Homologs of dfrA12 gene of EU780013

Hit (GenBank Accn)	Product	Source Genome	Eval.	Ident.(%)
1) A225_R1p0770   ( YP_006501616.1 )	Dihydrofolate reductase	NC_018107 (Klebsiella oxytoca E718)	3e-75	100
2) N559_5185   ( YP_008414966.1 )	dihydrofolate reductase	NC_022078 (Klebsiella pneumoniae JM45)	3e-75	100
3) tri   ( YP_209335.1 )	dihydrofolate reductase	NC_006856 (Salmonella enterica SC-B67)	3e-75	100
4) STMDT12_L00660   ( YP_005250485.1 )	dihydrofolate reductase	NC_016861 (Salmonella enterica T000240)	3e-75	100
5) STU288_1p00755   ( YP_007905885.1 )	dihydrofolate reductase	NC_021155 (Salmonella enterica U288)	3e-75	100
6) KPHS_p300720   ( YP_005221020.1 )	dihydrofolate reductase	NC_016839 (Klebsiella pneumoniae HS11286)	9e-63	98
7) Hneap_1653   ( YP_003263526.1 )	dihydrofolate reductase	NC_013422 (Halothiobacillus neapolitanus c2)	3e-60	80
8) MCCL_plsB0051   ( YP_002559382.1 )	hypothetical protein	NC_011996 (Macrococcus caseolyticus JCSC5402)	2e-36	48
9) Gura_0932   ( YP_001229711.1 )	dihydrofolate reductase	NC_009483 (Geobacter uraniireducens Rf4)	5e-35	47
10) Geob_1750   ( YP_002537209.1 )	dihydrofolate reductase	NC_011979 (Geobacter daltonii FRC-32)	2e-33	47
11) Clocel_0240   ( YP_003841788.1 )	dihydrofolate reductase subunit	NC_014393 (Clostridium cellulovorans 743B)	1e-31	42
12) Fjoh_1468   ( YP_001193819.1 )	dihydrofolate reductase	NC_009441 (Flavobacterium johnsoniae UW101)	9e-32	42
13) SSUBM407_0957   ( YP_003028702.1 )	dihydrofolate reductase	NC_012926 (Streptococcus suis BM407)	2e-31	42
14) Mar181_0627   ( YP_004480603.1 )	dihydrofolate reductase	NC_015559 (Marinomonas posidonica IVIA-Po-181)	8e-31	45
15) Mmwyl1_3741   ( YP_001342577.1 )	dihydrofolate reductase	NC_009654 (Marinomonas sp. MWYL1)	4e-30	45
16) dfrA   ( NP_244317.1 )	dihydrofolate reductase	NC_002570 (Bacillus halodurans C-125)	4e-30	42
17) dfrD_2   ( YP_008395020.1 )	dihydrofolate reductase, DfrD_2	NC_021994 (Enterococcus faecium AUS0085)	8e-30	43
18) Marme_0712   ( YP_004311831.1 )	dihydrofolate reductase	NC_015276 (Marinomonas mediterranea MMB-1)	1e-29	42
19) Slin_1051   ( YP_003385901.1 )	Dihydrofolate reductase	NC_013730 (Spirosoma linguale DSM 74)	4e-29	45
20) Weevi_0641   ( YP_004237936.1 )	dihydrofolate reductase	NC_015144 (Weeksella virosa DSM 16922)	4e-29	44
21) STH3116   ( YP_076942.1 )	dihydrofolate reductase	NC_006177 (Symbiobacterium thermophilum IAM 14863)	5e-29	46
22) Oweho_2962   ( YP_004990564.1 )	dihydrofolate reductase	NC_016599 (Owenweeksia hongkongensis DSM 17368)	1e-28	42
23) Tbd_2039   ( YP_315797.1 )	dihydrofolate reductase	NC_007404 (Thiobacillus denitrificans ATCC 25259)	1e-28	41
24) Pjdr2_2656   ( YP_003011396.1 )	dihydrofolate reductase	NC_012914 (Paenibacillus sp. JDR-2)	2e-28	46
25) EUBELI_01781   ( YP_002931218.1 )	dihydrofolate reductase	NC_012778 (Eubacterium eligens ATCC 27750)	2e-28	43
26) B565_0876   ( YP_004391528.1 )	dihydrofolate reductase type 3	NC_015424 (Aeromonas veronii B565)	2e-28	42
27) Lcho_1259   ( YP_001790293.1 )	dihydrofolate reductase	NC_010524 (Leptothrix cholodnii SP-6)	2e-28	42
28) folA   ( YP_006819097.1 )	protein containing dihydrofolate reductase region domain	NC_018691 (Alcanivorax dieselolei B5)	2e-28	41
29) folA   ( YP_694063.1 )	dihydrofolate reductase	NC_008260 (Alcanivorax borkumensis SK2)	3e-28	41
30) folA   ( YP_006721905.1 )	dihydrofolate reductase	NC_007517 (Geobacter metallireducens GS-15)	4e-28	42
31) folA   ( YP_001140814.1 )	dihydrofolate reductase	NC_009348 (Aeromonas salmonicida A449)	1e-27	42
32) Phep_1421   ( YP_003091697.1 )	dihydrofolate reductase	NC_013061 (Pedobacter heparinus DSM 2366)	2e-27	41
33) TKWG_20480   ( YP_006380827.1 )	hypothetical protein	NC_017964 (Advenella kashmirensis WT001)	2e-27	44
34) Krodi_0787   ( YP_004430039.1 )	dihydrofolate reductase subunit	NC_015496 (Krokinobacter sp. 4H-3-7-5)	2e-27	44
35) Metme_4551   ( YP_004515389.1 )	Dihydrofolate reductase	NC_015572 (Methylomonas methanica MC09)	3e-27	41
36) folA   ( YP_785039.1 )	dihydrofolate reductase	NC_010645 (Bordetella avium 197N)	4e-27	42
37) dfrA   ( YP_005493359.1 )	dihydrofolate reductase subunit	NC_017138 (Bacillus megaterium WSH-002)	4e-27	41
38) Swoo_1009   ( YP_001759397.1 )	dihydrofolate reductase	NC_010506 (Shewanella woodyi ATCC 51908)	4e-27	41
39) Theco_1713   ( YP_007212843.1 )	dihydrofolate reductase	NC_019897 (Thermobacillus composti KWC4)	5e-27	46
40) Runsl_2666   ( YP_004656198.1 )	dihydrofolate reductase	NC_015703 (Runella slithyformis DSM 19594)	6e-27	46
41) M5M_13555   ( YP_006917581.1 )	dihydrofolate reductase	NC_018868 (Simiduia agarivorans SA1)	6e-27	43
42) folA   ( YP_003981636.1 )	dihydrofolate reductase	NC_014640 (Achromobacter xylosoxidans A8)	6e-27	42
43) Ccel_1310   ( YP_002505644.1 )	dihydrofolate reductase subunit	NC_011898 (Clostridium cellulolyticum H10)	6e-27	41
44) TOL_3595   ( YP_007684216.1 )	dihydrofolate reductase	NC_020888 (Thalassolituus oleivorans MIL-1)	1e-26	43
45) folA   ( YP_857866.1 )	dihydrofolate reductase	NC_008570 (Aeromonas hydrophila ATCC 7966)	2e-26	43
46) folA   ( YP_005082760.1 )	Dihydrofolate reductase type III DHFR	NC_016642 (Pseudovibrio sp. FO-BEG1)	3e-26	42
47) AHML_18030   ( YP_008044719.1 )	dihydrofolate reductase	NC_021290 (Aeromonas hydrophila ML09-119)	3e-26	43
48) Tgr7_2748   ( YP_002514809.1 )	dihydrofolate reductase	NC_011901 (Thioalkalivibrio sulfidophilus HL-EbGR7)	4e-26	41
49) Noca_2312   ( YP_923504.1 )	dihydrofolate reductase	NC_008699 (Nocardioides sp. JS614)	6e-26	48
50) Ssed_0959   ( YP_001472698.1 )	dihydrofolate reductase	NC_009831 (Shewanella sediminis HAW-EB3)	1e-25	45
51) SCD_n01866   ( YP_008546709.1 )	dihydrofolate reductase	NC_022357 (Sulfuricella denitrificans skB26)	1e-25	43
52) Tola_2373   ( YP_002893556.1 )	Dihydrofolate reductase	NC_012691 (Tolumonas auensis DSM 9187)	7e-26	42
53) folA   ( YP_001632651.1 )	hypothetical protein	NC_010170 (Bordetella petrii DSM 12804)	8e-26	44
54) Mnod_0700   ( YP_002496035.1 )	dihydrofolate reductase subunit	NC_011894 (Methylobacterium nodulans ORS 2060)	2e-25	42
55) Shew185_1041   ( YP_001365256.1 )	dihydrofolate reductase	NC_009665 (Shewanella baltica OS185)	2e-25	42
56) Sbal195_1074   ( YP_001553510.1 )	dihydrofolate reductase	NC_009997 (Shewanella baltica OS195)	2e-25	42
57) Sbal678_1101   ( YP_005272331.1 )	Dihydrofolate reductase	NC_016901 (Shewanella baltica OS678)	2e-25	42
58) NH44784_029401   ( YP_008030023.1 )	Dihydrofolate reductase	NC_021285 (Achromobacter xylosoxidans NH44784-1996)	3e-25	49
59) folA   ( YP_002304388.1 )	dihydrofolate reductase	NC_011527 (Coxiella burnetii CbuG_Q212)	3e-25	44
60) folA   ( YP_002306287.1 )	dihydrofolate reductase	NC_011528 (Coxiella burnetii CbuK_Q154)	3e-25	44
61) folA   ( YP_001425396.1 )	dihydrofolate reductase	NC_009727 (Coxiella burnetii Dugway 5J108-111)	3e-25	44
62) folA   ( YP_001595986.1 )	dihydrofolate reductase	NC_010117 (Coxiella burnetii RSA 331)	3e-25	44
63) folA   ( NP_820968.1 )	dihydrofolate reductase	NC_002971 (Coxiella burnetii RSA 493)	3e-25	44
64) folA   ( YP_005428721.1 )	dihydrofolate reductase	NC_017067 (Marinobacter hydrocarbonoclasticus ATCC 49840)	3e-25	42
65) Kfla_5968   ( YP_003383770.1 )	dihydrofolate reductase	NC_013729 (Kribbella flavida DSM 17836)	3e-25	41
66) Shal_0910   ( YP_001673144.1 )	dihydrofolate reductase	NC_010334 (Shewanella halifaxensis HAW-EB4)	4e-25	42
67) Shew_0874   ( YP_001093005.1 )	dihydrofolate reductase	NC_009092 (Shewanella loihica PV-4)	4e-25	42
68) UMN179_01397   ( YP_004420313.1 )	dihydrofolate reductase	NC_015460 (Gallibacterium anatis UMN179)	5e-25	45
69) Maqu_2431   ( YP_959693.1 )	dihydrofolate reductase	NC_008740 (Marinobacter aquaeolei VT8)	5e-25	41
70) Sama_2824   ( YP_928696.1 )	dihydrofolate reductase	NC_008700 (Shewanella amazonensis SB2B)	8e-25	45
71) M446_1090   ( YP_001768052.1 )	dihydrofolate reductase	NC_010511 (Methylobacterium sp. 4-46)	8e-25	43
72) Sden_2922   ( YP_563923.1 )	dihydrofolate reductase	NC_007954 (Shewanella denitrificans OS217)	8e-25	41
73) Alvin_2149   ( YP_003444102.1 )	dihydrofolate reductase	NC_013851 (Allochromatium vinosum DSM 180)	9e-25	46
74) Emtol_1434   ( YP_006872607.1 )	dihydrofolate reductase region	NC_018748 (Emticicia oligotrophica DSM 17448)	1e-24	43
75) Lbys_2007   ( YP_003998056.1 )	dihydrofolate reductase	NC_014655 (Leadbetterella byssophila DSM 17132)	1e-24	43
76) HP15_587   ( YP_005884279.1 )	hypothetical protein	NC_017506 (Marinobacter adhaerens HP15)	1e-24	43
77) Hneap_0899   ( YP_003262789.1 )	dihydrofolate reductase	NC_013422 (Halothiobacillus neapolitanus c2)	1e-24	41
78) dfrA   ( YP_005356523.1 )	Dihydrofolate reductase	NC_017025 (Flavobacterium indicum GPTSA100-9)	2e-24	46
79) folA   ( NP_719188.1 )	dihydrofolate reductase FolA	NC_004347 (Shewanella oneidensis MR-1)	2e-24	42
80) Mpop_2781   ( YP_001925471.1 )	dihydrofolate reductase	NC_010725 (Methylobacterium populi BJ001)	3e-24	45
81) Aave_1448   ( YP_969813.1 )	dihydrofolate reductase	NC_008752 (Acidovorax citrulli AAC00-1)	4e-24	42
82) FCOL_04070   ( YP_004941441.1 )	dihydrofolate reductase	NC_016510 (Flavobacterium columnare ATCC 49512)	5e-24	43
83) Acav_1487   ( YP_004233976.1 )	dihydrofolate reductase	NC_015138 (Acidovorax avenae ATCC 19860)	9e-24	42
84) dfrA   ( YP_001295259.1 )	Dihydrofolate reductase	NC_009613 (Flavobacterium psychrophilum JIP02/86)	9e-24	41
85) Aeqsu_0718   ( YP_006417241.1 )	dihydrofolate reductase	NC_018013 (Aequorivita sublithincola DSM 14238)	1e-23	41
86) Mlg_0423   ( YP_741267.1 )	dihydrofolate reductase	NC_008340 (Alkalilimnicola ehrlichii MLHE-1)	1e-23	41
87) folA   ( YP_001980992.1 )	dihydrofolate reductase	NC_010995 (Cellvibrio japonicus Ueda107)	1e-23	41
88) Clole_0608   ( YP_004307540.1 )	dihydrofolate reductase	NC_015275 (Clostridium lentocellum DSM 5427)	1e-23	41
89) Spea_0857   ( YP_001500719.1 )	dihydrofolate reductase	NC_009901 (Shewanella pealeana ATCC 700345)	2e-23	42
90) H045_19415   ( YP_007399441.1 )	dihydrofolate reductase	NC_020209 (Pseudomonas poae RE*1-1-14)	2e-23	41
91) G432_09820   ( YP_007616285.1 )	dihydrofolate reductase	NC_020561 (Sphingomonas sp. MM-1)	2e-23	45
92) PPE_02527   ( YP_003870895.1 )	dihydrofolate reductase	NC_014483 (Paenibacillus polymyxa E681)	2e-23	43
93) PB2503_08189   ( YP_003854835.1 )	dihydrofolate reductase FolA	NC_014414 (Parvularcula bermudensis HTCC2503)	2e-23	42
94) Psefu_4265   ( YP_004476311.1 )	Dihydrofolate reductase	NC_015556 (Pseudomonas fulva 12-X)	4e-23	42
95) dfrA   ( YP_002787091.1 )	dihydrofolate reductase	NC_012526 (Deinococcus deserti VCD115)	4e-23	41
96) folA   ( NP_887420.1 )	dihydrofolate reductase	NC_002927 (Bordetella bronchiseptica RB50)	5e-23	42
97) LHK_00787   ( YP_002794789.1 )	Dihydrofolate reductase	NC_012559 (Laribacter hongkongensis HLHK9)	5e-23	42
98) folA   ( YP_003465092.1 )	hypothetical protein	NC_013891 (Listeria seeligeri SLCC3954)	5e-23	41
99) folA   ( YP_005177290.1 )	dihydrofolate reductase	NC_016808 (Pasteurella multocida 36950)	6e-23	44
100) RPD_3353   ( YP_570478.1 )	dihydrofolate reductase	NC_007958 (Rhodopseudomonas palustris BisB5)	6e-23	41
101) Coch_0487   ( YP_003140611.1 )	Dihydrofolate reductase	NC_013162 (Capnocytophaga ochracea DSM 7271)	8e-23	48
102) dfrA   ( YP_004735333.1 )	dihydrofolate reductase	NC_015844 (Zobellia galactanivorans DsiJT)	1e-22	45
103) NT08PM_1502   ( YP_006240377.1 )	dihydrofolate reductase	NC_017764 (Pasteurella multocida 3480)	1e-22	43
104) folA   ( YP_005363879.1 )	dihydrofolate reductase	NC_017027 (Pasteurella multocida HN06)	1e-22	43
105) folA   ( NP_246832.1 )	hypothetical protein	NC_002663 (Pasteurella multocida Pm70)	1e-22	43
106) Sput200_0983   ( YP_006008924.1 )	Dihydrofolate reductase	NC_017566 (Shewanella putrefaciens 200)	1e-22	43
107) folA   ( YP_002897706.1 )	dihydrofolate reductase	NC_012695 (Burkholderia pseudomallei MSHR346)	1e-22	43
108) folA   ( YP_006894835.1 )	dihydrofolate reductase	NC_018828 (Bordetella parapertussis Bpp5)	1e-22	42
109) Mrad2831_4526   ( YP_001757175.1 )	dihydrofolate reductase	NC_010505 (Methylobacterium radiotolerans JCM 2831)	2e-22	46
110) Snov_3092   ( YP_003694986.1 )	dihydrofolate reductase	NC_014217 (Starkeya novella DSM 506)	2e-22	46
111) folA   ( YP_001345838.1 )	dihydrofolate reductase	NC_009656 (Pseudomonas aeruginosa PA7)	2e-22	42
112) P700755_003057   ( YP_006868477.1 )	dihydrofolate reductase FolA	NC_018721 (Psychroflexus torquis ATCC 700755)	3e-22	43
113) CGSHiEE_07515   ( YP_001291209.1 )	dihydrofolate reductase	NC_009566 (Haemophilus influenzae PittEE)	3e-22	41
114) K734_02390   ( YP_008033979.1 )	dihydrofolate reductase	NC_021286 (Idiomarina loihiensis GSL 199)	3e-22	43
115) folA   ( YP_154870.1 )	dihydrofolate reductase	NC_006512 (Idiomarina loihiensis L2TR)	3e-22	43
116) Nham_2729   ( YP_577968.1 )	dihydrofolate reductase	NC_007964 (Nitrobacter hamburgensis X14)	3e-22	41
117) Ping_1045   ( YP_942483.1 )	dihydrofolate reductase	NC_008709 (Psychromonas ingrahamii 37)	5e-22	42
118) Rpdx1_1866   ( YP_004108211.1 )	dihydrofolate reductase	NC_014834 (Rhodopseudomonas palustris DX-1)	5e-22	42
119) Sbal175_3293   ( YP_006021834.1 )	Dihydrofolate reductase	NC_017571 (Shewanella baltica BA175)	5e-22	42
120) Sbal223_3318   ( YP_002359225.1 )	dihydrofolate reductase	NC_011663 (Shewanella baltica OS223)	5e-22	42
121) Dfer_4811   ( YP_003089177.1 )	dihydrofolate reductase	NC_013037 (Dyadobacter fermentans DSM 18053)	5e-22	41
122) folA   ( NP_883118.1 )	dihydrofolate reductase	NC_002928 (Bordetella parapertussis 12822)	7e-22	42
123) folA   ( YP_006889590.1 )	dihydrofolate reductase	NC_017454 (Geobacter sulfurreducens KN400)	7e-22	42
124) Sputcn32_0984   ( YP_001182512.1 )	dihydrofolate reductase	NC_009438 (Shewanella putrefaciens CN-32)	1e-21	43
125) Sputw3181_3183   ( YP_964552.1 )	dihydrofolate reductase	NC_008750 (Shewanella sp. W3-18-1)	1e-21	43
126) folA   ( NP_951629.1 )	dihydrofolate reductase	NC_002939 (Geobacter sulfurreducens PCA)	1e-21	42
127) folA   ( YP_002924386.1 )	dihydrofolate reductase type I, trimethoprim resistance	NC_012751 (Candidatus Hamiltonella defensa T5A)	1e-21	41
128) PSEBR_a5358   ( YP_004356865.1 )	dihydrofolate reductase	NC_015379 (Pseudomonas brassicacearum NFM421)	1e-21	41
129) Celf_1550   ( YP_004453071.1 )	dihydrofolate reductase region	NC_015514 (Cellulomonas fimi ATCC 484)	1e-21	43
130) folA   ( YP_006899085.1 )	dihydrofolate reductase	NC_018829 (Bordetella bronchiseptica MO149)	1e-21	42
131) folA   ( YP_006627328.1 )	dihydrofolate reductase	NC_018518 (Bordetella pertussis 18323)	1e-21	42
132) folA   ( YP_005591118.1 )	dihydrofolate reductase	NC_017223 (Bordetella pertussis CS)	1e-21	42
133) folA   ( NP_881720.1 )	dihydrofolate reductase	NC_002929 (Bordetella pertussis Tohama I)	1e-21	42
134) folA   ( YP_006968624.1 )	dihydrofolate reductase	NC_019382 (Bordetella bronchiseptica 253)	2e-21	42
135) Sbal117_1071   ( YP_006036342.1 )	Dihydrofolate reductase	NC_017579 (Shewanella baltica OS117)	2e-21	41
136) Sbal_0972   ( YP_001049365.1 )	dihydrofolate reductase	NC_009052 (Shewanella baltica OS155)	2e-21	41
137) Mext_2659   ( YP_001640122.1 )	dihydrofolate reductase	NC_010172 (Methylobacterium extorquens PA1)	2e-21	48
138) Mchl_2886   ( YP_002421653.1 )	dihydrofolate reductase	NC_011757 (Methylobacterium chloromethanicum CM4)	2e-21	47
139) Varpa_1813   ( YP_004154134.1 )	dihydrofolate reductase region	NC_014931 (Variovorax paradoxus EPS)	2e-21	41
140) dfrA   ( YP_002963882.1 )	dihydrofolate reductase	NC_012808 (Methylobacterium extorquens AM1)	3e-21	47
141) Celal_2140   ( YP_004164933.1 )	dihydrofolate reductase	NC_014934 (Cellulophaga algicola DSM 14237)	3e-21	42
142) dfrA [H]   ( YP_007216239.1 )	Dihydrofolate reductase	NC_019902 (Thioalkalivibrio nitratireducens DSM 14787)	3e-21	42
143) C380_08895   ( YP_006854119.1 )	dihydrofolate reductase	NC_018708 (Acidovorax sp. KKS102)	3e-21	42
144) dfrA   ( YP_003068918.1 )	dihydrofolate reductase	NC_012988 (Methylobacterium extorquens DM4)	4e-21	47
145) Mesil_0096   ( YP_003683549.1 )	dihydrofolate reductase	NC_014212 (Meiothermus silvanus DSM 9946)	7e-21	44
146) folA   ( YP_001906665.1 )	dihydrofolate reductase	NC_010694 (Erwinia tasmaniensis Et1/99)	7e-21	43
147) Echvi_2448   ( YP_007224705.1 )	dihydrofolate reductase	NC_019904 (Echinicola vietnamensis DSM 17526)	7e-21	42
148) PputUW4_05157   ( YP_007032152.1 )	dihydrofolate reductase	NC_019670 (Pseudomonas sp. UW4)	7e-21	42
149) folA   ( YP_005951693.1 )	dihydrofolate reductase FolA	NC_017538 (Oligotropha carboxidovorans OM4)	1e-20	41
150) folA   ( YP_004633630.1 )	dihydrofolate reductase FolA	NC_015684 (Oligotropha carboxidovorans OM5)	1e-20	41
151) folA   ( YP_002288274.1 )	dihydrofolate reductase	NC_011386 (Oligotropha carboxidovorans OM5; ATCC 49405)	1e-20	41
152) folA   ( YP_934700.1 )	FolA protein	NC_008702 (Azoarcus sp. BH72)	1e-20	41
153) folA   ( YP_003537753.1 )	dihydrofolate reductase	NC_013971 (Erwinia amylovora ATCC 49946)	1e-20	42
154) Sde_0351   ( YP_525827.1 )	dihydrofolate reductase	NC_007912 (Saccharophagus degradans 2-40)	2e-20	41
155) dhfrIII   ( YP_006557144.1 )	dihydrofolate reductase type 3	NC_018268 (Marinobacter sp. BSs20148)	2e-20	41
156) folA   ( YP_002647738.1 )	dihydrofolate reductase	NC_012214 (Erwinia pyrifoliae Ep1/96)	2e-20	43
157) Caka_1328   ( YP_003548518.1 )	dihydrofolate reductase	NC_014008 (Coraliomargarita akajimensis DSM 45221)	2e-20	42
158) NGO1694   ( YP_208730.1 )	hypothetical protein	NC_002946 (Neisseria gonorrhoeae FA 1090)	2e-20	45
159) folA   ( YP_003532284.1 )	dihydrofolate reductase	NC_013961 (Erwinia amylovora CFBP1430)	2e-20	42
160) folA   ( YP_005801502.1 )	protein folA	NC_017390 (Erwinia pyrifoliae DSM 12163)	2e-20	42
161) ambt_15520   ( YP_004468416.1 )	dihydrofolate reductase type I	NC_015554 (Alteromonas sp. SN2)	3e-20	42
162) folA   ( YP_005816954.1 )	hypothetical protein	NC_017445 (Erwinia sp. Ejp617)	4e-20	43
163) Shewmr7_3120   ( YP_739161.1 )	dihydrofolate reductase	NC_008322 (Shewanella sp. MR-7)	4e-20	42
164) RPE_2177   ( YP_781101.1 )	dihydrofolate reductase	NC_008435 (Rhodopseudomonas palustris BisA53)	5e-20	41
165) folA   ( YP_001476954.1 )	dihydrofolate reductase	NC_009832 (Serratia proteamaculans 568)	5e-20	41
166) SPISAL_08210   ( YP_008047201.1 )	dihydrofolate reductase	NC_021291 (Spiribacter salinus M19-40)	5e-20	41
167) folA   ( YP_759193.1 )	dihydrofolate reductase	NC_008358 (Hyphomonas neptunium ATCC 15444)	6e-20	41
168) Shewmr4_0900   ( YP_733037.1 )	dihydrofolate reductase	NC_008321 (Shewanella sp. MR-4)	7e-20	42
169) Thivi_0961   ( YP_006413121.1 )	dihydrofolate reductase	NC_018012 (Thiocystis violascens DSM 198)	8e-20	41
170) folA   ( YP_003627640.1 )	dihydrofolate reductase	NC_014147 (Moraxella catarrhalis RH4)	9e-20	41
171) folA   ( YP_003467711.1 )	dihydrofolate reductase type I, trimethoprim resistance	NC_013892 (Xenorhabdus bovienii SS-2004)	1e-19	43
172) Shewana3_3214   ( YP_870844.1 )	dihydrofolate reductase	NC_008577 (Shewanella sp. ANA-3)	1e-19	42
173) folA   ( YP_003740079.1 )	dihydrofolate reductase	NC_014306 (Erwinia billingiae Eb661)	1e-19	41
174) Tmz1t_1591   ( YP_002355245.1 )	dihydrofolate reductase	NC_011662 (Thauera sp. MZ1T)	1e-19	41
175) folA   ( YP_007628070.1 )	dihydrofolate reductase	NC_020796 (Edwardsiella tarda C07-087)	2e-19	41
176) folA   ( YP_003294655.1 )	dihydrofolate reductase	NC_013508 (Edwardsiella tarda EIB202)	2e-19	41
177) ETAF_0543   ( YP_005698159.1 )	Dihydrofolate reductase	NC_017309 (Edwardsiella tarda FL6-60)	2e-19	41
178) PADK2_01755   ( YP_006480348.1 )	dihydrofolate reductase	NC_018080 (Pseudomonas aeruginosa DK2)	2e-19	41
179) amb1326   ( YP_420689.1 )	dihydrofolate reductase	NC_007626 (Magnetospirillum magneticum AMB-1)	3e-19	45
180) G655_01775   ( YP_007707204.1 )	dihydrofolate reductase	NC_020912 (Pseudomonas aeruginosa B136-33)	3e-19	41
181) folA   ( YP_005972939.1 )	dihydrofolate reductase	NC_017548 (Pseudomonas aeruginosa M18)	3e-19	41
182) folA   ( YP_005984048.1 )	dihydrofolate reductase	NC_017549 (Pseudomonas aeruginosa NCGM2.S1)	3e-19	41
183) folA   ( NP_249041.1 )	dihydrofolate reductase	NC_002516 (Pseudomonas aeruginosa PAO1)	3e-19	41
184) M062_01750   ( YP_008130815.1 )	diacylglycerol kinase	NC_021577 (Pseudomonas aeruginosa RP73)	3e-19	41
185) folA   ( YP_788521.1 )	dihydrofolate reductase	NC_008463 (Pseudomonas aeruginosa UCBPP-PA14)	3e-19	41
186) folA   ( YP_061969.1 )	dihydrofolate reductase	NC_006087 (Leifsonia xyli CTCB07)	3e-19	41
187) M943_14275   ( YP_008226858.1 )	dihydrofolate reductase	NC_021740 (Mycobacterium tuberculosis EAI5)	4e-19	41
188) dfrA   ( YP_004724417.1 )	dihydrofolate reductase	NC_015758 (Mycobacterium africanum GM041182)	5e-19	41
189) dfrA   ( NP_856431.1 )	dihydrofolate reductase	NC_002945 (Mycobacterium bovis AF2122/97)	5e-19	41
190) dfrA   ( YP_978866.1 )	dihydrofolate reductase dfrA	NC_008769 (Mycobacterium bovis BCG Pasteur 1173P2)	5e-19	41
191) K60_028580   ( YP_007431916.1 )	dihydrofolate reductase dfrA	NC_020245 (Mycobacterium bovis Korea 1168P)	5e-19	41
192) dfrA   ( YP_005172230.1 )	putative dihydrofolate reductase	NC_016804 (Mycobacterium bovis Mexico)	5e-19	41
193) dfrA   ( YP_002645823.1 )	dihydrofolate reductase	NC_012207 (Mycobacterium bovis Tokyo 172)	5e-19	41
194) dfrA   ( YP_004746217.1 )	dihydrofolate reductase DFRA	NC_015848 (Mycobacterium canettii CIPT 140010059)	5e-19	41
195) dfrA   ( YP_007261509.1 )	Dihydrofolate reductase DfrA (DHFR) (tetrahydrofolate dehydrogenase)	NC_019950 (Mycobacterium canettii CIPT 140060008)	5e-19	41
196) dfrA   ( YP_007288708.1 )	Dihydrofolate reductase DfrA (DHFR) (tetrahydrofolate dehydrogenase)	NC_019965 (Mycobacterium canettii CIPT 140070008)	5e-19	41
197) dfrA   ( YP_007265490.1 )	Dihydrofolate reductase DfrA (DHFR) (tetrahydrofolate dehydrogenase)	NC_019951 (Mycobacterium canettii CIPT 140070010)	5e-19	41
198) dfrA   ( YP_007269450.1 )	Dihydrofolate reductase DfrA (DHFR) (tetrahydrofolate dehydrogenase)	NC_019952 (Mycobacterium canettii CIPT 140070017)	5e-19	41
199) MT7199_2796   ( YP_007352533.1 )	DIHYDROFOLATE REDUCTASE DFRA (DHFR) (TETRAHYDROFOLATE DEHYDROGENASE)	NC_020089 (Mycobacterium tuberculosis 7199-99)	5e-19	41
200) J112_14800   ( YP_007855771.1 )	dihydrofolate reductase	NC_021054 (Mycobacterium tuberculosis Beijing/NITR203)	5e-19	41
201) J113_19165   ( YP_007962638.1 )	dihydrofolate reductase	NC_021193 (Mycobacterium tuberculosis CAS/NITR204)	5e-19	41
202) CCDC5079_2534   ( YP_005913957.1 )	dihydrofolate reductase dfrA (tetrahydrofolate dehydrogenase)	NC_017523 (Mycobacterium tuberculosis CCDC5079)	5e-19	41
203) dfrA   ( YP_008007755.1 )	dihydrofolate reductase	NC_021251 (Mycobacterium tuberculosis CCDC5079)	5e-19	41
204) CCDC5180_2504   ( YP_005910336.1 )	dihydrofolate reductase dfrA (tetrahydrofolate dehydrogenase)	NC_017522 (Mycobacterium tuberculosis CCDC5180)	5e-19	41
205) folA   ( NP_337338.1 )	dihydrofolate reductase	NC_002755 (Mycobacterium tuberculosis CDC1551)	5e-19	41
206) dfrA   ( YP_005917843.1 )	dihydrofolate reductase DFRA (DHFR) (tetrahydrofolate dehydrogenase)	NC_017524 (Mycobacterium tuberculosis CTRI-2)	5e-19	41
207) J114_14740   ( YP_007966679.1 )	dihydrofolate reductase	NC_021194 (Mycobacterium tuberculosis EAI5/NITR206)	5e-19	41
208) dfrA   ( YP_007611485.1 )	dihydrofolate reductase	NC_020559 (Mycobacterium tuberculosis Erdman (ATCC35801))	5e-19	41
209) TBFG_12776   ( YP_001288705.1 )	dihydrofolate reductase dfrA (tetrahydrofolate dehydrogenase)	NC_009565 (Mycobacterium tuberculosis F11)	5e-19	41
210) dfrA   ( YP_001284128.1 )	dihydrofolate reductase	NC_009525 (Mycobacterium tuberculosis H37Ra)	5e-19	41
211) dfrA   ( NP_217279.1 )	Dihydrofolate reductase DfrA (DHFR) (tetrahydrofolate dehydrogenase)	NC_000962 (Mycobacterium tuberculosis H37Rv)	5e-19	41
212) RVBD_2763c   ( YP_006516208.1 )	dihydrofolate reductase	NC_018143 (Mycobacterium tuberculosis H37Rv)	5e-19	41
213) TBHG_02695   ( YP_002159720.2 )	dihydrofolate reductase DfrA	NC_022350 (Mycobacterium tuberculosis Haarlem)	5e-19	41
214) TBMG_01212   ( YP_003031156.1 )	dihydrofolate reductase dfrA	NC_012943 (Mycobacterium tuberculosis KZN 1435)	5e-19	41
215) TBSG_01222   ( YP_005099690.1 )	dihydrofolate reductase dfrA	NC_016768 (Mycobacterium tuberculosis KZN 4207)	5e-19	41
216) TBXG_001202   ( YP_006472675.1 )	dihydrofolate reductase dfrA	NC_018078 (Mycobacterium tuberculosis KZN 605)	5e-19	41
217) MRGA423_17145   ( YP_005923916.1 )	dihydrofolate reductase	NC_017528 (Mycobacterium tuberculosis RGTB423)	5e-19	41
218) dfrA   ( YP_005309024.1 )	hypothetical protein	NC_016934 (Mycobacterium tuberculosis UT205)	5e-19	41
219) O159_15960   ( YP_008580218.1 )	dihydrofolate reductase	NC_022438 (Leifsonia xyli DSM 46306)	1e-18	42
220) folA   ( YP_005932902.1 )	dihydrofolate reductase FolA	NC_017531 (Pantoea ananatis AJ13355)	1e-18	42
221) folA   ( YP_003518975.1 )	FolA	NC_013956 (Pantoea ananatis LMG 20103)	1e-18	42
222) folA   ( YP_005197061.1 )	dihydrofolate reductase type I	NC_016816 (Pantoea ananatis LMG 5342)	1e-18	42
223) PAGR_g3518   ( YP_005994230.1 )	dihydrofolate reductase FolA	NC_017554 (Pantoea ananatis PA13)	1e-18	42
224) Dsui_1240   ( YP_005027481.1 )	dihydrofolate reductase	NC_016616 (Dechlorosoma suillum PS)	2e-18	41
225) D781_0673   ( YP_007343206.1 )	dihydrofolate reductase	NC_020064 (Serratia marcescens FGI94)	4e-18	41
226) I917_19365   ( YP_007958771.1 )	dihydrofolate reductase	NC_021192 (Mycobacterium tuberculosis Haarlem/NITR202)	5e-18	42
227) Mycsm_02511   ( YP_007292251.1 )	dihydrofolate reductase	NC_019966 (Mycobacterium smegmatis JS623)	1e-17	41
228) RPC_3263   ( YP_533124.1 )	dihydrofolate reductase	NC_007925 (Rhodopseudomonas palustris BisB18)	1e-17	41
229) folA   ( YP_003714179.1 )	dihydrofolate reductase	NC_014228 (Xenorhabdus nematophila ATCC 19061)	1e-17	41
230) dfrA   ( YP_004523763.1 )	dihydrofolate reductase DfrA	NC_015576 (Mycobacterium sp. JDM601)	1e-17	42
231) folA   ( YP_006350571.1 )	dihydrofolate reductase	NC_017941 (Haloferax mediterranei CGMCC 1.2087)	1e-17	41
232) folA   ( YP_008136799.1 )	dihydrofolate reductase FolA	NC_021591 (Serratia odorifera 4Rx13)	1e-17	41
233) folA   ( YP_008157463.1 )	dihydrofolate reductase	NC_021659 (Serratia plymuthica S13)	1e-17	41
234) Dd586_3577   ( YP_003335113.1 )	Dihydrofolate reductase	NC_013592 (Dickeya dadantii Ech586)	2e-17	41
235) NMBM01240355_0319   ( YP_005900995.1 )	dihydrofolate reductase	NC_017517 (Neisseria meningitidis M01-240355)	2e-17	45
236) Hmuk_1491   ( YP_003177313.1 )	dihydrofolate reductase subunit	NC_013202 (Halomicrobium mukohataei DSM 12286)	5e-17	41
237) folA   ( YP_005040395.1 )	dihydrofolate reductase	NC_016622 (Azospirillum lipoferum 4B)	5e-17	44
238) MycrhN_5637   ( YP_005003320.1 )	dihydrofolate reductase	NC_016604 (Mycobacterium rhodesiae NBB3)	7e-17	42
239) folA   ( YP_005282475.1 )	dihydrofolate reductase FolA	NC_016906 (Gordonia polyisoprenivorans VH2)	9e-17	42
240) NGK_2087   ( YP_002002712.1 )	protein FolA	NC_011035 (Neisseria gonorrhoeae NCCP11945)	1e-16	44
241) folA   ( YP_007347141.1 )	dihydrofolate reductase	NC_020075 (Candidatus Blochmannia chromaiodes 640)	1e-16	42
242) Pfl01_5361   ( YP_351089.1 )	dihydrofolate reductase	NC_007492 (Pseudomonas fluorescens Pf0-1)	1e-16	41
243) folA   ( YP_007404532.1 )	dihydrofolate reductase	NC_020211 (Serratia marcescens WW4)	2e-16	43
244) folA   ( YP_003002920.1 )	dihydrofolate reductase	NC_012912 (Dickeya zeae Ech1591)	2e-16	41
245) folA   ( YP_005892674.1 )	dihydrofolate reductase	NC_017512 (Neisseria meningitidis WUE 2594)	1e-15	44
246) NMA2179   ( YP_002343426.1 )	dihydrofolate reductase	NC_003116 (Neisseria meningitidis Z2491)	1e-15	44
247) NMBB_0341   ( YP_005881971.1 )	dihydrofolate reductase	NC_017505 (Neisseria meningitidis alpha710)	1e-15	44
248) NMBH4476_0303   ( YP_005899014.1 )	dihydrofolate reductase	NC_017516 (Neisseria meningitidis H44/76)	1e-15	44
249) NMBM01240149_1775   ( YP_005896534.1 )	dihydrofolate reductase	NC_017514 (Neisseria meningitidis M01-240149)	1e-15	44
250) folA   ( YP_005897079.1 )	dihydrofolate reductase	NC_017515 (Neisseria meningitidis M04-240196)	1e-15	44
251) folA   ( NP_273358.1 )	dihydrofolate reductase	NC_003112 (Neisseria meningitidis MC58)	1e-15	44
252) folA   ( YP_005904485.1 )	dihydrofolate reductase	NC_017518 (Neisseria meningitidis NZ-05/33)	1e-15	44
253) Swit_3786   ( YP_001264269.1 )	dihydrofolate reductase	NC_009511 (Sphingomonas wittichii RW1)	1e-15	41
254) folA   ( YP_003083877.1 )	Dihydrofolate reductase	NC_013016 (Neisseria meningitidis alpha14)	1e-15	44
255) folA   ( YP_004047995.1 )	dihydrofolate reductase	NC_014752 (Neisseria lactamica 020-06)	1e-15	43
256) folA   ( YP_001599935.1 )	dihydrofolate reductase	NC_010120 (Neisseria meningitidis 053442)	1e-15	43
257) NMBG2136_1790   ( YP_005894627.1 )	dihydrofolate reductase	NC_017513 (Neisseria meningitidis G2136)	2e-15	43
258) folA   ( YP_975807.1 )	dihydrofolate reductase	NC_008767 (Neisseria meningitidis FAM18)	3e-15	43
259) folA   ( YP_005030179.1 )	dihydrofolate reductase	NC_016617 (Azospirillum brasilense Sp245)	3e-15	42
260) folA   ( YP_005877887.1 )	dihydrofolate reductase	NC_017501 (Neisseria meningitidis 8013)	8e-15	43
261) Saro_3262   ( YP_498531.1 )	dihydrofolate reductase	NC_007794 (Novosphingobium aromaticivorans DSM 12444)	2e-14	41