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PAthogenisity Island DataBase (PAI DB)

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Homologs of tcpA gene of AF325734

protein-level

Hit (GenBank Accn)

Product

Source Genome

Eval.

Ident.(%)

• Sequence Alignments

1) O3Y_03850 in NC_016944


> AF325734|11|G11|13377550|AAK20785.1|Vibrio_cholerae_O1_biovar_eltor_str._N16961|+|17431..18105|tcpA|-|toxin-coregulated 
pilin
Length=224

 Score =  301 bits (1127),  Expect = 2e-83, Method: Compositional matrix adjust.
 Identities = 204/204 (100%), Positives = 204/204 (100%), Gaps = 0/204 (0%)

Query  21   TGQEGMTLLEVIIVLGIMGVVSAGVVTLAQRAIDSQNMTKAAQNLNSVQIAMTQTYRSLG  80
            TGQEGMTLLEVIIVLGIMGVVSAGVVTLAQRAIDSQNMTKAAQNLNSVQIAMTQTYRSLG
Sbjct  21   TGQEGMTLLEVIIVLGIMGVVSAGVVTLAQRAIDSQNMTKAAQNLNSVQIAMTQTYRSLG  80

Query  81   NYPatananaatQLANGLVSLGKVSADEAKNPFTGTAMGIFSFPRNSAANKAFAITVGGL  140
            NYPATANANAATQLANGLVSLGKVSADEAKNPFTGTAMGIFSFPRNSAANKAFAITVGGL
Sbjct  81   NYPATANANAATQLANGLVSLGKVSADEAKNPFTGTAMGIFSFPRNSAANKAFAITVGGL  140

Query  141  TQAQCKTLVTSVGDMFPFINVKEGAFAAVADLGDFETSVADAATGAGVIKSIAPGSANLN  200
            TQAQCKTLVTSVGDMFPFINVKEGAFAAVADLGDFETSVADAATGAGVIKSIAPGSANLN
Sbjct  141  TQAQCKTLVTSVGDMFPFINVKEGAFAAVADLGDFETSVADAATGAGVIKSIAPGSANLN  200

Query  201  LTNITHVEKLCTGTAPFTVAFGNS  224
            LTNITHVEKLCTGTAPFTVAFGNS
Sbjct  201  LTNITHVEKLCTGTAPFTVAFGNS  224

2) tcpA in NC_012578


> AF325734|11|G11|13377550|AAK20785.1|Vibrio_cholerae_O1_biovar_eltor_str._N16961|+|17431..18105|tcpA|-|toxin-coregulated 
pilin
Length=224

 Score =  301 bits (1127),  Expect = 2e-83, Method: Compositional matrix adjust.
 Identities = 204/204 (100%), Positives = 204/204 (100%), Gaps = 0/204 (0%)

Query  21   TGQEGMTLLEVIIVLGIMGVVSAGVVTLAQRAIDSQNMTKAAQNLNSVQIAMTQTYRSLG  80
            TGQEGMTLLEVIIVLGIMGVVSAGVVTLAQRAIDSQNMTKAAQNLNSVQIAMTQTYRSLG
Sbjct  21   TGQEGMTLLEVIIVLGIMGVVSAGVVTLAQRAIDSQNMTKAAQNLNSVQIAMTQTYRSLG  80

Query  81   NYPatananaatQLANGLVSLGKVSADEAKNPFTGTAMGIFSFPRNSAANKAFAITVGGL  140
            NYPATANANAATQLANGLVSLGKVSADEAKNPFTGTAMGIFSFPRNSAANKAFAITVGGL
Sbjct  81   NYPATANANAATQLANGLVSLGKVSADEAKNPFTGTAMGIFSFPRNSAANKAFAITVGGL  140

Query  141  TQAQCKTLVTSVGDMFPFINVKEGAFAAVADLGDFETSVADAATGAGVIKSIAPGSANLN  200
            TQAQCKTLVTSVGDMFPFINVKEGAFAAVADLGDFETSVADAATGAGVIKSIAPGSANLN
Sbjct  141  TQAQCKTLVTSVGDMFPFINVKEGAFAAVADLGDFETSVADAATGAGVIKSIAPGSANLN  200

Query  201  LTNITHVEKLCTGTAPFTVAFGNS  224
            LTNITHVEKLCTGTAPFTVAFGNS
Sbjct  201  LTNITHVEKLCTGTAPFTVAFGNS  224

3) VCD_003500 in NC_012668


> AF325734|11|G11|13377550|AAK20785.1|Vibrio_cholerae_O1_biovar_eltor_str._N16961|+|17431..18105|tcpA|-|toxin-coregulated 
pilin
Length=224

 Score =  301 bits (1127),  Expect = 2e-83, Method: Compositional matrix adjust.
 Identities = 204/204 (100%), Positives = 204/204 (100%), Gaps = 0/204 (0%)

Query  21   TGQEGMTLLEVIIVLGIMGVVSAGVVTLAQRAIDSQNMTKAAQNLNSVQIAMTQTYRSLG  80
            TGQEGMTLLEVIIVLGIMGVVSAGVVTLAQRAIDSQNMTKAAQNLNSVQIAMTQTYRSLG
Sbjct  21   TGQEGMTLLEVIIVLGIMGVVSAGVVTLAQRAIDSQNMTKAAQNLNSVQIAMTQTYRSLG  80

Query  81   NYPatananaatQLANGLVSLGKVSADEAKNPFTGTAMGIFSFPRNSAANKAFAITVGGL  140
            NYPATANANAATQLANGLVSLGKVSADEAKNPFTGTAMGIFSFPRNSAANKAFAITVGGL
Sbjct  81   NYPATANANAATQLANGLVSLGKVSADEAKNPFTGTAMGIFSFPRNSAANKAFAITVGGL  140

Query  141  TQAQCKTLVTSVGDMFPFINVKEGAFAAVADLGDFETSVADAATGAGVIKSIAPGSANLN  200
            TQAQCKTLVTSVGDMFPFINVKEGAFAAVADLGDFETSVADAATGAGVIKSIAPGSANLN
Sbjct  141  TQAQCKTLVTSVGDMFPFINVKEGAFAAVADLGDFETSVADAATGAGVIKSIAPGSANLN  200

Query  201  LTNITHVEKLCTGTAPFTVAFGNS  224
            LTNITHVEKLCTGTAPFTVAFGNS
Sbjct  201  LTNITHVEKLCTGTAPFTVAFGNS  224

4) VC0828 in NC_002505


> AF325734|11|G11|13377550|AAK20785.1|Vibrio_cholerae_O1_biovar_eltor_str._N16961|+|17431..18105|tcpA|-|toxin-coregulated 
pilin
Length=224

 Score =  301 bits (1127),  Expect = 2e-83, Method: Compositional matrix adjust.
 Identities = 204/204 (100%), Positives = 204/204 (100%), Gaps = 0/204 (0%)

Query  21   TGQEGMTLLEVIIVLGIMGVVSAGVVTLAQRAIDSQNMTKAAQNLNSVQIAMTQTYRSLG  80
            TGQEGMTLLEVIIVLGIMGVVSAGVVTLAQRAIDSQNMTKAAQNLNSVQIAMTQTYRSLG
Sbjct  21   TGQEGMTLLEVIIVLGIMGVVSAGVVTLAQRAIDSQNMTKAAQNLNSVQIAMTQTYRSLG  80

Query  81   NYPatananaatQLANGLVSLGKVSADEAKNPFTGTAMGIFSFPRNSAANKAFAITVGGL  140
            NYPATANANAATQLANGLVSLGKVSADEAKNPFTGTAMGIFSFPRNSAANKAFAITVGGL
Sbjct  81   NYPATANANAATQLANGLVSLGKVSADEAKNPFTGTAMGIFSFPRNSAANKAFAITVGGL  140

Query  141  TQAQCKTLVTSVGDMFPFINVKEGAFAAVADLGDFETSVADAATGAGVIKSIAPGSANLN  200
            TQAQCKTLVTSVGDMFPFINVKEGAFAAVADLGDFETSVADAATGAGVIKSIAPGSANLN
Sbjct  141  TQAQCKTLVTSVGDMFPFINVKEGAFAAVADLGDFETSVADAATGAGVIKSIAPGSANLN  200

Query  201  LTNITHVEKLCTGTAPFTVAFGNS  224
            LTNITHVEKLCTGTAPFTVAFGNS
Sbjct  201  LTNITHVEKLCTGTAPFTVAFGNS  224

5) tcpA in NC_016445


> AF325734|11|G11|13377550|AAK20785.1|Vibrio_cholerae_O1_biovar_eltor_str._N16961|+|17431..18105|tcpA|-|toxin-coregulated 
pilin
Length=224

 Score =  294 bits (1101),  Expect = 2e-81, Method: Compositional matrix adjust.
 Identities = 203/204 (99%), Positives = 204/204 (100%), Gaps = 0/204 (0%)

Query  21   TGQEGMTLLEVIIVLGIMGVVSAGVVTLAQRAIDSQNMTKAAQNLNSVQIAMTQTYRSLG  80
            TGQEGMTLLEVIIVLGIMGVVSAGVVTLAQRAIDSQNMTKAAQNLNSVQIAMTQTYRSLG
Sbjct  21   TGQEGMTLLEVIIVLGIMGVVSAGVVTLAQRAIDSQNMTKAAQNLNSVQIAMTQTYRSLG  80

Query  81   NYPatanasaatqlanGLVSLGKVSADEAKNPFTGTAMGIFSFPRNSAANKAFAITVGGL  140
            NYPATANA+AATQLANGLVSLGKVSADEAKNPFTGTAMGIFSFPRNSAANKAFAITVGGL
Sbjct  81   NYPATANANAATQLANGLVSLGKVSADEAKNPFTGTAMGIFSFPRNSAANKAFAITVGGL  140

Query  141  TQAQCKTLVTSVGDMFPFINVKEGAFAAVADLGDFETSVADAATGAGVIKSIAPGSANLN  200
            TQAQCKTLVTSVGDMFPFINVKEGAFAAVADLGDFETSVADAATGAGVIKSIAPGSANLN
Sbjct  141  TQAQCKTLVTSVGDMFPFINVKEGAFAAVADLGDFETSVADAATGAGVIKSIAPGSANLN  200

Query  201  LTNITHVEKLCTGTAPFTVAFGNS  224
            LTNITHVEKLCTGTAPFTVAFGNS
Sbjct  201  LTNITHVEKLCTGTAPFTVAFGNS  224

6) tcpA in NC_012582


> AF325734|11|G11|13377550|AAK20785.1|Vibrio_cholerae_O1_biovar_eltor_str._N16961|+|17431..18105|tcpA|-|toxin-coregulated 
pilin
Length=224

 Score =  257 bits (962),  Expect = 2e-70, Method: Compositional matrix adjust.
 Identities = 166/204 (82%), Positives = 188/204 (93%), Gaps = 0/204 (0%)

Query  21   TGQEGMTLLEVIIVLGIMGVVSAGVVTLAQRAIDSQNMTKAAQSLNSIQVALTQTYRGLG  80
            TGQEGMTLLEVIIVLGIMGVVSAGVVTLAQRAIDSQNMTKAAQ+LNS+Q+A+TQTYR+LG
Sbjct  21   TGQEGMTLLEVIIVLGIMGVVSAGVVTLAQRAIDSQNMTKAAQNLNSVQIAMTQTYRSLG  80

Query  81   NYPATADATAASKLTSGLVSLGKISSDEAKNPFIGTNMNIFSFPRNAAANKAFAISVDGL  140
            NYPATA+A AA++L++GLVSLGK+S+DEAKNPF GT M IFSFPRN+AANKAFAI+V+GL
Sbjct  81   NYPATANANAATQLANGLVSLGKVSADEAKNPFTGTAMGIFSFPRNSAANKAFAITVGGL  140

Query  141  TQAQCKTLITSVGDMFPYIAIKaggavaladlgdFENSAAAAETGVGVIKSIAPASKNLD  200
            TQAQCKTL+TSVGDMFP+I +K G+  A+ADLGDFE S A A TG GVIKSIAP+S NL+
Sbjct  141  TQAQCKTLVTSVGDMFPFINVKEGAFAAVADLGDFETSVADAATGAGVIKSIAPGSANLN  200

Query  201  LTNITHVEKLCKGTAPFGVAFGNS  224
            LTNITHVEKLC GTAPF VAFGNS
Sbjct  201  LTNITHVEKLCTGTAPFTVAFGNS  224

7) tcpA in NC_009457


> AF325734|11|G11|13377550|AAK20785.1|Vibrio_cholerae_O1_biovar_eltor_str._N16961|+|17431..18105|tcpA|-|toxin-coregulated 
pilin
Length=224

 Score =  257 bits (962),  Expect = 2e-70, Method: Compositional matrix adjust.
 Identities = 166/204 (82%), Positives = 188/204 (93%), Gaps = 0/204 (0%)

Query  21   TGQEGMTLLEVIIVLGIMGVVSAGVVTLAQRAIDSQNMTKAAQSLNSIQVALTQTYRGLG  80
            TGQEGMTLLEVIIVLGIMGVVSAGVVTLAQRAIDSQNMTKAAQ+LNS+Q+A+TQTYR+LG
Sbjct  21   TGQEGMTLLEVIIVLGIMGVVSAGVVTLAQRAIDSQNMTKAAQNLNSVQIAMTQTYRSLG  80

Query  81   NYPATADATAASKLTSGLVSLGKISSDEAKNPFIGTNMNIFSFPRNAAANKAFAISVDGL  140
            NYPATA+A AA++L++GLVSLGK+S+DEAKNPF GT M IFSFPRN+AANKAFAI+V+GL
Sbjct  81   NYPATANANAATQLANGLVSLGKVSADEAKNPFTGTAMGIFSFPRNSAANKAFAITVGGL  140

Query  141  TQAQCKTLITSVGDMFPYIAIKaggavaladlgdFENSAAAAETGVGVIKSIAPASKNLD  200
            TQAQCKTL+TSVGDMFP+I +K G+  A+ADLGDFE S A A TG GVIKSIAP+S NL+
Sbjct  141  TQAQCKTLVTSVGDMFPFINVKEGAFAAVADLGDFETSVADAATGAGVIKSIAPGSANLN  200

Query  201  LTNITHVEKLCKGTAPFGVAFGNS  224
            LTNITHVEKLC GTAPF VAFGNS
Sbjct  201  LTNITHVEKLCTGTAPFTVAFGNS  224

8) tcpA in NC_006841


> AF325734|11|G11|13377550|AAK20785.1|Vibrio_cholerae_O1_biovar_eltor_str._N16961|+|17431..18105|tcpA|-|toxin-coregulated 
pilin
Length=224

 Score =  158 bits (584),  Expect = 1e-40, Method: Compositional matrix adjust.
 Identities = 97/195 (50%), Positives = 145/195 (75%), Gaps = 5/195 (2%)

Query  6    QRGMTLLEVIIVLGIMGVISAGVVILAQRAIDNQNVSKLSQALNTIQTAMVQTYRSKQSY  65
            Q GMTLLEVIIVLGIMGV+SAGVV LAQRAID+QN++K +Q LN++Q AM QTYRS  +Y
Sbjct  23   QEGMTLLEVIIVLGIMGVVSAGVVTLAQRAIDSQNMTKAAQNLNSVQIAMTQTYRSLGNY  82

Query  66   PDVLQDAVKAKKLTDALVSMGRVTESDLINPFTGAPMLIFTAKDNKAANRGFAIKVSDLS  125
            P    +A  A +L+++LVS+G+V+  +  NPFTG++M IF+   N AAN++FAI V++L+
Sbjct  83   PAT-ANANAATQLANGLVSLGKVSADEAKNPFTGTAMGIFSFPRNSAANKAFAITVGGLT  141

Query  126  KDQCTSLISNSADLFSFIEVQNRGTAMAADF--YVD--PDATKSVGVIKSTKGGAKTLDL  181
            + QC +L+++ +D+F+FI+V++ + A  AD+  +    +DA+ + GVIKS   G+  L+L
Sbjct  142  QAQCKTLVTSVGDMFPFINVKEGAFAAVADLGDFETSVADAATGAGVIKSIAPGSANLNL  201

Query  182  TNLDHISALCGGPGA  196
            TN+ H+  LC G ++
Sbjct  202  TNITHVEKLCTGTAP  216