG--NVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  419  DWGVSRQRYWGAPIPMVTLEDGTVMPTPEDQLPVILP--EDVVMNGIT-SPIKADPDWAK  475
            DW  SRQRYWG PIP++  EDGT  + PE +LP++LP   D+  +G   SP+    DW  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  476  TT-VNGQPALRETDTFDTFMESSWYYARYTCASYKEGMLDPAAANYWLPVDQYVGGIEHA  534
             T  +G  + RET+T      SSWYY RY  +   E + D    + WLPVD YVGG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  535  IMHLMYFRFFHKLLRDAGLVNSDEPAKRLLCQGMVLADAFYYLGNNGERNWVSPVDVEVE  594
            ++HL+Y RF HK+L D G+V + EP ++L+ QGM+L+ ++                    
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY--------------------  575

Query  595  RDEKGRIVKAVDTQGREVIY----------AGMSKMSKSKNNGIDPQLMVERYGADTVRL  644
            RD +G +V +   + R+  +           + +KMSKS +N ++P+ +VE+YGADT+R+
Sbjct  576  RDSRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRV  635

Query  645  FMMFASPADMTLEWQESGVEGANRFLKRVWKLVYEHTSQGATVALDVQSLNDEQKSLRRD  704
            + MF +P D ++ W E G+EG+ +FL RV +L+   T++  T        +++  +L + 
Sbjct  636  YEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLI---TTKEIT--------EENSGALDKV  684

Query  705  LHKTIAKVADDIGRRQTFNTAIAAIMELMNKLARAPQESEQDRALMQEALLAIVRLLYPF  764
             + T+  V++++++ + FNTAIA +M ++N        ++++  L  +   ++V+L+ PF
Sbjct  685  YNETVKAVTEQVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPF  736

Query  765  TPHACYVLWQTLGGEG-TIDEASWPVADEAAMVEDSLLVVVQVNGKVRGKITVPADATQE  823
            +PH    LWQ+L + G +I   +WP  DE+ +VE+ + +VVQ++GKV++K+ V+ D ++E
Sbjct  737  APHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSRE  796

Query  824  QVQARAAQEHLVAKYLDGVTIRKVIYVPGKLLNLVV  859
            ++Q  A  ++ V   + G  I KVI VP KL+N+V+
Sbjct  797  ELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

1323) leuS in NC_007164


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  532 bits (2008),  Expect = 4e-152, Method: Compositional matrix adjust.
 Identities = 359/767 (47%), Positives = 509/767 (67%), Gaps = 89/767 (11%)

Query  218  LVYRSNSTVNWCPGLGTVLANEEVTAEGRSERGNFPVFRKNLQQWMMRITAYSDRLIDDL  277
            L Y ++  VNW   LGT +ANEEV ++G SERG +PV RK ++QWM++ITAY++RL++DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  278  EYLDWPEKVKSMQRNWIGRSRGAEVTFDC--LGNDIDVFTTRPDTLFGATYMVLAPEHEL  335
            E +DWPE +K MQRNWIG+S GA+VTF     ++D+ VFTTRPDTLFGATY VLAPEH L
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  336  VDTLVAQSGNSSSGSDAYTDVDPRWTYGQanpaaaveayraaiaaKSDLERQE-NKEKTG  394
            VD++   +++ + +   Y    +                      KSDL R +  KEKTG
Sbjct  268  VDAIT--TSDQAEAVADYKRQAS---------------------LKSDLARTDLAKEKTG  304

Query  395  VFLGVYATNPVNGAQVPVFIADYVLTGYGTGAIMAVPAHDSRDFEFATEFGLPIVPVLAP  454
            V  G YA NPVNG ++PV IADYVL++YGTGAIMAVPAHD RD EFA +F L I+PVL  
Sbjct  305  VWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEG  364

Query  455  egaeagageqggaelteaFTEDGPHINSNNSDGLELNGLGKAEAIDKAIEWLESKGVGSG  514
               E +A           FTEDG HINS+      L+GL+KA AI K +EWLE+ GVG+ 
Sbjct  365  GNVEEAA-----------FTEDGLHINSDF-----LDGLDKASAIAKMVEWLEAEGVGNE  408

Query  515  KIQYKLRDWLFARQRYWGEPFPIVYDEDGTAHGLPEDMLPVELPEVEDYKPVSFDPDDKD  574
            ++ Y+LRDWLF+RQRYWGEP+PI+  EDGT+ ++PE  LP+ LP   D +P         
Sbjct  409  NVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------S  460

Query  575  SAPQPPLAKAKDWVEVTLDLGDGEKTYYRDTNVMPQWAGSSWYQLRYIDPNNDNALVDIE  634
            ++ ++PLA+  DW+EVT + G   +   R+TN MPQWAGSSWY LRYIDP+N + L D E
Sbjct  461  GTGESPLANVTDWLEVTREDGVKGR---RETNTMPQWAGSSWYYLRYIDPHNTEKLADEE  517

Query  635  NERYWVGPREGRPSGGVDLYVGGVEHAVLHLLYARFWHKVLFDLGVVSSFEPYYRLYNQG  694
              + W+          VD+YVGG EHAVLHLLYARFWHKVL+DLGVV++ EP+ +L+NQG
Sbjct  518  LLKQWLP---------VDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQG  568

Query  695  YIQAYAYTDSRGVYVPAEEVTERDGKFFWVRKADDAEGVTKEEEVFQEYGKMGKSLKNAV  754
             I + +Y DSRG  V+++ V  RDG FF V  +++ E            +KM+KSLKN V
Sbjct  569  MILGTSYRDSRGALVATDKVEKRDGSFFHVETGEELEQAP---------AKMSKSLKNVV  619

Query  755  SPDEICDDYGADTLRVYEMAMGPLDTSRPWATKDVVGAQRFLQRAWRLAVDENTGKGSVS  814
            +PD++ ++YGADTLRVYEM MGPLD+S +W+  ++ G+++FL+R  RL          ++
Sbjct  620  NPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRL----------IT  669

Query  815  DDALTDEDLKALHR----TIAGVHENYAELRDNTAVAKLIEYVNYLTKTYSAGQAPRAAV  870
               +T+E+  AL++    T+ +V E+  +++ NTA+A+L+ +VN   K    ++      
Sbjct  670  TKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANK---EDKLFSDYA  726

Query  871  EPLVQMLSPVAPHIAEEMWEIL-GHSEGITYESFPEWDEKWLVDDTIELPVQVMGKLRGR  929
              +VQ+++P APH++EE+W+ L + +E+I+Y + P  DE  LV++ +E+ VQ+ GK++++
Sbjct  727  KGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAK  786

Query  930  INVAADASREDIEAAALEEPNVASHIEGKTVAKIIVVPGKMVNIVAK  976
            + VA D SRE+++  AL + +V ++I GK + K+I VP K+VNIV K
Sbjct  787  LVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833


 Score =  131 bits (482),  Expect = 2e-31, Method: Compositional matrix adjust.
 Identities = 76/150 (51%), Positives = 103/150 (69%), Gaps = 10/150 (6%)

Query  19   AKIEAKWQKHWADKGTFNAPNPTGDLAEPGAELPEDRKFIQDMFPYPSGVGLHVGHPLGY  78
            + IE+KWQ  WAD+ TF++          G++ +  + +  DMFPYPSG GLHVGHP GY
Sbjct  7    TAIEPKWQAFWADNHTFKT----------GTDASKPKFYALDMFPYPSGAGLHVGHPEGY  56

Query  79   IGTDVFARFHRMKGANVLHTLGYDAFGLPAEQYAVQTGTHPRTTTMANIANMERQLGRLG  138
             +TD+++RF R +G NVLH +G DAFGLPAEQYA++TG +P   T  NIAN  RQ+  LG
Sbjct  57   TATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALG  116

Query  139  LGHDKRRSFATTDTDYYRWTQWIFLQIYNS  168
            ++ D  R   TTD +YY+WTQWIF ++Y+ 
Sbjct  117  FSYDWDREVNTTDPNYYKWTQWIFTKLYEK  146

1324) leuS in NC_017910


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  532 bits (2008),  Expect = 4e-152, Method: Compositional matrix adjust.
 Identities = 357/865 (42%), Positives = 552/865 (64%), Gaps = 46/865 (5%)

Query  5    YRPEEIESHVQQQWEEKRTFEVKEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVVA  63
            Y    IE+  Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYANIEYMKNQLKMLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T  NI   K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EIATCKPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDKTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITDYAEELLNDLDKLDHWPDQVKTMQRNWIGRSEGVEITFDVKDSDQK  242
            V RK + QW +KIT YAE LL+DL+ +D WP+ +K MQRNWIG+S G ++TF VKD+D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGATY--LavaaghplaqqaaagNPQLAAFV-EECRNTKVAEADMATME  299
            +TV+TTRPDT+ GATY  LA   +   A  ++     +A +  +   ++ +A +D+A  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGIATGYYAIHPLTGEAIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFATKYHLPVKAV  359
            K G+ TG YAI+P+ G  +PVW A++VL  YGTGA+MAVP+HD+RD EFA +++L + +V
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  360  ILAADGTAPDLSSQAMTEKGVLFNSGEFDGLDFTAGFNAIADKLASMGVGERKVNYRLRD  419
            +      + ++   A TE G+ +NS+ +DGLD ++++  + + L + GVG+ +V YRLRD
Sbjct  362  L-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMVTLEDGTVIPTPDDQLPVILP--EDVVMDGIT-SPIKADPEWAKT  476
            W  SRQRYWG PIP++  EDGT  + P+ +LP++LP   D+   G   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  T-VNGMPALRETDTFDTFMESSWYYARYTCPQYDKGMLDSDAANYWLPVDIYIGGIEHAI  535
            T  +G+ + RET+T      SSWYY RY  P+    + D +  + WLPVDIY+GG EHA+
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYTGVNGERNWVSPVDAITDR  595
            +HLLY RF HK++ D G+V + EP ++L+ QGM+L+ +  Y +  G    + + D +  R
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS--YRDSRGA---LVATDKVEKR  591

Query  596  DEKGRITAARDAAGHELVYAGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMT  655
            D     +  +  +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D +
Sbjct  592  DG----SFFHVETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  656  LEWQESGVEGANRFLKRVWKLVYEHTakgaaaaldvaaLSEDQKALRRDVHKTIAKVTDD  715
            + W E G+EG+ +FL RV +L+                  E+  AL +  + T+  VT++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLI-----------TTKEITEENSGALDKVYNETVKAVTEQ  695

Query  716  IGRRQTFNTAIAAIMELMNKLARAPQDSEQDRALMNEALLAVVRMLYPFTPHVCFTMWQA  775
            +++ + FNTAIA +M ++N        ++++  L ++   + V+++ PF+PH+   +WQA
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  776  LAGNGD-IDNAPWPQADDSAMVEDSVLVVVQVNGKVRGKITVAADATEEQVRELAGQEHL  834
            L+++G+ I   PWP  D+S +VE+ V +VVQ++GKV++K+ VA D + E+++E+A  ++ 
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  835  VAKHLEGKTIRKVIYVAGKLLNLVV  859
            V  ++ GK I KVI V+ KL+N+V+
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVI  832

1325) leuS in NC_011274


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  532 bits (2007),  Expect = 4e-152, Method: Compositional matrix adjust.
 Identities = 363/866 (42%), Positives = 551/866 (64%), Gaps = 48/866 (5%)

Query  5    YRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVVA  63
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKTLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q+++LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EIATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADELLRDLDKLDHWPDTVKTMQRNWIGRSEGVEITFDVKGYDNT  242
            V RK + QW +KITAYA+ LL DL+ +D WP+++K MQRNWIG+S G ++TF VK+ D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGATYLAVAAGHPlaqkaaannaelaaFIDECRNTKVAEAEMA----TM  298
            +TV+TTRPDT+ GATY  +A+ H+L +  ++++   A  + + +      +++A    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEA--VADYKRQASLKSDLARTDLAK  300

Query  299  EKKGVDTGFKATHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLTIKP  358
            EK GV TG  A +P+ G E+PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L I P
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VILAADGSEPDLSEQALTEKGVLFNSGEFDGLAFEAAFNAIADKLAEKGVGERKVNYRLR  418
            V+        ++ E A+TE G+ +NS+ +DGL   +A+  + + L   GVG+ +V YRLR
Sbjct  361  VL-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  419  DWGVSRQRYWGAPIPMVTLEDGTVLPTPEDQLPVILP--EDVVMDGIT-SPIKADPEWAK  475
            DW  SRQRYWG PIP++  EDGT  + PE +LP++LP   D+   G   SP+    +W  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  476  TT-VNGMPALRETDTFDTFMESSWYYARYTCPQYQEGMLDSKAANYWLPVDIYIGGIEHA  534
             T  +G+ + RET+T      SSWYY RY  P+  E + D    + WLPVDIY+GG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  535  IMHLLYFRFFHKLMRDAGMVTSDEPAKKLLCQGMVLADAFYYVGENGERNWVSPVDAIVE  594
            ++HLLY RF HK++ D G+V + EP +KL+ QGM+L+ ++      + R  + + D +  
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEK  590

Query  595  RDEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADM  654
            RD  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D 
Sbjct  591  RD--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  655  TLEWQESGVEGANRFIKRVWKLVYEHTAKGPVAALNVDALSEDQKALRRDVHKTIAKVTD  714
            ++ W E G+EG+ +F+ RV +L+   T+K        +   E+  AL +  + T+  VT+
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLI---TTK--------EITEENSGALDKVYNETVKAVTE  694

Query  715  DVGRRQTFNTAIAAIMELMNKLAKAPQEGEQDRALLQEALQAVVRMLNPFTPHVCFTLWQ  774
            +V++ + FNTAIA +M ++N        ++++  L+ +  ++ V+++ PF+PH+   LWQ
Sbjct  695  QVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  775  ELGGEGD-IDNAPWPVADEQAMVENTTLVVVQVNGKVRGKITVAVDATEEQVRERAGQEH  833
             L + G+ I   PWP  DE  +VEN   +VVQ++GKV++K+ VA D + E+++E A  ++
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  834  LVAKYLDGVTVCKVIYVPGKLLNLVV  859
             V   + G  + KVI VP KL+N+V+
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVI  832

1326) HIB_10530 in NC_016809


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  532 bits (2008),  Expect = 4e-152, Method: Compositional matrix adjust.
 Identities = 355/866 (41%), Positives = 557/866 (65%), Gaps = 46/866 (5%)

Query  5    YRPDMIEPKVQQYWAENKVFKAIKDESKEKYYCLSMFPYPSGR-LHMGHVRNYTIGDVIS  63
            Y    IEPK Q +WA+N  FK+  D SK K+Y L MFPYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPFGWDAFGLPAEGAAIKNKTAPAKWTYENIAYMKKQLQLLGFGFDWDR  123
            R++R  G NVL+P GWDAFGLPAE  A+     PA  T ENIA  K+Q++ LGF++DWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EIATCKPEYYKWEQWFFTELYKKGLVYKKTSTVNWCPNDETVLANEQV-HEGCCWRCDTP  182
            E+ T  P+YYKW QW+FT LY KGL Y     VNW  +  T +ANE+V  +G   R + P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VEQKEIPQWFIKITDYAEQLLGGLDALPQWPDMVKTMQRNWIGRSEGVEITFDVANTNEK  242
            V +K + QW +KIT YAE+LL +L+ + +WP+ +K MQRNWIG+S G ++TF V +T+  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  VAVYTTRPDTFYGVSY--LGIaaahplaslaaQNNPELAAFIQEAK-NAKVAEADLATME  299
             +V+TTRPDT++G +Y  L+   A   A  ++++   +A + ++A  ++ +A +DLA  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGMATGLFAIHPLTGEKLPIWVANFVLMHYGTGAVMAVPAHDQRDFEFAQKYSLPIKQV  359
            K G+ TG +AI+P+ G  +P+W+A++VL  YGTGA+MAVPAHD+RD EFA++++L   ++
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNL---DI  358

Query  360  IAPLANEEIDLTKQAFVEHGKLVNSAEFDGKDFDGAFNGIADKLEKLGVGKRQVNYRLRD  419
            I+ L   +++    AF E+G  +NS  +DG D  +A+  + + LE  GVG+ +V YRLRD
Sbjct  359  IPVLEGGNVE--EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMLTLENGDVVPAPLEDLPIILP--EDVVMDGV-KSPIKADPNWAKT  476
            W  SRQRYWG PIP++  E+G   + P  +LP++LP   D+   G   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  TL-NGTPASKETDTFDTFMESSWYYARYTCPQYQNGMLDAEEANYWLPVDQYIGGIEHAT  535
            T  +G  + +ET+T      SSWYY RY  P+  + + D E  + WLPVD Y+GG EHA 
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLLYFRFFHKLLRDAGFVTSDEPADKLLCQGMVLADAFYYTSPTNERIWVSPTQVTLER  595
            +HLLY RF HK+L D G V + EP +KL+ QGM+L+ ++      + R     + V+ ++
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSR----GALVATDK  587

Query  596  DEKGRIIKATDPEGRELVHSGMTKMSKSKNNGIDPQEMVEKYGADTVRLFMMFASPAEMT  655
             EK R     + E  E ++ + +KMSKS +N ++P+++VE+YGADT+R++ MF +P + +
Sbjct  588  VEK-RDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  656  LEWQESGVEGAKRFLGRVWNLVYQYQQNPAKTSLDLTALSAEQKVLRREVHKTIAKVSDD  715
            + W E G+EG+++FL+RV  L+         T+ ++T    +   L +  + T+  V+++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLI---------TTKEITE--ENSGALDKVYNETVKAVTEQ  695

Query  716  IGRRQTFNTAIAAVMELMNKLTKASLDSEQDRAVMAEALSAVVRMLYPITPHICFELWQA  775
            +++ + FNTAIA +M ++N        ++++  + ++   + V+++ P++PH+  ELWQA
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  776  L-GNESAIDTAEWVKADEAAMVEDEKLIVVQVNGKVRGKVTVAADADEDTVKTIAFADEN  834
            L ++  +I    W   DE+ +VE++  IVVQ++GKV++K+ VA D   + ++ +A+A+E+
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  835  VKKFIDNQHIVKVIYVVGKLLNVVVK  860
            V+  I  ++I+KVI V  KL+N+V+K
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVIK  833

1327) NT08PM_2253 in NC_017764


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  532 bits (2007),  Expect = 4e-152, Method: Compositional matrix adjust.
 Identities = 353/866 (41%), Positives = 563/866 (66%), Gaps = 46/866 (5%)

Query  5    YRPDLIEAEVQQYWAENKTFKAIKDTNKPKYYCLSMFPYPSGR-LHMGHVRNYTIGDVVS  63
            Y    IE+  Q +WA+N TFK+  D++KPK+Y L MFPYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMNGKNVLQPMGWDAFGLPAEGAAIKNKTAPAKWTYENIDYMKNQLKILGFGFDWDR  123
            R++R +G NVL+PMGWDAFGLPAE  A+     PA  T ENI   K Q++ LGF++DWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVTTCKPDYYKWEQWFFTELYKKGLVYKKTSTVNWCPNDETVLANEQV-HEGCCWRCDTP  182
            EV T  P+YYKW QW+FT LY KGL Y     VNW  +  T +ANE+V  +G   R + P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VEQKEIPQWFIKITDYAEQLLGGLDHLPLWPDQVKTMQRNWIGRSEGVEITFQLANSEDN  242
            V +K + QW +KIT YAE+LL +L+++  WP+ +K MQRNWIG+S G ++TF++ +++ +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFFGVSY--VavaaahplaekaaENNPELAQFIQECK-NTKVAEAELATME  299
            +TV+TTRPDT+FG +Y  +A   A   A  ++++   +A++ ++   ++ +A ++LA  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGMATGVYAIHPLTGEKVPVWVANFVLMHYGTGAVMAVPGHDERDAEFARKYGLPLLNV  359
            K G+ TG YAI+P+ G  +PVW+A++VL  YGTGA+MAVP+HDERD EFA+++ L ++ V
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  360  IKPINGEPLPEHELPYCEHGILFNSGEFNGLDFDAAFNTIADKLEALGKGKRQVNYRLRD  419
            +   N E     E ++ E+G+ +NS+ ++GLD  +A+  + + LEA G G+ +V YRLRD
Sbjct  362  LEGGNVE-----EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMLTLENGEVVPAPLQDLPIELP--EDVVMDGV-KSPIKADPEWAKT  476
            W  SRQRYWG PIP++  E+G   + P  +LP+ LP   D+   G   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  TY-NGQPALKETDTFDTFMESSWYYARYTSPKFAEAMLDADEANYWLPVDQYIGGIEHAT  535
            T  +G  + +ET+T      SSWYY RY  P  +E + D +  + WLPVD Y+GG EHA 
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLLYFRFFHKLLRDAGFVTSDEPADKLLCQGMVLADAFYYTSPTNERIWVSPTEVTLER  595
            +HLLY RF HK+L D G V + EP +KL+ QGM+L+ ++      + R     + V+ ++
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSR----GALVATDK  587

Query  596  DEKGRILKAFDKEGRELVHSGMTKMSKSKNNGIDPQEMVEKYGADTVRLFMMFASPAEMT  655
             EK R    F+ E  E ++ + +KMSKS +N ++P+++VE+YGADT+R++ MF +P + +
Sbjct  588  VEK-RDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  656  LEWQESGVEGAKRFLGRLWNLVFEYNKHPAETAVEPTALSSAQKALRRDVHKTIAKVSDD  715
            + W E G+EG+++FL+R+  L+        E + E ++      AL +  + T+  V+++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLI-----TTKEITEENSG------ALDKVYNETVKAVTEQ  695

Query  716  IGRRQTFNTAIAAIMELMNKLTKAPLVEVQDRAIMAEALSAVVRMLYPITPHICFQLWKD  775
            +++ + FNTAIA +M ++N   K       +  + ++   + V+++ P++PH+  +LW+ 
Sbjct  696  VDQMK-FNTAIAQLMVFVNAANK-------EDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  776  L-GNTEAIDFAPWveadaaamvddeKLVVVQVNGKVRAKVTVPAEMSEDDIKQVALADGN  834
            L ++ E+I + PW   D + +V+++  +VVQ++GKV+AK+ V+ ++S +++++VALA+ +
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  835  VAKHLEGLNIVKTIYVPGKLFSFVAK  860
            V  ++ G +I+K I VP KL ++V K
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVIK  833

1328) leuS in NC_016808


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  532 bits (2008),  Expect = 4e-152, Method: Compositional matrix adjust.
 Identities = 353/866 (41%), Positives = 564/866 (66%), Gaps = 46/866 (5%)

Query  5    YRPDLIEAEVQQYWAENKTFKAIKDTNKPKYYCLSMFPYPSGR-LHMGHVRNYTIGDVVS  63
            Y    IE+  Q +WA+N TFK+  D++KPK+Y L MFPYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMNGKNVLQPMGWDAFGLPAEGAAIKNKTAPAKWTYENIDYMKNQLKILGFGFDWDR  123
            R++R +G NVL+PMGWDAFGLPAE  A+     PA  T ENI   K Q++ LGF++DWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVTTCKPDYYKWEQWFFTELYKKGLVYKKTSTVNWCPNDETVLANEQV-HEGCCWRCDTP  182
            EV T  P+YYKW QW+FT LY KGL Y     VNW  +  T +ANE+V  +G   R + P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VEQKEIPQWFIKITDYAEQLLGGLDHLPLWPDQVKTMQRNWIGRSEGVEITFQLANSEDN  242
            V +K + QW +KIT YAE+LL +L+++  WP+ +K MQRNWIG+S G ++TF++ +++ +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFFGVSY--VavaaahplaekaaENNPELAQFIQECK-NTKVAEAELATME  299
            +TV+TTRPDT+FG +Y  +A   A   A  ++++   +A++ ++   ++ +A ++LA  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGMATGVYAIHPLTGGKVPVWVANFVLMNYGTGAVMAVPGHDERDAEFARKYGLPLLNV  359
            K G+ TG YAI+P+ G  +PVW+A++VL +YGTGA+MAVP+HDERD EFA+++ L ++ V
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  360  IKPINGEPLPEHELPYCEHGILFNSGEFNGLDFDAAFNAIADKLEALGKGKRQVNYRLRD  419
            +   N E     E ++ E+G+ +NS+ ++GLD  +A+  + + LEA G G+ +V YRLRD
Sbjct  362  LEGGNVE-----EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMLTLENGEVVPAPLQDLPIELP--EDVVMDGV-KSPIKADPEWAKT  476
            W  SRQRYWG PIP++  E+G   + P  +LP+ LP   D+   G   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  TY-NGQPALKETDTFDTFMESSWYYARYTSPKFAETMLDADEANYWLPVDQYIGGIEHAT  535
            T  +G  + +ET+T      SSWYY RY  P  +E + D +  + WLPVD Y+GG EHA 
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLLYFRFFHKLLRDAGFVTSDEPADKLLCQGMVLADAFYYTSPTNERIWVSPTEVTLER  595
            +HLLY RF HK+L D G V + EP +KL+ QGM+L+ ++      + R     + V+ ++
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSR----GALVATDK  587

Query  596  DEKGRILKAFDKEGRELVHSGMTKMSKSKNNGIDPQEMVEKYGADTVRLFMMFASPAEMT  655
             EK R    F+ E  E ++ + +KMSKS +N ++P+++VE+YGADT+R++ MF +P + +
Sbjct  588  VEK-RDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  656  LEWQESGVEGAKRFLGRLWNLVFEYNKHPAETAVEPTALSSAQKALRRDVHKTIAKVSDD  715
            + W E G+EG+++FL+R+  L+        E + E ++      AL +  + T+  V+++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLI-----TTKEITEENSG------ALDKVYNETVKAVTEQ  695

Query  716  IGRRQTFNTAIAAIMELMNKLTKSPLVEVQDRAIMAEALSAVVRMLYPITPHICFQLWKD  775
            +++ + FNTAIA +M ++N   K       +  + ++   + V+++ P++PH+  +LW+ 
Sbjct  696  VDQMK-FNTAIAQLMVFVNAANK-------EDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  776  L-GNTEAIDFAPWveadaaamvddeKLVVVQVNGKVRAKVTVPAEMSEDDIKQVALADSN  834
            L ++ E+I + PW   D + +V+++  +VVQ++GKV+AK+ V+ ++S +++++VALA+ +
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  835  VAKHLEGLNIVKTIYVPGKLFSFVAK  860
            V  ++ G +I+K I VP KL ++V K
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVIK  833

1329) leuS in NC_002663


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  532 bits (2008),  Expect = 4e-152, Method: Compositional matrix adjust.
 Identities = 354/866 (41%), Positives = 563/866 (66%), Gaps = 46/866 (5%)

Query  5    YRPDLIEAEVQQYWAENKTFKAIKDTNKPKYYCLSMFPYPSGR-LHMGHVRNYTIGDVVS  63
            Y    IE+  Q +WA+N TFK+  D++KPK+Y L MFPYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMNGKNVLQPMGWDAFGLPAEGAAIKNKTAPAKWTYENIDYMKNQLKILGFGFDWDR  123
            R++R +G NVL+PMGWDAFGLPAE  A+     PA  T ENI   K Q++ LGF++DWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVTTCKPDYYKWEQWFFTELYKKGLVYKKTSTVNWCPNDETVLANEQV-HEGCCWRCDTP  182
            EV T  P+YYKW QW+FT LY KGL Y     VNW  +  T +ANE+V  +G   R + P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VEQKEIPQWFIKITDYAEQLLGGLDHLPLWPDQVKTMQRNWIGRSEGVEITFQLANSEDN  242
            V +K + QW +KIT YAE+LL +L+++  WP+ +K MQRNWIG+S G ++TF++ +++ +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFFGVSY--VavaaahplaekaaENNPELAQFIQECK-NTKVAEAELATME  299
            +TV+TTRPDT+FG +Y  +A   A   A  ++++   +A++ ++   ++ +A ++LA  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGMATGVYAIHPLTGEKVPVWVANFVLMHYGTGAVMAVPGHDERDAEFARKYGLPLLNV  359
            K G+ TG YAI+P+ G  +PVW+A++VL  YGTGA+MAVP+HDERD EFA+++ L ++ V
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  360  IKPINGEPLLEHELPYCEHGILFNSGEFNGLDFDAAFNAIADKLEALGKGKRQVNYRLRD  419
            +   N E     E ++ E+G+ +NS+ ++GLD  +A+  + + LEA G G+ +V YRLRD
Sbjct  362  LEGGNVE-----EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMLTLENGEVVPAPLQDLPIELP--EDVVMDGV-KSPIKADPEWAKT  476
            W  SRQRYWG PIP++  E+G   + P  +LP+ LP   D+   G   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  TY-NGQPALKETDTFDTFMESSWYYARYTSPKFAEAMLDADEANYWLPVDQYIGGIEHAT  535
            T  +G  + +ET+T      SSWYY RY  P  +E + D +  + WLPVD Y+GG EHA 
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLLYFRFFHKLLRDAGFVTSDEPADKLLCQGMVLADAFYYTSPTNERIWVSPTEVTLER  595
            +HLLY RF HK+L D G V + EP +KL+ QGM+L+ ++      + R     + V+ ++
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSR----GALVATDK  587

Query  596  DEKGRILKAFDKEGRELVHSGMTKMSKSKNNGIDPQEMVEKYGADTVRLFMMFASPAEMT  655
             EK R    F+ E  E ++ + +KMSKS +N ++P+++VE+YGADT+R++ MF +P + +
Sbjct  588  VEK-RDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  656  LEWQESGVEGAKRFLGRLWNLVFEYNKHPAETTVEPTALSSAQKALRRDVHKTIAKVSDD  715
            + W E G+EG+++FL+R+  L+        E T E ++      AL +  + T+  V+++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLI-----TTKEITEENSG------ALDKVYNETVKAVTEQ  695

Query  716  IGRRQTFNTAIAAIMELMNKLTKAPLVEVQDRAIMAEALSAVVRMLYPITPHICFQLWKD  775
            +++ + FNTAIA +M ++N   K       +  + ++   + V+++ P++PH+  +LW+ 
Sbjct  696  VDQMK-FNTAIAQLMVFVNAANK-------EDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  776  L-GNTEAIDFAPWveadaaamvddeKLVVVQVNGKVRAKVTVPAEMSEDDIKQVALADSN  834
            L ++ E+I + PW   D + +V+++  +VVQ++GKV+AK+ V+ ++S +++++VALA+ +
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  835  VAKHLEGLNIVKTIYVPGKLFSFVAK  860
            V  ++ G +I+K I VP KL ++V K
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVIK  833

1330) leuS in NC_013421


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  532 bits (2007),  Expect = 4e-152, Method: Compositional matrix adjust.
 Identities = 353/876 (41%), Positives = 545/876 (63%), Gaps = 68/876 (7%)

Query  5    YRPEEIEADVQLHWQEKQTFKVTEQPGKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIS  63
            Y    IE+  Q  W +++TFK   +++K K+Y L M+PYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYANIDYMKNQLKLLGFGYDWDR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T  NI   K Q++ LGF+YDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVATCKPDYYRWEQWFFTKLYEKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            EV T  P+YY+W QW+FTKLYEKGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADQLLNDLDTLESWPEQVKTMQRNWIGRSEGVEITFDVADSTEK  242
            V RK + QW +KITAYA++LL+DL+ ++ WPE +K MQRNWIG+S G ++TF V D+   
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LSVYTTRPDTFMGVTYVavaaghplaaqaaatnpalaDFIAECRNTKVAEADMA----TM  298
            ++V+TTRPDT+ G TY     +   A   A T +  A+ +A+ +      +D+A    + 
Sbjct  243  FTVFTTRPDTLFGATYA--VLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  299  EKKGIATGLYAIHPLNGEKVAIWVANFVLMEYGTGAVMAVPGHDQRDWEFATKYDLSIKP  358
            EK G+ TG YAI+P+NG  +++W+A++VL  YGTGA+MAVP+HD+RDWEFA +++L I P
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VILNADGSKPDLSTEAMTEKGSLFNSGEFDGLDFDAAFNAIADKLVEKGIGERKVNYRLR  418
            V+  ++   + ++ +++  ++ +     +DGLD  +A+  + + L   G+G+ +V YRLR
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDF-----LDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  419  DWGVSRQRYWGAPIPMVTLEDGTVIPTPEDQLPVILP--EDVVMDGIT-SPLKSNPEWAK  475
            DW  SRQRYWG PIP++  EDGT  + PE +LP++LP   D+   G   SPL +  +W  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  476  TT-VNGQPALRETDTFDTFMESSWYYARYTCPQYDQGMLDPAAANYWLPVDQYVGGIEHA  534
             T  +G  + RET+T      SSWYY RY  P+  + + D    + WLPVD YVGG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  535  IMHLMYFRFFHKLMRDAGLVTSDEPAKRLLCQGMVLADAFYYLGNNGERIWVSPADVTVE  594
            ++HL+Y RF HK++ D G+V + EP ++L+ QGM+L+ ++                    
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY--------------------  575

Query  595  RDEKGRIVKAVDNEGRDVIY----------AGMSKMSKSKNNGIDPQVMVEKYGADTVRL  644
            RD +G +V +   E RD  +           + +KMSKS +N ++P+ +VE+YGADT+R+
Sbjct  576  RDSRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRV  635

Query  645  FMMFASPAEMTLEWQESGVEGANRFLKRVWRQAFEHTEKGAVTALDIATLTEDQKSLRRD  704
            + MF +P + ++ W E G+EG+ +FL RV R          +T+ +I+   E+  +L + 
Sbjct  636  YEMFMGPLDASIAWSEEGLEGSRKFLDRVYR---------LITTKEIT--EENSGALDKV  684

Query  705  LHKTIAKVTDDIGRRQTFNTAIAAIMELMNKLAKAPQESDQDRALTQETLLAVVRMLYPF  764
             + T+  VT+++++ + FNTAIA +M ++N        ++++  L  +   + V+++ PF
Sbjct  685  YNETVKAVTEQVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPF  736

Query  765  TPHVCFTLWQALQGEGD-VDTAPWPVADENAMVEDSKLVVVQVNGKVRGKITVAADASEE  823
            +PH+   LWQAL + G+ +   PWP  DE+ +VE+   +VVQ++GKV++K+ VA D S E
Sbjct  737  APHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSRE  796

Query  824  QVRERAAQEPLVAKYLDGVTVRKVIYVPGKLLNLVV  859
            +++E A  +  V   + G  + KVI VP KL+N+V+
Sbjct  797  ELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

1331) leuS in NC_012582


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  532 bits (2007),  Expect = 5e-152, Method: Compositional matrix adjust.
 Identities = 373/867 (44%), Positives = 560/867 (65%), Gaps = 50/867 (5%)

Query  41   YNPQDIEHKVQQHWDNNKTFVVSEDPNKEKFYCLSMFPYPSGR-LHMGHVRNYTIGDVVS  99
            Y+   IE K Q  W +N TF  + D++K KFY L MFPYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  100  RFQRLQGKNVLQPIGWDAFGLPAENAAVKNNTAPAPWTYENIEYMKNQLKLLGFGYDWNR  159
            RF+R QG NVL+P+GWDAFGLPAE+ A+     PA  T ENI   K Q++ LGF+YDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  160  EFATCRPEYYRWEQEFFTKLFAKGLVYKKTSSVNWCPNDQTVLANEQV-EDGCCWRCDTP  218
            E  T  P+YY+W Q +FTKL+ KGL Y    +VNW  +  T +ANE+V  DG   R + P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  219  VEQKEIPQWFIKITAYAQELLDDLDNLDGWPEMVKTMQRNWIGRSEGVELKFAVKGENTD  278
            V +K + QW +KITAYA+ LL+DL+++D WPE +K MQRNWIG+S G ++ F VK+ + D
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  279  LEVYTTRPDTLMGVTYVGIAAGHplatkaaannpalaaFIDECKNTKVAEAEIA----TM  334
            + V+TTRPDTL G TY  +A+ H+L    ++++ A A  + + K      +++A    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEA--VADYKRQASLKSDLARTDLAK  300

Query  335  EKKGMATGLTAIHPLNGREVPIYIANFVLMDYGTGAVMAVPAHDQRDFEFATKYGLDIIP  394
            EK G+ TG  AI+P+NG+E+P+ IA++VL  YGTGA+MAVPAHD+RD EFA ++ LDIIP
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  395  VIKPADGSELDVSEAAYTEKGVLFASGEFDGLDFQAAFNaiaakleaegkgkkTVNFRLR  454
            V+  +     +V EAA+TE G+ + S+ +DGLD  +A+  +   LEAEG G+  V +RLR
Sbjct  361  VLEGG-----NVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  455  DWGVSRQRYWGAPIPMVTTEDGQVHPVPADQLPVILP--EDVVMDGVT-SPIKADKEWAK  511
            DW  SRQRYWG PIP++  EDG   +VP  +LP++LP   D+   G   SP+    +W  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  512  TTF-NGEPALRETDTFDTFMESSWYYARYCSPQADDIL-DPEKANYWLPVDQYIGGIEHA  569
             T  +G  + RET+T      SSWYY RY  P+  + L D E  + WLPVD Y+GG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  570  CMHLLYSRFFYKLLRDAGYVKSDEPFKKLLCQGMVLADAFYYTNDKGGKEWVSPTEVKVE  629
             +HLLY+RF  K+L D G V + EPF+KL+ QGM+L+ +  Y + +G+   + +T+    
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS--YRDSRGA---LVATDKVEK  590

Query  630  RDGKGRIVSAVDATGRQVEHSGMIKMSKSKNNGIDPQEMVDKYGADTVRLFMMFASPADM  689
            RDG    V     TG ++E++   KMSKS +N ++P+++V++YGADT+R++ MF +P D 
Sbjct  591  RDGSFFHV----ETGEELEQAP-AKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  690  TLEWQESGVEGANRFLRRVWKLVREHTELGQAPALDASALNADQKALRRDVHKTIAKVTD  749
            ++ W E G+EG+ +FL RV +L+       + ++           AL +  + T+  VT+
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLITTKEITEENSG-----------ALDKVYNETVKAVTE  694

Query  750  DVARRQTFNTAIAAIMELMNKLTKAPMTEAQDRAILDEALKAITLMLYPITPHICFEMWV  809
            +V + + FNTAIA +M ++N       +  ++  ++ +  K++  ++ P++PH+  E+W 
Sbjct  695  QVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  810  ALGQS--NIDTASWPTYDEAALVEDEKLIVLQVNGKLRGKLTVAADATQQQVEALGMQDE  867
            AL  S  +I   +WP+YDE+ LVE++  IV+Q++GK+++KL VA D ++++++ +++ +E
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  868  NVQKFIDGLTVRKVIYVPGKLLNIVAN  894
            +VQ  I G  + KVI VP KL+NIV +
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVIK  833

1332) leuS in NC_009457


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  532 bits (2007),  Expect = 5e-152, Method: Compositional matrix adjust.
 Identities = 373/867 (44%), Positives = 560/867 (65%), Gaps = 50/867 (5%)

Query  41   YNPQDIEHKVQQHWDNNKTFVVSEDPNKEKFYCLSMFPYPSGR-LHMGHVRNYTIGDVVS  99
            Y+   IE K Q  W +N TF  + D++K KFY L MFPYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  100  RFQRLQGKNVLQPIGWDAFGLPAENAAVKNNTAPAPWTYENIEYMKNQLKLLGFGYDWNR  159
            RF+R QG NVL+P+GWDAFGLPAE+ A+     PA  T ENI   K Q++ LGF+YDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  160  EFATCRPEYYRWEQEFFTKLFAKGLVYKKTSSVNWCPNDQTVLANEQV-EDGCCWRCDTP  218
            E  T  P+YY+W Q +FTKL+ KGL Y    +VNW  +  T +ANE+V  DG   R + P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  219  VEQKEIPQWFIKITAYAQELLDDLDNLDGWPEMVKTMQRNWIGRSEGVELKFAVKGENTD  278
            V +K + QW +KITAYA+ LL+DL+++D WPE +K MQRNWIG+S G ++ F VK+ + D
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  279  LEVYTTRPDTLMGVTYVGIAAGHplatkaaannpalaaFIDECKNTKVAEAEIA----TM  334
            + V+TTRPDTL G TY  +A+ H+L    ++++ A A  + + K      +++A    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEA--VADYKRQASLKSDLARTDLAK  300

Query  335  EKKGMATGLTAIHPLNGREVPIYIANFVLMDYGTGAVMAVPAHDQRDFEFATKYGLDIIP  394
            EK G+ TG  AI+P+NG+E+P+ IA++VL  YGTGA+MAVPAHD+RD EFA ++ LDIIP
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  395  VIKPADGSELDVSEAAYTEKGVLFASGEFDGLDFQAAFNaiaakleaegkgkkTVNFRLR  454
            V+  +     +V EAA+TE G+ + S+ +DGLD  +A+  +   LEAEG G+  V +RLR
Sbjct  361  VLEGG-----NVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  455  DWGVSRQRYWGAPIPMVTTEDGQVHPVPADQLPVILP--EDVVMDGVT-SPIKADKEWAK  511
            DW  SRQRYWG PIP++  EDG   +VP  +LP++LP   D+   G   SP+    +W  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  512  TTF-NGEPALRETDTFDTFMESSWYYARYCSPQADDIL-DPEKANYWLPVDQYIGGIEHA  569
             T  +G  + RET+T      SSWYY RY  P+  + L D E  + WLPVD Y+GG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  570  CMHLLYSRFFYKLLRDAGYVKSDEPFKKLLCQGMVLADAFYYTNDKGGKEWVSPTEVKVE  629
             +HLLY+RF  K+L D G V + EPF+KL+ QGM+L+ +  Y + +G+   + +T+    
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS--YRDSRGA---LVATDKVEK  590

Query  630  RDGKGRIVSAVDATGRQVEHSGMIKMSKSKNNGIDPQEMVDKYGADTVRLFMMFASPADM  689
            RDG    V     TG ++E++   KMSKS +N ++P+++V++YGADT+R++ MF +P D 
Sbjct  591  RDGSFFHV----ETGEELEQAP-AKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  690  TLEWQESGVEGANRFLRRVWKLVREHTELGQAPALDASALNADQKALRRDVHKTIAKVTD  749
            ++ W E G+EG+ +FL RV +L+       + ++           AL +  + T+  VT+
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLITTKEITEENSG-----------ALDKVYNETVKAVTE  694

Query  750  DVARRQTFNTAIAAIMELMNKLTKAPMTEAQDRAILDEALKAITLMLYPITPHICFEMWV  809
            +V + + FNTAIA +M ++N       +  ++  ++ +  K++  ++ P++PH+  E+W 
Sbjct  695  QVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  810  ALGQS--NIDTASWPTYDEAALVEDEKLIVLQVNGKLRGKLTVAADATQQQVEALGMQDE  867
            AL  S  +I   +WP+YDE+ LVE++  IV+Q++GK+++KL VA D ++++++ +++ +E
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  868  NVQKFIDGLTVRKVIYVPGKLLNIVAN  894
            +VQ  I G  + KVI VP KL+NIV +
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVIK  833

1333) SU5_01339 in NC_017623


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  532 bits (2006),  Expect = 5e-152, Method: Compositional matrix adjust.
 Identities = 362/866 (42%), Positives = 552/866 (64%), Gaps = 48/866 (5%)

Query  36   YRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVVA  94
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  95   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKTLGFGYDWSR  154
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q+++LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  155  EIATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  213
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  214  VERKEIPQWFIKITAYADELLRDLDKLDHWPDTVKTMQRNWIGRSEGVEITFDVKGYDNT  273
            V RK + QW +KITAYA+ LL DL+ +D WP+++K MQRNWIG+S G ++TF VK+ D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  274  LTVYTTRPDTFMGATYLAVAAGHPlaqkaaannaelaaFIDECRNTKVAEAEMA----TM  329
            +TV+TTRPDT+ GATY  +A+ H+L +  ++++   A  + + +      +++A    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEA--VADYKRQASLKSDLARTDLAK  300

Query  330  EKKGVDTGYKAIHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLTIKP  389
            EK GV TG  AI+P+ G E+PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L I P
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  390  VILAADGSEPDLSEQALTEKGVLFNSGEFDGLAFEAAFNAIADKLAEKGVGERKVNYRLR  449
            V+        ++ E A+TE G+ +NS+ +DGL   +A+  + + L   GVG+ +V YRLR
Sbjct  361  VL-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  450  DWGVSRQRYWGAPIPMVTLEDGTVLPTPEDQLPVILP--EDVVMDGIT-SPIKADPEWAK  506
            DW  SRQRYWG PIP++  EDGT  + PE +LP++LP   D+   G   SP+    +W  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  507  TT-VNGMPALRETDTFDTFMESSWYYARYTCPQYQEGMLDSKAANYWLPVDIYIGGIEHA  565
             T  +G+ + RET+T      SSWYY RY  P+  E + D    + WLPVDIY+GG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  566  IMHLLYFRFFHKLMRDAGMVTSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVE  625
            ++HLLY RF HK++ D G+V + EP ++L+ QGM+L+ ++      + R  + + D +  
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEK  590

Query  626  RDEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADM  685
            RD  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D 
Sbjct  591  RD--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  686  TLEWQESGVEGANRFIKRVWKLVYEHTAKGPVAALNVDALSEDQKALRRDVHKTIAKVTD  745
            ++ W E G+EG+ +F+ RV +L+   T+K        +   E+  AL +  + T+  VT+
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLI---TTK--------EITEENSGALDKVYNETVKAVTE  694

Query  746  DIGRRQTFNTAIAAIMELMNKLAKAPQEGEQDRALLQEALQAVVRMLNPFTPHVCFTLWQ  805
            ++++ + FNTAIA +M ++N        ++++  L+ +  ++ V+++ PF+PH+   LWQ
Sbjct  695  QVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  806  ELGGEGD-IDNAPWPVADEQAMVENTTLVVVQVNGKVRGKITVAVDATEEQVRERAGQEH  864
             L + G+ I   PWP  DE  +VEN   +VVQ++GKV++K+ VA D + E+++E A  ++
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  865  LVAKYLDGVTVRKVIYVPGKLLNLVV  890
             V   + G  + KVI VP KL+N+V+
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVI  832

1334) leuS in NC_017317


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  531 bits (2003),  Expect = 1e-151, Method: Compositional matrix adjust.
 Identities = 356/742 (48%), Positives = 511/742 (69%), Gaps = 68/742 (9%)

Query  234  LVYRSNSTVNWCPGLGTVLANEEVTADGRSERGNFPVFRKNLSQWMMRITAYSDRLIDDL  293
            L Y ++  VNW   LGT +ANEEV +DG SERG +PV RK + QWM++ITAY++RL++DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  294  EVLDWPEKVKSMQRNWIGRSRGAEVDFET--AGKTITVFTTRPDTLFGASYMVLAPEHEL  351
            E +DWPE +K MQRNWIG+S GA+V F    ++K +TVFTTRPDTLFGA+Y VLAPEH L
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  352  VDALVAAGTGSYEGIDARWTFGEadpasavaayrasiaaksDLERQE-NKEKTGVFLGVY  410
            VDA+ +++ +  E++                 Y+   + KSDL R +  KEKTGV  G Y
Sbjct  268  VDAITTSDQA--EAVAD---------------YKRQASLKSDLARTDLAKEKTGVWTGSY  310

Query  411  ATNPVNGEQIPVFIGDYVLTGYGTGAIMSVPAHDARDYEFATEFGLPIREVVAGGDVNVG  470
            A NPVNG ++PV I+DYVL++YGTGAIM+VPAHD RD EFA +F L I  V+ GG+V+ +
Sbjct  311  AINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEA  370

Query  471  PYVEPGTAINSANDRGLDIDGLDKAEAIARVIEWLEAQGAGVEKIQYKLRDWLFARQRYW  530
            ++ E G  INS       +DGLDKA AIA+++EWLEA+G G E++ Y+LRDWLF+RQRYW
Sbjct  371  AFTEDGLHINSDF-----LDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYW  425

Query  531  GEPFPVVYDEDGVAHALPESMLPVELPEVEDYKPVSFDPDDADSEPQPPLAKATEWTTVE  590
            GEP+P++  EDG + A+PES LP+ LP   D +P         +  ++PLA+ T+W  +E
Sbjct  426  GEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTDW--LE  475

Query  591  LDLGDGPKTYTRDTNVMPQWAGSSWYQLRYIDPTNSEQFCDIENERYWTGPRGENdlggv  650
            +   DG K   R+TN MPQWAGSSWY LRYIDP N+E++ D E  + W           V
Sbjct  476  VTREDGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLP---------V  525

Query  651  dlyvggvEHAVLHLLYSRFWHKVLFDLGYVTSGEPYRRLFNQGYIQAFAYTDSRGVYVPA  710
            D+YVGG EHAVLHLLY+RFWHKVL+DLG V + EP+++LFNQG I + +Y DSRG  V++
Sbjct  526  DIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVAT  585

Query  711  AEVEEKDGKFFY--NGEEVNQEYGKMGKSLKNAVAPDEICSDFGADTLRVYEMAMGPLDT  768
              VE +DG FF    GEE++Q  +KM+KSLKN V PD++  ++GADTLRVYEM MGPLD+
Sbjct  586  DKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  769  SRPWATKDVIGAHRFLQRLWRLVVNEETGELSVTDASLTNDDLKALNRTIAGIRDDYQGL  828
            S +W+  ++ G+++FL+R+ RL+   E  E     ++L     K  N T+ ++ ++ + +
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLITTKEITE--ENSGALD----KVYNETVKAVTEQVDQM  699

Query  829  RINTVVAKAIEYVNYLTK------TYSKGAPREAVEPLAIMVAPVAPHIAEELWKRL-GH  881
            ++NT +A+ + +VN   K       Y+KG        +  ++AP APH++EELW+ L + 
Sbjct  700  KFNTAIAQLMVFVNAANKEDKLFSDYAKG--------FVQLIAPFAPHLGEELWQALTAS  751

Query  882  EETITFEQFPSYEEKWLKDDEVELPVQINGKVRARIMVPTDATQDQIVEIALAEPTVQSH  941
             E+I++   PSY+E  L +++VE+ VQI+GKV+A+++V+ D +++++ E+ALA+  VQ++
Sbjct  752  GESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAE  811

Query  942  LEGKNLFKQIVVPGRMVNLVIK  963
            + GK+++K I VP ++VN+VIK
Sbjct  812  IAGKDIIKVIAVPNKLVNIVIK  833


 Score =  139 bits (511),  Expect = 8e-34, Method: Compositional matrix adjust.
 Identities = 80/149 (54%), Positives = 101/149 (68%), Gaps = 10/149 (6%)

Query  34   GDIERTWQKFWIDNGTFNAPNPVGDLAVTEQKLPEDKLFVQDMFPYPSGAGLHVGHPLGY  93
              IE  WQ FW DN TF++    +            K++  DMFPYPSGAGLHVGHP GY
Sbjct  7    TAIEPKWQAFWADNHTFKTGTDASK----------PKFYALDMFPYPSGAGLHVGHPEGY  56

Query  94   IATDVYARFNRMLGKNVLHTLGYDAFGLPAEQYAIQTGTHPRTTTMANIENMRRQLGALG  153
             ATD+ +RF+R  G NVLH +G DAFGLPAEQYA++TG +P   T  NI N +RQ+ ALG
Sbjct  57   TATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALG  116

Query  154  LGHDTRRSVATTDPEFYKWTQWIFLKIFN  182
            ++ D  R V TTDP++YKWTQWIF K+++
Sbjct  117  FSYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1335) leuS in NC_011149


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  531 bits (2002),  Expect = 1e-151, Method: Compositional matrix adjust.
 Identities = 362/866 (42%), Positives = 552/866 (64%), Gaps = 48/866 (5%)

Query  5    YRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVVA  63
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKTLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q+++LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EIATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADELLRDLDKLDHWPDTVKTMQRNWIGRSEGVEITFDVKGYDNT  242
            V RK + QW +KITAYA+ LL DL+ +D WP+++K MQRNWIG+S G ++TF VK+ D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGATYLAVAAGHPlaqkaaannaelaaFIDECRNTKVAEAEMA----TM  298
            +TV+TTRPDT+ GATY  +A+ H+L +  ++++   A  + + +      +++A    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEA--VADYKRQASLKSDLARTDLAK  300

Query  299  EKKGVDTGYKAIHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLTIKP  358
            EK GV TG  AI+P+ G E+PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L I P
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VILAADGSEPDLSEQALTEKGVLFNSGEFDGLAFEAAFNAIADKLAEKGVGERKVNYRLR  418
            V+        ++ E A+TE G+ +NS+ +DGL   +A+  + + L   GVG+ +V YRLR
Sbjct  361  VL-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  419  DWGVSRQRYWGAPIPMVTLEDGTVLPTPEDQLPVILP--EDVVMDGIT-SPIKADPEWAK  475
            DW  SRQRYWG PIP++  EDGT  + PE +LP++LP   D+   G   SP+    +W  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  476  TT-VNGMPALRETDTFDTFMESSWYYARYTCPQYQEGMLDSKAANYWLPVDIYIGGIEHA  534
             T  +G+ + RET+T      SSWYY RY  P+  E + D    + WLPVDIY+GG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  535  IMHLLYFRFFHKLMRDAGMVTSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVE  594
            ++HLLY RF HK++ D G+V + EP ++L+ QGM+L+ ++      + R  + + D +  
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEK  590

Query  595  RDEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADM  654
            RD  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D 
Sbjct  591  RD--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  655  TLEWQESGVEGANRFIKRVWKLVYEHTAKGPVAALNVDALSEDQKALRRDVHKTIAKVTD  714
            ++ W E G+EG+ +F+ RV +L+   T+K        +   E+  AL +  + T+  VT+
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLI---TTK--------EITEENSGALDKVYNETVKAVTE  694

Query  715  DIGRRQTFNTAIAAIMELMNKLAKAPQEGEQDRALLQEALQAVVRMLNPFTPHVCFTLWQ  774
            ++++ + FNTAIA +M ++N        ++++  L+ +  ++ V+++ PF+PH+   LWQ
Sbjct  695  QVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  775  ELGGEGD-IDNAPWPVADEQAMVENTTLVVVQVNGKVRGKITVAVDATEEQVRERAGQEH  833
             L + G+ I   PWP  DE  +VEN   +VVQ++GKV++K+ VA D + E+++E A  ++
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  834  LVAKYLDGVTVRKVIYVPGKLLNLVV  859
             V   + G  + KVI VP KL+N+V+
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVI  832

1336) leuS in NC_021844


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  531 bits (2002),  Expect = 1e-151, Method: Compositional matrix adjust.
 Identities = 362/866 (42%), Positives = 552/866 (64%), Gaps = 48/866 (5%)

Query  5    YRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVVA  63
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKTLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q+++LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EIATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADELLRDLDKLDHWPDTVKTMQRNWIGRSEGVEITFDVKGYDNT  242
            V RK + QW +KITAYA+ LL DL+ +D WP+++K MQRNWIG+S G ++TF VK+ D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGATYLAVAAGHPlaqkaaannaelaaFIDECRNTKVAEAEMA----TM  298
            +TV+TTRPDT+ GATY  +A+ H+L +  ++++   A  + + +      +++A    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEA--VADYKRQASLKSDLARTDLAK  300

Query  299  EKKGVDTGYKAIHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLTIKP  358
            EK GV TG  AI+P+ G E+PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L I P
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VILAADGSEPDLSEQALTEKGVLFNSGEFDGLAFEAAFNAIADKLAEKGVGERKVNYRLR  418
            V+        ++ E A+TE G+ +NS+ +DGL   +A+  + + L   GVG+ +V YRLR
Sbjct  361  VL-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  419  DWGVSRQRYWGAPIPMVTLEDGTVLPTPEDQLPVILP--EDVVMDGIT-SPIKADPEWAK  475
            DW  SRQRYWG PIP++  EDGT  + PE +LP++LP   D+   G   SP+    +W  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  476  TT-VNGMPALRETDTFDTFMESSWYYARYTCPQYQEGMLDSKAANYWLPVDIYIGGIEHA  534
             T  +G+ + RET+T      SSWYY RY  P+  E + D    + WLPVDIY+GG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  535  IMHLLYFRFFHKLMRDAGMVTSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVE  594
            ++HLLY RF HK++ D G+V + EP ++L+ QGM+L+ ++      + R  + + D +  
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEK  590

Query  595  RDEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADM  654
            RD  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D 
Sbjct  591  RD--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  655  TLEWQESGVEGANRFIKRVWKLVYEHTAKGPVAALNVDALSEDQKALRRDVHKTIAKVTD  714
            ++ W E G+EG+ +F+ RV +L+   T+K        +   E+  AL +  + T+  VT+
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLI---TTK--------EITEENSGALDKVYNETVKAVTE  694

Query  715  DIGRRQTFNTAIAAIMELMNKLAKAPQEGEQDRALLQEALQAVVRMLNPFTPHVCFTLWQ  774
            ++++ + FNTAIA +M ++N        ++++  L+ +  ++ V+++ PF+PH+   LWQ
Sbjct  695  QVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  775  ELGGEGD-IDNAPWPVADEQAMVENTTLVVVQVNGKVRGKITVAVDATEEQVRERAGQEH  833
             L + G+ I   PWP  DE  +VEN   +VVQ++GKV++K+ VA D + E+++E A  ++
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  834  LVAKYLDGVTVRKVIYVPGKLLNLVV  859
             V   + G  + KVI VP KL+N+V+
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVI  832

1337) SBOV06001 in NC_022241


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  531 bits (2002),  Expect = 1e-151, Method: Compositional matrix adjust.
 Identities = 362/866 (42%), Positives = 552/866 (64%), Gaps = 48/866 (5%)

Query  5    YRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVVA  63
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKTLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q+++LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EIATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADELLRDLDKLDHWPDTVKTMQRNWIGRSEGVEITFDVKGYDNT  242
            V RK + QW +KITAYA+ LL DL+ +D WP+++K MQRNWIG+S G ++TF VK+ D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGATYLAVAAGHPlaqkaaannaelaaFIDECRNTKVAEAEMA----TM  298
            +TV+TTRPDT+ GATY  +A+ H+L +  ++++   A  + + +      +++A    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEA--VADYKRQASLKSDLARTDLAK  300

Query  299  EKKGVDTGYKAIHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLTIKP  358
            EK GV TG  AI+P+ G E+PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L I P
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VILAADGSEPDLSEQALTEKGVLFNSGEFDGLAFEAAFNAIADKLAEKGVGERKVNYRLR  418
            V+        ++ E A+TE G+ +NS+ +DGL   +A+  + + L   GVG+ +V YRLR
Sbjct  361  VL-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  419  DWGVSRQRYWGAPIPMVTLEDGTVLPTPEDQLPVILP--EDVVMDGIT-SPIKADPEWAK  475
            DW  SRQRYWG PIP++  EDGT  + PE +LP++LP   D+   G   SP+    +W  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  476  TT-VNGMPALRETDTFDTFMESSWYYARYTCPQYQEGMLDSKAANYWLPVDIYIGGIEHA  534
             T  +G+ + RET+T      SSWYY RY  P+  E + D    + WLPVDIY+GG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  535  IMHLLYFRFFHKLMRDAGMVTSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVE  594
            ++HLLY RF HK++ D G+V + EP ++L+ QGM+L+ ++      + R  + + D +  
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEK  590

Query  595  RDEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADM  654
            RD  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D 
Sbjct  591  RD--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  655  TLEWQESGVEGANRFIKRVWKLVYEHTAKGPVAALNVDALSEDQKALRRDVHKTIAKVTD  714
            ++ W E G+EG+ +F+ RV +L+   T+K        +   E+  AL +  + T+  VT+
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLI---TTK--------EITEENSGALDKVYNETVKAVTE  694

Query  715  DIGRRQTFNTAIAAIMELMNKLAKAPQEGEQDRALLQEALQAVVRMLNPFTPHVCFTLWQ  774
            ++++ + FNTAIA +M ++N        ++++  L+ +  ++ V+++ PF+PH+   LWQ
Sbjct  695  QVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  775  ELGGEGD-IDNAPWPVADEQAMVENTTLVVVQVNGKVRGKITVAVDATEEQVRERAGQEH  833
             L + G+ I   PWP  DE  +VEN   +VVQ++GKV++K+ VA D + E+++E A  ++
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  834  LVAKYLDGVTVRKVIYVPGKLLNLVV  859
             V   + G  + KVI VP KL+N+V+
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVI  832

1338) leuS in NC_021818


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  531 bits (2002),  Expect = 1e-151, Method: Compositional matrix adjust.
 Identities = 362/866 (42%), Positives = 552/866 (64%), Gaps = 48/866 (5%)

Query  5    YRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVVA  63
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKTLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q+++LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EIATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADELLRDLDKLDHWPDTVKTMQRNWIGRSEGVEITFDVKGYDNT  242
            V RK + QW +KITAYA+ LL DL+ +D WP+++K MQRNWIG+S G ++TF VK+ D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGATYLAVAAGHPlaqkaaannaelaaFIDECRNTKVAEAEMA----TM  298
            +TV+TTRPDT+ GATY  +A+ H+L +  ++++   A  + + +      +++A    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEA--VADYKRQASLKSDLARTDLAK  300

Query  299  EKKGVDTGYKAIHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLTIKP  358
            EK GV TG  AI+P+ G E+PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L I P
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VILAADGSEPDLSEQALTEKGVLFNSGEFDGLAFEAAFNAIADKLAEKGVGERKVNYRLR  418
            V+        ++ E A+TE G+ +NS+ +DGL   +A+  + + L   GVG+ +V YRLR
Sbjct  361  VL-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  419  DWGVSRQRYWGAPIPMVTLEDGTVLPTPEDQLPVILP--EDVVMDGIT-SPIKADPEWAK  475
            DW  SRQRYWG PIP++  EDGT  + PE +LP++LP   D+   G   SP+    +W  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  476  TT-VNGMPALRETDTFDTFMESSWYYARYTCPQYQEGMLDSKAANYWLPVDIYIGGIEHA  534
             T  +G+ + RET+T      SSWYY RY  P+  E + D    + WLPVDIY+GG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  535  IMHLLYFRFFHKLMRDAGMVTSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVE  594
            ++HLLY RF HK++ D G+V + EP ++L+ QGM+L+ ++      + R  + + D +  
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEK  590

Query  595  RDEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADM  654
            RD  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D 
Sbjct  591  RD--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  655  TLEWQESGVEGANRFIKRVWKLVYEHTAKGPVAALNVDALSEDQKALRRDVHKTIAKVTD  714
            ++ W E G+EG+ +F+ RV +L+   T+K        +   E+  AL +  + T+  VT+
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLI---TTK--------EITEENSGALDKVYNETVKAVTE  694

Query  715  DIGRRQTFNTAIAAIMELMNKLAKAPQEGEQDRALLQEALQAVVRMLNPFTPHVCFTLWQ  774
            ++++ + FNTAIA +M ++N        ++++  L+ +  ++ V+++ PF+PH+   LWQ
Sbjct  695  QVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  775  ELGGEGD-IDNAPWPVADEQAMVENTTLVVVQVNGKVRGKITVAVDATEEQVRERAGQEH  833
             L + G+ I   PWP  DE  +VEN   +VVQ++GKV++K+ VA D + E+++E A  ++
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  834  LVAKYLDGVTVRKVIYVPGKLLNLVV  859
             V   + G  + KVI VP KL+N+V+
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVI  832

1339) leuS in NC_021810


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  531 bits (2002),  Expect = 1e-151, Method: Compositional matrix adjust.
 Identities = 362/866 (42%), Positives = 552/866 (64%), Gaps = 48/866 (5%)

Query  5    YRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVVA  63
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKTLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q+++LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EIATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADELLRDLDKLDHWPDTVKTMQRNWIGRSEGVEITFDVKGYDNT  242
            V RK + QW +KITAYA+ LL DL+ +D WP+++K MQRNWIG+S G ++TF VK+ D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGATYLAVAAGHPlaqkaaannaelaaFIDECRNTKVAEAEMA----TM  298
            +TV+TTRPDT+ GATY  +A+ H+L +  ++++   A  + + +      +++A    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEA--VADYKRQASLKSDLARTDLAK  300

Query  299  EKKGVDTGYKAIHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLTIKP  358
            EK GV TG  AI+P+ G E+PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L I P
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VILAADGSEPDLSEQALTEKGVLFNSGEFDGLAFEAAFNAIADKLAEKGVGERKVNYRLR  418
            V+        ++ E A+TE G+ +NS+ +DGL   +A+  + + L   GVG+ +V YRLR
Sbjct  361  VL-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  419  DWGVSRQRYWGAPIPMVTLEDGTVLPTPEDQLPVILP--EDVVMDGIT-SPIKADPEWAK  475
            DW  SRQRYWG PIP++  EDGT  + PE +LP++LP   D+   G   SP+    +W  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  476  TT-VNGMPALRETDTFDTFMESSWYYARYTCPQYQEGMLDSKAANYWLPVDIYIGGIEHA  534
             T  +G+ + RET+T      SSWYY RY  P+  E + D    + WLPVDIY+GG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  535  IMHLLYFRFFHKLMRDAGMVTSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVE  594
            ++HLLY RF HK++ D G+V + EP ++L+ QGM+L+ ++      + R  + + D +  
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEK  590

Query  595  RDEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADM  654
            RD  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D 
Sbjct  591  RD--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  655  TLEWQESGVEGANRFIKRVWKLVYEHTAKGPVAALNVDALSEDQKALRRDVHKTIAKVTD  714
            ++ W E G+EG+ +F+ RV +L+   T+K        +   E+  AL +  + T+  VT+
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLI---TTK--------EITEENSGALDKVYNETVKAVTE  694

Query  715  DIGRRQTFNTAIAAIMELMNKLAKAPQEGEQDRALLQEALQAVVRMLNPFTPHVCFTLWQ  774
            ++++ + FNTAIA +M ++N        ++++  L+ +  ++ V+++ PF+PH+   LWQ
Sbjct  695  QVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  775  ELGGEGD-IDNAPWPVADEQAMVENTTLVVVQVNGKVRGKITVAVDATEEQVRERAGQEH  833
             L + G+ I   PWP  DE  +VEN   +VVQ++GKV++K+ VA D + E+++E A  ++
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  834  LVAKYLDGVTVRKVIYVPGKLLNLVV  859
             V   + G  + KVI VP KL+N+V+
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVI  832

1340) leuS in NC_021812


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  531 bits (2002),  Expect = 1e-151, Method: Compositional matrix adjust.
 Identities = 362/866 (42%), Positives = 552/866 (64%), Gaps = 48/866 (5%)

Query  5    YRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVVA  63
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKTLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q+++LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EIATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADELLRDLDKLDHWPDTVKTMQRNWIGRSEGVEITFDVKGYDNT  242
            V RK + QW +KITAYA+ LL DL+ +D WP+++K MQRNWIG+S G ++TF VK+ D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGATYLAVAAGHPlaqkaaannaelaaFIDECRNTKVAEAEMA----TM  298
            +TV+TTRPDT+ GATY  +A+ H+L +  ++++   A  + + +      +++A    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEA--VADYKRQASLKSDLARTDLAK  300

Query  299  EKKGVDTGYKAIHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLTIKP  358
            EK GV TG  AI+P+ G E+PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L I P
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VILAADGSEPDLSEQALTEKGVLFNSGEFDGLAFEAAFNAIADKLAEKGVGERKVNYRLR  418
            V+        ++ E A+TE G+ +NS+ +DGL   +A+  + + L   GVG+ +V YRLR
Sbjct  361  VL-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  419  DWGVSRQRYWGAPIPMVTLEDGTVLPTPEDQLPVILP--EDVVMDGIT-SPIKADPEWAK  475
            DW  SRQRYWG PIP++  EDGT  + PE +LP++LP   D+   G   SP+    +W  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  476  TT-VNGMPALRETDTFDTFMESSWYYARYTCPQYQEGMLDSKAANYWLPVDIYIGGIEHA  534
             T  +G+ + RET+T      SSWYY RY  P+  E + D    + WLPVDIY+GG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  535  IMHLLYFRFFHKLMRDAGMVTSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVE  594
            ++HLLY RF HK++ D G+V + EP ++L+ QGM+L+ ++      + R  + + D +  
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEK  590

Query  595  RDEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADM  654
            RD  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D 
Sbjct  591  RD--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  655  TLEWQESGVEGANRFIKRVWKLVYEHTAKGPVAALNVDALSEDQKALRRDVHKTIAKVTD  714
            ++ W E G+EG+ +F+ RV +L+   T+K        +   E+  AL +  + T+  VT+
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLI---TTK--------EITEENSGALDKVYNETVKAVTE  694

Query  715  DIGRRQTFNTAIAAIMELMNKLAKAPQEGEQDRALLQEALQAVVRMLNPFTPHVCFTLWQ  774
            ++++ + FNTAIA +M ++N        ++++  L+ +  ++ V+++ PF+PH+   LWQ
Sbjct  695  QVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  775  ELGGEGD-IDNAPWPVADEQAMVENTTLVVVQVNGKVRGKITVAVDATEEQVRERAGQEH  833
             L + G+ I   PWP  DE  +VEN   +VVQ++GKV++K+ VA D + E+++E A  ++
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  834  LVAKYLDGVTVRKVIYVPGKLLNLVV  859
             V   + G  + KVI VP KL+N+V+
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVI  832

1341) leuS in NC_011083


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  531 bits (2002),  Expect = 1e-151, Method: Compositional matrix adjust.
 Identities = 362/866 (42%), Positives = 552/866 (64%), Gaps = 48/866 (5%)

Query  5    YRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVVA  63
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKTLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q+++LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EIATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADELLRDLDKLDHWPDTVKTMQRNWIGRSEGVEITFDVKGYDNT  242
            V RK + QW +KITAYA+ LL DL+ +D WP+++K MQRNWIG+S G ++TF VK+ D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGATYLAVAAGHPlaqkaaannaelaaFIDECRNTKVAEAEMA----TM  298
            +TV+TTRPDT+ GATY  +A+ H+L +  ++++   A  + + +      +++A    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEA--VADYKRQASLKSDLARTDLAK  300

Query  299  EKKGVDTGYKAIHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLTIKP  358
            EK GV TG  AI+P+ G E+PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L I P
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VILAADGSEPDLSEQALTEKGVLFNSGEFDGLAFEAAFNAIADKLAEKGVGERKVNYRLR  418
            V+        ++ E A+TE G+ +NS+ +DGL   +A+  + + L   GVG+ +V YRLR
Sbjct  361  VL-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  419  DWGVSRQRYWGAPIPMVTLEDGTVLPTPEDQLPVILP--EDVVMDGIT-SPIKADPEWAK  475
            DW  SRQRYWG PIP++  EDGT  + PE +LP++LP   D+   G   SP+    +W  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  476  TT-VNGMPALRETDTFDTFMESSWYYARYTCPQYQEGMLDSKAANYWLPVDIYIGGIEHA  534
             T  +G+ + RET+T      SSWYY RY  P+  E + D    + WLPVDIY+GG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  535  IMHLLYFRFFHKLMRDAGMVTSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVE  594
            ++HLLY RF HK++ D G+V + EP ++L+ QGM+L+ ++      + R  + + D +  
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEK  590

Query  595  RDEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADM  654
            RD  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D 
Sbjct  591  RD--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  655  TLEWQESGVEGANRFIKRVWKLVYEHTAKGPVAALNVDALSEDQKALRRDVHKTIAKVTD  714
            ++ W E G+EG+ +F+ RV +L+   T+K        +   E+  AL +  + T+  VT+
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLI---TTK--------EITEENSGALDKVYNETVKAVTE  694

Query  715  DIGRRQTFNTAIAAIMELMNKLAKAPQEGEQDRALLQEALQAVVRMLNPFTPHVCFTLWQ  774
            ++++ + FNTAIA +M ++N        ++++  L+ +  ++ V+++ PF+PH+   LWQ
Sbjct  695  QVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  775  ELGGEGD-IDNAPWPVADEQAMVENTTLVVVQVNGKVRGKITVAVDATEEQVRERAGQEH  833
             L + G+ I   PWP  DE  +VEN   +VVQ++GKV++K+ VA D + E+++E A  ++
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  834  LVAKYLDGVTVRKVIYVPGKLLNLVV  859
             V   + G  + KVI VP KL+N+V+
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVI  832

1342) leuS in NC_011080


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  531 bits (2002),  Expect = 1e-151, Method: Compositional matrix adjust.
 Identities = 362/866 (42%), Positives = 552/866 (64%), Gaps = 48/866 (5%)

Query  5    YRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVVA  63
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKTLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q+++LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EIATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADELLRDLDKLDHWPDTVKTMQRNWIGRSEGVEITFDVKGYDNT  242
            V RK + QW +KITAYA+ LL DL+ +D WP+++K MQRNWIG+S G ++TF VK+ D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGATYLAVAAGHPlaqkaaannaelaaFIDECRNTKVAEAEMA----TM  298
            +TV+TTRPDT+ GATY  +A+ H+L +  ++++   A  + + +      +++A    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEA--VADYKRQASLKSDLARTDLAK  300

Query  299  EKKGVDTGYKAIHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLTIKP  358
            EK GV TG  AI+P+ G E+PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L I P
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VILAADGSEPDLSEQALTEKGVLFNSGEFDGLAFEAAFNAIADKLAEKGVGERKVNYRLR  418
            V+        ++ E A+TE G+ +NS+ +DGL   +A+  + + L   GVG+ +V YRLR
Sbjct  361  VL-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  419  DWGVSRQRYWGAPIPMVTLEDGTVLPTPEDQLPVILP--EDVVMDGIT-SPIKADPEWAK  475
            DW  SRQRYWG PIP++  EDGT  + PE +LP++LP   D+   G   SP+    +W  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  476  TT-VNGMPALRETDTFDTFMESSWYYARYTCPQYQEGMLDSKAANYWLPVDIYIGGIEHA  534
             T  +G+ + RET+T      SSWYY RY  P+  E + D    + WLPVDIY+GG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  535  IMHLLYFRFFHKLMRDAGMVTSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVE  594
            ++HLLY RF HK++ D G+V + EP ++L+ QGM+L+ ++      + R  + + D +  
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEK  590

Query  595  RDEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADM  654
            RD  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D 
Sbjct  591  RD--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  655  TLEWQESGVEGANRFIKRVWKLVYEHTAKGPVAALNVDALSEDQKALRRDVHKTIAKVTD  714
            ++ W E G+EG+ +F+ RV +L+   T+K        +   E+  AL +  + T+  VT+
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLI---TTK--------EITEENSGALDKVYNETVKAVTE  694

Query  715  DIGRRQTFNTAIAAIMELMNKLAKAPQEGEQDRALLQEALQAVVRMLNPFTPHVCFTLWQ  774
            ++++ + FNTAIA +M ++N        ++++  L+ +  ++ V+++ PF+PH+   LWQ
Sbjct  695  QVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  775  ELGGEGD-IDNAPWPVADEQAMVENTTLVVVQVNGKVRGKITVAVDATEEQVRERAGQEH  833
             L + G+ I   PWP  DE  +VEN   +VVQ++GKV++K+ VA D + E+++E A  ++
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  834  LVAKYLDGVTVRKVIYVPGKLLNLVV  859
             V   + G  + KVI VP KL+N+V+
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVI  832

1343) SN31241_16540 in NC_021902


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  531 bits (2002),  Expect = 1e-151, Method: Compositional matrix adjust.
 Identities = 362/866 (42%), Positives = 552/866 (64%), Gaps = 48/866 (5%)

Query  5    YRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVVA  63
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKTLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q+++LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EIATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADELLRDLDKLDHWPDTVKTMQRNWIGRSEGVEITFDVKGYDNT  242
            V RK + QW +KITAYA+ LL DL+ +D WP+++K MQRNWIG+S G ++TF VK+ D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGATYLAVAAGHPlaqkaaannaelaaFIDECRNTKVAEAEMA----TM  298
            +TV+TTRPDT+ GATY  +A+ H+L +  ++++   A  + + +      +++A    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEA--VADYKRQASLKSDLARTDLAK  300

Query  299  EKKGVDTGYKAIHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLTIKP  358
            EK GV TG  AI+P+ G E+PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L I P
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VILAADGSEPDLSEQALTEKGVLFNSGEFDGLAFEAAFNAIADKLAEKGVGERKVNYRLR  418
            V+        ++ E A+TE G+ +NS+ +DGL   +A+  + + L   GVG+ +V YRLR
Sbjct  361  VL-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  419  DWGVSRQRYWGAPIPMVTLEDGTVLPTPEDQLPVILP--EDVVMDGIT-SPIKADPEWAK  475
            DW  SRQRYWG PIP++  EDGT  + PE +LP++LP   D+   G   SP+    +W  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  476  TT-VNGMPALRETDTFDTFMESSWYYARYTCPQYQEGMLDSKAANYWLPVDIYIGGIEHA  534
             T  +G+ + RET+T      SSWYY RY  P+  E + D    + WLPVDIY+GG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  535  IMHLLYFRFFHKLMRDAGMVTSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVE  594
            ++HLLY RF HK++ D G+V + EP ++L+ QGM+L+ ++      + R  + + D +  
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEK  590

Query  595  RDEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADM  654
            RD  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D 
Sbjct  591  RD--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  655  TLEWQESGVEGANRFIKRVWKLVYEHTAKGPVAALNVDALSEDQKALRRDVHKTIAKVTD  714
            ++ W E G+EG+ +F+ RV +L+   T+K        +   E+  AL +  + T+  VT+
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLI---TTK--------EITEENSGALDKVYNETVKAVTE  694

Query  715  DIGRRQTFNTAIAAIMELMNKLAKAPQEGEQDRALLQEALQAVVRMLNPFTPHVCFTLWQ  774
            ++++ + FNTAIA +M ++N        ++++  L+ +  ++ V+++ PF+PH+   LWQ
Sbjct  695  QVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  775  ELGGEGD-IDNAPWPVADEQAMVENTTLVVVQVNGKVRGKITVAVDATEEQVRERAGQEH  833
             L + G+ I   PWP  DE  +VEN   +VVQ++GKV++K+ VA D + E+++E A  ++
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  834  LVAKYLDGVTVRKVIYVPGKLLNLVV  859
             V   + G  + KVI VP KL+N+V+
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVI  832

1344) leuS in NC_010102


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  531 bits (2003),  Expect = 1e-151, Method: Compositional matrix adjust.
 Identities = 362/866 (42%), Positives = 552/866 (64%), Gaps = 48/866 (5%)

Query  5    YRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVVA  63
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKTLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q+++LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EIATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADELLRDLDKLDHWPDTVKTMQRNWIGRSEGVEITFDVKGYDNT  242
            V RK + QW +KITAYA+ LL DL+ +D WP+++K MQRNWIG+S G ++TF VK+ D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGATYLAVAAGHPlaqkaaannaelaaFIDECRNTKVAEAEMA----TM  298
            +TV+TTRPDT+ GATY  +A+ H+L +  ++++   A  + + +      +++A    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEA--VADYKRQASLKSDLARTDLAK  300

Query  299  EKKGVDTGYKAIHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLTIKP  358
            EK GV TG  AI+P+ G E+PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L I P
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VILAADGSEPDLSEQALTEKGVLFNSGEFDGLAFEAAFNAIADKLAEKGVGERKVNYRLR  418
            V+        ++ E A+TE G+ +NS+ +DGL   +A+  + + L   GVG+ +V YRLR
Sbjct  361  VL-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  419  DWGVSRQRYWGAPIPMVTLEDGTVLPTPEDQLPVILP--EDVVMDGIT-SPIKADPEWAK  475
            DW  SRQRYWG PIP++  EDGT  + PE +LP++LP   D+   G   SP+    +W  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  476  TT-VNGMPALRETDTFDTFMESSWYYARYTCPQYQEGMLDSKAANYWLPVDIYIGGIEHA  534
             T  +G+ + RET+T      SSWYY RY  P+  E + D    + WLPVDIY+GG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  535  IMHLLYFRFFHKLMRDAGMVTSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVE  594
            ++HLLY RF HK++ D G+V + EP ++L+ QGM+L+ ++      + R  + + D +  
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEK  590

Query  595  RDEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADM  654
            RD  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D 
Sbjct  591  RD--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  655  TLEWQESGVEGANRFIKRVWKLVYEHTAKGSVAALNVDALSEDQKALRRDVHKTIAKVTD  714
            ++ W E G+EG+ +F+ RV +L+   T+K        +   E+  AL +  + T+  VT+
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLI---TTK--------EITEENSGALDKVYNETVKAVTE  694

Query  715  DIGRRQTFNTAIAAIMELMNKLAKAPQEGEQDRALLQEALQAVVRMLNPFTPHVCFTLWQ  774
            ++++ + FNTAIA +M ++N        ++++  L+ +  ++ V+++ PF+PH+   LWQ
Sbjct  695  QVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  775  ELGGEGD-IDNAPWPVADEQAMVENTTLVVVQVNGKVRGKITVAVDATEEQVRERAGQEH  833
             L + G+ I   PWP  DE  +VEN   +VVQ++GKV++K+ VA D + E+++E A  ++
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  834  LVAKYLDGVTVRKVIYVPGKLLNLVV  859
             V   + G  + KVI VP KL+N+V+
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVI  832

1345) leuS in NC_012125


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  531 bits (2002),  Expect = 1e-151, Method: Compositional matrix adjust.
 Identities = 362/866 (42%), Positives = 552/866 (64%), Gaps = 48/866 (5%)

Query  5    YRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVVA  63
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKTLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q+++LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EIATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADELLRDLDKLDHWPDTVKTMQRNWIGRSEGVEITFDVKGYDNT  242
            V RK + QW +KITAYA+ LL DL+ +D WP+++K MQRNWIG+S G ++TF VK+ D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGATYLAVAAGHPlaqkaaannaelaaFIDECRNTKVAEAEMA----TM  298
            +TV+TTRPDT+ GATY  +A+ H+L +  ++++   A  + + +      +++A    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEA--VADYKRQASLKSDLARTDLAK  300

Query  299  EKKGVDTGYKAIHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLTIKP  358
            EK GV TG  AI+P+ G E+PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L I P
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VILAADGSEPDLSEQALTEKGVLFNSGEFDGLAFEAAFNAIADKLAEKGVGERKVNYRLR  418
            V+        ++ E A+TE G+ +NS+ +DGL   +A+  + + L   GVG+ +V YRLR
Sbjct  361  VL-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  419  DWGVSRQRYWGAPIPMVTLEDGTVLPTPEDQLPVILP--EDVVMDGIT-SPIKADPEWAK  475
            DW  SRQRYWG PIP++  EDGT  + PE +LP++LP   D+   G   SP+    +W  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  476  TT-VNGMPALRETDTFDTFMESSWYYARYTCPQYQEGMLDSKAANYWLPVDIYIGGIEHA  534
             T  +G+ + RET+T      SSWYY RY  P+  E + D    + WLPVDIY+GG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  535  IMHLLYFRFFHKLMRDAGMVTSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVE  594
            ++HLLY RF HK++ D G+V + EP ++L+ QGM+L+ ++      + R  + + D +  
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEK  590

Query  595  RDEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADM  654
            RD  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D 
Sbjct  591  RD--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  655  TLEWQESGVEGANRFIKRVWKLVYEHTAKGPVAALNVDALSEDQKALRRDVHKTIAKVTD  714
            ++ W E G+EG+ +F+ RV +L+   T+K        +   E+  AL +  + T+  VT+
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLI---TTK--------EITEENSGALDKVYNETVKAVTE  694

Query  715  DIGRRQTFNTAIAAIMELMNKLAKAPQEGEQDRALLQEALQAVVRMLNPFTPHVCFTLWQ  774
            ++++ + FNTAIA +M ++N        ++++  L+ +  ++ V+++ PF+PH+   LWQ
Sbjct  695  QVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  775  ELGGEGD-IDNAPWPVADEQAMVENTTLVVVQVNGKVRGKITVAVDATEEQVRERAGQEH  833
             L + G+ I   PWP  DE  +VEN   +VVQ++GKV++K+ VA D + E+++E A  ++
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  834  LVAKYLDGVTVRKVIYVPGKLLNLVV  859
             V   + G  + KVI VP KL+N+V+
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVI  832

1346) leuS in NC_011094


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  531 bits (2003),  Expect = 1e-151, Method: Compositional matrix adjust.
 Identities = 362/866 (42%), Positives = 552/866 (64%), Gaps = 48/866 (5%)

Query  5    YRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVVA  63
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKTLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q+++LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EIATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADELLRDLDKLDHWPDTVKTMQRNWIGRSEGVEITFDVKGYDNT  242
            V RK + QW +KITAYA+ LL DL+ +D WP+++K MQRNWIG+S G ++TF VK+ D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGATYLAVAAGHPlaqkaaannaelaaFIDECRNTKVAEAEMA----TM  298
            +TV+TTRPDT+ GATY  +A+ H+L +  ++++   A  + + +      +++A    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEA--VADYKRQASLKSDLARTDLAK  300

Query  299  EKKGVDTGYKAIHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLTIKP  358
            EK GV TG  AI+P+ G E+PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L I P
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VILAADGSEPDLSEQALTEKGVLFNSGEFDGLAFEAAFNAIADKLAEKGVGERKVNYRLR  418
            V+        ++ E A+TE G+ +NS+ +DGL   +A+  + + L   GVG+ +V YRLR
Sbjct  361  VL-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  419  DWGVSRQRYWGAPIPMVTLEDGTVLPTPEDQLPVILP--EDVVMDGIT-SPIKADPEWAK  475
            DW  SRQRYWG PIP++  EDGT  + PE +LP++LP   D+   G   SP+    +W  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  476  TT-VNGMPALRETDTFDTFMESSWYYARYTCPQYQEGMLDSKAANYWLPVDIYIGGIEHA  534
             T  +G+ + RET+T      SSWYY RY  P+  E + D    + WLPVDIY+GG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  535  IMHLLYFRFFHKLMRDAGMVTSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVE  594
            ++HLLY RF HK++ D G+V + EP ++L+ QGM+L+ ++      + R  + + D +  
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEK  590

Query  595  RDEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADM  654
            RD  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D 
Sbjct  591  RD--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  655  TLEWQESGVEGANRFIKRVWKLVYEHTAKGSVAALNVDALSEDQKALRRDVHKTIAKVTD  714
            ++ W E G+EG+ +F+ RV +L+   T+K        +   E+  AL +  + T+  VT+
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLI---TTK--------EITEENSGALDKVYNETVKAVTE  694

Query  715  DIGRRQTFNTAIAAIMELMNKLAKAPQEGEQDRALLQEALQAVVRMLNPFTPHVCFTLWQ  774
            ++++ + FNTAIA +M ++N        ++++  L+ +  ++ V+++ PF+PH+   LWQ
Sbjct  695  QVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  775  ELGGEGD-IDNAPWPVADEQAMVENTTLVVVQVNGKVRGKITVAVDATEEQVRERAGQEH  833
             L + G+ I   PWP  DE  +VEN   +VVQ++GKV++K+ VA D + E+++E A  ++
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  834  LVAKYLDGVTVRKVIYVPGKLLNLVV  859
             V   + G  + KVI VP KL+N+V+
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVI  832

1347) leuS in NC_006905


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  531 bits (2005),  Expect = 6e-152, Method: Compositional matrix adjust.
 Identities = 362/866 (42%), Positives = 552/866 (64%), Gaps = 48/866 (5%)

Query  36   YRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVVA  94
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  95   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKTLGFGYDWSR  154
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q+++LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  155  EIATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  213
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  214  VERKEIPQWFIKITAYADELLRDLDKLDHWPDTVKTMQRNWIGRSEGVEITFDVKGYDNT  273
            V RK + QW +KITAYA+ LL DL+ +D WP+++K MQRNWIG+S G ++TF VK+ D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  274  LTVYTTRPDTFMGATYLAVAAGHPlaqkaaannaelaaFIDECRNTKVAEAEMA----TM  329
            +TV+TTRPDT+ GATY  +A+ H+L +  ++++   A  + + +      +++A    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEA--VADYKRQASLKSDLARTDLAK  300

Query  330  EKKGVDTGYKAIHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLTIKP  389
            EK GV TG  AI+P+ G E+PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L I P
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  390  VILAADSSEPDLSEQALTEKGVLFNSGEFDGLAFEAAFNAIADKLAEKGVGERKVNYRLR  449
            V+        ++ E A+TE G+ +NS+ +DGL   +A+  + + L   GVG+ +V YRLR
Sbjct  361  VL-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  450  DWGVSRQRYWGAPIPMVTLEDGTVLPTPEDQLPVILP--EDVVMDGIT-SPIKADPEWAK  506
            DW  SRQRYWG PIP++  EDGT  + PE +LP++LP   D+   G   SP+    +W  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  507  TT-VNGMPALRETDTFDTFMESSWYYARYTCPQYQEGMLDSKAANYWLPVDIYIGGIEHA  565
             T  +G+ + RET+T      SSWYY RY  P+  E + D    + WLPVDIY+GG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  566  IMHLLYFRFFHKLMRDAGMVTSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVE  625
            ++HLLY RF HK++ D G+V + EP ++L+ QGM+L+ ++      + R  + + D +  
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEK  590

Query  626  RDEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADM  685
            RD  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D 
Sbjct  591  RD--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  686  TLEWQESGVEGANRFIKRVWKLVYEHTAKGPVAALNVDALSEDQKALRRDVHKTIAKVTD  745
            ++ W E G+EG+ +F+ RV +L+   T+K        +   E+  AL +  + T+  VT+
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLI---TTK--------EITEENSGALDKVYNETVKAVTE  694

Query  746  DIGRRQTFNTAIAAIMELMNKLAKAPQEGEQDRALLQEALQAVVRMLNPFTPHVCFTLWQ  805
            ++++ + FNTAIA +M ++N        ++++  L+ +  ++ V+++ PF+PH+   LWQ
Sbjct  695  QVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  806  ELGGEGD-IDNAPWPVADEQAMVENTTLVVVQVNGKVRGKITVAVDATEEQVRERAGQEH  864
             L + G+ I   PWP  DE  +VEN   +VVQ++GKV++K+ VA D + E+++E A  ++
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  865  LVAKYLDGVTVRKVIYVPGKLLNLVV  890
             V   + G  + KVI VP KL+N+V+
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVI  832

1348) leuS in NC_009567


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  531 bits (2004),  Expect = 7e-152, Method: Compositional matrix adjust.
 Identities = 355/866 (41%), Positives = 557/866 (65%), Gaps = 46/866 (5%)

Query  5    YRPDMIEPKVQQYWVENKVFKAIKDESKEKYYCLSMFPYPSGR-LHMGHVRNYTIGDVIS  63
            Y    IEPK Q +W +N  FK+  D SK K+Y L MFPYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPFGWDAFGLPAEGAAIKNKTAPAKWTYENIAYMKKQLQLLGFGFDWDR  123
            R++R  G NVL+P GWDAFGLPAE  A+     PA  T ENIA  K+Q++ LGF++DWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EIATCKPEYYKWEQWFFTELYKKGLVYKKTSTVNWCPNDETVLANEQV-HEGCCWRCDTP  182
            E+ T  P+YYKW QW+FT LY KGL Y     VNW  +  T +ANE+V  +G   R + P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VEQKEIPQWFIKITDYAEQLLGGLDTLPQWPDMVKTMQRNWIGRSEGVEITFDVANTNEK  242
            V +K + QW +KIT YAE+LL +L+ + +WP+ +K MQRNWIG+S G ++TF V +T+  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  VAVYTTRPDTFYGVSY--LGIaaahplaslaaQNNPELAAFIQEAK-NAKVAEADLATME  299
             +V+TTRPDT++G +Y  L+   A   A  ++++   +A + ++A  ++ +A +DLA  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGMATGLFAIHPLTGEKLPIWVANFVLMHYGTGAVMAVPAHDQRDFEFAQKYSLPIKQV  359
            K G+ TG +AI+P+ G  +P+W+A++VL  YGTGA+MAVPAHD+RD EFA++++L   ++
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNL---DI  358

Query  360  IAPLADEEIDLTKQAFVEHGKLVNSAEFDGKDFDGAFNGIADKLEKLGVGKRQVNYRLRD  419
            I+ L + +++    AF E+G  +NS  +DG D  +A+  + + LE  GVG+ +V YRLRD
Sbjct  359  IPVLEGGNVE--EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMLTLENGDVVPAPMEDLPIILP--EDVVMDGV-KSPIKADPNWAKT  476
            W  SRQRYWG PIP++  E+G   + P  +LP++LP   D+   G   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  TL-NGTPALKETDTFDTFMESSWYYARYTCPQYQNGMLDAEEANYWLPVDQYIGGIEHAT  535
            T  +G  + +ET+T      SSWYY RY  P+  + + D E  + WLPVD Y+GG EHA 
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLLYFRFFHKLLRDAGFVTSEEPADKLLCQGMVLADAFYYTSPTNERIWVSPTQVTLER  595
            +HLLY RF HK+L D G V + EP +KL+ QGM+L+ ++      + R     + V+ ++
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSR----GALVATDK  587

Query  596  DEKGRIIKATDPEGRELVHSGMTKMSKSKNNGIDPQEMVEKYGADTVRLFMMFASPAEMT  655
             EK R     + E  E ++ + +KMSKS +N ++P+++VE+YGADT+R++ MF +P + +
Sbjct  588  VEK-RDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  656  LEWQESGVEGAKRFLGRVWNLVYQYQQNPAKTSLDITALSAEQKVLRREVHKTIAKVSDD  715
            + W E G+EG+++FL+RV  L+         T+ +IT    +   L +  + T+  V+++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLI---------TTKEITE--ENSGALDKVYNETVKAVTEQ  695

Query  716  IGRRQTFNTAIAAVMELMNKLTKAPLDSEQDRAVMAEALSAVVRMLYPITPHICFELWQA  775
            +++ + FNTAIA +M ++N        ++++  + ++   + V+++ P++PH+  ELWQA
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  776  L-GNESAIDTAEWVKADEAAMVEDEKLIVVQVNGKVRGKVTVAADADEDTVKTIAFADEN  834
            L ++  +I    W   DE+ +VE++  IVVQ++GKV++K+ VA D   + ++ +A+A+E+
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  835  VKKFIDNQHIVKVIYVVGKLLNVVVK  860
            V+  I  ++I+KVI V  KL+N+V+K
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVIK  833

1349) leuS in NC_022221


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  531 bits (2003),  Expect = 8e-152, Method: Compositional matrix adjust.
 Identities = 363/866 (42%), Positives = 551/866 (64%), Gaps = 48/866 (5%)

Query  5    YRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVVA  63
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKTLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q+++LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EIATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADELLRDLDKLDHWPDTVKTMQRNWIGRSEGVEITFDVKGYDNT  242
            V RK + QW +KITAYA+ LL DL+ +D WP+++K MQRNWIG+S G ++TF VK+ D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGATYLAVAAGHPlaqkaaannaelaaFIDECRNTKVAEAEMA----TM  298
            +TV+TTRPDT+ GATY  +A+ H+L +  ++++   A  + + +      +++A    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEA--VADYKRQASLKSDLARTDLAK  300

Query  299  EKKGVDTGFKATHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLTIKP  358
            EK GV TG  A +P+ G E+PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L I P
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VILAADGSEPDLSEQALTEKGVLFNSGEFDGLAFEAAFNAIADKLAEKGVGERKVNYRLR  418
            V+        ++ E A+TE G+ +NS+ +DGL   +A+  + + L   GVG+ +V YRLR
Sbjct  361  VL-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  419  DWGVSRQRYWGAPIPMVTLEDGTVLPTPEDQLPVILP--EDVVMDGIT-SPIKADPEWAK  475
            DW  SRQRYWG PIP++  EDGT  + PE +LP++LP   D+   G   SP+    +W  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  476  TT-VNGMPALRETDTFDTFMESSWYYARYTCPQYQEGMLDSKAANYWLPVDIYIGGIEHA  534
             T  +G+ + RET+T      SSWYY RY  P+  E + D    + WLPVDIY+GG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  535  IMHLLYFRFFHKLMRDAGMVTSDEPAKKLLCQGMVLADAFYYVGENGERNWVSPVDAIVE  594
            ++HLLY RF HK++ D G+V + EP +KL+ QGM+L+ ++      + R  + + D +  
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEK  590

Query  595  RDEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADM  654
            RD  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D 
Sbjct  591  RD--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  655  TLEWQESGVEGANRFIKRVWKLVYEHTAKGPVAALNVDALSEDQKALRRDVHKTIAKVTD  714
            ++ W E G+EG+ +F+ RV +L+   T+K        +   E+  AL +  + T+  VT+
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLI---TTK--------EITEENSGALDKVYNETVKAVTE  694

Query  715  DVGRRQTFNTAIAAIMELMNKLAKAPQEGEQDRALLQEALQAVVRMLNPFTPHVCFTLWQ  774
            +V++ + FNTAIA +M ++N        ++++  L+ +  ++ V+++ PF+PH+   LWQ
Sbjct  695  QVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  775  ELGGEGD-IDNAPWPVADEQAMVENTTLVVVQVNGKVRGKITVAVDATEEQVRERAGQEH  833
             L + G+ I   PWP  DE  +VEN   +VVQ++GKV++K+ VA D + E+++E A  ++
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  834  LVAKYLDGVTVRKVIYVPGKLLNLVV  859
             V   + G  + KVI VP KL+N+V+
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVI  832

1350) leuS in NC_016831


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  531 bits (2003),  Expect = 8e-152, Method: Compositional matrix adjust.
 Identities = 363/866 (42%), Positives = 551/866 (64%), Gaps = 48/866 (5%)

Query  5    YRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVVA  63
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKTLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q+++LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EIATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADELLRDLDKLDHWPDTVKTMQRNWIGRSEGVEITFDVKGYDNT  242
            V RK + QW +KITAYA+ LL DL+ +D WP+++K MQRNWIG+S G ++TF VK+ D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGATYLAVAAGHPlaqkaaannaelaaFIDECRNTKVAEAEMA----TM  298
            +TV+TTRPDT+ GATY  +A+ H+L +  ++++   A  + + +      +++A    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEA--VADYKRQASLKSDLARTDLAK  300

Query  299  EKKGVDTGFKATHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLTIKP  358
            EK GV TG  A +P+ G E+PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L I P
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VILAADGSEPDLSEQALTEKGVLFNSGEFDGLAFEAAFNAIADKLAEKGVGERKVNYRLR  418
            V+        ++ E A+TE G+ +NS+ +DGL   +A+  + + L   GVG+ +V YRLR
Sbjct  361  VL-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  419  DWGVSRQRYWGAPIPMVTLEDGTVLPTPEDQLPVILP--EDVVMDGIT-SPIKADPEWAK  475
            DW  SRQRYWG PIP++  EDGT  + PE +LP++LP   D+   G   SP+    +W  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  476  TT-VNGMPALRETDTFDTFMESSWYYARYTCPQYQEGMLDSKAANYWLPVDIYIGGIEHA  534
             T  +G+ + RET+T      SSWYY RY  P+  E + D    + WLPVDIY+GG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  535  IMHLLYFRFFHKLMRDAGMVTSDEPAKKLLCQGMVLADAFYYVGENGERNWVSPVDAIVE  594
            ++HLLY RF HK++ D G+V + EP +KL+ QGM+L+ ++      + R  + + D +  
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEK  590

Query  595  RDEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADM  654
            RD  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D 
Sbjct  591  RD--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  655  TLEWQESGVEGANRFIKRVWKLVYEHTAKGPVAALNVDALSEDQKALRRDVHKTIAKVTD  714
            ++ W E G+EG+ +F+ RV +L+   T+K        +   E+  AL +  + T+  VT+
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLI---TTK--------EITEENSGALDKVYNETVKAVTE  694

Query  715  DVGRRQTFNTAIAAIMELMNKLAKAPQEGEQDRALLQEALQAVVRMLNPFTPHVCFTLWQ  774
            +V++ + FNTAIA +M ++N        ++++  L+ +  ++ V+++ PF+PH+   LWQ
Sbjct  695  QVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  775  ELGGEGD-IDNAPWPVADEQAMVENTTLVVVQVNGKVRGKITVAVDATEEQVRERAGQEH  833
             L + G+ I   PWP  DE  +VEN   +VVQ++GKV++K+ VA D + E+++E A  ++
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  834  LVAKYLDGVTVRKVIYVPGKLLNLVV  859
             V   + G  + KVI VP KL+N+V+
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVI  832

1351) leuS in NC_017046


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  531 bits (2004),  Expect = 8e-152, Method: Compositional matrix adjust.
 Identities = 361/866 (42%), Positives = 552/866 (64%), Gaps = 48/866 (5%)

Query  86   YRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVVA  144
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  145  RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKTLGFGYDWSR  204
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q+++LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  205  EIATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  263
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  264  VERKEIPQWFIKITAYADELLRDLDKLDHWPDTVKTMQRNWIGRSEGVEITFDVKGYDNT  323
            V RK + QW +KITAYA+ LL DL+ +D WP+++K MQRNWIG+S G ++TF VK+ D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  324  LTVYTTRPDTFMGATYLAVAAGHPlaqkaaannaelaaFIDECRNTKVAEAEMA----TM  379
            +TV+TTRPDT+ GATY  +A+ H+L +  ++++   A  + + +      +++A    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEA--VADYKRQASLKSDLARTDLAK  300

Query  380  EKKGVDTGYKAIHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLTIKP  439
            EK GV TG  AI+P+ G E+PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L I P
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  440  VILAADGSEPDLSEQALTEKGVLFNSGEFDGLAFEAAFNAIADKLAEKGVGERKVNYRLR  499
            V+        ++ E A+TE G+ +NS+ +DGL   +A+  + + L   GVG+ +V YRLR
Sbjct  361  VL-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  500  DWGVSRQRYWGAPIPMVTLEDGTVLPTPEDQLPVILP--EDVVMDGIT-SPIKADPEWAK  556
            DW  SRQRYWG PIP++  EDGT  + PE +LP++LP   D+   G   SP+    +W  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  557  TT-VNGMPALRETDTFDTFMESSWYYARYTCPQYQEGMLDSKAANYWLPVDIYIGGIEHA  615
             T  +G+ + RET+T      SSWYY RY  P+  E + D    + WLPVDIY+GG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  616  IMHLLYFRFFHKLMRDAGMVTSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVE  675
            ++HLLY RF HK++ D G+V + EP ++L+ QGM+L+ ++      + R  + + D +  
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEK  590

Query  676  RDEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADM  735
            RD  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D 
Sbjct  591  RD--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  736  TLEWQESGVEGANRFIKRVWKLVYEHTAKGPVAALNVDALSEDQKALRRDVHKTIAKVTD  795
            ++ W E G+EG+ +F+ RV +L+   T+K        +   E+  AL +  + T+  VT+
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLI---TTK--------EITEENSGALDKVYNETVKAVTE  694

Query  796  DIGRRQTFNTAIAAIMELMNKLAKAPQEGEQDRALLQEALQAVVRMLNPFTPHVCFTLWQ  855
            ++++ + FNTAIA +M ++N        ++++  L+ +  ++ V+++ PF+PH+   LWQ
Sbjct  695  QVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  856  ELGGEGD-IDNAPWPVADEQAMVENTTLVVVQVNGKVRGKITVPVDATEEQVRERAGQEH  914
             L + G+ I   PWP  DE  +VEN   +VVQ++GKV++K+ V+ D + E+++E A  ++
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  915  LVAKYLDGVTVRKVIYVPGKLLNLVV  940
             V   + G  + KVI VP KL+N+V+
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVI  832

1352) leuS in NC_016857


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  531 bits (2004),  Expect = 8e-152, Method: Compositional matrix adjust.
 Identities = 361/866 (42%), Positives = 552/866 (64%), Gaps = 48/866 (5%)

Query  86   YRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVVA  144
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  145  RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKTLGFGYDWSR  204
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q+++LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  205  EIATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  263
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  264  VERKEIPQWFIKITAYADELLRDLDKLDHWPDTVKTMQRNWIGRSEGVEITFDVKGYDNT  323
            V RK + QW +KITAYA+ LL DL+ +D WP+++K MQRNWIG+S G ++TF VK+ D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  324  LTVYTTRPDTFMGATYLAVAAGHPlaqkaaannaelaaFIDECRNTKVAEAEMA----TM  379
            +TV+TTRPDT+ GATY  +A+ H+L +  ++++   A  + + +      +++A    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEA--VADYKRQASLKSDLARTDLAK  300

Query  380  EKKGVDTGYKAIHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLTIKP  439
            EK GV TG  AI+P+ G E+PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L I P
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  440  VILAADGSEPDLSEQALTEKGVLFNSGEFDGLAFEAAFNAIADKLAEKGVGERKVNYRLR  499
            V+        ++ E A+TE G+ +NS+ +DGL   +A+  + + L   GVG+ +V YRLR
Sbjct  361  VL-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  500  DWGVSRQRYWGAPIPMVTLEDGTVLPTPEDQLPVILP--EDVVMDGIT-SPIKADPEWAK  556
            DW  SRQRYWG PIP++  EDGT  + PE +LP++LP   D+   G   SP+    +W  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  557  TT-VNGMPALRETDTFDTFMESSWYYARYTCPQYQEGMLDSKAANYWLPVDIYIGGIEHA  615
             T  +G+ + RET+T      SSWYY RY  P+  E + D    + WLPVDIY+GG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  616  IMHLLYFRFFHKLMRDAGMVTSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVE  675
            ++HLLY RF HK++ D G+V + EP ++L+ QGM+L+ ++      + R  + + D +  
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEK  590

Query  676  RDEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADM  735
            RD  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D 
Sbjct  591  RD--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  736  TLEWQESGVEGANRFIKRVWKLVYEHTAKGPVAALNVDALSEDQKALRRDVHKTIAKVTD  795
            ++ W E G+EG+ +F+ RV +L+   T+K        +   E+  AL +  + T+  VT+
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLI---TTK--------EITEENSGALDKVYNETVKAVTE  694

Query  796  DIGRRQTFNTAIAAIMELMNKLAKAPQEGEQDRALLQEALQAVVRMLNPFTPHVCFTLWQ  855
            ++++ + FNTAIA +M ++N        ++++  L+ +  ++ V+++ PF+PH+   LWQ
Sbjct  695  QVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  856  ELGGEGD-IDNAPWPVADEQAMVENTTLVVVQVNGKVRGKITVPVDATEEQVRERAGQEH  914
             L + G+ I   PWP  DE  +VEN   +VVQ++GKV++K+ V+ D + E+++E A  ++
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  915  LVAKYLDGVTVRKVIYVPGKLLNLVV  940
             V   + G  + KVI VP KL+N+V+
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVI  832

1353) leuS in NC_016012


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  531 bits (2003),  Expect = 9e-152, Method: Compositional matrix adjust.
 Identities = 349/848 (42%), Positives = 531/848 (63%), Gaps = 59/848 (6%)

Query  9    IDKDSQKFWEDQEISKFDLNNEKEKLYVLEMFSYPSGSNLHAGHWFNFGLVDSYARYKKM  68
            I+   Q FW D++  K + +  K K+Y L+MF+YPSG+ LH GH   +   D  +R+K+ 
Sbjct  9    IEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSRFKRA  68

Query  69   SGFNVFQPMGFDAFGLPAENYAIKTGIHPKDSTMKNIDTMRLQLKKMGALFNFENEVVTC  128
             G NV++PMG DAFGLPAE+YA+ TG +P + T  NI   + Q++ +G  ++ + EV T 
Sbjct  69   QGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDREVNTT  128

Query  129  TPDYYKWTQWIFLKLYENNLAYRENAPVNFCPSCNTVLANEQVI-DNCCERCSTEIEKKN  187
             P+YYKWTQWIF KLYE+ LAY  + PVN      T +ANE+V+ D   ER +  + +K 
Sbjct  129  DPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKP  188

Query  188  LTQWFFKITNYADELVNKLDSLDWPDKTKSMQKNWIGRSFGTIVNFSIDNSNKNFNVFTT  247
            + QW +KIT YA+ L++ L+ +DWP+  K MQ+NWIG+S G+ V F + +++K+F VFTT
Sbjct  189  MRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTT  248

Query  248  RVDTLMGVSYVVLAPEHNLVLEITTKDNLNKVKNYIEESSKQSEIDRLSSSREKTGVFTG  307
            R DTL G +Y VLAPEH LV  ITT D+ + V +Y  ++S +S++ R   ++EKTGV TG
Sbjct  249  RPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTG  308

Query  308  SYAIHPITNKKIPIWISNYVISTYGTGAVMAVPAHDERDFEFATKFNLPINKVITNNKED  367
            SYAI+P+  K +P+WI++YV+++YGTGA+MAVPAHDERD EFA +FNL I  V+   + +
Sbjct  309  SYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVE  368

Query  368  ELPMTKKGVLINSLQFNSLSSDEAKDKITKYLESIGKGSFKTTFRLRDWLISRQRYWGAP  427
            E + T  G+ INS  +++L    A  K+   LE+ G G+ + T+RLRDWL+SRQRYWG P
Sbjct  369  EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEP  428

Query  428  IPIVHCDDCGIVPVPYTSLPVELPY--NIKFNANGKSPLEECSEFKETTCPKCNKKAKRE  485
            IPI+H +D    +VP + LP+ LP   +I+ ++ G SPL + ++  E T      K++RE
Sbjct  429  IPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGV-KGRRE  487

Query  486  TDTLDTFVCSSWYYLRYVDPKNNDAPFDSNKVNKMLPVDKYVGGPEHACMHLLYARFITK  545
            T+T+     SSWYYLRY+DP N +   D + +++ LPVD YVGG+EHA +HLLYARF  K
Sbjct  488  TNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWHK  547

Query  546  ALRDMGYLNFDEPFTSLTHQGLILGP-------------------DGF------------  574
             L D+G +   EPF  L +QG+ILG                    ++F            
Sbjct  548  VLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEELEQA  607

Query  575  --KMSKSRGNTISPDKYIEEYGSDVFRVYLMFAFTYTEGGAWSDDGIKSICKFINRSERL  632
              KMSKS  N ++PD  +E+YG+D +RVY MF      + AWS++G+ +  KF++R  RL
Sbjct  608  PAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRL  667

Query  633  INKSLDILRNKNFIFDYDKEAHEELLFALNTSIKMITSDIEQLQFNTCIAHFMKLTNQFS  692
            I              +   E    L    N ++K +T +++Q++FNT IA++M       
Sbjct  668  ITTK-----------EITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLM-------  709

Query  693  KYLNTNKITYDVLKDLLLNYLKIFAPFAPHFSEYYFGIVKELDNEAKTSVFLEEYPKADE  752
             ++N+ +    ++ D    +++++APFAPH++E    + + L   + +  ++   P  DE
Sbjct  710  VFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGE---ELWQALTASGESISYV-PWPSYDE  765

Query  753  KYLTRDQVEIAIQINGKIKTKIYVDTNSSEEEiknislsnndiinnitgktivkviviQN  812
              L  ++VEI +QI+GK+K+K+ V  + S EE+++++L+N+ +  +I+GK I+KVI + N
Sbjct  766  SKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPN  825

Query  813  RLVNIVVK  820
            +LVNIV+K
Sbjct  826  KLVNIVIK  833

1354) leuS in NC_009778


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  531 bits (2003),  Expect = 9e-152, Method: Compositional matrix adjust.
 Identities = 356/866 (42%), Positives = 547/866 (64%), Gaps = 48/866 (5%)

Query  5    YRPEEIESKVQLHWEEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIA  63
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNINYMKNQLKMLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NI   K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCTPEYYRWEQQFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKTMQRNWIGRSEGVEITFDVQNSDEK  242
            V RK + QW +KITAYA+ LL+DL+ +D WP+++K MQRNWIG+S G ++TF V+++D  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGVTYlavaaghplaqaaaaanpalGDFIAECRNTKVAEADMA----TM  298
            +TV+TTRPDT+ G TY     +   A   A + +  ++ +A+ +      +D+A    + 
Sbjct  243  FTVFTTRPDTLFGATY--AVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  299  EKKGVDTGLKAIHPLTGEAIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFATKYSLPIKP  358
            EK GV TG  AI+P+ G  +PVW A++VL  YGTGA+MAVP+HD+RD EFA +++L I P
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VILTAEGTAPDLSEQALTEKGVLFNSGEFDGLDFEAAFNAIADKLAAKGVGERKVNYRLR  418
            V+      + ++ E A+TE G+ +NS+ +DGLD  +A+  + + L A GVG+ +V YRLR
Sbjct  361  VL-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  419  DWGVSRQRYWGAPIPMVTLEDGTVMPTPADQLPVILP--EDVVMDGIT-SPIKADPEWAK  475
            DW  SRQRYWG PIP++  EDGT  + P  +LP++LP   D+   G   SP+    +W  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  476  TT-VNGQPALRETDTFDTFMESSWYYARYTCPQYKEGMLDEKAANYWLPVDIYIGGIEHA  534
             T  +G  + RET+T      SSWYY RY  P+  E + DE   + WLPVDIY+GG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  535  IMHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGANGERNWVSPKDAIVE  594
            ++HLLY RF HK++ D G+V + EP ++L+ QGM+L+ +  Y ++ G    + + D +  
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS--YRDSRGA---LVATDKVEK  590

Query  595  RDEKGRIVKASDAAGHELVYTGMSKMSKSKNNGIDPQEMVERYGADTVRLFMMFASPADM  654
            RD     V +++   +     + +KMSKS +N ++P+++VE+YGADT+R++ MF +P D 
Sbjct  591  RDGSFFHVETGEELEQ-----APAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  655  TLEWQESGVEGANRFLKRVWRLVYEHTSLGDAPALNVDALNDDQKALRRDVHKTIAKVSD  714
            ++ W E G+EG+ +FL RV RL+              +  +++  AL +  + T+  V++
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLI-----------TTKEITEENSGALDKVYNETVKAVTE  694

Query  715  DIGRRQTFNTAIAAIMELMNKLAKAPQEGEQDRALMREALLAVVRMLNPFTPHVSFTLWQ  774
            ++++ + FNTAIA +M ++N        ++++  L  +   + V+++ PF+PH++  LWQ
Sbjct  695  QVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  775  ELKGEGD-IDNAPWPQADDSAMVEDTTLVVVQVNGKVRGKITVAADATEEQVRERAAQEH  833
             L + G+ I   PWP  D+S +VE+   +VVQ++GKV++K+ VA D + E+++E A  ++
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  834  LVAKYLAGVTVRKVIYVPGKLLNLVV  859
             V   +AG  + KVI VP KL+N+V+
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVI  832

1355) leuS in NC_017933


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  531 bits (2003),  Expect = 9e-152, Method: Compositional matrix adjust.
 Identities = 356/866 (42%), Positives = 547/866 (64%), Gaps = 48/866 (5%)

Query  5    YRPEEIESKVQLHWEEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIA  63
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNINYMKNQLKMLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NI   K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCTPEYYRWEQQFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKTMQRNWIGRSEGVEITFDVQNSDEK  242
            V RK + QW +KITAYA+ LL+DL+ +D WP+++K MQRNWIG+S G ++TF V+++D  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGVTYlavaaghplaqaaaaanpalGDFIAECRNTKVAEADMA----TM  298
            +TV+TTRPDT+ G TY     +   A   A + +  ++ +A+ +      +D+A    + 
Sbjct  243  FTVFTTRPDTLFGATY--AVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  299  EKKGVDTGLKAIHPLTGEAIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFATKYSLPIKP  358
            EK GV TG  AI+P+ G  +PVW A++VL  YGTGA+MAVP+HD+RD EFA +++L I P
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VILTAEGTAPDLSEQALTEKGVLFNSGEFDGLDFEAAFNAIADKLAAKGVGERKVNYRLR  418
            V+      + ++ E A+TE G+ +NS+ +DGLD  +A+  + + L A GVG+ +V YRLR
Sbjct  361  VL-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  419  DWGVSRQRYWGAPIPMVTLEDGTVMPTPADQLPVILP--EDVVMDGIT-SPIKADPEWAK  475
            DW  SRQRYWG PIP++  EDGT  + P  +LP++LP   D+   G   SP+    +W  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  476  TT-VNGQPALRETDTFDTFMESSWYYARYTCPQYKEGMLDEKAANYWLPVDIYIGGIEHA  534
             T  +G  + RET+T      SSWYY RY  P+  E + DE   + WLPVDIY+GG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  535  IMHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGANGERNWVSPKDAIVE  594
            ++HLLY RF HK++ D G+V + EP ++L+ QGM+L+ +  Y ++ G    + + D +  
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS--YRDSRGA---LVATDKVEK  590

Query  595  RDEKGRIVKASDAAGHELVYTGMSKMSKSKNNGIDPQEMVERYGADTVRLFMMFASPADM  654
            RD     V +++   +     + +KMSKS +N ++P+++VE+YGADT+R++ MF +P D 
Sbjct  591  RDGSFFHVETGEELEQ-----APAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  655  TLEWQESGVEGANRFLKRVWRLVYEHTSLGDAPALNVDALNDDQKALRRDVHKTIAKVSD  714
            ++ W E G+EG+ +FL RV RL+              +  +++  AL +  + T+  V++
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLI-----------TTKEITEENSGALDKVYNETVKAVTE  694

Query  715  DIGRRQTFNTAIAAIMELMNKLAKAPQEGEQDRALMREALLAVVRMLNPFTPHVSFTLWQ  774
            ++++ + FNTAIA +M ++N        ++++  L  +   + V+++ PF+PH++  LWQ
Sbjct  695  QVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  775  ELKGEGD-IDNAPWPQADDSAMVEDTTLVVVQVNGKVRGKITVAADATEEQVRERAAQEH  833
             L + G+ I   PWP  D+S +VE+   +VVQ++GKV++K+ VA D + E+++E A  ++
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  834  LVAKYLAGVTVRKVIYVPGKLLNLVV  859
             V   +AG  + KVI VP KL+N+V+
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVI  832

1356) leuS in NC_020260


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  531 bits (2003),  Expect = 9e-152, Method: Compositional matrix adjust.
 Identities = 356/866 (42%), Positives = 547/866 (64%), Gaps = 48/866 (5%)

Query  5    YRPEEIESKVQLHWEEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIA  63
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNINYMKNQLKMLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NI   K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCTPEYYRWEQQFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKTMQRNWIGRSEGVEITFDVQNSDEK  242
            V RK + QW +KITAYA+ LL+DL+ +D WP+++K MQRNWIG+S G ++TF V+++D  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGVTYlavaaghplaqaaaaanpalGDFIAECRNTKVAEADMA----TM  298
            +TV+TTRPDT+ G TY     +   A   A + +  ++ +A+ +      +D+A    + 
Sbjct  243  FTVFTTRPDTLFGATY--AVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  299  EKKGVDTGLKAIHPLTGEAIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFATKYSLPIKP  358
            EK GV TG  AI+P+ G  +PVW A++VL  YGTGA+MAVP+HD+RD EFA +++L I P
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VILTAEGTAPDLSEQALTEKGVLFNSGEFDGLDFEAAFNAIADKLAAKGVGERKVNYRLR  418
            V+      + ++ E A+TE G+ +NS+ +DGLD  +A+  + + L A GVG+ +V YRLR
Sbjct  361  VL-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  419  DWGVSRQRYWGAPIPMVTLEDGTVMPTPADQLPVILP--EDVVMDGIT-SPIKADPEWAK  475
            DW  SRQRYWG PIP++  EDGT  + P  +LP++LP   D+   G   SP+    +W  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  476  TT-VNGQPALRETDTFDTFMESSWYYARYTCPQYKEGMLDEKAANYWLPVDIYIGGIEHA  534
             T  +G  + RET+T      SSWYY RY  P+  E + DE   + WLPVDIY+GG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  535  IMHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGANGERNWVSPKDAIVE  594
            ++HLLY RF HK++ D G+V + EP ++L+ QGM+L+ +  Y ++ G    + + D +  
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS--YRDSRGA---LVATDKVEK  590

Query  595  RDEKGRIVKASDAAGHELVYTGMSKMSKSKNNGIDPQEMVERYGADTVRLFMMFASPADM  654
            RD     V +++   +     + +KMSKS +N ++P+++VE+YGADT+R++ MF +P D 
Sbjct  591  RDGSFFHVETGEELEQ-----APAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  655  TLEWQESGVEGANRFLKRVWRLVYEHTSLGDAPALNVDALNDDQKALRRDVHKTIAKVSD  714
            ++ W E G+EG+ +FL RV RL+              +  +++  AL +  + T+  V++
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLI-----------TTKEITEENSGALDKVYNETVKAVTE  694

Query  715  DIGRRQTFNTAIAAIMELMNKLAKAPQEGEQDRALMREALLAVVRMLNPFTPHVSFTLWQ  774
            ++++ + FNTAIA +M ++N        ++++  L  +   + V+++ PF+PH++  LWQ
Sbjct  695  QVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  775  ELKGEGD-IDNAPWPQADDSAMVEDTTLVVVQVNGKVRGKITVAADATEEQVRERAAQEH  833
             L + G+ I   PWP  D+S +VE+   +VVQ++GKV++K+ VA D + E+++E A  ++
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  834  LVAKYLAGVTVRKVIYVPGKLLNLVV  859
             V   +AG  + KVI VP KL+N+V+
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVI  832

1357) DND132_1681 in NC_016803


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  531 bits (2003),  Expect = 9e-152, Method: Compositional matrix adjust.
 Identities = 356/866 (42%), Positives = 539/866 (63%), Gaps = 76/866 (8%)

Query  6    YSPEDIEKKWQAIWKESGCFQVETDPSRPKYYVLEMFPYPSGK-IHMGHVRNYSIGDVVA  64
            Y    IE KWQA+W ++  F+  TD+S+PK+Y L+MFPYPSG  +H+GH   Y+  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  65   RFKTMQGFNVLHPMGWDAFGLPAENAAIKHETHPATWTYQNIAEMRAQLKRLGYSYDWRR  124
            RFK  QG NVLHPMGWDAFGLPAE+ A+    +PA  T +NIA+ + Q++ LG+SYDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  125  EIATCRPEYYKWEQMFFLRFLEKGLAYRKDSPQNWCPTCNTVLANEQV-EDGLCWRCDTE  183
            E+ T  P+YYKW Q +F ++ EKGLAY  + P NW     T +ANE+V  DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  184  VEQKDMEQWFLRITdyadelladldsleGGWPERVLTMQRNWIGKSYGAELTFQVKDMDA  243
            V +K M QW L+IT YA+ LL DL+ +  +WPE +  MQRNWIGKS GA++TF+VKD D 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV--DWPESIKDMQRNWIGKSTGANVTFKVKDTDK  241

Query  244  TIDVFTTRPDTLYGATFMSVAAEHPMVEKFIADAPNKGEIEAFVTNIRNMDRIKRGADDL  303
             + VFTTRPDTL+GAT+  +A+EH++V+  I+ + +   +  +  +      + R     
Sbjct  242  DFTVFTTRPDTLFGATYAVLAPEHALVDA-ITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  304  EKEGVFTGKYCVNPVTGRDLPIYVANFVLMGYGTGAVMAVPAHDQRDFEFATKYKLPMQA  363
            EK GV TG Y +NPV G+++P+ +A++VL +YGTGA+MAVPAHD+RD EFA +++L + +
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  364  VINPPELQAKGEKLDAANLTEAYTAPGFLIHSGEFDGMPNEDAKKAIVEHLDKSGKGKMA  423
            V++  +++             A+T  G+ I+S+ +DG+ +  A   +VE L+  G G+  
Sbjct  361  VLEGGNVEE-----------AAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNEN  409

Query  424  VNYRLRDWNVSRQRFWGAPIPVIYCDDCGVVPVPEKDLPILLPENAQVRKDGK--SPLPT  481
            V YRLRDW  SRQR+WG PIP+I  +D    +VPE +LP++LP   ++R  G   SPL+ 
Sbjct  410  VTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLAN  469

Query  482  MEEFVNCTCPKCGKPARRETDTFDTFFESSWYYMRYCDPRNETEALGAEHLNYWMNVDQY  541
            + + ++ T     K +RRET+T      SSWYY+RY DP+N     + E L+ W+ VD Y
Sbjct  470  VTDWLEVTREDGVK-GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIY  528

Query  542  IGGIEHAILHLLYSRFFTKALRDCGYVTNSEPFANLLTQGMVL-----------------  584
            +GG EHA+LHLLY+RF  K L D G V   EPF +L+ QGM+L                 
Sbjct  529  VGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKV  588

Query  585  --KDG---------------GKMSKSKGNVVDPNAMINQYGADATRLFILFASPPVKELE  627
              +DG               +KMSKS  NVV+P+ +++QYGAD+ R++ +F +P    + 
Sbjct  589  EKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIA  648

Query  628  WSDQGIDGAYRFLSRLWRLVEELEDVLTPMMPGSHDKPANDAAKGLRFKEHDTIRRTTRD  687
            WS++G++G+ +FL R+ RL+   E  +T   +G+ DK  N++ K++             +
Sbjct  649  WSEEGLEGSRKFLDRVYRLITTKE--ITEENSGALDKVYNETVKAV------------TE  694

Query  688  IENEFQFNTVIAAIMELVNELYQVKDELKETDPAALSSAIATAVTLLSPVAPHICEELWA  747
              ++ +FNT IA +M +VN          + +   +S      V L++P APH+ EELW 
Sbjct  695  QVDQMKFNTAIAQLMVFVNA--------ANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  748  ALGHTVH-LTAQPWPTFDEKALVLDEVTLVVQVNGKVRGKFEAPNNAPQAEVEKLAMDLE  806
            AL  + + ++  PWP++DE  LV ++V +VVQ++GKV++K+  +++ ++ E++ +A+  E
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  807  NVQKFMEGKTVRKVIVIPNKLVNIVV  832
            +VQ  + GK + KVI +PNKLVNIV+
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVI  832

1358) leuS in NC_020307


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  531 bits (2003),  Expect = 9e-152, Method: Compositional matrix adjust.
 Identities = 362/866 (42%), Positives = 552/866 (64%), Gaps = 48/866 (5%)

Query  5    YRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVVA  63
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKTLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q+++LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EIATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADELLRDLDKLDHWPDTVKTMQRNWIGRSEGVEITFDVKGYDNT  242
            V RK + QW +KITAYA+ LL DL+ +D WP+++K MQRNWIG+S G ++TF VK+ D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGATYLAVAAGHPlaqkaaannaelaaFIDECRNTKVAEAEMA----TM  298
            +TV+TTRPDT+ GATY  +A+ H+L +  ++++   A  + + +      +++A    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEA--VADYKRQASLKSDLARTDLAK  300

Query  299  EKKGVDTGFKAIHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLTIKP  358
            EK GV TG  AI+P+ G E+PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L I P
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VILAADGSEPDLSEQALTEKGVLFNSGEFDGLAFEAAFNAIADKLAEKGVGERKVNYRLR  418
            V+        ++ E A+TE G+ +NS+ +DGL   +A+  + + L   GVG+ +V YRLR
Sbjct  361  VL-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  419  DWGVSRQRYWGAPIPMVTLEDGTVLPTPEDQLPVILP--EDVVMDGIT-SPIKADPEWAK  475
            DW  SRQRYWG PIP++  EDGT  + PE +LP++LP   D+   G   SP+    +W  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  476  TT-VNGMPALRETDTFDTFMESSWYYARYTCPQYQEGMLDSKAANYWLPVDIYIGGIEHA  534
             T  +G+ + RET+T      SSWYY RY  P+  E + D    + WLPVDIY+GG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  535  IMHLLYFRFFHKLMRDAGMVTSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVE  594
            ++HLLY RF HK++ D G+V + EP ++L+ QGM+L+ ++      + R  + + D +  
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEK  590

Query  595  RDEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADM  654
            RD  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D 
Sbjct  591  RD--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  655  TLEWQESGVEGANRFIKRVWKLVYEHTAKGPVAALNVDALSEDQKALRRDVHKTIAKVTD  714
            ++ W E G+EG+ +F+ RV +L+   T+K        +   E+  AL +  + T+  VT+
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLI---TTK--------EITEENSGALDKVYNETVKAVTE  694

Query  715  DIGRRQTFNTAIAAIMELMNKLAKAPQEGEQDRALLQEALQAVVRMLNPFTPHVCFTLWQ  774
            ++++ + FNTAIA +M ++N        ++++  L+ +  ++ V+++ PF+PH+   LWQ
Sbjct  695  QVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  775  ELGGEGD-IDNAPWPVADEQAMVENTTLVVVQVNGKVRGKITVAVDATEEQVRERAGQEH  833
             L + G+ I   PWP  DE  +VEN   +VVQ++GKV++K+ VA D + E+++E A  ++
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  834  LVAKYLDGVTVRKVIYVPGKLLNLVV  859
             V   + G  + KVI VP KL+N+V+
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVI  832

1359) W5S_3142 in NC_017845


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  531 bits (2003),  Expect = 9e-152, Method: Compositional matrix adjust.
 Identities = 353/876 (41%), Positives = 544/876 (63%), Gaps = 68/876 (7%)

Query  5    YRPEEIEADVQLHWQEKQTFKVTEQPGKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIS  63
            Y    IE+  Q  W +++TFK   +++K K+Y L M+PYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYANIDYMKNQLKLLGFGYDWDR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T  NI   K Q++ LGF+YDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVATCKPDYYRWEQWFFTKLYEKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            EV T  P+YY+W QW+FTKLYEKGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADQLLNDLDTLESWPEQVKTMQRNWIGRSEGVEITFDVADSTEK  242
            V RK + QW +KITAYA++LL+DL+ ++ WPE +K MQRNWIG+S G ++TF V D+   
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LSVYTTRPDTFMGVTYVavaaghplaaqaaatnpalaDFIAECRNTKVAEADMA----TM  298
            ++V+TTRPDT+ G TY     +   A   A T +  A+ +A+ +      +D+A    + 
Sbjct  243  FTVFTTRPDTLFGATYA--VLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  299  EKKGIATGLYAIHPLNGEKVAIWVANFVLMEYGTGAVMAVPGHDQRDWEFATKYDLSIKP  358
            EK G+ TG YAI+P+NG  +++W+A++VL  YGTGA+MAVP+HD+RDWEFA +++L I P
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VILNADGSKPDLSTEAMTEKGSLFNSGEFDGLDFDAAFNAIADKLVEKGIGERKVNYRLR  418
            V+  ++   + ++ +++  ++ +     +DGLD  +A+  + + L   G+G+ +V YRLR
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDF-----LDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  419  DWGVSRQRYWGAPIPMVTLEDGTVIPTPEDQLPVILP--EDVVMDGIT-SPLKSNPEWAK  475
            DW  SRQRYWG PIP++  EDGT  + PE +LP++LP   D+   G   SPL +  +W  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  476  TT-VNGQPALRETDTFDTFMESSWYYARYTCPQYDQGMLDPAAANYWLPVDQYVGGIEHA  534
             T  +G  + RET+T      SSWYY RY  P+  + + D    + WLPVD YVGG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  535  IMHLMYFRFFHKLMRDAGLVTSDEPAKRLLCQGMVLADAFYYLGNNGERIWVSPADVTVE  594
            ++HL+Y RF HK++ D G+V + EP ++L+ QGM+L+ ++                    
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY--------------------  575

Query  595  RDEKGRIVKAVDNEGRDVIY----------AGMSKMSKSKNNGIDPQVMVEKYGADTVRL  644
            RD +G +V +   E RD  +           + +KMSKS +N ++P+ +VE+YGADT+R+
Sbjct  576  RDSRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRV  635

Query  645  FMMFASPAEMTLEWQESGVEGANRFLKRVWRQAFEHTEKGATTALDVTTLTEDQKSLRRD  704
            + MF +P + ++ W E G+EG+ +FL RV R           T+ ++T   E+  +L + 
Sbjct  636  YEMFMGPLDASIAWSEEGLEGSRKFLDRVYRL---------ITTKEIT--EENSGALDKV  684

Query  705  LHKTIAKVTDDIGRRQTFNTAIAAIMELMNKLAKAPQESDQDRALTQETLLAVVRMLYPF  764
             + T+  VT+++++ + FNTAIA +M ++N        ++++  L  +   + V+++ PF
Sbjct  685  YNETVKAVTEQVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPF  736

Query  765  TPHVCFTLWQALQGEGD-VDTAPWPVADENAMVEDSKLVVVQVNGKVRGKITVAADASEE  823
            +PH+   LWQAL + G+ +   PWP  DE+ +VE+   +VVQ++GKV++K+ VA D S E
Sbjct  737  APHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSRE  796

Query  824  QVRERAAQEPLVAKYLDGVTVRKVIYVPGKLLNLVV  859
            +++E A  +  V   + G  + KVI VP KL+N+V+
Sbjct  797  ELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

1360) leuS in NC_021820


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  530 bits (2001),  Expect = 1e-151, Method: Compositional matrix adjust.
 Identities = 361/866 (42%), Positives = 552/866 (64%), Gaps = 48/866 (5%)

Query  5    YRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVVA  63
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKTLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q+++LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EIATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADELLRDLDKLDHWPDTVKTMQRNWIGRSEGVEITFDVKGYDNT  242
            V RK + QW +KITAYA+ LL DL+ +D WP+++K MQRNWIG+S G ++TF VK+ D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGATYLAVAAGHPlaqkaaannaelaaFIDECRNTKVAEAEMA----TM  298
            +TV+TTRPDT+ GATY  +A+ H+L +  ++++   A  + + +      +++A    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEA--VADYKRQASLKSDLARTDLAK  300

Query  299  EKKGVDTGYKAIHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLTIKP  358
            EK GV TG  AI+P+ G E+PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L I P
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VILAADGSEPDLSEQALTEKGVLFNSGEFDGLAFEAAFNAIADKLAEKGVGERKVNYRLR  418
            V+        ++ E A+TE G+ +NS+ +DGL   +A+  + + L   GVG+ +V YRLR
Sbjct  361  VL-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  419  DWGVSRQRYWGAPIPMVTLEDGTVLPTPEDQLPVILP--EDVVMDGIT-SPIKADPEWAK  475
            DW  SRQRYWG PIP++  EDGT  + PE +LP++LP   D+   G   SP+    +W  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  476  TT-VNGMPALRETDTFDTFMESSWYYARYTCPQYQEGMLDSKAANYWLPVDIYIGGIEHA  534
             T  +G+ + RET+T      SSWYY RY  P+  E + D    + WLPVDIY+GG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  535  IMHLLYFRFFHKLMRDAGMVTSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVE  594
            ++HLLY RF HK++ D G+V + EP ++L+ QGM+L+ ++      + R  + + D +  
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEK  590

Query  595  RDEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADM  654
            RD  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D 
Sbjct  591  RD--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  655  TLEWQESGVEGANRFIKRVWKLVYEHTAKGPVAALNVDALSEDQKALRRDVHKTIAKVTD  714
            ++ W E G+EG+ +F+ RV +L+   T+K        +   E+  AL +  + T+  VT+
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLI---TTK--------EITEENSGALDKVYNETVKAVTE  694

Query  715  DIGRRQTFNTAIAAIMELMNKLAKAPQEGEQDRALLQEALQAVVRMLNPFTPHVCFTLWQ  774
            ++++ + FNTAIA +M ++N        ++++  L+ +  ++ V+++ PF+PH+   LWQ
Sbjct  695  QVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  775  ELGGEGD-IDNAPWPVADEQAMVENTTLVVVQVNGKVRGKITVPVDATEEQVRERAGQEH  833
             L + G+ I   PWP  DE  +VEN   +VVQ++GKV++K+ V+ D + E+++E A  ++
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  834  LVAKYLDGVTVRKVIYVPGKLLNLVV  859
             V   + G  + KVI VP KL+N+V+
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVI  832

1361) leuS in NC_011205


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  530 bits (2001),  Expect = 1e-151, Method: Compositional matrix adjust.
 Identities = 361/866 (42%), Positives = 552/866 (64%), Gaps = 48/866 (5%)

Query  5    YRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVVA  63
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKTLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q+++LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EIATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADELLRDLDKLDHWPDTVKTMQRNWIGRSEGVEITFDVKGYDNT  242
            V RK + QW +KITAYA+ LL DL+ +D WP+++K MQRNWIG+S G ++TF VK+ D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGATYLAVAAGHPlaqkaaannaelaaFIDECRNTKVAEAEMA----TM  298
            +TV+TTRPDT+ GATY  +A+ H+L +  ++++   A  + + +      +++A    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEA--VADYKRQASLKSDLARTDLAK  300

Query  299  EKKGVDTGYKAIHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLTIKP  358
            EK GV TG  AI+P+ G E+PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L I P
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VILAADGSEPDLSEQALTEKGVLFNSGEFDGLAFEAAFNAIADKLAEKGVGERKVNYRLR  418
            V+        ++ E A+TE G+ +NS+ +DGL   +A+  + + L   GVG+ +V YRLR
Sbjct  361  VL-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  419  DWGVSRQRYWGAPIPMVTLEDGTVLPTPEDQLPVILP--EDVVMDGIT-SPIKADPEWAK  475
            DW  SRQRYWG PIP++  EDGT  + PE +LP++LP   D+   G   SP+    +W  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  476  TT-VNGMPALRETDTFDTFMESSWYYARYTCPQYQEGMLDSKAANYWLPVDIYIGGIEHA  534
             T  +G+ + RET+T      SSWYY RY  P+  E + D    + WLPVDIY+GG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  535  IMHLLYFRFFHKLMRDAGMVTSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVE  594
            ++HLLY RF HK++ D G+V + EP ++L+ QGM+L+ ++      + R  + + D +  
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEK  590

Query  595  RDEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADM  654
            RD  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D 
Sbjct  591  RD--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  655  TLEWQESGVEGANRFIKRVWKLVYEHTAKGPVAALNVDALSEDQKALRRDVHKTIAKVTD  714
            ++ W E G+EG+ +F+ RV +L+   T+K        +   E+  AL +  + T+  VT+
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLI---TTK--------EITEENSGALDKVYNETVKAVTE  694

Query  715  DIGRRQTFNTAIAAIMELMNKLAKAPQEGEQDRALLQEALQAVVRMLNPFTPHVCFTLWQ  774
            ++++ + FNTAIA +M ++N        ++++  L+ +  ++ V+++ PF+PH+   LWQ
Sbjct  695  QVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  775  ELGGEGD-IDNAPWPVADEQAMVENTTLVVVQVNGKVRGKITVPVDATEEQVRERAGQEH  833
             L + G+ I   PWP  DE  +VEN   +VVQ++GKV++K+ V+ D + E+++E A  ++
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  834  LVAKYLDGVTVRKVIYVPGKLLNLVV  859
             V   + G  + KVI VP KL+N+V+
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVI  832

1362) STM14_0756 in NC_016856


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  530 bits (2001),  Expect = 1e-151, Method: Compositional matrix adjust.
 Identities = 361/866 (42%), Positives = 552/866 (64%), Gaps = 48/866 (5%)

Query  5    YRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVVA  63
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKTLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q+++LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EIATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADELLRDLDKLDHWPDTVKTMQRNWIGRSEGVEITFDVKGYDNT  242
            V RK + QW +KITAYA+ LL DL+ +D WP+++K MQRNWIG+S G ++TF VK+ D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGATYLAVAAGHPlaqkaaannaelaaFIDECRNTKVAEAEMA----TM  298
            +TV+TTRPDT+ GATY  +A+ H+L +  ++++   A  + + +      +++A    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEA--VADYKRQASLKSDLARTDLAK  300

Query  299  EKKGVDTGYKAIHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLTIKP  358
            EK GV TG  AI+P+ G E+PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L I P
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VILAADGSEPDLSEQALTEKGVLFNSGEFDGLAFEAAFNAIADKLAEKGVGERKVNYRLR  418
            V+        ++ E A+TE G+ +NS+ +DGL   +A+  + + L   GVG+ +V YRLR
Sbjct  361  VL-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  419  DWGVSRQRYWGAPIPMVTLEDGTVLPTPEDQLPVILP--EDVVMDGIT-SPIKADPEWAK  475
            DW  SRQRYWG PIP++  EDGT  + PE +LP++LP   D+   G   SP+    +W  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  476  TT-VNGMPALRETDTFDTFMESSWYYARYTCPQYQEGMLDSKAANYWLPVDIYIGGIEHA  534
             T  +G+ + RET+T      SSWYY RY  P+  E + D    + WLPVDIY+GG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  535  IMHLLYFRFFHKLMRDAGMVTSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVE  594
            ++HLLY RF HK++ D G+V + EP ++L+ QGM+L+ ++      + R  + + D +  
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEK  590

Query  595  RDEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADM  654
            RD  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D 
Sbjct  591  RD--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  655  TLEWQESGVEGANRFIKRVWKLVYEHTAKGPVAALNVDALSEDQKALRRDVHKTIAKVTD  714
            ++ W E G+EG+ +F+ RV +L+   T+K        +   E+  AL +  + T+  VT+
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLI---TTK--------EITEENSGALDKVYNETVKAVTE  694

Query  715  DIGRRQTFNTAIAAIMELMNKLAKAPQEGEQDRALLQEALQAVVRMLNPFTPHVCFTLWQ  774
            ++++ + FNTAIA +M ++N        ++++  L+ +  ++ V+++ PF+PH+   LWQ
Sbjct  695  QVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  775  ELGGEGD-IDNAPWPVADEQAMVENTTLVVVQVNGKVRGKITVPVDATEEQVRERAGQEH  833
             L + G+ I   PWP  DE  +VEN   +VVQ++GKV++K+ V+ D + E+++E A  ++
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  834  LVAKYLDGVTVRKVIYVPGKLLNLVV  859
             V   + G  + KVI VP KL+N+V+
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVI  832

1363) STMMW_07131 in NC_016854


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  530 bits (2001),  Expect = 1e-151, Method: Compositional matrix adjust.
 Identities = 361/866 (42%), Positives = 552/866 (64%), Gaps = 48/866 (5%)

Query  5    YRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVVA  63
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKTLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q+++LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EIATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADELLRDLDKLDHWPDTVKTMQRNWIGRSEGVEITFDVKGYDNT  242
            V RK + QW +KITAYA+ LL DL+ +D WP+++K MQRNWIG+S G ++TF VK+ D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGATYLAVAAGHPlaqkaaannaelaaFIDECRNTKVAEAEMA----TM  298
            +TV+TTRPDT+ GATY  +A+ H+L +  ++++   A  + + +      +++A    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEA--VADYKRQASLKSDLARTDLAK  300

Query  299  EKKGVDTGYKAIHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLTIKP  358
            EK GV TG  AI+P+ G E+PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L I P
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VILAADGSEPDLSEQALTEKGVLFNSGEFDGLAFEAAFNAIADKLAEKGVGERKVNYRLR  418
            V+        ++ E A+TE G+ +NS+ +DGL   +A+  + + L   GVG+ +V YRLR
Sbjct  361  VL-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  419  DWGVSRQRYWGAPIPMVTLEDGTVLPTPEDQLPVILP--EDVVMDGIT-SPIKADPEWAK  475
            DW  SRQRYWG PIP++  EDGT  + PE +LP++LP   D+   G   SP+    +W  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  476  TT-VNGMPALRETDTFDTFMESSWYYARYTCPQYQEGMLDSKAANYWLPVDIYIGGIEHA  534
             T  +G+ + RET+T      SSWYY RY  P+  E + D    + WLPVDIY+GG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  535  IMHLLYFRFFHKLMRDAGMVTSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVE  594
            ++HLLY RF HK++ D G+V + EP ++L+ QGM+L+ ++      + R  + + D +  
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEK  590

Query  595  RDEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADM  654
            RD  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D 
Sbjct  591  RD--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  655  TLEWQESGVEGANRFIKRVWKLVYEHTAKGPVAALNVDALSEDQKALRRDVHKTIAKVTD  714
            ++ W E G+EG+ +F+ RV +L+   T+K        +   E+  AL +  + T+  VT+
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLI---TTK--------EITEENSGALDKVYNETVKAVTE  694

Query  715  DIGRRQTFNTAIAAIMELMNKLAKAPQEGEQDRALLQEALQAVVRMLNPFTPHVCFTLWQ  774
            ++++ + FNTAIA +M ++N        ++++  L+ +  ++ V+++ PF+PH+   LWQ
Sbjct  695  QVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  775  ELGGEGD-IDNAPWPVADEQAMVENTTLVVVQVNGKVRGKITVPVDATEEQVRERAGQEH  833
             L + G+ I   PWP  DE  +VEN   +VVQ++GKV++K+ V+ D + E+++E A  ++
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  834  LVAKYLDGVTVRKVIYVPGKLLNLVV  859
             V   + G  + KVI VP KL+N+V+
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVI  832

1364) leuS in NC_003197


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  530 bits (2001),  Expect = 1e-151, Method: Compositional matrix adjust.
 Identities = 361/866 (42%), Positives = 552/866 (64%), Gaps = 48/866 (5%)

Query  5    YRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVVA  63
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKTLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q+++LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EIATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADELLRDLDKLDHWPDTVKTMQRNWIGRSEGVEITFDVKGYDNT  242
            V RK + QW +KITAYA+ LL DL+ +D WP+++K MQRNWIG+S G ++TF VK+ D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGATYLAVAAGHPlaqkaaannaelaaFIDECRNTKVAEAEMA----TM  298
            +TV+TTRPDT+ GATY  +A+ H+L +  ++++   A  + + +      +++A    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEA--VADYKRQASLKSDLARTDLAK  300

Query  299  EKKGVDTGYKAIHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLTIKP  358
            EK GV TG  AI+P+ G E+PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L I P
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VILAADGSEPDLSEQALTEKGVLFNSGEFDGLAFEAAFNAIADKLAEKGVGERKVNYRLR  418
            V+        ++ E A+TE G+ +NS+ +DGL   +A+  + + L   GVG+ +V YRLR
Sbjct  361  VL-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  419  DWGVSRQRYWGAPIPMVTLEDGTVLPTPEDQLPVILP--EDVVMDGIT-SPIKADPEWAK  475
            DW  SRQRYWG PIP++  EDGT  + PE +LP++LP   D+   G   SP+    +W  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  476  TT-VNGMPALRETDTFDTFMESSWYYARYTCPQYQEGMLDSKAANYWLPVDIYIGGIEHA  534
             T  +G+ + RET+T      SSWYY RY  P+  E + D    + WLPVDIY+GG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  535  IMHLLYFRFFHKLMRDAGMVTSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVE  594
            ++HLLY RF HK++ D G+V + EP ++L+ QGM+L+ ++      + R  + + D +  
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEK  590

Query  595  RDEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADM  654
            RD  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D 
Sbjct  591  RD--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  655  TLEWQESGVEGANRFIKRVWKLVYEHTAKGPVAALNVDALSEDQKALRRDVHKTIAKVTD  714
            ++ W E G+EG+ +F+ RV +L+   T+K        +   E+  AL +  + T+  VT+
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLI---TTK--------EITEENSGALDKVYNETVKAVTE  694

Query  715  DIGRRQTFNTAIAAIMELMNKLAKAPQEGEQDRALLQEALQAVVRMLNPFTPHVCFTLWQ  774
            ++++ + FNTAIA +M ++N        ++++  L+ +  ++ V+++ PF+PH+   LWQ
Sbjct  695  QVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  775  ELGGEGD-IDNAPWPVADEQAMVENTTLVVVQVNGKVRGKITVPVDATEEQVRERAGQEH  833
             L + G+ I   PWP  DE  +VEN   +VVQ++GKV++K+ V+ D + E+++E A  ++
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  834  LVAKYLDGVTVRKVIYVPGKLLNLVV  859
             V   + G  + KVI VP KL+N+V+
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVI  832

1365) leuS in NC_016810


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  530 bits (2001),  Expect = 1e-151, Method: Compositional matrix adjust.
 Identities = 361/866 (42%), Positives = 552/866 (64%), Gaps = 48/866 (5%)

Query  5    YRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVVA  63
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKTLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q+++LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EIATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADELLRDLDKLDHWPDTVKTMQRNWIGRSEGVEITFDVKGYDNT  242
            V RK + QW +KITAYA+ LL DL+ +D WP+++K MQRNWIG+S G ++TF VK+ D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGATYLAVAAGHPlaqkaaannaelaaFIDECRNTKVAEAEMA----TM  298
            +TV+TTRPDT+ GATY  +A+ H+L +  ++++   A  + + +      +++A    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEA--VADYKRQASLKSDLARTDLAK  300

Query  299  EKKGVDTGYKAIHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLTIKP  358
            EK GV TG  AI+P+ G E+PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L I P
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VILAADGSEPDLSEQALTEKGVLFNSGEFDGLAFEAAFNAIADKLAEKGVGERKVNYRLR  418
            V+        ++ E A+TE G+ +NS+ +DGL   +A+  + + L   GVG+ +V YRLR
Sbjct  361  VL-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  419  DWGVSRQRYWGAPIPMVTLEDGTVLPTPEDQLPVILP--EDVVMDGIT-SPIKADPEWAK  475
            DW  SRQRYWG PIP++  EDGT  + PE +LP++LP   D+   G   SP+    +W  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  476  TT-VNGMPALRETDTFDTFMESSWYYARYTCPQYQEGMLDSKAANYWLPVDIYIGGIEHA  534
             T  +G+ + RET+T      SSWYY RY  P+  E + D    + WLPVDIY+GG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  535  IMHLLYFRFFHKLMRDAGMVTSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVE  594
            ++HLLY RF HK++ D G+V + EP ++L+ QGM+L+ ++      + R  + + D +  
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEK  590

Query  595  RDEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADM  654
            RD  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D 
Sbjct  591  RD--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  655  TLEWQESGVEGANRFIKRVWKLVYEHTAKGPVAALNVDALSEDQKALRRDVHKTIAKVTD  714
            ++ W E G+EG+ +F+ RV +L+   T+K        +   E+  AL +  + T+  VT+
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLI---TTK--------EITEENSGALDKVYNETVKAVTE  694

Query  715  DIGRRQTFNTAIAAIMELMNKLAKAPQEGEQDRALLQEALQAVVRMLNPFTPHVCFTLWQ  774
            ++++ + FNTAIA +M ++N        ++++  L+ +  ++ V+++ PF+PH+   LWQ
Sbjct  695  QVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  775  ELGGEGD-IDNAPWPVADEQAMVENTTLVVVQVNGKVRGKITVPVDATEEQVRERAGQEH  833
             L + G+ I   PWP  DE  +VEN   +VVQ++GKV++K+ V+ D + E+++E A  ++
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  834  LVAKYLDGVTVRKVIYVPGKLLNLVV  859
             V   + G  + KVI VP KL+N+V+
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVI  832

1366) leuS in NC_016860


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  530 bits (2001),  Expect = 1e-151, Method: Compositional matrix adjust.
 Identities = 361/866 (42%), Positives = 552/866 (64%), Gaps = 48/866 (5%)

Query  5    YRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVVA  63
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKTLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q+++LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EIATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADELLRDLDKLDHWPDTVKTMQRNWIGRSEGVEITFDVKGYDNT  242
            V RK + QW +KITAYA+ LL DL+ +D WP+++K MQRNWIG+S G ++TF VK+ D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGATYLAVAAGHPlaqkaaannaelaaFIDECRNTKVAEAEMA----TM  298
            +TV+TTRPDT+ GATY  +A+ H+L +  ++++   A  + + +      +++A    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEA--VADYKRQASLKSDLARTDLAK  300

Query  299  EKKGVDTGYKAIHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLTIKP  358
            EK GV TG  AI+P+ G E+PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L I P
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VILAADGSEPDLSEQALTEKGVLFNSGEFDGLAFEAAFNAIADKLAEKGVGERKVNYRLR  418
            V+        ++ E A+TE G+ +NS+ +DGL   +A+  + + L   GVG+ +V YRLR
Sbjct  361  VL-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  419  DWGVSRQRYWGAPIPMVTLEDGTVLPTPEDQLPVILP--EDVVMDGIT-SPIKADPEWAK  475
            DW  SRQRYWG PIP++  EDGT  + PE +LP++LP   D+   G   SP+    +W  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  476  TT-VNGMPALRETDTFDTFMESSWYYARYTCPQYQEGMLDSKAANYWLPVDIYIGGIEHA  534
             T  +G+ + RET+T      SSWYY RY  P+  E + D    + WLPVDIY+GG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  535  IMHLLYFRFFHKLMRDAGMVTSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVE  594
            ++HLLY RF HK++ D G+V + EP ++L+ QGM+L+ ++      + R  + + D +  
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEK  590

Query  595  RDEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADM  654
            RD  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D 
Sbjct  591  RD--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  655  TLEWQESGVEGANRFIKRVWKLVYEHTAKGPVAALNVDALSEDQKALRRDVHKTIAKVTD  714
            ++ W E G+EG+ +F+ RV +L+   T+K        +   E+  AL +  + T+  VT+
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLI---TTK--------EITEENSGALDKVYNETVKAVTE  694

Query  715  DIGRRQTFNTAIAAIMELMNKLAKAPQEGEQDRALLQEALQAVVRMLNPFTPHVCFTLWQ  774
            ++++ + FNTAIA +M ++N        ++++  L+ +  ++ V+++ PF+PH+   LWQ
Sbjct  695  QVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  775  ELGGEGD-IDNAPWPVADEQAMVENTTLVVVQVNGKVRGKITVPVDATEEQVRERAGQEH  833
             L + G+ I   PWP  DE  +VEN   +VVQ++GKV++K+ V+ D + E+++E A  ++
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  834  LVAKYLDGVTVRKVIYVPGKLLNLVV  859
             V   + G  + KVI VP KL+N+V+
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVI  832

1367) leuS in NC_021151


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  530 bits (2001),  Expect = 1e-151, Method: Compositional matrix adjust.
 Identities = 361/866 (42%), Positives = 552/866 (64%), Gaps = 48/866 (5%)

Query  5    YRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVVA  63
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKTLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q+++LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EIATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADELLRDLDKLDHWPDTVKTMQRNWIGRSEGVEITFDVKGYDNT  242
            V RK + QW +KITAYA+ LL DL+ +D WP+++K MQRNWIG+S G ++TF VK+ D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGATYLAVAAGHPlaqkaaannaelaaFIDECRNTKVAEAEMA----TM  298
            +TV+TTRPDT+ GATY  +A+ H+L +  ++++   A  + + +      +++A    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEA--VADYKRQASLKSDLARTDLAK  300

Query  299  EKKGVDTGYKAIHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLTIKP  358
            EK GV TG  AI+P+ G E+PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L I P
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VILAADGSEPDLSEQALTEKGVLFNSGEFDGLAFEAAFNAIADKLAEKGVGERKVNYRLR  418
            V+        ++ E A+TE G+ +NS+ +DGL   +A+  + + L   GVG+ +V YRLR
Sbjct  361  VL-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  419  DWGVSRQRYWGAPIPMVTLEDGTVLPTPEDQLPVILP--EDVVMDGIT-SPIKADPEWAK  475
            DW  SRQRYWG PIP++  EDGT  + PE +LP++LP   D+   G   SP+    +W  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  476  TT-VNGMPALRETDTFDTFMESSWYYARYTCPQYQEGMLDSKAANYWLPVDIYIGGIEHA  534
             T  +G+ + RET+T      SSWYY RY  P+  E + D    + WLPVDIY+GG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  535  IMHLLYFRFFHKLMRDAGMVTSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVE  594
            ++HLLY RF HK++ D G+V + EP ++L+ QGM+L+ ++      + R  + + D +  
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEK  590

Query  595  RDEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADM  654
            RD  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D 
Sbjct  591  RD--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  655  TLEWQESGVEGANRFIKRVWKLVYEHTAKGPVAALNVDALSEDQKALRRDVHKTIAKVTD  714
            ++ W E G+EG+ +F+ RV +L+   T+K        +   E+  AL +  + T+  VT+
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLI---TTK--------EITEENSGALDKVYNETVKAVTE  694

Query  715  DIGRRQTFNTAIAAIMELMNKLAKAPQEGEQDRALLQEALQAVVRMLNPFTPHVCFTLWQ  774
            ++++ + FNTAIA +M ++N        ++++  L+ +  ++ V+++ PF+PH+   LWQ
Sbjct  695  QVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  775  ELGGEGD-IDNAPWPVADEQAMVENTTLVVVQVNGKVRGKITVPVDATEEQVRERAGQEH  833
             L + G+ I   PWP  DE  +VEN   +VVQ++GKV++K+ V+ D + E+++E A  ++
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  834  LVAKYLDGVTVRKVIYVPGKLLNLVV  859
             V   + G  + KVI VP KL+N+V+
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVI  832

1368) leuS in NC_016863


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  530 bits (2001),  Expect = 1e-151, Method: Compositional matrix adjust.
 Identities = 361/866 (42%), Positives = 552/866 (64%), Gaps = 48/866 (5%)

Query  5    YRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVVA  63
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKTLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q+++LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EIATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADELLRDLDKLDHWPDTVKTMQRNWIGRSEGVEITFDVKGYDNT  242
            V RK + QW +KITAYA+ LL DL+ +D WP+++K MQRNWIG+S G ++TF VK+ D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGATYLAVAAGHPlaqkaaannaelaaFIDECRNTKVAEAEMA----TM  298
            +TV+TTRPDT+ GATY  +A+ H+L +  ++++   A  + + +      +++A    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEA--VADYKRQASLKSDLARTDLAK  300

Query  299  EKKGVDTGYKAIHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLTIKP  358
            EK GV TG  AI+P+ G E+PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L I P
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VILAADGSEPDLSEQALTEKGVLFNSGEFDGLAFEAAFNAIADKLAEKGVGERKVNYRLR  418
            V+        ++ E A+TE G+ +NS+ +DGL   +A+  + + L   GVG+ +V YRLR
Sbjct  361  VL-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  419  DWGVSRQRYWGAPIPMVTLEDGTVLPTPEDQLPVILP--EDVVMDGIT-SPIKADPEWAK  475
            DW  SRQRYWG PIP++  EDGT  + PE +LP++LP   D+   G   SP+    +W  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  476  TT-VNGMPALRETDTFDTFMESSWYYARYTCPQYQEGMLDSKAANYWLPVDIYIGGIEHA  534
             T  +G+ + RET+T      SSWYY RY  P+  E + D    + WLPVDIY+GG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  535  IMHLLYFRFFHKLMRDAGMVTSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVE  594
            ++HLLY RF HK++ D G+V + EP ++L+ QGM+L+ ++      + R  + + D +  
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEK  590

Query  595  RDEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADM  654
            RD  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D 
Sbjct  591  RD--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  655  TLEWQESGVEGANRFIKRVWKLVYEHTAKGPVAALNVDALSEDQKALRRDVHKTIAKVTD  714
            ++ W E G+EG+ +F+ RV +L+   T+K        +   E+  AL +  + T+  VT+
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLI---TTK--------EITEENSGALDKVYNETVKAVTE  694

Query  715  DIGRRQTFNTAIAAIMELMNKLAKAPQEGEQDRALLQEALQAVVRMLNPFTPHVCFTLWQ  774
            ++++ + FNTAIA +M ++N        ++++  L+ +  ++ V+++ PF+PH+   LWQ
Sbjct  695  QVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  775  ELGGEGD-IDNAPWPVADEQAMVENTTLVVVQVNGKVRGKITVPVDATEEQVRERAGQEH  833
             L + G+ I   PWP  DE  +VEN   +VVQ++GKV++K+ V+ D + E+++E A  ++
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  834  LVAKYLDGVTVRKVIYVPGKLLNLVV  859
             V   + G  + KVI VP KL+N+V+
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVI  832

1369) leuS in NC_021814


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  530 bits (2001),  Expect = 1e-151, Method: Compositional matrix adjust.
 Identities = 361/866 (42%), Positives = 552/866 (64%), Gaps = 48/866 (5%)

Query  5    YRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVVA  63
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKTLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q+++LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EIATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADELLRDLDKLDHWPDTVKTMQRNWIGRSEGVEITFDVKGYDNT  242
            V RK + QW +KITAYA+ LL DL+ +D WP+++K MQRNWIG+S G ++TF VK+ D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGATYLAVAAGHPlaqkaaannaelaaFIDECRNTKVAEAEMA----TM  298
            +TV+TTRPDT+ GATY  +A+ H+L +  ++++   A  + + +      +++A    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEA--VADYKRQASLKSDLARTDLAK  300

Query  299  EKKGVDTGYKAIHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLTIKP  358
            EK GV TG  AI+P+ G E+PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L I P
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VILAADGSEPDLSEQALTEKGVLFNSGEFDGLAFEAAFNAIADKLAEKGVGERKVNYRLR  418
            V+        ++ E A+TE G+ +NS+ +DGL   +A+  + + L   GVG+ +V YRLR
Sbjct  361  VL-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  419  DWGVSRQRYWGAPIPMVTLEDGTVLPTPEDQLPVILP--EDVVMDGIT-SPIKADPEWAK  475
            DW  SRQRYWG PIP++  EDGT  + PE +LP++LP   D+   G   SP+    +W  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  476  TT-VNGMPALRETDTFDTFMESSWYYARYTCPQYQEGMLDSKAANYWLPVDIYIGGIEHA  534
             T  +G+ + RET+T      SSWYY RY  P+  E + D    + WLPVDIY+GG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  535  IMHLLYFRFFHKLMRDAGMVTSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVE  594
            ++HLLY RF HK++ D G+V + EP ++L+ QGM+L+ ++      + R  + + D +  
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEK  590

Query  595  RDEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADM  654
            RD  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D 
Sbjct  591  RD--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  655  TLEWQESGVEGANRFIKRVWKLVYEHTAKGPVAALNVDALSEDQKALRRDVHKTIAKVTD  714
            ++ W E G+EG+ +F+ RV +L+   T+K        +   E+  AL +  + T+  VT+
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLI---TTK--------EITEENSGALDKVYNETVKAVTE  694

Query  715  DIGRRQTFNTAIAAIMELMNKLAKAPQEGEQDRALLQEALQAVVRMLNPFTPHVCFTLWQ  774
            ++++ + FNTAIA +M ++N        ++++  L+ +  ++ V+++ PF+PH+   LWQ
Sbjct  695  QVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  775  ELGGEGD-IDNAPWPVADEQAMVENTTLVVVQVNGKVRGKITVPVDATEEQVRERAGQEH  833
             L + G+ I   PWP  DE  +VEN   +VVQ++GKV++K+ V+ D + E+++E A  ++
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  834  LVAKYLDGVTVRKVIYVPGKLLNLVV  859
             V   + G  + KVI VP KL+N+V+
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVI  832

1370) PC1_1187 in NC_012917


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  530 bits (2001),  Expect = 1e-151, Method: Compositional matrix adjust.
 Identities = 357/875 (41%), Positives = 550/875 (63%), Gaps = 66/875 (7%)

Query  5    YRPEEIEADVQLHWQEKQTFKVTEQPGKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIS  63
            Y    IE+  Q  W +++TFK   +++K K+Y L M+PYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYANIDYMKNQLKLLGFGYDWDR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T  NI   K Q++ LGF+YDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVATCKPDYYRWEQWFFTKLYEKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            EV T  P+YY+W QW+FTKLYEKGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADQLLNDLDTLESWPEQVKTMQRNWIGRSEGVEITFDVADSAEK  242
            V RK + QW +KITAYA++LL+DL+ ++ WPE +K MQRNWIG+S G ++TF V D+   
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGVTYVavaaghplaaqaaaanpaladfi---aECRNTKVAEADMATME  299
            +TV+TTRPDT+ G TY  +A+ H+L    ++++ A A          ++ +A +D+A  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGMATGLYAIHPLNGEKVAIWVANFVLMEYGTGAVMAVPGHDQRDWEFATKYDLSIKPV  359
            K G+ TG YAI+P+NG  +++W+A++VL  YGTGA+MAVP+HD+RDWEFA +++L I PV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  360  ILNADGSEPDLSAEAMTEKGNLFNSGEFDGLDFDAAFNAIADKLVEKGIGERKVNYRLRD  419
            +  ++  E+ ++ +++  ++++     +DGLD  +A+  + + L   G+G+ +V YRLRD
Sbjct  362  LEGGNVEEAAFTEDGLHINSDF-----LDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMVTLEDGTVIPTPEDQLPVILP--EDVVMDGIT-SPLKSNPEWAKT  476
            W  SRQRYWG PIP++  EDGT  + PE +LP++LP   D+   G   SPL +  +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  T-VNGQPALRETDTFDTFMESSWYYARYTCPQYDQGMLDPAAANYWLPVDQYVGGIEHAI  535
            T  +G  + RET+T      SSWYY RY  P+  + + D    + WLPVD YVGG EHA+
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLMYFRFFHKLMRDAGLVTSDEPAKRLLCQGMVLADAFYYLGNNGERVWVSPIDVDVER  595
            +HL+Y RF HK++ D G+V + EP ++L+ QGM+L+ ++                    R
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY--------------------R  576

Query  596  DEKGRIVKAVDNEGRDVIY----------AGMSKMSKSKNNGIDPQVMVEKYGADTVRLF  645
            D +G +V +   E RD  +           + +KMSKS +N ++P+ +VE+YGADT+R++
Sbjct  577  DSRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVY  636

Query  646  MMFASPAEMTLEWQESGVEGANRFLKRVWRQAFEHTEKGATTALDVATLTEDQKSLRRDL  705
             MF +P + ++ W E G+EG+ +FL RV R           T+ +++   E+  +L +  
Sbjct  637  EMFMGPLDASIAWSEEGLEGSRKFLDRVYRL---------ITTKEIT--EENSGALDKVY  685

Query  706  HKTIAKVTDDIGRRQTFNTAIAAIMELMNKLAKAPQDSDQDRALTQETLLAVVRMLYPFT  765
            + T+  VT+++++ + FNTAIA +M ++N        ++++  L  +   + V+++ PF+
Sbjct  686  NETVKAVTEQVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFA  737

Query  766  PHVCFTLWQALQGEGD-IDTAPWPVADESAMVEDSKLVVVQVNGKVRGKITVAADASEEQ  824
            PH+   LWQAL + G+ I   PWP  DES +VE+   +VVQ++GKV++K+ VA D S E+
Sbjct  738  PHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREE  797

Query  825  VRERAAQEPLVAKYLDGVTVRKVIYVPGKLLNLVV  859
            ++E A  +  V   + G  + KVI VP KL+N+V+
Sbjct  798  LQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

1371) leuS in NC_018289


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  530 bits (2000),  Expect = 2e-151, Method: Compositional matrix adjust.
 Identities = 356/733 (49%), Positives = 502/733 (69%), Gaps = 52/733 (7%)

Query  225  LVYRADSMVNWCPGLGTVLANEEVTSEGRSDRGNFPVFRKRLRQWMMRITAYSDRLLEDL  284
            L Y A+  VNW   LGT +ANEEV ++G S+RG +PV RK +RQWM++ITAY++RLLEDL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  285  DVLDWPEKVKTMQRNWIGRSTGASVLFAT--AADDIEVFTTRPDTLFGATYLVLAPEHDL  342
            + +DWPE +K MQRNWIG+STGA+V F    +  D+ VFTTRPDTLFGATY VLAPEH L
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  343  VDTLVTDAWPDGTDERWTYGAATPREAVAAYRTDIAAKSDLERQE-NKTKTGVFLGAYAT  401
            VD++ T               +   EAVA Y+ + + KSDL R +  K KTGV  G+YA 
Sbjct  268  VDAITT---------------SDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAI  312

Query  402  NPADGKQVPIFIADYVLAGYGTGAIMAVPGGDQRDWDFAKEFGLPIIEVVTGGDISEAAY  461
            NP +GK++P+ IADYVLA+YGTGAIMAVP+ D+RDW+FAK+F L II V+ GG++ EAA+
Sbjct  313  NPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEAAF  372

Query  462  AGDGTMVNSGFLDGMDVASAKEAIIARLEADGRGKRRVEYKLRDWLFARQRYWGEPFPIV  521
            + DG  +NS+FLDG+D ASA   ++ +LEA+G G+  V Y+LRDWLF+RQRYWGEP+PI+
Sbjct  373  TEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPII  432

Query  522  YDADGRAHPLPESALPVELPDVPDYSPVLFdpddadsepsppLNKATEWVHVELDLGDGL  581
               DG + ++PES LP+ LP   D  P         +   +PL + T+W++V  +  DG+
Sbjct  433  HWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTDWLEVTRE--DGV  482

Query  582  QSYTRDTNVMPQWAGSSWYELRYTDPHNPDEMCAKENEAYWMGPRPDEHGPEDPGGVDLY  641
            ++  R+TN MPQWAGSSWY LRY DPHN + +   E    W+              VD+Y
Sbjct  483  KG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWL-------------PVDIY  528

Query  642  VGGVEHAVLHLLYSRFWHKVLYDLGYVSSREPYRRLVNQGYIQAFAYTDSRGTYVPAAEV  701
            VGG EHAVLHLLY+RFWHKVLYDLG V+++EP+++L NQG I + +Y DSRG+ V++  V
Sbjct  529  VGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKV  588

Query  702  IERDGKFFWPGPDGEIEVNQEFGKIGKSLKNSVSPDEICDNYGADTLRVYEMSMGPLEAS  761
              RDG FF    +   E++Q  +K++KSLKN V+PD++ ++YGADTLRVYEM MGPL+AS
Sbjct  589  EKRDGSFF--HVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  762  RPWATKDVVGAHRFLQRVWRVVIDETSGNVRVVEHEALSDETLRLLHRTIEGVREDYAAL  821
             +W+  ++ G+++FL+RV R++   T+ ++   +  AL     ++ + T+ +V E+   +
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLI---TTKEITEENSGALD----KVYNETVKAVTEQVDQM  699

Query  822  RNNTAAAKLIEYTNHLTKEGVAARAAIEPLVLMVAPLAPHLAEELWKRL-GHDTSLAHGP  880
            + NTA A+L+ + N   KE+         +V ++AP+APHL+EELW+ L + + S++  P
Sbjct  700  KFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVP  759

Query  881  FPEADPQYLVEDTIEFPVQVNGKVRGKIVVaadadkaaleaaaladekVQAFLAGATPKK  940
             P  D   LVE+ +E+ VQ++GKV++K+VVA D  +  L+  ALA+EKVQA +AG    K
Sbjct  760  WPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIK  819

Query  941  VIVVPGRLVNLVV  953
            VI VP +LVN+V+
Sbjct  820  VIAVPNKLVNIVI  832


 Score =  131 bits (481),  Expect = 2e-31, Method: Compositional matrix adjust.
 Identities = 77/148 (53%), Positives = 100/148 (68%), Gaps = 11/148 (7%)

Query  28   IERAWQETWSDRGTFNVANPVGSLAPTDGSDVPADKMFVQDMFPYPSGDGLHVGHPLGYI  87
            IE  WQ  W+D  TF+            G+D +  K +  DMFPYPSG GLHVGHP GY 
Sbjct  9    IEPKWQAFWADNHTFKT-----------GTDASKPKFYALDMFPYPSGAGLHVGHPEGYT  57

Query  88   ATDVYARYYRMLGRNVLHALGFDAFGLPAEQYAVQTGTHPRTRTEANIVNFRRQLGRLGL  147
            ATD+ +R+ R  G+NVLH++G DAFGLPAEQYA++TG +P   T  NI NF+RQ+  LG+
Sbjct  58   ATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGF  117

Query  148  GHDTRRSFSTTDVDYYKWTQWIFLQIYN  175
            + D  R  +TTD +YYKWTQWIF ++Y+
Sbjct  118  SYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1372) leuS in NC_008596


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  530 bits (2000),  Expect = 2e-151, Method: Compositional matrix adjust.
 Identities = 356/733 (49%), Positives = 502/733 (69%), Gaps = 52/733 (7%)

Query  225  LVYRADSMVNWCPGLGTVLANEEVTSEGRSDRGNFPVFRKRLRQWMMRITAYSDRLLEDL  284
            L Y A+  VNW   LGT +ANEEV ++G S+RG +PV RK +RQWM++ITAY++RLLEDL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  285  DVLDWPEKVKTMQRNWIGRSTGASVLFAT--AADDIEVFTTRPDTLFGATYLVLAPEHDL  342
            + +DWPE +K MQRNWIG+STGA+V F    +  D+ VFTTRPDTLFGATY VLAPEH L
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  343  VDTLVTDAWPDGTDERWTYGAATPREAVAAYRTDIAAKSDLERQE-NKTKTGVFLGAYAT  401
            VD++ T               +   EAVA Y+ + + KSDL R +  K KTGV  G+YA 
Sbjct  268  VDAITT---------------SDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAI  312

Query  402  NPADGKQVPIFIADYVLAGYGTGAIMAVPGGDQRDWDFAKEFGLPIIEVVTGGDISEAAY  461
            NP +GK++P+ IADYVLA+YGTGAIMAVP+ D+RDW+FAK+F L II V+ GG++ EAA+
Sbjct  313  NPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEAAF  372

Query  462  AGDGTMVNSGFLDGMDVASAKEAIIARLEADGRGKRRVEYKLRDWLFARQRYWGEPFPIV  521
            + DG  +NS+FLDG+D ASA   ++ +LEA+G G+  V Y+LRDWLF+RQRYWGEP+PI+
Sbjct  373  TEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPII  432

Query  522  YDADGRAHPLPESALPVELPDVPDYSPVLFdpddadsepsppLNKATEWVHVELDLGDGL  581
               DG + ++PES LP+ LP   D  P         +   +PL + T+W++V  +  DG+
Sbjct  433  HWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTDWLEVTRE--DGV  482

Query  582  QSYTRDTNVMPQWAGSSWYELRYTDPHNPDEMCAKENEAYWMGPRPDEHGPEDPGGVDLY  641
            ++  R+TN MPQWAGSSWY LRY DPHN + +   E    W+              VD+Y
Sbjct  483  KG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWL-------------PVDIY  528

Query  642  VGGVEHAVLHLLYSRFWHKVLYDLGYVSSREPYRRLVNQGYIQAFAYTDSRGTYVPAAEV  701
            VGG EHAVLHLLY+RFWHKVLYDLG V+++EP+++L NQG I + +Y DSRG+ V++  V
Sbjct  529  VGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKV  588

Query  702  IERDGKFFWPGPDGEIEVNQEFGKIGKSLKNSVSPDEICDNYGADTLRVYEMSMGPLEAS  761
              RDG FF    +   E++Q  +K++KSLKN V+PD++ ++YGADTLRVYEM MGPL+AS
Sbjct  589  EKRDGSFF--HVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  762  RPWATKDVVGAHRFLQRVWRVVIDETSGNVRVVEHEALSDETLRLLHRTIEGVREDYAAL  821
             +W+  ++ G+++FL+RV R++   T+ ++   +  AL     ++ + T+ +V E+   +
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLI---TTKEITEENSGALD----KVYNETVKAVTEQVDQM  699

Query  822  RNNTAAAKLIEYTNHLTKEGVAARAAIEPLVLMVAPLAPHLAEELWKRL-GHDTSLAHGP  880
            + NTA A+L+ + N   KE+         +V ++AP+APHL+EELW+ L + + S++  P
Sbjct  700  KFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVP  759

Query  881  FPEADPQYLVEDTIEFPVQVNGKVRGKIVVaadadkaaleaaaladekVQAFLAGATPKK  940
             P  D   LVE+ +E+ VQ++GKV++K+VVA D  +  L+  ALA+EKVQA +AG    K
Sbjct  760  WPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIK  819

Query  941  VIVVPGRLVNLVV  953
            VI VP +LVN+V+
Sbjct  820  VIAVPNKLVNIVI  832


 Score =  131 bits (481),  Expect = 2e-31, Method: Compositional matrix adjust.
 Identities = 77/148 (53%), Positives = 100/148 (68%), Gaps = 11/148 (7%)

Query  28   IERAWQETWSDRGTFNVANPVGSLAPTDGSDVPADKMFVQDMFPYPSGDGLHVGHPLGYI  87
            IE  WQ  W+D  TF+            G+D +  K +  DMFPYPSG GLHVGHP GY 
Sbjct  9    IEPKWQAFWADNHTFKT-----------GTDASKPKFYALDMFPYPSGAGLHVGHPEGYT  57

Query  88   ATDVYARYYRMLGRNVLHALGFDAFGLPAEQYAVQTGTHPRTRTEANIVNFRRQLGRLGL  147
            ATD+ +R+ R  G+NVLH++G DAFGLPAEQYA++TG +P   T  NI NF+RQ+  LG+
Sbjct  58   ATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGF  117

Query  148  GHDTRRSFSTTDVDYYKWTQWIFLQIYN  175
            + D  R  +TTD +YYKWTQWIF ++Y+
Sbjct  118  SYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1373) leuS in NC_018101


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  530 bits (1999),  Expect = 2e-151, Method: Compositional matrix adjust.
 Identities = 355/742 (48%), Positives = 511/742 (69%), Gaps = 68/742 (9%)

Query  221  LVYRSNSTVNWCPGLGTVLANEEVTADGRSERGNFPVFRKNLSQWMMRITAYSDRLIDDL  280
            L Y ++  VNW   LGT +ANEEV +DG SERG +PV RK + QWM++ITAY++RL++DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  281  EVLDWPEKVKSMQRNWIGRSRGAEVDF--EAAGKTITVFTTRPDTLFGASYMVLAPEHEL  338
            E +DWPE +K MQRNWIG+S GA+V F    ++K +TVFTTRPDTLFGA+Y VLAPEH L
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  339  VDALVAAGTGSYEGIDARWTFGEadpasavaayrasiaaksDLERQE-NKEKTGVFLGVY  397
            VDA+ +++ +  E++                 Y+   + KSDL R +  KEKTGV  G Y
Sbjct  268  VDAITTSDQA--EAVAD---------------YKRQASLKSDLARTDLAKEKTGVWTGSY  310

Query  398  ATNPVNGEQIPVFIGDYVLTGYGTGAIMSVPAHDARDYEFATEFGLPIREVVAGGDVNVG  457
            A NPVNG ++PV I+DYVL++YGTGAIM+VPAHD RD EFA +F L I  V+ GG+V+ +
Sbjct  311  AINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEA  370

Query  458  PYVEPGTAINSANDRGLDINGLDKAEAIARVIEWLEAQGAGVEKIQYKLRDWLFARQRYW  517
            ++ E G  INS       ++GLDKA AIA+++EWLEA+G G E++ Y+LRDWLF+RQRYW
Sbjct  371  AFTEDGLHINSDF-----LDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYW  425

Query  518  GEPFPVVYDEDGVAHALPESMLPVELPEVEDYKPVSFDPDDADSEPQPPLAKATEWTTVE  577
            GEP+P++  EDG + A+PES LP+ LP   D +P         +  ++PLA+ T+W  +E
Sbjct  426  GEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTDW--LE  475

Query  578  LDLGDGPKTYTRDTNVMPQWAGSSWYQLRYIDPTNSEQFCDIENERYWTGPRGENdlggv  637
            +   DG K   R+TN MPQWAGSSWY LRYIDP N+E++ D E  + W           V
Sbjct  476  VTREDGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLP---------V  525

Query  638  dlyvggvEHAVLHLLYSRFWHKVLFDLGYVTSGEPYRRLFNQGYIQAFAYTDSRGVYVPA  697
            D+YVGG EHAVLHLLY+RFWHKVL+DLG V + EP+++LFNQG I + +Y DSRG  V++
Sbjct  526  DIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVAT  585

Query  698  AEVEEKDGKFFY--NGEEVNQEYGKMGKSLKNAVAPDEICSDFGADTLRVYEMAMGPLDT  755
              VE +DG FF    GEE++Q  +KM+KSLKN V PD++  ++GADTLRVYEM MGPLD+
Sbjct  586  DKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  756  SRPWATKDVIGAHRFLQRLWRLVVNEETGELSVTDASLTNDDLKALNRTIAGIRDDYQGL  815
            S +W+  ++ G+++FL+R+ RL+   E  E     ++L     K  N T+ ++ ++ + +
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLITTKEITE--ENSGALD----KVYNETVKAVTEQVDQM  699

Query  816  RINTVVAKAIEYVNYLTK------TYSKGAPREAVEPLAIMVAPVAPHIAEELWKRL-GH  868
            ++NT +A+ + +VN   K       Y+KG        +  ++AP APH++EELW+ L + 
Sbjct  700  KFNTAIAQLMVFVNAANKEDKLFSDYAKG--------FVQLIAPFAPHLGEELWQALTAS  751

Query  869  EETITFEQFPSYEEKWLKDDEVELPVQINGKVRARIMVPTDATQDQIVEIALAEPTVQSH  928
             E+I++   PSY+E  L +++VE+ VQI+GKV+A+++V+ D +++++ E+ALA+  VQ++
Sbjct  752  GESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAE  811

Query  929  LEGKNLFKQIVVPGRMVNLVIK  950
            + GK+++K I VP ++VN+VIK
Sbjct  812  IAGKDIIKVIAVPNKLVNIVIK  833


 Score =  140 bits (516),  Expect = 4e-34, Method: Compositional matrix adjust.
 Identities = 82/149 (56%), Positives = 102/149 (69%), Gaps = 10/149 (6%)

Query  21   GDIERTWQKFWIDNGTFNAPNPVGDLAVTGQKLPEDKLFVQDMFPYPSGAGLHVGHPLGY  80
              IE  WQ FW DN TF+          TG   +  K++  DMFPYPSGAGLHVGHP GY
Sbjct  7    TAIEPKWQAFWADNHTFK----------TGTDASKPKFYALDMFPYPSGAGLHVGHPEGY  56

Query  81   IATDVYARFNRMLGKNVLHTLGYDAFGLPAEQYAIQTGTHPRTTTMANIENMRRQLGALG  140
             ATD+ +RF+R  G NVLH +G DAFGLPAEQYA++TG +P   T  NI N +RQ+ ALG
Sbjct  57   TATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALG  116

Query  141  LGHDTRRSVATTDPEFYKWTQWIFLKIFN  169
            ++ D  R V TTDP++YKWTQWIF K+++
Sbjct  117  FSYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1374) leuS in NC_015683


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  530 bits (2000),  Expect = 2e-151, Method: Compositional matrix adjust.
 Identities = 355/742 (48%), Positives = 510/742 (69%), Gaps = 68/742 (9%)

Query  234  LVYRSNSTVNWCPGLGTVLANEEVTADGRSERGNFPVFRKNLSQWMMRITAYSDRLIDDL  293
            L Y ++  VNW   LGT +ANEEV +DG SERG +PV RK + QWM++ITAY++RL++DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  294  EMLDWPEKVKSMQRNWIGRSRGAEVDF--EAAGKTITVFTTRPDTLFGASYIVLAPEHEL  351
            E +DWPE +K MQRNWIG+S GA+V F    ++K +TVFTTRPDTLFGA+Y VLAPEH L
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  352  VDALVAAGTGSYEGIDARWTFGEadpasavaayrasiaaksDLERQE-NKEKTGVFLGVY  410
            VDA+ +++ +  E++                 Y+   + KSDL R +  KEKTGV  G Y
Sbjct  268  VDAITTSDQA--EAVAD---------------YKRQASLKSDLARTDLAKEKTGVWTGSY  310

Query  411  ATNPVNGEQIPVFIGDYVLTGYGTGAIMSVPAHDARDYEFATEFGLPIREVVAGGDVNVG  470
            A NPVNG ++PV I+DYVL++YGTGAIM+VPAHD RD EFA +F L I  V+ GG+V+ +
Sbjct  311  AINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEA  370

Query  471  PYVEPGTAINSANDRGLDINGLDKAEAIARVIEWLEAQGAGVEKIQYKLRDWLFARQRYW  530
            ++ E G  INS       ++GLDKA AIA+++EWLEA+G G E++ Y+LRDWLF+RQRYW
Sbjct  371  AFTEDGLHINSDF-----LDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYW  425

Query  531  GEPFPVVYDEDGVAHALPESMLPVELPEVEDYKPVSFDPDDADSEPQPPLAKATEWTTVE  590
            GEP+P++  EDG + A+PES LP+ LP   D +P         +  ++PLA+ T+W  +E
Sbjct  426  GEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTDW--LE  475

Query  591  LDLGDGPKTYTRDTNVMPQWAGSSWYQLRYIDPTNSEQFCDIENERYWTGPRGENdlggv  650
            +   DG K   R+TN MPQWAGSSWY LRYIDP N+E++ D E  + W           V
Sbjct  476  VTREDGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLP---------V  525

Query  651  dlyvggvEHAVLHLLYSRFWHKVLFDLGYVTSGEPYRRLFNQGYIQAFAYTDSRGVYVPA  710
            D+YVGG EHAVLHLLY+RFWHKVL+DLG V + EP+++LFNQG I + +Y DSRG  V++
Sbjct  526  DIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVAT  585

Query  711  AEVEEKDGKFFY--NGEEVNQEYGKMGKSLKNAVAPDEICSDFGADTLRVYEMAMGPLDT  768
              VE +DG FF    GEE++Q  +KM+KSLKN V PD++  ++GADTLRVYEM MGPLD+
Sbjct  586  DKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  769  SRPWATKDVIGAHRFLQRLWRLVVNEETGELSVTDASLTNDDLKALNRTIAGIRDDYQGL  828
            S +W+  ++ G+++FL+R+ RL+   E  E     ++L     K  N T+ ++ ++ + +
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLITTKEITE--ENSGALD----KVYNETVKAVTEQVDQM  699

Query  829  RINTVVAKAIEYVNYLTK------TYSKGAPREAVEPLAIMVAPVAPHIAEELWKRLGHE  882
            ++NT +A+ + +VN   K       Y+KG        +  ++AP APH++EELW+ L   
Sbjct  700  KFNTAIAQLMVFVNAANKEDKLFSDYAKG--------FVQLIAPFAPHLGEELWQALTAS  751

Query  883  G-TITFEQFPSYEEKWLKDDEVELPVQINGKVRARIMVPTDATQDQIVEIALAEPTVQSH  941
            G +I++   PSY+E  L +++VE+ VQI+GKV+A+++V+ D +++++ E+ALA+  VQ++
Sbjct  752  GESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAE  811

Query  942  LEGKNLFKQIVVPGRMVNLVIK  963
            + GK+++K I VP ++VN+VIK
Sbjct  812  IAGKDIIKVIAVPNKLVNIVIK  833


 Score =  140 bits (516),  Expect = 3e-34, Method: Compositional matrix adjust.
 Identities = 82/149 (56%), Positives = 102/149 (69%), Gaps = 10/149 (6%)

Query  34   GDIERTWQKFWIDNGTFNAPNPVGDLAVTGQKLPEDKLFVQDMFPYPSGAGLHVGHPLGY  93
              IE  WQ FW DN TF+          TG   +  K++  DMFPYPSGAGLHVGHP GY
Sbjct  7    TAIEPKWQAFWADNHTFK----------TGTDASKPKFYALDMFPYPSGAGLHVGHPEGY  56

Query  94   IATDVYARFNRMLGKNVLHTLGYDAFGLPAEQYAIQTGTHPRTTTMANIENMRRQLGALG  153
             ATD+ +RF+R  G NVLH +G DAFGLPAEQYA++TG +P   T  NI N +RQ+ ALG
Sbjct  57   TATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALG  116

Query  154  LGHDTRRSVATTDPEFYKWTQWIFLKIFN  182
            ++ D  R V TTDP++YKWTQWIF K+++
Sbjct  117  FSYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1375) leuS in NC_017027


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  530 bits (1999),  Expect = 2e-151, Method: Compositional matrix adjust.
 Identities = 354/866 (41%), Positives = 563/866 (66%), Gaps = 46/866 (5%)

Query  5    YRPDLIEAEVQQYWAENKTFKAIKDTNKPKYYCLSMFPYPSGR-LHMGHVRNYTIGDVVS  63
            Y    IE+  Q +WA+N TFK+  D++KPK+Y L MFPYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMNGKNVLQPMGWDAFGLPAEGAAIKNKTAPAKWTYENIDYMKNQLKILGFGFDWDR  123
            R++R +G NVL+PMGWDAFGLPAE  A+     PA  T ENI   K Q++ LGF++DWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVTTCKPDYYKWEQWFFTELYKKGLVYKKTSTVNWCPNDETVLANEQV-HEGCCWRCDTP  182
            EV T  P+YYKW QW+FT LY KGL Y     VNW  +  T +ANE+V  +G   R + P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VEQKEIPQWFIKITDYAEQLLGGLDHLPLWPDQVKTMQRNWIGRSEGVEITFQLANSEDN  242
            V +K + QW +KIT YAE+LL +L+++  WP+ +K MQRNWIG+S G ++TF++ +++ +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFFGVSY--VavaaahplaekaaENNPELAQFIQECK-NTKVAEAELATME  299
            +TV+TTRPDT+FG +Y  +A   A   A  ++++   +A++ ++   ++ +A ++LA  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGMATGVYAIHPLTGEKVPVWVANFVLMHYGTGAVMAVPGHDERDAEFARKYGLPLLNV  359
            K G+ TG YAI+P+ G  +PVW+A++VL  YGTGA+MAVP+HDERD EFA+++ L ++ V
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  360  IKPINGEPLPEHELPYCEHGILFNSGEFNGLDFDAAFNAIADKLEALGKGKRQVNYRLRD  419
            +   N E     E ++ E+G+ +NS+ ++GLD  +A+  + + LEA G G+ +V YRLRD
Sbjct  362  LEGGNVE-----EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMLTLENGEVVPAPLQDLPIELP--EDVVMDGV-KSPIKADPEWAKT  476
            W  SRQRYWG PIP++  E+G   + P  +LP+ LP   D+   G   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  TY-NGQPALKETDTFDTFMESSWYYARYTSPKFAEAMLDADEANYWLPVDQYIGGIEHAT  535
            T  +G  + +ET+T      SSWYY RY  P  +E + D +  + WLPVD Y+GG EHA 
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLLYFRFFHKLLRDAGFVTSDEPADKLLCQGMVLADAFYYTSPTNERIWVSPTEVTLER  595
            +HLLY RF HK+L D G V + EP +KL+ QGM+L+ ++      + R  + +T+    R
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEKR  591

Query  596  DEKGSILKAFDKEGRELVHSGMTKMSKSKNNGIDPQEMVEKYGADTVRLFMMFASPAEMT  655
            D  GS+   F+ E  E ++ + +KMSKS +N ++P+++VE+YGADT+R++ MF +P + +
Sbjct  592  D--GSF---FHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  656  LEWQESGVEGAKRFLGRLWNLVFEYNKHPAETAVEPTALSSAQKALRRDVHKTIAKVSDD  715
            + W E G+EG+++FL+R+  L+        E + E ++      AL +  + T+  V+++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLI-----TTKEITEENSG------ALDKVYNETVKAVTEQ  695

Query  716  IGRRQTFNTAIAAIMELMNKLTKAPLVEVQDRAIMAEALSAVVRMLYPITPHICFQLWKD  775
            +++ + FNTAIA +M ++N   K       +  + ++   + V+++ P++PH+  +LW+ 
Sbjct  696  VDQMK-FNTAIAQLMVFVNAANK-------EDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  776  L-GNTEVIDFAPWveadaaamvddeKLVVVQVNGKVRAKVTVPAEMSEDDIKQVALADSN  834
            L ++ E I + PW   D + +V+++  +VVQ++GKV+AK+ V+ ++S +++++VALA+ +
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  835  VAKHLEGLNIVKTIYVPGKLFSFVAK  860
            V  ++ G +I+K I VP KL ++V K
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVIK  833

1376) leuS in NC_011147


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  529 bits (1998),  Expect = 2e-151, Method: Compositional matrix adjust.
 Identities = 363/866 (42%), Positives = 551/866 (64%), Gaps = 48/866 (5%)

Query  5    YRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVVA  63
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKTLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q+++LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EIATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADELLRDLDKLDHWPDTVKTMQRNWIGRSEGVEITFDVKGYDNT  242
            V RK + QW +KITAYA+ LL DL+ +D WP+++K MQRNWIG+S G ++TF VK+ D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LIVYTTRPDTFMGATYLAVAAGHPlaqkaaannaelaaFVDECRNTKVAEAEMA----TM  298
            + V+TTRPDT+ GATY  +A+ H+L +  ++++   A  V + +      +++A    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEA--VADYKRQASLKSDLARTDLAK  300

Query  299  EKKGVDTGYKAIHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLTIKP  358
            EK GV TG  AI+P+ G E+PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L I P
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VILAADGSEPDLSEQALTEKGVLFNSGEFDGLAFEAAFNAIADKLAEKGVGERKVNYRLR  418
            V+        ++ E A+TE G+ +NS+ +DGL   +A+  + + L   GVG+ +V YRLR
Sbjct  361  VL-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  419  DWGVSRQRYWGAPIPMITQEDGTVLPTPEDQLPVILP--EDVVMDGIT-SPIKADPEWAK  475
            DW  SRQRYWG PIP+I  EDGT  + PE +LP++LP   D+   G   SP+    +W  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  476  TT-VNGMPALRETDTFDTFMESSWYYARYTCPQYQEGMLDSKAANYWLPVDIYIGGIEHA  534
             T  +G+ + RET+T      SSWYY RY  P+  E + D    + WLPVDIY+GG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  535  IMHLLYFRFFHKLMRDAGMVTSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVE  594
            ++HLLY RF HK++ D G+V + EP ++L+ QGM+L+ ++      + R  + + D +  
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEK  590

Query  595  RDEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADM  654
            RD  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D 
Sbjct  591  RD--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  655  TLEWQESGVEGANRFIKRVWKLVYEHTAKGPVAALNVDALSEDQKALRRDVHKTIAKVTD  714
            ++ W E G+EG+ +F+ RV +L+   T+K        +   E+  AL +  + T+  VT+
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLI---TTK--------EITEENSGALDKVYNETVKAVTE  694

Query  715  DIGRRQTFNTAIAAIMELMNKLAKAPQEGEQDRALLQEALQAVVRMLNPFTPHVCFTLWQ  774
            ++++ + FNTAIA +M ++N        ++++  L+ +  ++ V+++ PF+PH+   LWQ
Sbjct  695  QVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  775  ELGGEGD-IDNAPWPVADEQAMVENTTLVVVQVNGKVRGKITVAVDATEEQVRERAGQEH  833
             L + G+ I   PWP  DE  +VEN   +VVQ++GKV++K+ VA D + E+++E A  ++
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  834  LVAKYLDGVTVRKVIYVPGKLLNLVV  859
             V   + G  + KVI VP KL+N+V+
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVI  832

1377) leuS in NC_006511


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  529 bits (1998),  Expect = 2e-151, Method: Compositional matrix adjust.
 Identities = 363/866 (42%), Positives = 551/866 (64%), Gaps = 48/866 (5%)

Query  5    YRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVVA  63
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKTLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q+++LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EIATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADELLRDLDKLDHWPDTVKTMQRNWIGRSEGVEITFDVKGYDNT  242
            V RK + QW +KITAYA+ LL DL+ +D WP+++K MQRNWIG+S G ++TF VK+ D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LIVYTTRPDTFMGATYLAVAAGHPlaqkaaannaelaaFVDECRNTKVAEAEMA----TM  298
            + V+TTRPDT+ GATY  +A+ H+L +  ++++   A  V + +      +++A    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEA--VADYKRQASLKSDLARTDLAK  300

Query  299  EKKGVDTGYKAIHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLTIKP  358
            EK GV TG  AI+P+ G E+PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L I P
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VILAADGSEPDLSEQALTEKGVLFNSGEFDGLAFEAAFNAIADKLAEKGVGERKVNYRLR  418
            V+        ++ E A+TE G+ +NS+ +DGL   +A+  + + L   GVG+ +V YRLR
Sbjct  361  VL-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  419  DWGVSRQRYWGAPIPMITQEDGTVLPTPEDQLPVILP--EDVVMDGIT-SPIKADPEWAK  475
            DW  SRQRYWG PIP+I  EDGT  + PE +LP++LP   D+   G   SP+    +W  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  476  TT-VNGMPALRETDTFDTFMESSWYYARYTCPQYQEGMLDSKAANYWLPVDIYIGGIEHA  534
             T  +G+ + RET+T      SSWYY RY  P+  E + D    + WLPVDIY+GG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  535  IMHLLYFRFFHKLMRDAGMVTSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVE  594
            ++HLLY RF HK++ D G+V + EP ++L+ QGM+L+ ++      + R  + + D +  
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEK  590

Query  595  RDEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADM  654
            RD  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D 
Sbjct  591  RD--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  655  TLEWQESGVEGANRFIKRVWKLVYEHTAKGPVAALNVDALSEDQKALRRDVHKTIAKVTD  714
            ++ W E G+EG+ +F+ RV +L+   T+K        +   E+  AL +  + T+  VT+
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLI---TTK--------EITEENSGALDKVYNETVKAVTE  694

Query  715  DIGRRQTFNTAIAAIMELMNKLAKAPQEGEQDRALLQEALQAVVRMLNPFTPHVCFTLWQ  774
            ++++ + FNTAIA +M ++N        ++++  L+ +  ++ V+++ PF+PH+   LWQ
Sbjct  695  QVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  775  ELGGEGD-IDNAPWPVADEQAMVENTTLVVVQVNGKVRGKITVAVDATEEQVRERAGQEH  833
             L + G+ I   PWP  DE  +VEN   +VVQ++GKV++K+ VA D + E+++E A  ++
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  834  LVAKYLDGVTVRKVIYVPGKLLNLVV  859
             V   + G  + KVI VP KL+N+V+
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVI  832

1378) leuS in NC_006360


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  529 bits (1996),  Expect = 3e-151, Method: Compositional matrix adjust.
 Identities = 342/808 (43%), Positives = 536/808 (67%), Gaps = 68/808 (8%)

Query  1    MFPYPSASGLHLGHPIGYTASDIVARFKRLNGFDVLHPMGWDAFGLPAEQYAIKTGNHPG  60
            MFPYPS++GLH+GHP GYTA+DI++RFKR +G +VLHPMGWDAFGLPAEQYA+ TGN+P+
Sbjct  39   MFPYPSGAGLHVGHPEGYTATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPA  98

Query  61   EFTKRNIENFKKQIISFGFSYDWDKEINTSDPEFYVQTQWIFKLLYKANLAEIREVEVNW  120
            EFT  NI NFK+QI ++GFSYDWD+E+NT+DP++Y  TQWIF  LY   LA   EV VNW
Sbjct  99   EFTAENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNW  158

Query  121  CPELGTVLANEELKREKNGALVSERGNFPVILKKMKQWVLKITEYAQKLLDGLDQVDFPD  180
              ELGT +ANEE+  +      SERG +PV+ K M+QW+LKIT YA++LL++L++VD P+
Sbjct  159  VEELGTAIANEEVLPDGT----SERGGYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPE  214

Query  181  SLKALQkkwigkskgwkikFLIEKTGEFLEIFTTKIETFYGVSFLALAPLHNFAQKLAKN  240
            S+K +Q++WIGKS G ++ F +  T+  + +FTT+ +T++G ++  LAP H + + ++ +
Sbjct  215  SIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTS  274

Query  241  N--EKISQFIEQNSFSS----PKLQSKMTGIFTGLYAIHPLNSSKIPIYIANYVLNNYAT  294
            +  E ++++  Q S+ S      L    TG+ TG YAI+P+N+  +P+ IA+YVL +Y+T
Sbjct  275  DQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGT  334

Query  295  SAIMGVPGHNLADLEFAQIFQIDYVKVIN----------QENLLINSAEFSGLTIKDGAN  344
            +AIM+VP+H+  D EFA+ F++D + V++          ++ L INS  + GL    +  
Sbjct  335  GAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIA  394

Query  345  SIFNKLNSMNLVQKTTIFRLKDWVFSRQRYWGEPFP-VYFDEKGKIYLEEKIVE--LPHT  401
             + + L++  + +    +RL+DW+FSRQRYWGEP+P +  ++     + E  +   LP T
Sbjct  395  KMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVT  454

Query  402  DKIMPSGDGQSPLASIKDWVFFEK-NGKYYRRETNTMPQWSGSSWYYLAFILKEKDKYLP  460
              I PSG G+SPLA++ DW+   + +G   RRETNTMPQW+GSSWYYL +I  ++   L+
Sbjct  455  KDIRPSGTGESPLANVTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLA  514

Query  461  LDSKIAYDKFKKWLPVDLYIGGQEHAVGHLIYSRFWHKVLFDAGIVPNSEPFQKIIHQGM  520
             +     + +K+WLPVD+Y+GG EHAV HL+Y+RFWHKVL+D G+VP  EPFQK+++QGM
Sbjct  515  DE-----ELLKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGM  569

Query  521  LLGSD---------------------------------GQKMSKSKGNTINPTEMIDKFG  547
            +LG+                                    KMSKS  N +NP ++++++G
Sbjct  570  ILGTSYRDSRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYG  629

Query  548  ADTIRIFLMFMGPIGDLRLWDENGVVSIFNWIQRVQRTILANYEIDPELEKDYEFTYFFN  607
            ADT+R++ MFMGP++    W E+G+ +  + ++RV R I ++ EI  E     +  Y  N
Sbjct  630  ADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTK-EITEENSGALDKVY--N  686

Query  608  NFVFEITNLIETFKFNVAISKLMIYINFLNKKQKIPSKNYLTDFLIIFSVFAPHTAEELL  667
            + V  +T+ ++  KFN AI++LM+++N  NK +K+ S +Y  +F+ +++ FAPH +EEL 
Sbjct  687  ETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFS-DYAKGFVQLIAPFAPHLGEELW  745

Query  668  EKL--GQKPLNFQIWPQFDRSKIFKNTFHLPVSINGKNRGILELTDEKSQEEIIEIAKKD  725
            + L  +  ++++  WP +D SK+  N  ++ V I+GK ++ L ++ + S+EE+ E+A  +
Sbjct  746  QALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALAN  805

Query  726  YKIRNYLQNKQIIKVIYIPRKILNFILK  753
             K++  +  K+IIKVI +P K++N+++K
Sbjct  806  EKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

1379) TCCBUS3UF1_22230 in NC_017278


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  529 bits (1996),  Expect = 3e-151, Method: Compositional matrix adjust.
 Identities = 375/883 (43%), Positives = 548/883 (63%), Gaps = 62/883 (7%)

Query  4    YNPHAIEPKWQRFWKEKGFMKAQEVPGAKGKQYVLVMFPYPSG-DLHMGHLKNYTMGDVL  62
            Y+  AIEPKWQ FW ++   K+    ++K K Y L MFPYPSG +LH+GH   YT  D+L
Sbjct  4    YDHTAIEPKWQAFWADNHTFKT-GTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDIL  62

Query  63   ARFRRVQGYQVLHPMGWDAFGLPAENAALKFGLHPRDWTYQNIRQAKESLELMGILYDWD  122
            +RF+R QG +VLHPMGWDAFGLPAE+ A+  G +P + T +NI + K  ++ +G+ YDWD
Sbjct  63   SRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWD  122

Query  123  REVTTCEPDYYRFNQWIFLKMWEKGLAYRAKGLVNWCPKCQTVLANEQVVEGRCWRHEDT  182
            REV T +P+YY+  QWIF K+ EKGLAY A   VNW     T +ANE+V+ +    + + 
Sbjct  123  REVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGY  182

Query  183  PVEKRELEQWYLRITAYADRLLEDLEGLRWPEKVKAMQRAWIGRSEGAEIHFPVAEGEER  242
            PV ++ + QW L+ITAYA+RLLEDLE + WPE +K MQR WIG+S GA++ F V + +  
Sbjct  183  PVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  IPVFTTRPDTLFGATFLVLAPEHPLTLRLAAPERRAEVQAYVEAAKRKTEIERQAEGREK  302
            + VFTTRPDTLFGAT+ VLAPEH+L   ++++++   V  Y   A  K+++ R   ++EK
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEK  302

Query  303  TGVFLGAYALNPATGARIPIWTADYVLFGYGTGAIMGVPGHDQRDFEFAKKFGLPIKKVI  362
            TGV  G+YA+NP  G  +P+W ADYVL +YGTGAIM+VP+HD+RD EFAK+F L I  V+
Sbjct  303  TGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL  362

Query  363  erpgeplpeplerAYEEPGVMVNSGPFDGTPSEEGKGRVVAWLEERGLGKRRITYRLRDW  422
                    +  E A+ E G+ +NS+ +DG     + +++V WLE  G+G+  +TYRLRDW
Sbjct  363  -----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDW  417

Query  423  LISRQRYWGTPIPMVHCPACGvvpvpeeelpvllpdlkdvedIRPKGK--SPLEAHPEFY  480
            L+SRQRYWG PIP++H              + L   L    DIRP G   SPL    +  
Sbjct  418  LFSRQRYWGEPIPIIHWEDGT---STAVPESELPLVLPVTKDIRPSGTGESPLANVTDWL  474

Query  481  ETTCPRCGGPAKRdtdtmdtffdSSWYYLRYTDPKNGRLPFDPEKARFWMPVDQYIGGVE  540
            E T    G  ++R+T+TM    +SSWYYLRY DP N     D E  + W+PVD Y+GG E
Sbjct  475  EVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAE  533

Query  541  HAVLHLLYSRFFTKFLHDLGLVEVEEPFLGLFTQGMVLAWTDFGPVEVEGERVRLPEPTR  600
            HAVLHLLY+RF  K L DLG+V   EPF  LF QGM+L+ T +      + R  L    +
Sbjct  534  HAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILG-TSY-----RDSRGALVATDK  587

Query  601  IQLEMAQGELSLEDVRKMGAELRPHADGSLHLWKPAVMSKSKGNGVMVGPFVREEGADIA  660
            ++             ++ G+ ++ +++  L+   PA MSKS  N V  +  V + GAD  
Sbjct  588  VE-------------KRDGSFFHVETGEELEQ-APAKMSKSLKNVVNPDDVVEQYGADTL  633

Query  661  RITILFAAPPENEMVWTEEGVQGAWRFLNRVWRRVAEDKEALLATSGRFQAEALEGADKE  720
            R+  +F +P +  + W+EEG++G+++FL+RV R         L T+  +  E   + DK 
Sbjct  634  RVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYR---------LITTKEITEENSGALDK-  683

Query  721  LYGKLHATLKKVTEDLEALRFNTAIAALMEFLNALYDYRKVAPVTPVYRTAIRYYLQMLF  780
            +Y   + T+K VTE+++ ++FNTAIA LM F+NA            ++    + ++Q++ 
Sbjct  684  VY---NETVKAVTEQVDQMKFNTAIAQLMVFVNA------ANKEDKLFSDYAKGFVQLIA  734

Query  781  PFAPHLAEELWHWF--WPDSLFQAGWPELDEKALERELVEVAVQVNGRVRGTIQIPKDAP  838
            PFAPHL+EELW+ +    +S+    WP  DE  L  + VE+ VQ++G+V++ + ++KD +
Sbjct  735  PFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLS  794

Query  839  ----LEVALAEARKVRNVQAHLEGKEVLKEIYVPGKILNLVVR  877
                 EVALA+ +    VQA++ GK+++K I VP K++N+V++
Sbjct  795  REELQEVALANEK----VQAEIAGKDIIKVIAVPNKLVNIVIK  833

1380) leuS in NC_011294


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  529 bits (1996),  Expect = 3e-151, Method: Compositional matrix adjust.
 Identities = 361/866 (42%), Positives = 551/866 (64%), Gaps = 48/866 (5%)

Query  5    YRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVVA  63
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKTLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q+++LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EIATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADELLRDLDKLDHWPDTVKTMQRNWIGRSEGVEITFDVKGYDNT  242
            V RK + QW +KITAYA+ LL DL+ +D WP+++K MQRNWIG+S G ++TF VK+ D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGATYLAVAAGHPlaqkaaannaelaaFIDECRNTKVAEAEMA----TM  298
            +TV+TTRPDT+ GATY  +A+ H+L +  ++++   A  + + +      +++A    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEA--VADYKRQASLKSDLARTDLAK  300

Query  299  EKKGVDTGFKATHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLTIKP  358
            EK GV TG  A +P+ G E+PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L I P
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VILAADGSEPDLSEQALTEKGVLFNSGEFDGLAFEAAFNAIADKLAEKGVGERKVNYRLR  418
            V+        ++ E A+TE G+ +NS+ +DGL   +A+  + + L   GVG+ +V YRLR
Sbjct  361  VL-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  419  DWGVSRQRYWGAPIPMVTLEDGTVLPTPEDQLPVILP--EDVVMDGIT-SPIKADPEWAK  475
            DW  SRQRYWG PIP++  EDGT  + PE +LP++LP   D+   G   SP+    +W  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  476  TT-VNGMPALRETDTFDTFMESSWYYARYTCPQYQEGMLDSKAANYWLPVDIYIGGIEHA  534
             T  +G+ + RET+T      SSWYY RY  P+  E + D    + WLPVDIY+GG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  535  IMHLLYFRFFHKLMRDAGMVTSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVE  594
            ++HLLY RF HK++ D G+V + EP ++L+ QGM+L+ ++      + R  + + D +  
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEK  590

Query  595  RDEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADM  654
            RD  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D 
Sbjct  591  RD--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  655  TLEWQESGVEGANRFIKRVWKLVYEHTAKGPVAALNVDALSEDQKALRRDVHKTIAKVTD  714
            ++ W E G+EG+ +F+ RV +L+   T+K        +   E+  AL +  + T+  VT+
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLI---TTK--------EITEENSGALDKVYNETVKAVTE  694

Query  715  DIGRRQTFNTAIAAIMELMNKLAKAPQEGEQDRALLQEALQAVVRMLNPFTPHVCFTLWQ  774
            ++++ + FNTAIA +M ++N        ++++  L+ +  ++ V+++ PF+PH+   LWQ
Sbjct  695  QVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  775  ELGGEGD-IDNAPWPVADEQAMVENTTLVVVQVNGKVRGKITVAVDATEEQVRERAGQEH  833
             L + G+ I   PWP  DE  +VEN   +VVQ++GKV++K+ VA D + E+++E A  ++
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  834  LVAKYLDGVTVRKVIYVPGKLLNLVV  859
             V   + G  + KVI VP KL+N+V+
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVI  832

1381) STY0699 in NC_003198


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  529 bits (1996),  Expect = 3e-151, Method: Compositional matrix adjust.
 Identities = 361/866 (42%), Positives = 552/866 (64%), Gaps = 48/866 (5%)

Query  5    YRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVVA  63
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQHMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKTLGFGYDWSR  123
            R+++  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q+++LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EIATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADELLRDLDKLDHWPDTVKTMQRNWIGRSEGVEITFDVKGYDNT  242
            V RK + QW +KITAYA+ LL DL+ +D WP+++K MQRNWIG+S G ++TF VK+ D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGATYLAVAAGHPlaqkaaannaelaaFIDECRNTKVAEAEMA----TM  298
            +TV+TTRPDT+ GATY  +A+ H+L +  ++++   A  + + +      +++A    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEA--VADYKRQASLKSDLARTDLAK  300

Query  299  EKKGVDTGYKAIHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLTIKP  358
            EK GV TG  AI+P+ G E+PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L I P
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VILAADGSEPDLSEQALTEKGVLFNSGEFDGLAFEAAFNAIADKLAEKGVGERKVNYRLR  418
            V+        ++ E A+TE G+ +NS+ +DGL   +A+  + + L   GVG+ +V YRLR
Sbjct  361  VL-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  419  DWGVSRQRYWGAPIPMVTLEDGTVLPTPEDQLPVILP--EDVVMDGIT-SPIKADPEWAK  475
            DW  SRQRYWG PIP++  EDGT  + PE +LP++LP   D+   G   SP+    +W  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  476  TT-VNGMPALRETDTFDTFMESSWYYARYTCPQYQEGMLDSKAANYWLPVDIYIGGIEHA  534
             T  +G+ + RET+T      SSWYY RY  P+  E + D    + WLPVDIY+GG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  535  IMHLLYFRFFHKLMRDAGMVTSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVE  594
            ++HLLY RF HK++ D G+V + EP ++L+ QGM+L+ ++      + R  + + D +  
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEK  590

Query  595  RDEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADM  654
            RD  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D 
Sbjct  591  RD--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  655  TLEWQESGVEGANRFIKRVWKLVYEHTAKGPVAALNVDALSEDQKALRRDVHKTIAKVTD  714
            ++ W E G+EG+ +F+ RV +L+   T+K        +   E+  AL +  + T+  VT+
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLI---TTK--------EITEENSGALDKVYNETVKAVTE  694

Query  715  DIGRRQTFNTAIAAIMELMNKLAKAPQEGEQDRALLQEALQAVVRMLNPFTPHVCFTLWQ  774
            ++++ + FNTAIA +M ++N        ++++  L+ +  ++ V+++ PF+PH+   LWQ
Sbjct  695  QVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  775  ELGGEGD-IDNAPWPVADEQAMVENTTLVVVQVNGKVRGKITVAVDATEEQVRERAGQEH  833
             L + G+ I   PWP  DE  +VEN   +VVQ++GKV++K+ VA D + E+++E A  ++
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  834  LVAKYLDGVTVRKVIYVPGKLLNLVV  859
             V   + G  + KVI VP KL+N+V+
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVI  832

1382) STBHUCCB_23460 in NC_016832


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  529 bits (1996),  Expect = 3e-151, Method: Compositional matrix adjust.
 Identities = 361/866 (42%), Positives = 552/866 (64%), Gaps = 48/866 (5%)

Query  5    YRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVVA  63
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQHMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKTLGFGYDWSR  123
            R+++  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q+++LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EIATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADELLRDLDKLDHWPDTVKTMQRNWIGRSEGVEITFDVKGYDNT  242
            V RK + QW +KITAYA+ LL DL+ +D WP+++K MQRNWIG+S G ++TF VK+ D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGATYLAVAAGHPlaqkaaannaelaaFIDECRNTKVAEAEMA----TM  298
            +TV+TTRPDT+ GATY  +A+ H+L +  ++++   A  + + +      +++A    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEA--VADYKRQASLKSDLARTDLAK  300

Query  299  EKKGVDTGYKAIHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLTIKP  358
            EK GV TG  AI+P+ G E+PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L I P
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VILAADGSEPDLSEQALTEKGVLFNSGEFDGLAFEAAFNAIADKLAEKGVGERKVNYRLR  418
            V+        ++ E A+TE G+ +NS+ +DGL   +A+  + + L   GVG+ +V YRLR
Sbjct  361  VL-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  419  DWGVSRQRYWGAPIPMVTLEDGTVLPTPEDQLPVILP--EDVVMDGIT-SPIKADPEWAK  475
            DW  SRQRYWG PIP++  EDGT  + PE +LP++LP   D+   G   SP+    +W  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  476  TT-VNGMPALRETDTFDTFMESSWYYARYTCPQYQEGMLDSKAANYWLPVDIYIGGIEHA  534
             T  +G+ + RET+T      SSWYY RY  P+  E + D    + WLPVDIY+GG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  535  IMHLLYFRFFHKLMRDAGMVTSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVE  594
            ++HLLY RF HK++ D G+V + EP ++L+ QGM+L+ ++      + R  + + D +  
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEK  590

Query  595  RDEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADM  654
            RD  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D 
Sbjct  591  RD--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  655  TLEWQESGVEGANRFIKRVWKLVYEHTAKGPVAALNVDALSEDQKALRRDVHKTIAKVTD  714
            ++ W E G+EG+ +F+ RV +L+   T+K        +   E+  AL +  + T+  VT+
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLI---TTK--------EITEENSGALDKVYNETVKAVTE  694

Query  715  DIGRRQTFNTAIAAIMELMNKLAKAPQEGEQDRALLQEALQAVVRMLNPFTPHVCFTLWQ  774
            ++++ + FNTAIA +M ++N        ++++  L+ +  ++ V+++ PF+PH+   LWQ
Sbjct  695  QVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  775  ELGGEGD-IDNAPWPVADEQAMVENTTLVVVQVNGKVRGKITVAVDATEEQVRERAGQEH  833
             L + G+ I   PWP  DE  +VEN   +VVQ++GKV++K+ VA D + E+++E A  ++
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  834  LVAKYLDGVTVRKVIYVPGKLLNLVV  859
             V   + G  + KVI VP KL+N+V+
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVI  832

1383) leuS in NC_021176


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  529 bits (1996),  Expect = 3e-151, Method: Compositional matrix adjust.
 Identities = 361/866 (42%), Positives = 552/866 (64%), Gaps = 48/866 (5%)

Query  5    YRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVVA  63
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQHMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKTLGFGYDWSR  123
            R+++  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q+++LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EIATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADELLRDLDKLDHWPDTVKTMQRNWIGRSEGVEITFDVKGYDNT  242
            V RK + QW +KITAYA+ LL DL+ +D WP+++K MQRNWIG+S G ++TF VK+ D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGATYLAVAAGHPlaqkaaannaelaaFIDECRNTKVAEAEMA----TM  298
            +TV+TTRPDT+ GATY  +A+ H+L +  ++++   A  + + +      +++A    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEA--VADYKRQASLKSDLARTDLAK  300

Query  299  EKKGVDTGYKAIHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLTIKP  358
            EK GV TG  AI+P+ G E+PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L I P
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VILAADGSEPDLSEQALTEKGVLFNSGEFDGLAFEAAFNAIADKLAEKGVGERKVNYRLR  418
            V+        ++ E A+TE G+ +NS+ +DGL   +A+  + + L   GVG+ +V YRLR
Sbjct  361  VL-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  419  DWGVSRQRYWGAPIPMVTLEDGTVLPTPEDQLPVILP--EDVVMDGIT-SPIKADPEWAK  475
            DW  SRQRYWG PIP++  EDGT  + PE +LP++LP   D+   G   SP+    +W  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  476  TT-VNGMPALRETDTFDTFMESSWYYARYTCPQYQEGMLDSKAANYWLPVDIYIGGIEHA  534
             T  +G+ + RET+T      SSWYY RY  P+  E + D    + WLPVDIY+GG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  535  IMHLLYFRFFHKLMRDAGMVTSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVE  594
            ++HLLY RF HK++ D G+V + EP ++L+ QGM+L+ ++      + R  + + D +  
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEK  590

Query  595  RDEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADM  654
            RD  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D 
Sbjct  591  RD--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  655  TLEWQESGVEGANRFIKRVWKLVYEHTAKGPVAALNVDALSEDQKALRRDVHKTIAKVTD  714
            ++ W E G+EG+ +F+ RV +L+   T+K        +   E+  AL +  + T+  VT+
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLI---TTK--------EITEENSGALDKVYNETVKAVTE  694

Query  715  DIGRRQTFNTAIAAIMELMNKLAKAPQEGEQDRALLQEALQAVVRMLNPFTPHVCFTLWQ  774
            ++++ + FNTAIA +M ++N        ++++  L+ +  ++ V+++ PF+PH+   LWQ
Sbjct  695  QVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  775  ELGGEGD-IDNAPWPVADEQAMVENTTLVVVQVNGKVRGKITVAVDATEEQVRERAGQEH  833
             L + G+ I   PWP  DE  +VEN   +VVQ++GKV++K+ VA D + E+++E A  ++
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  834  LVAKYLDGVTVRKVIYVPGKLLNLVV  859
             V   + G  + KVI VP KL+N+V+
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVI  832

1384) leuS in NC_004631


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  529 bits (1996),  Expect = 3e-151, Method: Compositional matrix adjust.
 Identities = 361/866 (42%), Positives = 552/866 (64%), Gaps = 48/866 (5%)

Query  5    YRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVVA  63
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQHMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKTLGFGYDWSR  123
            R+++  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q+++LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EIATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADELLRDLDKLDHWPDTVKTMQRNWIGRSEGVEITFDVKGYDNT  242
            V RK + QW +KITAYA+ LL DL+ +D WP+++K MQRNWIG+S G ++TF VK+ D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGATYLAVAAGHPlaqkaaannaelaaFIDECRNTKVAEAEMA----TM  298
            +TV+TTRPDT+ GATY  +A+ H+L +  ++++   A  + + +      +++A    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEA--VADYKRQASLKSDLARTDLAK  300

Query  299  EKKGVDTGYKAIHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLTIKP  358
            EK GV TG  AI+P+ G E+PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L I P
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VILAADGSEPDLSEQALTEKGVLFNSGEFDGLAFEAAFNAIADKLAEKGVGERKVNYRLR  418
            V+        ++ E A+TE G+ +NS+ +DGL   +A+  + + L   GVG+ +V YRLR
Sbjct  361  VL-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  419  DWGVSRQRYWGAPIPMVTLEDGTVLPTPEDQLPVILP--EDVVMDGIT-SPIKADPEWAK  475
            DW  SRQRYWG PIP++  EDGT  + PE +LP++LP   D+   G   SP+    +W  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  476  TT-VNGMPALRETDTFDTFMESSWYYARYTCPQYQEGMLDSKAANYWLPVDIYIGGIEHA  534
             T  +G+ + RET+T      SSWYY RY  P+  E + D    + WLPVDIY+GG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  535  IMHLLYFRFFHKLMRDAGMVTSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVE  594
            ++HLLY RF HK++ D G+V + EP ++L+ QGM+L+ ++      + R  + + D +  
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEK  590

Query  595  RDEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADM  654
            RD  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D 
Sbjct  591  RD--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  655  TLEWQESGVEGANRFIKRVWKLVYEHTAKGPVAALNVDALSEDQKALRRDVHKTIAKVTD  714
            ++ W E G+EG+ +F+ RV +L+   T+K        +   E+  AL +  + T+  VT+
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLI---TTK--------EITEENSGALDKVYNETVKAVTE  694

Query  715  DIGRRQTFNTAIAAIMELMNKLAKAPQEGEQDRALLQEALQAVVRMLNPFTPHVCFTLWQ  774
            ++++ + FNTAIA +M ++N        ++++  L+ +  ++ V+++ PF+PH+   LWQ
Sbjct  695  QVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  775  ELGGEGD-IDNAPWPVADEQAMVENTTLVVVQVNGKVRGKITVAVDATEEQVRERAGQEH  833
             L + G+ I   PWP  DE  +VEN   +VVQ++GKV++K+ VA D + E+++E A  ++
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  834  LVAKYLDGVTVRKVIYVPGKLLNLVV  859
             V   + G  + KVI VP KL+N+V+
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVI  832

1385) MELS_2130 in NC_015873


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  529 bits (1996),  Expect = 3e-151, Method: Compositional matrix adjust.
 Identities = 341/835 (41%), Positives = 520/835 (63%), Gaps = 75/835 (8%)

Query  4    YIPQEIEKKWQHVWEESKCDCCSEDNGKPPYYVLEMFPYPSG-NLHMGHVRNYTIGDVIA  62
            Y    IE KWQ  W ++     + D +KP +Y L+MFPYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYRRMNGYNVLHPMGYDAFGMPAENAAIKHNIPPAEWTYSNIANMTRQQKALGLSYDWDR  122
            R++R +G NVLHPMG DAFG+PAE+ A+     PAE T  NIAN  RQ +ALG+SYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVATCHEKYYKWTQWIFELLYKRGLAYRKEAKVNWCEKCNTVLANEQVI-EGKCWRCDTP  181
            EV T + +YYKWTQWIF  LY +GLAY  E  VNW E   T +ANE+V+ +G   R + P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VVKKDLKQWFFKITDYADRLLEDLKLLPGWPERVKTMQKNWIGRSEGLEFSFDIPSLKEK  241
            VV+K ++QW +KIT YA+RLLEDL  + +WPE +K MQ+NWIG+S G + +F +      
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  242  VAVYTTRPDTIYGVTFVVLPPEHPLVHKLLENNPKKAELEAFCEKVRNTSDIERTSTESE  301
             +V+TTRPDT++G T+ VL+PEH+LV+ +  ++   A +  +  +    SD+ RT    E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEA-VADYKRQASLKSDLARTDLAKE  301

Query  302  KVGMYTGIDCVHPLTGKSVQIWITNYVLYDYGTGAVMGVPTGDQRDWMFATKYNIPKIIT  361
            K G+ TG   ++P+ GK + +WI++YVL  YGTGA+M+VP+ D+RDW FA ++N+  I  
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  362  LQPKDHELKLEEMDHAYEDKDGVLVNAGPFTGMEMHKAMKAIIDYMEEKGLGKRRVNYRL  421
            L+  + E      + A+ + DG+ +N++ + G++   A+  +++ +E  G+G+  V YRL
Sbjct  362  LEGGNVE------EAAFTE-DGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRL  414

Query  422  RDWLISRQRYWGAPIPIIYCPKCGEQLVPEDQLPVKLP--EDVKFTAGAVSPLATSEHFV  479
            RDWL+SRQRYWG PIPII         VPE +LP+ LP   D++ ++ + SPLA   + +
Sbjct  415  RDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWL  474

Query  480  HCTCPKCGGPATRETDTIDTFVCSSWYYLRYTDARNDEKAWDPEKANHWMNVDQYIGGIE  539
            + T    G  + RET+T+     SSWYYLRY D++N EK  D E  ++W+ VD Y+GG E
Sbjct  475  EVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAE  533

Query  540  HAILHLMYSRFFMKVFYDAGLVDNVEPFERLLTQGMVL----------------------  577
            HA+LHL+Y+RF  KV+YD G+V   EPF++L+ QGM+L                      
Sbjct  534  HAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDG  593

Query  578  ------------LDGSKMSKSKGNIVSPEEIIAKYGADTARLFILFAAPPERDLAWSDQG  625
                           +KMSKS  N+V+P++++ +YGADT R++ +F +P +  +AWS++G
Sbjct  594  SFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEG  653

Query  626  VEGSYRFLNRVWRIVHQFQDLAKAGQDGTD--YTEAEKELRFQEFKALAKVTEDIRGTDG  683
            +EGS +FL+RV R++   ++++    ++ D  Y E+         KA++   ++++    
Sbjct  654  LEGSRKFLDRVYRLITT-KEITEENSGALDKVYNET--------VKAVTEQVDQMK----  700

Query  684  NYGLNTAVSSIMEYVNAMHAYVGANKTIHKAVALEANKNLLKILAPFTPHITEELWQ-LC  742
               +NTA++ +M +VNA +     +K +      +  K +++++APF+PH+ EELWQ L 
Sbjct  701  ---FNTAIAQLMVFVNAANK---EDKLFS-----DYAKGFVQLIAPFAPHLGEELWQALT  749

Query  743  GFEGSVHAQDWPEVDKSALVVDEIELPVQINGKVRDRLTVAVDIDKDALQEQVLA  797
            +   S+    WP  D S LV +++E+ VQI+GKV+ +L VA D+ ++ LQE  LA
Sbjct  750  ASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALA  804

1386) leuS in NC_004578


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  529 bits (1996),  Expect = 3e-151, Method: Compositional matrix adjust.
 Identities = 354/874 (41%), Positives = 553/874 (64%), Gaps = 56/874 (6%)

Query  4    LYQPREIEAAAQTFWDEQKSFEVSEQPGKETFYCLSMFPYPSGK-LHMGHVRNYTIGDVI  62
            +Y+   IE+  Q+FW ++ +F  + +++K  FY L MFPYPSG  LH+GH   YT  D++
Sbjct  3    FYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDIL  62

Query  63   SRYQRMLGKNVLQPLGWDAFGMPAENAAIDNNVAPAKWTYENIAYMKNQLKSLGLAVDWS  122
            SR++R  G NVL+P+GWDAFG+PAE+ A+D    PA  T ENIA  K Q+++LG++ DW 
Sbjct  63   SRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWD  122

Query  123  REVTTCKPDYYRWEQWLFTRLFEKGVIYRKNGTVNWDPIDQTVLANEQVI-DGRGWRSGA  181
            REV T  P+YY+W QW+FT+L+EKG+ Y  +  VNW     T +ANE+V+ DG + R+G 
Sbjct  123  REVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGY  182

Query  182  LIEKREIPMYYFKITAYADELLESLDELPGWPEQVKTMQRNWIGRSRGMEVQFPYDQASI  241
             + ++ +    +KITAYA+ LLE L+E+ +WPE +K MQRNWIG+S G +V F   ++  
Sbjct  183  PVVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTD-  240

Query  242  GEAGALKVFTTRPDTLMGATYVAVAAEHPLATLAAQGNPALQAFIDECKGGSVAEADVA-  300
                 + VFTTRPDTL GATY  +A+EH+L    + ++ A    + + K  +   +D+A 
Sbjct  241  ---KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQA--EAVADYKRQASLKSDLAR  295

Query  301  ---TQEKKGQPTSLFVEHPLTGEKLPVWVANYVLMHYGDGAVMAVPAHDERDFEFASKYD  357
               ++EK G  T+ +  +P+ G  +PVW+A+YVL  YG GA+MAVPAHDERD EFA +++
Sbjct  296  TDLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFN  355

Query  358  LPIKPVVRTSAGDETPAPWQAEYNEQGPLINSGEFTGLHFQDAFDAIEAALVKKALGQSR  417
            L I PV+  +  +E++      + E+G  INS+ + GL+   A+  +   L   ++G+  
Sbjct  356  LDIIPVLEGGNVEEAA------FTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNEN  409

Query  418  TQFRLRDWGISRQRYWGCPIPIVHCDTCGDVPVPEDQLPVILP--EDVVPDGAG-SPLAR  474
              +RLRDW +SRQRYWG PIPI+H +     +VPE +LP++LP   D+ P G+G SPLA 
Sbjct  410  VTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLAN  469

Query  475  MPQFYECSCPKCGAPAKRETDTMDTFVESSWYYARYASPHYEGGLVEPNAANHWLPVDQY  534
            + +  E +    G  ++RET+TM     SSWYY RY  PH    L + +  ++WLPVD Y
Sbjct  470  VTDWLEVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIY  528

Query  535  IGGIEHAILHLLYARFFHKLMRDEGLVTSNEPFKNLLTQGMVNAETYFRMETSGKKTWIN  594
            +GG EHA+LHLLYARF HK++ D G+V ++EPF++L+ QGM+ + +Y   ++ G    + 
Sbjct  529  VGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY--RDSRGA---LV  583

Query  595  PADVTLERDAKAKVISATLTSDGLPVEIGGTEKMSKSKKNGIDPQTMIDQYGADTCRLFM  654
            ++D    RD+    +    T++ L     +  KMSKS KN ++P+ +++QYGADT R++ 
Sbjct  584  ATDKVEKRDGS---FFHVETGEELE---QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYE  637

Query  655  MFASPPDMSLEWSDSGVEGSHRFLRRVWRLAQA-HVGQGASGSLDIAALTDEQKAVRRSI  713
            MF +P D S+ WS+ G+EGS++FL RV RL  + ++ +  SG+LD            +  
Sbjct  638  MFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALD------------KVY  685

Query  714  HQAIKQASQDIGQNQKFNTAVAQVMTLMNVLEKAPQATPQDRALLQEGLETVTLLLAPIT  773
            ++++K  +++++Q  KFNTA+AQ+M ++N  +K       +  L+ +       L+AP++
Sbjct  686  NETVKAVTEQVDQ-MKFNTAIAQLMVFVNAANK-------EDKLFSDYAKGFVQLIAPFA  737

Query  774  PHISHELWTQL-GHNEPVIDAGWPVFDAHALVQDSLQLVIQVNGKLRGHIEMPasasree  832
            PH+++ELW  L +  E++    WP +D   LV++ +++V+Q++GK+++ + ++   SREE
Sbjct  738  PHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREE  797

Query  833  veaaarINENVLRFTDGLTIRKVIVVPGKLVNIV  866
            ++  A  NE+V     G  I KVI VP KLVNIV
Sbjct  798  LQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIV  831

1387) leuS in NC_006370


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  529 bits (1995),  Expect = 4e-151, Method: Compositional matrix adjust.
 Identities = 367/867 (43%), Positives = 558/867 (65%), Gaps = 50/867 (5%)

Query  5    YRPQDIEQKVQEHWDNNKTFVVNEDPNKEKFYCLSMFPYPSGR-LHMGHVRNYTIGDVVS  63
            Y    IE K Q  W +N TF    D++K KFY L MFPYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRLQGKNVMQPIGWDAFGLPAENAAVKNKTAPAPWTYENIEYMKNQLKLLGFGYDWSR  123
            R++R QG NV++P+GWDAFGLPAE+ A+     PA  T ENI   K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EFATCTPEYYRWEQEFFTKLYNKGLVYKKTSSVNWCPNDQTVLANEQV-EDGCCWRCDTP  182
            E  T  P+YY+W Q +FTKLY+KGL Y    +VNW  +  T +ANE+V  DG   R + P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VEQKKIPQWFIKITEYAQELLDDLDTLDGWPEMVKTMQRNWIGRSEGVELSFAVNGEEAP  242
            V +K + QW +KIT YA+ LL+DL+ +D WPE +K MQRNWIG+S G +++F V++ +  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LEVYTTRPDTLMGVTYVGIAAGHPLAEKAAATNP--ELFAFT-EECRNTKVAEAELATME  299
            + V+TTRPDTL G TY  +A+ H+L +  ++++    +  +  +   ++ +A ++LA  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGMDTGLRAVHPLNGREVPIYVANFVLMDYGTGAVMAVPAHDQRDYEFATKYGLDIIPV  359
            K G+ TG  A++P+NG+E+P+ +A++VL  YGTGA+MAVPAHD+RD EFA ++ LDIIPV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  360  IKPEDGSELNVSEEAYTEKGVLFDSGEFDGLAFQDAFDaiaakleaegkgkkTVNFRLRD  419
            +        NV E A+TE G+ ++S+ +DGL    A+  +   LEAEG G+  V +RLRD
Sbjct  362  LEGG-----NVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMVTTEDGEVHPVPADQLPVILP--ENVVMDGVT-SPIKADKEWAKT  476
            W  SRQRYWG PIP++  EDG   +VP  +LP++LP   ++   G   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  TF-NGEPALRETDTFDTFMESSWYYARYCSPQADDIL-DPEKANYWLPVDQYVGGIEHAC  534
            T  +G  + RET+T      SSWYY RY  P+  + L D E  + WLPVD YVGG EHA 
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  535  MHLLYSRFFHKLLRDAGYVTSNEPFKQLLCQGMVLADAFHHTNEKGTKEWIAPTDVTIER  594
            +HLLY+RF HK+L D G V ++EPF++L+ QGM+L+ +++++  +G+   + +TD    R
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDS--RGA---LVATDKVEKR  591

Query  595  DAK-GRIEKAIDDQGREVQHSGMIKMSKSKNNGIDPQEMVDKFGADTVRLFMMFASPADM  653
            D+   ++E      G E++++   KMSKS +N ++P+++V+++GADT+R++ MF +P D 
Sbjct  592  DGSFFHVET-----GEELEQAP-AKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  654  TLEWQESGVEGASRFLKRVWKLVHEHTNKGTVEALDVAALSGNQKALRRDVHKTIAKVSD  713
            ++ W E G+EG+ +FL RV +L+   T K   E         N  AL +  + T+  V++
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLI---TTKEITEE--------NSGALDKVYNETVKAVTE  694

Query  714  DIGRRQTFNTAIAAIMELMNKLNKAPQESAQDRALLDEALKAVVVMLYPMTPHASFEMWE  773
            ++++ + FNTAIA +M ++N  NK       +  L+ +  K+ V ++ P +PH + E+W+
Sbjct  695  QVDQMK-FNTAIAQLMVFVNAANK-------EDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  774  ALGETD--IDTATWPTFDKNALIEDEKTIVVMINGKLRAKLIVAADATEEQVKELGLKDE  831
            AL  ++  I    WP++D + L+E++  IVV I+GK++AKL+VA D + E+++E++L +E
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  832  NAIKFLDGLTIRKVIYVPGKLLNIVAN  858
            +    + G  I KVI VP KL+NIV +
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVIK  833

1388) LFE_0465 in NC_017094


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  529 bits (1995),  Expect = 4e-151, Method: Compositional matrix adjust.
 Identities = 348/858 (41%), Positives = 542/858 (64%), Gaps = 69/858 (8%)

Query  6    YLFKEIEANVQAIWEESNAFRTENQSDRPKFYCLEMFPYPSGR-IHMGHVRNYSIGDALA  64
            Y    IE++ QA+W ++++F+T  ++ +PKFY L+MFPYPSG  +H+GH   Y+  D L+
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  65   RYKRMRGFNVLHPMGWDAFGLPAENAAIQRNIPPRTWTIDNIAHMKKQLKKLGLSYDWDR  124
            R+KR +G NVLHPMGWDAFGLPAE+ A++    P   T +NIA+ K+Q++ LG+SYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  125  EVATCLPDYYRWNQWLFLQFLKRGLAYKKGGLLNWCDQCATVLANEQV-EEGLCWRCKSP  183
            EV T  P+YY+W QW+F ++  +GLAY     +NW ++ +T +ANE+V  +G   R   P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  184  VELRSLEQWYLKITDYAKELHDTLKELTGWPEKVRTMQENWIGPSTGAHIDFTVAGLKKH  243
            V  +++ QW LKIT YA  L + L E+ +WPE ++ MQ NWIG STGA++ F V +  K+
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  244  LTVFTTRPDTLFGVTFVTIAPeheemeellslsPNRDLAKAFIHETLHKRTTERNAELVE  303
            +TVFTTRPDTLFG T+  +APEH  ++ + +      +A  + +++  K    R     E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVA-DYKRQASLKSDLARTDLAKE  301

Query  304  KEGIDSGVRLVHPLTGETIPLWIGNFVVSGYGTGIVMGVPAHDTRDFEFAKKYGIPIKTV  363
            K G+ +G   ++P+ G  +P+WI+++V+++YGTG +M+VPAHD RD EFAK++ + I  V
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  364  ISDSSNNPLQTQQEAMTGPGILVQSGQFDGLKNDQAKIEITRYLEEKGAGRSVTTYRLRD  423
            + +++      ++ A T  G+ ++S+ +DGL +  A   +   LE  G G    TYRLRD
Sbjct  362  LEGGN-----VEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  424  WGISRQRYWGTPIPVLYCDGCGMVPVPEKDLPVLLP--EHVSFTGKGGSPLAEQPSFLNV  481
            W +SRQRYWG PIP++  ++    +VPE +LP++LP   ++  +G G SPLA+    L+V
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  482  RCPQCGKDAKRETDTMDTFIDSSWYFLRFTDPKNTEMPFDRLKSAHWLPVDQYVGGVEHA  541
               + G  ++RET+TM    +SSWY+LR+ DP NTE   D     +WLPVD YVGG EHA
Sbjct  477  -TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  542  ILHLLYARFFTKVLNDIGLSPVREPFQSLLTQGMVL-------------------KDGS-  581
            +LHLLYARF  KVL D+G+ P +EPFQ L+ QGM+L                   +DGS 
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSF  595

Query  582  --------------KMSKSKGNVVDPDLLIDRYGADTVRLFTLFSAPPDKDLAWDDKAVE  627
                          KMSKS  NVV+PD ++++YGADT+R++ +F +P D  +AW + ++E
Sbjct  596  FHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLE  655

Query  628  GAYRFLGRLFQKSQELLTHPGFQKRASFTDELPSELRLVRTKIHETIQDVTRDLDGDAQM  687
            G+ +FL+R+++    L+T         +T+E ++ L  V    +ET++ VT ++D + + 
Sbjct  656  GSRKFLDRVYR----LIT------TKEITEENSGALDKV---YNETVKAVTEQVD-QMKF  701

Query  688  NTAIARLMELLNTLYSVDIQNGAAERSVLHEGLHVTSMLLSPFAPHLSQHLWSSLGEEGL  747
            NTAIA+LM ++N+    D   +   ++ ++        L++PFAPHL+++LW +L   G 
Sbjct  702  NTAIAQLMVFVNAANKEDKLFSDYAKGFVQ--------LIAPFAPHLGEELWQALTASGE  753

Query  748  VLN-AGWPKIDQSALLRDVVPFIVQVNGKLRATLMLPPATTEAELKEQALQDEKVTRVLE  806
             ++   WP  D+S L+ + V ++VQ++GK++A L+++   +  EL+E AL +EKV   + 
Sbjct  754  SISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIA  813

Query  807  GLQIRKIVHVPGKLLNFV  824
            G +I K++ VP KL+N+V
Sbjct  814  GKDIIKVIAVPNKLVNIV  831

1389) Selsp_0877 in NC_015437


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  528 bits (1994),  Expect = 5e-151, Method: Compositional matrix adjust.
 Identities = 359/842 (43%), Positives = 537/842 (64%), Gaps = 69/842 (8%)

Query  22   VYKTEIDRTQPEYYVLEMFPYPSG-NLHMGHVRNYSIGDVIARFKKMQGCNVLHPMGFDA  80
             +KT  D ++P +Y L+MFPYPSG  LH+GH   Y+  D+++RFK+ QG NVLHPMG DA
Sbjct  22   TFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSRFKRAQGHNVLHPMGWDA  81

Query  81   FGMPAENAAIKHGVKPADWTYSNIENMKRQQMSMGLSYDWSREAVTCRPEYYRWTQWLFE  140
            FG+PAE+ A+  G  PA+ T  NI N KRQ  ++G+SYDW RE  T  P+YY+WTQW+F 
Sbjct  82   FGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFT  141

Query  141  LFYKKGLAYKKEASVNWCDTCGTVLANEQVI-DGKCWRCDSEVHKKDLSQWFLKITdyad  199
             +Y KGLAY  E +VNW +  GT +ANE+V+ DG   R +  V +K + QW LKIT    
Sbjct  142  KLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKIT-AYA  200

Query  200  elladldklkGWPERVKTMQENWIGRSEGLEFDIDVPALGEKIAVYTTRADTAYGVTFVA  259
            E L +     +WPE +K MQ NWIG+S G +  + V   +  ++V+TTR+DT +G T+  
Sbjct  201  ERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAV  260

Query  260  LAAEHPLMEKILADNPKAEELRAFADKVKAQSELERTSGESEKEGMFTGLYAVNPFNGRK  319
            LA+EH+L++ I + + +AE +  +  +   +S+L RT    EK G+ TG YA+NP NG+ 
Sbjct  261  LAPEHALVDAITTSD-QAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAINPVNGKE  319

Query  320  VELWVTNYVLAEYGTGAVMGVPSEDQRDWMFAKKYDLPIIVTLRPKDRELKLEEMTEAYT  379
            + +W+++YVLA YGTGA+M+VP++D+RDW FAK+++L II  L   + E        A+T
Sbjct  320  MPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVE------EAAFT  373

Query  380  AKDGILVNSAEFDGMEMHEALAAIVEKAVKEGFGRRKVNYRLRDWLISRQRYWGAPIPVI  439
              DG+ +NS  +DG++   A+A +VE    EG G  +V YRLRDWL+SRQRYWG PIP+I
Sbjct  374  E-DGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPII  432

Query  440  YCDKCGeqlvpeeelpvklpedvNFEQGTV--SPLAQSESFVHCTCPQCGGPARRETDTM  497
              +      VPE ELP+ LP   ++  +    SPLA+    ++ T  + G  +RRET+TM
Sbjct  433  HWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED-GVKGRRETNTM  491

Query  498  DTFICSSWYYMRYTDPHNTHKPFAADKVNYWAPVDQYIGGIEHAILHLLYSRFFTKVLRD  557
                 SSWYY+RY DPHNT+K    + ++ W PVD Y+GG EHA+LHLLY+RF  KVL D
Sbjct  492  PQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYD  551

Query  558  EKLLDFDEPFQNLLTQGMVI-------------------KDG---------------AKM  583
              ++   EPFQ+L+ QGM++                   +DG               AKM
Sbjct  552  LGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEELEQAPAKM  611

Query  584  SKSKGNVVSPEEIIQKYGADTARLFILFAAPVERDLEWSDQGVEGAFRFLNRVWRIVAHF  643
            SKS  NVV+P++++++YGADT R++ +F +P++  + WS++G+EG+ +FL+RV R++   
Sbjct  612  SKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLI---  668

Query  644  EDAIREGIDDYDHSTLTAEEKSLRRTLHQTIKKVTEDVGERFMFNTAISAVMELVNAFYA  703
              + +E  ++        +  +L +  ++T+K VTE+V ++  FNTAI+ +M +VNA   
Sbjct  669  --TTKEITEE--------NSGALDKVYNETVKAVTEQV-DQMKFNTAIAQLMVFVNA---  714

Query  704  FQEKTVHPGLVREISFALVKMLAPFAPHITEELWSRMEGKG-SVHDARWPKFDRAAIVED  762
                  +  L  + + ++V+++APFAPH+ EELW  + + G S+    WP +D + +VE+
Sbjct  715  ---ANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVEN  771

Query  763  EVEIVLQINGKVRDKLTVPADMEPQEMEKLALAQPKVVELTAGKTVVKVICVPKKLVNIV  822
            +VEIV+QI+GKV+ KL V+ D+  +E++ +ALA+ KV    AGK ++KVI VP+KLVNIV
Sbjct  772  DVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIV  831

Query  823  VK  824
            +K
Sbjct  832  IK  833

1390) leuS in NC_016807


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  528 bits (1991),  Expect = 7e-151, Method: Compositional matrix adjust.
 Identities = 340/846 (41%), Positives = 539/846 (64%), Gaps = 72/846 (8%)

Query  2    YNHNLLEEKWLQLWKTKQVNRFFDDKTKPKYYILDMFPYPSAAGLHLGHVRAYTITDVLS  61
            Y+H  +E KW  +W  ++  +   D +KPK+Y LDMFPYPS+AGLH+GH  +YT TD+LS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  62   RYHKAKGFNVIHPIGFDAFGLPAEQYAIASNKHPGDWTDKNITNFIEQLTAFGFDYDYQL  121
            R+ +A+G NV+HP+G DAFGLPAEQYA+ + ++P++ T  NI+NF  Q+ A+GF YD + 
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  122  SLKTTDPRYYQYTQWIFGQLFEAGLAEVKEIDVNWCAELGTVLANEEVLIDSNGNAVSER  181
             ++TTDP YY+ TQWIF +L+E GLA   E+ VNW  ELGT +ANEEVL D+     SER
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGT----SER  179

Query  182  GEFPVTKRKMKQWVLKITAFAESLLNGLAELDWHQSIKEMQTNWIGKSEGVEVTFDIENS  241
            G +PV ++ M+QW+LKITA+AE LL++L E+DW +SIK+MQ NWIGKS G +VTF + ++
Sbjct  180  GGYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDT  239

Query  242  KETITIFTTKVQTIFGVTFLALSTSHPLVKEVAKTNPK--IAQFLqkqaqktttvkqPET  299
               +T+FTT+ +T+FG T+  L+  H+LV  ++ ++    +A++ ++QA   + + + + 
Sbjct  240  DKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADY-KRQASLKSDLARTDL  298

Query  300  LHDGVDLKLK--AINPATNTAIPLYVANYVVEGYGTDAVMGVPAHNENDNFFARKQKLPI  357
              +  ++     AINP     +P+ +A+YV+ +YGT+A+M+VPAH+E D  FA++ +L I
Sbjct  299  AKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDI  358

Query  358  ITVID---------KQERLQHSGQF-SGLNSQTANTQITQMLVERQKAKKTTVYKLRDWI  407
            I V++          ++ L+ +++F  GL+  +A +++ + L     ++    Y+LRDW+
Sbjct  359  IPVLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWL  418

Query  408  FSRQRYWGEPFPILFDENNQPHLV--KELPVTLPALANYQPDGSTNPPLWRNQEWAKV-K  464
            FSRQRYWGEP+PI+  E+  +  V   ELP+ LP   + +P G+ ++PL    +W  V +
Sbjct  419  FSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTR  478

Query  465  QGNQTFTRETSTMPQWAGSCWYYLGYLMLINNENFWPIDSKEAKDLFERYLPVDLYVGGA  524
            ++     RET+TMPQWAGS WYYL Y+   N E++         +L+ + LPVD+YVGGA
Sbjct  479  EDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKL------ADEELLKQWLPVDIYVGGA  532

Query  525  EHAVLHLLYARFWHQFLYQKGIVTTKEPFKKLINQGMVLGPD------------------  566
            EHAVLHLLYARFWH+ LY+ G+V TKEPF+KL+NQGM+LG                    
Sbjct  533  EHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRD  592

Query  567  ---------------GKKMSKSKGNTINPTPLIDSHGADALRLYLMFMGPISAALTWLDD  611
                             KMSKS  N +NP  +++  GAD+LR+Y MFMGP+ A+++W ++
Sbjct  593  GSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEE  652

Query  612  GLNGMRRWLDRVHNFFHKENIIKETVDQ-ETVYGYNLFLKRSYEHLEKQELNLVISQMMI  670
            GL+G R+ LDRV  ++   +I  E  +  + VY     +K   E++++  +N  I+Q+M+
Sbjct  653  GLEGSRKFLDRVYRLITTKEITEENSGALDKVYNET--VKAVTEQVDQMKFNTAIAQLMV  710

Query  671  FLNLLYKTKQLTLAYAKGFLTVLSFFAPYLAEELNAKL-GMEPFIVHAQLPNVDNSVLET  729
            F+N   K  +L   YAKGF+ +++ FAP L+EEL   L +    I     P+ D+S L  
Sbjct  711  FVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVE  770

Query  730  DKVKIILSVNGRFKG----TKEFAKGVDEQTVLKAFKTDPEFQALFDQPLARVVFVPNRI  785
            + V I++ ++G+ K+    +K++++   ++  L   K ++E+ +   + + +V+ VPN++
Sbjct  771  NDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAG---KDIIKVIAVPNKL  827

Query  786  INVLLK  791
            +N+++K
Sbjct  828  VNIVIK  833

1391) leuS in NC_017504


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  528 bits (1991),  Expect = 7e-151, Method: Compositional matrix adjust.
 Identities = 340/846 (41%), Positives = 539/846 (64%), Gaps = 72/846 (8%)

Query  2    YNHNLLEEKWLQLWKTKQVNRFFDDKTKPKYYILDMFPYPSAAGLHLGHVRAYTITDVLS  61
            Y+H  +E KW  +W  ++  +   D +KPK+Y LDMFPYPS+AGLH+GH  +YT TD+LS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  62   RYHKAKGFNVIHPIGFDAFGLPAEQYAIASNKHPGDWTDKNITNFIEQLTAFGFDYDYQL  121
            R+ +A+G NV+HP+G DAFGLPAEQYA+ + ++P++ T  NI+NF  Q+ A+GF YD + 
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  122  SLKTTDPRYYQYTQWIFGQLFEAGLAEVKEIDVNWCAELGTVLANEEVLIDSNGNAVSER  181
             ++TTDP YY+ TQWIF +L+E GLA   E+ VNW  ELGT +ANEEVL D+     SER
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGT----SER  179

Query  182  GEFPVTKRKMKQWVLKITAFAESLLNGLAELDWHQSIKEMQTNWIGKSEGVEVTFDIENS  241
            G +PV ++ M+QW+LKITA+AE LL++L E+DW +SIK+MQ NWIGKS G +VTF + ++
Sbjct  180  GGYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDT  239

Query  242  KETITIFTTKVQTIFGVTFLALSTSHPLVKEVAKTNPK--IAQFLqkqaqktttvkqPET  299
               +T+FTT+ +T+FG T+  L+  H+LV  ++ ++    +A++ ++QA   + + + + 
Sbjct  240  DKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADY-KRQASLKSDLARTDL  298

Query  300  LHDGVDLKLK--AINPATNTAIPLYVANYVVEGYGTDAVMGVPAHNENDNFFARKQKLPI  357
              +  ++     AINP     +P+ +A+YV+ +YGT+A+M+VPAH+E D  FA++ +L I
Sbjct  299  AKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDI  358

Query  358  ITVID---------KQERLQHSGQF-SGLNSQTANTQITQMLVERQKAKKTTVYKLRDWI  407
            I V++          ++ L+ +++F  GL+  +A +++ + L     ++    Y+LRDW+
Sbjct  359  IPVLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWL  418

Query  408  FSRQRYWGEPFPILFDENNQPHLV--KELPVTLPALANYQPDGSTNPPLWRNQEWAKV-K  464
            FSRQRYWGEP+PI+  E+  +  V   ELP+ LP   + +P G+ ++PL    +W  V +
Sbjct  419  FSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTR  478

Query  465  QGNQTFTRETSTMPQWAGSCWYYLGYLMLINNENFWPIDSKEAKDLFERYLPVDLYVGGA  524
            ++     RET+TMPQWAGS WYYL Y+   N E++         +L+ + LPVD+YVGGA
Sbjct  479  EDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKL------ADEELLKQWLPVDIYVGGA  532

Query  525  EHAVLHLLYARFWHQFLYQKGIVTTKEPFKKLINQGMVLGPD------------------  566
            EHAVLHLLYARFWH+ LY+ G+V TKEPF+KL+NQGM+LG                    
Sbjct  533  EHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRD  592

Query  567  ---------------GKKMSKSKGNTINPTPLIDSHGADALRLYLMFMGPISAALTWLDD  611
                             KMSKS  N +NP  +++  GAD+LR+Y MFMGP+ A+++W ++
Sbjct  593  GSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEE  652

Query  612  GLNGMRRWLDRVHNFFHKENIIKETVDQ-ETVYGYNLFLKRSYEHLEKQELNLVISQMMI  670
            GL+G R+ LDRV  ++   +I  E  +  + VY     +K   E++++  +N  I+Q+M+
Sbjct  653  GLEGSRKFLDRVYRLITTKEITEENSGALDKVYNET--VKAVTEQVDQMKFNTAIAQLMV  710

Query  671  FLNLLYKTKQLTLAYAKGFLTVLSFFAPYLAEELNAKL-GMEPFIVHAQLPNVDNSVLET  729
            F+N   K  +L   YAKGF+ +++ FAP L+EEL   L +    I     P+ D+S L  
Sbjct  711  FVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVE  770

Query  730  DKVKIILSVNGRFKG----TKEFAKGVDEQTVLKAFKTDPEFQALFDQPLARVVFVPNRI  785
            + V I++ ++G+ K+    +K++++   ++  L   K ++E+ +   + + +V+ VPN++
Sbjct  771  NDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAG---KDIIKVIAVPNKL  827

Query  786  INVLLK  791
            +N+++K
Sbjct  828  VNIVIK  833

1392) leuS in NC_009092


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  528 bits (1991),  Expect = 8e-151, Method: Compositional matrix adjust.
 Identities = 361/870 (42%), Positives = 554/870 (64%), Gaps = 51/870 (5%)

Query  5    YLPSEIEAKVQQHWQDTKTFEVTEDESKEKFYCLSMFPYPSGR-LHMGHVRNYTIGDVVA  63
            Y  + IE+K Q  W D  TF    D SK KFY L MFPYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRLQGKNVLQPIGWDSFGLPAENAAINNKTAPAPWTYENIDYMKNQLKMLGFGYDWSR  123
            R++R QG NVL+P+GWD+FGLPAE+ A++    PA  T ENI   K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EIATCTPEYYRWEQWFFTKLYEKGLVYKKTASVNWCPNDETVLANEQV-QDGCCWRCDTQ  182
            E+ T  P+YY+W QW+FTKLYEKGL Y    +VNW  +  T +ANE+V  DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VVQKEIPQWFIKITDYAEELLNDIDQLDEWPEQVKTMQRNWIGRSEGIEMTFQVEGSDQS  242
            VV+K + QW +KIT YAE LL+D++++D WPE +K MQRNWIG+S G ++TF+V ++D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  FDIYTTRPDTVMGVTYVAIAAGHPLAQQ--AAENNPVLAEFIEECKNADtteaamaamek  300
            F ++TTRPDT+ G TY  +A+ H+L +   ++++   +A++  +         +  A EK
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEK  302

Query  301  kGVDTGLKAIHPLTGKLVPIWAANFVLMNYGTGAVMSVPGHDQRDYEFATKYGLPIVGVI  360
             GV TG  AI+P+ GK +P+W A++VL +YGTGA+M+VP+HD+RD EFA ++ L I+ V+
Sbjct  303  TGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL  362

Query  361  KPADGELDISEEAYTEKGILFNSGDSFPELDGLDFQAAFDAIDAKLSSEGKGKRQVNYRL  420
              +    ++ E A+TE G+ +NS+  F  LDGLD  +A+  +   L +EG G+ +V YRL
Sbjct  363  EGG----NVEEAAFTEDGLHINSD--F--LDGLDKASAIAKMVEWLEAEGVGNENVTYRL  414

Query  421  RDWGVSRQRYWGAPIPMVTLADGTVMPTPEDQLPVILP--EDVVMDGI-QSPIKADKEWA  477
            RDW  SRQRYWG PIP++   DGT  + PE +LP++LP   D+   G  +SP+    +W 
Sbjct  415  RDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWL  474

Query  478  K-TQVNGQEAFRETDTFDTFMESSWYYARYCSPKADQML-DPAKANYWLPVDQYIGGIEH  535
              T+ +G  + RET+T      SSWYY RY  P   + L D    + WLPVD Y+GG EH
Sbjct  475  EVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEH  534

Query  536  ACMHLLYFRFFHKLLRDIGLVNSDEPAKRLLTQGMVLADAFYYTDDKGARVWVSPNDAKV  595
            A +HLLY RF HK+L D+G+V + EP ++L+ QGM+L+ +  Y D +GA V       KV
Sbjct  535  AVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS--YRDSRGALV----ATDKV  588

Query  596  TETDDKGRIVKAVDSQGHELVYTGMSKMSKSKNNGIDPQEMVDKYGADTVRLFMMFASPP  655
               D+    V + +   +     + +KMSKS +N ++P+++V++YGADT+R++ MF +P 
Sbjct  589  EKRDGSFFHVETGEELEQ-----APAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPL  643

Query  656  ELTLEWQESSVEGAHRFIKRLWKL-AHDHVSQGPTVALNVASLDSAQKELRRELHKTIAK  714
            + ++ W E ++EG+++F+ R+ +L +  ++++  + AL+            +  + T+  
Sbjct  644  DASIAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALD------------KVYNETVKA  691

Query  715  VGDDIERRQMFNTAIASVMELMNRLQKAPMESEQDRALMQEALCAVVRLLYPIIPHTSFE  774
            V +++++ + FNTAIA +M ++N        ++++  L  +   + V+L+ P+ PH + E
Sbjct  692  VTEQVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEE  743

Query  775  LWQAL-GHEETIENVLWPVVDESALVEDSKLIIVQVNGKLRakvtvaadadkdtveaaGM  833
            LWQAL +  E+I  V WP  DES LVE+   I+VQ++GK++AK+ VA D  ++ ++  ++
Sbjct  744  LWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVAL  803

Query  834  AEEGVIKHTEGKTVRKVIYVPGKLLNIVAN  863
            A+E V  +  GK + KVI VP KL+NIV +
Sbjct  804  ANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

1393) TOPB45_1433 in NC_015682


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  527 bits (1988),  Expect = 1e-150, Method: Compositional matrix adjust.
 Identities = 358/866 (42%), Positives = 546/866 (64%), Gaps = 45/866 (5%)

Query  4    YDFSSIEAKWQKLWEENKIFEVKRDPSKPKYYVLEMFPYPSGR-IHMGHVRNYTLGDILA  62
            YD ++IE+KWQ +W +N  F    D+SKPK+Y L+MFPYPSG  +H+GH   YT  DIL+
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RVKRMKGYNVLHPMGWDAFGLPAENAALKHGVHPAKWTYSNIDYMRNQLKKLGFSYDWSR  122
            R KR +G NVLHPMGWDAFGLPAE+ A+  G +PA  T  NI   + Q++ LGFSYDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EFATCDPEYYKHEQRFFIEMYERGLAYRKKTLVNWCPSCHTVLANEQV-ENGACWRCGEE  181
            E  T DP+YYK  Q++F  +YE+GLAY     VNW     T +ANE+V  +G+  R G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VTLKEMEGWFLKITAYAeelledlkkleGHWPEKVITMQINWIGKSEGAEIKFPIPEIEE  241
            V  K M  W LKITAYAE LLEDL  +  +WPE +  MQ NWIGKS GA++ F + + + 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV--DWPESIKDMQRNWIGKSTGANVTFKVKDTDK  241

Query  242  DLIVYTTRPDTLFGATFVCMSPEHPMakkiaekkglkkeleNFIEKVRKERRDIEAGIA-  300
            D+ V+TTRPDTLFGAT+  ++PEH++   I+          ++  +         +++A 
Sbjct  242  DFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVA-DYKRQASLKSDLARTDLAK  300

Query  301  EKEGLFLETYAFHPLTAEKLPLFVANFVLMEYGTGAIMCVPAHDQRDFEFAKKYKLPIKV  360
            EK G+   +YA++P+ +  +P+ +A++VL  YGTGAIM VPAHD+RD EFAK+++L I  
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  361  VIKPKDKDLVPEEMESAYEEPGIMVNSDIFTGLDSIEGKAKITAYLEEKGLGKKKVTYRL  420
            V+   + +      E+A+ E G+ +NSD++ GLD   + AK+   LE  G+G+ +VTYRL
Sbjct  361  VLEGGNVE------EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRL  414

Query  421  RDWGISRQRYWGCPIPMIYCERCGIVPEKIENLPVILPLDAQIDPSGR--SPLPNLSEFV  478
            RDW +SRQRYWG PIP+I  E     +    +LP++LP+  +I PSG   SPL+N+++ +
Sbjct  415  RDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWL  474

Query  479  NTKCPKCGSQAKRETDTFDTFVESSWYFARFACPNYPEPFNKEDI-KYWLPVDQYIGGIE  537
            +      G +++RET+T      SSWY+ R+  P+  E +  E++ K WLPVD Y+GG E
Sbjct  475  EVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAE  533

Query  538  HAILHLLYARFFTKVLRDLGYFDLDEPFLNLLTQGMVIKETYKCPIHGWLYPEEVS-PEG  596
            HA+LHLLYARF  KVL DLG     EPF +L+ QGM++  +Y+ +  + +  + V   +G
Sbjct  534  HAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDG  593

Query  597  KCLKDGCGKEVIVGKFEKMSKSKCNIVDPDQMIEKYGADTVRLFIAFAAPPEKDLEWSDH  656
              +    G E+  +   KMSKS  N+V+PD+++E+YGADT+R++  F +P +  + WS++
Sbjct  594  SFFHVETGEELEQAP-AKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEE  652

Query  657  GIEGAFRFLKRLYNLVINYAEKLKEVSYKEEdlkdlpnnllklrrklHQTIKKVSEDLEK  716
            G+EG+ +FL R+Y L+       KE++          +N   L +  ++T+K V+E+++ 
Sbjct  653  GLEGSRKFLDRVYRLITT-----KEIT---------EENSGALDKVYNETVKAVTEQVD-  697

Query  717  RLHFNTAIAAIMEFLNLLEDTLKEISTEDEKNKKVLKECFDKVLLLISPICPHIAEELWE  776
            ++ FNTAIA +M F+N             +K+ K++ +     + LI+P+ PH++EELW+
Sbjct  698  QMKFNTAIAQLMVFVN-----------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  777  ELGHKT-FISLEKFPEYDPALIEEDIFILVIQVNGKVRDQIEVPVELSKEEIIRLAQERP  835
             L      IS    P YD + + E+   +V+Q++GKV+ ++ V+ +LS+EE+  +A    
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  836  KIKKYLEGKNLKNVVFVPKKLVNFVV  861
            K++  + GK++ +V+ VP+KLVN+V+
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVI  832

1394) leuS in NC_000912


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  527 bits (1990),  Expect = 1e-150, Method: Compositional matrix adjust.
 Identities = 340/846 (41%), Positives = 539/846 (64%), Gaps = 72/846 (8%)

Query  2    YNHNLLEEKWLQLWKTKQVNRFFDDKTKPKYYILDMFPYPSAAGLHLGHVRAYTITDVLS  61
            Y+H  +E KW  +W  ++  +   D +KPK+Y LDMFPYPS+AGLH+GH  +YT TD+LS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  62   RYHKAKGFNVIHPIGFDAFGLPAEQYAIASNKHPGDWTDKNITNFIEQLTAFGFDYDYQL  121
            R+ +A+G NV+HP+G DAFGLPAEQYA+ + ++P++ T  NI+NF  Q+ A+GF YD + 
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  122  SLKTTDPRYYQYTQWIFGQLFEAGLAEVKEIDVNWCAELGTVLANEEVLIDSNGNAVSER  181
             ++TTDP YY+ TQWIF +L+E GLA   E+ VNW  ELGT +ANEEVL D+     SER
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGT----SER  179

Query  182  GEFPVTKRKMKQWVLKITAFAESLLNGLAELDWHQSIKEMQTNWIGKSEGVEVTFDIENS  241
            G +PV ++ M+QW+LKITA+AE LL++L E+DW +SIK+MQ NWIGKS G +VTF + ++
Sbjct  180  GGYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDT  239

Query  242  KETITIFTTKVQTIFGVTFLALSNSHPLVKEVAKTNPK--IAQFLqkqaqktttvkqPET  299
               +T+FTT+ +T+FG T+  L+  H+LV  ++ ++    +A++ ++QA   + + + + 
Sbjct  240  DKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADY-KRQASLKSDLARTDL  298

Query  300  LHDGVDLKLK--AINPATNTAIPLYVANYVVEGYGTDAVMGVPAHNENDNFFARKQKLPI  357
              +  ++     AINP     +P+ +A+YV+ +YGT+A+M+VPAH+E D  FA++ +L I
Sbjct  299  AKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDI  358

Query  358  ITVID---------KQERLQHSGQF-SGLNSQTANTQITQMLVERQKAKKTTVYKLRDWI  407
            I V++          ++ L+ +++F  GL+  +A +++ + L     ++    Y+LRDW+
Sbjct  359  IPVLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWL  418

Query  408  FSRQRYWGEPFPILFDENNQPHLV--KELPVTLPALANYQPDGSTNPPLWRNQEWAKV-K  464
            FSRQRYWGEP+PI+  E+  +  V   ELP+ LP   + +P G+ ++PL    +W  V +
Sbjct  419  FSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTR  478

Query  465  QGNQTFTRETSTMPQWAGSCWYYLGYLMLINNENFWPIDSREAKDLFERYLPVDLYVGGA  524
            ++     RET+TMPQWAGS WYYL Y+   N E++         +L+ + LPVD+YVGGA
Sbjct  479  EDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKL------ADEELLKQWLPVDIYVGGA  532

Query  525  EHAVLHLLYARFWHQFLYQKGIVTTKEPFKKLINQGMVLGPD------------------  566
            EHAVLHLLYARFWH+ LY+ G+V TKEPF+KL+NQGM+LG                    
Sbjct  533  EHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRD  592

Query  567  ---------------GKKMSKSKGNTINPTPLIDSHGADALRLYLMFMGPISAALTWLDD  611
                             KMSKS  N +NP  +++  GAD+LR+Y MFMGP+ A+++W ++
Sbjct  593  GSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEE  652

Query  612  GLNGMRRWLDRVHNFFHKENIIKETVDQ-ETVYGYNLFLKRSFEHLEKQELNLVISQMMI  670
            GL+G R+ LDRV  ++   +I  E  +  + VY     +K   E++++  +N  I+Q+M+
Sbjct  653  GLEGSRKFLDRVYRLITTKEITEENSGALDKVYNET--VKAVTEQVDQMKFNTAIAQLMV  710

Query  671  FLNLLYKTKQLTLAYAKGFLTVLSFFAPYLAEELNAKL-GMEPFIVHAQLPNVDNSVLET  729
            F+N   K  +L   YAKGF+ +++ FAP L+EEL   L +    I     P+ D+S L  
Sbjct  711  FVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVE  770

Query  730  DKVKIILSVNGRFKG----TKEFAKGVDEQTVLKAFKTDPEFQALFDQPLARVVFVPNRI  785
            + V I++ ++G+ K+    +K++++   ++  L   K ++E+ +   + + +V+ VPN++
Sbjct  771  NDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAG---KDIIKVIAVPNKL  827

Query  786  INVLLK  791
            +N+++K
Sbjct  828  VNIVIK  833

1395) leuS in NC_014012


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  527 bits (1988),  Expect = 1e-150, Method: Compositional matrix adjust.
 Identities = 355/870 (41%), Positives = 552/870 (64%), Gaps = 51/870 (5%)

Query  6    YQPSEIEAKVQKHWQDEKTFEVTEDENKEKFYCLAMFPYPSGR-LHMGHVRNYTIGDVIA  64
            Y+ + IE+K Q  W D+ TF    D +K KFY L MFPYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  65   RYQRLQGKNVLQPIGWDSFGLPAENAAIKNNTAPAPWTYENIDYMKNQLKMLGFGYDWSR  124
            R++R QG NVL+P+GWD+FGLPAE+ A+     PA  T ENI   K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  125  EIATCTPEYYRWEQWFFTKLFEKGLVYKKTSSVNWCPNDETVLANEQVI-DGCCWRCDTV  183
            E+ T  P+YY+W QW+FTKL+EKGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  184  VEQKEIPQWFIKITEYAdelltdldqldeWPEQVKTMQRNWIGRSEGIEMTFKVVDSEES  243
            V +K + QW +KIT YA E L +  +  +WPE +K MQRNWIG+S G ++TFKV D++  
Sbjct  184  VVRKPMRQWMLKITAYA-ERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  244  FDIYTTRPDTVMGVTYVAIAAGHPLAAQAAVNNP--ELAAFIEECKNADtteaamaamek  301
            F ++TTRPDT+ G TY  +A+ H+L    + ++    +A +  +         +  A EK
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEK  302

Query  302  kGVATGLYATHPLTGKQVPIWAANFVLMNYGTGAVMSVPAHDQRDYEFAIKYGLAIEGVI  361
             GV TG YA +P+ GK++P+W A++VL +YGTGA+M+VPAHD+RD EFA ++ L I  V+
Sbjct  303  TGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL  362

Query  362  KPSDSELDISEVAYTEKGIVFNSGDAFPELDGLDFQGAFDAIDTRLTAEGKGKRQVNFRL  421
              +    ++ E A+TE G+ +NS+  F  LDGLD  +A+  +  +L AEG G+ +V +RL
Sbjct  363  EGG----NVEEAAFTEDGLHINSD--F--LDGLDKASAIAKMVEWLEAEGVGNENVTYRL  414

Query  422  RDWGVSRQRYWGAPIPMMTLADGTVVATPEDQLPVILP--EDVVMDGI-QSPIKADKEWA  478
            RDW  SRQRYWG PIP++   DGT  A PE +LP++LP   D+   G  +SP+    +W 
Sbjct  415  RDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWL  474

Query  479  KTTY-KGEEAFKETDTFDTFMESSWYYARYCSPHADQML-DPAKANYWLPVDQYIGGIEH  536
              T   G  + +ET+T      SSWYY RY  PH  + L D    + WLPVD Y+GG EH
Sbjct  475  EVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEH  534

Query  537  ACMHLLYFRFFHKLLRDIGLVDSDEPAKRLLTQGMVLADAFYYNNERGARVWVAPSDVTV  596
            A +HLLY RF HK+L D+G+V + EP ++L+ QGM+L+ +  Y + RGA        V+ 
Sbjct  535  AVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS--YRDSRGAL-------VAT  585

Query  597  QETDDKGRILKAIDKDGNELVYTGMSKMSKSKNNGIDPQEMVDKFGADTVRLFMMFAAPP  656
            +  + ++  +  ++  G+EL   + +KMSKS +N ++P+++V+++GADT+R++ MF +P 
Sbjct  586  DKVEKRDGSFFHVET-GEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPL  643

Query  657  ELTLEWQESSVEGAHRFIKRLWKL-AHDHIAKGPTAELDIKSLDAKQKELRRELHKTIVK  715
            + ++ W E ++EG+++F+ R+ +L +  +I+   ++ LD            +  + T+  
Sbjct  644  DASIAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALD------------KVYNETVKA  691

Query  716  VTDDIERRQMFNTAIASIMELMNRLLKAPQESEQDRALLNEALSAVVRLLYPIIPHTSFS  775
            VT+++++ + FNTAIA +M ++N        ++++  L+++   + V+L+ P+ PH +  
Sbjct  692  VTEQVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEE  743

Query  776  LWNEL-GNPEAIEDVLWPKADESALVEDRKLIIVQVNGKLRAKITVPADATKEAVEEQGL  834
            LW+ L ++ E+I  V WP  DES LVE+   I+VQ++GK++AK+ V+ D ++E ++E +L
Sbjct  744  LWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVAL  803

Query  835  AEEGVLKHTEGKTIRKIIYIQGKLLNIVAN  864
            A+E V  +  GK I K+I +  KL+NIV +
Sbjct  804  ANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

1396) leuS in NC_010322


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  527 bits (1987),  Expect = 2e-150, Method: Compositional matrix adjust.
 Identities = 363/884 (42%), Positives = 551/884 (63%), Gaps = 74/884 (8%)

Query  5    YTPRDIEAAAQKFWDEQQSFAVTEQPGKDTYYCLSMFPYPSGK-LHMGHVRNYTIGDVIA  63
            Y    IE+  Q FW ++++F    +++K  +Y L MFPYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPMGWDAFGMPAENAAMKNNVAPAKWTYENIDYMKTQLKSLGLAIDWAR  123
            R++R  G NVL+PMGWDAFG+PAE+ AM     PA  T ENI   K Q+++LG++ DW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVTTCKPDYYRWEQWLFTRLFEKGIIYRKNGTVNWDPADQTVLANEQVI-DGRGWRSGAL  182
            EV T  P+YY+W QW+FT+L+EKG+ Y  +  VNW     T +ANE+V+ DG + R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  IEKREIPMYYFRITDYADELLESLDELPGWPEQVKTMQRNWIGKSRGMEVQFPYDQASIG  242
            + ++ +    ++IT YA+ LLE L+E+ +WPE +K MQRNWIGKS G +V F   ++   
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDT---  239

Query  243  HEGTLKVFTTRPDTLMGATYVAVAAEHPLATQAAQGNPALQAFIDECKSGSVAEADMA--  300
             +  + VFTTRPDTL GATY  +A+EH+L    + ++ A    + + K  +   +D+A  
Sbjct  240  -DKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQA--EAVADYKRQASLKSDLART  296

Query  301  --TQEKKGMATSLLVEHPLTGEKLPVWVANYVLMHYGDGAVMAVPAHDERDFEFAHKYNL  358
              ++EK G+ T+    +P+ G  +PVW+A+YVL  YG GA+MAVPAHDERD EFA ++NL
Sbjct  297  DLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNL  356

Query  359  PVKAVVRTSAGDEVGSEWQAAYGEHGQLINSAEFDGLDFAGAFDAIEAALIRKELGKSRT  418
             + +V+  +  +E      AA+ E+G  INS  +DGLD A+A+  +   L    +G+   
Sbjct  357  DIIPVLEGGNVEE------AAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENV  410

Query  419  QFRLRDWGISRQRYWGCPIPIIHCPSCGDVPVPEDQLPVTLP--ENVVPDGAG-SPLARM  475
             +RLRDW +SRQRYWG PIPIIH       +VPE +LP+ LP   ++ P G+G SPLA +
Sbjct  411  TYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANV  470

Query  476  PEFYECTCPKCGTAAKRETDTMDTFVESSWYFARYASPNYDKGLVDPKAANHWLPVDQYI  535
             +  E T    G  ++RET+TM     SSWY+ RY  P+    L D    ++WLPVD Y+
Sbjct  471  TDWLEVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYV  529

Query  536  GGIEHAILHLLYARFFHKLMRDEGLVTSNEPFKNLLTQGMVVAETYYRVASNGGKDWFNP  595
            GG EHA+LHLLYARF HK++ D G+V ++EPF++L+ QGM+++ +Y              
Sbjct  530  GGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY--------------  575

Query  596  ADVEIERDAKAKIIGARL--KTDG--LPVEIG-----GTEKMSKSKNNGVDPQSMIEAYG  646
                  RD+++ ++++    K DG  + VE G     +  KMSKS +N V+P+ ++E YG
Sbjct  576  ------RDSRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYG  629

Query  647  ADTCRLFMMFASPPDMSLEWSDSGVEGASRFLRRVWRLAQA-HVSQGLPGKLDVATLDDA  705
            ADT R++ MF +P D S+ WS+ G+EG+ +FL RV RL  + ++++  +G LD       
Sbjct  630  ADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALD-------  682

Query  706  QKVIRRAIHAAIKQASTDVGQFHKFNTAIAQVMTVMNVLEKAPQATEQDRALLQEGLEAV  765
                 +  + ++K  + +V+Q  KFNTAIAQ+M  +N       A++++  L+ +   + 
Sbjct  683  -----KVYNETVKAVTEQVDQM-KFNTAIAQLMVFVN-------AANKEDKLFSDYAKGF  729

Query  766  TLLLAPITPHISHELWQQLGHAGSVID-AAWPSVDEQALVQDTITLVVQVNGKLRGQVEM  824
              L+AP++PH+++ELWQ L  +G  I   +WPS DE  LV++ + +VVQ++GK+++++ +
Sbjct  730  VQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVV  789

Query  825  PaaasreeveaaarGNENVLRFIDGLTIRKVIVVPGKLVNIVAN  868
            +   SREE++  A +NE+V   I G  I KVI VP KLVNIV +
Sbjct  790  AKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

1397) C985_0387 in NC_020076


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  527 bits (1990),  Expect = 9e-151, Method: Compositional matrix adjust.
 Identities = 340/846 (41%), Positives = 539/846 (64%), Gaps = 72/846 (8%)

Query  2    YNHNLLEEKWLQLWKTKQVNRFFDDKTKPKYYILDMFPYPSAAGLHLGHVRAYTITDVLS  61
            Y+H  +E KW  +W  ++  +   D +KPK+Y LDMFPYPS+AGLH+GH  +YT TD+LS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  62   RYHKAKGFNVIHPIGFDAFGLPAEQYAIASNKHPGDWTDKNITNFIEQLTAFGFDYDYQL  121
            R+ +A+G NV+HP+G DAFGLPAEQYA+ + ++P++ T  NI+NF  Q+ A+GF YD + 
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  122  SLKTTDPRYYQYTQWIFGQLFEAGLAEVKEIDVNWCAELGTVLANEEVLIDSNGNAVSER  181
             ++TTDP YY+ TQWIF +L+E GLA   E+ VNW  ELGT +ANEEVL D+     SER
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGT----SER  179

Query  182  GEFPVTKRKMKQWVLKITAFAESLLNGLAELDWHQSIKEMQTNWIGKSEGVEVTFDIENS  241
            G +PV ++ M+QW+LKITA+AE LL++L E+DW +SIK+MQ NWIGKS G +VTF + ++
Sbjct  180  GGYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDT  239

Query  242  KETITIFTTKVQTIFGVTFLALSNSHPLVKEVAKTNPK--IAQFLqkqaqktttvkqPET  299
               +T+FTT+ +T+FG T+  L+  H+LV  ++ ++    +A++ ++QA   + + + + 
Sbjct  240  DKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADY-KRQASLKSDLARTDL  298

Query  300  LHDGVDLKLK--AINPATNTAIPLYVANYVVEGYGTDAVMGVPAHNENDNFFARKQKLPI  357
              +  ++     AINP     +P+ +A+YV+ +YGT+A+M+VPAH+E D  FA++ +L I
Sbjct  299  AKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDI  358

Query  358  ITVID---------KQERLQHSGQF-SGLNSQTANTQITQMLVERQKAKKTTVYKLRDWI  407
            I V++          ++ L+ +++F  GL+  +A +++ + L     ++    Y+LRDW+
Sbjct  359  IPVLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWL  418

Query  408  FSRQRYWGEPFPILFDENNQPHLV--KELPVTLPALANYQPDGSTNPPLWRNQEWAKV-K  464
            FSRQRYWGEP+PI+  E+  +  V   ELP+ LP   + +P G+ ++PL    +W  V +
Sbjct  419  FSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTR  478

Query  465  QGNQTFTRETSTMPQWAGSCWYYLGYLMLINNENFWPIDSREAKDLFERYLPVDLYVGGA  524
            ++     RET+TMPQWAGS WYYL Y+   N E++         +L+ + LPVD+YVGGA
Sbjct  479  EDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKL------ADEELLKQWLPVDIYVGGA  532

Query  525  EHAVLHLLYARFWHQFLYQKGIVTTKEPFKKLINQGMVLGPD------------------  566
            EHAVLHLLYARFWH+ LY+ G+V TKEPF+KL+NQGM+LG                    
Sbjct  533  EHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRD  592

Query  567  ---------------GKKMSKSKGNTINPTPLIDSHGADALRLYLMFMGPISAALTWLDD  611
                             KMSKS  N +NP  +++  GAD+LR+Y MFMGP+ A+++W ++
Sbjct  593  GSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEE  652

Query  612  GLNGMRRWLDRVHNFFHKENIIKETVDQ-ETVYGYNLFLKRSYEHLEKQELNLVISQMMI  670
            GL+G R+ LDRV  ++   +I  E  +  + VY     +K   E++++  +N  I+Q+M+
Sbjct  653  GLEGSRKFLDRVYRLITTKEITEENSGALDKVYNET--VKAVTEQVDQMKFNTAIAQLMV  710

Query  671  FLNLLYKTKQLTLAYAKGFLTVLSFFAPYLAEELNAKL-GMEPFIVHAQLPNVDNSVLET  729
            F+N   K  +L   YAKGF+ +++ FAP L+EEL   L +    I     P+ D+S L  
Sbjct  711  FVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVE  770

Query  730  DKVKIILSVNGRFKG----TKEFAKGVDEQTVLKAFKTDPEFQALFDQPLARVVFVPNRI  785
            + V I++ ++G+ K+    +K++++   ++  L   K ++E+ +   + + +V+ VPN++
Sbjct  771  NDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAG---KDIIKVIAVPNKL  827

Query  786  INVLLK  791
            +N+++K
Sbjct  828  VNIVIK  833

1398) leuS in NC_008510


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  526 bits (1985),  Expect = 3e-150, Method: Compositional matrix adjust.
 Identities = 345/703 (50%), Positives = 478/703 (68%), Gaps = 56/703 (7%)

Query  199  LVYQAEIPVNWCEALGTVLANEEV--EEWIDKG-YEVVRKPMRQYMMRITAYADRLLEDL  255
            L Y+AE+PVNW E LGT +ANEEV  +   ++G Y VVRKPMRQ M++ITAYA+RLLEDL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  256  KLVQWPSSTLEMQKNWIGKSEGLEITFPFKKPLKSGSDGIRIFTTRPDTIFGVTYMVVAP  315
              V+WP S  +MQ+NWIGKS G ++TF     +K    ++ +FTTRPDT+FG TY V+AP
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFK----VKDTDKDFTVFTTRPDTLFGATYAVLAP  263

Query  316  EHPIVSEITTPEQKQKVEEYQKVSSLKSDLDRMELTKEKTGVFTGSFVLNPANPSKEIPI  375
            EH++V  ITT++Q + V +Y++ +SLKSDL R +L+KEKTGV TGS+ +NP N +KE+P+
Sbjct  264  EHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAINPVN-GKEMPV  322

Query  376  WISDYVLYGYGTGAIMAVPAHDQRDYEFAKTFGLEILPVIEG-EITDVAFDsktsicihs  434
            WI+DYVL +YGTGAIMAVPAHD+RD EFAK F L+I+PV+EG ++ + AF          
Sbjct  323  WIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEAAFTEDGLHINSD  382

Query  435  ssseisiDGLDYSSASSKIISWAESKRIGKKKTQFKLRDWLFARQRYWGEPIPLVHYPSG  494
                   DGLD +SA +K++ W E+  +G+ +  ++LRDWLF+RQRYWGEPIP++H   G
Sbjct  383  FL-----DGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDG  437

Query  495  ITKpipeselplelppnleeFKPSGTGESPLALAKEWLQYKDPETGEIGTRETNTMPQWA  554
             T           + P   +++PSGTGESPLA   +WL+    E G  G RETNTMPQWA
Sbjct  438  -TSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT-REDGVKGRRETNTMPQWA  495

Query  555  GSCWYYLRYIDPKNGKLFCDPDLEKKWMPVDLYVGGAEHAVLHLLYSRFWHKFLYDIGVV  614
            GS WYYLRYIDP N   + D +L K+W+PVD+YVGGAEHAVLHLLY+RFWHK LYD+GVV
Sbjct  496  GSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVV  555

Query  615  STQEPFAKLIHQGLILGE---------------DKR------------------KMSKSL  641
            +T+EPF KL++QG+ILG                +KR                  KMSKSL
Sbjct  556  PTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSL  615

Query  642  GNVINPDDVIRKYGADSLRLFEMFMGPLEMVKPWSTRGVEGVFRFLNRVWRLFHTGEGES  701
             NV+NPDDV+ +YGAD+LR++EMFMGPL+   +WS  G+EG  +FL+RV RL+ T E   
Sbjct  616  KNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKE---  672

Query  702  FRLDEIEPTTEELKILHKTIQKVGEDIPNFSFNTAISQLMIFVNEFTPSDRRPKEVLETF  761
              + E ++ + + K+ + T++ V E++ +  FNTAI+QLM+FVN     D+   +    F
Sbjct  673  --ITEENSGALD-KVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGF  729

Query  762  ILLLAPFAPHIAEELWKR-SGNNKSLSTEKFPEADPQYLVESEILIVVQVNGKLRDEFKA  820
            + L+APFAPH++EELW+  +++  S+S    P  D   LVE+++ IVVQ++GK++  +  
Sbjct  730  VQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVV  789

Query  821  PKDVSEADAISIAKNLDKIKGILDGKTIRKEIYVPGKLINLVI  863
            +KD+S  +   +A   +K+++ + GK I K I VP KL+N+VI
Sbjct  790  AKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832


 Score =  186 bits (689),  Expect = 7e-48, Method: Compositional matrix adjust.
 Identities = 98/142 (70%), Positives = 119/142 (84%), Gaps = 0/142 (0%)

Query  3    YPFQEVESFWQKFWEENKSFQTNIRSSKPKFYCLDMFPYPSGAGLHVGHPEGYTATDILS  62
            Y    +E+ WQ FW +N +F+T   +SKPKFY LDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RFKRMKGFEVLHPMGWDAFGLPAERYAMQTGIHPAITTKNNIDNFRRQIQMIGLSYDWSR  122
            RFKR +G +VLHPMGWDAFGLPAE+YAM+TG +PA  T +NI NF+RQI+ +G+SYDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  ELSTTDPDYYKFTQWIFIQLYQ  144
            E++TTDP+YYK TQWIF +LY+
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYE  145

1399) leuS in NC_008508


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  526 bits (1985),  Expect = 3e-150, Method: Compositional matrix adjust.
 Identities = 345/703 (50%), Positives = 478/703 (68%), Gaps = 56/703 (7%)

Query  199  LVYQAEIPVNWCEALGTVLANEEV--EEWIDKG-YEVVRKPMRQYMMRITAYADRLLEDL  255
            L Y+AE+PVNW E LGT +ANEEV  +   ++G Y VVRKPMRQ M++ITAYA+RLLEDL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  256  KLVQWPSSTLEMQKNWIGKSEGLEITFPFKKPLKSGSDGIRIFTTRPDTIFGVTYMVVAP  315
              V+WP S  +MQ+NWIGKS G ++TF     +K    ++ +FTTRPDT+FG TY V+AP
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFK----VKDTDKDFTVFTTRPDTLFGATYAVLAP  263

Query  316  EHPIVSEITTPEQKQKVEEYQKVSSLKSDLDRMELTKEKTGVFTGSFVLNPANPSKEIPI  375
            EH++V  ITT++Q + V +Y++ +SLKSDL R +L+KEKTGV TGS+ +NP N +KE+P+
Sbjct  264  EHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAINPVN-GKEMPV  322

Query  376  WISDYVLYGYGTGAIMAVPAHDQRDYEFAKTFGLEILPVIEG-EITDVAFDsktsicihs  434
            WI+DYVL +YGTGAIMAVPAHD+RD EFAK F L+I+PV+EG ++ + AF          
Sbjct  323  WIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEAAFTEDGLHINSD  382

Query  435  ssseisiDGLDYSSASSKIISWAESKRIGKKKTQFKLRDWLFARQRYWGEPIPLVHYPSG  494
                   DGLD +SA +K++ W E+  +G+ +  ++LRDWLF+RQRYWGEPIP++H   G
Sbjct  383  FL-----DGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDG  437

Query  495  ITKpipeselplelppnleeFKPSGTGESPLALAKEWLQYKDPETGEIGTRETNTMPQWA  554
             T           + P   +++PSGTGESPLA   +WL+    E G  G RETNTMPQWA
Sbjct  438  -TSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT-REDGVKGRRETNTMPQWA  495

Query  555  GSCWYYLRYIDPKNGKLFCDPDLEKKWMPVDLYVGGAEHAVLHLLYSRFWHKFLYDIGVV  614
            GS WYYLRYIDP N   + D +L K+W+PVD+YVGGAEHAVLHLLY+RFWHK LYD+GVV
Sbjct  496  GSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVV  555

Query  615  STQEPFAKLIHQGLILGE---------------DKR------------------KMSKSL  641
            +T+EPF KL++QG+ILG                +KR                  KMSKSL
Sbjct  556  PTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSL  615

Query  642  GNVINPDDVIRKYGADSLRLFEMFMGPLEMVKPWSTRGVEGVFRFLNRVWRLFHTGEGES  701
             NV+NPDDV+ +YGAD+LR++EMFMGPL+   +WS  G+EG  +FL+RV RL+ T E   
Sbjct  616  KNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKE---  672

Query  702  FRLDEIEPTTEELKILHKTIQKVGEDIPNFSFNTAISQLMIFVNEFTPSDRRPKEVLETF  761
              + E ++ + + K+ + T++ V E++ +  FNTAI+QLM+FVN     D+   +    F
Sbjct  673  --ITEENSGALD-KVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGF  729

Query  762  ILLLAPFAPHIAEELWKR-SGNNKSLSTEKFPEADPQYLVESEILIVVQVNGKLRDEFKA  820
            + L+APFAPH++EELW+  +++  S+S    P  D   LVE+++ IVVQ++GK++  +  
Sbjct  730  VQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVV  789

Query  821  PKDVSEADAISIAKNLDKIKGILDGKTIRKEIYVPGKLINLVI  863
            +KD+S  +   +A   +K+++ + GK I K I VP KL+N+VI
Sbjct  790  AKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832


 Score =  186 bits (689),  Expect = 7e-48, Method: Compositional matrix adjust.
 Identities = 98/142 (70%), Positives = 119/142 (84%), Gaps = 0/142 (0%)

Query  3    YPFQEVESFWQKFWEENKSFQTNIRSSKPKFYCLDMFPYPSGAGLHVGHPEGYTATDILS  62
            Y    +E+ WQ FW +N +F+T   +SKPKFY LDMFPYPSGAGLHVGHPEGYTATDILS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RFKRMKGFEVLHPMGWDAFGLPAERYAMQTGIHPAITTKNNIDNFRRQIQMIGLSYDWSR  122
            RFKR +G +VLHPMGWDAFGLPAE+YAM+TG +PA  T +NI NF+RQI+ +G+SYDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  ELSTTDPDYYKFTQWIFIQLYQ  144
            E++TTDP+YYK TQWIF +LY+
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYE  145

1400) PP1Y_AT802 in NC_015580


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  525 bits (1982),  Expect = 4e-150, Method: Compositional matrix adjust.
 Identities = 345/848 (41%), Positives = 545/848 (65%), Gaps = 34/848 (4%)

Query  5    FDPAQADTRWQAAWDEAQCFKADDTSSKPRSYVLEMFPYPSGR-IHIGHVRNYTMGDVLA  63
            +D +  + +WQA W + + FK++  +SKP+ Y L+MFPYPSG  +H+GH   YT  D+L+
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYKRMTGHEVLHPMGWDAFGMPAENAAMEKGVHPGGWTRENIANMKAQLKRLGFALDWSR  123
            R+KR  GH+VLHPMGWDAFG+PAE+ AM+ G +P+  T ENIAN K Q++ LGF+ DW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EIATCEPEYYGHEQALFLDLYEHGLVYRKESAVNWDPVDQTVLANEQVI-DGRGWRSGAL  182
            E+ T +P+YY   Q +F  LYE GL Y  E +VNW     T +ANE+V+ DG + R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VEKRKLNQWFLKITDFADELLEGLSSLDKWPEKVRTMQENWIGKSQGLQFRFDLSDGGT-  241
            V ++ + QW LKIT +A+ LLE+L  +D WPE ++ MQ NWIGKS G +  F + D +  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  242  VEVYSTRPDTIFGASFVAVAADHPIAQGVAAGNPEVQDFIALCKQGGTTAAELETA----  297
              V++TRPDT+FGA++  +A++H++ +++++++    + +A  K+ ++  ++L  +    
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQA--EAVADYKRQASLKSDLARTDLAK  300

Query  298  EKLGFDTGITARHPFTGAALPVFIANFVLMDYGTGAVMAVPGHDQRDFEFATKYALPIPR  357
            EK G  TG  A +P  G  +PV IA++VL  YGTGA+MAVP+HD+RD EFA ++ L I  
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  358  VVAASLEEADKPFDGEAESGDGVIVNSDFLDGMSVAEAKADVISRAESGGWGEGKTVWRL  417
            V+ ++ +  + +F     + DG+ +NSDFLDG+  A A A ++ + E+ G G+ +   RL
Sbjct  361  VLEGG-NVEEAAF-----TEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRL  414

Query  418  RDWGVSRQRYWGTPIPFIHCEVCGVVPVPKKHLPVTLPEDVDFSTPG---NPLVRHPTWK  474
            RDW  SRQRYWG PIP+IH E     +VP  +LP+ LP   D+  +G   +PL     W 
Sbjct  415  RDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWL  474

Query  475  HVDCPQCGKPARRETDTLDTFVDSSWYFLRF-ASQPGDRPFDPAKIAQWLPVEQYIGGIE  533
            +V   +  K +RRET+T+    +SSWY+LR+  ++  ++  D   + QWLPV+ Y+GG E
Sbjct  475  EVTREDGVK-GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAE  533

Query  534  HAILHLLYARFWTRALARIGKVEVKEPFASLFTQGMVTHETYERRNPENGQPIYFAPGDV  593
            HA+LHLLYARFW + L  +G V  KEPF  LF QGM+   +Y      +++    A + V
Sbjct  534  HAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKV  588

Query  594  ERTAEGATLKADGAPVEIGRVIKMSKSKKNVVDPDEIVATYGADAIRWFMLSDSPPERDL  653
            E+  +G+ +  + +        KMSKS KNVV+PD++V  YGAD++R + +  +P +  +
Sbjct  589  EKR-DGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASI  647

Query  654  PWSEAGIEGCARFVQRLWRLFGQYDASAEGEDKAVDRKAHQTVAAVAQDIESLGFNKAVA  713
            +WSE G+EG  +F++R+ RL+      +E +  A+D+  ++TV AV+++++ + FN A+A
Sbjct  648  AWSEEGLEGSRKFLDRVYRLITT-KEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIA  706

Query  714  RIYELTGVIEKAKPSASRSEAIRKVLLLVAPMMPHLAEE---AFATFGQGLVAEAGWPEV  770
            ++  +  V    K     S+  +  + L+AP  PHL+EE   A+++ G++ ++   WP  
Sbjct  707  QL--MVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGES-ISYVPWPSY  763

Query  771  DPALLVEDEVTVAIQVKGKLRDTITVAKGTAKeelealalaSEKVQRALDGAEVRKVIVV  830
            D + LVE++V + +Q+KGK++  + VAK+ ++EEL+ +ALA+EKVQ  + G ++ KVI V
Sbjct  764  DESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAV  823

Query  831  PDRLVNLV  838
            P++LVN+V
Sbjct  824  PNKLVNIV  831

1401) leuS in NC_019673


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  525 bits (1982),  Expect = 5e-150, Method: Compositional matrix adjust.
 Identities = 349/717 (49%), Positives = 502/717 (71%), Gaps = 39/717 (5%)

Query  214  LAYLSEAPVNWCPGLGTVLANEEVTADGRSERGNFPVFRRSLRQWMMRITAYSdrliddl  273
            LAY +E PVNW   LGT +ANEEV +DG SERG +PV R+++RQWM++ITAY++RL++DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  274  drldWPEKVKSMQRNWIGRSHGARVRFAV--GGHDIEVFTTRPDTLFGATYVVLAPEHPL  331
            + +DWPE +K MQRNWIG+S GA V F V   + D+ VFTTRPDTLFGATY VLAPEH+L
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  332  VDEIAAADRVGAIAEYRRAVARKSDLDRQE-NKEKTGVFTGAHAVNPVTGAEIPVYVADY  390
            VD I+++D+  A+A+Y+R  + KSDL R +  KEKTGV TG+ A+NPV G E+PV +ADY
Sbjct  268  VDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAINPVNGKEMPVWIADY  327

Query  391  VLMGYGTGAIMAVPGQDQRDWDFATAFDLPIIRTVRPPDGFEGEAYTGTGPAVNSGFLDG  450
            VL +YGTGAIMAVP++D+RDW+FA  F+L II  +   +  E  A+T  G  +NS+FLDG
Sbjct  328  VLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNV-EEAAFTEDGLHINSDFLDG  386

Query  451  LDVAEAKKTIIAWLEEHDRGEGTVQFKLRDWLFSRQRYWGEPFPIVYDEAGTPIAVPESM  510
            LD A A   ++ WLE ++ G+  V ++LRDWLFSRQRYWGEP+PI+  E GT+ AVPES 
Sbjct  387  LDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESE  446

Query  511  LPIELPDVDDYSPRTFEPDDANSEPSPPLSRAGEWVEVELDLGDGPKKYRRETNTMPNWA  570
            LP+ LP   D  P        ++   +PL+   +W+EV  +  DG K  RRETNTMP+WA
Sbjct  447  LPLVLPVTKDIRP--------SGTGESPLANVTDWLEVTRE--DGVKG-RRETNTMPQWA  495

Query  571  GSCWYQLRYVDPTETERFVNAENERYWLGPRAEHGANDPGGVDLYIGGVEHAVLHLLYSR  630
            GS WY LRY+DP +TE++ + E  + WL             VD+Y+GG EHAVLHLLY+R
Sbjct  496  GSSWYYLRYIDPHNTEKLADEELLKQWL------------PVDIYVGGAEHAVLHLLYAR  543

Query  631  FWQKVLFDLGHVSGDEPYRRLFNQGYIEAYAYRDERGTPVPAEQVEERDGKYFF--EGAE  688
            FW+KVL+DLG V+  EP+++LFNQG I + +YRD RG+ V++++VE RDG +F    G E
Sbjct  544  FWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEE  603

Query  689  VKREYGKMGKSLKNVVTPDDMCDRYGVDTFRLYEMSMGPMDVSRPWATKDVVGAQRFLQR  748
            + +  +KM+KSLKNVV PDD+ ++YG DT+R+YEM MGP+D S +W+  ++ G+++FL+R
Sbjct  604  LEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR  663

Query  749  LWRNLVDEETGALRVTDEEPAEDALRLLHKTIAGVHDDYANLRYNTAGAKLIELNNFVTK  808
            + R +   E     +T+E+++    ++ + T+ +V ++  ++++NTA A+L+ + N   K
Sbjct  664  VYRLITTKE-----ITEENSGALD-KVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANK  717

Query  809  HFPGGAPRALAEPMVLLLAPLCPHVAEELWAKL-GHAESLAHGPFPRAEEKFLVEDTVEY  867
            +  +      A   V L+AP+ PH++EELW  L + +ES++  P P  +E  LVE+ VE 
Sbjct  718  E--DKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEI  775

Query  868  PIQVNGkvkarvvvaasasPDEVKAAALGDPKVAELLTG-EPRKVIVVPGRLVNVVL  923
             +Q++GKVKA++VVA   S +E++  AL++ KV   ++G +  KVI VP +LVN+V+
Sbjct  776  VVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832


 Score =  124 bits (455),  Expect = 2e-29, Method: Compositional matrix adjust.
 Identities = 64/120 (54%), Positives = 89/120 (75%), Gaps = 0/120 (0%)

Query  46   GEVPADKLFVQDMFPYPSGAGLHVGHPLGFIGTDVFARYHRMTGRNVLHTMGFDAFGLPA  105
             + +  K++  DMFPYPSGAGLHVGHP G+ +TD+++R+ R  G+NVLH MG DAFGLPA
Sbjct  27   TDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSRFKRAQGHNVLHPMGWDAFGLPA  86

Query  106  EQYAVQTGQHPRATTEANIQTYLRQIRRVGLGHDERRRISTIDPGYYKWTQWIFLQIFNS  165
            EQYA++TG++P   T  NI  + RQI  +G++ D  R ++T DP YYKWTQWIF ++++ 
Sbjct  87   EQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEK  146

1402) leuS in NC_018524


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  525 bits (1981),  Expect = 5e-150, Method: Compositional matrix adjust.
 Identities = 349/854 (41%), Positives = 532/854 (63%), Gaps = 62/854 (7%)

Query  14   YDARALQDKWQARWAAELPFQASEDPGDDRPRSFVVDMFAYPSG-DLHMGHAEAYAIGDV  72
            YD  A++ KWQA WA +  F+++ D++  +P+ + +DMF+YPSG +LH+GH+E+Y+  D+
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDAS--KPKFYALDMFPYPSGAGLHVGHPEGYTATDI  61

Query  73   IGRYRLQRGDNVLHPVGWDSFGLPAENAAIKNNSHPEKWTYANIETQAASMGRYGVAVDW  132
            ++R++  +G+NVLHP+GWD+FGLPAE+ A+   ++P   T  NI      +   G + DW
Sbjct  62   LSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDW  121

Query  133  SRRIHTSDPEYFKWNQWLFTRFFDRGLAYRKDGLVNWCPQDQTVLANEQVV-QGRCERCG  191
             R ++T+DP+Y+KW QW+FT+++++GLAY  +  VNW  +  T +ANE+V+ +G  ER G
Sbjct  122  DREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGG  181

Query  192  AEVERRALNQWYFKITDYAQRLLDDMDQLDGGRWPDEVLAMQRNWIGRSTGADVHFEIEG  251
              V R+++ QW +KIT YA+RLL+D++++D   WP+ +  MQRNWIG+STGA+V F + +
Sbjct  182  YPVVRKPMRQWMLKITAYAERLLEDLEEVD---WPESIKDMQRNWIGKSTGANVTFKVKD  238

Query  252  RDEPVTVFTTRPDTLYGATFFVVaadaelaeelcapeQREAFETYRSDVAKLSDIERQTT  311
             D   TVFTTRPDTL+GAT+ V+A++  L + + +++Q EA   Y+ + +  SD+ R   
Sbjct  239  TDKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDL  298

Query  312  ERPKTGVFLGRYAVNPVTGERMPVWAADYVLAGYGHGAIMAVPAHDQRDLDFALAFDLPV  371
             + KTGV  G YA+NPV G  MPVW ADYVLA+YG GAIMAVPAHD+RD +FA  F+L +
Sbjct  299  AKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDI  358

Query  372  RVVVETGEPDPAETGVATAGEGVLRDSGPLDGLSKDEAIERIIEVLAERGTGEATVNYRL  431
              V+E G+ + A    A + +G+  +S+ LDGL K  AI +++E L   G G+  V YRL
Sbjct  359  IPVLEGGNVEEA----AFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRL  414

Query  432  RDWLLSRQRYWGTPIPIVHCPSCGEVAVPDEQLPVTLPELKGAELAPKGISPLAAAKDWV  491
            RDWL+SRQRYWG PIPI+H       AVP+ +LP+ LP  K+   +  G SPLA   DW+
Sbjct  415  RDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWL  474

Query  492  EVDCPSCGGPAERDTDTMDTFVDSSWYFLRYCSPHLDTAPFDTEAVNKWGPVDHYIGGKE  551
            EV     G  + R+T+TM    +SSWY+LRY  PH      D E +++W PVD Y+GG E
Sbjct  475  EVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAE  533

Query  552  HATLHLMYARFFTKVLHDMGMLDFTEPFARLTNQGQVIN----EGRA-------------  594
            HA LHL+YARF  KVL D+G++   EPF +L NQG ++     ++R+             
Sbjct  534  HAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDG  593

Query  595  -----------------MSKSLGNGVDLGKEIDAYGVDAVRLTMLFASPPEEDVDWADVS  637
                             MSKSL N V+ +  ++ YG D++R+  +F +P +  + W++ +
Sbjct  594  SFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEG  653

Query  638  PTAALKFLNRAYRVMHEagaagtpgadpatgdVELRRITHRSIDQITALIEDKRFNVAIA  697
              ++ KFL+R YR++       T           L ++ + ++  +T  +++ +FN AIA
Sbjct  654  LEGSRKFLDRVYRLI-------TTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIA  706

Query  698  RCMELVSATRKAIDSGPGAGDPavreaaefvavaLSLFAPYVAEEGWEKLGHVG-TVAAG  756
            + M +V+A+ K         D    + A      ++ FAP ++EE W+ L   G +++  
Sbjct  707  QLMVFVNAANKE--------DKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYV  758

Query  757  NWPEADPellvqetvtcvvqvQNKVRDKLAVAPDISDEELERLALASEKAQGFIGDKTVR  816
             WP  D   LV++ V  VVQ++ KV+ KL VA D+S EEL+ +ALA+EK Q+ I++K + 
Sbjct  759  PWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDII  818

Query  817  KVIVRAPKLVNIVV  830
            KVI  + KLVNIV+
Sbjct  819  KVIAVPNKLVNIVI  832

1403) leuS in NC_016801


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  525 bits (1979),  Expect = 8e-150, Method: Compositional matrix adjust.
 Identities = 349/737 (48%), Positives = 509/737 (70%), Gaps = 57/737 (7%)

Query  228  LVYRSHSMVNWCPGLGTVLANEEVTADGRSERGNFPVFRKKLSQWMMRITAYSdrliddl  287
            L Y ++  VNW   LGT +ANEEV +DG SERG +PV RK + QWM++ITAY++RL++DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  288  dlldwpdKVKSMQRNWIGRSRGAEVDFD--ALGHTITVFTTRPDTLFGASYMVLAPEHEL  345
            + +DWP+ +K MQRNWIG+S GA+V F     +  +TVFTTRPDTLFGA+Y VLAPEH L
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  346  VDALVAAGTNSYEGIDPRWTFGQATPAEAVKAYRASIAAKSDLERQE-NKEKTGVYLGVN  404
            VDA+ +++                  AEAV  Y+   + KSDL R +  KEKTGV  G  
Sbjct  268  VDAITTSD-----------------QAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSY  310

Query  405  AVNPVNGESIPVFIGDYVLTGYGTGAIMAVPAHDTRDYEFATEFGLPIREVVAGGNIAEA  464
            A+NPVNG  +PV I+DYVL++YGTGAIMAVPAHD RD EFA +F L I  V+ GGN+ EA
Sbjct  311  AINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEA  370

Query  465  AYTESGTAVNSANDQGLDINGLDKQEAIARVIEWLVDKQKGSEKIQYKLRDWLFARQRYW  524
            A+TE G  +NS       ++GLDK  AIA+++EWL     G+E++ Y+LRDWLF+RQRYW
Sbjct  371  AFTEDGLHINSDF-----LDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYW  425

Query  525  GEPFPVVYDENGLAHALPESMLPVELPEVEDYKPVSFDPDDADSEPHPPLAKATEWTQVE  584
            GEP+P++  E+G + A+PES LP+ LP   D +P         +  ++PLA+ T+W +V 
Sbjct  426  GEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTDWLEVT  477

Query  585  LDLGDGLKKYTRDTNVMPQWAGSSWYQLRYIDPTNSEAFCDIENERYWTGPRSAEDSGGV  644
             +  DG+K   R+TN MPQWAGSSWY LRYIDP N+E + D E  + W           V
Sbjct  478  RE--DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLP---------V  525

Query  645  DLYVGGVEHAVLHLLYSRFWHKVLFDLGFVTSREPYRRLFNQGYIQAFAYTDSRGVYVPA  704
            D+YVGG EHAVLHLLY+RFWHKVL+DLG V ++EP+++LFNQG I + +Y DSRG  V++
Sbjct  526  DIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVAT  585

Query  705  EEVEEKDGKFYY--QGEEVNQEYGKMGKSLKNAVAPDDICRDFGADTLRVYEMAMGPLDT  762
            + VE +DG F+    GEE++Q  +KM+KSLKN V PDD+  ++GADTLRVYEM MGPLD+
Sbjct  586  DKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  763  SRPWSTKDVIGAHRFLQRLWRLVVSEDDGSIVVTDAALTDDDLKQLHRTIAGMRDDYENL  822
            S +WS  ++ G+++FL+R+ RL+ + +   I   +++  D   K  + T+ ++ ++ +++
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLITTKE---ITEENSGALD---KVYNETVKAVTEQVDQM  699

Query  823  RINTVVAKAIEYVNYLTKAYGSTGAPRAAVEPLVIMVAAVAPHIAEELWKRL-GHNDTIT  881
            ++NT +A+ + +VN   K              +V ++A+ APH++EELW+ L +  ++I+
Sbjct  700  KFNTAIAQLMVFVNAANKE---DKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESIS  756

Query  882  FVPFPEYEDKWLVDDEVEMPVQINGKVRARIMVPADATQEQISEIALASDAVTTHIEGKN  941
            +VP P Y++  LV+++VE+ VQI+GKV+A+++V+ D ++E++ E+ALA++ V ++I GK+
Sbjct  757  YVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKD  816

Query  942  VVKKIVVPGRMVNLVVK  958
            ++K I VP ++VN+V+K
Sbjct  817  IIKVIAVPNKLVNIVIK  833


 Score =  140 bits (513),  Expect = 6e-34, Method: Compositional matrix adjust.
 Identities = 80/147 (55%), Positives = 104/147 (71%), Gaps = 10/147 (6%)

Query  27   IERSWQQYWIDNGTFNAPNPVGDLAVSGDKLPEDKLFVQDMFPYPSGAGLHVGHPLGYIA  86
            IE  WQ +W DN TF+          +G   +  K++  DMFPYPSGAGLHVGHP GY A
Sbjct  9    IEPKWQAFWADNHTFK----------TGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTA  58

Query  87   TDVFARFNRMLGKNVLHTLGYDAFGLPAEQYAIQTGTHPRTTTMANIANMQRQLGALGLG  146
            TD+++RF+R  G NVLH +G DAFGLPAEQYA++TG +P   T  NIAN +RQ+ ALG++
Sbjct  59   TDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFS  118

Query  147  HDPRRSVATTDPEFYKWTQWIFLQIFN  173
             D  R V TTDP++YKWTQWIF ++++
Sbjct  119  YDWDREVNTTDPNYYKWTQWIFTKLYE  145

1404) leuS in NC_012590


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  524 bits (1977),  Expect = 1e-149, Method: Compositional matrix adjust.
 Identities = 351/746 (48%), Positives = 497/746 (67%), Gaps = 72/746 (9%)

Query  216  LVYLSNSTVNWCPGLGTVLANEEVTAEGKSERGNFPVFRKNLRQWMMRITAYSdrllddl  275
            L Y ++  VNW   LGT +ANEEV ++G SERG +PV RK +RQWM++ITAY++RLL+DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  276  elldWPEKVKSMQRNWIGRSRGAEVSFHAEGYNID--VFTTRPDTLFGAEYVVLAPEHEL  333
            E +DWPE +K MQRNWIG+S GA+V+F   + + D  VFTTRPDTLFGA Y VLAPEH L
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  334  VDALLSPIPYEDDVDKRWTFGHDDPKEAVEAYRASIAAKSDLERQE-NKEKTGVFLGTYA  392
            VDA+ ++                D  EAV  Y+   + KSDL R +  KEKTGV  G+YA
Sbjct  268  VDAITTS----------------DQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYA  311

Query  393  TNPVNGKQIPIFIADYVLTGYGTGAIMAVPAHDTRDYEFATVFGLPITEVVAGGDITKEA  452
             NPVNGK++P+ IADYVL++YGTGAIMAVPAHD RD EFA  F L I  V+ GG++   A
Sbjct  312  INPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEAA  371

Query  453  YTESGQAVNSANDSLDINGMSKDEAIATIIPWLEEQGVGREKIQYKLRDWLFARQRYWGE  512
            +TE G  +NS      ++G+ K  AIA ++ WLE +GVG E++ Y+LRDWLF+RQRYWGE
Sbjct  372  FTEDGLHINSDF----LDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGE  427

Query  513  PFPIVYDEAGQAYPLPESMLPIELPEVEDYKpvsfdpddadsspqppLAKAREWVEVELD  572
            P+PI+  E G + ++PES LP+ LP   D +P + +           LA+  +W+EV  +
Sbjct  428  PIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESP--------LANVTDWLEVTRE  479

Query  573  LGLGDGPKTYYRDTNVMPQWAGSSWYQLRYIDPTNDEIFCDLENERYWTGPRTEEHGAND  632
             G+ +      R+TN MPQWAGSSWY LRYIDP N E + D E  + W            
Sbjct  480  DGVKGR-----RETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLP----------  524

Query  633  PGGVDLYVGGVEHAVLHLLYARFWHKVLFDLGYVSSKEPYRRLYNQGYIQAYAYTDSRGV  692
               VD+YVGG EHAVLHLLYARFWHKVL+DLG V++KEP+++L+NQG I + +Y DSRG 
Sbjct  525  ---VDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGA  581

Query  693  YVPAAEVEEKDGKFYY--NGEEVNQEYGKMGKSLKNSVAPDDICRDYGADTLRVYEMSMG  750
             V++  VE +DG F+    GEE++Q  +KM+KSLKN V PDD+  +YGADTLRVYEM MG
Sbjct  582  LVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMG  641

Query  751  PLDTSRPWATKDVVGAQRFLQRLWRLAIDENSGELSTTDAELSEDDLKHLNRTIAGVRDD  810
            PLD+S +W+  ++ G+++FL+R+ RL    +  E ++   +      K  N T+ +V ++
Sbjct  642  PLDASIAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALD------KVYNETVKAVTEQ  695

Query  811  YENLRLNTVVAKLIEYVNYLTK------AYPKGAPRAAVEPLAQLVSPVAPHIAEELWKR  864
             +++++NT +A+L+ +VN   K       Y+KG        + QL++P APH++EELW+ 
Sbjct  696  VDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKG--------FVQLIAPFAPHLGEELWQA  747

Query  865  FGHEG-TITYEAFPEFDEKYLVDDEIEVPVQINGKVKARVMVPADADQATVVGIAKDDER  923
            +   G +I+Y + P +DE  LV++++E+ VQI+GKVKA+++V+ D  +  +  +A  +E+
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  924  IAELTAGKNVVKEIYVPGRMVNLVVK  949
            +    AGK+++K I VP ++VN+V+K
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVIK  833


 Score =  134 bits (490),  Expect = 4e-32, Method: Compositional matrix adjust.
 Identities = 78/149 (53%), Positives = 101/149 (68%), Gaps = 10/149 (6%)

Query  18   AQIESAWQQYWKDNGTFNAPNPVGPLAEEGKELPAEKMNIQDMFPYPSGAGLHVGHPLGY  77
            + IE+ WQ +W DN TF++          G + +  K    DMFPYPSGAGLHVGHP GY
Sbjct  7    TAIEPKWQAFWADNHTFKT----------GTDASKPKFYALDMFPYPSGAGLHVGHPEGY  56

Query  78   IATDTYARFNRMLGKNVLHTLGYDAFGLPAEQYAIQTGTHPRTTTEANINNMRRQLGMLG  137
             ATD  +RF+R  G NVLH +G DAFGLPAEQYA++TG +P   T  NI N +RQ+  LG
Sbjct  57   TATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALG  116

Query  138  LGHDPRRSVASTDPEFYKWTQWIFLQIYN  166
            ++ D  R V +TDP++YKWTQWIF ++Y+
Sbjct  117  FSYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1405) leuS in NC_016782


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  524 bits (1976),  Expect = 1e-149, Method: Compositional matrix adjust.
 Identities = 351/737 (48%), Positives = 508/737 (69%), Gaps = 57/737 (7%)

Query  228  LVYRSHSMVNWCPGLGTVLANEEVTADGRSERGNFPVFRKKLSQWMMRITAYSdrliddl  287
            L Y ++  VNW   LGT +ANEEV +DG SERG +PV RK + QWM++ITAY++RL++DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  288  dlldwpdKVKSMQRNWIGRSRGAEVDFD--ALGHTITVFTTRPDTLFGASYMVLAPEHEL  345
            + +DWP+ +K MQRNWIG+S GA+V F     +  +TVFTTRPDTLFGA+Y VLAPEH L
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  346  VDALVAAGTNSYEGIDPRWTFGQATPAEAVKAYRASIAAKSDLERQE-NKEKTGVYLGVN  404
            VDA+ +++                  AEAV  Y+   + KSDL R +  KEKTGV  G  
Sbjct  268  VDAITTSD-----------------QAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSY  310

Query  405  AVNPVNGESIPVFIGDYVLTGYGTGAIMAVPAHDTRDYEFATEFGLPIREVVAGGNIAEA  464
            A+NPVNG  +PV I+DYVL++YGTGAIMAVPAHD RD EFA +F L I  V+ GGN+ EA
Sbjct  311  AINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEA  370

Query  465  AYTESGAAVNSANDQGLDINGLDKQEAIAQVIEWLVDKQKGSEKIQYKLRDWLFARQRYW  524
            A+TE G  +NS       ++GLDK  AIA+++EWL     G+E++ Y+LRDWLF+RQRYW
Sbjct  371  AFTEDGLHINSDF-----LDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYW  425

Query  525  GEPFPVVYDENGLAHALPESMLPVELPEVEDYKPVSFDPDDADSEPHPPLAKATEWTQVE  584
            GEP+P++  E+G + A+PES LP+ LP   D +P         +  ++PLA+ T+W +V 
Sbjct  426  GEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTDWLEVT  477

Query  585  LDLGDGLKKYTRDTNVMPQWAGSSWYQLRYIDPTNSEAFCDIENERYWTGPRSAEDSGGV  644
             +  DG+K   R+TN MPQWAGSSWY LRYIDP N+E + D E  + W           V
Sbjct  478  RE--DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLP---------V  525

Query  645  DLYVGGVEHAVLHLLYSRFWHKVLFDLGFVTSREPYRRLFNQGYIQAFAYTDSRGVYVPA  704
            D+YVGG EHAVLHLLY+RFWHKVL+DLG V ++EP+++LFNQG I + +Y DSRG  V++
Sbjct  526  DIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVAT  585

Query  705  EEVEEKDGKFYY--QGEEVNQEYGKMGKSLKNAVAPDDICRDFGADTLRVYEMAMGPLDT  762
            + VE +DG F+    GEE++Q  +KM+KSLKN V PDD+  ++GADTLRVYEM MGPLD+
Sbjct  586  DKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  763  SRPWSTKDVIGAHRFLQRLWRLVVSEDDGSIVVTDAALTDDDLKQLHRTIAGMRDDYEGL  822
            S +WS  ++ G+++FL+R+ RL+ + +   I   +++  D   K  + T+ ++ ++ + +
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLITTKE---ITEENSGALD---KVYNETVKAVTEQVDQM  699

Query  823  RINTVVAKAIEYVNYLTKAYGSTGAPRAAVEPLVIMVAAVAPHIAEELWKRL-GHNDTIT  881
            ++NT +A+ + +VN   K              +V ++A+ APH++EELW+ L +  ++I+
Sbjct  700  KFNTAIAQLMVFVNAANKE---DKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESIS  756

Query  882  FVPFPEYEDKWLVDDEVEMPVQINGKVRARIMVPADASQDQISEIALASEAVATHIEGKN  941
            +VP P Y++  LV+++VE+ VQI+GKV+A+++V+ D S++++ E+ALA+E V ++I GK+
Sbjct  757  YVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKD  816

Query  942  VIKKIVVPGRMVNLVVK  958
            +IK I VP ++VN+V+K
Sbjct  817  IIKVIAVPNKLVNIVIK  833


 Score =  140 bits (514),  Expect = 5e-34, Method: Compositional matrix adjust.
 Identities = 80/149 (54%), Positives = 104/149 (70%), Gaps = 10/149 (6%)

Query  25   GEIERSWQQYWIDNGTFNAPNPVGDLAVSGDKLPEDKLFVQDMFPYPSGAGLHVGHPLGY  84
              IE  WQ +W DN TF+          +G   +  K++  DMFPYPSGAGLHVGHP GY
Sbjct  7    TAIEPKWQAFWADNHTFK----------TGTDASKPKFYALDMFPYPSGAGLHVGHPEGY  56

Query  85   IATDVFARFNRMLGKNVLHTLGYDAFGLPAEQYAIQTGTHPRTTTMANIANMQRQLGALG  144
             ATD+++RF+R  G NVLH +G DAFGLPAEQYA++TG +P   T  NIAN +RQ+ ALG
Sbjct  57   TATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALG  116

Query  145  LGHDPRRSVATTDPEFYKWTQWIFLQIFN  173
            ++ D  R V TTDP++YKWTQWIF ++++
Sbjct  117  FSYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1406) leuS in NC_016799


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  524 bits (1976),  Expect = 1e-149, Method: Compositional matrix adjust.
 Identities = 349/737 (48%), Positives = 506/737 (69%), Gaps = 57/737 (7%)

Query  228  LVYRSHSMVNWCPGLGTVLANEEVTADGRSERGNFPVFRKKLSQWMMRITAYSdrliddl  287
            L Y ++  VNW   LGT +ANEEV +DG SERG +PV RK + QWM++ITAY++RL++DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  288  dlldwpdKVKSMQRNWIGRSRGAEVDFD--ALGHTITVFTTRPDTLFGASYMVLAPEHEL  345
            + +DWP+ +K MQRNWIG+S GA+V F     +  +TVFTTRPDTLFGA+Y VLAPEH L
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  346  VDALVAAGTNSYEGIDPRWTFGQATPAEAVKAYRASIAAKSDLERQE-NKEKTGVYLGVN  404
            VDA+ +++                  AEAV  Y+   + KSDL R +  KEKTGV  G  
Sbjct  268  VDAITTSD-----------------QAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSY  310

Query  405  AVNPVNGESIPVFIGDYVLTGYGTGAIMAVPAHDTRDYEFATEFGLPIREVVAGGNIAEE  464
            A+NPVNG  +PV I+DYVL++YGTGAIMAVPAHD RD EFA +F L I  V+ GGN+ E 
Sbjct  311  AINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEA  370

Query  465  AYTESGAAVNSANDQGLDINGLDKQEAIARVIEWLVDKQKGSEKIQYKLRDWLFARQRYW  524
            A+TE G  +NS       ++GLDK  AIA+++EWL     G+E++ Y+LRDWLF+RQRYW
Sbjct  371  AFTEDGLHINSDF-----LDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYW  425

Query  525  GEPFPVVYDENGLAHALPESMLPVELPEVEDYKPVSFDPDDADSEPHPPLAKATEWTQVE  584
            GEP+P++  E+G + A+PES LP+ LP   D +P         +  ++PLA+ T+W +V 
Sbjct  426  GEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTDWLEVT  477

Query  585  LDLGDGLKKYTRDTNVMPQWAGSSWYQLRYIDPTNSEAFCDIENERYWTGPRSAEDSGGV  644
             +  DG+K   R+TN MPQWAGSSWY LRYIDP N+E + D E  + W           V
Sbjct  478  RE--DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLP---------V  525

Query  645  DLYVGGVEHAVLHLLYSRFWHKVLFDLGFVTSREPYRRLFNQGYIQAFAYTDSRGVYVPA  704
            D+YVGG EHAVLHLLY+RFWHKVL+DLG V ++EP+++LFNQG I + +Y DSRG  V++
Sbjct  526  DIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVAT  585

Query  705  EEVEEKDGKFYY--QGEEVNQEYGKMGKSLKNAVAPDDICRDFGADTLRVYEMAMGPLDT  762
            + VE +DG F+    GEE++Q  +KM+KSLKN V PDD+  ++GADTLRVYEM MGPLD+
Sbjct  586  DKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  763  SRPWSTKDVIGAHRFLQRLWRLVVSEDDGSIVVTDAALTDDDLKQLHRTIAGMRDDYEGL  822
            S +WS  ++ G+++FL+R+ RL+ + +     +T+      D K  + T+ ++ ++ + +
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLITTKE-----ITEENSGALD-KVYNETVKAVTEQVDQM  699

Query  823  RINTVVAKAIEYVNYLTKAYGSTGAPRAAVEPLVIMVAAVAPHIAEELWKRL-GHNDTIT  881
            ++NT +A+ + +VN   K              +V ++A+ APH++EELW+ L +  ++I+
Sbjct  700  KFNTAIAQLMVFVNAANKE---DKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESIS  756

Query  882  FVPFPEYEDKWLVDDEVEMPVQINGKVRARIMVPADASQDQISEIALASDAVTTHIEGKN  941
            +VP P Y++  LV+++VE+ VQI+GKV+A+++V+ D S++++ E+ALA++ V ++I GK+
Sbjct  757  YVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKD  816

Query  942  VIKKIVVPGRMVNLVVK  958
            +IK I VP ++VN+V+K
Sbjct  817  IIKVIAVPNKLVNIVIK  833


 Score =  140 bits (513),  Expect = 5e-34, Method: Compositional matrix adjust.
 Identities = 80/149 (54%), Positives = 104/149 (70%), Gaps = 10/149 (6%)

Query  25   GEIERSWQQYWIDNGTFNAPNPVGDLAVSGDKLPEDKLFVQDMFPYPSGAGLHVGHPLGY  84
              IE  WQ +W DN TF+          +G   +  K++  DMFPYPSGAGLHVGHP GY
Sbjct  7    TAIEPKWQAFWADNHTFK----------TGTDASKPKFYALDMFPYPSGAGLHVGHPEGY  56

Query  85   IATDVFARFNRMLGKNVLHTLGYDAFGLPAEQYAIQTGTHPRTTTMANIANMQRQLGALG  144
             ATD+++RF+R  G NVLH +G DAFGLPAEQYA++TG +P   T  NIAN +RQ+ ALG
Sbjct  57   TATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALG  116

Query  145  LGHDPRRSVATTDPEFYKWTQWIFLQIFN  173
            ++ D  R V TTDP++YKWTQWIF ++++
Sbjct  117  FSYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1407) leuS in NC_016786


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  524 bits (1976),  Expect = 1e-149, Method: Compositional matrix adjust.
 Identities = 351/737 (48%), Positives = 508/737 (69%), Gaps = 57/737 (7%)

Query  228  LVYRSHSMVNWCPGLGTVLANEEVTADGRSERGNFPVFRKKLSQWMMRITAYSdrliddl  287
            L Y ++  VNW   LGT +ANEEV +DG SERG +PV RK + QWM++ITAY++RL++DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  288  dlldwpdKVKSMQRNWIGRSRGAEVDFD--ALGHTITVFTTRPDTLFGASYMVLAPEHEL  345
            + +DWP+ +K MQRNWIG+S GA+V F     +  +TVFTTRPDTLFGA+Y VLAPEH L
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  346  VDALVAAGTNSYEGIDPRWTFGQATPAEAVKAYRASIAAKSDLERQE-NKEKTGVYLGVN  404
            VDA+ +++                  AEAV  Y+   + KSDL R +  KEKTGV  G  
Sbjct  268  VDAITTSD-----------------QAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSY  310

Query  405  AVNPVNGESIPVFIGDYVLTGYGTGAIMAVPAHDTRDYEFATEFGLPIREVVAGGNIAEA  464
            A+NPVNG  +PV I+DYVL++YGTGAIMAVPAHD RD EFA +F L I  V+ GGN+ EA
Sbjct  311  AINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEA  370

Query  465  AYTESGAAVNSANDQGLDINGLDKQEAIAQVIEWLVDKQKGSEKIQYKLRDWLFARQRYW  524
            A+TE G  +NS       ++GLDK  AIA+++EWL     G+E++ Y+LRDWLF+RQRYW
Sbjct  371  AFTEDGLHINSDF-----LDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYW  425

Query  525  GEPFPVVYDENGLAHALPESMLPVELPEVEDYKPVSFDPDDADSEPHPPLAKATEWTQVE  584
            GEP+P++  E+G + A+PES LP+ LP   D +P         +  ++PLA+ T+W +V 
Sbjct  426  GEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTDWLEVT  477

Query  585  LDLGDGLKKYTRDTNVMPQWAGSSWYQLRYIDPTNSEAFCDIENERYWTGPRSAEDSGGV  644
             +  DG+K   R+TN MPQWAGSSWY LRYIDP N+E + D E  + W           V
Sbjct  478  RE--DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLP---------V  525

Query  645  DLYVGGVEHAVLHLLYSRFWHKVLFDLGFVTSREPYRRLFNQGYIQAFAYTDSRGVYVPA  704
            D+YVGG EHAVLHLLY+RFWHKVL+DLG V ++EP+++LFNQG I + +Y DSRG  V++
Sbjct  526  DIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVAT  585

Query  705  EEVEEKDGKFYY--QGEEVNQEYGKMGKSLKNAVAPDDICRDFGADTLRVYEMAMGPLDT  762
            + VE +DG F+    GEE++Q  +KM+KSLKN V PDD+  ++GADTLRVYEM MGPLD+
Sbjct  586  DKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  763  SRPWSTKDVIGAHRFLQRLWRLVVSEDDGSIVVTDAALTDDDLKQLHRTIAGMRDDYEGL  822
            S +WS  ++ G+++FL+R+ RL+ + +   I   +++  D   K  + T+ ++ ++ + +
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLITTKE---ITEENSGALD---KVYNETVKAVTEQVDQM  699

Query  823  RINTVVAKAIEYVNYLTKAYGSTGAPRAAVEPLVIMVAAVAPHIAEELWKRL-GHNDTIT  881
            ++NT +A+ + +VN   K              +V ++A+ APH++EELW+ L +  ++I+
Sbjct  700  KFNTAIAQLMVFVNAANKE---DKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESIS  756

Query  882  FVPFPEYEDKWLVDDEVEMPVQINGKVRARIMVPADASQDQISEIALASEAVATHIEGKN  941
            +VP P Y++  LV+++VE+ VQI+GKV+A+++V+ D S++++ E+ALA+E V ++I GK+
Sbjct  757  YVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKD  816

Query  942  VIKKIVVPGRMVNLVVK  958
            +IK I VP ++VN+V+K
Sbjct  817  IIKVIAVPNKLVNIVIK  833


 Score =  140 bits (514),  Expect = 5e-34, Method: Compositional matrix adjust.
 Identities = 80/149 (54%), Positives = 104/149 (70%), Gaps = 10/149 (6%)

Query  25   GEIERSWQQYWIDNGTFNAPNPVGDLAVSGDKLPEDKLFVQDMFPYPSGAGLHVGHPLGY  84
              IE  WQ +W DN TF+          +G   +  K++  DMFPYPSGAGLHVGHP GY
Sbjct  7    TAIEPKWQAFWADNHTFK----------TGTDASKPKFYALDMFPYPSGAGLHVGHPEGY  56

Query  85   IATDVFARFNRMLGKNVLHTLGYDAFGLPAEQYAIQTGTHPRTTTMANIANMQRQLGALG  144
             ATD+++RF+R  G NVLH +G DAFGLPAEQYA++TG +P   T  NIAN +RQ+ ALG
Sbjct  57   TATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALG  116

Query  145  LGHDPRRSVATTDPEFYKWTQWIFLQIFN  173
            ++ D  R V TTDP++YKWTQWIF ++++
Sbjct  117  FSYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1408) leuS in NC_016802


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  524 bits (1978),  Expect = 1e-149, Method: Compositional matrix adjust.
 Identities = 349/740 (48%), Positives = 512/740 (70%), Gaps = 63/740 (8%)

Query  254  LVYRSHSMVNWCPGLGTVLANEEVTADGRSERGNFPVFRKKLSQWMMRITAYSdrliddl  313
            L Y ++  VNW   LGT +ANEEV +DG SERG +PV RK + QWM++ITAY++RL++DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  314  dlldwpdKVKSMQRNWIGRSRGAEVDFD--ALGHTITVFTTRPDTLFGASYMVLAPEHEL  371
            + +DWP+ +K MQRNWIG+S GA+V F     +  +TVFTTRPDTLFGA+Y VLAPEH L
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  372  VDALVAAGTNSYEGIDPRWTFGQATPAEAVKAYRVSIAAKSDLERQE-NKEKTGVYLGVN  430
            VDA+ +++                  AEAV  Y+   + KSDL R +  KEKTGV  G  
Sbjct  268  VDAITTSD-----------------QAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSY  310

Query  431  AVNPVNGESIPVFIGDYVLTGYGTGAIMAVPAHDTRDYEFATEFGLPIREVVAGGNIAEA  490
            A+NPVNG  +PV I+DYVL++YGTGAIMAVPAHD RD EFA +F L I  V+ GGN+ EA
Sbjct  311  AINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEA  370

Query  491  AYTESGAAVNSANDQGLDINGLDKQEAIAQVIEWLVDKQKGSEKIQYKLRDWLFARQRYW  550
            A+TE G  +NS       ++GLDK  AIA+++EWL     G+E++ Y+LRDWLF+RQRYW
Sbjct  371  AFTEDGLHINSDF-----LDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYW  425

Query  551  GEPFPVVYDENGLAHALPESMLPVELPEVEDYKPVSFDPDDADSEPHPPLAKATEWTQVE  610
            GEP+P++  E+G + A+PES LP+ LP   D +P         +  ++PLA+ T+W +V 
Sbjct  426  GEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTDWLEVT  477

Query  611  LDLGDGLKKYTRDTNVMPQWAGSSWYQLRYIDPTNSEAFCDIENERYWTGPRSAEDSGGV  670
             +  DG+K   R+TN MPQWAGSSWY LRYIDP N+E + D E  + W           V
Sbjct  478  RE--DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLP---------V  525

Query  671  DLYVGGVEHAVLHLLYSRFWHKVLFDLGFVTSREPYRRLFNQGYIQAFAYTDSRGVYVPA  730
            D+YVGG EHAVLHLLY+RFWHKVL+DLG V ++EP+++LFNQG I + +Y DSRG  V++
Sbjct  526  DIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVAT  585

Query  731  EEVEEKDGKFYY--QGEEVNQEYGKMGKSLKNAVAPDDICRDFGADTLRVYEMAMGPLDT  788
            + VE +DG F+    GEE++Q  +KM+KSLKN V PDD+  ++GADTLRVYEM MGPLD+
Sbjct  586  DKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  789  SRPWSTKDVIGAHRFLQRLWRLVVSEDDGSIVVTDAALTDDDLKQLHRTIAGMRDDYENL  848
            S +WS  ++ G+++FL+R+ RL+ + +   I   +++  D   K  + T+ ++ ++ +++
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLITTKE---ITEENSGALD---KVYNETVKAVTEQVDQM  699

Query  849  RINTVVAKAIEYVNYLTKA---YGSTGAPRAAVAPLVIMVAAVAPHIAEELWKRL-GHND  904
            ++NT +A+ + +VN   K    ++  +        +V ++A+ APH++EELW+ L +  +
Sbjct  700  KFNTAIAQLMVFVNAANKEDKLFSDYA------KGFVQLIAPFAPHLGEELWQALTASGE  753

Query  905  TITFVPFPEYEDKWLVDDEVEMPVQINGKVRARIMVPADASQDQISEIALASDAVTTHIE  964
            +I++VP P Y++  LV+++VE+ VQI+GKV+A+++V+ D S++++ E+ALA++ V ++I 
Sbjct  754  SISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIA  813

Query  965  GKKVVKMIVVPGRMVNLVVK  984
            GK ++K+I VP ++VN+V+K
Sbjct  814  GKDIIKVIAVPNKLVNIVIK  833


 Score =  140 bits (514),  Expect = 5e-34, Method: Compositional matrix adjust.
 Identities = 80/147 (55%), Positives = 104/147 (71%), Gaps = 10/147 (6%)

Query  53   IERSWQQYWIDNGTFNAPNPVGDLAVSGDKLPEDKLFVQDMFPYPSGAGLHVGHPLGYIA  112
            IE  WQ +W DN TF+          +G   +  K++  DMFPYPSGAGLHVGHP GY A
Sbjct  9    IEPKWQAFWADNHTFK----------TGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTA  58

Query  113  TDVFARFNRMLGKNVLHTLGYDAFGLPAEQYAIQTGTHPRTTTMANIANMQRQLGALGLG  172
            TD+++RF+R  G NVLH +G DAFGLPAEQYA++TG +P   T  NIAN +RQ+ ALG++
Sbjct  59   TDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFS  118

Query  173  HDPRRSVATTDPEFYKWTQWIFLQIFN  199
             D  R V TTDP++YKWTQWIF ++++
Sbjct  119  YDWDREVNTTDPNYYKWTQWIFTKLYE  145

1409) leuS in NC_022115


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  524 bits (1976),  Expect = 1e-149, Method: Compositional matrix adjust.
 Identities = 350/738 (48%), Positives = 501/738 (68%), Gaps = 65/738 (8%)

Query  223  LVYQSDSMVNWCPGLGTVLANEEVTADGRSDRGNFPVFRKHLQQWMMRITAYSDRLVDDL  282
            L Y+++  VNW   LGT +ANEEV +DG S+RG +PV RK ++QWM++ITAY++RL++DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  283  EYLDWPDKVKAMQRNWIGRSYGAEVTFAAGEYGVD--VFTTRPDTLFGATYVTLAPEHDL  340
            E +DWP+ +K MQRNWIG+S GA+VTF   + + D  VFTTRPDTLFGATY  LAPEH L
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  341  VDKLVADEWPDGVDARWTGGATTPAEAVAAYRKSIAAKTDLERQE-NKEKTGVFLGSYAV  399
            VD + + +                AEAVA Y++  + K+DL R +  KEKTGV  GSYA+
Sbjct  268  VDAITTSD---------------QAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAI  312

Query  400  NPVNGHKVPIFIADYVLTGYGTGAIMAVPGHDHRDWEFANAFGLEILEVIAGGDVSEAAY  459
            NPVNG  +P+ IADYVL++YGTGAIMAVP+HD+RDWEFA+ F L+I+ V+ GG+V EAA+
Sbjct  313  NPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEAAF  372

Query  460  SGDGPLVNSDYLDGLDVAEAKATVISRLEESGQGKGTIQYKLRDWLFARQRYWGEPFPIV  519
            + DG  +NSD+LDGLD A A A ++ +LE  G G+  + Y+LRDWLF+RQRYWGEP+PI+
Sbjct  373  TEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPII  432

Query  520  YDADGNAHALPDSALPVVLPEVEDYAPVSFDPDDANSEPSPPLNKATDWVNVELDLGDGL  579
               DG + A+P+S LP+VLP   D  P        ++   +PL + TDW++V  +  DG+
Sbjct  433  HWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTDWLEVTRE--DGV  482

Query  580  QTYHRDTNVMPQWAGSSWYQLRYIDPTNQDAFCDPQNEAYWTGPRPELHGPNDPGGVDLY  639
            +  +R+TN MPQWAGSSWY LRYIDP N + + D +    W               VD+Y
Sbjct  483  KG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWL-------------PVDIY  528

Query  640  VGGVEHAVLHLLYSRFWHKVLFDLGYVSSSEPYRRLYNQGYIQAFAYTDARGVYVPAEEV  699
            VGG EHAVLHLLY+RFWHKVL+DLG V++ EP+++L+NQG I + +Y D+RG  V+++ V
Sbjct  529  VGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKV  588

Query  700  VERDGKFFF--EGAEVNREYGKMGKSLKNAVAPDEICAEFGADTLRVYEMSMGPLDTSRP  757
              RDG FF    G E+++  +KM+KSLKN V PD++  ++GADTLRVYEM MGPLD+S +
Sbjct  589  EKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIA  648

Query  758  WATKDVVGAARFLQRVWRVVIDEETGKPRVTDEAPGEETLRALNKAISGVIEDYTALRDN  817
            W+  ++ G+ +FL+RV R++   E     +T+E +G    +  N ++ +V E+   ++ N
Sbjct  649  WSEEGLEGSRKFLDRVYRLITTKE-----ITEENSGALD-KVYNETVKAVTEQVDQMKFN  702

Query  818  TAAAKLIEY------NNHLTKAFPGGAPRaaveplvlmlaplaphlaeelWSRL-GHTES  870
            TA A+L+ +      ++ L   ++ G  +        ++AP+APHL+EELW  L +  ES
Sbjct  703  TAIAQLMVFVNAANKEDKLFSDYAKGFVQ--------LIAPFAPHLGEELWQALTASGES  754

Query  871  LAHGPFPAVEEKWLVEDTVEYPIQVNGKVRSRISVPADADRKAVEEIALADEKIVALLEG  930
            ++  P P+ +E  LVE+ VE  +Q++GKV++++ V+ D  R  ++E+ALA+EK+ A + G
Sbjct  755  ISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAG  814

Query  931  KAPRKVIVVPGKMVNIVL  948
            K   KVI VP K+VNIV+
Sbjct  815  KDIIKVIAVPNKLVNIVI  832


 Score =  129 bits (474),  Expect = 7e-31, Method: Compositional matrix adjust.
 Identities = 83/194 (43%), Positives = 121/194 (63%), Gaps = 18/194 (9%)

Query  28   IEQHWQDRWSEDGTFNAPNPVGPLSSPDGVPADKLFVQDMFPYPSGSGLHVGHPLGYIAT  87
            IE  WQ  W+++ TF++           + +  K++  DMFPYPSG+GLHVGHP GY AT
Sbjct  9    IEPKWQAFWADNHTFKTGT---------DASKPKFYALDMFPYPSGAGLHVGHPEGYTAT  59

Query  88   DVFARFHRMQGRNVLHTLGYDAFGLPAEQYAVQTGTHPRTTTESNIANMKRQLRRLGLGH  147
            D+++RF R QG+NVLH +G DAFGLPAEQYA++TG +P   T  NIAN KRQ+  LG++ 
Sbjct  60   DILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSY  119

Query  148  DERRSLATTDVDFYHWTQWIFLQIHGAWYDK-----AAGKARRISELEAEFDSGERALED  202
            D  R + TTD ++Y WTQWIF ++    Y+K     A     ++ EL + + + E   ++
Sbjct  120  DWDREVNTTDPNYYKWTQWIFTKL----YEKGLAYEAEVPVNWVEELGTAIANEEVLPDG  175

Query  203  GREWASLTVAEKAK  216
              E+++  V  K+ 
Sbjct  176  TSERGGYPVVRKPM  189

1410) leuS in NC_012490


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  524 bits (1978),  Expect = 1e-149, Method: Compositional matrix adjust.
 Identities = 349/738 (48%), Positives = 502/738 (69%), Gaps = 65/738 (8%)

Query  223  LVYQSDSMVNWCPGLGTVLANEEVTADGRSDRGNFPVFRKHLQQWMMRITAYSDRLVDDL  282
            L Y+++  VNW   LGT +ANEEV +DG S+RG +PV RK ++QWM++ITAY++RL++DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  283  EYLDWPDKVKAMQRNWIGRSYGAEVTFAAGEYGVD--VFTTRPDTLFGATYVTLAPEHDL  340
            E +DWP+ +K MQRNWIG+S GA+VTF   + + D  VFTTRPDTLFGATY  LAPEH L
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  341  VDTLVADEWPEGVDARWTGGATTPAEAVAAYRKSIAAKTDLERQE-NKEKTGVFLGSYAV  399
            VD++ + +                AEAVA Y++  + K+DL R +  KEKTGV  GSYA+
Sbjct  268  VDAITTSD---------------QAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAI  312

Query  400  NPVNGHKVPIFIADYVLTGYGTGAIMAVPGHDHRDWEFANAFGLEILEVIAGGDVSEAAY  459
            NPVNG  +P+ IADYVL++YGTGAIMAVP+HD+RDWEFA+ F L+I+ V+ GG+V EAA+
Sbjct  313  NPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEAAF  372

Query  460  SGDGPLVNSDYLDGLDVAEAKATVISRLEESGQGKGTIQYKLRDWLFARQRYWGEPFPIV  519
            + DG  +NSD+LDGLD A A A ++ +LE  G G+  + Y+LRDWLF+RQRYWGEP+PI+
Sbjct  373  TEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPII  432

Query  520  YDADGNAHALPDSALPVVLPEVEDYAPVSFDPDDANSEPSPPLNKATDWVNVELDLGDGL  579
               DG + A+P+S LP+VLP   D  P        ++   +PL + TDW++V  +  DG+
Sbjct  433  HWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTDWLEVTRE--DGV  482

Query  580  QTYHRDTNVMPQWAGSSWYQLRYIDPTNQDAFCDPQNEAYWTGPRPELHGPNDPGGVDLY  639
            +  +R+TN MPQWAGSSWY LRYIDP N + + D +    W               VD+Y
Sbjct  483  KG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWL-------------PVDIY  528

Query  640  VGGVEHAVLHLLYSRFWHKVLFDLGYVSSSEPYRRLYNQGYIQAFAYTDARGVYVPAEEV  699
            VGG EHAVLHLLY+RFWHKVL+DLG V++ EP+++L+NQG I + +Y D+RG  V+++ V
Sbjct  529  VGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKV  588

Query  700  VERDGKFFY--EGAEVNREYGKMGKSLKNAVAPDEICAEFGADTLRVYEMSMGPLDTSRP  757
              RDG FF    G E+++  +KM+KSLKN V PD++  ++GADTLRVYEM MGPLD+S +
Sbjct  589  EKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIA  648

Query  758  WATKDVVGAARFLQRVWRVVIDEETGKPRVTDEAPGEETLRALNKAISGVIEDYTALRDN  817
            W+  ++ G+ +FL+RV R++   E     +T+E +G    +  N ++ +V E+   ++ N
Sbjct  649  WSEEGLEGSRKFLDRVYRLITTKE-----ITEENSGALD-KVYNETVKAVTEQVDQMKFN  702

Query  818  TAAAKLIEY------NNHLTKAFPGGAPRaaveplvlmlaplaphlaeelWSRL-GHTES  870
            TA A+L+ +      ++ L   ++ G  +        ++AP+APHL+EELW  L +  ES
Sbjct  703  TAIAQLMVFVNAANKEDKLFSDYAKGFVQ--------LIAPFAPHLGEELWQALTASGES  754

Query  871  LAHGPFPAVEEKWLVEDTVEYPIQVNGKVRSRISVPADADRKAVEEIALADEKIVALLEG  930
            ++  P P+ +E  LVE+ VE  +Q++GKV++++ V+ D  R  ++E+ALA+EK+ A + G
Sbjct  755  ISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAG  814

Query  931  NAPRKVIVVPGKMVNIVL  948
            +   KVI VP K+VNIV+
Sbjct  815  KDIIKVIAVPNKLVNIVI  832


 Score =  129 bits (474),  Expect = 7e-31, Method: Compositional matrix adjust.
 Identities = 83/194 (43%), Positives = 121/194 (63%), Gaps = 18/194 (9%)

Query  28   IEQHWQDRWSEDGTFNAPNPVGPLSSPDGVPADKLFVQDMFPYPSGSGLHVGHPLGYIAT  87
            IE  WQ  W+++ TF++           + +  K++  DMFPYPSG+GLHVGHP GY AT
Sbjct  9    IEPKWQAFWADNHTFKTGT---------DASKPKFYALDMFPYPSGAGLHVGHPEGYTAT  59

Query  88   DVFARFHRMQGRNVLHTLGYDAFGLPAEQYAVQTGTHPRTTTESNIANMKRQLRRLGLGH  147
            D+++RF R QG+NVLH +G DAFGLPAEQYA++TG +P   T  NIAN KRQ+  LG++ 
Sbjct  60   DILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSY  119

Query  148  DERRSLATTDVDFYHWTQWIFLQIHGAWYDK-----AAGKARRISELEAEFDSGERALED  202
            D  R + TTD ++Y WTQWIF ++    Y+K     A     ++ EL + + + E   ++
Sbjct  120  DWDREVNTTDPNYYKWTQWIFTKL----YEKGLAYEAEVPVNWVEELGTAIANEEVLPDG  175

Query  203  GREWASLTVAEKAK  216
              E+++  V  K+ 
Sbjct  176  TSERGGYPVVRKPM  189

1411) leuS in NC_015554


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  524 bits (1977),  Expect = 1e-149, Method: Compositional matrix adjust.
 Identities = 363/873 (42%), Positives = 559/873 (65%), Gaps = 54/873 (6%)

Query  6    YNPKDIEQRVQQYWEENNSFQANDDVEKEKFYCLSMFPYPSGR-LHMGHVRNYTIGDVIS  64
            Y+   IE + Q +W +N++F++  D  K KFY L MFPYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  65   RYQRMQGKNVLQPMGWDAFGLPaenaainnntapanWTYSNIDYMKTQLRSLGFGYDWDR  124
            R++R QG NVL+PMGWDAFGLPAE+ A++    PA+ T  NI   K Q+ +LGF+YDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  125  EVTTCKPDYYRWEQWFFTRLYEKGLVYKKNSTVNWDPVDQTVLANEQVI-DGRGWRSGAL  183
            EV T  P+YY+W QW+FT+LYEKGL Y  +  VNW     T +ANE+V+ DG + R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  184  VEQKEIPQWFIKITDYaeelladleqleeWPDQVRAMQANWIGRSEGVDITFNLGKNGSD  243
            V +K + QW +KIT Y  E L +  +  +WP+ ++ MQ NWIG+S G ++TF++   +  
Sbjct  184  VVRKPMRQWMLKITAY-AERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD--  240

Query  244  INDLTVYTTRPDTFYGVTYVAVAAQHPLAEFAAKTNAELATFIDECKNTKVAEAELA---  300
             +D+TV+TTRPDT++G TY  +A++H+L +  A T ++ A  + + K      ++LA   
Sbjct  241  -KDFTVFTTRPDTLFGATYAVLAPEHALVD--AITTSDQAEAVADYKRQASLKSDLARTD  297

Query  301  -TMEKKGCDTGIQAVHPLTGELLPVWVANFVLMDYGSGAVMAVPGHDQRDWEFATKYGLT  359
             + EK G  TG  A++P+ G  +PVW+A++VL  YG+GA+MAVP+HD+RDWEFA ++ L 
Sbjct  298  LAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLD  357

Query  360  IKQVIAPNADAKEECDLTVSAYTEKGTLINSEKFDGLAFDDAFNNIATALEEKGFGKRKV  419
            I  V+       E  ++  +A+TE G  INS+ +DGL    A+ ++   LE  G G+ +V
Sbjct  358  IIPVL-------EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENV  410

Query  420  NYRLRDWGVSRQRYWGSPIPMLNLENGesvpvpeselpvvlpeDVEM---NGVTSPIKAD  476
             YRLRDW  SRQRYWG PIP+++ E+G S +VPESELP+VLP   ++       SP+   
Sbjct  411  TYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANV  470

Query  477  PEWAKTTY-NGEPALRETDTFDTFMESSWYYARYASATNHDAMLDPTSSNYWLPVDQYIG  535
             +W   T  +G  + RET+T      SSWYY RY  + N + + D    + WLPVD Y+G
Sbjct  471  TDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVG  530

Query  536  GIEHAILHLLYSRFFHKLLRDEGLVNSDEPFKRLLCQGMVLADSYYREDDAGKKTWYSPT  595
            G EHA+LHLLY+RF HK+L D G+V + EPF++L+ QGM+L+ S YR+  ++        
Sbjct  531  GAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS-YRDSRGAL-------  582

Query  596  EVSTEKDEKGRIVKAWLTADGEPVIHGGMTKMSKSKNNGIDPQEVIDLYGADTVRLFTMF  655
             V+T+K EK     + +  +    ++ + +KMSKS +N ++P++V++ YGADT+R++ MF
Sbjct  583  -VATDKVEKRD--GSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMF  639

Query  656  AAPPEQTLEWVDSGVEGANRFLRRIWKLVTEHVEKGTPVALDAKALNKNQQALRREVHKT  715
             +P + ++ W + G+EG+ +FL R+ +L+T                + N  AL +  + T
Sbjct  640  MGPLDASIAWSEEGLEGSRKFLDRVYRLITTK-----------EITEENSGALDKVYNET  688

Query  716  IEKVSDDLGRRQTFNTAIAAIMELLNHLQKAPQEDAQDIAIMREAAESLVLLLNPITPHI  775
            +  V++++++ + FNTAIA +M ++N  +K  +       +  + A ++V L+ P++PH+
Sbjct  689  VKAVTEQVDQMK-FNTAIAQLMVFVNAANKEDK-------LFSDYAKGFVQLIAPFAPHL  740

Query  776  SHELWKVLGQTSD-IDHAPWPVADKAALVEDEKLIIVQVNGKVRAKMTVAADASKDAIEE  834
            ++ELW+ L  +++ I   PWP  D + LVE++  I+VQ++GKV+AK+ VA D S++ ++E
Sbjct  741  GEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQE  800

Query  835  AAKAQDNVQPFIEGKTIRKVIVVPGKLVNIVAN  867
             A A+++VQ+ I GK I KVI VP KLVNIV +
Sbjct  801  VALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

1412) Trad_2121 in NC_014221


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  524 bits (1978),  Expect = 8e-150, Method: Compositional matrix adjust.
 Identities = 378/857 (45%), Positives = 551/857 (65%), Gaps = 67/857 (7%)

Query  18   YNPQEIEPKWQARWAELKLYETDLESDQEPFYYLTMFPYPSG-DLHIGHWYAFSIPDAYA  76
            Y+   IEPKWQA WA+   + T+ ++ +  FY L MFPYPSG +LH+GH  +++  D  +
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  77   RFKRMRGLNVLFPMGFDAFGLPAENAAIKAARQGGSVHPATLTYERMAHMERQFAKMGAS  136
            RFKR +G NVL PMG DAFGLPAE+ A+ ++ +     PA +T E +A+  RQ+  +G S
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGND-----PAEFTAENIANFKRQINALGFS  118

Query  137  FDWSKKVVTCDPGYYRWNQLFFLRMLERGLAYRKASFVNWDPVDQTVLANEQVV-NGRGE  195
            +DW + V T DP YY+W Q +F ++ E+GLAY     VNW     T +ANE+V+ +G +E
Sbjct  119  YDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSE  178

Query  196  RSGALVERRLMPQWHFKITAYAEELL-DFSGLDWPEKVKLMQTNWIGRSEGAEVRFKT-E  253
            R+G  V R+ M QW +KITAYAE LL D+  +DWPE +K MQ NWIG+S GA+V FK  +
Sbjct  179  RGGYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKD  238

Query  254  SGDELVVFTTRPDTLWGVTFMVLAPEHPLVEKLTTPEQREAVARYVKAASHLSEIERQAT  313
            ++ ++ VFTTRPDTL G T+ VLAPEH+LV+ +TT++Q EAVA Y + AS  S++ R   
Sbjct  239  TDKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDL  298

Query  314  DKEKTGEFTGAFAINPVNGERVPIWIADYVMMGYGTGAVMAVPAHDERDFAFARAFGLPV  373
             KEKTG  TG++AINPVNG  +P+WIADYV+ +YGTGA+MAVPAHDERD  FA+ F L +
Sbjct  299  AKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDI  358

Query  374  KPVIAASEGAEVDGEAMTEAYTGDGVMVNSGPFDGTPTGKGTPEGIHKVIAWLEAKGKGK  433
             PV+   EG++V+      A+T DG+ +NS+ +DG     + + +I K++ WLEA G G+
Sbjct  359  IPVL---EGGNVEE----AAFTEDGLHINSDFLDGL----DKASAIAKMVEWLEAEGVGN  407

Query  434  GTVTYRLRDWLISRQRYWGTPIPVLYCDRCGLVPEREENLPVLLPEDVAFMP--TGESPL  491
              VTYRLRDWL+SRQRYWG PIP++  +     +  E +LP++LP    + P  TGESPL
Sbjct  408  ENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPL  467

Query  492  KHHAGFLNATCPSCGGPAQRETDTMDTFVDSSWYWFRYLSPDLQDAPIDRQRARRWTPVD  551
             + ++ L+ T    G  ++RET+TM    +SSWY +RY+ P+  +   D +  ++W PVD
Sbjct  468  ANVTDWLEVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVD  526

Query  552  QYTGGIEHAILHLLYARFFTKVLRDLGFVDVDEPFKRLRNQGMILG--------------  597
             Y GG EHA+LHLLYARF  KVL DLG V   EPF++L NQGMILG              
Sbjct  527  IYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATD  586

Query  598  -------------------EDNEKMSKSRGNVVNPDDLVAEYGADTVRAYLMFIGPWEAG  638
                               +   KMSKS  NVVNPDD+V +YGADT+R Y MF+GP +A+
Sbjct  587  KVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  639  GPWSSTGIEGVARFLNRVWALLTEPVEATGGDPETRKALRRAVHHAIKEVTEDLEAFGFN  698
             +WS  G+EG  +FL+RV  L+T    +     E   AL +  ++++K VTE+++   FN
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLIT----TKEITEENSGALDKVYNETVKAVTEQVDQMKFN  702

Query  699  TAVAELMTLTNAMSRAKPALAGTDVWEEATEalllllapiaphlaDELWER-SGRAGSVH  757
            TA+A+LM + NA ++    ++      + + +++ L+AP+APHL++ELW+  ++ + S+ 
Sbjct  703  TAIAQLMVFVNAANKEDKLFS------DYAKGFVQLIAPFAPHLGEELWQALTASGESIS  756

Query  758  QQVWPTPDEGALVQDTVTIAVQVSGKRRGEVTVPKGaddaavlaaakaepnvaRHLENAQ  817
               WP+ DE+ LV++ V I VQ+ GK ++ + V+K+     +   A A+ +V  ++   +
Sbjct  757  YVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKD  816

Query  818  VVREIVVPGRLVNIVVR  834
            +++ I VP +LVNIV++
Sbjct  817  IIKVIAVPNKLVNIVIK  833

1413) leuS in NC_008789


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  524 bits (1978),  Expect = 8e-150, Method: Compositional matrix adjust.
 Identities = 351/841 (42%), Positives = 532/841 (64%), Gaps = 75/841 (8%)

Query  23   TFQAREDSARPKYYCLSMFPYPSGR-LHMGHVRNYTIGDVVSRYKRMQGYNVLQPMGWDA  81
            TF++  D+++PK+Y L MFPYPSG  LH+GH   YT  D++SR+KR QG NVL+PMGWDA
Sbjct  22   TFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSRFKRAQGHNVLHPMGWDA  81

Query  82   FGLPAENAAMERGVPPAAWTRENIGAMREQLKGLGFGYDWSRELATCDPEYYRWEQWLFI  141
            FGLPAE+ AM+ G  PA  T ENI+  + Q+++LGF+YDW RE+ T DP+YY+W QW+F 
Sbjct  82   FGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFT  141

Query  142  RLYRKGLVYRDTAAVNWDPVDQTVLANEQVI-EGRGWRSGALVERREIPQWFLRITDYad  200
            +LY KGL Y    +VNW     T +ANE+V+ +G + R+G  V R+ + QW L+IT Y  
Sbjct  142  KLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAY-A  200

Query  201  ellealdeldGWPEQVRNMQRNWIGRSEGVELSFDLAGRDEQLTVFTTRPDTLYGVTYMG  260
            E L    E  +WPE +++MQRNWIG+S G +++F + + D ++TVFTTRPDTL+G TY  
Sbjct  201  ERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAV  260

Query  261  LAPEHPISLELAEHHPAIAELVEEARSGGTAEADLA----TREKRGADTGLEAIHPLTGE  316
            LAPEH++   ++  +   AE V + +  ++  +DLA    ++EK G  TG  AI+P+ G 
Sbjct  261  LAPEHALVDAITTSDQ--AEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAINPVNGK  318

Query  317  RIPVWVANFVLMEYGSGAVMAVPAHDQRDWEFASTYGLPIRPVVHPADGTELDIAAGAFS  376
             +PVW+A++VL  YG+GA+MAVPAHD+RDWEFA  + L I PV++ +     ++  +AF+
Sbjct  319  EMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGG-----NVEEAAFT  373

Query  377  DYGVLADSGPFSGMPSDRAFAAIAERLEAEGRGQRRVQYRLRDWGVSRQRYWGAPIPMIH  436
            + G+  +S+ + G+    A+A + E+LEAEG G+  V YRLRDW  SRQRYWG PIP+IH
Sbjct  374  EDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIH  433

Query  437  CADCGPVPVPDDQLPVTLPEDVEI---SGGGSPLKSMPAFYQTACPQCGADAERETDTFD  493
              D  + +VP+ +LP+ LP   +I   + G SPL ++    + +  + G  + RET+T  
Sbjct  434  WEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED-GVKGRRETNTMP  492

Query  494  TFMESSWYFARFACADQDGAMLDER-ADHWTPVDQYIGGIEHAVLHLLYARFYHKVLRDE  552
                SSWY+ R+  +++   + DE    +W PVD Y+GG EHAVLHLLYARF HKVL D 
Sbjct  493  QWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDL  552

Query  553  GLVSSDEPFTRLLTQGMVL-------------------KDGT---------------KMS  578
            G+V++ EPF +L+ QGM+L                   +DG+               KMS
Sbjct  553  GVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEELEQAPAKMS  612

Query  579  KSKGNTVDPQELVDRFGADTVRLFTMFAAPPDQSLEWSDSGVEGAYRFLRRLHGLV-RDH  637
            KS  N V+P+++V+++GADT+R++ MF +P D S+ WS+ G+EG+ +FL R+  L+   +
Sbjct  613  KSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKE  672

Query  638  VAAGPAPALDPQALSDTQRDLRRKVHETIAKASDDVGKRLTFNTAIAAVMELCNALGKAQ  697
            ++   + ALD             KV +   KA  +   ++ FNTAIA +M + NA  K +
Sbjct  673  ITEENSGALD-------------KVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKED  719

Query  698  DDSAAGRAVMQEGLEAAVLILAPITPHLCHHLWFQLGHTAPVVE-APWPEADKQALVRDE  756
                    +  +   + V ++AP++PHL ++LW  L  ++  +   PWP  D   LV ++
Sbjct  720  K-------LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVEND  772

Query  757  VELVVQVNGKLRGHVTLPadadqqqaqeaalaeHNVQRFVADKEIKKVVFVPGKLINVVA  816
            VE+VVQ++GK+++ + ++ D  +++ QE ALA+++VQ  +A+K+I KV+ VP KL+N+V 
Sbjct  773  VEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

Query  817  K  817
            K
Sbjct  833  K  833

1414) leuS in NC_015722


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  524 bits (1978),  Expect = 8e-150, Method: Compositional matrix adjust.
 Identities = 340/845 (41%), Positives = 550/845 (66%), Gaps = 30/845 (3%)

Query  6    YNHKKIEQKWQKIWSEKKVFEAQVDRSKPKKYILEMLPYPSGR-IHMGHLRNYTIGDVIA  64
            Y+H  IE KWQ +W+++  F +  D SKPK Y L+M+PYPSG  +H+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  65   RIQKSLGFNVLHQLGWDAFGLPAENAAMQNKVAPKQWTMENIASMKNQLLPMGFSYDWNR  124
            R++++ G NVLH +GWDAFGLPAE+ AM+    P + T ENIA+ K Q+ ++GFSYDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  125  EIATCSPDYYKHEQKFFIDFYNQGFAYQKEGIVNWDPIDQTVLANEQVI-DGRGWRSGAV  183
            E+ T  P+YYK  Q +F  +Y++G+AY+ E  VNW     T +ANE+V+ DG + R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  184  VKRKKLKQWFLKITDFAEDLLSGLEQLKGWPEKVRLMQTNWINKSEGAEVDFKT-DTGSK  242
            V RK ++QW LKIT +AE LL +LE++ +WPE ++ MQ NWI KS GA+V FK  DT+  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  IRIFTTRPETLFGATFIGVAFDHPLIENMDETPELSLFLEECKKISAPEDALEKA----E  298
            + +FTTRP+TLFGAT+  +A +H+L++ +  T++ +  + + K+ ++    L ++    E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAIT-TSDQAEAVADYKRQASLKSDLARTDLAKE  301

Query  299  KLGLDTGIKAIHPFDAAIKLPIFITNFVLSDYGTGAIFGCPAHDSRDHEFAVKYNLPIRQ  358
            K G+ TG  AI+P ++   +P+ I+++VL+ YGTGAI + PAHD RD EFA ++NL   +
Sbjct  302  KTGVWTGSYAINPVNGK-EMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNL---D  357

Query  359  VVKPLEDIEVDIMQAPFVDDGTMLNSDFLNDLSIAEAKKVIIKSLENNKIGVGKTTYRLK  418
            ++  LE+ +V+  +A+F +DG  +NSDFL++L  A A   ++  LE + +G  + TYRL+
Sbjct  358  IIPVLEGGNVE--EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  419  DWGISRQRYWGCPIPIIYCNNCGTLPVPEKDLPVVLPEDVQFDKPG---NPLDHHPTWKF  475
            DW +SRQRYWG PIPII  ++  + +VPE +LP+VLP   ++  +G   +PL +   W +
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDW-L  474

Query  476  VACPQCGKDALRETDTFDTFFESSWYFLRYCSPNSSSPFEKDE-IDYWGPVDQYIGGIEH  534
                + G  + RET+T      SSWY+LRY  P+++  +  +E +  W PVD Y+GG EH
Sbjct  475  EVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEH  534

Query  535  AVMHLLYARFFTRALKKLGYLNIDEPFTNLLTQGMINHETYKDQNNNWLYPEEVLKTQAG  594
            AV+HLLYARF  + L  LG +   EPF +L+ QGMI   +Y+D     +  + V K +++
Sbjct  535  AVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGS  594

Query  595  TIERANGAPVTVGRIEKMSKSKKNVVEPDRILDKYGADTIRLFVLSDSPPEKDLEWTEAG  654
             ++   G  +  +   KMSKS KNVV+PD ++++YGADT+R++ +  +P +  + W+E G
Sbjct  595  FFHVETGEELEQAP-AKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEG  653

Query  655  VEGCNKYLQRVAKLVFDTLDENKNGKDDEGVLSLI-HKTIQSVSTDFENFHFNKAIARLR  713
            +EG  K+L+RV +L+      +    ++ G L  + + T+++V+ + ++  FN AIA+L 
Sbjct  654  LEGSRKFLDRVYRLI----TTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLM  709

Query  714  ELTNALYSSDISSTIKKEGVKILTRLLNPIAPHLTEELWSTLGCGTMLAPY-PWPAPDLS  772
             + NA   ++    +  +  K + +L+ P+APHL EELW +L  +    +Y PWP+ D S
Sbjct  710  VFVNA---ANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDES  766

Query  773  LIKEDTVTIAIQTNGKLRSTIEVPKDTTQKEVERLSLELQNIRNFLNDKNIKKVIYIPNK  832
             + E+ V I +Q +GK+++ + V+KD ++ E++ ++L  ++++  + +K+I KVI +PNK
Sbjct  767  KLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNK  826

Query  833  IINIV  837
            ++NIV
Sbjct  827  LVNIV  831

1415) leuS in NC_016787


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  524 bits (1978),  Expect = 9e-150, Method: Compositional matrix adjust.
 Identities = 349/737 (48%), Positives = 508/737 (69%), Gaps = 57/737 (7%)

Query  228  LVYRSHSMVNWCPGLGTVLANEEVTADGRSERGNFPVFRKKLSQWMMRITAYSdrliddl  287
            L Y ++  VNW   LGT +ANEEV +DG SERG +PV RK + QWM++ITAY++RL++DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  288  dlldwpdKVKSMQRNWIGRSRGAEVDFD--ALGHTITVFTTRPDTLFGASYMVLAPEHEL  345
            + +DWP+ +K MQRNWIG+S GA+V F     +  +TVFTTRPDTLFGA+Y VLAPEH L
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  346  VDALVAAGTNSYEGIDPRWTFGQATPTEAVKAYRASIAAKSDLERQE-NKEKTGVYLGVN  404
            VDA+ +++                  +EAV  Y+   + KSDL R +  KEKTGV  G  
Sbjct  268  VDAITTSD-----------------QAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSY  310

Query  405  AVNPVNGESIPVFIGDYVLTGYGTGAIMAVPAHDTRDYEFATEFGLPIREVVAGGNIAEA  464
            A+NPVNG  +PV I+DYVL++YGTGAIMAVPAHD RD EFA +F L I  V+ GGN+ EA
Sbjct  311  AINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEA  370

Query  465  AYTESGAAVNSANDQGLDINGLDKQEAIARVIEWLVDKQKGSEKIQYKLRDWLFARQRYW  524
            A+TE G  +NS       ++GLDK  AIA+++EWL     G+E++ Y+LRDWLF+RQRYW
Sbjct  371  AFTEDGLHINSDF-----LDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYW  425

Query  525  GEPFPVVYDENGLAHALPESMLPVELPEVEDYKPVSFDPDDADSEPHPPLAKATEWTQVE  584
            GEP+P++  E+G + A+PES LP+ LP   D +P         +  ++PLA+ T+W +V 
Sbjct  426  GEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTDWLEVT  477

Query  585  LDLGDGLKKYTRDTNVMPQWAGSSWYQLRYIDPTNSEAFCDIENERYWTGPRSAEDSGGV  644
             +  DG+K   R+TN MPQWAGSSWY LRYIDP N+E + D E  + W           V
Sbjct  478  RE--DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLP---------V  525

Query  645  DLYVGGVEHAVLHLLYSRFWHKVLFDLGFVTSREPYRRLFNQGYIQAFAYTDSRGVYVPA  704
            D+YVGG EHAVLHLLY+RFWHKVL+DLG V ++EP+++LFNQG I + +Y DSRG  V++
Sbjct  526  DIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVAT  585

Query  705  EEVEEKDGKFYY--QGEEVNQEYGKMGKSLKNAVAPDDICRDFGADTLRVYEMAMGPLDT  762
            + VE +DG F+    GEE++Q  +KM+KSLKN V PDD+  ++GADTLRVYEM MGPLD+
Sbjct  586  DKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  763  SRPWSTKDVIGAHRFLQRLWRLVVSEDDGSIVVTDAALTDDDLKQLHRTIAGMRDDYEGL  822
            S +WS  ++ G+++FL+R+ RL+ + +   I   +++  D   K  + T+ ++ ++ + +
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLITTKE---ITEENSGALD---KVYNETVKAVTEQVDQM  699

Query  823  RINTVVAKAIEYVNYLTKAYGSTGAPRAAVAPLVIMVAAVAPHIAEELWKRL-GHNDTIT  881
            ++NT +A+ + +VN   K              +V ++A+ APH++EELW+ L +  ++I+
Sbjct  700  KFNTAIAQLMVFVNAANKE---DKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESIS  756

Query  882  FVPFPEYEDKWLVDDEVEMPVQINGKVRARIMVPADASQDQISEIALASDAVATHIEGKN  941
            +VP P Y++  LV+++VE+ VQI+GKV+A+++V+ D S++++ E+ALA++ V ++I GK+
Sbjct  757  YVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKD  816

Query  942  VIKKIVVPGRMVNLVVK  958
            +IK I VP ++VN+V+K
Sbjct  817  IIKVIAVPNKLVNIVIK  833


 Score =  140 bits (514),  Expect = 5e-34, Method: Compositional matrix adjust.
 Identities = 80/147 (55%), Positives = 104/147 (71%), Gaps = 10/147 (6%)

Query  27   IERSWQQYWIDNGTFNAPNPVGDLAVSGDKLPEDKLFVQDMFPYPSGAGLHVGHPLGYIA  86
            IE  WQ +W DN TF+          +G   +  K++  DMFPYPSGAGLHVGHP GY A
Sbjct  9    IEPKWQAFWADNHTFK----------TGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTA  58

Query  87   TDVFARFNRMLGKNVLHTLGYDAFGLPAEQYAIQTGTHPRTTTMANIANMQRQLGALGLG  146
            TD+++RF+R  G NVLH +G DAFGLPAEQYA++TG +P   T  NIAN +RQ+ ALG++
Sbjct  59   TDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFS  118

Query  147  HDPRRSVATTDPEFYKWTQWIFLQIFN  173
             D  R V TTDP++YKWTQWIF ++++
Sbjct  119  YDWDREVNTTDPNYYKWTQWIFTKLYE  145

1416) Nwat_0451 in NC_014315


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  523 bits (1975),  Expect = 1e-149, Method: Compositional matrix adjust.
 Identities = 365/860 (43%), Positives = 536/860 (63%), Gaps = 77/860 (8%)

Query  5    YRAAQIEAEAQAYWEQHQSFRVSEDPGKEKFYCLSMFPYPSGR-LHMGHVRNYTIGDVIS  63
            Y  + IE+  QA+W ++++F+ + D++K KFY L MFPYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMKGKNVLQPMGWDAFGLPAENAAIQNRVPPAQWTYENIGHMRKQLKRLGFAYDWSR  123
            R++R +G NVL+PMGWDAFGLPAE+ A++    PA+ T ENI++ ++Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCQPDYYHWEQWLFTKLFAKGLVYKKTALVNWDPVDQTVLANEQVI-DGRGWRSGAL  182
            E+ T +P+YY W QW+FTKL+ KGL Y     VNW     T +ANE+V+ DG + R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERREIPQWFLKITAYGEELLTSLDELTGWPEQVRAMQRNWIGRSEGVEVQFQVEGKE-A  241
            V R+ + QW LKITAY+E LL  L+E+ +WPE ++ MQRNWIG+S G +V F+V + +  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  242  LAVFTTRPDTLMGVTFVSVAAEHPLAREAAETNPALAAFLAQCQRTATSEAILE----TL  297
            ++VFTTRPDTL G T+  +A+EH+L    + ++ A A  +A+ +R A+  + L     + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEA--VADYKRQASLKSDLARTDLAK  300

Query  298  EKEGMDTGFKAIHPITGEAVPIWIANFVLMGYGTGAVMAVPAHDQRDYEFAKVYGLPIRQ  357
            EK G+ TG  AI+P+ G  +P+WIA++VL +YGTGA+MAVPAHD+RD EFAK + L I  
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  358  VIAPKDDQASCNLEQSAFVEKGLLINSGDFTGLDFDQAFTAIAEHLERGGKGQRRVNYRL  417
            V+       + N+E++AF E GL INS+ + GLD   A++ + E LE  G G+  V YRL
Sbjct  361  VL------EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRL  414

Query  418  RDWGVSRQRYWGAPIPIIH--CARCGAIpvpeedlpvvlpeRIQFDGV-RSPLKELPEFY  474
            RDW  SRQRYWG PIPIIH   +   A+P +E  L + +   I+  G   SPL ++ +  
Sbjct  415  RDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWL  474

Query  475  QTSCPQCGGQAKRETDTFDTFFESSWYYARYCCPDNNATMVDER-GDYWLPVDQYIGGIE  533
            + +  + G +++RET+T      SSWYY RY  P+N   + DE     WLPVD Y+GG E
Sbjct  475  EVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAE  533

Query  534  HAVLHLLYARFFHKVMRDMGLVRSDEPFTHLLTQGMVL-------------------KDG  574
            HAVLHLLYARF HKV+ D+G+V + EPF  L+ QGM+L                   +DG
Sbjct  534  HAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDG  593

Query  575  ---------------AKMSKSKGNTVDPQALIEHYGADTARLFIMFTAPPEQSLEWSESG  619
                           AKMSKS  N V+P+ ++E+YGADT R++ MF +P + S+ WSE G
Sbjct  594  SFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEG  653

Query  620  VEGAHRFLKRLWRTvavhvvevsgvvpvlkvNSLNTEQRLVRTKVHETITKASDDIGRRY  679
            +EG+++FL R+ R              ++  + +  E+     KV +   KA  +   + 
Sbjct  654  LEGSRKFLDRVYR--------------LITTKEITEENSGALDKVYNETVKAVTEQVDQM  699

Query  680  TFNTAIAAVMELMNALAKFEGLSPQGQAVRQEALEAVVLLLSPITPHICHRLWRELGHRE  739
             FNTAIA +M ++NA  K + L +       +   + V L++P++PH+ + LW+ L    
Sbjct  700  KFNTAIAQLMVFVNAANKEDKLFS-------DYAKGFVQLIAPFAPHLGEELWQALTASG  752

Query  740  AIID-VPWPEADPDALAKERIELVVQVNGKRRGQITVAAQAPREEIEGQAQAEPNVQRFI  798
              I  VPWP  D   L  + +E+VVQ++GK ++++ VA + +REE++  A A+ +VQ  I
Sbjct  753  ESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEI  812

Query  799  EGKTVQKVIIVPNRLVNLVV  818
             GK + KVI VPN+LVN+V+
Sbjct  813  AGKDIIKVIAVPNKLVNIVI  832

1417) leuS in NC_016783


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  523 bits (1975),  Expect = 2e-149, Method: Compositional matrix adjust.
 Identities = 350/737 (48%), Positives = 507/737 (69%), Gaps = 57/737 (7%)

Query  228  LVYRSHSMVNWCPGLGTVLANEEVTADGRSERGNFPVFRKKLSQWMMRITAYSdrliddl  287
            L Y ++  VNW   LGT +ANEEV +DG SERG +PV RK + QWM++ITAY++RL++DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  288  dlldwpdKVKSMQRNWIGRSRGAEVDFD--ALGHTITVFTTRPDTLFGASYMVLAPEHEL  345
            + +DWP+ +K MQRNWIG+S GA+V F     +  +TVFTTRPDTLFGA+Y VLAPEH L
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  346  VDALVTAGTNSYEGIDPRWTFGQATPAEAVKAYRASIAAKSDLERQE-NKEKTGVYLGVN  404
            VDA+ T++                  AEAV  Y+   + KSDL R +  KEKTGV  G  
Sbjct  268  VDAITTSD-----------------QAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSY  310

Query  405  AVNPVNGESIPVFIGDYVLTGYGTGAIMAVPAHDTRDYEFATEFGLPIREVVAGGNIAEA  464
            A+NPVNG  +PV I+DYVL++YGTGAIMAVPAHD RD EFA +F L I  V+ GGN+ EA
Sbjct  311  AINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEA  370

Query  465  AYTESGAAVNSANDQGLDINGLDKQEAIAQVIEWLVDKQKGSEKIQYKLRDWLFARQRYW  524
            A+TE G  +NS       ++GLDK  AIA+++EWL     G+E++ Y+LRDWLF+RQRYW
Sbjct  371  AFTEDGLHINSDF-----LDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYW  425

Query  525  GEPFPVVYDENGLAHALPESMLPVELPEVEDYKPVSFDPDDADSEPHPPLAKATEWTQVE  584
            GEP+P++  E+G + A+PES LP+ LP   D +P         +  ++PLA+ T+W +V 
Sbjct  426  GEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTDWLEVT  477

Query  585  LDLGDGLKKYTRDTNVMPQWAGSSWYQLRYIDPTNSEAFCDIENERYWTGPRSAEDSGGV  644
             +  DG+K   R+TN MPQWAGSSWY LRYIDP N+E + D E  + W           V
Sbjct  478  RE--DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLP---------V  525

Query  645  DLYVGGVEHAVLHLLYSRFWHKVLFDLGFVTSREPYRRLFNQGYIQAFAYTDSRGVYVPA  704
            D+YVGG EHAVLHLLY+RFWHKVL+DLG V ++EP+++LFNQG I + +Y DSRG  V++
Sbjct  526  DIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVAT  585

Query  705  EEVEEKDGKFYY--QGEEVNQEYGKMGKSLKNAVAPDDICRDFGADTLRVYEMAMGPLDT  762
            + VE +DG F+    GEE++Q  +KM+KSLKN V PDD+  ++GADTLRVYEM MGPLD+
Sbjct  586  DKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  763  SRPWSTKDVIGAHRFLQRLWRLVVSEDDGSIVVTDAALTDDDLKQLHRTIAGMRDDYEGL  822
            S +WS  ++ G+++FL+R+ RL+ + +     +T+      D K  + T+ ++ ++ + +
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLITTKE-----ITEENSGALD-KVYNETVKAVTEQVDQM  699

Query  823  RINTVVAKAIEYVNYLTKAYGSTGAPRAAVEPLVIMVAAVAPHIAEELWKRL-GHNDTIT  881
            ++NT +A+ + +VN   K              +V ++A+ APH++EELW+ L +  ++I+
Sbjct  700  KFNTAIAQLMVFVNAANKE---DKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESIS  756

Query  882  FVPFPEYEDKWLVDDEVEMPVQINGKVRARIMVPADATQEQISEIALASDAVTTHIEGKN  941
            +VP P Y++  LV+++VE+ VQI+GKV+A+++V+ D ++E++ E+ALA++ V ++I GK+
Sbjct  757  YVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKD  816

Query  942  VVKKIVVPGRMVNLVVK  958
            ++K I VP ++VN+V+K
Sbjct  817  IIKVIAVPNKLVNIVIK  833


 Score =  140 bits (513),  Expect = 6e-34, Method: Compositional matrix adjust.
 Identities = 80/147 (55%), Positives = 104/147 (71%), Gaps = 10/147 (6%)

Query  27   IERSWQQYWIDNGTFNAPNPVGDLAVSGDKLPEDKLFVQDMFPYPSGAGLHVGHPLGYIA  86
            IE  WQ +W DN TF+          +G   +  K++  DMFPYPSGAGLHVGHP GY A
Sbjct  9    IEPKWQAFWADNHTFK----------TGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTA  58

Query  87   TDVFARFNRMLGKNVLHTLGYDAFGLPAEQYAIQTGTHPRTTTMANIANMQRQLGALGLG  146
            TD+++RF+R  G NVLH +G DAFGLPAEQYA++TG +P   T  NIAN +RQ+ ALG++
Sbjct  59   TDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFS  118

Query  147  HDPRRSVATTDPEFYKWTQWIFLQIFN  173
             D  R V TTDP++YKWTQWIF ++++
Sbjct  119  YDWDREVNTTDPNYYKWTQWIFTKLYE  145

1418) leuS in NC_016789


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  523 bits (1974),  Expect = 2e-149, Method: Compositional matrix adjust.
 Identities = 349/737 (48%), Positives = 508/737 (69%), Gaps = 57/737 (7%)

Query  228  LVYRSHSMVNWCPGLGTVLANEEVTADGRSERGNFPVFRKKLSQWMMRITAYSdrliddl  287
            L Y ++  VNW   LGT +ANEEV +DG SERG +PV RK + QWM++ITAY++RL++DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  288  dlldwpdKVKSMQRNWIGRSRGAEVDFD--ALGHTITVFTTRPDTLFGASYMVLAPEHEL  345
            + +DWP+ +K MQRNWIG+S GA+V F     +  +TVFTTRPDTLFGA+Y VLAPEH L
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  346  VDALVAAGTNSYEGIDPRWTFGQATPAEAVKAYRASIAAKSDLERQE-NKEKTGVYLGVN  404
            VDA+ +++                  AEAV  Y+   + KSDL R +  KEKTGV  G  
Sbjct  268  VDAITTSD-----------------QAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSY  310

Query  405  AVNPVNGESIPVFIGDYVLTGYGTGAIMAVPAHDTRDYEFATEFDLPIREVVAGGNIAEA  464
            A+NPVNG  +PV I+DYVL++YGTGAIMAVPAHD RD EFA +F+L I  V+ GGN+ EA
Sbjct  311  AINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEA  370

Query  465  AYTESGAAVNSANDQGLDINGLDKQEAIAQVIEWLVDKQKGSEKIQYKLRDWLFARQRYW  524
            A+TE G  +NS       ++GLDK  AIA+++EWL     G+E++ Y+LRDWLF+RQRYW
Sbjct  371  AFTEDGLHINSDF-----LDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYW  425

Query  525  GEPFPVVYDENGLAHALPESMLPVELPEVEDYKPVSFDPDDADSEPHPPLAKATEWTQVE  584
            GEP+P++  E+G + A+PES LP+ LP   D +P         +  ++PLA+ T+W +V 
Sbjct  426  GEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTDWLEVT  477

Query  585  LDLGDGLKKYTRDTNVMPQWAGSSWYQLRYIDPTNSEAFCDIENERYWTGPRSAEDSGGV  644
             +  DG+K   R+TN MPQWAGSSWY LRYIDP N+E + D E  + W           V
Sbjct  478  RE--DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLP---------V  525

Query  645  DLYVGGVEHAVLHLLYSRFWHKVLFDLGFVTSREPYRRLFNQGYIQAFAYTDSRGVYVPA  704
            D+YVGG EHAVLHLLY+RFWHKVL+DLG V ++EP+++LFNQG I + +Y DSRG  V++
Sbjct  526  DIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVAT  585

Query  705  EEVEEKDGKFYY--QGEEVNQEYGKMGKSLKNAVAPDDICRDFGADTLRVYEMAMGPLDT  762
            + VE +DG F+    GEE++Q  +KM+KSLKN V PDD+  ++GADTLRVYEM MGPLD+
Sbjct  586  DKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  763  SRPWSTKDVIGAHRFLQRLWRLVVSEDDGSIVVTDAALTDDDLKQLHRTIAGMRDDYEGL  822
            S +WS  ++ G+++FL+R+ RL+ + +     +T+      D K  + T+ ++ ++ + +
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLITTKE-----ITEENSGALD-KVYNETVKAVTEQVDQM  699

Query  823  RINTVVAKAIEYVNYLTKAYGSTGAPRAAVEPLVIMVAAVAPHIAEELWKRL-GHNDTIT  881
            ++NT +A+ + +VN   K              +V ++A+ APH++EELW+ L +  ++I+
Sbjct  700  KFNTAIAQLMVFVNAANKE---DKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESIS  756

Query  882  FVPFPEYEDKWLVDDEVEMPVQINGKVRARIMVPADASQDQISEIALASDAVTTHIEGKN  941
            +VP P Y++  LV+++VE+ VQI+GKV+A+++V+ D S++++ E+ALA++ V ++I GK+
Sbjct  757  YVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKD  816

Query  942  VVKKIVVPGRMVNLVVK  958
            ++K I VP ++VN+V+K
Sbjct  817  IIKVIAVPNKLVNIVIK  833


 Score =  140 bits (513),  Expect = 6e-34, Method: Compositional matrix adjust.
 Identities = 80/147 (55%), Positives = 104/147 (71%), Gaps = 10/147 (6%)

Query  27   IERSWQQYWIDNGTFNAPNPVGDLAVSGDKLPEDKLFVQDMFPYPSGAGLHVGHPLGYIA  86
            IE  WQ +W DN TF+          +G   +  K++  DMFPYPSGAGLHVGHP GY A
Sbjct  9    IEPKWQAFWADNHTFK----------TGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTA  58

Query  87   TDVFARFNRMLGKNVLHTLGYDAFGLPAEQYAIQTGTHPRTTTMANIANMQRQLGALGLG  146
            TD+++RF+R  G NVLH +G DAFGLPAEQYA++TG +P   T  NIAN +RQ+ ALG++
Sbjct  59   TDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFS  118

Query  147  HDPRRSVATTDPEFYKWTQWIFLQIFN  173
             D  R V TTDP++YKWTQWIF ++++
Sbjct  119  YDWDREVNTTDPNYYKWTQWIFTKLYE  145

1419) leuS in NC_016785


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  523 bits (1975),  Expect = 2e-149, Method: Compositional matrix adjust.
 Identities = 347/740 (47%), Positives = 510/740 (69%), Gaps = 63/740 (8%)

Query  228  LVYRSHSMVNWCPGLGTVLANEEVTADGRSERGNFPVFRKKLSQWMMRITAYSdrliddl  287
            L Y ++  VNW   LGT +ANEEV +DG SERG +PV RK + QWM++ITAY++RL++DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  288  dlldwpdKVKSMQRNWIGRSRGAEVDFD--ALGHTITVFTTRPDTLFGASYMVLAPEHEL  345
            + +DWP+ +K MQRNWIG+S GA+V F     +  +TVFTTRPDTLFGA+Y VLAPEH L
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  346  VDALVAAGTNSYEGIDPRWTFGQATPAEAVKAYRASIAAKSDLERQE-NKEKTGVYLGVN  404
            VDA+ +++                  AEAV  Y+   + KSDL R +  KEKTGV  G  
Sbjct  268  VDAITTSD-----------------QAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSY  310

Query  405  AVNPVNGESIPVFIGDYVLTGYGTGAIMAVPAHDTRDYEFATEFGLPIREVVAGGNIAEE  464
            A+NPVNG  +PV I+DYVL++YGTGAIMAVPAHD RD EFA +F L I  V+ GGN+ E 
Sbjct  311  AINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEA  370

Query  465  AYTESGAAVNSANDQGLDINGLDKQEAIARVIEWLVDKQKGSEKIQYKLRDWLFARQRYW  524
            A+TE G  +NS       ++GLDK  AIA+++EWL     G+E++ Y+LRDWLF+RQRYW
Sbjct  371  AFTEDGLHINSDF-----LDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYW  425

Query  525  GEPFPVVYDENGLAHALPESMLPVELPEVEDYKPVSFDPDDADSEPHPPLAKATEWTQVE  584
            GEP+P++  E+G + A+PES LP+ LP   D +P         +  ++PLA+ T+W +V 
Sbjct  426  GEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTDWLEVT  477

Query  585  LDLGDGLKKYTRDTNVMPQWAGSSWYQLRYIDPTNSEAFCDIENERYWTGPRSAEDSGGV  644
             +  DG+K   R+TN MPQWAGSSWY LRYIDP N+E + D E  + W           V
Sbjct  478  RE--DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLP---------V  525

Query  645  DLYVGGVEHAVLHLLYSRFWHKVLFDLGFVTSREPYRRLFNQGYIQAFAYTDSRGVYVPA  704
            D+YVGG EHAVLHLLY+RFWHKVL+DLG V ++EP+++LFNQG I + +Y DSRG  V++
Sbjct  526  DIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVAT  585

Query  705  EEVEEKDGKFYY--QGEEVNQEYGKMGKSLKNAVAPDDICRDFGADTLRVYEMAMGPLDT  762
            + VE +DG F+    GEE++Q  +KM+KSLKN V PDD+  ++GADTLRVYEM MGPLD+
Sbjct  586  DKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  763  SRPWSTKDVIGAHRFLQRLWRLVVSEDDGSIVVTDAALTDDDLKQLHRTIAGMRDDYENL  822
            S +WS  ++ G+++FL+R+ RL+ + +     +T+      D K  + T+ ++ ++ +++
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLITTKE-----ITEENSGALD-KVYNETVKAVTEQVDQM  699

Query  823  RINTVVAKAIEYVNYLTKA---YGSTGAPRAAVEPLVIMVAAVAPHIAEELWKRL-GHND  878
            ++NT +A+ + +VN   K    ++  +        +V ++A+ APH++EELW+ L +  +
Sbjct  700  KFNTAIAQLMVFVNAANKEDKLFSDYA------KGFVQLIAPFAPHLGEELWQALTASGE  753

Query  879  TITFVPFPEYEDKWLVDDEVEMPVQINGKVRARIMVPADATQDQISEIALASDAVTTHIE  938
            +I++VP P Y++  LV+++VE+ VQI+GKV+A+++V+ D +++++ E+ALA++ V ++I 
Sbjct  754  SISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIA  813

Query  939  GKNVVKKIVVPGRMVNLVVK  958
            GK+++K I VP ++VN+V+K
Sbjct  814  GKDIIKVIAVPNKLVNIVIK  833


 Score =  140 bits (513),  Expect = 6e-34, Method: Compositional matrix adjust.
 Identities = 80/147 (55%), Positives = 104/147 (71%), Gaps = 10/147 (6%)

Query  27   IERSWQQYWIDNGTFNAPNPVGDLAVSGDKLPEDKLFVQDMFPYPSGAGLHVGHPLGYIA  86
            IE  WQ +W DN TF+          +G   +  K++  DMFPYPSGAGLHVGHP GY A
Sbjct  9    IEPKWQAFWADNHTFK----------TGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTA  58

Query  87   TDVFARFNRMLGKNVLHTLGYDAFGLPAEQYAIQTGTHPRTTTMANIANMQRQLGALGLG  146
            TD+++RF+R  G NVLH +G DAFGLPAEQYA++TG +P   T  NIAN +RQ+ ALG++
Sbjct  59   TDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFS  118

Query  147  HDPRRSVATTDPEFYKWTQWIFLQIFN  173
             D  R V TTDP++YKWTQWIF ++++
Sbjct  119  YDWDREVNTTDPNYYKWTQWIFTKLYE  145

1420) leuS in NC_012997


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  523 bits (1974),  Expect = 2e-149, Method: Compositional matrix adjust.
 Identities = 356/863 (42%), Positives = 544/863 (64%), Gaps = 81/863 (9%)

Query  19   LYNPSEIEQQAQQYWESHKSFEVSEDTSKEKFYCLAMFPYPSGR-LHMGHVRNYTITDVI  77
            +Y+ + IE + Q +W  + +F  + D+SK KFY L MFPYPSG  LH+GH   YT TD++
Sbjct  3    FYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDIL  62

Query  78   ARFQRMQGKNVLHPMGWDAFGLPAENAAIKNNTAPAKWTYANTDYMRSQLKELGFGFDWT  137
            +RF+R QG NVLHPMGWDAFGLPAE+ A+     PA  T  N    + Q++ LGF++DW 
Sbjct  63   SRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWD  122

Query  138  REVTTCKPDYYRWEQWFFTRLYEKGLAYKKVSAVNWCPNDQTVLANEQVV-EGCCWRCDT  196
            REV T  P+YY+W QW+FT+LYEKGLAY    +VNW  +  T +ANE+V+ +G   R + 
Sbjct  123  REVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGY  182

Query  197  PVERKEIPQWFIRITDYAEELLKDLDKLPHWPEQVRTMQKNWIGKSKGVQMSFDLSAPIA  256
            PV RK + QW ++IT YAE LL DL+ + +WPE ++ MQ+NWIGKS G +++F +     
Sbjct  183  PVVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDT--  239

Query  257  GHDHFEVYTTRPDTTMGITYVTLAAEHPI--ALAVAEHNPALAEFIQECKVQSVAEADMA  314
             + +F V+TTRPDT  G TY  LA+EH++  A++ +++  A+A++ ++  ++S       
Sbjct  240  -DKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDL  298

Query  315  SMEKKGMDTGLKALHPITREEVPVWVGNYVLMDYGSGAVMAVPGHDQRDWEFARKYDLPI  374
            + EK G+ TG  A++P+   E+PVW+++YVL  YG+GA+MAVP+HD+RDWEFA++++L I
Sbjct  299  AKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDI  358

Query  375  KQVVASKDGEEIDLNTAAFVEKGILVNSGEYDGLDFNAAFEALSQTLVAAGKGRVTTNYR  434
              V+ + + EE     AAF E G+ +NS+  DGLD  +A+  + + L A G G     YR
Sbjct  359  IPVLEGGNVEE-----AAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYR  413

Query  435  LRDWGVSRQRYWGAPIPIFNLPDGGEIPVPAHKLPILLP--EDVVMDGV-QSPIKADVSW  491
            LRDW  SRQRYWG PIPI++  DG   +VP   LP++LP   D+   G  +SP+     W
Sbjct  414  LRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDW  473

Query  492  ----KKDELDGQAVERETDTFDTFMESSWYYARYAGP-SSESMIDSDKANYWLPVDQYVG  546
                + D + G+   RET+T      SSWYY RY +P ++E + D +  + WLPVD YVG
Sbjct  474  LEVTREDGVKGR---RETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVG  530

Query  547  GIEHAILHLLYARFFHKLMRDEGLVACDEPFERLLCQGMVL-------------------  587
            G EHA+LHLLYARF HK++ D G+V+  EPF++L+ QGM+L                   
Sbjct  531  GAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEK  590

Query  588  KDGT---------------KMSKSKGNTVDPAELIGQYGADTVRLFTMFAAPPEQSLEWT  632
            +DG+               KMSKS  N V+P +++ QYGADT+R++ MF +P + S+ W+
Sbjct  591  RDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWS  650

Query  633  DSGVEGAFRFLKKLWKTVQT-HLAAGEPGELNPAELNDTQKDLRRKTHETIAKVTDDYGR  691
            + G+EG+ +FL ++ + + T +++  ++G L+            +  +ET+  VT++ ++
Sbjct  651  EEGLEGSRKFLDRVYRLITTKEITEENSGALD------------KVYNETVKAVTEQVDQ  698

Query  692  RQTFNTAIAAVMELLNEVGRNADRANEQGLSVEREALEAAVQVLAPIVPHICHELWLAL-  750
             + FNTAIA +M ++N   ++    ++ +         + VQ++AP+ PH+ +ELW AL 
Sbjct  699  MK-FNTAIAQLMVFVNAANKEDKLFSDYA--------KGFVQLIAPFAPHLGEELWQALT  749

Query  751  GHSEPVLDVTWPAADEEAMVKSSITLVAQVNGKVRakleapadadkdaleklaladpNVQ  810
            + +E++  V WP+ DE  +V + + +V Q++GKV+AKL  + D  ++ L+ +ALA+ +VQ
Sbjct  750  ASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQ  809

Query  811  KFIADKMIRKIIVVPGKLVNIVV  833
              IA+K I K+I VP KLVNIV+
Sbjct  810  AEIAGKDIIKVIAVPNKLVNIVI  832

1421) AnaeK_2819 in NC_011145


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  523 bits (1975),  Expect = 2e-149, Method: Compositional matrix adjust.
 Identities = 352/861 (41%), Positives = 543/861 (64%), Gaps = 68/861 (7%)

Query  7    YEPQSIEPRWQRRWEEAGAFKAGRRPDADTRYVLEMFPYPSGA-MHMGHARVYTIGDALA  65
            Y+  +IEP+WQ  W +  +FK+G  +     Y L+MFPYPSGA +H+GH+  YT  D L+
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  66   RHLRMRGFDVLHPIGFDALGLPAENAAIKDGRHPAERTRENVVSFRAEMKRLGYSFDWDR  125
            R  R +G +VLHP+G DA+GLPAE+ A+  G +PAE T EN+ +F+ +++ LG+S+DWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  126  ELVTADASYYRWNQWFFLKMLEKGIAYRRQGKVNWCTGCQTVIANEQVVDDNRCERCGSP  185
            E+ T+D++YY+W QW+F K+ EKG+AY  +  VNW     T IANE+V+ D   ER G P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  186  VVEKIHPEWAFRITAYAqqlldgldglKDWPDRVTTMQRNWIGKSEGAEVDFALAAGGAA  245
            VV K   +W ++ITAYA++LL++L+ + DWP+ +  MQRNWIGKS GA+V F +   +  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  246  VKVFTTRVDTIYGCTYVVLAPEHPLVAQVTAPERRAEVDAFVARMRKTDAVERTGEGAPK  305
              VFTTR DT++G TY VLAPEH+LV  +T++++   V  +  +      + RT+ +  K
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEK  302

Query  306  EGVFTGAFAVNPFTGEQVPIWIANFVLAEYGTGAVMSVPAHDQRDFEFARKYGLPVRVVI  365
             GV TG++A+NP  G ++P+WIA++VLA YGTGA+M+VPAHD+RD EFA+++ L +  V 
Sbjct  303  TGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV-  361

Query  366  QPAHGARLPAGDALDRAATEDGVLEGSGPFTGLASAEARSRMSAHAAERGFGQGTVRWHL  425
                   L +G+  + A TEDG+   S+ + GL  A A ++M       G G+  V  +L
Sbjct  362  -------LEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRL  414

Query  426  RDWGFSRQRYWGTPIPIIYCDEHGMVPVPEQDLPVVLPAEAII--TGTGEPPLAKVASFV  483
            RDW FSRQRYWG PIPII  ++    +VPE +LP+VLP    I  +GTGE+PLA+V+  +
Sbjct  415  RDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWL  474

Query  484  NTTCPRCGKPARREVETMDTFVDSSWYYARYLSPKDEARPFDPEAARRWLPVDVYVGGPE  543
            + T     K +RRE +TM    +SSWYY RY+ P +  +  D E  ++WLPVD+YVGG+E
Sbjct  475  EVTREDGVK-GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAE  533

Query  544  HAVMHLLYFRFWHRVMHELGLVHEDEPVRRLVTQGIVNGP---DGR--------------  586
            HAV+HLLY RFWH+V+ +LG+V   EP ++L  QG++ G    D+R              
Sbjct  534  HAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDG  593

Query  587  ----------------KMSKRWGNVVAPGGMVSRFGADTVRMFMLFAAPPEKDIDWSDEQ  630
                            KMSK   NVV P+++V ++GADT+R++ +F +P +  I WS+E 
Sbjct  594  SFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEG  653

Query  631  VDGLFRFLARVWRIYFARQACFDaseaalaqaagealelrrrTHRTIKRVTEGLEADLKF  690
            ++G  +FL RV R+  +++               ++  L +  + T+K VTE ++ ++KF
Sbjct  654  LEGSRKFLDRVYRLITTKEIT-----------EENSGALDKVYNETVKAVTEQVD-QMKF  701

Query  691  NTSIAALMELVNALYAFEPASEPDRaavreallalatllapfaPHVAEELWHEVMGPVAR  750
            NT+IA LM        F  A++ +     +   ++  L+APFAPH++EELW+ + ++   
Sbjct  702  NTAIAQLM-------VFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGES  754

Query  751  ERLVADAPWPPFDPALIVADTVTIAVQVNGKLRGEVQapaaageaevralaeaDEKVKVH  810
               ++  PWP++D + +V + V I VQ++GK+++ +  +   +  E++ +A A+EKV+ +
Sbjct  755  ---ISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAE  811

Query  811  LAGKTVRKVVFVPKRLVNFVV  831
            +AGK + KV+ VP++LVN+V+
Sbjct  812  IAGKDIIKVIAVPNKLVNIVI  832

1422) leuS in NC_016514


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  523 bits (1974),  Expect = 2e-149, Method: Compositional matrix adjust.
 Identities = 352/865 (41%), Positives = 549/865 (64%), Gaps = 46/865 (5%)

Query  57   YRPEEIESKVQQHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIA  115
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  116  RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSR  175
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  176  ELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  234
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  235  VERKEIPQWFIKITAYAdellndldnldHWPDTVKTMQRNWIGRSEGVEITFNVENDDRT  294
            V RK + QW +KITAYA E L +  +  +WP+++K MQRNWIG+S G ++TF+V + D+ 
Sbjct  184  VVRKPMRQWMLKITAYA-ERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  295  LTVYTTRPDTFMGATYLAVAAGHPLAQ--KAAENNPELAAFIDECR-NTKVAEADMATME  351
            +TV+TTRPDT+ GATY  +A+ H+L +   ++++   +A +  +   ++ +A +D+A  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  352  KKGVDTGFKAIHPLTGEAIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFATKYGLTIKPV  411
            K GV TG  AI+P+ G  +PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L I PV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  412  ILAADGSEPDLSAQALTEKGTLFNSGEFSGLSFEDGFNAIADKLASLGVGERKVNYRLRD  471
            + +++  E+ ++ ++L  ++ +++     GL    ++  + + L + GVG+ +V YRLRD
Sbjct  362  LEGGNVEEAAFTEDGLHINSDFLD-----GLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  472  WGVSRQRYWGAPIPMVTLEDGTVMPTPEDQLPVILP--EDVIMDGIT-SPIKADPEWAKT  528
            W  SRQRYWG PIP++  EDGT  + PE +LP++LP   D+   G   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  529  T-VNGQPALRETDTFDTFMESSWYYARYTCPQYQEGMLDSDAANYWLPVDIYIGGIEHAI  587
            T  +G  + RET+T      SSWYY RY  P+  E + D +  + WLPVDIY+GG EHA+
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  588  MHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGANGERNWVSPVDAIVER  647
            +HLLY RF HK++ D G+V + EP ++L+ QGM+L+ +  Y ++ G    + + D +  R
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS--YRDSRGA---LVATDKVEKR  591

Query  648  DEKGRIVKAKDAEGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMT  707
            D  G +     +E  E    + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D +
Sbjct  592  D--GSFFHVETGEELE---QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  708  LEWQESGVEGANRFLKRVWKLVYEHTSQGDAPAVNVAALTEDQQALRRDVHKTIAKVTDD  767
            + W E G+EG+ +FL RV +L+          + +++   E+  AL +  + T+  VT++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLI---------TTKEITE--ENSGALDKVYNETVKAVTEQ  695

Query  768  IGRRQTFNTAIAAIMELMNKLAKAPQDGEQDRALMREALLAVVRMLNPFTPHVSFTLWQE  827
            +++ + FNTAIA +M ++N        ++++  L  +   + V+++ PF+PH++  LWQ 
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  828  LKGEGD-IDNAPWPVADESAMVENTTLVVVQVNGKVRGKITVAVDATEEQVRERAGQEHL  886
            L + G+ I   PWP  DES +VEN   +VVQ++GKV++K+ VA D + E+++E A  ++ 
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  887  VAKYLEGVTVRKVIYVPGKLLNLVV  911
            V   + G  + KVI VP KL+N+V+
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVI  832

1423) OOM_1545 in NC_017909


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  523 bits (1974),  Expect = 2e-149, Method: Compositional matrix adjust.
 Identities = 348/859 (41%), Positives = 548/859 (64%), Gaps = 72/859 (8%)

Query  1    MSEYNFTQIEQQAQKYWRENNSFKAVEDKNKEKFYCLSMLPYPSGT-LHMGHVRNYTIGD  59
            M+ Y+ T IE + Q +W +N++FK+  D +K KFY L M+PYPSG+ LH+GH   YT  D
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  60   VIARYQKMQGKNVLHPMGWDAFGLPAENAAIKHKKSPYKWTKSNIAYMKSQLDSLGFSFD  119
            +++R+++ QG NVLHPMGWDAFGLPAE+ A+   + P   T  NIA  K Q+++LGFS+D
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  120  WSREVVTCDENYYEWEQWFFIQLYKKGLAYRKNSVVNW-DPIDQTVLANEQVVDGRGWRS  178
            W REV T D NYY W QW+F +LY KGLAY  +  VNW + ++ ++  +E + DG + R+
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  179  GALIEKKEIPQWFLKITDYADELLKDINQLDGWPEAVKTMQTNWIGKSKGLTIKFKIENS  238
            G  + +K + QW LKIT YA+ LL D++++D WPE++K MQ NWIGKS G  + FK+ ++
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDT  239

Query  239  DQEIEVFTTCPDTLMGVSYLGIAPKHPLALEEAKTNSQLKSFIEECKKISTMEADLA---  295
            D+++ VFTT PDTL G +Y  +AP H+L   +A T S+    + + K+ +++ +DLA   
Sbjct  240  DKDFTVFTTRPDTLFGATYAVLAPEHALV--DAITTSDQAEAVADYKRQASLKSDLARTD  297

Query  296  -TQEKKGFKTSIKVTHPISGESIDVWVANFVLMGYGSGAVMSVPAHDQRDWEFAQKYNIA  354
             ++EK G  T+    +P++G  + VW+A++VL +YG+GA+M+VPAHD+RDWEFA+++N+ 
Sbjct  298  LAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLD  357

Query  355  LKQVIKPSDNKSKLDLDKEAFTEKGILINSGEFDGLNFKTAYQAIKKYLFDNDKGYETTN  414
            +  V+  +      +++  AFTE G+ INS+ +DGL+  +A   +   L  ++ G E   
Sbjct  358  IIPVLEGG------NVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVT  411

Query  415  FRIHDWGISRQRYWGCPIPMIHCNDCGLVPEKEENLPVKLPTNVTLTEAG---SPLKEMS  471
            +R++DW +SRQRYWG PIP+IH +D    +  E +LP+ LP    +  +G   SPL +++
Sbjct  412  YRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVT  471

Query  472  EFLNVACPHCGKPATRetdtfdtffessWYYARYTCPTADKMLSEEA--NYWLPVDKYIG  529
            + L+V+  +  K + RET+T      SSWYY RY  P     L++E   + WLPVD Y+G
Sbjct  472  DWLEVTREDGVK-GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVG  530

Query  530  GIEHAIMHLLYARFFHKLMRDQGLVSSDEPFKNLLTQGMVL-------------------  570
            G EHA++HLLYARF HK++ D G+V++ EPF++L+ QGM+L                   
Sbjct  531  GAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEK  590

Query  571  KDG---------------AKMSKSKGNTVDPQELIDKYGADTVRLFSMFAAPPEQSLEWS  615
            +DG               AKMSKS  N V+P++++++YGADT+R++ MF +P + S+ WS
Sbjct  591  RDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWS  650

Query  616  ETGVDGANKFLRKVYNYAYTNKEILAKNITIDLTKLSKNDKKARYEIYANFKQAIFDFDK  675
            E G++G+ KFL +VY    T KEI + + +  L K+ ++  KA   +  +  Q  F+   
Sbjct  651  EEGLEGSRKFLDRVYRLI-TTKEI-TEENSGALDKVYNETVKA---VTEQVDQMKFNTAI  705

Query  676  SQFNTVVSACMKILNTLNNYDNLSDSVKSEGFSILLRILSPFTPHICHYLWQKI-GLGED  734
            +Q+   V+A  K  + +++Y +        GF   +++++PF+PH+ + LWQ + + GE 
Sbjct  706  AQLMVFVNAANKEDKLFSDYAK--------GF---VQLIAPFAPHLGEELWQALTASGES  754

Query  735  ILHTQFPTVDNKALEKDDFLLVVQINGKVKAKLELDGSLTKEQVEQEVLDDEHIKTFIED  794
            I     P+ D+  L  +D  +VVQI+GKVKAKL +   L++E++++  L +E +++ I +
Sbjct  755  ISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAG  814

Query  795  KQIIKVIYVPQKLINIVVK  813
            K+IIKVI VP+KL+NIV+K
Sbjct  815  KDIIKVIAVPNKLVNIVIK  833

1424) leuS in NC_016788


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  523 bits (1972),  Expect = 3e-149, Method: Compositional matrix adjust.
 Identities = 349/737 (48%), Positives = 506/737 (69%), Gaps = 57/737 (7%)

Query  228  LVYRSHSMVNWCPGLGTVLANEEVTADGRSERGNFPVFRKKLSQWMMRITAYSdrliddl  287
            L Y ++  VNW   LGT +ANEEV +DG SERG +PV RK + QWM++ITAY++RL++DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  288  dlldwpdKVKSMQRNWIGRSRGAEVDFD--ALGHTITVFTTRPDTLFGASYMVLAPEHEL  345
            + +DWP+ +K MQRNWIG+S GA+V F     +  +TVFTTRPDTLFGA+Y VLAPEH L
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  346  VDALVAAGTNSYEGIDPRWTFGQATPAEAVKAYRASIAAKSDLERQE-NKEKTGVYLGVN  404
            VDA+ +++                  AEAV  Y+   + KSDL R +  KEKTGV  G  
Sbjct  268  VDAITTSD-----------------QAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSY  310

Query  405  AVNPVNGESIPVFIGDYVLTGYGTGAIMAVPAHDTRDYEFATEFGLPIREVVAGGNIAEE  464
            A+NPVNG  +PV I+DYVL++YGTGAIMAVPAHD RD EFA +F L I  V+ GGN+ E 
Sbjct  311  AINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEA  370

Query  465  AYTESGAAVNSANDQGLDINGLDKQEAIAQVIEWLVDKQKGSEKIQYKLRDWLFARQRYW  524
            A+TE G  +NS       ++GLDK  AIA+++EWL     G+E++ Y+LRDWLF+RQRYW
Sbjct  371  AFTEDGLHINSDF-----LDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYW  425

Query  525  GEPFPVVYDENGLAHALPESMLPVELPEVEDYKPVSFDPDDADSEPHPPLAKATEWTQVE  584
            GEP+P++  E+G + A+PES LP+ LP   D +P         +  ++PLA+ T+W +V 
Sbjct  426  GEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTDWLEVT  477

Query  585  LDLGDGLKKYTRDTNVMPQWAGSSWYQLRYIDPTNSEAFCDIENERYWTGPRSAEDSGGV  644
             +  DG+K   R+TN MPQWAGSSWY LRYIDP N+E + D E  + W           V
Sbjct  478  RE--DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLP---------V  525

Query  645  DLYVGGVEHAVLHLLYSRFWHKVLFDLGFVTSREPYRRLFNQGYIQAFAYTDSRGVYVPA  704
            D+YVGG EHAVLHLLY+RFWHKVL+DLG V ++EP+++LFNQG I + +Y DSRG  V++
Sbjct  526  DIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVAT  585

Query  705  EEVEEKDGKFYY--QGEEVNQEYGKMGKSLKNAVAPDDICRDFGADTLRVYEMAMGPLDT  762
            + VE +DG F+    GEE++Q  +KM+KSLKN V PDD+  ++GADTLRVYEM MGPLD+
Sbjct  586  DKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  763  SRPWSTKDVIGAHRFLQRLWRLVVSEDDGSIVVTDAALTDDDLKQLHRTIAGMRDDYEGL  822
            S +WS  ++ G+++FL+R+ RL+ + +     +T+      D K  + T+ ++ ++ + +
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLITTKE-----ITEENSGALD-KVYNETVKAVTEQVDQM  699

Query  823  RINTVVAKAIEYVNYLTKAYGSTGAPRAAVEPLVIMVAAVAPHIAEELWKRL-GHNDTIT  881
            ++NT +A+ + +VN   K              +V ++A+ APH++EELW+ L +  ++I+
Sbjct  700  KFNTAIAQLMVFVNAANKE---DKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESIS  756

Query  882  FVPFPEYEDKWLVDDEVEMPVQINGKVRARIMVPADASQDQISEIALASDAVTTHIEGKN  941
            +VP P Y++  LV+++VE+ VQI+GKV+A+++V+ D S++++ E+ALA++ V ++I GK+
Sbjct  757  YVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKD  816

Query  942  VIKKIVVPGRMVNLVVK  958
            +IK I VP ++VN+V+K
Sbjct  817  IIKVIAVPNKLVNIVIK  833


 Score =  140 bits (514),  Expect = 5e-34, Method: Compositional matrix adjust.
 Identities = 80/149 (54%), Positives = 104/149 (70%), Gaps = 10/149 (6%)

Query  25   GEIERSWQQYWIDNGTFNAPNPVGDLAVSGDKLPEDKLFVQDMFPYPSGAGLHVGHPLGY  84
              IE  WQ +W DN TF+          +G   +  K++  DMFPYPSGAGLHVGHP GY
Sbjct  7    TAIEPKWQAFWADNHTFK----------TGTDASKPKFYALDMFPYPSGAGLHVGHPEGY  56

Query  85   IATDVFARFNRMLGKNVLHTLGYDAFGLPAEQYAIQTGTHPRTTTMANIANMQRQLGALG  144
             ATD+++RF+R  G NVLH +G DAFGLPAEQYA++TG +P   T  NIAN +RQ+ ALG
Sbjct  57   TATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALG  116

Query  145  LGHDPRRSVATTDPEFYKWTQWIFLQIFN  173
            ++ D  R V TTDP++YKWTQWIF ++++
Sbjct  117  FSYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1425) leuS in NC_016790


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  523 bits (1972),  Expect = 3e-149, Method: Compositional matrix adjust.
 Identities = 349/737 (48%), Positives = 506/737 (69%), Gaps = 57/737 (7%)

Query  228  LVYRSHSMVNWCPGLGTVLANEEVTADGRSERGNFPVFRKKLSQWMMRITAYSdrliddl  287
            L Y ++  VNW   LGT +ANEEV +DG SERG +PV RK + QWM++ITAY++RL++DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  288  dlldwpdKVKSMQRNWIGRSRGAEVDFD--ALGHTITVFTTRPDTLFGASYMVLAPEHEL  345
            + +DWP+ +K MQRNWIG+S GA+V F     +  +TVFTTRPDTLFGA+Y VLAPEH L
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  346  VDALVAAGTNSYEGIDPRWTFGQATPAEAVKAYRASIAAKSDLERQE-NKEKTGVYLGVN  404
            VDA+ +++                  AEAV  Y+   + KSDL R +  KEKTGV  G  
Sbjct  268  VDAITTSD-----------------QAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSY  310

Query  405  AVNPVNGESIPVFIGDYVLTGYGTGAIMAVPAHDTRDYEFATEFGLPIREVVAGGNIAEE  464
            A+NPVNG  +PV I+DYVL++YGTGAIMAVPAHD RD EFA +F L I  V+ GGN+ E 
Sbjct  311  AINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEA  370

Query  465  AYTESGAAVNSANDQGLDINGLDKQEAIAQVIEWLVDKQKGSEKIQYKLRDWLFARQRYW  524
            A+TE G  +NS       ++GLDK  AIA+++EWL     G+E++ Y+LRDWLF+RQRYW
Sbjct  371  AFTEDGLHINSDF-----LDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYW  425

Query  525  GEPFPVVYDENGLAHALPESMLPVELPEVEDYKPVSFDPDDADSEPHPPLAKATEWTQVE  584
            GEP+P++  E+G + A+PES LP+ LP   D +P         +  ++PLA+ T+W +V 
Sbjct  426  GEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTDWLEVT  477

Query  585  LDLGDGLKKYTRDTNVMPQWAGSSWYQLRYIDPTNSEAFCDIENERYWTGPRSAEDSGGV  644
             +  DG+K   R+TN MPQWAGSSWY LRYIDP N+E + D E  + W           V
Sbjct  478  RE--DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLP---------V  525

Query  645  DLYVGGVEHAVLHLLYSRFWHKVLFDLGFVTSREPYRRLFNQGYIQAFAYTDSRGVYVPA  704
            D+YVGG EHAVLHLLY+RFWHKVL+DLG V ++EP+++LFNQG I + +Y DSRG  V++
Sbjct  526  DIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVAT  585

Query  705  EEVEEKDGKFYY--QGEEVNQEYGKMGKSLKNAVAPDDICRDFGADTLRVYEMAMGPLDT  762
            + VE +DG F+    GEE++Q  +KM+KSLKN V PDD+  ++GADTLRVYEM MGPLD+
Sbjct  586  DKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  763  SRPWSTKDVIGAHRFLQRLWRLVVSEDDGSIVVTDAALTDDDLKQLHRTIAGMRDDYEGL  822
            S +WS  ++ G+++FL+R+ RL+ + +     +T+      D K  + T+ ++ ++ + +
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLITTKE-----ITEENSGALD-KVYNETVKAVTEQVDQM  699

Query  823  RINTVVAKAIEYVNYLTKAYGSTGAPRAAVEPLVIMVAAVAPHIAEELWKRL-GHNDTIT  881
            ++NT +A+ + +VN   K              +V ++A+ APH++EELW+ L +  ++I+
Sbjct  700  KFNTAIAQLMVFVNAANKE---DKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESIS  756

Query  882  FVPFPEYEDKWLVDDEVEMPVQINGKVRARIMVPADASQDQISEIALASDAVTTHIEGKN  941
            +VP P Y++  LV+++VE+ VQI+GKV+A+++V+ D S++++ E+ALA++ V ++I GK+
Sbjct  757  YVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKD  816

Query  942  VIKKIVVPGRMVNLVVK  958
            +IK I VP ++VN+V+K
Sbjct  817  IIKVIAVPNKLVNIVIK  833


 Score =  140 bits (514),  Expect = 5e-34, Method: Compositional matrix adjust.
 Identities = 80/149 (54%), Positives = 104/149 (70%), Gaps = 10/149 (6%)

Query  25   GEIERSWQQYWIDNGTFNAPNPVGDLAVSGDKLPEDKLFVQDMFPYPSGAGLHVGHPLGY  84
              IE  WQ +W DN TF+          +G   +  K++  DMFPYPSGAGLHVGHP GY
Sbjct  7    TAIEPKWQAFWADNHTFK----------TGTDASKPKFYALDMFPYPSGAGLHVGHPEGY  56

Query  85   IATDVFARFNRMLGKNVLHTLGYDAFGLPAEQYAIQTGTHPRTTTMANIANMQRQLGALG  144
             ATD+++RF+R  G NVLH +G DAFGLPAEQYA++TG +P   T  NIAN +RQ+ ALG
Sbjct  57   TATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALG  116

Query  145  LGHDPRRSVATTDPEFYKWTQWIFLQIFN  173
            ++ D  R V TTDP++YKWTQWIF ++++
Sbjct  117  FSYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1426) Mspyr1_53210 in NC_014814


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  523 bits (1973),  Expect = 3e-149, Method: Compositional matrix adjust.
 Identities = 349/732 (48%), Positives = 492/732 (68%), Gaps = 51/732 (6%)

Query  222  LVYLADSVVNWCPGLGTVLANEEVTADGRSERGNFPVFRKRLRQWMMRITAYSDRLLEDL  281
            L Y A+  VNW   LGT +ANEEV +DG SERG +PV RK +RQWM++ITAY++RLLEDL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  282  DVLDWPDKVKTMQRNWIGRSTGAEVQFSTAAGDIE--AFTTRPDTLFGATYMVLAPEHDL  339
            + +DWP+ +K MQRNWIG+STGA+V F     D +   FTTRPDTLFGATY VLAPEH L
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  340  VDRLVASAWPDGTDARWTFGAATPAEAVAAYRAGIAAKSDLERQE-NKTKTGVFLGAYAT  398
            VD               ++ ++  AEAVA Y+   + KSDL R +  K KTGV  G+YA 
Sbjct  268  VD---------------AITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAI  312

Query  399  NPANGQQVPVFIADYVLAGYGTGAIMAVPSGDQRDWDFATEFGLPIVEVVAGGDVTVEAY  458
            NP NG+++PV IADYVLA+YGTGAIMAVP+ D+RDW+FA +F L I+ V+ GG+V   A+
Sbjct  313  NPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEAAF  372

Query  459  SGDGMMVNSGFLDGMDVATAKQAMTERLVADGRGRARVEYKLRDWLFARQRYWGEPFPVV  518
            + DG+ +NS+FLDG+D A+A   M E+L A+G G   V Y+LRDWLF+RQRYWGEP+P++
Sbjct  373  TEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPII  432

Query  519  YDSEGRAHGLPEGMLPVELPDVPDYSPVSFDPDDAGSEPSPPLGKVTDWVNVDLDLGDGL  578
               +G + ++PE+ LP+ LP   D  P        ++   +PL++VTDW++V  +  DG+
Sbjct  433  HWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTDWLEVTRE--DGV  482

Query  579  KPYTRDTNVMPQWAGSSWYELRYTDPYNSEALCAKENEAYWMGPRPAEHGPDDPGGVDLY  638
            K   R+TN MPQWAGSSWY LRY DP N+E L   E    W+              VD+Y
Sbjct  483  KG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWL-------------PVDIY  528

Query  639  VGGVEHAVLHLLYSRFWHKVLYDLGHVSSREPYRRLVNQGYIQAFAYTDSRGSYVPAAEV  698
            VGG EHAVLHLLY+RFWHKVLYDLG V+++EP+++L NQG I + +Y DSRG+ V++  V
Sbjct  529  VGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKV  588

Query  699  IERDGKFFWPGPDGETEVNQEFGKIGKSLKNSVSPDEICDNYGADTLRVYEMSMGPLEAS  758
              RDG FF    +   E++Q  +K++KSLKN V+PD++ ++YGADTLRVYEM MGPL+AS
Sbjct  589  EKRDGSFF--HVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  759  RPWATKDVVGAYRFLQRVWRLVVDENTGETLATEDALDEDTLRLLHRTIAGTADDYASLR  818
             +W+  ++ G+ +FL+RV RL+   +  E     +ALD    ++ + T+ + +++   ++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLITTKEITE--ENSGALD----KVYNETVKAVTEQVDQMK  700

Query  819  NNTAAAKLIEYTNHLTKQSVTARAALEPLVLMVAPLAPHLAEELWKRLGHEC-SLAHGPF  877
             NTA A+L+ + N   K+          +V ++AP+APHL+EELW+ L     S++  P 
Sbjct  701  FNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPW  760

Query  878  PVADERYLVEDTVEYPVQVNGKVRGRVTvpadapadaveaaalaeekvvaFLDGRTPKKV  937
            P  DE  LVE+ VE  VQ++GKV++++ V+ D + + ++  ALA+EKV A + G+   KV
Sbjct  761  PSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKV  820

Query  938  IVVAGRLVNVVV  949
            I V+ +LVN+V+
Sbjct  821  IAVPNKLVNIVI  832


 Score =  130 bits (476),  Expect = 5e-31, Method: Compositional matrix adjust.
 Identities = 76/148 (52%), Positives = 98/148 (67%), Gaps = 11/148 (7%)

Query  25   IERAWQQQWADSGTFHVDNPVGSLAPADGSAVPADKMFVQDMFPYPSGEGLHVGHPLGYI  84
            IE  WQ  WAD+ TF             G+  +  K +  DMFPYPSG GLHVGHP GY 
Sbjct  9    IEPKWQAFWADNHTFKT-----------GTDASKPKFYALDMFPYPSGAGLHVGHPEGYT  57

Query  85   ATDVYARYYRMTGRNVLHALGFDAFGLPAEQYAIQTGTHPRTRTEANIVNFRRQLGRLGL  144
            ATD+ +R+ R  G+NVLH++G DAFGLPAEQYA++TG +P   T  NI NF+RQ+  LG+
Sbjct  58   ATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGF  117

Query  145  GHDSRRSFATTDVDYYKWTQWIFLQIFN  172
            + D  R   TTD +YYKWTQWIF ++++
Sbjct  118  SYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1427) leuS in NC_009648


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  522 bits (1971),  Expect = 3e-149, Method: Compositional matrix adjust.
 Identities = 364/865 (43%), Positives = 549/865 (64%), Gaps = 46/865 (5%)

Query  5    YRPEEIESKVQLHWDENRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIA  63
            Y    IE+K Q  W +N+TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKTMQRNWIGRSEGVEISFDVNDYADK  242
            V RK + QW +KITAYA+ LL+DL+ +D WP+++K MQRNWIG+S G +++F V+D    
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGCTY--LavaaghplaqqaaannpalaTFIDECR-NTKVAEADMATME  299
            +TV+TTRPDT+ G TY  LA   +   A  ++ +  A+A +  +   ++ +A +D+A  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGVDTGFKAIHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPV  359
            K GV TG  AI+P+ G E+PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L+I PV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  360  ILAADGSEPDLSEQALTEKGVLFNSGEFSGLDYEAGFNAIADKLAAMGVGERKVNYRLRD  419
            +        ++ E A+TE G+ +NS+ + GLD  +++  + + L A GVG+ +V YRLRD
Sbjct  362  L-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMVTLEDGTVLPTPEDQLPVILP--EDVVMDGIT-SPIKADPEWAKT  476
            W  SRQRYWG PIP++  EDGT  + PE +LP++LP   D+   G   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  T-VNGQPALRETDTFDTFMESSWYYARYTCPQYQEGMLDSKAANYWLPVDIYIGGIEHAI  535
            T  +G  + RET+T      SSWYY RY  P+  E + D    + WLPVDIY+GG EHA+
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVER  595
            +HLLY RF HK++ D G+V + EP ++L+ QGM+L+ ++      + R  + + D +  R
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEKR  591

Query  596  DEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMT  655
            D  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D +
Sbjct  592  D--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  656  LEWQESGVEGANRFLKRVWKLVYEHTTKGEVAALNVAALSEDQKALRRDIHKTIAKVTDD  715
            + W E G+EG+ +FL RV +L+    T  E++        E+  AL +  + T+  VT++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLI----TTKEITE-------ENSGALDKVYNETVKAVTEQ  695

Query  716  IGRRQTFNTAIAAIMELMNKLAKAPQEDEQDRALMQEALLAVVRMLNPFTPHASFTLWRE  775
            +++ + FNTAIA +M ++N         +++  L  +   + V+++ PF+PH +  LW+ 
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  776  LNGEGD-IDNAPWPVADESAMVEDSTLVVVQVNGKVRGKITVAVDATEEQVRERAGQEHL  834
            L + G+ I   PWP  DES +VE+   +VVQ++GKV++K+ VA D + E+++E A  ++ 
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  835  VAKYLDGKTVRKVIYVPGKLLNLVV  859
            V   + GK + KVI VP KL+N+V+
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVI  832

1428) Noc_2665 in NC_007484


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  522 bits (1971),  Expect = 3e-149, Method: Compositional matrix adjust.
 Identities = 359/844 (43%), Positives = 529/844 (63%), Gaps = 77/844 (9%)

Query  21   HQSFRASEDPSKEKFYCLSMFPYPSGR-LHMGHVRNYTIGDVISRYQRMRGRNVLQPMGW  79
            +++F+++ D+SK KFY L MFPYPSG  LH+GH   YT  D++SR++R +G+NVL+PMGW
Sbjct  20   NHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSRFKRAQGHNVLHPMGW  79

Query  80   DAFGLPAENAAIQNRVPPAQWTYENIDHMRRQLKRLGFAYDWSRELATCQPDYYRWEQWL  139
            DAFGLPAE+ A++    PA+ T ENI + +RQ++ LGF+YDW RE+ T +P+YY+W QW+
Sbjct  80   DAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWI  139

Query  140  FTKLFAKGLVYKKTALVNWDPVDQTVLANEQVI-DGRGWRSGALVERREIPQWFLKITAY  198
            FTKL+ KGL Y     VNW     T +ANE+V+ DG + R+G  V R+ + QW LKITAY
Sbjct  140  FTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAY  199

Query  199  GEELLTALDGLTGWPEQVRAMQRNWIGRSEGIEVQFHVEGKE-ALAVFTTRPDTLMGVTF  257
            +E LL  L+ + +WPE ++ MQRNWIG+S G +V F V + +  ++VFTTRPDTL G T+
Sbjct  200  AERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATY  258

Query  258  VSVAAEHPLAREAATSNPALAAFLEQCQRTATSEAILE----TLEKEGMDTGFKAIHPIT  313
              +A+EH+L    +TS+ A A  + + +R A+  + L     + EK G+ TG  AI+P+ 
Sbjct  259  AVLAPEHALVDAITTSDQAEA--VADYKRQASLKSDLARTDLAKEKTGVWTGSYAINPVN  316

Query  314  GEAVPIWVANFVLMGYGTGAVMAVPAHDQRDYEFAKVYGLPIQQVIAPKDDQASCNLEQS  373
            G  +P+W+A++VL +YGTGA+MAVPAHD+RD EFAK + L I  V+       + N+E++
Sbjct  317  GKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL------EGGNVEEA  370

Query  374  AFVEKGLLINSGDFTGLDFDQAFAAIAEHLERGGKGQRRVNYRLRDWGVSRQRYWGAPIP  433
            AF E GL INS+ + GLD   A+A + E LE  G G+  V YRLRDW  SRQRYWG PIP
Sbjct  371  AFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIP  430

Query  434  IVH--CLHCGAIpvpeedlpvvlpervRFDGI-RSPLKQLPEFYQTSCPQCGGQAKRETD  490
            I+H       A+P +E  L + +   +R  G   SPL ++ +  + +  + G +++RET+
Sbjct  431  IIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED-GVKGRRETN  489

Query  491  TFDTFFESSWYYARYCCPDNNATMVDER-GDYWLPVDQYIGGIEHAVLHLLYARFFHKVM  549
            T      SSWYY RY  P+N   + DE     WLPVD Y+GG EHAVLHLLYARF HKV+
Sbjct  490  TMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWHKVL  549

Query  550  RDMGLVRSDEPFTHLLTQGMVL-------------------KDG---------------A  575
             D+G+V + EPF  L+ QGM+L                   +DG               A
Sbjct  550  YDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEELEQAPA  609

Query  576  KMSKSKGNTVDPQALIEHYGADTARLFIMFAAPPEQSLEWSESGVEGAHRFLKRLWRIVA  635
            KMSKS  N V+P+ ++E+YGADT R++ MF +P + S+ WSE G+EG+++FL R+ R+++
Sbjct  610  KMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLIT  669

Query  636  AHVEQDPKAALTLKVKDLNSEQKSFRAKVHETIAKASDDIGRRYTFNTAIAAIMELMNAL  695
            +              K++  E+ +   KV +   KA  +   +  FNTAIA +M      
Sbjct  670  T--------------KEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMV-----  710

Query  696  AKFDDSSPQGQAIRQEALEAVVLLLSPITPHICHRLWQELGHREAIIG-VPWPEADPDAL  754
              F +++ + + +  +   + V L++P++PH+ + LWQ L      I+ VPWP  D   L
Sbjct  711  --FVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKL  768

Query  755  AKESIELVVQVNGKRRGQITVAVQAPREEIEGQAQAEPNVQRFIEGKTVQKVIIVPNRLV  814
              + +E+VVQ++GK ++++ VA + +REE++  A A+ +VQ  I GK + KVI VPN+LV
Sbjct  769  VENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLV  828

Query  815  NLVV  818
            N+V+
Sbjct  829  NIVI  832

1429) leuS in NC_012691


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  522 bits (1971),  Expect = 3e-149, Method: Compositional matrix adjust.
 Identities = 354/864 (41%), Positives = 553/864 (65%), Gaps = 46/864 (5%)

Query  8    YNPQSLEPEVQRHWDKQQTFKAFEKVDKEKFYCLSMFPYPSGR-LHMGHVRNYTIGDVIS  66
            Y+  ++EP  Q  W  ++TFK+     K KFY L MFPYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  67   RYQRLNGKNVLQPIGWDAFGLPAENAAIKNNSAPAKWTYENIEYMKGQLKMLGLSYDWDR  126
            R++R +G NVL+P+GWDAFGLPAE+ A+   + PA  T ENI   K Q++ LG+SYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  127  ELATCTPQYYRWEQWFFTELYKKGLVYKKTSSVNWCPNDQTVLANEQV-QDGCCWRCDTP  185
            E+ T  P+YY+W QW+FT LY KGL Y    +VNW  +  T +ANE+V  DG   R + P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  186  VEQKEIPQWFVKITAYAEELLTDLDKLDGWPEMVKTMQRNWIGRSEGLTMTFHVENSEQS  245
            V +K + QW +KITAYAE LL DL+ +D WPE +K MQRNWIG+S G  +TF V ++++ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  246  FDIYTTRPDTLMGVTYVAVAAAHPlakqaaennaaladfl---eeCKNTKVAEAELATME  302
            F ++TTRPDTL G TY  +A+ H+L    + ++ A A      +   ++ +A ++LA  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  303  KKGMATGLYALHPLDGRRVPIMVANFVLMDYGTGAVMAVPAHDQRDFEFAHKYGLEIRAV  362
            K G+ TG YA++P++G+ +P+ +A++VL  YGTGA+MAVPAHD+RD EFA ++ L+I +V
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  363  IAAEDGSAPDISAAAYTEKGVLFNSGEFDGLDFKQAFDAICTKLESQGLGKRTVNFRLRD  422
            + +      ++  AA+TE G+ +NS+ +DGLD   A+  +   LE++G+G+  V +RLRD
Sbjct  362  LEGG-----NVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  423  WGVSRQRYWGAPIPMLTLEDGTVVPAPADQLPVILP--EDVVMDGV-QSPIKADPEWAKT  479
            W  SRQRYWG PIP++  EDGT  + P  +LP++LP   D+   G  +SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  480  TY-NGQPALRETDTFDTFMESSWYFARYCCPDYEQGMLDTDRANHWLPVDQYIGGIEHAC  538
            T  +G  + RET+T      SSWY+ RY  P+  + + D +  ++WLPVD Y+GG EHA 
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  539  MHLLYARFFHKLLRDSGMVKSDEPFTRLLCQGMVLADAFYYTEHGARVWVSPTDVKVERD  598
            +HLLYARF HK+L D G+V + EPF +L+ QGM+L+ + Y   +GA V    +  KVE+ 
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS-YRDSRGALV----ATDKVEKR  591

Query  599  EKGRIIKAVDNEGREVIHAGMTKMSKSKNNGIDPQLMVERYGADTVRLFMMFASPADMTL  658
            + G ++     E  E ++ + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D ++
Sbjct  592  D-GSFFHV---ETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASI  647

Query  659  EWQESGVDGAQRFLKRLWKAVAEHTAKGAAPELDVASLSNEQKTLRRELHKTIAKFSDDI  718
             W E G++G+++FL R+ + ++        +            +L +  + T+   ++++
Sbjct  648  AWSEEGLEGSRKFLDRVYRLITTKEITEENSG-----------ALDKVYNETVKAVTEQV  696

Query  719  GRRQTFNTAIAAVMELMNRVAKAPQESDQDRALVQEVLTNVVLMLYPITPHVCFHLWQAL  778
            ++ + FNTAIA +M ++N        ++++  L  +     V ++ P++PH+  +LWQAL
Sbjct  697  DQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQAL  748

Query  779  GNAD--IDQaawpvadaaaMVEDEKLVVVQVNGKVRGKLTVAADATQEQVQALAMQDHTV  836
              ++  I   +WP  D + +VE++  +VVQ++GKV++KL VA D ++E++Q +A+ ++ V
Sbjct  749  TASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKV  808

Query  837  AKFTADLTVRKVIYVPGKLLNIVV  860
                A+  + KVI VP KL+NIV+
Sbjct  809  QAEIAGKDIIKVIAVPNKLVNIVI  832

1430) leuS in NC_008595


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  522 bits (1970),  Expect = 4e-149, Method: Compositional matrix adjust.
 Identities = 359/741 (49%), Positives = 506/741 (69%), Gaps = 59/741 (7%)

Query  255  LVYRADSMVNWCPGLGTVLANEEVTADGRSDRGNFPVFRKRLRQWMMRITAYSdrllddl  314
            L Y A+  VNW   LGT +ANEEV +DG S+RG +PV RK +RQWM++ITAY++RLL+DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  315  dlldWPEPVKTMQRNWIGRStgakalfaatgadgaaldIEVFTTRPDTLFGATYMVLAPE  374
            + +DWPE++K MQRNWIG+STGA+  F   ++D     + VFTTRPDTLFGATY VLAPE
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKD---FTVFTTRPDTLFGATYAVLAPE  264

Query  375  HELVDELVAPAWPDGTDPRWTYGAATPGEAVAAYRRAIASKSDLERQE-SKAKTGVFLGS  433
            H LVD + ++                 +EAVA Y+R  + KSDL R + +K KTGV  GS
Sbjct  265  HALVDAITTSD---------------QAEAVADYKRQASLKSDLARTDLAKEKTGVWTGS  309

Query  434  YATNPTNGKPVPIFIADYVLAGYGTGAIMAVPGHDQRDWDFAHEFGLPIVEVIAGGDISE  493
            YA NP NGK +P+ IADYVLA+YGTGAIMAVP+HD+RDW+FA +F L I+ V+ GG++ E
Sbjct  310  YAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEE  369

Query  494  GAYAGDGLLVNSGYLDGLDVAAAKEAITARLEAEGRGCARVEFKLRDWLFARQRYWGEPF  553
            +A++ DGL +NS++LDGLD A+A   +  +LEAEG G   V ++LRDWLF+RQRYWGEP+
Sbjct  370  AAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPI  429

Query  554  PIVYDSDGRPHALDEAALPVELPDVPDYSPVLFdpddadsepsppLAKATDWVHVELDLG  613
            PI+   DG + A+ E+ LP+ LP   D  P         +   +PLA+ TDW++V  +  
Sbjct  430  PIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTDWLEVTRE--  479

Query  614  DGLKPYSRDTNVMPQWAGSSWYELRYTDPHNSERFCAKENEAYWMGPRPAEHGPQDPGGV  673
            DG+K   R+TN MPQWAGSSWY LRY DPHN+E++   E    W+              V
Sbjct  480  DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWL-------------PV  525

Query  674  DLYVGGAEHAVLHLLYARFWHKVLYDLGHVSSREPYRRLVNQGYIQAFAYTDSRGSYVPA  733
            D+YVGGAEHAVLHLLYARFWHKVLYDLG V+++EP+++L NQG I + +Y DSRG+ V++
Sbjct  526  DIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVAT  585

Query  734  EEVVERDGRFFYRGPDGEIEVFQEFGKIGKSLKNSISPDEICDDYGADTLRVYEMSMGPL  793
            + V  RDG FF    + E+E  Q  +K++KSLKN ++PD++ ++YGADTLRVYEM MGPL
Sbjct  586  DKVEKRDGSFFHVETGEELE--QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPL  643

Query  794  EASRPWATKDVVGAHRFLQRVWRLVVDEQTGETRVVDGAGRDLPTGTL-RLLHRTIAGVS  852
            +AS +W+  ++ G+++FL+RV RL+   +  E            +G+L ++ + T+ +V+
Sbjct  644  DASIAWSEEGLEGSRKFLDRVYRLITTKEITEEN----------SGALDKVYNETVKAVT  693

Query  853  EDYAGLRNNTAVAKLIEYTNHLTKEHRDAVPRAAVEPLVLMLAPLAPHMAEELWLRLGHT  912
            E+   ++ NTA+A+L+ + N   KE++  +       +V ++AP+APH++EELW  L  +
Sbjct  694  EQVDQMKFNTAIAQLMVFVNAANKEDK--LFSDYAKGFVQLIAPFAPHLGEELWQALTAS  751

Query  913  T-SLAHGPFPVADPAYLVEDTVEYPVQVNGKVRGRVTVAADADRDTLEAAALADEKVLAF  971
              S++  P P  D + LVE+ VE  VQ++GKV++++ VA D  R+ L+  ALA+EKV A 
Sbjct  752  GESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAE  811

Query  972  LAGAQPRKVIVVPGRLVNLVV  992
            +AG +  KVI VP +LVN+V+
Sbjct  812  IAGKDIIKVIAVPNKLVNIVI  832


 Score =  128 bits (470),  Expect = 2e-30, Method: Compositional matrix adjust.
 Identities = 75/148 (51%), Positives = 99/148 (67%), Gaps = 11/148 (7%)

Query  58   IEGSWQDTWAKLGTFNVPNPVGSLAPTDGTPVPEDKLFVQDMFPYPSGEGLHVGHPLGYI  117
            IE  WQ  WA   TF+            GT  +  K++  DMFPYPSG GLHVGHP GY 
Sbjct  9    IEPKWQAFWADNHTFKT-----------GTDASKPKFYALDMFPYPSGAGLHVGHPEGYT  57

Query  118  ATDVYARYFRMTGRNVLHALGFDAFGLPAEQYAVQTGTHPRTRTEANVVNFRRQLGRLGL  177
            ATD+ +R+ R  G+NVLH++G DAFGLPAEQYA++TG +P   T  N+ NF+RQ+  LG+
Sbjct  58   ATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGF  117

Query  178  GHDSRRSFSTTDVEFYKWTQWIFLQIYN  205
            + D  R  +TTD ++YKWTQWIF ++Y+
Sbjct  118  SYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1431) leuS in NC_002944


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  522 bits (1970),  Expect = 4e-149, Method: Compositional matrix adjust.
 Identities = 358/741 (49%), Positives = 506/741 (69%), Gaps = 59/741 (7%)

Query  232  LVYRADSMVNWCPGLGTVLANEEVTADGRSDRGNFPVFRKRLRQWMMRITAYSdrllddl  291
            L Y A+  VNW   LGT +ANEEV +DG S+RG +PV RK +RQWM++ITAY++RLL+DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  292  dlldWPEPVKTMQRNWIGRStgakalfaatgadgaaldIEVFTTRPDTLFGATYMVLAPE  351
            + +DWPE++K MQRNWIG+STGA+  F   ++D     + VFTTRPDTLFGATY VLAPE
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKD---FTVFTTRPDTLFGATYAVLAPE  264

Query  352  HELVDELVAPAWPDGTDPRWTYGAATPGESVAAYRRAIASKSDLERQE-SKAKTGVFLGS  410
            H LVD + ++                 +E+VA Y+R  + KSDL R + +K KTGV  GS
Sbjct  265  HALVDAITTSD---------------QAEAVADYKRQASLKSDLARTDLAKEKTGVWTGS  309

Query  411  YATNPTNGKPVPIFIADYVLAGYGTGAIMAVPGHDQRDWDFAHEFGLPIVEVIAGGDISE  470
            YA NP NGK +P+ IADYVLA+YGTGAIMAVP+HD+RDW+FA +F L I+ V+ GG++ E
Sbjct  310  YAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEE  369

Query  471  GAYAGDGVLVNSGYLDGLDVAAAKEAITARLEAEGRGCARVEYKLRDWLFARQRYWGEPF  530
            +A++ DG+ +NS++LDGLD A+A   +  +LEAEG G   V Y+LRDWLF+RQRYWGEP+
Sbjct  370  AAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPI  429

Query  531  PIVYDSDGRPHALDEAALPVELPDVPDYSPVLFdpddadsepsppLAKATDWVHVELDLG  590
            PI+   DG + A+ E+ LP+ LP   D  P         +   +PLA+ TDW++V  +  
Sbjct  430  PIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTDWLEVTRE--  479

Query  591  DGLKPYSRDTNVMPQWAGSSWYELRYTDPHNSERFCAKENEAYWMGPRPAEHGPQDPGGV  650
            DG+K   R+TN MPQWAGSSWY LRY DPHN+E++   E    W+              V
Sbjct  480  DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWL-------------PV  525

Query  651  DLYVGGAEHAVLHLLYARFWHKVLYDLGHVSSREPYRRLVNQGYIQAFAYTDSRGSYVPA  710
            D+YVGGAEHAVLHLLYARFWHKVLYDLG V+++EP+++L NQG I + +Y DSRG+ V++
Sbjct  526  DIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVAT  585

Query  711  EEVVERDGRFFYRGPDGEIEVFQEFGKIGKSLKNSISPDEICDDYGADTLRVYEMSMGPL  770
            + V  RDG FF    + E+E  Q  +K++KSLKN ++PD++ ++YGADTLRVYEM MGPL
Sbjct  586  DKVEKRDGSFFHVETGEELE--QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPL  643

Query  771  EASRPWATKDVVGAHRFLQRVWRLVVDEQTGETRVVDGAGRDLPTGTL-RLLHRTIAGVS  829
            +AS +W+  ++ G+++FL+RV RL+   +  E            +G+L ++ + T+ +V+
Sbjct  644  DASIAWSEEGLEGSRKFLDRVYRLITTKEITEEN----------SGALDKVYNETVKAVT  693

Query  830  EDYAALRNNTAVAKLIEYTNHLTKEHRDAVPRAAVEPLVLMLAPLAPHMAEELWLRLGHT  889
            E+   ++ NTA+A+L+ + N   KE++  +       +V ++AP+APH++EELW  L  +
Sbjct  694  EQVDQMKFNTAIAQLMVFVNAANKEDK--LFSDYAKGFVQLIAPFAPHLGEELWQALTAS  751

Query  890  T-SLAHGPFPVADPAYLVEDTVEYPVQVNGKVRGRVTVAADADRDTLEAAALADEKVLAF  948
              S++  P P  D + LVE+ VE  VQ++GKV++++ VA D  R+ L+  ALA+EKV A 
Sbjct  752  GESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAE  811

Query  949  LAGAQPRKVIVVPGRLVNLVV  969
            +AG +  KVI VP +LVN+V+
Sbjct  812  IAGKDIIKVIAVPNKLVNIVI  832


 Score =  129 bits (471),  Expect = 1e-30, Method: Compositional matrix adjust.
 Identities = 75/148 (51%), Positives = 99/148 (67%), Gaps = 11/148 (7%)

Query  35   IEGSWQDTWAKLGTFNVPNPVGSLAPTDGTPVPEDKLFVQDMFPYPSGEGLHVGHPLGYI  94
            IE  WQ  WA   TF+            GT  +  K++  DMFPYPSG GLHVGHP GY 
Sbjct  9    IEPKWQAFWADNHTFKT-----------GTDASKPKFYALDMFPYPSGAGLHVGHPEGYT  57

Query  95   ATDVYARYFRMTGRNVLHALGFDAFGLPAEQYAVQTGTHPRTRTEANVVNFRRQLGRLGL  154
            ATD+ +R+ R  G+NVLH++G DAFGLPAEQYA++TG +P   T  N+ NF+RQ+  LG+
Sbjct  58   ATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGF  117

Query  155  GHDSRRSFSTTDVEFYKWTQWIFLQIYN  182
            + D  R  +TTD ++YKWTQWIF ++Y+
Sbjct  118  SYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1432) MAP4_3827 in NC_021200


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  522 bits (1970),  Expect = 4e-149, Method: Compositional matrix adjust.
 Identities = 358/741 (49%), Positives = 506/741 (69%), Gaps = 59/741 (7%)

Query  232  LVYRADSMVNWCPGLGTVLANEEVTADGRSDRGNFPVFRKRLRQWMMRITAYSdrllddl  291
            L Y A+  VNW   LGT +ANEEV +DG S+RG +PV RK +RQWM++ITAY++RLL+DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  292  dlldWPEPVKTMQRNWIGRStgakalfaatgadgaaldIEVFTTRPDTLFGATYMVLAPE  351
            + +DWPE++K MQRNWIG+STGA+  F   ++D     + VFTTRPDTLFGATY VLAPE
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKD---FTVFTTRPDTLFGATYAVLAPE  264

Query  352  HELVDELVAPAWPDGTDPRWTYGAATPGESVAAYRRAIASKSDLERQE-SKAKTGVFLGS  410
            H LVD + ++                 +E+VA Y+R  + KSDL R + +K KTGV  GS
Sbjct  265  HALVDAITTSD---------------QAEAVADYKRQASLKSDLARTDLAKEKTGVWTGS  309

Query  411  YATNPTNGKPVPIFIADYVLAGYGTGAIMAVPGHDQRDWDFAHEFGLPIVEVIAGGDISE  470
            YA NP NGK +P+ IADYVLA+YGTGAIMAVP+HD+RDW+FA +F L I+ V+ GG++ E
Sbjct  310  YAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEE  369

Query  471  GAYAGDGVLVNSGYLDGLDVAAAKEAITARLEAEGRGCARVEYKLRDWLFARQRYWGEPF  530
            +A++ DG+ +NS++LDGLD A+A   +  +LEAEG G   V Y+LRDWLF+RQRYWGEP+
Sbjct  370  AAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPI  429

Query  531  PIVYDSDGRPHALDEAALPVELPDVPDYSPVLFdpddadsepsppLAKATDWVHVELDLG  590
            PI+   DG + A+ E+ LP+ LP   D  P         +   +PLA+ TDW++V  +  
Sbjct  430  PIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTDWLEVTRE--  479

Query  591  DGLKPYSRDTNVMPQWAGSSWYELRYTDPHNSERFCAKENEAYWMGPRPAEHGPQDPGGV  650
            DG+K   R+TN MPQWAGSSWY LRY DPHN+E++   E    W+              V
Sbjct  480  DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWL-------------PV  525

Query  651  DLYVGGAEHAVLHLLYARFWHKVLYDLGHVSSREPYRRLVNQGYIQAFAYTDSRGSYVPA  710
            D+YVGGAEHAVLHLLYARFWHKVLYDLG V+++EP+++L NQG I + +Y DSRG+ V++
Sbjct  526  DIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVAT  585

Query  711  EEVVERDGRFFYRGPDGEIEVFQEFGKIGKSLKNSISPDEICDDYGADTLRVYEMSMGPL  770
            + V  RDG FF    + E+E  Q  +K++KSLKN ++PD++ ++YGADTLRVYEM MGPL
Sbjct  586  DKVEKRDGSFFHVETGEELE--QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPL  643

Query  771  EASRPWATKDVVGAHRFLQRVWRLVVDEQTGETRVVDGAGRDLPTGTL-RLLHRTIAGVS  829
            +AS +W+  ++ G+++FL+RV RL+   +  E            +G+L ++ + T+ +V+
Sbjct  644  DASIAWSEEGLEGSRKFLDRVYRLITTKEITEEN----------SGALDKVYNETVKAVT  693

Query  830  EDYAALRNNTAVAKLIEYTNHLTKEHRDAVPRAAVEPLVLMLAPLAPHMAEELWLRLGHT  889
            E+   ++ NTA+A+L+ + N   KE++  +       +V ++AP+APH++EELW  L  +
Sbjct  694  EQVDQMKFNTAIAQLMVFVNAANKEDK--LFSDYAKGFVQLIAPFAPHLGEELWQALTAS  751

Query  890  T-SLAHGPFPVADPAYLVEDTVEYPVQVNGKVRGRVTVAADADRDTLEAAALADEKVLAF  948
              S++  P P  D + LVE+ VE  VQ++GKV++++ VA D  R+ L+  ALA+EKV A 
Sbjct  752  GESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAE  811

Query  949  LAGAQPRKVIVVPGRLVNLVV  969
            +AG +  KVI VP +LVN+V+
Sbjct  812  IAGKDIIKVIAVPNKLVNIVI  832


 Score =  129 bits (471),  Expect = 1e-30, Method: Compositional matrix adjust.
 Identities = 75/148 (51%), Positives = 99/148 (67%), Gaps = 11/148 (7%)

Query  35   IEGSWQDTWAKLGTFNVPNPVGSLAPTDGTPVPEDKLFVQDMFPYPSGEGLHVGHPLGYI  94
            IE  WQ  WA   TF+            GT  +  K++  DMFPYPSG GLHVGHP GY 
Sbjct  9    IEPKWQAFWADNHTFKT-----------GTDASKPKFYALDMFPYPSGAGLHVGHPEGYT  57

Query  95   ATDVYARYFRMTGRNVLHALGFDAFGLPAEQYAVQTGTHPRTRTEANVVNFRRQLGRLGL  154
            ATD+ +R+ R  G+NVLH++G DAFGLPAEQYA++TG +P   T  N+ NF+RQ+  LG+
Sbjct  58   ATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGF  117

Query  155  GHDSRRSFSTTDVEFYKWTQWIFLQIYN  182
            + D  R  +TTD ++YKWTQWIF ++Y+
Sbjct  118  SYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1433) leuS in NC_002935


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  522 bits (1970),  Expect = 4e-149, Method: Compositional matrix adjust.
 Identities = 350/737 (48%), Positives = 508/737 (69%), Gaps = 57/737 (7%)

Query  230  LVYRSHSMVNWCPGLGTVLANEEVTADGRSERGNFPVFRKKLSQWMMRITAYSdrliddl  289
            L Y ++  VNW   LGT +ANEEV +DG SERG +PV RK + QWM++ITAY++RL++DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  290  dlldwpdKVKSMQRNWIGRSRGAEVDFD--ALGHTITVFTTRPDTLFGASYMVLAPEHEL  347
            + +DWP+ +K MQRNWIG+S GA+V F     +  +TVFTTRPDTLFGA+Y VLAPEH L
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  348  VDALVAAGTNSYEGIDPRWTFGQATPAEAVKAYRASIAAKSDLERQE-NKEKTGVYLGVN  406
            VDA+ +++                  AEAV  Y+   + KSDL R +  KEKTGV  G  
Sbjct  268  VDAITTSD-----------------QAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSY  310

Query  407  AVNPVNGESIPVFIGDYVLTGYGTGAIMAVPAHDTRDYEFATEFGLPIREVVAGGNIAEA  466
            A+NPVNG  +PV I+DYVL++YGTGAIMAVPAHD RD EFA +F L I  V+ GGN+ EA
Sbjct  311  AINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEA  370

Query  467  AYTESGAAVNSANDQGLDINGLDKQEAIAQVIEWLVDKQKGSEKIQYKLRDWLFARQRYW  526
            A+TE G  +NS       ++GLDK  AIA+++EWL     G+E++ Y+LRDWLF+RQRYW
Sbjct  371  AFTEDGLHINSDF-----LDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYW  425

Query  527  GEPFPVVYDENGLAHALPESMLPVELPEVEDYKPVSFDPDDADSEPHPPLAKATEWTQVE  586
            GEP+P++  E+G + A+PES LP+ LP   D +P         +  ++PLA+ T+W +V 
Sbjct  426  GEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTDWLEVT  477

Query  587  LDLGDGLKKYTRDTNVMPQWAGSSWYQLRYIDPTNSEAFCDIENERYWTGPRSAEDSGGV  646
             +  DG+K   R+TN MPQWAGSSWY LRYIDP N+E + D E  + W           V
Sbjct  478  RE--DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLP---------V  525

Query  647  DLYVGGVEHAVLHLLYSRFWHKVLFDLGFVTSREPYRRLFNQGYIQAFAYTDSRGVYVPA  706
            D+YVGG EHAVLHLLY+RFWHKVL+DLG V ++EP+++LFNQG I + +Y DSRG  V++
Sbjct  526  DIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVAT  585

Query  707  EEVEEKDGKFYY--QGEEVNQEYGKMGKSLKNAVAPDDICRDFGADTLRVYEMAMGPLDT  764
            + VE +DG F+    GEE++Q  +KM+KSLKN V PDD+  ++GADTLRVYEM MGPLD+
Sbjct  586  DKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  765  SRPWSTKDVIGAHRFLQRLWRLVVSEDDGSIVVTDAALTDDDLKQLHRTIAGMRDDYEGL  824
            S +WS  ++ G+++FL+R+ RL+ + +   I   +++  D   K  + T+ ++ ++ + +
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLITTKE---ITEENSGALD---KVYNETVKAVTEQVDQM  699

Query  825  RINTVVAKAIEYVNYLTKAYGSTGAPRAAVEPLVIMVAAVAPHIAEELWKRL-GHNDTIT  883
            ++NT +A+ + +VN   K              +V ++A+ APH++EELW+ L +  ++I+
Sbjct  700  KFNTAIAQLMVFVNAANKE---DKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESIS  756

Query  884  FVPFPEYEDKWLVDDEVEMPVQINGKVRARIMVPADASQDQISEIALASEAVATHIEGKN  943
            +VP P Y++  LV+++VE+ VQI+GKV+A+++V+ D S++++ E+ALA+E V ++I GK+
Sbjct  757  YVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKD  816

Query  944  VIKKIVVSGRMVNLVVK  960
            +IK I V+ ++VN+V+K
Sbjct  817  IIKVIAVPNKLVNIVIK  833


 Score =  140 bits (514),  Expect = 5e-34, Method: Compositional matrix adjust.
 Identities = 80/147 (55%), Positives = 104/147 (71%), Gaps = 10/147 (6%)

Query  29   IERSWQQYWIDNGTFNAPNPVGDLAVSGDKLPEDKLFVQDMFPYPSGAGLHVGHPLGYIA  88
            IE  WQ +W DN TF+          +G   +  K++  DMFPYPSGAGLHVGHP GY A
Sbjct  9    IEPKWQAFWADNHTFK----------TGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTA  58

Query  89   TDVFARFNRMLGKNVLHTLGYDAFGLPAEQYAIQTGTHPRTTTMANIANMQRQLGALGLG  148
            TD+++RF+R  G NVLH +G DAFGLPAEQYA++TG +P   T  NIAN +RQ+ ALG++
Sbjct  59   TDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFS  118

Query  149  HDPRRSVATTDPEFYKWTQWIFLQIFN  175
             D  R V TTDP++YKWTQWIF ++++
Sbjct  119  YDWDREVNTTDPNYYKWTQWIFTKLYE  145

1434) A79E_3565 in NC_018522


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  522 bits (1969),  Expect = 4e-149, Method: Compositional matrix adjust.
 Identities = 359/865 (42%), Positives = 551/865 (64%), Gaps = 46/865 (5%)

Query  13   YRPEEIESKVQLHWDENRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIA  71
            Y    IE+K Q  W +N+TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  72   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSR  131
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  132  ELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  190
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  191  VERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKTMQRNWIGRSEGVEISFDVNDYADK  250
            V RK + QW +KITAYA+ LL+DL+ +D WP+++K MQRNWIG+S G +++F V+D    
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  251  LTVYTTRPDTFMGCTY--LavaaghplaqqaaannpalaaFIDECR-NTKVAEADMATME  307
            +TV+TTRPDT+ G TY  LA   +   A  ++ +  A+A +  +   ++ +A +D+A  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  308  KKGVDTGFKAIHPLTGEQIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPV  367
            K GV TG  AI+P+ G ++PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L+I PV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  368  ILAADGSEPDLSEQALTEKGVLFNSGEFSGLDYEAGFNAIADKLTAMGVGERKVNYRLRD  427
            + +++  E+ ++E++L  ++ +++     GLD  +++  + + L A GVG+ +V YRLRD
Sbjct  362  LEGGNVEEAAFTEDGLHINSDFLD-----GLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  428  WGVSRQRYWGAPIPMVTLEDGTVLPTPEDQLPVILP--EDVVMDGIT-SPIKADPEWAKT  484
            W  SRQRYWG PIP++  EDGT  + PE +LP++LP   D+   G   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  485  T-VNGQPALRETDTFDTFMESSWYYARYTCPQYQEGMLDSKAANYWLPVDIYIGGIEHAI  543
            T  +G  + RET+T      SSWYY RY  P+  E + D    + WLPVDIY+GG EHA+
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  544  MHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVER  603
            +HLLY RF HK++ D G+V + EP ++L+ QGM+L+ ++      + R  + + D +  R
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEKR  591

Query  604  DEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMT  663
            D  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D +
Sbjct  592  D--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  664  LEWQESGVEGANRFLKRVWKLVYEHTTKGEVAALNVAALSEDQKALRRDIHKTIAKVTDD  723
            + W E G+EG+ +FL RV +L+    T  E++        E+  AL +  + T+  VT++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLI----TTKEITE-------ENSGALDKVYNETVKAVTEQ  695

Query  724  IGRRQTFNTAIAAIMELMNKLAKAPQEDEQDRALMQEALLAVVRMLNPFTPHASFTLWRE  783
            +++ + FNTAIA +M ++N         +++  L  +   + V+++ PF+PH +  LW+ 
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  784  LNGEGD-IDNAPWPVADESAMVEDSTLVVVQVNGKVRGKITVAVDATEEQVRERAGQEHL  842
            L + G+ I   PWP  DES +VE+   +VVQ++GKV++K+ VA D + E+++E A  ++ 
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  843  VAKYLDGKTVRKVIYVPGKLLNLVV  867
            V   + GK + KVI VP KL+N+V+
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVI  832

1435) KPHS_15130 in NC_016845


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  522 bits (1969),  Expect = 4e-149, Method: Compositional matrix adjust.
 Identities = 363/865 (42%), Positives = 549/865 (64%), Gaps = 46/865 (5%)

Query  5    YRPEEIESKVQLHWDENRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIA  63
            Y    IE+K Q  W +N+TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKTMQRNWIGRSVGVEISFDVNDYADK  242
            V RK + QW +KITAYA+ LL+DL+ +D WP+++K MQRNWIG+S G +++F V+D    
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGCTY--LavaaghplaqqaaannpalaaFIDECR-NTKVAEADMATME  299
            +TV+TTRPDT+ G TY  LA   +   A  ++ +  A+A +  +   ++ +A +D+A  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGVDTGFKAIHPLTGEQIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPV  359
            K GV TG  AI+P+ G ++PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L+I PV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  360  ILAADGSEPDLSEQALTEKGVLFNSGEFSGLDYEAGFNAIADKLAAMGVGERKVNYRLRD  419
            +        ++ E A+TE G+ +NS+ + GLD  +++  + + L A GVG+ +V YRLRD
Sbjct  362  L-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMVTLEDGTVLPTPEDQLPVILP--EDVVMDGIT-SPIKADPEWAKT  476
            W  SRQRYWG PIP++  EDGT  + PE +LP++LP   D+   G   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  T-VNGQPALRETDTFDTFMESSWYYARYTCPQYQEGMLDSKAANYWLPVDIYIGGIEHAI  535
            T  +G  + RET+T      SSWYY RY  P+  E + D    + WLPVDIY+GG EHA+
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVER  595
            +HLLY RF HK++ D G+V + EP ++L+ QGM+L+ ++      + R  + + D +  R
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEKR  591

Query  596  DEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMT  655
            D  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D +
Sbjct  592  D--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  656  LEWQESGVEGANRFLKRVWKLVYEHTTKGEVAALNVAALSEDQKALRRDIHKTIAKVTDD  715
            + W E G+EG+ +FL RV +L+    T  E++        E+  AL +  + T+  VT++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLI----TTKEITE-------ENSGALDKVYNETVKAVTEQ  695

Query  716  IGRRQTFNTAIAAIMELMNKLAKAPQEDEQDRALMQEALLAVVRMLNPFTPHASFTLWRE  775
            +++ + FNTAIA +M ++N         +++  L  +   + V+++ PF+PH +  LW+ 
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  776  LNGEGD-IDNAPWPVADESAMVEDSTLVVVQVNGKVRGKITVAVDATEEQVRERAGQEHL  834
            L + G+ I   PWP  DES +VE+   +VVQ++GKV++K+ VA D + E+++E A  ++ 
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  835  VAKYLDGKTVRKVIYVPGKLLNLVV  859
            V   + GK + KVI VP KL+N+V+
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVI  832

1436) N559_3648 in NC_022082


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  522 bits (1969),  Expect = 4e-149, Method: Compositional matrix adjust.
 Identities = 363/865 (42%), Positives = 549/865 (64%), Gaps = 46/865 (5%)

Query  5    YRPEEIESKVQLHWDENRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIA  63
            Y    IE+K Q  W +N+TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKTMQRNWIGRSVGVEISFDVNDYADK  242
            V RK + QW +KITAYA+ LL+DL+ +D WP+++K MQRNWIG+S G +++F V+D    
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGCTY--LavaaghplaqqaaannpalaaFIDECR-NTKVAEADMATME  299
            +TV+TTRPDT+ G TY  LA   +   A  ++ +  A+A +  +   ++ +A +D+A  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGVDTGFKAIHPLTGEQIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPV  359
            K GV TG  AI+P+ G ++PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L+I PV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  360  ILAADGSEPDLSEQALTEKGVLFNSGEFSGLDYEAGFNAIADKLAAMGVGERKVNYRLRD  419
            +        ++ E A+TE G+ +NS+ + GLD  +++  + + L A GVG+ +V YRLRD
Sbjct  362  L-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMVTLEDGTVLPTPEDQLPVILP--EDVVMDGIT-SPIKADPEWAKT  476
            W  SRQRYWG PIP++  EDGT  + PE +LP++LP   D+   G   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  T-VNGQPALRETDTFDTFMESSWYYARYTCPQYQEGMLDSKAANYWLPVDIYIGGIEHAI  535
            T  +G  + RET+T      SSWYY RY  P+  E + D    + WLPVDIY+GG EHA+
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVER  595
            +HLLY RF HK++ D G+V + EP ++L+ QGM+L+ ++      + R  + + D +  R
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEKR  591

Query  596  DEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMT  655
            D  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D +
Sbjct  592  D--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  656  LEWQESGVEGANRFLKRVWKLVYEHTTKGEVAALNVAALSEDQKALRRDIHKTIAKVTDD  715
            + W E G+EG+ +FL RV +L+    T  E++        E+  AL +  + T+  VT++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLI----TTKEITE-------ENSGALDKVYNETVKAVTEQ  695

Query  716  IGRRQTFNTAIAAIMELMNKLAKAPQEDEQDRALMQEALLAVVRMLNPFTPHASFTLWRE  775
            +++ + FNTAIA +M ++N         +++  L  +   + V+++ PF+PH +  LW+ 
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  776  LNGEGD-IDNAPWPVADESAMVEDSTLVVVQVNGKVRGKITVAVDATEEQVRERAGQEHL  834
            L + G+ I   PWP  DES +VE+   +VVQ++GKV++K+ VA D + E+++E A  ++ 
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  835  VAKYLDGKTVRKVIYVPGKLLNLVV  859
            V   + GK + KVI VP KL+N+V+
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVI  832

1437) leuS in NC_012731


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  522 bits (1969),  Expect = 4e-149, Method: Compositional matrix adjust.
 Identities = 359/865 (42%), Positives = 551/865 (64%), Gaps = 46/865 (5%)

Query  13   YRPEEIESKVQLHWDENRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIA  71
            Y    IE+K Q  W +N+TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  72   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSR  131
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  132  ELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  190
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  191  VERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKTMQRNWIGRSEGVEISFDVNDYADK  250
            V RK + QW +KITAYA+ LL+DL+ +D WP+++K MQRNWIG+S G +++F V+D    
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  251  LTVYTTRPDTFMGCTY--LavaaghplaqqaaannpalaaFIDECR-NTKVAEADMATME  307
            +TV+TTRPDT+ G TY  LA   +   A  ++ +  A+A +  +   ++ +A +D+A  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  308  KKGVDTGFKAIHPLTGEQIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPV  367
            K GV TG  AI+P+ G ++PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L+I PV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  368  ILAADGSEPDLSEQALTEKGVLFNSGEFSGLDYEAGFNAIADKLTAMGVGERKVNYRLRD  427
            + +++  E+ ++E++L  ++ +++     GLD  +++  + + L A GVG+ +V YRLRD
Sbjct  362  LEGGNVEEAAFTEDGLHINSDFLD-----GLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  428  WGVSRQRYWGAPIPMVTLEDGTVLPTPEDQLPVILP--EDVVMDGIT-SPIKADPEWAKT  484
            W  SRQRYWG PIP++  EDGT  + PE +LP++LP   D+   G   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  485  T-VNGQPALRETDTFDTFMESSWYYARYTCPQYQEGMLDSKAANYWLPVDIYIGGIEHAI  543
            T  +G  + RET+T      SSWYY RY  P+  E + D    + WLPVDIY+GG EHA+
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  544  MHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVER  603
            +HLLY RF HK++ D G+V + EP ++L+ QGM+L+ ++      + R  + + D +  R
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEKR  591

Query  604  DEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMT  663
            D  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D +
Sbjct  592  D--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  664  LEWQESGVEGANRFLKRVWKLVYEHTTKGEVAALNVAALSEDQKALRRDIHKTIAKVTDD  723
            + W E G+EG+ +FL RV +L+    T  E++        E+  AL +  + T+  VT++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLI----TTKEITE-------ENSGALDKVYNETVKAVTEQ  695

Query  724  IGRRQTFNTAIAAIMELMNKLAKAPQEDEQDRALMQEALLAVVRMLNPFTPHASFTLWRE  783
            +++ + FNTAIA +M ++N         +++  L  +   + V+++ PF+PH +  LW+ 
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  784  LNGEGD-IDNAPWPVADESAMVEDSTLVVVQVNGKVRGKITVAVDATEEQVRERAGQEHL  842
            L + G+ I   PWP  DES +VE+   +VVQ++GKV++K+ VA D + E+++E A  ++ 
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  843  VAKYLDGKTVRKVIYVPGKLLNLVV  867
            V   + GK + KVI VP KL+N+V+
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVI  832

1438) leuS in NC_016800


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  522 bits (1969),  Expect = 5e-149, Method: Compositional matrix adjust.
 Identities = 350/737 (48%), Positives = 506/737 (69%), Gaps = 57/737 (7%)

Query  228  LVYRSHSMVNWCPGLGTVLANEEVTADGRSERGNFPVFRKKLSQWMMRITAYSdrliddl  287
            L Y ++  VNW   LGT +ANEEV +DG SERG +PV RK + QWM++ITAY++RL++DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  288  dlldwpdKVKSMQRNWIGRSRGAEVDFD--ALGHTITVFTTRPDTLFGASYMVLAPEHEL  345
            + +DWP+ +K MQRNWIG+S GA+V F     +  +TVFTTRPDTLFGA+Y VLAPEH L
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  346  VDALVAAGTNSYEGIDPRWTFGQATPAEAVKAYRASIAAKSDLERQE-NKEKTGVYLGVN  404
            VDA+ +++                  AEAV  Y+   + KSDL R +  KEKTGV  G  
Sbjct  268  VDAITTSD-----------------QAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSY  310

Query  405  AVNPVNGESIPVFIGDYVLTGYGTGAIMAVPAHDTRDYEFATEFGLPIREVVAGGNIAEA  464
            A+NPVNG  +PV I+DYVL++YGTGAIMAVPAHD RD EFA +F L I  V+ GGN+ EA
Sbjct  311  AINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEA  370

Query  465  AYTESGAAVNSANDQGLDINGLDKQEAIAQVIEWLVDKQKGSEKIQYKLRDWLFARQRYW  524
            A+TE G  +NS       ++GLDK  AIA+++EWL     G+E++ Y+LRDWLF+RQRYW
Sbjct  371  AFTEDGLHINSDF-----LDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYW  425

Query  525  GEPFPVVYDENGLAHALPESMLPVELPEVEDYKPVSFDPDDADSEPHPPLAKATEWTQVE  584
            GEP+P++  E+G + A+PES LP+ LP   D +P         +  ++PLA+ T+W +V 
Sbjct  426  GEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTDWLEVT  477

Query  585  LDLGDGLKKYTRDTNVMPQWAGSSWYQLRYIDPTNSEAFCDIENERYWTGPRSAEDSGGV  644
             +  DG+K   R+TN MPQWAGSSWY LRYIDP N+E + D E  + W           V
Sbjct  478  RE--DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLP---------V  525

Query  645  DLYVGGVEHAVLHLLYSRFWHKVLFDLGFVTSREPYRRLFNQGYIQAFAYTDSRGVYVPA  704
            D+YVGG EHAVLHLLY+RFWHKVL+DLG V ++EP+++LFNQG I + +Y DSRG  V++
Sbjct  526  DIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVAT  585

Query  705  EEVEEKDGKFYY--QGEEVNQEYGKMGKSLKNAVAPDDICRDFGADTLRVYEMAMGPLDT  762
            + VE +DG F+    GEE++Q  +KM+KSLKN V PDD+  ++GADTLRVYEM MGPLD+
Sbjct  586  DKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  763  SRPWSTKDVIGAHRFLQRLWRLVVSEDDGSIVVTDAALTDDDLKQLHRTIAGMRDDYEGL  822
            S +WS  ++ G+++FL+R+ RL+ + +     +T+      D K  + T+ ++ ++ + +
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLITTKE-----ITEENSGALD-KVYNETVKAVTEQVDQM  699

Query  823  RINTVVAKAIEYVNYLTKAYGSTGAPRAAVEPLVIMVAAVAPHIAEELWKRL-GHNDTIT  881
            ++NT +A+ + +VN   K              +V ++A+ APH++EELW+ L +  ++I+
Sbjct  700  KFNTAIAQLMVFVNAANKE---DKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESIS  756

Query  882  FVPFPEYEDKWLVDDEVEMPVQINGKVRARIMAPADASQDQISEIALASEAVATHIEGKN  941
            +VP P Y++  LV+++VE+ VQI+GKV+A+++ + D S++++ E+ALA+E V ++I GK+
Sbjct  757  YVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKD  816

Query  942  VIKKIVVPGRMVNLVVK  958
            +IK I VP ++VN+V+K
Sbjct  817  IIKVIAVPNKLVNIVIK  833


 Score =  140 bits (513),  Expect = 6e-34, Method: Compositional matrix adjust.
 Identities = 80/149 (54%), Positives = 104/149 (70%), Gaps = 10/149 (6%)

Query  25   GEIERSWQQYWIDNGTFNAPNPVGDLAVSGDKLPEDKLFVQDMFPYPSGAGLHVGHPLGY  84
              IE  WQ +W DN TF+          +G   +  K++  DMFPYPSGAGLHVGHP GY
Sbjct  7    TAIEPKWQAFWADNHTFK----------TGTDASKPKFYALDMFPYPSGAGLHVGHPEGY  56

Query  85   IATDVFARFNRMLGKNVLHTLGYDAFGLPAEQYAIQTGTHPRTTTMANIANMQRQLGALG  144
             ATD+++RF+R  G NVLH +G DAFGLPAEQYA++TG +P   T  NIAN +RQ+ ALG
Sbjct  57   TATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALG  116

Query  145  LGHDPRRSVATTDPEFYKWTQWIFLQIFN  173
            ++ D  R V TTDP++YKWTQWIF ++++
Sbjct  117  FSYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1439) leuS in NC_012660


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  522 bits (1969),  Expect = 5e-149, Method: Compositional matrix adjust.
 Identities = 360/875 (42%), Positives = 547/875 (63%), Gaps = 60/875 (6%)

Query  5    YQPREIENAAQSFWDEQKSFEVSEQPGKETFYCLSMFPYPSGK-LHMGHVRNYTIGDVIS  63
            Y+   IE   Q+FW ++ +F  + +++K  FY L MFPYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMQGKNVLQPMGWDAFGMPAENAAMKNNVAPAKWTYENIAYMKNQLRSLGLAVDWSR  123
            R++R QG NVL+PMGWDAFG+PAE+ AM     PA  T ENIA  K Q+ +LG++ DW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVTTCKPDYYRWEQWLFTRLFEKGVIYKKSGTVNWDPIDQTVLANEQVI-DGRGWRSGAL  182
            EV T  P+YY+W QW+FT+L+EKG+ Y     VNW     T +ANE+V+ DG + R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  IEKREIPMYYFKITAYADELLSSLDDLPGWPEQVKTMQRNWIGKSKGMEVQFPYNVDSIG  242
            + ++ +    +KITAYA+ LL  L+++ +WPE +K MQRNWIGKS G +V F  +V   +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTF--KVKDTD  240

Query  243  EAGALKVFTTRPDTLMGATYVAVAAEHPLATQAAQNNPELQAFIAECKGGSVAEADVA--  300
                + VFTTRPDTL GATY  +A+EH+L    A   ++    +A+ K  +   +D+A  
Sbjct  241  K--DFTVFTTRPDTLFGATYAVLAPEHALV--DAITTSDQAEAVADYKRQASLKSDLART  296

Query  301  --TQEKKGLPTGLFVEHPLTGEKLPVWVANYVLMHYGDGAVMAVPAHDERDFEFATKYSL  358
              ++EK G+ TG +  +P+ G  +PVW+A+YVL  YG GA+MAVPAHDERD EFA +++L
Sbjct  297  DLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNL  356

Query  359  PIKSVVRTSSGDTNPAPWQDAYGEHGELINSGEFDGLDFQGAFDAIEVALIKKNLGASRT  418
             I +V+  ++ +      + A+ E+G  INS+ +DGLD  +A+  +   L    +G    
Sbjct  357  DIIPVLEGGNVE------EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENV  410

Query  419  QFRLRDWGISRQRYWGCPIPIIHCESCGDVPVPEDQlpvvlpedvvpdGAG---SPLARM  475
             +RLRDW +SRQRYWG PIPIIH E     +VPE +LP+VLP       +G   SPLA +
Sbjct  411  TYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANV  470

Query  476  PEFYECSCPKCGQPAKRETDTMDTFVESSWYYARYASPHYEGGLVEKSAADHWLPVDQYI  535
             +  E +    G  ++RET+TM     SSWYY RY  PH    L +     +WLPVD Y+
Sbjct  471  TDWLEVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYV  529

Query  536  GGIEHAILHLLYARFFHKLMRDEGLVSSNEPFKNLLTQGMVVAETYYRREANGAYTWFNP  595
            GG EHA+LHLLYARF HK++ D G+V+++EPF++L+ QGM+++ +Y  R++ GA      
Sbjct  530  GGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY--RDSRGA------  581

Query  596  ADVELERDSKAKVISAKLIADGLPVEIG-GTEKMAKSKNNGVDPQSMIDQFGADTCRLFM  654
                L    K     + ++      E+  +  KM+KS +N V+P+ +++Q+GADT R++ 
Sbjct  582  ----LVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYE  637

Query  655  MFASPPDMSAEWSDSGVEGSHRFLKRVWRLAHA-HISQGLPGKLDVAALSDEQKLIRRSI  713
            MF +P D S  WS+ G+EGS++FL RV RL  + +I++  +G LD            +  
Sbjct  638  MFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALD------------KVY  685

Query  714  HLAIKQASQDVGQNHKFNTAIAQVMTLMNVLEKAPQA-TEQDRALVQEGLETVTLLLAPI  772
            + ++K  +++V+Q  KFNTAIAQ+M ++N  +K  +  ++  +++VQ        L+AP+
Sbjct  686  NETVKAVTEQVDQM-KFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQ--------LIAPF  736

Query  773  TPHISHDLWNRLGHSDAVID-ARWPVQDDSALVQDTLQLVIQVNGKLRGQIDMPATASRE  831
            +PH++++LW+ L  S+  I    WP  D+S LV++ +++V+Q++GK+++++ ++   SRE
Sbjct  737  APHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSRE  796

Query  832  DVEAAARVNENVLRFTEGLTIRKVIVVPGKLVNIV  866
            +++  A  NE+V     G  I KVI VP KLVNIV
Sbjct  797  ELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIV  831

1440) Mmc1_0432 in NC_008576


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  522 bits (1968),  Expect = 5e-149, Method: Compositional matrix adjust.
 Identities = 353/864 (41%), Positives = 546/864 (64%), Gaps = 43/864 (4%)

Query  5    YNPQAIESKWQKIWHQQKTFATPENLGDKETFYLLVMFPYPSGR-IHMGHVRNYAIGDVI  63
            Y+  AIE+KWQ +W ++ TF T  + + K  FY L MFPYPSG  +H+GH   Y+  D++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTD-ASKPKFYALDMFPYPSGAGLHVGHPEGYTATDIL  62

Query  64   ARYQRMQGKAVLHPMGWDAFGMPAENAAAQRKVHPRDWTYENIATMREELKSMGLSYDWD  123
            +R++R QG  VLHPMGWDAFG+PAE+ A +   +P + T ENIA  + +++++G+SYDWD
Sbjct  63   SRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWD  122

Query  124  REFATCDEDYAHAEQVLFLRLYEKGLVYRKHAFVNWDPVDHTVLANEQVI-DGCGWRSGA  182
            RE  T D +Y    Q +F +LYEKGL Y  +  VNW     T +ANE+V+ DG + R+G 
Sbjct  123  REVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGY  182

Query  183  PVEQRELNQWFFRITHYADELLDNLQHMDGWPETVRTMQTNWIGKSHGVEFAFALEGYPG  242
            PV ++ + QW ++IT YA+ LL++L+++D WPE+++ MQ NWIGKS G + +F + +   
Sbjct  183  PVVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDK  241

Query  243  TLPVYTTRPDTLMGVTFC--SvaaehpiaaavaennpaaaaFIK-TCQGVGTSEEALEKL  299
             + V+TTRPDTL G T+   +       A + +++  A A + + +    + +   L K 
Sbjct  242  DFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK-  300

Query  300  EKKGFDTGIKAIHPITGESLPVYIANFVLMSYGTGAVMAVPAHDQRDFEFAKKHGIEIKV  359
            EK G  TG  AI+P+ G  +PV IA++VL SYGTGA+MAVPAHD+RD EFAK+  ++I  
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  360  VIQPEGQTLHAEQLSEAYTGPGRLVNSGLFTGMDNEQAKQRVAEYFEAQGIGKGTINYRL  419
            V+  EG  ++      A+T  G  +NS+++ G+D+  A  ++ E +EA+G+G+  + YRL
Sbjct  361  VL--EGGNVEE----AAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRL  414

Query  420  RDWGISRQRYWGNPIPMVHCAACGvvpvpvAQLPIQLPNEVDFSEPG---NPLERHPSWK  476
            RDW +SRQRYWG+PIP++H       +VP ++LP+ LP   D+  +G   +PL     W 
Sbjct  415  RDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWL  474

Query  477  TCDCPQCGQPARRETDTMDTFMESSWYFLRYCSPHMGGVPLDKAAVDRWMPVNQYVGGIE  536
                 + G  +RRET+TM     SSWY+LRY  PH      D   + +W+PV+ YVGG E
Sbjct  475  EV-TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAE  533

Query  537  HAVLHLLYARFFHKALRDIGEVSCDEPFARLLTQGMVRKDTHRCAQHGWRYPKEVQERDG  596
            HAVLHLLYARF HK L D+G V+  EPF +L+ QGM+   + R ++ +      V+ RDG
Sbjct  534  HAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDG  593

Query  597  ALYCIECGGAVTVGRNEKMSKSKHNVVDPNDLIAGYGADTARLFMLFAAPADRDLEWNDS  656
            +++ +E G  +  +   KMSKS  NVV+P+D++  YGADT R++ +F +P D  + W++ 
Sbjct  594  SFFHVETGEELEQAPA-KMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEE  652

Query  657  GVDGAWRFLGRVWRLVLAAIERCGERQACTTTPADEQLKAFRSQLHNTIVKVTEDLNRQS  716
            G++G+++FL+RV RL+             T   ++E+  A+    ++T+  VTE++++  
Sbjct  653  GLEGSRKFLDRVYRLI------------TTKEITEENSGALDKVYNETVKAVTEQVDQMK  700

Query  717  FNTAIAAVMEMSNGAIATFKGEDRLTGEASALLWETAQVTVKLLHPYAPHMTEELWQRMG  776
            FNTAIA +M   N+A    + ED+L +       + A+  V+L+ P+APH+ EELWQ + 
Sbjct  701  FNTAIAQLMVFVNAA----NKEDKLFS-------DYAKGFVQLIAPFAPHLGEELWQALT  749

Query  777  EQS-LLSDTPWPLADAAALVKERVLIVIQVNGKLRSKLEVPVDMAQEAIEKLALADEHVK  835
              +  +S  PWP  D + LV + V IV+Q++GK+++KL V+ D+++E ++ +ALA+E V+
Sbjct  750  ASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQ  809

Query  836  VQTEGKTIRKVVVVPGRLVNIVAN  859
             +  GK I KV+ VP +LVNIV +
Sbjct  810  AEIAGKDIIKVIAVPNKLVNIVIK  833

1441) leuS in NC_011283


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  521 bits (1964),  Expect = 1e-148, Method: Compositional matrix adjust.
 Identities = 361/865 (42%), Positives = 551/865 (64%), Gaps = 46/865 (5%)

Query  5    YRPEEIESKVQLHWDENRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIA  63
            Y    IE+K Q  W +N+TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKTMQRNWIGRSEGVEISFDVNNYADK  242
            V RK + QW +KITAYA+ LL+DL+ +D WP+++K MQRNWIG+S G +++F V++    
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGCTY--LavaaghplaqqaaannpalaaFIDECR-NTKVAEADMATME  299
            +TV+TTRPDT+ G TY  LA   +   A  ++ +  A+A +  +   ++ +A +D+A  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGVDTGFKAIHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPV  359
            K GV TG  AI+P+ G E+PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L+I PV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  360  ILAADGSEPDLSAQALTEKGVLFNSGEFSGLDYEAGFNAIADKLAAMGVGERKINYRLRD  419
            + +++  E+     A+TE G+ +NS+ + GLD  +++  + + L A GVG+ ++ YRLRD
Sbjct  362  LEGGNVEEA-----AFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMVTLEDGTVLPTPEDQLPVILP--EDVVMDGIT-SPIKADPEWAKT  476
            W  SRQRYWG PIP++  EDGT  + PE +LP++LP   D+   G   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  T-VNGQPALRETDTFDTFMESSWYYARYTCPQYQEGMLDSKAANYWLPVDIYIGGIEHAI  535
            T  +G  + RET+T      SSWYY RY  P+  E + D    + WLPVDIY+GG EHA+
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVER  595
            +HLLY RF HK++ D G+V + EP ++L+ QGM+L+ ++      + R  + + D +  R
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEKR  591

Query  596  DEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMT  655
            D  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D +
Sbjct  592  D--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  656  LEWQESGVEGANRFLKRVWKLVYEHTTKGDVAALNVAALSEDQKALRRDIHKTIAKVTDD  715
            + W E G+EG+ +FL RV +L+    T  +++        E+  AL +  + T+  VT++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLI----TTKEITE-------ENSGALDKVYNETVKAVTEQ  695

Query  716  IGRRQTFNTAIAAIMELMNKLAKAPQEDEQDRALMQEALLAVVRMLNPFTPHASFTLWRE  775
            +++ + FNTAIA +M ++N         +++  L  +   + V+++ PF+PH +  LW+ 
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  776  LNGEGD-IDNAPWPVADESAMVEDSTLVVVQVNGKVRGKITVAVDATEEQVRERAGQEHL  834
            L + G+ I   PWP  DES +VE+   +VVQ++GKV++K+ VA D + E+++E A  ++ 
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  835  VAKYLDGKTVRKVIYVPGKLLNLVV  859
            V   + GK + KVI VP KL+N+V+
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVI  832

1442) Kvar_3692 in NC_013850


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  521 bits (1964),  Expect = 1e-148, Method: Compositional matrix adjust.
 Identities = 361/865 (42%), Positives = 551/865 (64%), Gaps = 46/865 (5%)

Query  5    YRPEEIESKVQLHWDENRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIA  63
            Y    IE+K Q  W +N+TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKTMQRNWIGRSEGVEISFDVNNYADK  242
            V RK + QW +KITAYA+ LL+DL+ +D WP+++K MQRNWIG+S G +++F V++    
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGCTY--LavaaghplaqqaaannpalaaFIDECR-NTKVAEADMATME  299
            +TV+TTRPDT+ G TY  LA   +   A  ++ +  A+A +  +   ++ +A +D+A  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGVDTGFKAIHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPV  359
            K GV TG  AI+P+ G E+PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L+I PV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  360  ILAADGSEPDLSAQALTEKGVLFNSGEFSGLDYEAGFNAIADKLAAMGVGERKINYRLRD  419
            + +++  E+     A+TE G+ +NS+ + GLD  +++  + + L A GVG+ ++ YRLRD
Sbjct  362  LEGGNVEEA-----AFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMVTLEDGTVLPTPEDQLPVILP--EDVVMDGIT-SPIKADPEWAKT  476
            W  SRQRYWG PIP++  EDGT  + PE +LP++LP   D+   G   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  T-VNGQPALRETDTFDTFMESSWYYARYTCPQYQEGMLDSKAANYWLPVDIYIGGIEHAI  535
            T  +G  + RET+T      SSWYY RY  P+  E + D    + WLPVDIY+GG EHA+
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVER  595
            +HLLY RF HK++ D G+V + EP ++L+ QGM+L+ ++      + R  + + D +  R
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEKR  591

Query  596  DEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMT  655
            D  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D +
Sbjct  592  D--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  656  LEWQESGVEGANRFLKRVWKLVYEHTTKGDVAALNVAALSEDQKALRRDIHKTIAKVTDD  715
            + W E G+EG+ +FL RV +L+    T  +++        E+  AL +  + T+  VT++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLI----TTKEITE-------ENSGALDKVYNETVKAVTEQ  695

Query  716  IGRRQTFNTAIAAIMELMNKLAKAPQEDEQDRALMQEALLAVVRMLNPFTPHASFTLWRE  775
            +++ + FNTAIA +M ++N         +++  L  +   + V+++ PF+PH +  LW+ 
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  776  LNGEGD-IDNAPWPVADESAMVEDSTLVVVQVNGKVRGKITVAVDATEEQVRERAGQEHL  834
            L + G+ I   PWP  DES +VE+   +VVQ++GKV++K+ VA D + E+++E A  ++ 
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  835  VAKYLDGKTVRKVIYVPGKLLNLVV  859
            V   + GK + KVI VP KL+N+V+
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVI  832

1443) Entas_1156 in NC_015968


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  521 bits (1964),  Expect = 1e-148, Method: Compositional matrix adjust.
 Identities = 350/865 (41%), Positives = 544/865 (63%), Gaps = 46/865 (5%)

Query  13   YRPEEIESKVQQHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIA  71
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  72   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSR  131
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  132  ELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  190
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  191  VERKEIPQWFIKITAYAdellndldnldHWPDTVKTMQRNWIGRSEGVEITFNVENYDQT  250
            V RK + QW +KITAYA E L +  +  +WP+++K MQRNWIG+S G ++TF+V + D+ 
Sbjct  184  VVRKPMRQWMLKITAYA-ERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  251  LTVYTTRPDTFMGATYLAVAAGHPLAQ--KAAENNPVLATFI-DECRTTKVAEADMATME  307
            +TV+TTRPDT+ GATY  +A+ H+L +   ++++   +A +  +    + +A +D+A  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  308  KKGVDTGFKAIHPLTGEAIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLAIKPV  367
            K GV TG  AI+P+ G  +PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L I PV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  368  ILAADGSEPDLSEQALTEKGTLFNSGEFSGLSFEEGFNAIADKLAAKGVGERKVNFRLRD  427
            + +++  E+ ++E++L  ++ +++     GL    ++  + + L A GVG+ +V +RLRD
Sbjct  362  LEGGNVEEAAFTEDGLHINSDFLD-----GLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  428  WGVSRQRYWGAPIPMVTLEDGTVLPTPEDQLPVILP--EDVVMDGIT-SPIKADPEWAKT  484
            W  SRQRYWG PIP++  EDGT  + PE +LP++LP   D+   G   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  485  T-VNGQPALRETDTFDTFMESSWYYARYTCPQYQDGMLDSKAANYWLPVDIYIGGIEHAI  543
            T  +G  + RET+T      SSWYY RY  P+  + + D    + WLPVDIY+GG EHA+
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  544  MHLLYFRFFHKLMRDAGLVNSDEPAKQLLCQGMVLADAFYYVGVNGERNWVSPKDAIVER  603
            +HLLY RF HK++ D G+V + EP ++L+ QGM+L+ ++      + R  + + D +  R
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEKR  591

Query  604  DEKGRIVKAKDGEGHELVYTGMSKMSKSKNNGIDPQEMVERYGADTVRLFMMFASPADMT  663
            D  G +     GE  E    + +KMSKS +N ++P+++VE+YGADT+R++ MF +P D +
Sbjct  592  D--GSFFHVETGEELE---QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  664  LEWQESGVEGANRFLKRVWKLVYEHTSQGDAPALNAAALSEDQQALRRDVHKTIAKVTDD  723
            + W E G+EG+ +FL RV +L+       + ++           AL +  + T+  VT++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLITTKEITEENSG-----------ALDKVYNETVKAVTEQ  695

Query  724  IGRRQTFNTAIAAIMELMNKLAKAPQEGEQDRALMREALLAVVRMLNPFTPHASFTLWHE  783
            +++ + FNTAIA +M ++N        ++++  L  +   + V+++ PF+PH +  LW+ 
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  784  LKGEGD-IDNAPWPVADESAMVENTTLVVVQVNGKVRGKITVAVDATEEQVRERAGQEHL  842
            L + G+ I   PWP  DES +VEN   +VVQ++GKV++K+ VA D + E+++E A  ++ 
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  843  VAKYLEGVTVRKVIYVPGKLLNLVV  867
            V   + G  + KVI VP KL+N+V+
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVI  832

1444) ENC_20680 in NC_021046


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  521 bits (1964),  Expect = 1e-148, Method: Compositional matrix adjust.
 Identities = 352/865 (41%), Positives = 547/865 (64%), Gaps = 46/865 (5%)

Query  5    YRPEEIESKVQQHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIA  63
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYAdellndldnldHWPDTVKTMQRNWIGRSEGVEITFNVENYDQT  242
            V RK + QW +KITAYA E L +  +  +WP+++K MQRNWIG+S G ++TF+V + D+ 
Sbjct  184  VVRKPMRQWMLKITAYA-ERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGATYLAVAAGHPLAQ--KAAENNPELATFI-DECRNTKVAEADMATME  299
            +TV+TTRPDT+ GATY  +A+ H+L +   ++++   +A +  +   ++ +A +D+A  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGVDTGFKAIHPLTGEAIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFATKYGLTIKPV  359
            K GV TG  AI+P+ G  +PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L I PV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  360  ILAADGSEPDLSEQALTEKGTLFNSGEFSGLSFEEGFNAIADKLASLGVGERKVNYRLRD  419
            + +++  E+ ++E++L  ++ +++     GL    ++  + + L + GVG+ +V YRLRD
Sbjct  362  LEGGNVEEAAFTEDGLHINSDFLD-----GLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMVTLEDGTVMPTPEDQLPVILP--EDVVMDGIT-SPIKADPEWAKT  476
            W  SRQRYWG PIP++  EDGT  + PE +LP++LP   D+   G   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  T-VNGQPALRETDTFDTFMESSWYYARYTCPQYKEGMLDSDAANYWLPVDIYIGGIEHAI  535
            T  +G  + RET+T      SSWYY RY  P+  E + D +  + WLPVDIY+GG EHA+
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLLYFRFFHKLMRDAGLVNSDEPAKQLLCQGMVLADAFYYVGANGERNWVSPVDAIVER  595
            +HLLY RF HK++ D G+V + EP ++L+ QGM+L+ +  Y ++ G    + + D +  R
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS--YRDSRGA---LVATDKVEKR  591

Query  596  DEKGRIVKAKDAEGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMT  655
            D  G +     +E  E    + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D +
Sbjct  592  D--GSFFHVETGEELE---QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  656  LEWQESGVEGANRFLKRVWKLVYEHTSQGDAPALNVAALSEDQQALRRDVHKTIAKVTDD  715
            + W E G+EG+ +FL RV +L+       + ++           AL +  + T+  VT++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLITTKEITEENSG-----------ALDKVYNETVKAVTEQ  695

Query  716  IGRRQTFNTAIAAIMELMNKLAKAPQDGEQDRALMREALLAVVRMLNPFTPHVSFTLWQE  775
            +++ + FNTAIA +M ++N        ++++  L  +   + V+++ PF+PH++  LWQ 
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  776  LKGEGD-IDNAPWPVADESAMVENTTLVVVQVNGKVRGKITVAVDATEEQVRERAGQEHL  834
            L + G+ I   PWP  DES +VEN   +VVQ++GKV++K+ VA D + E+++E A  ++ 
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  835  VAKYLEGVTVRKVIYVPGKLLNLVV  859
            V   + G  + KVI VP KL+N+V+
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVI  832

1445) leuS in NC_002939


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  521 bits (1967),  Expect = 6e-149, Method: Compositional matrix adjust.
 Identities = 365/858 (43%), Positives = 529/858 (62%), Gaps = 68/858 (7%)

Query  5    YIPKNVEGKWQEIWEENKTFTVTEDPSKPKYYLLEMFPYPSGR-IHMGHVRNYSIGDVVG  63
            Y    +E KWQ +W +N TF    D+SKPK+Y L+MFPYPSG  +H+GH   Y+  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RFKRMRGFNVLHPMGWDAFGMPAENAAIKHGSHPAKWTYENIDYMRSQLKKMGLSYDWGR  123
            RFKR +G NVLHPMGWDAFG+PAE+ A+  G++PA  T ENI   + Q++ +G+SYDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCDVDYYKWEQKMFLEMYEKGLVYKKSSFVNWCPACETVLANEQV-EDGCCWRCDSD  182
            E+ T D +YYKW Q +F  +YEKGL Y     VNW     T +ANE+V  DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VTQKELDQWFFRITRYAEELLEDTWNLPGWPERVLVMQRNWIGKSFGCEIDFPVEGKVEK  242
            V +K + QW ++IT YAE LLED  +  +WPE +  MQRNWIGKS G ++ F V +    
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDL-EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  VKVFTTRQDTLYGATFMSLAPEHPQALELTTPERRAEVEAFIDKVKKTDKIKRTAEDFEK  302
              VFTTR DTL+GAT+  LAPEH+    +TT+++   V  +  +      + RT    EK
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEK  302

Query  303  EGVFTGAYCINPVTNLRMPVYLANFVLLDYGTGAVMAVPTHDQRDFEFARTYDLPLQVVI  362
             GV TG+Y INPV    MPV +A++VL  YGTGA+MAVP+HD+RD EFA+ ++L +  V+
Sbjct  303  TGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL  362

Query  363  QPEGETLDPAAMTAAYTEVGTMVNSGPFNGMKSDEAKEKIADYLEQEGVGTKTVNYRLRD  422
              EG  ++     AA+TE G  +NS+ ++G+    A  K+ + LE EGVG   V YRLRD
Sbjct  363  --EGGNVE----EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  423  WGISRQRYWGNPIPVIN--CDICGvvpvpdkdlpvvlpMDAEFTGEGGNPLARVESFVNV  480
            W +SRQRYWG+PIP+I+   +    VP ++  L + +  D   +G G +PLA V   ++V
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  481  TCPQCGAEARRETDTMDTFVQSSWYFLRYCCPDFACGPIDRARAGYWMPVDQYIGGIEHA  540
            T  + G  +RRET+TM     SSWY+LRY  P+ +    D      W+PVD Y+GG EHA
Sbjct  477  TRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  541  VLHLLYSRFFTKALRDLGYVTVAEPFKNLLTQGMVI-------------------KDG--  579
            VLHLLY+RF  K L DLG V   EPF++L+ QGM++                   +DG  
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSF  595

Query  580  -------------AKMSKSKGNVVDPDALIERYGADTARLFTLFAAPPEKDLDWSDQGVE  626
                         AKMSKS  NVV+PD ++E+YGADT R++ +F +P +  + WS++G+E
Sbjct  596  FHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLE  655

Query  627  GSFRFLNRVWRLVFEVLPFIGSAGKPDPAALGDGARDLRRTVHKTIRKVTDDLDERFHFN  686
            GS +FL+RV RL+                   + +  L +  + T++ VT+++D+   FN
Sbjct  656  GSRKFLDRVYRLI------------TTKEITEENSGALDKVYNETVKAVTEQVDQ-MKFN  702

Query  687  TAISAVMELVNAIQSFEPKNAPENAPVLREAVESVVQLLAPFVPHVAEELWESLGHQG-G  745
            TAI+ +M +VNA        A  +  ++ +   + VQL+APF PH++EELW++L   G +
Sbjct  703  TAIAQLMVFVNA--------ANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGES  754

Query  746  VEASGWPSYDPEATVEEELLIVVQVNGKLRGKVTVAVDAGEEQvkaaafaddkvkPWLDG  805
            +    WPSYD    VE+++ IVVQ++GK+++K+ VA D + E+++  A+A++KV++ + G
Sbjct  755  ISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAG  814

Query  806  KQIRKAIYVPGKLLNIVV  823
            K+I K I VP KL+NIV+
Sbjct  815  KDIIKVIAVPNKLVNIVI  832

1446) leuS in NC_020127


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  521 bits (1967),  Expect = 6e-149, Method: Compositional matrix adjust.
 Identities = 343/851 (41%), Positives = 537/851 (64%), Gaps = 79/851 (9%)

Query  7    YDPNIIEKKWQRYWEEQHAYACDIDPNKKKYYVLEMWPYPSG-NIHMGHVRNYSIGDVIA  65
            YD   IE KWQ +W ++H++  + D++K K+Y L+M PYPSG  +H+GH   Y+  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  66   RIKRMQGYNVLHPMGWDAFGLPAELAAIKHHTQPADWTYTNINEMRAQLKRLGYSYDWQR  125
            R+KR QG NVLHPMGWDAFGLPAE  A+    +PA+ T  NI + + Q++ LG+SYDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  126  EIATCDPDYYQWEQLFFVDCFEKGLVYRKKAPQNWCPSCNTVLANEQVI-EGSCWRCDTS  184
            E+ T DP+YY+W Q +F   +EKGL Y    P NW     T +ANE+V+ +G+  R + +
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  185  IIQKELTQWFLKITDYAEELLDDLTTLKYSWPDRVITMQENWLGKSTGVEISFPIESSQD  244
            +++K + QW LKIT YAE LL+DL  +   WP+ +  MQ NW+GKSTG +++F +  ++ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV--DWPESIKDMQRNWIGKSTGANVTFKVKDTDK  241

Query  245  FITIFTTRPDTIFGATAIILAPEHPILETL-LNDTPQKEKLYNVIEKMRNMDRLERQSNL  303
             +T+FTTRPDT+FGAT  +LAPEH++++++  +D ++    Y+    +++   L R    
Sbjct  242  DFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKS--DLARTDLA  299

Query  304  LTKEGIFIDRYCINPCSGDKIPIWIGNFVLADYGTGAIMAVPAHDQRDFDFCKKYNLPIS  363
              K G+  + Y INP +G  +P+WI+++VLA YGTGAIMAVPAHD+RD +F K++NL I 
Sbjct  300  KEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDII  359

Query  364  IVIQPDELQINEHTIVEPWTGLGTLIHSGQFTGLTNKEAKEKITQYLEKIGKATRVVSWR  423
             V++ ++  ++E ++ E     G  I+S+ + GL +  A  K+ + LE  G +   V+ R
Sbjct  360  PVLEGGN--VEEAAFTED----GLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYR  413

Query  424  LRDWNISRQRYWGTPIPIIYCKNCGVVSVPKNELPVILP--TNITINEDGSSPLPQESSF  481
            LRDW +SRQRYWG PIPII   +    +VP +ELP++LP   +I  +  G SPL++ +  
Sbjct  414  LRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDW  473

Query  482  IDCMCPQCGGIAKRETDTMDTFVDSSWYFARFVDPKNTKQPFDTSIAKYWLNVDQYIGGV  541
            ++ +  + G  ++RET+TM    +SSWY+ R++DP NT +  D  + K WL VD Y+GG 
Sbjct  474  LE-VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGA  532

Query  542  EHAILHLLYSRFFTKLLRDLGYLPSNINEPFAKLLTQGMVI-------------------  582
            EHA+LHLLY+RF  K+L DLG +P+  +EPF KL+ QGM++                   
Sbjct  533  EHAVLHLLYARFWHKVLYDLGVVPT--KEPFQKLFNQGMILGTSYRDSRGALVATDKVEK  590

Query  583  KDGS---------------KMSKSKGNIVDPNQMINIYGADTIRLFCLFAAPPERDFDWS  627
            +DGS               KMSKS  N+V+P+++++ YGADT+R++ +F +P +  + WS
Sbjct  591  RDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWS  650

Query  628  DSGIEGSYRFLHRVWRLFIDVQPHIHTTHAGNSTVIETTTALTKDVKRKEHITIKKVSED  687
            + G+EGS +FL+RV RL+           + +    E + AL K  +     T+K V+E+
Sbjct  651  EEGLEGSRKFLDRVYRLI-----------TTKEITEENSGALDKVYNE----TVKAVTEQ  695

Query  688  IENKYQFNTAIASIMEFVNTLYLSKNELILTVEGKNILSSAIATVLTLLSPMTPHICEEL  747
            +++  +FNTAIA +M FVN+   +K++ +++  +K ++         L++P +PH+ EEL
Sbjct  696  VDQM-KFNTAIAQLMVFVNA--ANKEDKLFSDYAKGFVQ--------LIAPFAPHLGEEL  744

Query  748  WSYL-GHSTSISLEPWPKWDPQALLKDVVTIVVQINGKVRNKFEVPMDLSKEELEHIIFN  806
            W  L + + SIS  PWP  D   L+ + V IVVQI+GKV+ K+ V+ DLS+EEL+++ + 
Sbjct  745  WQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALA  804

Query  807  DTKITQYLEGK  817
            + K+   + GK
Sbjct  805  NEKVQAEIAGK  815

1447) leuS in NC_008011


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  521 bits (1967),  Expect = 6e-149, Method: Compositional matrix adjust.
 Identities = 343/851 (41%), Positives = 537/851 (64%), Gaps = 79/851 (9%)

Query  7    YDPNIIEKKWQRYWEEQHAYACDIDPNKKKYYVLEMWPYPSG-NIHMGHVRNYSIGDVIA  65
            YD   IE KWQ +W ++H++  + D++K K+Y L+M PYPSG  +H+GH   Y+  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  66   RIKRMQGYNVLHPMGWDAFGLPAELAAIKHHTQPADWTYTNINEMRAQLKRLGYSYDWQR  125
            R+KR QG NVLHPMGWDAFGLPAE  A+    +PA+ T  NI + + Q++ LG+SYDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  126  EIATCDPDYYQWEQLFFVDCFEKGLVYRKKAPQNWCPSCNTVLANEQVI-EGSCWRCDTS  184
            E+ T DP+YY+W Q +F   +EKGL Y    P NW     T +ANE+V+ +G+  R + +
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  185  IIQKELTQWFLKITDYAEELLDDLTTLKYSWPDRVITMQENWLGKSTGVEISFPIESSQD  244
            +++K + QW LKIT YAE LL+DL  +   WP+ +  MQ NW+GKSTG +++F +  ++ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV--DWPESIKDMQRNWIGKSTGANVTFKVKDTDK  241

Query  245  FITIFTTRPDTIFGATAIILAPEHPILETL-LNDTPQKEKLYNVIEKMRNMDRLERQSNL  303
             +T+FTTRPDT+FGAT  +LAPEH++++++  +D ++    Y+    +++   L R    
Sbjct  242  DFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKS--DLARTDLA  299

Query  304  LTKEGIFIDRYCINPCSGDKIPIWIGNFVLADYGTGAIMAVPAHDQRDFDFCKKYNLPIS  363
              K G+  + Y INP +G  +P+WI+++VLA YGTGAIMAVPAHD+RD +F K++NL I 
Sbjct  300  KEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDII  359

Query  364  IVIQPDELQINEHTIVEPWTGLGTLIHSGQFTGLTNKEAKEKITQYLEKIGKATRVVSWR  423
             V++ ++  ++E ++ E     G  I+S+ + GL +  A  K+ + LE  G +   V+ R
Sbjct  360  PVLEGGN--VEEAAFTED----GLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYR  413

Query  424  LRDWNISRQRYWGTPIPIIYCKNCGVVSVPKNELPVILP--TNITINEDGSSPLPQESSF  481
            LRDW +SRQRYWG PIPII   +    +VP +ELP++LP   +I  +  G SPL++ +  
Sbjct  414  LRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDW  473

Query  482  IDCMCPQCGGIAKRETDTMDTFVDSSWYFARFVDPKNTKQPFDTSIAKYWLNVDQYIGGV  541
            ++ +  + G  ++RET+TM    +SSWY+ R++DP NT +  D  + K WL VD Y+GG 
Sbjct  474  LE-VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGA  532

Query  542  EHAILHLLYSRFFTKLLRDLGYLPSNINEPFAKLLTQGMVI-------------------  582
            EHA+LHLLY+RF  K+L DLG +P+  +EPF KL+ QGM++                   
Sbjct  533  EHAVLHLLYARFWHKVLYDLGVVPT--KEPFQKLFNQGMILGTSYRDSRGALVATDKVEK  590

Query  583  KDGS---------------KMSKSKGNIVDPNQMINIYGADTIRLFCLFAAPPERDFDWS  627
            +DGS               KMSKS  N+V+P+++++ YGADT+R++ +F +P +  + WS
Sbjct  591  RDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWS  650

Query  628  DSGIEGSYRFLHRVWRLFIDVQPHIHTTHAGNSTVIETTTALTKDVKRKEHITIKKVSED  687
            + G+EGS +FL+RV RL+           + +    E + AL K  +     T+K V+E+
Sbjct  651  EEGLEGSRKFLDRVYRLI-----------TTKEITEENSGALDKVYNE----TVKAVTEQ  695

Query  688  IENKYQFNTAIASIMEFVNTLYLSKNELILTVEGKNILSSAIATVLTLLSPMTPHICEEL  747
            +++  +FNTAIA +M FVN+   +K++ +++  +K ++         L++P +PH+ EEL
Sbjct  696  VDQM-KFNTAIAQLMVFVNA--ANKEDKLFSDYAKGFVQ--------LIAPFAPHLGEEL  744

Query  748  WSYL-GHSTSISLEPWPKWDPQALLKDVVTIVVQINGKVRNKFEVPMDLSKEELEHIIFN  806
            W  L + + SIS  PWP  D   L+ + V IVVQI+GKV+ K+ V+ DLS+EEL+++ + 
Sbjct  745  WQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALA  804

Query  807  DTKITQYLEGK  817
            + K+   + GK
Sbjct  805  NEKVQAEIAGK  815

1448) leuS in NC_017540


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  521 bits (1966),  Expect = 7e-149, Method: Compositional matrix adjust.
 Identities = 363/865 (42%), Positives = 549/865 (64%), Gaps = 46/865 (5%)

Query  5    YRPEEIESKVQLHWDENRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIA  63
            Y    IE+K Q  W +N+TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKTMQRNWIGRSEGVEISFDVNDYADK  242
            V RK + QW +KITAYA+ LL+DL+ +D WP+++K MQRNWIG+S G +++F V+D    
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGCTY--LavaaghplaqqaaannpalaaFIDECR-NTKVAEADMATME  299
            +TV+TTRPDT+ G TY  LA   +   A  ++ +  A+A +  +   ++ +A +D+A  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGVDTGFKAIHPLTGEQIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPV  359
            K GV TG  AI+P+ G ++PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L+I PV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  360  ILAADGSEPDLSEQALTEKGVLFNSGEFSGLDYEAGFNAIADKLAAMGVGERKVNYRLRD  419
            +        ++ E A+TE G+ +NS+ + GLD  +++  + + L A GVG+ +V YRLRD
Sbjct  362  L-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMVTLEDGTVLPTPEDQLPVILP--EDVVMDGIT-SPIKADPEWAKT  476
            W  SRQRYWG PIP++  EDGT  + PE +LP++LP   D+   G   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  TVNDQ-PALRETDTFDTFMESSWYYARYTCPQYQEGMLDSKAANYWLPVDIYIGGIEHAI  535
            T +D   + RET+T      SSWYY RY  P+  E + D    + WLPVDIY+GG EHA+
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVER  595
            +HLLY RF HK++ D G+V + EP ++L+ QGM+L+ ++      + R  + + D +  R
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEKR  591

Query  596  DEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMT  655
            D  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D +
Sbjct  592  D--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  656  LEWQESGVEGANRFLKRVWKLVYEHTTKGEVAALNVAALSEDQKALRRDIHKTIAKVTDD  715
            + W E G+EG+ +FL RV +L+    T  E++        E+  AL +  + T+  VT++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLI----TTKEITE-------ENSGALDKVYNETVKAVTEQ  695

Query  716  IGRRQTFNTAIAAIMELMNKLAKAPQEDEQDRALMQEALLAVVRMLNPFTPHASFTLWRE  775
            +++ + FNTAIA +M ++N         +++  L  +   + V+++ PF+PH +  LW+ 
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  776  LNGEGD-IDNAPWPVADESAMVEDSTLVVVQVNGKVRGKITVAVDATEEQVRERAGQEHL  834
            L + G+ I   PWP  DES +VE+   +VVQ++GKV++K+ VA D + E+++E A  ++ 
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  835  VAKYLDGKTVRKVIYVPGKLLNLVV  859
            V   + GK + KVI VP KL+N+V+
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVI  832

1449) leuS in NC_012522


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  521 bits (1965),  Expect = 9e-149, Method: Compositional matrix adjust.
 Identities = 353/738 (48%), Positives = 501/738 (68%), Gaps = 65/738 (8%)

Query  220  LVYHSDSMVNWCPGLGTVLANEEVTADGRSDRGNFPVFRKHLQQWMMRITAYSDRLVDDL  279
            L Y+++  VNW   LGT +ANEEV +DG S+RG +PV RK ++QWM++ITAY++RL++DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  280  EYLDWPEKVKTMQRNWIGRSHGAQVRFDANG--HGIEVFTTRPDTLFGATYVTLAPEHEL  337
            E +DWPE +K MQRNWIG+S GA+V F  ++   ++ VFTTRPDTLFGATY  LAPEH L
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  338  VDEIVAAAWPEGVDARWTGGAATPGEAVAAYRKSIAAKSDLERQEY-KEKTGVFLGTYAV  396
            VD I ++                 +EAVA Y++  + KSDL R +  KEKTGV  G+YA+
Sbjct  268  VDAITTSD---------------QAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAI  312

Query  397  NPVNGHKLPVFIADYVLTGYGTGAIMAVPGHDHRDYEFATEFGLDIVEVISGGDLSKDAY  456
            NPVNG  +PV IADYVL++YGTGAIMAVP+HD+RD EFA +F LDI+ V+ GG++   A+
Sbjct  313  NPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEAAF  372

Query  457  TGDGTIVNSDFLNGMSVTDAKKAITDRLEADGTGKGTIQYKLRDWLFARQRYWGEPFPIV  516
            T DG  +NSDFL+G+  + A   + ++LEA+G G+  + Y+LRDWLF+RQRYWGEP+PI+
Sbjct  373  TEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPII  432

Query  517  YDADGNAHALPESALPVELPEVEDYAPVsfdpddassepsppLAKAVDWVNVELDLGDGL  576
               DG + A+PES LP+ LP   D  P        S+   +PLA+  DW++V  +  DG+
Sbjct  433  HWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTDWLEVTRE--DGV  482

Query  577  QTYRRDTNVMPQWAGSSWYQLRYIDPTNPDVFCDKENERYWTGPRPEIHGPNDPGGVDLY  636
            +  RR+TN MPQWAGSSWY LRYIDP N + + D E  + W               VD+Y
Sbjct  483  KG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWL-------------PVDIY  528

Query  637  VGGVEHAVLHLLYSRFWHKVLFDLGYVSSSEPYRRLYNQGYIQAYAYTDARGVYVPADEV  696
            VGG EHAVLHLLY+RFWHKVL+DLG V++ EP+++L+NQG I + +Y D+RG  V++D V
Sbjct  529  VGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKV  588

Query  697  EEKDGKFFH--QGAEVNREYGKMGKSLKNSVSPDDICEEYGADTLRVYEMSMGPLDTSRP  754
            E +DG FFH   G E+++  +KM+KSLKN V+PDD+ E+YGADTLRVYEM MGPLD+S +
Sbjct  589  EKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIA  648

Query  755  WATKDVVGAQRFLQRAWRVVVDEESGAVRVTDDAPTEDTLRALNKAIAGVGEDYTALRDN  814
            W+  ++ G+++FL+R  R++   E     +T++ +     +  N ++ +V E+   ++ N
Sbjct  649  WSEEGLEGSRKFLDRVYRLITTKE-----ITEENSGALD-KVYNETVKAVTEQVDQMKFN  702

Query  815  TAAAKLIEYTN------HLTKAYPAGAPRSAVeplvlmlaplaphlaeelWSRL-GHEKS  867
            TA A+L+ + N       L   Y+ G  +        ++AP+APHL+EELW  L +   S
Sbjct  703  TAIAQLMVFVNAANKEDKLFSDYAKGFVQ--------LIAPFAPHLGEELWQALTASGES  754

Query  868  LAHGPFPVAEEKWLVEDTVEYPIQVNGKVRSRVTVAADAPREEIEKIALADDKIVALLDG  927
            ++  P P  +E  LVE+ VE  +Q++GKV++++ VA D +REE++ +ALA++K+ A + G
Sbjct  755  ISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAG  814

Query  928  KDPRKVIVVPGKMVNIVL  945
            KD  KVI VP K+VNIV+
Sbjct  815  KDIIKVIAVPNKLVNIVI  832


 Score =  132 bits (486),  Expect = 8e-32, Method: Compositional matrix adjust.
 Identities = 74/144 (52%), Positives = 101/144 (71%), Gaps = 7/144 (4%)

Query  27   IEQRWQDRWSEEGTFDAPNPVGPLAGDVPADKLFVQDMFPYPSGTGLHVGHPLGYIATDV  86
            IE +WQ  W+++ TF +       + D +  K++  DMFPYPSG+GLHVGHP GY ATD+
Sbjct  9    IEPKWQAFWADNHTFKT-------GTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDI  61

Query  87   FARYHRMQGHNVLHTLGYDAFGLPAEQYAVQTGTHPRTTTEANIGNMKRQLRRLGLGHDE  146
            ++R+ R QGHNVLH +G DAFGLPAEQYA++TG +P   T  NI+N KRQ+  LG++ D 
Sbjct  62   LSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDW  121

Query  147  RRTFATTDVDFYHWTQWIFLQIHD  170
             R   TTD ++Y WTQWIF ++ +
Sbjct  122  DREVNTTDPNYYKWTQWIFTKLYE  145

1450) leuS in NC_017454


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  520 bits (1962),  Expect = 1e-148, Method: Compositional matrix adjust.
 Identities = 365/858 (43%), Positives = 528/858 (62%), Gaps = 68/858 (7%)

Query  5    YIPKNVEGKWQEIWDKNKTFTVTEDPSKPKYYLLEMFPYPSGR-IHMGHVRNYSIGDVVG  63
            Y    +E KWQ +W  N TF    D+SKPK+Y L+MFPYPSG  +H+GH   Y+  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RFKRMRGFNVLHPMGWDAFGMPAENAAIKHGSHPAKWTYENIDYMRSQLKKMGLSYDWGR  123
            RFKR +G NVLHPMGWDAFG+PAE+ A+  G++PA  T ENI   + Q++ +G+SYDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCDVDYYKWEQKMFLEMYEKGLVYKKSSFVNWCPACETVLANEQV-EDGCCWRCDSD  182
            E+ T D +YYKW Q +F  +YEKGL Y     VNW     T +ANE+V  DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VTQKELDQWFFRITRYAEELLEDTWNLPGWPERVLVMQRNWIGKSFGCEIDFPVEGKVEK  242
            V +K + QW ++IT YAE LLED  +  +WPE +  MQRNWIGKS G ++ F V +    
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDL-EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  VKVFTTRQDTLYGATFMSLAPEHPQALELTTPERRAEVEAFIDKVKKTDKIKRTAEDFEK  302
              VFTTR DTL+GAT+  LAPEH+    +TT+++   V  +  +      + RT    EK
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEK  302

Query  303  EGVFTGAYCINPVTNLRMPVYLANFVLLDYGTGAVMAVPTHDQRDFEFARTYDLPLQVVI  362
             GV TG+Y INPV    MPV +A++VL  YGTGA+MAVP+HD+RD EFA+ ++L +  V+
Sbjct  303  TGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL  362

Query  363  QPEGETLDPAAMTAAYTEVGTMVNSGPFNGMKSDEAKEKIADYLEQEGVGTKTVNYRLRD  422
              EG  ++     AA+TE G  +NS+ ++G+    A  K+ + LE EGVG   V YRLRD
Sbjct  363  --EGGNVE----EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  423  WGISRQRYWGNPIPVIN--CDICGvvpvpdkdlpvvlpMDAEFTGEGGNPLARVESFVNV  480
            W +SRQRYWG+PIP+I+   +    VP ++  L + +  D   +G G +PLA V   ++V
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  481  TCPQCGAEARRETDTMDTFVQSSWYFLRYCCPDFACGPIDRARAGYWMPVDQYIGGIEHA  540
            T  + G  +RRET+TM     SSWY+LRY  P+ +    D      W+PVD Y+GG EHA
Sbjct  477  TRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  541  VLHLLYSRFFTKALRDLGYVTVAEPFKNLLTQGMVI-------------------KDG--  579
            VLHLLY+RF  K L DLG V   EPF++L+ QGM++                   +DG  
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSF  595

Query  580  -------------AKMSKSKGNVVDPDALIERYGADTARLFTLFAAPPEKDLDWSDQGVE  626
                         AKMSKS  NVV+PD ++E+YGADT R++ +F +P +  + WS++G+E
Sbjct  596  FHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLE  655

Query  627  GSFRFLNRVWRLVFEVLPFIGSAGKPDPAALGDGARDLRRTVHKTIRKVTDDLDERFHFN  686
            GS +FL+RV RL+                   + +  L +  + T++ VT+++D+   FN
Sbjct  656  GSRKFLDRVYRLI------------TTKEITEENSGALDKVYNETVKAVTEQVDQ-MKFN  702

Query  687  TAISAVMELVNAIQSFEPKNAPENAPVLREAVESVVQLLAPFVPHVAEELWESLGHQG-G  745
            TAI+ +M +VNA        A  +  ++ +   + VQL+APF PH++EELW++L   G +
Sbjct  703  TAIAQLMVFVNA--------ANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGES  754

Query  746  VEASGWPSYDPEATVEEELLIVVQVNGKLRGKVTVAVDAGEEQvkaaafaddkvkPWLDG  805
            +    WPSYD    VE+++ IVVQ++GK+++K+ VA D + E+++  A+A++KV++ + G
Sbjct  755  ISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAG  814

Query  806  KQIRKAIYVPGKLLNIVV  823
            K+I K I VP KL+NIV+
Sbjct  815  KDIIKVIAVPNKLVNIVI  832

1451) leuS in NC_008578


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  520 bits (1963),  Expect = 1e-148, Method: Compositional matrix adjust.
 Identities = 354/852 (42%), Positives = 527/852 (62%), Gaps = 59/852 (6%)

Query  18   IYDFAAIQARWLPVWTELDPFRASDDPSDPRERRYMLDMFPYPSG-DLHMGHAEAFAIGD  76
            +YD +AI+++W + W++ + F+++ D+S P+   Y LDMFPYPSG +LH+GH+E+++  D
Sbjct  3    FYDHTAIEPKWQAFWADNHTFKTGTDASKPK--FYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  77   VVARYWFQRGYNVLHPIGWDAFGLPAENAAIQRNLHPADWTYRNIETQAASFRNYAISFD  136
            +++R+   +G NVLHP+GWDAFGLPAE+ A++   +PA+ T  NI      +   ++S+D
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  137  WSRRLHTCDPEYYKWTQWLFLRLFERGLAYRKASPVNWCPNDQTVLANEQVV-GGTCERC  195
            W R ++T DP+YYKWTQW+F +L+E+GLAY    PVNW  +  T +ANE+V+ +GT ER 
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  196  GAQVTKKTLTQWYFRITEYAQRLLDDMALLEGRWPERVLTMQRNWIGRSEGAYVDFTIEG  255
            G  V +K + QW ++IT YA+RLL+D+  ++  WPE +  MQRNWIG+S GA V F + +
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVD--WPESIKDMQRNWIGKSTGANVTFKVKD  238

Query  256  RAEPVTVFTTRPDTLYGATFFVIAADSPLAAEICAPEQRAAFEAYVDQVRRLSDIDRLST  315
                 TVFTTRPDTL+GAT+ V+A++ +L   I +++Q  A   Y  Q    SD+ R   
Sbjct  239  TDKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDL  298

Query  316  ERQKTGVFLGRYAVNPVNGERIPVWAADYVLADYGTGAIMAVPAHDQRDLDFALTYGLPV  375
             ++KTGV  G YA+NPVNG  +PVW ADYVLA YGTGAIMAVPAHD+RD +FA  + L +
Sbjct  299  AKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDI  358

Query  376  RVVVDTGEGDPAVTGVATEGDGVHINSGLIDGTDKAEGIARITRYLEDIGKGRAGVTYRL  435
              V++ G+    V   A   DG+HINS+++DG DKA +IA++   LE  G G   VTYRL
Sbjct  359  IPVLEGGN----VEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRL  414

Query  436  RDWLVSRQRFWGAPIPIVHCPGCGEvavpdqdlpvllpdlRGADLAPKGISPLAGAADWV  495
            RDWL SRQR+WG PIPI+H  +    AVP+ +LP++LP  ++   +  G SPLA  +DW+
Sbjct  415  RDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWL  474

Query  496  QTTCPRCGGSAQRDTDTMDTFVDSSWYYLRYCSPHDPSQPFDVAKVRQWLPVHQYVGGVE  555
            + T    G  ++R+T+TM    +SSWYYLRY  PH+  +  D   ++QWLPV+ YVGG E
Sbjct  475  EVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAE  533

Query  556  HAILHLLYSRFITKVLHDMGLVDFVEPFSALLNQGQVINQG-------------------  596
            HA+LHLLY+RF  KVL D+G+V   EPF  L+NQG ++  +                   
Sbjct  534  HAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDG  593

Query  597  ---------------KAMSKSLGNGVDLGEQLATYGVDAVRLTMVFAGPPEEDIDWADMN  641
                             MSKSL N V+ ++ +  YG D++R+  +F GP +  I W++  
Sbjct  594  SFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEG  653

Query  642  PGALGKFLARVWRIAGEVTSPVGAPPKDGDPALRRVTHRTIREVTELVESFRFNVAVARV  701
              +  KFL RV R+             +   AL +V + T++ VTE V+  +FN A+A++
Sbjct  654  LEGSRKFLDRVYRLI-----TTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQL  708

Query  702  MELANALRKAIDTGPGPADPAVREGAEALAVMLSLFAPYTAEECWARL-GHQPTVAKAGW  760
            M + NA  K         D    + A ++  +++ FAP  +EE W  L +   +++   W
Sbjct  709  MVFVNAANK--------EDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPW  760

Query  761  PTPDPELLAQEEVTCVVQVNGKVRERLRVSPSISeeelraaalaapavekaIDGRPVQRI  820
            P+ D   L +++V  VVQ++GKV+ +L V+  +S EEL+  ALA   V+  I G+ + ++
Sbjct  761  PSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKV  820

Query  821  IVRAPKLVNVVV  832
            I  + KLVN+V+
Sbjct  821  IAVPNKLVNIVI  832

1452) leuS in NC_021232


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  520 bits (1963),  Expect = 1e-148, Method: Compositional matrix adjust.
 Identities = 362/865 (42%), Positives = 548/865 (64%), Gaps = 46/865 (5%)

Query  5    YRPEEIESKVQLHWDENRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIA  63
            Y    IE+K Q  W +N+TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKTMQRNWIGRSEGVEISFDVNDYADK  242
            V RK + QW +KITAYA+ LL+DL+ +D WP+++K MQRNWIG+S G +++F V+D    
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGCTY--LavaaghplaqqaaannpalaaFIDECR-NTKVAEADMATME  299
            +TV+TTRPDT+ G TY  LA   +   A  ++ +  A+A +  +   ++ +A +D+A  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGVDTGFKAIHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPV  359
            K GV TG  AI+P+ G E+PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L+I PV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  360  ILAADGSEPDLSEQALTEKGVLFNSGEFSGLDYEAGFNAIADKLAAMGVGERKVNYRLRD  419
            +        ++ E A+TE G+ +NS+ + GLD  +++  + + L A GVG+ +V YRLRD
Sbjct  362  L-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMVTLEDGTVLPTPEDQLPVILP---EYVVMDGITSPIKADPEWAKT  476
            W  SRQRYWG PIP++  EDGT  + PE +LP++LP   +    +   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  T-VNGQPALRETDTFDTFMESSWYYARYTCPQYQEGMLDSKAANYWLPVDIYIGGIEHAI  535
            T  +G  + RET+T      SSWYY RY  P+  E + D    + WLPVDIY+GG EHA+
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVER  595
            +HLLY RF HK++ D G+V + EP ++L+ QGM+L+ ++      + R  + + D +  R
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEKR  591

Query  596  DEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMT  655
            D  G +      +G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D +
Sbjct  592  D--GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  656  LEWQESGVEGANRFLKRVWKLVYEHTTKGEVAALNVAALSEDQKALRRDIHKTIAKVTDD  715
            + W E G+EG+ +FL RV +L+    T  E++        E+  AL +  + T+  VT++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLI----TTKEITE-------ENSGALDKVYNETVKAVTEQ  695

Query  716  IGRRQTFNTAIAAIMELMNKLAKAPQEDEQDRALMQEALLAVVRMLNPFTPHASFTLWRE  775
            +++ + FNTAIA +M ++N         +++  L  +   + V+++ PF+PH +  LW+ 
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  776  LNGEGD-IDNAPWPVADESAMVEDSTLVVVQVNGKVRGKITVAVDATEEQVRERAGQEHL  834
            L + G+ I   PWP  DES +VE+   +VVQ++GKV++K+ VA D + E+++E A  ++ 
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  835  VAKYLDGKTVRKVIYVPGKLLNLVV  859
            V   + GK + KVI VP KL+N+V+
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVI  832

1453) MU9_1349 in NC_020418


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  520 bits (1963),  Expect = 1e-148, Method: Compositional matrix adjust.
 Identities = 349/867 (41%), Positives = 542/867 (63%), Gaps = 50/867 (5%)

Query  5    YRPEDIEQQVQSHWQEKQTFKVTEDNSKEKYYCLSMLPYPSGR-LHMGHVRNYTLGDVMS  63
            Y    IE + Q+ W +++TFK   D SK K+Y L M+PYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYANIEYMKQQLKKLGFAYDWDR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T  NI   K+Q++ LGF+YDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVTTCTPEYYRWEQWFFTKLYEKGLAYKKTSAVNWCPHDLTVLANEQVI-DGCCWRCDTP  182
            EV T  P+YY+W QW+FTKLYEKGLAY    +VNW  +  T +ANE+V+ DG   R + P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYAeellndldtledWPEQVKTMQRNWIGRSEGVEITFDVADSTEK  242
            V RK + QW +KITAYA E L +     DWPE +K MQRNWIG+S G ++TF V D+   
Sbjct  184  VVRKPMRQWMLKITAYA-ERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LSVYTTRPDTFMGVTYLAVAAGHPLAQQAAQNNPELKTFIDECRNTKVAEAEMA----TM  298
            ++V+TTRPDT+ G TY  +A+ H+L +  + ++      + + +      +++A    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQA--EAVADYKRQASLKSDLARTDLAK  300

Query  299  EKKGVATGMFAIHPLTGEKVAVWVANFVLMEYGTGAVMAVPAHDQRDWEFATKYGLPIKP  358
            EK GV TG +AI+P+ G  ++VW+A++VL  YGTGA+MAVPAHD+RDWEFA ++ L I P
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VILGEDGNAPDISEAAMTGKNTLFNSGEFDGLDYTAGFNAIADKLVALGVGERKVNYRLR  418
            V+ G + + + ++E ++  ++ +     +DGLD ++++  + + L A GVG+ +V YRLR
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDF-----LDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  419  DWGVSRQRYWGAPIPMATLEDGTVVPVPEDQLPVILP--EDVVMDGIT-SPIKADPEWAK  475
            DW  SRQRYWG PIP+   EDGT  +VPE +LP++LP   D+   G   SP+    +W  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  476  TT-INGQPALRETDTFDTFMESSWYYARYCCPDYDKGMLDPAAANYWLPVDQYIGGIEHA  534
             T  +G  + RET+T      SSWYY RY  P+    + D    + WLPVD Y+GG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  535  IMHLMYFRFFHKLMRDAGLVNSNEPAKNLLCQGMVLADSFYYTDTDGHRVWVSPEDAILE  594
            ++HL+Y RF HK++ D G+V ++EP ++L+ QGM+L+ S  Y D+ G  V   + D +  
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS--YRDSRGALV---ATDKVEK  590

Query  595  RDDKNRIIKATDKEGRELVHTGMSKMSKSKNNGVDPQIMVEKYGADTVRLFMMFAAPPEL  654
            RD+    + +    G EL ++  +KMSKS +N V+P+ +VE+YGADT+R++ MF +P + 
Sbjct  591  RDGSFFHVET----GEELEQAP-AKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  655  TLEWQESGVEGANRFIRRVWRLV-YEHVQKGKTAPLDISSLTPEQKDLRRSLHKTIAKVS  713
            ++ W E G+EG+ +F+ RV RL+   ++   ++++LD            +  + T+  V+
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALD------------KVYNETVKAVT  693

Query  714  DDAGRRKQFNTAIAAIMELLNELQRAPQETEQDRALMQEALDAVIRMLSPIIPHAGFTLW  773
            ++ ++ K FNTAIA +M ++N        ++++  L  +   + +++++P+ PH G  LW
Sbjct  694  EQVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELW  745

Query  774  KALGHETD-VDDAQWPVASEEAMIDDTKLIVIQINGKVRGRITVAADAEQDAVMALASQE  832
            +AL    + +    WP   E  ++++   IV+QI+GKV++++ VA D  ++ +  +A  +
Sbjct  746  QALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALAN  805

Query  833  ANVAKYLEGVSVRKVIYVPGKLLNLVV  859
             +V   + G  + KVI VP KL+N+V+
Sbjct  806  EKVQAEIAGKDIIKVIAVPNKLVNIVI  832

1454) leuS in NC_009091


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  520 bits (1962),  Expect = 1e-148, Method: Compositional matrix adjust.
 Identities = 344/858 (41%), Positives = 551/858 (65%), Gaps = 41/858 (4%)

Query  13   NLYNPSEIEKKWQSIWTENNLYKTDELTDNSDKFYALSMFPYPSG-NLHMGHVRNYVITD  71
             +Y+ + IE KWQ++W++N+ +KT+    +  KFYAL MFPYPSG  LH+GH   Y  TD
Sbjct  2    TFYDHTAIEPKWQAFWADNHTFKTGT-DASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  72   LIARFQRFKGKSVLHPMGWDAFGLPAENAAIERGISPSVWTKKNISHMKSQLKLLGLSVD  131
            +++RF+R +G +VLHPMGWDAFGLPAE+ A++ G  P+  T  NI++ K Q++ LG+S D
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  132  WDREFATCDENYYVWTQYLFLELYKAGLVYQKESEVNWDPIDNTVLANEQVDSEGKSWRS  191
            WDRE  T D NYY WTQ +F  LY  GL Y+ E  VNW     T +ANE+V ++G S R+
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  192  GAIVEKKLLKQWFLRITNYAdellkdlekldNWPERVKIMQDNWIGKSIGTNINFNINTH  251
            G  V +K ++QW L+IT YA E L +     +WPE +K MQ NWIGKS G+N+ F+++ +
Sbjct  181  GYPVVRKPMRQWMLKITAYA-ERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVK-D  238

Query  252  PEKKLTVFTTRPDTLFGVTYLAISVNHSLIKNISDQETIQHienlkkylkknknneleki  311
             +K +TVFTTRPDTLFG TY  ++ +H+L+  I+  +  + + + K+    + +     +
Sbjct  239  TDKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDL  298

Query  312  gikTSLI-----AINPVNSEPIPIWVASYVLDEYGTGAVMGVPAHDLRDFEFAKKNNIDI  366
            +   + +     AINPVN+  +P+W+A YVL  YGTGA+M+VPAHD RD EFAK+ N+DI
Sbjct  299  AKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDI  358

Query  367  KQVIIKDKSEQNKELDEAYVENGYLINSNQYDGV--ANTIAKLK--ISEEGVNNRWAENK  422
              V+  ++ E     + A+ E+G  INS+  DG+  A++IAK+   +  EGV N    ++
Sbjct  359  IPVLEGGNVE-----EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGN----EN  409

Query  423  TQYRLRDWLISRQRYWGCPIPIVNCKKCGSVPLNQSELPVALP--KDIDISANKINALGD  480
              YRLRDWL+SRQRYWG PIPI++     S ++ +SELP+ LP  KDI  S+   ++L++
Sbjct  410  VTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLAN  469

Query  481  NKNWVNTTCPKCGIAAKKETDTMDTFMCSSWYFLRYPSSKCPNKPFEKIEINKWLPVDQY  540
              +W++ T    G+ +++ET+TM     SSWY+LRY  +   +K  +   +++WLPVD Y
Sbjct  470  VTDWLEVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIY  528

Query  541  VGGVEHAILHLLYARFFTKALRDNQLFEIDEPFKKLLTQGMVQAAAYKNNKTGKYVSPSD  600
            VGG EHA+LHLLYARF  K L D  +    EPF+KL+ QGM+ +++Y++++ G  V+   
Sbjct  529  VGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSR-GALVATDK  587

Query  601  INDLSNPTDPIDNT-KLEILFEKMSKSKYNGIDPESVIKKYGADTARMFILFKAPPEKDL  659
            ++    +   ++    LE    KMSKS  N ++P+ V+ +YGADT R++ +F +P +  +
Sbjct  588  VEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASI  647

Query  660  EWGDTDVEGQFRFLSRIWKLYINCAKNVNIKSNSYPDKEKSLIKSMNIAIKEISNDILNN  719
             W++ ++EG  +FL R+ +L    +K++        ++  +L K  N ++K +++++ + 
Sbjct  648  AWSEEGLEGSRKFLDRVYRLI--TTKEIT------EENSGALDKVYNETVKAVTEQVDQM  699

Query  720  QFNTAISELMKFYNSLSNSINDVNNNLKIDALKTFCILLAPFAPHIAEEIWH-LIGFKKS  778
            +FNTAI++LM F N+ ++     +++L  D  K F  L+APFAPH++EE+W+ L +   S
Sbjct  700  KFNTAIAQLMVFVNAANK-----EDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGES  754

Query  779  VHLEHWPSFNAEALKEDSYELVIQVNGKVREKVNINHDMNEDQIKELTLKRPNILKWTKD  838
            +    WPS++   L E+  E+V+Q++GKV+ K+ +  D++ ++++E++L   ++     +
Sbjct  755  ISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAG  814

Query  839  KEIRKIIIVKGKIMNIVV  856
            K+I K+I V  K++NIV+
Sbjct  815  KDIIKVIAVPNKLVNIVI  832

1455) leuS in NC_021066


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  520 bits (1963),  Expect = 1e-148, Method: Compositional matrix adjust.
 Identities = 351/865 (41%), Positives = 550/865 (64%), Gaps = 46/865 (5%)

Query  5    YRPEEIESKVQLHWDDHRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIA  63
            Y    IE+K Q  W D++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKKLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            EV T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKTMQRNWIGRSEGVEISFNVNEYADK  242
            V RK + QW +KITAYA+ LL+DL+ +D WP+++K MQRNWIG+S G +++F+V++    
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGCTY--LavaaghplaqqaaaNNPELAAFIDECR-NTKVAEAEMATME  299
            +TV+TTRPDT+ G TY  LA   +   A  ++ +   +A +  +   ++ +A +++A  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGVDTGYKAIHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPV  359
            K GV TG  AI+P+ G E+PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L+I PV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  360  ILAADGSEPDLSGQALTEKGTLFNSGEFDGLSYEAGFNAIADKLAAMGVGERKINYRLRD  419
            + +++  E+ ++ ++L  ++ +     +DGL   +++  + + L A GVG+ ++ YRLRD
Sbjct  362  LEGGNVEEAAFTEDGLHINSDF-----LDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMVTLEDGTVMPTPEDQLPVILP--EDVVMDGIT-SPIKADPEWAKT  476
            W  SRQRYWG PIP++  EDGT  + PE +LP++LP   D+   G   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  T-VNGQPALRETDTFDTFMESSWYYARYTCPQYNDGMLDPNAANYWLPVDIYIGGIEHAI  535
            T  +G  + RET+T      SSWYY RY  P+  + + D +  + WLPVDIY+GG EHA+
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDATVER  595
            +HLLY RF HK++ D G+V + EP ++L+ QGM+L+ ++        R+  +++ AT ++
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY--------RDSRGALVAT-DK  587

Query  596  DEKGRIVKAYDPQGRELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMT  655
             EK R    ++ +  E +  + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D +
Sbjct  588  VEK-RDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  656  LEWQESGVEGANRFLKRVWKLVYEHTTQGPVAALDVASLSEDQQALRRDVHKTIAKVTDD  715
            + W E G+EG+ +FL RV +L         +++ +++   E+  AL +  + T+  VT++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRL---------ITTKEIT--EENSGALDKVYNETVKAVTEQ  695

Query  716  IGRRQTFNTAIAAIMELMNKLAKAPQENEQDRALMREALLAVVRMLNPFTPHACFTLWQE  775
            +++ + FNTAIA +M ++N         +++  L  +   + V+++ PF+PH    LWQ 
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  776  LGGEGD-IDNAPWPVADESAMVENTTLVVVQVNGKVRGKITVPVDATEEQVRARAGQEHL  834
            L + G+ I   PWP  DES +VEN   +VVQ++GKV++K+ V+ D + E+++  A  ++ 
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  835  VAKYLDGVTVRKVIYVPGKLLNLVV  859
            V   + G  + KVI VP KL+N+V+
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVI  832

1456) leuS in NC_013159


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  520 bits (1961),  Expect = 2e-148, Method: Compositional matrix adjust.
 Identities = 356/738 (49%), Positives = 498/738 (68%), Gaps = 60/738 (8%)

Query  217  LVYLSEAPVNWAPGLGTVVANEEVTAEGRTERGNFPVFRRNLRQWMMRITAYAdrllddl  276
            L Y +E PVNW   LGT +ANEEV ++G +ERG +PV R+ +RQWM++ITAYA+RLL+DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  277  drldWPEKIKTMQRNWIGRSRGANVRF--RSGEHTIEVFTTRPDTLFGATYMVLAPEHPL  334
            + +DWPE IK MQRNWIG+S GANV F  +  +  + VFTTRPDTLFGATY VLAPEH+L
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  335  VDELVPAEWSEGVDERWTGGAATPGEAVASYRRETSRKSELDRQE-SKEKTGVFTGAYAT  393
            VD +  ++                +EAVA Y+R++S KS+L R + +KEKTGV TG+YA 
Sbjct  268  VDAITTSD---------------QAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAI  312

Query  394  NPVNGKRIPVFIADYVLMGYGTGAIMAVPGEDQRDWDFATKFGLDILRTVQPgedfdgea  453
            NPVNGK +PV IADYVL +YGTGAIMAVP++D+RDW+FA +F LDI+  ++   + +  A
Sbjct  313  NPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEG-GNVEEAA  371

Query  454  fdgdgaHINSANDEIDLNGLNIEDAKNKIIEWLEHKGHGEGTVQYKLRDWLFARQRYWGE  513
            F  DG HINS      L+GL+   A  K++EWLE  G G+  V Y+LRDWLF+RQRYWGE
Sbjct  372  FTEDGLHINSDF----LDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGE  427

Query  514  PFPIVYDSDGMPIALPEDQLPVVLPEVDDYSPKTFdpedadaepepplaRATDWVEVTLD  573
            P+PI+   DG + A+PE +LP+VLP   D  P            E+PLA  TDW+EVT +
Sbjct  428  PIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSG--------TGESPLANVTDWLEVTRE  479

Query  574  LGDGPKKYWRDTNVMPQWAGSCWYQLRYIDPDNDERFVDPVNERYWMGPRPELHGENDPG  633
             G   +   R+TN MPQWAGS WY LRYIDP+N E++ D    + W+             
Sbjct  480  DGVKGR---RETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWL-------------  523

Query  634  GLDLYVGGVEHGVLHLLYSRFWHKVLYDLGYVSSEEPYRRLYNQGYIQAYAYTDSRGVYV  693
             +D+YVGG EH+VLHLLY+RFWHKVLYDLG V++ EP+++L+NQG I + +Y DSRG  V
Sbjct  524  PVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALV  583

Query  694  PAEEVEERDGKFFY--KGEEVKQEYGKMGKSLKNVVTPDEIAENYGADTFRFYEMSMGPL  751
            +++ VE RDG FF    GEE+ Q  +KM+KSLKNVV PD++ E+YGADT+R YEM MGPL
Sbjct  584  ATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPL  643

Query  752  DVSRPWATKDVVGAHRFLQRLWRLVVNENTGELRVADTELSEEDLRQLHRTIAGVREDYA  811
            D S +W+  ++ G+++FL+R+ RL+   +  E   +  +      +  + T+ +V E+  
Sbjct  644  DASIAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALD------KVYNETVKAVTEQVD  697

Query  812  NLRFNTAGAKLIELNNYVTKTYGSAKATPRGLAEPLVLMLAPMCPHIAEELWHRL-GHSE  870
            +++FNTA A+L+    +V  +    K  + + A  +V ++AP  PH++EELW+ L + +E
Sbjct  698  QMKFNTAIAQLM---VFVNAANKEDKLFS-DYAKGFVQLIAPFAPHLGEELWQALTASGE  753

Query  871  SLVHGPFPTVDERYLVDETVEYPIQVNGKVRSRMTVPADADQEELKKAALADEKIVAALE  930
            S+   P P+ DE  LV++ VE  +Q++GKV++++ V+ D  +EEL+  ALA+EK+ A + 
Sbjct  754  SISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIA  813

Query  931  GAEPRKVIVVPGRLVNVV  948
            G +  KVI VP +LVN+V
Sbjct  814  GKDIIKVIAVPNKLVNIV  831


 Score =  130 bits (476),  Expect = 5e-31, Method: Compositional matrix adjust.
 Identities = 70/147 (48%), Positives = 101/147 (69%), Gaps = 10/147 (6%)

Query  21   IERRWQEYWEANGTYHAPNPVGSLADKDSEVPSDKLFVQDMFPYPSGAGLHVGHPLGFIG  80
            IE +WQ +W  N T+ +          +++ +  K++  DMFPYPSGAGLHVGHP G+ +
Sbjct  9    IEPKWQAFWADNHTFKT----------GTDASKPKFYALDMFPYPSGAGLHVGHPEGYTA  58

Query  81   TDVFARYNRMIGRNVLHTMGFDAFGLPAEQYAVQTGTHPRTTTEANIKRYLAQIRRLGLG  140
            TD+++R++R  G+NVLH MG DAFGLPAEQYA++TG +P   T  NI  +  QI  LG++
Sbjct  59   TDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFS  118

Query  141  HDERRRIATTDVDYYRWTQWIFLQIFN  167
             D  R + TTD +YY+WTQWIF ++++
Sbjct  119  YDWDREVNTTDPNYYKWTQWIFTKLYE  145

1457) leuS in NC_009512


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  520 bits (1962),  Expect = 2e-148, Method: Compositional matrix adjust.
 Identities = 361/884 (41%), Positives = 550/884 (63%), Gaps = 74/884 (8%)

Query  43   YTPRDIEAAAQKFWDEQQSFAVTEQPGKDTYYCLSMFPYPSGK-LHMGHVRNYTIGDVIA  101
            Y    IE+  Q FW ++++F    +++K  +Y L MFPYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  102  RYQRMLGKNVLQPMGWDAFGMPAENAAMKNNVAPAKWTYENIDYMKTQLKSLGLAIDWAR  161
            R++R  G NVL+PMGWDAFG+PAE+ AM     PA  T ENI   K Q+++LG++ DW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  162  EVTTCKPDYYRWEQWLFTRLFEKGIIYRKNGTVNWDPADQTVLANEQVI-DGRGWRSGAL  220
            EV T  P+YY+W QW+FT+L+EKG+ Y  +  VNW     T +ANE+V+ DG + R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  221  IEKREIPMYYFRITDYADELLESLDELPGWPEQVKTMQRNWIGKSRGMEVQFPYDQASIG  280
            + ++ +    ++IT YA+ LLE L+E+ +WPE +K MQRNWIGKS G +V F   ++   
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDT---  239

Query  281  HEGTLKVFTTRPDTLMGATYVAVAAEHPLATQAAQGNPALQAFIDECKSGSVAEADMA--  338
             +  + VFTTRPDTL GATY  +A+EH+L    + ++ A    + + K  +   +D+A  
Sbjct  240  -DKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQA--EAVADYKRQASLKSDLART  296

Query  339  --TQEKKGMATSLLVEHPLTGEKLPVWVANYVLMHYGDGAVMAVPAHDERDFEFAHKYNL  396
              ++EK G+ T+    +P+ G  +PVW+A+YVL  YG GA+MAVPAHDERD EFA ++NL
Sbjct  297  DLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNL  356

Query  397  PVKAVVRTSAGDEVGSEWQAAYGEHGQLINSAEFDGLDFAGAFDAIEAALIRKELGKSRT  456
             + +V+  +  +E      AA+ E+G  INS  +DGLD A+A+  +   L    +G+   
Sbjct  357  DIIPVLEGGNVEE------AAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENV  410

Query  457  QFRLRDWGISRQRYWGCPIPIIHCPSCGDVPVPEDQLPVTLP--ENVVPDGAG-SPLARM  513
             +RLRDW +SRQRYWG PIPIIH       +VPE +LP+ LP   ++ P G+G SPLA +
Sbjct  411  TYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANV  470

Query  514  PEFYECSCPKCGAAAKRETDTMDTFVESSWYFARYASPNYDKGLVDPKAANHWLPVDQYI  573
             +  E +    G  ++RET+TM     SSWY+ RY  P+    L D    ++WLPVD Y+
Sbjct  471  TDWLEVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYV  529

Query  574  GGIEHAILHLLYARFFHKLMRDEGLVTSNEPFKNLLTQGMVVAETYYRVASNGGKDWFNP  633
            GG EHA+LHLLYARF HK++ D G+V ++EPF++L+ QGM+++ +Y              
Sbjct  530  GGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY--------------  575

Query  634  ADVEIERDAKAKIIGARL--KTDG--LPVEIG-----GTEKMSKSKNNGVDPQSMIEAYG  684
                  RD+++ ++++    K DG  + VE G     +  KMSKS +N V+P+ ++E YG
Sbjct  576  ------RDSRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYG  629

Query  685  ADTCRLFMMFASPPDMSLEWSDSGVEGASRFLRRVWRLAQA-HVSQGLPGKLDVAALDDA  743
            ADT R++ MF +P D S+ WS+ G+EG+ +FL RV RL  + ++++  +G LD       
Sbjct  630  ADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALD-------  682

Query  744  QKVIRRAIHAAIKQASTDVGQFHKFNTAIAQVMTVMNVLEKAPQATEQDRALLQEGLEAV  803
                 +  + ++K  + +V+Q  KFNTAIAQ+M  +N       A++++  L+ +   + 
Sbjct  683  -----KVYNETVKAVTEQVDQM-KFNTAIAQLMVFVN-------AANKEDKLFSDYAKGF  729

Query  804  TLLLAPITPHISHALWQHLGHAGSVID-AAWPSVDEQALVQDSITLVVQVNGKLRGQVEM  862
              L+AP++PH+++ LWQ L  +G  I   +WPS DE  LV++ + +VVQ++GK+++++ +
Sbjct  730  VQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVV  789

Query  863  PaaasreeveaaarsnenvLRFIDGLTIRKVIVVPGKLVNIVAN  906
            +   SREE++  A +NE+V   I G  I KVI VP KLVNIV +
Sbjct  790  AKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

1458) leuS in NC_015735


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  519 bits (1958),  Expect = 3e-148, Method: Compositional matrix adjust.
 Identities = 354/866 (41%), Positives = 543/866 (63%), Gaps = 45/866 (5%)

Query  8    LYCPEDIEPTVQQYWHENDTFTVKADPSKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVI  66
            +Y    IEP  Q +W +N+TF   +D+SK K+Y L M+PYPSG  LH+GH   YT  D++
Sbjct  3    FYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDIL  62

Query  67   ARYQRMLGKNVLQPIGWDAFGLPAEGGAVKNNTAPALWTYTNITYMKRQLKLLGFGYDWH  126
            +R++R  G NVL+P+GWDAFGLPAE  A+     PA  T  NI+  KRQ++ LGF+YDW+
Sbjct  63   SRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWD  122

Query  127  REITTCSPEYYRWEQWFFIRLYEKGLVYKKHSSVNWCPQDQTVLANEQVL-NGCCWRCDT  185
            RE+ T  P+YY+W QW+F +LYEKGL Y  + +VNW  +  T +ANE+VL +G   R + 
Sbjct  123  REVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGY  182

Query  186  KVERKEIPQWFVKITAYADELLYDLEKLENWPEQVKTMQRNWIGRSEGVEVTFQVDNSEE  245
             V RK + QW +KITAYA+ LL DLE ++ WPE +K MQRNWIG+S G +VTF+V +++ 
Sbjct  183  PVVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDK  241

Query  246  TLTVYTTRPDTLMGVTYVAVAAGHPLSLQAAVSNTALA---YFIQECRTGKVAEADRAKI  302
             +TV+TTRPDTL G TY  +A+ H+L    + S+ A A   Y  Q    + +A +D AK 
Sbjct  242  DFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK-  300

Query  303  EKKGIATGLHALHPLTGEKLPVWIANFVLMDYGTGAVIAVPGHSQQDFEFASKYNLPIKP  362
            EK G+ TG  A++P+ G  +PVWIA++VL  YGTGA++AVP+H ++D EFA ++NL I P
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  363  VIRNIDGSEPDISTKAMTKKGVLFNSGEFDGLDFQDGFNAIADVLVARGVGKRKINYRLR  422
            V+        ++   A T  G+ +NS+ +DGLD   ++  + + L A GVG+ ++ YRLR
Sbjct  361  VL-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  423  DWGVSRQRYWGAPIPMITLADGTIVPTPAEQLPVVLP--EDLVMNGISSPLKSAQQDWAK  480
            DW  SRQRYWG PIP+I   DGT  + P  +LP+VLP   D+  +G + +  +   DW  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  481  IN-YCGQPALRETDTFDTFMESSWYYARYTCPDYDGGMLDPGAANYWLPVDQYIGGIEHS  539
            +    G  + RET+T      SSWYY RY  P+    + D    + WLPVD Y+GG EH+
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  540  IMHLIYFRFYHKLMRDTGLVNSDEPAKRLLCQGMVLADAFYYLGDSGERVWVSPVEVRVE  599
            ++HL+Y RF HK++ D G+V + EP ++L+ QGM+L+ +  Y +  G  V       +VE
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS--YRDSRGALV----ATDKVE  589

Query  600  RDEQGRIFKATDTTGRVLVYAGMSKMSKSKNNGVDPQEIVNKYGADTVRLFMMFAAPADM  659
            + + G +F     TG  L   + +KMSKS +N V+P+++V++YGADT+R++ MF +P D 
Sbjct  590  KRD-GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  660  TLEWQEAGVEGVNRFLKRVWKLVYEHTQMGQVGTLDITVLNNAQTKLRREVHKTIAKVTL  719
            ++ W E G+EG  +FL RV +L         + T +IT  ++    L +  + T+  VT 
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRL---------ITTKEIT--EENSGALDKVYNETVKAVTE  694

Query  720  DLGCRQMFNTAIVAIMELLNKLTRAPQQTGQDRALLQEALLAVVIMLYPFTPHVCFMLWR  779
            +++ +  FNTAI  +M ++N        + ++  L+ +   + V ++ PF+PH+   LW+
Sbjct  695  QVD-QMKFNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  780  ALGGEGE-IDNAPWLIADESALMEETKMVVIQVNGKLRGKITVPAEADEALVRELALREQ  838
            AL + GE I   PW   DES L+E+   +V+Q++GK+++K+ V+ +     ++E+AL ++
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  839  NVAKYLESNTVRKVIYVSGKLLNLVV  864
            +V   + ++ + KVI V+ KL+N+V+
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVI  832

1459) leuS in NC_013508


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  519 bits (1958),  Expect = 3e-148, Method: Compositional matrix adjust.
 Identities = 354/866 (41%), Positives = 551/866 (64%), Gaps = 48/866 (5%)

Query  5    YRPEDIESHVQRHWDEQKTFQVTEDDSKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIS  63
            Y    IE+  Q  W ++ TF+   D SK K+Y L M+PYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYANIDYMKNQLKLLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T  NI   K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EIATCKPDYYRWEQWFFTKLYEKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDSK  182
            E+ T  P+YY+W QW+FTKLYEKGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITDYADQLLNDLDKLEDWPEQVKTMQRNWIGRSEGVEITFRVADRDDT  242
            V RK + QW +KIT YA++LL+DL+ + DWPE +K MQRNWIG+S G ++TF+V D D  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  FAVYTTRPDTFMGVSYlaiaaahplaqqaaannpalaqFIDECKNTKVAEADMA----TM  298
            F+V+TTRPDT+ G +Y  +A+ H+L +  ++++ A A  + + K      +D+A    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEA--VADYKRQASLKSDLARTDLAK  300

Query  299  EKKGMATGLYAIHPLSGERLPIWVANFVLMDYGTGAVMSVPAHDQRDWEFAAKYHLPMKP  358
            EK G+ TG YAI+P++G  +P+W+A++VL  YGTGA+M+VPAHD+RDWEFA +++L + P
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VILAADGQAPDISAAAMTDKGVLFNSGEFDGLDFSAAFDAVANRLIAAGVGERKVNYRLR  418
            V+     ++ ++  AA T+ G+ +NS+ +DGLD ++A+  + ++L A GVG+ +V YRLR
Sbjct  361  VL-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  419  DWGVSRQRYWGAPIPMVTLEDGSVIPTPEDQLPVILP--EDVVMNGIT-SPLKADPAWAK  475
            DW  SRQRYWG PIP++  EDG+  + PE +LP++LP   D+  +G   SPL     W  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  476  TT-VNGQPALRETDTFDTFMESSWYYARYTCPQYDQGMLDPQAANYWLPVDQYVGGIEHA  534
             T  +G  + RET+T      SSWYY RY  P+  + + D +  + WLPVD YVGG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  535  IMHLMYFRFFHKLMRDAGLVDSDEPAKRLLCQGMVLADAFYYTGANGERNWVSPVDVIVE  594
            ++HL+Y RF HK++ D G+V + EP ++L+ QGM+L+ +  Y ++ G    + + D +  
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS--YRDSRGA---LVATDKVEK  590

Query  595  RDDKGRITKATDRDGRELVYAGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPAEM  654
            RD  G +      +  E    + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P + 
Sbjct  591  RD--GSFFHVETGEELE---QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  655  TLEWQESGVEGANRFLKRVWKLAFDHQQKGPTVALDLTALNDDQKALRRDLHKTIAKVSD  714
            ++ W E G+EG+ +FL RV +L           + ++T  +++  AL +  + T+  V++
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRL---------ITTKEIT--EENSGALDKVYNETVKAVTE  694

Query  715  DIGRRQTFNTAIAAVMELMNKLTRAPQESEQDRALMQEALLAVVRMLYPFTPHVCFTLWS  774
            ++++ + FNTAIA +M ++N        ++++  L  +   + V+++ PF+PH+   LW 
Sbjct  695  QVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  775  ALGGVGdidvapw-pvaddaaMVEDSKLIVVQVNGKVRGKITVAADASEEQVRALAAQEP  833
            AL + G+       P  D++ +VE+   IVVQ++GKV++K+ VA D S E+++ +A  + 
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  834  LVAKYLDGVTVRKVIFVPGKLLNLVV  859
             V   + G  + KVI VP KL+N+V+
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVI  832

1460) ETAF_2377 in NC_017309


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  519 bits (1958),  Expect = 3e-148, Method: Compositional matrix adjust.
 Identities = 354/866 (41%), Positives = 551/866 (64%), Gaps = 48/866 (5%)

Query  5    YRPEDIESHVQRHWDEQKTFQVTEDDSKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIS  63
            Y    IE+  Q  W ++ TF+   D SK K+Y L M+PYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYANIDYMKNQLKLLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T  NI   K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EIATCKPDYYRWEQWFFTKLYEKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDSK  182
            E+ T  P+YY+W QW+FTKLYEKGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITDYADQLLNDLDKLEDWPEQVKTMQRNWIGRSEGVEITFRVADRDDT  242
            V RK + QW +KIT YA++LL+DL+ + DWPE +K MQRNWIG+S G ++TF+V D D  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  FAVYTTRPDTFMGVSYlaiaaahplaqqaaannpalaqFIDECKNTKVAEADMA----TM  298
            F+V+TTRPDT+ G +Y  +A+ H+L +  ++++ A A  + + K      +D+A    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEA--VADYKRQASLKSDLARTDLAK  300

Query  299  EKKGMATGLYAIHPLSGERLPIWVANFVLMDYGTGAVMSVPAHDQRDWEFAAKYHLPMKP  358
            EK G+ TG YAI+P++G  +P+W+A++VL  YGTGA+M+VPAHD+RDWEFA +++L + P
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VILAADGQAPDISAAAMTDKGVLFNSGEFDGLDFSAAFDAVANRLIAAGVGERKVNYRLR  418
            V+     ++ ++  AA T+ G+ +NS+ +DGLD ++A+  + ++L A GVG+ +V YRLR
Sbjct  361  VL-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  419  DWGVSRQRYWGAPIPMVTLEDGSVIPTPEDQLPVILP--EDVVMNGIT-SPLKADPAWAK  475
            DW  SRQRYWG PIP++  EDG+  + PE +LP++LP   D+  +G   SPL     W  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  476  TT-VNGQPALRETDTFDTFMESSWYYARYTCPQYDQGMLDPQAANYWLPVDQYVGGIEHA  534
             T  +G  + RET+T      SSWYY RY  P+  + + D +  + WLPVD YVGG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  535  IMHLMYFRFFHKLMRDAGLVDSDEPAKRLLCQGMVLADAFYYTGANGERNWVSPVDVIVE  594
            ++HL+Y RF HK++ D G+V + EP ++L+ QGM+L+ +  Y ++ G    + + D +  
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS--YRDSRGA---LVATDKVEK  590

Query  595  RDDKGRITKATDRDGRELVYAGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPAEM  654
            RD  G +      +  E    + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P + 
Sbjct  591  RD--GSFFHVETGEELE---QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  655  TLEWQESGVEGANRFLKRVWKLAFDHQQKGPTVALDLTALNDDQKALRRDLHKTIAKVSD  714
            ++ W E G+EG+ +FL RV +L           + ++T  +++  AL +  + T+  V++
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRL---------ITTKEIT--EENSGALDKVYNETVKAVTE  694

Query  715  DIGRRQTFNTAIAAVMELMNKLTRAPQESEQDRALMQEALLAVVRMLYPFTPHVCFTLWS  774
            ++++ + FNTAIA +M ++N        ++++  L  +   + V+++ PF+PH+   LW 
Sbjct  695  QVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  775  ALGGVGdidvapw-pvaddaaMVEDSKLIVVQVNGKVRGKITVAADASEEQVRALAAQEP  833
            AL + G+       P  D++ +VE+   IVVQ++GKV++K+ VA D S E+++ +A  + 
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  834  LVAKYLDGVTVRKVIFVPGKLLNLVV  859
             V   + G  + KVI VP KL+N+V+
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVI  832

1461) Theos_1861 in NC_019386


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  519 bits (1957),  Expect = 4e-148, Method: Compositional matrix adjust.
 Identities = 378/881 (43%), Positives = 553/881 (63%), Gaps = 61/881 (6%)

Query  4    YNPHAIEPKWQRFWKEK-GFMKAREEGKKQ-YVLVMFPYPSG-DLHMGHLKNYTMGDVLA  60
            Y+  AIEPKWQ FW ++  F  + + +K + Y L MFPYPSG +LH+GH   YT  D+L+
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  61   RFRRVQGFQVLHPMGWDAFGLPAENAALKFGLHPRDWTYQNIRQAKESLELMGILYDWDR  120
            RF+R QG +VLHPMGWDAFGLPAE+ A+  G +P + T +NI + K  ++ +G+ YDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  121  EVTTCEPDYYRWNQWLFIKMWEKGLAYRAKGLVNWCPKCQTVLANEQVVEGRCWRHQDTP  180
            EV T +P+YY+W QW+F K+ EKGLAY A   VNW     T +ANE+V+ +    + + P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  181  VEKRELEQWYLRITAYAERLLKDLEGLDWPEKVKAMQRAWIGRSEGAEIRFPIEGREEAI  240
            V ++ + QW L+ITAYAERLL DLE +DWPE +K MQR WIG+S GA++ F + + +  +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  241  TVFTTRPDTLFGATFMVLAPEHPLTLELAAPERKAEVQAYVEAAKRKTEIERQAEGREKT  300
            TVFTTRPDTLFGAT+ VLAPEH+L   ++++++   V  Y   A  K+++ R   ++EKT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  301  GVFLGAYALNPATGERIPIWTADYVLYGYGTGAIMAVPAHDGRDFEFAKRFGLPIRKVIE  360
            GV  G+YA+NP  G  +P+W ADYVL +YGTGAIMAVPAHD RD EFAK+F L I  V+E
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  361  RPGDplpepleaayeepGVMVNSGPFDGTPSEEGKRRVIAWLEEKGLGRARVTYRLRDWL  420
                      EAA+ E G+ +NS+ +DG     +  +++ WLE  G+G   VTYRLRDWL
Sbjct  364  GGN-----VEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWL  418

Query  421  ISRQRYWGTPIPMVHCPACGvvpvpeeelpvllpdlkdvedIRPKGKSPLEAHPEFYETS  480
            +SRQRYWG PIP++H    G      E    L+  +         G SPL    +  E +
Sbjct  419  FSRQRYWGEPIPIIHWED-GTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT  477

Query  481  CPKCGGPARRdtdtmdtffdSSWYYLRYTDPKN-DRLPFDPEKADFWMPVDQYIGGVEHA  539
                G  +RR+T+TM    +SSWYYLRY DP N ++L+ D E    W+PVD Y+GG EHA
Sbjct  478  RED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLA-DEELLKQWLPVDIYVGGAEHA  535

Query  540  VLHLLYSRFFTKFLHDLGMVKVEEPFQGLFTQGMVMAWTDFGEVRVEGDRVLLPEPTRIL  599
            VLHLLY+RF  K L DLG+V   EPFQ LF QGM+++ T + + R       L    ++ 
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILG-TSYRDSRGA-----LVATDKV-  588

Query  600  LETPERELSLEEVKKMGAELRPHPDGTLHLWKPAVMSKSKGNGVMVGPFVKEEGADIARI  659
                         K+ G+ ++ + +  L+   PA MSKS  N V  +  V + GAD  R+
Sbjct  589  ------------EKRDGSFFHVETGEELEQ-APAKMSKSLKNVVNPDDVVEQYGADTLRV  635

Query  660  TILFAAPPENEMVWTEEGVQGAWRFLNRVWRRVAEDREALAAISGVFQAEALEGAERALY  719
              +F +P +  + W+EEG++G+++FL+RV R ++  +E     SG ++          +Y
Sbjct  636  YEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLIT-TKEITEENSGALD---------KVY  685

Query  720  AKLHRTLKKVTDDLEALRFNTAIAALMEFLNALYEYRRENPVTPVYRTAVRYYLQMLFPF  779
               + T+K VT++++ ++FNTAIA LM F+NA     +E+ + + Y  +   ++Q++ PF
Sbjct  686  ---NETVKAVTEQVDQMKFNTAIAQLMVFVNAA---NKEDKLFSDYAKG---FVQLIAPF  736

Query  780  APHIAEEIWHWF--WPDSLFEAGWPeldekaleeeavevavQVNGKVRGTIRIPKDAP--  835
            APH++EE+W+ +    +S+    WP  DE  L E+ VE+ VQ++GKV++ + ++KD +  
Sbjct  737  APHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSRE  796

Query  836  --LEVALAEAKKVRNVQAHLEGKEIVKEIYVPGRILNLVVR  874
               EVALA+ K    VQA++ GK+I+K I VP +++N+V++
Sbjct  797  ELQEVALANEK----VQAEIAGKDIIKVIAVPNKLVNIVIK  833

1462) leuS in NC_021057


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  519 bits (1957),  Expect = 4e-148, Method: Compositional matrix adjust.
 Identities = 354/866 (41%), Positives = 543/866 (63%), Gaps = 45/866 (5%)

Query  4    LYCPEDIEPTVQQYWHENDTFTVKADPSKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVI  62
            +Y    IEP  Q +W +N+TF   +D+SK K+Y L M+PYPSG  LH+GH   YT  D++
Sbjct  3    FYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDIL  62

Query  63   ARYQRMLGKNVLQPIGWDAFGLPAEGGAVKNNTAPALWTYTNITYMKRQLKLLGFGYDWH  122
            +R++R  G NVL+P+GWDAFGLPAE  A+     PA  T  NI+  KRQ++ LGF+YDW+
Sbjct  63   SRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWD  122

Query  123  REITTCSPEYYRWEQWFFIRLYEKGLVYKKHSSVNWCPQDQTVLANEQVL-NGCCWRCDT  181
            RE+ T  P+YY+W QW+F +LYEKGL Y  + +VNW  +  T +ANE+VL +G   R + 
Sbjct  123  REVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGY  182

Query  182  KVERKEIPQWFVKITAYADELLYDLEKLENWPEQVKTMQRNWIGRSEGVEVTFQVDNSEE  241
             V RK + QW +KITAYA+ LL DLE ++ WPE +K MQRNWIG+S G +VTF+V +++ 
Sbjct  183  PVVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDK  241

Query  242  TLTVYTTRPDTLMGVTYVAVAAGHPLSLQAAVSNTALA---YFIQECRTGKVAEADRAKI  298
             +TV+TTRPDTL G TY  +A+ H+L    + S+ A A   Y  Q    + +A +D AK 
Sbjct  242  DFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK-  300

Query  299  EKKGIATGLHALHPLTGEKLPVWIANFVLMDYGTGAVIAVPGHSQQDFEFASKYNLPIKP  358
            EK G+ TG  A++P+ G  +PVWIA++VL  YGTGA++AVP+H ++D EFA ++NL I P
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VIRNIDGSEPDISTKAMTKKGVLFNSGEFDGLDFQDGFNAIADVLVARGVGKRKINYRLR  418
            V+        ++   A T  G+ +NS+ +DGLD   ++  + + L A GVG+ ++ YRLR
Sbjct  361  VL-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  419  DWGVSRQRYWGAPIPMITLADGTIVPTPAEQLPVVLP--EDLVMNGISSPLKSAQQDWAK  476
            DW  SRQRYWG PIP+I   DGT  + P  +LP+VLP   D+  +G + +  +   DW  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  477  IN-YCGQPALRETDTFDTFMESSWYYARYTCPDYDGGMLDPGAANYWLPVDQYIGGIEHS  535
            +    G  + RET+T      SSWYY RY  P+    + D    + WLPVD Y+GG EH+
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  536  IMHLIYFRFYHKLMRDTGLVNSDEPAKRLLCQGMVLADAFYYLGDSGERVWVSPVEVRVE  595
            ++HL+Y RF HK++ D G+V + EP ++L+ QGM+L+ +  Y +  G  V       +VE
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS--YRDSRGALV----ATDKVE  589

Query  596  RDEQGRIFKATDTTGRVLVYAGMSKMSKSKNNGVDPQEIVNKYGADTVRLFMMFAAPADM  655
            + + G +F     TG  L   + +KMSKS +N V+P+++V++YGADT+R++ MF +P D 
Sbjct  590  KRD-GSFFHV--ETGEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  656  TLEWQEAGVEGVNRFLKRVWKLVYEHTQMGQVGTLDITVLNNAQTKLRREVHKTIAKVTL  715
            ++ W E G+EG  +FL RV +L         + T +IT  ++    L +  + T+  VT 
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRL---------ITTKEIT--EENSGALDKVYNETVKAVTE  694

Query  716  DLGCRQMFNTAIVAIMELLNKLTRAPQQTGQDRALLQEALLAVVIMLYPFTPHVCFMLWR  775
            +++ +  FNTAI  +M ++N        + ++  L+ +   + V ++ PF+PH+   LW+
Sbjct  695  QVD-QMKFNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  776  ALGGEGE-IDNAPWLIADESALMEETKMVVIQVNGKLRGKITVPAEADEALVRELALREQ  834
            AL + GE I   PW   DES L+E+   +V+Q++GK+++K+ V+ +     ++E+AL ++
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  835  NVAKYLESNTVRKVIYVSGKLLNLVV  860
            +V   + ++ + KVI V+ KL+N+V+
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVI  832

1463) leuS in NC_017030


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  519 bits (1957),  Expect = 4e-148, Method: Compositional matrix adjust.
 Identities = 347/862 (41%), Positives = 541/862 (63%), Gaps = 69/862 (8%)

Query  7    YEPQSIEGKWQTRWEQEGLFRAGRRPDAPKKYVLEMLPYPSGQ-MHMGHVRNYLIGDVYA  65
            Y+  +IE KWQ+ W ++  F++G  +  PK Y L+M+PYPSG  +H+GH   Y   D+ +
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  66   RYYQMRGFDVLHPMGWDAFGLPAENAAIKDGVHPAIRTRENIESFKAEIKTLGYSYDWTR  125
            R+ + +G +VLHPMGWDAFGLPAE+ A+  G +PA  T ENI +FK +I++LG+SYDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  126  EVNTSQPEYYRWNQWFFLQMLERGLVYRRFSKVNWCTGCHTVIANEQV-KDGRCERCDSE  184
            EVNT++P+YY+W QW+F ++ E+GL Y     VNW     T IANE+V  DG  ER +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  185  VQDKEMPEWAFRITKYSQDLLDALDTLKEWPDRITSAQRNWIGRSDGAEVDFRVQGHDAA  244
            V  K M +W ++IT Y++ LL+ L+ + +WP+ I   QRNWIG+S GA+V F+V++ D  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  245  LRVFTTRVDTLYGCTYVVLAPDHKLVAQVTTADRRADVDAFAKKMAAQNKTERLGEDAEK  304
            + VFTTR DTL+G TY VLAP+H LV  +TT+D+   V  + ++ + ++   R +   EK
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEK  302

Query  305  EGVFTGGYALNPVTGQPVPIWIANFVVSDYGTGAVMSVPAHDARDFVFARKYSLPVRVVI  364
             GV TG+YA+NPV G+ +P+WIA++V++ YGTGA+M+VPAHD RD  FA++++L +  V 
Sbjct  303  TGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV-  361

Query  365  QPASGDKLGAGETLDAAYTEDGVLVDSGDFTGMASAEARVKLAAKLEAQGQGKATVTYRQ  424
                   L +G+  +AA+TEDG+ ++S+ + G+  A A  K+   LEA+G G+  VTYR 
Sbjct  362  -------LEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRL  414

Query  425  KDWGFSRQRYWGTPIPIVYCEKCDPERKGIPVPADQLPVRLPDIDTQAVLTGKGEPPLAK  484
            +DW FSRQRYWG PIPI+  E    +  + +VP  +LP+ LP +  +   +G GE+PLA+
Sbjct  415  RDWLFSRQRYWGEPIPIIHWE----DGTSTAVPESELPLVLP-VTKDIRPSGTGESPLAN  469

Query  485  VPEFVNATCPKCGGPARRETETMDTFVDSCWYFARYLSPKYDVAPFDPKEGKRWLPVDIY  544
            V + ++ T    G  +RRET+TM    +S WY+ RY+ P       D    K+WLPVDIY
Sbjct  470  VTDWLEVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIY  528

Query  545  VGGPEHGVMHLLYFRFWTRVMKLLGLSPVDEPVTRLITQGIVNGA---DGR---------  592
            VGG+EH+V+HLLY RFW +V+  LG+ P  EP  +L+ QG++ G+   D+R         
Sbjct  529  VGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKV  588

Query  593  ---------------------KMGKRYGNGVAPNTIVAKYGADTARTYVLFAGPPERDFD  631
                                 KM+K   N V P+ +V +YGADT R Y +F GP +  + 
Sbjct  589  EKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIA  648

Query  632  WSHEQVEGVFRFLKRVWTLaathhassaeatYSGPYEGKALETRRAAHKCVKRVTEAIER  691
            WS+E +EG  +FL RV  L +T + +          ++ AL+  +  +  VK VTE +++
Sbjct  649  WSEEGLEGSRKFLDRVYRLITTKEITEE--------NSGALD--KVYNETVKAVTEQVDQ  698

Query  692  LSFNTAVAGVMECVNALYAVGTPETPAEKAAMGEAVRLLARILTPIAPHIADELAEAYGA  751
            + FNTA+A +M  VNA        +  E    ++  + + ++++P+APH+++EL +A  A
Sbjct  699  MKFNTAIAQLMVFVNA--------ANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTA  750

Query  752  KASTVT-EAWPEFDPALVVDDVIPYAVQVNGKLraevrvaadageadvraaaeaddkvka  810
             + +++  +WP +D + +V++ +   VQ++GK++A + VA D +  +++  A A++KV+A
Sbjct  751  SGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQA  810

Query  811  aLEGKTLRKFVFVPKRLVNFVV  832
             + GK + K + VP++LVN+V+
Sbjct  811  EIAGKDIIKVIAVPNKLVNIVI  832

1464) leuS in NC_020796


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  519 bits (1957),  Expect = 4e-148, Method: Compositional matrix adjust.
 Identities = 354/866 (41%), Positives = 551/866 (64%), Gaps = 48/866 (5%)

Query  5    YRPEDIESHVQRHWDEQKTFQVTEDDSKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIS  63
            Y    IE+  Q  W ++ TF+   D SK K+Y L M+PYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYANIDYMKNQLKLLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T  NI   K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EIATCKPDYYRWEQWFFTKLYEKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDSK  182
            E+ T  P+YY+W QW+FTKLYEKGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITDYADQLLNDLDKLEDWPEQVKTMQRNWIGRSEGVEITFRVADRDDT  242
            V RK + QW +KIT YA++LL+DL+ + DWPE +K MQRNWIG+S G ++TF+V D D  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  FAVYTTRPDTFMGVSYlaiaaahplaqqaaannpalaqFIDECKNTKVAEADMA----TM  298
            F+V+TTRPDT+ G +Y  +A+ H+L +  ++++ A A  + + K      +D+A    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEA--VADYKRQASLKSDLARTDLAK  300

Query  299  EKKGMATGLYAIHPLSGERLPIWVANFVLMDYGTGAVMSVPAHDQRDWEFAAKYHLPMKP  358
            EK G+ TG YAI+P++G  +P+W+A++VL  YGTGA+M+VPAHD+RDWEFA +++L + P
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VILAADGQAPDISAAAMTDKGVLFNSGEFDGLDFSAAFDAVANRLIAAGVGERKVNYRLR  418
            V+     ++ ++  AA T+ G+ +NS+ +DGLD ++A+  + ++L A GVG+ +V YRLR
Sbjct  361  VL-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  419  DWGVSRQRYWGAPIPMVTLEDGSVIPTPEDQLPVILP--EDVVMNGIT-SPLKADPAWAK  475
            DW  SRQRYWG PIP++  EDG+  + PE +LP++LP   D+  +G   SPL     W  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  476  TT-VNGQPALRETDTFDTFMESSWYYARYTCPQYDQGMLDPQAANYWLPVDQYVGGIEHA  534
             T  +G  + RET+T      SSWYY RY  P+  + + D +  + WLPVD YVGG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  535  IMHLMYFRFFHKLMRDAGLVDSDEPAKRLLCQGMVLADAFYYTGANGERNWVSPVDVIVE  594
            ++HL+Y RF HK++ D G+V + EP ++L+ QGM+L+ +  Y ++ G    + + D +  
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS--YRDSRGA---LVATDKVEK  590

Query  595  RDDKGRITKATDRDGRELVYAGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPAEM  654
            RD  G +      +  E    + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P + 
Sbjct  591  RD--GSFFHVETGEELE---QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  655  TLEWQESGVEGANRFLKRVWKLAFDHQQKGPTVALDLTALNDDQKALRRDLHKTIAKVSD  714
            ++ W E G+EG+ +FL RV +L           + ++T  +++  AL +  + T+  V++
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRL---------ITTKEIT--EENSGALDKVYNETVKAVTE  694

Query  715  DIGRRQTFNTAIAAVMELMNKLTRAPQESEQDRALMQEALLAVVRMLYPFTPHVCFTLWS  774
            ++++ + FNTAIA +M ++N        ++++  L  +   + V+++ PF+PH+   LW 
Sbjct  695  QVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  775  ALGGVGdidvapw-pvaddaaMVEDSKLIVVQVNGKVRGKITVAADASEEQVRTLAAQEP  833
            AL + G+       P  D++ +VE+   IVVQ++GKV++K+ VA D S E+++ +A  + 
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  834  LVAKYLDGVTVRKVIFVPGKLLNLVV  859
             V   + G  + KVI VP KL+N+V+
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVI  832

1465) YSA_03698 in NC_017986


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  519 bits (1957),  Expect = 4e-148, Method: Compositional matrix adjust.
 Identities = 361/884 (41%), Positives = 550/884 (63%), Gaps = 74/884 (8%)

Query  5    YTPRDIEAAAQKFWDEQQSFAVTEQPGKDTYYCLSMFPYPSGK-LHMGHVRNYTIGDVIA  63
            Y    IE+  Q FW ++++F    +++K  +Y L MFPYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPMGWDAFGMPAENAAMKNNVAPAKWTYENIDYMKTQLKSLGLAIDWAR  123
            R++R  G NVL+PMGWDAFG+PAE+ AM     PA  T ENI   K Q+++LG++ DW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVTTCKPDYYRWEQWLFTRLFEKGIIYRKNGTVNWDPADQTVLANEQVI-DGRGWRSGAL  182
            EV T  P+YY+W QW+FT+L+EKG+ Y  +  VNW     T +ANE+V+ DG + R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  IEKREIPMYYFRITDYADELLESLDELPGWPEQVKTMQRNWIGKSRGMEVQFPYDQASIG  242
            + ++ +    ++IT YA+ LLE L+E+ +WPE +K MQRNWIGKS G +V F   ++   
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDT---  239

Query  243  HEGTLKVFTTRPDTLMGATYVAVAAEHPLATQAAQGNPALQAFIDECKSGSVAEADMA--  300
             +  + VFTTRPDTL GATY  +A+EH+L    + ++ A    + + K  +   +D+A  
Sbjct  240  -DKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQA--EAVADYKRQASLKSDLART  296

Query  301  --TQEKKGMATSLLVEHPLTGEKLPVWVANYVLMHYGDGAVMAVPAHDERDFEFAHKYNL  358
              ++EK G+ T+    +P+ G  +PVW+A+YVL  YG GA+MAVPAHDERD EFA ++NL
Sbjct  297  DLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNL  356

Query  359  PVKAVVRTSAGDEVGSEWQAAYGEHGQLINSAEFDGLDFAGAFDAIEAALIRKELGKSRT  418
             + +V+  +  +E      AA+ E+G  INS  +DGLD A+A+  +   L    +G+   
Sbjct  357  DIIPVLEGGNVEE------AAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENV  410

Query  419  QFRLRDWGISRQRYWGCPIPIIHCPSCGDVPVPEDQLPVTLP--ENVVPDGAG-SPLARM  475
             +RLRDW +SRQRYWG PIPIIH       +VPE +LP+ LP   ++ P G+G SPLA +
Sbjct  411  TYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANV  470

Query  476  PEFYECSCPKCGAAAKRETDTMDTFVESSWYFARYASPNYDKGLVDPKAANHWLPVDQYI  535
             +  E +    G  ++RET+TM     SSWY+ RY  P+    L D    ++WLPVD Y+
Sbjct  471  TDWLEVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYV  529

Query  536  GGIEHAILHLLYARFFHKLMRDEGLVTSNEPFKNLLTQGMVVAETYYRVASNGGKDWFNP  595
            GG EHA+LHLLYARF HK++ D G+V ++EPF++L+ QGM+++ +Y              
Sbjct  530  GGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY--------------  575

Query  596  ADVEIERDAKAKIIGARL--KTDG--LPVEIG-----GTEKMSKSKNNGVDPQSMIEAYG  646
                  RD+++ ++++    K DG  + VE G     +  KMSKS +N V+P+ ++E YG
Sbjct  576  ------RDSRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYG  629

Query  647  ADTCRLFMMFASPPDMSLEWSDSGVEGASRFLRRVWRLAQA-HVSQGLPGKLDVAALDDA  705
            ADT R++ MF +P D S+ WS+ G+EG+ +FL RV RL  + ++++  +G LD       
Sbjct  630  ADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALD-------  682

Query  706  QKVIRRAIHAAIKQASTDVGQFHKFNTAIAQVMTVMNVLEKAPQATEQDRALLQEGLEAV  765
                 +  + ++K  + +V+Q  KFNTAIAQ+M  +N       A++++  L+ +   + 
Sbjct  683  -----KVYNETVKAVTEQVDQM-KFNTAIAQLMVFVN-------AANKEDKLFSDYAKGF  729

Query  766  TLLLAPITPHISHALWQHLGHAGSVID-AAWPSVDEQALVQDSITLVVQVNGKLRGQVEM  824
              L+AP++PH+++ LWQ L  +G  I   +WPS DE  LV++ + +VVQ++GK+++++ +
Sbjct  730  VQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVV  789

Query  825  PaaasreeveaaarsnenvLRFIDGLTIRKVIVVPGKLVNIVAN  868
            +   SREE++  A +NE+V   I G  I KVI VP KLVNIV +
Sbjct  790  AKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

1466) T1E_4712 in NC_018220


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  519 bits (1957),  Expect = 4e-148, Method: Compositional matrix adjust.
 Identities = 361/884 (41%), Positives = 550/884 (63%), Gaps = 74/884 (8%)

Query  5    YTPRDIEAAAQKFWDEQQSFAVTEQPGKDTYYCLSMFPYPSGK-LHMGHVRNYTIGDVIA  63
            Y    IE+  Q FW ++++F    +++K  +Y L MFPYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPMGWDAFGMPAENAAMKNNVAPAKWTYENIDYMKTQLKSLGLAIDWAR  123
            R++R  G NVL+PMGWDAFG+PAE+ AM     PA  T ENI   K Q+++LG++ DW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVTTCKPDYYRWEQWLFTRLFEKGIIYRKNGTVNWDPADQTVLANEQVI-DGRGWRSGAL  182
            EV T  P+YY+W QW+FT+L+EKG+ Y  +  VNW     T +ANE+V+ DG + R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  IEKREIPMYYFRITDYADELLESLDELPGWPEQVKTMQRNWIGKSRGMEVQFPYDQASIG  242
            + ++ +    ++IT YA+ LLE L+E+ +WPE +K MQRNWIGKS G +V F   ++   
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDT---  239

Query  243  HEGTLKVFTTRPDTLMGATYVAVAAEHPLATQAAQGNPALQAFIDECKSGSVAEADMA--  300
             +  + VFTTRPDTL GATY  +A+EH+L    + ++ A    + + K  +   +D+A  
Sbjct  240  -DKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQA--EAVADYKRQASLKSDLART  296

Query  301  --TQEKKGMATSLLVEHPLTGEKLPVWVANYVLMHYGDGAVMAVPAHDERDFEFAHKYNL  358
              ++EK G+ T+    +P+ G  +PVW+A+YVL  YG GA+MAVPAHDERD EFA ++NL
Sbjct  297  DLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNL  356

Query  359  PVKAVVRTSAGDEVGSEWQAAYGEHGQLINSAEFDGLDFAGAFDAIEAALIRKELGKSRT  418
             + +V+  +  +E      AA+ E+G  INS  +DGLD A+A+  +   L    +G+   
Sbjct  357  DIIPVLEGGNVEE------AAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENV  410

Query  419  QFRLRDWGISRQRYWGCPIPIIHCPSCGDVPVPEDQLPVTLP--ENVVPDGAG-SPLARM  475
             +RLRDW +SRQRYWG PIPIIH       +VPE +LP+ LP   ++ P G+G SPLA +
Sbjct  411  TYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANV  470

Query  476  PEFYECSCPKCGAAAKRETDTMDTFVESSWYFARYASPNYDKGLVDPKAANHWLPVDQYI  535
             +  E +    G  ++RET+TM     SSWY+ RY  P+    L D    ++WLPVD Y+
Sbjct  471  TDWLEVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYV  529

Query  536  GGIEHAILHLLYARFFHKLMRDEGLVTSNEPFKNLLTQGMVVAETYYRVASNGGKDWFNP  595
            GG EHA+LHLLYARF HK++ D G+V ++EPF++L+ QGM+++ +Y              
Sbjct  530  GGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY--------------  575

Query  596  ADVEIERDAKAKIIGARL--KTDG--LPVEIG-----GTEKMSKSKNNGVDPQSMIEAYG  646
                  RD+++ ++++    K DG  + VE G     +  KMSKS +N V+P+ ++E YG
Sbjct  576  ------RDSRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYG  629

Query  647  ADTCRLFMMFASPPDMSLEWSDSGVEGASRFLRRVWRLAQA-HVSQGLPGKLDVAALDDA  705
            ADT R++ MF +P D S+ WS+ G+EG+ +FL RV RL  + ++++  +G LD       
Sbjct  630  ADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALD-------  682

Query  706  QKVIRRAIHAAIKQASTDVGQFHKFNTAIAQVMTVMNVLEKAPQATEQDRALLQEGLEAV  765
                 +  + ++K  + +V+Q  KFNTAIAQ+M  +N       A++++  L+ +   + 
Sbjct  683  -----KVYNETVKAVTEQVDQM-KFNTAIAQLMVFVN-------AANKEDKLFSDYAKGF  729

Query  766  TLLLAPITPHISHALWQHLGHAGSVID-AAWPSVDEQALVQDSITLVVQVNGKLRGQVEM  824
              L+AP++PH+++ LWQ L  +G  I   +WPS DE  LV++ + +VVQ++GK+++++ +
Sbjct  730  VQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVV  789

Query  825  PaaasreeveaaarsnenvLRFIDGLTIRKVIVVPGKLVNIVAN  868
            +   SREE++  A +NE+V   I G  I KVI VP KLVNIV +
Sbjct  790  AKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

1467) KTR9_4724 in NC_018581


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  518 bits (1956),  Expect = 5e-148, Method: Compositional matrix adjust.
 Identities = 363/782 (47%), Positives = 506/782 (65%), Gaps = 67/782 (8%)

Query  193  SELVDEFASGARALGVKYEGRDWA-DLSPAERT---------EILDDHRLVYLSDSLVNW  242
            +E + +F     ALG  Y   DW  +++ ++             L +  L Y ++  VNW
Sbjct  102  AENIANFKRQINALGFSY---DWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNW  158

Query  243  CPGLGTVLANEEVTADGRSDRGNFPVFRKHLRQWMMRITAYSdrllddldlldWPDKVKT  302
               LGT +ANEEV +DG S+RG +PV RK +RQWM++ITAY++RLL+DL+ +DWP+ +K 
Sbjct  159  VEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKD  218

Query  303  MQRNWIGRSRGAQVRFDVPGVG-GIEVFTTRPDTLFGATYMVLAPEHPLVDELTAGQWPS  361
            MQRNWIG+S GA+V F V + + ++ VFTTRPDTLFGATY VLAPEH+LVD +T+     
Sbjct  219  MQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHALVDAITT-----  273

Query  362  GTDDRWTRGGADPAAAVAEYRASIAAKSDLERQE-NKEKTGVFTGSFAVNPVNGEQVPVF  420
                      +D A AVA+Y+   + KSDL R +  KEKTGV TGS+A+NPVNG ++PV 
Sbjct  274  ----------SDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAINPVNGKEMPVW  323

Query  421  VADYVLMGYGTGAIMAVPAHDARDHEFATVFGLPIREVIGSDTDIAAEAYVGDGPLVNSG  480
            +ADYVL +YGTGAIMAVPAHD RD EFA  F L I  V+ ++ ++   A+  DG  +NS+
Sbjct  324  IADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGG-NVEEAAFTEDGLHINSD  382

Query  481  FLDGRNVEDAKAAIVERLEADGVGTGRIQYKLRDWLFARQRYWGEPFPIVYDAAGQPHAL  540
            FLDG +   A A +VE+LEA+GVG   + Y+LRDWLF+RQRYWGEP+PI+    G + A+
Sbjct  383  FLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAV  442

Query  541  PESMLPVELPEVDDYAPVsfdpddadsepsppLAKATEWMTVELDLGDGVQTYTRDANVM  600
            PES LP+ LP   D  P         +   +PLA+ T+W+ V  +  DGV+   R++N M
Sbjct  443  PESELPLVLPVTKDIRP--------SGTGESPLANVTDWLEVTRE--DGVKG-RRETNTM  491

Query  601  PQWAGSSWYQLRYIDPTNSETLCAKENEAYWMGPRPALHGANDPGGLDLYIGGVEHAVLH  660
            PQWAGSSWY LRYIDP N+E L   E    W+              +D+Y+GG EHAVLH
Sbjct  492  PQWAGSSWYYLRYIDPHNTEKLADEELLKQWLP-------------VDIYVGGAEHAVLH  538

Query  661  LLYSRFWHKVLFDLGYVTSREPYRKLFNQGMIQAYAYTDSRGIYVPAEEVTEENGEFFY-  719
            LLY+RFWHKVL+DLG V ++EP++KLFNQGMI + +Y DSRG  V+++ V   +G FF  
Sbjct  539  LLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHV  598

Query  720  -NGEKVRQEYGKMGKSLKNSVAPDDICRDYGADTLRVYEMFMGPLDQSRPWATKDVVGSQ  778
              GE + Q  +KM+KSLKN V PDD+  +YGADTLRVYEMFMGPLD S +W+  ++ GS+
Sbjct  599  ETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSR  658

Query  779  RFLQRIWRLVVDEESGALRVADTELDDDTKRLLHKTIAGVREDYDALRNNTAVAKLTVLT  838
            +FL+R+ RL+   E         E  +   ++ + T+ +V E+ D ++ NTA+A+L V+ 
Sbjct  659  KFLDRVYRLITTKEITE------ENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFV  712

Query  839  NHLTKNFEKSGAPRDAVEPLVIMLAPLAPHIAEELWHRLGRDTLVVR-ASFPVADEAWLV  897
            N   K+        D    +V ++AP+APH++EELW+ L      +   + P  DE+ LV
Sbjct  713  NAANKE---DKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLV  769

Query  898  EDTVEIPVQVKGKVRSRITVAADADEDTMRAAALADEKIVAILDGAEPRKVIVVPGRMVN  957
            E+ VEI VQ+KGKV++++ VA D   + ++  ALA+EK+ A + G +  KVI VP ++VN
Sbjct  770  ENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVN  829

Query  958  IV  959
            IV
Sbjct  830  IV  831


 Score =  128 bits (468),  Expect = 2e-30, Method: Compositional matrix adjust.
 Identities = 70/155 (46%), Positives = 101/155 (66%), Gaps = 16/155 (10%)

Query  25   GEIEQRWQQTWSDERAYEAPNPVGPLAGDLSAFGGGDADAAEKLFVQDMFPYPSGAGLHV  84
              IE +WQ  W+D++++ +                G   +  K++  DMFPYPSGAGLHV
Sbjct  7    TAIEPKWQAFWADNHTFKT----------------GTDASKPKFYALDMFPYPSGAGLHV  50

Query  85   GHPLGFIASDVFARYQRMTGKNVLHTMGFDSFGLPAEQYAVQTGTHPRTTTEQNIERYLG  144
            GHP G+ A+D+++R++R  G NVLH MG D+FGLPAEQYA++TG +P   T +NI  +  
Sbjct  51   GHPEGYTATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKR  110

Query  145  QIRRLGLGHDERRRVATTDVDFYRWTQWIFLQIYN  179
            QI  LG++ D  R V TTD ++Y+WTQWIF ++Y+
Sbjct  111  QINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1468) TK90_2132 in NC_013889


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  518 bits (1956),  Expect = 5e-148, Method: Compositional matrix adjust.
 Identities = 359/870 (42%), Positives = 560/870 (65%), Gaps = 53/870 (6%)

Query  5    YSPKEIEAQVQRQWEESDCFRAREDAPGEPFYCLSMFPYPSGK-LHMGHVRNYTIGDVIA  63
            Y    IE++ Q  W +++ F++  DA+   FY L MFPYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RFQRMQGRSVLQPMGWDAFGLPAENAAMQNHVPPAAWTRQNIEQMRTQLKRLGFAYDWSR  123
            RF+R QG++VL+PMGWDAFGLPAE+ AM+    PA  T +NI + + Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EFATCDADYYRWEQWLFVRLLKKGLVYRKKATVNWDPVDQTVLANEQVI-EGRGWRSGAL  182
            E  T D++YY+W QW+F +L  KGL Y     VNW     T +ANE+V+ +G + R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERREMPQWFLRITDYADELLEALDGLNGWPDQVRTMQRNWIGRSEGVELEFAV-DGGEP  241
            V R+ M QW L+IT YA+ LLE L+ ++ WP+ ++ MQRNWIG+S G ++ F V D +  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  242  LTVYTTRPDTLFGVSYMALAPEHPRVQALAENDAELAAFVADCAQGGVAEADLA----TM  297
            +TV+TTRPDTLFG +Y  LAPEH+ V+A++ +D   A  VAD  + +   +DLA    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEA--VADYKRQASLKSDLARTDLAK  300

Query  298  EKKGRPLGFTARHPLTGAEVPVWVANFVLMEYGTGAVMAVPAHDERDHEFATKYDLPIRQ  357
            EK G   G  A +P+ G E+PVW+A++VL  YGTGA+MAVPAHDERD EFA +++L I  
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  358  VIAPADGAECDVQAAAFTEAGVLVNSGDFDGQaseaakaaiaehleqaglgrrrrnyrlr  417
            V+  +     +V+ AAFTE G+ +NS+ +DG    +A A + E LE  G+G     YRLR
Sbjct  361  VLEGG-----NVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  418  DWGISRQRYWGCPIPVIHCDACGAVPVPEEDLPVRLP--EDVIPDGAG-SPLARMPEFFE  474
            DW +SRQRYWG PIP+IH +   + +VPE +LP+ LP   D+ P G+G SPLA + + +E
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  475  ASCPECGKPARRETDTFDTFFESSWYFARYACADNDTAMLDAR-ADHWLPVDQYVGGIEH  533
             +  +  K +RRET+T      SSWY+ RY  ++N   + D     +WLPVD YVGG EH
Sbjct  476  VTREDGVK-GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEH  534

Query  534  AVLHLLYARFFHKLLRDEGLLASDEPFTRLLTQGMVIAPTFYRERDDGGKDWINPADVEL  593
            AVLHLLYARF HK+L D G++++ EPF +L+ QGM+++ + YR+  ++    + ++D  +
Sbjct  535  AVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS-YRDSRGA----LVATD-KV  588

Query  594  ERAEDGSVKAARHREDGLPVMVGGMEKMSKSKNNGVDPQALIERFGADTARLFTMFAAPP  653
            E+ +++        E     +  +  KMSKS +N V+P+ ++E++GADT R++ MF +P 
Sbjct  589  EKRDGSFFHVETGEE-----LEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPL  643

Query  654  DLSLEWSDSGVEGAHRFIKRLWRAV-HEHVNGDAPGALEVDALDDAGRELRRKLHDTIAK  712
            D S+ WS+ G+EG+++F+ R+ R +   ++  + +GAL+            +  ++T+  
Sbjct  644  DASIAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALD------------KVYNETVKA  691

Query  713  VTDDIGRRQTFNTAVAANMELLNDLGKFPKDAPLVAVVRQEALEGIVRMLAPIIPHVTET  772
            VT+++++ + FNTA+A  M ++N      K+  L +    +   G+V+++AP+ PH+ E 
Sbjct  692  VTEQVDQMK-FNTAIAQLMVFVNAAN---KEDKLFS----DYAKGFVQLIAPFAPHLGEE  743

Query  773  LWRAL-GHDELVATTAWPTVDEAARQAAQETLAVQVNGKRRAEIAVPAGADRDAIEATAR  831
            LW+AL + +E ++  +WP+ DE+     +  + VQ++GK +A + V+ +  R+ ++  A 
Sbjct  744  LWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVAL  803

Query  832  GDENVQRHIEGHNVVKVIVVPGRLVNFVVK  861
            ++E+VQ +I G +++KVI VP +LVN+V+K
Sbjct  804  ANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

1469) Metme_3062 in NC_015572


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  518 bits (1955),  Expect = 5e-148, Method: Compositional matrix adjust.
 Identities = 352/876 (41%), Positives = 543/876 (62%), Gaps = 65/876 (7%)

Query  5    YKPLPIEQKVQADWEKSGVFTASENTGKEKYYCLSMFPYPSGK-LHMGHVRNYTIGDVIS  63
            Y   +IE K QA W  +  F ++ +++K K+Y L MFPYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RFQRMQGKHVLQPMGWDAFGLPAENAAMQNKVHPADWTYSNIDYMRDQLKRLGFGYDWSR  123
            RF+R QG +VL+PMGWDAFGLPAE+ AM+   +PA+ T  NI   + Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCDPEYYRWEQWFFLRLMEKGLVYKKTAPVNWCPHDQTVLANEQVI-DGCCWRCDTL  182
            E+ T DP+YY+W QW+F +L EKGL Y    PVNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VEKKEISQWFLKITEYADELLSSLESLPGWPEQVRTMQANWIGRSEGVEMDFAVEGFDEP  242
            V +K + QW LKIT YA+ LL  LE + +WPE ++ MQ NWIG+S G ++ F V + D  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  VRIYTTRPDTVMGVTYVAVAAEHPVAK--KAAEGNADIAAFLESCKQmetseaametmeK  300
              ++TTRPDT+ G TY  +A+EH++     +++    +A +            +  + EK
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEK  302

Query  301  RGIASGFTATHPLTGEQVPVWIANFVLMSYGTGAVMSVPAHDQRDYEFAKRYGIAIKEVI  360
             G+ +G  A +P+ G ++PVWIA++VL SYGTGA+M+VPAHD+RD EFAK++ + I  V+
Sbjct  303  TGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL  362

Query  361  asadgaddsvvdkaFTEKGVLKNSGDFDGLNFTQAFDAIAAKLADLGKGERKTNFRLRDW  420
                  +++V + AFTE G+  NS+ +DGL+ + A+  +   L   G G+ +  +RLRDW
Sbjct  363  -----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDW  417

Query  421  GVSRQRYWGAPVPVIYCDDCGTVPVPDDQLPVTLP--RDVVLDGS-QSPLAAHPTFPHAD  477
              SRQRYWG P+P+I  +D  + +VP+ +LP+ LP  +D+   G+ +SPLA      +  
Sbjct  418  LFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT  477

Query  478  CPKCGKPARRETDTFDTFMESSWYFARY-ASQDCDTAMLDSRADYWLPVDHYIGGIEHAI  536
                 K +RRET+T      SSWY+ RY  +++ +    +     WLPVD Y+GG EHA+
Sbjct  478  REDGVK-GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  537  LHLLYARFYTKLLRDEGLIVCDEPFKNLLTQGMVVAETFYQIDEHGHKRYYNLTQIEVER  596
            LHLLYARF  K+L D G++   EPF++L+ QGM+++ ++                    R
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY--------------------R  576

Query  597  DSKGKIVGAKLL--KDGS--PVTVG-----AIEKMSKSKNNGVDPQVLIDQYGADTVRLY  647
            DS+G +V++  +  +DGS   V  G     A  KMSKS +N V+P+ +++QYGADT+R+Y
Sbjct  577  DSRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVY  636

Query  648  TMFTSPPDQSLEWNDAGVEGAFRFLKRLWRQVYLHVETGLPGKGLEAAALTDGQKALRRQ  707
             MF +P D S+ W++ G+EG+ +FL R+ R +          K +      +   AL + 
Sbjct  637  EMFMGPLDASIAWSEEGLEGSRKFLDRVYRLI--------TTKEITE----ENSGALDKV  684

Query  708  LHQALQKVTDDMARRHTFNTAIAANMELVNALNKFEDDSDNGRAVRQETLEGIVLMLAPI  767
             +++++ VT+++ +   FNTAIA  M +VNA NK          +  +   G+V ++AP+
Sbjct  685  YNETVKAVTEQVDQMK-FNTAIAQLMVFVNAANK-------EDKLFSDYAKGFVQLIAPF  736

Query  768  IPHAAQQLWQELGHTGDIVM-AAWPTLDETALVQDAIEMVVQVNGKLRGKFSVAATESKE  826
             PH +++LWQ L  +G+ +   +WP+ DE+ LV++ +E+VVQ++GK+++K+ VA   S+E
Sbjct  737  APHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSRE  796

Query  827  QIEALVLADEHVQRYIDGKPVKKLIVVPQKLVNIVV  862
            +++ + LA+E VQ  I GK + K+I VP+KLVNIV+
Sbjct  797  ELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

1470) Mycch_5305 in NC_018027


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  518 bits (1954),  Expect = 7e-148, Method: Compositional matrix adjust.
 Identities = 345/732 (48%), Positives = 493/732 (68%), Gaps = 51/732 (6%)

Query  244  LVYLADSVVNWCPGLGTVLANEEVTADGRSERGNFPVFRKRLRQWMMRITAYSDRLLEDL  303
            L Y A+  VNW   LGT +ANEEV +DG SERG +PV RK +RQWM++ITAY++RLLEDL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  304  DALEWPEKVKTMQRNWIGRSTGASVLFGTDAGDVE--VFTTRPDTLFGATYLVLAPEHDL  361
            + ++WPE +K MQRNWIG+STGA+V F     D +  VFTTRPDTLFGATY VLAPEH L
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  362  VDRLVADEWPAEVDSRWTYGAATPRDAVAAYRTAIAAKSDLERQE-NKTKTGVFLGAYAV  420
            VD + + +                 +AVA Y+   + KSDL R +  K KTGV  G+YA+
Sbjct  268  VDAITTSD---------------QAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAI  312

Query  421  NPADGQQVPVFIADYVLAGYGTGAIMAVPGGDQRDWDFATEFGLPIVEVVAGGDISQEAY  480
            NP +G+++PV IADYVLA+YGTGAIMAVP+ D+RDW+FA +F L I+ V+ GG++ + A+
Sbjct  313  NPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEAAF  372

Query  481  TGDGLLVNSGFLDGMDVAAAKEAMTERLTADGRGRARIEYKLRDWLFARQRYWGEPFPIV  540
            T DGL +NS+FLDG+D A+A   M E+L A+G G   + Y+LRDWLF+RQRYWGEP+PI+
Sbjct  373  TEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPII  432

Query  541  YDADGRAHplpdellpvelpdvpdYSPVLFDPNDADSEPSPPLAKVSDWVNVELDLGDGF  600
               DG + ++P+  LP+ LP   D  P         +   +PLA+V+DW++V  +  DG 
Sbjct  433  HWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTDWLEVTRE--DGV  482

Query  601  KSYTRDTNVMPQWAGSSWYELRYTDPHNKEAMCAKENEAYWMGPRPAEHGPNDPGGVDLY  660
            K+  R+TN MPQWAGSSWY LRY DPHN E +   E    W+              VD+Y
Sbjct  483  KG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWL-------------PVDIY  528

Query  661  VGGVEHAVLHLLYSRFWHKVLYDLGHVSSREPYRRLVNQGYIQAFAYTDARGSYVPAAEV  720
            VGG EHAVLHLLY+RFWHKVLYDLG V+++EP+++L NQG I + +Y D+RG+ V++  V
Sbjct  529  VGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKV  588

Query  721  SERDGKFYWAGPDGEIEVNQEFGKIGKSLKNSVSPDEICDNYGADTLRVYEMSMGPLEAS  780
              RDG F+    +   E++Q  +K++KSLKN V+PD++ ++YGADTLRVYEM MGPL+AS
Sbjct  589  EKRDGSFF--HVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  781  RPWATKDVVGAHRFLQRVWRLVVDEECGVPRVTDDPLDDETLRLLHRTIAGTADDYAALR  840
             +W+  ++ G+++FL+RV RL+   E  +     ++LD    ++ + T+ + +++   ++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLITTKE--ITEENSGALD----KVYNETVKAVTEQVDQMK  700

Query  841  NNTAAAKLIEYTNHLTKQGVTARAALEPLVLMVAPLAPHLAEELWMRL-GHEASLAHGPF  899
             NTA A+L+ + N   K++         +V ++AP+APHL+EELW  L +   S++  P 
Sbjct  701  FNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPW  760

Query  900  PVADERYLVEDTVEYPVQVNGKVRGRVTIaadagadtveaaaladEKVLAFLDGRTPKKV  959
            P  DE  LVE+ VE  VQ++GKV++++ +A D + + ++  ALA+EKV A + G+   KV
Sbjct  761  PSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKV  820

Query  960  IVVAGRLVNVVV  971
            I V+ +LVN+V+
Sbjct  821  IAVPNKLVNIVI  832


 Score =  130 bits (475),  Expect = 6e-31, Method: Compositional matrix adjust.
 Identities = 75/150 (50%), Positives = 101/150 (68%), Gaps = 11/150 (7%)

Query  45   GAIERTWQHRWTESGTFNVANPVGSLAPADGSPVPTDKMFVQDMFPYPSGEGLHVGHPLG  104
             AIE  WQ  W+++ TF+            G+  +  K +  DMFPYPSG GLHVGHP G
Sbjct  7    TAIEPKWQAFWADNHTFKT-----------GTDASKPKFYALDMFPYPSGAGLHVGHPEG  55

Query  105  YIATDVYARYYRMTGRNVLHALGFDAFGLPAEQYAIQTGTHPRTRTEANIVNFRRQLGRL  164
            Y ATD+ +R+ R  G+NVLH++G DAFGLPAEQYA++TG +P   T  NI NF+RQ+  L
Sbjct  56   YTATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINAL  115

Query  165  GLGHDTRRSFSTTDVDFYKWTQWIFLQIYN  194
            G++ D  R  +TTD ++YKWTQWIF ++Y+
Sbjct  116  GFSYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1471) leuS in NC_012962


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  518 bits (1954),  Expect = 7e-148, Method: Compositional matrix adjust.
 Identities = 349/866 (41%), Positives = 543/866 (63%), Gaps = 48/866 (5%)

Query  5    YRPEDIEPQVQLHWQEKQTFKVTEDNSKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIS  63
            Y    IEP+ Q  W +++TFK   D SK K+Y L M+PYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYANIEYMKGQLKTLGFGYDWDR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T  NI   K Q+++LGF+YDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVTTCTPEYYRWEQWFFTKLYEKGLVYKKTSAVNWCPHDLTVLANEQVV-DGCCWRCDTK  182
            EV T  P+YY+W QW+FTKLYEKGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYAeellndldtleeWPEQVKTMQRNWIGRSEGIEITFDVADSQEK  242
            V RK + QW +KITAYA E L +     +WPE +K MQRNWIG+S G ++TF V D++  
Sbjct  184  VVRKPMRQWMLKITAYA-ERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFLGATYVAVAAGHPLAKQAVEINPELVAFIDECRNTKVAEADMA----TM  298
            +TV+TTRPDT++GATY  +A+ H+L        ++    + + +      +D+A    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAIT--TSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  299  EKKGMATGMFAIHPLTKEKVAIWVANFVLMEYGTGAVMAVPGHDQRDWEFATKYNLPMKA  358
            EK G+ TG +AI+P+    +++W+A++VL  YGTGA+MAVP+HD+RDWEFA ++NL + +
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VILDNEGNEPNVHEAPVTDKNVLFNSGEFNGLNHEAGFNAIADKLVEMGVGKRKVNYRLR  418
            V+     +  NV+EA+ T+  + +NS+ ++GL+  +++  + + L   GVG+ +V YRLR
Sbjct  361  VL-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  419  DWGVSRQRYWGAPIPMATLEDGTVVPVPADQLPVILP--EDVKMDGIT-SPIKADPEWAK  475
            DW  SRQRYWG PIP+   EDGT  +VP  +LP++LP   D++  G   SP+    +W  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  476  TT-INGQPALRETDTFDTFMESSWYYARYTCPDYDKGLLDPAAANYWLPVDQYIGGIEHA  534
             T  +G  + RET+T      SSWYY RY  P+    L D    + WLPVD Y+GG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  535  IMHLMYFRFFHKLMRDAGMVNSNEPAKRLLCQGMVLADAFYYIGKNGEKIWVSPADTHVE  594
            ++HL+Y RF HK++ D G+V ++EP ++L+ QGM+L+ +  Y +  G  +    A   VE
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS--YRDSRGALV----ATDKVE  589

Query  595  RDDKGRIIKATDKEGHELVYTGMSKMSKSKNNGIDPQLMVEKYGADTVRLFMMFAAPPEL  654
            + D G ++     E  E    + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P + 
Sbjct  590  KRD-GSFFHVETGEELE---QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  655  TLEWQESSVEGANRFLKRVWRLVYEHSSKGTTQPLDITSLSVEQKDLFRDLHKTIAKVTD  714
            ++ W E ++EG+ +FL RV RL+   ++K  T+         +   L +  + T+  VT+
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLI---TTKEITEE--------NSGALDKVYNETVKAVTE  694

Query  715  DVGRRQAFNTAIAAIMELMNKLTRASQETDQDRALMQEALLAVVRMLSPIIPHACFIMWQ  774
            +V++ + FNTAIA +M ++N        ++++  L  +   + V++++P+ PH    +WQ
Sbjct  695  QVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  775  ALGGKGD-IDIADWPQADEQAMVDDTKLVVIQVNGKVRGRVTVPADATKEHVHDMAAKEY  833
            AL + G+ I    WP  DE  +V++   +V+Q++GKV++++ V+ D ++E+++++A  + 
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  834  GVAKYLEGVTIRKVIYVPGKLLNLVV  859
             V   + G  I KVI VP KL+N+V+
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVI  832

1472) leuS in NC_017530


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  518 bits (1954),  Expect = 7e-148, Method: Compositional matrix adjust.
 Identities = 361/884 (41%), Positives = 549/884 (63%), Gaps = 74/884 (8%)

Query  5    YTPRDIEAAAQKFWDEQQSFAVTEQPGKDTYYCLSMFPYPSGK-LHMGHVRNYTIGDVIA  63
            Y    IE+  Q FW ++++F    +++K  +Y L MFPYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPMGWDAFGMPAENAAMKNNVAPAKWTYENIDYMKTQLKSLGLAIDWAR  123
            R++R  G NVL+PMGWDAFG+PAE+ AM     PA  T ENI   K Q+++LG++ DW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVTTCKPDYYRWEQWLFTRLFEKGIIYRKNGTVNWDPADQTVLANEQVI-DGRGWRSGAL  182
            EV T  P+YY+W QW+FT+L+EKG+ Y  +  VNW     T +ANE+V+ DG + R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  IEKREIPMYYFRITDYADELLESLDELPGWPEQVKTMQRNWIGKSRGMEVQFPYDKASIG  242
            + ++ +    ++IT YA+ LLE L+E+ +WPE +K MQRNWIGKS G +V F    +   
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDT---  239

Query  243  HEGTLKVFTTRPDTLMGATYVAVAAEHPLATQAAQGNPALQAFIDECKSGSVAEADMA--  300
             +  + VFTTRPDTL GATY  +A+EH+L    + ++ A    + + K  +   +D+A  
Sbjct  240  -DKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQA--EAVADYKRQASLKSDLART  296

Query  301  --TQEKKGMATSLLVEHPLTGEKLPVWVANYVLMHYGDGAVMAVPAHDERDFEFAHKYNL  358
              ++EK G+ T+    +P+ G  +PVW+A+YVL  YG GA+MAVPAHDERD EFA ++NL
Sbjct  297  DLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNL  356

Query  359  PVKAVVRTSAGDEVGSEWQAAYGEHGQLINSAEFDGLDFAGAFDAIEAALIRKELGKSRT  418
             + +V+  +  +E      AA+ E+G  INS  +DGLD A+A+  +   L    +G+   
Sbjct  357  DIIPVLEGGNVEE------AAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENV  410

Query  419  QFRLRDWGISRQRYWGCPIPIIHCPSCGDVPVPEDQLPVTLP--ENVVPDGAG-SPLARM  475
             +RLRDW +SRQRYWG PIPIIH       +VPE +LP+ LP   ++ P G+G SPLA +
Sbjct  411  TYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANV  470

Query  476  PEFYECSCPKCGAAAKRETDTMDTFVESSWYFARYASPNYDKGLVDPKAANHWLPVDQYI  535
             +  E +    G  ++RET+TM     SSWY+ RY  P+    L D    ++WLPVD Y+
Sbjct  471  TDWLEVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYV  529

Query  536  GGIEHAILHLLYARFFHKLMRDEGLVTSNEPFKNLLTQGMVVAETYYRVASNGGKDWFNP  595
            GG EHA+LHLLYARF HK++ D G+V ++EPF++L+ QGM+++ +Y              
Sbjct  530  GGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY--------------  575

Query  596  ADVEIERDAKAKIIGARL--KTDG--LPVEIG-----GTEKMSKSKNNGVDPQSMIEAYG  646
                  RD+++ ++++    K DG  + VE G     +  KMSKS +N V+P+ ++E YG
Sbjct  576  ------RDSRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYG  629

Query  647  ADTCRLFMMFASPPDMSLEWSDSGVEGASRFLRRVWRLAQA-HVSQGLPGKLDVAALDDA  705
            ADT R++ MF +P D S+ WS+ G+EG+ +FL RV RL  + ++++  +G LD       
Sbjct  630  ADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALD-------  682

Query  706  QKVIRRAIHAAIKQASTDVGQFHKFNTAIAQVMTVMNVLEKAPQATEQDRALLQEGLEAV  765
                 +  + ++K  + +V+Q  KFNTAIAQ+M  +N       A++++  L+ +   + 
Sbjct  683  -----KVYNETVKAVTEQVDQM-KFNTAIAQLMVFVN-------AANKEDKLFSDYAKGF  729

Query  766  TLLLAPITPHISHALWQHLGHAGSVID-AAWPSVDEQALVQDSITLVVQVNGKLRGQVEM  824
              L+AP++PH+++ LWQ L  +G  I   +WPS DE  LV++ + +VVQ++GK+++++ +
Sbjct  730  VQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVV  789

Query  825  PaaasreeveaaarsnenvLRFIDGLTIRKVIVVPGKLVNIVAN  868
            +   SREE++  A +NE+V   I G  I KVI VP KLVNIV +
Sbjct  790  AKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

1473) leuS in NC_002947


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  518 bits (1954),  Expect = 7e-148, Method: Compositional matrix adjust.
 Identities = 361/884 (41%), Positives = 549/884 (63%), Gaps = 74/884 (8%)

Query  5    YTPRDIEAAAQKFWDEQQSFAVTEQPGKDTYYCLSMFPYPSGK-LHMGHVRNYTIGDVIA  63
            Y    IE+  Q FW ++++F    +++K  +Y L MFPYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPMGWDAFGMPAENAAMKNNVAPAKWTYENIDYMKTQLKSLGLAIDWAR  123
            R++R  G NVL+PMGWDAFG+PAE+ AM     PA  T ENI   K Q+++LG++ DW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVTTCKPDYYRWEQWLFTRLFEKGIIYRKNGTVNWDPADQTVLANEQVI-DGRGWRSGAL  182
            EV T  P+YY+W QW+FT+L+EKG+ Y  +  VNW     T +ANE+V+ DG + R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  IEKREIPMYYFRITDYADELLESLDELPGWPEQVKTMQRNWIGKSRGMEVQFPYDKASIG  242
            + ++ +    ++IT YA+ LLE L+E+ +WPE +K MQRNWIGKS G +V F    +   
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDT---  239

Query  243  HEGTLKVFTTRPDTLMGATYVAVAAEHPLATQAAQGNPALQAFIDECKSGSVAEADMA--  300
             +  + VFTTRPDTL GATY  +A+EH+L    + ++ A    + + K  +   +D+A  
Sbjct  240  -DKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQA--EAVADYKRQASLKSDLART  296

Query  301  --TQEKKGMATSLLVEHPLTGEKLPVWVANYVLMHYGDGAVMAVPAHDERDFEFAHKYNL  358
              ++EK G+ T+    +P+ G  +PVW+A+YVL  YG GA+MAVPAHDERD EFA ++NL
Sbjct  297  DLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNL  356

Query  359  PVKAVVRTSAGDEVGSEWQAAYGEHGQLINSAEFDGLDFAGAFDAIEAALIRKELGKSRT  418
             + +V+  +  +E      AA+ E+G  INS  +DGLD A+A+  +   L    +G+   
Sbjct  357  DIIPVLEGGNVEE------AAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENV  410

Query  419  QFRLRDWGISRQRYWGCPIPIIHCPSCGDVPVPEDQLPVTLP--ENVVPDGAG-SPLARM  475
             +RLRDW +SRQRYWG PIPIIH       +VPE +LP+ LP   ++ P G+G SPLA +
Sbjct  411  TYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANV  470

Query  476  PEFYECSCPKCGAAAKRETDTMDTFVESSWYFARYASPNYDKGLVDPKAANHWLPVDQYI  535
             +  E +    G  ++RET+TM     SSWY+ RY  P+    L D    ++WLPVD Y+
Sbjct  471  TDWLEVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYV  529

Query  536  GGIEHAILHLLYARFFHKLMRDEGLVTSNEPFKNLLTQGMVVAETYYRVASNGGKDWFNP  595
            GG EHA+LHLLYARF HK++ D G+V ++EPF++L+ QGM+++ +Y              
Sbjct  530  GGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY--------------  575

Query  596  ADVEIERDAKAKIIGARL--KTDG--LPVEIG-----GTEKMSKSKNNGVDPQSMIEAYG  646
                  RD+++ ++++    K DG  + VE G     +  KMSKS +N V+P+ ++E YG
Sbjct  576  ------RDSRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYG  629

Query  647  ADTCRLFMMFASPPDMSLEWSDSGVEGASRFLRRVWRLAQA-HVSQGLPGKLDVAALDDA  705
            ADT R++ MF +P D S+ WS+ G+EG+ +FL RV RL  + ++++  +G LD       
Sbjct  630  ADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALD-------  682

Query  706  QKVIRRAIHAAIKQASTDVGQFHKFNTAIAQVMTVMNVLEKAPQATEQDRALLQEGLEAV  765
                 +  + ++K  + +V+Q  KFNTAIAQ+M  +N       A++++  L+ +   + 
Sbjct  683  -----KVYNETVKAVTEQVDQM-KFNTAIAQLMVFVN-------AANKEDKLFSDYAKGF  729

Query  766  TLLLAPITPHISHALWQHLGHAGSVID-AAWPSVDEQALVQDSITLVVQVNGKLRGQVEM  824
              L+AP++PH+++ LWQ L  +G  I   +WPS DE  LV++ + +VVQ++GK+++++ +
Sbjct  730  VQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVV  789

Query  825  PaaasreeveaaarsnenvLRFIDGLTIRKVIVVPGKLVNIVAN  868
            +   SREE++  A +NE+V   I G  I KVI VP KLVNIV +
Sbjct  790  AKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

1474) leuS in NC_020520


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  517 bits (1951),  Expect = 1e-147, Method: Compositional matrix adjust.
 Identities = 339/747 (46%), Positives = 504/747 (68%), Gaps = 67/747 (8%)

Query  220  DHRLAYVSDAPVNWCPGLGTVVANEEVTADGRSDRGNFPVFKRNMRQWMMRITKYADRLI  279
            +  LAY ++ PVNW   LGT +ANEEV +DG S+RG +PV ++ MRQWM++IT YA+RL+
Sbjct  145  EKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLL  204

Query  280  DDLELLDWTDAIKAMQRNWIGRSQGAKVDFA--SPAGDITVFTTRPDTLFGASFMVLSPE  337
            +DLE +DW ++IK MQRNWIG+S GA+V F       D+TVFTTRPDTLFGA++ VL+PE
Sbjct  205  EDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPE  264

Query  338  HPFVDELADAGQTDAIAAYRGQAAAKKDFERQDDTREKTGVFTGAYATNPVNGEQIPIWI  397
            H++VD ++ ++Q++A+A Y+ QA+ K D+ R D ++EKTGV TG+YA NPVNG ++P+WI
Sbjct  265  HALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAINPVNGKEMPVWI  324

Query  398  ADYVLMGYGTGAIMAVPSGDERDFEFARKFDLpipaiqqppaaWFEEHGIEPTLDTSVWP  457
            ADYVL +YGTGAIMAVP+ DERD EFA++F+L                +I P L+ +   
Sbjct  325  ADYVLASYGTGAIMAVPAHDERDWEFAKQFNL----------------DIIPVLEGGN--  366

Query  458  TAYIGDAPYVQSA---NDELDLNGIDNKAEGIEKMNAWLEAKGAGEATINYKLRDWLFSR  514
               + +A++ + +   N ++ L+G+D KA +I KM  WLEA G G+  + Y+LRDWLFSR
Sbjct  367  ---VEEAAFTEDGLHINSDF-LDGLD-KASAIAKMVEWLEAEGVGNENVTYRLRDWLFSR  421

Query  515  QRYWGEPFPIVYDDEGRPHTIPDELLPVELPETDQFSPRTFEPDDAMSNPESPLDRLQDW  574
            QRYWGEP+PI+  ++G + ++P+  LP+ LP T ++ P         +  ESPL  + DW
Sbjct  422  QRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPS--------GTGESPLANVTDW  473

Query  575  VNIELDLGDGRGVQTYRRDTNVMPQWAGSCWYQLRYIDPTNDERFCARENEEYWMGPRTD  634
                L++    GV+  RR+TN MPQWAGS WY LRYIDP N E++   E    W+     
Sbjct  474  ----LEVTREDGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWL-----  523

Query  635  VRPDHPGGIDLYVGGVEHAVLHLLYARFWHKVLFDLGHVSSVEPYARLFNQGYIQAAAFK  694
                    +D+YVGG EHAVLHLLYARFWHKVL+DLG V++ EP+ +LFNQG I +++++
Sbjct  524  -------PVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYR  576

Query  695  DEREIYVEATEVEGDADSGFTYH---GEPVTREWGKMGKSLKNAVSPDEMYEAYGADTLR  751
            D R   V +  VE   D++F +H   GE + +  +KM+KSLKN V+PD++ E YGADTLR
Sbjct  577  DSRGALVATDKVE-KRDGSF-FHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLR  634

Query  752  LYEMAMGPLDASRPWETRDVVGMYRFLQRLWRNMVDEESGECIVTDEPADTDTLKLLHRT  811
            +YEM MGPLDAS +W   ++ G  +FL+R+ R +   E    I  ++++  D  K+ + T
Sbjct  635  VYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKE----ITEENSGALD--KVYNET  688

Query  812  IDTVRTEMDALRFNTAIAKLIELNNAVTKLDSMPREIAEPMVTMLAPLVPHIAEELWKRL  871
            + +V  ++D ++FNTAIA+L+ + NA  K D +  + A   V ++AP+ PH++EELW+ L
Sbjct  689  VKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQAL  748

Query  872  GRSADSDGTVTYVEFPVADPAMLVDDTIEMPIQINGKVRSKIEVAADAGNddveaaalad  931
              S++S   ++YV  P  D + LV++ +E+ +QI+GKV++K+ VA D + ++++  ALA+
Sbjct  749  TASGES---ISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALAN  805

Query  932  akvvealaGGEPKKLIVVPGRMINVVV  958
             KV   +AG +  K+I VP +++N+V+
Sbjct  806  EKVQAEIAGKDIIKVIAVPNKLVNIVI  832


 Score =  134 bits (491),  Expect = 3e-32, Method: Compositional matrix adjust.
 Identities = 77/149 (52%), Positives = 103/149 (70%), Gaps = 11/149 (7%)

Query  25   SIEVGWQDWWDEHGTFETPNPVGPLADPDEVAARGEKLFVQDMFPYPSGVGLHVGHPLGF  84
            +IE  WQ  W ++ TF T              A   K++  DMFPYPSG GLHVGHP G+
Sbjct  8    AIEPKWQAFWADNHTFKTGT-----------DASKPKFYALDMFPYPSGAGLHVGHPEGY  56

Query  85   IGTDVFSRYKRMTGHNVLYTMGFDAFGLPAEQFAVQTGTHPAITTDANIANMRRQLRRLG  144
             +TD++SR+KR  GHNVL  MG DAFGLPAEQ+A++TG +PA  T  NIAN +RQ+  LG
Sbjct  57   TATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALG  116

Query  145  LSHDVRRSISTTDPDYYRWTQWIFSQIFN  173
            +S D  R ++TTDP+YY+WTQWIF+++++
Sbjct  117  FSYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1475) leuS in NC_008025


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  517 bits (1950),  Expect = 1e-147, Method: Compositional matrix adjust.
 Identities = 373/848 (44%), Positives = 529/848 (63%), Gaps = 60/848 (7%)

Query  14   YNPHAIEPKWQARWEQEGLYTFHEDPSKTKHYALTMFPYPSG-NLHIGHWYANVAPDAHA  72
            Y+  AIEPKWQA W ++  +    D+SK K YAL MFPYPSG  LH+GH  +  A D  +
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  73   RWMRMRGYNVFFPMGFDAFGLPAENAAIKHGLNPATWTSSNIEHMLGQFKRMGTMIDWSR  132
            R  R +G NV+ PMG DAFGLPAE+ A+  G +PA  T+ NI +   Q++ +G   DW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  133  SLATCDPEYYRWNQWFFTEFFRRGLAYKKDGLVNWCPKDQTVLANEQVV-DGRCERCGTP  191
             + T DP+YY+W QW+FT ++ +GLAY  +  VNW     T +ANE+V+ DG  ER G P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  192  VERRNLSQWYLKITDYAEELL-DFRDTDMPERVRAMQTNWIGKSVGAEITFDTPAGPE--  248
            V R+ + QW LKIT YAE LL D+ + D PE ++ MQ NWIGKS GA++TF         
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  249  TVFTTRPDTLMGATFLVLAPEHPKVPALTTPEQAEAVRAYVEAAGRKTDVERQQELGEKT  308
            TVFTTRPDTL GAT+ VLAPEH+ V A+TT++QAEAV  Y   A+ K+D+ R +   EKT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  309  GVFTGSYATHPVTGHQIPIWVADYVLMTYGTGSIMAVPAHDERDFDFARKFGLEIREVIR  368
            GV TGSYA +PV G ++P+W+ADYVL +YGTG+IMAVPAHDERD +FA++F L+I  V+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL-  362

Query  369  PEGGEPLDTTQAPYVGEGVIVNSGEFDGLPGGKASIAPIIARLEALGVAKPKTTYRLRDW  428
             EGG   +  +A++  +G+ +NS+ +DGL  + ++IA ++ +LEA GV++ + TYRLRDW
Sbjct  363  -EGG---NVEEAAFTEDGLHINSDFLDGLDKA-SAIAKMVEWLEAEGVGNENVTYRLRDW  417

Query  429  LVSRQRYWGTPIPIVYCPDHGAQPVPADQLPVKLPENVEFMP--TGQSPLKLDREWMRAT  486
            L SRQRYWG PIPI+   D  + +VP  +LP+ LP   ++ P  TG+SPL    +W+  T
Sbjct  418  LFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT  477

Query  487  CPVCGGPAERDTDTMDTFVDSSWYMYRYLSPHDDQHPFDPAHANL-LPVDLYTGGIEHAI  545
                G  + R+T+TM    +SSWY  RY+ PH+ +   D    +  LPVD+Y GG EHA+
Sbjct  478  RE-DGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  546  LHLLYSRFWTKVMRDMGLTVQNEPFARLRNQGIILG------------------------  581
            LHLLY+RFW KV+ D+G+   +EPF +L NQG+ILG                        
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFF  596

Query  582  ---------EDGEKMSKSRGNVVDPDDLVREYGADTVRTYLMFIAPWELGGPWDPSGING  632
                     +   KMSKS  NVV+PDD+V +YGADT+R Y MF++P + + +W   G++G
Sbjct  597  HVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEG  656

Query  633  PAKWLSRVWALYFDEKAAGPEEKIGEADLRYAVHSTLKKVGADYERMSFNTIIAALMELT  692
            + K L RV  L         EE+ G  D  Y  + T+K V  + ++M FNT IA LM + 
Sbjct  657  SRKFLDRVYRLI--TTKEITEENSGALDKVY--NETVKAVTEQVDQMKFNTAIAQLMVFV  712

Query  693  NTLVKAKRSPVFGTPAWEEALDIFNRMLAPVAPHIAEEIWRE-RGGTESVHLQAWPAVDE  751
            N+  K  +  +F+     +    F +++AP APH++EE+W+   ++ ES+   +WP+ DE
Sbjct  713  NAANKEDK--LFS-----DYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDE  765

Query  752  AAATRDTVTIGVQVSGKIRGEVQISKtataeealaaaraHPDVAKFTEGKQTIKEIYVPG  811
            +    + V I VQ+ GK+++ + ++K  + EE    A A+  V     GK+ IK I VP 
Sbjct  766  SKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPN  825

Query  812  RIINIVVK  819
            +++NIV+K
Sbjct  826  KLVNIVIK  833

1476) Pat9b_1072 in NC_014837


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  516 bits (1948),  Expect = 2e-147, Method: Compositional matrix adjust.
 Identities = 360/865 (42%), Positives = 549/865 (64%), Gaps = 46/865 (5%)

Query  5    YRPEEIESRVQQHWDENETFKVTEQEGKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIA  63
            Y    IE++ Q  W +N+TFK   + +K K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIQYMKNQLKLLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NI   K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCQPEYYRWEQWFFTKLYEKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T +P+YY+W QW+FTKLYEKGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFVKITDYAeellndldtledWPEQVKTMQRNWIGRSEGVEITFNVANSDEK  242
            V RK + QW +KIT YA E L +     DWPE +K MQRNWIG+S G ++TF+V ++D  
Sbjct  184  VVRKPMRQWMLKITAYA-ERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  VTVYTTRPDTFMGATY--VavaaghplaqqaaaRNPALVDFIDECR-NTKVAEADMATME  299
             TV+TTRPDT+ GATY  +A   +   A  ++ +  A+ D+  +   ++ +A +D+A  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGMATGLHAIHPLTGEEIPVWVANFVLMEYGTGAVMAVPGHDQRDWEFATKYDLAIKPV  359
            K G+ TG  AI+P+ G E+PVW+A++VL  YGTGA+MAVP+HD+RDWEFA +++L I PV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  360  ILNLDGTAPDLSAAAMTEKGTLFNSGEYDGLDHQAGFNAIADALTAKGVGVRKVNYRLRD  419
               L+G   ++  AA TE G  +NS+  DGLD  +++  + + L A GVG  +V YRLRD
Sbjct  362  ---LEGG--NVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMVTLEDGTVMPTPEDQLPVILP--EDVVMDGIT-SPIKADPEWAKT  476
            W  SRQRYWG PIP++  EDGT  + PE +LP++LP   D+   G   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  T-VNGQPALRETDTFDTFMESSWYYARYTCANYNEGMLDPAAANYWLPVDQYVGGIEHAI  535
            T  +G  + RET+T      SSWYY RY  ++  E + D    + WLPVD YVGG EHA+
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLMYFRFYHKLLRDAGLVNSNEPAKRLLCQGMVLADAFYYVGANGERNWVSPVDVNVER  595
            +HL+Y RF HK+L D G+V ++EP ++L+ QGM+L+ +  Y ++ G         V  ++
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS--YRDSRGAL-------VATDK  587

Query  596  DEKGRIVKAIDNQGREVVYAGMSKMSKSKNNGIDPQLMVERYGADTVRLFMMFASPAEMT  655
             EK R    ++ +  E +  + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P + +
Sbjct  588  VEK-RDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  656  LEWQESGVEGANRFLKRVWKLAYDHVAKGATVALDVNALNDDQKALRRDLHKTIAKVADD  715
            + W E G+EG+ +FL RV +L     +K  T        +++  AL +  + T+  V+++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLI---TTKEIT--------EENSGALDKVYNETVKAVTEQ  695

Query  716  IGRRQTFNTAIAAIMELMNKLIRAPQESEQDRALLQEALVAVTRLLYPFTPHTSYALWEA  775
            +++ + FNTAIA +M ++N        ++++  L+ +   +  +L+ PF+PH +  LW+A
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  776  LGGEGN-IDDASWPVADEAAMVEDSLLVVVQVNGKVRGKITVAPDATQEQVQARAAQEHL  834
            L + G+ I   +WP  DE+ +VE+ + +VVQ++GKV++K+ VA D ++E++Q  A  ++ 
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  835  VAKYLEGVTIRKVIYVPGKLLNLVV  859
            V   + G  I KVI VP KL+N+V+
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVI  832

1477) leuS in NC_014366


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  516 bits (1948),  Expect = 2e-147, Method: Compositional matrix adjust.
 Identities = 343/855 (41%), Positives = 528/855 (62%), Gaps = 70/855 (8%)

Query  5    YHPEQVEAAAQQYWEDHQTFLAREIPGKEKFYCLSMFPYPSGR-LHMGHVRNYTIGDVMS  63
            Y+   +E+  Q +W D++TF +   ++K KFY L MFPYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   HFQRMQGKSVLQPMGWDAFGLPAENAAIKNNVAPAKWTYENIDYMRKQLKRLGFSYDWSR  123
            +F+R QG +VL+PMGWDAFGLPAE+ A+     PA  T ENI   ++Q++ LGFSYDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCNPKYYRWEQWFFTKLFEKGLVYKKSSMVNW-DPVDQTVLANEQVVDGKGWRSGAT  182
            E+ T +P+YY+W QW+FTKL+EKGL Y     VNW + ++ ++  +E + DG + R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERREIPQWFLKITAYAEELLTDLDKLEGWPEQVKTMQRNWIGRSEGVELDFATEEGA-A  241
            V R+ + QW LKITAYAE LL DL+ ++ WPE +K MQRNWIG+S G ++ F   +    
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  242  LRVFTTRPDTLMGVTY--VaiaaqhaiakaaaeenpaiaDFLRECNATKTAEADMATMEK  299
            + VFTTRPDTL G TY  +A       A +++++  A+AD+ R+ +          + EK
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEK  302

Query  300  KGIFTGRHAIHPLSGKKVPIWIANFVLMEYGQGAVMAVPGHDQRDYEFACKHQLPIQQVI  359
             G+ TG  AI+P++GK +P+WIA++VL  YG GA+MAVP+HD+RD EFA + +L   ++I
Sbjct  303  TGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNL---DII  359

Query  360  APLNDEPIDLGKEAFVSKGQLINSGEFDGLNFDQAFQAIAKRLVDEKKGAITINYRLRDW  419
            + L++  ++    AF   G  INS+ +DGL+   A+  +  +L  E  G   + YRLRDW
Sbjct  360  PVLEGGNVE--EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDW  417

Query  420  GVSRQRYWGCPIPIINCASCGAVAVPEKDLPVVLP--EDVEFDGVG-SPIKKMPSFYQTT  476
              SRQRYWG PIPII+     + AVPE +LP+VLP   D+   G G SP+ ++    + T
Sbjct  418  LFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT  477

Query  477  CPKCGGTAERETDTFDTFMESSWYFARFSCRDQSQSMLDAR-SDYWLSVDQYIGGIEHAI  535
                G  + RET+T      SSWY+ R+   ++++ + D      WL+VD Y+GG EHA+
Sbjct  478  RED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  LHLLYARFFHKLMRDQGLTQSHEPFTRLLTQGMVL-------------------KDG---  573
            LHLLYARF HK++ D G+  + EPF +L+ QGM+L                   +DG   
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFF  596

Query  574  ------------AKMSKSKGNTVDPQALIDQYGADTVRLFTMFAAPPEQSLEWSDSGVEG  621
                        AKMSKS  N V+P+ +++QYGADT+R++ MF +P + S+ WS+ G+EG
Sbjct  597  HVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEG  656

Query  622  ASKFLRRLWRLVHAKALAGRPAALDTSALTSNEQDLRRKTHETLQKVYDDFARRFTYNTA  681
            + KFL R+ RL+ +K ++   ++            L +  +ET++ V ++   +  +NTA
Sbjct  657  SRKFLDRVYRLITTKEITEENSG-----------ALDKVYNETVKAVTEQ-VDQMKFNTA  704

Query  682  IAAVMELLNAVSRFEDTSPQSGAIVHEALESIVIMLAPITPHICHTLWQHL-GHSEALAY  740
            IA +M ++NA ++        + +  +   ++V ++AP++PH+ + LWQ L + +E+++Y
Sbjct  705  IAQLMVFVNAANK-------EDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISY  757

Query  741  TAWPAVDPTALARAEVELVVQVNGKVRGKIHLPIEADQATAENTALQNENVIRFIEGKPV  800
             +WP+ D + L   +VE+VVQ++GKV++K+ ++ +  +   ++ AL NE+V   I GK +
Sbjct  758  VPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDI  817

Query  801  RKIIVVPGKLVNIVV  815
             K+I VP KLVNIV+
Sbjct  818  IKVIAVPNKLVNIVI  832

1478) leuS in NC_012982


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  516 bits (1947),  Expect = 2e-147, Method: Compositional matrix adjust.
 Identities = 348/865 (41%), Positives = 546/865 (64%), Gaps = 46/865 (5%)

Query  5    YNAREVEPKWQKAWADAQIFEAKTPAEAGDMPKAYVLEMFPYPSGR-LHMGHVRNYAMGD  63
            Y+   +EPKWQ  WAD + F  KT ++A+  PK Y L+MFPYPSG  LH+GH   Y+  D
Sbjct  4    YDHTAIEPKWQAFWADNHTF--KTGTDAS-KPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  64   VVARFHISNGYNVLHPMGWDAFGMPAENAAMEKGAQPGVWTHENIDAMKEQFSPLGLSLD  123
            +++RF  ++G NVLHPMGWDAFG+PAE+ AM+ G +P+  T ENI   K Q+++LG+S D
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  124  WKREFATCDADYYGQQQKIFLKFWENNLVFRKKSKVNWDPVDNTVLANEQVI-DGKGWRS  182
            W RE  T D++YY   Q IF K+ E+ L +     VNW     T +ANE+V+ DG + R+
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  183  GAIVEQRELEQWTLKITHYAEDLLKGLDSLDRWPEKVRTMQANWIGKSLGATFTWPFAGE  242
            G  V ++ + QW LKIT YAE LL +L+ +D WPE ++ MQ NWIGKS GA  T  F   
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVT--F---  234

Query  243  APKGHEKGIDVFTTRPDTLFGASFVALAPDHAITKELAKTNP--KIAAFITEAA-KGGTT  299
              K+ +K++ VFTTRPDTLFGA++  LAP+HA+   ++ ++    +A +  +A+ K++ +
Sbjct  235  KVKDTDKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLA  294

Query  300  EEAIEKAPKLGIDLGLKVKHPFNPEWEIPVWSANFVLSTYGSGAVFGSPAGDQRDLDFAR  359
               + K  K G+  G    +P N   E+PVW A++VL++YG+GA+ + PA D+RD +FA+
Sbjct  295  RTDLAKE-KTGVWTGSYAINPVNGK-EMPVWIADYVLASYGTGAIMAVPAHDERDWEFAK  352

Query  360  KYDLPVIPVVLPANADPETYTIENEAYTGTGTLFNSKFLDGLSTSEGIKAAIAKLEELGL  419
            +++L +IPV+  +N       +E+ A+T  G  +NS FLDGL  + +I   +  LE  G+
Sbjct  353  QFNLDIIPVLEGGN-------VEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGV  405

Query  420  GSSSTTYRLRDWGISRQRYWGCPIPAIRCDDCGVVPVPEDQLPIKLPDDPDFSAPG---N  476
            G+ + TYRLRDW +SRQRYWG PIP I+ +D    +VPE +LP+ LP   D+ ++G   +
Sbjct  406  GNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGES  465

Query  477  PLDRHPTWKHTTCPKCAKPATRETDTLDTFMDSSWYFARFCDSDSIEPVNKEA-ASYWLP  535
            PL     W + T     K + RET+T+    +SSWY+ R+ D+++ E +  E     WLP
Sbjct  466  PLANVTDWLEVTREDGVK-GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLP  524

Query  536  VDQYIGGVEHAILHLLYSRFFTRAMHDCGIIDLPAGEPFAGLFTQGMVTHETYKSSEGKW  595
            VD Y+GG EHA+LHLLY+RF  + + D G++  P+ EPF  LF QGM+   +Y+ S G  
Sbjct  525  VDIYVGGAEHAVLHLLYARFWHKVLYDLGVV--PTKEPFQKLFNQGMILGTSYRDSRGAL  582

Query  596  LSPEDIEERDGNLVELETGKPVSVGQIEKMSKSKKNVVDPSIIIGDYGADVARWFVLSDS  655
            ++ + +E RDG++ ++ETG  +  +   KMSKS KNVV+P  ++ +YGAD  R + +  +
Sbjct  583  VATDKVEKRDGSFFHVETGEELEQAP-AKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMG  641

Query  656  PPERDVEWTQSGAEGAWKFIQKLWSLAEAGPAEDDGEIGDGAASELLRATHKTIDGVTRG  715
            P +  + W++ G EG++KF++++  L  +       EI +  ++ L +  + T+ +VT  
Sbjct  642  PLDASIAWSEEGLEGSRKFLDRVYRLITT------KEITEENSGALDKVYNETVKAVTEQ  695

Query  716  IKDFRFNTSVAQIHEFSNTLKKAENAKGPGIATARRFALKTLAQLVSPFAPHVAEESWAA  775
            + + +FNT++AQ+  F N+ +K ++           +A K + QL++PFAPH++EE W A
Sbjct  696  VDQMKFNTAIAQLMVFVNAANKEDK-------LFSDYA-KGFVQLIAPFAPHLGEELWQA  747

Query  776  LGGEG-LVSSAPWPIADEKLMTSDTLTMPVQVNGKKRGEIEVDKSATKDAVEEIALSDPK  834
            L + G  +S  PWP  DE  +  + + + VQ++GK ++ + V K  +++ ++E+AL++ K
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  835  VAAFLADKTVKKIIVVPGRIVNIVI  859
            V A +A+K + K+I VP ++VNIVI
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVI  832

1479) Nhal_0537 in NC_013960


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  516 bits (1946),  Expect = 3e-147, Method: Compositional matrix adjust.
 Identities = 356/859 (42%), Positives = 530/859 (62%), Gaps = 73/859 (8%)

Query  5    YQATQIEAEAQAYWEQHQSFRVIEDSTREKFYCLSMFPYPSGR-LHMGHVRNYTIGDVIA  63
            Y+ T IE+  QA+W ++++F+   D+++ KFY L MFPYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMGGKNVLQPMGWDAFGLPAENAAMQNRVPPDQWTYQNIDYMRGQLKRLGFAYDWSR  123
            R++R  G NVL+PMGWDAFGLPAE+ AM+    P + T +NI   + Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCHPAYYHWEQWLFTKLFDKGLVYKKTALVNW-DPVDQTVLANEQVVDGRGWRSGAV  182
            E+ T +P YY W QW+FTKL++KGL Y     VNW + ++ ++  +E + DG + R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERREIPQWFLKITAYAEELLTGLDQLSGWPEQVRTMQRNWIGRSEGVEVQFQV-EGRAP  241
            V R+ + QW LKITAYAE LL +L+++ +WPE ++ MQRNWIG+S G +V F+V +    
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  242  LLVFTTRPDTLMGVTFVSVAAEHSLAREAAKTNPALAAFIEECQHTVTSEAVLETL--EK  299
            + VFTTRPDTL G T+  +A+EH+L    + ++ A A      Q ++ S+     L  EK
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEK  302

Query  300  KGMDTGLKAVHPLTGETIPIWVANFVLMSYGTGAVMAVPAHDQRDYEFAQVYGLPIQQVI  359
             G+ TG  A++P+ G  +P+W+A++VL SYGTGA+MAVPAHD+RD EFA+ + L I  V+
Sbjct  303  TGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL  362

Query  360  APQDDQSACHLEQAAFVEKGVLINSGQFTGLDFEQAFAAIAQHLEGQGKGQRVVNYRLRD  419
                   + ++E+AAF E G+ INS+ + GLD   A+A + + LE++G G+  V YRLRD
Sbjct  363  E------GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPVIN--CPSCGAvpvpeeelpvvlpeGVRFDGV-RSPLKQMPEFYQT  476
            W  SRQRYWG PIP+I+    +  AVP +E  L + +  ++R  G   SPL ++ +  + 
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  TCPRCGENAERETDTFDTFFESSWYYARYCCPDNDAAMVDER-GHYWLPVDQYIGGIEHA  535
            T    G ++ RET+T      SSWYY RY  P+N   + DE     WLPVD Y+GG EHA
Sbjct  477  TRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  536  VLHLLYARFFHKVMRDMGLVRGDEPFTHLLTQGMVL-------------------KDG--  574
            VLHLLYARF HKV+ D+G+V   EPF  L+ QGM+L                   +DG  
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSF  595

Query  575  -------------AKMSKSKGNTVDPQALIEQYGADTARLFIMFAAPPEQSLEWSESGVE  621
                         AKMSKS  N V+P+ ++EQYGADT R++ MF +P + S+ WSE G+E
Sbjct  596  FHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLE  655

Query  622  GAHRFLKRLWRMVATHVAQRQGSVPPLEVKTLSAEQKLLRTKVHETIVKASDDIGRRYTF  681
            G+++FL R+ R+++T              K ++ E+     KV +  VKA  +   +  F
Sbjct  656  GSRKFLDRVYRLITT--------------KEITEENSGALDKVYNETVKAVTEQVDQMKF  701

Query  682  NTAIAAVMELMNALAKLDDDTPQGQAVRQETLETVVLLLSPITPHICHRLWRELGHEGAV  741
            NTAIA +M ++NA  K        + +  +     V L++P++PH+ + LW+ L   G  
Sbjct  702  NTAIAQLMVFVNAANK-------EDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGES  754

Query  742  ID-ASWPEADPAALVKETVDLVVQVNGKRRGQITVAAEASREVIEAQAQSEPNVQRFIEG  800
            I   +WP  D + LV + V++VVQ++GK ++++ VA + SRE ++  A ++ +VQ  I G
Sbjct  755  ISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAG  814

Query  801  KTVRKVILVPHRLVNLVVR  819
            K + KVI VP++LVN+V++
Sbjct  815  KDIIKVIAVPNKLVNIVIK  833

1480) Ndas_3332 in NC_014210


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  516 bits (1946),  Expect = 3e-147, Method: Compositional matrix adjust.
 Identities = 356/850 (42%), Positives = 542/850 (64%), Gaps = 62/850 (7%)

Query  18   ALQDKWQARWAAELPFQADEDPGDTRPRSYIVDMFAYPSG-DLHMGHAEAYAIGDVISRY  76
            A++ KWQA WA +  F+++ D+  ++P+ Y +DMF+YPSG +LH+GH+E+Y+  D++SR+
Sbjct  8    AIEPKWQAFWADNHTFKTGTDA--SKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSRF  65

Query  77   RLQRGDNVLHPVGWDSFGLPAENAAIKNNSHPAEWTYANIETQAASFRRYGISVDWSRRL  136
            +  +G+NVLHP+GWD+FGLPAE+ A+   ++PAE T  NI      +   G+S DW R +
Sbjct  66   KRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDREV  125

Query  137  HTSDPEYYRWNQWLFTRFFERGLAYRKDGHVNWCPQDQTVLANEQVV-QGRCERCGADVV  195
            +T+DP+YY+W QW+FT+++E+GLAY  +  VNW  +  T +ANE+V+ +G  ER G  VV
Sbjct  126  NTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVV  185

Query  196  RRSLNQWYFRITDYAQRllddmdqlddGRWPDEILAMQRNWIGRSTGADVHFAIEGRDEP  255
            R+++ QW ++IT YA+RLL+D++++D   WP+ I  MQRNWIG+STGA+V F + + D  
Sbjct  186  RKPMRQWMLKITAYAERLLEDLEEVD---WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  256  VTVFTTRPDTLYGATFFVVaadadladELCAPEQREAFDAYRADVAKLSDIERQATERPK  315
             TVFTTRPDTL+GAT+ V+A++  L D + +++Q EA   Y+ + +  SD+ R    + K
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEK  302

Query  316  TGVFLGRYAINPVNGERMPVWAADYVLADYGHGAIMAVPAHDQRDLDFALAFDLPVRVVV  375
            TGV  G YAINPVNG  MPVW ADYVLA YG GAIMAVPAHD+RD +FA  F+L +  V+
Sbjct  303  TGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL  362

Query  376  ETSEPDPVETGTATAGEGVLRDSGPLDGLAKTeaieriieilaerGTGQGTINYRLRDWL  435
            E ++ +     +A + +G+  +S+ LDGL K+ AI +++E L   G G+  + YRLRDWL
Sbjct  363  EGGNVE----EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWL  418

Query  436  LSRQRYWGTPIPIIHCPSCGEVPVPDEQLPVTLPELKGAELAPKGVSPLAAATEWVNVDC  495
            +SRQRYWG PIPIIH       +VP+ +LP+ LP  K+   +  G SPLA  T+W++V  
Sbjct  419  FSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTR  478

Query  496  PSCGGPAERDTDTMDTFVDSSWYFLRYCSPRLDTAPFDTEAVEKWGPVDHYIGGKEHATL  555
               G  + R+T+TM    +SSWY+LRY  P+      D E + +W PVD Y+GG EHA L
Sbjct  479  ED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVL  537

Query  556  HLMYARFFTKVLYDMGMVSFTEPFRRLTNQGQVIN----QGRA-----------------  594
            HL+YARF  KVLYD+G+V+  EPF++L NQG ++     ++R+                 
Sbjct  538  HLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFH  597

Query  595  -------------MSKSLGNGVDLGKEIDAYGVDAVRLTMLFASPPEEdvdwadvsvvaa  641
                         MSKSL N V+ +  ++ YG D++R+  +F +P +  + W++ ++ ++
Sbjct  598  VETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGS  657

Query  642  QKFLNRAYRVMSEAGAASAPGTDPAKGDTDLRRTTHRTVDQITALVESRRFNVAIARTME  701
            +KFL+R YR+++    +   +         L +  + TV  +T  V+  +FN AIA+ M 
Sbjct  658  RKFLDRVYRLITTKEITEENS-------GALDKVYNETVKAVTEQVDQMKFNTAIAQLMV  710

Query  702  LVSAVRKAIDSGPGaadpavreaaeavavSLSLFAPYVAEEGWEKLGRSG-SVAVGNWPE  760
            +V+A  K         D    + A +    ++ FAP ++EE W+ L  SG S++   WP 
Sbjct  711  FVNAANKE--------DKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPS  762

Query  761  VDPALLVQESVTCVVQVQSKVRDKLSVAPDIDPAELERLALASEKAQGFIGDKQIRKVVV  820
             D + LV++ V  VVQ+++KV+ KL VA D+   EL+ +ALA+EK Q+ I++K+I KV+ 
Sbjct  763  YDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIA  822

Query  821  RAPKLVNIVV  830
             + KLVNIV+
Sbjct  823  VPNKLVNIVI  832

1481) A2cp1_2911 in NC_011891


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  516 bits (1946),  Expect = 3e-147, Method: Compositional matrix adjust.
 Identities = 353/861 (41%), Positives = 545/861 (64%), Gaps = 68/861 (7%)

Query  7    YEPQSIEPRWQRRWEEAGAFKAGRRPDADTRYVLEMFPYPSGA-MHMGHARVYTIGDALA  65
            Y+  +IEP+WQ  W +  +FK+G  +     Y L+MFPYPSGA +H+GH+  YT  D L+
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  66   RHLRMRGFDVLHPIGFDALGLPAENAAIKDGRHPAERTRENVVSFRAEMKRLGYSFDWER  125
            R  R +G +VLHP+G DA+GLPAE+ A+  G +PAE T EN+ +F+ +++ LG+S+DW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  126  ELVTADASYYRWNQWFFLKLLEKGIAYRRQGKVNWCTGCQTVIANEQVVDDNRCERCGSP  185
            E+ T+D++YY+W QW+F KL EKG+AY  +  VNW     T IANE+V+ D   ER G P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  186  VVEKIHPEWAFRITAYAqqlldgldglKDWPDRVTTMQRNWIGKSEGAEVDFALAAGGAA  245
            VV K   +W ++ITAYA++LL++L+ + DWP+ +  MQRNWIGKS GA+V F +   +  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  246  VKVFTTRVDTIYGCTYVVLAPEHPLVAQVTAPERRAEVDAFVARMRKTDAVERTGEGAPK  305
              VFTTR DT++G TY VLAPEH+LV  +T++++   V  +  +      + RT+ +  K
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEK  302

Query  306  EGVFTGAFAVNPFTGEQVPIWIANFVLAEYGTGAVMSVPAHDQRDFEFARKYGLPVRVVI  365
             GV TG++A+NP  G ++P+WIA++VLA YGTGA+M+VPAHD+RD EFA+++ L +  V 
Sbjct  303  TGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV-  361

Query  366  QPAQGARLPAGDALDRAATEDGVLEGSGPFTGLasaeararmsahaaeKGFGQGTVRWHL  425
                   L +G+  + A TEDG+   S+ + GL  A A A+M       G G+  V  +L
Sbjct  362  -------LEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRL  414

Query  426  RDWGFSRQRYWGTPIPIIYCDEHGMVPVPEQDLPVVLPAEAII--TGTGEPPLAKVASFV  483
            RDW FSRQRYWG PIPII  ++    +VPE +LP+VLP    I  +GTGE+PLA+V+  +
Sbjct  415  RDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWL  474

Query  484  NTTCPRCGKPARREVETMDTFVDSSWYYARYLSPRDDARPFDPEVARRWLPVDVYVGGPE  543
            + T     K +RRE +TM    +SSWYY RY+ P++  +  D E+ ++WLPVD+YVGG+E
Sbjct  475  EVTREDGVK-GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAE  533

Query  544  HAVMHLLYFRFWHRVMHELGLVHEDEPVRRLVTQGIVNGP---DGR--------------  586
            HAV+HLLY RFWH+V+ +LG+V   EP ++L  QG++ G    D+R              
Sbjct  534  HAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDG  593

Query  587  ----------------KMSKRWGNVVAPGGMVSRFGADTVRMFMLFAAPPEKDIDWSDEQ  630
                            KMSK   NVV P+++V ++GADT+R++ +F +P +  I WS+E 
Sbjct  594  SFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEG  653

Query  631  VDGLFRFLARVWRIYFARQACFDaseaalaqaagealelrrrTHRTIKRVTEGLEADLKF  690
            ++G  +FL RV R+  +++               ++  L +  + T+K VTE ++ ++KF
Sbjct  654  LEGSRKFLDRVYRLITTKEIT-----------EENSGALDKVYNETVKAVTEQVD-QMKF  701

Query  691  NTSIAALMELVNALYAFEPASEPDRaavreallalatllapfaPHVAEELWHEVMGPVAR  750
            NT+IA LM        F  A++ +     +   ++  L+APFAPH++EELW+ + ++   
Sbjct  702  NTAIAQLM-------VFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGES  754

Query  751  ERLVADAPWPPFDPALIVADTVTIAVQVNGKLRGEVQapaaageaevralaeaDEKVKVH  810
               ++  PWP++D + +V + V I VQ++GK+++ +  +   +  E++ +A A+EKV+ +
Sbjct  755  ---ISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAE  811

Query  811  LAGKTVRKVVFVPKRLVNFVV  831
            +AGK + KV+ VP++LVN+V+
Sbjct  812  IAGKDIIKVIAVPNKLVNIVI  832

1482) Snas_4914 in NC_013947


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  516 bits (1945),  Expect = 4e-147, Method: Compositional matrix adjust.
 Identities = 352/739 (48%), Positives = 490/739 (67%), Gaps = 56/739 (7%)

Query  217  DHRLAYVSEAPVNWCPGLGTVLSNEEVTAEGRSERGNFPVYTRKLKQWMMRITAYADRLL  276
            +  LAY +E PVNW   LGT ++NEEV ++G SERG +PV  + ++QWM++ITAYA+RLL
Sbjct  145  EKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLL  204

Query  277  EDLDDVDWPDSTIRLQRNWIGRSTGAHVRFGTEAG--DITVFTTRPDTLFGATYMVLAPE  334
            EDL++VDWP+S   +QRNWIG+STGA+V F       D+TVFTTRPDTLFGATY VLAPE
Sbjct  205  EDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPE  264

Query  335  HELVDTLTAATWPAGTDARWTSGEATPaeavaayrafaaaKTDVERQADAKEKTGVFIGA  394
            H LVD++T++            +EA +      Y+  A+ K+D+ R   AKEKTGV  G+
Sbjct  265  HALVDAITTS----------DQAEAVA-----DYKRQASLKSDLARTDLAKEKTGVWTGS  309

Query  395  YATNPVSGDSVPVFIADYVLAGYGTGAIMAVPGQDERDWEFAEAFGLPIIRTVQPSEGFE  454
            YA NPV+G  +PV IADYVLA+YGTGAIMAVP++DERDWEFA  F L II  ++ ++  E
Sbjct  310  YAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNV-E  368

Query  455  GKAYTGEGPAVNSPAEAVTTGAPSLNGMGVVEAKQAITEWLTASGHGEGTTTYRLRDWLF  514
              A+T +G  +NS           L+G++   A   + EWL A G G+   TYRLRDWLF
Sbjct  369  EAAFTEDGLHINS---------DFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLF  419

Query  515  SRQRYWGEPFPIVFDETGLPVALPESMLPVELPELDDFSPKTYepddadsapeppLGRAG  574
            SRQRYWGEP+PI+  E G + A+PES LP+ LP   D+ P          + E+PL+   
Sbjct  420  SRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSG--------TGESPLANVT  471

Query  575  DWVEVTLDLGDGPKKYRREVNTMPNWAGSCWYQLRYTDPFNEEALADPVNEKYWMGPNSE  634
            DW+EVT +  DG K  RRE NTMP+WAGS WY LRY DP N E LAD    K W+     
Sbjct  472  DWLEVTRE--DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWL-----  523

Query  635  TDCGGVDLYVGGSEHAVLHLLYDRFWQKVLFDLGHVSSREPFRKLIHQGMIQAYAYTDSR  694
                 VD+YVGG+EHAVLHLLY RFW+KVL+DLG V+++EPF+KL++QGMI + +Y DSR
Sbjct  524  ----PVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSR  579

Query  695  GAYVPAAEVVEEDGRFFH--DGQEVNREYGKMGKSQRNVVTPDQMCEQYGADTFRLYEMS  752
            GA V++  V   DG FFH   G+E+++  +KM+KS +NVV PD++ EQYGADT+R+YEM 
Sbjct  580  GALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMF  639

Query  753  MGPLEVSRPWETRAVVGSQRFLQRLWRNIIDEETGEVKVADVEADAETQKLLHRTIDGVH  812
            MGPL+ S +W   ++ GS++FL+R+ R I   E  E      E  +  +K+ + T+ +V 
Sbjct  640  MGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITE------ENSGALDKVYNETVKAVT  693

Query  813  ADMDALRVNTAIAKLITLNNHVVGLAEVPRSVAEAQVLMAAPFVPHVAEELWRRL-GHGE  871
             ++D ++ NTAIA+L+ + N       +    A + V + APF PH++EELW+ L + GE
Sbjct  694  EQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGE  753

Query  872  SLANADFPVADERFLVVETVTYPVQINGKVRDRVEVSAEADQDAVREAALGTEKIVAALS  931
            S++    P  DE  LV + V   VQI+GKV+ ++ V+ +  ++ ++E AL+ EK+ A ++
Sbjct  754  SISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIA  813

Query  932  GREPKKVIVVSGRMVSIVV  950
            G++  KVI V+ ++V+IV+
Sbjct  814  GKDIIKVIAVPNKLVNIVI  832


 Score =  147 bits (541),  Expect = 4e-36, Method: Compositional matrix adjust.
 Identities = 78/149 (53%), Positives = 105/149 (71%), Gaps = 11/149 (7%)

Query  23   IEPAWQDHWEERGVFNAPNPTGKLANPDDPRAGAPKLFVMDMFPYPSGAGLHVGHPFGYI  82
            IEP WQ  W +   F++   ++K           PK++ +DMFPYPSGAGLHVGHP GY 
Sbjct  9    IEPKWQAFWADNHTFKTGTDASK-----------PKFYALDMFPYPSGAGLHVGHPEGYT  57

Query  83   ATDCFARYKRMTGYNVLHPMGFDAFGLPTELYAITTGQHPAKITEDNIATYRRQLRRLGM  142
            ATD ++R+KR  G NVLHPMG DAFGLP+E YA+ TG++PA +T +NIA ++RQ+  LG 
Sbjct  58   ATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGF  117

Query  143  AYDTVRSFATSDPDYYKWTQWIFLQIFNS  171
            +YD  R   T+DP+YYKWTQWIF ++++ 
Sbjct  118  SYDWDREVNTTDPNYYKWTQWIFTKLYEK  146

1483) leuS in NC_021252


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  516 bits (1945),  Expect = 4e-147, Method: Compositional matrix adjust.
 Identities = 405/931 (44%), Positives = 584/931 (63%), Gaps = 113/931 (12%)

Query  24   IEQRWQDYWSDHGTYHAPNPVGPLADEDGEVPSDKLFVQDMFPYPSGSGLHVGHPLGFIA  83
            IE +WQ +W+D+ T+ +          + + +  K++  DMFPYPSG+GLHVGHP G+ A
Sbjct  9    IEPKWQAFWADNHTFKT----------GTDASKPKFYALDMFPYPSGAGLHVGHPEGYTA  58

Query  84   TDVFARYHRMIGRNVLHTMGFDAFGLPAEQYAVQTGQHPRKTTEENMETYLRQIRRLGLG  143
            TD+++R+ R  G+NVLH MG DA       +++ + Q +  T ++  E    +I  +   
Sbjct  59   TDILSRFKRAQGHNVLHPMGWDA-------FGLPAEQYAMDTGNDPAEFTAENIANF---  108

Query  144  HDERRRISTIDPEYYKWTQWIFLQIFNSWYDEKAGKARPIVELETEYAQDKRRTPDGRNW  203
               +R+I++++  Y    +W                 R +   + +Y           +W
Sbjct  109  ---KRQINALGFSY----DW----------------DREVNTTDPNYY----------KW  135

Query  204  CELTRAEQLAIIDTHRLVYFSEAPVNWCPGLGTVLSNEEVTADGRSERGNFPVFRRNLRQ  263
             +      ++ +    L Y +E PVNW   LGT ++NEEV +DG SERG +PV R+ +RQ
Sbjct  136  TQWI----FTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQ  191

Query  264  WMMRITAYAdrlvddldlldWPEKVKSMQRNWIGRSHGARVSFE--SGDKKIEVFTTRPD  321
            WM++ITAYA+RL++DL+ +DWPE +K MQRNWIG+S GA V+F     DK + VFTTRPD
Sbjct  192  WMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPD  251

Query  322  TLFGATYLVVAPEHPLVDELTAATWPEGVDASWTGGaatpaeaiaeyraaaSRKSELDRQ  381
            TLFGATY V+APEH+LVD +T++  +E+V                 Y+  AS KS+L R 
Sbjct  252  TLFGATYAVLAPEHALVDAITTSDQAEAVAD---------------YKRQASLKSDLART  296

Query  382  E-NKEKTGVFTGSYAVNPADGKEIPVFVADYVLMGYGTGAIMAVPGQDTRDWEFAEKFGL  440
            +  KEKTGV TGSYA+NP +GKE+PV +ADYVL +YGTGAIMAVP++D RDWEFA +F L
Sbjct  297  DLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNL  356

Query  441  EIIRTVQPTEGFGELAFTGDGPAINSGFLDGMGVDEAKKTMIGWLEENEHGRGTVQYKLR  500
            +II  ++  +   E AFT DG  INS+FLDG++   A   M+ WLE +  G   V Y+LR
Sbjct  357  DIIPVLEGGNV-EEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  501  DWLFSRQRYWGEPFPVVYDEDGHVHALPESMLPVELPEVADYSPVTFDPEDKDSTPSSPL  560
            DWLFSRQRYWGEP+P++  EDG   A+PES LP+ LP   D  P         +T  SPL
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPL  467

Query  561  ARATDWVEVELDLGEGKKTYRRDINTMPNWAGSCWYQLRYLDPTNQDVFVAPENEAYWVG  620
            A  TDW+EV  +  +G K  RR+ NTMP+WAGS WY LRY+DP N + +   E    W+ 
Sbjct  468  ANVTDWLEVTRE--DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWL-  523

Query  621  PRPAEHGVDDPGGTDLYVGGVEHAVLHLLYSRFWHKVLFDLGHVSSKEPYRKLFNQGYVQ  680
                          D+YVGG EHAVLHLLY+RFWHKVL+DLG V++KEP++KLFNQG + 
Sbjct  524  ------------PVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMIL  571

Query  681  AYAYTDARGVHVQADQVVERDGKFFFGE--EEVNQEYGKMGKSLKNVVTPDQMAADYGAD  738
            + +Y D+RG  V +D+V  RDG FF  E  EE++Q  +KM+KSLKNVV PD++  +YGAD
Sbjct  572  GTSYRDSRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGAD  631

Query  739  TFRFYEMSMGPLDVSRPWATKDVVGAQRFLQRLWRLVVNEETGELRVSTVDATDADRKQL  798
            T+R YEM MGPLD S +W+  ++ G+++FL+R+ RL+   E  E   +++D      K  
Sbjct  632  TLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALD------KVY  685

Query  799  HKAIAGVREDYAELRFNTAGAKLIELNNHVTKVYGGAEATPRelveplvlmlaplaphla  858
            + ++ +V E+  +++FNTA A+L+ + N   K     +    +    +V ++AP+APHL+
Sbjct  686  NETVKAVTEQVDQMKFNTAIAQLMVFVNAANK----EDKLFSDYAKGFVQLIAPFAPHLG  741

Query  859  eelWKRL-GHADSLVHGPFPVVDEKYLVEDSVEYPIQVNGKVRSRVTVPadagkdavqaa  917
            EELW+ L + ++S+   P P  DE  LVE+ VE  +Q++GKV++++ V+ D +++ +Q  
Sbjct  742  EELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEV  801

Query  918  aladekvaalvGDGTPRKVIVVPGRLVNIVL  948
            ALA+EKV A +++    KVI VP +LVNIV+
Sbjct  802  ALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

1484) leuS in NC_018498


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  515 bits (1944),  Expect = 4e-147, Method: Compositional matrix adjust.
 Identities = 343/848 (41%), Positives = 542/848 (64%), Gaps = 76/848 (8%)

Query  2    YNHNLIEEKWLKKWKNKDVNRFESDSNKKKYYVLDMFPYPSAAGLHLGHVRAYTITDVIS  61
            Y+H  IE KW   W +++  +  +D++K K+Y LDMFPYPS+AGLH+GH  +YT TD++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  62   RYYKAKGFNVIHPIGFDAFGLPAEQYAINSNQNPGSWTDQNINNFINQLTSFGFDYDYHL  121
            R+ +A+G NV+HP+G DAFGLPAEQYA+++ ++P+  T +NI NF  Q+ ++GF YD + 
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  122  SLKTTDPRYYKYTQWIFSELFKANLAELVDIDVNWCEQLGTVLANEEVLIDSNGNAVSER  181
             ++TTDP YYK TQWIF+ L+   LA   ++ VNW E+LGT +ANEEVL D+     SER
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGT----SER  179

Query  182  GSFPVEKRKMKQWVLKITTFADALLEGLDTLDWPEPIKEMQRNWIGKSKGVTINFQLKDH  241
            G++PV ++ M+QW+LKIT++A+ LLE+L+ +DWPE+IK+MQRNWIGKS G  + F++KD 
Sbjct  180  GGYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDT  239

Query  242  KEAIAIFTTKPQTIFGVSFLAVSTNHWLAKKIAETNKKVASFlkkqlqktttlkqkATLY  301
               +++FTT+P+T+FG ++  ++ +H L   I+ +++  A    K+     +   ++ L 
Sbjct  240  DKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA  299

Query  302  -DGIDLLTN--AIHPLTNELIPVYVANYVIEGYGTDAIMGVGAHNENDNFFARKQKLKII  358
             +  ++ T   AI+P+    +PV +A+YV+ +YGT+AIM+V AH+E D  FA++ +L II
Sbjct  300  KEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDII  359

Query  359  NVIDKKERLQNSFAYNGLT---------TKEAQVAITNE-LISQNKAKLTTVYKLRDWIF  408
             V++  +  + +F+ +GL           K + +A   E L ++  ++    Y+LRDW+F
Sbjct  360  PVLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLF  419

Query  409  SRQRYWGEPFPIIF--DENNTPHlveqlpvelplleNYKPDGSGNSPLMRNQAWVNIVKD  466
            SRQRYWGEP+PII   D  +T+    +LP+ LP+  + +P G+G+SPL     W+++ ++
Sbjct  420  SRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRE  479

Query  467  N-IHYQRETNTMPQWAGSCWYYLGYLMLIKNPNFWPIDSKEAKKLFDQYLPVDLYVGGAE  525
            + +  +RETNTMPQWAGS WYYL Y+    +P+    +      L+ Q LPVD+YVGGAE
Sbjct  480  DGVKGRRETNTMPQWAGSSWYYLRYI----DPH--NTEKLADEELLKQWLPVDIYVGGAE  533

Query  526  HAVLHLLYARFWHKFLFDKKLVSTKEPFQKLINQGMVLGPD-------------------  566
            HAVLHLLYARFWHK L+D  +V+TKEPFQKL+NQGM+LG                     
Sbjct  534  HAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDG  593

Query  567  --------------GKKMSKSKGNTINPTPLVDSHGADALRLYLMFMGPISASLTWNDEG  612
                            KMSKS  N +NP  +V+  GAD+LR+Y MFMGP+ AS++W++EG
Sbjct  594  SFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEG  653

Query  613  LNGMRRWLDRVYNFFFNHAVVTDQVSQETTFAYNLFLKNSYCHLDKHELNLVISEMMIFL  672
            L+G R+ LDRVY ++     +T++ S      YN  +K    ++D+  +N  I+++M+F+
Sbjct  654  LEGSRKFLDRVYRLITTKE-ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFV  712

Query  673  NFLYKTKKISLNYAKGFLTVLSFFAPFLAEELNEKCGLEPFVVKQAISLVDYQLFETAK-  731
            N   K  K+  +YAKGF+ +++ FAP L+EEL +  +L +    ++IS V    ++ +K 
Sbjct  713  NAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ--ALTA--SGESISYVPWPSYDESKL  768

Query  732  ----TKVILSINGKFKA----AKEFTKGSLEIDVLESFKQDKEINDILNQPIERVVYVQD  783
                  +++ I+GK KA    AK++++  L+   L +   +K   +I  + I +V+ V +
Sbjct  769  VENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALAN---EKVQAEIAGKDIIKVIAVPN  825

Query  784  RIINVLLK  791
            +++N+++K
Sbjct  826  KLVNIVIK  833

1485) leuS in NC_018496


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  515 bits (1944),  Expect = 4e-147, Method: Compositional matrix adjust.
 Identities = 343/848 (41%), Positives = 542/848 (64%), Gaps = 76/848 (8%)

Query  2    YNHNLIEEKWLKKWKNKDVNRFESDSNKKKYYVLDMFPYPSAAGLHLGHVRAYTITDVIS  61
            Y+H  IE KW   W +++  +  +D++K K+Y LDMFPYPS+AGLH+GH  +YT TD++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  62   RYYKAKGFNVIHPIGFDAFGLPAEQYAINSNQNPGSWTDQNINNFINQLTSFGFDYDYHL  121
            R+ +A+G NV+HP+G DAFGLPAEQYA+++ ++P+  T +NI NF  Q+ ++GF YD + 
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  122  SLKTTDPRYYKYTQWIFSELFKANLAELVDIDVNWCEQLGTVLANEEVLIDSNGNAVSER  181
             ++TTDP YYK TQWIF+ L+   LA   ++ VNW E+LGT +ANEEVL D+     SER
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGT----SER  179

Query  182  GSFPVEKRKMKQWVLKITTFADALLEGLDTLDWPEPIKEMQRNWIGKSKGVTINFQLKDH  241
            G++PV ++ M+QW+LKIT++A+ LLE+L+ +DWPE+IK+MQRNWIGKS G  + F++KD 
Sbjct  180  GGYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDT  239

Query  242  KEAIAIFTTKPQTIFGVSFLAVSTNHWLAKKIAETNKKVASFlkkqlqktttlkqkATLY  301
               +++FTT+P+T+FG ++  ++ +H L   I+ +++  A    K+     +   ++ L 
Sbjct  240  DKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA  299

Query  302  -DGIDLLTN--AIHPLTNELIPVYVANYVIEGYGTDAIMGVGAHNENDNFFARKQKLKII  358
             +  ++ T   AI+P+    +PV +A+YV+ +YGT+AIM+V AH+E D  FA++ +L II
Sbjct  300  KEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDII  359

Query  359  NVIDKKERLQNSFAYNGLT---------TKEAQVAITNE-LISQNKAKLTTVYKLRDWIF  408
             V++  +  + +F+ +GL           K + +A   E L ++  ++    Y+LRDW+F
Sbjct  360  PVLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLF  419

Query  409  SRQRYWGEPFPIIF--DENNTPHlveqlpvelplleNYKPDGSGNSPLMRNQAWVNIVKD  466
            SRQRYWGEP+PII   D  +T+    +LP+ LP+  + +P G+G+SPL     W+++ ++
Sbjct  420  SRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRE  479

Query  467  N-IHYQRETNTMPQWAGSCWYYLGYLMLIKNPNFWPIDSKEAKKLFDQYLPVDLYVGGAE  525
            + +  +RETNTMPQWAGS WYYL Y+    +P+    +      L+ Q LPVD+YVGGAE
Sbjct  480  DGVKGRRETNTMPQWAGSSWYYLRYI----DPH--NTEKLADEELLKQWLPVDIYVGGAE  533

Query  526  HAVLHLLYARFWHKFLFDKKLVSTKEPFQKLINQGMVLGPD-------------------  566
            HAVLHLLYARFWHK L+D  +V+TKEPFQKL+NQGM+LG                     
Sbjct  534  HAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDG  593

Query  567  --------------GKKMSKSKGNTINPTPLVDSHGADALRLYLMFMGPISASLTWNDEG  612
                            KMSKS  N +NP  +V+  GAD+LR+Y MFMGP+ AS++W++EG
Sbjct  594  SFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEG  653

Query  613  LNGMRRWLDRVYNFFFNHAVVTDQVSQETTFAYNLFLKNSYCHLDKHELNLVISEMMIFL  672
            L+G R+ LDRVY ++     +T++ S      YN  +K    ++D+  +N  I+++M+F+
Sbjct  654  LEGSRKFLDRVYRLITTKE-ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFV  712

Query  673  NFLYKTKKISLNYAKGFLTVLSFFAPFLAEELNEKCGLEPFVVKQAISLVDYQLFETAK-  731
            N   K  K+  +YAKGF+ +++ FAP L+EEL +  +L +    ++IS V    ++ +K 
Sbjct  713  NAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ--ALTA--SGESISYVPWPSYDESKL  768

Query  732  ----TKVILSINGKFKA----AKEFTKGSLEIDVLESFKQDKEINDILNQPIERVVYVQD  783
                  +++ I+GK KA    AK++++  L+   L +   +K   +I  + I +V+ V +
Sbjct  769  VENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALAN---EKVQAEIAGKDIIKVIAVPN  825

Query  784  RIINVLLK  791
            +++N+++K
Sbjct  826  KLVNIVIK  833

1486) leuS in NC_011296


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  515 bits (1943),  Expect = 5e-147, Method: Compositional matrix adjust.
 Identities = 314/672 (47%), Positives = 440/672 (66%), Gaps = 26/672 (3%)

Query  5    YDFKNIETKWQNEWLKNKLFEVNEDSSKQKFYCLEMFPYPSGR-IHMGHVRNYAIGDVIA  63
            YD   IE KWQ  W  N  F    D+SK KFY L+MFPYPSG  +H+GH   Y+  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYKRMKGLKVLHPMGWDAFGLPAENAAIKHGVHPAKWTYENIDYMKNQLIKLGLSYDWRR  123
            R+KR +G +VLHPMGWDAFGLPAE+ A+  G +PA  T ENI   K Q+  LG+SYDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVTTCSPEYYKWNQWIFLKLYERGLAYRKSSFVNWCPSCATVLANEQVI-DGACWRCETQ  182
            EV T  P+YYKW QWIF KLYE+GLAY     VNW    +T +ANE+V+ DG+  R    
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VEQKELEQWFLKITAYAEELLKDCDRLTGWPEKVLTMQRNWIGKSEGVEVDFPIEGLNEA  242
            V +K + QW LKITAYAE LL D + + +WPE +  MQRNWIGKS G +V F + + +  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LRIFTTRPDTIFGVTFMCLSPEHPLADRL--CEDKEAL---RRIRQLQRE------PEIK  291
            + +FTTRPDT+FG T+  L+PEH+L D +   ++ EA+   +R   L+ +      +  K
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEK  302

Query  292  EGIFTGKYAINPLNGERVPIWIANFVLMEYGTGAIMSVPAHDQRDFEFAVRYGIPIKVVI  351
             G+ TG YAINP+NG  +P+WIA++VL  YGTGAIM+VPAHD+RD EFA ++ + I  V+
Sbjct  303  TGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL  362

Query  352  KPKDSELSEPLNEAFEDEGVMVNSGEFSGLPSSEGKKAVADYIEKKGLGKKTINYRLRDW  411
               + E     + AF ++G+ +NS+ + GL  + +   + + +E  G+G+  + YRLRDW
Sbjct  363  EGGNVE-----EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDW  417

Query  412  GISRQRYWGTPIPIIYCEKCGIVPVPEKDLPVILP--ENISLTGKGESPLKYVEEFYKTK  469
             +SRQRYWG PIPII  E     +VPE +LP++LP   +I  +G GESPL  V +     
Sbjct  418  LFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT  477

Query  470  CPRCGKEARRETDTMDTFVDSSWYFVRYCSLQNEDAFHKEK-IKYWMPVDQYIGGIEHAV  528
                 K +RRET+TM    +SSWY++RY   +N + +  E  +K W+PVD Y+GG EHAV
Sbjct  478  REDGVK-GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  529  LHLLYARFFTKVLRDIGIVPFDEPFERLLTQGMVCMESYRCPEHDYLFPKEV--KDGKCI  586
            LHLLYARF  KVL D+G+VP  EPF++L+ QGM+   SYR +    +    V  +DG  +
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFF  596

Query  587  HCGSSVTVGRV-EKMSKSKKNIIDPDEMIEQYGTDTVRVFTLFAAPPEKDLEWSSQGVEG  645
            H  ++  + +   KMSKS KN+++PD+++EQYG+DT+RV+ +F +P +  + WS +G+EG
Sbjct  597  HVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEG  656

Query  646  AHRFLKRVYALI  657
            +++FL RVY LI
Sbjct  657  SRKFLDRVYRLI  668


 Score =  103 bits (372),  Expect = 7e-23, Method: Compositional matrix adjust.
 Identities = 67/155 (44%), Positives = 112/155 (73%), Gaps = 9/155 (5%)

Query  713  HRTIKRVTLDIEKEYQFNTAIARLMEFVNEVYGYEPKTEEERKVFKFAIRNFLILLSPFA  772
            + T+K VT +++ + +FNTAIA+LM FVN        ++ E K+F    + F+ L++PFA
Sbjct  686  NETVKAVTEQVD-QMKFNTAIAQLMVFVNA-------ANKEDKLFSDYAKGFVQLIAPFA  737

Query  773  PHIAEELWREIGEEGFILN-EPWPTYDEALAREQMIELVVQINGKVRSKIMIPQGMSDEE  831
            PH++EELW+ +   G  ++  PWP+YDE+   E+ +E+VVQI+GKV++K+++++++S EE
Sbjct  738  PHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREE  797

Query  832  IVKIALDDEKVKQWVNGKEILKVIPVKGKLVNIVV  866
            +  +AL +EKV+  + GK+I+KVI+V  KLVNIV+
Sbjct  798  LQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

1487) Cfla_2234 in NC_014151


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  515 bits (1943),  Expect = 6e-147, Method: Compositional matrix adjust.
 Identities = 341/736 (47%), Positives = 489/736 (67%), Gaps = 52/736 (7%)

Query  247  RRLAYLSQTPVNWAPGLGTVLANEEVTADGRSERGNFPVFQRSLRQWNMRITAYADRLTD  306
            + LAY ++ PVNW   LGT +ANEEV +DG SERG +PV ++++RQW ++ITAYA+RL +
Sbjct  146  KGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLE  205

Query  307  DLDRIDWPEKVKAMQRHWIGRSTGARVRFAVQGGE-QLEVFTTRPDTLFGATFLVVSPEH  365
            DL+ +DWPE +K MQR+WIG+STGA V F V++ + ++ VFTTRPDTLFGAT+ V++PEH
Sbjct  206  DLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEH  265

Query  366  PLLDEVPAQWPDGTSSAWTGGHSSPTDAVADYRREAAAKTALERQQDAGRKTGVFTGHLA  425
            +L+D + +              S  ++AVADY+R+A+ K+ L R + A  KTGV TG  A
Sbjct  266  ALVDAITT--------------SDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYA  311

Query  426  TNPVNGELLPVFTADYVLMGYGTGAIMAVPGGDERDFQFAQAFGLPVVYTVDAPEGTAPG  485
             NPVNG  +PV  ADYVL +YGTGAIMAVP+ DERD +FA+ F L ++  +++ +    +
Sbjct  312  INPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGN-VEEA  370

Query  486  ARTGDGAIINSANDEVSLDGLDVPTAKERIVAWLEEHGVGERTITYRLRDWLFSRQRYWG  545
            A T DG  INS      LDGLD ++A  ++V WLE +GVG+  +TYRLRDWLFSRQRYWG
Sbjct  371  AFTEDGLHINSD----FLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWG  426

Query  546  EPFPVVYDEDDTPIALPASALPVELPEVPDFSPRTYDPDDATSEPEPPLGRNTDWLYVEL  605
            EP+P++  ED+T+ A+P S LP+ LP   D+ P        ++  E+PL+  TDWL  E+
Sbjct  427  EPIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTDWL--EV  476

Query  606  DLGDGPRRYRRDANTMPNWAGSCWYHLRYLDPRSDDALVDPALEDYWMGPGHGTQAEGST  665
               DG +  RR++NTMP+WAGS WY LRY+DP++ + L D  L   W+            
Sbjct  477  TREDGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWL------------  523

Query  666  GGVDLYVGGVEHAVLHLLYARFWHKVLYDLGHVRSAEPFHKLFNQGYIQGYAYTDERGVY  725
              VD+YVGG EHAVLHLLYARFWHKVLYDLG V + EPF+KLFNQG I G +Y D RG  
Sbjct  524  -PVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGAL  582

Query  726  VPAAEVVEDEASPTGFRWNGEPVHREYGKIGKSLKNAVSPDEMYEAYGADTLRVYEMSMG  785
            V++  V   ++S       GE +++  +K++KSLKN V+PD++ E YGADTLRVYEM MG
Sbjct  583  VATDKVEKRDGSFFHVE-TGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMG  641

Query  786  PLDLSRPWETRAVVGAQRFLQRLWRNVVDETTGELVVTEDAPSTETLRVLHRTIEGVRED  845
            PLD S +W   ++ G+++FL+R+ R +         +TE+ +++   +V + T+ +V E+
Sbjct  642  PLDASIAWSEEGLEGSRKFLDRVYRLITTKE-----ITEENSGALD-KVYNETVKAVTEQ  695

Query  846  MEGMRINTAIAKLIVLNNHVTTLERAPRSVVEALVVMTAPVAPHIAEELWARL-GHERSV  904
            ++ M++NTAIA+L+V+ N     ++       ++V + AP APH++EELW  L +   S+
Sbjct  696  VDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESI  755

Query  905  VHATFPQADPQHLVEETVTCVFQVQGKVRGRAEVAPSAGEDELRELALADAGVQRALAGR  964
                 P  D   LVE+ V  V Q++GKV+++  VA   + +EL+E+ALA+  VQ  +AG+
Sbjct  756  SYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGK  815

Query  965  DVRTVIVRAPRLVNVV  980
            D+  VI  + +LVN+V
Sbjct  816  DIIKVIAVPNKLVNIV  831


 Score =  124 bits (452),  Expect = 4e-29, Method: Compositional matrix adjust.
 Identities = 72/152 (48%), Positives = 100/152 (66%), Gaps = 15/152 (9%)

Query  36   IELRWQDEWEKRGTYFTPNPVGELTDGEGRHADPAARP-FFVMDMFPYPSGAGLHVGHPL  94
            IE +WQ  W    T+              + +  A++P F+ +DMFPYPSGAGLHVGHP 
Sbjct  9    IEPKWQAFWADNHTF--------------KTGTDASKPKFYALDMFPYPSGAGLHVGHPE  54

Query  95   GYIATDVVGRFRRMCGDNVLHALAFDAFGLPAEQYAVQTGRHPRVTTEANIEIMQRQLRR  154
            GY ATD+++RF+R  G+NVLH+++ DAFGLPAEQYA++TG +P   T  NI   +RQ+  
Sbjct  55   GYTATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINA  114

Query  155  LGLAHDPRRSFATIDPDYVRWTQWIFLQIFES  186
            LG++ D  R   T DP+Y +WTQWIF +++E 
Sbjct  115  LGFSYDWDREVNTTDPNYYKWTQWIFTKLYEK  146

1488) leuS in NC_012526


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  515 bits (1941),  Expect = 7e-147, Method: Compositional matrix adjust.
 Identities = 358/850 (43%), Positives = 514/850 (61%), Gaps = 62/850 (7%)

Query  21   YNPHAIEQKWQDHWEKSGIYTFDEHGPGEKHYALTMFPYPSG-NLHIGHWYANVAPDARA  79
            Y+  AIE KWQ  W  +  +  + +++  K YAL MFPYPSG  LH+GH  +  A D  +
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  80   RWMRMRGYNVLFPMGFDAFGLPAENAAIKNNLDPAKWTYSNIEHMTGQFRRMGTMIDWSR  139
            R  R +G NVL PMG DAFGLPAE+ A+    DPA  T  NI +   Q+  +G   DW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  140  KFATCDPEYYRWNQWFFTEFFRRGLAYKKDGLVNWCPKDQTVLANEQVV-NGHCERCGTA  198
               T DP+YY+W QW+FT ++ +GLAY  +  VNW     T +ANE+V+ +G  ER G +
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  199  VERRNLSQWYLKITDYADELL-DFGSADMPERVRLMQTNWIGKSVGAEVTFETPAGPE--  255
            V R+ + QW LKIT YA+ LL D+   D PE ++ MQ NWIGKS GA+VTF         
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  256  TVFTTRPDTLMGATFLVLAPEHAKVTTLTTDEQRSEVEAYVEAAGRKTDVERQQDSGDKT  315
            TVFTTRPDTL GAT+ VLAPEHA V ++TT +Q   V  Y   A+ K+D+ R + + +KT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  316  GVFTGSFATHPITGHQLPIWVADYVLVTYGTGSIMAVPAHDERDFAFARKFGLEIREVIR  375
            GV TGS+A +P+ G ++P+W+ADYVL +YGTG+IMAVPAHDERD  FA++F L+I  V+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  376  AEGAEAMDPQTAETSYSGEGLIVNSGEFDGMPGGKASIATVVEKLEARGVARARTTYRLR  435
            +   E       E++++ +GL +NS+ +DG+  + ++IA +VE LEA GV+    TYRLR
Sbjct  364  GGNVE-------EAAFTEDGLHINSDFLDGLDKA-SAIAKMVEWLEAEGVGNENVTYRLR  415

Query  436  DWLVSRQRYWGTPIPIVYCAEHGAQPVPAEELPVRLPESVEFTP--TGQSPLKLNRDWVQ  493
            DWL SRQRYWG PIPI+   +  + +VP  ELP+ LP + ++ P  TG+SPL    DW++
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  494  TTCPVCGGPAERDTDTMDTFVDSSWYMYRYLSPHSEGHPFDPA-HAHLLPVDLYTGGIEH  552
             T    G  + R+T+TM    +SSWY  RY+ PH+     D     + LPVD+Y GG EH
Sbjct  476  VTRE-DGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEH  534

Query  553  AILHLLYSRFWTKVMRDMGLTTQSEPFARLRNQGMILG----------------------  590
            A+LHLLY+RFW KV+ D+G+    EPF +L NQGMILG                      
Sbjct  535  AVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGS  594

Query  591  -----------EDNEKMSKSRGNVVDPDDLVREYGADTVRTFLMFIAPWELGGPWDSQGI  639
                       +   KMSKS  NVV+PDD+V +YGADT+R + MF++P + + +W  +G+
Sbjct  595  FFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGL  654

Query  640  NGPAKWLSRVWNLYFEDKTTGPEENITEADLRHAVHSALAKVNGDFERMSFNTIIATLME  699
            +G+ K L RV  L +  K    E++   + L    + ++  V  + ++M FNT IA LM 
Sbjct  655  EGSRKFLDRVYRL-ITTKEITEENS---GALDKVYNETVKAVTEQVDQMKFNTAIAQLMV  710

Query  700  LTNILVKAKRSPVASTAAWDEALGIFNLMLAPIAPHIAEEIWAGRNQEGSVHTHV-WPAV  758
            + N   K  +     + +       F  ++AP+APH++EE+W +    G   + V WP+ 
Sbjct  711  FVNAANKEDKLFSDYAKG-------FVQLIAPFAPHLGEELWQALTASGESISYVPWPSY  763

Query  759  DEAAAVRDTVTIGVQVSGKVRGEVSISKTATQDQALEAARTNADVARFIEGKQVVKEIYV  818
            DE+  V + V I VQ+ GKV++ + ++K  ++++  E A +N  V   I GK+++K I V
Sbjct  764  DESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAV  823

Query  819  PGRIINIVVK  828
            P +++NIV+K
Sbjct  824  PNKLVNIVIK  833

1489) leuS in NC_012803


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  515 bits (1941),  Expect = 7e-147, Method: Compositional matrix adjust.
 Identities = 354/854 (42%), Positives = 530/854 (63%), Gaps = 63/854 (7%)

Query  21   YSFRDVEARWAGYWEQAGTFAPREDGSETR-TVVDMFPYPSG-DLHMGHAEAFAMGDVVA  78
            Y    +E++W ++W +  TF    D+S  +   +DMFPYPSG +LH+GH+E+++  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  79   RHWMQRGFDVLHPIGWDSFGLPAENAAIKRDAHPAEWTYANIETQKRSFQRYGIAVDWSR  138
            R    +G +VLHP+GWD+FGLPAE+ A+  + +PAE T  NI   KR ++  G++ DW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  139  ELHTSDPEYYRWTQWLFQQLYRKGLAYRKDSPVNWCPQDQTVLANEQVV-DGRCERCGTE  197
            E++T+DP+YY+WTQW+F +LY KGLAY  + PVNW  +  T +ANE+V+ DG  ER G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  198  VTKRTLNQWYFRITEYADALLDDMDQLTGHWPERVLAMQRNWIGRSEGAHVDFQVED-GP  256
            V ++ + QW ++IT YA+ LL+D++++  +WPE +  MQRNWIG+S GA+V F+V D + 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV--DWPESIKDMQRNWIGKSTGANVTFKVKDTDK  241

Query  257  VVTVFTTRPDTLYGATFMVVaadaplaaelagddVRAELEAYREDLKKVSDIDRQATDRP  316
              TVFTTRPDTL+GAT+ V+A++ +L   ++  D    +  Y+ +    SD+ R    + 
Sbjct  242  DFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKE  301

Query  317  KSGVFLGRHAVNPLTGERLPIWASDYVLADYGTGAIMAVPAHDQRDLDFARAMGLPVRTV  376
            K+GV  G  A+NP+ G  +P+W +DYVLA YGTGAIMAVPAHD+RD +FA+   L +  V
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  377  LDTGEEDPAVSGVATTGEGILVNSGELDGLDKTaaiaraieimeerGTGRATTTYRLRDW  436
            L+ G+    V   A T +G+ +NS+ LDGLDK++AIA+ +E +E  G G    TYRLRDW
Sbjct  362  LEGGN----VEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDW  417

Query  437  LLSRQRFWGTPIPVVHCPDCGEVLVPEDQLPVTLPTDLKGEQLAPKGRSPLAAATSWVEV  496
            L+SRQR+WG PIP++H  D     VPE +LP+ LP   K+ + +  G SPLA  T W+EV
Sbjct  418  LFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVT-KDIRPSGTGESPLANVTDWLEV  476

Query  497  DCPQCGGPARRDTDTMDTFVDSSWYVLRYASPNDDARVFDPEALRRWLPVDQYVGGVEHA  556
               + G  +RR+T+TM    +SSWY LRY  P++  ++ D E L++WLPVD YVGG EHA
Sbjct  477  -TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  557  ILHLLYARFFTKALHDLGLVPFTEPFRSLLNQGQVLNGG---------------------  595
            +LHLLYARF  K L DLG+VP  EPF+ L+NQG +L  +                     
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSF  595

Query  596  -------------KAMSKSLGNGVDLGDQLDEFGVDAVRLTMVFASPPEDDVDWADVAPG  642
                           MSKSL N V+ +D ++++G D++R+  +F +P +  + W++ +  
Sbjct  596  FHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLE  655

Query  643  AAGKFLARAWRLARDVRatgapagadpadgavaLRRVTHRTVHEAQQLLDDGKFNVVVAK  702
            ++ KFL R  RL          +     + + AL +V + TV    + +D+ KFN  +A+
Sbjct  656  GSRKFLDRVYRLI--------TTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQ  707

Query  703  TMELVNAARKEIDAGAGaadpavreaveavavllslvaPYTAEDMW-VLLGHEPSVVRAG  761
             M +VNAA KE        D    +   +   L++  AP  +E++W  L +   S+    
Sbjct  708  LMVFVNAANKE--------DKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVP  759

Query  762  WPAVDESLLVEDTVTAVVQVKGKVRDTLEVPADITAEDLEARARASQKVRNFIGDAQIVK  821
            WP+ DES LVE+ V  VVQ+KGKV+  L V+ D++ E+L+  A A++KV+  I++ +I+K
Sbjct  760  WPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIK  819

Query  822  VIVREPKLVNLVIR  835
            VI    KLVN+VI+
Sbjct  820  VIAVPNKLVNIVIK  833

1490) leuS in NC_022116


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  514 bits (1939),  Expect = 1e-146, Method: Compositional matrix adjust.
 Identities = 367/742 (50%), Positives = 501/742 (68%), Gaps = 64/742 (8%)

Query  215  DHRLVYISEAPVNWCPGLGTVLSNEEVTADGRSERGNFPVFRRNLRQWMMRITAYAdrlv  274
            +  L Y +E PVNW   LGT ++NEEV +DG SERG +PV R+ +RQWM++ITAYA+RL+
Sbjct  145  EKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLL  204

Query  275  ddldlldWPEKVKSMQRNWIGRSHGARVTFKT--GDDAIEVFTTRPDTLFGATYMVLAPE  332
            +DL+ +DWPE +K MQRNWIG+S GA VTFK    D  + VFTTRPDTLFGATY VLAPE
Sbjct  205  EDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPE  264

Query  333  HPLVDKLTTAAWPDGVDERWTGGAATPAEAIKEYRVAASRKSELDRQE-NKEKTGVFTGA  391
            H+LVD +TT+                 AEA+ +Y+  AS KS+L R +  KEKTGV TG+
Sbjct  265  HALVDAITTSD---------------QAEAVADYKRQASLKSDLARTDLAKEKTGVWTGS  309

Query  392  YATNPVNDKQIPIFVADYVLMGYGTGAIMAVPGQDVRDWEFAEKFGLEIIRTVQPSEGFD  451
            YA NPVN+K++P+ +ADYVL +YGTGAIMAVP++D RDWEFA +F L+II  ++ ++  +
Sbjct  310  YAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNV-E  368

Query  452  GKAYTGDGPAINSSFLDGMDVAEAKKTIIDWLAEKGAGTGTVQYKLRDWLFSRQRYWGEP  511
              A+T DG  INS FLDG+D A A   +++WL   G G   V Y+LRDWLFSRQRYWGEP
Sbjct  369  EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEP  428

Query  512  FPVVYDEDGEVHAVPESMLPIELPEVADYSPVTFDPEDRDSMPSSPLARATDWVEVELDL  571
            +P++  EDG   AVPES LP+ LP   D  P         +   SPLA  TDW+EV  + 
Sbjct  429  IPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTDWLEVTRE-  479

Query  572  GDGPKTYRRDINTMPNWAGSCWYQLRYVDPTNSETFCAPENEQYWMGPRPGEYGADDTGG  631
             DG K  RR+ NTMP+WAGS WY LRY+DP N+E +   E  + W+              
Sbjct  480  -DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWL-------------P  524

Query  632  VDLYVGGVEHAVLHLLYSRFWHKVLFDLGHVTSKEPYRKLFNQGYIEAYAYTDARGVYVP  691
            VD+YVGG EHAVLHLLY+RFWHKVL+DLG V +KEP++KLFNQG I + +Y D+RG  V+
Sbjct  525  VDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVA  584

Query  692  AEQVEERDGKHFFN---GEEVTQEYGKMGKSLKNVVTPDEMAENYGADTFRFYEMAMGPL  748
            +++VE RDG  FF+   GEE+ Q  +KM+KSLKNVV PD++ E+YGADT+R YEM MGPL
Sbjct  585  TDKVEKRDGS-FFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPL  643

Query  749  AMSRPWATKDVVGAHRFLQRLWRLVVDESTGELRVSTEDASEADRKVLHKTIAGVREDYA  808
              S +W+  ++ G+++FL+R+ RL+        +  TE+ S A  KV + T+ +V E+  
Sbjct  644  DASIAWSEEGLEGSRKFLDRVYRLITT------KEITEENSGALDKVYNETVKAVTEQVD  697

Query  809  EMRFNTAGAKL---IELNNHVTKVYGGATSTPRelaeplvlmlaplaphlaeelWHRL-G  864
            +M+FNTA A+L   ++  N   K++++ +         +V ++AP+APHL+EELW+ L +
Sbjct  698  QMKFNTAIAQLMVFVNAANKEDKLFSDYAKG-------FVQLIAPFAPHLGEELWQALTA  750

Query  865  HVDSLVQGPFPVVDEKYLVEDSVEYPIQVNGKVRSRVTVAASASTDEVQAAALADEKVAA  924
              +S+   P P  DE  LVE+ VE  +Q++GKV++++ VA   S +E+Q  ALA+EKV A
Sbjct  751  SGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQA  810

Query  925  MVGDGSPRKVIVVPGRLVNIVL  946
             +++    KVI VP +LVNIV+
Sbjct  811  EIAGKDIIKVIAVPNKLVNIVI  832


 Score =  134 bits (493),  Expect = 2e-32, Method: Compositional matrix adjust.
 Identities = 74/148 (50%), Positives = 103/148 (70%), Gaps = 10/148 (6%)

Query  22   IEQRWQDHWADQGTFHAPNPVGPLAVEGQPVPSDKLFVQDMFPYPSGSGLHVGHPLGFIS  81
            IE +WQ  WAD+ TF +          G   +  K++  DMFPYPSG+GLHVGHP G+ +
Sbjct  9    IEPKWQAFWADNHTFKT----------GTDASKPKFYALDMFPYPSGAGLHVGHPEGYTA  58

Query  82   TDVFARYHRMIGRNVLHTMGFDAFGLPAEQYAVQTGQHPRKTTEENIRTYLRQIRRLGLG  141
            TD+++R+ R  G+NVLH MG DAFGLPAEQYA++TG++P   T ENI  + RQI  LG++
Sbjct  59   TDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFS  118

Query  142  HDERRRISTIDPEYYRWTQWIFLQIFNS  169
             D  R ++T DP+YY+WTQWIF ++++ 
Sbjct  119  YDWDREVNTTDPNYYKWTQWIFTKLYEK  146

1491) leuS in NC_017186


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  514 bits (1939),  Expect = 1e-146, Method: Compositional matrix adjust.
 Identities = 367/742 (50%), Positives = 501/742 (68%), Gaps = 64/742 (8%)

Query  215  DHRLVYISEAPVNWCPGLGTVLSNEEVTADGRSERGNFPVFRRNLRQWMMRITAYAdrlv  274
            +  L Y +E PVNW   LGT ++NEEV +DG SERG +PV R+ +RQWM++ITAYA+RL+
Sbjct  145  EKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLL  204

Query  275  ddldlldWPEKVKSMQRNWIGRSHGARVTFKT--GDDAIEVFTTRPDTLFGATYMVLAPE  332
            +DL+ +DWPE +K MQRNWIG+S GA VTFK    D  + VFTTRPDTLFGATY VLAPE
Sbjct  205  EDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPE  264

Query  333  HPLVDKLTTAAWPDGVDERWTGGAATPAEAIKEYRVAASRKSELDRQE-NKEKTGVFTGA  391
            H+LVD +TT+                 AEA+ +Y+  AS KS+L R +  KEKTGV TG+
Sbjct  265  HALVDAITTSD---------------QAEAVADYKRQASLKSDLARTDLAKEKTGVWTGS  309

Query  392  YATNPVNDKQIPIFVADYVLMGYGTGAIMAVPGQDVRDWEFAEKFGLEIIRTVQPSEGFD  451
            YA NPVN+K++P+ +ADYVL +YGTGAIMAVP++D RDWEFA +F L+II  ++ ++  +
Sbjct  310  YAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNV-E  368

Query  452  GKAYTGDGPAINSSFLDGMDVAEAKKTIIDWLAEKGAGTGTVQYKLRDWLFSRQRYWGEP  511
              A+T DG  INS FLDG+D A A   +++WL   G G   V Y+LRDWLFSRQRYWGEP
Sbjct  369  EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEP  428

Query  512  FPVVYDEDGEVHAVPESMLPIELPEVADYSPVTFDPEDRDSMPSSPLARATDWVEVELDL  571
            +P++  EDG   AVPES LP+ LP   D  P         +   SPLA  TDW+EV  + 
Sbjct  429  IPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTDWLEVTRE-  479

Query  572  GDGPKTYRRDINTMPNWAGSCWYQLRYVDPTNSETFCAPENEQYWMGPRPGEYGADDTGG  631
             DG K  RR+ NTMP+WAGS WY LRY+DP N+E +   E  + W+              
Sbjct  480  -DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWL-------------P  524

Query  632  VDLYVGGVEHAVLHLLYSRFWHKVLFDLGHVTSKEPYRKLFNQGYIEAYAYTDARGVYVP  691
            VD+YVGG EHAVLHLLY+RFWHKVL+DLG V +KEP++KLFNQG I + +Y D+RG  V+
Sbjct  525  VDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVA  584

Query  692  AEQVEERDGKHFFN---GEEVTQEYGKMGKSLKNVVTPDEMAENYGADTFRFYEMAMGPL  748
            +++VE RDG  FF+   GEE+ Q  +KM+KSLKNVV PD++ E+YGADT+R YEM MGPL
Sbjct  585  TDKVEKRDGS-FFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPL  643

Query  749  AMSRPWATKDVVGAHRFLQRLWRLVVDESTGELRVSTEDASEADRKVLHKTIAGVREDYA  808
              S +W+  ++ G+++FL+R+ RL+        +  TE+ S A  KV + T+ +V E+  
Sbjct  644  DASIAWSEEGLEGSRKFLDRVYRLITT------KEITEENSGALDKVYNETVKAVTEQVD  697

Query  809  EMRFNTAGAKL---IELNNHVTKVYGGATSTPRelaeplvlmlaplaphlaeelWHRL-G  864
            +M+FNTA A+L   ++  N   K++++ +         +V ++AP+APHL+EELW+ L +
Sbjct  698  QMKFNTAIAQLMVFVNAANKEDKLFSDYAKG-------FVQLIAPFAPHLGEELWQALTA  750

Query  865  HVDSLVQGPFPVVDEKYLVEDSVEYPIQVNGKVRSRVTVAASASTDEVQAAALADEKVAA  924
              +S+   P P  DE  LVE+ VE  +Q++GKV++++ VA   S +E+Q  ALA+EKV A
Sbjct  751  SGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQA  810

Query  925  MVGDGSPRKVIVVPGRLVNIVL  946
             +++    KVI VP +LVNIV+
Sbjct  811  EIAGKDIIKVIAVPNKLVNIVI  832


 Score =  134 bits (493),  Expect = 2e-32, Method: Compositional matrix adjust.
 Identities = 74/148 (50%), Positives = 103/148 (70%), Gaps = 10/148 (6%)

Query  22   IEQRWQDHWADQGTFHAPNPVGPLAVEGQPVPSDKLFVQDMFPYPSGSGLHVGHPLGFIS  81
            IE +WQ  WAD+ TF +          G   +  K++  DMFPYPSG+GLHVGHP G+ +
Sbjct  9    IEPKWQAFWADNHTFKT----------GTDASKPKFYALDMFPYPSGAGLHVGHPEGYTA  58

Query  82   TDVFARYHRMIGRNVLHTMGFDAFGLPAEQYAVQTGQHPRKTTEENIRTYLRQIRRLGLG  141
            TD+++R+ R  G+NVLH MG DAFGLPAEQYA++TG++P   T ENI  + RQI  LG++
Sbjct  59   TDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFS  118

Query  142  HDERRRISTIDPEYYRWTQWIFLQIFNS  169
             D  R ++T DP+YY+WTQWIF ++++ 
Sbjct  119  YDWDREVNTTDPNYYKWTQWIFTKLYEK  146

1492) leuS in NC_018266


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  514 bits (1939),  Expect = 1e-146, Method: Compositional matrix adjust.
 Identities = 367/742 (50%), Positives = 501/742 (68%), Gaps = 64/742 (8%)

Query  215  DHRLVYISEAPVNWCPGLGTVLSNEEVTADGRSERGNFPVFRRNLRQWMMRITAYAdrlv  274
            +  L Y +E PVNW   LGT ++NEEV +DG SERG +PV R+ +RQWM++ITAYA+RL+
Sbjct  145  EKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLL  204

Query  275  ddldlldWPEKVKSMQRNWIGRSHGARVTFKT--GDDAIEVFTTRPDTLFGATYMVLAPE  332
            +DL+ +DWPE +K MQRNWIG+S GA VTFK    D  + VFTTRPDTLFGATY VLAPE
Sbjct  205  EDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPE  264

Query  333  HPLVDKLTTAAWPDGVDERWTGGAATPAEAIKEYRVAASRKSELDRQE-NKEKTGVFTGA  391
            H+LVD +TT+                 AEA+ +Y+  AS KS+L R +  KEKTGV TG+
Sbjct  265  HALVDAITTSD---------------QAEAVADYKRQASLKSDLARTDLAKEKTGVWTGS  309

Query  392  YATNPVNDKQIPIFVADYVLMGYGTGAIMAVPGQDVRDWEFAEKFGLEIIRTVQPSEGFD  451
            YA NPVN+K++P+ +ADYVL +YGTGAIMAVP++D RDWEFA +F L+II  ++ ++  +
Sbjct  310  YAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNV-E  368

Query  452  GKAYTGDGPAINSSFLDGMDVAEAKKTIIDWLAEKGAGTGTVQYKLRDWLFSRQRYWGEP  511
              A+T DG  INS FLDG+D A A   +++WL   G G   V Y+LRDWLFSRQRYWGEP
Sbjct  369  EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEP  428

Query  512  FPVVYDEDGEVHAVPESMLPIELPEVADYSPVTFDPEDRDSMPSSPLARATDWVEVELDL  571
            +P++  EDG   AVPES LP+ LP   D  P         +   SPLA  TDW+EV  + 
Sbjct  429  IPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTDWLEVTRE-  479

Query  572  GDGPKTYRRDINTMPNWAGSCWYQLRYVDPTNSETFCAPENEQYWMGPRPGEYGADDTGG  631
             DG K  RR+ NTMP+WAGS WY LRY+DP N+E +   E  + W+              
Sbjct  480  -DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWL-------------P  524

Query  632  VDLYVGGVEHAVLHLLYSRFWHKVLFDLGHVTSKEPYRKLFNQGYIEAYAYTDARGVYVP  691
            VD+YVGG EHAVLHLLY+RFWHKVL+DLG V +KEP++KLFNQG I + +Y D+RG  V+
Sbjct  525  VDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVA  584

Query  692  AEQVEERDGKHFFN---GEEVTQEYGKMGKSLKNVVTPDEMAENYGADTFRFYEMAMGPL  748
            +++VE RDG  FF+   GEE+ Q  +KM+KSLKNVV PD++ E+YGADT+R YEM MGPL
Sbjct  585  TDKVEKRDGS-FFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPL  643

Query  749  AMSRPWATKDVVGAHRFLQRLWRLVVDESTGELRVSTEDASEADRKVLHKTIAGVREDYA  808
              S +W+  ++ G+++FL+R+ RL+        +  TE+ S A  KV + T+ +V E+  
Sbjct  644  DASIAWSEEGLEGSRKFLDRVYRLITT------KEITEENSGALDKVYNETVKAVTEQVD  697

Query  809  EMRFNTAGAKL---IELNNHVTKVYGGATSTPRelaeplvlmlaplaphlaeelWHRL-G  864
            +M+FNTA A+L   ++  N   K++++ +         +V ++AP+APHL+EELW+ L +
Sbjct  698  QMKFNTAIAQLMVFVNAANKEDKLFSDYAKG-------FVQLIAPFAPHLGEELWQALTA  750

Query  865  HVDSLVQGPFPVVDEKYLVEDSVEYPIQVNGKVRSRVTVAASASTDEVQAAALADEKVAA  924
              +S+   P P  DE  LVE+ VE  +Q++GKV++++ VA   S +E+Q  ALA+EKV A
Sbjct  751  SGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQA  810

Query  925  MVGDGSPRKVIVVPGRLVNIVL  946
             +++    KVI VP +LVNIV+
Sbjct  811  EIAGKDIIKVIAVPNKLVNIVI  832


 Score =  134 bits (493),  Expect = 2e-32, Method: Compositional matrix adjust.
 Identities = 74/148 (50%), Positives = 103/148 (70%), Gaps = 10/148 (6%)

Query  22   IEQRWQDHWADQGTFHAPNPVGPLAVEGQPVPSDKLFVQDMFPYPSGSGLHVGHPLGFIS  81
            IE +WQ  WAD+ TF +          G   +  K++  DMFPYPSG+GLHVGHP G+ +
Sbjct  9    IEPKWQAFWADNHTFKT----------GTDASKPKFYALDMFPYPSGAGLHVGHPEGYTA  58

Query  82   TDVFARYHRMIGRNVLHTMGFDAFGLPAEQYAVQTGQHPRKTTEENIRTYLRQIRRLGLG  141
            TD+++R+ R  G+NVLH MG DAFGLPAEQYA++TG++P   T ENI  + RQI  LG++
Sbjct  59   TDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFS  118

Query  142  HDERRRISTIDPEYYRWTQWIFLQIFNS  169
             D  R ++T DP+YY+WTQWIF ++++ 
Sbjct  119  YDWDREVNTTDPNYYKWTQWIFTKLYEK  146

1493) leuS in NC_014318


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  514 bits (1939),  Expect = 1e-146, Method: Compositional matrix adjust.
 Identities = 367/742 (50%), Positives = 501/742 (68%), Gaps = 64/742 (8%)

Query  215  DHRLVYISEAPVNWCPGLGTVLSNEEVTADGRSERGNFPVFRRNLRQWMMRITAYAdrlv  274
            +  L Y +E PVNW   LGT ++NEEV +DG SERG +PV R+ +RQWM++ITAYA+RL+
Sbjct  145  EKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLL  204

Query  275  ddldlldWPEKVKSMQRNWIGRSHGARVTFKT--GDDAIEVFTTRPDTLFGATYMVLAPE  332
            +DL+ +DWPE +K MQRNWIG+S GA VTFK    D  + VFTTRPDTLFGATY VLAPE
Sbjct  205  EDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPE  264

Query  333  HPLVDKLTTAAWPDGVDERWTGGAATPAEAIKEYRVAASRKSELDRQE-NKEKTGVFTGA  391
            H+LVD +TT+                 AEA+ +Y+  AS KS+L R +  KEKTGV TG+
Sbjct  265  HALVDAITTSD---------------QAEAVADYKRQASLKSDLARTDLAKEKTGVWTGS  309

Query  392  YATNPVNDKQIPIFVADYVLMGYGTGAIMAVPGQDVRDWEFAEKFGLEIIRTVQPSEGFD  451
            YA NPVN+K++P+ +ADYVL +YGTGAIMAVP++D RDWEFA +F L+II  ++ ++  +
Sbjct  310  YAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNV-E  368

Query  452  GKAYTGDGPAINSSFLDGMDVAEAKKTIIDWLAEKGAGTGTVQYKLRDWLFSRQRYWGEP  511
              A+T DG  INS FLDG+D A A   +++WL   G G   V Y+LRDWLFSRQRYWGEP
Sbjct  369  EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEP  428

Query  512  FPVVYDEDGEVHAVPESMLPIELPEVADYSPVTFDPEDRDSMPSSPLARATDWVEVELDL  571
            +P++  EDG   AVPES LP+ LP   D  P         +   SPLA  TDW+EV  + 
Sbjct  429  IPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTDWLEVTRE-  479

Query  572  GDGPKTYRRDINTMPNWAGSCWYQLRYVDPTNSETFCAPENEQYWMGPRPGEYGADDTGG  631
             DG K  RR+ NTMP+WAGS WY LRY+DP N+E +   E  + W+              
Sbjct  480  -DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWL-------------P  524

Query  632  VDLYVGGVEHAVLHLLYSRFWHKVLFDLGHVTSKEPYRKLFNQGYIEAYAYTDARGVYVP  691
            VD+YVGG EHAVLHLLY+RFWHKVL+DLG V +KEP++KLFNQG I + +Y D+RG  V+
Sbjct  525  VDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVA  584

Query  692  AEQVEERDGKHFFN---GEEVTQEYGKMGKSLKNVVTPDEMAENYGADTFRFYEMAMGPL  748
            +++VE RDG  FF+   GEE+ Q  +KM+KSLKNVV PD++ E+YGADT+R YEM MGPL
Sbjct  585  TDKVEKRDGS-FFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPL  643

Query  749  AMSRPWATKDVVGAHRFLQRLWRLVVDESTGELRVSTEDASEADRKVLHKTIAGVREDYA  808
              S +W+  ++ G+++FL+R+ RL+        +  TE+ S A  KV + T+ +V E+  
Sbjct  644  DASIAWSEEGLEGSRKFLDRVYRLITT------KEITEENSGALDKVYNETVKAVTEQVD  697

Query  809  EMRFNTAGAKL---IELNNHVTKVYGGATSTPRelaeplvlmlaplaphlaeelWHRL-G  864
            +M+FNTA A+L   ++  N   K++++ +         +V ++AP+APHL+EELW+ L +
Sbjct  698  QMKFNTAIAQLMVFVNAANKEDKLFSDYAKG-------FVQLIAPFAPHLGEELWQALTA  750

Query  865  HVDSLVQGPFPVVDEKYLVEDSVEYPIQVNGKVRSRVTVAASASTDEVQAAALADEKVAA  924
              +S+   P P  DE  LVE+ VE  +Q++GKV++++ VA   S +E+Q  ALA+EKV A
Sbjct  751  SGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQA  810

Query  925  MVGDGSPRKVIVVPGRLVNIVL  946
             +++    KVI VP +LVNIV+
Sbjct  811  EIAGKDIIKVIAVPNKLVNIVI  832


 Score =  134 bits (493),  Expect = 2e-32, Method: Compositional matrix adjust.
 Identities = 74/148 (50%), Positives = 103/148 (70%), Gaps = 10/148 (6%)

Query  22   IEQRWQDHWADQGTFHAPNPVGPLAVEGQPVPSDKLFVQDMFPYPSGSGLHVGHPLGFIS  81
            IE +WQ  WAD+ TF +          G   +  K++  DMFPYPSG+GLHVGHP G+ +
Sbjct  9    IEPKWQAFWADNHTFKT----------GTDASKPKFYALDMFPYPSGAGLHVGHPEGYTA  58

Query  82   TDVFARYHRMIGRNVLHTMGFDAFGLPAEQYAVQTGQHPRKTTEENIRTYLRQIRRLGLG  141
            TD+++R+ R  G+NVLH MG DAFGLPAEQYA++TG++P   T ENI  + RQI  LG++
Sbjct  59   TDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFS  118

Query  142  HDERRRISTIDPEYYRWTQWIFLQIFNS  169
             D  R ++T DP+YY+WTQWIF ++++ 
Sbjct  119  YDWDREVNTTDPNYYKWTQWIFTKLYEK  146

1494) ML5_3818 in NC_014815


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  514 bits (1939),  Expect = 1e-146, Method: Compositional matrix adjust.
 Identities = 347/735 (48%), Positives = 494/735 (68%), Gaps = 55/735 (7%)

Query  218  DHRLAYVSEAPVNWCPGLGTVLANEEVTADGRSERGNFPVFKRNLKQWMMRITAYGDRLL  277
            +  LAY +E PVNW   LGT +ANEEV +DG SERG +PV ++ ++QWM++ITAY++RLL
Sbjct  145  EKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLL  204

Query  278  EDLDTLDWPEPIKLQQRNWIGRSTGAHIDFPTEAA--PVRVFTTRPDTVFGATYMVLAPE  335
            EDL+ +DWPE+IK  QRNWIG+STGA++ F    +     VFTTRPDT+FGATY VLAPE
Sbjct  205  EDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPE  264

Query  336  HELVDVLTPATWPEGTRDAWTGGHAGPreaveayrkaaaakTDVERQADSKEKTGVFVGA  395
            H LVD +T +  +E+  D               Y++ A+ K+D+ R   +KEKTGV  G+
Sbjct  265  HALVDAITTSDQAEAVAD---------------YKRQASLKSDLARTDLAKEKTGVWTGS  309

Query  396  YATNPVTGGQIPIFIADYVLAGYGTGAIMAVPAQDERDWDFAEVFELPIVRTVQPPEGFD  455
            YA NPV G ++P+ IADYVLA+YGTGAIMAVPA+DERDW+FA  F+L I+  ++  +  +
Sbjct  310  YAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNV-E  368

Query  456  GKAYTGDGPAINSAAPERGIDLDGLGVTDAKARIIEWLEANGHGTGAVTWRLRDWLFSRQ  515
              A+T DG  INS        LDGL+ + A A+++EWLEA+G G   VT RLRDWLFSRQ
Sbjct  369  EAAFTEDGLHINSDF------LDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQ  422

Query  516  RYWGEPFPIVYDSTGAPIALPESMLPVELPEVEDFSPKTFDPEDADSNPETPLSRRRDWV  575
            RYWGEP+PI+    G++ A+PES LP+ LP   D+ P         +  E+PL+   DW+
Sbjct  423  RYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTDWL  474

Query  576  EVELDLGDGPKRYTRETNVMPQWAGSCWYELRYLDPTDSQRFADPENEAYWMGPRRDGDC  635
            EV  + G   +   RETN MPQWAGS WY LRY+DP +++++AD E    W+        
Sbjct  475  EVTREDGVKGR---RETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWL--------  523

Query  636  GGTDLYVGGAEHAVLHLLYARFWHKVLYDLGHVSSFEPFRRLFNQGMIQAYAFVDARGAY  695
               D+YVGGAEHAVLHLLYARFWHKVLYDLG V++ EPF++LFNQGMI + ++ D+RGA 
Sbjct  524  -PVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGAL  582

Query  696  VPAEEVVEVDGRWFHGET--EVRREYGKMGKSLKNVVTPDDMCAAYGADTFRVYEMSMGP  753
            V+++ V   DG  FH ET  E+ +  +KM+KSLKNVV PDD+   YGADT+RVYEM MGP
Sbjct  583  VATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGP  642

Query  754  LEVSRPWETRAVVGSYRFLQRVWRSVVDEQTGELRVTDEPADEVTRRLLHKAIDGVRADM  813
            L+ S +W   ++ GS +FL+RV R +   +     +T+E ++ +  ++ + ++ +V  ++
Sbjct  643  LDASIAWSEEGLEGSRKFLDRVYRLITTKE-----ITEENSGALD-KVYNETVKAVTEQV  696

Query  814  DGIRFNTAIAKLIELTNGLTRLARTPREVAEPLVLMVAPFAPHMAEELWRKL-GHGTSLA  872
            D ++FNTAIA+L+ + N+  +  +   + A  +V ++APFAPH++EELW+ L + G S++
Sbjct  697  DQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESIS  756

Query  873  YADFPVADPALLVAESVTYPVQVNGKVRGRIEVPADATEETVRATAL--EAVAGTLAGKE  930
            Y   P  D + LV + V   VQ++GKV++++ V+ D + E ++  AL  E V + +AGK+
Sbjct  757  YVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKD  816

Query  931  PRKVIVVKGRMVSVV  945
              KVI V  ++V++V
Sbjct  817  IIKVIAVPNKLVNIV  831


 Score =  131 bits (481),  Expect = 2e-31, Method: Compositional matrix adjust.
 Identities = 74/149 (50%), Positives = 102/149 (69%), Gaps = 11/149 (7%)

Query  24   IEHRWQDTWAREGTFHAPNPVGPLADPGHPRAGAEKLYVLDMFPYPSGAGLHVGHPLGYI  83
            IE +WQ  WA + TF +       +D++ P     K+Y LDMFPYPSGAGLHVGHP GY 
Sbjct  9    IEPKWQAFWADNHTFKTG------TDASKP-----KFYALDMFPYPSGAGLHVGHPEGYT  57

Query  84   GTDCYARYQRMAGRNVLHAMGFDAFGLPAEQYAVQTGTHPRTTTEANIERYREQLRRLGL  143
            +TD  +R++R  G+NVLH+MG DAFGLPAEQYA++TG +P   T  NI  ++ Q+  LG+
Sbjct  58   ATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGF  117

Query  144  GHDERRSVATIDTDFYRWTQWIFLQVFNS  172
            + D  R V T D ++Y+WTQWIF ++++ 
Sbjct  118  SYDWDREVNTTDPNYYKWTQWIFTKLYEK  146

1495) leuS in NC_009380


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  514 bits (1939),  Expect = 1e-146, Method: Compositional matrix adjust.
 Identities = 346/738 (47%), Positives = 491/738 (67%), Gaps = 59/738 (7%)

Query  221  LAYVSQAPVNWCPGLGTVLANEEVTADGRSERGNFPVFKRNLKQWMMRITAYGDRLLDDL  280
            LAY ++ PVNW   LGT +ANEEV +DG SERG +PV ++ ++QWM++ITAY++RLL+DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  281  EKLDWPEPIKLMQRNWIGRSTGAHIEFPTSAPDSDAEGEPRISVFTTRPDTIFGATYLVL  340
            E +DWPE+IK MQRNWIG+STGA++ F     D D      ++VFTTRPDT+FGATY VL
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKD------FTVFTTRPDTLFGATYAVL  261

Query  341  APEHDLVDTLVPTAWPAGVPQAWTGGQASPREAVAGYRKVAAAKTDLERQAETKEKTGVF  400
            APEH LVD++  +                  EAVA+Y++ A+ K+DL R   +KEKTGV 
Sbjct  262  APEHALVDAITTS---------------DQAEAVADYKRQASLKSDLARTDLAKEKTGVW  306

Query  401  IGSYATNPVTGAQIPIFIADYVLAGYGTGAIMAVPGQDERDWAFAEVFDLPIVRTVQPAE  460
             GSYA NPV G ++P+ IADYVLA+YGTGAIMAVP++DERDW FA  F+L I+  ++ ++
Sbjct  307  TGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGN  366

Query  461  GFAGKAYTGDGLAINSATPERGLDLNGLGVAEAKARTIAWLEAGGHGSGAVTYRLRDWLF  520
                 A+T DGL INS        L+GL+ A A A+ + WLEA G G+  VTYRLRDWLF
Sbjct  367  V-EEAAFTEDGLHINSDF------LDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLF  419

Query  521  SRQRYWGEPFPIVYDETGAAIAlpeellpvelpevDDFAPRTFDPSDAESNPETPLSRRR  580
            SRQRYWGEP+PI+  E G++ A+PE  LP+ LP   D+ P         +  E+PL+   
Sbjct  420  SRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPS--------GTGESPLANVT  471

Query  581  DWVEVELDLGDGPKRYTRETNVMPQWAGSCWYELRYLDPTNGDRFVDPEAERYWMGPRGE  640
            DW+EV  + G   +   RETN MPQWAGS WY LRY+DP N +++ D E  + W+     
Sbjct  472  DWLEVTREDGVKGR---RETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWL-----  523

Query  641  GDCGGTDLYVGGAEHAVLHLLYARFWHKVLYDLGHVSSFEPFRKLFNQGYIQAYAYTDAR  700
                  D+YVGGAEHAVLHLLYARFWHKVLYDLG V++ EPF+KLFNQG I + +Y D+R
Sbjct  524  ----PVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSR  579

Query  701  GAYVPAEEVVERSGTYYLGDV--QVNREYGKMGKSLRNVVTPDEMCAAYGADTFRVYEMS  758
            GA V+++ V  R G+++  +   ++++  +KM+KSL+NVV PD++   YGADT+RVYEM 
Sbjct  580  GALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMF  639

Query  759  MGPLEVSRPWETRAVVGSFRFLQRVWRAIVDERSGASRVVDVPADEATRRLLHRIVDGVR  818
            MGPL+ S +W   ++ GS +FL+RV R I      +++ +      A  ++ +  V +V 
Sbjct  640  MGPLDASIAWSEEGLEGSRKFLDRVYRLI------TTKEITEENSGALDKVYNETVKAVT  693

Query  819  GDMEAMRFNTTIAKLIELTNALTRLPETPREVAEPLVLMLAPFAPHVAEELWRRM-GHET  877
             +++ M+FNT+IA+L+ + NA  +      + A  +V ++APFAPH++EELW+ + +   
Sbjct  694  EQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGE  753

Query  878  SLTYADFPVADPALLVAESVTYPVQVNGKVRGRIEVPADAGQETVRaa--aleavaasla  935
            S++Y   P  D + LV + V   VQ++GKV++++ V+ D ++E ++    A E V A +A
Sbjct  754  SISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIA  813

Query  936  GKEPRKVIVVPGRMVSVV  953
            GK+  KVI VP ++V++V
Sbjct  814  GKDIIKVIAVPNKLVNIV  831


 Score =  134 bits (490),  Expect = 4e-32, Method: Compositional matrix adjust.
 Identities = 75/148 (51%), Positives = 103/148 (70%), Gaps = 11/148 (7%)

Query  24   IERRWQDTWEREGTFHAPNPTGPLADPEHPRAGAEKLYVLDMFPYPSGAGLHVGHPLGYI  83
            IE +WQ  W  + TF +       +D+  P     K+Y LDMFPYPSGAGLHVGHP GY 
Sbjct  9    IEPKWQAFWADNHTFKTG------TDASKP-----KFYALDMFPYPSGAGLHVGHPEGYT  57

Query  84   GTDCFARYQRMAGRNVLHAMGFDAFGLPAEQYAVQTGTHPRTTTEANIARYKAQLRRLGL  143
            +TD ++R++R  G+NVLH+MG DAFGLPAEQYA++TG +P   T  NIA +K Q+  LG+
Sbjct  58   ATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGF  117

Query  144  AHDERRSVATIDADFYRWTQWVFLQIYN  171
            + D  R V T D+++Y+WTQW+F ++Y+
Sbjct  118  SYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1496) leuS in NC_008095


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  514 bits (1938),  Expect = 1e-146, Method: Compositional matrix adjust.
 Identities = 348/861 (41%), Positives = 536/861 (63%), Gaps = 69/861 (8%)

Query  5    YEPQAIEGKWQTRWDDAGIFRAGSRPGAPKKYVLEMLPYPSGK-MHMGHVRNYLLGDVYA  63
            Y+  AIE KWQ+ W D   F++G+ ++ PK Y L+M+PYPSG  +H+GH   Y   D+ +
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYFRMKGFDVLHPMGWDALGLPAENAAIKDGVHPAVRTAENIASFKKEIKSLGYCYDWDR  123
            R+ R +G +VLHPMGWDA+GLPAE+ A+  G +PA  TAENIA+FK++I++LG+ YDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVNTSDPEYYRWNQWFFIQMLERGLVYRRFSKVNWCTGCHTVIANEQV-KDGVCERCDSP  182
            EVNT+DP+YY+W QW+F ++ E+GL Y     VNW     T IANE+V  DG  ER + P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VVDKEMPEWAFRITRFSQELLDALDTLKEWPHRITAAQRNWIGRSDGAEADFRVQGHDTA  242
            VV K M +W ++IT +++ LL+ L+ + +WP+ I   QRNWIG+S GA+  F+V++ D  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LRVFTTRIDTIFGCTYVVLAPDHELVAQVTTPERRAEVEAFAKRMAAQSKTERLGEGTEK  302
            + VFTTR DT+FG TY VLAP+H LV  +TT+++   V  + ++ + +S   R + + EK
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEK  302

Query  303  EGVFTGAYAENPFTGQAVPIWIANFVLSDYGTGAVMSVPAHDERDFAFARKYSLPVKVVI  362
             GV TG+YA NP  G+ +P+WIA++VL+ YGTGA+M+VPAHDERD  FA++++L +  V+
Sbjct  303  TGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL  362

Query  363  QPASGDKLPPGDKLEAAYTEYGVLEDSGAYTGQTSEQARQAMAALLEKDGKGKATVTYRQ  422
            + ++ +        EAA+TE G+  +S+   G     A   M   LE +G G+  VTYR 
Sbjct  363  EGGNVE--------EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRL  414

Query  423  KDWGFSRQRYWGTPIPIVYCEKCDPDRNGIPVPVAQLPVRLPEIDTQAVLTGKGEPPLAK  482
            +DW FSRQRYWG PIPI+  E    D  + +VP ++LP+ LP +  +   +G GE+PLA+
Sbjct  415  RDWLFSRQRYWGEPIPIIHWE----DGTSTAVPESELPLVLP-VTKDIRPSGTGESPLAN  469

Query  483  VASWVNTSCPKCGGPARREAETMDTFVDSCWYFARYLSPHYDAAPFDPKEAQRFLPVDIY  542
            V+ W++ +    G  +RRE++TM    +S WY+ RY+ PH      D    ++ LPVDIY
Sbjct  470  VTDWLEVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIY  528

Query  543  VGGPEHAVMHLLYFRFWTRVMKLLGLSPVDEPVKRLITQGIVNGP---DGR---------  590
            VGG+EHAV+HLLY RFW +V+  LG+ P  EP ++L+ QG++ G    D+R         
Sbjct  529  VGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKV  588

Query  591  ---------------------KMSKRWGNVVAPASIVQKYGADTARAYVLFAGPPERDFD  629
                                 KMSK   NVV P  +V++YGADT R Y +F GP +  + 
Sbjct  589  EKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIA  648

Query  630  WSDEQVEGVYRFLKRVWalaathqaaaagaTHDGPYEGKALEILRAAHKTLKRVGEAIER  689
            WS+E +EG  +FL RV              T     E ++  + +  + T+K V E +++
Sbjct  649  WSEEGLEGSRKFLDRV----------YRLITTKEITEENSGALDKVYNETVKAVTEQVDQ  698

Query  690  LSFNTAIAGIMEGLNALYALGTPetaaekaamaeaVRLLAVVLTPFTPHIADEIAEAYGS  749
            + FNTAIA +M  +NA        +  E    ++  + +  +++PF+PH+++E+ +A  +
Sbjct  699  MKFNTAIAQLMVFVNA--------ANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTA  750

Query  750  KDFTVA-QSWPEFDPALVVDDVIPYAVQVNGKLraeirvaadaaeadvraaaeadeKVQV  808
             + +++  +WP +D + +V++ +   VQ++GK++A + VA D +  +++  A A+EKVQ 
Sbjct  751  SGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQA  810

Query  809  ALAGKTLRKFVFVPKRLVNFV  829
             +AGK + K + VP++LVN+V
Sbjct  811  EIAGKDIIKVIAVPNKLVNIV  831

1497) leuS in NC_017731


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  514 bits (1938),  Expect = 1e-146, Method: Compositional matrix adjust.
 Identities = 348/866 (41%), Positives = 543/866 (63%), Gaps = 48/866 (5%)

Query  5    YRPEDIEPKVQRHWDEKATFKVTEDNSKEKYYCLSMLPYPSGR-LHMGHVRNYTMGDVIS  63
            Y    IEPK Q  W ++ TFK   D SK K+Y L M+PYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRLLGKNVLQPIGWDAFGLPAEGAAVKNKTAPAPWTYANIDYMKGQLKMLGFGYDWDR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T  NI   K Q++ LGF+YDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVTTCTPEYYRWEQWFFTKLYEKGLVYKKTSAVNWCPHDLTVLANEQVI-DGCCWRCDTP  182
            EV T  P+YY+W QW+FTKLYEKGL Y    +VNW  +  T +ANE+V+ DG   R + P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITDYAEEllndldklddWPEQVKTMQRNWIGRSEGVEITFNVADRDDK  242
            V RK + QW +KIT YA E L +     DWPE +K MQRNWIG+S G ++TF+V D D  
Sbjct  184  VVRKPMRQWMLKITAYA-ERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGATYVAVAAGHPlaleaaeknaelanFIDECRNTKTAEADMA----TM  298
            +TV+TTRPDT+ GATY  +A+ H+L    +  +   A  + + +   +  +D+A    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEA--VADYKRQASLKSDLARTDLAK  300

Query  299  DKKGMPTGLYVIHPLTQEKLPIWVANFVLMEYGTGAVMAVPAHDQRDWEFAHKYNLPLKV  358
            +K G+ TG Y I+P+    +P+W+A++VL  YGTGA+MAVPAHD+RDWEFA ++NL +  
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VIADAEGNEPDISQEAMTEKFALINSGEFSGLDNTAGFNAIADKLVAIGVGQRKVNYRLR  418
            V+ +++ +E+ ++++++      INS+ + GLD+++++  + + L A GVG+ +V YRLR
Sbjct  361  VLEGGNVEEAAFTEDGLH-----INSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  419  DWGVSRQRYWGAPIPMATLEDGTVVPVPEDQLPVILP--EDVEMDGIT-SPIKADPEWAK  475
            DW  SRQRYWG PIP+   EDGT  +VPE +LP++LP   D+   G   SP+    +W  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  476  TT-INGQPALRETDTFDTFMESSWYYARYTCPQFDEGMLDPAAANYWLPVDQYIGGIEHA  534
             T  +G  + RET+T      SSWYY RY  P+  E + D    + WLPVD Y+GG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  535  IMHLMYFRFFHKLMRDAGLVNSDEPAKRLLCQGMVLADAFYYTGSDGQRVWVSPSDVTVE  594
            ++HL+Y RF HK++ D G+V + EP ++L+ QGM+L+ ++     D++   V+   V   
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY----RDSRGALVATDKV---  588

Query  595  RDDKNRIIKAVDTEGHELVYTGMSKMSKSKNNGIDPQLMVEKYGADTVRLFMMFAAPPEL  654
             + ++  +  V+T G+EL   + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P + 
Sbjct  589  -EKRDGSFFHVET-GEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  655  TLEWQESSVEGANRFVRRVWRIVHEHSQKGATQPLDVSTLTTEQKDLRRDLHKTIAKVTD  714
            ++ W E ++EG+ +F+ RV R++   + K  T+         +   L +  + T+  VT+
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLI---TTKEITE--------ENSGALDKVYNETVKAVTE  694

Query  715  DFDRRYAFNTAIAAIMEFMNKLVRAPQETEQDRALMQESLEAITLMLSPIIPHACFEMWK  774
            + D+   FNTAIA +M F+N        ++++  L  +   ++  +++P+ PH   E+W+
Sbjct  695  QVDQM-KFNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  775  AL-GHTDDVDFASWPVADEKAMVDDTKLVVIQVNGKVRGRITVPADAVQDFVLDMATKEY  833
            AL +  + + + +WP  DE  +V++   +V+Q++GKV++++ V+ D  ++ + ++A  + 
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  834  SVSKYLEGVTIRKVIYVPGKLLNLVV  859
             V   + G  I KVI VP KL+N+V+
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVI  832

1498) Mar181_1146 in NC_015559


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  514 bits (1940),  Expect = 8e-147, Method: Compositional matrix adjust.
 Identities = 348/856 (41%), Positives = 530/856 (62%), Gaps = 72/856 (8%)

Query  5    YNPQQIEQAAQSFWDENKVFKAVADSNKEKFYCLSMFPYPSGR-LHMGHVRNYTIGDVIS  63
            Y+   IE   Q+FW +N  FK+ +D++K KFY L MFPYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMQGKNVLQPMGWDAFGLPAENAAIKHKTAPAKWTTENVAYMKGQLKELGFAYDWDR  123
            R++R QG NVL+PMGWDAFGLPAE+ A+     PA  T+EN+A  K Q++ LGF+YDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EIATCTPEYYKWEQWFFTQLIEKGLAYKKTAAVNWCPHDQTVLANEQV-EDGGCWRCGTT  182
            E+ T  P+YYKW QW+FT+L EKGLAY    +VNW  +  T +ANE+V  DG   R G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VEKKEISQWFIRITDYAEEllndldqlddWPEKVKAMQRNWIGRSEGLEFSFEVEGKEDR  242
            V +K + QW ++IT YA E L +  +  DWPE +K MQRNWIG+S G + +F V + +  
Sbjct  184  VVRKPMRQWMLKITAYA-ERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LSVYTTRPDTVMGVTYVAVATQHP--lsleaaesnaelanFIAESKLMSTTEADMATVDK  300
            ++V+TTRPDT+ G TY  +A +H+   ++ +++    +A++  ++ L S       + +K
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEK  302

Query  301  KGIDTGFKAIHPITGEAVPVFAANFVLMEYGSGAVMSVPAHDQRDFEFAKKYDLPIKQVI  360
             G+ TG  AI+P+ G  +PV  A++VL  YG+GA+M+VPAHD+RD EFAK+++L I  V+
Sbjct  303  TGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL  362

Query  361  QPAGEETANIETEAYTDKGVLCNSGEFDGLAFKEAFDAIAAWMTERNLGEVKVNYRLRDW  420
                 E +N+E  A+T+ G+  NS+ +DGL    A+  +  W+    +G+ +V YRLRDW
Sbjct  363  -----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDW  417

Query  421  GVSRQRYWGTPIPTINLKDGSVVPVPADQLPVELPT--DVVMDGV-NSPIKNNPD-FSAI  476
              SRQRYWG PIP I+  DG+  +VP  +LP+ LP   D+   G  +SP+ N  D +   
Sbjct  418  LFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT  477

Query  477  MFNGEEAERETDTFDTFMESSWYFARYCCPDATDAMLTEE-ANYWLPVDQYVGGVEHAIL  535
              +G  + RET+T      SSWY+ RY  P+ T+ +  EE  + WLPVD YVGG EHA+L
Sbjct  478  REDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVL  537

Query  536  HLLYSRFFHKLLRDAGLVNSDEPFKRLLTQGMV-------------------NKDGT---  573
            HLLY+RF HK+L D G+V + EPF++L+ QGM+                   ++DG+   
Sbjct  538  HLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFH  597

Query  574  ------------KMSKSKGNTVDPQEMIEKYGADTVRLFIMFSAPPEQSLEWNDAGVDGA  621
                        KMSKS  N V+P++++E+YGADT+R++ MF +P + S+ W++ G++G+
Sbjct  598  VETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGS  657

Query  622  SRFLRRLWAL-SLRHVNGGKAGDLNIEALNGAQKALRRKTHETIQKVTDDIERRQTFNTA  680
             +FL R+  L + +++   ++G L+            +  +ET++ VT+++++ + FNTA
Sbjct  658  RKFLDRVYRLITTKEITEENSGALD------------KVYNETVKAVTEQVDQMK-FNTA  704

Query  681  IAAVMELCNDISKFEDSSELGLAVEREALEATILLLSPIVPHIAHQLWMDLGNT--NIVD  738
            IA +M + N  +K ED       +  +   + + L++P+ PH++++LW  L  +  +I  
Sbjct  705  IAQLMVFVNAANK-EDK------LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISY  757

Query  739  TPWPSLDEAALVKDELTIVVQVLGKKRAELTVSASADNKTIETEALAHPNVTKFLEGKTV  798
             PWPS DE+ LV +++ IVVQ+ GK +A L V+       ++  ALA+ +V   + GK +
Sbjct  758  VPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDI  817

Query  799  RKVIVVPGRLVNIVAN  814
             KVI VP +LVNIV +
Sbjct  818  IKVIAVPNKLVNIVIK  833

1499) leuS in NC_018495


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  514 bits (1939),  Expect = 9e-147, Method: Compositional matrix adjust.
 Identities = 342/848 (41%), Positives = 542/848 (64%), Gaps = 76/848 (8%)

Query  2    YNHNLIEEKWLKKWKNKDVNRFESDSNKKKYYVLDMFPYPSAAGLHLGHVRAYTITDVIS  61
            Y+H  IE KW   W +++  +  +D++K K+Y LDMFPYPS+AGLH+GH  +YT TD++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  62   RYYKAKGFNVIHPIGFDAFGLPAEQYAINSNQNPGSWTDQNINNFINQLTSFGFDYDYHL  121
            R+ +A+G NV+HP+G DAFGLPAEQYA+++ ++P+  T +NI NF  Q+ ++GF YD + 
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  122  SLKTTDPRYYKYTQWIFSELFKANLAELVDIDVNWCEQLGTVLANEEVLIDSNGNAVSER  181
             ++TTDP YYK TQWIF+ L+   LA   ++ VNW E+LGT +ANEEVL D+     SER
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGT----SER  179

Query  182  GSFSVEKRKMKQWVLKITTFADALLEGLDTLDWPEPIKEMQRNWIGKSKGVTINFQLKDH  241
            G+++V ++ M+QW+LKIT++A+ LLE+L+ +DWPE+IK+MQRNWIGKS G  + F++KD 
Sbjct  180  GGYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDT  239

Query  242  KEAIAIFTTKPQTIFGVSFLAVSTNHWLAKKIAETNKKVASFlkkqlqktttlkqkATLY  301
               +++FTT+P+T+FG ++  ++ +H L   I+ +++  A    K+     +   ++ L 
Sbjct  240  DKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA  299

Query  302  -DGIDLLTN--AIHPLTNELIPVYVANYVIEGYGTDAIMGVGAHNENDNFFARKQKLKII  358
             +  ++ T   AI+P+    +PV +A+YV+ +YGT+AIM+V AH+E D  FA++ +L II
Sbjct  300  KEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDII  359

Query  359  NVIDKKERLQNSFAYNGLT---------TKEAQVAITNE-LISQNKAKLTTVYKLRDWIF  408
             V++  +  + +F+ +GL           K + +A   E L ++  ++    Y+LRDW+F
Sbjct  360  PVLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLF  419

Query  409  SRQRYWGEPFPIIF--DENNTPHlveqlpvelplleNYKPDGSGNSPLMRNQAWVNIVKD  466
            SRQRYWGEP+PII   D  +T+    +LP+ LP+  + +P G+G+SPL     W+++ ++
Sbjct  420  SRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRE  479

Query  467  N-IHYQRETNTMPQWAGSCWYYLGYLMLIKNPNFWPIDSKEAKKLFDQYLPVDLYVGGAE  525
            + +  +RETNTMPQWAGS WYYL Y+    +P+    +      L+ Q LPVD+YVGGAE
Sbjct  480  DGVKGRRETNTMPQWAGSSWYYLRYI----DPH--NTEKLADEELLKQWLPVDIYVGGAE  533

Query  526  HAVLHLLYARFWHKFLFDKKLVSTKEPFQKLINQGMVLGPD-------------------  566
            HAVLHLLYARFWHK L+D  +V+TKEPFQKL+NQGM+LG                     
Sbjct  534  HAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDG  593

Query  567  --------------GKKMSKSKGNTINPTPLVDSHGADALRLYLMFMGPISASLTWNDEG  612
                            KMSKS  N +NP  +V+  GAD+LR+Y MFMGP+ AS++W++EG
Sbjct  594  SFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEG  653

Query  613  LNGMRRWLDRVYNFFFNHAVVTDQVSQETTFAYNLFLKNSYCHLDKHELNLVISEMMIFL  672
            L+G R+ LDRVY ++     +T++ S      YN  +K    ++D+  +N  I+++M+F+
Sbjct  654  LEGSRKFLDRVYRLITTKE-ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFV  712

Query  673  NFLYKTKKISLNYAKGFLTVLSFFAPFLAEELNEKCGLEPFVVKQAISLVDYQLFETAK-  731
            N   K  K+  +YAKGF+ +++ FAP L+EEL +  +L +    ++IS V    ++ +K 
Sbjct  713  NAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ--ALTA--SGESISYVPWPSYDESKL  768

Query  732  ----TKVILSINGKFKA----AKEFTKGSLEIDVLESFKQDKEINDILNQPIERVVYVQD  783
                  +++ I+GK KA    AK++++  L+   L +   +K   +I  + I +V+ V +
Sbjct  769  VENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALAN---EKVQAEIAGKDIIKVIAVPN  825

Query  784  RIINVLLK  791
            +++N+++K
Sbjct  826  KLVNIVIK  833

1500) leuS in NC_018497


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  514 bits (1939),  Expect = 9e-147, Method: Compositional matrix adjust.
 Identities = 342/848 (41%), Positives = 542/848 (64%), Gaps = 76/848 (8%)

Query  2    YNHNLIEEKWLKKWKNKDVNRFESDSNKKKYYVLDMFPYPSAAGLHLGHVRAYTITDVIS  61
            Y+H  IE KW   W +++  +  +D++K K+Y LDMFPYPS+AGLH+GH  +YT TD++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  62   RYYKAKGFNVIHPIGFDAFGLPAEQYAINSNQNPGSWTDQNINNFINQLTSFGFDYDYHL  121
            R+ +A+G NV+HP+G DAFGLPAEQYA+++ ++P+  T +NI NF  Q+ ++GF YD + 
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  122  SLKTTDPRYYKYTQWIFSELFKANLAELVDIDVNWCEQLGTVLANEEVLIDSNGNAVSER  181
             ++TTDP YYK TQWIF+ L+   LA   ++ VNW E+LGT +ANEEVL D+     SER
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGT----SER  179

Query  182  GSFSVEKRKMKQWVLKITTFADALLEGLDTLDWPEPIKEMQRNWIGKSKGVTINFQLKDH  241
            G+++V ++ M+QW+LKIT++A+ LLE+L+ +DWPE+IK+MQRNWIGKS G  + F++KD 
Sbjct  180  GGYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDT  239

Query  242  KEAIAIFTTKPQTIFGVSFLAVSTNHWLAKKIAETNKKVASFlkkqlqktttlkqkATLY  301
               +++FTT+P+T+FG ++  ++ +H L   I+ +++  A    K+     +   ++ L 
Sbjct  240  DKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA  299

Query  302  -DGIDLLTN--AIHPLTNELIPVYVANYVIEGYGTDAIMGVGAHNENDNFFARKQKLKII  358
             +  ++ T   AI+P+    +PV +A+YV+ +YGT+AIM+V AH+E D  FA++ +L II
Sbjct  300  KEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDII  359

Query  359  NVIDKKERLQNSFAYNGLT---------TKEAQVAITNE-LISQNKAKLTTVYKLRDWIF  408
             V++  +  + +F+ +GL           K + +A   E L ++  ++    Y+LRDW+F
Sbjct  360  PVLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLF  419

Query  409  SRQRYWGEPFPIIF--DENNTPHlveqlpvelplleNYKPDGSGNSPLMRNQAWVNIVKD  466
            SRQRYWGEP+PII   D  +T+    +LP+ LP+  + +P G+G+SPL     W+++ ++
Sbjct  420  SRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRE  479

Query  467  N-IHYQRETNTMPQWAGSCWYYLGYLMLIKNPNFWPIDSKEAKKLFDQYLPVDLYVGGAE  525
            + +  +RETNTMPQWAGS WYYL Y+    +P+    +      L+ Q LPVD+YVGGAE
Sbjct  480  DGVKGRRETNTMPQWAGSSWYYLRYI----DPH--NTEKLADEELLKQWLPVDIYVGGAE  533

Query  526  HAVLHLLYARFWHKFLFDKKLVSTKEPFQKLINQGMVLGPD-------------------  566
            HAVLHLLYARFWHK L+D  +V+TKEPFQKL+NQGM+LG                     
Sbjct  534  HAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDG  593

Query  567  --------------GKKMSKSKGNTINPTPLVDSHGADALRLYLMFMGPISASLTWNDEG  612
                            KMSKS  N +NP  +V+  GAD+LR+Y MFMGP+ AS++W++EG
Sbjct  594  SFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEG  653

Query  613  LNGMRRWLDRVYNFFFNHAVVTDQVSQETTFAYNLFLKNSYCHLDKHELNLVISEMMIFL  672
            L+G R+ LDRVY ++     +T++ S      YN  +K    ++D+  +N  I+++M+F+
Sbjct  654  LEGSRKFLDRVYRLITTKE-ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFV  712

Query  673  NFLYKTKKISLNYAKGFLTVLSFFAPFLAEELNEKCGLEPFVVKQAISLVDYQLFETAK-  731
            N   K  K+  +YAKGF+ +++ FAP L+EEL +  +L +    ++IS V    ++ +K 
Sbjct  713  NAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ--ALTA--SGESISYVPWPSYDESKL  768

Query  732  ----TKVILSINGKFKA----AKEFTKGSLEIDVLESFKQDKEINDILNQPIERVVYVQD  783
                  +++ I+GK KA    AK++++  L+   L +   +K   +I  + I +V+ V +
Sbjct  769  VENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALAN---EKVQAEIAGKDIIKVIAVPN  825

Query  784  RIINVLLK  791
            +++N+++K
Sbjct  826  KLVNIVIK  833

1501) Deipe_0136 in NC_019793


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  513 bits (1937),  Expect = 1e-146, Method: Compositional matrix adjust.
 Identities = 357/849 (43%), Positives = 529/849 (63%), Gaps = 60/849 (7%)

Query  23   YNPHAIEPKWQQRWDAQGLYTFDESSEKPKHYALTMFPYPSG-NLHIGHWYAYCVPDARA  81
            Y+  AIEPKWQ  W  +  +  +  + KPK YAL MFPYPSG  LH+GH  +Y   D  +
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  82   RWMRMNGWNVLFPMGFDAFGLPAENAAIKRGINPRSWTYDNIAYMTQQFRRMGTMIDWSR  141
            R  R +G NVL PMG DAFGLPAE+ A+  G +P   T +NIA   +Q+  +G   DW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  142  QFATCDPEYYRWNQWFFVQFYRRGLAYKKESFVNWDPVDQTVLANEQVI-DGRGDRSGAL  200
            +  T DP+YY+W QW+F ++Y +GLAY  E  VNW     T +ANE+V+ DG ++R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  201  IERRLMSQWHFKITEYAEELL-DFSKTDMPERVRLMQTNWIGKSQGAEIDFETPAGIE--  257
            + R+ M QW +KIT YAE LL D+   D PE ++ MQ NWIGKS GA++ F         
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  258  TVFTTRPDTIMGATFLVLAPEHAKVKALTTDAQRAEVEAYIDAASRLSEIDRQAEGREKT  317
            TVFTTRPDT+ GAT+ VLAPEHA V A+TT  Q   V  Y   AS  S++ R   ++EKT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  318  GVFTGSFATHPISRHQVPIWIADYVLATYGTGSIMAVPSGDQRDFEFAKKYELPIVEVVR  377
            GV TGS+A +P++  ++P+WIADYVLA+YGTG+IMAVP+ D+RD EFAK+++L I+ V+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  378  PSGGEPFDPATATEAFSGDGIIVNSGELDGLPGGKAHIGPVIERLQHSGIARAKTTYRLR  437
             +  E         AF+ DG+ +NS+ LDGL  + A I+ ++E+L+  G++  + TYRLR
Sbjct  364  GGNVE-------EAAFTEDGLHINSDFLDGLDKASA-IAKMVEWLEAEGVGNENVTYRLR  415

Query  438  DWLLSRQRYWGTPIPIVYCEQCGTVPVPEDQLPVLLPDNVEFLP--TGQSPLKLSTEWRQ  495
            DWL+SRQRYWG PIPI+  E+  + +VPE +LP++LP   ++ P  TG+SPL   T+W +
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  496  TTCPQCAGPAERDTDTMDTFVDSSWYMYRFLNPDKIDGPIDTAKAEHFMPIDLYTGGIEH  555
             T  + +  + R+T+TM    +SSWY  R+++P++ +   D     + +P+D+Y GG EH
Sbjct  476  VTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEH  534

Query  556  AILHLLYSRFWTKATRDLGLISSDEPFAALRNQGIILG----------------------  593
            A+LHLLY+RFW K   DLG++++ EPF  L NQG+ILG                      
Sbjct  535  AVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGS  594

Query  594  -----------EDNEKMSKSRGNVIDPDNLVREYGVDAVRVYLAFIAPWEVGGPWSASGI  642
                       +   KMSKS  NV++PD++V +YG D++RVY  F++P + + +WS  G+
Sbjct  595  FFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGL  654

Query  643  NGPAKWLSRVWSLFFDEVEGPEEHIGEAELRNKVHATLKKVGHDFDRLSFNTIIAALMEL  702
            +G+ K L RV  L +   E  EE+ G   L +  + T+K V ++ D++ FNT IA LM +
Sbjct  655  EGSRKFLDRVYRL-ITTKEITEENSG--ALDKVYNETVKAVTEQVDQMKFNTAIAQLMVF  711

Query  703  TNTLVKAKRSAVFGSPAWDESLRLFNLMLAPVTPHLAEEIWTE-RGGDASVHLQSWPSVD  761
             N+  K  +  +F+     +  + F  ++AP +PHL+EE+W    +++ S+   +WPS D
Sbjct  712  VNAANKEDK--LFS-----DYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYD  764

Query  762  EAALVKGTMTIAVQVSGKLRGQIEVVTGADKDLIMAAAHAEESVRKFVEGKEIVKEIYVP  821
            E+ LV   + I VQ+ GK+++++ V  +  ++ +   A A+E V+  + GK+I+K I VP
Sbjct  765  ESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVP  824

Query  822  GKIVNIVVR  830
             K+VNIV++
Sbjct  825  NKLVNIVIK  833

1502) leuS in NC_008268


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  513 bits (1937),  Expect = 2e-146, Method: Compositional matrix adjust.
 Identities = 349/737 (48%), Positives = 501/737 (68%), Gaps = 65/737 (8%)

Query  220  LVYHSDSMVNWCPGLGTVLANEEVTADGRSDRGNFPVFRKHLQQWMMRITAYSDRLVDDL  279
            L Y+++  VNW   LGT +ANEEV +DG S+RG +PV RK ++QWM++ITAY++RL++DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  280  EYLDWPEKVKTMQRNWIGRSHGAQVKFQADG--HEIEVFTTRPDTLFGATYVTLAPEHEL  337
            E +DWPE +K MQRNWIG+S GA+V F+  +   ++ VFTTRPDTLFGATY  LAPEH L
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  338  VDDIVAAEWPRGVDSRWTGGaatpaeavaaYRKSIAAKSDLERQEY-KEKTGVFLGTYAV  396
            VD I +++ + +V                 Y++  + KSDL R +  KEKTGV  G+YA+
Sbjct  268  VDAITTSDQAEAVAD---------------YKRQASLKSDLARTDLAKEKTGVWTGSYAI  312

Query  397  NPVNGHKLPVFIADYVLTGYGTGAIMAVPGHDHRDYEFATEFGLDIVEVISGGDLTKDAY  456
            NPVNG  +PV IADYVL++YGTGAIMAVP+HD+RD EFA +F LDI+ V+ GG++   A+
Sbjct  313  NPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEAAF  372

Query  457  TGDGTIVNSDFLNGMSVADAKKAITERLEADGTGKGTIQYKLRDWLFARQRYWGEPFPIV  516
            T DG  +NSDFL+G+  A A   + E+LEA+G G+  + Y+LRDWLF+RQRYWGEP+PI+
Sbjct  373  TEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPII  432

Query  517  YDAEGNAHALPESSLPVELPEVEDYAPVsfdpddassepsppLAKAVDWVNVELDLGDGL  576
               +G + A+PES LP+ LP   D  P        S+   +PLA+  DW++V  +  DG+
Sbjct  433  HWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTDWLEVTRE--DGV  482

Query  577  QTYRRDTNVMPQWAGSSWYQLRYIDPTNPDVFCDKENERYWTGPRPEIHGPNDPGGVDLY  636
            +  RR+TN MPQWAGSSWY LRYIDP N + + D E  + W               VD+Y
Sbjct  483  KG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWL-------------PVDIY  528

Query  637  VGGVEHAVLHLLYSRFWHKVLFDLGYVSSSEPYRRLYNQGYIQAYAYTDARGVYVPADEV  696
            VGG EHAVLHLLY+RFWHKVL+DLG V++ EP+++L+NQG I + +Y D+RG  V++D V
Sbjct  529  VGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKV  588

Query  697  EEKDGKFFH--QGVEVNREYGKMGKSLKNSVSPDEICEEYGADTLRVYEMSMGPLDTSRP  754
            E +DG FFH   G E+++  +KM+KSLKN V+PD++ E+YGADTLRVYEM MGPLD+S +
Sbjct  589  EKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIA  648

Query  755  WATKDVVGAQRFLQRAWRVVVDEESGALRVTDDAPAEDTLRALNKAIAGVSEDYTALRDN  814
            W+  ++ G+++FL+R  R++   E     +T++ ++    +  N ++ +V+E+   ++ N
Sbjct  649  WSEEGLEGSRKFLDRVYRLITTKE-----ITEENSGALD-KVYNETVKAVTEQVDQMKFN  702

Query  815  TAAAKLIEYTN------HLTKAYPGGAPRSvveplvlmlaplaphlaeelWSRL-GHEKS  867
            TA A+L+ + N       L   Y+ G  +        ++AP+APHL+EELW  L +   S
Sbjct  703  TAIAQLMVFVNAANKEDKLFSDYAKGFVQ--------LIAPFAPHLGEELWQALTASGES  754

Query  868  LAHGPFPVAEEKWLVEDTVEYPIQVNGKVRSRVTVAADAPREEIEKIALADDKIVALLDG  927
            ++  P P  +E  LVE+ VE  +Q++GKV++++ VA D +REE++ +ALA++K+ A + G
Sbjct  755  ISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAG  814

Query  928  QDPRKVIVVPGKMVNIV  944
            +D  KVI VP K+VNIV
Sbjct  815  KDIIKVIAVPNKLVNIV  831


 Score =  133 bits (487),  Expect = 7e-32, Method: Compositional matrix adjust.
 Identities = 74/144 (52%), Positives = 101/144 (71%), Gaps = 7/144 (4%)

Query  27   IEQRWQDRWSEEGTFNAPNPVGPLAGDVPADKLFVQDMFPYPSGTGLHVGHPLGYIATDV  86
            IE +WQ  W+++ TF++       + D +  K++  DMFPYPSG+GLHVGHP GY ATD+
Sbjct  9    IEPKWQAFWADNHTFKT-------GTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDI  61

Query  87   FARYHRMQGHNVLHTLGYDAFGLPAEQYAVQTGTHPRTTTEANIVNMKRQLRRLGLGHDE  146
            ++R+ R QGHNVLH +G DAFGLPAEQYA++TG +P   T  NI N KRQ+  LG++ D 
Sbjct  62   LSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDW  121

Query  147  RRTFATTDTDFYHWTQWIFLQIHD  170
             R   TTD ++Y WTQWIF ++ +
Sbjct  122  DREVNTTDPNYYKWTQWIFTKLYE  145

1503) leuS in NC_010814


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  513 bits (1936),  Expect = 2e-146, Method: Compositional matrix adjust.
 Identities = 355/857 (42%), Positives = 534/857 (63%), Gaps = 67/857 (7%)

Query  7    YTPAGVEAKWQQQWEAQKTFKVTEDPSRKKYYLLEMFPYPSGR-IHMGHVRNYSIGDVVG  65
            Y  +++E+KWQ  W  + TFK   D+S+ K+Y L+MFPYPSG  +H+GH   Y+  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  66   RFKRMRGFNVLHPMGWDAFGMPAENAAIKNNCHPAAWTYENMAYMRDQLKQMGLSYDWDR  125
            RFKR +G NVLHPMGWDAFG+PAE+ A+    +PA  T EN+A  + Q++ +G+SYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  126  ELATCDVSYYRWEQKLFLEMYKRGIAYKKQSFVNWCPSCETVLANEQV-EDGGCWRCDTE  184
            E+ T D +YY+W Q +F  +Y +G+AY  +  VNW     T +ANE+V  DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  185  VVQKELEQWFFKITDYAEELLDFTNKLPGWPERVLVMQRNWIGKSTGCEIDFALDGRDGA  244
            VV+K + QW +KIT YAE LL+  + + +WPE +  MQRNWIGKSTG ++ F + + D  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  245  IRVFTTRPDTLFGATFMSLAPEHPMALELTAPERRAEVEAFIDKVKKTDRIARTSDDQEK  304
            + VFTTRPDTLFGAT+  LAPEH++   +T++++   V  +  +      +ART   +EK
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEK  302

Query  305  EGVFTGSYCINPTNGRKMPVYLANFVLVEYGTGAVMAVPTHDQRDFEFAKKYDLPLVVVI  364
             GV TGSY INP NG+ MPV +A++VL  YGTGA+MAVP+HD+RD EFAK+++L ++ V+
Sbjct  303  TGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL  362

Query  365  QPEGETLDPATMTAAYTEVGTMVNSAQFDGQKSDAAKDSIATWMEGQGKGKKTVNFRLRD  424
              EG  ++     AA+TE G  +NS  +DG    +A   +  W+E++G G+  V +RLRD
Sbjct  363  --EGGNVE----EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  425  WGVSRQRYWGSPIPIIY--CDCCGvvpvpdkdlpvvlprdvHFTGEGGSPLATLESFTKV  482
            W  SRQRYWG PIPII    +    VP ++  L + + +D++ +G G SPLA +     V
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  483  DCPLCGKPARRETDTMDTFVESSWYFLRYCCPDFEDGMLDKARAQYWMSVDQYIGGIEHA  542
                 G  +RRET+TM     SSWY+LRY  P+  + + D    + W++VD Y+GG EHA
Sbjct  477  TRE-DGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  543  VLHLLYARFFTKVMRDLGYVDVDEPFTNLLTQGMVI-------------------KDG--  581
            VLHLLYARF  KV+ DLG V   EPF +L+ QGM++                   +DG  
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSF  595

Query  582  -------------AKMSKSKGNVVDPDALIKRYGADTARLFSLFAAPPEKDLDWNEQGVD  628
                         AKMSKS  NVV+PD ++ +YGADT R++ +F +P +  + W+E+G++
Sbjct  596  FHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLE  655

Query  629  GCYRFLNRVWKLVHEQLEAVaaapaldpsalsdEERTLRRAVHKTLKKVTEDIDERFHFN  688
            G  +FL+RV +L+  +                ++  +L +  + T+K VTE++D+   FN
Sbjct  656  GSRKFLDRVYRLITTK------------EITEENSGALDKVYNETVKAVTEQVDQ-MKFN  702

Query  689  TAIAAVMELMNTLQGARLNTPQAAAVMKEALELVVIMLAPFVPHITEELWQ-LLGHTTPL  747
            TAIA +M ++N+       + +   +  +     V ++APF PH+ EELWQ L +   ++
Sbjct  703  TAIAQLMVFVNA-------ANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESI  755

Query  748  SATTWPAWDSeavldeellvvvqvNGKLRSKLSVAVGIDEEAIKQLALADDKVKVFTDGL  807
            S   WP+ D   ++++++ +VVQ++GK+++KL VA ++  E ++++ALA++KV+    G 
Sbjct  756  SYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGK  815

Query  808  QIRKVIYVPGKLVNIVV  824
            +I KVI VP KLVNIV+
Sbjct  816  DIIKVIAVPNKLVNIVI  832

1504) leuS in NC_000908


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  513 bits (1936),  Expect = 2e-146, Method: Compositional matrix adjust.
 Identities = 340/849 (41%), Positives = 543/849 (64%), Gaps = 78/849 (9%)

Query  2    YNHNLIEEKWLKKWKNKDVNRFESDSNKKKYYVLDMFPYPSAAGLHLGHVRAYTITDVIS  61
            Y+H  IE KW   W +++  +  +D++K K+Y LDMFPYPS+AGLH+GH  +YT TD++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  62   RYYKAKGFNVIHPIGFDAFGLPAEQYAINSNQNPGSWTDQNINNFINQLTSFGFDYDYHL  121
            R+ +A+G NV+HP+G DAFGLPAEQYA+++ ++P+  T +NI NF  Q+ ++GF YD + 
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  122  SLKTTDPRYYKYTQWIFSELFKANLAELVDIDVNWCEQLGTVLANEEVLIDSNGNAVSER  181
             ++TTDP YYK TQWIF+ L+   LA   ++ VNW E+LGT +ANEEVL D+     SER
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGT----SER  179

Query  182  GSFSVEKRKMKQWVLKITTFADALLEGLDTLDWPEPIKEMQRNWIGKSKGVTINFQLKDH  241
            G+++V ++ M+QW+LKIT++A+ LLE+L+ +DWPE+IK+MQRNWIGKS G  + F++KD 
Sbjct  180  GGYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDT  239

Query  242  KEAIAIFTTKPQTIFGVSFLAVSTNHWLAKKIAETNKKVASFlkkqlqktttlkqkATLY  301
               +++FTT+P+T+FG ++  ++ +H L   I+ +++  A    K+     +   ++ L 
Sbjct  240  DKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA  299

Query  302  -DGIDLLTN--AIHPLTNELIPVYVANYVIEGYGTDAIMGVGAHNENDNFFARKQKLKII  358
             +  ++ T   AI+P+    +PV +A+YV+ +YGT+AIM+V AH+E D  FA++ +L II
Sbjct  300  KEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDII  359

Query  359  NVIDKKERLQNSFAYNGLT---------TKEAQVAITNE-LISQNKAKLTTVYKLRDWIF  408
             V++  +  + +F+ +GL           K + +A   E L ++  ++    Y+LRDW+F
Sbjct  360  PVLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLF  419

Query  409  SRQRYWGEPFPIIF--DENNTPHlveqlpvelplleNYKPDGSGNSPLMRNQAWVNIVKD  466
            SRQRYWGEP+PII   D  +T+    +LP+ LP+  + +P G+G+SPL     W+++ ++
Sbjct  420  SRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRE  479

Query  467  N-IHYQRETNTMPQWAGSCWYYLGYLMLIKNPNFWPIDSKEAKKLFDQYLPVDLYVGGAE  525
            + +  +RETNTMPQWAGS WYYL Y+    +P+    +      L+ Q LPVD+YVGGAE
Sbjct  480  DGVKGRRETNTMPQWAGSSWYYLRYI----DPH--NTEKLADEELLKQWLPVDIYVGGAE  533

Query  526  HAVLHLLYARFWHKFLFDKKLVSTKEPFQKLINQGMVLGPD-------------------  566
            HAVLHLLYARFWHK L+D  +V+TKEPFQKL+NQGM+LG                     
Sbjct  534  HAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDG  593

Query  567  --------------GKKMSKSKGNTINPTPLVDSHGADALRLYLMFMGPISASLTWNDEG  612
                            KMSKS  N +NP  +V+  GAD+LR+Y MFMGP+ AS++W++EG
Sbjct  594  SFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEG  653

Query  613  LNGMRRWLDRVYNFFFNHAVVTDQVSQ-ETIFAYNLFLKNSYCHLDKHELNLVISEMMIF  671
            L+G R+ LDRVY ++    +  ++ +  + +  YN  +K    ++D+  +N  I+++M+F
Sbjct  654  LEGSRKFLDRVYRLITTKEITEENSGALDKV--YNETVKAVTEQVDQMKFNTAIAQLMVF  711

Query  672  LNFLYKTKKISLNYAKGFLTVLSFFAPFLAEELNEKCGLEPFVVKQAISLVDYQLFETAK  731
            +N   K  K+  +YAKGF+ +++ FAP L+EEL +  +L +    ++IS V    ++ +K
Sbjct  712  VNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ--ALTA--SGESISYVPWPSYDESK  767

Query  732  -----TKVILSINGKFKA----AKEFTKGSLEIDVLESFKQDKEINDILNQPIERVVYVQ  782
                   +++ I+GK KA    AK++++  L+   L +   +K   +I  + I +V+ V 
Sbjct  768  LVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALAN---EKVQAEIAGKDIIKVIAVP  824

Query  783  DRIINVLLK  791
            ++++N+++K
Sbjct  825  NKLVNIVIK  833

1505) MYSTI_05203 in NC_020126


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  513 bits (1934),  Expect = 2e-146, Method: Compositional matrix adjust.
 Identities = 348/862 (41%), Positives = 533/862 (62%), Gaps = 69/862 (8%)

Query  7    YEPQAIEGKWQARWDEAGIFRAGKRPGAPKKYVLEMLPYPSGK-MHMGHVRNYLIGDVYA  65
            Y+  AIE KWQA W +   F++G  ++ PK Y L+M+PYPSG  +H+GH   Y   D+ +
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  66   RYFLMRGYDVLHPMGWDAFGLPAENAAIKEGVHPAVRTAENIVSFKKEMKSLGYSYDWER  125
            R+   +G +VLHPMGWDAFGLPAE+ A+  G +PA  TAENI +FK+++++LG+SYDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  126  EVNTSAPEYYRWNQWFFIQMLERGLVYRRFSKVNWCTGCHTVIANEQV-KDGVCERCSSP  184
            EVNT+ P+YY+W QW+F ++ E+GL Y     VNW     T IANE+V  DG  ER + P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  185  VVDKEMPEWAFRITRFSQDLLSSLDTLKEWPDRITSMQRNWIGRSDGAEADFRVQGHDAS  244
            VV K M +W ++IT +++ LL  L+ + +WP+ I  MQRNWIG+S GA+  F+V++ D  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  245  LRVFTTRVDTIYGCTYVVLAPDHKLVAQVTTPERRAEVAAFVKRMAAQSKTERMGEGTEK  304
            + VFTTR DT++G TY VLAP+H LV  +TT+++   VA + ++ + +S   R + + EK
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEK  302

Query  305  EGIFTGAHAINPFTGQQVPIWIANFVLSDYGTGAVMSVPAHDERDFSFARKYALPVKVVI  364
             G+ TG+ AINP  G+++P+WIA++VL+ YGTGA+M+VPAHDERD  FA+++ L +  V 
Sbjct  303  TGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV-  361

Query  365  QPATGDKLPAGEALEAASTEYGVLVDSGEYTGKTSEVARQEMAKKLEQEGRGKATVTYRQ  424
                   L +G+  EAA TE G+ ++S+   G     A   M   LE EG G+  VTYR 
Sbjct  362  -------LEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRL  414

Query  425  KDWGFSRQRYWGTPIPIVYCEKCDPERQGIPVPVEQLPVRLPEIDVQEVLTGKGEPPLAK  484
            +DW FSRQRYWG PIPI+  E    +  + +VP  +LP+ LP +  +   +G GE+PLA+
Sbjct  415  RDWLFSRQRYWGEPIPIIHWE----DGTSTAVPESELPLVLP-VTKDIRPSGTGESPLAN  469

Query  485  VPSWVNTTCPKCGGPARREAETMDTFVDSCWYFARYLSPHYDAAPFDPKEAQRFLPVDIY  544
            V  W++ T    G  +RRE++TM    +S WY+ RY+ PH      D    ++ LPVDIY
Sbjct  470  VTDWLEVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIY  528

Query  545  VGGPEHAVMHLLYFRFWTRVMKLLGLSPVDEPVTRLITQGIVNGP---DGR---------  592
            VGG+EHAV+HLLY RFW +V+  LG+ P  EP  +L+ QG++ G    D+R         
Sbjct  529  VGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKV  588

Query  593  ---------------------KMSKRWGNVVAPASIVQKYGADTARAYVMFAGPPERDFD  631
                                 KMSK   NVV P  +V++YGADT R Y MF GP +  + 
Sbjct  589  EKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIA  648

Query  632  WSDDQVEGVFRFLKRVWTLasthhaavagathagPFEGKALEIRRAAHKGLKRVSEAIER  691
            WS++ +EG  +FL RV  L +T + +          E ++  + +  +  +K V+E +++
Sbjct  649  WSEEGLEGSRKFLDRVYRLITTKEIT----------EENSGALDKVYNETVKAVTEQVDQ  698

Query  692  LSFNTAIAGTMECVNALYATGTPETPAEKaamaeavrllaamlTPFAPHIADEIAEAYGS  751
            + FNTAIA  M  VNA        +  E    ++  + +  +++PFAPH+++E+ +A  +
Sbjct  699  MKFNTAIAQLMVFVNA--------ANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTA  750

Query  752  KELTVA-QAWPDFDPALVVDDVIPYAVQVNGKLRAEIQVPanaveadvraaaeadervqa  810
               +++  +WP +D + +V++ +   VQ++GK++A + V+ +    +++  A A+E+VQA
Sbjct  751  SGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQA  810

Query  811  aITGKTVRKFVFVPKRLVNFVV  832
             I+GK + K + VP++LVN+V+
Sbjct  811  EIAGKDIIKVIAVPNKLVNIVI  832

1506) Psest_0525 in NC_019936


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  513 bits (1935),  Expect = 2e-146, Method: Compositional matrix adjust.
 Identities = 357/875 (41%), Positives = 552/875 (64%), Gaps = 56/875 (6%)

Query  5    YQPREIEAAAQSHWDSQKSFEVSEQPGKDTFYCLSMFPYPSGK-LHMGHVRNYTIGDVIA  63
            Y+   IE+  Q+ W  + +F  + +++K  FY L MFPYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMQGKNVLQPMGWDAFGMPAENAAMKNQVAPAKWTYENIAYMKAQLKSLGLAVDWTR  123
            R++R QG NVL+PMGWDAFG+PAE+ AM     PA  T ENIA  K Q+++LG++ DW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVTTCKPDYYRWEQWLFTRLYQKGVIYRKNGTVNWDPVDQTVLANEQVI-DGRGWRSGAL  182
            EV T  P+YY+W QW+FT+LY+KG+ Y  +  VNW     T +ANE+V+ DG + R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  IEKREIPMYYFKITAYAdellesldeldGWPEQVKTMQRNWIGKSRGMEISFPYDIASIG  242
            + ++ +    +KITAYA E L    E  +WPE +K MQRNWIGKS G +++F       +
Sbjct  184  VVRKPMRQWMLKITAYA-ERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTF----KVKD  238

Query  243  SEGQMKVFTTRPDTLMGATYVAVAAEHPL-ATLAAQNDPELQAFIDECKRGGVAEADIA-  300
            ++ +  VFTTRPDTL GATY  +A+EH+L  ++++ +++E    + + KR +   +D+A 
Sbjct  239  TDKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEA---VADYKRQASLKSDLAR  295

Query  301  ---TQEKKGLATSLRVQHPLTGELLPVWVANYVLMNYGEGAVMAVPAHDERDFEFASKYG  357
               ++EK G+ T+    +P+ G  +PVW+A+YVL +YG GA+MAVPAHDERD EFA ++ 
Sbjct  296  TDLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFN  355

Query  358  LPIKPVVRTSAGDLTPSPWQDAYGEHGELINSGIFDGLDFAGAFDAIEVALQKKGLGQAR  417
            L I PV+  +  +      + A+ E+G  INS+++DGLD A+A+  +   L+  G+G+  
Sbjct  356  LDIIPVLEGGNVE------EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNEN  409

Query  418  TQFRLRDWGISRQRYWGCPIPIIHCDSCGDVPVPEDQLPVVLP--ENVVPDGAG-SPLAR  474
              +RLRDW +SRQRYWG PIPIIH +     +VPE +LP+VLP   ++ P G+G SPLA 
Sbjct  410  VTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLAN  469

Query  475  MPEFYECSCPKCGAPAKRETDTMDTFVESSWYFARYASPNYDQGMVDPAAANHWLPVDQY  534
            + +  E +    G  ++RET+TM     SSWY+ RY  P+  + + D    ++WLPVD Y
Sbjct  470  VTDWLEVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIY  528

Query  535  IGGIEHAILHLLYARFFHKLMRDEGLVSSNEPFKNLLTQGMVVADTYYRTLENGGKDWFN  594
            +GG EHA+LHLLYARF HK++ D G+V+++EPF++L+ QGM+++ + YR          +
Sbjct  529  VGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS-YR----------D  577

Query  595  PADVIVERDAKAKVIGAKLASDGLPVEIGGTEKMSKSKNNGVDPQAMIDAYGADTCRLFM  654
            + + +V  D   K  G+ +  +       +  KMSKS +N V+P+ +++ YGADT R++ 
Sbjct  578  SRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYE  637

Query  655  MFASPPDMSLEWSDSGVEGASRFLRRVWRLghahisagaagaLDTASLSDEQKAVRRAIH  714
            MF +P D S+ WS+ G+EG+ +FL RV RL            + T  +++E+ +    + 
Sbjct  638  MFMGPLDASIAWSEEGLEGSRKFLDRVYRL------------ITTKEITEENSGALDKVY  685

Query  715  LAIKQASVDVGQHHKFNTAIAQVMTLMNVLEKAATATEQDRALLQEGLETVALLLAPITP  774
                +A  +  ++ KFNTAIAQ+M ++N       A++++  L+ +       L+AP++P
Sbjct  686  NETVKAVTEQVDQMKFNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAP  738

Query  775  HISHELWQQLGKPGAIID-ASWPKVDESALVQDSLTLVVQVNGKLRGQIevaaaatreev  833
            H+++ELWQ L  +G  I   +WP  DES LV++ + +VVQ++GK+++++ VA   +REE+
Sbjct  739  HLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREEL  798

Query  834  eaaarSNENVLRFTEGLTIRKVIVVPGKLVNIVAN  868
            +  A +NE+V     G  I KVI VP KLVNIV +
Sbjct  799  QEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

1507) leuS in NC_007940


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  513 bits (1934),  Expect = 2e-146, Method: Compositional matrix adjust.
 Identities = 324/805 (41%), Positives = 527/805 (66%), Gaps = 29/805 (3%)

Query  16   AFEVPNESSKPKYYVLEMLPYPSGK-IHVGHVRNYSIGDVVARFMTMQGFNVLHPMGWDS  74
            +F    ++SKPK+Y L+M+PYPSG  +HVGH   Y+  D+++RF   QG NVLHPMGWD+
Sbjct  22   TFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSRFKRAQGHNVLHPMGWDA  81

Query  75   FGLPAENAAIKNNSHPKEWTYSNIENMKKQLKSMGFSYDWSREINSCDPDYYKHEQKFFL  134
            FGLPAE+ A+   ++P E T  NI N K+Q++++GFSYDW RE+N+ DP+YYK  Q +F 
Sbjct  82   FGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFT  141

Query  135  ELYERNLAYQKESLVNWDPVDNTVLANEQVV-DGRGWRSGAIVEKRYLKQWFLKITNYAE  193
             LYE+ LAY+ E  VNW     T +ANE+V+ DG + R+G  V ++ ++QW LKIT YAE
Sbjct  142  KLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAE  201

Query  194  ELLNEIPNLTEWPEAVRSMQEKWIGKSVGANFRFKIKDNEDVIEVFSTKPETIFGASFVG  253
             LL+++ ++ +WPE+++ MQ +WIGKS GAN  FK+KD +  + VF+T+P+T+FGA++  
Sbjct  202  RLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAV  260

Query  254  IAFNHPIIEKLVS--KTPEIENFIAKCS--NITGSAEFDKAEKEGIFTGLYVVHPFDSNI  309
            +A +H++++ + +  ++  + ++  + S  +  + +++ K EK G+ TG Y ++P +++ 
Sbjct  261  LAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK-EKTGVWTGSYAINPVNGK-  318

Query  310  TLPVVITNFVLMDYGTGAVFGCPAHDQRDHELAVKINLPIKQVIEADTDVQKAAYTEDGI  369
             +PV I+++VL  YGTGA+ + PAHD+RD E+A ++NL I  V+E++ +V+ AA+TEDG+
Sbjct  319  EMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGG-NVEEAAFTEDGL  377

Query  370  IINSGFLNGLSTNEAKQRVIEEFEKLGIGKRTINYRLKDWGISRQRFWGCPIPIIHCDSC  429
             INS+FL+GL    A  +++E +E  G+G+  + YRL+DW +SRQR+WG PIPIIH +  
Sbjct  378  HINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDG  437

Query  430  GLVPVPDSDLPVTLP--DDVKFDGHGN-PLDNHPTWKHVNCPKCSKPAIRETDTFDTFFE  486
               +VP+S+LP+ LP   D++  G G+ PL N   W +V      K + RET+T      
Sbjct  438  TSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVK-GRRETNTMPQWAG  496

Query  487  SSWYFTRYCNSQALE-MTDKKACDYWLPVDKYIGGIEHAVMHLLYARFFTKVMNEQDYVS  545
            SSWY+ RY +++  E ++D      WLPVD Y+GG EHAV+HLLYARF  KV+ + + V+
Sbjct  497  SSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVP  556

Query  546  VREPFKGLFTQGMVLHATYKDEHNNWLYPEEVIKKGNEFFHKENGGLVTQGRIEKMSKSK  605
             +EPF+ LF QGM+L ++Y+D +   +  + V K++  FFH E G  + Q+   KMSKS 
Sbjct  557  TKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEELEQAP-AKMSKSL  615

Query  606  KNLIDLETMQQQYGADAIRFFVLSDSPPEKDLEWSASGIEGSARFINKLEQMQETIIKLS  665
            KN+++ + + +QYGAD++R + +  +P +  + WS  G+EGS +F++++ ++   I    
Sbjct  616  KNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRL---ITTKE  672

Query  666  DNKNTNKELKRLIHFTIKHVAEDIKHFALNRAIARMRELFNAISSEINKEEIDVQNAKHG  725
               + +  L ++ + T+K V+E++ +  +N AIA++  + NA     NKE+    +   G
Sbjct  673  ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNA----ANKEDKLFSDYAKG  728

Query  726  FNVLIQLLNPFIPHITEEIWQKL--GHKTFLYNAAFPTFDESMLELDTYVIAVQVNGKLR  783
            F   +QL+ PF PH+ EE+WQ L  +  ++ Y  + P++DES L  +   I VQ++GK++
Sbjct  729  F---VQLIAPFAPHLGEELWQALTASGESISY-VPWPSYDESKLVENDVEIVVQIKGKVK  784

Query  784  DTYEFNTSASEDEIKQIAINLPKVQ  808
                     S +E++++A+   KVQ
Sbjct  785  AKLVVAKDLSREELQEVALANEKVQ  809

1508) Gbro_4829 in NC_013441


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  513 bits (1934),  Expect = 3e-146, Method: Compositional matrix adjust.
 Identities = 357/736 (49%), Positives = 490/736 (67%), Gaps = 60/736 (8%)

Query  223  LVYQSDSLVNWCPGLGTVLANEEVTADGRSDRGNFPVFRKHLRQWMMRITAYSdrllddl  282
            L Y+++  VNW   LGT +ANEEV +DG S+RG +PV RK +RQWM++ITAY++RLL+DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  283  dlldWPEKVKTMQRNWIGRSRGAQVAFPVPGTDHLIEVFTTRPDTLFGATYMVLSPEHPL  342
            + +DWPE +K MQRNWIG+S GA+V+F V +TD  + VFTTRPDTLFGATY VL+PEH+L
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  343  VDDLTAAAWPDGVDSRWTAGATSPadavkayraaiaaKSDLERQE-NKQKTGVFTGTYAT  401
            VD +T++  +++V                 Y+   + KSDL R +  K+KTGV TG+YA 
Sbjct  268  VDAITTSDQAEAVAD---------------YKRQASLKSDLARTDLAKEKTGVWTGSYAI  312

Query  402  NPVNGEQIPVFIADYVLMGYGTGAIMAVPAHDGRDYEFATVFGLPIVEVIGSEQGVATEA  461
            NPVNG ++PV IADYVL +YGTGAIMAVPAHD RD EFA  F L I+ V+ + + V   A
Sbjct  313  NPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGN-VEEAA  371

Query  462  FTGDGPLVNSSFLDGLAVDDAKARIISWLEEQGKGTGTVQYKLRDWLFARQRYWGEPFPI  521
            FT DG  +NS FLDGL    A A+++ WLE +G G   V Y+LRDWLF+RQRYWGEP+PI
Sbjct  372  FTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPI  431

Query  522  VYDADGNAHALPESMLPVELPEVDDYapvsfdpddadsdpspplaKATDWMTVELDLGDG  581
            +   DG + A+PES LP+ LP   D          + +   +PLA+ TDW+ V  +  DG
Sbjct  432  IHWEDGTSTAVPESELPLVLPVTKD--------IRPSGTGESPLANVTDWLEVTRE--DG  481

Query  582  VQTYTRDANVMPQWAGSSWYQLRYIDPTNAEEFCAKENEAYWMGPRPALHGPDDPGGLDL  641
            V+   R++N MPQWAGSSWY LRYIDP N+E +   E    W+              +D+
Sbjct  482  VKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWL-------------PVDI  527

Query  642  YIGGVEHAVLHLLYSRFWHKVLFDLGYVTSREPYRKLFNQGMIQAYAYTDSRGIYVPADE  701
            Y+GG EHAVLHLLY+RFWHKVL+DLG V ++EP++KLFNQGMI + +Y DSRG  V++D 
Sbjct  528  YVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDK  587

Query  702  VTERDGAYFH--NGEPVRQEYGKMGKSLKNSVAPDDICRDYGADTLRVYEMFMGPLDQSR  759
            V  RDG++FH   GE + Q  +KM+KSLKN V PDD+  +YGADTLRVYEMFMGPLD S 
Sbjct  588  VEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASI  647

Query  760  PWATKDVVGSQRFLQRIWRLVVDEETGALRVSEAEPDDETKRVLHKTIAGVREDYDALRN  819
            +W+  ++ GS++FL+R+ RL+   E         E  +   +V + T+ +V E+ D ++ 
Sbjct  648  AWSEEGLEGSRKFLDRVYRLITTKEIT------EENSGALDKVYNETVKAVTEQVDQMKF  701

Query  820  NTAVAKLTVLTNHLTKN---FESTGAPRAAVEPLVIMLAPLAPHIAEELWGRL-GHGEML  875
            NTA+A+L V+ N   K+   F   +        +V ++AP+APH++EELW  L + GE +
Sbjct  702  NTAIAQLMVFVNAANKEDKLFSDYA------KGFVQLIAPFAPHLGEELWQALTASGESI  755

Query  876  VRGPFPDPDPQWLLEDTIEIPIQVKGKVRSRIQVAADADEATIREAALADEKIAALLDG-  934
               P P  D   L+E+ +EI +Q+KGKV++++ VA D     ++E ALA+EK+ A + G 
Sbjct  756  SYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGK  815

Query  935  EPRKVIVVPGRMVNVV  950
            +  KVI VP ++VN+V
Sbjct  816  DIIKVIAVPNKLVNIV  831


 Score =  129 bits (474),  Expect = 7e-31, Method: Compositional matrix adjust.
 Identities = 71/155 (46%), Positives = 100/155 (65%), Gaps = 16/155 (10%)

Query  19   GDIERRWQQLWSERHAYEAPNPVGPLAGDLSAFDGGGPQAADKLFVQDMFPYPSGAGLHV  78
              IE +WQ +W++ H+                F  G   +  K++  DMFPYPSGAGLHV
Sbjct  7    TAIEPKWQAFWADNHT----------------FKTGTDASKPKFYALDMFPYPSGAGLHV  50

Query  79   GHPLGFIASDVFARYQRMTGRNVLHTMGFDSFGLPAEQYAVQTGTHPRTTTEANIERYLA  138
            GHP G+ A+D+++R++R  G+NVLH MG D+FGLPAEQYA++TG +P   T  NI  +  
Sbjct  51   GHPEGYTATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKR  110

Query  139  QIRQLGLGHDERRRVATTDVEFYRWTQWIFLQIYN  173
            QI  LG++ D  R V TTD ++Y+WTQWIF ++Y+
Sbjct  111  QINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1509) leuS in NC_009480


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  512 bits (1933),  Expect = 3e-146, Method: Compositional matrix adjust.
 Identities = 351/873 (41%), Positives = 515/873 (59%), Gaps = 83/873 (9%)

Query  13   YDFRAIEAEWSEVWEREQPFRTPDASDSRPRKYILDMFPYPSG-DLHMGHAEAFALGDAV  71
            YD  AIE+ W   W  ++ F+T ++  S+P+ Y LDMFPYPSG +LH+GH+E+++  D +
Sbjct  4    YDHTAIEPKWQAFWADNHTFKT-GTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDIL  62

Query  72   ARYWRQQGFNVLHPIGWDSFGLPAENAAIKRGVDPREWTYANIETQKQSMKRYGLSFDWE  131
            +R+ R QG NVLHP+GWD+FGLPAE+ A+  G DP E T  NI   K+ ++  G+S+DW+
Sbjct  63   SRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWD  122

Query  132  RELHTSDPEYYRWNQWLFLKMHEKGLAYRKDSWVNWDPVDQTVLANEQVLPDGTSDRSGA  191
            RE++T+DP+YY+W QW+F K+ EKGLAY  +  VNW     T +ANE+VLPDGTS+R+G 
Sbjct  123  REVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGY  182

Query  192  VVVKKKLTQWYLRITDYADRLVDDLNQLEGTWPAKVISMQRNWIGRSIGAEVDFVVEGRD  251
             VV+K + QW L+IT YA+RL++DL++++  WP  +  MQRNWIG+S GA+V F V + D
Sbjct  183  PVVRKPMRQWMLKITAYAERLLEDLEEVD--WPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  252  EPVTVFTTRPDTLHGATFMVVAPDSDLAAELVEGASDEVRERFRGYLERTQRLN-EIERS  310
               TVFTTRPDTL GAT+ V+AP+  L   +  +   E    ++    R   L+ ++ R+
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYK----RQASLKSDLART  296

Query  311  TTDRPKTGIPLGRTAINPVNGERIPVWAADYLLADYGTGAVMAVPAHDQRDLDFARAFDL  370
               + KTG+  G  AINPVNG  +PVW ADY+LA YGTGA+MAVPAHD+RD +FA+ F+L
Sbjct  297  DLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNL  356

Query  371  PVRVVVDTTQPVTGAIRIIPEDGELPDLEEVLPGRTGVALPGEGRLINSGSLNGLSKQPA  430
             +  V+              E+G++ +           A+  +G  INS+ L+GL K +A
Sbjct  357  DIIPVL--------------EGGNVEE----------AAFTEDGLHINSDFLDGLDKASA  392

Query  431  IKRVIEQLEAEGRGRAAKNYRLRDWLISRQRFWGTPIPIVYDAEGNEIRVPEDQLPVRLP  490
            I +++E LEAEG G     YRLRDWL+SRQR+WG PIPI+   +G    VPE +LP+ LP
Sbjct  393  IAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLP  452

Query  491  DTEGLDLAPKGKSPLAAATEWTNVPSPVDGSPATRDPDTMDTFMDSSWYWLRFLSPNDAT  550
             T ++  +  G SPLA  T+W +V    DG  + R+ +TM    +SSWY LR++ P+++ 
Sbjct  453  VTKDIRPSGTGESPLANVTDWLEVTRE-DGVKGRRETNTMPQWAGSSWYYLRYIDPHNTE  511

Query  551  KAFDPADADRWAPIDQYVGGVEHAILHLLYSRFITKVLFDLGYVTFTEPFSALLNQGMVL  610
            K  D     +W P+D YVGG EHA+LHLLY+RF  KVL+DLG V   EPF  L+NQGM+L
Sbjct  512  KLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMIL  571

Query  611  sggskmskskg--------------gVDLGSEMD---------------------RHGVD  635
            + + + S++                 V+ G E++                     + G D
Sbjct  572  GTSYRDSRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGAD  631

Query  636  AIRLTMAFAGPPEDDIDWEDVSPSGSAKFLARAWRLTGDITSAPEIEWKTGDEALRRVTH  695
            ++R+   F GP +  I W + +  GS KFL R  RL      + E        AL +V +
Sbjct  632  TLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITEE-----NSGALDKVYN  686

Query  696  RFLAEAPGMLEAFKFNVVIARTMELVNAIRKTIDQGPGGGDAAVREATEVVAIALSLFAP  755
              +      ++  KFN  IA+ M +VNA  K         D    + +      ++ FAP
Sbjct  687  ETVKAVTEQVDQMKFNTAIAQLMVFVNAANK--------EDKLFSDYAKGFVQLIAPFAP  738

Query  756  YTAEDMWRRLGREG-SVAFAGWRKAERNLLVQSTVTAVVQVDGKVRDKLEVDAKIGADEL  814
              +E++W+ L   G S+++  W   + + LV++ V  VVQ+ GKV+ KL V   ++ +EL
Sbjct  739  HLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREEL  798

Query  815  EALARETAGVKRSTAGRTIDKVIVRAPKIVSIT  847
            + +A     V+   AG+ I KVI  + K+V+I 
Sbjct  799  QEVALANEKVQAEIAGKDIIKVIAVPNKLVNIV  831

1510) leuS in NC_012704


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  512 bits (1933),  Expect = 4e-146, Method: Compositional matrix adjust.
 Identities = 353/761 (47%), Positives = 495/761 (66%), Gaps = 78/761 (10%)

Query  282   LVYRSRSTVNWAPGLGTVLANEEVTADGRSERGNFPVFRKKLTQWMMRITQYSdrllddl  341
             L Y +   VNW   LGT +ANEEV +DG SERG +PV RK + QWM++IT Y++RLL+DL
Sbjct  148   LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  342   dlldWPDKVKSMQRNWIGRSRGAEVTFAIPTNTSSHDAAQCPVFTTRPDTLFGAEYLVLA  401
             + +DWP+ +K MQRNWIG+S GA+VTF +      +   +  VFTTRPDTLFGA Y VLA
Sbjct  208   EEVDWPESIKDMQRNWIGKSTGANVTFKV-----KDTDKDFTVFTTRPDTLFGATYAVLA  262

Query  402   PEHELVDEIVADQWPDLRAERSLSDDAIDRWTSGAATPAEAVKEYRASIVAKSDLERQE-  460
             PEH LVD I + +                         AEAV +Y+     KSDL R + 
Sbjct  263   PEHALVDAITTSD------------------------QAEAVADYKRQASLKSDLARTDL  298

Query  461   NKEKTGVFLGVYATNPVNGRRIPVFIADYVLSGYGTGAIMAVPAHDERDYDFARVFELPI  520
              KEKTGV  G YA NPVNG+ +PV IADYVL++YGTGAIMAVPAHDERD +FA+ F+L I
Sbjct  299   AKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDI  358

Query  521   TEVISGGDVTVEAFTGAGTAVNSANDDGLDINGLHLEDAKARTIDWLAQRGVGKEKIQYK  580
               V+ GG+V   AFT  G  +NS   DGLD  +     A A+ ++WL   GVG+E++ Y+
Sbjct  359   IPVLEGGNVEEAAFTEDGLHINSDFLDGLDKAS-----AIAKMVEWLEAEGVGNENVTYR  413

Query  581   LRDWLFARQRYWGEPFPVVYDENDVAHPLPESMLPVVLPDVDDYRPVSFDPDDAESEPHP  640
             LRDWLF+RQRYWGEP+P++  E++ + ++PES LP+VLP   D RP         +  ++
Sbjct  414   LRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGES  465

Query  641   PLAKAKDWVNVELDLGDGPKKYRRDTNVMPQWAGSSWYELRYVDPTNQDALCDPENEKYW  700
             PLA+  DW++V  +  DG K  RR+TN MPQWAGSSWY LRY+DP N + L D E  K W
Sbjct  466   PLANVTDWLEVTRE--DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQW  522

Query  701   MGPTDQKKSGGVDLYVGGVEHAVLHLLYSRFWHKVLFDLGYVSSCEPYHRLFNQGYIQAF  760
             +          VD+YVGG EHAVLHLLY+RFWHKVL+DLG V++ EP+++LFNQG I + 
Sbjct  523   L---------PVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGT  573

Query  761   AYTDDRGVYIPAAEVVERDGSFWWVPSDGRNMDGVQTNEHGEIQVHQEYGKMGKSLKNAV  820
             +Y D RG  +++  V  RDGSF            V+T E    +++Q  +KM+KSLKN V
Sbjct  574   SYRDSRGALVATDKVEKRDGSFF----------HVETGE----ELEQAPAKMSKSLKNVV  619

Query  821   SPEDICDNYGADTLRIYEMSMGPLDTSRPWATKDVVGSQRFLQRLWRLVVDESTGdlvvt  880
             +P+D+ ++YGADTLR+YEM MGPLD+S +W+  ++ GS++FL+R+ RL+           
Sbjct  620   NPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEIT-----  674

Query  881   datptdddrralHRTIVAVREDYAQLMDNTAVAKLIEYVNYVTKTYAGGAPREIVEPAVL  940
                 ++   +  + T+ AV E+  Q+  NTA+A+L+ +VN   K   +    +     V 
Sbjct  675   -EENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANK--EDKLFSDYAKGFVQ  731

Query  941   LVAPLAPHIAEELWSRL-GHTESLAHGPFPTFEEKWLVDDTVEIPVQVQGKVRSRINVAT  999
             L+AP+APH++EELW  L +  ES++  P P+++E  LV++ VEI VQ++GKV++++ VA 
Sbjct  732   LIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAK  791

Query  1000  DASREDIEAAALDDAKVKEHVGDHEIKKVIVVPGRMVNVVI  1040
             D SRE+++  AL + KV+ ++++ +I KVI VP ++VN+VI
Sbjct  792   DLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832


 Score =  128 bits (469),  Expect = 2e-30, Method: Compositional matrix adjust.
 Identities = 73/152 (49%), Positives = 101/152 (67%), Gaps = 12/152 (7%)

Query  57   AEIENAWHERWSDEGTFNAPNPTGDLAPRDGGSDLPDDRIFVQDMFPYPSGVGLHVGHPL  116
            + IE  W+  W+D+ TF++            G+D +  +++  DMFPYPSG GLHVGHP 
Sbjct  7    TAIEPKWQAFWADNHTFKT------------GTDASKPKFYALDMFPYPSGAGLHVGHPE  54

Query  117  GYIATDVYARFHRMLGKNVLHTLGYDAYGLPAEQYAVQTGTHPRTTTEANIANMKRQLGR  176
            GY ATD+ +RF R  G NVLH +G DA+GLPAEQYA++TG +P   T  NIAN KRQ+  
Sbjct  55   GYTATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINA  114

Query  177  LGLGHDPRRSFATTDQDFYRWTQWIFLQIFNS  208
            LG++ D  R   TTD ++Y+WTQWIF ++++ 
Sbjct  115  LGFSYDWDREVNTTDPNYYKWTQWIFTKLYEK  146

1511) leuS in NC_008699


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  512 bits (1931),  Expect = 4e-146, Method: Compositional matrix adjust.
 Identities = 344/858 (41%), Positives = 519/858 (61%), Gaps = 70/858 (8%)

Query  32   YDVRAIQDKWLPVWERLDPFRADDSSPREKKYALTMFPYPSG-DLHMGHAEVTALHDVVA  90
            YD  AI+ KW + W   + F+++  +++ K YAL MFPYPSG +LH+GH+E  +  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  91   RYWWQRGYEVLNPMGWDSFGLPAENAAIRNDEHPATYTYANIETQYESFKR----YAVSF  146
            R+ + +G +VL+PMGWD+FGLPAE+ A+  +++PA +T  NI     +FKR     + S+
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIA----NFKRQINALGFSY  119

Query  147  DWSRRLHTSDPEYYRWTQWLFLKFRERGLAYRKSSPVNWCPNDQTVLANEQVV-DGRCER  205
            DW R ++T+DP+YY+WTQW+F K+ E+GLAY    PVNW  +  T +ANE+V+ DG  ER
Sbjct  120  DWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSER  179

Query  206  CGAEVTKRELTQWYFKITDYAQELLDRLDDLEPTWPARVVTAQRNWIGRSEGAHVDFVVD  265
             G  V ++ + QW +KIT YA+ LL+ L++++  WP  +   QRNWIG+S GA+V F V 
Sbjct  180  GGYPVVRKPMRQWMLKITAYAERLLEDLEEVD--WPESIKDMQRNWIGKSTGANVTFKVK  237

Query  266  GRDEPITVYTTRPDTIFGTTFMVVAVDSPLAAELVTDAQRPAFEAYreeirketeierLS  325
            + D  +TV+TTRPDT+FG+T+ V+A + +L   + T  Q  A   Y+ +    +++ R  
Sbjct  238  DTDKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTD  297

Query  326  TDRPKTGVDLGVTATNPVTGTQIPVWATDYVLADYGTGAVMGVPGGDQRDWEFATEMGLD  385
              + KTGV  G  A NPV G ++PVW +DYVLA YGTGA+M+VP+ D+RDWEFA +  LD
Sbjct  298  LAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLD  357

Query  386  IVRTTQTPEGFDGEAYHGEGPAINSPAPGADAPLDINGLPVDEAKRATIEFLEQQGTGAG  445
            I+   +  +  +  A+  +G  INS          ++GL    A    +E LE +G G  
Sbjct  358  IIPVLEGGNV-EEAAFTEDGLHINSDF--------LDGLDKASAIAKMVEWLEAEGVGNE  408

Query  446  AVNFRLRDWLLSRQRYWGVPIPIIHCDACGEVAVPYDQLPLELPELRGADLKPKGVSPLA  505
             V +RLRDWL+SRQRYWG PIPIIH +     AVP  +LPL LP  ++      G SPLA
Sbjct  409  NVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLA  468

Query  506  AAEEWVNVACPECGGAATRDSDTMDTFVDSSWYFLRYCSPDYTEGPFDVEKAKAWMPADI  565
               +W++V+  + G  + R+++TM    +SSWY+LRY  P+ TE   D E  K W+P DI
Sbjct  469  NVTDWLEVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDI  527

Query  566  YVGGVEHAVLHLLYARFFTKVLRDMGMLEVDEPFAAQLNQGIVINQG-------------  612
            YVGG EHAVLHLLYARF  KVL D+G++   EPF   +NQG+++  +             
Sbjct  528  YVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDK  587

Query  613  ---------------------KKMSKSLGNGVSLGDQLAEFGVDAVRVTLVFAGPPEDDI  651
                                  KMSKSL N V+ +D + ++G D++RV  +F GP +  I
Sbjct  588  VEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASI  647

Query  652  DWADVSPAGALRFLQRAWRLSGDVTSEAGTPAAGGDVALRRVTARTVHDAAELIESYRFN  711
             W++ +  G+ +FL+R  RL   +T+   T   +G  AL +V   TV   +E ++  +FN
Sbjct  648  AWSEEGLEGSRKFLDRVYRL---ITTKEITEENSG--ALDKVYNETVKAVTEQVDQMKFN  702

Query  712  VMVARVMELVNATRKAIdgapgpadpaVREATETVAILLSLVAPYVAEEMWERL-GHEPT  770
              +A++M +VNA+ K         D    + +     L++  AP ++EE+W+ L +   +
Sbjct  703  TAIAQLMVFVNAANKE--------DKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGES  754

Query  771  VARVGWPEVDPALLVEEQVTAVVQIQGKVRARLEVAPDISEADLEQLAMADPAVVRAIDG  830
            ++ V WP  D + LVE++V  VVQI+GKV+A+L VA D+S  +L+++A+A+  V   I G
Sbjct  755  ISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAG  814

Query  831  RPVRKVIVRAPKLVNVVV  848
            + + KVI  + KLVN+V+
Sbjct  815  KDIIKVIAVPNKLVNIVI  832

1512) leuS in NC_021663


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  511 bits (1926),  Expect = 1e-145, Method: Compositional matrix adjust.
 Identities = 355/749 (48%), Positives = 503/749 (68%), Gaps = 64/749 (8%)

Query  210  EHRLVYRSNSTVNWCPGLGTVLANEEVTADGRSERGNFPVFRKRLSQWMMRITAYSDRLI  269
            E  L Y ++  VNW   LGT +ANEEV +DG SERG +PV RK + QWM++ITAY++RL+
Sbjct  145  EKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLL  204

Query  270  DDLADLDWPEKVKAMQRNWIGRSRGAEVDFSAALSAPKTEARIRVFTTRPDTLFGASYMV  329
            +DL ++DWPE +K MQRNWIG+S GA+V F        T+  + VFTTRPDTLFGA+Y V
Sbjct  205  EDLEEVDWPESIKDMQRNWIGKSTGANVTFKVK----DTDKDFTVFTTRPDTLFGATYAV  260

Query  330  LAPEHELVDALVPAGDYPAGTDPRWTNGEaspaaavaayrtaiaaKSDLERQE-NKEKTG  388
            LAPEH LVDA+  +++  A +D ++  +                 KSDL R +  KEKTG
Sbjct  261  LAPEHALVDAITTSDQAEAVADYKRQAS----------------LKSDLARTDLAKEKTG  304

Query  389  VFTGAYATNPVNGAQIPVFIADYVLTGYGTGAIMAVPAHDDRDHEFATVFGLPITEVVSG  448
            V TG+YA NPVNG ++PV IADYVL++YGTGAIMAVPAHD+RD EFA  F L I  V+ G
Sbjct  305  VWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEG  364

Query  449  GDDVQDAAWTGDGVLVNSANDAGLDLNGLDKQQAIEATIAWLAGQGVGEEKIQYKLRDWL  508
            G +V++AA T DG+ +NS       L+GLDK  AI   + WL ++GVG+E++ Y+LRDWL
Sbjct  365  G-NVEEAAFTEDGLHINSDF-----LDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWL  418

Query  509  FARQRYWGEPFPVVYDADGVAHALPESMLPVELPEVEDYKPVsfdpddaasepspplaKA  568
            F+RQRYWGEP+P++   DG + A+PES LP+ LP   D +P        ++   +PLA+ 
Sbjct  419  FSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANV  470

Query  569  KDWVEVTLDLGDGEQTYWRDTNVMPQWAGSSWYQLRYIDPTNSEQFVDLANERYWTGPRE  628
             DW+EVT + G   +   R+TN MPQWAGSSWY LRYIDP N+E++ D    + W     
Sbjct  471  TDWLEVTREDGVKGR---RETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQW-----  522

Query  629  GMPSGGVDLYVGGVEHAVLHLLYSRFWHKVLFDLGYVSSYEPYHRLYNQGYIQAYAYTDA  688
             +P   VD+YVGG EHAVLHLLY+RFWHKVL+DLG V++ EP+++L+NQG I + +Y D+
Sbjct  523  -LP---VDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDS  578

Query  689  RGVYVPAAEVEEKDGKFYY--DGEEVNQEYGKMGKSLKNAVSPDEICDNYGADTLRVYEM  746
            RG  V++  VE +DG F+    GEE++Q  +KM+KSLKN V+PD++ ++YGADTLRVYEM
Sbjct  579  RGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEM  638

Query  747  SMGPLDTSRPWATKDVVGAQRFLQRAWRLAVNEETGDAAVSEAVLTDDDLRALHRTVAGV  806
             MGPLD+S +W+  ++ G+++FL+R  RL    E  +   + + L     +  + TV +V
Sbjct  639  FMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITEE--NSGALD----KVYNETVKAV  692

Query  807  TDDYANLRDNTAVAKLIEYVNYLTKayagqggaagaapraaVEPLALMLAPVAPHIAEEM  866
            T++  +++ NTA+A+L+ +VN   K         +         +  ++AP APH++EE+
Sbjct  693  TEQVDQMKFNTAIAQLMVFVNAANK--------EDKLFSDYAKGFVQLIAPFAPHLGEEL  744

Query  867  WSRLGHSG-SLAHADFPTYEETWLVDDTVELPVQVMGKVRGRVTVPadasreaieaaala  925
            W  L  SG S++    P+Y+E+ LV++ VE+ VQ+ GKV++++ V+ D SRE ++  ALA
Sbjct  745  WQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALA  804

Query  926  ePNVQAHIEGKTVAKIIVVPGKMVNIVAK  954
            + +VQA+I GK + K+I VP K+VNIV K
Sbjct  805  NEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833


 Score =  121 bits (441),  Expect = 3e-28, Method: Compositional matrix adjust.
 Identities = 78/150 (52%), Positives = 104/150 (70%), Gaps = 10/150 (6%)

Query  18   GDIEARWQNHWREQGTFNAPNPVGDLAEPGTELSEDKLFVQDMFPYPSGVGLHVGHPLGY  77
              IE++WQ  W ++ TF++          GT+ S  K++  DMFPYPSG GLHVGHP GY
Sbjct  7    TAIEPKWQAFWADNHTFKT----------GTDASKPKFYALDMFPYPSGAGLHVGHPEGY  56

Query  78   IATDVFARFHRMQGRNVLHTLGYDAFGLPAEQYAVQTGTHPRTTTQANIDNMErqlgrlg  137
             ATD+++RF R QG+NVLH +G DAFGLPAEQYA++TG +P   T  NI N  RQ+  LG
Sbjct  57   TATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALG  116

Query  138  lghdrrrVVATTDTDFYRWTQWIFLKIYNS  167
            ++ D+ R V TTD ++Y+WTQWIF K+Y+ 
Sbjct  117  FSYDWDREVNTTDPNYYKWTQWIFTKLYEK  146

1513) Micau_4485 in NC_014391


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  511 bits (1927),  Expect = 1e-145, Method: Compositional matrix adjust.
 Identities = 347/735 (48%), Positives = 493/735 (68%), Gaps = 55/735 (7%)

Query  218  DHRLAYVSEAPVNWCPGLGTVLANEEVTADGRSERGNFPVFKRNLKQWMMRITAYGDRLL  277
            +  LAY +E PVNW   LGT +ANEEV +DG SERG +PV ++ ++QWM++ITAY++RLL
Sbjct  145  EKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLL  204

Query  278  EDLDTLDWPEPIKLQQRNWIGRSTGAHIDFPTDAA--PVRVFTTRPDTVFGATYMVLAPE  335
            EDL+ +DWPE+IK  QRNWIG+STGA++ F    +     VFTTRPDT+FGATY VLAPE
Sbjct  205  EDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPE  264

Query  336  HELVDVLTPAAWPEGTRDAWTGGHAGPreaveayrkaaaakTDVERQADSKEKTGVFVGA  395
            H LVD +T +  +E+  D               Y++ A+ K+D+ R   +KEKTGV  G+
Sbjct  265  HALVDAITTSDQAEAVAD---------------YKRQASLKSDLARTDLAKEKTGVWTGS  309

Query  396  YATNPVTGGQIPIFIADYVLAGYGTGAIMAVPAQDERDWDFAEVFELPIVRTVQPPEGFD  455
            YA NPV G ++P+ IADYVLA+YGTGAIMAVPA+DERDW+FA  F+L I+  ++  +  +
Sbjct  310  YAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNV-E  368

Query  456  GKAYTGDGPAINSAAPERGIDLDGLGVTDAKARIIEWLEANGHGAGAVTWRLRDWLFSRQ  515
              A+T DG  INS        LDGL+ + A A+++EWLEA+G G   VT RLRDWLFSRQ
Sbjct  369  EAAFTEDGLHINSDF------LDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQ  422

Query  516  RYWGEPFPIVYDSTGAPIALPESMLPVELPEVEDFSPKTFDADDADSNPETPLSRRRDWV  575
            RYWGEP+PI+    G++ A+PES LP+ LP   D+ P         +  E+PL+   DW+
Sbjct  423  RYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTDWL  474

Query  576  EVELDLGDGPKRYTRETNVMPQWAGSCWYELRYLDPTDPQRFADPENEAYWMGPRRDGDC  635
            EV  + G   +   RETN MPQWAGS WY LRY+DP + +++AD E    W+        
Sbjct  475  EVTREDGVKGR---RETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWL--------  523

Query  636  GGTDLYVGGAEHAVLHLLYARFWHKVLYDLGHVSSFEPFRRLFNQGMIQAYAFVDPRGAY  695
               D+YVGGAEHAVLHLLYARFWHKVLYDLG V++ EPF++LFNQGMI + ++ D+RGA 
Sbjct  524  -PVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGAL  582

Query  696  VPAEEVVEVDGRWFHGET--EVRREYGKMGKSLKNVVTPDDMCAAYGADTFRVYEMSMGP  753
            V+++ V   DG  FH ET  E+ +  +KM+KSLKNVV PDD+   YGADT+RVYEM MGP
Sbjct  583  VATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGP  642

Query  754  LEVSRPWETRAVVGSYRFLQRVWRTVVDEQTGELRVTDEPADEATRRLLHKAIDGVRADM  813
            L+ S +W   ++ GS +FL+RV R +   +     +T+E ++ A  ++ + ++ +V  ++
Sbjct  643  LDASIAWSEEGLEGSRKFLDRVYRLITTKE-----ITEENSG-ALDKVYNETVKAVTEQV  696

Query  814  DGIRFNTAIAKLIELTNGLTRLARTPREVAEPLVLMVAPFAPHMAEELWRKL-GHDTSLA  872
            D ++FNTAIA+L+ + N+  +  +   + A  +V ++APFAPH++EELW+ L + + S++
Sbjct  697  DQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESIS  756

Query  873  YADFPVADPALLVAESVTYPVQVNGKVRGRVEVPADASEETVRAAAL--EAVAGTLGGKE  930
            Y   P  D + LV + V   VQ++GKV++++ V+ D S E ++  AL  E V + ++GK+
Sbjct  757  YVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKD  816

Query  931  PRKVIVVKGRMVSVV  945
              KVI V  ++V++V
Sbjct  817  IIKVIAVPNKLVNIV  831


 Score =  130 bits (478),  Expect = 3e-31, Method: Compositional matrix adjust.
 Identities = 73/149 (49%), Positives = 101/149 (68%), Gaps = 11/149 (7%)

Query  24   IEHRWQDTWEREGTFHAPNPVGPLADPGHPRAGAEKLYVLDMFPYPSGAGLHVGHPLGYI  83
            IE +WQ  W  + TF +       +D++ P     K+Y LDMFPYPSGAGLHVGHP GY 
Sbjct  9    IEPKWQAFWADNHTFKTG------TDASKP-----KFYALDMFPYPSGAGLHVGHPEGYT  57

Query  84   GTDCYARYQRMAGRNVLHAMGFDAFGLPAEQYAVQTGTHPRTTTEANIERYREQLRRLGL  143
            +TD  +R++R  G+NVLH+MG DAFGLPAEQYA++TG +P   T  NI  ++ Q+  LG+
Sbjct  58   ATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGF  117

Query  144  GHDERRSVATIDTDFYRWTQWIFLQIFNS  172
            + D  R V T D ++Y+WTQWIF ++++ 
Sbjct  118  SYDWDREVNTTDPNYYKWTQWIFTKLYEK  146

1514) leuS in NC_019951


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  511 bits (1926),  Expect = 1e-145, Method: Compositional matrix adjust.
 Identities = 349/740 (48%), Positives = 501/740 (68%), Gaps = 57/740 (7%)

Query  232  LVYRADSLVNWCPGLGTVLANEEVTADGRSDRGNFPVFRKRLRQWMMRITAYAdrllddl  291
            L Y A+  VNW   LGT +ANEEV +DG S+RG +PV RK +RQWM++ITAYA+RLL+DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  292  dvldWPEQVKTMQRNWIGRSTGAVALFSARAASDDGFEVDIEVFTTRPDTLFGATYLVLA  351
            + +DWPE +K MQRNWIG+STGA   F  + +     + D+ VFTTRPDTLFGATY VLA
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDT-----DKDFTVFTTRPDTLFGATYAVLA  262

Query  352  PEHDLVDELVAASWPAGVNPLWTYGGGTPGEaiaayrraiaaKSDLERQE-SREKTGVFL  410
            PEH LVD + ++                 +EA+A Y+R  + KSDL R + ++EKTGV  
Sbjct  263  PEHALVDAITTSD---------------QAEAVADYKRQASLKSDLARTDLAKEKTGVWT  307

Query  411  GSYAINPANGEPVPIFIADYVLAGYGTGAIMAVPGHDQRDWDFARAFGLPIVEVIAGGNI  470
            GSYAINP NG  +P+ IADYVLA+YGTGAIMAVP+HD+RDW+FA+ F L I+ V+ GGN+
Sbjct  308  GSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNV  367

Query  471  SESAYTGDGILVNSDYLDGMSVPAAKRAIVDRLESAGRGRARIEFKLRDWLFARQRYWGE  530
             E+A+T DG+ +NSD+LDG+  ++A   +V++LE+ G G   + ++LRDWLF+RQRYWGE
Sbjct  368  EEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGE  427

Query  531  PFPIVYDSDGRPHALDEAALPVELPDVPDYSPVLFdpddadsepsppLAKATEWVHVDLD  590
            P+PI+   DG + A+ E+ LP+ LP   D  P         +   +PLA+ T+W++V  +
Sbjct  428  PIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTDWLEVTRE  479

Query  591  LGDGLKPYSRDTNVMPQWAGSSWYELRYTDPHNSERFCAKENEAYWMGPRPAEHGPDDPG  650
              DG+K   R+TN MPQWAGSSWY LRY DPHN+E++   E    W+             
Sbjct  480  --DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWL-------------  523

Query  651  GVDLYVGGAEHAVLHLLYSRFWHKVLYDLGHVSSREPYRRLVNQGYIQAYAYTDARGSYV  710
             VD+YVGGAEHAVLHLLY+RFWHKVLYDLG V+++EP+++L NQG I + +Y D+RG+ V
Sbjct  524  PVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALV  583

Query  711  PAEQVIERGDRFVYPGPDGEIEVFQEFGKIGKSLKNSVSPDEICDAYGADTLRVYEMSMG  770
            ++++V  R++ F     + E+E  Q  +K++KSLKN V+PD++ + YGADTLRVYEM MG
Sbjct  584  ATDKVEKRDGSFFHVETGEELE--QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMG  641

Query  771  PLEASRPWATKDVVGAYRFLQRVWRLVVDEHTGETRVADGVELDIDTLRALHRTIVGVSE  830
            PL+AS +W+  ++ G+ +FL+RV RL+   +  E    ++  LD    +  + T+ +V+E
Sbjct  642  PLDASIAWSEEGLEGSRKFLDRVYRLITTKEITE---ENSGALD----KVYNETVKAVTE  694

Query  831  DFAALRNNTATAKLIEYTNHLTKKHRDAVPRAAVEPLVQMLAPLAPHIAEELWLRLGNTT  890
            +   ++ NTA A+L+ + N   K ++  +       +VQ++AP+APH++EELW  L  + 
Sbjct  695  QVDQMKFNTAIAQLMVFVNAANKEDK--LFSDYAKGFVQLIAPFAPHLGEELWQALTASG  752

Query  891  -SLAHGPFPKANAAYLVDETVEYPVQVNGKVRGRVVVAADTDEETLKAAVLTDEKVQAFL  949
             S++  P P  + + LV++ VE  VQ++GKV++++VVA D   E L+   L++EKVQA +
Sbjct  753  ESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEI  812

Query  950  AGATPRKVIVVAGRLVNLVI  969
            AG    KVI V+ +LVN+VI
Sbjct  813  AGKDIIKVIAVPNKLVNIVI  832


 Score =  129 bits (474),  Expect = 7e-31, Method: Compositional matrix adjust.
 Identities = 73/148 (50%), Positives = 99/148 (67%), Gaps = 11/148 (7%)

Query  35   LERTWQENWARLGTFNVPNPVGSLAPPDGAAVPDDKLFVQDMFPYPSGEGLHVGHPLGYI  94
            +E  WQ  WA   TF+            G+  +  K++  DMFPYPSG GLHVGHP GY 
Sbjct  9    IEPKWQAFWADNHTFKT-----------GTDASKPKFYALDMFPYPSGAGLHVGHPEGYT  57

Query  95   ATDVYARYFRMVGRNVLHALGFDAFGLPAEQYAVQTGTHPRTRTEANVVNFRRQLGRLGF  154
            ATD+ +R+ R  G+NVLH++G DAFGLPAEQYA++TG +P   T  N+ NF+RQ+  LGF
Sbjct  58   ATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGF  117

Query  155  GHDSRRSFSTTDVDFYRWTQWIFLQIYN  182
            + D  R  +TTD ++Y+WTQWIF ++Y+
Sbjct  118  SYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1515) leuS in NC_019952


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  511 bits (1926),  Expect = 1e-145, Method: Compositional matrix adjust.
 Identities = 350/740 (48%), Positives = 501/740 (68%), Gaps = 57/740 (7%)

Query  232  LVYRADSLVNWCPGLGTVLANEEVTADGRSDRGNFPVFRKRLRQWMMRITAYAdrllddl  291
            L Y A+  VNW   LGT +ANEEV +DG S+RG +PV RK +RQWM++ITAYA+RLL+DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  292  dvldWPEQVKTMQRNWIGRSTGAVALFSARAASDDGFEVDIEVFTTRPDTLFGATYLVLA  351
            + +DWPE +K MQRNWIG+STGA   F  + +     + D+ VFTTRPDTLFGATY VLA
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDT-----DKDFTVFTTRPDTLFGATYAVLA  262

Query  352  PEHDLVDELVAASWPAGVNPLWTYGGGTPGEavaayrraiaaKSDLERQE-SREKTGVFL  410
            PEH LVD + ++                 +EAVA Y+R  + KSDL R + ++EKTGV  
Sbjct  263  PEHALVDAITTSD---------------QAEAVADYKRQASLKSDLARTDLAKEKTGVWT  307

Query  411  GSYAINPANGEPVPIFIADYVLAGYGTGAIMAVPGHDQRDWDFARAFGLPIVEVIAGGNI  470
            GSYAINP NG  +P+ IADYVLA+YGTGAIMAVP+HD+RDW+FA+ F L I+ V+ GGN+
Sbjct  308  GSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNV  367

Query  471  SESAYTGDGILVNSDYLDGMSVPAAKRAIVDRLESAGRGRARIEFKLRDWLFARQRYWGE  530
             E+A+T DG+ +NSD+LDG+  ++A   +V++LE+ G G   + ++LRDWLF+RQRYWGE
Sbjct  368  EEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGE  427

Query  531  PFPIVYASDGRPHALDEAALPVELPDVPDYSPVLFdpddadsepsppLAKATEWVHVELD  590
            P+PI+   DG + A+ E+ LP+ LP   D  P         +   +PLA+ T+W++V  +
Sbjct  428  PIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTDWLEVTRE  479

Query  591  LGDGLKPYSRDTNVMPQWAGSSWYELRYTDPHNSERFCAKENEAYWMGPRPAEHGPDDPG  650
              DG+K   R+TN MPQWAGSSWY LRY DPHN+E++   E    W+             
Sbjct  480  --DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWL-------------  523

Query  651  GVDLYVGGAEHAVLHLLYSRFWHKVLYDLGHVSSREPYRRLVNQGYIQAYAYTDARGSYV  710
             VD+YVGGAEHAVLHLLY+RFWHKVLYDLG V+++EP+++L NQG I + +Y D+RG+ V
Sbjct  524  PVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALV  583

Query  711  PAEQVIERGDRFVYPGPDGEIEVFQEFGKIGKSLKNSVSPDEICDAYGADTLRVYEMSMG  770
            ++++V  R++ F     + E+E  Q  +K++KSLKN V+PD++ + YGADTLRVYEM MG
Sbjct  584  ATDKVEKRDGSFFHVETGEELE--QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMG  641

Query  771  PLEASRPWATKDVVGAYRFLQRVWRLVVDEHTGETRVADGVELDIDTLRALHRTIVGVSE  830
            PL+AS +W+  ++ G+ +FL+RV RL+   +  E    ++  LD    +  + T+ +V+E
Sbjct  642  PLDASIAWSEEGLEGSRKFLDRVYRLITTKEITE---ENSGALD----KVYNETVKAVTE  694

Query  831  DFAALRNNTATAKLIEYTNHLTKKHRDAVPRPAVEPLVQMLAPLAPHIAEELWLRLGNTT  890
            +   ++ NTA A+L+ + N   K ++  +       +VQ++AP+APH++EELW  L  + 
Sbjct  695  QVDQMKFNTAIAQLMVFVNAANKEDK--LFSDYAKGFVQLIAPFAPHLGEELWQALTASG  752

Query  891  -SLAHGPFPKADAAYLVDETVEYPVQVNGKVRGRVVVAADTDEETLKAAVLTDEKVQAFL  949
             S++  P P  D + LV++ VE  VQ++GKV++++VVA D   E L+   L++EKVQA +
Sbjct  753  ESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEI  812

Query  950  AGATPRKVIVIAGRLVNLVI  969
            AG    KVI ++ +LVN+VI
Sbjct  813  AGKDIIKVIAVPNKLVNIVI  832


 Score =  129 bits (474),  Expect = 7e-31, Method: Compositional matrix adjust.
 Identities = 73/148 (50%), Positives = 99/148 (67%), Gaps = 11/148 (7%)

Query  35   LERTWQENWARLGTFNVPNPVGSLAPPDGAAVPDDKLFVQDMFPYPSGEGLHVGHPLGYI  94
            +E  WQ  WA   TF+            G+  +  K++  DMFPYPSG GLHVGHP GY 
Sbjct  9    IEPKWQAFWADNHTFKT-----------GTDASKPKFYALDMFPYPSGAGLHVGHPEGYT  57

Query  95   ATDVYARYFRMVGRNVLHALGFDAFGLPAEQYAVQTGTHPRTRTEANVVNFRRQLGRLGF  154
            ATD+ +R+ R  G+NVLH++G DAFGLPAEQYA++TG +P   T  N+ NF+RQ+  LGF
Sbjct  58   ATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGF  117

Query  155  GHDSRRSFSTTDVDFYRWTQWIFLQIYN  182
            + D  R  +TTD ++Y+WTQWIF ++Y+
Sbjct  118  SYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1516) Desti_3834 in NC_018025


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  511 bits (1926),  Expect = 1e-145, Method: Compositional matrix adjust.
 Identities = 353/859 (42%), Positives = 532/859 (62%), Gaps = 69/859 (8%)

Query  5    YNPEAIEKKWQNFWDKEKLFKVELNSSKEKYYLLEMFPYPSGR-IHMGHVRNYSIGDVVA  63
            Y+  AIE KWQ FW  +  FK   ++SK K+Y L+MFPYPSG  +H+GH   Y+  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RFKMMQGLNVLHPMGWDAFGMPAENAAIKHGSHPAKWTMQNIDEMRRQLKRMGFSYDWDR  123
            RFK  QG NVLHPMGWDAFG+PAE+ A+  G++PA  T +NI + +RQ++ +GFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EIATCHPEYYRWEQWLFARMMDRGLVYRKKSIVNYCEPCQTVLANEQV-EDGACWRCGTP  182
            E+ T +P+YY+W QW+F+++ ++GL Y     VN  E   T +ANE+V  DG+  R G P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VVHKDQEGWFFKITDYAAELLEWCDKLPGWPEKVLIMQRNWIGRSEGAKILFGIENSDES  242
            VV+K    W +KIT YA  LLE  + + +WPE +  MQRNWIG+S GA++ F + ++D  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  IEVFTTRPDTLYGATFMSLAPEHPLALRLSKGTPQETKVRDFVQKVLQQEWENRVGDQAE  302
            + VFTTRPDTL+GAT+  LAPEH+L   ++ +   E+ V D+ ++   +    R +   E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEA-VADYKRQASLKSDLARTDLAKE  301

Query  303  KEGVFTGAYCINPVTGWRMPIYVANFVLYEYGTGAVMAVPAHDQRDFEFAKKYGLRIVVV  362
            K GV TG+Y INPV G  MP+ +A++VL  YGTGA+MAVPAHD+RD EFAK++ L I+ V
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  363  IQPEGQPLNAETMTEAYVDPGVLVNSNGFDGTENESAKKAICDKLASENKGGATINYRIR  422
            ++       ++    A+ + G+ +NS+ +DG ++ SA   + + L +E  G   + YR+R
Sbjct  362  LE------GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  423  DWGISRQRYWGAPIPIIH--CPKCGavpvpdadlpvvlpvdIEFPTNGRSPLPDLDWWVN  480
            DW +SRQRYWG PIPIIH       AVP ++  L + +  DI  +  G SPL+++  W++
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  481  VPCPKCGEPARRETDTMDTFVESSWYFDRYACPRYDKGIIDPETNEYWLPVDQYIGGIEH  540
            V     G  +RRET+TM     SSWY+ RY  P+    + D E    WLPVD Y+GG EH
Sbjct  476  VTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEH  534

Query  541  AILHLLYSRFFTKVLRDLGIKKWDEPFTNLLTQGMVI-------------------KDG-  580
            A+LHLLY+RF  KVL DLG+    EPF +L+ QGM++                   +DG 
Sbjct  535  AVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGS  594

Query  581  --------------AKMSKSKGNVVDPEELIDRYGADTVRLFCLFAAPPERDLEWTSEGV  626
                          AKMSKS  NVV+P++++++YGADT+R++ +F +P +  + W+ EG+
Sbjct  595  FFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGL  654

Query  627  EGSYRFIGRVWNLVAQLGNYRIPKTAAEDTDRSRQIRRLTHKTIKKVTDDIQNRFHFNTA  686
            EGS +F++RV         YR+  T     + S  + ++ + T+K VT+++ ++  FNTA
Sbjct  655  EGSRKFLDRV---------YRLITTKEITEENSGALDKVYNETVKAVTEQV-DQMKFNTA  704

Query  687  VAAVMEMANEIGKTMQEEAQPAPAIALALHEAVRSMIILLSPFIPHVCEELWEALGEKPG  746
            +A +M   N   K  +            + +  ++ + L++PF PH+ EELW+AL     
Sbjct  705  IAQLMVFVNAANKEDK-----------LFSDYAKGFVQLIAPFAPHLGEELWQALTASGE  753

Query  747  MVR-IPWPSYDPAlleqnqvvlvvqvnGKKRGEIVVSVDASEEEIRTTALEQENVGKFLE  805
             +  +PWPSYD + L +N+V +VVQ++GK ++ +VV+ D S EE++  AL +E+V   + 
Sbjct  754  SISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIA  813

Query  806  GKSIRKTVLVPGRILNLVV  824
            GK I K + VP +++N+V+
Sbjct  814  GKDIIKVIAVPNKLVNIVI  832

1517) Psed_6668 in NC_015312


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  511 bits (1929),  Expect = 7e-146, Method: Compositional matrix adjust.
 Identities = 354/737 (49%), Positives = 491/737 (67%), Gaps = 58/737 (7%)

Query  224  LAYISEAPVNWCPGLGTVLANEEVTADGRSERGNFPVFRRNLKQWMMRITAYSDRLVADL  283
            LAY +E PVNW   LGT +ANEEV +DG SERG +PV R+ ++QWM++ITAY++RL+ DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  284  DRLDWPESVKAMQRNWIGRSEGARVRFAVEGSDEPIEVFTTRPDTLFGATYMVLAPEHPL  343
            + +DWPES+K MQRNWIG+S GA V F V ++D  + VFTTRPDTLFGATY VLAPEH+L
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  344  VDAIVPARWPGDVDARWTGGAATPGEAVAGYREAAARKSELDRQE-NKEKTGVFTGAYAT  402
            VDAI                ++  +EAVA+Y+  A+ KS+L R +  KEKTGV TG+YA 
Sbjct  268  VDAI---------------TTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAI  312

Query  403  NPVNGERIPVFVADYVLMGYGTGAIMAVPAQDTRDWEFATTFGLPIVRTVDPGEGWDGEA  462
            NPVNG  +PV +ADYVL +YGTGAIMAVPA+D RDWEFA  F L I+  ++ G+  +  A
Sbjct  313  NPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNV-EEAA  371

Query  463  FTGDGPAINSANDEVSLNGLGVADAKRTIIDWLAGKGFGESVVQYKLRDWLFSRQRYWGE  522
            FT DG  INS      L+GL+ A A   +++WL + G G+  V Y+LRDWLFSRQRYWGE
Sbjct  372  FTEDGLHINSD----FLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGE  427

Query  523  PFPIV-WDEHGPVGLPDSELPVELPDVDDYSPKTYdpddadtepeppLSRATEWVETELD  581
            P+PI+ W++  + ++P+SELP+ LP   D  P            E+PL+  T+W+E   +
Sbjct  428  PIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSG--------TGESPLANVTDWLEVTRE  479

Query  582  LGDGPRAYRRETNTMPQWAGSCWYYLRYLDPDNHERFVSEEAEKYWVGKDLQRSAADPGG  641
              DG ++ RRETNTMPQWAGS WYYLRY+DP+N E++  EE  K W+             
Sbjct  480  --DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWL------------P  524

Query  642  VDLYVGGVEHAVLHLLYSRFWHKVLFDLGHVSSEEPFRTLFNQGYIQAYAYTDARGLYVP  701
            VD+YVGG EHAVLHLLY+RFWHKVL+DLG V++ EPF+ LFNQG I + +Y D+RG  V+
Sbjct  525  VDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVA  584

Query  702  AEEVVEGDDGGFTW--NGEPVTREYGKMGKSLKNVVTPDEMCDRYGADTFRLYEMYTGPM  759
            ++  VE  DG+F     GE + +  +KM+KSLKNVV PD++ ++YGADT+R+YEM+ GP+
Sbjct  585  TDK-VEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPL  643

Query  760  EASRPWSTRDVVGPQRFLQRVWRNIVDEETGECRVTDDALDEDTLRALHKAIAGVHEDFP  819
            +AS +WS  ++ G+++FL+RV R I   E  E     +ALD    +  + ++ +V E+  
Sbjct  644  DASIAWSEEGLEGSRKFLDRVYRLITTKEITE--ENSGALD----KVYNETVKAVTEQVD  697

Query  820  ALHYNTAAAKLIELNNHLTKVYGGAGVPRAVAEPLVLMLAPLAPHVAEELWAILGHDG-S  878
             + +NTA A+L+ + N   K      +    A  +V ++AP+APH++EELW  L   G S
Sbjct  698  QMKFNTAIAQLMVFVNAANK---EDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGES  754

Query  879  LAYEPFPVADARYLVAETAEYPIQFNGKVRSRITvpaaadvatvqaaaladekiaallDG  938
            ++Y P P  D   LV +  E  +Q++GKV++++ V+       +Q  ALA+EK+ A + G
Sbjct  755  ISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAG  814

Query  939  REPRKVIVVPGRLVNIV  955
            ++  KVI VP +LVNIV
Sbjct  815  KDIIKVIAVPNKLVNIV  831


 Score =  137 bits (503),  Expect = 4e-33, Method: Compositional matrix adjust.
 Identities = 75/142 (53%), Positives = 102/142 (72%), Gaps = 4/142 (2%)

Query  34   IERKWQDRWEAEGTFRAPNPGEPGSERKKVYLLDMFPYPSGAGLHVGHPLGFIGTDVLGR  93
            IE KWQ  W  + TF++      ++ + K Y LDMFPYPSGAGLHVGHP G+ +TD+L+R
Sbjct  9    IEPKWQAFWADNHTFKT----GTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSR  64

Query  94   YLRMTGHNVLHAMGFDAFGLPAEQYAVQTGTHPRTTTEANIARYREQLRQLGLAHDDRRS  153
            + R  GHNVLH+MG DAFGLPAEQYA++TG +P   T  NIA ++ Q+  LG++ D  R 
Sbjct  65   FKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDRE  124

Query  154  VATTDVEFYRWTQWIFLQIFNS  175
            V TTD ++Y+WTQWIF ++++ 
Sbjct  125  VNTTDPNYYKWTQWIFTKLYEK  146

1518) leuS in NC_014960


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  510 bits (1924),  Expect = 1e-145, Method: Compositional matrix adjust.
 Identities = 354/851 (42%), Positives = 516/851 (61%), Gaps = 59/851 (6%)

Query  6    VRIYNPAEIESRWQERWEKDGLYHSDIDPNKPKHYALTMLPYPSG-NLHIGHWYAMTPSD  64
            + +Y+ + IE++WQ  W  +  + ++ D++KPK YAL M+PYPSG  LH+GH  + T++D
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  65   ARARFMRMRGYNVLFPMGFDAFGLPAENAAIKRNIHPKEWTYQNIDNMRRQLKSMGAMFD  124
              +RF R +G NVL PMG DAFGLPAE+ A+    +P E T +NI N +RQ++++G  +D
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  125  WRREAISSDPEYYRWTQWFFIQFYKHGLAYRKMSPVDWCPTCNTTLAREQVWGEDRHCER  184
            W RE  ++DP+YY+WTQW+F ++Y  GLAY    PV+W     T++A E+V  ++   ER
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGT-SER  179

Query  185  CGTPVIKKNLEQWFFKTTQYAEELLR-YEGMDWPEKVREMQINWIGKSEGASVIFSTEQG  243
             G PV++K + QW +K T YAE LL   E +DWPE +++MQ NWIGKS GA+V F   + 
Sbjct  180  GGYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDT  239

Query  244  D-PLEVFTTRPDTLWGVTFMVLAPEHPLVEKVTTPERKAEVDAYVAQAIRQSDIQRESTE  302
            D  + VFTTRPDTL G T+ VLAPEH+LV+ +TT+++   V  Y  QA  +SD+ R    
Sbjct  240  DKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA  299

Query  303  KEKTGVFTGGYAINPVNGERVPIWIADYVLMTYGTGAIMAVPAHDQRDFEFARKYGLPVR  362
            KEKTGV TG+YAINPVNG  +P+WIADYVL +YGTGAIMAVPAHD+RD EFA+++ L + 
Sbjct  300  KEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDII  359

Query  363  VVIQPEDMEPLNGDALTEAVPAKGKMVNSGPLTGTPGDQSFEAAVKYVEQIGKGKRAVNY  422
             V++  ++E         A    G  +NS+ L G     ++   V  +E  G G+  V Y
Sbjct  360  PVLEGGNVE-------EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTY  412

Query  423  RLRDWLISRQRYWGAPIPMVYCEKCGVVPVPEDQLPVLLPDDVEWRP--TGESPLKLHPT  480
            RLRDWL+SRQRYWG PIP++  E     +VPE +LP++LP   + RP  TGESPL     
Sbjct  413  RLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTD  472

Query  481  WRFTTCPSCGGKAERETDTMDTFMCSSWYHLRYLSPHYDKGPFDPKEYDYWMPVDTYTGG  540
            W +      G K+ RET+TM     SSWY LRY+ PH      D      W+PVD Y GG
Sbjct  473  W-LEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGG  531

Query  541  AEHATMHLIYTRFFHKACRDIGITKGNEPMIQLRNQGQILGPD-----------------  583
            AEHA +HL+Y+RF HK   D+G+   +EP  +L NQG ILG                   
Sbjct  532  AEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKR  591

Query  584  ----------------GQRMSKSRGNVVDPDEQVRMYGADTVRAFLMFGYRWAEGGPWGT  627
                              +MSKS  NVV+PD+ V  YGADT+R + MF      + +W+ 
Sbjct  592  DGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSE  651

Query  628  ENIQGVNRWLRRVWSFFLDEADGGKADEATFKRLRRKVHQTLRSVTRDFEEFEFNTIVSA  687
            E ++G  + L RV  + L  +     +++    L +  ++T+++VT + ++  FNT ++ 
Sbjct  652  EGLEGSRKFLDRV--YRLITTKEITEENSG--ALDKVYNETVKAVTEQVDQMKFNTAIAQ  707

Query  688  LMELANEMSRAKQNGAFGTPVWDEAVEIYLKMLAPVAPHIAEELWAQL-GKPYSIHQQSW  746
            LM + N  +  K++  F+     +    +++++AP APH++EELW  L +   SI   +W
Sbjct  708  LMVFVN--AANKEDKLFS-----DYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPW  760

Query  747  PLVDEEAAKEEEITLAVQVNGKVRDRLVVPAEIDRETVEKLALASPAVQKFLEGRTPRQV  806
            P  DE    E+++ + VQ++GKV+ +LVV+ ++ RE ++ +ALA+  VQ  + G+   +V
Sbjct  761  PSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKV  820

Query  807  IYVPGKLVSIV  817
            I VP KLV+IV
Sbjct  821  IAVPNKLVNIV  831

1519) A225_1672 in NC_018106


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  510 bits (1925),  Expect = 1e-145, Method: Compositional matrix adjust.
 Identities = 358/865 (42%), Positives = 542/865 (63%), Gaps = 46/865 (5%)

Query  5    YRPEEIESKVQQHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIS  63
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKKLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            EV T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYAdellndldnldHWPDTVKTMQRNWIGRSEGVEISFDVNDYADK  242
            V RK + QW +KITAYA E L +  +  +WP+++K MQRNWIG+S G +++F V+D    
Sbjct  184  VVRKPMRQWMLKITAYA-ERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGCTY--LavaaghplaqqaaannpalaTFI-DECRNTKVAEAEMATME  299
            +TV+TTRPDT+ G TY  LA   +   A  ++ +  A+A +  +   ++ +A +++A  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGVDTGYKAIHPLTGEAIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPV  359
            K GV TG  AI+P+ G  +PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L+I PV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  360  ILAADGSEPDLSEQALTEKGVLFNSGEFDGLDHEAGFNAIADKLASLGVGERKVNYRLRD  419
            +        ++ E A+TE G+ +NS+ +DGLD  +++  + + L + GVG+ +V YRLRD
Sbjct  362  L-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMVTLEDGTVMPTPEDQLPVILP--EDVVMDGIT-SPIKADPEWAKT  476
            W  SRQRYWG PIP++  EDGT  + PE +LP++LP   D+   G   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  T-VNGQPALRETDTFDTFMESSWYYARYTCPQYDQGMLDPEAANYWLPVDIYIGGIEHAI  535
            T  +G  + RET+T      SSWYY RY  P+  + + D E  + WLPVDIY+GG EHA+
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPKEATTER  595
            +HLLY RF HK++ D G+V + EP ++L+ QGM+L+ +  Y +  G          +T++
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS--YRDSRGAL-------VATDK  587

Query  596  DEKGRIVKAFDPQGRELVYTGMSKMSKSKNNGIDPQEMVERYGADTVRLFMMFASPADMT  655
             EK R    F+ +  E +  + +KMSKS +N ++P+++VE+YGADT+R++ MF +P D +
Sbjct  588  VEK-RDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  656  LEWQESGVEGANRFLKRVWKLVYEHTTLGEAPALDVASLSEDQKALRRDVHKTIAKVTDD  715
            + W E G+EG+ +FL RV +L+       E ++           AL +  + T+  VT++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLITTKEITEENSG-----------ALDKVYNETVKAVTEQ  695

Query  716  IGRRQTFNTAIAAIMELMNKLAKAPQENDQDRALMREALLAVVRMLNPFTPHASFTLWQE  775
            +++ + FNTAIA +M ++N         +++  L  +   + V+++ PF+PH +  LWQ 
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  776  LGGEGD-IDNTPWPVADESAMVEDTTLVVVQVNGKVRGKITVAVDATEEQVRERAGQEHL  834
            L + G+ I   PWP  DES +VE+   +VVQ++GKV++K+ VA D + E+++E A  ++ 
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  835  VAKYLDGVTVRKVIYVPGKLLNLVV  859
            V   + G  + KVI VP KL+N+V+
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVI  832

1520) leuS in NC_016612


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  510 bits (1925),  Expect = 1e-145, Method: Compositional matrix adjust.
 Identities = 358/865 (42%), Positives = 542/865 (63%), Gaps = 46/865 (5%)

Query  5    YRPEEIESKVQQHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIS  63
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKKLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            EV T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYAdellndldnldHWPDTVKTMQRNWIGRSEGVEISFDVNDYADK  242
            V RK + QW +KITAYA E L +  +  +WP+++K MQRNWIG+S G +++F V+D    
Sbjct  184  VVRKPMRQWMLKITAYA-ERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGCTY--LavaaghplaqqaaannpalaTFI-DECRNTKVAEAEMATME  299
            +TV+TTRPDT+ G TY  LA   +   A  ++ +  A+A +  +   ++ +A +++A  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGVDTGYKAIHPLTGEAIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPV  359
            K GV TG  AI+P+ G  +PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L+I PV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  360  ILAADGSEPDLSEQALTEKGVLFNSGEFDGLDHEAGFNAIADKLASLGVGERKVNYRLRD  419
            +        ++ E A+TE G+ +NS+ +DGLD  +++  + + L + GVG+ +V YRLRD
Sbjct  362  L-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMVTLEDGTVMPTPEDQLPVILP--EDVVMDGIT-SPIKADPEWAKT  476
            W  SRQRYWG PIP++  EDGT  + PE +LP++LP   D+   G   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  T-VNGQPALRETDTFDTFMESSWYYARYTCPQYDQGMLDPEAANYWLPVDIYIGGIEHAI  535
            T  +G  + RET+T      SSWYY RY  P+  + + D E  + WLPVDIY+GG EHA+
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPKEATTER  595
            +HLLY RF HK++ D G+V + EP ++L+ QGM+L+ +  Y +  G          +T++
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS--YRDSRGAL-------VATDK  587

Query  596  DEKGRIVKAFDPQGRELVYTGMSKMSKSKNNGIDPQEMVERYGADTVRLFMMFASPADMT  655
             EK R    F+ +  E +  + +KMSKS +N ++P+++VE+YGADT+R++ MF +P D +
Sbjct  588  VEK-RDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  656  LEWQESGVEGANRFLKRVWKLVYEHTTLGEAPALDVASLSEDQKALRRDVHKTIAKVTDD  715
            + W E G+EG+ +FL RV +L+       E ++           AL +  + T+  VT++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLITTKEITEENSG-----------ALDKVYNETVKAVTEQ  695

Query  716  IGRRQTFNTAIAAIMELMNKLAKAPQENDQDRALMREALLAVVRMLNPFTPHASFTLWQE  775
            +++ + FNTAIA +M ++N         +++  L  +   + V+++ PF+PH +  LWQ 
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  776  LGGEGD-IDNTPWPVADESAMVEDTTLVVVQVNGKVRGKITVAVDATEEQVRERAGQEHL  834
            L + G+ I   PWP  DES +VE+   +VVQ++GKV++K+ VA D + E+++E A  ++ 
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  835  VAKYLDGVTVRKVIYVPGKLLNLVV  859
            V   + G  + KVI VP KL+N+V+
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVI  832

1521) leuS in NC_005042


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  510 bits (1925),  Expect = 1e-145, Method: Compositional matrix adjust.
 Identities = 344/841 (41%), Positives = 540/841 (65%), Gaps = 45/841 (5%)

Query  17   YDPLSIETRWQQSWKEQGLYKTKEPTKSQKTFYALSMFPYPSGT-LHMGHVRNYVITDVI  75
            YD  +IE +WQ  W ++  +KT   +   K FYAL MFPYPSG+ LH+GH   Y  TD++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPK-FYALDMFPYPSGAGLHVGHPEGYTATDIL  62

Query  76   ARLHRMKGDSVLHPMGWDAFGLPAENAAIERGIPADIWTYKNIEDMRNQLNRLGLSIDWD  135
            +R+ R +G++VLHPMGWDAFGLPAE+ A++ G  +   T  NI + + Q+N LG+S DWD
Sbjct  63   SRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWD  122

Query  136  KEVTTCKEEYYKWTQYIFLELYEAGLAYQKSATVNWDPIDKTVLANEQVDANGRSWRSGA  195
            +EV T   +YYKWTQ IF  LYE GLAY+    VNW     T +ANE+V ++G S R+G 
Sbjct  123  REVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGY  182

Query  196  LVEKKKLKQWFLKITDFADELLEDIELLSGWPQNVKTMQQNWIGRSNGTEIDFYIKGKNN  255
             V +K ++QW LKIT +A+ LLED+E + +WP+++K MQ+NWIG+S G+++ F +K+ ++
Sbjct  183  PVVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDK  241

Query  256  IFITVFTTRPDTLHGTEYLVLAPDHELINSIIDKNKITELEQFRTEISILTDQERTSDGN  315
             F TVFTTRPDTL G+ Y VLAP+H L+++I   ++   + +++ + S+ +D  RT  ++
Sbjct  242  DF-TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  316  NKRGMFLGCHAinpinkkiipiWVGEYVLSSYATGAVMGVPAHDKRDYKFAKKYSLPIQY  375
            +K G+  G  AINP+N K +P+W+++YVL+SY+TGA+M+VPAHD RD  FAK+++L I  
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDI--  358

Query  376  VIKSPSQEASDLEASSAYVKEGIMINSGEFNGINSKEAGFMITKLGVKQGWAKNKVTYKL  435
                P  E++++E  +A+  +G+ INS+ ++G++   A   +      +G ++++VTY+L
Sbjct  359  ---IPVLEGGNVEE-AAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRL  414

Query  436  RDWLISRQRMWGCPIPIIYCPDCGSVPVKREELPVKLTNPSVIGKSQENKNNIPIMKCSK  495
            RDWL+SRQR WG PIPII   D  S +V   ELP+ L  P   +       + P+ + + 
Sbjct  415  RDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVL--PVTKDIRPSGTGESPLANVTD  472

Query  496  ---CNKDSIL----ETDTMDTFMCSSWYFLRYIDVENNKLPFTKTEVDKWLPVDQYVGGI  548
                 ++  +    ET+TM     SSWY+LRYID +N         + +WLPVD YVGG 
Sbjct  473  WLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGA  532

Query  549  EHAILHLLYSRFLIKALRNRGLLNIKEPFSNLLTQGMVQGVTFKNPKTSKYISPDHINDI  608
            EHA+LHLLY+RF  K L + G++  KEPF +L+ QGM+ G ++++++ +  ++ D ++  
Sbjct  533  EHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGA-LVATDKVEKR  591

Query  609  NTP-LDPETGEPLDVLYEKMSKSKYNGVDPASVIDKYGTDTARMFILFKAPPEKDLEWDE  667
            + + ++ ETGE L+    KMSKS  N V+P  V+++YG+DT R++ +F +P +  + W E
Sbjct  592  DGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSE  651

Query  668  SDVEGQYRFLNRLWRIVIYSIETKDINISNCTQEILLNDLSDKERKLIKVLNNTIKEVTN  727
             ++EG  +FL+R+ R+    I TK+I   N                L KV N+T+K VT+
Sbjct  652  EGLEGSRKFLDRVYRL----ITTKEITEENSGA-------------LDKVYNETVKAVTE  694

Query  728  DLVNDFQFNTAISELMILCNSIYENIDDCGDYIVTETFKKLTLLLAPFAPHIAEEFWIKL  787
            + V++ +FNTAI++LM++ N+   +    +DY      K +  L+APFAPH++EE+W  L
Sbjct  695  Q-VDQMKFNTAIAQLMVFVNAANKEDKLFSDYA-----KGFVQLIAPFAPHLGEELWQAL  748

Query  788  KGKG-SVHENSWPTYDPKALLEDSYKLIIQINGKVRGNISVNHEDSELELKNKALACETT  846
             + G S+   +WP+YD   L+E+   +++QI+GKV++++ V  + S  EL++ ALA E  
Sbjct  749  TASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKV  808

Query  847  Q  847
            Q
Sbjct  809  Q  809

1522) leuS in NC_015758


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  510 bits (1924),  Expect = 2e-145, Method: Compositional matrix adjust.
 Identities = 349/740 (48%), Positives = 501/740 (68%), Gaps = 57/740 (7%)

Query  232  LVYRADSLVNWCPGLGTVLANEEVTADGRSDRGNFPVFRKRLRQWMMRITAYAdrllddl  291
            L Y A+  VNW   LGT +ANEEV +DG S+RG +PV RK +RQWM++ITAYA+RLL+DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  292  dvldWPEQVKTMQRNWIGRSTGAVALFSARAASDDGFEVDIEVFTTRPDTLFGATYLVLA  351
            + +DWPE +K MQRNWIG+STGA   F  + +     + D+ VFTTRPDTLFGATY VLA
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDT-----DKDFTVFTTRPDTLFGATYAVLA  262

Query  352  PEHDLVDELVAASWPAGVNPLWTYGGGTPGEaiaayrraiaaKSDLERQE-SREKTGVFL  410
            PEH LVD + ++                 +EA+A Y+R  + KSDL R + ++EKTGV  
Sbjct  263  PEHALVDAITTSD---------------QAEAVADYKRQASLKSDLARTDLAKEKTGVWT  307

Query  411  GSYAINPANGEPVPIFIADYVLAGYGTGAIMAVPGHDQRDWDFARAFGLPIVEVIAGGNI  470
            GSYAINP NG  +P+ IADYVLA+YGTGAIMAVP+HD+RDW+FA+ F L I+ V+ GGN+
Sbjct  308  GSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNV  367

Query  471  SESAYTGDGILVNSDYLNGMSVPAAKRAIVDRLESAGRGRARIEFKLRDWLFARQRYWGE  530
             E+A+T DG+ +NSD+L+G+  ++A   +V++LE+ G G   + ++LRDWLF+RQRYWGE
Sbjct  368  EEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGE  427

Query  531  PFPIVYDSDGRPHALDEAALPVELPDVPDYSPVLFdpddadsepsppLAKATEWVHVDLD  590
            P+PI+   DG + A+ E+ LP+ LP   D  P         +   +PLA+ T+W++V  +
Sbjct  428  PIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTDWLEVTRE  479

Query  591  LGDGLKPYSRDTNVMPQWAGSSWYELRYTDPHNSERFCAKENEAYWMGPRPAEHGPDDPG  650
              DG+K   R+TN MPQWAGSSWY LRY DPHN+E++   E    W+             
Sbjct  480  --DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWL-------------  523

Query  651  GVDLYVGGAEHAVLHLLYSRFWHKVLYDLGHVSSREPYRRLVNQGYIQAYAYTDARGSYV  710
             VD+YVGGAEHAVLHLLY+RFWHKVLYDLG V+++EP+++L NQG I + +Y D+RG+ V
Sbjct  524  PVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALV  583

Query  711  PAEQVIERGDRFVYPGPDGEVEVFQEFGKIGKSLKNSVSPDEICDAYGADTLRVYEMSMG  770
            ++++V  R++ F     + E+E  Q  +K++KSLKN V+PD++ + YGADTLRVYEM MG
Sbjct  584  ATDKVEKRDGSFFHVETGEELE--QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMG  641

Query  771  PLEASRPWATKDVVGAYRFLQRVWRLVVDEHTGETRVADGVELDIDTLRALHRTIVGVSE  830
            PL+AS +W+  ++ G+ +FL+RV RL+   +  E    ++  LD    +  + T+ +V+E
Sbjct  642  PLDASIAWSEEGLEGSRKFLDRVYRLITTKEITE---ENSGALD----KVYNETVKAVTE  694

Query  831  DFAALRNNTATAKLIEYTNHLTKKHRDAVPRAAVEPLVQMLAPLAPHIAEELWLRLGNTT  890
            +   ++ NTA A+L+ + N   K ++  +       +VQ++AP+APH++EELW  L  + 
Sbjct  695  QVDQMKFNTAIAQLMVFVNAANKEDK--LFSDYAKGFVQLIAPFAPHLGEELWQALTASG  752

Query  891  -SLAHGPFPKADAAYLVDETVEYPVQVNGKVRGRVVVAADTDEETLKAAVLTDEKVQAFL  949
             S++  P P  D + LV++ VE  VQ++GKV++++VVA D   E L+   L++EKVQA +
Sbjct  753  ESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEI  812

Query  950  AGATPRKVIVVAGRLVNLVI  969
            AG    KVI V+ +LVN+VI
Sbjct  813  AGKDIIKVIAVPNKLVNIVI  832


 Score =  129 bits (474),  Expect = 7e-31, Method: Compositional matrix adjust.
 Identities = 73/148 (50%), Positives = 99/148 (67%), Gaps = 11/148 (7%)

Query  35   LERTWQENWARLGTFNVPNPVGSLAPPDGAAVPDDKLFVQDMFPYPSGEGLHVGHPLGYI  94
            +E  WQ  WA   TF+            G+  +  K++  DMFPYPSG GLHVGHP GY 
Sbjct  9    IEPKWQAFWADNHTFKT-----------GTDASKPKFYALDMFPYPSGAGLHVGHPEGYT  57

Query  95   ATDVYARYFRMVGRNVLHALGFDAFGLPAEQYAVQTGTHPRTRTEANVVNFRRQLGRLGF  154
            ATD+ +R+ R  G+NVLH++G DAFGLPAEQYA++TG +P   T  N+ NF+RQ+  LGF
Sbjct  58   ATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGF  117

Query  155  GHDSRRSFSTTDVDFYRWTQWIFLQIYN  182
            + D  R  +TTD ++Y+WTQWIF ++Y+
Sbjct  118  SYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1523) leuS in NC_002945


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  510 bits (1924),  Expect = 2e-145, Method: Compositional matrix adjust.
 Identities = 349/740 (48%), Positives = 501/740 (68%), Gaps = 57/740 (7%)

Query  232  LVYRADSLVNWCPGLGTVLANEEVTADGRSDRGNFPVFRKRLRQWMMRITAYAdrllddl  291
            L Y A+  VNW   LGT +ANEEV +DG S+RG +PV RK +RQWM++ITAYA+RLL+DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  292  dvldWPEQVKTMQRNWIGRSTGAVALFSARAASDDGFEVDIEVFTTRPDTLFGATYLVLA  351
            + +DWPE +K MQRNWIG+STGA   F  + +     + D+ VFTTRPDTLFGATY VLA
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDT-----DKDFTVFTTRPDTLFGATYAVLA  262

Query  352  PEHDLVDELVAASWPAGVNPLWTYGGGTPGEaiaayrraiaaKSDLERQE-SREKTGVFL  410
            PEH LVD + ++                 +EA+A Y+R  + KSDL R + ++EKTGV  
Sbjct  263  PEHALVDAITTSD---------------QAEAVADYKRQASLKSDLARTDLAKEKTGVWT  307

Query  411  GSYAINPANGEPVPIFIADYVLAGYGTGAIMAVPGHDQRDWDFARAFGLPIVEVIAGGNI  470
            GSYAINP NG  +P+ IADYVLA+YGTGAIMAVP+HD+RDW+FA+ F L I+ V+ GGN+
Sbjct  308  GSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNV  367

Query  471  SESAYTGDGILVNSDYLNGMSVPAAKRAIVDRLESAGRGRARIEFKLRDWLFARQRYWGE  530
             E+A+T DG+ +NSD+L+G+  ++A   +V++LE+ G G   + ++LRDWLF+RQRYWGE
Sbjct  368  EEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGE  427

Query  531  PFPIVYDSDGRPHALDEAALPVELPDVPDYSPVLFdpddadsepsppLAKATEWVHVDLD  590
            P+PI+   DG + A+ E+ LP+ LP   D  P         +   +PLA+ T+W++V  +
Sbjct  428  PIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTDWLEVTRE  479

Query  591  LGDGLKPYSRDTNVMPQWAGSSWYELRYTDPHNSERFCAKENEAYWMGPRPAEHGPDDPG  650
              DG+K   R+TN MPQWAGSSWY LRY DPHN+E++   E    W+             
Sbjct  480  --DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWL-------------  523

Query  651  GVDLYVGGAEHAVLHLLYSRFWHKVLYDLGHVSSREPYRRLVNQGYIQAYAYTDARGSYV  710
             VD+YVGGAEHAVLHLLY+RFWHKVLYDLG V+++EP+++L NQG I + +Y D+RG+ V
Sbjct  524  PVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALV  583

Query  711  PAEQVIERGDRFVYPGPDGEVEVFQEFGKIGKSLKNSVSPDEICDAYGADTLRVYEMSMG  770
            ++++V  R++ F     + E+E  Q  +K++KSLKN V+PD++ + YGADTLRVYEM MG
Sbjct  584  ATDKVEKRDGSFFHVETGEELE--QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMG  641

Query  771  PLEASRPWATKDVVGAYRFLQRVWRLVVDEHTGETRVADGVELDIDTLRALHRTIVGVSE  830
            PL+AS +W+  ++ G+ +FL+RV RL+   +  E    ++  LD    +  + T+ +V+E
Sbjct  642  PLDASIAWSEEGLEGSRKFLDRVYRLITTKEITE---ENSGALD----KVYNETVKAVTE  694

Query  831  DFAALRNNTATAKLIEYTNHLTKKHRDAVPRAAVEPLVQMLAPLAPHIAEELWLRLGNTT  890
            +   ++ NTA A+L+ + N   K ++  +       +VQ++AP+APH++EELW  L  + 
Sbjct  695  QVDQMKFNTAIAQLMVFVNAANKEDK--LFSDYAKGFVQLIAPFAPHLGEELWQALTASG  752

Query  891  -SLAHGPFPKADAAYLVDETVEYPVQVNGKVRGRVVVAADTDEETLKAAVLTDEKVQAFL  949
             S++  P P  D + LV++ VE  VQ++GKV++++VVA D   E L+   L++EKVQA +
Sbjct  753  ESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEI  812

Query  950  AGATPRKVIVVAGRLVNLVI  969
            AG    KVI V+ +LVN+VI
Sbjct  813  AGKDIIKVIAVPNKLVNIVI  832


 Score =  129 bits (474),  Expect = 7e-31, Method: Compositional matrix adjust.
 Identities = 73/148 (50%), Positives = 99/148 (67%), Gaps = 11/148 (7%)

Query  35   LERTWQENWARLGTFNVPNPVGSLAPPDGAAVPDDKLFVQDMFPYPSGEGLHVGHPLGYI  94
            +E  WQ  WA   TF+            G+  +  K++  DMFPYPSG GLHVGHP GY 
Sbjct  9    IEPKWQAFWADNHTFKT-----------GTDASKPKFYALDMFPYPSGAGLHVGHPEGYT  57

Query  95   ATDVYARYFRMVGRNVLHALGFDAFGLPAEQYAVQTGTHPRTRTEANVVNFRRQLGRLGF  154
            ATD+ +R+ R  G+NVLH++G DAFGLPAEQYA++TG +P   T  N+ NF+RQ+  LGF
Sbjct  58   ATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGF  117

Query  155  GHDSRRSFSTTDVDFYRWTQWIFLQIYN  182
            + D  R  +TTD ++Y+WTQWIF ++Y+
Sbjct  118  SYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1524) K60_000450 in NC_020245


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  510 bits (1924),  Expect = 2e-145, Method: Compositional matrix adjust.
 Identities = 349/740 (48%), Positives = 501/740 (68%), Gaps = 57/740 (7%)

Query  232  LVYRADSLVNWCPGLGTVLANEEVTADGRSDRGNFPVFRKRLRQWMMRITAYAdrllddl  291
            L Y A+  VNW   LGT +ANEEV +DG S+RG +PV RK +RQWM++ITAYA+RLL+DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  292  dvldWPEQVKTMQRNWIGRSTGAVALFSARAASDDGFEVDIEVFTTRPDTLFGATYLVLA  351
            + +DWPE +K MQRNWIG+STGA   F  + +     + D+ VFTTRPDTLFGATY VLA
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDT-----DKDFTVFTTRPDTLFGATYAVLA  262

Query  352  PEHDLVDELVAASWPAGVNPLWTYGGGTPGEaiaayrraiaaKSDLERQE-SREKTGVFL  410
            PEH LVD + ++                 +EA+A Y+R  + KSDL R + ++EKTGV  
Sbjct  263  PEHALVDAITTSD---------------QAEAVADYKRQASLKSDLARTDLAKEKTGVWT  307

Query  411  GSYAINPANGEPVPIFIADYVLAGYGTGAIMAVPGHDQRDWDFARAFGLPIVEVIAGGNI  470
            GSYAINP NG  +P+ IADYVLA+YGTGAIMAVP+HD+RDW+FA+ F L I+ V+ GGN+
Sbjct  308  GSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNV  367

Query  471  SESAYTGDGILVNSDYLNGMSVPAAKRAIVDRLESAGRGRARIEFKLRDWLFARQRYWGE  530
             E+A+T DG+ +NSD+L+G+  ++A   +V++LE+ G G   + ++LRDWLF+RQRYWGE
Sbjct  368  EEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGE  427

Query  531  PFPIVYDSDGRPHALDEAALPVELPDVPDYSPVLFdpddadsepsppLAKATEWVHVDLD  590
            P+PI+   DG + A+ E+ LP+ LP   D  P         +   +PLA+ T+W++V  +
Sbjct  428  PIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTDWLEVTRE  479

Query  591  LGDGLKPYSRDTNVMPQWAGSSWYELRYTDPHNSERFCAKENEAYWMGPRPAEHGPDDPG  650
              DG+K   R+TN MPQWAGSSWY LRY DPHN+E++   E    W+             
Sbjct  480  --DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWL-------------  523

Query  651  GVDLYVGGAEHAVLHLLYSRFWHKVLYDLGHVSSREPYRRLVNQGYIQAYAYTDARGSYV  710
             VD+YVGGAEHAVLHLLY+RFWHKVLYDLG V+++EP+++L NQG I + +Y D+RG+ V
Sbjct  524  PVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALV  583

Query  711  PAEQVIERGDRFVYPGPDGEVEVFQEFGKIGKSLKNSVSPDEICDAYGADTLRVYEMSMG  770
            ++++V  R++ F     + E+E  Q  +K++KSLKN V+PD++ + YGADTLRVYEM MG
Sbjct  584  ATDKVEKRDGSFFHVETGEELE--QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMG  641

Query  771  PLEASRPWATKDVVGAYRFLQRVWRLVVDEHTGETRVADGVELDIDTLRALHRTIVGVSE  830
            PL+AS +W+  ++ G+ +FL+RV RL+   +  E    ++  LD    +  + T+ +V+E
Sbjct  642  PLDASIAWSEEGLEGSRKFLDRVYRLITTKEITE---ENSGALD----KVYNETVKAVTE  694

Query  831  DFAALRNNTATAKLIEYTNHLTKKHRDAVPRAAVEPLVQMLAPLAPHIAEELWLRLGNTT  890
            +   ++ NTA A+L+ + N   K ++  +       +VQ++AP+APH++EELW  L  + 
Sbjct  695  QVDQMKFNTAIAQLMVFVNAANKEDK--LFSDYAKGFVQLIAPFAPHLGEELWQALTASG  752

Query  891  -SLAHGPFPKADAAYLVDETVEYPVQVNGKVRGRVVVAADTDEETLKAAVLTDEKVQAFL  949
             S++  P P  D + LV++ VE  VQ++GKV++++VVA D   E L+   L++EKVQA +
Sbjct  753  ESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEI  812

Query  950  AGATPRKVIVVAGRLVNLVI  969
            AG    KVI V+ +LVN+VI
Sbjct  813  AGKDIIKVIAVPNKLVNIVI  832


 Score =  129 bits (474),  Expect = 7e-31, Method: Compositional matrix adjust.
 Identities = 73/148 (50%), Positives = 99/148 (67%), Gaps = 11/148 (7%)

Query  35   LERTWQENWARLGTFNVPNPVGSLAPPDGAAVPDDKLFVQDMFPYPSGEGLHVGHPLGYI  94
            +E  WQ  WA   TF+            G+  +  K++  DMFPYPSG GLHVGHP GY 
Sbjct  9    IEPKWQAFWADNHTFKT-----------GTDASKPKFYALDMFPYPSGAGLHVGHPEGYT  57

Query  95   ATDVYARYFRMVGRNVLHALGFDAFGLPAEQYAVQTGTHPRTRTEANVVNFRRQLGRLGF  154
            ATD+ +R+ R  G+NVLH++G DAFGLPAEQYA++TG +P   T  N+ NF+RQ+  LGF
Sbjct  58   ATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGF  117

Query  155  GHDSRRSFSTTDVDFYRWTQWIFLQIYN  182
            + D  R  +TTD ++Y+WTQWIF ++Y+
Sbjct  118  SYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1525) leuS in NC_016804


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  510 bits (1924),  Expect = 2e-145, Method: Compositional matrix adjust.
 Identities = 349/740 (48%), Positives = 501/740 (68%), Gaps = 57/740 (7%)

Query  232  LVYRADSLVNWCPGLGTVLANEEVTADGRSDRGNFPVFRKRLRQWMMRITAYAdrllddl  291
            L Y A+  VNW   LGT +ANEEV +DG S+RG +PV RK +RQWM++ITAYA+RLL+DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  292  dvldWPEQVKTMQRNWIGRSTGAVALFSARAASDDGFEVDIEVFTTRPDTLFGATYLVLA  351
            + +DWPE +K MQRNWIG+STGA   F  + +     + D+ VFTTRPDTLFGATY VLA
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDT-----DKDFTVFTTRPDTLFGATYAVLA  262

Query  352  PEHDLVDELVAASWPAGVNPLWTYGGGTPGEaiaayrraiaaKSDLERQE-SREKTGVFL  410
            PEH LVD + ++                 +EA+A Y+R  + KSDL R + ++EKTGV  
Sbjct  263  PEHALVDAITTSD---------------QAEAVADYKRQASLKSDLARTDLAKEKTGVWT  307

Query  411  GSYAINPANGEPVPIFIADYVLAGYGTGAIMAVPGHDQRDWDFARAFGLPIVEVIAGGNI  470
            GSYAINP NG  +P+ IADYVLA+YGTGAIMAVP+HD+RDW+FA+ F L I+ V+ GGN+
Sbjct  308  GSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNV  367

Query  471  SESAYTGDGILVNSDYLNGMSVPAAKRAIVDRLESAGRGRARIEFKLRDWLFARQRYWGE  530
             E+A+T DG+ +NSD+L+G+  ++A   +V++LE+ G G   + ++LRDWLF+RQRYWGE
Sbjct  368  EEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGE  427

Query  531  PFPIVYDSDGRPHALDEAALPVELPDVPDYSPVLFdpddadsepsppLAKATEWVHVDLD  590
            P+PI+   DG + A+ E+ LP+ LP   D  P         +   +PLA+ T+W++V  +
Sbjct  428  PIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTDWLEVTRE  479

Query  591  LGDGLKPYSRDTNVMPQWAGSSWYELRYTDPHNSERFCAKENEAYWMGPRPAEHGPDDPG  650
              DG+K   R+TN MPQWAGSSWY LRY DPHN+E++   E    W+             
Sbjct  480  --DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWL-------------  523

Query  651  GVDLYVGGAEHAVLHLLYSRFWHKVLYDLGHVSSREPYRRLVNQGYIQAYAYTDARGSYV  710
             VD+YVGGAEHAVLHLLY+RFWHKVLYDLG V+++EP+++L NQG I + +Y D+RG+ V
Sbjct  524  PVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALV  583

Query  711  PAEQVIERGDRFVYPGPDGEVEVFQEFGKIGKSLKNSVSPDEICDAYGADTLRVYEMSMG  770
            ++++V  R++ F     + E+E  Q  +K++KSLKN V+PD++ + YGADTLRVYEM MG
Sbjct  584  ATDKVEKRDGSFFHVETGEELE--QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMG  641

Query  771  PLEASRPWATKDVVGAYRFLQRVWRLVVDEHTGETRVADGVELDIDTLRALHRTIVGVSE  830
            PL+AS +W+  ++ G+ +FL+RV RL+   +  E    ++  LD    +  + T+ +V+E
Sbjct  642  PLDASIAWSEEGLEGSRKFLDRVYRLITTKEITE---ENSGALD----KVYNETVKAVTE  694

Query  831  DFAALRNNTATAKLIEYTNHLTKKHRDAVPRAAVEPLVQMLAPLAPHIAEELWLRLGNTT  890
            +   ++ NTA A+L+ + N   K ++  +       +VQ++AP+APH++EELW  L  + 
Sbjct  695  QVDQMKFNTAIAQLMVFVNAANKEDK--LFSDYAKGFVQLIAPFAPHLGEELWQALTASG  752

Query  891  -SLAHGPFPKADAAYLVDETVEYPVQVNGKVRGRVVVAADTDEETLKAAVLTDEKVQAFL  949
             S++  P P  D + LV++ VE  VQ++GKV++++VVA D   E L+   L++EKVQA +
Sbjct  753  ESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEI  812

Query  950  AGATPRKVIVVAGRLVNLVI  969
            AG    KVI V+ +LVN+VI
Sbjct  813  AGKDIIKVIAVPNKLVNIVI  832


 Score =  129 bits (474),  Expect = 7e-31, Method: Compositional matrix adjust.
 Identities = 73/148 (50%), Positives = 99/148 (67%), Gaps = 11/148 (7%)

Query  35   LERTWQENWARLGTFNVPNPVGSLAPPDGAAVPDDKLFVQDMFPYPSGEGLHVGHPLGYI  94
            +E  WQ  WA   TF+            G+  +  K++  DMFPYPSG GLHVGHP GY 
Sbjct  9    IEPKWQAFWADNHTFKT-----------GTDASKPKFYALDMFPYPSGAGLHVGHPEGYT  57

Query  95   ATDVYARYFRMVGRNVLHALGFDAFGLPAEQYAVQTGTHPRTRTEANVVNFRRQLGRLGF  154
            ATD+ +R+ R  G+NVLH++G DAFGLPAEQYA++TG +P   T  N+ NF+RQ+  LGF
Sbjct  58   ATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGF  117

Query  155  GHDSRRSFSTTDVDFYRWTQWIFLQIYN  182
            + D  R  +TTD ++Y+WTQWIF ++Y+
Sbjct  118  SYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1526) leuS in NC_008769


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  510 bits (1924),  Expect = 2e-145, Method: Compositional matrix adjust.
 Identities = 349/740 (48%), Positives = 501/740 (68%), Gaps = 57/740 (7%)

Query  232  LVYRADSLVNWCPGLGTVLANEEVTADGRSDRGNFPVFRKRLRQWMMRITAYAdrllddl  291
            L Y A+  VNW   LGT +ANEEV +DG S+RG +PV RK +RQWM++ITAYA+RLL+DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  292  dvldWPEQVKTMQRNWIGRSTGAVALFSARAASDDGFEVDIEVFTTRPDTLFGATYLVLA  351
            + +DWPE +K MQRNWIG+STGA   F  + +     + D+ VFTTRPDTLFGATY VLA
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDT-----DKDFTVFTTRPDTLFGATYAVLA  262

Query  352  PEHDLVDELVAASWPAGVNPLWTYGGGTPGEaiaayrraiaaKSDLERQE-SREKTGVFL  410
            PEH LVD + ++                 +EA+A Y+R  + KSDL R + ++EKTGV  
Sbjct  263  PEHALVDAITTSD---------------QAEAVADYKRQASLKSDLARTDLAKEKTGVWT  307

Query  411  GSYAINPANGEPVPIFIADYVLAGYGTGAIMAVPGHDQRDWDFARAFGLPIVEVIAGGNI  470
            GSYAINP NG  +P+ IADYVLA+YGTGAIMAVP+HD+RDW+FA+ F L I+ V+ GGN+
Sbjct  308  GSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNV  367

Query  471  SESAYTGDGILVNSDYLNGMSVPAAKRAIVDRLESAGRGRARIEFKLRDWLFARQRYWGE  530
             E+A+T DG+ +NSD+L+G+  ++A   +V++LE+ G G   + ++LRDWLF+RQRYWGE
Sbjct  368  EEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGE  427

Query  531  PFPIVYDSDGRPHALDEAALPVELPDVPDYSPVLFdpddadsepsppLAKATEWVHVDLD  590
            P+PI+   DG + A+ E+ LP+ LP   D  P         +   +PLA+ T+W++V  +
Sbjct  428  PIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTDWLEVTRE  479

Query  591  LGDGLKPYSRDTNVMPQWAGSSWYELRYTDPHNSERFCAKENEAYWMGPRPAEHGPDDPG  650
              DG+K   R+TN MPQWAGSSWY LRY DPHN+E++   E    W+             
Sbjct  480  --DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWL-------------  523

Query  651  GVDLYVGGAEHAVLHLLYSRFWHKVLYDLGHVSSREPYRRLVNQGYIQAYAYTDARGSYV  710
             VD+YVGGAEHAVLHLLY+RFWHKVLYDLG V+++EP+++L NQG I + +Y D+RG+ V
Sbjct  524  PVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALV  583

Query  711  PAEQVIERGDRFVYPGPDGEVEVFQEFGKIGKSLKNSVSPDEICDAYGADTLRVYEMSMG  770
            ++++V  R++ F     + E+E  Q  +K++KSLKN V+PD++ + YGADTLRVYEM MG
Sbjct  584  ATDKVEKRDGSFFHVETGEELE--QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMG  641

Query  771  PLEASRPWATKDVVGAYRFLQRVWRLVVDEHTGETRVADGVELDIDTLRALHRTIVGVSE  830
            PL+AS +W+  ++ G+ +FL+RV RL+   +  E    ++  LD    +  + T+ +V+E
Sbjct  642  PLDASIAWSEEGLEGSRKFLDRVYRLITTKEITE---ENSGALD----KVYNETVKAVTE  694

Query  831  DFAALRNNTATAKLIEYTNHLTKKHRDAVPRAAVEPLVQMLAPLAPHIAEELWLRLGNTT  890
            +   ++ NTA A+L+ + N   K ++  +       +VQ++AP+APH++EELW  L  + 
Sbjct  695  QVDQMKFNTAIAQLMVFVNAANKEDK--LFSDYAKGFVQLIAPFAPHLGEELWQALTASG  752

Query  891  -SLAHGPFPKADAAYLVDETVEYPVQVNGKVRGRVVVAADTDEETLKAAVLTDEKVQAFL  949
             S++  P P  D + LV++ VE  VQ++GKV++++VVA D   E L+   L++EKVQA +
Sbjct  753  ESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEI  812

Query  950  AGATPRKVIVVAGRLVNLVI  969
            AG    KVI V+ +LVN+VI
Sbjct  813  AGKDIIKVIAVPNKLVNIVI  832


 Score =  129 bits (474),  Expect = 7e-31, Method: Compositional matrix adjust.
 Identities = 73/148 (50%), Positives = 99/148 (67%), Gaps = 11/148 (7%)

Query  35   LERTWQENWARLGTFNVPNPVGSLAPPDGAAVPDDKLFVQDMFPYPSGEGLHVGHPLGYI  94
            +E  WQ  WA   TF+            G+  +  K++  DMFPYPSG GLHVGHP GY 
Sbjct  9    IEPKWQAFWADNHTFKT-----------GTDASKPKFYALDMFPYPSGAGLHVGHPEGYT  57

Query  95   ATDVYARYFRMVGRNVLHALGFDAFGLPAEQYAVQTGTHPRTRTEANVVNFRRQLGRLGF  154
            ATD+ +R+ R  G+NVLH++G DAFGLPAEQYA++TG +P   T  N+ NF+RQ+  LGF
Sbjct  58   ATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGF  117

Query  155  GHDSRRSFSTTDVDFYRWTQWIFLQIYN  182
            + D  R  +TTD ++Y+WTQWIF ++Y+
Sbjct  118  SYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1527) leuS in NC_012207


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  510 bits (1924),  Expect = 2e-145, Method: Compositional matrix adjust.
 Identities = 349/740 (48%), Positives = 501/740 (68%), Gaps = 57/740 (7%)

Query  232  LVYRADSLVNWCPGLGTVLANEEVTADGRSDRGNFPVFRKRLRQWMMRITAYAdrllddl  291
            L Y A+  VNW   LGT +ANEEV +DG S+RG +PV RK +RQWM++ITAYA+RLL+DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  292  dvldWPEQVKTMQRNWIGRSTGAVALFSARAASDDGFEVDIEVFTTRPDTLFGATYLVLA  351
            + +DWPE +K MQRNWIG+STGA   F  + +     + D+ VFTTRPDTLFGATY VLA
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDT-----DKDFTVFTTRPDTLFGATYAVLA  262

Query  352  PEHDLVDELVAASWPAGVNPLWTYGGGTPGEaiaayrraiaaKSDLERQE-SREKTGVFL  410
            PEH LVD + ++                 +EA+A Y+R  + KSDL R + ++EKTGV  
Sbjct  263  PEHALVDAITTSD---------------QAEAVADYKRQASLKSDLARTDLAKEKTGVWT  307

Query  411  GSYAINPANGEPVPIFIADYVLAGYGTGAIMAVPGHDQRDWDFARAFGLPIVEVIAGGNI  470
            GSYAINP NG  +P+ IADYVLA+YGTGAIMAVP+HD+RDW+FA+ F L I+ V+ GGN+
Sbjct  308  GSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNV  367

Query  471  SESAYTGDGILVNSDYLNGMSVPAAKRAIVDRLESAGRGRARIEFKLRDWLFARQRYWGE  530
             E+A+T DG+ +NSD+L+G+  ++A   +V++LE+ G G   + ++LRDWLF+RQRYWGE
Sbjct  368  EEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGE  427

Query  531  PFPIVYDSDGRPHALDEAALPVELPDVPDYSPVLFdpddadsepsppLAKATEWVHVDLD  590
            P+PI+   DG + A+ E+ LP+ LP   D  P         +   +PLA+ T+W++V  +
Sbjct  428  PIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTDWLEVTRE  479

Query  591  LGDGLKPYSRDTNVMPQWAGSSWYELRYTDPHNSERFCAKENEAYWMGPRPAEHGPDDPG  650
              DG+K   R+TN MPQWAGSSWY LRY DPHN+E++   E    W+             
Sbjct  480  --DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWL-------------  523

Query  651  GVDLYVGGAEHAVLHLLYSRFWHKVLYDLGHVSSREPYRRLVNQGYIQAYAYTDARGSYV  710
             VD+YVGGAEHAVLHLLY+RFWHKVLYDLG V+++EP+++L NQG I + +Y D+RG+ V
Sbjct  524  PVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALV  583

Query  711  PAEQVIERGDRFVYPGPDGEVEVFQEFGKIGKSLKNSVSPDEICDAYGADTLRVYEMSMG  770
            ++++V  R++ F     + E+E  Q  +K++KSLKN V+PD++ + YGADTLRVYEM MG
Sbjct  584  ATDKVEKRDGSFFHVETGEELE--QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMG  641

Query  771  PLEASRPWATKDVVGAYRFLQRVWRLVVDEHTGETRVADGVELDIDTLRALHRTIVGVSE  830
            PL+AS +W+  ++ G+ +FL+RV RL+   +  E    ++  LD    +  + T+ +V+E
Sbjct  642  PLDASIAWSEEGLEGSRKFLDRVYRLITTKEITE---ENSGALD----KVYNETVKAVTE  694

Query  831  DFAALRNNTATAKLIEYTNHLTKKHRDAVPRAAVEPLVQMLAPLAPHIAEELWLRLGNTT  890
            +   ++ NTA A+L+ + N   K ++  +       +VQ++AP+APH++EELW  L  + 
Sbjct  695  QVDQMKFNTAIAQLMVFVNAANKEDK--LFSDYAKGFVQLIAPFAPHLGEELWQALTASG  752

Query  891  -SLAHGPFPKADAAYLVDETVEYPVQVNGKVRGRVVVAADTDEETLKAAVLTDEKVQAFL  949
             S++  P P  D + LV++ VE  VQ++GKV++++VVA D   E L+   L++EKVQA +
Sbjct  753  ESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEI  812

Query  950  AGATPRKVIVVAGRLVNLVI  969
            AG    KVI V+ +LVN+VI
Sbjct  813  AGKDIIKVIAVPNKLVNIVI  832


 Score =  129 bits (474),  Expect = 7e-31, Method: Compositional matrix adjust.
 Identities = 73/148 (50%), Positives = 99/148 (67%), Gaps = 11/148 (7%)

Query  35   LERTWQENWARLGTFNVPNPVGSLAPPDGAAVPDDKLFVQDMFPYPSGEGLHVGHPLGYI  94
            +E  WQ  WA   TF+            G+  +  K++  DMFPYPSG GLHVGHP GY 
Sbjct  9    IEPKWQAFWADNHTFKT-----------GTDASKPKFYALDMFPYPSGAGLHVGHPEGYT  57

Query  95   ATDVYARYFRMVGRNVLHALGFDAFGLPAEQYAVQTGTHPRTRTEANVVNFRRQLGRLGF  154
            ATD+ +R+ R  G+NVLH++G DAFGLPAEQYA++TG +P   T  N+ NF+RQ+  LGF
Sbjct  58   ATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGF  117

Query  155  GHDSRRSFSTTDVDFYRWTQWIFLQIYN  182
            + D  R  +TTD ++Y+WTQWIF ++Y+
Sbjct  118  SYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1528) leuS in NC_015848


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  510 bits (1924),  Expect = 2e-145, Method: Compositional matrix adjust.
 Identities = 349/740 (48%), Positives = 501/740 (68%), Gaps = 57/740 (7%)

Query  232  LVYRADSLVNWCPGLGTVLANEEVTADGRSDRGNFPVFRKRLRQWMMRITAYAdrllddl  291
            L Y A+  VNW   LGT +ANEEV +DG S+RG +PV RK +RQWM++ITAYA+RLL+DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  292  dvldWPEQVKTMQRNWIGRSTGAVALFSARAASDDGFEVDIEVFTTRPDTLFGATYLVLA  351
            + +DWPE +K MQRNWIG+STGA   F  + +     + D+ VFTTRPDTLFGATY VLA
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDT-----DKDFTVFTTRPDTLFGATYAVLA  262

Query  352  PEHDLVDELVAASWPAGVNPLWTYGGGTPGEaiaayrraiaaKSDLERQE-SREKTGVFL  410
            PEH LVD + ++                 +EA+A Y+R  + KSDL R + ++EKTGV  
Sbjct  263  PEHALVDAITTSD---------------QAEAVADYKRQASLKSDLARTDLAKEKTGVWT  307

Query  411  GSYAINPANGEPVPIFIADYVLAGYGTGAIMAVPGHDQRDWDFARAFGLPIVEVIAGGNI  470
            GSYAINP NG  +P+ IADYVLA+YGTGAIMAVP+HD+RDW+FA+ F L I+ V+ GGN+
Sbjct  308  GSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNV  367

Query  471  SESAYTGDGILVNSDYLNGMSVPAAKRAIVDRLESAGRGRARIEFKLRDWLFARQRYWGE  530
             E+A+T DG+ +NSD+L+G+  ++A   +V++LE+ G G   + ++LRDWLF+RQRYWGE
Sbjct  368  EEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGE  427

Query  531  PFPIVYDSDGRPHALDEAALPVELPDVPDYSPVLFdpddadsepsppLAKATEWVHVDLD  590
            P+PI+   DG + A+ E+ LP+ LP   D  P         +   +PLA+ T+W++V  +
Sbjct  428  PIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTDWLEVTRE  479

Query  591  LGDGLKPYSRDTNVMPQWAGSSWYELRYTDPHNSERFCAKENEAYWMGPRPAEHGPDDPG  650
              DG+K   R+TN MPQWAGSSWY LRY DPHN+E++   E    W+             
Sbjct  480  --DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWL-------------  523

Query  651  GVDLYVGGAEHAVLHLLYSRFWHKVLYDLGHVSSREPYRRLVNQGYIQAYAYTDARGSYV  710
             VD+YVGGAEHAVLHLLY+RFWHKVLYDLG V+++EP+++L NQG I + +Y D+RG+ V
Sbjct  524  PVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALV  583

Query  711  PAEQVIERGDRFVYPGPDGEVEVFQEFGKIGKSLKNSVSPDEICDAYGADTLRVYEMSMG  770
            ++++V  R++ F     + E+E  Q  +K++KSLKN V+PD++ + YGADTLRVYEM MG
Sbjct  584  ATDKVEKRDGSFFHVETGEELE--QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMG  641

Query  771  PLEASRPWATKDVVGAYRFLQRVWRLVVDEHTGETRVADGVELDIDTLRALHRTIVGVSE  830
            PL+AS +W+  ++ G+ +FL+RV RL+   +  E    ++  LD    +  + T+ +V+E
Sbjct  642  PLDASIAWSEEGLEGSRKFLDRVYRLITTKEITE---ENSGALD----KVYNETVKAVTE  694

Query  831  DFAALRNNTATAKLIEYTNHLTKKHRDAVPRAAVEPLVQMLAPLAPHIAEELWLRLGNTT  890
            +   ++ NTA A+L+ + N   K ++  +       +VQ++AP+APH++EELW  L  + 
Sbjct  695  QVDQMKFNTAIAQLMVFVNAANKEDK--LFSDYAKGFVQLIAPFAPHLGEELWQALTASG  752

Query  891  -SLAHGPFPKADAAYLVDETVEYPVQVNGKVRGRVVVAADTDEETLKAAVLTDEKVQAFL  949
             S++  P P  D + LV++ VE  VQ++GKV++++VVA D   E L+   L++EKVQA +
Sbjct  753  ESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEI  812

Query  950  AGATPRKVIVVAGRLVNLVI  969
            AG    KVI V+ +LVN+VI
Sbjct  813  AGKDIIKVIAVPNKLVNIVI  832


 Score =  129 bits (474),  Expect = 7e-31, Method: Compositional matrix adjust.
 Identities = 73/148 (50%), Positives = 99/148 (67%), Gaps = 11/148 (7%)

Query  35   LERTWQENWARLGTFNVPNPVGSLAPPDGAAVPDDKLFVQDMFPYPSGEGLHVGHPLGYI  94
            +E  WQ  WA   TF+            G+  +  K++  DMFPYPSG GLHVGHP GY 
Sbjct  9    IEPKWQAFWADNHTFKT-----------GTDASKPKFYALDMFPYPSGAGLHVGHPEGYT  57

Query  95   ATDVYARYFRMVGRNVLHALGFDAFGLPAEQYAVQTGTHPRTRTEANVVNFRRQLGRLGF  154
            ATD+ +R+ R  G+NVLH++G DAFGLPAEQYA++TG +P   T  N+ NF+RQ+  LGF
Sbjct  58   ATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGF  117

Query  155  GHDSRRSFSTTDVDFYRWTQWIFLQIYN  182
            + D  R  +TTD ++Y+WTQWIF ++Y+
Sbjct  118  SYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1529) leuS in NC_019950


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  510 bits (1924),  Expect = 2e-145, Method: Compositional matrix adjust.
 Identities = 349/740 (48%), Positives = 501/740 (68%), Gaps = 57/740 (7%)

Query  232  LVYRADSLVNWCPGLGTVLANEEVTADGRSDRGNFPVFRKRLRQWMMRITAYAdrllddl  291
            L Y A+  VNW   LGT +ANEEV +DG S+RG +PV RK +RQWM++ITAYA+RLL+DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  292  dvldWPEQVKTMQRNWIGRSTGAVALFSARAASDDGFEVDIEVFTTRPDTLFGATYLVLA  351
            + +DWPE +K MQRNWIG+STGA   F  + +     + D+ VFTTRPDTLFGATY VLA
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDT-----DKDFTVFTTRPDTLFGATYAVLA  262

Query  352  PEHDLVDELVAASWPAGVNPLWTYGGGTPGEaiaayrraiaaKSDLERQE-SREKTGVFL  410
            PEH LVD + ++                 +EA+A Y+R  + KSDL R + ++EKTGV  
Sbjct  263  PEHALVDAITTSD---------------QAEAVADYKRQASLKSDLARTDLAKEKTGVWT  307

Query  411  GSYAINPANGEPVPIFIADYVLAGYGTGAIMAVPGHDQRDWDFARAFGLPIVEVIAGGNI  470
            GSYAINP NG  +P+ IADYVLA+YGTGAIMAVP+HD+RDW+FA+ F L I+ V+ GGN+
Sbjct  308  GSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNV  367

Query  471  SESAYTGDGILVNSDYLNGMSVPAAKRAIVDRLESAGRGRARIEFKLRDWLFARQRYWGE  530
             E+A+T DG+ +NSD+L+G+  ++A   +V++LE+ G G   + ++LRDWLF+RQRYWGE
Sbjct  368  EEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGE  427

Query  531  PFPIVYDSDGRPHALDEAALPVELPDVPDYSPVLFdpddadsepsppLAKATEWVHVDLD  590
            P+PI+   DG + A+ E+ LP+ LP   D  P         +   +PLA+ T+W++V  +
Sbjct  428  PIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTDWLEVTRE  479

Query  591  LGDGLKPYSRDTNVMPQWAGSSWYELRYTDPHNSERFCAKENEAYWMGPRPAEHGPDDPG  650
              DG+K   R+TN MPQWAGSSWY LRY DPHN+E++   E    W+             
Sbjct  480  --DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWL-------------  523

Query  651  GVDLYVGGAEHAVLHLLYSRFWHKVLYDLGHVSSREPYRRLVNQGYIQAYAYTDARGSYV  710
             VD+YVGGAEHAVLHLLY+RFWHKVLYDLG V+++EP+++L NQG I + +Y D+RG+ V
Sbjct  524  PVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALV  583

Query  711  PAEQVIERGDRFVYPGPDGEVEVFQEFGKIGKSLKNSVSPDEICDAYGADTLRVYEMSMG  770
            ++++V  R++ F     + E+E  Q  +K++KSLKN V+PD++ + YGADTLRVYEM MG
Sbjct  584  ATDKVEKRDGSFFHVETGEELE--QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMG  641

Query  771  PLEASRPWATKDVVGAYRFLQRVWRLVVDEHTGETRVADGVELDIDTLRALHRTIVGVSE  830
            PL+AS +W+  ++ G+ +FL+RV RL+   +  E    ++  LD    +  + T+ +V+E
Sbjct  642  PLDASIAWSEEGLEGSRKFLDRVYRLITTKEITE---ENSGALD----KVYNETVKAVTE  694

Query  831  DFAALRNNTATAKLIEYTNHLTKKHRDAVPRAAVEPLVQMLAPLAPHIAEELWLRLGNTT  890
            +   ++ NTA A+L+ + N   K ++  +       +VQ++AP+APH++EELW  L  + 
Sbjct  695  QVDQMKFNTAIAQLMVFVNAANKEDK--LFSDYAKGFVQLIAPFAPHLGEELWQALTASG  752

Query  891  -SLAHGPFPKADAAYLVDETVEYPVQVNGKVRGRVVVAADTDEETLKAAVLTDEKVQAFL  949
             S++  P P  D + LV++ VE  VQ++GKV++++VVA D   E L+   L++EKVQA +
Sbjct  753  ESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEI  812

Query  950  AGATPRKVIVVAGRLVNLVI  969
            AG    KVI V+ +LVN+VI
Sbjct  813  AGKDIIKVIAVPNKLVNIVI  832


 Score =  129 bits (474),  Expect = 7e-31, Method: Compositional matrix adjust.
 Identities = 73/148 (50%), Positives = 99/148 (67%), Gaps = 11/148 (7%)

Query  35   LERTWQENWARLGTFNVPNPVGSLAPPDGAAVPDDKLFVQDMFPYPSGEGLHVGHPLGYI  94
            +E  WQ  WA   TF+            G+  +  K++  DMFPYPSG GLHVGHP GY 
Sbjct  9    IEPKWQAFWADNHTFKT-----------GTDASKPKFYALDMFPYPSGAGLHVGHPEGYT  57

Query  95   ATDVYARYFRMVGRNVLHALGFDAFGLPAEQYAVQTGTHPRTRTEANVVNFRRQLGRLGF  154
            ATD+ +R+ R  G+NVLH++G DAFGLPAEQYA++TG +P   T  N+ NF+RQ+  LGF
Sbjct  58   ATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGF  117

Query  155  GHDSRRSFSTTDVDFYRWTQWIFLQIYN  182
            + D  R  +TTD ++Y+WTQWIF ++Y+
Sbjct  118  SYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1530) leuS in NC_019965


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  510 bits (1924),  Expect = 2e-145, Method: Compositional matrix adjust.
 Identities = 349/740 (48%), Positives = 501/740 (68%), Gaps = 57/740 (7%)

Query  232  LVYRADSLVNWCPGLGTVLANEEVTADGRSDRGNFPVFRKRLRQWMMRITAYAdrllddl  291
            L Y A+  VNW   LGT +ANEEV +DG S+RG +PV RK +RQWM++ITAYA+RLL+DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  292  dvldWPEQVKTMQRNWIGRSTGAVALFSARAASDDGFEVDIEVFTTRPDTLFGATYLVLA  351
            + +DWPE +K MQRNWIG+STGA   F  + +     + D+ VFTTRPDTLFGATY VLA
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDT-----DKDFTVFTTRPDTLFGATYAVLA  262

Query  352  PEHHLVDELVAASWPAGVNPLWTYGGGTPGEaiaayrraiaaKSDLERQE-SREKTGVFL  410
            PEH LVD + ++                 +EA+A Y+R  + KSDL R + ++EKTGV  
Sbjct  263  PEHALVDAITTSD---------------QAEAVADYKRQASLKSDLARTDLAKEKTGVWT  307

Query  411  GSYAINPANGEPVPIFIADYVLAGYGTGAIMAVPGHDQRDWDFARAFGLPIVEVIAGGNI  470
            GSYAINP NG  +P+ IADYVLA+YGTGAIMAVP+HD+RDW+FA+ F L I+ V+ GGN+
Sbjct  308  GSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNV  367

Query  471  SESAYTGDGILVNSDYLNGMSVPAAKRAIVDRLESAGRGRARIEFKLRDWLFARQRYWGE  530
             E+A+T DG+ +NSD+L+G+  ++A   +V++LE+ G G   + ++LRDWLF+RQRYWGE
Sbjct  368  EEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGE  427

Query  531  PFPIVYDSDGRPHALDEAALPVELPDVPDYSPVLFdpddadsepsppLAKATEWVHVDLD  590
            P+PI+   DG + A+ E+ LP+ LP   D  P         +   +PLA+ T+W++V  +
Sbjct  428  PIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTDWLEVTRE  479

Query  591  LGDGLKPYSRDTNVMPQWAGSSWYELRYTDPHNSERFCAKENEAYWMGPRPAEHGPDDPG  650
              DG+K   R+TN MPQWAGSSWY LRY DPHN+E++   E    W+             
Sbjct  480  --DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWL-------------  523

Query  651  GVDLYVGGAEHAVLHLLYSRFWHKVLYDLGHVSSREPYRRLVNQGYIQAYAYTDARGSYV  710
             VD+YVGGAEHAVLHLLY+RFWHKVLYDLG V+++EP+++L NQG I + +Y D+RG+ V
Sbjct  524  PVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALV  583

Query  711  PAEQVIERGDRFVYPGPDGEVEVFQEFGKIGKSLKNSVSPDEICDAYGADTLRVYEMSMG  770
            ++++V  R++ F     + E+E  Q  +K++KSLKN V+PD++ + YGADTLRVYEM MG
Sbjct  584  ATDKVEKRDGSFFHVETGEELE--QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMG  641

Query  771  PLEASRPWATKDVVGAYRFLQRVWRLVVDEHTGETRVADGVELDIDTLRALHRTIVGVSE  830
            PL+AS +W+  ++ G+ +FL+RV RL+   +  E    ++  LD    +  + T+ +V+E
Sbjct  642  PLDASIAWSEEGLEGSRKFLDRVYRLITTKEITE---ENSGALD----KVYNETVKAVTE  694

Query  831  DFAALRNNTATAKLIEYTNHLTKKHRDAVPRAAVEPLVQMLAPLAPHIAEELWLRLGNTT  890
            +   ++ NTA A+L+ + N   K ++  +       +VQ++AP+APH++EELW  L  + 
Sbjct  695  QVDQMKFNTAIAQLMVFVNAANKEDK--LFSDYAKGFVQLIAPFAPHLGEELWQALTASG  752

Query  891  -SLAHGPFPKADAAYLVDETVEYPVQVNGKVRGRVVVAADTDEETLKAAVLTDEKVQAFL  949
             S++  P P  D + LV++ VE  VQ++GKV++++VVA D   E L+   L++EKVQA +
Sbjct  753  ESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEI  812

Query  950  AGATPRKVIVVAGRLVNLVI  969
            AG    KVI V+ +LVN+VI
Sbjct  813  AGKDIIKVIAVPNKLVNIVI  832


 Score =  129 bits (474),  Expect = 7e-31, Method: Compositional matrix adjust.
 Identities = 73/148 (50%), Positives = 99/148 (67%), Gaps = 11/148 (7%)

Query  35   LERTWQENWARLGTFNVPNPVGSLAPPDGAAVPDDKLFVQDMFPYPSGEGLHVGHPLGYI  94
            +E  WQ  WA   TF+            G+  +  K++  DMFPYPSG GLHVGHP GY 
Sbjct  9    IEPKWQAFWADNHTFKT-----------GTDASKPKFYALDMFPYPSGAGLHVGHPEGYT  57

Query  95   ATDVYARYFRMVGRNVLHALGFDAFGLPAEQYAVQTGTHPRTRTEANVVNFRRQLGRLGF  154
            ATD+ +R+ R  G+NVLH++G DAFGLPAEQYA++TG +P   T  N+ NF+RQ+  LGF
Sbjct  58   ATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGF  117

Query  155  GHDSRRSFSTTDVDFYRWTQWIFLQIYN  182
            + D  R  +TTD ++Y+WTQWIF ++Y+
Sbjct  118  SYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1531) leuS in NC_009338


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  510 bits (1924),  Expect = 2e-145, Method: Compositional matrix adjust.
 Identities = 346/732 (48%), Positives = 489/732 (67%), Gaps = 51/732 (6%)

Query  222  LVYLADSVVNWCPGLGTVLANEEVTADGRSERGNFPVFRKRLRQWMMRITAYSDRLLEDL  281
            L Y A+  VNW   LGT +ANEEV +DG SERG +PV RK +RQWM++ITAY++RLLEDL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  282  DVLDWPDKVKTMQRNWIGRSTGAEVQFSTAAGDIE--VFTTRPDTLFGATYMVLAPEHDL  339
            + +DWP+ +K MQRNWIG+STGA+V F     D +  VFTTRPDTLFGATY VLAPEH L
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  340  VDRLVASAWPDGTDARWTFGAATPAEAVAAYRAGIAAKSDLERQE-NKTKTGVFLGAYAT  398
            VD               ++ ++  AEAVA Y+   + KSDL R +  K KTGV  G+YA 
Sbjct  268  VD---------------AITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAI  312

Query  399  NPANGQQVPVFIADYVLAGYGTGAIMAVPSGDQRDWDFATEFGLPIVEVVAGGDVTVEAY  458
            NP NG+++PV IADYVLA+YGTGAIMAVP+ D+RDW+FA +F L I+ V+ GG+V   A+
Sbjct  313  NPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEAAF  372

Query  459  SGDGTMVNSGFLDGMDVATAKQAMTERLVADGRGRARVEYKLRDWLFARQRYWGEPFPVV  518
            + DG  +NS+FLDG+D A+A   M E+L A+G G   V Y+LRDWLF+RQRYWGEP+P++
Sbjct  373  TEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPII  432

Query  519  YDSEGRAHGLPEGMLPVELPDVPDYSPVSFDPDDAGSEPSPPLGKVTDWVNVDLDLGDGL  578
               +G + ++PE+ LP+ LP   D  P        ++   +PL++VTDW++V  +  DG+
Sbjct  433  HWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTDWLEVTRE--DGV  482

Query  579  KPYTRDTNVMPQWAGSSWYELRYTDPYNSEALCAKENEAYWMGPRPAEHGPDDPGGVDLY  638
            K   R+TN MPQWAGSSWY LRY DP N+E L   E    W+              VD+Y
Sbjct  483  KG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWL-------------PVDIY  528

Query  639  VGGVEHAVLHLLYSRFWHKVLYDLGHVSSREPYRRLVNQGYIQAFAYTDSRGSYVPAAEV  698
            VGG EHAVLHLLY+RFWHKVLYDLG V+++EP+++L NQG I + +Y DSRG+ V++  V
Sbjct  529  VGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKV  588

Query  699  IERDGKFVWPGPDGETEVNQEFGKIGKSLKNSVSPDEICDNYGADTLRVYEMSMGPLEAS  758
              RDG F     +   E++Q  +K++KSLKN V+PD++ ++YGADTLRVYEM MGPL+AS
Sbjct  589  EKRDGSFF--HVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  759  RPWATKDVVGAYRFLQRVWRLVVDENTGetlatedaldddtlrllhrtIAGTADDYASLR  818
             +W+  ++ G+ +FL+RV RL+   +        +   +   ++ + T+ + +++   ++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLITTKEIT------EENSGALDKVYNETVKAVTEQVDQMK  700

Query  819  NNTAAAKLIEYTNHLTKQSVTARAALEPLVLMVAPLAPHLAEELWKRLGHEG-SLAHGPF  877
             NTA A+L+ + N   K+          +V ++AP+APHL+EELW+ L   G S++  P 
Sbjct  701  FNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPW  760

Query  878  PLADERYLVEDTVEYPVQVNGKVRGRVTvpadapadaveaaalaeekvvaFLDGRTPKKV  937
            P  DE  LVE+ VE  VQ++GKV++++ V+ D + + ++  ALA+EKV A + G+   KV
Sbjct  761  PSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKV  820

Query  938  IVVAGRLVNVVV  949
            I V+ +LVN+V+
Sbjct  821  IAVPNKLVNIVI  832


 Score =  130 bits (475),  Expect = 6e-31, Method: Compositional matrix adjust.
 Identities = 76/148 (52%), Positives = 98/148 (67%), Gaps = 11/148 (7%)

Query  25   IERAWQQQWADSGTFHVDNPVGSLAPADGSAVPADKMFVQDMFPYPSGEGLHVGHPLGYI  84
            IE  WQ  WAD+ TF             G+  +  K +  DMFPYPSG GLHVGHP GY 
Sbjct  9    IEPKWQAFWADNHTFKT-----------GTDASKPKFYALDMFPYPSGAGLHVGHPEGYT  57

Query  85   ATDVYARYYRMTGRNVLHALGFDAFGLPAEQYAIQTGTHPRTRTEANIVNFRRQLGRLGL  144
            ATD+ +R+ R  G+NVLH++G DAFGLPAEQYA++TG +P   T  NI NF+RQ+  LG+
Sbjct  58   ATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGF  117

Query  145  GHDSRRSFATTDVDYYKWTQWIFLQIFN  172
            + D  R   TTD +YYKWTQWIF ++++
Sbjct  118  SYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1532) leuS in NC_021193


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  510 bits (1924),  Expect = 2e-145, Method: Compositional matrix adjust.
 Identities = 349/740 (48%), Positives = 501/740 (68%), Gaps = 57/740 (7%)

Query  232  LVYRADSLVNWCPGLGTVLANEEVTADGRSDRGNFPVFRKRLRQWMMRITAYAdrllddl  291
            L Y A+  VNW   LGT +ANEEV +DG S+RG +PV RK +RQWM++ITAYA+RLL+DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  292  dvldWPEQVKTMQRNWIGRSTGAVALFSARAASDDGFEVDIEVFTTRPDTLFGATYLVLA  351
            + +DWPE +K MQRNWIG+STGA   F  + +     + D+ VFTTRPDTLFGATY VLA
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDT-----DKDFTVFTTRPDTLFGATYAVLA  262

Query  352  PEHDLVDELVAASWPAGVNPLWTYGGGTPGEaiaayrraiaaKSDLERQE-SREKTGVFL  410
            PEH LVD + ++                 +EA+A Y+R  + KSDL R + ++EKTGV  
Sbjct  263  PEHALVDAITTSD---------------QAEAVADYKRQASLKSDLARTDLAKEKTGVWT  307

Query  411  GSYAINPANGEPVPIFIADYVLAGYGTGAIMAVPGHDQRDWDFARAFGLPIVEVIAGGNI  470
            GSYAINP NG  +P+ IADYVLA+YGTGAIMAVP+HD+RDW+FA+ F L I+ V+ GGN+
Sbjct  308  GSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNV  367

Query  471  SESAYTGDGILVNSDYLNGMSVPAAKRAIVDRLESAGRGRARIEFKLRDWLFARQRYWGE  530
             E+A+T DG+ +NSD+L+G+  ++A   +V++LE+ G G   + ++LRDWLF+RQRYWGE
Sbjct  368  EEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGE  427

Query  531  PFPIVYDSDGRPHALDEAALPVELPDVPDYSPVLFdpddadsepsppLAKATEWVHVDLD  590
            P+PI+   DG + A+ E+ LP+ LP   D  P         +   +PLA+ T+W++V  +
Sbjct  428  PIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTDWLEVTRE  479

Query  591  LGDGLKPYSRDTNVMPQWAGSSWYELRYTDPHNSERFCAKENEAYWMGPRPAEHGPDDPG  650
              DG+K   R+TN MPQWAGSSWY LRY DPHN+E++   E    W+             
Sbjct  480  --DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWL-------------  523

Query  651  GVDLYVGGAEHAVLHLLYSRFWHKVLYDLGHVSSREPYRRLVNQGYIQAYAYTDARGSYV  710
             VD+YVGGAEHAVLHLLY+RFWHKVLYDLG V+++EP+++L NQG I + +Y D+RG+ V
Sbjct  524  PVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALV  583

Query  711  PAEQVIERGDRFVYPGPDGEVEVFQEFGKIGKSLKNSVSPDEICDAYGADTLRVYEMSMG  770
            ++++V  R++ F     + E+E  Q  +K++KSLKN V+PD++ + YGADTLRVYEM MG
Sbjct  584  ATDKVEKRDGSFFHVETGEELE--QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMG  641

Query  771  PLEASRPWATKDVVGAYRFLQRVWRLVVDEHTGETRVADGVELDIDTLRALHRTIVGVSE  830
            PL+AS +W+  ++ G+ +FL+RV RL+   +  E    ++  LD    +  + T+ +V+E
Sbjct  642  PLDASIAWSEEGLEGSRKFLDRVYRLITTKEITE---ENSGALD----KVYNETVKAVTE  694

Query  831  DFAALRNNTATAKLIEYTNHLTKKHRDAVPRAAVEPLVQMLAPLAPHIAEELWLRLGNTT  890
            +   ++ NTA A+L+ + N   K ++  +       +VQ++AP+APH++EELW  L  + 
Sbjct  695  QVDQMKFNTAIAQLMVFVNAANKEDK--LFSDYAKGFVQLIAPFAPHLGEELWQALTASG  752

Query  891  -SLAHGPFPKADAAYLVDETVEYPVQVNGKVRGRVVVAADTDEETLKAAVLTDEKVQAFL  949
             S++  P P  D + LV++ VE  VQ++GKV++++VVA D   E L+   L++EKVQA +
Sbjct  753  ESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEI  812

Query  950  AGATPRKVIVVAGRLVNLVI  969
            AG    KVI V+ +LVN+VI
Sbjct  813  AGKDIIKVIAVPNKLVNIVI  832


 Score =  129 bits (474),  Expect = 7e-31, Method: Compositional matrix adjust.
 Identities = 73/148 (50%), Positives = 99/148 (67%), Gaps = 11/148 (7%)

Query  35   LERTWQENWARLGTFNVPNPVGSLAPPDGAAVPDDKLFVQDMFPYPSGEGLHVGHPLGYI  94
            +E  WQ  WA   TF+            G+  +  K++  DMFPYPSG GLHVGHP GY 
Sbjct  9    IEPKWQAFWADNHTFKT-----------GTDASKPKFYALDMFPYPSGAGLHVGHPEGYT  57

Query  95   ATDVYARYFRMVGRNVLHALGFDAFGLPAEQYAVQTGTHPRTRTEANVVNFRRQLGRLGF  154
            ATD+ +R+ R  G+NVLH++G DAFGLPAEQYA++TG +P   T  N+ NF+RQ+  LGF
Sbjct  58   ATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGF  117

Query  155  GHDSRRSFSTTDVDFYRWTQWIFLQIYN  182
            + D  R  +TTD ++Y+WTQWIF ++Y+
Sbjct  118  SYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1533) leuS in NC_002755


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  510 bits (1924),  Expect = 2e-145, Method: Compositional matrix adjust.
 Identities = 349/740 (48%), Positives = 501/740 (68%), Gaps = 57/740 (7%)

Query  232  LVYRADSLVNWCPGLGTVLANEEVTADGRSDRGNFPVFRKRLRQWMMRITAYAdrllddl  291
            L Y A+  VNW   LGT +ANEEV +DG S+RG +PV RK +RQWM++ITAYA+RLL+DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  292  dvldWPEQVKTMQRNWIGRSTGAVALFSARAASDDGFEVDIEVFTTRPDTLFGATYLVLA  351
            + +DWPE +K MQRNWIG+STGA   F  + +     + D+ VFTTRPDTLFGATY VLA
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDT-----DKDFTVFTTRPDTLFGATYAVLA  262

Query  352  PEHDLVDELVAASWPAGVNPLWTYGGGTPGEaiaayrraiaaKSDLERQE-SREKTGVFL  410
            PEH LVD + ++                 +EA+A Y+R  + KSDL R + ++EKTGV  
Sbjct  263  PEHALVDAITTSD---------------QAEAVADYKRQASLKSDLARTDLAKEKTGVWT  307

Query  411  GSYAINPANGEPVPIFIADYVLAGYGTGAIMAVPGHDQRDWDFARAFGLPIVEVIAGGNI  470
            GSYAINP NG  +P+ IADYVLA+YGTGAIMAVP+HD+RDW+FA+ F L I+ V+ GGN+
Sbjct  308  GSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNV  367

Query  471  SESAYTGDGILVNSDYLNGMSVPAAKRAIVDRLESAGRGRARIEFKLRDWLFARQRYWGE  530
             E+A+T DG+ +NSD+L+G+  ++A   +V++LE+ G G   + ++LRDWLF+RQRYWGE
Sbjct  368  EEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGE  427

Query  531  PFPIVYDSDGRPHALDEAALPVELPDVPDYSPVLFdpddadsepsppLAKATEWVHVDLD  590
            P+PI+   DG + A+ E+ LP+ LP   D  P         +   +PLA+ T+W++V  +
Sbjct  428  PIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTDWLEVTRE  479

Query  591  LGDGLKPYSRDTNVMPQWAGSSWYELRYTDPHNSERFCAKENEAYWMGPRPAEHGPDDPG  650
              DG+K   R+TN MPQWAGSSWY LRY DPHN+E++   E    W+             
Sbjct  480  --DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWL-------------  523

Query  651  GVDLYVGGAEHAVLHLLYSRFWHKVLYDLGHVSSREPYRRLVNQGYIQAYAYTDARGSYV  710
             VD+YVGGAEHAVLHLLY+RFWHKVLYDLG V+++EP+++L NQG I + +Y D+RG+ V
Sbjct  524  PVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALV  583

Query  711  PAEQVIERGDRFVYPGPDGEVEVFQEFGKIGKSLKNSVSPDEICDAYGADTLRVYEMSMG  770
            ++++V  R++ F     + E+E  Q  +K++KSLKN V+PD++ + YGADTLRVYEM MG
Sbjct  584  ATDKVEKRDGSFFHVETGEELE--QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMG  641

Query  771  PLEASRPWATKDVVGAYRFLQRVWRLVVDEHTGETRVADGVELDIDTLRALHRTIVGVSE  830
            PL+AS +W+  ++ G+ +FL+RV RL+   +  E    ++  LD    +  + T+ +V+E
Sbjct  642  PLDASIAWSEEGLEGSRKFLDRVYRLITTKEITE---ENSGALD----KVYNETVKAVTE  694

Query  831  DFAALRNNTATAKLIEYTNHLTKKHRDAVPRAAVEPLVQMLAPLAPHIAEELWLRLGNTT  890
            +   ++ NTA A+L+ + N   K ++  +       +VQ++AP+APH++EELW  L  + 
Sbjct  695  QVDQMKFNTAIAQLMVFVNAANKEDK--LFSDYAKGFVQLIAPFAPHLGEELWQALTASG  752

Query  891  -SLAHGPFPKADAAYLVDETVEYPVQVNGKVRGRVVVAADTDEETLKAAVLTDEKVQAFL  949
             S++  P P  D + LV++ VE  VQ++GKV++++VVA D   E L+   L++EKVQA +
Sbjct  753  ESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEI  812

Query  950  AGATPRKVIVVAGRLVNLVI  969
            AG    KVI V+ +LVN+VI
Sbjct  813  AGKDIIKVIAVPNKLVNIVI  832


 Score =  129 bits (474),  Expect = 7e-31, Method: Compositional matrix adjust.
 Identities = 73/148 (50%), Positives = 99/148 (67%), Gaps = 11/148 (7%)

Query  35   LERTWQENWARLGTFNVPNPVGSLAPPDGAAVPDDKLFVQDMFPYPSGEGLHVGHPLGYI  94
            +E  WQ  WA   TF+            G+  +  K++  DMFPYPSG GLHVGHP GY 
Sbjct  9    IEPKWQAFWADNHTFKT-----------GTDASKPKFYALDMFPYPSGAGLHVGHPEGYT  57

Query  95   ATDVYARYFRMVGRNVLHALGFDAFGLPAEQYAVQTGTHPRTRTEANVVNFRRQLGRLGF  154
            ATD+ +R+ R  G+NVLH++G DAFGLPAEQYA++TG +P   T  N+ NF+RQ+  LGF
Sbjct  58   ATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGF  117

Query  155  GHDSRRSFSTTDVDFYRWTQWIFLQIYN  182
            + D  R  +TTD ++Y+WTQWIF ++Y+
Sbjct  118  SYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1534) leuS in NC_017524


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  510 bits (1924),  Expect = 2e-145, Method: Compositional matrix adjust.
 Identities = 349/740 (48%), Positives = 501/740 (68%), Gaps = 57/740 (7%)

Query  232  LVYRADSLVNWCPGLGTVLANEEVTADGRSDRGNFPVFRKRLRQWMMRITAYAdrllddl  291
            L Y A+  VNW   LGT +ANEEV +DG S+RG +PV RK +RQWM++ITAYA+RLL+DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  292  dvldWPEQVKTMQRNWIGRSTGAVALFSARAASDDGFEVDIEVFTTRPDTLFGATYLVLA  351
            + +DWPE +K MQRNWIG+STGA   F  + +     + D+ VFTTRPDTLFGATY VLA
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDT-----DKDFTVFTTRPDTLFGATYAVLA  262

Query  352  PEHDLVDELVAASWPAGVNPLWTYGGGTPGEaiaayrraiaaKSDLERQE-SREKTGVFL  410
            PEH LVD + ++                 +EA+A Y+R  + KSDL R + ++EKTGV  
Sbjct  263  PEHALVDAITTSD---------------QAEAVADYKRQASLKSDLARTDLAKEKTGVWT  307

Query  411  GSYAINPANGEPVPIFIADYVLAGYGTGAIMAVPGHDQRDWDFARAFGLPIVEVIAGGNI  470
            GSYAINP NG  +P+ IADYVLA+YGTGAIMAVP+HD+RDW+FA+ F L I+ V+ GGN+
Sbjct  308  GSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNV  367

Query  471  SESAYTGDGILVNSDYLNGMSVPAAKRAIVDRLESAGRGRARIEFKLRDWLFARQRYWGE  530
             E+A+T DG+ +NSD+L+G+  ++A   +V++LE+ G G   + ++LRDWLF+RQRYWGE
Sbjct  368  EEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGE  427

Query  531  PFPIVYDSDGRPHALDEAALPVELPDVPDYSPVLFdpddadsepsppLAKATEWVHVDLD  590
            P+PI+   DG + A+ E+ LP+ LP   D  P         +   +PLA+ T+W++V  +
Sbjct  428  PIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTDWLEVTRE  479

Query  591  LGDGLKPYSRDTNVMPQWAGSSWYELRYTDPHNSERFCAKENEAYWMGPRPAEHGPDDPG  650
              DG+K   R+TN MPQWAGSSWY LRY DPHN+E++   E    W+             
Sbjct  480  --DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWL-------------  523

Query  651  GVDLYVGGAEHAVLHLLYSRFWHKVLYDLGHVSSREPYRRLVNQGYIQAYAYTDARGSYV  710
             VD+YVGGAEHAVLHLLY+RFWHKVLYDLG V+++EP+++L NQG I + +Y D+RG+ V
Sbjct  524  PVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALV  583

Query  711  PAEQVIERGDRFVYPGPDGEVEVFQEFGKIGKSLKNSVSPDEICDAYGADTLRVYEMSMG  770
            ++++V  R++ F     + E+E  Q  +K++KSLKN V+PD++ + YGADTLRVYEM MG
Sbjct  584  ATDKVEKRDGSFFHVETGEELE--QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMG  641

Query  771  PLEASRPWATKDVVGAYRFLQRVWRLVVDEHTGETRVADGVELDIDTLRALHRTIVGVSE  830
            PL+AS +W+  ++ G+ +FL+RV RL+   +  E    ++  LD    +  + T+ +V+E
Sbjct  642  PLDASIAWSEEGLEGSRKFLDRVYRLITTKEITE---ENSGALD----KVYNETVKAVTE  694

Query  831  DFAALRNNTATAKLIEYTNHLTKKHRDAVPRAAVEPLVQMLAPLAPHIAEELWLRLGNTT  890
            +   ++ NTA A+L+ + N   K ++  +       +VQ++AP+APH++EELW  L  + 
Sbjct  695  QVDQMKFNTAIAQLMVFVNAANKEDK--LFSDYAKGFVQLIAPFAPHLGEELWQALTASG  752

Query  891  -SLAHGPFPKADAAYLVDETVEYPVQVNGKVRGRVVVAADTDEETLKAAVLTDEKVQAFL  949
             S++  P P  D + LV++ VE  VQ++GKV++++VVA D   E L+   L++EKVQA +
Sbjct  753  ESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEI  812

Query  950  AGATPRKVIVVAGRLVNLVI  969
            AG    KVI V+ +LVN+VI
Sbjct  813  AGKDIIKVIAVPNKLVNIVI  832


 Score =  129 bits (474),  Expect = 7e-31, Method: Compositional matrix adjust.
 Identities = 73/148 (50%), Positives = 99/148 (67%), Gaps = 11/148 (7%)

Query  35   LERTWQENWARLGTFNVPNPVGSLAPPDGAAVPDDKLFVQDMFPYPSGEGLHVGHPLGYI  94
            +E  WQ  WA   TF+            G+  +  K++  DMFPYPSG GLHVGHP GY 
Sbjct  9    IEPKWQAFWADNHTFKT-----------GTDASKPKFYALDMFPYPSGAGLHVGHPEGYT  57

Query  95   ATDVYARYFRMVGRNVLHALGFDAFGLPAEQYAVQTGTHPRTRTEANVVNFRRQLGRLGF  154
            ATD+ +R+ R  G+NVLH++G DAFGLPAEQYA++TG +P   T  N+ NF+RQ+  LGF
Sbjct  58   ATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGF  117

Query  155  GHDSRRSFSTTDVDFYRWTQWIFLQIYN  182
            + D  R  +TTD ++Y+WTQWIF ++Y+
Sbjct  118  SYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1535) leuS in NC_021194


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  510 bits (1924),  Expect = 2e-145, Method: Compositional matrix adjust.
 Identities = 349/740 (48%), Positives = 501/740 (68%), Gaps = 57/740 (7%)

Query  232  LVYRADSLVNWCPGLGTVLANEEVTADGRSDRGNFPVFRKRLRQWMMRITAYAdrllddl  291
            L Y A+  VNW   LGT +ANEEV +DG S+RG +PV RK +RQWM++ITAYA+RLL+DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  292  dvldWPEQVKTMQRNWIGRSTGAVALFSARAASDDGFEVDIEVFTTRPDTLFGATYLVLA  351
            + +DWPE +K MQRNWIG+STGA   F  + +     + D+ VFTTRPDTLFGATY VLA
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDT-----DKDFTVFTTRPDTLFGATYAVLA  262

Query  352  PEHDLVDELVAASWPAGVNPLWTYGGGTPGEaiaayrraiaaKSDLERQE-SREKTGVFL  410
            PEH LVD + ++                 +EA+A Y+R  + KSDL R + ++EKTGV  
Sbjct  263  PEHALVDAITTSD---------------QAEAVADYKRQASLKSDLARTDLAKEKTGVWT  307

Query  411  GSYAINPANGEPVPIFIADYVLAGYGTGAIMAVPGHDQRDWDFARAFGLPIVEVIAGGNI  470
            GSYAINP NG  +P+ IADYVLA+YGTGAIMAVP+HD+RDW+FA+ F L I+ V+ GGN+
Sbjct  308  GSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNV  367

Query  471  SESAYTGDGILVNSDYLNGMSVPAAKRAIVDRLESAGRGRARIEFKLRDWLFARQRYWGE  530
             E+A+T DG+ +NSD+L+G+  ++A   +V++LE+ G G   + ++LRDWLF+RQRYWGE
Sbjct  368  EEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGE  427

Query  531  PFPIVYDSDGRPHALDEAALPVELPDVPDYSPVLFdpddadsepsppLAKATEWVHVDLD  590
            P+PI+   DG + A+ E+ LP+ LP   D  P         +   +PLA+ T+W++V  +
Sbjct  428  PIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTDWLEVTRE  479

Query  591  LGDGLKPYSRDTNVMPQWAGSSWYELRYTDPHNSERFCAKENEAYWMGPRPAEHGPDDPG  650
              DG+K   R+TN MPQWAGSSWY LRY DPHN+E++   E    W+             
Sbjct  480  --DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWL-------------  523

Query  651  GVDLYVGGAEHAVLHLLYSRFWHKVLYDLGHVSSREPYRRLVNQGYIQAYAYTDARGSYV  710
             VD+YVGGAEHAVLHLLY+RFWHKVLYDLG V+++EP+++L NQG I + +Y D+RG+ V
Sbjct  524  PVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALV  583

Query  711  PAEQVIERGDRFVYPGPDGEVEVFQEFGKIGKSLKNSVSPDEICDAYGADTLRVYEMSMG  770
            ++++V  R++ F     + E+E  Q  +K++KSLKN V+PD++ + YGADTLRVYEM MG
Sbjct  584  ATDKVEKRDGSFFHVETGEELE--QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMG  641

Query  771  PLEASRPWATKDVVGAYRFLQRVWRLVVDEHTGETRVADGVELDIDTLRALHRTIVGVSE  830
            PL+AS +W+  ++ G+ +FL+RV RL+   +  E    ++  LD    +  + T+ +V+E
Sbjct  642  PLDASIAWSEEGLEGSRKFLDRVYRLITTKEITE---ENSGALD----KVYNETVKAVTE  694

Query  831  DFAALRNNTATAKLIEYTNHLTKKHRDAVPRAAVEPLVQMLAPLAPHIAEELWLRLGNTT  890
            +   ++ NTA A+L+ + N   K ++  +       +VQ++AP+APH++EELW  L  + 
Sbjct  695  QVDQMKFNTAIAQLMVFVNAANKEDK--LFSDYAKGFVQLIAPFAPHLGEELWQALTASG  752

Query  891  -SLAHGPFPKADAAYLVDETVEYPVQVNGKVRGRVVVAADTDEETLKAAVLTDEKVQAFL  949
             S++  P P  D + LV++ VE  VQ++GKV++++VVA D   E L+   L++EKVQA +
Sbjct  753  ESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEI  812

Query  950  AGATPRKVIVVAGRLVNLVI  969
            AG    KVI V+ +LVN+VI
Sbjct  813  AGKDIIKVIAVPNKLVNIVI  832


 Score =  129 bits (474),  Expect = 7e-31, Method: Compositional matrix adjust.
 Identities = 73/148 (50%), Positives = 99/148 (67%), Gaps = 11/148 (7%)

Query  35   LERTWQENWARLGTFNVPNPVGSLAPPDGAAVPDDKLFVQDMFPYPSGEGLHVGHPLGYI  94
            +E  WQ  WA   TF+            G+  +  K++  DMFPYPSG GLHVGHP GY 
Sbjct  9    IEPKWQAFWADNHTFKT-----------GTDASKPKFYALDMFPYPSGAGLHVGHPEGYT  57

Query  95   ATDVYARYFRMVGRNVLHALGFDAFGLPAEQYAVQTGTHPRTRTEANVVNFRRQLGRLGF  154
            ATD+ +R+ R  G+NVLH++G DAFGLPAEQYA++TG +P   T  N+ NF+RQ+  LGF
Sbjct  58   ATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGF  117

Query  155  GHDSRRSFSTTDVDFYRWTQWIFLQIYN  182
            + D  R  +TTD ++Y+WTQWIF ++Y+
Sbjct  118  SYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1536) M943_00240 in NC_021740


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  510 bits (1924),  Expect = 2e-145, Method: Compositional matrix adjust.
 Identities = 349/740 (48%), Positives = 501/740 (68%), Gaps = 57/740 (7%)

Query  232  LVYRADSLVNWCPGLGTVLANEEVTADGRSDRGNFPVFRKRLRQWMMRITAYAdrllddl  291
            L Y A+  VNW   LGT +ANEEV +DG S+RG +PV RK +RQWM++ITAYA+RLL+DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  292  dvldWPEQVKTMQRNWIGRSTGAVALFSARAASDDGFEVDIEVFTTRPDTLFGATYLVLA  351
            + +DWPE +K MQRNWIG+STGA   F  + +     + D+ VFTTRPDTLFGATY VLA
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDT-----DKDFTVFTTRPDTLFGATYAVLA  262

Query  352  PEHDLVDELVAASWPAGVNPLWTYGGGTPGEaiaayrraiaaKSDLERQE-SREKTGVFL  410
            PEH LVD + ++                 +EA+A Y+R  + KSDL R + ++EKTGV  
Sbjct  263  PEHALVDAITTSD---------------QAEAVADYKRQASLKSDLARTDLAKEKTGVWT  307

Query  411  GSYAINPANGEPVPIFIADYVLAGYGTGAIMAVPGHDQRDWDFARAFGLPIVEVIAGGNI  470
            GSYAINP NG  +P+ IADYVLA+YGTGAIMAVP+HD+RDW+FA+ F L I+ V+ GGN+
Sbjct  308  GSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNV  367

Query  471  SESAYTGDGILVNSDYLNGMSVPAAKRAIVDRLESAGRGRARIEFKLRDWLFARQRYWGE  530
             E+A+T DG+ +NSD+L+G+  ++A   +V++LE+ G G   + ++LRDWLF+RQRYWGE
Sbjct  368  EEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGE  427

Query  531  PFPIVYDSDGRPHALDEAALPVELPDVPDYSPVLFdpddadsepsppLAKATEWVHVDLD  590
            P+PI+   DG + A+ E+ LP+ LP   D  P         +   +PLA+ T+W++V  +
Sbjct  428  PIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTDWLEVTRE  479

Query  591  LGDGLKPYSRDTNVMPQWAGSSWYELRYTDPHNSERFCAKENEAYWMGPRPAEHGPDDPG  650
              DG+K   R+TN MPQWAGSSWY LRY DPHN+E++   E    W+             
Sbjct  480  --DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWL-------------  523

Query  651  GVDLYVGGAEHAVLHLLYSRFWHKVLYDLGHVSSREPYRRLVNQGYIQAYAYTDARGSYV  710
             VD+YVGGAEHAVLHLLY+RFWHKVLYDLG V+++EP+++L NQG I + +Y D+RG+ V
Sbjct  524  PVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALV  583

Query  711  PAEQVIERGDRFVYPGPDGEVEVFQEFGKIGKSLKNSVSPDEICDAYGADTLRVYEMSMG  770
            ++++V  R++ F     + E+E  Q  +K++KSLKN V+PD++ + YGADTLRVYEM MG
Sbjct  584  ATDKVEKRDGSFFHVETGEELE--QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMG  641

Query  771  PLEASRPWATKDVVGAYRFLQRVWRLVVDEHTGETRVADGVELDIDTLRALHRTIVGVSE  830
            PL+AS +W+  ++ G+ +FL+RV RL+   +  E    ++  LD    +  + T+ +V+E
Sbjct  642  PLDASIAWSEEGLEGSRKFLDRVYRLITTKEITE---ENSGALD----KVYNETVKAVTE  694

Query  831  DFAALRNNTATAKLIEYTNHLTKKHRDAVPRAAVEPLVQMLAPLAPHIAEELWLRLGNTT  890
            +   ++ NTA A+L+ + N   K ++  +       +VQ++AP+APH++EELW  L  + 
Sbjct  695  QVDQMKFNTAIAQLMVFVNAANKEDK--LFSDYAKGFVQLIAPFAPHLGEELWQALTASG  752

Query  891  -SLAHGPFPKADAAYLVDETVEYPVQVNGKVRGRVVVAADTDEETLKAAVLTDEKVQAFL  949
             S++  P P  D + LV++ VE  VQ++GKV++++VVA D   E L+   L++EKVQA +
Sbjct  753  ESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEI  812

Query  950  AGATPRKVIVVAGRLVNLVI  969
            AG    KVI V+ +LVN+VI
Sbjct  813  AGKDIIKVIAVPNKLVNIVI  832


 Score =  129 bits (474),  Expect = 7e-31, Method: Compositional matrix adjust.
 Identities = 73/148 (50%), Positives = 99/148 (67%), Gaps = 11/148 (7%)

Query  35   LERTWQENWARLGTFNVPNPVGSLAPPDGAAVPDDKLFVQDMFPYPSGEGLHVGHPLGYI  94
            +E  WQ  WA   TF+            G+  +  K++  DMFPYPSG GLHVGHP GY 
Sbjct  9    IEPKWQAFWADNHTFKT-----------GTDASKPKFYALDMFPYPSGAGLHVGHPEGYT  57

Query  95   ATDVYARYFRMVGRNVLHALGFDAFGLPAEQYAVQTGTHPRTRTEANVVNFRRQLGRLGF  154
            ATD+ +R+ R  G+NVLH++G DAFGLPAEQYA++TG +P   T  N+ NF+RQ+  LGF
Sbjct  58   ATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGF  117

Query  155  GHDSRRSFSTTDVDFYRWTQWIFLQIYN  182
            + D  R  +TTD ++Y+WTQWIF ++Y+
Sbjct  118  SYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1537) leuS in NC_020559


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  510 bits (1924),  Expect = 2e-145, Method: Compositional matrix adjust.
 Identities = 349/740 (48%), Positives = 501/740 (68%), Gaps = 57/740 (7%)

Query  232  LVYRADSLVNWCPGLGTVLANEEVTADGRSDRGNFPVFRKRLRQWMMRITAYAdrllddl  291
            L Y A+  VNW   LGT +ANEEV +DG S+RG +PV RK +RQWM++ITAYA+RLL+DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  292  dvldWPEQVKTMQRNWIGRSTGAVALFSARAASDDGFEVDIEVFTTRPDTLFGATYLVLA  351
            + +DWPE +K MQRNWIG+STGA   F  + +     + D+ VFTTRPDTLFGATY VLA
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDT-----DKDFTVFTTRPDTLFGATYAVLA  262

Query  352  PEHDLVDELVAASWPAGVNPLWTYGGGTPGEaiaayrraiaaKSDLERQE-SREKTGVFL  410
            PEH LVD + ++                 +EA+A Y+R  + KSDL R + ++EKTGV  
Sbjct  263  PEHALVDAITTSD---------------QAEAVADYKRQASLKSDLARTDLAKEKTGVWT  307

Query  411  GSYAINPANGEPVPIFIADYVLAGYGTGAIMAVPGHDQRDWDFARAFGLPIVEVIAGGNI  470
            GSYAINP NG  +P+ IADYVLA+YGTGAIMAVP+HD+RDW+FA+ F L I+ V+ GGN+
Sbjct  308  GSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNV  367

Query  471  SESAYTGDGILVNSDYLNGMSVPAAKRAIVDRLESAGRGRARIEFKLRDWLFARQRYWGE  530
             E+A+T DG+ +NSD+L+G+  ++A   +V++LE+ G G   + ++LRDWLF+RQRYWGE
Sbjct  368  EEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGE  427

Query  531  PFPIVYDSDGRPHALDEAALPVELPDVPDYSPVLFdpddadsepsppLAKATEWVHVDLD  590
            P+PI+   DG + A+ E+ LP+ LP   D  P         +   +PLA+ T+W++V  +
Sbjct  428  PIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTDWLEVTRE  479

Query  591  LGDGLKPYSRDTNVMPQWAGSSWYELRYTDPHNSERFCAKENEAYWMGPRPAEHGPDDPG  650
              DG+K   R+TN MPQWAGSSWY LRY DPHN+E++   E    W+             
Sbjct  480  --DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWL-------------  523

Query  651  GVDLYVGGAEHAVLHLLYSRFWHKVLYDLGHVSSREPYRRLVNQGYIQAYAYTDARGSYV  710
             VD+YVGGAEHAVLHLLY+RFWHKVLYDLG V+++EP+++L NQG I + +Y D+RG+ V
Sbjct  524  PVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALV  583

Query  711  PAEQVIERGDRFVYPGPDGEVEVFQEFGKIGKSLKNSVSPDEICDAYGADTLRVYEMSMG  770
            ++++V  R++ F     + E+E  Q  +K++KSLKN V+PD++ + YGADTLRVYEM MG
Sbjct  584  ATDKVEKRDGSFFHVETGEELE--QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMG  641

Query  771  PLEASRPWATKDVVGAYRFLQRVWRLVVDEHTGETRVADGVELDIDTLRALHRTIVGVSE  830
            PL+AS +W+  ++ G+ +FL+RV RL+   +  E    ++  LD    +  + T+ +V+E
Sbjct  642  PLDASIAWSEEGLEGSRKFLDRVYRLITTKEITE---ENSGALD----KVYNETVKAVTE  694

Query  831  DFAALRNNTATAKLIEYTNHLTKKHRDAVPRAAVEPLVQMLAPLAPHIAEELWLRLGNTT  890
            +   ++ NTA A+L+ + N   K ++  +       +VQ++AP+APH++EELW  L  + 
Sbjct  695  QVDQMKFNTAIAQLMVFVNAANKEDK--LFSDYAKGFVQLIAPFAPHLGEELWQALTASG  752

Query  891  -SLAHGPFPKADAAYLVDETVEYPVQVNGKVRGRVVVAADTDEETLKAAVLTDEKVQAFL  949
             S++  P P  D + LV++ VE  VQ++GKV++++VVA D   E L+   L++EKVQA +
Sbjct  753  ESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEI  812

Query  950  AGATPRKVIVVAGRLVNLVI  969
            AG    KVI V+ +LVN+VI
Sbjct  813  AGKDIIKVIAVPNKLVNIVI  832


 Score =  129 bits (474),  Expect = 7e-31, Method: Compositional matrix adjust.
 Identities = 73/148 (50%), Positives = 99/148 (67%), Gaps = 11/148 (7%)

Query  35   LERTWQENWARLGTFNVPNPVGSLAPPDGAAVPDDKLFVQDMFPYPSGEGLHVGHPLGYI  94
            +E  WQ  WA   TF+            G+  +  K++  DMFPYPSG GLHVGHP GY 
Sbjct  9    IEPKWQAFWADNHTFKT-----------GTDASKPKFYALDMFPYPSGAGLHVGHPEGYT  57

Query  95   ATDVYARYFRMVGRNVLHALGFDAFGLPAEQYAVQTGTHPRTRTEANVVNFRRQLGRLGF  154
            ATD+ +R+ R  G+NVLH++G DAFGLPAEQYA++TG +P   T  N+ NF+RQ+  LGF
Sbjct  58   ATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGF  117

Query  155  GHDSRRSFSTTDVDFYRWTQWIFLQIYN  182
            + D  R  +TTD ++Y+WTQWIF ++Y+
Sbjct  118  SYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1538) leuS in NC_009565


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  510 bits (1924),  Expect = 2e-145, Method: Compositional matrix adjust.
 Identities = 349/740 (48%), Positives = 501/740 (68%), Gaps = 57/740 (7%)

Query  232  LVYRADSLVNWCPGLGTVLANEEVTADGRSDRGNFPVFRKRLRQWMMRITAYAdrllddl  291
            L Y A+  VNW   LGT +ANEEV +DG S+RG +PV RK +RQWM++ITAYA+RLL+DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  292  dvldWPEQVKTMQRNWIGRSTGAVALFSARAASDDGFEVDIEVFTTRPDTLFGATYLVLA  351
            + +DWPE +K MQRNWIG+STGA   F  + +     + D+ VFTTRPDTLFGATY VLA
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDT-----DKDFTVFTTRPDTLFGATYAVLA  262

Query  352  PEHDLVDELVAASWPAGVNPLWTYGGGTPGEaiaayrraiaaKSDLERQE-SREKTGVFL  410
            PEH LVD + ++                 +EA+A Y+R  + KSDL R + ++EKTGV  
Sbjct  263  PEHALVDAITTSD---------------QAEAVADYKRQASLKSDLARTDLAKEKTGVWT  307

Query  411  GSYAINPANGEPVPIFIADYVLAGYGTGAIMAVPGHDQRDWDFARAFGLPIVEVIAGGNI  470
            GSYAINP NG  +P+ IADYVLA+YGTGAIMAVP+HD+RDW+FA+ F L I+ V+ GGN+
Sbjct  308  GSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNV  367

Query  471  SESAYTGDGILVNSDYLNGMSVPAAKRAIVDRLESAGRGRARIEFKLRDWLFARQRYWGE  530
             E+A+T DG+ +NSD+L+G+  ++A   +V++LE+ G G   + ++LRDWLF+RQRYWGE
Sbjct  368  EEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGE  427

Query  531  PFPIVYDSDGRPHALDEAALPVELPDVPDYSPVLFdpddadsepsppLAKATEWVHVDLD  590
            P+PI+   DG + A+ E+ LP+ LP   D  P         +   +PLA+ T+W++V  +
Sbjct  428  PIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTDWLEVTRE  479

Query  591  LGDGLKPYSRDTNVMPQWAGSSWYELRYTDPHNSERFCAKENEAYWMGPRPAEHGPDDPG  650
              DG+K   R+TN MPQWAGSSWY LRY DPHN+E++   E    W+             
Sbjct  480  --DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWL-------------  523

Query  651  GVDLYVGGAEHAVLHLLYSRFWHKVLYDLGHVSSREPYRRLVNQGYIQAYAYTDARGSYV  710
             VD+YVGGAEHAVLHLLY+RFWHKVLYDLG V+++EP+++L NQG I + +Y D+RG+ V
Sbjct  524  PVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALV  583

Query  711  PAEQVIERGDRFVYPGPDGEVEVFQEFGKIGKSLKNSVSPDEICDAYGADTLRVYEMSMG  770
            ++++V  R++ F     + E+E  Q  +K++KSLKN V+PD++ + YGADTLRVYEM MG
Sbjct  584  ATDKVEKRDGSFFHVETGEELE--QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMG  641

Query  771  PLEASRPWATKDVVGAYRFLQRVWRLVVDEHTGETRVADGVELDIDTLRALHRTIVGVSE  830
            PL+AS +W+  ++ G+ +FL+RV RL+   +  E    ++  LD    +  + T+ +V+E
Sbjct  642  PLDASIAWSEEGLEGSRKFLDRVYRLITTKEITE---ENSGALD----KVYNETVKAVTE  694

Query  831  DFAALRNNTATAKLIEYTNHLTKKHRDAVPRAAVEPLVQMLAPLAPHIAEELWLRLGNTT  890
            +   ++ NTA A+L+ + N   K ++  +       +VQ++AP+APH++EELW  L  + 
Sbjct  695  QVDQMKFNTAIAQLMVFVNAANKEDK--LFSDYAKGFVQLIAPFAPHLGEELWQALTASG  752

Query  891  -SLAHGPFPKADAAYLVDETVEYPVQVNGKVRGRVVVAADTDEETLKAAVLTDEKVQAFL  949
             S++  P P  D + LV++ VE  VQ++GKV++++VVA D   E L+   L++EKVQA +
Sbjct  753  ESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEI  812

Query  950  AGATPRKVIVVAGRLVNLVI  969
            AG    KVI V+ +LVN+VI
Sbjct  813  AGKDIIKVIAVPNKLVNIVI  832


 Score =  129 bits (474),  Expect = 7e-31, Method: Compositional matrix adjust.
 Identities = 73/148 (50%), Positives = 99/148 (67%), Gaps = 11/148 (7%)

Query  35   LERTWQENWARLGTFNVPNPVGSLAPPDGAAVPDDKLFVQDMFPYPSGEGLHVGHPLGYI  94
            +E  WQ  WA   TF+            G+  +  K++  DMFPYPSG GLHVGHP GY 
Sbjct  9    IEPKWQAFWADNHTFKT-----------GTDASKPKFYALDMFPYPSGAGLHVGHPEGYT  57

Query  95   ATDVYARYFRMVGRNVLHALGFDAFGLPAEQYAVQTGTHPRTRTEANVVNFRRQLGRLGF  154
            ATD+ +R+ R  G+NVLH++G DAFGLPAEQYA++TG +P   T  N+ NF+RQ+  LGF
Sbjct  58   ATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGF  117

Query  155  GHDSRRSFSTTDVDFYRWTQWIFLQIYN  182
            + D  R  +TTD ++Y+WTQWIF ++Y+
Sbjct  118  SYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1539) leuS in NC_009525


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  510 bits (1924),  Expect = 2e-145, Method: Compositional matrix adjust.
 Identities = 349/740 (48%), Positives = 501/740 (68%), Gaps = 57/740 (7%)

Query  232  LVYRADSLVNWCPGLGTVLANEEVTADGRSDRGNFPVFRKRLRQWMMRITAYAdrllddl  291
            L Y A+  VNW   LGT +ANEEV +DG S+RG +PV RK +RQWM++ITAYA+RLL+DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  292  dvldWPEQVKTMQRNWIGRSTGAVALFSARAASDDGFEVDIEVFTTRPDTLFGATYLVLA  351
            + +DWPE +K MQRNWIG+STGA   F  + +     + D+ VFTTRPDTLFGATY VLA
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDT-----DKDFTVFTTRPDTLFGATYAVLA  262

Query  352  PEHDLVDELVAASWPAGVNPLWTYGGGTPGEaiaayrraiaaKSDLERQE-SREKTGVFL  410
            PEH LVD + ++                 +EA+A Y+R  + KSDL R + ++EKTGV  
Sbjct  263  PEHALVDAITTSD---------------QAEAVADYKRQASLKSDLARTDLAKEKTGVWT  307

Query  411  GSYAINPANGEPVPIFIADYVLAGYGTGAIMAVPGHDQRDWDFARAFGLPIVEVIAGGNI  470
            GSYAINP NG  +P+ IADYVLA+YGTGAIMAVP+HD+RDW+FA+ F L I+ V+ GGN+
Sbjct  308  GSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNV  367

Query  471  SESAYTGDGILVNSDYLNGMSVPAAKRAIVDRLESAGRGRARIEFKLRDWLFARQRYWGE  530
             E+A+T DG+ +NSD+L+G+  ++A   +V++LE+ G G   + ++LRDWLF+RQRYWGE
Sbjct  368  EEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGE  427

Query  531  PFPIVYDSDGRPHALDEAALPVELPDVPDYSPVLFdpddadsepsppLAKATEWVHVDLD  590
            P+PI+   DG + A+ E+ LP+ LP   D  P         +   +PLA+ T+W++V  +
Sbjct  428  PIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTDWLEVTRE  479

Query  591  LGDGLKPYSRDTNVMPQWAGSSWYELRYTDPHNSERFCAKENEAYWMGPRPAEHGPDDPG  650
              DG+K   R+TN MPQWAGSSWY LRY DPHN+E++   E    W+             
Sbjct  480  --DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWL-------------  523

Query  651  GVDLYVGGAEHAVLHLLYSRFWHKVLYDLGHVSSREPYRRLVNQGYIQAYAYTDARGSYV  710
             VD+YVGGAEHAVLHLLY+RFWHKVLYDLG V+++EP+++L NQG I + +Y D+RG+ V
Sbjct  524  PVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALV  583

Query  711  PAEQVIERGDRFVYPGPDGEVEVFQEFGKIGKSLKNSVSPDEICDAYGADTLRVYEMSMG  770
            ++++V  R++ F     + E+E  Q  +K++KSLKN V+PD++ + YGADTLRVYEM MG
Sbjct  584  ATDKVEKRDGSFFHVETGEELE--QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMG  641

Query  771  PLEASRPWATKDVVGAYRFLQRVWRLVVDEHTGETRVADGVELDIDTLRALHRTIVGVSE  830
            PL+AS +W+  ++ G+ +FL+RV RL+   +  E    ++  LD    +  + T+ +V+E
Sbjct  642  PLDASIAWSEEGLEGSRKFLDRVYRLITTKEITE---ENSGALD----KVYNETVKAVTE  694

Query  831  DFAALRNNTATAKLIEYTNHLTKKHRDAVPRAAVEPLVQMLAPLAPHIAEELWLRLGNTT  890
            +   ++ NTA A+L+ + N   K ++  +       +VQ++AP+APH++EELW  L  + 
Sbjct  695  QVDQMKFNTAIAQLMVFVNAANKEDK--LFSDYAKGFVQLIAPFAPHLGEELWQALTASG  752

Query  891  -SLAHGPFPKADAAYLVDETVEYPVQVNGKVRGRVVVAADTDEETLKAAVLTDEKVQAFL  949
             S++  P P  D + LV++ VE  VQ++GKV++++VVA D   E L+   L++EKVQA +
Sbjct  753  ESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEI  812

Query  950  AGATPRKVIVVAGRLVNLVI  969
            AG    KVI V+ +LVN+VI
Sbjct  813  AGKDIIKVIAVPNKLVNIVI  832


 Score =  129 bits (474),  Expect = 7e-31, Method: Compositional matrix adjust.
 Identities = 73/148 (50%), Positives = 99/148 (67%), Gaps = 11/148 (7%)

Query  35   LERTWQENWARLGTFNVPNPVGSLAPPDGAAVPDDKLFVQDMFPYPSGEGLHVGHPLGYI  94
            +E  WQ  WA   TF+            G+  +  K++  DMFPYPSG GLHVGHP GY 
Sbjct  9    IEPKWQAFWADNHTFKT-----------GTDASKPKFYALDMFPYPSGAGLHVGHPEGYT  57

Query  95   ATDVYARYFRMVGRNVLHALGFDAFGLPAEQYAVQTGTHPRTRTEANVVNFRRQLGRLGF  154
            ATD+ +R+ R  G+NVLH++G DAFGLPAEQYA++TG +P   T  N+ NF+RQ+  LGF
Sbjct  58   ATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGF  117

Query  155  GHDSRRSFSTTDVDFYRWTQWIFLQIYN  182
            + D  R  +TTD ++Y+WTQWIF ++Y+
Sbjct  118  SYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1540) RVBD_0041 in NC_018143


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  510 bits (1924),  Expect = 2e-145, Method: Compositional matrix adjust.
 Identities = 349/740 (48%), Positives = 501/740 (68%), Gaps = 57/740 (7%)

Query  232  LVYRADSLVNWCPGLGTVLANEEVTADGRSDRGNFPVFRKRLRQWMMRITAYAdrllddl  291
            L Y A+  VNW   LGT +ANEEV +DG S+RG +PV RK +RQWM++ITAYA+RLL+DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  292  dvldWPEQVKTMQRNWIGRSTGAVALFSARAASDDGFEVDIEVFTTRPDTLFGATYLVLA  351
            + +DWPE +K MQRNWIG+STGA   F  + +     + D+ VFTTRPDTLFGATY VLA
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDT-----DKDFTVFTTRPDTLFGATYAVLA  262

Query  352  PEHDLVDELVAASWPAGVNPLWTYGGGTPGEaiaayrraiaaKSDLERQE-SREKTGVFL  410
            PEH LVD + ++                 +EA+A Y+R  + KSDL R + ++EKTGV  
Sbjct  263  PEHALVDAITTSD---------------QAEAVADYKRQASLKSDLARTDLAKEKTGVWT  307

Query  411  GSYAINPANGEPVPIFIADYVLAGYGTGAIMAVPGHDQRDWDFARAFGLPIVEVIAGGNI  470
            GSYAINP NG  +P+ IADYVLA+YGTGAIMAVP+HD+RDW+FA+ F L I+ V+ GGN+
Sbjct  308  GSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNV  367

Query  471  SESAYTGDGILVNSDYLNGMSVPAAKRAIVDRLESAGRGRARIEFKLRDWLFARQRYWGE  530
             E+A+T DG+ +NSD+L+G+  ++A   +V++LE+ G G   + ++LRDWLF+RQRYWGE
Sbjct  368  EEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGE  427

Query  531  PFPIVYDSDGRPHALDEAALPVELPDVPDYSPVLFdpddadsepsppLAKATEWVHVDLD  590
            P+PI+   DG + A+ E+ LP+ LP   D  P         +   +PLA+ T+W++V  +
Sbjct  428  PIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTDWLEVTRE  479

Query  591  LGDGLKPYSRDTNVMPQWAGSSWYELRYTDPHNSERFCAKENEAYWMGPRPAEHGPDDPG  650
              DG+K   R+TN MPQWAGSSWY LRY DPHN+E++   E    W+             
Sbjct  480  --DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWL-------------  523

Query  651  GVDLYVGGAEHAVLHLLYSRFWHKVLYDLGHVSSREPYRRLVNQGYIQAYAYTDARGSYV  710
             VD+YVGGAEHAVLHLLY+RFWHKVLYDLG V+++EP+++L NQG I + +Y D+RG+ V
Sbjct  524  PVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALV  583

Query  711  PAEQVIERGDRFVYPGPDGEVEVFQEFGKIGKSLKNSVSPDEICDAYGADTLRVYEMSMG  770
            ++++V  R++ F     + E+E  Q  +K++KSLKN V+PD++ + YGADTLRVYEM MG
Sbjct  584  ATDKVEKRDGSFFHVETGEELE--QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMG  641

Query  771  PLEASRPWATKDVVGAYRFLQRVWRLVVDEHTGETRVADGVELDIDTLRALHRTIVGVSE  830
            PL+AS +W+  ++ G+ +FL+RV RL+   +  E    ++  LD    +  + T+ +V+E
Sbjct  642  PLDASIAWSEEGLEGSRKFLDRVYRLITTKEITE---ENSGALD----KVYNETVKAVTE  694

Query  831  DFAALRNNTATAKLIEYTNHLTKKHRDAVPRAAVEPLVQMLAPLAPHIAEELWLRLGNTT  890
            +   ++ NTA A+L+ + N   K ++  +       +VQ++AP+APH++EELW  L  + 
Sbjct  695  QVDQMKFNTAIAQLMVFVNAANKEDK--LFSDYAKGFVQLIAPFAPHLGEELWQALTASG  752

Query  891  -SLAHGPFPKADAAYLVDETVEYPVQVNGKVRGRVVVAADTDEETLKAAVLTDEKVQAFL  949
             S++  P P  D + LV++ VE  VQ++GKV++++VVA D   E L+   L++EKVQA +
Sbjct  753  ESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEI  812

Query  950  AGATPRKVIVVAGRLVNLVI  969
            AG    KVI V+ +LVN+VI
Sbjct  813  AGKDIIKVIAVPNKLVNIVI  832


 Score =  129 bits (474),  Expect = 7e-31, Method: Compositional matrix adjust.
 Identities = 73/148 (50%), Positives = 99/148 (67%), Gaps = 11/148 (7%)

Query  35   LERTWQENWARLGTFNVPNPVGSLAPPDGAAVPDDKLFVQDMFPYPSGEGLHVGHPLGYI  94
            +E  WQ  WA   TF+            G+  +  K++  DMFPYPSG GLHVGHP GY 
Sbjct  9    IEPKWQAFWADNHTFKT-----------GTDASKPKFYALDMFPYPSGAGLHVGHPEGYT  57

Query  95   ATDVYARYFRMVGRNVLHALGFDAFGLPAEQYAVQTGTHPRTRTEANVVNFRRQLGRLGF  154
            ATD+ +R+ R  G+NVLH++G DAFGLPAEQYA++TG +P   T  N+ NF+RQ+  LGF
Sbjct  58   ATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGF  117

Query  155  GHDSRRSFSTTDVDFYRWTQWIFLQIYN  182
            + D  R  +TTD ++Y+WTQWIF ++Y+
Sbjct  118  SYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1541) leuS in NC_000962


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  510 bits (1924),  Expect = 2e-145, Method: Compositional matrix adjust.
 Identities = 349/740 (48%), Positives = 501/740 (68%), Gaps = 57/740 (7%)

Query  232  LVYRADSLVNWCPGLGTVLANEEVTADGRSDRGNFPVFRKRLRQWMMRITAYAdrllddl  291
            L Y A+  VNW   LGT +ANEEV +DG S+RG +PV RK +RQWM++ITAYA+RLL+DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  292  dvldWPEQVKTMQRNWIGRSTGAVALFSARAASDDGFEVDIEVFTTRPDTLFGATYLVLA  351
            + +DWPE +K MQRNWIG+STGA   F  + +     + D+ VFTTRPDTLFGATY VLA
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDT-----DKDFTVFTTRPDTLFGATYAVLA  262

Query  352  PEHDLVDELVAASWPAGVNPLWTYGGGTPGEaiaayrraiaaKSDLERQE-SREKTGVFL  410
            PEH LVD + ++                 +EA+A Y+R  + KSDL R + ++EKTGV  
Sbjct  263  PEHALVDAITTSD---------------QAEAVADYKRQASLKSDLARTDLAKEKTGVWT  307

Query  411  GSYAINPANGEPVPIFIADYVLAGYGTGAIMAVPGHDQRDWDFARAFGLPIVEVIAGGNI  470
            GSYAINP NG  +P+ IADYVLA+YGTGAIMAVP+HD+RDW+FA+ F L I+ V+ GGN+
Sbjct  308  GSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNV  367

Query  471  SESAYTGDGILVNSDYLNGMSVPAAKRAIVDRLESAGRGRARIEFKLRDWLFARQRYWGE  530
             E+A+T DG+ +NSD+L+G+  ++A   +V++LE+ G G   + ++LRDWLF+RQRYWGE
Sbjct  368  EEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGE  427

Query  531  PFPIVYDSDGRPHALDEAALPVELPDVPDYSPVLFdpddadsepsppLAKATEWVHVDLD  590
            P+PI+   DG + A+ E+ LP+ LP   D  P         +   +PLA+ T+W++V  +
Sbjct  428  PIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTDWLEVTRE  479

Query  591  LGDGLKPYSRDTNVMPQWAGSSWYELRYTDPHNSERFCAKENEAYWMGPRPAEHGPDDPG  650
              DG+K   R+TN MPQWAGSSWY LRY DPHN+E++   E    W+             
Sbjct  480  --DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWL-------------  523

Query  651  GVDLYVGGAEHAVLHLLYSRFWHKVLYDLGHVSSREPYRRLVNQGYIQAYAYTDARGSYV  710
             VD+YVGGAEHAVLHLLY+RFWHKVLYDLG V+++EP+++L NQG I + +Y D+RG+ V
Sbjct  524  PVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALV  583

Query  711  PAEQVIERGDRFVYPGPDGEVEVFQEFGKIGKSLKNSVSPDEICDAYGADTLRVYEMSMG  770
            ++++V  R++ F     + E+E  Q  +K++KSLKN V+PD++ + YGADTLRVYEM MG
Sbjct  584  ATDKVEKRDGSFFHVETGEELE--QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMG  641

Query  771  PLEASRPWATKDVVGAYRFLQRVWRLVVDEHTGETRVADGVELDIDTLRALHRTIVGVSE  830
            PL+AS +W+  ++ G+ +FL+RV RL+   +  E    ++  LD    +  + T+ +V+E
Sbjct  642  PLDASIAWSEEGLEGSRKFLDRVYRLITTKEITE---ENSGALD----KVYNETVKAVTE  694

Query  831  DFAALRNNTATAKLIEYTNHLTKKHRDAVPRAAVEPLVQMLAPLAPHIAEELWLRLGNTT  890
            +   ++ NTA A+L+ + N   K ++  +       +VQ++AP+APH++EELW  L  + 
Sbjct  695  QVDQMKFNTAIAQLMVFVNAANKEDK--LFSDYAKGFVQLIAPFAPHLGEELWQALTASG  752

Query  891  -SLAHGPFPKADAAYLVDETVEYPVQVNGKVRGRVVVAADTDEETLKAAVLTDEKVQAFL  949
             S++  P P  D + LV++ VE  VQ++GKV++++VVA D   E L+   L++EKVQA +
Sbjct  753  ESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEI  812

Query  950  AGATPRKVIVVAGRLVNLVI  969
            AG    KVI V+ +LVN+VI
Sbjct  813  AGKDIIKVIAVPNKLVNIVI  832


 Score =  129 bits (474),  Expect = 7e-31, Method: Compositional matrix adjust.
 Identities = 73/148 (50%), Positives = 99/148 (67%), Gaps = 11/148 (7%)

Query  35   LERTWQENWARLGTFNVPNPVGSLAPPDGAAVPDDKLFVQDMFPYPSGEGLHVGHPLGYI  94
            +E  WQ  WA   TF+            G+  +  K++  DMFPYPSG GLHVGHP GY 
Sbjct  9    IEPKWQAFWADNHTFKT-----------GTDASKPKFYALDMFPYPSGAGLHVGHPEGYT  57

Query  95   ATDVYARYFRMVGRNVLHALGFDAFGLPAEQYAVQTGTHPRTRTEANVVNFRRQLGRLGF  154
            ATD+ +R+ R  G+NVLH++G DAFGLPAEQYA++TG +P   T  N+ NF+RQ+  LGF
Sbjct  58   ATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGF  117

Query  155  GHDSRRSFSTTDVDFYRWTQWIFLQIYN  182
            + D  R  +TTD ++Y+WTQWIF ++Y+
Sbjct  118  SYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1542) TBHG_00041 in NC_022350


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  510 bits (1924),  Expect = 2e-145, Method: Compositional matrix adjust.
 Identities = 349/740 (48%), Positives = 501/740 (68%), Gaps = 57/740 (7%)

Query  232  LVYRADSLVNWCPGLGTVLANEEVTADGRSDRGNFPVFRKRLRQWMMRITAYAdrllddl  291
            L Y A+  VNW   LGT +ANEEV +DG S+RG +PV RK +RQWM++ITAYA+RLL+DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  292  dvldWPEQVKTMQRNWIGRSTGAVALFSARAASDDGFEVDIEVFTTRPDTLFGATYLVLA  351
            + +DWPE +K MQRNWIG+STGA   F  + +     + D+ VFTTRPDTLFGATY VLA
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDT-----DKDFTVFTTRPDTLFGATYAVLA  262

Query  352  PEHDLVDELVAASWPAGVNPLWTYGGGTPGEaiaayrraiaaKSDLERQE-SREKTGVFL  410
            PEH LVD + ++                 +EA+A Y+R  + KSDL R + ++EKTGV  
Sbjct  263  PEHALVDAITTSD---------------QAEAVADYKRQASLKSDLARTDLAKEKTGVWT  307

Query  411  GSYAINPANGEPVPIFIADYVLAGYGTGAIMAVPGHDQRDWDFARAFGLPIVEVIAGGNI  470
            GSYAINP NG  +P+ IADYVLA+YGTGAIMAVP+HD+RDW+FA+ F L I+ V+ GGN+
Sbjct  308  GSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNV  367

Query  471  SESAYTGDGILVNSDYLNGMSVPAAKRAIVDRLESAGRGRARIEFKLRDWLFARQRYWGE  530
             E+A+T DG+ +NSD+L+G+  ++A   +V++LE+ G G   + ++LRDWLF+RQRYWGE
Sbjct  368  EEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGE  427

Query  531  PFPIVYDSDGRPHALDEAALPVELPDVPDYSPVLFdpddadsepsppLAKATEWVHVDLD  590
            P+PI+   DG + A+ E+ LP+ LP   D  P         +   +PLA+ T+W++V  +
Sbjct  428  PIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTDWLEVTRE  479

Query  591  LGDGLKPYSRDTNVMPQWAGSSWYELRYTDPHNSERFCAKENEAYWMGPRPAEHGPDDPG  650
              DG+K   R+TN MPQWAGSSWY LRY DPHN+E++   E    W+             
Sbjct  480  --DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWL-------------  523

Query  651  GVDLYVGGAEHAVLHLLYSRFWHKVLYDLGHVSSREPYRRLVNQGYIQAYAYTDARGSYV  710
             VD+YVGGAEHAVLHLLY+RFWHKVLYDLG V+++EP+++L NQG I + +Y D+RG+ V
Sbjct  524  PVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALV  583

Query  711  PAEQVIERGDRFVYPGPDGEVEVFQEFGKIGKSLKNSVSPDEICDAYGADTLRVYEMSMG  770
            ++++V  R++ F     + E+E  Q  +K++KSLKN V+PD++ + YGADTLRVYEM MG
Sbjct  584  ATDKVEKRDGSFFHVETGEELE--QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMG  641

Query  771  PLEASRPWATKDVVGAYRFLQRVWRLVVDEHTGETRVADGVELDIDTLRALHRTIVGVSE  830
            PL+AS +W+  ++ G+ +FL+RV RL+   +  E    ++  LD    +  + T+ +V+E
Sbjct  642  PLDASIAWSEEGLEGSRKFLDRVYRLITTKEITE---ENSGALD----KVYNETVKAVTE  694

Query  831  DFAALRNNTATAKLIEYTNHLTKKHRDAVPRAAVEPLVQMLAPLAPHIAEELWLRLGNTT  890
            +   ++ NTA A+L+ + N   K ++  +       +VQ++AP+APH++EELW  L  + 
Sbjct  695  QVDQMKFNTAIAQLMVFVNAANKEDK--LFSDYAKGFVQLIAPFAPHLGEELWQALTASG  752

Query  891  -SLAHGPFPKADAAYLVDETVEYPVQVNGKVRGRVVVAADTDEETLKAAVLTDEKVQAFL  949
             S++  P P  D + LV++ VE  VQ++GKV++++VVA D   E L+   L++EKVQA +
Sbjct  753  ESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEI  812

Query  950  AGATPRKVIVVAGRLVNLVI  969
            AG    KVI V+ +LVN+VI
Sbjct  813  AGKDIIKVIAVPNKLVNIVI  832


 Score =  129 bits (474),  Expect = 7e-31, Method: Compositional matrix adjust.
 Identities = 73/148 (50%), Positives = 99/148 (67%), Gaps = 11/148 (7%)

Query  35   LERTWQENWARLGTFNVPNPVGSLAPPDGAAVPDDKLFVQDMFPYPSGEGLHVGHPLGYI  94
            +E  WQ  WA   TF+            G+  +  K++  DMFPYPSG GLHVGHP GY 
Sbjct  9    IEPKWQAFWADNHTFKT-----------GTDASKPKFYALDMFPYPSGAGLHVGHPEGYT  57

Query  95   ATDVYARYFRMVGRNVLHALGFDAFGLPAEQYAVQTGTHPRTRTEANVVNFRRQLGRLGF  154
            ATD+ +R+ R  G+NVLH++G DAFGLPAEQYA++TG +P   T  N+ NF+RQ+  LGF
Sbjct  58   ATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGF  117

Query  155  GHDSRRSFSTTDVDFYRWTQWIFLQIYN  182
            + D  R  +TTD ++Y+WTQWIF ++Y+
Sbjct  118  SYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1543) leuS in NC_012943


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  510 bits (1924),  Expect = 2e-145, Method: Compositional matrix adjust.
 Identities = 349/740 (48%), Positives = 501/740 (68%), Gaps = 57/740 (7%)

Query  232  LVYRADSLVNWCPGLGTVLANEEVTADGRSDRGNFPVFRKRLRQWMMRITAYAdrllddl  291
            L Y A+  VNW   LGT +ANEEV +DG S+RG +PV RK +RQWM++ITAYA+RLL+DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  292  dvldWPEQVKTMQRNWIGRSTGAVALFSARAASDDGFEVDIEVFTTRPDTLFGATYLVLA  351
            + +DWPE +K MQRNWIG+STGA   F  + +     + D+ VFTTRPDTLFGATY VLA
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDT-----DKDFTVFTTRPDTLFGATYAVLA  262

Query  352  PEHDLVDELVAASWPAGVNPLWTYGGGTPGEaiaayrraiaaKSDLERQE-SREKTGVFL  410
            PEH LVD + ++                 +EA+A Y+R  + KSDL R + ++EKTGV  
Sbjct  263  PEHALVDAITTSD---------------QAEAVADYKRQASLKSDLARTDLAKEKTGVWT  307

Query  411  GSYAINPANGEPVPIFIADYVLAGYGTGAIMAVPGHDQRDWDFARAFGLPIVEVIAGGNI  470
            GSYAINP NG  +P+ IADYVLA+YGTGAIMAVP+HD+RDW+FA+ F L I+ V+ GGN+
Sbjct  308  GSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNV  367

Query  471  SESAYTGDGILVNSDYLNGMSVPAAKRAIVDRLESAGRGRARIEFKLRDWLFARQRYWGE  530
             E+A+T DG+ +NSD+L+G+  ++A   +V++LE+ G G   + ++LRDWLF+RQRYWGE
Sbjct  368  EEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGE  427

Query  531  PFPIVYDSDGRPHALDEAALPVELPDVPDYSPVLFdpddadsepsppLAKATEWVHVDLD  590
            P+PI+   DG + A+ E+ LP+ LP   D  P         +   +PLA+ T+W++V  +
Sbjct  428  PIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTDWLEVTRE  479

Query  591  LGDGLKPYSRDTNVMPQWAGSSWYELRYTDPHNSERFCAKENEAYWMGPRPAEHGPDDPG  650
              DG+K   R+TN MPQWAGSSWY LRY DPHN+E++   E    W+             
Sbjct  480  --DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWL-------------  523

Query  651  GVDLYVGGAEHAVLHLLYSRFWHKVLYDLGHVSSREPYRRLVNQGYIQAYAYTDARGSYV  710
             VD+YVGGAEHAVLHLLY+RFWHKVLYDLG V+++EP+++L NQG I + +Y D+RG+ V
Sbjct  524  PVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALV  583

Query  711  PAEQVIERGDRFVYPGPDGEVEVFQEFGKIGKSLKNSVSPDEICDAYGADTLRVYEMSMG  770
            ++++V  R++ F     + E+E  Q  +K++KSLKN V+PD++ + YGADTLRVYEM MG
Sbjct  584  ATDKVEKRDGSFFHVETGEELE--QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMG  641

Query  771  PLEASRPWATKDVVGAYRFLQRVWRLVVDEHTGETRVADGVELDIDTLRALHRTIVGVSE  830
            PL+AS +W+  ++ G+ +FL+RV RL+   +  E    ++  LD    +  + T+ +V+E
Sbjct  642  PLDASIAWSEEGLEGSRKFLDRVYRLITTKEITE---ENSGALD----KVYNETVKAVTE  694

Query  831  DFAALRNNTATAKLIEYTNHLTKKHRDAVPRAAVEPLVQMLAPLAPHIAEELWLRLGNTT  890
            +   ++ NTA A+L+ + N   K ++  +       +VQ++AP+APH++EELW  L  + 
Sbjct  695  QVDQMKFNTAIAQLMVFVNAANKEDK--LFSDYAKGFVQLIAPFAPHLGEELWQALTASG  752

Query  891  -SLAHGPFPKADAAYLVDETVEYPVQVNGKVRGRVVVAADTDEETLKAAVLTDEKVQAFL  949
             S++  P P  D + LV++ VE  VQ++GKV++++VVA D   E L+   L++EKVQA +
Sbjct  753  ESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEI  812

Query  950  AGATPRKVIVVAGRLVNLVI  969
            AG    KVI V+ +LVN+VI
Sbjct  813  AGKDIIKVIAVPNKLVNIVI  832


 Score =  129 bits (474),  Expect = 7e-31, Method: Compositional matrix adjust.
 Identities = 73/148 (50%), Positives = 99/148 (67%), Gaps = 11/148 (7%)

Query  35   LERTWQENWARLGTFNVPNPVGSLAPPDGAAVPDDKLFVQDMFPYPSGEGLHVGHPLGYI  94
            +E  WQ  WA   TF+            G+  +  K++  DMFPYPSG GLHVGHP GY 
Sbjct  9    IEPKWQAFWADNHTFKT-----------GTDASKPKFYALDMFPYPSGAGLHVGHPEGYT  57

Query  95   ATDVYARYFRMVGRNVLHALGFDAFGLPAEQYAVQTGTHPRTRTEANVVNFRRQLGRLGF  154
            ATD+ +R+ R  G+NVLH++G DAFGLPAEQYA++TG +P   T  N+ NF+RQ+  LGF
Sbjct  58   ATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGF  117

Query  155  GHDSRRSFSTTDVDFYRWTQWIFLQIYN  182
            + D  R  +TTD ++Y+WTQWIF ++Y+
Sbjct  118  SYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1544) TBSG_00040 in NC_016768


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  510 bits (1924),  Expect = 2e-145, Method: Compositional matrix adjust.
 Identities = 349/740 (48%), Positives = 501/740 (68%), Gaps = 57/740 (7%)

Query  232  LVYRADSLVNWCPGLGTVLANEEVTADGRSDRGNFPVFRKRLRQWMMRITAYAdrllddl  291
            L Y A+  VNW   LGT +ANEEV +DG S+RG +PV RK +RQWM++ITAYA+RLL+DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  292  dvldWPEQVKTMQRNWIGRSTGAVALFSARAASDDGFEVDIEVFTTRPDTLFGATYLVLA  351
            + +DWPE +K MQRNWIG+STGA   F  + +     + D+ VFTTRPDTLFGATY VLA
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDT-----DKDFTVFTTRPDTLFGATYAVLA  262

Query  352  PEHDLVDELVAASWPAGVNPLWTYGGGTPGEaiaayrraiaaKSDLERQE-SREKTGVFL  410
            PEH LVD + ++                 +EA+A Y+R  + KSDL R + ++EKTGV  
Sbjct  263  PEHALVDAITTSD---------------QAEAVADYKRQASLKSDLARTDLAKEKTGVWT  307

Query  411  GSYAINPANGEPVPIFIADYVLAGYGTGAIMAVPGHDQRDWDFARAFGLPIVEVIAGGNI  470
            GSYAINP NG  +P+ IADYVLA+YGTGAIMAVP+HD+RDW+FA+ F L I+ V+ GGN+
Sbjct  308  GSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNV  367

Query  471  SESAYTGDGILVNSDYLNGMSVPAAKRAIVDRLESAGRGRARIEFKLRDWLFARQRYWGE  530
             E+A+T DG+ +NSD+L+G+  ++A   +V++LE+ G G   + ++LRDWLF+RQRYWGE
Sbjct  368  EEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGE  427

Query  531  PFPIVYDSDGRPHALDEAALPVELPDVPDYSPVLFdpddadsepsppLAKATEWVHVDLD  590
            P+PI+   DG + A+ E+ LP+ LP   D  P         +   +PLA+ T+W++V  +
Sbjct  428  PIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTDWLEVTRE  479

Query  591  LGDGLKPYSRDTNVMPQWAGSSWYELRYTDPHNSERFCAKENEAYWMGPRPAEHGPDDPG  650
              DG+K   R+TN MPQWAGSSWY LRY DPHN+E++   E    W+             
Sbjct  480  --DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWL-------------  523

Query  651  GVDLYVGGAEHAVLHLLYSRFWHKVLYDLGHVSSREPYRRLVNQGYIQAYAYTDARGSYV  710
             VD+YVGGAEHAVLHLLY+RFWHKVLYDLG V+++EP+++L NQG I + +Y D+RG+ V
Sbjct  524  PVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALV  583

Query  711  PAEQVIERGDRFVYPGPDGEVEVFQEFGKIGKSLKNSVSPDEICDAYGADTLRVYEMSMG  770
            ++++V  R++ F     + E+E  Q  +K++KSLKN V+PD++ + YGADTLRVYEM MG
Sbjct  584  ATDKVEKRDGSFFHVETGEELE--QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMG  641

Query  771  PLEASRPWATKDVVGAYRFLQRVWRLVVDEHTGETRVADGVELDIDTLRALHRTIVGVSE  830
            PL+AS +W+  ++ G+ +FL+RV RL+   +  E    ++  LD    +  + T+ +V+E
Sbjct  642  PLDASIAWSEEGLEGSRKFLDRVYRLITTKEITE---ENSGALD----KVYNETVKAVTE  694

Query  831  DFAALRNNTATAKLIEYTNHLTKKHRDAVPRAAVEPLVQMLAPLAPHIAEELWLRLGNTT  890
            +   ++ NTA A+L+ + N   K ++  +       +VQ++AP+APH++EELW  L  + 
Sbjct  695  QVDQMKFNTAIAQLMVFVNAANKEDK--LFSDYAKGFVQLIAPFAPHLGEELWQALTASG  752

Query  891  -SLAHGPFPKADAAYLVDETVEYPVQVNGKVRGRVVVAADTDEETLKAAVLTDEKVQAFL  949
             S++  P P  D + LV++ VE  VQ++GKV++++VVA D   E L+   L++EKVQA +
Sbjct  753  ESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEI  812

Query  950  AGATPRKVIVVAGRLVNLVI  969
            AG    KVI V+ +LVN+VI
Sbjct  813  AGKDIIKVIAVPNKLVNIVI  832


 Score =  129 bits (474),  Expect = 7e-31, Method: Compositional matrix adjust.
 Identities = 73/148 (50%), Positives = 99/148 (67%), Gaps = 11/148 (7%)

Query  35   LERTWQENWARLGTFNVPNPVGSLAPPDGAAVPDDKLFVQDMFPYPSGEGLHVGHPLGYI  94
            +E  WQ  WA   TF+            G+  +  K++  DMFPYPSG GLHVGHP GY 
Sbjct  9    IEPKWQAFWADNHTFKT-----------GTDASKPKFYALDMFPYPSGAGLHVGHPEGYT  57

Query  95   ATDVYARYFRMVGRNVLHALGFDAFGLPAEQYAVQTGTHPRTRTEANVVNFRRQLGRLGF  154
            ATD+ +R+ R  G+NVLH++G DAFGLPAEQYA++TG +P   T  N+ NF+RQ+  LGF
Sbjct  58   ATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGF  117

Query  155  GHDSRRSFSTTDVDFYRWTQWIFLQIYN  182
            + D  R  +TTD ++Y+WTQWIF ++Y+
Sbjct  118  SYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1545) TBXG_000040 in NC_018078


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  510 bits (1924),  Expect = 2e-145, Method: Compositional matrix adjust.
 Identities = 349/740 (48%), Positives = 501/740 (68%), Gaps = 57/740 (7%)

Query  232  LVYRADSLVNWCPGLGTVLANEEVTADGRSDRGNFPVFRKRLRQWMMRITAYAdrllddl  291
            L Y A+  VNW   LGT +ANEEV +DG S+RG +PV RK +RQWM++ITAYA+RLL+DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  292  dvldWPEQVKTMQRNWIGRSTGAVALFSARAASDDGFEVDIEVFTTRPDTLFGATYLVLA  351
            + +DWPE +K MQRNWIG+STGA   F  + +     + D+ VFTTRPDTLFGATY VLA
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDT-----DKDFTVFTTRPDTLFGATYAVLA  262

Query  352  PEHDLVDELVAASWPAGVNPLWTYGGGTPGEaiaayrraiaaKSDLERQE-SREKTGVFL  410
            PEH LVD + ++                 +EA+A Y+R  + KSDL R + ++EKTGV  
Sbjct  263  PEHALVDAITTSD---------------QAEAVADYKRQASLKSDLARTDLAKEKTGVWT  307

Query  411  GSYAINPANGEPVPIFIADYVLAGYGTGAIMAVPGHDQRDWDFARAFGLPIVEVIAGGNI  470
            GSYAINP NG  +P+ IADYVLA+YGTGAIMAVP+HD+RDW+FA+ F L I+ V+ GGN+
Sbjct  308  GSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNV  367

Query  471  SESAYTGDGILVNSDYLNGMSVPAAKRAIVDRLESAGRGRARIEFKLRDWLFARQRYWGE  530
             E+A+T DG+ +NSD+L+G+  ++A   +V++LE+ G G   + ++LRDWLF+RQRYWGE
Sbjct  368  EEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGE  427

Query  531  PFPIVYDSDGRPHALDEAALPVELPDVPDYSPVLFdpddadsepsppLAKATEWVHVDLD  590
            P+PI+   DG + A+ E+ LP+ LP   D  P         +   +PLA+ T+W++V  +
Sbjct  428  PIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTDWLEVTRE  479

Query  591  LGDGLKPYSRDTNVMPQWAGSSWYELRYTDPHNSERFCAKENEAYWMGPRPAEHGPDDPG  650
              DG+K   R+TN MPQWAGSSWY LRY DPHN+E++   E    W+             
Sbjct  480  --DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWL-------------  523

Query  651  GVDLYVGGAEHAVLHLLYSRFWHKVLYDLGHVSSREPYRRLVNQGYIQAYAYTDARGSYV  710
             VD+YVGGAEHAVLHLLY+RFWHKVLYDLG V+++EP+++L NQG I + +Y D+RG+ V
Sbjct  524  PVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALV  583

Query  711  PAEQVIERGDRFVYPGPDGEVEVFQEFGKIGKSLKNSVSPDEICDAYGADTLRVYEMSMG  770
            ++++V  R++ F     + E+E  Q  +K++KSLKN V+PD++ + YGADTLRVYEM MG
Sbjct  584  ATDKVEKRDGSFFHVETGEELE--QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMG  641

Query  771  PLEASRPWATKDVVGAYRFLQRVWRLVVDEHTGETRVADGVELDIDTLRALHRTIVGVSE  830
            PL+AS +W+  ++ G+ +FL+RV RL+   +  E    ++  LD    +  + T+ +V+E
Sbjct  642  PLDASIAWSEEGLEGSRKFLDRVYRLITTKEITE---ENSGALD----KVYNETVKAVTE  694

Query  831  DFAALRNNTATAKLIEYTNHLTKKHRDAVPRAAVEPLVQMLAPLAPHIAEELWLRLGNTT  890
            +   ++ NTA A+L+ + N   K ++  +       +VQ++AP+APH++EELW  L  + 
Sbjct  695  QVDQMKFNTAIAQLMVFVNAANKEDK--LFSDYAKGFVQLIAPFAPHLGEELWQALTASG  752

Query  891  -SLAHGPFPKADAAYLVDETVEYPVQVNGKVRGRVVVAADTDEETLKAAVLTDEKVQAFL  949
             S++  P P  D + LV++ VE  VQ++GKV++++VVA D   E L+   L++EKVQA +
Sbjct  753  ESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEI  812

Query  950  AGATPRKVIVVAGRLVNLVI  969
            AG    KVI V+ +LVN+VI
Sbjct  813  AGKDIIKVIAVPNKLVNIVI  832


 Score =  129 bits (474),  Expect = 7e-31, Method: Compositional matrix adjust.
 Identities = 73/148 (50%), Positives = 99/148 (67%), Gaps = 11/148 (7%)

Query  35   LERTWQENWARLGTFNVPNPVGSLAPPDGAAVPDDKLFVQDMFPYPSGEGLHVGHPLGYI  94
            +E  WQ  WA   TF+            G+  +  K++  DMFPYPSG GLHVGHP GY 
Sbjct  9    IEPKWQAFWADNHTFKT-----------GTDASKPKFYALDMFPYPSGAGLHVGHPEGYT  57

Query  95   ATDVYARYFRMVGRNVLHALGFDAFGLPAEQYAVQTGTHPRTRTEANVVNFRRQLGRLGF  154
            ATD+ +R+ R  G+NVLH++G DAFGLPAEQYA++TG +P   T  N+ NF+RQ+  LGF
Sbjct  58   ATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGF  117

Query  155  GHDSRRSFSTTDVDFYRWTQWIFLQIYN  182
            + D  R  +TTD ++Y+WTQWIF ++Y+
Sbjct  118  SYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1546) leuS in NC_017026


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  510 bits (1924),  Expect = 2e-145, Method: Compositional matrix adjust.
 Identities = 349/740 (48%), Positives = 501/740 (68%), Gaps = 57/740 (7%)

Query  232  LVYRADSLVNWCPGLGTVLANEEVTADGRSDRGNFPVFRKRLRQWMMRITAYAdrllddl  291
            L Y A+  VNW   LGT +ANEEV +DG S+RG +PV RK +RQWM++ITAYA+RLL+DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  292  dvldWPEQVKTMQRNWIGRSTGAVALFSARAASDDGFEVDIEVFTTRPDTLFGATYLVLA  351
            + +DWPE +K MQRNWIG+STGA   F  + +     + D+ VFTTRPDTLFGATY VLA
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDT-----DKDFTVFTTRPDTLFGATYAVLA  262

Query  352  PEHDLVDELVAASWPAGVNPLWTYGGGTPGEaiaayrraiaaKSDLERQE-SREKTGVFL  410
            PEH LVD + ++                 +EA+A Y+R  + KSDL R + ++EKTGV  
Sbjct  263  PEHALVDAITTSD---------------QAEAVADYKRQASLKSDLARTDLAKEKTGVWT  307

Query  411  GSYAINPANGEPVPIFIADYVLAGYGTGAIMAVPGHDQRDWDFARAFGLPIVEVIAGGNI  470
            GSYAINP NG  +P+ IADYVLA+YGTGAIMAVP+HD+RDW+FA+ F L I+ V+ GGN+
Sbjct  308  GSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNV  367

Query  471  SESAYTGDGILVNSDYLNGMSVPAAKRAIVDRLESAGRGRARIEFKLRDWLFARQRYWGE  530
             E+A+T DG+ +NSD+L+G+  ++A   +V++LE+ G G   + ++LRDWLF+RQRYWGE
Sbjct  368  EEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGE  427

Query  531  PFPIVYDSDGRPHALDEAALPVELPDVPDYSPVLFdpddadsepsppLAKATEWVHVDLD  590
            P+PI+   DG + A+ E+ LP+ LP   D  P         +   +PLA+ T+W++V  +
Sbjct  428  PIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTDWLEVTRE  479

Query  591  LGDGLKPYSRDTNVMPQWAGSSWYELRYTDPHNSERFCAKENEAYWMGPRPAEHGPDDPG  650
              DG+K   R+TN MPQWAGSSWY LRY DPHN+E++   E    W+             
Sbjct  480  --DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWL-------------  523

Query  651  GVDLYVGGAEHAVLHLLYSRFWHKVLYDLGHVSSREPYRRLVNQGYIQAYAYTDARGSYV  710
             VD+YVGGAEHAVLHLLY+RFWHKVLYDLG V+++EP+++L NQG I + +Y D+RG+ V
Sbjct  524  PVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALV  583

Query  711  PAEQVIERGDRFVYPGPDGEVEVFQEFGKIGKSLKNSVSPDEICDAYGADTLRVYEMSMG  770
            ++++V  R++ F     + E+E  Q  +K++KSLKN V+PD++ + YGADTLRVYEM MG
Sbjct  584  ATDKVEKRDGSFFHVETGEELE--QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMG  641

Query  771  PLEASRPWATKDVVGAYRFLQRVWRLVVDEHTGETRVADGVELDIDTLRALHRTIVGVSE  830
            PL+AS +W+  ++ G+ +FL+RV RL+   +  E    ++  LD    +  + T+ +V+E
Sbjct  642  PLDASIAWSEEGLEGSRKFLDRVYRLITTKEITE---ENSGALD----KVYNETVKAVTE  694

Query  831  DFAALRNNTATAKLIEYTNHLTKKHRDAVPRAAVEPLVQMLAPLAPHIAEELWLRLGNTT  890
            +   ++ NTA A+L+ + N   K ++  +       +VQ++AP+APH++EELW  L  + 
Sbjct  695  QVDQMKFNTAIAQLMVFVNAANKEDK--LFSDYAKGFVQLIAPFAPHLGEELWQALTASG  752

Query  891  -SLAHGPFPKADAAYLVDETVEYPVQVNGKVRGRVVVAADTDEETLKAAVLTDEKVQAFL  949
             S++  P P  D + LV++ VE  VQ++GKV++++VVA D   E L+   L++EKVQA +
Sbjct  753  ESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEI  812

Query  950  AGATPRKVIVVAGRLVNLVI  969
            AG    KVI V+ +LVN+VI
Sbjct  813  AGKDIIKVIAVPNKLVNIVI  832


 Score =  129 bits (474),  Expect = 7e-31, Method: Compositional matrix adjust.
 Identities = 73/148 (50%), Positives = 99/148 (67%), Gaps = 11/148 (7%)

Query  35   LERTWQENWARLGTFNVPNPVGSLAPPDGAAVPDDKLFVQDMFPYPSGEGLHVGHPLGYI  94
            +E  WQ  WA   TF+            G+  +  K++  DMFPYPSG GLHVGHP GY 
Sbjct  9    IEPKWQAFWADNHTFKT-----------GTDASKPKFYALDMFPYPSGAGLHVGHPEGYT  57

Query  95   ATDVYARYFRMVGRNVLHALGFDAFGLPAEQYAVQTGTHPRTRTEANVVNFRRQLGRLGF  154
            ATD+ +R+ R  G+NVLH++G DAFGLPAEQYA++TG +P   T  N+ NF+RQ+  LGF
Sbjct  58   ATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGF  117

Query  155  GHDSRRSFSTTDVDFYRWTQWIFLQIYN  182
            + D  R  +TTD ++Y+WTQWIF ++Y+
Sbjct  118  SYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1547) leuS in NC_017528


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  510 bits (1924),  Expect = 2e-145, Method: Compositional matrix adjust.
 Identities = 349/740 (48%), Positives = 501/740 (68%), Gaps = 57/740 (7%)

Query  232  LVYRADSLVNWCPGLGTVLANEEVTADGRSDRGNFPVFRKRLRQWMMRITAYAdrllddl  291
            L Y A+  VNW   LGT +ANEEV +DG S+RG +PV RK +RQWM++ITAYA+RLL+DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  292  dvldWPEQVKTMQRNWIGRSTGAVALFSARAASDDGFEVDIEVFTTRPDTLFGATYLVLA  351
            + +DWPE +K MQRNWIG+STGA   F  + +     + D+ VFTTRPDTLFGATY VLA
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDT-----DKDFTVFTTRPDTLFGATYAVLA  262

Query  352  PEHDLVDELVAASWPAGVNPLWTYGGGTPGEaiaayrraiaaKSDLERQE-SREKTGVFL  410
            PEH LVD + ++                 +EA+A Y+R  + KSDL R + ++EKTGV  
Sbjct  263  PEHALVDAITTSD---------------QAEAVADYKRQASLKSDLARTDLAKEKTGVWT  307

Query  411  GSYAINPANGEPVPIFIADYVLAGYGTGAIMAVPGHDQRDWDFARAFGLPIVEVIAGGNI  470
            GSYAINP NG  +P+ IADYVLA+YGTGAIMAVP+HD+RDW+FA+ F L I+ V+ GGN+
Sbjct  308  GSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNV  367

Query  471  SESAYTGDGILVNSDYLNGMSVPAAKRAIVDRLESAGRGRARIEFKLRDWLFARQRYWGE  530
             E+A+T DG+ +NSD+L+G+  ++A   +V++LE+ G G   + ++LRDWLF+RQRYWGE
Sbjct  368  EEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGE  427

Query  531  PFPIVYDSDGRPHALDEAALPVELPDVPDYSPVLFdpddadsepsppLAKATEWVHVDLD  590
            P+PI+   DG + A+ E+ LP+ LP   D  P         +   +PLA+ T+W++V  +
Sbjct  428  PIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTDWLEVTRE  479

Query  591  LGDGLKPYSRDTNVMPQWAGSSWYELRYTDPHNSERFCAKENEAYWMGPRPAEHGPDDPG  650
              DG+K   R+TN MPQWAGSSWY LRY DPHN+E++   E    W+             
Sbjct  480  --DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWL-------------  523

Query  651  GVDLYVGGAEHAVLHLLYSRFWHKVLYDLGHVSSREPYRRLVNQGYIQAYAYTDARGSYV  710
             VD+YVGGAEHAVLHLLY+RFWHKVLYDLG V+++EP+++L NQG I + +Y D+RG+ V
Sbjct  524  PVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALV  583

Query  711  PAEQVIERGDRFVYPGPDGEVEVFQEFGKIGKSLKNSVSPDEICDAYGADTLRVYEMSMG  770
            ++++V  R++ F     + E+E  Q  +K++KSLKN V+PD++ + YGADTLRVYEM MG
Sbjct  584  ATDKVEKRDGSFFHVETGEELE--QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMG  641

Query  771  PLEASRPWATKDVVGAYRFLQRVWRLVVDEHTGETRVADGVELDIDTLRALHRTIVGVSE  830
            PL+AS +W+  ++ G+ +FL+RV RL+   +  E    ++  LD    +  + T+ +V+E
Sbjct  642  PLDASIAWSEEGLEGSRKFLDRVYRLITTKEITE---ENSGALD----KVYNETVKAVTE  694

Query  831  DFAALRNNTATAKLIEYTNHLTKKHRDAVPRAAVEPLVQMLAPLAPHIAEELWLRLGNTT  890
            +   ++ NTA A+L+ + N   K ++  +       +VQ++AP+APH++EELW  L  + 
Sbjct  695  QVDQMKFNTAIAQLMVFVNAANKEDK--LFSDYAKGFVQLIAPFAPHLGEELWQALTASG  752

Query  891  -SLAHGPFPKADAAYLVDETVEYPVQVNGKVRGRVVVAADTDEETLKAAVLTDEKVQAFL  949
             S++  P P  D + LV++ VE  VQ++GKV++++VVA D   E L+   L++EKVQA +
Sbjct  753  ESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEI  812

Query  950  AGATPRKVIVVAGRLVNLVI  969
            AG    KVI V+ +LVN+VI
Sbjct  813  AGKDIIKVIAVPNKLVNIVI  832


 Score =  129 bits (474),  Expect = 7e-31, Method: Compositional matrix adjust.
 Identities = 73/148 (50%), Positives = 99/148 (67%), Gaps = 11/148 (7%)

Query  35   LERTWQENWARLGTFNVPNPVGSLAPPDGAAVPDDKLFVQDMFPYPSGEGLHVGHPLGYI  94
            +E  WQ  WA   TF+            G+  +  K++  DMFPYPSG GLHVGHP GY 
Sbjct  9    IEPKWQAFWADNHTFKT-----------GTDASKPKFYALDMFPYPSGAGLHVGHPEGYT  57

Query  95   ATDVYARYFRMVGRNVLHALGFDAFGLPAEQYAVQTGTHPRTRTEANVVNFRRQLGRLGF  154
            ATD+ +R+ R  G+NVLH++G DAFGLPAEQYA++TG +P   T  N+ NF+RQ+  LGF
Sbjct  58   ATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGF  117

Query  155  GHDSRRSFSTTDVDFYRWTQWIFLQIYN  182
            + D  R  +TTD ++Y+WTQWIF ++Y+
Sbjct  118  SYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1548) MT7199_0041 in NC_020089


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  510 bits (1924),  Expect = 2e-145, Method: Compositional matrix adjust.
 Identities = 349/740 (48%), Positives = 501/740 (68%), Gaps = 57/740 (7%)

Query  232  LVYRADSLVNWCPGLGTVLANEEVTADGRSDRGNFPVFRKRLRQWMMRITAYAdrllddl  291
            L Y A+  VNW   LGT +ANEEV +DG S+RG +PV RK +RQWM++ITAYA+RLL+DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  292  dvldWPEQVKTMQRNWIGRSTGAVALFSARAASDDGFEVDIEVFTTRPDTLFGATYLVLA  351
            + +DWPE +K MQRNWIG+STGA   F  + +     + D+ VFTTRPDTLFGATY VLA
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDT-----DKDFTVFTTRPDTLFGATYAVLA  262

Query  352  PEHDLVDELVAASWPAGVNPLWTYGGGTPGEaiaayrraiaaKSDLERQE-SREKTGVFL  410
            PEH LVD + ++                 +EA+A Y+R  + KSDL R + ++EKTGV  
Sbjct  263  PEHALVDAITTSD---------------QAEAVADYKRQASLKSDLARTDLAKEKTGVWT  307

Query  411  GSYAINPANGEPVPIFIADYVLAGYGTGAIMAVPGHDQRDWDFARAFGLPIVEVIAGGNI  470
            GSYAINP NG  +P+ IADYVLA+YGTGAIMAVP+HD+RDW+FA+ F L I+ V+ GGN+
Sbjct  308  GSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNV  367

Query  471  SESAYTGDGILVNSDYLNGMSVPAAKRAIVDRLESAGRGRARIEFKLRDWLFARQRYWGE  530
             E+A+T DG+ +NSD+L+G+  ++A   +V++LE+ G G   + ++LRDWLF+RQRYWGE
Sbjct  368  EEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGE  427

Query  531  PFPIVYDSDGRPHALDEAALPVELPDVPDYSPVLFdpddadsepsppLAKATEWVHVDLD  590
            P+PI+   DG + A+ E+ LP+ LP   D  P         +   +PLA+ T+W++V  +
Sbjct  428  PIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTDWLEVTRE  479

Query  591  LGDGLKPYSRDTNVMPQWAGSSWYELRYTDPHNSERFCAKENEAYWMGPRPAEHGPDDPG  650
              DG+K   R+TN MPQWAGSSWY LRY DPHN+E++   E    W+             
Sbjct  480  --DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWL-------------  523

Query  651  GVDLYVGGAEHAVLHLLYSRFWHKVLYDLGHVSSREPYRRLVNQGYIQAYAYTDARGSYV  710
             VD+YVGGAEHAVLHLLY+RFWHKVLYDLG V+++EP+++L NQG I + +Y D+RG+ V
Sbjct  524  PVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALV  583

Query  711  PAEQVIERGDRFVYPGPDGEVEVFQEFGKIGKSLKNSVSPDEICDAYGADTLRVYEMSMG  770
            ++++V  R++ F     + E+E  Q  +K++KSLKN V+PD++ + YGADTLRVYEM MG
Sbjct  584  ATDKVEKRDGSFFHVETGEELE--QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMG  641

Query  771  PLEASRPWATKDVVGAYRFLQRVWRLVVDEHTGETRVADGVELDIDTLRALHRTIVGVSE  830
            PL+AS +W+  ++ G+ +FL+RV RL+   +  E    ++  LD    +  + T+ +V+E
Sbjct  642  PLDASIAWSEEGLEGSRKFLDRVYRLITTKEITE---ENSGALD----KVYNETVKAVTE  694

Query  831  DFAALRNNTATAKLIEYTNHLTKKHRDAVPRAAVEPLVQMLAPLAPHIAEELWLRLGNTT  890
            +   ++ NTA A+L+ + N   K ++  +       +VQ++AP+APH++EELW  L  + 
Sbjct  695  QVDQMKFNTAIAQLMVFVNAANKEDK--LFSDYAKGFVQLIAPFAPHLGEELWQALTASG  752

Query  891  -SLAHGPFPKADAAYLVDETVEYPVQVNGKVRGRVVVAADTDEETLKAAVLTDEKVQAFL  949
             S++  P P  D + LV++ VE  VQ++GKV++++VVA D   E L+   L++EKVQA +
Sbjct  753  ESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEI  812

Query  950  AGATPRKVIVVAGRLVNLVI  969
            AG    KVI V+ +LVN+VI
Sbjct  813  AGKDIIKVIAVPNKLVNIVI  832


 Score =  129 bits (474),  Expect = 7e-31, Method: Compositional matrix adjust.
 Identities = 73/148 (50%), Positives = 99/148 (67%), Gaps = 11/148 (7%)

Query  35   LERTWQENWARLGTFNVPNPVGSLAPPDGAAVPDDKLFVQDMFPYPSGEGLHVGHPLGYI  94
            +E  WQ  WA   TF+            G+  +  K++  DMFPYPSG GLHVGHP GY 
Sbjct  9    IEPKWQAFWADNHTFKT-----------GTDASKPKFYALDMFPYPSGAGLHVGHPEGYT  57

Query  95   ATDVYARYFRMVGRNVLHALGFDAFGLPAEQYAVQTGTHPRTRTEANVVNFRRQLGRLGF  154
            ATD+ +R+ R  G+NVLH++G DAFGLPAEQYA++TG +P   T  N+ NF+RQ+  LGF
Sbjct  58   ATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGF  117

Query  155  GHDSRRSFSTTDVDFYRWTQWIFLQIYN  182
            + D  R  +TTD ++Y+WTQWIF ++Y+
Sbjct  118  SYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1549) leuS in NC_016934


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  510 bits (1924),  Expect = 2e-145, Method: Compositional matrix adjust.
 Identities = 349/740 (48%), Positives = 501/740 (68%), Gaps = 57/740 (7%)

Query  232  LVYRADSLVNWCPGLGTVLANEEVTADGRSDRGNFPVFRKRLRQWMMRITAYAdrllddl  291
            L Y A+  VNW   LGT +ANEEV +DG S+RG +PV RK +RQWM++ITAYA+RLL+DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  292  dvldWPEQVKTMQRNWIGRSTGAVALFSARAASDDGFEVDIEVFTTRPDTLFGATYLVLA  351
            + +DWPE +K MQRNWIG+STGA   F  + +     + D+ VFTTRPDTLFGATY VLA
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDT-----DKDFTVFTTRPDTLFGATYAVLA  262

Query  352  PEHDLVDELVAASWPAGVNPLWTYGGGTPGEaiaayrraiaaKSDLERQE-SREKTGVFL  410
            PEH LVD + ++                 +EA+A Y+R  + KSDL R + ++EKTGV  
Sbjct  263  PEHALVDAITTSD---------------QAEAVADYKRQASLKSDLARTDLAKEKTGVWT  307

Query  411  GSYAINPANGEPVPIFIADYVLAGYGTGAIMAVPGHDQRDWDFARAFGLPIVEVIAGGNI  470
            GSYAINP NG  +P+ IADYVLA+YGTGAIMAVP+HD+RDW+FA+ F L I+ V+ GGN+
Sbjct  308  GSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNV  367

Query  471  SESAYTGDGILVNSDYLNGMSVPAAKRAIVDRLESAGRGRARIEFKLRDWLFARQRYWGE  530
             E+A+T DG+ +NSD+L+G+  ++A   +V++LE+ G G   + ++LRDWLF+RQRYWGE
Sbjct  368  EEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGE  427

Query  531  PFPIVYDSDGRPHALDEAALPVELPDVPDYSPVLFdpddadsepsppLAKATEWVHVDLD  590
            P+PI+   DG + A+ E+ LP+ LP   D  P         +   +PLA+ T+W++V  +
Sbjct  428  PIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTDWLEVTRE  479

Query  591  LGDGLKPYSRDTNVMPQWAGSSWYELRYTDPHNSERFCAKENEAYWMGPRPAEHGPDDPG  650
              DG+K   R+TN MPQWAGSSWY LRY DPHN+E++   E    W+             
Sbjct  480  --DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWL-------------  523

Query  651  GVDLYVGGAEHAVLHLLYSRFWHKVLYDLGHVSSREPYRRLVNQGYIQAYAYTDARGSYV  710
             VD+YVGGAEHAVLHLLY+RFWHKVLYDLG V+++EP+++L NQG I + +Y D+RG+ V
Sbjct  524  PVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALV  583

Query  711  PAEQVIERGDRFVYPGPDGEVEVFQEFGKIGKSLKNSVSPDEICDAYGADTLRVYEMSMG  770
            ++++V  R++ F     + E+E  Q  +K++KSLKN V+PD++ + YGADTLRVYEM MG
Sbjct  584  ATDKVEKRDGSFFHVETGEELE--QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMG  641

Query  771  PLEASRPWATKDVVGAYRFLQRVWRLVVDEHTGETRVADGVELDIDTLRALHRTIVGVSE  830
            PL+AS +W+  ++ G+ +FL+RV RL+   +  E    ++  LD    +  + T+ +V+E
Sbjct  642  PLDASIAWSEEGLEGSRKFLDRVYRLITTKEITE---ENSGALD----KVYNETVKAVTE  694

Query  831  DFAALRNNTATAKLIEYTNHLTKKHRDAVPRAAVEPLVQMLAPLAPHIAEELWLRLGNTT  890
            +   ++ NTA A+L+ + N   K ++  +       +VQ++AP+APH++EELW  L  + 
Sbjct  695  QVDQMKFNTAIAQLMVFVNAANKEDK--LFSDYAKGFVQLIAPFAPHLGEELWQALTASG  752

Query  891  -SLAHGPFPKADAAYLVDETVEYPVQVNGKVRGRVVVAADTDEETLKAAVLTDEKVQAFL  949
             S++  P P  D + LV++ VE  VQ++GKV++++VVA D   E L+   L++EKVQA +
Sbjct  753  ESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEI  812

Query  950  AGATPRKVIVVAGRLVNLVI  969
            AG    KVI V+ +LVN+VI
Sbjct  813  AGKDIIKVIAVPNKLVNIVI  832


 Score =  129 bits (474),  Expect = 7e-31, Method: Compositional matrix adjust.
 Identities = 73/148 (50%), Positives = 99/148 (67%), Gaps = 11/148 (7%)

Query  35   LERTWQENWARLGTFNVPNPVGSLAPPDGAAVPDDKLFVQDMFPYPSGEGLHVGHPLGYI  94
            +E  WQ  WA   TF+            G+  +  K++  DMFPYPSG GLHVGHP GY 
Sbjct  9    IEPKWQAFWADNHTFKT-----------GTDASKPKFYALDMFPYPSGAGLHVGHPEGYT  57

Query  95   ATDVYARYFRMVGRNVLHALGFDAFGLPAEQYAVQTGTHPRTRTEANVVNFRRQLGRLGF  154
            ATD+ +R+ R  G+NVLH++G DAFGLPAEQYA++TG +P   T  N+ NF+RQ+  LGF
Sbjct  58   ATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGF  117

Query  155  GHDSRRSFSTTDVDFYRWTQWIFLQIYN  182
            + D  R  +TTD ++Y+WTQWIF ++Y+
Sbjct  118  SYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1550) leuS in NC_017911


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  509 bits (1920),  Expect = 3e-145, Method: Compositional matrix adjust.
 Identities = 358/874 (41%), Positives = 550/874 (63%), Gaps = 58/874 (6%)

Query  5    YQPREIENAAQTFWDEQKSFEVSEQPGKETYYCLSMFPYPSGK-LHMGHVRNYTIGDVIS  63
            Y+   IE   Q+FW ++ +F  + +++K  +Y L MFPYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPMGWDAFGMPAENAAMKNNVAPAKWTYENIAYMKTQLRSLGLAVDWSR  123
            R++R  G NVL+PMGWDAFG+PAE+ AM     PA  T ENIA  K Q+ +LG++ DW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVTTCKPDYYRWEQWLFTRLFEKGVIYKKSGTVNWDPIDQTVLANEQVI-DGRGWRSGAL  182
            EV T  P+YY+W QW+FT+L+EKG+ Y     VNW     T +ANE+V+ DG + R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  IEKREIPMYYFKITAYADELLSSLDDLPGWPEQVKTMQRNWIGKSKGMEVQFPYNVDSIG  242
            + ++ +    +KITAYA+ LL  L+++ +WPE +K MQRNWIGKS G +V F  +V   +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTF--KVKDTD  240

Query  243  EAGALKVFTTRPDTLMGATYVAVAAEHPLATQAAQNNPELQAFIAECKGGSVAEADVA--  300
                + VFTTRPDTL GATY  +A+EH+L    A   ++    +A+ K  +   +D+A  
Sbjct  241  K--DFTVFTTRPDTLFGATYAVLAPEHALV--DAITTSDQAEAVADYKRQASLKSDLART  296

Query  301  --TQEKKGLPTGLFVEHPLTGEKLPVWVANYVLMHYGDGAVMAVPAHDERDFEFATKYSL  358
              ++EK G+ TG +  +P+ G  +PVW+A+YVL  YG GA+MAVPAHDERD EFA +++L
Sbjct  297  DLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNL  356

Query  359  PIKSVVRTSSGDTNPAPWQDAYGEHGTLINSGEFDGLDFQGAFDAMEVALIQKNLGASRT  418
             I +V+  ++ +      + A+ E+G  INS+ +DGLD  +A+  M   L    +G    
Sbjct  357  DIIPVLEGGNVE------EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENV  410

Query  419  QFRLRDWGISRQRYWGCPIPIIHCQTCGDVPVSEDQlpvvlpedvvpdGAG---SPLARM  475
             +RLRDW +SRQRYWG PIPIIH +     +V+E +LP+VLP       +G   SPLA +
Sbjct  411  TYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANV  470

Query  476  PEFYECSCPKCGAPAKRETDTMDTFVESSWYYARYASPHYEGGLVEKSAADHWLPVDQYI  535
             +  E +    G  ++RET+TM     SSWYY RY  PH    L +     +WLPVD Y+
Sbjct  471  TDWLEVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYV  529

Query  536  GGIEHAILHLLYARFFHKLMRDEGLVSSDEPFKNLLTQGMVIADTYYRREANGAYTWFNP  595
            GG EHA+LHLLYARF HK++ D G+V++ EPF++L+ QGM+++ +Y  R++ GA   + +
Sbjct  530  GGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY--RDSRGA---LVA  584

Query  596  ADVELERDSKAKVISAKLKADGLPVEIGGTEKMAKSKNNGVDPQSMIDQFGADTCRLFMM  655
            +D    RD+    + +   ++ L     +  KM+KS +N V+P+ +++Q+GADT R++ M
Sbjct  585  TDKVEKRDGSFFHVET---GEELE---QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEM  638

Query  656  FASPPDMSAEWSDSGVEGSHRFLKRVWRLAHA-HVSQGLPGKLDIGALNDEQKAVRRSIH  714
            F +P D S  WS+ G+EGS++FL RV RL  + ++++  +G LD            +  +
Sbjct  639  FMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALD------------KVYN  686

Query  715  LAIRQASQDVGQNHKFNTAIAQVMTLMNVLEKASQA-TEQDRALIQEGLETVTLLLAPIT  773
             +++  +++V+Q  KFNTAIAQ+M ++N  +K  +  ++  ++++Q        L+AP++
Sbjct  687  ETVKAVTEQVDQM-KFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQ--------LIAPFA  737

Query  774  PHISHELWSRLGHSGAVID-AAWPVQDDSALVQDTLQLVIQVNGKLRGQIDMPasasree  832
            PH+++ELW  L  SG  I   +WP  D+S LV++ +++V+Q++GK+++++ ++   SREE
Sbjct  738  PHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREE  797

Query  833  veaaarINENVLRFTEGLTIRKVIVVPGKLVNIV  866
            ++  A  NE+V     G  I KVI VP KLVNIV
Sbjct  798  LQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIV  831

1551) leuS in NC_017532


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  509 bits (1921),  Expect = 3e-145, Method: Compositional matrix adjust.
 Identities = 362/884 (41%), Positives = 551/884 (63%), Gaps = 74/884 (8%)

Query  5    YQPREIEAAAQSHWDSQKSFEVSEQPGKDTFYCLSMFPYPSGK-LHMGHVRNYTIGDVIA  63
            Y+   IE+  Q+ W  + +F  + +++K  FY L MFPYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMQGKNVLQPMGWDAFGMPAENAAMKNQVAPAKWTYENIAYMKAQLKSLGLAIDWSR  123
            R++R QG NVL+PMGWDAFG+PAE+ AM     PA  T ENIA  K Q+++LG++ DW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVTTCKPDYYRWEQWLFTRLFEKGVIYRKNGTVNWDPVDQTVLANEQVI-DGRGWRSGAL  182
            EV T  P+YY+W QW+FT+L+EKG+ Y  +  VNW     T +ANE+V+ DG + R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  IEKREIPMYYFKITAYAdellesldeldGWPEQVKTMQRNWIGKSRGMEISFPYDVASIG  242
            + ++ +    +KITAYA E L    E  +WPE +K MQRNWIGKS G +++F   V   +
Sbjct  184  VVRKPMRQWMLKITAYA-ERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTF--KVKDTD  240

Query  243  NEGVMKVFTTRPDTLMGATYVAVAAEHPLATLAAQNNPELQAFIDECKRGGVAEADIA--  300
            ++    VFTTRPDTL GATY  +A+EH+L  + A   ++    + + KR +   +D+A  
Sbjct  241  KD--FTVFTTRPDTLFGATYAVLAPEHAL--VDAITTSDQAEAVADYKRQASLKSDLART  296

Query  301  --TQEKKGLATSLRVQHPLTGELLPVWVANYVLMNYGEGAVMAVPAHDERDFEFASKYGL  358
              ++EK G+ T+    +P+ G  +PVW+A+YVL +YG GA+MAVPAHDERD EFA ++ L
Sbjct  297  DLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNL  356

Query  359  PIKPVVRTSAGDETPAPWQDAYGEHGQLINSGIFDGLDFEGAFDAIEVALQKKGLGQART  418
             I PV+  +  +E+      A+ E+G  INS+++DGLD  +A+  +   L+  G+G+   
Sbjct  357  DIIPVLEGGNVEEA------AFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENV  410

Query  419  QFRLRDWGISRQRYWGCPIPIIHCDSCGDVPVPEDQlpvvlpedvvpdGAG---SPLARM  475
             +RLRDW +SRQRYWG PIPIIH +     +VPE +LP+VLP       +G   SPLA +
Sbjct  411  TYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANV  470

Query  476  PEFYECTCPKCGAPAKRETDTMDTFVESSWYFARYASPNYDKGMVDPQAANHWLPVDQYI  535
             +  E T    G  ++RET+TM     SSWY+ RY  P+    + D +  ++WLPVD Y+
Sbjct  471  TDWLEVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYV  529

Query  536  GGIEHAILHLLYARFFHKLMRDEGLVSSNEPFKNLLTQGMVVAETYYRTLENGGKDWFNP  595
            GG EHA+LHLLYARF HK++ D G+V+++EPF++L+ QGM+++ +Y              
Sbjct  530  GGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY--------------  575

Query  596  ADVEVERDAKAKVIGARL--KTDG--LPVEIG-----GTEKMSKSKNNGVDPQAMIDAYG  646
                  RD+++ ++++    K DG  + VE G     +  KMSKS +N V+P+ +++ YG
Sbjct  576  ------RDSRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYG  629

Query  647  ADTCRLFMMFASPPDMSLEWSDSGVEGASRFLRRVWRLAHA-HVSAGLPGALDVAALNDE  705
            ADT R++ MF +P D S+ WS+ G+EG+ +FL RV RL  + +++   +GALD       
Sbjct  630  ADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALD-------  682

Query  706  QKAVRRAIHLAIKQASTDVGQHHKFNTAIAQVMTLMNVLEKAPTAGEQDRALLQEGLETV  765
                 +  + ++K  + +V ++ KFNTAIAQ+M ++N       A++++  L+ +     
Sbjct  683  -----KVYNETVKAVTEQV-DQMKFNTAIAQLMVFVN-------AANKEDKLFSDYAKGF  729

Query  766  ALLLAPITPHICHELWQQLGKPGAIID-AQWPKVDEAALVQDSLTLVVQVNGKLRGQIEV  824
              L+AP++PH+ +ELWQ L  +G  I    WP  DE+ LV++ + +VVQ++GK+++++ V
Sbjct  730  VQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVV  789

Query  825  PASASREEVETAARGNENVLRFTEGLTIRKVIVVPGKLVNIVAN  868
            +   SREE++  A +NE+V     G  I KVI VP KLVNIV +
Sbjct  790  AKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

1552) leuS in NC_017531


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  508 bits (1918),  Expect = 4e-145, Method: Compositional matrix adjust.
 Identities = 354/866 (41%), Positives = 543/866 (63%), Gaps = 48/866 (5%)

Query  5    YRPEEIESRVQQQWDENETFKVTEQEGKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIA  63
            Y    IE++ Q  W +N+TFK   + +K K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKLLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCQPEYYRWEQWFFTKLYEKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T +P+YY+W QW+FTKLYEKGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITDYAeellndldtleeWPEQVKTMQRNWIGRSEGVEITFDVADSLEK  242
            V RK + QW +KIT YA E L +     +WPE +K MQRNWIG+S G ++TF V D+   
Sbjct  184  VVRKPMRQWMLKITAYA-ERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  VTVYTTRPDTFYGATYVavaaghplalqaaasnpalaDFIAECRNTKVAEADMA----TM  298
             TV+TTRPDT++GATY     +   AL  A + +  A+ +A+ +      +D+A    + 
Sbjct  243  FTVFTTRPDTLFGATYA--VLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  299  EKKGMATGLSAVHPLTGEAVPVWVANFVLMEYGTGAVMAVPAHDQRDWEFATKYDLPIKP  358
            EK G+ TG  A++P+ G  +PVW+A++VL  YGTGA+MAVPAHD+RDWEFA +++L I P
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VILNLDGSEPDVSTGAMTDKGTLFNSAECSGLDHSAGFNAIADALAAKGVGVRKVNYRLR  418
            V   L+G+  +V  +A T+ G  +NS    GLD ++++  + + L A GVG  +V YRLR
Sbjct  361  V---LEGG--NVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  419  DWGVSRQRYWGAPIPMVTLEDGTVMPTPEDQLPVILP--EDVVMDGIT-SPIKADPEWAK  475
            DW  SRQRYWG PIP++  EDGT  + PE +LP++LP   D+   G   SP+    +W  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  476  TT-VNGQPALRETDTFDTFMESSWYYARYTCADYKDGMLDPAAANYWLPVDQYVGGIEHA  534
             T  +G  + RET+T      SSWYY RY  ++  + + D    + WLPVD YVGG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  535  IMHLMYFRFFHKLLRDAGLVNSNEPAKRLLCQGMVLADAFYYLGVNGERNWVSPVDVTVE  594
            ++HL+Y RF HK+L D G+V ++EP ++L+ QGM+L+ ++        R+  +++ V+ +
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY--------RDSRGAL-VATD  586

Query  595  RDEKGRITKAVDTQGREVIYAGMSKMSKSKNNGIDPQLMVERYGADTVRLFMMFASPADM  654
            + EK R     + +  E +  + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D 
Sbjct  587  KVEK-RDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  655  TLEWQESGVEGANRFLKRVWKLAYDHSQKGATVALDVASLNDDQKGLRRDLHKTIAKVSD  714
            ++ W E G+EG+ +FL RV +L    + K  T        +++  +L +  + T+  V++
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLI---TTKEIT--------EENSGALDKVYNETVKAVTE  694

Query  715  DIGRRQTFNTAIAAVMELMNKLTRAPQDSEQDRALMQEALLAVTRLLYPFTPHACFVLWQ  774
            ++++ + FNTAIA +M ++N        ++++  L  +   +  +L+ PF+PH    LWQ
Sbjct  695  QVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  775  TLGGQG-TIDNAEWPVADDAAMVEDALLVVVQVNGKVRGKITVAADATQEQVQARAAEEP  833
            +L + G +I    WP  D++ +VE+ + +VVQ++GKV++K+ VA D ++E++Q  A  + 
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  834  LVAKYLDGVSIRKVIYVPGKLLNLVV  859
             V   + G  I KVI VP KL+N+V+
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVI  832

1553) PAGR_g3028 in NC_017554


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  508 bits (1918),  Expect = 4e-145, Method: Compositional matrix adjust.
 Identities = 354/866 (41%), Positives = 543/866 (63%), Gaps = 48/866 (5%)

Query  5    YRPEEIESRVQQQWDENETFKVTEQEGKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIA  63
            Y    IE++ Q  W +N+TFK   + +K K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKLLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCQPEYYRWEQWFFTKLYEKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T +P+YY+W QW+FTKLYEKGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITDYAeellndldtleeWPEQVKTMQRNWIGRSEGVEITFDVADSLEK  242
            V RK + QW +KIT YA E L +     +WPE +K MQRNWIG+S G ++TF V D+   
Sbjct  184  VVRKPMRQWMLKITAYA-ERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  VTVYTTRPDTFYGATYVavaaghplalqaaasnpalaDFIAECRNTKVAEADMA----TM  298
             TV+TTRPDT++GATY     +   AL  A + +  A+ +A+ +      +D+A    + 
Sbjct  243  FTVFTTRPDTLFGATYA--VLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  299  EKKGMATGLSAVHPLTGEAVPVWVANFVLMEYGTGAVMAVPAHDQRDWEFATKYDLPIKP  358
            EK G+ TG  A++P+ G  +PVW+A++VL  YGTGA+MAVPAHD+RDWEFA +++L I P
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VILNLDGSEPDVSTGAMTDKGTLFNSAECSGLDHSAGFNAIADALAAKGVGVRKVNYRLR  418
            V   L+G+  +V  +A T+ G  +NS    GLD ++++  + + L A GVG  +V YRLR
Sbjct  361  V---LEGG--NVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  419  DWGVSRQRYWGAPIPMVTLEDGTVMPTPEDQLPVILP--EDVVMDGIT-SPIKADPEWAK  475
            DW  SRQRYWG PIP++  EDGT  + PE +LP++LP   D+   G   SP+    +W  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  476  TT-VNGQPALRETDTFDTFMESSWYYARYTCADYKDGMLDPAAANYWLPVDQYVGGIEHA  534
             T  +G  + RET+T      SSWYY RY  ++  + + D    + WLPVD YVGG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  535  IMHLMYFRFFHKLLRDAGLVNSNEPAKRLLCQGMVLADAFYYLGVNGERNWVSPVDVTVE  594
            ++HL+Y RF HK+L D G+V ++EP ++L+ QGM+L+ ++        R+  +++ V+ +
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY--------RDSRGAL-VATD  586

Query  595  RDEKGRITKAVDTQGREVIYAGMSKMSKSKNNGIDPQLMVERYGADTVRLFMMFASPADM  654
            + EK R     + +  E +  + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D 
Sbjct  587  KVEK-RDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  655  TLEWQESGVEGANRFLKRVWKLAYDHSQKGATVALDVASLNDDQKGLRRDLHKTIAKVSD  714
            ++ W E G+EG+ +FL RV +L    + K  T        +++  +L +  + T+  V++
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLI---TTKEIT--------EENSGALDKVYNETVKAVTE  694

Query  715  DIGRRQTFNTAIAAVMELMNKLTRAPQDSEQDRALMQEALLAVTRLLYPFTPHACFVLWQ  774
            ++++ + FNTAIA +M ++N        ++++  L  +   +  +L+ PF+PH    LWQ
Sbjct  695  QVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  775  TLGGQG-TIDNAEWPVADDAAMVEDALLVVVQVNGKVRGKITVAADATQEQVQARAAEEP  833
            +L + G +I    WP  D++ +VE+ + +VVQ++GKV++K+ VA D ++E++Q  A  + 
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  834  LVAKYLDGVSIRKVIYVPGKLLNLVV  859
             V   + G  I KVI VP KL+N+V+
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVI  832

1554) leuS in NC_016816


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  508 bits (1918),  Expect = 4e-145, Method: Compositional matrix adjust.
 Identities = 354/866 (41%), Positives = 543/866 (63%), Gaps = 48/866 (5%)

Query  5    YRPEEIESRVQQQWDENETFKVTEQEGKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIA  63
            Y    IE++ Q  W +N+TFK   + +K K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKLLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCQPEYYRWEQWFFTKLYEKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T +P+YY+W QW+FTKLYEKGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITDYAeellndldtleeWPEQVKTMQRNWIGRSEGVEITFDVADSLEK  242
            V RK + QW +KIT YA E L +     +WPE +K MQRNWIG+S G ++TF V D+   
Sbjct  184  VVRKPMRQWMLKITAYA-ERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  VTVYTTRPDTFYGATYVavaaghplalqaaasnpalaDFIAECRNTKVAEADMA----TM  298
             TV+TTRPDT++GATY     +   AL  A + +  A+ +A+ +      +D+A    + 
Sbjct  243  FTVFTTRPDTLFGATYA--VLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  299  EKKGMATGLSAVHPLTGEAVPVWVANFVLMEYGTGAVMAVPAHDQRDWEFATKYDLPIKP  358
            EK G+ TG  A++P+ G  +PVW+A++VL  YGTGA+MAVPAHD+RDWEFA +++L I P
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VILNLDGSEPDVSTGAMTDKGTLFNSAECSGLDHSAGFNAIADALAAKGVGVRKVNYRLR  418
            V   L+G+  +V  +A T+ G  +NS    GLD ++++  + + L A GVG  +V YRLR
Sbjct  361  V---LEGG--NVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  419  DWGVSRQRYWGAPIPMVTLEDGTVMPTPEDQLPVILP--EDVVMDGIT-SPIKADPEWAK  475
            DW  SRQRYWG PIP++  EDGT  + PE +LP++LP   D+   G   SP+    +W  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  476  TT-VNGQPALRETDTFDTFMESSWYYARYTCADYKDGMLDPAAANYWLPVDQYVGGIEHA  534
             T  +G  + RET+T      SSWYY RY  ++  + + D    + WLPVD YVGG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  535  IMHLMYFRFFHKLLRDAGLVNSNEPAKRLLCQGMVLADAFYYLGVNGERNWVSPVDVTVE  594
            ++HL+Y RF HK+L D G+V ++EP ++L+ QGM+L+ ++        R+  +++ V+ +
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY--------RDSRGAL-VATD  586

Query  595  RDEKGRITKAVDTQGREVIYAGMSKMSKSKNNGIDPQLMVERYGADTVRLFMMFASPADM  654
            + EK R     + +  E +  + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D 
Sbjct  587  KVEK-RDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  655  TLEWQESGVEGANRFLKRVWKLAYDHSQKGATVALDVASLNDDQKGLRRDLHKTIAKVSD  714
            ++ W E G+EG+ +FL RV +L    + K  T        +++  +L +  + T+  V++
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLI---TTKEIT--------EENSGALDKVYNETVKAVTE  694

Query  715  DIGRRQTFNTAIAAVMELMNKLTRAPQDSEQDRALMQEALLAVTRLLYPFTPHACFVLWQ  774
            ++++ + FNTAIA +M ++N        ++++  L  +   +  +L+ PF+PH    LWQ
Sbjct  695  QVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  775  TLGGQG-TIDNAEWPVADDAAMVEDALLVVVQVNGKVRGKITVAADATQEQVQARAAEEP  833
            +L + G +I    WP  D++ +VE+ + +VVQ++GKV++K+ VA D ++E++Q  A  + 
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  834  LVAKYLDGVSIRKVIYVPGKLLNLVV  859
             V   + G  I KVI VP KL+N+V+
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVI  832

1555) leuS in NC_007005


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  508 bits (1918),  Expect = 4e-145, Method: Compositional matrix adjust.
 Identities = 352/874 (41%), Positives = 548/874 (63%), Gaps = 56/874 (6%)

Query  4    LYQPREIEAAAQTFWDEQKSFEVSEQPGKDTFYCLSMFPYPSGK-LHMGHVRNYTIGDVI  62
            +Y+   IE+  Q+FW ++ +F  + +++K  FY L MFPYPSG  LH+GH   YT  D++
Sbjct  3    FYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDIL  62

Query  63   SRYQRMLGKNVLQPLGWDAFGMPAENAAIDNNVAPAKWTYENIDYMKTQLKSLGLAVDWS  122
            SR++R  G NVL+P+GWDAFG+PAE+ A+D    PA  T ENI   K Q+++LG++ DW 
Sbjct  63   SRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWD  122

Query  123  REVTTCKPDYYRWEQWLFTRLFEKGVIYRKNGTVNWDPIDQTVLANEQVI-DGRGWRSGA  181
            REV T  P+YY+W QW+FT+L+EKG+ Y  +  VNW     T +ANE+V+ DG + R+G 
Sbjct  123  REVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGY  182

Query  182  LIEKREIPMYYFKITAYADELLESLDELPGWPEQVKTMQRNWIGRSRGMEVQFPYDQASI  241
             + ++ +    +KITAYA+ LLE L+E+ +WPE +K MQRNWIG+S G +V F   ++  
Sbjct  183  PVVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTD-  240

Query  242  GEAGALKVFTTRPDTLMGATYVAVAAEHPLATLAAQGNPALQAFIDECKGGSVAEADVA-  300
                 + VFTTRPDTL GATY  +A+EH+L    + ++ A    + + K  +   +D+A 
Sbjct  241  ---KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQA--EAVADYKRQASLKSDLAR  295

Query  301  ---TQEKKGQATSLFVEHPLTGEKLPVWVANYVLMHYGDGAVMAVPAHDERDFEFATQYG  357
               ++EK G  T+ +  +P+ G  +PVW+A+YVL  YG GA+MAVPAHDERD EFA Q+ 
Sbjct  296  TDLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFN  355

Query  358  LPIKPVVRTSAGDQTPAPWQPAYGEHGELINSGEFTGLTFQDAFDAIEAALVKKSLGQSR  417
            L I PV+  +  +++      A+ E+G  INS+ + GL    A+  +   L   ++G+  
Sbjct  356  LDIIPVLEGGNVEEA------AFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNEN  409

Query  418  TQFRLRDWGISRQRYWGCPIPIVHCDTCGDVPVPEDQlpvvlpedvvpdGAG---SPLAR  474
              +RLRDW +SRQRYWG PIPI+H +     +VPE +LP+VLP       +G   SPLA 
Sbjct  410  VTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLAN  469

Query  475  MPEFYECSCPKCGAPAKRETDTMDTFVESSWYYARYASPHYEGGLVEPNAANHWLPVDQY  534
            + +  E +    G  ++RET+TM     SSWYY RY  PH    L + +  ++WLPVD Y
Sbjct  470  VTDWLEVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIY  528

Query  535  IGGIEHAILHLLYARFFHKLMRDEGLVTSNEPFKNLLTQGMVNAETYFRMETSGKKTWIN  594
            +GG EHA+LHLLYARF HK++ D G+V ++EPF++L+ QGM+ + +Y   ++ G    + 
Sbjct  529  VGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY--RDSRGA---LV  583

Query  595  PADVTLERDAKAKVISARLTSDGLPVEIGGTEKMSKSKKNGIDPQTMIDQYGADTCRLFM  654
            ++D    RD+    +    T++ L     +  KMSKS KN ++P+ +++QYGADT R++ 
Sbjct  584  ATDKVEKRDGSFFHVE---TGEELE---QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYE  637

Query  655  MFASPPDMSLEWSDSGVEGSHRFLRRVWRLAQA-HVTQGPSTGLDVAALSDEQKAIRRAI  713
            MF +P D S+ WS+ G+EGS++FL RV RL  + ++T+  S +LD            +  
Sbjct  638  MFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALD------------KVY  685

Query  714  HQAIRQASQDIGQNQKFNTAVAQVMTLMNVLEKAPQDTPQDRALMQEGVETVALLLAPIT  773
            +++++  +++++Q  KFNTA+AQ+M ++N  +K       +  L  +       L+AP++
Sbjct  686  NETVKAVTEQVDQ-MKFNTAIAQLMVFVNAANK-------EDKLFSDYAKGFVQLIAPFA  737

Query  774  PHISHELWKQL-GHNEPVIDAGWPAFDASALVQDSLQLVIQVNGKLRGHIEMPasasree  832
            PH+++ELW+ L +  E++    WP++D S LV++ +++V+Q++GK+++ + ++   SREE
Sbjct  738  PHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREE  797

Query  833  veaaarvnenVLRFTDGLTIRKVIVVPGKLVNIV  866
            ++  A  NE+V     G  I KVI VP KLVNIV
Sbjct  798  LQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIV  831

1556) leuS in NC_021054


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  508 bits (1918),  Expect = 5e-145, Method: Compositional matrix adjust.
 Identities = 349/740 (48%), Positives = 500/740 (68%), Gaps = 57/740 (7%)

Query  232  LVYRADSLVNWCPGLGTVLANEEVTADGRSDRGNFPVFRKRLRQWMMRITAYAdrllddl  291
            L Y A+  VNW   LGT +ANEEV +DG S+RG +PV RK +RQWM++ITAYA+RLL+DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  292  dvldWPEQVKTMQRNWIGRSTGAVALFSARAASDDGFEVDIEVFTTRPDTLFGATYLVLA  351
            + +DWPE +K MQRNWIG+STGA   F  + +     + D+ VFTTRPDTLFGATY VLA
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDT-----DKDFTVFTTRPDTLFGATYAVLA  262

Query  352  PEHDLVDELVAASWPAGVNPLWTYGGGTPGEaiaayrraiaaKSDLERQE-SGEKTGVFL  410
            PEH LVD + ++                 +EA+A Y+R  + KSDL R + + EKTGV  
Sbjct  263  PEHALVDAITTSD---------------QAEAVADYKRQASLKSDLARTDLAKEKTGVWT  307

Query  411  GSYAINPANGEPVPIFIADYVLAGYGTGAIMAVPGHDQRDWDFARAFGLPIVEVIAGGNI  470
            GSYAINP NG  +P+ IADYVLA+YGTGAIMAVP+HD+RDW+FA+ F L I+ V+ GGN+
Sbjct  308  GSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNV  367

Query  471  SESAYTGDGILVNSDYLNGMSVPAAKRAIVDRLESAGRGRARIEFKLRDWLFARQRYWGE  530
             E+A+T DG+ +NSD+L+G+  ++A   +V++LE+ G G   + ++LRDWLF+RQRYWGE
Sbjct  368  EEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGE  427

Query  531  PFPIVYDSDGRPHALDEAALPVELPDVPDYSPVLFdpddadsepsppLAKATEWVHVDLD  590
            P+PI+   DG + A+ E+ LP+ LP   D  P         +   +PLA+ T+W++V  +
Sbjct  428  PIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTDWLEVTRE  479

Query  591  LGDGLKPYSRDTNVMPQWAGSSWYELRYTDPHNSERFCAKENEAYWMGPRPAEHGPDDPG  650
              DG+K   R+TN MPQWAGSSWY LRY DPHN+E++   E    W+             
Sbjct  480  --DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWL-------------  523

Query  651  GVDLYVGGAEHAVLHLLYSRFWHKVLYDLGHVSSREPYRRLVNQGYIQAYAYTDARGSYV  710
             VD+YVGGAEHAVLHLLY+RFWHKVLYDLG V+++EP+++L NQG I + +Y D+RG+ V
Sbjct  524  PVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALV  583

Query  711  PAEQVIERGDRFVYPGPDGEVEVFQEFGKIGKSLKNSVSPDEICDAYGADTLRVYEMSMG  770
            ++++V  R++ F     + E+E  Q  +K++KSLKN V+PD++ + YGADTLRVYEM MG
Sbjct  584  ATDKVEKRDGSFFHVETGEELE--QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMG  641

Query  771  PLEASRPWATKDVVGAYRFLQRVWRLVVDEHTGETRVADGVELDIDTLRALHRTIVGVSE  830
            PL+AS +W+  ++ G+ +FL+RV RL+   +  E    ++  LD    +  + T+ +V+E
Sbjct  642  PLDASIAWSEEGLEGSRKFLDRVYRLITTKEITE---ENSGALD----KVYNETVKAVTE  694

Query  831  DFAALRNNTATAKLIEYTNHLTKKHRDAVPRAAVEPLVQMLAPLAPHIAEELWLRLGNTT  890
            +   ++ NTA A+L+ + N   K ++  +       +VQ++AP+APH++EELW  L  + 
Sbjct  695  QVDQMKFNTAIAQLMVFVNAANKEDK--LFSDYAKGFVQLIAPFAPHLGEELWQALTASG  752

Query  891  -SLAHGPFPKADAAYLVDETVEYPVQVNGKVRGRVVVAADTDEETLKAAVLTDEKVQAFL  949
             S++  P P  D + LV++ VE  VQ++GKV++++VVA D   E L+   L++EKVQA +
Sbjct  753  ESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEI  812

Query  950  AGATPRKVIVVAGRLVNLVI  969
            AG    KVI V+ +LVN+VI
Sbjct  813  AGKDIIKVIAVPNKLVNIVI  832


 Score =  129 bits (474),  Expect = 7e-31, Method: Compositional matrix adjust.
 Identities = 73/148 (50%), Positives = 99/148 (67%), Gaps = 11/148 (7%)

Query  35   LERTWQENWARLGTFNVPNPVGSLAPPDGAAVPDDKLFVQDMFPYPSGEGLHVGHPLGYI  94
            +E  WQ  WA   TF+            G+  +  K++  DMFPYPSG GLHVGHP GY 
Sbjct  9    IEPKWQAFWADNHTFKT-----------GTDASKPKFYALDMFPYPSGAGLHVGHPEGYT  57

Query  95   ATDVYARYFRMVGRNVLHALGFDAFGLPAEQYAVQTGTHPRTRTEANVVNFRRQLGRLGF  154
            ATD+ +R+ R  G+NVLH++G DAFGLPAEQYA++TG +P   T  N+ NF+RQ+  LGF
Sbjct  58   ATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGF  117

Query  155  GHDSRRSFSTTDVDFYRWTQWIFLQIYN  182
            + D  R  +TTD ++Y+WTQWIF ++Y+
Sbjct  118  SYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1557) CCDC5079_0038 in NC_017523


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  508 bits (1918),  Expect = 5e-145, Method: Compositional matrix adjust.
 Identities = 349/740 (48%), Positives = 500/740 (68%), Gaps = 57/740 (7%)

Query  232  LVYRADSLVNWCPGLGTVLANEEVTADGRSDRGNFPVFRKRLRQWMMRITAYAdrllddl  291
            L Y A+  VNW   LGT +ANEEV +DG S+RG +PV RK +RQWM++ITAYA+RLL+DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  292  dvldWPEQVKTMQRNWIGRSTGAVALFSARAASDDGFEVDIEVFTTRPDTLFGATYLVLA  351
            + +DWPE +K MQRNWIG+STGA   F  + +     + D+ VFTTRPDTLFGATY VLA
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDT-----DKDFTVFTTRPDTLFGATYAVLA  262

Query  352  PEHDLVDELVAASWPAGVNPLWTYGGGTPGEaiaayrraiaaKSDLERQE-SGEKTGVFL  410
            PEH LVD + ++                 +EA+A Y+R  + KSDL R + + EKTGV  
Sbjct  263  PEHALVDAITTSD---------------QAEAVADYKRQASLKSDLARTDLAKEKTGVWT  307

Query  411  GSYAINPANGEPVPIFIADYVLAGYGTGAIMAVPGHDQRDWDFARAFGLPIVEVIAGGNI  470
            GSYAINP NG  +P+ IADYVLA+YGTGAIMAVP+HD+RDW+FA+ F L I+ V+ GGN+
Sbjct  308  GSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNV  367

Query  471  SESAYTGDGILVNSDYLNGMSVPAAKRAIVDRLESAGRGRARIEFKLRDWLFARQRYWGE  530
             E+A+T DG+ +NSD+L+G+  ++A   +V++LE+ G G   + ++LRDWLF+RQRYWGE
Sbjct  368  EEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGE  427

Query  531  PFPIVYDSDGRPHALDEAALPVELPDVPDYSPVLFdpddadsepsppLAKATEWVHVDLD  590
            P+PI+   DG + A+ E+ LP+ LP   D  P         +   +PLA+ T+W++V  +
Sbjct  428  PIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTDWLEVTRE  479

Query  591  LGDGLKPYSRDTNVMPQWAGSSWYELRYTDPHNSERFCAKENEAYWMGPRPAEHGPDDPG  650
              DG+K   R+TN MPQWAGSSWY LRY DPHN+E++   E    W+             
Sbjct  480  --DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWL-------------  523

Query  651  GVDLYVGGAEHAVLHLLYSRFWHKVLYDLGHVSSREPYRRLVNQGYIQAYAYTDARGSYV  710
             VD+YVGGAEHAVLHLLY+RFWHKVLYDLG V+++EP+++L NQG I + +Y D+RG+ V
Sbjct  524  PVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALV  583

Query  711  PAEQVIERGDRFVYPGPDGEVEVFQEFGKIGKSLKNSVSPDEICDAYGADTLRVYEMSMG  770
            ++++V  R++ F     + E+E  Q  +K++KSLKN V+PD++ + YGADTLRVYEM MG
Sbjct  584  ATDKVEKRDGSFFHVETGEELE--QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMG  641

Query  771  PLEASRPWATKDVVGAYRFLQRVWRLVVDEHTGETRVADGVELDIDTLRALHRTIVGVSE  830
            PL+AS +W+  ++ G+ +FL+RV RL+   +  E    ++  LD    +  + T+ +V+E
Sbjct  642  PLDASIAWSEEGLEGSRKFLDRVYRLITTKEITE---ENSGALD----KVYNETVKAVTE  694

Query  831  DFAALRNNTATAKLIEYTNHLTKKHRDAVPRAAVEPLVQMLAPLAPHIAEELWLRLGNTT  890
            +   ++ NTA A+L+ + N   K ++  +       +VQ++AP+APH++EELW  L  + 
Sbjct  695  QVDQMKFNTAIAQLMVFVNAANKEDK--LFSDYAKGFVQLIAPFAPHLGEELWQALTASG  752

Query  891  -SLAHGPFPKADAAYLVDETVEYPVQVNGKVRGRVVVAADTDEETLKAAVLTDEKVQAFL  949
             S++  P P  D + LV++ VE  VQ++GKV++++VVA D   E L+   L++EKVQA +
Sbjct  753  ESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEI  812

Query  950  AGATPRKVIVVAGRLVNLVI  969
            AG    KVI V+ +LVN+VI
Sbjct  813  AGKDIIKVIAVPNKLVNIVI  832


 Score =  129 bits (474),  Expect = 7e-31, Method: Compositional matrix adjust.
 Identities = 73/148 (50%), Positives = 99/148 (67%), Gaps = 11/148 (7%)

Query  35   LERTWQENWARLGTFNVPNPVGSLAPPDGAAVPDDKLFVQDMFPYPSGEGLHVGHPLGYI  94
            +E  WQ  WA   TF+            G+  +  K++  DMFPYPSG GLHVGHP GY 
Sbjct  9    IEPKWQAFWADNHTFKT-----------GTDASKPKFYALDMFPYPSGAGLHVGHPEGYT  57

Query  95   ATDVYARYFRMVGRNVLHALGFDAFGLPAEQYAVQTGTHPRTRTEANVVNFRRQLGRLGF  154
            ATD+ +R+ R  G+NVLH++G DAFGLPAEQYA++TG +P   T  N+ NF+RQ+  LGF
Sbjct  58   ATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGF  117

Query  155  GHDSRRSFSTTDVDFYRWTQWIFLQIYN  182
            + D  R  +TTD ++Y+WTQWIF ++Y+
Sbjct  118  SYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1558) leuS in NC_021251


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  508 bits (1918),  Expect = 5e-145, Method: Compositional matrix adjust.
 Identities = 349/740 (48%), Positives = 500/740 (68%), Gaps = 57/740 (7%)

Query  232  LVYRADSLVNWCPGLGTVLANEEVTADGRSDRGNFPVFRKRLRQWMMRITAYAdrllddl  291
            L Y A+  VNW   LGT +ANEEV +DG S+RG +PV RK +RQWM++ITAYA+RLL+DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  292  dvldWPEQVKTMQRNWIGRSTGAVALFSARAASDDGFEVDIEVFTTRPDTLFGATYLVLA  351
            + +DWPE +K MQRNWIG+STGA   F  + +     + D+ VFTTRPDTLFGATY VLA
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDT-----DKDFTVFTTRPDTLFGATYAVLA  262

Query  352  PEHDLVDELVAASWPAGVNPLWTYGGGTPGEaiaayrraiaaKSDLERQE-SGEKTGVFL  410
            PEH LVD + ++                 +EA+A Y+R  + KSDL R + + EKTGV  
Sbjct  263  PEHALVDAITTSD---------------QAEAVADYKRQASLKSDLARTDLAKEKTGVWT  307

Query  411  GSYAINPANGEPVPIFIADYVLAGYGTGAIMAVPGHDQRDWDFARAFGLPIVEVIAGGNI  470
            GSYAINP NG  +P+ IADYVLA+YGTGAIMAVP+HD+RDW+FA+ F L I+ V+ GGN+
Sbjct  308  GSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNV  367

Query  471  SESAYTGDGILVNSDYLNGMSVPAAKRAIVDRLESAGRGRARIEFKLRDWLFARQRYWGE  530
             E+A+T DG+ +NSD+L+G+  ++A   +V++LE+ G G   + ++LRDWLF+RQRYWGE
Sbjct  368  EEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGE  427

Query  531  PFPIVYDSDGRPHALDEAALPVELPDVPDYSPVLFdpddadsepsppLAKATEWVHVDLD  590
            P+PI+   DG + A+ E+ LP+ LP   D  P         +   +PLA+ T+W++V  +
Sbjct  428  PIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTDWLEVTRE  479

Query  591  LGDGLKPYSRDTNVMPQWAGSSWYELRYTDPHNSERFCAKENEAYWMGPRPAEHGPDDPG  650
              DG+K   R+TN MPQWAGSSWY LRY DPHN+E++   E    W+             
Sbjct  480  --DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWL-------------  523

Query  651  GVDLYVGGAEHAVLHLLYSRFWHKVLYDLGHVSSREPYRRLVNQGYIQAYAYTDARGSYV  710
             VD+YVGGAEHAVLHLLY+RFWHKVLYDLG V+++EP+++L NQG I + +Y D+RG+ V
Sbjct  524  PVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALV  583

Query  711  PAEQVIERGDRFVYPGPDGEVEVFQEFGKIGKSLKNSVSPDEICDAYGADTLRVYEMSMG  770
            ++++V  R++ F     + E+E  Q  +K++KSLKN V+PD++ + YGADTLRVYEM MG
Sbjct  584  ATDKVEKRDGSFFHVETGEELE--QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMG  641

Query  771  PLEASRPWATKDVVGAYRFLQRVWRLVVDEHTGETRVADGVELDIDTLRALHRTIVGVSE  830
            PL+AS +W+  ++ G+ +FL+RV RL+   +  E    ++  LD    +  + T+ +V+E
Sbjct  642  PLDASIAWSEEGLEGSRKFLDRVYRLITTKEITE---ENSGALD----KVYNETVKAVTE  694

Query  831  DFAALRNNTATAKLIEYTNHLTKKHRDAVPRAAVEPLVQMLAPLAPHIAEELWLRLGNTT  890
            +   ++ NTA A+L+ + N   K ++  +       +VQ++AP+APH++EELW  L  + 
Sbjct  695  QVDQMKFNTAIAQLMVFVNAANKEDK--LFSDYAKGFVQLIAPFAPHLGEELWQALTASG  752

Query  891  -SLAHGPFPKADAAYLVDETVEYPVQVNGKVRGRVVVAADTDEETLKAAVLTDEKVQAFL  949
             S++  P P  D + LV++ VE  VQ++GKV++++VVA D   E L+   L++EKVQA +
Sbjct  753  ESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEI  812

Query  950  AGATPRKVIVVAGRLVNLVI  969
            AG    KVI V+ +LVN+VI
Sbjct  813  AGKDIIKVIAVPNKLVNIVI  832


 Score =  129 bits (474),  Expect = 7e-31, Method: Compositional matrix adjust.
 Identities = 73/148 (50%), Positives = 99/148 (67%), Gaps = 11/148 (7%)

Query  35   LERTWQENWARLGTFNVPNPVGSLAPPDGAAVPDDKLFVQDMFPYPSGEGLHVGHPLGYI  94
            +E  WQ  WA   TF+            G+  +  K++  DMFPYPSG GLHVGHP GY 
Sbjct  9    IEPKWQAFWADNHTFKT-----------GTDASKPKFYALDMFPYPSGAGLHVGHPEGYT  57

Query  95   ATDVYARYFRMVGRNVLHALGFDAFGLPAEQYAVQTGTHPRTRTEANVVNFRRQLGRLGF  154
            ATD+ +R+ R  G+NVLH++G DAFGLPAEQYA++TG +P   T  N+ NF+RQ+  LGF
Sbjct  58   ATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGF  117

Query  155  GHDSRRSFSTTDVDFYRWTQWIFLQIYN  182
            + D  R  +TTD ++Y+WTQWIF ++Y+
Sbjct  118  SYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1559) CCDC5180_0039 in NC_017522


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  508 bits (1918),  Expect = 5e-145, Method: Compositional matrix adjust.
 Identities = 349/740 (48%), Positives = 500/740 (68%), Gaps = 57/740 (7%)

Query  232  LVYRADSLVNWCPGLGTVLANEEVTADGRSDRGNFPVFRKRLRQWMMRITAYAdrllddl  291
            L Y A+  VNW   LGT +ANEEV +DG S+RG +PV RK +RQWM++ITAYA+RLL+DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  292  dvldWPEQVKTMQRNWIGRSTGAVALFSARAASDDGFEVDIEVFTTRPDTLFGATYLVLA  351
            + +DWPE +K MQRNWIG+STGA   F  + +     + D+ VFTTRPDTLFGATY VLA
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDT-----DKDFTVFTTRPDTLFGATYAVLA  262

Query  352  PEHDLVDELVAASWPAGVNPLWTYGGGTPGEaiaayrraiaaKSDLERQE-SGEKTGVFL  410
            PEH LVD + ++                 +EA+A Y+R  + KSDL R + + EKTGV  
Sbjct  263  PEHALVDAITTSD---------------QAEAVADYKRQASLKSDLARTDLAKEKTGVWT  307

Query  411  GSYAINPANGEPVPIFIADYVLAGYGTGAIMAVPGHDQRDWDFARAFGLPIVEVIAGGNI  470
            GSYAINP NG  +P+ IADYVLA+YGTGAIMAVP+HD+RDW+FA+ F L I+ V+ GGN+
Sbjct  308  GSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNV  367

Query  471  SESAYTGDGILVNSDYLNGMSVPAAKRAIVDRLESAGRGRARIEFKLRDWLFARQRYWGE  530
             E+A+T DG+ +NSD+L+G+  ++A   +V++LE+ G G   + ++LRDWLF+RQRYWGE
Sbjct  368  EEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGE  427

Query  531  PFPIVYDSDGRPHALDEAALPVELPDVPDYSPVLFdpddadsepsppLAKATEWVHVDLD  590
            P+PI+   DG + A+ E+ LP+ LP   D  P         +   +PLA+ T+W++V  +
Sbjct  428  PIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTDWLEVTRE  479

Query  591  LGDGLKPYSRDTNVMPQWAGSSWYELRYTDPHNSERFCAKENEAYWMGPRPAEHGPDDPG  650
              DG+K   R+TN MPQWAGSSWY LRY DPHN+E++   E    W+             
Sbjct  480  --DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWL-------------  523

Query  651  GVDLYVGGAEHAVLHLLYSRFWHKVLYDLGHVSSREPYRRLVNQGYIQAYAYTDARGSYV  710
             VD+YVGGAEHAVLHLLY+RFWHKVLYDLG V+++EP+++L NQG I + +Y D+RG+ V
Sbjct  524  PVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALV  583

Query  711  PAEQVIERGDRFVYPGPDGEVEVFQEFGKIGKSLKNSVSPDEICDAYGADTLRVYEMSMG  770
            ++++V  R++ F     + E+E  Q  +K++KSLKN V+PD++ + YGADTLRVYEM MG
Sbjct  584  ATDKVEKRDGSFFHVETGEELE--QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMG  641

Query  771  PLEASRPWATKDVVGAYRFLQRVWRLVVDEHTGETRVADGVELDIDTLRALHRTIVGVSE  830
            PL+AS +W+  ++ G+ +FL+RV RL+   +  E    ++  LD    +  + T+ +V+E
Sbjct  642  PLDASIAWSEEGLEGSRKFLDRVYRLITTKEITE---ENSGALD----KVYNETVKAVTE  694

Query  831  DFAALRNNTATAKLIEYTNHLTKKHRDAVPRAAVEPLVQMLAPLAPHIAEELWLRLGNTT  890
            +   ++ NTA A+L+ + N   K ++  +       +VQ++AP+APH++EELW  L  + 
Sbjct  695  QVDQMKFNTAIAQLMVFVNAANKEDK--LFSDYAKGFVQLIAPFAPHLGEELWQALTASG  752

Query  891  -SLAHGPFPKADAAYLVDETVEYPVQVNGKVRGRVVVAADTDEETLKAAVLTDEKVQAFL  949
             S++  P P  D + LV++ VE  VQ++GKV++++VVA D   E L+   L++EKVQA +
Sbjct  753  ESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEI  812

Query  950  AGATPRKVIVVAGRLVNLVI  969
            AG    KVI V+ +LVN+VI
Sbjct  813  AGKDIIKVIAVPNKLVNIVI  832


 Score =  129 bits (474),  Expect = 7e-31, Method: Compositional matrix adjust.
 Identities = 73/148 (50%), Positives = 99/148 (67%), Gaps = 11/148 (7%)

Query  35   LERTWQENWARLGTFNVPNPVGSLAPPDGAAVPDDKLFVQDMFPYPSGEGLHVGHPLGYI  94
            +E  WQ  WA   TF+            G+  +  K++  DMFPYPSG GLHVGHP GY 
Sbjct  9    IEPKWQAFWADNHTFKT-----------GTDASKPKFYALDMFPYPSGAGLHVGHPEGYT  57

Query  95   ATDVYARYFRMVGRNVLHALGFDAFGLPAEQYAVQTGTHPRTRTEANVVNFRRQLGRLGF  154
            ATD+ +R+ R  G+NVLH++G DAFGLPAEQYA++TG +P   T  N+ NF+RQ+  LGF
Sbjct  58   ATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGF  117

Query  155  GHDSRRSFSTTDVDFYRWTQWIFLQIYN  182
            + D  R  +TTD ++Y+WTQWIF ++Y+
Sbjct  118  SYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1560) leuS2 in NC_019670


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  508 bits (1917),  Expect = 5e-145, Method: Compositional matrix adjust.
 Identities = 365/874 (42%), Positives = 556/874 (64%), Gaps = 58/874 (6%)

Query  5    YQPREIEAAAQSFWDEQKSFEVSEQPGKETYYCLSMFPYPSGK-LHMGHVRNYTIGDVIS  63
            Y+   IE+  Q+FW ++ +F  + +++K  +Y L MFPYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMQGKNVLQPMGWDAFGMPAENAAMKNNVAPAKWTYENIAYMKSQLRSLGLAVDWSR  123
            R++R QG NVL+PMGWDAFG+PAE+ AM     PA  T ENIA  K Q+ +LG++ DW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVTTCKPDYYRWEQWLFTRLFEKGVIYKKSGTVNWDPVDQTVLANEQVI-DGRGWRSGAL  182
            EV T  P+YY+W QW+FT+L+EKG+ Y     VNW     T +ANE+V+ DG + R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  IEKREIPMYYFKITAYADELLESLDELTGWPEQVKTMQRNWIGKSRGMEVQFPYNVDSIG  242
            + ++ +    +KITAYA+ LLE L+E+ +WPE +K MQRNWIGKS G +V F  +V   +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTF--KVKDTD  240

Query  243  ETGALKVFTTRPDTLMGATYVAVAAEHHLATLAAQNNPELQAFIAECKGGSVAEADVA--  300
                + VFTTRPDTL GATY  +A+EH L  + A   ++    +A+ K  +   +D+A  
Sbjct  241  K--DFTVFTTRPDTLFGATYAVLAPEHAL--VDAITTSDQAEAVADYKRQASLKSDLART  296

Query  301  --TQEKKGLPTGLFVEHPLTGEKLPVWVANYVLMHYGDGAVMAVPAHDERDFEFAHKYNL  358
              ++EK G+ TG +  +P+ G  +PVW+A+YVL  YG GA+MAVPAHDERD EFA ++NL
Sbjct  297  DLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNL  356

Query  359  PVKSVVRTSSGDTNPAPWQDAYGEHGTLINSGEFDGLDFAGAFDAIEVALIKKELGASRT  418
             + +V+  ++ +      + A+ E+G  INS+ +DGLD A+A+  +   L    +G    
Sbjct  357  DIIPVLEGGNVE------EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENV  410

Query  419  QFRLRDWGISRQRYWGCPIPIIHCTTCGDVPVPEDQlpvvlpedvvpdGAG---SPLARM  475
             +RLRDW +SRQRYWG PIPIIH       +VPE +LP+VLP       +G   SPLA +
Sbjct  411  TYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANV  470

Query  476  PEFYECTCPKCGAPAKRETDTMDTFVESSWYYARYASPHFEGGLVEKSAADHWLPVDQYI  535
             +  E T    G  ++RET+TM     SSWYY RY  PH    L +     +WLPVD Y+
Sbjct  471  TDWLEVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYV  529

Query  536  GGIEHAILHLLYARFFHKLMRDEGLVSSNEPFKNLLTQGMVIAETYYRREANGAYTWFNP  595
            GG EHA+LHLLYARF HK++ D G+V+++EPF++L+ QGM+++ +Y  R++ GA   + +
Sbjct  530  GGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY--RDSRGA---LVA  584

Query  596  ADVELERDSKAKVISAKLKADGLPVEIGGTEKMAKSKNNGVDPQSMIDQFGADTCRLFMM  655
            +D    RD+    + +   ++ L     +  KM+KS +N V+P+ +++Q+GADT R++ M
Sbjct  585  TDKVEKRDGSFFHVET---GEELE---QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEM  638

Query  656  FASPPDMSAEWSDSGVEGSHRFLKRVWRLAQA-HVTQGLPGKLDVASLNDEQKAVRRSIH  714
            F +P D S  WS+ G+EGS++FL RV RL  + ++T+  +G LD            +  +
Sbjct  639  FMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALD------------KVYN  686

Query  715  LAIKQASQDVGQNHKFNTAIAQVMTLMNVLEKAAQG-TEQDRALVQEGLETVTLLLAPIT  773
             ++K  +++V+Q  KFNTAIAQ+M ++N  +K  +  ++  +++VQ        L+AP++
Sbjct  687  ETVKAVTEQVDQM-KFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQ--------LIAPFA  737

Query  774  PHISHELWHRLGHADPVID-AGWPVVDDSALVQDSLQLVIQVNGKLRGQIEMPasasree  832
            PH+++ELW+ L  ++  I    WP  D+S LV++ +++V+Q++GK+++++ ++   SREE
Sbjct  738  PHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREE  797

Query  833  veaaaranenvLRFVDGLTIRKVIVVPGKLVNIV  866
            ++  A ANE+V   + G  I KVI VP KLVNIV
Sbjct  798  LQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIV  831

1561) swp_3914 in NC_011566


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  508 bits (1918),  Expect = 5e-145, Method: Compositional matrix adjust.
 Identities = 358/866 (42%), Positives = 548/866 (64%), Gaps = 47/866 (5%)

Query  11   YTPSEIEAKVQQHWKDEKTFEVTEDANKEKFYCLSMFPYPSGR-LHMGHVRNYTIGDVVA  69
            Y  + IE+K Q  W D+ TF    DA+K KFY L MFPYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  70   RYQRLQGKNVLQPIGWDSFGLPAENAAIKNNTAPAPWTYENIDYMKNQLKMLGFGYDWSR  129
            R++R QG NVL+P+GWD+FGLPAE+ A+     PA  T ENI   K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  130  EIATCTPEYYRWEQWFFTKLYEKGLVYKKTANVNWCPNDETVLANEQVI-DGCCWRCDTT  188
            E+ T  P+YY+W QW+FTKLYEKGL Y     VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  189  VEQKEIPQWFIKITEYADELLKDIDQLDEWPEQVKTMQRNWIGRSEGIEMTFQVADSDQS  248
            V +K + QW +KIT YA+ LL D++++D WPE +K MQRNWIG+S G ++TF+V D+D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  249  FDIYTTRPDTVMGVTY--VaiaaahplakqaaannpalaEFIEECNNADtteaamaamek  306
            F ++TTRPDT+ G TY  +A   A   A  ++ +  A+A++  + +       +  A EK
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEK  302

Query  307  kGVATGLNAIHPLTGKEVPIWVGNFVLMNYGTGAVMSVPAHDQRDYEFAKKYGLTIEGVV  366
             GV TG  AI+P+ GKE+P+W++++VL +YGTGA+M+VPAHD+RD EFAK++ L I  V+
Sbjct  303  TGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL  362

Query  367  KPADSDLDISEEAYTEKGVLFNSGEFDGLDFQAAFDAIDAKLSAEGKGKRQVNFRLRDWG  426
              +    ++ E A+TE G+ +NS+ +DGLD  +A+  +   L AEG G+ +V +RLRDW 
Sbjct  363  EGG----NVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWL  418

Query  427  VSRQRYWGAPIPMVTLADGTVMPTPEEQLPVILP--EDVVMDGI-QSPIKADKEWAKTTI  483
             SRQRYWG PIP++   DGT  + PE +LP++LP   D+   G  +SP+    +W   T 
Sbjct  419  FSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTR  478

Query  484  -NGQEAFRETDTFDTFMESSWYYARYCSPDADEML-DPAKANYWLPVDQYIGGIEHACMH  541
             +G  + RET+T      SSWYY RY  P+  E L D    + WLPVD Y+GG EHA +H
Sbjct  479  EDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLH  538

Query  542  LLYFRFFHKLLRDTGLVNSDEPAKRLLTQGMVLADAYYYNNEKGARVWVAPSDVTVLETD  601
            LLY RF HK+L D G+V + EP ++L+ QGM+L+ +Y     +++R     + +   +  
Sbjct  539  LLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSR-----GALVATDKV  588

Query  602  DKGRTVKAVDSEGNELVYTGMSKMSKSKNNGIDPQEMVDKYGADTVRLFMMFAAPPELTL  661
            +K R     + E  E +  + +KMSKS +N ++P+++V++YGADT+R++ MF +P + ++
Sbjct  589  EK-RDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASI  647

Query  662  EWQESSVEGAHRFIKRLWK-TAHDHIAAGPTVALDIKSLNAGQKELRRELHKTIAKVGDD  720
             W E ++EG+++F+ R+ +  +  +I+   + ALD            +  + T+  V ++
Sbjct  648  AWSEEGLEGSRKFLDRVYRLITTKEITEENSGALD------------KVYNETVKAVTEQ  695

Query  721  IERRQMFNTAIASVMELMNRLQKAPTDSEQDRALMQEALSAVTRLLYPIIPHTSFSLWNE  780
            +++ + FNTAIA +M ++N        ++++  L  +   +  +L+ P+ PH +  LW+ 
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  781  LGNTG-AIEDVLWPEVDESALVEDSKLIIVQVNGKLRAKVTvaadaskeaveaagmaeeg  839
            L  +G +I  V WP  DES LVE+   I+VQ++GK++AK+ VA D S+E ++  ++A+E 
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  840  vIKHTEGKTVRKVIYVPGKLLNIVAN  865
            V  +  GK + KVI VP KL+NIV +
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVIK  833

1562) leuS in NC_009434


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  508 bits (1918),  Expect = 5e-145, Method: Compositional matrix adjust.
 Identities = 362/884 (41%), Positives = 550/884 (63%), Gaps = 74/884 (8%)

Query  43   YQPREIEAAAQSHWDSQKSFEVSEQPGKDTFYCLSMFPYPSGK-LHMGHVRNYTIGDVIA  101
            Y+   IE+  Q+ W  + +F  + +++K  FY L MFPYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  102  RYQRMQGKNVLQPMGWDAFGMPAENAAMKNQVAPAKWTYENIAYMKAQLKSLGLAIDWSR  161
            R++R QG NVL+PMGWDAFG+PAE+ AM     PA  T ENIA  K Q+++LG++ DW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  162  EVTTCKPDYYRWEQWLFTRLFEKGVIYRKNGTVNWDPVDQTVLANEQVI-DGRGWRSGAL  220
            EV T  P+YY+W QW+FT+L+EKG+ Y  +  VNW     T +ANE+V+ DG + R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  221  IEKREIPMYYFKITAYAdellesldeldGWPEQVKTMQRNWIGKSRGMEISFPYDVASIG  280
            + ++ +    +KITAYA E L    E  +WPE +K MQRNWIGKS G +++F   V   +
Sbjct  184  VVRKPMRQWMLKITAYA-ERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTF--KVKDTD  240

Query  281  NEGVMKVFTTRPDTLMGATYVAVAAEHPLATLAAQHNPELQAFIDECKRGGVAEADIA--  338
            ++    VFTTRPDTL GATY  +A+EH+L  + A   ++    + + KR +   +D+A  
Sbjct  241  KD--FTVFTTRPDTLFGATYAVLAPEHAL--VDAITTSDQAEAVADYKRQASLKSDLART  296

Query  339  --TQEKKGLATSLRVQHPLTGELLPVWVANYVLMNYGEGAVMAVPAHDERDFEFASKYGL  396
              ++EK G+ T+    +P+ G  +PVW+A+YVL +YG GA+MAVPAHDERD EFA ++ L
Sbjct  297  DLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNL  356

Query  397  PIKPVVRTSAGDETPAPWQDAYGEHGQLINSGIYDGLDFEGAFDAIEVALQKKGLGQART  456
             I PV+  +  +E+      A+ E+G  INS++ DGLD  +A+  +   L+  G+G+   
Sbjct  357  DIIPVLEGGNVEEA------AFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENV  410

Query  457  QFRLRDWGISRQRYWGCPIPIIHCDSCGDVPVPEDQlpvvlpedvvpdGAG---SPLARM  513
             +RLRDW +SRQRYWG PIPIIH +     +VPE +LP+VLP       +G   SPLA +
Sbjct  411  TYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANV  470

Query  514  PEFYECTCPKCGAPAKRETDTMDTFVESSWYFARYASPNYDKGMVDPQAANHWLPVDQYI  573
             +  E T    G  ++RET+TM     SSWY+ RY  P+    + D +  ++WLPVD Y+
Sbjct  471  TDWLEVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYV  529

Query  574  GGIEHAILHLLYARFFHKLMRDEGLVSSNEPFKNLLTQGMVVAETYYRTLENGGKDWFNP  633
            GG EHA+LHLLYARF HK++ D G+V+++EPF++L+ QGM+++ +Y              
Sbjct  530  GGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY--------------  575

Query  634  ADVEVERDAKAKVIGARL--KTDG--LPVEIG-----GTEKMSKSKNNGVDPQAMIDAYG  684
                  RD+++ ++++    K DG  + VE G     +  KMSKS +N V+P+ +++ YG
Sbjct  576  ------RDSRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYG  629

Query  685  ADTCRLFMMFASPPDMSLEWSDSGVEGASRFLRRVWRLAHA-HVSAGLPGALDVAALNDE  743
            ADT R++ MF +P D S+ WS+ G+EG+ +FL RV RL  + +++   +GALD       
Sbjct  630  ADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALD-------  682

Query  744  QKAVRRAIHLAIKQASTDVGQHHKFNTAIAQVMTLMNVLEKAPTAGEQDRALLQEGLETV  803
                 +  + ++K  + +V ++ KFNTAIAQ+M ++N       A++++  L+ +     
Sbjct  683  -----KVYNETVKAVTEQV-DQMKFNTAIAQLMVFVN-------AANKEDKLFSDYAKGF  729

Query  804  ALLLAPITPHICHELWQQLGKPGAIID-AQWPKVDEAALVQDSLTLVVQVNGKLRGQIEV  862
              L+AP++PH+ +ELWQ L  +G  I    WP  DE+ LV++ + +VVQ++GK+++++ V
Sbjct  730  VQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVV  789

Query  863  PASASREEVETAARGNENVLRFTEGLTIRKVIVVPGKLVNIVAN  906
            +   SREE++  A +NE+V     G  I KVI VP KLVNIV +
Sbjct  790  AKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

1563) Sfum_2084 in NC_008554


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  508 bits (1918),  Expect = 5e-145, Method: Compositional matrix adjust.
 Identities = 343/846 (41%), Positives = 522/846 (62%), Gaps = 74/846 (8%)

Query  5    YAPKRIEKKWQEHWEREKLFEVSEIPGREKFYLLEMFPYPSGR-IHMGHVRNYSIGDVVA  63
            Y    IE KWQ  W  +  F  +  +++ KFY L+MFPYPSG  +H+GH   Y+  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RFLRMRGYNVLHPMGWDAFGMPAENAAIKAKTHPARWTYENIAYMRSQLKQLGFSYDWSR  123
            RF R +G NVLHPMGWDAFG+PAE+ A+ +  +PA  T ENIA  + Q++ LGFSYDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EFATCDVSYYRWEQLFFLKMYEKGLAYKRSAYVNWCGTCLTVLANEQV-EGGACWRCDQP  182
            E  T D +YY+W Q +F K+YEKGLAY     VNW     T +ANE+V  +G+  R + P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VVQKEMEQWFFKITDYVEELLDYTHRLPGWPERVLTMQQNWIGKSLGSKLLFPLASGDGS  242
            VV+K M QW +KIT Y E LL+  + + +WPE +  MQ+NWIGKS G+++ F +   D  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  ITVFTTRADTLFGATFMSLAPEHPLVEGLCRGNPQESEVLRFVQAAKQAKRNDREAELLE  302
            +TVFTTR+DTLFGAT+  LAPEH+LV+++  ++  E+ V  + + A       R     E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEA-VADYKRQASLKSDLARTDLAKE  301

Query  303  KEGVFTGSCCINPVTGAKMPIYVANFVVMEYGTGAVMAVPAHDQRDFEFARKYGLPVKVV  362
            K GV TGS  INPV G  MP+ +A++V+  YGTGA+MAVPAHD+RD EFA+++ L +  V
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  363  IKPadaaaapaaqelsaaFEDDGVLVDSGAYSGMASAEARTAITADLAGKGLGEQTVQYR  422
            +          ++   AAF +DG+ ++S+   G+  A A + +   L + G+G++ V YR
Sbjct  362  LEG--------GNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYR  413

Query  423  LRDWGISRQRYWGAPIPIVYCDKCGTVPVPEKDLPVVLPTDVALLPNGA--SPLPAHAPF  480
            LRDW +SRQRYWG PIPI+  +   + +VPE +LP+VLP    + P+G+  SPL+  +  
Sbjct  414  LRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDW  473

Query  481  LNTDCPRCGGPARRETDTMDTFVESSWYFARFACARYDQGPLDLPKVKYWMPVDQYIGGI  540
            L+      G  +RRET+TM     SSWY+ R+  ++  +   D   +K W+PVD Y+GG 
Sbjct  474  LEV-TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGA  532

Query  541  EHAVLHLLYSRFFVKVLRDMGALEVDEPFRNLLTQGMVI-------------------KD  581
            EHAVLHLLY+RF  KVL D+G +   EPF++L+ QGM++                   +D
Sbjct  533  EHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRD  592

Query  582  G---------------AKMSKSKGNVVDPDDMIKAYGADTVRLFCLFASPPEKDLEWSDQ  626
            G               AKMSKS  NVV+PDD++  YGADT+R++ +F +P +  + WS++
Sbjct  593  GSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEE  652

Query  627  GVEGSFRFLSRIWRLVSDNLDALRSAPRHNGGGALPEPLEALHRKTHQTIKKVTEDIRDR  686
            G+EGS +FL R+ RL++      +    +N+G        AL++  ++T+K VTE++ D+
Sbjct  653  GLEGSRKFLDRVYRLITT-----KEITEENSG--------ALDKVYNETVKAVTEQV-DQ  698

Query  687  FHFNTAIAAIMELVNQIYQVVEGGSRAGNIWPVVKEAVEALILLVSPMAPHIAEEIWHEL  746
              FNTAIA +M +VN       ++++ +++     +   +++ L++P APH++EE+W+ L
Sbjct  699  MKFNTAIAQLMVFVN-------AANKEDKL---FSDYAKGFVQLIAPFAPHLGEELWQAL  748

Query  747  -GHTRSVLLEPWPEWSGKALQAEEVMLVVQVNGRLRSRITVPSDATPEQMEAAALADSRV  805
             +   S+   PWP      L  ++V +VVQ++G++++++ V+ D + E+++  ALA+ +V
Sbjct  749  TASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKV  808

Query  806  QEFIAG  811
            Q  IAG
Sbjct  809  QAEIAG  814

1564) APP7_0931 in NC_010939


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  507 bits (1913),  Expect = 1e-144, Method: Compositional matrix adjust.
 Identities = 340/805 (43%), Positives = 525/805 (66%), Gaps = 46/805 (5%)

Query  5    YNPSAIEPKVQQFWAENKVFKAVKDVTKEKYYCLSMLPYPSGK-LHMGHVRNYTIGDVVS  63
            Y+ +AIEPK Q FWA+N  FK+  D +K K+Y L M+PYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMIGKNVLQPMGWDAFGLPAEGAAVKNNTAPAKWTYENIEYMKGQLKMLGFSYDWDR  123
            R++R  G NVL+PMGWDAFGLPAE  A+     PA  T ENI   K Q++ LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVTTCRQEYYKWEQWFFTELYKKGLVYKKTSTVNWCPNDATVLANEQV-HEGCCWRCDTP  182
            EV T   +YYKW QW+FT LY KGL Y     VNW  + +T +ANE+V  +G   R + P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VEQREIPQWFIKITDYAEELLTHLDNLPQWPDQVKTMQRNWIGRSEGVEITFKIAGSNAE  242
            V ++ + QW +KIT YAE LL +L+++ +WP+ +K MQRNWIG+S G ++TFK+ +++ +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LPVYTTRPDTFFGVSY--VaiaaahplaemaaENNPALAEFIREAK-NTKVAEAELATME  299
            + V+TTRPDT+FG +Y  +A   A   A  ++++  A+A++ R+A  ++ +A ++LA  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGMATGLFAIHPLTGKEVPVWVANFVLMHYGTGAVMAVPAHDERDFEFAQKYGLQINQV  359
            K G+ TG +AI+P+ GKE+PVW+A++VL  YGTGA+MAVPAHDERD EFA+++ L+I   
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDI---  358

Query  360  IQPLDGSEWDFSKAAYTEHGKLINSAEFDDLNFEQAFNAIADKLESMKVGKRQVNFRLRD  419
            I  L+G+  +   AA+TE+G  INS  +D+L+   A+  + + LE+  VG+ +V +RLRD
Sbjct  359  IPVLEGG--NVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMMTTEDGEVVTVPMQDLPVILP--EDVVMNGV-QSPIKADPEWAKT  476
            W  SRQRYWG PIP++  EDG   +VP  +LP++LP   D+  +G  +SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  TY-NGKPALKETDTFDTFMESSWYYARYTCPQYHEGMLDSDEANYWLPVDQYIGGIEHAT  535
            T  +G  + +ET+T      SSWYY RY  P+  E + D +  + WLPVD Y+GG EHA 
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLLYFRFFHKLLRDAGILNSDEPATKLLCQGMVLADAFYYTSPTNERIWVSPTQVTLER  595
            +HLLY RF HK+L D G++ + EP  KL+ QGM+L+ ++      + R     + V+ ++
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSR----GALVATDK  587

Query  596  DEKGRIIKATDPEGRELVHSGMTKMSKSKNNGIDPQEMVEKYGADTVRLFMMFASPAEMT  655
             EK R     + E  E ++ + +KMSKS +N ++P+++VE+YGADT+R++ MF +P + +
Sbjct  588  VEK-RDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  656  LEWQESGVEGAKRFLGRVWNLVYEYSQNPATAALDVAALSKAQKELRRDVHKTIAKVSDD  715
            + W E G+EG+++FL+RV  L+         +  + +AL K  +E       T+  V+++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLI----TTKEITEENSGALDKVYNE-------TVKAVTEQ  695

Query  716  IGRRQTFNTAIAAIMELMNKLTKAPLENEQDKAVMAEALSAVVRMLYPITPHICFELWQA  775
            +++ + FNTAIA +M ++N         +++  + ++   + V+++ P++PH+  ELWQA
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  776  L-GNNDTIDFAPWVVADESAMVEDE  799
            L ++ ++I + PW   DES +VE++
Sbjct  748  LTASGESISYVPWPSYDESKLVEND  772

1565) Kole_0173 in NC_012785


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  507 bits (1913),  Expect = 1e-144, Method: Compositional matrix adjust.
 Identities = 331/814 (41%), Positives = 514/814 (64%), Gaps = 44/814 (5%)

Query  20   PFKVDLKNAKKPFYNLMMFPYPSASGLHIGNMYSFIGSDVYGRYKKLQGYDVFEPIGFDA  79
             FK +   +K  FY L MFPYPS++GLH+G+  ++ ++D+ +R+K+ QG +V++P+G DA
Sbjct  22   TFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSRFKRAQGHNVLHPMGWDA  81

Query  80   FGIHSENYALKVGEHPAKLTPKSIKYFRDEQLKKIGNIYDWSSEVNTSSPEYYKWTQWIF  139
            FG+ +E+YA+  G++PA +T+ +I  F+  Q++ +G  YDW  EVNT+ P+YYKWTQWIF
Sbjct  82   FGLPAEQYAMDTGNDPAEFTAENIANFK-RQINALGFSYDWDREVNTTDPNYYKWTQWIF  140

Query  140  LQLYKAGLAEKKNSEVNWCPSCKTVLADEQVI-DGKCERCSTEITKREMSQWFFKITKYA  198
             +LY  GLA   +  VNW     T +A+E+V+ DG  ER +  + ++ M QW +KIT YA
Sbjct  141  TKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYA  200

Query  199  DRLLENLEKLDWTETTKNIQRSWIGRSEGAKIRFPVENSDIEIEVFTTRPDTIYGVTYLT  258
            +RLLE+LE +DW E+ K++QR+WIG+S GA++ F V ++D ++ VFTTRPDT++G TY  
Sbjct  201  ERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAV  260

Query  259  LAPEHKLVKKLIKEDKFSQFEEFLESVKKMDVATRTSKTRPKTGMFTGSYAIHPLTGERI  318
            LAPEH LV  +   D+     ++          +RT  ++ KTG+ TGSYAI+P+ G  +
Sbjct  261  LAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAINPVNGKEM  320

Query  319  PIWVGDYVLVEYGTGAVMAVPAHDERDYAFAKKYGLEIKQVIE-CDPEDLPYTEKGIMIN  377
            P+W++DYVL  YGTGA+MAVPAHDERD  FAK++ L+I  V+E  + E+ ++TE G+ IN
Sbjct  321  PVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEAAFTEDGLHIN  380

Query  378  SGPYTGWKSEDFIANID---SVHEKIESAVTYHLHDWCVSRQRYWGPPIPIIYCDKCGIv  434
            S+   G      IA++      +   +  VTY+L+DW  SRQRYWG PIPII  +     
Sbjct  381  SDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTST  440

Query  435  pvpeedlpvllpetddYIPDGSGKSPLARNEEFVNTTCPKCGGPAKRETDVSDNFLDSAW  494
            +VPE +LP++LP T D  P G+G SPLA   + ++ T    G  ++RET+   +  +S+W
Sbjct  441  AVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED-GVKGRRETNTMPQWAGSSW  499

Query  495  YFLRYISPHDQDRPFDPELAKKWLPVDMYIGGNEHANLHLMYARFITMALHDLGILHFEE  554
            Y+LRYI PH+ ++  D EL K+WLPVD+Y+GG EHA LHL+YARF    L DLG++   E
Sbjct  500  YYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKE  559

Query  555  PFKSFRGHGLII-------------------KDG---------------EKMSKSKGNIV  580
            PF+ +  +G+I+                   +DG                KMSKS  N+V
Sbjct  560  PFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVV  619

Query  581  NPNDYFDTHGVDALRTYLMFMGSFLEGGDFRDSGMDAIKRFLNRVWEVANKPE--GESSL  638
            NP+D  +  G D+LR Y MFMG++  +    + G+++ ++FL+RV  +    E   E+S 
Sbjct  620  NPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITEENSG  679

Query  639  QLKIKMAETIKKVEYSIENIKYNTAIAAIMEFINEAVKEERIERQLVVDLAKLLAPFAPF  698
             L     ET+K V   ++++K+NTAIA +M F+N A KE+++  +   ++ +L+APFAP 
Sbjct  680  ALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPH  739

Query  699  ICEEI-HEMKGGKGTILNAGWPTGYDKYLSMADVEIPVQINGKMRGKVKIHQKASEDEVI  757
            + EE+ + + ++  +I    WP+  +  L   DVEI VQI+GK+++K+ + +  S +E+ 
Sbjct  740  LGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQ  799

Query  758  EKIKGDERLAHYLNKGEIRKVIYVQDKIINIIVK  791
            E   ++E++   +   +I KVI V +K++NI++K
Sbjct  800  EVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

1566) leuS in NC_015740


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  507 bits (1914),  Expect = 1e-144, Method: Compositional matrix adjust.
 Identities = 362/884 (41%), Positives = 550/884 (63%), Gaps = 74/884 (8%)

Query  5    YQPREIEAAAQSHWDSQKSFEVSEQPGKDTFYCLSMFPYPSGK-LHMGHVRNYTIGDVIA  63
            Y+   IE+  Q+ W  + +F  + +++K  FY L MFPYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMQGKNVLQPMGWDAFGMPAENAAMKNQVAPAKWTYENIAYMKAQLKSLGLAIDWSR  123
            R++R QG NVL+PMGWDAFG+PAE+ AM     PA  T ENIA  K Q+++LG++ DW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVTTCKPDYYRWEQWLFTRLFEKGVIYRKNGTVNWDPVDQTVLANEQVI-DGRGWRSGAL  182
            EV T  P+YY+W QW+FT+L+EKG+ Y  +  VNW     T +ANE+V+ DG + R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  IEKREIPMYYFKITAYAdellesldeldGWPEQVKTMQRNWIGKSRGMEISFPYDVASIG  242
            + ++ +    +KITAYA E L    E  +WPE +K MQRNWIGKS G +++F   V   +
Sbjct  184  VVRKPMRQWMLKITAYA-ERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTF--KVKDTD  240

Query  243  NEGVMKVFTTRPDTLMGATYVAVAAEHPLATLAAQHNPELQAFIDECKRGGVAEADIA--  300
            ++    VFTTRPDTL GATY  +A+EH+L  + A   ++    + + KR +   +D+A  
Sbjct  241  KD--FTVFTTRPDTLFGATYAVLAPEHAL--VDAITTSDQAEAVADYKRQASLKSDLART  296

Query  301  --TQEKKGLATSLRVQHPLTGELLPVWVANYVLMNYGEGAVMAVPAHDERDFEFASKYGL  358
              ++EK G+ T+    +P+ G  +PVW+A+YVL +YG GA+MAVPAHDERD EFA ++ L
Sbjct  297  DLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNL  356

Query  359  PIKPVVRTSAGDETPAPWQDAYGEHGQLINSGIYDGLDFEGAFDAIEVALQKKGLGQART  418
             I PV+  +  +E+      A+ E+G  INS++ DGLD  +A+  +   L+  G+G+   
Sbjct  357  DIIPVLEGGNVEEA------AFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENV  410

Query  419  QFRLRDWGISRQRYWGCPIPIIHCDSCGDVPVPEDQlpvvlpedvvpdGAG---SPLARM  475
             +RLRDW +SRQRYWG PIPIIH +     +VPE +LP+VLP       +G   SPLA +
Sbjct  411  TYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANV  470

Query  476  PEFYECTCPKCGAPAKRETDTMDTFVESSWYFARYASPNYDKGMVDPQAANHWLPVDQYI  535
             +  E T    G  ++RET+TM     SSWY+ RY  P+    + D +  ++WLPVD Y+
Sbjct  471  TDWLEVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYV  529

Query  536  GGIEHAILHLLYARFFHKLMRDEGLVSSNEPFKNLLTQGMVVAETYYRTLENGGKDWFNP  595
            GG EHA+LHLLYARF HK++ D G+V+++EPF++L+ QGM+++ +Y              
Sbjct  530  GGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY--------------  575

Query  596  ADVEVERDAKAKVIGARL--KTDG--LPVEIG-----GTEKMSKSKNNGVDPQAMIDAYG  646
                  RD+++ ++++    K DG  + VE G     +  KMSKS +N V+P+ +++ YG
Sbjct  576  ------RDSRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYG  629

Query  647  ADTCRLFMMFASPPDMSLEWSDSGVEGASRFLRRVWRLAHA-HVSAGLPGALDVAALNDE  705
            ADT R++ MF +P D S+ WS+ G+EG+ +FL RV RL  + +++   +GALD       
Sbjct  630  ADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALD-------  682

Query  706  QKAVRRAIHLAIKQASTDVGQHHKFNTAIAQVMTLMNVLEKAPTAGEQDRALLQEGLETV  765
                 +  + ++K  + +V ++ KFNTAIAQ+M ++N       A++++  L+ +     
Sbjct  683  -----KVYNETVKAVTEQV-DQMKFNTAIAQLMVFVN-------AANKEDKLFSDYAKGF  729

Query  766  ALLLAPITPHICHELWQQLGKPGAIID-AQWPKVDEAALVQDSLTLVVQVNGKLRGQIEV  824
              L+AP++PH+ +ELWQ L  +G  I    WP  DE+ LV++ + +VVQ++GK+++++ V
Sbjct  730  VQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVV  789

Query  825  PASASREEVETAARGNENVLRFTEGLTIRKVIVVPGKLVNIVAN  868
            +   SREE++  A +NE+V     G  I KVI VP KLVNIV +
Sbjct  790  AKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

1567) leuS in NC_005072


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  507 bits (1912),  Expect = 2e-144, Method: Compositional matrix adjust.
 Identities = 352/835 (43%), Positives = 538/835 (65%), Gaps = 39/835 (4%)

Query  13   NLYKPSDIEGKWQKIWEDDNLYNTDEQASNKEKFYALSMFPYPSG-NLHMGHVRNYVITD  71
             +Y  + IE KWQ +W D++ ++T+ +AS K KFYAL MFPYPSG  LH+GH   Y  TD
Sbjct  2    TFYDHTAIEPKWQAFWADNHTFKTGTDAS-KPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  72   LIARFQRFQGKVVLHPMGWDAFGLPAENAAIERGINPDKWTKQNIAHMKSQLKLLGLSVD  131
            +++RF+R QG  VLHPMGWDAFGLPAE+ A++ G +P   T +NIA+ K Q++ LG+S D
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  132  WDREFATCDENYYVWTQFLFLELHKAGLVYQKESEVNWDPIDNTVLANEQVDSEGKSWRS  191
            WDRE  T D NYY WTQ +F  L   GL Y+ E  VNW     T +ANE+V ++G S R+
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  192  GAIVEKKLLTQWFLKITDYAEELLQDLEKLNEWPERVKIMQENWIGKSIGTninfkikef  251
            G  V +K + QW LKIT YAE LL+DLE + +WPE +K MQ NWIGKS G+N+ FK+K+ 
Sbjct  181  GYPVVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDT  239

Query  252  kkekiQVFTTRPDTLFGVTYLAISVNHPLIKKISDNKILSKLEN------LKIYLQESKD  305
             K+   VFTTRPDTLFG TY  ++ +H+L+  I+ +     + +      LK  L    D
Sbjct  240  DKDFT-VFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDL-ARTD  297

Query  306  KDQKKIGIPTNLIAINPINSKEIPILIASYVLDEYGTGAVMGVPAHDERDFEFAKINSID  365
              + K G+ T   AINP+N+KE+P+ IA YVL  YGTGA+M+VPAHDERD EFAK  ++D
Sbjct  298  LAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLD  357

Query  366  IKQVIIKEKDKITSQLTNAFTDNGFLINSNNFDGLNNSDAKKHISEHGERNGWAENKIQF  425
            I  V+  E +++      AFT++G+ INS+ +DGL+++ A   + E  E +G +++++ +
Sbjct  358  IIPVL--EGGNVEE---AAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTY  412

Query  426  RLRDWLISRQRYWGCPIPIIKCTNCGSVPVNKKDIPVRLP--NEIKISSNKINSLGSNQS  483
            RLRDWL+SRQRYWG PIPII   +  S +V   ++P+ LP  ++I+ S+   ++L++   
Sbjct  413  RLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTD  472

Query  484  WINTTCPKCGNLASRETDTMDTFMCSSWYFLRYPSSKSLTKPFEKEKINKWLPVDQYVGG  543
            W++ T    G  + RET+TM     SSWY+LRY  + +  K  + E +++WLPVD YVGG
Sbjct  473  WLEVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGG  531

Query  544  VEHAILHLLYARFLTKALRDNNLFDIDEPFKRLLTQGMVQSAAYKNSITGKYISPTDIKD  603
             EHA+LHLLYARF  K L D  +    EPF++L+ QGM+ +++Y++S  +  + +TD  +
Sbjct  532  AEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGA--LVATDKVE  589

Query  604  ITNPK--DPKDNSKLEVLFEKMSKSKYNGIDPESVIKKYGADTARMFILFKAPPEKDLEW  661
              +    +      LE    KMSKS  N ++P+ V+ +YGADT R++ +F +P +  + W
Sbjct  590  KRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAW  649

Query  662  GDSDVEGQYRFLCRIWKLFLDYSNNDITHEADklkkenessllksINIAIKEISNDIKNN  721
            ++ ++EG  +FL R+ +L+   + ++IT+E         ++L K  N ++K +++++ + 
Sbjct  650  SEEGLEGSRKFLDRVYRLI---TTKEITEENS-------GALDKVYNETVKAVTEQVDQM  699

Query  722  QFNTAISELMKFYNSISSNLNYVNKDLRRESLMKFCILLAPFAPHISDEIWH-LIGNSKS  780
            +FNTAI++LM F N+ +      +  L  +    F  L+APFAPH+++E+W+ L +++ S
Sbjct  700  KFNTAIAQLMVFVNAANK-----EDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGES  754

Query  781  VHLEKWPVFDEDALKENSFELVIQINGKVRDKINVEINISDDEIKEKTLIRPNVK  835
            +    WP +DE  L EN  E+V+QI+GKV+ K+ V  ++S +E++E +L   +V+
Sbjct  755  ISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQ  809

1568) OEM_00480 in NC_021715


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  506 bits (1910),  Expect = 2e-144, Method: Compositional matrix adjust.
 Identities = 348/738 (48%), Positives = 496/738 (68%), Gaps = 55/738 (7%)

Query  232  LVYRADSMVNWCPGLGTVLANEEVTADGRSDRGNFPVFRKRLRQWMMRITAYSdrllddl  291
            L Y A+  VNW   LGT +ANEEV +DG S+RG +PV RK +RQWM++ITAY++RLL+DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  292  elldWPEPVKAMQRNWIGRSTGAKALFAATRADGEAVDIEVFTTRPDTLFGATYLVLAPE  351
            E +DWPE++K MQRNWIG+STGA+  F    +D    D+ VFTTRPDTLFGATY VLAPE
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDK---DFTVFTTRPDTLFGATYAVLAPE  264

Query  352  HDLVDELVAAAWPDGTDPRWTYRAATPGEAVAAYRKAIASKSDLERQE-SKAKTGVFLGS  410
            H LVD + ++                 +EAVA Y++  + KSDL R + +K KTGV  GS
Sbjct  265  HALVDAITTSD---------------QAEAVADYKRQASLKSDLARTDLAKEKTGVWTGS  309

Query  411  YATNPTNGKPVPIFIADYVLAGYGTGAIMAVPGHDQRDWDFAHEFGLPIVEVIAGGDISE  470
            YA NP NGK +P+ IADYVLA+YGTGAIMAVP+HD+RDW+FA +F L I+ V+ GG++ E
Sbjct  310  YAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEE  369

Query  471  AAYAGDGVLVNSGYLDGLDVAAAKEKITARLESEGRGRARIEFKLRDWLFARQRYWGEPF  530
            AA++ DG+ +NS++LDGLD A+A  K+  +LE+EG G   + ++LRDWLF+RQRYWGEP+
Sbjct  370  AAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPI  429

Query  531  PIVYDSDGRAHALDEAALPVELPDVPDYSPVLFdpddadsepsppLAKATEWVHVELDLG  590
            PI+   DG + A+ E+ LP+ LP   D  P         +   +PLA+ T+W++V  +  
Sbjct  430  PIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTDWLEVTRE--  479

Query  591  DGLKPYTRDTNVMPQWAGSSWYELRYTDPHNSERFCAKENEAYWMGPRPAEHGPQDPGGV  650
            DG+K   R+TN MPQWAGSSWY LRY DPHN+E++   E    W+              V
Sbjct  480  DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWL-------------PV  525

Query  651  DLYVGGAEHAVLHLLYARFWHKVLYDLGHVSSREPYRRLVNQGYIQAFAYTDARGSYVPA  710
            D+YVGGAEHAVLHLLYARFWHKVLYDLG V+++EP+++L NQG I + +Y D+RG+ V++
Sbjct  526  DIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVAT  585

Query  711  EEVVERDGRFVYPGPGGEVEVFQEFGKIGKSLKNSISPDEICDDYGADTLRVYEMSMGPL  770
            + V  RDG F     G E+E  Q  +K++KSLKN ++PD++ ++YGADTLRVYEM MGPL
Sbjct  586  DKVEKRDGSFFHVETGEELE--QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPL  643

Query  771  EASRPWATKDVVGAHRFLQRVWRLVVDEQTGETRVLDGQELATGTL-RMLHRTIAGVAED  829
            +AS +W+  ++ G+++FL+RV RL+   +  E          +G+L ++ + T+ +V+E+
Sbjct  644  DASIAWSEEGLEGSRKFLDRVYRLITTKEITEE--------NSGALDKVYNETVKAVTEQ  695

Query  830  YAALRNNTAAAKLIEYTNHLTKEHREAVPRaaveplvlmlaplaphlaeelwlRLGHTTS  889
               ++ NTA A+L+ + N   KE++   +  A   + L+ +  +    E      +   S
Sbjct  696  VDQMKFNTAIAQLMVFVNAANKEDK-LFSDYAKGFVQLIAPFAPHLGEELWQALTASGES  754

Query  890  LAHGPFPVADPAYLVDDTVEYPVQVNGKVRGRVTVAADADQDTLKAAALADEKVQAFLAG  949
            ++  P P  D + LV++ VE  VQ++GKV++++ VA D  ++ L+  ALA+EKVQA +AG
Sbjct  755  ISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAG  814

Query  950  TNPRKVIVVPGRLVNLVV  967
             +  KVI VP +LVN+V+
Sbjct  815  KDIIKVIAVPNKLVNIVI  832


 Score =  129 bits (471),  Expect = 1e-30, Method: Compositional matrix adjust.
 Identities = 74/148 (50%), Positives = 99/148 (67%), Gaps = 11/148 (7%)

Query  35   IEGAWQDNWAKLGTFNVPNPVGSLAPADGSSVPDDKLFVQDMFPYPSGEGLHVGHPLGYI  94
            IE  WQ  WA   TF+            G+  +  K++  DMFPYPSG GLHVGHP GY 
Sbjct  9    IEPKWQAFWADNHTFKT-----------GTDASKPKFYALDMFPYPSGAGLHVGHPEGYT  57

Query  95   ATDVYARYFRMTGRNVLHALGFDAFGLPAEQYAVQTGTHPRTRTEANVVNFRRQLGRLGL  154
            ATD+ +R+ R  G+NVLH++G DAFGLPAEQYA++TG +P   T  N+ NF+RQ+  LG+
Sbjct  58   ATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGF  117

Query  155  GHDSRRSFSTTDVEFYKWTQWIFLQIYN  182
            + D  R  +TTD ++YKWTQWIF ++Y+
Sbjct  118  SYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1569) leuS in NC_001263


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  506 bits (1910),  Expect = 2e-144, Method: Compositional matrix adjust.
 Identities = 358/852 (43%), Positives = 513/852 (61%), Gaps = 68/852 (7%)

Query  69   YNPHAIEQKWQGQWQESGLYKFDENAPGEKFYALTMFPYPSG-NLHIGHWYANVAPDARA  127
            Y+  AIE KWQ+ W ++  +K + +A+  KFYAL MFPYPSG  LH+GH  +  A D  +
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  128  RWLRMRGYNVLFPMAFDAFGLPAENAAIKNNTNPATWTYANIERMTGQFSRMGTMIDWSR  187
            R  R +G NVL PM+ DAFGLPAE+ A+    +PA  T  NI     Q++ +G   DW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  188  KFATCDPEYYRWNQWFFIEFWKRGLAYKKGGLVNWCPKDQTVLANEQVV-NGHCERCGTA  246
               T DP+YY+W QW+F  +  +GLAY     VNW     T +ANE+V+ +G  ER G +
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  247  VERRNLSQWYLKITDYAEELL-DFSATDMPEKVRAMQTNWIGKSVGAEVTFDTPAGPE--  303
            V R+ + QW LKIT YAE LL D+   D PE ++ MQ NWIGKS GA+VTF         
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  304  TVFTTRPDTLMGATFMVLAPEHAKVKELTTDEQRAEVEAYVAAAGRKTDVERQQ-EGEKT  362
            TVFTTRPDTL GAT+ VLAPEHA V  +TT +Q   V  Y   A+ K+D+ R +   EKT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  363  GVFTGSYATHPISGHQLPIWVADYVLVTYGTGSIMAVPAHDERDFAFAKKFDLPIREVIR  422
            GV TGSYA +P++G ++P+W+ADYVL +YGTG+IMAVPAHDERD  FAK+F+L I  V+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  423  AEGSEGMGDQPSEPYSGEGQIVNSGEFDGMPGGKASIAAIIARLEERGVAKAKTTYRLRD  482
            +      G+    +++ +G  +NS+ +DG+  + ++IA ++ +LE  GV++ + TYRLRD
Sbjct  364  G------GNVEEAAFTEDGLHINSDFLDGLDKA-SAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  483  WLFARQRYWGTPIPFVHCEKCGMQPVPEDQLPVKLPENVAFTP--TGQSPLKLDEEWKTT  540
            WLF+RQRYWG PIP++H E     +VPE +LP+ LP    + P  TG+SPL    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  541  TCPCCGGPAERETDTMDTFVDSSWYMYRYLSPNYDGGPFDPSKAGL----LPVDLYTGGI  596
            T    G  + RET+TM    +SSWY  RY+ P+        +   L    LPVD+Y GG 
Sbjct  477  TRE-DGVKGRRETNTMPQWAGSSWYYLRYIDPHNTE---KLADEELLKQWLPVDIYVGGA  532

Query  597  EHAILHLLYSRFWTKVMRDMGLTTQSEPFARLRNQGMVLG--------------------  636
            EHA+LHLLY+RFW KV+ D+G+    EPF +L NQGM+LG                    
Sbjct  533  EHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRD  592

Query  637  -------------EDGEKMSKSRGNVVDPDDLVREYGADTVRAFLMFIAPWELGGPWDPQ  683
                         +   KMSKS  NVV+PDD+V +YGADT+R + MF++P + + +W  +
Sbjct  593  GSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEE  652

Query  684  GINGPSKWLSRVWNVFFEEKVSGPEEKMQGADVRFAVHSALKKVNDDFERMSFNTIISTL  743
            G++G+ K L RV  ++    ++  EE+  + D  +  + ++K V ++ ++M FNT I+ L
Sbjct  653  GLEGSRKFLDRVYRLITTKEIT--EENSGALDKVY--NETVKAVTEQVDQMKFNTAIAQL  708

Query  744  MELTNALVKAKRSPVFGTPVWEEALDIFNRMLAPVVPHIAEEIWHERGQKG-SVHTAQWP  802
            M + NA  K  +  +F+     +    F +++AP  PH++EE+W+     G S+    WP
Sbjct  709  MVFVNAANKEDK--LFS-----DYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWP  761

Query  803  QVDEAAAVRDTVTIGVQVSGKVRGEVSISKTASQEEALSAARAIAEVQKHLEGKTVVKEI  862
              DE+  V + V I VQ+ GKV++ + ++K  S+EE    A A   VQ ++ GK ++K I
Sbjct  762  SYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVI  821

Query  863  YVPGRIINIVAK  874
             VP +++NIV K
Sbjct  822  AVPNKLVNIVIK  833

1570) Hipma_1167 in NC_015318


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  506 bits (1909),  Expect = 2e-144, Method: Compositional matrix adjust.
 Identities = 354/855 (42%), Positives = 519/855 (61%), Gaps = 69/855 (8%)

Query  4    YNPAEIETKWQKIWEEkgafkakdfdkkpkfYQLEMFPYPSGR-IHMGHVRNYSIGDAIA  62
            Y+ + IE KWQ +W ++ +FK+     KPKFY L+MFPYPSG  +H+GH   Y+  D ++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKFAQGYNVLHPMGFDAFGMPAENAAINNKTHPAKWTYSNIDYMIKELKRLGFSYDWDR  122
            R+K AQG NVLHPMG DAFG+PAE+ A++   +PA  T  NI    ++++ LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  LVITCDENYYKWEQKIFIEMLKKGMVYRAKSTVNYCPTCKTVLANEQV-EDGKCWRCGDE  181
             V T D NYYKW Q IF  +  KG+ Y A   VN      T +ANE+V  DG   R G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  VIQKEMDEWFLKITDYADQLLDDMELIKDGWPEKVLIQQKNWIGKSKGAFVKFKIKGRDE  241
            V++K M +W LKIT YA++LL+D+E +  +WPE +   Q+NWIGKS GA V FK+K+ D 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV--DWPESIKDMQRNWIGKSTGANVTFKVKDTDK  241

Query  242  YLEVFTTRPDTLFGVTFVSIAPNHPKLMDLVSDeqvsvvea-----fveefkkvDRDFSK  296
             + VFTTRPDTLFG T+  +AP+H+ L+D ++  + +   A               D++K
Sbjct  242  DFTVFTTRPDTLFGATYAVLAPEHA-LVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  297  EKEGVFTGAYLINPATGEEVPLYAANFVLMDYGTGVVMAVPAHDQRDFEFATKYGLKKKI  356
            EK GV TG+Y INP  G E+P+  A++VL  YGTG +MAVPAHD+RD EFA ++ L    
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  357  VITTDGLTNNPDELDKAYTEVGVLVNSGQFDGMDNEKAKWEIVKWLEDKGLARVGYQYRL  416
            V+  + +       + A+TE G+ +NS+ +DG+D+  A   +V WLE  G++     YRL
Sbjct  361  VLEGGNVE------EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRL  414

Query  417  RDWNVSRQRYWGAPIPVVY--CPNCGIVPEKEENLPVRLPENVEITGEGGSPLAKVDEFV  474
            RDW  SRQRYWG PIP++         VPE E  L + +  ++  +G G SPLA+V + +
Sbjct  415  RDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWL  474

Query  475  NTKCPVCGADAKRETDTFDTFVESSWYFLRYCSPKYDKAIFDKQRADYWMDVDQYVGGIE  534
            +      G  ++RET+T      SSWY+LRY  P     + D +    W+ VD YVGG E
Sbjct  475  EVTRE-DGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAE  533

Query  535  HAVMHLLYARYFTKVLRDLGYANSTEPFKRLLTQGMVI-------------------KDG  575
            HAV+HLLYAR+  KVL DLG   + EPF++L+ QGM++                   +DG
Sbjct  534  HAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDG  593

Query  576  ---------------AKMSKSKGNVVDPDDIINQYGADTARLFILFAAPPEKDLEWSDEG  620
                           AKMSKS  NVV+PDD+++QYGADT R++ +F +P +  + WS+EG
Sbjct  594  SFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEG  653

Query  621  VEGAYRFLNRVWRLVYEYKDLKVIDIDINTDRLKELNYMIHSTIKKITQDFENYHFNTAI  680
            +EG+ +FL+RV RL        +   +I  +    L+ + + T+K +T++ ++  FNTAI
Sbjct  654  LEGSRKFLDRVYRL--------ITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAI  705

Query  681  AASMEFVNFLYDFKPKTEDENALFAKAIEVLLIMLNPIVPHIAEELWQ-LTGHETLIAFE  739
            A  M FVN        ++ E+ LF+     ++ ++ P+ PH++EELWQ LT+    I++ 
Sbjct  706  AQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYV  758

Query  740  PWPEYDESATVKDTVTIAITVNGKLRDTLSLPRGIAEDEVFNKAKESEKIRRHIDGKTII  799
            PWP YDES  V + V I + ++GK++  L ++++++ +E+ + A  +EK++ +I GK II
Sbjct  759  PWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDII  818

Query  800  KKIFVKDKLLNIVVK  814
            K I V +KL+NIV+K
Sbjct  819  KVIAVPNKLVNIVIK  833

1571) Deba_1412 in NC_014365


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  506 bits (1910),  Expect = 2e-144, Method: Compositional matrix adjust.
 Identities = 351/859 (41%), Positives = 542/859 (64%), Gaps = 70/859 (8%)

Query  12   YNPAEVEARWQGRWSESRLFDVDEDPAKPKYYLLEMFPYPSGR-IHMGHMRVYSIGDALA  70
            Y+ + +E++WQ+ W++++ F  + D++KPK+Y L+MFPYPSG  +H+GH   Y+  D L+
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  71   RLKRMRGFNVLHPMGWDAFGMPAENAAIAHHTHPAKWTYENIAYMRGQLKKLGFSYDWRR  130
            R+KR +G NVLHPMGWDAFG+PAE+ A+    +PA  T ENIA  + Q++ LGFSYDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  131  ELATCDPSYYRWEQLVFIKMWEKGLVYRKKSLVNWCAKCQTVLANEQV-EDGKCWRCDSE  189
            E+ T DP+YY+W Q +F K+ EKGL Y     VNW     T +ANE+V  DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  190  AQKKQMHGYFFRITDYVQELLDHTEKLPGWPERVLTMQRNWIGKSHGAEIDFPIEGRDEA  249
              +K M+   ++IT Y + LL++ E + +WPE +  MQRNWIGKS GA++ F + + D  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  250  VKVFTTRADTIFGATFMSlapehpmalelaaaagreaQVKDFIDRVGRQSFADRAD-DKQ  308
              VFTTR+DT+FGAT+ ++ + +   ++  +++++   V D+  + + +S   R+D  K+
Sbjct  243  FTVFTTRPDTLFGATY-AVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKE  301

Query  309  KEGVFTGAYCLNPVNGRRMPVYVANFVLMDYGAGAVMAVPTHDQRDFEFAKQYGLELVEV  368
            K GV TG+Y +NPVNG+ MPV +A++VL  YG+GA+MAVP+HD+RD EFAKQ+ L+++ V
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  369  IVGPDGPQGVENMERAFTDYGRLVGSGQFDGMTSDEAKRAIPQWLAEQGLGKLTVNYRLR  428
            + G +  ++      AFT+ G  + S+ +DG+    A   + +WL  +G+G+  V YRLR
Sbjct  362  LEGGNVEEA------AFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  429  DWGISRQRYWGAPIPMIHCDKCGLVPARVEDLPVVLPLDAQL--PATGGSPLPLLEGWVN  486
            DW +SRQRYWG PIP+IH +     +    +LP+VLP+  ++  ++TG SPL+ + +W++
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  487  TTCPCCQGPARRETDTMDTFVESSWYFARYACPDYVDGPLDPARVDYWMPVDQYVGGIEH  546
             T       +RRET+TM     SSWY+ RY  P+  +   D   +  W+PVD YVGG EH
Sbjct  476  VTREDG-VKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEH  534

Query  547  AVLHLLYSRFFVKVLRDLGMLKVDEPFLNLLTQGMVI-------------------KDG-  586
            AVLHLLY+RF  KVL DLG++   EPF +L+ QGM++                   +DG 
Sbjct  535  AVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGS  594

Query  587  --------------AKMSKSKGNVVDPDDMVARYGADTVRLFSLFAAPPERDLEWSDQGV  632
                          AKMSKS  NVV+PDD+V +YGADT+R++ +F +P +  + WS++G+
Sbjct  595  FFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGL  654

Query  633  EGAHRFLGRLWRLGLAVAETPAGERPGPCDGPLGELRRKAHETIKKVTEDTDRFQFNTAI  692
            EG+++FL+R+ RL ++  E    +         G L +  +ET+K VTE+ D+ +FNTAI
Sbjct  655  EGSRKFLDRVYRL-ITTKEITEENS--------GALDKVYNETVKAVTEQVDQMKFNTAI  705

Query  693  AALMELINQISLVEQdaaladdprraavlreaveaavvlISPMAPHIADELWSRL-GHAE  751
            A LM ++N  +  ++            ++ +   + V LI+P APH+++ELW  L + +E
Sbjct  706  AQLMVFVNAANKEDK------------LFSDYAKGFVQLIAPFAPHLGEELWQALTASGE  753

Query  752  FLLNVAWPVYDeaalvvaekevvFQINGKVRGKRMLPAQSDDEALKQAALADPKVRKFLG  811
             +  V+WP YDE+ LV  + E+V QI+GKV++K +++ +   E L++ ALA+ KV+  ++
Sbjct  754  SISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIA  813

Query  812  EAVVKKVIVVQGRLVNIVI  830
               + KVI V  +LVNIVI
Sbjct  814  GKDIIKVIAVPNKLVNIVI  832

1572) Q7A_1275 in NC_017857


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  506 bits (1910),  Expect = 2e-144, Method: Compositional matrix adjust.
 Identities = 344/855 (41%), Positives = 535/855 (63%), Gaps = 69/855 (8%)

Query  5    YRPDVIENAAQTWWQQHQTFRATEDTSKEKFYCLSMFPYPSGQ-LHMGHVRNYTIGDVIS  63
            Y    IE   Q+ W +++TF++  D+SK KFY L MFPYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPMGWDAFGLPAENAALKHQVPPAEWTYKNIDYMRAQLQRLGLAYDWDR  123
            R++R  G NVL+PMGWDAFGLPAE+ A+     PAE T  NI   + Q++ LG++YDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EIATCKPDYYRWEQWLFVRLFKKGLVYNKTAAVNWDPVDQTVLANEQVI-DGRGWRSGAL  182
            E+ T  P+YY+W QW+F +L+ KGL Y+   +VNW     T +ANE+V+ DG + R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERREIPQWFMKITDYAEDLRDDLQQLSGWPEQVKTMQANWIGRSEGVQITFAVADSEED  242
            V R+ + QW +KIT YAE L +DL+++ +WPE +K MQ NWIG+S G ++TF V D++ D
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LAVYTTRPDTLMGVSYLAIAAEHPL--ALRMAETNAQLQQFIEECkktdtteaaletaek  300
            ++V+TTRPDTL G +Y  +A+EH+L  A+  ++    + ++  +         +  + EK
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEK  302

Query  301  kGMATGVSVIHPVSGERIPVWVANFVLMGYGTGAVMSVPAHDQRDFEFAQKYDLPIRQVI  360
             G+ TG   I+PV+G  +PVW+A++VL +YGTGA+M+VPAHD+RD EFA++++L I  V+
Sbjct  303  TGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL  362

Query  361  EPTDDSELDLQHNAFTEKGRLVNSSQFTGLTSAEAFDAIADELTKQNKGERQVNYRLRDW  420
            E       ++++ AFTE G  +NS  + GL  A A+  + + L  +  G+ +V YRLRDW
Sbjct  363  EGG-----NVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDW  417

Query  421  GVSRQRYWGTPIPIIYCERCGAVPVPEAdlpvllpedvvvdGSG---SPIKSMPEFYQCD  477
              SRQRYWG PIPII  E   + +VPE++LP++LP    +  SG   SP+ ++ +  +  
Sbjct  418  LFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVT  477

Query  478  CPECGKPARRETDTFDTFFESSWYYARFTSADNHEAMLDQR-ADYWLPVDQYIGGIEHAV  536
              +  K +RRET+T      SSWYY R+  ++N E + D+     WLPVD Y+GG EHAV
Sbjct  478  REDGVK-GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  537  LHLLYARFFHKLLRDEGLVSGDEPFKNLLTQGMVL-------------------KDG---  574
            LHLLYARF HK+L D G+V+  EPF++L+ QGM+L                   +DG   
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFF  596

Query  575  ------------AKMSKSKGNTVDPQALIDEYGADTARLFMMFAAPPEMSLEWSDNAVEG  622
                        AKMSKS  N V+P+ ++++YGADT R++ MF +P + S+ WS++++EG
Sbjct  597  HVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEG  656

Query  623  ANRFLKRLWRSVHEHTEKGVVKDKNLTDLSEAATDLRRLAHQTLTKVGDDLGRRHTFNTA  682
            + +FL R+ R         ++  K++T+  E +  L ++ ++T+  V +++++   FNTA
Sbjct  657  SRKFLDRVYR---------LITTKEITE--ENSGALDKVYNETVKAVTEQVDQMK-FNTA  704

Query  683  IAAVMELMNGLSKFTEQDTQARAVRQEVLELVVLMLAPITPHICHALWTQLGYDKAVID-  741
            IA +M ++N+ +K   +D       +  ++L+    AP++PH+ + LW  L      I  
Sbjct  705  IAQLMVFVNAANK---EDKLFSDYAKGFVQLI----APFAPHLGEELWQALTASGESISY  757

Query  742  AQWPEVDAEALKQDKTELMIQVNGKLRSKLMVDVNAQQADIEPLAIADENVQRYIDGKTI  801
              WP  D   L ++  E+++Q++GK+++KL+V  +  + +++ +A+A+E+VQ  I GK I
Sbjct  758  VPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDI  817

Query  802  RKVILVPGRLINIVV  816
             KVI VP +L+NIV+
Sbjct  818  IKVIAVPNKLVNIVI  832

1573) leuS in NC_013956


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  506 bits (1910),  Expect = 2e-144, Method: Compositional matrix adjust.
 Identities = 354/866 (41%), Positives = 542/866 (63%), Gaps = 48/866 (5%)

Query  5    YRPEEIESRVQQQWDENETFKVTEQEGKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIA  63
            Y    IE++ Q  W +N+TFK   + +K K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKLLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCQPEYYRWEQWFFTKLYEKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T +P+YY+W QW+FTKLYEKGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITDYAeellndldtleeWPEQVKTMQRNWIGRSEGVEITFDVADSLEK  242
            V RK + QW +KIT YA E L +     +WPE +K MQRNWIG+S G ++TF V D+   
Sbjct  184  VVRKPMRQWMLKITAYA-ERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  VTVYTTRPDTFYGATYVavaaghplalqaaasnpalaDFIAECRNTKVAEADMA----TM  298
             TV+TTRPDT++GATY     +   AL  A + +  A+ +A+ +      +D+A    + 
Sbjct  243  FTVFTTRPDTLFGATYA--VLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  299  EKKGMATGLSAVHPLTGEAVPVWVANFVLMEYGTGAVMAVPAHDQRDWEFATKYDLPIKP  358
            EK G+ TG  A++P+ G  +PVW+A++VL  YGTGA+MAVPAHD+RDWEFA +++L I P
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VILNLDGSEPDVSTGAMTDKGTLFNSAECSGLDHSAGFNAIADALAAKGVGVRKVNYRLR  418
            V   L+G+  +V  +A T+ G  +NS    GLD ++++  + + L A GVG  +V YRLR
Sbjct  361  V---LEGG--NVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  419  DWGVSRQRYWGAPIPMVTLEDGTVMPTPEDQLPVILP--EDVVMDGIT-SPIKADPEWAK  475
            DW  SRQRYWG PIP++  EDGT  + PE +LP++LP   D+   G   SP+    +W  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  476  TT-VNGQPALRETDTFDTFMESSWYYARYTCADYKDGMLDPAAANYWLPVDQYVGGIEHA  534
             T  +G  + RET+T      SSWYY RY  ++  + + D    + WLPVD YVGG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  535  IMHLMYFRFFHKLLRDAGLVNSNEPAKRLLCQGMVLADAFYYLGVNGERNWVSPVDVTVE  594
            ++HL+Y RF HK+L D G+V ++EP ++L+ QGM+L+ ++        R+  +++ V+ +
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY--------RDSRGAL-VATD  586

Query  595  RDEKGRITKAVDTQGREVIYAGMSKMSKSKNNGIDPQLMVERYGADTVRLFMMFASPADM  654
            + EK R     + +  E +  + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P D 
Sbjct  587  KVEK-RDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  655  TLEWQESGVEGANRFLKRVWKLAYDHSQKGATVALDVASLNDDQKGLRRDLHKTIAKVSD  714
            ++ W E G+EG+ +FL RV +L    + K  T        +++  +L +  + T+  V++
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLI---TTKEIT--------EENSGALDKVYNETVKAVTE  694

Query  715  DIGRRQTFNTAIAAVMELMNKLTRAPQDSEQDRALMQEALLAVTRLLYPFTPHACFVLWQ  774
            ++++ + FNTAIA +M ++N        ++++  L  +   +  +L+ PF+PH    LWQ
Sbjct  695  QVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  775  TLGGQG-TIDNAEWPVADDAAMVEDALLVVVQVNGKVRGKITVAADATQELVQARAAEEP  833
            +L + G +I    WP  D++ +VE+ + +VVQ++GKV++K+ VA D ++E +Q  A  + 
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  834  LVAKYLDGVSIRKVIYVPGKLLNLVV  859
             V   + G  I KVI VP KL+N+V+
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVI  832

1574) leuS in NC_015564


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  506 bits (1908),  Expect = 3e-144, Method: Compositional matrix adjust.
 Identities = 355/755 (48%), Positives = 502/755 (67%), Gaps = 79/755 (10%)

Query  226  LVYHSNAQVNWCPGLGTVLANEEVTADGRSERGNFPVFRKELKQWMMRITTYAdrllddl  285
            L Y+++  VNW   LGT +ANEEV +DG SERG +PV RK ++QWM++IT+YA+RLL+DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  286  dlldWPDKVKTMQRNWIGRSRGANVEF-ATDSGRDIEVFTTRPDTLFGATYMVLAPEHEL  344
            + +DWP+ +K MQRNWIG+S GANV F   D+++D+ VFTTRPDTLFGATY VLAPEH L
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  345  VDTLISAEWPTGTDARWTGGAASPAEAVAKYRASIASKTDLERQE-NKEKTGVFLGSFAT  403
            VD++ +++                AEAVA Y+   + K+DL R +  KEKTGV  GS+A 
Sbjct  268  VDAITTSD---------------QAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAI  312

Query  404  NPVNGHKIPVFIADYVLTGYGTGAIMAVPAHDVRDFEFATTFGLEIVRVIAADTEGSDTS  463
            NPVNG  +PV IADYVL++YGTGAIMAVPAHD RD EFA  F L+I+ V+    EG++  
Sbjct  313  NPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL----EGGNVE  368

Query  464  APETLDAAFTGDGVGINSANDSGLNINGLRVDEAKTRAISWLEEQGRGKGTVQYKLRDWL  523
                 +AAFT DG+ INS       ++GL    A ++ + WLE +G G+  V Y+LRDWL
Sbjct  369  -----EAAFTEDGLHINSD-----FLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWL  418

Query  524  FARQRYWGEPFPIVYDEDGVTYALPDSMLPVELPDLTDYAPVTFDPDDANSEPSPPLAKA  583
            F+RQRYWGEP+PI+  EDG + A+P+S LP+ LP   D  P        ++   +PLA+ 
Sbjct  419  FSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANV  470

Query  584  TDWVNVELDLGDGLKTYRRDTNVMPQWAGSSWYQLRYIDPTNQDEFCAKDNEAYWVGPRP  643
            TDW++V  +  DG+K  RR+TN MPQWAGSSWY LRYIDP N + +   +    W+    
Sbjct  471  TDWLEVTRE--DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWL----  523

Query  644  EIHGPHDPGGIDLYVGGVEHAVLHLLYARFWHKVLHDLGHVSSVEPYRRLFNQGYIQAFA  703
                      +D+YVGG EHAVLHLLYARFWHKVL DLG V++ EP+++LFNQG I + +
Sbjct  524  ---------PVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS  574

Query  704  YTDSRGVYVPADEVEEKGDKFFWTGPDGQTVEVNQEYGKMGKSLKNSVTPDEIAEDFGAD  763
            Y DSRG  V++D VE +++ FF         E++Q  +KM+KSLKN V PD++ E++GAD
Sbjct  575  YRDSRGALVATDKVEKRDGSFF---HVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGAD  631

Query  764  TLRVYEMSMGPLDASRPWATKDVIGAHRFLQRVWRLVIDEESGAMKVVERELDETTLRVV  823
            TLRVYEM MGPLDAS +W+  ++ G+++FL+RV RL+      + K +  E   +  +V 
Sbjct  632  TLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLI------TTKEITEENSGALDKVY  685

Query  824  NRTIAGVDEEYASLRMNTAGAKLIELTN------HLTKAYPNGAPRSAVEPLVLMMAPLA  877
            N T+ +V E+   ++ NTA A+L+ + N       L   Y++G        +V ++AP+A
Sbjct  686  NETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKG--------FVQLIAPFA  737

Query  878  PHVAEELWSRL-GHETPLAHGPFPTADERWLADETLEYPIQVNGKVRGRINVPADSSREH  936
            PH++EELW  L +   +++  P P+ DE  L ++ +E  +Q++GKV++++ V+ D SRE+
Sbjct  738  PHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREE  797

Query  937  VEQVALADDKIATLIEGKTPRKVIVVPGKMVNIVL  971
            +++VALA++K+ + I GK   KVI VP K+VNIV+
Sbjct  798  LQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832


 Score =  133 bits (488),  Expect = 6e-32, Method: Compositional matrix adjust.
 Identities = 73/145 (51%), Positives = 98/145 (68%), Gaps = 7/145 (4%)

Query  33   IERRWQERWNELGSFHAPNPTGPLAGDVPEDKLFVLDMFPYPSGAGLHVGHPLGFIATDV  92
            IE +WQ  W +  +F +       + D +  K++ LDMFPYPSGAGLHVGHP G+ ATD+
Sbjct  9    IEPKWQAFWADNHTFKT-------GTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDI  61

Query  93   YARYHRMRGHNVLHTMGFDSFGLPAEQYAVQTGTHPRTTTEANIERYLAQIRRLGLGHDE  152
             +R+ R +GHNVLH MG D+FGLPAEQYA++TG +P   T  NI  +  QI  LG++ D 
Sbjct  62   LSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDW  121

Query  153  RRRVATTDTDFYHWTQWIFLQIYNS  177
             R V TTD ++Y WTQWIF ++Y+ 
Sbjct  122  DREVNTTDPNYYKWTQWIFTKLYEK  146

1575) leuS in NC_004129


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  506 bits (1908),  Expect = 3e-144, Method: Compositional matrix adjust.
 Identities = 360/875 (42%), Positives = 561/875 (65%), Gaps = 60/875 (6%)

Query  5    YQPREIEAAAQLFWDEQKSFEVSEQPGKETYYCLSMFPYPSGK-LHMGHVRNYTIGDVIS  63
            Y+   IE+  Q FW ++ +F  + +++K  +Y L MFPYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMQGKNVLQPMGWDAFGMPAENAAMKNNVAPAKWTYENIAYMKTQLRSLGLAVDWSR  123
            R++R QG NVL+PMGWDAFG+PAE+ AM     PA  T ENIA  K Q+ +LG++ DW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVTTCKPDYYRWEQWLFTRLFEKGVIYRKNGTVNWDPIDQTVLANEQVI-DGRGWRSGAL  182
            EV T  P+YY+W QW+FT+L+EKG+ Y  +  VNW     T +ANE+V+ DG + R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  IEKREIPMYYFKITAYADELLESLDELPGWPEQVKTMQRNWIGKSRGMEVQFPYDQASIG  242
            + ++ +    +KITAYA+ LLE L+E+ +WPE +K MQRNWIGKS G +V F   ++  +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  EAGTLKVFTTRPDTLMGATYVAVAAEHPL-ATLAAQDNPELQAFIAECKGGSVAEADMA-  300
                + VFTTRPDTL GATY  +A+EH+L  ++++ D++E    +A+ K  +   +D+A 
Sbjct  243  ----FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEA---VADYKRQASLKSDLAR  295

Query  301  ---TQEKKGLPTSLFVEHPLTGEKLPVWVANYVLMHYGDGAVMAVPAHDERDFEFATKYN  357
               ++EK G+ T+ +  +P+ G  +PVW+A+YVL  YG GA+MAVPAHDERD EFA ++N
Sbjct  296  TDLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFN  355

Query  358  LPIKAVVRTSAGDETPAPWQDAYGEHGELINSGEFNGLDFPGAFDAIEVALLKKNLGQSR  417
            L I +V+  +  +E+      A+ E+G  INS+ ++GLD ++A+  +   L    +G+  
Sbjct  356  LDIIPVLEGGNVEEA------AFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNEN  409

Query  418  TQFRLRDWGISRQRYWGCPIPIIH--CDSCGDvpvpqeqlpvvlpedvvpdGAG-SPLAR  474
              +RLRDW +SRQRYWG PIPIIH   ++   VP ++  L + +  D+ P G+G SPLA 
Sbjct  410  VTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLAN  469

Query  475  MPEFYECSCPKCGAPAKRETDTMDTFVESSWYYARYASPHYEGGLVDPAAANHWLPVDQY  534
            + +  E +    G  ++RET+TM     SSWYY RY  PH    L D    ++WLPVD Y
Sbjct  470  VTDWLEVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIY  528

Query  535  IGGIEHAILHLLYARFFHKLMRDEGLVSSNEPFKNLLTQGMVIAETYYRREANGSYTWYN  594
            +GG EHA+LHLLYARF HK++ D G+V+++EPF++L+ QGM+++ +Y  R++ G+     
Sbjct  529  VGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY--RDSRGA-----  581

Query  595  PADVELERDSKAKIIGAKLISDGLPVEIG-GTEKMAKSKNNGVDPQSMIEQYGADTCRLF  653
                 L    K    ++ ++      E+  +  KM+KS +N V+P+ ++EQYGADT R++
Sbjct  582  -----LVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVY  636

Query  654  MMFASPPDMSLEWSDSGVEGAHRFLKRVWRLAQA-HVSQGLPGALDIATLSDEQKAIRRA  712
             MF +P D S+ WS+ G+EG+++FL RV RL  + ++++  +GALD            + 
Sbjct  637  EMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALD------------KV  684

Query  713  IHLAIKQASQDVGQHHKFNTAIAQVMTLMNVLEKAPQGSEQDRALLQEGLQTVALLLAPI  772
             + ++K  +++V ++ KFNTAIAQ+M ++N       +++++  L+ +  +    L+AP+
Sbjct  685  YNETVKAVTEQV-DQMKFNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPF  736

Query  773  TPHISHELWGQLGQSGAIID-AGWPALDESALVQDSLQLVIQVNGKLRGQIEMPasasre  831
            +PH+++ELW  L  SG  I    WP+ DES LV++ +++V+Q++GK+++++ ++   SRE
Sbjct  737  APHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSRE  796

Query  832  eveaaarsnenvLRFTEGLTIRKVIVVPGKLVNIV  866
            E++  A +NE+V     G  I KVI VP KLVNIV
Sbjct  797  ELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIV  831

1576) leuS in NC_021237


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  506 bits (1907),  Expect = 3e-144, Method: Compositional matrix adjust.
 Identities = 358/875 (41%), Positives = 561/875 (65%), Gaps = 60/875 (6%)

Query  5    YQPREIEAAAQSFWDEQKSFEVSEQPGKETYYCLSMFPYPSGK-LHMGHVRNYTIGDVIS  63
            Y+   IE+  Q+FW ++ +F  + +++K  +Y L MFPYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMQGKNVLQPMGWDAFGMPAENAAMKNNVAPAKWTYENIAYMKTQLRSLGLAVDWSR  123
            R++R QG NVL+PMGWDAFG+PAE+ AM     PA  T ENIA  K Q+ +LG++ DW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVTTCKPDYYRWEQWLFTRLFEKGVIYRKNGTVNWDPIDQTVLANEQVI-DGRGWRSGAL  182
            EV T  P+YY+W QW+FT+L+EKG+ Y  +  VNW     T +ANE+V+ DG + R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  IEKREIPMYYFKITAYADELLESLDELPGWPEQVKTMQRNWIGKSRGMEVQFPYDQASIG  242
            + ++ +    +KITAYA+ LLE L+E+ +WPE +K MQRNWIGKS G +V F   ++  +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  EAGTLKVFTTRPDTLMGATYVAVAAEHPL-ATLAAQDNPELQAFIAECKGGSVAEADMA-  300
                + VFTTRPDTL GATY  +A+EH+L  ++++ D++E    +A+ K  +   +D+A 
Sbjct  243  ----FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEA---VADYKRQASLKSDLAR  295

Query  301  ---TQEKKGLPTSLFVEHPLTGEKLPVWVANYVLMHYGDGAVMAVPAHDERDFEFATKYN  357
               ++EK G+ T+ +  +P+ G  +PVW+A+YVL  YG GA+MAVPAHDERD EFA ++N
Sbjct  296  TDLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFN  355

Query  358  LPIKAVVRTSAGNETPAPWQDAYGEHGELINSGEFNGLDFPGAFDAIEVALLKKNLGQSR  417
            L I +V+  +  +E+      A+ E+G  INS+ ++GLD ++A+  +   L    +G+  
Sbjct  356  LDIIPVLEGGNVEEA------AFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNEN  409

Query  418  TQFRLRDWGISRQRYWGCPIPIIH--CDSCGDvpvpqeqlpvvlpedvvpdGAG-SPLAR  474
              +RLRDW +SRQRYWG PIPIIH   ++   VP ++  L + +  D+ P G+G SPLA 
Sbjct  410  VTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLAN  469

Query  475  MPEFYECSCPKCGAPAKRETDTMDTFVESSWYYARYASPHYEGGLVDPAAANHWLPVDQY  534
            + +  E +    G  ++RET+TM     SSWYY RY  PH    L D    ++WLPVD Y
Sbjct  470  VTDWLEVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIY  528

Query  535  IGGIEHAILHLLYARFFHKLMRDEGLVSSNEPFKNLLTQGMVIAETYYRREANGSYTWYN  594
            +GG EHA+LHLLYARF HK++ D G+V+++EPF++L+ QGM+++ +Y  R++ G+     
Sbjct  529  VGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY--RDSRGA-----  581

Query  595  PADVELERDSKAKIIGAKLISDGLPVEIG-GTEKMAKSKNNGVDPQSMIEQYGADTCRLF  653
                 L    K    ++ ++      E+  +  KM+KS +N V+P+ ++EQYGADT R++
Sbjct  582  -----LVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVY  636

Query  654  MMFASPPDMSLEWSDSGVEGAHRFLKRVWRLAQA-HVSQGLPGDLDVATLSDEQKAIRRA  712
             MF +P D S+ WS+ G+EG+++FL RV RL  + ++++  +G LD            + 
Sbjct  637  EMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALD------------KV  684

Query  713  IHLAIKQASQDVGQHHKFNTAIAQVMTLMNVLEKAPQGSEQDRALLQEGLQTVALLLAPI  772
             + ++K  +++V ++ KFNTAIAQ+M ++N       +++++  L+ +  +    L+AP+
Sbjct  685  YNETVKAVTEQV-DQMKFNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPF  736

Query  773  TPHISHELWGQLGQGGAIID-AGWPALDESALVQDSLQLVIQVNGKLRGQIEMPasasre  831
            +PH+++ELW  L  +G  I    WP+ DES LV++ +++V+Q++GK+++++ ++   SRE
Sbjct  737  APHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSRE  796

Query  832  eveaaarsnenvLRFTEGLTIRKVIVVPGKLVNIV  866
            E++  A +NE+V     G  I KVI VP KLVNIV
Sbjct  797  ELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIV  831

1577) MIP_00064 in NC_018612


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  506 bits (1907),  Expect = 4e-144, Method: Compositional matrix adjust.
 Identities = 348/742 (47%), Positives = 502/742 (68%), Gaps = 61/742 (8%)

Query  232  LVYRADSMVNWCPGLGTVLANEEVTADGRSDRGNFPVFRKRLRQWMMRITAYSdrllddl  291
            L Y A+  VNW   LGT +ANEEV +DG S+RG +PV RK +RQWM++ITAY++RLL+DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  292  elldWPEPVKAMQRNWIGRSTGAKALFAATKADGEAVDIEVFTTRPDTLFGATYLVLAPE  351
            E +DWPE++K MQRNWIG+STGA+  F    +D    D+ VFTTRPDTLFGATY VLAPE
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDK---DFTVFTTRPDTLFGATYAVLAPE  264

Query  352  HDLVDELVAAAWPDGTDPRWTYRAATPGEAVDAYRKAIASKSDLERQE-SKAKTGVFLGS  410
            H LVD + ++                 +EAV  Y++  + KSDL R + +K KTGV  GS
Sbjct  265  HALVDAITTSD---------------QAEAVADYKRQASLKSDLARTDLAKEKTGVWTGS  309

Query  411  YATNPTNGKPVPIFIADYVLAGYGTGAIMAVPGHDQRDWDFAHEFGLPIVEVIAGGDISE  470
            YA NP NGK +P+ IADYVLA+YGTGAIMAVP+HD+RDW+FA +F L I+ V+ GG++ E
Sbjct  310  YAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEE  369

Query  471  AAYAGDGVLVNSGYLDGLDVAAAKEKITARLESEGRGQARIEFKLRDWLFARQRYWGEPF  530
            AA++ DG+ +NS++LDGLD A+A  K+  +LE+EG G+  + ++LRDWLF+RQRYWGEP+
Sbjct  370  AAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPI  429

Query  531  PIVYDADGRAHALDEAALPVELPDVPDYSPVLFdpddadsepsppLAKATEWVHVELDLG  590
            PI+   DG + A+ E+ LP+ LP   D  P         +   +PLA+ T+W++V  +  
Sbjct  430  PIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTDWLEVTRE--  479

Query  591  DGLKPYTRDTNVMPQWAGSSWYELRYTDPHNSERFCAKENEAYWMGPRPAEHGPQDPGGV  650
            DG+K   R+TN MPQWAGSSWY LRY DPHN+E++   E    W+              V
Sbjct  480  DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWL-------------PV  525

Query  651  DLYVGGAEHAVLHLLYARFWHKVLYDLGHVSSREPYRRLVNQGYIQAFAYTDARGSYVPA  710
            D+YVGGAEHAVLHLLYARFWHKVLYDLG V+++EP+++L NQG I + +Y D+RG+ V++
Sbjct  526  DIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVAT  585

Query  711  EEVVERDGRFVYPGPGGEVEVFQEFGKIGKSLKNSISPDEICDDYGADTLRVYEMSMGPL  770
            + V  RDG F     G E+E  Q  +K++KSLKN ++PD++ ++YGADTLRVYEM MGPL
Sbjct  586  DKVEKRDGSFFHVETGEELE--QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPL  643

Query  771  EASRPWATKDVVGAHRFLQRVWRLVVDEQTGETRVLDGPAQELATGTL-RMLHRTIAGVA  829
            +AS +W+  ++ G+++FL+RV RL+   +  E            +G+L ++ + T+ +V+
Sbjct  644  DASIAWSEEGLEGSRKFLDRVYRLITTKEITEE----------NSGALDKVYNETVKAVT  693

Query  830  EDYAALRNNTAAAKLIEYTNHLTKEHR--EEVPRaaveplvlmlaplaphlaeelwlRLG  887
            E+   ++ NTA A+L+ + N   KE++   + +++ V+ +    + L+ +L + L    +
Sbjct  694  EQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALT---A  750

Query  888  HTTSLAHGPFPVADPAYLVDDTVEYPVQVNGKVRGRVTVAADADQDTLKAAALADEKVQA  947
               S++  P P  D + LV++ VE  VQ++GKV++++ VA D  ++ L+  ALA+EKVQA
Sbjct  751  SGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQA  810

Query  948  FLAGANPRKVIVVPGRLVNLVV  969
             +AG +  KVI VP +LVN+V+
Sbjct  811  EIAGKDIIKVIAVPNKLVNIVI  832


 Score =  129 bits (471),  Expect = 1e-30, Method: Compositional matrix adjust.
 Identities = 74/148 (50%), Positives = 99/148 (67%), Gaps = 11/148 (7%)

Query  35   IEGAWQDNWAKLGTFNVPNPVGSLAPPDGSSVPDDKLFVQDMFPYPSGEGLHVGHPLGYI  94
            IE  WQ  WA   TF+            G+  +  K++  DMFPYPSG GLHVGHP GY 
Sbjct  9    IEPKWQAFWADNHTFKT-----------GTDASKPKFYALDMFPYPSGAGLHVGHPEGYT  57

Query  95   ATDVYARYFRMTGRNVLHALGFDAFGLPAEQYAVQTGTHPRTRTEANVVNFRRQLGRLGL  154
            ATD+ +R+ R  G+NVLH++G DAFGLPAEQYA++TG +P   T  N+ NF+RQ+  LG+
Sbjct  58   ATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGF  117

Query  155  GHDSRRSFSTTDVEFYKWTQWIFLQIYN  182
            + D  R  +TTD ++YKWTQWIF ++Y+
Sbjct  118  SYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1578) leuS in NC_021500


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  506 bits (1907),  Expect = 4e-144, Method: Compositional matrix adjust.
 Identities = 353/866 (41%), Positives = 539/866 (63%), Gaps = 48/866 (5%)

Query  5    YRPEDIESKVQRHWEEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIS  63
            Y    IE+K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYAdellndldnldHWPDTVKTMQRNWIGRSEGVEITFDVQNSDQK  242
            V RK + QW +KITAYA E L +  +  +WP+++K MQRNWIG+S G ++TF V+++D+ 
Sbjct  184  VVRKPMRQWMLKITAYA-ERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFIGATYLavaaghplaqqaaaSKPELASFIDECRNTKVAEADMA----TM  298
            +TV+TTRPDT++GATY     +   A   A + ++ A  + + +      +D+A    + 
Sbjct  243  FTVFTTRPDTLFGATY--AVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK  300

Query  299  EKKGVDTGLKAIHPLTGEAIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFATKYNLPIKA  358
            EK GV TG  AI+P+ G  +PVW A++VL  YGTGA+MAVP+HD+RD EFA ++NL I +
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VILNADGSAPDLSEQAMTDKGVLFNSGEFDGLDFNAAFNAIADKLAAKGVGERKVNFRLR  418
            V+      + ++ E A T+ G+ +NS+ +DGLD  +A+  + + L A GVG+ +V +RLR
Sbjct  361  VL-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  419  DWGVSRQRYWGAPIPMVTLEDGTVIPTPEDQLPVILP--EDVVMDGIT-SPIKADPEWAK  475
            DW  SRQRYWG PIP++  EDGT  + PE +LP++LP   D+   G   SP+    +W  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  476  TT-VNGQPALRETDTFDTFMESSWYYARYTCPQHNEGMLDPKAANYWLPVDIYIGGIEHA  534
             T  +G  + RET+T      SSWYY RY  P++ E + D    + WLPVDIY+GG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  535  IMHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPKDAIVE  594
            ++HLLY RF HK++ D G+V + EP ++L+ QGM+L+ ++      + R  + + D +  
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-----RDSRGALVATDKVEK  590

Query  595  RDEKGRIVKATDPAGHELVYTGMSKMSKSKNNGIDPQEMVERYGADTVRLFMMFASPADM  654
            RD     V + +   +     + +KMSKS +N ++P+++VE+YGADT+R++ MF +P D 
Sbjct  591  RDGSFFHVETGEELEQ-----APAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  655  TLEWQESGVEGANRFLKRVWKLVYEHTargavaaldlaalsedqqalRRDVHKTIAKVSD  714
            ++ W E G+EG+ +FL RV +L+                  E+  AL +  + T+  V++
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLI-----------TTKEITEENSGALDKVYNETVKAVTE  694

Query  715  DIGRRQTFNTAIAAIMELMNKLAKAPQESEQDRALMQEALLAVVRMLNPFTPHASFTLWQ  774
            ++++ + FNTAIA +M ++N        ++++  L  +   + V+++ PF+PH +  LWQ
Sbjct  695  QVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  775  ELGGEGD-IDNAPWPVADEKAMVENTTLVVVQVNGKVRGKITVAVDATEEQVRERAGQEH  833
             L + G+ I   PWP  DE  +VEN   +VVQ++GKV++K+ VA D + E+++E A  ++
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  834  LVAKYLDGVTVRKVIYVPGKLLNLVV  859
             V   + G  + KVI VP KL+N+V+
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVI  832

1579) OCU_00490 in NC_016946


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  505 bits (1906),  Expect = 4e-144, Method: Compositional matrix adjust.
 Identities = 348/742 (47%), Positives = 502/742 (68%), Gaps = 61/742 (8%)

Query  232  LVYRADSMVNWCPGLGTVLANEEVTADGRSDRGNFPVFRKRLRQWMMRITAYSdrllddl  291
            L Y A+  VNW   LGT +ANEEV +DG S+RG +PV RK +RQWM++ITAY++RLL+DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  292  elldWPEPVKAMQRNWIGRSTGAKALFAATKADGEAVDIEVFTTRPDTLFGATYLVLAPE  351
            E +DWPE++K MQRNWIG+STGA+  F    +D    D+ VFTTRPDTLFGATY VLAPE
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDK---DFTVFTTRPDTLFGATYAVLAPE  264

Query  352  HDLVDELVAAAWPDGTDPRWTYRAATPGEAVDAYRKAIASKSDLERQE-SKAKTGVFLGS  410
            H LVD + ++                 +EAV  Y++  + KSDL R + +K KTGV  GS
Sbjct  265  HALVDAITTSD---------------QAEAVADYKRQASLKSDLARTDLAKEKTGVWTGS  309

Query  411  YATNPTNGKPVPIFIADYVLAGYGTGAIMAVPGHDQRDWDFAHEFGLPIVEVIAGGDISE  470
            YA NP NGK +P+ IADYVLA+YGTGAIMAVP+HD+RDW+FA +F L I+ V+ GG++ E
Sbjct  310  YAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEE  369

Query  471  AAYAGDGVLVNSGYLDGLDVAAAKEKITARLESEGRGQARIEFKLRDWLFARQRYWGEPF  530
            AA++ DG+ +NS++LDGLD A+A  K+  +LE+EG G+  + ++LRDWLF+RQRYWGEP+
Sbjct  370  AAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPI  429

Query  531  PIVYDADGRAHALDEAALPVELPDVPDYSPVLFdpddadsepsppLAKATEWVHVELDLG  590
            PI+   DG + A+ E+ LP+ LP   D  P         +   +PLA+ T+W++V  +  
Sbjct  430  PIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTDWLEVTRE--  479

Query  591  DGLKPYTRDTNVMPQWAGSSWYELRYTDPHNSERFCAKENEAYWMGPRPAEHGPQDPGGV  650
            DG+K   R+TN MPQWAGSSWY LRY DPHN+E++   E    W+              V
Sbjct  480  DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWL-------------PV  525

Query  651  DLYVGGAEHAVLHLLYARFWHKVLYDLGHVSSREPYRRLVNQGYIQAFAYTDARGSYVPA  710
            D+YVGGAEHAVLHLLYARFWHKVLYDLG V+++EP+++L NQG I + +Y D+RG+ V++
Sbjct  526  DIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVAT  585

Query  711  EEVVERDGRFVYPGPGGEVEVFQEFGKIGKSLKNSISPDEICDDYGADTLRVYEMSMGPL  770
            + V  RDG F     G E+E  Q  +K++KSLKN ++PD++ ++YGADTLRVYEM MGPL
Sbjct  586  DKVEKRDGSFFHVETGEELE--QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPL  643

Query  771  EASRPWATKDVVGAHRFLQRVWRLVVDEQTGETRVLDGPAQELATGTL-RMLHRTIAGVA  829
            +AS +W+  ++ G+++FL+RV RL+   +  E            +G+L ++ + T+ +V+
Sbjct  644  DASIAWSEEGLEGSRKFLDRVYRLITTKEITEE----------NSGALDKVYNETVKAVT  693

Query  830  EDYAALRNNTAAAKLIEYTNHLTKEHR--EEVPRaaveplvlmlaplaphlaeelwlRLG  887
            E+   ++ NTA A+L+ + N   KE++   + +++ V+ +    + L+ +L + L    +
Sbjct  694  EQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALT---A  750

Query  888  HTTSLAHGPFPVADPAYLVDDTVEYPVQVNGKVRGRVTVAADADQDTLKAAALADEKVQA  947
               S++  P P  D + LV++ VE  VQ++GKV++++ VA D  ++ L+  ALA+EKVQA
Sbjct  751  SGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQA  810

Query  948  FLAGANPRKVIVVPGRLVNLVV  969
             +AG +  KVI VP +LVN+V+
Sbjct  811  EIAGKDIIKVIAVPNKLVNIVI  832


 Score =  129 bits (471),  Expect = 1e-30, Method: Compositional matrix adjust.
 Identities = 74/148 (50%), Positives = 99/148 (67%), Gaps = 11/148 (7%)

Query  35   IEGAWQDNWAKLGTFNVPNPVGSLAPPDGSSVPDDKLFVQDMFPYPSGEGLHVGHPLGYI  94
            IE  WQ  WA   TF+            G+  +  K++  DMFPYPSG GLHVGHP GY 
Sbjct  9    IEPKWQAFWADNHTFKT-----------GTDASKPKFYALDMFPYPSGAGLHVGHPEGYT  57

Query  95   ATDVYARYFRMTGRNVLHALGFDAFGLPAEQYAVQTGTHPRTRTEANVVNFRRQLGRLGL  154
            ATD+ +R+ R  G+NVLH++G DAFGLPAEQYA++TG +P   T  N+ NF+RQ+  LG+
Sbjct  58   ATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGF  117

Query  155  GHDSRRSFSTTDVEFYKWTQWIFLQIYN  182
            + D  R  +TTD ++YKWTQWIF ++Y+
Sbjct  118  SYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1580) leuS in NC_016906


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  505 bits (1906),  Expect = 5e-144, Method: Compositional matrix adjust.
 Identities = 357/734 (49%), Positives = 486/734 (67%), Gaps = 58/734 (7%)

Query  232  LVYQSDSLVNWCPGLGTVLANEEVTADGRSDRGNFPVFRKHLRQWMMRITAYSdrllddl  291
            L Y+++  VNW   LGT +ANEEV +DG S+RG +PV RK +RQWM++ITAY++RLL+DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  292  edldWPEKVKTMQRNWIGRSRGAQVHFAAGGTTIE--VFTTRPDTLFGATYMVLSPEHPL  349
            E++DWPE +K MQRNWIG+S GA+V F   +T  +  VFTTRPDTLFGATY VL+PEH+L
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  350  VDELTADAWPDGTDPRWTGGGADTPtaaiaayrtaiaaKSDLERQE-NKEKTGVFTGTYA  408
            VD +T+   +D +++             +A Y+   + KSDL R +  KEKTGV TG+YA
Sbjct  268  VDAITT---SDQAEA-------------VADYKRQASLKSDLARTDLAKEKTGVWTGSYA  311

Query  409  TNPVDGREIPVFIADYVLMGYGTGAIMAVPAHDGRDHEFATVFGLPILEVIGSKQGVATE  468
             NPV+G+E+PV IADYVL +YGTGAIMAVPAHD RD EFA  F L I+ V+ +   V   
Sbjct  312  INPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEG-GNVEEA  370

Query  469  PFVGDGPLVNSGFLDGLRVDEAKAAITAWLEERGAGEGTIQYKLRDWLFARQRYWGEPFP  528
            +F  DG  +NS+FLDGL    A A +  WLE  G G+  + Y+LRDWLF+RQRYWGEP+P
Sbjct  371  AFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIP  430

Query  529  IVYDADGQAHALPESMLPVELPEVDDYAPVsfdpedsgsepsppLAKATEWMTVELDLG-  587
            I+   DG + A+PES LP+ LP   D  P        ++   +PLA+ T+W+ V  + G 
Sbjct  431  IIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTDWLEVTREDGV  482

Query  588  DGRQTYTRDANVMPQWAGSSWYQLRYIDPTNDETLCAKENEAYWMGPRPALHGPNDPGGL  647
             GR    R++N MPQWAGSSWY LRYIDP N E L   E    W+              +
Sbjct  483  KGR----RETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLP-------------V  525

Query  648  DLYIGGVEHAVLHLLYSRFWHKVLFDLGYVTSREPYRKLFNQGMIQAYAYADSRGIYVPA  707
            D+Y+GG EHAVLHLLY+RFWHKVL+DLG V ++EP++KLFNQGMI + +Y DSRG  V++
Sbjct  526  DIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVAT  585

Query  708  EEVTERDGKFFY--NGDEVSQEYGKMGKSLKNSVTPDDIAADYGADTLRLYEMYMGPLDQ  765
            + V  RDG FF    G+E+ Q  +KM+KSLKN V PDD+  +YGADTLR+YEM+MGPLD 
Sbjct  586  DKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  766  SRPWATKDVVGLQRFLQRVWRLVVDEETGTVRVTDAELDDVTKRLLHTTIAEVREEFAGL  825
            S +W+  ++ G ++FL+RV RL+   E     +T+ + + + K + + T+  V E+   +
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLITTKE-----ITEENSGALDK-VYNETVKAVTEQVDQM  699

Query  826  RFNIAVAALIKLTNHLTKQFEGGAPRAAVEPLVTMLAPLAPHIAEELWHRL-GHDELLVR  884
            +FN A+A L+ + N   K  E+         +V ++AP+APH++EELW+ L + +E +  
Sbjct  700  KFNTAIAQLMVFVNAANK--EDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISY  757

Query  885  GPFPDPDPQWLVADSVEIAVQVKGKVKSRITVAADADEATLREVALADEKIVALLDG-EP  943
             P P  D   LV + VEI VQ+KGKVK+++ VA D     L+EVALA+EK+ A + G + 
Sbjct  758  VPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDI  817

Query  944  RKVIIVPGRLVNIV  957
             KVI VP +LVNIV
Sbjct  818  IKVIAVPNKLVNIV  831


 Score =  127 bits (465),  Expect = 3e-30, Method: Compositional matrix adjust.
 Identities = 73/153 (48%), Positives = 100/153 (66%), Gaps = 16/153 (10%)

Query  25   IEQRWQRNWSDRHAFEAPNPVGPLAGDLSAFGGGAPDSPEKVFVQDMFPYPSGAGLHVGH  84
            IE +WQ  W+D H+F +                G+  S  K +  DMFPYPSGAGLHVGH
Sbjct  9    IEPKWQAFWADNHTFKT----------------GTDASKPKFYALDMFPYPSGAGLHVGH  52

Query  85   PLGFIASDVFARYQRMIGRNVLHTMGFDSFGLPAEQYAVQTGTHPRTTTEANIERYLGQI  144
            P G+ A+D+++R++R  G+NVLH MG D+FGLPAEQYA++TG +P   T  NI  +  QI
Sbjct  53   PEGYTATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQI  112

Query  145  RRLGLGHDERRRVATTDVDFYRWTQWIFLQIYN  177
              LG++ D  R V TTD ++Y+WTQWIF ++Y+
Sbjct  113  NALGFSYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1581) OCQ_00480 in NC_016948


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  505 bits (1906),  Expect = 5e-144, Method: Compositional matrix adjust.
 Identities = 347/740 (47%), Positives = 496/740 (68%), Gaps = 57/740 (7%)

Query  232  LVYRADSMVNWCPGLGTVLANEEVTADGRSDRGNFPVFRKRLRQWMMRITAYSdrllddl  291
            L Y A+  VNW   LGT +ANEEV +DG S+RG +PV RK +RQWM++ITAY++RLL+DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  292  elldWPEPVKAMQRNWIGRSTGAKALFAATKADGEAVDIEVFTTRPDTLFGATYLVLAPE  351
            E +DWPE++K MQRNWIG+STGA+  F    +D    D+ VFTTRPDTLFGATY VLAPE
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDK---DFTVFTTRPDTLFGATYAVLAPE  264

Query  352  HDLVDELVAAAWPDGTDPRWTYRAATPGEAVDAYRKAIASKSDLERQE-SKAKTGVFLGS  410
            H LVD + ++                 +EAV  Y++  + KSDL R + +K KTGV  GS
Sbjct  265  HALVDAITTSD---------------QAEAVADYKRQASLKSDLARTDLAKEKTGVWTGS  309

Query  411  YATNPTNGKPVPIFIADYVLAGYGTGAIMAVPGHDQRDWDFAHEFGLPIVEVIAGGDISE  470
            YA NP NGK +P+ IADYVLA+YGTGAIMAVP+HD+RDW+FA +F L I+ V+ GG++ E
Sbjct  310  YAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEE  369

Query  471  AAYAGDGVLVNSGYLDGLDVAAAKEKITARLESEGRGQARIEFKLRDWLFARQRYWGEPF  530
            AA++ DG+ +NS++LDGLD A+A  K+  +LE+EG G+  + ++LRDWLF+RQRYWGEP+
Sbjct  370  AAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPI  429

Query  531  PIVYDADGRAHALDEAALPVELPDVPDYSPVLFdpddadsepsppLAKATEWVHVELDLG  590
            PI+   DG + A+ E+ LP+ LP   D  P         +   +PLA+ T+W++V  +  
Sbjct  430  PIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTDWLEVTRE--  479

Query  591  DGLKPYTRDTNVMPQWAGSSWYELRYTDPHNSERFCAKENEAYWMGPRPAEHGPQDPGGV  650
            DG+K   R+TN MPQWAGSSWY LRY DPHN+E++   E    W+              V
Sbjct  480  DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWL-------------PV  525

Query  651  DLYVGGAEHAVLHLLYARFWHKVLYDLGHVSSREPYRRLVNQGYIQAFAYTDARGSYVPA  710
            D+YVGGAEHAVLHLLYARFWHKVLYDLG V+++EP+++L NQG I + +Y D+RG+ V++
Sbjct  526  DIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVAT  585

Query  711  EEVVERDGRFVYPGPGGEVEVFQEFGKIGKSLKNSISPDEICDDYGADTLRVYEMSMGPL  770
            + V  RDG F     G E+E  Q  +K++KSLKN ++PD++ ++YGADTLRVYEM MGPL
Sbjct  586  DKVEKRDGSFFHVETGEELE--QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPL  643

Query  771  EASRPWATKDVVGAHRFLQRVWRLVVDEQTGETRVLDGPAQELATGTL-RMLHRTIVGVA  829
            +AS +W+  ++ G+++FL+RV RL+   +  E            +G+L ++ + T+ +V+
Sbjct  644  DASIAWSEEGLEGSRKFLDRVYRLITTKEITEE----------NSGALDKVYNETVKAVT  693

Query  830  EDYAALRNNTAAAKLIEYTNHLTKEHREAVPRaaveplvlmlaplaphlaeelwlRVGHT  889
            E+   ++ NTA A+L+ + N   KE++   +  A   + L+ +  +    E      +  
Sbjct  694  EQVDQMKFNTAIAQLMVFVNAANKEDK-LFSDYAKGFVQLIAPFAPHLGEELWQALTASG  752

Query  890  TSLAHGPFPVADPAYLVDDTVEYPVQVNGKVRGRVTVAADADQDTLKAAALADEKVQAFL  949
             S++  P P  D + LV++ VE  VQ++GKV++++ VA D  ++ L+  ALA+EKVQA +
Sbjct  753  ESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEI  812

Query  950  AGANPRKVIVVPGRLVNLVV  969
            AG +  KVI VP +LVN+V+
Sbjct  813  AGKDIIKVIAVPNKLVNIVI  832


 Score =  129 bits (471),  Expect = 1e-30, Method: Compositional matrix adjust.
 Identities = 74/148 (50%), Positives = 99/148 (67%), Gaps = 11/148 (7%)

Query  35   IEGAWQDNWAKLGTFNVPNPVGSLAPPDGSSVPDDKLFVQDMFPYPSGEGLHVGHPLGYI  94
            IE  WQ  WA   TF+            G+  +  K++  DMFPYPSG GLHVGHP GY 
Sbjct  9    IEPKWQAFWADNHTFKT-----------GTDASKPKFYALDMFPYPSGAGLHVGHPEGYT  57

Query  95   ATDVYARYFRMTGRNVLHALGFDAFGLPAEQYAVQTGTHPRTRTEANVVNFRRQLGRLGL  154
            ATD+ +R+ R  G+NVLH++G DAFGLPAEQYA++TG +P   T  N+ NF+RQ+  LG+
Sbjct  58   ATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGF  117

Query  155  GHDSRRSFSTTDVEFYKWTQWIFLQIYN  182
            + D  R  +TTD ++YKWTQWIF ++Y+
Sbjct  118  SYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1582) leuS in NC_017904


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  505 bits (1905),  Expect = 5e-144, Method: Compositional matrix adjust.
 Identities = 347/740 (47%), Positives = 496/740 (68%), Gaps = 57/740 (7%)

Query  232  LVYRADSMVNWCPGLGTVLANEEVTADGRSDRGNFPVFRKRLRQWMMRITAYSdrllddl  291
            L Y A+  VNW   LGT +ANEEV +DG S+RG +PV RK +RQWM++ITAY++RLL+DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  292  elldWPEPVKAMQRNWIGRSTGAKALFAATRADGEAVDIEVFTTRPDTLFGATYLVLAPE  351
            E +DWPE++K MQRNWIG+STGA+  F    +D    D+ VFTTRPDTLFGATY VLAPE
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDK---DFTVFTTRPDTLFGATYAVLAPE  264

Query  352  HDLVDELVAAAWPDGTDPRWTYRAATPGEAVAAYRKAIASKSDLERQE-SKAKTGVFLGS  410
            H LVD + ++                 +EAVA Y++  + KSDL R + +K KTGV  GS
Sbjct  265  HALVDAITTSD---------------QAEAVADYKRQASLKSDLARTDLAKEKTGVWTGS  309

Query  411  YATNPTNGKPVPIFIADYVLAGYGTGAIMAVPGHDQRDWDFAHEFGLPVVEVIAGGDISE  470
            YA NP NGK +P+ IADYVLA+YGTGAIMAVP+HD+RDW+FA +F L ++ V+ GG++ E
Sbjct  310  YAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEE  369

Query  471  AAYAGDGVLVNSGYLDGLDVAAAKEKITARLESEGRGRARIEFKLRDWLFARQRYWGEPF  530
            AA++ DG+ +NS++LDGLD A+A  K+  +LE+EG G   + ++LRDWLF+RQRYWGEP+
Sbjct  370  AAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPI  429

Query  531  PIVYDSDGRAHALDEAALPVELPDVPDYSPVLFdpddadsepsppLAKATEWVHVELDLG  590
            PI+   DG + A+ E+ LP+ LP   D  P         +   +PLA+ T+W++V  +  
Sbjct  430  PIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTDWLEVTRE--  479

Query  591  DGLKPYTRDTNVMPQWAGSSWYELRYTDPHNSERFCAKENEAYWMGPRPAEHGPQDPGGV  650
            DG+K   R+TN MPQWAGSSWY LRY DPHN+E++   E    W+              V
Sbjct  480  DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWL-------------PV  525

Query  651  DLYVGGAEHAVLHLLYARFWHKVLYDLGHVSSREPYRRLVNQGYIQAFAYTDARGSYVPA  710
            D+YVGGAEHAVLHLLYARFWHKVLYDLG V+++EP+++L NQG I + +Y D+RG+ V++
Sbjct  526  DIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVAT  585

Query  711  EEVVERDGRFVYPGPGGEVEVFQEFGKIGKSLKNSISPDEICDDYGADTLRVYEMSMGPL  770
            + V  RDG F     G E+E  Q  +K++KSLKN ++PD++ ++YGADTLRVYEM MGPL
Sbjct  586  DKVEKRDGSFFHVETGEELE--QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPL  643

Query  771  EASRPWATKDVVGAHRFLQRVWRLVVDEQTGETRVLDGPAQELATGTL-RMLHRTIAGVA  829
            +AS +W+  ++ G+++FL+RV RL+   +  E            +G+L ++ + T+ +V+
Sbjct  644  DASIAWSEEGLEGSRKFLDRVYRLITTKEITEE----------NSGALDKVYNETVKAVT  693

Query  830  EDYAALRNNTAAAKLIEYTNHLTKEHREAVPRaaveplvlmlaplaphlaeelwlRLGHT  889
            E+   ++ NTA A+L+ + N   KE++   +  A   + L+ +  +    E      +  
Sbjct  694  EQVDQMKFNTAIAQLMVFVNAANKEDK-LFSDYAKGFVQLIAPFAPHLGEELWQALTASG  752

Query  890  TSLAHGPFPVADPAYLVDDTVEYPVQVNGKVRGRVTVAADADQDTLKAAALADEKVQAFL  949
             S++  P P  D + LV++ VE  VQ++GKV++++ VA D  ++ L+  ALA+EKVQA +
Sbjct  753  ESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEI  812

Query  950  AGTNPRKVIVVPGRLVNLVV  969
            AG +  KVI VP +LVN+V+
Sbjct  813  AGKDIIKVIAVPNKLVNIVI  832


 Score =  129 bits (471),  Expect = 1e-30, Method: Compositional matrix adjust.
 Identities = 74/148 (50%), Positives = 99/148 (67%), Gaps = 11/148 (7%)

Query  35   IEGAWQDNWAKLGTFNVPNPVGSLAPPDGSSVPDDKLFVQDMFPYPSGEGLHVGHPLGYI  94
            IE  WQ  WA   TF+            G+  +  K++  DMFPYPSG GLHVGHP GY 
Sbjct  9    IEPKWQAFWADNHTFKT-----------GTDASKPKFYALDMFPYPSGAGLHVGHPEGYT  57

Query  95   ATDVYARYFRMTGRNVLHALGFDAFGLPAEQYAVQTGTHPRTRTEANVVNFRRQLGRLGL  154
            ATD+ +R+ R  G+NVLH++G DAFGLPAEQYA++TG +P   T  N+ NF+RQ+  LG+
Sbjct  58   ATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGF  117

Query  155  GHDSRRSFSTTDVEFYKWTQWIFLQIYN  182
            + D  R  +TTD ++YKWTQWIF ++Y+
Sbjct  118  SYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1583) PSEBR_a4951 in NC_015379


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  505 bits (1905),  Expect = 5e-144, Method: Compositional matrix adjust.
 Identities = 357/876 (41%), Positives = 554/876 (64%), Gaps = 62/876 (7%)

Query  5    YQPREIEAAAQSFWDEQKSFEVSEQPGKETYYCLSMFPYPSGK-LHMGHVRNYTIGDVIS  63
            Y+   IE+  Q+FW ++ +F  + +++K  +Y L MFPYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMQGKNVLQPMGWDAFGMPAENAAMKNNVAPAKWTYENIAYMKTQLRSLGLAVDWSR  123
            R++R QG NVL+PMGWDAFG+PAE+ AM     PA  T ENIA  K Q+ +LG++ DW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVTTCKPDYYRWEQWLFTRLFEKGVIYRKNGTVNWDPVDQTVLANEQVI-DGRGWRSGAL  182
            EV T  P+YY+W QW+FT+L+EKG+ Y  +  VNW     T +ANE+V+ DG + R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  IEKREIPMYYFKITAYADELLESLDELTGWPEQVKTMQRNWIGKSRGMEVQFPYDVASIG  242
            + ++ +    +KITAYA+ LLE L+E+ +WPE +K MQRNWIGKS G +V F      + 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTF-----KVK  237

Query  243  ETGT-LKVFTTRPDTLMGATYVAVAAEHPLATLAAQNNPELQAFIAECKGGSVAEADVA-  300
            +T+  + VFTTRPDTL GATY  +A+EH+L  + A   ++    +A+ K  +   +D+A 
Sbjct  238  DTDKDFTVFTTRPDTLFGATYAVLAPEHAL--VDAITTSDQAEAVADYKRQASLKSDLAR  295

Query  301  ---TQEKKGLPTSLFVEHPLTGEKLPVWVANYVLMHYGDGAVMAVPAHDERDFEFAHKYN  357
               ++EK G+ T+ +  +P+ G  +PVW+A+YVL  YG GA+MAVPAHDERD EFA ++N
Sbjct  296  TDLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFN  355

Query  358  LPVKAVVRTSAGDQTPEPWQDAYGEHGELINSGEFNGLDFPGAFDAIEVALIKKNLGASR  417
            L + +V+  +  +++      A+ E+G  INS+ ++GLD ++A+  +   L    +G   
Sbjct  356  LDIIPVLEGGNVEEA------AFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNEN  409

Query  418  TQFRLRDWGISRQRYWGCPIPIVHCDTCGDVPVPEDQlpvvlpedvvpdGAG---SPLAR  474
              +RLRDW +SRQRYWG PIPI+H +     +VPE +LP+VLP       +G   SPLA 
Sbjct  410  VTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLAN  469

Query  475  MPEFYECSCPKCGAPAKRETDTMDTFVESSWYYARYASPHYQGGLVEKSAADHWLPVDQY  534
            + +  E +    G  ++RET+TM     SSWYY RY  PH    L +     +WLPVD Y
Sbjct  470  VTDWLEVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIY  528

Query  535  IGGIEHAILHLLYARFFHKLMRDEGLVSSNEPFKNLLTQGMVIAETYYRREANGAYTWFN  594
            +GG EHA+LHLLYARF HK++ D G+V+++EPF++L+ QGM+++ +Y  R++ GA     
Sbjct  529  VGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY--RDSRGA-----  581

Query  595  PSDVELERDSKAKVISAKLIADGLPVEIG-GTEKMAKSKNNGVDPQSMIDQFGADTCRLF  653
                 L    K     + ++      E+  +  KM+KS +N V+P+ +++Q+GADT R++
Sbjct  582  -----LVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVY  636

Query  654  MMFASPPDMSAEWSDSGVEGSHRFLKRVWRLAQA-HVTQGLPGKLDVASLNDEQKAIRRS  712
             MF +P D S  WS+ G+EGS++FL RV RL  + ++T+  +G LD            + 
Sbjct  637  EMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALD------------KV  684

Query  713  IHLAIKQASHDVGQNHKFNTAIAQVMTLMNVLEKAAQG-TEQDRALVHEGLEAVTLLLAP  771
             + ++K  +++V+Q  KFNTAIAQ+M ++N  +K  +  ++  +++V+        L+AP
Sbjct  685  YNETVKAVTEQVDQM-KFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQ--------LIAP  735

Query  772  ITPHISHELWNQLGHADPVID-ARWPVVDETALVQDSLTLVIQVNGKLRGQIEMPaaatr  830
            ++PH+++ELW+ L  ++  I    WP  DE+ LV++ + +V+Q++GK+++++ ++   +R
Sbjct  736  FAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSR  795

Query  831  eeveaaaranenvLRFVDGLTIRKVIVVPGKLVNIV  866
            EE++  A ANE+V   + G  I KVI VP KLVNIV
Sbjct  796  EELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIV  831

1584) leuS in NC_016830


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  505 bits (1903),  Expect = 7e-144, Method: Compositional matrix adjust.
 Identities = 354/874 (41%), Positives = 548/874 (63%), Gaps = 58/874 (6%)

Query  49   YQPREIEAAAQSFWDEQKSFEVSEQPGKETFYCLSMFPYPSGK-LHMGHVRNYTIGDVIS  107
            Y+   IE+  Q+FW ++ +F  + +++K  FY L MFPYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  108  RYQRMQGKNVLQPMGWDAFGMPAENAAMKNNVAPAKWTYENIAYMKTQLRSLGLAVDWSR  167
            R++R QG NVL+PMGWDAFG+PAE+ AM     PA  T ENIA  K Q+ +LG++ DW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  168  EVTTCKPDYYRWEQWLFTRLFEKGVIYRKNGTVNWDPVDQTVLANEQVI-DGRGWRSGAL  226
            EV T  P+YY+W QW+FT+L+EKG+ Y  +  VNW     T +ANE+V+ DG + R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  227  IEKREIPMYYFKITAYADELLESLDELTGWPEQVKTMQRNWIGKSRGMEVQFPYDVASIG  286
            + ++ +    +KITAYA+ LLE L+E+ +WPE +K MQRNWIGKS G +V F       +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTF----KVKD  238

Query  287  EAGTLKVFTTRPDTLMGATYVAVAAEHPLATLAAQNNPELQAFIAECKGGSVAEADVA--  344
                + VFTTRPDTL GATY  +A+EH+L  + A   ++    +A+ K  +   +D+A  
Sbjct  239  TDKDFTVFTTRPDTLFGATYAVLAPEHAL--VDAITTSDQAEAVADYKRQASLKSDLART  296

Query  345  --TQEKKGLATSLFVEHPLTGEKLPVWVANYVLMHYGDGAVMAVPAHDERDFEFAHKYNL  402
              ++EK G+ T+ +  +P+ G  +PVW+A+YVL  YG GA+MAVPAHDERD EFA ++NL
Sbjct  297  DLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNL  356

Query  403  PVKAVVRTSAGDQTPEPWQDAYGEHGELINSGEFNGLDFPGAFDAIEVALIKKNLGASRT  462
             + +V+  +  +++      A+ E+G  INS+ ++GLD ++A+  +   L    +G    
Sbjct  357  DIIPVLEGGNVEEA------AFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENV  410

Query  463  QFRLRDWGISRQRYWGCPIPIVHCDTCGDVPVPEDQlpvvlpedvvpdGAG---SPLARM  519
             +RLRDW +SRQRYWG PIPI+H +     +VPE +LP+VLP       +G   SPLA +
Sbjct  411  TYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANV  470

Query  520  PEFYECSCPKCGAPAKRETDTMDTFVESSWYYARYASPHYQGGLVEKSAADHWLPVDQYI  579
             +  E +    G  ++RET+TM     SSWYY RY  PH    L +     +WLPVD Y+
Sbjct  471  TDWLEVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYV  529

Query  580  GGIEHAILHLLYARFFHKLMRDEGLVSSNEPFKNLLTQGMVIAETYYRREANGAYTWFNP  639
            GG EHA+LHLLYARF HK++ D G+V+++EPF++L+ QGM+++ +Y  R++ GA      
Sbjct  530  GGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY--RDSRGA------  581

Query  640  SDVELERDSKAKVISAKLIADGLPVEIG-GTEKMAKSKNNGVDPQSMIDQFGADTCRLFM  698
                L    K     + ++      E+  +  KM+KS +N V+P+ +++Q+GADT R++ 
Sbjct  582  ----LVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYE  637

Query  699  MFASPPDMSAEWSDSGVEGSHRFLKRVWRLAQAHVSQGLPGKLSVASLNDEQKAIRRSIH  758
            MF +P D S  WS+ G+EGS++FL RV RL  +               +++  A+ +  +
Sbjct  638  MFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTK-----------EITEENSGALDKVYN  686

Query  759  LAIKQASHDVGQNHKFNTAIAQVMTLMNVLEKAAQG-TEQDRALVHEGLEAVTLLLAPIT  817
             ++K  +++V+Q  KFNTAIAQ+M ++N  +K  +  ++  +++V+        L+AP++
Sbjct  687  ETVKAVTEQVDQM-KFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQ--------LIAPFA  737

Query  818  PHISHELWKQLGHADPVID-ARWPVVDETALVQDSLSLVIQVNGKLRGQIEMPaaatree  876
            PH+++ELW+ L  ++  I    WP  DE+ LV++ + +V+Q++GK+++++ ++   +REE
Sbjct  738  PHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREE  797

Query  877  veaaaranenvLRFVDGLTIRKVIVVPGKLVNIV  910
            ++  A ANE+V   + G  I KVI VP KLVNIV
Sbjct  798  LQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIV  831

1585) leuS in NC_020209


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  505 bits (1903),  Expect = 7e-144, Method: Compositional matrix adjust.
 Identities = 356/873 (41%), Positives = 547/873 (63%), Gaps = 56/873 (6%)

Query  5    YQPREIENAAQTFWDAQKSFEVSEQPGKETYYCLSMFPYPSGK-LHMGHVRNYTIGDVIS  63
            Y+   IE   Q+FW  + +F  + +++K  +Y L MFPYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPMGWDAFGMPAENAAMKNNVAPAKWTYENIAYMKTQLRSLGLAVDWSR  123
            R++R  G NVL+PMGWDAFG+PAE+ AM     PA  T ENIA  K Q+ +LG++ DW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVTTCKPDYYRWEQWLFTRLFEKGVIYRKNGTVNWDPVDQTVLANEQVI-DGRGWRSGAV  182
            EV T  P+YY+W QW+FT+L+EKG+ Y  +  VNW     T +ANE+V+ DG + R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  IEKRQIPMYYFKITAYADELLSSLDDLPGWPEQVKTMQRNWIGKSKGMEVQFPYHVESIG  242
            + ++ +    +KITAYA+ LL  L+++ +WPE +K MQRNWIGKS G +V F       +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTF----KVKD  238

Query  243  EAGALKVFTTRPDTLMGATYVAVAAEHPLATQAAQNNPELSAFIAECKGGSVAEADVA--  300
                + VFTTRPDTL GATY  +A+EH+L    A   ++ +  +A+ K  +   +D+A  
Sbjct  239  TDKDFTVFTTRPDTLFGATYAVLAPEHALV--DAITTSDQAEAVADYKRQASLKSDLART  296

Query  301  --TQEKKGLPTGLFVEHPLTGEKLPVWVANYVLMHYGDGAVMAVPAHDERDFEFATKYDL  358
              ++EK G+ TG +  +P+ G  +PVW+A+YVL  YG GA+MAVPAHDERD EFA +++L
Sbjct  297  DLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNL  356

Query  359  PIKSVVRSSSGDTNPAPWQDAYGEHGTLINSGEFDGLDFAGAFDAIEVALIKKNLGASRT  418
             I +V+ +++ +      + A+ E+G  INS+ +DGLD A+A+  +   L    +G    
Sbjct  357  DIIPVLEGGNVE------EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENV  410

Query  419  QFRLRDWGISRQRYWGCPIPIIHCDTCGDVPVPEDQlpvvlpedvvpdGAG---SPLARM  475
             +RLRDW +SRQRYWG PIPIIH +     +VPE +LP+VLP       +G   SPLA +
Sbjct  411  TYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANV  470

Query  476  PEFYECACPKCGAPAKRETDTMDTFVESSWYYARYASPHYQGGLVEKSAADHWLPVDQYI  535
             +  E +    G  ++RET+TM     SSWYY RY  PH    L +     +WLPVD Y+
Sbjct  471  TDWLEVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYV  529

Query  536  GGIEHAILHLLYARFFHKLMRDEGLVSSDEPFKNLLTQGMVIAETYYRREANGAYTWFNP  595
            GG EHA+LHLLYARF HK++ D G+V++ EPF++L+ QGM+++ +Y  R++ GA   + +
Sbjct  530  GGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY--RDSRGA---LVA  584

Query  596  ADVELERDSKAKVISAKLKSDGLPVEIGGTEKMAKSKNNGVDPQSMIDQFGADTCRLFMM  655
            +D    RD+    + +   ++ L     +  KM+KS +N V+P+ +++Q+GADT R++ M
Sbjct  585  TDKVEKRDGSFFHVET---GEELE---QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEM  638

Query  656  FASPPDMSAEWSDSGVEGSHRFLKRVWRLAHA-HVSQGLPGTLNVAALNDEQKAIRRSTH  714
            F +P D S  WS+ G+EGS++FL RV RL  + ++++  +G+L+            +  +
Sbjct  639  FMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALD------------KVYN  686

Query  715  LAIKQAGQDVGQHHKFNTAIAQVMTLMNVLEKAPQATEQDRALIQEGLETVTLLLAPITP  774
             ++K   ++V ++ KFNTAIAQ+M ++N       A++++  L+ +       L+AP++P
Sbjct  687  ETVKAVTEQV-DQMKFNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAP  738

Query  775  HISHELWSRLGHSEAVID-ARWPVQDDSALVQDTLQLVIQVNGKLRGQIDMPasasreev  833
            H+++ELW  L  S   I    WP  D+S LV++ +++V+Q++GK+++++ ++   SREE+
Sbjct  739  HLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREEL  798

Query  834  eaaarvnenVLRFTEGLTIRKVIVVPGKLVNIV  866
            +  A  NE+V     G  I KVI VP KLVNIV
Sbjct  799  QEVALANEKVQAEIAGKDIIKVIAVPNKLVNIV  831

1586) Mycsm_06489 in NC_019966


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  505 bits (1903),  Expect = 9e-144, Method: Compositional matrix adjust.
 Identities = 351/733 (48%), Positives = 489/733 (67%), Gaps = 52/733 (7%)

Query  218  LVYRSDSMVNWCPGLGTVLANEEVTSDGRSERGNFPVFRKRLRQWMMRITAYSdrllddl  277
            L Y ++  VNW   LGT +ANEEV +DG SERG +PV RK +RQWM++ITAY++RLL+DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  278  dlldWPEKVKSMQRNWIGRSTGASVLFGTEAGDIE--VFTTRPDTLFGATYMVLAPEHDL  335
            + +DWPE +K MQRNWIG+STGA+V F     D +  VFTTRPDTLFGATY VLAPEH L
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  336  VDKLTAAAWPAGVDERWTFGAATPAEAVAAYRGAIAAKSDLERQE-NKDKTGVFIGAYAT  394
            VD +T++                 AEAVA Y+   + KSDL R +  K+KTGV  G+YA 
Sbjct  268  VDAITTSD---------------QAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAI  312

Query  395  NPVNGQRIPVFIADYVLIGYGTGAIMAVPGGDQRDWDFATAFGLPIVETVAGGDISQGAY  454
            NPVNG+ +PV IADYVL +YGTGAIMAVP+ D+RDW+FA  F L I+  + GG++ ++A+
Sbjct  313  NPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEAAF  372

Query  455  SGDGEVVNSDYLNGLSVASAKEAITKRLEAAGHGKARVEYKLRDWLFARQRYWGEPFPIV  514
            + DG  +NSD+L+GL  ASA   +  +LEA G G+  V Y+LRDWLF+RQRYWGEP+PI+
Sbjct  373  TEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPII  432

Query  515  YDADGRAHPLPESALPVELPDIPDYAPVQLdpddadsepsppLGKATDWVHVELDLGDGL  574
               DG + ++PES LP+ LP   D  P         +   +PL++ TDW++V  +  DG+
Sbjct  433  HWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTDWLEVTRE--DGV  482

Query  575  KQYSRDTNVMPQWAGSSWYELRYTDPYNSEELCAKENEAYWMGPRPAEHGAKDPGGVDLY  634
            K   R+TN MPQWAGSSWY LRY DP N+E L   E    W+              VD+Y
Sbjct  483  KG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWL-------------PVDIY  528

Query  635  VGGVEHAVLHLLYARFWHKVLYDLGHVSSKEPYRRLVNQGYIQAFAYTDARGAYVPAAEV  694
            VGG EHAVLHLLYARFWHKVLYDLG V++KEP+++L NQG I + +Y D+RGA V++  V
Sbjct  529  VGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKV  588

Query  695  TERGGKFYWTGPDGEIEVNQEFGKIGKSLKNSVSPDEICDNYGADTLRVYEMSMGPLEAS  754
              R+G F+    +   E++Q  +K++KSLKN V+PD++ ++YGADTLRVYEM MGPL+AS
Sbjct  589  EKRDGSFF--HVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  755  RPWATKDVVGAYRFLQRVWRLVVDEQTGTERAAEHEALDDETQKQLHRTIAGVSEDYAAL  814
             +W+  ++ G+ +FL+RV RL+   +   E ++  +       K  + T+ +V+E+   +
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALD-------KVYNETVKAVTEQVDQM  699

Query  815  RNNTAAAKLIEYTNYLTKNGVRSRAALEPLVLMVAPLAPHLAEELWKRL-GHEKSLAHGP  873
            + NTA A+L+ + N   K++         +V ++AP+APHL+EELW+ L +   S++  P
Sbjct  700  KFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVP  759

Query  874  FPVADPQYLVEETIEFPVQVNGKVRSKITVPadadadtleaaaladeKVRAFINGATPKK  933
             P  D   LVE+ +E+ VQ++GKV++K+ V+ D   + L+  ALA+EKV+A I G    K
Sbjct  760  WPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIK  819

Query  934  VIVVAGRLVNIVV  946
            VI V+ +LVNIV+
Sbjct  820  VIAVPNKLVNIVI  832


 Score =  133 bits (487),  Expect = 7e-32, Method: Compositional matrix adjust.
 Identities = 77/148 (53%), Positives = 100/148 (68%), Gaps = 11/148 (7%)

Query  21   IEHAWQQTWAESGTFNVPNPVGSLAPTDGTPVPADKMFVQDMFPYPSGEGLHVGHPLGYI  80
            IE  WQ  WA++ TF+            GT  +  K +  DMFPYPSG GLHVGHP GY 
Sbjct  9    IEPKWQAFWADNHTFKT-----------GTDASKPKFYALDMFPYPSGAGLHVGHPEGYT  57

Query  81   ATDVYARYYRMTGRNVLHALGFDSFGLPAEQYAIQTGTHPRTRTEANIVNFRRQLGRLGF  140
            ATD+ +R+ R  G+NVLH++G D+FGLPAEQYA++TG +P   T  NI NF+RQ+  LGF
Sbjct  58   ATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGF  117

Query  141  GHDARRSFSTTDVDYYKWTQWIFLQIYN  168
            + D  R  +TTD +YYKWTQWIF ++Y+
Sbjct  118  SYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1587) Deipr_0908 in NC_015161


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  504 bits (1900),  Expect = 1e-143, Method: Compositional matrix adjust.
 Identities = 366/850 (44%), Positives = 531/850 (63%), Gaps = 64/850 (7%)

Query  14   YNPHAIEQKWQEAWQASGLYTFDPQAPGEKHYALTMFPYPSGN-LHIGHWYANVAPDAHA  72
            Y+  AIE KWQ  W  +  +  + +A+  K YAL MFPYPSG  LH+GH  +  A D  +
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  73   RWMRMRGHNVLFPMGFDSFGLPAENAAIKRGVNPRSWTYDNIAHMKGQFGRMGTMIDWTR  132
            R  R +GHNVL PMG D+FGLPAE+ A+  G +P   T +NIA+ K Q+  +G   DW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  133  SFATSDPEYYRWNQWFFTQFFKRGLAYKKGGLVNWCPKDQTVLANEQVV-GGACERCGTP  191
               T+DP+YY+W QW+FT+++ +GLAY     VNW     T +ANE+V+ +G+ ER G P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  192  VERRNLSQWYLKITDYADELL-DFSDTDMPERVQLMQTNWIGKSVGAEVTFSTPAGPE--  248
            V R+ + QW LKIT YA+ LL D+ + D PE ++ MQ NWIGKS GA+VTF         
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  249  TVFTTRPDTLLGATFMVLAPEHAKVAELTTDEQRaaveayvaaaGRKTDVERQQ-EGEKT  307
            TVFTTRPDTL+GAT+ VLAPEHA V  +TT +Q  AV  Y   A+ K+D+ R +   EKT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  308  GVFTGSYATHPISGEPLPIWVADYVLVTYGTGSIMAVPAHDERDFAFARAFGLPIKEVIR  367
            GV TGSYA +P++G  +P+W+ADYVL +YGTG+IMAVPAHDERD  FA+ F L I  V+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  368  AEGSEGMGEQPTEPYTGEGLIVNSGEFDGLPGGKASIAKVVERLEAQGIARAKTTYRLRD  427
            +   E        ++T +GL +NS+ +DGL  + ++IAK+VE+LEA+G++  + TYRLRD
Sbjct  364  GGNVEE------AAFTEDGLHINSDFLDGLDKA-SAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  428  WLVGRQRYWGTPIPIIHCEKCGPQPVPDEQLPVRLPDDVEFTP--TGQSPLKLDTEWVKA  485
            WL +RQRYWG PIPIIH E   + +VP+ +LP+ LP   ++ P  TG+SPL   T+W+  
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  486  TCPCCGGPAERDTDTMDTFVDSSWYMYRYLSPDYDGGPFDPAQ--RGLMPVDLYTGGIEH  543
            T    G  + R+T+TM    +SSWY  RY+ P+ +   +   +  +  +PVD+Y GG EH
Sbjct  477  TRE-DGVKGRRETNTMPQWAGSSWYYLRYIDPH-NTEKLADEELLKQWLPVDIYVGGAEH  534

Query  544  AILHLLYSRFWTKVMRDMGLTDQNEPFRRVRNQGMVLG----------------------  581
            A+LHLLY+RFW KV+ D+G+   +EPF+++ NQGM+LG                      
Sbjct  535  AVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGS  594

Query  582  -----------EDGEKMSKSRGNVVDPDDLVAEYGADTVRTYLMFIAPWELGGPWDTKGI  630
                       +   KMSKS  NVV+PDD+V +YGADT+R Y MF++P + + +W   G+
Sbjct  595  FFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGL  654

Query  631  NGPAKWLGRVWSLFFGGQPDGPREDVSEADLRYAVHSTLNKVNGDFERMSFNTIVAALME  690
            +G+ K L+RV  L+     +   E+ +  D  Y  + T++ V  + ++M FNT +A LM 
Sbjct  655  EGSRKFLDRVYRLI--TTKEITEENSGALDKVY--NETVKAVTEQVDQMKFNTAIAQLMV  710

Query  691  LTNVLVRAGRSDLYGSPAWDEALNIFNLMLAPVVPHIAEEVWQGRGGAG-SVHEQSWPQV  749
            + N   + ++  L++  A     + F  ++AP  PH++EE+WQ+  ++G S+   +WP  
Sbjct  711  FVNAANKEDK--LFSDYA-----KGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSY  763

Query  750  DESAAVRDTVTIGVQVTGKMRGQIEISKaasqdealaaaqaNPDIAKHWEGKDIVKVIYV  809
            DES  V + V I VQ+ GK+++++ ++K  S++E    A AN  +  +  GKDI+KVI V
Sbjct  764  DESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAV  823

Query  810  PGRILNIVAK  819
            P +++NIV K
Sbjct  824  PNKLVNIVIK  833

1588) leuS in NC_009142


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  504 bits (1899),  Expect = 2e-143, Method: Compositional matrix adjust.
 Identities = 345/739 (47%), Positives = 503/739 (69%), Gaps = 59/739 (7%)

Query  220  LVYLSEAPVNWAPGLGTVVANEEVTADGLTERGNFPVFRRNLKQWMMRITAYAdrliddl  279
            L Y +E PVNW   LGT +ANEEV +DG +ERG +PV R+ ++QWM++ITAYA+RL++DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  280  drldWPDKIKTMQRNWIGRSQGANVVFPLDGSAGSIEVFTTRPDTLFGVTYLVLAPEHPL  339
            + +DWP+ IK MQRNWIG+S GANV F + ++   + VFTTRPDTLFG TY VLAPEH+L
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  340  VDELTAAQWPQDPDLRWTGGAATPAEAVAQYRRAASMKSDLDRQE-NKEKTGVFTGAWAT  398
            VD +T+++                AEAVA+Y+R AS+KSDL R +  KEKTGV TG+ A 
Sbjct  268  VDAITTSD---------------QAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAI  312

Query  399  NPVNGEQVPVFIADYVLMGYGTGAIMAVPGEDQRDFDFAEAFGLPVVRTVQPSEGFEGGA  458
            NPVNG ++PV IADYVL +YGTGAIMAVP++D+RD +FA  F L ++  ++ ++  E +A
Sbjct  313  NPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNV-EEAA  371

Query  459  YSGEGPRINSANPDVGLDLNGMHLDEAKKTIIEWLESHKHGSGTVQYKLRDWLFARQRYW  518
            ++ +G +INS        L+G++   A   ++EWLE++  G+  V Y+LRDWLF+RQRYW
Sbjct  372  FTEDGLHINSDF------LDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYW  425

Query  519  GEPFPVVYDSDGIPLGLPESELPVVLPEVADYSPRTFDPEDADSRPEPPLAKATEWANVE  578
            GEP+P++   DG + ++PESELP+VLP   D  P         +  E+PLA+ T+W  +E
Sbjct  426  GEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTDW--LE  475

Query  579  LDLGDGLKNYERDTNVMPQWAGSCWYQLRYIDPDNDQAFVDPANERYWMGKRPELHGPDD  638
            +   DG+K   R+TN MPQWAGS WY LRYIDP+N + + D    + W+           
Sbjct  476  VTREDGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWL-----------  523

Query  639  PGGLDLYIGGVEHGVLHLLYSRFWHKVLYDLGHVSSEEPYRRLYNQGYIQAYAYTDSRGV  698
               +D+Y+GG EH+VLHLLY+RFWHKVLYDLG V++ EP+++L+NQG I + +Y DSRG 
Sbjct  524  --PVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGA  581

Query  699  YVPAEEVEERDGKFFF--QGEEVRREYGKMGKSLKNSVSPDEMADAYGADTLRLYEMAMG  756
             V+++ VE RDG FF    GEE+ +  +KM+KSLKN V+PD++ + YGADTLR+YEM MG
Sbjct  582  LVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMG  641

Query  757  PLDASRPWATKDVVGSHRFLQRLWRNVVDENTGELRVTDDEPAIEVLRALHKTIAGVRED  816
            PLDAS +W+  ++ GS++FL+R+ R +   +  E    ++  A++  +  + T+ +V E+
Sbjct  642  PLDASIAWSEEGLEGSRKFLDRVYRLITTKEITE----ENSGALD--KVYNETVKAVTEQ  695

Query  817  YRELRFNTAVAKLIELNNLLTKEYSATGAPRAVVGPLVLMVAPLAPHMAEELWSKLGHDG  876
              +++FNTA+A+L+ + N   KE             +V ++AP+APH++EELW  L   G
Sbjct  696  VDQMKFNTAIAQLMVFVNAANKE---DKLFSDYAKGFVQLIAPFAPHLGEELWQALTASG  752

Query  877  -SLAHGPFPEADEQYLVEDTVEYPIQFNGKVRSRIVVPASAGQdevkaaaladekvvaal  935
             S++  P P  DE  LVE+ VE  +Q++GKV++++VV+   +++E++  ALA+EKV A +
Sbjct  753  ESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEI  812

Query  936  dGREPRKVIVVPGRLVNVV  954
             G++  KVI VP +LVN+V
Sbjct  813  AGKDIIKVIAVPNKLVNIV  831


 Score =  118 bits (430),  Expect = 2e-27, Method: Compositional matrix adjust.
 Identities = 63/120 (53%), Positives = 85/120 (71%), Gaps = 0/120 (0%)

Query  52   GEVSDEKLFVQDMFPYPSGSGLHVGHPLGFIGTDVYARFNRMLGKNVLHTMGFDSFGLPA  111
             + S  K++  DMFPYPSG+GLHVGHP G+ +TD+ +RF+R  G NVLH MG D+FGLPA
Sbjct  27   TDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSRFKRAQGHNVLHPMGWDAFGLPA  86

Query  112  EQYAVQTGTHPRTTTEKNIERYLTQIRRLGLGHDERRRVATTDIPFYRWTQWIFLQIFHS  171
            EQYA++TG +P   T  NI  +  QI  LG++ D  R V TTD  +Y+WTQWIF ++++ 
Sbjct  87   EQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEK  146

1589) ST548_p5866 in NC_020181


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  504 bits (1899),  Expect = 2e-143, Method: Compositional matrix adjust.
 Identities = 357/865 (42%), Positives = 546/865 (64%), Gaps = 46/865 (5%)

Query  5    YRPEEIESKVQLHWDENRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIA  63
            Y    IE+K Q  W +N+TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKKLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EIATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYAdellndldnldHWPDTVKTMQRNWIGRSEGVEISFDVNDYADK  242
            V RK + QW +KITAYA E L +  +  +WP+++K MQRNWIG+S G +++F V+D    
Sbjct  184  VVRKPMRQWMLKITAYA-ERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGCTY--LavaaghplaqqaaannpalaaFI-DECRNTKVAEADMATME  299
            +TV+TTRPDT+ G TY  LA   +   A  ++ +  A+A +  +   ++ +A +D+A  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGVDTGFKAIHPLTGEAIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPV  359
            K GV TG  AI+P+ G  +PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L+I PV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  360  ILAADGSEPDLSEQALTEKGVLFNSGEFSGLDYEAGFNAIADKLAAMGVGERKVNYRLRD  419
            +        ++ E A+TE G+ +NS+ + GLD  +++  + + L A GVG+ +V YRLRD
Sbjct  362  L-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMVTLEDGTVMPTPEDQLPVILP--EDVVMDGIT-SPIKADPEWAKT  476
            W  SRQRYWG PIP++  EDGT  + PE +LP++LP   D+   G   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  T-VNGMPALRETDTFDTFMESSWYYARYTCPQYDKGMLDPNAANYWLPVDIYIGGIEHAI  535
            T  +G+ + RET+T      SSWYY RY  P+    + D +  + WLPVDIY+GG EHA+
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPIDATVER  595
            +HLLY RF HK++ D G+V + EP ++L+ QGM+L+ ++        R+  +++ AT ++
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY--------RDSRGALVAT-DK  587

Query  596  DEKGRIVKAFDPQGRELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPAEMT  655
             EK R    F+ +  E +  + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P + +
Sbjct  588  VEK-RDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  656  LEWQESGVEGANRFLKRVWKLVYEHTSQGPAVALDVASLSEDQQALRRDVHKTIAKVTDD  715
            + W E G+EG+ +FL RV +L+          + +++   E+  AL +  + T+  VT++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLI---------TTKEIT--EENSGALDKVYNETVKAVTEQ  695

Query  716  IGRRQTFNTAIAAVMELMNKLAKAPQESEQDRALMREALLAVVRMLNPFTPHACFTLWQE  775
            +++ + FNTAIA +M ++N        ++++  L  +   + V+++ PF+PH    LWQ 
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  776  LGGEGD-IDNAPWPVADESAMVENTTLVVVQVNGKVRGKITVAVDATEEQVRERAGQEHL  834
            L + G+ I   PWP  DES +VEN   +VVQ++GKV++K+ VA D + E+++E A  ++ 
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  835  VAKYLEGVTVRKVIYVPGKLLNLVV  859
            V   + G  + KVI VP KL+N+V+
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVI  832

1590) leuS in NC_015663


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  504 bits (1899),  Expect = 2e-143, Method: Compositional matrix adjust.
 Identities = 357/865 (42%), Positives = 546/865 (64%), Gaps = 46/865 (5%)

Query  5    YRPEEIESKVQLHWDENRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIA  63
            Y    IE+K Q  W +N+TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKKLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EIATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYAdellndldnldHWPDTVKTMQRNWIGRSEGVEISFDVNDYADK  242
            V RK + QW +KITAYA E L +  +  +WP+++K MQRNWIG+S G +++F V+D    
Sbjct  184  VVRKPMRQWMLKITAYA-ERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGCTY--LavaaghplaqqaaannpalaaFI-DECRNTKVAEADMATME  299
            +TV+TTRPDT+ G TY  LA   +   A  ++ +  A+A +  +   ++ +A +D+A  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGVDTGFKAIHPLTGEAIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPV  359
            K GV TG  AI+P+ G  +PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L+I PV
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  360  ILAADGSEPDLSEQALTEKGVLFNSGEFSGLDYEAGFNAIADKLAAMGVGERKVNYRLRD  419
            +        ++ E A+TE G+ +NS+ + GLD  +++  + + L A GVG+ +V YRLRD
Sbjct  362  L-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  420  WGVSRQRYWGAPIPMVTLEDGTVMPTPEDQLPVILP--EDVVMDGIT-SPIKADPEWAKT  476
            W  SRQRYWG PIP++  EDGT  + PE +LP++LP   D+   G   SP+    +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  477  T-VNGMPALRETDTFDTFMESSWYYARYTCPQYDKGMLDPNAANYWLPVDIYIGGIEHAI  535
            T  +G+ + RET+T      SSWYY RY  P+    + D +  + WLPVDIY+GG EHA+
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  536  MHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPIDATVER  595
            +HLLY RF HK++ D G+V + EP ++L+ QGM+L+ ++        R+  +++ AT ++
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY--------RDSRGALVAT-DK  587

Query  596  DEKGRIVKAFDPQGRELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPAEMT  655
             EK R    F+ +  E +  + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P + +
Sbjct  588  VEK-RDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  656  LEWQESGVEGANRFLKRVWKLVYEHTSQGPAVALDVASLSEDQQALRRDVHKTIAKVTDD  715
            + W E G+EG+ +FL RV +L+          + +++   E+  AL +  + T+  VT++
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLI---------TTKEIT--EENSGALDKVYNETVKAVTEQ  695

Query  716  IGRRQTFNTAIAAVMELMNKLAKAPQEGEQDRALMREALLAVVRMLNPFTPHACFTLWQE  775
            +++ + FNTAIA +M ++N        ++++  L  +   + V+++ PF+PH    LWQ 
Sbjct  696  VDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  776  LGGEGD-IDNAPWPVADESAMVENTTLVVVQVNGKVRGKITVAVDATEEQVRERAGQEHL  834
            L + G+ I   PWP  DES +VEN   +VVQ++GKV++K+ VA D + E+++E A  ++ 
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  835  VAKYLEGVTVRKVIYVPGKLLNLVV  859
            V   + G  + KVI VP KL+N+V+
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIVI  832

1591) leuS in NC_021499


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  504 bits (1899),  Expect = 2e-143, Method: Compositional matrix adjust.
 Identities = 352/879 (41%), Positives = 555/879 (64%), Gaps = 59/879 (6%)

Query  5    YQPREIEAAAQAHWDAHKSFEVSEQPGKDTFYCLSMFPYPSGK-LHMGHVRNYTIGDVIA  63
            Y+   IE+  QA W  + +F  + +++K  FY L MFPYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPMGWDAFGMPAENAAMKNNVAPAKWTYENIDYMKTQLKSLGLAIDWSR  123
            R++R  G NVL+PMGWDAFG+PAE+ AM     PA  T ENI   K Q+++LG++ DW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVTTCKPDYYRWEQWLFTRLFEKGVIYRKNGTVNWDPADQTVLANEQVI-DGRGWRSGAL  182
            EV T  P+YY+W QW+FT+L+EKG+ Y  +  VNW     T +ANE+V+ DG + R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VEKREIPMYYFKITAYADELLSSLDDLPGWPEQVKTMQRNWIGKSRGMEVSFPYDQASIG  242
            V ++ +    +KITAYA+ LL  L+++ +WPE +K MQRNWIGKS G +V+F   ++   
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTD--  240

Query  243  QAGALKVFTTRPDTLLGATYVAVAAEHPLATLAVQQLPADKAAELQAFIDECKRGGVAEA  302
                + VFTTRPDTL+GATY  +A+EH+L    V+ + +   AE    + + KR +   +
Sbjct  241  --KDFTVFTTRPDTLFGATYAVLAPEHAL----VDAITTSDQAEA---VADYKRQASLKS  291

Query  303  DIA----TQEKKGLPTPLFVVHPLTGDKLPVWVANYVLMNYGEGAVMAVPAHDERDFAFA  358
            D+A    ++EK G+ T  + ++P+ G  +PVW+A+YVL +YG GA+MAVPAHDERD  FA
Sbjct  292  DLARTDLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFA  351

Query  359  HKYDLPVKPVIRTAAGDETPAPWQDAYGEHGQLINSGAFDGLDFQGAFDAIEVALQKKGL  418
             +++L + PV+  +  +E+      A+ E+G  INS+ +DGLD  +A+  +   L+  G+
Sbjct  352  KQFNLDIIPVLEGGNVEEA------AFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGV  405

Query  419  GQARTQFRLRDWGISRQRYWGCPIPIIHCPSCGDVPVPEDQlpvvlpedvvpdGAG---S  475
            G+    +RLRDW +SRQRYWG PIPIIH       +VPE +LP+VLP       +G   S
Sbjct  406  GNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGES  465

Query  476  PLAKMPEFYNCTCPKCGTAAKRETDTMDTFVESSWYFARYASPNYEQGMVDPVAANHWLP  535
            PLA++ +  + T    G  ++RET+TM     SSWY+ RY  P+  + + D    ++WLP
Sbjct  466  PLANVTDWLEVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLP  524

Query  536  VDQYIGGIEHAILHLLYARFFHKLMRDEGLVSSDEPFKNLLTQGMVVAETYYRTASNGGK  595
            VD Y+GG EHA+LHLLYARF HK++ D G+V++ EPF++L+ QGM+++ + YR +  +  
Sbjct  525  VDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS-YRDSRGA--  581

Query  596  DWFNPADVEVERDAKAKVIGARLMTDGQPVEIGGTEKMSKSKNNGVDPQAMIDAYGADTC  655
              + ++D    RD+    + +     G+ +E  +  KMSKS +N V+P+ +++ YGADT 
Sbjct  582  --LVATDKVEKRDGSFFHVET-----GEELE-QAPAKMSKSLKNVVNPDDVVEQYGADTL  633

Query  656  RLFMMFASPPDMSLEWSDSGVEGASRFLRRVWRLaqahvaagavaELDRSALNDEQKAVH  715
            R++ MF +P D S+ WS+ G+EG+ +FL RV RL              +   +++  A++
Sbjct  634  RVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLIT-----------TKEITEENSGALD  682

Query  716  RSIHLAIRQASQDVGQHHKFNTAIAAVMTLMNVLEKAPQASAEDRALLQEGLEAVALLLA  775
            +  + +++  +++V ++ KFNTAIA +M ++N  +K       +  L+ +   +   L+A
Sbjct  683  KVYNETVKAVTEQV-DQMKFNTAIAQLMVFVNAANK-------EDKLFSDYAKGFVQLIA  734

Query  776  PITPHISHVLWNEL-GHADAIIDAAWPTVDEAAlvqdslqlvvqvNGKLRGHIEVPADAS  834
            P++PH+++ LW+ L + +++I   +WP+ DE+ LV++ +++VVQ++GK+++ + V+ D S
Sbjct  735  PFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLS  794

Query  835  REAVEATARANENVLRFTDGLTIRKVIVVPGKLVNIVAN  873
            RE ++  A ANE+V     G  I KVI VP KLVNIV +
Sbjct  795  REELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

1592) leuS in NC_012880


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  504 bits (1902),  Expect = 9e-144, Method: Compositional matrix adjust.
 Identities = 353/866 (41%), Positives = 554/866 (64%), Gaps = 48/866 (5%)

Query  5    YRPEDIEAHVQLHWQEKQTFKVTEEPGKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIS  63
            Y    IE+  Q  W +++TFK   +++K K+Y L M+PYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYANIEYMKNQLKVLGFGYDWDR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T  NI   K Q++ LGF+YDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVTTCRPEYYRWEQWFFTKLYEKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            EV T  P+YY+W QW+FTKLYEKGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFVKITAYAEELLNDLDTLESWPEQVKTMQRNWIGRSEGVEItfdvtdstdt  242
            V RK + QW +KITAYAE LL+DL+ ++ WPE +K MQRNWIG+S G ++TF V D+   
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  ltvyttRPDTFIgatyvavaaahplalgaaannpalsaFVDECRNTKVAEADMA----TM  298
            +TV+TTRPDT++GATY  +A+ H+L  + ++++ A +  V + +      +D+A    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEA--VADYKRQASLKSDLARTDLAK  300

Query  299  EKKGIATGLFVVHPLTGEKLPVWAANFVLMDYGTGAVMAVPGHDQRDWEFATKYNLPIKP  358
            EK G+ TG + ++P+ G  +PVW A++VL  YGTGA+MAVP+HD+RDWEFA ++NL I P
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VILNADGSEPDLSAQAMTEKGQLFNSGEFSGLDHAAGFNAIADKLVSLGVGARKVNYRLR  418
            V+  ++  E+ ++ +++  ++++++     GLD A+++  + + L + GVG  +V YRLR
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLD-----GLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  419  DWGVSRQRYWGAPIPMVTLEDGTVMPTPEDQLPVILP--EDVTMDGIT-SPIKADPQWAK  475
            DW  SRQRYWG PIP++  EDGT  + PE +LP++LP   D+   G   SP+    +W  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  476  TT-VNGQPALRETDTFDTFMESSWYYARYTCPQYDQGMLDPAAANYWLPVDQYVGGIEHA  534
             T  +G  + RET+T      SSWYY RY  P+  + + D    + WLPVD YVGG EHA
Sbjct  476  VTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  535  IMHLMYFRFFHKLMRDAGLVNSNEPAKRLLCQGMVLADAFFYTGDNGERIWVSPVDVTVE  594
            ++HL+Y RF HK++ D G+V ++EP ++L+ QGM+L+ +  Y +  G         V+ +
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS--YRDSRGAL-------VATD  586

Query  595  RDDKGRIVKAFDQEGRELVYAGMSKMSKSKNNGIDPQVMVEKYGADTVRLFMMFASPAEM  654
            + +K R    F+ E  E +  + +KMSKS +N ++P+ +VE+YGADT+R++ MF +P + 
Sbjct  587  KVEK-RDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  655  TLEWQESGVEGANRFLKRVWKQVYDHTAKGSTQPLNIAELTDDQKALRRDLHKTIAKVTD  714
            ++ W E G+EG+ +FL RV + +   T+K  T+        ++  AL +  + T+  VT+
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLI---TTKEITE--------ENSGALDKVYNETVKAVTE  694

Query  715  DIGRRQTFNTAIAAIMELMNKLAKAPQGAEQDRALTQETLLAVVRMLYPFTPHVSFTLWH  774
            ++++ + FNTAIA +M ++N       +A+++  L  +   + V+++ PF+PH++  LW+
Sbjct  695  QVDQMK-FNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  775  ELQGEGD-IDRAPWPVADEQAMVEDSRLVVVQVNGKVRGKITVAADATEQQVRDRAAQEP  833
             L + G+ I   PWP  DE  +VE+   +VVQ++GKV++K+ VA D + +++++ A  + 
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  834  LVAKYLDGVTVRKVIFVPGKLLNLVV  859
             V   + G  + KVI VP KL+N+V+
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIVI  832

1593) leuS in NC_021505


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  504 bits (1902),  Expect = 9e-144, Method: Compositional matrix adjust.
 Identities = 361/884 (41%), Positives = 554/884 (63%), Gaps = 74/884 (8%)

Query  5    YTPRDIEAAAQNFWDEQQSFAVTEQPGKDTYYCLSMFPYPSGK-LHMGHVRNYTIGDVIA  63
            Y    IE+  Q FW ++++F    +++K  +Y L MFPYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPMGWDAFGMPAENAAMKNNVAPAKWTYENIDYMKTQLKSLGLAIDWAR  123
            R++R  G NVL+PMGWDAFG+PAE+ AM     PA  T ENI   K Q+++LG++ DW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVTTCKPDYYRWEQWLFTRLFEKGIIYRKNGTVNWDPADQTVLANEQVI-DGRGWRSGAL  182
            EV T  P+YY+W QW+FT+L+EKG+ Y  +  VNW     T +ANE+V+ DG + R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  IEKREIPMYYFRITDYADELLESLDELPGWPEQVKTMQRNWIGKSRGMEVQFPYDQASIG  242
            + ++ +    ++IT YA+ LLE L+E+ +WPE +K MQRNWIGKS G +V F   ++   
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDT---  239

Query  243  HEGTLKVFTTRPDTLMGATYVAVAAEHPLATQAAQGNPALQAFIDECKSGSVAEADMA--  300
             +  + VFTTRPDTL GATY  +A+EH+L    + ++ A    + + K  +   +D+A  
Sbjct  240  -DKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQA--EAVADYKRQASLKSDLART  296

Query  301  --TQEKKGMATSLLVEHPLTGEKLPVWVANYVLMHYGDGAVMAVPAHDERDFEFARKYNL  358
              ++EK G+ T+    +P+ G  +PVW+A+YVL  YG GA+MAVPAHDERD EFA+++NL
Sbjct  297  DLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNL  356

Query  359  PVKAVVRTSEGDDVGNEWLAAYNEHGQLINSGEFDGLDFAGAFDAIETALIRKELGKSRT  418
             + +V+  ++ ++      AA+ E+G  INS+ +DGLD A+A+  +   L    +G+   
Sbjct  357  DIIPVLEGGNVEE------AAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENV  410

Query  419  QFRLRDWGISRQRYWGCPIPIIHCPSCGDVPVPEDQLPVTLP--ENVVPDGAG-SPLARM  475
             +RLRDW +SRQRYWG PIPIIH       +VPE +LP+ LP   ++ P G+G SPLA +
Sbjct  411  TYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANV  470

Query  476  PEFYECTCPKCGTAAKRETDTMDTFVESSWYFARYASPNYDKGLVDPKAANHWLPVDQYI  535
             +  E T    G  ++RET+TM     SSWY+ RY  P+    L D    ++WLPVD Y+
Sbjct  471  TDWLEVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYV  529

Query  536  GGIEHAILHLLYARFFHKLMRDEGLVTSNEPFKNLLTQGMVVAETYYRVASNGGKDWFNP  595
            GG EHA+LHLLYARF HK++ D G+V ++EPF++L+ QGM+++ +Y              
Sbjct  530  GGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY--------------  575

Query  596  ADVEIERDAKAKIIGARL--KTDG--LPVEIG-----GTEKMSKSKNNGVDPQSMIEAYG  646
                  RD+++ ++++    K DG  + VE G     +  KMSKS +N V+P+ ++E YG
Sbjct  576  ------RDSRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYG  629

Query  647  ADTCRLFMMFASPPDMSLEWSDSGVEGASRFLRRVWRLAQA-HVSQGLPGKLDVAALDDA  705
            ADT R++ MF +P D S+ WS+ G+EG+ +FL RV RL  + ++++  +G LD       
Sbjct  630  ADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALD-------  682

Query  706  QKVIRRAIHAAIKQASNDVGQFHKFNTAIAQVMTVMNVLEKAPQASEQDRALLHEGLEAV  765
                 +  + ++K  +++V+Q  KFNTAIAQ+M  +N       A++++  L+ +   + 
Sbjct  683  -----KVYNETVKAVTEQVDQM-KFNTAIAQLMVFVN-------AANKEDKLFSDYAKGF  729

Query  766  TLLLSPITPHISHALWQHLGHTGSVID-AAWPSVDEQAlvqdtvtlvvqvNGKLRGQVEM  824
              L++P++PH+++ LWQ L  +G  I   +WPS DE  LV++ V +VVQ++GK+++++ +
Sbjct  730  VQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVV  789

Query  825  PaaasreeveaaarsnenvLRFIDGLTIRKVIVVPGKLVNIVAN  868
            +   SREE++  A +NE+V   I G  I KVI VP KLVNIV +
Sbjct  790  AKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

1594) Rxyl_3202 in NC_008148


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  503 bits (1897),  Expect = 2e-143, Method: Compositional matrix adjust.
 Identities = 364/841 (44%), Positives = 542/841 (65%), Gaps = 50/841 (5%)

Query  14   YDPRAIEERWQRRWAETGLYKTDEDPSKPKHYALTMLPYPSG-DLHVGHWYAMTPSDTRA  72
            YD  AIE +WQ  WA+   +KT+ D+SKPK YAL M+PYPSG +LHVGH  + T++D  +
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  73   RFMRMRGYRVFFPIGFDAFGLPAENAAIKRGIHPRDWTYSNIERMRGQLRQMGTMFDFDA  132
            RF R +G  V+ P+G DAFGLPAE+ A+  G +P + T  NI   + Q+  +G  +D D 
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  133  EVVTCDPEYYRWNQWFFLKFYEKGLAYREKAPVDWCPSCNTTLAREQVVGPDRRCERCDT  192
            EV T DP+YY+W QW+F K+YEKGLAY    PV+W     T++A E+V+ PD   ER + 
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVL-PDGTSERGGY  182

Query  193  PVIKRNLAQWLFKITDYAEELL-DFSEIEWPERVKALQRNWIGRSEGAEIEFEIEGYG-G  250
            PV+++ + QW++KIT YAE LL D+ E++WPE +K +QRNWIG+S GA++ F + + + +
Sbjct  183  PVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  251  VTVFTTRPDTLFGATFFVVAPEHPAVESITTPERGEEVRAYVERAARMSEIDRADVTREK  310
             TVFTTRPDTLFGAT+ V+APEH+ V++ITT++++E V  Y  +A+  S++ R+D+++EK
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEK  302

Query  311  TGVFTGAYAVNPANGERIPVYVADYVLMGYGTGAIMAVPAHDERDFEFAKKHGIEIRTVI  370
            TGV TG+YA+NP NG  +PV +ADYVL +YGTGAIMAVPAHDERD EFAK+  ++I  V+
Sbjct  303  TGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL  362

Query  371  APPDWDGSPLERAYVGEGQMVNSGPFDGTPSAEGREKVTGWLRERGVGRPAVNYRLRDWL  430
                 +G+  E A+  +G  +NS+ +DG   A +  K+  WL   GVG   V YRLRDWL
Sbjct  363  E----GGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWL  418

Query  431  ISRQRYWGTPIPIVYCERCGTvpvpeedlpvllpedAEFMPTGESPLKFNDEFRKTECPR  490
            +SRQRYWG PIPI+  E   + +VPE +LP++LP   ++ P+G +   + +     E  R
Sbjct  419  FSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTR  478

Query  491  CGG-PAERETDTMDTFVDSSWYQYRYLSPHYEEGPFDPERGSRWLPVDQYTGGIEHATMH  549
             +G  + RET+TM    +SSWY  RY+ PH  E   D E   +WLPVD Y GG EHA +H
Sbjct  479  EDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLH  538

Query  550  LLYTRFFTKVMRDLGLVDFDEPMLRLFNQGVILGP-------------------------  584
            LLY+RF  KV+ DLG+V   EP  +LFNQG+ILG                          
Sbjct  539  LLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHV  598

Query  585  --------DGNRMSKSRGNVVNPQEYVDRYGSDVLRCYLMFigpwdeggpwdpggiegVA  636
                       +MSKS  NVVNP++ V++YG+D LR Y MF+GP D + +W   G+EG  
Sbjct  599  ETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSR  658

Query  637  RWLRRAFTLVAGGDVSEAEADPGELSRRTHRLVKRVTEYLEGFRFNTAIAALMEHTNYLL  696
            + L R + L++  +++  E ++G L +  +  VK VTE ++  +FNTAIA LM     ++
Sbjct  659  KFLDRVYRLITTKEIT--EENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLM-----VF  711

Query  697  AVKGEVGEEEWREAMRSFLLVLAPFAPHHAEEMWEIL-GEEYSVHEQGWPSWDeelvree  755
               ++  +    +  ++F+ ++APFAPH +EE+W+ L +   S+    WPS DE  + E+
Sbjct  712  VNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVEN  771

Query  756  tvtlvvQVNGKLRDRVEAPAGVDEGRARELALSSERVRAHVEGRELRKTVYVPGRLINLV  815
             V +VVQ++GK++ ++  + ++     +E+AL++E+V+A++ G+++ K + VP +L+N+V
Sbjct  772  DVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIV  831

Query  816  V  816
            +
Sbjct  832  I  832

1595) OCO_00480 in NC_016947


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  503 bits (1897),  Expect = 3e-143, Method: Compositional matrix adjust.
 Identities = 348/742 (47%), Positives = 502/742 (68%), Gaps = 61/742 (8%)

Query  232  LVYRADSMVNWCPGLGTVLANEEVTADGRSDRGNFPVFRKRLRQWMMRITAYSdrllddl  291
            L Y A+  VNW   LGT +ANEEV +DG S+RG +PV RK +RQWM++ITAY++RLL+DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  292  elldWPEPVKAMQRNWIGRSTGAKALFAATKADGEAVDIEVFTTRPDTLFGATYLVLAPE  351
            E +DWPE++K MQRNWIG+STGA+  F    +D    D+ VFTTRPDTLFGATY VLAPE
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDK---DFTVFTTRPDTLFGATYAVLAPE  264

Query  352  HGLVDELVAAAWPDGTDPRWTYRAATPGEAVDAYRKAIASKSDLERQE-SKAKTGVFLGS  410
            H+LVD + ++                 +EAV  Y++  + KSDL R + +K KTGV  GS
Sbjct  265  HALVDAITTSD---------------QAEAVADYKRQASLKSDLARTDLAKEKTGVWTGS  309

Query  411  YATNPTNGKPVPIFIADYVLAGYGTGAIMAVPGHDQRDWDFAHEFGLPIVEVIAGGDISE  470
            YA NP NGK +P+ IADYVLA+YGTGAIMAVP+HD+RDW+FA +F L I+ V+ GG++ E
Sbjct  310  YAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEE  369

Query  471  AAYAGDGVLVNSGYLDGLDVAAAKEKITARLESEGRGQARIEFKLRDWLFARQRYWGEPF  530
            AA++ DG+ +NS++LDGLD A+A  K+  +LE+EG G+  + ++LRDWLF+RQRYWGEP+
Sbjct  370  AAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPI  429

Query  531  PIVYDADGRAHALDEAALPVELPDVPDYSPVLFdpddadsepsppLAKATEWVHVELDLG  590
            PI+   DG + A+ E+ LP+ LP   D  P         +   +PLA+ T+W++V  +  
Sbjct  430  PIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTDWLEVTRE--  479

Query  591  DGLKPYTRDTNVMPQWAGSSWYELRYTDPHNSERFCAKENEAYWMGPRPAEHGPQDPGGV  650
            DG+K   R+TN MPQWAGSSWY LRY DPHN+E++   E    W+              V
Sbjct  480  DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWL-------------PV  525

Query  651  DLYVGGAEHAVLHLLYARFWHKVLYDLGHVSSREPYRRLVNQGYIQAFAYTDARGSYVPA  710
            D+YVGGAEHAVLHLLYARFWHKVLYDLG V+++EP+++L NQG I + +Y D+RG+ V++
Sbjct  526  DIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVAT  585

Query  711  EEVVERDGRFVYPGPGGEVEVFQEFGKIGKSLKNSISPDEICDDYGADTLRVYEMSMGPL  770
            + V  RDG F     G E+E  Q  +K++KSLKN ++PD++ ++YGADTLRVYEM MGPL
Sbjct  586  DKVEKRDGSFFHVETGEELE--QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPL  643

Query  771  EASRPWATKDVVGAHRFLQRVWRLVVDEQTGETRVLDGPAQELATGTL-RMLHRTIAGVA  829
            +AS +W+  ++ G+++FL+RV RL+   +  E            +G+L ++ + T+ +V+
Sbjct  644  DASIAWSEEGLEGSRKFLDRVYRLITTKEITEE----------NSGALDKVYNETVKAVT  693

Query  830  EDYAALRNNTAAAKLIEYTNHLTKEHR--EEVPRaaveplvlmlaplaphlaeelwlRLG  887
            E+   ++ NTA A+L+ + N   KE++   + +++ V+ +    + L+ +L + L    +
Sbjct  694  EQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALT---A  750

Query  888  HTTSLAHGPFPVADPAYLVDDTVEYPVQVNGKVRGRVTVAADADQDTLKAAALADEKVQA  947
               S++  P P  D + LV++ VE  VQ++GKV++++ VA D  ++ L+  ALA+EKVQA
Sbjct  751  SGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQA  810

Query  948  FLAGAYPRKVIVVPGRLVNLVV  969
             +AG    KVI VP +LVN+V+
Sbjct  811  EIAGKDIIKVIAVPNKLVNIVI  832


 Score =  128 bits (470),  Expect = 1e-30, Method: Compositional matrix adjust.
 Identities = 74/148 (50%), Positives = 99/148 (67%), Gaps = 11/148 (7%)

Query  35   IEGAWQDNWAKLGTFNVPNPVGSLAPPDGSSVPDDKLFVQDMFPYPSGEGLHVGHPLGYI  94
            IE  WQ  WA   TF+            G+  +  K++  DMFPYPSG GLHVGHP GY 
Sbjct  9    IEPKWQAFWADNHTFKT-----------GTDASKPKFYALDMFPYPSGAGLHVGHPEGYT  57

Query  95   ATDVYARYFRMTGRNVLHALGFDAFGLPAEQYAVQTGTHPRTRTEANVVNFRRQLGRLGL  154
            ATD+ +R+ R  G+NVLH++G DAFGLPAEQYA++TG +P   T  N+ NF+RQ+  LG+
Sbjct  58   ATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGF  117

Query  155  GHDSRRSFSTTDVEFYKWTQWIFLQIYN  182
            + D  R  +TTD ++YKWTQWIF ++Y+
Sbjct  118  SYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1596) leuS in NC_016887


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  503 bits (1897),  Expect = 3e-143, Method: Compositional matrix adjust.
 Identities = 345/735 (47%), Positives = 498/735 (68%), Gaps = 55/735 (7%)

Query  226  LVYQTDSVVNWCPGLGTVLSNEEVTAEGRSERGNFPVFRKRLWQWMMRITAYAdrlvddl  285
            L Y+++  VNW   LGT ++NEEV ++G SERG +PV RK ++QWM++ITAYA+RL++DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  286  drldWPENVKAMQRNWIGRSRGAQVRFAADG--HELEVFTTRPDTLFGATYVVLAPEHEL  343
            + +DWPE++K MQRNWIG+S GA+V F   +   ++ VFTTRPDTLFGATY VLAPEH L
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  344  ADQLTAAAWPEGVDPRWTNGGAATPTDALADYRKAIAAKSDLERQE-NKDKTGVFLGSYA  402
             D +T++                  ++A+ADY++  + KSDL R +  K+KTGV  GSYA
Sbjct  268  VDAITTSD----------------QAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYA  311

Query  403  TNPVNGAQVPIFVADYVLSGYGTGAIMAVPGHDQRDWEFATAFGLPIVEVISGGDVTEAA  462
             NPVNG ++P+ +ADYVL++YGTGAIMAVP+HD+RDWEFA  F L I+ V+ GG+V EAA
Sbjct  312  INPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEAA  371

Query  463  YAGDGTLVNSDYLDGLSVEEAKATVIGRLEADGHGTGTVQYKLRDWLFARQRYWGEPFPI  522
            ++ DG  +NSD+LDGL    A A ++ +LEA+G G   V Y+LRDWLF+RQRYWGEP+PI
Sbjct  372  FTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPI  431

Query  523  VYDEDGAPHALPESMLPVQLPELDDFAPVTFdpddadsepsppLAKATDWVHVELDLGDG  582
            +  EDG++ A+PES LP+ LP   D+ P             +PLA+ TDW++V  +  DG
Sbjct  432  IHWEDGTSTAVPESELPLVLPVTKDIRPSG--------TGESPLANVTDWLEVTRE--DG  481

Query  583  LKKYRRDTNVMPNWAGSSWYQLRYADPTNSETFCAKENEQYWLGPRAEGHGPDDPGGVDL  642
            +K  RR+TN MP+WAGSSWY LRY DP N+E +   E  + WL              VD+
Sbjct  482  VKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWL-------------PVDI  527

Query  643  YVGGVEHAVLHLLYARFWQKVLFDLGDVSGCEPYRRLFNQGYIQAYAYTDSRGAYVPAAE  702
            YVGG EHAVLHLLYARFW+KVL+DLG V+  EP+++LFNQG I + +Y DSRGA V++  
Sbjct  528  YVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDK  587

Query  703  VVERDGKFFWTDASGTEVEVNQEYGKIGKSLKNAISPDEICDQYGADTFRFYEMSMGPLD  762
            V  RDG FF  +++    E++Q  +K++KSLKN ++PD++ +QYGADT+R YEM MGPLD
Sbjct  588  VEKRDGSFFHVETGE---ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLD  644

Query  763  TSRPWATKDVVGAHRFLQRVWRLVVDEETGALRVTDEQPSDETLRLLHKTIAGVDEDLAA  822
            +S +W+  ++ G+++FL+RV RL+   E        E+ S+   ++ + T+ +V E++  
Sbjct  645  ASIAWSEEGLEGSRKFLDRVYRLITTKEIT------EENSGALDKVYNETVKAVTEQVDQ  698

Query  823  LRDNTAGAKLIELTNHLTKAYPDGAPRSVVEPLVLMLAPLAPHITEELWERLGHTT-ALA  881
            ++ NTA A+L+ + N   K   D         +V ++AP+APH+ EELW+ L  +  +++
Sbjct  699  MKFNTAIAQLMVFVNAANKE--DKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESIS  756

Query  882  HGPFPVADPALLVDESVEYPIQVKGKVRSRIQVPadadqasieaaaladekiaalleGNA  941
              P P  D + LV++ VE  +Q+KGKV++++ V+ D  +  ++  ALA+EK+ A + G+ 
Sbjct  757  YVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKD  816

Query  942  PRKIIVVPGRMVNIV  956
              K+I VP ++VNIV
Sbjct  817  IIKVIAVPNKLVNIV  831


 Score =  121 bits (444),  Expect = 2e-28, Method: Compositional matrix adjust.
 Identities = 76/144 (53%), Positives = 106/144 (74%), Gaps = 7/144 (4%)

Query  33   IERRWQQTWAERGTFHAPNPVGPLAGPTPPDKLFVQDMFPYPSGAGLHVGHPLGYIATDV  92
            IE +WQ  WA+  TF +       +  ++  K++  DMFPYPSGAGLHVGHP GY ATD+
Sbjct  9    IEPKWQAFWADNHTFKT-------GTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDI  61

Query  93   FARYHRMHGRNVLHALGYDAFGLPAEQYAVQTGAHPRDTTESNIATMQrqldrlglghdr  152
            ++R+ R +G+NVLH++G DAFGLPAEQYA++TG +P + T  NIA  +RQ++ LG++ D+
Sbjct  62   LSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDW  121

Query  153  rrSFATTDPEYYKWTQWIFLRIYN  176
             R   TTDP+YYKWTQWIF ++Y+
Sbjct  122  DREVNTTDPNYYKWTQWIFTKLYE  145

1597) leuS in NC_012669


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  502 bits (1895),  Expect = 3e-143, Method: Compositional matrix adjust.
 Identities = 338/742 (46%), Positives = 484/742 (66%), Gaps = 63/742 (8%)

Query  230  LAYISNSPVNWAPGLGTVLSNEEVTADGRSERGNFPVFQRNLRQWMLRITAYADRLVDDL  289
            LAY ++ PVNW   LGT ++NEEV +DG SERG +PV ++ +RQWML+ITAYA+RL++DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  290  ELIEWPEKVKTMQRNWIGRSSGAQVRF-VTDAG-DLSVFTTRPDTLFGATFVAVAPEHPL  347
            E ++WPE +K MQRNWIG+S+GA+V F V D++ D++VFTTRPDTLFGAT+  +APEH+L
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  348  LDALASEQWPEGTSEAWTGAAASPREAVTAYRRAASTKTELDRQTEGRDKTGVFTGAFAT  407
            +DA+++               +   EAV+ Y+R AS K++L R   +++KTGV TG++A 
Sbjct  268  VDAITT---------------SDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAI  312

Query  408  NPVTGARVPVFVADYVLMGYGTGAIMAVPGQDERDWEFATRFGLPIVRTVAPPEGWEGEA  467
            NPV G  +PV +ADYVL +YGTGAIMAVP++DERDWEFA +F L I+  +   +  E  A
Sbjct  313  NPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNV-EEAA  371

Query  468  YPGEGPAINSANDEISLDGLGVVEAKAAIIAWLEAKGLGTGTVTYRLRDWLFSRQRYWGE  527
            +  +G  INS      LDGL+   A A ++ WLEA G+G   VTYRLRDWLFSRQRYWGE
Sbjct  372  FTEDGLHINSD----FLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGE  427

Query  528  PFPVVFDDDGRAHTLPDEMLPVELPDVPDYAPRTFDPQDADSEPEPPLARLPEWVDVELD  587
            P+P++  +DG + ++P+  LP+ LP   D  P         +  E+PLA + +W++V  +
Sbjct  428  PIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTDWLEVTRE  479

Query  588  LGDGVRRYRRETNTMPNWAGSCWYELRYLDPHDEKALVDPDIERYWMGPGAERPGGDPTD  647
              DGV+  RRETNTMP+WAGS WY LRY+DPH+   L D ++ + W+             
Sbjct  480  --DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWL-------------  523

Query  648  VAGGADLYVGGVEHAVLHLLYARFWHKVLYDLGHTASREPFHKLFNQGYIQAYAYADARG  707
                 D+YVGG EHAVLHLLYARFWHKVLYDLG  +++EPF+KLFNQG I + +Y D+RG
Sbjct  524  ---PVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRG  580

Query  708  VYVPADEVHEEPG--LDGETTYTWRGEPVVREYGKMGKSLKNMVTPDDMYAAYGADTFRV  765
              V++D V+   G  ++ ET     GE + +  +KM+KSLKN+V PDD+   YGADT+RV
Sbjct  581  ALVATDKVEKRDGSFFHVET-----GEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRV  635

Query  766  YEMSMGPLDQSRAWETRAVVGAQRFLQRLWRNVVDETSGAvvvveePADDATRRLVARTI  825
            YEM MGPLD S AW   ++ G+++FL+R+ R +                +A  ++   T+
Sbjct  636  YEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITE------ENSGALDKVYNETV  689

Query  826  ADVRTEYAAMRPNTAIAKLIALNNHLTTLAAVPREAVEPLVLMVAPVAPHIAEELWARLG  885
              V  +   M+ NTAIA+L+ + N       +  +    +V ++AP APH++EELW  L 
Sbjct  690  KAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALT  749

Query  886  HPA-SLAHEPFPTADPALLVEETVTCVVQVAGKVRDRIEVPPAIGeaelrelalaTAGVQ  944
             ++ S++  P P+ D + LVE+ V  VVQ+ GKV+ ++ V+  ++  EL+E+ALA   VQ
Sbjct  750  ASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQ  809

Query  945  RALDGRGVRTVIVRAPRLVNVV  966
              + G+++  VI  + +LVN+V
Sbjct  810  AEIAGKDIIKVIAVPNKLVNIV  831


 Score =  126 bits (460),  Expect = 1e-29, Method: Compositional matrix adjust.
 Identities = 82/154 (54%), Positives = 108/154 (71%), Gaps = 9/154 (5%)

Query  30   IELAWQDRWASEGTFHAPNPSGDLVGDAAAEKFYVLDMFPYPSGKGLHVGHPLGYIATDV  89
            IE  WQ  WA + TF +         DA+  KFY LDMFPYPSG GLHVGHP GY ATD+
Sbjct  9    IEPKWQAFWADNHTFKTGT-------DASKPKFYALDMFPYPSGAGLHVGHPEGYTATDI  61

Query  90   VGRFQRMQGRNVLHALAYDAFGLPAEQYAVQTGQHPRITTEQNIATMrgqlrrlglgHDD  149
            ++RF+R QG+NVLH+++ DAFGLPAEQYA++TG++P   T +NIA  + Q+  LG++ D 
Sbjct  62   LSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDW  121

Query  150  RRTFATTDPDYVRWTQWIFTQLFAS--FYDADAP  181
             R   TTDP+Y +WTQWIFT+L+     Y+A+ P
Sbjct  122  DREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVP  155

1598) GPA_10270 in NC_021021


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  502 bits (1895),  Expect = 3e-143, Method: Compositional matrix adjust.
 Identities = 365/897 (41%), Positives = 540/897 (61%), Gaps = 104/897 (11%)

Query  1    MKPYNPHEIEPRWQKAWADADLYKVTEDPSKPKRYVLEMFPYPSG-DIHMGHVRNYTIGD  59
            M  Y+   IEP+WQ  WAD + +K   D+SKPK Y L+MFPYPSG ++H+GH   YT  D
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  60   VIARYSKMRGFDVLHPMGWDAFGLPAENAAIKHHSHPAKWTYENIDTQKASFKRMGFSYD  119
            +++R+ + +G +VLHPMGWDAFGLPAE+ A+   ++PA  T ENI   K  ++ +GFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  120  WDRTVVACDPEYYRWGQWIFLQMWKKGLVERRNSPVNWCPNCETVLANEQV-TEGTCWRC  178
            WDR V + DP+YY+W QWIF ++  KGL    + PVNW  +  T +ANE+V  +GT  R 
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  179  HGAVEKRDLTQWYLKITDYAQEllddldqldGWPERVKQMQANWIGRSEGAEVTFTLCGP  238
              +V ++ + QW LKIT YA E L +  +  +WPE +K+MQ NWIG+S GA+VTF + + 
Sbjct  181  GYPVVRKPMRQWMLKITAYA-ERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDT  239

Query  239  DGEAPAEPTEDDLITVFTTRPDTLFGCSFFLLAPEYKGLMDLVAGTEYEAGVREVVEQAA  298
            D +          +TVFTTRPDTLFG ++ +LAPE  +L+D ++ ++   +V +   QA+
Sbjct  240  DKD----------FTVFTTRPDTLFGATYAVLAPE-HALVDAITTSDQAEAVADYKRQAS  288

Query  299  KVSAVERAQGDREKHGAFTGRYMVNPVNGEKVPVWVADYIVSDYGTGAVMAVPCGDQRDF  358
              S + R++  +EK G  TG Y +NPVNG  +PVW+ADY+++ YGTGA+MAVP  D+RD 
Sbjct  289  LKSDLARTDLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDW  348

Query  359  EFARKYDLPIIPIILGEDDPLFPQLDGVQERRVTSVDWEAAYDAEGVLVQSGKYTGMTGG  418
            EFA++++L IIP++ G +                 V+ EAA+  +G+ ++S+   G+   
Sbjct  349  EFAKQFNLDIIPVLEGGN-----------------VE-EAAFTEDGLHINSDFLDGL---  387

Query  419  KHSPAVDAIIADLEAQGLGRTKVEFRLRDWLISRQRYWGNPIPAVHCPECGLVPVPESDL  478
              ++A+  ++  LEA+G+G  +V +RLRDWL+SRQRYWG+PIP +H  +    +VPES+L
Sbjct  388  DKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESEL  447

Query  479  PVRLPEDIDLAAGETLATHEAFVNT---TCPVCGGPAKRETDTMDTFTCSSWYYLRYTDP  535
            P+ LP   D+ ++ T  +  A V          G  ++RET+TM   + SSWYYLRY DP
Sbjct  448  PLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDP  507

Query  536  HNDELPFAPEKANRWLPVDQYIGGIEHAILHLLYSRFFTKVLRDLGMVDFDEPFANLLCQ  595
            HN E     E  ++WLPVD Y+GG EHA+LHLLY+RF  KVL DLG+V   EPF +L+ Q
Sbjct  508  HNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQ  567

Query  596  GMV-----KDEHG----------------------------ETMSKSKGNVIAPEDMIAE  622
            GM+     +D +G                              MSKS  NV+ P+D++ +
Sbjct  568  GMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQ  627

Query  623  YGADAVRAYILFMAPPDKDLLWDEGGLAGIYKFMNRAWRIVCDLVGQAGDETLYQPGASE  682
            YGAD++R Y +FM+P D  + W E GL G  KF++R  R++                   
Sbjct  628  YGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLIT-------------TKEIT  674

Query  683  AEGVEALKTLVRERHRVAGKVVDDFDRNNFNTAIAAIMELCNAAADYLRKCSPEERAACE  742
             E   AL  +  E  +    V ++ D+ +FNTAIA +M + NAA         E++   +
Sbjct  675  EENSGALDKVYNETVKA---VTEQVDQMKFNTAIAQLMVFVNAANK-------EDKLFSD  724

Query  743  GSRAIDPEVAEVIVKLMAPIAPHWAEELWSAVLGREGSVHTQPWPEFDPEQAKADEVELA  802
             +++        +V+L+AP+APH +EELW A+ +   S+   PWP +D  +   ++VE+ 
Sbjct  725  YAKG--------FVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  803  VQVNGKVKAKITVAADAPEDD--vkaaglaaveaalagkDVKKVVFVPGRLVNIVAK  857
            VQ++GKVKAK+ VA D + ++    A +   V+A +AGKD+ KV+ VP +LVNIV K
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

1599) leuS in NC_021491


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  502 bits (1893),  Expect = 5e-143, Method: Compositional matrix adjust.
 Identities = 361/884 (41%), Positives = 551/884 (63%), Gaps = 74/884 (8%)

Query  5    YTPRDIEAAAQNFWDEQQSFAVTEQPGKDTYYCLSMFPYPSGK-LHMGHVRNYTIGDVIA  63
            Y    IE+  Q FW ++++F    +++K  +Y L MFPYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPMGWDAFGMPAENAAMKNNVAPAKWTYENIDYMKTQLKSLGLAIDWAR  123
            R++R  G NVL+PMGWDAFG+PAE+ AM     PA  T ENI   K Q+++LG++ DW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVTTCKPDYYRWEQWLFTRLFEKGIIYRKNGTVNWDPADQTVLANEQVI-DGRGWRSGAL  182
            EV T  P+YY+W QW+FT+L+EKG+ Y  +  VNW     T +ANE+V+ DG + R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  IEKREIPMYYFRITDYADELLESLDELPGWPEQVKTMQRNWIGKSRGMEVQFPYDQASIG  242
            + ++ +    ++IT YA+ LLE L+E+ +WPE +K MQRNWIGKS G +V F   ++   
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDT---  239

Query  243  HEGTLKVFTTRPDTLMGATYVAVAAEHPLATQAAQGNPALQAFIDECKSGSVAEADMA--  300
             +  + VFTTRPDTL GATY  +A+EH+L    + ++ A    + + K  +   +D+A  
Sbjct  240  -DKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQA--EAVADYKRQASLKSDLART  296

Query  301  --TQEKKGMATSLLVEHPLTGEKLPVWVANYVLMHYGDGAVMAVPAHDERDFEFAHKYKL  358
              ++EK G+ T+    +P+ G  +PVW+A+YVL  YG GA+MAVPAHDERD EFA +++L
Sbjct  297  DLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNL  356

Query  359  PVKAVVRTSAGDEVGNEWQAAYGEHGQLINSGEFDGLDFAGAFDAIEAALIRKELGKSRT  418
             + +V+  +  +E      AA+ E+G  INS+ +DGLD A+A+  +   L    +G+   
Sbjct  357  DIIPVLEGGNVEE------AAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENV  410

Query  419  QFRLRDWGISRQRYWGCPIPIIHCPSCGDVPVPEDQLPVTLP--ENVVPDGAG-SPLARM  475
             +RLRDW +SRQRYWG PIPIIH       +VPE +LP+ LP   ++ P G+G SPLA +
Sbjct  411  TYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANV  470

Query  476  PEFYECSCPKCGTAAKRETDTMDTFVESSWYFARYASPNYDKGLVDPKAANHWLPVDQYI  535
             +  E +    G  ++RET+TM     SSWY+ RY  P+    L D    ++WLPVD Y+
Sbjct  471  TDWLEVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYV  529

Query  536  GGIEHAILHLLYARFFHKLMRDEGLVTSNEPFKNLLTQGMVVAETYYRVASNGGKDWFNP  595
            GG EHA+LHLLYARF HK++ D G+V ++EPF++L+ QGM+++ +Y              
Sbjct  530  GGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY--------------  575

Query  596  ADVEIERDAKAKIIGARL--KTDG--LPVEIG-----GTEKMSKSKNNGVDPQSMIEAYG  646
                  RD+++ ++++    K DG  + VE G     +  KMSKS +N V+P+ ++E YG
Sbjct  576  ------RDSRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYG  629

Query  647  ADTCRLFMMFASPPDMSLEWSDSGVEGASRFLRRVWRLAQA-HVSQGLPGKLDIAALDDA  705
            ADT R++ MF +P D S+ WS+ G+EG+ +FL RV RL  + ++++  +G LD       
Sbjct  630  ADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALD-------  682

Query  706  QKVIRRAIHAAIKQASTDVGQFHKFNTAIAQVMTVMNVLEKAPQASEQDRALLQEGLEAV  765
                 +  + ++K  + +V+Q  KFNTAIAQ+M  +N       A++++  L+ +   + 
Sbjct  683  -----KVYNETVKAVTEQVDQM-KFNTAIAQLMVFVN-------AANKEDKLFSDYAKGF  729

Query  766  TLLLAPITPHISHALWQHLGHAGSVID-AAWPSVDEQAlvqdtvtlvvqvNGKLRGQVEM  824
              L+AP++PH+++ LWQ L  +G  I   +WPS DE  LV++ V +VVQ++GK+++++ +
Sbjct  730  VQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVV  789

Query  825  PaaasreeveaaarsnenvLRFIDGLTIRKVIVVPGKLVNIVAN  868
            +   SREE++  A +NE+V   I G  I KVI VP KLVNIV +
Sbjct  790  AKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

1600) Arch_1000 in NC_014218


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  501 bits (1888),  Expect = 1e-142, Method: Compositional matrix adjust.
 Identities = 350/743 (48%), Positives = 499/743 (68%), Gaps = 59/743 (7%)

Query  219  ARRLAYVDYAPVNWAPGLGTVLANEEVTSEGRSERGNFPVFKRNLRQWMMRITAYSDRLA  278
             + LAY    PVNW   LGT +ANEEV ++G SERG +PV ++ +RQWM++ITAY++RL 
Sbjct  145  EKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLL  204

Query  279  ADLDKVDWPEKVRSMQRNWIGKSQGAHVDFTAHGADSDHTLTVFTTRPDTLFGATFMVVS  338
             DL+ VDWPE ++ MQRNWIGKS GA+V F   ++D D  +TVFTTRPDTLFGAT+ V++
Sbjct  205  EDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKD--FTVFTTRPDTLFGATYAVLA  262

Query  339  PEHPMLAGEALPAEWPENTQPEWTGGAADPATAVKEYQRAASRKSDKERADMEKTKTGVF  398
            PEH+++ + +                ++D A AV +Y+R AS KSD  R+D+ K KTGV 
Sbjct  263  PEHALVDAIT----------------TSDQAEAVADYKRQASLKSDLARTDLAKEKTGVW  306

Query  399  TGIFASNPVNGAQVPVFTADYVMMGYGTGAIMAVPSGDQRDFDFARAYNVPIIPTIQTPE  458
            TG +A NPVNG ++PV  ADYV+ +YGTGAIMAVP+ D+RD +FA+ +N+ IIP ++  +
Sbjct  307  TGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGN  366

Query  459  DFDGESAWTEDGPIINSENSEISLNGLDKVAGKAKITAWLEEKGIGKAAITYRLRDWLFS  518
                E+A TEDG  INS+     L+GLDK ++ AK+  WLE  G+G+  +TYRLRDWLFS
Sbjct  367  --VEEAAFTEDGLHINSD----FLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  519  RQRYWGEPFPIVYDEDGVAHSLPDSMLPVELPDTPDYSPRSFdpddadsepeppLGRLTD  578
            RQRYWGEP+PI+  EDG + ++P+S LP+ LP T D  P +          E+PL+ +TD
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSG--------TGESPLANVTD  472

Query  579  WVNVELDLGDGLKKYTRETNTMPNWAGSCWYELRYIDPRNGEQFIAPENEEYWIGPKEGK  638
            W++V  +  DG+K   RETNTMP+WAGS WY LRYIDP+N E++   E    W+      
Sbjct  473  WLEVTRE--DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWL------  523

Query  639  PAGGTDLYIGGVEHAVLHLLYARFWHKILFDLGYLSSSEPFHKLFNQGYVQAYAYTDSRG  698
                 D+Y+GG EHAVLHLLYARFWHK+L+DLG +++ EPF+KLFNQG + + +Y DSRG
Sbjct  524  ---PVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRG  580

Query  699  QYVPADEVVEVAATDGSGEVTFEWNGQPVNREYGKMGKSLKNIVTPDEMAEQYGADTFRV  758
              V++D V    ++    E      G+ +++  +KM+KSLKN+V PD++ EQYGADT+RV
Sbjct  581  ALVATDKVEKRDGSFFHVE-----TGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRV  635

Query  759  YEMSMGPLDADRPWETRAVVGAQRFLQRLWRNIVDEQTGELVIVDEPTDKETAKLVARTI  818
            YEM MGPLDA  +W   ++ G+++FL+R+ R I   +      + E       K+   T+
Sbjct  636  YEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKE------ITEENSGALDKVYNETV  689

Query  819  RDVREEFDGMRINTAIAKIIV-LNNHVTGKPVTREVAEALVLLASPVAPHIAEELWARL-  876
            + V E+ D M++NTAIA+++V +N       +  + A ++V L +P APH++EELW  L 
Sbjct  690  KAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALT  749

Query  877  GHSESLAHVPFPEVTDESLLVDDTVTCVVQVKGKVRDRLEVPTDISdadlqalalaSEKV  936
            + +ES++ VP P   DES LV++ V  VVQ+KGKV+ +L V+ D+S  +LQ +ALA+EKV
Sbjct  750  ASGESISYVPWPS-YDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKV  808

Query  937  -AQFLDGEPRKVIVRAPNLVNVV  958
             A++ + +  KVI  + +LVN+V
Sbjct  809  QAEIAGKDIIKVIAVPNKLVNIV  831


 Score =  123 bits (450),  Expect = 6e-29, Method: Compositional matrix adjust.
 Identities = 70/147 (48%), Positives = 99/147 (68%), Gaps = 9/147 (6%)

Query  19   IEASWQDRWEREETFNAPNPVGELAGDGELAPEAYFLLDMFPYPSGKGLHVGHPLGFIAT  78
            IE+ WQ  W  ++TF++         + + +   ++ LDMFPYPSG GLHVGHP G+ AT
Sbjct  9    IEPKWQAFWADNHTFKT---------GTDASKPKFYALDMFPYPSGAGLHVGHPEGYTAT  59

Query  79   DCLARYQRMQGKNVLYTMGFDAFGLPAEQYAVQTGQHPRITTEQNIDNMRGQLRRLGMSH  138
            D L+R++R QG NVL  MG DAFGLPAEQYA++TG++P   T +NI N + Q+  LG S 
Sbjct  60   DILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSY  119

Query  139  EKRRSVATTDNDFVGWTQWIFSQIFNS  165
            +  R V TTD ++  WTQWIF+++++ 
Sbjct  120  DWDREVNTTDPNYYKWTQWIFTKLYEK  146

1601) leuS in NC_021192


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  501 bits (1888),  Expect = 1e-142, Method: Compositional matrix adjust.
 Identities = 346/740 (47%), Positives = 497/740 (68%), Gaps = 57/740 (7%)

Query  182  LXYRAXSLXNWCPGLGTVLANEEVTADGRSDRGNFPVFRKRLRQWMMRITAYAdrllddl  241
            L Y A    NW   LGT +ANEEV +DG S+RG +PV RK +RQWM++ITAYA+RLL+DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  242  dvldWPEQVKTMQRNWIGRSTGAVALFSARAASDDGFEVDIEVFTTRPDTLFGATYLVLA  301
            + +DWPE +K MQRNWIG+STGA   F  + +     + D+ VFTTRPDTLFGATY VLA
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDT-----DKDFTVFTTRPDTLFGATYAVLA  262

Query  302  PEHDLVDELVAASWPAGVNPLWTYGGGTPGEaiaayrraiaaKSDLERQE-SREKTXVFL  360
            PEH LVD + ++                 +EA+A Y+R  + KSDL R + ++EKT V  
Sbjct  263  PEHALVDAITTSD---------------QAEAVADYKRQASLKSDLARTDLAKEKTGVWT  307

Query  361  GSYAINPANGEPVPIFIADYVLAGYGTGAIMAVPGHDQRDWDFARAFGLPIVEVIAGGNI  420
            GSYAINP NG  +P+ IADYVLA+YGTGAIMAVP+HD+RDW+FA+ F L I+ V+ GGN+
Sbjct  308  GSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNV  367

Query  421  SESAYTGDGILVNSDYLNGMSVPAAKRAIVDRLESAGRGRARIEFKLRDWLFARQRXWGE  480
             E+A+T DG+ +NSD+L+G+  ++A   +V++LE+ G G   + ++LRDWLF+RQR WGE
Sbjct  368  EEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGE  427

Query  481  PFPIVYDSDGRPHALDEAALPVELPDVPDYSPVLFdpddadsepsppLAKATEWVHVDLD  540
            P+PI+   DG + A+ E+ LP+ LP   D  P         +   +PLA+ T+W++V  +
Sbjct  428  PIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTDWLEVTRE  479

Query  541  LGDGLKPYSRDTNVMPQWAGSSWYELRYTDPHNSERFCAKENEAYWMGPRPAEHGPDDPG  600
              DG+K   R+TN MPQWAGSSWY LRY DPHN+E++   E    W+             
Sbjct  480  --DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWL-------------  523

Query  601  GVDLYVGGAEHAVLHLLYSRFWHKVLYDLGHVSSREPYRRLVNQGYIQAYAYTDARGSYV  660
             VD+YVGGAEHAVLHLLY+RFWHKVLYDLG V+++EP+++L NQG I + +Y D+RG+ V
Sbjct  524  PVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALV  583

Query  661  PAEQVIERGDRFVYPGPDGEVEVFQEFGKIGKSLKNSVSPDEICDAYGADTLRVYEMSMG  720
            ++++V  R++ F     + E+E  Q  +K++KSLKN V+PD++ + YGADTLRVYEM MG
Sbjct  584  ATDKVEKRDGSFFHVETGEELE--QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMG  641

Query  721  PLEASRPWATKDVVGAYRFLQRVWRLVVDEHTGETRVADGVELDIDTLRALHRTIVGVSE  780
            PL+AS +W+  ++ G+ +FL+RV RL+   +  E    ++  LD    +  + T+ +V+E
Sbjct  642  PLDASIAWSEEGLEGSRKFLDRVYRLITTKEITE---ENSGALD----KVYNETVKAVTE  694

Query  781  DFAALRNNTATAKLIEYTNHLTKKHRDAVPRXAVEPLVQMLAPLAPHIAEELWLRLGNTT  840
            +   ++ NTA A+L+ + N   K ++  +       +VQ++AP+APH++EELW  L  + 
Sbjct  695  QVDQMKFNTAIAQLMVFVNAANKEDK--LFSDYAKGFVQLIAPFAPHLGEELWQALTASG  752

Query  841  -SLAHGPFPKADAAYLVDETVEYPVQVNGKVRGRVVVAADTDEETLKAAVLTDEKVQAFL  899
             S++  P P  D + LV++ VE  VQ++GKV++++VVA D   E L+   L++EKVQA +
Sbjct  753  ESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEI  812

Query  900  AGATPRKVIVVAGRLVNLVI  919
            AG    KVI V+ +LVN+VI
Sbjct  813  AGKDIIKVIAVPNKLVNIVI  832


 Score =  125 bits (456),  Expect = 2e-29, Method: Compositional matrix adjust.
 Identities = 66/120 (55%), Positives = 88/120 (74%), Gaps = 0/120 (0%)

Query  13   GAAXXXDKXFVQDMFPYPSGEGLHVGHPLGYIATDVYARYFRMVGRNVLHALGFDAFGLP  72
            G+     K +  DMFPYPSG GLHVGHP GY ATD+ +R+ R  G+NVLH++G DAFGLP
Sbjct  26   GTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSRFKRAQGHNVLHPMGWDAFGLP  85

Query  73   AEQYAVQTGTHPRTRTEANVVNFRRQLGRLGFGHDSRRSFSTTDVDFYRWTQWIFLQIYN  132
            AEQYA++TG +P   T  N+ NF+RQ+  LGF+ D  R  +TTD ++Y+WTQWIF ++Y+
Sbjct  86   AEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1602) Deima_1796 in NC_014958


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  501 bits (1891),  Expect = 6e-143, Method: Compositional matrix adjust.
 Identities = 359/850 (43%), Positives = 522/850 (62%), Gaps = 62/850 (7%)

Query  13   YNPHAIEQKWQTAWDEAGLYAFHEDPRKQKHYALTMFPYPSG-NLHIGHWYAYVVPDARA  71
            Y+  AIE KWQ+ W +   +    D+ K K YAL MFPYPSG  LH+GH  +Y   D  +
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  72   RWMRMRGYNVLFPMGFDAFGLPAENAAIKRGINPRTWTLDNIQYMTGQFRRMGTMIDWSR  131
            R  R +G NVL PMG DAFGLPAE+ A+  G +P   T +NI     Q+  +G   DW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  132  QFATCQPEYYRWNQWFFTRMFERGLAYKKESFVNWDPVDQTVLANEQVV-DGRGERSGAL  190
            +  T +P+YY+W QW+FT+++E+GLAY  E  VNW     T +ANE+V+ DG +ER+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  191  VERRLMSQWHFKITEYAEELL-DFSGTDMPERVRLMQQNWIGKSVGAEVDFATDAGI--V  247
            V R+ M QW +KIT YAE LL D+   D PE ++ MQ+NWIGKS GA+V F         
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  248  TVFTTRPDTLYGATFLVLAPEHPLVDPLTTDEQREAVGAYKEAAGRLSEIDRQAEGREKT  307
            TVFTTRPDTL+GAT+ VLAPEH+LVD++TT +Q EAV+ YK  A+  S++ R   ++EKT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  308  GVFTGAYATHPITGERIPVWIADYVLVTYGSGAIMAVPSGDQRDFEFARKYGLPIVEVVR  367
            GV TG+YA +P+ G  +PVWIADYVL +YG+GAIMAVP+ D+RD EFA+++ L I+ V+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE  363

Query  368  PEGAEALDMDAATEAYTGDGVIVNSGDLNGMRGGKAFIGPVIERLAGYGV-RAKTTYRLR  426
                E         A+T DG+ +NS+ L+G+  + A I+ ++E+L + GV   + TYRLR
Sbjct  364  GGNVEE-------AAFTEDGLHINSDFLDGLDKASA-IAKMVEWLEAEGVGNENVTYRLR  415

Query  427  DWLVSRQRYWGTPIPITYCDTCGAQPVPDDQLPIELPDDVEFLP--TGQSPLKLHPTWSK  484
            DWL SRQRYWG PIPI   +   + +VP+ +LP+ LP   ++ P  TG+SPL     W  
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  485  TTCAKCGGPAERDTDTMDTFVDSSWYMYRFTSPHFDQAPWDKDAAERLTPIDLYTGGIEH  544
             T    G  + R+T+TM    +SSWY  R+  PH  +   D +   +  P+D+Y GG EH
Sbjct  476  VTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEH  534

Query  545  AILHLLYSRFWTKVARDLGLTSNSEPFRALRNQGIILG----------------------  582
            A+LHLLY+RFW KV  DLG+ +  EPF+ L NQG+ILG                      
Sbjct  535  AVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGS  594

Query  583  -----------EDQEKMSKSRGNVIDPDDLVQEYGADTVRTYLMFIAPWEVGGPWSASGI  631
                       +   KMSKS  NV++PDD+V++YGADT+R Y MF++P + + +WS  G+
Sbjct  595  FFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGL  654

Query  632  NGPSKWLSRVWSLYFDENASGPAENTTEAELRYATHTTLQKVTGDFERLSFNTIVAALME  691
            +G+ K L RV  L    + +   EN+   +  Y  + T++ VT + +++ FNT +A LM 
Sbjct  655  EGSRKFLDRVYRLITTKEIT--EENSGALDKVY--NETVKAVTEQVDQMKFNTAIAQLMV  710

Query  692  YTNALVKAKRSPAFGTDAWAEALRIFNLMLAPIVPHIAEELWRE-SGHAQSVHLEAWPSV  750
            + NA  K  +   F     ++  + F  ++AP+ PH++EELW+  ++ ++S+   +WPS 
Sbjct  711  FVNAANKEDK--LF-----SDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSY  763

Query  751  DETATVRDTVTMAVQVNGKVRGQVEISKTatqadamaaaranpdvaKFVDGKDTVKEIFV  810
            DE+  V + V + VQ++GKV++++ ++K  ++ +    A AN  V   + GKD +K I V
Sbjct  764  DESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAV  823

Query  811  PGRIINIVVK  820
            P +++NIV+K
Sbjct  824  PNKLVNIVIK  833

1603) leuS in NC_019905


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  501 bits (1890),  Expect = 8e-143, Method: Compositional matrix adjust.
 Identities = 360/884 (41%), Positives = 551/884 (63%), Gaps = 74/884 (8%)

Query  5    YTPRDIEAAAQKFWDEQQSFAVTEQPGKDTYYCLSMFPYPSGK-LHMGHVRNYTIGDVIA  63
            Y    IE+  Q FW ++++F    +++K  +Y L MFPYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPMGWDAFGMPAENAAMKNNVAPAKWTYENIDYMKTQLKSLGLAIDWAR  123
            R++R  G NVL+PMGWDAFG+PAE+ AM     PA  T ENI   K Q+++LG++ DW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVTTCKPDYYRWEQWLFTRLFEKGIIYRKNGTVNWDPADQTVLANEQVI-DGRGWRSGAL  182
            EV T  P+YY+W QW+FT+L+EKG+ Y  +  VNW     T +ANE+V+ DG + R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  IEKREIPMYYFRITDYADELLESLDELPGWPEQVKTMQRNWIGKSRGMEVQFPYDMASIG  242
            + ++ +    ++IT YA+ LLE L+E+ +WPE +K MQRNWIGKS G +V F       +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTF----KVKD  238

Query  243  HEGTLKVFTTRPDTLMGATYVAVAAEHPLATQAAQGNPALQAFIEECKSGSVAEADMA--  300
             +  + VFTTRPDTL GATY  +A+EH+L    + ++ A    + + K  +   +D+A  
Sbjct  239  TDKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQA--EAVADYKRQASLKSDLART  296

Query  301  --TQEKKGMATSLLVEHPLTGEKLPVWVANYVLMHYGDGAVMAVPAHDERDFEFAHKYNL  358
              ++EK G+ T+    +P+ G  +PVW+A+YVL  YG GA+MAVPAHDERD EFA ++NL
Sbjct  297  DLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNL  356

Query  359  PVKAVVRTSAGDEVGSEWLAAYGEHGQLINSGEFDGLDFAGAFDAIEAALIRKELGKSRT  418
             + +V+  +  +E      AA+ E+G  INS+ +DGLD A+A+  +   L    +G+   
Sbjct  357  DIIPVLEGGNVEE------AAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENV  410

Query  419  QFRLRDWGISRQRYWGCPIPIIHCPSCGDVPVPEDQLPVTLP--ENVVPDGAG-SPLARM  475
             +RLRDW +SRQRYWG PIPIIH       +VPE +LP+ LP   ++ P G+G SPLA +
Sbjct  411  TYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANV  470

Query  476  PEFYECSCPKCGTAAKRETDTMDTFVESSWYFARYASPNYEGGMVDPKAANHWLPVDQYI  535
             +  E +    G  ++RET+TM     SSWY+ RY  P+    + D    ++WLPVD Y+
Sbjct  471  TDWLEVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYV  529

Query  536  GGIEHAILHLLYARFFHKLMRDEGLVTSNEPFKNLLTQGMVVAETYYRVASNGGKDWFNP  595
            GG EHA+LHLLYARF HK++ D G+V ++EPF++L+ QGM+++ +Y              
Sbjct  530  GGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY--------------  575

Query  596  ADVEVERDAKAKIIGARL--KTDG--LPVEIG-----GTEKMSKSKNNGVDPQSMIDQYG  646
                  RD+++ ++++    K DG  + VE G     +  KMSKS +N V+P+ +++QYG
Sbjct  576  ------RDSRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYG  629

Query  647  ADTCRLFMMFASPPDMSLEWSDSGVEGASRFLRRVWRLAQA-HVAQGLPGKLDVAALDDA  705
            ADT R++ MF +P D S+ WS+ G+EG+ +FL RV RL  + ++++  +G LD       
Sbjct  630  ADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALD-------  682

Query  706  QKVIRRAIHTAIKQASTDVGQFHKFNTAIAQVMTVMNVLEKAPQATEQDRALLQEGLEAV  765
                 +  + ++K  + +V+Q  KFNTAIAQ+M  +N       A++++  L+ +   + 
Sbjct  683  -----KVYNETVKAVTEQVDQM-KFNTAIAQLMVFVN-------AANKEDKLFSDYAKGF  729

Query  766  TLLLAPITPHISHELWQQLGHQQAVID-ASWPAVDEaalvqdtvtlvvqvNGKLRGQVEM  824
              L+AP++PH+++ELWQ L      I   +WP+ DE+ LV++ V +VVQ++GK+++++ +
Sbjct  730  VQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVV  789

Query  825  PaaasreeieaaarsnenVLRFIDGLTIRKVIVVPGKLVNIVAN  868
            +   SREE++  A +NE+V   I G  I KVI VP KLVNIV +
Sbjct  790  AKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

1604) Mmol_0582 in NC_012968


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  500 bits (1887),  Expect = 1e-142, Method: Compositional matrix adjust.
 Identities = 347/853 (41%), Positives = 531/853 (63%), Gaps = 69/853 (8%)

Query  5    YPFKDIEQSAQSYWEANQTFAATEQSDKPKYYCLSMFPYPSGR-LHMGHVRNYTIGDVLS  63
            Y    IE   Q++W  N+TF +  ++ KPK+Y L MFPYPSG  LH+GH   YT  D+LS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RFHKMKGFNVMQPMGWDAFGLPAENAAIKNETAPAAWTYSNIEHMKAQLKQLGLGVDWNR  123
            RF + +G NV++PMGWDAFGLPAE+ A+     PA  T  NI + K Q++ LG++ DW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EIATCKPEYYKWEQWLFTELYKKGLIYKKTSTVNWDPVDGTVLANEQVI-DGRGWRSGAL  182
            E+ T  P+YYKW QW+FT LY KGL Y     VNW    GT +ANE+V+ DG + R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VEKRDIPQYFMKITAYAEELLNDLDKLEGWPEQVKTMQRNWIGKSYGCEVEFPIVGQDGN  242
            V ++ + Q  +KITAYAE LL+DL+ ++ WPE +K MQRNWIGKS G +V F + + D +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LKVYTTRPDTLMGatyvavaaehalatlaatDNPALAEFIAECKRGSVAEADIATA----  298
            + V+TTRPDTL GATY  +A+EHAL    +T +   AE +A+ KR +   +D+A +    
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQ--AEAVADYKRQASLKSDLARTDLAK  300

Query  299  EKKGMATGLFVTHPLNGEQLPVWVANYVLASYGEGAVMAVPAHDERDFEFAGKYNLPIKA  358
            EK G+ TG +  +P+NG ++PVW+A+YVLASYG GA+MAVPAHDERD EFA ++NL I +
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VIKHSDVDSLPMTEHGVLFDSAEFNGLDFDGASSAIAADLSAKNLGKRRTQYRLRDWGVS  418
            V+  ++V+  + TE+G+ ++S  ++GLD  +A + +   L A  +G+    YRLRDW  S
Sbjct  361  VLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  419  RQRYWGCPIPIVHCATCGEVPVPAEQLPVVLP--EDVVMDGVG-SPIKKDPSFYETTCPT  475
            RQRYWG PIPI+H       +VP  +LP+VLP   D+   G G SP+ +     E T   
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  476  CHGKATRETDTLDTFFESSWYFARYASFDSNNAMADER-ANYWLPVDQYVGGIEHAILHL  534
               K+ RET+T+     SSWY+ RY   ++ + +ADE   + WLPVD YVGG EHA+LHL
Sbjct  481  G-VKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHL  539

Query  535  LYARFFNKLMRDVGLIKNDEPFTNLLTQGMVL-------------------KEGT-----  570
            LYARF +K++ D+G++   EPF +L+ QGM+L                   ++G+     
Sbjct  540  LYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVE  599

Query  571  ----------KMSKSKGNTVDPQELIDTYGADTARLFMMFAAPPEQSLEWADSGVQGAHR  620
                      KMSKS  N V+P+++++ YGADT R++ MF +P + S+ W++ G++G+++
Sbjct  600  TGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRK  659

Query  621  FLRRLWQATYDHVALGATTAYVSGELNAELKTLRRQLHLTIEKVADDYGRRHSFNTAISS  680
            FL R+    Y  ++    T   SG L+       +  + T+  V+++ ++   FNTAI+ 
Sbjct  660  FLDRV----YRLITTKEITEENSGALD-------KVYNETVKAVTEQVDQMK-FNTAIAQ  707

Query  681  VMELMNSLGKVEGTDDISRQVRQEVLQNVALLLSPIVPHICQALWAELCPNSHILD-AGW  739
            +M ++N+  K +       ++  +  +    L++P+ PH+ + LW  L ++++ +    W
Sbjct  708  LMVFVNAANKED-------KLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPW  760

Query  740  PAADASAMVQDSIEYMIQVNGKLRGSITAAKTETKENLEKLALEQPCVQKFIEENMSVRK  799
            P+ D S +V++ +E ++Q++GK+++ +  AK  ++E+L+ +AL +  VQ  I  +  + K
Sbjct  761  PSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGK-DIIK  819

Query  800  VIVVPNKLINIVV  812
            VI VPNKL+NIV+
Sbjct  820  VIAVPNKLVNIVI  832

1605) leuS in NC_008027


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  500 bits (1885),  Expect = 2e-142, Method: Compositional matrix adjust.
 Identities = 359/885 (41%), Positives = 551/885 (63%), Gaps = 76/885 (8%)

Query  5    YTPRDVEAAAQNAWDEQQSFAVTEQPGKETYYCLSMFPYPSGK-LHMGHVRNYTIGDVIA  63
            Y    +E+  Q  W ++++F    +++K  +Y L MFPYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPMGWDAFGMPAENAAMKNNVAPAKWTYENIDYMKTQLKSLGLAIDWSR  123
            R++R  G NVL+PMGWDAFG+PAE+ AM     PA  T ENI   K Q+++LG++ DW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVTTCKPDYYRWEQWLFTRLFEKGVIYRKNGTVNWDPADQTVLANEQVI-DGRGWRSGAL  182
            EV T  P+YY+W QW+FT+L+EKG+ Y  +  VNW     T +ANE+V+ DG + R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  IEKREIPMYYFRITDYADELLESLDELPGWPEQVKTMQRNWIGKSRGMEVQFPYDQASIG  242
            + ++ +    ++IT YA+ LLE L+E+ +WPE +K MQRNWIGKS G +V F   ++   
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDT---  239

Query  243  HEGTLKVFTTRPDTLMGATYVAVAAEHPLATQAAQGNAALQAFIDECKSGSVAEADMA--  300
             +  + VFTTRPDTL GATY  +A+EH+L    + ++ A    + + K  +   +D+A  
Sbjct  240  -DKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQA--EAVADYKRQASLKSDLART  296

Query  301  --TQEKKGMATSLFVEHPLTGEKLPVWVANYVLMHYGDGAVMAVPAHDERDFEFAHKYNL  358
              ++EK G+ T+ +  +P+ G  +PVW+A+YVL  YG GA+MAVPAHDERD EFA ++NL
Sbjct  297  DLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNL  356

Query  359  PVKAVVRTSAGDDVGSEWLAAYGEHGQLINSGEFDGLDFQGAFDAIEAALIRKDLGKSRT  418
             + +V+  +  ++      AA+ E+G  INS+ +DGLD  +A+  +   L   ++G+   
Sbjct  357  DIIPVLEGGNVEE------AAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENV  410

Query  419  QFRLRDWGISRQRYWGCPIPIIHCPSCGDVPVPEDQLPVTLP--ENVVPDGAG-SPLARM  475
             +RLRDW +SRQRYWG PIPIIH       +VPE +LP+ LP   ++ P G+G SPLA +
Sbjct  411  TYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANV  470

Query  476  PEFYECTCPKCGTAAKRETDTMDTFVESSWYFARYASPNYDKGLVDPKAANHWLPVDQYI  535
             +  E T    G  ++RET+TM     SSWY+ RY  P+    L D    ++WLPVD Y+
Sbjct  471  TDWLEVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYV  529

Query  536  GGIEHAILHLLYARFFHKLMRDEGLVTSNEPFKNLLTQGMVVAETYYRVASNGGKDWFNP  595
            GG EHA+LHLLYARF HK++ D G+V ++EPF++L+ QGM+++ +Y              
Sbjct  530  GGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY--------------  575

Query  596  ADVEIERDAKAKIIGARL--KTDG--LPVEIG-----GTEKMSKSKNNGVDPQSMIEQYG  646
                  RD+++ ++++    K DG  + VE G     +  KMSKS +N V+P+ ++EQYG
Sbjct  576  ------RDSRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYG  629

Query  647  ADTCRLFMMFASPPDMSLEWSDSGVEGASRFLRRVWRLAQA-HVAQGLPGQLDIAALSDE  705
            ADT R++ MF +P D S+ WS+ G+EG+ +FL RV RL  + ++++  +G LD       
Sbjct  630  ADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALD-------  682

Query  706  QKVIRRAIHAAIKQASTDVGQFHKFNTAIAQVMTVMNVLEKAPQVTAQ-DRALLQEGLEA  764
                 +  + ++K  + +V+Q  KFNTAIAQ+M  +N  +K  ++ ++  ++++Q     
Sbjct  683  -----KVYNETVKAVTEQVDQM-KFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQ-----  731

Query  765  VTLLLAPITPHISHELWKQLGHEQAVID-ATWPSVDESAlvqdtvtlvvqvNGKLRGQVE  823
               L+AP++PH+++ELW+ L      I    WPS DES LV++ V +VVQ++GK+++++ 
Sbjct  732  ---LIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLV  788

Query  824  MPaaasreeieaaarnnenVLRFTDGLTIRKVIVVPGKLVNIVAN  868
            ++   SREE++  A  NE+V     G  I KVI VP KLVNIV +
Sbjct  789  VAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

1606) PPS_4636 in NC_015733


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  500 bits (1886),  Expect = 2e-142, Method: Compositional matrix adjust.
 Identities = 360/884 (41%), Positives = 549/884 (63%), Gaps = 74/884 (8%)

Query  5    YTPRDIEAAAQKFWDEQQSFAVTEQPGKDTYYCLSMFPYPSGK-LHMGHVRNYTIGDVIA  63
            Y    IE+  Q FW ++++F    +++K  +Y L MFPYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPMGWDAFGMPAENAAMKNNVAPAKWTYENIDYMKTQLKSLGLAIDWAR  123
            R++R  G NVL+PMGWDAFG+PAE+ AM     PA  T ENI   K Q+++LG++ DW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVTTCKPDYYRWEQWLFTRLFEKGIIYRKNGTVNWDPADQTVLANEQVI-DGRGWRSGAL  182
            EV T  P+YY+W QW+FT+L+EKG+ Y  +  VNW     T +ANE+V+ DG + R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  IEKREIPMYYFRITDYADELLESLDELPGWPEQVKTMQRNWIGKSRGMEVQFPYDLASIG  242
            + ++ +    ++IT YA+ LLE L+E+ +WPE +K MQRNWIGKS G +V F       +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTF----KVKD  238

Query  243  HEGTLKVFTTRPDTLMGATYVAVAAEHPLATQAAQGNPALQAFIDECKSGSVAEADMA--  300
             +  + VFTTRPDTL GATY  +A+EH+L    + ++ A    + + K  +   +D+A  
Sbjct  239  TDKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQA--EAVADYKRQASLKSDLART  296

Query  301  --TQEKKGMATSLLVEHPLTGEKLPVWVANYVLMHYGDGAVMAVPAHDERDFEFAHKYNL  358
              ++EK G+ T+    +P+ G  +PVW+A+YVL  YG GA+MAVPAHDERD EFA ++NL
Sbjct  297  DLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNL  356

Query  359  PVKAVVRTSAGDEVGNEWLAAYGEHGQLINSGEFDGLDFAGAFDAIEAALIRKELGKSRT  418
             + +V+  +  +E      AA+ E+G  INS+ +DGLD A+A+  +   L    +G+   
Sbjct  357  DIIPVLEGGNVEE------AAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENV  410

Query  419  QFRLRDWGISRQRYWGCPIPIIHCPSCGDVPVPEDQLPVTLP--ENVVPDGAG-SPLARM  475
             +RLRDW +SRQRYWG PIPIIH       +VPE +LP+ LP   ++ P G+G SPLA +
Sbjct  411  TYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANV  470

Query  476  PEFYECNCPKCGTAAKRETDTMDTFVESSWYFARYASPNYEGGMVDPKAANHWLPVDQYI  535
             +  E      G  ++RET+TM     SSWY+ RY  P+    + D    ++WLPVD Y+
Sbjct  471  TDWLEVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYV  529

Query  536  GGIEHAILHLLYARFFHKLMRDEGLVTSNEPFKNLLTQGMVVAETYYRVASNGGKDWFNP  595
            GG EHA+LHLLYARF HK++ D G+V ++EPF++L+ QGM+++ +Y              
Sbjct  530  GGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY--------------  575

Query  596  ADVEVERDAKAKIIGARL--KTDG--LPVEIG-----GTEKMSKSKNNGVDPQSMIDQYG  646
                  RD+++ ++++    K DG  + VE G     +  KMSKS +N V+P+ +++QYG
Sbjct  576  ------RDSRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYG  629

Query  647  ADTCRLFMMFASPPDMSLEWSDSGVEGASRFLRRVWRLAQA-HVAQGLPGKLDVAALDDA  705
            ADT R++ MF +P D S+ WS+ G+EG+ +FL RV RL  + ++++  +G LD       
Sbjct  630  ADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALD-------  682

Query  706  QKVIRRAIHAAIKQASTDVGQFHKFNTAIAQVMTVMNVLEKAPQATEQDRALLQEGLEAV  765
                 +  + ++K  + +V+Q  KFNTAIAQ+M  +N       A++++  L+ +   + 
Sbjct  683  -----KVYNETVKAVTEQVDQM-KFNTAIAQLMVFVN-------AANKEDKLFSDYAKGF  729

Query  766  TLLLAPITPHISHELWQQLGHQQAVID-ANWPTVDEaalvqdtvtlvvqvNGKLRGQVEM  824
              L+AP++PH+++ELWQ L      I    WP+ DE+ LV++ V +VVQ++GK+++++ +
Sbjct  730  VQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVV  789

Query  825  PaaasreeieaaarsnenVLRFIDGLTIRKVIVVPGKLVNIVAN  868
            +   SREE++  A +NE+V   I G  I KVI VP KLVNIV +
Sbjct  790  AKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

1607) Mfla_2155 in NC_007947


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  499 bits (1882),  Expect = 3e-142, Method: Compositional matrix adjust.
 Identities = 343/857 (41%), Positives = 520/857 (61%), Gaps = 73/857 (8%)

Query  5    YPFRDIEQQAQQYWESNATFTATEVSDKPKYYCLSMFPYPSGK-LHMGHVRNYTIGDVLS  63
            Y    IE + Q +W  N TF +   + KPK+Y L MFPYPSG  LH+GH   YT  D+LS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RFHRMRGYNVMQPMGWDAFGLPAENAAIKHNVAPAGWTYSNIEHMKGQLKSLGLAVDWQR  123
            RF R +G NV++PMGWDAFGLPAE+ A+     PA  T  NI + K Q+++LG++ DW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EIATCKPDYYRWEQWLFTELYKKGLIYKKTATVNWDPVDQTVLANEQVI-DGRGWRSGAL  182
            E+ T  P+YY+W QW+FT LY KGL Y     VNW     T +ANE+V+ DG + R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VEKRDIPQYFMKITAYaeelladldkldGWPEQVKTMQRNWIGKSYGCEVEFPLAVGNGT  242
            V ++ + Q  +KITAY  E L +     +WPE +K MQRNWIGKS G +V F +   +  
Sbjct  184  VVRKPMRQWMLKITAY-AERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LKVYTTRPDTLMGATYVAIAAEHALATQAAKDNPALQAFIEECKRGSVAEADLATA----  298
            + V+TTRPDTL GATY  +A+EHAL    +  + A    + + KR +   +DLA +    
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQA--EAVADYKRQASLKSDLARTDLAK  300

Query  299  EKKGMNSGLFVLHPITGEKLPVWVANYVLISYGEGAVMAVPAHDERDFEFASKYKLPIKA  358
            EK G+ +G + ++P+ G  +PVW+A+YVL SYG GA+MAVPAHDERD EFA +++L I +
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VIKPAHGELELPLQAAYTEHGILFDSGDFNGLDFSQasdaiaaalaaKNLGKRRTQYRLR  418
            V+  ++ E     +AA+TE+G+ ++S+ ++GLD + A   +   L A  +G+    YRLR
Sbjct  361  VLEGGNVE-----EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  419  DWGISRQRYWGCPIPIVHCPSCGEVPVPAEQLPVVLP--EDVVMDGVG-SPIKKDPAFYE  475
            DW +SRQRYWG PIPI+H       +VP  +LP+VLP   D+   G G SP+ +     E
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  476  TTCPSCGEKATRETDTMDTFVESSWYFARYASFDAHSSMVDER-ANYWLPVDQYIGGIEH  534
             T    G K+ RET+TM     SSWY+ RY   +    + DE   + WLPVD Y+GG EH
Sbjct  476  VTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEH  534

Query  535  AILHLLYARFFNKLMRDVGLVRHDEPFTKLLTQGMVL-------------------KDGS  575
            A+LHLLYARF +K++ D+G+V   EPF KL+ QGM+L                   +DGS
Sbjct  535  AVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGS  594

Query  576  ---------------KMSKSKGNTVDPQELIDNYGADTARLFMMFAAPPEQSLEWSDAGV  620
                           KMSKS  N V+P++++++YGADT R++ MF +P + S+ WS+ G+
Sbjct  595  FFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGL  654

Query  621  EGAHRFLKRVWTAVANHVESGIVAAFTMGDLSAELKAFRRQLHQTIEKVTDDYGRRHAFN  680
            EG+++FL RV   ++       ++    G L    K +    ++T+  VT++ ++   FN
Sbjct  655  EGSRKFLDRVYRLITTKE----ITEENSGALD---KVY----NETVKAVTEQVDQMK-FN  702

Query  681  TAIAAVMELMNAYAKIEGHDATTRAIRQEALENIILLLSPIVPHICHALWQALRPGTQLL  740
            TAIA +M ++NA  K +        +  +    ++ L++P+ PH+ + LWQAL ++ + +
Sbjct  703  TAIAQLMVFVNAANKED-------KLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESI  755

Query  741  D-TRWPVANKAAMVQDEIELVLQVNGKLRGSMTVSRTLDKAAIEALAVQQECIQKYLAEG  799
                WP  + + +V++++E+V+Q++GK+++ + V++ L +  ++ +A+ +E +Q  +A  
Sbjct  756  SYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGK  815

Query  800  SVRKIIVVPNKLVNIVV  816
             + K+I VPNKLVNIV+
Sbjct  816  DIIKVIAVPNKLVNIVI  832

1608) leuS in NC_010501


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  499 bits (1882),  Expect = 3e-142, Method: Compositional matrix adjust.
 Identities = 361/884 (41%), Positives = 548/884 (62%), Gaps = 74/884 (8%)

Query  5    YTPRDIEAAAQHFWDEQQSFAVTEQPGKDTYYCLSMFPYPSGK-LHMGHVRNYTIGDVIA  63
            Y    IE+  Q FW ++++F    +++K  +Y L MFPYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPMGWDAFGMPAENAAMKNNVAPAKWTYENIDYMKTQLKSLGLAIDWAR  123
            R++R  G NVL+PMGWDAFG+PAE+ AM     PA  T ENI   K Q+++LG++ DW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVTTCKPDYYRWEQWLFTRLFEKGIIYRKNGTVNWDPADQTVLANEQVI-DGRGWRSGAL  182
            EV T  P+YY+W QW+FT+L+EKG+ Y  +  VNW     T +ANE+V+ DG + R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  IEKREIPMYYFRITDYADELLESLDELPGWPEQVKTMQRNWIGKSRGMEVQFPYDQASIG  242
            + ++ +    ++IT YA+ LLE L+E+ +WPE +K MQRNWIGKS G +V F   ++   
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDT---  239

Query  243  HEGTLKVFTTRPDTLMGATYVAVAAEHPLATQAAQGNPALQAFIDECKSGSVAEADMA--  300
             +  + VFTTRPDTL GATY  +A+EH+L    + ++ A    + + K  +   +D+A  
Sbjct  240  -DKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQA--EAVADYKRQASLKSDLART  296

Query  301  --TQEKKGMPTSLLVEHPLTGEKLPVWVANYVLMHYGDGAVMAVPAHDERDFEFAHKYNL  358
              ++EK G+ T+    +P+ G  +PVW+A+YVL  YG GA+MAVPAHDERD EFA ++NL
Sbjct  297  DLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNL  356

Query  359  PVKAVVRTSAGDEVGSEWQAAYGEHGQLINSGEFDGLDFAGAFDAIEAALIRKELGKSRT  418
             + +V+  +  +E      AA+ E+G  INS+ +DGLD A+A+  +   L    +G+   
Sbjct  357  DIIPVLEGGNVEE------AAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENV  410

Query  419  QFRLRDWGISRQRYWGCPIPIIHCPSCGDVPVPEDQLPVTLP--ENVVPDGAG-SPLARM  475
             +RLRDW +SRQRYWG PIPIIH       +VPE +LP+ LP   ++ P G+G SPLA +
Sbjct  411  TYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANV  470

Query  476  PEFYECSCPKCGAAAKRETDTMDTFVESSWYFARYASPNYDKGLVDPKAANHWLPVDQYI  535
             +  E +    G  ++RET+TM     SSWY+ RY  P+    L D    ++WLPVD Y+
Sbjct  471  TDWLEVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYV  529

Query  536  GGIEHAILHLLYARFFHKLMRDEGLVTSNEPFKNLLTQGMVVAETYYRVASNGGKDWFNP  595
            GG EHA+LHLLYARF HK++ D G+V ++EPF++L+ QGM+++ +Y              
Sbjct  530  GGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY--------------  575

Query  596  ADVEIERDAKAKIIGARL--KTDG--LPVEIG-----GTEKMSKSKNNGVDPQSMIEAYG  646
                  RD+++ ++++    K DG  + VE G     +  KMSKS +N V+P+ ++E YG
Sbjct  576  ------RDSRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYG  629

Query  647  ADTCRLFMMFASPPDMSLEWSDSGVEGASRFLRRVWRL-AQGHVNQGLPGKLDLAALNDE  705
            ADT R++ MF +P D S+ WS+ G+EG+ +FL RV RL +  ++ +  +G LD       
Sbjct  630  ADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALD-------  682

Query  706  QKVIRRAIHTAIKQASTDVGQYHKFNTAIAQVMTVMNVLEKAPQSTEQDRALLQEGLEAV  765
                 +  + ++K  + +V+Q  KFNTAIAQ+M  +N       +++++  L+ +   + 
Sbjct  683  -----KVYNETVKAVTEQVDQ-MKFNTAIAQLMVFVN-------AANKEDKLFSDYAKGF  729

Query  766  TLLLAPITPHISHELWKALGHEQAVID-ACWPVVDESAlvqdtvtlvvqvNGKLRGQVEM  824
              L+AP++PH+++ELW+AL      I    WP  DES LV++ V +VVQ++GK+++++ +
Sbjct  730  VQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVV  789

Query  825  PaaasreeieaaarnnenVLRFIDGLTIRKVIVVPGKLVNIVAN  868
            +   SREE++  A  NE+V   I G  I KVI VP KLVNIV +
Sbjct  790  AKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

1609) leuS in NC_013169


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  499 bits (1882),  Expect = 4e-142, Method: Compositional matrix adjust.
 Identities = 341/760 (45%), Positives = 492/760 (65%), Gaps = 76/760 (10%)

Query  228  RRLAYLSDAPVNWVPGLGTVVANEEVTADGRSERGNFPVFKRNLPQWMMRITAYADRLVD  287
            + LAY ++ PVNWV  LGT +ANEEV +DG SERG +PV ++ + QWM++ITAYA+RL++
Sbjct  146  KGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLE  205

Query  288  DLDRLQWPESVASMQRNWIGRSTGAAVFFEVAVPNAASLPADADGRTRLEVFTTRPDTLF  347
            DL+ ++WPES+  MQRNWIG+STGA V F V            D    + VFTTRPDTLF
Sbjct  206  DLEEVDWPESIKDMQRNWIGKSTGANVTFKV-----------KDTDKDFTVFTTRPDTLF  254

Query  348  GATFMVVAPEHPVADAVPAQWPEGTGEAWTGGHATPaeavaayrqaaaRKSDLDRQADDR  407
            GAT+ V+APEH++ DA+            T+++A +             KSDL R    +
Sbjct  255  GATYAVLAPEHALVDAIT-----------TSDQAEAVADYKRQASL---KSDLARTDLAK  300

Query  408  AKTGVFTGIWATNPVTEERVPVFMADYVLMGYGTGAIMAVPAQDQRDWDFATTYELPIVR  467
             KTGV TG  A NPV    +PV +ADYVL +YGTGAIMAVPA+D+RDW+FA  ++L I+ 
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  468  TVQPSEGHDEDTAFTGEGPAINSANEQVDLNGLGVAEAKDRIIAHLESTGSGHRTITYKL  527
             ++   G+ E++AFT +G  INS      L+GL+ A A  +++  LE+ G G+  +TY+L
Sbjct  361  VLE--GGNVEEAAFTEDGLHINSDF----LDGLDKASAIAKMVEWLEAEGVGNENVTYRL  414

Query  528  RDWLFSRQRYWGEPFPIV-WDADGRAHAVPADQLPVELPEVADYSPKTYDPEDWDTQPES  586
            RDWLFSRQRYWGEP+PI+ W+ DG + AVP  +LP+ LP   D  P            ES
Sbjct  415  RDWLFSRQRYWGEPIPIIHWE-DGTSTAVPESELPLVLPVTKDIRP--------SGTGES  465

Query  587  PLGRNADWVNVTLDLGDGPQQYRRETNTMPNWAGSCWYELRYTDPTNDQAFVDPAVEEYW  646
            PL+  +DW++VT +  DG +  RRETNTMP+WAGS WY LRY DP N + + D  +   W
Sbjct  466  PLANVTDWLEVTRE--DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQW  522

Query  647  MGPGRGFGEGVADDPGGVDLYVGGVEHAVLHLLYARFWHKVLFDLGHLSSDEPFRRLFNQ  706
            +                VD+YVGG EHAVLHLLYARFWHKVL+DLG +++ EPF++LFNQ
Sbjct  523  L---------------PVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQ  567

Query  707  GMVQAFAFRDDRGQPVPAAEVTETQAPDHPRAQNGILYEWE-GQPVTREYGKMGKSLKNV  765
            GM+ + ++RD RG  V++  V           ++G +++ E G+ + +  +KM+KSLKNV
Sbjct  568  GMILGTSYRDSRGALVATDKVEK---------RDGSFFHVETGEELEQAPAKMSKSLKNV  618

Query  766  VTPDEMCAQYGADVFRVYEMSMGPLDASRPWETRAVVGSQRFLQRLWRAIVDETTGELLV  825
            V PD++  QYGAD +RVYEM MGPLDAS +W   ++ GS++FL+R+ R I   TT E+  
Sbjct  619  VNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLI---TTKEITE  675

Query  826  TDDAAQDETLRALHRTIAGVADDFENLRFNTAVSKLIELTNTVTKLPAVPREVAEPLVQM  885
             + +A D   +  + T+ +V+++ ++++FNTA+++L+ + N+  K   +  + A  +VQ+
Sbjct  676  ENSGALD---KVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQL  732

Query  886  VAPLAPHVAEELWSRL-GHESSLATEPFPQADEAMLVAETVTCVVQIKGKVRDRLEVSPE  944
            +AP+APH++EELW  L +   S++  P P  DE+ LV + V  VVQIKGKV+ +L V+ +
Sbjct  733  IAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKD  792

Query  945  IPADDLEAQALASERVQQFIDGAPVRKVIVKAPTLVNIVV  984
            ++ ++L+  ALA+E+VQ  I G  + KVI  +  LVNIV+
Sbjct  793  LSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832


 Score =  130 bits (475),  Expect = 6e-31, Method: Compositional matrix adjust.
 Identities = 74/155 (48%), Positives = 102/155 (66%), Gaps = 15/155 (9%)

Query  19   NEIEARWQDRWAAEGTFRAPNPTGDLAPADPSEREAVAARPKVMIQDMFPYPSGAGLHVG  78
              IE++WQ  WA + TF++                  A++PK    DMFPYPSGAGLHVG
Sbjct  7    TAIEPKWQAFWADNHTFKTGTD---------------ASKPKFYALDMFPYPSGAGLHVG  51

Query  79   HPLGFIATDVYARYQRTTGRNVLYTMGFDAFGLPAEQYAVATGQHPRTTTEANMETYRRQ  138
            HP G+ ATD+ +R++R+ G+NVL  MG DAFGLPAEQYA+ TG++P   T  N+  ++RQ
Sbjct  52   HPEGYTATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQ  111

Query  139  LRQLGLSHDDQRTFATIDPDYYRWTQWIFLQVYNS  173
            +  LG+S D +R   T DP+YY+WTQWIF ++Y+ 
Sbjct  112  INALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEK  146

1610) leuS in NC_007492


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  499 bits (1881),  Expect = 4e-142, Method: Compositional matrix adjust.
 Identities = 364/875 (42%), Positives = 552/875 (64%), Gaps = 60/875 (6%)

Query  5    YQPREIEAAAQSFWDEQKSFEVSEQPGKETYYCLSMFPYPSGK-LHMGHVRNYTIGDVIS  63
            Y+   IE+  Q+FW ++ +F  + +++K  +Y L MFPYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPMGWDAFGMPAENAAMKNNVAPAKWTYENIAYMKSQLRSLGLAVDWSR  123
            R++R  G NVL+PMGWDAFG+PAE+ AM     PA  T ENIA  K Q+ +LG++ DW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVTTCKPDYYRWEQWLFTRLFEKGVIYRKNGTVNWDPIDQTVLANEQVI-DGRGWRSGAL  182
            EV T  P+YY+W QW+FT+L+EKG+ Y  +  VNW     T +ANE+V+ DG + R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  IEKREIPMYYFKITAYADELLESLDELTGWPEQVKTMQRNWIGKSRGMEVQFPYNVDSIG  242
            + ++ +    +KITAYA+ LLE L+E+ +WPE +K MQRNWIGKS G +V F  +V   +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTF--KVKDTD  240

Query  243  ESGTLKVFTTRPDTLMGATYvavaaehhlaalaaKNNPELQAFIAECKGGSVAEADVA--  300
                + VFTTRPDTL GATY  +A+EH L    + ++      +A+ K  +   +D+A  
Sbjct  241  KD--FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQA--EAVADYKRQASLKSDLART  296

Query  301  --TQEKKGLPTGLFVEHPLTGEKLPVWVANYVLMHYGDGAVMAVPAHDERDFEFAHKYNL  358
              ++EK G+ TG +  +P+ G  +PVW+A+YVL  YG GA+MAVPAHDERD EFA ++NL
Sbjct  297  DLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNL  356

Query  359  PVKSVVRTSSGDTNPAPWQDAYGEHGTLINSGEFDGLDFAGAFDAMEVALIKKNLGASRT  418
             + +V+  ++ +      + A+ E+G  INS+ +DGLD A+A+  M   L    +G    
Sbjct  357  DIIPVLEGGNVE------EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENV  410

Query  419  QFRLRDWGISRQRYWGCPIPIIHCDACGDVPVPEDQlpvvlpedvvpdGAG---SPLARM  475
             +RLRDW +SRQRYWG PIPIIH +     +VPE +LP+VLP       +G   SPLA +
Sbjct  411  TYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANV  470

Query  476  PEFYECTCPKCGQPAKRETDTMDTFVESSWYYARYASPHFEGGLVEKSAADHWLPVDQYI  535
             +  E T    G  ++RET+TM     SSWYY RY  PH    L +     +WLPVD Y+
Sbjct  471  TDWLEVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYV  529

Query  536  GGIEHAILHLLYARFFHKLMRDEGLVSSNEPFKNLLTQGMVVAETYYRREANGAYTWFNP  595
            GG EHA+LHLLYARF HK++ D G+V+++EPF++L+ QGM+++ +Y  R++ GA      
Sbjct  530  GGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY--RDSRGA------  581

Query  596  ADVELERDSKAKVISAKLIADGLPVEIG-GTEKMAKSKNNGVDPQSMIDQFGADTCRLFM  654
                L    K     + ++      E+  +  KM+KS +N V+P+ +++Q+GADT R++ 
Sbjct  582  ----LVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYE  637

Query  655  MFASPPDMSAEWSDSGVEGSHRFLKRVWRLAQA-HITQGLPGKLDIASLNDEQKVIRRAI  713
            MF +P D S  WS+ G+EGS++FL RV RL  + +IT+  +G LD            +  
Sbjct  638  MFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALD------------KVY  685

Query  714  HQAIKQASHDVGQNHKFNTAIAQVMTLMNVLEKAAQA-TEQDRALVQEGLETVTLLLAPI  772
            ++++K  +++V+Q  KFNTAIAQ+M ++N  +K  +  ++  +++VQ        L+AP+
Sbjct  686  NETVKAVTEQVDQM-KFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQ--------LIAPF  736

Query  773  TPHISHELWNRLGHADPVID-ASWPVLDESALVQDSLTLVIQVNGKLRGQIEMPaaatre  831
            +PH+++ELW+ L  ++  I   +WP  DES LV++ + +V+Q++GK+++++ ++   +RE
Sbjct  737  APHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSRE  796

Query  832  eveaaaranenvLRFVDGLTIRKVIVVPGKLVNIV  866
            E++  A ANE+V   + G  I KVI VP KLVNIV
Sbjct  797  ELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIV  831

1611) leuS in NC_020891


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  499 bits (1881),  Expect = 4e-142, Method: Compositional matrix adjust.
 Identities = 355/873 (41%), Positives = 517/873 (60%), Gaps = 83/873 (9%)

Query  13   YDFRAIEAEWSAVWEREQPFRTPDASDSRPRKYILDMFPYPSG-DLHMGHAEAFALGDAV  71
            YD  AIE+ W A W  ++ F+T ++  S+P+ Y LDMFPYPSG +LH+GH+E+++  D +
Sbjct  4    YDHTAIEPKWQAFWADNHTFKT-GTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDIL  62

Query  72   ARYWRQQGFNVLHPIGWDSFGLPAENAAIKRGVDPREWTYANIETQKQSMKRYGLSFDWE  131
            +R+ R QG NVLHP+GWD+FGLPAE+ A+  G DP E T  NI   K+ ++  G+S+DW+
Sbjct  63   SRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWD  122

Query  132  RELHTSDPEYYRWNQWLFLKMHEKGLAYRKDSWVNWDPVDQTVLANEQVLPDGTSDRSGA  191
            RE++T+DP+YY+W QW+F K+ EKGLAY  +  VNW     T +ANE+VLPDGTS+R+G 
Sbjct  123  REVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGY  182

Query  192  VVVKKKLTQWYLRITDYADRLVDDLNQLEGTWPAKVLSMQRNWIGRSIGAEVDFVVDGRD  251
             VV+K + QW L+IT YA+RL++DL++++  WP  +  MQRNWIG+S GA+V F V + D
Sbjct  183  PVVRKPMRQWMLKITAYAERLLEDLEEVD--WPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  252  EPVTVFTTRPDTLHGATFMVVAPDSDLAAELVEGASEEIREDFRGYLERTQRLN-EIERS  310
               TVFTTRPDTL GAT+ V+AP+  L   +  +   E   D++    R   L+ ++ R+
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYK----RQASLKSDLART  296

Query  311  TTDRPKTGIPLGRTAINPVNGERIPVWAADYVLADYGTGAVMAVPAHDQRDLDFARAFDL  370
               + KTG+  G  AINPVNG  +PVW ADYVLA YGTGA+MAVPAHD+RD +FA+ F+L
Sbjct  297  DLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNL  356

Query  371  PVRVVVDTTQPVTGAIRIIPEDGELPDLEEVLPGRTGVALPGEGRLINSGSLNGLSKQPA  430
             +  V+              E+G++ +           A+  +G  INS+ L+GL K +A
Sbjct  357  DIIPVL--------------EGGNVEE----------AAFTEDGLHINSDFLDGLDKASA  392

Query  431  IKRVIEQLEAEGRGRAAKSYRLRDWLISRQRFWGTPIPIVYDAEGREIRVPEDQLPVRLP  490
            I +++E LEAEG G    +YRLRDWL+SRQR+WG PIPI+   +G    VPE +LP+ LP
Sbjct  393  IAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLP  452

Query  491  DTAGLDLTPKGKSPLAAATEWSNVPSPVDGSPATRDPDTMDTFMDSSWYWLRFLSPNDAT  550
             T ++  +  G SPLA  T+W +V    DG  + R+ +TM    +SSWY LR++ P+++ 
Sbjct  453  VTKDIRPSGTGESPLANVTDWLEVTRE-DGVKGRRETNTMPQWAGSSWYYLRYIDPHNTE  511

Query  551  KAFDPADADRWAPIDQYVGGVEHAILHLLYSRFITKVLFDLGYVTFTEPFSALLNQGMVL  610
            K  D     +W P+D YVGG EHA+LHLLY+RF  KVL+DLG V   EPF  L+NQGM+L
Sbjct  512  KLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMIL  571

Query  611  sggskmskskg--------------gVDLGSEID---------------------RHGVD  635
            + + + S++                 V+ G E++                     + G D
Sbjct  572  GTSYRDSRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGAD  631

Query  636  AIRLTMAFAGPPEDDIDWEDVSPSGSAKFLARAWRLTGDITSAPEVEWKTGDEALRRVTH  695
            ++R+   F GP +  I W + +  GS KFL R  RL      + E        AL +V +
Sbjct  632  TLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITEE-----NSGALDKVYN  686

Query  696  RFLAEAPGMLEAFKFNVVIARTMELVNAIRKTIDQGPGGGDAAVREATEVVAIALSLFAP  755
              +      ++  KFN  IA+ M +VNA  K         D    + +      ++ FAP
Sbjct  687  ETVKAVTEQVDQMKFNTAIAQLMVFVNAANK--------EDKLFSDYAKGFVQLIAPFAP  738

Query  756  YTAEDMWKRLGREG-SVAFAGWRKAERnllvvntvtavvqvDGKVRDKLEVDAKIGADEL  814
              +E++W+ L   G S+++  W   + + LV N V  VVQ+ GKV+ KL V   ++ +EL
Sbjct  739  HLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREEL  798

Query  815  EALARETAGVKRSTAGRTIDKVIVRAPKIVSIT  847
            + +A     V+   AG+ I KVI  + K+V+I 
Sbjct  799  QEVALANEKVQAEIAGKDIIKVIAVPNKLVNIV  831

1612) leuS in NC_009439


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  499 bits (1881),  Expect = 5e-142, Method: Compositional matrix adjust.
 Identities = 366/887 (42%), Positives = 552/887 (63%), Gaps = 78/887 (8%)

Query  41   YSPREIEAAAQSHWDAQKSFVVSEQPGKDTFYCLSMFPYPSGK-LHMGHVRNYTIGDVIA  99
            Y    IE+  Q+ W  + +F  + +++K  FY L MFPYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  100  RYQRMQGKNVLQPMGWDAFGMPAENAAMKNQVAPAKWTYENIAYMKSQLKSLGLAIDWTR  159
            R++R QG NVL+PMGWDAFG+PAE+ AM     PA  T ENIA  K Q+++LG++ DW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  160  EVTTCKPDYYRWEQWLFTRLFEKGVIYRKNGTVNWDPVDQTVLANEQVI-DGRGWRSGAL  218
            EV T  P+YY+W QW+FT+L+EKG+ Y  +  VNW     T +ANE+V+ DG + R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  219  IEKREIPMYYFKITAYAdellssldeldGWPEQVKTMQRNWIGKSFGADIVFDYDVASIG  278
            + ++ +    +KITAYA E L    E  +WPE +K MQRNWIGKS GA++ F       +
Sbjct  184  VVRKPMRQWMLKITAYA-ERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFK----VKD  238

Query  279  IDGQLKVYSTRPDTLMGATYVAVAAEHPLAQRAAESNPAIAAFIAECKAGSVAEADMA--  336
             D ++ V++TRPDTL GATY  +A+EH+L +  + S+ A A  +A+ K  +   +D+A  
Sbjct  239  TDKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEA--VADYKRQASLKSDLART  296

Query  337  --TMEKKGLATGQFVIHPLTGDKLPVFVANYVLWGYGEGAVMAVPAHDERDFEFANKYDL  394
              + EK G+ TG + I+P+ G  +PV +A+YVL +YG GA+MAVPAHDERD EFA++++L
Sbjct  297  DLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNL  356

Query  395  PIKQVYTGEGKDYDASTWQDWYGDKAGLTTINSGKYDGLDFSAAFDAIVGDLEASAHGAR  454
             I  V  G   +  A T         GL  INS+  DGLD ++A+  +V  LEA + G  
Sbjct  357  DIIPVLEGGNVEEAAFT-------EDGL-HINSDFLDGLDKASAIAKMVEWLEAEGVGNE  408

Query  455  KTQFRLRDWGISRQRYWGCPIPIIHCDSCGDVPVPEDQlpvvlpedvvpdGAG---SPLA  511
            +  +RLRDW +SRQRYWG PIPIIH +     +VPE +LP+VLP       +G   SPLA
Sbjct  409  NVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLA  468

Query  512  KMPEFYECTCPKCGAPAKRETDTMDTFVESSWYFARYASPNYEGGMVDPQAANHWLPVDQ  571
            ++ +  E T    G  ++RET+TM     SSWY+ RY  P+    + D +  ++WLPVD 
Sbjct  469  NVTDWLEVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDI  527

Query  572  YIGGIEHAILHLLYARFFHKLMRDEGLVSSNEPFKNLLTQGMVVAETYYRTLENGGKDWF  631
            Y+GG EHA+LHLLYARF HK++ D G+V+++EPF++L+ QGM+++ +Y            
Sbjct  528  YVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY------------  575

Query  632  NPADVEVERDAKAKVIGAKL--KSDG--LPVEIG-----GTEKMSKSKNNGVDPQDMIDA  682
                    RD+++ ++++    K DG  + VE G     +  KMSKS +N V+P+D+++ 
Sbjct  576  --------RDSRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQ  627

Query  683  YGADTCRLFMMFASPPDMSCEWSDAGVEGANRFLRRVWRL-AHGHVSAGLPGKLDVASLS  741
            YGADT R++ MF +P D S  WS+ G+EG+ +FL RV RL +  +++   +G LD     
Sbjct  628  YGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALD-----  682

Query  742  DEQKAVRRAIHLAIKQASNDIGQHHKFNTAIAQVMTLMNVLEKAATA-TEQDRALVQEGL  800
                   +  + ++K  ++++ ++ KFNTAIAQ+M ++N  +K     ++  +++VQ   
Sbjct  683  -------KVYNETVKAVTEQV-DQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQ---  731

Query  801  EIVTLLLAPITPHISHELWQRLGHADAVID-AQWPQVDESALVQDSLTLVVQVNGKLRGQ  859
                 L+AP++PH+++ELWQ L  ++  I    WP  DES LV++ + +VVQ++GK++++
Sbjct  732  -----LIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAK  786

Query  860  IEVPASASREDVEAAARANENVLRFTEGLSIRKVIVVPGKLVNIVAN  906
            + V+   SRE+++  A ANE+V     G  I KVI VP KLVNIV +
Sbjct  787  LVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

1613) leuS in NC_009436


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  498 bits (1878),  Expect = 7e-142, Method: Compositional matrix adjust.
 Identities = 360/899 (41%), Positives = 540/899 (61%), Gaps = 80/899 (8%)

Query  5    YRPEEIETKVQQHWDEKRTFEVTEDESKEKYYCLSMLPYPSGR-LHMGHVRNYTIGDVIA  63
            Y    IE K Q  W +++TF    D SK K+Y L M+PYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSR  123
            R++R  G NVL+P+GWDAFGLPAE  A+     PA  T +NIA  K Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVI-DGCCWRCDTK  182
            E+ T  P+YY+W Q +FT LY KGL Y    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERKEIPQWFIKITAYADELLRDLDNLDHWPDTVKTMQRNWIGRSEGVEITFNVENSDQK  242
            V RK + QW +KITAYA+ LL DL+++D WP+++K MQRNWIG+S G ++TF+V ++D+ 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LTVYTTRPDTFMGATY--LavaaghplaqqaaannpalaaFI-DECRNTKVAEADMATME  299
            +TV+TTRPDT+ GATY  LA   +   A  ++ +  A+A +  +   ++ +A +D+A  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KE  301

Query  300  KKGVATGFNAIHPLTGEAVPVWAANFVLMEYGTGAVMAVPGHDQRDYEFATKYGLPIKRV  359
            K GV TG  AI+P+ G  +PVW A++VL  YGTGA+MAVP+HD+RD EFA ++ L I  V
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  360  IKSPEQKAYEHALEYGLGSAKNPNDFEPLTHNQRSEFLGLLTAELNKPYLEKDGETYNSG  419
            +                G+  +   F     +  S+FL                      
Sbjct  362  LE---------------GGNVEEAAFTEDGLHINSDFL----------------------  384

Query  420  KFDGLSFEAAFNSIAAALITKGVGERKVNYRLRDWGVSRQRYWGAPIPMVTLEDGTVLPT  479
              DGL   +A+  +   L + GVG+ +V YRLRDW  SRQRYWG PIP++  EDGT  + 
Sbjct  385  --DGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAV  442

Query  480  PEDQLPVILP--EDVVMDGIS-SPIKADPEWAKTT-VNGQPALRETDTFDTFMESSWYYA  535
            PE +LP++LP   D+   G + SP+    +W   T  +G  + RET+T      SSWYY 
Sbjct  443  PESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVKGRRETNTMPQWAGSSWYYL  502

Query  536  RYTCPQYQEGMLDSKAANYWLPVDIYIGGIEHAIMHLLYFRFFHKLMRDAGLVNSDEPAK  595
            RY  P+  E + D    + WLPVDIY+GG EHA++HLLY RF HK++ D G+V + EP +
Sbjct  503  RYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQ  562

Query  596  QLLCQGMVLADAFYYVGVNGERNWVSPVDAIVERDEKGRIVKAKDAAGNELVYTGMSKMS  655
            +L+ QGM+L+ ++      + R  + + D +  RD  G +      +G+EL   + +KMS
Sbjct  563  KLFNQGMILGTSY-----RDSRGALVATDKVEKRD--GSFFHV--ETGEELE-QAPAKMS  612

Query  656  KSKNNGIDPQVMVERYGADTVRLFMMFASPADMTLEWQESGVEGANRFLKRVWKLVYEHT  715
            KS +N ++P+ +VE+YGADT+R++ MF +P D ++ W E G+EG+ +FL RV +L+    
Sbjct  613  KSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKE  672

Query  716  SQGEAPALNVGALSEDQQALRRDVHKTIAKVTDDIGRRQTFNTAIAAIMELMNKLARAPQ  775
               E ++           AL +  + T+  VT+++++ + FNTAIA +M ++N       
Sbjct  673  ITEENSG-----------ALDKVYNETVKAVTEQVDQMK-FNTAIAQLMVFVN-------  713

Query  776  EGEQDRALMREALLAVVRMLNPFTPHACFTLWQELKGEGD-IDNAPWPVADESAMVENTT  834
             ++++  L  +   + V+++ PF+PH    LWQ L + G+ I   PWP  DES +VEN  
Sbjct  714  AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDV  773

Query  835  LVVVQVNGKVRGKITVAVDATEEQVRERAGQEHLVAKYLEGVTVRKVIYVPGKLLNLVV  893
             +VVQ++GKV++K+ VA D + E+++E A  ++ V   + G  + KVI VP KL+N+V+
Sbjct  774  EIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

1614) Olsu_1022 in NC_014363


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  497 bits (1876),  Expect = 1e-141, Method: Compositional matrix adjust.
 Identities = 359/882 (41%), Positives = 530/882 (61%), Gaps = 97/882 (10%)

Query  14   YDAEAIETKWQRVWEDEGLYKTDEDPAKPKRYVLEMFPYPSG-DLHMGHARNYTIGDAMA  72
            YD  AIE KWQ  W D+  +KT+ D++KPK Y L+MFPYPSG +LH+GH+  YT  D ++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  73   RQARMRGFDVLHPMGFDAFGLPAENAAIKHHTQASRWTHQNIAQTVKTMRRMGFSYDYDR  132
            R  R +G +VLHPMG DAFGLPAE+ A+    +++  T +NIA+  + +  +GFSYD DR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  133  MFNTCDPEYYRWGQWMFIKMWERGLAYRATSPVNWCPTCQTVLANEQVV-DGRCWRCGSV  191
              NT DP+YY+W QW+F K+ E+GLAY A  PVNW     T +ANE+V+ DG   R G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  192  PEKRELSQWYLRITDYAQELLGDLDRLDGWPENVKAQQRNWIGRSEGAEIDFALAAEDGV  251
              ++ + QW L+IT YA+ LL DL+ +D WPE++K  QRNWIG+S GA++ F       V
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFK------V  236

Query  252  TPTDRKVTVFTTRADTLFGVSFMllppesalaaelvaGTQCEVAFKELRAATEKVSSVER  311
              TD+  TVFTTR+DTLFG ++ +L+PE AL   + ++ Q E      R A+ K S + R
Sbjct  237  KDTDKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLK-SDLAR  295

Query  312  QGSEREKHGVPTGRYVINPVNGRPVPIWVADYVLMDYGTGAVMGVPCGDQRDFDFAKKYG  371
             +  +EK GV TG Y INPVNG+ +P+W+ADYVL  YGTGA+M+VP  D+RD +FAK++ 
Sbjct  296  TDLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFN  355

Query  372  LEIAPII--CEKDDPLYAELGDERELRIRSVDWDRAMVAEGYLVQSGEFTGLKGGKHSEA  429
            L+I P++   + +++ ++E G    L+I                 +++F  L G   + A
Sbjct  356  LDIIPVLEGGNVEEAAFTEDG----LHI-----------------NSDF--LDGLDKASA  392

Query  430  VDAVVKWLGEHGCGRETVQFRLRDWLISRQRYWGNPIPMIH---CDDCGdvpvpeedlpv  486
            +  +V WL  +G G E V +RLRDWL+SRQRYWG+PIP+IH       +        +  
Sbjct  393  IAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLP  452

Query  487  llpddldlGAGET-LAEYAPFYETTCPRCGRPARRVTDTMDTFTCSSWYYLRYADPHNDN  545
            +  D    G+GE+ LA+ +   E T     + +RR T+TM   + SSWYYLRY DPHN +
Sbjct  453  VTKDIRPSGTGESPLANVTDWLEVTREDGVK-GRRETNTMPQWAGSSWYYLRYIDPHNTE  511

Query  546  LPFSREAARRWMPVDNYIGGIEHAILHLLYSRFWTKVMRDLGMLDVDEPFTNLLCQGMV-  604
                 E  ++W+PVD Y+GG EHA+LHLLY+RFW KV+ DLG++   EPF +L+ QGM+ 
Sbjct  512  KLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMIL  571

Query  605  ----KDEHG----------------------------DTMSKSKGNVVPPSSVIEPYGAD  632
                +D +G                              MSKS  NVV P  V+E YGAD
Sbjct  572  GTSYRDSRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGAD  631

Query  633  TMRLAILFIAPPEKDFDWDPEAVAGANRFIKRAWRVVWTLARSADRGVVLDAAALGPQAR  692
            T+R+  +F++P +  + W  E++ G+ +F+ R  R++      + + +  + ++      
Sbjct  632  TLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLI------TTKEITEENSG------  679

Query  693  ELNRVLHEMGLRCTSDFDRGQFNTAISAVMELVNAASKYANEVSAERRDGALCWRVAHDI  752
             L++V +E     T + D+ +FNTAI+ +M +VNAA+K          ++ L    A ++
Sbjct  680  ALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANK----------EDKLFSDYAKGF  729

Query  753  VAMLAPICPHWAEELHHEALGLAGSVYNEPWPSFDAEQAKSDTIEIAVQVKGKVRARIQV  812
            V ++AP+ PH +EEL +   + + S+   PWPS+D  +   + +EI VQ+KGKV+A++ V
Sbjct  730  VQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVV  789

Query  813  AADSSKDELEAA--AREAVSSQIEGKDVRKVIVVPGRLVNIV  852
            A D S++EL+    A E V ++I GKD+ KVI VP +LVNIV
Sbjct  790  AKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIV  831

1615) leuS in NC_015711


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  497 bits (1876),  Expect = 9e-142, Method: Compositional matrix adjust.
 Identities = 349/861 (41%), Positives = 538/861 (63%), Gaps = 69/861 (8%)

Query  7    YEPQAIEGKWQTRWDDAGIFRAGRRPGAPKKYVLEMLPYPSGK-MHMGHVRNYLLGDVYA  65
            Y+  AIE KWQ+ W D   F++G  ++ PK Y L+M+PYPSG  +H+GH   Y   D+ +
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  66   RYYWMQGFDVLHPLGWDALGLPAENAAIKDGVHPAVRTAENIASFKKEVKSLGYSYDWER  125
            R+ + QG +VLHP+GWDA+GLPAE+ A+  G +PA  TAENIA+FK+++++LG+SYDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  126  EVNTSDPEYYRWNQWFFIQMLERGLVYRRFSKVNWCTGCHTVIANEQV-KDGVCERCDSP  184
            EVNT+DP+YY+W QW+F ++ E+GL Y     VNW     T IANE+V  DG  ER + P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  185  VVDKEMPEWAFRITRYSQELLEALDTLKEWPHRITAAQRNWIGRSDGAEADFRVQGHDAA  244
            VV K M +W ++IT Y++ LLE L+ + +WP+ I   QRNWIG+S GA+  F+V++ D  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  245  LRVFTTRVDTIFGCTYVVLAPDHKLVAQVTTPerraeveafarrmaaQSKTERLGEGTEK  304
            + VFTTR DT+FG TY VLAP+H LV  +TT+++   V  + R+ + +S   R + + EK
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEK  302

Query  305  EGVFTGAYAENPFTGQAVPIWIANFVLSDYGTGAVMSVPAHDERDFAFARKYSLPVKVVI  364
             GV TG+YA NP  G+ +P+WIA++VL+ YGTGA+M+VPAHDERD  FA++++L +  V+
Sbjct  303  TGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL  362

Query  365  QPASGDKLPPGDKLEAAYTEYGVLEDSGAYTGQTSEQARQAMAASLEKDGKGKATVTYRQ  424
            + ++ +        EAA+TE G+  +S+   G     A   M   LE +G G+  VTYR 
Sbjct  363  EGGNVE--------EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRL  414

Query  425  KDWGFSRQRYWGTPIPIVYCEKCDPERQGIPVPMDQLPVRLPEIDTQAVLTGKGEPPLAK  484
            +DW FSRQRYWG PIPI+  E    +  + +VP  +LP+ LP +  +   +G GE+PLA+
Sbjct  415  RDWLFSRQRYWGEPIPIIHWE----DGTSTAVPESELPLVLP-VTKDIRPSGTGESPLAN  469

Query  485  VASWVNTTCPKCGGPARREAETMDTFVDSCWYFARYLSPHYDAAPFDPKEAQRFLPVDIY  544
            V+ W++ T    G  +RRE++TM    +S WY+ RY+ PH      D    ++ LPVDIY
Sbjct  470  VTDWLEVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIY  528

Query  545  VGGPEHAVMHLLYFRFWTRVMKLLGLSPVDEPVTRLITQGIVNGPDAR------------  592
            VGG+EHAV+HLLY RFW +V+  LG+ P  EP  +L+ QG++ G   R            
Sbjct  529  VGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKV  588

Query  593  ---------------------KMSKRWGNVVAPSSIVQKYGADTARAYVLFAGPPERDFD  631
                                 KMSK   NVV P  +V++YGADT R Y +F GP +  + 
Sbjct  589  EKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIA  648

Query  632  WSDDQVEGVFRFLKRVWtlaathqaatatatHDGPYEGKALEIRRAAHKTLKRVGEAIER  691
            WS++ +EG  +FL RV  L +T + +          E ++  + +  + T+K V E +++
Sbjct  649  WSEEGLEGSRKFLDRVYRLITTKEIT----------EENSGALDKVYNETVKAVTEQVDQ  698

Query  692  LSFNTAIAGIMEGVNALYAQGTPetaaekaamaeaVRLLTVVLTPFAPHIADEIAEAYGG  751
            + FNTAIA +M  VNA   ++           ++  + +  +++PFAPH+++E+ +A  +
Sbjct  699  MKFNTAIAQLMVFVNAANKEDK--------LFSDYAKGFVQLIAPFAPHLGEELWQALTA  750

Query  752  KDFTVA-QSWPAFDPALVVDDVIPYAVQVNGKLRAEIRVPadaaeadvraaaeadekvqa  810
             + +++  +WP++D + +V++ +   VQ++GK++A + V+ D +  +++  A A+EKVQA
Sbjct  751  SGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQA  810

Query  811  alaGKTLRKFVFVPKRLVNFV  831
             +AGK + K + VP++LVN+V
Sbjct  811  EIAGKDIIKVIAVPNKLVNIV  831

1616) F750_2393 in NC_021055


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  496 bits (1870),  Expect = 3e-141, Method: Compositional matrix adjust.
 Identities = 359/740 (49%), Positives = 491/740 (67%), Gaps = 60/740 (8%)

Query  229  LAYASDAPVNWAPGLGTVLANEEVTADGRSERGNFPVFKAKLRQWNMRITAYADRLLNDL  288
            LAY ++ PVNW   LGT +ANEEV +DG SERG +PV +  +RQW ++ITAYA+RLL+DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  289  DGLDWPEAIKLQQRNWIGRSEGARVDFPV-DGAGDITVFTTRQDTLFGATYMVLAPEHEL  347
            + +DWPE+IK  QRNWIG+S GA V F V D   D+TVFTTR DTLFGATY VLAPEH L
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  348  VERIIPAAWPEGTHPVWTGGHANPAEAVTAYRKQAAAKSDVERQAEAKDKTGVFTGAYAT  407
            V+ I                 ++ AEAV+ Y++QA+ KSD+ R   AK+KTGV TG+YA 
Sbjct  268  VDAITT---------------SDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAI  312

Query  408  NPVSGEKVPVFIADYVLMGYGTGAIMAVPAHdardfafarafELPMRCVVEPSDDRGLDT  467
            NPV+G  +PV IADYVL +YGTGAIMAVPAHD RD  FA+ F+L +  V+E ++      
Sbjct  313  NPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVE----  368

Query  468  STWEDAFASYEAKLVNSANDEVSLDGLGVVDAKARITEWLQAHGVGEGTVNFRLRDWLFS  527
               E AF+  E  L  +++    LDGL+   A A++ EWL+A+GVG+  V +RLRDWLFS
Sbjct  369  ---EAAFT--EDGLHINSD---FLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  528  RQRYWGEPFPIVYDEEGIAHAlpesmlplelpeveDYSPRTFDPEDADTQPETPLSRNAD  587
            RQRYWGEP+PI+  E+G + A+PES LPL LP   D  P            E+PL+  +D
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTD  472

Query  588  WVNVTLDLGDGSGPRNYRRETNTMPNWAGSCWYELRYLDPHNDQRLVDPAIEQYWMGPRE  647
            W++VT +     G +  RRETNTMP+WAGS WY LRY+DPHN ++L D  + + W+    
Sbjct  473  WLEVTRE----DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWL----  523

Query  648  GQPTGGVDLYVGGAEHAVLHLLYARFWSKVLHDLGHISSAEPFHKLYNQGMIQAFVYRDS  707
                  VD+YVGGAEHAVLHLLYARFW KVL DLG +++ EPF+KL+NQGMI +  YRDS
Sbjct  524  -----PVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDS  578

Query  708  RGIAVPAVEVEERDGAYYH--AGEKVSRVLGKMGKSLKNAVTPDEICGEYGADTLRLYEM  765
            RG  V++  VE RDG+++H  +GE + +  +KM+KSLKN V PD++  +YGADTLR+YEM
Sbjct  579  RGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEM  638

Query  766  AMGPLDVSRPWDTRAVVGQYRLLQRLWRNvvdeetgevtvvdtepgedtLRALHKAIDGV  825
             MGPLD S +W   ++ G  ++L+R+ R +   E  E      +      +  + ++ +V
Sbjct  639  FMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALD------KVYNETVKAV  692

Query  826  GQDMAGMRFNTAIAKITELNNHLTKAGGPLSRSVAERLVLLTAPLAPHVAEELWRRL-GH  884
             +++  M+FNTAIA++  + N   K  + L    A  +V L AP+APH++EELW+ L + 
Sbjct  693  TEQVDQMKFNTAIAQLMVFVNAANKE-DKLFSDYAKGFVQLIAPFAPHLGEELWQALTAS  751

Query  885  TESVVHQDFPVADPAYVVDETVTCVVQIKGKVKARLEISPSITSEELEALALADGNVVAA  944
             ES+     P  D + +V++ V  VVQIKGKVKA+L ++  ++ EEL+ +ALA+ +V A 
Sbjct  752  GESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAE  811

Query  945  LGGAGIRKVIVRAPKLVNIV  964
            ++G +I KVI  + KLVNIV
Sbjct  812  IAGKDIIKVIAVPNKLVNIV  831


 Score =  135 bits (495),  Expect = 2e-32, Method: Compositional matrix adjust.
 Identities = 75/150 (50%), Positives = 101/150 (68%), Gaps = 10/150 (6%)

Query  31   ADIEARWQDFWDAEGTYEAPNPTGDLADGSGLAAKPKRFIMDMFPYPSGAGLHVGHPLGY  90
            + IE++WQ FW  + T+ +             A+KPK + +DMFPYPSGAGLHVGHP GY
Sbjct  7    TAIEPKWQAFWADNHTFKTGTD----------ASKPKFYALDMFPYPSGAGLHVGHPEGY  56

Query  91   IATDVYARHQRMTGHNVLHTLGFDAFGLPAEQYAVQTGTHPRASTEANMENMKVQLRRLG  150
             ATD+ +R +R  GHNVLH +G DAFGLPAEQYA++TG +P   T  N+ N K Q+  LG
Sbjct  57   TATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALG  116

Query  151  LGHDKRRSFATIDAEYYKWTQWIFLQIFNS  180
            ++ D  R   T D++YYKWTQWIF ++++ 
Sbjct  117  FSYDWDREVNTTDPNYYKWTQWIFTKLYEK  146

1617) BAST_0705 in NC_018720


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  496 bits (1872),  Expect = 3e-141, Method: Compositional matrix adjust.
 Identities = 335/752 (45%), Positives = 485/752 (65%), Gaps = 69/752 (9%)

Query  237  LAYISRSPVNWCPGLGTVLANEEVTAEGRSERGNYPVYQRELKQWSMRITAYGHRLLEDL  296
            LAY +  PVNW   LGT +ANEEV ++G SERG YPV ++ ++QW ++ITAY++RLLEDL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  297  DILDWPEKVKLMQRNWIGESHGASVDFTVPSSDGDQTMEVYTTRPDTLFGATFAVVSPEH  356
            + +DWPE +K MQRNWIG S GA+V F V   D D+   V+TTRPDTLFGAT+AV++PEH
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKV--KDTDKDFTVFTTRPDTLFGATYAVLAPEH  265

Query  357  DLLQHLPQEWPDGVPEQWKGGYANPAEGVQAYRRAAEAKTAKDRVDEGGAKTGLFTGLYA  416
             L++ +                ++ AE+V  Y+R A  K+   R D +  KTG+ TG YA
Sbjct  266  ALVDAITT--------------SDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYA  311

Query  417  VNPITGAKLPIFTADYVLMDYGTGAIMAVPGGDQRDYDFAVKYGLPVVYTVSPLAESGQT  476
            +NP+ G  +P+  ADYVL  YGTGAIMAVP+ D+RD +FA ++ L ++    P+ E+G+ 
Sbjct  312  INPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDII----PVLEGGNV  367

Query  477  LDDYRGKAPFVSHDGIVVNSSVKATQAAGDPLSLDGLRVDQAIEKVTEWLESAGVGHGTV  536
                   A+F ++DG+ +NS             LDGL    AI K+ EWLE+ GVG+  V
Sbjct  368  -----EEAAF-TEDGLHINSDF-----------LDGLDKASAIAKMVEWLEAEGVGNENV  410

Query  537  SYRLRDWLFSRQRYWGEPFPVVYDDQGLPHLLPDDQLPVALPDVPDYSPKTFDPEDAQSS  596
            +YRLRDWLFSRQRYWGEP+P++  ++G +  +P+ +LP+ LP   D  P         ++
Sbjct  411  TYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPS--------GT  462

Query  597  PEAPLSRNQDWVNVTLDLGDGPKVYHRDTNTMPNWAGSCWYYMRYIDPKDDQHMVDPEEY  656
             E+PL+   DW++VT +  DG K  +R+TNTMP+WAGS WYY+RYIDP + + + D E  
Sbjct  463  GESPLANVTDWLEVTRE--DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELL  519

Query  657  DYWLGPRHNATAGESGGVDLYVGGVEHAVLHLLYARFWHKVLYDLGYVSSKEPFHKLFNQ  716
              WL             VD+YVGG EHAVLHLLYARFWHKVLYDLG V++KEPF+KLFNQ
Sbjct  520  KQWL------------PVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQ  567

Query  717  GMIQAYAYTDQRGQYVPAAeveeheeggkvgYTWQGQPVNREFGKMGKSLKNIITPDDMY  776
            GMI + +Y D RG  V++  VE ++ +     T  G+ +++  +KM+KSLKN++ PDD+ 
Sbjct  568  GMILGTSYRDSRGALVATDKVEKRDGSFFHVET--GEELEQAPAKMSKSLKNVVNPDDVV  625

Query  777  RTYGADTFRLYEMSMGPLDESRPWNTRNVVGGMRFLQRLWRNVVDEQTGEVVLDEGEPDQ  836
              YGADT+R+YEM MGPLD S +W+   + G+ +FL+R+ R +   +  E   + G  D 
Sbjct  626  EQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITEE--NSGALD-  682

Query  837  KTLKLLNTTIHDVTAEMEAMRPNTAIARMIVLNNHLTGLNPTPRAAIEPLVLMLSPIAPH  896
               K+ N T+  VT +++ M+ NTAIA+++V+ N     +         +V +++P+APH
Sbjct  683  ---KVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPH  739

Query  897  ICEELWSRL-GHNESLAHAQWPTWDDRYLGEDTVTAVVQVKGKVRGKLQVSPDIAPDQLK  955
            + EELW  L +  ES++   WP+ D+  L E+ V  VVQ+KGKV++KL V+ D++ ++L+
Sbjct  740  LGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQ  799

Query  956  AMALALPAVQERLGGKEPRKVIVKAPKIVSVV  987
             +ALA   VQ  ++GK+  KVI  + K+V++V
Sbjct  800  EVALANEKVQAEIAGKDIIKVIAVPNKLVNIV  831


 Score =  130 bits (477),  Expect = 4e-31, Method: Compositional matrix adjust.
 Identities = 73/151 (49%), Positives = 106/151 (71%), Gaps = 12/151 (7%)

Query  29   TIEERWQQRWDKEGTFWAANTKGDLTDAQGEHAGGRSPYFVIDMFPYPSGKGLHVGHPLG  88
            +IE +WQ  W  + TF            +    ++++ ++ +DMFPYPSG GLHVGHP G
Sbjct  8    AIEPKWQAFWADNHTF------------KTGTDASKPKFYALDMFPYPSGAGLHVGHPEG  55

Query  89   YIATDVVSRYHRMKGENVLHAMGYDAFGLPAEQYAVQTGQHPRVTTEQNIANMRWQLHRL  148
            Y ATD++SR+ R +G+NVLH+MG DAFGLPAEQYA++TG++P   T +NIAN ++Q++ L
Sbjct  56   YTATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINAL  115

Query  149  GLSFDDRRSFATIDTDYVRWTQWIFSRIYES  179
            G+S+D  R   T D +Y +WTQWIF+++YE 
Sbjct  116  GFSYDWDREVNTTDPNYYKWTQWIFTKLYEK  146

1618) Ornrh_0971 in NC_018016


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  496 bits (1871),  Expect = 3e-141, Method: Compositional matrix adjust.
 Identities = 324/743 (44%), Positives = 495/743 (67%), Gaps = 61/743 (8%)

Query  205  LTYLAEAEVNWCPALGTVLANDEVI-NGLSERGGHPVVRKKMRQWMMRITAYAERLLNGI  263
            L+Y AE  VNW   LGT +AN+EV+ +G SERGG PVVRK MRQWM++ITAYAERLL+++
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  264  EYNEQDLEWTDALKESQKYWIGKSKGASVKFKVKGQENTEIEVFTTRPDTIFGVSFMVLA  323
            E    +++W +++K+ Q+ WIGKS GA+V FKVK+ ++ ++ VFTTRPDT+FG ++ VLA
Sbjct  208  E----EVDWPESIKDMQRNWIGKSTGANVTFKVKDTDK-DFTVFTTRPDTLFGATYAVLA  262

Query  324  PEHDLVQQLTTPAQKEAIDAYIEETAKRSERERMAEVKRVTGVFTGAYAINPISGKEVPI  383
            PEH LV+ +TT+ Q EA+  Y  +++ +S+  R    K  TGV TG+YAINP++GKE+P+
Sbjct  263  PEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAINPVNGKEMPV  322

Query  384  WIADYVLAGYGTGAVMAVPAGDERDYAFAKTFDLSIENIFEGVDISEQAFTDKTAKVPLQ  443
            WIADYVLA+YGTGA+MAVPA DERD  FAK F+L I  ++EG ++ E AFT+    +   
Sbjct  323  WIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEAAFTEDGLHI---  379

Query  444  NSDFLNGLTVKEAMNKAIEKIESLGVGKAKINYRLRDAVFSRQRYWGEPVP-IYFNQGIP  502
            NSDFL+GL    A+ K +E +E+ GVG+ ++ YRLRD +FSRQRYWGEP+P I  ++G +
Sbjct  380  NSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTS  439

Query  503  QSIGEEHLPLVLPEVSEYLPTETGEPPLGRATQWAWDIEKNQVVENSLIDEKTVFPLELN  562
             ++ E +LPLVLP   +  P+ TGE+PL+  T+W  ++ +++ V             E N
Sbjct  440  TAVPESELPLVLPVTKDIRPSGTGESPLANVTDWL-EVTREDGVKGR---------RETN  489

Query  563  TMPGWAGSSWYQFRYMDPQNEDALASDEALKYWQNVDLYLGGSEHATGHLLYSRFWTKFL  622
            TMP WAGSSWY +RY+DP+N + LA +E LK W  VD+Y+GG+EHA  HLLY+RFW K L
Sbjct  490  TMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWHKVL  549

Query  623  KDRGFVSSEEPFKKLINQGMILGESAFVHRVNNTNQYVSADKLEGYETTPVHADVSFVSG  682
             D G V++ EPF+KL+NQGMILG S    R ++    V++DK+E  + +  H + +    
Sbjct  550  YDLGVVPTKEPFQKLFNQGMILGTS---YR-DSRGALVATDKVEKRDGSFFHVETG----  601

Query  683  NNVLDTQAFKNWRDDLKDAEFIVSDDGKFYVSREVEKMSKSKFNVVNPDDICNEYGADTL  742
                         ++L +A                 KMSKS  NVVNPDD+ ++YGADTL
Sbjct  602  -------------EELEQAP---------------AKMSKSLKNVVNPDDVVEQYGADTL  633

Query  743  RMYEMFLGPIEQSKPWITNGLSGVNGFIKKLWRLFFKNDELQVVDAPASKEELKVLHTLI  802
            R+YEMF+GP++ S +W  +GL G   F+ ++ RL+  ++   + +  ++  + KV +  +
Sbjct  634  RVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKE---ITEENSGALD-KVYNETV  689

Query  803  QKVTDDIENFSFNTSVSAFMIAVNDLQKLQCNKAEILSPLVILLSPFAPHIAEELWHVL-  861
            + VT+++++  FNT+++ +M+ VN  +K +   ++    +V L++PFAPH++EELW+ L 
Sbjct  690  KAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALT  749

Query  862  GNEDSVTRQPYPIFEEKYLKEDNKEYPISFNGKMRFTLSLPLDLSKEEIEKAVMEEPQTA  921
            ++ +S++  P P ++E  L E++ E  + ++GK++  L ++ DLS+EE++   + + +  
Sbjct  750  ASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQ  809

Query  922  KYLEGKNPKKIIVVPGKIVNIVM  944
              + GK+  K+I VP K+VNIV+
Sbjct  810  AEIAGKDIIKVIAVPNKLVNIVI  832


 Score =  184 bits (682),  Expect = 3e-47, Method: Compositional matrix adjust.
 Identities = 88/142 (62%), Positives = 118/142 (84%), Gaps = 0/142 (0%)

Query  3    YQPNQIEPKWQKFWAENRIYEAENHSDKPKFYVLDMFPYPSGAGLHVGHPLGYIASDIYA  62
            Y+   IEPKWQ FWA+N+ + +  ++ KPKFY LDMFPYPSGAGLHVGHP GY A+DI +
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRHKGFNVLHPMGYDSFGLPAEQYAIQTGQHPAITTKENIARYREQLDKIGFSFDWDR  122
            R+KR +G NVLHPMG D+FGLPAEQYA++TG++PA  T ENIA ++ Q++ +GFS+DWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EIRTSNPDYYRWTQWIFLQLFD  144
            E+ T++P+YY+WTQWIF +L++
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYE  145

1619) leuS in NC_010407


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  496 bits (1870),  Expect = 3e-141, Method: Compositional matrix adjust.
 Identities = 353/874 (41%), Positives = 514/874 (59%), Gaps = 83/874 (9%)

Query  13   YDFRAIEAEWSEVWEREQPFRTPDASDSRPRKYILDMFPYPSG-DLHMGHAEAFALGDAV  71
            YD  AIE+ W   W  ++ F+T ++  S+P+ Y LDMFPYPSG +LH+GH+E+++  D +
Sbjct  4    YDHTAIEPKWQAFWADNHTFKT-GTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDIL  62

Query  72   ARYWRQQGFNVLHPIGWDSFGLPAENAAIKRGVDPREWTYANIETQKQSMKRYGLSFDWE  131
            +R+ R QG NVLHP+GWD+FGLPAE+ A+  G DP E T  NI   K+ ++  G+S+DW+
Sbjct  63   SRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWD  122

Query  132  RELHTSDPEYYRWNQWLFLKMHEKGLAYRKDSWVNWDPVDQTVLANEQVLPDGTSDRSGA  191
            RE++T+DP+YY+W QW+F K+ EKGLAY  +  VNW     T +ANE+VLPDGTS+R+G 
Sbjct  123  REVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGY  182

Query  192  VVVKKKLTQWYLRITDYADRLVDDLNQLEGTWPAKVLSMQRNWIGRSIGAEVDFVVEGRD  251
             VV+K + QW L+IT YA+RL++DL++++  WP  +  MQRNWIG+S GA+V F V + D
Sbjct  183  PVVRKPMRQWMLKITAYAERLLEDLEEVD--WPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  252  EPVTVFTTRPDTLHGATFMVVAPDSDLAAELVEGASEEVRESFRGYLERTQRLN-EIERS  310
               TVFTTRPDTL GAT+ V+AP+  L   +  +   E    ++    R   L+ ++ R+
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYK----RQASLKSDLART  296

Query  311  TTDRPKTGIPLGLTAINPVNGERIPVWAADYVLADYGTGAVMAVPAHDQRDLDFARAFDL  370
               + KTG+  G  AINPVNG  +PVW ADYVLA YGTGA+MAVPAHD+RD +FA+ F+L
Sbjct  297  DLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNL  356

Query  371  PVRVVVDTTQPVTGAIRIIPEDGELPDLEEVLPGRTGVALPGEGRLINSGSLNGLSKQPA  430
             +  V+              E+G++ +           A+  +G  INS+ L+GL K +A
Sbjct  357  DIIPVL--------------EGGNVEE----------AAFTEDGLHINSDFLDGLDKASA  392

Query  431  IKRVIEQLEAEGRGRAAKNYRLRDWLISRQRFWGTPIPIVYDAEGSEIRVPEDQLPVRLP  490
            I +++E LEAEG G     YRLRDWL+SRQR+WG PIPI+   +G+   VPE +LP+ LP
Sbjct  393  IAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLP  452

Query  491  DTEGLDLTPKGKSPLAAATAWSNVPSPVDGSPATRDPDTMDTFMDSSWYWLRFLSPNDAT  550
             T ++  +  G SPLA  T W +V    DG  + R+ +TM    +SSWY LR++ P+++ 
Sbjct  453  VTKDIRPSGTGESPLANVTDWLEVTRE-DGVKGRRETNTMPQWAGSSWYYLRYIDPHNTE  511

Query  551  KAFDPADADRWAPIDQYVGGVEHAILHLLYSRFITKVLFDLGYVTFTEPFSALLNQGMVL  610
            K  D     +W P+D YVGG EHA+LHLLY+RF  KVL+DLG V   EPF  L+NQGM+L
Sbjct  512  KLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMIL  571

Query  611  sggskmskskg--------------gVDLGSEMD---------------------RHGVD  635
            + + + S++                 V+ G E++                     + G D
Sbjct  572  GTSYRDSRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGAD  631

Query  636  AIRLTMAFAGPPEDDIDWEDVSPSGSAKFLARAWRLTGDITSAPEVEWKTGDEALRRVTH  695
            ++R+   F GP +  I W + +  GS KFL R  RL      + E        AL +V +
Sbjct  632  TLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITEE-----NSGALDKVYN  686

Query  696  RFLAEAPGMLEAFKFNVVIARTMELVNAIRKTIDQGPGGGDaavreatevvavaLSLFAP  755
              +      ++  KFN  IA+ M +VNA  K         D    + +      ++ FAP
Sbjct  687  ETVKAVTEQVDQMKFNTAIAQLMVFVNAANK--------EDKLFSDYAKGFVQLIAPFAP  738

Query  756  YTAEDMWKRLGREG-SVAFAGWRKADRNLLvqttvtavvqvDGKVRDKLEVDAKIGADEL  814
              +E++W+ L   G S+++  W   D + LV+  V  VVQ+ GKV+ KL V   ++ +EL
Sbjct  739  HLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREEL  798

Query  815  EALARETAGVRRSTAGRTIDKVIVRAPKIVSITT  848
            + +A     V+   AG+ I KVI  + K+V+I  
Sbjct  799  QEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

1620) Sfla_4314 in NC_016114


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  495 bits (1867),  Expect = 6e-141, Method: Compositional matrix adjust.
 Identities = 358/740 (49%), Positives = 492/740 (67%), Gaps = 60/740 (8%)

Query  220  LAYASDAPVNWAPGLGTVLANEEVTADGRSERGNFPVFKAKLRQWNMRITAYADRLLNDL  279
            LAY ++ PVNW   LGT +ANEEV +DG SERG +PV +  +RQW ++ITAYA+RLL+DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  280  DGLDWPEAIKLQQRNWIGRSEGARVDFPV-DGAGDITVFTTRQDTLFGATYMVLAPEHEL  338
            + +DWPE+IK  QRNWIG+S GA V F V D   D+TVFTTR DTLFGATY VLAPEH L
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  339  VERIIPAAWPEGTHPVWTGGHANPAEAVTAYRKQAAAKSDVERQAEAKDKTGVFTGAYAT  398
            V+ I                 ++ AEAV+ Y++QA+ KSD+ R   AK+KTGV TG+YA 
Sbjct  268  VDAITT---------------SDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAI  312

Query  399  NPVSGEKVPVFIADYVLMGYGTGAIMAVPAHdardfafarafELPMRCVVEPSDDRGLDT  458
            NPV+G  +PV IADYVL +YGTGAIMAVPAHD RD  FA+ F+L +  V+E ++      
Sbjct  313  NPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVE----  368

Query  459  STWEDAFASYEAKLVNSANDEVSLDGLGVVDAKARITEWLQAHGVGEGTVNFRLRDWLFS  518
               E AF+  E  L  +++    LDGL+   A A++ EWL+A+GVG+  V +RLRDWLFS
Sbjct  369  ---EAAFT--EDGLHINSD---FLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  519  RQRYWGEPFPIVYDEEGIAHAlpesmlplelpeveDYSPRTFDPEDADTQPETPLSRNAD  578
            RQRYWGEP+PI+  E+G + A+PES LPL LP   D  P            E+PL+  +D
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTD  472

Query  579  WVNVTLDLGDGSGPRNYRRETNTMPNWAGSCWYELRYLDPHNDQRLVDPAIEQYWMGPRE  638
            W++VT +     G +  RRETNTMP+WAGS WY LRY+DPHN ++L D  + + W+    
Sbjct  473  WLEVTRE----DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWL----  523

Query  639  GQPTGGVDLYVGGAEHAVLHLLYARFWSKVLHDLGHISSAEPFHKLYNQGMIQAFVYRDS  698
                  VD+YVGGAEHAVLHLLYARFW KVL DLG +++ EPF+KL+NQGMI +  YRDS
Sbjct  524  -----PVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDS  578

Query  699  RGIAVPAVEVEERDGAYYH--AGEKVSRVLGKMGKSLKNAVTPDEICGEYGADTLRLYEM  756
            RG  V++  VE RDG+++H  +GE + +  +KM+KSLKN V PD++  +YGADTLR+YEM
Sbjct  579  RGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEM  638

Query  757  AMGPLDVSRPWDTRAVVGQYRLLQRLWRNvvdeetgevtvvdtepgedtLRALHKAIDGV  816
             MGPLD S +W   ++ G  ++L+R+ R +   E  E      +      +  + ++ +V
Sbjct  639  FMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALD------KVYNETVKAV  692

Query  817  GQDMAGMRFNTAIAKITELNNHLTKAGGPLSRSVAERLVLLTAPLAPHVAEELWRRL-GH  875
             +++  M+FNTAIA++  + N   K  + L    A  +V L AP+APH++EELW+ L + 
Sbjct  693  TEQVDQMKFNTAIAQLMVFVNAANKE-DKLFSDYAKGFVQLIAPFAPHLGEELWQALTAS  751

Query  876  SESVVHQDFPVADPAYVVDETVTCVVQIKGKVKARLEISPSITDEELEALALADGNIVAA  935
            +ES+     P  D + +V++ V  VVQIKGKVKA+L ++  ++ EEL+ +ALA+ ++ A 
Sbjct  752  GESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAE  811

Query  936  LGGAGIRKVIVRAPKLVNIV  955
            ++G +I KVI  + KLVNIV
Sbjct  812  IAGKDIIKVIAVPNKLVNIV  831


 Score =  135 bits (494),  Expect = 2e-32, Method: Compositional matrix adjust.
 Identities = 75/150 (50%), Positives = 101/150 (68%), Gaps = 10/150 (6%)

Query  22   ADIEARWQDFWDAEGTYEAPNPTGDLADGSGLAAKPKRFIMDMFPYPSGAGLHVGHPLGY  81
            + IE++WQ FW  + T+ +             A+KPK + +DMFPYPSGAGLHVGHP GY
Sbjct  7    TAIEPKWQAFWADNHTFKTGTD----------ASKPKFYALDMFPYPSGAGLHVGHPEGY  56

Query  82   IATDVYARHQRMTGHNVLHTLGFDAFGLPAEQYAVQTGTHPRASTEANMENMKVQLRRLG  141
             ATD+ +R +R  GHNVLH +G DAFGLPAEQYA++TG +P   T  N+ N K Q+  LG
Sbjct  57   TATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALG  116

Query  142  LGHDKRRSFATIDAEYYKWTQWIFLQIFNS  171
            ++ D  R   T D++YYKWTQWIF ++++ 
Sbjct  117  FSYDWDREVNTTDPNYYKWTQWIFTKLYEK  146

1621) leuS in NC_020546


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  493 bits (1859),  Expect = 2e-140, Method: Compositional matrix adjust.
 Identities = 335/754 (45%), Positives = 486/754 (65%), Gaps = 73/754 (9%)

Query  231  LAYISKSPVNWCPGLGTVLANEEVTAEGRSERGNYPVFQRELRQWSMRITAYGHRLIQDL  290
            LAY +  PVNW   LGT +ANEEV ++G SERG YPV ++ +RQW ++ITAY++RL++DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  291  DTIDWPEKVKLMQRNWIGESHGAAVHFPVASEDGEQDMEVYTTRPDTLFGTTFAVVSPEH  350
            + +DWPE +K MQRNWIG S GA V F V   D ++D  V+TTRPDTLFG+T+AV++PEH
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKV--KDTDKDFTVFTTRPDTLFGATYAVLAPEH  265

Query  351  ELLEHVPAAWPQDVPEAWKGGYATPKEAVHAYRLAAEAKTAKDRVDEGGEKTGLFTGLYA  410
             L++ + +              +   EAV  Y+  A  K+   R D + EKTG+ TG YA
Sbjct  266  ALVDAITT--------------SDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYA  311

Query  411  TNPITGKQLPIFTADYVLMDYGTGAIMAVPGGDQRDYDFAAKFGLPVIYTVKPLPGSNDD  470
             NP+ GK++P+  ADYVL  YGTGAIMAVP+ D+RD +FA +F L +I     L G+N +
Sbjct  312  INPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDII---PVLEGGNVE  368

Query  471  LANYEGKAPFVSHDGIVVNSSTDSTYAKGDSLSLDGLRVDEAIDKAIGWLEAAGVGKGTV  530
             A +       ++DG+ +NS             LDGL    AI K + WLEA GVG+  V
Sbjct  369  EAAF-------TEDGLHINSD-----------FLDGLDKASAIAKMVEWLEAEGVGNENV  410

Query  531  SYRLRDWLFSRQRYWGEPFPIVYDEDEVPHLLPDSMLPINLPDVPDYSPKTFDPEDAESN  590
            +YRLRDWLFSRQRYWGEP+PI+  ED  +  +P+S LP+ LP   D  P         + 
Sbjct  411  TYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPS--------GT  462

Query  591  PEAPLSRNDDWVNITLDLGDGPKQYHRDTNTMPNWAGSCWYYMRYIDPKDAEHMVETDEF  650
             E+PL+   DW+++T +  DG K  +R+TNTMP+WAGS WYY+RYIDP ++E + + + +
Sbjct  463  GESPLANVTDWLEVTRE--DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELL  519

Query  651  NYWMGPHHNKTAGESGGVDLYIGGVEHAVLHLLYSRFWHKVLYDLGYVSSPEPFHKLFNQ  710
            + W+             VD+Y+GG EHAVLHLLY+RFWHKVLYDLG V++ EPF+KLFNQ
Sbjct  520  KQWL------------PVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQ  567

Query  711  GMIQAYAYTDDRGQYVPADEVEEGPAGPDGEPTFTWHGQHANREFGKMGKSLKNIVTPDY  770
            GMI + +Y D RG  V++D VE   ++     T    G++ ++  +KM+KSLKN+V PD 
Sbjct  568  GMILGTSYRDSRGALVATDKVEKRDGSFFHVET----GEELEQAPAKMSKSLKNVVNPDD  623

Query  771  MYENYGADTFRLYEMSMGQLDESRPWNTRNVIGGMRFLQRLWRNVVDENTGEVKVSDDPM  830
            + E+YGADT+R+YEM MG LD S +W+   + G+ +FL+R+ R +   +  E +   +++
Sbjct  624  VVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITEEN--SGAL  681

Query  831  DEKTLKLLNNTIADVTVEMENMRPNTAIAKLIVLNNHLTGLKAVPRAAVEPLILMLSPIA  890
            D    K+ N+T+  VT ++++M+ NTAIA+L+V+ N       +       ++ +++P+A
Sbjct  682  D----KVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFA  737

Query  891  PHICEELWNRL-GHAESLAHEPWPKADERYVGQDTVTAVVQIKGKIRAKLEVSPDIAPEE  949
            PH+ EELW+ L + +ES++  PWP  DE  + ++ V  VVQIKGK++AKL V+ D++ EE
Sbjct  738  PHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREE  797

Query  950  LEKRAL--EAVADRLGGKEPRKVIVKAPKIVSIV  981
            L+  AL  E V   ++GK+  KVI  + K+V+IV
Sbjct  798  LQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIV  831


 Score =  136 bits (499),  Expect = 8e-33, Method: Compositional matrix adjust.
 Identities = 75/150 (50%), Positives = 106/150 (71%), Gaps = 12/150 (8%)

Query  23   TIEEKWQKTWEEQGTFWAANVKGDLTDGNGKNADGRTPYFAMDMFPYPSGKGLHVGHPLG  82
            +IE KWQ  W ++ TF            +     ++  ++A+DMFPYPSG GLHVGHP G
Sbjct  8    AIEPKWQAFWADNHTF------------KTGTDASKPKFYALDMFPYPSGAGLHVGHPEG  55

Query  83   YLATDVVSRYHRMKGENVLHAMGYDAFGLPAEQYAVQTGQHPRVTTEQNIANMSRQLHRM  142
            Y ATD++SR+ R +G+NVLH+MG DAFGLPAEQYA++TG++P   T +NIAN  RQ++ +
Sbjct  56   YTATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINAL  115

Query  143  GLSFDNRRSFATIDPDYMRWTQWIFSRIYD  172
            G+S+D  R   T DP+Y +WTQWIF+++Y+
Sbjct  116  GFSYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1622) Psefu_3459 in NC_015556


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  493 bits (1860),  Expect = 2e-140, Method: Compositional matrix adjust.
 Identities = 360/883 (41%), Positives = 553/883 (63%), Gaps = 76/883 (8%)

Query  5    YQPREIEAAAQSHWDAQNSFAVSEQPGKDTFYCLSMFPYPSGK-LHMGHVRNYTIGDVIA  63
            Y+   IE+  Q+ W  +++F  + +++K  FY L MFPYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMQGKNVLQPMGWDAFGMPAENAAMKNNVAPAKWTYENIAYMKSQLKSLGLAIDWSR  123
            R++R QG NVL+PMGWDAFG+PAE+ AM     PA  T ENIA  K Q+++LG++ DW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVTTCKPDYYRWEQWLFTRLFEKGVIYRKNGTVNWDPVDQTVLANEQVI-DGRGWRSGAV  182
            EV T  P+YY+W QW+FT+L+EKG+ Y  +  VNW     T +ANE+V+ DG + R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  IEKREIPMYYFKITAYAdellssldeldGWPEQVKTMQRNWIGKSRGMEVQFPYNVDSIG  242
            + ++ +    +KITAYA E L    E  +WPE +K MQRNWIGKS G +V F  +V   +
Sbjct  184  VVRKPMRQWMLKITAYA-ERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTF--KVKDTD  240

Query  243  EAGALKVFTTRPDTLMGATYVAVAAEHPL-ATLAANENPELQAFIAECKAGSVAEADMA-  300
                + VFTTRPDTL GATY  +A+EH+L  ++++++++E    +A+ K  +   +D+A 
Sbjct  241  K--DFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEA---VADYKRQASLKSDLAR  295

Query  301  ---TQEKKGLPTSLFVEHPLTGEKLPVWVANYVLMHYGDGAVMAVPAHDERDFAFARKYH  357
               ++EK G+ T+ +  +P+ G  +PVW+A+YVL  YG GA+MAVPAHDERD  FA++++
Sbjct  296  TDLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFN  355

Query  358  LPVKAVVRTSAGDEVGSEWQDAYGEHGQLINSGEFDGLDFEGAFDAIEAALIRKELGKSR  417
            L + +V+  +  +E       A+ E+G  INS+ +DGLD  +A+  +   L    +G+  
Sbjct  356  LDIIPVLEGGNVEE------AAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNEN  409

Query  418  TQFRLRDWGISRQRYWGCPIPIIHCDSCGDVPVPEDQlpvvlpedvvpdGAG---SPLAR  474
              +RLRDW +SRQRYWG PIPIIH +     +VPE +LP+VLP       +G   SPLA 
Sbjct  410  VTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLAN  469

Query  475  MPEFYKCSCPKCGAPAKRETDTMDTFVESSWYFARYASPHYTGGMVDPVAANHWLPVDQY  534
            + +    +    G  ++RET+TM     SSWY+ RY  PH T  + D    ++WLPVD Y
Sbjct  470  VTDWLEVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIY  528

Query  535  IGGIEHAILHLLYARFFHKLMRDEGLLTSNEPFKNLLTQGMVVAETYYRVLENGGKDWFN  594
            +GG EHA+LHLLYARF HK++ D G++ ++EPF++L+ QGM+++ +Y             
Sbjct  529  VGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY-------------  575

Query  595  PADVEVERDAKGKVIAAKL--KSDG--LPVEIG-----GTEKMSKSKNNGVDPQDMIDAY  645
                   RD++G ++A+    K DG  + VE G     +  KMSKS +N V+P+D+++ Y
Sbjct  576  -------RDSRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQY  628

Query  646  GADTCRLFMMFASPPDMSCEWSDAGVEGANRFLRRVWRL-AQGHVSQGLPGVLDIAKLDD  704
            GADT R++ MF +P D S  WS+ G+EG+ +FL RV RL +  ++++  +G LD      
Sbjct  629  GADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALD------  682

Query  705  AGKDIRRAIHLAIKQASQDVGQHHKFNTAIAQVMTLMNVLEKAPQDTDQQRALIQEGLET  764
                  +  + ++K  +++V ++ KFNTAIAQ+M ++N        ++++  L+ +    
Sbjct  683  ------KVYNETVKAVTEQV-DQMKFNTAIAQLMVFVN-------AANKEDKLFSDYAKG  728

Query  765  VALLLAPITPHICHELWQEL-GHEEAIIDASWPVVDESALVQDSLTLVIQVNGKLRGQIE  823
               L+AP++PH+ +ELWQ L +  E+I   +WP  DES LV++ + +V+Q++GK+++++ 
Sbjct  729  FVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLV  788

Query  824  VPADasreaveaaarsnenvQRFTEGLTIRKVIVVPGKLVNIV  866
            V+ D SRE ++  A +NE+VQ    G  I KVI VP KLVNIV
Sbjct  789  VAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIV  831

1623) SCD_n00053 in NC_022357


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  493 bits (1859),  Expect = 2e-140, Method: Compositional matrix adjust.
 Identities = 351/869 (41%), Positives = 532/869 (62%), Gaps = 86/869 (9%)

Query  5    YLPTEIERQTQVFWDQSNAFKAVEISDKPKYYCLSMFPYPSGK-LHMGHVRNYTIGDVLA  63
            Y  T IE + Q FW ++++FK+   + KPK+Y L MFPYPSG  LH+GH   YT  D+L+
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYHRFQGFNVLQPMGWDAFGLPAENAAIQNKVAPAAWTYSNIDYMRGQLKSLGLAIDWSR  123
            R+ R QG NVL+PMGWDAFGLPAE+ A++    PA  T  NI   + Q+++LG++ DW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCKPDYYKWEQWLFTKLFEKGLIYKKLATVNW-DPVDMTVLANEQVIDGCGWRSGAP  182
            E+ T  P+YYKW QW+FTKL+EKGL Y     VNW + ++ ++  +E + DG + R+G P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VEKREIPMYFMKITAYAEELLADLDKLTGWPEQVRTMQKNWIGKSFGAEVHFPYAENAGS  242
            V ++ +    +KITAYAE LL DL+ + +WPE ++ MQ+NWIGKS GA+V F   +    
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  SHPSLLTPHPVLKVYTTRPDTLMGATYvavaaehplaaeaaQGNSELAAFIEECKHGSVA  302
                       + V+TTRPDTL GATY  +A+EH+L        S+ A  + + K+ +  
Sbjct  243  -----------FTVFTTRPDTLFGATYAVLAPEHALVDAI--TTSDQAEAVADYKRQASL  289

Query  303  EADMA----TMEKKGLPTGRFVTHPLNGEKLPVWVANYVLMGYGEGAVMAVPAHDERDFA  358
             +D+A    + EK G+ TG +  +P+NG  +PVW+A+YVL +YG GA+MAVPAHDERD  
Sbjct  290  KSDLARTDLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWE  349

Query  359  FAAKYGLPVRAVIRTSAGDVAPAPWQDAYAEHGVCVNSGKYDGLDFSQASDAIAADLEAR  418
            FA ++ L + +V+   +G+V     + A++E+G+ +NS+  DGLD + A   +   LEA 
Sbjct  350  FAKQFNLDIIPVL--EGGNVE----EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAE  403

Query  419  SLGAKRTQFRLRDWGISRQRYWGCPIPIIHCASCGDVPVPEKDLPVVLPEDVKIDIG---  475
            ++G     +RLRDW +SRQRYWG PIPIIH       +VPE +LP+VLP    I  +   
Sbjct  404  GVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTG  463

Query  476  -SPIKKMPSFYETTCPKCGGPAERETDTMDTFVESSWYYARYTCPDNDQAMLDER-ANYW  533
             SP+ ++    E T    G  + RET+TM     SSWYY RY  P+N + + DE   + W
Sbjct  464  ESPLANVTDWLEVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQW  522

Query  534  LPVDQYIGGIEHAILHLLYARFFNKLMRDVGLVNCDEPFTQLLTQGMVL-----------  582
            LPVD Y+GG EHA+LHLLYARF +K++ D+G+V   EPF +L+ QGM+L           
Sbjct  523  LPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGAL  582

Query  583  --------KDGT---------------KMSKSKGNTVDPQALIDQYGADTARLFMMFAAP  619
                    +DG+               KMSKS  N V+P+ +++QYGADT R++ MF +P
Sbjct  583  VATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGP  642

Query  620  PEQSLEWSDAGVEGAFRFLKRLWKAVHDHIEKGVVEGFKGGDLSAELKALRFQLHGTIQK  679
             + S+ WS+ G+EG+ +FL R+ + +     K + E  ++G L           + T++ 
Sbjct  643  LDASIAWSEEGLEGSRKFLDRVYRLI---TTKEITEE-NSGALDK-------VYNETVKA  691

Query  680  VSDDYGRRQQFNTAIAAVMELMNALAKSGDDSPAGRAVMqealeaavqllaPIVPHVCQA  739
            V+++ ++  +FNTAIA +M ++NA  K +        +  +   + VQL+AP+ PH+ + 
Sbjct  692  VTEQVDQM-KFNTAIAQLMVFVNAANKEDK-------LFSDYAKGFVQLIAPFAPHLGEE  743

Query  740  LWAELKDGANLLD-APWPQVDAVALVQDEIELVLQVNGKLRGSIAVAKDASKEAIEQLAL  798
            LW  L  +++ +   PWP  D   LV++++E+V+Q++GK+++ + VAKD S+E ++++AL
Sbjct  744  LWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVAL  803

Query  799  ANPNVQKFMEGKPAKKIVVVPGRLVNVVI  827
            AN +VQ  + GK   K++ VP +LVN+VI
Sbjct  804  ANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

1624) leuS in NC_008726


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  493 bits (1858),  Expect = 3e-140, Method: Compositional matrix adjust.
 Identities = 354/747 (48%), Positives = 494/747 (67%), Gaps = 65/747 (8%)

Query  227  RRLVYLADSVVNWCPGLGTVLANEEVTSDGRSERGNFPVFRKRLRQWMMRITAYSDRLLE  286
            + L Y A+  VNW   LGT +ANEEV +DG SERG +PV RK +RQWM++ITAY++RLLE
Sbjct  146  KGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLE  205

Query  287  DLDVLDWPDKVKTMQRNWIGRSTGASVEFGTDAGDIE--VFTTRPDTLFGATYMVLAPEH  344
            DL+ +DWP+ +K MQRNWIG+STGA+V F     D +  VFTTRPDTLFGATY VLAPEH
Sbjct  206  DLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEH  265

Query  345  DLVDRLVADQWPADVDARWTFGAATPREAVAAYRASIAAKSDLERQE-NKAKTGVFIGAY  403
             LVD               ++ ++   EAVA Y+   + KSDL R +  K KTGV  G+Y
Sbjct  266  ALVD---------------AITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSY  310

Query  404  ATNPANAKQVPVFIADYVLAGYGTGAIMAVPGGDQRDWDFATEFGLPIIEVVRPVADRPG  463
            A NP N+K++PV IADYVLA+YGTGAIMAVP+ D+RDW+FA +F L II V+        
Sbjct  311  AINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL--------  362

Query  464  EDTGAGGDVSQAAYTGDGVMVNSGFLDGMDVSAAKEAMTERLSADGRGRERVEYKLRDWL  523
                 GG+V +AA+T DG+ +NS+FLDG+D ++A   M E+L A+G G E V Y+LRDWL
Sbjct  363  ----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWL  418

Query  524  FARQRYWGEPFPIVYDADDRAHGlpeellpvelpdvpdYSPVLFdpddadsepsppLAKA  583
            F+RQRYWGEP+PI+   D+ + ++PE  LP+ LP   D  P         +   +PLA+ 
Sbjct  419  FSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANV  470

Query  584  TEWVNVELDLG-DGRKRYTRDTNVMPQWAGSSWYELRYADPHNTEALCAKENEAYWMGPR  642
            T+W++V  + G  GR    R+TN MPQWAGSSWY LRY DPHNTE L   E    W+   
Sbjct  471  TDWLEVTREDGVKGR----RETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWL---  523

Query  643  PAEHGPDDPGGVDLYVGGVEHAVLHLLYSRFWHKVLYDLGHVSSREPYRRLVNQGYIQAF  702
                       VD+YVGG EHAVLHLLY+RFWHKVLYDLG V+++EP+++L NQG I + 
Sbjct  524  ----------PVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGT  573

Query  703  AYTDARGSYVPAAEVVERDGKFFWPGPDGEIEVNQEFGKIGKSLKNSVSPDEICDDYGAD  762
            +Y D+RG+ V++  V  RDG FF    +   E++Q  +K++KSLKN V+PD++ ++YGAD
Sbjct  574  SYRDSRGALVATDKVEKRDGSFF--HVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGAD  631

Query  763  TLRVYEMSMGPLEASRPWATKDVVGAHRFLQRVWRLvvseetgetvvtDDALDEDTLRLL  822
            TLRVYEM MGPL+AS +W+  ++ G+++FL+RV RL        T    +ALD    ++ 
Sbjct  632  TLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRL--ITTKEITEENSGALD----KVY  685

Query  823  HRTIAGTADDYAALRNNTAAAKLIEYTNHLTKQSVTARAALEPLVLMVAPLAPHLAEELW  882
            + T+ + +++   ++ NTA A+L+ + N   K+          +V ++AP+APHL+EELW
Sbjct  686  NETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELW  745

Query  883  RRL-GHDASLAHGPFPVADERYLVEDTVEYPVQVNGKVRGRVTvaadapadaveaaalad  941
            + L + + S++  P P  DE  LVE+ VE  VQ++GKV++++ VA D + + ++  ALA+
Sbjct  746  QALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALAN  805

Query  942  dkvvaFLDGKTPKKVIVVAGRLVNVVL  968
            +KV A + GK   KVI V+ +LVN+V+
Sbjct  806  EKVQAEIAGKDIIKVIAVPNKLVNIVI  832


 Score =  129 bits (474),  Expect = 7e-31, Method: Compositional matrix adjust.
 Identities = 74/150 (50%), Positives = 99/150 (66%), Gaps = 11/150 (7%)

Query  30   GEIERAWQQRWTQDGTFDVANPVGSLAPADGSAVPADKMFVQDMFPYPSGEGLHVGHPLG  89
              IE  WQ  W+++ TF             G+  +  K +  DMFPYPSG GLHVGHP G
Sbjct  7    TAIEPKWQAFWADNHTFKT-----------GTDASKPKFYALDMFPYPSGAGLHVGHPEG  55

Query  90   YIATDVYARYYRMTGRNVLHALGFDAFGLPAEQYAIQTGTHPRTRTEANIVNFRRQLGRL  149
            Y ATD+ +R+ R  G+NVLH++G DAFGLPAEQYA++TG +P   T  NI NF+RQ+  L
Sbjct  56   YTATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINAL  115

Query  150  GLGHDSRRSFSTTDVDFYKWTQWIFLQIYN  179
            G++ D  R  +TTD ++YKWTQWIF ++Y+
Sbjct  116  GFSYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1625) CARG_09545 in NC_022198


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  493 bits (1858),  Expect = 3e-140, Method: Compositional matrix adjust.
 Identities = 348/742 (47%), Positives = 494/742 (67%), Gaps = 68/742 (9%)

Query  213  LVYRSNSMVNWCPGLGTVLANEEVTADGKSERGNFPVFRKQLSQWMMRITAYSdrliddl  272
            L Y ++  VNW   LGT +ANEEV +DG SERG +PV RK + QWM++ITAY++RL++DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  273  dlldwpdKVKAMQRNWIGRSKGAEVDFDV--AGHTVTVFTTRPDTLFGASYVTLAPEHEL  330
            + +DWP+ +K MQRNWIG+S GA+V F V  ++   TVFTTRPDTLFGA+Y  LAPEH L
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  331  VDTLVTDTPYAADVDPKWTYNAASPMEaveayraaiaaKSDVERQE-NKDKTGVFLGVYA  389
            VD++ T     A  D    Y+  +++            KSD+ R +  K+KTGV  G YA
Sbjct  268  VDAITTSDQAEAVAD----YKRQASL------------KSDLARTDLAKEKTGVWTGSYA  311

Query  390  TNPVNGDKLPVFIADYVLTGYGTGAIMAVPAHDTRDYEFATEFNLPIIEVVAGGNIEQEA  449
             NPVNG  +PV IADYVL++YGTGAIMAVPAHD RD EFA +FNL II V+ GGN+E+ A
Sbjct  312  INPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEAA  371

Query  450  FVDAGTAVNSANDRGLDLNGMSLDEAKATTIEWLEAQGAGVGKIQYKLRDWLFARQRYWG  509
            F + G  +NS       L+G+    A A  +EWLEA+G G  ++ Y+LRDWLF+RQRYWG
Sbjct  372  FTEDGLHINSDF-----LDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWG  426

Query  510  EPFPIVYDEDGVAHALPDSMLPIELPEVDDYKPVSFDPEDADSSPQPPLAKATDWVNVEL  569
            EP+PI+  EDG + A+P+S LP+ LP   D +P         ++ ++PLA+ TDW++V  
Sbjct  427  EPIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTDWLEVTR  478

Query  570  DLGDGPKMYRRDTNVMPQWAGSSWYQLRYIDPENHDAFCDFANEQYWTGPQADRGAQDPG  629
            +  DG K  RR+TN MPQWAGSSWY LRYIDP+N + + D    + W             
Sbjct  479  E--DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLP-----------  524

Query  630  GVDLYVGGVEHAVLHLLYSRFWHKVLFDLGYVSSKEPYRRLFNQGYIQAFAYTDSRGVYV  689
             VD+YVGG EHAVLHLLY+RFWHKVL+DLG V++KEP+++LFNQG I + +Y DSRG  V
Sbjct  525  -VDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALV  583

Query  690  PAAEVEERDGQFFY--HGEPVTQEYGKMGKSLKNAVAPDEICDDYGADTLRVYEMAMGPL  747
            ++  VE RDG FF    GE + Q  +KM+KSLKN V PD++ ++YGADTLRVYEM MGPL
Sbjct  584  ATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPL  643

Query  748  DTSRPWATKDVVGAQRFLQRTWRLVVDEESGAIRLHDAALTDEDNKQLHR----TIAGVR  803
            D+S +W+  ++ G+++FL+R  RL+   E          +T+E++  L++    T+ +V 
Sbjct  644  DASIAWSEEGLEGSRKFLDRVYRLITTKE----------ITEENSGALDKVYNETVKAVT  693

Query  804  DDYDNLRMNTVVAKLIEYVNYVTKTYPDGAPRAAVEPLVLMLAPVAPHIAEELHQRLGGQ  863
            ++ D+++ NT +A+L+ +VN   K   D         +V ++AP APH++EEL Q L + 
Sbjct  694  EQVDQMKFNTAIAQLMVFVNAANKE--DKLFSDYAKGFVQLIAPFAPHLGEELWQALTAS  751

Query  864  S-TLAYEPFPTFEDKWLKDDSVELPVQVNGKVRGRMTvavdaskddllaaahaavaahvE  922
            + +++Y P P++++  L ++ VE+ VQ++GKV++++ VA D S+++L   A A    + E
Sbjct  752  GESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAE  811

Query  923  --GKTVVKEIVVPGRMVNLVVK  942
              GK ++K I VP ++VN+V+K
Sbjct  812  IAGKDIIKVIAVPNKLVNIVIK  833


 Score =  116 bits (423),  Expect = 8e-27, Method: Compositional matrix adjust.
 Identities = 77/151 (51%), Positives = 103/151 (69%), Gaps = 14/151 (9%)

Query  15   IESAWQNYWIDNGTFNAPNPVGNLAVENPANPGAADKPKLFVQDMFPFPSGAGLHVGHPL  74
            IE+ WQ +W DN TF++                 A KPK++  DMFP+PSGAGLHVGHP 
Sbjct  9    IEPKWQAFWADNHTFKTGT--------------DASKPKFYALDMFPYPSGAGLHVGHPE  54

Query  75   GYIATDVYARYNRMLGKNVLHTLGYDAFGLPAEQYAIQTGTHPRIKTQESIDNMErqlgr  134
            GY ATD+ +R++R  G NVLH +G DAFGLPAEQYA++TG +P   T E+I N  RQ+  
Sbjct  55   GYTATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINA  114

Query  135  lglghdrrrSVATTDVEFYKWTQWIFLQIFN  165
            LG++ D+ R V TTD ++YKWTQWIF ++++
Sbjct  115  LGFSYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1626) MAB_4923c in NC_010397


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  492 bits (1857),  Expect = 3e-140, Method: Compositional matrix adjust.
 Identities = 342/739 (47%), Positives = 499/739 (68%), Gaps = 65/739 (8%)

Query  224  LVYQSDSVVNWCPGLGTVLANEEVTADGRSERGNFPVFRKRLRQWMMRITAYSDRLIDDL  283
            L Y+++  VNW   LGT +ANEEV +DG SERG +PV RK +RQWM++ITAY++RL++DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  284  DVLDWPDKVKTMQRNWIGRSQGASVLFGAPGAG-DIEVFTTRPDTLFGATYMVLAPEHPL  342
            + +DWP+ +K MQRNWIG+S GA+V F   +++ D+ VFTTRPDTLFGATY VLAPEH+L
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  343  VDQLAADVWPQDTDPRWTGGQDSPRAAIEQYRRSIAAKSDLERQE-NKEKTGVFTGAYAT  401
            VD +++                    A+ +Y+R  + KSDL R +  KEKTGV TG+YA 
Sbjct  268  VDAITTS---------------DQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAI  312

Query  402  NPVSGKPVPVFIADYVLLGYGTGAIMAVPGHDQRDWDFANTFGLPVQEVISGGDVTKAAY  461
            NPV+GK +PV IADYVL +YGTGAIMAVP+HD+RDW+FA+ F L +  V+ GG+V  AA+
Sbjct  313  NPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEAAF  372

Query  462  TGDGVLVNSDYLDGLDIEAAKVEVTRRLVKDGRGESRIEYKLRDWLFARQRYWGEPFPIV  521
            T DG+ +NSD+LDGLD  +A   +  +L  +G G+  + Y+LRDWLF+RQRYWGEP+PI+
Sbjct  373  TEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPII  432

Query  522  YDEDGRPRALGENvlpvelpeveDYAPVsfdpddassepspplsKAADWVNVELDLGDGL  581
              EDG + A+ E+ LP+ LP   D  P        S+   +PL++ +DW++V  +  DG+
Sbjct  433  HWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTDWLEVTRE--DGV  482

Query  582  KHYTRDTNVMPQWAGSSWYELRYADPDNAEAFCDKENEAYWLGPRPAEHGPNDPGGVDLY  641
            K   R+TN MPQWAGSSWY LRY DP+N+E + D E    WL              VD+Y
Sbjct  483  KG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWL-------------PVDIY  528

Query  642  VGGMEHAVLHLLYSRFWHKVLYDLGHVSSREPYRRLLNQGYIQAHAYTDARGMYVPAAEV  701
            VGG EHAVLHLLY+RFWHKVLYDLG V+++EP+++L+NQG I + +Y D+RG  V++  V
Sbjct  529  VGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKV  588

Query  702  TEENGKFFY--QGAEVQQEFGKIGKSLKNSISPDDICDNYGADTLRVYEMSMGPLELSRP  759
               +G FF    G E++Q  +K++KSLKN ++PDD+ ++YGADTLRVYEM MGPL+ S +
Sbjct  589  EKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIA  648

Query  760  WATKDVVGAHRFLQRAWRVVVDEETGKIRVTTDDLTSEDTLRALHKTIAGVTEDYAALRN  819
            W+  ++ G+++FL+R  R++   E     +T ++  + D  +  + T+ +VTE+   ++ 
Sbjct  649  WSEEGLEGSRKFLDRVYRLITTKE-----ITEENSGALD--KVYNETVKAVTEQVDQMKF  701

Query  820  NTAAAKLIEYTN------HLTKDYPEGAPRaaveplvlmlaplaphlaeelW-SLLGRDD  872
            NTA A+L+ + N       L  DY+ G  +        ++AP+APHL+EELW +L + ++
Sbjct  702  NTAIAQLMVFVNAANKEDKLFSDYAKGFVQ--------LIAPFAPHLGEELWQALTASGE  753

Query  873  SLAHGPFPESDDRWLVADTVEYPIQVNGKVRGRITVAADAPKGDIEAAALTEEKVLEFLA  932
            S++  P P  D+  LV + VE  +Q++GKV++++ VA D ++ +++  AL++EKV   +A
Sbjct  754  SISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIA  813

Query  933  GATPKKVIVVPGRMVNLVV  951
            G    KVI VP ++VN+V+
Sbjct  814  GKDIIKVIAVPNKLVNIVI  832


 Score =  132 bits (486),  Expect = 8e-32, Method: Compositional matrix adjust.
 Identities = 78/148 (53%), Positives = 98/148 (67%), Gaps = 11/148 (7%)

Query  27   IERRWQQTWADRGTFHVPNPVGSLAPTDGTPIPADKMFVQDMFPYPSGDGLHVGHPLGYI  86
            IE +WQ  WAD  TF             GT  +  K +  DMFPYPSG GLHVGHP GY 
Sbjct  9    IEPKWQAFWADNHTFKT-----------GTDASKPKFYALDMFPYPSGAGLHVGHPEGYT  57

Query  87   ATDVYARFHRMRGANVLHALGFDAFGLPAEQYAVQTGTHPRVRTEANIVNYKRQLGRLGL  146
            ATD+ +RF R +G NVLH++G DAFGLPAEQYA++TG +P   T  NI N+KRQ+  LG+
Sbjct  58   ATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGF  117

Query  147  GHDSRRSFATTDVDFYKWTQWIFLQIYN  174
            + D  R   TTD ++YKWTQWIF ++Y+
Sbjct  118  SYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1627) leuS in NC_018177


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  492 bits (1855),  Expect = 4e-140, Method: Compositional matrix adjust.
 Identities = 358/883 (41%), Positives = 550/883 (63%), Gaps = 72/883 (8%)

Query  5    YQPREIEAAAQSHWEAQKSFEVSEQPGKDTFYCLSMFPYPSGK-LHMGHVRNYTIGDVIA  63
            Y+   IE+  Q+ W  + +F  + +++K  FY L MFPYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMLGKNVLQPMGWDAFGMPAENAAMKNQVAPAKWTYENIQYMKTQLKSLGLAVDWTR  123
            R++R  G NVL+PMGWDAFG+PAE+ AM     PA  T ENI   K Q+++LG++ DW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVTTCKPDYYRWEQWLFTRLYKKGVIYRKNGTVNWDPVDQTVLANEQVI-DGRGWRSGAL  182
            EV T  P+YY+W QW+FT+LY KG+ Y  +  VNW     T +ANE+V+ DG + R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  IEKREIPMYYFKITAYADELLESLDDLPGWPEQVKTMQRNWIGKSRGMEIGFPYDVASIG  242
            + ++ +    +KITAYA+ LLE L+++ +WPE +K MQRNWIGKS G ++ F       +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTF----KVKD  238

Query  243  SEGVMKVFTTRPDTLMGATYVAVAAEHPLATLAAQGNPELQAFIDECKRGGVAEADIA--  300
            ++    VFTTRPDTL GATY  +A+EH+L  + A   ++    + + KR +   +D+A  
Sbjct  239  TDKDFTVFTTRPDTLFGATYAVLAPEHAL--VDAITTSDQAEAVADYKRQASLKSDLART  296

Query  301  --TQEKKGLATALRVQHPLTGELLPVWVANYVLMGYGEGAVMAVPAHDERDFEFASKYGL  358
              ++EK G+ T+    +P+ G  +PVW+A+YVL +YG GA+MAVPAHDERD EFA ++ L
Sbjct  297  DLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNL  356

Query  359  PIKPVVRTSAGDETPAPWQDAYGEHGELINSgafdgldfdgafdaMEVALQKKGLGQART  418
             I PV+  +  +E+      A+ E+G  INS+ +DGLD  +A+  M   L+  G+G+   
Sbjct  357  DIIPVLEGGNVEEA------AFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENV  410

Query  419  QFRLRDWGISRQRYWGCPIPIIHCETCGDVPVPEDQlpvvlpedvvpdGAG---SPLAKM  475
             +RLRDW +SRQRYWG PIPIIH E     +VPE +LP+VLP       +G   SPLA++
Sbjct  411  TYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANV  470

Query  476  PEFYDCSCPSCGKPARRETDTMDTFVESSWYFARYASPNYEQGMVDPKAANHWLPVDQYI  535
             +  + +     K +RRET+TM     SSWY+ RY  P+  + + D    ++WLPVD Y+
Sbjct  471  TDWLEVTREDGVK-GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYV  529

Query  536  GGIEHAILHLLYARFFHKLMRDEGLVSSNEPFKNLLTQGMVVAETYYRTLPNGAKDWFNP  595
            GG EHA+LHLLYARF HK++ D G+V+++EPF++L+ QGM+++ +Y              
Sbjct  530  GGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY--------------  575

Query  596  ADVEVERDAKAKVIGAKL--KSDG--LPVEIG-----GTEKMSKSKNNGVDPQAMIDAYG  646
                  RD+++ ++++    K DG  + VE G     +  KMSKS +N V+P+ +++ YG
Sbjct  576  ------RDSRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYG  629

Query  647  ADTCRLFMMFASPPDMSCEWSDAGIEGANRFLRRVWRLAHAHVsaglpgaldlaalsdEQ  706
            ADT R++ MF +P D S  WS+ G+EG+ +FL RV RL  +                ++ 
Sbjct  630  ADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTK-----------EITEENS  678

Query  707  KAIRRATHLAIRQASIDVGQHHKFNTAIAQVMTLMNVLEKAPTASEQDRALLQEGLEAVA  766
             A+ +  + +++  + +V ++ KFNTAIAQ+M ++N       A++++  L+ +   +  
Sbjct  679  GALDKVYNETVKAVTEQV-DQMKFNTAIAQLMVFVN-------AANKEDKLFSDYAKGFV  730

Query  767  LLLAPITPHICHELWQQLGKAGSVID-AAWPKVDETALVQDNLTLVVQVNGKLRGQIEVP  825
             L+AP++PH+ +ELWQ L  +G  I   +WP  DE+ LV++++ +VVQ++GK+++++ V+
Sbjct  731  QLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVA  790

Query  826  asasreeveaaaranenvvrFTEGQTIRKVIVVPGKLVNIVAN  868
               SREE++  A ANE+V     G+ I KVI VP KLVNIV +
Sbjct  791  KDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

1628) leuS in NC_003888


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  492 bits (1855),  Expect = 5e-140, Method: Compositional matrix adjust.
 Identities = 361/744 (49%), Positives = 496/744 (67%), Gaps = 66/744 (8%)

Query  227  LAYASDAPVNWCPGLGTVLANEEVTADGRSERGNFPVFKSKLRQWNMRITAYAdrllddl  286
            LAY ++ PVNW   LGT +ANEEV +DG SERG +PV +  +RQW ++ITAYA+RLL+DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  287  dqldWPEAIKLQQRNWIGRSEGARVDFPV-DGER-ITVFTTRPDTLFGATYMVLAPEHPL  344
            +++DWPE+IK  QRNWIG+S GA V F V D ++ +TVFTTRPDTLFGATY VLAPEH+L
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  345  VEKFTPAVWPEGTRDAWTGGHATPTEAVAAYRAQAASKSDVERQAEAKDKTGVFIGAYAT  404
            V+ +T +                 +EAVA Y+ QA+ KSD+ R   AK+KTGV  G+YA 
Sbjct  268  VDAITTS---------------DQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAI  312

Query  405  NPVNGEQVPVFVADYVLMGYGTGAIMAVPAHDSRDFEFARAFELPVRCVVEPTDGRGTDT  464
            NPVNG ++PV +ADYVL +YGTGAIMAVPAHD RD EFA+ F+L +  V+E  +      
Sbjct  313  NPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVE----  368

Query  465  STWDEAFASYDAKIVNSSGTDVSLDGLGVVEAKERVTEWLERAGAGAGTVNFRLRDWLFS  524
               + AF+  D+  +NS      LDGL+   A  ++ EWLE  G G   V +RLRDWLFS
Sbjct  369  ---EAAFTE-DGLHINSD----FLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  525  RQRYWGEPFPIVYDEDGIAHPLPDSMLPLELPEVEDYSPRTFDPDDADTKPETPLSRNED  584
            RQRYWGEP+PI+  EDG + ++P+S LPL LP   D  P            E+PL+   D
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTD  472

Query  585  WVHVTLDLGDGRGPRKYRRETNTMPNWAGSCWYELRYLDPHNGERLVDPEIEQYWMGPRE  644
            W++VT + ++ +G    RRETNTMP+WAGS WY LRY+DPHN E+L D E+ + W+    
Sbjct  473  WLEVTRE-DGVKG----RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLP---  524

Query  645  GLPHGGVDLYVGGAEHAVLHLLYARFWSKVLFDLGHVSSAEPFHKLFNQGMIQAYVYRDS  704
                  VD+YVGGAEHAVLHLLYARFW KVL+DLG V++ EPF+KLFNQGMI +  YRDS
Sbjct  525  ------VDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDS  578

Query  705  RGIAVPAAEVEERDGAYYY--QGEKVSRLLGKMGKSLKNAVTPDEICAEYGADTLRLYEM  762
            RG  V++  VE RDG+++    GE + +  +KM+KSLKN V PD++  +YGADTLR+YEM
Sbjct  579  RGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEM  638

Query  763  AMGPLDVSRPWDTRAVVGQFRLLQRLWRNVVDEDTGELSVADVAESDIDAGTL-RALHKA  821
             MGPLD S +W   ++ G  ++L+R+ R +   +           ++ ++G+L +  + +
Sbjct  639  FMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEI----------TEENSGALDKVYNET  688

Query  822  VDGVRQDLEGMRFNTAIAKVTELNNHLTKAGGPVPRSvaerlvllvaplaphvaeELWRK  881
            V +V ++++ M+FNTAIA++  + N   K  + +    A  +V L+AP+APH++EELW+ 
Sbjct  689  VKAVTEQVDQMKFNTAIAQLMVFVNAANKE-DKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  882  L-GHESSVVHEDFPVADPAYVVDETVTCVVQIKGKVKARLEVAPSISEDDLEKAALADEK  940
            L +   S+     P  D + +V++ V  VVQIKGKVKA+L VA  +S ++L+  ALA+EK
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  941  VVAALGGAGIRKVIVRAPKLVNIV  964
            V A ++G +I KVI  + KLVNIV
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIV  831


 Score =  124 bits (454),  Expect = 3e-29, Method: Compositional matrix adjust.
 Identities = 75/150 (50%), Positives = 103/150 (69%), Gaps = 10/150 (6%)

Query  27   AEIEARWQDFWDAEGTYAAPNPKGDLAGDPELVAKPKKFIMDMFPYPSGAGLHVGHPLGY  86
            + IE++WQ FW  + T+ +              +KPK + +DMFPYPSGAGLHVGHP GY
Sbjct  7    TAIEPKWQAFWADNHTFKTGTD----------ASKPKFYALDMFPYPSGAGLHVGHPEGY  56

Query  87   IATDVFARFQRMTGHNVLHTLGFDAFGLPAEQYAVQTGTHPRVSTEANMKNMQSQlrrlg  146
             ATD+++RF+R  GHNVLH +G DAFGLPAEQYA++TG +P   T  N+ N + Q+  LG
Sbjct  57   TATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALG  116

Query  147  lghdrrrSFATIDPEYYKWTQWIFLQIFNS  176
            ++ D+ R   T DP+YYKWTQWIF ++++ 
Sbjct  117  FSYDWDREVNTTDPNYYKWTQWIFTKLYEK  146

1629) leuS in NC_021915


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  491 bits (1851),  Expect = 1e-139, Method: Compositional matrix adjust.
 Identities = 345/739 (47%), Positives = 509/739 (69%), Gaps = 60/739 (8%)

Query  217  LVYRSNSMVNWCPGLGTVLANEEVTADGRSERGNFPVFRKRLSQWMMRITAYSdrllddl  276
            L Y ++  VNW   LGT +ANEEV +DG SERG +PV RK + QWM++ITAY++RLL+DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  277  elldWPEKVKSMQRNWIGRSRGAEVDFTAGETT--IRVFTTRADTLFGATYMAIAPeael  334
            E +DWPE +K MQRNWIG+S GA+V F   +T   + VFTTR+DTLFGATY  +AP    
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAP----  263

Query  335  aaelVSDEPYAADVDQRWTYGAASPQEALAAYRRDIAAKSDVERQE-NKDKTGVFLGTYA  393
                  +++    +       ++   EA+A Y+R+ + KSD+ R +  K+KTGV  G+YA
Sbjct  264  ------EHALVDAI------TTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYA  311

Query  394  TNPVNGAQIPIFAADYVLAGYGTGALMAVPAHDERDYEFATAFGVEILPVLDG-DVSEQA  452
             NPVNG ++P+  ADYVLA+YGTGA+MAVPAHDERD EFA  F ++I+PVL+G +V E A
Sbjct  312  INPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEAA  371

Query  453  FLGDAAHINSANDSGLGLNGLGKDEAIAATIAWLVDNERGAEKIQYKLRDWLFARQRYWG  512
            F  D+ HINS       L+GL+K  AIA  + WL  +  G E++ Y+LRDWLF+RQRYWG
Sbjct  372  FTEDGLHINSDF-----LDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWG  426

Query  513  EPFPIVYDDNGVAHAlpeemlpvelpevDDYAPAAHDPNDADSEPQPPLAKVTDWVNVEL  572
            EP+PI+  ++G + A+PE  LP+ LP   D  P++ +        ++PLA+VTDW++V  
Sbjct  427  EPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTG--------ESPLANVTDWLEVTR  478

Query  573  DLGDGPRTYTRDTNVMPQWAGSSWYQLRYVDPTNDEKFVDLDNERYWTGPQPEKHGADDP  632
            + G   R   R+TN MPQWAGSSWY LRY+DP N EK+ D +  + W             
Sbjct  479  EDGVKGR---RETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLP-----------  524

Query  633  GGVDLYVGGVEHAVLHLLYSRFWHKVLYDLGHVSSKEPYRRLYNQGYIQAYAYTDARGVY  692
              VD+YVGG EHAVLHLLY+RFWHKVLYDLG V++KEP+++L+NQG I + +Y D+RG  
Sbjct  525  --VDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGAL  582

Query  693  VPAEEVEERDGKFFHGD--EEVTQEYGKMGKSLKNAVAPDDIVRDFGADTLRVYEMSMGP  750
            V+++ VE RDG FFH +  EE+ Q  +KM+KSLKN V PDD+V ++GADTLRVYEM MGP
Sbjct  583  VATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGP  642

Query  751  LDTSRPWATKDVVGAHRFLQRLWRLVVDEDTGEVYTVDAELTDEDNKQLHRTIAGVRDDY  810
            LD+S +W+  ++ G+++FL+R+ RL+   +  E      E ++  +K  + T+ +V ++ 
Sbjct  643  LDASIAWSEEGLEGSRKFLDRVYRLITTKEITE------ENSGALDKVYNETVKAVTEQV  696

Query  811  ANLRDNTVVAKLIEYVNYLTKTYPNDVPLAAVEPLVVMVSPLAPHIAEELWSKL-GHDET  869
             +++ NT +A+L+ +VN   K   + +       +V +++P+APH++EELW  L + +E+
Sbjct  697  DQMKFNTAIAQLMVFVNAANKE--DKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGES  754

Query  870  ITFTAFPTFDEAWLVDDEIELPVQVNGKVKARIMvpadagqddvvavaladekvaalvEG  929
            I++ + P++DE+ LV++++E+ VQ++GKVKA+++V+ D +++++  VALA+EKV A + G
Sbjct  755  ISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAG  814

Query  930  KNLVKQIVVPGRMVNLVVK  948
            K+++K I VP ++VN+V+K
Sbjct  815  KDIIKVIAVPNKLVNIVIK  833


 Score =  142 bits (522),  Expect = 1e-34, Method: Compositional matrix adjust.
 Identities = 77/151 (51%), Positives = 106/151 (71%), Gaps = 11/151 (7%)

Query  18   NEIETTWQRYWNDKDTFNAPNPVGDLAPADGQQLPEDKLFVQDMFPYPSGAGLHVGHPLG  77
              IE  WQ +W D++TF++           G + +  K++  DMFPYPSGAGLHVGHP G
Sbjct  7    TAIEPKWQAFWADNHTFKT-----------GTDASKPKFYALDMFPYPSGAGLHVGHPEG  55

Query  78   YIATDVFARYHRMLGKNVLHTLGYDAFGLPAEQYAIQTGTHPRTTTMNNIENMRRQLGSL  137
            Y ATD+++R+ R  G NVLH +G DAFGLPAEQYA++TG +P   T +NI N +RQ+ +L
Sbjct  56   YTATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINAL  115

Query  138  GLGHDRRRSVATTDPEFYKWTQWIFLQIYNS  168
            G++ D+ R V TTDP++YKWTQWIF ++Y+ 
Sbjct  116  GFSYDWDREVNTTDPNYYKWTQWIFTKLYEK  146

1630) leuS in NC_018868


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  491 bits (1851),  Expect = 9e-140, Method: Compositional matrix adjust.
 Identities = 344/856 (41%), Positives = 523/856 (62%), Gaps = 71/856 (8%)

Query  11   YHPDQIEAATQTFWETEKSFVVTEDSSREKFYCLSMFPYPSGK-LHMGHVRNYTISDVIA  69
            Y+   IE+  Q+FW  + +F    D+S+ KFY L MFPYPSG  LH+GH   YT +D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  70   RYQRMQGKNVLHPMGWDAFGLPAENAAIKHNTAPAAWTYSNTDYMRGQLKRLGFGFDWSR  129
            R++R QG NVLHPMGWDAFGLPAE+ A+     PA  T  N    + Q++ LGF++DW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  130  EVTTCKPDYYKWEQWFFTRLIEKGLAYKKVSSVNWCPNDMTVLANEQVI-DGCCWRCDSK  188
            EV T  P+YYKW QW+FT+L EKGLAY    +VNW  +  T +ANE+V+ DG   R +  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  189  VERKEIPQWFIKITDYAEqllndldqldEWPEQVRTMQRNWIGKSQGVEMTFELEAPVGE  248
            V RK + QW +KIT YAE  L +  +  +WPE ++ MQRNWIGKS G ++TF +      
Sbjct  184  VVRKPMRQWMLKITAYAE-RLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDT---  239

Query  249  HTAFDVYTTRPDTLMGVTYVSLAAEHPISKKlaennaalaafiaeCKIQSVSEADMA---  305
            +  F V+TTRPDTL G TY  LA+EH++    A   +  A  +A+ K Q+   +D+A   
Sbjct  240  DKDFTVFTTRPDTLFGATYAVLAPEHALVD--AITTSDQAEAVADYKRQASLKSDLARTD  297

Query  306  -TMDKKGFDTGIKALHPLTGKPVAVWVANYVLMDYGSGAVMAVPAHDQRDFEFAQKYGLA  364
             + +K G  TG  A++P+ GK ++VW+A+YVL  YG+GA+MAVPAHD+RD EFA+++ L 
Sbjct  298  LAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLD  357

Query  365  IEQVIDGEGDLTKAAITEKGKLINSGEFDGLEFQAAFDAIAAKLQQENKGRITTNFRLRD  424
            I  V++G G++  AA+TE G  INS+ +DGL+  +A+  +   L+ E  G     +RLRD
Sbjct  358  IIPVLEG-GNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  425  WGVSRQRYWGAPIPVLYLNGGKEIPVPASRLPVLLP--EEVVMDGV-HSPIKKDEQWRK-  480
            W  SRQRYWG PIP++  ++G   +VP S LP++LP   ++   G  +SP+ +  +W   
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  481  TEFDGQAAEHETDTFDTFMESSWYYARYTCANFDGGMIDKAAADYWLPVDQYVGGIEHAI  540
            T  DG  + +ET+T      SSWYY RY  ++    + D      WLPVD YVGG EHA+
Sbjct  477  TREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAV  536

Query  541  LHLLYARFFHKLMRDEGLVSGDEPFKRLLCQGMVL-------------------KDGT--  579
            LHLLYARF HK++ D G+V+  EPF++L+ QGM+L                   +DG+  
Sbjct  537  LHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFF  596

Query  580  -------------KMSKSKGNTVDPQELIDQYGADTVRLFTMFAAPPEQSLEWNDAGVEG  626
                         KMSKS  N V+P+++++QYGADT+R++ MF +P + S+ W++ G+EG
Sbjct  597  HVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEG  656

Query  627  AHRFLRKLWKAVHAHQQAGTAPELKVDSLTGPQKDLRRKTHETIAKVSDDYGRRQTFNTA  686
            +++FL ++ + + + + +   +             L +  +ET+  V+++ ++ + FNTA
Sbjct  657  SRKFLDRVYRLITTKEITEENSG-----------ALDKVYNETVKAVTEQVDQMK-FNTA  704

Query  687  IAAVMELLNDVTRFERKDDQDlavereallaavqllaPIVPHICHTLWAGL-GRGDNLLD  745
            IA +M ++N   +       +  +  +   + VQL+AP+ PH+ + LW +L + G+++  
Sbjct  705  IAQLMVFVNAANK-------EDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISY  757

Query  746  AGWPQLDEAALVKSELELVVQINGKVRAKITVAADADNDTIIALAKSNDNVQKFLDGVEI  805
              WP  DE+ LV +++E+VVQI+GKV+AK+ VA D   + +  +A +N++VQ  + G +I
Sbjct  758  VPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDI  817

Query  806  KMCKVVPGKLVTFAVK  821
                 VP KLV + +K
Sbjct  818  IKVIAVPNKLVNIVIK  833

1631) leuS in NC_020504


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  490 bits (1849),  Expect = 1e-139, Method: Compositional matrix adjust.
 Identities = 351/739 (48%), Positives = 492/739 (67%), Gaps = 59/739 (7%)

Query  222  LAYASEAPVNWCPGLGTVLANEEVTAEGRSERGNFPVFKAKLRQWNMRITAYadrllddl  281
            LAY +E PVNW   LGT +ANEEV ++G SERG +PV +  +RQW ++ITAYA+RLL+DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  282  daldWPEAIKLQQRNWIGRSEGARVDFPIDG--EHITVFTTRPDTLFGASYMVLAPEHPL  339
            + +DWPE+IK  QRNWIG+S GA V F + +   ++TVFTTRPDTLFGA+Y VLAPEH+L
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  340  VEKFTPAAWPEGTHDVWTGGHATPaeavaayraqaaSKSDVERQAEAKDKTGVFIGAYAT  399
            V+ +T +  +E+  D               Y+ QA+ KSD+ R   AK+KTGV  G+YA 
Sbjct  268  VDAITTSDQAEAVAD---------------YKRQASLKSDLARTDLAKEKTGVWTGSYAI  312

Query  400  NPVNGKQVPVFIADYVLMGYGTGAIMAVPCGDQRDFEFARAFELPIVCIVEPTDGRGTDT  459
            NPVNGK++PV IADYVL +YGTGAIMAVP  D+RD EFA+ F+L I+ ++E  +      
Sbjct  313  NPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEE---  369

Query  460  STWEDAFSSYDAKIINSTGEGVSLDGLGVAEAKARITEWLERTGTGEGTVNFRLRDWLFS  519
                   +++    ++  ++   LDGL+ A A A++ EWLE  G G+  V +RLRDWLFS
Sbjct  370  -------AAFTEDGLHINSD--FLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  520  RQRYWGEPFPIVYDEDGTAHPLPDSMLPLELPEVEDYSPRTFDPDDANTSPETPLSRNED  579
            RQRYWGEP+PI+  EDGT+ ++P+S LPL LP   D  P        + + E+PL+   D
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTD  472

Query  580  WVNVTLDLGDGPKKYRRETNTMPNWAGSCWYELRYLDPHNSARLVDPDIEQYWMGPREGM  639
            W++VT +  DG K  RRETNTMP+WAGS WY LRY+DPHN+ +L D ++ + W+      
Sbjct  473  WLEVTRE--DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLP-----  524

Query  640  PHGGVDLYVGGAEHAVLHLLYARFWSKVLFDLGHVSSAEPFHKLFNQGMIQAYVYRDSRG  699
                VD+YVGGAEHAVLHLLYARFW KVL+DLG V++ EPF+KLFNQGMI +  YRDSRG
Sbjct  525  ----VDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRG  580

Query  700  IAVPAAEVEEREGAYYY--QGEKVSRLLGKMGKSLKNAVTPDEICAEYGADTLRLYEMAM  757
              V++  VE R+G+++    GE + +  +KM+KSLKN V PD++  +YGADTLR+YEM M
Sbjct  581  ALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFM  640

Query  758  GPLDVSRPWDTRAVVGQFRLLQRLWRNVVDEASGAVTVVDAEADEDTLRALHKAIDGVRG  817
            GPLD S +W   ++ G  ++L+R+ R +          +  E      +  + ++ +V  
Sbjct  641  GPLDASIAWSEEGLEGSRKFLDRVYRLITTKE------ITEENSGALDKVYNETVKAVTE  694

Query  818  DLEGMRFNTAIAKVTELNNHLTKAGGAVPRSvaealvllvaplapHIAEELWRKL-GHED  876
            +++ M+FNTAIA++  + N   K +   +   A ++V L+AP+APH++EELW+ L +  +
Sbjct  695  QVDQMKFNTAIAQLMVFVNAANKEDKLFS-DYAKGFVQLIAPFAPHLGEELWQALTASGE  753

Query  877  SVVHQDFPVADPAYVVDETVTCVVQIKGKVKARLEVSPSISEEELEKVALGDDKVVAALD  936
            S+     P  D + +V++ V  VVQIKGKVKA+L V+  +S EEL+ VAL+++KV A + 
Sbjct  754  SISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIA  813

Query  937  GAGIRKVIVRAPKLVNIVT  955
            G +I KVI  + KLVNIV 
Sbjct  814  GKDIIKVIAVPNKLVNIVI  832


 Score =  139 bits (510),  Expect = 1e-33, Method: Compositional matrix adjust.
 Identities = 77/148 (53%), Positives = 101/148 (69%), Gaps = 10/148 (6%)

Query  26   IEARWQDFWDADGTYAAPNPSGDLAGDPALVAKPKKFIMDMFPYPSGAGLHVGHPLGYIA  85
            IE++WQ FW  + T+ +   +          +KPK + +DMFPYPSGAGLHVGHP GY A
Sbjct  9    IEPKWQAFWADNHTFKTGTDA----------SKPKFYALDMFPYPSGAGLHVGHPEGYTA  58

Query  86   TDVAARFQRMTGHNVLHTLGFDAFGLPAEQYAVQTGTHPRVSTEANIENMKAQLRRLGLG  145
            TD+ +RF+R  GHNVLH +G DAFGLPAEQYA++TG +P   T  NI N K Q+  LG++
Sbjct  59   TDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFS  118

Query  146  HDKRRSFATIDPDYYKWTQWIFLQIFNS  173
             D  R   T DP+YYKWTQWIF ++++ 
Sbjct  119  YDWDREVNTTDPNYYKWTQWIFTKLYEK  146

1632) leuS in NC_013131


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  490 bits (1849),  Expect = 1e-139, Method: Compositional matrix adjust.
 Identities = 341/744 (46%), Positives = 489/744 (66%), Gaps = 63/744 (8%)

Query  216  LAYIAEAPVNWCPGLGTVLSNEEVTADGRSERGNFPVFKRNLRQWMMRITKYGdrlladl  275
            LAY AE PVNW   LGT ++NEEV +DG SERG +PV ++ +RQWM++IT Y++RLL DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  276  drldWPEPIKLQQRNWIGRSEGARVHFGVTAVDGSQKTIEIFTTRPDTLFGATYMVLAPE  335
            + +DWPE+IK  QRNWIG+S GA V F    V +++K + +FTTRPDTLFGATY VLAPE
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTF---KVKDTDKDFTVFTTRPDTLFGATYAVLAPE  264

Query  336  HELVDSFVAKEWPAGTREKWTGGHATPaeavaayraqaaaKSEVERQTEGRQKTGVFTGT  395
            H LVD++ + +                AEAVA Y+ QA+ KS++ R   +++KTGV TG+
Sbjct  265  HALVDAITTSD---------------QAEAVADYKRQASLKSDLARTDLAKEKTGVWTGS  309

Query  396  FAVNPVDGQGVPVFIADYVLMGYGTGAIMAVPAHDQRDFEFAQAFDLPMRIvvappadwp  455
            +A+NPV+G+ +PV IADYVL +YGTGAIMAVPAHD+RD EFA+ F+L +           
Sbjct  310  YAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDI-------IPVL  362

Query  456  vdvadwTESYDSKTAQITDSANDEITLEGLPVPAAIRAITEWLQGKGIGEGTVTYRLRDW  515
             +      ++     +I         L+GL  ++AI  + EWL++ G+G+  VTYRLRDW
Sbjct  363  EGGNVEEAAFTEDGLHINSD-----FLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDW  417

Query  516  LFSRQRYWGEPFPIVYPVNGPEAGVAKAlpesmlplelpeveDFSPKTFEAGDVTSAPEP  575
            LFSRQRYWGEP+PI+   +G  ++V+ +    +LP+      D+ P        +++ E+
Sbjct  418  LFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTK----DIRP--------SGTGES  465

Query  576  PLARAADWVNVTLDLGDGPRQYHRETNTMPQWAGSCWYYLRYLSPGDDTRFVDAAAEKYW  635
            PLA  +DW++VT + G   R   RETNTMPQWAGS WYYLRY+ P +  ++ D    K W
Sbjct  466  PLANVTDWLEVTREDGVKGR---RETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQW  522

Query  636  MGPQDAEDTGGVDLYVGGAEHAVLHLLYARFWHKVLFDLGHVTSAEPFRKLYNQGMIQGA  695
            +          VD+YVGGAEHAVLHLLYARFWHKVL+DLG V + EPF+KL+NQGMI G+
Sbjct  523  LP---------VDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGT  573

Query  696  SYTDARGVYVEASRVEERDGAFTY--EGEQVTQHFGKIGKSLKNVISPDDMIDEYSADTL  753
            SY D+RG  V + +VE RDG+F     GE++ Q  +K++KSLKNV++PDD++++Y+ADTL
Sbjct  574  SYRDSRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTL  633

Query  754  RIYEMSMGPLDMSKPWDTRASIGSFRFLQRLWRNVIDEETGEVTVVDAEPDEATLRALHK  813
            R+YEM MGPLD S +W   +  GS +FL+R+ R +   E  E      E   A  +  + 
Sbjct  634  RVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITE------ENSGALDKVYNE  687

Query  814  TIDGARADMEGMRFNTAISKLIELNNHLTRLPAVPRSAAEALVVLTAPFAPHIAEELWSR  873
            T+ +   +++ M+FNTAI++L+ + N   +   +    A ++V L APFAPH++EELW  
Sbjct  688  TVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  874  LGHDG-SVARAAYPVANPAYLVDETVTCVVQVAGKVKDRLEVPPGIAQDALRELALASEG  932
            L   G S++  + P  + + LV++ V  VVQ+ GKVK +L V+ +++++ L+E+ALA+E 
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  933  VQRALEGRGVRAVIVRAPKLVNVV  956
            VQ  + G+++  VI  + KLVN+V
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIV  831


 Score =  151 bits (556),  Expect = 2e-37, Method: Compositional matrix adjust.
 Identities = 81/143 (57%), Positives = 107/143 (75%), Gaps = 3/143 (2%)

Query  25   ADIEPKWQEYWAENHTFEVPDQPADTAEPKAYILDMFPYPSGAGLHVGHPLGYIATDVLG  84
            + IEPKWQ +WA+NHTF      +D++ PK Y LDMFPYPSGAGLHVGHP GY ATD+L+
Sbjct  7    TAIEPKWQAFWADNHTFKTG---TDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  85   RYKMMTGHKVLHTIGFDAFGLAAEQYAVEHGIHPRVSTERNIARYKEQIHRIGFGHDTRR  144
            R+K   GH+VLH +G DAFGL+AEQYA++ G +P   T  NIA +K QI+ +GF+ D  R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  145  GVSTIDVSFYKWTQWIFLQIFNS  167
             V+T D ++YKWTQWIF ++++ 
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEK  146

1633) leuS in NC_013929


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  490 bits (1846),  Expect = 2e-139, Method: Compositional matrix adjust.
 Identities = 363/739 (50%), Positives = 492/739 (67%), Gaps = 59/739 (7%)

Query  227  LAYASDAPVNWCPGLGTVLANEEVTADGRSERGNFPVFKAKLRQWNMRITAYADRLLDDL  286
            LAY ++ PVNW   LGT +ANEEV +DG SERG +PV +  +RQW ++ITAYA+RLL+DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  287  NELDWPEAIKLQQRNWIGRSEGARVDFPVD--GEHITVFTTRPDTLFGATYMVLAPEHPL  344
            +E+DWPE+IK  QRNWIG+S GA V F V   + ++TVFTTRPDTLFGATY VLAPEH+L
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  345  VDKFTPDAWPEGTHDVWTGGHATPaeavaayraqaaSKSDVERQAEAKDKTGVFTGSYAT  404
            VD +T    +E+  D               Y+ QA+ KSD+ R   AK+KTGV TGSYA 
Sbjct  268  VDAITTSDQAEAVAD---------------YKRQASLKSDLARTDLAKEKTGVWTGSYAI  312

Query  405  NPVNGERVPVFIADYVLMGYGTGAIMAVPAGDQRDFEFARAFELPVVCIVEPTDGRGTDT  464
            NPVNG  +PV IADYVL +YGTGAIMAVPA D+RD EFA+ F+L ++ ++E  +      
Sbjct  313  NPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEE---  369

Query  465  STWEDAFASYDAKIINSTGEGVSLDGLGVVEAKARITEWLERTGIGQGTVNFRLRDWLFS  524
                   A++    ++  ++   LDGL+   A A++ EWLE  G+G+  V +RLRDWLFS
Sbjct  370  -------AAFTEDGLHINSD--FLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  525  RQRYWGEPFPIVYDEDGVAHplpesmlplelpeveDYSPRTFEPDDADTRPETPLSRNED  584
            RQRYWGEP+PI+  EDG + ++PES LPL LP   D  P            E+PL+   D
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTD  472

Query  585  WVNVTLDLGDGPKRYRRETNTMPNWAGSCWYELRYLDPHNSEKLVDPEIERYWMGPREGQ  644
            W++VT +  DG K  RRETNTMP+WAGS WY LRY+DPHN+EKL D E+ + W+      
Sbjct  473  WLEVTRE--DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWL------  523

Query  645  PHGGVDLYVGGAEHAVLHLLYARFWSKVLFDLGHVSSAEPFHKLFNQGMIQAFVYRDSRG  704
                VD+YVGGAEHAVLHLLYARFW KVL+DLG V++ EPF+KLFNQGMI +  YRDSRG
Sbjct  524  ---PVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRG  580

Query  705  FAVPAAEVEERDGAYFH--QGEKVSRLLGKMGKSLKNAVTPESICEEYGADTLRLYEMAM  762
              V++  VE RDG++FH   GE + +  +KM+KSLKN V P+ + E+YGADTLR+YEM M
Sbjct  581  ALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFM  640

Query  763  GPLDVSRPWDTRAVVGQYRLLQRLWRNvvdettgevtvvdtepgedtLRALHKAIDGVRQ  822
            GPLD S +W   ++ G  ++L+R+ R +      E      +      +  + ++ +V +
Sbjct  641  GPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALD------KVYNETVKAVTE  694

Query  823  DLEGMRFNTAIAKVTELNNHLTKAGGPVSRpvaealvllvaplapHIAEELWRRL-GHTD  881
            +++ M+FNTAIA++  + N   K  + +    A ++V L+AP+APH++EELW+ L +  +
Sbjct  695  QVDQMKFNTAIAQLMVFVNAANKE-DKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGE  753

Query  882  SVVHQDFPVADPAYVVDEAVTCVVQIKGKVKARLEVSPAISEDELEKVALGDEKVVAALA  941
            S+     P  D + +V++ V  VVQIKGKVKA+L V+  +S +EL+ VAL++EKV A +A
Sbjct  754  SISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIA  813

Query  942  GAPIRKVIVRAPKLVNIVT  960
            G  I KVI  + KLVNIV 
Sbjct  814  GKDIIKVIAVPNKLVNIVI  832


 Score =  133 bits (487),  Expect = 6e-32, Method: Compositional matrix adjust.
 Identities = 75/150 (50%), Positives = 99/150 (66%), Gaps = 10/150 (6%)

Query  29   ADIEARWQDFWDAEGTYAAPNPTGDLAGDAELAAKPKKFIMDMFPYPSGAGLHVGHPLGY  88
            + IE++WQ FW  + T+ +             A+KPK + +DMFPYPSGAGLHVGHP GY
Sbjct  7    TAIEPKWQAFWADNHTFKTGTD----------ASKPKFYALDMFPYPSGAGLHVGHPEGY  56

Query  89   IATDVSARFQRMTGHNVLHTLGFDAFGLPAEQHAVATGEHPRVTTEAAINNMKSQLRRLG  148
             ATD+ +RF+R  GHNVLH +G DAFGLPAEQ A+ TG++P   T   I N K Q+  LG
Sbjct  57   TATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALG  116

Query  149  LGHDKRRSFATIDQDYYKWTQWIFLQIFNS  178
            ++ D  R   T D +YYKWTQWIF ++++ 
Sbjct  117  FSYDWDREVNTTDPNYYKWTQWIFTKLYEK  146

1634) leuS in NC_008340


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  490 bits (1848),  Expect = 2e-139, Method: Compositional matrix adjust.
 Identities = 357/871 (41%), Positives = 538/871 (62%), Gaps = 52/871 (5%)

Query  5    YQPEQIEAQAQRYWDEQQSFAAREEREGEKFYCLSMFPYPSGR-LHMGHVRNYTIGDVIS  63
            Y+   IE++ Q +W ++++F +  +    KFY L MFPYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMQGRNVLQPMGWDAFGLPAENAAMKHGVPPARWTRENIETMRGQLQRLGFAYDWDR  123
            R++R QG+NVL+PMGWDAFGLPAE+ AM  G  PA  T ENI   + Q++ LGF+YDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EFATCDPEYYRWEQWLFTRLYKKGLVYKKTATVNWDPVDQTVLANEQVV-DGRGWRSGAV  182
            E  T DP+YY+W QW+FT+LY KGL Y     VNW     T +ANE+V+ DG + R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERRDIPQWFLRITDYadellealdelPGWPEQVRAMQRNWIGRSEGVELDFAVAGHSDT  242
            V R+ + QW L+IT YA+ LLE L+E+ +WPE ++ MQRNWIG+S G ++ F V +    
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  LRVYTTRPDTLYGVTYVGlapehplaaeaaeGNPEMQRFIEDCRKGGVAEADIA----TM  298
            + V+TTRPDTL+G TY  LAPEH+L    + ++      + D ++ +   +D+A    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEA--VADYKRQASLKSDLARTDLAK  300

Query  299  EKRGMDTGLKAVHPLTGEQVPIWVANFVLMEYGHGAVMAVPAHDQRDWEFASKYGLDIRP  358
            EK G+ TG  A++P+ G ++P+W+A++VL  YG GA+MAVPAHD+RDWEFA ++ LDI P
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  359  VVHPSAEERADVSEGAFTDDGVLADSGEFSGLPSAEARQAIgekleglgkgeRTVNYRLR  418
            V+     E ++V E+AFT+DG+  +S+ + GL  A A   + E LE+ G G+  V YRLR
Sbjct  361  VL-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  419  DWGISRQRYWGAPIPMIQ---CPACGdvpvpdedlpvvlpedvdvTGGGSPLKDLPAFYQ  475
            DW +SRQRYWG PIP+I+     + +        +  V  +      G SPL ++    +
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  476  TTCPQCGGEARRETDTFDTFMESSWYYARFACADQKGAMLDER-ADQWLPVDQYIGGIEH  534
             T  + G  +RRET+T      SSWYY R+  +++   + DE    QWLPVD Y+GG EH
Sbjct  476  VTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEH  534

Query  535  AILHLLYARFFHKLMRDEGLLQSDEPFRNLLTQGMVIAETYYRERGDGGKDWYNPAEVTV  594
            A+LHLLYARF HK++ D G++ + EPF++L+ QGM+++ +Y   RG             V
Sbjct  535  AVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGA-----------LV  583

Query  595  QRDERGRPVSAVLEDDGEPVVMGAIEKMSKSKNNGVDPQALIDRYGADTVRLYTMFAAPP  654
              D   +  ++ ++ +    +  A  KMSKS +N V+P+ ++++YGADT+R+Y MF +P 
Sbjct  584  ATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPL  643

Query  655  DQSLEWSDSAVEGAYRFLRRYYGLVRDHVAAGPVPALDVASLDDAARDLRRKVHETIAKA  714
            D S+ WS+ ++EG+ +FL R Y L+     +           ++ +  L +  +ET+   
Sbjct  644  DASIAWSEEGLEGSRKFLDRVYRLITTKEIT-----------EENSGALDKVYNETVKAV  692

Query  715  SDDVGRRYTFNTAIAAVMELCNALGKAAANEPSGAARAVLQEGLEAATLILAPIAPHVTH  774
            +++V++   FNTAIA +M + NA  K   +  S+ A++ +Q        ++AP+APH+ +
Sbjct  693  TEQVDQM-KFNTAIAQLMVFVNAANK-EDKLFSDYAKGFVQ--------LIAPFAPHLGE  742

Query  775  VCWQALGHDEAVID-ARWPAVDESALTRDTIELVVQVNGKLRSRLQLPadadkaaaeaaa  833
              WQAL      I    WP+ DES L  + +E+VVQ++GK++++L ++ D  +   +  A
Sbjct  743  ELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVA  802

Query  834  ladekVQRFTEGKTVRKVIVVPGKLVNIVAN  864
            LA+EKVQ    GK + KVI VP KLVNIV +
Sbjct  803  LANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

1635) leuS in NC_020912


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  490 bits (1848),  Expect = 2e-139, Method: Compositional matrix adjust.
 Identities = 359/880 (41%), Positives = 542/880 (62%), Gaps = 61/880 (6%)

Query  5    YQPLEIETQAQNYWKEHQSFLVRELPDKEKFYCLSMFPYPSGK-LHMGHVRNYTIGDVIS  63
            Y+   IE + Q +W ++++F     + K KFY L MFPYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYHRMQGRNVLQPMGWDAFGMPAENAAMKNNVAPAAWTYDNIAYMKSQLDSLGLAIDWSR  123
            R+ R QG+NVL+PMGWDAFG+PAE+ AM     PA  T +NIA  K Q+++LG++ DW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVTTCKPDYYRWEQWLFTRLFEKGVIYRKNGTVNWDPVDQTVLANEQVI-DGRGWRSGAL  182
            EV T  P+YY+W QW+FT+L+EKG+ Y  +  VNW     T +ANE+V+ DG + R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  IEKREIPMYYFKITAYAEELLESLDNLPGWPEQVKTMQRNWIGKSRGMEIGFPYDQASIG  242
            + ++ +    +KITAYAE LLE L+++ +WPE +K MQRNWIGKS G ++ F   ++   
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTD--  240

Query  243  HAGQLKVFTTRPDTLMGATYVAVAAEHPLATQAAQNDPQLQAFIDECKRGGVAEADIA--  300
               ++ VFTTRPDTL GATY  +A+EH+L    + +D Q +A + + KR +   +D+A  
Sbjct  241  --KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSD-QAEA-VADYKRQASLKSDLART  296

Query  301  --TQEKKGMATSLFVEHPLTGDKLPVWVANYVLMNYGEGAVMAVPGHDERDFEFANKYGL  358
              ++EK G+ T+ +  +P+ G  +PVW+A+YVL +YG GA+MAVP+HDERD EFA+++ L
Sbjct  297  DLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNL  356

Query  359  PIRQVIAKVEGDDDFESSVWKEWYGAKDESVLTVNSGKYDNLGYQAAFDAIGADLEAKGL  418
             I  V+   + ++           +A  E  L +NS+  D L+  +A+  +   LEA G+
Sbjct  357  DIIPVLEGGNVEE-----------AAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGV  405

Query  419  GQARTQFRLRDWGISRQRYWGCPIPIIHCEACGDVPVPADQlpvvlpedvvpdGSG---S  475
            G+    +RLRDW +SRQRYWG PIPIIH E     +VP  +LP+VLP       SG   S
Sbjct  406  GNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGES  465

Query  476  PLAKMPEFYECSCPKCGQPAKRETDTMDTFVESSWYFARYACPQFEGGMLDKKAADYWLP  535
            PLA++ +  E +    G  ++RET+TM     SSWY+ RY  P+    + D      WLP
Sbjct  466  PLANVTDWLEVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLP  524

Query  536  VDQYIGGIEHAILHLLYARFFHKLMRDEGLVGSDEPFKNLLTQGMVVADTYYRTTANGGK  595
            VD Y+GG EHA+LHLLYARF HK++ D G+V + EPF++L+ QGM+++ + YR       
Sbjct  525  VDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS-YR-------  576

Query  596  DWFNPADVEVERDAKAKVVGARLKSDGQPVEIGGTEKMSKSKNNGVDPQSMIDQYGADTC  655
               ++ +  V  D   K  G+ +  +       +  KMSKS +N V+P+ +++QYGADT 
Sbjct  577  ---DSRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTL  633

Query  656  RLFMMFASPPDMSLEWSDAGVEGANRFLRRVWRLAHA-HVSAGLPGALDVAALNDAQKQV  714
            R++ MF +P D S+ WS+ G+EG+ +FL RV RL  + +++   +GALD           
Sbjct  634  RVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALD-----------  682

Query  715  RRAIHLAIRQASQDVGQHHKFNTAIAAVMTLMNVLEKAPNQDAQDRALIQEGLETVVLLL  774
             +  + +++  +++V ++ KFNTAIA +M ++N  +K       +  L+ +     V L+
Sbjct  683  -KVYNETVKAVTEQV-DQMKFNTAIAQLMVFVNAANK-------EDKLFSDYAKGFVQLI  733

Query  775  APITPHICHVLWGQLGHAEAVID-ARWPSVDESAlvqdtlqlvvqvNGKLRGHIDVAASA  833
            AP++PH+ + LW  L  +   I    WPS DES LV++ +++VVQ++GK+++ + VA   
Sbjct  734  APFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDL  793

Query  834  SREDVEAAARANENVLRFTEGLSIRKVIVVPGKLVNIVAN  873
            SRE+++  A ANE+V     G  I KVI VP KLVNIV +
Sbjct  794  SREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

1636) leuS in NC_008463


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  490 bits (1847),  Expect = 2e-139, Method: Compositional matrix adjust.
 Identities = 359/880 (41%), Positives = 542/880 (62%), Gaps = 61/880 (6%)

Query  5    YQPLEIETQAQNYWKEHQSFLVRELPDKEKFYCLSMFPYPSGK-LHMGHVRNYTIGDVIS  63
            Y+   IE + Q +W ++++F     + K KFY L MFPYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYHRMQGRNVLQPMGWDAFGMPAENAAMKNNVAPAAWTYDNIAYMKSQLDSLGLAIDWSR  123
            R+ R QG+NVL+PMGWDAFG+PAE+ AM     PA  T +NIA  K Q+++LG++ DW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVTTCKPDYYRWEQWLFTRLFEKGVIYRKNGTVNWDPVDQTVLANEQVI-DGRGWRSGAL  182
            EV T  P+YY+W QW+FT+L+EKG+ Y  +  VNW     T +ANE+V+ DG + R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  IEKREIPMYYFKITAYAEELLESLDNLPGWPEQVKTMQRNWIGKSRGMEIGFPYDQASIG  242
            + ++ +    +KITAYAE LLE L+++ +WPE +K MQRNWIGKS G ++ F   ++   
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTD--  240

Query  243  HAGQLKVFTTRPDTLMGATYVAVAAEHPLATQAAQNDPQLQAFIDECKRGGVAEADIA--  300
               ++ VFTTRPDTL GATY  +A+EH+L    + +D Q +A + + KR +   +D+A  
Sbjct  241  --KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSD-QAEA-VADYKRQASLKSDLART  296

Query  301  --TQEKKGMATSLFVEHPLTGDKLPVWVANYVLMNYGEGAVMAVPGHDERDFEFANKYGL  358
              ++EK G+ T+ +  +P+ G  +PVW+A+YVL +YG GA+MAVP+HDERD EFA+++ L
Sbjct  297  DLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNL  356

Query  359  PIRQVIAKVEGDDDFESSVWKEWYGAKDESVLTVNSGKYDNLGYQAAFDAIGADLEAKGL  418
             I  V+   + ++           +A  E  L +NS+  D L+  +A+  +   LEA G+
Sbjct  357  DIIPVLEGGNVEE-----------AAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGV  405

Query  419  GQARTQFRLRDWGISRQRYWGCPIPIIHCEACGDVPVPADQlpvvlpedvvpdGSG---S  475
            G+    +RLRDW +SRQRYWG PIPIIH E     +VP  +LP+VLP       SG   S
Sbjct  406  GNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGES  465

Query  476  PLAKMPEFYECSCPKCGQPAKRETDTMDTFVESSWYFARYACPQFEGGMLDRKAADYWLP  535
            PLA++ +  E +    G  ++RET+TM     SSWY+ RY  P+    + D      WLP
Sbjct  466  PLANVTDWLEVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLP  524

Query  536  VDQYIGGIEHAILHLLYARFFHKLMRDEGLVGSDEPFKNLLTQGMVVADTYYRTTANGGK  595
            VD Y+GG EHA+LHLLYARF HK++ D G+V + EPF++L+ QGM+++ + YR       
Sbjct  525  VDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS-YR-------  576

Query  596  DWFNPADVEVERDAKAKVVGARLKSDGQPVEIGGTEKMSKSKNNGVDPQSMIDQYGADTC  655
               ++ +  V  D   K  G+ +  +       +  KMSKS +N V+P+ +++QYGADT 
Sbjct  577  ---DSRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTL  633

Query  656  RLFMMFASPPDMSLEWSDAGVEGANRFLRRVWRLAHA-HVSAGLPGALDVAALDDAQKQV  714
            R++ MF +P D S+ WS+ G+EG+ +FL RV RL  + +++   +GALD           
Sbjct  634  RVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALD-----------  682

Query  715  RRAIHLAIRQASQDVGQHHKFNTAIAAVMTLMNVLEKAPNQDAQDRALIQEGLETVVLLL  774
             +  + +++  +++V ++ KFNTAIA +M ++N  +K       +  L+ +     V L+
Sbjct  683  -KVYNETVKAVTEQV-DQMKFNTAIAQLMVFVNAANK-------EDKLFSDYAKGFVQLI  733

Query  775  APITPHICHVLWGQLGHAEAVID-ARWPSVDESAlvqdtlqlvvqvNGKLRGHIDVAASA  833
            AP++PH+ + LW  L  +   I    WPS DES LV++ +++VVQ++GK+++ + VA   
Sbjct  734  APFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDL  793

Query  834  SREDVEAAARANENVLRFTEGLSIRKVIVVPGKLVNIVAN  873
            SRE+++  A ANE+V     G  I KVI VP KLVNIV +
Sbjct  794  SREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

1637) leuS [H] in NC_019902


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  490 bits (1847),  Expect = 2e-139, Method: Compositional matrix adjust.
 Identities = 344/850 (41%), Positives = 535/850 (63%), Gaps = 51/850 (6%)

Query  5    YDPAVIETAVQRRWDESRCFDAreddrrerFYCLSMFPYPSGK-LHMGHVRNYTIGDVIA  63
            YD + IE   Q  W +++ F +  D  + +FY L MFPYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RFQRMQGRNVLQPMGWDAFGLPAENAAIQNRVAPAAWTRQNIEQMRAQLKRLGFAYDWSR  123
            RF+R QG+NVL+PMGWDAFGLPAE+ A++    PA  T +NI + + Q++ LGF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EIATCDAEYYRWEQWLFLRLFEKGLVYRKLSTVNWDPVDQTVLANEQVI-DGRGWRSGAV  182
            E+ T D++YY+W QW+F +L+EKGL Y     VNW     T +ANE+V+ DG + R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERREMPQWFLRITdyadellealdgldgWPDQVRAMQRNWIGRSEGVELDFTVAGDQR-  241
            V R+ M QW L+IT    E L       +WP+ ++ MQRNWIG+S G ++ F V + ++ 
Sbjct  184  VVRKPMRQWMLKIT-AYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  242  LTVYTTRPDTLMGVSYVALAPEHPLVTARLGDDPDLAAFVEDCRNRGVAEADLA----TM  297
            +TV+TTRPDTL G +Y  LAPEH+LV A    D   A  V D + ++   +DLA    + 
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEA--VADYKRQASLKSDLARTDLAK  300

Query  298  EKRGRALGITARHPLSGEEVPVWVANFVLMEYGTGAVMAVPAHDERDHAFAQQYGLPIRP  357
            EK G   G  A +P++G E+PVW+A++VL  YGTGA+MAVPAHDERD  FA+Q+ L I P
Sbjct  301  EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIP  360

Query  358  VIEPLDGSRWDFDAAAFTDHGRLVDSGEFSGLDFEQAFTAIAVSLEArglgrrrrnyrlr  417
            V   L+G+  + + AAFT++G  ++S+ + GLD   A++ +   LEA G+G     YRLR
Sbjct  361  V---LEGG--NVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  418  DWGISRQRYWGCPIPVIHCDDCGVVPVPESDLPVRLP--EDVVPDGAG-SPLAKMASFHE  474
            DW +SRQRYWG PIP+IH +D    +VPES+LP+ LP   D+ P G+G SPLA+++   E
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  475  TTCPECGRAARRETDTFDTFFESSWYYARYCSADNHEAMLDAR-ADYWLPVHQYVGGVEH  533
             T  +  + +RRET+T      SSWYY RY  ++N E + D      WLPV+ YVGG EH
Sbjct  476  VTREDGVK-GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEH  534

Query  534  AVLHLLYARFFHKLLRDEGLLSSDEPFTRLLTQGMVIAPTFYRERPDGSRDWINPADVEV  593
            AVLHLLYARF HK+L D G++++ EPF +L+ QGM+++ + YR+         + + +  
Sbjct  535  AVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS-YRD---------SRGALVA  584

Query  594  ARGAEGADDARIRATGERVQIGGMEKMSKSKNNGVDPQALIDRYGADTARLFTMFAAPPD  653
            +   E  D++ ++         +  KMSKS +N V+P+ ++++YGADT R++ MF +P D
Sbjct  585  TDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLD  644

Query  654  LSLEWSDSGVEGAHRFLKRLWRQVFECRCTQATPMRPDTARLGDTGRALRRKLHETIAKV  713
             S+ WS+ G+EG+++FL R+ R +     T+            + + AL +  +ET+  V
Sbjct  645  ASIAWSEEGLEGSRKFLDRVYRLITTKEITE------------ENSGALDKVYNETVKAV  692

Query  714  TDDIGRRQTFNTAIAACMELLNELSRLPAGEPEANPLRRECLTDLVLMLAPIVPHISQAL  773
            T+++++ + FNTAIA  M ++N  ++        + L  +   ++V ++AP+ PH+++ L
Sbjct  693  TEQVDQMK-FNTAIAQLMVFVNAANK-------EDKLFSDYAKGFVQLIAPFAPHLGEEL  744

Query  774  WESMGHHG-LIADAAWPAVDPEALTVAEITLAVQVNGKLRAQIQVPAEAPREVIEQAARG  832
            W+++   G  I+  +WP+ D   L   ++ + VQ++GK++A++ V+ + +RE +++ A +
Sbjct  745  WQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALA  804

Query  833  DANVRRHLEG  842
            + +V+ ++ G
Sbjct  805  NEKVQAEIAG  814

1638) MycrhN_1794 in NC_016604


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  490 bits (1846),  Expect = 3e-139, Method: Compositional matrix adjust.
 Identities = 341/742 (46%), Positives = 486/742 (66%), Gaps = 62/742 (8%)

Query  234  LVYRADSLVNWCPGLGTVLANEEVTSDGRSERGNFPVFRKRLRQWMMRITAYSdrllddl  293
            L Y A+  VNW   LGT +ANEEV +DG SERG +PV RK +RQWM++ITAY++RLL+DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  294  dlldWPDKVKTMQRNWIGRSTGASVQFGTDAGDIE--VFTTRPDTLFGATYLVLAPEHEL  351
            + +DWP+ +K MQRNWIG+STGA+V F     D +  VFTTRPDTLFGATY VLAPEH L
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  352  VDALVAEQWPADVDSRWTFGGATPAEAVAAYRTSVAAKSDLERQE-NKTKTGVFLGAYAT  410
            VDA+ + +                AEAVA Y+   + KSDL R +  K KTGV  G+YA 
Sbjct  268  VDAITTSD---------------QAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAI  312

Query  411  NPADGKQVPVFIADYVLLGYGTGAIMAVPGHDQRDWDFAGEFGLPIVEVIAGGDISAQAY  470
            NP +GK++PV IADYVL +YGTGAIMAVP+HD+RDW+FA +F L I+ V+ GG++   A+
Sbjct  313  NPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEAAF  372

Query  471  SGDGELVNSDYLNGLSVASAKEAITNRLVADGRGQARVEYKLRDWLFARQRYWGEPFPIV  530
            + DG  +NSD+L+GL  ASA   + ++L A+G G+  V Y+LRDWLF+RQRYWGEP+PI+
Sbjct  373  TEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPII  432

Query  531  YDAEGRAHPLPESALPVELPDIPDYAPVQFdpddaasepsppLGKATDWVNVELDLGDGL  590
               +G + ++PES LP+ LP   D  P        ++   +PL++ TDW++V  +  DG+
Sbjct  433  HWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTDWLEVTRE--DGV  482

Query  591  KPYTRDTNVMPQWAASSWYELRYTDPYNKEALCAKENEAYWMGPRPAEHGHNDPGGVDLY  650
            K   R+TN MPQWA+SSWY LRY DP N E L   E    W+              VD+Y
Sbjct  483  KG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWL-------------PVDIY  528

Query  651  VGGVEHAVLHLLYCRFWHKVLFDLGHVSSREPYRRLVNQGYIQAFAYTDARGAYVPAAEV  710
            VGG EHAVLHLLY RFWHKVL+DLG V+++EP+++L NQG I + +Y D+RGA V++  V
Sbjct  529  VGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKV  588

Query  711  TERDGSFYWLPPNVADGSAPGPDGEIEVFQEFGKIGKSLKNSVSPDEICGDYGADTLRVY  770
              RDGSF+    + ++    +P          +K++KSLKN V+PD++  +YGADTLRVY
Sbjct  589  EKRDGSFF--HVETGEELEQAP----------AKMSKSLKNVVNPDDVVEQYGADTLRVY  636

Query  771  EMSMGPLDASRPWATKDVVGAYRFLQRVWRLVVDEQSGSaravddaaldddtlrllHRTI  830
            EM MGPLDAS +W+  ++ G+ +FL+RV RL+   +             +   ++ + T+
Sbjct  637  EMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITE-------ENSGALDKVYNETV  689

Query  831  AGVSDDYTNLRNNTAAAKLIEYTNHLTKQGVTARAALEPLVLMVAPLAPHLAEELWRRL-  889
             +V+++  +++ NTA A+L+ + N   K++         +V ++AP+APHL+EELW+ L 
Sbjct  690  KAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALT  749

Query  890  GHDTSLAHGPFPMADPQYLVQDTIELPVQVNGKVRGRITVaadadadaleaaaladaKVQ  949
            + + S++  P P  D   LV++ +E+ VQ++GKV++++ VA D   + L+  ALA+ KVQ
Sbjct  750  ASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQ  809

Query  950  EFLNGATPKKVIVVAGRLVNVV  971
              + G    KVI V+ +LVN+V
Sbjct  810  AEIAGKDIIKVIAVPNKLVNIV  831


 Score =  133 bits (488),  Expect = 5e-32, Method: Compositional matrix adjust.
 Identities = 77/149 (52%), Positives = 98/149 (66%), Gaps = 10/149 (6%)

Query  36   GEIERAWQQTWADRGTFNVPNPVGSLSVPGGAVPADKMFVQDMFPYPSGEGLHVGHPLGY  95
              IE  WQ  WAD  TF+           G   +  K +  DMFPYPSG GLHVGHP GY
Sbjct  7    TAIEPKWQAFWADNHTFK----------TGTDASKPKFYALDMFPYPSGAGLHVGHPEGY  56

Query  96   IATDVYARYYRMSGRNVLHALGFDAFGLPAEQYAIQTGTHPRTRTEANIVNFRRQLGRLG  155
             ATD+ +R+ R  G+NVLH++G DAFGLPAEQYA++TG +P   T  NI NF+RQ+  LG
Sbjct  57   TATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALG  116

Query  156  FGHDSRRSFSTTDVDFYKWTQWIFLQIYN  184
            F+ D  R  +TTD ++YKWTQWIF ++Y+
Sbjct  117  FSYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1639) leuS in NC_005085


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  489 bits (1844),  Expect = 3e-139, Method: Compositional matrix adjust.
 Identities = 346/855 (41%), Positives = 538/855 (63%), Gaps = 61/855 (7%)

Query  29   DASRPKYYALSMFPYPSGK-LHMGHVRNYTITDVLARFKRLQGFNVLQPMGWDAFGLPAE  87
            DAS+PK+YAL MFPYPSG  LH+GH   YT TD+L+RFKR QG NVL+PMGWDAFGLPAE
Sbjct  28   DASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSRFKRAQGHNVLHPMGWDAFGLPAE  87

Query  88   NAAMKNGGAPAAWTYANIEYMKTQLDSLGFALDWERELATCKPDYYRWEQWLFTRLFEKG  147
            + AM  G  PA  T  NI   K Q+++LGF+ DW+RE+ T  P+YY+W QW+FT+L+EKG
Sbjct  88   QYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKG  147

Query  148  VIYKKNGVVNW-DPVDQTVLANEQVVDGRGWRSGALVEKREIPMYYFRITDYAEQLLADL  206
            + Y  +  VNW + ++ ++  +E + DG + R+G  V ++ +    ++IT YAE+LL DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  207  DKLDGWPEQVKTMQRNWIGKSYGSDVVFPYDEASIGHAGELKVYTTRPDTLMGATYVAVA  266
            + +D WPE +K MQRNWIGKS G++V F   ++      ++ V+TTRPDTL GATY  +A
Sbjct  208  EEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTD----KDFTVFTTRPDTLFGATYAVLA  262

Query  267  AEHPLatqaaagnaalqafiaECKSGSVAEADVAK----MEKKGMDTGLSVIHPLTGERL  322
            +EH+L    A   +     +A+ K  +   +D+A+     EK G+ TG   I+P+ G  +
Sbjct  263  PEHAL--VDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAINPVNGKEM  320

Query  323  PVWVANYVLWGYGEGAVMAVPAHDERDFEFANKYQLPIKQVIALASGDGEYDAANWQEWY  382
            PVW+A+YVL +YG GA+MAVPAHDERD EFA++++L I  V+  ++ +            
Sbjct  321  PVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEA----------  370

Query  383  GAKDDTVKTVNSGKYDGLGYQAAFDAIIGDLQAKSLGQKKTQYRLRDWGISRQRYWGCPI  442
            +  +D +  +NS+  DGL+  +A+  ++  L+A ++G+ +  YRLRDW +SRQRYWG PI
Sbjct  371  AFTEDGLH-INSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPI  429

Query  443  PIIHCPSCGDVPVPEKDLPVTLP--ENVIPDGAG-SPLAKMPEFYETSCPKCGGAAKRET  499
            PIIH       +VPE +LP+ LP   ++ P G+G SPLA++ +  E +    G  ++RET
Sbjct  430  PIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED-GVKGRRET  488

Query  500  DTMDTFVESSWYYARYASPKCDTAMVDKQAADYWLQVDQYVGGIEHAILHLLYARFFHKL  559
            +TM     SSWYY RY  P     + D +    WL VD YVGG EHA+LHLLYARF HK+
Sbjct  489  NTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWHKV  548

Query  560  MRDEGLVSSDEPFKSLLTQGMVVCETFYRDLPNGTKDWIAPQDVILERDAKGKIVAAKHR  619
            + D G+V++ EPF+ L+ QGM++  + YRD          +++ ++  D   K  ++  +
Sbjct  549  LYDLGVVPTKEPFQKLFNQGMILGTS-YRD----------SRGALVATDKVEKRDGSFFH  597

Query  620  VDGQPVVVGGIEKMSKSKNNGVDPQEFIEKYGADTARLFMMFAAPPEQSLEWSDAGVEGA  679
            V+    +  +  KMSKS +N V+P++ +E+YGADT R++ MF +P + S+ WS+ G+EG+
Sbjct  598  VETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGS  657

Query  680  FRFLKRLWKTAREHVEAGVVAPYASGELNASQKELRFKLHGTIQKVADDYGRRQQFNTAI  739
             +FL R+ +     + +  ++   SG L+        K+     K   +   + +FNTAI
Sbjct  658  RKFLDRVYRL----ITTKEITEENSGALD--------KVYNETVKAVTEQVDQMKFNTAI  705

Query  740  AAVMELLNAYDKADTS-GDIGRAVAQEVLEAATLLLSPIVPHVCDGIWNALKPGTELLA-  797
            A +M ++NA +K D   +D +++  Q        L++P+ PH+ + +W+AL ++ E ++ 
Sbjct  706  AQLMVFVNAANKEDKLFSDYAKGFVQ--------LIAPFAPHLGEELWQALTASGESISY  757

Query  798  QAWPKVDEAALVKSEIELMVQVCGKLRGSVTVaadaakdaieaaalaHENVIKFMEGKPA  857
             +WP  DE+ LV +++E++VQ+ GK+++ + VA D +++ ++  ALA+E+V   + GK  
Sbjct  758  VPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDI  817

Query  858  KKIIVVPGRLVNIVV  872
             K+I VP +LVNIV+
Sbjct  818  IKVIAVPNKLVNIVI  832

1640) leuS in NC_017517


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  489 bits (1843),  Expect = 4e-139, Method: Compositional matrix adjust.
 Identities = 362/886 (41%), Positives = 534/886 (61%), Gaps = 71/886 (8%)

Query  5    YRPAAIEPAAQKKWDDARIFNVSEDASKPKYYCLSMFPYPSGK-LHMGHVRNYTIGDVLS  63
            Y  +AIEP  Q  W D + F+ + DASKPK+Y L MFPYPSG  LH+GH   YT  D+LS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RFKRLNGFNVMQPMGWDAFGMPAENAAMKHNVAPAAWTYDNIEYMKTQLKSLGFAIDWER  123
            RFKR +G NV++PMGWDAFG+PAE+ AM     PA  T +NI   K Q+++LGF+ DW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ETATCKPEYYRWEQWLFTKLFEKGIVYRKNGTVNWDPVDQTVLANEQVI-DGRGWRSGAL  182
            E  T  P+YY+W QW+FTKL+EKG+ Y  +  VNW     T +ANE+V+ DG + R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  IEKREIPMYYFKITDYAEELLNDLDKLEHWPEQVKTMQRNWIGKSRGMTVRFAVSDDSKQ  242
            + ++ +    +KIT YAE LL+DL+ ++ WPE +K MQRNWIGKS G  V F V D  K+
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  GLEGDYAKFLQVYTTRPDTLMGATYVavaaehplataaaaDKPELQAFIAECKAGSVAEA  302
                     + V+TTRPDTL GATY         A   A   ++    +A+ K  +   +
Sbjct  243  ---------FTVFTTRPDTLFGATYA--VLAPEHALVDAITTSDQAEAVADYKRQASLKS  291

Query  303  DMA----TMEKKGVPTGRYVVNPLNGDKLEVWIANYVLWGYGDGAVMAVPAHDERDFEFA  358
            D+A    + EK GV TG Y +NP+NG  + VWIA+YVL +YG GA+MAVPAHDERD EFA
Sbjct  292  DLARTDLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFA  351

Query  359  TKYNLPKKQVI---AVGDNAFDENQWQEWYGDKENGVLVNSGDLDGLDFQTAFDAVAAKL  415
             ++NL    V+    V + AF            E+G+ +NS+ LDGLD  +A+  +   L
Sbjct  352  KQFNLDIIPVLEGGNVEEAAF-----------TEDGLHINSDFLDGLDKASAIAKMVEWL  400

Query  416  QSQGAGEPKTQYRLRDWGISRQRYWGCPIPIVHCEQCGDVPVPADQLPVVLP--ENVVPD  473
            +++G G+ +  YRLRDW +SRQRYWG PIPI+H E+    +VP  +LP+VLP   ++ P 
Sbjct  401  EAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPS  460

Query  474  GMG-SPLAKMPEFYETACPCCGGAAKRETDTMDTFMESSWYFFRYMSPKFSDGMVSAEAA  532
            G G SPLA++ +  E +    G  ++RET+TM     SSWY++RY+ P  ++ +   E  
Sbjct  461  GTGESPLANVTDWLEVTRE-DGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELL  519

Query  533  KYWGAVDQYIGGIEHAILHLLYARFFTKLMRDEGLVNVGEPFERLLTQGMVVCETYYREN  592
            K W +VD Y+GG EHA+LHLLYARF  K++ D G+V   EPF++L+ QGM++  +Y   +
Sbjct  520  KQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY--RD  577

Query  593  DKGGKDWINPADVELTFDDKGRPISAVLKADGLPVVISGTEKMSKSKNNGVDPQELINAY  652
             +G+   +    VE       +  ++ +  +    +  +  KMSKS +N V+P+++++ Y
Sbjct  578  SRGAL--VATDKVE-------KRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQY  628

Query  653  GADTARLFMMFAAPPEQSLEWSDSGVEGAHRFLRRLWRTVYEYLKQGEAVKAFAGSQDGL  712
            GADT R++ MF +P + S+ WS+ G+EG+++FL R    VY  +   E     +G+ D  
Sbjct  629  GADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR----VYRLITTKEITEENSGALD--  682

Query  713  SKELKDLRHKLHATTAKVSDDYGRRQQFNTAIAAVMELLNQYDKTDTGGEQGRAVAQEVL  772
                     K+   T K   +   + +FNTAIA +M ++N  +K D        +  +  
Sbjct  683  ---------KVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK-------LFSDYA  726

Query  773  ETAVRLLWPIVPHICETLWSEL--NGAKLWEAGWPTVDEAALVKSEIEVMVQVNGKLRGK  830
               V+L+ P+ PH+ E LW  L  +G  +    WP+ DE+ LV +++E++VQ++GK+++K
Sbjct  727  KGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAK  786

Query  831  ITvaadaskadleaaalategavkFMEGKPAKKIIVVPGRLVNIVV  876
            + VA D S+ +L+  ALA E     + GK   K+I VP +LVNIV+
Sbjct  787  LVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

1641) leuS in NC_011770


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  489 bits (1842),  Expect = 4e-139, Method: Compositional matrix adjust.
 Identities = 359/880 (41%), Positives = 541/880 (62%), Gaps = 61/880 (6%)

Query  5    YQPLEIETQAQNYWKEHQSFLVRELPDKEKFYCLSMFPYPSGK-LHMGHVRNYTIGDVIS  63
            Y+   IE + Q +W ++++F     + K KFY L MFPYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYHRMQGRNVLQPMGWDAFGMPAENAAMKNNVAPAAWTYDNIAYMKSQLDSLGLAIDWSR  123
            R+ R QG+NVL+PMGWDAFG+PAE+ AM     PA  T +NIA  K Q+++LG++ DW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVTTCKPDYYRWEQWLFTRLFEKGVIYRKNGTVNWDPVDQTVLANEQVI-DGRGWRSGAL  182
            EV T  P+YY+W QW+FT+L+EKG+ Y  +  VNW     T +ANE+V+ DG + R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  IEKREIPMYYFKITAYAEELLESLDNLPGWPEQVKTMQRNWIGKSRGMEIGFPYDQASIG  242
            + ++ +    +KITAYAE LLE L+++ +WPE +K MQRNWIGKS G ++ F   ++   
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTD--  240

Query  243  HAGQLKVFTTRPDTLMGATYVAVAAEHPLATQAAQNDPQLQAFIDECKRGGVAEADIA--  300
               ++ VFTTRPDTL GATY  +A+EH+L    + +D Q +A + + KR +   +D+A  
Sbjct  241  --KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSD-QAEA-VADYKRQASLKSDLART  296

Query  301  --TQEKKGMATSLFVEHPLTGDKLPVWVANYVLMNYGEGAVMAVPGHDERDFEFANKYGL  358
              ++EK G+ T+ +  +P+ G  +PVW+A+YVL +YG GA+MAVP+HDERD EFA+++ L
Sbjct  297  DLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNL  356

Query  359  PIRQVIAKVEGDNDFESSVWKEWYGAKDESVLTVNSGKYDNLGYQAAFDAIGADLEAKGL  418
             I  V+   + ++           +A  E  L +NS+  D L+  +A+  +   LEA G+
Sbjct  357  DIIPVLEGGNVEE-----------AAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGV  405

Query  419  GQARTQFRLRDWGISRQRYWGCPIPIIHCEACGDVPVPADQlpvvlpedvvpdGSG---S  475
            G+    +RLRDW +SRQRYWG PIPIIH E     +VP  +LP+VLP       SG   S
Sbjct  406  GNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGES  465

Query  476  PLAKMPEFYECNCPKCGQPAKRETDTMDTFVESSWYFARYACPQFEGGMLDRKAADYWLP  535
            PLA++ +  E      G  ++RET+TM     SSWY+ RY  P+    + D      WLP
Sbjct  466  PLANVTDWLEVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLP  524

Query  536  VDQYIGGIEHAILHLLYARFFHKLMRDEGLVGSDEPFKNLLTQGMVVADTYYRTTANGGK  595
            VD Y+GG EHA+LHLLYARF HK++ D G+V + EPF++L+ QGM+++ + YR       
Sbjct  525  VDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS-YR-------  576

Query  596  DWFNPADVEVERDAKAKVVGARLKSDGQPVEIGGTEKMSKSKNNGVDPQSMIDQYGADTC  655
               ++ +  V  D   K  G+ +  +       +  KMSKS +N V+P+ +++QYGADT 
Sbjct  577  ---DSRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTL  633

Query  656  RLFMMFASPPDMSLEWSDAGVEGANRFLRRVWRLAHA-HVSAGLPGALDVATLSDAQKQV  714
            R++ MF +P D S+ WS+ G+EG+ +FL RV RL  + +++   +GALD           
Sbjct  634  RVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALD-----------  682

Query  715  RRAIHLAIRQASQDVGQHHKFNTAIAAVMTLMNVLEKAPNQDAQDRALIQEGLETVVLLL  774
             +  + +++  +++V ++ KFNTAIA +M ++N  +K       +  L+ +     V L+
Sbjct  683  -KVYNETVKAVTEQV-DQMKFNTAIAQLMVFVNAANK-------EDKLFSDYAKGFVQLI  733

Query  775  APITPHICHVLWGQLGHAEAVID-ARWPSVDESAlvqdtlqlvvqvNGKLRGHIDVAASA  833
            AP++PH+ + LW  L  +   I    WPS DES LV++ +++VVQ++GK+++ + VA   
Sbjct  734  APFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDL  793

Query  834  SREDVEAAARANENVLRFTEGLSIRKVIVVPGKLVNIVAN  873
            SRE+++  A ANE+V     G  I KVI VP KLVNIV +
Sbjct  794  SREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

1642) leuS in NC_012559


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  489 bits (1842),  Expect = 5e-139, Method: Compositional matrix adjust.
 Identities = 353/873 (41%), Positives = 548/873 (63%), Gaps = 55/873 (6%)

Query  5    YQPRDIEVAAQQKWEKTAAFKAVEDASRPKYYCLSMFPYPSGK-LHMGHVRNYTIGDVLS  63
            Y+   IE   Q  W    +FK+  DAS+PK+Y L MFPYPSG  LH+GH   YT  D+LS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYMALKGYNVLQPMGWDAFGMPAENAALKNQVAPAAWTYSNIEYMKTQLKSLGFAIDWER  123
            R+   +G NVL+PMGWDAFG+PAE+ A+     PA  T  NI   K Q+++LGF+ DW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVTTCKPDYYRWEQWLFTRLFEKGVIYRKNGVVNWDPVDQTVLANEQVI-DGRGWRSGAL  182
            EV T  P+YY+W QW+FT+L+EKG+ Y  +  VNW     T +ANE+V+ DG + R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VEKREIPMYYFGITQYadelladldtldWPPQVATMQRNWIGKSFGADVRFAYDEASIGS  242
            V ++ +    + IT YA+ LL DL+ +DWP  +  MQRNWIGKS GA+V F   +    +
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKD----T  239

Query  243  AGELTVYTTRPDTLMGATYVAVAAEHPLATQAAANDPALQAFIAKCKAGSVAEADMA---  299
              ++TV+TTRPDTL GATY  +A+EH+L    +++D A    +A  K  +   +D+A   
Sbjct  240  DKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQA--EAVADYKRQASLKSDLARTD  297

Query  300  -TMEKEGMPTGLFVVHPLTGAKLPVWVANYVLMSYGSGAVMAVPAHDERDFAFANKYALP  358
             + EK G+ TG + ++P+ G  +PVW+A+YVL SYG+GA+MAVPAHDERD  FA+++ L 
Sbjct  298  LAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNL-  356

Query  359  IQQVIALKEGDATFDASTWQDWYATKDDSTRLVNSGKYDGLDFQGafdaivadlaakaaG  418
              ++I++ EG+   +A+     ++   +    +NS+  DGLD  +A+  +V  L A + G
Sbjct  357  --DIIPVLEGGNVEEAA-----FT---EDGLHINSDFLDGLDKASAIAKMVEWLEAEGVG  406

Query  419  EKKTQYRLRDWGISRQRYWGCPIPIIHCDSCGDVPVPADQLPVVLP--ENVVPDGSGN-P  475
            + +  YRLRDW +SRQRYWG PIPIIH +     +VP  +LP+VLP   ++ P G+G+ P
Sbjct  407  NENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESP  466

Query  476  LAKMPEFYETTCPCCGKPARRETDTMDTFVESSWYFARYASPDCATGMVDDR-ARYWLNV  534
            LA++ +  E T     K +RRET+TM     SSWY+ RY  P+ +  + D+   + WL V
Sbjct  467  LANVTDWLEVTREDGVK-GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPV  525

Query  535  DQYIGGIEHAILHLLYARFFNKLMRDEGLLANDEPFQRLLTQGMVVCETFYRDLDNGSKE  594
            D Y+GG EHA+LHLLYARF +K++ D G+++  EPFQ+L+ QGM++  + YRD   +   
Sbjct  526  DIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS-YRDSRGA---  581

Query  595  WITPADVVIERDGKGKIIAATHKADGLPVVVGGIEKMSKSKNNGVDPQALIEQYGADTAR  654
             + ++D V  RDG    + + +  +  P       KMSKS +N V+P+ ++EQYGADT R
Sbjct  582  -LVATDKVEKRDGSFFHVETGEELEQAPA------KMSKSLKNVVNPDDVVEQYGADTLR  634

Query  655  LFMMFAAPPSQSLEWSDAGVEGAYRFLKRLYKIVSEYVAGGVAERFVAGELTADEKALRL  714
            ++ MF +P   S+ WS+ G+EG+ +FL R+Y++++            + E+T ++ +   
Sbjct  635  VYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLIT------------TKEITEENSGALD  682

Query  715  KLHTTIQKVSDDFGVRQQFNTAIAAVMELLNLFDRTEASRAVRQevlesvvvllsPIVPH  774
            K+     K   +   + +FNTAIA +M ++N  ++ +    +  +   + V L++P+ PH
Sbjct  683  KVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKED---KLFSDYAKGFVQLIAPFAPH  739

Query  775  ICETLWSALKPGSELLA-QRWPEVDPAALVQDEIELVVQVNGKLRGSVRVAADAGRDVIE  833
            + E LW AL +++E ++   WP  D + LV++++E+VVQ++GK+++ + VA D +R+ ++
Sbjct  740  LGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQ  799

Query  834  AAALAHEQVRKFMDGQPAKKVIVVPGRLVNIVV  866
              ALA+E+V+  + G+   KVI VP +LVNIV+
Sbjct  800  EVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

1643) leuS in NC_018080


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  489 bits (1842),  Expect = 5e-139, Method: Compositional matrix adjust.
 Identities = 359/880 (41%), Positives = 541/880 (62%), Gaps = 61/880 (6%)

Query  5    YQPLEIETQAQNYWKEHQSFLVRELPDKEKFYCLSMFPYPSGK-LHMGHVRNYTIGDVIS  63
            Y+   IE + Q +W ++++F     + K KFY L MFPYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYHRMQGRNVLQPMGWDAFGMPAENAAMKNNVAPAAWTYDNIAYMKSQLDSLGLAIDWSR  123
            R+ R QG+NVL+PMGWDAFG+PAE+ AM     PA  T +NIA  K Q+++LG++ DW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVTTCKPDYYRWEQWLFTRLFEKGVIYRKNGTVNWDPVDQTVLANEQVI-DGRGWRSGAL  182
            EV T  P+YY+W QW+FT+L+EKG+ Y  +  VNW     T +ANE+V+ DG + R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  IEKREIPMYYFKITAYAEELLESLDNLPGWPEQVKTMQRNWIGKSRGMEIGFPYDQASIG  242
            + ++ +    +KITAYAE LLE L+++ +WPE +K MQRNWIGKS G ++ F   ++   
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTD--  240

Query  243  HAGQLKVFTTRPDTLMGATYVAVAAEHPLATQAAQNDPQLQAFIDECKRGGVAEADIA--  300
               ++ VFTTRPDTL GATY  +A+EH+L    + +D Q +A + + KR +   +D+A  
Sbjct  241  --KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSD-QAEA-VADYKRQASLKSDLART  296

Query  301  --TQEKKGMATSLFVEHPLTGDKLPVWVANYVLMNYGEGAVMAVPGHDERDFEFANKYGL  358
              ++EK G+ T+ +  +P+ G  +PVW+A+YVL +YG GA+MAVP+HDERD EFA+++ L
Sbjct  297  DLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNL  356

Query  359  PIRQVIAKVEGDNDFESSVWKEWYGAKDESVLTVNSGKYDNLGYQAAFDAIGADLEAKGL  418
             I  V+   + ++           +A  E  L +NS+  D L+  +A+  +   LEA G+
Sbjct  357  DIIPVLEGGNVEE-----------AAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGV  405

Query  419  GQARTQFRLRDWGISRQRYWGCPIPIIHCEACGDVPVPADQlpvvlpedvvpdGSG---S  475
            G+    +RLRDW +SRQRYWG PIPIIH E     +VP  +LP+VLP       SG   S
Sbjct  406  GNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGES  465

Query  476  PLAKMPEFYECNCPKCGQPAKRETDTMDTFVESSWYFARYACPQFEGGMLDRKAADYWLP  535
            PLA++ +  E      G  ++RET+TM     SSWY+ RY  P+    + D      WLP
Sbjct  466  PLANVTDWLEVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLP  524

Query  536  VDQYIGGIEHAILHLLYARFFHKLMRDEGLVGSDEPFKNLLTQGMVVADTYYRTTANGGK  595
            VD Y+GG EHA+LHLLYARF HK++ D G+V + EPF++L+ QGM+++ + YR       
Sbjct  525  VDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS-YR-------  576

Query  596  DWFNPADVEVERDAKAKVVGARLKSDGQPVEIGGTEKMSKSKNNGVDPQSMIDQYGADTC  655
               ++ +  V  D   K  G+ +  +       +  KMSKS +N V+P+ +++QYGADT 
Sbjct  577  ---DSRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTL  633

Query  656  RLFMMFASPPDMSLEWSDAGVEGANRFLRRVWRLAHA-HVSAGLPGALDVAALSDAQKQV  714
            R++ MF +P D S+ WS+ G+EG+ +FL RV RL  + +++   +GALD           
Sbjct  634  RVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALD-----------  682

Query  715  RRAIHLAIRQASQDVGQHHKFNTAIAAVMTLMNVLEKAPNQDAQDRALIQEGLETVVLLL  774
             +  + +++  +++V ++ KFNTAIA +M ++N  +K       +  L+ +     V L+
Sbjct  683  -KVYNETVKAVTEQV-DQMKFNTAIAQLMVFVNAANK-------EDKLFSDYAKGFVQLI  733

Query  775  APITPHICHVLWGQLGHAEAVID-ARWPSVDESAlvqdtlqlvvqvNGKLRGHIDVAASA  833
            AP++PH+ + LW  L  +   I    WPS DES LV++ +++VVQ++GK+++ + VA   
Sbjct  734  APFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDL  793

Query  834  SREDVEAAARANENVLRFTEGLSIRKVIVVPGKLVNIVAN  873
            SRE+++  A ANE+V     G  I KVI VP KLVNIV +
Sbjct  794  SREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

1644) leuS in NC_017548


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  489 bits (1842),  Expect = 5e-139, Method: Compositional matrix adjust.
 Identities = 359/880 (41%), Positives = 541/880 (62%), Gaps = 61/880 (6%)

Query  5    YQPLEIETQAQNYWKEHQSFLVRELPDKEKFYCLSMFPYPSGK-LHMGHVRNYTIGDVIS  63
            Y+   IE + Q +W ++++F     + K KFY L MFPYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYHRMQGRNVLQPMGWDAFGMPAENAAMKNNVAPAAWTYDNIAYMKSQLDSLGLAIDWSR  123
            R+ R QG+NVL+PMGWDAFG+PAE+ AM     PA  T +NIA  K Q+++LG++ DW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVTTCKPDYYRWEQWLFTRLFEKGVIYRKNGTVNWDPVDQTVLANEQVI-DGRGWRSGAL  182
            EV T  P+YY+W QW+FT+L+EKG+ Y  +  VNW     T +ANE+V+ DG + R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  IEKREIPMYYFKITAYAEELLESLDNLPGWPEQVKTMQRNWIGKSRGMEIGFPYDQASIG  242
            + ++ +    +KITAYAE LLE L+++ +WPE +K MQRNWIGKS G ++ F   ++   
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTD--  240

Query  243  HAGQLKVFTTRPDTLMGATYVAVAAEHPLATQAAQNDPQLQAFIDECKRGGVAEADIA--  300
               ++ VFTTRPDTL GATY  +A+EH+L    + +D Q +A + + KR +   +D+A  
Sbjct  241  --KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSD-QAEA-VADYKRQASLKSDLART  296

Query  301  --TQEKKGMATSLFVEHPLTGDKLPVWVANYVLMNYGEGAVMAVPGHDERDFEFANKYGL  358
              ++EK G+ T+ +  +P+ G  +PVW+A+YVL +YG GA+MAVP+HDERD EFA+++ L
Sbjct  297  DLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNL  356

Query  359  PIRQVIAKVEGDNDFESSVWKEWYGAKDESVLTVNSGKYDNLGYQAAFDAIGADLEAKGL  418
             I  V+   + ++           +A  E  L +NS+  D L+  +A+  +   LEA G+
Sbjct  357  DIIPVLEGGNVEE-----------AAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGV  405

Query  419  GQARTQFRLRDWGISRQRYWGCPIPIIHCEACGDVPVPADQlpvvlpedvvpdGSG---S  475
            G+    +RLRDW +SRQRYWG PIPIIH E     +VP  +LP+VLP       SG   S
Sbjct  406  GNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGES  465

Query  476  PLAKMPEFYECNCPKCGQPAKRETDTMDTFVESSWYFARYACPQFEGGMLDRKAADYWLP  535
            PLA++ +  E      G  ++RET+TM     SSWY+ RY  P+    + D      WLP
Sbjct  466  PLANVTDWLEVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLP  524

Query  536  VDQYIGGIEHAILHLLYARFFHKLMRDEGLVGSDEPFKNLLTQGMVVADTYYRTTANGGK  595
            VD Y+GG EHA+LHLLYARF HK++ D G+V + EPF++L+ QGM+++ + YR       
Sbjct  525  VDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS-YR-------  576

Query  596  DWFNPADVEVERDAKAKVVGARLKSDGQPVEIGGTEKMSKSKNNGVDPQSMIDQYGADTC  655
               ++ +  V  D   K  G+ +  +       +  KMSKS +N V+P+ +++QYGADT 
Sbjct  577  ---DSRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTL  633

Query  656  RLFMMFASPPDMSLEWSDAGVEGANRFLRRVWRLAHA-HVSAGLPGALDVAALSDAQKQV  714
            R++ MF +P D S+ WS+ G+EG+ +FL RV RL  + +++   +GALD           
Sbjct  634  RVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALD-----------  682

Query  715  RRAIHLAIRQASQDVGQHHKFNTAIAAVMTLMNVLEKAPNQDAQDRALIQEGLETVVLLL  774
             +  + +++  +++V ++ KFNTAIA +M ++N  +K       +  L+ +     V L+
Sbjct  683  -KVYNETVKAVTEQV-DQMKFNTAIAQLMVFVNAANK-------EDKLFSDYAKGFVQLI  733

Query  775  APITPHICHVLWGQLGHAEAVID-ARWPSVDESAlvqdtlqlvvqvNGKLRGHIDVAASA  833
            AP++PH+ + LW  L  +   I    WPS DES LV++ +++VVQ++GK+++ + VA   
Sbjct  734  APFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDL  793

Query  834  SREDVEAAARANENVLRFTEGLSIRKVIVVPGKLVNIVAN  873
            SRE+++  A ANE+V     G  I KVI VP KLVNIV +
Sbjct  794  SREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

1645) leuS in NC_002516


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  489 bits (1842),  Expect = 5e-139, Method: Compositional matrix adjust.
 Identities = 359/880 (41%), Positives = 541/880 (62%), Gaps = 61/880 (6%)

Query  5    YQPLEIETQAQNYWKEHQSFLVRELPDKEKFYCLSMFPYPSGK-LHMGHVRNYTIGDVIS  63
            Y+   IE + Q +W ++++F     + K KFY L MFPYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYHRMQGRNVLQPMGWDAFGMPAENAAMKNNVAPAAWTYDNIAYMKSQLDSLGLAIDWSR  123
            R+ R QG+NVL+PMGWDAFG+PAE+ AM     PA  T +NIA  K Q+++LG++ DW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVTTCKPDYYRWEQWLFTRLFEKGVIYRKNGTVNWDPVDQTVLANEQVI-DGRGWRSGAL  182
            EV T  P+YY+W QW+FT+L+EKG+ Y  +  VNW     T +ANE+V+ DG + R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  IEKREIPMYYFKITAYAEELLESLDNLPGWPEQVKTMQRNWIGKSRGMEIGFPYDQASIG  242
            + ++ +    +KITAYAE LLE L+++ +WPE +K MQRNWIGKS G ++ F   ++   
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTD--  240

Query  243  HAGQLKVFTTRPDTLMGATYVAVAAEHPLATQAAQNDPQLQAFIDECKRGGVAEADIA--  300
               ++ VFTTRPDTL GATY  +A+EH+L    + +D Q +A + + KR +   +D+A  
Sbjct  241  --KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSD-QAEA-VADYKRQASLKSDLART  296

Query  301  --TQEKKGMATSLFVEHPLTGDKLPVWVANYVLMNYGEGAVMAVPGHDERDFEFANKYGL  358
              ++EK G+ T+ +  +P+ G  +PVW+A+YVL +YG GA+MAVP+HDERD EFA+++ L
Sbjct  297  DLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNL  356

Query  359  PIRQVIAKVEGDNDFESSVWKEWYGAKDESVLTVNSGKYDNLGYQAAFDAIGADLEAKGL  418
             I  V+   + ++           +A  E  L +NS+  D L+  +A+  +   LEA G+
Sbjct  357  DIIPVLEGGNVEE-----------AAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGV  405

Query  419  GQARTQFRLRDWGISRQRYWGCPIPIIHCEACGDVPVPADQlpvvlpedvvpdGSG---S  475
            G+    +RLRDW +SRQRYWG PIPIIH E     +VP  +LP+VLP       SG   S
Sbjct  406  GNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGES  465

Query  476  PLAKMPEFYECNCPKCGQPAKRETDTMDTFVESSWYFARYACPQFEGGMLDRKAADYWLP  535
            PLA++ +  E      G  ++RET+TM     SSWY+ RY  P+    + D      WLP
Sbjct  466  PLANVTDWLEVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLP  524

Query  536  VDQYIGGIEHAILHLLYARFFHKLMRDEGLVGSDEPFKNLLTQGMVVADTYYRTTANGGK  595
            VD Y+GG EHA+LHLLYARF HK++ D G+V + EPF++L+ QGM+++ + YR       
Sbjct  525  VDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS-YR-------  576

Query  596  DWFNPADVEVERDAKAKVVGARLKSDGQPVEIGGTEKMSKSKNNGVDPQSMIDQYGADTC  655
               ++ +  V  D   K  G+ +  +       +  KMSKS +N V+P+ +++QYGADT 
Sbjct  577  ---DSRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTL  633

Query  656  RLFMMFASPPDMSLEWSDAGVEGANRFLRRVWRLAHA-HVSAGLPGALDVAALSDAQKQV  714
            R++ MF +P D S+ WS+ G+EG+ +FL RV RL  + +++   +GALD           
Sbjct  634  RVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALD-----------  682

Query  715  RRAIHLAIRQASQDVGQHHKFNTAIAAVMTLMNVLEKAPNQDAQDRALIQEGLETVVLLL  774
             +  + +++  +++V ++ KFNTAIA +M ++N  +K       +  L+ +     V L+
Sbjct  683  -KVYNETVKAVTEQV-DQMKFNTAIAQLMVFVNAANK-------EDKLFSDYAKGFVQLI  733

Query  775  APITPHICHVLWGQLGHAEAVID-ARWPSVDESAlvqdtlqlvvqvNGKLRGHIDVAASA  833
            AP++PH+ + LW  L  +   I    WPS DES LV++ +++VVQ++GK+++ + VA   
Sbjct  734  APFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDL  793

Query  834  SREDVEAAARANENVLRFTEGLSIRKVIVVPGKLVNIVAN  873
            SRE+++  A ANE+V     G  I KVI VP KLVNIV +
Sbjct  794  SREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

1646) leuS in NC_021577


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  489 bits (1842),  Expect = 5e-139, Method: Compositional matrix adjust.
 Identities = 359/880 (41%), Positives = 541/880 (62%), Gaps = 61/880 (6%)

Query  5    YQPLEIETQAQNYWKEHQSFLVRELPDKEKFYCLSMFPYPSGK-LHMGHVRNYTIGDVIS  63
            Y+   IE + Q +W ++++F     + K KFY L MFPYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYHRMQGRNVLQPMGWDAFGMPAENAAMKNNVAPAAWTYDNIAYMKSQLDSLGLAIDWSR  123
            R+ R QG+NVL+PMGWDAFG+PAE+ AM     PA  T +NIA  K Q+++LG++ DW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVTTCKPDYYRWEQWLFTRLFEKGVIYRKNGTVNWDPVDQTVLANEQVI-DGRGWRSGAL  182
            EV T  P+YY+W QW+FT+L+EKG+ Y  +  VNW     T +ANE+V+ DG + R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  IEKREIPMYYFKITAYAEELLESLDNLPGWPEQVKTMQRNWIGKSRGMEIGFPYDQASIG  242
            + ++ +    +KITAYAE LLE L+++ +WPE +K MQRNWIGKS G ++ F   ++   
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTD--  240

Query  243  HAGQLKVFTTRPDTLMGATYVAVAAEHPLATQAAQNDPQLQAFIDECKRGGVAEADIA--  300
               ++ VFTTRPDTL GATY  +A+EH+L    + +D Q +A + + KR +   +D+A  
Sbjct  241  --KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSD-QAEA-VADYKRQASLKSDLART  296

Query  301  --TQEKKGMATSLFVEHPLTGDKLPVWVANYVLMNYGEGAVMAVPGHDERDFEFANKYGL  358
              ++EK G+ T+ +  +P+ G  +PVW+A+YVL +YG GA+MAVP+HDERD EFA+++ L
Sbjct  297  DLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNL  356

Query  359  PIRQVIAKVEGDNDFESSVWKEWYGAKDESVLTVNSGKYDNLGYQAAFDAIGADLEAKGL  418
             I  V+   + ++           +A  E  L +NS+  D L+  +A+  +   LEA G+
Sbjct  357  DIIPVLEGGNVEE-----------AAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGV  405

Query  419  GQARTQFRLRDWGISRQRYWGCPIPIIHCEACGDVPVPADQlpvvlpedvvpdGSG---S  475
            G+    +RLRDW +SRQRYWG PIPIIH E     +VP  +LP+VLP       SG   S
Sbjct  406  GNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGES  465

Query  476  PLAKMPEFYECNCPKCGQPAKRETDTMDTFVESSWYFARYACPQFEGGMLDRKAADYWLP  535
            PLA++ +  E      G  ++RET+TM     SSWY+ RY  P+    + D      WLP
Sbjct  466  PLANVTDWLEVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLP  524

Query  536  VDQYIGGIEHAILHLLYARFFHKLMRDEGLVGSDEPFKNLLTQGMVVADTYYRTTANGGK  595
            VD Y+GG EHA+LHLLYARF HK++ D G+V + EPF++L+ QGM+++ + YR       
Sbjct  525  VDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS-YR-------  576

Query  596  DWFNPADVEVERDAKAKVVGARLKSDGQPVEIGGTEKMSKSKNNGVDPQSMIDQYGADTC  655
               ++ +  V  D   K  G+ +  +       +  KMSKS +N V+P+ +++QYGADT 
Sbjct  577  ---DSRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTL  633

Query  656  RLFMMFASPPDMSLEWSDAGVEGANRFLRRVWRLAHA-HVSAGLPGALDVAALSDAQKQV  714
            R++ MF +P D S+ WS+ G+EG+ +FL RV RL  + +++   +GALD           
Sbjct  634  RVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALD-----------  682

Query  715  RRAIHLAIRQASQDVGQHHKFNTAIAAVMTLMNVLEKAPNQDAQDRALIQEGLETVVLLL  774
             +  + +++  +++V ++ KFNTAIA +M ++N  +K       +  L+ +     V L+
Sbjct  683  -KVYNETVKAVTEQV-DQMKFNTAIAQLMVFVNAANK-------EDKLFSDYAKGFVQLI  733

Query  775  APITPHICHVLWGQLGHAEAVID-ARWPSVDESAlvqdtlqlvvqvNGKLRGHIDVAASA  833
            AP++PH+ + LW  L  +   I    WPS DES LV++ +++VVQ++GK+++ + VA   
Sbjct  734  APFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDL  793

Query  834  SREDVEAAARANENVLRFTEGLSIRKVIVVPGKLVNIVAN  873
            SRE+++  A ANE+V     G  I KVI VP KLVNIV +
Sbjct  794  SREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

1647) BIF_00793 in NC_017214


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  489 bits (1842),  Expect = 6e-139, Method: Compositional matrix adjust.
 Identities = 332/752 (45%), Positives = 481/752 (64%), Gaps = 71/752 (9%)

Query  239  LAYISKSPVNWCPGLGTVLANEEVTAEGRSERGNFPVFQRELRQWSMRITAYGHRLIEDL  298
            LAY +  PVNW   LGT +ANEEV ++G SERG +PV ++ +RQW ++ITAY++RL+EDL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  299  DSIDWPEKVKLMQRNWIGESHGASVHFKVPVDGEMADMEIYTTRPDTLFGATFCVVSPEH  358
            + +DWPE +K MQRNWIG S GA+V FKV   +   D  ++TTRPDTLFGAT+ V++PEH
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDK--DFTVFTTRPDTLFGATYAVLAPEH  265

Query  359  PMLEHVPQSWPEGVDPAWTGGYATPSEAVSAYRELAEAKTAADRVADNGEKTGLFTGLYA  418
            ++++ +  S                +EAV+ Y+  A  K+   R     EKTG+ TG YA
Sbjct  266  ALVDAITTS--------------DQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYA  311

Query  419  INPITGAKLPVFTADYVLMDYGTGAIMAVPGGDQRDYDFAVKYGLPVIYTVAPLPDSGDD  478
            INP+ G  +PV  ADYVL  YGTGAIMAVP+ D+RD +FA ++ L +I    P+ ++G+ 
Sbjct  312  INPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDII----PVLEGGN-  366

Query  479  LANYEGTAPFVSHDGIVINSAVDATWARGDALCLDGMRVDDAIAAVTTWLEEAQVGKGAT  538
                   A+F ++DG+ INS             LDG+    AIA +  WLE   VG+   
Sbjct  367  ----VEEAAF-TEDGLHINSD-----------FLDGLDKASAIAKMVEWLEAEGVGNENV  410

Query  539  SYRLRDWLFSRQRYWGEPFPIVYDEHEVPHLVPDSMLPINLPDVPDYSPKTFDPEDSQSS  598
            +YRLRDWLFSRQRYWGEP+PI+  E+  +  VP+S LP+ LP   D  P         ++
Sbjct  411  TYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPS--------GT  462

Query  599  PEAPLSRNEDWVNVTLDLGDGPKTYHHDTNTMPNWAGSCWYYMRYLNPHDTEHMVERDEY  658
             E+PL+   DW++VT +  DG K  +++TNTMP+WAGS WYY+RY++PH+TE + + +  
Sbjct  463  GESPLANVTDWLEVTRE--DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELL  519

Query  659  DYWMGPKHSPAAGQAGGVDLYVGGVEHAVLHLLYSRFWHKILFDLGYVDSFEPFHKLFNQ  718
              W+             VD+YVGG EHAVLHLLY+RFWHK+L+DLG V + EPF+KLFNQ
Sbjct  520  KQWL------------PVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQ  567

Query  719  GMIQAYAYTDDRGQYVPAEDVQESEVDGKTVYTYEGEPVNREFGKMGKSLKNIVTPDYMY  778
            GMI + +Y D RG  V+++ V+    DG       GE +++  +KM+KSLKN+V PD + 
Sbjct  568  GMILGTSYRDSRGALVATDKVEKR--DGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVV  625

Query  779  DHYGADTFRLYEMSMGPLDESRPWNTRNVVGGMRFLQRLWRNVIDENTGEVTVTDDAMDE  838
            ++YGADT+R+YEM MGPLD S +W+   + G+ +FL+R+ R +   +  E     +A+D 
Sbjct  626  EQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITE--ENSGALD-  682

Query  839  RTLKLLNNTIAEVTGEMEAMRPNTAIAKLIVLNNHLTGMNGVPRAAVEPLVLMVAPIAPH  898
               K+ N+T+  VT +++ M+ NTAIA+L+V+ N     + +       +V ++AP+APH
Sbjct  683  ---KVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPH  739

Query  899  IAEELWNRL-GHDESLAHHPWPQADERYVGQDTVTAVVQIKGKVRAKLEVSADIDPDELE  957
            ++EELW+ L + +ES++  PWP  DE  + ++ V  VVQIKGKV+AKL V+ D+  +EL+
Sbjct  740  LGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQ  799

Query  958  KMAL--EAVAERLGGKPPRKVIVKAPKIVSIV  987
             +AL  E V   ++GK   KVI  + K+V+IV
Sbjct  800  EVALANEKVQAEIAGKDIIKVIAVPNKLVNIV  831


 Score =  137 bits (505),  Expect = 3e-33, Method: Compositional matrix adjust.
 Identities = 76/149 (52%), Positives = 105/149 (71%), Gaps = 12/149 (8%)

Query  32   IEEKWQDIWESEGTFWAANVSGELTDSKGRHADGRQSFFAMDMFPYPSGKGLHVGHPLGY  91
            IE KWQ +W  + TF            K     ++  F+A+DMFPYPSG GLHVGHP GY
Sbjct  9    IEPKWQAFWADNHTF------------KTGTDASKPKFYALDMFPYPSGAGLHVGHPEGY  56

Query  92   LATDVVSRYHRMKGENVLHAMGYDAFGLPAEQYAVQTGQHPRITTEQNIANMRRQLRRMG  151
             ATD++SR+ R +G+NVLH+MG DAFGLPAEQYA++TG++P   T +NIAN +RQ+  +G
Sbjct  57   TATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALG  116

Query  152  LSFDDRRSFATIEPEYVRWTQWIFSRIYD  180
            +S+D  R   T +P+Y +WTQWIF+++Y+
Sbjct  117  FSYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1648) BALAC2494_00374 in NC_017215


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  489 bits (1842),  Expect = 6e-139, Method: Compositional matrix adjust.
 Identities = 332/752 (45%), Positives = 481/752 (64%), Gaps = 71/752 (9%)

Query  239  LAYISKSPVNWCPGLGTVLANEEVTAEGRSERGNFPVFQRELRQWSMRITAYGHRLIEDL  298
            LAY +  PVNW   LGT +ANEEV ++G SERG +PV ++ +RQW ++ITAY++RL+EDL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  299  DSIDWPEKVKLMQRNWIGESHGASVHFKVPVDGEMADMEIYTTRPDTLFGATFCVVSPEH  358
            + +DWPE +K MQRNWIG S GA+V FKV   +   D  ++TTRPDTLFGAT+ V++PEH
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDK--DFTVFTTRPDTLFGATYAVLAPEH  265

Query  359  PMLEHVPQSWPEGVDPAWTGGYATPSEAVSAYRELAEAKTAADRVADNGEKTGLFTGLYA  418
            ++++ +  S                +EAV+ Y+  A  K+   R     EKTG+ TG YA
Sbjct  266  ALVDAITTS--------------DQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYA  311

Query  419  INPITGAKLPVFTADYVLMDYGTGAIMAVPGGDQRDYDFAVKYGLPVIYTVAPLPDSGDD  478
            INP+ G  +PV  ADYVL  YGTGAIMAVP+ D+RD +FA ++ L +I    P+ ++G+ 
Sbjct  312  INPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDII----PVLEGGN-  366

Query  479  LANYEGTAPFVSHDGIVINSAVDATWARGDALCLDGMRVDDAIAAVTTWLEEAQVGKGAT  538
                   A+F ++DG+ INS             LDG+    AIA +  WLE   VG+   
Sbjct  367  ----VEEAAF-TEDGLHINSD-----------FLDGLDKASAIAKMVEWLEAEGVGNENV  410

Query  539  SYRLRDWLFSRQRYWGEPFPIVYDEHEVPHLVPDSMLPINLPDVPDYSPKTFDPEDSQSS  598
            +YRLRDWLFSRQRYWGEP+PI+  E+  +  VP+S LP+ LP   D  P         ++
Sbjct  411  TYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPS--------GT  462

Query  599  PEAPLSRNEDWVNVTLDLGDGPKTYHHDTNTMPNWAGSCWYYMRYLNPHDTEHMVERDEY  658
             E+PL+   DW++VT +  DG K  +++TNTMP+WAGS WYY+RY++PH+TE + + +  
Sbjct  463  GESPLANVTDWLEVTRE--DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELL  519

Query  659  DYWMGPKHSPAAGQAGGVDLYVGGVEHAVLHLLYSRFWHKILFDLGYVDSFEPFHKLFNQ  718
              W+             VD+YVGG EHAVLHLLY+RFWHK+L+DLG V + EPF+KLFNQ
Sbjct  520  KQWL------------PVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQ  567

Query  719  GMIQAYAYTDDRGQYVPAEDVQESEVDGKTVYTYEGEPVNREFGKMGKSLKNIVTPDYMY  778
            GMI + +Y D RG  V+++ V+    DG       GE +++  +KM+KSLKN+V PD + 
Sbjct  568  GMILGTSYRDSRGALVATDKVEKR--DGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVV  625

Query  779  DHYGADTFRLYEMSMGPLDESRPWNTRNVVGGMRFLQRLWRNVIDENTGEVTVTDDAMDE  838
            ++YGADT+R+YEM MGPLD S +W+   + G+ +FL+R+ R +   +  E     +A+D 
Sbjct  626  EQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITE--ENSGALD-  682

Query  839  RTLKLLNNTIAEVTGEMEAMRPNTAIAKLIVLNNHLTGMNGVPRAAVEPLVLMVAPIAPH  898
               K+ N+T+  VT +++ M+ NTAIA+L+V+ N     + +       +V ++AP+APH
Sbjct  683  ---KVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPH  739

Query  899  IAEELWNRL-GHDESLAHHPWPQADERYVGQDTVTAVVQIKGKVRAKLEVSADIDPDELE  957
            ++EELW+ L + +ES++  PWP  DE  + ++ V  VVQIKGKV+AKL V+ D+  +EL+
Sbjct  740  LGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQ  799

Query  958  KMAL--EAVAERLGGKPPRKVIVKAPKIVSIV  987
             +AL  E V   ++GK   KVI  + K+V+IV
Sbjct  800  EVALANEKVQAEIAGKDIIKVIAVPNKLVNIV  831


 Score =  137 bits (505),  Expect = 3e-33, Method: Compositional matrix adjust.
 Identities = 76/149 (52%), Positives = 105/149 (71%), Gaps = 12/149 (8%)

Query  32   IEEKWQDIWESEGTFWAANVSGELTDSKGRHADGRQSFFAMDMFPYPSGKGLHVGHPLGY  91
            IE KWQ +W  + TF            K     ++  F+A+DMFPYPSG GLHVGHP GY
Sbjct  9    IEPKWQAFWADNHTF------------KTGTDASKPKFYALDMFPYPSGAGLHVGHPEGY  56

Query  92   LATDVVSRYHRMKGENVLHAMGYDAFGLPAEQYAVQTGQHPRITTEQNIANMRRQLRRMG  151
             ATD++SR+ R +G+NVLH+MG DAFGLPAEQYA++TG++P   T +NIAN +RQ+  +G
Sbjct  57   TATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALG  116

Query  152  LSFDDRRSFATIEPEYVRWTQWIFSRIYD  180
            +S+D  R   T +P+Y +WTQWIF+++Y+
Sbjct  117  FSYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1649) leuS in NC_018150


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  488 bits (1841),  Expect = 6e-139, Method: Compositional matrix adjust.
 Identities = 343/739 (47%), Positives = 497/739 (68%), Gaps = 65/739 (8%)

Query  224  LVYQSDSVVNWCPGLGTVLANEEVTADGRSERGNFPVFRKRLRQWMMRITAYSDRLIDDL  283
            L Y+++  VNW   LGT +ANEEV +DG SERG +PV RK +RQWM++ITAY++RL++DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  284  DVLDWPDKVKTMQRNWIGRSQGASVLFGAPGVG-DIEVFTTRPDTLFGATYMVLAPEHPL  342
            + +DWP+ +K MQRNWIG+S GA+V F   + + D+ VFTTRPDTLFGATY VLAPEH+L
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  343  VDQLAADVWPQDTDPRWTGGQDSPRAAIEQYRRSIAAKSDLERQE-NKEKTGVFTGAYAT  401
            VD +++                    A+ +Y+R  + KSDL R +  KEKTGV TG+YA 
Sbjct  268  VDAITTS---------------DQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAI  312

Query  402  NPVSGKPVPVFIADYVLLGYGTGAIMAVPGHDQRDWDFANTFGLPVQEVISGGDVTEAAY  461
            NPV+GK +PV IADYVL +YGTGAIMAVP+HD+RDW+FA+ F L +  V+ GG+V EAA+
Sbjct  313  NPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEAAF  372

Query  462  TGDGALVNSDYLDGLDIEAAKVEVTRRLVKDGRGESRIEYKLRDWLFARQRYWGEPFPIV  521
            T DG  +NSD+LDGLD  +A   +  +L  +G G+  + Y+LRDWLF+RQRYWGEP+PI+
Sbjct  373  TEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPII  432

Query  522  YDEDGRPRALGedvlpvelpevedYAPVsfdpddassepspplsKAADWVNVELDLGDGL  581
              EDG + A+ E  LP+ LP   D  P        S+   +PL++ +DW++V  +  DG+
Sbjct  433  HWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTDWLEVTRE--DGV  482

Query  582  KHYTRDTNVMPQWAGSSWYELRYADPDNAEAFCDKENEAYWLGPRPAEHGPNDPGGVDLY  641
            K   R+TN MPQWAGSSWY LRY DP+N+E + D E    WL              VD+Y
Sbjct  483  KG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWL-------------PVDIY  528

Query  642  VGGMEHAVLHLLYSRFWHKVLYDLGHVSSREPYRRLLNQGYIQAHAYTDARGMYVPAAEV  701
            VGG EHAVLHLLY+RFWHKVLYDLG V+++EP+++L+NQG I + +Y D+RG  V++  V
Sbjct  529  VGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKV  588

Query  702  TEENGRFFY--RGAEVQQEFGKIGKSLKNSISPDDICDNYGADTLRVYEMSMGPLELSRP  759
               +G FF    G E++Q  +K++KSLKN ++PDD+ ++YGADTLRVYEM MGPL+ S +
Sbjct  589  EKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIA  648

Query  760  WATKDVVGAHRFLQRAWRVVVDEETGKIRVTTDDLTSEDTLRALHKTIAGVTEDYAALRN  819
            W+  ++ G+++FL+R  R++   E     +T ++  + D  +  + T+ +VTE+   ++ 
Sbjct  649  WSEEGLEGSRKFLDRVYRLITTKE-----ITEENSGALD--KVYNETVKAVTEQVDQMKF  701

Query  820  NTAAAKLIEYTNHLTKE------YPEGAPRaaveplvlmlaplaphlaeelW-SLLGRDD  872
            NTA A+L+ + N   KE      Y+ G  +        ++AP+APHL+EELW +L + ++
Sbjct  702  NTAIAQLMVFVNAANKEDKLFSDYAKGFVQ--------LIAPFAPHLGEELWQALTASGE  753

Query  873  SLAHGPFPESDDRWLVADTVEYPIQVNGKVRGRITVAADAPKGDIEAAALTEEKVLEFLA  932
            S++  P P  D+  LV + VE  +Q++GKV++++ VA D ++ +++  AL++EKV   +A
Sbjct  754  SISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIA  813

Query  933  GATPKKVIVVPGRMVNLVV  951
            G    KVI VP ++VN+V+
Sbjct  814  GKDIIKVIAVPNKLVNIVI  832


 Score =  132 bits (486),  Expect = 8e-32, Method: Compositional matrix adjust.
 Identities = 78/148 (53%), Positives = 98/148 (67%), Gaps = 11/148 (7%)

Query  27   IERRWQQTWADRGTFHVPNPVGSLAPTDGTPIPADKMFVQDMFPYPSGDGLHVGHPLGYI  86
            IE +WQ  WAD  TF             GT  +  K +  DMFPYPSG GLHVGHP GY 
Sbjct  9    IEPKWQAFWADNHTFKT-----------GTDASKPKFYALDMFPYPSGAGLHVGHPEGYT  57

Query  87   ATDVYARFHRMRGANVLHALGFDAFGLPAEQYAVQTGTHPRVRTEANIVNYKRQLGRLGL  146
            ATD+ +RF R +G NVLH++G DAFGLPAEQYA++TG +P   T  NI N+KRQ+  LG+
Sbjct  58   ATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGF  117

Query  147  GHDSRRSFATTDVDFYKWTQWIFLQIYN  174
            + D  R   TTD ++YKWTQWIF ++Y+
Sbjct  118  SYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1650) Echvi_2126 in NC_019904


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  488 bits (1841),  Expect = 6e-139, Method: Compositional matrix adjust.
 Identities = 326/723 (46%), Positives = 470/723 (66%), Gaps = 50/723 (6%)

Query  210  AETTVNWCAALGTVLSNDEV-KDGFSERGGHPVERKKMMQWSMRITAYAERLLNDLEKVD  268
            AE  VNW   LGT ++N+EV  DG SERGG PV RK M QW ++ITAYAERLL+DLE VD
Sbjct  152  AEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDLEEVD  211

Query  269  WPEPIKEMQRNWIGRSVGAEMIFQVKDRPQQIKVFTTRIDTIYGVTYLALAPESDLAAEL  328
            WPE+IK+MQRNWIG+S GA++ F+VKD  +++ VFTTR DT++G TY  LAPE  L   +
Sbjct  212  WPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHALVDAI  271

Query  329  ITDDQREEAEAYIQVAKNRSERDRMSDVKTISGAFTGSYAINPFNGEEIPVWIADYVLAG  388
             T DQ E    Y + A  +S+  R    K  +G  TGSYAINP NG E+PVWIADYVLA+
Sbjct  272  TTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLAS  331

Query  389  YGTGAVMAVPAHDERDYNFANHFGLEVRQVLEGS-MENGSFPGRDGIAMNSGFLDGLVMK  447
            YGTGA+MAVPAHDERD +FA++F L++  VLEG+ +E+++F   DG+ +NS+FLDGL   
Sbjct  332  YGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEAAFTE-DGLHINSDFLDGLDKA  390

Query  448  DAMEKAIAFLEEKNIGKGKIQYRMRDAIFTRQRYWGEPLP-VYFDDGIPYLVDEKDLPIV  506
             A+ K +  LE   +G+ ++ YR+RD +F+RQRYWGEP+P +  +DG +  V E +LP+V
Sbjct  391  SAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLV  450

Query  507  LPEVDKYLPTEDGEPPLGRATDW--TYQVNGKDYPLELSTMPGWAGSSWYFLRYMDPQNN  564
            LP      P+  GE+PL+  TDW    + +G     E +TMP WAGSSWY+LRY+DP+N 
Sbjct  451  LPVTKDIRPSGTGESPLANVTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNT  510

Query  565  TELVSKDAQQYWEAVDLYIGGAEHATGHLLYSRFWTKFLYDKGLINIVEPFKKMINQGMI  624
              L   +  + W +VD+Y+GGAEHA  HLLY+RFW K LYD G++   EPF+K++NQGMI
Sbjct  511  EKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMI  570

Query  625  QGRSNFVYRIKGTNTFVSHGLRKDHDTAAMHVDVNIVHNDQLDLDKFKAWRPDLADAEFI  684
             G S   YR  +  ++V+ +    +D +  HV+      ++L+                 
Sbjct  571  LGTS---YR-DSRGALVATDKVEKRDGSFFHVET----GEELE-----------------  605

Query  685  LEDGKYLCGAEVEKMSKSKYNVVNPDDIIERYGADTLRLYEMFLGPLEQFKPWNTNGIDG  744
                         KMSKS  NVVNPDD++E+YGADTLR+YEMF+GPL+   +W+ +G++G
Sbjct  606  ---------QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEG  656

Query  745  VSKFLKKLWRLFHDKNGNFSISNANPTKEELKTLHKTIKKAEEDMNNYSFNTSVSSFMIC  804
              KFL ++ RL+  K+    I++ N+   + K  + T+K   E++++  FNT+++ +M+ 
Sbjct  657  SRKFLDRVYRLITTKE----ITEENSGALD-KVYNETVKAVTEQVDQMKFNTAIAQLMVF  711

Query  805  VNELSALKCNK--RDILEPLTIIISPYAPHIAEELW-SLLGHDRSVLEARFPQFNEEFLT  861
            VN  +A K +K   D    +  +I+P+APH++EELW +L + + S+     P ++E  L 
Sbjct  712  VN--AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLV  769

Query  862  EDAHEYPISINGKMRVKLPISLSLSKEEIEKTALADANVQKWLDGKTPKKIIVVPGKIVN  921
            E+  E  + I+GK++ KL ++  LS+EE++  ALA+ +VQ  + GK   K+I VP K+VN
Sbjct  770  ENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVN  829

Query  922  IVV  924
            IV+
Sbjct  830  IVI  832


 Score =  178 bits (659),  Expect = 2e-45, Method: Compositional matrix adjust.
 Identities = 87/142 (62%), Positives = 116/142 (82%), Gaps = 0/142 (0%)

Query  4    YNFQEIEKKWQERWETSQVFNAKIDPQRPKFYSLDMFPYPSGAGLHVGHPLGYIASDIVT  63
            Y+   IE KWQ  W  ++ F++  D+ +PKFY+LDMFPYPSGAGLHVGHP GY A+DI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RFKRLQGYNVLHPMGYDSFGLPAEQYAIQTGQHPAITTEQNIARYTEQLKNIGFAFDWDK  123
            RFKR QG NVLHPMG D+FGLPAEQYA++TG++PA  T +NIA +  Q++ +GF++DWD+
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVRTSDPSYYKWTQWIFMQLFD  145
            EV T+DP+YYKWTQWIF +L++
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYE  145

1651) leuS in NC_011835


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  488 bits (1841),  Expect = 6e-139, Method: Compositional matrix adjust.
 Identities = 332/752 (45%), Positives = 481/752 (64%), Gaps = 71/752 (9%)

Query  237  LAYISKSPVNWCPGLGTVLANEEVTAEGRSERGNFPVFQRELRQWSMRITAYGHRLIEDL  296
            LAY +  PVNW   LGT +ANEEV ++G SERG +PV ++ +RQW ++ITAY++RL+EDL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  297  DSIDWPEKVKLMQRNWIGESHGASVHFKVPVDGEMADMEIYTTRPDTLFGATFCVVSPEH  356
            + +DWPE +K MQRNWIG S GA+V FKV   +   D  ++TTRPDTLFGAT+ V++PEH
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDK--DFTVFTTRPDTLFGATYAVLAPEH  265

Query  357  PMLEHVPQSWPEGVDPAWTGGYATPSEAVSAYRELAEAKTAADRVADNGEKTGLFTGLYA  416
            ++++ +  S                +EAV+ Y+  A  K+   R     EKTG+ TG YA
Sbjct  266  ALVDAITTS--------------DQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYA  311

Query  417  INPITGAKLPVFTADYVLMDYGTGAIMAVPGGDQRDYDFAVKYGLPVIYTVAPLPDSGDD  476
            INP+ G  +PV  ADYVL  YGTGAIMAVP+ D+RD +FA ++ L +I    P+ ++G+ 
Sbjct  312  INPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDII----PVLEGGN-  366

Query  477  LANYEGTAPFVSHDGIVINSAVDATWARGDALCLDGMRVDDAIAAVTTWLEEAQVGKGAT  536
                   A+F ++DG+ INS             LDG+    AIA +  WLE   VG+   
Sbjct  367  ----VEEAAF-TEDGLHINSD-----------FLDGLDKASAIAKMVEWLEAEGVGNENV  410

Query  537  SYRLRDWLFSRQRYWGEPFPIVYDEHEVPHLVPDSMLPINLPDVPDYSPKTFDPEDSQSS  596
            +YRLRDWLFSRQRYWGEP+PI+  E+  +  VP+S LP+ LP   D  P         ++
Sbjct  411  TYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPS--------GT  462

Query  597  PEAPLSRNEDWVNVTLDLGDGPKTYHHDTNTMPNWAGSCWYYMRYLNPHDTEHMVERDEY  656
             E+PL+   DW++VT +  DG K  +++TNTMP+WAGS WYY+RY++PH+TE + + +  
Sbjct  463  GESPLANVTDWLEVTRE--DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELL  519

Query  657  DYWMGPKHSPAAGQAGGVDLYVGGVEHAVLHLLYSRFWHKILFDLGYVDSFEPFHKLFNQ  716
              W+             VD+YVGG EHAVLHLLY+RFWHK+L+DLG V + EPF+KLFNQ
Sbjct  520  KQWL------------PVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQ  567

Query  717  GMIQAYAYTDDRGQYVPAEDVQESEVDGKTVYTYEGEPVNREFGKMGKSLKNIVTPDYMY  776
            GMI + +Y D RG  V+++ V+    DG       GE +++  +KM+KSLKN+V PD + 
Sbjct  568  GMILGTSYRDSRGALVATDKVEKR--DGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVV  625

Query  777  DHYGADTFRLYEMSMGPLDESRPWNTRNVVGGMRFLQRLWRNVIDENTGEVTVTDDAMDE  836
            ++YGADT+R+YEM MGPLD S +W+   + G+ +FL+R+ R +   +  E     +A+D 
Sbjct  626  EQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITE--ENSGALD-  682

Query  837  RTLKLLNNTIAEVTGEMEAMRPNTAIAKLIVLNNHLTGMNGVPRAAVEPLVLMVAPIAPH  896
               K+ N+T+  VT +++ M+ NTAIA+L+V+ N     + +       +V ++AP+APH
Sbjct  683  ---KVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPH  739

Query  897  IAEELWNRL-GHDESLAHHPWPQADERYVGQDTVTAVVQIKGKVRAKLEVSADIDPDELE  955
            ++EELW+ L + +ES++  PWP  DE  + ++ V  VVQIKGKV+AKL V+ D+  +EL+
Sbjct  740  LGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQ  799

Query  956  KMAL--EAVAERLGGKPPRKVIVKAPKIVSIV  985
             +AL  E V   ++GK   KVI  + K+V+IV
Sbjct  800  EVALANEKVQAEIAGKDIIKVIAVPNKLVNIV  831


 Score =  137 bits (505),  Expect = 3e-33, Method: Compositional matrix adjust.
 Identities = 76/149 (52%), Positives = 105/149 (71%), Gaps = 12/149 (8%)

Query  30   IEEKWQDIWESEGTFWAANVSGELTDSKGRHADGRQSFFAMDMFPYPSGKGLHVGHPLGY  89
            IE KWQ +W  + TF            K     ++  F+A+DMFPYPSG GLHVGHP GY
Sbjct  9    IEPKWQAFWADNHTF------------KTGTDASKPKFYALDMFPYPSGAGLHVGHPEGY  56

Query  90   LATDVVSRYHRMKGENVLHAMGYDAFGLPAEQYAVQTGQHPRITTEQNIANMRRQLRRMG  149
             ATD++SR+ R +G+NVLH+MG DAFGLPAEQYA++TG++P   T +NIAN +RQ+  +G
Sbjct  57   TATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALG  116

Query  150  LSFDDRRSFATIEPEYVRWTQWIFSRIYD  178
            +S+D  R   T +P+Y +WTQWIF+++Y+
Sbjct  117  FSYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1652) W7Y_0757 in NC_017866


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  488 bits (1841),  Expect = 6e-139, Method: Compositional matrix adjust.
 Identities = 332/752 (45%), Positives = 481/752 (64%), Gaps = 71/752 (9%)

Query  237  LAYISKSPVNWCPGLGTVLANEEVTAEGRSERGNFPVFQRELRQWSMRITAYGHRLIEDL  296
            LAY +  PVNW   LGT +ANEEV ++G SERG +PV ++ +RQW ++ITAY++RL+EDL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  297  DSIDWPEKVKLMQRNWIGESHGASVHFKVPVDGEMADMEIYTTRPDTLFGATFCVVSPEH  356
            + +DWPE +K MQRNWIG S GA+V FKV   +   D  ++TTRPDTLFGAT+ V++PEH
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDK--DFTVFTTRPDTLFGATYAVLAPEH  265

Query  357  PMLEHVPQSWPEGVDPAWTGGYATPSEAVSAYRELAEAKTAADRVADNGEKTGLFTGLYA  416
            ++++ +  S                +EAV+ Y+  A  K+   R     EKTG+ TG YA
Sbjct  266  ALVDAITTS--------------DQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYA  311

Query  417  INPITGAKLPVFTADYVLMDYGTGAIMAVPGGDQRDYDFAVKYGLPVIYTVAPLPDSGDD  476
            INP+ G  +PV  ADYVL  YGTGAIMAVP+ D+RD +FA ++ L +I    P+ ++G+ 
Sbjct  312  INPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDII----PVLEGGN-  366

Query  477  LANYEGTAPFVSHDGIVINSAVDATWARGDALCLDGMRVDDAIAAVTTWLEEAQVGKGAT  536
                   A+F ++DG+ INS             LDG+    AIA +  WLE   VG+   
Sbjct  367  ----VEEAAF-TEDGLHINSD-----------FLDGLDKASAIAKMVEWLEAEGVGNENV  410

Query  537  SYRLRDWLFSRQRYWGEPFPIVYDEHEVPHLVPDSMLPINLPDVPDYSPKTFDPEDSQSS  596
            +YRLRDWLFSRQRYWGEP+PI+  E+  +  VP+S LP+ LP   D  P         ++
Sbjct  411  TYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPS--------GT  462

Query  597  PEAPLSRNEDWVNVTLDLGDGPKTYHHDTNTMPNWAGSCWYYMRYLNPHDTEHMVERDEY  656
             E+PL+   DW++VT +  DG K  +++TNTMP+WAGS WYY+RY++PH+TE + + +  
Sbjct  463  GESPLANVTDWLEVTRE--DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELL  519

Query  657  DYWMGPKHSPAAGQAGGVDLYVGGVEHAVLHLLYSRFWHKILFDLGYVDSFEPFHKLFNQ  716
              W+             VD+YVGG EHAVLHLLY+RFWHK+L+DLG V + EPF+KLFNQ
Sbjct  520  KQWL------------PVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQ  567

Query  717  GMIQAYAYTDDRGQYVPAEDVQESEVDGKTVYTYEGEPVNREFGKMGKSLKNIVTPDYMY  776
            GMI + +Y D RG  V+++ V+    DG       GE +++  +KM+KSLKN+V PD + 
Sbjct  568  GMILGTSYRDSRGALVATDKVEKR--DGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVV  625

Query  777  DHYGADTFRLYEMSMGPLDESRPWNTRNVVGGMRFLQRLWRNVIDENTGEVTVTDDAMDE  836
            ++YGADT+R+YEM MGPLD S +W+   + G+ +FL+R+ R +   +  E     +A+D 
Sbjct  626  EQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITE--ENSGALD-  682

Query  837  RTLKLLNNTIAEVTGEMEAMRPNTAIAKLIVLNNHLTGMNGVPRAAVEPLVLMVAPIAPH  896
               K+ N+T+  VT +++ M+ NTAIA+L+V+ N     + +       +V ++AP+APH
Sbjct  683  ---KVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPH  739

Query  897  IAEELWNRL-GHDESLAHHPWPQADERYVGQDTVTAVVQIKGKVRAKLEVSADIDPDELE  955
            ++EELW+ L + +ES++  PWP  DE  + ++ V  VVQIKGKV+AKL V+ D+  +EL+
Sbjct  740  LGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQ  799

Query  956  KMAL--EAVAERLGGKPPRKVIVKAPKIVSIV  985
             +AL  E V   ++GK   KVI  + K+V+IV
Sbjct  800  EVALANEKVQAEIAGKDIIKVIAVPNKLVNIV  831


 Score =  137 bits (505),  Expect = 3e-33, Method: Compositional matrix adjust.
 Identities = 76/149 (52%), Positives = 105/149 (71%), Gaps = 12/149 (8%)

Query  30   IEEKWQDIWESEGTFWAANVSGELTDSKGRHADGRQSFFAMDMFPYPSGKGLHVGHPLGY  89
            IE KWQ +W  + TF            K     ++  F+A+DMFPYPSG GLHVGHP GY
Sbjct  9    IEPKWQAFWADNHTF------------KTGTDASKPKFYALDMFPYPSGAGLHVGHPEGY  56

Query  90   LATDVVSRYHRMKGENVLHAMGYDAFGLPAEQYAVQTGQHPRITTEQNIANMRRQLRRMG  149
             ATD++SR+ R +G+NVLH+MG DAFGLPAEQYA++TG++P   T +NIAN +RQ+  +G
Sbjct  57   TATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALG  116

Query  150  LSFDDRRSFATIEPEYVRWTQWIFSRIYD  178
            +S+D  R   T +P+Y +WTQWIF+++Y+
Sbjct  117  FSYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1653) W91_0779 in NC_017867


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  488 bits (1841),  Expect = 6e-139, Method: Compositional matrix adjust.
 Identities = 332/752 (45%), Positives = 481/752 (64%), Gaps = 71/752 (9%)

Query  237  LAYISKSPVNWCPGLGTVLANEEVTAEGRSERGNFPVFQRELRQWSMRITAYGHRLIEDL  296
            LAY +  PVNW   LGT +ANEEV ++G SERG +PV ++ +RQW ++ITAY++RL+EDL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  297  DSIDWPEKVKLMQRNWIGESHGASVHFKVPVDGEMADMEIYTTRPDTLFGATFCVVSPEH  356
            + +DWPE +K MQRNWIG S GA+V FKV   +   D  ++TTRPDTLFGAT+ V++PEH
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDK--DFTVFTTRPDTLFGATYAVLAPEH  265

Query  357  PMLEHVPQSWPEGVDPAWTGGYATPSEAVSAYRELAEAKTAADRVADNGEKTGLFTGLYA  416
            ++++ +  S                +EAV+ Y+  A  K+   R     EKTG+ TG YA
Sbjct  266  ALVDAITTS--------------DQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYA  311

Query  417  INPITGAKLPVFTADYVLMDYGTGAIMAVPGGDQRDYDFAVKYGLPVIYTVAPLPDSGDD  476
            INP+ G  +PV  ADYVL  YGTGAIMAVP+ D+RD +FA ++ L +I    P+ ++G+ 
Sbjct  312  INPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDII----PVLEGGN-  366

Query  477  LANYEGTAPFVSHDGIVINSAVDATWARGDALCLDGMRVDDAIAAVTTWLEEAQVGKGAT  536
                   A+F ++DG+ INS             LDG+    AIA +  WLE   VG+   
Sbjct  367  ----VEEAAF-TEDGLHINSD-----------FLDGLDKASAIAKMVEWLEAEGVGNENV  410

Query  537  SYRLRDWLFSRQRYWGEPFPIVYDEHEVPHLVPDSMLPINLPDVPDYSPKTFDPEDSQSS  596
            +YRLRDWLFSRQRYWGEP+PI+  E+  +  VP+S LP+ LP   D  P         ++
Sbjct  411  TYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPS--------GT  462

Query  597  PEAPLSRNEDWVNVTLDLGDGPKTYHHDTNTMPNWAGSCWYYMRYLNPHDTEHMVERDEY  656
             E+PL+   DW++VT +  DG K  +++TNTMP+WAGS WYY+RY++PH+TE + + +  
Sbjct  463  GESPLANVTDWLEVTRE--DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELL  519

Query  657  DYWMGPKHSPAAGQAGGVDLYVGGVEHAVLHLLYSRFWHKILFDLGYVDSFEPFHKLFNQ  716
              W+             VD+YVGG EHAVLHLLY+RFWHK+L+DLG V + EPF+KLFNQ
Sbjct  520  KQWL------------PVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQ  567

Query  717  GMIQAYAYTDDRGQYVPAEDVQESEVDGKTVYTYEGEPVNREFGKMGKSLKNIVTPDYMY  776
            GMI + +Y D RG  V+++ V+    DG       GE +++  +KM+KSLKN+V PD + 
Sbjct  568  GMILGTSYRDSRGALVATDKVEKR--DGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVV  625

Query  777  DHYGADTFRLYEMSMGPLDESRPWNTRNVVGGMRFLQRLWRNVIDENTGEVTVTDDAMDE  836
            ++YGADT+R+YEM MGPLD S +W+   + G+ +FL+R+ R +   +  E     +A+D 
Sbjct  626  EQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITE--ENSGALD-  682

Query  837  RTLKLLNNTIAEVTGEMEAMRPNTAIAKLIVLNNHLTGMNGVPRAAVEPLVLMVAPIAPH  896
               K+ N+T+  VT +++ M+ NTAIA+L+V+ N     + +       +V ++AP+APH
Sbjct  683  ---KVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPH  739

Query  897  IAEELWNRL-GHDESLAHHPWPQADERYVGQDTVTAVVQIKGKVRAKLEVSADIDPDELE  955
            ++EELW+ L + +ES++  PWP  DE  + ++ V  VVQIKGKV+AKL V+ D+  +EL+
Sbjct  740  LGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQ  799

Query  956  KMAL--EAVAERLGGKPPRKVIVKAPKIVSIV  985
             +AL  E V   ++GK   KVI  + K+V+IV
Sbjct  800  EVALANEKVQAEIAGKDIIKVIAVPNKLVNIV  831


 Score =  137 bits (505),  Expect = 3e-33, Method: Compositional matrix adjust.
 Identities = 76/149 (52%), Positives = 105/149 (71%), Gaps = 12/149 (8%)

Query  30   IEEKWQDIWESEGTFWAANVSGELTDSKGRHADGRQSFFAMDMFPYPSGKGLHVGHPLGY  89
            IE KWQ +W  + TF            K     ++  F+A+DMFPYPSG GLHVGHP GY
Sbjct  9    IEPKWQAFWADNHTF------------KTGTDASKPKFYALDMFPYPSGAGLHVGHPEGY  56

Query  90   LATDVVSRYHRMKGENVLHAMGYDAFGLPAEQYAVQTGQHPRITTEQNIANMRRQLRRMG  149
             ATD++SR+ R +G+NVLH+MG DAFGLPAEQYA++TG++P   T +NIAN +RQ+  +G
Sbjct  57   TATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALG  116

Query  150  LSFDDRRSFATIEPEYVRWTQWIFSRIYD  178
            +S+D  R   T +P+Y +WTQWIF+++Y+
Sbjct  117  FSYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1654) Bl12_0705 in NC_021593


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  488 bits (1841),  Expect = 6e-139, Method: Compositional matrix adjust.
 Identities = 332/752 (45%), Positives = 481/752 (64%), Gaps = 71/752 (9%)

Query  237  LAYISKSPVNWCPGLGTVLANEEVTAEGRSERGNFPVFQRELRQWSMRITAYGHRLIEDL  296
            LAY +  PVNW   LGT +ANEEV ++G SERG +PV ++ +RQW ++ITAY++RL+EDL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  297  DSIDWPEKVKLMQRNWIGESHGASVHFKVPVDGEMADMEIYTTRPDTLFGATFCVVSPEH  356
            + +DWPE +K MQRNWIG S GA+V FKV   +   D  ++TTRPDTLFGAT+ V++PEH
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDK--DFTVFTTRPDTLFGATYAVLAPEH  265

Query  357  PMLEHVPQSWPEGVDPAWTGGYATPSEAVSAYRELAEAKTAADRVADNGEKTGLFTGLYA  416
            ++++ +  S                +EAV+ Y+  A  K+   R     EKTG+ TG YA
Sbjct  266  ALVDAITTS--------------DQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYA  311

Query  417  INPITGAKLPVFTADYVLMDYGTGAIMAVPGGDQRDYDFAVKYGLPVIYTVAPLPDSGDD  476
            INP+ G  +PV  ADYVL  YGTGAIMAVP+ D+RD +FA ++ L +I    P+ ++G+ 
Sbjct  312  INPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDII----PVLEGGN-  366

Query  477  LANYEGTAPFVSHDGIVINSAVDATWARGDALCLDGMRVDDAIAAVTTWLEEAQVGKGAT  536
                   A+F ++DG+ INS             LDG+    AIA +  WLE   VG+   
Sbjct  367  ----VEEAAF-TEDGLHINSD-----------FLDGLDKASAIAKMVEWLEAEGVGNENV  410

Query  537  SYRLRDWLFSRQRYWGEPFPIVYDEHEVPHLVPDSMLPINLPDVPDYSPKTFDPEDSQSS  596
            +YRLRDWLFSRQRYWGEP+PI+  E+  +  VP+S LP+ LP   D  P         ++
Sbjct  411  TYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPS--------GT  462

Query  597  PEAPLSRNEDWVNVTLDLGDGPKTYHHDTNTMPNWAGSCWYYMRYLNPHDTEHMVERDEY  656
             E+PL+   DW++VT +  DG K  +++TNTMP+WAGS WYY+RY++PH+TE + + +  
Sbjct  463  GESPLANVTDWLEVTRE--DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELL  519

Query  657  DYWMGPKHSPAAGQAGGVDLYVGGVEHAVLHLLYSRFWHKILFDLGYVDSFEPFHKLFNQ  716
              W+             VD+YVGG EHAVLHLLY+RFWHK+L+DLG V + EPF+KLFNQ
Sbjct  520  KQWL------------PVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQ  567

Query  717  GMIQAYAYTDDRGQYVPAEDVQESEVDGKTVYTYEGEPVNREFGKMGKSLKNIVTPDYMY  776
            GMI + +Y D RG  V+++ V+    DG       GE +++  +KM+KSLKN+V PD + 
Sbjct  568  GMILGTSYRDSRGALVATDKVEKR--DGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVV  625

Query  777  DHYGADTFRLYEMSMGPLDESRPWNTRNVVGGMRFLQRLWRNVIDENTGEVTVTDDAMDE  836
            ++YGADT+R+YEM MGPLD S +W+   + G+ +FL+R+ R +   +  E     +A+D 
Sbjct  626  EQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITE--ENSGALD-  682

Query  837  RTLKLLNNTIAEVTGEMEAMRPNTAIAKLIVLNNHLTGMNGVPRAAVEPLVLMVAPIAPH  896
               K+ N+T+  VT +++ M+ NTAIA+L+V+ N     + +       +V ++AP+APH
Sbjct  683  ---KVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPH  739

Query  897  IAEELWNRL-GHDESLAHHPWPQADERYVGQDTVTAVVQIKGKVRAKLEVSADIDPDELE  955
            ++EELW+ L + +ES++  PWP  DE  + ++ V  VVQIKGKV+AKL V+ D+  +EL+
Sbjct  740  LGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQ  799

Query  956  KMAL--EAVAERLGGKPPRKVIVKAPKIVSIV  985
             +AL  E V   ++GK   KVI  + K+V+IV
Sbjct  800  EVALANEKVQAEIAGKDIIKVIAVPNKLVNIV  831


 Score =  137 bits (505),  Expect = 3e-33, Method: Compositional matrix adjust.
 Identities = 76/149 (52%), Positives = 105/149 (71%), Gaps = 12/149 (8%)

Query  30   IEEKWQDIWESEGTFWAANVSGELTDSKGRHADGRQSFFAMDMFPYPSGKGLHVGHPLGY  89
            IE KWQ +W  + TF            K     ++  F+A+DMFPYPSG GLHVGHP GY
Sbjct  9    IEPKWQAFWADNHTF------------KTGTDASKPKFYALDMFPYPSGAGLHVGHPEGY  56

Query  90   LATDVVSRYHRMKGENVLHAMGYDAFGLPAEQYAVQTGQHPRITTEQNIANMRRQLRRMG  149
             ATD++SR+ R +G+NVLH+MG DAFGLPAEQYA++TG++P   T +NIAN +RQ+  +G
Sbjct  57   TATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALG  116

Query  150  LSFDDRRSFATIEPEYVRWTQWIFSRIYD  178
            +S+D  R   T +P+Y +WTQWIF+++Y+
Sbjct  117  FSYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1655) BLC1_0721 in NC_017216


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  488 bits (1841),  Expect = 6e-139, Method: Compositional matrix adjust.
 Identities = 332/752 (45%), Positives = 481/752 (64%), Gaps = 71/752 (9%)

Query  237  LAYISKSPVNWCPGLGTVLANEEVTAEGRSERGNFPVFQRELRQWSMRITAYGHRLIEDL  296
            LAY +  PVNW   LGT +ANEEV ++G SERG +PV ++ +RQW ++ITAY++RL+EDL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  297  DSIDWPEKVKLMQRNWIGESHGASVHFKVPVDGEMADMEIYTTRPDTLFGATFCVVSPEH  356
            + +DWPE +K MQRNWIG S GA+V FKV   +   D  ++TTRPDTLFGAT+ V++PEH
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDK--DFTVFTTRPDTLFGATYAVLAPEH  265

Query  357  PMLEHVPQSWPEGVDPAWTGGYATPSEAVSAYRELAEAKTAADRVADNGEKTGLFTGLYA  416
            ++++ +  S                +EAV+ Y+  A  K+   R     EKTG+ TG YA
Sbjct  266  ALVDAITTS--------------DQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYA  311

Query  417  INPITGAKLPVFTADYVLMDYGTGAIMAVPGGDQRDYDFAVKYGLPVIYTVAPLPDSGDD  476
            INP+ G  +PV  ADYVL  YGTGAIMAVP+ D+RD +FA ++ L +I    P+ ++G+ 
Sbjct  312  INPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDII----PVLEGGN-  366

Query  477  LANYEGTAPFVSHDGIVINSAVDATWARGDALCLDGMRVDDAIAAVTTWLEEAQVGKGAT  536
                   A+F ++DG+ INS             LDG+    AIA +  WLE   VG+   
Sbjct  367  ----VEEAAF-TEDGLHINSD-----------FLDGLDKASAIAKMVEWLEAEGVGNENV  410

Query  537  SYRLRDWLFSRQRYWGEPFPIVYDEHEVPHLVPDSMLPINLPDVPDYSPKTFDPEDSQSS  596
            +YRLRDWLFSRQRYWGEP+PI+  E+  +  VP+S LP+ LP   D  P         ++
Sbjct  411  TYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPS--------GT  462

Query  597  PEAPLSRNEDWVNVTLDLGDGPKTYHHDTNTMPNWAGSCWYYMRYLNPHDTEHMVERDEY  656
             E+PL+   DW++VT +  DG K  +++TNTMP+WAGS WYY+RY++PH+TE + + +  
Sbjct  463  GESPLANVTDWLEVTRE--DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELL  519

Query  657  DYWMGPKHSPAAGQAGGVDLYVGGVEHAVLHLLYSRFWHKILFDLGYVDSFEPFHKLFNQ  716
              W+             VD+YVGG EHAVLHLLY+RFWHK+L+DLG V + EPF+KLFNQ
Sbjct  520  KQWL------------PVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQ  567

Query  717  GMIQAYAYTDDRGQYVPAEDVQESEVDGKTVYTYEGEPVNREFGKMGKSLKNIVTPDYMY  776
            GMI + +Y D RG  V+++ V+    DG       GE +++  +KM+KSLKN+V PD + 
Sbjct  568  GMILGTSYRDSRGALVATDKVEKR--DGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVV  625

Query  777  DHYGADTFRLYEMSMGPLDESRPWNTRNVVGGMRFLQRLWRNVIDENTGEVTVTDDAMDE  836
            ++YGADT+R+YEM MGPLD S +W+   + G+ +FL+R+ R +   +  E     +A+D 
Sbjct  626  EQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITE--ENSGALD-  682

Query  837  RTLKLLNNTIAEVTGEMEAMRPNTAIAKLIVLNNHLTGMNGVPRAAVEPLVLMVAPIAPH  896
               K+ N+T+  VT +++ M+ NTAIA+L+V+ N     + +       +V ++AP+APH
Sbjct  683  ---KVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPH  739

Query  897  IAEELWNRL-GHDESLAHHPWPQADERYVGQDTVTAVVQIKGKVRAKLEVSADIDPDELE  955
            ++EELW+ L + +ES++  PWP  DE  + ++ V  VVQIKGKV+AKL V+ D+  +EL+
Sbjct  740  LGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQ  799

Query  956  KMAL--EAVAERLGGKPPRKVIVKAPKIVSIV  985
             +AL  E V   ++GK   KVI  + K+V+IV
Sbjct  800  EVALANEKVQAEIAGKDIIKVIAVPNKLVNIV  831


 Score =  137 bits (505),  Expect = 3e-33, Method: Compositional matrix adjust.
 Identities = 76/149 (52%), Positives = 105/149 (71%), Gaps = 12/149 (8%)

Query  30   IEEKWQDIWESEGTFWAANVSGELTDSKGRHADGRQSFFAMDMFPYPSGKGLHVGHPLGY  89
            IE KWQ +W  + TF            K     ++  F+A+DMFPYPSG GLHVGHP GY
Sbjct  9    IEPKWQAFWADNHTF------------KTGTDASKPKFYALDMFPYPSGAGLHVGHPEGY  56

Query  90   LATDVVSRYHRMKGENVLHAMGYDAFGLPAEQYAVQTGQHPRITTEQNIANMRRQLRRMG  149
             ATD++SR+ R +G+NVLH+MG DAFGLPAEQYA++TG++P   T +NIAN +RQ+  +G
Sbjct  57   TATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALG  116

Query  150  LSFDDRRSFATIEPEYVRWTQWIFSRIYD  178
            +S+D  R   T +P+Y +WTQWIF+++Y+
Sbjct  117  FSYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1656) leuS in NC_013714


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  488 bits (1841),  Expect = 6e-139, Method: Compositional matrix adjust.
 Identities = 335/754 (45%), Positives = 475/754 (63%), Gaps = 73/754 (9%)

Query  237  LAYISKSPVNWCPGLGTVLANEEVTAEGKSERGNFPVFQRELRQWSMRITAYGHRLIEDL  296
            LAY +  PVNW   LGT +ANEEV ++G SERG +PV ++ +RQW ++ITAY++RL+EDL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  297  DGIDWPEKVKLMQRNWIGESHGASVHFTVETPNGIRDMEIYTTRPDTLFGTTFAVVSPEH  356
            + +DWPE +K MQRNWIG S GA+V F V   +  +D  ++TTRPDTLFG+T+AV++PEH
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD--KDFTVFTTRPDTLFGATYAVLAPEH  265

Query  357  HLLADVPDEWPAETPENWKGGYATPVEAVQSYRLAAEAKTAKDRVDEAGEKTGLFTGLYA  416
             L+  +                +   EAV  Y+  A  K+   R D A EKTG+ TG YA
Sbjct  266  ALVDAITT--------------SDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYA  311

Query  417  INPITGAKLPLFTADYVLMDYGTGAIMAVPGGDQRDYDFAVKFGLPVIYTVKPLPESGDD  476
            INP+ G  +P+  ADYVL  YGTGAIMAVP+ D+RD +FA +F L +I    P+ E+G+ 
Sbjct  312  INPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDII----PVLEGGN-  366

Query  477  LADYEGKAPFVSHDGIVINSSVASTKTKGDALSLDGLRVDEAIDKVNAWLESAGVGKGTV  536
                   A+F ++DG+ INS             LDGL    AI K+  WLE+ GVG+  V
Sbjct  367  ----VEEAAF-TEDGLHINSDF-----------LDGLDKASAIAKMVEWLEAEGVGNENV  410

Query  537  SYRLRDWLFSRQRYWGEPFPIVYGEDGTPHLLPDEQLPINLPDVPDYSPKTFDPEDAESN  596
            +YRLRDWLFSRQRYWGEP+PI+  EDGT+  +P+ +LP+ LP   D  P         + 
Sbjct  411  TYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPS--------GT  462

Query  597  PEAPLSRNEDWVKVELDLGDGKKTYYRDTNTMPNWAGSCWYYMRYLDPTDTEHMVEKDEY  656
             E+PL+   DW+ V  + G   +   R+TNTMP+WAGS WYY+RY+DP +TE + + +  
Sbjct  463  GESPLANVTDWLEVTREDGVKGR---RETNTMPQWAGSSWYYLRYIDPHNTEKLADEELL  519

Query  657  DYWMGPNHNETTGKAGGVDLYIGGVEHAVLHLLYSRFWHKVLFDLGFVDSAEPFHKLFNQ  716
              W+             VD+Y+GG EHAVLHLLY+RFWHKVL+DLG V + EPF+KLFNQ
Sbjct  520  KQWL------------PVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQ  567

Query  717  GMIQAYAYTDDRGQYVPAAEVVEGPADANGEPTFTWNGEHANREFGKMGKSLKNIITPDD  776
            GMI + +Y D RG  V++  V    +      T    GE+ ++  +KM+KSLKN++ PDD
Sbjct  568  GMILGTSYRDSRGALVATDKVEKRDGSFFHVET----GEELEQAPAKMSKSLKNVVNPDD  623

Query  777  MYENYGADTFRLYEMGMGPLAESRPWNTRNVVGSMRFLQRLWRNVIDETTGEVRVSEGDL  836
            + E+YGADT+R+YEM MGPL  S +W+   + GS +FL+R+ R +      E   + G L
Sbjct  624  VVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITE--ENSGAL  681

Query  837  DSKTLKLLNNTIADVTVEMEAMRPNTAIAKLIVLNNHLTGLDDVPRAAIEPLILMLSPIA  896
            D    K+ N+T+  VT +++ M+ NTAIA+L+V+ N     D +       ++ +++P+A
Sbjct  682  D----KVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFA  737

Query  897  PHICEELWNRL-GHDESLAHADWPKADERYVGQDTVTAVVQIKGKVRAKLEVTPDIDPKE  955
            PH+ EELW+ L + +ES++   WP  DE  + ++ V  VVQIKGKV+AKL V+ D+   E
Sbjct  738  PHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREE  797

Query  956  LEQMAL--EAVADRLGGKEPRKVIVKAPKIVSIV  987
            L+++AL  E V   ++GK+  KVI  + K+V+IV
Sbjct  798  LQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIV  831


 Score =  142 bits (523),  Expect = 9e-35, Method: Compositional matrix adjust.
 Identities = 77/150 (52%), Positives = 108/150 (72%), Gaps = 12/150 (8%)

Query  29   GVEEKWQKIWDDEGTFWAANVNGELKDGKGHNAEGRPSYFAMDMFPYPSGKGLHVGHPLG  88
            ++E KWQ +W D+ TF            K     ++P ++A+DMFPYPSG GLHVGHP G
Sbjct  8    AIEPKWQAFWADNHTF------------KTGTDASKPKFYALDMFPYPSGAGLHVGHPEG  55

Query  89   YLATDVVSRYHRMKGENVLHAMGYDAFGLPAEQYAVQTGQHPRITTEQNIANMRRQLHRM  148
            Y ATD++SR+ R +G+NVLH+MG DAFGLPAEQYA++TG++P   T +NIAN +RQ++ +
Sbjct  56   YTATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINAL  115

Query  149  GLSFDNRRSFATIDPGYVRWTQWIFSRIYD  178
            G+S+D  R   T DP Y +WTQWIF+++Y+
Sbjct  116  GFSYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1657) Thicy_1389 in NC_015581


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  488 bits (1840),  Expect = 6e-139, Method: Compositional matrix adjust.
 Identities = 348/864 (41%), Positives = 543/864 (63%), Gaps = 79/864 (9%)

Query  11   YQPQTLEAAIQQVWQDQKVFEVTEDPTKEKYYCLSMFPYPSGR-LHMGHVRNYTIGDVIS  69
            Y+  ++E+  Q  W D+  F    D++K K+Y L MFPYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  70   RYQRMLGKNVLQPMGFDAFGLPAENAAMQNKVAPAAWTYDNMDYMRNQLQQLGLGYDWSR  129
            R++R  G NVL+PMG DAFGLPAE+ AM+    PA  T +N+   + Q++ LG++YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  130  EVATCSPDYYRWEQWLFTKLYEKGLVYRKLSVVNWDPVDQTVLANEQVI-DGKGWRSGAP  188
            EV T  P+YY+W QW+FTKLYEKGL Y     VNW     T +ANE+V+ DG + R+G P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  189  VERKEIAQWFLKITDYAdellqdleqleGWPEQVKTMQRNWIGKSTGMEVEFPLVESIDG  248
            V RK + QW LKIT YA E L +  +  +WPE +K MQRNWIGKSTG +V F + ++  +
Sbjct  184  VVRKPMRQWMLKITAYA-ERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  249  FDATLKVYTTRPDTLMGVSYVAVAADHPLAKQAALINEPLAQFIEECSHISTAEADME--  306
            F     V+TTRPDTL G +Y  +A++H+L    A+     A+ + +  + ++  +D+   
Sbjct  243  F----TVFTTRPDTLFGATYAVLAPEHALV--DAITTSDQAEAVADYKRQASLKSDLART  296

Query  307  --TMEKKGVDTGLRVRHPISNEVVPVWAANFVLMGYGTGAVMAVPAHDQRDFEFAQKYRL  364
              + EK GV TG    +P++   +PVW A++VL +YGTGA+MAVPAHD+RD EFA+++ L
Sbjct  297  DLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNL  356

Query  365  PIKPVIRPADQDSVDVSEQAYTERGVLFNSGELDGLDFNaamdkladllgakdlgRKQTN  424
             I PV+     ++ +V E A+TE G+ +NS+ LDGLD  +A+ K+ + L A ++G  +  
Sbjct  357  DIIPVL-----EGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVT  411

Query  425  FRLRDWGISRQRYWGCPIPMIYCAECDPVPVPEQDLPVRLP--EDVVPDGAG-SPLAKLD  481
            +RLRDW +SRQRYWG PIP+I   +  + +VPE +LP+ LP   D+ P G+G SPLA++ 
Sbjct  412  YRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVT  471

Query  482  SFQNCTCPKCGGAAKRESDTFDTFFESSWYYARYACADNDQAMLDER-ANYWLPVDQYIG  540
               + T    G  ++RE++T      SSWYY RY  ++N + + DE   + WLPVD Y+G
Sbjct  472  DWLEVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVG  530

Query  541  GIEHAILHLLYARFFHKLMRDVGLVNSDEPFKNLLTQGMVLMNG----------------  584
            G EHA+LHLLYARF HK++ D+G+V + EPF++L+ QGM+L  +                
Sbjct  531  GAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEK  590

Query  585  ------------------AKMSKSKGNTVDPQGLIEKYGADTVRLFIMFAAPPEQSLEWS  626
                              AKMSKS  N V+P++++E+YGADT+R++ MF +P + S+ WS
Sbjct  591  RDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWS  650

Query  627  DSGVEGAHRFLNRVWRLVHQHVETSPVVVACQSNEGLSKEQKALRLKLHESLQKVSDDIG  686
            + G+EG+++FL+RV RL+      +   ++ +++ +L K         +E+++ V+++++
Sbjct  651  EEGLEGSRKFLDRVYRLI------TTKEITEENSGALDKV-------YNETVKAVTEQVD  697

Query  687  RRLQFNTAIAACMELLNALAKFEDDSEQGRALMQEALELLVLMLSPMVPHITQALWEQLG  746
             +++FNTAIA        L  F + +++   L  +    +V +++P  PH+ + LW+ L 
Sbjct  698  -QMKFNTAIA-------QLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALT  749

Query  747  QPGLVLD-VTWPKVDNAALVQDEIELMVQVNGKLRGkiavakdaekaailaaakaedSVH  805
             +G  +  V WP  D++ LV++++E++VQ++GK+++K+ VAKD  +  +   A A++ V+
Sbjct  750  ASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQ  809

Query  806  KFIDGKELVKEILVPGRLVNFVVK  829
              I GK+++K I VP +LVN+V+K
Sbjct  810  AEIAGKDIIKVIAVPNKLVNIVIK  833

1658) MASS_4924 in NC_021282


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  488 bits (1841),  Expect = 7e-139, Method: Compositional matrix adjust.
 Identities = 343/739 (47%), Positives = 497/739 (68%), Gaps = 65/739 (8%)

Query  224  LVYQSDSVVNWCPGLGTVLANEEVTADGRSERGNFPVFRKRLRQWMMRITAYSDRLIDDL  283
            L Y+++  VNW   LGT +ANEEV +DG SERG +PV RK +RQWM++ITAY++RL++DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  284  DVLDWPDKVKTMQRNWIGRSQGASVLFGAPGVG-DIEVFTTRPDTLFGATYMVLAPEHPL  342
            + +DWP+ +K MQRNWIG+S GA+V F   + + D+ VFTTRPDTLFGATY VLAPEH+L
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  343  VDQLAADVWPQDTDPRWTGGQDSPRAAIEQYRRSIAAKSDLERQE-NKEKTGVFTGAYAT  401
            VD +++                    A+ +Y+R  + KSDL R +  KEKTGV TG+YA 
Sbjct  268  VDAITTS---------------DQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAI  312

Query  402  NPVSGKPVPVFIADYVLLGYGTGAIMAVPGHDQRDWDFANTFGLPVQEVISGGDVTEAAY  461
            NPV+GK +PV IADYVL +YGTGAIMAVP+HD+RDW+FA+ F L +  V+ GG+V EAA+
Sbjct  313  NPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEAAF  372

Query  462  TGDGALVNSDYLDGLDVEAAKVEVTRRLVKDGRGESRIEYKLRDWLFARQRYWGEPFPIV  521
            T DG  +NSD+LDGLD  +A   +  +L  +G G+  + Y+LRDWLF+RQRYWGEP+PI+
Sbjct  373  TEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPII  432

Query  522  YDEDGRPRALGedvlpvelpevedYAPVsfdpddassepspplsKAADWVNVELDLGDGL  581
              EDG + A+ E  LP+ LP   D  P        S+   +PL++ +DW++V  +  DG+
Sbjct  433  HWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTDWLEVTRE--DGV  482

Query  582  KHYTRDTNVMPQWAGSSWYELRYADPDNAEAFCDKENEAYWLGPRPAEHGPNDPGGVDLY  641
            K   R+TN MPQWAGSSWY LRY DP+N+E + D E    WL              VD+Y
Sbjct  483  KG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWL-------------PVDIY  528

Query  642  VGGMEHAVLHLLYSRFWHKVLYDLGHVSSREPYRRLLNQGYIQAHAYTDARGMYVPAAEV  701
            VGG EHAVLHLLY+RFWHKVLYDLG V+++EP+++L+NQG I + +Y D+RG  V++  V
Sbjct  529  VGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKV  588

Query  702  TEENGRFFY--RGAEVQQEFGKIGKSLKNSISPDDICDNYGADTLRVYEMSMGPLELSRP  759
               +G FF    G E++Q  +K++KSLKN ++PDD+ ++YGADTLRVYEM MGPL+ S +
Sbjct  589  EKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIA  648

Query  760  WATKDVVGAHRFLQRAWRVVVDEETGKIRVTTDDLTSEDTLRALHKTIAGVTEDYAALRN  819
            W+  ++ G+++FL+R  R++   E     +T ++  + D  +  + T+ +VTE+   ++ 
Sbjct  649  WSEEGLEGSRKFLDRVYRLITTKE-----ITEENSGALD--KVYNETVKAVTEQVDQMKF  701

Query  820  NTAAAKLIEYTNHLTKE------YPEGAPRaaveplvlmlaplaphlaeelW-SLLGRDD  872
            NTA A+L+ + N   KE      Y+ G  +        ++AP+APHL+EELW +L + ++
Sbjct  702  NTAIAQLMVFVNAANKEDKLFSDYAKGFVQ--------LIAPFAPHLGEELWQALTASGE  753

Query  873  SLAHGPFPESDDRWLVADTVEYPIQVNGKVRGRITVAADAPKGDIEAAALTEEKVLEFLA  932
            S++  P P  D+  LV + VE  +Q++GKV++++ VA D ++ +++  AL++EKV   +A
Sbjct  754  SISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIA  813

Query  933  GATPKKVIVVPGRMVNLVV  951
            G    KVI VP ++VN+V+
Sbjct  814  GKDIIKVIAVPNKLVNIVI  832


 Score =  132 bits (486),  Expect = 9e-32, Method: Compositional matrix adjust.
 Identities = 78/148 (53%), Positives = 98/148 (67%), Gaps = 11/148 (7%)

Query  27   IERRWQQTWADRGTFHVPNPVGSLAPTDGTPIPADKMFVQDMFPYPSGDGLHVGHPLGYI  86
            IE +WQ  WAD  TF             GT  +  K +  DMFPYPSG GLHVGHP GY 
Sbjct  9    IEPKWQAFWADNHTFKT-----------GTDASKPKFYALDMFPYPSGAGLHVGHPEGYT  57

Query  87   ATDVYARFHRMRGANVLHALGFDAFGLPAEQYAVQTGTHPRVRTEANIVNYKRQLGRLGL  146
            ATD+ +RF R +G NVLH++G DAFGLPAEQYA++TG +P   T  NI N+KRQ+  LG+
Sbjct  58   ATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGF  117

Query  147  GHDSRRSFATTDVDFYKWTQWIFLQIYN  174
            + D  R   TTD ++YKWTQWIF ++Y+
Sbjct  118  SYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1659) leuS in NC_010120


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  488 bits (1840),  Expect = 7e-139, Method: Compositional matrix adjust.
 Identities = 357/886 (41%), Positives = 539/886 (61%), Gaps = 71/886 (8%)

Query  43   YRPAAIEPAAQKKWDDARIFNVSEDASKPKYYCLSMFPYPSGK-LHMGHVRNYTIGDVLS  101
            Y  +AIEP  Q  W D + F+ + DASKPK+Y L MFPYPSG  LH+GH   YT  D+LS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  102  RFKRLNGFNVMQPMGWDAFGMPAENAAMKNNVAPAAWTYDNIEYMKTQLKSLGFAIDWAR  161
            RFKR +G NV++PMGWDAFG+PAE+ AM     PA  T +NI   K Q+++LGF+ DW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  162  ETATCKPEYYRWEQWLFTKLFEKGIVYRKNGTVNWDPVDQTVLANEQVI-DGRGWRSGAL  220
            E  T  P+YY+W QW+FTKL+EKG+ Y  +  VNW     T +ANE+V+ DG + R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  221  IEKREIPMYYFKITDYAEELLNDLDKLEHWPEQVKTMQRNWIGKSRGMTVRFAVSDDSKQ  280
            + ++ +    +KIT YAE LL+DL+ ++ WPE +K MQRNWIGKS G  V F V D  K+
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  281  GLEGDYARFLQVYTTRPDTLMGATYVavaaehplataaaaDKPELQAFIAECKAGSVAEA  340
                     + V+TTRPDTL GATY         A   A   ++    +A+ K  +   +
Sbjct  243  ---------FTVFTTRPDTLFGATYA--VLAPEHALVDAITTSDQAEAVADYKRQASLKS  291

Query  341  DMA----TMEKKGVPTGRYVVNPLNGDKLEVWIANYVLWGYGDGAVMAVPAHDERDFEFA  396
            D+A    + EK GV TG Y +NP+NG  + VWIA+YVL +YG GA+MAVPAHDERD EFA
Sbjct  292  DLARTDLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFA  351

Query  397  TKYSLPKKQVI---AVGDNAFDANQWQEWYGDKENGVLVNSGDLDGMNFQTAFDAIAAKL  453
             +++L    V+    V + AF            E+G+ +NS+ LDG++  +A+  +   L
Sbjct  352  KQFNLDIIPVLEGGNVEEAAF-----------TEDGLHINSDFLDGLDKASAIAKMVEWL  400

Query  454  QSQGAGEPKTQYRLRDWGISRQRYWGCPIPIVHCEQCGDVPVPADQLPVVLP--ENVVPD  511
            +++G G+ +  YRLRDW +SRQRYWG PIPI+H E+    +VP  +LP+VLP   ++ P 
Sbjct  401  EAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPS  460

Query  512  GMG-SPLAKMPEFYETACPCCGGAAKRETDTMDTFMESSWYFFRYMSPKFSDGMVSAEAA  570
            G G SPLA++ +  E +    G  ++RET+TM     SSWY++RY+ P  ++ +   E  
Sbjct  461  GTGESPLANVTDWLEVTRE-DGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELL  519

Query  571  KYWGAVDQYIGGIEHAILHLLYARFFTKLMRDEGLVNVDEPFERLLTQGMVVCETYYREN  630
            K W +VD Y+GG EHA+LHLLYARF  K++ D G+V   EPF++L+ QGM++  +Y   +
Sbjct  520  KQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY--RD  577

Query  631  DKGGKDWINPADVELTFDDKGRPVSAVLKADGLPVVISGTEKMSKSKNNGVDPQELINAY  690
             +G+   +    VE       +  ++ +  +    +  +  KMSKS +N V+P+++++ Y
Sbjct  578  SRGAL--VATDKVE-------KRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQY  628

Query  691  GADTARLFMMFAAPPEQSLEWSDSGVEGAHRFLRRLWRTVYEYLKQGGAVKAFAGNQDGL  750
            GADT R++ MF +P + S+ WS+ G+EG+++FL R+ R +        + K ++ ++ G 
Sbjct  629  GADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLI--------TTKEITEENSG-  679

Query  751  SKELKDLRHKLHSTIAKVSDDYGRRQQFNTAIAAVMELLNQYDKTDTGSEQGRAVAQEVL  810
                  L    + T+  V+++ ++  +FNTAIA +M ++N  +K D        +  +  
Sbjct  680  -----ALDKVYNETVKAVTEQVDQM-KFNTAIAQLMVFVNAANKEDK-------LFSDYA  726

Query  811  ETAVRLLWPIVPHICETLWSEL--NGAKLWEAGWPAVDEAALVKSEIEVMVQVNGKLRGK  868
               V+L+ P+ PH+ E LW  L  +G  +    WP+ DE+ LV +++E++VQ++GK+++K
Sbjct  727  KGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAK  786

Query  869  ITvaadaskadleaaalategavkFMEGKPAKKIIVVPGRLVNIVV  914
            + VA D S+ +L+  ALA E     + GK   K+I VP +LVNIV+
Sbjct  787  LVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

1660) leuS in NC_006361


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  488 bits (1840),  Expect = 8e-139, Method: Compositional matrix adjust.
 Identities = 350/740 (48%), Positives = 500/740 (68%), Gaps = 66/740 (8%)

Query  220  LVYQTDSMVNWCPGLGTVLSNEEVTAEGRSERGNFPVFRKRLWQWMMRITAYAdrlvddl  279
            L Y+++  VNW   LGT ++NEEV ++G SERG +PV RK ++QWM++ITAYA+RL++DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  280  dlldWPENVKAMQRNWIGRSRGAQVRFDSPAGQIE--VFTTRPDTLFGATYVVLAPEHDL  337
            + +DWPE++K MQRNWIG+S GA+V F     + +  VFTTRPDTLFGATY VLAPEH L
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  338  VDALAAAQWPADTDPRWTGGAATPAEAVAQYRKSIAAKSDLERQE-NKEKTGVFLGVHAV  396
            VDA+++++                AEAVA+Y++  + KSDL R +  KEKTGV  G  A+
Sbjct  268  VDAITTSD---------------QAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAI  312

Query  397  NPVNGARVPIFIADYVLSGYGTGAIMAVPGHDQRDWEFATAFGLPIVEVISGGDITAAAH  456
            NPVNG  +P+ IADYVL++YGTGAIMAVP+HD+RDWEFA  F L I+ V+ GG++  AA 
Sbjct  313  NPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEAAF  372

Query  457  TGEGELVNSDYLNGLSVEEAKATVIGRLEADGHGTGTIQYKLRDWLFARQRYWGEPFPIV  516
            T +G  +NSD+L+GL    A A ++ +LEA+G G   + Y+LRDWLF+RQRYWGEP+PI+
Sbjct  373  TEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPII  432

Query  517  YDEDGAPHALPESMLPVRLPELDDFAPVTFdpddadsepsppLAKATDWVHVELDLGDGP  576
              EDG++ A+PES LP+ LP   D+ P             +PLA+ TDW++V  +  DG 
Sbjct  433  HWEDGTSTAVPESELPLVLPVTKDIRPSG--------TGESPLANVTDWLEVTRE--DGV  482

Query  577  KKYRRDTNVMPNWAGSSWYQLRYADPTNADAFCAKENEQYWLGPRTAEHGPDDPGGVDLY  636
            K  RR+TN MP+WAGSSWY LRY DP N++ +   E  + WL              VD+Y
Sbjct  483  KG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWL-------------PVDIY  528

Query  637  VGGVEHAVLHLLYARFWQKVLFDLGYVSSSEPYRRLFNQGYIQAFAYTDPRGAYVPAAEV  696
            VGG EHAVLHLLYARFW+KVL+DLG V++ EP+++LFNQG I + +Y D+RGA V++  V
Sbjct  529  VGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKV  588

Query  697  VERDGAFFWTDATGTEIEVSQEYGKIGKSLKNAISPDEVCDQFGADTFRFYEMSMGPLDT  756
              RDG+FF  + TG E+E +   +K++KSLKN ++PD+V +Q+GADT+R YEM MGPLD+
Sbjct  589  EKRDGSFFHVE-TGEELEQAP--AKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  757  SRPWSTKDVVGAHRFLQRVWRLVVDEETGASRVTEDAPTDETLRFLHRTIAGVDEDFAAL  816
            S +WS  ++ G+++FL+RV RL+   E     +TE+ +      + + T+ +V E+   +
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLITTKE-----ITEENSGALDKVY-NETVKAVTEQVDQM  699

Query  817  RDNTAGAKLIELTN------HLTKSYPSGTPRAAVEPLVLMLAPLAPHVAEELWERL-GH  869
            + NTA A+L+ + N       L   Y+ G        +V ++AP+APH++EELW+ L + 
Sbjct  700  KFNTAIAQLMVFVNAANKEDKLFSDYAKG--------FVQLIAPFAPHLGEELWQALTAS  751

Query  870  SESLAHGPFPVADPAWLVEETVEYPIQVNGKVRSRIQVPadadnaaieaaaladekiaal  929
            +ES++  P P  D + LVE+ VE  +Q++GKV++++ V+ D     ++  ALA+EK+ A 
Sbjct  752  GESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAE  811

Query  930  laGATPRKLIVVPGRLVNIV  949
            +AG    K+I VP +LVNIV
Sbjct  812  IAGKDIIKVIAVPNKLVNIV  831


 Score =  115 bits (421),  Expect = 1e-26, Method: Compositional matrix adjust.
 Identities = 77/147 (53%), Positives = 106/147 (73%), Gaps = 10/147 (6%)

Query  24   IERRWQQRWLERGTFHAPNPTGPLAGPTATLPADKLFVQDMFPYPSGAGLHVGHPLGYIA  83
            IE +WQ  W +  TF +        G  A+ P  K++  DMFPYPSGAGLHVGHP GY A
Sbjct  9    IEPKWQAFWADNHTFKT--------GTDASKP--KFYALDMFPYPSGAGLHVGHPEGYTA  58

Query  84   TDVFARYHRMRGRNVLHALGYDAFGLPAEQYAVQTGAHPRDTTESNIATMQrqldrlglg  143
            TD+++R+ R +G+NVLH++G DAFGLPAEQYA++TG +P + T  NIA  +RQ++ LG++
Sbjct  59   TDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFS  118

Query  144  hdrrrSFATTDPEYYRWTQWIFLQIYN  170
             D+ R   TTDP+YY+WTQWIF ++Y+
Sbjct  119  YDWDREVNTTDPNYYKWTQWIFTKLYE  145

1661) leuS in NC_017834


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  488 bits (1840),  Expect = 8e-139, Method: Compositional matrix adjust.
 Identities = 334/752 (45%), Positives = 480/752 (64%), Gaps = 71/752 (9%)

Query  237  LAYISKSPVNWCPGLGTVLANEEVTAEGRSERGNFPVFQRELRQWSMRITAYGHRLIEDL  296
            LAY +  PVNW   LGT +ANEEV ++G SERG +PV ++ +RQW ++ITAY++RL+EDL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  297  DSIDWPEKVKLMQRNWIGESHGASVHFKVPVDGEMADMEIYTTRPDTLFGATFCVVSPEH  356
            + +DWPE +K MQRNWIG S GA+V FKV   +   D  ++TTRPDTLFGAT+ V++PEH
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDK--DFTVFTTRPDTLFGATYAVLAPEH  265

Query  357  PMLEHVPQSWPEGVDPAWTGGYATPSEAVSAYRELAEAKTAADRVADNGEKTGLFTGLYA  416
            ++++ +  S                +EAV+ Y+  A  K+   R     EKTG+ TG YA
Sbjct  266  ALVDAITTS--------------DQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYA  311

Query  417  INPITGAKLPVFTADYVLMDYGTGAIMAVPGGDQRDYDFAIKYGLPVIYTVAPLPDSGDD  476
            INP+ G  +PV  ADYVL  YGTGAIMAVP+ D+RD +FA ++ L +I    P+ ++G+ 
Sbjct  312  INPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDII----PVLEGGN-  366

Query  477  LANYEGTAPFVSHDGIVINSTVDATWARGDALCLDGMRVDDAIAVVTTWLEEAQVGKGAT  536
                   A+F ++DG+ INS             LDG+    AIA +  WLE   VG+   
Sbjct  367  ----VEEAAF-TEDGLHINSD-----------FLDGLDKASAIAKMVEWLEAEGVGNENV  410

Query  537  SYRLRDWLFSRQRYWGEPFPIVYDEHEVPHLVPDSMLPINLPDVPDYSPKTFDPEDSQSS  596
            +YRLRDWLFSRQRYWGEP+PI+  E+  +  VP+S LP+ LP   D  P         ++
Sbjct  411  TYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPS--------GT  462

Query  597  PEAPLSRNEDWVKVTLDLGDGPKTYHHDTNTMPNWAGSCWYYMRYLNPHDTEHMVERDEY  656
             E+PL+   DW+ VT +  DG K  +++TNTMP+WAGS WYY+RY++PH+TE + + +  
Sbjct  463  GESPLANVTDWLEVTRE--DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELL  519

Query  657  DYWMGPKHSLAAGQAGGVDLYVGGVEHAVLHLLYSRFWHKILFDLGYVDSFEPFHKLFNQ  716
              W+             VD+YVGG EHAVLHLLY+RFWHK+L+DLG V + EPF+KLFNQ
Sbjct  520  KQWL------------PVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQ  567

Query  717  GMIQAYAYTDDRGQYVPAEDVQESEVDGKTVYTYEGEPVNREFGKMGKSLKNIVTPDYMY  776
            GMI + +Y D RG  V+++ V+    DG       GE +++  +KM+KSLKN+V PD + 
Sbjct  568  GMILGTSYRDSRGALVATDKVEKR--DGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVV  625

Query  777  DHYGADTFRLYEMSMGPLDESRPWNTRNVVGGMRFLQRLWRNVIDENTGEVTVTDDAMDE  836
            ++YGADT+R+YEM MGPLD S +W+   + G+ +FL+R+ R +   +  E     +A+D 
Sbjct  626  EQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITE--ENSGALD-  682

Query  837  RTLKLLNNTIAEVTGEMEAMRPNTAIAKLIVLNNHLTGMDGVPRAAVEPLVLMVAPIAPH  896
               K+ N+T+  VT +++ M+ NTAIA+L+V+ N     D +       +V ++AP+APH
Sbjct  683  ---KVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPH  739

Query  897  IAEELWNRL-GHGESLAHHPWPQADERYVGQDTVTAVVQIKGKVRAKLEVSADIDPDELE  955
            ++EELW+ L + GES++  PWP  DE  + ++ V  VVQIKGKV+AKL V+ D+  +EL+
Sbjct  740  LGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQ  799

Query  956  KMAL--EAVAERLGGKPPRKVIVKAPKIVSIV  985
             +AL  E V   ++GK   KVI  + K+V+IV
Sbjct  800  EVALANEKVQAEIAGKDIIKVIAVPNKLVNIV  831


 Score =  138 bits (508),  Expect = 2e-33, Method: Compositional matrix adjust.
 Identities = 76/149 (52%), Positives = 105/149 (71%), Gaps = 12/149 (8%)

Query  30   IEKKWQDIWESEGTFWAANVSGELTDGKGSHADGRQSFFAMDMFPYPSGKGLHVGHPLGY  89
            IE KWQ +W  + TF            K +   ++  F+A+DMFPYPSG GLHVGHP GY
Sbjct  9    IEPKWQAFWADNHTF------------KTGTDASKPKFYALDMFPYPSGAGLHVGHPEGY  56

Query  90   LATDVVSRYHRMKGENVLHAMGYDAFGLPAEQYAVQTGQHPRITTEQNIANMRRQLRRMG  149
             ATD++SR+ R +G+NVLH+MG DAFGLPAEQYA++TG++P   T +NIAN +RQ+  +G
Sbjct  57   TATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALG  116

Query  150  LSFDDRRSFATIEPGYVRWTQWIFSRIYD  178
            +S+D  R   T +P Y +WTQWIF+++Y+
Sbjct  117  FSYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1662) DGo_CA2006 in NC_017790


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  487 bits (1838),  Expect = 1e-138, Method: Compositional matrix adjust.
 Identities = 359/849 (43%), Positives = 519/849 (62%), Gaps = 61/849 (7%)

Query  21   YNPHAFEHAWQEKWEHDGLYRFDPEAPGEKHYAMTMFPYPSG-NLHIGHWYANVAPDAHA  79
            Y+  A+E  WQ  W ++  ++ + +A+  K YA+ MFPYPSG  LH+GH  +  A D  +
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  80   RWMRMRGHNVLFPMGFDAFGLpaenaaiknninpaaWTYSNIAHMTGQFQRMGTMIDWSR  139
            R  R +GHNVL PMG DAFGLPAE+ A+    +PA  T  NIA+   Q++ +G   DW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  140  RFATCDPEYYRWNQWFFIQFYKRGLAYKRESLVNWDPVDQTVLANEQVI-DGRGDRSGAL  198
               T DP+YY+W QW+F ++Y +GLAY  E  VNW     T +ANE+V+ DG ++R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  199  IERRLMSQWHFKITDYADELL-DFTHTDMPERVRVMQTNWIGKSVGAEVTFDTPAGPE--  255
            + R+ M QW +KIT YA+ LL D+ + D PE ++ MQ NWIGKS GA+VTF         
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDF  243

Query  256  TVFTTRPDTLMGATFLVLAPEHARVAALTTDEQRAEVEAYVVAAGRRTDVERQQDSGEKT  315
            TVFTTRPDTL GAT+ VLAPEHA V A+TT +Q   V  Y   A+ ++D+ R + + EKT
Sbjct  244  TVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKT  303

Query  316  GVFTGAFATHPITGHQLPIWVADYVLATYGTGSIMAVPAHDERDFAFARRFGLDIREVIR  375
            GV TG++A +P+ G ++P+W+ADYVLA+YGTG+IMAVPAHDERD  FA++F LDI  V+ 
Sbjct  304  GVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL-  362

Query  376  PEGGEPMAGDAEAPYSGEGLIVNSGDFDGLAGGKASIAGIVAALEERGVAKAKTTYRLRD  435
             EGG+      EA+++ +GL +NS+ +DGL  + ++IA +V  LE  GV++ + TYRLRD
Sbjct  363  -EGGNV----EEAAFTEDGLHINSDFLDGLDKA-SAIAKMVEWLEAEGVGNENVTYRLRD  416

Query  436  WLVSRQRYWGTPIPIVYCQKCGAVPVPEDQLPVELPADVEFLP--TGQSPLVLNRAWVET  493
            WL SRQRYWG PIPI+  +   + +VPE +LP+ LP   ++ P  TG+SPL     W+E 
Sbjct  417  WLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEV  476

Query  494  TCPECGGPAERDTDTMDTFVDSSWYMYRYLSPHDDQHPFDPAQARL-LPVDLYTGGIEHA  552
            T  + G  + R+T+TM    +SSWY  RY+ PH+ +   D    +  LPVD+Y GG EHA
Sbjct  477  TRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHA  535

Query  553  ILHLLYSRFWTKVMRDLGLTTQHEPFAHLRNQGIILG-----------------------  589
            +LHLLY+RFW KV+ DLG+    EPF  L NQG+ILG                       
Sbjct  536  VLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSF  595

Query  590  ----------EDNEKMSKSRGNVVDPDDLVREYGVDTVRTYLMFIAPWELGGPWDPQGIN  639
                      +   KMSKS  NVV+PDD+V +YG DT+R Y MF++P + + +W  +G++
Sbjct  596  FHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLE  655

Query  640  GPVKWLGRVWALYFDEKASGPQENVSEADLRYAVHSALKKVGGDFARMSFNTIVAALMEL  699
            G+ K L+RV  L      +  +EN +  D  Y  + ++K V  +  +M FNT +A LM +
Sbjct  656  GSRKFLDRVYRLITTKEIT--EENSGALDKVY--NETVKAVTEQVDQMKFNTAIAQLMVF  711

Query  700  TNTLVKAKRSPVFGTPVWDEALHIFNLMLAPLVPHIAEQIWTERGGVG-SVHVQPWPQVD  758
             N+  K  +  +F+     +    F  ++AP+ PH++E++W    + G S+   PWP  D
Sbjct  712  VNAANKEDK--LFS-----DYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYD  764

Query  759  EAAATRDTVTIGVQVSGKVRGEVSISKTAPQDealaaaravpevarYLEGKAVVKEIYVP  818
            E+    + V I VQ+ GKV++ + ++K  +++E    A A   V   + GK ++K I VP
Sbjct  765  ESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVP  824

Query  819  GRIINIVTS  827
             +++NIV  
Sbjct  825  NKLVNIVIK  833

1663) leuS in NC_014752


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  487 bits (1838),  Expect = 1e-138, Method: Compositional matrix adjust.
 Identities = 359/886 (41%), Positives = 540/886 (61%), Gaps = 71/886 (8%)

Query  5    YRPAAIEPAAQKKWDDARIFNVSEDASKPKYYCLSMFPYPSGK-LHMGHVRNYTIGDVLS  63
            Y  +AIEP  Q  W D + F+ + DASKPK+Y L MFPYPSG  LH+GH   YT  D+LS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RFKRLNGFNVMQPMGWDAFGMPAENAAMKHNVAPAAWTYDNIEYMKTQLKSLGFAIDWER  123
            RFKR +G NV++PMGWDAFG+PAE+ AM     PA  T +NI   K Q+++LGF+ DW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ETATCKPEYYRWEQWLFTKLFEKGIVYRKNGTVNWDPVDQTVLANEQVI-DGRGWRSGAL  182
            E  T  P+YY+W QW+FTKL+EKG+ Y  +  VNW     T +ANE+V+ DG + R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  IEKREIPMYYFKITDYAEELLNDLDKLEHWPEQVKTMQRNWIGKSRGMTVRFAVSDDSKQ  242
            + ++ +    +KIT YAE LL+DL+ ++ WPE +K MQRNWIGKS G  V F V D  K+
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  GLEGDYAKFLQVYTTRPDTLMGATYVavaaehplataaaaGKPELQAFIAECKAGSVAEA  302
                     + V+TTRPDTL GATY         A   A   ++    +A+ K  +   +
Sbjct  243  ---------FTVFTTRPDTLFGATYA--VLAPEHALVDAITTSDQAEAVADYKRQASLKS  291

Query  303  DMA----TMEKKGVPTGRYVVNPLNGDKLEVWIANYVLWGYGDGAVMAVPAHDERDFEFA  358
            D+A    + EK GV TG Y +NP+NG  + VWIA+YVL +YG GA+MAVPAHDERD EFA
Sbjct  292  DLARTDLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFA  351

Query  359  TKYNLPKKQVI---AVGDNAFDANRWQEWYGDKENGVLVNSGDLDGLDFQTAFDAVAAKL  415
             ++NL    V+    V + AF            E+G+ +NS+ LDGLD  +A+  +   L
Sbjct  352  KQFNLDIIPVLEGGNVEEAAF-----------TEDGLHINSDFLDGLDKASAIAKMVEWL  400

Query  416  QSQSAGEPKTQYRLRDWGISRQRYWGCPIPIVHCEQCGDVPVPADQLPVVLP--ENVVPD  473
            ++++ G+ +  YRLRDW +SRQRYWG PIPI+H E+    +VP  +LP+VLP   ++ P 
Sbjct  401  EAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPS  460

Query  474  GMG-SPLAKMPEFYETACPCCGGAAKRETDTMDTFMESSWYFFRYMSPKFSDGMVSAEAA  532
            G G SPLA++ +  E +    G  ++RET+TM     SSWY++RY+ P  ++ +   E  
Sbjct  461  GTGESPLANVTDWLEVTRE-DGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELL  519

Query  533  KYWGAVDQYIGGIEHAILHLLYARFFTKLMRDEGLVNVGEPFERLLTQGMVVCETYYREN  592
            K W +VD Y+GG EHA+LHLLYARF  K++ D G+V   EPF++L+ QGM++  +Y   +
Sbjct  520  KQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY--RD  577

Query  593  DKGGKDWINPADVELTFDDKGRPVSAVLKADGLPIVISGTEKMSKSKNNGVDPQELINAY  652
             +G+   +    VE       +  ++ +  +    +  +  KMSKS +N V+P+++++ Y
Sbjct  578  SRGAL--VATDKVE-------KRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQY  628

Query  653  GADTARLFMMFAAPPEQSLEWSDSGVEGAHRFLRRLWRTVYEYLKQGKAVKAFAGSQDGL  712
            GADT R++ MF +P + S+ WS+ G+EG+++FL R+ R +        + K ++  + G 
Sbjct  629  GADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLI--------TTKEITEENSG-  679

Query  713  SKELKDLRHKLHSTIAKVSDDYGRRQQFNTAIAAVMELLNQYDKTDTGGEQGRAVAQEVL  772
                  L    + T+  V+++ ++  +FNTAIA +M ++N  +K D        +  +  
Sbjct  680  -----ALDKVYNETVKAVTEQVDQM-KFNTAIAQLMVFVNAANKEDK-------LFSDYA  726

Query  773  EAAVRLLWPIVPHICETLWSEL--NGAKLWEAGWPTVDEAALVKSEIEVMVQVNGKLRGK  830
             + V+L+ P+ PH+ E LW  L  +G  +    WP+ DE+ LV +++E++VQ++GK+++K
Sbjct  727  KGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAK  786

Query  831  ITvaadaskadleaaalategavkFMEGKPAKKIIVVPGRLVNIVV  876
            + VA D S+ +L+  ALA E     + GK   K+I VP +LVNIV+
Sbjct  787  LVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

1664) leuS in NC_013016


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  487 bits (1838),  Expect = 1e-138, Method: Compositional matrix adjust.
 Identities = 360/886 (41%), Positives = 539/886 (61%), Gaps = 71/886 (8%)

Query  7    YQPAAIEPAAQKKWDDARIFNVSEDASKPKYYCLSMFPYPSGK-LHMGHVRNYTIGDVLS  65
            Y+ +AIEP  Q  W D + F+ + DASKPK+Y L MFPYPSG  LH+GH   YT  D+LS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  66   RFKLLNGFNVMQPMGWDAFGMPAENAAMKNNVAPAAWTYDNIEYMKTQLKSLGFAIDWER  125
            RFK  +G NV++PMGWDAFG+PAE+ AM     PA  T +NI   K Q+++LGF+ DW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  126  EVATCKPEYYRWEQWLFTKLFEKGIVYRKNGTVNWDPVDQTVLANEQVI-DGRGWRSGAL  184
            EV T  P+YY+W QW+FTKL+EKG+ Y  +  VNW     T +ANE+V+ DG + R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  185  IEKREIPMYYFKITDYAEELLNDLDKLEHWPEQVKTMQRNWIGKSRGMTVRFAVSDDSKQ  244
            + ++ +    +KIT YAE LL+DL+ ++ WPE +K MQRNWIGKS G  V F V D  K+
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  245  GLEGDYANFLQVYTTRPDTLMGATYVavaaehplataaaaDKPELQAFIAECKAGSVAEA  304
                     + V+TTRPDTL GATY         A   A   ++    +A+ K  +   +
Sbjct  243  ---------FTVFTTRPDTLFGATYA--VLAPEHALVDAITTSDQAEAVADYKRQASLKS  291

Query  305  DMA----TMEKKGVPTGRYVVNPLNGDKLEVWIANYVLWGYGDGAVMAVPAHDERDFEFA  360
            D+A    + EK GV TG Y +NP+NG  + VWIA+YVL +YG GA+MAVPAHDERD EFA
Sbjct  292  DLARTDLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFA  351

Query  361  TKYNLPKKQVI---AVGDNAFDENQWQEWYGDKENGVLVNSGDLDGLDFQTAFDAVAAKL  417
             ++NL    V+    V + AF            E+G+ +NS+ LDGLD  +A+  +   L
Sbjct  352  KQFNLDIIPVLEGGNVEEAAF-----------TEDGLHINSDFLDGLDKASAIAKMVEWL  400

Query  418  QNQGAGEPKTQYRLRDWGISRQRYWGCPIPIVHCEQCGDVPVPADQLPVVLP--ENVVPD  475
            + +G G+ +  YRLRDW +SRQRYWG PIPI+H E+    +VP  +LP+VLP   ++ P 
Sbjct  401  EAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPS  460

Query  476  GMG-SPLAKMPEFYETACPCCGGAAKRETDTMDTFMESSWYFFRYMSPKFSDGMVDPAAA  534
            G G SPLA++ +  E +    G  ++RET+TM     SSWY++RY+ P  ++ + D    
Sbjct  461  GTGESPLANVTDWLEVTRE-DGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELL  519

Query  535  KYWGAVDQYIGGIEHAILHLLYARFFTKLMRDEGLVNVDEPFERLLTQGMVVCETYYREN  594
            K W +VD Y+GG EHA+LHLLYARF  K++ D G+V   EPF++L+ QGM++  +Y   +
Sbjct  520  KQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY--RD  577

Query  595  DKGGKDWINPADVELTFDDKGRPISAVLKADGLPVVISGTEKMSKSKNNGVDPQELINAY  654
             +G+   +    VE       +  ++ +  +    +  +  KMSKS +N V+P+++++ Y
Sbjct  578  SRGAL--VATDKVE-------KRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQY  628

Query  655  GADTARLFMMFAAPPEQSLEWSDSGVEGAHRFLRRLWRTVYEYLKQGEAVKAFAGSQDGL  714
            GADT R++ MF +P + S+ WS+ G+EG+++FL R+ R +        + K ++  + G 
Sbjct  629  GADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLI--------TTKEITEENSG-  679

Query  715  SKELKDLRHKLHSTIAKVSDDYGRRQQFNTAIAAVMELLNQYDKTDTGGEQGRAVAQEVL  774
                  L    + T+  V+++ ++  +FNTAIA +M ++N  +K D        +  +  
Sbjct  680  -----ALDKVYNETVKAVTEQVDQM-KFNTAIAQLMVFVNAANKEDK-------LFSDYA  726

Query  775  ETAVRLLWPIVPHICETLWSEL--NGAKLWEAGWPTVDEAALVKSEIEVMVQVNGKLRGK  832
               V+L+ P+ PH+ E LW  L  +G  +    WP+ DE+ LV +++E++VQ++GK+++K
Sbjct  727  KGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAK  786

Query  833  ITvaadaskadleaaalategavkFMEGKPAKKIIVVPGRLVNIVV  878
            + VA D S+ +L+  ALA E     + GK   K+I VP +LVNIV+
Sbjct  787  LVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

1665) leuS in NC_017514


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  487 bits (1838),  Expect = 1e-138, Method: Compositional matrix adjust.
 Identities = 362/886 (41%), Positives = 534/886 (61%), Gaps = 71/886 (8%)

Query  5    YQPAAIEPAAQKKWDDARIFNVSEDASKPKYYCLSMFPYPSGK-LHMGHVRNYTIGDVLS  63
            Y+ +AIEP  Q  W D + F+ + DASKPK+Y L MFPYPSG  LH+GH   YT  D+LS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RFKLLNGFNVMQPMGWDAFGMPAENAAMKNNVAPAAWTYDNIEYMKTQLKSLGFAIDWAR  123
            RFK  +G NV++PMGWDAFG+PAE+ AM     PA  T +NI   K Q+++LGF+ DW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ETATCKPEYYRWEQWLFTKLFEKGIVYRKNGTVNWDPVDQTVLANEQVI-DGRGWRSGAL  182
            E  T  P+YY+W QW+FTKL+EKG+ Y  +  VNW     T +ANE+V+ DG + R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  IEKREIPMYYFKITDYAEELLNDLDKLEHWPEQVKTMQRNWIGKSRGMTVRFAVSDDSKQ  242
            + ++ +    +KIT YAE LL+DL+ ++ WPE +K MQRNWIGKS G  V F V D  K+
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  GLEGDYAKFLQVYTTRPDTLMGATYVavaaehplataaaaDKPELQEFIAECKAGSVAEA  302
                     + V+TTRPDTL GATY         A   A   ++  E +A+ K  +   +
Sbjct  243  ---------FTVFTTRPDTLFGATYA--VLAPEHALVDAITTSDQAEAVADYKRQASLKS  291

Query  303  DMA----TMEKKGVPTGRYVVNPLNGDKLEVWIANYVLWGYGDGAVMAVPAHDERDFEFA  358
            D+A    + EK GV TG Y +NP+NG  + VWIA+YVL +YG GA+MAVPAHDERD EFA
Sbjct  292  DLARTDLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFA  351

Query  359  TKYNLPKKQVI---AVGDNAFDENQWQEWYGDKENGVLVNSGDLDGLDFQTAFDAVAAKL  415
             ++NL    V+    V + AF            E+G+ +NS+ LDGLD  +A+  +   L
Sbjct  352  KQFNLDIIPVLEGGNVEEAAF-----------TEDGLHINSDFLDGLDKASAIAKMVEWL  400

Query  416  QSQGAGEPKTQYRLRDWGISRQRYWGCPIPIVHCEQCGDVPVPADQLPVVLP--ENVVPD  473
            +++G G+ +  YRLRDW +SRQRYWG PIPI+H E+    +VP  +LP+VLP   ++ P 
Sbjct  401  EAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPS  460

Query  474  GMG-SPLAKMPEFYETACPCCGGAAKRETDTMDTFMESSWYFFRYMSPKFSDGMVDPAAA  532
            G G SPLA++ +  E +    G  ++RET+TM     SSWY++RY+ P  ++ + D    
Sbjct  461  GTGESPLANVTDWLEVTRE-DGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELL  519

Query  533  KYWGAVDQYIGGIEHAILHLLYARFFTKLMRDEGLVNVDEPFERLLTQGMVVCETYYREN  592
            K W +VD Y+GG EHA+LHLLYARF  K++ D G+V   EPF++L+ QGM++  +Y   +
Sbjct  520  KQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY--RD  577

Query  593  DKGGKDWINPADVELTFDDKGRPISAVLKADGLPVVISGTEKMSKSKNNGVDPQELINAY  652
             +G+   +    VE       +  ++ +  +    +  +  KMSKS +N V+P+++++ Y
Sbjct  578  SRGAL--VATDKVE-------KRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQY  628

Query  653  GADTARLFMMFAAPPEQSLEWSDSGVEGAHRFLRRLWRTVYEYLKQGEAVKAFAGSQDGL  712
            GADT R++ MF +P + S+ WS+ G+EG+++FL R    VY  +   E     +G+ D  
Sbjct  629  GADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR----VYRLITTKEITEENSGALD--  682

Query  713  SKELKDLRHKLHATTAKVSDDYGRRQQFNTAIAAVMELLNQYDKTDTGGEQGRAVAQEVL  772
                     K+   T K   +   + +FNTAIA +M ++N  +K D        +  +  
Sbjct  683  ---------KVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK-------LFSDYA  726

Query  773  ETAVRLLWPIVPHICETLWSEL--NGAKLWEAGWPTVDEAALVKSEIEVMVQVNGKLRGK  830
               V+L+ P+ PH+ E LW  L  +G  +    WP+ DE+ LV +++E++VQ++GK+++K
Sbjct  727  KGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAK  786

Query  831  ITvaadaskadleaaalategavkFMEGKPAKKIIVVPGRLVNIVV  876
            + VA D S+ +L+  ALA E     + GK   K+I VP +LVNIV+
Sbjct  787  LVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

1666) leuS in NC_017515


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  487 bits (1836),  Expect = 1e-138, Method: Compositional matrix adjust.
 Identities = 361/886 (41%), Positives = 533/886 (61%), Gaps = 71/886 (8%)

Query  7    YQPAAIEPAAQKKWDDARIFNVSEDASKPKYYCLSMFPYPSGK-LHMGHVRNYTIGDVLS  65
            Y+ +AIEP  Q  W D + F+ + DASKPK+Y L MFPYPSG  LH+GH   YT  D+LS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  66   RFKLLNGFNVMQPMGWDAFGMPAENAAMKNNVAPAAWTYDNIEYMKTQLKSLGFAIDWAR  125
            RFK  +G NV++PMGWDAFG+PAE+ AM     PA  T +NI   K Q+++LGF+ DW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  126  ETATCKPEYYRWEQWLFTKLFEKGIVYRKNGTVNWDPVDQTVLANEQVI-DGRGWRSGAL  184
            E  T  P+YY+W QW+FTKL+EKG+ Y  +  VNW     T +ANE+V+ DG + R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  185  IEKREIPMYYFKITDYAEELLNDLDKLEHWPEQVKTMQRNWIGKSRGMTVRFAVSDDSKQ  244
            + ++ +    +KIT YAE LL+DL+ ++ WPE +K MQRNWIGKS G  V F V D  K+
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  245  GLEGDYANFLQVYTTRPDTLMGATYVavaaehplataaaaGKPELQAFIAECKAGSVAEA  304
                     + V+TTRPDTL GATY         A   A   ++    +A+ K  +   +
Sbjct  243  ---------FTVFTTRPDTLFGATYA--VLAPEHALVDAITTSDQAEAVADYKRQASLKS  291

Query  305  DMA----TMEKKGVPTGRYVVNPLNGDKLEVWIANYVLWGYGDGAVMAVPAHDERDFEFA  360
            D+A    + EK GV TG Y +NP+NG  + VWIA+YVL +YG GA+MAVPAHDERD EFA
Sbjct  292  DLARTDLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFA  351

Query  361  TKYNLPKKQVI---AVGDNAFDENQWQEWYGDKENGVLVNSGDLDGLDFQTAFDAVAAKL  417
             ++NL    V+    V + AF            E+G+ +NS+ LDGLD  +A+  +   L
Sbjct  352  KQFNLDIIPVLEGGNVEEAAF-----------TEDGLHINSDFLDGLDKASAIAKMVEWL  400

Query  418  QSQGAGEPKTQYRLRDWGISRQRYWGCPIPIVHCEQCGDVPVPADQLPVVLP--ENVVPD  475
            +++G G+ +  YRLRDW +SRQRYWG PIPI+H E+    +VP  +LP+VLP   ++ P 
Sbjct  401  EAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPS  460

Query  476  GMG-SPLAKMPEFYETACPCCGGAAKRETDTMDTFMESSWYFFRYMSPKFSDGMVDPAAA  534
            G G SPLA++ +  E +    G  ++RET+TM     SSWY++RY+ P  ++ + D    
Sbjct  461  GTGESPLANVTDWLEVTRE-DGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELL  519

Query  535  KYWGAVDQYIGGIEHAILHLLYARFFTKLMRDEGLVNVDEPFERLLTQGMVVCETYYREN  594
            K W +VD Y+GG EHA+LHLLYARF  K++ D G+V   EPF++L+ QGM++  +Y   +
Sbjct  520  KQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY--RD  577

Query  595  DKGGKDWINPADVELTFDDKGRPISAVLKADGLPVVISGTEKMSKSKNNGVDPQELINAY  654
             +G+   +    VE       +  ++ +  +    +  +  KMSKS +N V+P+++++ Y
Sbjct  578  SRGAL--VATDKVE-------KRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQY  628

Query  655  GADTARLFMMFAAPPEQSLEWSDSGVEGAHRFLRRLWRTVYEYLKQGEAVKAFAGSQDGL  714
            GADT R++ MF +P + S+ WS+ G+EG+++FL R    VY  +   E     +G+ D  
Sbjct  629  GADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR----VYRLITTKEITEENSGALD--  682

Query  715  SKELKDLRHKLHATTAKVSDDYGRRQQFNTAIAAVMELLNQYDKTDTGGEQGRAVAQEVL  774
                     K+   T K   +   + +FNTAIA +M ++N  +K D        +  +  
Sbjct  683  ---------KVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK-------LFSDYA  726

Query  775  ETAVRLLWPIVPHICETLWSEL--NGAKLWEAGWPTVDEAALVKSEIEVMVQVNGKLRGK  832
               V+L+ P+ PH+ E LW  L  +G  +    WP+ DE+ LV +++E++VQ++GK+++K
Sbjct  727  KGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAK  786

Query  833  ITvaadaskadleaaalategavkFMEGKPAKKIIVVPGRLVNIVV  878
            + VA D S+ +L+  ALA E     + GK   K+I VP +LVNIV+
Sbjct  787  LVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

1667) leuS in NC_009656


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  487 bits (1838),  Expect = 1e-138, Method: Compositional matrix adjust.
 Identities = 354/880 (41%), Positives = 546/880 (63%), Gaps = 61/880 (6%)

Query  5    YQPLEIETQAQNYWKEHQSFLVRELPDKEKFYCLSMFPYPSGK-LHMGHVRNYTIGDVIS  63
            Y+   IE + Q +W ++++F     + K KFY L MFPYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYHRMQGRNVLQPMGWDAFGMPAENAAMKNNVAPAAWTYDNIAYMKSQLDSLGLAIDWTR  123
            R+ R QG+NVL+PMGWDAFG+PAE+ AM     PA  T +NIA  K Q+++LG++ DW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVTTCKPDYYRWEQWLFTRLFEKGVIYRKNGTVNWDPVDQTVLANEQVI-DGRGWRSGAL  182
            EV T  P+YY+W QW+FT+L+EKG+ Y  +  VNW     T +ANE+V+ DG + R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  IEKREIPMYYFKITAYAEELLESLDNLPGWPEQVKTMQRNWIGKSRGMEIAFPYDQASIG  242
            + ++ +    +KITAYAE LLE L+++ +WPE +K MQRNWIGKS G +++F   ++   
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTD--  240

Query  243  HAGQLKVFTTRPDTLMGATYVAVAAEHPLATQAAQNDPQLQAFIDECKRGGVAEADIA--  300
               ++ VFTTRPDTL GATY  +A+EH+L    + +D Q +A + + KR +   +D+A  
Sbjct  241  --KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSD-QAEA-VADYKRQASLKSDLART  296

Query  301  --TQEKKGLATSLFVEHPLTGDKLPVWVANYVLMNYGEGAVMAVPGHDERDFEFANKYGL  358
              ++EK G+ T+ +  +P+ G  +PVW+A+YVL +YG GA+MAVP+HDERD EFA+++ L
Sbjct  297  DLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNL  356

Query  359  PIRQVIARVEGENDFEPTVWKEWYGAKDESVRTVNSGKYDDLGYQAAFDAIGADLEAKGL  418
             I  V+   + E+           +  +++++ +NS+  D+L+  +A+  +   LEA G+
Sbjct  357  DIIPVLEGGNVEEA----------AFTEDGLH-INSDFLDGLDKASAIAKMVEWLEAEGV  405

Query  419  GQARTQFRLRDWGISRQRYWGCPIPIIHCDACGDVPVPAEQlpvvlpedvvpdGAG---S  475
            G+    +RLRDW +SRQRYWG PIPIIH +     +VP  +LP+VLP       +G   S
Sbjct  406  GNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGES  465

Query  476  PLAKMPEFYECSCPKCGQPAKRETDTMDTFVESSWYFARYACPQFEGGMLDKKAADYWLP  535
            PLA++ +  E +    G  ++RET+TM     SSWY+ RY  P+    + D      WLP
Sbjct  466  PLANVTDWLEVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLP  524

Query  536  VDQYIGGIEHAILHLLYARFFHKLMRDEGLVGSDEPFRNLLTQGMVVADTYYRTTANGGK  595
            VD Y+GG EHA+LHLLYARF HK++ D G+V + EPF++L+ QGM+++ + YR       
Sbjct  525  VDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS-YR-------  576

Query  596  DWFNPADVEVERDAKAKVVGARLKSDGQPVEIGGTEKMSKSKNNGVDPQSMIDQYGADTC  655
               ++ +  V  D   K  G+ +  +       +  KMSKS +N V+P+ +++QYGADT 
Sbjct  577  ---DSRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTL  633

Query  656  RLFMMFASPPDMSLEWSDAGVEGANRFLRRVWRLAHA-HVSAGLPGALDGASLSDAQKQV  714
            R++ MF +P D S+ WS+ G+EG+ +FL RV RL  + +++   +GALD           
Sbjct  634  RVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALD-----------  682

Query  715  RRAIHLAIRQASQDVGQHHKFNTAIAAVMTLMNVLEKAPSQDAQDRALLQEGLETVVLLL  774
             +  + +++  +++V ++ KFNTAIA +M ++N  +K       +  L+ +     V L+
Sbjct  683  -KVYNETVKAVTEQV-DQMKFNTAIAQLMVFVNAANK-------EDKLFSDYAKGFVQLI  733

Query  775  APITPHICHVLWEQLGHAEAVID-ARWPVVDESAlvqdtlqlvvqvNGKLRGHIDVAASA  833
            AP++PH+ + LW+ L  +   I    WP  DES LV++ +++VVQ++GK+++ + VA   
Sbjct  734  APFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDL  793

Query  834  SREDVEAAARANENVLRFTEGLSIRKVIVVPGKLVNIVAN  873
            SRE+++  A ANE+V     G  I KVI VP KLVNIV +
Sbjct  794  SREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

1668) leuS in NC_012814


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  487 bits (1836),  Expect = 2e-138, Method: Compositional matrix adjust.
 Identities = 332/752 (45%), Positives = 481/752 (64%), Gaps = 71/752 (9%)

Query  212  LAYISKSPVNWCPGLGTVLANEEVTAEGRSERGNFPVFQRELRQWSMRITAYGHRLIEDL  271
            LAY +  PVNW   LGT +ANEEV ++G SERG +PV ++ +RQW ++ITAY++RL+EDL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  272  DSIDWPEKVKLMQRNWIGESHGASVHFKVPVDGEMADMEIYTTRPDTLFGATFCVVSPEH  331
            + +DWPE +K MQRNWIG S GA+V FKV   +   D  ++TTRPDTLFGAT+ V++PEH
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDK--DFTVFTTRPDTLFGATYAVLAPEH  265

Query  332  PMLEHVPQSWPEGVDPAWTGGYATPSEAVSAYRELAEAKTAADRVADNGEKTGLFTGLYA  391
            ++++ +  S                +EAV+ Y+  A  K+   R     EKTG+ TG YA
Sbjct  266  ALVDAITTS--------------DQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYA  311

Query  392  INPITGAKLPVFTADYVLMDYGTGAIMAVPGGDQRDYDFAVKYGLPVIYTVAPLPDSGDD  451
            INP+ G  +PV  ADYVL  YGTGAIMAVP+ D+RD +FA ++ L +I    P+ ++G+ 
Sbjct  312  INPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDII----PVLEGGN-  366

Query  452  LANYEGTAPFVSHDGIVINSAVDATWARGDALCLDGMRVDDAIAAVTTWLEEAQVGKGAT  511
                   A+F ++DG+ INS             LDG+    AIA +  WLE   VG+   
Sbjct  367  ----VEEAAF-TEDGLHINSD-----------FLDGLDKASAIAKMVEWLEAEGVGNENV  410

Query  512  SYRLRDWLFSRQRYWGEPFPIVYDEHEVPHLVPDSMLPINLPDVPDYSPKTFDPEDSQSS  571
            +YRLRDWLFSRQRYWGEP+PI+  E+  +  VP+S LP+ LP   D  P         ++
Sbjct  411  TYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPS--------GT  462

Query  572  PEAPLSRNEDWVNVTLDLGDGPKTYHHDTNTMPNWAGSCWYYMRYLNPHDTEHMVERDEY  631
             E+PL+   DW++VT +  DG K  +++TNTMP+WAGS WYY+RY++PH+TE + + +  
Sbjct  463  GESPLANVTDWLEVTRE--DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELL  519

Query  632  DYWMGPKHSPAAGQAGGVDLYVGGVEHAVLHLLYSRFWHKILFDLGYVDSFEPFHKLFNQ  691
              W+             VD+YVGG EHAVLHLLY+RFWHK+L+DLG V + EPF+KLFNQ
Sbjct  520  KQWL------------PVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQ  567

Query  692  GMIQAYAYTDDRGQYVPAEDVQESEVDGKTVYTYEGEPVNREFGKMGKSLKNIVTPDYMY  751
            GMI + +Y D RG  V+++ V+    DG       GE +++  +KM+KSLKN+V PD + 
Sbjct  568  GMILGTSYRDSRGALVATDKVEKR--DGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVV  625

Query  752  DHYGADTFRLYEMSMGPLDESRPWNTRNVVGGMRFLQRLWRNVIDENTGEVTVTDDAMDE  811
            ++YGADT+R+YEM MGPLD S +W+   + G+ +FL+R+ R +   +  E     +A+D 
Sbjct  626  EQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITE--ENSGALD-  682

Query  812  RTLKLLNNTIAEVTGEMEAMRPNTAIAKLIVLNNHLTGMNGVPRAAVEPLVLMVAPIAPH  871
               K+ N+T+  VT +++ M+ NTAIA+L+V+ N     + +       +V ++AP+APH
Sbjct  683  ---KVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPH  739

Query  872  IAEELWNRL-GHDESLAHHPWPQADERYVGQDTVTAVVQIKGKVRAKLEVSADIDPDELE  930
            ++EELW+ L + +ES++  PWP  DE  + ++ V  VVQIKGKV+AKL V+ D+  +EL+
Sbjct  740  LGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQ  799

Query  931  KMAL--EAVAERLGGKPPRKVIVKAPKIVSIV  960
             +AL  E V   ++GK   KVI  + K+V+IV
Sbjct  800  EVALANEKVQAEIAGKDIIKVIAVPNKLVNIV  831


 Score =  137 bits (504),  Expect = 3e-33, Method: Compositional matrix adjust.
 Identities = 76/149 (52%), Positives = 105/149 (71%), Gaps = 12/149 (8%)

Query  5    IEEKWQDIWESEGTFWAANVSGELTDSKGRHADGRQSFFAMDMFPYPSGKGLHVGHPLGY  64
            IE KWQ +W  + TF            K     ++  F+A+DMFPYPSG GLHVGHP GY
Sbjct  9    IEPKWQAFWADNHTF------------KTGTDASKPKFYALDMFPYPSGAGLHVGHPEGY  56

Query  65   LATDVVSRYHRMKGENVLHAMGYDAFGLPAEQYAVQTGQHPRITTEQNIANMRRQLRRMG  124
             ATD++SR+ R +G+NVLH+MG DAFGLPAEQYA++TG++P   T +NIAN +RQ+  +G
Sbjct  57   TATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALG  116

Query  125  LSFDDRRSFATIEPEYVRWTQWIFSRIYD  153
            +S+D  R   T +P+Y +WTQWIF+++Y+
Sbjct  117  FSYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1669) leuS in NC_012815


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  487 bits (1836),  Expect = 2e-138, Method: Compositional matrix adjust.
 Identities = 332/752 (45%), Positives = 481/752 (64%), Gaps = 71/752 (9%)

Query  212  LAYISKSPVNWCPGLGTVLANEEVTAEGRSERGNFPVFQRELRQWSMRITAYGHRLIEDL  271
            LAY +  PVNW   LGT +ANEEV ++G SERG +PV ++ +RQW ++ITAY++RL+EDL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  272  DSIDWPEKVKLMQRNWIGESHGASVHFKVPVDGEMADMEIYTTRPDTLFGATFCVVSPEH  331
            + +DWPE +K MQRNWIG S GA+V FKV   +   D  ++TTRPDTLFGAT+ V++PEH
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDK--DFTVFTTRPDTLFGATYAVLAPEH  265

Query  332  PMLEHVPQSWPEGVDPAWTGGYATPSEAVSAYRELAEAKTAADRVADNGEKTGLFTGLYA  391
            ++++ +  S                +EAV+ Y+  A  K+   R     EKTG+ TG YA
Sbjct  266  ALVDAITTS--------------DQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYA  311

Query  392  INPITGAKLPVFTADYVLMDYGTGAIMAVPGGDQRDYDFAVKYGLPVIYTVAPLPDSGDD  451
            INP+ G  +PV  ADYVL  YGTGAIMAVP+ D+RD +FA ++ L +I    P+ ++G+ 
Sbjct  312  INPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDII----PVLEGGN-  366

Query  452  LANYEGTAPFVSHDGIVINSAVDATWARGDALCLDGMRVDDAIAAVTTWLEEAQVGKGAT  511
                   A+F ++DG+ INS             LDG+    AIA +  WLE   VG+   
Sbjct  367  ----VEEAAF-TEDGLHINSD-----------FLDGLDKASAIAKMVEWLEAEGVGNENV  410

Query  512  SYRLRDWLFSRQRYWGEPFPIVYDEHEVPHLVPDSMLPINLPDVPDYSPKTFDPEDSQSS  571
            +YRLRDWLFSRQRYWGEP+PI+  E+  +  VP+S LP+ LP   D  P         ++
Sbjct  411  TYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPS--------GT  462

Query  572  PEAPLSRNEDWVNVTLDLGDGPKTYHHDTNTMPNWAGSCWYYMRYLNPHDTEHMVERDEY  631
             E+PL+   DW++VT +  DG K  +++TNTMP+WAGS WYY+RY++PH+TE + + +  
Sbjct  463  GESPLANVTDWLEVTRE--DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELL  519

Query  632  DYWMGPKHSPAAGQAGGVDLYVGGVEHAVLHLLYSRFWHKILFDLGYVDSFEPFHKLFNQ  691
              W+             VD+YVGG EHAVLHLLY+RFWHK+L+DLG V + EPF+KLFNQ
Sbjct  520  KQWL------------PVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQ  567

Query  692  GMIQAYAYTDDRGQYVPAEDVQESEVDGKTVYTYEGEPVNREFGKMGKSLKNIVTPDYMY  751
            GMI + +Y D RG  V+++ V+    DG       GE +++  +KM+KSLKN+V PD + 
Sbjct  568  GMILGTSYRDSRGALVATDKVEKR--DGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVV  625

Query  752  DHYGADTFRLYEMSMGPLDESRPWNTRNVVGGMRFLQRLWRNVIDENTGEVTVTDDAMDE  811
            ++YGADT+R+YEM MGPLD S +W+   + G+ +FL+R+ R +   +  E     +A+D 
Sbjct  626  EQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITE--ENSGALD-  682

Query  812  RTLKLLNNTIAEVTGEMEAMRPNTAIAKLIVLNNHLTGMNGVPRAAVEPLVLMVAPIAPH  871
               K+ N+T+  VT +++ M+ NTAIA+L+V+ N     + +       +V ++AP+APH
Sbjct  683  ---KVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPH  739

Query  872  IAEELWNRL-GHDESLAHHPWPQADERYVGQDTVTAVVQIKGKVRAKLEVSADIDPDELE  930
            ++EELW+ L + +ES++  PWP  DE  + ++ V  VVQIKGKV+AKL V+ D+  +EL+
Sbjct  740  LGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQ  799

Query  931  KMAL--EAVAERLGGKPPRKVIVKAPKIVSIV  960
             +AL  E V   ++GK   KVI  + K+V+IV
Sbjct  800  EVALANEKVQAEIAGKDIIKVIAVPNKLVNIV  831


 Score =  137 bits (504),  Expect = 3e-33, Method: Compositional matrix adjust.
 Identities = 76/149 (52%), Positives = 105/149 (71%), Gaps = 12/149 (8%)

Query  5    IEEKWQDIWESEGTFWAANVSGELTDSKGRHADGRQSFFAMDMFPYPSGKGLHVGHPLGY  64
            IE KWQ +W  + TF            K     ++  F+A+DMFPYPSG GLHVGHP GY
Sbjct  9    IEPKWQAFWADNHTF------------KTGTDASKPKFYALDMFPYPSGAGLHVGHPEGY  56

Query  65   LATDVVSRYHRMKGENVLHAMGYDAFGLPAEQYAVQTGQHPRITTEQNIANMRRQLRRMG  124
             ATD++SR+ R +G+NVLH+MG DAFGLPAEQYA++TG++P   T +NIAN +RQ+  +G
Sbjct  57   TATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALG  116

Query  125  LSFDDRRSFATIEPEYVRWTQWIFSRIYD  153
            +S+D  R   T +P+Y +WTQWIF+++Y+
Sbjct  117  FSYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1670) leuS in NC_017217


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  487 bits (1836),  Expect = 2e-138, Method: Compositional matrix adjust.
 Identities = 332/752 (45%), Positives = 481/752 (64%), Gaps = 71/752 (9%)

Query  212  LAYISKSPVNWCPGLGTVLANEEVTAEGRSERGNFPVFQRELRQWSMRITAYGHRLIEDL  271
            LAY +  PVNW   LGT +ANEEV ++G SERG +PV ++ +RQW ++ITAY++RL+EDL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  272  DSIDWPEKVKLMQRNWIGESHGASVHFKVPVDGEMADMEIYTTRPDTLFGATFCVVSPEH  331
            + +DWPE +K MQRNWIG S GA+V FKV   +   D  ++TTRPDTLFGAT+ V++PEH
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDK--DFTVFTTRPDTLFGATYAVLAPEH  265

Query  332  PMLEHVPQSWPEGVDPAWTGGYATPSEAVSAYRELAEAKTAADRVADNGEKTGLFTGLYA  391
            ++++ +  S                +EAV+ Y+  A  K+   R     EKTG+ TG YA
Sbjct  266  ALVDAITTS--------------DQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYA  311

Query  392  INPITGAKLPVFTADYVLMDYGTGAIMAVPGGDQRDYDFAVKYGLPVIYTVAPLPDSGDD  451
            INP+ G  +PV  ADYVL  YGTGAIMAVP+ D+RD +FA ++ L +I    P+ ++G+ 
Sbjct  312  INPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDII----PVLEGGN-  366

Query  452  LANYEGTAPFVSHDGIVINSAVDATWARGDALCLDGMRVDDAIAAVTTWLEEAQVGKGAT  511
                   A+F ++DG+ INS             LDG+    AIA +  WLE   VG+   
Sbjct  367  ----VEEAAF-TEDGLHINSD-----------FLDGLDKASAIAKMVEWLEAEGVGNENV  410

Query  512  SYRLRDWLFSRQRYWGEPFPIVYDEHEVPHLVPDSMLPINLPDVPDYSPKTFDPEDSQSS  571
            +YRLRDWLFSRQRYWGEP+PI+  E+  +  VP+S LP+ LP   D  P         ++
Sbjct  411  TYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPS--------GT  462

Query  572  PEAPLSRNEDWVNVTLDLGDGPKTYHHDTNTMPNWAGSCWYYMRYLNPHDTEHMVERDEY  631
             E+PL+   DW++VT +  DG K  +++TNTMP+WAGS WYY+RY++PH+TE + + +  
Sbjct  463  GESPLANVTDWLEVTRE--DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELL  519

Query  632  DYWMGPKHSPAAGQAGGVDLYVGGVEHAVLHLLYSRFWHKILFDLGYVDSFEPFHKLFNQ  691
              W+             VD+YVGG EHAVLHLLY+RFWHK+L+DLG V + EPF+KLFNQ
Sbjct  520  KQWL------------PVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQ  567

Query  692  GMIQAYAYTDDRGQYVPAEDVQESEVDGKTVYTYEGEPVNREFGKMGKSLKNIVTPDYMY  751
            GMI + +Y D RG  V+++ V+    DG       GE +++  +KM+KSLKN+V PD + 
Sbjct  568  GMILGTSYRDSRGALVATDKVEKR--DGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVV  625

Query  752  DHYGADTFRLYEMSMGPLDESRPWNTRNVVGGMRFLQRLWRNVIDENTGEVTVTDDAMDE  811
            ++YGADT+R+YEM MGPLD S +W+   + G+ +FL+R+ R +   +  E     +A+D 
Sbjct  626  EQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITE--ENSGALD-  682

Query  812  RTLKLLNNTIAEVTGEMEAMRPNTAIAKLIVLNNHLTGMNGVPRAAVEPLVLMVAPIAPH  871
               K+ N+T+  VT +++ M+ NTAIA+L+V+ N     + +       +V ++AP+APH
Sbjct  683  ---KVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPH  739

Query  872  IAEELWNRL-GHDESLAHHPWPQADERYVGQDTVTAVVQIKGKVRAKLEVSADIDPDELE  930
            ++EELW+ L + +ES++  PWP  DE  + ++ V  VVQIKGKV+AKL V+ D+  +EL+
Sbjct  740  LGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQ  799

Query  931  KMAL--EAVAERLGGKPPRKVIVKAPKIVSIV  960
             +AL  E V   ++GK   KVI  + K+V+IV
Sbjct  800  EVALANEKVQAEIAGKDIIKVIAVPNKLVNIV  831


 Score =  137 bits (504),  Expect = 3e-33, Method: Compositional matrix adjust.
 Identities = 76/149 (52%), Positives = 105/149 (71%), Gaps = 12/149 (8%)

Query  5    IEEKWQDIWESEGTFWAANVSGELTDSKGRHADGRQSFFAMDMFPYPSGKGLHVGHPLGY  64
            IE KWQ +W  + TF            K     ++  F+A+DMFPYPSG GLHVGHP GY
Sbjct  9    IEPKWQAFWADNHTF------------KTGTDASKPKFYALDMFPYPSGAGLHVGHPEGY  56

Query  65   LATDVVSRYHRMKGENVLHAMGYDAFGLPAEQYAVQTGQHPRITTEQNIANMRRQLRRMG  124
             ATD++SR+ R +G+NVLH+MG DAFGLPAEQYA++TG++P   T +NIAN +RQ+  +G
Sbjct  57   TATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALG  116

Query  125  LSFDDRRSFATIEPEYVRWTQWIFSRIYD  153
            +S+D  R   T +P+Y +WTQWIF+++Y+
Sbjct  117  FSYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1671) LeuS in NC_015738


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  486 bits (1834),  Expect = 2e-138, Method: Compositional matrix adjust.
 Identities = 360/897 (41%), Positives = 536/897 (60%), Gaps = 104/897 (11%)

Query  1    MKPYNPHEIEPRWQKEWADTDLYKVTEDASKPKKYVLEMFPYPSG-DIHMGHVRNYTIGD  59
            M  Y+   IEP+WQ  WAD + +K   DASKPK Y L+MFPYPSG ++H+GH   YT  D
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  60   VIARYSKMRGFDVLHPMGWDAFGLPAENAAIKHNSHPAKWTYANIDTQKASFKRMGFSYD  119
            +++R+ + +G +VLHPMGWDAFGLPAE+ A+   ++PA  T  NI   K  ++ +GFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  120  WDRTVVACDSEYYRWGQWIFLQFWKRGLVERRNSPVNWCPNCATVLANEQV-TEGECWRC  178
            WDR V + D++YY+W QWIF ++  +GL    + PVNW  + +T +ANE+V  +G   R 
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERG  180

Query  179  HGAVEKRDLTQWYFKITDYAQEllddldqldGWPERVKQMQANWIGRSEGAEVDFVLCDP  238
              +V ++ + QW +KIT YA E L +  +  +WPE +K+MQ NWIG+S GA+V F + D 
Sbjct  181  GYPVVRKPMRQWMLKITAYA-ERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDT  239

Query  239  DGEAPTNPTEADIITVFTTRPDTLFGCSFFLLAPEYPGLMDLVEGTEYENAVRDVVEQAS  298
            D +          +TVFTTRPDTLFG ++ +LAPE  +L+D +  ++  +AV D   QAS
Sbjct  240  DKD----------FTVFTTRPDTLFGATYAVLAPE-HALVDAITTSDQAEAVADYKRQAS  288

Query  299  KVSAVERAQGDREKHGAFTGRYMVNPINGEKVPVWVADYIVSDYGTGAVMAVPCGDQRDF  358
              S + R++  +EK G  TG Y +NP+NG  +PVW+ADY+++ YGTGA+MAVP  D+RD 
Sbjct  289  LKSDLARTDLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDW  348

Query  359  EFARKYDLPIIPIILGEDDPLYPQLNGVQERVVTTVDWDHAYDAEGVLVQSGKYTGMTGG  418
            EFA++++L IIP++ G +                 V+ + A+  +G+ ++S+   G+   
Sbjct  349  EFAKQFNLDIIPVLEGGN-----------------VE-EAAFTEDGLHINSDFLDGL---  387

Query  419  KRSPAVDAIIGDLEASGKGRKKVEFRLRDWLISRQRYWGNPIPAIHCPECGLVPVPESDL  478
             +++A+  ++  LEA G G  +V +RLRDWL+SRQRYWG+PIP IH  +    +VPES+L
Sbjct  388  DKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESEL  447

Query  479  PVRLPEDIDLAAGETLATHEAFVNT---TCPVCGGPAKRETDTMDTFTCSSWYYLRYTDP  535
            P+ LP   D+ ++ T  +  A V          G  ++RET+TM   + SSWYYLRY DP
Sbjct  448  PLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDP  507

Query  536  HNDELPFAPEKANRWLPVDQYIGGIEHAILHLLYSRFFTKVLRDLGQVDFDEPFANLLCQ  595
            HN E     E  ++WLPVD Y+GG EHA+LHLLY+RF  KVL DLG V   EPF +L+ Q
Sbjct  508  HNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQ  567

Query  596  GMV-----KDEHG----------------------------ETMSKSKGNVIAPEDMIAE  622
            GM+     +D +G                              MSKS  NV+ P+D++ +
Sbjct  568  GMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQ  627

Query  623  YGADAVRAYILFMAPPDKDLLWDEGGLAGIYKFMNRAWRIVNDLMGVAGDETLYQEGATE  682
            YGAD++R Y +FM+P D  + W E GL G  KF++R  R++                +T 
Sbjct  628  YGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLI----------------TTK  671

Query  683  EQGIEALKTLVRERHRVVGKVVDDFDRNNFNTAIAAIMELTNAASDYLRKCSLEERAACE  742
            E   E   +L +  +  V  V ++ D+ +FNTAIA +M + NAA+              E
Sbjct  672  EITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANK-------------E  718

Query  743  GSRFIDPEVAEVIVKLMAPIAPHWAEELWHDVLGREGSVHTQPWPEFNPEQAKADEVELA  802
            +  F  ++ A  +V+L+AP+APH +EELW+ + +   S+   PWP ++  +   ++VE+ 
Sbjct  719  DKLF--SDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIV  776

Query  803  VQVNGKVKAKIMVAADAPEDDVkavglaaveaalagk--DvkkvvvvPGRLVNIVAK  857
            VQ++GKVKAK++VA D + ++++ V+LA           D+ KV+ VP +LVNIV K
Sbjct  777  VQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

1672) leuS in NC_017513


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  486 bits (1833),  Expect = 2e-138, Method: Compositional matrix adjust.
 Identities = 361/886 (41%), Positives = 533/886 (61%), Gaps = 71/886 (8%)

Query  5    YQPAAIEPAAQKKWDDARIFNVSEDASKPKYYCLSMFPYPSGK-LHMGHVRNYTIGDVLS  63
            Y+ +AIEP  Q  W D + F+ + DASKPK+Y L MFPYPSG  LH+GH   YT  D+LS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RFKLLNGFNVMQPMGWDAFGMPAENAAMKNNVAPAAWTYDNIEYMKTQLKSLGFAIDWAR  123
            RFK  +G NV++PMGWDAFG+PAE+ AM     PA  T +NI   K Q+++LGF+ DW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ETATCKPEYYRWEQWLFTKLFEKGIVYRKNGTVNWDPVDQTVLANEQVI-DGRGWRSGAL  182
            E  T  P+YY+W QW+FTKL+EKG+ Y  +  VNW     T +ANE+V+ DG + R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  IEKREIPMYYFKITDYAEELLNDLDKLEHWPEQVKTMQRNWIGKSRGMTVRFAVSDDSKQ  242
            + ++ +    +KIT YAE LL+DL+ ++ WPE +K MQRNWIGKS G  V F V D  K+
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  GLEGDYAKFLQVYTTRPDTLMGATYVavaaehplaaaaaaDKPELQAFIAECKAGSVAEA  302
                     + V+TTRPDTL GATY         A   A   ++    +A+ K  +   +
Sbjct  243  ---------FTVFTTRPDTLFGATYA--VLAPEHALVDAITTSDQAEAVADYKRQASLKS  291

Query  303  DMA----TMEKKGVPTGRYVVNPLNGDKLEVWIANYVLWGYGDGAVMAVPAHDERDFEFA  358
            D+A    + EK GV TG Y +NP+NG  + VWIA+YVL +YG GA+MAVPAHDERD EFA
Sbjct  292  DLARTDLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFA  351

Query  359  AKYNLPKKQVI---AVGDNAFDANRWQEWYADKENGVLVNSGDLDGLDFQTAFDAVAAKL  415
             ++NL    V+    V + AF            E+G+ +NS+ LDGLD  +A+  +   L
Sbjct  352  KQFNLDIIPVLEGGNVEEAAF-----------TEDGLHINSDFLDGLDKASAIAKMVEWL  400

Query  416  QSQGAGEPKTQYRLRDWGISRQRYWGCPIPIVHCEQCGDVPVPADQLPVVLP--ENVVPD  473
            +++G G+ +  YRLRDW +SRQRYWG PIPI+H E+    +VP  +LP+VLP   ++ P 
Sbjct  401  EAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPS  460

Query  474  GMG-SPLAKMPEFYETACPCCGGAAKRETDTMDTFMESSWYFFRYMSPKFSDGMVDPAAA  532
            G G SPLA++ +  E +    G  ++RET+TM     SSWY++RY+ P  ++ + D    
Sbjct  461  GTGESPLANVTDWLEVTRE-DGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELL  519

Query  533  KYWGAVDQYIGGIEHAILHLLYARFFTKLMRDEGLVNVDEPFERLLTQGMVVCETYYREN  592
            K W +VD Y+GG EHA+LHLLYARF  K++ D G+V   EPF++L+ QGM++  +Y   +
Sbjct  520  KQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY--RD  577

Query  593  DKGGKDWINPADVELTFDDKGRPISAVLKADGLPVVISGTEKMSKSKNNGVDPQELINAY  652
             +G+   +    VE       +  ++ +  +    +  +  KMSKS +N V+P+++++ Y
Sbjct  578  SRGAL--VATDKVE-------KRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQY  628

Query  653  GADTARLFMMFAAPPEQSLEWSDSGVEGAHRFLRRLWRTVYEYLKQGEAVKAFAGSQDGL  712
            GADT R++ MF +P + S+ WS+ G+EG+++FL R    VY  +   E     +G+ D  
Sbjct  629  GADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR----VYRLITTKEITEENSGALD--  682

Query  713  SKELKDLRHKLHATTAKVSDDYGRRQQFNTAIAAVMELLNQYDKTDTGGEQGRAVAQEVL  772
                     K+   T K   +   + +FNTAIA +M ++N  +K D        +  +  
Sbjct  683  ---------KVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK-------LFSDYA  726

Query  773  ETAVRLLWPIVPHICETLWSEL--NGAKLWEAGWPTVDEAALVKSEIEVMVQVNGKLRGK  830
               V+L+ P+ PH+ E LW  L  +G  +    WP+ DE+ LV +++E++VQ++GK+++K
Sbjct  727  KGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAK  786

Query  831  ITvaadaskadleaaalategavkFMEGKPAKKIIVVPGRLVNIVV  876
            + VA D S+ +L+  ALA E     + GK   K+I VP +LVNIV+
Sbjct  787  LVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

1673) leuS in NC_018028


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  486 bits (1834),  Expect = 2e-138, Method: Compositional matrix adjust.
 Identities = 357/875 (41%), Positives = 548/875 (63%), Gaps = 56/875 (6%)

Query  5    YQPREIEAAAQSHWDAQKSFEVSEQPGKDTFYCLSMFPYPSGK-LHMGHVRNYTIGDVIA  63
            Y+   IE+  Q+ W  + +F  + +++K  FY L MFPYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMQGKNVLQPMGWDAFGMPAENAAMKNQVAPAKWTYENIAYMKAQLKSLGLAVDWTR  123
            R++R QG NVL+PMGWDAFG+PAE+ AM     PA  T ENIA  K Q+++LG++ DW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVTTCKPDYYRWEQWLFTRLYEKGVIYRKNGTVNWDPVDQTVLANEQVI-DGRGWRSGAL  182
            EV T  P+YY+W QW+FT+LYEKG+ Y  +  VNW     T +ANE+V+ DG + R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  IEKREIPMYYFKITAYAdellesldeldGWPEQVKTMQRNWIGKSRGMEISFPYDVASIG  242
            + ++ +    +KITAYA E L    E  +WPE +K MQRNWIGKS G +++F       +
Sbjct  184  VVRKPMRQWMLKITAYA-ERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTF----KVKD  238

Query  243  SEGVMKVFTTRPDTLMGATYVAVAAEHPLATLAAQNNPELQAFIDECKRGGVAEADIA--  300
            ++    VFTTRPDTL GATY  +A+EH+L  + A   ++    + + KR +   +D+A  
Sbjct  239  TDKDFTVFTTRPDTLFGATYAVLAPEHAL--VDAITTSDQAEAVADYKRQASLKSDLART  296

Query  301  --TQEKKGLATSLRVQHPLTGELLPVWVANYVLMNYGEGAVMAVPAHDERDFEFASKYDL  358
              ++EK G+ T+    +P+ G  +PVW+A+YVL +YG GA+MAVPAHDERD EFA +++L
Sbjct  297  DLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNL  356

Query  359  PIKPVVRTSAGDQTPAPWQDAYGEHGELINSgifdgldfdgafdaiEVALQKKGLGQART  418
             I PV+  +  +++      A+ E+G  INS+++DGLD  +A+  +   L+  G+G+   
Sbjct  357  DIIPVLEGGNVEEA------AFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENV  410

Query  419  QFRLRDWGISRQRYWGCPIPIIHCDSCGDVAVPEDQlpvvlpedvvpdGAG---SPLAHM  475
             +RLRDW +SRQRYWG PIPIIH +     AVPE +LP+VLP       +G   SPLA++
Sbjct  411  TYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANV  470

Query  476  PEFYECSCPKCGAPAKRETDTMDTFVESSWYFARYASPNYEQGMVDPAAANHWLPVDQYI  535
             +  E +    G  ++RET+TM     SSWY+ RY  P+  + + D    ++WLPVD Y+
Sbjct  471  TDWLEVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYV  529

Query  536  GGIEHAILHLLYARFFHKLMRDEGLVSSNEPFKNLLTQGMVVADTYYRTLENGGKDWFNP  595
            GG EHA+LHLLYARF HK++ D G+V+++EPF++L+ QGM+++ + YR          ++
Sbjct  530  GGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS-YR----------DS  578

Query  596  ADVIVERDAKAKIIGAKLASDGLPVEIGGTEKMSKSKNNGVDPQAMIDAYGADTCRLFMM  655
             + +V  D   K  G+ +  +       +  KMSKS +N V+P+ +++ YGADT R++ M
Sbjct  579  RGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEM  638

Query  656  FASPPDMSLEWSDSGVEGASRFLRRVWRLAHA-HVSAGVAGTLDTASLSDEQKAVRRAIH  714
            F +P D S+ WS+ G+EG+ +FL RV RL  + +++   +G+LD            +  +
Sbjct  639  FMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALD------------KVYN  686

Query  715  LAIKQASVDVGQHHKFNTAIAQVMTLMNVLEKAATASEQDRALLQEGLETVALLLAPITP  774
             ++K  + +V ++ KFNTAIAQ+M ++N       A++++  L+ +       L+AP++P
Sbjct  687  ETVKAVTEQV-DQMKFNTAIAQLMVFVN-------AANKEDKLFSDYAKGFVQLIAPFAP  738

Query  775  HISHELWQRLGKQGAIID-AQWPKVDESALVQDSLTLVVQVNGKLRGQIevpaaatreev  833
            H+++ELWQ L   G  I    WP  DES LV++ + +VVQ++GK+++++ V+   +REE+
Sbjct  739  HLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREEL  798

Query  834  eaaarGNENVLRFTVGLTIRKVIVVPGKLVNIVAN  868
            +  A +NE+V     G  I KVI VP KLVNIV +
Sbjct  799  QEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

1674) SCATT_16200 in NC_017586


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  486 bits (1833),  Expect = 3e-138, Method: Compositional matrix adjust.
 Identities = 350/740 (48%), Positives = 483/740 (66%), Gaps = 59/740 (7%)

Query  221  LAYASESPVNWCPGLGTVLANEEVTADGRSERGNFPVFKAKLRQWMMRITAYADRLLEDL  280
            LAY +E PVNW   LGT +ANEEV +DG SERG +PV +  +RQWM++ITAYA+RLLEDL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  281  DVLDWPEAIKLQQRNWIGRSEGARIDFPVHLQGDGDATITVFSTRQDTLFGATYMVLAPE  340
            + +DWPE+IK  QRNWIG+S GA + F V    D D  +TVF+TR DTLFGATY VLAPE
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVK---DTDKDFTVFTTRPDTLFGATYAVLAPE  264

Query  341  HELVDGIVPAVWPEGTHEVWTGGHATPaeavaayrkqaaaKSDVERQADAKEKTGVFTGA  400
            H LVD+I  +  +E+  +               Y++QA+ KSD+ R   AKEKTGV TG+
Sbjct  265  HALVDAITTSDQAEAVAD---------------YKRQASLKSDLARTDLAKEKTGVWTGS  309

Query  401  YAVNPVNGEKVPVFIADYVLMGYGTGAIMAVPAHDSRDFAFARAFELPMRCVVEPSDGRG  460
            YA+NPVNG  +PV IADYVL +YGTGAIMAVPAHD RD  FA+ F+L +  V+E ++   
Sbjct  310  YAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVE-  368

Query  461  QDPARWDDSFDSYDARIVNSSGAEISLDGLTVPEAKARMTQWLTERGIGEGTVNYRLRDW  520
                  + +F   + +I +       LDGL  + A A+M +WL   G+G+  V YRLRDW
Sbjct  369  ------EAAFTEDGLHINSD-----FLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDW  417

Query  521  LFSRQRYWGEPFPIVYDEQGVAHALPDSMLPVELPEVDDYRPRTFDPDDADTSPETPLSR  580
            LFSRQRYWGEP+PI+  E+G + A+P+S LP+ LP   D RP          + E+PL+ 
Sbjct  418  LFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLAN  469

Query  581  NEDWvdvvldlgdgPKRYRRETNTMPNWAGSCWYELRYLDPDNPDRLVDPQVESYWMGPR  640
              DW++V  + G      RRETNTMP+WAGS WY LRY+DP+N ++L D ++   W+   
Sbjct  470  VTDWLEVTREDGVKG---RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWL---  523

Query  641  EGQPSGGVDLYVGGSEHAVLHLLYARFWHKVLHDLGHVSSYEPYQRLFNQGMITAYVYRD  700
                   VD+YVGG+EHAVLHLLYARFWHKVL DLG V++ EP+Q+LFNQGMI +  YRD
Sbjct  524  ------PVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRD  577

Query  701  SRGFPVPAAEVEEREDGFYH--QGEKVRREHGKMGKSLKNAVTPDEICAEYGADTLRLYE  758
            SRG  V++  VE R+++F+H   GE + +  +KM+KSLKN V PD++  +YGADTLR+YE
Sbjct  578  SRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYE  637

Query  759  MAMGPLDVSRPWDTRAVVGSYRFLQRLWRNVVDEATGEATVVDQEPDEETLRALHKAIDG  818
            M MGPLD S +W   ++ GS +FL+R+ R +      E      +      +  + ++ +
Sbjct  638  MFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALD------KVYNETVKA  691

Query  819  IRTDMAALRFNTAIAKATELNNHLTKLPRVPRTVAETMVLLVAPLAPHIAEELWRRL-GH  877
            +  ++  ++FNTAIA+   + N   K  ++    A   V L+AP+APH++EELW+ L + 
Sbjct  692  VTEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTAS  751

Query  878  ESSLayadypvadpayvvdETVTCVVQIKGKVRARLEVPPAITeaeleklaladatvvaa  937
              S++Y   P  D + +V++ V  VVQIKGKV+A+L V+  ++  EL+ +ALA+  V A 
Sbjct  752  GESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAE  811

Query  938  lggaEIRKVIVRAPKLVNIV  957
            ++G +I KVI  + KLVNIV
Sbjct  812  IAGKDIIKVIAVPNKLVNIV  831


 Score =  134 bits (491),  Expect = 3e-32, Method: Compositional matrix adjust.
 Identities = 73/151 (49%), Positives = 102/151 (68%), Gaps = 11/151 (7%)

Query  22   AQIEARWQDLWEREGTFQAPNPGGGDLGGPAEVVERPKKFFMDMFPYPSGAGLHVGHPLG  81
            + IE++WQ +W  + TF++   ++           +PK + +DMFPYPSGAGLHVGHP G
Sbjct  7    TAIEPKWQAFWADNHTFKTGTDAS-----------KPKFYALDMFPYPSGAGLHVGHPEG  55

Query  82   YIATDVYARYHRMTGHNVLHTLGFDAFGLPAEQYAVQTGTHPRITTEANITTMRRQLRRL  141
            Y ATD+ +R+ R  GHNVLH +G DAFGLPAEQYA++TG +P   T  NI+  +RQ+  L
Sbjct  56   YTATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINAL  115

Query  142  GLGHDQRRSFATIDPAYYRWTQWIFLQIFNS  172
            G++ D  R   T DP YY+WTQWIF ++++ 
Sbjct  116  GFSYDWDREVNTTDPNYYKWTQWIFTKLYEK  146

1675) leuS in NC_016111


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  486 bits (1833),  Expect = 3e-138, Method: Compositional matrix adjust.
 Identities = 350/740 (48%), Positives = 483/740 (66%), Gaps = 59/740 (7%)

Query  221  LAYASESPVNWCPGLGTVLANEEVTADGRSERGNFPVFKAKLRQWMMRITAYADRLLEDL  280
            LAY +E PVNW   LGT +ANEEV +DG SERG +PV +  +RQWM++ITAYA+RLLEDL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  281  DVLDWPEAIKLQQRNWIGRSEGARIDFPVHLQGDGDATITVFSTRQDTLFGATYMVLAPE  340
            + +DWPE+IK  QRNWIG+S GA + F V    D D  +TVF+TR DTLFGATY VLAPE
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVK---DTDKDFTVFTTRPDTLFGATYAVLAPE  264

Query  341  HELVDGIVPAVWPEGTHEVWTGGHATPaeavaayrkqaaaKSDVERQADAKEKTGVFTGA  400
            H LVD+I  +  +E+  +               Y++QA+ KSD+ R   AKEKTGV TG+
Sbjct  265  HALVDAITTSDQAEAVAD---------------YKRQASLKSDLARTDLAKEKTGVWTGS  309

Query  401  YAVNPVNGEKVPVFIADYVLMGYGTGAIMAVPAHDSRDFAFARAFELPMRCVVEPSDGRG  460
            YA+NPVNG  +PV IADYVL +YGTGAIMAVPAHD RD  FA+ F+L +  V+E ++   
Sbjct  310  YAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVE-  368

Query  461  QDPARWDDSFDSYDARIVNSSGAEISLDGLTVPEAKARMTQWLTERGIGEGTVNYRLRDW  520
                  + +F   + +I +       LDGL  + A A+M +WL   G+G+  V YRLRDW
Sbjct  369  ------EAAFTEDGLHINSD-----FLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDW  417

Query  521  LFSRQRYWGEPFPIVYDEQGVAHALPDSMLPVELPEVDDYRPRTFDPDDADTSPETPLSR  580
            LFSRQRYWGEP+PI+  E+G + A+P+S LP+ LP   D RP          + E+PL+ 
Sbjct  418  LFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLAN  469

Query  581  NEDWvdvvldlgdgPKRYRRETNTMPNWAGSCWYELRYLDPDNPDRLVDPQVESYWMGPR  640
              DW++V  + G      RRETNTMP+WAGS WY LRY+DP+N ++L D ++   W+   
Sbjct  470  VTDWLEVTREDGVKG---RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWL---  523

Query  641  EGQPSGGVDLYVGGSEHAVLHLLYARFWHKVLHDLGHVSSYEPYQRLFNQGMITAYVYRD  700
                   VD+YVGG+EHAVLHLLYARFWHKVL DLG V++ EP+Q+LFNQGMI +  YRD
Sbjct  524  ------PVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRD  577

Query  701  SRGFPVPAAEVEEREDGFYH--QGEKVRREHGKMGKSLKNAVTPDEICAEYGADTLRLYE  758
            SRG  V++  VE R+++F+H   GE + +  +KM+KSLKN V PD++  +YGADTLR+YE
Sbjct  578  SRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYE  637

Query  759  MAMGPLDVSRPWDTRAVVGSYRFLQRLWRNVVDEATGEATVVDQEPDEETLRALHKAIDG  818
            M MGPLD S +W   ++ GS +FL+R+ R +      E      +      +  + ++ +
Sbjct  638  MFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALD------KVYNETVKA  691

Query  819  IRTDMAALRFNTAIAKATELNNHLTKLPRVPRTVAETMVLLVAPLAPHIAEELWRRL-GH  877
            +  ++  ++FNTAIA+   + N   K  ++    A   V L+AP+APH++EELW+ L + 
Sbjct  692  VTEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTAS  751

Query  878  ESSLayadypvadpayvvdETVTCVVQIKGKVRARLEVPPAITeaeleklaladatvvaa  937
              S++Y   P  D + +V++ V  VVQIKGKV+A+L V+  ++  EL+ +ALA+  V A 
Sbjct  752  GESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAE  811

Query  938  lggaEIRKVIVRAPKLVNIV  957
            ++G +I KVI  + KLVNIV
Sbjct  812  IAGKDIIKVIAVPNKLVNIV  831


 Score =  134 bits (491),  Expect = 3e-32, Method: Compositional matrix adjust.
 Identities = 73/151 (49%), Positives = 102/151 (68%), Gaps = 11/151 (7%)

Query  22   AQIEARWQDLWEREGTFQAPNPGGGDLGGPAEVVERPKKFFMDMFPYPSGAGLHVGHPLG  81
            + IE++WQ +W  + TF++   ++           +PK + +DMFPYPSGAGLHVGHP G
Sbjct  7    TAIEPKWQAFWADNHTFKTGTDAS-----------KPKFYALDMFPYPSGAGLHVGHPEG  55

Query  82   YIATDVYARYHRMTGHNVLHTLGFDAFGLPAEQYAVQTGTHPRITTEANITTMRRQLRRL  141
            Y ATD+ +R+ R  GHNVLH +G DAFGLPAEQYA++TG +P   T  NI+  +RQ+  L
Sbjct  56   YTATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINAL  115

Query  142  GLGHDQRRSFATIDPAYYRWTQWIFLQIFNS  172
            G++ D  R   T DP YY+WTQWIF ++++ 
Sbjct  116  GFSYDWDREVNTTDPNYYKWTQWIFTKLYEK  146

1676) Strvi_7871 in NC_015957


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  486 bits (1832),  Expect = 3e-138, Method: Compositional matrix adjust.
 Identities = 353/741 (48%), Positives = 494/741 (67%), Gaps = 61/741 (8%)

Query  220  LAYASDAPVNWCPGLGTVLANEEVTADGRSERGNFPVFKAKLRQWNMRITAYAdrllddl  279
            LAY ++ PVNW   LGT +ANEEV +DG SERG +PV +  +RQW ++ITAYA+RLL+DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  280  deldWPEAIKLQQRNWIGLSEGARVDFPVTGHADAKITIFTTRQDTLFGATYMVLAPEHG  339
            +E+DWPE+IK  QRNWIG S GA V F V  ++D  +T+FTTR DTLFGATY VLAPEH+
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVK-DTDKDFTVFTTRPDTLFGATYAVLAPEHA  266

Query  340  LVDEIVPDAWPEGTRDAWTGGHATPAQAVDAYRKQAAAKSDVERQAEVKEKTGVFTGAYA  399
            LVD I                 +  A+AV  Y++QA+ KSD+ R    KEKTGV TG+YA
Sbjct  267  LVDAITT---------------SDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYA  311

Query  400  INPVSGEQVPVFIADYVLMGYGTGAIMAVPAHDSRDFAFARAFELPMRCVVEPSDDRGTD  459
            INPV+G ++PV IADYVL +YGTGAIMAVPAHD RD  FA+ F+L +  V+E ++     
Sbjct  312  INPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEE--  369

Query  460  PSTWDDAFASYDAKIVNSTGESVSLDGLGVVEAKARITEWLESRAIGEGTVNYRLRDWLF  519
                    A++    ++  ++   LDGL+   A A++ EWLE+ ++G+  V YRLRDWLF
Sbjct  370  --------AAFTEDGLHINSDF--LDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLF  419

Query  520  SRQRYWGEPFPIVYDEEGVAHALPESMLPLKLPEVEDYsprtfdpddsdtspetplsRNE  579
            SRQRYWGEP+PI+  E+G + A+PES LPL LP   D          +  + E+PL+   
Sbjct  420  SRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKD--------IRPSGTGESPLANVT  471

Query  580  DWVNVVLDLGDGRGPRPFRRETNTMPNWAGSCWYELRYLDPHNSERLVDPETERYWMGPR  639
            DW++V  + ++ +G    RRETNTMP+WAGS WY LRY+DPHN+E+L D E  + W+   
Sbjct  472  DWLEVTRE-DGVKG----RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLP--  524

Query  640  EGQPHGGVDLYVGGAEHAVLHLLYARFWSKVLFDLGHVSSVEPFHKLYNQGMIQAYVYRD  699
                   VD+YVGGAEHAVLHLLYARFW KVL+DLG V++ EPF+KL+NQGMI +  YRD
Sbjct  525  -------VDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRD  577

Query  700  SRGIAVPAAEVEERDGAYWY--EGEQVTRLLGKMGKSLKNAVTPDEICAEYGADTLRLYE  757
            SRG  V++  VE RDG++     GE++ +  +KM+KSLKN V PD++  +YGADTLR+YE
Sbjct  578  SRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYE  637

Query  758  MAMGPLDVSRPWDTRAVVGQYRLLQRLWRNvvdegtgevtvvdAEPDEATL-RALHKAID  816
            M MGPLD S +W   ++ G  ++L+R+ R          T   +E + ++L +  + ++ 
Sbjct  638  MFMGPLDASIAWSEEGLEGSRKFLDRVYR-------LITTKEITEENSGALDKVYNETVK  690

Query  817  GVRQDMEGLRFNTAIAKITELNNHVTKVREVPRSVAEGLVLLISPLAPHVAEELWRRL-G  875
            +V ++++ ++FNTAIA++  + N   K   +    A G+V LI+P+APH++EELW+ L +
Sbjct  691  AVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTA  750

Query  876  HSTSVVHEPFPVADPAYvvdetvtcvvqvKGKVKARLEVAPSVSDDDLEALALGDPAVVA  935
             + S+   P P  D + +V++ V  VVQ+KGKVKA+L VA  +S ++L+ +AL++  V A
Sbjct  751  SGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQA  810

Query  936  ALNGAGIRKVIVRAPKLVNIV  956
             + G +I KVI  + KLVNIV
Sbjct  811  EIAGKDIIKVIAVPNKLVNIV  831


 Score =  140 bits (516),  Expect = 4e-34, Method: Compositional matrix adjust.
 Identities = 74/150 (50%), Positives = 103/150 (69%), Gaps = 10/150 (6%)

Query  22   ADIEARWQDFWDAHGTYEAPNPSGDLAGDAEAVARPKKFVMDMFPYPSGAGLHVGHPLGY  81
            + IE++WQ FW  + T+ +          +   ++PK + +DMFPYPSGAGLHVGHP GY
Sbjct  7    TAIEPKWQAFWADNHTFKT----------GTDASKPKFYALDMFPYPSGAGLHVGHPEGY  56

Query  82   IATDVFARYHRMTGHNVLHTLGFDAFGLPAEQYAVQTGTHPRVSTEANIENMRRQLRRLG  141
             ATD+++R+ R  GHNVLH +G DAFGLPAEQYA++TG +P   T  NI N +RQ+  LG
Sbjct  57   TATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALG  116

Query  142  LGHDQRRSFATIDPDYYRWTQWIFLQIFNS  171
            ++ D  R   T DP+YY+WTQWIF ++++ 
Sbjct  117  FSYDWDREVNTTDPNYYKWTQWIFTKLYEK  146

1677) Tpau_4214 in NC_014158


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  486 bits (1832),  Expect = 3e-138, Method: Compositional matrix adjust.
 Identities = 353/739 (48%), Positives = 482/739 (66%), Gaps = 57/739 (7%)

Query  218  DHRLVYESNSLVNWCPGLGTVLANEEVTAEGRSERGNFPVYRKQLRQWMMRITAYSDRLI  277
            +  L YE++  VNW   LGT +ANEEV ++G SERG +PV RK +RQWM++ITAY++RL+
Sbjct  145  EKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLL  204

Query  278  DDLDVLDWPEKVKSMQRNWIGRSRGARVRFSPAAGAEPIEVFTTRQDTLFGATYLVLSPE  337
            +DL+ +DWPE +K MQRNWIG+S GA V F        + VFTTR DTLFGATY VL+PE
Sbjct  205  EDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPE  264

Query  338  HPLVDSLVADGWPAGTDDRWTGGaatpaeavaayraSIAAKSDLERQE-NKEKTGVFLGT  396
            H+LVD++ + + + +  D               Y+   + KSDL R +  KEKTGV  G+
Sbjct  265  HALVDAITTSDQAEAVAD---------------YKRQASLKSDLARTDLAKEKTGVWTGS  309

Query  397  TATNPVNGAQVPVFIGDYVLMGYGTGAIMAVPAHDIRDHEFATTFGLPIIEVVGSEAGVQ  456
             A NPVNG ++PV I+DYVL +YGTGAIMAVPAHD RD EFA  F L II V+ + + V+
Sbjct  310  YAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEG-GNVE  368

Query  457  DEAYTGDGPAVNSASAELDINGLTVADAKAAVTAYLERTGTGAGTVQYKLRDWLFARQRY  516
            + A+T DG  +NS      ++GL  A A A +   LE  G G   V Y+LRDWLF+RQRY
Sbjct  369  EAAFTEDGLHINSDF----LDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRY  424

Query  517  WGEPFPIVFDADGAPHALPESELAVLLPEVKDYAPVAFdpedsdsqpsppLAKATDWLHV  576
            WGEP+PI+   DG++ A+PESEL+++LP  KD  P +           +PLA+ TDWL+V
Sbjct  425  WGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSG--------TGESPLANVTDWLEV  476

Query  577  ELDLGDGLQDYTRDANVMPQWAGSSWYQLRYIDPTNSEAFCAKENEAYWMGPRPEVNGAN  636
              +  DG+++  R++N MPQWAGSSWY LRYIDP N+E +   E    W+          
Sbjct  477  TRE--DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWL----------  523

Query  637  DPGGVDLYVGGVEHAVLHLLYARFWHKVLFDLGYVSSKEPYRKLFNQGMIQAFAYTDSRG  696
                VD+YVGG EHAVLHLLYARFWHKVL+DLG V++KEP++KLFNQGMI + +Y DSRG
Sbjct  524  ---PVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRG  580

Query  697  VYVPAEDVVERDGKYFLGE--QEVNREYGKMGKSLKNSVAPDDIARDYGADTLRVYEMSM  754
              V+++ V  RDG +F  E  +E+++  +KM+KSLKN V PDD+  +YGADTLRVYEM M
Sbjct  581  ALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFM  640

Query  755  GPLDQDRAWATKDVVGSQRFLQRAWRTVVDEETGAVRVTGETPSDETMRVLHKTIAGVRE  814
            GPLD   AW+  ++ GS++FL+R  R +   E        E  S+   +V + T+ +V E
Sbjct  641  GPLDASIAWSEEGLEGSRKFLDRVYRLITTKE------ITEENSGALDKVYNETVKAVTE  694

Query  815  DYAEMRDNTAIAKLIELTNHLTKAYPGGAPRAAAEALTLMLAPVAPHIAEELWNRL-GHT  873
            +  +M+ NTAIA+L+ + N   K   +      A ++  ++AP APH++EELW+ L +  
Sbjct  695  QVDQMKFNTAIAQLMVFVNAANKE--DKLFSDYAKGFVQLIAPFAPHLGEELWQALTASG  752

Query  874  ESLAHGPFPQYDAQWLVEDTIEIPVQVKGKVRARITVGadasdealeaaalaepkvaell  933
            ES++  P P YD   LVE+ +EI VQ+KGKV+A++ V+ D S E L+  ALA+ KV   +
Sbjct  753  ESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEI  812

Query  934  eG-APRKVIVVSGKLVNVV  951
             G    KVI V+ KLVN+V
Sbjct  813  AGKDIIKVIAVPNKLVNIV  831


 Score =  132 bits (484),  Expect = 1e-31, Method: Compositional matrix adjust.
 Identities = 76/149 (52%), Positives = 106/149 (72%), Gaps = 10/149 (6%)

Query  23   GAIEQRWRDTWRDGGVFNAPNPVGPLQAADGALPADKLFLLDMFPYPSGAGLHVGHPLGF  82
             AIE +W+  W D   F++        ++D++ P  K++ LDMFPYPSGAGLHVGHP G+
Sbjct  7    TAIEPKWQAFWADNHTFKT--------GTDASKP--KFYALDMFPYPSGAGLHVGHPEGY  56

Query  83   IATDVFGRYHRMNGANVLHTMGFDAFGLPAEQYAVQTGTHPRVTTEKNVARYLEQIATLG  142
             ATD+++R+ R +G NVLH MG DAFGLPAEQYA++TG +P   T  N+A +  QI +LG
Sbjct  57   TATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALG  116

Query  143  LAHDERRRVSTTDPEFYHWTQWIFLQIYN  171
            ++ D  R V+TTDP++Y WTQWIF ++Y+
Sbjct  117  FSYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1678) NMBB_2163 in NC_017505


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  486 bits (1833),  Expect = 3e-138, Method: Compositional matrix adjust.
 Identities = 360/886 (41%), Positives = 533/886 (61%), Gaps = 71/886 (8%)

Query  7    YQPAAIEPAAQKKWDDARIFNVSEDASKPKYYCLSMFPYPSGK-LHMGHVRNYTIGDVLS  65
            Y+ +AIEP  Q  W D + F+ + DASKPK+Y L MFPYPSG  LH+GH   YT  D+LS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  66   RFKLLNGFNVMQPMGWDAFGMPAENAAMKNNVAPAAWTYDNIEYMKTQLKSLGFAIDWAR  125
            RFK  +G NV++PMGWDAFG+PAE+ AM     PA  T +NI   K Q+++LGF+ DW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  126  ETATCKPEYYRWEQWLFTKLFEKGIVYRKNGTVNWDPVDQTVLANEQVI-DGRGWRSGAL  184
            E  T  P+YY+W QW+FTKL+EKG+ Y  +  VNW     T +ANE+V+ DG + R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  185  IEKREIPMYYFKITDYAEELLNDLDKLEHWPEQVKTMQRNWIGKSRGMTVRFAVSDDSKQ  244
            + ++ +    +KIT YAE LL+DL+ ++ WPE +K MQRNWIGKS G  V F V D  K+
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  245  GLEGDYAKFLQVYTTRPDTLMGATYVavaaehplaaaaaaDKPELQAFIAECKAGSVAEA  304
                     + V+TTRPDTL GATY         A   A   ++    +A+ K  +   +
Sbjct  243  ---------FTVFTTRPDTLFGATYA--VLAPEHALVDAITTSDQAEAVADYKRQASLKS  291

Query  305  DMA----TMEKKGVPTGRYVVNPLNGDKLEVWIANYVLWGYGDGAVMAVPAHDERDFEFA  360
            D+A    + EK GV TG Y +NP+NG  + VWIA+YVL +YG GA+MAVPAHDERD EFA
Sbjct  292  DLARTDLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFA  351

Query  361  AKYSLPKKQVI---AVGDNAFDENQWQEWYGDKENGVLVNSGDLDGLDFQTAFDAVAAKL  417
             +++L    V+    V + AF            E+G+ +NS+ LDGLD  +A+  +   L
Sbjct  352  KQFNLDIIPVLEGGNVEEAAF-----------TEDGLHINSDFLDGLDKASAIAKMVEWL  400

Query  418  QSQGAGEPKTQYRLRDWGISRQRYWGCPIPIVHCEQCGDVPVPADQLPVVLP--ENVVPD  475
            +++G G+ +  YRLRDW +SRQRYWG PIPI+H E+    +VP  +LP+VLP   ++ P 
Sbjct  401  EAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPS  460

Query  476  GMG-SPLAKMPEFYETACPCCGGAAKRETDTMDTFMESSWYFFRYMSPKFSDGMVDPAAA  534
            G G SPLA++ +  E +    G  ++RET+TM     SSWY++RY+ P  ++ + D    
Sbjct  461  GTGESPLANVTDWLEVTRE-DGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELL  519

Query  535  KYWGAVDQYIGGIEHAILHLLYARFFTKLMRDEGLVNVDEPFERLLTQGMVVCETYYREN  594
            K W +VD Y+GG EHA+LHLLYARF  K++ D G+V   EPF++L+ QGM++  +Y   +
Sbjct  520  KQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY--RD  577

Query  595  DKGGKDWINPADVELTFDDKGRPISAVLKADGLPVVISGTEKMSKSKNNGVDPQELINAY  654
             +G+   +    VE       +  ++ +  +    +  +  KMSKS +N V+P+++++ Y
Sbjct  578  SRGAL--VATDKVE-------KRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQY  628

Query  655  GADTARLFMMFAAPPEQSLEWSDSGVEGAHRFLRRLWRTVYEYLKQGEAVKAFAGSQDGL  714
            GADT R++ MF +P + S+ WS+ G+EG+++FL R    VY  +   E     +G+ D  
Sbjct  629  GADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR----VYRLITTKEITEENSGALD--  682

Query  715  SKELKDLRHKLHATTAKVSDDYGRRQQFNTAIAAVMELLNQYDKTDTGGEQGRAVAQEVL  774
                     K+   T K   +   + +FNTAIA +M ++N  +K D        +  +  
Sbjct  683  ---------KVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK-------LFSDYA  726

Query  775  ETAVRLLWPIVPHICETLWSEL--NGAKLWEAGWPTVDEAALVKSEIEVMVQVNGKLRGK  832
               V+L+ P+ PH+ E LW  L  +G  +    WP+ DE+ LV +++E++VQ++GK+++K
Sbjct  727  KGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAK  786

Query  833  ITvaadaskadleaaalategavkFMEGKPAKKIIVVPGRLVNIVV  878
            + VA D S+ +L+  ALA E     + GK   K+I VP +LVNIV+
Sbjct  787  LVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

1679) leuS in NC_008767


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  486 bits (1832),  Expect = 3e-138, Method: Compositional matrix adjust.
 Identities = 361/886 (41%), Positives = 533/886 (61%), Gaps = 71/886 (8%)

Query  5    YQPAAIEPAAQKKWDDARIFNVSEDASKPKYYCLSMFPYPSGK-LHMGHVRNYTIGDVLS  63
            Y+ +AIEP  Q  W D + F+ + DASKPK+Y L MFPYPSG  LH+GH   YT  D+LS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RFKLLNGFNVMQPMGWDAFGMPAENAAMKNNVAPAAWTYDNIEYMKTQLKSLGFAIDWAR  123
            RFK  +G NV++PMGWDAFG+PAE+ AM     PA  T +NI   K Q+++LGF+ DW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ETATCKPEYYRWEQWLFTKLFEKGIVYRKNGTVNWDPVDQTVLANEQVI-DGRGWRSGAL  182
            E  T  P+YY+W QW+FTKL+EKG+ Y  +  VNW     T +ANE+V+ DG + R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  IEKREIPMYYFKITDYAEELLNDLDKLEHWPEQVKTMQRNWIGKSRGMTVRFAVSDDSKQ  242
            + ++ +    +KIT YAE LL+DL+ ++ WPE +K MQRNWIGKS G  V F V D  K+
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  GLEGDYAKLLQVYTTRPDTLMGATYVavaaehplaaaaaaDKPELQAFIAECKAGSVAEA  302
                     + V+TTRPDTL GATY         A   A   ++    +A+ K  +   +
Sbjct  243  ---------FTVFTTRPDTLFGATYA--VLAPEHALVDAITTSDQAEAVADYKRQASLKS  291

Query  303  DMA----TMEKKGVPTGRYVVNPLNGDKLEVWIANYVLWGYGDGAVMAVPAHDERDFEFA  358
            D+A    + EK GV TG Y +NP+NG  + VWIA+YVL +YG GA+MAVPAHDERD EFA
Sbjct  292  DLARTDLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFA  351

Query  359  AKYNLPKKQVI---AVGDNAFDANRWQEWYADKENGVLVNSGDLDGLDFQTAFDAVAAKL  415
             ++NL    V+    V + AF            E+G+ +NS+ LDGLD  +A+  +   L
Sbjct  352  KQFNLDIIPVLEGGNVEEAAF-----------TEDGLHINSDFLDGLDKASAIAKMVEWL  400

Query  416  QSQGAGEPKTQYRLRDWGISRQRYWGCPIPIVHCEQCGDVPVPADQLPVVLP--ENVVPD  473
            +++G G+ +  YRLRDW +SRQRYWG PIPI+H E+    +VP  +LP+VLP   ++ P 
Sbjct  401  EAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPS  460

Query  474  GMG-SPLAKMPEFYETACPCCGGAAKRETDTMDTFMESSWYFFRYMSPKFSDGMVDPAAA  532
            G G SPLA++ +  E +    G  ++RET+TM     SSWY++RY+ P  ++ + D    
Sbjct  461  GTGESPLANVTDWLEVTRE-DGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELL  519

Query  533  KYWGAVDQYIGGIEHAILHLLYARFFTKLMRDEGLVNVDEPFERLLTQGMVVCETYYREN  592
            K W +VD Y+GG EHA+LHLLYARF  K++ D G+V   EPF++L+ QGM++  +Y   +
Sbjct  520  KQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY--RD  577

Query  593  DKGGKDWINPADVELTFDDKGRPISAVLKADGLPVVISGTEKMSKSKNNGVDPQELINAY  652
             +G+   +    VE       +  ++ +  +    +  +  KMSKS +N V+P+++++ Y
Sbjct  578  SRGAL--VATDKVE-------KRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQY  628

Query  653  GADTARLFMMFAAPPEQSLEWSDSGVEGAHRFLRRLWRTVYEYLKQGEAVKAFAGSQDGL  712
            GADT R++ MF +P + S+ WS+ G+EG+++FL R    VY  +   E     +G+ D  
Sbjct  629  GADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR----VYRLITTKEITEENSGALD--  682

Query  713  SKELKDLRHKLHATTAKVSDDYGRRQQFNTAIAAVMELLNQYDKTDTGGEQGRAVAQEVL  772
                     K+   T K   +   + +FNTAIA +M ++N  +K D        +  +  
Sbjct  683  ---------KVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK-------LFSDYA  726

Query  773  ETAVRLLWPIVPHICETLWSEL--NGAKLWEAGWPTVDEAALVKSEIEVMVQVNGKLRGK  830
               V+L+ P+ PH+ E LW  L  +G  +    WP+ DE+ LV +++E++VQ++GK+++K
Sbjct  727  KGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAK  786

Query  831  ITvaadaskadleaaalategavkFMEGKPAKKIIVVPGRLVNIVV  876
            + VA D S+ +L+  ALA E     + GK   K+I VP +LVNIV+
Sbjct  787  LVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

1680) leuS in NC_017516


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  485 bits (1830),  Expect = 4e-138, Method: Compositional matrix adjust.
 Identities = 361/886 (41%), Positives = 532/886 (61%), Gaps = 71/886 (8%)

Query  5    YRPAAIEPAAQKKWDDARIFNVSEDASKPKYYCLSMFPYPSGK-LHMGHVRNYTIGDVLS  63
            Y  +AIEP  Q  W D + F+ + DASKPK+Y L MFPYPSG  LH+GH   YT  D+LS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RFKLLNGFNVMQPMGWDAFGMPAENAAMKNNVAPAAWTYDNIEYMKTQLKSLGFAIDWAR  123
            RFK  +G NV++PMGWDAFG+PAE+ AM     PA  T +NI   K Q+++LGF+ DW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ETATCKPEYYRWEQWLFTKLFEKGIVYRKNGTVNWDPVDQTVLANEQVI-DGRGWRSGAL  182
            E  T  P+YY+W QW+FTKL+EKG+ Y  +  VNW     T +ANE+V+ DG + R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  IEKREIPMYYFKITDYAEELLNDLDKLEHWPEQVKTMQRNWIGKSRGMTVRFAVSDDSKQ  242
            + ++ +    +KIT YAE LL+DL+ ++ WPE +K MQRNWIGKS G  V F V D  K+
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  GLEGDYAKFLQVYTTRPDTLMGATYVavaaehplaaaaaaDKPELQAFIAECKAGSVAEA  302
                     + V+TTRPDTL GATY         A   A   ++    +A+ K  +   +
Sbjct  243  ---------FTVFTTRPDTLFGATYA--VLAPEHALVDAITTSDQAEAVADYKRQASLKS  291

Query  303  DMA----TMEKKGVPTGRYVVNPLNGDKLEVWIANYVLWGYGDGAVMAVPAHDERDFEFA  358
            D+A    + EK GV TG Y +NP+NG  + VWIA+YVL +YG GA+MAVPAHDERD EFA
Sbjct  292  DLARTDLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFA  351

Query  359  TKYNLPKKQVI---AVGDNAFDENQWQEWYGDKENGVLVNSGDLDGLDFQTAFDAVAAKL  415
             ++NL    V+    V + AF            E+G+ +NS+ LDGLD  +A+  +   L
Sbjct  352  KQFNLDIIPVLEGGNVEEAAF-----------TEDGLHINSDFLDGLDKASAIAKMVEWL  400

Query  416  QSQGAGEPKTQYRLRDWGISRQRYWGCPIPIVHCEQCGDVPVPADQLPVVLP--ENVVPD  473
            +++G G+ +  YRLRDW +SRQRYWG PIPI+H E+    +VP  +LP+VLP   ++ P 
Sbjct  401  EAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPS  460

Query  474  GMG-SPLAKMPEFYETACPCCGGAAKRETDTMDTFMESSWYFFRYMSPKFSDGMVDPAAA  532
            G G SPLA++ +  E +    G  ++RET+TM     SSWY++RY+ P  ++ + D    
Sbjct  461  GTGESPLANVTDWLEVTRE-DGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELL  519

Query  533  KYWGAVDQYIGGIEHAILHLLYARFFTKLMRDEGLVNVDEPFERLLTQGMVVCETYYREN  592
            K W +VD Y+GG EHA+LHLLYARF  K++ D G+V   EPF++L+ QGM++  +Y   +
Sbjct  520  KQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY--RD  577

Query  593  DKGGKDWINPADVELTFDDKGRPISAVLKADGLPVVISGTEKMSKSKNNGVDPQELINAY  652
             +G+   +    VE       +  ++ +  +    +  +  KMSKS +N V+P+++++ Y
Sbjct  578  SRGAL--VATDKVE-------KRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQY  628

Query  653  GADTARLFMMFAAPPEQSLEWSDSGVEGAHRFLRRLWRTVYEYLKQGEAVKAFAGSQDGL  712
            GADT R++ MF +P + S+ WS+ G+EG+++FL R    VY  +   E     +G+ D  
Sbjct  629  GADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR----VYRLITTKEITEENSGALD--  682

Query  713  SKELKDLRHKLHATTAKVSDDYGRRQQFNTAIAAVMELLNQYDKTDTGGEQGRAVAQEVL  772
                     K+   T K   +   + +FNTAIA +M ++N  +K D        +  +  
Sbjct  683  ---------KVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK-------LFSDYA  726

Query  773  ETAVRLLWPIVPHICETLWSEL--NGAKLWEAGWPTVDEAALVKSEIEVMVQVNGKLRGK  830
               V+L+ P+ PH+ E LW  L  +G  +    WP+ DE+ LV +++E++VQ++GK+++K
Sbjct  727  KGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAK  786

Query  831  ITvaadaskadleaaalategavkFMEGKPAKKIIVVPGRLVNIVV  876
            + VA D S+ +L+  ALA E     + GK   K+I VP +LVNIV+
Sbjct  787  LVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

1681) leuS in NC_003112


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  485 bits (1830),  Expect = 4e-138, Method: Compositional matrix adjust.
 Identities = 361/886 (41%), Positives = 532/886 (61%), Gaps = 71/886 (8%)

Query  5    YRPAAIEPAAQKKWDDARIFNVSEDASKPKYYCLSMFPYPSGK-LHMGHVRNYTIGDVLS  63
            Y  +AIEP  Q  W D + F+ + DASKPK+Y L MFPYPSG  LH+GH   YT  D+LS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RFKLLNGFNVMQPMGWDAFGMPAENAAMKNNVAPAAWTYDNIEYMKTQLKSLGFAIDWAR  123
            RFK  +G NV++PMGWDAFG+PAE+ AM     PA  T +NI   K Q+++LGF+ DW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ETATCKPEYYRWEQWLFTKLFEKGIVYRKNGTVNWDPVDQTVLANEQVI-DGRGWRSGAL  182
            E  T  P+YY+W QW+FTKL+EKG+ Y  +  VNW     T +ANE+V+ DG + R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  IEKREIPMYYFKITDYAEELLNDLDKLEHWPEQVKTMQRNWIGKSRGMTVRFAVSDDSKQ  242
            + ++ +    +KIT YAE LL+DL+ ++ WPE +K MQRNWIGKS G  V F V D  K+
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  GLEGDYAKFLQVYTTRPDTLMGATYVavaaehplaaaaaaDKPELQAFIAECKAGSVAEA  302
                     + V+TTRPDTL GATY         A   A   ++    +A+ K  +   +
Sbjct  243  ---------FTVFTTRPDTLFGATYA--VLAPEHALVDAITTSDQAEAVADYKRQASLKS  291

Query  303  DMA----TMEKKGVPTGRYVVNPLNGDKLEVWIANYVLWGYGDGAVMAVPAHDERDFEFA  358
            D+A    + EK GV TG Y +NP+NG  + VWIA+YVL +YG GA+MAVPAHDERD EFA
Sbjct  292  DLARTDLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFA  351

Query  359  TKYNLPKKQVI---AVGDNAFDENQWQEWYGDKENGVLVNSGDLDGLDFQTAFDAVAAKL  415
             ++NL    V+    V + AF            E+G+ +NS+ LDGLD  +A+  +   L
Sbjct  352  KQFNLDIIPVLEGGNVEEAAF-----------TEDGLHINSDFLDGLDKASAIAKMVEWL  400

Query  416  QSQGAGEPKTQYRLRDWGISRQRYWGCPIPIVHCEQCGDVPVPADQLPVVLP--ENVVPD  473
            +++G G+ +  YRLRDW +SRQRYWG PIPI+H E+    +VP  +LP+VLP   ++ P 
Sbjct  401  EAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPS  460

Query  474  GMG-SPLAKMPEFYETACPCCGGAAKRETDTMDTFMESSWYFFRYMSPKFSDGMVDPAAA  532
            G G SPLA++ +  E +    G  ++RET+TM     SSWY++RY+ P  ++ + D    
Sbjct  461  GTGESPLANVTDWLEVTRE-DGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELL  519

Query  533  KYWGAVDQYIGGIEHAILHLLYARFFTKLMRDEGLVNVDEPFERLLTQGMVVCETYYREN  592
            K W +VD Y+GG EHA+LHLLYARF  K++ D G+V   EPF++L+ QGM++  +Y   +
Sbjct  520  KQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY--RD  577

Query  593  DKGGKDWINPADVELTFDDKGRPISAVLKADGLPVVISGTEKMSKSKNNGVDPQELINAY  652
             +G+   +    VE       +  ++ +  +    +  +  KMSKS +N V+P+++++ Y
Sbjct  578  SRGAL--VATDKVE-------KRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQY  628

Query  653  GADTARLFMMFAAPPEQSLEWSDSGVEGAHRFLRRLWRTVYEYLKQGEAVKAFAGSQDGL  712
            GADT R++ MF +P + S+ WS+ G+EG+++FL R    VY  +   E     +G+ D  
Sbjct  629  GADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR----VYRLITTKEITEENSGALD--  682

Query  713  SKELKDLRHKLHATTAKVSDDYGRRQQFNTAIAAVMELLNQYDKTDTGGEQGRAVAQEVL  772
                     K+   T K   +   + +FNTAIA +M ++N  +K D        +  +  
Sbjct  683  ---------KVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK-------LFSDYA  726

Query  773  ETAVRLLWPIVPHICETLWSEL--NGAKLWEAGWPTVDEAALVKSEIEVMVQVNGKLRGK  830
               V+L+ P+ PH+ E LW  L  +G  +    WP+ DE+ LV +++E++VQ++GK+++K
Sbjct  727  KGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAK  786

Query  831  ITvaadaskadleaaalategavkFMEGKPAKKIIVVPGRLVNIVV  876
            + VA D S+ +L+  ALA E     + GK   K+I VP +LVNIV+
Sbjct  787  LVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

1682) leuS in NC_003155


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  485 bits (1829),  Expect = 5e-138, Method: Compositional matrix adjust.
 Identities = 358/741 (49%), Positives = 499/741 (68%), Gaps = 61/741 (8%)

Query  226  LAYASEAPVNWSPGLGTVLANEEVTADGRSERGNFPVFKAKLRQWNMRITAYadrllddl  285
            LAY +E PVNW   LGT +ANEEV +DG SERG +PV +  +RQW ++ITAYA+RLL+DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  286  daldWPEAIKLQQRNWIGRSEGARVDFPIDG--EAVTVFTTRPDTLFGATYMVLAPEHPL  343
            + +DWPE+IK  QRNWIG+S GA V F + +     TVFTTRPDTLFGATY VLAPEH+L
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  344  VEKFTPAAWPEGTHDVWTGGHATPaeavaayraqaaSKSDVERQAEAKDKTGVFTGAYAT  403
            V+ +T +  +E+  D               Y+ QA+ KSD+ R   AK+KTGV TG+YA 
Sbjct  268  VDAITTSDQAEAVAD---------------YKRQASLKSDLARTDLAKEKTGVWTGSYAI  312

Query  404  NPVSGEQVPVFIADYVLMGYGTGAIMAVPAHDTRDFAFARAFELSMRCVVEPSDDRGTDP  463
            NPV+G ++PV IADYVL +YGTGAIMAVPAHD RD  FA+ F+L +  V+E ++      
Sbjct  313  NPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEE---  369

Query  464  STWDDAFASYDAKIVNSSSGEISLDGLGVVEAKARITEWLERKGLGEGTVNFRLRDWLFS  523
                   A++    ++ +S+   LDGL+   A A++ EWLE  G+G+  V +RLRDWLFS
Sbjct  370  -------AAFTEDGLHINSD--FLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  524  RQRYWGEPFPIVYDEDGIAHAlpesmlplelpeveDYSPRTFDPDDANTSPETPLSRNED  583
            RQRYWGEP+PI+  EDG + A+PES LPL LP   D  P        + + E+PL+   D
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTD  472

Query  584  WVNVTLDLGDGRGPQKYRRETNTMPNWAGSCWYELRYLDPHNDQKLVDPAIEQYWMGPRE  643
            W++VT + ++ +G    RRETNTMP+WAGS WY LRY+DPHN +KL D  + + W+    
Sbjct  473  WLEVTRE-DGVKG----RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLP---  524

Query  644  GQPTGGVDLYVGGAEHAVLHLLYARFWSKVLFDLGHISSAEPFHKLFNQGMIQAYVYRDS  703
                  VD+YVGGAEHAVLHLLYARFW KVL+DLG +++ EPF+KLFNQGMI +  YRDS
Sbjct  525  ------VDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDS  578

Query  704  RGIAVPAAEVEERDGAYYY--QGEKVSRLLGKMGKSLKNAVTPDEICAEYGADTLRLYEM  761
            RG  V++  VE RDG+++    GE + +  +KM+KSLKN V PD++  +YGADTLR+YEM
Sbjct  579  RGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEM  638

Query  762  AMGPLDVSRPWDTRAVVGQFRLLQRLWRNVVDEATGEVTVVDAEPDEETLRALHKAIDGV  821
             MGPLD S +W   ++ G  ++L+R+ R +   +T E+T  ++ + +   +  + ++ +V
Sbjct  639  FMGPLDASIAWSEEGLEGSRKFLDRVYRLI---TTKEITEENSGALD---KVYNETVKAV  692

Query  822  RQDLEGMRFNTAIAKVTELNNQLTKAGGPVPRTVAESLVLLVAPLAPHIAEELWRKL-GH  880
             ++++ M+FNTAIA++  + N   K  + +    A ++V L+AP+APH++EELW+ L + 
Sbjct  693  TEQVDQMKFNTAIAQLMVFVNAANKE-DKLFSDYAKGFVQLIAPFAPHLGEELWQALTAS  751

Query  881  NDSVVHQDFPVADPAYVVDEAVTCVVQIKGKVKARLEVSPAISEEELEKVALADEKVVAA  940
             +S+     P  D + +V++ V  VVQIKGKVKA+L V+  +S EEL+ VALA+EKV A 
Sbjct  752  GESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAE  811

Query  941  LGGAGIRKVIVRAPKLVNIVT  961
            ++G +I KVI  + KLVNIV 
Sbjct  812  IAGKDIIKVIAVPNKLVNIVI  832


 Score =  140 bits (516),  Expect = 3e-34, Method: Compositional matrix adjust.
 Identities = 77/150 (52%), Positives = 103/150 (69%), Gaps = 10/150 (6%)

Query  24   AEIEARWQDFWDAEGTYEAPNPTGDLAGGPALVAKPKKFVMDMFPYPSGAGLHVGHPLGY  83
            + IE++WQ FW  + T+ +   +          +KPK + +DMFPYPSGAGLHVGHP GY
Sbjct  7    TAIEPKWQAFWADNHTFKTGTDA----------SKPKFYALDMFPYPSGAGLHVGHPEGY  56

Query  84   IATDVFARFQRMTGHNVLHTLGFDAFGLPAEQYAVQTGTHPRVSTEANIENMKVQLRRLG  143
             ATD+++RF+R  GHNVLH +G DAFGLPAEQYA++TG +P   T  NI N K Q+  LG
Sbjct  57   TATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALG  116

Query  144  LGHDKRRSFATIDPDYYKWTQWIFLQIFNS  173
            ++ D  R   T DP+YYKWTQWIF ++++ 
Sbjct  117  FSYDWDREVNTTDPNYYKWTQWIFTKLYEK  146

1683) Tmar_2197 in NC_014831


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  485 bits (1829),  Expect = 6e-138, Method: Compositional matrix adjust.
 Identities = 309/676 (46%), Positives = 435/676 (65%), Gaps = 48/676 (7%)

Query  7    YNFHAAEKKWRQRWAEEGLYHVEADPSRPKFYCLEMYPYPSGK-LHMGHVRNYSIGDATA  65
            Y+  A E KW+  WA++  +   +D+S+PKFY L+M+PYPSG  LH+GH   Y+  D  +
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  66   RFLRMRGYNVLYPMGWDSFGLPAENAAIANQTHPAEWTYANIAAMREQMQRLGLSYDWRR  125
            RF R +G NVL PMGWD+FGLPAE+ A+    +PAE T  NIA  + Q++ LG+SYDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  126  EIACSHPGYYKWTQWLFLLLYKRGLVERKKAPVNWCPRCATVLANEQV-EDGACWRCGTP  184
            E+  ++P YYKWTQW+F  LY +GL      PVNW    +T +ANE+V  DG+  R G P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  185  VEKRELEQWFFRITAYADRLLKDLDLLEGWPERVKVMQRNWIGRSEGMELDFPIAGRDEK  244
            V ++ + QW ++ITAYA+RLL DL+ ++ WPE +K MQRNWIG+S G ++ F + + D  
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  245  LTVFTTRHDTVYGATFMVLAPDHPLTLELARGTEQEAAVRAFVERVTRLTVRDRAEALDA  304
            +TVFTTR DT++GAT+ VLAP+H+L ++    ++Q  AV  +  + +  +   R++    
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHAL-VDAITTSDQAEAVADYKRQASLKSDLARTDLAKE  301

Query  305  KEGVFTGAYAINPVTGERIPIWTANYVLMDYGTGAIQAVPAHDQRDFEFARKYGLPVRVV  364
            K GV TG+YAINPV G  +P+W A+YVL  YGTGAI AVPAHD+RD EFA+++ L +  V
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPV  361

Query  365  IQGEGVPADGDRLEEAYTGPGRMIHSGPYDGMDSREAYRRMAEDFERRGIGRRTVNYRLR  424
            ++G  V       E A+T  G  I+S+  DG+D   A  +M E +E  G+G   V YRLR
Sbjct  362  LEGGNVE------EAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  425  DWLISRQRYWGAPIPIVYCDRCGIVPVPEDQLPVLLP--DDVR-FQVGASPLATSESFVR  481
            DWL+SRQRYWG PIPI+  +     +VPE +LP++LP   D+R    G SPLA     + 
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  482  TTCPSCGGPARRETDTMDTFVDSSWYYYRYTSPRDEHQPFDREKVFYWLPVDQYIGGIEH  541
             T    G  +RRET+TM    +SSWYY RY  P++ ++  D E +  WLPVD Y+GG EH
Sbjct  476  VTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEH  534

Query  542  AVLHLLYSRFITKVLYDEGLVPSPEPFRRLLTQGMVI-------------------KDG-  581
            AVLHLLY+RF  KVLYD G+VP+ EPF++L+ QGM++                   +DG 
Sbjct  535  AVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGS  594

Query  582  --------------AKMSKSKGNVVSPEDILEEYGADATRLFILFAAPPERDLEWSEHGI  627
                          AKMSKS  NVV+P+D++E+YGAD+ R++ +F +P +  + WSE+G+
Sbjct  595  FFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGL  654

Query  628  EGASRFVQRVWRLVTG  643
            EG+ +F++RV RL+T 
Sbjct  655  EGSRKFLDRVYRLITT  670


 Score = 81.5 bits (290),  Expect = 3e-16, Method: Compositional matrix adjust.
 Identities = 62/162 (39%), Positives = 102/162 (63%), Gaps = 12/162 (7%)

Query  736  VHRAIARVTTDIAERMQYNTAVAALMELVNAIYGYRDRVEPaaqradllaaaldrllrml  795
            V     +  T+  ++M++NTA+A LM +VNA          A +   L++     +++++
Sbjct  684  VYNETVKAVTEQVDQMKFNTAIAQLMVFVNA----------ANKEDKLFSDYAKGFVQLI  733

Query  796  aPFTPYLAEEAWELLGWRATRGSVHRQPWPAWDPAVLEAGTVEIVVQVNGKVRDRLQVPA  855
            APF+P L+EE W+ L   A+  S+   PWP+ D + L    VEIVVQ++GKV+ +L V+ 
Sbjct  734  APFAPHLGEELWQALT--ASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAK  791

Query  856  DLSEEELRQRALASPRVRDWLDGKTVARVITVPGRLVNVVVK  897
            DLS EEL++ ALA+ +V+  + GK + +VI+VP +LVN+V+K
Sbjct  792  DLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

1684) leuS in NC_017501


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  485 bits (1828),  Expect = 6e-138, Method: Compositional matrix adjust.
 Identities = 361/886 (41%), Positives = 531/886 (60%), Gaps = 71/886 (8%)

Query  5    YQPAAIEPAAQKKWDDARIFNVSEDASKPKYYCLSMFPYPSGK-LHMGHVRNYTIGDVLS  63
            Y+ +AIEP  Q  W D + F+ + DASKPK+Y L MFPYPSG  LH+GH   YT  D+LS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RFKLLNGFNVMQPMGWDAFGMPAENAAMKNNVAPAAWTYDNIEYMKTQLKSLGFAIDWAR  123
            RFK  +G NV++PMGWDAFG+PAE+ AM     PA  T +NI   K Q+++LGF+ DW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ETATCKPEYYRWEQWLFTKLFEKGIVYRKNGTVNWDPVDQTVLANEQVI-DGRGWRSGAL  182
            E  T  P+YY+W QW+FTKL+EKG+ Y  +  VNW     T +ANE+V+ DG + R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  IEKREIPMYYFKITDYAEELLNDLDKLEHWPEQVKTMQRNWIGKSRGMTVRFAVSDDSKQ  242
            + ++ +    +KIT YAE LL+DL+ ++ WPE +K MQRNWIGKS G  V F V D  K+
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  GLEGDYANFLQVYTTRPDTLMGATYVavaaehplataaaaDKPELQAFIAECKAGSVAEA  302
                     + V+TTRPDTL GATY         A   A   ++    +A+ K  +   +
Sbjct  243  ---------FTVFTTRPDTLFGATYA--VLAPEHALVDAITTSDQAEAVADYKRQASLKS  291

Query  303  DMA----TMEKKGVPTGRYVVNPLNGDKLEVWIANYVLWGYGDGAVMAVPAHDERDFEFA  358
            D+A    + EK GV TG Y +NP+NG  + VWIA+YVL +YG GA+MAVPAHDERD EFA
Sbjct  292  DLARTDLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFA  351

Query  359  AKYSLPKKQVI---AVGDNAFDANRWQEWYGDKENGVLVNSGDLDGLDFQTAFDAVAAKL  415
             +++L    V+    V + AF            E+G+ +NS+ LDGLD  +A+  +   L
Sbjct  352  KQFNLDIIPVLEGGNVEEAAF-----------TEDGLHINSDFLDGLDKASAIAKMVEWL  400

Query  416  QNQGAGEPKTQYRLRDWGISRQRYWGCPIPIVHCEKCGDVPVPADQLPVVLP--ENVVPD  473
            + +G G+ +  YRLRDW +SRQRYWG PIPI+H E     +VP  +LP+VLP   ++ P 
Sbjct  401  EAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPS  460

Query  474  GMG-SPLAKMPEFYETTCPCCGGAAKRETDTMDTFMESSWYFFRYMSPKFSDGMVSAEAA  532
            G G SPLA++ +  E T    G  ++RET+TM     SSWY++RY+ P  ++ +   E  
Sbjct  461  GTGESPLANVTDWLEVTRE-DGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELL  519

Query  533  KYWGAVDQYIGGIEHAILHLLYARFFTKLMRDEGLVNVGEPFERLLTQGMVVCETYYREN  592
            K W +VD Y+GG EHA+LHLLYARF  K++ D G+V   EPF++L+ QGM++  +Y   +
Sbjct  520  KQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY--RD  577

Query  593  DKGGKDWINPADVELTFDDKGRPVSAVLKADGLPVVISGTEKMSKSKNNGVDPQELINAY  652
             +G+   +    VE       +  ++ +  +    +  +  KMSKS +N V+P+++++ Y
Sbjct  578  SRGAL--VATDKVE-------KRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQY  628

Query  653  GADTARLFMMFAAPPEQSLEWSDSGVEGAHRFLRRLWRTVYEYLKQGEAVKAFAGSQDGL  712
            GADT R++ MF +P + S+ WS+ G+EG+++FL R    VY  +   E     +G+ D  
Sbjct  629  GADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDR----VYRLITTKEITEENSGALD--  682

Query  713  SKELKDLRHKLHATTAKVSDDYGRRQQFNTAIAAVMELLNQYDKTDTGGEQGRAVAQEVL  772
                     K+   T K   +   + +FNTAIA +M ++N  +K D        +  +  
Sbjct  683  ---------KVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK-------LFSDYA  726

Query  773  ETAVRLLWPIVPHICETLWSEL--NGAKLWEAGWPTVDEAALVKSEIEVMVQVNGKLRGK  830
               V+L+ P+ PH+ E LW  L  +G  +    WP+ DE+ LV +++E++VQ++GK+++K
Sbjct  727  KGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAK  786

Query  831  ITvaadaskadleaaalategavkFMEGKPAKKIIVVPGRLVNIVV  876
            + VA D S+ +L+  ALA E     + GK   K+I VP +LVNIV+
Sbjct  787  LVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

1685) Belba_0205 in NC_018010


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  484 bits (1826),  Expect = 1e-137, Method: Compositional matrix adjust.
 Identities = 326/727 (45%), Positives = 473/727 (66%), Gaps = 50/727 (6%)

Query  206  LTFLAETTVNWCAALGTVLSNDEV-KDGFSERGGHPVERKKMMQWSMRITAYADRLLKGL  264
            L++ AE  VNW   LGT ++N+EV  DG SERGG PV RK M QW ++ITAYA+RLL +L
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  265  DTVEWTEPIKEMQRNWIGKSKGAEMVFQVKGHDKQIKVFTTRIDTIYGVTYLALAPEHDY  324
            + V+W E+IK+MQRNWIGKS GA++ F+VK+ DK++ VFTTR DT++G TY  LAPEH  
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  325  VEDLITEDQRTTAEAYVEVAKNRSERDRMTDVKTISGAFTGSYAINPFNGEEIQIWIADY  384
            V+ + T DQ  +   Y   A  +S+  R    K  +G  TGSYAINP NG E+ +WIADY
Sbjct  268  VDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAINPVNGKEMPVWIADY  327

Query  385  VLAGYGTGAVMAVPAHDERDYNFAKHFGLEIRQVIEGS-MEEGSFPGKGGTIINSDFLSG  443
            VLA+YGTGA+MAVPAHDERD +FAK+F L+I  V+EG+ +EE++F   +G  INSDFL G
Sbjct  328  VLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEAAFTE-DGLHINSDFLDG  386

Query  444  LEMQAAMDKAIEFVEERKIGKGKIQFRMRDAIFTRQRYWGEPLP-VYFKDGLPYLIEEKD  502
            L+  +A+ K +E +E   +G+ ++ +R+RD +F+RQRYWGEP+P +   DG +  + E +
Sbjct  387  LDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESE  446

Query  503  LPLVLPEVDKYLPTEDGEPPLARAKNWNYKTAEGEFPLER--STMPGWAGSSWYFFRYMD  560
            LPLVLP      P+  GE+PLA   +W   T E+     R  +TMP WAGSSWY++RY+D
Sbjct  447  LPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYID  506

Query  561  PKNETQFVDQEIAKYWGAVDLYIGGAEHATGHLLYSRFWTKFLFDIGVVNIEEPFQKMIN  620
            P N  ++ D+E+ K W +VD+Y+GGAEHA  HLLY+RFW K L+D+GVV   EPFQK++N
Sbjct  507  PHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFN  566

Query  621  QGMIQGRSNFVYRIKGSNKFISLGLKDDYETSAMHVDVNIVHNDQLNLDKFKTWRPDLAD  680
            QGMI G S   YR  +   +++ +  +  + S  HV+      ++L+             
Sbjct  567  QGMILGTS---YR-DSRGALVATDKVEKRDGSFFHVET----GEELE-------------  605

Query  681  AEFILEDGKYICGAEVEKMSKSKYNVVNPDDIIERYGADTLRLYEMFLGPLEQFKPWNTN  740
                             KMSKS  NVVNPDD++E+YGADTLR+YEMF+GPL+   +W+ +
Sbjct  606  -------------QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEE  652

Query  741  GIDGVSKFLKKLWKLYHDSNGEVSISNEAPSQEELKTLHKTIKKTEEDLENYSFNTSVAS  800
            G++G  KFL ++ +L    +    I++E ++  + K  + T+K   E++++  FNT++A 
Sbjct  653  GLEGSRKFLDRVYRLITTKE----ITEENSGALD-KVYNETVKAVTEQVDQMKFNTAIAQ  707

Query  801  FMICVNELTALKCNK--KAILEPLAILVSPYAPHIAEELWAIL-GNEKSIIYASFPEFKE  857
            +M+ VN  +A K +K        +  L++P+APH++EELW  L ++  SI Y + P + E
Sbjct  708  LMVFVN--AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDE  765

Query  858  EFLIENSHEYPVSINGKMRTKlslslslTKEEIEKAALEDEIVQKWLEGNAPKKMIVVPG  917
              L+EN  E  V I+GK+++KL ++  L++EE++  AL +E VQ  + G+   K+I VP 
Sbjct  766  SKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPN  825

Query  918  KIVNIVI  924
            K+VNIVI
Sbjct  826  KLVNIVI  832


 Score =  181 bits (670),  Expect = 2e-46, Method: Compositional matrix adjust.
 Identities = 88/141 (63%), Positives = 116/141 (83%), Gaps = 0/141 (0%)

Query  4    YNSQEIEKKWQTYWEKNQIFNAKVDASKPKFYSLDMFPYPSGAGLHVGHPLGYIASDIIT  63
            Y+   IE KWQ++W  N+ F++  DASKPKFY+LDMFPYPSGAGLHVGHP GY A+DI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYKRLQGFNVLHPMGYDSFGLPAEQYAIQTGQHPAVTTEQNIKRYTEQLKNIGFAFDWDK  123
            R+KR QG NVLHPMG D+FGLPAEQYA++TG++PA  T +NI  +  Q++ +GF++DWD+
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVRTSDPAYYRWTQWIFMQLF  144
            EV T+DP YY+WTQWIF +L+
Sbjct  124  EVNTTDPNYYKWTQWIFTKLY  144

1686) leuS in NC_010400


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  484 bits (1824),  Expect = 1e-137, Method: Compositional matrix adjust.
 Identities = 352/877 (41%), Positives = 539/877 (62%), Gaps = 60/877 (6%)

Query  10   YQANTIEPSVQQDWENRKVFKVADTVEGKHRYILSMFPYPSGK-LHMGHVRNYTIGDVIS  68
            Y+  +IEP  Q  W +   FK +        Y L MFPYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  69   RFYRLKGETVLQPMGWDAFGLPAENAAIAHKVAPAKWTFENIAYMRDQLKKLGLSVDWDR  128
            RF R +G+ VL+PMGWDAFGLPAE+ A+     PA  T ENIA  + Q++ LG+S DWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  129  EFATCTPEYYHWEQWLFVQLYKKGLIYRKLSTVNW-DPVDQTVLANEQVENGRGWRSGAL  187
            E  T  P+YY W QW+F +LY KGL Y     VNW + ++ ++  +E + +G + R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  188  VEKRDIPMYYFRITDYAQEllddldtlqdGWPQQVLTMQRNWIGRSTGMEITFPSANTEI  247
            V ++ +    ++IT YA+      D  + +WP+ +  MQRNWIG+STG ++TF   +T+ 
Sbjct  184  VVRKPMRQWMLKITAYAE--RLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD-  240

Query  248  YADGLTVYTTRADTLMGVTYVAVAAEHPL--ALKAAENNPELAAFIEECRI-GSVAEADL  304
               ++TV+TTR+DTL G TY  +A+EH+L  A+ ++++   +A +  +  + + +A +DL
Sbjct  241  --KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDL  298

Query  305  ATAEKKGMATGLFVKHPVTGEELPVWIANYVLMSYGSGAVMAVPAHDERDFEFANKFNLP  364
            A  EK G+ TG +  +PV G E+PVWIA+YVL SYG+GA+MAVPAHDERD EFA++FNL 
Sbjct  299  AK-EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLD  357

Query  365  IKQVIDAKGADDADYSATEWQEWYGSKEGKLVNSGEFDGLEFQAAFDAFLAKLEPQGLAN  424
            I  V+++   ++A ++           +G  +NS+ +DGL+  +A+   +  LE++G++N
Sbjct  358  IIPVLEGGNVEEAAFTE----------DGLHINSDFLDGLDKASAIAKMVEWLEAEGVGN  407

Query  425  SKVQFRLRDWGVSRQRYWGCPIPMINCDTCGQVTVPEDQlpvvlptdvvpdGSG---NPL  481
             +V +RLRDW  SRQRYWG PIP+I+ +     +VPE +LP+VLP       SG   +PL
Sbjct  408  ENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPL  467

Query  482  NKMPEFYETKCPCCGGDARRETDTLDTFVESSWYYARYASPDFTGGIVKPEAAKNWLPVN  541
             ++ +  E      G  +RRET+T+     SSWYY RY  P+ T  +   E  K+WLPV+
Sbjct  468  ANVTDWLEVTRE-DGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVD  526

Query  542  QYIGGVEHAILHLLYARFFHKLMHDEGVVQGNEPFTNLLTQGMVLADTFYREAENGKKTW  601
             Y+GG EHA+LHLLYARF HK++ D GVV  +EPF +L+ QGM+L+ + YR++       
Sbjct  527  IYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS-YRDS-------  578

Query  602  FNPANIELERDEKGRIISAKYSGDGQEVIIGGQEKMSKSKNNGIDPQAIIDQYGADTARV  661
               A +  ++ EK    ++ +  +  E +  +  KMSKS +N ++P+ +++QYGADT RV
Sbjct  579  -RGALVATDKVEKRD--GSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRV  635

Query  662  FMMFAAPPDQSLEWSDAGVEGANRFLKRVWRLVASFLEKGNSATAIDKANLSKDAQDLRR  721
            + MF +P D S+ WS+ G+EG+ +FL RV RL+++            K     ++  L +
Sbjct  636  YEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITT------------KEITEENSGALDK  683

Query  722  KTHETIQKVSDDIERRHAFNTAIAALMELLNASNKFEAKDDNDVAVEREAIttlltllAP  781
              +ET++ V++++++   FNTAIA LM ++NA+NK       +  +  +    ++ L+AP
Sbjct  684  VYNETVKAVTEQVDQMK-FNTAIAQLMVFVNAANK-------EDKLFSDYAKGFVQLIAP  735

Query  782  FAPHLSQTL---LAQFGTDLTEATFPEVDASALTRNTQTIVVQVNGKLRGKLEVSVDISK  838
            FAPHL++ L   L+  G  ++    P  D S L  N   IVVQ++GK+++KL V+ D+S+
Sbjct  736  FAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSR  795

Query  839  DELLAQAKALPEVQQFLTGP-TKKEIVVPNKLVNLVV  874
            +EL   A A   VQ  ++G    K I VPNKLVN+V+
Sbjct  796  EELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

1687) leuS in NC_011035


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  484 bits (1823),  Expect = 1e-137, Method: Compositional matrix adjust.
 Identities = 361/886 (41%), Positives = 540/886 (61%), Gaps = 71/886 (8%)

Query  5    YQPAAIEPAAQKKWDDARISNVSEDASKPKYYCLSMFPYPSGK-LHMGHVRNYTIGDVLS  63
            Y+ +AIEP  Q  W D +  + + DASKPK+Y L MFPYPSG  LH+GH   YT  D+LS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RFKLLNGFNVMQPMGWDAFGMPAENAAMKNNVAPAAWTYDNIEYMKTQLKSLGFAVDWER  123
            RFK  +G NV++PMGWDAFG+PAE+ AM     PA  T +NI   K Q+++LGF+ DW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVATCKPEYYRWEQWLFTKLFEKGIVYRKNGTVNWDPVDQTVLANEQVI-DGRGWRSGAL  182
            EV T  P+YY+W QW+FTKL+EKG+ Y  +  VNW     T +ANE+V+ DG + R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  IEKREIPMYYFKITDYAEELLNDLDKLEHWPEQVKTMQRNWIGKSRGMTVRFAVSDDSKQ  242
            + ++ +    +KIT YAE LL+DL+ ++ WPE +K MQRNWIGKS G  V F V D  K+
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  GLEGDYAKFLQVYTTRPDTLMGATYVavaaehplataaaaDKPELQAFIAECKAGSVAEA  302
                     + V+TTRPDTL GATY         A   A   ++    +A+ K  +   +
Sbjct  243  ---------FTVFTTRPDTLFGATYA--VLAPEHALVDAITTSDQAEAVADYKRQASLKS  291

Query  303  DMA----TMEKKGVPTGRYVVNPLNGDKLEVWIANYVLWGYGDGAVMAVPAHDERDFEFA  358
            D+A    + EK GV TG Y +NP+NG  + VWIA+YVL +YG GA+MAVPAHDERD EFA
Sbjct  292  DLARTDLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFA  351

Query  359  AKYNLPKKQVI---AVGDNAFDANRWQEWYGDKENGVLVNSGDLDGLDFQTAFDAVAAKL  415
             ++NL    V+    V + AF            E+G+ +NS+ LDGLD  +A+  +   L
Sbjct  352  KQFNLDIIPVLEGGNVEEAAF-----------TEDGLHINSDFLDGLDKASAIAKMVEWL  400

Query  416  QSQGAGEPKTQYRLRDWGISRQRYWGCPIPIVHCEKCGDVPVPADQLPVVLP--ENVVPD  473
            +++G G+ +  YRLRDW +SRQRYWG PIPI+H E     +VP  +LP+VLP   ++ P 
Sbjct  401  EAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPS  460

Query  474  GMG-SPLAKMPEFYETSCPCCGGAAKRETDTMDTFMESSWYFFRYMSPKFSDGMVSAESA  532
            G G SPLA++ +  E +    G  ++RET+TM     SSWY++RY+ P  ++ +   E  
Sbjct  461  GTGESPLANVTDWLEVTRE-DGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELL  519

Query  533  KYWGAVDQYIGGIEHAILHLLYARFFTKLMRDEGLVNVDEPFERLLTQGMVVCETYYREN  592
            K W +VD Y+GG EHA+LHLLYARF  K++ D G+V   EPF++L+ QGM++  +Y   +
Sbjct  520  KQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY--RD  577

Query  593  DKGGKDWINPADVELTFDDKGRPVSAVLKADGLPVVISGTEKMSKSKNNGVDPQELINAY  652
             +G+   +    VE       +  ++ +  +    +  +  KMSKS +N V+P+++++ Y
Sbjct  578  SRGAL--VATDKVE-------KRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQY  628

Query  653  GADTARLFMMFAAPPEQSLEWSDSGVEGAHRFLRRLWRTVYEYLKQGGAVKAFAGNQDGL  712
            GADT R++ MF +P + S+ WS+ G+EG+++FL R+ R +        + K ++ ++ G 
Sbjct  629  GADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLI--------TTKEITEENSG-  679

Query  713  SKELKDLRHKLHSTTAKVSDDYGRRQQFNTAIAAVMELLNQYDKTDTGSEQGRAVAQEVL  772
               L    +K+ + T K   +   + +FNTAIA +M ++N  +K D        +  +  
Sbjct  680  --AL----DKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK-------LFSDYA  726

Query  773  EAAVRLLWPIVPHICETLWSEL--NGAKLWEAGWPTVDEAALVKSEIEVMVQVNGKLRGK  830
             + V+L+ P+ PH+ E LW  L  +G  +    WP+ DE+ LV +++E++VQ++GK+++K
Sbjct  727  KGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAK  786

Query  831  ITvaadaskadleaaalanegavkFMEGKPAKKIIVVPGRLVNIVV  876
            + VA D S+ +L+  ALANE     + GK   K+I VP +LVNIV+
Sbjct  787  LVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

1688) leuS in NC_017511


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  484 bits (1823),  Expect = 1e-137, Method: Compositional matrix adjust.
 Identities = 361/886 (41%), Positives = 540/886 (61%), Gaps = 71/886 (8%)

Query  5    YQPAAIEPAAQKKWDDARISNVSEDASKPKYYCLSMFPYPSGK-LHMGHVRNYTIGDVLS  63
            Y+ +AIEP  Q  W D +  + + DASKPK+Y L MFPYPSG  LH+GH   YT  D+LS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RFKLLNGFNVMQPMGWDAFGMPAENAAMKNNVAPAAWTYDNIEYMKTQLKSLGFAVDWER  123
            RFK  +G NV++PMGWDAFG+PAE+ AM     PA  T +NI   K Q+++LGF+ DW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVATCKPEYYRWEQWLFTKLFEKGIVYRKNGTVNWDPVDQTVLANEQVI-DGRGWRSGAL  182
            EV T  P+YY+W QW+FTKL+EKG+ Y  +  VNW     T +ANE+V+ DG + R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  IEKREIPMYYFKITDYAEELLNDLDKLEHWPEQVKTMQRNWIGKSRGMTVRFAVSDDSKQ  242
            + ++ +    +KIT YAE LL+DL+ ++ WPE +K MQRNWIGKS G  V F V D  K+
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  243  GLEGDYAKFLQVYTTRPDTLMGATYVavaaehplataaaaDKPELQAFIAECKAGSVAEA  302
                     + V+TTRPDTL GATY         A   A   ++    +A+ K  +   +
Sbjct  243  ---------FTVFTTRPDTLFGATYA--VLAPEHALVDAITTSDQAEAVADYKRQASLKS  291

Query  303  DMA----TMEKKGVPTGRYVVNPLNGDKLEVWIANYVLWGYGDGAVMAVPAHDERDFEFA  358
            D+A    + EK GV TG Y +NP+NG  + VWIA+YVL +YG GA+MAVPAHDERD EFA
Sbjct  292  DLARTDLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFA  351

Query  359  AKYNLPKKQVI---AVGDNAFDANRWQEWYGDKENGVLVNSGDLDGLDFQTAFDAVAAKL  415
             ++NL    V+    V + AF            E+G+ +NS+ LDGLD  +A+  +   L
Sbjct  352  KQFNLDIIPVLEGGNVEEAAF-----------TEDGLHINSDFLDGLDKASAIAKMVEWL  400

Query  416  QSQGAGEPKTQYRLRDWGISRQRYWGCPIPIVHCEKCGDVPVPADQLPVVLP--ENVVPD  473
            +++G G+ +  YRLRDW +SRQRYWG PIPI+H E     +VP  +LP+VLP   ++ P 
Sbjct  401  EAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPS  460

Query  474  GMG-SPLAKMPEFYETSCPCCGGAAKRETDTMDTFMESSWYFFRYMSPKFSDGMVSAESA  532
            G G SPLA++ +  E +    G  ++RET+TM     SSWY++RY+ P  ++ +   E  
Sbjct  461  GTGESPLANVTDWLEVTRE-DGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELL  519

Query  533  KYWGAVDQYIGGIEHAILHLLYARFFTKLMRDEGLVNVDEPFERLLTQGMVVCETYYREN  592
            K W +VD Y+GG EHA+LHLLYARF  K++ D G+V   EPF++L+ QGM++  +Y   +
Sbjct  520  KQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY--RD  577

Query  593  DKGGKDWINPADVELTFDDKGRPVSAVLKADGLPVVISGTEKMSKSKNNGVDPQELINAY  652
             +G+   +    VE       +  ++ +  +    +  +  KMSKS +N V+P+++++ Y
Sbjct  578  SRGAL--VATDKVE-------KRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQY  628

Query  653  GADTARLFMMFAAPPEQSLEWSDSGVEGAHRFLRRLWRTVYEYLKQGGAVKAFAGNQDGL  712
            GADT R++ MF +P + S+ WS+ G+EG+++FL R+ R +        + K ++ ++ G 
Sbjct  629  GADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLI--------TTKEITEENSG-  679

Query  713  SKELKDLRHKLHSTTAKVSDDYGRRQQFNTAIAAVMELLNQYDKTDTGSEQGRAVAQEVL  772
               L    +K+ + T K   +   + +FNTAIA +M ++N  +K D        +  +  
Sbjct  680  --AL----DKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK-------LFSDYA  726

Query  773  EAAVRLLWPIVPHICETLWSEL--NGAKLWEAGWPTVDEAALVKSEIEVMVQVNGKLRGK  830
             + V+L+ P+ PH+ E LW  L  +G  +    WP+ DE+ LV +++E++VQ++GK+++K
Sbjct  727  KGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAK  786

Query  831  ITvaadaskadleaaalanegavkFMEGKPAKKIIVVPGRLVNIVV  876
            + VA D S+ +L+  ALANE     + GK   K+I VP +LVNIV+
Sbjct  787  LVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

1689) XNR_4367 in NC_020990


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  484 bits (1823),  Expect = 2e-137, Method: Compositional matrix adjust.
 Identities = 363/744 (49%), Positives = 495/744 (67%), Gaps = 64/744 (8%)

Query  224  LAYASDAPVNWAPGLGTVLANEEVTSEGRSERGNFPVFKAKLRQWNMRITAYAdrllddl  283
            LAY ++ PVNW   LGT +ANEEV ++G SERG +PV +  +RQW ++ITAYA+RLL+DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  284  dgldWPEAIKLQQRNWIGRSEGARVDFPFDGEHTGKAVTVFTTRQDTLFGATYMVLAPEH  343
            + +DWPE+IK  QRNWIG+S GA V   F   +T+K  TVFTTR DTLFGATY VLAPEH
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANV--TFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEH  265

Query  344  ELVDEIVPAAWPDGTRESWTGGHATPAEAVEKYRAFAAGKSDVERQADAKEKTGVFTGAY  403
             LVD I  +                 AEAV  Y+  A+ KSD+ R   AKEKTGV TG+Y
Sbjct  266  ALVDAITTSD---------------QAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSY  310

Query  404  AVNPVSGEHVPVFIADYVLMGYGTGAIMAVPAHDSRDFAFARAFDLPIRCVVEPTDGRST  463
            A+NPV+G ++PV IADYVL +YGTGAIMAVPAHD RD  FA+ F+L I  V+E  +    
Sbjct  311  AINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVE--  368

Query  464  DPLTWDDAFNAYDAQLMASANAEVSLDGLDVATAKARITGWLRERGIGEGTVNFRLRDWL  523
                 + AF   +  L  +++    LDGLD A+A A++  WL   G+G+  V +RLRDWL
Sbjct  369  -----EAAFT--EDGLHINSD---FLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWL  418

Query  524  FSRQRYWGEPFPIVYDEDGVAHAlpesmlplelpeVDDYSPRTFDPDDADTQPETPLSRN  583
            FSRQRYWGEP+PI+  EDG + A+PES LPL LP   D  P            E+PL+  
Sbjct  419  FSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANV  470

Query  584  EDWVNVTLDLGDGPKKYRRETNTMPNWAGSCWYELRYLDPHNDQRLVDPEIEKYWMGPRE  643
             DW++VT +  DG K  RRETNTMP+WAGS WY LRY+DPHN ++L D E+ K W+    
Sbjct  471  TDWLEVTRE--DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLP---  524

Query  644  GMPGGGVDLYIGGAEHAVLHLLYARFWSKVLFDLGYISSSEPFHKLYNQGMIQAYVYRDS  703
                  VD+Y+GGAEHAVLHLLYARFW KVL+DLG +++ EPF+KL+NQGMI +  YRDS
Sbjct  525  ------VDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDS  578

Query  704  RGIPVPAAEVEERDGTFWYQ---GEQVSRLLGKMGKSLKNAVTPDEICAEYGADTLRLYE  760
            RG  V++  VE RDG+F ++   GE++ +  +KM+KSLKN V PD++  +YGADTLR+YE
Sbjct  579  RGALVATDKVEKRDGSF-FHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYE  637

Query  761  MAMGPLDVSRPWDTRAVVGQYRLLQRLWRNVVDEATGEVSVVDVPEAEAGTDTLRALNKA  820
            M MGPLD S +W   ++ G  ++L+R+ R +           ++ E ++G+   +  N +
Sbjct  638  MFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTK--------EITEENSGALD-KVYNET  688

Query  821  IDGVTQDMAALRFNTAIAKVTELNNFLTKADRPVPRPVAEKLVLLIAPLAPHIAEELWRR  880
            + +VT+++  ++FNTAIA++  + N   K D+  +   A  +V LIAP+APH++EELW+ 
Sbjct  689  VKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFS-DYAKGFVQLIAPFAPHLGEELWQA  747

Query  881  L-GHQDSVVHQELPVADPAYLVDETVTCVVQIKGKVKARLEVSPSVSeadleqaaladeR  939
            L +  +S+     P  D + LV++ V  VVQIKGKVKA+L V+  +S  +L++ ALA+E+
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  940  VQAALGGAGVRKVIVRAPKLVNIV  963
            VQA ++G ++ KVI  + KLVNIV
Sbjct  808  VQAEIAGKDIIKVIAVPNKLVNIV  831


 Score =  142 bits (521),  Expect = 1e-34, Method: Compositional matrix adjust.
 Identities = 77/150 (52%), Positives = 103/150 (69%), Gaps = 10/150 (6%)

Query  26   AEIEPRWQDFWDAEGTYEAPNPTGELAGDPELVARPKKFIMDMFPYPSGAGLHVGHPLGY  85
            + IEP+WQ FW  + T+ +   +          ++PK + +DMFPYPSGAGLHVGHP GY
Sbjct  7    TAIEPKWQAFWADNHTFKTGTDA----------SKPKFYALDMFPYPSGAGLHVGHPEGY  56

Query  86   IATDVYARFQRMTGHNVLHTLGFDAFGLPAEQYAVQTGTHPRTSTEANMANMRSQLRRLG  145
             ATD+ +RF+R  GHNVLH +G DAFGLPAEQYA++TG +P   T  N+AN + Q+  LG
Sbjct  57   TATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALG  116

Query  146  LGHDNRRSFATIDPEYYKWTQWIFLKIFNS  175
            ++ D  R   T DP+YYKWTQWIF K+++ 
Sbjct  117  FSYDWDREVNTTDPNYYKWTQWIFTKLYEK  146

1690) leuS in NC_009953


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  484 bits (1823),  Expect = 2e-137, Method: Compositional matrix adjust.
 Identities = 339/738 (46%), Positives = 486/738 (66%), Gaps = 59/738 (7%)

Query  219  LAYVSQAPVNWCPGLGTVLANEEVTADGRSERGNFPVFKRNLKQWMMRITAYGdrllddl  278
            LAY ++ PVNW   LGT +ANEEV +DG SERG +PV ++ ++QWM++ITAY++RLL+DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  279  dkldWPEPIKLMQRNWIGRSIGAHIEFPTSAGDSSAVGEPRINVFTTRPDTIFGATYLVL  338
            + +DWPE+IK MQRNWIG+S GA++ F     D        + VFTTRPDT+FGATY VL
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKD------FTVFTTRPDTLFGATYAVL  261

Query  339  APEHALVDDLVPTAWPSGTRDAWTGGQASPraavagyrkvaaakTDMERQAETKEKTGVF  398
            APEHALVD +             T++QA +   VA+Y++ A+ K+D+ R   +KEKTGV 
Sbjct  262  APEHALVDAIT------------TSDQAEA---VADYKRQASLKSDLARTDLAKEKTGVW  306

Query  399  IGAYATNPVTGAQIPIFIADYVLAGYGTGAIMAVPGQDERDWAFAEVFDLPIVRTVRPAE  458
             G+YA NPV G ++P+ IADYVLA+YGTGAIMAVP++DERDW FA  F+L I+  +  ++
Sbjct  307  TGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGN  366

Query  459  GFDGKAYTGEGPAINSAAPERGLNLDGLGVAEAKARTTAWLEASGHGSGAVTYRLRDWLF  518
              +  A+T +G  INS        LDGL+ A A A+   WLEA G G+  VTYRLRDWLF
Sbjct  367  V-EEAAFTEDGLHINSDF------LDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLF  419

Query  519  SRQRYWGEPFPIVYDETGAAIALPEDMLPVELPEVDDFSPRTFDPADAGSNPETPLSRRR  578
            SRQRYWGEP+PI+  E G++ A+PE  LP+ LP   D+ P        ++  E+PL+   
Sbjct  420  SRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVT  471

Query  579  DWVEVELDLGDGPKRYTRETNVMPQWAGSCWYELRYLDPTNADRFVDPDTERYWMGPRGE  638
            DW+EV  + G   +   RETN MPQWAGS WY LRY+DP N++++ D +  + W+     
Sbjct  472  DWLEVTREDGVKGR---RETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWL-----  523

Query  639  GDCGGTDLYVGGAEHAVLHLLYARFWHKVLYDLGHVSSFEPFRKLFNQGYIQAYAYTDAR  698
                  D+YVGGAEHAVLHLLYARFWHKVLYDLG V++ EPF+KLFNQG I + +Y D+R
Sbjct  524  ----PVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSR  579

Query  699  GAYVPAEEVVERSGAYYLGDV--EVSREYGKMGKSLRNVVTPDEMCAAYGADTFRVYEMS  756
            GA V+++ V  R G+++  +   E+ +  +KM+KSL+NVV PD++   YGADT+RVYEM 
Sbjct  580  GALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMF  639

Query  757  MGPLEVSRPWETRAVVGSFRFLQRVWRAIVDERSGASRVVDAPADEATRRLLHRIVDGVR  816
            MGPL+ S +W   ++ GS +FL+RV R I      +++ +      A  ++ +  V +V 
Sbjct  640  MGPLDASIAWSEEGLEGSRKFLDRVYRLI------TTKEITEENSGALDKVYNETVKAVT  693

Query  817  GDMEAMRFNTSVAKLIELTNALTRLPATPREVAEPLVLMVAPFAPHVAEELWRRMGHPT-  875
             +++ M+FNT++A+L+ + NA  +      + A  +V ++APFAPH++EELW+ +  +  
Sbjct  694  EQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGE  753

Query  876  SLAYADFPVADPDLLVAESVTYPVQVNGKVRGRVQVPADAS--eevvraaaldavatale  933
            S++Y   P  D   LV + V   VQ++GKV++++ V+ D S  E    A A + V + + 
Sbjct  754  SISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIA  813

Query  934  GREPRKVIVVPGRMVSVV  951
            G++  KVI VP ++V++V
Sbjct  814  GKDIIKVIAVPNKLVNIV  831


 Score =  135 bits (494),  Expect = 2e-32, Method: Compositional matrix adjust.
 Identities = 75/148 (51%), Positives = 104/148 (71%), Gaps = 11/148 (7%)

Query  22   IERRWQDIWEREGTFHAPNPTGPLADPEHPRAGAEKLYVLDMFPYPSGAGLHVGHPLGYI  81
            IE +WQ +W  + TF +       +D+  P     K+Y LDMFPYPSGAGLHVGHP GY 
Sbjct  9    IEPKWQAFWADNHTFKTG------TDASKP-----KFYALDMFPYPSGAGLHVGHPEGYT  57

Query  82   GTDCFARYQRMAGRNVLHAMGFDAFGLPAEQYAVQTGTHPRTTTEANIARYKAQLRRLGL  141
            +TD ++R++R  G+NVLH+MG DAFGLPAEQYA++TG +P   T  NIA +K Q+  LG+
Sbjct  58   ATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGF  117

Query  142  AHDERRSVATIDADFYRWTQWVFLQIYN  169
            + D  R V T D+++Y+WTQW+F ++Y+
Sbjct  118  SYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1691) leuS in NC_017549


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  484 bits (1823),  Expect = 2e-137, Method: Compositional matrix adjust.
 Identities = 362/894 (41%), Positives = 540/894 (61%), Gaps = 75/894 (8%)

Query  5    YQPLEIETQAQNYWKEHQSFLVRELPDKEKFYCLSMFPYPSGK-LHMGHVRNYTIGDVIS  63
            Y+   IE + Q +W ++++F     + K KFY L MFPYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYHRMQGRNVLQPMGWDAFGMPAENAAMKNNVAPAAWTYDNIAYMKSQLDSLGLAIDWSR  123
            R+ R QG+NVL+PMGWDAFG+PAE+ AM     PA  T +NIA  K Q+++LG++ DW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVTTCKPDYYRWEQWLFTRLFEKGVIYRKNGTVNWDPVDQTVLANEQVI-DGRGWRSGAL  182
            EV T  P+YY+W QW+FT+L+EKG+ Y  +  VNW     T +ANE+V+ DG + R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  IEKREIPMYYFKITAYAEELLESLDNLPGWPEQVKTMQRNWIGKSRGMEIGFPYDQASIG  242
            + ++ +    +KITAYAE LLE L+++ +WPE +K MQRNWIGKS G ++ F   ++   
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTD--  240

Query  243  HAGQLKVFTTRPDTLMGATYVAVAAEHPLATQAAQNDPQLQAFIDECKRGGVAEADIA--  300
               ++ VFTTRPDTL GATY  +A+EH+L    + +D Q +A + + KR +   +D+A  
Sbjct  241  --KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSD-QAEA-VADYKRQASLKSDLART  296

Query  301  --TQEKKGMATSLFVEHPLTGDKLPVWVANYVLMNYGEGAVMAVPGHDERDFEFANKFGL  358
              ++EK G+ T+ +  +P+ G  +PVW+A+YVL +YG GA+MAVP+HDERD EFA++F L
Sbjct  297  DLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNL  356

Query  359  PIKQVYQHKRIYTEALRKEFPREIYEYEYFDDKLWKEWYGAKDTGLVINSGEYDGLSFEE  418
             I  V +   +   A+                          + GL INS+  DGL    
Sbjct  357  DIIPVLEGGNVEEAAF-------------------------TEDGLHINSDFLDGLDKAS  391

Query  419  AFDAIGADLEAKGLGQARTQFRLRDWGISRQRYWGCPIPIIHCEACGDVPVPADQlpvvl  478
            A+  +   LEA G+G+    +RLRDW +SRQRYWG PIPIIH E     +VP  +LP+VL
Sbjct  392  AIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVL  451

Query  479  pedvvpdGSG---SPLAKMPEFYECSCPKCGQPAKRETDTMDTFVESSWYFARYACPQFE  535
            P       SG   SPLA++ +  E +    G  ++RET+TM     SSWY+ RY  P+  
Sbjct  452  PVTKDIRPSGTGESPLANVTDWLEVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNT  510

Query  536  GGMLDKKAADYWLPVDQYIGGIEHAILHLLYARFFHKLMRDEGLVGSDEPFKNLLTQGMV  595
              + D      WLPVD Y+GG EHA+LHLLYARF HK++ D G+V + EPF++L+ QGM+
Sbjct  511  EKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMI  570

Query  596  VADTYYRTTANGGKDWFNPADVEVERDAKAKVVGARLKSDGQPVEIGGTEKMSKSKNNGV  655
            ++ + YR          ++ +  V  D   K  G+ +  +       +  KMSKS +N V
Sbjct  571  LGTS-YR----------DSRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVV  619

Query  656  DPQSMIDQYGADTCRLFMMFASPPDMSLEWSDAGVEGANRFLRRVWRLAHA-HVSAGLPG  714
            +P+ +++QYGADT R++ MF +P D S+ WS+ G+EG+ +FL RV RL  + +++   +G
Sbjct  620  NPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITEENSG  679

Query  715  ALDVAALNDAQKQVRRAIHLAIRQASQDVGQHHKFNTAIAAVMTLMNVLEKAPNQDAQDR  774
            ALD            +  + +++  +++V ++ KFNTAIA +M ++N  +K       + 
Sbjct  680  ALD------------KVYNETVKAVTEQV-DQMKFNTAIAQLMVFVNAANK-------ED  719

Query  775  ALIQEGLETVVLLLAPITPHICHVLWGQLGHAEAVID-ARWPSVDESAlvqdtlqlvvqv  833
             L+ +     V L+AP++PH+ + LW  L  +   I    WPS DES LV++ +++VVQ+
Sbjct  720  KLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQI  779

Query  834  NGKLRGHIDVAASASREDVEAAARANENVLRFTEGLSIRKVIVVPGKLVNIVAN  887
            +GK+++ + VA   SRE+++  A ANE+V     G  I KVI VP KLVNIV +
Sbjct  780  KGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

1692) leuS in NC_002946


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  484 bits (1826),  Expect = 8e-138, Method: Compositional matrix adjust.
 Identities = 361/886 (41%), Positives = 540/886 (61%), Gaps = 71/886 (8%)

Query  7    YQPAAIEPAAQKKWDDARISNVSEDASKPKYYCLSMFPYPSGK-LHMGHVRNYTIGDVLS  65
            Y+ +AIEP  Q  W D +  + + DASKPK+Y L MFPYPSG  LH+GH   YT  D+LS
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  66   RFKLLNGFNVMQPMGWDAFGMPAENAAMKNNVAPAAWTYDNIEYMKTQLKSLGFAIDWER  125
            RFK  +G NV++PMGWDAFG+PAE+ AM     PA  T +NI   K Q+++LGF+ DW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  126  EVATCKPEYYRWEQWLFTKLFEKGIVYRKNGTVNWDPVDQTVLANEQVI-DGRGWRSGAL  184
            EV T  P+YY+W QW+FTKL+EKG+ Y  +  VNW     T +ANE+V+ DG + R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  185  IEKREIPMYYFKITDYAEELLNDLDKLEHWPEQVKTMQRNWIGKSRGMTVRFAVSDDSKQ  244
            + ++ +    +KIT YAE LL+DL+ ++ WPE +K MQRNWIGKS G  V F V D  K+
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  245  GLEGDYAKFLQVYTTRPDTLMGATYVavaaehplataaaaDKPELQAFIAECKAGSVAEA  304
                     + V+TTRPDTL GATY         A   A   ++    +A+ K  +   +
Sbjct  243  ---------FTVFTTRPDTLFGATYA--VLAPEHALVDAITTSDQAEAVADYKRQASLKS  291

Query  305  DMA----TMEKKGVPTGRYVVNPLNGDKLEVWIANYVLWGYGDGAVMAVPAHDERDFEFA  360
            D+A    + EK GV TG Y +NP+NG  + VWIA+YVL +YG GA+MAVPAHDERD EFA
Sbjct  292  DLARTDLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFA  351

Query  361  AKYNLPKKQVI---AVGDNAFDANRWQEWYGDKENGVLVNSGDLDGLDFQTAFDAVAAKL  417
             ++NL    V+    V + AF            E+G+ +NS+ LDGLD  +A+  +   L
Sbjct  352  KQFNLDIIPVLEGGNVEEAAF-----------TEDGLHINSDFLDGLDKASAIAKMVEWL  400

Query  418  QSQGAGEPKTQYRLRDWGISRQRYWGCPIPIVHCEKCGDVPVPADQLPVVLP--ENVVPD  475
            +++G G+ +  YRLRDW +SRQRYWG PIPI+H E     +VP  +LP+VLP   ++ P 
Sbjct  401  EAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPS  460

Query  476  GMG-SPLAKMPEFYETSCPCCGGAAKRETDTMDTFMESSWYFFRYMSPKFSDGMVSAESA  534
            G G SPLA++ +  E +    G  ++RET+TM     SSWY++RY+ P  ++ +   E  
Sbjct  461  GTGESPLANVTDWLEVTRE-DGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELL  519

Query  535  KYWGAVDQYIGGIEHAILHLLYARFFTKLMRDEGLVNVDEPFERLLTQGMVVCETYYREN  594
            K W +VD Y+GG EHA+LHLLYARF  K++ D G+V   EPF++L+ QGM++  +Y   +
Sbjct  520  KQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY--RD  577

Query  595  DKGGKDWINPADVELTFDDKGRPVSAVLKADGLPVVISGTEKMSKSKNNGVDPQELINAY  654
             +G+   +    VE       +  ++ +  +    +  +  KMSKS +N V+P+++++ Y
Sbjct  578  SRGAL--VATDKVE-------KRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQY  628

Query  655  GADTARLFMMFAAPPEQSLEWSDSGVEGAHRFLRRLWRTVYEYLKQGGAVKAFAGNQDGL  714
            GADT R++ MF +P + S+ WS+ G+EG+++FL R+ R +        + K ++ ++ G 
Sbjct  629  GADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLI--------TTKEITEENSG-  679

Query  715  SKELKDLRHKLHSTTAKVSDDYGRRQQFNTAIAAVMELLNQYDKTDTGSEQGRAVAQEVL  774
               L    +K+ + T K   +   + +FNTAIA +M ++N  +K D        +  +  
Sbjct  680  --AL----DKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK-------LFSDYA  726

Query  775  EAAVRLLWPIVPHICETLWSEL--NGAKLWEAGWPTVDEAALVKSEIEVMVQVNGKLRGK  832
             + V+L+ P+ PH+ E LW  L  +G  +    WP+ DE+ LV +++E++VQ++GK+++K
Sbjct  727  KGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAK  786

Query  833  ITvaadaskadleaaalanegavkFMEGKPAKKIIVVPGRLVNIVV  878
            + VA D S+ +L+  ALANE     + GK   K+I VP +LVNIV+
Sbjct  787  LVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

1693) BLIJ_1032 in NC_017219


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  483 bits (1822),  Expect = 2e-137, Method: Compositional matrix adjust.
 Identities = 334/754 (45%), Positives = 476/754 (64%), Gaps = 73/754 (9%)

Query  234  LAYISKSPVNWCPGLGTVLANEEVTAEGKSERGNFPVFQRELRQWSMRITKYGHRLIADL  293
            LAY +  PVNW   LGT +ANEEV ++G SERG +PV ++ +RQW ++IT Y++RL+ DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  294  DGIDWPEKVKLMQRNWIGESHGASVHFTVATADGDKDMEIYTTRPDTLFGTTFAVVSPEH  353
            + +DWPE +K MQRNWIG S GA+V F V   D DKD  ++TTRPDTLFG+T+AV++PEH
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKV--KDTDKDFTVFTTRPDTLFGATYAVLAPEH  265

Query  354  HLLENVPAEWPADVPEDWKGGYVNPVEAVKAYRLAAEAKTAKDRVDEGGEKTGLFTGLYA  413
             L++ + +               +  EAV  Y+  A  K+   R D + EKTG+ TG YA
Sbjct  266  ALVDAITTS--------------DQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYA  311

Query  414  TNPITGAKLPLFTADYVLMDYGTGAIMAVPGGDQRDYDFAVKFGLPVIYTVKPLPDSGDD  473
             NP+ G  +P+  ADYVL  YGTGAIMAVP+ D+RD +FA +F L +I    P+ ++G+ 
Sbjct  312  INPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDII----PVLEGGN-  366

Query  474  LANYEGKAPFVSHDGIVINSHVESTYAKGDALSLDGLRVDDAIAKVNAWLEDAGVGKGTV  533
                   A+F ++DG+    H++S +       LDGL    AIAK+  WLE  GVG+  V
Sbjct  367  ----VEEAAF-TEDGL----HINSDF-------LDGLDKASAIAKMVEWLEAEGVGNENV  410

Query  534  SYRLRDWLFSRQRYWGEPFPIVYGEDGTPHLLPDSALPISLPDVPDYEPRTFDPMDAESN  593
            +YRLRDWLFSRQRYWGEP+PI+  EDGT+  +P+S LP+ LP   D  P         + 
Sbjct  411  TYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGT  462

Query  594  PEAPLSRNEDWVKVELDLGDGKKTYYRDTNTMPNWAGSCWYYMRYIDPTDTKHMVEKDEF  653
             E+PL+   DW+ V  + G   +   R+TNTMP+WAGS WYY+RYIDP +T  + + + +
Sbjct  463  GESPLANVTDWLEVTREDGVKGR---RETNTMPQWAGSSWYYLRYIDPHNTEKLADEELL  519

Query  654  DYWMGPNHNKYSGDEGGVDLYIGGVEHAVLHLLYSRFWHKVLFDLGYVDSAEPFHKLFNQ  713
              W+             VD+Y+GG EHAVLHLLY+RFWHKVL+DLG V + EPF+KLFNQ
Sbjct  520  KQWL------------PVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQ  567

Query  714  GMIQAYAYTDDRGQYVPADEVVEGPADASGEPTFTWNGEHANREFGKMGKSLKNIVTPDY  773
            GMI + +Y D RG  V++D V    +      T    GE+ ++  +KM+KSLKN+V PD 
Sbjct  568  GMILGTSYRDSRGALVATDKVEKRDGSFFHVET----GEELEQAPAKMSKSLKNVVNPDD  623

Query  774  MYENYGADTFRLYEMSMGPLDESRPWNTRNVVGGMRFLQRLWRNVVDETTGQAHVTEDAP  833
            + E+YGADT+R+YEM MGPLD S +W+   + G+ +FL+R+ R +        ++TE+ +
Sbjct  624  VVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTK-----EITEENS  678

Query  834  DEKTLKLLNNTIAEVTAEMEGMRPNTAIAKLIVLNNHLTGLKAVPRAAVEPLVLMLAPIA  893
            +    K+ N+T+  VT +++ M+ NTAIA+L+V+ N       +       +V ++AP+A
Sbjct  679  GALD-KVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFA  737

Query  894  PHICEEMWSKL-GHPESLSAEPWPVADERYVGHDTVTAVVQIKGKVRAKLEVPVDIDPAD  952
            PH+ EE+W  L +  ES+S  PWP  DE  + ++ V  VVQIKGKV+AKL V+ D+   +
Sbjct  738  PHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREE  797

Query  953  LKKQALAA--VADRLGGKEPRKVIVKAPKIVSIV  984
            L+  ALA   V   ++GK+  KVI  + K+V+IV
Sbjct  798  LQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIV  831


 Score =  135 bits (496),  Expect = 1e-32, Method: Compositional matrix adjust.
 Identities = 74/150 (50%), Positives = 103/150 (69%), Gaps = 12/150 (8%)

Query  25   IENKWQKIWDEQGTFWAANVNGDLKDGKGRNAEGRTAYFAMDMFPYPSGKGLHVGHPLGY  84
            IE KWQ +W ++ TF            K     ++  ++A+DMFPYPSG GLHVGHP GY
Sbjct  9    IEPKWQAFWADNHTF------------KTGTDASKPKFYALDMFPYPSGAGLHVGHPEGY  56

Query  85   LASDVTSRYHRMKGENVLHAMGYDAFGLPAEQYAVQTGQHPRVTTEANIANMSRQLHRMG  144
             A+D+ SR+ R +G+NVLH+MG DAFGLPAEQYA++TG++P   T  NIAN  RQ++ +G
Sbjct  57   TATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALG  116

Query  145  LGFDNRRTFATIDPGYMRWTQWIFSRIYDS  174
            +++D  R   T DP Y +WTQWIF+++Y+ 
Sbjct  117  FSYDWDREVNTTDPNYYKWTQWIFTKLYEK  146

1694) leuS in NC_011593


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  483 bits (1822),  Expect = 2e-137, Method: Compositional matrix adjust.
 Identities = 334/754 (45%), Positives = 476/754 (64%), Gaps = 73/754 (9%)

Query  234  LAYISKSPVNWCPGLGTVLANEEVTAEGKSERGNFPVFQRELRQWSMRITKYGHRLIADL  293
            LAY +  PVNW   LGT +ANEEV ++G SERG +PV ++ +RQW ++IT Y++RL+ DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  294  DGIDWPEKVKLMQRNWIGESHGASVHFTVATADGDKDMEIYTTRPDTLFGTTFAVVSPEH  353
            + +DWPE +K MQRNWIG S GA+V F V   D DKD  ++TTRPDTLFG+T+AV++PEH
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKV--KDTDKDFTVFTTRPDTLFGATYAVLAPEH  265

Query  354  HLLENVPAEWPADVPEDWKGGYVNPVEAVKAYRLAAEAKTAKDRVDEGGEKTGLFTGLYA  413
             L++ + +               +  EAV  Y+  A  K+   R D + EKTG+ TG YA
Sbjct  266  ALVDAITTS--------------DQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYA  311

Query  414  TNPITGAKLPLFTADYVLMDYGTGAIMAVPGGDQRDYDFAVKFGLPVIYTVKPLPDSGDD  473
             NP+ G  +P+  ADYVL  YGTGAIMAVP+ D+RD +FA +F L +I    P+ ++G+ 
Sbjct  312  INPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDII----PVLEGGN-  366

Query  474  LANYEGKAPFVSHDGIVINSHVESTYAKGDALSLDGLRVDDAIAKVNAWLEDAGVGKGTV  533
                   A+F ++DG+    H++S +       LDGL    AIAK+  WLE  GVG+  V
Sbjct  367  ----VEEAAF-TEDGL----HINSDF-------LDGLDKASAIAKMVEWLEAEGVGNENV  410

Query  534  SYRLRDWLFSRQRYWGEPFPIVYGEDGTPHLLPDSALPISLPDVPDYEPRTFDPMDAESN  593
            +YRLRDWLFSRQRYWGEP+PI+  EDGT+  +P+S LP+ LP   D  P         + 
Sbjct  411  TYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGT  462

Query  594  PEAPLSRNEDWVKVELDLGDGKKTYYRDTNTMPNWAGSCWYYMRYIDPTDTKHMVEKDEF  653
             E+PL+   DW+ V  + G   +   R+TNTMP+WAGS WYY+RYIDP +T  + + + +
Sbjct  463  GESPLANVTDWLEVTREDGVKGR---RETNTMPQWAGSSWYYLRYIDPHNTEKLADEELL  519

Query  654  DYWMGPNHNKYSGDEGGVDLYIGGVEHAVLHLLYSRFWHKVLFDLGYVDSAEPFHKLFNQ  713
              W+             VD+Y+GG EHAVLHLLY+RFWHKVL+DLG V + EPF+KLFNQ
Sbjct  520  KQWL------------PVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQ  567

Query  714  GMIQAYAYTDDRGQYVPADEVVEGPADASGEPTFTWNGEHANREFGKMGKSLKNIVTPDY  773
            GMI + +Y D RG  V++D V    +      T    GE+ ++  +KM+KSLKN+V PD 
Sbjct  568  GMILGTSYRDSRGALVATDKVEKRDGSFFHVET----GEELEQAPAKMSKSLKNVVNPDD  623

Query  774  MYENYGADTFRLYEMSMGPLDESRPWNTRNVVGGMRFLQRLWRNVVDETTGQAHVTEDAP  833
            + E+YGADT+R+YEM MGPLD S +W+   + G+ +FL+R+ R +        ++TE+ +
Sbjct  624  VVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTK-----EITEENS  678

Query  834  DEKTLKLLNNTIAEVTAEMEGMRPNTAIAKLIVLNNHLTGLKAVPRAAVEPLVLMLAPIA  893
            +    K+ N+T+  VT +++ M+ NTAIA+L+V+ N       +       +V ++AP+A
Sbjct  679  GALD-KVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFA  737

Query  894  PHICEEMWSKL-GHPESLSAEPWPVADERYVGHDTVTAVVQIKGKVRAKLEVPVDIDPAD  952
            PH+ EE+W  L +  ES+S  PWP  DE  + ++ V  VVQIKGKV+AKL V+ D+   +
Sbjct  738  PHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREE  797

Query  953  LKKQALAA--VADRLGGKEPRKVIVKAPKIVSIV  984
            L+  ALA   V   ++GK+  KVI  + K+V+IV
Sbjct  798  LQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIV  831


 Score =  135 bits (496),  Expect = 1e-32, Method: Compositional matrix adjust.
 Identities = 74/150 (50%), Positives = 103/150 (69%), Gaps = 12/150 (8%)

Query  25   IENKWQKIWDEQGTFWAANVNGDLKDGKGRNAEGRTAYFAMDMFPYPSGKGLHVGHPLGY  84
            IE KWQ +W ++ TF            K     ++  ++A+DMFPYPSG GLHVGHP GY
Sbjct  9    IEPKWQAFWADNHTF------------KTGTDASKPKFYALDMFPYPSGAGLHVGHPEGY  56

Query  85   LASDVTSRYHRMKGENVLHAMGYDAFGLPAEQYAVQTGQHPRVTTEANIANMSRQLHRMG  144
             A+D+ SR+ R +G+NVLH+MG DAFGLPAEQYA++TG++P   T  NIAN  RQ++ +G
Sbjct  57   TATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALG  116

Query  145  LGFDNRRTFATIDPGYMRWTQWIFSRIYDS  174
            +++D  R   T DP Y +WTQWIF+++Y+ 
Sbjct  117  FSYDWDREVNTTDPNYYKWTQWIFTKLYEK  146

1695) leuS in NC_008611


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  483 bits (1820),  Expect = 3e-137, Method: Compositional matrix adjust.
 Identities = 338/742 (46%), Positives = 507/742 (69%), Gaps = 56/742 (7%)

Query  237  DHRLVYRADSMVNWCPGLGTVLANEEVTSDGRSDRGNFPVFRKRLRQWMMRITAYSdrll  296
            +  L Y A+  VNW   LGT +ANEEV +DG S+RG +PV RK +RQWM++ITAY++RLL
Sbjct  145  EKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLL  204

Query  297  ddldvldwpdQVKTMQRNWIGRSTGASALFTATRSNGETVGLEVFTTRPDTLFGATYLVL  356
            +DL+ +DWP+ +K MQRNWIG+STGA+  F    ++ +   + VFTTRPDTLFGATY VL
Sbjct  205  EDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKD---FTVFTTRPDTLFGATYAVL  261

Query  357  APEHDLVDDLVGAGWPAGVDPLWTGGGatpaeavaayrraiaVKSDLERQE-SKEKTGVF  415
            APEH LVD +  ++ + +V                  +R  ++KSDL R + +KEKTGV 
Sbjct  262  APEHALVDAITTSDQAEAVADY---------------KRQASLKSDLARTDLAKEKTGVW  306

Query  416  LGSHAINPATGQPVPIFIADYVLAGYGTGAIMAVPGHDQRDWDFARALGLPVVEVIAGGD  475
             GS AINP  G+ +P+ IADYVLA+YGTGAIMAVP+HD+RDW+FA+ + L ++ V+ GG+
Sbjct  307  TGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGN  366

Query  476  ISQAAYTGDGVLVNSGFLDGMSVGEAKQAITARLESDGYGQARIEFKLRDWLFARQRYWG  535
            + +AA+T DG+ +NS+FLDG+  + A   +  +LE++G G+  + ++LRDWLF+RQRYWG
Sbjct  367  VEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWG  426

Query  536  EPFPIVYDADGRPHALDESALPVELPDVPDYSPVLFDPDDANSEPSPPLGKATEWLHVEL  595
            EP+PI+   DG + A+ ES LP+ LP   D  P        ++   +PL++ T+WL+V  
Sbjct  427  EPIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTDWLEVTR  478

Query  596  DLGDGLKPYSRDTNVMPQWAGSSWYELRYTDPHNADRFCAKENETYWMGPRPAEHGPDDP  655
            +  DG+K   R+TN MPQWAGSSWY LRY DPHN++++   E    W+            
Sbjct  479  E--DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWL------------  523

Query  656  GGVDLYVGGAEHAVLHLLYARFWHKVLYDLGHVSSREPYRKLINQGYIQAFAYTDARGSY  715
              VD+YVGGAEHAVLHLLYARFWHKVLYDLG V+++EP++KL+NQG I + +Y D+RG+ 
Sbjct  524  -PVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGAL  582

Query  716  VPAEEVIERDGGFVYPGADGEIEVFQEFGKIGKSLKNSISPDEICDDYGADTLRVYEMSM  775
            V+++ V  RDG+F    ++ E+E  Q  +K++KSLKN ++PD++ ++YGADTLRVYEM M
Sbjct  583  VATDKVEKRDGSFFHVETGEELE--QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFM  640

Query  776  GPIEASRPWATKDVIGAHRFLQRVWRLVIDENTGEILVADTPAELDTDTLRALHRAIAGV  835
            GP++AS +W+  ++ G+++FL+RV RL+   +  E    + ++ LD    +  + ++ +V
Sbjct  641  GPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITE----ENSGALD----KVYNETVKAV  692

Query  836  AEDYAALRNNTAVAKLIEYTNFLTKRHRDAVPRAVIEPLVLMVAPLAPHLAEELWQRLGH  895
            +E+   ++ NTA+A+L+ + N   K ++  +       +V ++AP+APHL+EELWQ L  
Sbjct  693  TEQVDQMKFNTAIAQLMVFVNAANKEDK--LFSDYAKGFVQLIAPFAPHLGEELWQALTA  750

Query  896  TT-SLAHGPFPAADPAYLIDDTVEYPVQVNGKVRGRvvvaadadddavkaaaladqkvqa  954
            +  S++  P P+ D + L+++ VE  VQ++GKV++++VVA D   + ++  ALA++KVQA
Sbjct  751  SGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQA  810

Query  955  FLAGASPRKVIVVAGRLVNLVV  976
             +AG    KVI V+ +LVN+V+
Sbjct  811  EIAGKDIIKVIAVPNKLVNIVI  832


 Score =  132 bits (486),  Expect = 8e-32, Method: Compositional matrix adjust.
 Identities = 73/150 (49%), Positives = 103/150 (69%), Gaps = 11/150 (7%)

Query  41   AGVERTWQQNWARLGTFNVPNPVGSLAPSDGSPVPEDKLFVQDMFPYPSGEGLHVGHPLG  100
            +++E  WQ  WA   TF+            G+  +  K++  DMFPYPSG GLHVGHP G
Sbjct  7    TAIEPKWQAFWADNHTFKT-----------GTDASKPKFYALDMFPYPSGAGLHVGHPEG  55

Query  101  YIATDVFARYHRMKGRNVLHALGFDAFGLPAEQYAVQTGTHPRTRTEANVVNFRRQLGRL  160
            Y ATD+++R+ R +G+NVLH++G DAFGLPAEQYA++TG +P   T  N+ NF+RQ+  L
Sbjct  56   YTATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINAL  115

Query  161  GLGHDSRRSFSTTDVEFYKWTQWIFLQIYN  190
            G++ D  R  +TTD ++YKWTQWIF ++Y+
Sbjct  116  GFSYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1696) leuS in NC_014169


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  483 bits (1820),  Expect = 3e-137, Method: Compositional matrix adjust.
 Identities = 332/754 (45%), Positives = 476/754 (64%), Gaps = 73/754 (9%)

Query  234  LAYISKSPVNWCPGLGTVLANEEVTAEGKSERGNFPVFQRELRQWSMRITKYGHRLIADL  293
            LAY +  PVNW   LGT +ANEEV ++G SERG +PV ++ +RQW ++IT Y++RL+ DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  294  DGINWPEKVKLMQRNWIGESHGASVHFTVATADGDKDMEIYTTRPDTLFGTTFAVVSPEH  353
            + ++WPE +K MQRNWIG S GA+V F V   D DKD  ++TTRPDTLFG+T+AV++PEH
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKV--KDTDKDFTVFTTRPDTLFGATYAVLAPEH  265

Query  354  HLLENVPAEWPADVPEDWKGGYVNPVEAVKAYRLAAEAKTAKDRVDEGGEKTGLFTGLYA  413
             L++ + +               +  EAV  Y+  A  K+   R D + EKTG+ TG YA
Sbjct  266  ALVDAITTS--------------DQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYA  311

Query  414  TNPITGAKLPLFTADYVLMDYGTGAIMAVPGGDQRDYDFAVKFGLPVIYTVKPLPDSGDD  473
             NP+ G  +P+  ADYVL  YGTGAIMAVP+ D+RD +FA +F L +I    P+ ++G+ 
Sbjct  312  INPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDII----PVLEGGN-  366

Query  474  LANYEGKAPFVSHDGIVINSHVESTYAKGDALSLDGLRVDDAIAKVNAWLENAGVGKGAV  533
                   A+F ++DG+    H++S +       LDGL    AIAK+  WLE  GVG+  V
Sbjct  367  ----VEEAAF-TEDGL----HINSDF-------LDGLDKASAIAKMVEWLEAEGVGNENV  410

Query  534  SYRLRDWLFSRQRYWGEPFPIVYGEDGTPHLLPDSALPINLPDVPDYEPRTFDPMDAESN  593
            +YRLRDWLFSRQRYWGEP+PI+  EDGT+  +P+S LP+ LP   D  P         + 
Sbjct  411  TYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGT  462

Query  594  PEAPLSRNEDWVKVELDLGDGKKTYYRDTNTMPNWAGSCWYYMRYIDPTDTKHMVEKDEF  653
             E+PL+   DW+ V  + G   +   R+TNTMP+WAGS WYY+RYIDP +T  + + + +
Sbjct  463  GESPLANVTDWLEVTREDGVKGR---RETNTMPQWAGSSWYYLRYIDPHNTEKLADEELL  519

Query  654  DYWMGPNHNKYSGDEGGVDLYIGGVEHAVLHLLYSRFWHKVLFDLGYVDSAEPFHKLFNQ  713
              W+             VD+Y+GG EHAVLHLLY+RFWHKVL+DLG V + EPF+KLFNQ
Sbjct  520  KQWL------------PVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQ  567

Query  714  GMIQAYAYTDDRGQYVPADEVVEGPADASGEPTFTWNGEHANREFGKMGKSLKNIVTPDY  773
            GMI + +Y D RG  V++D V    +      T    GE+ ++  +KM+KSLKN+V PD 
Sbjct  568  GMILGTSYRDSRGALVATDKVEKRDGSFFHVET----GEELEQAPAKMSKSLKNVVNPDD  623

Query  774  MYENYGADTFRLYEMSMGPLDESRPWNTRNVVGGMRFLQRLWRNVVDETTGEAHVTEDAP  833
            + E+YGADT+R+YEM MGPLD S +W+   + G+ +FL+R+ R +        ++TE+ +
Sbjct  624  VVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTK-----EITEENS  678

Query  834  DEKTLKLLNNTIAEVTAEMEGMRPNTAIAKLIVLNNHLTGLKAVPRAAVEPLILMLAPIA  893
            +    K+ N+T+  VT +++ M+ NTAIA+L+V+ N       +       ++ ++AP+A
Sbjct  679  GALD-KVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFA  737

Query  894  PHICEEMWSKL-GHPESLSAEPWPVADERYVGHDTVTAVVQIKGKVRAKLEVPVDIDPAD  952
            PH+ EE+W  L +  ES+S  PWP  DE  + ++ V  VVQIKGKV+AKL V+ D+   +
Sbjct  738  PHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREE  797

Query  953  LEKQALAA--VADRLGGKEPRKVIVKAPKIVSIV  984
            L+  ALA   V   ++GK+  KVI  + K+V+IV
Sbjct  798  LQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIV  831


 Score =  136 bits (498),  Expect = 9e-33, Method: Compositional matrix adjust.
 Identities = 75/150 (50%), Positives = 104/150 (70%), Gaps = 12/150 (8%)

Query  25   IENKWQKIWDEQGTFWAANVNGDLKDGKGRNAEGRAAYFAMDMFPYPSGKGLHVGHPLGY  84
            IE KWQ +W ++ TF            K     +++ ++A+DMFPYPSG GLHVGHP GY
Sbjct  9    IEPKWQAFWADNHTF------------KTGTDASKPKFYALDMFPYPSGAGLHVGHPEGY  56

Query  85   LASDVTSRYHRMKGENVLHAMGYDAFGLPAEQYAVQTGQHPRVTTEANIANMSRQLHRMG  144
             A+D+ SR+ R +G+NVLH+MG DAFGLPAEQYA++TG++P   T  NIAN  RQ++ +G
Sbjct  57   TATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALG  116

Query  145  LSFDNRRTFATIDPGYVRWTQWIFSRIYDS  174
            +S+D  R   T DP Y +WTQWIF+++Y+ 
Sbjct  117  FSYDWDREVNTTDPNYYKWTQWIFTKLYEK  146

1697) leuS in NC_008618


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  482 bits (1819),  Expect = 4e-137, Method: Compositional matrix adjust.
 Identities = 334/754 (45%), Positives = 474/754 (63%), Gaps = 73/754 (9%)

Query  237  LAYISKSPVNWCPGLGTVLANEEVTAEGKSERGNFPVFQRELRQWSMRITAYGHRLIEDL  296
            LAY +  PVNW   LGT +ANEEV ++G SERG +PV ++ +RQW ++ITAY++RL+EDL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  297  DTIDWPEKVKLMQRNWIGESHGASVHFDVETPNGVKDMEIYTTRPDTLFGTTFAVVSPEH  356
            + +DWPE +K MQRNWIG S GA+V F V   +  KD  ++TTRPDTLFG+T+AV++PEH
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD--KDFTVFTTRPDTLFGATYAVLAPEH  265

Query  357  HLLEDVPAEWPAETPEDWKGGYATPVEAVKAYRLAAEAKTAKDRVDEAGEKTGLFTGLYA  416
             L++ + +              +   EAV  Y+  A  K+   R D A EKTG+ TG YA
Sbjct  266  ALVDAITT--------------SDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYA  311

Query  417  INPITGAKLPLFTADYVLMDYGTGAIMAVPGGDQRDYDFAVKFGLPVIYTVKPLPESGDD  476
            INP+ G  +P+  ADYVL  YGTGAIMAVP+ D+RD +FA +F L +I    P+ E+G+ 
Sbjct  312  INPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDII----PVLEGGN-  366

Query  477  LANYEGKAPFVSHDGIVINSSIDATKAKGDSLSLDGLRVDEAIDKVNAWLESAGVGKGTV  536
                   A+F ++DG+ INS +           LDGL    AI K+  WLE+ GVG+  V
Sbjct  367  ----VEEAAF-TEDGLHINSDF-----------LDGLDKASAIAKMVEWLEAEGVGNENV  410

Query  537  SYRLRDWLFSRQRYWGEPFPIVYGEDGTPHLLPDEQLPINLPDVPDYSPKTFDPEDAESD  596
            +YRLRDWLFSRQRYWGEP+PI+  EDGT+  +P+ +LP+ LP   D  P         + 
Sbjct  411  TYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPS--------GT  462

Query  597  PEAPLSRNEDWVKVELDLGDGKKTYYRDTNTMPNWAGSCWYYMRYLDPTDTKHMVEKDEF  656
             E+PL+   DW+ V  + G   +   R+TNTMP+WAGS WYY+RY+DP +T  + + + +
Sbjct  463  GESPLANVTDWLEVTREDGVKGR---RETNTMPQWAGSSWYYLRYIDPHNTEKLADEELL  519

Query  657  DYWMGPDHNKTAGKSGGVDLYIGGVEHAVLHLLYSRFWHKVLFDLGYVDSMEPFHKLFNQ  716
              W+             VD+Y+GG EHAVLHLLY+RFWHKVL+DLG V + EPF+KLFNQ
Sbjct  520  KQWL------------PVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQ  567

Query  717  GMIQAYAYTDDRGQYVPAAEVVEGPADANGEPTFTWNGQHANREFGKMGKSLKNIITPDD  776
            GMI + +Y D RG  V++  V    +      T    G++ ++  +KM+KSLKN++ PDD
Sbjct  568  GMILGTSYRDSRGALVATDKVEKRDGSFFHVET----GEELEQAPAKMSKSLKNVVNPDD  623

Query  777  MYENYGADTFRLYEMGMGPLAESRPWNTRNVVGSMRFLQRLWRNVIDETTGEVRVTDGEL  836
            + E+YGADT+R+YEM MGPL  S +W+   + GS +FL+R+ R +      E     G L
Sbjct  624  VVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITE--ENSGAL  681

Query  837  DtktlkllnntIADVTVEMEAMRPNTAIAKLIVLNNHLTSLDAVPRAAVEPLILMLSPIA  896
            D    K+ N+T+  VT +++ M+ NTAIA+L+V+ N     D +       ++ +++P+A
Sbjct  682  D----KVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFA  737

Query  897  PHICEELWSKL-GHTESLAHADWPKADERYVGQDSVTAVVQIKGKVRAKLEVSPDIDPKE  955
            PH+ EELW  L +  ES++   WP  DE  + ++ V  VVQIKGKV+AKL V+ D+   E
Sbjct  738  PHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREE  797

Query  956  LEKMAL--EAVADRLGGKEPRKVIVKAPKIVSIV  987
            L+ +AL  E V   ++GK+  KVI  + K+V+IV
Sbjct  798  LQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIV  831


 Score =  142 bits (523),  Expect = 1e-34, Method: Compositional matrix adjust.
 Identities = 78/150 (52%), Positives = 108/150 (72%), Gaps = 12/150 (8%)

Query  29   GIEEKWQKIWDDEGTFWAANVNGDLKDGKGHNAEGRPSYFAMDMFPYPSGKGLHVGHPLG  88
            +IE KWQ +W D+ TF            K     ++P ++A+DMFPYPSG GLHVGHP G
Sbjct  8    AIEPKWQAFWADNHTF------------KTGTDASKPKFYALDMFPYPSGAGLHVGHPEG  55

Query  89   YLATDVVSRYHRMKGENVLHAMGYDAFGLPAEQYAVQTGQHPRITTEQNIANMRRQLHRM  148
            Y ATD++SR+ R +G+NVLH+MG DAFGLPAEQYA++TG++P   T +NIAN +RQ++ +
Sbjct  56   YTATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINAL  115

Query  149  GLSFDNRRSFATIDPGYVRWTQWIFSRIYD  178
            G+S+D  R   T DP Y +WTQWIF+++Y+
Sbjct  116  GFSYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1698) leuS in NC_014656


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  482 bits (1819),  Expect = 4e-137, Method: Compositional matrix adjust.
 Identities = 332/754 (45%), Positives = 477/754 (64%), Gaps = 73/754 (9%)

Query  234  LAYISKSPVNWCPGLGTVLANEEVTAEGKSERGNFPVFQRELRQWSMRITKYGHRLIADL  293
            LAY +  PVNW   LGT +ANEEV ++G SERG +PV ++ +RQW ++IT Y++RL+ DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  294  DGINWPEKVKLMQRNWIGESHGASVHFTVATADGDKDMEIYTTRPDTLFGTTFAVVSPEH  353
            + ++WPE +K MQRNWIG S GA+V F V   D DKD  ++TTRPDTLFG+T+AV++PEH
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKV--KDTDKDFTVFTTRPDTLFGATYAVLAPEH  265

Query  354  HLLENVPAEWPADVPEDWKGGYANPVEAVKAYRLAAEAKTAKDRVNEAGEKTGLFTGLYA  413
             L++ + +              ++  EAV  Y+  A  K+   R + A EKTG+ TG YA
Sbjct  266  ALVDAITT--------------SDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYA  311

Query  414  TNPITGAKLPLFTADYVLMDYGTGAIMAVPGGDQRDYDFAVKFGLPVIYTVTPLPDSGDD  473
             NP+ G  +P+  ADYVL  YGTGAIMAVP+ D+RD +FA +F L +I    P+ ++G+ 
Sbjct  312  INPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDII----PVLEGGN-  366

Query  474  LANYEGKAPFVSHDGIVINSSVEATEAKGDALSLNGLRVDDAIAKVNAWLESAGVGKGTV  533
                   A+F ++DG+ INS             L+GL    AIAK+  WLE+ GVG+  V
Sbjct  367  ----VEEAAF-TEDGLHINSDF-----------LDGLDKASAIAKMVEWLEAEGVGNENV  410

Query  534  SYRLRDWLFSRQRYWGEPFPIVYGEDGTPHLLPDSALPINLPDVPDYEPRTFDPMDAESN  593
            +YRLRDWLFSRQRYWGEP+PI+  EDGT+  +P+S LP+ LP   D  P         + 
Sbjct  411  TYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGT  462

Query  594  PEAPLSRNEDWVKVELDLGDGKKTYYRDTNTMPNWAGSCWYYMRYIDPTDTKHMVEKDEF  653
             E+PL+   DW+ V  + G   +   R+TNTMP+WAGS WYY+RYIDP +T  + + + +
Sbjct  463  GESPLANVTDWLEVTREDGVKGR---RETNTMPQWAGSSWYYLRYIDPHNTEKLADEELL  519

Query  654  DYWMGPNHNKYSGDEGGVDLYIGGVEHAVLHLLYSRFWHKVLFDLGYVDSAEPFHKLFNQ  713
              W+             VD+Y+GG EHAVLHLLY+RFWHKVL+DLG V + EPF+KLFNQ
Sbjct  520  KQWL------------PVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQ  567

Query  714  GMIQAYAYTDDRGQYVPADEVVEGPADASGEPTFTWNGEHANREFGKMGKSLKNIVTPDY  773
            GMI + +Y D RG  V++D V    +      T    GE+ ++  +KM+KSLKN+V PD 
Sbjct  568  GMILGTSYRDSRGALVATDKVEKRDGSFFHVET----GEELEQAPAKMSKSLKNVVNPDD  623

Query  774  MYENYGADTFRLYEMSMGPLDESRPWNTRNVVGGMRFLQRLWRNVVDETTGQAHVTEDTP  833
            + E+YGADT+R+YEM MGPLD S +W+   + G+ +FL+R+ R +        ++TE+ +
Sbjct  624  VVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTK-----EITEENS  678

Query  834  DEKTLKLLNNTIAEVTAEMEGMRPNTAIAKLIVLNNHLTGLKAVPRAAVEPLILMLAPIA  893
            +    K+ N+T+  VT +++ M+ NTAIA+L+V+ N       +       ++ ++AP+A
Sbjct  679  GALD-KVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFA  737

Query  894  PHICEEMWSKL-GHAESLSAEPWPVADERYVGHDTVTAVVQIKGKVRAKLEVPVDIDPAD  952
            PH+ EE+W  L + +ES+S  PWP  DE  + ++ V  VVQIKGKV+AKL V+ D+   +
Sbjct  738  PHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREE  797

Query  953  LEKQALAA--VADRLGGKEPRKVIVKAPKIVSIV  984
            L+  ALA   V   ++GK+  KVI  + K+V+IV
Sbjct  798  LQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIV  831


 Score =  137 bits (502),  Expect = 5e-33, Method: Compositional matrix adjust.
 Identities = 75/150 (50%), Positives = 104/150 (70%), Gaps = 12/150 (8%)

Query  25   IENKWQKIWDEQGTFWAANVNGDLKDGKGRNAEGRTAYFAMDMFPYPSGKGLHVGHPLGY  84
            IE KWQ +W ++ TF            K     ++  ++A+DMFPYPSG GLHVGHP GY
Sbjct  9    IEPKWQAFWADNHTF------------KTGTDASKPKFYALDMFPYPSGAGLHVGHPEGY  56

Query  85   LASDVVSRYHRMKGENVLHAMGYDAFGLPAEQYAVQTGQHPRVTTEANIANMSRQLHRMG  144
             A+D++SR+ R +G+NVLH+MG DAFGLPAEQYA++TG++P   T  NIAN  RQ++ +G
Sbjct  57   TATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALG  116

Query  145  LSFDNRRTFATIDPGYVRWTQWIFSRIYDS  174
            +S+D  R   T DP Y +WTQWIF+++Y+ 
Sbjct  117  FSYDWDREVNTTDPNYYKWTQWIFTKLYEK  146

1699) leuS in NC_010816


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  482 bits (1819),  Expect = 4e-137, Method: Compositional matrix adjust.
 Identities = 332/754 (45%), Positives = 477/754 (64%), Gaps = 73/754 (9%)

Query  234  LAYISKSPVNWCPGLGTVLANEEVTAEGKSERGNFPVFQRELRQWSMRITKYGHRLIADL  293
            LAY +  PVNW   LGT +ANEEV ++G SERG +PV ++ +RQW ++IT Y++RL+ DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  294  DGINWPEKVKLMQRNWIGESHGASVHFTVATADGDKDMEIYTTRPDTLFGTTFAVVSPEH  353
            + ++WPE +K MQRNWIG S GA+V F V   D DKD  ++TTRPDTLFG+T+AV++PEH
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKV--KDTDKDFTVFTTRPDTLFGATYAVLAPEH  265

Query  354  HLLENVPAEWPADVPEDWKGGYANPVEAVKAYRLAAEAKTAKDRVNEAGEKTGLFTGLYA  413
             L++ + +              ++  EAV  Y+  A  K+   R + A EKTG+ TG YA
Sbjct  266  ALVDAITT--------------SDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYA  311

Query  414  TNPITGAKLPLFTADYVLMDYGTGAIMAVPGGDQRDYDFAVKFGLPVIYTVTPLPDSGDD  473
             NP+ G  +P+  ADYVL  YGTGAIMAVP+ D+RD +FA +F L +I    P+ ++G+ 
Sbjct  312  INPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDII----PVLEGGN-  366

Query  474  LANYEGKAPFVSHDGIVINSSVEATEAKGDALSLNGLRVDDAIAKVNAWLESAGVGKGTV  533
                   A+F ++DG+ INS             L+GL    AIAK+  WLE+ GVG+  V
Sbjct  367  ----VEEAAF-TEDGLHINSDF-----------LDGLDKASAIAKMVEWLEAEGVGNENV  410

Query  534  SYRLRDWLFSRQRYWGEPFPIVYGEDGTPHLLPDSALPINLPDVPDYEPRTFDPMDAESN  593
            +YRLRDWLFSRQRYWGEP+PI+  EDGT+  +P+S LP+ LP   D  P         + 
Sbjct  411  TYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGT  462

Query  594  PEAPLSRNEDWVKVELDLGDGKKTYYRDTNTMPNWAGSCWYYMRYIDPTDTKHMVEKDEF  653
             E+PL+   DW+ V  + G   +   R+TNTMP+WAGS WYY+RYIDP +T  + + + +
Sbjct  463  GESPLANVTDWLEVTREDGVKGR---RETNTMPQWAGSSWYYLRYIDPHNTEKLADEELL  519

Query  654  DYWMGPNHNKYSGDEGGVDLYIGGVEHAVLHLLYSRFWHKVLFDLGYVDSAEPFHKLFNQ  713
              W+             VD+Y+GG EHAVLHLLY+RFWHKVL+DLG V + EPF+KLFNQ
Sbjct  520  KQWL------------PVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQ  567

Query  714  GMIQAYAYTDDRGQYVPADEVVEGPADASGEPTFTWNGEHANREFGKMGKSLKNIVTPDY  773
            GMI + +Y D RG  V++D V    +      T    GE+ ++  +KM+KSLKN+V PD 
Sbjct  568  GMILGTSYRDSRGALVATDKVEKRDGSFFHVET----GEELEQAPAKMSKSLKNVVNPDD  623

Query  774  MYENYGADTFRLYEMSMGPLDESRPWNTRNVVGGMRFLQRLWRNVVDETTGQAHVTEDTP  833
            + E+YGADT+R+YEM MGPLD S +W+   + G+ +FL+R+ R +        ++TE+ +
Sbjct  624  VVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTK-----EITEENS  678

Query  834  DEKTLKLLNNTIAEVTAEMEGMRPNTAIAKLIVLNNHLTGLKAVPRAAVEPLILMLAPIA  893
            +    K+ N+T+  VT +++ M+ NTAIA+L+V+ N       +       ++ ++AP+A
Sbjct  679  GALD-KVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFA  737

Query  894  PHICEEMWSKL-GHAESLSAEPWPVADERYVGHDTVTAVVQIKGKVRAKLEVPVDIDPAD  952
            PH+ EE+W  L + +ES+S  PWP  DE  + ++ V  VVQIKGKV+AKL V+ D+   +
Sbjct  738  PHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREE  797

Query  953  LEKQALAA--VADRLGGKEPRKVIVKAPKIVSIV  984
            L+  ALA   V   ++GK+  KVI  + K+V+IV
Sbjct  798  LQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIV  831


 Score =  137 bits (502),  Expect = 5e-33, Method: Compositional matrix adjust.
 Identities = 75/150 (50%), Positives = 104/150 (70%), Gaps = 12/150 (8%)

Query  25   IENKWQKIWDEQGTFWAANVNGDLKDGKGRNAEGRTAYFAMDMFPYPSGKGLHVGHPLGY  84
            IE KWQ +W ++ TF            K     ++  ++A+DMFPYPSG GLHVGHP GY
Sbjct  9    IEPKWQAFWADNHTF------------KTGTDASKPKFYALDMFPYPSGAGLHVGHPEGY  56

Query  85   LASDVVSRYHRMKGENVLHAMGYDAFGLPAEQYAVQTGQHPRVTTEANIANMSRQLHRMG  144
             A+D++SR+ R +G+NVLH+MG DAFGLPAEQYA++TG++P   T  NIAN  RQ++ +G
Sbjct  57   TATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALG  116

Query  145  LSFDNRRTFATIDPGYVRWTQWIFSRIYDS  174
            +S+D  R   T DP Y +WTQWIF+++Y+ 
Sbjct  117  FSYDWDREVNTTDPNYYKWTQWIFTKLYEK  146

1700) BLLJ_1149 in NC_015067


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  482 bits (1819),  Expect = 4e-137, Method: Compositional matrix adjust.
 Identities = 332/754 (45%), Positives = 477/754 (64%), Gaps = 73/754 (9%)

Query  234  LAYISKSPVNWCPGLGTVLANEEVTAEGKSERGNFPVFQRELRQWSMRITKYGHRLIADL  293
            LAY +  PVNW   LGT +ANEEV ++G SERG +PV ++ +RQW ++IT Y++RL+ DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  294  DGINWPEKVKLMQRNWIGESHGASVHFTVATADGDKDMEIYTTRPDTLFGTTFAVVSPEH  353
            + ++WPE +K MQRNWIG S GA+V F V   D DKD  ++TTRPDTLFG+T+AV++PEH
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKV--KDTDKDFTVFTTRPDTLFGATYAVLAPEH  265

Query  354  HLLENVPAEWPADVPEDWKGGYANPVEAVKAYRLAAEAKTAKDRVNEAGEKTGLFTGLYA  413
             L++ + +              ++  EAV  Y+  A  K+   R + A EKTG+ TG YA
Sbjct  266  ALVDAITT--------------SDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYA  311

Query  414  TNPITGAKLPLFTADYVLMDYGTGAIMAVPGGDQRDYDFAVKFGLPVIYTVTPLPDSGDD  473
             NP+ G  +P+  ADYVL  YGTGAIMAVP+ D+RD +FA +F L +I    P+ ++G+ 
Sbjct  312  INPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDII----PVLEGGN-  366

Query  474  LANYEGKAPFVSHDGIVINSSVEATEAKGDALSLNGLRVDDAIAKVNAWLESAGVGKGTV  533
                   A+F ++DG+ INS             L+GL    AIAK+  WLE+ GVG+  V
Sbjct  367  ----VEEAAF-TEDGLHINSDF-----------LDGLDKASAIAKMVEWLEAEGVGNENV  410

Query  534  SYRLRDWLFSRQRYWGEPFPIVYGEDGTPHLLPDSALPINLPDVPDYEPRTFDPMDAESN  593
            +YRLRDWLFSRQRYWGEP+PI+  EDGT+  +P+S LP+ LP   D  P         + 
Sbjct  411  TYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGT  462

Query  594  PEAPLSRNEDWVKVELDLGDGKKTYYRDTNTMPNWAGSCWYYMRYIDPTDTKHMVEKDEF  653
             E+PL+   DW+ V  + G   +   R+TNTMP+WAGS WYY+RYIDP +T  + + + +
Sbjct  463  GESPLANVTDWLEVTREDGVKGR---RETNTMPQWAGSSWYYLRYIDPHNTEKLADEELL  519

Query  654  DYWMGPNHNKYSGDEGGVDLYIGGVEHAVLHLLYSRFWHKVLFDLGYVDSAEPFHKLFNQ  713
              W+             VD+Y+GG EHAVLHLLY+RFWHKVL+DLG V + EPF+KLFNQ
Sbjct  520  KQWL------------PVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQ  567

Query  714  GMIQAYAYTDDRGQYVPADEVVEGPADASGEPTFTWNGEHANREFGKMGKSLKNIVTPDY  773
            GMI + +Y D RG  V++D V    +      T    GE+ ++  +KM+KSLKN+V PD 
Sbjct  568  GMILGTSYRDSRGALVATDKVEKRDGSFFHVET----GEELEQAPAKMSKSLKNVVNPDD  623

Query  774  MYENYGADTFRLYEMSMGPLDESRPWNTRNVVGGMRFLQRLWRNVVDETTGQAHVTEDTP  833
            + E+YGADT+R+YEM MGPLD S +W+   + G+ +FL+R+ R +        ++TE+ +
Sbjct  624  VVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTK-----EITEENS  678

Query  834  DEKTLKLLNNTIAEVTAEMEGMRPNTAIAKLIVLNNHLTGLKAVPRAAVEPLILMLAPIA  893
            +    K+ N+T+  VT +++ M+ NTAIA+L+V+ N       +       ++ ++AP+A
Sbjct  679  GALD-KVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFA  737

Query  894  PHICEEMWSKL-GHAESLSAEPWPVADERYVGHDTVTAVVQIKGKVRAKLEVPVDIDPAD  952
            PH+ EE+W  L + +ES+S  PWP  DE  + ++ V  VVQIKGKV+AKL V+ D+   +
Sbjct  738  PHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREE  797

Query  953  LEKQALAA--VADRLGGKEPRKVIVKAPKIVSIV  984
            L+  ALA   V   ++GK+  KVI  + K+V+IV
Sbjct  798  LQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIV  831


 Score =  137 bits (502),  Expect = 5e-33, Method: Compositional matrix adjust.
 Identities = 75/150 (50%), Positives = 104/150 (70%), Gaps = 12/150 (8%)

Query  25   IENKWQKIWDEQGTFWAANVNGDLKDGKGRNAEGRTAYFAMDMFPYPSGKGLHVGHPLGY  84
            IE KWQ +W ++ TF            K     ++  ++A+DMFPYPSG GLHVGHP GY
Sbjct  9    IEPKWQAFWADNHTF------------KTGTDASKPKFYALDMFPYPSGAGLHVGHPEGY  56

Query  85   LASDVVSRYHRMKGENVLHAMGYDAFGLPAEQYAVQTGQHPRVTTEANIANMSRQLHRMG  144
             A+D++SR+ R +G+NVLH+MG DAFGLPAEQYA++TG++P   T  NIAN  RQ++ +G
Sbjct  57   TATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALG  116

Query  145  LSFDNRRTFATIDPGYVRWTQWIFSRIYDS  174
            +S+D  R   T DP Y +WTQWIF+++Y+ 
Sbjct  117  FSYDWDREVNTTDPNYYKWTQWIFTKLYEK  146

1701) BIL_08230 in NC_021008


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  482 bits (1818),  Expect = 5e-137, Method: Compositional matrix adjust.
 Identities = 332/754 (45%), Positives = 477/754 (64%), Gaps = 73/754 (9%)

Query  234  LAYISKSPVNWCPGLGTVLANEEVTAEGKSERGNFPVFQRELRQWSMRITKYGHRLIADL  293
            LAY +  PVNW   LGT +ANEEV ++G SERG +PV ++ +RQW ++IT Y++RL+ DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  294  DGINWPEKVKLMQRNWIGESHGASVHFTVATADGDKDMEIYTTRPDTLFGTTFAVVSPEH  353
            + ++WPE +K MQRNWIG S GA+V F V   D DKD  ++TTRPDTLFG+T+AV++PEH
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKV--KDTDKDFTVFTTRPDTLFGATYAVLAPEH  265

Query  354  HLLENVPAEWPADVPEDWKGGYANPVEAVKAYRLAAEAKTAKDRVNEAGEKTGLFTGLYA  413
             L++ + +              ++  EAV  Y+  A  K+   R + A EKTG+ TG YA
Sbjct  266  ALVDAITT--------------SDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYA  311

Query  414  TNPITGAKLPLFTADYVLMDYGTGAIMAVPGGDQRDYDFAVKFGLPVIYTVTPLPDSGDD  473
             NP+ G  +P+  ADYVL  YGTGAIMAVP+ D+RD +FA +F L +I    P+ ++G+ 
Sbjct  312  INPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDII----PVLEGGN-  366

Query  474  LANYEGKAPFVSHDGIVINSSVEATEAKGDALSLNGLRVDDAIAKVNAWLESAGVGKGTV  533
                   A+F ++DG+ INS             L+GL    AIAK+  WLE+ GVG+  V
Sbjct  367  ----VEEAAF-TEDGLHINSDF-----------LDGLDKASAIAKMVEWLEAEGVGNENV  410

Query  534  SYRLRDWLFSRQRYWGEPFPIVYGEDGTPHLLPDSALPINLPDVPDYEPRTFDPMDAESN  593
            +YRLRDWLFSRQRYWGEP+PI+  EDGT+  +P+S LP+ LP   D  P         + 
Sbjct  411  TYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGT  462

Query  594  PEAPLSRNEDWVKVELDLGDGKKTYYRDTNTMPNWAGSCWYYMRYIDPTDTKHMVEKDEF  653
             E+PL+   DW+ V  + G   +   R+TNTMP+WAGS WYY+RYIDP +T  + + + +
Sbjct  463  GESPLANVTDWLEVTREDGVKGR---RETNTMPQWAGSSWYYLRYIDPHNTEKLADEELL  519

Query  654  DYWMGPNHNKYSGDEGGVDLYIGGVEHAVLHLLYSRFWHKVLFDLGYVDSAEPFHKLFNQ  713
              W+             VD+Y+GG EHAVLHLLY+RFWHKVL+DLG V + EPF+KLFNQ
Sbjct  520  KQWL------------PVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQ  567

Query  714  GMIQAYAYTDDRGQYVPADEVVEGPADASGEPTFTWNGEHANREFGKMGKSLKNIVTPDY  773
            GMI + +Y D RG  V++D V    +      T    GE+ ++  +KM+KSLKN+V PD 
Sbjct  568  GMILGTSYRDSRGALVATDKVEKRDGSFFHVET----GEELEQAPAKMSKSLKNVVNPDD  623

Query  774  MYENYGADTFRLYEMSMGPLDESRPWNTRNVVGGMRFLQRLWRNVVDETTGQAHVTEDTP  833
            + E+YGADT+R+YEM MGPLD S +W+   + G+ +FL+R+ R +        ++TE+ +
Sbjct  624  VVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTK-----EITEENS  678

Query  834  DEKTLKLLNNTIAEVTAEMEGMRPNTAIAKLIVLNNHLTGLKAVPRAAVEPLILMLAPIA  893
            +    K+ N+T+  VT +++ M+ NTAIA+L+V+ N       +       ++ ++AP+A
Sbjct  679  GALD-KVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFA  737

Query  894  PHICEEMWSKL-GHAESLSAEPWPVADERYVGHDTVTAVVQIKGKVRAKLEVPVDIDPAD  952
            PH+ EE+W  L + +ES+S  PWP  DE  + ++ V  VVQIKGKV+AKL V+ D+   +
Sbjct  738  PHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREE  797

Query  953  LEKQALAA--VADRLGGKEPRKVIVKAPKIVSIV  984
            L+  ALA   V   ++GK+  KVI  + K+V+IV
Sbjct  798  LQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIV  831


 Score =  136 bits (498),  Expect = 1e-32, Method: Compositional matrix adjust.
 Identities = 75/149 (51%), Positives = 103/149 (70%), Gaps = 12/149 (8%)

Query  25   IENKWQKIWDKQGTFWAANVNGDLKDGKGRNAEGRTAYFAMDMFPYPSGKGLHVGHPLGY  84
            IE KWQ +W  + TF            K     ++  ++A+DMFPYPSG GLHVGHP GY
Sbjct  9    IEPKWQAFWADNHTF------------KTGTDASKPKFYALDMFPYPSGAGLHVGHPEGY  56

Query  85   LASDVVSRYHRMKGENVLHAMGYDAFGLPAEQYAVQTGQHPRVTTEANIANMSRQLHRMG  144
             A+D++SR+ R +G+NVLH+MG DAFGLPAEQYA++TG++P   T  NIAN  RQ++ +G
Sbjct  57   TATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALG  116

Query  145  LSFDNRRTFATIDPGYVRWTQWIFSRIYD  173
            +S+D  R   T DP Y +WTQWIF+++Y+
Sbjct  117  FSYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1702) leuS in NC_013721


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  482 bits (1816),  Expect = 6e-137, Method: Compositional matrix adjust.
 Identities = 336/755 (45%), Positives = 481/755 (64%), Gaps = 74/755 (9%)

Query  239  IAYISKSPVNWCPGLGTVLANEEVTAEGKSERGNFPVFQRNLRQWSMRITAYGHRLVEDL  298
            +AY +  PVNW   LGT +ANEEV ++G SERG +PV ++ +RQW ++ITAY++RL+EDL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  299  NTIDWSEKVKLMQRNWIGESHGASVHFEVPCADGETRDLEVYTTRPDTLFGTTFAVVSVD  358
            + +DW+E +K MQRNWIG S GA+V F V  +D   +D+ V+TTRPDTLFG+T+AV++ +
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD---KDFTVFTTRPDTLFGATYAVLAPE  264

Query  359  HPILEHVPEAWGADVPESWKGGYASLKEGLAEYQAQARAKTAKDRTEDAGAKTGLFTGLY  418
            H++++ +                +   E++A+Y+ QA  K+   RT+ A  KTG+ TG Y
Sbjct  265  HALVDAITT--------------SDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSY  310

Query  419  AINPVNGAKLPLFAADYVLMGYGTGAIMAVPGGDQRDYDFAKAFGLPVIYTVEPLPDSEE  478
            AINPVNG  +P+  ADYVL +YGTGAIMAVP+ D+RD +FAK F L +I    P+ ++ +
Sbjct  311  AINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDII----PVLEGGN  366

Query  479  KLADYEGKAPFVSHDGIVINSAVEHTHKLGDALSINGLRVDEAIKKVTTWLEAAGVGKGR  538
                    A+F ++DG+ INS             ++GL    AI K+  WLEA GVG+  
Sbjct  367  -----VEEAAF-TEDGLHINSDF-----------LDGLDKASAIAKMVEWLEAEGVGNEN  409

Query  539  VSYRLRDWLFSRQRYWGEPFPIVYDEDGVAHLVPDSELPIALPDVPDYQPKTYAPDDANS  598
            V+YRLRDWLFSRQRYWGEP+PI+  EDG +  VP+SELP+ LP   D +P        ++
Sbjct  410  VTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SG  461

Query  599  EPEAPLSRNEDWVKVQLDLGDGVKTYYRDTNTMPNWAGSCWYYMRYLDPNDAEHMVDSDE  658
              E+PL+   DW+ V  +  DGVK   R+TNTMP+WAGS WYY+RY+DP+++E + D + 
Sbjct  462  TGESPLANVTDWLEVTRE--DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEEL  518

Query  659  YDYWMGTNRPGKEHVSGGVDLYVGGVEHAVLHLLYSRFWHKALYDLGYVDSAEPFHRLFN  718
               W+             VD+YVGG EHAVLHLLY+RFWHK LYDLG V + EPF++LFN
Sbjct  519  LKQWL------------PVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFN  566

Query  719  QGMIQAYAYTDERGQYVPADEVEEGASNSAGEPTFTWHGESVNREFGKMGKSLKNIVTPD  778
            QGMI + +Y D RG  V++D VE   ++     T    GE +++  +KM+KSLKN+V PD
Sbjct  567  QGMILGTSYRDSRGALVATDKVEKRDGSFFHVET----GEELEQAPAKMSKSLKNVVNPD  622

Query  779  YMYENYGADTFRLYEMSMGPLSESRPWNTRNVVGGMRFLQRLWRNVVNEETGACVVTDDA  838
             + E+YGADT+R+YEM MGPL  S +W+   + G+ +FL+R+ R +   E        +A
Sbjct  623  DVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITE--ENSGA  680

Query  839  LDEKTLKILNNTIAEVTVEMEAMRPNTAIAKLIVLNNHLTSLPHVPRAAVEPLVLMLAPI  898
            LD    K+ N+T+  VT +++ M+ NTAIA+L+V+ N       +       +V ++AP+
Sbjct  681  LD----KVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPF  736

Query  899  APHICEEMWSKL-GHAKSIAHADWPVADSRYVGEDTVTAVVQIKGKVRAKLEVDPNIDAS  957
            APH+ EE+W  L + + SI+   WP  D   + E+ V  VVQIKGKV+AKL V  ++   
Sbjct  737  APHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSRE  796

Query  958  ELEKLAL--EAVADRLGGKAPRKVIVKAPKIVSIV  990
            EL+ +AL  E V   ++GK   KVI  + K+V+IV
Sbjct  797  ELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIV  831


 Score =  138 bits (506),  Expect = 2e-33, Method: Compositional matrix adjust.
 Identities = 80/149 (54%), Positives = 107/149 (72%), Gaps = 12/149 (8%)

Query  32   IEQRWQKTWDEQGTFWAANVKGDLKDGEGKLADGRPSFFAMDMFPYPSGKGLHVGHPLGY  91
            IE +WQ  W ++ TF         K G +    ++P F+A+DMFPYPSG GLHVGHP GY
Sbjct  9    IEPKWQAFWADNHTF---------KTGTD---ASKPKFYALDMFPYPSGAGLHVGHPEGY  56

Query  92   LATDVVSRYHRMKGENVLHAMGYDAFGLPAEQYAVQTGQHPRITTEANIANMRRQLHRMG  151
             ATD++SR+ R +G+NVLH+MG DAFGLPAEQYA++TG++P   T  NIAN +RQ++ +G
Sbjct  57   TATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALG  116

Query  152  LSFDDRRSFATIDTNYVRWTQWIFSKLYD  180
            +S+D  R   T D NY +WTQWIF+KLY+
Sbjct  117  FSYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1703) leuS in NC_010612


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  481 bits (1813),  Expect = 1e-136, Method: Compositional matrix adjust.
 Identities = 338/742 (46%), Positives = 505/742 (69%), Gaps = 56/742 (7%)

Query  237  DHRLVYRADSMVNWCPGLGTVLANEEVTSDGRSDRGNFPVFRKRLRQWMMRITAYSdrll  296
            +  L Y A+  VNW   LGT +ANEEV +DG S+RG +PV RK +RQWM++ITAY++RLL
Sbjct  145  EKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLL  204

Query  297  ddldvldwpdQVKTMQRNWIGRSTGASALFTATRSNGETVGLEVFTTRPDTLFGATYLVL  356
            +DL+ +DWP+ +K MQRNWIG+STGA+  F    ++ +   + VFTTRPDTLFGATY VL
Sbjct  205  EDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKD---FTVFTTRPDTLFGATYAVL  261

Query  357  APEHDLVDDLVGAGWPAGVDPLWTGGGatpaeavaayrraiaaKSDLERQE-SKEKTGVF  415
            APEH LVD +  ++ + +V                  +R  + KSDL R + +KEKTGV 
Sbjct  262  APEHALVDAITTSDQAEAVADY---------------KRQASLKSDLARTDLAKEKTGVW  306

Query  416  LGSHAINPATGQPVPIFIADYVLAGYGTGAIMAVPGHDQRDWDFARALGLPVVEVIAGGD  475
             GS AINP  G+ +P+ IADYVLA+YGTGAIMAVP+HD+RDW+FA+ + L ++ V+ GG+
Sbjct  307  TGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGN  366

Query  476  ISQAAYTGDGVLVNSGFLDGMSVGEAKQAITARLESDGHGQARIEFKLRDWLFARQRYWG  535
            + +AA+T DG+ +NS+FLDG+  + A   +  +LE++G G+  + ++LRDWLF+RQRYWG
Sbjct  367  VEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWG  426

Query  536  EPFPIVYDADGRPHALDESALPVELPDVPDYSPVLFDPDDANSEPSPPLGKATEWVHVEL  595
            EP+PI+   DG + A+ ES LP+ LP   D  P        ++   +PL++ T+W++V  
Sbjct  427  EPIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTDWLEVTR  478

Query  596  DLGDGLKPYSRDTNVMPQWAGSSWYELRYTDPHNADRFCAKENETYWMGPRPAEHGPDDP  655
            +  DG+K   R+TN MPQWAGSSWY LRY DPHN++++   E    W+            
Sbjct  479  E--DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWL------------  523

Query  656  GGVDLYVGGAEHAVLHLLYARFWHKVLYDLGHVSSREPYRKLINQGYIQAFAYTDARGSY  715
              VD+YVGGAEHAVLHLLYARFWHKVLYDLG V+++EP++KL+NQG I + +Y D+RG+ 
Sbjct  524  -PVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGAL  582

Query  716  VPAEEVIERDGGFVYPGADGEIEVFQEFGKIGKSLKNSISPDEICDDYGADTLRVYEMSM  775
            V+++ V  RDG+F    ++ E+E  Q  +K++KSLKN ++PD++ ++YGADTLRVYEM M
Sbjct  583  VATDKVEKRDGSFFHVETGEELE--QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFM  640

Query  776  GPIEASRPWATKDVIGAYRFLQRVWRLVIDENTGEILVADTPAELDTDTLRALHRAIAGV  835
            GP++AS +W+  ++ G+ +FL+RV RL+   +  E    + ++ LD    +  + ++ +V
Sbjct  641  GPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITE----ENSGALD----KVYNETVKAV  692

Query  836  AEDYAALRNNTAVAKLIEYTNFLTKRHRDAVPRAAIEPLVLMVAPLAPHLAEELWQRLGH  895
            +E+   ++ NTA+A+L+ + N   K ++  +       +V ++AP+APHL+EELWQ L  
Sbjct  693  TEQVDQMKFNTAIAQLMVFVNAANKEDK--LFSDYAKGFVQLIAPFAPHLGEELWQALTA  750

Query  896  TT-SLAHGPFPAADPAYLIDDTVEYPVQVNGKVRGRvvvaadadddavkaaaladekvQA  954
            +  S++  P P+ D + L+++ VE  VQ++GKV++++VVA D   + ++  ALA+EKVQA
Sbjct  751  SGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQA  810

Query  955  FLAGASPRKVIVVAGRLVNLVV  976
             +AG    KVI V+ +LVN+V+
Sbjct  811  EIAGKDIIKVIAVPNKLVNIVI  832


 Score =  132 bits (486),  Expect = 8e-32, Method: Compositional matrix adjust.
 Identities = 73/150 (49%), Positives = 103/150 (69%), Gaps = 11/150 (7%)

Query  41   AGVERTWQQNWARLGTFNVPNPVGSLAPSDGSPVPEDKLFVQDMFPYPSGEGLHVGHPLG  100
            +++E  WQ  WA   TF+            G+  +  K++  DMFPYPSG GLHVGHP G
Sbjct  7    TAIEPKWQAFWADNHTFKT-----------GTDASKPKFYALDMFPYPSGAGLHVGHPEG  55

Query  101  YIATDVFARYHRMKGRNVLHALGFDAFGLPAEQYAVQTGTHPRTRTEANVVNFRRQLGRL  160
            Y ATD+++R+ R +G+NVLH++G DAFGLPAEQYA++TG +P   T  N+ NF+RQ+  L
Sbjct  56   YTATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINAL  115

Query  161  GLGHDSRRSFSTTDVEFYKWTQWIFLQIYN  190
            G++ D  R  +TTD ++YKWTQWIF ++Y+
Sbjct  116  GFSYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1704) leuS in NC_017999


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  481 bits (1813),  Expect = 1e-136, Method: Compositional matrix adjust.
 Identities = 335/754 (45%), Positives = 478/754 (64%), Gaps = 73/754 (9%)

Query  239  LAYISKSPVNWCPGLGTVLANEEVTAEGKSERGNFPVFQRELRQWSMRITKYGHRLIGDL  298
            LAY +  PVNW   LGT +ANEEV ++G SERG +PV ++ +RQW ++IT Y++RL+ DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  299  DGIDWPEKVKLMQRNWIGESHGASVHFTVATADGSKDMEIYTTRPDTLFGTTFAVVSPEH  358
            + +DWPE +K MQRNWIG S GA+V F V  +D  KD  ++TTRPDTLFG+T+AV++PEH
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD--KDFTVFTTRPDTLFGATYAVLAPEH  265

Query  359  HLLENVPAEWPADVPEDWKGGYATPVEAVKAYRLAAEAKTAKDRVDEGGEKTGLFTGLYA  418
             L++ + +              +   EAV  Y+  A  K+   R D + EKTG+ TG YA
Sbjct  266  ALVDAITT--------------SDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYA  311

Query  419  TNPITGAKLPLFTADYVLMDYGTGAIMAVPGGDQRDYDFAVKFGLPVIYTVKPLPESGDD  478
             NP+ G  +P+  ADYVL  YGTGAIMAVP+ D+RD +FA +F L +I    P+ E+G+ 
Sbjct  312  INPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDII----PVLEGGN-  366

Query  479  LANYEGKAPFVSHDGIVINSSVEATAAKGDALSLNGLRVDDAIAKVNAWLESAGVGKGTV  538
                   A+F ++DG+ INS             L+GL    AIAK+  WLE+ GVG+  V
Sbjct  367  ----VEEAAF-TEDGLHINSDF-----------LDGLDKASAIAKMVEWLEAEGVGNENV  410

Query  539  SYRLRDWLFSRQRYWGEPFPIVYGEDGTPHLLPDSALPISLPDVPDYEPRTFDPMDAESN  598
            +YRLRDWLFSRQRYWGEP+PI+  EDGT+  +P+S LP+ LP   D  P         + 
Sbjct  411  TYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGT  462

Query  599  PEAPLSRNEDWVKVELDLGDGKKTYYRDTNTMPNWAGSCWYYMRYIDPSDTEHMVEKDEF  658
             E+PL+   DW+ V  + G   +   R+TNTMP+WAGS WYY+RYIDP +TE + + + +
Sbjct  463  GESPLANVTDWLEVTREDGVKGR---RETNTMPQWAGSSWYYLRYIDPHNTEKLADEELL  519

Query  659  DYWMGPNHNKYSGDEGGVDLYIGGVEHAVLHLLYSRFWHKVLFDLGYVDSAEPFHKLFNQ  718
              W+             VD+Y+GG EHAVLHLLY+RFWHKVL+DLG V + EPF+KLFNQ
Sbjct  520  KQWL------------PVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQ  567

Query  719  GMIQAYAYTDDRGQYVPADEVVEGPAGADGEPTFTWNGEHANREFGKMGKSLKNIVTPDY  778
            GMI + +Y D RG  V++D  VE   G+  +      GE+ ++  +KM+KSLKN+V PD 
Sbjct  568  GMILGTSYRDSRGALVATDK-VEKRDGSFFHVE---TGEELEQAPAKMSKSLKNVVNPDD  623

Query  779  MYENYGADTFRLYEMSMGPLDESRPWNTRNVVGGMRFLQRLWRNVVDETSGEVHVTEDTP  838
            + E+YGADT+R+YEM MGPLD S +W+   + G+ +FL+R+ R +        ++TE+ +
Sbjct  624  VVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTK-----EITEENS  678

Query  839  DVKTLKLLNNTIAEVTVEMEGMRPNTAIAKLIVLNNHLTSLPAVPRAAVEPLILMLAPIA  898
            +    K+ N+T+  VT +++ M+ NTAIA+L+V+ N       +       ++ ++AP+A
Sbjct  679  GALD-KVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFA  737

Query  899  PHICEEMWSKL-GHDESLSAEPWPVADEKYVGHDTVTAVVQIKGKVRAKLEVPVDIDPAD  957
            PH+ EE+W  L + +ES+S  PWP  DE  + ++ V  VVQIKGKV+AKL V+ D+   +
Sbjct  738  PHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREE  797

Query  958  LEKQAL--EAVADRLGGKTPHKVIVKAPKIVSIV  989
            L+  AL  E V   ++GK   KVI  + K+V+IV
Sbjct  798  LQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIV  831


 Score =  137 bits (504),  Expect = 3e-33, Method: Compositional matrix adjust.
 Identities = 77/150 (52%), Positives = 105/150 (70%), Gaps = 12/150 (8%)

Query  30   IEGKWQKIWDDKGTFWAANVNGDLKDGKGRNADGRPAYFAMDMFPYPSGKGLHVGHPLGY  89
            IE KWQ +W D+ TF            K     ++P ++A+DMFPYPSG GLHVGHP GY
Sbjct  9    IEPKWQAFWADNHTF------------KTGTDASKPKFYALDMFPYPSGAGLHVGHPEGY  56

Query  90   LASDVVSRYHRMKGENVLHAMGYDAFGLPAEQYAVQTGQHPRVTTLANIANMSRQLHRMG  149
             A+D++SR+ R +G+NVLH+MG DAFGLPAEQYA++TG++P   T  NIAN  RQ++ +G
Sbjct  57   TATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALG  116

Query  150  LSFDDRRSFATIDPGYVRWTQWIFSRIYDS  179
            +S+D  R   T DP Y +WTQWIF+++Y+ 
Sbjct  117  FSYDWDREVNTTDPNYYKWTQWIFTKLYEK  146

1705) leuS in NC_014638


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  481 bits (1815),  Expect = 7e-137, Method: Compositional matrix adjust.
 Identities = 335/754 (45%), Positives = 479/754 (64%), Gaps = 73/754 (9%)

Query  239  LAYISKSPVNWCPGLGTVLANEEVTAEGKSERGNFPVFQRELRQWSMRITKYGHRLIEDL  298
            LAY +  PVNW   LGT +ANEEV ++G SERG +PV ++ +RQW ++IT Y++RL+EDL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  299  DGIDWPEKVKLMQRNWIGESHGASVHFTVDTADGSKDMEIYTTRPDTLFGTTFAVVSPEH  358
            + +DWPE +K MQRNWIG S GA+V F V  +D  KD  ++TTRPDTLFG+T+AV++PEH
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD--KDFTVFTTRPDTLFGATYAVLAPEH  265

Query  359  HLLENVPAEWPADVPEDWKGGYATPVEAVKAYRLAAEAKTAKDRVDEGGEKTGLFTGLYA  418
             L++ + +              +   EAV  Y+  A  K+   R D + EKTG+ TG YA
Sbjct  266  ALVDAITT--------------SDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYA  311

Query  419  TNPITGAKLPLFTADYVLMDYGTGAIMAVPGGDQRDYDFAVKFALPVIYTVKPLPESGDD  478
             NP+ G  +P+  ADYVL  YGTGAIMAVP+ D+RD +FA +F L +I    P+ E+G+ 
Sbjct  312  INPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDII----PVLEGGN-  366

Query  479  LANYEGKAPFVSHDGIVINSSVEATAAKGDALSLNGLRVDDAIAKVNAWLESAGVGKGTV  538
                   A+F ++DG+ INS             L+GL    AIAK+  WLE+ GVG+  V
Sbjct  367  ----VEEAAF-TEDGLHINSDF-----------LDGLDKASAIAKMVEWLEAEGVGNENV  410

Query  539  SYRLRDWLFSRQRYWGEPFPIVYGEDGAPHLLPDSALPINLPDVPDYEPRTFDPMDAESN  598
            +YRLRDWLFSRQRYWGEP+PI+  EDG++  +P+S LP+ LP   D  P         + 
Sbjct  411  TYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGT  462

Query  599  PEAPLSRNEDWVKVELDLGDGKKTYYRDTNTMPNWAGSCWYYMRYIDPSDTEHMVEKDEF  658
             E+PL+   DW+ V  + G   +   R+TNTMP+WAGS WYY+RYIDP +TE + + + +
Sbjct  463  GESPLANVTDWLEVTREDGVKGR---RETNTMPQWAGSSWYYLRYIDPHNTEKLADEELL  519

Query  659  DYWMGPNHNKYSGDEGGVDLYIGGVEHAVLHLLYSRFWHKVLFDLGYVDSAEPFHKLFNQ  718
              W+             VD+Y+GG EHAVLHLLY+RFWHKVL+DLG V + EPF+KLFNQ
Sbjct  520  KQWL------------PVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQ  567

Query  719  GMIQAYAYTDDRGQYVPADEVVEGPAGADGEPTFTWNGEHANREFGKMGKSLKNIVTPDY  778
            GMI + +Y D RG  V++D  VE   G+  +      GE+ ++  +KM+KSLKN+V PD 
Sbjct  568  GMILGTSYRDSRGALVATDK-VEKRDGSFFHVE---TGEELEQAPAKMSKSLKNVVNPDD  623

Query  779  MYENYGADTFRLYEMSMGPLDESRPWNTRNVVGGMRFLQRLWRNVVDETSGEAHVTEDTP  838
            + E+YGADT+R+YEM MGPLD S +W+   + G+ +FL+R+ R +        ++TE+ +
Sbjct  624  VVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTK-----EITEENS  678

Query  839  DVKTLKLLNNTIAEVTVEMEGMRPNTAIAKLIVLNNHLTSLPAVPRAAVEPLILMLAPIA  898
            +    K+ N+T+  VT +++ M+ NTAIA+L+V+ N       +       ++ ++AP+A
Sbjct  679  GALD-KVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFA  737

Query  899  PHICEEMWSKL-GHDESLSAEPWPVADEKYVGHDTVTAVVQIKGKVRAKLEVPVDIDPAD  957
            PH+ EE+W  L + +ES+S  PWP  DE  + ++ V  VVQIKGKV+AKL V+ D+   +
Sbjct  738  PHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREE  797

Query  958  LEKQAL--EAVADRLGGKTPHKVIVKAPKIVSIV  989
            L+  AL  E V   ++GK   KVI  + K+V+IV
Sbjct  798  LQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIV  831


 Score =  137 bits (504),  Expect = 3e-33, Method: Compositional matrix adjust.
 Identities = 77/150 (52%), Positives = 105/150 (70%), Gaps = 12/150 (8%)

Query  30   IEGKWQKIWDDKGTFWAANVNGDLKDGKGRNADGRPAYFAMDMFPYPSGKGLHVGHPLGY  89
            IE KWQ +W D+ TF            K     ++P ++A+DMFPYPSG GLHVGHP GY
Sbjct  9    IEPKWQAFWADNHTF------------KTGTDASKPKFYALDMFPYPSGAGLHVGHPEGY  56

Query  90   LASDVVSRYHRMKGENVLHAMGYDAFGLPAEQYAVQTGQHPRVTTLANIANMSRQLHRMG  149
             A+D++SR+ R +G+NVLH+MG DAFGLPAEQYA++TG++P   T  NIAN  RQ++ +G
Sbjct  57   TATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALG  116

Query  150  LSFDDRRSFATIDPGYVRWTQWIFSRIYDS  179
            +S+D  R   T DP Y +WTQWIF+++Y+ 
Sbjct  117  FSYDWDREVNTTDPNYYKWTQWIFTKLYEK  146

1706) leuS in NC_017218


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  481 bits (1815),  Expect = 7e-137, Method: Compositional matrix adjust.
 Identities = 330/754 (44%), Positives = 476/754 (64%), Gaps = 73/754 (9%)

Query  234  LAYISKSPVNWCPGLGTVLANEEVTAEGKSERGNFPVFQRELRQWSMRITKYGHRLIEDL  293
            LAY +  PVNW   LGT +ANEEV ++G SERG +PV ++ +RQW ++IT Y++RL+EDL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  294  DGINWPEKVKLMQRNWIGESHGASVHFTVATADGSKDMEIYTTRPDTLFGTTFAVVSPEH  353
            + ++WPE +K MQRNWIG S GA+V F V  +D  KD  ++TTRPDTLFG+T+AV++PEH
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD--KDFTVFTTRPDTLFGATYAVLAPEH  265

Query  354  HLLENVPAEWPADVPEDWKGGYANPVEAVKAYRLAAEAKTAKDRVDEAGEKTGLFTGLYA  413
             L++ + +              ++  EAV  Y+  A  K+   R D A EKTG+ TG YA
Sbjct  266  ALVDAITT--------------SDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYA  311

Query  414  TNPITGAKLPLFTADYVLMDYGTGAIMAVPGGDQRDYDFAVKFGLPVIYTVKPLPESGDD  473
             NP+ G  +P+  ADYVL  YGTGAIMAVP+ D+RD +FA +F L +I    P+ E+G+ 
Sbjct  312  INPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDII----PVLEGGN-  366

Query  474  LANYEGKAPFVSHDGIVINSFVEATAAKGDALSLDGLRVDDAIAKVNAWLESAGIGKGTV  533
                   A+F  ++  + + F            LDGL    AIAK+  WLE+ G+G+  V
Sbjct  367  ----VEEAAFTEDGLHINSDF------------LDGLDKASAIAKMVEWLEAEGVGNENV  410

Query  534  SYRLRDWLFSRQRYWGEPFPIVYGEDGTPHLLPDSALPINLPDVPDYEPRTFDPMDAESD  593
            +YRLRDWLFSRQRYWGEP+PI+  EDGT+  +P+S LP+ LP   D  P         + 
Sbjct  411  TYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGT  462

Query  594  PEAPLSRNEDWVKVELDLGDGVKTYYRDTNTMPNWAGSCWYYMRYIDPTDTKHMVEKDEF  653
             E+PL+   DW+ V  +  DGVK   R+TNTMP+WAGS WYY+RYIDP +T  + + + +
Sbjct  463  GESPLANVTDWLEVTRE--DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELL  519

Query  654  DYWMGPNHNKYSGDEGGVDLYIGGVEHAVLHLLYSRFWHKVLFDLGYVDSAEPFHKLFNQ  713
              W+             VD+Y+GG EHAVLHLLY+RFWHKVL+DLG V + EPF+KLFNQ
Sbjct  520  KQWL------------PVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQ  567

Query  714  GMIQAYAYTDDRGQYVPADEVVEGEPDASGEPTFTWNGEHANREFGKMGKSLKNIVTPDY  773
            GMI + +Y D RG  V++D V   +       T    GE+ ++  +KM+KSLKN+V PD 
Sbjct  568  GMILGTSYRDSRGALVATDKVEKRDGSFFHVET----GEELEQAPAKMSKSLKNVVNPDD  623

Query  774  MYENYGADTFRLYEMSMGPLDESRPWNTRNVVGGMRFLQRLWRNVVNETTGEVHVSEETP  833
            + E+YGADT+R+YEM MGPLD S +W+   + G+ +FL+R+ R +        +++EE +
Sbjct  624  VVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTK-----EITEENS  678

Query  834  DEKTLKLLNNTIAEVTAEMEGMRPNTAIAKLIVLNNHLTGLKAVPRAAVEPLILMLAPIA  893
            +    K+ N+T+  VT +++ M+ NTAIA+L+V+ N       +       ++ ++AP+A
Sbjct  679  GALD-KVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFA  737

Query  894  PHICEEMWNKL-GHADSLSAEPWPVADERYVGHDTVTAVVQIKGKVRAKLEVPVDIDPAD  952
            PH+ EE+W+ L + ++S+S  PWP  DE  + ++ V  VVQIKGKV+AKL V+ D+   +
Sbjct  738  PHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREE  797

Query  953  LEK--QARAAVADRLGGKEPRKVIVKAPKIVSIV  984
            L+    A   V   ++GK+  KVI  + K+V+IV
Sbjct  798  LQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIV  831


 Score =  137 bits (502),  Expect = 5e-33, Method: Compositional matrix adjust.
 Identities = 75/149 (51%), Positives = 104/149 (70%), Gaps = 12/149 (8%)

Query  25   IENKWQKIWDEKGTFWAANVNGDLKDGKGRNAEGRTAYFAMDMFPYPSGKGLHVGHPLGY  84
            IE KWQ +W ++ TF            K     ++  ++A+DMFPYPSG GLHVGHP GY
Sbjct  9    IEPKWQAFWADNHTF------------KTGTDASKPKFYALDMFPYPSGAGLHVGHPEGY  56

Query  85   LASDVVSRYHRMKGENVLHAMGYDAFGLPAEQYAVQTGQHPRVTTEANIANMSRQLHRMG  144
             A+D++SR+ R +G+NVLH+MG DAFGLPAEQYA++TG++P   T  NIAN  RQ++ +G
Sbjct  57   TATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALG  116

Query  145  LSFDNRRTFATIDPGYVRWTQWIFSRIYD  173
            +S+D  R   T DP Y +WTQWIF+++Y+
Sbjct  117  FSYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1707) leuS in NC_020517


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  481 bits (1815),  Expect = 7e-137, Method: Compositional matrix adjust.
 Identities = 330/754 (44%), Positives = 476/754 (64%), Gaps = 73/754 (9%)

Query  234  LAYISKSPVNWCPGLGTVLANEEVTAEGKSERGNFPVFQRELRQWSMRITKYGHRLIEDL  293
            LAY +  PVNW   LGT +ANEEV ++G SERG +PV ++ +RQW ++IT Y++RL+EDL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  294  DGINWPEKVKLMQRNWIGESHGASVHFTVATADGSKDMEIYTTRPDTLFGTTFAVVSPEH  353
            + ++WPE +K MQRNWIG S GA+V F V  +D  KD  ++TTRPDTLFG+T+AV++PEH
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD--KDFTVFTTRPDTLFGATYAVLAPEH  265

Query  354  HLLENVPAEWPADVPEDWKGGYANPVEAVKAYRLAAEAKTAKDRVDEAGEKTGLFTGLYA  413
             L++ + +              ++  EAV  Y+  A  K+   R D A EKTG+ TG YA
Sbjct  266  ALVDAITT--------------SDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYA  311

Query  414  TNPITGAKLPLFTADYVLMDYGTGAIMAVPGGDQRDYDFAVKFGLPVIYTVKPLPESGDD  473
             NP+ G  +P+  ADYVL  YGTGAIMAVP+ D+RD +FA +F L +I    P+ E+G+ 
Sbjct  312  INPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDII----PVLEGGN-  366

Query  474  LANYEGKAPFVSHDGIVINSFVEATAAKGDALSLDGLRVDDAIAKVNAWLESAGIGKGTV  533
                   A+F  ++  + + F            LDGL    AIAK+  WLE+ G+G+  V
Sbjct  367  ----VEEAAFTEDGLHINSDF------------LDGLDKASAIAKMVEWLEAEGVGNENV  410

Query  534  SYRLRDWLFSRQRYWGEPFPIVYGEDGTPHLLPDSALPINLPDVPDYEPRTFDPMDAESD  593
            +YRLRDWLFSRQRYWGEP+PI+  EDGT+  +P+S LP+ LP   D  P         + 
Sbjct  411  TYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGT  462

Query  594  PEAPLSRNEDWVKVELDLGDGVKTYYRDTNTMPNWAGSCWYYMRYIDPTDTKHMVEKDEF  653
             E+PL+   DW+ V  +  DGVK   R+TNTMP+WAGS WYY+RYIDP +T  + + + +
Sbjct  463  GESPLANVTDWLEVTRE--DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELL  519

Query  654  DYWMGPNHNKYSGDEGGVDLYIGGVEHAVLHLLYSRFWHKVLFDLGYVDSAEPFHKLFNQ  713
              W+             VD+Y+GG EHAVLHLLY+RFWHKVL+DLG V + EPF+KLFNQ
Sbjct  520  KQWL------------PVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQ  567

Query  714  GMIQAYAYTDDRGQYVPADEVVEGEPDASGEPTFTWNGEHANREFGKMGKSLKNIVTPDY  773
            GMI + +Y D RG  V++D V   +       T    GE+ ++  +KM+KSLKN+V PD 
Sbjct  568  GMILGTSYRDSRGALVATDKVEKRDGSFFHVET----GEELEQAPAKMSKSLKNVVNPDD  623

Query  774  MYENYGADTFRLYEMSMGPLDESRPWNTRNVVGGMRFLQRLWRNVVNETTGEVHVSEETP  833
            + E+YGADT+R+YEM MGPLD S +W+   + G+ +FL+R+ R +        +++EE +
Sbjct  624  VVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTK-----EITEENS  678

Query  834  DEKTLKLLNNTIAEVTAEMEGMRPNTAIAKLIVLNNHLTGLKAVPRAAVEPLILMLAPIA  893
            +    K+ N+T+  VT +++ M+ NTAIA+L+V+ N       +       ++ ++AP+A
Sbjct  679  GALD-KVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFA  737

Query  894  PHICEEMWNKL-GHADSLSAEPWPVADERYVGHDTVTAVVQIKGKVRAKLEVPVDIDPAD  952
            PH+ EE+W+ L + ++S+S  PWP  DE  + ++ V  VVQIKGKV+AKL V+ D+   +
Sbjct  738  PHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREE  797

Query  953  LEK--QARAAVADRLGGKEPRKVIVKAPKIVSIV  984
            L+    A   V   ++GK+  KVI  + K+V+IV
Sbjct  798  LQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIV  831


 Score =  137 bits (502),  Expect = 5e-33, Method: Compositional matrix adjust.
 Identities = 75/149 (51%), Positives = 104/149 (70%), Gaps = 12/149 (8%)

Query  25   IENKWQKIWDEKGTFWAANVNGDLKDGKGRNAEGRTAYFAMDMFPYPSGKGLHVGHPLGY  84
            IE KWQ +W ++ TF            K     ++  ++A+DMFPYPSG GLHVGHP GY
Sbjct  9    IEPKWQAFWADNHTF------------KTGTDASKPKFYALDMFPYPSGAGLHVGHPEGY  56

Query  85   LASDVVSRYHRMKGENVLHAMGYDAFGLPAEQYAVQTGQHPRVTTEANIANMSRQLHRMG  144
             A+D++SR+ R +G+NVLH+MG DAFGLPAEQYA++TG++P   T  NIAN  RQ++ +G
Sbjct  57   TATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALG  116

Query  145  LSFDNRRTFATIDPGYVRWTQWIFSRIYD  173
            +S+D  R   T DP Y +WTQWIF+++Y+
Sbjct  117  FSYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1708) leuS in NC_014616


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  481 bits (1814),  Expect = 8e-137, Method: Compositional matrix adjust.
 Identities = 335/754 (45%), Positives = 479/754 (64%), Gaps = 73/754 (9%)

Query  239  LAYISKSPVNWCPGLGTVLANEEVTAEGKSERGNFPVFQRELRQWSMRITKYGHRLIEDL  298
            LAY +  PVNW   LGT +ANEEV ++G SERG +PV ++ +RQW ++IT Y++RL+EDL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  299  DGIDWPEKVKLMQRNWIGESHGASVHFTVATADGSKDMEIYTTRPDTLFGTTFAVVSPEH  358
            + +DWPE +K MQRNWIG S GA+V F V  +D  KD  ++TTRPDTLFG+T+AV++PEH
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD--KDFTVFTTRPDTLFGATYAVLAPEH  265

Query  359  HLLENVPAEWPADVPEDWKGGYATPVEAVKAYRLAAEAKTAKDRVDEGGEKTGLFTGLYA  418
             L++ + +              +   EAV  Y+  A  K+   R D + EKTG+ TG YA
Sbjct  266  ALVDAITT--------------SDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYA  311

Query  419  TNPITGAKLPLFTADYVLMDYGTGAIMAVPGGDQRDYDFAVKFGLPVIYTVKPLPESGDD  478
             NP+ G  +P+  ADYVL  YGTGAIMAVP+ D+RD +FA +F L +I    P+ E+G+ 
Sbjct  312  INPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDII----PVLEGGN-  366

Query  479  LANYEGKAPFVSHDGIVINSSVEATAAKGDALSLNGLRVDDAIAKVNAWLESAGVGKGTV  538
                   A+F ++DG+ INS             L+GL    AIAK+  WLE+ GVG+  V
Sbjct  367  ----VEEAAF-TEDGLHINSDF-----------LDGLDKASAIAKMVEWLEAEGVGNENV  410

Query  539  SYRLRDWLFSRQRYWGEPFPIVYGEDGAPHLLPDSALPINLPDVPDYEPRTFDPMDAESN  598
            +YRLRDWLFSRQRYWGEP+PI+  EDG++  +P+S LP+ LP   D  P         + 
Sbjct  411  TYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGT  462

Query  599  PEAPLSRNEDWVKVELDLGDGKKTYYRDTNTMPNWAGSCWYYMRYIDPSDTEHMVEKDEF  658
             E+PL+   DW+ V  + G   +   R+TNTMP+WAGS WYY+RYIDP +TE + + + +
Sbjct  463  GESPLANVTDWLEVTREDGVKGR---RETNTMPQWAGSSWYYLRYIDPHNTEKLADEELL  519

Query  659  DYWMGPNHNKYSGDEGGVDLYIGGVEHAVLHLLYSRFWHKVLFDLGYVDSAEPFHKLFNQ  718
              W+             VD+Y+GG EHAVLHLLY+RFWHKVL+DLG V + EPF+KLFNQ
Sbjct  520  KQWL------------PVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQ  567

Query  719  GMIQAYAYTDDRGQYVPADEVVEGPAGADGEPTFTWNGEHANREFGKMGKSLKNIVTPDY  778
            GMI + +Y D RG  V++D  VE   G+  +      GE+ ++  +KM+KSLKN+V PD 
Sbjct  568  GMILGTSYRDSRGALVATDK-VEKRDGSFFHVE---TGEELEQAPAKMSKSLKNVVNPDD  623

Query  779  MYENYGADTFRLYEMSMGPLDESRPWNTRNVVGGMRFLQRLWRNVVDETSGEAHVTEDTP  838
            + E+YGADT+R+YEM MGPLD S +W+   + G+ +FL+R+ R +        ++TE+ +
Sbjct  624  VVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTK-----EITEENS  678

Query  839  DVKTLKLLNNTIAEVTVEMEGMRPNTAIAKLIVLNNHLTSLPAVPRAAVEPLILMLAPIA  898
            +    K+ N+T+  VT +++ M+ NTAIA+L+V+ N       +       ++ ++AP+A
Sbjct  679  GALD-KVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFA  737

Query  899  PHICEEMWSKL-GHDESLSAEPWPVADEKYVGHDTVTAVVQIKGKVRAKLEVPVDIDPAD  957
            PH+ EE+W  L + +ES+S  PWP  DE  + ++ V  VVQIKGKV+AKL V+ D+   +
Sbjct  738  PHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREE  797

Query  958  LEKQAL--EAVADRLGGKTPHKVIVKAPKIVSIV  989
            L+  AL  E V   ++GK   KVI  + K+V+IV
Sbjct  798  LQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIV  831


 Score =  136 bits (499),  Expect = 8e-33, Method: Compositional matrix adjust.
 Identities = 77/150 (52%), Positives = 104/150 (70%), Gaps = 12/150 (8%)

Query  30   IEGKWQKIWDDKGTFWAANVNGDLKDGKGRNADGRPAYFAMDMFPYPSGKGLHVGHPLGY  89
            IE KWQ +W D+ TF            K     ++P ++A+DMFPYPSG GLHVGHP GY
Sbjct  9    IEPKWQAFWADNHTF------------KTGTDASKPKFYALDMFPYPSGAGLHVGHPEGY  56

Query  90   LASDVASRYHRMKGENVLHAMGYDAFGLPAEQYAVQTGQHPRVTTLANIANMSRQLHRMG  149
             A+D+ SR+ R +G+NVLH+MG DAFGLPAEQYA++TG++P   T  NIAN  RQ++ +G
Sbjct  57   TATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALG  116

Query  150  LSFDDRRSFATIDPGYVRWTQWIFSRIYDS  179
            +S+D  R   T DP Y +WTQWIF+++Y+ 
Sbjct  117  FSYDWDREVNTTDPNYYKWTQWIFTKLYEK  146

1709) leuS in NC_017221


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  481 bits (1815),  Expect = 8e-137, Method: Compositional matrix adjust.
 Identities = 332/754 (45%), Positives = 477/754 (64%), Gaps = 73/754 (9%)

Query  234  LAYISKSPVNWCPGLGTVLANEEVTAEGKSERGNFPVFQRELRQWSMRITKYGHRLIADL  293
            LAY +  PVNW   LGT +ANEEV ++G SERG +PV ++ +RQW ++IT Y++RL+ DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  294  DGINWPEKVKLMQRNWIGESHGASVHFIVATADGDKDMEIYTTRPDTLFGTTFAVVSPEH  353
            + ++WPE +K MQRNWIG S GA+V F V   D DKD  ++TTRPDTLFG+T+AV++PEH
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKV--KDTDKDFTVFTTRPDTLFGATYAVLAPEH  265

Query  354  HLLENVPAEWPADVPEDWKGGYANPVEAVKAYRLAAEAKTAKDRVNEAGEKTGLFTGLYA  413
             L++ + +              ++  EAV  Y+  A  K+   R + A EKTG+ TG YA
Sbjct  266  ALVDAITT--------------SDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYA  311

Query  414  TNPITGAKLPLFTADYVLMDYGTGAIMAVPGGDQRDYDFAVKFGLPVIYTVTPLPDSGDD  473
             NP+ G  +P+  ADYVL  YGTGAIMAVP+ D+RD +FA +F L +I    P+ ++G+ 
Sbjct  312  INPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDII----PVLEGGN-  366

Query  474  LANYEGKAPFVSHDGIVINSSVEATEAKGDALSLNGLRVDDAIAKVNAWLESAGVGKGTV  533
                   A+F ++DG+ INS             L+GL    AIAK+  WLE+ GVG+  V
Sbjct  367  ----VEEAAF-TEDGLHINSDF-----------LDGLDKASAIAKMVEWLEAEGVGNENV  410

Query  534  SYRLRDWLFSRQRYWGEPFPIVYGEDGTPHLLPDSALPINLPDVPDYEPRTFDPMDAESN  593
            +YRLRDWLFSRQRYWGEP+PI+  EDGT+  +P+S LP+ LP   D  P         + 
Sbjct  411  TYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGT  462

Query  594  PEAPLSRNEDWVKVELDLGDGKKTYYRDTNTMPNWAGSCWYYMRYIDPTDTKHMVEKDEF  653
             E+PL+   DW+ V  + G   +   R+TNTMP+WAGS WYY+RYIDP +T  + + + +
Sbjct  463  GESPLANVTDWLEVTREDGVKGR---RETNTMPQWAGSSWYYLRYIDPHNTEKLADEELL  519

Query  654  DYWMGPNHNKYSGDEGGVDLYIGGVEHAVLHLLYSRFWHKVLFDLGYVDSAEPFHKLFNQ  713
              W+             VD+Y+GG EHAVLHLLY+RFWHKVL+DLG V + EPF+KLFNQ
Sbjct  520  KQWL------------PVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQ  567

Query  714  GMIQAYAYTDDRGQYVPADEVVEGPADASGEPTFTWNGEHANREFGKMGKSLKNIVTPDY  773
            GMI + +Y D RG  V++D V    +      T    GE+ ++  +KM+KSLKN+V PD 
Sbjct  568  GMILGTSYRDSRGALVATDKVEKRDGSFFHVET----GEELEQAPAKMSKSLKNVVNPDD  623

Query  774  MYENYGADTFRLYEMSMGPLDESRPWNTRNVVGGMRFLQRLWRNVVDETTGQAHVTEDTP  833
            + E+YGADT+R+YEM MGPLD S +W+   + G+ +FL+R+ R +        ++TE+ +
Sbjct  624  VVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTK-----EITEENS  678

Query  834  DEKTLKLLNNTIAEVTAEMEGMRPNTAIAKLIVLNNHLTGLKAVPRAAVEPLILMLAPIA  893
            +    K+ N+T+  VT +++ M+ NTAIA+L+V+ N       +       ++ ++AP+A
Sbjct  679  GALD-KVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFA  737

Query  894  PHICEEMWSKL-GHAESLSAEPWPVADERYVGHDTVTAVVQIKGKVRAKLEVPVDIDPAD  952
            PH+ EE+W  L + +ES+S  PWP  DE  + ++ V  VVQIKGKV+AKL V+ D+   +
Sbjct  738  PHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREE  797

Query  953  LEKQALAA--VADRLGGKEPRKVIVKAPKIVSIV  984
            L+  ALA   V   ++GK+  KVI  + K+V+IV
Sbjct  798  LQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIV  831


 Score =  137 bits (502),  Expect = 5e-33, Method: Compositional matrix adjust.
 Identities = 75/150 (50%), Positives = 104/150 (70%), Gaps = 12/150 (8%)

Query  25   IENKWQKIWDEQGTFWAANVNGDLKDGKGRNAEGRTAYFAMDMFPYPSGKGLHVGHPLGY  84
            IE KWQ +W ++ TF            K     ++  ++A+DMFPYPSG GLHVGHP GY
Sbjct  9    IEPKWQAFWADNHTF------------KTGTDASKPKFYALDMFPYPSGAGLHVGHPEGY  56

Query  85   LASDVVSRYHRMKGENVLHAMGYDAFGLPAEQYAVQTGQHPRVTTEANIANMSRQLHRMG  144
             A+D++SR+ R +G+NVLH+MG DAFGLPAEQYA++TG++P   T  NIAN  RQ++ +G
Sbjct  57   TATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALG  116

Query  145  LSFDNRRTFATIDPGYVRWTQWIFSRIYDS  174
            +S+D  R   T DP Y +WTQWIF+++Y+ 
Sbjct  117  FSYDWDREVNTTDPNYYKWTQWIFTKLYEK  146

1710) leuS in NC_004307


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  481 bits (1815),  Expect = 8e-137, Method: Compositional matrix adjust.
 Identities = 332/754 (45%), Positives = 477/754 (64%), Gaps = 73/754 (9%)

Query  234  LAYISKSPVNWCPGLGTVLANEEVTAEGKSERGNFPVFQRELRQWSMRITKYGHRLIADL  293
            LAY +  PVNW   LGT +ANEEV ++G SERG +PV ++ +RQW ++IT Y++RL+ DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  294  DGINWPEKVKLMQRNWIGESHGASVHFIVATADGDKDMEIYTTRPDTLFGTTFAVVSPEH  353
            + ++WPE +K MQRNWIG S GA+V F V   D DKD  ++TTRPDTLFG+T+AV++PEH
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKV--KDTDKDFTVFTTRPDTLFGATYAVLAPEH  265

Query  354  HLLENVPAEWPADVPEDWKGGYANPVEAVKAYRLAAEAKTAKDRVNEAGEKTGLFTGLYA  413
             L++ + +              ++  EAV  Y+  A  K+   R + A EKTG+ TG YA
Sbjct  266  ALVDAITT--------------SDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYA  311

Query  414  TNPITGAKLPLFTADYVLMDYGTGAIMAVPGGDQRDYDFAVKFGLPVIYTVTPLPDSGDD  473
             NP+ G  +P+  ADYVL  YGTGAIMAVP+ D+RD +FA +F L +I    P+ ++G+ 
Sbjct  312  INPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDII----PVLEGGN-  366

Query  474  LANYEGKAPFVSHDGIVINSSVEATEAKGDALSLNGLRVDDAIAKVNAWLESAGVGKGTV  533
                   A+F ++DG+ INS             L+GL    AIAK+  WLE+ GVG+  V
Sbjct  367  ----VEEAAF-TEDGLHINSDF-----------LDGLDKASAIAKMVEWLEAEGVGNENV  410

Query  534  SYRLRDWLFSRQRYWGEPFPIVYGEDGTPHLLPDSALPINLPDVPDYEPRTFDPMDAESN  593
            +YRLRDWLFSRQRYWGEP+PI+  EDGT+  +P+S LP+ LP   D  P         + 
Sbjct  411  TYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGT  462

Query  594  PEAPLSRNEDWVKVELDLGDGKKTYYRDTNTMPNWAGSCWYYMRYIDPTDTKHMVEKDEF  653
             E+PL+   DW+ V  + G   +   R+TNTMP+WAGS WYY+RYIDP +T  + + + +
Sbjct  463  GESPLANVTDWLEVTREDGVKGR---RETNTMPQWAGSSWYYLRYIDPHNTEKLADEELL  519

Query  654  DYWMGPNHNKYSGDEGGVDLYIGGVEHAVLHLLYSRFWHKVLFDLGYVDSAEPFHKLFNQ  713
              W+             VD+Y+GG EHAVLHLLY+RFWHKVL+DLG V + EPF+KLFNQ
Sbjct  520  KQWL------------PVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQ  567

Query  714  GMIQAYAYTDDRGQYVPADEVVEGPADASGEPTFTWNGEHANREFGKMGKSLKNIVTPDY  773
            GMI + +Y D RG  V++D V    +      T    GE+ ++  +KM+KSLKN+V PD 
Sbjct  568  GMILGTSYRDSRGALVATDKVEKRDGSFFHVET----GEELEQAPAKMSKSLKNVVNPDD  623

Query  774  MYENYGADTFRLYEMSMGPLDESRPWNTRNVVGGMRFLQRLWRNVVDETTGQAHVTEDTP  833
            + E+YGADT+R+YEM MGPLD S +W+   + G+ +FL+R+ R +        ++TE+ +
Sbjct  624  VVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTK-----EITEENS  678

Query  834  DEKTLKLLNNTIAEVTAEMEGMRPNTAIAKLIVLNNHLTGLKAVPRAAVEPLILMLAPIA  893
            +    K+ N+T+  VT +++ M+ NTAIA+L+V+ N       +       ++ ++AP+A
Sbjct  679  GALD-KVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFA  737

Query  894  PHICEEMWSKL-GHAESLSAEPWPVADERYVGHDTVTAVVQIKGKVRAKLEVPVDIDPAD  952
            PH+ EE+W  L + +ES+S  PWP  DE  + ++ V  VVQIKGKV+AKL V+ D+   +
Sbjct  738  PHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREE  797

Query  953  LEKQALAA--VADRLGGKEPRKVIVKAPKIVSIV  984
            L+  ALA   V   ++GK+  KVI  + K+V+IV
Sbjct  798  LQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIV  831


 Score =  137 bits (502),  Expect = 5e-33, Method: Compositional matrix adjust.
 Identities = 75/150 (50%), Positives = 104/150 (70%), Gaps = 12/150 (8%)

Query  25   IENKWQKIWDEQGTFWAANVNGDLKDGKGRNAEGRTAYFAMDMFPYPSGKGLHVGHPLGY  84
            IE KWQ +W ++ TF            K     ++  ++A+DMFPYPSG GLHVGHP GY
Sbjct  9    IEPKWQAFWADNHTF------------KTGTDASKPKFYALDMFPYPSGAGLHVGHPEGY  56

Query  85   LASDVVSRYHRMKGENVLHAMGYDAFGLPAEQYAVQTGQHPRVTTEANIANMSRQLHRMG  144
             A+D++SR+ R +G+NVLH+MG DAFGLPAEQYA++TG++P   T  NIAN  RQ++ +G
Sbjct  57   TATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALG  116

Query  145  LSFDNRRTFATIDPGYVRWTQWIFSRIYDS  174
            +S+D  R   T DP Y +WTQWIF+++Y+ 
Sbjct  117  FSYDWDREVNTTDPNYYKWTQWIFTKLYEK  146

1711) SVEN_2353 in NC_018750


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  481 bits (1814),  Expect = 9e-137, Method: Compositional matrix adjust.
 Identities = 356/743 (48%), Positives = 496/743 (67%), Gaps = 63/743 (8%)

Query  221  LAYASDAPVNWCPGLGTVLANEEVTADGRSERGNFPVFKSKLRQWNMRITAYadrllddl  280
            LAY ++ PVNW   LGT +ANEEV +DG SERG +PV +  +RQW ++ITAYA+RLL+DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  281  daldWPEAIKLQQRNWIGRSEGARVDFQVGDTG-AITVFTTRQDTLFGATYMVLAPEHPL  339
            + +DWPE+IK  QRNWIG+S GA V F+V DT+  +TVFTTR DTLFGATY VLAPEH+L
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  340  VDGAAKIVPAAWPEGTHDVWTGGHATPSEAVDAYRKQAASKSDVERQADAKEKTGVFTGA  399
            VD+ +                   +  +EAV  Y++QA+ KSD+ R   AKEKTGV TG+
Sbjct  268  VDAITT------------------SDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGS  309

Query  400  YATNPVSGEQIPVFIADYVLMGYGTGAIMAVPAHDSRDFAFARAFELPMRCVVQPADDRG  459
            YA NPV+G ++PV IADYVL +YGTGAIMAVPAHD RD  FA+ F+L +  V++ ++   
Sbjct  310  YAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVE-  368

Query  460  TDPSTWDEAFSSYEAELVNSSNEDITLDGLGVVEAKAKITAWLADRGIGEGTVNFRLRDW  519
                  + AF+  E  L  +S+    LDGL+   A AK+  WL   G+G+  V +RLRDW
Sbjct  369  ------EAAFT--EDGLHINSD---FLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDW  417

Query  520  LFSRQRYWGEPFPIVYDEDGVAHSlpesmlplelpeveDYSPRTFDPNDADTQPETPLSR  579
            LFSRQRYWGEP+PI+  EDG + ++PES LPL LP   D  P            E+PL+ 
Sbjct  418  LFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLAN  469

Query  580  NEDWVNVTLDLGDGAGPRRYRRETNTMPNWAGSCWYELRYLDPHNAEKLVDPAVEQYWMG  639
              DW++VT + G  +     RRETNTMP+WAGS WY LRY+DPHN+EKL D  + + W+ 
Sbjct  470  VTDWLEVTREDGVKG-----RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLP  524

Query  640  PREGMPTGGVDLYVGGAEHAVLHLLYARFWSKMLFDLGHISSAEPFHKLYNQGMIQAFVY  699
                     VD+YVGGAEHAVLHLLYARFW K+L+DLG +++ EPF+KL+NQGMI +  Y
Sbjct  525  ---------VDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY  575

Query  700  RDARGIAVPAAEVEERDGAFWY--EGEKVSRVLGKMGKSLKNAVTPDEICSEYGADTLRL  757
            RD+RG  V++  VE RDG+F     GE + +  +KM+KSLKN V PD++  +YGADTLR+
Sbjct  576  RDSRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRV  635

Query  758  YEMAMGPLDVSRPWDTRAVIGQYRLLQRLWRNIVDESTGEVTVVDTPADEDTLRALHKAI  817
            YEM MGPLD S +W   ++ G  ++L+R+ R I   +T E+T  ++ A +   +  + ++
Sbjct  636  YEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLI---TTKEITEENSGALD---KVYNETV  689

Query  818  DGVAQDMVAMRFNTAIAKITELNNHLTKSGGAISRQVAEQLVLLVAPLAPHISEELWRKL  877
             +V++++  M+FNTAIA++  + N   K +  +S + A  +V L+AP+APH++EELW+ L
Sbjct  690  KAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFS-DYAKGFVQLIAPFAPHLGEELWQAL  748

Query  878  -GHTDSVVHQDFPVADPAYVVDETVTCVVQIKGKVKARLEVSPSITdadlealaladPHV  936
             +  +S+     P  D + +V++ V  VVQIKGKVKA+L V+  ++  +L+ +ALA+  V
Sbjct  749  TASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKV  808

Query  937  VAALGGAEIRKVVVRAPKLVNIV  959
             A ++G +I KV+  + KLVNIV
Sbjct  809  QAEIAGKDIIKVIAVPNKLVNIV  831


 Score =  136 bits (499),  Expect = 8e-33, Method: Compositional matrix adjust.
 Identities = 76/150 (51%), Positives = 101/150 (68%), Gaps = 10/150 (6%)

Query  22   ADIEARWQDFWDAEGTYEAPNPAGDLAGDPAVAARPKKFIMDMFPYPSGAGLHVGHPLGY  81
            + IE++WQ FW  + T+ +   A          ++PK + +DMFPYPSGAGLHVGHP GY
Sbjct  7    TAIEPKWQAFWADNHTFKTGTDA----------SKPKFYALDMFPYPSGAGLHVGHPEGY  56

Query  82   IATDVFARHARMTGHNVLHTLGFDAFGLPAEQYAVQTGTHPRVSTEANMENMKVQLRRLG  141
             ATD+++R  R  GHNVLH +G DAFGLPAEQYA++TG +P   T  N+ N K Q+  LG
Sbjct  57   TATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALG  116

Query  142  LGHDKRRSFATIDPDYYKWTQWIFLQIYNS  171
            ++ D  R   T DP+YYKWTQWIF ++Y+ 
Sbjct  117  FSYDWDREVNTTDPNYYKWTQWIFTKLYEK  146

1712) Intca_1421 in NC_014830


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  481 bits (1814),  Expect = 9e-137, Method: Compositional matrix adjust.
 Identities = 347/757 (46%), Positives = 489/757 (65%), Gaps = 75/757 (9%)

Query  228  LAYRSEAPVNWCPGLGTVLSNEEVTNEGRSERGNFPVFRRNLSQWMMRITAYadrladdl  287
            LAY +E PVNW   LGT ++NEEV  +G SERG +PV R+ + QWM++ITAYA+RL +DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  288  drVDWPEKVKLMQRNWIGRSQGARVRFPVVTVAGDKTDIEVFTTRPDTLFGATFMVIAPE  347
            + VDWPE +K MQRNWIG+S GA V F    V +   D+ VFTTRPDTLFGAT+ V+APE
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTF---KVKDTDKDFTVFTTRPDTLFGATYAVLAPE  264

Query  348  HPLVDRLVPEGDWPDGTHEDWRGADpvaaatprsavaaYQLAASRKGDVERQTEGKDKTG  407
            H+LVD +   ++ +++  +                   Y+  AS K+D+ R   +K+KTG
Sbjct  265  HALVDAITTSDQ-AEAVAD-------------------YKRQASLKSDLARTDLAKEKTG  304

Query  408  VFTGSWATNPLNGEAIPVFVADYVLMGYGTGAIMAVPGHDVRDFEYATKFSLPIRRVVAP  467
            V TGS A NP+NG  +PV +ADYVL +YGTGAIMAVP+HD RD E+A +F+L I  V+  
Sbjct  305  VWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL--  362

Query  468  SVEEADGPLEEAFVGAGLAVNSANDHVDLNGLALDEAKERIIEALERDGIGEGAVTYRIR  527
               E++   E AF   GL +NS      L+GL    A  +++E LE +G+G+  VTYR+R
Sbjct  363  ---EGGNVEEAAFTEDGLHINSDF----LDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  528  DWLFSRQRYWGEPFPIMFDEDGVSYPVLEDELPLTLPEVPDYSPKTFDPDDATSSPEPPL  587
            DWLFSRQRYWGEP+PI+  EDG S +V E ELPL LP   D  P        +++ E+PL
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPL  467

Query  588  SRVPEWVNVEADLGDGRGMRRFRRETNTMPNWAGSCWYYFRYLDPANDEKFVDPANEAYW  647
            + V +W++V  + ++ +G    RRETNTMP+WAGS WYY+RY+DP N EK+ D      W
Sbjct  468  ANVTDWLEVTRE-DGVKG----RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQW  522

Query  648  LAKQaapvagapagTLDPGGVDLYVGGVEHAVLHLLYARFWHKVLFDLGHVQSEEPFRKY  707
            L+                  VD+YVGG EHAVLHLLYARFWHKVL+DLG V + EPF+K 
Sbjct  523  LP------------------VDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKL  564

Query  708  FSQGYIQAYAYTDSRGQYVPAAEVEEQPGAQGAESTFSWRGEPVNREYGKIGKSLKNSVS  767
            F+QG I + +Y DSRG  V++  VE + G+     T    GE +++  +K++KSLKN V+
Sbjct  565  FNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVET----GEELEQAPAKMSKSLKNVVN  620

Query  768  PDEMYDAYGADTFRLYEMSMGPLELSKPWETRAVVGSQRFLQRLWRNVVDEVTGDVRVAD  827
            PD++ + YGADT+R+YEM MGPL+ S +W   ++ GS++FL+R+ R +      +     
Sbjct  621  PDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITE-----  675

Query  828  IAPDQALTTQLHRTIAGVREDFEGLRFNTAIAKLIELNNAVTKLDVPPREVMEALVLMIA  887
                 AL    + T+ +V E+ + ++FNTAIA+L+ + NA  K D    +   ++V +IA
Sbjct  676  -ENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIA  734

Query  888  PVAPHIAEELWSRLGHPG-GVSYVPFPVSDASKIVEEQVTCVIQIKGKVRDRVEVPPDIS  946
            P APH++EELW  L  +G ++SYVP P  D SK+VE++V  V+QIKGKV+ ++ V+ D+S
Sbjct  735  PFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLS  794

Query  947  EDDLRELALSREKVRVATES-GIRTVIVRAPKLVNVV  982
             ++L+E+AL+ EKV+    + +I  VI  + KLVN+V
Sbjct  795  REELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIV  831


 Score =  122 bits (447),  Expect = 1e-28, Method: Compositional matrix adjust.
 Identities = 75/148 (51%), Positives = 99/148 (67%), Gaps = 11/148 (7%)

Query  20   AAIEVAWQDRWEEQGTFDAPNPAGPWAQPDEVAQRGEKLVVLDMFPYPSGAGLHVGHPLG  79
            +AIE  WQ  W ++ TF +   A+             K+  LDMFPYPSGAGLHVGHP G
Sbjct  7    TAIEPKWQAFWADNHTFKTGTDASK-----------PKFYALDMFPYPSGAGLHVGHPEG  55

Query  80   YIATDVYSRLHRMLGKNVLHALGYDAFGLPAEQFAVQTGQHPRKTTEENMTVMRRQLRRL  139
            Y ATD+ SR+ R  G NVLH++G DAFGLPAEQ+A++TG++P   T EN++  +RQ+  L
Sbjct  56   YTATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINAL  115

Query  140  GLGFDNRRTFATIDENYYKWTQWIFLQI  167
            G+++D  R   T D NYYKWTQWIF ++
Sbjct  116  GFSYDWDREVNTTDPNYYKWTQWIFTKL  143

1713) NH8B_3906 in NC_016002


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  481 bits (1813),  Expect = 9e-137, Method: Compositional matrix adjust.
 Identities = 360/879 (41%), Positives = 551/879 (63%), Gaps = 61/879 (6%)

Query  5    YSPREIEADAQQKWQRTAAFKAVEDTSRPKYYALSMFPYPSGK-LHMGHVRNYTITDVLA  63
            Y    IE+  Q  W    +FK+  D+S+PK+YAL MFPYPSG  LH+GH   YT TD+L+
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RFKRFQGYNVLQPMGWDAFGLPAENAAMKSGGAPAAWTYANIDYMKKQLDSLGFALDWER  123
            RFKR QG NVL+PMGWDAFGLPAE+ AM +G  PA  T  NI   K+Q+++LGF+ DW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCKPDYYRWEQWLFTKLFEKGVIYKKNGVVNWDPVDHTVLANEQVI-DGRGWRSGAL  182
            E+ T  P+YY+W QW+FTKL+EKG+ Y  +  VNW     T +ANE+V+ DG + R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VEKREIPMYYFAITQYADELLTSLDTLDGWPEQVKTMQKNWIGKSFGAEIVFPYDEASVG  242
            V ++ +    + IT YA+ LL  L+ +D WPE +K MQ+NWIGKS GA++ F   ++   
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDT---  239

Query  243  HGGELKVYTTRPDTLMGATYVAVAAEHPLATQAAASHPELQAFIAECKAGSVAEADMA--  300
             + ++ V+TTRPDTL GATY  +A+EH+L    ++S+      +A+ K  +   +D+A  
Sbjct  240  -DKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQA--EAVADYKRQASLKSDLART  296

Query  301  --TMEKKGMPTGLSVVHPLTGDTLPVWVANYVLWGYGEGAVMAVPAHDERDFAFANKYAL  358
              + EK G+ TG   ++P+ G  +PVW+A+YVL +YG GA+MAVPAHDERD  FA+++ L
Sbjct  297  DLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNL  356

Query  359  PIKQVIAKRDGDNDFDATVWREWYADKDDSVKTVNSGKYDGLGYqaafdaivadlaaqaH  418
             I  V+   + ++           A  +D++  +NS+  DGL+  +A+  +V  L A++ 
Sbjct  357  DIIPVLEGGNVEEA----------AFTEDGLH-INSDFLDGLDKASAIAKMVEWLEAEGV  405

Query  419  GTKKTQYRLRDWGISRQRYWGcpipiihcpccGDVPVPADQLPVVLP--ENVVPDGAG-S  475
            G  +  YRLRDW +SRQRYWG PIPIIH       +VP  +LP+VLP   ++ P G+G S
Sbjct  406  GNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGES  465

Query  476  PLAKMPEFYETACPKCGGAAKRETDTMDTFVESSWYYARYASPKCDTAMVDKHAADYWLQ  535
            PLA++ +  E +    G  ++RET+TM     SSWYY RY  P     + D +    WL 
Sbjct  466  PLANVTDWLEVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLP  524

Query  536  VDQYVGGIEHAILHLLYARFFHKLMRDEGLVSSDEPFKSLLTQGMVVCETFYRDLPNGSK  595
            VD YVGG EHA+LHLLYARF HK++ D G+V++ EPF+ L+ QGM++  + YRD   +  
Sbjct  525  VDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS-YRDSRGA--  581

Query  596  DWIAPQDVVLERDGKGKIVAATHRVDGQPVAIGGIEKMSKSKNNGVDPQEFIEKYGADTA  655
              + + D V  RDG    V + + ++  P       KMSKS +N V+P++ +E+YGADT 
Sbjct  582  --LVATDKVEKRDGSFFHVETGEELEQAP------AKMSKSLKNVVNPDDVVEQYGADTL  633

Query  656  RLFMMFAAPPEQSLEWSDAGVEGAFRFLKRLWKVVKDHTDGGVVAAYRGGELDAGLKELR  715
            R++ MF +P + S+ WS+ G+EG+ +FL R+ +++        ++   +G LD       
Sbjct  634  RVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKE----ITEENSGALD-------  682

Query  716  FKLHGTIQKVADDYGRRQQFNTAIAAVMELLNTYDKADRS-SDAGRAVAQEVLEAAVILL  774
             K+     K   +   + +FNTAIA +M ++N+ +K D+  SD +++  Q        L+
Sbjct  683  -KVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQ--------LI  733

Query  775  SPIVPHITDALWNALQPGSELLA-QAWPKVDEAALVKSEIELMVQVNGKLRGSVTVaada  833
            +P+ PH+ + LW+AL +++E ++  +WP  DE+ LV +++E++VQ++GK+++ + VA D 
Sbjct  734  APFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDL  793

Query  834  akdaieaaamandNVQKFMEGKPAKKVIVVPGRLVNIVV  872
            +++ ++  A+AN++VQ  + GK   KVI VP +LVNIV+
Sbjct  794  SREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832

1714) leuS in NC_014246


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  480 bits (1811),  Expect = 2e-136, Method: Compositional matrix adjust.
 Identities = 344/752 (46%), Positives = 486/752 (65%), Gaps = 73/752 (9%)

Query  226  LAYVAYAPVNWAPGLGTVLADEEVTAEGRSERGNFPVFKTKLRQWMMRITRYADRLDADL  285
            LAY A  PVNW   LGT +A+EEV ++G SERG +PV +  +RQWM++IT YA+RL  DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  286  ATIDWPDKVRTMQHNWIGKSFGATVNFQVEAGQGPQPQTLQVFTTRPDTLFGATFMVISP  345
              +DWP+ ++ MQ+NWIGKS GA V F+V   +    + + VFTTRPDTLFGAT+ V++P
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD----KDFTVFTTRPDTLFGATYAVLAP  263

Query  346  EHPLVGAEDCADTELQVPDTWPEGTRPEWTGGYATPREAVAAYRAQASAKSDSERTAETD  405
            EH+LV+A   +D                         EAVA Y+ QAS KSD  RT  + 
Sbjct  264  EHALVDAITTSDQA-----------------------EAVADYKRQASLKSDLARTDLA-  299

Query  406  FTEKTGVFTGIFGTNPVNSSLVPIFVADYVLMGYGTGAIMAVPAHDERDHAFARKFNLDI  465
              EKTGV TG ++ NPVN+  +P+ +ADYVL +YGTGAIMAVPAHDERD  FA++FNLDI
Sbjct  300  -KEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDI  358

Query  466  IQTISGPDGLDVQEEPWTGDGVIENSANSEISLNGLGKAEAIAKISDWLAQTGRGEKTVT  525
            I  + G +   V+E + T DG+     NS++ L+GL+KA AIAK+ +WL   G G+  VT
Sbjct  359  IPVLEGGN---VEEAAFTEDGL---HINSDF-LDGLDKASAIAKMVEWLEAEGVGNENVT  411

Query  526  YRLRDWLFSRQRYWGEPFPVVYGSDGRVHAlpeemlplelpeVSDFRPRTFDPDDAHSTP  585
            YRLRDWLFSRQRYWGEP+P++   DG   A+PE  LPL LP   D+RP         +T 
Sbjct  412  YRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPS--------GTG  463

Query  586  ESPLGRATDWMTVELDLGEGKQTYTRDQNTMPNWAGSCWYELRYTDPDNPTAFASTDNEA  645
            ESPL+  TDW+ V  + G   +   R+ NTMP+WAGS WY LRY DP+N   +A  +   
Sbjct  464  ESPLANVTDWLEVTREDGVKGR---RETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLK  520

Query  646  YWMGPRPAAGNLSGGTDLYVGGVEHAVLHLLYARFWHKVLYDLGYVSSSEPFHRLFNQGM  705
             W+             D+YVGG EHAVLHLLYARFWHKVLYDLG V++ EPF++LFNQGM
Sbjct  521  QWLP-----------VDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGM  569

Query  706  IEAYAYTDSRGQYVPADEVEGSEEDGFTWQ-GQPVNREFGKMGKSLKNIVTPDQMCADYG  764
            I + +Y DSRG  V++D VE  +   F  + G+ +++  +KM+KSLKN+V PD++  +YG
Sbjct  570  ILGTSYRDSRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYG  629

Query  765  ADTFRVYEMSMGPLDMSRPWDTRAVVGSQRFLQRLWRNIVDENTGTLTVTDDAPDLATAK  824
            ADT+RVYEM MGPLD S +W   ++ GS++FL+R+ R I   +     +T++ ++ A  K
Sbjct  630  ADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKE-----ITEENSG-ALDK  683

Query  825  VLARTIHDVTVEYDNLRVNTAIAKMIVLNNHLTGLPQVPREAAEALVVMVAPIAPHIAEE  884
            V   T+  VT + D+++ NTAIA+++V+ N      ++  + A ++V ++AP+APH++EE
Sbjct  684  VYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEE  743

Query  885  LWERLGHQGG----IARATFPVVTDESLLAAEEVTCVVQVAGKVRAKVSVDPEISEADLQ  940
            LW+ L   G     ++++++    DES L  ++V  VVQ+ GKV+AK+ V  ++S  +LQ
Sbjct  744  LWQALTASGESISYVPWPSY----DESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQ  799

Query  941  AKVLAEPAVVKLLDGREPKRIIVRAPKLVSLV  972
               LA+  V   + G++  ++I  + KLV++V
Sbjct  800  EVALANEKVQAEIAGKDIIKVIAVPNKLVNIV  831


 Score =  142 bits (523),  Expect = 1e-34, Method: Compositional matrix adjust.
 Identities = 76/148 (52%), Positives = 108/148 (73%), Gaps = 8/148 (5%)

Query  22   GNLEAKWQRIWDETGAFNADNPSGPLAGDLAKREKYFILDMFPYPSGKGLHVGHPLGYIA  81
              +E+KWQ +W +  +F+++  ++        + K++ LDMFPYPSG GLHVGHP GY A
Sbjct  7    TAIEPKWQAFWADNHTFKTGTDAS--------KPKFYALDMFPYPSGAGLHVGHPEGYTA  58

Query  82   TDVVARYHRAQGKNVLYTMGYDAFGLPAEQYALQTGQHPAITTHDNIANMSKQLARIGLS  141
            TD+++R+ RAQG NVL  MG DAFGLPAEQYA++TG++PA  T +NIAN  +Q+  +G+S
Sbjct  59   TDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFS  118

Query  142  HDRRRSFATTDPNYFKWTQWIFLQIFNS  169
             D+ R   TTDPNY+KWTQWIF ++++ 
Sbjct  119  YDWDREVNTTDPNYYKWTQWIFTKLYEK  146

1715) leuS in NC_016582


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  480 bits (1808),  Expect = 3e-136, Method: Compositional matrix adjust.
 Identities = 352/740 (48%), Positives = 485/740 (66%), Gaps = 59/740 (7%)

Query  219  LAYASDAPVNWCPGLGTVLANEEVTAEGRSERGNFPVFKANLRQWNMRITayadrllddl  278
            LAY ++ PVNW   LGT +ANEEV ++G SERG +PV +  +RQW ++ITAYA+RLL+DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  279  ealdWPEAIKLQQRNWIGRSEGARVDFPVADHPDAKITIFTTRQDTLFGATYMVLAPEHG  338
            E +DWPE+IK  QRNWIG+S GA V F V D  D  +T+FTTR DTLFGATY VLAPEH+
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKD-TDKDFTVFTTRPDTLFGATYAVLAPEHA  266

Query  339  LVDAIVPAAWPEGTHDVWTGGHSTPaeavaayrkqaaaKSDVERQAEVKDKTGVFIGAYA  398
            LVDAI  +  +E+  D               Y++QA+ KSD+ R    K+KTGV  G+YA
Sbjct  267  LVDAITTSDQAEAVAD---------------YKRQASLKSDLARTDLAKEKTGVWTGSYA  311

Query  399  TNPVNGDRIPVFIADYVLMGYGTGAIMAVPAGDQRDFEFARAFELPIRCIVEPTDGRGTD  458
             NPVNG  +PV IADYVL +YGTGAIMAVPA D+RD EFA+ F+L I  ++E  +     
Sbjct  312  INPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEE--  369

Query  459  TTTWVDAFGSYDAKIINSAGEGISLDGLGVVEAKARMAEWLTARGIGEGTVNFRLRDWLF  518
                    +++    ++  ++   LDGL+   A A+M EWL A G+G+  V +RLRDWLF
Sbjct  370  --------AAFTEDGLHINSD--FLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLF  419

Query  519  SRQRYWGEPFPIVYDEDGVAHplpesmlplelpeveDYSPRTFDPDDADTSPETPLSRNE  578
            SRQRYWGEP+PI+  EDG + ++PES LPL LP   D  P          + E+PL+   
Sbjct  420  SRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVT  471

Query  579  DWVHVELDLGDGAGPKRYRRETNTMPNWAGSCWYELRYLDPHNAERLVDPDIEQYWMGPR  638
            DW    L++    G K  RRETNTMP+WAGS WY LRY+DPHN+E+L D ++ + W+   
Sbjct  472  DW----LEVTREDGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLP--  524

Query  639  EGQPTGGVDLYVGGAEHAVLHLLYARFWSKVLYDLGHISSAEPFHKLYNQGMIQAYVYRD  698
                   VD+YVGGAEHAVLHLLYARFW KVLYDLG +++ EPF+KL+NQGMI +  YRD
Sbjct  525  -------VDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRD  577

Query  699  SRGIAVPAAEVEERDGAYYY--QGEKVTRLLGKMGKSLKNAVTPDEICAEYGADTLRLYE  756
            SRG  V++  VE RDG+++    GE + +  +KM+KSLKN V PD++  +YGADTLR+YE
Sbjct  578  SRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYE  637

Query  757  MAMGPLDVSRPWDTRAVVGQYRLLQRLWRNAVDEASGEVTVVDAEPDEATLRALHKAIDG  816
            M MGPLD S +W   ++ G  ++L+R+ R            +  E   A  +  + ++ +
Sbjct  638  MFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKE------ITEENSGALDKVYNETVKA  691

Query  817  VRQDMVNLRFNTAIAKITELNNHVTKAPEVPRQVAEALVLLIAPLAPHIAEELWRKL-GH  875
            V +++ +++FNTAIA++  + N   K   +  + A ++V LIAP+APH++EELW+ L + 
Sbjct  692  VTEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTAS  751

Query  876  DTSVVHEPFPVADPAYVIDETVTCVVQVKGKVKARLEVAPSVSEEELEKLALGDPAVVAA  935
            + S+   P P  D + ++++ V  VVQ+KGKVKA+L VA  +S EEL+ +AL++  V A 
Sbjct  752  GESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAE  811

Query  936  LNGAGIRKVIVRAPKLVNIV  955
            + G +I KVI  + KLVNIV
Sbjct  812  IAGKDIIKVIAVPNKLVNIV  831


 Score =  140 bits (516),  Expect = 4e-34, Method: Compositional matrix adjust.
 Identities = 75/150 (50%), Positives = 103/150 (69%), Gaps = 10/150 (6%)

Query  21   ADIEARWQDFWDAQGTYDASNPSGELAGDPEAVARPKKFVMDMFPYPSGAGLHVGHPLGY  80
            + IE++WQ FW  + T+ ++  +          ++PK + +DMFPYPSGAGLHVGHP GY
Sbjct  7    TAIEPKWQAFWADNHTFKTGTDA----------SKPKFYALDMFPYPSGAGLHVGHPEGY  56

Query  81   IATDVYARYHRMTGHNVLHTLGFDAFGLPAEQYAVQTGTHPRVSTEANIENMRRQLRRLG  140
             ATD+ +R+ R  GHNVLH +G DAFGLPAEQYA++TG +P   T  NI N +RQ+  LG
Sbjct  57   TATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALG  116

Query  141  LGHDPRRSFATIDPDYYKWTQWIFLQIFNS  170
            ++ D  R   T DP+YYKWTQWIF ++++ 
Sbjct  117  FSYDWDREVNTTDPNYYKWTQWIFTKLYEK  146

1716) BLIF_1140 in NC_015052


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  479 bits (1807),  Expect = 3e-136, Method: Compositional matrix adjust.
 Identities = 332/754 (45%), Positives = 476/754 (64%), Gaps = 73/754 (9%)

Query  234  LAYISKSPVNWCPGLGTVLANEEVTAEGKSERGNFPVFQRELRQWSMRITKYGHRLIADL  293
            LAY +  PVNW   LGT +ANEEV ++G SERG +PV ++ +RQW ++IT Y++RL+ DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  294  DGINWPEKVKLMQRNWIGESHGASVHFIVATADGDKDMEIYTTRPDTLFGTTFAVVSPEH  353
            + ++WPE +K MQRNWIG S GA+V F V   D DKD  ++TTRPDTLFG+T+AV++PEH
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKV--KDTDKDFTVFTTRPDTLFGATYAVLAPEH  265

Query  354  HLLENVPAEWPADVPEDWKGGYANPVEAVKAYRLAAEAKTAKDRVNEAGEKTGLFTGLYA  413
             L++ + +              ++  EAV  Y+  A  K+   R + A EKTG+ TG YA
Sbjct  266  ALVDAITT--------------SDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYA  311

Query  414  TNPITGAKLPLFTADYVLMDYGTGAIMAVPGGDQRDYDFAVKFGLPVIYTVTPLPDSGDD  473
             NP+ G  +P+  ADYVL  YGTGAIMAVP+ D+RD +FA +F L +I    P+ ++G+ 
Sbjct  312  INPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDII----PVLEGGN-  366

Query  474  LANYEGKAPFVSHDGIVINSSVEATEAKGDALSLNGLRVDDAIAKVNAWLESAGVGKGTV  533
                   A+F ++DG+ INS             L+GL    AIAK+  WLE+ GVG+  V
Sbjct  367  ----VEEAAF-TEDGLHINSDF-----------LDGLDKASAIAKMVEWLEAEGVGNENV  410

Query  534  SYRLRDWLFSRQRYWGEPFPIVYGEDGTPHLLPDSALPINLPDVPDYEPRTFDPMDAESN  593
            +YRLRDWLFSRQRYWGEP+PI+  EDGT+  +P+S LP+ LP   D  P         + 
Sbjct  411  TYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGT  462

Query  594  PEAPLSRNEDWVKVELDLGDGKKTYYRDTNTMPNWAGSCWYYMRYIDPTDTKHMVEKDEF  653
             E+PL+   DW+ V  + G   +   R+TNTMP+WAGS WYY+RYIDP +T  + + + +
Sbjct  463  GESPLANVTDWLEVTREDGVKGR---RETNTMPQWAGSSWYYLRYIDPHNTEKLADEELL  519

Query  654  DYWMGPNHNKYSGDEGGVDLYIGGVEHAVLHLLYSRFWHKVLFDLGYVDSAEPFHKLFNQ  713
              W+             VD+Y+GG EHAVLHLLY+RFWHKVL+DLG V + EPF+KLFNQ
Sbjct  520  KQWL------------PVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQ  567

Query  714  GMIQAYAYTDDRGQYVPADEVVEGPADASGEPTFTWNGEHANREFGKMGKSLKNIVTPDY  773
            GMI + +Y D RG  V++D V    +      T    GE+ ++  +KM+KSLKN+V PD 
Sbjct  568  GMILGTSYRDSRGALVATDKVEKRDGSFFHVET----GEELEQAPAKMSKSLKNVVNPDD  623

Query  774  MYENYGADTFRLYEMSMGPLDESRPWNTRNVVGGMRFLQRLWRNVVDETTGQAHVTEDTP  833
            + E+YGADT+R+YEM MGPLD S +W+   + G+ +FL+R+ R +        ++TE+ +
Sbjct  624  VVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTK-----EITEENS  678

Query  834  DEKTLKLLNNTIAEVTAEMEGMRPNTAIAKLIVLNNHLTGLKAVPRAAVEPLILMLAPIA  893
            +    K+ N+T+  VT +++ M+ NTAIA+L+V+ N       +       ++ ++AP+A
Sbjct  679  GALD-KVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFA  737

Query  894  PHICEEMWSKL-GHAESLSAEPWPVADERYVGYDTVTAVVQIKGKVRAKLEVPVDIDPAD  952
            PH+ EE+W  L + +ES+S  PWP  DE  +  + V  VVQIKGKV+AKL V+ D+   +
Sbjct  738  PHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREE  797

Query  953  LEKQALAA--VADRLGGKEPRKVIVKAPKIVSIV  984
            L+  ALA   V   ++GK+  KVI  + K+V+IV
Sbjct  798  LQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIV  831


 Score =  137 bits (502),  Expect = 5e-33, Method: Compositional matrix adjust.
 Identities = 75/150 (50%), Positives = 104/150 (70%), Gaps = 12/150 (8%)

Query  25   IENKWQKIWDEQGTFWAANVNGDLKDGKGRNAEGRTAYFAMDMFPYPSGKGLHVGHPLGY  84
            IE KWQ +W ++ TF            K     ++  ++A+DMFPYPSG GLHVGHP GY
Sbjct  9    IEPKWQAFWADNHTF------------KTGTDASKPKFYALDMFPYPSGAGLHVGHPEGY  56

Query  85   LASDVVSRYHRMKGENVLHAMGYDAFGLPAEQYAVQTGQHPRVTTEANIANMSRQLHRMG  144
             A+D++SR+ R +G+NVLH+MG DAFGLPAEQYA++TG++P   T  NIAN  RQ++ +G
Sbjct  57   TATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALG  116

Query  145  LSFDNRRTFATIDPGYVRWTQWIFSRIYDS  174
            +S+D  R   T DP Y +WTQWIF+++Y+ 
Sbjct  117  FSYDWDREVNTTDPNYYKWTQWIFTKLYEK  146

1717) leuS in NC_009446


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  479 bits (1807),  Expect = 3e-136, Method: Compositional matrix adjust.
 Identities = 344/858 (41%), Positives = 539/858 (63%), Gaps = 61/858 (7%)

Query  24   FKAVVNPQKEKFYCLSMFPYPSGK-LHMGHVRNYTIGDVISRYQRMLGKNVLQPMGWDAF  82
            FK+  ++ K KFY L MFPYPSG  LH+GH   YT  D++SR++R  G NVL+PMGWDAF
Sbjct  23   FKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSRFKRAQGHNVLHPMGWDAF  82

Query  83   GMPAENAAMKNQVAPAQWTYQNIAEMKKQLQSLGFAIDWSREITTCRPDYYRWEQWLFTR  142
            G+PAE+ AM     PA+ T +NIA+ K+Q+++LGF+ DW RE+ T  P+YY+W QW+FT+
Sbjct  83   GLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTK  142

Query  143  LYQKGVIYRKLGAVNWDPVDQTVLANEQVI-DGRGWRSGAIVEKREIPMYYFRITDYAEE  201
            LY+KG+ Y    +VNW     T +ANE+V+ DG + R+G  V ++ +    ++IT YAE 
Sbjct  143  LYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAER  202

Query  202  LLNDLEQLDGWPERVKMMQRNWIGKSRGMTIRFPIEPESQKGLSAENAQFLQIYTTRPDT  261
            LL+DLE++D WPE +K MQRNWIGKS G  + F +  +++K+++        ++TTRPDT
Sbjct  203  LLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVK-DTDKDFT--------VFTTRPDT  252

Query  262  IFGVTFl--avaaehplalaaaEDNPALRQFMTECK-TGSVAEADLATMPKKGMATGRFV  318
            +FG T+   A       A++++++  A+ ++  +    + +A +DLA   K G+ TG + 
Sbjct  253  LFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA-KEKTGVWTGSYA  311

Query  319  THPLTGKRLPVWVGNYVLSGYGDAAVMGVPAHDERDFHFAHQYGLPIVQVIQTEK-DLPA  377
             +P+ GK +PVW+++YVL++YG +A+M+VPAHDERD +FA Q+ L I+ V++  + + +A
Sbjct  312  INPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEAA  371

Query  378  FNADSWQEWYGDKEEMHVIASDDCNGLNYDQAFEKLSEKLAALNLGEPKTQYRLRDWGIS  437
            F  D+          +H I SD  +GL+   A+ K+ E L A  +G+ +  YRLRDW +S
Sbjct  372  FTEDG----------LH-INSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  438  RQRYWGCPIPIIHHDDGEALA---DTLPVVLP---EDKIPDGGGSVLAQSPDYYE-CRFQ  490
            RQRYWG PIPIIH +DG + A     LP+VLP   + + ++ G S LA+  D  E  R +
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED  480

Query  491  GKAARRETDTMDTFVESSWYQFRYMSPHYQKGMLDPEEVAYWQDVDQYIGGIEHAILHLL  550
            G  +RRET+TM     SSWY +RY+ PH    + D E +  W  VD Y+GG EHA+LHLL
Sbjct  481  GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLL  540

Query  551  YARFFTKLLRDEGLVHTDEPFKKLLTQGMVLAGTWYREQEHGSKIWFNPADVQVKTDDKG  610
            YARF  K+L D G+V T EPF+KL+ QGM+L+ + YR+  +G+ +      V+ + +   
Sbjct  541  YARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS-YRD-SRGALV--ATDKVEKRDGSFF  596

Query  611  RIIGGVLLSDGKPVQYGGMEKMSKSKNNGVDPQALIKTYGADTARLYTMFTAPPEASLEW  670
            ++  G  L ++ +       KMSKS +N V+P+ ++  YGADT R+Y MF +P +AS+ W
Sbjct  597  HVETGEELEQAPA-------KMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAW  649

Query  671  SESGVEGAYRFLRRLWAYCYEFRHSIAKPSEVVPLNEKHQNIRREIHEQLRAARFDYERN  730
            SE G+EG+ +FL R+      +R   +K       +E+   + +  +E ++A   + ++ 
Sbjct  650  SEEGLEGSRKFLDRV------YRLITTKEIT----EENSGALDKVYNETVKAVTEQVDQM  699

Query  731  QFNTVVSAGMKLFNCLNEIEPDYDALRREGVRILLLILSPIVPHITETLWQALDFSG-VI  789
            +FNT ++  M + N  N  +  +    +     ++ +++P+ PH+ E LWQAL  SG  I
Sbjct  700  KFNTAIAQLMVFVNAANKEDKLFSDYAKG----FVQLIAPFAPHLGEELWQALTASGESI  755

Query  790  SDQALPEVDETALKQDNMTLVVQINGKRRGEISVATDAAQQNIIDCALADERFAPYLAGL  849
            S  + P  DE+ L ++++ +VVQI+GK ++ + VA D +++++ + ALA+E+  + +AG 
Sbjct  756  SYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGK  815

Query  850  TVQKTIYVPKKLVNIVAK  867
             + K I VP+KLVNIV K
Sbjct  816  DIIKVIAVPNKLVNIVIK  833

1718) leuS in NC_017456


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  479 bits (1806),  Expect = 4e-136, Method: Compositional matrix adjust.
 Identities = 336/755 (45%), Positives = 481/755 (64%), Gaps = 74/755 (9%)

Query  239  IAYISKSPVNWCPGLGTVLANEEVTAEGKSERGNFPVFQRNLRQWSMRITAYAHRLVEDL  298
            +AY +  PVNW   LGT +ANEEV ++G SERG +PV ++ +RQW ++ITAYA+RL+EDL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  299  DTIDWPEKVKLMQRNWIGESHGASVHFEVECADGEMRDLEVYTTRPDTLFGTTFAVVSVD  358
            + +DWPE +K MQRNWIG S GA+V F V  +D   +D+ V+TTRPDTLFG+T+AV++ +
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD---KDFTVFTTRPDTLFGATYAVLAPE  264

Query  359  HPILEHVPEAWEASVPESWKGGYASLKEGLAEYQAQARAKTAKDRTEDAGAKTGLFTGLY  418
            H++++ +                +   E++A+Y+ QA  K+   RT+ A  KTG+ TG Y
Sbjct  265  HALVDAITT--------------SDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSY  310

Query  419  AINPVTGAKLPLFVADYVLMGYGTGAIMAVPGGDQRDYDFAKAFGLSVIYTVKPLPDSVE  478
            AINPV G  +P+ +ADYVL +YGTGAIMAVP+ D+RD +FAK F L +I    P+ ++  
Sbjct  311  AINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDII----PVLEG-G  365

Query  479  KLEDYDGKAPFVSHDGIVINSSVEHTYKLGDALSINGLRVDEAIKKVTTWLEAAGVGVGK  538
            ++E+    A+F ++DG+ INS             ++GL    AI K+  WLEA GVG  +
Sbjct  366  NVEE----AAF-TEDGLHINSDF-----------LDGLDKASAIAKMVEWLEAEGVGNEN  409

Query  539  VSYRLRDWLFSRQRYWGEPFPIVYDEDGVAHLVPDSELPIALPDVPDYQPKTYAPDDANS  598
            V+YRLRDWLFSRQRYWGEP+PI+  EDG +  VP+SELP+ LP   D +P        ++
Sbjct  410  VTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SG  461

Query  599  EPEAPLSRNEDWVKVQLDLGDGVKTYYRDTNTMPNWAGSCWYYMRYLDPNDAEHMVDSDE  658
              E+PL+   DW+ V  +  DGVK   R+TNTMP+WAGS WYY+RY+DP+++E + D + 
Sbjct  462  TGESPLANVTDWLEVTRE--DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEEL  518

Query  659  YDYWMGTNRPGKEHVSGGVDLYVGGVEHAVLHLLYSRFWHKALYDLGYVDSAEPFHRLFN  718
               W+             VD+YVGG EHAVLHLLY+RFWHK LYDLG V + EPF++LFN
Sbjct  519  LKQWL------------PVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFN  566

Query  719  QGMIQAYAYTDERGQYVPADEVeeganngagePTFTWHGETVNREFGKMGKSLKNIVTPD  778
            QGMI + +Y D RG  V++D VE    +     T    GE +++  +KM+KSLKN+V PD
Sbjct  567  QGMILGTSYRDSRGALVATDKVEKRDGSFFHVET----GEELEQAPAKMSKSLKNVVNPD  622

Query  779  YMYENYGADTFRLYEMSMGPLSESRPWNTRNVVGGMRFLQRLWRNVVNEETGACVVTEDA  838
             + E+YGADT+R+YEM MGPL  S +W+   + G+ +FL+R+ R +   E        +A
Sbjct  623  DVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITE--ENSGA  680

Query  839  LDEKTLKLLNNTIVEVTVEMEAMRPNTAIAKLIVLNNHLTSLPHVPRAAVEPLVLMLSPI  898
            LD    K+ N+T+  VT +++ M+ NTAIA+L+V+ N       +       +V +++P+
Sbjct  681  LD----KVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPF  736

Query  899  APHICEEMWSKL-GHTKSIAHADWPVEDSRYVGADTVTAVVQIKGKVRAKLEVDPNIDAS  957
            APH+ EE+W  L +   SI+   WP  D   +  + V  VVQIKGKV+AKL V  ++   
Sbjct  737  APHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSRE  796

Query  958  ELEKLAL--EAVADRLGGKKPRKVIVKAPKIVSIV  990
            EL+ +AL  E V   ++GK   KVI  + K+V+IV
Sbjct  797  ELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIV  831


 Score =  138 bits (507),  Expect = 2e-33, Method: Compositional matrix adjust.
 Identities = 80/149 (54%), Positives = 107/149 (72%), Gaps = 12/149 (8%)

Query  32   IEQRWQKTWDEQGTFWAANVKGDLKDGEGRLACGRPSFFAMDMFPYPSGKGLHVGHPLGY  91
            IE +WQ  W ++ TF         K G +    ++P F+A+DMFPYPSG GLHVGHP GY
Sbjct  9    IEPKWQAFWADNHTF---------KTGTD---ASKPKFYALDMFPYPSGAGLHVGHPEGY  56

Query  92   LATDVVSRYHRMKGENVLHAMGYDAFGLPAEQYAVQTGQHPRITTEANIANMRRQLHRMG  151
             ATD++SR+ R +G+NVLH+MG DAFGLPAEQYA++TG++P   T  NIAN +RQ++ +G
Sbjct  57   TATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALG  116

Query  152  LSFDDRRSFATIDTNYVRWTQWIFSKLYD  180
            +S+D  R   T D NY +WTQWIF+KLY+
Sbjct  117  FSYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1719) leuS in NC_014644


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  477 bits (1799),  Expect = 1e-135, Method: Compositional matrix adjust.
 Identities = 336/755 (45%), Positives = 481/755 (64%), Gaps = 74/755 (9%)

Query  239  IAYISKSPVNWCPGLGTVLANEEVTAEGKSERGNFPVFQRNLRQWSMRITAYAHRLVEDL  298
            +AY +  PVNW   LGT +ANEEV ++G SERG +PV ++ +RQW ++ITAYA+RL+EDL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  299  DTIDWPEKVKLMQRNWIGESHGASVHFEVECADGETRDLEVYTTRPDTLFGTTFAVVSVD  358
            + +DWPE +K MQRNWIG S GA+V F V  +D   +D+ V+TTRPDTLFG+T+AV++ +
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD---KDFTVFTTRPDTLFGATYAVLAPE  264

Query  359  HPILEHVPEAWEASVPESWKGGYASLKEGLAEYQAQARAKTAKDRTEDAGAKTGLFTGLY  418
            H++++ +                +   E++A+Y+ QA  K+   RT+ A  KTG+ TG Y
Sbjct  265  HALVDAITT--------------SDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSY  310

Query  419  AINPVTGAKLPLFVADYVLMGYGTGAIMAVPGGDQRDYDFAKAFGLSVIYTVKPLPDSVE  478
            AINPV G  +P+ +ADYVL +YGTGAIMAVP+ D+RD +FAK F L +I    P+ ++  
Sbjct  311  AINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDII----PVLEG-G  365

Query  479  KLEDYDGKAPFVSHDGIVINSSVEHTYKLGDALSINGLRVDEAIKKVTTWLEAAGVGVGK  538
            ++E+    A+F ++DG+ INS             ++GL    AI K+  WLEA GVG  +
Sbjct  366  NVEE----AAF-TEDGLHINSDF-----------LDGLDKASAIAKMVEWLEAEGVGNEN  409

Query  539  VSYRLRDWLFSRQRYWGEPFPIVYDEDGVAHLVPDSELPIALPDVPDYQPKTYAPDDANS  598
            V+YRLRDWLFSRQRYWGEP+PI+  EDG +  VP+SELP+ LP   D +P        ++
Sbjct  410  VTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SG  461

Query  599  EPEAPLSRNEDWVKVQLDLGDGVKTYYRDTNTMPNWAGSCWYYMRYLDPNDAEHMVDSDE  658
              E+PL+   DW+ V  +  DGVK   R+TNTMP+WAGS WYY+RY+DP+++E + D + 
Sbjct  462  TGESPLANVTDWLEVTRE--DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEEL  518

Query  659  YDYWMGTNRPGKEHVSGGVDLYVGGVEHAVLHLLYSRFWHKALYDLGYVDSAEPFHRLFN  718
               W+             VD+YVGG EHAVLHLLY+RFWHK LYDLG V + EPF++LFN
Sbjct  519  LKQWL------------PVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFN  566

Query  719  QGMIQAYAYTDERGQYVPADeveeganngvgePTFTWHGETVNREFGKMGKSLKNIVTPD  778
            QGMI + +Y D RG  V++D VE    +     T    GE +++  +KM+KSLKN+V PD
Sbjct  567  QGMILGTSYRDSRGALVATDKVEKRDGSFFHVET----GEELEQAPAKMSKSLKNVVNPD  622

Query  779  YMYENYGADTFRLYEMSMGPLSESRPWNTRNVVGGMRFLQRLWRNVVNEETGACVVTEDA  838
             + E+YGADT+R+YEM MGPL  S +W+   + G+ +FL+R+ R +   E        +A
Sbjct  623  DVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITE--ENSGA  680

Query  839  LDEKTLKLLNNTIVEVTVEMEAMRPNTAIAKLIVLNNHLTSLPHVPRAAVEPLVLMLSPI  898
            LD    K+ N+T+  VT +++ M+ NTAIA+L+V+ N       +       +V +++P+
Sbjct  681  LD----KVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPF  736

Query  899  APHICEEMWSKL-GHTKSIAHADWPVEDSRYVGADTVTAVVQIKGKVRAKLEVDPNIDAS  957
            APH+ EE+W  L +   SI+   WP  D   +  + V  VVQIKGKV+AKL V  ++   
Sbjct  737  APHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSRE  796

Query  958  ELEKLAL--EAVADRLGGKKPRKVIVKAPKIVSIV  990
            EL+ +AL  E V   ++GK   KVI  + K+V+IV
Sbjct  797  ELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIV  831


 Score =  138 bits (507),  Expect = 2e-33, Method: Compositional matrix adjust.
 Identities = 80/149 (54%), Positives = 107/149 (72%), Gaps = 12/149 (8%)

Query  32   IEQRWQKTWDEQGTFWAANVKGDLKDGEGRLACGRPSFFAMDMFPYPSGKGLHVGHPLGY  91
            IE +WQ  W ++ TF         K G +    ++P F+A+DMFPYPSG GLHVGHP GY
Sbjct  9    IEPKWQAFWADNHTF---------KTGTD---ASKPKFYALDMFPYPSGAGLHVGHPEGY  56

Query  92   LATDVVSRYHRMKGENVLHAMGYDAFGLPAEQYAVQTGQHPRITTEANIANMRRQLHRMG  151
             ATD++SR+ R +G+NVLH+MG DAFGLPAEQYA++TG++P   T  NIAN +RQ++ +G
Sbjct  57   TATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALG  116

Query  152  LSFDDRRSFATIDTNYVRWTQWIFSKLYD  180
            +S+D  R   T D NY +WTQWIF+KLY+
Sbjct  117  FSYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1720) leuS in NC_015434


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  477 bits (1798),  Expect = 2e-135, Method: Compositional matrix adjust.
 Identities = 342/736 (47%), Positives = 490/736 (67%), Gaps = 55/736 (7%)

Query  224  DHRLAYVSQAPVNWCPGLGTVLANEEVTADGRSERGNFPVFKRNLKQWMMRITAYGdrll  283
            +  LAY ++ PVNW   LGT +ANEEV +DG SERG +PV ++ ++QWM++ITAY++RLL
Sbjct  145  EKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLL  204

Query  284  ddldkldWPEPIKLMQRNWIGRSTGAHIDFPTATAP--IRVFTTRPDTVFGATYMVLAPE  341
            +DL+ +DWPE+IK MQRNWIG+STGA++ F    +   + VFTTRPDT+FGATY VLAPE
Sbjct  205  EDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPE  264

Query  342  HELVDALVPGAWPEGTRDAWTGGHASPRaaveayrkaaaaKTDVERQADTKEKTGVFTGA  401
            H LVDA+  +  +E+  D               Y++ A+ K+D+ R   +KEKTGV TG+
Sbjct  265  HALVDAITTSDQAEAVAD---------------YKRQASLKSDLARTDLAKEKTGVWTGS  309

Query  402  YATNPVTGGQIPIFIADYVLAGYGTGAIMAVPAQDERDWDFAEVFELPIVRTVAPPEGFD  461
            YA NPV G ++P+ IADYVLA+YGTGAIMAVPA+DERDW+FA  F+L I+  +   +  +
Sbjct  310  YAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNV-E  368

Query  462  GKAYTGDGPAINSAAPDRGLDLNGLGVADAKARIIAWLEETGNGQGATTYRLRDWLFSRQ  521
              A+T DG  INS        L+GL+ A A A+++ WLE  G G+   TYRLRDWLFSRQ
Sbjct  369  EAAFTEDGLHINSDF------LDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQ  422

Query  522  RYWGEPFPIVYDADGTAIAlpeemlpvelpevDDFSPRTFDPSDADSDPETPLSRRRDWV  581
            RYWGEP+PI+   DGT+ A+PE  LP+ LP   D+ P         +  E+PL+   DW+
Sbjct  423  RYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTDWL  474

Query  582  EVELDLGDGPKRYTRETNVMPQWAGSCWYELRYLDPTNEGRFVDADNERYWMGPRSEGDC  641
            EV  + G   +R   ETN MPQWAGS WY LRY+DP N  ++ D +  + W+        
Sbjct  475  EVTREDGVKGRR---ETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLP-------  524

Query  642  GGVDLYVGGAEHAVLHLLYARFWHKVLYDLGHVSSFEPFRKLFNQGYIQAYAYTDARGAY  701
              VD+YVGGAEHAVLHLLYARFWHKVLYDLG V++ EPF+KLFNQG I + +Y D+RGA 
Sbjct  525  --VDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGAL  582

Query  702  VPAEEVVERDGGFYLGDV--QVNREYGKMGKSLKNVVTPDEMCAAYGADTFRVYEMSMGP  759
            V+++ V  RDG+F+  +   ++++  +KM+KSLKNVV PD++   YGADT+RVYEM MGP
Sbjct  583  VATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGP  642

Query  760  LEVSRPWETRAVVGSYRFLQRVWRAIVDEQTGASRVVDTPADEATRRLLHKVIDGVRGDM  819
            L+ S +W   ++ GS +FL+RV R I      +++ +      A  ++ +  + +V  ++
Sbjct  643  LDASIAWSEEGLEGSRKFLDRVYRLI------TTKEITEENSGALDKVYNETVKAVTEQV  696

Query  820  EAIRFNTAIAKLIELTNGVTRLPATPREVAEPLVLMLAPVAPHIAEELWRRL-GHDTSLT  878
            + ++FNTAIA+L+ + N+  +      + A  +V ++AP APH++EELW+ L + + S++
Sbjct  697  DQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESIS  756

Query  879  YADFPVADPALLVAESVTYPVQVNGKVRGRIEVPADATEESVReq--aleavaavlaGKD  936
            Y   P  D + LV + V   VQ++GKV++++ V+ D + E ++E   A E V A +AGKD
Sbjct  757  YVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKD  816

Query  937  PRKVIVIPGRMVSVVL  952
              KVI +P ++V++V+
Sbjct  817  IIKVIAVPNKLVNIVI  832


 Score =  133 bits (489),  Expect = 5e-32, Method: Compositional matrix adjust.
 Identities = 73/149 (49%), Positives = 102/149 (69%), Gaps = 11/149 (7%)

Query  30   IERRWQDVWERDGTFHAPNPSGPLADPGHPRSGAEKLYVLDMFPYPSGAGLHVGHPLGYI  89
            IE +WQ  W  + TF +       +D++ P     K+Y LDMFPYPSGAGLHVGHP GY 
Sbjct  9    IEPKWQAFWADNHTFKTG------TDASKP-----KFYALDMFPYPSGAGLHVGHPEGYT  57

Query  90   GTDCFARYQRMAGRNVLHAMGFDAFGLPAEQYAVQTGTHPRTTTEANIERYREQLRRLGL  149
            +TD ++R++R  G+NVLH+MG DAFGLPAEQYA++TG +P   T  NI  ++ Q+  LG+
Sbjct  58   ATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGF  117

Query  150  AHDQRRSVATIDTDFYRWTQWIFLQIFNS  178
            + D  R V T D ++Y+WTQWIF ++++ 
Sbjct  118  SYDWDREVNTTDPNYYKWTQWIFTKLYEK  146

1721) leuS in NC_020133


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  477 bits (1799),  Expect = 2e-135, Method: Compositional matrix adjust.
 Identities = 337/742 (46%), Positives = 505/742 (69%), Gaps = 56/742 (7%)

Query  264   DHRLVYRADSMVNWCPGLGTVLANEEVTSDGRSDRGNFPVFRKRLRQWMMRITAYSdrll  323
             +  L Y A+  VNW   LGT +ANEEV +DG S+RG +PV RK +RQWM++ITAY++RLL
Sbjct  145   EKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLL  204

Query  324   ddldvldwpdQVKTMQRNWIGRSTGASALFTATRSNGETVGLEVFTTRPDTLFGATYLVL  383
             +DL+ +DWP+ +K MQRNWIG+STGA+  F    ++ +   + VFTTRPDTLFGATY VL
Sbjct  205   EDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKD---FTVFTTRPDTLFGATYAVL  261

Query  384   APEHDLVDDLVGAGWPAGVDPLWTGGGatpaeavaayrraiaaKSDLERQE-SKEKTGVF  442
             APEH LVD +  ++ + +V                  +R  + KSDL R + +KEKTGV 
Sbjct  262   APEHALVDAITTSDQAEAVADY---------------KRQASLKSDLARTDLAKEKTGVW  306

Query  443   LGSHAINPATGQPVPIFIADYVLAGYGTGAIMAVPGHDQRDWDFARALGLPVVEVIAGGD  502
              GS AINP  G+ +P+ IADYVLA+YGTGAIMAVP+HD+RDW+FA+ + L ++ V+ GG+
Sbjct  307   TGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGN  366

Query  503   ISQAAYTGDGVLVNSGFLDGMSVGEAKQAITARLESDGHGQARIEFKLRDWLFARQRYWG  562
             + +AA+T DG+ +NS+FLDG+  + A   +  +LE++G G+  + ++LRDWLF+RQRYWG
Sbjct  367   VEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWG  426

Query  563   EPFPIVYDADGRPHALDESALPVELPDVPDYSPVLFDPDDANSEPSPPLGKATEWVHVEL  622
             EP+PI+   DG + A+ ES LP+ LP   D  P        ++   +PL++ T+W++V  
Sbjct  427   EPIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTDWLEVTR  478

Query  623   DLGDGLKPYSRDTNVMPQWAGSSWYELRYTDPHNADRFCAKENETYWMGPRPAEHGPDDP  682
             +  DG+K   R+TN MPQWAGSSWY LRY DPHN++++   E    W+            
Sbjct  479   E--DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWL------------  523

Query  683   GGVDLYVGGAEHAVLHLLYARFWHKVLYDLGHVSSREPYRKLINQGYIQAFAYTDARGSY  742
               VD+YVGGAEHAVLHLLYARFWHKVLYDLG V+++EP++KL+NQG I + +Y D+RG+ 
Sbjct  524   -PVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGAL  582

Query  743   VPAEEVIVRDGGFVYPGADGEIEVFQEFGKIGKSLKNSISPDEICDDYGADTLRVYEMSM  802
             V+++ V  RDG+F    ++ E+E  Q  +K++KSLKN ++PD++ ++YGADTLRVYEM M
Sbjct  583   VATDKVEKRDGSFFHVETGEELE--QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFM  640

Query  803   GPIEASRPWATKDVIGAYRFLQRVWRLVIDENTGEILVADTPAELDTDTLRALHRAIAGV  862
             GP++AS +W+  ++ G+ +FL+RV RL+   +  E    + ++ LD    +  + ++ +V
Sbjct  641   GPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITE----ENSGALD----KVYNETVKAV  692

Query  863   AEDYAALRNNTAVAKLIEYTNFLTKRHRDAVPRAAIEPLVLMVAPLAPHLAEELWQRLGH  922
             +E+   ++ NTA+A+L+ + N   K ++  +       +V ++AP+APHL+EELWQ L  
Sbjct  693   TEQVDQMKFNTAIAQLMVFVNAANKEDK--LFSDYAKGFVQLIAPFAPHLGEELWQALTA  750

Query  923   TT-SLAHGPFPAADPAYLIDDTVEYPVQVNGKVRGRvvvaadadddavkaaaladqkvqa  981
             +  S++  P P+ D + L+++ VE  VQ++GKV++++VVA D   + ++  ALA++KVQA
Sbjct  751   SGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQA  810

Query  982   FLAGASPRKVIVVAGRLVNLVV  1003
              +AG    KVI V+ +LVN+V+
Sbjct  811   EIAGKDIIKVIAVPNKLVNIVI  832


 Score =  132 bits (485),  Expect = 1e-31, Method: Compositional matrix adjust.
 Identities = 73/150 (49%), Positives = 103/150 (69%), Gaps = 11/150 (7%)

Query  68   AGVERTWQQNWARLGTFNVPNPVGSLAPSDGSPVPEDKLFVQDMFPYPSGEGLHVGHPLG  127
            +++E  WQ  WA   TF+            G+  +  K++  DMFPYPSG GLHVGHP G
Sbjct  7    TAIEPKWQAFWADNHTFKT-----------GTDASKPKFYALDMFPYPSGAGLHVGHPEG  55

Query  128  YIATDVFARYHRMKGRNVLHALGFDAFGLPAEQYAVQTGTHPRTRTEANVVNFRRQLGRL  187
            Y ATD+++R+ R +G+NVLH++G DAFGLPAEQYA++TG +P   T  N+ NF+RQ+  L
Sbjct  56   YTATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINAL  115

Query  188  GLGHDSRRSFSTTDVEFYKWTQWIFLQIYN  217
            G++ D  R  +TTD ++YKWTQWIF ++Y+
Sbjct  116  GFSYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1722) MDS_4091 in NC_015410


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  477 bits (1797),  Expect = 2e-135, Method: Compositional matrix adjust.
 Identities = 363/886 (41%), Positives = 550/886 (63%), Gaps = 76/886 (8%)

Query  5    YSPREIEAAAQSHWDAQKSFVVSEQPGKDTFYCLSMFPYPSGK-LHMGHVRNYTIGDVIA  63
            Y    IE+  Q+ W  + +F  + +++K  FY L MFPYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMQGKNVLQPMGWDAFGMPAENAAMKNQVAPAKWTYENIAYMKSQLKSLGLAIDWTR  123
            R++R QG NVL+PMGWDAFG+PAE+ AM     PA  T ENIA  K Q+++LG++ DW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVTTCKPDYYRWEQWLFTRLFEKGVIYRKNGTVNWDPVDQTVLANEQVI-DGRGWRSGAL  182
            EV T  P+YY+W QW+FT+L+EKG+ Y  +  VNW     T +ANE+V+ DG + R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  IEKREIPMYYFKITAYAeellssldeldGWPEQVKTMQRNWIGKSFGADIVFDYDVASIG  242
            + ++ +    +KITAYA E L    E  +WPE +K MQRNWIGKS GA++ F       +
Sbjct  184  VVRKPMRQWMLKITAYA-ERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFK----VKD  238

Query  243  IDGQLKVYSTRPDTLMGATYVAVAAEHPLAQRAAESNPAIAAFIAECKAGSVAEADMA--  300
             D ++ V++TRPDTL GATY  +A+EH+L +  + S+ A A  +A+ K  +   +D+A  
Sbjct  239  TDKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEA--VADYKRQASLKSDLART  296

Query  301  --TMEKKGLATSQFVIHPLTGDKLPVFVANYVLWGYGEGAVMAVPAHDERDFEFANKYDL  358
              + EK G+ T+ + I+P+ G  +PV +A+YVL +YG GA+MAVPAHDERD EFA++++L
Sbjct  297  DLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNL  356

Query  359  PIKQVYTGDGKEYDASTWQDWYGDKAGLTTINSGKYDGLDFSAAFDAIVGDLEASEHGAR  418
             I  V  G+  E  A T         GL  INS+  DGLD ++A+  +V  LEA   G  
Sbjct  357  DIIPVLEGGNVEEAAFT-------EDGL-HINSDFLDGLDKASAIAKMVEWLEAEGVGNE  408

Query  419  KTQFRLRDWGISRQRYWGCPIPIIHCDSCGDVPVPEDQlpvvlpedvvpdGAG---SPLA  475
            +  +RLRDW +SRQRYWG PIPIIH +     +VPE +LP+VLP       +G   SPLA
Sbjct  409  NVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLA  468

Query  476  KMPEFYECNCPKCGAPAKRETDTMDTFVESSWYFARYASPNYDKGMVDPAAANHWLPVDQ  535
            ++ +  E      G  ++RET+TM     SSWY+ RY  P+    + D    ++WLPVD 
Sbjct  469  NVTDWLEVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDI  527

Query  536  YIGGIEHAILHLLYARFFHKLMRDEGLVSSNEPFKNLLTQGMVVAETYYRTLENGGKDWF  595
            Y+GG EHA+LHLLYARF HK++ D G+V+++EPF++L+ QGM+++ +Y            
Sbjct  528  YVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY------------  575

Query  596  NPADVEVERDAKAKVIGAKL--KSDG--LPVEIG-----GTEKMSKSKNNGVDPQDMIDA  646
                    RD+++ ++++    K DG  + VE G     +  KMSKS +N V+P+D+++ 
Sbjct  576  --------RDSRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQ  627

Query  647  YGADTCRLFMMFASPPDQSCEWSDAGVEGANRFLRRVWRLAHGHVNAGLPGKLDVASLND  706
            YGADT R++ MF +P D S  WS+ G+EG+ +FL RV RL             +++  ++
Sbjct  628  YGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTK---------EIT--EE  676

Query  707  EQKAVRRAIHLAIKQASNDIGQHHKFNTAVAQVMTLMNVLEKAATA-TEQDRALVQEGLE  765
            +  A+ +  + ++K  ++++ ++ KFNTA+AQ+M ++N  +K     ++  +++VQ    
Sbjct  677  NSGALDKVYNETVKAVTEQV-DQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQ----  731

Query  766  IVTLLLAPITPHISHELWQRLGHADAVID-AQWPQVDESALVQDSLTLVVQVNGKLRGQI  824
                L+AP++PH+++ELWQ L  ++  I    WP  DES LV++ + +VVQ++GK+++++
Sbjct  732  ----LIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKL  787

Query  825  EVPasasreeveaaaranenvLRFTEGLSIRKVIVVPGKLVNIVAN  870
             V+   SREE++  A ANE+V     G  I KVI VP KLVNIV +
Sbjct  788  VVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

1723) leuS in NC_010572


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  476 bits (1794),  Expect = 3e-135, Method: Compositional matrix adjust.
 Identities = 357/741 (49%), Positives = 495/741 (67%), Gaps = 62/741 (8%)

Query  220  LAYASDAPVNWSPGLGTVLANEEVTADGRSERGNFPVFKAKLRQWNMRITAYADRLLNDL  279
            LAY ++ PVNW   LGT +ANEEV +DG SERG +PV +  +RQW ++ITAYA+RLL+DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  280  DGLDWPEAIKLQQRNWIGRSEGARVEFPV-DTAGGITVFTTRQDTLFGATYMVLAPEHDM  338
            + +DWPE+IK  QRNWIG+S GA V F V DT  ++TVFTTR DTLFGATY VLAPEH +
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  339  VERIIPAAWPEGTHPVWTGGHASPAEAVTAYRKQAAAKSDVERQAEAKDKTGVFTGAYAT  398
            V+ I                 +  AEAV+ Y++QA+ KSD+ R   AK+KTGV TG+YA 
Sbjct  268  VDAITT---------------SDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAI  312

Query  399  NPVSGEKVPVFIADYVLMGYGTGAIMAVPAHdardfafarafELPMRCVVQPSDDRGTDP  458
            NPV+G  +PV IADYVL +YGTGAIMAVPAHD RD  FA+ F+L +  V++ ++      
Sbjct  313  NPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVE----  368

Query  459  ATWDDAFSSYDAKLVNSANDEISLDGLGVVEAKARITEWLKEHGVGEGTVNFRLRDWLFS  518
               + AF+  D+  +NS      LDGL+   A A++ EWL  +GVG+  V +RLRDWLFS
Sbjct  369  ---EAAFTE-DGLHINSD----FLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  519  RQRYWGEPFPIVYDEDGIAHplpesmlplelpeveDYSPRTFDPEDATAQPETPLSRNAD  578
            RQRYWGEP+PI+  EDG + ++PES LPL LP   D  P        ++  E+PL+  +D
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTD  472

Query  579  WVNVTLDLGDGAGPRKYRRETNTMPNWAGSCWYELRYLDPNNDRQLVDPSIEQYWMGPRE  638
            W++VT + G  +     RRETNTMP+WAGS WY LRY+DP+N  +L D  + + W+    
Sbjct  473  WLEVTREDGVKG-----RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWL----  523

Query  639  GQPTGGVDLYVGGAEHAVLHLLYARFWSKVLHDLGHISSAEPFHKLYNQGMIQAFVYRDS  698
                  VD+YVGGAEHAVLHLLYARFW KVL DLG +++ EPF+KL+NQGMI +  YRDS
Sbjct  524  -----PVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDS  578

Query  699  RGIAVPAAEVEERDGAFYH--AGEKVSRVLGKMGKSLKNAVTPDEICAEYGADTLRLYEM  756
            RG  V++  VE RDG+F+H  +GE + +  +KM+KSLKN V PD++  +YGADTLR+YEM
Sbjct  579  RGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEM  638

Query  757  AMGPLDVSRPWDTRAVVGQYRLLQRLWRNVVDEATGEVTVVDTEPDEDTL-RALHKAIDG  815
             MGPLD S +W   ++ G  ++L+R+ R +            TE + ++L +  + ++ +
Sbjct  639  FMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEI-------TEENSGALDKVYNETVKA  691

Query  816  VGQDMAGMRFNTAIAKVTELNNHLTKAGGPLSRSVAERLVLLIAPLAPHIAEELWRRL-G  874
            V +++  M+FNTAIA++  + N   K  + L    A  +V LIAP+APH++EELW+ L +
Sbjct  692  VTEQVDQMKFNTAIAQLMVFVNAANKE-DKLFSDYAKGFVQLIAPFAPHLGEELWQALTA  750

Query  875  HADSVVHQDFPVADPAYVVDETVTCVVQIKGKVRARLEISPAITdeelealaladeavva  934
             ++S+     P  D + +V++ V  VVQIKGKV+A+L ++  ++ EEL+ +ALA+E V A
Sbjct  751  SGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQA  810

Query  935  alggaGIRKVIVRAPKLVNIV  955
             ++G +I KVI  + KLVNIV
Sbjct  811  EIAGKDIIKVIAVPNKLVNIV  831


 Score =  133 bits (487),  Expect = 7e-32, Method: Compositional matrix adjust.
 Identities = 74/150 (50%), Positives = 101/150 (68%), Gaps = 10/150 (6%)

Query  22   ADIEARWQDFWDAEGTYEAPNPTGDLAGDPELAARPKKFIMDMFPYPSGAGLHVGHPLGY  81
            + IE++WQ FW  + T+ +             A++PK + +DMFPYPSGAGLHVGHP GY
Sbjct  7    TAIEPKWQAFWADNHTFKTGTD----------ASKPKFYALDMFPYPSGAGLHVGHPEGY  56

Query  82   IATDVYARHQRMTGHNVLHTLGFDAFGLPAEQYAVQTGTHPRVSTEANMENMKVQLRRLG  141
             ATD+ +R +R  GHNVLH +G DAFGLPAEQYA++TG +P   T  N+ N K Q+  LG
Sbjct  57   TATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALG  116

Query  142  LGHDNRRSFATIDSEYYKWTQWIFLQIFNS  171
            ++ D  R   T D++YYKWTQWIF ++++ 
Sbjct  117  FSYDWDREVNTTDPNYYKWTQWIFTKLYEK  146

1724) Alfi_1697 in NC_018011


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  476 bits (1795),  Expect = 3e-135, Method: Compositional matrix adjust.
 Identities = 319/726 (44%), Positives = 471/726 (65%), Gaps = 52/726 (7%)

Query  204  LAFRADTMVNWCAKLGTVLANDEV-HDGLSVRGGYPVEQKRMKQWLLRVTAYAQRMLDGL  262
            LA+ A+  VNW   LGT +AN+EV  DG S RGGYPV +K M+QW+L++TAYA+R+L++L
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  263  DKLAWSDSLKEIQRNWIGRSEGAQVFFDIKDSDRKLEIFTTRPDTIFGVTFMVIAPEHEW  322
            + + W++S+K++QRNWIG+S GA+V F +KD+D+ + +FTTRPDT+FG T+ V+APEH  
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  323  VDSLTTPENRAAVEEYICQAKKRSERERIAETKRVSGVATGSYAVNPFTGKAIPIYISDY  382
            VD++TT+++  AV +Y  QA  +S+  R   +K  +GV TGSYA+NP  GK +P+ I+DY
Sbjct  268  VDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAINPVNGKEMPVWIADY  327

Query  383  VLAGYGTGAIMAVPAHDSRDYAFARHFGLEIVPVVEGGDISQESYDAKSGKVINSDFLNG  442
            VLA+YGTGAIMAVPAHD RD  FA++F L+I+PV+EGG++ + ++ +  G  INSDFL+G
Sbjct  328  VLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEAAF-TEDGLHINSDFLDG  386

Query  443  KDVKEAIGLMFDEIERRGLGRKRINYRLRDAIFSRQRYWGEPFPIYY-KNDIACPLAEDK  501
             D   AI+ M + +E  G+G   + YRLRD +FSRQRYWGEP+PI    ++ + +++E  
Sbjct  387  LDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESE  446

Query  502  LPLELPPVADFGPTEQGEPPLARVKEW------ATPEGWPYELSTMPGFAGSSAYYLRYM  555
            LPL LP   D+ P+  GE+PLA V +W          G+  E +TMP  AGSS YYLRY+
Sbjct  447  LPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVKGRR-ETNTMPQWAGSSWYYLRYI  505

Query  556  DPHNDQALVGREADEYWRSVDLYVGGIEHATGHLMYSRFWNMFLYDLGVVCEEEPFRKLV  615
            DPHN + L + E    W +VD+YVGG EHA  HL+Y+RFW+  LYDLGVV   EPF+KL 
Sbjct  506  DPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLF  565

Query  616  NQGMIQGRSNFVYRIVGTNKFVSLGLKEQYRTQALYVDVNIVRNDILDIDAFRAWMPEYK  675
            NQGMI G S   YR  +   +V+ + K + R  +++   ++   + L+  +         
Sbjct  566  NQGMILGTS---YR-DSRGALVATD-KVEKRDGSFF---HVETGEELEQAP---------  608

Query  676  DAEFILEDGKYVCGWAIEKMSKSFYNVVNPDYIVENYGADTLRMYEMFLGPLEQSKPWDT  735
                              KMSKS+ NVVNPD +VE+YGADTLR+YEMF+GPL+ S +W  
Sbjct  609  -----------------AKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSE  651

Query  736  NGIDGVYKFLRRFWRLFYDRDGRLIVTDEKADEKELRTLHKTIKKVSEDIENFSFNTSVS  795
            +G++G  KFL R  RL+  ++    +T+E+++  + +  + T+K V+E++++  FNT+++
Sbjct  652  EGLEGSRKFLDRVYRLITTKE----ITEENSGALD-KVYNETVKAVTEQVDQMKFNTAIA  706

Query  796  AFMICLNELGECNK--REIIEPLTVLLAPFAPHIAEELWAALGHTT-SVCTADYPVYDEK  852
             +M+ +N     +K   +    +  L+APFAPH++EELW AL  +  S+     P YDE 
Sbjct  707  QLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDES  766

Query  853  HLAQSAFEYPVSINGKLRFKKEYATSLTPAQMQTDVVTLPEAQKWLEGKTPKKVIVVPGK  912
             L ++  E  V I+GK++ K   A  L+  ++Q   ++    Q  + GK   KVI VP K
Sbjct  767  KLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNK  826

Query  913  IINIVI  918
            ++NIVI
Sbjct  827  LVNIVI  832


 Score =  177 bits (656),  Expect = 3e-45, Method: Compositional matrix adjust.
 Identities = 91/141 (65%), Positives = 114/141 (81%), Gaps = 0/141 (0%)

Query  3    YNFKEIESKWQRRWQEDKTYKVETDPSRPKFYVLDMFPYPSGAGLHVGHPLGYIASDIYS  62
            Y+   IE+KWQ  W ++ T+K  TD+S+PKFY LDMFPYPSGAGLHVGHP GY A+DI S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRQKGFNVLHPMGYDAFGLPAEQYAIQTGQHPAVTTEQNIARYREQLDKIGFSFDWDR  122
            R+KR +G NVLHPMG DAFGLPAEQYA++TG++PA  T +NIA ++ Q++ +GFS+DWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVRTCDPGYYKWTQWAFLKMF  143
            EV T DP YYKWTQW F K++
Sbjct  124  EVNTTDPNYYKWTQWIFTKLY  144

1725) Sked_13250 in NC_013521


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  476 bits (1793),  Expect = 4e-135, Method: Compositional matrix adjust.
 Identities = 342/742 (47%), Positives = 486/742 (66%), Gaps = 56/742 (7%)

Query  235  DQRLAYVSNAPVNWCPGLGTVLANEEVTSEGRSERGNFPVFQRNLRQWNMRITAYADRLA  294
            ++ LAY ++ PVNW   LGT +ANEEV ++G SERG +PV ++ +RQW ++ITAYA+RL 
Sbjct  145  EKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLL  204

Query  295  DDLEDIDWPDKVKAMQRNWIGRSEGAHVTFDVTGGREPVTVFTTRPDTLFGATFMVVSPE  354
            +DLE++DWP+ +K MQRNWIG+S GA+VTF V +     TVFTTRPDTLFGAT+ V++PE
Sbjct  205  EDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPE  264

Query  355  HPLLDEVPAEWPDGTSAAWTGEHATPadavaayralaaaktaVERQADAGKKTGVFTGHL  414
            H+L+D +            T+++A +   VA Y+  A+ K+ + R   A  KTGV TG  
Sbjct  265  HALVDAIT-----------TSDQAEA---VADYKRQASLKSDLARTDLAKEKTGVWTGSY  310

Query  415  ATNPANGQLLPVFTADYVLMGYGTGAIMAVPGGDERDFAFAEAFGLPVVYTVATPEGFEG  474
            A NP NG+ +PV  ADYVL +YGTGAIMAVP+ DERD  FA  F L ++  V      E 
Sbjct  311  AINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDII-PVLEGGNVEE  369

Query  475  GAWTGDGAIVASSNDEVSLDGLSVTEAKSHMIEWLESKGTGSGTITYRLRDWLFSRQRYW  534
            +A T DG  + S      LDGL  + A + M+EWLE+ G G+  +TYRLRDWLFSRQRYW
Sbjct  370  AAFTEDGLHINSD----FLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYW  425

Query  535  GEPFPIVYGDDEQPIALTEAMLPVDLPDVPDYSPRTYapddadsspeppLGRNDDWVTVT  594
            GEP+PI+  +D  + A+ E+ LP+ LP   D  P          + E+PL+   DW+ VT
Sbjct  426  GEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSG--------TGESPLANVTDWLEVT  477

Query  595  LDLGDGPREYRRDTNTMPNWAGSCWYYLRYLDPHNDGPSATVPVDASLDSYWMGPNHNPT  654
             +  DG +  RR+TNTMP+WAGS WYYLRY+DPHN   +  ++ +  L   W+       
Sbjct  478  RE--DGVKG-RRETNTMPQWAGSSWYYLRYIDPHN---TEKLADEELLKQ-WL-------  523

Query  655  AGAAGGVDLYVGGVEHAVLHLLYARFWHKVLFDLGFVSSVEPFHKLFNQGYVQAYAFVDA  714
                  VD+YVGG EHAVLHLLYARFWHKVL+DLG V++ EPF+KLFNQG + + ++ D+
Sbjct  524  -----PVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDS  578

Query  715  RGAYVPADEVEEITAGDGSSMYVWNGESVTREYGKMGKSLKNVVTPDDMYEAYGADTFRV  774
            RGA V++D VE     DGS   V  GE + +  +KM+KSLKNVV PDD+ E YGADT+RV
Sbjct  579  RGALVATDKVEKR---DGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRV  635

Query  775  YEMSMGPLDVSRPWDTRAVVGSQRFLQRLWRNVVSEDTGELTVTDEPADLETLRHVHRAI  834
            YEM MGPLD S +W   ++ GS++FL+R+ R + + +  E    ++++ L+ +   + ++
Sbjct  636  YEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITE----ENSGALDKV--YNETV  689

Query  835  ADVRVEMENMRANTAIAKLITLNNHLTTLKSVPREAAEAIVLMTAPVAPHIAEELWARL-  893
              V  ++++M+ NTAIA+L+ + N       +  + A ++V + AP APH++EELW  L 
Sbjct  690  KAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALT  749

Query  894  GHDESLTYEPYPVADEQYLVQDSVTCVFQVQGKVRGRADVSPDTSeadlealaladPGVQ  953
            + +ES++Y P P  DE  LV++ V  V Q++GKV+++  V+ D S  +L+ +ALA+  VQ
Sbjct  750  ASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQ  809

Query  954  RALDGRDVMKVIVRAPKLVNIV  975
              + G+D++KVI  + KLVNIV
Sbjct  810  AEIAGKDIIKVIAVPNKLVNIV  831


 Score =  134 bits (493),  Expect = 2e-32, Method: Compositional matrix adjust.
 Identities = 77/151 (51%), Positives = 107/151 (71%), Gaps = 13/151 (8%)

Query  32   IELRWQERWAELGTFHAANPTGPLTDGKGRNADPSSPSFFVMDMFPFPSGAGLHVGHPLG  91
            IE +WQ  WA+  TF ++             +D+S P F+ +DMFP+PSGAGLHVGHP G
Sbjct  9    IEPKWQAFWADNHTFKTG-------------TDASKPKFYALDMFPYPSGAGLHVGHPEG  55

Query  92   YIATDVVGRFRRMSGDNVLHALGYDAFGLPAEQYAVQTGQHPRTTTEANIANMRRQLRRL  151
            Y ATD+++RF+R  G+NVLH++G DAFGLPAEQYA++TG++P   T  NIAN +RQ+  L
Sbjct  56   YTATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINAL  115

Query  152  GLAHDDRRSFATTDSEYVRWTQWIFLKMFNS  182
            G++ D  R   TTD++Y +WTQWIF K+++ 
Sbjct  116  GFSYDWDREVNTTDPNYYKWTQWIFTKLYEK  146

1726) AciPR4_3119 in NC_014963


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  476 bits (1793),  Expect = 4e-135, Method: Compositional matrix adjust.
 Identities = 351/874 (41%), Positives = 524/874 (60%), Gaps = 86/874 (9%)

Query  15   YTPSEIEPRWQAIWDVDASLYAAEDVTEGKPKYYVLEMLPYPSGQ-LHMGHVRNYSIGDA  73
            Y  + IEP+WQA+W  + ++ ++ D +  KPK+Y L+M+PYPSG  LH+GH   Y+  D 
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDAS--KPKFYALDMFPYPSGAGLHVGHPEGYTATDI  61

Query  74   LARYQWMRGFNVLHPMGWDSFGLPAENAAIKNNIPPREWTLGNIAEMRVQMRRMGLSYDW  133
            L+R+++ +G NVLHPMGWD+FGLPAE+ A+     P E T  NIA+ + Q+  +G+SYDW
Sbjct  62   LSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDW  121

Query  134  QREVTTCLPDYYKWNQWLFLKMYEKGLAYRKQSKVNWCPQCATVLANEQVVNGRCWRHED  193
            +REV T  P+YYKW QW+F K+YEKGLAY  +  VNW  + +T +ANE+V+ +    + +
Sbjct  122  DREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGG  181

Query  194  TVVEQRDLTQWFFRITKYADELLDGIDKLDGWPEKVRTMQRNWIGRSEGAEVIFHVTGTS  253
              V ++ + QW ++IT YA+ LL++++ +D WPE ++ MQRNWIG+S GA+V F V +T 
Sbjct  182  YPVVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  254  HTITVFTTRIDTIFGATSVQIAPEHPLAKEFGAADSALQQQIDAMIEQQKIAKEADSLG-  312
              +TVFTTR DT+FGAT   +APEH+L   + ++D     Q +A+ + ++ A     L+ 
Sbjct  241  KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSD-----QAEAVADYKRQASLKSDLAR  295

Query  313  ---AIEKQGVATGKFATNPFNGEQVPIWIGNYILADYGTGAIMSVPAHDERDFEFATKYG  369
               A EK GV TG +A NP NG ++P+WI++Y+LA YGTGAIM+VPAHDERD EFA ++ 
Sbjct  296  TDLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFN  355

Query  370  LEIKRVVAPNVDIDELALPYSGEDEAVLIDSGDWTGKNPLEAQGEMAAYAEANGFGKATV  429
            L+I  V+    +++E A+     ++++ I+S+   G +   A + M    EA+G G+  V
Sbjct  356  LDIIPVLEGG-NVEEAAFT----EDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENV  410

Query  430  TYRLKDWGVSRQRYWGTPIPIVYCDECGMqpvpleqlpvllpeKIDI--SGEGGSPLSRV  487
            TYRL+DW  SRQRYWG PIPI+  ++    +VP  +LP++LP   DI  SG G SPL+ V
Sbjct  411  TYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANV  470

Query  488  PEFVNVKCPTCGGEAKRETDTMDTFVDSSWYFYRYTDAKNDSAPFDSAKANYWFPIDQYI  547
             + ++V     G  ++RET+TM    +SSWY+ RY D+ N     D    + W+P+D Y+
Sbjct  471  TDWLEVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYV  529

Query  548  GGVEHAILHLIYSRYWTKVMRDLGLIENDEPATRLFTQGMVI------------------  589
            GG EHA+LHL+Y+R+W KV+ DLG++   EP  +LF QGM++                  
Sbjct  530  GGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVE  589

Query  590  ----------------KNGAKMSKSKGNIVSPDEMIAKYGADATRMYALFAAPPDRDLEW  633
                            +  AKMSKS  N+V+PD+++ +YGAD+ R+Y +F +P D  + W
Sbjct  590  KRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAW  649

Query  634  QEDGVAGISRFLARVYRLTTKYAPAIAAHEKREKKTHAGSFAALTPEGMKLLRKLHQTIA  693
             E+G+ G  +FL RVYRL T                       +T E    L K+ +   
Sbjct  650  SEEGLEGSRKFLDRVYRLITT--------------------KEITEENSGALDKVYNETV  689

Query  694  KITLDFSGRWHFNTCIASVMTLMNEISASEALMDGGAIAVETQTEVFRVLTlllapfapf  753
            K   +  ++  FNT IA +M ++N  +  + L  + A +       F          AP 
Sbjct  690  KAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPF----------APH  739

Query  754  lSQELWGLLGNEGPVFR-ASWPVADAELAKEDEIEIPVQINGKLASVVRvaadasedaik  812
            L++ELW  L   G  +   +WP  D     E+++EI VQI+GK+ + + VA D S + ++
Sbjct  740  LGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQ  799

Query  813  aaayadekvaaRLAGKTIVKVIYVPGKLVNIVVK  846
              A A+EKV A +AGK I+KVI VP KLVNIV+K
Sbjct  800  EVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

1727) Gobs_3367 in NC_013757


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  475 bits (1790),  Expect = 7e-135, Method: Compositional matrix adjust.
 Identities = 350/736 (48%), Positives = 502/736 (69%), Gaps = 56/736 (7%)

Query  232  LAYLHQAPVNWCPGLGTVLSNEEVTPDGRSERGNFPVFRRPLTQWMMRITAYAErlladl  291
            LAY  + PVNW   LGT ++NEEV PDG SERG +PV R+P+ QWM++ITAYAERLL DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  292  drldwsdsVKQMQRNWIGRSTGARIRFPV--GDRSIEVFTTRPDTLFGATYMVLAPEHPM  349
            + +DW++S+K+MQRNWIG+STGA + F V   D+ + VFTTRPDTLFGATY VLAPEH++
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  350  VETLTATAWPDGTDPRWTGGAATPAAAVRDYQRQASRRSELDRQNEAREKTGVWLGVTAV  409
            V+++T++                 A AV DY+RQAS +S+L R + A+EKTGVW G  A+
Sbjct  268  VDAITTSD---------------QAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAI  312

Query  410  NPVNGRELPVFIADYVLTGYGTGAIMAVPGEDNRDFEFAQVFGLPVVRTVQPPEDFDGGA  469
            NPVNG+E+PV IADYVL++YGTGAIMAVP++D+RD EFA+ F L ++  ++   + + +A
Sbjct  313  NPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE-GGNVEEAA  371

Query  470  YTGAGAMINSANDEISLNGLDKATAIATITDWLVQHGHGEATTTYKLRDWLFSRQRYWGE  529
            +T  G  INS      L+GLDKA+AIA + +WL  +G G+   TY+LRDWLFSRQRYWGE
Sbjct  372  FTEDGLHINSD----FLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGE  427

Query  530  PFPVVYDEDDLPVAVPESMLPVLLPEVDDYSPKTFddddadSAPEPPLSRVTDWTTVELD  589
            P+P++  ED+ + AVPES LP++LP   D  P         ++ E+PL+ VTDW  +E+ 
Sbjct  428  PIPIIHWEDGTSTAVPESELPLVLPVTKDIRPS--------GTGESPLANVTDW--LEVT  477

Query  590  LGEGLRKYRRETNTMPNWAGSCWYYLRYLDPSDDTQMVDPELERYWLGPREPgdvggvdl  649
              +G++  RRETNTMP+WAGS WYYLRY+DP +  ++ D EL + WL          VD+
Sbjct  478  REDGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLP---------VDI  527

Query  650  yvggMEHAVLHLLYARFWHKVLHDLGYVSSEEPFRRLVNQGYISAYAYTDERGFYVPAAE  709
            YVGG EHAVLHLLYARFWHKVL DLG V++ EPF++L NQG I + +Y D RG  V++  
Sbjct  528  YVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDK  587

Query  710  VEERDGQFLH--EGRPVNREYGKMGKSLKNMVTPDEMIGAYGADTLRVYEMSTGPLEQSR  767
            VE RDG F+H   G  +++  +KM+KSLKN+V PD+++  YGADTLRVYEM  GPL+ S 
Sbjct  588  VEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASI  647

Query  768  PWETKAVVGSQRLLQRIWRVVVDEETGAVRAADDIQPAEETLRALHRAIAGVRDGMSTLR  827
            +W   ++ GS+++L+R+ R++   E          + +    +  + ++ +V + +  ++
Sbjct  648  AWSEEGLEGSRKFLDRVYRLITTKEITE-------ENSGALDKVYNETVKAVTEQVDQMK  700

Query  828  FNISIARITELTNHLTQAYGADSAVPRSvaeplvllvaplapHIAEELWARL-GHGESLA  886
            FN +IA++  + N   +    +  +    A  +V L+AP+APH++EELW  L + GES++
Sbjct  701  FNTAIAQLMVFVNAANK----EDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESIS  756

Query  887  WHPFPVADERWLVEDTVQVAVQVNGKVRAQVTVPadadaaaleaaaraddkvaaHLDGKT  946
              P P  DE  LVE+ V++ VQ++GKV+A++ V+ D     L+  A A++KV A++ GK 
Sbjct  757  YVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKD  816

Query  947  VRRVVAVPGRLVNFVL  962
            + +V+AVP +LVN+V+
Sbjct  817  IIKVIAVPNKLVNIVI  832


 Score =  128 bits (470),  Expect = 2e-30, Method: Compositional matrix adjust.
 Identities = 80/149 (54%), Positives = 96/149 (65%), Gaps = 11/149 (7%)

Query  30   IELAWQDRWAAEGTFHTPNPVGRLSEGFERVADRPKAFVMDMFPYPSGAGLHVGHPLGYL  89
            IE  WQ  WA + TF T              A +PK + +DMFPYPSGAGLHVGHP GY 
Sbjct  9    IEPKWQAFWADNHTFKTGTD-----------ASKPKFYALDMFPYPSGAGLHVGHPEGYT  57

Query  90   GTDATSRFRRMDGANVLHPMGYDAFGLPAEQYAVQTGQHPRITTEANIAAIKGQLRRLGV  149
            +TD  SRF+R +G NVLHPMG DAFGLPAEQYA++TG++P   T  NIA +K Q+  LG 
Sbjct  58   ATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGF  117

Query  150  DHDERRTFATIDPGYYKWTQWIFLQIFGS  178
              D  R   T DP YYKWTQWIF +++  
Sbjct  118  SYDWDREVNTTDPNYYKWTQWIFTKLYEK  146

1728) Isova_2002 in NC_015588


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  475 bits (1789),  Expect = 8e-135, Method: Compositional matrix adjust.
 Identities = 347/751 (47%), Positives = 482/751 (65%), Gaps = 68/751 (9%)

Query  237  LAYVDESPVNWCPGLGTVLANEEVTADGRSERGNFPVFQRSLRQWKMRITAYADRLTDDL  296
            LAY  E PVNW   LGT +ANEEV +DG SERG +PV ++++RQW ++ITAYA+RL +DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  297  ELIDWPDKVKAMQRNWIGRSTGATIRFDVVGTSdddaagaggQLEVFTTRPDTLFGATFM  356
            E +DWP+ +K MQRNWIG+STGA + F V +T          ++ VFTTRPDTLFGAT+ 
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD--------KDFTVFTTRPDTLFGATYA  259

Query  357  VVAPEHPLLDEVPHAWPDGTRGSWTGGHRTPaeavaayraqaaaktaVERQADAGKKTGV  416
            V+APEH+L+D +  +                AEAVA Y+ QA+ K+ + R   A  KTGV
Sbjct  260  VLAPEHALVDAITTS--------------DQAEAVADYKRQASLKSDLARTDLAKEKTGV  305

Query  417  FTGHLAVNPVNGETIPVFTADYVLMGYGTGAIMAVPGGDERDFAFAEAYDLPVVHTVepe  476
             TG  A+NPVNG  +PV  ADYVL +YGTGAIMAVP+ DERD  FA  ++L ++  +   
Sbjct  306  WTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL---  362

Query  477  ggfpegfTGAYAGEGRTINSSNDEVSLDGLGVAEAKERIIAWLSERGVGESTTTYRLRDW  536
                +   +A++ +G  INS      LDGL+ A A  +++ WL   GVG+   TYRLRDW
Sbjct  363  -EGGNVEEAAFTEDGLHINSD----FLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDW  417

Query  537  LFSRQRYWGEPFPIV-WDEQDRPHAIPTELLPVDLPDVPDYAPRTFDPDDAQSSPEAPLG  595
            LFSRQRYWGEP+PI+ W++ + + A+P   LP+ LP   D  P         ++ E+PL+
Sbjct  418  LFSRQRYWGEPIPIIHWED-GTSTAVPESELPLVLPVTKDIRPS--------GTGESPLA  468

Query  596  RNTDWVEVTLDLGDGPKRYRRDTNTMPNWAGSCWYYLRYLDPTDSTNGDRVVDPELEKYW  655
              TDW+EVT +  DG K  RR+TNTMP+WAGS WYYLRY+DP ++   +++ D EL K W
Sbjct  469  NVTDWLEVTRE--DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNT---EKLADEELLKQW  522

Query  656  MGPRHNPTSGPAGGVDLYVGGVEHAVLHLLYARFWHKVLYDLGYVSSLEPFGTLFNQGYI  715
            +             VD+YVGG EHAVLHLLYARFWHKVLYDLG V++ EPF  LFNQG I
Sbjct  523  L------------PVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMI  570

Query  716  QAYAFTDSRGAYVPAAEVTEEPGPDGEVVYRWNGEVVQREYGKMGKSLKNVVTPDEMYEQ  775
             + ++ DSRGA V++  V    G+  +V     GE +++  +KM+KSLKNVV PD++ EQ
Sbjct  571  LGTSYRDSRGALVATDKVEKRDGSFFHVE---TGEELEQAPAKMSKSLKNVVNPDDVVEQ  627

Query  776  YGADTFRVYEMSMGPLDLSRPWETRAVVGSQRFLQRLWRNvvdeetgevtvtddepdAAT  835
            YGADT+RVYEM MGPLD S +W   ++ GS++FL+R+ R              +E  +A 
Sbjct  628  YGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYR------LITTKEITEENSGAL  681

Query  836  LRALHRAIADVRTEMEHMRPNTAIAKLITYNNHLTGLDRVPRAAVEPLVLMVAPVAPHIA  895
             +  + ++  V  ++++M+ NTAIA+L+ + N     D++       +V ++AP APH++
Sbjct  682  DKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLG  741

Query  896  EELWERL-GHETSLAREPFPVADERYLVEDTVTCVVQVKGKVRGRLEVAPSISEEDLTAA  954
            EELW+ L +   S++  P P  DE  LVE+ V  VVQ+KGKV+++L VA  +S E+L   
Sbjct  742  EELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEV  801

Query  955  ALAEPNVVRAIGGAEVRKVIVRAPKLVNIVV  985
            ALA+ +V   I+G ++ KVI  + KLVNIV+
Sbjct  802  ALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832


 Score =  125 bits (458),  Expect = 1e-29, Method: Compositional matrix adjust.
 Identities = 70/151 (47%), Positives = 101/151 (67%), Gaps = 13/151 (8%)

Query  24   IEKRWQDRWEERGTFYAANPVGGLTDGEGRTAEGLGAPFFVMDMFPYPSGAGLHVGHPLG  83
            IE +WQ  W +  TF                +++  + F+ +DMFPYPSGAGLHVGHP G
Sbjct  9    IEPKWQAFWADNHTF-------------KTGTDASKPKFYALDMFPYPSGAGLHVGHPEG  55

Query  84   YIATDVVGRFRMMCGDNVLHALGYDAFGLPAEQYAVQTGQHPRVTTEQNIATMRRQLRRM  143
            Y ATD+++RF+   G+NVLH++G DAFGLPAEQYA++TG++P   T +NIA  +RQ+  +
Sbjct  56   YTATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINAL  115

Query  144  GLGHDPRRTFATIDPEYVRWTQWIFLQIFDS  174
            G++ D  R   T DP+Y +WTQWIF ++++ 
Sbjct  116  GFSYDWDREVNTTDPNYYKWTQWIFTKLYEK  146

1729) SFUL_2132 in NC_021177


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  474 bits (1786),  Expect = 1e-134, Method: Compositional matrix adjust.
 Identities = 350/740 (48%), Positives = 488/740 (66%), Gaps = 60/740 (8%)

Query  229  LAYASDAPVNWSPGLGTVLANEEVTADGRSERGNFPVFKAKLRQWNMRITSYADRLLNDL  288
            LAY ++ PVNW   LGT +ANEEV +DG SERG +PV +  +RQW ++IT+YA+RLL+DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  289  DGLDWPDAIKLQQRNWIGRSEGARVEFPV-DSAGGITVFTTRQDTLFGATYMVLAPEHEL  347
            + +DWP++IK  QRNWIG+S GA V F V D+  ++TVFTTR DTLFGATY VLAPEH L
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  348  VERIIPAAWPEGTHPVWTGGHTNPAEAVTAYRKQAAAKSDIERQAEAKDKTGVFTGAYAT  407
            V+ I                 ++ AEAV+ Y++QA+ KSD+ R   AK+KTGV TG+YA 
Sbjct  268  VDAITT---------------SDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAI  312

Query  408  NPVSGEKVPVFIADYVLMGYGTGAIMAVPAHdardfafarafELPMRCVVQPSDDRGTDP  467
            NPV+G  +PV IADYVL +YGTGAIMAVPAHD RD  FA+ F+L +  V++ ++      
Sbjct  313  NPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEE---  369

Query  468  STWDDAFGSYDAKLVNSANDEISLDGLGVVEAKAKITEWLQEHGVGEGTVNFRLRDWLFS  527
                   +++    ++  +D   LDGL+   A AK+ EWL+ +GVG+  V +RLRDWLFS
Sbjct  370  -------AAFTEDGLHINSD--FLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  528  RQRYWGEPFPIVYDEEGIAHplpesmlplelpeveDYSPRTFDPEDADTQPETPLSRNAD  587
            RQRYWGEP+PI+  E+G + ++PES LPL LP   D  P            E+PL+  +D
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTD  472

Query  588  WVNVTLDLGDGAGPRKYRRETNTMPNWAGSCWYELRYLDPNNDRQLVDPEIEQYWMGPRE  647
            W++VT + G  +     RRETNTMP+WAGS WY LRY+DP+N  +L D E+ + W+    
Sbjct  473  WLEVTREDGVKG-----RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWL----  523

Query  648  GQPTGGVDLYVGGAEHAVLHLLYARFWSKVLHDLGHISSAEPFHKLYNQGMIQAFVYRDS  707
                  VD+YVGGAEHAVLHLLYARFW KVL DLG +++ EPF+KL+NQGMI +  YRDS
Sbjct  524  -----PVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDS  578

Query  708  RGIAVPAAEVEERDGAFYY--EGEKVSRVLGKMGKSLKNAVTPDEICAEYGADTLRLYEM  765
            RG  V++  VE RDG+F+    GE + +  +KM+KSLKN V PD++  +YGADTLR+YEM
Sbjct  579  RGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEM  638

Query  766  AMGPLDVSRPWDTRAVVGQYRLLQRLWRNvvdeetgevtvvdtepgedALRALHKAIDGV  825
             MGPLD S +W   ++ G  ++L+R+ R +   E  E      +      +  + ++ +V
Sbjct  639  FMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALD------KVYNETVKAV  692

Query  826  GQDLEGMRFNTAIAKITELNNHLTKAGGPLSRSVAERLVLLIAPLAPHVAEELWRRL-GH  884
             ++++ M+FNTAIA++  + N   K  + L    A  +V LIAP+APH++EELW+ L + 
Sbjct  693  TEQVDQMKFNTAIAQLMVFVNAANKE-DKLFSDYAKGFVQLIAPFAPHLGEELWQALTAS  751

Query  885  TESVVHQDFPVADPAYVVDETVTCVVQIKGKVRARLEISPSITDEELETlaladpavvaa  944
             ES+     P  D + +V++ V  VVQIKGKV+A+L ++  ++ EEL+ +ALA+  V A 
Sbjct  752  GESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAE  811

Query  945  lggagIRKVIVRAPKLVNIV  964
            ++G +I KVI  + KLVNIV
Sbjct  812  IAGKDIIKVIAVPNKLVNIV  831


 Score =  134 bits (490),  Expect = 4e-32, Method: Compositional matrix adjust.
 Identities = 74/150 (50%), Positives = 101/150 (68%), Gaps = 10/150 (6%)

Query  31   ADIEARWQDFWDAEGTYEAPNPTGDLAGDPELAAKPKKFIMDMFPYPSGAGLHVGHPLGY  90
            + IE++WQ FW  + T+ +             A+KPK + +DMFPYPSGAGLHVGHP GY
Sbjct  7    TAIEPKWQAFWADNHTFKTGTD----------ASKPKFYALDMFPYPSGAGLHVGHPEGY  56

Query  91   IATDVYARHQRMTGHNVLHTLGFDAFGLPAEQYAVQTGTHPRASTEANMENMKVQLRRLG  150
             ATD+ +R +R  GHNVLH +G DAFGLPAEQYA++TG +P   T  N+ N K Q+  LG
Sbjct  57   TATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALG  116

Query  151  LGHDNRRSFATIEAEYYKWTQWIFLQIFNS  180
            ++ D  R   T +++YYKWTQWIF ++++ 
Sbjct  117  FSYDWDREVNTTDPNYYKWTQWIFTKLYEK  146

1730) leuS in NC_011896


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  473 bits (1783),  Expect = 2e-134, Method: Compositional matrix adjust.
 Identities = 336/744 (46%), Positives = 497/744 (67%), Gaps = 62/744 (8%)

Query  232  LVYRADSMVNWCPGLGTVLANEEVTADGRSDRGNFPVFRKRLRQWMMRITAYAdrllddl  291
            L Y A+  VNW   LGT +ANEEV +DG S+RG +PV RK +RQWM++ITAYA+RLL+DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  292  dlldWPEQVKTMQRNWIGRSSGATVLFSAILSRSDAATTEVDVEVFTTRPDTMFGVTYLV  351
            + +DWPE +K MQRNWIG+S+GA V F           T+ D  VFTTRPDT+FG TY V
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKV-------KDTDKDFTVFTTRPDTLFGATYAV  260

Query  352  LAPEHNLVDELVATVWPDRTDPRWtygaatpgaavaayrraivaKSDLDRQE-SKEKTGV  410
            LAPEH LVD + ++   D++++            VA Y+R    KSDL R + +KEKTGV
Sbjct  261  LAPEHALVDAITTS---DQAEA------------VADYKRQASLKSDLARTDLAKEKTGV  305

Query  411  FLGRYATNPATGKPVPIFVADYVLVGYGTGAVMAVPGHDPRDWDFAHKFHLPIVEVIAGS  470
              G YA NP  GK +P+ +ADYVL +YGTGA+MAVP+HD RDW+FA +F+L I+ V+ G+
Sbjct  306  WTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGG  365

Query  471  DISEAAYVGDGVLVNSGYLDGMDVATAQEAITARLESEGRGHARIEFKLRDWLFARQRYW  530
            ++ EAA+  DG+ +NS++LDG+D A+A   +  +LE+EG G+  + ++LRDWLF+RQRYW
Sbjct  366  NVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYW  425

Query  531  GEPFPIIYDSDGRPHALDEAALPVELPDVPYYSPVLFdpddadsepsppLAKATEWVHVE  590
            GEP+PII   DG + A+ E+ LP+ LP      P         +   +PLA+ T+W++V 
Sbjct  426  GEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTDWLEVT  477

Query  591  LDLGDGLKPYSRDTNVMPQWAGSSWYELRYTDPHNSERLCAKENEAYWMGPRPTEHGIDD  650
             +  DG+K   R+TN MPQWAGSSWY LRY DPHN+E+L   E    W+           
Sbjct  478  RE--DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWL-----------  523

Query  651  PGGVDLYVGGAEHAVLHLLYARFWHKVLYDLGHVSSREPYRRLINQGYIQAFAYTDAHGS  710
               VD+YVGGAEHAVLHLLYARFWHKVLYDLG V+++EP+++L+NQG I + +Y D++G+
Sbjct  524  --PVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGA  581

Query  711  YVPANQVFQRGDGFFCPGPDGEIEVFQEFGKIGKSLKNSVSPDEICDEYGADTLRVYEMS  770
             V++++V +R+++FF    + E+E  Q  +K++KSLKN V+PD++ ++YGADTLRVYEM 
Sbjct  582  LVATDKVEKRDGSFFHVETGEELE--QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMF  639

Query  771  MGPLEASRPWATKDVVGAYRFLQRVWRLVVDERTGETRVVDTAGELDTYTLRTLHRTIAG  830
            MGPL+AS +W+  ++ G+ +FL+RV RL+      E    + +G LD    +  + T+ +
Sbjct  640  MGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITE----ENSGALD----KVYNETVKA  691

Query  831  VSQDYAALRNNTATAKLIEYTNHLTKEHR--GSVPRvaveplvlmlaplaphlaeelwlR  888
            V+++   ++ NTA A+L+ + N   KE++  +  ++  V+ +    + L+ +L + L   
Sbjct  692  VTEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALT--  749

Query  889  LGHTTSLANGPFPQADPAYLVDDTVEYPVQVNGKIRGRIVVAADADYDTLKTVALADDKV  948
             +   S++  P P  D + LV++ VE  VQ++GK+++++VVA D   + L+ VALA++KV
Sbjct  750  -ASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKV  808

Query  949  QQFLAGATPRKVIVVAGRLISLVI  972
            Q  +AG    KVI V+ +L+++VI
Sbjct  809  QAEIAGKDIIKVIAVPNKLVNIVI  832


 Score =  134 bits (491),  Expect = 3e-32, Method: Compositional matrix adjust.
 Identities = 76/148 (52%), Positives = 102/148 (69%), Gaps = 11/148 (7%)

Query  35   IESTWQDNWARLQTFNVPNPVGSLAPPDGSVVPADKLFVQDMFPYPSGDGLHVGHPLGYI  94
            IE+ WQ  WA  +TF+            G+  +  K++  DMFPYPSG GLHVGHP GY 
Sbjct  9    IEPKWQAFWADNHTFKT-----------GTDASKPKFYALDMFPYPSGAGLHVGHPEGYT  57

Query  95   ATDVYARYFRMTGHNVLHAMGFDAFGLPAEQYAMQTGTHPRILTEANVVNFRHQLGRLGL  154
            ATD+ +R+ R  GHNVLH+MG DAFGLPAEQYAM+TG +P  +T  N+ NF++Q+  LG+
Sbjct  58   ATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGF  117

Query  155  GHDSRRTFSTTDVEFYKWTQWIFLQIYN  182
            + D  R  +TTD ++YKWTQWIF ++Y+
Sbjct  118  SYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1731) leuS in NC_002677


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  473 bits (1783),  Expect = 2e-134, Method: Compositional matrix adjust.
 Identities = 336/744 (46%), Positives = 497/744 (67%), Gaps = 62/744 (8%)

Query  232  LVYRADSMVNWCPGLGTVLANEEVTADGRSDRGNFPVFRKRLRQWMMRITAYAdrllddl  291
            L Y A+  VNW   LGT +ANEEV +DG S+RG +PV RK +RQWM++ITAYA+RLL+DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  292  dlldWPEQVKTMQRNWIGRSSGATVLFSAILSRSDAATTEVDVEVFTTRPDTMFGVTYLV  351
            + +DWPE +K MQRNWIG+S+GA V F           T+ D  VFTTRPDT+FG TY V
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKV-------KDTDKDFTVFTTRPDTLFGATYAV  260

Query  352  LAPEHNLVDELVATVWPDRTDPRWtygaatpgaavaayrraivaKSDLDRQE-SKEKTGV  410
            LAPEH LVD + ++   D++++            VA Y+R    KSDL R + +KEKTGV
Sbjct  261  LAPEHALVDAITTS---DQAEA------------VADYKRQASLKSDLARTDLAKEKTGV  305

Query  411  FLGRYATNPATGKPVPIFVADYVLVGYGTGAVMAVPGHDPRDWDFAHKFHLPIVEVIAGS  470
              G YA NP  GK +P+ +ADYVL +YGTGA+MAVP+HD RDW+FA +F+L I+ V+ G+
Sbjct  306  WTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGG  365

Query  471  DISEAAYVGDGVLVNSGYLDGMDVATAQEAITARLESEGRGHARIEFKLRDWLFARQRYW  530
            ++ EAA+  DG+ +NS++LDG+D A+A   +  +LE+EG G+  + ++LRDWLF+RQRYW
Sbjct  366  NVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYW  425

Query  531  GEPFPIIYDSDGRPHALDEAALPVELPDVPYYSPVLFdpddadsepsppLAKATEWVHVE  590
            GEP+PII   DG + A+ E+ LP+ LP      P         +   +PLA+ T+W++V 
Sbjct  426  GEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTDWLEVT  477

Query  591  LDLGDGLKPYSRDTNVMPQWAGSSWYELRYTDPHNSERLCAKENEAYWMGPRPTEHGIDD  650
             +  DG+K   R+TN MPQWAGSSWY LRY DPHN+E+L   E    W+           
Sbjct  478  RE--DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWL-----------  523

Query  651  PGGVDLYVGGAEHAVLHLLYARFWHKVLYDLGHVSSREPYRRLINQGYIQAFAYTDAHGS  710
               VD+YVGGAEHAVLHLLYARFWHKVLYDLG V+++EP+++L+NQG I + +Y D++G+
Sbjct  524  --PVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGA  581

Query  711  YVPANQVFQRGDGFFCPGPDGEIEVFQEFGKIGKSLKNSVSPDEICDEYGADTLRVYEMS  770
             V++++V +R+++FF    + E+E  Q  +K++KSLKN V+PD++ ++YGADTLRVYEM 
Sbjct  582  LVATDKVEKRDGSFFHVETGEELE--QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMF  639

Query  771  MGPLEASRPWATKDVVGAYRFLQRVWRLVVDERTGETRVVDTAGELDTYTLRTLHRTIAG  830
            MGPL+AS +W+  ++ G+ +FL+RV RL+      E    + +G LD    +  + T+ +
Sbjct  640  MGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITE----ENSGALD----KVYNETVKA  691

Query  831  VSQDYAALRNNTATAKLIEYTNHLTKEHR--GSVPRvaveplvlmlaplaphlaeelwlR  888
            V+++   ++ NTA A+L+ + N   KE++  +  ++  V+ +    + L+ +L + L   
Sbjct  692  VTEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALT--  749

Query  889  LGHTTSLANGPFPQADPAYLVDDTVEYPVQVNGKIRGRIVVAADADYDTLKTVALADDKV  948
             +   S++  P P  D + LV++ VE  VQ++GK+++++VVA D   + L+ VALA++KV
Sbjct  750  -ASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKV  808

Query  949  QQFLAGATPRKVIVVAGRLISLVI  972
            Q  +AG    KVI V+ +L+++VI
Sbjct  809  QAEIAGKDIIKVIAVPNKLVNIVI  832


 Score =  134 bits (491),  Expect = 3e-32, Method: Compositional matrix adjust.
 Identities = 76/148 (52%), Positives = 102/148 (69%), Gaps = 11/148 (7%)

Query  35   IESTWQDNWARLQTFNVPNPVGSLAPPDGSVVPADKLFVQDMFPYPSGDGLHVGHPLGYI  94
            IE+ WQ  WA  +TF+            G+  +  K++  DMFPYPSG GLHVGHP GY 
Sbjct  9    IEPKWQAFWADNHTFKT-----------GTDASKPKFYALDMFPYPSGAGLHVGHPEGYT  57

Query  95   ATDVYARYFRMTGHNVLHAMGFDAFGLPAEQYAMQTGTHPRILTEANVVNFRHQLGRLGL  154
            ATD+ +R+ R  GHNVLH+MG DAFGLPAEQYAM+TG +P  +T  N+ NF++Q+  LG+
Sbjct  58   ATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGF  117

Query  155  GHDSRRTFSTTDVEFYKWTQWIFLQIYN  182
            + D  R  +TTD ++YKWTQWIF ++Y+
Sbjct  118  SYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1732) FraEuI1c_0670 in NC_014666


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  473 bits (1781),  Expect = 4e-134, Method: Compositional matrix adjust.
 Identities = 340/768 (45%), Positives = 487/768 (64%), Gaps = 86/768 (11%)

Query  232  LAYLAEGLVNWCPGLGTVLANEEVTADGRSDIGNYPVFRRPLRQWTLRITAYAERLMADL  291
            LAY AE  VNW   LGT +ANEEV +DG S+ G YPV R+P+RQW L+ITAYAERL+ DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  292  DLVDWPDSIKQMQRNWIGPSDGAHVTFAAFTGDPDGPPRPALALDVYTTRPDTLPGATFM  351
            + VDWP+SIK+MQRNWIG S GA+VTF     D D        + V+TTRPDTL GAT+ 
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKD--------FTVFTTRPDTLFGATYA  259

Query  352  VLAPEHPLVDALTASEWPTGTPAEWTFNEGRPAGTSDADWTPaaavaaYQEFAGTRSDRQ  411
            VLAPEH+LVDA+T+S+              ++ + +D           Y+  A+ +SD  
Sbjct  260  VLAPEHALVDAITTSD--------------QAEAVAD-----------YKRQASLKSDLA  294

Query  412  RGE-EVDRTGVFTGAYARNPVTGKAIPIFLADYVLLGYGTGAVMAVPAHDQRDFSFAREF  470
            R +   ++TGV TG+YA NPV GK +P+ +ADYVL +YGTGA+MAVPAHD+RD  FA++F
Sbjct  295  RTDLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQF  354

Query  471  GLPTPPVLAPNDDFLAEHGLSSNDSVDVWPVAFSGEGEYLPAPPGAPVLTGLSKTDAVKA  530
             L   PVL   +    E++  ++D++++       ++++L          GL K+ A+  
Sbjct  355  NLDIIPVLEGGN---VEEAAFTEDGLHI-------NSDFL---------DGLDKASAIAK  395

Query  531  TVSWLEAAGTGRAARSYRLRDWLFSRQRYWGEPFPIVYDETGLPIAVPDDVLPVQLPEMT  590
             V WLEA G G    +YRLRDWLFSRQRYWGEP+PI+  E G + AVP+  LP+ LP   
Sbjct  396  MVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTK  455

Query  591  DFRPTPMAEDDTSDPVPPLARASDWTTVTLDLGDGPRQYRRETNTMPQWAGSCWYYLRYL  650
            D+RP+  +E       +PLA  +DW  VT +  DG +  RRETNTMPQWAGS WYYLRY+
Sbjct  456  DIRPSGTGE-------SPLANVTDWLEVTRE--DGVKG-RRETNTMPQWAGSSWYYLRYI  505

Query  651  DPTNAERFVDPEIERYWMPSvdgpdgdggvdlyvggvEHAVLHLLYARFWHKVLYDLGLV  710
            DP N+E++ D E+ + W+P           D+YVGG EHAVLHLLYARFWHKVLYDLG+V
Sbjct  506  DPHNTEKLADEELLKQWLPV----------DIYVGGAEHAVLHLLYARFWHKVLYDLGVV  555

Query  711  STREPFKRLFNQGYIQADAFLDARGMYVPAVEVTTEADGTLRYE-GEPVSRRSGKMGKSL  769
            +T+EPF++LFNQG I + ++ D+RG  V++  V    ++ ++ E GE + + ++KM+KSL
Sbjct  556  PTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSL  615

Query  770  KNSVTPDEMYDAYGADTLRVYEMAMGPLDADRPWRTDDIVGPHRFLQRLWRNLIDEETGQ  829
            KN V PD++ + YGADTLRVYEM MGPLDA  +W  +++ G+++FL+R+ R +   E  +
Sbjct  616  KNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITE  675

Query  830  PRVADADLDDEATRTLHRTILAVRADYAGMRFNTAVARLIELTNFVSKHHSSEAKRPPRA  889
               +  D      +  + T+ AV  +   M+FNTA+A+L+ + N  +K++     +    
Sbjct  676  ENSGALD------KVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKED-----KLFSD  724

Query  890  LAEAMVLMLAPLAPHITEELWTRLGHDGSLVR-EPFPVGDEALAAESTVTLPVQVNGKVR  948
             A + V ++AP+APH+ EELW  L   G  +   P P  DE+   E+ V + VQ++GKV+
Sbjct  725  YAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVK  784

Query  949  FTLSVPVGAGEDEVKAALTAHEDYAKHTDGKTVKRLIVVPGRIINIAI  996
              L V+ + + +E++    A+E    +  GK + ++I VP +++NI I
Sbjct  785  AKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832


 Score =  134 bits (490),  Expect = 4e-32, Method: Compositional matrix adjust.
 Identities = 77/149 (52%), Positives = 104/149 (70%), Gaps = 11/149 (7%)

Query  35   IESRWQSWWREHGTFASPNPIGPLSDGFDEVKGLDPFFVLDMFPYPSGAGLHVGHPLGYI  94
            IE++WQ+ W ++ TF +         G D  K    F+ LDMFPYPSGAGLHVGHP GY 
Sbjct  9    IEPKWQAFWADNHTFKT---------GTDASKP--KFYALDMFPYPSGAGLHVGHPEGYT  57

Query  95   GTDVYARYLRMTGRHVLHSFGYDAFGLPAEQYAINTGQHPRVTTEANIANMRRQLGRLGL  154
            +TD+ +R+ R  G++VLH+ G DAFGLPAEQYA++TG++P   T  NIAN +RQ+  LG+
Sbjct  58   ATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGF  117

Query  155  GHDTRREIATTDVTYYRWTQWIFKKIFDS  183
            + D  RE+ TTD  YY+WTQWIF K+++ 
Sbjct  118  SYDWDREVNTTDPNYYKWTQWIFTKLYEK  146

1733) SHJG_4065 in NC_017765


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  472 bits (1780),  Expect = 4e-134, Method: Compositional matrix adjust.
 Identities = 359/738 (49%), Positives = 492/738 (67%), Gaps = 59/738 (7%)

Query  225  LAYASDAPVNWCPGLGTVLANEEVTADGRSERGNFPVFKAKLRQWNMRITAYAdrlledl  284
            LAY ++ PVNW   LGT +ANEEV +DG SERG +PV +  +RQW ++ITAYA+RLLEDL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  285  eeldWPEAIKLQQRNWIGRSEGARVDFPI-DGER-ITVFTTRPDTLFGATYMVLAPEHPL  342
            EE+DWPE+IK  QRNWIG+S GA V F + D ++ +TVFTTRPDTLFGATY VLAPEH+L
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  343  VEKFTPEAWPEGTHEVWTGGHATPaeavaayraqaaSKSDVERQAEAKDKTGVFTGAFAT  402
            V+ +T    +E+  +               Y+ QA+ KSD+ R   AK+KTGV TG++A 
Sbjct  268  VDAITTSDQAEAVAD---------------YKRQASLKSDLARTDLAKEKTGVWTGSYAI  312

Query  403  NPVNGERVPVFIADYVLMGYGTGAIMAVPAHDSRDFAFARAFELPIRCVVEPTDGRGTDP  462
            NPVNG  +PV IADYVL +YGTGAIMAVPAHD RD  FA+ F+L I  V+E  +   +  
Sbjct  313  NPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEA--  370

Query  463  STWDDAFVSYDAKIVNSDSDDVRLNGLGVVEAKARITEWLEREGIGEGTVNFRLRDWLFS  522
                    ++    ++ +SD   L+GL+   A A++ EWLE EG+G+  V +RLRDWLFS
Sbjct  371  --------AFTEDGLHINSD--FLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  523  RQRYWGEPFPIVYDEDGIAHAlpesmlplelpeieDYSPRTFDPDDADTKPETPLSRNEE  582
            RQRYWGEP+PI+  EDG + A+PES LPL LP   D  P            E+PL+   +
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTD  472

Query  583  WVNVTLDLGDGPKKYRRETNTMPNWAGSCWYEFRYLDPHNDQKLVDPEIERYWMGPREGR  642
            W++VT +  DG K  RRETNTMP+WAGS WY +RY+DPHN +KL D E+ + W+      
Sbjct  473  WLEVTRE--DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLP-----  524

Query  643  PHGGVDLYVGGAEHAVLHLLYARFWSKVLYDLGHVSSAEPFHKLFNQGMIQAYVYRDSRG  702
                VD+YVGGAEHAVLHLLYARFW KVLYDLG V++ EPF+KLFNQGMI +  YRDSRG
Sbjct  525  ----VDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRG  580

Query  703  IAVPAAEVEERDGAYYY--QGQQVSRLLGKMGKSLKNAVTPDEIAAEYGADTLRLYEMAM  760
              V++  VE RDG+++    G+++ +  +KM+KSLKN V PD++  +YGADTLR+YEM M
Sbjct  581  ALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFM  640

Query  761  GPLDVSRPWDTRAVVGQFRLLQRLWRNIVDENTGEVTVTDAEADEETLRALHKAIDGVRQ  820
            GPLD S +W   ++ G  ++L+R+ R I   +  E      +      +  + ++ +V +
Sbjct  641  GPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALD------KVYNETVKAVTE  694

Query  821  DLEGLRFNTAIAKVTELNNHLTKAGAAVPRSVAEPLVLMVAPLAPHIAEELWRKL-GHTD  879
            +++ ++FNTAIA++  + N   K +   +   A  +V ++AP+APH++EELW+ L +  +
Sbjct  695  QVDQMKFNTAIAQLMVFVNAANKEDKLFS-DYAKGFVQLIAPFAPHLGEELWQALTASGE  753

Query  880  SVVHQDFPVADPAYvvdetvtcvvqvKGKVKARLEVPPTISEEELEKVALADEKVVAALD  939
            S+     P  D + +V++ V  VVQ+KGKVKA+L V+  +S EEL+ VALA+EKV A + 
Sbjct  754  SISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIA  813

Query  940  GAGIRKVIVRAPKLVNIV  957
            G +I KVI  + KLVNIV
Sbjct  814  GKDIIKVIAVPNKLVNIV  831


 Score =  136 bits (501),  Expect = 6e-33, Method: Compositional matrix adjust.
 Identities = 75/150 (50%), Positives = 101/150 (68%), Gaps = 10/150 (6%)

Query  26   AEIEARWQDFWDADGTYAAANPTGDLAGDPELVAKPKKFIMDMFPYPSGAGLHVGHPLGY  85
            + IE++WQ FW  + T+ ++  +          +KPK + +DMFPYPSGAGLHVGHP GY
Sbjct  7    TAIEPKWQAFWADNHTFKTGTDA----------SKPKFYALDMFPYPSGAGLHVGHPEGY  56

Query  86   IATDVYARFQRMTGHNVLHTLGFDAFGLPAEQHAVATGEHPRITTEAAINNMKSQLRRLG  145
             ATD+ +RF+R  GHNVLH +G DAFGLPAEQ A+ TG++P   T   I N K Q+  LG
Sbjct  57   TATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALG  116

Query  146  LGHDKRRSFATIDPEYYKWTQWIFLRIFNS  175
            ++ D  R   T DP+YYKWTQWIF ++++ 
Sbjct  117  FSYDWDREVNTTDPNYYKWTQWIFTKLYEK  146

1734) SHJGH_3830 in NC_020895


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  472 bits (1780),  Expect = 4e-134, Method: Compositional matrix adjust.
 Identities = 359/738 (49%), Positives = 492/738 (67%), Gaps = 59/738 (7%)

Query  225  LAYASDAPVNWCPGLGTVLANEEVTADGRSERGNFPVFKAKLRQWNMRITAYAdrlledl  284
            LAY ++ PVNW   LGT +ANEEV +DG SERG +PV +  +RQW ++ITAYA+RLLEDL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  285  eeldWPEAIKLQQRNWIGRSEGARVDFPI-DGER-ITVFTTRPDTLFGATYMVLAPEHPL  342
            EE+DWPE+IK  QRNWIG+S GA V F + D ++ +TVFTTRPDTLFGATY VLAPEH+L
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  343  VEKFTPEAWPEGTHEVWTGGHATPaeavaayraqaaSKSDVERQAEAKDKTGVFTGAFAT  402
            V+ +T    +E+  +               Y+ QA+ KSD+ R   AK+KTGV TG++A 
Sbjct  268  VDAITTSDQAEAVAD---------------YKRQASLKSDLARTDLAKEKTGVWTGSYAI  312

Query  403  NPVNGERVPVFIADYVLMGYGTGAIMAVPAHDSRDFAFARAFELPIRCVVEPTDGRGTDP  462
            NPVNG  +PV IADYVL +YGTGAIMAVPAHD RD  FA+ F+L I  V+E  +   +  
Sbjct  313  NPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEA--  370

Query  463  STWDDAFVSYDAKIVNSDSDDVRLNGLGVVEAKARITEWLEREGIGEGTVNFRLRDWLFS  522
                    ++    ++ +SD   L+GL+   A A++ EWLE EG+G+  V +RLRDWLFS
Sbjct  371  --------AFTEDGLHINSD--FLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  523  RQRYWGEPFPIVYDEDGIAHAlpesmlplelpeieDYSPRTFDPDDADTKPETPLSRNEE  582
            RQRYWGEP+PI+  EDG + A+PES LPL LP   D  P            E+PL+   +
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTD  472

Query  583  WVNVTLDLGDGPKKYRRETNTMPNWAGSCWYEFRYLDPHNDQKLVDPEIERYWMGPREGR  642
            W++VT +  DG K  RRETNTMP+WAGS WY +RY+DPHN +KL D E+ + W+      
Sbjct  473  WLEVTRE--DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLP-----  524

Query  643  PHGGVDLYVGGAEHAVLHLLYARFWSKVLYDLGHVSSAEPFHKLFNQGMIQAYVYRDSRG  702
                VD+YVGGAEHAVLHLLYARFW KVLYDLG V++ EPF+KLFNQGMI +  YRDSRG
Sbjct  525  ----VDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRG  580

Query  703  IAVPAAEVEERDGAYYY--QGQQVSRLLGKMGKSLKNAVTPDEIAAEYGADTLRLYEMAM  760
              V++  VE RDG+++    G+++ +  +KM+KSLKN V PD++  +YGADTLR+YEM M
Sbjct  581  ALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFM  640

Query  761  GPLDVSRPWDTRAVVGQFRLLQRLWRNIVDENTGEVTVTDAEADEETLRALHKAIDGVRQ  820
            GPLD S +W   ++ G  ++L+R+ R I   +  E      +      +  + ++ +V +
Sbjct  641  GPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALD------KVYNETVKAVTE  694

Query  821  DLEGLRFNTAIAKVTELNNHLTKAGAAVPRSVAEPLVLMVAPLAPHIAEELWRKL-GHTD  879
            +++ ++FNTAIA++  + N   K +   +   A  +V ++AP+APH++EELW+ L +  +
Sbjct  695  QVDQMKFNTAIAQLMVFVNAANKEDKLFS-DYAKGFVQLIAPFAPHLGEELWQALTASGE  753

Query  880  SVVHQDFPVADPAYvvdetvtcvvqvKGKVKARLEVPPTISEEELEKVALADEKVVAALD  939
            S+     P  D + +V++ V  VVQ+KGKVKA+L V+  +S EEL+ VALA+EKV A + 
Sbjct  754  SISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIA  813

Query  940  GAGIRKVIVRAPKLVNIV  957
            G +I KVI  + KLVNIV
Sbjct  814  GKDIIKVIAVPNKLVNIV  831


 Score =  136 bits (501),  Expect = 6e-33, Method: Compositional matrix adjust.
 Identities = 75/150 (50%), Positives = 101/150 (68%), Gaps = 10/150 (6%)

Query  26   AEIEARWQDFWDADGTYAAANPTGDLAGDPELVAKPKKFIMDMFPYPSGAGLHVGHPLGY  85
            + IE++WQ FW  + T+ ++  +          +KPK + +DMFPYPSGAGLHVGHP GY
Sbjct  7    TAIEPKWQAFWADNHTFKTGTDA----------SKPKFYALDMFPYPSGAGLHVGHPEGY  56

Query  86   IATDVYARFQRMTGHNVLHTLGFDAFGLPAEQHAVATGEHPRITTEAAINNMKSQLRRLG  145
             ATD+ +RF+R  GHNVLH +G DAFGLPAEQ A+ TG++P   T   I N K Q+  LG
Sbjct  57   TATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALG  116

Query  146  LGHDKRRSFATIDPEYYKWTQWIFLRIFNS  175
            ++ D  R   T DP+YYKWTQWIF ++++ 
Sbjct  117  FSYDWDREVNTTDPNYYKWTQWIFTKLYEK  146

1735) leuS in NC_014033


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  472 bits (1779),  Expect = 5e-134, Method: Compositional matrix adjust.
 Identities = 313/741 (43%), Positives = 465/741 (63%), Gaps = 60/741 (8%)

Query  204  IAYLAETMVNWCPALGTVLANDEVI-NGVSERGGYPVEQKKMRQWCLRVSAYAQRLLDGL  262
            +AY AE  VNW   LGT +AN+EV+ +G SERGGYPV +K MRQW L+++AYA+RLL++L
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  263  DTIDWTDSLKETQRNWIGRSEGTEVEFNVADSDKHFTIFTTRADTMFGVTFMVLAPESDL  322
            + +DW +S+K+ QRNWIG+S G++V F+V D+DK+FT+FTTR+DT+FG T+ VLAPE  L
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  323  VAELTTADQKAAVDEYLAYVKKRTERER-QMDHKVTGVFSGSYAINPFTDEKIPIWISEY  381
            V  +TT+DQ  AV +Y      +++  R ++    TGV +GSYAINP  +  +P+WI++Y
Sbjct  268  VDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAINPVNGKEMPVWIADY  327

Query  382  VLAGYGTGAIMAVPAHDSRDYAFAKHFNLPIIPLIEGADVSEESYDAKEGIVCNSSSAKF  441
            VLA+YGTGAIMAVPAHD RD  FAK+FNL IIP++EG++V E ++ + +G+  NS    F
Sbjct  328  VLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEAAF-TEDGLHINSD---F  383

Query  442  SLNGLTVKEAIAATKKYVTEQGLGRVKVNYRLRDAIFSRQRYWGEPFPVYY-KDDMPYMI  500
             L+GL    AIA     +  +G+G  +V YRLRD +FSRQRYWGEP+P+    D+ +  +
Sbjct  384  -LDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAV  442

Query  501  PKECLPLELPEIDEYKPTETGEPPLGRAKMWAWDTKTDKVVSKDEIDNKTVFPLELNTMP  560
            P   LPL LP   + +P+ TGE+PL+    W        V   D +  +     E NTMP
Sbjct  443  PESELPLVLPVTKDIRPSGTGESPLANVTDWL------EVTREDGVKGRR----ETNTMP  492

Query  561  GFAGSSAYYLRYMDPKNEQALVSKDADEYWRNVDLYVGGTEHATGHLIYSRFWNKFLFDS  620
              AGSS YYLRY+DP N + L   +    W  VD+YVGG+EHA  HL+Y+RFW+K L+D 
Sbjct  493  QWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDL  552

Query  621  GYSCEDEPFKKLVNQGMIQGRSNFVYRIEDEGADKGKFVSLNLRGNYKETTPIHVDVNIV  680
            G     EPF+KL NQGMI G S   YR       +G +V+ + + + ++ + +HV+    
Sbjct  553  GVVPTKEPFQKLFNQGMILGTS---YR-----DSRGALVATD-KVEKRDGSFFHVE----  599

Query  681  SADILDIEAFKAWRPDYNNAEFILEDGKYICGWAIEKMSKSMFNVVNPDMIVEKYGADTL  740
            +++ L+  +                           KMSKS+ NVVNPD +VE+YGADTL
Sbjct  600  TGEELEQAP--------------------------AKMSKSLKNVVNPDDVVEQYGADTL  633

Query  741  RLYEMFLGPVEQSKPWDTNGIDGCHRFLKKFWNLFQNGFDEGAATPENLKSV-HKLIKKV  799
            R+YEMF+GP++ S +W  +G++G ++FL +   L+    +     +  L  V +  +K V
Sbjct  634  RVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTK-EITEENSGALDKVYNETVKAV  692

Query  800  STDIETFSYNTSISAFMICVNELGQQKCKNKEMLKTLVILIAPFAPHMAEELWEMLGEQG  859
            + +++   +NT+I+ +M+ VN   ++     +  K +V LIAPFAPH++EELW+ L   G
Sbjct  693  TEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASG  752

Query  860  -SVCDSQWPKWEEKYLVESEAKLGVAFNGKTRFDMTFPADADNKTIEEAVLADERAQKYL  918
             S+    WP  +E  LVE++  + V ++GK +  +  + D     ++E  LA+E+ Q  +
Sbjct  753  ESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEI  812

Query  919  EGFQVAKVIIVPKRMVNIVLK  939
             G ++ KVI VP+++VNIV+K
Sbjct  813  AGKDIIKVIAVPNKLVNIVIK  833


 Score =  168 bits (620),  Expect = 2e-42, Method: Compositional matrix adjust.
 Identities = 83/141 (59%), Positives = 108/141 (77%), Gaps = 0/141 (0%)

Query  3    YNFRDIEQKWQKRWVENGTYRVVEDKNKKKFYVLNMFPYPSGAGLHVGHPLGYIASDIYA  62
            Y+   IE KWQ  W +N T++   D +K KFY L+MFPYPSGAGLHVGHP GY A+DI +
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRQQGYNVLNPMGYDAYGLPAEQYAIQTGQHPEKTTFENINRYRSQLDKIGFSFDWER  122
            R+KR QG NVL+PMG DA+GLPAEQYA++TG++P   T ENI  ++ Q++ +GFS+DW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVRTCDPIYYKWTQWAFQRMF  143
            EV T DP YYKWTQW F +++
Sbjct  124  EVNTTDPNYYKWTQWIFTKLY  144

1736) leuS in NC_010830


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  471 bits (1775),  Expect = 1e-133, Method: Compositional matrix adjust.
 Identities = 317/726 (44%), Positives = 471/726 (65%), Gaps = 49/726 (6%)

Query  206  LAFLEDTTVNWCPELGTVLANEEV-KDGLSERGGYPVIRKQMKQWSLRITAYTDRLLAGL  264
            LA+  +  VNW  ELGT +ANEEV  DG SERGGYPV+RK M+QW L+ITAY++RLL +L
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  265  EHLKWPLSTKEMQRNWIGRSIGAELNFTVIANGQEHTIPVFTTRPDTLFGVTYLALSPEH  324
            E++ WP S K+MQRNWIG+S GA++ F V  ++ +  + VFTTRPDTLFG TY  L+PEH
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKV--KDTDKDFTVFTTRPDTLFGATYAVLAPEH  265

Query  325  PLAKLISTGTQQAAIDTYITQATNRSERDRLADVNHVTGMFTGAYAIHPFTKQPLPIWIA  384
            +L   I+T+ Q  A+  Y  QA+ +S+  R    ++ TG+ TG+YAI+P   + +P+WIA
Sbjct  266  ALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAINPVNGKEMPVWIA  325

Query  385  DYVLAGYGTGAVMGVPAHDSRDYAFAQHFQLPIIQVVAGGDTAQSAYEAREGSLFNSQFL  444
            DYVLA+YGTGA+M+VPAHD RD  FA++F+L II V+ GG+  ++A+ + +G  +NS+FL
Sbjct  326  DYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEAAF-TEDGLHINSDFL  384

Query  445  NGLSIQEATKQAIQKLESLGIGKQKTTYRLRNAIFSRQRYWGEPIPIYY-KNNIPYPIpa  503
            +GL    A  + ++ LE+ G+G+++ TYRLR+ +FSRQRYWGEPIPI    +  + ++P 
Sbjct  385  DGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPE  444

Query  504  eelplelpslasFKPTPTGEPPLGHAPNW---KTKEGY--PIELSTMPGWAGSSWYFFRY  558
             ELPL LP    ++P+ TGE+PL++  +W      +G     E +TMP WAGSSWY++RY
Sbjct  445  SELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRY  504

Query  559  MDPNNEASFVGSTAQNYWQAVDLYLGGAEHATGHLLYARFWTQFLYDLGYVNIEEPFQEL  618
            +DP+N   + +    + W +VD+Y+GGAEHA  HLLYARFW + LYDLG V   EPFQ L
Sbjct  505  IDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKL  564

Query  619  IHQGMIQGKSSFVYRIKGTNQFVSYNLRHAYETTAMHVDIHLVKNNILDLERFKNWRPDL  678
            ++QGMI G S   YR                ++ +  V  + V +               
Sbjct  565  FNQGMILGTS---YR----------------DSRGALVATDKVEKR--------------  591

Query  679  QTATFVLENGQYICGSEVEKMSKSKYNTVNPDTVVEQYGADTLRLYTMFLGPIEQAKPWD  738
            + + F +E G+ +      KMSKS  N VNPD VVEQYGADTLR+Y MF+GP++ + +W 
Sbjct  592  DGSFFHVETGEEL-EQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWS  650

Query  739  MHGIEGVFRFLVKVWRLFYLEKGAIITNEVPTKEVQKAIHKAIKKVEEDIKRYAFNTAVS  798
             +G+EG  +FL +V RL+     +    E  +  ++K  + ++K V E++ +  FNTA++
Sbjct  651  EEGLEGSRKFLDRVYRLI----TTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIA  706

Query  799  NLMICVNELTALKCNNRAALTNLVLILAPFAPHLAEELWEIL-GHQHSIAQAPFPTYEEI  857
            +LM+ VN               +V ++APFAPHL+EELW+ L +  +SI+  P P+Y+E 
Sbjct  707  QLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDES  766

Query  858  YLQEETYEYPIAINGKVRAKINFPVDMPQGQIEEQVLTHESIQKWIQGQQIKRVIVISSK  917
             L E+  E  + I+GKV+AK+  + D+++ +++E  L++E +Q  I G++I +VI +++K
Sbjct  767  KLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNK  826

Query  918  MVNIVI  923
            +VNIVI
Sbjct  827  LVNIVI  832


 Score =  184 bits (682),  Expect = 3e-47, Method: Compositional matrix adjust.
 Identities = 89/145 (62%), Positives = 120/145 (83%), Gaps = 0/145 (0%)

Query  1    MSHYDFKAIEQKWQQYWKNNQIFRTTIEPSKPKYYILDMFPYPSGEGLHVGHPLGYIASD  60
            M+ YD  AIE KWQ +W +N+ F+T  ++SKPK+Y LDMFPYPSG GLHVGHP GY A+D
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   IVARYKRSKGYQVLHPMGFDAFGLPAEQFAIQTGQHPAITTAKNIGRYKQQLCQLGLSYD  120
            I++R+KR++G +VLHPMG DAFGLPAEQ+A++TG++PA  TA NI+ +K+Q+  LG+SYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WDRCISTCEPAYYKWTQWIFIQLFN  145
            WDR ++T +P YYKWTQWIF +L++
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYE  145

1737) Jden_1568 in NC_013174


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  470 bits (1773),  Expect = 2e-133, Method: Compositional matrix adjust.
 Identities = 340/741 (46%), Positives = 486/741 (66%), Gaps = 60/741 (8%)

Query  245  LAYVSEAPVNWCPGLGTVLANEEVTAEGRSERGNYPVFQRPMRQWNMRITAYsdrlisdl  304
            LAY +E PVNW   LGT +ANEEV ++G SERG YPV ++PMRQW ++ITAY++RL+ DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  305  dlidWPDKVKSMQRHWVGRSEGAHVTFAV--GQESLQVFTTRPDTLFGATFMVVAPEHPL  362
            + +DWP+ +K MQR+W+G+S GA+VTF V   +  + VFTTRPDTLFGAT+ V+APEH+L
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  363  VESAVPEQWPASTRDAWTGGYDNPRDAVRAYQQEAAAKTAVERQADAKSKTGVFTGIFAT  422
            V++                   +  +AV  Y+++A+ K+ + R   AK KTGV TG +A 
Sbjct  268  VDAITT---------------SDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAI  312

Query  423  NPVNGHEIPVFTADYVLMGYGTGAIMAVPGGddrdfafarafdLDVVYTVAPPEGFGEDR  482
            NPVNG E+PV  ADYVL +YGTGAIMAVP+ D+RD  FA+ F+LD++  +    G  E+ 
Sbjct  313  NPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE--GGNVEEA  370

Query  483  AWTGDGAVINSHNDEVSLDGMSVDDAKHTIIAWLEERGAGSGTVTYRLRDWLFSRQRYWG  542
            A T DG  INS+     LDG+    A   ++ WLE  G G+  VTYRLRDWLFSRQRYWG
Sbjct  371  AFTEDGLHINSD----FLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWG  426

Query  543  EPFPIVYDNDGRPVALPESMLPVALPDTPDFAPRTFEPDDANSEPEPPLGRNSDWVNVEL  602
            EP+PI+  +DG + A+PES LP+ LP T D+ P        ++  E+PL+  +DW++V  
Sbjct  427  EPIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTDWLEVTR  478

Query  603  DLGDGPRMYRRETNTMPNWAGSCWYYLRYIDPFNNSSDAEHVVSKELEQYWIGPHHNDVV  662
            +  DG +  RRETNTMP+WAGS WYYLRYIDP     ++E +   EL + W+        
Sbjct  479  E--DGVKG-RRETNTMPQWAGSSWYYLRYIDP----HNTEKLADEELLKQWL--------  523

Query  663  GAAGGVDLYVGGVEHAVLHLLYARFWHKVLFDLGHVSSPEPFHRLFNQGYIQAYAYTDER  722
                 VD+YVGG EHAVLHLLYARFWHKVL+DLG V++ EPF++LFNQG I + +Y D R
Sbjct  524  ----PVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSR  579

Query  723  GQYVPAAEVDEHVSENGDTTYTWQDQSVTREYGKMGKSLKNVVTPDDMYELYGADTFRVY  782
            G  V++  V+ + +   +      ++ + +  +KM+KSLKNVV PDD+ E YGADT+RVY
Sbjct  580  GALVATDKVEKRDGSFFHVE---TGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVY  636

Query  783  EMSMGPLDLSRPWETRAVVGAQRFLQRLWRNIIDEHtgditvtddtaatdtLKVLHRTIA  842
            EM MGPLD S +W   ++ G+++FL+R+ R I   +  +             KV + T+ 
Sbjct  637  EMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALD------KVYNETVK  690

Query  843  AVRDEMEGMRINTAIAKLIELNNHLTSLPAVPRHAAEALVIMTAPVAPHIAEELWHRL-G  901
            AV ++++ M++NTAIA+L+ + N       +  + A ++V + AP APH++EELW+ L +
Sbjct  691  AVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTA  750

Query  902  HDDSVVYQPFPTPDEAYLVDDTITAIFQVQGKVRGKADVPTSISEQDLTDAALANEGVVR  961
             ++S+ Y P P+ DE+ LV++ +  + Q++GKV++K  V+  +S ++L + ALANE V  
Sbjct  751  SGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQA  810

Query  962  SLDGRGIRKVIVRAPKLVNIV  982
             + G++I KVI  + KLVNIV
Sbjct  811  EIAGKDIIKVIAVPNKLVNIV  831


 Score =  128 bits (469),  Expect = 2e-30, Method: Compositional matrix adjust.
 Identities = 71/151 (48%), Positives = 104/151 (69%), Gaps = 13/151 (8%)

Query  33   IERTWQQRWEDEGTYHAADPLGGLTDGRGLHADPDSPSFFVMDMFPFPSGAGLHVGHPLG  92
            IE  WQ  W D+ T+ ++             +D+  P F+ +DMFP+PSGAGLHVGHP G
Sbjct  9    IEPKWQAFWADNHTFKTG-------------TDASKPKFYALDMFPYPSGAGLHVGHPEG  55

Query  93   YIATDAVARFRRMNGDNVLHALGFDAFGLPTELYAIQTGQHPRVATQNNIANMQRQLRRM  152
            Y ATD ++RF+R +G+NVLH++G DAFGLP+E YA++TG++P   T +NIAN +RQ+  +
Sbjct  56   YTATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINAL  115

Query  153  GLGHDSRRSFATTDTHYVRWTQWIFLQIFNS  183
            G++ D  R   TTD +Y +WTQWIF ++++ 
Sbjct  116  GFSYDWDREVNTTDPNYYKWTQWIFTKLYEK  146

1738) leuS in NC_013061


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  469 bits (1768),  Expect = 4e-133, Method: Compositional matrix adjust.
 Identities = 319/739 (44%), Positives = 463/739 (63%), Gaps = 61/739 (8%)

Query  205  LTYLKESTVNWCAALGTVLANDEV-KDGFSERGGHPVEQKKMMQWSMRISAYAERLLQGL  263
            L+Y  E  VNW   LGT +AN+EV  DG SERGG PV +K M QW ++I+AYAERLL++L
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  264  NTIDWPEPVKEMQRNWIGKSIGAAVKFKIEAAVSKALPAGVDAIEVFTTRVDTIFGVSYL  323
            + +DWPE++K+MQRNWIGKS GA V FK+  +           + VFTTR DT+FG +Y 
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDK--------DFTVFTTRPDTLFGATYA  259

Query  324  VLAPEHELVTALTTPGQLDAVNSYIAQTKKKSELDRMADTKTVSGAFTGSYVINPVSGER  383
            VLAPEH LV A+TT++Q +AV  Y  Q+  KS+L R   +K  +G  TGSY INPV+G  
Sbjct  260  VLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAINPVNGKE  319

Query  384  IQLWIADYVLAGYGTGAVMGVPSGDQRDWLFATHFNLPIVQILDAQQDIEHQADATKDGK  443
            + +WIADYVLA+YGTGA+M+VP+ D+RDW FA +FNL I+ +L++ +   ++A  T DG 
Sbjct  320  MPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGN--VEEAAFTEDGL  377

Query  444  YINSGFINGMNYTEATATLNAWLEEQGQGKAKINYRMRDAIFGRQRYWGEPIP-VYFKDG  502
             INS+F++G++ + A A +  WLE +G G+ ++ YR+RD +F+RQRYWGEPIP +   DG
Sbjct  378  HINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDG  437

Query  503  LPYLIKAEELPLLLPEIDKYLPTETGEPPLGRAEDW-----KyedeyeyeLSTMPGWAGS  557
             +  +   ELPL+LP      P+ TGE+PL+   DW             E +TMP WAGS
Sbjct  438  TSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVKGRRETNTMPQWAGS  497

Query  558  SWYWYRYMDAKNDSDFASAEAIKYWKDVDLYIGGAEHATGHLLYSRFWNKFLKDLGYVQE  617
            SWY  RY+D+ N   +A  E +K W  VD+Y+GGAEHA  HLLY+RFW+K L DLG V  
Sbjct  498  SWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPT  557

Query  618  EEPFKKLINQGMIQGRSNFVYRVIDEEGRGTNKLVSYGLRKDYKTSALHVDVNIVDNEVL  677
             EPF+KL+NQGMI G S   YR    ++RG+                      +V  + +
Sbjct  558  KEPFQKLFNQGMILGTS---YR----DSRGA----------------------LVATDKV  588

Query  678  NIEQFKLFRPEFADAEFILENGRYICGVEVEKMSKSKFNVVNPDVLIESYGADTLRMYEM  737
            +  +  +F+ E ++    LE++         KMSKS  NVVNPD ++E YGADTLR+YEM
Sbjct  589  EKRDGSFFHVETGEE---LEQAP-------AKMSKSLKNVVNPDDVVEQYGADTLRVYEM  638

Query  738  FLGPLEQSKPWNTNGIEGVFKFLRKFWRLFHNEAWTFHVNDSVPSKAELKALHKIIKKVQ  797
            F+GPL+ S +W+ +G+EG  KFL +  RL+       ++ +  ++  + K  +  +K V 
Sbjct  639  FMGPLDASIAWSEEGLEGSRKFLDRVYRLITTK----EITEENSGALD-KVYNETVKAVT  693

Query  798  DDVERFSFNTSVSSFMIAVNELTDLKCKNRQVLEDLVVVLSPYAPHICEELWMLLGNEAG  857
            ++V++  FNT+++ +M+ VN          +   ++V +++P+APH+ EELW  L   + 
Sbjct  694  EQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGE  753

Query  858  SLSYTPYPTFNPAYLVEDEFSYPVSVNGKTRLNLSMSLTLEAKEVEETVLANEDVQKYLE  917
            S+SY P P+++ + LVE++    V ++GK + +L ++  L   E++E  LANE VQ  + 
Sbjct  754  SISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIA  813

Query  918  GKAPKKVIVVKGRIVNIVI  936
            GK   KVI V  ++VNIVI
Sbjct  814  GKDIIKVIAVPNKLVNIVI  832


 Score =  185 bits (687),  Expect = 1e-47, Method: Compositional matrix adjust.
 Identities = 91/142 (65%), Positives = 119/142 (84%), Gaps = 0/142 (0%)

Query  3    YQFKEIEQKWQKFWAQHKTFKAADASNKPKFYVLDMFPYPSGAGLHVGHPLGYIASDIFS  62
            Y+   IE KWQ FWA++ TFK++  ++KPKFY LDMFPYPSGAGLHVGHP GY A+DI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRLKGFNVLHPMGYDSFGLPAEQYAIQTGQHPALTTEANINTYRKQLDGLGFSFDWSR  122
            R+KR +G NVLHPMG D+FGLPAEQYA++TG++PA  T  NI  +++Q+++LGFS+DW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVRTSDPEYYKWTQWIFMQLFN  144
            EV T+DP+YYKWTQWIF +L++
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYE  145

1739) Oweho_2745 in NC_016599


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  468 bits (1762),  Expect = 1e-132, Method: Compositional matrix adjust.
 Identities = 331/710 (47%), Positives = 463/710 (66%), Gaps = 53/710 (7%)

Query  204  LAYRAESTVNWCPALGTVLANDEV-KDGLSERGGHPVVQKKMMQWSLRITAYAQRLLDGL  262
            LAY AE  VNW   LGT +AN+EV  DG SERGG PVV+K M QW L+ITAYA+RLL++L
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  263  NEIDWSESLKESQRNWIGRSEGASVHFALKDREEKIEVFTTRPDTIFGVSFMVLAPENPL  322
            +E+DW+ES+K+ QRNWIG+S GA+V F +KD +  + VFTTRPDT+FG ++ VLAPE++L
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  323  VDEITTEAYRSSVDKYKVQAAKKSERDRLADVKTVSGQFTGAYAVHPFSGKELPIWIGDY  382
            VD ITT     +V  YK QA+ KS+  R    K  +G  TG+YA++P +GKE+P+WI+DY
Sbjct  268  VDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAINPVNGKEMPVWIADY  327

Query  383  VLASYGTGAVMSVPAHDSRDYAFAKYFDLPILPVVEGGDVSKESYDAKEGKVINSDFLNG  442
            VLASYGTGA+M+VPAHD RD  FAK F+L I+PV+EGG+V   ++ + +G  INSDFL+G
Sbjct  328  VLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEAAF-TEDGLHINSDFLDG  386

Query  443  LDvkeavakaiakieeeGLGKGKVNFRLRDAIFGRQRYWGEPIPVYY-KDGVPHSVKQEH  501
            LD   A+AK +  +E EG+G+ +V +RLRD +F+RQRYWGEPIP+    DG + +V + +
Sbjct  387  LDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESE  446

Query  502  LPLELPQVDAYLPTEDGEPPLARGQNW-NYDPEKGVVANGEGYPLEQTTMPGWAGSSWYD  560
            LPL LP      P+  GE+PLA   +W +   E GV +  E       TMP WAGSSWY 
Sbjct  447  LPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVKGRRET-----NTMPQWAGSSWYY  501

Query  561  LRYMDPFNTDAPVSEKADDYWQNVDLYIGGSEHATGHLLYTRFWHKFLKDQGIISQNEPF  620
            LRY+DP NT+    E     W  VD+Y+GG+EHA  HLLY+RFWHK L D G+++ +EPF
Sbjct  502  LRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPF  561

Query  621  KKLINQGMILGTSAFAYRVEGQNKFVSRGLRKDYKTVPVHVDVNTVNASDEMDVDAFKLW  680
            +KL+NQGMILGTS   YR        SRG           V  + V+  D          
Sbjct  562  QKLFNQGMILGTS---YR-------DSRG---------ALVATDKVEKRD----------  592

Query  681  RDDLAGAEFVSENGKFLVGREVEKMSKSKYNVVNPDDIIEQYGADTLRMYEMFLGPLEQS  740
                 G+ F  E G  L  +   KMSKS  NVVNPDD++EQYGADTLR+YEMF+GPL+ S
Sbjct  593  -----GSFFHVETGEEL-EQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDAS  646

Query  741  KPWNTAGITGVHGFLKKLTRLYKNEADWNISDEKADDKELKALHVLIKKVNEDIEAFSFN  800
             +W+  G+ G + FL ++ RL       +I++E+++  + K  +  +K V E+++   FN
Sbjct  647  IAWSEEGLEGSRKFLDRVYRLITTK---EITEENSGALD-KVYNETVKAVTEQVDQMKFN  702

Query  801  TSVSAFMICVNELGALKCNKL--EILEPLAVLISPFAPHLAEELWTGLGHEG-GISVVPF  857
            T+++ +M+ VN  +A K +KL  +    +  LI+PFAPHL+EELW +L   G +IS VP 
Sbjct  703  TAIAQLMVFVN--AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPW  760

Query  858  PIHNEDYLTENSFEYPVAFNGKMRFKEELSLEMAKDAVEKHIMGLEKTAT  907
            P  +E  L EN  E  V ++GK++ K  ++ +++++ ++   ++ EK  +
Sbjct  761  PSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQA  810


 Score =  179 bits (664),  Expect = 7e-46, Method: Compositional matrix adjust.
 Identities = 89/142 (63%), Positives = 116/142 (82%), Gaps = 0/142 (0%)

Query  3    YNFQEIEKKWQEYWAKNSSFKAEESSEKPKYYVLDMFPYPSGAGLHVGHPLGYIASDIVS  62
            Y+   IE KWQ +WA N +FK+   + KPK+Y LDMFPYPSGAGLHVGHP GY A+DI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRHKGFNVLHPMGYDSFGLPAEQYAIQTGQHPAITTEENIKRYRQQLDQIGFSFDWSR  122
            R+KR +G NVLHPMG D+FGLPAEQYA++TG++PA  T ENI  +++Q++ +GFS+DW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVRTSDPNFYKWTQWIFLQLFN  144
            EV T+DPN+YKWTQWIF +L++
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYE  145

1740) Sph21_0546 in NC_015277


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  468 bits (1763),  Expect = 8e-133, Method: Compositional matrix adjust.
 Identities = 313/718 (44%), Positives = 463/718 (65%), Gaps = 62/718 (8%)

Query  205  LAYLRESTVNWCPALGTVLANDEV-KDGVSERGGYPVIQKKMMQWSMRITAYAERLLQGL  263
            LAY  E  VNW   LGT +AN+EV  DG SERGGYPV++K M QW ++ITAYAERLL++L
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  264  DTVDWPEPLVEMQRNWIGKSIGASVKFALADGSDSIEVFTTRVDTIYGVSFLVLAPEHDL  323
            + VDWPE++ +MQRNWIGKS GA+V F + D    + VFTTR DT++G ++ VLAPEH L
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  324  VPIITTNVQRAQVENYIEQTKKKSERDRMADTKTVTGAFTGSYAMHPLTGKQVPIWIADY  383
            V  ITT+ Q   V +Y  Q+  KS+  R   +K  TG  TGSYA++P+ GK++P+WIADY
Sbjct  268  VDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAINPVNGKEMPVWIADY  327

Query  384  VLAGYGTGAVMAVPSGDQRDYLFAKQFHLPIIKILDIQEIDEEADSRKEGVYINSELING  443
            VLA+YGTGA+MAVP+ D+RD  FAKQF+L II +L+  ++ EEA    +G+ INS++++G
Sbjct  328  VLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNV-EEAAFTEDGLHINSDFLDG  386

Query  444  LSYQEAVSKLVSVLEERGIGKAKVNYRMRDAIFGRQRYWGEPVP-VYFKDGLPKLIKENE  502
            L    A++K+V  LE  G+G+ +V YR+RD +F+RQRYWGEP+P +   DG +  + E+E
Sbjct  387  LDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESE  446

Query  503  LPLLLPEVDKYLPTESGEPPLGRATNW---KYQGGYE--YELSTMPGWAGSSWYWYRYMD  557
            LPL+LP      P+ +GE+PL+  T+W     ++G     E +TMP WAGSSWY  RY+D
Sbjct  447  LPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYID  506

Query  558  SHNSEAFASKEAIDYWQAVDLYIGGSEHATGHLLYSRFWNKFLKDIGKVKEEEPFKKLIN  617
            +HN+E +A  E +  W +VD+Y+GG+EHA  HLLY+RFW+K L D+G V   EPF+KL+N
Sbjct  507  PHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFN  566

Query  618  QGMIQGRSNFVYRVLDEHGAGTNTFVSLGLKDQYKTTALHVDVNIVNNDILHLEKFRLSR  677
            QGMI G S   YR       +  ++V+ +  ++   + +HV+         +LE      
Sbjct  567  QGMILGTS---YR------DSRGALVATDKVEKRDGSFFHVETGE------ELE------  605

Query  678  PEYAEAKFILEDGKYVCGHEVEKMSKSKFNVVNPDDIIEQYGADTLRMYEMFLGPLEQSK  737
                              +   KMSKS  NVVNPDD++EQYGADTLR+YEMF+GPL+ S 
Sbjct  606  ------------------QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASI  647

Query  738  PWNTNGIEGVHKFLRKFWRLFHDASSNFSVSDEIPTKAELKSLHKIIRKVEDDIERFSFN  797
            +W+ +G+EG +KFL +  RL+        +++E +   + K  +  ++ V +++++  FN
Sbjct  648  AWSEEGLEGSRKFLDRVYRLITTK----EITEENSGALD-KVYNETVKAVTEQVDQMKFN  702

Query  798  TSVSSFMICVNELTDLRCNKRAIL-----RDLVIVLSPYAPHICEELWVLLGNEPGSLSY  852
            T+++ +M+ VN       NK   L     +++V +++P+APH+ EELW  L     S+SY
Sbjct  703  TAIAQLMVFVNA-----ANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISY  757

Query  853  TSYPVFNPDYLIEDEFEYPISFNGKMRLKLNLSLSLEGIEIEQVVLANEDVQRYLDGK  910
             + P ++   L+E++ E  + ++GK++ KL ++  L   E+++V LANE VQ  + GK
Sbjct  758  VPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGK  815


 Score =  182 bits (674),  Expect = 1e-46, Method: Compositional matrix adjust.
 Identities = 88/142 (62%), Positives = 115/142 (81%), Gaps = 0/142 (0%)

Query  3    YQFKTIEKKWQQFWASNQTFKVNNTSDKPKYYVLDMFPYPSGAGLHVGHPLGYIASDVFS  62
            Y+  +IE KWQ FWA N+TFK    + KPK+Y LDMFPYPSGAGLHVGHP GY A+D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRLRGYNVLHPMGYDSFGLPAEQYAIQTGQHPAITTETNIKRYREQLDNIGFSFDWSR  122
            R+KR +G NVLHPMG D+FGLPAEQYA++TG++PA  T  NI  ++ Q++ +GFS+DW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EIRTSDPSYYKWTQWIFMQLFN  144
            E+ T+DP+YYKWTQWIF +L++
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYE  145

1741) Srot_0244 in NC_014168


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  467 bits (1759),  Expect = 2e-132, Method: Compositional matrix adjust.
 Identities = 323/733 (45%), Positives = 477/733 (66%), Gaps = 59/733 (8%)

Query  216  ESVVNWCPGLGTVLSNEEVTDEGRSERGNFPVFRKSLRQWTMRITEYAdrliddldrldW  275
            E  VNW   LGT ++NEEV  +G SERG +PV RK++RQW ++IT YA+RL++DL+ +DW
Sbjct  153  EVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDLEEVDW  212

Query  276  PEKVKSMQRNWIGRSTGAVVSFPC--GEQVLEVFTTRPDTLYGVTFLVAAPESELVASLV  333
            PE +K MQRNWIG+STGA V+F     ++ + VFTTRPDTL+G T+ V APE  LV ++ 
Sbjct  213  PESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHALVDAI-  271

Query  334  PQAWPVGTDPRWTGSAATPAEAVATYRAKVANRAERERQE-DKAKTGVFTGAFAVNPLTQ  392
                          +++  AEAVA Y+ + + +++  R +  K KTGV TG++A+NP+  
Sbjct  272  --------------TTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAINPVNG  317

Query  393  ERIPVFVADYVLAGYGTGVVMAVPGHDQRDWDFAKTFGLPVAEVVSGGDVEIGAHTGEGQ  452
              +PV +ADYVLA+YGTG +MAVP+HD+RDW+FAK F L +  V+ GG+VE +A T +G 
Sbjct  318  KEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEAAFTEDGL  377

Query  453  LVNSGSWDGLSASEAKAVAADDLERLGVGRKQLQYKLRDWLFARQRYWGEPFPLVADESG  512
             +NS+  DGL  + A A   + LE  GVG  ++ Y+LRDWLF+RQRYWGEP+P++  E G
Sbjct  378  HINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDG  437

Query  513  QVFPLDDTALPVLLPQIEDFRPIVFDADDQDSRPSAPLKKAGDWLTVECDFGDGAQPYTR  572
               ++ ++ LP++LP   D+RP         +   +PL +  DWL V  +  DG +   R
Sbjct  438  TSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTDWLEVTRE--DGVKG-RR  486

Query  573  ETDVMPNWAGSCWYYLRYLDPKNEEAFCDPENERYWIGPRPDARGGADPGGVDLYVGGTE  632
            ET+ MP+WAGS WYYLRY+DP N E + D E  + W+              VD+YVGG+E
Sbjct  487  ETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWL-------------PVDIYVGGAE  533

Query  633  HAVLHLLYARFWHKVLHDLGYVSSAEPFRRLFNQGYIQAPSYTDSRGAYVPAAEVEERDG  692
            HAVLHLLYARFWHKVL DLG V++ EPF++LFNQG I + SY DSRGA V++  VE RDG
Sbjct  534  HAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDG  593

Query  693  EFFW--QGQPVKREFGKMGKSLKNSITPDEICDEYGADTLRVYEMSMGPLDQSKDWSTKD  750
             FF    G+ + +  +KM+KSLKN + PD++ ++YGADTLRVYEM MGPLD S  WS  +
Sbjct  594  SFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEG  653

Query  751  IVGAQRFLARVWRVVVDEQSGQACVVDAEPDAETVRALHRAIDQVGQEYAALKFNLAVAK  810
            + G+++FL RV R++   +      +  E  +   +  + ++  V ++   +KFN A+A+
Sbjct  654  LEGSRKFLDRVYRLITTKE------ITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQ  707

Query  811  LIEYTNYLTKRYLSGQQGAEGAPRAAVEPLVVMlaplaphlaeelWRRL-GHDELLVRHP  869
            L+ + N        + +  +         +V ++AP+APHL+EELW+ L + +E +   P
Sbjct  708  LMVFVN--------AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVP  759

Query  870  FPTADPAFLVDDEVKLPVQVAGKVRATIVVPAGVSEDVVRAAALADPKVVEHLAGKEPKR  929
             P+ D + LV+++V + VQ+ GKV+A +VV+ ++S + ++  ALA+ KV  ++AGK+  +
Sbjct  760  WPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIK  819

Query  930  VIVVPKKMVSIVL  942
            VI VP+K+V+IV+
Sbjct  820  VIAVPNKLVNIVI  832


 Score =  130 bits (478),  Expect = 3e-31, Method: Compositional matrix adjust.
 Identities = 74/153 (49%), Positives = 106/153 (70%), Gaps = 11/153 (7%)

Query  9    YDNATVRRIEEFWQAEWQRSGALHADNPTGELAGDGAAREPFFIMDMFPYPSGDGLHVGH  68
            YD+++   IE  WQA W  + ++ +        G +A++  F+ +DMFPYPSG GLHVGH
Sbjct  4    YDHTA---IEPKWQAFWADNHTFKT--------GTDASKPKFYALDMFPYPSGAGLHVGH  52

Query  69   PLGFIATDVFARFQRMAGKNVLHTMGFDSFGLPTEIYAVQTGTHPAAVTDRNVERFLRQI  128
            P G+ ATD+++RF+R  G NVLH MG D+FGLP+E YA++TG +PA  T  N+  F RQI
Sbjct  53   PEGYTATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQI  112

Query  129  RRIGLGHDERRRFKTSDPDYYRWTQWIFLKIYN  161
              +G++ D  R  +T+DP+YY+WTQWIF K+Y+
Sbjct  113  NALGFSYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1742) Lbys_0592 in NC_014655


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  466 bits (1757),  Expect = 3e-132, Method: Compositional matrix adjust.
 Identities = 313/731 (43%), Positives = 469/731 (65%), Gaps = 48/731 (6%)

Query  206  LTYLADSVVNFCPALGMVLSNDEV-KDGVSERGGYPVIQKKMSQWMMRITAYADRLIRGL  264
            L+Y A+  VN    LG  ++N+EV  DG SERGGYPV++K M QWM++ITAYA+RL+ +L
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  265  DEIDWSESLKEQQRNWIGKSVGASVKFKVENSDKEIEVFTTRVDTIYGVSYLVLAPEHEW  324
            +E+DW+ES+K+ QRNWIGKS GA+V FKV ++DK++ VFTTR DT++G +Y VLAPEH  
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  325  VAELTTPDQKAAVDKYIEDTQKRSELDRVSDVKTVSGAFTGSYCINPVNGERVPLWIADY  384
            V  +TT+DQ  AV  Y  ++  +S+L R    K  +G  TGSY INPVNG  +P+WIADY
Sbjct  268  VDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAINPVNGKEMPVWIADY  327

Query  385  VLAGYGTGAVMGVPSGDQRDWNFATHFNLPIVPILDTQKDLDKQADATKEGKYINSGMIN  444
            VLA+YGTGA+M+VP+ D+RDW+FA +FNL I+P+L+  +    +A  T +G  INS+ ++
Sbjct  328  VLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGN--VEEAAFTEDGLHINSDFLD  385

Query  445  GLEYKEATQKLISWLEENKIGKGKVNFRLRDAVFARQRYWGEPVPVYFKKNEEGRDIPYL  504
            GL+   A  K++ WLE + +G+ +V +RLRD +F+RQRYWGEP+P+    +  +  +P  
Sbjct  386  GLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVP--  443

Query  505  VSDKDLPLILPEIDKYQPTETGEPPLGRAANWTYTPEGESTAYPLEMSTMPGWAGSSWYW  564
              + +LPL+LP     +P+ TGE+PL+  ++W      ++     E +TMP WAGSSWY 
Sbjct  444  --ESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVKGRRETNTMPQWAGSSWYY  501

Query  565  FRYMDPKNKEAFASKEALDYWKDIDLYLGGTEHATGHLLYSRFWNKVLKDLGYVQEEEFA  624
            +RY+DP N E +A  E L  W  +D+Y+GG+EHA  HLLY+RFW+KVL DLG V   E  
Sbjct  502  LRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPF  561

Query  625  KKLINQGMIQGRSSFVYRVKNTAVPTFVSFGLKDQYEVTPLHVDVNIVDGDVLDVEKFKA  684
            +KL+NQGMI G S   YR    A+ +                  V+  DG  ++VE    
Sbjct  562  QKLFNQGMILGTS---YRDSRGALVA---------------TDKVEKRDGSFFHVE----  599

Query  685  TRNDIGDNPEFILENGKYICGSEVEKMSKSKFNVVNPDTLVEKFGADTLRLYEMFLGPLT  744
            T +++ + P                KMSKS  NVVNPD +VE++GADTLR+YEMF+GPL 
Sbjct  600  TGEELEQAP---------------AKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLD  644

Query  745  ESKPWDTKGIEGTSRFLRKLWRLYFDPNFRVEEVEPTKENLKTLHKTIKKVQEDIENFSF  804
             S +W   G+EG+ +FL ++ RL    ++  E+  +     K  + T+K V E++++  F
Sbjct  645  ASIAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALD---KVYNETVKAVTEQVDQMKF  701

Query  805  NTSVSTFMIAVNEFTEQKCKSKSVLRDFLIVISPYAPHIAEELWEALGEKA-SITLASYP  863
            NT+++ +M+ VN    +        ++F+ +I+P+APH++EELW+AL   + SI+  + P
Sbjct  702  NTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWP  761

Query  864  QWNAEFLKEDAFEYPIQVNGKVRLNLSFsaeaskeeiekaVLENEQVIRWMEGKPLKKII  923
              +   L E+  E  +Q++GKV+ +L  + + S+EE++   L NE+V   + GK + K+I
Sbjct  762  SYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVI  821

Query  924  VVPKRIVNVVI  934
             VP+++VN+VI
Sbjct  822  AVPNKLVNIVI  832


 Score =  182 bits (674),  Expect = 1e-46, Method: Compositional matrix adjust.
 Identities = 92/145 (64%), Positives = 116/145 (80%), Gaps = 0/145 (0%)

Query  1    MAEYNHREIEKKWQKYWEDHQTYKVEIDKSKPKFYVLDMFPYPSGAGLHVGHPLGYIASD  60
            M+ Y+H  IE KWQ +W D++T+K   D SKPKFY LDMFPYPSGAGLHVGHP GY A+D
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   IYSRFKRLKGFNVLHPMGFDSFGLPAEQYAIQTGQHPAITTEKNINTYIAQLKNIGFSYD  120
            I SRFKR +G NVLHPMG D+FGLPAEQYA++TG++PA  T  NI  +  Q++ +GFSYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WSREVRTSEPDYYKWTQWIFCQIFN  145
            W REV T++P+YYKWTQWIF ++++
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYE  145

1743) Tgr7_2279 in NC_011901


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  466 bits (1755),  Expect = 3e-132, Method: Compositional matrix adjust.
 Identities = 341/845 (41%), Positives = 513/845 (61%), Gaps = 73/845 (8%)

Query  5    YEPDALERQAQTWWDEHQTFRAREDAPGEPFYCLSMFPYPSGR-LHMGHVRNYTIGDVIS  63
            Y+  A+E + Q+ W +++TF++  DA+   FY L MFPYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMQGRNVLQPMGWDAFGLPAENAAIKHLVPPAKWTYENIAYMRGQLQRLGFGYDWDR  123
            R++R QG+NVL+PMGWDAFGLPAE+ A+     PA  T ENIA  + Q++ LGF+YDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  ELATCRPEYYRWEQWLFTRLVKKGLAYKKTAMVNWDPVDQTVLANEQVI-DGKGWRSGAP  182
            E+ T  P+YY+W QW+FT+L  KGLAY     VNW     T +ANE+V+ DG + R+G P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VERREIPQWFLRITDYAeellkgldglegWPEQVRTMQRNWIGRSEGVELEFEVPG-EAP  241
            V R+ + QW L+IT YA E L       +WPE ++ MQRNWIG+S G ++ F V + +  
Sbjct  184  VVRKPMRQWMLKITAYA-ERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKD  242

Query  242  LTVYTTRPDTLMGVSYVGVAPEHPL--AARAAEGDGKLAAFI-EACRHTKVSEADMATLE  298
            +TV+TTRPDTL G +Y  +APEH+L  A  +++    +A +  +A   + ++ +D+A  E
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAK-E  301

Query  299  KKGMDTGLKAVHPVTGEPVPVWVANFVLMEYGTGAVMAVPAHDQRDWEFARQYGLPVRQV  358
            K G+ TG  A++PV G  +PVW+A++VL  YGTGA+MAVPAHD+RDWEFA+Q+ L     
Sbjct  302  KTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLD----  357

Query  359  ILPAEEGVAVDLDQAAFTDKGVLIESAQFNGLSSAQAFDAIADFLEKQHKGRRRVNYRLR  418
            I+P  EG  V  ++AAFT+ G+ I+S  ++GL  A A+  + + LE +  G   V YRLR
Sbjct  358  IIPVLEGGNV--EEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLR  415

Query  419  DWGVSRQRYWGCPIPII---NCPDCGpvpvpeeqlpvvlpedvAFDGVGSPIKRMPEFID  475
            DW  SRQRYWG PIPII   +    +        +  V  +  + +   SP+  + + ++
Sbjct  416  DWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLE  475

Query  476  TTCPECGGKAERETDTFDTFFESSWYYARYTCKDADGAMLDER-ARHWLPVDQYIGGIEH  534
             T  + G K+ RET+T      SSWYY RY   +    + DE   ++WLPVD Y+GG EH
Sbjct  476  VTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEH  534

Query  535  AVLHLLYARFFHKLMRDEGLVDGDEPFTRLLTQGMVL-------------------KDG-  574
            AVLHLLYARF HK++ D G+V   EPF +L+ QGM+L                   +DG 
Sbjct  535  AVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGS  594

Query  575  --------------AKMSKSKGNTVDPEALIERYGADTVRLFMMFAAPPELSLEWSDSGV  620
                          AKMSKS  N V+P+ ++E+YGADT+R++ MF +P + S+ WS+ G+
Sbjct  595  FFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGL  654

Query  621  EGAYRFLKRLWKQVHDHVQGGaapaldkaalnadQQALRRKLHQTLAKVSDDIGRRTTFN  680
            EG+ +FL R+ + +                 + +  AL +  ++T+  V++++++   FN
Sbjct  655  EGSRKFLDRVYRLITTK-----------EITEENSGALDKVYNETVKAVTEQVDQM-KFN  702

Query  681  TAIAACMELMNELGRFEDKSGQGRAVMQEALETTVLMLSPIVPHIAHALWSELGREGAAV  740
            TAIA       +L  F + + +   +  +     V +++P+ PH+++ LW  L   G ++
Sbjct  703  TAIA-------QLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESI  755

Query  741  D-QPWPVVDESALESDTVELVVQVNGKlraqiqvpaaaaraaieeaalaDENVQRHIEGK  799
               PWP  DES L  + VE+VVQ++GK++A++ V+   +R  ++E ALA+E+VQ +I GK
Sbjct  756  SYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGK  815

Query  800  TVVKM  804
             ++K+
Sbjct  816  DIIKV  820

1744) leuS in NC_021150


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  465 bits (1753),  Expect = 5e-132, Method: Compositional matrix adjust.
 Identities = 360/886 (41%), Positives = 557/886 (63%), Gaps = 76/886 (8%)

Query  5    YQPREIEAAAQSIWDAQKSFEVREQPGKDTFYCLSMFPYPSGK-LHMGHVRNYTIGDVIA  63
            Y+   IE+  Q++W  + +F    +++K  FY L MFPYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMQGRNVLQPMGWDAFGMPAENAAMKNRVAPAKWTYENIAYMKSQLKSLGLGIDWSR  123
            R++R QG+NVL+PMGWDAFG+PAE+ AM     PA  T ENIA  K Q+++LG++ DW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVTTCKPDYYRWEQWLFTRLFEKGVIYRKNGTVNWDPVDQTVLANEQVI-DGRGWRSGAL  182
            EV T  P+YY+W QW+FT+L+EKG+ Y  +  VNW     T +ANE+V+ DG + R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VEKREIPMYYFRITAYAEELLQSLDSLPGWPEQVKTMQRNWIGKSYGADIVFDYDQASVG  242
            V ++ +    ++ITAYAE LL+ L+ + +WPE +K MQRNWIGKS GA++ F   ++   
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTD--  240

Query  243  EAGQLRVYSTRPDTLMGATYVAVAAEHPLAQRAAANDPALAAFIAECKAGSVAEADMA--  300
               ++ V++TRPDTL GATY  +A+EH+L +  +++D A A  +A+ K  +   +D+A  
Sbjct  241  --KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEA--VADYKRQASLKSDLART  296

Query  301  --TMEKKGLATGQFVVHPLTGDRLPVFVANYVLWGYGEGAVMAVPAHDERDFEFANKYGL  358
              + EK G+ TG + ++P+ G  +PV +A+YVL +YG GA+MAVPAHDERD EFA+++ L
Sbjct  297  DLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNL  356

Query  359  PIRQVYAAEGRDFSASEWQAWYADKEGLTTVDSGKYDGKSFTEAFDAIVADLEATGHGAR  418
             I  V  +   + +A      +++ +GL  ++S+  DG   + A+  +V  LEA G G  
Sbjct  357  DIIPVLEGGNVEEAA------FTE-DGL-HINSDFLDGLDKASAIAKMVEWLEAEGVGNE  408

Query  419  KTQFRLRDWGISRQRYWGCPIPIIH--CEACGdvpvpeeqlpvvlpedvvpdGTG-SPLA  475
            +  +RLRDW +SRQRYWG PIPIIH    +   VP +E  L + +  D+ P GTG SPLA
Sbjct  409  NVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLA  468

Query  476  KMPEFYECACPKCGKPAKRETDTMDTFVESSWYYARYASPQYAGGMVDPQAADHWLPVDQ  535
            ++ +  E +     K ++RET+TM     SSWYY RY  P+ +  + D +   +WLPVD 
Sbjct  469  NVTDWLEVTREDGVK-GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDI  527

Query  536  YIGGIEHAILHLLYARFFHKLMRDEGLLSSDEPFENLLTQGMVVAETYYRTLENGGKDWF  595
            Y+GG EHA+LHLLYARF HK++ D G++++ EPF++L+ QGM+++ +Y            
Sbjct  528  YVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY------------  575

Query  596  NPADVEVERDARAKVIGARL--KSDG--LPVEIG-----GTEKMSKSKNNGVDPQAMIDA  646
                    RD+R+ ++++    K DG  + VE G     +  KMSKS +N V+P+ +++ 
Sbjct  576  --------RDSRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQ  627

Query  647  YGADTCRLFMMFAAPPELSLEWSDAGVEGASRFLRRVWRLAHA-HVGAGLPGTLDKARLS  705
            YGADT R++ MF +P + S+ WS+ G+EG+ +FL RV RL  + ++    +G+LDK    
Sbjct  628  YGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALDK----  683

Query  706  DAQKEIRRAIHLAIRQASQDVGQHHKFNTAIAQVMTLMNVLEKAPAADEQDRALLQEGLE  765
                      + +++  +++V ++ KFNTAIAQ+M ++N      AA+ +D+ L+ +   
Sbjct  684  --------VYNETVKAVTEQV-DQMKFNTAIAQLMVFVN------AANKEDK-LFSDYAK  727

Query  766  TVALLLAPITPHICHALWEALGKDGLIID-AAWPTVDETAlvqdtltlvvqvNGKLRGEI  824
                L+AP++PH+ + LW+AL   G  I   +WP+ DE+ LV++ + +VVQ++GK+++ +
Sbjct  728  GFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKL  787

Query  825  QVPaaasreeieaaaranenVLRFTEGLAIRKVIVVPGKLVNIVAN  870
             V+   SREE++  A ANE+V     G  I KVI VP KLVNIV +
Sbjct  788  VVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

1745) leuS in NC_021149


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  465 bits (1753),  Expect = 5e-132, Method: Compositional matrix adjust.
 Identities = 360/886 (41%), Positives = 557/886 (63%), Gaps = 76/886 (8%)

Query  5    YQPREIEAAAQSIWDAQKSFEVREQPGKDTFYCLSMFPYPSGK-LHMGHVRNYTIGDVIA  63
            Y+   IE+  Q++W  + +F    +++K  FY L MFPYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMQGRNVLQPMGWDAFGMPAENAAMKNRVAPAKWTYENIAYMKSQLKSLGLGIDWSR  123
            R++R QG+NVL+PMGWDAFG+PAE+ AM     PA  T ENIA  K Q+++LG++ DW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVTTCKPDYYRWEQWLFTRLFEKGVIYRKNGTVNWDPVDQTVLANEQVI-DGRGWRSGAL  182
            EV T  P+YY+W QW+FT+L+EKG+ Y  +  VNW     T +ANE+V+ DG + R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VEKREIPMYYFRITAYAEELLQSLDSLPGWPEQVKTMQRNWIGKSYGADIVFDYDQASVG  242
            V ++ +    ++ITAYAE LL+ L+ + +WPE +K MQRNWIGKS GA++ F   ++   
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTD--  240

Query  243  EAGQLRVYSTRPDTLMGATYVAVAAEHPLAQRAAANDPALAAFIAECKAGSVAEADMA--  300
               ++ V++TRPDTL GATY  +A+EH+L +  +++D A A  +A+ K  +   +D+A  
Sbjct  241  --KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEA--VADYKRQASLKSDLART  296

Query  301  --TMEKKGLATGQFVVHPLTGDRLPVFVANYVLWGYGEGAVMAVPAHDERDFEFANKYGL  358
              + EK G+ TG + ++P+ G  +PV +A+YVL +YG GA+MAVPAHDERD EFA+++ L
Sbjct  297  DLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNL  356

Query  359  PIRQVYAAEGRDFSASEWQAWYADKEGLTTVDSGKYDGKSFTEAFDAIVADLEATGHGAR  418
             I  V  +   + +A      +++ +GL  ++S+  DG   + A+  +V  LEA G G  
Sbjct  357  DIIPVLEGGNVEEAA------FTE-DGL-HINSDFLDGLDKASAIAKMVEWLEAEGVGNE  408

Query  419  KTQFRLRDWGISRQRYWGCPIPIIH--CEACGdvpvpeeqlpvvlpedvvpdGTG-SPLA  475
            +  +RLRDW +SRQRYWG PIPIIH    +   VP +E  L + +  D+ P GTG SPLA
Sbjct  409  NVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLA  468

Query  476  KMPEFYECACPKCGKPAKRETDTMDTFVESSWYYARYASPQYAGGMVDPQAADHWLPVDQ  535
            ++ +  E +     K ++RET+TM     SSWYY RY  P+ +  + D +   +WLPVD 
Sbjct  469  NVTDWLEVTREDGVK-GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDI  527

Query  536  YIGGIEHAILHLLYARFFHKLMRDEGLLSSDEPFENLLTQGMVVAETYYRTLENGGKDWF  595
            Y+GG EHA+LHLLYARF HK++ D G++++ EPF++L+ QGM+++ +Y            
Sbjct  528  YVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY------------  575

Query  596  NPADVEVERDARAKVIGARL--KSDG--LPVEIG-----GTEKMSKSKNNGVDPQAMIDA  646
                    RD+R+ ++++    K DG  + VE G     +  KMSKS +N V+P+ +++ 
Sbjct  576  --------RDSRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQ  627

Query  647  YGADTCRLFMMFAAPPELSLEWSDAGVEGASRFLRRVWRLAHA-HVGAGLPGTLDKARLS  705
            YGADT R++ MF +P + S+ WS+ G+EG+ +FL RV RL  + ++    +G+LDK    
Sbjct  628  YGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALDK----  683

Query  706  DAQKEIRRAIHLAIRQASQDVGQHHKFNTAIAQVMTLMNVLEKAPAADEQDRALLQEGLE  765
                      + +++  +++V ++ KFNTAIAQ+M ++N      AA+ +D+ L+ +   
Sbjct  684  --------VYNETVKAVTEQV-DQMKFNTAIAQLMVFVN------AANKEDK-LFSDYAK  727

Query  766  TVALLLAPITPHICHALWEALGKDGLIID-AAWPTVDETAlvqdtltlvvqvNGKLRGEI  824
                L+AP++PH+ + LW+AL   G  I   +WP+ DE+ LV++ + +VVQ++GK+++ +
Sbjct  728  GFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKL  787

Query  825  QVPaaasreeieaaaranenVLRFTEGLAIRKVIVVPGKLVNIVAN  870
             V+   SREE++  A ANE+V     G  I KVI VP KLVNIV +
Sbjct  788  VVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

1746) leuS in NC_012560


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  465 bits (1753),  Expect = 5e-132, Method: Compositional matrix adjust.
 Identities = 360/886 (41%), Positives = 557/886 (63%), Gaps = 76/886 (8%)

Query  5    YQPREIEAAAQSIWDAQKSFEVREQPGKDTFYCLSMFPYPSGK-LHMGHVRNYTIGDVIA  63
            Y+   IE+  Q++W  + +F    +++K  FY L MFPYPSG  LH+GH   YT  D+++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYQRMQGRNVLQPMGWDAFGMPAENAAMKNRVAPAKWTYENIAYMKSQLKSLGLGIDWSR  123
            R++R QG+NVL+PMGWDAFG+PAE+ AM     PA  T ENIA  K Q+++LG++ DW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVTTCKPDYYRWEQWLFTRLFEKGVIYRKNGTVNWDPVDQTVLANEQVI-DGRGWRSGAL  182
            EV T  P+YY+W QW+FT+L+EKG+ Y  +  VNW     T +ANE+V+ DG + R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  183  VEKREIPMYYFRITAYAEELLQSLDSLPGWPEQVKTMQRNWIGKSYGADIVFDYDQASVG  242
            V ++ +    ++ITAYAE LL+ L+ + +WPE +K MQRNWIGKS GA++ F   ++   
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTD--  240

Query  243  EAGQLRVYSTRPDTLMGATYVAVAAEHPLAQRAAANDPALAAFIAECKAGSVAEADMA--  300
               ++ V++TRPDTL GATY  +A+EH+L +  +++D A A  +A+ K  +   +D+A  
Sbjct  241  --KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEA--VADYKRQASLKSDLART  296

Query  301  --TMEKKGLATGQFVVHPLTGDRLPVFVANYVLWGYGEGAVMAVPAHDERDFEFANKYGL  358
              + EK G+ TG + ++P+ G  +PV +A+YVL +YG GA+MAVPAHDERD EFA+++ L
Sbjct  297  DLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNL  356

Query  359  PIRQVYAAEGRDFSASEWQAWYADKEGLTTVDSGKYDGKSFTEAFDAIVADLEATGHGAR  418
             I  V  +   + +A      +++ +GL  ++S+  DG   + A+  +V  LEA G G  
Sbjct  357  DIIPVLEGGNVEEAA------FTE-DGL-HINSDFLDGLDKASAIAKMVEWLEAEGVGNE  408

Query  419  KTQFRLRDWGISRQRYWGCPIPIIH--CEACGdvpvpeeqlpvvlpedvvpdGTG-SPLA  475
            +  +RLRDW +SRQRYWG PIPIIH    +   VP +E  L + +  D+ P GTG SPLA
Sbjct  409  NVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLA  468

Query  476  KMPEFYECACPKCGKPAKRETDTMDTFVESSWYYARYASPQYAGGMVDPQAADHWLPVDQ  535
            ++ +  E +     K ++RET+TM     SSWYY RY  P+ +  + D +   +WLPVD 
Sbjct  469  NVTDWLEVTREDGVK-GRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDI  527

Query  536  YIGGIEHAILHLLYARFFHKLMRDEGLLSSDEPFENLLTQGMVVAETYYRTLENGGKDWF  595
            Y+GG EHA+LHLLYARF HK++ D G++++ EPF++L+ QGM+++ +Y            
Sbjct  528  YVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSY------------  575

Query  596  NPADVEVERDARAKVIGARL--KSDG--LPVEIG-----GTEKMSKSKNNGVDPQAMIDA  646
                    RD+R+ ++++    K DG  + VE G     +  KMSKS +N V+P+ +++ 
Sbjct  576  --------RDSRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQ  627

Query  647  YGADTCRLFMMFAAPPELSLEWSDAGVEGASRFLRRVWRLAHA-HVGAGLPGTLDKARLS  705
            YGADT R++ MF +P + S+ WS+ G+EG+ +FL RV RL  + ++    +G+LDK    
Sbjct  628  YGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALDK----  683

Query  706  DAQKEIRRAIHLAIRQASQDVGQHHKFNTAIAQVMTLMNVLEKAPAADEQDRALLQEGLE  765
                      + +++  +++V ++ KFNTAIAQ+M ++N      AA+ +D+ L+ +   
Sbjct  684  --------VYNETVKAVTEQV-DQMKFNTAIAQLMVFVN------AANKEDK-LFSDYAK  727

Query  766  TVALLLAPITPHICHALWEALGKDGLIID-AAWPTVDETAlvqdtltlvvqvNGKLRGEI  824
                L+AP++PH+ + LW+AL   G  I   +WP+ DE+ LV++ + +VVQ++GK+++ +
Sbjct  728  GFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKL  787

Query  825  QVPaaasreeieaaaranenVLRFTEGLAIRKVIVVPGKLVNIVAN  870
             V+   SREE++  A ANE+V     G  I KVI VP KLVNIV +
Sbjct  788  VVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK  833

1747) leuS in NC_018649


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  464 bits (1748),  Expect = 1e-131, Method: Compositional matrix adjust.
 Identities = 297/673 (45%), Positives = 432/673 (65%), Gaps = 46/673 (6%)

Query  70   SLYPFDEIETAVQKRWKQENAFALKDQPSKKTFYCLEMFPYPSGR-IHMGHVRNYSIGDA  128
            ++Y    IE   Q  W ++++F    ++SK  FY L+MFPYPSG  +H+GH   Y+  D 
Sbjct  2    TFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDI  61

Query  129  LARYKRMRGFNVLHPMGWDSFGLPAENAAIQRGIHPAVWTEQNIAHMKEQLSRLGLSYDW  188
            L+R+KR +G NVLHPMGWD+FGLPAE+ A++ G +PA  T +NIA+ K Q++ LG+SYDW
Sbjct  62   LSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDW  121

Query  189  SLEVTTCLPEYYRWNQWFFLKFYEKGLAYKKEGLLNWCDSCLTVLANEQV-EEGLCWRCK  247
              EV T  P+YY+W QW+F K+YEKGLAY  E  +NW +   T +ANE+V  +G   R  
Sbjct  122  DREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGG  181

Query  248  SPVTLRPMEQWYLRITDYAQELLDAIPDLQGWPEKVRVMQENWIGKSEGAEIRFSVEGSS  307
             PV  +PM QW L+IT YA+ LL+ + +++ WPE ++ MQ NWIGKS GA++ F V ++ 
Sbjct  182  YPVVRKPMRQWMLKITAYAERLLEDLEEVD-WPESIKDMQRNWIGKSTGANVTFKVKDTD  240

Query  308  LELSVFTTRPDTLFGVTFVTIApehplleellplSRQREETESFIRKVLHKRATERNTEP  367
             +++VFTTRPDTLFG T+  +A  +  L + +  S Q E    + R+   K    R   +
Sbjct  241  KDFTVFTTRPDTLFGATYAVLA-PEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA  299

Query  368  GEKEGIDTGLRVIHPLTGDHLPLWIGNFVVASYGTGVVMGVPAHDERDHEFARKYGLPIK  427
             EK G+ TG   I+P+ G ++P+WI+++V+ASYGTG +M+VPAHDERD EFA+++ L I 
Sbjct  300  KEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDII  359

Query  428  EVIAPSVAHEPHAPEMAYTGPGRLIHSGAFNGLSNELAKGKIISELETRGKGVRKVTYRL  487
             V+  +  +E+     A+T  G  I+S+ ++GL +  A +K++  LE+ G G  +VTYRL
Sbjct  360  PVLEGGNVEEA-----AFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRL  414

Query  488  RDWGISRQRYWGTPIPIIYCETCGTVPVPESELPVILP--RDVAFTGKGGSPLRDSESFF  545
            RDW +SRQRYWG PIPII  E   + +VPESELP++LP  +D+  +G G SPL +    +
Sbjct  415  RDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWL  474

Query  546  RTTCPNCQAPARRETDTMDTFFDSSWYFLRFTDPSNTAEPFSKIAARQWIPVDQYIGGVE  605
              T  +    +RRET+TM    +SSWY+LR+ DP NT         +QW+PVD Y+GG E
Sbjct  475  EVTREDG-VKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAE  533

Query  606  HAILHLLYSRFFTRALKDLGFVDSPEPFRALLTQGMVL-------------------KDG  646
            HA+LHLLY+RF  + L DLG V + EPF+ L+ QGM+L                   +DG
Sbjct  534  HAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDG  593

Query  647  S---------------KMSKSKGNVVDPDQLIERYGADTVRLFTLFSAPPDKDLAWDDKA  691
            S               KMSKS  NVV+PD+++E+YGADT+R++ +F +P D  +AW + +
Sbjct  594  SFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEG  653

Query  692  VEGAYRFLGRLYQ  704
            +EG+ +FL+R+Y+
Sbjct  654  LEGSRKFLDRVYR  666


 Score = 56.3 bits (194),  Expect = 9e-09, Method: Compositional matrix adjust.
 Identities = 27/74 (37%), Positives = 50/74 (68%), Gaps = 0/74 (0%)

Query  819  PWPEAREEAMIRDEIPYVIQINGKLRATLMLPPDIDRSELLKKALEDERIQRNLVDMKLQ  878
            PWP   E  ++ +++  V+QI+GK++A L+++ D+ R EL   AL +E++Q ++ +  + 
Sbjct  759  PWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDII  818

Query  879  KEIYVPGKLLNLVV  892
            K I VP KL+N+V+
Sbjct  819  KVIAVPNKLVNIVI  832

1748) leuS in NC_009441


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  463 bits (1744),  Expect = 3e-131, Method: Compositional matrix adjust.
 Identities = 311/745 (42%), Positives = 471/745 (64%), Gaps = 68/745 (9%)

Query  216  MTYLAETEVNWCPGLGTVLANDEIV-NGVSERGGFPVIRKKMTQWSMRISAYAERLLQGL  274
            ++Y AE  VNW   LGT +AN+E++ +G SERGG+PV+RK M QW ++I+AYAERLL++L
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  275  NDIDWSESIKESQRNWIGKSVGALVTFNVKNHDEVIEVFTTRPDTIFGVTFMTLAPEHDL  334
            +++DW+ESIK+ QRNWIGKS GA VTF+VK+ D  + VFTTRPDT+FG T+  LAPEH L
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  335  VAKITTPEQKEAVEAYIEKTAKRSERERMADVKTISGVFTGAYAEHPFTKEAIPVWIGDY  394
            V  ITT++Q EAV  Y  +++ +S+  R    K  +GV TG+YA +P     +PVWI+DY
Sbjct  268  VDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAINPVNGKEMPVWIADY  327

Query  395  VLAGYGTGAVMAVPCGDERDYAFANFFKGQNGMQEIKNIFANVDISEAAYGSKDNVEIAA  454
            VLA+YGTGA+MAVP  DERD  FA+ F+      +I  ++   ++ EAA+ + D ++I  
Sbjct  328  VLASYGTGAIMAVPAHDERDWEFAKQFN-----LDIIPVLEGGNVEEAAF-TEDGLHI-N  380

Query  455  SDFLNGLNYKDATAKAIYKLEEIGQGKGKTNYRLRDAVFSRQRYWGEPFP-VYYVNGLPK  513
            SDFL+GL+   A AK +  LE  G G+ +  YRLRD +FSRQRYWGEP+P +   +G + 
Sbjct  381  SDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTST  440

Query  514  MIDTQHLPIILPEVEKYLPTEDGLPPLGNAAVWAWDIKENKVVNTDLVDNVSIFPLELNT  573
             +   +LP++LP      P+  G +PL+N + W  ++  +  V+            E NT
Sbjct  441  AVPESELPLVLPVTKDIRPSGTGESPLANVTDWL-EVTREDGVKG---------RRETNT  490

Query  574  MPGWAGSSWYWMRYMDAHNENEFASKEALAYWENVDLYIGGSEHATGHLLYSRFWNKFLK  633
            MP WAGSSWY +RY+D+HN + +A  E L  W  VD+Y+GG+EHA  HLLY+RFW+K L 
Sbjct  491  MPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWHKVLY  550

Query  634  DKGFAPTEEPFKKLINQGMILGTTAYVYRLEGTNTFVSKNKIKGQNVQPIRVDVHFVNSS  693
            D G  PT EPF+KL+NQGMILGT+   YR ++  ++V+ +K+  ++   ++V+     ++
Sbjct  551  DLGVVPTKEPFQKLFNQGMILGTS---YR-DSRGALVATDKVEKRDGSFFHVE-----TG  601

Query  694  DELNIEKFKAWREDFNTAEFIFDENGKYIVGREVEKMSKSYYNVVTPDDICAEYGADTLR  753
            +EL+                           +   KMSKS  NVV PDD+  +YGADTLR
Sbjct  602  EELE---------------------------QAPAKMSKSLKNVVNPDDVVEQYGADTLR  634

Query  754  LYEMFLGPLEQAKPWNTAGISGVFGFLKKLWRLYFDDNGLIVNNDEPTKDNLKSLHK---  810
            +YEMF+GPL+ + +W+  G+ G   FL ++ RL        +   E T +N  +L+K   
Sbjct  635  VYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRL--------ITTKEITEENSGALDKVYN  686

Query  811  -TIKKVAEDIENFSFNTSVSQFMICVNELSSQNCHSRAILEPLAILVSPYAPHIAEELWA  869
             T+K V+E++++  FNT+++Q+M+ VN  + ++         +  L++P+APH++EELW 
Sbjct  687  ETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  870  QLGHKT-SISEVAFPVFDAKHLVETNKEYPVSFNGKMRFTIELPLDLTAAQIEEIVMKDE  928
             L     SIS V+ P +D   LVE + E  V ++GK++  + ++ DL+  +++E+ + +E
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  929  RTQKQLDGRIPNKVIIVPGKIINLV  953
            + Q ++ G+   KVI VP K++N+V
Sbjct  807  KVQAEIAGKDIIKVIAVPNKLVNIV  831


 Score =  167 bits (619),  Expect = 2e-42, Method: Compositional matrix adjust.
 Identities = 86/153 (57%), Positives = 116/153 (76%), Gaps = 11/153 (7%)

Query  3    YNPNEIEAKWQKYWAENQTFAAKNNSEKPKHYVLDMFPYPSGAGLHVGHPLGYIASDVYS  62
            Y+   IE+KWQ +WA+N+TF +  ++ KPK Y LDMFPYPSGAGLHVGHP GY A+D+ S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RFKRHQGFNVLHPMGYDSFGLPAEQYAIQTGQRPEDTTRVNIDGGVDKEGKQIAGYRKQL  122
            RFKR QG NVLHPMG D+FGLPAEQYA++TG+ P + T           + +IA +++Q+
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFT-----------AENIANFKRQI  112

Query  123  DKIGFSFDWAREVRTSNPDYYKHTQWIFIQLFN  155
            + +GFS+DW REV T++P+YYK TQWIF +L++
Sbjct  113  NALGFSYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1749) leuS in NC_015576


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  462 bits (1742),  Expect = 4e-131, Method: Compositional matrix adjust.
 Identities = 338/737 (46%), Positives = 491/737 (67%), Gaps = 54/737 (7%)

Query  216  LVYRSDSMVNWCPGLGTVLANEEVTADGRSDRGNFPVFRKRLRQWMMRITAYSdrllddl  275
            L Y ++  VNW   LGT +ANEEV +DG S+RG +PV RK +RQWM++ITAY++RLL+DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  276  dvldWPEKVKTMQRNWIGRSTGAAALFGADTTDGAEVDIEVFTTRPDTLFGASYLVLAPE  335
            + +DWPE +K MQRNWIG+STGA   F    TD    D+ VFTTRPDTLFGA+Y VLAPE
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDK---DFTVFTTRPDTLFGATYAVLAPE  264

Query  336  HDLVDRLTVADWPDGVDQRWTFGSATPaeavaayrkaiaaKSDLERQE-NKTKTGVFLGS  394
            H LVD +T +D +++V +   +   ++             KSDL R +  K KTGV  GS
Sbjct  265  HALVDAITTSDQAEAVAD---YKRQASL------------KSDLARTDLAKEKTGVWTGS  309

Query  395  YATNPANGQQVPIFIADYVLAGYGTGAIMAVPGHDQRDWEFAAEFGLPVVEVIAGGDISE  454
            YA NP NG+++P+ IADYVLA+YGTGAIMAVP+HD+RDWEFA +F L ++ V+ GG++ E
Sbjct  310  YAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEE  369

Query  455  AAYAGDGTLVNSGPLNGMTVDDAKQAITRQLESQGRGWARIEFKLRDWLFARQRYWGEPF  514
            AA++ DG  +NS+ L+G+    A   +   LE++G G   + ++LRDWLF+RQRYWGEP+
Sbjct  370  AAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPI  429

Query  515  PIVFDADGRPHALDSAALPVELPDVGDYSPVLFdpddassepsppLAKATDWVHVELDLG  574
            PI+   DG + A+  + LP+ LP   D  P        S+   +PLA+ TDW++V  +  
Sbjct  430  PIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTDWLEVTRE--  479

Query  575  DGLQPYTRDTNVMPQWAGSSWYELRYADPRNADQFCAPENEAYWMGPRPAEHGPDDPGGV  634
            DG++   R+TN MPQWAGSSWY LRY DP+N++++   E    W+              V
Sbjct  480  DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWL-------------PV  525

Query  635  DLYVGGAEHAVLHLLYCRFWHKVLYDLGHVSSREPYRRLVNQGYIQAAAYTDSRGSYVPA  694
            D+YVGGAEHAVLHLLY RFWHKVLYDLG V+++EP+++L NQG I +++Y DSRG+ V++
Sbjct  526  DIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVAT  585

Query  695  VDVVERDGKFYLPGPDGDTEVFAEYGKMGKSLKNSVSPDEICDAYGADTLRVYEMSMGPL  754
              V  RDG F+    + + E  +  +KM+KSLKN V+PD++ + YGADTLRVYEM MGPL
Sbjct  586  DKVEKRDGSFFHVETGEELEQAP--AKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPL  643

Query  755  EMSRPWATKDVVGAHRFLQRVWRLIVDEETGATRVLDAEPDTETLRLLHRTIVGVSEDYA  814
            + S +W+  ++ G+++FL+RV RLI      +T+ +  E      ++ + T+ +V+E+  
Sbjct  644  DASIAWSEEGLEGSRKFLDRVYRLI------TTKEITEENSGALDKVYNETVKAVTEQVD  697

Query  815  ALRNNTAAAKLIEYTNHLTKQHRDGVPRGaveplalmlaplaphlaeelWQRL-GHDSSL  873
             ++ NTA A+L+ + N   K+++  +  +    +  ++AP+APHL+EELWQ L + + S+
Sbjct  698  QMKFNTAIAQLMVFVNAANKEDK--LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESI  755

Query  874  AHGPFPVADPAYLVTDTADYPVQVNGKKRGLVTVAADANTEEIKAAALADEKVQAFLAGA  933
            +  P P  D + LV +  +  VQ++GK ++ + VA D + EE++  ALA+EKVQA +AG 
Sbjct  756  SYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGK  815

Query  934  TPKKVIVVSGRLVNLVV  950
               KVI V+ +LVN+V+
Sbjct  816  DIIKVIAVPNKLVNIVI  832


 Score =  129 bits (472),  Expect = 1e-30, Method: Compositional matrix adjust.
 Identities = 75/148 (51%), Positives = 97/148 (66%), Gaps = 11/148 (7%)

Query  19   IEGAWQDHWERAGTFNVANPVGSLAPSDGAAIPADKMFVQDMFPYPSGDGLHVGHPLGYI  78
            IE  WQ  W    TF+            G+  +  K +  DMFPYPSG GLHVGHP GY 
Sbjct  9    IEPKWQAFWADNHTFKT-----------GTDASKPKFYALDMFPYPSGAGLHVGHPEGYT  57

Query  79   ATDVYARYFRMTGHNVLHALGFDAFGLPAEQYAVQTGTHPRIRTEANIENFRRQLRRLGL  138
            ATD+ +R+ R  GHNVLH++G DAFGLPAEQYA++TG +P   T  NI NF+RQ+  LG+
Sbjct  58   ATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGF  117

Query  139  GHDSRRSFSTTDVDFYKWTQWIFLQIYN  166
            + D  R  +TTD ++YKWTQWIF ++Y+
Sbjct  118  SYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1750) leuS in NC_013235


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  462 bits (1741),  Expect = 5e-131, Method: Compositional matrix adjust.
 Identities = 333/749 (45%), Positives = 485/749 (65%), Gaps = 68/749 (9%)

Query  232  LAYIDEAPVNWCPGLGTVLSNEEVTADGRSAIGNYPVFRRSLRQWMMRITAYAdrllddl  291
            LAY  E PVNW   LGT ++NEEV +DG S  G YPV R+++RQWM++ITAYA+RLL+DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  292  drldWPESVKSMQRNWIGRSYGATVSFPVASRETSREGLPDNGSGSDMAGIEVYTTRPDT  351
            + +DWPES+K MQRNWIG+S GA V+F V  ++T ++             + V+TTRPDT
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKV--KDTDKD-------------FTVFTTRPDT  252

Query  352  LFGATYMVLAPEHPLVESITATRWPRGTDPRWTGGADTPAQAIAEYRLAASRKSDLDRQE  411
            LFGATY VLAPEH+LV++IT++                 A+A+A+Y+  AS KSDL R +
Sbjct  253  LFGATYAVLAPEHALVDAITTS---------------DQAEAVADYKRQASLKSDLARTD  297

Query  412  -NKDKTGVFTGAYATNPATGTDLPIFIADYVLMGYGTGAIMAVPAEDTRDFDFATAFGLP  470
              K+KTGV TG+YA NP  G ++P+ IADYVL +YGTGAIMAVPA+D RD +FA  F L 
Sbjct  298  LAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLD  357

Query  471  IVRTVQPPADHPEDQAYTGDGPTINSANDEISLNGLDVVAAKAAIIDWLTAKGVGQARKQ  530
            I+  ++  +++ E+ A+T DG  INS      L+GLD  +A A +++WL A GVG+    
Sbjct  358  IIPVLE--GGNVEEAAFTEDGLHINSD----FLDGLDKASAIAKMVEWLEAEGVGNENVT  411

Query  531  YKLRDWLFSRQRYWGEPFPIVYDEHGVAISlpdellpltlpeVSDYSPQSFDPQDATSQP  590
            Y+LRDWLFSRQRYWGEP+PI+  E+G + ++P+  LPL LP   D  P        ++  
Sbjct  412  YRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTG  463

Query  591  VPPLARATEWATVELDLGDGPKTYTRELNVMPQWAGSCWYELRYLDPTNDKTFCDPEVER  650
             +PLA  T+W  +E+   DG K   RE N MPQWAGS WY LRY+DP N   + D E+ +
Sbjct  464  ESPLANVTDW--LEVTREDGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLK  520

Query  651  YWMGKNPDRPNDPGGVDLYVGGVEHAVLHLLYSRFWHKVLFDLGHVSSEEPYRKLFNQGY  710
             W+            VD+YVGG EHAVLHLLY+RFWHKVL+DLG V++ EP++KLFNQG 
Sbjct  521  QWL-----------PVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGM  569

Query  711  IQAYAYTDERGLYVPADEVTEVAPEKFEYQ-GRPVTREYGKMGKSLNNVVTPDEMCERFG  769
            I + +Y D RG  V++D V       F+ + G  + +  +KM+KSL+NVV PD++ E++G
Sbjct  570  ILGTSYRDSRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYG  629

Query  770  ADTFRMYEMGMGPMDMSRPWQTRDVVGSQRYLQRLWRLVVDESTGDTVVADAEPDLQTQR  829
            ADT+R+YEM MGP+D S +W   ++ GS+++L+R+ RL+    T   +  +    L  ++
Sbjct  630  ADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLI----TTKEITEENSGAL--DK  683

Query  830  LLHRTIDGVRADYAAMGYNTAIAKLIVLTNHLTKSGAPVPRTVAEALVLMTAPLAPHIAE  889
            + + T+ +V  +   M +NTAIA+L+V+ N   K +   +   A ++V + AP+APH++E
Sbjct  684  VYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFS-DYAKGFVQLIAPFAPHLGE  742

Query  890  EMWARL-GHSRSLAHGPFPEADPALLVAEQVEYPIQVKGKVRGRITIDataavsaieaaa  948
            E+W  L + + S++  P P  D + LV ++VE  +Q+KGKV++++ +    +   ++  A
Sbjct  743  ELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVA  802

Query  949  laEPRIVELLAGATPRKVVVVPGKMVSIV  977
            LA+ ++   +AG    KV+ VP K+V+IV
Sbjct  803  LANEKVQAEIAGKDIIKVIAVPNKLVNIV  831


 Score =  143 bits (526),  Expect = 6e-35, Method: Compositional matrix adjust.
 Identities = 78/150 (52%), Positives = 105/150 (70%), Gaps = 11/150 (7%)

Query  33   ADIEQRWQDRWEAEGTFQAPNPAGPLAPADGSPVPKDKLYLLDMFPYPSGAGLHVGHPLG  92
            + IE +WQ  W  + TF++           G+  +K K+Y LDMFPYPSGAGLHVGHP G
Sbjct  7    TAIEPKWQAFWADNHTFKT-----------GTDASKPKFYALDMFPYPSGAGLHVGHPEG  55

Query  93   YIGTDVIGRFMRMTGRNVLHTIGYDAFGLPAEQYAVRTGTHPRTTTEANITRYRAQLRRL  152
            Y +TD+++RF R  G+NVLH +G DAFGLPAEQYA+ TG +P   T  NI+ ++ Q+  L
Sbjct  56   YTATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINAL  115

Query  153  GFAHDQRRSVATTDPEFFRWTQWIFTQLFE  182
            GF+ D  R V TTDP++++WTQWIFT+L+E
Sbjct  116  GFSYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1751) leuS in NC_016109


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  461 bits (1736),  Expect = 1e-130, Method: Compositional matrix adjust.
 Identities = 350/742 (48%), Positives = 482/742 (65%), Gaps = 64/742 (8%)

Query  224  LAYSKEVPVNWCPGLGTVLANEEVTADGRSERGNFPVFKSNLRQWMMRITAYAdrliddl  283
            LAY  EVPVNW   LGT +ANEEV +DG SERG +PV +  +RQWM++ITAYA+RL++DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  284  dlldWPEAIKLQQRNWIGRSEGARVDFT--AGGDTVTVFTTRPDTLFGATYMVLAPEHAL  341
            + +DWPE+IK  QRNWIG+S GA V F     +   TVFTTRPDTLFGATY VLAPEHAL
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  342  VDTVVPAEWPAGTREEWTGGaanpadavaayraaaaaKSDVERQADAKVKTGVFTGAFAT  401
            VD++  ++ + +  +               Y+  A+ KSD+ R   AK KTGV TG++A 
Sbjct  268  VDAITTSDQAEAVAD---------------YKRQASLKSDLARTDLAKEKTGVWTGSYAI  312

Query  402  NPVSGEQIPVFIADYVLMGYGTGAIMAVPAHDSRDFAFARAFNLPMRCVVQPTDGRGEDP  461
            NPV+G ++PV IADYVL +YGTGAIMAVPAHD RD  FA+ FNL +  V++  +      
Sbjct  313  NPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVE----  368

Query  462  QDWDDAFDTYDSVLVNSEREGLSLNGLSVVDAKARVTAWLGERGIGEGTVNYRLRDWLFS  521
               + AF   D++ +NS+     L+GL    A A++  WL   G+G+  V YRLRDWLFS
Sbjct  369  ---EAAFTE-DGLHINSD----FLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  522  RQRYWGEPFPIVYDETGAMHALPESMLPVEVPEVEDYSPHTYDPDDAASSPKTPLSRNED  581
            RQRYWGEP+PI+  E G+  A+PES LP+ +P   D  P        +++  +PL+   D
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTD  472

Query  582  WVNVELDLGDGVKTYRRETNTMPNWAGSCWYELRYVDPVNSTSVVDPANEAYWMGPTAEK  641
            W++V  +  DGVK  RRETNTMP+WAGS WY LRY+DP N+  + D      W+      
Sbjct  473  WLEVTRE--DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLP-----  524

Query  642  PAGGVDLYVGGAEHAVLHLLYARFWHKVLHDLGHVSSVEPFHKLFNQGMITADVYRDARG  701
                VD+YVGGAEHAVLHLLYARFWHKVL DLG V++ EPF+KLFNQGMI +  YRD+RG
Sbjct  525  ----VDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRG  580

Query  702  FPVPAAEVEDPQGNGQYVWQGEPVRREAGKMGKSLKNAVAPDEIADEYGADTLRLYEMAM  761
              V++  VE  +G+   V  GE + + ++KM+KSLKN V PD++ ++YGADTLR+YEM M
Sbjct  581  ALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFM  640

Query  762  GPLDVSRPWDTRAVVGSYRFLQRLWRNIvsevtgelvvteeePDEATL-RALHKTIDGIR  820
            GPLD S +W   ++ GS +FL+R+ R I             E + ++L +  + T+ ++ 
Sbjct  641  GPLDASIAWSEEGLEGSRKFLDRVYRLI-------TTKEITEENSGALDKVYNETVKAVT  693

Query  821  GDMAGMRFNTAVAKAIELNNFLVKRGSTPRSVAEW---IVLLVAPLAPHIAEELWRRL-G  876
             ++  M+FNTA+A   +L  F+       +  ++    +V L+AP+APH++EELW+ L +
Sbjct  694  EQVDQMKFNTAIA---QLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTA  750

Query  877  HEESLAFADYPVADPAYLVDDTVTCVVQIKGKVKARLEVPPSISdaelealaladpavva  936
              ES+++   P  D + LV++ V  VVQIKGKVKA+L V+  +S  EL+ +ALA+  V A
Sbjct  751  SGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQA  810

Query  937  avggaevRKVIARAPKLVNIVT  958
             ++G ++ KVIA + KLVNIV 
Sbjct  811  EIAGKDIIKVIAVPNKLVNIVI  832


 Score =  137 bits (503),  Expect = 4e-33, Method: Compositional matrix adjust.
 Identities = 75/150 (50%), Positives = 106/150 (71%), Gaps = 10/150 (6%)

Query  26   AEIESRWQDLWEKEGTFDAPNPTGPLADGSPVAAKPHSFIMDMFPYPSGAGLHVGHPLGY  85
            + IE++WQ +W  + TF +          +  A+KP  + +DMFPYPSGAGLHVGHP GY
Sbjct  7    TAIEPKWQAFWADNHTFKT----------GTDASKPKFYALDMFPYPSGAGLHVGHPEGY  56

Query  86   IATDVYARFQRMNGYNVLHTLGYDAFGLPAEQYAVQHGVHPRVSTEDNIANMRRQLRRLG  145
             ATD+ +RF+R +G NVLH +G DAFGLPAEQYA++ G +P   T +NIAN +RQ+  LG
Sbjct  57   TATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALG  116

Query  146  LGHDSRRSISTIDPEYYRWTQWIFLQIFNS  175
            ++ D  R ++T DP+YY+WTQWIF ++++ 
Sbjct  117  FSYDWDREVNTTDPNYYKWTQWIFTKLYEK  146

1752) FB2170_07704 in NC_014472


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  461 bits (1737),  Expect = 1e-130, Method: Compositional matrix adjust.
 Identities = 297/735 (41%), Positives = 465/735 (64%), Gaps = 54/735 (7%)

Query  205  LTYLAETEVNWCPALGTVLANDEIV-NGVSERGGHPVVRKKMTQWSMRITAYAQRLLDGL  263
            L+Y AE  VNW   LGT +AN+E++ +G SERGG PVVRK M QW ++ITAYA+RLL++L
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  264  DKIYWPQPLKDSQTNWIGRSEGASAIFNVNGHDAIIDVFTTRPDTIFGVSFMTLAPEHEL  323
            + + WP+++KD Q NWIG+S GA+  F+V++ D  + VFTTRPDT+FG ++  LAPEH L
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  324  VSKITTGEQKAEVEAYIEATAKRSERDRMADVKTITGAFTGAYAEHPFTKEPIPIWIGDY  383
            V  ITT++Q   V  Y   ++ +S+  R    K  TG  TG+YA +P     +P+WI+DY
Sbjct  268  VDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAINPVNGKEMPVWIADY  327

Query  384  VLAGYGTGAVMSVPCGDQRDYDFAKHFNISIPNIFEGVDISEEAFADKSTTVITNSDFLN  443
            VLA+YGTGA+M+VP  D+RD +FAK+FN+ I  ++EG ++ E AF++ +  +  NSDFL+
Sbjct  328  VLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEAAFTEDGLHI--NSDFLD  385

Query  444  GLKYTKAVKRAIYELAQLGQGEGKINYRLRDAVFSRQRYWGEPFPVYY-VDGMPQMINAE  502
            GL  + A+ + +  L   G G+ ++ YRLRD +FSRQRYWGEP+P+    DG +  +   
Sbjct  386  GLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPES  445

Query  503  HLPIELPEVEKYLPTETGEPPLGNAEVWAWDTDTNKVVHNSAINNATVWPLELNTMPGWA  562
            +LP+ LP      P+ TGE+PL+N   W        V ++ +++       E NTMP WA
Sbjct  446  ELPLVLPVTKDIRPSGTGESPLANVTDWL------EVTREDGVKGRR----ETNTMPQWA  495

Query  563  GSSQYFNRYMDSGNENDIFSKEAINYWQDVDLYIGGSEHATGHLLYSRFWQKFMFDKGLV  622
            GSS Y+ RY+D+ N + +   E ++ W  VD+Y+GG+EHA  HLLY+RFW+K ++D G+V
Sbjct  496  GSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVV  555

Query  623  PKDEFAKKLINQGMITGTSAFVYREEETGNVISKGLIEGKKVTPIHADVSLINTSDELNI  682
            P  E  +KL+NQGMI GTS   YR +  G +++ + +E +  + +H     ++T++EL+ 
Sbjct  556  PTKEPFQKLFNQGMILGTS---YR-DSRGALVATDKVEKRDGSFFH-----VETGEELE-  605

Query  683  EGFKKWLPEYKATEFVLEDGKYVVGREVEKMSKSKYNVVSPDSICEDYGADSLRLYEMFL  742
                                     +   KMSKS  NVV+PD + E+YGAD+LR+YEMF+
Sbjct  606  -------------------------QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFM  640

Query  743  GPLEQSKPWNTAGISGTHSFLKKLWRLYFDENGAKFTNAEPTKDNLKTLHKTIKKVEEDI  802
            GPL+ S +W+  G+ G++ FL ++ RL      +K    E +    K  + T+K V E++
Sbjct  641  GPLDASIAWSEEGLEGSRKFLDRVYRLI----TTKEITEENSGALDKVYNETVKAVTEQV  696

Query  803  ENFSFNTSVSTFMICVNELISQKCTSRAILEPLAILVSPYAPHIAEELWEQL-GHDESIA  861
            ++  FNT+++ +M+ VN    +          +  L++P+APH++EELW+ L + +ESI+
Sbjct  697  DQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESIS  756

Query  862  TVSFPIFDGSHLVESTKQYPISFNGKMRFTLELPLDMGKDEIEETVMAHEKTQQQLQGRT  921
             V+ P +D S LVE+  +  + ++GK++  L ++ D++++E++E  +A+EK Q ++ G+ 
Sbjct  757  YVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKD  816

Query  922  PKKIIVVPGKIVNIV  936
              K+I VP K+VNIV
Sbjct  817  IIKVIAVPNKLVNIV  831


 Score =  179 bits (664),  Expect = 7e-46, Method: Compositional matrix adjust.
 Identities = 86/142 (61%), Positives = 115/142 (81%), Gaps = 0/142 (0%)

Query  3    YNFNEIEAKWQKYWAKNQTFKAENNSEKEKFYVLDMFPYPSGAGLHVGHPLGYIASDIYA  62
            Y+   IE+KWQ +WA N+TFK+  ++ K KFY LDMFPYPSGAGLHVGHP GY A+DI +
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRHKGFNVLHPMGYDSFGLPAEQYAIQTGQHPAITTETNINRYREQLDKIGFSFDWSR  122
            R+KR +G NVLHPMG D+FGLPAEQYA++TG++PA  T  NI  ++ Q++ +GFS+DW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVRTSNPKYYKWTQWVFIQLFN  144
            EV T++P+YYKWTQW+F +L++
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYE  145

1753) leuS in NC_013062


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  461 bits (1739),  Expect = 7e-131, Method: Compositional matrix adjust.
 Identities = 302/721 (42%), Positives = 465/721 (65%), Gaps = 55/721 (7%)

Query  204  LAFRAETTVNWCPGLGTVLANDEV-KDGKSERGGFPVFQKKMMQWSMRITAYSERLLQGL  262
            LA+ AE  VNW   LGT +AN+EV  DG SERGG+PV +K M QW ++ITAY+ERLL++L
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  263  QNIDWPQPLKDAQEYWIGKSQGAQVTFGLDNGTEQITVFTTRPDTIFGATFMVLAPENPL  322
            +++DWP+++KD Q  WIGKS GA+VTF + +   ++TVFTTRPDT+FGAT+ VLAPE++L
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  323  VETITTPNQKEEVENYIQETSKKTERDRMADVKNVSGAFTGAYAVNPFTHEKMPVYISDY  382
            V++ITT++Q E V +Y +++S K++  R    K+ +G  TG+YA+NP     MPV I+DY
Sbjct  268  VDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAINPVNGKEMPVWIADY  327

Query  383  VLMGYGTGAVMAVPAHDERDHRFAKKFALPILNVIKNDEDINETSYDSKNSVCVNSGFLD  442
            VL +YGTGA+MAVPAHDERD  FAK+F L I+ V+ ++ +++E+++ + +++ +NS+FLD
Sbjct  328  VLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL-EGGNVEEAAF-TEDGLHINSDFLD  385

Query  443  GLNYTEAKAKIISEIEKLGIGRGTTNYRQRDAIFSRQRYWGEPVP-VYYKDGMPYPLPVS  501
            GL+ + A AK++  +E  G+G     YR RD +FSRQRYWGEP+P +   DG + ++P S
Sbjct  386  GLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPES  445

Query  502  ALPLELPEVEKYLPTEDGDPPLGNAKNFGWDEKNEKVVATELIDEKSVFALELSTMPGWA  561
             LPL LP      P+  G++PL+N  +  W E    V   + +  +     E +TMP WA
Sbjct  446  ELPLVLPVTKDIRPSGTGESPLANVTD--WLE----VTREDGVKGRR----ETNTMPQWA  495

Query  562  GSSWYFLRYMDPHNDEVFAQKELTDYWGQVDLYIGGSEHATGHLLYSRFWNMFLKDRGYV  621
            GSSWY+LRY+DPHN E +A+ EL   W  VD+Y+GG+EHA  HLLY+RFW+  L D G V
Sbjct  496  GSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVV  555

Query  622  QHDEPFKKLINQGMILGMSAYVFRIEGTNQFISKNLIQDHTTQKIHVDVSLLKGTSDELD  681
               EPF+KL+NQGMILG S   +R ++   +++ + ++ +    +HV+      T++EL 
Sbjct  556  PTKEPFQKLFNQGMILGTS---YR-DSRGALVATDKVEKRDGSFFHVE------TGEEL-  604

Query  682  IERFKNWRSEYADAEFILEDGKYITEREVEKMSKSKYNVVNPDDICEEYGADCLRLYEMF  741
                                     E+   KMSKS  NVVNPDD+ E+YGAD LR+YEMF
Sbjct  605  -------------------------EQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMF  639

Query  742  LGPLEQSKPWNTQGLSGVYGFLKKFYNLYFNGDQFEVSDEEPTKEEYKILHTLIRKVVSD  801
            +GPL+ S +W+ +GL G   FL + Y L       E+++E++   + K+ +  ++ V  +
Sbjct  640  MGPLDASIAWSEEGLEGSRKFLDRVYRLITTK---EITEENSGALD-KVYNETVKAVTEQ  695

Query  802  IANFSFNTSVSSFMIAVNEYQKLKTNKRQILEAMAVIVSPYAPHLCEELWSRLGHNS-TV  860
            + +  FNT+++ +M+ VN  +K      +   +   +++P+APHL EELW  L  ++ ++
Sbjct  696  VDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESI  755

Query  861  ELEKFPEFDEKYLVEDEFEYPVSFNGKMRFKLSLPADYTVSEIEESVMKDQRVINQLAGN  920
                 P +DE  LVE++ E  V ++GK++ KL ++ D +  E++E  + +++V  ++AG+
Sbjct  756  SYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGK  815

Query  921  S  921
             
Sbjct  816  D  816


 Score =  184 bits (683),  Expect = 2e-47, Method: Compositional matrix adjust.
 Identities = 90/143 (63%), Positives = 116/143 (82%), Gaps = 0/143 (0%)

Query  2    FYDHQSIEKKWQKFWKENQTFKTEDNTQKPKYYVLDMFPYPSGAGLHVGHPLGYIASDIY  61
            FYDH +IE KWQ FW +N+TFKT  ++ KPK+Y LDMFPYPSGAGLHVGHP GY A+DI 
Sbjct  3    FYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDIL  62

Query  62   ARYKRHEGYNVLHPVGYDSFGLPAEQYAIQTGTHPAITTEQNITRYEEQLRKIGFSFDWS  121
            +R+KR +G NVLHP+G D+FGLPAEQYA++TG +PA  T +NI+ +  Q+  +GFS+DW 
Sbjct  63   SRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWD  122

Query  122  REVRTSDSSYYKWTQWIFIELFN  144
            REV T+D++YYKWTQWIF  L++
Sbjct  123  REVNTTDPNYYKWTQWIFTKLYE  145

1754) leuS in NC_007777


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  459 bits (1728),  Expect = 7e-130, Method: Compositional matrix adjust.
 Identities = 342/787 (44%), Positives = 486/787 (62%), Gaps = 105/787 (13%)

Query  280   LAYISEQLVNWCPGLGTVLANEEVTADGRSDIGNYPVFRRPLKQWILRITAYAERLISDL  339
             LAY +E  VNW   LGT +ANEEV +DG S+ G YPV R+P++QW+L+ITAYAERL+ DL
Sbjct  148   LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  340   DLVDWPDSIKQMQRNWISPSEGASVEFTVVAPGEEAGASDPSGSSTARRIEVYTTRPDTL  399
             + VDWP+SIK+MQRNWI+ S GA+V F V                T + + V+TTRPDTL
Sbjct  208   EEVDWPESIKDMQRNWIGKSTGANVTFKV--------------KDTDKDFTVFTTRPDTL  253

Query  400   AGATFLVLAPEHPLADALIADTWPADTPVSWRFPAGRPGGGTEPADTAGPEAGADPAWTP  459
              GAT+ VLAPEH+L DA+ +                     ++ A+              
Sbjct  254   FGATYAVLAPEHALVDAITT---------------------SDQAE--------------  278

Query  460   RAAVDAYREFAAHRSDRQRGEEVIDRTGVFTGSYVRNPVGGGVIPVFLADYVLLGYGTGA  519
               AV  Y+  A+ +SD  R +   ++TGV TGSY  NPV G  +PV +ADYVL +YGTGA
Sbjct  279   --AVADYKRQASLKSDLARTDLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGA  336

Query  520   IMAVPAHDSRDFSFARAFDLPIPAVLEPDADWYAAHGVVPATPSAQWPEAFSGAGEYRPG  579
             IMAVPAHD RD  FA+ F+L I +VLE         G V  ++ ++  +++   +++   
Sbjct  337   IMAVPAHDERDWEFAKQFNLDIIPVLEG--------GNVEEAAFTE--DGLHINSDF---  383

Query  580   PASAPVLVGLSKSEAIKATVHWLEEIGAGRSARSYRLRDWLFSRQRYWGEPFPIVFDVDG  639
                   L GL K+ AI   V+WLE  G G    +YRLRDWLFSRQRYWGEP+PI+   DG
Sbjct  384   ------LDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDG  437

Query  640   LPHAVPDELLPIELPEMTDFRPTAMAEDDASDPVPPLARVADWVTVTLDLGDGPKQYRRE  699
              + AVP+  LP+ LP   D+RP++ +E       +PLA V+DW+ VT +  DG K  RRE
Sbjct  438   TSTAVPESELPLVLPVTKDIRPSGTGE-------SPLANVTDWLEVTRE--DGVKG-RRE  487

Query  700   TNTMPQWAGSCWYYLRYLDPTNTERFVDPTVERYWMARPGAvpgdggvdlyvggvEHAVL  759
             TNTMPQWAGS WYYLRY+DP NTE++ D  + + W++          VD+YVGG EHAVL
Sbjct  488   TNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLP----------VDIYVGGAEHAVL  537

Query  760   HLLYARFWHKVLYDLGHVSTKEPFKRLFNQGYIQADAFTDARGMYVPAAEVTATPDGRFL  819
             HLLYARFWHKVLYDLG V+TKEPF++LFNQG I + ++ D+RG  V++  V    DG F 
Sbjct  538   HLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKV-EKRDGSF-  595

Query  820   FQ---GAPVNRRSGKMGKSLKNSVSPDEMYDRFGADTLRVYEMAMGPLDADRPWHTDDIV  876
             F+   G  +++ ++KM+KSLKN V+PD++ +++GADTLRVYEM MGPLDA  +W  +++ 
Sbjct  596   FHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLE  655

Query  877   GSHRFLQRLWRTVVDETTGAAAVVDEPLDDEALRVLHRTILTVTAEYAGLRFNTAVARLI  936
             GS++FL+R+ R +   T   +     +LD    +V + T+ +VT +   ++FNTA+A+L+
Sbjct  656   GSRKFLDRVYRLIT--TKEITEENSGALD----KVYNETVKAVTEQVDQMKFNTAIAQLM  709

Query  937   ELTNFVSKSYGKSPTPRALAEPLTLMAAPLAPHIAEELWSRL-GHEESVSTVAFPIGDPA  995
                 FV+ +          A  +  + AP+APH++EELW  L +  ES+S V+ P  D +
Sbjct  710   ---VFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDES  766

Query  996   LAAESVRTIPVQVNGKVRFTIEVPDGSAEQTVRDLLAAHPEFARQTDGRTIKKIIVVPGR  1055
                E+   I VQ++GKV+  + V+ + + + ++++  A+     +  G+ I K+I VP +
Sbjct  767   KLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNK  826

Query  1056  IVNIAIS  1062
             +VNI I 
Sbjct  827   LVNIVIK  833


 Score =  141 bits (517),  Expect = 3e-34, Method: Compositional matrix adjust.
 Identities = 75/151 (50%), Positives = 108/151 (72%), Gaps = 11/151 (7%)

Query  61   ADIERRWQRRWADEGTFNSPNPVGPLSTGFEKVAGREPFYIMDMFPYPSGSGLHVGHPLG  120
            + IE +WQ  WAD+ TF++              A++  FY +DMFPYPSG+GLHVGHP G
Sbjct  7    TAIEPKWQAFWADNHTFKTGTD-----------ASKPKFYALDMFPYPSGAGLHVGHPEG  55

Query  121  YIGTDVFARYLRMSGRHVLHPFGYDSFGLPAEQYAINTGQHPRDTTNANIANMRRQLSRL  180
            Y +TD+++R+ R  G++VLHP G D+FGLPAEQYA++TG++P + T  NIAN +RQ++ L
Sbjct  56   YTATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINAL  115

Query  181  GLGHDTRREIATTDVGYYRWTQWIFQQIFNS  211
            G++ D  RE+ TTD  YY+WTQWIF ++++ 
Sbjct  116  GFSYDWDREVNTTDPNYYKWTQWIFTKLYEK  146

1755) Cycma_0967 in NC_015914


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  457 bits (1722),  Expect = 2e-129, Method: Compositional matrix adjust.
 Identities = 297/702 (43%), Positives = 447/702 (64%), Gaps = 46/702 (6%)

Query  206  LTYLAETTVNWCAALGTVLSNDEV-KDGFSERGGHPVERKRMMQWSMRITAYAERLLNGL  264
            L+Y AE  VNW   LGT ++N+EV  DG SERGG PV RK M QW ++ITAYAERLL++L
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  265  ESLDWPDPVKEMQRNWIGRSLGAEMVFDVEGQNEKIKVFTTRIDTIYGVTYLALAPEHEL  324
            E +DWP+++K+MQRNWIG+S GA++ F V + +  + VFTTR DT++G TY  LAPEH L
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  325  VEKLITEDQREIAVSYVAQAKNRSERDRMADVKTISGAFTGSYAKNPFNGESIPIWIADY  384
            V+ + T DQ E    Y  QA  +S+  R    K  +G  TGSYA NP NG  +P+WIADY
Sbjct  268  VDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAINPVNGKEMPVWIADY  327

Query  385  VLAGYGTGAVMAVPSHDERDYNFANHFGLEKRQVIEG-DMSEGSFPGKGGTIMNSGFISG  443
            VLA+YGTGA+MAVP+HDERD +FA++F L+   V+EG ++ E++F   G  I NS+F+ G
Sbjct  328  VLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEAAFTEDGLHI-NSDFLDG  386

Query  444  LKMQEAMDKAIAFLEEKGIGKGKIQYKMRDAIFTRQRYWGEPLP-VYFKNDLPYLVDERD  502
            L    A+ K +  LE  G+G+ ++ Y++RD +F+RQRYWGEP+P +   ++ +  V E +
Sbjct  387  LDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESE  446

Query  503  LPLPLPEVDKYLPTEDGAPPLGRAKDW--TYKTEEGTFPLEMSTMPGWAGSSWYFFRYMD  560
            LPL LP      P+  G +PL+   DW    + +      E +TMP WAGSSWY++RY+D
Sbjct  447  LPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYID  506

Query  561  AQNKEEFVSKSAANYWGSVDLYIGGAEHATGHLLYSRFWTKFLFDRGLVPIEEPFQKMIN  620
            ++N E +      + W +VD+Y+GGAEHA  HLLY+RFW K L+D G+VP  EPFQK++N
Sbjct  507  PHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFN  566

Query  621  QGMIQGRSNFVYRKKGTNIFVSHGLIGEHEVSPMHVDVNIVYNDQLDIEAFRNWRPDLKD  680
            QGMI G S   YR  +   +V+ + +  ++ S  HV+      ++L+  +          
Sbjct  567  QGMILGTS---YR-DSRGALVATDKVEKRDGSFFHVET----GEELEQAP----------  608

Query  681  AEFILEDGKYNCGAEVEKMSKSKYNVVNPDDVIESYGADTLRLYEMFLGPLEQFKPWNTN  740
                             KMSKS  NVVNPDDV+E YGADTLR+YEMF+GPL+   +W+ +
Sbjct  609  ----------------AKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEE  652

Query  741  GIDGVFKFLKKLWRLFHDKDGKWNVSDKPASKEALKSLHKTMKKVEEDIERHAFNTSVSS  800
            G++G  KFL ++ RL+  K+      +++++ +  K  + T+K V E++++  FNT+++ 
Sbjct  653  GLEGSRKFLDRVYRLITTKE---ITEENSGALD--KVYNETVKAVTEQVDQMKFNTAIAQ  707

Query  801  FMICVNELSALKCNNREVLEPLLIVLSPYAPHISEELWE-LLGHEQSIIHAQFPIAEEKY  859
            +M+ VN  +       +    ++ +++P+APH++EELW+ L +  +SI     P  +E  
Sbjct  708  LMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESK  767

Query  860  LTEDSHQYPVSINGKMRAKIELSLSLSKQEIEEAALQDEQIQ  901
            L E+  +  V I+GK++AK+ ++  LS++E++E AL +E++Q
Sbjct  768  LVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQ  809


 Score =  173 bits (642),  Expect = 4e-44, Method: Compositional matrix adjust.
 Identities = 86/145 (60%), Positives = 118/145 (82%), Gaps = 0/145 (0%)

Query  1    MSDYNFRAIEKKWQDRWEQTGIFNASPETNKPKFYSLDMFPYPSGAGLHVGHPLGYIASD  60
            M+ Y+  AIE KWQ  W +   F+++ +++KPKFY+LDMFPYPSGAGLHVGHP GY A+D
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   IVTRYKRLKGFNVLHPMGYDSFGLPAEQYAIQTGQHPAITTEENIKRYTEQLKNIGFAFD  120
            I++R+KR +G NVLHPMG D+FGLPAEQYA++TG++PA  T ENI  +  Q++ +GF++D
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WSKEVRTSDPEYYRWTQWIFMQLFE  145
            W +EV T+DP+YY+WTQWIF +L+E
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYE  145

1756) Bacsa_2284 in NC_015164


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  456 bits (1717),  Expect = 4e-129, Method: Compositional matrix adjust.
 Identities = 313/729 (43%), Positives = 454/729 (63%), Gaps = 66/729 (9%)

Query  204  IAYLGETMVNWCPQLGTVLANDEVV-DGVSERGGYPVVQKKMRQWCLRVSAYAGRLLDGL  262
            +AY +E  VNW  +LGT +AN+EV+ DG SERGGYPVV+K MRQW L+++AYA RLL++L
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  263  DHIDWTDSLKETQRNWIGRSEGTEVRFKVKDRDLEFTIFTTRADTMFGVTFMVLAPESEL  322
            +++DW +S+K+ QRNWIG+S G++V FKVKD D +FT+FTTR+DT+FG T+ VLAPE  L
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  323  VPQVTTDGQRAEVEAYLDRTKKRTERERIA-DRRVTGVFSGSYAINPFTGDAVPIWISDY  381
            V  +TT +Q   V  Y  ++  +++  R    +  TGV +GSYAINP  G  +P+WI+DY
Sbjct  268  VDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAINPVNGKEMPVWIADY  327

Query  382  VLAGYGTGAIMAVPAHDSRDYAFAKHFNLPIVPLVEGCDVSEESFDAKEGIVCNSPKAGV  441
            VLA+YGTGAIMAVPAHD RD  FAK+FNL I+P++EG +V E +F + +G+  N      
Sbjct  328  VLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEAAF-TEDGLHIN------  380

Query  442  TPYCDLNLNGLTIKEAIAATKEYVKAHHLGRVKVNYRLRDAIFSRQRYWGEPFPVYY-KD  500
                D+ L+GL    AIA   E + A+ +G  +V YRLRD +FSRQRYWGEP+P+    D
Sbjct  381  ---SDF-LDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWED  436

Query  501  GMPYMIDENKLPLELPEVDKFLPTETGEPPLGHATKWAWDVEKGEVVENTKIDNVHVFPL  560
            G +  + E+ LPL LP    + P+ TGE+PL++ T W  +V + + V   +         
Sbjct  437  GTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWL-EVTREDGVKGRR---------  486

Query  561  ELNTMPGFAGSSAYYLRYMDPHNDKALVSEKADRYWQNVDLYVGGTEHATGHLIYSRFWN  620
            E NTMP  AGSS YYLRY+DPHN   L  E   + W  VD+YVGG+EHA  HL+Y+RFW+
Sbjct  487  ETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWH  546

Query  621  KFLFDLGVSVKEEPFQKLVNQGMIQGRSNFVYRIKDTNTFVSLGLKDQYDVTPLHVDVNI  680
            K L+DLGV    EPFQKL NQGMI G S   YR     ++V+ +  ++ D + +HV+   
Sbjct  547  KVLYDLGVVPTKEPFQKLFNQGMILGTS---YR-DSRGALVATDKVEKRDGSFFHVE---  599

Query  681  VTNDVLDIEAFKNWRPEYHDAEFILEDGKYICGWAVEKMSKSMYNVVNPDMIVEKYGADT  740
             T + L+  +                           KMSKS+ NVVNPD +VE+YGADT
Sbjct  600  -TGEELEQAP--------------------------AKMSKSLKNVVNPDDVVEQYGADT  632

Query  741  LRMYEMFLGPVEQSKPWDTNGIDGVHRFLKKLWNLFYGRQGEFLPTESEATKEELKSI-H  799
            LR+YEMF+GP++ S +W  +G++G ++FL ++  L+  ++       +E     L  + +
Sbjct  633  LRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKE------ITEENSGALDKVYN  686

Query  800  KLIKKVTGDIEVFSYNTSISAFMICVNELTALKSRNKAVLTDLVILLAPFAPHLAEELWE  859
              +K VT +++   +NT+I+ +M+ VN              ++V L+APFAPHL+EELW+
Sbjct  687  ETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  860  AL-GHGTTVCDAQWPAWNEDYLKEDTVKYTISFNGKARFTMEFPADADNDTIQAAVMAEE  918
            AL + G ++    WP+ +E  L E+ V   + ++GK +  +  + D   + +Q   +A+E
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  919  QSQKWIEGK  927
            + Q  I GK
Sbjct  807  KVQAEIAGK  815


 Score =  153 bits (564),  Expect = 6e-38, Method: Compositional matrix adjust.
 Identities = 77/124 (63%), Positives = 100/124 (81%), Gaps = 0/124 (0%)

Query  21   TYQVTEDESKQKFYVLNMFPYPSGAGLHVGHPLGYIASDIYARYKRLQGFNVLNPMGYDA  80
            T++   D SK KFY L+MFPYPSGAGLHVGHP GY A+DI +R+KR QG NVL+PMG DA
Sbjct  22   TFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSRFKRAQGHNVLHPMGWDA  81

Query  81   YGLPAEQYAIQTGQHPAITTQNNINRYREQLDKIGFSFDWDREVRTCDPKYYHWTQWAFQ  140
            +GLPAEQYA++TG++PA  T +NI  ++ Q++ +GFS+DWDREV T DP+YY WTQW F 
Sbjct  82   FGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFT  141

Query  141  KMFN  144
            K+++
Sbjct  142  KLYE  145

1757) leuS in NC_013132


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  456 bits (1717),  Expect = 4e-129, Method: Compositional matrix adjust.
 Identities = 308/728 (43%), Positives = 472/728 (65%), Gaps = 52/728 (7%)

Query  204  LAFLAFAEVNWCAALGTVLANDEVI-NGVSERGGFPVVKKKMRQWFLRITEYANRLLEGL  262
            LA+ A   VNW   LGT +AN+EV+ +G SERGG+PVV+K MRQW L+IT YA+RLLE+L
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  263  ETVSFSDAMKEMQRNWIGKSQGAEITFQIDGVENAGVTVYTTRPDTIFGVDFMVLAPEHD  322
            E V  ++++K+MQRNWIGKS GA++TF++ + ++ + TV+TTRPDT+FG  + VLAPEH 
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDK-DFTVFTTRPDTLFGATYAVLAPEHA  266

Query  323  LVSLITTADKKEDVEKYLDYVQSRSERERMAEVKQITGCFTGAYVLNPFNGQRIPVWISE  382
            LV  ITT+D+ E V  Y      +S+  R    K+ TG  TG+Y +NP NG+ +PVWI++
Sbjct  267  LVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAINPVNGKEMPVWIAD  326

Query  383  YVLAGYGTGAIMAVPCGDQRDFNFAKHFDIHITNIIGDAFNGEDANATKDATLQNSDFLD  442
            YVLA+YGTGAIMAVP  D+RD +FAK+F+++I  ++ ++ N E+A  T D+   NSDFLD
Sbjct  327  YVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGG-NVEEAAFTEDGLHINSDFLD  385

Query  443  GMNMRDAMDVVIDKVEAMGIGKRQINYKMRDSGFSRQRYWGEPFPIVY-KDGTPYALDEK  501
            G++   A+  +++ +EA G+G+ ++ Y++RD  FSRQRYWGEP+PI+   DGT+ A+ E 
Sbjct  386  GLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPES  445

Query  502  ELPVTLPHVENYKPGEEGEGPLANITDWVNI----DANTRRETNTMPGYAGSSWYFLRYT  557
            ELP+ LP   + +P+  GE+PLAN+TDW+++    + + RRETNTMP  AGSSWY+LRY 
Sbjct  446  ELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYI  505

Query  558  DPKNAEVFADRAATDYWNQVDVYVGGTEHAVGHLLYSRMWTKALYDLGYIGFQEPYKKLI  617
            DP N+E +AD      W  VD+YVGG+EHAV HLLY+R W K LYDLG +  +EP++KL+
Sbjct  506  DPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLF  565

Query  618  NQGMIGGSSRMVYRLRGTNTYVSHGLKDQYETDELHTDVNIVDGLELDIQAFKNWRPANK  677
            NQGMI G+S   YR                   + +  +   D +E            ++
Sbjct  566  NQGMILGTS---YR-------------------DSRGALVATDKVE------------KR  591

Query  678  DAEFILEDGKYICGVVLEKMSKGKYNTVNPDDVVEKFGADTFRMYEMFLGPVEQSKPWDT  737
            D+ F+  +          KMSK+  N VNPDDVVE++GADT+R+YEMF+GP++ S +W  
Sbjct  592  DGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSE  651

Query  738  KGIEGVHRFLKKLWRLFADEQKGIIVNNDAATPEELKALHKTIQKIDADTENFSYNTAVS  797
             G+EG ++FL ++ RL++  +   I ++++++ +  K  + T++ +  + ++  +NTA++
Sbjct  652  EGLEGSRKFLDRVYRLITTKE---ITEENSGALD--KVYNETVKAVTEQVDQMKFNTAIA  706

Query  798  QFMICVNELSSLKCNK--RSVLEPVLILLAPYAPHIAEELWHLLGNTTSILD-TPYPVFD  854
            Q+M+ VN  ++ K +K         + L+AP+APH++EELW+ L  +   +   P P +D
Sbjct  707  QLMVFVN--AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYD  764

Query  855  EKYTKESAFTYPIAVNGKTRTELSFPLDADNAAIEKEVLENEAVQKWIDGKPvkkivivk  914
            E    E+     + ++GK ++ L  + D     ++   L NE VQ  I GK + K++ V 
Sbjct  765  ESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVP  824

Query  915  GRMINLVV  922
             +++N+V+
Sbjct  825  NKLVNIVI  832


 Score =  184 bits (681),  Expect = 3e-47, Method: Compositional matrix adjust.
 Identities = 88/142 (62%), Positives = 122/142 (86%), Gaps = 0/142 (0%)

Query  3    YNFRAIEKKWQARWVETKAYQVSNNSPKPKCYVLDMFPYPSGAGLHVGHPLGYISSDIYA  62
            Y+  AIE KWQA W +  +++ + +++KPK Y LDMFPYPSGAGLHVGHP GY ++DI +
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRLKGFNVLHPMGWDAFGLPAEQYALETGQHPAVTTANNLASFRRQLDNIGFSFDWER  122
            R+KR +G NVLHPMGWDAFGLPAEQYA++TG++PA  TA+N+A+F+RQ++ +GFS+DW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EIKTSDPDYYKWTQWIFLQLFD  144
            E++T+DP+YYKWTQWIF +L++
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYE  145

1758) leuS in NC_016943


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  455 bits (1715),  Expect = 6e-129, Method: Compositional matrix adjust.
 Identities = 349/740 (48%), Positives = 495/740 (67%), Gaps = 63/740 (8%)

Query  236  LAYLHEAPVNWCPGLGTVLSNEEVTPDGRSERGNFPVFRRPLKQWMMRITAYAdrllddl  295
            LAY  E PVNW   LGT ++NEEV PDG SERG +PV R+P++QWM++ITAYA+RLL+DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  296  drldwsdslklMQRNWIGRSTGARIRFVT--GDETIEVFTTRPDTLFGATYMVLAPEHPL  353
            + +DW++S+K MQRNWIG+STGA + F     D  + VFTTRPDTLFGATY VLAPEH+L
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  354  VDALTASAWPEGADPRWTGGAATPADAVRAYQRQASRRSELDRQDAGREKTGVWLGVTAV  413
            VDA+T+S                 A+AV  Y+RQAS +S+L R D ++EKTGVW G  A+
Sbjct  268  VDAITTSD---------------QAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAI  312

Query  414  NPVNGRELPVFIADYVLTGYGTGAIMAVPGEDQRDWDFARAFGLDVVPTVERPAGFDDSS  473
            NPVNG+E+PV IADYVL++YGTGAIMAVP++D+RDW+FA+ F LD++P +E   G +   
Sbjct  313  NPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE---GGNVEE  369

Query  474  GAYTGPGRMINSSNDEISLDGLDKATAIATVTDWLVRRGAGEATTTYKLRDWLFSRQRYW  533
            +A+T  G  INS      LDGLDKA+AIA + +WL   G G+   TY+LRDWLFSRQRYW
Sbjct  370  AAFTEDGLHINSD----FLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYW  425

Query  534  GEPFPIVYDANDRPVAVPESMLPVLLPEVDDYSPKTFsdddadsaPEPPLSRATEWTTVE  593
            GEP+PI+   ++ + AVPES LP++LP   D  P          + E+PL+  T+W  +E
Sbjct  426  GEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSG--------TGESPLANVTDW--LE  475

Query  594  LDLGDGVQEYRRETNTMPNWAGSCWYYLRYLDPGDDTQMVDPELERYWMGPRgegdvggv  653
            +   DGV+  RRETNTMP+WAGS WYYLRY+DP +  ++ D EL + W+          V
Sbjct  476  VTREDGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLP---------V  525

Query  654  dlyvggveHAVLHLLYARFWHKVLHDLGYVSSEEPFRRLVNQGYISAYAYTDERGFYVPA  713
            D+YVGG EHAVLHLLYARFWHKVL DLG V++ EPF++L NQG I + +Y D RG  V++
Sbjct  526  DIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVAT  585

Query  714  AEVVEKDGGFFF--EGEPVTREYGKIGKSLKNMVTPDEMIGAYGADTFRVYEMSTGPLEQ  771
              V  +DG+FF    GE + +  +K++KSLKN+V PD+++  YGADT+RVYEM  GPL+ 
Sbjct  586  DKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  772  SRPWETKAVVGSQRLLQRIWRVVVDEETGAVRASDAEPAEETLRTLHKAIDGVRDGYSTL  831
            S +W   ++ GS+++L+R+ R++   E     ++  +      +  + ++ +V +    +
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALD------KVYNETVKAVTEQVDQM  699

Query  832  RFNIAIARITELTNHLTQVFGADTpvpravaeplvllvaplaphlaeelWSRLGHHGST-  890
            +FN AIA++  + N   +    +  +    A  +V L+AP+APHL+EELW  L   G + 
Sbjct  700  KFNTAIAQLMVFVNAANK----EDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESI  755

Query  891  ---AWTPFPEADQRWLVEDTVQVAVQVNGKVRSQVTVPtdadaaaletaaradeKVAGYL  947
               +W ++ E+    LVE+ V++ VQ++GKV++++ V+ D     L+  A A+EKV + +
Sbjct  756  SYVPWPSYDESK---LVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEI  812

Query  948  DGATIRRVVAVPGRLVNFVL  967
             G  I +V+AVP +LVN+V+
Sbjct  813  AGKDIIKVIAVPNKLVNIVI  832


 Score =  132 bits (483),  Expect = 1e-31, Method: Compositional matrix adjust.
 Identities = 78/149 (53%), Positives = 99/149 (67%), Gaps = 11/149 (7%)

Query  30   MELDWQDRWAAEGTFHTPNPVGRLSEGFEKIADRPKYFVMDMFPYPSGAGLHVGHPLGYL  89
            +E  WQ  WA + TF T              A +PK++ +DMFPYPSGAGLHVGHP GY 
Sbjct  9    IEPKWQAFWADNHTFKTGTD-----------ASKPKFYALDMFPYPSGAGLHVGHPEGYT  57

Query  90   GTDVTSRFRRMDGDNVLHPMGYDAFGLPAEQYAVQTGQHPRITTEANIAAIRAQLRRLGV  149
            +TD+ SRF+R +G+NVLHPMG DAFGLPAEQYA++TG++P   T  NIA ++ Q+  LG 
Sbjct  58   ATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGF  117

Query  150  DHDDRRSFATIDPAYYKWTQWIFLQIFGS  178
              D  R   T DP YYKWTQWIF +++  
Sbjct  118  SYDWDREVNTTDPNYYKWTQWIFTKLYEK  146

1759) leuS in NC_008571


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  455 bits (1715),  Expect = 6e-129, Method: Compositional matrix adjust.
 Identities = 302/744 (41%), Positives = 468/744 (63%), Gaps = 79/744 (10%)

Query  205  LTYLAEAEVNWCPQLGTVLANDEIV-NGVSERGGYPVVRKKMTQWSMRISAFSERLLQDL  263
            L+Y AE  VNW  +LGT +AN+E++ +G SERGGYPVVRK M QW ++I+A++ERLL+DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  264  NKIDWTESLKESQRNWIGKSVGAHVDFKIENSKFKIGVFTTRPDTIFGVSFMTLAPEHEL  323
            + +DW ES+K+ QRNWIGKS GA+V FK+ ++   + VFTTRPDT+FG ++  LAPEH L
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  324  VEKITTEDRKEEVQAYIEASAKRSERERMADVKTISGAFTGAYAEHPFTKKPVPIWIGDY  383
            V+ ITT D+ E V  Y   ++ +S+  R    K  +G  TG+YA +P   K +P+WI+DY
Sbjct  268  VDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAINPVNGKEMPVWIADY  327

Query  384  VLAGYGTGAVMAVPCGDQRDHDFARHFDLLIPNIFENVDVSQEAYAGKEGTVIANSDFLS  443
            VLA+YGTGA+MAVP  D+RD +FA++F+L I  ++E  +V + A++  E+ +  NSDFL 
Sbjct  328  VLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEAAFT--EDGLHINSDFLD  385

Query  444  GLEYKEALNKVILELEKTGQGYGKTNYRLRDAVFSRQRYWGEPFPVYY-VNGLPKMIDEK  502
            GL+   A+ K++  LE  G G  +  YRLRD +FSRQRYWGEP+P+    +G +  + E 
Sbjct  386  GLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPES  445

Query  503  YLPLKLPEVEKYLPTETGEPPLGNATDWAWDsknnkvvsnkvLKQSRKLSGQHDEPNSNV  562
             LPL LP      P+ TGE+PL+N TDW              L  +R             
Sbjct  446  ELPLVLPVTKDIRPSGTGESPLANVTDW--------------LEVTRE------------  479

Query  563  TPSAVEGSDDNGIYPLELNTMPGWAGSSWYLFRYMGAGNPDRFVSEEAQKYWENVDLYIG  622
               +V G  +        NTMP WAGSSWY +RY+++ N +++  EE  K W  VD+Y+G
Sbjct  480  --DGVKGRRET-------NTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVG  530

Query  623  GSEHATGHLLYSRFWTKFLYDRGWLTVEEPFKKLINQGMILGTSAFVYRLEGENVFVSKN  682
            G+EHA  HLLY+RFW K LYD G +   EPF+KL+NQGMILGTS   YR ++   +V+ +
Sbjct  531  GAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS---YR-DSRGALVATD  586

Query  683  QINGNNVQPIHADVSLVNSSDELDIEGFKKWRPEFADAKFLTEDGKYIVGREVEKMSKSK  742
            +++  +   +H     V++++EL+                          +   KMSKS 
Sbjct  587  KVEKRDGSFFH-----VETGEELE--------------------------QAPAKMSKSL  615

Query  743  YNVVNPDEICQDYGADTLRMYEMFLGPLEQAKPWNTAGITGVHNFLKKLWKLYYDGEEFF  802
             NVVNPD++ ++YGADTLR+YEMF+GPL+ + +W+  G+ G ++FL ++ +L    E   
Sbjct  616  KNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKE---  672

Query  803  VSDEKASADSLKTFHKTIKKVTEDIEEFSFNTSVSTFMICVNELTAQKCNSREILEPLAV  862
            +++E+++A   K ++ T+K VTE++++  FNT+++ +M+ VN    +     +    +  
Sbjct  673  ITEENSGALD-KVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQ  731

Query  863  LIAPYAPHIAEELWEKL-GNSESVTTAKYPEFEEKYLVESMKNYPVSFNGKMRFTMELSL  921
            LIAP+APH++EELW+ L +++ES++    P ++E  LVE+  +  V ++GK++  + ++ 
Sbjct  732  LIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAK  791

Query  922  DMSKEEIEKTVMADERTQKQLDGR  945
            D+S+EE++   +A+E+ Q ++ G+
Sbjct  792  DLSREELQEVALANEKVQAEIAGK  815


 Score =  181 bits (672),  Expect = 2e-46, Method: Compositional matrix adjust.
 Identities = 91/142 (65%), Positives = 118/142 (84%), Gaps = 0/142 (0%)

Query  3    YHFNKIEEKWQKYWADNQTFKASNDSEKPKYYVLDMFPYPSGAGLHVGHPLGYIASDIYA  62
            Y+   IE KWQ +WADN+TFK++ D+ KPK+Y LDMFPYPSGAGLHVGHP GY A+DI +
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RFKRHKGFNVLHPQGYDSFGLPAEQYAIQTGQHPAVTTENNIARYREQLDKIGFSFDWSR  122
            RFKR +G NVLHP G D+FGLPAEQYA++TG++PA  T +NIA ++ Q++ +GFS+DW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVRTSEPDYYKWTQWIFIQLFE  144
            EV T++P+YYKWTQWIF +L+E
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYE  145

1760) Weevi_1176 in NC_015144


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  455 bits (1714),  Expect = 7e-129, Method: Compositional matrix adjust.
 Identities = 306/722 (43%), Positives = 469/722 (65%), Gaps = 57/722 (7%)

Query  216  LTFLAEAEVNWCPDLGTVLANDEVI-NGLSERGGFPVIRKKMTQWMMRITAYADRLLTDL  274
            L++ AE  VNW  +LGT +AN+EV+ +G SERGG+PV+RK M QWM++ITAYA+RLL DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  275  DTIDWPEPIKEAQRNWIGKSKGASVLFSIEGNEEQIEVFTTRPDTIFGVSYVTLAPEHPL  334
            + +DWPE+IK+ QRNWIGKS GA+V F + + + ++ VFTTRPDT+FG +Y  LAPEH+L
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  335  VQKITTSDNRKKVEEYVEQTTKRSERERLSDVKHISGEFTGAYAIHPITQEKLPIWIGDY  394
            V+ ITTSD+   V +Y  Q++ +S+  R    K+ +G  TG+YAI+P+    +P+WI+DY
Sbjct  268  VDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAINPVNGKEMPVWIADY  327

Query  395  VLASYGTGAVMAVPAGDDRDYAFAKHFDLPIRPIFENHDLQEAAFTEKGNFKLINSDFLD  454
            VLASYGTGA+MAVPA D+RD  FAK+F+L I P++E  +++EAAFTE G    INSDFLD
Sbjct  328  VLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEAAFTEDGLH--INSDFLD  385

Query  455  GLDYPQAIEKIVHFLEDKNIGKGKTNFRLRDAVFSRQRYWGEPVP-AYFKDGVPYTIPTE  513
            GLD + AI K+V+ LE   +G+ +  +RLRD +FSRQRYWGEP+P     DG + ++P  
Sbjct  386  GLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPES  445

Query  514  ALPVILPEVDEYLPTKEGEPPLGRATKWAFDTLNKEVVENHLIDNKTIFPIELNTMPGWA  573
             LP++LP   +  P+  GE+PL+  T W       EV  ++ +  +     E NTMP WA
Sbjct  446  ELPLVLPVTKDIRPSGTGESPLANVTDWL------EVTREDGVKGRR----ETNTMPQWA  495

Query  574  GSSWYWMRYMDPDNENEFVSKDAVEYWQNVDLYIGGSEHATGHLLYSRFWQKFMFDKGWA  633
            GSSWY +RY+DP+N + +   + +  W  VD+Y+GG+EHA  HLLY+RFW+K ++D G  
Sbjct  496  GSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVV  555

Query  634  PTQEYAMKLINQGMILGVSAFVYRIQGSNTFVSYSLKDQYQVTPIHVDVSLLKDGTDELD  693
            PT+E   KL+NQGMILG S   YR ++  ++V+    ++ + + +HV+ +      +EL+
Sbjct  556  PTKEPFQKLFNQGMILGTS---YR-DSRGALVATDKVEKRDGSFFHVETG------EELE  605

Query  694  IEKFCTWREEYQDAEFILEEEKYITGREVEKMSKSKFNVLNPDIICEQYGADSLRLYEMF  753
                                      +   KMSKS  NV+NPD + EQYGAD+LR+YEMF
Sbjct  606  --------------------------QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMF  639

Query  754  LGPLEQSKPWNTQGISGVHSFLKKFWRLYHSGENDSFYVSEDEPTKEEYKILHQAIKKVD  813
            +GPL+ S +W+ +G+ G + FL +  RL  + E     ++E+++   + K+ ++++K V 
Sbjct  640  MGPLDASIAWSEEGLEGSRKFLDRVYRLITTKE-----ITEENSGALD-KVYNETVKAVT  693

Query  814  EDvnsfsfntsvstfMITVNELGKLKTNKRAILEPLAIILSPYAPHIAEELWHKLGYTS-  872
            E+V+   FNT+++ +M+ VN   K           +  +++P+APH++EELW+ L  ++ 
Sbjct  694  EQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGE  753

Query  873  SIAHADFPIFDEKWLIADSKEYPVSFNGKMKFLLELPLSLSKDEIQEIVMKDARTQKQLR  932
            SI+    P +DE  L+ +  E  V ++GK+K  L ++  LS++E+QE+ + + + Q ++ 
Sbjct  754  SISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIA  813

Query  933  DR  934
            ++
Sbjct  814  GK  815


 Score =  168 bits (623),  Expect = 1e-42, Method: Compositional matrix adjust.
 Identities = 84/153 (55%), Positives = 118/153 (78%), Gaps = 11/153 (7%)

Query  3    YNPSEIEPKWQQYWFDHKTFQAKNQSDKTKYYVLDMFPYPSGAGLHVGHPLGYIASDIYA  62
            Y+ + IEPKWQ +W D+ TF++  ++ K K+Y LDMFPYPSGAGLHVGHP GY A+DI +
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRLKGYNVLHPMGYDSFGLPAEQYAIQTGQHPAITTIVNIEGGVDKQGNTIPGYDKQL  122
            R+KR +G NVLHPMG D+FGLPAEQYA++TG++PA  T           ++ I+ + +Q+
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFT-----------AENIANFKRQI  112

Query  123  KRLGLGYDWDREIRTSNPNFYKWTQWIFNQLFD  155
            + LG++YDWDRE+ T++PN+YKWTQWIF +L++
Sbjct  113  NALGFSYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1761) leuS in NC_021985


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  454 bits (1710),  Expect = 1e-128, Method: Compositional matrix adjust.
 Identities = 359/739 (49%), Positives = 492/739 (67%), Gaps = 59/739 (7%)

Query  226  LAYASDAPVNWCPGLGTVLANEEVTADGRSERGNFPVFKAKLRQWNMRITAYAdrlledl  285
            LAY ++ PVNW   LGT +ANEEV +DG SERG +PV +  +RQW ++ITAYA+RLLEDL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  286  eeldWPEAIKLQQRNWIGRSEGARVDFPIDG--ENITVFTTRPDTLFGATYMVLAPEHPL  343
            EE+DWPE+IK  QRNWIG+S GA V F + +   ++TVFTTRPDTLFGATY VLAPEH+L
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  344  VEKFTPEAWPEGTHDVWTGGHATPSEavaayraqaaaKSDVERQAEAKDKTGVFIGAYAT  403
            V+ +T                +  +EAVA Y+ QA+ KSD+ R   AK+KTGV  G+YA 
Sbjct  268  VDAITT---------------SDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAI  312

Query  404  NPVNGERVPVFIADYVLMGYGTGAIMAVPAGDQRDFEFARAFELPIHCIVEPTDGRGTDT  463
            NPVNG  +PV IADYVL +YGTGAIMAVPA D+RD EFA+ F+L I  ++E  +      
Sbjct  313  NPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEE---  369

Query  464  ATWENAFASYDAKIINSSNDEVTLDGLGVAEAKARITEWMQSRGVGEGTVNFRLRDWLFS  523
                   A++    ++ ++D   LDGL+ A A A++ EW+++ GVG+  V +RLRDWLFS
Sbjct  370  -------AAFTEDGLHINSD--FLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  524  RQRYWGEPFPIVYDEDGIAHAlpesmlplelpeveDYSPRTFDPDDADTQPETPLSRNED  583
            RQRYWGEP+PI+  EDG + A+PES LPL LP   D  P            E+PL+   D
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTD  472

Query  584  WVNVTLDLGDGPRKYRRETNTMPNWAGSCWYEFRYLDPHNDQKLVDPEIERYWMGPREGL  643
            W++VT +  DG +  RRETNTMP+WAGS WY +RY+DPHN +KL D E+ + W+      
Sbjct  473  WLEVTRE--DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLP-----  524

Query  644  PHGGVDLYVGGAEHAVLHLLYARFWSKVLYDLGHVSSAEPFHKLFNQGMIQAYVYRDSRG  703
                VD+YVGGAEHAVLHLLYARFW KVLYDLG V++ EPF+KLFNQGMI +  YRDSRG
Sbjct  525  ----VDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRG  580

Query  704  IAVPAAEVEERDGDYYY--QGEKVSRLLGKMGKSLKNAVTPDEIAAEYGADTLRLYEMAM  761
              V++  VE RDG ++    GE + +  +KM+KSLKN V PD++  +YGADTLR+YEM M
Sbjct  581  ALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFM  640

Query  762  GPLDVSRPWDTRAVVGQFRLLQRLWRNVVDEDSGETTVTGAEPDEDTLRALHKAIDGVRQ  821
            GPLD S +W   ++ G  ++L+R+ R +   +  E    + +      +  + ++ +V +
Sbjct  641  GPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALD------KVYNETVKAVTE  694

Query  822  DLEGLRFNTAIAKVTELNNHLTKAGTAVPRQVAEPLVLMIAPLAPHIAEELWRRL-GHTE  880
            +++ ++FNTAIA++  + N   K +   + + A  +V +IAP+APH++EELW+ L +  E
Sbjct  695  QVDQMKFNTAIAQLMVFVNAANKEDKLFS-DYAKGFVQLIAPFAPHLGEELWQALTASGE  753

Query  881  SVVHQDFPVADPRYvvdetvtcvvqvKGKVKARLEVPPGISdeelekaaladekVVLALG  940
            S+     P  D   +V++ V  VVQ+KGKVKA+L V+ ++S EEL+  ALA+EKV   ++
Sbjct  754  SISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIA  813

Query  941  GAAVRKVIVRAPKLVNIVT  959
            G  + KVI  + KLVNIV 
Sbjct  814  GKDIIKVIAVPNKLVNIVI  832


 Score =  138 bits (507),  Expect = 2e-33, Method: Compositional matrix adjust.
 Identities = 77/150 (52%), Positives = 102/150 (68%), Gaps = 10/150 (6%)

Query  27   ADIEARWQDFWDADGTYAAPNPTGDLAGDPELVAKPKKFIMDMFPYPSGAGLHVGHPLGY  86
            + IE++WQ FW  + T+ +   +          +KPK + +DMFPYPSGAGLHVGHP GY
Sbjct  7    TAIEPKWQAFWADNHTFKTGTDA----------SKPKFYALDMFPYPSGAGLHVGHPEGY  56

Query  87   IATDVYARFQRMTGHNVLHTLGFDAFGLPAEQYAVQTGTHPRVSTEANIENMKAQLRRLG  146
             ATD+ +RF+R  GHNVLH +G DAFGLPAEQYA++TG +P   T  NI N K Q+  LG
Sbjct  57   TATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALG  116

Query  147  LGHDKRRSFATIDPDYYKWTQWIFLQIFNS  176
            ++ D  R   T DP+YYKWTQWIF ++++ 
Sbjct  117  FSYDWDREVNTTDPNYYKWTQWIFTKLYEK  146

1762) leuS in NC_017955


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  454 bits (1711),  Expect = 1e-128, Method: Compositional matrix adjust.
 Identities = 340/748 (46%), Positives = 491/748 (66%), Gaps = 77/748 (10%)

Query  231  LAYLNQAPVNWAPGLGTVLSNEEVTADGRSERGNFPVFRRPLTQWKMRITAYAERLLTDL  290
            LAY  + PVNW   LGT ++NEEV +DG SERG +PV R+P+ QW ++ITAYAERLL DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  291  DRLDWPDSLKQMQRNWIGRSTGARIRFGVGGEQVE--VFTTRPDTLFGATYLVLAPEHPL  348
            + +DWP+S+K+MQRNWIG+STGA + F V + + +  VFTTRPDTLFGATY VLAPEH+L
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  349  VETLTAAQWPADADPRWTagaatpaeavaaYQLQASRRSELERQTEGRDKTGVWLGVSAV  408
            V+++T+++                AEAVA Y+ QAS +S+L R   +++KTGVW G  A+
Sbjct  268  VDAITTSD---------------QAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAI  312

Query  409  NPLTGRDLPVFIADYVLTGYGTGAIMAVPGEDTRDWEFAQVFGLPVVRTVQPPADFDGGA  468
            NP+ G+++PV IADYVL++YGTGAIMAVP++D RDWEFA+ F L ++  ++  ++ + +A
Sbjct  313  NPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE-GGNVEEAA  371

Query  469  WTGGGPMINSSNEQLSLDGLDKAAAIATVTEWLVAHGHGEATTTYKLRDWLFSRQRYWGE  528
             T +G  INS      LDGLDKA+AIA + EWL A+G G+   TY+LRDWLFSRQRYWGE
Sbjct  372  FTEDGLHINSD----FLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGE  427

Query  529  PFPIVYAVDGPDADlpvavpesllpvllpdvddYSPKTFADDDADSKPEPPLSRATDWTT  588
            P+PI+   DG  + +P +    +LPV              D  + +  E+PL+  TDW  
Sbjct  428  PIPIIHWEDGTSTAVPESELPLVLPVT------------KDIRPSGTGESPLANVTDWLE  475

Query  589  VTLDLGDGPRTYRRETNTMPNWAGSCWYYLRYADPTNDQVLVDPELERYWLGPQEPgdvg  648
            VT +  DG +  RRETNTMP+WAGS WYYLRY DP N + L D EL + WL  +      
Sbjct  476  VTRE--DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVD------  526

Query  649  gvdlyvggvEHAVLHLLYARFWHKILFDLGHVSSEEPFRRLVNQGYISAFAYTDARGFYV  708
               +YVGG EHAVLHLLYARFWHK+L+DLG V++ EPF++L NQG I + +Y D+RG  V
Sbjct  527  ---IYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALV  583

Query  709  PAAEVVESDGQFLY--QGQPVDREYGKIGKSLKNVITPDEMVDAFGADTFRVYEMSTGPL  766
            ++  V   DG F+    G+ +++  +K++KSLKNV+ PD++V+ +GADT+RVYEM  GPL
Sbjct  584  ATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPL  643

Query  767  DQSRPWETKAVVGSQRLLQRIWRVVVDEETGAVRAGDVEPDADTSRALNRAVEAVRDGMT  826
            D S +W   ++ GS+++L+R+ R++   E     +G ++      +  N +V AV + + 
Sbjct  644  DASIAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALD------KVYNETVKAVTEQVD  697

Query  827  TLRFNIAIARITELTN------HLTSAYQPGAAVPRpvaetlvllvaplaphlaeelWAR  880
             ++FN AIA++  + N       L S Y  G             L+AP+APHL+EELW  
Sbjct  698  QMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFV----------QLIAPFAPHLGEELWQA  747

Query  881  LGHPDS----VAWASFPVADPQWLVDDTVEVAVQVNGKVRAQVKVPadadaavleaaara  936
            L  ++     V+W+S+  +    LV++ VE+ VQ++GKV+A++ V+ D     L+  A A
Sbjct  748  LTASGESISYVPWPSYDESK---LVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALA  804

Query  937  dERIAGHLDGATVRRVVAVPGRLVNFVL  964
            +E++ +++ G  + +V+AVP +LVN+V+
Sbjct  805  NEKVQAEIAGKDIIKVIAVPNKLVNIVI  832


 Score =  129 bits (473),  Expect = 8e-31, Method: Compositional matrix adjust.
 Identities = 79/148 (54%), Positives = 96/148 (65%), Gaps = 11/148 (7%)

Query  29   IELAWQDRWDAEGTFHTPNPVGPLSEGFDRVADRPKAFVMDMFPYPSGDGLHVGHPLGYL  88
            IE  WQ  W  + TF T              A +PK + +DMFPYPSG GLHVGHP GY 
Sbjct  9    IEPKWQAFWADNHTFKTGTD-----------ASKPKFYALDMFPYPSGAGLHVGHPEGYT  57

Query  89   GTDVTSRFLRMDGRNVLHPMGYDAFGLPAEQYAVQTGQHPRVTTEANIAAISRQLRRLGV  148
            +TD+ SRF R +G+NVLHPMG DAFGLPAEQYA++TG++P   T  NIA + RQ+  LG 
Sbjct  58   ATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGF  117

Query  149  DHDTRRTFATIDPGYYKWTQWIFRQVFE  176
              D  R   T DP YYKWTQWIF +++E
Sbjct  118  SYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1763) leuS in NC_013172


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  454 bits (1709),  Expect = 2e-128, Method: Compositional matrix adjust.
 Identities = 345/743 (47%), Positives = 488/743 (66%), Gaps = 60/743 (8%)

Query  245  LAYISETPVNWCPGLGTVLANEEVTTEGRSERGNFPVFTRRLRQWNMRITAYADRLLDDL  304
            LAY +E PVNW   LGT +ANEEV  +G SERG +PV  + +RQW ++ITAYA+RLL+DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  305  ERVDWPESIRTMQRNWIGRSHGAEITFPVRGLDGRAEAGFDVFTTRADTLFGATFCVLSP  364
            E VDWPESI+ MQRNWIG+S GA++TF V++    ++ +F VFTTR+DTLFGAT+ VL+P
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKD----TDKDFTVFTTRPDTLFGATYAVLAP  263

Query  365  EHELLTDPSALPAAWPEGTKDAWTGGAANPREAVTAYRDRAAALGDDERTADDRVKTGVF  424
            EH L+   +                 +++  EAV+ Y+ +A+  +D  RT   + KTGV 
Sbjct  264  EHALVDAIT-----------------TSDQAEAVADYKRQASLKSDLARTDLAKEKTGVW  306

Query  425  TGLTATNPMDGRELPVFTADYVLTGYGTGAIMAVPAEDERDHEFAERFELPVIRTVQPPE  484
            TG  A NP++G+E+PV  ADYVL++YGTGAIMAVPA+DERD EFA +F+L +I  ++   
Sbjct  307  TGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE-GG  365

Query  485  DFTGGAWTGDGITINSASAELDLNGLSQEEAKRRATEFVTHQGFGRARTTYRLRDWLFSR  544
            +   +A T DG+ INS      L+GL +  A  +  E +  +G G    TYRLRDWLFSR
Sbjct  366  NVEEAAFTEDGLHINSDF----LDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSR  421

Query  545  QRYWGEPFPIVYDPADPETPIALPESMLPVDLPDVTDFSPKTFDPMDADTEPQTPLSRAG  604
            QRYWGEP+PI+    +  T+ A+PES LP+ LP   D+ P            ++PL+   
Sbjct  422  QRYWGEPIPII--HWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVT  471

Query  605  DWVEVELDLGEGPKTYLRETNTMPQWAGSSWYHLRYIDPTEDDVLVRPENEAYWLGAREd  664
            DW+EV  + G   +   RETNTMPQWAGSSWY LRYIDP + + L   E    WL     
Sbjct  472  DWLEVTREDGVKGR---RETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPV---  525

Query  665  ggaggvdlyvggaEHAVLHLLYARFWHKVLFDRGDVSSQEPFQRLFNQGYIQAYAYTDSR  724
                  D+YVGGAEHAVLHLLYARFWHKVL+D G V+++EPFQ+LFNQG I + +Y DSR
Sbjct  526  ------DIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSR  579

Query  725  GVHvpaeevvaeaDGTYTYQ-GEPVTQEYGKMGKSLKNAVAPDDMYEEYGADTLRVYEMS  783
            G  V+++ V    ++ +  + GE + Q  +KM+KSLKN V PDD+ E+YGADTLRVYEM 
Sbjct  580  GALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMF  639

Query  784  MGPLDLSRPWETRAVVGSQRFLQRLWRLVVDEETGVLTVSDEPADLATKQAAHRTIDGVA  843
            MGPLD S +W   ++ GS++FL+R+ RL+   E     +++E ++ A  +  + T+ +V+
Sbjct  640  MGPLDASIAWSEEGLEGSRKFLDRVYRLITTKE-----ITEENSG-ALDKVYNETVKAVT  693

Query  844  RDMDRMHFNTAIAKLIELVNHLTKQLTSTGSTPReaveplvllvaplaphlaeelWARLG  903
             ++D+M FNTAIA+L+ +VN   K+    +  ++     +V L+AP+APHL+EELW  L 
Sbjct  694  EQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAK----GFVQLIAPFAPHLGEELWQALT  749

Query  904  HTG-SISRVPYPAADPELLKDEQVTCVIQVKGKVRHRIEVDPEISEEDLEAAVMAEPRVQ  962
             +G SIS VP P+ D   L +++V  V+Q+KGKV+ ++ V  ++S E+L+   +A+ +VQ
Sbjct  750  ASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQ  809

Query  963  ELLEGQTLRKLIIRAPKIVNIVI  985
              + G+ + K+I  + K+VNIVI
Sbjct  810  AEIAGKDIIKVIAVPNKLVNIVI  832


 Score =  122 bits (446),  Expect = 1e-28, Method: Compositional matrix adjust.
 Identities = 67/114 (59%), Positives = 86/114 (76%), Gaps = 0/114 (0%)

Query  59   KMYIMDMFPYPSGAGLHVGHPLGYIATDVVARHQRMLGKNVLYTMGYDAFGLPAEQYAVQ  118
            K Y +DMFPYPSGAGLHVGHP GY ATD+++R +R  G NVL  MG DAFGLPAEQYA++
Sbjct  33   KFYALDMFPYPSGAGLHVGHPEGYTATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMD  92

Query  119  TGTHPRTTTEANVANMRRQLHRLGLSHDPRRSLATTDPAFVKWTQWIFLRIFDS  172
            TG +P   T  N+AN +RQ++ LG+S D  R + TTDP + KWTQWIF ++++ 
Sbjct  93   TGNDPAEFTAENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEK  146

1764) Emtol_4026 in NC_018748


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  453 bits (1707),  Expect = 2e-128, Method: Compositional matrix adjust.
 Identities = 306/740 (42%), Positives = 474/740 (65%), Gaps = 64/740 (8%)

Query  206  LTYLSEAVVNFCPALGMVLSNDEV-KDGVSERGGYPVIQKKMQQWMMRITAYADRLITGL  264
            L+Y +E  VN    LG  ++N+EV  DG SERGGYPV++K M+QWM++ITAYA+RL+ +L
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  265  DLVDWSDSLKEQQRNWIGRSVGAMVKFGVENKPETQIEVFTTRVDTIYGVSFLVLAPEHE  324
            + VDW++S+K+ QRNWIG+S GA V F V +  + ++ VFTTR DT++G ++ VLAPEH 
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKD-TDKDFTVFTTRPDTLFGATYAVLAPEHA  266

Query  325  LVASLTTPQQKESIDNYIAETQKRSELDRMSDVRTVSGAFTGSYCINPFNGEKVPIWIAD  384
            LV ++TT++Q E++ +Y  ++  +S+L R    +  +G  TGSY INP NG  +P+WIAD
Sbjct  267  LVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAINPVNGKEMPVWIAD  326

Query  385  YVLAGYGTGAVMGVPSGDQRDWNFATHFNLPIIQILDSQADIENQADATKEGKYINSGMI  444
            YVLA+YGTGA+M+VP+ D+RDW+FA +FNL II +L++ +++E +A  T +G  INS+ +
Sbjct  327  YVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEG-GNVE-EAAFTEDGLHINSDFL  384

Query  445  NGLEYKEATSKLITWLEEKGMGKGKVNYRLRDAVFARQRYWGEPVPVFFKNDENGNPLPY  504
            +GL+   A +K++ WLE  G+G+ +V YRLRD +F+RQRYWGEP+P++  +D  + ++P 
Sbjct  385  DGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVP-  443

Query  505  LIDKNDLPLVLPEIDKYLPTEDGEPPLGRAEGW-------NYNGNPYELSTMPGWAGSSW  557
                ++LPLVLP      P+  GE+PL+   +W         +G   E +TMP WAGSSW
Sbjct  444  ---ESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVKGRR-ETNTMPQWAGSSW  499

Query  558  YWFRYMDANNDQEFASKEAIDYWQNVDLYLGGTEHATGHLLYSRFWNKFLKDRGYVPQEE  617
            Y +RY+D++N + +A  E +  W  VD+Y+GG+EHA  HLLY+RFW+K L D G VP  E
Sbjct  500  YYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKE  559

Query  618  YAMKLINQGMIMGRSSFVYRVKDSEKVTFVSYGLKDKYDTTKLHVDVNIVENDVLDIDKF  677
               KL+NQGMI+G S   YR     + ++V+ +  +K D + +HV+              
Sbjct  560  PFQKLFNQGMILGTS---YR---DSRGALVATDKVEKRDGSFFHVETG------------  601

Query  678  KATRNDIGDNPQFIFEDDGPSKGKYVCGSEVEKMSKSKFNVVNPDTIVERYGADTFRLYE  737
                +++ + P                     KMSKS  NVVNPD +VE+YGADT+R+YE
Sbjct  602  ----EELEQAP--------------------AKMSKSLKNVVNPDDVVEQYGADTLRVYE  637

Query  738  MFLGPLTESKPWDTRGIEGTYRFVRKLWRLFFDQNGKYLVVDAEPTKDELKSLHKTIKKV  797
            MF+GPL  S +W   G+EG+ +F+ ++ RL+  ++     +  E +    K  + T+K V
Sbjct  638  MFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKE-----ITEENSGALDKVYNETVKAV  692

Query  798  NEDIEAFSFNTSVSSFMICVNELSDLKCHKKAILEQLLIILSPYAPHVTEELWNVL-GNT  856
             E+++   FNT+++ +M+ VN  +            ++ +++P+APH+ EELW+ L ++ 
Sbjct  693  TEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASG  752

Query  857  DSITAQSFPSHEEKYLVEDSFEYPIQINGKVRATLNFPADMSKEEIEKQVLANELVIKWL  916
            +SI+  + PS +E  LVE+  E  +QI+GKV+A L  + D+S+EE++   LANE V   +
Sbjct  753  ESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEI  812

Query  917  DGASPKKIIVVPKRIVNVVI  936
             G    K+I VP+++VN+VI
Sbjct  813  AGKDIIKVIAVPNKLVNIVI  832


 Score =  177 bits (657),  Expect = 2e-45, Method: Compositional matrix adjust.
 Identities = 89/145 (62%), Positives = 115/145 (80%), Gaps = 0/145 (0%)

Query  1    MSEFNHREIEKKWQQVWEENQTYKVEIDHTKPKYYVLDMFPYPSGAGLHVGHPLGYIATD  60
            M+ ++H  IE KWQ  W +N+T+K   D +KPK+Y LDMFPYPSGAGLHVGHP GY ATD
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   IYSRYKRLKGFNVLHPMGFDSFGLPAEQYAIQTGQHPAITTENNITTYISQLKKIGFCYD  120
            I SR+KR +G NVLHPMG D+FGLPAEQYA++TG++PA  T +NI+ +  Q++ +GF YD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WSREVRTSDAKYYKWTQWIFMELFN  145
            W REV T+D++YYKWTQWIF  L++
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYE  145

1765) leuS in NC_016620


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  453 bits (1707),  Expect = 3e-128, Method: Compositional matrix adjust.
 Identities = 297/680 (44%), Positives = 446/680 (66%), Gaps = 51/680 (7%)

Query  204  LAFLAETAVNWCPGLGTVLANDEV-KDGLSVRGSHPVEQKKMQQWCLRVSAYAPRLLDGL  262
            LA+ AE +VNW   LGT +AN+EV  DG S RG+ PV +K M+QW L+++AYA RLL++L
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  263  DELNWSDSLKEMQKNWIGKSTGAEVKFDIKDREEKIEVFTTRADTIFGVSFMVLAPESDY  322
            +E++W++S+K+MQ+NWIGKSTGA+V F +KD +  + VFTTR+DT+FG ++ VLAPE   
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  323  VSLVTTDEQRAAVEQYLEDTKKRSERDRLADVKRVTGVFTGAYCIHPFTGKDIPIWIGDY  382
            V  +TT +Q  AV +Y  ++  +S+  R    K  TGV TG+Y I+P  GK++P+WI+DY
Sbjct  268  VDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAINPVNGKEMPVWIADY  327

Query  383  VLGGYGTGAVMAVPAHDSRDYAFAKHFGIEITQVVSGGDISEESYDAKEGTLMNSDFLNG  442
            VL++YGTGA+MAVPAHD RD  FAK+F ++I  V+ GG++ E ++ + +G  +NSDFL+G
Sbjct  328  VLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEAAF-TEDGLHINSDFLDG  386

Query  443  LSVQDAIAKMITEVESRGLGQKQTNYRLRDAIFSRQRYWGEPFP-IYFKDGVPTPLSMDD  501
            L    AIAKM+  +E+ G+G+ +  YRLRD +FSRQRYWGEP+P I   DG +T+++  +
Sbjct  387  LDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESE  446

Query  502  LPLQLPEVDKFLPTEDGQPPLGRAENW---TTKDG--HPLEMSTMPGFAGSSAYYLRYMD  556
            LPL LP    + P+  G++PL+   +W   T  DG     E +TMP  AGSS YYLRY+D
Sbjct  447  LPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYID  506

Query  557  PHNEEGLVSKDANNYWQDVDLYIGGAEHATGHLIYSRYWNKFLFDIGYVCKEEPFKRLVN  616
            PHN E L   +  + W  VD+Y+GGAEHA  HL+Y+R+W+K L+D+G V   EPF++L N
Sbjct  507  PHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFN  566

Query  617  QGMIQGRSNFVYRLKGKNEFVSLGLKDQYDTQEIHVDVNIVHNDQLDMDAFKAWRPEFKD  676
            QGMI G S   YR  ++  +V+ +  ++ D   +HV+      ++L+  +          
Sbjct  567  QGMILGTS---YR-DSRGALVATDKVEKRDGSFFHVET----GEELEQAP----------  608

Query  677  ATFITESVDGKDVYNCGYAVEKMSKSMFNVVNPDTIVENYGADTLRLYEMFLGPLEQSKP  736
                                 KMSKS+ NVVNPD +VE+YGADTLR+YEMF+GPL+ S +
Sbjct  609  --------------------AKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIA  648

Query  737  WNTNGIEGVHRFLKKLWNLFYKDEKLCVVSDAPSADELKVLHTCIKKVNEDIDTFSFNTS  796
            W+ +G+EG ++FL ++  L+   E    +++  S+   KV +  +K V E++D   FNT+
Sbjct  649  WSEEGLEGSRKFLDRVYRLITTKE----ITEENSGALDKVYNETVKAVTEQVDQMKFNTA  704

Query  797  ISAFMICVNDLSKLKCHKKdilndliillSPFAPHFCEELWQEL-GHSESITFASMPELN  855
            I+ +M+ VN  +K      D  ++++ L++PFAPH+ EELWQ L + +ESI++ + P  +
Sbjct  705  IAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYD  764

Query  856  ESYLVESTHKYPISVNGKMR  875
            ES LVE+     + ++GK++
Sbjct  765  ESKLVENDVEIVVQIKGKVK  784


 Score =  185 bits (687),  Expect = 1e-47, Method: Compositional matrix adjust.
 Identities = 93/142 (66%), Positives = 117/142 (83%), Gaps = 0/142 (0%)

Query  3    YNFQEIETKWQKYWNDNQTFKAHESSSKPKYYILDMFPYPSGAGLHVGHPLGYIASDIYT  62
            Y+   IE KWQ +W DN+TFK+   +SKPK+Y LDMFPYPSGAGLHVGHP GY A+DI +
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RFKRLEGYNVLHPMGYDAFGLPAEQYAIQTGRHPADTTRENIARYREQLDKIGFSYDWNR  122
            RFKR +G NVLHPMG DAFGLPAEQYA++TG +PA+ T ENIA ++ Q++ +GFSYDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVQTCDPKYYKWTQWAFIQMFE  144
            EV+T DP+YYKWTQW F +++E
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYE  145

1766) leuS in NC_009614


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  453 bits (1707),  Expect = 3e-128, Method: Compositional matrix adjust.
 Identities = 310/728 (43%), Positives = 451/728 (62%), Gaps = 64/728 (8%)

Query  204  IAYLGETMVNWCPQLGTVLANDEVV-DGVSERGGFPVVQKKMRQWCLRVSAYAQRLLDGL  262
            +AY +E  VNW  +LGT +AN+EV+ DG SERGG+PVV+K MRQW L+++AYA+RLL++L
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  263  DTVDWTDSLKETQRNWIGRSEGTEVQFKVKDSDIEFTIFTTRADTMFGVTFMVLAPESEL  322
            + VDW +S+K+ QRNWIG+S G++V FKVKD+D +FT+FTTR+DT+FG T+ VLAPE  L
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  323  VPQLTTEAQKAEVEAYLDRTKKRTERERIA-DRRVTGVFSGSYAINPFTGEAVPVWISDY  381
            V  +TT  Q   V  Y  ++  +++  R    +  TGV +GSYAINP  G  +PVWI+DY
Sbjct  268  VDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAINPVNGKEMPVWIADY  327

Query  382  VLAGYGTGAIMAVPAHDSRDYAFAKHFNLPIVPLVEGCDVSEESFDAKEGIVCNSPRKDV  441
            VLA+YGTGAIMAVPAHD RD  FAK+FNL I+P++EG +V E +F + +G+  N      
Sbjct  328  VLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEAAF-TEDGLHIN------  380

Query  442  TPYCDLSLNGLTIKEAIAATKEYVKAHNLGRVKVNYRLRDAIFSRQRYWGEPFPVYY-KN  500
                D+ L+GL    AIA   E + A+ +G  +V YRLRD +FSRQRYWGEP+P+    +
Sbjct  381  ---SDF-LDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWED  436

Query  501  GMPYMIDSSKLPLELPEVAKFLPTETGEPPLGHATKWAWDVEKGEVVENNLIDNVTIFPL  560
            G +  +  S LPL LP    + P+ TGE+PL++ T W  +V + + V             
Sbjct  437  GTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWL-EVTREDGVKGR---------R  486

Query  561  ELNTMPGFAGSSAYYLRYMDPHNAQALVSEKADHYWQNVDLYVGGTEHATGHLIYSRFWN  620
            E NTMP  AGSS YYLRY+DPHN++ L  E     W  VD+YVGG+EHA  HL+Y+RFW+
Sbjct  487  ETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWH  546

Query  621  KFLHDLGVSIKEEPFQKLVNQGMIQGRSNFVYRIKDTNTFVSLNLKDQYETTPLHVDVNI  680
            K L DLGV    EPFQKL NQGMI G S   YR     ++V+ +  ++ + + +HV+   
Sbjct  547  KVLYDLGVVPTKEPFQKLFNQGMILGTS---YR-DSRGALVATDKVEKRDGSFFHVE---  599

Query  681  VSNDILDVEAFKAWRPEYNDAEFILEDGKYICGWAVEKMSKSMYNVVNPDMIVEKYGADT  740
             + + L+  +                           KMSKS+ NVVNPD +VE+YGADT
Sbjct  600  -TGEELEQAP--------------------------AKMSKSLKNVVNPDDVVEQYGADT  632

Query  741  LRMYEMFLGPVEQSKPWDTNGIDGVHRFLKKLWNLFYSRTDEFLPVEGEPTKEELKAIHK  800
            LR+YEMF+GP++ S +W  +G++G ++FL ++  L+ ++      +  E +    K  + 
Sbjct  633  LRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKE-----ITEENSGALDKVYNE  687

Query  801  LIKKVTGDIETFSYNTSISAFMICVNELTSLKCRNKEVLSNLIILLAPFAPHYAEELWEA  860
             +K VT +++   +NT+I+ +M+ VN          +    ++ L+APFAPH +EELW+A
Sbjct  688  TVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  861  LGNTT-SVCDAQWPAFNEDYLKEDTVKYTISFNGKARFTMDFAADADNNTIQTTVMADEQ  919
            L  +  S+    WP+++E  L E+ V   + ++GK +  +  A D   + +Q   +A+E+
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807

Query  920  AQKWIEGK  927
             Q  I GK
Sbjct  808  VQAEIAGK  815


 Score =  169 bits (624),  Expect = 1e-42, Method: Compositional matrix adjust.
 Identities = 84/142 (60%), Positives = 111/142 (79%), Gaps = 0/142 (0%)

Query  3    YNFREIEKKWQQRWAENHTYQVTEDESKKKFYVLNMFPYPSGAGLHVGHPLGYIASDIYA  62
            Y+   IE KWQ  WA+NHT++   D SK KFY L+MFPYPSGAGLHVGHP GY A+DI +
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRLQGFNVLNPMGYDAYGLPAEQYAIQTGQHPAITTVNNINRYREQLDKIGFSFDWNR  122
            R+KR QG NVL+PMG DA+GLPAEQYA++TG++PA  T +NI  ++ Q++ +GFS+DW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVRTCEPGYYHWTQWAFQQMFN  144
            EV T +P YY WTQW F ++++
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYE  145

1767) CA2559_04530 in NC_014230


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  453 bits (1706),  Expect = 3e-128, Method: Compositional matrix adjust.
 Identities = 295/726 (41%), Positives = 454/726 (63%), Gaps = 62/726 (8%)

Query  206  LTYLAESEVNWCPELGTVLANDEIV-NGVSERGGFPVVRKKMTQWSMRISAYAERLLQDL  264
            L+Y AE  VNW  ELGT +AN+E++ +G SERGG+PVVRK M QW ++I+AYAERLL+DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  265  NDIDWPEPLKESQRNWIGKSIGAHVDFKVKGHNEKIGVFTTRPDTIFGVTFMTLAPEHEL  324
            +++DWPE++K+ QRNWIGKS GA+V FKVK+ +  + VFTTRPDT+FG T+  LAPEH L
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  325  VAKLTTPKQKDAVEAYIEKTAKRSERERMADVKTISGVFTGAYAEHPFTKEPVAIWIGDY  384
            V  +TT+ Q +AV  Y  +++ +S+  R    K  +GV TG+YA +P     +++WI+DY
Sbjct  268  VDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAINPVNGKEMPVWIADY  327

Query  385  VLAGYGTGAVMAVPCGDQRDYDFANHFAGQEGMTPIVNIFKDVDVSEEAFADKEKTIITN  444
            VLA+YGTGA+MAVP  D+RD +FA++F  +     I+ ++ + +V E AF+  E  +  N
Sbjct  328  VLASYGTGAIMAVPAHDERDWEFAKQFNLD-----IIPVLEGGNVEEAAFT--EDGLHIN  380

Query  445  SNFLNDLPYKKAMKLAIYKLEEQGSGQGQTNYRLRDAVFSRQRYWGEPFPVYY-KNGIPQ  503
            S+FL++L    A+   +  LE +G G+ +  YRLRD +FSRQRYWGEP+P+    +G + 
Sbjct  381  SDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTST  440

Query  504  MIEEKHLPITLPEVEKYLPTEEGEPPLGRADVWAWNTENAQVVSNDLVNSDTVFPLELNT  563
             + E +LP+ LP      P+  GE+PL+    W       +V  +D V++      E NT
Sbjct  441  AVPESELPLVLPVTKDIRPSGTGESPLANVTDW------LEVTREDGVKGRR----ETNT  490

Query  564  MPGWAGSSWYFFRYMEKAMRNETFASKDAMNYWQEVDLYIGGSEHATGHLLYARFWTKFL  623
            MP WAGSSWY++RY++ +   E +A  + ++ W  VD+Y+GG+EHA  HLLYARFW K L
Sbjct  491  MPQWAGSSWYYLRYID-PHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWHKVL  549

Query  624  YDIKAVPVKEFAKKLINQGMILGTSAFVYRKEETNVFISKNLIGDENVQPIHADVSMVNA  683
            YD+  VP KE  +KL+NQGMILGTS   YR           L++ ++V+  ++    V++
Sbjct  550  YDLGVVPTKEPFQKLFNQGMILGTS---YRDSRG------ALVATDKVEKRDGSFFHVET  600

Query  684  SSELDLEAFKAWRPEFKDAEFILEDNKYIVGHEVEKMSKSKYNVVNPDDICAQYGADTLR  743
            + EL+                          +   KMSKS  NVVNPDD+  QYGADTLR
Sbjct  601  GEELE--------------------------QAPAKMSKSLKNVVNPDDVVEQYGADTLR  634

Query  744  LYEMFLGPLEQAKPWNTAGITGVHSFLKKLWKLYHNGENFEVTDAEPNKESL-KTLHKTI  802
            +YEMF+GPL+ + +W+  G+ G + FL ++ +L    E      +E N  +L K  + T+
Sbjct  635  VYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEI-----TEENSGALDKVYNETV  689

Query  803  KKVEEDIENFSFNTSVSTFMIAVNELSSQKCNSRAILEPLAVLISPYAPHIAEELWEKL-  861
            K V E++++  FNT+++ +M+ VN  + +          +  LI+P+APH++EELW+ L 
Sbjct  690  KAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALT  749

Query  862  GHSTSIATAEFPKFEEKHLVESSKAYPISFNGKMRFTMELPLDLSKDDIEKAVMAHEKTA  921
            + + SI+    P ++E  LVE+     + ++GK++  + ++ DLS+++++   +A+EK  
Sbjct  750  ASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQ  809

Query  922  GYLDGR  927
            + + G+
Sbjct  810  AEIAGK  815


 Score =  176 bits (651),  Expect = 8e-45, Method: Compositional matrix adjust.
 Identities = 85/145 (59%), Positives = 115/145 (80%), Gaps = 0/145 (0%)

Query  1    MSNYHFNEIEKKWQQYWSKNGTFHASNTSEKPKYYVLDMFPYPSGAGLHVGHPLGYIASD  60
            M+ Y+   IE KWQ +W+ N TF ++  + KPK+Y LDMFPYPSGAGLHVGHP GY A+D
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   IYARYKRHKGFNVLHPQGYDSFGLPAEQYAIQTGQHPRITTEENIKTYRRQLDQIGFSFD  120
            I +R+KR +G NVLHP G D+FGLPAEQYA++TG++P   T ENI  ++RQ++ +GFS+D
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WSRELRTSEPEFYKWTQWIFTELFN  145
            W RE+ T++P++YKWTQWIFT L++
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYE  145

1768) leuS in NC_008255


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  452 bits (1702),  Expect = 6e-128, Method: Compositional matrix adjust.
 Identities = 308/709 (44%), Positives = 458/709 (65%), Gaps = 63/709 (8%)

Query  206  LTYLSETMVNWCPGLGTVLANEEV-KDGLSERGGFPVERKKMKQWSMRITAYADRLLKGL  264
            L+Y +E  VNW   LGT +ANEEV  DG SERGG+PV RK M+QW ++ITAYA+RLL +L
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  265  DTIDWPEAMKEMQRYWIGKSLGAMLTFKVVDKDMELTVFTTRIDTTFGVTYVSIAPEHEW  324
            + +DWPE++K+MQR WIGKS GA +TFKV D D ++TVFTTR DT FG TY  +APEH  
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  325  IGALTSPEQKAAVEEYVTKAKNRSERDRMSDVKTVSGCFTGSYVTNPFNNEKIPVWIADY  384
            ++A+T+++Q  AV +Y  +A  +S+  R    K  +G  TGSY  NP N   +PVWIADY
Sbjct  268  VDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAINPVNGKEMPVWIADY  327

Query  385  VLAGYGTGVVMAVPSSDERDYKFASFYKLPIISVQEGAHTDITKEDFDPKAGTMINSGFL  444
            VLA+YGTG +MAVP+ DERD  FA  ++L II+V EG++ +     F    G  INS+FL
Sbjct  328  VLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVE--EAAF-TEDGLHINSDFL  384

Query  445  NGLTVKQAIPEAIKFIEEKKIGFAKINFKMRDSIFGRQRYWGEPIPVSY-KNDIPYVLNE  503
            +GL    AI+  +  +E   +G  ++ +++RD +F+RQRYWGEPIP+    ++ +  + E
Sbjct  385  DGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPE  444

Query  504  SELPLALPAIDEYKPTETGEPPLA---------RNKAFADKGYELSTMPGWAGSSWYFMR  554
            SELPL LP   + +P+ TGE+PLA         R+ +  ++  E +TMP WAGSSWY++R
Sbjct  445  SELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVKGRR-ETNTMPQWAGSSWYYLR  503

Query  555  YMDPQNKTAVAAADKINYWGQVDLYMGGAEHATGHLLYSRFWNKFLFDMGITPNDEPFAK  614
            Y+DP+N   +A  + ++ W  VD+Y+GGAEHA  HLLY+RFW+K L+D+G+ P  EPF K
Sbjct  504  YIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQK  563

Query  615  LINQGMIQGVSKFAYRINGTNKFVSAGLKKEYDTTPIHVDVSIVHNDVLDTEAFKKWRPD  674
            L+NQGMI G S   YR ++   +V+++     D + +HV+ +    + L+  +       
Sbjct  564  LFNQGMILGTS---YR-DSRGALVATDKVEKRDGSFFHVETG----EELEQAP-------  608

Query  675  FASAEFILENNTYVCGSEVEKMSKSKFNVVNPDDIVNKYGADTLRMYEMFLGPLEQSKPW  734
                                KMSKS  NVVNPDD+V++YGADTLR+YEMF+GPL+ S +W
Sbjct  609  -------------------AKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAW  649

Query  735  NTNGIEGVYKFLNRFWRLFHDTAGNFAVSDAQPTAEELKVLHKTLKRVEEDIERFSFNTP  794
            + +G+EG  KFL+R  RL+        +++ ++ A + KV + T+K V E++++  FNT+
Sbjct  650  SEEGLEGSRKFLDRVYRLITTK----EITEENSGALD-KVYNETVKAVTEQVDQMKFNTA  704

Query  795  VSTFMICVNELGSLKCNK--RTILEPLTIALSPLAPHIAEELWSLLGHTTSVSTATYPAW  852
            ++ +M+ VN  ++ K +K        +   ++P+APH++EELW  L  T+S  + +Y +W
Sbjct  705  IAQLMVFVN--AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQAL--TASGESISYVPW  760

Query  853  ---DEKFLVESNHEYPISINGKMRAKLNLPVDMPAAEVEQQVLANEVVQ  898
               DE  LVE++ E  + I+GK++AKL ++ D++  E+++  LANE VQ
Sbjct  761  PSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQ  809


 Score =  174 bits (645),  Expect = 2e-44, Method: Compositional matrix adjust.
 Identities = 86/142 (61%), Positives = 116/142 (82%), Gaps = 0/142 (0%)

Query  4    YHFGEVENKWQSKWNAEKTFKALENSSKPKYFVLDMFPYPSGSGLHVGHPLGYIASDIMA  63
            Y+   +E KWQ+ W  + TFK+  ++SKPK++ LDMFPYPSG+GLHVGHP GY A+DI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYKRIKGYNVLHPMGFDSFGLPAEQYAVQTGQHPAITTEQNIARYIEQLNKIGFSFDWDR  123
            R+KR +G NVLHPMG D+FGLPAEQYA++TG++PA  T +NIA +  Q+N +GFS+DWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EIRTSDPAYYKWTQWIFIQLFN  145
            E+ T+DP YYKWTQWIF +L++
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYE  145

1769) leuS in NC_006347


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  452 bits (1702),  Expect = 7e-128, Method: Compositional matrix adjust.
 Identities = 304/724 (42%), Positives = 462/724 (64%), Gaps = 73/724 (10%)

Query  204  IAYLGNTMVNWCPALGTVLANDEVV-DGVSERGGYPVIQKVMRQWCLRVSAYAQRLLDGL  262
            +AY ++  VNW   LGT +AN+EV+ DG SERGGYPV++K MRQW L+++AYA+RLL++L
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  263  ETVEWTDSLKETQRNWIGRSEGAEMNFKVKDSDIEFTIFTTRADTVFGVTFMVLAPESEL  322
            E V+W +S+K+ QRNWIG+S GA++ FKVKD+D +FT+FTTR+DT+FG T+ VLAPE  L
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  323  VAKLTTPEQKAEVDAYLDRTKKRTERERIA-DRSVSGVFSGSYAINPLTNEPIPVWISDY  381
            V  +TT++Q   V  Y  ++  +++  R    +  +GV +GSYAINP+    +PVWI+DY
Sbjct  268  VDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAINPVNGKEMPVWIADY  327

Query  382  VLAGYGTGAIMAVPAHDSRDYAFAKHFNLEIRPLIEGCDVSEESFDAKEGIMMNSPRPGA  441
            VLA+YGTGAIMAVPAHD RD  FAK+FNL+I P++EG +V E +F + +G+ +NS     
Sbjct  328  VLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEAAF-TEDGLHINSD----  382

Query  442  PEGGLVLNGLTVKEAIAKTKEYIKATGLGRVKVNFRLRDAIFSRQRYWGEPFPVYY-KDG  500
                  L+GL    AIAK  E + A G+G  +V +RLRD +FSRQRYWGEP+P+    DG
Sbjct  383  -----FLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDG  437

Query  501  MPYMIDESCLPLELPEVAKFLPTETGEPPLGHATKWAWDTVNKCVTDNENIDNRTIFPLE  560
             +  + ES LPL LP    + P+ TGE+PL++ T W        VT ++ +  R     E
Sbjct  438  TSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWL------EVTREDGVKGRR----E  487

Query  561  LNTMPGFAGSSAYYLRYMDPRNHEALVSPAVDQYWKNVDLYVGGTEHATGHLIYSRFWNK  620
             NTMP  AGSS YYLRY+DP+N E L    + + W  VD+YVGG+EHA  HL+Y+RFW+K
Sbjct  488  TNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWHK  547

Query  621  FLHDWGISVAEEPFQKLVNQGMIQGRSNFVYRIKDTNTFVSLNLKDQYEVTPIHVDVNIV  680
             L D G+  + EPFQKL NQGMI G S   YR     ++V+ +  ++ + + +HV+    
Sbjct  548  VLYDLGVVPTKEPFQKLFNQGMILGTS---YR-DSRGALVATDKVEKRDGSFFHVE----  599

Query  681  SNDILDLEAFKAWRPEYETAEFILEDGKYICGWAVEKMSKSMFNVVNPDMIVEKYGADTL  740
            + + L+  +                           KMSKS+ NVVNPD +VE+YGADTL
Sbjct  600  TGEELEQAP--------------------------AKMSKSLKNVVNPDDVVEQYGADTL  633

Query  741  RMYEMFLGPVEQSKPWDTNGIDGVHRFIKKFWSLFYDRNGEYLVKDEPATKEELKALHKL  800
            R+YEMF+GP++ S +W  +G++G ++F+ +   L+  ++   +  +++++ +  K  +  
Sbjct  634  RVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKE---ITEENSGALD--KVYNET  688

Query  801  IKKVTGDIEQFSYNTSVSAFMICVNELSSLKCNKKEVL-----EQLIVVLAPFAPHVCEE  855
            +K VT +++Q  +NT+++ +M+ VN       NK + L       ++ ++APFAPH+ EE
Sbjct  689  VKAVTEQVDQMKFNTAIAQLMVFVNA-----ANKEDKLFSDYAKGFVQLIAPFAPHLGEE  743

Query  856  LWDTLGNTT-SVCDAQWPTFNEQYLVEDTVNYTISFNGKARFNMEFPADAASDAIQATVL  914
            LW++L  +  S+    WP+++E  LVE+ V+  + ++GK + ++  + D + + +Q   L
Sbjct  744  LWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVAL  803

Query  915  ADER  918
            A+E+
Sbjct  804  ANEK  807


 Score =  173 bits (640),  Expect = 5e-44, Method: Compositional matrix adjust.
 Identities = 86/142 (61%), Positives = 113/142 (80%), Gaps = 0/142 (0%)

Query  3    YNFREIEKKWQKIWVDNHTYQVNEDASKQKFYVLNMFPYPSGAGLHVGHPLGYIASDIYA  62
            Y+   IE KWQ +W DNHT++   DASK KFY L+MFPYPSGAGLHVGHP GY A+DI +
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRLQGFNVLNPMGYDAYGLPAEQYAIQTGQHPAITTVNNINRYREQLDKIGFSFDWNR  122
            R+KR QG NVL+PMG DA+GLPAEQYA++TG++PA  T +NI  ++ Q++ +GFS+DW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EIRTCDPEYYHWTQWAFIKMFN  144
            E+ T DP+YY WTQW F K+++
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYE  145

1770) leuS in NC_013222


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  451 bits (1698),  Expect = 1e-127, Method: Compositional matrix adjust.
 Identities = 321/726 (45%), Positives = 467/726 (65%), Gaps = 60/726 (8%)

Query  205  LTYLAEAEVNWCPELGTVLANDEVV-NGVSERGGFPVVRKKMTQWMMRITAYAQRLLDGL  263
            L+Y AE  VNW  ELGT +AN+EV+ +G SERGG+PVVRK M QWM++ITAYA+RLL++L
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  264  DEIDWPQPLKDAQTNWIGRSVGASVIFKTVPNAHQAESFDIEVFTTRPDTIFGVSFMTLA  323
            +E+DWP+++KD Q NWIG+S GA+V FK V ++++    D+ VFTTRPDT+FG ++  LA
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFK-VKDTDK----DFTVFTTRPDTLFGATYAVLA  262

Query  324  PEHELVGRITTPEQQEEVQAYIEATSRRSERDRMADVKTVSGAFTGAYAAHPLTGEPVPV  383
            PEH LV+ ITT++Q E V  Y   +S +S+  R    K  +G  TG+YA +P+ G  +PV
Sbjct  263  PEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAINPVNGKEMPV  322

Query  384  WIGDYVLAGYGTGAVMSVPCGDQRDYDFAKHFELPIPNIFEGVSLEEGAYEEKDGVVIAQ  443
            WI+DYVLA+YGTGA+M+VP  D+RD +FAK+F+L I  ++EG ++EE+A+ E DG+ I +
Sbjct  323  WIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEAAFTE-DGLHI-N  380

Query  444  SGFISGLGREAATRKVVDALEEKGLGRGTINYRLRDAVFSRQRYWGEPFPVYYDADGlpr  503
            S+F+ GL++ +A  K+V+ LE  G+G   + YRLRD +FSRQRYWGEP+P+    DG + 
Sbjct  381  SDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTST  440

Query  504  llpehclplelpeveKYLPTETGEPPLGNATRWAWDTEKEAVVENSRIDRKTVFPLELNT  563
             +PE  LPL LP      P+ TGE+PL+N T W  +  +E  V   R         E NT
Sbjct  441  AVPESELPLVLPVTKDIRPSGTGESPLANVTDWL-EVTREDGVKGRR---------ETNT  490

Query  564  MPGWAGSSQYFNRYMDPGNDQALVSEEAIGYWEDVDLYIGGSEHATGHLLYSRFWQKFMF  623
            MP WAGSS Y+ RY+DP N + L  EE +  W  VD+Y+GG+EHA  HLLY+RFW+K ++
Sbjct  491  MPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWHKVLY  550

Query  624  DRGWVPKDEYAQKLINQGMILGTSALMYRKSGTQTYLSKGLADREATDAIRVDVGLVNAS  683
            D G VP  E  QKL+NQGMILGTS   YR S      +  +  R+++             
Sbjct  551  DLGVVPTKEPFQKLFNQGMILGTS---YRDSRGALVATDKVEKRDGS-------------  594

Query  684  DALDLAGLKEWQPQYEDAEFVGEDGEFYVDREVEKMSKSKYNVVNPDEICEEYGADALRM  743
                          +    F  E GE  +++   KMSKS  NVVNPD++ E+YGAD+LR+
Sbjct  595  --------------F----FHVETGE-ELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRV  635

Query  744  YEMFLGPLEQSKPWNTAGLSGVYGFLKKFWRLFHQGPDRTFEVLDDTPSAADLKTLHKTI  803
            YEMF+GPL+ S +W+  GL G   FL +  RL+        E+ ++ ++A D K  + T+
Sbjct  636  YEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTK-----EITEENSGALD-KVYNETV  689

Query  804  KKVTEDIEAFSFNTSVSTFMICANELTASNCRSRAVLEPLVVLIEPYAPHMAEELWHQL-  862
            K VTE+++   FNT+++ +M+  N     +         +V LI P+APH++EELW+ L 
Sbjct  690  KAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALT  749

Query  863  GHSESVAREPYPVYDEKYLIESSKEYPISFNGKMRFTLELPLDMSKEEIEKTVLANEKTR  922
            + +ES++  P P YDE  L+E+  E  + ++GK++  L ++ D+S+EE++   LANEK +
Sbjct  750  ASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQ  809

Query  923  QQLAGR  928
             ++AG+
Sbjct  810  AEIAGK  815


 Score =  180 bits (668),  Expect = 3e-46, Method: Compositional matrix adjust.
 Identities = 90/143 (63%), Positives = 116/143 (82%), Gaps = 0/143 (0%)

Query  3    YNFKEIESRWQQYWADNQTFQAEFPSDNPKFYALTMFPYPSGAGLHVGHPLGYIACDIYS  62
            Y+   IE++WQ +WADN+TF++   + +PKFYAL MFPYPSGAGLHVGHP GY A DI S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RFKRHQGYNVLQPMGYDSFGLPAEQYAIQTGQHPAITTEANIARYREQLDALGFSYDWSR  122
            RFKR QG NVL+PMG D+FGLPAEQYA++TG++PA  T  NIA ++ Q++ALGFSYDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVRTSNPGYYRWTQWVFMQLFDS  145
            EV T++P YY+WTQW+F +L++ 
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEK  146

1771) Xcel_2223 in NC_013530


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  450 bits (1696),  Expect = 2e-127, Method: Compositional matrix adjust.
 Identities = 328/737 (45%), Positives = 469/737 (64%), Gaps = 73/737 (9%)

Query  239  LAYVDESPVNWAPGLGTVLANEEVTADGRSERGNFPVFTKALRQWKMRITAYADRLTDDL  298
            LAY  E PVNW   LGT +ANEEV +DG SERG +PV  K++RQW ++ITAYA+RL +DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  299  ELIDWPEKVKSMQRNWIGRSTGANVRFHVVGTTEGDPAGAGGGIEVFTTRPDTLFGATFM  358
            E +DWPE +K MQRNWIG+STGANV F V         +++ ++ VFTTRPDTLFGAT+ 
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKV--------KDTDKDFTVFTTRPDTLFGATYA  259

Query  359  VVSPEHPLLDEVPAAWPDGTKSSWTGGHKSPVeavaayrkaaaaktaverqaDAGKKTGV  418
            V++PEH+L+D +            T+++  +V          +  +  +   +   KTGV
Sbjct  260  VLAPEHALVDAIT-----------TSDQAEAVADYKRQASLKSDLARTDLAKE---KTGV  305

Query  419  FSGHLAVNPLTGTYIPVFTADYVLMGYGTGAIMAVPGGDERDFAFAQAFDLPVIYTVAPE  478
             +G  A+NP+ G  +PV  ADYVL +YGTGAIMAVP+ DERD  FA+ F+L +I  V   
Sbjct  306  WTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDII-PVLEG  364

Query  479  GGLPEGFDEAWTGDGVAVNSPAADAEKAVDLDINGLPVAEAKAATIAWLEAHGIGEGTVT  538
            G + E+   A T DG+ +NS            ++GL  A A A  + WLEA+G+G+  VT
Sbjct  365  GNVEEA---AFTEDGLHINSDF----------LDGLDKASAIAKMVEWLEAEGVGNENVT  411

Query  539  YRLRDWLFSRQRYWGEPFPIV-WDAQDRPVAIPESLLPVDLPDVPDYAPRTFDPEDKDSS  597
            YRLRDWLFSRQRYWGEP+PI+ W+ ++ + A+PES LP+ LP   D  P         ++
Sbjct  412  YRLRDWLFSRQRYWGEPIPIIHWE-DGTSTAVPESELPLVLPVTKDIRP--------SGT  462

Query  598  PEAPLGRNDDWVNITLDLGDGPQQYRRDTNTMPNWAGSCWYYLRYLDPGNAGEGDGTVVD  657
             E+PL+   DW+++T +  DG +  RR+TNTMP+WAGS WYYLRY+DP N+      + D
Sbjct  463  GESPLANVTDWLEVTRE--DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTE----KLAD  515

Query  658  RKLDEYWMGPHHNPTSGPAGGVDLYVGGVEHAVLHLLYARFWHKVLFDLGFVSSIEPFGK  717
              L   W+             VD+YVGG EHAVLHLLYARFWHKVL+DLG V++ EPF K
Sbjct  516  EELLKQWLP------------VDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQK  563

Query  718  LFNQGYIQAYAYRDAQGFPVPAAEVEGDEQTGFTWN-GEAVVREYGKMGKSLKNVVTPDE  776
            LFNQG I + +YRD++G  V++  VE  + + F  + GE + +  +KM+KSLKNVV PD+
Sbjct  564  LFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDD  623

Query  777  MYEAYGADTFRVYEMSMGPLDLSRPWNTRDVVGSQRFLQRLWRNVISEETGEVTVTDEAP  836
            + E YGADT+RVYEM MGPLD S +W+  ++ GS++FL+R+ R + + E     +T+E +
Sbjct  624  VVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKE-----ITEENS  678

Query  837  STETLRAVHRAIADVTAEMEGMRPNTAIAKLITLNNHLTSLPAVPRAAVEPLVLMVAPLA  896
            ++   +  + ++  VT +++ M+ NTAIA+L+ + N       +       +V ++AP+A
Sbjct  679  GALD-KVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFA  737

Query  897  PHLAEELWERL-GHNASLAHEPFPVADPQYLVEDTVTCVVQVQGKVRGRLEVPPSISDAD  955
            PHL+EELW+ L +   S++  P P  D   LVE+ V  VVQ++GKV+++L V+  +S  +
Sbjct  738  PHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREE  797

Query  956  LQAAALAEPNVVKAMDG  972
            LQ  ALA+ +V   + G
Sbjct  798  LQEVALANEKVQAEIAG  814


 Score =  135 bits (494),  Expect = 2e-32, Method: Compositional matrix adjust.
 Identities = 74/149 (50%), Positives = 103/149 (70%), Gaps = 11/149 (7%)

Query  32   IEQRWQDRWEERGTFHAANPAGDLRGPGGAAATGSPYFIMDMFPYPSGAGLHVGHPLGYI  91
            IE +WQ  W +  TF +           G+ A+ + ++ +DMFPYPSGAGLHVGHP GY 
Sbjct  9    IEPKWQAFWADNHTFKT-----------GTDASKPKFYALDMFPYPSGAGLHVGHPEGYT  57

Query  92   ATDVVGRFRRMQGDNVLHALGYDAFGLPAEQYAVQTGQHPRTTTEANIATMKRQLRRMGL  151
            ATD+++RF+R QG+NVLH++G DAFGLPAEQYA++TG++P   T  NIA  KRQ+  +G+
Sbjct  58   ATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGF  117

Query  152  AHDPRRSFATIDPGYVRWTQWIFLQIFDS  180
            + D  R   T DP Y +WTQWIF ++++ 
Sbjct  118  SYDWDREVNTTDPNYYKWTQWIFTKLYEK  146

1772) Poras_0515 in NC_015501


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  450 bits (1695),  Expect = 2e-127, Method: Compositional matrix adjust.
 Identities = 315/744 (43%), Positives = 468/744 (63%), Gaps = 68/744 (9%)

Query  204  LAFLGESVVNWCPELGTVLANDEV-SDGVSERGGYPVVQRKMKQWSLRVSAYAERLLAGL  262
            LA+ +E  VNW  ELGT +AN+EV +DG SERGGYPVV++ M+QW L+++AYAERLL +L
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  263  DQLDWSDALKEMQRNWIGKSVGASVTFKASTAHGELPIEIFTTRPDTLYGVTFMVLAPES  322
            +++DW++++K+MQRNWIGKS GA+VTFK   ++ ++ +  FTTRPDTL+G T+ VLAPE 
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTV--FTTRPDTLFGATYAVLAPEH  265

Query  323  SLVAELTTEEQRAAVEAYLDRTKRRTERERQA-DHSVTGVFTGSYAQHPLTGEQIPIWIS  381
            +LV  +TT +Q  AV  Y  ++  +++  R       TGV TGSYA +P+ G ++P+WI+
Sbjct  266  ALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAINPVNGKEMPVWIA  325

Query  382  DYVLAGYGTGAIMAVPAHDSRDFAFARHFDLPIRQVVLPKGGEASDPSTWSESLDSKEGE  441
            DYVLA+YGTGAIMAVPAHD RD  FA++F+L I  V+   GG+  +++       + +G 
Sbjct  326  DYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL--EGGNVEEAAF------TEDGL  377

Query  442  LINSPLLDGKPVAEAIDYMCHYLDERGLGKKRINYRLRDAIFSRQRYWGEPIPIYYKEGV  501
             INS +LDG   A AI  M + L+  G+G+  + YRLRD +FSRQRYWGEPIPI   E+ 
Sbjct  378  HINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDG  437

Query  502  phtlpldklpltlpEVDKYL-PTESGEPPLGRAKHW---CTEEGY--PYELCTMPGFAGS  555
              T   +     +  V K + P+ +GE+PL+   +W     E+G     E  TMP  AGS
Sbjct  438  TSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVKGRRETNTMPQWAGS  497

Query  556  SAYYLRYMDPQDKSALVSPEANSYWRQVDLYIGGTEHATGHLIYSRFWNKFLYDLGVVCE  615
            S YYLRY+DP++   L   E    W  VD+Y+GG+EHA  HL+Y+RFW+K LYDLGVV  
Sbjct  498  SWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPT  557

Query  616  DEPFKRLVNQGMIQGRSNYVYRIKGTNQFVTYSQREQYDVTQMHVDIHLVQNDILDQEAF  675
             EPF++L NQGMI G S   YR  +   +V+  + E+ D +  HV+      + L+Q + 
Sbjct  558  KEPFQKLFNQGMILGTS---YR-DSRGALVATDKVEKRDGSFFHVET----GEELEQAP-  608

Query  676  RQWRDDLHDATFITEADGSYLCGFAVEKMSKSMFNVINPDEIIEQYGADTLRMYEMFLGP  735
                                       KMSKS+ NV+NPD+++EQYGADTLR+YEMF+GP
Sbjct  609  --------------------------AKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGP  642

Query  736  LEQSKPWDTNGIDGVYRFLKRVWSLYHDGEGQLTVSASAQASREELRTI-HKLIQKITQD  794
            L+ S +W  +G++G  +FL RV  L       +T    ++ +   L  + +  ++ +T++
Sbjct  643  LDASIAWSEEGLEGSRKFLDRVYRL-------ITTKEITEENSGALDKVYNETVKAVTEQ  695

Query  795  IERLSFNTSVSAFMIAVGELQKAQTTSLEVLRPLVILLSPFAPHIAEMLWQEMRsvcsse  854
            ++++ FNT+++ +M+ V   +K +    +  + +V L++PFAPH++E LWQ +       
Sbjct  696  VDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQAL-------  748

Query  855  tlssesivtAAWPQCDESLIAEDSVRYPVSFNGKVRFNLELPAGLSKEQIQEQVLAHADT  914
            T S+ESI   +WP  DES + E+ V   V ++GKV+ +L ++ +LS+E++QE  LA+   
Sbjct  749  TASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKV  808

Query  915  IKWIDGKPLKKVIVVPGRIVNIVL  938
               I GK + KVI VP ++VNIV+
Sbjct  809  QAEIAGKDIIKVIAVPNKLVNIVI  832


 Score =  165 bits (609),  Expect = 1e-41, Method: Compositional matrix adjust.
 Identities = 82/143 (58%), Positives = 106/143 (75%), Gaps = 0/143 (0%)

Query  3    YNHHDIEQSAQRIWQDADIYRVEIDRDKPSYYVLDMFPYPSGAGLHVGHPLGYIASDIYA  62
            Y+H  IE   Q +W D + ++   D  KP +Y LDMFPYPSGAGLHVGHP GY A+DI +
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRLQGYNVLHPMGYDAFGLPAEQYAIQTNRHPEETTRVNIARYREQLDNIGFGFDWSR  122
            R+KR QG NVLHPMG DAFGLPAEQYA++T  +P E T  NIA ++ Q++ +GF++DW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  QVVTCDPEYYKWTQWTFVQLFHH  145
            +V T DP+YYKWTQW F +L++ 
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEK  146

1773) leuS in NC_003228


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  449 bits (1690),  Expect = 5e-127, Method: Compositional matrix adjust.
 Identities = 302/724 (42%), Positives = 462/724 (64%), Gaps = 73/724 (10%)

Query  204  IAYLGNTMVNWCPALGTVLANDEVV-DGVSERGGYPVIQKVMRQWCLRVSAYAQRLLDGL  262
            +AY ++  VNW   LGT +AN+EV+ DG SERGGYPV++K MRQW L+++AYA+RLL++L
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  263  ETVEWTDSLKETQRNWIGRSEGAEMNFKVKDSDIEFTIFTTRADTVFGVTFMVLAPESEL  322
            E V+W +S+K+ QRNWIG+S GA++ FKVKD+D +FT+FTTR+DT+FG T+ VLAPE  L
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  323  VAKLTTPEQKAEVDAYLDRTKKRTERERIA-DRSVSGVFSGSYAINPLTNEPIPVWISDY  381
            V  +TT++Q   V  Y  ++  +++  R    +  +GV +GSYAINP+    +PVWI+DY
Sbjct  268  VDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAINPVNGKEMPVWIADY  327

Query  382  VLAGYGTGAIMAVPAHDSRDYAFAKHFNLEIRPLIEGCDVSEESFDAKEGIMMNSPRPGA  441
            VLA+YGTGAIMAVPAHD RD  FAK+FNL+I P++EG +V E +F + +G+ +NS     
Sbjct  328  VLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEAAF-TEDGLHINSD----  382

Query  442  PEGGLVLNGLTVKEAIAKTKEYIKATGLGRVKVNFRLRDAIFSRQRYWGEPFPVYY-KDG  500
                  L+GL    AIAK  E + A G+G  +V +RLRD +FSRQRYWGEP+P+    DG
Sbjct  383  -----FLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDG  437

Query  501  MPYMIDESCLPLELPEVAKFLPTETGEPPLGHATKWAWDTVNKCVTDNENIDNITIFPLE  560
             +  + ES LPL LP    + P+ TGE+PL++ T W        VT ++ +        E
Sbjct  438  TSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWL------EVTREDGVKGRR----E  487

Query  561  LNTMPGFAGSSAYYLRYMDPRNHEALVSPAVDQYWKNVDLYVGGTEHATGHLIYSRFWNK  620
             NTMP  AGSS YYLRY+DP+N E L    + + W  VD+YVGG+EHA  HL+Y+RFW+K
Sbjct  488  TNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWHK  547

Query  621  FLHDWGISVAEEPFQKLVNQGMIQGRSNFVYRIKDTNTFVSLNLKDQYEVTPIHVDVNIV  680
             L D G+  + EPFQKL NQGMI G S   YR     ++V+ +  ++ + + +HV+    
Sbjct  548  VLYDLGVVPTKEPFQKLFNQGMILGTS---YR-DSRGALVATDKVEKRDGSFFHVE----  599

Query  681  SNDILDLEAFKAWRPEYETAEFILEDGKYICGWAVEKMSKSMFNVVNPDMIVEKYGADTL  740
            + + L+  +                           KMSKS+ NVVNPD +VE+YGADTL
Sbjct  600  TGEELEQAP--------------------------AKMSKSLKNVVNPDDVVEQYGADTL  633

Query  741  RMYEMFLGPVEQSKPWDTNGIDGVHRFIKKFWSLFYDRNGEYLVKDEPATKEELKALHKL  800
            R+YEMF+GP++ S +W  +G++G ++F+ +   L+  ++   +  +++++ +  K  +  
Sbjct  634  RVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKE---ITEENSGALD--KVYNET  688

Query  801  IKKVTGDIEQFSYNTSVSAFMICVNELSSLKCNKKEVL-----EQLIVVLAPFAPHVCEE  855
            +K VT +++Q  +NT+++ +M+ VN       NK + L       ++ ++APFAPH+ EE
Sbjct  689  VKAVTEQVDQMKFNTAIAQLMVFVNA-----ANKEDKLFSDYAKGFVQLIAPFAPHLGEE  743

Query  856  LWDTLGSTT-SVCDAQWPAFNEQYLVEDTVNYTISFNGKARFNMEFPANAASDAIQATVL  914
            LW++L ++  S+    WP+++E  LVE+ V+  + ++GK + ++  + + + + +Q   L
Sbjct  744  LWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVAL  803

Query  915  ADER  918
            A+E+
Sbjct  804  ANEK  807


 Score =  173 bits (641),  Expect = 5e-44, Method: Compositional matrix adjust.
 Identities = 86/142 (61%), Positives = 113/142 (80%), Gaps = 0/142 (0%)

Query  3    YNFREIEKKWQKIWVDNHTYQVNEDASKQKFYVLNMFPYPSGAGLHVGHPLGYIASDIYA  62
            Y+   IE KWQ +W DNHT++   DASK KFY L+MFPYPSGAGLHVGHP GY A+DI +
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRLQGFNVLNPMGYDAYGLPAEQYAIQTGQHPAITTVNNINRYREQLDKIGFSFDWNR  122
            R+KR QG NVL+PMG DA+GLPAEQYA++TG++PA  T +NI  ++ Q++ +GFS+DW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EIRTCDPEYYHWTQWAFIKMFN  144
            E+ T DP+YY WTQW F K+++
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYE  145

1774) Slin_1712 in NC_013730


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  448 bits (1686),  Expect = 1e-126, Method: Compositional matrix adjust.
 Identities = 306/729 (42%), Positives = 454/729 (63%), Gaps = 75/729 (10%)

Query  206  LTFLADAVVNWCPALGTVLANDEV-KDGVSERGGYPVEQKLMRQWMMRITAYADRLLTGL  264
            L++ A+  VNW   LGT +AN+EV  DG SERGGYPV +K MRQWM++ITAYA+RLL +L
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  265  DTIDWTESLKEQQRNWIGKSVGASVKFPIAEVDENASASFIEVFTTRVDTIYGVTFMVLA  324
            + +DW ES+K+ QRNWIGKS GA+V F + + D +     + VFTTR DT++G T+ VLA
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKD-----FTVFTTRPDTLFGATYAVLA  262

Query  325  PEHELVSTLTTPEQKEAVEAYVNAAKLRSERDRMADTKVISGVFTGSYCVNPFNDEKVPI  384
            PEH LV ++TT++Q EAV  Y   A L+S+  R   +K  +GV TGSY +NP N+  +P+
Sbjct  263  PEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAINPVNGKEMPV  322

Query  385  YLADYVLAGYGTGAVMAVPSGDQRDWNFAKHFNLPIVPILDSQKAVEEQADNTKEGHYIN  444
             +ADYVLA+YGTGA+MAVP+ D+RDW+FAK+FNL I+P+L++ +   E+A  T +G  IN
Sbjct  323  WIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNV--EEAAFTEDGLHIN  380

Query  445  SGMINGMTYKEATATLITWLEERGLGKGKVNYRMRDAVFSRQRYWGEPVPVYFKEGGSTG  504
            S+ ++G+    A A ++ WLE  G+G+ +V YR+RD +FSRQRYWGEP+P+   E+G++ 
Sbjct  381  SDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTST  440

Query  505  KLPYLIDESDLPLELPAVDKYLPTETGEPPLGRAEDW-------KYKGKYEYELSTMPGW  557
             +P    ES+LPL LP      P+ TGE+PL+   DW         KG+   E +TMP W
Sbjct  441  AVP----ESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVKGR--RETNTMPQW  494

Query  558  AGSSWYWYRYMDPQNNDEFASKDAIDYWQNVDLYIGGTEHATGHLLYSRFWNKFLKDRGY  617
            AGSSWY  RY+DP+N + +A  + +  W  VD+Y+GG+EHA  HLLY+RFW+K L D G 
Sbjct  495  AGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGV  554

Query  618  VPQEEPFKKLINQGMIQGRSMLVYRVKDSEGQGKTPVFVSFGLKNQYETTELHVDVNIVE  677
            VP  EPF+KL+NQGMI G S   YR    +++G                        +V 
Sbjct  555  VPTKEPFQKLFNQGMILGTS---YR----DSRG-----------------------ALVA  584

Query  678  NDVLDTEAFKHWLPDYKNAEFILENGKYVCGSVVEKMSKRYYNVVNPDDIAERYGADVLR  737
             D ++           +++ F+  +          KMSK   NVVNPDD+ E+YGAD LR
Sbjct  585  TDKVEK----------RDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLR  634

Query  738  LYEMFLGPLEQAKPWNTNGIDGVYRFIRKFWRLFYKDTAAGASDEGANQWIVTDEQPTPA  797
            +YEMF+GPL+ + +W+ +G++G  +F+ +  RL+                 +T+E++ + 
Sbjct  635  VYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKE-------------ITEENSGAL  681

Query  798  ELKVLHKTIKKTEEDIELYSFNTSVSSFMICVNELATLNCHKRAVLQDLVLLLSPYAPHI  857
            + KV + T+K   E+++   FNT+++ +M+ VN     +       +++V L++P+APH+
Sbjct  682  D-KVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHL  740

Query  858  TEELWAALGNEPGSISSAEFPKFNPNYLIEDSFEYPIQINGKVRTTISFAIDRAPTEIER  917
             EELW AL     SIS    P ++ + L+E+  E  +QI+GKV++ +  A D +  E++ 
Sbjct  741  GEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQE  800

Query  918  EVLADEIVQ  926
              LA+E VQ
Sbjct  801  VALANEKVQ  809


 Score =  181 bits (672),  Expect = 2e-46, Method: Compositional matrix adjust.
 Identities = 88/141 (63%), Positives = 114/141 (81%), Gaps = 0/141 (0%)

Query  4    YNHRETEQKWQRFWDENHTYKPAVTTDRPKYYVLDMFPYPSGAGLHVGHPLGYIASDIVS  63
            Y+H   E KWQ FW +NHT+K +  + +PK+Y LDMFPYPSGAGLHVGHP GY A+DI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  64   RYKRLKGYNVLHPMGFDSFGLPAEQYAIQTGQHPAVTTEQNLTRYIEQLKNIGFSYDWSR  123
            R+KR +G NVLHPMG D+FGLPAEQYA++TG++PA  T +N++ +  Q++ +GFSYDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  124  EVRTSDPSYYKWTQWIFMELF  144
            EV T+DP+YYKWTQWIF  L+
Sbjct  124  EVNTTDPNYYKWTQWIFTKLY  144

1775) AL1_17720 in NC_021030


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  448 bits (1689),  Expect = 6e-127, Method: Compositional matrix adjust.
 Identities = 307/703 (44%), Positives = 458/703 (66%), Gaps = 52/703 (7%)

Query  204  LAFRADTQVNWCPKLGTVLANDEV-HDGLSVRGGYPVEQKRMKQWLLRVTAYAQRMLDGL  262
            LA+ A+  VNW   LGT +AN+EV  DG S RGGYPV +K M+QW+L++TAYA+R+L++L
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  263  DKLEWSDSLKEIQRNWIGRSEGAQVFFDIENSDRKLEIFTTRPDTIFGVTFMVIAPEHEW  322
            + ++W++S+K++QRNWIG+S GA+V F + ++D+ + +FTTRPDT+FG T+ V+APEH  
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  323  VGELTTPENKAAVEEYIRQTKKRSERDRIADTKRVSGVATGSYAINPFTNKAIPIYISDY  382
            V+ +TT+++  AV +Y RQ+  +S+  R   +K  +GV TGSYAINP   K +P+ I+DY
Sbjct  268  VDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAINPVNGKEMPVWIADY  327

Query  383  VLSGYGTGAIMAVPAHDSRDWAFARHFGLEIVPVVEGGDIEKESYDAKTGKVINSDFLNG  442
            VL++YGTGAIMAVPAHD RDW FA++F L+I+PV+EGG++E  ++ +  G  INSDFL+G
Sbjct  328  VLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEAAF-TEDGLHINSDFLDG  386

Query  443  MDVKEAIQVMFAEVEKRGLGKKLVNYRLRDAIFSRQRYWGEPFPIYY-KNDTAYPLAEDK  501
            +D   AI  M   +E  G+G+  V YRLRD +FSRQRYWGEP+PI    ++T+ +++E  
Sbjct  387  LDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESE  446

Query  502  LPLELPPIENFGPTAEGEPPLARVKGW---ATPEGC--PYELSTMPGFAGSSAYYLRYMD  556
            LPL LP   ++ P++ GE+PLA V +W   +  +G     E +TMP  AGSS YYLRY+D
Sbjct  447  LPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYID  506

Query  557  PHNDKALVGKEADEYWRNVDLYVGGIEHATGHLMYSRFWNMFLYDLGCVCEEEPFRKLVN  616
            PHN   L + E    W  VD+YVGG EHA  HL+Y+RFW+  LYDLG V   EPF+KL N
Sbjct  507  PHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFN  566

Query  617  QGMIQGRSNFVYRIVGTNRFVSLGLKDQYETQALYVDVNIVRNDILDLDAFRAWMPEYKD  676
            QGMI G S   YR                ++++  V  + V +               +D
Sbjct  567  QGMILGTS---YR----------------DSRGALVATDKVEK---------------RD  592

Query  677  AEFI-LEDGKYVCGWAIEKMSKSFYNVVNPDYIVDNYGADTLRMYEMFLGPLEQSKPWDT  735
            + F+ +E G  +   A  KMSKS+ NVVNPD +V++YGADTLR+YEMF+GPL+ S +W  
Sbjct  593  GSFFHVETGEELEQ-APAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSE  651

Query  736  NGIDGVHKflrrfwrlffdrdGQLCVTDEKATEQELRTLHKTIKKVSEDIENFSFNTSVA  795
            +G++G +KFL R  RL+  ++    +T+E++   + +  + T+K V+E++++  FNT++A
Sbjct  652  EGLEGSRKFLDRVYRLITTKE----ITEENSGALD-KVYNETVKAVTEQVDQMKFNTAIA  706

Query  796  AFMICLNELGECSK--REVLEPLTVLLAPFAPHIAEELWAAL-GHTESVCTASYPVCDET  852
             +M+ +N      K   +    +  L+APFAPH++EELW AL +  ES+   + P  DE+
Sbjct  707  QLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDES  766

Query  853  HLLRNSFEYPVSVNGKLRFRKEYAASMTPAEIQADVVTAPEAQ  895
             L+ N  E  V ++GK++ +   A  ++  E+Q   ++    Q
Sbjct  767  KLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQ  809


 Score =  174 bits (645),  Expect = 2e-44, Method: Compositional matrix adjust.
 Identities = 90/141 (64%), Positives = 113/141 (81%), Gaps = 0/141 (0%)

Query  3    YNFKEIEAKWQSRWRADKTYKVETDPSRPKFYVLDMFPYPSGAGLHVGHPLGYIASDIYS  62
            Y+   IE+KWQ+ W  + T+K  TD+S+PKFY LDMFPYPSGAGLHVGHP GY A+DI S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRLKGFNVLHPMGYDAFGLPAEQYAIQTGQHPAVTTEQNIARYREQLDKIGFSFDWDR  122
            R+KR +G NVLHPMG DAFGLPAEQYA++TG++PA  T +NIA ++ Q++ +GFS+DWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVRTCDPGYYKWTQWAFLEMF  143
            EV T DP YYKWTQW F  ++
Sbjct  124  EVNTTDPNYYKWTQWIFTKLY  144

1776) leuS in NC_016776


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  448 bits (1689),  Expect = 6e-127, Method: Compositional matrix adjust.
 Identities = 302/724 (42%), Positives = 461/724 (64%), Gaps = 73/724 (10%)

Query  204  IAYLGNTMVNWCPALGTVLANDEVV-DGVSERGGYPVIQKVMRQWCLRVSAYAQRLLDGL  262
            +AY ++  VNW   LGT +AN+EV+ DG SERGGYPV++K MRQW L+++AYA+RLL++L
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  263  ETVEWTDSLKETQRNWIGRSEGAEMNFKVKDSDIEFTIFTTRADTVFGVTFMVLAPESEL  322
            E V+W +S+K+ QRNWIG+S GA++ FKVKD+D +FT+FTTR+DT+FG T+ VLAPE  L
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  323  VAKLTTPEQKAEVDAYLDRTKKRTERERIA-DRSVSGVFSGSYAINPLTNEPIPVWISDY  381
            V  +TT++Q   V  Y  ++  +++  R    +  +GV +GSYAINP+    +PVWI+DY
Sbjct  268  VDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAINPVNGKEMPVWIADY  327

Query  382  VLAGYGTGAIMAVPAHDSRDYAFAKHFNLEIRPLIEGCDVSEESFDAKEGIMMNSPRPGA  441
            VLA+YGTGAIMAVPAHD RD  FAK+FNL+I P++EG +V E +F + +G+ +NS     
Sbjct  328  VLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEAAF-TEDGLHINSD----  382

Query  442  PEGGLVLNGLTVKEAIAKTKEYIKATGLGRVKVNFRLRDAIFSRQRYWGEPFPVYY-KDG  500
                  L+GL    AIAK  E + A G+G  +V +RLRD +FSRQRYWGEP+P+    DG
Sbjct  383  -----FLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDG  437

Query  501  MPYMIDESCLPLELPEVAKFLPTETGEPPLGHATKWAWDTVNKCVTDNENIDNITIFPLE  560
             +  + ES LPL LP    + P+ TGE+PL++ T W        VT ++ +        E
Sbjct  438  TSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWL------EVTREDGVKGRR----E  487

Query  561  LNTMPGFAGSSAYYLRYMDPRNHEALVSPAVDQYWKNVDLYVGGTEHATGHLIYSRFWNK  620
             NTMP  AGSS YYLRY+DP+N E L    + + W  VD+YVGG+EHA  HL+Y+RFW+K
Sbjct  488  TNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWHK  547

Query  621  FLHDWGISVAEEPFQKLVNQGMIQGRSNFVYRIKDTNTFVSLNLKDQYEVTPIHVDVNIV  680
             L D G+  + EPFQKL NQGMI G S   YR     ++V+ +  ++ + + +HV+    
Sbjct  548  VLYDLGVVPTKEPFQKLFNQGMILGTS---YR-DSRGALVATDKVEKRDGSFFHVE----  599

Query  681  SNDILDLEAFKAWRPEYETAEFILEDGKYICGWAVEKMSKSMFNVVNPDMIVEKYGADTL  740
            + + L+  +                           KMSKS+ NVVNPD +VE+YGADTL
Sbjct  600  TGEELEQAP--------------------------AKMSKSLKNVVNPDDVVEQYGADTL  633

Query  741  RMYEMFLGPVEQSKPWDTNGIDGVHRFIKKFWSLFYDRNGEYLVKDEPATKEELKALHKL  800
            R+YEMF+GP++ S +W  +G++G ++F+ +   L+  ++   +  +++++ +  K  +  
Sbjct  634  RVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKE---ITEENSGALD--KVYNET  688

Query  801  IKKVTGDIEQFSYNTSVSAFMICVNELSSLKCNKKEVL-----EQLIVVLAPFAPHVCEE  855
            +K VT +++Q  +NT+++ +M+ VN       NK + L       ++ ++APFAPH+ EE
Sbjct  689  VKAVTEQVDQMKFNTAIAQLMVFVNA-----ANKEDKLFSDYAKGFVQLIAPFAPHLGEE  743

Query  856  LWDTLGNTT-SVCDAQWPAFNEQYLVEDTVNYTISFNGKARFNMEFPANAASDAIQATVL  914
            LW++L  +  S+    WP+++E  LVE+ V+  + ++GK + ++  + + + + +Q   L
Sbjct  744  LWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVAL  803

Query  915  ADER  918
            A+E+
Sbjct  804  ANEK  807


 Score =  173 bits (641),  Expect = 5e-44, Method: Compositional matrix adjust.
 Identities = 86/142 (61%), Positives = 113/142 (80%), Gaps = 0/142 (0%)

Query  3    YNFREIEKKWQKIWVDNHTYQVNEDASKQKFYVLNMFPYPSGAGLHVGHPLGYIASDIYA  62
            Y+   IE KWQ +W DNHT++   DASK KFY L+MFPYPSGAGLHVGHP GY A+DI +
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRLQGFNVLNPMGYDAYGLPAEQYAIQTGQHPAITTVNNINRYREQLDKIGFSFDWNR  122
            R+KR QG NVL+PMG DA+GLPAEQYA++TG++PA  T +NI  ++ Q++ +GFS+DW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EIRTCDPEYYHWTQWAFIKMFN  144
            E+ T DP+YY WTQW F K+++
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYE  145

1777) leuS in NC_018142


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  448 bits (1688),  Expect = 8e-127, Method: Compositional matrix adjust.
 Identities = 334/740 (46%), Positives = 484/740 (66%), Gaps = 66/740 (8%)

Query  213  LAYLSEAPVNWCPGLGTVLANEEVTNEGRSEIGNFPVFKRNMSQWMLRITAYAERLLADL  272
            LAY +E PVNW   LGT +ANEEV  +G SE G +PV ++ M QWML+ITAYAERLL DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  273  DKLDWPDKVKAMQRNWIGRSEGARVFFTEAASGERIEVFTTRPDTLFGATFMVLAPEHHL  332
            + +DWP+ +K MQRNWIG+S GA V F    ++  + VFTTRPDTLFGAT+ VLAPEH L
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  333  ADGAASEWPEGTDPAWTGGHASPaeavaayraeverrTDADRSGDDKEKTGLFTGRFAIN  392
             D+ ++              +  AEAVA Y+ +   ++D  R++  KEKTG+ TG +AIN
Sbjct  268  VDAITT--------------SDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAIN  313

Query  393  PVNGQRVPIFIADYVTLGYGTGAVMAVPSGDQRDWEFAKAYNLPIVETVIPCSEHDGNSA  452
            PVNG+ +P+ IADYV  +YGTGA+MAVP+ D+RDWEFAK +NL I+  +   + +  ++A
Sbjct  314  PVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLE--GGNVEEAA  371

Query  453  WTGDGEVINSANPEISLNGMNVSDAKTAITEWLEAKGLGEATVNYRLRDWLFSRQRYWGE  512
             T DG  INS      L+G++ + A + + EWLEA G+G+  V YRLRDWLFSRQRYWGE
Sbjct  372  FTEDGLHINSD----FLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGE  427

Query  513  PFPIVYDETGlpialpeemlpielpeVTDYSPKAMDPEDRNSDPVPPLARATDWTSVELD  572
            P+PI+  E G + A+PE  LP+ LP   D  P + +         +PLA  TDW  +E+ 
Sbjct  428  PIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGE--------SPLANVTDW--LEVT  477

Query  573  LGDGKKVYRRELNVMPQWAGSCWYEMRYLDPANHDRFVGEEVERYWMGPRgegdvggvdl  632
              DG K  RRE N MPQWAGS WY +RY+DP N +++ +EE+ + W+          VD+
Sbjct  478  REDGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLP---------VDI  527

Query  633  yvggveHAVLHLLYARFWHKVLFDLGFVSSAEPFRRLFNQGYIQAYAYRDSRGQTVPAAE  692
            YVGG EHAVLHLLYARFWHKVL+DLG V++ EPF++LFNQG I + +YRDSRG  V++  
Sbjct  528  YVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDK  587

Query  693  VEAHGE-------GQEMTWTWQDQFVKREYGKMGKSLKNIVSPDEMYEAYGADTFRLYEM  745
            VE ++        G+E+          +  +KM+KSLKN+V+PD++ E YGADT+R+YEM
Sbjct  588  VEKRDGSFFHVETGEEL---------EQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEM  638

Query  746  GMGPLAQSKPWETRAVVGSQRFLQRLWRNVVDEETGDLVTRDTDIDEATLHAL-HKTIDA  804
             MGPL  S +W   ++ GS++FL+R+ R +   E        T+ + ++L+ + + T+ A
Sbjct  639  FMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEI-------TEENSGALDKVYNETVKA  691

Query  805  VNKDYENLSFNTAIARLTEYNTVLTALKVVPRAAVEPLVLMVAPLAPHIAEELWHRL-GH  863
            V  + +++ FNTAIA+L  +         +       +V ++AP+APH++EELW+ L + 
Sbjct  692  VTEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTAS  751

Query  864  DQSLAHEPFPVADPELVAEDTITAVVQVRGKLRAQLEVSASITEDELRELALAHPRIVKE  923
            ++S++  P P  D   + E+ +  VVQ++GK++A+L V+  ++ +EL+E+ALA+ ++  E
Sbjct  752  GESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAE  811

Query  924  IP-NGVRKVIVRAPKLVNVV  942
            I+ +++ KVI  + KLVN+V
Sbjct  812  IAGKDIIKVIAVPNKLVNIV  831


 Score =  130 bits (475),  Expect = 6e-31, Method: Compositional matrix adjust.
 Identities = 73/150 (49%), Positives = 103/150 (69%), Gaps = 11/150 (7%)

Query  14   GEIEAHWQDHWETEGTFHAPNPAGPWAEPEKIDSRGEKLFVLDMFPYPSGAGLHVGHPLG  73
              IE+ WQ  W  + TF +             D+   K++ LDMFPYPSGAGLHVGHP G
Sbjct  7    TAIEPKWQAFWADNHTFKTGT-----------DASKPKFYALDMFPYPSGAGLHVGHPEG  55

Query  74   YIATDTFARFNRMKGRNVLHALGYDAFGLPAEQYAVQSGQHPRVTTEHNIAIMRRQLRRL  133
            Y ATD ++RF+R +G+NVLH++G DAFGLPAEQYA+++G++P   T +NIA  +RQ+  L
Sbjct  56   YTATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINAL  115

Query  134  GLAHDPRRSVATVDVEFYRWTQWIFLQIFN  163
            G++ D  R V T D ++Y+WTQWIF ++++
Sbjct  116  GFSYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1778) Celgi_1211 in NC_015671


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  447 bits (1683),  Expect = 2e-126, Method: Compositional matrix adjust.
 Identities = 333/733 (46%), Positives = 480/733 (66%), Gaps = 52/733 (7%)

Query  243  LAYVSETPVNWCPGLGTVLANEEVTSDGRSERGNFPVFQRSLRQWNMRITAYADRLADDL  302
            LAY +E PVNW   LGT +ANEEV +DG SERG +PV ++++RQW ++ITAYA+RL +DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  303  DHIDWPEKVKSMQRNWIGRSSGARVRFAV-EGGSQVEVFTTRPDTLFGATFMVVAPEHPL  361
            +++DWPE +K MQRNWIG+S+GA V F V + + +  VFTTRPDTLFGAT+ V+APEH+L
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  362  LDEVPPSWPDGTHAAWTGGHaspaeavaayraeaaaktaverqaDAGRKTGVFTGHLAIN  421
            +D +            T+++A +        +  +  +  +   +   KTGV TG  AIN
Sbjct  268  VDAIT-----------TSDQAEAVADYKRQASLKSDLARTDLAKE---KTGVWTGSYAIN  313

Query  422  PVNGQPLPVFTADYVLMGYGTGAIMAVPGGDERDFAFAQAYELPVV-YTTAGDVTDAART  480
            PVNG+ +PV  ADYVL +YGTGAIMAVP+ DERD  FA+ ++L ++    +G+V +AA T
Sbjct  314  PVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEAAFT  373

Query  481  GDGVVINSSNDELSLDGLGVAEAKERMIAWLTAAGIGEGTITYRLRDWLFSRQRYWGEPF  540
             DG+ INS      LDGL+ A A  +M+ WL A G+G+  +TYRLRDWLFSRQRYWGEP+
Sbjct  374  EDGLHINSD----FLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPI  429

Query  541  PVVYDEHdlpialpaellpvalpdvpdYAPRTFdpedsasspeppLGRNDEWVTVTLDLG  600
            P++  E++ + A+P   LP+ LP   D  P          + E+PL+   +W+ VT +  
Sbjct  430  PIIHWEDGTSTAVPESELPLVLPVTKDIRPSG--------TGESPLANVTDWLEVTRE--  479

Query  601  DGPRQYRRDTNTMPNWAGSCWYYLRYLDPTSDEVLVDPELERFWMGPGHNGDPADTVGGV  660
            DG +  RR+TNTMP+WAGS WYYLRY+DP + E L D EL + W+              V
Sbjct  480  DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLP-------------V  525

Query  661  DLYVGGVEHAVLHLLYARFWHKVLFDLGHVSGGEPFHQLFNQGYIQAYAYTDARGVHVPA  720
            D+YVGG EHAVLHLLYARFWHKVL+DLG V+  EPF++LFNQG I + +Y D+RG  V++
Sbjct  526  DIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVAT  585

Query  721  DEVVEDEASPTGFTWQGEPVNREYGKMGKSLKNMVTPDEMYAEYGADTLRVYEMSMGPLD  780
            D V   ++S       GE +++  +KM+KSLKN+V PD++  +YGADTLRVYEM MGPLD
Sbjct  586  DKVEKRDGSFFHVE-TGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLD  644

Query  781  LSRPWETRAVVGSQRFLQRLWRNVVSEADGTLVVSEDAPSDETSRVLHRTIADVTEDMAA  840
             S +W   ++ GS++FL+R+ R + +       ++E+ ++    +V + T+  VTE++  
Sbjct  645  ASIAWSEEGLEGSRKFLDRVYRLITTKE-----ITEENSG-ALDKVYNETVKAVTEQVDQ  698

Query  841  MRINTAIAKLIVLNNHLTTLPAAPRAAVEALVLMTAPIAPHVAEEIWARL-GHERSLAYE  899
            M++NTAIA+L+V+ N              ++V + AP+APH++EE+W  L +   S++Y 
Sbjct  699  MKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYV  758

Query  900  PYPVADPAFLVEETVTCVFQVAGKVRGRAEVAVdssddalrelaladaGVQRALDGRGVR  959
            P P  D + LVE+ V  V Q+ GKV+++  VA D S + L+E+ALA+  VQ  + G+++ 
Sbjct  759  PWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDII  818

Query  960  TVIVRAPRLVNVV  972
             VI  + +LVN+V
Sbjct  819  KVIAVPNKLVNIV  831


 Score =  132 bits (483),  Expect = 1e-31, Method: Compositional matrix adjust.
 Identities = 74/150 (50%), Positives = 104/150 (70%), Gaps = 13/150 (8%)

Query  31   IELRWQDEWQERGTFHAANPTGSLTDGDGRHADPSRRSFFVMDMFPYPSGAGLHIGHPLG  90
            IE +WQ  W +  TF ++             +D+S+  F+ +DMFPYPSGAGLH+GHP G
Sbjct  9    IEPKWQAFWADNHTFKTG-------------TDASKPKFYALDMFPYPSGAGLHVGHPEG  55

Query  91   YIATDVVARFRRMQGDNVLHALGFDAFGLPAEQYAVQTGQHPRVTTEANIAIMQRQLRRL  150
            Y ATD+++RF+R QG+NVLH++G DAFGLPAEQYA++TG++P   T  NIA  +RQ+  L
Sbjct  56   YTATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINAL  115

Query  151  GLAHDPRRSFATIDPDYVRWTQWIFLQIFG  180
            G++ D  R   T DP+Y +WTQWIF +++ 
Sbjct  116  GFSYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1779) leuS in NC_009921


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  447 bits (1682),  Expect = 3e-126, Method: Compositional matrix adjust.
 Identities = 346/778 (45%), Positives = 481/778 (62%), Gaps = 96/778 (12%)

Query  241   LTYISEELVNWCPGLGTVLANEEVTPEGRSDIGNYPVYRRPLRQWMMRITAYADRLMSDL  300
             L+Y +E  VNW   LGT +ANEEV P+G S+ G YPV R+P+RQWM++ITAYA+RL+ DL
Sbjct  148   LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  301   DLVDWPDSIKHMQRNWIGPSDGATVRFStvtgagdtagaggvdapvgpapIDVEVYTTRP  360
             + VDWP+SIK+MQRNWIG S GA V F                        D  V+TTRP
Sbjct  208   EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDK-----------------DFTVFTTRP  250

Query  361   DTLPGATFLVLAPEHPLVDALTATSWPADTPAGWRFAQERPAGVTDGEWTPQaavdayra  420
             DTL GAT+ VLAPEH+LVDA+T++   A++ A+ +    R A++                
Sbjct  251   DTLFGATYAVLAPEHALVDAITTSD-QAEAVADYK----RQASLK---------------  290

Query  421   faarrSDRQRGGTEIDRTGVFTGTYVRNPVGGGVIPVFLADYVLLGYGTGAIMAVPAHDE  480
                  SD  R +   ++TGV TG+Y  NPV G  +PV +ADYVL +YGTGAIMAVPAHDE
Sbjct  291   -----SDLARTDLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDE  345

Query  481   RDFSFAQEFGLPIPAVLEPDEAWLAERDLAAGAPASSWPEAFSGEGSYLAGATDRPVLAG  540
             RD  FA++F L I +VLE            +G    +   AF+ +G  + +      L G
Sbjct  346   RDWEFAKQFNLDIIPVLE------------GGNVEEA---AFTEDGLHINSD----FLDG  386

Query  541   LSKADAIKTTISWLEDAGRGRATRSYRLRDWLFSRQRYWGEPFPIVFDDDGMPRAvpeeq  600
             L KA AI   + WLE  G G    +YRLRDWLFSRQRYWGEP+PI+  +DG + AVPE +
Sbjct  387   LDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESE  446

Query  601   lpvelpeMTDFRPKAMADDDESEPVPPLARATEWTTVTLDLGDGPRGYRRELNTMPQWAG  660
             LP+ LP   D+RP + ++       +PLA  T+W  VT +  DG +G RRE NTMPQWAG
Sbjct  447   LPLVLPVTKDIRPSGTGE-------SPLANVTDWLEVTRE--DGVKG-RRETNTMPQWAG  496

Query  661   SCWYYLRYLDPTNSERFVDPAVERYWMHSERGPAgdggvdlyvggvEHAVLHLLYARFWH  720
             S WYYLRY+DP N+E++ D  + + W+  +          +YVGG EHAVLHLLYARFWH
Sbjct  497   SSWYYLRYIDPHNTEKLADEELLKQWLPVD----------IYVGGAEHAVLHLLYARFWH  546

Query  721   KVLYDLGLVSTREPFKRLYNQGYIQADAFTDERGMYVPATEVVQGADGSFSH--EGAPVN  778
             KVLYDLG+V+T+EPF++L+NQG I + ++ D RG  V AT+ V+  DGSF H   G  ++
Sbjct  547   KVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALV-ATDKVEKRDGSFFHVETGEELE  605

Query  779   RRSGKMGKSLKNSVSPDEMYDSYGADTLRVYEMAMGPLDAHRPWRTDDIVGSYRFLQRLW  838
             + ++KM+KSLKN V+PD++ + YGADTLRVYEM MGPLDA  +W  +++ GS +FL+R+ 
Sbjct  606   QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVY  665

Query  839   RNIIDEGTGEPRVRAAALDDETAQALHRTILAVRADYAELRFNTAVARLIELTNLASKRF  898
             R I      E    ++ALD    +  + T+ AV  +  +++FNTA+A+L+ + N A+K  
Sbjct  666   RLITTKEITEE--NSGALD----KVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKE-  718

Query  899   GAGLDGPPRELAEALVLMAAPLAPHIAEELWTRLGHTG-SVCAVPFPEGDESLAAAATVR  957
                 D    + A ++V + AP+APH++EELW  L  +G S+  VP P  DES      V 
Sbjct  719   ----DKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVE  774

Query  958   LPVQVNGKVRFTIDVPADADEAAVRAVLEAHADYTRHTSGRTIKRLIVVPGRIVNIAL  1015
             + VQ++GKV+  + V+ D     ++ V  A+     + +G+ I ++I VP ++VNI +
Sbjct  775   IVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVI  832


 Score =  134 bits (492),  Expect = 3e-32, Method: Compositional matrix adjust.
 Identities = 74/151 (50%), Positives = 102/151 (68%), Gaps = 11/151 (7%)

Query  33   AEIERHWQQRWLREGTFESPNPTGPLSEGFEAVRGRDPFYVLDMFPYPSGTGLHVGHPLG  92
            + IE  WQ  W  + TF +   ++           +  FY LDMFPYPSG+GLHVGHP G
Sbjct  7    TAIEPKWQAFWADNHTFKTGTDAS-----------KPKFYALDMFPYPSGAGLHVGHPEG  55

Query  93   YIGSDVFARFLRMTGRHVLHTFGYDAFGLPAEQYAINTGQHPRVTTEANIANMRRQLSRL  152
            Y ++D+++RF R  G++VLH  G DAFGLPAEQYA++TG++P   T  NIAN +RQ++ L
Sbjct  56   YTATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINAL  115

Query  153  GLGHDTRREIATTDTAYYRWTQWIFLKIFDS  183
            G++ D  RE+ TTD  YY+WTQWIF K+++ 
Sbjct  116  GFSYDWDREVNTTDPNYYKWTQWIFTKLYEK  146

1780) leuS in NC_000918


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  445 bits (1676),  Expect = 5e-126, Method: Compositional matrix adjust.
 Identities = 279/598 (47%), Positives = 382/598 (64%), Gaps = 38/598 (6%)

Query  5    FNPREIEKKWQKRWEEAGVFK-AQEGKPNKFYVLEMFPYPSGR-IHMGHVRNYTIGDAIA  62
            ++   IE KWQ  W +   FK + ++   KFY L+MFPYPSG  +H+GH   YT  D ++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYLKMRGKNILHPMGWDAFGLPAENAAIKHGIHPAKWTYENIDYMKKQLKILGFSYDWDR  122
            R+ + +G N+LHPMGWDAFGLPAE+ A+  G +PA  T ENI   K+Q++ LGFSYDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EIATCDPEYYKWNQWIFLKMLERGIAYRKTAKVNWCPHDQTVLANEQVI-EGKCWRCGTP  181
            E+ T DP+YYKW QWIF K+ E+G+AY     VNW  +  T +ANE+V+ +G   R G P
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  182  IVQKEVPSWFLRITAYADRLLEDLKKLEGKWPERVIAQQRNWIGRSEGALIRFYVEIEEP  241
            +V+K +  W L+ITAYA+RLLEDL  ++  WPE +   QRNWIG+S GA + F V   + 
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEVD--WPESIKDMQRNWIGKSTGANVTFKVKDTDK  241

Query  242  EKFLNCVPeelketllkekRIYIDVFTTRPDTVFGATFVVLAPEHPLVPVLACIGERLGN  301
            +                     + VFTTRPDT+FGAT+ VLAPEH+LV  ++  ++  + 
Sbjct  242  D---------------------FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAV  280

Query  302  ACYSDVENFVEKMKKMSTRERTMEEDKEGVFLGVYATNPANGEKIPVWSANYVLYEYGTG  361
            A Y    ++   + +       +  +K GV  G YA NP NG  +PVW A+YVL  YGTG
Sbjct  281  ADYKRQASLKSDLARTD-----LAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTG  335

Query  362  AIMCVPAHDQRDWEFAKKYDLPIKVVVKPEGAWDFEKGAYEGKGTLVNSDGFDGLDSETA  421
            AIM VPAHD+RDWEFAK+++L I  V+        E +A+   G  +NSD +DGLD  +A
Sbjct  336  AIMAVPAHDERDWEFAKQFNLDIIPVLEGGNV---EEAAFTEDGLHINSDFLDGLDKASA  392

Query  422  KRKITEWLQDRGLGEKKVSYRLRDWNISRQRYWGTPIPVVYCEKCGMVPVPEDQLPVKLP  481
              K+ EWL+  G+G+ +V+YRLRDW +SRQRYWG PIP++  E     +VPE +LP+ LP
Sbjct  393  IAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLP  452

Query  482  L--DVKFTGQGN-PLETSEEFVNTTCPKCGGKARRETDTMDTFFDSSWYFLRFCDPKNDR  538
            +  D++ +G G+ PL    + ++ T    G K+RRET+TM    +SSWY+LR+ DP N  
Sbjct  453  VTKDIRPSGTGESPLANVTDWLEVTRED-GVKGRRETNTMPQWAGSSWYYLRYIDPHNTE  511

Query  539  EPFSREKVDYWMPVDVYIGGIEHAVLHLLYARFFQKFLKDLGLVRDDEPFEKLITQGM  596
                 E +  W+PVD+Y+GG EHAVLHLLYARF +K L DLG+V   EPF+KL+ QGM
Sbjct  512  KLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGM  569

1781) Celf_2373 in NC_015514


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  445 bits (1677),  Expect = 6e-126, Method: Compositional matrix adjust.
 Identities = 333/734 (46%), Positives = 472/734 (65%), Gaps = 52/734 (7%)

Query  242  LAYVSETPVNWCPGLGTVLANEEVTADGRSERGNFPVFQRSLRQWNMRITAYADRLVDDL  301
            LAY +E PVNW   LGT +ANEEV +DG SERG +PV ++++RQW ++ITAYA+RL++DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  302  ERIDWPDKVKAMQRNWIGRSTGARVRFAV-QGGSEVEVFTTRPDTLFGATFVVVAPEHPL  360
            E +DWP+ +K MQRNWIG+STGA V F V + + +  VFTTRPDTLFGAT+ V+APEH+L
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  361  LDEVPSAWPDGTHAAWTGGHRTPADAVAAYRVESAAKTAVERQADAGRKTGVFTGHLAAN  420
            +D + ++                A+AVA Y+ +++ K+ + R   A  KTGV TG  A N
Sbjct  268  VDAITTS--------------DQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAIN  313

Query  421  PVNGELLPVFTADYVLMGYGTGAIMAVPGGDERDFAFAQAFELPVVYTVDAPDGTPEGAR  480
            PVNG  +PV  ADYVL +YGTGAIMAVP+ DERD  FA+ F+L ++  +++ +   E+A 
Sbjct  314  PVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGN-VEEAAF  372

Query  481  TGDGAVINSSNDEISLDGLPVAEAKAAIIAWLERHGVGEGTVTYRLRDWLFSRQRYWGEP  540
            T DG  INS      LDGL  A A A ++ WLE +GVG+  VTYRLRDWLFSRQRYWGEP
Sbjct  373  TEDGLHINSD----FLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEP  428

Query  541  FPIVYDENdlpvalpahalpvplpdvpdyapRTFDPDDAQSSPEPPLGRNDDWVHVTLDL  600
            +PI+  E+       + A+P +   +     + + P    ++ E+PL+   DW++VT + 
Sbjct  429  IPIIHWED-----GTSTAVPESELPLVLPVTKDIRPS---GTGESPLANVTDWLEVTRE-  479

Query  601  GDGPKRYRRDTNTMPNWAGSCWYYLRYLDPTNDEVLVDPELERYWMGPGHSgdgddrvgg  660
             DG K  RR+TNTMP+WAGS WYYLRY+DP N E L D EL + W+  +           
Sbjct  480  -DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVD-----------  526

Query  661  vdlyvggvEHAVLHLLYARFWHKVLFDLGHVTSAEPFHRLFNQGYIQADVFRDERLvavp  720
              +YVGG EHAVLHLLYARFWHKVL+DLG V + EPF++LFNQG I +  +RD R   V+
Sbjct  527  --IYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVA  584

Query  721  avevveDEGSATGFSWQGRPVTREHGKMGKSLKNAVTPDEMYADYGADTLRVYEMSMGPL  780
            +  V   +GS       G  + +  +KM+KSLKN V PD++  +YGADTLRVYEM MGPL
Sbjct  585  TDKVEKRDGSFFHVE-TGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPL  643

Query  781  DQSRPWETRAVVGSQRYLQRLWRNvvdettgevtvtddAPSDETSRLLHRTIADVTADMA  840
            D S +W   ++ GS+++L+R+ R              +  S+   ++ + T+  VT ++ 
Sbjct  644  DASIAWSEEGLEGSRKFLDRVYR------LITTKEITEENSGALDKVYNETVKAVTEQVD  697

Query  841  AMRLNTAIAKLIVLNNHlttlpaapraaaealvlMTAPVAPHIAEELWLRL-GHEQSLAR  899
             M++NTAIA+L+V+ N            A ++V + AP APH++EELW  L +  +S++ 
Sbjct  698  QMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISY  757

Query  900  EPFPVADPAFLVEETVTCVLQVQGKVRGRVEVRPDVaddeltalaladaGVQRALAGRDV  959
             P P  D + LVE+ V  V+Q++GKV++++ V  D++ +EL  +ALA+  VQ  +AG+D+
Sbjct  758  VPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDI  817

Query  960  RTVIVRAPRLVNVV  973
              VI  + +LVN+V
Sbjct  818  IKVIAVPNKLVNIV  831


 Score =  134 bits (493),  Expect = 2e-32, Method: Compositional matrix adjust.
 Identities = 75/151 (50%), Positives = 104/151 (69%), Gaps = 13/151 (8%)

Query  30   IELRWQDEWQRRGTFHAANPVGGLTDGDGRLADATRPSFFVMDMFPYPSGAGLHVGHPLG  89
            IE +WQ  W    TF ++             +DA++P F+ +DMFPYPSGAGLHVGHP G
Sbjct  9    IEPKWQAFWADNHTFKTG-------------TDASKPKFYALDMFPYPSGAGLHVGHPEG  55

Query  90   YIATDVVARYRRMQGDNVLHALGFDAFGLPAEQYAVETGQHPRTTTEANIEIMQRQLRRL  149
            Y ATD+++R++R QG+NVLH++G DAFGLPAEQYA++TG++P   T  NI   +RQ+  L
Sbjct  56   YTATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINAL  115

Query  150  GLAHDPRRSFATIDPDYVRWTQWIFLQIFES  180
            G++ D  R   T DP+Y +WTQWIF +++E 
Sbjct  116  GFSYDWDREVNTTDPNYYKWTQWIFTKLYEK  146

1782) BXY_22580 in NC_021017


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  443 bits (1669),  Expect = 2e-125, Method: Compositional matrix adjust.
 Identities = 310/733 (43%), Positives = 459/733 (63%), Gaps = 74/733 (10%)

Query  204  IAYLGETMVNWCAELGTVLANDEVV-DGVSERGGFPVIQKKMRQWCLRVSAYAQRLLDGL  262
            +AY +E  VNW  ELGT +AN+EV+ DG SERGG+PV++K MRQW L+++AYA+RLL++L
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  263  DTIEWTDSLKETQRNWIGRSEGAEVQFKVKDSDLEFTIFTTRADTMFGVTFMVLAPESEL  322
            + ++W +S+K+ QRNWIG+S GA+V FKVKD+D +FT+FTTR+DT+FG T+ VLAPE  L
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  323  VAQLTTPEQKAEVDAYLDRTKKRTERERIA-DRSVTGVFSGSYAINPFTGEAVPVWISDY  381
            V  +TT++Q   V  Y  ++  +++  R    +  TGV +GSYAINP  G  +PVWI+DY
Sbjct  268  VDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAINPVNGKEMPVWIADY  327

Query  382  VLAGYGTGAIMAVPAHDSRDYAFAKHFGLEIRPLVEGCDVSEESFDAKEGIVCNSPRLDV  441
            VLA+YGTGAIMAVPAHD RD  FAK+F L+I P++EG +V E +F + +G+  N      
Sbjct  328  VLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEAAF-TEDGLHIN------  380

Query  442  TPYCDLSLNGLTIKEAIETTKKYVKEHNLGRVKVNYRLRDAIFSRQRYWGEPFPVYY-KD  500
                D+ L+GL    AI      +  + +G  +V YRLRD +FSRQRYWGEP+P+    D
Sbjct  381  ---SDF-LDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWED  436

Query  501  GMPYMIDEASLPLELPEVAKFLPTETGEPPLGHATKWAWDTVNKCVVENEKIDHVTVFPL  560
            G +  + E+ LPL LP    + P+ TGE+PL++ T W         +E  + D V     
Sbjct  437  GTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDW---------LEVTREDGVKG-RR  486

Query  561  ELNTMPGFAGSSAYYLRYMDPHNHQALVDPKIDQYWKNVDLYVGGTEHATGHLIYSRFWN  620
            E NTMP  AGSS YYLRY+DPHN + L D  + + W  VD+YVGG+EHA  HL+Y+RFW+
Sbjct  487  ETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWH  546

Query  621  KFLYDMGVSVMEEPFQKLVNQGMIQGRSNFVYRIKDTNTFVSLNLKDQYEVTPIHVDVNI  680
            K LYD+GV    EPFQKL NQGMI G S   YR     ++V+ +  ++ + + +HV+   
Sbjct  547  KVLYDLGVVPTKEPFQKLFNQGMILGTS---YR-DSRGALVATDKVEKRDGSFFHVE---  599

Query  681  VSNDILDLEAFKAWRPEYKTAEFILEDGKYVCGWAVEKMSKSMFNVVNPDMIVEKYGADT  740
             + + L+  +                           KMSKS+ NVVNPD +VE+YGADT
Sbjct  600  -TGEELEQAP--------------------------AKMSKSLKNVVNPDDVVEQYGADT  632

Query  741  LRMYEMFLGPVEQSKPWDTNGIDGVHRFIRKFWSLFYSRTDEYLVTDEPATKEELKSLHK  800
            LR+YEMF+GP++ S +W  +G++G ++F+ +   L+ ++     +T+E +   + K  + 
Sbjct  633  LRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKE----ITEENSGALD-KVYNE  687

Query  801  LIKKVTGDIEQFSYNTSISAFMICVNELFNLKCSKKEIL-----EQLVITLAPFAPHVCE  855
             +K VT +++Q  +NT+I+ +M+ VN       +K + L       +V  +APFAPH+ E
Sbjct  688  TVKAVTEQVDQMKFNTAIAQLMVFVNA-----ANKEDKLFSDYAKGFVQLIAPFAPHLGE  742

Query  856  ELWDVL-GHETSVCDAQWPAYNEEYLKEDTINYTISFNGKARFNMEFaadeasdaiqaaV  914
            ELW+ L +   S+    WP+Y+E  L E+ ++  + ++GK + ++  A D + + +Q   
Sbjct  743  ELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVA  802

Query  915  LADERSQKWIDGK  927
            LA+E+ Q  I GK
Sbjct  803  LANEKVQAEIAGK  815


 Score =  168 bits (623),  Expect = 1e-42, Method: Compositional matrix adjust.
 Identities = 92/182 (51%), Positives = 128/182 (71%), Gaps = 3/182 (1%)

Query  3    YNFREIEKKWQKRWVEEKTYQVTEDDSKQKFYVLNMFPYPSGAGLHVGHPLGYIASDIYA  62
            Y+   IE KWQ  W ++ T++   D SK KFY L+MFPYPSGAGLHVGHP GY A+DI +
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRLQGFNVLNPMGYDAYGLPAEQYAIQTGQHPAITTVNNINRYREQLDKIGFSFDWNR  122
            R+KR QG NVL+PMG DA+GLPAEQYA++TG++PA  T +NI  ++ Q++ +GFS+DW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EIRTCDPEYYHWTQWAFQKMFN-SYYCNDEQEARPIEELEKAFAIYGNEGLNAACSEDIS  181
            E+ T DP+YY WTQW F K+++ +   + E     +EEL  A+A   +E L  + SE  +
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIA--NEEVLPDGTSERGG  181

Query  182  FT  183
            + 
Sbjct  182  YP  183

1783) leuS in NC_018605


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  442 bits (1665),  Expect = 5e-125, Method: Compositional matrix adjust.
 Identities = 297/704 (43%), Positives = 444/704 (64%), Gaps = 49/704 (6%)

Query  209  LAYLKDSMVNWCEALGTVLANEEV-KDGFSERGGYPVTRKNMKQWSLRMTSYAERLLIDL  267
            LAY  +  VNW E LGT +ANEEV  DG SERGGYPV RK M+QW L++T+YAERLL DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  268  DGLDWPLSTKEMQRNWLGKSQGAEITFRVQGQKGETITVFTTRPETIFGVCFIALAPEHP  327
            + +DWP S K+MQRNW+GKS GA++TF+V+ + +  +TVFTTRP+T+FG  +  LAPEH+
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVK-DTDKDFTVFTTRPDTLFGATYAVLAPEHA  266

Query  328  WVSAMADQTGDVALIAYIEQSKNRSDRSRLAETIFLSGLFVGVCVIHPFTGAPLPIWVAD  387
             V A++      A+  Y  Q+  +SD +R   +   +G+  G   I+P  G  +P+W+AD
Sbjct  267  LVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAINPVNGKEMPVWIAD  326

Query  388  YVLPSYGKGAIMGVPAHDRRDYIFAQSFDLLTLPVIESGLLIEDGPYEAAEGKMINSDFL  447
            YVL+SYG GAIM+VPAHD RD  FA+ F+L  +PV+E+G  +E++++ + +G  INSDFL
Sbjct  327  YVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGN-VEEAAF-TEDGLHINSDFL  384

Query  448  NGLSVAEAAEKVMQKLIQNKIGQSKVNYRLQDPIFSRQRYWGEPFPIYYKEDGLPYALSQ  507
            +GL  A A  K+++ L  + +G+ +V YRL+D +FSRQRYWGEP+PI   EDG + A+++
Sbjct  385  DGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPE  444

Query  508  DHLPLVLPEVSSYTPNPSGAPPLANAFHW---STPEGY--PLDLHTMPGWAGSSWYFLRY  562
             +LPLVLP      P+ +G +PLAN  +W   +  +G     + +TMP WAGSSWY+LRY
Sbjct  445  SELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRY  504

Query  563  MDPHNRETFLSKEKEAYWKEVDFYIGGAEHATGHLLYARFWTKLLYDLGHIHISEPFPKL  622
            +DPHN E +   E    W  VD+Y+GGAEHA  HLLYARFW K+LYDLG +   EPF KL
Sbjct  505  IDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKL  564

Query  623  LHQGLIQKCTAIVYRLKDKNVLVSAGLIAQYDVVPIYIPTVFVEKNVLDLEALKNWRFEF  682
            ++QG+I   +   YR   +  LV+++ + +                              
Sbjct  565  FNQGMILGTS---YR-DSRGALVATDKVEK------------------------------  590

Query  683  RDVNFLLEEGKYVCGGKMEKMSKSKYNVVDPDSVMAQYGADALRLYLMFLGPLEQSKPWD  742
            RD +F+  E          KMSKS  NVV+PD V+ QYGAD+LR+Y MF+GPL+ S +W 
Sbjct  591  RDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWS  650

Query  743  LSGIEGLFRFLNKVWRFVHHAKASWTTTALPPNQEMVKILHQTIKKVTESIKKYSFNTAI  802
              G+EG  +FL++V R++          +   +  + K+ ++T+K VTE + +  FNTAI
Sbjct  651  EEGLEGSRKFLDRVYRLITT-----KEITEENSGALDKVYNETVKAVTEQVDQMKFNTAI  705

Query  803  SSLMIGLNRLSTFERPIQSVVEDFILLLEPFAPYIAAELWESIGKTG-SITEVAFPLWNE  861
            + LM+ +N  +  ++ +     +F+ L+ PFAP ++ ELW+++  +G SI+ V+ P  +E
Sbjct  706  AQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDE  765

Query  862  TYLAEKSFQYGIAVNGKLRTKMVFDCNASPIAIEKAVLAHEVIQ  905
            + L E+  +  + ++GK+++K+V   + S   ++   LA+E +Q
Sbjct  766  SKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQ  809


 Score =  139 bits (511),  Expect = 8e-34, Method: Compositional matrix adjust.
 Identities = 74/146 (51%), Positives = 107/146 (74%), Gaps = 3/146 (2%)

Query  4    YIFTEIEQKWQNRWREQRSVTADRSLTTNHLPKYYILNMFPYPSGSGLHVGHYMGYVASD  63
            Y  T IE KWQ  W ++++  ++   T    PK+Y L+MFPYPSG+GLHVGH  GY A+D
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTG---TDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  64   ILSRYYKHSGYHVMNPMGFDAFGLPAEQHAIQTGQHPAVTTAKNIDKYIVQLKQIALDFD  123
            ILSR+ +  G +V++PMG DAFGLPAEQ A++TG++PA  TA NI ++  Q++ +++ +D
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  124  WDKSVNTSAPEYYKWTQWIFLEMFNS  149
            WD+ VNT+ P+YYKWTQWIF  +++ 
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYEK  146

1784) leuS in NC_017861


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  442 bits (1663),  Expect = 7e-125, Method: Compositional matrix adjust.
 Identities = 299/727 (42%), Positives = 460/727 (64%), Gaps = 74/727 (10%)

Query  204  IAYLGETMVNWCPGLGTVLANDEVV-DGVSERGGYPVVQKKMKQWCLRVSAYAQRMLDGL  262
            +AY +E  VNW   LGT +AN+EV+ DG SERGGYPVV+K M+QW L+++AYA+R+L++L
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  263  EKVSWSDSMKETQRNWIGRSEGTEVVFKSFTPAGDKEIEHDITIFTTRADTMFGVTFMVL  322
            E V W++S+K+ QRNWIG+S G++V FK       K+ + D+T+FTTR+DT+FG T+ VL
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKV------KDTDKDFTVFTTRPDTLFGATYAVL  261

Query  323  APESELVPELTTDEQKAEVEEY--LAYVKKRTERDRMTDRKVTGVFTGSHGINPFTGEKL  380
            APE  LV  +TT +Q   V +Y   A +K    R  ++  K TGV TGS +INP  G  +
Sbjct  262  APEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEK-TGVWTGSYAINPVNGKEM  320

Query  381  PIYISEYVLSGYGTGAIMAVPAHDSRDYAFAKHFGLPIRPLIEGADVSEESFDAKEGIVI  440
            P+ I++YVL++YGTGAIMAVPAHD RD  FAK+F L I P++EG++V E +F + +G+ I
Sbjct  321  PVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEAAF-TEDGLHI  379

Query  441  NSPEKPVEGGFSLNGLTVKEAIEATKKYVTEQGLGKVKVNYRLRDAIFSRQRYWGEPFPV  500
            NS       +F L+GL    AI      +  +G+G+ +V YRLRD +FSRQRYWGEP+P+
Sbjct  380  NS-------DF-LDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPI  431

Query  501  YY-KEGMPYMVPAECLPLELPSIDKFEPTETGEPPLGRAKAWAWDEQNKKIVDKELIDNK  559
                +G +  VP   LPL LP    + P+ TGE+PL+    W        +   + +  +
Sbjct  432  IHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWL------EVTREDGVKGR  485

Query  560  TVFPLELNTMPGFAGSSAYYLRYMDPHNNKALVGKEANEYWQNVDLYVGGTEHATGHLIY  619
                 E NTMP  AGSS YYLRY+DPHN   L + E    W  VD+YVGG+EHA  HL+Y
Sbjct  486  R----ETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLY  541

Query  620  SRFWNKFLYDYGYSCKEEPYEKLVNQGMIQGRSNFVYRINSDDHSKAPVFVSHGLKGEYE  679
            +RFW+K LYD G     EP++KL NQGMI G S   YR     +S++++  ++ +    +
Sbjct  542  ARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS---YR-----DSRGALVATDKVEKR-D  592

Query  680  TTPIHVDVNIVHADVLDVEAFKAWRPEYENAEFILEDGKYICGWAVEKMSKSMFNVVNPD  739
             + +HV+     ++ L+  +                           KMSKS+ NVVNPD
Sbjct  593  GSFFHVET----GEELEQAP--------------------------AKMSKSLKNVVNPD  622

Query  740  DIVAQYGADTLRLYEMFLGPVEASKPWDTNGIDGCFRFLKKFWKLY-QQELNDNEPSKES  798
            D+V QYGADTLR+YEMF+GP++AS +W  +G++G  +FL +  +L   +E+ +++++  +
Sbjct  623  DVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITEENSG--A  680

Query  799  LKSV-HKLIKKISSDIEQFSYNTAISAFMICVNELGQQKCNNRGLLRSLLILIAPFAPHI  857
            L  V +  +K ++ +++Q  +NTAI+ +M+ VN   ++     +  ++++ LIAPFAPH+
Sbjct  681  LDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHL  740

Query  858  AEELWESIGENG-SVCDAQWPTWDEANLAENEVQLTISFNGKARFQMTFPTDASKEDIEK  916
            +EELW+++  +G S+    WP+ DE++L EN+V++ + ++GK + ++  + D S+E+++ 
Sbjct  741  GEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQE  800

Query  917  AAVNDER  923
             A+ +E+
Sbjct  801  VALANEK  807


 Score =  170 bits (628),  Expect = 5e-43, Method: Compositional matrix adjust.
 Identities = 88/169 (53%), Positives = 120/169 (72%), Gaps = 1/169 (0%)

Query  3    YNFTDIEKKWQKKWVENKTYKVVEDKNKQKFYVLNMFPYPSGAGLHVGHPLGYIASDIYA  62
            Y+ T IE KWQ  W +N T+K   D +K KFY L+MFPYPSGAGLHVGHP GY A+DI +
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRLKGFNVLNPMGYDAYGLPAEQYAIQTGQHPSITTDKNIARYREQLDKIGFCFDWDR  122
            R+KR +G NVL+PMG DA+GLPAEQYA++TG++P+  T  NIA ++ Q++ +GF +DWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVRTCDPQYYHWTQWAFQRMFESYYDYNEGKAKP-ISDLVRHFEEEGTL  170
            EV T DP+YY WTQW F +++E    Y+   +   + +L   + +E  L
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVL  172

1785) Bache_0699 in NC_014933


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  439 bits (1655),  Expect = 3e-124, Method: Compositional matrix adjust.
 Identities = 301/722 (42%), Positives = 449/722 (63%), Gaps = 68/722 (9%)

Query  204  IAYLGETMVNWCPQLGTVLANDEVV-DGVSERGGFPVIQKKMRQWCLRVSAYAQRLLDGL  262
            +AY +E  VNW  +LGT +AN+EV+ DG SERGG+PV++K MRQW L+++AYA+RLL++L
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  263  DTIDWTESLKETQKNWIGRSEGAEVQFKVKDSDREFTIFTTRADTMFGVTFMVLAPESEL  322
            + +DW ES+K+ Q+NWIG+S GA+V FKVKD+D++FT+FTTR+DT+FG T+ VLAPE  L
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  323  VLQLTTDTQKADVDAYLertkkrtererIA-DRSVTGVFSGSYAINPFTGEAVPIWISDY  381
            V  +TT  Q   V  Y  ++  +++  R    +  TGV +GSYAINP  G  +P+WI+DY
Sbjct  268  VDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAINPVNGKEMPVWIADY  327

Query  382  VLAGYGTGAIMAVPAHDSRDYAFAKHFGLEIRPLVEGCDVSEESFDAKEGIVCNSPRKGV  441
            VLA+YGTGAIMAVPAHD RD  FAK+F L+I P++EG +V E +F             G+
Sbjct  328  VLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEAAFTE----------DGL  377

Query  442  KPYCDLSLNGLTIKEAIAATKVYVKEHNLGRVKVNFRLRDAIFSRQRYWGEPFPVYY-KD  500
                D+ L+GL    AIA     +  + +G  +V +RLRD +FSRQRYWGEP+P+    D
Sbjct  378  HINSDF-LDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWED  436

Query  501  NMPYMIDESSLPLELPEVAKFLPTETGEPPLGHALKWAWDTANRCVVDNRKIDNITIFPL  560
              +  + ES LPL LP    + P+ TGE+PL++   W  + +    V  R+         
Sbjct  437  GTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWL-EVTREDGVKGRR---------  486

Query  561  ELNTMPGFAGSSAYYLRYMDPNNHTALVDKKVDEYWRNVDLYVGGTEHATGHLIYSRFWN  620
            E NTMP  AGSS YYLRY+DP+N   L D  +   W  VD+YVGG+EHA  HL+Y+RFW+
Sbjct  487  ETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWH  546

Query  621  KFLHDLGVSTVEEPFRKLVNQGMIQGRSNFVYRIKDTNTFVSLNLKDQYDTTPLHVDVNI  680
            K L DLGV    EPF+KL NQGMI G S   YR     ++V+ +  ++ D + +HV+   
Sbjct  547  KVLYDLGVVPTKEPFQKLFNQGMILGTS---YR-DSRGALVATDKVEKRDGSFFHVE---  599

Query  681  VSNDILDTEAFKAWRPEYKTAEFVLEDGKYVCGWAVEKMSKSMFNVVNPDMIVEKYGADT  740
             + + L+  +                           KMSKS+ NVVNPD +VE+YGADT
Sbjct  600  -TGEELEQAP--------------------------AKMSKSLKNVVNPDDVVEQYGADT  632

Query  741  LRMYEMFLGPVEQSKPWDTNGIDGVHRFIKKFWNLFYDRNDNCLVTDEPATKEELKSLHK  800
            LR+YEMF+GP++ S +W  +G++G ++F+ +   L+  ++    +T+E +   + K  + 
Sbjct  633  LRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKE----ITEENSGALD-KVYNE  687

Query  801  LIKKVTGDIETFSYNTSISAFMICVNELSGLKCSK--KEILNQFIIVLAPFAPHVCEELW  858
             +K VT +++   +NT+I+ +M+ VN  ++ K  K   +  + F+ ++APFAPH+ EELW
Sbjct  688  TVKAVTEQVDQMKFNTAIAQLMVFVN--AANKEDKLFSDYAKGFVQLIAPFAPHLGEELW  745

Query  859  EMLGNQG-SVCDSHWPACNEEYLVESSVNYTISFNGKARFNMEFPADAASDTIQTTVLAD  917
            + L   G S+    WP+ +E  LVE+ V+  + ++GK + ++  + D + + +Q   LA+
Sbjct  746  QALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALAN  805

Query  918  ER  919
            E+
Sbjct  806  EK  807


 Score =  165 bits (611),  Expect = 1e-41, Method: Compositional matrix adjust.
 Identities = 80/142 (57%), Positives = 108/142 (77%), Gaps = 0/142 (0%)

Query  3    YNFREIEKKWQKRWVENKTYQVTEDETKQKYYVLNMFPYPSGAGLHVGHPLGYIASDIYA  62
            Y+   IE KWQ  W +N T++   D +K K+Y L+MFPYPSGAGLHVGHP GY A+DI +
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRLQGFNVLNPMGYDAYGLPAEQYAIQTGQHPEVTTKANINRYREQLDKIGFSFDWNR  122
            R+KR QG NVL+PMG DA+GLPAEQYA++TG++P   T  NI  ++ Q++ +GFS+DW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EIRTCDPEYYHWTQWAFQKMFN  144
            E+ T DP+YY WTQW F K+++
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYE  145

1786) leuS in NC_009615


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  438 bits (1649),  Expect = 1e-123, Method: Compositional matrix adjust.
 Identities = 300/720 (42%), Positives = 459/720 (64%), Gaps = 63/720 (8%)

Query  204  IAYRGETMVNWCAALGTVLANDEVV-NGVSERGGYPVEQKIMRQWCLRVSAYAQRLLDGL  262
            +AY +E  VNW   LGT +AN+EV+ +G SERGGYPV +K MRQW L+++AYA+RLL++L
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  263  DTIDWTDSLKETQKNWIGRSEGAEVRFKVKDSDKEFTIFTTRADTMFGVTFMVLAPESEL  322
            + +DW +S+K+ Q+NWIG+S GA+V FKVKD+DK+FT+FTTR+DT+FG T+ VLAPE  L
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  323  VQQLTTADQKAEVDAYLDRTKKRTERERIA-DRQVTGVFSGSYAINPFTGEAVPIWISDY  381
            V+ +TT+DQ   V  Y  ++  +++  R    ++ TGV +GSYAINP  G  +P+WI+DY
Sbjct  268  VDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAINPVNGKEMPVWIADY  327

Query  382  VLAGYGTGAIMAVPAHDSRDYAFAKHFGLEIRPLVEGCDVSKESFDAKEGIVCNSPRTGV  441
            VLA+YGTGAIMAVPAHD RD  FAK+F L+I P++EG +V   +F + +G+  N      
Sbjct  328  VLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEAAF-TEDGLHIN------  380

Query  442  TPYCDLSLNGLTIKEAIAATKKYVKDHDLGRVKINYRLRDAIFSRQRYWGEPFPVYYDAD  501
                D+ L+GL    AIA     +  +++G  ++ YRLRD +FSRQRYWGEP+P+    D
Sbjct  381  ---SDF-LDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWED  436

Query  502  SMPQMlpeeclplllpeVDKFLPTETGEPPLGHAVKWAWDTVNQKVTEVSKIDNQTIFPL  561
            + +  +PE  LPL+LP    + P+ TGE+PL++   W          EV++ ++      
Sbjct  437  GTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDW---------LEVTR-EDGVKGRR  486

Query  562  ELCTMPGFAGSSAYYLRYMDPHNDKALVAKDVDEYWRNVDLYIGGTEHATGHLIYSRFWN  621
            E  TMP  AGSS YYLRY+DPHN   L   ++   W  VD+Y+GG+EHA  HL+Y+RFW+
Sbjct  487  ETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWH  546

Query  622  KFLFDLGIVCEEEPFKKLINQGMIQGRSNFVYRINGTNKFVSLNLKDQYEVTPIHVDVNI  681
            K L+DLG+V   EPF+KL+NQGMI G S   YR ++   +V+ +  ++ + + +HV+   
Sbjct  547  KVLYDLGVVPTKEPFQKLFNQGMILGTS---YR-DSRGALVATDKVEKRDGSFFHVE---  599

Query  682  VSNDLLDIEAFKNWRPEYNDAEFVLEDGKYICGWAVEKMSKSMFNVVNPDMIVEKYGADT  741
             +++L +                           A  KMSKS+ NVVNPD +VE+YGADT
Sbjct  600  TGEELEQ---------------------------APAKMSKSLKNVVNPDDVVEQYGADT  632

Query  742  LRLYEMFLGPLEQSKPWDTNGIDGVHRFLKKLWGLFFGNTDTLQVTDAEPTADELKSLHK  801
            LR+YEMF+GPL+ S +W  +G++G ++FL ++    +    T ++T+ ++ A + K  + 
Sbjct  633  LRVYEMFMGPLDASIAWSEEGLEGSRKFLDRV----YRLITTKEITEENSGALD-KVYNE  687

Query  802  LIKKVTFDIEHFSYNTSISAFMICVNELTSLKCSKRAILEPLITLLAPFAPHIAEELWHQ  861
             +K VT ++++  +NT+I+ +M+ VN               ++ L+APFAPH++EELW+ 
Sbjct  688  TVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  862  L-GHDTTICDARWPKHNEEYLKEKSVVYAISFNGKARYNLELPADISKEDAEKAALNHEN  920
            L + + +I    WP  +E  L E+ V   + ++GK + +L ++ D+S+E+ +  AL +E+
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEK  807


 Score =  177 bits (656),  Expect = 3e-45, Method: Compositional matrix adjust.
 Identities = 84/142 (60%), Positives = 110/142 (78%), Gaps = 0/142 (0%)

Query  3    YNFREIEKKWHDYWIAEKVYKVEKDTNKPKYYVLDMFPYPSGAGLHVGHPLGYIASDIYS  62
            Y+   IE KW+ +W  +  +K   D++KPK+Y LDMFPYPSGAGLHVGHP GY A+DI S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RFKRLQGFNVLHPMGYDAYGLPAEQYAIQTGQHPEITTKNNIARYREQLEKIGFCYDWSR  122
            RFKR QG NVLHPMG DA+GLPAEQYA++TG++P   T +NIA ++ Q++ +GF YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EIRTCDPEYYKWTQWAFIRMFN  144
            E+ T DP+YYKWTQW F ++++
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYE  145

1787) SACTE_1984 in NC_015953


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  437 bits (1647),  Expect = 1e-123, Method: Compositional matrix adjust.
 Identities = 358/738 (49%), Positives = 492/738 (67%), Gaps = 58/738 (7%)

Query  220  LAYASDAPVNWSPGLGTVLANEEVTADGRSERGNFPVFKAKLRQWNMRITAYAdrllddl  279
            LAY ++ PVNW   LGT +ANEEV +DG SERG +PV +  +RQW ++ITAYA+RLL+DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  280  dgldWPEAIKLQQRNWIGRSEGARVDFPVDGAG-GITVFTTRQDTLFGATYMVLAPEHDL  338
            + +DWPE+IK  QRNWIG+S GA V F V +++ ++TVFTTR DTLFGATY VLAPEH L
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  339  VERIIPAAWPEGTHPVWTGGHASPAEAVTAYRKQAAAKSDVERQAEAKDKTGVFTGAYAT  398
            V+ I  +                 AEAV+ Y++QA+ KSD+ R   AK+KTGV TG+YA 
Sbjct  268  VDAITTS---------------DQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAI  312

Query  399  NPVSGEKVPVFIADYVLMGYGTGAIMAVPAHDSRDFAFARAFELPMRCVVEPSDDRGTDP  458
            NPV+G  +PV IADYVL +YGTGAIMAVPAHD RD  FA+ F+L +  V+E ++      
Sbjct  313  NPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVE----  368

Query  459  STWEDAFSSYEAKLVNSANDEVSLDGLGVVDAKARITEWLREHGVGEGTVNFRLRDWLFS  518
               E AF+  E  L  +++    LDGL+   A A++ EWL  +GVG+  V +RLRDWLFS
Sbjct  369  ---EAAFT--EDGLHINSD---FLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  519  RQRYWGEPFPIVYDEEGIAHplpesmlplelpeveDYSPRTFDPDDADTQPETPLSRNAD  578
            RQRYWGEP+PI+  E+G + ++PES LPL LP   D  P            E+PL+  +D
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVTD  472

Query  579  WVNVTLDLGDGPKKYRRETNTMPNWAGSCWYELRYLDPNNERRLVDPEVEQYWMGPRDGQ  638
            W++VT +  DG K  RRETNTMP+WAGS WY LRY+DP+N  +L D E+ + W+      
Sbjct  473  WLEVTRE--DGVKG-RRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLP-----  524

Query  639  PAGGVDLYIGGAEHAVLHLLYARFWSKVLHDLGHISSSEPFHKLYNQGMIQAFVYRDSRG  698
                VD+Y+GGAEHAVLHLLYARFW KVL DLG +++ EPF+KL+NQGMI +  YRDSRG
Sbjct  525  ----VDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRG  580

Query  699  IAVPAAEVEERDGAYYH--QGEKVSRVLGKMGKSLKNAVTPDEICGEYGADTLRLYEMAM  756
              V++  VE RDG+++H   GE + +  +KM+KSLKN V PD++  +YGADTLR+YEM M
Sbjct  581  ALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFM  640

Query  757  GPLDVSRPWDTRAVVGQFRLLQRLWRNIvdeetgevtvvdtepdedtLRALHKAIDGVGQ  816
            GPLD S +W   ++ G  ++L+R+ R I   E  E      +      +  + ++ +V +
Sbjct  641  GPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALD------KVYNETVKAVTE  694

Query  817  DMAGMRFNTAIAKVTELNNHLTKAGGPLARSvaerlvllvaplaphvaeELWRRLGHTG-  875
            ++  M+FNTAIA++  + N   K  + L    A  +V L+AP+APH++EELW+ L  +G 
Sbjct  695  QVDQMKFNTAIAQLMVFVNAANKE-DKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGE  753

Query  876  SVVHQDFPVADPSYvvdetvtcvvqvKGKVRARLEISPSISdeelealaladenvvaalG  935
            S+     P  D S +V++ V  VVQ+KGKV+A+L ++  +S EEL+ +ALA+E+V A ++
Sbjct  754  SISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIA  813

Query  936  GAGIRKVIVRAPKLVNIV  953
            G +I KVI  + KLVNIV
Sbjct  814  GKDIIKVIAVPNKLVNIV  831


 Score =  131 bits (482),  Expect = 2e-31, Method: Compositional matrix adjust.
 Identities = 74/150 (50%), Positives = 101/150 (68%), Gaps = 10/150 (6%)

Query  22   ADIEARWQDFWDAEGTYEAPNPTGDLAGDPALAAKPKKFIMDMFPYPSGSGLHVGHPLGY  81
            + IE++WQ FW  + T+ +             A+KPK + +DMFPYPSG+GLHVGHP GY
Sbjct  7    TAIEPKWQAFWADNHTFKTGTD----------ASKPKFYALDMFPYPSGAGLHVGHPEGY  56

Query  82   IATDVYARHQRMTGHNVLHTLGFDAFGLPAEQYAVQTGTHPRISTEANMENMKAQLRRLG  141
             ATD+ +R +R  GHNVLH +G DAFGLPAEQYA++TG +P   T  N+ N K Q+  LG
Sbjct  57   TATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALG  116

Query  142  LGHDKRRSFATIDAEYYKWTQWIFLQIFNS  171
            ++ D  R   T D++YYKWTQWIF ++++ 
Sbjct  117  FSYDWDREVNTTDPNYYKWTQWIFTKLYEK  146

1788) Odosp_2649 in NC_015160


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  437 bits (1646),  Expect = 2e-123, Method: Compositional matrix adjust.
 Identities = 310/714 (44%), Positives = 459/714 (65%), Gaps = 54/714 (7%)

Query  204  IAYLADTMVNWCPQLGTVLANDEV-KEGLSVRGGFPVVQKNMRQWSLRVSAYAQRLLDGL  262
            +AY A+  VNW  +LGT +AN+EV  +G S RGG+PVV+K MRQW L+++AYA+RLL++L
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  263  NHLEWSDSLKDIQRNWIGRSQGADVIFDVKDSDIQLKIFTTRPDTIYGVSFMVLAPESDY  322
            ++++W++S+KD+QRNWIG+S GA+V F VKD+D ++ +FTTRPDT++G ++ VLAPE   
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  323  VRQLTTPDQEKAVAEYLDYVAKRTERERQSEIKTVTGVFTGSYAMNPFTNEAIPVWISEY  382
            V  +TT+DQ  AVA+Y    + +++  R    K  TGV TGSYA+NP     +PVWI++Y
Sbjct  268  VDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAINPVNGKEMPVWIADY  327

Query  383  VLAGYGTGAIMAVPAHDSRDYAFARKFNLPVIPVIDNGQPIDLSKSSYDAKEGKMINSGL  442
            VLA+YGTGAIMAVPAHD RD  FA++FNL +IPV++ G   ++  +++ + +G  INS++
Sbjct  328  VLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGG---NVEEAAF-TEDGLHINSDF  383

Query  443  IDGMEVKEAIAFIAEEVEKRGIGKSKINYRLRDAIFSRQRYWGEPFPVYY-KDSMPYMID  501
            +DG++   AIA + E +E  G+G+ ++ YRLRD +FSRQRYWGEP+P+    D+ +  + 
Sbjct  384  LDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVP  443

Query  502  EAELPLELPEIDKYLPTENGEPPLGRAKNW---TTKEGY--PIELNTMPGFAGSSAYYLR  556
            E+ELPL LP      P+  GE+PL+   +W   T  +G     E NTMP  AGSS YYLR
Sbjct  444  ESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLR  503

Query  557  YMDPHNDKALVSHEADAYWRNVDLYLGGAEHATGHLIYSRFWNMFLYDLGVVCEPEPFKK  616
            Y+DPHN   L  +E    W  VD+Y+GGAEHA  HL+Y+RFW+  LYDLGVV   EPF+K
Sbjct  504  YIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQK  563

Query  617  LINQGMIQGRSNFVYRIVGTNTYVSAGLKSQYETTEIHVDVNIVKNDILDTEAFRKWMPD  676
            L+NQGMI G S   YR                            +  ++ T+   K+   
Sbjct  564  LFNQGMILGTS---YR--------------------------DSRGALVATDKVEKRDGS  594

Query  677  YADAEFILEDGKYICGWAVEKMSKSMFNVVNPDDIIEQFGADTLRLYEMFLGPLEAHKPW  736
            +    F +E G  +   A  KMSKS+ NVVNPDD++EQ+GADTLR+YEMF+GPL+A  +W
Sbjct  595  F----FHVETGEELEQ-APAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAW  649

Query  737  DTQGIDGVYKFLRKFWRLFLNGEEFSVSDEVPTKEELKVLHKTLKKIEFDIENFSFNTSI  796
              +G++G  KFL +  RL+   E   +++E +   + KV + T+K +  ++++  FNT+I
Sbjct  650  SEEGLEGSRKFLDRVYRLITTKE---ITEENSGALD-KVYNETVKAVTEQVDQMKFNTAI  705

Query  797  PAFMICTNELAALKCNK--RAILEPLVVAIAPYAPHIAEELWH-LLGHAESVTGATFPQW  853
            + +M+  N  AA K +K        +V  IAP+APH++EELW+ L + +ES++    P  
Sbjct  706  AQLMVFVN--AANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSY  763

Query  854  EEKYLVEDSFEYPVSFNGKVRFKLNMPLTATQAEIEAAVKASPEAGKWLEGKEI  907
            +E  LVE+  E  V ++GKV+ KL ++   ++ E++    A+      + GK+I
Sbjct  764  DESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDI  817


 Score =  179 bits (665),  Expect = 5e-46, Method: Compositional matrix adjust.
 Identities = 89/142 (63%), Positives = 117/142 (83%), Gaps = 0/142 (0%)

Query  3    YNFKEVEKKWQSYWKENQTYKVDVDPSKPKFYVLDMFPYPSGAGLHVGHPLGYIASDIYS  62
            Y+   +E KWQ++W +N+T+K + D+SKPKFY LDMFPYPSGAGLHVGHP GY A+DI S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRLKGFNVLHPMGFDAYGLPAEQYAIQTGQHPAITTEKNIARYREQLDKIGFSFDWDR  122
            R+KR +G NVLHPMG DA+GLPAEQYA++TG++PA  T  NIA ++ Q++ +GFS+DWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVRTCDPKYYKWTQWAFIQMFN  144
            EV T DP+YYKWTQW F ++++
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYE  145

1789) leuS in NC_004663


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  436 bits (1643),  Expect = 3e-123, Method: Compositional matrix adjust.
 Identities = 290/700 (42%), Positives = 440/700 (63%), Gaps = 64/700 (9%)

Query  204  IAYLGETMVNWCQALGTVLANDEVI-DGVSERGGFPVVQKKMRQWCLRVSAYAQRLLDGL  262
            +AY +E  VNW + LGT +AN+EV+ DG SERGG+PVV+K MRQW L+++AYA+RLL++L
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  263  DTIDWTESLKETQKNWIGRSEGAEVQFKVKDSDLEFTIFTTRADTMFGVTFMVLAPESDL  322
            + +DW ES+K+ Q+NWIG+S GA+V FKVKD+D +FT+FTTR+DT+FG T+ VLAPE  L
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  323  VAQLTTPAQKAEVDAYLDRTKKRTERERIA-DRSVTGVFSGSYAINPFTGEAVPIWISDY  381
            V  +TT+ Q   V  Y  ++  +++  R    +  TGV +GSYAINP  G  +P+WI+DY
Sbjct  268  VDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAINPVNGKEMPVWIADY  327

Query  382  VLAGYGTGAIMAVPAHDSRDYAFAKHFGLEIRPLVEGCDVSEESFDAKEGIVCNSPRPDV  441
            VLA+YGTGAIMAVPAHD RD  FAK+F L+I P++EG +V E +F + +G+  N      
Sbjct  328  VLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEAAF-TEDGLHIN------  380

Query  442  TPYCDLSLNGLTIKEAIEKTKQYVKEHNLGRVKVNYRLRDAIFSRQRYWGEPFPVYY-KD  500
                D+ L+GL    AI K  + +  + +G  +V YRLRD +FSRQRYWGEP+P+    D
Sbjct  381  ---SDF-LDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWED  436

Query  501  GMPYMIDEDCLPLELPEVDKFLPTETGEPPLGHAKEWAWDTVNKCTVENEKIDNVTIFPL  560
            G +  + E  LPL LP    + P+ TGE+PL++  +W  +      V   +         
Sbjct  437  GTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWL-EVTREDGVKGRR---------  486

Query  561  ELNTMPGFAGSSAYYLRYMDPHNNKALVDPKVDEYWKNVDLYVGGTEHATGHLIYSRFWN  620
            E NTMP  AGSS YYLRY+DPHN   L D  +   W  VD+YVGG+EHA  HL+Y+RFW+
Sbjct  487  ETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWH  546

Query  621  KFLHDVGASVVEEPFQKLVNQGMIQGRSNFVYRIKDTHTFVSLNLKDQYEVTPLHVDVNI  680
            K L D+G     EPFQKL NQGMI G S   YR     ++V+ +  ++ + + +HV+   
Sbjct  547  KVLYDLGVVPTKEPFQKLFNQGMILGTS---YR-DSRGALVATDKVEKRDGSFFHVE---  599

Query  681  VSNDILDLEAFKAWRPEYAEAEFILEDGKYICGWAVEKMSKSMFNVVNPDMIVDKYGADT  740
             + + L+  +                           KMSKS+ NVVNPD +V++YGADT
Sbjct  600  -TGEELEQAP--------------------------AKMSKSLKNVVNPDDVVEQYGADT  632

Query  741  LRMYEMFLGPVEQSKPWDTNGIDGVHRFIRKFWSLFYSRTDEYLVKDEPATKEELKSLHK  800
            LR+YEMF+GP++ S +W  +G++G ++F+ +   L+ ++    +  +++++ +  K  + 
Sbjct  633  LRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKE---ITEENSGALD--KVYNE  687

Query  801  LIKKVTGDIEQFSYNTSVSAFMICVNELSNLKCNKKEILEQLVITLAPFAPHVCEELWDT  860
             +K VT +++Q  +NT+++ +M+ VN  ++      +    +V  +APFAPH+ EELW++
Sbjct  688  TVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQA  747

Query  861  L-GHETSVCDAAWPAYNEEYLKEDTINYTISFNGKARFNM  899
            L +   S+   +WP+Y+E  L E+ ++  + ++GK + ++
Sbjct  748  LTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKL  787


 Score =  165 bits (609),  Expect = 1e-41, Method: Compositional matrix adjust.
 Identities = 91/194 (47%), Positives = 130/194 (68%), Gaps = 8/194 (4%)

Query  3    YNFREIEKKWQQRWVEEKTYQVTEDESKQKFYVLNMFPYPSGAGLHVGHPLGYIASDIYA  62
            Y+   IE KWQ  W ++ T++   D SK KFY L+MFPYPSGAGLHVGHP GY A+DI +
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRLRGFNVLNPMGYDAYGLPAEQYAIQTGQHPAITTKANIDRYREQLDKIGFSFDWSR  122
            R+KR +G NVL+PMG DA+GLPAEQYA++TG++PA  T  NI  ++ Q++ +GFS+DW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EIRTCEPEYYHWTQWAFQKMFN-SYYCNDEQQARPIQELIDAFAIYGNEGLNAACSEELS  181
            E+ T +P+YY WTQW F K+++ +   + E     ++EL  A+A   +E L  + SE  +
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIA--NEEVLPDGTSERGG  181

Query  182  FTA-----KEWKAK  190
            +       ++W  K
Sbjct  182  YPVVRKPMRQWMLK  195

1790) leuS in NC_009613


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  436 bits (1643),  Expect = 3e-123, Method: Compositional matrix adjust.
 Identities = 306/748 (41%), Positives = 460/748 (62%), Gaps = 87/748 (11%)

Query  205  LTYLAETEVNWCPGLGTVLANDEII-NGVSERGGHPVIRKKMTQWSMRISAYAERLLQGL  263
            L+Y AE  VNW   LGT +AN+E++ +G SERGG PV+RK M QW ++I+AYAERLL++L
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  264  NDIDWSESIKESQRNWIGKSVGAMVSFKVKNQKSQVTSEATLSDLRPSTLDYIEVFTTRP  323
            +++DW+ESIK+ QRNWIGKS GA V+FKVK+   + T                 VFTTRP
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFT-----------------VFTTRP  250

Query  324  DTIFGVTFMTLAPEHPLVQEITTPEQKAAIEAYIEKTAKRSERERMADVKTISGVFTGAY  383
            DT+FG T+  LAPEH+LV+ ITT++Q  A+  Y  +++ +S+  R    K  +GV TG+Y
Sbjct  251  DTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSY  310

Query  384  AEHPFTKEQIPVWIGDYVLAGYGTGAVMAVPCGDERDYAFANFFKGQNGMPEIKNIFDNV  443
            A +P    ++PVWI+DYVLA+YGTGA+MAVP  DERD  FA+ F+      +I  +++  
Sbjct  311  AINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFN-----LDIIPVLEGG  365

Query  444  DIATEAYGSKDNVIIANSDFLNGLNYKQATKKAIAELETLNQGKGKTNYRLRDAVFSRQR  503
            ++   A+   ++ +  NSDFL+GL+   A  K +  LE+   G+ +  YRLRD +FSRQR
Sbjct  366  NVEEAAFT--EDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQR  423

Query  504  YWGEPFPV-YYVNGLPQMIDAKHLPIALPEVEKYLPTEDGLPPLGNSAKWAWNTITNEVD  562
            YWGEP+P+    +G +  +   +LP+ LP      P+  G +PL+N + W       EV 
Sbjct  424  YWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWL------EVT  477

Query  563  FNENINNTTIYPLELNTMPGWAGSSWYWMRYMDPHNDNEFASPEAIKYWESVDLYIGGSE  622
             ++ ++       E NTMP WAGSSWY +RY+DPHN + +A  E +K W +VD+Y+GG+E
Sbjct  478  REDGVKGRR----ETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAE  533

Query  623  HATGHLLYARFWNKFLKDKGYAPTEEPFKKLINQGMILGNSAFVYRSEDSKKLYSKGLIS  682
            HA  HLLYARFW+K L D G  PT EPF+KL+NQGMILG S   YR +    L + + + 
Sbjct  534  HAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS---YR-DSRGALVATDKVE  589

Query  683  DKTTQAIHVDLAIINETTNELDIEAFKKHPLYSDYANAEFILENGKYIVGREVEKMSKSK  742
             +    +HV      ET +EL+                            +   KMSKS 
Sbjct  590  KRDGSFFHV------ETGEELE----------------------------QAPAKMSKSL  615

Query  743  YNVVNPDDICNEYGADTLRLYEMFLGPLEQSKPWNTAGITGVFGFLKKLWRLYFDDNGLI  802
             NVVNPDD+ ++YGADTLR+YEMF+GPL+ S +W+  G+ G   FL ++ RL        
Sbjct  616  KNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRL--------  667

Query  803  VTNNEPSKESLKSLHK----TIKKVTEDIENFSFNTSVSQFMICVNELGTQNCHERAILE  858
            +T +E + E+  +L+K    T+K VTE++++  FNT+++Q+M+ VN    ++        
Sbjct  668  ITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAK  727

Query  859  PLAIILSPYAPHIAEELWSQL-GNSESISTVAFPICHEKYLVESDKEYPVSFNGKMKFTI  917
             +  +++P+APH++EELW  L +++ESIS V+ P  +E  LVE+D E  V ++GK+K  +
Sbjct  728  GFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKL  787

Query  918  NLPLDLTPAQIEEIIMKDERTIKQLDGN  945
             ++ DL+  +++E+ + +E+   ++ G+
Sbjct  788  VVAKDLSREELQEVALANEKVQAEIAGK  815


 Score =  170 bits (630),  Expect = 3e-43, Method: Compositional matrix adjust.
 Identities = 84/142 (60%), Positives = 115/142 (81%), Gaps = 0/142 (0%)

Query  3    YNPNEIDAKWQKNWANNQTFAASNTSIKPKYYILDMFPYPSGAGLHVGHPLGYIASDIVA  62
            Y+   I++KWQ  WA+N+TF ++  + KPK+Y LDMFPYPSGAGLHVGHP GY A+DI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RFKRHKGFNVLHPQGYDSFGLPAEQYAIQTGQHPDKTTKENIARYREQLDKIGFSFDWSR  122
            RFKR +G NVLHP G D+FGLPAEQYA++TG++P   T ENIA ++ Q++ +GFS+DW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EIRTSNANYYKHTQWIFIQLFN  144
            E+ T+++NYYK TQWIF +L++
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYE  145

1791) C427_3472 in NC_020514


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  433 bits (1631),  Expect = 2e-122, Method: Compositional matrix adjust.
 Identities = 271/591 (46%), Positives = 406/591 (69%), Gaps = 22/591 (3%)

Query  6    YQPQEIEKEVQAYWETQQTFKATEDADKEKFYCLSMFPYPSGR-LHMGHVRNYTIGDVIS  64
            Y+   IE   QA+W  ++TFK+  DA K KFY L MFPYPSG  LH+GH   YT  D++S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  65   RYQRMLGKNVLQPMGWDAFGlpaenaalnnntapanWTYSNIEYMKTQLKTLGFGYDWDR  124
            R++R  G NVL+PMGWDAFGLPAE+ A++    PA+ T  NI   K Q+++LGF+YDWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  125  EIATCKKDYYRWEQWFFTRLFEKGLVYKKNATVNWDPVDHTVLANEQVI-DGRGWRSGAL  183
            E+ T   +YY+W QW+FT+L+EKGL Y  +  VNW     T +ANE+V+ DG + R+G  
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYP  183

Query  184  VEQKEIPQWFLKITDYAEELVNDLEQLEEWPEQVRAMQKNWIGRSEGVEITFALEQTVAQ  243
            V +K + QW LKIT YAE L++DLE++ +WPE ++ MQ+NWIG+S G ++TF + +T   
Sbjct  184  VVRKPMRQWMLKITAYAERLLEDLEEV-DWPESIKDMQRNWIGKSTGANVTFKVKDTD--  240

Query  244  LNNFDVYTTRPDTLLGVTYVAVAAQHPI--SLEAAKNNIVLAAFI-EECKTTKVAEADMA  300
             ++F V+TTRPDTL+G TY  +A++H++  ++ ++ +   +A +  +    + +A +D+A
Sbjct  241  -KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA  299

Query  301  TMEKKGCATGYFAIHPLTGDKVPVWVANFVLMGYGSGAVMAVPGHDQRDWEFATKYELEI  360
              EK G  TG +AI+P+ G  +PVW+A++VL +YG+GA+MAVP+HD+RDWEFA +++L+I
Sbjct  300  -KEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDI  358

Query  361  KQVVQGDAQNNIECDLTQGAFTEKGLLVNSGEFDGLTSAEAFEKIAQALSEQGKGKKKIN  420
              V++G+       ++ ++AFTE GL +NS+ +DGL  A A+ K+ + L  +G G+ ++ 
Sbjct  359  IPVLEGG-------NVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVT  411

Query  421  YRLRDWGVSRQRYWGTPIPMLNLENGESVPVPSNQLPVELP--EDVQMNGV-ISPIKADP  477
            YRLRDW  SRQRYWG PIP+++ E+G S +VP ++LP+ LP   D++ +G   SP+    
Sbjct  412  YRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVT  471

Query  478  EW-AKTEFNGQPALRETDTFDTFMESSWYYARYCSAQNDQAMLDPAQANYWLPVDQYVGG  536
            +W   T  +G  + RET+T      SSWYY RY  ++N + + D    + WLPVD YVGG
Sbjct  472  DWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGG  531

Query  537  IEHAILHLLYSRFFHKLLRDEGLVQSDEPYKRLLCQGMVLADSFYREDAAG  587
             EHA+LHLLY+RF HK+L D G+V + EP+++L+ QGM+L+ S YR+  ++
Sbjct  532  AEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS-YRDSRGA  581

1792) leuS in NC_017080


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  429 bits (1617),  Expect = 3e-121, Method: Compositional matrix adjust.
 Identities = 338/763 (45%), Positives = 475/763 (63%), Gaps = 75/763 (9%)

Query  217  LDSRRLAFLAEVEVNWCPKLGTVLANEEVKADGRSERGNHPVVKRPLKQWMLRITEYAER  276
            L  + LA+ AEV VNW   LGT +ANEEV +DG SERG  PVV++P++QWML+IT YAER
Sbjct  143  LYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAER  202

Query  277  LEDGLDGLDWPEPVKQLQRNWIGRSTGAEvdfdvagpagddadagrvEKITVFTTRPDTL  336
            L ++L+ +DWPE++K++QRNWIG+STGA+               +    +TVFTTRPDTL
Sbjct  203  LLEDLEEVDWPESIKDMQRNWIGKSTGAN---------VTFKVKDTDKDFTVFTTRPDTL  253

Query  337  FGATYMVLAPEHPLVEDLTTPEQKEAVDAYVARCAAMSDEERQAAAGSLPGKKTKSGVPT  396
            FGATY VLAPEH+LV+ +TT++Q EAV  Y  + +  SD  R   A      K K+GV T
Sbjct  254  FGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLA------KEKTGVWT  307

Query  397  GGFAVNPVNGEPLPVWIADYVLMGYGTGAIMAVPAHDTRDHAFAVQHDLPIVQVIDGPGG  456
            G++A+NPVNG  +PVWIADYVL +YGTGAIMAVPAHD RD  FA Q +L I+ V++G   
Sbjct  308  GSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNV  367

Query  457  TDTDLEAWTGTGPLMNSANAELDLNGLDQATATEDIVGYLEQEGRGREKTQVRLRDWLFS  516
             ++ +   T  G  +NS      L+GLD+A+A   +V  LE EG G E+   RLRDWLFS
Sbjct  368  EEAAF---TEDGLHINSDF----LDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFS  420

Query  517  RQRYWGEPFPILHGPGGEIRPVDEADLPVELPEMEDFRPAPPEEQDGTAPPEPPLGRAPV  576
            RQRYWGEP+PI+H  +G   +V E++LP+ LP   D+RP        ++  E+PL+    
Sbjct  421  RQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRP--------SGTGESPLANVT-  471

Query  577  AWRKVIL-DGVEYSRELNTMPNWAGSCWYYLRYLSPGDDDRLVDPGAEAYWMGADDPERS  635
             W  V   DGV   RE NTMP+WAGS WYYLRY+ P + ++L D      W+        
Sbjct  472  DWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWL--------  523

Query  636  GVDLYVGGVEHAVLHLLYARFWHQVLFDLGHVSSPEPFRRYFPQGYIQAFYYEDAEGVRV  695
             VD+YVGG EHAVLHLLYARFWH+VL+DLG V++ EPF++ F QG I +  Y D+ G  V
Sbjct  524  PVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALV  583

Query  696  EASAVVDAKSGKPAAEVQDRDEAELELRCEGRPVTRHFGKMGKSLKNAVSPDAVIQTYGC  755
                        ++  V+ RD + +++   G  + +  +KM+KSLKN V+PD V++ YG 
Sbjct  584  ------------ATDKVEKRDGSFFHVET-GEELEQAPAKMSKSLKNVVNPDDVVEQYGA  630

Query  756  DTLRLYEMSMGPLEQSKVWNTADIVGVHRFLNRVWRNLVgddtpgegsseggstpggAPL  815
            DTLR+YEM MGPL+ S  W+  ++ G ++FL+RV R +   +                  
Sbjct  631  DTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEIT----------------  674

Query  816  VSEDEPEAELRKLMARTIDRVSRAMDQMHFNVAVSALIEFNNALVARETVPHRaavtlvt  875
               +E  + L K+   T+  V+  +DQM FN A++ L+ F NA    + +    A  +V 
Sbjct  675  ---EENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQ  731

Query  876  llaplaphlaeelWERLGLHEGRYASVadapwpdadpddLVEDTLELPVQVNGKLRARVT  935
            L+AP+APHL+EELW+ L        S++  PWP  D   LVE+ +E+ VQ++GK++A++ 
Sbjct  732  LIAPFAPHLGEELWQALTASG---ESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLV  788

Query  936  VPadanrdaveaaaradgnvavHLDGLDVKKVVIVPGKLVNFV  978
            V+ D +R+ ++  A A+ +V  ++ G D+ KV+ VP KLVN+V
Sbjct  789  VAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIV  831


 Score =  142 bits (521),  Expect = 1e-34, Method: Compositional matrix adjust.
 Identities = 79/146 (55%), Positives = 101/146 (70%), Gaps = 6/146 (4%)

Query  3    YPFAEIESRWQRRWEANRTFKTPNPGDAGFNADAPPFYVLDMFPYPSGVGLHVGHPLGYI  62
            Y  + IE++WQ  W  N+TFKT      G +A  P FY LDMFPYPSG GLHVGHP GY 
Sbjct  4    YDHTAIEPKWQAFWADNHTFKT------GTDASKPKFYALDMFPYPSGAGLHVGHPEGYT  57

Query  63   ATDIVARHKRMKGFNVLHPMGFDAFGLPAEQFAIEHNVHPRVTTEKNIETMVAQLKSLGL  122
            ATDI++R KR +G NVLHPMG DAFGLPAEQ+A++   +P   T  NI     Q+++LG+
Sbjct  58   ATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGF  117

Query  123  GYDWSRRLATTDPGFVRWTQWAFLQM  148
            +YDW R + TTDP + +WTQW F ++
Sbjct  118  SYDWDREVNTTDPNYYKWTQWIFTKL  143

1793) Niako_6939 in NC_016609


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  428 bits (1610),  Expect = 1e-120, Method: Compositional matrix adjust.
 Identities = 314/725 (44%), Positives = 472/725 (66%), Gaps = 52/725 (7%)

Query  211  LAYCGYGEVNWCEALGTVLANDEVV-NGVSERGGYPVVKKKLRQWYLRITEYADRLLEGL  269
            LAY +   VNW E LGT +AN+EV+ +G SERGGYPVV+K +RQW L+IT YA+RLLE+L
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  270  DRIEFSESMKEMQTNWIGKSYGAEITFDIQGNSDKLTVYTTRPDTIFGVDFMVIAPEHAL  329
            + ++ +ES+K+MQ NWIGKS GA++TF +++    +TV+TTRPDT+FG  + V+APEHAL
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  330  IKNITsseqqqaveeyveyvqsRSERERMA-EKKISGVFTGAYAINPFNGSSIPIWISEY  388
            +  IT+S+Q +AV +Y      +S+  R    K  +GV TG+YAINP NG  +P+WI++Y
Sbjct  268  VDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAINPVNGKEMPVWIADY  327

Query  389  VLAGYGTGAIMAVPCGDERDHKFANHFNIPITNIIGSAYDGKEANATKDAKLENSDFLNG  448
            VLA+YGTGAIMAVP  DERD  FA++FN+ I  ++ ++ +  EA  T D+   NSDFL+G
Sbjct  328  VLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGG-NVEEAAFTEDGLHINSDFLDG  386

Query  449  MVMRNAMEVVIQKIEEMGIGVRKVNFRMRDAAFSRQRYWGEPFP-IKWKHGIAYplpene  507
            +   +A+  +++ +E  G+G  +V +R+RD  FSRQRYWGEP+P I W +G + ++PE+E
Sbjct  387  LDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESE  446

Query  508  lplelpHVESYKPGPEGEGPLANIPAW--TSRD------LETNTMPGYAGSSWYFLRYMD  559
            LPL LP     +P+  GE+PLAN+  W   +R+       ETNTMP  AGSSWY+LRY+D
Sbjct  447  LPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYID  506

Query  560  PHNEAEFCSRKASDYWGQVDLYIGGTEHAVGHLLYSRMWTKALYDLGFIGHDEPYKKLVN  619
            PHN   +        W  VD+Y+GG+EHAV HLLY+R W K LYDLG +   EP++KL N
Sbjct  507  PHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFN  566

Query  620  QGMIQGSSRFVYRIHGTNKYVSLGLKDQYQTDAIHVDVNIVDGVELDVEAFKKWRSDYES  679
            QGMI G+S   YR ++    V+ +  ++ +   +HV+     G EL+  +          
Sbjct  567  QGMILGTS---YR-DSRGALVATDKVEKRDGSFFHVET----GEELEQAP----------  608

Query  680  AEFILEDGKYICGTEVEKMSKRLYNTVNPDDVVNKYGADTFRMYEMFLGPVEQSKPWETK  739
                             KMSK L N VNPDDVV++YGADT+R+YEMF+GP++ S +W   
Sbjct  609  ----------------AKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEE  652

Query  740  GIEGTHRFLKKLWRLFYDETKGKVWTEEKATPAELKVLHKTIKKIEEDTERFSFNTGVSA  799
            G+EG+++FL ++ RL+   TK    TEE++ + + KV + T+K + E+ ++  FNT+++ 
Sbjct  653  GLEGSRKFLDRVYRLI--TTKEI--TEENSGALD-KVYNETVKAVTEQVDQMKFNTAIAQ  707

Query  800  FMVCVNELIDLKCnkkeilenlliilTPYAPHVSEELWHLLGNSNSILD-AAFPKVNESY  858
            +MV VN          +    ++ +++P+APH++EELW+ L  S   +   + P  +ES 
Sbjct  708  LMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESK  767

Query  859  LVESSKEYPISVNGKLRTTITISLDATQEEVEKIALGNEIVQKWMEGKPHKKIIYVKGKM  918
            LVE+  E  + ++GK+++ + ++ D ++EE++ +AL+NE VQ  + GK   K+I V  K+
Sbjct  768  LVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKL  827

Query  919  VNVVV  923
            VN+V+
Sbjct  828  VNIVI  832


 Score =  177 bits (655),  Expect = 4e-45, Method: Compositional matrix adjust.
 Identities = 91/142 (65%), Positives = 114/142 (81%), Gaps = 0/142 (0%)

Query  3    YNFRDIEKKWQAQWKASGAYKVSNDSPKPKFYVLDMFPYPSGVGLHVGHPLGYIASDIYS  62
            Y+   IE KWQA W  + ++K + D++KPKFY LDMFPYPSG GLHVGHP GY A+DI S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RFKRLKGFNVLHPMGYDAFGLPAEQYAIDHGVHPAVSTDQNIGNFRRQLDNIGFCFDWDR  122
            RFKR +G NVLHPMG DAFGLPAEQYA+D G +PA  T +NI+NF+RQ++ +GF +DWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EFRTSDPQYYKWTQWIFLQLFH  144
            E  T+DP+YYKWTQWIF +L++
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYE  145

1794) leuS in NC_015571


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  427 bits (1609),  Expect = 1e-120, Method: Compositional matrix adjust.
 Identities = 300/704 (43%), Positives = 443/704 (63%), Gaps = 55/704 (7%)

Query  204  LAYLGDTMVNWCPALGTVLANDEV-KDGVSERGGHPVEQKKMRQWCLRVSAYAERLLHDL  262
            LAY ++  VNW   LGT +AN+EV  DG SERGG PV +K MRQW L+++AYAERLL+DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  263  ETLDWTESLKETQRNWIGRSEGAEMEFRLAGKDCTFTIFTTRADTIFGVTFMVLAPesel  322
            E +DW ES+K+ QRNWIG+S GA++ F++ + D  FT+FTTR+DT+FG T+ VLAPE  L
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  323  veevtteeQRAAVEAYLtetkrrtererIS-DKRVSGVFSGSYAINPLTGKEIPIWISDY  381
            V+ +TT +Q  AV  Y  ++  +++  R    K  +GV +GSYAINP+ GKE+P+WI+DY
Sbjct  268  VDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAINPVNGKEMPVWIADY  327

Query  382  VLAGYGTGAIMAVPAHDTRDFAFARHFDLPIVQVVVPEGETATDPATWEDAKDSKSGIMV  441
            VLA+YGTGAIMAVPAHD RD  FA++F+L I+ V+  EG    ++A       +  G+ +
Sbjct  328  VLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL--EGGNVEEAAF------TEDGLHI  379

Query  442  NSDFLNGLSVEDAIAQTKEYIREKHLGCVKVNYRLRDAIFSRQRYWGEPFPIYY-KEGMP  500
            NSDFL+GL    AIA+  E +    +G  +V YRLRD +FSRQRYWGEP+PI    +G +
Sbjct  380  NSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTS  439

Query  501  HALDEDRLPLRLPEVDKFLPTESGEPPLGRATGW---HTAEGY--PYELSTMPGFAGSSA  555
             A+ E  LPL LP    + P+ +GE+PL+  T+W      +G     E +TMP  AGSS 
Sbjct  440  TAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVKGRRETNTMPQWAGSSW  499

Query  556  YYLRYMDPQNDTALVSRSANEYWRHVDLYIGGTEHATGHLIYSRFWNKFLFDLGIVCEAE  615
            YYLRY+DP+N   L        W  VD+Y+GG+EHA  HL+Y+RFW+K L+DLG+V   E
Sbjct  500  YYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKE  559

Query  616  PFRKLVNQGMIQGRSNFVYRIKNTNTFVSYGLREQYEVTPLHVDVNIVSNDQLDIDRFRA  675
            PF+KL NQGMI G S   YR  +  ++V+ +  E+ + + +HV+    + ++L+      
Sbjct  560  PFQKLFNQGMILGTS---YR-DSRGALVATDKVEKRDGSFFHVE----TGEELEQAP---  608

Query  676  WRPEYTSAEFILEDGKYICGWAIEKMSKSMFNVVNPDDIIARYGADTLRLYEMFLGPLEQ  735
                                    KMSKS+ NVVNPDD++ +YGADTLR+YEMF+GPL+ 
Sbjct  609  -----------------------AKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  736  SKPWDTNGIDGVHRFLKKFWALYYNADGIRVTDTAPTKEELKSLHKLIKKVGQDIESFSF  795
            S +W  +G++G ++FL +   +Y       +T+  +   + K  +  +K V ++++   F
Sbjct  646  SIAWSEEGLEGSRKFLDR---VYRLITTKEITEENSGALD-KVYNETVKAVTEQVDQMKF  701

Query  796  NTSIPAFMICVNELTAAKTTSRAILCPLLTVLSPFAPHITEWLWQELGVEGSIVT-ATWP  854
            NT+I+ +M+ VN               ++ +++PFAPH+ E LWQ L   G  ++   WP
Sbjct  702  NTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWP  761

Query  855  EYNEEYLVESCVRYPVSFNGKVRFNIELPADMSKEDVEQAALTA  898
             Y+E  LVE+ V   V ++GKV+ ++ ++ D+S+E++++ AL+ 
Sbjct  762  SYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALAN  805


 Score =  163 bits (603),  Expect = 5e-41, Method: Compositional matrix adjust.
 Identities = 84/142 (60%), Positives = 110/142 (78%), Gaps = 0/142 (0%)

Query  3    YNFQEIEKRVQGQWRKDKVYRVAEDTSKKPFYVLDMFPYPSGAGLHVGHPLGYIASDIFS  62
            Y+   IE + Q+ W  +  ++ + D+SK  FY LDMFPYPSGAGLHVGHP GY A+DI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRLRGFNVLHPMGYDAFGLPAEQYAIQTGQHPEKTTEENTARYREQLDKIGFSYDWER  122
            R+KR +G NVLHPMG DAFGLPAEQYA++TG++P   T EN A ++ Q++ +GFSYDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EIRTCDPNYYKWTQWAFLKMFD  144
            E+ T DPNYYKWTQW F K+++
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYE  145

1795) Ftrac_1194 in NC_014759


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  425 bits (1599),  Expect = 8e-120, Method: Compositional matrix adjust.
 Identities = 291/702 (42%), Positives = 434/702 (62%), Gaps = 59/702 (8%)

Query  206  IAYLSEAVVNWCPALGTVLSNDEV-KDGYSERGGHPVERKKMMQWSMRISAFADRLLRGL  264
            +AY +E  VNW   LGT ++N+EV  DG SERGG PV RK M QW ++I+A+A+RLL +L
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  265  EDLDWPEPVKEMQRNWIGKSVGAQLAFQLAENEEKIEVFTTRIDTIYGVTFMVLAPEHEL  324
            E++DWPE++K+MQRNWIGKS GA+++F++ + +  + VFTTR DT++G T+ VLAPEH L
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  325  VEKITTDAQRQAVEEYVNVAKNRSERERMTEVKRVSGVFTGAYAVHPFTEEKIPVWIGDY  384
            V+ ITT  Q +AV +Y   A  +S+  R    K  +GV TG+YA++P     +PVWI+DY
Sbjct  268  VDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAINPVNGKEMPVWIADY  327

Query  385  VLAGYGTGAVMAVPSDDDRDKAFAEHFELPIVEVVD----------EHEKIINSDFLTGL  434
            VLA+YGTGA+MAVP++D+RD  FA +F+L I+ V++          E+   INSDFL GL
Sbjct  328  VLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEAAFTEDGLHINSDFLDGL  387

Query  435  SIKDAQMKAIDFMKDKGIGYAKINYRMRDAIFSRQRYWGEPVPVYFKNEIPYlleeeqlp  494
                A  K ++ +   G+G  ++ YR+RD +FSRQRYWGEP+P+   ++       E   
Sbjct  388  DKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESEL  447

Query  495  lelpeVDKYL-PTEDGEPPLARAKNW---KTEDGYE--LEKSTMPGWAGSSWYMFRYMDA  548
              +  V K + P+  GE+PLA   +W     EDG     E +TMP WAGSSWY +RY+D+
Sbjct  448  PLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDP  507

Query  549  QNKDVFVDEEKQQYWQNVDLYIGGSEHATGHLLYSRFWTKFLYDLGYISVDEPFQKMINQ  608
            +N + + DEE  + W  VD+Y+GG+EHA  HLLY+RFW K LYDLG ++  EPFQK++NQ
Sbjct  508  HNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQ  567

Query  609  GMIQGRSNFVYRIEGENKFVSHGLKDQYKTQSLHVDVNIVHNDVLDLEVFKKWRPEHADA  668
            GMI G S   YR ++   +V+ +  ++     +HV+         +LE            
Sbjct  568  GMILGTS---YR-DSRGALVATDKVEKRDGSFFHVETGE------ELE------------  605

Query  669  EFILEDGKYICGAEVEKMSKSKYNVVNPDDVIEKYGADTLRLYEMFLGPLEQFKPWNTNG  728
                            KMSKS  NVVNPDDV+E+YGADTLR+YEMF+GPL+   +W+ +G
Sbjct  606  ------------QAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEG  653

Query  729  IDGTAKFLKKLWRLFHDTNGNFKVEEGEADKKAL-KALHQAIQKAEYDIENFSFNTSVST  787
            ++G+ KFL ++ RL+         E  E +  AL K  +++++    ++++  FNT+++ 
Sbjct  654  LEGSRKFLDRVYRLITTK------EITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQ  707

Query  788  FMICVNTLTELKCNNKAVLSDLVRIIAPYAPHICEELWSLLGNEG-SISEAGWPTFNPDF  846
            +M+ VN+             ++V++IAP+APH+ EELW  L   G SIS   WP+++   
Sbjct  708  LMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESK  767

Query  847  VKEDEHTYPVSVNGKHRDNMTFALDAPKEEIEKAVLENPKVQ  888
            + E++    V ++GK + ++  A D ++EE++   L N KVQ
Sbjct  768  LVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQ  809


 Score =  177 bits (655),  Expect = 3e-45, Method: Compositional matrix adjust.
 Identities = 88/145 (61%), Positives = 118/145 (82%), Gaps = 0/145 (0%)

Query  1    MSEYQFRETEKKWQAYWEKNQIFKAEDDFTKPKYYTLDMFPYPSGAGLHVGHPLGYIASD  60
            M+ Y+    E KWQA+W  N+ FK+  D +KPK+Y+LDMFPYPSGAGLHVGHP GY A+D
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   IVARYKKQQGFNVLHPMGFDSFGLPAEQYAIQTGQHPAITTEENINRYIEQLKNIGFAYD  120
            I++R+K+ QG NVLHPMG D+FGLPAEQYA++TG++PA  T ENI  +  Q++ +GF+YD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WEREVRTSDPSFYKWTQWIFSLLFN  145
            W+REV T+DP++YKWTQWIF+ L++
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYE  145

1796) Pedsa_0250 in NC_015177


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  424 bits (1598),  Expect = 1e-119, Method: Compositional matrix adjust.
 Identities = 307/715 (43%), Positives = 449/715 (63%), Gaps = 56/715 (7%)

Query  205  LAFLKESTVNWCAALGTVLANDEVI-GGFSERGGHPVEQKKMMQWSMRITAYAERLLKGL  263
            LA+  E  VNW   LGT +AN+EV+ +G SERGG PV +K M QW ++ITAYAERLL +L
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  264  DQIDWPEPLKEIQRNWIGKSVGAMVDFQLADADYKIQVFTTRVDTIYGVSFLVIAPEHEL  323
            +++DWPE++K++QRNWIGKS GA V F++ D+D  + VFTTR DT++G ++ V+APEH L
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  324  VSqitteeqkteieqyiqqtKKKSELDRMADTKTVSGAFTGAYAINPLNGEKVPVWIADY  383
            V  ITT +Q   + +Y +Q+  KS+L R   +K  +G  TG+YAINP+NG  +PVWIADY
Sbjct  268  VDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAINPVNGKEMPVWIADY  327

Query  384  VLAGYGTGAVMAVPSGDQRDYLFASHFNLPIIQILDTQVLDGQADPTKEGQYINSGIING  443
            VLA+YGTGA+MAVP+ D+RD  FA +FNL II +L+   ++ +A  T +G  INS++++G
Sbjct  328  VLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVE-EAAFTEDGLHINSDFLDG  386

Query  444  LGYKEATAKLISFLEEKEQGYAKVNYRMRDAIFGRQRYWGEPVP-VYFKNGLPYLIDESE  502
            L+   A AK++  LE    G  +V YR+RD +F+RQRYWGEP+P +   +G +  + ESE
Sbjct  387  LDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESE  446

Query  503  LPLLLPEVDKYLPTETGEPPLGRAKDW-------KYKGEYEYELSTMPGWAGSSWYWYRY  555
            LPL+LP      P+ TGE+PL+   DW         KG    E +TMP WAGSSWY  RY
Sbjct  447  LPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVKG--RRETNTMPQWAGSSWYYLRY  504

Query  556  MDAHNDKEFASEKAIEYWKDVDLYIGGSEHATGHLLYSRFWNKFLKDLGFAKEEEPFKKL  615
            +D+HN   +A E  +  W  VD+Y+GG+EHA  HLLY+RFW+K L DLG     EPF+KL
Sbjct  505  IDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKL  564

Query  616  INQGMIQGRSNFVYRIMSEDGRGTNTYVSNGLKNNYQTTALHVDVNIVENDILNLDKFRN  675
            +NQGMI G S   YR    D+RG+                           ++  DK  +
Sbjct  565  FNQGMILGTS---YR----DSRGA---------------------------LVATDKVEK  590

Query  676  WREEFKDAEFVLEEGKYICGVEVEKMSKSKFNVVNPDDLIERYGADTLRMYEMFLGPLEQ  735
            +   F    F +E G  +      KMSKS  NVVNPDD++E+YGADTLR+YEMF+GPL+ 
Sbjct  591  RDGSF----FHVETGEEL-EQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  736  SKPWNTNGIEGVFKFLRKFWKLFHNDAFEFVVSNDEPTKQELKSLHKLIKKVEDDVERFS  795
            S +W+ +G+EG  KFL +  +L+        ++++++   + K  +  +K V ++V++  
Sbjct  646  SIAWSEEGLEGSRKFLDRVYRLITTKE----ITEENSGALD-KVYNETVKAVTEQVDQMK  700

Query  796  FNTSVSSFMITVNELTDLKCNKRAILQEMVILLSSYAPHITEELWTLLGNTEGTLSKARF  855
            FNT+++ +M+ VN             +  V L++++APH+ EELW  L  +  ++S    
Sbjct  701  FNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPW  760

Query  856  PKFNAEYLVESEFNYPISINGKTKTNLSFGLDLDNVEIEKLVLANEQVQKYLDGK  910
            P ++   LVE++ +  + I+GK K++L  + DL   E++ + LANE+VQ  + GK
Sbjct  761  PSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGK  815


 Score =  181 bits (670),  Expect = 2e-46, Method: Compositional matrix adjust.
 Identities = 91/142 (65%), Positives = 116/142 (82%), Gaps = 0/142 (0%)

Query  3    YQFKNIEKKWQKFWADNETYKVEVDNSKPKYYVLDMFPYPSGAGLHVGHPLGYIASDIFS  62
            Y+   IE KWQ FWADN+T+K   D SKPK+Y LDMFPYPSGAGLHVGHP GY A+DI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRLKGFNVLHPMGYDSFGLPAEQYAIQTGQHPAITTGTNINRYREQLDNLGFSFDWSK  122
            R+KR +G NVLHPMG D+FGLPAEQYA++TG++PA  T+ NI  ++ Q++ LGFS+DW +
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVRTSSPDYYKWTQWIFMQLFN  144
            EV T+ P+YYKWTQWIF +L++
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYE  145

1797) leuS in NC_002950


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  423 bits (1591),  Expect = 3e-119, Method: Compositional matrix adjust.
 Identities = 300/702 (43%), Positives = 442/702 (63%), Gaps = 55/702 (7%)

Query  204  LAYLGDTMVNWCPALGTVLANDEV-KDGVSERGGHPVEQKKMRQWCLRVSAYAERLLHDL  262
            LAY ++  VNW   LGT +AN+EV  DG SERGG PV +K MRQW L+++AYAERLL+DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  263  ETLDWTESLKETQRNWIGRSEGAEMEFRLAGKDCTFTIFTTRADTIFGVTFMVLAPesel  322
            E +DW ES+K+ QRNWIG+S GA++ F++ + D  FT+FTTR+DT+FG T+ VLAPE  L
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  323  veevtteeQRAAVetyltetkrrtererIS-DKRVSGVFSGSYAINPLTGKEIPIWISDY  381
            V+ +TT +Q  AV  Y  ++  +++  R    K  +GV +GSYAINP+ GKE+P+WI+DY
Sbjct  268  VDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAINPVNGKEMPVWIADY  327

Query  382  VLAGYGTGAIMAVPAHDTRDFAFARHFDLPIVQVVVPEGEPATDPATWEDAKDSKSGIMV  441
            VLA+YGTGAIMAVPAHD RD  FA++F+L I+ V+  EG    ++A       +  G+ +
Sbjct  328  VLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL--EGGNVEEAAF------TEDGLHI  379

Query  442  NSDFLNGLSVEDAIAQTKEYIREKHLGCVKVNYRLRDAIFSRQRYWGEPFPIYY-KEGMP  500
            NSDFL+GL    AIA+  E +    +G  +V YRLRD +FSRQRYWGEP+PI    +G +
Sbjct  380  NSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTS  439

Query  501  HALDEDRLPLRLPEVDKFLPTESGEPPLGRATGW---HTAEGY--PYELSTMPGFAGSSA  555
             A+ E  LPL LP    + P+ +GE+PL+  T+W      +G     E +TMP  AGSS 
Sbjct  440  TAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVKGRRETNTMPQWAGSSW  499

Query  556  YYLRYMDPQNDTALVSRSANEYWRHVDLYIGGTEHATGHLIYSRFWNKFLFDLGIVCEAE  615
            YYLRY+DP+N   L        W  VD+Y+GG+EHA  HL+Y+RFW+K L+DLG+V   E
Sbjct  500  YYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKE  559

Query  616  PFRKLVNQGMIQGRSNFVYRIKNTNTFVSYGLREQYEVTPLHVDVNIVSNDQLDIDRFRA  675
            PF+KL NQGMI G S   YR  +  ++V+ +  E+ + + +HV+    + ++L+      
Sbjct  560  PFQKLFNQGMILGTS---YR-DSRGALVATDKVEKRDGSFFHVE----TGEELEQAP---  608

Query  676  WRPEYTSAEFILEDGKYICGWAIEKMSKSMFNVVNPDDIIARYGADTLRLYEMFLGPLEQ  735
                                    KMSKS+ NVVNPDD++ +YGADTLR+YEMF+GPL+ 
Sbjct  609  -----------------------AKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  736  SKPWDTNGIDGVHRFLKKFWALYYNTDGIRVTDTAPTKEELKSLHKLIKKVGQDIESFSF  795
            S +W  +G++G ++FL +   +Y       +T+  +   + K  +  +K V ++++   F
Sbjct  646  SIAWSEEGLEGSRKFLDR---VYRLITTKEITEENSGALD-KVYNETVKAVTEQVDQMKF  701

Query  796  NTSIPAFMICVNELTAAKTTSRAILCPLLTVLSPFAPHITEWLWQELGVEGSIVT-ATWP  854
            NT+I+ +M+ VN               ++ +++PFAPH+ E LWQ L   G  ++   WP
Sbjct  702  NTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWP  761

Query  855  EYNEEYLVESCVRYPVSFNGKVRFNIELPADMSKEDVEQAAL  896
             Y+E  LVE+ V   V ++GKV+ ++ ++ D+S+E++++ AL
Sbjct  762  SYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVAL  803


 Score =  163 bits (603),  Expect = 4e-41, Method: Compositional matrix adjust.
 Identities = 84/142 (60%), Positives = 110/142 (78%), Gaps = 0/142 (0%)

Query  3    YNFQEIEKRVQGQWRKDKVYRVAEDTSKKPFYVLDMFPYPSGAGLHVGHPLGYIASDIFS  62
            Y+   IE + Q+ W  +  ++ + D+SK  FY LDMFPYPSGAGLHVGHP GY A+DI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRLRGFNVLHPMGYDAFGLPAEQYAIQTGQHPEKTTEENTARYREQLDKIGFSYDWER  122
            R+KR +G NVLHPMG DAFGLPAEQYA++TG++P   T EN A ++ Q++ +GFSYDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EIRTCDPNYYKWTQWAFLKMFD  144
            E+ T DPNYYKWTQW F K+++
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYE  145

1798) RA0C_1213 in NC_017045


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  423 bits (1591),  Expect = 4e-119, Method: Compositional matrix adjust.
 Identities = 302/723 (42%), Positives = 445/723 (62%), Gaps = 57/723 (7%)

Query  209  LAYRAETTVNWCPALGTVLANDEV-KDGKSERGGYPVFQKKMMQWSMRITAYSERLLQGL  267
            LAY AE  VNW   LGT +AN+EV  DG SERGGYPV +K M QW ++ITAY+ERLL++L
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  268  NTLDWPQPLKDSQEYWIGKSQGALVQFSVDGLEGESIEVFTTRPDTIFGVSFMVLAPEHH  327
            + +DWP+++KD Q  WIGKS GA V F V + + + + VFTTRPDT+FG ++ VLAPEH 
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKD-FTVFTTRPDTLFGATYAVLAPEHA  266

Query  328  LVEKLTTEEQKNAINQYIEETSKKTERDRMADVKSVSGAFTGSYVTHPFTKELIPIYISD  387
            LV+ +TT +Q +A+ +Y  ++S K++  R    K  +G  TGSY  +P     +P+ I+D
Sbjct  267  LVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAINPVNGKEMPVWIAD  326

Query  388  YVLMGYGTGAVMAVPAHDDRDHRFAKYFGLPIKKVVATDIDVQEESFDSKESTCVNSDFL  447
            YVL +YGTGA+MAVPAHD+RD  FAK F L I  V+  + +V+E +F + ++  +NSDFL
Sbjct  327  YVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGG-NVEEAAF-TEDGLHINSDFL  384

Query  448  DGLNYKDAKQKIIQEIEKLGIGKGTTNYRQRDAIFSRQRYWGEPVPIYYKEEMPYTlpls  507
            DGL+   A  K+++ +E  G+G+    YR RD +FSRQRYWGEP+PI   E+   T    
Sbjct  385  DGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPE  444

Query  508  alplelpeveKYL-PTEDGDPPLGNAKTFAWDEVNQKVTFVDLIDNKTVFPMELSTMPGW  566
            +    +  V K + P+  G++PL+N     W EV +        ++      E +TMP W
Sbjct  445  SELPLVLPVTKDIRPSGTGESPLANVT--DWLEVTR--------EDGVKGRRETNTMPQW  494

Query  567  AGSSWYFLRYMDSTNDEVFCAKEKSDYWGQVDLYIGGSEHATGHLLYARFWNMFLKDRGF  626
            AGSSWY+LRY+D+ N E +   E    W  VD+Y+GG+EHA  HLLYARFW+  L D G 
Sbjct  495  AGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGV  554

Query  627  INHEEPFQKLINQGMILGMSAFVFRVDGTNQFVSKNLAKDYQTQKIHVDVALLKGTSDEL  686
            +   EPFQKL+NQGMILG S   +R D+   +V+ +     +   +HV+      T++EL
Sbjct  555  VPTKEPFQKLFNQGMILGTS---YR-DSRGALVATDKVEKRDGSFFHVE------TGEEL  604

Query  687  DTEAFKQWRPEFKDAEFILEGGKYITEREVEKMSKSKYNVVNPDDICEEYGADCLRLYEM  746
            +  +                           KMSKS  NVVNPDD+ E+YGAD LR+YEM
Sbjct  605  EQAP--------------------------AKMSKSLKNVVNPDDVVEQYGADTLRVYEM  638

Query  747  FLGPLEQSKPWNTQGLSGVYGFLKKFYNLYFVDGDEVNISDEEPTKEEYKVLHTLIKKVK  806
            F+GPL+ S +W+ +GL G   FL + Y L        +I++E++   + KV +  +K V 
Sbjct  639  FMGPLDASIAWSEEGLEGSRKFLDRVYRLITTK----EITEENSGALD-KVYNETVKAVT  693

Query  807  FDIDNFSFNTSVSSFMIAVNELQKLKTNKRKILEPLAVVISPYAPHICEELWQ-LLGYNE  865
             ++D+  FNT+++ +M+ VN  +K           +  +I+P+APH+ EELWQ L +  E
Sbjct  694  EQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGE  753

Query  866  SIEFVEFPVLNEGYLKEDEIEYPVSFNGKMRFKLPLSADLSKEEIEKIAIENDKVLQYLD  925
            SI +V  P  +E+ L E+++E  V ++GK++ KL ++ DLS+EE++ +A+ N+KV   + 
Sbjct  754  SISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIA  813

Query  926  GNG  928
            G++
Sbjct  814  GKD  816


 Score =  178 bits (659),  Expect = 2e-45, Method: Compositional matrix adjust.
 Identities = 89/148 (61%), Positives = 117/148 (80%), Gaps = 5/148 (3%)

Query  2    FYNHQEIEKKWQKYWDDNQIFKSQEPKSGVEKNKPKFYVLDMFPYPSGAGLHVGHPLGYI  61
            FY+H  IE KWQ +W DN+ FK+     G + +KPKFY LDMFPYPSGAGLHVGHP GY 
Sbjct  3    FYDHTAIEPKWQAFWADNHTFKT-----GTDASKPKFYALDMFPYPSGAGLHVGHPEGYT  57

Query  62   ASDIYARYKRHQGYNVLHPIGYDSFGLPAEQYAIQTGQHPAVTTENNITRYEEQLRKIGF  121
            A+DI +R+KR QG NVLHP+G D+FGLPAEQYA++TG++PA  T +NI+ +  Q+  +GF
Sbjct  58   ATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGF  117

Query  122  SFDWSRELRTSDASYYKWTQWIFIQLFH  149
            S+DW RE+ T+D++YYKWTQWIF +L++
Sbjct  118  SYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1799) Riean_0951 in NC_014738


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  423 bits (1591),  Expect = 4e-119, Method: Compositional matrix adjust.
 Identities = 302/723 (42%), Positives = 445/723 (62%), Gaps = 57/723 (7%)

Query  209  LAYRAETTVNWCPALGTVLANDEV-KDGKSERGGYPVFQKKMMQWSMRITAYSERLLQGL  267
            LAY AE  VNW   LGT +AN+EV  DG SERGGYPV +K M QW ++ITAY+ERLL++L
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  268  NTLDWPQPLKDSQEYWIGKSQGALVQFSVDGLEGESIEVFTTRPDTIFGVSFMVLAPEHH  327
            + +DWP+++KD Q  WIGKS GA V F V + + + + VFTTRPDT+FG ++ VLAPEH 
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKD-FTVFTTRPDTLFGATYAVLAPEHA  266

Query  328  LVEKLTTEEQKNAINQYIEETSKKTERDRMADVKSVSGAFTGSYVTHPFTKELIPIYISD  387
            LV+ +TT +Q +A+ +Y  ++S K++  R    K  +G  TGSY  +P     +P+ I+D
Sbjct  267  LVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAINPVNGKEMPVWIAD  326

Query  388  YVLMGYGTGAVMAVPAHDDRDHRFAKYFGLPIKKVVATDIDVQEESFDSKESTCVNSDFL  447
            YVL +YGTGA+MAVPAHD+RD  FAK F L I  V+  + +V+E +F + ++  +NSDFL
Sbjct  327  YVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGG-NVEEAAF-TEDGLHINSDFL  384

Query  448  DGLNYKDAKQKIIQEIEKLGIGKGTTNYRQRDAIFSRQRYWGEPVPIYYKEEMPYTlpls  507
            DGL+   A  K+++ +E  G+G+    YR RD +FSRQRYWGEP+PI   E+   T    
Sbjct  385  DGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPE  444

Query  508  alplelpeveKYL-PTEDGDPPLGNAKTFAWDEVNQKVTFVDLIDNKTVFPMELSTMPGW  566
            +    +  V K + P+  G++PL+N     W EV +        ++      E +TMP W
Sbjct  445  SELPLVLPVTKDIRPSGTGESPLANVT--DWLEVTR--------EDGVKGRRETNTMPQW  494

Query  567  AGSSWYFLRYMDSTNDEVFCAKEKSDYWGQVDLYIGGSEHATGHLLYARFWNMFLKDRGF  626
            AGSSWY+LRY+D+ N E +   E    W  VD+Y+GG+EHA  HLLYARFW+  L D G 
Sbjct  495  AGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGV  554

Query  627  INHEEPFQKLINQGMILGMSAFVFRVDGTNQFVSKNLAKDYQTQKIHVDVALLKGTSDEL  686
            +   EPFQKL+NQGMILG S   +R D+   +V+ +     +   +HV+      T++EL
Sbjct  555  VPTKEPFQKLFNQGMILGTS---YR-DSRGALVATDKVEKRDGSFFHVE------TGEEL  604

Query  687  DTEAFKQWRPEFKDAEFILEGGKYITEREVEKMSKSKYNVVNPDDICEEYGADCLRLYEM  746
            +  +                           KMSKS  NVVNPDD+ E+YGAD LR+YEM
Sbjct  605  EQAP--------------------------AKMSKSLKNVVNPDDVVEQYGADTLRVYEM  638

Query  747  FLGPLEQSKPWNTQGLSGVYGFLKKFYNLYFVDGDEVNISDEEPTKEEYKVLHTLIKKVK  806
            F+GPL+ S +W+ +GL G   FL + Y L        +I++E++   + KV +  +K V 
Sbjct  639  FMGPLDASIAWSEEGLEGSRKFLDRVYRLITTK----EITEENSGALD-KVYNETVKAVT  693

Query  807  FDIDNFSFNTSVSSFMIAVNELQKLKTNKRKILEPLAVVISPYAPHICEELWQ-LLGYNE  865
             ++D+  FNT+++ +M+ VN  +K           +  +I+P+APH+ EELWQ L +  E
Sbjct  694  EQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGE  753

Query  866  SIEFVEFPVLNEGYLKEDEIEYPVSFNGKMRFKLPLSADLSKEEIEKIAIENDKVLQYLD  925
            SI +V  P  +E+ L E+++E  V ++GK++ KL ++ DLS+EE++ +A+ N+KV   + 
Sbjct  754  SISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIA  813

Query  926  GNG  928
            G++
Sbjct  814  GKD  816


 Score =  178 bits (659),  Expect = 2e-45, Method: Compositional matrix adjust.
 Identities = 89/148 (61%), Positives = 117/148 (80%), Gaps = 5/148 (3%)

Query  2    FYNHQEIEKKWQKYWDDNQIFKSQEPKSGVEKNKPKFYVLDMFPYPSGAGLHVGHPLGYI  61
            FY+H  IE KWQ +W DN+ FK+     G + +KPKFY LDMFPYPSGAGLHVGHP GY 
Sbjct  3    FYDHTAIEPKWQAFWADNHTFKT-----GTDASKPKFYALDMFPYPSGAGLHVGHPEGYT  57

Query  62   ASDIYARYKRHQGYNVLHPIGYDSFGLPAEQYAIQTGQHPAVTTENNITRYEEQLRKIGF  121
            A+DI +R+KR QG NVLHP+G D+FGLPAEQYA++TG++PA  T +NI+ +  Q+  +GF
Sbjct  58   ATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGF  117

Query  122  SFDWSRELRTSDASYYKWTQWIFIQLFH  149
            S+DW RE+ T+D++YYKWTQWIF +L++
Sbjct  118  SYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1800) G148_0667 in NC_020125


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  423 bits (1591),  Expect = 4e-119, Method: Compositional matrix adjust.
 Identities = 302/723 (42%), Positives = 445/723 (62%), Gaps = 57/723 (7%)

Query  209  LAYRAETTVNWCPALGTVLANDEV-KDGKSERGGYPVFQKKMMQWSMRITAYSERLLQGL  267
            LAY AE  VNW   LGT +AN+EV  DG SERGGYPV +K M QW ++ITAY+ERLL++L
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  268  NTLDWPQPLKDSQEYWIGKSQGALVQFSVDGLEGESIEVFTTRPDTIFGVSFMVLAPEHH  327
            + +DWP+++KD Q  WIGKS GA V F V + + + + VFTTRPDT+FG ++ VLAPEH 
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKD-FTVFTTRPDTLFGATYAVLAPEHA  266

Query  328  LVEKLTTEEQKNAINQYIEETSKKTERDRMADVKSVSGAFTGSYVTHPFTKELIPIYISD  387
            LV+ +TT +Q +A+ +Y  ++S K++  R    K  +G  TGSY  +P     +P+ I+D
Sbjct  267  LVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAINPVNGKEMPVWIAD  326

Query  388  YVLMGYGTGAVMAVPAHDDRDHRFAKYFGLPIKKVVATDIDVQEESFDSKESTCVNSDFL  447
            YVL +YGTGA+MAVPAHD+RD  FAK F L I  V+  + +V+E +F + ++  +NSDFL
Sbjct  327  YVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGG-NVEEAAF-TEDGLHINSDFL  384

Query  448  DGLNYKDAKQKIIQEIEKLGIGKGTTNYRQRDAIFSRQRYWGEPVPIYYKEEMPYTlpls  507
            DGL+   A  K+++ +E  G+G+    YR RD +FSRQRYWGEP+PI   E+   T    
Sbjct  385  DGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPE  444

Query  508  alplelpeveKYL-PTEDGDPPLGNAKTFAWDEVNQKVTFVDLIDNKTVFPMELSTMPGW  566
            +    +  V K + P+  G++PL+N     W EV +        ++      E +TMP W
Sbjct  445  SELPLVLPVTKDIRPSGTGESPLANVT--DWLEVTR--------EDGVKGRRETNTMPQW  494

Query  567  AGSSWYFLRYMDSTNDEVFCAKEKSDYWGQVDLYIGGSEHATGHLLYARFWNMFLKDRGF  626
            AGSSWY+LRY+D+ N E +   E    W  VD+Y+GG+EHA  HLLYARFW+  L D G 
Sbjct  495  AGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGV  554

Query  627  INHEEPFQKLINQGMILGMSAFVFRVDGTNQFVSKNLAKDYQTQKIHVDVALLKGTSDEL  686
            +   EPFQKL+NQGMILG S   +R D+   +V+ +     +   +HV+      T++EL
Sbjct  555  VPTKEPFQKLFNQGMILGTS---YR-DSRGALVATDKVEKRDGSFFHVE------TGEEL  604

Query  687  DTEAFKQWRPEFKDAEFILEGGKYITEREVEKMSKSKYNVVNPDDICEEYGADCLRLYEM  746
            +  +                           KMSKS  NVVNPDD+ E+YGAD LR+YEM
Sbjct  605  EQAP--------------------------AKMSKSLKNVVNPDDVVEQYGADTLRVYEM  638

Query  747  FLGPLEQSKPWNTQGLSGVYGFLKKFYNLYFVDGDEVNISDEEPTKEEYKVLHTLIKKVK  806
            F+GPL+ S +W+ +GL G   FL + Y L        +I++E++   + KV +  +K V 
Sbjct  639  FMGPLDASIAWSEEGLEGSRKFLDRVYRLITTK----EITEENSGALD-KVYNETVKAVT  693

Query  807  FDIDNFSFNTSVSSFMIAVNELQKLKTNKRKILEPLAVVISPYAPHICEELWQ-LLGYNE  865
             ++D+  FNT+++ +M+ VN  +K           +  +I+P+APH+ EELWQ L +  E
Sbjct  694  EQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGE  753

Query  866  SIEFVEFPVLNEGYLKEDEIEYPVSFNGKMRFKLPLSADLSKEEIEKIAIENDKVLQYLD  925
            SI +V  P  +E+ L E+++E  V ++GK++ KL ++ DLS+EE++ +A+ N+KV   + 
Sbjct  754  SISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIA  813

Query  926  GNG  928
            G++
Sbjct  814  GKD  816


 Score =  178 bits (659),  Expect = 2e-45, Method: Compositional matrix adjust.
 Identities = 89/148 (61%), Positives = 117/148 (80%), Gaps = 5/148 (3%)

Query  2    FYNHQEIEKKWQKYWDDNQIFKSQEPKSGVEKNKPKFYVLDMFPYPSGAGLHVGHPLGYI  61
            FY+H  IE KWQ +W DN+ FK+     G + +KPKFY LDMFPYPSGAGLHVGHP GY 
Sbjct  3    FYDHTAIEPKWQAFWADNHTFKT-----GTDASKPKFYALDMFPYPSGAGLHVGHPEGYT  57

Query  62   ASDIYARYKRHQGYNVLHPIGYDSFGLPAEQYAIQTGQHPAVTTENNITRYEEQLRKIGF  121
            A+DI +R+KR QG NVLHP+G D+FGLPAEQYA++TG++PA  T +NI+ +  Q+  +GF
Sbjct  58   ATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGF  117

Query  122  SFDWSRELRTSDASYYKWTQWIFIQLFH  149
            S+DW RE+ T+D++YYKWTQWIF +L++
Sbjct  118  SYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1801) RIA_1286 in NC_017569


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  423 bits (1591),  Expect = 4e-119, Method: Compositional matrix adjust.
 Identities = 302/723 (42%), Positives = 445/723 (62%), Gaps = 57/723 (7%)

Query  209  LAYRAETTVNWCPALGTVLANDEV-KDGKSERGGYPVFQKKMMQWSMRITAYSERLLQGL  267
            LAY AE  VNW   LGT +AN+EV  DG SERGGYPV +K M QW ++ITAY+ERLL++L
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  268  NTLDWPQPLKDSQEYWIGKSQGALVQFSVDGLEGESIEVFTTRPDTIFGVSFMVLAPEHH  327
            + +DWP+++KD Q  WIGKS GA V F V + + + + VFTTRPDT+FG ++ VLAPEH 
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKD-FTVFTTRPDTLFGATYAVLAPEHA  266

Query  328  LVEKLTTEEQKNAINQYIEETSKKTERDRMADVKSVSGAFTGSYVTHPFTKELIPIYISD  387
            LV+ +TT +Q +A+ +Y  ++S K++  R    K  +G  TGSY  +P     +P+ I+D
Sbjct  267  LVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAINPVNGKEMPVWIAD  326

Query  388  YVLMGYGTGAVMAVPAHDDRDHRFAKYFGLPIKKVVATDIDVQEESFDSKESTCVNSDFL  447
            YVL +YGTGA+MAVPAHD+RD  FAK F L I  V+  + +V+E +F + ++  +NSDFL
Sbjct  327  YVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGG-NVEEAAF-TEDGLHINSDFL  384

Query  448  DGLNYKDAKQKIIQEIEKLGIGKGTTNYRQRDAIFSRQRYWGEPVPIYYKEEMPYTlpls  507
            DGL+   A  K+++ +E  G+G+    YR RD +FSRQRYWGEP+PI   E+   T    
Sbjct  385  DGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPE  444

Query  508  alplelpeveKYL-PTEDGDPPLGNAKTFAWDEVNQKVTFVDLIDNKTVFPMELSTMPGW  566
            +    +  V K + P+  G++PL+N     W EV +        ++      E +TMP W
Sbjct  445  SELPLVLPVTKDIRPSGTGESPLANVT--DWLEVTR--------EDGVKGRRETNTMPQW  494

Query  567  AGSSWYFLRYMDSTNDEVFCAKEKSDYWGQVDLYIGGSEHATGHLLYARFWNMFLKDRGF  626
            AGSSWY+LRY+D+ N E +   E    W  VD+Y+GG+EHA  HLLYARFW+  L D G 
Sbjct  495  AGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGV  554

Query  627  INHEEPFQKLINQGMILGMSAFVFRVDGTNQFVSKNLAKDYQTQKIHVDVALLKGTSDEL  686
            +   EPFQKL+NQGMILG S   +R D+   +V+ +     +   +HV+      T++EL
Sbjct  555  VPTKEPFQKLFNQGMILGTS---YR-DSRGALVATDKVEKRDGSFFHVE------TGEEL  604

Query  687  DTEAFKQWRPEFKDAEFILEGGKYITEREVEKMSKSKYNVVNPDDICEEYGADCLRLYEM  746
            +  +                           KMSKS  NVVNPDD+ E+YGAD LR+YEM
Sbjct  605  EQAP--------------------------AKMSKSLKNVVNPDDVVEQYGADTLRVYEM  638

Query  747  FLGPLEQSKPWNTQGLSGVYGFLKKFYNLYFVDGDEVNISDEEPTKEEYKVLHTLIKKVK  806
            F+GPL+ S +W+ +GL G   FL + Y L        +I++E++   + KV +  +K V 
Sbjct  639  FMGPLDASIAWSEEGLEGSRKFLDRVYRLITTK----EITEENSGALD-KVYNETVKAVT  693

Query  807  FDIDNFSFNTSVSSFMIAVNELQKLKTNKRKILEPLAVVISPYAPHICEELWQ-LLGYNE  865
             ++D+  FNT+++ +M+ VN  +K           +  +I+P+APH+ EELWQ L +  E
Sbjct  694  EQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGE  753

Query  866  SIEFVEFPVLNEGYLKEDEIEYPVSFNGKMRFKLPLSADLSKEEIEKIAIENDKVLQYLD  925
            SI +V  P  +E+ L E+++E  V ++GK++ KL ++ DLS+EE++ +A+ N+KV   + 
Sbjct  754  SISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIA  813

Query  926  GNG  928
            G++
Sbjct  814  GKD  816


 Score =  178 bits (659),  Expect = 2e-45, Method: Compositional matrix adjust.
 Identities = 89/148 (61%), Positives = 117/148 (80%), Gaps = 5/148 (3%)

Query  2    FYNHQEIEKKWQKYWDDNQIFKSQEPKSGVEKNKPKFYVLDMFPYPSGAGLHVGHPLGYI  61
            FY+H  IE KWQ +W DN+ FK+     G + +KPKFY LDMFPYPSGAGLHVGHP GY 
Sbjct  3    FYDHTAIEPKWQAFWADNHTFKT-----GTDASKPKFYALDMFPYPSGAGLHVGHPEGYT  57

Query  62   ASDIYARYKRHQGYNVLHPIGYDSFGLPAEQYAIQTGQHPAVTTENNITRYEEQLRKIGF  121
            A+DI +R+KR QG NVLHP+G D+FGLPAEQYA++TG++PA  T +NI+ +  Q+  +GF
Sbjct  58   ATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGF  117

Query  122  SFDWSRELRTSDASYYKWTQWIFIQLFH  149
            S+DW RE+ T+D++YYKWTQWIF +L++
Sbjct  118  SYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1802) leuS in NC_010729


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  422 bits (1590),  Expect = 5e-119, Method: Compositional matrix adjust.
 Identities = 299/704 (43%), Positives = 442/704 (63%), Gaps = 55/704 (7%)

Query  204  LAYLGDTMVNWCPALGTVLANDEV-KDGVSERGGHPVEQKKMRQWCLRVSAYAERLLHDL  262
            LAY ++  VNW   LGT +AN+EV  DG SERGG PV +K MRQW L+++AYAERLL+DL
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  263  ETLDWTESLKETQRNWIGRSEGAEMEFRLAGKDCTFTIFTTRADTIFGVTFMVLAPesel  322
            E +DW ES+K+ QRNWIG+S GA++ F++ + D  FT+FTTR+DT+FG T+ VLAPE  L
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  323  veevtteeQRAAVetyltetkrrtererIS-DKRVSGVFSGSYAINPLTGKEIPIWISDY  381
            V+ +TT +Q  AV  Y  ++  +++  R    K  +GV +GSYAINP+ GKE+P+WI+DY
Sbjct  268  VDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAINPVNGKEMPVWIADY  327

Query  382  VLAGYGTGAIMAVPAHDTRDFAFARHFDLPIVQVVVPEGETATDPATWEDAKDSKSGIMV  441
            VLA+YGTGAIMAVPAHD RD  FA++F+L I+ V+  EG    ++A       +  G+ +
Sbjct  328  VLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL--EGGNVEEAAF------TEDGLHI  379

Query  442  NSDFLNGLSVEDAIAQTKEYIREKHLGCVKVNYRLRDAIFSRQRYWGEPFPIYY-KEGMP  500
            NSDFL+GL    AIA+  E +    +G  +V YRLRD +FSRQRYWGEP+PI    +G +
Sbjct  380  NSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTS  439

Query  501  HALDEDRLPLRLPEVDKFLPTESGEPPLGRATGW---HTAEGY--PYELSTMPGFAGSSA  555
             A+ E  LPL LP    + P+ +GE+PL+  T+W      +G     E +TMP  AGSS 
Sbjct  440  TAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVKGRRETNTMPQWAGSSW  499

Query  556  YYLRYMDPQNDTALVSRSANEYWRHVDLYIGGTEHATGHLIYSRFWNKFLFDLGIVCEAE  615
            YYLRY+DP+N   L        W  VD+Y+GG+EHA  HL+Y+RFW+K L+DLG+V   E
Sbjct  500  YYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKE  559

Query  616  PFRKLVNQGMIQGRSNFVYRIKNTNTFVSYGLREQYEVTPLHVDVNIVSNDQLDIDRFRA  675
            PF+KL NQGMI G S   YR  +  ++V+ +  E+ + + +HV+    + ++L+      
Sbjct  560  PFQKLFNQGMILGTS---YR-DSRGALVATDKVEKRDGSFFHVE----TGEELEQAP---  608

Query  676  WRPEYASAEFILEDGKYICGWAIEKMSKSMFNVVNPDDIIARYGADTLRLYEMFLGPLEQ  735
                                    KMSKS+ NVVNPDD++ +YGADTLR+YEMF+GPL+ 
Sbjct  609  -----------------------AKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDA  645

Query  736  SKPWDTNGIDGVHRFLKKFWALYYNADGIRVTDTAPTKEELKSLHKLIKKVGQDIESFSF  795
            S +W  +G++G ++FL +   +Y       +T+  +   + K  +  +K V ++++   F
Sbjct  646  SIAWSEEGLEGSRKFLDR---VYRLITTKEITEENSGALD-KVYNETVKAVTEQVDQMKF  701

Query  796  NTSIPAFMICVNELTAAKTTSRAILCPLLTVLSPFAPHITEWLWQELGVEGSIVT-ATWP  854
            NT+I+ +M+ VN               ++ +++PFAPH+ E LWQ L   G  ++   WP
Sbjct  702  NTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWP  761

Query  855  EYNEEYLVESCVRYPVSFNGKVRFNIELPADMSKKDVEQAALTA  898
             Y+E  LVE+ V   V ++GKV+ ++ ++ D+S+ ++++ AL+ 
Sbjct  762  SYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALAN  805


 Score =  163 bits (603),  Expect = 4e-41, Method: Compositional matrix adjust.
 Identities = 84/142 (60%), Positives = 110/142 (78%), Gaps = 0/142 (0%)

Query  3    YNFQEIEKRVQGQWRKDKVYRVAEDTSKKPFYVLDMFPYPSGAGLHVGHPLGYIASDIFS  62
            Y+   IE + Q+ W  +  ++ + D+SK  FY LDMFPYPSGAGLHVGHP GY A+DI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRLRGFNVLHPMGYDAFGLPAEQYAIQTGQHPEKTTEENTARYREQLDKIGFSYDWER  122
            R+KR +G NVLHPMG DAFGLPAEQYA++TG++P   T EN A ++ Q++ +GFSYDW+R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EIRTCDPNYYKWTQWAFLKMFD  144
            E+ T DPNYYKWTQW F K+++
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYE  145

1803) B739_0929 in NC_018609


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  422 bits (1587),  Expect = 8e-119, Method: Compositional matrix adjust.
 Identities = 301/722 (42%), Positives = 445/722 (62%), Gaps = 56/722 (7%)

Query  209  LAYRAETTVNWCPALGTVLANDEV-KDGKSERGGYPVFQKKMMQWSMRITAYSERLLQGL  267
            LAY AE  VNW   LGT +AN+EV  DG SERGGYPV +K M QW ++ITAY+ERLL++L
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  268  NTLDWPQPLKDSQEYWIGKSQGALVQFSIDGLEGESVEVFTTRPDTIFGVSFMVLAPEHH  327
            + +DWP+++KD Q  WIGKS GA V F + + + +   VFTTRPDT+FG ++ VLAPEH 
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKD-FTVFTTRPDTLFGATYAVLAPEHA  266

Query  328  LVEKLTTEEQKNAINQYIEETSKKTERDRMADVKSVSGAFTGSYVTHPFTRELIPIYISD  387
            LV+ +TT +Q +A+ +Y  ++S K++  R    K  +G  TGSY  +P     +P+ I+D
Sbjct  267  LVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAINPVNGKEMPVWIAD  326

Query  388  YVLMGYGTGAVMAVPAHDDRDHRFAKYFGLPIKKVVATDIDVQEESFDSKESTCVNSEFL  447
            YVL +YGTGA+MAVPAHD+RD  FAK F L I  V+  + +V+E +F + ++  +NS+FL
Sbjct  327  YVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGG-NVEEAAF-TEDGLHINSDFL  384

Query  448  DGLNYKDAKQKIIQEIEKLGIGKGTTNYRQRDAIFSRQRYWGEPVPIYYKEDMPYTlpls  507
            DGL+   A  K+++ +E  G+G+    YR RD +FSRQRYWGEP+PI   ED   T    
Sbjct  385  DGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPE  444

Query  508  alplelpeveKYL-PTEDGDPPLGNAKTFAWDEVNQRVASVDLIDNKKVFPMELSTMPGW  566
            +    +  V K + P+  G++PL+N     W EV +     D +  ++    E +TMP W
Sbjct  445  SELPLVLPVTKDIRPSGTGESPLANVT--DWLEVTRE----DGVKGRR----ETNTMPQW  494

Query  567  AGSSWYFLRYMDSTNDEVFCAKEKTDYWGQVDLYIGGSEHATGHLLYARFWNMFLKDRGF  626
            AGSSWY+LRY+D+ N E +   E    W  VD+Y+GG+EHA  HLLYARFW+  L D G 
Sbjct  495  AGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGV  554

Query  627  ISHEEPFQKLINQGMILGMSAFVFRVDGTNQFVSKNLAKDYQTQKIHVDVSLLKGTSDEL  686
            ++  EPFQKL+NQGMILG S   +R D+   +V+ +     +   +HV+      T++EL
Sbjct  555  VPTKEPFQKLFNQGMILGTS---YR-DSRGALVATDKVEKRDGSFFHVE------TGEEL  604

Query  687  DTDAFKQWRPEFKDAEFILEGGKYITEREVEKMSKSKYNVVNPDDICEEYGADCLRLYEM  746
            +  +                           KMSKS  NVVNPDD+ E+YGAD LR+YEM
Sbjct  605  EQAP--------------------------AKMSKSLKNVVNPDDVVEQYGADTLRVYEM  638

Query  747  FLGPLEQSKPWNTQGLSGVYGFLKKFYNLYFDGDKVNISDEEPTKEEYKALHTLIKKVKF  806
            F+GPL+ S +W+ +GL G   FL + Y L       +I++E++   + K  +  +K V  
Sbjct  639  FMGPLDASIAWSEEGLEGSRKFLDRVYRLI---TTKEITEENSGALD-KVYNETVKAVTE  694

Query  807  DIDNFSFNTSVSSFMIAVNELQKLKTNKRKILEPLAVVISPYAPHICEELWQ-LLGYNES  865
            ++D+  FNT+++ +M+ VN  +K           +  +I+P+APH+ EELWQ L +  ES
Sbjct  695  QVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGES  754

Query  866  IEFVEFPVLNEEYLKEDEIEYPVSFNGKMRFKLPLPADLSKEEIEKIAIENDKVLQYLDG  925
            I +V  P  +E  L E+++E  V ++GK++ KL ++ DLS+EE++ +A+ N+KV   + G
Sbjct  755  ISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAG  814

Query  926  NG  927
            ++
Sbjct  815  KD  816


 Score =  177 bits (657),  Expect = 2e-45, Method: Compositional matrix adjust.
 Identities = 89/148 (61%), Positives = 116/148 (79%), Gaps = 5/148 (3%)

Query  2    FYNHQEIEKKWQKYWEDNQVFKSQEPKSGVEKNKPKFYVLDMFPYPSGAGLHVGHPLGYI  61
            FY+H  IE KWQ +W DN+ FK+     G + +KPKFY LDMFPYPSGAGLHVGHP GY 
Sbjct  3    FYDHTAIEPKWQAFWADNHTFKT-----GTDASKPKFYALDMFPYPSGAGLHVGHPEGYT  57

Query  62   ASDIYARYKRHQGYNVLHPIGYDSFGLPAEQYAIQTGQHPAVTTENNITRYEEQLRKIGF  121
            A+DI +R+KR QG NVLHP+G D+FGLPAEQYA++TG++PA  T +NI+ +  Q+  +GF
Sbjct  58   ATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGF  117

Query  122  SFDWSRELRTSDTSYYKWTQWIFIQLFH  149
            S+DW RE+ T+D +YYKWTQWIF +L++
Sbjct  118  SYDWDREVNTTDPNYYKWTQWIFTKLYE  145

1804) Solca_2951 in NC_017770


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  420 bits (1580),  Expect = 3e-118, Method: Compositional matrix adjust.
 Identities = 296/735 (41%), Positives = 449/735 (62%), Gaps = 76/735 (10%)

Query  205  LTYLSESVVNWCPALGTVLANDEVI-GGFSERGGHPVEQKKMKQWSMRISAYAERLLNGL  263
            L+Y +E  VNW   LGT +AN+EV+ +G SERGG PV +K M+QW ++I+AYAERLL++L
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  264  DTIDWPEPVREMQRNWIGKSVGALLRFELMSAPENEHGLMELDAHHDVDPETYLSAGVDK  323
            + +DWPE++++MQRNWIGKS GA + F +  +  +                         
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKD-------------------------  242

Query  324  IEVFTTRLDTVYGVTFLVLAPEHELVEKITTPGQKADIEAYIAKTKQKSERDRMADVKTV  383
            + VFTTR DT++G T+ VLAPEH LV+ ITT++Q   +  Y  ++  KS+  R    K  
Sbjct  243  FTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEK  302

Query  384  SGAFTGAYAINPLSGEKVQVWIADYVLAGYGTGAVMAVPSGDERDYRFAKHFNLPIVQIL  443
            +G  TG+YAINP++G  + VWIADYVLA+YGTGA+MAVP+ DERD  FAK+FNL I+ +L
Sbjct  303  TGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVL  362

Query  444  DSQILDETADATKEGKYVNSGMINGMTYAEAMKALVEKIEADGSGKAKTNYRMRDAIFAR  503
            ++  ++E+A  T +G  +NS+ ++G+  A A+  +VE +EA+G G+ +  YR+RD +F+R
Sbjct  363  EGGNVEEAA-FTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSR  421

Query  504  QRYWGEPVPVF-FKNGLPYLIDENDLPLVLPDVDKYLPTETGEPPLARAANW-KYKNEFE  561
            QRYWGEP+P++   +G +  + E++LPLVLP      P+ TGE+PLA  ++W     E  
Sbjct  422  QRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDG  481

Query  562  Y----EHSTMPGWAGSSWYWYRYMDAKNENVFASTEAIDYWKDVDLYIGGSEHATGHLLY  617
                 E +TMP WAGSSWY  RY+D+ N + +A  E +  W  VD+Y+GG+EHA  HLLY
Sbjct  482  VKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLY  541

Query  618  SRFWNKVLKDLGYVKEEEPFKKLINQGMIQGRSNFVYRIIGTNKFVSYGLRKDYDTQALH  677
            +RFW+KVL DLG V   EPF+KL+NQGMI G S   YR                D+++  
Sbjct  542  ARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS---YR----------------DSRG--  580

Query  678  VDVNIVTNDVLDLDKFKNLSPDYVNAEFILEDGKYICGHEVEKMSKSKYNVVSPDDIIDQ  737
                     ++  DK  +    +    F +E G  +  +   KMSKS  NVV+PDD+++Q
Sbjct  581  --------ALVATDKVEKRDGSF----FHVETGEEL-EQAPAKMSKSLKNVVNPDDVVEQ  627

Query  738  YGADTLRMYEMFLGPLEQSKPWNTNGISGVYNFLRKFWNLFYNEQGNFFVSNEEPTKAEL  797
            YGADTLR+YEMF+GPL+ S +W+ +G+ G  +FL +   L+   +    +++E++   + 
Sbjct  628  YGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKE----ITEENSGALD-  682

Query  798  KALHKIIQKVQEDVERFSFNTSVSSYMICVNELTALKCNK--KTILEPLVIALSPYAPHI  855
            K  +  ++ V E+V++  FNT+++  M+ VN  +A K +K        +V  ++P+APH+
Sbjct  683  KVYNETVKAVTEQVDQMKFNTAIAQLMVFVN--AANKEDKLFSDYAKGFVQLIAPFAPHL  740

Query  856  TEELWVLLGNEAGSIIHTSFPEFKAEYLVEDAFDYPISINGKVKTKLNLPLTLEAADVEK  915
             EELW  L   + SI   + P +    LVE+  +  + I+GKVK+KL ++  L   +++ 
Sbjct  741  GEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQE  800

Query  916  AVLESSDVAKYLDGK  930
              L +  V   + GK
Sbjct  801  VALANEKVQAEIAGK  815


 Score =  180 bits (667),  Expect = 4e-46, Method: Compositional matrix adjust.
 Identities = 90/142 (64%), Positives = 115/142 (81%), Gaps = 0/142 (0%)

Query  3    YSFREIEKKWQKFWADNKTFKVDIDSNKPKYYVLDMFPYPSGAGLHVGHPLGYIASDIFT  62
            Y    IE KWQ FWADN TFK + D++KPK+Y LDMFPYPSGAGLHVGHP GY A+DI++
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RFKKLKGFNVLHPMGYDAFGLPAEQYAIQTGQHPAITTDQNTKRYRGQLDRIGFAYDWSR  122
            RFK+ +G NVLHPMG DAFGLPAEQYA++TG++PA  T +N   ++ Q++ +GF+YDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  ELRTCDADYYKWTQWIFMKLFD  144
            E+ T D++YYKWTQWIF KL++
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYE  145

1805) leuS in NC_011565


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  419 bits (1579),  Expect = 3e-118, Method: Compositional matrix adjust.
 Identities = 282/704 (41%), Positives = 439/704 (63%), Gaps = 61/704 (8%)

Query  204  IAYLSDIVVNWCPALGTVLANDEI-SGGISIRGGYTVEQRKMRQWCLRISAYAKRLLEGL  262
            +AY +++ VNW   LGT +AN+E+ ++G S RGGY V ++ MRQW L+I+AYA RLLE+L
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  263  DKIEWTDSLKKMQRNWIGRSEGVELRFKIKDENIEFMIFTTRPETIFGVTFIVIAPESEW  322
            + ++W +S+K MQRNWIG+S G ++ FK+KD + +F +FTTRP+T+FG T+ V+APE   
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHAL  267

Query  323  LTQTIISKKKDSVDSYLNLVKRRTERERIS-NRKVTGVFTGSYAVHPISGETIPIWISDY  381
            +     S + ++V  Y      +++  R    +  TGV TGSYA++P++G  +P+WI+DY
Sbjct  268  VDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAINPVNGKEMPVWIADY  327

Query  382  ILADYGTGAVMAVPAHDSRDYAFAKHFdlpiipliedidiSKESFDIKEGIMTNSDFLNG  441
            +LA YGTGA+MAVPAHD RD  FAK+F+L IIP++E+ ++   +F   +G+  NSDFL+G
Sbjct  328  VLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEAAF-TEDGLHINSDFLDG  386

Query  442  LSVKQAIQKVKEYIKDENLGKIKVNYRLRDAIFSRQRYWGEPFPIYY-KNGIPYAVDEED  500
            L    AI K+ E +  E +G+ +V YRLRD +FSRQRYWGEP+PI    +G + AV E +
Sbjct  387  LDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESE  446

Query  501  LPIKLPEIDKFLPAETGKPPLGRAKNW-------TYKGYPLELTTMPGFAGSSAYYLRYE  553
            LP+ LP    + P+ TG +PL+   +W         KG   E  TMP  AGSS YYLRY 
Sbjct  447  LPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVKG-RRETNTMPQWAGSSWYYLRYI  505

Query  554  DPHNSECLVSSEANEYWQNVDLYIGGIEHATGHLIYSRFWNKFLFDLGIVAKEEPFKKLI  613
            DPHN+E L   E    W  VD+Y+GG EHA  HL+Y+RFW+K L+DLG+V+  EPF+KL+
Sbjct  506  DPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLF  565

Query  614  NQGMIQGRSNFVYRIKNTNTFVSYGLKHQYDVTPIHVDINLVFDDVLNIESFRDWNSEYK  673
            NQGMI G S   YR  +  ++V+ +  ++ D + +HV+    +++               
Sbjct  566  NQGMILGTS---YR-DSRGALVATDKVEKRDGSFFHVETGEELEQ---------------  606

Query  674  NAEFILENGKYVCGWAIEKMSKSMFNTVSPDNIVNRFGADAFRLYEMFLGPLEQSKPWDT  733
                           A  KMSKS+ N V+PD++V+++GAD++R+YEMF+GPL+ S +W  
Sbjct  607  ---------------APAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSE  651

Query  734  KGIDGIARFLKRLWNLFFENDVLKVSNSLPLDKELKSIHKLIKKVSWDIENFSFNTSVAA  793
             G++G  +FL R+  L+  +++   +++ +LDK  +   K +     ++++  FNT++A 
Sbjct  652  EGLEGSRKFLDRVYRLITTKEITEENSG-ALDKVYNETVKAVTE---QVDQMKFNTAIAQ  707

Query  794  FMICINELTLLKCSKHSIL-----SDLVIVLAPFAPHIAEELWHLLGNEATIFD-SQFPK  847
            +M+ +N       +K+  L      ++V ++APFAPH++EELW+ L   +  +     P 
Sbjct  708  LMVFVNA-----ANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPS  762

Query  848  CNEEYLKEENVKYTVSFNGKARFILNFPKKISEENVKDTVLKCE  891
             +E  L E++V   V ++GK +  L  +K +S E++++  L  E
Sbjct  763  YDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806


 Score =  177 bits (657),  Expect = 3e-45, Method: Compositional matrix adjust.
 Identities = 83/142 (59%), Positives = 115/142 (81%), Gaps = 0/142 (0%)

Query  3    YDFDAIEKKWQKYWKENRTYQVNIDRNKPKYYVLDMFPYPSGVGLHVGHPLGYIASDIYA  62
            YD  AIE KWQ +W +N+T++   D +KPK+Y LDMFPYPSG GLHVGHP GY A+DI +
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRLKGFNVLHPMGYDAYGLPAEQYAIQTGQHPSITTKENINRYRKQLDKIGFCFDWDR  122
            R+KR +G NVLHPMG DA+GLPAEQYA++TG++P+  T ENI  +++Q++ +GF +DWDR
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EIRTCDPKYYQWTQWVFIQMFN  144
            E+ T DP+YY+WTQW+F ++++
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYE  145

1806) Runsl_3682 in NC_015703


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  411 bits (1545),  Expect = 2e-115, Method: Compositional matrix adjust.
 Identities = 294/730 (41%), Positives = 450/730 (62%), Gaps = 69/730 (9%)

Query  205  FTFPEESYVNWCPGLGTVLSNDEV-KDGVSERGGFPVERKLMKQWSMRITAYADRLLAGL  263
            +++  E  VNW   LGT ++N+EV  DG SERGG+PV RK M+QW ++ITAYA+RLL +L
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  264  DTIDWPEPLKEQQRNWIGKSVGASVKFAIADLGLPNDSQNPKSKIQNPKCIEVFTTRVDT  323
            + +DWPE++K+ QRNWIGKS GA+V F + D                 K + VFTTR DT
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKVKD---------------TDKDFTVFTTRPDT  252

Query  324  IYGVSFMVLAPEHEWALDLTTPEQKEAVETYIKWAASRSEVDRMA-EKKVTGVFTGSYCI  382
            ++G ++ VLAPEH     +TT++Q EAV  Y + A+ +S++ R    K  TGV TGSY I
Sbjct  253  LFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAI  312

Query  383  NPLNEEKVPIFLADYVLAGYGTGAVMGVPSGDQRDWNFATNFGLPILPILDSQKDIDQQA  442
            NP+N   +P+ +ADYVLA+YGTGA+M+VP+ D+RDW+FA +F L I+P+L++ +   ++A
Sbjct  313  NPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNV--EEA  370

Query  443  DNTKEGRYINSGIINGKTYKEATDTLTKWLEERKLGKGKVQYRLRNAVFSRQRYWGEPVP  502
              T +G  INS++++G     A   +  WLE   +G+ +V YRLR+ +FSRQRYWGEP+P
Sbjct  371  AFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIP  430

Query  503  VYF-KDDIPYLIDESELPLELPKIDKYLPTETGEPPLGRAe-----gwkykgeyeyeLST  556
            +    D+ +  + ESELPL LP      P+ TGE+PL+         +        E +T
Sbjct  431  IIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTREDGVKGRRETNT  490

Query  557  MPGWAGSSWYWYRYMDPQNNDAFASKEAIDYWQRVDFYLGGSEHATGHLLYSRFWNKFLK  616
            MP WAGSSWY  RY+DP+N + +A  E +  W  VD+Y+GG+EHA  HLLY+RFW+K L 
Sbjct  491  MPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWHKVLY  550

Query  617  DLGLVPHEEFAAKLLNQGMIQGRSNFVYRLKSSESGHPVFVSHGLKDQYETTKLHvdvni  676
            DLG+VP  E   KL+NQGMI G S   YR      ++  +V+ +  ++ + + +H     
Sbjct  551  DLGVVPTKEPFQKLFNQGMILGTS---YR-----DSRGALVATDKVEKRDGSFFH-----  597

Query  677  vdndvldvAAFKNWREDFINAEFILEEGKYVCGWEVEKMSKSKFNVVNPDNIVEKYGADT  736
                              +++   LE++         KMSKS  NVVNPD++VE+YGADT
Sbjct  598  ------------------VETGEELEQAP-------AKMSKSLKNVVNPDDVVEQYGADT  632

Query  737  LRMYEMFLGPLTDAKPWNMNGISGTFNFLRKFWRLFFEDQSGKQKWTDAEPTAEELKVLH  796
            LR+YEMF+GPL  + +W+ +G+ G+ +FL +  RL+   +   ++    +      KV +
Sbjct  633  LRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALD------KVYN  686

Query  797  RTIKRVEEDIERLSFNTVVSTFMIAVNDLSDLKCHKKAILQDMLILLAPYAPHITEELWV  856
             T+K V E+++++ FNT ++ +M+ VN  +          ++ + L+AP+APH+ EELW 
Sbjct  687  ETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQ  746

Query  857  ALSNEAGTVSTASFPVFNPKYLEESSFEYPIQINGKVRANIPFPIDMSKEDIEQGVLANE  916
            AL+  + ++S  + P ++   L E+  E  +QI+GKV+A++  + D+S+E++++  LANE
Sbjct  747  ALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQEVALANE  806

Query  917  TVQRWLEGKE  926
             VQ  + GK+
Sbjct  807  KVQAEIAGKD  816


 Score =  183 bits (680),  Expect = 4e-47, Method: Compositional matrix adjust.
 Identities = 93/142 (66%), Positives = 118/142 (84%), Gaps = 0/142 (0%)

Query  3    YNHREIEKKWQQFWEENQIYKTDIDHNKPKYYVLDMFPYPSGAGLHVGHPLGYIASDIIS  62
            Y+H  IE KWQ FW +N+ +KT+ D +KPK+Y LDMFPYPSGAGLHVGHP GY A+DI+S
Sbjct  4    YDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILS  63

Query  63   RYKRLKGFNVLHPMGFDSFGLPAEQYAIQTGQHPAITTEQNISTFIGQMKNIGFSYDWSR  122
            R+KR +G NVLHPMG D+FGLPAEQYA++TG++PA  T +NI+ F  Q++ +GFSYDW R
Sbjct  64   RFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDR  123

Query  123  EVRTSDPNYYKWTQWIFMQLFN  144
            EV T+DPNYYKWTQWIF +L++
Sbjct  124  EVNTTDPNYYKWTQWIFTKLYE  145

1807) leuS in NC_013037


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  406 bits (1529),  Expect = 3e-114, Method: Compositional matrix adjust.
 Identities = 304/742 (41%), Positives = 457/742 (62%), Gaps = 81/742 (10%)

Query  206  LTYVADATVNWCPGLGSVLSNDEV-KDGVSERGGFPVIQKLMRQWMMRITAYAQRLIDGL  264
            L+Y A+  VNW   LG+ ++N+EV  DG SERGG+PV++K MRQWM++ITAYA+RL+++L
Sbjct  148  LAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDL  207

Query  265  DTVDWTESLKEQQRNWIGRSVGALVKFQVWEEREDGGKGESGIVNSLSSFPPSIEVFTTR  324
            + VDW ES+K+ QRNWIG+S GA V F+V     D +K+              + VFTTR
Sbjct  208  EEVDWPESIKDMQRNWIGKSTGANVTFKV----KDTDKD--------------FTVFTTR  249

Query  325  VDTIYGVTFMVIAPEHELVDVITTPEQRAEIDDYIAMTQKKSERDRMSDVKTVSGAFTGA  384
             DT++G T+ V+APEH LVD ITT++Q   + DY   +  KS+  R    K  +G  TG+
Sbjct  250  PDTLFGATYAVLAPEHALVDAITTSDQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGS  309

Query  385  YVLNPFSGEKVPVYIADYVLAGYGTGAVMAVPSGDQRDWNFAKHFNLPIIPILDAQKDIE  444
            Y +NP +G  +PV IADYVLA+YGTGA+MAVP+ D+RDW+FAK+FNL IIP+L++ +   
Sbjct  310  YAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGN--V  367

Query  445  TQADATKEGKYINSGIIDGLTYKEATEKLINVLEEKGLGKGKINYRLRDAVFSRQRYWGE  504
             +A  T +G  INS+++DGL    A  K+++ LE  G+G+ ++ YRLRD +FSRQRYWGE
Sbjct  368  EEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGE  427

Query  505  PVPVYYKNDSEGQPVPYlldlnelplnlpevdKYLPTENGEPPLGRAVgwsygsgvgyns  564
            P+P+   +D+ + +VP     +ELPL LP      P+  GE+PL+               
Sbjct  428  PIPIIHWEDGTSTAVP----ESELPLVLPVTKDIRPSGTGESPLANVT-----------D  472

Query  565  gsghgyETGAGYSYELSTMPGWAGSSWYWYRYMDPKNENEFASKEAIGYWKDVDLYIGGT  624
                  E G     E +TMP WAGSSWY  RY+DP N + +A  E +  W  VD+Y+GG+
Sbjct  473  WLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGA  532

Query  625  EHATGHLLYSRFWNKFMKDRGFVQEEEPFKKLINQGMIQGRSNFVYRVKGEDYSKPVFVS  684
            EHA  HLLY+RFW+K + D G V   EPF+KL+NQGMI G S   YR      S+  +V+
Sbjct  533  EHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTS---YRD-----SRGALVA  584

Query  685  AGLKSQYEVSALHVDVNIVENDVLDVDKFKATRPDIAGEHAEFILEDGKYICGVEVEKMS  744
            ++   + + S +HV+                     +GE+    LE++         KMS
Sbjct  585  TDKVEKRDGSFFHVE---------------------TGEE----LEQAP-------AKMS  612

Query  745  KSKFNVVNPDDIVERYGADTLRLYEMFLGPLDQAKPWNTNGIDGTYRFIRKLWRLFYTET  804
            KS  NVVNPDD+VE+YGADTLR+YEMF+GPLD + +W+ +G++G+ +F+ ++ RL+ T  
Sbjct  613  KSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTK-  671

Query  805  GQWQVKDVPAKPDELKTLHKTIKKIGEDIENFSFNTAVSAFMVCVNELGSQKCQSKEVLQ  864
               ++ +  + + + K  + T+K + E++++  FNTA++ +MV VN    +     +  +
Sbjct  672  ---EITEENSGALD-KVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAK  727

Query  865  QLVILLSPYAPHISEELWTALGNEAGGVSKAEFPVFEAKYVQDSVFEYPVQINGKVRASL  924
             +V L++P+APH++EELW AL   + ++S    P ++   + ++  E  VQI+GKV+A L
Sbjct  728  GFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKL  787

Query  925  TFPLDTPAADIEKEVLADVTVQ  946
              + D +  +++   LA+  VQ
Sbjct  788  VVAKDLSREELQEVALANEKVQ  809


 Score =  176 bits (651),  Expect = 8e-45, Method: Compositional matrix adjust.
 Identities = 90/145 (63%), Positives = 114/145 (79%), Gaps = 0/145 (0%)

Query  1    MSEYSHREIEKKWQDFWQKNGTFSVSNESELPKYYVLDMFPYPSGAGLHVGHPLGYIASD  60
            M+ Y H  IE KWQ FW  N TF  + ++  PK+Y LDMFPYPSGAGLHVGHP GY A+D
Sbjct  1    MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATD  60

Query  61   IYSRYKRLKGFNVLHPMGFDSFGLPAEQYAIQTGQHPAITTEQNISRYIEQLKNLGLSYD  120
            I SR+KR +G NVLHPMG D+FGLPAEQYA++TG++PA  T +NI+ +  Q++ LG+SYD
Sbjct  61   ILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYD  120

Query  121  WNREVRTSDPGYYKWTQWIFSELFN  145
            W+REV T+DP YYKWTQWIF+ L++
Sbjct  121  WDREVNTTDPNYYKWTQWIFTKLYE  145

1808) leuS in NC_017376


> NC_007297_P1|12|G12|161936127|YP_281511.2|Streptococcus_pyogenes_MGAS5005|+|11319..13820|leuS|M5005_Spy_0147|leucyl-tRNA 
synthetase
Length=833

 Score =  386 bits (1453),  Expect = 3e-108, Method: Compositional matrix adjust.
 Identities = 273/676 (41%), Positives = 407/676 (61%), Gaps = 65/676 (9%)

Query  2    DFMSIEKKWQEFWWKNKSFEPKDDFNLPKKYILSMLPYPSGE-IHMGHVRNYTIGDALAR  60
            D  +IE KWQ FW  N +F    D + PK Y L M+PYPSG  +H+GH   YT  D L+R
Sbjct  5    DHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSR  64

Query  61   YYRLHHYNVLHPMGFDSFGMPAENAAIKHGIHPKTWTYENIENMQKEFEALGFSFSKNRE  120
            + R +  NVLHPMG D+FG+PAE+ A+  G +P   T ENI N +++++ALGFS+  +RE
Sbjct  65   FKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDRE  124

Query  121  FATSDPDYTKFEQQFFIDLWEKGLVYRKKAMLNWCPNDKTVLANEQVI-DGRCWRCDTEV  179
              T+DP+Y K  Q +F  L EKGL Y     +NW  +  T +ANE+V+ DG   R +  V
Sbjct  125  VNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPV  184

Query  180  IQKELYQYYLKITNYAEELLKDLETLENHWPSQVLIMQKNWIGKSSGLQFGFKIADECLK  239
            ++K + Q  LKIT YAE LL DLE ++  WP  +  MQ+NWIGKS+G +  FK+ D    
Sbjct  185  VRKPMRQWMLKITAYAERLLEDLEEVD--WPESIKDMQRNWIGKSTGANVTFKVKD----  238

Query  240  ACNGIQEIEVFTTRADTIYGVTYIAIAPEHPLVEHAIKQVSQEDS-------KMIKAILN  292
                 +++ VFTTR+DT++G TY  +APEH+LV+ AI    Q ++         +K+ L 
Sbjct  239  ---TDKDFTVFTTRPDTLFGATYAVLAPEHALVD-AITTSDQAEAVADYKRQASLKSDLA  294

Query  293  TTQRERALEKKGAFLGIYAIHPLTKQKIPVWVANFALANYGSGALMGVPACDERDFEFAN  352
             T+  +  EK G   G YAI+P+  + +PVW+A++ LA+YG+GA+M+VPA DERD EFA+
Sbjct  295  RTDLAK--EKTGVWTGSYAINPVNGKEMPVWIADYVLASYGTGAIMAVPAHDERDWEFAK  352

Query  353  LYHIPIKVITQSPQNLPHT-KEEVLKNSGEW-SDLSSSVAREKIIVYFEKENLGKRVINY  410
             +++ I  + ++ +    +  E+ L  +++   +L  + A  K++  +E E +G+  + Y
Sbjct  353  QFNLDIIPVLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNENVTY  412

Query  411  RLQDWGVSRQRYWGAPIPMIH--CKHCGIVPETQLPVTLP--EDIVIDGEGN-PLEKHAS  465
            RL+DW  SRQRYWG PIP+IH        VPE++LP+ LP   DI   G G+ PL + + 
Sbjct  413  RLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTD  472

Query  466  WKFAQCPKCHKNALRETDTMDTFIQSSWYFLRYTTPQNQRENQAFDQNYLKYFMPVDTYI  525
            W +        ++ RET+TM     SSWY+LRY  P+N   ++  D++ LK  +PVD Y+
Sbjct  473  W-LEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHN--TEKLADEELLKQWLPVDIYV  529

Query  526  GGIEHAILHLLYARFFTKALRDLGYLHLDEPFKQLITQGMVL------------------  567
            GG EHA+LHLLYARF  K L DLG +   EPF++L+ QGM+L                  
Sbjct  530  GGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVE  589

Query  568  -KDGT---------------KMSKSKGNVVSPKEILKKYGADAARLFILFAAPPAKELEW  611
             +DG+               KMSKS  NVV+P +++ +YGAD+ R++ +F +P    + W
Sbjct  590  KRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAW  649

Query  612  NDSALEGAHRFIKRLY  627
            ++ +LEG+++F+ R+Y
Sbjct  650  SEEGLEGSRKFLDRVY  665