> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  900 bits (3409),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 520/672 (78%), Positives = 622/672 (93%), Gaps = 2/672 (0%)

Query  1    MRVFLCEKPSQGKDIARVLGAGQRGNGCYSGASVVVTWCIGHLVEAVPPEGYGEQYKRWA  60
            MR+FLCEKPSQGKDIARVLGAGQRG+GCY+GA+ VVTWCIGHL+EA PPE+YGEQYKRW+
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQYKRWS  60

Query  61   IEQLPIVPERWRVEPKAATVAQFKVVQQLVAKAGELVIATDADREGEMIAREIIDLCGYR  120
            +EQLPI+PERWRVEPKAAT AQ+K+V+QLV++A+ELVIATDADREGEMIAREIIDLCGYR
Sbjct  61   LEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGYR  120

Query  121  GPIQRLWLSALNDASIRKALGALKPSAETMPLYFSALARSRADWLIGMNLSRLFTLLGRQ  180
            GPIQRLWLSALNDASIRKALGALKPS+E++PLY +ALARSRADWL+GMNLSRLFTLLGRQ
Sbjct  121  GPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGRQ  180

Query  181  AGYNGVLSVGRVQTPTLKLVVDRDREIARFVSVPFWATEVALSHAGQTFVASWTPPQGST  240
            AGY+GVLSVGRVQTPTL LVV RDREIARFVSVPFW+ EV+LS +G++F+A+W +++G +
Sbjct  181  AGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGCS  240

Query  241  DEAGRCLRQPVAQQAAERLRAAGTAQVLSVETERVREGPPLPFDLGTLQEVCSKQLGLDV  300
            D+AGRCL+Q+ AQQAA+RLR AG+AQV++V TERVRE+PPLPFDLGTLQ+VCS+QL+LDV
Sbjct  241  DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALDV  300

Query  301  QETLDIAQALYETHKATTYPRSDSGHLPESMLAEVPAVLDSLVKTDPSLRPLIDRLDRQQ  360
            QETLDIAQALYETHKATTYPRSDSG LPESMLAEVPAVL +++ TDPSLRPL+++LDR Q
Sbjct  301  QETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRTQ  360

Query  361  RSRAWNDGKVTAHHGIIPTLEPANLSAMTEKELAVYRLIRAHYLAQFLPHHEFDRTVAQL  420
            RSRAWND+KV+AHHGIIPTLEPANL+A+++K LAVYRLIRAHYLAQFLPH EFDRT AQL
Sbjct  361  RSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQL  420

Query  421  TCGGQSLVAVGKQIATAGWRQVLAAPALDDTDGEDARRGQVLPALKAGDACQVSQVELKA  480
             CGGQ+L AVGKQ+  +GW+QVLA+P  D++DGE   R+QVLPAL+ G +CQV++V+LKA
Sbjct  421  LCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLSCQVNHVDLKA  480

Query  481  LKTLPPKPYTQGELVKAMKGVAKLVTDPRLKQKLKDTTGIGTEATRANIISGLLARGYLL  540
            LKT PPKPYTQG+L+KAMKGVAKLVTDPRLKQKLK+TTGIGTEATRA+II GLL RGYLL
Sbjct  481  LKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERGYLL  540

Query  541  KKGRAIRASDAAFTLIDAVPAAIADPGTTAVWEHALDMIEAGQMALDTFIAKQSSWVARL  600
            KKGR++RASDAA  LIDAVPAAI+DPGTTAVWE+ALDMIEAG+M+L+TF+AKQS+W+++L
Sbjct  541  KKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWITQL  600

Query  601  VQQYRGATLDLKLPPAPDCPQCGAPMRQRSSKSGVFWSCSRYPDCKGTQPVEDA--AAGK  658
            VQQYR+ATL +KLP +P CP CG++ RQR++K+G FWSC RYPDCKGT PV+++  A++K
Sbjct  601  VQQYRAATLAIKLPEGPACPLCGSATRQRTGKTGPFWSCCRYPDCKGTLPVQNGRQASAK  660

Query  659  RGASSRTYRAPR  670
            R++S +  + P+
Sbjct  661  RSTSRKPRQIPK  672

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  891 bits (3375),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 529/674 (79%), Positives = 621/674 (93%), Gaps = 5/674 (0%)

Query  1    MRVFLCEKPSQGKDIARVLGAGQRRNGCYSGAGIVVTWCIGHLVEAVPPEGYDERDKRWV  60
            MR+FLCEKPSQGKDIARVLGAGQR +GCY+GAG VVTWCIGHL+EA PPE+Y+E+ KRW 
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQYKRWS  60

Query  61   IEQLPIIPERWRVEPKAATAAQFKIVKQLVGQATELVIATDADREGEMIAREIIELCGYR  120
            +EQLPIIPERWRVEPKAATAAQ+KIVKQLVGQA+ELVIATDADREGEMIAREII+LCGYR
Sbjct  61   LEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGYR  120

Query  121  GAIQRLWLSALNDASIRKALGALKSSAETLPLYYSALARSRADWLIGMNLSRLFTLLGRQ  180
            G+IQRLWLSALNDASIRKALGALK+S+E+LPLY +ALARSRADWL+GMNLSRLFTLLGRQ
Sbjct  121  GPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGRQ  180

Query  181  AGYTGVLSVGRVQTPTLKLVVDRDREIARFVSAPFWAVEVALSHAGQPFTASWTPPEGCT  240
            AGY GVLSVGRVQTPTL LVV RDREIARFVS PFW++EV+LS +G++F A+W +++GC+
Sbjct  181  AGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGCS  240

Query  241  DEAGRCLQQPVAQQAAERMRATGSAQVASVETERVREGPPLPFDLGTLQELCSQQLGLDV  300
            D+AGRCLQQ+ AQQAA+R+R +GSAQV +V TERVRE+PPLPFDLGTLQ++CS+QL+LDV
Sbjct  241  DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALDV  300

Query  301  QETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPTVLDSLVKTDPSLRPLIDRLDRNQ  360
            QETLDIAQALYETHKATTYPRSDSGYLPESMLAEVP+VL +++ TDPSLRPL+++LDR Q
Sbjct  301  QETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRTQ  360

Query  361  RSRAWSDAKVTAHHGIIPTLEPANLSAMNDKELAVYKLIRAHYLAQFLPHHEFDRTVAEL  420
            RSRAW+D+KV+AHHGIIPTLEPANL+A++DK LAVY+LIRAHYLAQFLPH EFDRT A+L
Sbjct  361  RSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQL  420

Query  421  ACGGQSLLAVGKQIAVAGWRQVLASSEEGGADSDDAQRSQVLPALRAGLSCQVGHVDLKA  480
             CGGQ+L AVGKQ+ ++GW+QVLA++E + AD++   RSQVLPALR GLSCQV HVDLKA
Sbjct  421  LCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLSCQVNHVDLKA  480

Query  481  LKTLPPKPYTQGELVKAMKGVARLVTDPRLKQKLKDTTGIGTEATRANIISGLLGRGYLL  540
            LKT PPKPYTQG+L+KAMKGVA+LVTDPRLKQKLK+TTGIGTEATRA+II GLL RGYLL
Sbjct  481  LKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERGYLL  540

Query  541  TKGRAVRASDAAFTLIDTVPAAIADPGTTAVWEQALDMIEAGQMTLDAFIAKQSAWVTQL  600
             KGR+VRASDAA  LID+VPAAI+DPGTTAVWEQALDMIEAG+MTL++F+AKQS+W+TQL
Sbjct  541  KKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWITQL  600

Query  601  VQQYRGTTLAIKLppspspscpQCGAPMRQRTGKSGAFWSCSRYPDCKGTLPVDT---ST  657
            VQQYR++TLAIKLP +P+ +   CG++ RQRTGK+G+FWSC RYPDCKGTLPV+    ++
Sbjct  601  VQQYRAATLAIKLPEGPACPL--CGSATRQRTGKTGPFWSCCRYPDCKGTLPVQNGRQAS  658

Query  658  GKRSASRKQRASPK  671
            +KRS+SRK R  PK
Sbjct  659  AKRSTSRKPRQIPK  672

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  880 bits (3334),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 520/653 (80%), Positives = 602/653 (93%), Gaps = 0/653 (0%)

Query  1    MRVFLCEKPSQGKDIARVLGAGQRGNGYYSGAGVVVTWCIGHLVEAVPPEGYGEQYKRWA  60
            MR+FLCEKPSQGKDIARVLGAGQRG+G Y+GAG VVTWCIGHL+EA PPE+YGEQYKRW+
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQYKRWS  60

Query  61   IEQLPILPERWRVEPKAATAAQFKVVQQLVAKAGELVIATDADREGEMIAREIIDLCGYH  120
            +EQLPI+PERWRVEPKAATAAQ+K+V+QLV++A+ELVIATDADREGEMIAREIIDLCGY+
Sbjct  61   LEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGYR  120

Query  121  GPIQRLWLSALNDASIRKALGALKPSAETLPLYYSALARSRADWLIGMNLSRLFTLLGRQ  180
            GPIQRLWLSALNDASIRKALGALKPS+E+LPLY +ALARSRADWL+GMNLSRLFTLLGRQ
Sbjct  121  GPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGRQ  180

Query  181  AGYTGVLSVGRVQTPTLKLVVDRDREIARFVSVPYWAVDVLLSHAGRSFTASWIPPEGST  240
            AGY GVLSVGRVQTPTL LVV RDREIARFVSVP+W+++V LS +G+SF A+WI+++G +
Sbjct  181  AGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGCS  240

Query  241  DAAGRCLQQPVAQQAADCIRAARDAQVVSVDTERVREAPPLPFDLGTLQEVCSKQLGLDV  300
            D AGRCLQQ+ AQQAAD +R A  AQVV+V TERVREAPPLPFDLGTLQ+VCS+QL+LDV
Sbjct  241  DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALDV  300

Query  301  QETLDIAQALYETHKATTYPRSDSGYLPESMLAKVPAVLDALLATDPSLRPLIGQLDRNQ  360
            QETLDIAQALYETHKATTYPRSDSGYLPESMLA VPAVL A+L+TDPSLRPL+ QLDR Q
Sbjct  301  QETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRTQ  360

Query  361  RSRAWNDGKVTAHHGIIPTLEPANLSAMNEKELAVYRLIRAHYLAQFLPHHEFDRTVAQF  420
            RSRAWND+KV+AHHGIIPTLEPANL+A+++K LAVYRLIRAHYLAQFLPH EFDRT AQ+
Sbjct  361  RSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQL  420

Query  421  SCGSQSLAAVGKQIAVTGWREVLATPGPDDADGEDAQRSQVLPALHAGLSCPVGKVDLKA  480
             CG+Q+L AVGKQ+ + GW++VLA P +D+ADGE   RSQVLPAL+ GLSC V  VDLKA
Sbjct  421  LCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLSCQVNHVDLKA  480

Query  481  LKTLPPKPYTQGELIKAMKTVAKFVTDPRLKQKLRDTTGIGTEATRANIINGLIGRGYLV  540
            LKT PPKPYTQG+LIKAMK VAK+VTDPRLKQKL++TTGIGTEATRA+II+GL+ RGYL+
Sbjct  481  LKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERGYLL  540

Query  541  KKGRAVRASDAAFTLIDAVPSAIADPGTTAVWEQALDMIEAGQMALDTFIEKQSVWVGQL  600
            KKGR+VRASDAA  LIDAVP+AI+DPGTTAVWEQALDMIEAG+M+L+TF+ KQS W+ QL
Sbjct  541  KKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWITQL  600

Query  601  VQQYRGATLSLKLPPTPACPQCGAPMQQRTGKSGAFWSCSRYPDCKGTLPIES  653
            VQQYR+ATL++KLP  PACP CG++ +QRTGK+G+FWSC RYPDCKGTLP+++
Sbjct  601  VQQYRAATLAIKLPEGPACPLCGSATRQRTGKTGPFWSCCRYPDCKGTLPVQN  653

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  877 bits (3320),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 512/652 (79%), Positives = 600/652 (93%), Gaps = 0/652 (0%)

Query  1    MRVFLCEKPSQGKDIARVLGARQRGNGCYSGSGITVTWCIGHLVEAAPPETYGEQYKQWS  60
            MR+FLCEKPSQGKDIARVLGA QRG+GCY+G+G  VTWCIGHL+EAAPPE+YGEQYK+WS
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQYKRWS  60

Query  61   IEQLPILPERWRIEVKAKTAAQFKIVKQFVAQAGELVIATDADREGEMIAREIIDLCGYR  120
            +EQLPI+PERWR+E KA TAAQ+KIVKQ+V+QA+ELVIATDADREGEMIAREIIDLCGYR
Sbjct  61   LEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGYR  120

Query  121  GPIQRLWLSALNDASIRKALTQLKPGGETLPLYFSALARSRADWLIGMNLSRLFTVLGRR  180
            GPIQRLWLSALNDASIRKAL  LKP++E+LPLY +ALARSRADWL+GMNLSRLFT+LGR+
Sbjct  121  GPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGRQ  180

Query  181  SGYQGVLSVGRVQTPTLKLVVDRDREIARFVSVPYWTIDVTLSHAGQSFAASWMPPDGTT  240
            +GY+GVLSVGRVQTPTL LVV RDREIARFVSVP+W+I+V LS +G+SF A+W+++DG +
Sbjct  181  AGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGCS  240

Query  241  DAAGRCLQQPVAQQAADRIRAGRESKVLSVETERVREAAPLPFDLGTLQEVCSRQLGLDV  300
            D AGRCLQQ+ AQQAADR+R +  ++V++V TERVREA+PLPFDLGTLQ+VCSRQL+LDV
Sbjct  241  DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALDV  300

Query  301  QETLDIAQSLYETHKATTYPRSDSGYLPESMLAEVPTVLDALLATDPGLRPLIDRLDRTQ  360
            QETLDIAQ+LYETHKATTYPRSDSGYLPESMLAEVP+VL A+L+TDP+LRPL+++LDRTQ
Sbjct  301  QETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRTQ  360

Query  361  RSRVWNDSKITAHHGIIPTLEPANLSAMSEKELAVYALIRAHYLAQFLPHHEFDRTLVML  420
            RSR WNDSK++AHHGIIPTLEPANL+A+S+K LAVY LIRAHYLAQFLPH EFDRT   L
Sbjct  361  RSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQL  420

Query  421  DCAGQSLQAVGKRVIVPGWHLALPGKGQDAADDEPAQRSQILPPLDTGARCGVQQVELKA  480
             C+GQ+LQAVGK+VI+PGWH  L+G   D AD+E+  RSQ+LP+L  G  C V++V+LKA
Sbjct  421  LCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLSCQVNHVDLKA  480

Query  481  LKTLPPKPYTQGELIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRAGIINGLLARGYLV  540
            LKT PPKPYTQG+LIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRA+II+GLL RGYL+
Sbjct  481  LKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERGYLL  540

Query  541  KKGRAIRASDAAFTLIDAVPAAITDPGTTAIWEQALDMIEAGQMTLDTFINKQSAWVAQL  600
            KKGR++RASDAA  LIDAVPAAITDPGTTA+WEQALDMIEAG+MTL+TF+ KQS+W++QL
Sbjct  541  KKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWITQL  600

Query  601  VQQYRGTVLSIKLPEGPACPVCGAATRQRNGKNGAFWSCSRYPDCKGTLPAE  652
            VQQYR++ L+IKLPEGPACP+CG+ATRQR GK G+FWSC RYPDCKGTLP +
Sbjct  601  VQQYRAATLAIKLPEGPACPLCGSATRQRTGKTGPFWSCCRYPDCKGTLPVQ  652

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  873 bits (3308),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 524/653 (81%), Positives = 606/653 (93%), Gaps = 0/653 (0%)

Query  1    MRVFLCEKPSQGKDIARVLGAGQRGNGCYSGAGVVVTWCIGHLVEAVPPEGYGEQYKRWA  60
            MR+FLCEKPSQGKDIARVLGAGQRG+GCY+GAG VVTWCIGHL+EA PPE+YGEQYKRW+
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQYKRWS  60

Query  61   IEQLPILPERWRVEPKAATAAQFKVVQQLVAKAGELVIATDADREGEMIAREIIDLCGYR  120
            +EQLPI+PERWRVEPKAATAAQ+K+V+QLV++A+ELVIATDADREGEMIAREIIDLCGYR
Sbjct  61   LEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGYR  120

Query  121  GPIQRLWLSALNDASIRKALGALKPSAETLPLYFSALARSRADWLIGMNLSRLFTLLGRQ  180
            GPIQRLWLSALNDASIRKALGALKPS+E+LPLY +ALARSRADWL+GMNLSRLFTLLGRQ
Sbjct  121  GPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGRQ  180

Query  181  AGYSGVLSVGRVQTPTLKLVVDRDREIARFVCVPFWAIEVALSHAGQPFVASWTPPQGST  240
            AGY GVLSVGRVQTPTL LVV RDREIARFV VPFW+IEV+LS +G++F+A+W +++G +
Sbjct  181  AGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGCS  240

Query  241  DDAGRCLQQPvaqqaadriraardaqvvSVDTERVREAPPLPFDLGTLQEVCSKQLGLDV  300
            DDAGRCLQQ+ AQQAADR+R A  AQVV+V TERVREAPPLPFDLGTLQ+VCS+QL+LDV
Sbjct  241  DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALDV  300

Query  301  QETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLDALLATDPSLRPLIGQLDRNQ  360
            QETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVL A+L+TDPSLRPL+ QLDR Q
Sbjct  301  QETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRTQ  360

Query  361  RSRAWNDGKVSAHHGIIPTLEPANLSAMNEKELAVYRLIRAHYLAQFLPHHEFDRTVAQF  420
            RSRAWND+KVSAHHGIIPTLEPANL+A+++K LAVYRLIRAHYLAQFLPH EFDRT AQ+
Sbjct  361  RSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQL  420

Query  421  SCGSQSLAAVGKQIAVTGWREVLATPGPDDADGEDALRSQVLPALHAGLSCPVGKVDLKA  480
             CG+Q+L AVGKQ+ + GW++VLA P +D+ADGE   RSQVLPAL+ GLSC V  VDLKA
Sbjct  421  LCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLSCQVNHVDLKA  480

Query  481  LRTLPPKPYTQGELIKAMKTVAKFVTDPRLKQKLRDTTGIGTEATRANIINGLIGRGYLV  540
            L+T PPKPYTQG+LIKAMK VAK+VTDPRLKQKL++TTGIGTEATRA+II+GL+ RGYL+
Sbjct  481  LKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERGYLL  540

Query  541  KKGRAVRASDAAFTLIDAVPSAIADPGTTAVWEQALDMIEAGQMALDTFIEKQSVWVGQL  600
            KKGR+VRASDAA  LIDAVP+AI+DPGTTAVWEQALDMIEAG+M+L+TF+ KQS W+ QL
Sbjct  541  KKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWITQL  600

Query  601  VQQYRGATLSLKLPPTPACPQCGAPMQQRTGKSGAFWSCSRYPDCRGTLPIES  653
            VQQYR+ATL++KLP  PACP CG++ +QRTGK+G+FWSC RYPDC+GTLP+++
Sbjct  601  VQQYRAATLAIKLPEGPACPLCGSATRQRTGKTGPFWSCCRYPDCKGTLPVQN  653

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  872 bits (3304),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 504/653 (78%), Positives = 608/653 (94%), Gaps = 0/653 (0%)

Query  1    MRLFLCEKPSQGKDIGKVLGATQRDNGCLKGPGVIVTWCIGHLVEAAPPEAYDANLKHWS  60
            MRLFLCEKPSQGKDI++VLGA QR++GC +G+G +VTWCIGHL+EAAPPEAY+ + K+WS
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQYKRWS  60

Query  61   IEQLPIIPERWRIEVKPKTAAQFKVVKQLLAQATELVIATDADREGEMIAREIVELCGYR  120
            +EQLPIIPERWR+E K+ TAAQ+K+VKQL++QA+ELVIATDADREGEMIAREI++LCGYR
Sbjct  61   LEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGYR  120

Query  121  GPIQRLWLSALNDASIRKALAALKPSSETLPMYHSALARSRADWLVGMNLSRLFTLLGRQ  180
            GPIQRLWLSALNDASIRKAL+ALKPSSE+LP+Y +ALARSRADWLVGMNLSRLFTLLGRQ
Sbjct  121  GPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGRQ  180

Query  181  AGYDGVLSVGRVQTPTLKLVVDRDREINQFVSIPFWAIDVALSATGQSFIAQWLAPEACT  240
            AGYDGVLSVGRVQTPTL LVV RDREI +FVS+PFW+I+V+LS+ G+SF+A W+A+++C+
Sbjct  181  AGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGCS  240

Query  241  DEAGRCLQESVAQQAAQQLRANGTAQVASVETERVREGPPLPFDLGTLQEVCSKQLGLDV  300
            D+AGRCLQ++ AQQAA++LR  G+AQV +V TERVRE+PPLPFDLGTLQ+VCS+QL+LDV
Sbjct  241  DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALDV  300

Query  301  QETLDIAQALYETHKATTYPRSDSGYLPESMQADVPAVLDSLLRTDPALRPVMEQLDRRQ  360
            QETLDIAQALYETHKATTYPRSDSGYLPESM A+VPAVL ++L TDP+LRP++EQLDR Q
Sbjct  301  QETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRTQ  360

Query  361  RSRAWNDSKVTAHHGIIPTLEPANLSAMSEKELAVYRLIRAHYLAQFLPHHEFDRTIARL  420
            RSRAWNDSKV+AHHGIIPTLEPANL+A+S+K LAVYRLIRAHYLAQFLPH EFDRT A+L
Sbjct  361  RSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQL  420

Query  421  SCAGQHLQAVGKQIVIPGWRLVLVeqqaedaddeaaPRSQVLPALNQGLSCQMNTVDLKA  480
             C+GQ LQAVGKQ++IPGW+ VL   +A++AD+EA PRSQVLPAL +GLSCQ+N VDLKA
Sbjct  421  LCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLSCQVNHVDLKA  480

Query  481  LKTLPPRPYTQGELVKAMKSVAKLVSDPRLKQKLKDTVGIGTEATRANIINGLLTRGYLI  540
            LKT PP+PYTQG+L+KAMK+VAKLV+DPRLKQKLK+T GIGTEATRA+II+GLL RGYL+
Sbjct  481  LKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERGYLL  540

Query  541  KKGRAIRASEAAGTLIDTVPAAIADPGTTAVWEQALDMIEAGELTHDVFTGKQSAWISQI  600
            KKGR++RAS+AAG LID+VPAAI+DPGTTAVWEQALDMIEAG++T + F +KQS+WI+Q+
Sbjct  541  KKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWITQL  600

Query  601  IAQYQGTAMTIKVPQGPACPQCGSATRQRTGKNGPFWSCSRYPECKGTVPVDS  653
            + QY++++++IK+P+GPACP CGSATRQRTGK GPFWSC RYP+CKGT+PV++
Sbjct  601  VQQYRAATLAIKLPEGPACPLCGSATRQRTGKTGPFWSCCRYPDCKGTLPVQN  653

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  872 bits (3301),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 505/666 (76%), Positives = 610/666 (92%), Gaps = 4/666 (0%)

Query  1    MKLFLCEKPSQGKDIGRVLGATQRGKGCLTGSGITITWCIGHLVEAAPPDAYGEQYKRWS  60
            M+LFLCEKPSQGKDI+RVLGA QRG GC  G+G  +TWCIGHL+EAAPP+AYGEQYKRWS
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQYKRWS  60

Query  61   IEQLPIIPERWRVDVKSKTASQFNVVKDLLSKASELVIATDADREGELIAREIIELCGYR  120
            +EQLPIIPERWRV+ K+ TA+Q+++VK+L+++ASELVIATDADREGE+IAREII+LCGYR
Sbjct  61   LEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGYR  120

Query  121  GPIQRLWLSALNDASIRKALATLRPSSETLPMYFSALARSRADWLIGMNLSRLFTVMGRQ  180
            GPIQRLWLSALNDASIRKAL++L+PSSE+LP+Y +ALARSRADWL+GMNLSRLFT++GRQ
Sbjct  121  GPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGRQ  180

Query  181  AGYDGVLSVGRVQTPTLKLVVDRDREIACFVSVPFWAVETTLSSEGQSFTAAWLAPDTAT  240
            AGYDGVLSVGRVQTPTL LVV RDREIA FVSVPFW++E  LS+ G+SF A+W+A+D  +
Sbjct  181  AGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGCS  240

Query  241  DDAGRCLQESIARQAVERMRSAGSAQITSVETERMREGPPLPFDLGTLQEICSKQLGLDV  300
            DDAGRCLQ++ A+QA +R+R AGSAQ+ +V TER+RE+PPLPFDLGTLQ++CS+QL+LDV
Sbjct  241  DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALDV  300

Query  301  QETLEIAQALYETHKATTYPRSDSGYLPDSMFAEVPTVLDSLLKTDPGLRPLVDQLDRNQ  360
            QETL+IAQALYETHKATTYPRSDSGYLP+SM+AEVP+VL ++L TDP+LRPL++QLDR Q
Sbjct  301  QETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRTQ  360

Query  361  RSRAWNDSKVTAHHGIIPTLEPANLKAMNDKERAVYMLIRAHYLAQFLPQHEFDRTTARL  420
            RSRAWNDSKV+AHHGIIPTLEPANL A++DK  AVY LIRAHYLAQFLP+ EFDRTTA+L
Sbjct  361  RSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQL  420

Query  421  SCAGETLQAVGKQVVVIGWRQVLAEPRPDD-DGETTPRSQVLPALHEGLSCQITGIDCKA  479
             C+G+TLQAVGKQV++ GW+QVLA P +D+ DGE+ PRSQVLPAL+EGLSCQ+  +D KA
Sbjct  421  LCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLSCQVNHVDLKA  480

Query  480  LKTSPPRPYTQGELVKAMKGVAKLVADPRLKQKLKDTTGIGTEATRANIIKGLLDRGYLQ  539
            LKT PP+PYTQG+L+KAMKGVAKLV+DPRLKQKLK+TTGIGTEATRA+IIKGLL+RGYL 
Sbjct  481  LKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERGYLL  540

Query  540  KKGRSVRASDAAFTLIDVVPGAIADPGMTAIWEQALDMIEAGQLTLDVFIDKQSAWITQL  599
            KKGR+VRASDAA  LID VP+AI+DPG TA+WEQALDMIEAG++TL+ F+ KQS+WITQL
Sbjct  541  KKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWITQL  600

Query  600  VQQYQGASLSIKVPQGPACPECGTAMRQRTGKSGPFWSCPRYPDCKGSQPIDNGKH---K  656
            VQQY++A+L+IK+P+GPACP CG+A RQRTGK+GPFWSC RYPDCKG+ P++NG++   K
Sbjct  601  VQQYRAATLAIKLPEGPACPLCGSATRQRTGKTGPFWSCCRYPDCKGTLPVQNGRQASAK  660

Query  657  RAMPRK  662
            R+ +RK
Sbjct  661  RSTSRK  666

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  871 bits (3299),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 529/672 (79%), Positives = 614/672 (92%), Gaps = 3/672 (0%)

Query  1    MRVFLCEKPSQGKDIARVLGAGQRSNGCYSGAGVVVTWCIGHLVEAVPPEGYGEQYKRWA  60
            MR+FLCEKPSQGKDIARVLGAGQR++GCY+GAG VVTWCIGHL+EA PPE+YGEQYKRW+
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQYKRWS  60

Query  61   IEQLPIVPERWRVEPKVATAAQFKVVQQLVAKAGELVIATDADREGEMIAREIIDLCGYR  120
            +EQLPI+PERWRVEPK ATAAQ+K+V+QLV++A+ELVIATDADREGEMIAREIIDLCGYR
Sbjct  61   LEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGYR  120

Query  121  GPIQRLWLSALNDASIRKALGALKPSAETLPLYFSALARSRADWLIGMNLSRLFTLLGRQ  180
            GPIQRLWLSALNDASIRKALGALKPS+E+LPLY +ALARSRADWL+GMNLSRLFTLLGRQ
Sbjct  121  GPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGRQ  180

Query  181  AGYTGVLSVGRVQTPTLKLVVDRDREIARFVSVPYWAADVLLSHAGQSFTASWIPPEGST  240
            AGY GVLSVGRVQTPTL LVV RDREIARFVSVP+W+ +V LS +G+SF A+WI+++G +
Sbjct  181  AGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGCS  240

Query  241  DAAGRCLQQPVAQQAVDRIRAARDAQVVSVDTERVREAPPLPFDLGTLQEVCSRQLGLDV  300
            D AGRCLQQ+ AQQA DR+R A  AQVV+V TERVREAPPLPFDLGTLQ+VCSRQL+LDV
Sbjct  241  DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALDV  300

Query  301  QETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLDALLATEPSLRPLLGQLDRNQ  360
            QETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVL A+L+T+PSLRPLL QLDR Q
Sbjct  301  QETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRTQ  360

Query  361  RSRAWNDGKVTAHHGIIPTLEPAKLLAMSEKELAVYQLIRGRYLAQFLPHHEFDRTVTQL  420
            RSRAWND+KV+AHHGIIPTLEPA+L A+S+K LAVY+LIR++YLAQFLPH EFDRT +QL
Sbjct  361  RSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQL  420

Query  421  ACGGQSLVAVGKQIAVIGWRQVLATPEPDAADGEEAQRSQVLPPLASGSRCGVEQVELKA  480
             CGGQ+L AVGKQ+ + GW+QVLA PE+D ADGE   RSQVLP+L  G  C V++V+LKA
Sbjct  421  LCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLSCQVNHVDLKA  480

Query  481  LRTLPPKPYTQGELVKVMKGVAKLVDDPRLKQKLKETTGIGTEATRASTIKGLLDRGYLL  540
            L+T PPKPYTQG+L+K MKGVAKLV DPRLKQKLKETTGIGTEATRAS IKGLL+RGYLL
Sbjct  481  LKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERGYLL  540

Query  541  KKGRAIRASDAAFTLIDAVPAAIADPGMTAIWEQALDMIEAGQMTLDTFIAKQSTWVAQL  600
            KKGR++RASDAA  LIDAVPAAI+DPG TA+WEQALDMIEAG+MTL+TF+AKQSTW++QL
Sbjct  541  KKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWITQL  600

Query  601  VQQHRGATlsialppsppcpqcgapMRQRTGKSGAFWSCSRYPDCKGTLPVES---SASK  657
            VQQ R+ATL+I LP +P+CP CG++ RQRTGK+G+FWSC RYPDCKGTLPV++   +++K
Sbjct  601  VQQYRAATLAIKLPEGPACPLCGSATRQRTGKTGPFWSCCRYPDCKGTLPVQNGRQASAK  660

Query  658  RGAPRKRRTVPK  669
            R+++RK R +PK
Sbjct  661  RSTSRKPRQIPK  672

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  871 bits (3297),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 503/677 (75%), Positives = 615/677 (91%), Gaps = 8/677 (1%)

Query  1    MRLFLCEKPSQGKDIGRILGATQRGEGCLNGSGVTVTWCIGHLVEAAPPEAYDEQLKRWS  60
            MRLFLCEKPSQGKDI+R+LGA QRG GC NG+G  VTWCIGHL+EAAPPEAY+EQ KRWS
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQYKRWS  60

Query  61   VEQLPIIPQHWRVEVKPKTATQFKVVKALLAKATHLVIATDADREGELIAREIVELCGYR  120
            +EQLPIIP++WRVE K+ TA+Q+K+VK L+++A++LVIATDADREGE+IAREI++LCGYR
Sbjct  61   LEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGYR  120

Query  121  GPIERLWLSALNDASIRAALGKLRPSAETLSMYHSALARSRADWLVGMNLSRLFTVLGRQ  180
            GPI+RLWLSALNDASIR ALG L+PS+E+L++Y +ALARSRADWLVGMNLSRLFT+LGRQ
Sbjct  121  GPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGRQ  180

Query  181  AGYDGVLSVGRVQTPTLKLVVDRDREIARFVSVPYWAIAVSLFAGGSTFAAQWVPPDACT  240
            AGYDGVLSVGRVQTPTL LVV RDREIARFVSVP+W+I V+L +GG +F A W+++D+C+
Sbjct  181  AGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGCS  240

Query  241  DDAGRCLRQPVAQQTMQQIRAAGSAHVVSVETERVREGPPLPFDLGTLQEVCSKQLGLDV  300
            DDAGRCL+Q+ AQQ+ +++R AGSA+VV+V TERVRE+PPLPFDLGTLQ+VCS+QL+LDV
Sbjct  241  DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALDV  300

Query  301  QETLEIAQALYETHKATTYPRSDSGYLPESMFAEVPTVLDSLLKTDPSLRSIMGQLDRSQ  360
            QETL+IAQALYETHKATTYPRSDSGYLPESM+AEVP+VL ++L TDPSLR+++ QLDR+Q
Sbjct  301  QETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRTQ  360

Query  361  RSRAWNDGKVTAHHGIIPTLEPAKLSAMSEKELAVYRLIRSHYLAQFLPHHEFDRTVAKF  420
            RSRAWND+KV+AHHGIIPTLEPA+L+A+S+K LAVYRLIR+HYLAQFLPH EFDRT A++
Sbjct  361  RSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQL  420

Query  421  SCGGQNLAATGKQVVIPGWRQVLAEPQAEDGDGEGDTAVRAQVLPALPKLYEGLACQVAD  480
             CGGQ L A GKQV+IPGW+QVLA P+A+++DGE  +  R+QVLPAL    EGL+CQV +
Sbjct  421  LCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGE--AVPRSQVLPALR---EGLSCQVNH  475

Query  481  VDLKALKTLPPKPYTQGELVKSMKGVAKLVSDPRLKQKLKDTVGIGTEATRANIIGGLIA  540
            VDLKALKT PPKPYTQG+L+K+MKGVAKLV+DPRLKQKLK+T GIGTEATRA+II GL+ 
Sbjct  476  VDLKALKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLE  535

Query  541  RGYLVKKGRAIRASDAAFTLIDAVPAAIADPGTTAVWEQALDMIEAGQLTLDVFIGKQAA  600
            RGYL+KKGR++RASDAA  LIDAVPAAI+DPGTTAVWEQALDMIEAG++TL+ F++KQ++
Sbjct  536  RGYLLKKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQST  595

Query  601  WISQLIAQYGSASLSIKVPQGPACPQCGAPTRQRSGKSGPFWSCSRYPDCKGTLPVESG-  659
            WI+QL+ QY +A+L+IK+P+GPACP CG++TRQR+GK+GPFWSC RYPDCKGTLPV++G 
Sbjct  596  WITQLVQQYRAATLAIKLPEGPACPLCGSATRQRTGKTGPFWSCCRYPDCKGTLPVQNGR  655

Query  660  --SSKRGASRPRRSGRK  674
              S+KR++SR  R   K
Sbjct  656  QASAKRSTSRKPRQIPK  672

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  871 bits (3297),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 503/677 (75%), Positives = 615/677 (91%), Gaps = 8/677 (1%)

Query  1    MRLFLCEKPSQGKDIGRILGATQRGEGCLNGSGVTVTWCIGHLVEAAPPEAYDEQLKRWS  60
            MRLFLCEKPSQGKDI+R+LGA QRG GC NG+G  VTWCIGHL+EAAPPEAY+EQ KRWS
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQYKRWS  60

Query  61   VEQLPIIPQHWRVEVKPKTATQFKVVKALLAKATHLVIATDADREGELIAREIVELCGYR  120
            +EQLPIIP++WRVE K+ TA+Q+K+VK L+++A++LVIATDADREGE+IAREI++LCGYR
Sbjct  61   LEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGYR  120

Query  121  GPIERLWLSALNDASIRAALGKLRPSAETLSMYHSALARSRADWLVGMNLSRLFTVLGRQ  180
            GPI+RLWLSALNDASIR ALG L+PS+E+L++Y +ALARSRADWLVGMNLSRLFT+LGRQ
Sbjct  121  GPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGRQ  180

Query  181  AGYDGVLSVGRVQTPTLKLVVDRDREIARFVSVPYWAIAVSLFAGGSTFAAQWVPPDACT  240
            AGYDGVLSVGRVQTPTL LVV RDREIARFVSVP+W+I V+L +GG +F A W+++D+C+
Sbjct  181  AGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGCS  240

Query  241  DDAGRCLRQPVAQQTMQQIRAAGSAHVVSVETERVREGPPLPFDLGTLQEVCSKQLGLDV  300
            DDAGRCL+Q+ AQQ+ +++R AGSA+VV+V TERVRE+PPLPFDLGTLQ+VCS+QL+LDV
Sbjct  241  DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALDV  300

Query  301  QETLEIAQALYETHKATTYPRSDSGYLPESMFAEVPTVLDSLLKTDPSLRSIMGQLDRSQ  360
            QETL+IAQALYETHKATTYPRSDSGYLPESM+AEVP+VL ++L TDPSLR+++ QLDR+Q
Sbjct  301  QETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRTQ  360

Query  361  RSRAWNDGKVTAHHGIIPTLEPAKLSAMSEKELAVYRLIRSHYLAQFLPHHEFDRTVAKF  420
            RSRAWND+KV+AHHGIIPTLEPA+L+A+S+K LAVYRLIR+HYLAQFLPH EFDRT A++
Sbjct  361  RSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQL  420

Query  421  SCGGQNLAATGKQVVIPGWRQVLAEPQAEDGDGEGDTAVRAQVLPALPKLYEGLACQVAD  480
             CGGQ L A GKQV+IPGW+QVLA P+A+++DGE  +  R+QVLPAL    EGL+CQV +
Sbjct  421  LCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGE--AVPRSQVLPALR---EGLSCQVNH  475

Query  481  VDLKALKTLPPKPYTQGELVKSMKGVAKLVSDPRLKQKLKDTVGIGTEATRANIIGGLIA  540
            VDLKALKT PPKPYTQG+L+K+MKGVAKLV+DPRLKQKLK+T GIGTEATRA+II GL+ 
Sbjct  476  VDLKALKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLE  535

Query  541  RGYLVKKGRAIRASDAAFTLIDAVPAAIADPGTTAVWEQALDMIEAGQLTLDVFIGKQAA  600
            RGYL+KKGR++RASDAA  LIDAVPAAI+DPGTTAVWEQALDMIEAG++TL+ F++KQ++
Sbjct  536  RGYLLKKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQST  595

Query  601  WISQLIAQYGSASLSIKVPQGPACPQCGAPTRQRSGKSGPFWSCSRYPDCKGTLPVESG-  659
            WI+QL+ QY +A+L+IK+P+GPACP CG++TRQR+GK+GPFWSC RYPDCKGTLPV++G 
Sbjct  596  WITQLVQQYRAATLAIKLPEGPACPLCGSATRQRTGKTGPFWSCCRYPDCKGTLPVQNGR  655

Query  660  --SSKRGASRPRRSGRK  674
              S+KR++SR  R   K
Sbjct  656  QASAKRSTSRKPRQIPK  672

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  871 bits (3297),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 503/677 (75%), Positives = 615/677 (91%), Gaps = 8/677 (1%)

Query  1    MRLFLCEKPSQGKDIGRILGATQRGEGCLNGSGVTVTWCIGHLVEAAPPEAYDEQLKRWS  60
            MRLFLCEKPSQGKDI+R+LGA QRG GC NG+G  VTWCIGHL+EAAPPEAY+EQ KRWS
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQYKRWS  60

Query  61   VEQLPIIPQHWRVEVKPKTATQFKVVKALLAKATHLVIATDADREGELIAREIVELCGYR  120
            +EQLPIIP++WRVE K+ TA+Q+K+VK L+++A++LVIATDADREGE+IAREI++LCGYR
Sbjct  61   LEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGYR  120

Query  121  GPIERLWLSALNDASIRAALGKLRPSAETLSMYHSALARSRADWLVGMNLSRLFTVLGRQ  180
            GPI+RLWLSALNDASIR ALG L+PS+E+L++Y +ALARSRADWLVGMNLSRLFT+LGRQ
Sbjct  121  GPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGRQ  180

Query  181  AGYDGVLSVGRVQTPTLKLVVDRDREIARFVSVPYWAIAVSLFAGGSTFAAQWVPPDACT  240
            AGYDGVLSVGRVQTPTL LVV RDREIARFVSVP+W+I V+L +GG +F A W+++D+C+
Sbjct  181  AGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGCS  240

Query  241  DDAGRCLRQPVAQQTMQQIRAAGSAHVVSVETERVREGPPLPFDLGTLQEVCSKQLGLDV  300
            DDAGRCL+Q+ AQQ+ +++R AGSA+VV+V TERVRE+PPLPFDLGTLQ+VCS+QL+LDV
Sbjct  241  DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALDV  300

Query  301  QETLEIAQALYETHKATTYPRSDSGYLPESMFAEVPTVLDSLLKTDPSLRSIMGQLDRSQ  360
            QETL+IAQALYETHKATTYPRSDSGYLPESM+AEVP+VL ++L TDPSLR+++ QLDR+Q
Sbjct  301  QETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRTQ  360

Query  361  RSRAWNDGKVTAHHGIIPTLEPAKLSAMSEKELAVYRLIRSHYLAQFLPHHEFDRTVAKF  420
            RSRAWND+KV+AHHGIIPTLEPA+L+A+S+K LAVYRLIR+HYLAQFLPH EFDRT A++
Sbjct  361  RSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQL  420

Query  421  SCGGQNLAATGKQVVIPGWRQVLAEPQAEDGDGEGDTAVRAQVLPALPKLYEGLACQVAD  480
             CGGQ L A GKQV+IPGW+QVLA P+A+++DGE  +  R+QVLPAL    EGL+CQV +
Sbjct  421  LCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGE--AVPRSQVLPALR---EGLSCQVNH  475

Query  481  VDLKALKTLPPKPYTQGELVKSMKGVAKLVSDPRLKQKLKDTVGIGTEATRANIIGGLIA  540
            VDLKALKT PPKPYTQG+L+K+MKGVAKLV+DPRLKQKLK+T GIGTEATRA+II GL+ 
Sbjct  476  VDLKALKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLE  535

Query  541  RGYLVKKGRAIRASDAAFTLIDAVPAAIADPGTTAVWEQALDMIEAGQLTLDVFIGKQAA  600
            RGYL+KKGR++RASDAA  LIDAVPAAI+DPGTTAVWEQALDMIEAG++TL+ F++KQ++
Sbjct  536  RGYLLKKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQST  595

Query  601  WISQLIAQYGSASLSIKVPQGPACPQCGAPTRQRSGKSGPFWSCSRYPDCKGTLPVESG-  659
            WI+QL+ QY +A+L+IK+P+GPACP CG++TRQR+GK+GPFWSC RYPDCKGTLPV++G 
Sbjct  596  WITQLVQQYRAATLAIKLPEGPACPLCGSATRQRTGKTGPFWSCCRYPDCKGTLPVQNGR  655

Query  660  --SSKRGASRPRRSGRK  674
              S+KR++SR  R   K
Sbjct  656  QASAKRSTSRKPRQIPK  672

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  871 bits (3297),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 503/677 (75%), Positives = 615/677 (91%), Gaps = 8/677 (1%)

Query  1    MRLFLCEKPSQGKDIGRILGATQRGEGCLNGSGVTVTWCIGHLVEAAPPEAYDEQLKRWS  60
            MRLFLCEKPSQGKDI+R+LGA QRG GC NG+G  VTWCIGHL+EAAPPEAY+EQ KRWS
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQYKRWS  60

Query  61   VEQLPIIPQHWRVEVKPKTATQFKVVKALLAKATHLVIATDADREGELIAREIVELCGYR  120
            +EQLPIIP++WRVE K+ TA+Q+K+VK L+++A++LVIATDADREGE+IAREI++LCGYR
Sbjct  61   LEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGYR  120

Query  121  GPIERLWLSALNDASIRAALGKLRPSAETLSMYHSALARSRADWLVGMNLSRLFTVLGRQ  180
            GPI+RLWLSALNDASIR ALG L+PS+E+L++Y +ALARSRADWLVGMNLSRLFT+LGRQ
Sbjct  121  GPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGRQ  180

Query  181  AGYDGVLSVGRVQTPTLKLVVDRDREIARFVSVPYWAIAVSLFAGGSTFAAQWVPPDACT  240
            AGYDGVLSVGRVQTPTL LVV RDREIARFVSVP+W+I V+L +GG +F A W+++D+C+
Sbjct  181  AGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGCS  240

Query  241  DDAGRCLRQPVAQQTMQQIRAAGSAHVVSVETERVREGPPLPFDLGTLQEVCSKQLGLDV  300
            DDAGRCL+Q+ AQQ+ +++R AGSA+VV+V TERVRE+PPLPFDLGTLQ+VCS+QL+LDV
Sbjct  241  DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALDV  300

Query  301  QETLEIAQALYETHKATTYPRSDSGYLPESMFAEVPTVLDSLLKTDPSLRSIMGQLDRSQ  360
            QETL+IAQALYETHKATTYPRSDSGYLPESM+AEVP+VL ++L TDPSLR+++ QLDR+Q
Sbjct  301  QETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRTQ  360

Query  361  RSRAWNDGKVTAHHGIIPTLEPAKLSAMSEKELAVYRLIRSHYLAQFLPHHEFDRTVAKF  420
            RSRAWND+KV+AHHGIIPTLEPA+L+A+S+K LAVYRLIR+HYLAQFLPH EFDRT A++
Sbjct  361  RSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQL  420

Query  421  SCGGQNLAATGKQVVIPGWRQVLAEPQAEDGDGEGDTAVRAQVLPALPKLYEGLACQVAD  480
             CGGQ L A GKQV+IPGW+QVLA P+A+++DGE  +  R+QVLPAL    EGL+CQV +
Sbjct  421  LCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGE--AVPRSQVLPALR---EGLSCQVNH  475

Query  481  VDLKALKTLPPKPYTQGELVKSMKGVAKLVSDPRLKQKLKDTVGIGTEATRANIIGGLIA  540
            VDLKALKT PPKPYTQG+L+K+MKGVAKLV+DPRLKQKLK+T GIGTEATRA+II GL+ 
Sbjct  476  VDLKALKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLE  535

Query  541  RGYLVKKGRAIRASDAAFTLIDAVPAAIADPGTTAVWEQALDMIEAGQLTLDVFIGKQAA  600
            RGYL+KKGR++RASDAA  LIDAVPAAI+DPGTTAVWEQALDMIEAG++TL+ F++KQ++
Sbjct  536  RGYLLKKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQST  595

Query  601  WISQLIAQYGSASLSIKVPQGPACPQCGAPTRQRSGKSGPFWSCSRYPDCKGTLPVESG-  659
            WI+QL+ QY +A+L+IK+P+GPACP CG++TRQR+GK+GPFWSC RYPDCKGTLPV++G 
Sbjct  596  WITQLVQQYRAATLAIKLPEGPACPLCGSATRQRTGKTGPFWSCCRYPDCKGTLPVQNGR  655

Query  660  --SSKRGASRPRRSGRK  674
              S+KR++SR  R   K
Sbjct  656  QASAKRSTSRKPRQIPK  672

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  871 bits (3297),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 503/677 (75%), Positives = 615/677 (91%), Gaps = 8/677 (1%)

Query  1    MRLFLCEKPSQGKDIGRILGATQRGEGCLNGSGVTVTWCIGHLVEAAPPEAYDEQLKRWS  60
            MRLFLCEKPSQGKDI+R+LGA QRG GC NG+G  VTWCIGHL+EAAPPEAY+EQ KRWS
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQYKRWS  60

Query  61   VEQLPIIPQHWRVEVKPKTATQFKVVKALLAKATHLVIATDADREGELIAREIVELCGYR  120
            +EQLPIIP++WRVE K+ TA+Q+K+VK L+++A++LVIATDADREGE+IAREI++LCGYR
Sbjct  61   LEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGYR  120

Query  121  GPIERLWLSALNDASIRAALGKLRPSAETLSMYHSALARSRADWLVGMNLSRLFTVLGRQ  180
            GPI+RLWLSALNDASIR ALG L+PS+E+L++Y +ALARSRADWLVGMNLSRLFT+LGRQ
Sbjct  121  GPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGRQ  180

Query  181  AGYDGVLSVGRVQTPTLKLVVDRDREIARFVSVPYWAIAVSLFAGGSTFAAQWVPPDACT  240
            AGYDGVLSVGRVQTPTL LVV RDREIARFVSVP+W+I V+L +GG +F A W+++D+C+
Sbjct  181  AGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGCS  240

Query  241  DDAGRCLRQPVAQQTMQQIRAAGSAHVVSVETERVREGPPLPFDLGTLQEVCSKQLGLDV  300
            DDAGRCL+Q+ AQQ+ +++R AGSA+VV+V TERVRE+PPLPFDLGTLQ+VCS+QL+LDV
Sbjct  241  DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALDV  300

Query  301  QETLEIAQALYETHKATTYPRSDSGYLPESMFAEVPTVLDSLLKTDPSLRSIMGQLDRSQ  360
            QETL+IAQALYETHKATTYPRSDSGYLPESM+AEVP+VL ++L TDPSLR+++ QLDR+Q
Sbjct  301  QETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRTQ  360

Query  361  RSRAWNDGKVTAHHGIIPTLEPAKLSAMSEKELAVYRLIRSHYLAQFLPHHEFDRTVAKF  420
            RSRAWND+KV+AHHGIIPTLEPA+L+A+S+K LAVYRLIR+HYLAQFLPH EFDRT A++
Sbjct  361  RSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQL  420

Query  421  SCGGQNLAATGKQVVIPGWRQVLAEPQAEDGDGEGDTAVRAQVLPALPKLYEGLACQVAD  480
             CGGQ L A GKQV+IPGW+QVLA P+A+++DGE  +  R+QVLPAL    EGL+CQV +
Sbjct  421  LCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGE--AVPRSQVLPALR---EGLSCQVNH  475

Query  481  VDLKALKTLPPKPYTQGELVKSMKGVAKLVSDPRLKQKLKDTVGIGTEATRANIIGGLIA  540
            VDLKALKT PPKPYTQG+L+K+MKGVAKLV+DPRLKQKLK+T GIGTEATRA+II GL+ 
Sbjct  476  VDLKALKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLE  535

Query  541  RGYLVKKGRAIRASDAAFTLIDAVPAAIADPGTTAVWEQALDMIEAGQLTLDVFIGKQAA  600
            RGYL+KKGR++RASDAA  LIDAVPAAI+DPGTTAVWEQALDMIEAG++TL+ F++KQ++
Sbjct  536  RGYLLKKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQST  595

Query  601  WISQLIAQYGSASLSIKVPQGPACPQCGAPTRQRSGKSGPFWSCSRYPDCKGTLPVESG-  659
            WI+QL+ QY +A+L+IK+P+GPACP CG++TRQR+GK+GPFWSC RYPDCKGTLPV++G 
Sbjct  596  WITQLVQQYRAATLAIKLPEGPACPLCGSATRQRTGKTGPFWSCCRYPDCKGTLPVQNGR  655

Query  660  --SSKRGASRPRRSGRK  674
              S+KR++SR  R   K
Sbjct  656  QASAKRSTSRKPRQIPK  672

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  871 bits (3297),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 503/677 (75%), Positives = 615/677 (91%), Gaps = 8/677 (1%)

Query  1    MRLFLCEKPSQGKDIGRILGATQRGEGCLNGSGVTVTWCIGHLVEAAPPEAYDEQLKRWS  60
            MRLFLCEKPSQGKDI+R+LGA QRG GC NG+G  VTWCIGHL+EAAPPEAY+EQ KRWS
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQYKRWS  60

Query  61   VEQLPIIPQHWRVEVKPKTATQFKVVKALLAKATHLVIATDADREGELIAREIVELCGYR  120
            +EQLPIIP++WRVE K+ TA+Q+K+VK L+++A++LVIATDADREGE+IAREI++LCGYR
Sbjct  61   LEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGYR  120

Query  121  GPIERLWLSALNDASIRAALGKLRPSAETLSMYHSALARSRADWLVGMNLSRLFTVLGRQ  180
            GPI+RLWLSALNDASIR ALG L+PS+E+L++Y +ALARSRADWLVGMNLSRLFT+LGRQ
Sbjct  121  GPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGRQ  180

Query  181  AGYDGVLSVGRVQTPTLKLVVDRDREIARFVSVPYWAIAVSLFAGGSTFAAQWVPPDACT  240
            AGYDGVLSVGRVQTPTL LVV RDREIARFVSVP+W+I V+L +GG +F A W+++D+C+
Sbjct  181  AGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGCS  240

Query  241  DDAGRCLRQPVAQQTMQQIRAAGSAHVVSVETERVREGPPLPFDLGTLQEVCSKQLGLDV  300
            DDAGRCL+Q+ AQQ+ +++R AGSA+VV+V TERVRE+PPLPFDLGTLQ+VCS+QL+LDV
Sbjct  241  DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALDV  300

Query  301  QETLEIAQALYETHKATTYPRSDSGYLPESMFAEVPTVLDSLLKTDPSLRSIMGQLDRSQ  360
            QETL+IAQALYETHKATTYPRSDSGYLPESM+AEVP+VL ++L TDPSLR+++ QLDR+Q
Sbjct  301  QETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRTQ  360

Query  361  RSRAWNDGKVTAHHGIIPTLEPAKLSAMSEKELAVYRLIRSHYLAQFLPHHEFDRTVAKF  420
            RSRAWND+KV+AHHGIIPTLEPA+L+A+S+K LAVYRLIR+HYLAQFLPH EFDRT A++
Sbjct  361  RSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQL  420

Query  421  SCGGQNLAATGKQVVIPGWRQVLAEPQAEDGDGEGDTAVRAQVLPALPKLYEGLACQVAD  480
             CGGQ L A GKQV+IPGW+QVLA P+A+++DGE  +  R+QVLPAL    EGL+CQV +
Sbjct  421  LCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGE--AVPRSQVLPALR---EGLSCQVNH  475

Query  481  VDLKALKTLPPKPYTQGELVKSMKGVAKLVSDPRLKQKLKDTVGIGTEATRANIIGGLIA  540
            VDLKALKT PPKPYTQG+L+K+MKGVAKLV+DPRLKQKLK+T GIGTEATRA+II GL+ 
Sbjct  476  VDLKALKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLE  535

Query  541  RGYLVKKGRAIRASDAAFTLIDAVPAAIADPGTTAVWEQALDMIEAGQLTLDVFIGKQAA  600
            RGYL+KKGR++RASDAA  LIDAVPAAI+DPGTTAVWEQALDMIEAG++TL+ F++KQ++
Sbjct  536  RGYLLKKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQST  595

Query  601  WISQLIAQYGSASLSIKVPQGPACPQCGAPTRQRSGKSGPFWSCSRYPDCKGTLPVESG-  659
            WI+QL+ QY +A+L+IK+P+GPACP CG++TRQR+GK+GPFWSC RYPDCKGTLPV++G 
Sbjct  596  WITQLVQQYRAATLAIKLPEGPACPLCGSATRQRTGKTGPFWSCCRYPDCKGTLPVQNGR  655

Query  660  --SSKRGASRPRRSGRK  674
              S+KR++SR  R   K
Sbjct  656  QASAKRSTSRKPRQIPK  672

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  871 bits (3299),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 503/677 (75%), Positives = 615/677 (91%), Gaps = 8/677 (1%)

Query  1    MRLFLCEKPSQGKDIGRILGATQRGEGCLNGSGVTVTWCIGHLVEAAPPEAYDEQLKRWS  60
            MRLFLCEKPSQGKDI+R+LGA QRG GC NG+G  VTWCIGHL+EAAPPEAY+EQ KRWS
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQYKRWS  60

Query  61   VEQLPIIPQHWRVEVKPKTATQFKVVKALLAKATHLVIATDADREGELIAREIVELCGYR  120
            +EQLPIIP++WRVE K+ TA+Q+K+VK L+++A++LVIATDADREGE+IAREI++LCGYR
Sbjct  61   LEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGYR  120

Query  121  GPIERLWLSALNDASIRAALGQLRPSAETLSMYHSALARSRADWLVGMNLSRLFTVLGRQ  180
            GPI+RLWLSALNDASIR ALG L+PS+E+L++Y +ALARSRADWLVGMNLSRLFT+LGRQ
Sbjct  121  GPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGRQ  180

Query  181  AGYDGVLSVGRVQTPTLKLVVDRDREIARFVSVPYWAIAVSLFAGGSTFAAQWVPPDACT  240
            AGYDGVLSVGRVQTPTL LVV RDREIARFVSVP+W+I V+L +GG +F A W+++D+C+
Sbjct  181  AGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGCS  240

Query  241  DDAGRCLRQPVAQQTMQQIRAAGSAHVVSVETERVREGPPLPFDLGTLQEVCSKQLGLDV  300
            DDAGRCL+Q+ AQQ+ +++R AGSA+VV+V TERVRE+PPLPFDLGTLQ+VCS+QL+LDV
Sbjct  241  DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALDV  300

Query  301  QETLEIAQALYETHKATTYPRSDSGYLPESMFAEVPTVLDSLLKTDPSLRSIMGQLDRSQ  360
            QETL+IAQALYETHKATTYPRSDSGYLPESM+AEVP+VL ++L TDPSLR+++ QLDR+Q
Sbjct  301  QETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRTQ  360

Query  361  RSRAWNDGKVTAHHGIIPTLEPAKLSAMSEKELAVYRLIRSHYLAQFLPHHEFDRTVAKF  420
            RSRAWND+KV+AHHGIIPTLEPA+L+A+S+K LAVYRLIR+HYLAQFLPH EFDRT A++
Sbjct  361  RSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQL  420

Query  421  SCGGQNLAATGKQVVIPGWRQVLAEPQAEDGDGEGDTAVRAQVLPALPKLYEGLACQVAD  480
             CGGQ L A GKQV+IPGW+QVLA P+A+++DGE  +  R+QVLPAL    EGL+CQV +
Sbjct  421  LCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGE--AVPRSQVLPALR---EGLSCQVNH  475

Query  481  VDLKALKTLPPKPYTQGELVKSMKGVAKLVSDPRLKQKLKDTVGIGTEATRANIIGGLIA  540
            VDLKALKT PPKPYTQG+L+K+MKGVAKLV+DPRLKQKLK+T GIGTEATRA+II GL+ 
Sbjct  476  VDLKALKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLE  535

Query  541  RGYLVKKGRAIRASDAAFTLIDAVPAAIADPGTTAVWEQALDMIEAGQLTLDVFIGKQAA  600
            RGYL+KKGR++RASDAA  LIDAVPAAI+DPGTTAVWEQALDMIEAG++TL+ F++KQ++
Sbjct  536  RGYLLKKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQST  595

Query  601  WISQLIAQYGSASLSIKVPQGPACPQCGAPTRQRSGKSGPFWSCSRYPDCKGTLPVESG-  659
            WI+QL+ QY +A+L+IK+P+GPACP CG++TRQR+GK+GPFWSC RYPDCKGTLPV++G 
Sbjct  596  WITQLVQQYRAATLAIKLPEGPACPLCGSATRQRTGKTGPFWSCCRYPDCKGTLPVQNGR  655

Query  660  --SSKRGASRPRRSGRK  674
              S+KR++SR  R   K
Sbjct  656  QASAKRSTSRKPRQIPK  672

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  867 bits (3285),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 518/653 (80%), Positives = 607/653 (93%), Gaps = 0/653 (0%)

Query  1    MRVFLCEKPSQGKDIARVLGAGQRGNGCYSGAGVVVTWCIGHLVEAVPPEGYGEQYKRWA  60
            MR+FLCEKPSQGKDIARVLGAGQRG+GCY+GAG VVTWCIGHL+EA PPE+YGEQYKRW+
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQYKRWS  60

Query  61   IEQLPILPERWRVEPKSATAAQFKVVQQLVAKAGELVIATDADREGEMIAREIIDLCSYR  120
            +EQLPI+PERWRVEPK+ATAAQ+K+V+QLV++A+ELVIATDADREGEMIAREIIDLC+YR
Sbjct  61   LEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGYR  120

Query  121  GPIQRLWLSALNDVSIRKALGALKPSAETLPLYFSALARSRADWLIGMNLSRLFTLLGRQ  180
            GPIQRLWLSALND SIRKALGALKPS+E+LPLY +ALARSRADWL+GMNLSRLFTLLGRQ
Sbjct  121  GPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGRQ  180

Query  181  AGYTGVLSVGRVQTPTLKLVVDRDREIARFVCVPFWAIEVALSHAGQSFVASWTPPQGST  240
            AGY GVLSVGRVQTPTL LVV RDREIARFV VPFW+IEV+LS +G+SF+A+W +++G +
Sbjct  181  AGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGCS  240

Query  241  DDAGRCLQQPVAQQAVERLRTAGAAQVRSVETERVREGPPLPFDLGTLQEVCSKQLGLDV  300
            DDAGRCLQQ+ AQQA +RLR AG+AQV +V TERVRE+PPLPFDLGTLQ+VCS+QL+LDV
Sbjct  241  DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALDV  300

Query  301  QETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPTVLDSMVKTDPSLRPLIERLDRQQ  360
            QETLDIAQALYETHKATTYPRSDSGYLPESMLAEVP+VL +M+ TDPSLRPL+E+LDR Q
Sbjct  301  QETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRTQ  360

Query  361  RSRAWNDGKVSAHHGIIPTLEPANLSAMNEKELAVYRLIRAHYLAQFLPHHEFDRTVAQF  420
            RSRAWND+KVSAHHGIIPTLEPANL+A+++K LAVYRLIRAHYLAQFLPH EFDRT AQ+
Sbjct  361  RSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQL  420

Query  421  SCGSQSLAAVGKQIAVIGWREVLATPGPDDADGEDAQRSQVLPALHAGLSCPVGKVDLKA  480
             CG+Q+L AVGKQ+ + GW++VLA P +D+ADGE   RSQVLPAL+ GLSC V  VDLKA
Sbjct  421  LCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLSCQVNHVDLKA  480

Query  481  LKTLPPKPYTQGELIKAMKTVAKFVTDPRLKQKLRDTTGIGTEATRANIINGLIGRGYLV  540
            LKT PPKPYTQG+LIKAMK VAK+VTDPRLKQKL++TTGIGTEATRA+II+GL+ RGYL+
Sbjct  481  LKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERGYLL  540

Query  541  KKGRAVRASDAAFTLIDAVPSAIADPGTTAVWEHALDMIEAGQMALDTFIEKQAAWVGQL  600
            KKGR+VRASDAA  LIDAVP+AI+DPGTTAVWE+ALDMIEAG+M+L+TF+ KQ++W+ QL
Sbjct  541  KKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWITQL  600

Query  601  VQQYRGATLSLKLppapacpqcgapmqqRTGKSGAFWSCSRYPDCKGTLPIES  653
            VQQYR+ATL++KLP +PACP CG++ +QRTGK+G+FWSC RYPDCKGTLP+++
Sbjct  601  VQQYRAATLAIKLPEGPACPLCGSATRQRTGKTGPFWSCCRYPDCKGTLPVQN  653

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  866 bits (3281),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 522/653 (80%), Positives = 607/653 (93%), Gaps = 0/653 (0%)

Query  1    MRVFLCEKPSQGKDIARVLGAGQRGNGCYSGAGVVVTWCIGHLVEAVPPEGYGEQYKRWA  60
            MR+FLCEKPSQGKDIARVLGAGQRG+GCY+GAG VVTWCIGHL+EA PPE+YGEQYKRW+
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQYKRWS  60

Query  61   IEQLPILPERWRVEPKAATAAQFKVVQQLVAKAGELVIATDADREGEMIAREIIDLCGYR  120
            +EQLPI+PERWRVEPKAATAAQ+K+V+QLV++A+ELVIATDADREGEMIAREIIDLCGYR
Sbjct  61   LEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGYR  120

Query  121  GPIQRLWLSALNDASIRKALGALKPSDETLPLYFSALARSRADWLIGMNLSRLFTLLGRQ  180
            GPIQRLWLSALNDASIRKALGALKPS E+LPLY +ALARSRADWL+GMNLSRLFTLLGRQ
Sbjct  121  GPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGRQ  180

Query  181  AGYTGVLSVGRVQTPTLKLVVDRDREIARFVCVPFWAIEVALSHAGQSFVASWTPPQGSA  240
            AGY GVLSVGRVQTPTL LVV RDREIARFV VPFW+IEV+LS +G+SF+A+W +++G +
Sbjct  181  AGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGCS  240

Query  241  DDADRCLQQPVAQQAAEFLRAAGTAQVLSVETERVREGPPLPFDLGTLQEVCSKQLGLDV  300
            DDA+RCLQQ+ AQQAA+ LR AG+AQV++V TERVRE+PPLPFDLGTLQ+VCS+QL+LDV
Sbjct  241  DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALDV  300

Query  301  QETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPTVLNSLVKTDPSLRPLIERLDRQQ  360
            QETLDIAQALYETHKATTYPRSDSGYLPESMLAEVP+VL +++ TDPSLRPL+E+LDR Q
Sbjct  301  QETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRTQ  360

Query  361  RSRAWNDGKVSAHHGIIPTLEPANLSAMNEKELAVYRLIRAHYLAQFLPHHEFDRTVAQF  420
            RSRAWND+KVSAHHGIIPTLEPANL+A+++K LAVYRLIRAHYLAQFLPH EFDRT AQ+
Sbjct  361  RSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQL  420

Query  421  SCGSQSLAAVGKQIAVIGWREVLATPGPDDADGEDAQRSQVLPALHAGLSCPVGKVDLKA  480
             CG+Q+L AVGKQ+ + GW++VLA P +D+ADGE   RSQVLPAL+ GLSC V  VDLKA
Sbjct  421  LCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLSCQVNHVDLKA  480

Query  481  LKTLPPKPYTQGELIKAMKTVAKLVTDPRLKQKLRDTTGIGTEATRANIINGLIGRGYLV  540
            LKT PPKPYTQG+LIKAMK VAKLVTDPRLKQKL++TTGIGTEATRA+II+GL+ RGYL+
Sbjct  481  LKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERGYLL  540

Query  541  KKGRAVRASDAAFTLIDAVPSAIADPGTTAVWEQALDMIEAGQMTLDTFIEKQSVWVGQL  600
            KKGR+VRASDAA  LIDAVP+AI+DPGTTAVWEQALDMIEAG+MTL+TF+ KQS W+ QL
Sbjct  541  KKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWITQL  600

Query  601  VQQYRGATLSLKLppapacpqcaapmqqRTGKSGAFWSCSRYPDCKGTLPIES  653
            VQQYR+ATL++KLP +PACP C+++ +QRTGK+G+FWSC RYPDCKGTLP+++
Sbjct  601  VQQYRAATLAIKLPEGPACPLCGSATRQRTGKTGPFWSCCRYPDCKGTLPVQN  653

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  864 bits (3272),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 523/666 (79%), Positives = 614/666 (93%), Gaps = 3/666 (0%)

Query  1    MRVFLCEKPSQGKDIARVLGAGHRGNGCYSGAGVVVTWCIGHLVEAVPPEGYGDQYKRWA  60
            MR+FLCEKPSQGKDIARVLGAG+RG+GCY+GAG VVTWCIGHL+EA PPE+YG+QYKRW+
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQYKRWS  60

Query  61   IEQLPILPERWRVEPKAATAAQFKVVQQLVAKAGELVIATDADREGEMIAREIIDLCGYH  120
            +EQLPI+PERWRVEPKAATAAQ+K+V+QLV++A+ELVIATDADREGEMIAREIIDLCGY+
Sbjct  61   LEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGYR  120

Query  121  GPIQRLWLSALNDASIRKALGALKPSAETLPLYFSALARSRADWLIGMNLSRLFTLLGRQ  180
            GPIQRLWLSALNDASIRKALGALKPS+E+LPLY +ALARSRADWL+GMNLSRLFTLLGRQ
Sbjct  121  GPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGRQ  180

Query  181  AGYMGVLSVGRVQTPTLKLVVDRDREIARFVSVPYWAVDVLLSHAGRSFTASWIPPEGST  240
            AGY GVLSVGRVQTPTL LVV RDREIARFVSVP+W+++V LS +G+SF A+WI+++G +
Sbjct  181  AGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGCS  240

Query  241  DAAGRCLQQPVAQQAADCIRAARDAQVVSVDTERVREAPPLPFDLGTLQEVCSKQLGLDV  300
            D AGRCLQQ+ AQQAAD +R A  AQVV+V TERVREAPPLPFDLGTLQ+VCS+QL+LDV
Sbjct  241  DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALDV  300

Query  301  QETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLDALLATDPSLRPLIGQLDRNQ  360
            QETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVL A+L+TDPSLRPL+ QLDR Q
Sbjct  301  QETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRTQ  360

Query  361  RSRAWNDGKVTAHHGIIPTLEPANLSAMNEKELAVYRLIRAHYLAQFLPHHEFDRTVAQF  420
            RSRAWND+KV+AHHGIIPTLEPANL+A+++K LAVYRLIRAHYLAQFLPH EFDRT AQ+
Sbjct  361  RSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQL  420

Query  421  SCGSQSLAAVGKQIAVTGWREVLATPGPDDADGEDAQRSQVLPALHAGLSCPVGKVDLKA  480
             CG+Q+L AVGKQ+ + GW++VLA P +D+ADGE   RSQVLPAL+ GLSC V  VDLKA
Sbjct  421  LCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLSCQVNHVDLKA  480

Query  481  LKTLPPKPYTQGELIKAMKTVAKFVTDPRLKQKLRDTTGIGTEATRANTINGLIGRGYLV  540
            LKT PPKPYTQG+LIKAMK VAK+VTDPRLKQKL++TTGIGTEATRA+ I+GL+ RGYL+
Sbjct  481  LKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERGYLL  540

Query  541  KKGRAVRASDAAFTLIDAVPSAIADPGTTAVWEQALDMIEAGQMALDTFIEKQSVWVGQL  600
            KKGR+VRASDAA  LIDAVP+AI+DPGTTAVWEQALDMIEAG+M+L+TF+ KQS W+ QL
Sbjct  541  KKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWITQL  600

Query  601  VQQYRGATLSLKLppapacpqcgapmqqRTGKSGAFWSCSRYPDCKGTLPIES---PTGR  657
            VQQYR+ATL++KLP +PACP CG++ +QRTGK+G+FWSC RYPDCKGTLP+++   ++++
Sbjct  601  VQQYRAATLAIKLPEGPACPLCGSATRQRTGKTGPFWSCCRYPDCKGTLPVQNGRQASAK  660

Query  658  RSAPRK  663
            RS++RK
Sbjct  661  RSTSRK  666

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  864 bits (3273),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 503/668 (76%), Positives = 613/668 (92%), Gaps = 4/668 (0%)

Query  1    MCEKPSQGKDIGRVLGATQRGNGCLAGSGITVTWCIGHLVEAAPPETYGEQYKRWSIEQL  60
            +CEKPSQGKDI+RVLGA QRG+GC  G+G  VTWCIGHL+EAAPPE+YGEQYKRWS+EQL
Sbjct  5    LCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQYKRWSLEQL  64

Query  61   PIIPERWRVEVKSKTASQFNVVKNLLSKATELVIATDADREGELIAREIIELCGYHGPIQ  120
            PIIPERWRVE K+ TA+Q+++VK+L+++A+ELVIATDADREGE+IAREII+LCGY+GPIQ
Sbjct  65   PIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGYRGPIQ  124

Query  121  RLWLSALNDASIRKALAALRPSGETLPMYFSALARSRADWLIGMNLSRLFTVMGRQAGYD  180
            RLWLSALNDASIRKAL+AL+PS+E+LP+Y +ALARSRADWL+GMNLSRLFT++GRQAGYD
Sbjct  125  RLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGRQAGYD  184

Query  181  GVLSVGRVQTPTLKLVVDRDREIARFVSVPFWTVETVLSSAGQSFTAGWLAPDTATDDAG  240
            GVLSVGRVQTPTL LVV RDREIARFVSVPFW++E  LS++G+SF A W+A+D  +DDAG
Sbjct  185  GVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGCSDDAG  244

Query  241  RCLQEPIARQAAERMRIAGSAQVTSVETERLREGPPLPFDLGTLQEICSKQLGLDVQETL  300
            RCLQ++ A+QAA+R+R+AGSAQV +V TER+RE+PPLPFDLGTLQ++CS+QL+LDVQETL
Sbjct  245  RCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALDVQETL  304

Query  301  EIAQALYETHKATTYPRSDSGYLPESMFAEVPVVLDSLLKTDPGLRPIVDQLDRNQRSRA  360
            +IAQALYETHKATTYPRSDSGYLPESM+AEVP VL ++L TDP+LRP+++QLDR QRSRA
Sbjct  305  DIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRTQRSRA  364

Query  361  WNDSKVTAHHGIIPTLEPANLTAMSDKEQAVYKLIRAHYLAQFLPQHEFDRTTACLSCTG  420
            WNDSKV+AHHGIIPTLEPANL+A+SDK  AVY+LIRAHYLAQFLP+ EFDRTTA L C G
Sbjct  365  WNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQLLCGG  424

Query  421  ETLQAVGKQIVVIGWRQVLTEPRPDE-DGETTLRSQVLPALHEGLSCQITGIDCKALKTS  479
            +TLQAVGKQ+++ GW+QVL+ P +D+ DGE+  RSQVLPAL+EGLSCQ+  +D KALKT 
Sbjct  425  QTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLSCQVNHVDLKALKTQ  484

Query  480  PPRPYTQGELVKAMKGVAKLVSDPRLKQKLKDTTGIGTEATRANIIKGLLDRGYLLKKSR  539
            PP+PYTQG+L+KAMKGVAKLV+DPRLKQKLK+TTGIGTEATRA+IIKGLL+RGYLLKK+R
Sbjct  485  PPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERGYLLKKGR  544

Query  540  SVRASDAAFTLIDAVPGAIADPGMTAIWEQALDMIEAGQLTLDVFIDKQSAWITQLVQQY  599
            +VRASDAA  LIDAVP+AI+DPG TA+WEQALDMIEAG++TL+ F+ KQS+WITQLVQQY
Sbjct  545  TVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWITQLVQQY  604

Query  600  RGASLSIKVPQGPACPECGTAMRQRTGKSGPFWSCPRYPDCKGSQPIDSGKH---KRAMP  656
            R+A+L+IK+P+GPACP CG+A RQRTGK+GPFWSC RYPDCKG+ P+++G++   KR+ +
Sbjct  605  RAATLAIKLPEGPACPLCGSATRQRTGKTGPFWSCCRYPDCKGTLPVQNGRQASAKRSTS  664

Query  657  RKRSRSSR  664
            RK  + ++
Sbjct  665  RKPRQIPK  672

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  863 bits (3268),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 503/668 (76%), Positives = 613/668 (92%), Gaps = 4/668 (0%)

Query  1    MRLFLCEKPSQGKDIGRILGATQRGEGCLNGSGVTVTWCIGHLVEAAAPEAYDEQLKRWS  60
            MRLFLCEKPSQGKDI+R+LGA QRG GC NG+G  VTWCIGHL+EAA+PEAY+EQ KRWS
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQYKRWS  60

Query  61   IEQLPIIPQRWQVEVKPKTATQFKVVKALLAKATQLVIATDADREGELIAREIIDLCGYR  120
            +EQLPIIP+RW+VE K+ TA+Q+K+VK L+++A++LVIATDADREGE+IAREIIDLCGYR
Sbjct  61   LEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGYR  120

Query  121  GPIERLWLSALNDASIRAALGKLRPSAETLPMYYSALARSRADWLVGMNLSRLFTVLGRQ  180
            GPI+RLWLSALNDASIR ALG L+PS+E+LP+Y +ALARSRADWLVGMNLSRLFT+LGRQ
Sbjct  121  GPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGRQ  180

Query  181  AGYDGVLSVGRVQTPTLKLVVDRDREIAAFVSVPYWAIDVYLTTSGQAFTAQWVSPDTCT  240
            AGYDGVLSVGRVQTPTL LVV RDREIA FVSVP+W+I+V L+T+G++F A W+++D C+
Sbjct  181  AGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGCS  240

Query  241  DDSGRCLqqpvaqqaaqqIRATGSAQVVSVETERVREGPPLPFDLGTLQELCSKQLGLDV  300
            DD+GRCLQQ+ AQQAA+++R +GSAQVV+V TERVRE+PPLPFDLGTLQ++CS+QL+LDV
Sbjct  241  DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALDV  300

Query  301  QETLDIAQALYETHKATTYPRSDSGYLPESMFAEVPIVLDSLLKTDFSLRPIIDQLDRTQ  360
            QETLDIAQALYETHKATTYPRSDSGYLPESM+AEVP VL ++L TD SLRP+++QLDRTQ
Sbjct  301  QETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRTQ  360

Query  361  RSRAWNDAKVSAHHGIIPTLEPANLSAMSEKELAVYKLIRAHYLAQFLPHHEFDRTVANL  420
            RSRAWND+KVSAHHGIIPTLEPANL+A+S+K LAVY+LIRAHYLAQFLPH EFDRT A+L
Sbjct  361  RSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQL  420

Query  421  SCGQQTLTATGKQVVVKGWRLVLAEPQPEE-DSDTAARSQVLPALREGVSCQVADVDLKA  479
             CG QTL A GKQV++ GW+ VLA P++++ D+++ +RSQVLPALREG+SCQV +VDLKA
Sbjct  421  LCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLSCQVNHVDLKA  480

Query  480  LKTQPSRPYTQGELVKSMKGVAKLVSDPRLKQKLKDTVGIGTEATRANIISGLIARGYLM  539
            LKTQP++PYTQG+L+K+MKGVAKLV+DPRLKQKLK+T GIGTEATRA+II GL+ RGYL+
Sbjct  481  LKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERGYLL  540

Query  540  KKGRAIRASDAAFTLIDAVPAAIADPGTTAVWEQALDMIEAGQLTLDVFIGKQAAWISQL  599
            KKGR++RASDAA  LIDAVPAAI+DPGTTAVWEQALDMIEAG++TL+ F++KQ++WI+QL
Sbjct  541  KKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWITQL  600

Query  600  ITQYASASLSIKVPHGPACPQCGAPTRQRSGKSGPFWSCSRYPDCKGTLPVESG---TSK  656
            + QY +A+L+IK+P+GPACP CG++TRQR+GK+GPFWSC RYPDCKGTLPV++G   ++K
Sbjct  601  VQQYRAATLAIKLPEGPACPLCGSATRQRTGKTGPFWSCCRYPDCKGTLPVQNGRQASAK  660

Query  657  RVASRSRR  664
            R +SR  R
Sbjct  661  RSTSRKPR  668

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  862 bits (3265),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 503/668 (76%), Positives = 613/668 (92%), Gaps = 4/668 (0%)

Query  1    MRLFLCEKPSQGKDIGRILGATQRGEGCLNGSGVTVTWCIGHLVEAAAPEAYDEQLKRWS  60
            MRLFLCEKPSQGKDI+R+LGA QRG GC NG+G  VTWCIGHL+EAA+PEAY+EQ KRWS
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQYKRWS  60

Query  61   IEQLPIIPQRWQVEVKPKTATQFKVVKALLAKATQLVIATDADREGELIAREIIDLCGYR  120
            +EQLPIIP+RW+VE K+ TA+Q+K+VK L+++A++LVIATDADREGE+IAREIIDLCGYR
Sbjct  61   LEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGYR  120

Query  121  GPIERLWLSALNDASIRAALGKLRPSAETLPMYYSALARSRADWLVGMNLSRLFTVLGRQ  180
            GPI+RLWLSALNDASIR ALG L+PS+E+LP+Y +ALARSRADWLVGMNLSRLFT+LGRQ
Sbjct  121  GPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGRQ  180

Query  181  AGYDGVLSVGRVQTPTLKLVVDRDREIAAFVSVPYWAIDVYLTTSGQAFTAQWISPDTCT  240
            AGYDGVLSVGRVQTPTL LVV RDREIA FVSVP+W+I+V L+T+G++F A WI++D C+
Sbjct  181  AGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGCS  240

Query  241  DDSGRCLqqpvaqqaaqqIRATGSAQVVSVETERVREGPPLPFDLGTLQELCSKQLGLDV  300
            DD+GRCLQQ+ AQQAA+++R +GSAQVV+V TERVRE+PPLPFDLGTLQ++CS+QL+LDV
Sbjct  241  DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALDV  300

Query  301  QETLDIAQALYETHKATTYPRSDSGYLPESMFAEVPIVLDSLLKTDFSLRPIIDQLDRTQ  360
            QETLDIAQALYETHKATTYPRSDSGYLPESM+AEVP VL ++L TD SLRP+++QLDRTQ
Sbjct  301  QETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRTQ  360

Query  361  RSRAWNDAKVSAHHGIIPTLEPANLSAMSEKELAVYKLIRAHYLAQFLPHHEFDRTVANL  420
            RSRAWND+KVSAHHGIIPTLEPANL+A+S+K LAVY+LIRAHYLAQFLPH EFDRT A+L
Sbjct  361  RSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQL  420

Query  421  SCGQQTLTATGKQVVVKGWRLVLAEPQPEE-DSDTAARSQVLPALREGVSCQVADVDLKA  479
             CG QTL A GKQV++ GW+ VLA P++++ D+++ +RSQVLPALREG+SCQV +VDLKA
Sbjct  421  LCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLSCQVNHVDLKA  480

Query  480  LKTQPSRPYTQGELVKSMKGVAKLVSDPRLKQKLKDTVGIGTEATRANIISGLIARGYLM  539
            LKTQP++PYTQG+L+K+MKGVAKLV+DPRLKQKLK+T GIGTEATRA+II GL+ RGYL+
Sbjct  481  LKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERGYLL  540

Query  540  KKGRAIRASDAAFTLIDAVPAAIADPGTTAVWEQALDMIEAGQLTLDVFIGKQAAWISQL  599
            KKGR++RASDAA  LIDAVPAAI+DPGTTAVWEQALDMIEAG++TL+ F++KQ++WI+QL
Sbjct  541  KKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWITQL  600

Query  600  ITQYASASLSIKVPHGPACPQCGAPTHQRSGKSGPFWSCSRYPDCKGTLPVESG---TSK  656
            + QY +A+L+IK+P+GPACP CG++T+QR+GK+GPFWSC RYPDCKGTLPV++G   ++K
Sbjct  601  VQQYRAATLAIKLPEGPACPLCGSATRQRTGKTGPFWSCCRYPDCKGTLPVQNGRQASAK  660

Query  657  RVASRSRR  664
            R +SR  R
Sbjct  661  RSTSRKPR  668

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  861 bits (3261),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 502/668 (76%), Positives = 612/668 (92%), Gaps = 4/668 (0%)

Query  1    MRLFLCEKPSQGKDIGRILGATQRGEGCLNGSGVTVTWCIGHLVEAAAPEAYDEQLKRWS  60
            MRLFLCEKPSQGKDI+R+LGA QRG GC NG+G  VTWCIGHL+EAA+PEAY+EQ KRWS
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQYKRWS  60

Query  61   IEQLPIIPQRWQVEVKPKTATQFKVVKALLAKATQLVIATDADREGELIAREIIDLCGYR  120
            +EQLPIIP+RW+VE K+ TA+Q+K+VK L+++A++LVIATDADREGE+IAREIIDLCGYR
Sbjct  61   LEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGYR  120

Query  121  GPIERLWLSALNDASIRAALGKLRPSAETLPMYYSALARSRADWLVGMNLSRLFTVLGRQ  180
            GPI+RLWLSALNDASIR ALG L+PS+E+LP+Y +ALARSRADWLVGMNLSRLFT+LGRQ
Sbjct  121  GPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGRQ  180

Query  181  AGYDGVLSVGRVQTPTLKLVVDRDREIAAFVSVPYWAIDVYLTTSGQAFTAQWVSPDTCT  240
            AGYDGVLSVGRVQTPTL LVV RDREIA FVSVP+W+I+V L+T+G++F A W+++D C+
Sbjct  181  AGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGCS  240

Query  241  DDSGRCLqqpvaqqaaqqLRATGSAQVVSVETERVREGPPLPFDLGTLQELCSKQLGLDV  300
            DD+GRCLQQ+ AQQAA++LR +GSAQVV+V TERVRE+PPLPFDLGTLQ++CS+QL+LDV
Sbjct  241  DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALDV  300

Query  301  QETLDIAQALYETHKATTYPRSDSGYLPESMFAEVPIVLDSLLKTDFSLRPIIDQLDRTQ  360
            QETLDIAQALYETHKATTYPRSDSGYLPESM+AEVP VL ++L TD SLRP+++QLDRTQ
Sbjct  301  QETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRTQ  360

Query  361  RSRAWNDAKVSAHHGIIPTLEPANLSAMSEKELAVYKLIRAHYLAQFLPHHEFDRTVANL  420
            RSRAWND+KVSAHHGIIPTLEPANL+A+S+K LAVY+LIRAHYLAQFLPH EFDRT A+L
Sbjct  361  RSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQL  420

Query  421  SCGQQTLTATGKQVVVKGWRLVLAEPQPEE-DSDTAARSQVLPALREGVSCQVADADLKA  479
             CG QTL A GKQV++ GW+ VLA P++++ D+++ +RSQVLPALREG+SCQV + DLKA
Sbjct  421  LCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLSCQVNHVDLKA  480

Query  480  LKTQPSRPYTQGELVKSMKGVAKLISDPRLKQKLKDTVGIGTEATRANIISGLIARGYLM  539
            LKTQP++PYTQG+L+K+MKGVAKL++DPRLKQKLK+T GIGTEATRA+II GL+ RGYL+
Sbjct  481  LKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERGYLL  540

Query  540  KKGRAIRASDAAFTLIDAVPAAIADPGTTAVWEQALDMIEAGQLTLDVFIGKQAAWISQL  599
            KKGR++RASDAA  LIDAVPAAI+DPGTTAVWEQALDMIEAG++TL+ F++KQ++WI+QL
Sbjct  541  KKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWITQL  600

Query  600  ITQYASASLSIKVPHGPACPQCGAPTRQRSGKSGPFWSCSRYPDCKGTLPVESG---TSK  656
            + QY +A+L+IK+P+GPACP CG++TRQR+GK+GPFWSC RYPDCKGTLPV++G   ++K
Sbjct  601  VQQYRAATLAIKLPEGPACPLCGSATRQRTGKTGPFWSCCRYPDCKGTLPVQNGRQASAK  660

Query  657  RVASRSRR  664
            R +SR  R
Sbjct  661  RSTSRKPR  668

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  860 bits (3258),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 502/668 (76%), Positives = 612/668 (92%), Gaps = 4/668 (0%)

Query  1    MRLFLCEKPSQGKDIGRILGATQRGEGCLNGSGVTVTWCIGHLVEAAAPEAYDEQLKRWS  60
            MRLFLCEKPSQGKDI+R+LGA QRG GC NG+G  VTWCIGHL+EAA+PEAY+EQ KRWS
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQYKRWS  60

Query  61   IEQLPIIPQRWQVEVKPKTATQFKVVKALLAKATQLVIATDADREGELIAREIIDLCGYR  120
            +EQLPIIP+RW+VE K+ TA+Q+K+VK L+++A++LVIATDADREGE+IAREIIDLCGYR
Sbjct  61   LEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGYR  120

Query  121  GPIERLWLSALNDASIRAALGKLRPSAETLPMYYSALARSRADWLVGMNLSRLFTVLGRQ  180
            GPI+RLWLSALNDASIR ALG L+PS+E+LP+Y +ALARSRADWLVGMNLSRLFT+LGRQ
Sbjct  121  GPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGRQ  180

Query  181  AGYDGVLSVGRVQTPTLKLVVDRDREIAAFVSVPYWAIDVYLTTSGQAFTAQWVSPDTCT  240
            AGYDGVLSVGRVQTPTL LVV RDREIA FVSVP+W+I+V L+T+G++F A W+++D C+
Sbjct  181  AGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGCS  240

Query  241  DDSGRCLqqpvaqqaaqqIRATGSAQVVSVETERVREGPPLPFDLGTLQELCSKQLGLDV  300
            DD+GRCLQQ+ AQQAA+++R +GSAQVV+V TERVRE+PPLPFDLGTLQ++CS+QL+LDV
Sbjct  241  DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALDV  300

Query  301  QETLDIAQALYETHKATTYPRSDSGYLPESMFAEVPIVLDSLPKTDFSLRPIIDQLDRTQ  360
            QETLDIAQALYETHKATTYPRSDSGYLPESM+AEVP VL ++  TD SLRP+++QLDRTQ
Sbjct  301  QETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRTQ  360

Query  361  RSRAWNDAKVSAHHGIIPTLEPANLSAMSEKELAVYKLIRAHYLAQFLPHHEFDRTVANL  420
            RSRAWND+KVSAHHGIIPTLEPANL+A+S+K LAVY+LIRAHYLAQFLPH EFDRT A+L
Sbjct  361  RSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQL  420

Query  421  SCGQQTLTATGKQVVVKGWRLVLAEPQPEE-DSDTAARSQVLPALREGVSCQVADVDLKA  479
             CG QTL A GKQV++ GW+ VLA P++++ D+++ +RSQVLPALREG+SCQV +VDLKA
Sbjct  421  LCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLSCQVNHVDLKA  480

Query  480  LKTQPSRPYTQGELVKSMKGVAKLVSDPRLKQKLKDTVGIGTEATRANIISGLIARGYLM  539
            LKTQP++PYTQG+L+K+MKGVAKLV+DPRLKQKLK+T GIGTEATRA+II GL+ RGYL+
Sbjct  481  LKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERGYLL  540

Query  540  KKGRAIRASDAAFTLIDAVPAAIADPGTTAVWEQALDMIEAGQLTLDVFIGKQAAWISQL  599
            KKGR++RASDAA  LIDAVPAAI+DPGTTAVWEQALDMIEAG++TL+ F++KQ++WI+QL
Sbjct  541  KKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWITQL  600

Query  600  ITQYASASLSIKVPHGPACPQCGAPTRQRSGKSGPFWSCSRYPDCKGTLPVESG---TSK  656
            + QY +A+L+IK+P+GPACP CG++TRQR+GK+GPFWSC RYPDCKGTLPV++G   ++K
Sbjct  601  VQQYRAATLAIKLPEGPACPLCGSATRQRTGKTGPFWSCCRYPDCKGTLPVQNGRQASAK  660

Query  657  RVASRSRR  664
            R +SR  R
Sbjct  661  RSTSRKPR  668

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  856 bits (3240),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 491/666 (74%), Positives = 607/666 (92%), Gaps = 4/666 (0%)

Query  1    MRLFLCEKPSQGKDIGRVLGTTQRGNGCLTGSGITVTWCIGHLVEAAPPETYGEQYKRWS  60
            MRLFLCEKPSQGKDI+RVLG+ QRG+GC  G+G  VTWCIGHL+EAAPPE+YGEQYKRWS
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQYKRWS  60

Query  61   IEQLPIIPECWRVEVKSKTASQFNVVKELLSKATELVIATDADREGELIAREIIELCGYR  120
            +EQLPIIPE WRVE K+ TA+Q+++VK+L+++A+ELVIATDADREGE+IAREII+LCGYR
Sbjct  61   LEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGYR  120

Query  121  GPIQRLWLSALNDTSIRKALSVLRPSDETLPMYFSALARSRADWLIGMNLSRLFTVLGRQ  180
            GPIQRLWLSALND+SIRKAL+ L+PS E+LP+Y +ALARSRADWL+GMNLSRLFT+LGRQ
Sbjct  121  GPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGRQ  180

Query  181  AGYDGVLSVGRVQTPTLKLVVDRDREIARFVSVPFWAVEVVLSSAGQHFTAAWLAPDTAA  240
            AGYDGVLSVGRVQTPTL LVV RDREIARFVSVPFW++EV LS++G+ F A+W+A+D  +
Sbjct  181  AGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGCS  240

Query  241  DNAGRCLQEPIARQATERMRVTGSAQVTSVETEHMREGPPLPFDLGTLQEVCSRQLGLDV  300
            D+AGRCLQ++ A+QA++R+RV+GSAQV +V TE++RE+PPLPFDLGTLQ+VCSRQL+LDV
Sbjct  241  DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALDV  300

Query  301  QETLEIAQALYETHKATTYPRSDSGYLPESMFAEVPIVFDSLLKTDPDLRPIVDLLDRNQ  360
            QETL+IAQALYETHKATTYPRSDSGYLPESM+AEVP V+ ++L TDP LRP+++ LDR Q
Sbjct  301  QETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRTQ  360

Query  361  RSRAWNDSKVTAHHGIIPTLEPANLAAMSDKERAVYTLIRTHYLAQFLPHHEFDHTTAYL  420
            RSRAWNDSKV+AHHGIIPTLEPANLAA+SDK  AVY LIR+HYLAQFLPH EFD+TTA L
Sbjct  361  RSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQL  420

Query  421  SCAGEMLQAVGKQVVLVGWRRVLTEPKPDD-DGDTTSRSQVLPPLNEGLSCQITGIDCKA  479
             C+G+ LQAVGKQV++ GW++VL+ P +D+ DG++ +RSQVLP+L EGLSCQ+  +D KA
Sbjct  421  LCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLSCQVNHVDLKA  480

Query  480  LKTSPPRPYTQGELVKSMKSVAKLVSDPRLKQTLKDTTGIGTEATRANIIKGLLDRGYLL  539
            LKT PP+PYTQG+L+K+MK+VAKLV+DPRLKQ LK+TTGIGTEATRA+IIKGLL+RGYLL
Sbjct  481  LKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERGYLL  540

Query  540  KKGRSVRASDAAFTLIDAVPGAIADPGMTAIWEQALDMIESGQLTLDVFIDKQSAWIAQL  599
            KKGR+VRASDAA  LIDAVP+AI+DPG TA+WEQALDMIE+G++TL+ F+ KQS+WI+QL
Sbjct  541  KKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWITQL  600

Query  600  IQQYRGASLSIQMPLGPACPECGTPMHQRPGKNGAFWSCPRYPDCRGSLPIDSGKR---K  656
            +QQYR+A+L+I++P GPACP CG++ +QR GK G+FWSC RYPDC+G+LP+++G++   K
Sbjct  601  VQQYRAATLAIKLPEGPACPLCGSATRQRTGKTGPFWSCCRYPDCKGTLPVQNGRQASAK  660

Query  657  RTTPRK  662
            R+T+RK
Sbjct  661  RSTSRK  666

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  851 bits (3221),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 502/669 (76%), Positives = 604/669 (91%), Gaps = 4/669 (0%)

Query  1    MRLFLCEKPSQGKDIGRILGATQRGEGCLSGSGVIVTWCIGHLVEAAAPEVYDAALKRWS  60
            MRLFLCEKPSQGKDI+R+LGA QRG GC +G+G +VTWCIGHL+EAA+PE Y+   KRWS
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQYKRWS  60

Query  61   LEQLPIIPQQWRVEVKPKTATQFKVVKALLAKATHLVIATDADREGELIAREIIDLCGYR  120
            LEQLPIIP++WRVE K+ TA+Q+K+VK L+++A++LVIATDADREGE+IAREIIDLCGYR
Sbjct  61   LEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGYR  120

Query  121  GPIERLWLSALNDASIRTALGKLRPSSDTLPMYYSAQARSRADWLVGMNLSRLFTVLGRQ  180
            GPI+RLWLSALNDASIR ALG L+PSS++LP+Y +A ARSRADWLVGMNLSRLFT+LGRQ
Sbjct  121  GPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGRQ  180

Query  181  AGYDGVLSVGRVQTPTLKLVVDRDREIAAFKSVPFWAIDVSLSAGGQAFSAQWVPPDGCI  240
            AGYDGVLSVGRVQTPTL LVV RDREIA F SVPFW+I+V+LS+GG++F A W+++DGC 
Sbjct  181  AGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGCS  240

Query  241  DDAGRCLqqpvaqqaaqqiraagsaqVVSVETKRVREGPPLLFDLGTLQEVCSKQLGLDV  300
            DDAGRCLQQ+ AQQAA+++R AGSAQVV+V T RVRE+PPL FDLGTLQ+VCS+QL+LDV
Sbjct  241  DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALDV  300

Query  301  QETLEIAQALYETHKATTYPRSDSGYLPESMFAEVPTVLDSLLKTDPSLRPIMGQLDRSQ  360
            QETL+IAQALYETHKATTYPRSDSGYLPESM+AEVP+VL ++L TDPSLRP++ QLDR+Q
Sbjct  301  QETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRTQ  360

Query  361  RSRAWNDGKVTAHHGIIPTLEPANLSVMSEKELAVYRLIRAHYLAQFLPHHEFDRTVAEL  420
            RSRAWND+KV+AHHGIIPTLEPANL+ +S+K LAVYRLIRAHYLAQFLPH EFDRT A+L
Sbjct  361  RSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQL  420

Query  421  SCGQQKLAATGKQVVAQGWRLVLAEPQADE-DGDDAARSQVLPALREGMACQVAEAEIKA  479
             CG Q L A GKQV+  GW+ VLA P+AD+ DG+  +RSQVLPALREG++CQV + ++KA
Sbjct  421  LCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLSCQVNHVDLKA  480

Query  480  LKTMPPKPYTQGELVKSMKGVAKLVTDPRLKQKLKETVGIGTEATRANIISGLIARGYLV  539
            LKT PPKPYTQG+L+K+MKGVAKLVTDPRLKQKLKET GIGTEATRA+II GL+ RGYL+
Sbjct  481  LKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERGYLL  540

Query  540  KKGRSIRASDAAFTLIDAVPTAIADPGTTAVWEQALDMIEAGQLTLDVFIGKQAAWISQL  599
            KKGR++RASDAA  LIDAVP+AI+DPGTTAVWEQALDMIEAG++TL+ F++KQ++WI+QL
Sbjct  541  KKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWITQL  600

Query  600  IAQYGSTSLSIKVPQGPACPQCGATTRQRTGKTGPFWSCSRYPDCKGTLPVDSGTSKRGA  659
            + QY +++L+IK+P+GPACP CG++TRQRTGKTGPFWSC RYPDCKGTLPV++G   R A
Sbjct  601  VQQYRAATLAIKLPEGPACPLCGSATRQRTGKTGPFWSCCRYPDCKGTLPVQNG---RQA  657

Query  660  SRPRTSGRK  668
            S  R+++RK
Sbjct  658  SAKRSTSRK  666

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  849 bits (3216),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 491/654 (76%), Positives = 599/654 (92%), Gaps = 2/654 (0%)

Query  1    MRLFLCEKPSQGKDIGRILGATQRGEGCLNGSGVTVTWCIGHLVEAATPEAYDEQLKRWS  60
            MRLFLCEKPSQGKDI+R+LGA QRG GC NG+G  VTWCIGHL+EAA PEAY+EQ KRWS
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQYKRWS  60

Query  61   IEQLPIIPQHWRVEVKPKTATQFKVVKALLAKATQLVIATDADREGELIAREIIELCGYR  120
            +EQLPIIP++WRVE K+ TA+Q+K+VK L+++A++LVIATDADREGE+IAREII+LCGYR
Sbjct  61   LEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGYR  120

Query  121  GPIERLWLSALNDASIRAALGKLRPSAETLPMYHSALARSRADWLVGMNLSRLFTVLGRQ  180
            GPI+RLWLSALNDASIR ALG L+PS+E+LP+Y +ALARSRADWLVGMNLSRLFT+LGRQ
Sbjct  121  GPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGRQ  180

Query  181  AGYDGVLSVGRVQTPTLKLVVDRDREIAAFVSVPYWAIVVSLSAGVQAFTAHWVPPNACT  240
            AGYDGVLSVGRVQTPTL LVV RDREIA FVSVP+W+I V+LS+G ++F A W+++++C+
Sbjct  181  AGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGCS  240

Query  241  DDAGRCLqqpvaqqamqqIRAAGSAHVVSVETERVREGPPLPFDLGTLQEVCSKQLGLDV  300
            DDAGRCLQQ+ AQQA +++R AGSA+VV+V TERVRE+PPLPFDLGTLQ+VCS+QL+LDV
Sbjct  241  DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALDV  300

Query  301  QETLEIAQALYETHKATTYPRSDSGYLPESMFAEVTTVLDSLLKTDPSLRSIIGQLDRLQ  360
            QETL+IAQALYETHKATTYPRSDSGYLPESM+AEV +VL ++L TDPSLR+++ QLDR Q
Sbjct  301  QETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRTQ  360

Query  361  RSRAWNDGKVTAHHGIIPTLEPANLSAMSEKELAVYRLIRAHYLAQFLPHHEFDHTVAKL  420
            RSRAWND+KV+AHHGIIPTLEPANL+A+S+K LAVYRLIRAHYLAQFLPH EFD+T A+L
Sbjct  361  RSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQL  420

Query  421  SCGGQNLAATGKQVVTPGWRQVLAEPQSEdgdgdgdTAARAQVLPALHEGLACQVADIDL  480
             CGGQ L A GKQV+ PGW+QVLA P+++  ++DG++ +R+QVLPAL+EGL+CQV ++DL
Sbjct  421  LCGGQTLQAVGKQVIIPGWHQVLAGPEAD--NADGEAVPRSQVLPALREGLSCQVNHVDL  478

Query  481  KALKTLPPKPYTQGELVKSMKGVAKLVSDPRLKQKLKDTVGIGTEATRANIIGGLIARGY  540
            KALKT PPKPYTQG+L+K+MKGVAKLV+DPRLKQKLK+T GIGTEATRA+II GL+ RGY
Sbjct  479  KALKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERGY  538

Query  541  LVKKGRAIRASDAAFTLIDAVPAAIADPGTTAVWEQALDMIEAGQLTLDVFIGKQAAWIS  600
            L+KKGR++RASDAA  LIDAVPAAI+DPGTTAVWEQALDMIEAG++TL+ F++KQ++WI+
Sbjct  539  LLKKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWIT  598

Query  601  QLIAQYGNASLSIKAPQGPTCPQCGAPTRQRSSKSGPFWSCSRYPDCKGTLPVE  654
            QL+ QY  A+L+IK P+GP+CP CG++TRQR++K+GPFWSC RYPDCKGTLPV+
Sbjct  599  QLVQQYRAATLAIKLPEGPACPLCGSATRQRTGKTGPFWSCCRYPDCKGTLPVQ  652

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  848 bits (3210),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 506/669 (76%), Positives = 608/669 (91%), Gaps = 4/669 (0%)

Query  1    MRLFLCEKPSQGKDIGRILGATQRGEGCLSGSGVTVTWCIGHLVEAAAPEVYDAALKRWS  60
            MRLFLCEKPSQGKDI+R+LGA QRG GC +G+G  VTWCIGHL+EAA+PE Y+   KRWS
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQYKRWS  60

Query  61   LEQLPIVPQQWRVEVKPKTATQFKVVKALLAKATHLVIATDADREGELIAREIIDLCGYR  120
            LEQLPI+P++WRVE K+ TA+Q+K+VK L+++A++LVIATDADREGE+IAREIIDLCGYR
Sbjct  61   LEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGYR  120

Query  121  GPIERLWLSALNDASIRTALGKLRPSSDTLPMYYSALARSRADWLVGMNLSRLFTVLGRQ  180
            GPI+RLWLSALNDASIR ALG L+PSS++LP+Y +ALARSRADWLVGMNLSRLFT+LGRQ
Sbjct  121  GPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGRQ  180

Query  181  AGYDGVLSVGRVQTPTLKLVVDRDREIAAFKSVPFWAIDVSLSAGGQAFSAQWVPPDGCT  240
            AGYDGVLSVGRVQTPTL LVV RDREIA F SVPFW+I+V+LS+GG++F A W+++DGC+
Sbjct  181  AGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGCS  240

Query  241  DDAGRCLqqpiaqqaaqqiraassaqVVSVETERVREGPPLLFDLGTLQEVCSKQLGLDV  300
            DDAGRCLQQ+ AQQAA+++R A+SAQVV+V TERVRE+PPL FDLGTLQ+VCS+QL+LDV
Sbjct  241  DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALDV  300

Query  301  QETLEIAQALYETHKATTYPRSDSGYLPESMFAEVPTVLDSLLKTDPSLRPIMGQLDRSQ  360
            QETL+IAQALYETHKATTYPRSDSGYLPESM+AEVP+VL ++L TDPSLRP++ QLDR+Q
Sbjct  301  QETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRTQ  360

Query  361  RSRAWNDGKVTAHHGIIPTLEPANLSAMSEKELAVYWLIRAHYLAQFLPHHEFDRTIAEL  420
            RSRAWND+KV+AHHGIIPTLEPANL+A+S+K LAVY+LIRAHYLAQFLPH EFDRT A+L
Sbjct  361  RSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQL  420

Query  421  SCGQQKLVATGKQVAAQGWHLVLAEPQADE-DGETTARSQVLPALREGLACQVAEAEVKA  479
             CG Q L A GKQV   GWH VLA P+AD+ DGE+ +RSQVLPALREGL+CQV + ++KA
Sbjct  421  LCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLSCQVNHVDLKA  480

Query  480  LKTLPPKPYTQGELVKSMKGVARFVTDPRLKQKLKDTTGIGTEATRANIITGLLTRGYLV  539
            LKT PPKPYTQG+L+K+MKGVA++VTDPRLKQKLK+TTGIGTEATRA+II GLL RGYL+
Sbjct  481  LKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERGYLL  540

Query  540  KKGRSIRASDAAFTLIDAVPAAIADPGTTAVWEQALDMIEAGQLTLDVFIGKQAAWISQL  599
            KKGR++RASDAA  LIDAVPAAI+DPGTTAVWEQALDMIEAG++TL+ F++KQ++WI+QL
Sbjct  541  KKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWITQL  600

Query  600  IVQYGSTSLSIKVPQGPACPQCGAPTRQRTGKTGPFWSCSRYPDCKGTLPVDSGTSKRGA  659
            + QY +++L+IK+P+GPACP CG++TRQRTGKTGPFWSC RYPDCKGTLPV++G   R A
Sbjct  601  VQQYRAATLAIKLPEGPACPLCGSATRQRTGKTGPFWSCCRYPDCKGTLPVQNG---RQA  657

Query  660  SRPRSSGRK  668
            S  RS++RK
Sbjct  658  SAKRSTSRK  666

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  847 bits (3209),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 498/668 (75%), Positives = 610/668 (92%), Gaps = 4/668 (0%)

Query  1    MRLFLCEKPSQGKDIGRILGATQRGEGCLNGSGVTVTWCIGHLVEAAAPEAYDEQLKRWS  60
            MRLFLCEKPSQGKDI+R+LGA QRG GC NG+G  VTWCIGHL+EAA+PEAY+EQ KRWS
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQYKRWS  60

Query  61   IEQLPIIPQNWRVEVKPKTATQFKVVKALLAKATQLVIATDADREGELIAREIIELCGYR  120
            +EQLPIIP+ WRVE K+ TA+Q+K+VK L+++A++LVIATDADREGE+IAREII+LCGYR
Sbjct  61   LEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGYR  120

Query  121  GPIERLWLSALNDASIRAALGKLRPSAETLPMYYSALARSRADWLVGMNLSRLFTVLGRQ  180
            GPI+RLWLSALNDASIR ALG L+PS+E+LP+Y +ALARSRADWLVGMNLSRLFT+LGRQ
Sbjct  121  GPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGRQ  180

Query  181  AGYDGVLSVGRVQTPTLKLVVDRDREIAAFVSVPYWAIDVSLSASGQSFTAQWVPPDAYT  240
            AGYDGVLSVGRVQTPTL LVV RDREIA FVSVP+W+I+V+LS++G+SF A W+++D+ +
Sbjct  181  AGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGCS  240

Query  241  DDTGRCLQQPVaqraaqqirgagsaqVVSVETERVREGPPLLFDLGTLQEVCSKQLGLDV  300
            DD+GRCLQQ+ AQ+AA+++R AGSAQVV+V TERVRE+PPL FDLGTLQ+VCS+QL+LDV
Sbjct  241  DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALDV  300

Query  301  QETLEIAQALYETHKATTYPRSDSGYLPESMFAEVSTVLDSLLRTDPSLRPIMDQLDRSQ  360
            QETL+IAQALYETHKATTYPRSDSGYLPESM+AEV++VL ++L TDPSLRP+++QLDR+Q
Sbjct  301  QETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRTQ  360

Query  361  RSRAWNDGKVTAHHGIIPTLEPANLSAMSEKELAVYRLIRAHYLAQFLPHHEFDRTVANL  420
            RSRAWND+KV+AHHGIIPTLEPANL+A+S+K LAVYRLIRAHYLAQFLPH EFDRT A+L
Sbjct  361  RSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQL  420

Query  421  ACGQQKLAATGKQVVVKGWPLVLTEPQPDE-DGDAAARSQVLPALREGLACLVADVDLKA  479
             CG Q L A GKQV++ GW  VL+ P++D+ DG+A +RSQVLPALREGL+C V +VDLKA
Sbjct  421  LCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLSCQVNHVDLKA  480

Query  480  LKTLPPRPYTQGELVKSMKGVAKLVTDPRLKQKFRDTVGIGTEATRANIISGLIARGYIV  539
            LKT PP+PYTQG+L+K+MKGVAKLVTDPRLKQK+++T GIGTEATRA+II GL+ RGY++
Sbjct  481  LKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERGYLL  540

Query  540  KKGRAIRASDAAFTLIDAVPAAIADPGTTAVWEQALDMIEAGQLTLDVFIGKQAAWISQL  599
            KKGR++RASDAA  LIDAVPAAI+DPGTTAVWEQALDMIEAG++TL+ F++KQ++WI+QL
Sbjct  541  KKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWITQL  600

Query  600  IAQYSIASLSIKVPQGPACPQCGAPTRQRSGKSGPFWSCSRYPDCKGTLPVESG---TSK  656
            + QY  A+L+IK+P+GPACP CG++TRQR+GK+GPFWSC RYPDCKGTLPV++G   ++K
Sbjct  601  VQQYRAATLAIKLPEGPACPLCGSATRQRTGKTGPFWSCCRYPDCKGTLPVQNGRQASAK  660

Query  657  RGASRPHR  664
            R++SR  R
Sbjct  661  RSTSRKPR  668

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  847 bits (3209),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 498/668 (75%), Positives = 610/668 (92%), Gaps = 4/668 (0%)

Query  1    MRLFLCEKPSQGKDIGRILGATQRGEGCLNGSGVTVTWCIGHLVEAAAPEAYDEQLKRWS  60
            MRLFLCEKPSQGKDI+R+LGA QRG GC NG+G  VTWCIGHL+EAA+PEAY+EQ KRWS
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQYKRWS  60

Query  61   IEQLPIIPQNWRVEVKPKTATQFKVVKALLAKATQLVIATDADREGELIAREIIELCGYR  120
            +EQLPIIP+ WRVE K+ TA+Q+K+VK L+++A++LVIATDADREGE+IAREII+LCGYR
Sbjct  61   LEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGYR  120

Query  121  GPIERLWLSALNDASIRAALGKLRPSAETLPMYYSALARSRADWLVGMNLSRLFTVLGRQ  180
            GPI+RLWLSALNDASIR ALG L+PS+E+LP+Y +ALARSRADWLVGMNLSRLFT+LGRQ
Sbjct  121  GPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGRQ  180

Query  181  AGYDGVLSVGRVQTPTLKLVVDRDREIAAFVSVPYWAIDVSLSASGQSFTAQWVPPDAYT  240
            AGYDGVLSVGRVQTPTL LVV RDREIA FVSVP+W+I+V+LS++G+SF A W+++D+ +
Sbjct  181  AGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGCS  240

Query  241  DDTGRCLQQPVaqraaqqirgagsaqVVSVETERVREGPPLLFDLGTLQEVCSKQLGLDV  300
            DD+GRCLQQ+ AQ+AA+++R AGSAQVV+V TERVRE+PPL FDLGTLQ+VCS+QL+LDV
Sbjct  241  DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALDV  300

Query  301  QETLEIAQALYETHKATTYPRSDSGYLPESMFAEVSTVLDSLLRTDPSLRPIMDQLDRSQ  360
            QETL+IAQALYETHKATTYPRSDSGYLPESM+AEV++VL ++L TDPSLRP+++QLDR+Q
Sbjct  301  QETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRTQ  360

Query  361  RSRAWNDGKVTAHHGIIPTLEPANLSAMSEKELAVYRLIRAHYLAQFLPHHEFDRTVANL  420
            RSRAWND+KV+AHHGIIPTLEPANL+A+S+K LAVYRLIRAHYLAQFLPH EFDRT A+L
Sbjct  361  RSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQL  420

Query  421  ACGQQKLAATGKQVVVKGWPLVLTEPQPDE-DGDAAARSQVLPALREGLACLVADVDLKA  479
             CG Q L A GKQV++ GW  VL+ P++D+ DG+A +RSQVLPALREGL+C V +VDLKA
Sbjct  421  LCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLSCQVNHVDLKA  480

Query  480  LKTLPPRPYTQGELVKSMKGVAKLVTDPRLKQKFRDTVGIGTEATRANIISGLIARGYIV  539
            LKT PP+PYTQG+L+K+MKGVAKLVTDPRLKQK+++T GIGTEATRA+II GL+ RGY++
Sbjct  481  LKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERGYLL  540

Query  540  KKGRAIRASDAAFTLIDAVPAAIADPGTTAVWEQALDMIEAGQLTLDVFIGKQAAWISQL  599
            KKGR++RASDAA  LIDAVPAAI+DPGTTAVWEQALDMIEAG++TL+ F++KQ++WI+QL
Sbjct  541  KKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWITQL  600

Query  600  IAQYSIASLSIKVPQGPACPQCGAPTRQRSGKSGPFWSCSRYPDCKGTLPVESG---TSK  656
            + QY  A+L+IK+P+GPACP CG++TRQR+GK+GPFWSC RYPDCKGTLPV++G   ++K
Sbjct  601  VQQYRAATLAIKLPEGPACPLCGSATRQRTGKTGPFWSCCRYPDCKGTLPVQNGRQASAK  660

Query  657  RGASRPHR  664
            R++SR  R
Sbjct  661  RSTSRKPR  668

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  846 bits (3203),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 492/654 (76%), Positives = 596/654 (92%), Gaps = 1/654 (0%)

Query  1    MRLFLCEKPSQGKDIGRILGATQRGEGCLSGSGVTITWCIGHLVEAAAPEVYDAALKRWS  60
            MRLFLCEKPSQGKDI+R+LGA QRG GC +G+G  +TWCIGHL+EAA+PE Y+   KRWS
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQYKRWS  60

Query  61   LEQLPIIPQQWRVEVKPKTATQFKVVKALLAKATHLVIATDADREGELIAREIIDLCGYR  120
            LEQLPIIP++WRVE K+ TA+Q+K+VK L+++A++LVIATDADREGE+IAREIIDLCGYR
Sbjct  61   LEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGYR  120

Query  121  GPIERLWLSALNDASIRTALGKLRPSSDTLPMYYSALARSRADWLVGMNLSRLFTLLGRQ  180
            GPI+RLWLSALNDASIR ALG L+PSS++LP+Y +ALARSRADWLVGMNLSRLFTLLGRQ
Sbjct  121  GPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGRQ  180

Query  181  AGYDGVLSVGRVQTPTLKLVVDRDREIAAFKSAPFWAIDVSLSTEGQAFSAQWVAPDGCT  240
            AGYDGVLSVGRVQTPTL LVV RDREIA F S PFW+I+V+LST G++F A W+A+DGC+
Sbjct  181  AGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGCS  240

Query  241  DDAGRClqqpvaqqaalqIRVADNTQVVSVETERVREGPPLLFDLSTLQEVCSKQLGLDV  300
            DDAGRCLQQ+ AQQAA ++RVA+++QVV+V TERVRE+PPL FDL+TLQ+VCS+QL+LDV
Sbjct  241  DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALDV  300

Query  301  QETLQIAQALYETHKATTYPRSDSGYLPESMFAEVPAVLDSLLKTDPSLRPIMSQLDRSQ  360
            QETL+IAQALYETHKATTYPRSDSGYLPESM+AEVPAVL ++L TDPSLRP++ QLDR+Q
Sbjct  301  QETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRTQ  360

Query  361  RSRAWNDGKVTAHHGIIPTLEPANLSPLSEKELAVYRLIRAHYLAQFLPHHEFDRTVAEF  420
            RSRAWND+KV+AHHGIIPTLEPANL+++S+K LAVYRLIRAHYLAQFLPH EFDRT A++
Sbjct  361  RSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQL  420

Query  421  SCGQQMLVATGKQVVVKGWRLVLAEPQADE-DGDDAARSQVLPPLRGGLACQVAEVEIKA  479
             CG Q L A GKQV++ GW+ VLA P+AD+ DG+  +RSQVLP+LR GL+CQV +V++KA
Sbjct  421  LCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLSCQVNHVDLKA  480

Query  480  LKTMPPKPYTQGELVKSMKGIARFVTDPRLKQKLKDTTGIGTEATRANIISVLIARGYIV  539
            LKT PPKPYTQG+L+K+MKG+A++VTDPRLKQKLK+TTGIGTEATRA+II  L+ RGY++
Sbjct  481  LKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERGYLL  540

Query  540  KKGRSIRASDAAFTLIDAVPAAIADPGTTAVWEQALDMIEAGQLTLDVFLSKQAAWISQL  599
            KKGR++RASDAA  LIDAVPAAI+DPGTTAVWEQALDMIEAG++TL+ F++KQ++WI+QL
Sbjct  541  KKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWITQL  600

Query  600  IAQYGSMSLSIKLPHGPACPQCGAATRQRTGKSGPFWSCSRYPDCKGTLPVESG  653
            + QY + +L+IKLP+GPACP CG+ATRQRTGK+GPFWSC RYPDCKGTLPV++G
Sbjct  601  VQQYRAATLAIKLPEGPACPLCGSATRQRTGKTGPFWSCCRYPDCKGTLPVQNG  654

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  846 bits (3203),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 492/654 (76%), Positives = 596/654 (92%), Gaps = 1/654 (0%)

Query  1    MRLFLCEKPSQGKDIGRILGATQRGEGCLSGSGVTITWCIGHLVEAAAPEVYDAALKRWS  60
            MRLFLCEKPSQGKDI+R+LGA QRG GC +G+G  +TWCIGHL+EAA+PE Y+   KRWS
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQYKRWS  60

Query  61   LEQLPIIPQQWRVEVKPKTATQFKVVKALLAKATHLVIATDADREGELIAREIIDLCGYR  120
            LEQLPIIP++WRVE K+ TA+Q+K+VK L+++A++LVIATDADREGE+IAREIIDLCGYR
Sbjct  61   LEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGYR  120

Query  121  GPIERLWLSALNDASIRTALGKLRPSSDTLPMYYSALARSRADWLVGMNLSRLFTLLGRQ  180
            GPI+RLWLSALNDASIR ALG L+PSS++LP+Y +ALARSRADWLVGMNLSRLFTLLGRQ
Sbjct  121  GPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGRQ  180

Query  181  AGYDGVLSVGRVQTPTLKLVVDRDREIAAFKSAPFWAIDVSLSTEGQAFSAQWVAPDGCT  240
            AGYDGVLSVGRVQTPTL LVV RDREIA F S PFW+I+V+LST G++F A W+A+DGC+
Sbjct  181  AGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGCS  240

Query  241  DDAGRClqqpvaqqaalqIRVADNTQVVSVETERVREGPPLLFDLSTLQEVCSKQLGLDV  300
            DDAGRCLQQ+ AQQAA ++RVA+++QVV+V TERVRE+PPL FDL+TLQ+VCS+QL+LDV
Sbjct  241  DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALDV  300

Query  301  QETLQIAQALYETHKATTYPRSDSGYLPESMFAEVPAVLDSLLKTDPSLRPIMSQLDRSQ  360
            QETL+IAQALYETHKATTYPRSDSGYLPESM+AEVPAVL ++L TDPSLRP++ QLDR+Q
Sbjct  301  QETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRTQ  360

Query  361  RSRAWNDGKVTAHHGIIPTLEPANLSPLSEKELAVYRLIRAHYLAQFLPHHEFDRTVAEF  420
            RSRAWND+KV+AHHGIIPTLEPANL+++S+K LAVYRLIRAHYLAQFLPH EFDRT A++
Sbjct  361  RSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQL  420

Query  421  SCGQQMLVATGKQVVVKGWRLVLAEPQADE-DGDDAARSQVLPPLRGGLACQVAEVEIKA  479
             CG Q L A GKQV++ GW+ VLA P+AD+ DG+  +RSQVLP+LR GL+CQV +V++KA
Sbjct  421  LCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLSCQVNHVDLKA  480

Query  480  LKTMPPKPYTQGELVKSMKGIARFVTDPRLKQKLKDTTGIGTEATRANIISVLIARGYIV  539
            LKT PPKPYTQG+L+K+MKG+A++VTDPRLKQKLK+TTGIGTEATRA+II  L+ RGY++
Sbjct  481  LKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERGYLL  540

Query  540  KKGRSIRASDAAFTLIDAVPAAIADPGTTAVWEQALDMIEAGQLTLDVFLSKQAAWISQL  599
            KKGR++RASDAA  LIDAVPAAI+DPGTTAVWEQALDMIEAG++TL+ F++KQ++WI+QL
Sbjct  541  KKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWITQL  600

Query  600  IAQYGSMSLSIKLPHGPACPQCGAATRQRTGKSGPFWSCSRYPDCKGTLPVESG  653
            + QY + +L+IKLP+GPACP CG+ATRQRTGK+GPFWSC RYPDCKGTLPV++G
Sbjct  601  VQQYRAATLAIKLPEGPACPLCGSATRQRTGKTGPFWSCCRYPDCKGTLPVQNG  654

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  846 bits (3203),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 492/654 (76%), Positives = 596/654 (92%), Gaps = 1/654 (0%)

Query  1    MRLFLCEKPSQGKDIGRILGATQRGEGCLSGSGVTITWCIGHLVEAAAPEVYDAALKRWS  60
            MRLFLCEKPSQGKDI+R+LGA QRG GC +G+G  +TWCIGHL+EAA+PE Y+   KRWS
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQYKRWS  60

Query  61   LEQLPIIPQQWRVEVKPKTATQFKVVKALLAKATHLVIATDADREGELIAREIIDLCGYR  120
            LEQLPIIP++WRVE K+ TA+Q+K+VK L+++A++LVIATDADREGE+IAREIIDLCGYR
Sbjct  61   LEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGYR  120

Query  121  GPIERLWLSALNDASIRTALGKLRPSSDTLPMYYSALARSRADWLVGMNLSRLFTLLGRQ  180
            GPI+RLWLSALNDASIR ALG L+PSS++LP+Y +ALARSRADWLVGMNLSRLFTLLGRQ
Sbjct  121  GPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGRQ  180

Query  181  AGYDGVLSVGRVQTPTLKLVVDRDREIAAFKSAPFWAIDVSLSTEGQAFSAQWVAPDGCT  240
            AGYDGVLSVGRVQTPTL LVV RDREIA F S PFW+I+V+LST G++F A W+A+DGC+
Sbjct  181  AGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGCS  240

Query  241  DDAGRClqqpvaqqaalqIRVADNTQVVSVETERVREGPPLLFDLSTLQEVCSKQLGLDV  300
            DDAGRCLQQ+ AQQAA ++RVA+++QVV+V TERVRE+PPL FDL+TLQ+VCS+QL+LDV
Sbjct  241  DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALDV  300

Query  301  QETLQIAQALYETHKATTYPRSDSGYLPESMFAEVPAVLDSLLKTDPSLRPIMSQLDRSQ  360
            QETL+IAQALYETHKATTYPRSDSGYLPESM+AEVPAVL ++L TDPSLRP++ QLDR+Q
Sbjct  301  QETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRTQ  360

Query  361  RSRAWNDGKVTAHHGIIPTLEPANLSPLSEKELAVYRLIRAHYLAQFLPHHEFDRTVAEF  420
            RSRAWND+KV+AHHGIIPTLEPANL+++S+K LAVYRLIRAHYLAQFLPH EFDRT A++
Sbjct  361  RSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQL  420

Query  421  SCGQQMLVATGKQVVVKGWRLVLAEPQADE-DGDDAARSQVLPPLRGGLACQVAEVEIKA  479
             CG Q L A GKQV++ GW+ VLA P+AD+ DG+  +RSQVLP+LR GL+CQV +V++KA
Sbjct  421  LCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLSCQVNHVDLKA  480

Query  480  LKTMPPKPYTQGELVKSMKGIARFVTDPRLKQKLKDTTGIGTEATRANIISVLIARGYIV  539
            LKT PPKPYTQG+L+K+MKG+A++VTDPRLKQKLK+TTGIGTEATRA+II  L+ RGY++
Sbjct  481  LKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERGYLL  540

Query  540  KKGRSIRASDAAFTLIDAVPAAIADPGTTAVWEQALDMIEAGQLTLDVFLSKQAAWISQL  599
            KKGR++RASDAA  LIDAVPAAI+DPGTTAVWEQALDMIEAG++TL+ F++KQ++WI+QL
Sbjct  541  KKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWITQL  600

Query  600  IAQYGSMSLSIKLPHGPACPQCGAATRQRTGKSGPFWSCSRYPDCKGTLPVESG  653
            + QY + +L+IKLP+GPACP CG+ATRQRTGK+GPFWSC RYPDCKGTLPV++G
Sbjct  601  VQQYRAATLAIKLPEGPACPLCGSATRQRTGKTGPFWSCCRYPDCKGTLPVQNG  654

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  845 bits (3200),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 503/672 (75%), Positives = 606/672 (91%), Gaps = 4/672 (0%)

Query  1    MRLFLCEKPSQGKDIGRILGATQRGEGCLNGSGVTVTWCIGHLVEAAAPEVYDAALKRWS  60
            MRLFLCEKPSQGKDI+R+LGA QRG GC NG+G  VTWCIGHL+EAA+PE Y+   KRWS
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQYKRWS  60

Query  61   LEQLPIIPQQWRVEVKPQTATQFKVVKTLLAKATHLVIATDADREGELIAREIIDLCGYR  120
            LEQLPIIP++WRVE K+ TA+Q+K+VK L+++A++LVIATDADREGE+IAREIIDLCGYR
Sbjct  61   LEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGYR  120

Query  121  GPIARLWLSALNDASIRTALAKLRPSAETLPMYYSALARSRADWLVGMNLSRLFTVLGRQ  180
            GPI RLWLSALNDASIR AL+ L+PS+E+LP+Y +ALARSRADWLVGMNLSRLFT+LGRQ
Sbjct  121  GPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGRQ  180

Query  181  AGYDGVLSVGRVQTPTLKLVVDRDREIAAFVSVPYWAIDVSLSAGGQTFTAQWVAPDAST  240
            AGYDGVLSVGRVQTPTL LVV RDREIA FVSVP+W+I+V+LS+GG++F A W+A+D+ +
Sbjct  181  AGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGCS  240

Query  241  DDAGRCLqqpvaqqaaqqiraagsaqVVSVETERVREGPPLLFDLGTLQEVCSKQLGLDV  300
            DDAGRCLQQ+ AQQAA+++R AGSAQVV+V TERVRE+PPL FDLGTLQ+VCS+QL+LDV
Sbjct  241  DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALDV  300

Query  301  QETLEIAQALYETHKATTYPRSDSGYLPESMFAEVPTVLDSLLKTDPTLAPIMGQLDRAQ  360
            QETL+IAQALYETHKATTYPRSDSGYLPESM+AEVP+VL ++L TDP+L P++ QLDR+Q
Sbjct  301  QETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRTQ  360

Query  361  RSRAWNDSKVTAHHGIIPTLEPANLSAMSEKEQAVYRLIRAHYLAQFLPHHEFDRTIAEL  420
            RSRAWNDSKV+AHHGIIPTLEPANL+A+S+K  AVYRLIRAHYLAQFLPH EFDRT A+L
Sbjct  361  RSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQL  420

Query  421  SCGQQKLVATGKQVAAQGWHLVLAEPQADE-DGETIARSQVLPALREGLACQVAEAEVKA  479
             CG Q L A GKQV   GWH VLA P+AD+ DGE+++RSQVLPALREGL+CQV + ++KA
Sbjct  421  LCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLSCQVNHVDLKA  480

Query  480  LKTLPPKPYTQGELVKSMKGVARFVTDPRLKQKLKDTTGIGTEATRANIITGLLTRGYLV  539
            LKT PPKPYTQG+L+K+MKGVA++VTDPRLKQKLK+TTGIGTEATRA+II GLL RGYL+
Sbjct  481  LKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERGYLL  540

Query  540  KKGRSIRASDAALTLIDAVPAAIADPGTTAVWEQALDMIEAGQLTLDVFIGKQAAWISQL  599
            KKGR++RASDAA  LIDAVPAAI+DPGTTAVWEQALDMIEAG++TL+ F++KQ++WI+QL
Sbjct  541  KKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWITQL  600

Query  600  IAQYGSTSLSIKVPQGPACPQCGAPTRQRTGKSGPFWSCSRYPDCKGTLPVETG---TSK  656
            + QY +++L+IK+P+GPACP CG++TRQRTGK+GPFWSC RYPDCKGTLPV+ G   ++K
Sbjct  601  VQQYRAATLAIKLPEGPACPLCGSATRQRTGKTGPFWSCCRYPDCKGTLPVQNGRQASAK  660

Query  657  RGASRPRKSGRK  668
            R++SR  +   K
Sbjct  661  RSTSRKPRQIPK  672

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  844 bits (3194),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 504/672 (75%), Positives = 605/672 (91%), Gaps = 4/672 (0%)

Query  1    MRLFLCEKPSQGKDIGRILGATQRGEGCLNGSGVTVTWCIGHLVEAAAPEVYDAALKRWS  60
            MRLFLCEKPSQGKDI+R+LGA QRG GC NG+G  VTWCIGHL+EAA+PE Y+   KRWS
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQYKRWS  60

Query  61   LEQLPIIPQQWRVEVKPQTATQFKVVKTLLAKATHLVIATDADREGELIAREIIDLCGYR  120
            LEQLPIIP++WRVE K+ TA+Q+K+VK L+++A++LVIATDADREGE+IAREIIDLCGYR
Sbjct  61   LEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGYR  120

Query  121  GPIARLWLSALNDASIRTALAKLRPSAETLPMYYSALARSRADWLVGMNLSRLFTVLGRQ  180
            GPI RLWLSALNDASIR AL+ L+PS+E+LP+Y +ALARSRADWLVGMNLSRLFT+LGRQ
Sbjct  121  GPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGRQ  180

Query  181  AGYDGVLSVGRVQTPTLKLVVDRDREIAAFVSVPYWAIDVSLSAGGQTFTAQWVAPDAST  240
            AGYDGVLSVGRVQTPTL LVV RDREIA FVSVP+W+I+V+LS+GG++F A W+A+D+ +
Sbjct  181  AGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGCS  240

Query  241  DDAGRCLqqpvaqqaaqqiraagsaqVVSVETERVREGPPLLFDLGTLQEVCSKQLGLDV  300
            DDAGRCLQQ+ AQQAA+++R AGSAQVV+V TERVRE+PPL FDLGTLQ+VCS+QL+LDV
Sbjct  241  DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALDV  300

Query  301  QETLEIAQALYETHKATTYPRSDSGYLPESMFAEVPTVLDSLLKTDPTLAPIMGQLDRAQ  360
            QETL+IAQALYETHKATTYPRSDSGYLPESM+AEVP+VL ++L TDP+L P++ QLDR+Q
Sbjct  301  QETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRTQ  360

Query  361  RSRAWNDSKVTAHHGIIPTLEPANLSAMSEKEQAVYRLIRAHYLAQFLPHHEFDRTIAEL  420
            RSRAWNDSKV+AHHGIIPTLEPANL+A+S+K  AVYRLIRAHYLAQFLPH EFDRT A+L
Sbjct  361  RSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQL  420

Query  421  SCGQQKLVATGKQVAAQGWHLVLAEPQADE-DGETTARSQVLPALREGLACQVAEAEVKA  479
             CG Q L A GKQV   GWH VLA P+AD+ DGE+ +RSQVLPALREGL+CQV + ++KA
Sbjct  421  LCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLSCQVNHVDLKA  480

Query  480  LKTLPPKPYTQGELVKSMKGVARFVTDPRLKQKLKDTTGIGTEATRANIITGLLTRGYLV  539
            LKT PPKPYTQG+L+K+MKGVA++VTDPRLKQKLK+TTGIGTEATRA+II GLL RGYL+
Sbjct  481  LKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERGYLL  540

Query  540  KKGRSIRASDAALTLIDAVPAAIADPGTTAVWEQALDMIEAGQLTLDVFIGKQAAWISQL  599
            KKGR++RASDAA  LIDAVPAAI+DPGTTAVWEQALDMIEAG++TL+ F++KQ++WI+QL
Sbjct  541  KKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWITQL  600

Query  600  IVQYGSTSLSIKVPQGPACPQCGAPTRQRTGKTGPFWSCSRYPDCKGTLPVETG---TSK  656
            + QY +++L+IK+P+GPACP CG++TRQRTGKTGPFWSC RYPDCKGTLPV+ G   ++K
Sbjct  601  VQQYRAATLAIKLPEGPACPLCGSATRQRTGKTGPFWSCCRYPDCKGTLPVQNGRQASAK  660

Query  657  RGASRPRKSGRK  668
            R++SR  +   K
Sbjct  661  RSTSRKPRQIPK  672

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  840 bits (3182),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 519/653 (80%), Positives = 604/653 (93%), Gaps = 0/653 (0%)

Query  1    MRVFLCEKPSQGKDIARVLGAVQRGNGCYSGAGVVVTWCIGHLVEAVPPEGYGEQYKRWA  60
            MR+FLCEKPSQGKDIARVLGA QRG+GCY+GAG VVTWCIGHL+EA PPE+YGEQYKRW+
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQYKRWS  60

Query  61   IEQLPILPERWRVEPKAATAAQFKVVQQLVAKAGELVIATDADREGEMIAREIIDLCGYR  120
            +EQLPI+PERWRVEPKAATAAQ+K+V+QLV++A+ELVIATDADREGEMIAREIIDLCGYR
Sbjct  61   LEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGYR  120

Query  121  GPIQRLWLSALNDASIRKALGALKPSAETLPLYFSALARSRADWLIGMNLSRLFTLLGRQ  180
            GPIQRLWLSALNDASIRKALGALKPS+E+LPLY +ALARSRADWL+GMNLSRLFTLLGRQ
Sbjct  121  GPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGRQ  180

Query  181  AGYTGVLSVGRVQTPTLKLVVDRDREIARFVSMPYWAVDVLLSHAGQSFTASWIPPEGST  240
            AGY GVLSVGRVQTPTL LVV RDREIARFVS+P+W+++V LS +G+SF A+WI+++G +
Sbjct  181  AGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGCS  240

Query  241  DAAGRCLQQPvaqqaadriraardaqvvSVDTERVREAPPLPFDLGTLQEVCSKQLGLDV  300
            D AGRCLQQ+ AQQAADR+R A  AQVV+V TERVREAPPLPFDLGTLQ+VCS+QL+LDV
Sbjct  241  DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALDV  300

Query  301  QETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPTVLDSLVKTDPSLRPLIERLDRQQ  360
            QETLDIAQALYETHKATTYPRSDSGYLPESMLAEVP+VL +++ TDPSLRPL+E+LDR Q
Sbjct  301  QETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRTQ  360

Query  361  RSRAWNDGKVSAHHGIIPTLEPANLSAMNEKELAVYRLICAHYLAQFLPHHEFDRTVAQF  420
            RSRAWND+KVSAHHGIIPTLEPANL+A+++K LAVYRLI AHYLAQFLPH EFDRT AQ+
Sbjct  361  RSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQL  420

Query  421  SCGSQSLAAVGKQIAVTGWREVLATPGPDDADGEDAQRSQVLPALHAGLSCPVGKVDLKA  480
             CG+Q+L AVGKQ+ + GW++VLA P +D+ADGE   RSQVLPAL+ GLSC V  VDLKA
Sbjct  421  LCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLSCQVNHVDLKA  480

Query  481  LKTLPPKPYTQGELIKAMKTVAKFVTDPRLKQKLRDTTGIGTEATRANIINGLIGRGYLV  540
            LKT PPKPYTQG+LIKAMK VAK+VTDPRLKQKL++TTGIGTEATRA+II+GL+ RGYL+
Sbjct  481  LKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERGYLL  540

Query  541  KKGRAVRASDAAFTLIDAVPSAIADPGTTAVWEQALDMIEAGQMALDTFIEKQSVWVGQL  600
            KKGR+VRASDAA  LIDAVP+AI+DPGTTAVWEQALDMIEAG+M+L+TF+ KQS W+ QL
Sbjct  541  KKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWITQL  600

Query  601  VQQYRGATLSLKLppapacpqcgapmqqRTGKSGAFWSCSRYPDCKGTLPLES  653
            VQQYR+ATL++KLP +PACP CG++ +QRTGK+G+FWSC RYPDCKGTLP+++
Sbjct  601  VQQYRAATLAIKLPEGPACPLCGSATRQRTGKTGPFWSCCRYPDCKGTLPVQN  653

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  840 bits (3182),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 497/668 (75%), Positives = 605/668 (91%), Gaps = 4/668 (0%)

Query  1    MRLFLCEKPSQGKDIGRILGATQRGEGCLNGSGVTVTWCIGHLVEAAAPEVYDAALKRWS  60
            MRLFLCEKPSQGKDI+R+LGA QRG GC NG+G  VTWCIGHL+EAA+PE Y+   KRWS
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQYKRWS  60

Query  61   LEQLPIIPQQWRVEVKPQTATQFKVVKTLLAKATHLVIATDADREGELIAREIIDLCGYR  120
            LEQLPIIP++WRVE K+ TA+Q+K+VK L+++A++LVIATDADREGE+IAREIIDLCGYR
Sbjct  61   LEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGYR  120

Query  121  GPIERLWLSALNDASIRTALAKLRPSAETLPMYYSALARSRADWLVGMNLSRLFTVLGRQ  180
            GPI+RLWLSALNDASIR AL+ L+PS+E+LP+Y +ALARSRADWLVGMNLSRLFT+LGRQ
Sbjct  121  GPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGRQ  180

Query  181  AGYDGVLSVGRVQTPTLKLVVDRDREIAAFESVPYWAIDVSLSAGGQTFTAQWVAPDAST  240
            AGYDGVLSVGRVQTPTL LVV RDREIA F SVP+W+I+V+LS+GG++F A W+A+D+ +
Sbjct  181  AGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGCS  240

Query  241  DDAGRCLqqpvaqqaaqqiraagsaqVVSVETERVREGPPLLFDLGTLQEVCSKQLGLDV  300
            DDAGRCLQQ+ AQQAA+++R AGSAQVV+V TERVRE+PPL FDLGTLQ+VCS+QL+LDV
Sbjct  241  DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALDV  300

Query  301  QETLEIAQALYETHKATTYPRSDSGYLPESMFAEVPTVLDSLLKTDPSLRPIMEQLDRSV  360
            QETL+IAQALYETHKATTYPRSDSGYLPESM+AEVP+VL ++L TDPSLRP++EQLDR+ 
Sbjct  301  QETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRTQ  360

Query  361  RSRAWNDTKVSAHHGIIPTLEPANLSAMSEKEQAVYRLIRAHYLAQFLPHHEFDRTVAEL  420
            RSRAWND+KVSAHHGIIPTLEPANL+A+S+K  AVYRLIRAHYLAQFLPH EFDRT A+L
Sbjct  361  RSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQL  420

Query  421  FCGQQKLVATGKQVVAKGWRLVLAEPQADE-DGDGAARSQVLPALRDGMACQIAGADIKA  479
            +CG Q L A GKQV+  GW+ VLA P+AD+ DG++ +RSQVLPALR+G++CQ+   D+KA
Sbjct  421  LCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLSCQVNHVDLKA  480

Query  480  LKTMPPKPYTQGELVKAMKGVARFVTDPRLKQKLKDTTGIGTEATRANIISGLIARGYIV  539
            LKT PPKPYTQG+L+KAMKGVA++VTDPRLKQKLK+TTGIGTEATRA+II GL+ RGY++
Sbjct  481  LKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERGYLL  540

Query  540  KKGRSIRASDAAFTLIDAVPAAIADPGTTAVWEQALDMIEGGQLTLDVFIGKQAAWISQL  599
            KKGR++RASDAA  LIDAVPAAI+DPGTTAVWEQALDMIE+G++TL+ F++KQ++WI+QL
Sbjct  541  KKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWITQL  600

Query  600  IAQYGSTSLSIKVPQGPACPQCGAPTRQRTGKSGPFWSCSRYPDCKGTLPVATG---TSR  656
            + QY +++L+IK+P+GPACP CG++TRQRTGK+GPFWSC RYPDCKGTLPV  G   +++
Sbjct  601  VQQYRAATLAIKLPEGPACPLCGSATRQRTGKTGPFWSCCRYPDCKGTLPVQNGRQASAK  660

Query  657  RGASRPRR  664
            R++SR  R
Sbjct  661  RSTSRKPR  668

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  837 bits (3168),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 497/670 (75%), Positives = 601/670 (90%), Gaps = 5/670 (0%)

Query  1    MRLFLCEKPSQGKDIGRILGATQRGEGCLNGSGVTVTWCIGHLVEAAAPEVYDAALKRWS  60
            MRLFLCEKPSQGKDI+R+LGA QRG GC NG+G  VTWCIGHL+EAA+PE Y+   KRWS
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQYKRWS  60

Query  61   LEQLPIIPQQWRVEVKPKTATQFKVVKALLAKATHLVIATDADREGELIAREIIDLCGYR  120
            LEQLPIIP++WRVE K+ TA+Q+K+VK L+++A++LVIATDADREGE+IAREIIDLCGYR
Sbjct  61   LEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGYR  120

Query  121  GPIERLWLSALNDASIRTALAKLRPSAETLPMYYSALARSRADWLVGMNLSRLFTVLGRQ  180
            GPI+RLWLSALNDASIR AL+ L+PS+E+LP+Y +ALARSRADWLVGMNLSRLFT+LGRQ
Sbjct  121  GPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGRQ  180

Query  181  AGYDGVLSVGRVQTPTLKLVVDRDREIAAFVSVPYWAIDVSLSAGGQTFTAQWVAPDASA  240
            AGYDGVLSVGRVQTPTL LVV RDREIA FVSVP+W+I+V+LS+GG++F A W+A+D+ +
Sbjct  181  AGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGCS  240

Query  241  DDAGRCLqqpiaqqaaqqiraagsaqVVSVETERVREGPPLLFDLGTLQEVCSKQLGLDV  300
            DDAGRCLQQ+ AQQAA+++R AGSAQVV+V TERVRE+PPL FDLGTLQ+VCS+QL+LDV
Sbjct  241  DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALDV  300

Query  301  QETLEIAQALYETHKATTYPRSDSGYLPESMFAEVPTVLDSLLKTDPTLAPIMGQLDRTQ  360
            QETL+IAQALYETHKATTYPRSDSGYLPESM+AEVP+VL ++L TDP+L P++ QLDRTQ
Sbjct  301  QETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRTQ  360

Query  361  RSRAWNDSKVTAHHGIIPTLEPANLSAMSEKEQAVYRLIRAHYLAQFLPHHEFDRTVADL  420
            RSRAWNDSKV+AHHGIIPTLEPANL+A+S+K  AVYRLIRAHYLAQFLPH EFDRT A+L
Sbjct  361  RSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQL  420

Query  421  SCGQQKLVATGKQVVVKGWRLVLAEPEREGSADEDGDAPRSQVLPALRDGMACQVAGADI  480
             CG Q L A GKQV++ GW+ VLA PE + + +E    PRSQVLPALR+G++CQV   D+
Sbjct  421  LCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGE--AVPRSQVLPALREGLSCQVNHVDL  478

Query  481  KALKTMPPKPYTQGELVKAMKGVARFVTDPRLKQKLKDTTGIGTEATRANIISGLIARGY  540
            KALKT PPKPYTQG+L+KAMKGVA++VTDPRLKQKLK+TTGIGTEATRA+II GL+ RGY
Sbjct  479  KALKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERGY  538

Query  541  IVKKGRSIRASDAALTLIDAVPAAIADPGTTAVWEQALDMIEAGQLTLDVFIGKQAAWIS  600
            ++KKGR++RASDAA  LIDAVPAAI+DPGTTAVWEQALDMIEAG++TL+ F++KQ++WI+
Sbjct  539  LLKKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWIT  598

Query  601  QLIAQYGSTSLSIKVPQGPACPQCGAPTRQRTGKSGPFWSCSRYPACKGTLPVATG---T  657
            QL+ QY +++L+IK+P+GPACP CG++TRQRTGK+GPFWSC RYP CKGTLPV  G   +
Sbjct  599  QLVQQYRAATLAIKLPEGPACPLCGSATRQRTGKTGPFWSCCRYPDCKGTLPVQNGRQAS  658

Query  658  SRRGASRPRR  667
            ++R++SR  R
Sbjct  659  AKRSTSRKPR  668

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  835 bits (3161),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 494/654 (76%), Positives = 597/654 (92%), Gaps = 1/654 (0%)

Query  1    MRLFLCEKPSQGKDIGRILGATQRGEGCLNGSGVTITWCIGHLVEAAAPEVYDAALKRWS  60
            MRLFLCEKPSQGKDI+R+LGA QRG GC NG+G  +TWCIGHL+EAA+PE Y+   KRWS
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQYKRWS  60

Query  61   LEQLPIIPQQWRVEVKPKTATQFKVVKALLAKATHLVIATDADREGELIAREIIDLCGYR  120
            LEQLPIIP++WRVE K+ TA+Q+K+VK L+++A++LVIATDADREGE+IAREIIDLCGYR
Sbjct  61   LEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGYR  120

Query  121  GPIERLWLSALNDASIRTALGKLRPSSDTLPMYYSALARSRADWLVGMNLSRLFTLLGRQ  180
            GPI+RLWLSALNDASIR ALG L+PSS++LP+Y +ALARSRADWLVGMNLSRLFTLLGRQ
Sbjct  121  GPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGRQ  180

Query  181  AGYDGVLSVGRVQTPTLKLVVDRDREIAAFKSVPFWAIDVSLSAEGQAFAAQWVAPDDCT  240
            AGYDGVLSVGRVQTPTL LVV RDREIA F SVPFW+I+V+LS+ G++F A W+A+D+C+
Sbjct  181  AGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGCS  240

Query  241  DDAGRCLqqpvaqqaaqqiraagsaqVVSVGTERVREGPPLLFDLSTLQEVCSRQVGLDV  300
            DDAGRCLQQ+ AQQAA+++R AGSAQVV+V TERVRE+PPL FDL+TLQ+VCSRQ++LDV
Sbjct  241  DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALDV  300

Query  301  QETLQIAQALYETHKATTYPRSDSGYLPESMFAEVPIVLDSLLNTDPSLRPIMGQLDRSQ  360
            QETL+IAQALYETHKATTYPRSDSGYLPESM+AEVP VL ++L TDPSLRP++ QLDR+Q
Sbjct  301  QETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRTQ  360

Query  361  RSRAWNDGKVTAHHGIIPTLEPANLSALSEKELAVYRLIRAHYLAQFLPHHEFDRTVAEF  420
            RSRAWND+KV+AHHGIIPTLEPANL+A+S+K LAVYRLIRAHYLAQFLPH EFDRT A++
Sbjct  361  RSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQL  420

Query  421  SCGQQTLVATGKQVVVKGWRLVLAEPQADE-DGDDTARSQVLPPLREGLACQVAEVEIKA  479
             CG QTL A GKQV++ GW+ VLA P+AD+ DG+  +RSQVLP+LREGL+CQV +V++KA
Sbjct  421  LCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLSCQVNHVDLKA  480

Query  480  LKTMPAKPYTQGELVKSMKGIARFVTDPRLKQKLKDTTGIGTEATRANIISVLIARGYIV  539
            LKT P+KPYTQG+L+K+MKG+A++VTDPRLKQKLK+TTGIGTEATRA+II  L+ RGY++
Sbjct  481  LKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERGYLL  540

Query  540  KKGRSIRASDAAFTLIDAVPAAIADPGTTAVWEQALDMIEAGQLTLDVFLSKQAAWISQL  599
            KKGR++RASDAA  LIDAVPAAI+DPGTTAVWEQALDMIEAG++TL+ F++KQ++WI+QL
Sbjct  541  KKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWITQL  600

Query  600  IAQYGCVSLSIKLSHGPACPQCGAATRQRTGKSGPFWSCSRYPDCKGTLPVESG  653
            + QY   +L+IKL++GPACP CG+ATRQRTGK+GPFWSC RYPDCKGTLPV++G
Sbjct  601  VQQYRAATLAIKLPEGPACPLCGSATRQRTGKTGPFWSCCRYPDCKGTLPVQNG  654

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  834 bits (3156),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 511/672 (77%), Positives = 609/672 (91%), Gaps = 3/672 (0%)

Query  1    MRVVLCEKPSQGKDIARVLGATQRGNGCYTGSGLGVTWGIGHLIETAPPEAYGEQYKRWA  60
            MR+ LCEKPSQGKDIARVLGA QRG+GCY G+G  VTW IGHLIE+APPEAYGEQYKRW+
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQYKRWS  60

Query  61   LEPLPIIPQHWQVVVKAKTATQFKVVKQLLAQATDLVIATDADREGEMIARELIDYCGYR  120
            LE LPIIP++W+V  KA TA+Q+K+VKQL++QA++LVIATDADREGEMIARE+ID CGYR
Sbjct  61   LEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGYR  120

Query  121  GPIQRLWLSALNDASIRKALGALKPSGETLPLYYSALARSRADWLIGMNLSRLFTVLGRQ  180
            GPIQRLWLSALNDASIRKALGALKPS+E+LPLY +ALARSRADWL+GMNLSRLFT+LGRQ
Sbjct  121  GPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGRQ  180

Query  181  AGYSGVLSVGRVQTPTLKLVVDRDREIARFVSVPFWTIEVLLAHAGQSFVANWTPPAGCT  240
            AGY GVLSVGRVQTPTL LVV RDREIARFVSVPFW+IEV L+ +G+SF+A W ++ GC+
Sbjct  181  AGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGCS  240

Query  241  DDAGRCLQQPVAQQADERMRAAVSAQVVSVETERMREGPPLPFDLGTLQEVCSKQLGLDV  300
            DDAGRCLQQ+ AQQA +R+R A SAQVV+V TER+RE+PPLPFDLGTLQ+VCS+QL+LDV
Sbjct  241  DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALDV  300

Query  301  QETLDIAQSLYETHKATTYPRSDSGYLPENMLAEVPTVLDSLVKTDPSLRPLVAKLDPHQ  360
            QETLDIAQ+LYETHKATTYPRSDSGYLPE+MLAEVP+VL +++ TDPSLRPL+ +LD  Q
Sbjct  301  QETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRTQ  360

Query  361  RSRAWNDAKVTAHHGIIPTLEPANLSALNDKELAVYRLIRAHYLAQFLPHHEFDRTVAQF  420
            RSRAWND+KV+AHHGIIPTLEPANL+A++DK LAVYRLIRAHYLAQFLPH EFDRT AQ+
Sbjct  361  RSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQL  420

Query  421  ACAGQSLTVVGKQIVVTGWRQVLa-apapdepdedaQRSQVLPALHAGLSCPIGAVDLKA  479
             C+GQ+L  VGKQ+++ GW+QVLA + A +  +E   RSQVLPAL+ GLSC +  VDLKA
Sbjct  421  LCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLSCQVNHVDLKA  480

Query  480  LKTLPPKPYTQGELVKAMKGVARLVTDPRLKQKLKDTTGIGTEATRANIINgllgrgyll  539
            LKT PPKPYTQG+L+KAMKGVA+LVTDPRLKQKLK+TTGIGTEATRA+II+GLL RGYLL
Sbjct  481  LKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERGYLL  540

Query  540  kkgrAIRASDAAFTLIDAVPPAIADPGTTAVWEQALDMIEARQMTLDAFIAKQSAWVAQL  599
            KKGR++RASDAA  LIDAVP+AI+DPGTTAVWEQALDMIEA +MTL++F+AKQS+W++QL
Sbjct  541  KKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWITQL  600

Query  600  VQQYRTATLSIQLPPAPACPQCGSPMRQRTGKSGAFWSCSRYPDCKGTMAIESA--TGGK  657
            VQQYR+ATL+I+LP +PACP CGS+ RQRTGK+G+FWSC RYPDCKGT++++++  +++K
Sbjct  601  VQQYRAATLAIKLPEGPACPLCGSATRQRTGKTGPFWSCCRYPDCKGTLPVQNGRQASAK  660

Query  658  RSAPRKRRTAPK  669
            RS++RK R  PK
Sbjct  661  RSTSRKPRQIPK  672

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  830 bits (3141),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 523/653 (81%), Positives = 605/653 (93%), Gaps = 0/653 (0%)

Query  1    MRVFLCEKPSQGKDIARVLGAGQRGNGCYSGAGVVVTWCIGHLVEAVPPEGYGEQYKRWA  60
            MR+FLCEKPSQGKDIARVLGAGQRG+GCY+GAG VVTWCIGHL+EA PPE+YGEQYKRW+
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQYKRWS  60

Query  61   IEQLPILPERWRVEPKAATAAQFKVVQQLVAKAGELVIATDADREGEMIAREIIDLCGYR  120
            +EQLPI+PERWRVEPKAATAAQ+K+V+QLV++A+ELVIATDADREGEMIAREIIDLCGYR
Sbjct  61   LEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGYR  120

Query  121  GPIQRLWLSALNDASIRKALGALKPSAETLPLYFSALARSRADWLIGMNLSRLFTLLGRQ  180
            GPIQRLWLSALNDASIRKALGALKPS+E+LPLY +ALARSRADWL+GMNLSRLFTLLGRQ
Sbjct  121  GPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGRQ  180

Query  181  AGYMGVLSVGRVQTPTLKLVVDRDREIARFVSMPYWAVDVLLSHAGQSFTASWIPPEGST  240
            AGY GVLSVGRVQTPTL LVV RDREIARFVS+P+W+++V LS +G+SF A+WI+++G +
Sbjct  181  AGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGCS  240

Query  241  DAAGRCLQQPvaqqaadriraardaqvvSVDTERVREAPPLPFDLGTLQEVCSRQLGLDV  300
            D AGRCLQQ+ AQQAADR+R A  AQVV+V TERVREAPPLPFDLGTLQ+VCSRQL+LDV
Sbjct  241  DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALDV  300

Query  301  QETLDIAQALYETHKATTYPRSDSGYLPESMlaevlavldallaTDPSLRPLIGQLDRNQ  360
            QETLDIAQALYETHKATTYPRSDSGYLPESMLAEV AVL A+L+TDPSLRPL+ QLDR Q
Sbjct  301  QETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRTQ  360

Query  361  RSRAWNDGKVSAHHGIIPTLEPANLSAMNEKELAVYRLIRAHYLAQFLPHHEFDRTVAQF  420
            RSRAWND+KVSAHHGIIPTLEPANL+A+++K LAVYRLIRAHYLAQFLPH EFDRT AQ+
Sbjct  361  RSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQL  420

Query  421  SCGSQSLAAVGKQIAVIGWREVLATPGPDDADGEDAQRSQVLPALHAGLSCPVGKVDLKA  480
             CG+Q+L AVGKQ+ + GW++VLA P +D+ADGE   RSQVLPAL+ GLSC V  VDLKA
Sbjct  421  LCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLSCQVNHVDLKA  480

Query  481  LKTLPPKPYTQGELIKAMKTVAKFVTDPRLKQKLRDTTGIGTEATRANIINGLIGRGYLV  540
            LKT PPKPYTQG+LIKAMK VAK+VTDPRLKQKL++TTGIGTEATRA+II+GL+ RGYL+
Sbjct  481  LKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERGYLL  540

Query  541  KKGRAVRASDAAFTLIDAVPSAIADPGTTAVWEHALDMIEAGQMALDTFIEKQSVWVGQL  600
            KKGR+VRASDAA  LIDAVP+AI+DPGTTAVWE+ALDMIEAG+M+L+TF+ KQS W+ QL
Sbjct  541  KKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWITQL  600

Query  601  VQQYRGATLSLKLppapacpqcgapmqqRTGKSGAFWSCSRYPDCKGTLPIES  653
            VQQYR+ATL++KLP +PACP CG++ +QRTGK+G+FWSC RYPDCKGTLP+++
Sbjct  601  VQQYRAATLAIKLPEGPACPLCGSATRQRTGKTGPFWSCCRYPDCKGTLPVQN  653

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  830 bits (3144),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 495/653 (76%), Positives = 608/653 (94%), Gaps = 0/653 (0%)

Query  1    MRLFLCEKPSQGKDIGRLLGARQRGNGCLNGPGVVVTWCIGHLVEAAPPEAYDEQLKRWT  60
            MRLFLCEKPSQGKDI+R+LGA QRG+GC NG+G VVTWCIGHL+EAAPPEAY+EQ KRW+
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQYKRWS  60

Query  61   IEQLPIIPQHWRVEVKPKTAAQFKVVKDLLSKATELVIATDADREGELIAREIIDLCGYR  120
            +EQLPIIP++WRVE K+ TAAQ+K+VK+L+++A+ELVIATDADREGE+IAREIIDLCGYR
Sbjct  61   LEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGYR  120

Query  121  GPIQRLWLSALNDASIHAALGKLKPSGDTLPMYHSALARSRADWLVGMNLSRLFTLLGRR  180
            GPIQRLWLSALNDASI+ ALG LKPS+++LP+Y +ALARSRADWLVGMNLSRLFTLLGR+
Sbjct  121  GPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGRQ  180

Query  181  AGYDGVLSVGRVQTPTLRLVVDRDREIAAFVSVPFWSIEVALSCTGQTFTAQWLPPSAST  240
            AGYDGVLSVGRVQTPTL LVV RDREIA FVSVPFWSIEV+LS  G++F A W+++ + +
Sbjct  181  AGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGCS  240

Query  241  DDAGRCLQEPvaqqavqriraagaaqMVSVETERMREGAPLPFDLGTLQEVCSKQFGLDV  300
            DDAGRCLQ++ AQQA +R+R AG+AQ+V+V TER+RE++PLPFDLGTLQ+VCS+Q++LDV
Sbjct  241  DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALDV  300

Query  301  QETLEIAQSLYETHKATTYPRSDSGYLPESMHAEAPTVLDSLLKTDPSLRPIIDQLDRTQ  360
            QETL+IAQ+LYETHKATTYPRSDSGYLPESM AE P+VL ++L TDPSLRP+++QLDRTQ
Sbjct  301  QETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRTQ  360

Query  361  HSRAWNDAKVSAHHGIIPTLEPANLSAMSEKELAAYRLIRAHYLAQFLPPHEFDRTTARF  420
            +SRAWND+KVSAHHGIIPTLEPANL+A+S+K LA YRLIRAHYLAQFLP  EFDRTTA++
Sbjct  361  RSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQL  420

Query  421  SCGDQTLQAVGKHVVVPGWRLVLaepqpddagddaapRSQVLPALHQGLACQVAGVDLKA  480
             CG+QTLQAVGK+V++PGW+ VLA P++D+A+++A PRSQVLPAL++GL+CQV  VDLKA
Sbjct  421  LCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLSCQVNHVDLKA  480

Query  481  LKTLPPRPYTQGELVKAMKSVAKLVSDPRLKQKLKDSVGIGTEATRANIIGGLLNRGYLI  540
            LKT PP+PYTQG+L+KAMK+VAKLV+DPRLKQKLK++ GIGTEATRA+II GLL+RGYL+
Sbjct  481  LKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERGYLL  540

Query  541  KKGRAIRASDAAFTLIDTVPAAIADPGTTAVWEQALDMIETGQLALDTFIDKQAAWVTQL  600
            KKGR++RASDAA  LID+VPAAI+DPGTTAVWEQALDMIE+G+++L+TF+ KQ++W+TQL
Sbjct  541  KKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWITQL  600

Query  601  IAQYRGTSLSIKIPEGPACPQCGGATRQRSGKSGPFWSCAKYPDCKGTLPIES  653
            + QYR+++L+IK+PEGPACP CG+ATRQR+GK+GPFWSC +YPDCKGTLP+++
Sbjct  601  VQQYRAATLAIKLPEGPACPLCGSATRQRTGKTGPFWSCCRYPDCKGTLPVQN  653

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  794 bits (3004),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 472/678 (70%), Positives = 593/678 (88%), Gaps = 10/678 (1%)

Query  1    MRVVLCEKPSQGKDIARVLGAHRREAGCLGGPGITVTWGSGHLIEAAPPEAYGEHFQRWT  60
            MR+ LCEKPSQGKDIARVLGA +R +GC  G+G  VTW  GHLIEAAPPEAYGE+++RW+
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQYKRWS  60

Query  61   LETLPIVPPRWQWVVKARSAAQFKVVKRLLGEASELIIATDADREGEMIAREMIDYCGYR  120
            LE LPI+P RW+   KA +AAQ+K+VK+L+G+ASEL+IATDADREGEMIARE+ID CGYR
Sbjct  61   LEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGYR  120

Query  121  GPVQRLWLSALNDASIRKAFGALRASSETLSLYHCALARSRADWLVGINLTRLFTLLGRH  180
            GP+QRLWLSALNDASIRKA+GAL++SSE+L+LY  ALARSRADWLVG+NL+RLFTLLGR+
Sbjct  121  GPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGRQ  180

Query  181  AGHDGVLSVGRVQTPTLKLVVDRDREIAAFVPVPFWSIDVSLSAANVPFSAHWLAPRTAT  240
            AG DGVLSVGRVQTPTL LVV RDREIA FV+VPFWSI+V+LS++  +F A W+A+   +
Sbjct  181  AGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGCS  240

Query  241  DDAGRCLRQSVarhaadairaagtaQVVHTETERVREGPPLPFDLSTLQEVCSRRLGLEV  300
            DDAGRCL+Q+ A++AAD +R AG+AQVV   TERVRE+PPLPFDL+TLQ+VCSR+L+L+V
Sbjct  241  DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALDV  300

Query  301  QETLDIAQALYETHKATTYPRTDAGYLPENMLAEVPTVIQSLVKTDPALQPLIDRLDFRQ  360
            QETLDIAQALYETHKATTYPR+D+GYLPE+MLAEVP+V+ +++ TDP+L+PL+++LD  Q
Sbjct  301  QETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRTQ  360

Query  361  RSRAWNDAKITAHHAIIPTLEPADISAMSAKELAVYRLIRAHYLAQFLPHHEFDRTVVRF  420
            RSRAWND+K++AHH+IIPTLEPA+++A+S K LAVYRLIRAHYLAQFLPH EFDRT  ++
Sbjct  361  RSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQL  420

Query  421  RCGGETLQAVGKRIAVPGWQHAFSAPSLPHVAADGADTEGSDEAPREQMLPVLQEGISCQ  480
             CGG+TLQAVGK++ +PGW++ +++P         AD  +++  PR Q+LP L+EG+SCQ
Sbjct  421  LCGGQTLQAVGKQVIIPGWHQVLAGPE--------ADNADGEAVPRSQVLPALREGLSCQ  472

Query  481  VSALDLKSLSTKPPRPYTQGELVKAMKTVARLVTDPRLKQKLKDTTGIGTEATRANIISG  540
            V+ +DLK+L T+PP+PYTQG+L+KAMK VA+LVTDPRLKQKLK+TTGIGTEATRA+II G
Sbjct  473  VNHVDLKALKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKG  532

Query  541  LLSRGFLIRKGRAVRASDTAMMLIDAVPAAIADPGTTAIWEQALDMIEARQMGLESFVEK  600
            LL RG+L++KGR+VRASD+A  LIDAVPAAI+DPGTTA+WEQALDMIEA +M LE+FV K
Sbjct  533  LLERGYLLKKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAK  592

Query  601  QAAWVTQLVRQHLGTTLAIRSPEGPPCPLCGAATRQRTGRSGPFWSCSRYPDCKGTAPVA  660
            Q++W+TQLV+Q  ++TLAI+ PEGP+CPLCG+ATRQRTG++GPFWSC RYPDCKGT PV 
Sbjct  593  QSTWITQLVQQYRAATLAIKLPEGPACPLCGSATRQRTGKTGPFWSCCRYPDCKGTLPVQ  652

Query  661  PAQAGPDGQKRSRSRGAR  678
             ++ ++   KRS SR +R
Sbjct  653  NGRQASA--KRSTSRKPR  668

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  790 bits (2990),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 492/671 (74%), Positives = 587/671 (88%), Gaps = 5/671 (0%)

Query  1    MRLFLCEKPSQGKDIARVLGAKQRGDGCFHGDAITVTWCIGHLVEAAEPDAYGEQYKSWS  60
            MRLFLCEKPSQGKDIARVLGA QRG GC++G +  VTWCIGHL+EAA P+AYGEQYK WS
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQYKRWS  60

Query  61   IDQLPIIPDPWRIEIKPKTAAQLKIVKALIAQADELVIATDADREGEMIARELLELFSYR  120
            ++QLPIIP+ WR+E K+ TAAQLKIVK L++QA ELVIATDADREGEMIARE+++L +YR
Sbjct  61   LEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGYR  120

Query  121  GPIQRLWLSALNDASIRQALGALRPGSETLPLYHAALARSRADWLVGMNLSRLFTVLGRQ  180
            GPIQRLWLSALNDASIR+ALGAL+P+SE+LPLY AALARSRADWLVGMNLSRLFT+LGRQ
Sbjct  121  GPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGRQ  180

Query  181  AGYDGVLSVGRVQTPTLRLVVDRDREIARFVSVPFWTIELALSSNGQRFTAHWQAPDGST  240
            AGYDGVLSVGRVQTPTL LVV RDREIARFVSVPFW+IE++LS+ G+ F A W A+DG +
Sbjct  181  AGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGCS  240

Query  241  DDAGRCLQQPVAQSALATLQNARDVEVMSVDTERMREAPPLPFDLGTLQETCSRQLGLDV  300
            DDAGRCLQQ+ AQ A   L+ A   +V++V TER+REAPPLPFDLGTLQ+ CSRQL+LDV
Sbjct  241  DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALDV  300

Query  301  QETLDIAQALYETHKATTYPRTDCGYLPESMLADVPTILTALVRTDPSLLPLIATLDPTQ  360
            QETLDIAQALYETHKATTYPR+D GYLPESMLA+VP++L+A++ TDPSL PL+  LD TQ
Sbjct  301  QETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRTQ  360

Query  361  RSRAWNDGKITAHHGIIPTLEPANLAAMSDKEQAVYRLIRAHYLAQFLPHHEFDRTVAQF  420
            RSRAWND+K++AHHGIIPTLEPANLAA+SDK  AVYRLIRAHYLAQFLPH EFDRT AQ+
Sbjct  361  RSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQL  420

Query  421  ASGPERLTATGKQIAVIGWHSVLNEPASNEDTGDDSESPRSQTLPPLENGTRCAMEQVEL  480
              G + L A GKQ+ + GWH VL  P +++  G+    PRSQ LP+L +G  C +++V+L
Sbjct  421  LCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEA--VPRSQVLPALREGLSCQVNHVDL  478

Query  481  KALTTQPPRPYTQGELIKAMKGVAKLVSDPRLKQILKDTTGIGTEATRASIIQGLIARGY  540
            KAL TQPP+PYTQG+LIKAMKGVAKLV+DPRLKQ LK+TTGIGTEATRASII+GL+ RGY
Sbjct  479  KALKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERGY  538

Query  541  LLKKGRAVRGSDAAFTLidaipaaiadpgttaiWEQALERIEAGDMTLDAFVTRQATWVT  600
            LLKKGR+VR+SDAA  LIDA+PAAI+DPGTTA+WEQAL+ IEAGDMTL++FV++Q+TW+T
Sbjct  539  LLKKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWIT  598

Query  601  QLVQHYAQTTLAIKlppsppcplcgsTMRQRTSQRGPFWSCTRYPDCKGTLPVEKSK---  657
            QLVQ+Y  +TLAIKLP +P+CPLCGS+ RQRT++ GPFWSC RYPDCKGTLPV++++   
Sbjct  599  QLVQQYRAATLAIKLPEGPACPLCGSATRQRTGKTGPFWSCCRYPDCKGTLPVQNGRQAS  658

Query  658  TKRRAADTPRR  668
            +KR ++  PR+
Sbjct  659  AKRSTSRKPRQ  669

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  786 bits (2973),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 470/678 (70%), Positives = 591/678 (88%), Gaps = 13/678 (1%)

Query  1    MRVVLCEKPSQGKDIARVLGAHRREAGCLGGPGITVTWGSGHLIEAAPPEAYGEHFQRWT  60
            MR+ LCEKPSQGKDIARVLGA +R +GC  G+G  VTW  GHLIEAAPPEAYGE+++RW+
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQYKRWS  60

Query  61   L---PIVPPRWQWVVKARSAAQFKVVKRLLGEASELIIATDADREGEMIAREMIDYCGYR  117
            L   PI+P RW+   KA +AAQ+K+VK+L+G+ASEL+IATDADREGEMIARE+ID CGYR
Sbjct  61   LEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGYR  120

Query  118  GPVQRLWLSALNDASIRKAFGALRASSETLSLYHCALARSRADWLVGINLTRLFTLLGRH  177
            GP+QRLWLSALNDASIRKA+GAL++SSE+L+LY  ALARSRADWLVG+NL+RLFTLLGR+
Sbjct  121  GPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGRQ  180

Query  178  AGHDGVLSVGRVQTPTLKLVVDRDREIAAFVPVPFWSIDVSLSAANVPFSAHWLAPRTAT  237
            AG DGVLSVGRVQTPTL LVV RDREIA FV+VPFWSI+V+LS++  +F A W+A+   +
Sbjct  181  AGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGCS  240

Query  238  DDAGRCLRQSVarhaadairaagtaQVVHTETERVREGPPLPFDLSTLQEVCSRRLGLEV  297
            DDAGRCL+Q+ A++AAD +R AG+AQVV   TERVRE+PPLPFDL+TLQ+VCSR+L+L+V
Sbjct  241  DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALDV  300

Query  298  QETLDIAQALYETHKATTYPRTDAGYLPENMLAEVPTVIQSLVKTDPALQPLIDRLDFRQ  357
            QETLDIAQALYETHKATTYPR+D+GYLPE+MLAEVP+V+ +++ TDP+L+PL+++LD  Q
Sbjct  301  QETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRTQ  360

Query  358  RSRAWNDAKITAHHAIIPTLEPADISAMSAKELAVYRLIRAHYLAQFLPHHEFDRTVVRF  417
            RSRAWND+K++AHH+IIPTLEPA+++A+S K LAVYRLIRAHYLAQFLPH EFDRT  ++
Sbjct  361  RSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQL  420

Query  418  RCGGETLQAVGKRIAVPGWQHAFSAPSLPHVAADGADTEGSDEAPREQMLPVLQEGISCQ  477
             CGG+TLQAVGK++ +PGW++ +++P         AD  +++  PR Q+LP L+EG+SCQ
Sbjct  421  LCGGQTLQAVGKQVIIPGWHQVLAGPE--------ADNADGEAVPRSQVLPALREGLSCQ  472

Query  478  VSALDLKSLSTKPPRPYTQGELVKAMKTVARLVTDPRLKQKLKDTTGIGTEATRANIISG  537
            V+ +DLK+L T+PP+PYTQG+L+KAMK VA+LVTDPRLKQKLK+TTGIGTEATRA+II G
Sbjct  473  VNHVDLKALKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKG  532

Query  538  LLSRGFLIRKGRAVRASDTAMMLIDAVPAAIADPGTTAIWEQALDMIEARQMGLESFVEK  597
            LL RG+L++KGR+VRASD+A  LIDAVPAAI+DPGTTA+WEQALDMIEA +M LE+FV K
Sbjct  533  LLERGYLLKKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAK  592

Query  598  QAAWVTQLVRQHLGTTLAIRSPEGPPCPLCGAATRQRTGRSGPFWSCSRYPDCKGTAPVA  657
            Q++W+TQLV+Q  ++TLAI+ PEGP+CPLCG+ATRQRTG++GPFWSC RYPDCKGT PV 
Sbjct  593  QSTWITQLVQQYRAATLAIKLPEGPACPLCGSATRQRTGKTGPFWSCCRYPDCKGTLPVQ  652

Query  658  PAQAGPDGQKRSRSRGAR  675
             ++ ++   KRS SR +R
Sbjct  653  NGRQASA--KRSTSRKPR  668

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  765 bits (2896),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 465/680 (69%), Positives = 590/680 (87%), Gaps = 10/680 (1%)

Query  1    MRVVLCEKPSQGKDIARVLGARQREAGCLAGPGIKVTWGIGHLIEAAPPEAYGEHFQRWS  60
            MR+ LCEKPSQGKDIARVLGA QR +GC  G+G  VTW IGHLIEAAPPEAYGE+++RWS
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQYKRWS  60

Query  61   LETLPIVPQQWRWVVKADTASQFKVVQRLLAQASELIIATDADREGEMIARELIEYCGYR  120
            LE LPI+P++WR   KA TA+Q+K+V++L++QASEL+IATDADREGEMIARE+I+ CGYR
Sbjct  61   LEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGYR  120

Query  121  GPIQRLWLSALNDASIRKALGALRASHETLPLYHCALARSHADWLVGINLTRLFTLLGRK  180
            GPIQRLWLSALNDASIRKALGAL++S E+LPLY  ALARS+ADWLVG+NL+RLFTLLGR+
Sbjct  121  GPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGRQ  180

Query  181  AGFDGVLSVGRVQTPTLKLVADRDREIAAFVPVPFWSIEVSLSAGAQAFSAHWVPPATVT  240
            AG+DGVLSVGRVQTPTL LV  RDREIA FV+VPFWSIEV+LS+G+++F A W+++   +
Sbjct  181  AGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGCS  240

Query  241  DAAGRCLqqsaaqhaaaavrtaghaqVTGIDTERVQEGPPLPFDLSTLQEVCSRRLGLDV  300
            D AGRCLQQ++AQ+AA  +R AG AQV ++ TERV+E+PPLPFDL+TLQ+VCSR+L+LDV
Sbjct  241  DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALDV  300

Query  301  QETLDIAQALYETHKATTYPRTDAGYLPENMLTEVPTVIRSLLKTDPALQPLMQRLDLGQ  360
            QETLDIAQALYETHKATTYPR+D+GYLPE+ML+EVP+V+ ++L TDP+L+PL+++LD  Q
Sbjct  301  QETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRTQ  360

Query  361  RSRAWNATKIAAHHAIIPTLEPADLSKMSEKELAVYRLIRAHYLAQFLPHYAYDRTMVRL  420
            RSRAWN +K++AHH+IIPTLEPA+L+ +S+K LAVYRLIRAHYLAQFLPHY +DRT  +L
Sbjct  361  RSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQL  420

Query  421  ACGGQALQASGKQVVDAGWKAAFAAPSIPGAGAETPEAETDSEAPRDQALPTLHEGMACE  480
             CGGQ+LQA GKQV+ +GW   +A+P    A++E+         PR Q LP+L+EG++C+
Sbjct  421  LCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEA--------VPRSQVLPALREGLSCQ  472

Query  481  VRSLDLKSLYTKSPPPYTQGELVKAMKTVAKLVTDPRLKQTLRDTTGIGTEATRANIISG  540
            V  +DLK+L T++P PYTQG+L+KAMK VAKLVTDPRLKQ L++TTGIGTEATRA+II G
Sbjct  473  VNHVDLKALKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKG  532

Query  541  LLARGFLVRKGRVVRASKTAMTLIDAVPAAIADPGTTAIWEQALHMIEARTMDLDTFVSK  600
            LL RG+L++KGR VRAS +A  LIDAVPAAI+DPGTTA+WEQAL+MIEA  M L+TFV+K
Sbjct  533  LLERGYLLKKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAK  592

Query  601  QAAWVSQLVEQHREATLAIRVpagppcplcgaaTRKRTGKTGAFWSCSRYPDCKGTVAID  660
            Q++W++QLV+Q R ATLAI++P GP+CPLCG+ATR+RTGKTG+FWSC RYPDCKGT++++
Sbjct  593  QSTWITQLVQQYRAATLAIKLPEGPACPLCGSATRQRTGKTGPFWSCCRYPDCKGTLPVQ  652

Query  661  SA--EAGRRNGPRKPRAARK  678
            ++   +++R+ +RKPR   K
Sbjct  653  NGRQASAKRSTSRKPRQIPK  672

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  757 bits (2864),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 440/591 (75%), Positives = 543/591 (92%), Gaps = 2/591 (0%)

Query  1    MPIIPQHWRVEVKPKTATQFKVVKALLAKATQLVIATDADREGELIAREIIELCGYRGPI  60
            +PIIP++WRVE K+ TA+Q+K+VK L+++A++LVIATDADREGE+IAREII+LCGYRGPI
Sbjct  64   LPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGYRGPI  123

Query  61   ERLWLSALNDASIRAALGKLRPSAETLPMYHSALARSRADWLVGMNLSRLFTVLGRQAGY  120
            +RLWLSALNDASIR ALG L+PS+E+LP+Y +ALARSRADWLVGMNLSRLFT+LGRQAGY
Sbjct  124  QRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGRQAGY  183

Query  121  DGVLSVGRVQTPTLKLVVDRDREIAAFVSVPYWAIVVSLSAGVQAFTAHWVPPNACTDDA  180
            DGVLSVGRVQTPTL LVV RDREIA FVSVP+W+I V+LS+G ++F A W+++++C+DDA
Sbjct  184  DGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGCSDDA  243

Query  181  GRCLqqpvaqqamqqIRAAGSAHVVSVETERVREGPPLPFDLGTLQEVCSKQLGLDVQET  240
            GRCLQQ+ AQQA +++R AGSA+VV+V TERVRE+PPLPFDLGTLQ+VCS+QL+LDVQET
Sbjct  244  GRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALDVQET  303

Query  241  LEIAQALYETHKATTYPRSDSGYLPESMFAEVTTVLDSLLKTDPSLRSIIGQLDRLQRSR  300
            L+IAQALYETHKATTYPRSDSGYLPESM+AEV +VL ++L TDPSLR+++ QLDR QRSR
Sbjct  304  LDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRTQRSR  363

Query  301  AWNDGKVTAHHGIIPTLEPANLSAMSEKELAVYRLIRAHYLAQFLPHHEFDHTVAKLSCG  360
            AWND+KV+AHHGIIPTLEPANL+A+S+K LAVYRLIRAHYLAQFLPH EFD+T A+L CG
Sbjct  364  AWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQLLCG  423

Query  361  GQNLAATGKQVVTPGWRQVLAEPQSEdgdgdgdTAARAQVLPALHEGLACQVADIDLKAL  420
            GQ L A GKQV+ PGW+QVLA P+++  ++DG++ +R+QVLPAL+EGL+CQV ++DLKAL
Sbjct  424  GQTLQAVGKQVIIPGWHQVLAGPEAD--NADGEAVPRSQVLPALREGLSCQVNHVDLKAL  481

Query  421  KTLPPKPYTQGELVKSMKGVAKLVSDPRLKQKLKDTVGIGTEATRANIIGGLIARGYLVK  480
            KT PPKPYTQG+L+K+MKGVAKLV+DPRLKQKLK+T GIGTEATRA+II GL+ RGYL+K
Sbjct  482  KTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERGYLLK  541

Query  481  KGRAIRASDAAFTLIDAVPAAIADPGTTAVWEQALDMIEAGQLTLDVFIGKQAAWISQLI  540
            KGR++RASDAA  LIDAVPAAI+DPGTTAVWEQALDMIEAG++TL+ F++KQ++WI+QL+
Sbjct  542  KGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWITQLV  601

Query  541  AQYGNASLSIKAPQGPTCPQCGAPTRQRSSKSGPFWSCSRYPDCKGTLPVE  591
             QY  A+L+IK P+GP+CP CG++TRQR++K+GPFWSC RYPDCKGTLPV+
Sbjct  602  QQYRAATLAIKLPEGPACPLCGSATRQRTGKTGPFWSCCRYPDCKGTLPVQ  652

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  751 bits (2840),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 446/651 (69%), Positives = 568/651 (88%), Gaps = 1/651 (0%)

Query  1    MRLFLCEKPSQGKDIARVLGALRRGNGCYNGPGISVTWCIGHLVEAAPPEAYDERFKRWS  60
            MRLFLCEKPSQGKDIARVLGA +RG+GCYNG+G  VTWCIGHL+EAAPPEAY+E++KRWS
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQYKRWS  60

Query  61   LDQLPIVPTNWRVDVKADTAAQYKVVKQLLAKTTELVIATDADREGEMIAREILELCHYQ  120
            L+QLPI+P  WRV+ KA TAAQ K+VKQL+++++ELVIATDADREGEMIAREI++LC Y+
Sbjct  61   LEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGYR  120

Query  121  GSIRRLWLSALNEASIRKALTGLRPADETERLYHSALARSRADWLVGMNMSRLFTLLAQR  180
            G+I+RLWLSALN+ASIRKAL +L+P+ E+  LY +ALARSRADWLVGMN+SRLFTLL+++
Sbjct  121  GPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGRQ  180

Query  181  SGHHGVLSVGRVQTPTLRLVVDRDREIERFVPMHYWGIDVHLSYQEQLFLAQWVAPDCAT  240
            +G +GVLSVGRVQTPTL LVV RDREI RFV++ +W+I+V LS   + FLA W+A+D  +
Sbjct  181  AGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGCS  240

Query  241  DDAGRCIRQAMAQQALQSVRQAQRAQVLDMQMDRIREAPPLPFDLGTLQEVCSRRFGLGV  300
            DDAGRC++QA AQQA + +R A  AQV+ +  +R+REAPPLPFDLGTLQ+VCSR+++L+V
Sbjct  241  DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALDV  300

Query  301  QQTLEIAQSLYETHKATTYPRSDSGYLPESMWDEASTVLDALIISDPSVEALVQSVNRQQ  360
            Q+TL+IAQ+LYETHKATTYPRSDSGYLPESM  E ++VL A++ +DPS+ +L++ ++R Q
Sbjct  301  QETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRTQ  360

Query  361  RSRAWNDSKVSAHHGIIPTLEPFQIEALSEKERAVYELIRAHYLAQFLPHHEYDRSCALF  420
            RSRAWNDSKVSAHHGIIPTLEP ++ A+S+K  AVY LIRAHYLAQFLPH E+DR+ A +
Sbjct  361  RSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQL  420

Query  421  TCGGHTLRAHGKQIVASGWHRALA-PdsttsdddsAQRNQILPPLSTGSDCNVSQVELRT  479
             CGG+TL+A GKQ++ +GWH+ LA P++  +D+++  R+Q+LP+L  G  C+V++V+L++
Sbjct  421  LCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLSCQVNHVDLKA  480

Query  480  LKTQAPKALTQGELIKAMKGVAKLVTDPRLKRTLKETTGIGTEATRANIISGLLNRGYLY  539
            LKTQ+PK+ TQG+LIKAMKGVAKLVTDPRLK+ LKETTGIGTEATRA+II GLL+RGYL 
Sbjct  481  LKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERGYLL  540

Query  540  MKGRSVRASDAAFTLidavpaaiadpattaIWEQAFDMIENGQMTLDCFIAKQTAWITQL  599
             KGR+VRASDAA  LIDAVPAAI+DP+TTA+WEQA+DMIE G+MTL+ F+AKQ++WITQL
Sbjct  541  KKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWITQL  600

Query  600  VEHYRTTTLLIHTPGGPNCPLCGASMRQRQGKHGSFWSCSRYPECKGALPV  650
            V++YR++TL I  P GP CPLCG++ RQR GK G+FWSC RYP+CKG+LPV
Sbjct  601  VQQYRAATLAIKLPEGPACPLCGSATRQRTGKTGPFWSCCRYPDCKGTLPV  651

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  748 bits (2829),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 423/654 (65%), Positives = 552/654 (85%), Gaps = 3/654 (0%)

Query  1    MRLFLCEKPSQGRDIAKVLGATRRGDGCLIGTDSTVTWCIGHLLETAPPEAYGAQYKSWS  60
            MRLFLCEKPSQG+DIA+VLGA +RG GC  G+++ VTWCIGHL+E+APPEAYG QYK WS
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQYKRWS  60

Query  61   LDHLPIIPAQWQVEVKSKTAAQFKIIKRLLSEASSVVIATDADREGEMIARELLELCRYR  120
            L++LPIIP +W+VE K+ TAAQ+KI+K+L+++AS +VIATDADREGEMIARE+++LC YR
Sbjct  61   LEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGYR  120

Query  121  GPVLRLWLSALNEASIRKALSSLKSGQVTFPLYHSALARSRADWLIGMNLSRLFTLLGRR  180
            GP+ RLWLSALN+ASIRKAL++LK++  ++PLY +ALARSRADWL+GMNLSRLFTLLGR+
Sbjct  121  GPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGRQ  180

Query  181  AGYDGVLSVGRVQTPTLRLVVDRDRAIASFVPVPYWTVDVHLSSMGQRFIASWLPPRSGR  240
            AGYDGVLSVGRVQTPTL LVV RDR IA FV+VP+W+++V LS+ G+ F+A+W+++ +  
Sbjct  181  AGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGCS  240

Query  241  DEAGRCLQQALAHHAVQTITGEKSATVLSLQTEQLREPPPLPFDLSTLQEVCSRKLGLGV  300
            D+AGRCLQQA A++A + +    SA V+++ TE++RE+PPLPFDL+TLQ+VCSR+L+L+V
Sbjct  241  DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALDV  300

Query  301  QETLNIAQALYETHKATTYPRSDCRYLPESMFNEAPAVLDALLKTDPALRPAFGSLDRSL  360
            QETL+IAQALYETHKATTYPRSD  YLPESM+ E PAVL A+L TDP+LRP +  LDR+ 
Sbjct  301  QETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRTQ  360

Query  361  RARVWNNAKVTAHHGIIPTTEPANLVRMSEQERQVYELIRSHYLAQFLPHHEFDRTQVEL  420
            R+R WN++KV+AHHGIIPT EPANL  +S++   VY LIR+HYLAQFLPH EFDRT  +L
Sbjct  361  RSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQL  420

Query  421  ECSKERLTAVGKQILIQGWKGLLT---ENTEDDEPSQKHQVLPVLQQGTQCAVNDVELKS  477
             C+ + L AVGKQ++I GW  +L+    +  D+E+  + QVLP L++G  C VN+V+LK+
Sbjct  421  LCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLSCQVNHVDLKA  480

Query  478  MRTVAPKPLTEGDLIKAMKNVAKLVNDPRLKQKLRDTTGIGTEATRAGIIKGLVDRGYLL  537
            ++T +PKP T+GDLIKAMK VAKLV DPRLKQKL++TTGIGTEATRA+IIKGL++RGYLL
Sbjct  481  LKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERGYLL  540

Query  538  KKKRALMASAAAHTLIEAAPTAVADPGMTAIWEQALDEIEAGRLTLDAFVAKQANWIAQL  597
            KK R++ AS AA  LI+A P+A++DPG TA+WEQALD IEAG +TL++FVAKQ+ WI+QL
Sbjct  541  KKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWITQL  600

Query  598  VAHYRSHTLAIAVETSPSCPMCNASMLRRKGKSGPFWSCSCYPDCKGTVSISKD  651
            V +YR+ TLAI +  +P+CP+C ++  +R GK+GPFWSC  YPDCKGT+++ ++
Sbjct  601  VQQYRAATLAIKLPEGPACPLCGSATRQRTGKTGPFWSCCRYPDCKGTLPVQNG  654

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  736 bits (2783),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 425/654 (65%), Positives = 553/654 (85%), Gaps = 3/654 (0%)

Query  1    MRLFLCEKPSQGRDIATVLGATRRGDGCLIGTETTVTWCIGHLLETAPPEAYGIQYKNWS  60
            MRLFLCEKPSQG+DIA VLGA +RG GC  G+ T VTWCIGHL+E+APPEAYG QYK WS
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQYKRWS  60

Query  61   LDHLPIIPAQWKVEVKHKTAAQFKVIKRLLSEASAVVIATDADREGEMIARELLELCNYR  120
            L++LPIIP +W+VE K  TAAQ+K++K+L+++AS +VIATDADREGEMIARE+++LC YR
Sbjct  61   LEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGYR  120

Query  121  GPVERLWLSALNEVSILKALSSLKSGQETFPLYHSALARSRADWLIGMNLSRLFTLLGRR  180
            GP++RLWLSALN+ SI KAL++LK++ E++PLY +ALARSRADWL+GMNLSRLFTLLGR+
Sbjct  121  GPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGRQ  180

Query  181  AGYDGVLSVGRVQTPTLRLVVDRDRAIASFVSVPYWDVEVHLSFMGQSFIASWLPPSSGR  240
            AGYDGVLSVGRVQTPTL LVV RDR IA FVSVP+W +EV LS  G+SF+A+W+++ +  
Sbjct  181  AGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGCS  240

Query  241  DEACRCLQQALARHAGQTITDGKTATVLSLQTEHFREPPPLPFDLSTLQEVCSRKLGLGV  300
            D+A RCLQQA A++A++ +  + +A V+++ TE+ RE+PPLPFDL+TLQ+VCSR+L+L+V
Sbjct  241  DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALDV  300

Query  301  QETLNIAQALYETHKATTYPRSDCRYLPASMFDEVPTVFDALLKTDSALQPAFEKLDRSL  360
            QETL+IAQALYETHKATTYPRSD  YLP SM+ EVP+V+ A+L TD++L+P +E+LDR+ 
Sbjct  301  QETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRTQ  360

Query  361  RSRAWNDAKATAHHGIIPTTEPANLARMSEQERQVYEQIRNHYLAQFLPHHEFDRTQVEL  420
            RSRAWND+K +AHHGIIPT EPANLA +S++   VY  IR HYLAQFLPH EFDRT  +L
Sbjct  361  RSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQL  420

Query  421  ECGKERLTAVGKQILVQSWKGLLYD---NTEDDEPSQKFQVLPVLQQGTQCAVNDVELKS  477
             CG + L AVGKQ+++ +W  +L +   +  D+E+  + QVLP L++G  C VN+V+LK+
Sbjct  421  LCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLSCQVNHVDLKA  480

Query  478  MRTTAPKPLTEGDLIKAMKNVAKLVNDPRLKQKLRDTTGIGTEATRAGIIKGLIDRGYLL  537
            ++T +PKP T+GDLIKAMK VAKLV DPRLKQKL++TTGIGTEATRA+IIKGL++RGYLL
Sbjct  481  LKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERGYLL  540

Query  538  KKKRALMASAAAHTLIEAVPAAIADPGMTAIWEQALDEIEAGRLSLDAFVAKQASWIAQL  597
            KK R++ AS AA  LI+AVPAAI+DPG TA+WEQALD IEAG ++L++FVAKQ++WI+QL
Sbjct  541  KKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWITQL  600

Query  598  VEHCRALTLALPVETGPACPICNASMLRRTGKSGAFWSCSHYPDCKGTVPISKD  651
            V++ RA TLA+ +  GPACP+C ++  +RTGK+G+FWSC +YPDCKGT+P+ ++
Sbjct  601  VQQYRAATLAIKLPEGPACPLCGSATRQRTGKTGPFWSCCRYPDCKGTLPVQNG  654

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  735 bits (2782),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 422/655 (65%), Positives = 556/655 (85%), Gaps = 4/655 (0%)

Query  1    MRLFLCEKPSQGRDIAKVLGASRRGDGCLIGRETTVTWCIGHLLETAPPEAYGDQYKTWS  60
            MRLFLCEKPSQG+DIA+VLGA++RG GC  G  T VTWCIGHL+E+APPEAYG+QYK WS
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQYKRWS  60

Query  61   LDHLPIIPAQWRVEVKPKTVAQFKIIKHLLSEATTVVIATDADREGEMIARELLELCNYR  120
            L++LPIIP +WRVE K+ T AQ+KI+K+L+++A+ +VIATDADREGEMIARE+++LC YR
Sbjct  61   LEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGYR  120

Query  121  GSVERLWLSALNEASIRKALSSLKSSQETFPLYHSALARSRADWLIGMNLSRLFTLLGRR  180
            G+++RLWLSALN+ASIRKAL++LK+S E++PLY +ALARSRADWL+GMNLSRLFTLLGR+
Sbjct  121  GPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGRQ  180

Query  181  AGYGAVLSVGRVQTPTLRLVVERDRAIASFVSVPYWVVNAHLSSMGQQPFIASWIPPSSG  240
            AGY++VLSVGRVQTPTL LVV RDR IA FVSVP+W ++  LS+ G ++F+A+WI++ + 
Sbjct  181  AGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLST-GGHSFLATWIAADGC  239

Query  241  RDEAGRClqqalasqalqaisssKTATVVSLRTEHLREAPPLPFDLSTLQEVCSRKLGLG  300
             D+AGRCLQQA A QA + +  + +A VV++ TE++REAPPLPFDL+TLQ+VCSR+L+L+
Sbjct  240  SDDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALD  299

Query  301  AQETLNIAQALYETHKATSYPRSDCRYLPESMFNEVAAVFDALLRMDPALRPALGSIDQS  360
             QETL+IAQALYETHKAT+YPRSD  YLPESM+ EV+AV+ A+L  DP+LRP L  +D++
Sbjct  300  VQETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRT  359

Query  361  LRSRAWNDAKVTAHHGIIPTTEPANLGRMSEQERQVYELIRSHYLAQFLPHHEFDRTEVE  420
             RSRAWND+KV+AHHGIIPT EPANL+ +S++   VY LIR+HYLAQFLPH EFDRT  +
Sbjct  360  QRSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQ  419

Query  421  LECSAERLTAVGKQILVQGWKGLLSD---NPDDDEPSQKSQVLPALQQGRQCAVDDVELK  477
            L C+++ L AVGKQ+++ GW  +L++   +  D+E+  +SQVLPAL++G  C V++V+LK
Sbjct  420  LLCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLSCQVNHVDLK  479

Query  478  SMRTAAPKSLTEGDLIKAMKNVAKLVNDPRLKQKLRDTTGIGTEATRAGIIKGLIDRGYL  537
            +++T +PK+ T+GDLIKAMK VAKLV DPRLKQKL++TTGIGTEATRA+IIKGL++RGYL
Sbjct  480  ALKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERGYL  539

Query  538  LKKKRALMASATAHTLIEAVPAAVADPGMTAIWEQALDEIEAGRLSLDAFVAKQAHWITQ  597
            LKK R++ AS +A  LI+AVPAA++DPG TA+WEQALD IEAG ++L++FVAKQ+ WITQ
Sbjct  540  LKKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWITQ  599

Query  598  LIANCGALTLSVPVEAGPVCPICNASMLRRKGKSGPFWSCSHYPDCKGTVPISKG  652
            L+ +  A TL++ +  GP CP+C ++  +R GK+GPFWSC +YPDCKGT+P+ +G
Sbjct  600  LVQQYRAATLAIKLPEGPACPLCGSATRQRTGKTGPFWSCCRYPDCKGTLPVQNG  654

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  734 bits (2776),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 447/586 (77%), Positives = 535/586 (92%), Gaps = 4/586 (0%)

Query  33   KVVKALLAKATHLVIATDADREGELIAREIIDLCGYRGPIERLWLSALNDASIRTALGKL  92
            K+VK L+++A++LVIATDADREGE+IAREIIDLCGYRGPI+RLWLSALNDASIR ALG L
Sbjct  84   KIVKQLVGQASELVIATDADREGEMIAREIIDLCGYRGPIQRLWLSALNDASIRKALGAL  143

Query  93   RPSSDTLPMYYSALARSRADWLVGMNLSRLFTVLGLQAGYDGVLSVGRVQTPTLKLVVDR  152
            +PSS++LP+Y +ALARSRADWLVGMNLSRLFT+LG QAGYDGVLSVGRVQTPTL LVV R
Sbjct  144  KPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGRQAGYDGVLSVGRVQTPTLALVVTR  203

Query  153  DREIAAFKSVPFWAIDVSLSAGGQAFSAQWVPPDGCTDDAGRCLqqpiaqqaaqqiraas  212
            DREIA F SVPFW+I+V+LS+GG++F A W+++DGC+DDAGRCLQQ+ AQQAA+++R A+
Sbjct  204  DREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGCSDDAGRCLQQATAQQAADRLRVAG  263

Query  213  saqVVSVETERVREGPPLLFDLGTLQEVCSKQLGLDVQETLEIAQALYETHKATTYPRSD  272
            SAQVV+V TERVRE+PPL FDLGTLQ+VCS+QL+LDVQETL+IAQALYETHKATTYPRSD
Sbjct  264  SAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALDVQETLDIAQALYETHKATTYPRSD  323

Query  273  SGYLPESMFAEVPTVLDSLLKTDPSLRPIMGQLDRSQRSRAWNDGKVTAHHGIIPTLEPA  332
            SGYLPESM+AEVP+VL ++L TDPSLRP++ QLDR+QRSRAWND+KV+AHHGIIPTLEPA
Sbjct  324  SGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRTQRSRAWNDSKVSAHHGIIPTLEPA  383

Query  333  NLSAMSEKELAVYRLIRAHYLAQFLPHHEFDRTIAELSCGQQKLVATGKQVAAQGWHLVL  392
            NL+A+S+K LAVYRLIRAHYLAQFLPH EFDRT A+L CG Q L A GKQV   GWH VL
Sbjct  384  NLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQLLCGGQTLQAVGKQVIIPGWHQVL  443

Query  393  AEPQADE-DGETTARSQVLPALREGLACQVAEAEVKALKTLPPKPYTQGELVKSMKGVAR  451
            A P+AD+ DGE+ +RSQVLPALREGL+CQV + ++KALKT PPKPYTQG+L+K+MKGVA+
Sbjct  444  AGPEADNADGEAVPRSQVLPALREGLSCQVNHVDLKALKTQPPKPYTQGDLIKAMKGVAK  503

Query  452  FVTDPRLKQKLKDTTGIGTEATRANIITGLLTRGYLVKKGRSIRASDAAFTLIDAVPAAI  511
            +VTDPRLKQKLK+TTGIGTEATRA+II GLL RGYL+KKGR++RASDAA  LIDAVPAAI
Sbjct  504  LVTDPRLKQKLKETTGIGTEATRASIIKGLLERGYLLKKGRTVRASDAAGRLIDAVPAAI  563

Query  512  ADPGTTAVWEQALDMIEAGQLTLDVFIGKQAAWISQLIVQYGSTSLSIKVPQGPACPQCG  571
            +DPGTTAVWEQALDMIEAG++TL+ F++KQ++WI+QL+ QY +++L+IK+P+GPACP CG
Sbjct  564  TDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWITQLVQQYRAATLAIKLPEGPACPLCG  623

Query  572  APTRQRTGKTGPFWSCSRYPDCKGTLPVDSGTSKRGASRPRSSGRK  617
            ++TRQRTGKTGPFWSC RYPDCKGTLPV++G   R AS  RS++RK
Sbjct  624  SATRQRTGKTGPFWSCCRYPDCKGTLPVQNG---RQASAKRSTSRK  666

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  723 bits (2736),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 419/652 (65%), Positives = 544/652 (84%), Gaps = 2/652 (0%)

Query  1    MRLYLCEKPSQGKDIAAVLGAKTRGDGCIKGNGVAVTWGIGHLLETAPPDAYGEHLKNWS  60
            MRL+LCEKPSQGKDIA VLGA  RG GC +G G  VTW IGHL+E+APP+AYGE+ K WS
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQYKRWS  60

Query  61   LDTLPILPAEWKVLVKPKTASQFKIVKQLLKQATELVIATDADREGEMIARELIEYCGYR  120
            L+ LPI+P  W+V  K+ TA+Q+KIVKQL+ QA+ELVIATDADREGEMIARE+I+ CGYR
Sbjct  61   LEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGYR  120

Query  121  GPIQRLWLSALNEASIRQALNTVKQGSETYPLYLSALARSRADWLIGMNFSRLFTLLGRQ  180
            GPIQRLWLSALN+ASIR+AL ++K +SE+ PLY +ALARSRADWL+GMN+SRLFTLLGRQ
Sbjct  121  GPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGRQ  180

Query  181  AGYTGVLSVGRVQTPTLRLVVDRDRDISNFIPKPFWSVEVQLWTAGQSFLAKWVADEYLV  240
            AGY GVLSVGRVQTPTL LVV RDR+I+ F++ PFWS+EV L T+G+SFLA W+A +   
Sbjct  181  AGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGCS  240

Query  241  DEEGRCLDqaaaaaalaalkssqaasTVSVDTKRGKDPAPLPFDLSTLQEVCSAKFGMGV  300
            D+ GRCL+QA+A  A   L+ + +A  V+V T R ++++PLPFDL+TLQ+VCS +++++V
Sbjct  241  DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALDV  300

Query  301  QETLDVAQSLYETHKATTYPRTDCGYLPESMFDEVPMVLDALNRTDPSIGKTLQLIDPEQ  360
            QETLD+AQ+LYETHKATTYPR+D GYLPESM+ EVP VL A+  TDPS+   L+ +D  Q
Sbjct  301  QETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRTQ  360

Query  361  RSRAWNDKKITGPHHGIIPTLEPANLSAMSEKERKVYELIRAHFLAQFLPTHEYDRTVAT  420
            RSRAWND K+++ HHGIIPTLEPANL+A+S+K   VY LIRAH+LAQFLP  E+DRT A 
Sbjct  361  RSRAWNDSKVSA-HHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQ  419

Query  421  FECNAVLLQAVGKRIVIPGW-KVLFSASSEEEANDSGGRSQILPVLQIGTRCDVQDLHLK  479
            + C +  LQAVGK+++IPGW +VL ++ +++   ++  RSQ+LP L+ G  C+V++++LK
Sbjct  420  LLCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLSCQVNHVDLK  479

Query  480  SLKTEPPKAYTEGTLIKAMKTIAKLVKDPRLAQKLKETTGIGTEATRAGTIQGLIDRGSL  539
            +LKT+PPK+YT+G LIKAMK +AKLV DPRL QKLKETTGIGTEATRA+ I+GL++RG L
Sbjct  480  ALKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERGYL  539

Query  540  IKKGSALRATEAAFSLIDAVPPAVADPGTTAIWEQALTMIEQGTLTLDDFIARQSSWITR  599
            +KKG ++RA++AA  LIDAVP+A++DPGTTA+WEQAL MIE G +TL+ F+A+QS+WIT+
Sbjct  540  LKKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWITQ  599

Query  600  LVEQYKGTTLSIKVPEGPKCPLCSAKTSQRKGSSGVFWACSRYPECKGTVNI  651
            LV+QY+++TL+IK+PEGP CPLC++ T QR G +G FW+C RYP+CKGT+ +
Sbjct  600  LVQQYRAATLAIKLPEGPACPLCGSATRQRTGKTGPFWSCCRYPDCKGTLPV  651

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  670 bits (2533),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 393/611 (65%), Positives = 514/611 (85%), Gaps = 1/611 (0%)

Query  1    MRLFLCEKPSQAKDIAKVLGANRKGDGCWQGTDICVTWCIGHLLETAPPDSYDERYKRWN  60
            MRLFLCEKPSQ+KDIA+VLGA ++G GC +G++  VTWCIGHL+E+APP++Y+E+YKRW+
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQYKRWS  60

Query  61   LADLPIIPDKWKMLVKPKTASQFKAVKRLLGEARELVIATDADREGEMIARELVEHCRYR  120
            L +LPIIP++W++  K+ TA+Q+K VK+L+G+A ELVIATDADREGEMIARE+++ C YR
Sbjct  61   LEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGYR  120

Query  121  GPVQRLWLSALDDASIRKALARLLPGHETFNLYHSALGRSRADWLIGMNMSRLFTLLGRQ  180
            GP+QRLWLSAL+DASIRKAL+ L P+ E++ LY +AL+RSRADWL+GMN+SRLFTLLGRQ
Sbjct  121  GPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGRQ  180

Query  181  SGYQGVLPVGRVQTPTLRLVVDRDRSIANFVPVPFWAIDVQLEHAGQRFNAQWRAPEDAC  240
            +GY+GVL+VGRVQTPTL LVV RDR IA FV+VPFW+I+V L  +G+ F A W A+++  
Sbjct  181  AGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGCS  240

Query  241  DDQGRCLKQDLAQRAATDIGHAGTARAVKVATERVREAAPLPFDLGTLQELCSKKFGLGA  300
            DD GRCL+Q  AQ+AA  +  AG+A+ V V+TERVREA+PLPFDLGTLQ++CS++++L+ 
Sbjct  241  DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALDV  300

Query  301  QETLDIAQALYETHKLITYPRSDCGYLPQSQHAEAPAILAALQRADASLAPLQPYLEPQR  360
            QETLDIAQALYETHK  TYPRSD GYLP+S  AE PA+LAA+  +D+SL PL   L+  +
Sbjct  301  QETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRTQ  360

Query  361  RSRAWNDAKVSAHHGIIPTAAASDPSRLPAKHKAVYTLIRARYLAQFLPNHEYDRTQADF  420
            RSRAWND+KVSAHHGIIPT  +++ + ++ K  AVY LIRA+YLAQFLP+ E+DRT A++
Sbjct  361  RSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQL  420

Query  421  DCAGHALRAVGKQIVEPGWRRALPEA-LTPAKGREAPPAQVLPALREGQDCNVNGLQLKD  479
             C+G++L+AVGKQ++ PGW++ L+ +    A G   P +QVLPALREG  C+VN ++LK 
Sbjct  421  LCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLSCQVNHVDLKA  480

Query  480  LWTQPPKPFTEGDLIKAMKNVAKLVDDPRLKQKLKETTGIGTEATRASIIQGLLDRGYLV  539
            L TQPPKP+T+GDLIKAMK VAKLV DPRLKQKLKETTGIGTEATRASII+GLL+RGYL+
Sbjct  481  LKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERGYLL  540

Query  540  KNGKALSATPAAFSLIDAVPRAIADPGTTAIWEQALDMVQSGEMPLEEFVARQSAWMGKL  599
            K+G+++ A+ AA  LIDAVP AI+DPGTTA+WEQALDM+++G+M LE FVA+QS+W+ +L
Sbjct  541  KKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWITQL  600

Query  600  VERCSGMRMTI  610
            V++  +  ++I
Sbjct  601  VQQYRAATLAI  611

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  670 bits (2535),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 394/611 (65%), Positives = 515/611 (85%), Gaps = 1/611 (0%)

Query  1    MRLFLCEKPSQAKDIAKVLGANRKGDGCWQGTDICVTWCIGHLLETAPPDSYDERYKRWN  60
            MRLFLCEKPSQ+KDIA+VLGA ++G GC +G++  VTWCIGHL+E+APP++Y+E+YKRW+
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQYKRWS  60

Query  61   LADLPIIPDKWKMLVKPKTASQFKAVKRLLGEARELVIATDADREGEMIARELVEHCRYR  120
            L +LPIIP++W++  K+ TA+Q+K VK+L+G+A ELVIATDADREGEMIARE+++ C YR
Sbjct  61   LEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGYR  120

Query  121  GPVQRLWLSALDDASIRKALARLLPGHETFNLYHSALGRSRADWLIGMNMSRLFTLLGRQ  180
            GP+QRLWLSAL+DASIRKAL+ L P+ E++ LY +AL+RSRADWL+GMN+SRLFTLLGRQ
Sbjct  121  GPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGRQ  180

Query  181  SGYQGVLPVGRVQTPTLRLVVDRDRSIANFVPVPFWAIDVQLEHAGQRFNAQWRAPEDVC  240
            +GY+GVL+VGRVQTPTL LVV RDR IA FV+VPFW+I+V L  +G+ F A W A+++  
Sbjct  181  AGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGCS  240

Query  241  DDQGRCLKQDLAQRAATDIGHAGTARAVKVATERVREAAPLPFDLGTLQELCSKKFGLGA  300
            DD GRCL+Q  AQ+AA  +  AG+A+ V V+TERVREA+PLPFDLGTLQ++CS++++L+ 
Sbjct  241  DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALDV  300

Query  301  QETLDIAQALYETHKLITYPRSDCGYLPQSQHAEAPAILAALQRADASLAPLQPYLEPQR  360
            QETLDIAQALYETHK  TYPRSD GYLP+S  AE PA+LAA+  +D+SL PL   L+  +
Sbjct  301  QETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRTQ  360

Query  361  RSRAWNDAKVSAHHGIIPTAAASDPSRLPAKHKAVYTLIRARYLAQFLPNHEYDRTQADF  420
            RSRAWND+KVSAHHGIIPT  +++ + ++ K  AVY LIRA+YLAQFLP+ E+DRT A++
Sbjct  361  RSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQL  420

Query  421  DCAGHALRAVGKQIVEPGWRRALPEA-LTPAKGREAPPAQVLPALREGQDCNVNGLQLKD  479
             C+G++L+AVGKQ++ PGW++ L+ +    A G   P +QVLPALREG  C+VN ++LK 
Sbjct  421  LCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLSCQVNHVDLKA  480

Query  480  LWTQPPKPFTEGDLIKAMKNVAKLVDDPRLKQKLKETTGIGTEATRASIIQGLLDRGYLV  539
            L TQPPKP+T+GDLIKAMK VAKLV DPRLKQKLKETTGIGTEATRASII+GLL+RGYL+
Sbjct  481  LKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERGYLL  540

Query  540  KNGKALSATPAAFSLIDAVPRAIADPGTTAIWEQALDMVQSGEMTLEEFVARQSAWMGKL  599
            K+G+++ A+ AA  LIDAVP AI+DPGTTA+WEQALDM+++G+MTLE FVA+QS+W+ +L
Sbjct  541  KKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWITQL  600

Query  600  VERCSGMRMTI  610
            V++  +  ++I
Sbjct  601  VQQYRAATLAI  611

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  670 bits (2532),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 393/611 (65%), Positives = 515/611 (85%), Gaps = 1/611 (0%)

Query  1    MRLFLCEKPSQAKDIAKVLGANRKGDGCWQGTDICVTWCIGHLLETAPPDSYDERYKRWN  60
            MRLFLCEKPSQ+KDIA+VLGA ++G GC +G++  VTWCIGHL+E+APP++Y+E+YKRW+
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQYKRWS  60

Query  61   LADLPIIPDKWKMLVKPKTASQFKAVKRLLGEARELVIATDADREGEMIARELVEHCRYR  120
            L +LPIIP++W++  K+ TA+Q+K VK+L+G+A ELVIATDADREGEMIARE+++ C YR
Sbjct  61   LEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGYR  120

Query  121  GPVQRLWLSALDDASIRKALARLLPGHETFNLYHSALGRSRADWLIGMNMSRLFTLLGRQ  180
            GP+QRLWLSAL+DASIRKAL+ L P+ E++ LY +AL+RSRADWL+GMN+SRLFTLLGRQ
Sbjct  121  GPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGRQ  180

Query  181  SGYQGVLPVGRVQTPTLRLVVDRDRSIANFVPVPFWAIDVQLEHAGQRFNAQWRAPEDAC  240
            +GY+GVL+VGRVQTPTL LVV RDR IA FV+VPFW+I+V L  +G+ F A W A+++  
Sbjct  181  AGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGCS  240

Query  241  DDQGRCLKQSLAQQAAADIGHAGTARAVKVATERVREAAPLPFDLGTLQELCSKKFGLGA  300
            DD GRCL+Q+ AQQAA  +  AG+A+ V V+TERVREA+PLPFDLGTLQ++CS++++L+ 
Sbjct  241  DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALDV  300

Query  301  QETLDIAQALYETHKLITYPRSDCGYLPQSQHAEAPAILAALQRADASLAPLQPYLEPQR  360
            QETLDIAQALYETHK  TYPRSD GYLP+S  AE PA+LAA+  +D+SL PL   L+  +
Sbjct  301  QETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRTQ  360

Query  361  RSRAWNDAKVSAHHGIIPTAAASDPSRLPAKHKAVYTLIRARYLAQFLPNHEYDRTQADF  420
            RSRAWND+KVSAHHGIIPT  +++ + ++ K  AVY LIRA+YLAQFLP+ E+DRT A++
Sbjct  361  RSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQL  420

Query  421  DCAGHALRAVGKQIVEPGWRRALPEA-LTPAKGREAPPAQVLPALREGQDCNVHGLQLKD  479
             C+G++L+AVGKQ++ PGW++ L+ +    A G   P +QVLPALREG  C+V+ ++LK 
Sbjct  421  LCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLSCQVNHVDLKA  480

Query  480  LWTQPPKPFTEGDLIKAMKNVAKLVDDPRLKQKLKETTGIGTEATRASIIQGLLDRGYLV  539
            L TQPPKP+T+GDLIKAMK VAKLV DPRLKQKLKETTGIGTEATRASII+GLL+RGYL+
Sbjct  481  LKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERGYLL  540

Query  540  KNGKALSATPAAFSLIDAVPRAIADPGTTAIWEQALDMVQSGEMPLEEFVARQSAWMGKL  599
            K+G+++ A+ AA  LIDAVP AI+DPGTTA+WEQALDM+++G+M LE FVA+QS+W+ +L
Sbjct  541  KKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWITQL  600

Query  600  VERCSGMRMTI  610
            V++  +  ++I
Sbjct  601  VQQYRAATLAI  611

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  669 bits (2529),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 400/611 (66%), Positives = 516/611 (85%), Gaps = 1/611 (0%)

Query  1    MRLFLCEKPSQAKDIAKVLGAQRRGDGCWQGTDVCVTWCIGHLLETAPPDSYDERYKRWS  60
            MRLFLCEKPSQ+KDIA+VLGA +RG GC +G++  VTWCIGHL+E+APP++Y+E+YKRWS
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQYKRWS  60

Query  61   LDDLPIIPEKWKMTVKPKTASQYKAVKRLLGEARELVIATDADREGEMIARELVEHCRYR  120
            L++LPIIPE+W++  K+ TA+Q K VK+L+G+A ELVIATDADREGEMIARE+++ C YR
Sbjct  61   LEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGYR  120

Query  121  GPIQRLWLSALDDASIRKALARLLPGQETFNLYHSALGRSRADWLIGMNMSRLFTLLGRQ  180
            GPIQRLWLSAL+DASIRKAL+ L P+ E++ LY +AL+RSRADWL+GMN+SRLFTLLGRQ
Sbjct  121  GPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGRQ  180

Query  181  SGYQGVLPVGRVQTPTLRLVVDRDRSIADFVPVPFWAIDVQLESAGNVFNAQWRAPEDAC  240
            +GY+GVL+VGRVQTPTL LVV RDR IA FV+VPFW+I+V L ++G+ F A W A+++  
Sbjct  181  AGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGCS  240

Query  241  DDQGRCLKQALAQQAAHDMQAAGSARVMKIATERVRETAPLPFDLGTLQEVCSKKLGLGA  300
            DD GRCL+QA AQQAA+ ++ AGSA+V+ ++TERVRE++PLPFDLGTLQ+VCS++L+L+ 
Sbjct  241  DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALDV  300

Query  301  QETLDIAQALYETHKLITYPRSDSGYLPLSQHGEAPGILAALQRADASLAPLQPYLDPQR  360
            QETLDIAQALYETHK  TYPRSDSGYLP S  +E P++LAA+  +D+SL PL   LD  +
Sbjct  301  QETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRTQ  360

Query  361  RSRAWNDQKVSAHHGIIPTAAASDPSRLPPKYKAVYTLIRARYLAQFLPNHEYDRTQADF  420
            RSRAWND KVSAHHGIIPT  +++ + ++ K  AVY LIRA+YLAQFLP+ E+DRT A++
Sbjct  361  RSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQL  420

Query  421  DCAGHTLRAVGKQIIEPGWRRALPEALMPQ-KGREAPPAQVLPALREGQDCAVQGLQLKD  479
             C+G+TL+AVGKQ+I PGW++ L+ +   +  G   P +QVLPALREG  C V+ ++LK 
Sbjct  421  LCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLSCQVNHVDLKA  480

Query  480  LWTQPPKPFTEGDLIKAMKNVAKLVEDPLLKQKLKETTGIGTEATRASIIQGLLDRGYLV  539
            L TQPPKP+T+GDLIKAMK VAKLV DP LKQKLKETTGIGTEATRASII+GLL+RGYL+
Sbjct  481  LKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERGYLL  540

Query  540  KNGKALSATPAAFSLIDAVPRAIADPGTTAIWEQALDMVQNGEMSLDEFVARQSAWMGKL  599
            K+G+++ A+ AA  LIDAVP AI+DPGTTA+WEQALDM++ G+M+L+ FVA+QS+W+ +L
Sbjct  541  KKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWITQL  600

Query  600  VQRCSGMRLTI  610
            VQ+  +  L+I
Sbjct  601  VQQYRAATLAI  611

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  669 bits (2531),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 392/611 (65%), Positives = 515/611 (85%), Gaps = 1/611 (0%)

Query  1    MRLFLCEKPSQAKDIAKVLGANRKGDGCWQGTDICVTWCIGHLLETAPPDSYDERYKRWN  60
            MRLFLCEKPSQ+KDIA+VLGA ++G GC +G++  VTWCIGHL+E+APP++Y+E+YKRW+
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQYKRWS  60

Query  61   LADLPIIPDKWKMLVKPKTASQFKAVKRLLGEARELVIATDADREGEMIARELVEHCRYR  120
            L +LPIIP++W++  K+ TA+Q+K VK+L+G+A ELVIATDADREGEMIARE+++ C YR
Sbjct  61   LEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGYR  120

Query  121  GPVQRLWLSALDDASIRKALARLLPGHETFNLYHSALGRSRADWLIGMNMSRLFTLLGRQ  180
            GP+QRLWLSAL+DASIRKAL+ L P+ E++ LY +AL+RSRADWL+GMN+SRLFTLLGRQ
Sbjct  121  GPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGRQ  180

Query  181  SGYQGVLPVGRVQTPTLRLVVDRDRSIANFVPVPFWAIDVQLEHAGQRFNAQWRAPEDAC  240
            +GY+GVL+VGRVQTPTL LVV RDR IA FV+VPFW+I+V L  +G+ F A W A+++  
Sbjct  181  AGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGCS  240

Query  241  DDQGRCLKQSLAQQAATDIGHAGTARAVKVATERVREAAPLPFDLGTLQELCSKKFGLGA  300
            DD GRCL+Q+ AQQAA  +  AG+A+ V V+TERVREA+PLPFDLGTLQ++CS++++L+ 
Sbjct  241  DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALDV  300

Query  301  QETLDIAQALYETHKLITYPRSDCGYLPQSQHAEAPAILSALQRADASLAPLQPYLEPQR  360
            QETLDIAQALYETHK  TYPRSD GYLP+S  AE PA+L+A+  +D+SL PL   L+  +
Sbjct  301  QETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRTQ  360

Query  361  RSRAWNDAKVSAHHGIIPTAAASDPSRLPAKHKAVYTLIRARYLAQFLPNHEYDRTQADF  420
            RSRAWND+KVSAHHGIIPT  +++ + ++ K  AVY LIRA+YLAQFLP+ E+DRT A++
Sbjct  361  RSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQL  420

Query  421  DCAGHALRAVGKQIVEPGWRRALPEA-LTPAKGREAPPAQVLPALREGQDCNVHGLQLKD  479
             C+G++L+AVGKQ++ PGW++ L+ +    A G   P +QVLPALREG  C+V+ ++LK 
Sbjct  421  LCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLSCQVNHVDLKA  480

Query  480  LWTQPPKPFTEGDLIKAMKNVAKLVDDPRLKQKLKETTGIGTEATRASIIQGLLDRGYLV  539
            L TQPPKP+T+GDLIKAMK VAKLV DPRLKQKLKETTGIGTEATRASII+GLL+RGYL+
Sbjct  481  LKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERGYLL  540

Query  540  KNGKALSATPAAFSLIDAVPRAIADPGTTAIWEQALDMVQSGEMPLEEFVARQSAWMGKL  599
            K+G+++ A+ AA  LIDAVP AI+DPGTTA+WEQALDM+++G+M LE FVA+QS+W+ +L
Sbjct  541  KKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWITQL  600

Query  600  VERCSGMRMTI  610
            V++  +  ++I
Sbjct  601  VQQYRAATLAI  611

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  668 bits (2525),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 398/611 (66%), Positives = 515/611 (85%), Gaps = 1/611 (0%)

Query  1    MRLFLCEKPSQAKDIAKVLGANRKGDGCWQGTDVCVTWCIGHLLETAPPDSYDERYKRWN  60
            MRLFLCEKPSQ+KDIA+VLGA ++G GC +G++  VTWCIGHL+E+APP++Y+E+YKRW+
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQYKRWS  60

Query  61   LADLPIIPEKWKMLVKPKTASQFKAVKRLLGEARELVIATDADREGEMIARELVEHCRYR  120
            L +LPIIPE+W++  K+ TA+Q+K VK+L+G+A ELVIATDADREGEMIARE+++ C YR
Sbjct  61   LEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGYR  120

Query  121  GPVQRLWLSALDDASIRKALARLLPGHETFNLYHSALGRSRADWLIGMNMSRLFTLLGRQ  180
            GP+QRLWLSAL+DASIRKAL+ L P+ E++ LY +AL+RSRADWL+GMN+SRLFTLLGRQ
Sbjct  121  GPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGRQ  180

Query  181  SGYQGVLPVGRVQTPTLRLVVDRDRGIADFVPVPFWAIDVQLEHAGFGFNAQWRAPDDAC  240
            +GY+GVL+VGRVQTPTL LVV RDR IA FV+VPFW+I+V L  +G +F A W A+D+  
Sbjct  181  AGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGCS  240

Query  241  DDQGRCLNQALAQQAAVDIGNAGTARAVKVTTERVREAAPLPFDLGTLQELCSKKFGLGA  300
            DD GRCL+QA AQQAA  +  AG+A+ V VTTERVREA+PLPFDLGTLQ++CS++++L+ 
Sbjct  241  DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALDV  300

Query  301  QETLDIAQALYETHKLITYPRSDCGYLPQSQHAEAPAILAALQRSDASLAPLQPYLEPQR  360
            QETLDIAQALYETHK  TYPRSD GYLP+S  AE PA+LAA+  +D+SL PL   L+  +
Sbjct  301  QETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRTQ  360

Query  361  RSRAWNDAKVSAHHGIIPTAAASDPSRLPAKHKAVYTLIRARYLAQFLPNHEYDRTQADF  420
            RSRAWND+KVSAHHGIIPT  +++ + ++ K  AVY LIRA+YLAQFLP+ E+DRT A++
Sbjct  361  RSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQL  420

Query  421  DCAGHALRAVGKQIVEPGWRRALPEA-LTPAKGREAPPAQVLPALREGQDCTVQGLQLKD  479
             C+G++L+AVGKQ++ PGW++ L+ +    A G   P +QVLPALREG  C V+ ++LK 
Sbjct  421  LCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLSCQVNHVDLKA  480

Query  480  LWTQPPKPFTEGDLIKAMKNVAKLVDDPRLKQKLKETTGIGTEATRASIIQGLLDRGYLV  539
            L TQPPKP+T+GDLIKAMK VAKLV DPRLKQKLKETTGIGTEATRASII+GLL+RGYL+
Sbjct  481  LKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERGYLL  540

Query  540  KNGKALSATPAAFSLIDAVPRAIADPGTTAIWEQALDMVQSGEMTLEEFVARQSAWMGKL  599
            K+G+++ A+ AA  LIDAVP AI+DPGTTA+WEQALDM+++G+MTLE FVA+QS+W+ +L
Sbjct  541  KKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWITQL  600

Query  600  VERCSGMRMTI  610
            V++  +  ++I
Sbjct  601  VQQYRAATLAI  611

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  666 bits (2519),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 398/611 (66%), Positives = 515/611 (85%), Gaps = 1/611 (0%)

Query  1    MRLFLCEKPSQAKDIAKVLGANRKGDGCWQGTDVCVTWCIGHLLETAPPDSYDERYKRWN  60
            MRLFLCEKPSQ+KDIA+VLGA ++G GC +G++  VTWCIGHL+E+APP++Y+E+YKRW+
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQYKRWS  60

Query  61   LADLPIIPEKWKMLVKPKTASQFKAVKRLLGEARELVIATDADREGEMIARELVEHCRYR  120
            L +LPIIPE+W++  K+ TA+Q+K VK+L+G+A ELVIATDADREGEMIARE+++ C YR
Sbjct  61   LEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGYR  120

Query  121  GPVQRLWLSALDDASIRKALARLLPGHETFNLYHSALGRSRADWLIGMNMSRLFTLLGRQ  180
            GP+QRLWLSAL+DASIRKAL+ L P+ E++ LY +AL+RSRADWL+GMN+SRLFTLLGRQ
Sbjct  121  GPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGRQ  180

Query  181  SGYQGVLPVGRVQTPTLRLVVDRDRSIADFVPVPFWAIDVQLEHAGFGFNAQWRAPDDAC  240
            +GY+GVL+VGRVQTPTL LVV RDR IA FV+VPFW+I+V L  +G +F A W A+D+  
Sbjct  181  AGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGCS  240

Query  241  DDQGRCLNqalaqqaaaDIGNAGTARAVKVTTERVREAAPLPFDLGTLQELCSKKFGLGA  300
            DD GRCL+QA AQQAA  +  AG+A+ V VTTERVREA+PLPFDLGTLQ++CS++++L+ 
Sbjct  241  DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALDV  300

Query  301  QETLDIAQALYETHKLITYPRSDCGYLPQSQHAEAPAILAALQRSDASLAPLQPYLEPQR  360
            QETLDIAQALYETHK  TYPRSD GYLP+S  AE PA+LAA+  +D+SL PL   L+  +
Sbjct  301  QETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRTQ  360

Query  361  RSRAWNDAKVSAHHGIIPTAAASDPSRLPAKHKAVYTLIRARYLAQFLPNHEYDRTQADF  420
            RSRAWND+KVSAHHGIIPT  +++ + ++ K  AVY LIRA+YLAQFLP+ E+DRT A++
Sbjct  361  RSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQL  420

Query  421  DCAGHALRAVGKQIVEPGWRRALPEA-LTPAKGREAPPAQVLPALREGQDCTVQGLQLKD  479
             C+G++L+AVGKQ++ PGW++ L+ +    A G   P +QVLPALREG  C V+ ++LK 
Sbjct  421  LCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLSCQVNHVDLKA  480

Query  480  LWTQPPKPFTEGDLIKAMKNVAKLVDDPRLKQKLKETTGIGTEATRASIIQGLLDRGYLV  539
            L TQPPKP+T+GDLIKAMK VAKLV DPRLKQKLKETTGIGTEATRASII+GLL+RGYL+
Sbjct  481  LKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERGYLL  540

Query  540  KNGKALSATPAAFSLIDAVPRAIADPGTTAIWEQALDMVQSGEMTLEEFVARQSAWMGKL  599
            K+G+++ A+ AA  LIDAVP AI+DPGTTA+WEQALDM+++G+MTLE FVA+QS+W+ +L
Sbjct  541  KKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWITQL  600

Query  600  VERCSGMRMTI  610
            V++  +  ++I
Sbjct  601  VQQYRAATLAI  611

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  666 bits (2519),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 392/611 (65%), Positives = 515/611 (85%), Gaps = 1/611 (0%)

Query  4    MRLFLCEKPSQAKDIAKVLQATRRGDGCWLGPDLAVTWCIGHLLETAPPDAYDARYKRWD  63
            MRLFLCEKPSQ+KDIA+VL A +RG GC  G++  VTWCIGHL+E+APP+AY+ +YKRW 
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQYKRWS  60

Query  64   LSDLPIVPEHWKMLVKPKTASQYKVIKRLLGECRELIIATDADREGEMIARELVEHCRYR  123
            L +LPI+PE+W++  K+ TA+Q K++K+L+G+  EL+IATDADREGEMIARE+++ C YR
Sbjct  61   LEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGYR  120

Query  124  GPIRRLWLSALDDASIRKALAALKPGTETFSLYHSALGRSRADWLIGMNMSRLFTLLGRQ  183
            GPI+RLWLSAL+DASIRKAL+ALKP++E+++LY +AL+RSRADWL+GMN+SRLFTLLGRQ
Sbjct  121  GPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGRQ  180

Query  184  SGYQGVLSVGRVQTPTLRLVVDRDRSIADFVPVPWWAIEVQLLAEGTPFTAQWRAPEDAC  243
            +GY+GVLSVGRVQTPTL LVV RDR IA FV+VP W+IEV L + G +F A W A+++  
Sbjct  181  AGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGCS  240

Query  244  DDQGRCLKQELAQQAAQDMRHAGSARLVALKTERIREMPPLPFDLGTLQEICSKKLGLGA  303
            DD GRCL+Q  AQQAA+ +R AGSA++VA+ TER+RE PPLPFDLGTLQ++CS++L+L+ 
Sbjct  241  DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALDV  300

Query  304  QETLDIAQALYETHKVITYPRSDCGYLPQSQHGEAPAILAALERTDPALAGLMHHIDPRR  363
            QETLDIAQALYETHK  TYPRSD GYLP+S  +E PA+LAA+  TDP+L  L++++D  +
Sbjct  301  QETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRTQ  360

Query  364  RSRAWNDARVGAHHGIIPTAAAQSLDRLVGKQCAVYTLIRARYLAQFLPNHEYDRTQADF  423
            RSRAWND++V+AHHGIIPT  + +L  + +K  AVY LIRA+YLAQFLP+ E+DRT A++
Sbjct  361  RSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQL  420

Query  424  DCAGHALRAVGKRIVEPGWRRALPEA-LTPAKGRETPPSQELPALREGQDCAVAEVTLKD  482
             C+G++L+AVGK+++ PGW++ L+ +    A G   P SQ LPALREG  C V +V LK 
Sbjct  421  LCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLSCQVNHVDLKA  480

Query  483  LWTQPPKPYTEGDLIKAMKNVAKLVDDPRLKQKLKDTTGIGTEATRAGIIQALIERGYLL  542
            L TQPPKPYT+GDLIKAMK VAKLV DPRLKQKLK+TTGIGTEATRA+II++L+ERGYLL
Sbjct  481  LKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERGYLL  540

Query  543  KQGKALAATPAAFSLIDAVPRPIADPGTTAIWEQALDMVQSGEMSLEAFVAKQSAWMSKL  602
            K+G+++ A+ AA  LIDAVP +I+DPGTTA+WEQALDM+++G+M+LE+FVAKQS+W+++L
Sbjct  541  KKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWITQL  600

Query  603  IERCAGLRLTI  613
            +++  +  L+I
Sbjct  601  VQQYRAATLAI  611

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  666 bits (2519),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 392/611 (65%), Positives = 515/611 (85%), Gaps = 1/611 (0%)

Query  4    MRLFLCEKPSQAKDIAKVLQATRRGDGCWLGPDLAVTWCIGHLLETAPPDAYDARYKRWD  63
            MRLFLCEKPSQ+KDIA+VL A +RG GC  G++  VTWCIGHL+E+APP+AY+ +YKRW 
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQYKRWS  60

Query  64   LSDLPIVPEHWKMLVKPKTASQYKVIKRLLGECRELIIATDADREGEMIARELVEHCRYR  123
            L +LPI+PE+W++  K+ TA+Q K++K+L+G+  EL+IATDADREGEMIARE+++ C YR
Sbjct  61   LEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGYR  120

Query  124  GPIRRLWLSALDDASIRKALAALKPGTETFSLYHSALGRSRADWLIGMNMSRLFTLLGRQ  183
            GPI+RLWLSAL+DASIRKAL+ALKP++E+++LY +AL+RSRADWL+GMN+SRLFTLLGRQ
Sbjct  121  GPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGRQ  180

Query  184  SGYQGVLSVGRVQTPTLRLVVDRDRSIADFVPVPWWAIEVQLLAEGTPFTAQWRAPEDAC  243
            +GY+GVLSVGRVQTPTL LVV RDR IA FV+VP W+IEV L + G +F A W A+++  
Sbjct  181  AGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGCS  240

Query  244  DDQGRCLKQELAQQAAQDMRHAGSARLVALKTERIREMPPLPFDLGTLQEICSKKLGLGA  303
            DD GRCL+Q  AQQAA+ +R AGSA++VA+ TER+RE PPLPFDLGTLQ++CS++L+L+ 
Sbjct  241  DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALDV  300

Query  304  QETLDIAQALYETHKVITYPRSDCGYLPQSQHGEAPAILAALERTDPALAGLMHHIDPRR  363
            QETLDIAQALYETHK  TYPRSD GYLP+S  +E PA+LAA+  TDP+L  L++++D  +
Sbjct  301  QETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRTQ  360

Query  364  RSRAWNDARVGAHHGIIPTAAAQSLDRLVGKQCAVYTLIRARYLAQFLPNHEYDRTQADF  423
            RSRAWND++V+AHHGIIPT  + +L  + +K  AVY LIRA+YLAQFLP+ E+DRT A++
Sbjct  361  RSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQL  420

Query  424  DCAGHALRAVGKRIVEPGWRRALPEA-LTPAKGRETPPSQELPALREGQDCAVAEVTLKD  482
             C+G++L+AVGK+++ PGW++ L+ +    A G   P SQ LPALREG  C V +V LK 
Sbjct  421  LCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLSCQVNHVDLKA  480

Query  483  LWTQPPKPYTEGDLIKAMKNVAKLVDDPRLKQKLKDTTGIGTEATRAGIIQALIERGYLL  542
            L TQPPKPYT+GDLIKAMK VAKLV DPRLKQKLK+TTGIGTEATRA+II++L+ERGYLL
Sbjct  481  LKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERGYLL  540

Query  543  KQGKALAATPAAFSLIDAVPRPIADPGTTAIWEQALDMVQSGEMSLEAFVAKQSAWMSKL  602
            K+G+++ A+ AA  LIDAVP +I+DPGTTA+WEQALDM+++G+M+LE+FVAKQS+W+++L
Sbjct  541  KKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWITQL  600

Query  603  IERCAGLRLTI  613
            +++  +  L+I
Sbjct  601  VQQYRAATLAI  611

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  666 bits (2519),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 392/611 (65%), Positives = 515/611 (85%), Gaps = 1/611 (0%)

Query  4    MRLFLCEKPSQAKDIAKVLQATRRGDGCWLGPDLAVTWCIGHLLETAPPDAYDARYKRWD  63
            MRLFLCEKPSQ+KDIA+VL A +RG GC  G++  VTWCIGHL+E+APP+AY+ +YKRW 
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQYKRWS  60

Query  64   LSDLPIVPEHWKMLVKPKTASQYKVIKRLLGECRELIIATDADREGEMIARELVEHCRYR  123
            L +LPI+PE+W++  K+ TA+Q K++K+L+G+  EL+IATDADREGEMIARE+++ C YR
Sbjct  61   LEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGYR  120

Query  124  GPIRRLWLSALDDASIRKALAALKPGTETFSLYHSALGRSRADWLIGMNMSRLFTLLGRQ  183
            GPI+RLWLSAL+DASIRKAL+ALKP++E+++LY +AL+RSRADWL+GMN+SRLFTLLGRQ
Sbjct  121  GPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGRQ  180

Query  184  SGYQGVLSVGRVQTPTLRLVVDRDRSIADFVPVPWWAIEVQLLAEGTPFTAQWRAPEDAC  243
            +GY+GVLSVGRVQTPTL LVV RDR IA FV+VP W+IEV L + G +F A W A+++  
Sbjct  181  AGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGCS  240

Query  244  DDQGRCLKQELAQQAAQDMRHAGSARLVALKTERIREMPPLPFDLGTLQEICSKKLGLGA  303
            DD GRCL+Q  AQQAA+ +R AGSA++VA+ TER+RE PPLPFDLGTLQ++CS++L+L+ 
Sbjct  241  DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALDV  300

Query  304  QETLDIAQALYETHKVITYPRSDCGYLPQSQHGEAPAILAALERTDPALAGLMHHIDPRR  363
            QETLDIAQALYETHK  TYPRSD GYLP+S  +E PA+LAA+  TDP+L  L++++D  +
Sbjct  301  QETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRTQ  360

Query  364  RSRAWNDARVGAHHGIIPTAAAQSLDRLVGKQCAVYTLIRARYLAQFLPNHEYDRTQADF  423
            RSRAWND++V+AHHGIIPT  + +L  + +K  AVY LIRA+YLAQFLP+ E+DRT A++
Sbjct  361  RSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQL  420

Query  424  DCAGHALRAVGKRIVEPGWRRALPEA-LTPAKGRETPPSQELPALREGQDCAVAEVTLKD  482
             C+G++L+AVGK+++ PGW++ L+ +    A G   P SQ LPALREG  C V +V LK 
Sbjct  421  LCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLSCQVNHVDLKA  480

Query  483  LWTQPPKPYTEGDLIKAMKNVAKLVDDPRLKQKLKDTTGIGTEATRAGIIQALIERGYLL  542
            L TQPPKPYT+GDLIKAMK VAKLV DPRLKQKLK+TTGIGTEATRA+II++L+ERGYLL
Sbjct  481  LKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERGYLL  540

Query  543  KQGKALAATPAAFSLIDAVPRPIADPGTTAIWEQALDMVQSGEMSLEAFVAKQSAWMSKL  602
            K+G+++ A+ AA  LIDAVP +I+DPGTTA+WEQALDM+++G+M+LE+FVAKQS+W+++L
Sbjct  541  KKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWITQL  600

Query  603  IERCAGLRLTI  613
            +++  +  L+I
Sbjct  601  VQQYRAATLAI  611

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  665 bits (2513),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 390/611 (64%), Positives = 513/611 (84%), Gaps = 1/611 (0%)

Query  1    MRLFLCEKPSQAKDIAKVLGATRKGDGCWQGTDVCVTWCIGHLLETAPPDSYDERYKRWN  60
            MRLFLCEKPSQ+KDIA+VLGA ++G GC +G++  VTWCIGHL+E+APP++Y+E+YKRW+
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQYKRWS  60

Query  61   LADLPIIPDTWKMLVKPKTASQFKAVKRLLGEARELIIATDADREGEMIARELVEHCRYR  120
            L +LPIIP+ W++  K+ TA+Q+K VK+L+G+A EL+IATDADREGEMIARE+++ C YR
Sbjct  61   LEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGYR  120

Query  121  GPVQRLWLSALDDTSIRKALARLLPGHETFNLYHSALGRSRADWLIGMNMSRLFTLLGRQ  180
            GP+QRLWLSAL+D+SIRKAL+ L P+ E++ LY +AL+RSRADWL+GMN+SRLFTLLGRQ
Sbjct  121  GPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGRQ  180

Query  181  SGYQGVLPVGRVQTPTLRLVVDRDRSIADFVPVPFWAIDVQLEHAGQRFNAQWRAPEDAC  240
            +GY+GVL+VGRVQTPTL LVV RDR IA FV+VPFW+I+V L  +G+ F A W A+++  
Sbjct  181  AGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGCS  240

Query  241  DDQGRCLNQGLAQQAATAIGNAGTARAVKVTTERMREAAPLPFDLGTLQELCSKKFGLGA  300
            DD GRCL+Q+ AQQAA  +  AG+A+ V VTTER+REA+PLPFDLGTLQ++CS++++L+ 
Sbjct  241  DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALDV  300

Query  301  QETLDIAQALYETHKLITYPRSDCGYLPQSQHAEAPAILAALQRADASLAPLQPYLEPQR  360
            QETLDIAQALYETHK  TYPRSD GYLP+S  AE PA+LAA+  +D+SL PL   L+  +
Sbjct  301  QETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRTQ  360

Query  361  RSRAWNDAKVSAHHGIIPTAAASDPSRLPAKHKAVYTLIRARYLAQFLPNHEYDRTQADF  420
            RSRAWND+KVSAHHGIIPT  +++ + ++ K  AVY LIRA+YLAQFLP+ E+DRT A++
Sbjct  361  RSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQL  420

Query  421  DCAGHALRAVGKQIVEPGWRRALPEA-LTPAKGREAPPAQVLPVLREGQDCTVQGLQLKD  479
             C+G++L+AVGKQ++ PGW++ L+ +    A G   P +QVLP LREG  C V+ ++LK 
Sbjct  421  LCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLSCQVNHVDLKA  480

Query  480  LWTQPPKPFTEGDLIKAMKNVAKLVDDPRLKQKLKETTGIGTEATRASIIQGLLDRGYLV  539
            L TQPPKP+T+GDLIKAMK VAKLV DPRLKQKLKETTGIGTEATRASII+GLL+RGYL+
Sbjct  481  LKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERGYLL  540

Query  540  KNGKALAATPAAFSLIDAVPRAIADPGTTAIWEQALDMVQSGEMSLEEFVARQSAWMGKL  599
            K+G+++ A+ AA  LIDAVP AI+DPGTTA+WEQALDM+++G+M+LE FVA+QS+W+ +L
Sbjct  541  KKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWITQL  600

Query  600  VERCSGMRMTI  610
            V++  +  ++I
Sbjct  601  VQQYRAATLAI  611

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  663 bits (2508),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 393/611 (65%), Positives = 513/611 (84%), Gaps = 1/611 (0%)

Query  1    MRLFLCEKPSQAKDIAKVLGANRKGDGCWQGTDVCVTWCIGHLLETAPPDSYDERYKRWN  60
            MRLFLCEKPSQ+KDIA+VLGA ++G GC +G++  VTWCIGHL+E+APP++Y+E+YKRW+
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQYKRWS  60

Query  61   LADLPIIPDKWKMLVKPKTASQFKAVKRLLGEARELVIATDADREGEMIARELVEHCRYR  120
            L +LPIIP++W++  K+ TA+Q+K VK+L+G+A ELVIATDADREGEMIARE+++ C YR
Sbjct  61   LEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGYR  120

Query  121  GPVQRLWLSALDDASIRKALARLLPGHETFNLYHSALGRSRADWLIGMNMSRLFTLLGRQ  180
            GP+QRLWLSAL+DASIRKAL+ L P+ E++ LY +AL+RSRADWL+GMN+SRLFTLLGRQ
Sbjct  121  GPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGRQ  180

Query  181  SGYQGVLPVGRVQTPTLRLVVDRDRSIADFVPVPFWAIEVQLEHAAQRFNAQWRAPEDAC  240
            +GY+GVL+VGRVQTPTL LVV RDR IA FV+VPFW+IEV L  +++ F A W A+++  
Sbjct  181  AGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGCS  240

Query  241  DDQGRCLKQDLAQQAATDIGNAATARAVKVATERVREAAPLPFDLGTLQELCSKKFGLGA  300
            DD GRCL+Q  AQQAA  +  A++A+ V V+TERVREA+PLPFDLGTLQ++CS++++L+ 
Sbjct  241  DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALDV  300

Query  301  QETLDIAQALYETHKLITYPRSDCGYLPQSQHAEAPAILAALQRADASLTPLQPYLEPQR  360
            QETLDIAQALYETHK  TYPRSD GYLP+S  AE PA+LAA+  +D+SL PL   L+  +
Sbjct  301  QETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRTQ  360

Query  361  RSRAWNDAKVSAHHGIIPTAAASDPSRLPAKHKAVYTLIRARYLAQFLPNHEYDRTQADF  420
            RSRAWND+KVSAHHGIIPT  +++ + ++ K  AVY LIRA+YLAQFLP+ E+DRT A++
Sbjct  361  RSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQL  420

Query  421  DCAGHALRAVGKQIVEPGWRRALPEA-LTPAKGREAPPAQVLPALCEGQDCTVHGLQLKD  479
             C+G++L+AVGKQ++ PGW++ L+ +    A G   P +QVLPAL EG  C V+ ++LK 
Sbjct  421  LCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLSCQVNHVDLKA  480

Query  480  LWTQPPKPFTEGDLIKAMKNVAKLVDDPRLKQKLKETTGIGTEATRASIIQGLLDRGYLV  539
            L TQPPKP+T+GDLIKAMK VAKLV DPRLKQKLKETTGIGTEATRASII+GLL+RGYL+
Sbjct  481  LKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERGYLL  540

Query  540  KNGKALAATPAAFSLIDAVPRAIADPGTTAIWEQALDMVQSGEMTLEEFVARQSTWMGKL  599
            K+G+++ A+ AA  LIDAVP AI+DPGTTA+WEQALDM+++G+MTLE FVA+QSTW+ +L
Sbjct  541  KKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWITQL  600

Query  600  VERCSGMRMTI  610
            V++  +  ++I
Sbjct  601  VQQYRAATLAI  611

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  662 bits (2504),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 393/615 (64%), Positives = 515/615 (84%), Gaps = 1/615 (0%)

Query  1    MRLFLCEKPSQAKDIAKILGANRKGDGCWQGTDVCVTWCIGHLLETAPPDSYDERYKRWN  60
            MRLFLCEKPSQ+KDIA++LGA ++G GC +G++  VTWCIGHL+E+APP++Y+E+YKRW+
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQYKRWS  60

Query  61   LADLPIIPEKWKMLVKPKTASQFKAVKRLLGEARELVIATDADREGEMIARELVEHCRYR  120
            L +LPIIPE+W++  K+ TA+Q+K VK+L+G+A ELVIATDADREGEMIARE+++ C YR
Sbjct  61   LEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGYR  120

Query  121  GPIQRLWLSALDDASIRKALARLLPGQDTFNLYHSALGRSRADWLIGMNMSRLFTLLGRQ  180
            GPIQRLWLSAL+DASIRKAL+ L P+ +++ LY +AL+RSRADWL+GMN+SRLFTLLGRQ
Sbjct  121  GPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGRQ  180

Query  181  SGYQGVLPVGRVQTPTLRLVVDRDRSIADFVPVPFWAIEVQLEHAGLVFNAQWRAPEGIC  240
            +GY+GVL+VGRVQTPTL LVV RDR IA FV+VPFW+IEV L  +G  F A W A++G  
Sbjct  181  AGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGCS  240

Query  241  DDQGRCLNQALAQQAATDIGNARSARVLKVTTERVREAAPLPFDLGTLQELCSKKFGLGA  300
            DD GRCL+QA AQQAA  +  A SA+V+ VTTERVREA+PLPFDLGTLQ++CS++++L+ 
Sbjct  241  DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALDV  300

Query  301  QETLDIAQALYETHKLITYPRSDCGYLPVSQHSEAPAILTALQRVDSSLAPLQAHLEPQR  360
            QETLDIAQALYETHK  TYPRSD GYLP S  +E PA+L+A+   D+SL PL  +L+  +
Sbjct  301  QETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRTQ  360

Query  361  RSRAWNDAKVTAHHGIIPTAAASDPSRLPAKHKAVYTLIRARYLAQFLPNHEYDRTQAEF  420
            RSRAWND+KV+AHHGIIPT  +++ + ++ K  AVY LIRA+YLAQFLP+ E+DRT A++
Sbjct  361  RSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQL  420

Query  421  DCAGHALRAVGKQIVEPGWRRALPEALA-PAKGREAPPAQVLPTLCESQDCSVQGLQLKD  479
             C+G++L+AVGKQ++ PGW++ L+ + A  A G   P +QVLP+L E+  C V+ ++LK 
Sbjct  421  LCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLSCQVNHVDLKA  480

Query  480  LWTQPPKPFTEGDLIKAMKNVAKLVDDPRLKQKLKETTGIGTEATRASIIQGLLDRGYLV  539
            L TQPPKP+T+GDLIKAMK VAKLV DPRLKQKLKETTGIGTEATRASII+GLL+RGYL+
Sbjct  481  LKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERGYLL  540

Query  540  KNGKALAATPAAFSLIDAVPRAIADPGTTAIWEQALDMVQSGEMSLEDFVARQSAWMGKL  599
            K+G+++ A+ AA  LIDAVP AI+DPGTTA+WEQALDM+++G+M+LE FVA+QS+W+ +L
Sbjct  541  KKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWITQL  600

Query  600  VERCSGMRMTINGPA  614
            V++  +  ++I+ P 
Sbjct  601  VQQYRAATLAIKLPE  615

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  656 bits (2479),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 390/611 (64%), Positives = 511/611 (84%), Gaps = 1/611 (0%)

Query  1    MRLFLCEKPSQAKDIAKVLGANRRGDGCWLGPGVTVTWCIGHLLETAPPDAYDARYKRWV  60
            MRLFLCEKPSQ+KDIA+VLGA +RG GC  G+G  VTWCIGHL+E+APP+AY+ +YKRW 
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQYKRWS  60

Query  61   LGDLPIVPERWKMLVKPKTASQFKAVKRLLGEACELVIATDADREGEMIARELVEHCRYR  120
            L +LPI+PERW++  K+ TA+Q+K VK+L+G+A ELVIATDADREGEMIARE+++ C YR
Sbjct  61   LEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGYR  120

Query  121  GPIQRLWLSALDDASIRKALAALKPGAETFSLYHSALGRSRADWLMGMNMSRLFTLLGRQ  180
            GPIQRLWLSAL+DASIRKAL+ALKP++E+++LY +AL+RSRADWL+GMN+SRLFTLLGRQ
Sbjct  121  GPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGRQ  180

Query  181  SGYQGVLPVGRVQTPTLRLVVDRDRSIADFVPVPYWTIEVALQAGDIPFTAQWRAAEDRC  240
            +GY+GVL+VGRVQTPTL LVV RDR IA FV+VP+W+IEV+L +G+ +F A W AA++  
Sbjct  181  AGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGCS  240

Query  241  DDQGRCLDPEHarqaaaaigsatqaLVVKLRTERMREAPPLPFDLGTLQEICSKKLGLGA  300
            DD GRCL+   A+QAA  +  A  A VV + TER+REAPPLPFDLGTLQ++CS++L+L+ 
Sbjct  241  DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALDV  300

Query  301  QETLDIAQSLYEIHKLITYPRSDCGYLPLSQHGEAPAIIAALGRSDPSLSELLTLVQPQR  360
            QETLDIAQ+LYE HK  TYPRSD GYLP S  +E PA++AA+  +DPSL  LL  ++  +
Sbjct  301  QETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRTQ  360

Query  361  RSRAWNDGKVGAHHGIIPTAAATDLSRLAGKQRAVYTLVRARYLAQFLPNHEYDRTQADF  420
            RSRAWND+KV+AHHGIIPT  +++L+ +++K  AVY L+RA+YLAQFLP+ E+DRT A++
Sbjct  361  RSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQL  420

Query  421  DCAGQALRAVGKVIVEPGWRRALPEALTPAKGREPTP-AQALPPLSEGQHCNVMGVNLKD  479
             C+GQ+L+AVGK ++ PGW++ L+ + +   + E+ P +Q LP+L EG  C+V  V+LK 
Sbjct  421  LCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLSCQVNHVDLKA  480

Query  480  LWTQPPKPFTEGDLIKAMKNVARLVDDPRLKQKLKDTTGIGTEATRAGIIQGLLDRGYLS  539
            L TQPPKP+T+GDLIKAMK VA+LV DPRLKQKLK+TTGIGTEATRA+II+GLL+RGYL 
Sbjct  481  LKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERGYLL  540

Query  540  KQGKALSASPAAFSLIDAVPRAIADPGTTAIWEQALDMVQSGEMSLEEFVAKQSAWMSKQ  599
            K+G+++ AS AA  LIDAVP AI+DPGTTA+WEQALDM+++G+M+LE FVAKQS+W+++ 
Sbjct  541  KKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWITQL  600

Query  600  VERCRDLRLTI  610
            V++ R   L+I
Sbjct  601  VQQYRAATLAI  611

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  654 bits (2474),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 389/611 (64%), Positives = 513/611 (84%), Gaps = 1/611 (0%)

Query  1    MRLFLCEKPSQAKDIAKVLGATRKGDGCWQGTDVCVTWCIGHLLETAPPDSYDERYKRWN  60
            MRLFLCEKPSQ+KDIA+VLGA ++G GC +G++  VTWCIGHL+E+APP++Y+E+YKRW+
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQYKRWS  60

Query  61   LADLPIIPDKWKMLVKPKTASQFKAVKRLLGEARELVIATDADREGEMIARELVEHCRYR  120
            L +LPIIP++W++  K+ TA+Q+K VK+L+G+A ELVIATDADREGEMIARE+++ C YR
Sbjct  61   LEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGYR  120

Query  121  GPVQRLWLSALDDTSIRKALARLLPGHETFNLYHSALGRSRADWLIGMNMSRLFTLLGRQ  180
            GP+QRLWLSAL+D+SIRKAL+ L P+ E++ LY +AL+RSRADWL+GMN+SRLFTLLGRQ
Sbjct  121  GPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGRQ  180

Query  181  SGYQGVLPVGRVQTPTLRLVVDRDRSIADFVPVPFWAIDVQLEHAGQAFNAQWRAPEDAC  240
            +GY+GVL+VGRVQTPTL LVV RDR IA FV+VPFW+I+V L  +G++F A W A+++  
Sbjct  181  AGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGCS  240

Query  241  DDQGRCLNQSLaqqaaaaignagtaraVKVTTERVREAAPLLFDLGTLQELCSKKFGLGA  300
            DD GRCL+Q+ AQQAA  +  AG+A+ V VTTERVREA+PL FDLGTLQ++CS++++L+ 
Sbjct  241  DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALDV  300

Query  301  QETLDIAQALYETHKLITYPRSDCGYLPLSQHAEAPAILAALQRADAGLAPLQPHLEPQR  360
            QETLDIAQALYETHK  TYPRSD GYLP S  AE PA+LAA+  +D++L PL  +L+  +
Sbjct  301  QETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRTQ  360

Query  361  RSRVWNDAKVSAHHGIIPTAAASDPSRLPAKHKAVYTLIRARYLAQFLPNHEYDRTQADF  420
            RSR WND+KVSAHHGIIPT  +++ + ++ K  AVY LIRA+YLAQFLP+ E+DRT A++
Sbjct  361  RSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQL  420

Query  421  DCAGHALRAVGKQIVEPGWRRALPEA-LTPAKGREAPPAQVLPALSEGQDCTVQGLQLKD  479
             C+G++L+AVGKQ++ PGW++ L+ +    A G   P +QVLPAL EG  C V+ ++LK 
Sbjct  421  LCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLSCQVNHVDLKA  480

Query  480  LWTQPPKPFTEGDLIKAMKNVAKLVDDPRLKQKLKETTGIGTEATRASIIQGLLDRGYLV  539
            L TQPPKP+T+GDLIKAMK VAKLV DPRLKQKLKETTGIGTEATRASII+GLL+RGYL+
Sbjct  481  LKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERGYLL  540

Query  540  KNGKALAATPAAFSLIDAVPRAIADPGTTAIWEQALDMVQSGEMSLEEFVARQSAWMGKL  599
            K+G+++ A+ AA  LIDAVP AI+DPGTTA+WEQALDM+++G+M+LE FVA+QS+W+ +L
Sbjct  541  KKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWITQL  600

Query  600  VERCSGMRMTI  610
            V++  +  ++I
Sbjct  601  VQQYRAATLAI  611

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  652 bits (2466),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 386/614 (63%), Positives = 505/614 (83%), Gaps = 1/614 (0%)

Query  1    MRLFLCEKPSQAKDIASVLGATRRGDGCWLGNGVTVTWCIGHLLETAPPDAYDARYKRWV  60
            MRLFLCEKPSQ+KDIA VLGA +RG GC  G G  VTWCIGHL+E+APP+AY+ +YKRW 
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQYKRWS  60

Query  61   LDDLPIVPQQWKMRVKANTAAQFKAIKRLLGEASELVIATDADREGEMIARELLEHCRYR  120
            L++LPI+P++W++  KA TAAQ+K +K+L+G+ASELVIATDADREGEMIARE+++ C YR
Sbjct  61   LEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGYR  120

Query  121  GPIQRLWLSALDDASIRKALAALKPGASTYNLYQSALGRSRADWLIGMNMSRLFTLLGRK  180
            GPIQRLWLSAL+DASIRKAL+ALKP++ +  LY +AL+RSRADWL+GMN+SRLFTLLGR+
Sbjct  121  GPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGRQ  180

Query  181  SGYQGVLPVGRVQTPTLRLVVDRDRSIADFVPVPFWAIDVTLDGNGIPFTAVWRAPQDDC  240
            +GY+GVL+VGRVQTPTL LVV RDR IA FV+VPFW+I+V L   G +F A W A+++  
Sbjct  181  AGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGCS  240

Query  241  DEQGRCLKQEVAQRAAEAMQGAEHAVLEKLKTERMREAPPLLFDLGTLQQVCSKKLGLGA  300
            D+ GRCL+Q  AQ+AA+ ++ A  A +  + TER+REAPPL FDLGTLQ+VCS++L+L+ 
Sbjct  241  DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALDV  300

Query  301  QETLDIAQKLYETDKLITYPRSDCGYLPLSQHAEAPAILAALGQADPTLREVLAHTQTQR  360
            QETLDIAQ LYET+K  TYPRSD GYLP S  AE PA+LAA+  +DP+LR +L + +  +
Sbjct  301  QETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRTQ  360

Query  361  RSRAWNDAKVSAHHGIIPTLAAGGLTRLSGRPRAVYELIRARYLAQFLPNHEYDRTQADF  420
            RSRAWND+KVSAHHGIIPTL ++ L+ +S+++ AVY LIRA+YLAQFLP+ E+DRT A++
Sbjct  361  RSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQL  420

Query  421  DCAGHDLRAVGKQIVEPGWKRALPEA-LAPSKGREAPAPQALPALHEGQTCAVREVTLKD  479
             C+G+ L+AVGKQ++ PGW + L+ +    + G   P +Q LPAL+EG +C V +V LK 
Sbjct  421  LCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLSCQVNHVDLKA  480

Query  480  QFTQPPKPFTEGDLIQAMKNVARLVEDPLLKQKLKDTTGIGTEATRAGIIQGLLDRGYLT  539
              TQPPKP+T+GDLI+AMK VA+LV DP LKQKLK+TTGIGTEATRA+II+GLL+RGYL 
Sbjct  481  LKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERGYLL  540

Query  540  KQGKTLAATSAAFGLIDAVPRAIADPGTTAIWEQALDMVQSGEMPLDEFVAKQSAWMARQ  599
            K+G+T+ A+ AA  LIDAVP AI+DPGTTA+WEQALDM+++G+M L+ FVAKQS+W+++ 
Sbjct  541  KKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWITQL  600

Query  600  IERCRGLQLTISGP  613
            +++ R+  L+I  P
Sbjct  601  VQQYRAATLAIKLP  614

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  652 bits (2463),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 386/659 (59%), Positives = 526/659 (80%), Gaps = 5/659 (0%)

Query  1    MRLFICEKPSQARDIARVLQASRRGDGCLTGQNLTVTWCVGHLLETAPPETYGD-YKRWS  59
            MRLF+CEKPSQ++DIARVL A++RG GC  G    VTWC+GHL+E+APPE+YG+ YKRWS
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQYKRWS  60

Query  60   LDDLPIIPSRWQLVAKPKVAGQLKVISQLLRTCSEVVIATDADREGEMIAREILERCQYQ  119
            L++LPIIP RW++ +K+  A+QLK++ QL+   SE+VIATDADREGEMIAREI++ C Y+
Sbjct  61   LEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGYR  120

Query  120  GPILRLWLSALDETSIRRALSALRPGEQTLPLYHCALARSRADWLVGINLSRLFTLLGRR  179
            GPI RLWLSAL+++SIR+AL+AL+P+ ++LPLY  ALARSRADWLVG+NLSRLFTLLGR+
Sbjct  121  GPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGRQ  180

Query  180  AGFDGLLPVGRVQTPTLRLVVERDRAIASFVPLPFWTVDAHLEQDGIRFHARWQAPNAVS  239
            AG+DG+L+VGRVQTPTL LVV RDR IA FV++PFW+++  L  +G  F A W A+++ S
Sbjct  181  AGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGCS  240

Query  240  DAVGRCIDEtaaqqalrrltqaGSAQIDSVEVERVREGPPLPFDLGTLQEICSAKLGLGA  299
            D  GRC+++++AQQA  RL  AGSAQ+ +V  ERVRE+PPLPFDLGTLQ++CS +L+L+ 
Sbjct  241  DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALDV  300

Query  300  QETLATAQALYETHKVTTYPRSDCGYLPESMLDEVPRVLHALAAAAPSLGEILKEVDPSR  359
            QETL  AQALYETHK TTYPRSD GYLPESML EVP VL A+ ++ PSL  +L ++D ++
Sbjct  301  QETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRTQ  360

Query  360  RSRAWNSSKITAHHGIIPTAVTLDLAQLSERERAVYTLIRARYLAQFMPEHEYLKTQAQL  419
            RSRAWN SK++AHHGIIPT    +LA +S++  AVY LIRA+YLAQF+P+ E+ +T AQL
Sbjct  361  RSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQL  420

Query  420  HSQADHLVARGKQILARGWKAVINEADGNEPAEQA----QRLPTLRESATVALIDATLNA  475
               ++ L A GKQ++  GW  V+  ++++++  +A    Q LP+LRE+ +  + +  L+A
Sbjct  421  LCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLSCQVNHVDLKA  480

Query  476  QRTQPPKAYTEGTLVRAMKTIANQVADSRLKQKLKDSCGLGTEATRAAIIQGLIDHGYLT  535
             +TQPPK+YT+G L++AMK +A+ V+D+RLKQKLK++ G+GTEATRA+II+GL+++GYL 
Sbjct  481  LKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERGYLL  540

Query  536  KKKRSLaasaaaHTLIEAVPPEVADPVMTALWEQALDRIESGQLSVETFLAKQTEWLTRL  595
            KK R++ AS AA  LI+AVP+ ++DP  TA+WEQALD IE+G++++ETF+AKQ+ W+T+L
Sbjct  541  KKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWITQL  600

Query  596  VRSNATLTLRPPPSKGPFCPVCRSAMRQRKGRTGSFWSCIRYPECKGTKPVAKTKRAKN  654
            V+   + TL    + GP CP+C SA RQR G+TG+FWSC RYP+CKGT PV + ++A  
Sbjct  601  VQQYRAATLAIKLPEGPACPLCGSATRQRTGKTGPFWSCCRYPDCKGTLPVQNGRQASA  659

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  650 bits (2456),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 381/659 (58%), Positives = 528/659 (81%), Gaps = 6/659 (0%)

Query  1    MRLFICEKPSQARDIARVLQASHRADGCLKGQNVTITWCVGHLLETAPPETYGD-YKRWS  59
            MRLF+CEKPSQ++DIARVL A++R+ GC +G    +TWC+GHL+E+APPE+YG+ YKRWS
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQYKRWS  60

Query  60   LDDLPIIPSQWKLVAKPKVAGQLKVISQLLRTCSEVVIATDADREGEMIAREILERCQYQ  119
            L++LPIIP +W++ +K+  A+QLK++ QL+   SE+VIATDADREGEMIAREI++ C Y+
Sbjct  61   LEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGYR  120

Query  120  GPILRLWLSALDEASIRRALGALRPGEETLPLYHCALARSRADWLVGINLSRLFTLLGRR  179
            GPI RLWLSAL++ASIR+ALGAL+P+ E+LPLY  ALARSRADWLVG+NLSRLFTLLGR+
Sbjct  121  GPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGRQ  180

Query  180  SGFDGLLPVGRVQTPTLRLVVERDRAIASFVPLPFWTVDVHLEQDGIRFQARWQAPTAVS  239
            +G+DG+L+VGRVQTPTL LVV RDR IA FV++PFW+++V L  +G  F A W A+ + S
Sbjct  181  AGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGCS  240

Query  240  DAVGRCIDETaaqqaqrrfiqaGTAEIDNAEVEHVREGPPLPFDLGTLQEICSAKLGLGA  299
            D  GRC+++++AQQA  R+  AG+A++     E+VRE+PPLPFDLGTLQ++CS +L+L+ 
Sbjct  241  DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALDV  300

Query  300  QETLATAQALYETHKATTYPRTDCGYLPESMLDEVPRVLHA-LAAAPSLGAVLKEVDPSR  358
            QETL  AQALYETHKATTYPR+D GYLPESML EVP VL A L++ PSL ++L ++D ++
Sbjct  301  QETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRTQ  360

Query  359  RSRAWNSSKITAHHGIIPTAVTLDLAQLSERERAVYTLIRARYLAQFMPEHEYLKTQALL  418
            RSRAWN SK++AHHGIIPT    +LA +S++  AVY LIRA+YLAQF+P+ E+ +T A L
Sbjct  361  RSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQL  420

Query  419  HSQADQLVARGKQILVRGWKAVINEADGNEPAEQA----QRLPTLRESATVALIDATLNA  474
               ++ L A GKQ+++ GW  V+  ++++++  +A    Q LP+LRE+ +  + +  L+A
Sbjct  421  LCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLSCQVNHVDLKA  480

Query  475  QRTQPPKAYTEGTLVKAMKTIANQVADPRLKQKLKDSCGLGTEATRAAIIQGLIDHGYLT  534
             +TQPPK+YT+G L+KAMK +A+ V+DPRLKQKLK++ G+GTEATRA+II+GL+++GYL 
Sbjct  481  LKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERGYLL  540

Query  535  KKKRSLaasaaaHTLIEAVPPEVADPVMTALWEQALDRIESGQLSVDTFLAKQAEWLTRL  594
            KK R++ AS AA  LI+AVP+ ++DP  TA+WEQALD IE+G+++++TF+AKQ+ W+T+L
Sbjct  541  KKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWITQL  600

Query  595  VRSNATLTLRPPPSKGPFCPVCRSTMRQRKGRTGSFWSCIRYPECKGTKPVAKAKRAKN  653
            V+   + TL    + GP CP+C S+ RQR G+TG+FWSC RYP+CKGT PV ++++A  
Sbjct  601  VQQYRAATLAIKLPEGPACPLCGSATRQRTGKTGPFWSCCRYPDCKGTLPVQNGRQASA  659

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  650 bits (2456),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 381/659 (58%), Positives = 528/659 (81%), Gaps = 6/659 (0%)

Query  1    MRLFICEKPSQARDIARVLQASHRADGCLKGQNVTITWCVGHLLETAPPETYGD-YKRWS  59
            MRLF+CEKPSQ++DIARVL A++R+ GC +G    +TWC+GHL+E+APPE+YG+ YKRWS
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQYKRWS  60

Query  60   LDDLPIIPSQWKLVAKPKVAGQLKVISQLLRTCSEVVIATDADREGEMIAREILERCQYQ  119
            L++LPIIP +W++ +K+  A+QLK++ QL+   SE+VIATDADREGEMIAREI++ C Y+
Sbjct  61   LEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGYR  120

Query  120  GPILRLWLSALDEASIRRALGALRPGEETLPLYHCALARSRADWLVGINLSRLFTLLGRR  179
            GPI RLWLSAL++ASIR+ALGAL+P+ E+LPLY  ALARSRADWLVG+NLSRLFTLLGR+
Sbjct  121  GPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGRQ  180

Query  180  SGFDGLLPVGRVQTPTLRLVVERDRAIASFVPLPFWTVDVHLEQDGIRFQARWQAPTAVS  239
            +G+DG+L+VGRVQTPTL LVV RDR IA FV++PFW+++V L  +G  F A W A+ + S
Sbjct  181  AGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGCS  240

Query  240  DAVGRCIDETaaqqaqrrfiqaGTAEIDNAEVEHVREGPPLPFDLGTLQEICSAKLGLGA  299
            D  GRC+++++AQQA  R+  AG+A++     E+VRE+PPLPFDLGTLQ++CS +L+L+ 
Sbjct  241  DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALDV  300

Query  300  QETLATAQALYETHKATTYPRTDCGYLPESMLDEVPRVLHA-LAAAPSLGAVLKEVDPSR  358
            QETL  AQALYETHKATTYPR+D GYLPESML EVP VL A L++ PSL ++L ++D ++
Sbjct  301  QETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRTQ  360

Query  359  RSRAWNSSKITAHHGIIPTAVTLDLAQLSERERAVYTLIRARYLAQFMPEHEYLKTQALL  418
            RSRAWN SK++AHHGIIPT    +LA +S++  AVY LIRA+YLAQF+P+ E+ +T A L
Sbjct  361  RSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQL  420

Query  419  HSQADQLVARGKQILVRGWKAVINEADGNEPAEQA----QRLPTLRESATVALIDATLNA  474
               ++ L A GKQ+++ GW  V+  ++++++  +A    Q LP+LRE+ +  + +  L+A
Sbjct  421  LCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLSCQVNHVDLKA  480

Query  475  QRTQPPKAYTEGTLVKAMKTIANQVADPRLKQKLKDSCGLGTEATRAAIIQGLIDHGYLT  534
             +TQPPK+YT+G L+KAMK +A+ V+DPRLKQKLK++ G+GTEATRA+II+GL+++GYL 
Sbjct  481  LKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERGYLL  540

Query  535  KKKRSLaasaaaHTLIEAVPPEVADPVMTALWEQALDRIESGQLSVDTFLAKQAEWLTRL  594
            KK R++ AS AA  LI+AVP+ ++DP  TA+WEQALD IE+G+++++TF+AKQ+ W+T+L
Sbjct  541  KKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWITQL  600

Query  595  VRSNATLTLRPPPSKGPFCPVCRSTMRQRKGRTGSFWSCIRYPECKGTKPVAKAKRAKN  653
            V+   + TL    + GP CP+C S+ RQR G+TG+FWSC RYP+CKGT PV ++++A  
Sbjct  601  VQQYRAATLAIKLPEGPACPLCGSATRQRTGKTGPFWSCCRYPDCKGTLPVQNGRQASA  659

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  648 bits (2451),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 393/611 (65%), Positives = 506/611 (83%), Gaps = 1/611 (0%)

Query  1    MRLYLCEKPSQAKDIAAVLGARRRGDGCWLGTDVTVTWCIGHLLETAPPDAYDARYKRWV  60
            MRL+LCEKPSQ+KDIA VLGA +RG GC  G++  VTWCIGHL+E+APP+AY+ +YKRW 
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQYKRWS  60

Query  61   LADLPIIPEKWKMTVKPRTASQYKAVKRLLGEAAELVIATDADREGEMIARELVEHCRYR  120
            L +LPIIPE+W++  K+ TA+Q K VK+L+G+A+ELVIATDADREGEMIARE+++ C YR
Sbjct  61   LEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGYR  120

Query  121  GPIRRLWLSALDDASIRKALAALKPGNETFSLYHSALGRSRADWLIGMNMSRLFTLLGRQ  180
            GPI+RLWLSAL+DASIRKAL+ALKP++E+++LY +AL+RSRADWL+GMN+SRLFTLLGRQ
Sbjct  121  GPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGRQ  180

Query  181  SGYQGVLPVGRVQTPTLRLVVDRDRSIADFVPVPYWAIDVQLLHNGTAFTAQWRAASEVC  240
            +GY+GVL+VGRVQTPTL LVV RDR IA FV+VP+W+I+V L   G +F A W AA    
Sbjct  181  AGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGCS  240

Query  241  DDQDRCLNqalaqqaadamrgaasaRVIKLRTERMREVAPLPFDLGTLQEVCSKKLGLGA  300
            DD +RCL+QA AQQAAD +R A+SA+V+ + TER+RE +PLPFDLGTLQ+VCS++L+L+ 
Sbjct  241  DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALDV  300

Query  301  QETLDIAQALYETYKVITYPRSDCGYLPLSQHNEAPAILAALRQADPALNTLHDHLDPQR  360
            QETLDIAQALYET K  TYPRSD GYLP S   E PA+LAA+  +DP+L  L ++LD  +
Sbjct  301  QETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRTQ  360

Query  361  RSRAWNDAKVSAHHGIIPTAAAKNLDKLAGKQRAVYTLIRARYLAQFLPNHEYDRTQADF  420
            RSRAWND+KVSAHHGIIPT  + NL  +++K  AVY LIRA+YLAQFLP+ E+DRT A++
Sbjct  361  RSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQL  420

Query  421  DCAGQALRAVGKQIIEQGWKRALPEALA-ATKGREAPAPQTLPNLAEGIDCAVAGVQLKD  479
             C+GQ+L+AVGKQ+I  GW + L+ + A  + G   P +Q LP L EG+ C V  V+LK 
Sbjct  421  LCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLSCQVNHVDLKA  480

Query  480  LWTQPPKPFTEGDLIKAMKNVAKLVEDPLLKQKLKDTTGIGTEATRASIIQGLLDRGYLV  539
            L TQPPKP+T+GDLIKAMK VAKLV DP LKQKLK+TTGIGTEATRASII+GLL+RGYL+
Sbjct  481  LKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERGYLL  540

Query  540  KNGKALAATPAAFSLIDAVPRAIADPGTTAIWEQALDMVQSGEMSLEEFVTKQAAWMSKQ  599
            K+G+++ A+ AA  LIDAVP AI+DPGTTA+WEQALDM+++G+M+LE FV+KQ++W+++ 
Sbjct  541  KKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWITQL  600

Query  600  VSRCAGLSLTI  610
            V +  + +L+I
Sbjct  601  VQQYRAATLAI  611

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  648 bits (2450),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 390/614 (64%), Positives = 517/614 (85%), Gaps = 0/614 (0%)

Query  1    MQLYLCEKPSQARDIAKVLGANRRGDGCLQGAGVTVTWCIGHLLETAPPDAYDPRYKRWV  60
            M+L+LCEKPSQ++DIA+VLGA +RG GC +GAG  VTWCIGHL+E+APP+AY+ +YKRW 
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQYKRWS  60

Query  61   LADLPIVPERWKMLVKPKTASQFKAVKRLLGECSELVIATDADREGEMIARELVEHCRYR  120
            L +LPI+PERW++  K+ TA+Q+K VK+L+G+ SELVIATDADREGEMIARE+++ C YR
Sbjct  61   LEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGYR  120

Query  121  GPIRRLWLSALDDASIRKALAALKPGAETFNLYHAALGRSRADWLIGMNMSRLFTLLGRQ  180
            GPI+RLWLSAL+DASIRKAL+ALKP++E++ LY AAL+RSRADWL+GMN+SRLFTLLGRQ
Sbjct  121  GPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGRQ  180

Query  181  SGYQGVLPVGRVQTPTLRLVVDRDRSIADFIPVPFWAIDVQLLADGTAFTAQWQAPDDHC  240
            +GY+GVL+VGRVQTPTL LVV RDR IA F++VPFW+I+V L ++G +F A W A+D+  
Sbjct  181  AGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGCS  240

Query  241  DDQGRCLDqaraqqaadamrnaasarLVKLKTERQREAAPLPFDLGTLQEVCSKKLGLGA  300
            DD GRCL+QA AQQAAD +R A+SA++V + TER REA+PLPFDLGTLQ+VCS++L+L+ 
Sbjct  241  DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALDV  300

Query  301  QETLDIAQALYETHKLITYPRSDCGYLPLSQHGEARAIVAALTQADPTLAALQPHLDLSR  360
            QETLDIAQALYETHK  TYPRSD GYLP S  +E  A++AA+  +DP+L +L  +LD ++
Sbjct  301  QETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRTQ  360

Query  361  RSRAWNDAKVSAHHGIIPTAAARGLERLSGRPRAVYELIRARYLAQFLPNHEYDRTQADF  420
            RSRAWND+KVSAHHGIIPT  +  L  +S+++ AVY LIRA+YLAQFLP+ E+DRT A++
Sbjct  361  RSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQL  420

Query  421  DCAGQALRAVGKRIVEPGWKRAMPEALAPTRGSREAPAPQSLPALQQGQDYAVGEVNLKD  480
             C+GQ+L+AVGK+++ PGW + ++ + A   ++   P +Q LPAL++G    V +V+LK 
Sbjct  421  LCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLSCQVNHVDLKA  480

Query  481  QQTQPPKPFTEGDLIKAMKNVAKLVDDPRLKQKLKDTTGIGTEATRAGIIQGLLDRGYLV  540
             +TQPPKP+T+GDLIKAMK VAKLV DPRLKQKLK+TTGIGTEATRA+II+GLL+RGYL+
Sbjct  481  LKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERGYLL  540

Query  541  RQGKALAATPAAFSLIDAVPRPIADPGTTAIWEQALDMVQSGEMPLEEFVAKQSAWMSKL  600
            ++G+++ A+ AA  LIDAVP +I+DPGTTA+WEQALDM+++G+M LE FVAKQS+W+++L
Sbjct  541  KKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWITQL  600

Query  601  VERCAGLRMTISGP  614
            V++  +  ++I  P
Sbjct  601  VQQYRAATLAIKLP  614

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  647 bits (2445),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 384/614 (63%), Positives = 514/614 (84%), Gaps = 0/614 (0%)

Query  1    MQLYLCEKPSQARDIAKVLGANRRGDGCLQGAGVTVTWCIGHLLETAPPDAYDPRYKRWV  60
            M+L+LCEKPSQ++DIA+VLGA +RG GC +GAG  VTWCIGHL+E+APP+AY+ +YKRW 
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQYKRWS  60

Query  61   LADLPIVPERWKMLVKPKTASQFKAVKRLLGECSELVIATDADREGEMIARELVEHCRYR  120
            L +LPI+PERW++  K+ TA+Q+K VK+L+G+ SELVIATDADREGEMIARE+++ C YR
Sbjct  61   LEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGYR  120

Query  121  GPIRRLWLSALDDASIRKALAALKPGAETFNLYHAALGRSRADWLIGMNMSRLFTLLGRQ  180
            GPI+RLWLSAL+DASIRKAL+ALKP++E++ LY AAL+RSRADWL+GMN+SRLFTLLGRQ
Sbjct  121  GPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGRQ  180

Query  181  SGYQGVLPVGRVQTPTLRLVVDRDRSIADFIPVPFWAIDVQLLADGTAFTAQWQAPDDYC  240
            +GY+GVL+VGRVQTPTL LVV RDR IA F++VPFW+I+V L ++G +F A W A+D+  
Sbjct  181  AGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGCS  240

Query  241  DDQGRCLDqaraqqaaeamrnaacarLLKLKTERQREAAPLPFDLGTLQEVCSKKLGLGA  300
            DD GRCL+QA AQQAA+ +R A+ A+++ + TER REA+PLPFDLGTLQ+VCS++L+L+ 
Sbjct  241  DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALDV  300

Query  301  QETLDIAQALYETHKLITYPRSDCGYLPLSQHGEARAIVAALAQSDPTLAALEPHLDLSR  360
            QETLDIAQALYETHK  TYPRSD GYLP S  +E  A++AA+  +DP+L +L  +LD ++
Sbjct  301  QETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRTQ  360

Query  361  RSRAWNDAKVGAHHGIIPTAAVRGLERLSGRPRAVYELIRARYLAQFLPNHEYDRTQADF  420
            RSRAWND+KV+AHHGIIPT     L  +S+++ AVY LIRA+YLAQFLP+ E+DRT A++
Sbjct  361  RSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQL  420

Query  421  DCAGQALRAVGKRIVEPGWKRAMPEALAPARGNREAPAPQSLPTLQQGQDYAVGEINLKD  480
             C+GQ+L+AVGK+++ PGW + ++ + A   +    P +Q LP+L++G    V +++LK 
Sbjct  421  LCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLSCQVNHVDLKA  480

Query  481  QQTHPPKPFTEGDLIKAMKNVAKLVDDPRLKQKLKDTTGIGTEATRAGIIQGLLDRGYLL  540
             +T+PPKP+T+GDLIKAMK VAKLV DPRLKQKLK+TTGIGTEATRA+II+GLL+RGYLL
Sbjct  481  LKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERGYLL  540

Query  541  RQGKALAATPAAFSLIDAVPRPIADPGTTAIWEQALDMVQSGEMPLEEFVAKQSAWMSKL  600
            ++G+++ A+ AA  LIDAVP +I+DPGTTA+WEQALDM+++G+M LE FVAKQS+W+++L
Sbjct  541  KKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWITQL  600

Query  601  VERCAGLRMTISGP  614
            V++  +  ++I  P
Sbjct  601  VQQYRAATLAIKLP  614

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  646 bits (2442),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 389/611 (64%), Positives = 509/611 (84%), Gaps = 1/611 (0%)

Query  1    MRLYLCEKPSQAKDIAAVLGAKRRGDGCWLGTDVTVTWCIGHLLETAPPDAYDAKYKRWV  60
            MRL+LCEKPSQ+KDIA VLGA +RG GC  G++  VTWCIGHL+E+APP+AY+ +YKRW 
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQYKRWS  60

Query  61   LADLPIIPDKWKMTVKPRTASQYKAVKRLLGEASELIIATDADREGEMIARELVEHCRYR  120
            L +LPIIP++W++  K+ TA+Q K VK+L+G+ASEL+IATDADREGEMIARE+++ C YR
Sbjct  61   LEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGYR  120

Query  121  GPIRRLWLSALDEASIRKALAALKPGAETFSLYHSALGRSRADWLIGMNMSRLFTLLGRQ  180
            GPI+RLWLSAL++ASIRKAL+ALKP++E+++LY +AL+RSRADWL+GMN+SRLFTLLGRQ
Sbjct  121  GPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGRQ  180

Query  181  SGYQGVLPVGRVQTPTLRLVVDRDRSIADFVPVAYWAIDVQLLHGDTPFNAQWRAPNDAC  240
            +GY+GVL+VGRVQTPTL LVV RDR IA FV+V++W+I+V L  G+ +F A W A+++  
Sbjct  181  AGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGCS  240

Query  241  DDQDRCLNqalaqqaaaaissaasaRVVKLRTERMREVAPLPFDLGTLQEVCSKKLGLGA  300
            DD +RCL+QA AQQAA  +  A+SA+VV + TER+RE +PLPFDLGTLQ+VCS++L+L+ 
Sbjct  241  DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALDV  300

Query  301  QETLDIAQALYETYKVITYPRSDCGYLPLSQHNEAPGILAALRQADPSLEALREHLEPQR  360
            QETLDIAQALYET K  TYPRSD GYLP S   E P++LAA+  +DPSL +L E+L+  +
Sbjct  301  QETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRTQ  360

Query  361  RSRAWNDAKVSAHHGIIPTAAAKNLERLTGKHRAVYTLIRARYLAQFLPNHEYDRTQADF  420
            RSRAWND+KVSAHHGIIPT  + NL  +++K  AVY LIRA+YLAQFLP+ E+DRT A++
Sbjct  361  RSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQL  420

Query  421  DCAGEALRAVGKQIIEPGWKRALPEALA-PAKGREAPAPQTLPTLTQGAECAVADVKLKD  479
             C+G++L+AVGKQ+I PGW + L+ + A  A G   P +Q LP+L +G  C V +V LK 
Sbjct  421  LCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLSCQVNHVDLKA  480

Query  480  LWTQPPKPYTEGDLIKAMKNVAKLVEDPLLKQKLKDTTGIGTEATRASIIQGLLDRGYLV  539
            L TQPPKPYT+GDLIKAMK VAKLV DP LKQKLK+TTGIGTEATRASII+GLL+RGYL+
Sbjct  481  LKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERGYLL  540

Query  540  KNGKALSATPAAFSLIDAVPRAIADPGTTAIWEQALDMVQSGEMSLEEFVTKQAAWMSKQ  599
            K+G+++ A+ AA  LIDAVP AI+DPGTTA+WEQALDM+++G+M+LE FV+KQ++W+++ 
Sbjct  541  KKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWITQL  600

Query  600  VTRCAGLSLTI  610
            V +  + +L+I
Sbjct  601  VQQYRAATLAI  611

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  645 bits (2439),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 384/635 (61%), Positives = 517/635 (82%), Gaps = 3/635 (0%)

Query  1    MRLYLCEKPSQAKDIAAVLGASRRGDGCWLGNGITVTWCIGHLLETAPPDAYDAKYKRWV  60
            MRL+LCEKPSQ+KDIA VLGA++RG GC  G G  VTWCIGHL+E+APP+AY+ +YKRW 
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQYKRWS  60

Query  61   LADLPIVPEKWKMLVKPKTASQFKVVKRLLGEAQELVIATDADREGEMIARELVEHCRYR  120
            L +LPI+PE+W++  K+ TA+Q+K+VK+L+G+A ELVIATDADREGEMIARE+++ C YR
Sbjct  61   LEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGYR  120

Query  121  GPIQRLWLSALDDASIRKALAALKPGAETFSLYHSALGRSRADWLIGMNMSRLFTLLGRQ  180
            GPIQRLWLSAL+DASIRKAL+ALKP++E+++LY +AL+RSRADWL+GMN+SRLFTLLGRQ
Sbjct  121  GPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGRQ  180

Query  181  SGYQGVLPVGRVQTPTLRLVVDRDRSIADFVPVAYWAIDVDLHHERMTFTAQWRAAEEAC  240
            +GY+GVL+VGRVQTPTL LVV RDR IA FV+V++W+I+V+L     +F A W AA+   
Sbjct  181  AGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGCS  240

Query  241  DDQGRCLNPQLardaadamanaatarLVKLRTERMREVAPLPFDLGTLQEICSKKLGLGA  300
            DD GRCL+   A++AAD +  A++A++V + TER+RE +PLPFDLGTLQ++CS++L+L+ 
Sbjct  241  DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALDV  300

Query  301  QETLDIAQSLYETHKVITYPRSDCGYLPVSQHSEAPKILAALGRADAAVNALMPHIDPQR  360
            QETLDIAQ+LYETHK  TYPRSD GYLP S  +E P +LAA+  +D+++ +L+ ++D  +
Sbjct  301  QETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRTQ  360

Query  361  RSRAWNDAKVSAHHGIIPTGAGKEVGQLTGKHRAVYTLIRARYLAQFLPNHEYDRTQADF  420
            RSRAWND+KVSAHHGIIPT    +++ +++K  AVY LIRA+YLAQFLP+ E+DRT A++
Sbjct  361  RSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQL  420

Query  421  DCAGQALRAVGKVVIEPGWKRALPEA-LTPAKGREAPVPQALPTLVQGQDYAVAKVNLKD  479
             C+GQ+L+AVGK VI PGW + L+ +    A G   P +Q LP+L +G    V  V+LK 
Sbjct  421  LCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLSCQVNHVDLKA  480

Query  480  LWTQPPKPFTEGDLIKAMKNVAKLVEDPLLKQKLKDTTGIGTEATRAGIIQGLLDRGYLV  539
            L TQPPKP+T+GDLIKAMK VAKLV DP LKQKLK+TTGIGTEATRA+II+GLL+RGYL+
Sbjct  481  LKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERGYLL  540

Query  540  KNGKALSATPAAFSLIDAVPRAIADPGTTAIWEQALDMVQSGEMSLEEFVAKQAAWMSKQ  599
            K+G+++ A+ AA  LIDAVP AI+DPGTTA+WEQALDM+++G+M+LE FVAKQ++W+++ 
Sbjct  541  KKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWITQL  600

Query  600  VARCNGMRMTITGPASPAGR--GATPWKNKRKSAP  632
            V +  +  ++I  P +PA    G++ ++   K++P
Sbjct  601  VQQYRAATLAIKLPEGPACPLCGSATRQRTGKTGP  635

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  641 bits (2424),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 382/659 (58%), Positives = 526/659 (80%), Gaps = 5/659 (0%)

Query  1    MRLFICEKPSQARDIARVLQASRRADGYLKGPNLIVTWCVGHLLETAPPEAYGD-YKRWS  59
            MRLF+CEKPSQ++DIARVL A++R+ G  +G+  +VTWC+GHL+E+APPEAYG+ YKRWS
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQYKRWS  60

Query  60   LDDLPIIPSRWQLVAKPKVASQLKVINQLLRTCSEVVIATDADREGEMIAREILERCQYQ  119
            L++LPIIP RW++ +K+  A+QLK+++QL+   SE+VIATDADREGEMIAREI++ C Y+
Sbjct  61   LEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGYR  120

Query  120  GPILRLWLSALDEASIRRALGALRPGEQTLPLYHCALARSRADWLVGINLSRLFTLLGRR  179
            GPI RLWLSAL++ASIR+ALGAL+P+ ++LPLY  ALARSRADWLVG+NLSRLFTLLGR+
Sbjct  121  GPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGRQ  180

Query  180  AGFDGLLPVGRVQTPTLRLVVERDRAIASFVPQPFWTLDAHLEQDGIRFHARWQPTAAAS  239
            AG+DG+L+VGRVQTPTL LVV RDR IA FV+ PFW+++  L  +G  F A W ++ + S
Sbjct  181  AGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGCS  240

Query  240  DAVGRCIDEtaaqqalrrltqaGSAQIYSFEVERVREGPPLPFDLGMLQEICSAKLGLGA  299
            D  GRC+++++AQQA  RL  AGSAQ+ +   ERVRE+PPLPFDLG LQ++CS +L+L+ 
Sbjct  241  DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALDV  300

Query  300  QEALATAQALYENHKATTYPRTDCGYLPESMLDEAPRVLHalaaaaPSLGGILKEVDPSR  359
            QE+L  AQALYE HKATTYPR+D GYLPESML E P VL A+ ++ PSL  +L ++D ++
Sbjct  301  QETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRTQ  360

Query  360  RSRAWNSSKITAHHGIIPTAVTLDLAQLSERERAVYTLIRARYLAQFMPEHEYLKTQALL  419
            RSRAWN SK++AHHGIIPT    +LA +S++  AVY LIRA+YLAQF+P+ E+ +T A L
Sbjct  361  RSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQL  420

Query  420  QSQADQLIARGKQILVRGWKAVVNEADGNEPAEQA----QRLPTLRESATVALIDATLNA  475
               ++ L A GKQ+++ GW  V+  ++++++  +A    Q LP+LRE+ +  + +  L+A
Sbjct  421  LCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLSCQVNHVDLKA  480

Query  476  QSTQPPKAYTEGTLVKAMKTIANLVADPRLKQKLKDSCGLGTEATRAAIIQGLIDHGYLI  535
              TQPPK+YT+G L+KAMK +A+LV+DPRLKQKLK++ G+GTEATRA+II+GL+++GYL+
Sbjct  481  LKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERGYLL  540

Query  536  KKKRSLaasaaaHTLIEAVPPEVADPVMTALWEQALDRIESGQLSVETFLAKQAEWLTRL  595
            KK R++ AS AA  LI+AVP+ ++DP  TA+WEQALD IE+G++++ETF+AKQ+ W+T+L
Sbjct  541  KKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWITQL  600

Query  596  VRSNATLTLRPPPSKGPFCPVCCSSMRQRKGRTGSFWSCTRYPECKGTKPVAKAKRAKN  654
            V+   + TL    + GP CP+C S+ RQR G+TG+FWSC RYP+CKGT PV ++++A  
Sbjct  601  VQQYRAATLAIKLPEGPACPLCGSATRQRTGKTGPFWSCCRYPDCKGTLPVQNGRQASA  659

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  640 bits (2419),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 380/618 (62%), Positives = 507/618 (83%), Gaps = 1/618 (0%)

Query  1    MRLYLCEKPSQAKDIAAVLGASRRGDGCWLGNGVTVTWCIGHLLETAPPDAYDAKYKRWV  60
            MRL+LCEKPSQ+KDIA VLGA++RG GC  G G  VTWCIGHL+E+APP+AY+ +YKRW 
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQYKRWS  60

Query  61   LADLPIVPEKWKMLVKPKTASQYKAVKRLLGEAQELVIATDADREGEMIARELVEHCRYR  120
            L +LPI+PE+W++  K+ TA+Q K VK+L+G+A ELVIATDADREGEMIARE+++ C YR
Sbjct  61   LEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGYR  120

Query  121  GPIQRLWLSALDDASIRKALAALKPGAETFSLYHSALGRSRADWLIGMNMSRLFTLLGRQ  180
            GPIQRLWLSAL+DASIRKAL+ALKP++E+++LY +AL+RSRADWL+GMN+SRLFTLLGRQ
Sbjct  121  GPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGRQ  180

Query  181  SGYQGVLPVGRVQTPTLRLVVDRDRSIADFVPVAYWAIDVDLRHEHMTFTAQWRAPDDAC  240
            +GY+GVL+VGRVQTPTL LVV RDR IA FV+V++W+I+V+L     +F A W A+D+  
Sbjct  181  AGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGCS  240

Query  241  DDQDRCLNPQlardaadamlnaatarlVKLRTERMREVAPLPFDLGTLQEICSKKLGLGA  300
            DD +RCL+   A++AAD +  A++A++V + TER+RE +PLPFDLGTLQ++CS++L+L+ 
Sbjct  241  DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALDV  300

Query  301  QETLDIAQSLYETHKAITYPRSDCGYLPLSQHSEAPKILAALGRADTAVNELMSHIDPRR  360
            QETLDIAQ+LYETHKA TYPRSD GYLP S  +E P +LAA+  +D ++  L+ ++D  +
Sbjct  301  QETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRTQ  360

Query  361  RSRAWNDAKVSAHHGIIPTGAGKEVSQLTGKHRAVYTLIRARYLAQFLPNHEYDRTQADL  420
            RSRAWND+KVSAHHGIIPT    +++ +++K  AVY LIRA+YLAQFLP+ E+DRT A+L
Sbjct  361  RSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQL  420

Query  421  DCAGHALRAVGKVIIEPGWKRALPEALA-PAKGREAPAPQALPTLVQGHDYAVAKVNLKD  479
             C+G++L+AVGK +I PGW + L+ + A  A G   P +Q LP+L +G    V  V+LK 
Sbjct  421  LCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLSCQVNHVDLKA  480

Query  480  LWTQPPKPFTEGDLIKAMKNVAKLVEDPLLKQKLKDTTGIGTEATRAGIIQGLLDRGYLV  539
            L TQPPKP+T+GDLIKAMK VAKLV DP LKQKLK+TTGIGTEATRA+II+GLL+RGYL+
Sbjct  481  LKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERGYLL  540

Query  540  KNGKALSATPAAFSLIDAVPRAIADPGTTAIWEQALDMVQSGEMSLEEFIAKQAAWMSKQ  599
            K+G+++ A+ AA  LIDAVP AI+DPGTTA+WEQALDM+++G+M+LE F+AKQ++W+++ 
Sbjct  541  KKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWITQL  600

Query  600  VARCNGMRMTITGPASPA  617
            V +  +  ++I  P +PA
Sbjct  601  VQQYRAATLAIKLPEGPA  618

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  634 bits (2395),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 377/657 (58%), Positives = 524/657 (80%), Gaps = 5/657 (0%)

Query  1    MRLFICEKPSQARDIARVLQASWRGDGYLQGQNVTVTWCIGHLLETAPPESYGD-YKRWS  59
            MRLF+CEKPSQ++DIARVL A+ RG G  +G    VTWCIGHL+E+APPE+YG+ YKRWS
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQYKRWS  60

Query  60   LDDLPIIPDHWQLVVKPKVASQLKVIDQLLQRCAEVVIATDADREGEMIAREILERCQYQ  119
            L++LPIIP++W++  K+  A+QLK++ QL+ + +E+VIATDADREGEMIAREI++ C Y+
Sbjct  61   LEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGYR  120

Query  120  GPVLRLWLSALDEASIRRALAALRPGEQTLPLYHCALARSRADWLVGINLSRLFTLLGRR  179
            GP+ RLWLSAL++ASIR+AL+AL+P+ ++LPLY  ALARSRADWLVG+NLSRLFTLLGR+
Sbjct  121  GPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGRQ  180

Query  180  AGFDGVLPVGRVQTPTLRLVVERDRAIASFVPHPFWNVDAQLVADGVSFKASWQPPASVC  239
            AG+DGVL+VGRVQTPTL LVV RDR IA FV+ PFW+++  L ++G SF A+W ++ +  
Sbjct  181  AGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGCS  240

Query  240  DDEGRCLDEaaarqaalrlsqHGTARIGTIEVEHVREGPPLPFDLGTLQEVCSAKLGLGA  299
            DD GRCL++A+A+QAA RL   G+A++ ++  E+VRE+PPLPFDLGTLQ+VCS +L+L+ 
Sbjct  241  DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALDV  300

Query  300  QETLGIAQALYETHKATTYPRTDCGYLPESMLDEVPRILHALVAPSPALGQVIKALDPCR  359
            QETL+IAQALYETHKATTYPR+D GYLPESML EVP +L A+++  P+L  ++  LD  +
Sbjct  301  QETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRTQ  360

Query  360  RSRAWNSSKITAHHGIIPTAIKLDLTQLSEREQAVYALIRARYLAQFLPEHEYLKTQVLL  419
            RSRAWN SK++AHHGIIPT    +L+ +S++  AVY LIRA+YLAQFLP+ E+ +T   L
Sbjct  361  RSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQL  420

Query  420  HSQADQLLARGKQILVRGWKAVINETHGNEPGEQ----TQRLPTLRESVSVALTDAAAII  475
               ++ L A GKQ+++ GW  V+   ++++++ +    +Q LP+LRE++S  + +     
Sbjct  421  LCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLSCQVNHVDLKA  480

Query  476  QRTHPPKAYTEGTLVKAMKTIANQVADLRLKQTLRESCGLGTEATRAAIIQGLIDHGYLT  535
             +T+PPK+YT+G L+KAMK +A+ V+D RLKQ L+E+ G+GTEATRA+II+GL+++GYL 
Sbjct  481  LKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERGYLL  540

Query  536  KKKRSLaasaaaHTLIEAVPAEVADPVLTALWEQALGRIESGQLSVETFLAKQSQWLTRL  595
            KK R++ AS AA  LI+AVPA ++DP  TA+WEQAL+ IE+G++++ETF+AKQS W+T+L
Sbjct  541  KKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWITQL  600

Query  596  VRSNASLTLQPPPSKGPLCPVCCSGMRQRKGRTGSFWSCIRYPDCKGTKPVTKAKRP  652
            V+   + TL    + GP CP+C S+ RQR G+TG+FWSC RYPDCKGT PV +++++
Sbjct  601  VQQYRAATLAIKLPEGPACPLCGSATRQRTGKTGPFWSCCRYPDCKGTLPVQNGRQA  657

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  633 bits (2393),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 390/635 (62%), Positives = 523/635 (83%), Gaps = 2/635 (0%)

Query  1    MQLYLCEKPSQARDIAKVLGANRRGDGCLQGAGVTVTWCIGHLLETAPPDAYDPRYKRWV  60
            M+L+LCEKPSQ++DIA+VLGA +RG GC +GAG  VTWCIGHL+E+APP+AY+ +YKRW 
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQYKRWS  60

Query  61   LADLPIVPERWKMLVKPKTASQFKAVKRLLGECSELVIATDADREGEMIARELVEHCRYR  120
            L +LPI+PERW++  K+ TA+Q+K VK+L+G+ SELVIATDADREGEMIARE+++ C YR
Sbjct  61   LEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGYR  120

Query  121  GPIRRLWLSALDDASIRKALAALKPGAETFNLYHAALGRSRADWLIGMNMSRLFTLLGRQ  180
            GPI+RLWLSAL+DASIRKAL+ALKP++E++ LY AAL+RSRADWL+GMN+SRLFTLLGRQ
Sbjct  121  GPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGRQ  180

Query  181  SGYRGVLPVGRVQTPTLRLVVDRDRSIADFIPVPFWAIDVQLLADGAAFTAQWQAPDDLC  240
            +GY GVL+VGRVQTPTL LVV RDR IA F++VPFW+I+V L ++G +F A W A+D+  
Sbjct  181  AGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGCS  240

Query  241  DDQGRCLDqaraqqaadamrnaasarLLKLKTERQREAAPLPFDLGTLQEVCSKKLGLGA  300
            DD GRCL+QA AQQAAD +R A+SA+++ + TER REA+PLPFDLGTLQ+VCS++L+L+ 
Sbjct  241  DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALDV  300

Query  301  QETLDIAQALYETHKLITYPRSDCGYLPLSQHGEARAIVAALTQADPTLAALQPHLDLSR  360
            QETLDIAQALYETHK  TYPRSD GYLP S  +E  A++AA+  +DP+L +L  +LD ++
Sbjct  301  QETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRTQ  360

Query  361  RSRAWNDAKVGAHHGIIPTaaarglerlagrpraVYELIRARYLAQFLPNHEYDRTQADF  420
            RSRAWND+KV+AHHGIIPT  +  L  +++++ AVY LIRA+YLAQFLP+ E+DRT A++
Sbjct  361  RSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQL  420

Query  421  DCAGQALRAVGKRVVEPGWKRAMPEALAPARGNREEHAPQSLPALQQGGDYAVGEITLKD  480
             C+GQ+L+AVGK+V+ PGW + ++ + A   +      +Q LPAL++G    V ++ LK 
Sbjct  421  LCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLSCQVNHVDLKA  480

Query  481  QQTQPPKPFTEGDLIKAMKNVAKLVDDPRLKQKLKDTTGIGTEATRAGIIQGLLDRGYLV  540
             +TQPPKP+T+GDLIKAMK VAKLV DPRLKQKLK+TTGIGTEATRA+II+GLL+RGYL+
Sbjct  481  LKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERGYLL  540

Query  541  RQGKALAATPAAFSLIDAVPRPIADPGTTAIWEQALDMVQSGEMPLEEFVAKQSAWMSKL  600
            ++G+++ A+ AA  LIDAVP +I+DPGTTA+WEQALDM+++G+M LE FVAKQS+W+++L
Sbjct  541  KKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWITQL  600

Query  601  VE--RCAGLRMTISGPPVAAGRGGKPWKKKRSASP  633
            V+  R A L + ++  P  +  G+  +++   ++P
Sbjct  601  VQQYRAATLAIKLPEGPACPLCGSATRQRTGKTGP  635

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  632 bits (2388),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 387/618 (63%), Positives = 509/618 (83%), Gaps = 1/618 (0%)

Query  1    MQLYLCEKPSQAKDIAAVLGATRRGDGCWLGPGITVTWCIGHLLETAPPDAYDARYKRWV  60
            M+L+LCEKPSQ+KDIA VLGA +RG GC  G+G  VTWCIGHL+E+APP+AY+ +YKRW 
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQYKRWS  60

Query  61   LADLPIVPAQWKMTVKPKTASQYKAVKRLLGEAKELVIATDADREGEMIARELVEHCRYR  120
            L +LPI+P +W++  K+ TA+Q K VK+L+G+A ELVIATDADREGEMIARE+++ C YR
Sbjct  61   LEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGYR  120

Query  121  GPIRRLWLSALDEASIRKALAALKPGAETFNLYHSALGRSRADWLIGMNMSRLFTLLGRQ  180
            GPI+RLWLSAL++ASIRKAL+ALKP++E++ LY +AL+RSRADWL+GMN+SRLFTLLGRQ
Sbjct  121  GPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGRQ  180

Query  181  SGYQGVLPVGRVQTPTLRLVVDRDRSIADFVPVAYWAIDVQLSHEGTAFTAQWRADPDAC  240
            +GY+GVL+VGRVQTPTL LVV RDR IA FV+V++W+I+V LS  G +F A W A  +  
Sbjct  181  AGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGCS  240

Query  241  DDQERClnqalardaaqamanattarTLKVRTERLREAAPLPFDLGTLQEVCSKKLGLGA  300
            DD  RCL+QA A++AA+ +  A +A+ + V TER+REA+PLPFDLGTLQ+VCS++L+L+ 
Sbjct  241  DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALDV  300

Query  301  QETLDIAQSLYETYKLITYPRSDCGFLPLSQHSEapailaalaqaDPSLAPLREHLQPQR  360
            QETLDIAQ+LYET K  TYPRSD G+LP S  +E PA+LAA+  +DPSL PL E+L+  +
Sbjct  301  QETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRTQ  360

Query  361  KSRAWNDAKVSAHHGIIPTAAARNLDKLAGKQRAVYTLIRARYLAQFLPNHEYDRTQADF  420
            +SRAWND+KVSAHHGIIPT  + NL  +++K  AVY LIRA+YLAQFLP+ E+DRT A++
Sbjct  361  RSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQL  420

Query  421  DCAGQALRAVGKQIVEPGWKRALPEALA-PARGREAPTPQTLPALSEGRDCAVDEVKPKD  479
             C+GQ+L+AVGKQ++ PGW + L+ + A  A G   P +Q LPAL EG  C V++V  K 
Sbjct  421  LCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLSCQVNHVDLKA  480

Query  480  LWTQPPKPFTEGDLIKAMKNVAKLVEDPLLKQKLKDTTGIGTEATRASIIQGLLDRGYLV  539
            L TQPPKP+T+GDLIKAMK VAKLV DP LKQKLK+TTGIGTEATRASII+GLL+RGYL+
Sbjct  481  LKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERGYLL  540

Query  540  KNGKALSATPAAFSLIDAVPRAIADPGTTAIWEQALDMVQSGEMSLEEFVTRQAAWMSKH  599
            K+G+++ A+ AA  LIDAVP AI+DPGTTA+WEQALDM+++G+M+LE FV++Q++W+++ 
Sbjct  541  KKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWITQL  600

Query  600  VARCQGMSLTISGPASPA  617
            V + ++ +L+I  P +PA
Sbjct  601  VQQYRAATLAIKLPEGPA  618

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  630 bits (2380),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 387/618 (63%), Positives = 509/618 (83%), Gaps = 1/618 (0%)

Query  1    MQLYLCEKPSQAKDIAAVLGATRRGDGCWLGPGITVTWCIGHLLETAPPDAYDARYKRWV  60
            M+L+LCEKPSQ+KDIA VLGA +RG GC  G+G  VTWCIGHL+E+APP+AY+ +YKRW 
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQYKRWS  60

Query  61   LADLPIVPAQWKMTVKPKTASQYKAVKRLLGEAKELVIATDADREGEMIARELVEHCRYR  120
            L +LPI+P +W++  K+ TA+Q K VK+L+G+A ELVIATDADREGEMIARE+++ C YR
Sbjct  61   LEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGYR  120

Query  121  GPIRRLWLSALDEASIRKALAALKPGAETFNLYHSALGRSRADWLIGMNMSRLFTLLGRQ  180
            GPI+RLWLSAL++ASIRKAL+ALKP++E++ LY +AL+RSRADWL+GMN+SRLFTLLGRQ
Sbjct  121  GPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGRQ  180

Query  181  SGYQGVLPVGRVQTPTLRLVVDRDRSIADFVPIAYWAIDVQLSHEGTAFTAQWRADPDAC  240
            +GY+GVL+VGRVQTPTL LVV RDR IA FV++++W+I+V LS  G +F A W A  +  
Sbjct  181  AGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGCS  240

Query  241  DDQERClnqalardaamamsnaasarTLKVRTERLREAAPLPFDLGTLQEVCSKKLGLGA  300
            DD  RCL+QA A++AA  +  A+SA+ + V TER+REA+PLPFDLGTLQ+VCS++L+L+ 
Sbjct  241  DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALDV  300

Query  301  QETLDIAQSLYETYKLITYPRSDCGFLPLSQHSEapailaalaqaDPSLAPLREHLQPQR  360
            QETLDIAQ+LYET K  TYPRSD G+LP S  +E PA+LAA+  +DPSL PL E+L+  +
Sbjct  301  QETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRTQ  360

Query  361  KSRAWNDAKVSAHHGIIPTAAARNLDKLAGKQRAVYTLIRARYLAQFLPNHEYDRTQADF  420
            +SRAWND+KVSAHHGIIPT  + NL  +++K  AVY LIRA+YLAQFLP+ E+DRT A++
Sbjct  361  RSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQL  420

Query  421  DCAGQALRAVGKQIVEPGWKRALPEALA-PARGREAPAPQTLPALAEGRDCAVDEVKPKD  479
             C+GQ+L+AVGKQ++ PGW + L+ + A  A G   P +Q LPAL EG  C V++V  K 
Sbjct  421  LCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLSCQVNHVDLKA  480

Query  480  LWTQPPKPFTEGDLIKAMKNVAKLVEDPLLKQKLKDTTGIGTEATRASIIQGLLDRGYLV  539
            L TQPPKP+T+GDLIKAMK VAKLV DP LKQKLK+TTGIGTEATRASII+GLL+RGYL+
Sbjct  481  LKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERGYLL  540

Query  540  KNGKALSATPAAFSLIDAVPRAIADPGTTAIWEQALDMVQSGEMSLEEFVTRQAAWMSKH  599
            K+G+++ A+ AA  LIDAVP AI+DPGTTA+WEQALDM+++G+M+LE FV++Q++W+++ 
Sbjct  541  KKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWITQL  600

Query  600  VARCQGMSLTISGPASPA  617
            V + ++ +L+I  P +PA
Sbjct  601  VQQYRAATLAIKLPEGPA  618

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  628 bits (2374),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 382/618 (62%), Positives = 512/618 (83%), Gaps = 1/618 (0%)

Query  1    MRLFLCEKPSQAKDIAAALGATRRGDGCWVGANATVTWCIGHLLETAPPDAYDARYKRWV  60
            MRLFLCEKPSQ+KDIA  LGA +RG GC  GA + VTWCIGHL+E+APP+AY+ +YKRW 
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQYKRWS  60

Query  61   LEDLPIVPEKWKMLVKPRTASQFKAVKRLLGEATELVIATDADREGEMIARELIEHCRYR  120
            LE+LPI+PE+W++  K+ TA+Q+K VK+L+G+A+ELVIATDADREGEMIARE+I+ C YR
Sbjct  61   LEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGYR  120

Query  121  GPIQRLWLSALDDASIRKALAALKPGADTFSLYHSALGRSRADWLIGMNMSRLFTLLGRQ  180
            GPIQRLWLSAL+DASIRKAL+ALKP++++++LY +AL+RSRADWL+GMN+SRLFTLLGRQ
Sbjct  121  GPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGRQ  180

Query  181  SGYQGVLPVGRVQTPTLRLVVDRDRSIANFVPAPYWAIDVRLLHDNQAFIAQWRAPSDAC  240
            +GY+GVL+VGRVQTPTL LVV RDR IA FV+ P+W+I+V L  + ++F+A W A+ +  
Sbjct  181  AGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGCS  240

Query  241  DDQDRCLNqalaqqaaqamraaasaRLVKLRTERIREAAPLPFDLGTLQEICSKKLGLGA  300
            DD +RCL+QA AQQAA+ +R A+SA++V + TER+REA+PLPFDLGTLQ++CS++L+L+ 
Sbjct  241  DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALDV  300

Query  301  QETLDIAQSLYETHKVITYPRSDCGYLPNSQHGEAAGIIAALCKADPALANLSPHLDPQR  360
            QETLDIAQ+LYETHK  TYPRSD GYLP+S  +E ++++AA+  +DP+L  L  +LD  +
Sbjct  301  QETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRTQ  360

Query  361  RSRAWNDSKVTAHHGIIPTAAVRGVERLSGKPRAVYTLIRARYLAQFLPNHEYDRTQADF  420
            RSRAWNDSKV+AHHGIIPT     +  +S+K+ AVY LIRA+YLAQFLP+ E+DRT A++
Sbjct  361  RSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQL  420

Query  421  DCAGHALRAVGKQIVEPGWKRAMPEALAPAKGREapapqplpalF-QGCECAVAEVILKD  479
             C+G++L+AVGKQ++ PGW + ++ + A   + EA +   + + + +G  C V +V LK 
Sbjct  421  LCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLSCQVNHVDLKA  480

Query  480  LWTQPPKPFTEGDLIKAMKNVAKLVEDPLLKQKLKDTTGIGTEATRAGIIQGLLDRGYLT  539
            L TQPPKP+T+GDLIKAMK VAKLV DP LKQKLK+TTGIGTEATRA+II+GLL+RGYL 
Sbjct  481  LKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERGYLL  540

Query  540  KQGKSLCAAPAAFSLIDAVPRAIADPGTTAIWEQALDMVQSGEMSLEEFVAKQAAWMSKQ  599
            K+G+++ A+ AA  LIDAVP AI+DPGTTA+WEQALDM+++G+M+LE FVAKQ++W+++ 
Sbjct  541  KKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWITQL  600

Query  600  VSRCVGMRMSISGPASPA  617
            V +  +  ++I  P +PA
Sbjct  601  VQQYRAATLAIKLPEGPA  618

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  627 bits (2368),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 379/611 (63%), Positives = 508/611 (84%), Gaps = 1/611 (0%)

Query  1    MRLFLCEKPSQAKDIAAALGATRRGDGCWVGASATVTWCIGHLLETAPPDAYDARYKRWV  60
            MRLFLCEKPSQ+KDIA  LGA +RG GC  GA++ VTWCIGHL+E+APP+AY+ +YKRW 
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQYKRWS  60

Query  61   LEDLPIVPEKWKMLVKPRTASQFKAVKRLLGEANELVIATDADREGEMIARELVEHCRYR  120
            LE+LPI+PE+W++  K+ TA+Q+K VK+L+G+A+ELVIATDADREGEMIARE+++ C YR
Sbjct  61   LEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGYR  120

Query  121  GPIQRLWLSALDDASIRKALAALKPGADTFSLYHSALGRSRADWLIGMNMSRLFTLLGRQ  180
            GPIQRLWLSAL+DASIRKAL+ALKP++++++LY +AL+RSRADWL+GMN+SRLFTLLGRQ
Sbjct  121  GPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGRQ  180

Query  181  SGYQGVLPVGRVQTPTLRLVVDRDRSIADFVPAPFWAIDVKLLHENQAFIAQWRAPSDAC  240
            +GY+GVL+VGRVQTPTL LVV RDR IA FV+ PFW+I+V L    ++F+A W A+ +  
Sbjct  181  AGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGCS  240

Query  241  DDQDRCLNQPLaqqaadamrhaasarLVKLRTERMREAAPLPFDLGTLQEICSKKLGLGA  300
            DD +RCL+Q+ AQQAAD +R A+SA++V + TER+REA+PLPFDLGTLQ++CS++L+L+ 
Sbjct  241  DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALDV  300

Query  301  QETLDIAQSLYETHKVITYPRSDCGYLPNSQHGEAAGIITALGKTDPALAGLLPHLDPQR  360
            QETLDIAQ+LYETHK  TYPRSD GYLP+S  +E +++++A+  TDP+L  LL +LD  +
Sbjct  301  QETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRTQ  360

Query  361  RSRAWNDAKVTAHHGIIPTAAVRGVERLIGKPRAVYTLIRARYLAQFLPNHEYDRTQADF  420
            RSRAWND+KV+AHHGIIPT     +  + +K+ AVY LIRA+YLAQFLP+ E+DRT A++
Sbjct  361  RSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQL  420

Query  421  DCAGQALRAVGKQIVEPGWKRAMPEALAPAKGREapapqplpalF-QGCECAVADVILKD  479
             C+GQ+L+AVGKQ++ PGW + ++ + A   + EA +   + + + +G  C V +V LK 
Sbjct  421  LCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLSCQVNHVDLKA  480

Query  480  LWTQPPKPFTEGDLIKAMKNVAKLVEDPLLKQKLKDTTGIGTEATRAGIIQGLLDRGYLT  539
            L TQPPKP+T+GDLIKAMK VAKLV DP LKQKLK+TTGIGTEATRA+II+GLL+RGYL 
Sbjct  481  LKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERGYLL  540

Query  540  KQGKALCATPAAFSLIDAVPRAIADPGTTAIWEQALDMVQSGEMSLEEFVAKQAAWMSKQ  599
            K+G+++ A+ AA  LIDAVP AI+DPGTTA+WEQALDM+++G+M+LE FVAKQ++W+++ 
Sbjct  541  KKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWITQL  600

Query  600  VSRCVGMRMTI  610
            V +  +  ++I
Sbjct  601  VQQYRAATLAI  611

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  624 bits (2357),  Expect = 5e-180, Method: Compositional matrix adjust.
 Identities = 386/650 (60%), Positives = 513/650 (79%), Gaps = 8/650 (1%)

Query  1    MRLYICEKPSQARDIARVLQAHRRGDGYLQGIGVTVTWCVGHLLETAPPETYSDQFKRWS  60
            MRL++CEKPSQ++DIARVL A +RG G  +G G  VTWC+GHL+E+APPE+Y++Q+KRWS
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQYKRWS  60

Query  61   LEHLPIIPQHWQLVVKPKVAAQLKAISRLLQACAEVVIATDADREGEMIAREILERCQYQ  120
            LE+LPIIP++W++  K+  AAQLK + +L+   +E+VIATDADREGEMIAREI++ C Y+
Sbjct  61   LEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGYR  120

Query  121  GPILRLWLSALDDASIRRALTALRPGEQTLPLYHCALARSRADWLVGINLSRLFTLLGRR  180
            GPI RLWLSAL+DASIR+AL AL+P+ ++LPLY  ALARSRADWLVG+NLSRLFTLLGR+
Sbjct  121  GPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGRQ  180

Query  181  AGFDGTLPVGRVQTPTLRLVVERDRAIASFVARPFWTVDVVLHADGAEFEARWQPPAAHC  240
            AG+DG L+VGRVQTPTL LVV RDR IA FV+ PFW+++V L ++G  F A W ++ +  
Sbjct  181  AGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGCS  240

Query  241  DDAGHCVDQaaaeqvarrlaaarSVQVERVDVERVTEGPPLPFDLGTLQEVCSAKLGLGA  300
            DDAG+C++QA+A+Q A RL  A S QV  V  ERV E+PPLPFDLGTLQ+VCS +L+L+ 
Sbjct  241  DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALDV  300

Query  301  QETLSVAQALYETHKATTYPRSDCGYLPESMLDEVPRVlkalaaadpalaQRFKEFDPTR  360
            QETL +AQALYETHKATTYPRSD GYLPESML EVP VL A+ ++DP+L   + ++D T+
Sbjct  301  QETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRTQ  360

Query  361  RSRAWNSSKVTAHHGIIPTPVVIPLDQLSERERAVYTLIRARYLAQFLPHHEYLKTQVQL  420
            RSRAWN SKV+AHHGIIPT     L  +S++  AVY LIRA+YLAQFLPH E+ +T  QL
Sbjct  361  RSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQL  420

Query  421  RSQADQVLARGKQIQVRGWKAVIDETDA----SEPTEQTQRLPTLQDGASVAAHDATINT  476
               ++ + A GKQ+ + GW  V+   +A    +E+  ++Q LP+L++G S   ++  +++
Sbjct  421  LCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLSCQVNHVDLKA  480

Query  477  QRTQPPKPYTEGTLVKAMKTIANQVADMRLKQTLKDSIGIGTEATRAAIIQGLIDHGYLT  536
             +TQPPKPYT+G L+KAMK +A+ V+D RLKQ LK++ GIGTEATRA+II+GL+++GYL 
Sbjct  481  LKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERGYLL  540

Query  537  KKKRSLaasaaaHTLIEAVPREVADPVMTALWEQALARIETGQLSVEAFLAKQSAWLTQV  596
            KK R++ AS AA  LI+AVP  ++DP  TA+WEQAL  IE+G++++E+F+AKQS+W+TQ+
Sbjct  541  KKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWITQL  600

Query  597  VRS--QASLNLQLPRSKGPACPVCRSPMRQRKGRTGNFWSCVRYPDCKGT  644
            V+    A+L ++LP   GPACP+C S+ RQR G+TG FWSC RYPDCKGT
Sbjct  601  VQQYRAATLAIKLP--EGPACPLCGSATRQRTGKTGPFWSCCRYPDCKGT  648

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  623 bits (2356),  Expect = 6e-180, Method: Compositional matrix adjust.
 Identities = 384/614 (63%), Positives = 515/614 (84%), Gaps = 0/614 (0%)

Query  1    MQLYLCEKPSQARDIAKVLGANRRGDGCLQGAGVTVTWCIGHLLETAPPDAYDPRYKRWV  60
            M+L+LCEKPSQ++DIA+VLGA +RG GC +GAG  VTWCIGHL+E+APP+AY+ +YKRW 
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQYKRWS  60

Query  61   LADLPIVPERWKMLVKPKTASQFKAVKRLLGECSELVIATDADREGEMIARELVEHCRYR  120
            L +LPI+PERW++  K+ TA+Q+K VK+L+G+ SELVIATDADREGEMIARE+++ C YR
Sbjct  61   LEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGYR  120

Query  121  GPIRRLWLSALDDASIRKALAALKPGAETFNLYHAALGRSRADWLIGMNMSRLFTLLGRQ  180
            GPI+RLWLSAL+DASIRKAL+ALKP++E++ LY AAL+RSRADWL+GMN+SRLFTLLGRQ
Sbjct  121  GPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGRQ  180

Query  181  SGYRGVLPVGRVQTPTLRLVVDRDRSIADFIPVPFWAVDVQLLADGAAFIAQWQAPDDHC  240
            +GY GVL+VGRVQTPTL LVV RDR IA F++VPFW+++V L ++G +F+A W A+D+  
Sbjct  181  AGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGCS  240

Query  241  DDQGRCLDqaraqqaadamrnaasarLLKLKTERQREAAPLPFDLGTLQEVCSKKLGLGA  300
            DD GRCL+QA AQQAAD +R A+SA+++ + TER REA+PLPFDLGTLQ+VCS++L+L+ 
Sbjct  241  DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALDV  300

Query  301  QETLDIAQALYETHKLITYPRSDCGYLPLSQHGEARAIVAALTQADPTLAALQPHLDLSR  360
            QETLDIAQALYETHK  TYPRSD GYLP S  +E  A++AA+  +DP+L +L  +LD ++
Sbjct  301  QETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRTQ  360

Query  361  RSRAWNDAKVGAHHGIIPTaaarglerlagrprTVYELIRARYLAQFLPNHEYDRTQADF  420
            RSRAWND+KV+AHHGIIPT  +  L  +++++ +VY LIRA+YLAQFLP+ E+DRT A++
Sbjct  361  RSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQL  420

Query  421  DCAGQALRAVGKRVVEPGWKRAMPEALAPARGNREaaapqslpalqqgqDYAVGEIKLKD  480
             C+GQ+L+AVGK+V+ PGW + ++ + A   +    + +Q LPAL++G    V ++ LK 
Sbjct  421  LCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLSCQVNHVDLKA  480

Query  481  QQTQPPKPFTEGDLIKAMKNVAKLVDDPRLKQKLKDTTGIGTEATRAGIIQGLLDRGYLV  540
             +TQPPKP+T+GDLIKAMK VAKLV DPRLKQKLK+TTGIGTEATRA+II+GLL+RGYL+
Sbjct  481  LKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERGYLL  540

Query  541  RQGKALAATPAAFSLIDAVPRPIADPGTTAIWEQALDMVQSGEMPLEEFVAKQSAWMSKL  600
            ++G+++ A+ AA  LIDAVP +I+DPGTTA+WEQALDM+++G+M LE FVAKQS+W+++L
Sbjct  541  KKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWITQL  600

Query  601  VERCAGLRMTISGP  614
            V++  +  ++I  P
Sbjct  601  VQQYRAATLAIKLP  614

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  622 bits (2349),  Expect = 2e-179, Method: Compositional matrix adjust.
 Identities = 374/611 (62%), Positives = 504/611 (83%), Gaps = 1/611 (0%)

Query  1    MRLFLCEKPSQAKDIAAALGATRRGDGCWVGANATVTWCIGHLLETAPPDAYDARYKRWV  60
            MRLFLCEKPSQ+KDIA  LGA +RG GC  GA + VTWCIGHL+E+APP+AY+ +YKRW 
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQYKRWS  60

Query  61   LEDLPIIPEKWKMLVKPRTASQFKAVKRLLGEAQELVIATDADREGEMIARELVEHCRYR  120
            LE+LPIIPE+W++  K+ TA+Q+K VK+L+G+A ELVIATDADREGEMIARE+++ C YR
Sbjct  61   LEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGYR  120

Query  121  GPIQRLWLSALDDASIRKALAALKPGADTFSLYHSALGRSRADWLIGMNMSRLFTLLGRQ  180
            GPIQRLWLSAL+DASIRKAL+ALKP++++++LY +AL+RSRADWL+GMN+SRLFTLLGRQ
Sbjct  121  GPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGRQ  180

Query  181  SGYQGVLPVGRVQTPTLRLVVDRDRSIANFVPAPYWAIDVRLLHDNQAFIAQWRAPSDAC  240
            +GY+GVL+VGRVQTPTL LVV RDR IA FV+ P+W+I+V L  + ++F+A W A+ +  
Sbjct  181  AGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGCS  240

Query  241  DDQDRCLNQPLaqqaaeamrsaasarLVKLRTERIREVAPLPFDLGTLQEICSKKLGLGA  300
            DD +RCL+Q+ AQQAA+ +R A+SA++V + TER+RE +PLPFDLGTLQ++CS++L+L+ 
Sbjct  241  DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALDV  300

Query  301  QETLDIAQSLYETHKVITYPRSDCGYLPNSQHGEAAGIIAVLCKADPTLASLSPHLDPQR  360
            QETLDIAQ+LYETHK  TYPRSD GYLP+S  +E ++++A +  +DP+L +L  +LD  +
Sbjct  301  QETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRTQ  360

Query  361  RSRAWNDGKVTAHHGIIPTAAVRGVERLTGKPRAVYTLIRARYLAQFLPSHEYDRTQADF  420
            RSRAWND+KV+AHHGIIPT     +  +++K+ AVY LIRA+YLAQFLP  E+DRT A++
Sbjct  361  RSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQL  420

Query  421  DCAGHALRAVGKQIVEPGWKRAMPEALAPAKGREapapqplpalF-QGCECTVAEVILKD  479
             C+G++L+AVGKQ++ PGW + ++ + A   + EA +   + + + +G  C V +V LK 
Sbjct  421  LCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLSCQVNHVDLKA  480

Query  480  LWTQPPKPFTEGDLIKAMKNVAKLVEDPLLKQKLKDTTGIGTEATRAGIIQGLLDRGYLT  539
            L TQPPKP+T+GDLIKAMK VAKLV DP LKQKLK+TTGIGTEATRA+II+GLL+RGYL 
Sbjct  481  LKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERGYLL  540

Query  540  KQGKALCAAPAAFSLIDAVPRAIADPGTTAIWEQALDMVQNGEMSLEEFVAKQAAWMSKQ  599
            K+G+++ A+ AA  LIDAVP AI+DPGTTA+WEQALDM++ G+M+LE FVAKQ++W+++ 
Sbjct  541  KKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWITQL  600

Query  600  VSRCVGMRMSI  610
            V +  +  ++I
Sbjct  601  VQQYRAATLAI  611

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  617 bits (2331),  Expect = 6e-178, Method: Compositional matrix adjust.
 Identities = 378/650 (59%), Positives = 516/650 (80%), Gaps = 5/650 (0%)

Query  1    MRLFICEKPSQARDIARVLQASRRGDGYLEGQNLTVTWCVGHLLETAPPETYGD-YKRWS  59
            MRLF+CEKPSQ++DIARVL A++RG G  +G    VTWC+GHL+E+APPE+YG+ YKRWS
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQYKRWS  60

Query  60   LDDLPIIPSQWKLVSKPKVAGQLNAISQLLRTCSEVVIATDADREGEMIAREILERCQYH  119
            L++LPIIP +W++ +K+  A+QL+ + QL+   SE+VIATDADREGEMIAREI++ C Y+
Sbjct  61   LEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGYR  120

Query  120  GPILRLWLSALDEASIRRALSALRPGEQTLSLYHCALARSRADWLVGINLSRLFTLLGRR  179
            GPI RLWLSAL++ASIR+AL+AL+P+ ++L+LY  ALARSRADWLVG+NLSRLFTLLGR+
Sbjct  121  GPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGRQ  180

Query  180  AGFDGLLPVGRVQTPTLRLVVERDRAIASFVPQPFWTVDAHLEQDGIRFHARWQAPTAVS  239
            AG+DG+L+VGRVQTPTL LVV RDR IA FV+ PFW+++  L  +G  F A W A+ + S
Sbjct  181  AGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGCS  240

Query  240  DAVGRCIDEtaaqqalrrltqaGTAQIDSVEVERGREGPPLPFDLGTLQEICSAKLGLGA  299
            D  GRC+++++AQQA  RL  AG+AQ+ +V  ER RE+PPLPFDLGTLQ++CS +L+L+ 
Sbjct  241  DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALDV  300

Query  300  QETLATAQALYETHKATTYPRTDCGYLPESMLDEVPRVlhalaaaapslgavlKEIDPSR  359
            QETL  AQALYETHKATTYPR+D GYLPESML EVP VL A+ ++ PSL ++L ++D ++
Sbjct  301  QETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRTQ  360

Query  360  RSRAWNSSKITAHHGIIPTAVTLDLAQLSERERAVYTLIRARYLAQLMPEHEYLKTQALL  419
            RSRAWN SK++AHHGIIPT    +LA +S++  AVY LIRA+YLAQ++P+ E+ +T A L
Sbjct  361  RSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQL  420

Query  420  HSQADQLVARGKQVLVRGWKAVINEADGAEPAEQA----QRLPTLRESATVLLIDATLNA  475
               ++ L A GKQV++ GW  V+  +++ ++  +A    Q LP+LRE+ +  + +  L+A
Sbjct  421  LCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLSCQVNHVDLKA  480

Query  476  QQTQPPKAYTEGTLVKAMKTIASQVAEPRLKQKLKDSCGLGTEATRAAIIQGLIDHGYLT  535
             +TQPPK+YT+G L+KAMK +A  V++PRLKQKLK++ G+GTEATRA+II+GL+++GYL 
Sbjct  481  LKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERGYLL  540

Query  536  KKKRSLaasaaaHTLIEAVPPEVADPVMTALWEQALDRIESGQLSVETFLAKQAEWLTRL  595
            KK R++ AS AA  LI+AVP+ ++DP  TA+WEQALD IE+G++++ETF+AKQ+ W+T+L
Sbjct  541  KKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWITQL  600

Query  596  VRSNATLTLRPPPSKGPFCPVCRSTMRQRKGRTGNFWSCIRYPECKGTKP  645
            V+   + TL    + GP CP+C S+ RQR G+TG FWSC RYP+CKGT P
Sbjct  601  VQQYRAATLAIKLPEGPACPLCGSATRQRTGKTGPFWSCCRYPDCKGTLP  650

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  601 bits (2270),  Expect = 4e-173, Method: Compositional matrix adjust.
 Identities = 362/594 (61%), Positives = 491/594 (83%), Gaps = 1/594 (0%)

Query  1    MLGASRRGDGCWLGNGVTVTWCIGHLLETAPPDTYDAKYKRWVLADLPIVPQKWKMLVKP  60
            +LGA++RG GC  G G  VTWCIGHL+E+APP++Y+ +YKRW L +LPI+P++W++  K+
Sbjct  18   VLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQYKRWSLEQLPIIPERWRVEPKA  77

Query  61   KTASQFKAVKRLLGEAQELIIATDADREGEMIARELVEHCRYRGPIQRLWLSALDDASIR  120
             TA+Q+K VK+L+G+A EL+IATDADREGEMIARE+++ C YRGPIQRLWLSAL+DASIR
Sbjct  78   ATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGYRGPIQRLWLSALNDASIR  137

Query  121  KALAALKPGAETFSLYHSALGRSRADWLIGMNMSRLFTLLGRQSGYQGVLPVGRVQTPTL  180
            KAL+ALKP++E+++LY +AL+RSRADWL+GMN+SRLFTLLGRQ+GY+GVL+VGRVQTPTL
Sbjct  138  KALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGRQAGYDGVLSVGRVQTPTL  197

Query  181  RLVVDRDRSIADFVPVAYWAIDVDLRHDAITFTAQWRAAEDACDDQGRCLNPQLardaaq  240
             LVV RDR IA FV+V++W+I+V+L  ++ +F A W AA++  DD GRCL+   A++AA+
Sbjct  198  ALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGCSDDAGRCLQQATAQQAAD  257

Query  241  amtqaasarLVKLRTERMREVAPLPFDLGTLQEVCSKKLGLGAQETLDIAQSLYETHKVI  300
             +  A+SA++V + TER+RE +PLPFDLGTLQ+VCS++L+L+ QETLDIAQ+LYETHK  
Sbjct  258  RLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALDVQETLDIAQALYETHKAT  317

Query  301  TYPRSDCGYLPLSQHSDAPKILAALGRADAAVNELMPHIDPQRRSRAWNDAKVSAHHGII  360
            TYPRSD GYLP S  ++ P +LAA+  +D+++  L+ ++D  +RSRAWND+KVSAHHGII
Sbjct  318  TYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRTQRSRAWNDSKVSAHHGII  377

Query  361  PTGAGKDLGQLAGKQRAVYTLIRARYLAQFLPNHEYDRTQADFDCAGQALRAVGKVVIEP  420
            PT    +L+ +++K  AVY LIRA+YLAQFLP+ E+DRT A++ C+GQ+L+AVGK VI P
Sbjct  378  PTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQLLCGGQTLQAVGKQVIIP  437

Query  421  GWKRALPEALA-PAKGREapapqalptlaqGRDYVVARVNLKDLWTQPPKPFTEGDLIKA  479
            GW + L+ + A  A G   P +Q LP+L +G    V +V+LK L TQPPKP+T+GDLIKA
Sbjct  438  GWHQVLAGPEADNADGEAVPRSQVLPALREGLSCQVNHVDLKALKTQPPKPYTQGDLIKA  497

Query  480  MKNVAKLVQDPLLKQKLKDTTGIGTEATRAGIIQGLLDRGYLVKNGKALSATPAAFSLID  539
            MK VAKLV DP LKQKLK+TTGIGTEATRA+II+GLL+RGYL+K+G+++ A+ AA  LID
Sbjct  498  MKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERGYLLKKGRTVRASDAAGRLID  557

Query  540  AVPRAIADPGTTAIWEQALDMVQSGEMSLEEFVAKQAAWMSKQVARCNGMRMTI  593
            AVP AI+DPGTTA+WEQALDM+++G+M+LE FVAKQ++W+++ V +  +  ++I
Sbjct  558  AVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWITQLVQQYRAATLAI  611

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  592 bits (2235),  Expect = 2e-170, Method: Compositional matrix adjust.
 Identities = 361/577 (63%), Positives = 482/577 (84%), Gaps = 0/577 (0%)

Query  2    TVTWCIGHLLETAPPDAYDPRYKRWVLADLPIVPERWKMLVKPKTASQFKAVKRLLGECR  61
             VTWCIGHL+E+APP+AY+ +YKRW L +LPI+PERW++  K+ TA+Q+K VK+L+G+  
Sbjct  35   VVTWCIGHLIEAAPPEAYGEQYKRWSLEQLPIIPERWRVEPKAATAAQLKIVKQLVGQAS  94

Query  62   ELVIATDADREGEMIARELVEHCRYRGPIRRLWLSALDDASIRKALAALKPGAETFNLYH  121
            ELVIATDADREGEMIARE+++ C YRGPI+RLWLSAL+DASIRKAL+ALKP++E++ LY 
Sbjct  95   ELVIATDADREGEMIAREIIDLCGYRGPIQRLWLSALNDASIRKALGALKPSSEALPLYA  154

Query  122  AALGRSRADWLIGMNMSRLFTLLGRQSGYRGVLPVGRVQTPTLRLVVDRDRSIADFIPVP  181
            AAL+RSRADWL+GMN+SRLFTLLGRQ+GY GVL+VGRVQTPTL LVV RDR IA F++VP
Sbjct  155  AALARSRADWLVGMNLSRLFTLLGRQAGYDGVLSVGRVQTPTLALVVTRDREIARFVSVP  214

Query  182  FWAIDVQLLADGAAFTAQWQAPDDLCDDQGRCLDqaraqqaadamrnaasarLLKLKTER  241
            FW+I+V L ++G +F A W A+D+  DD GRCL+QA AQQAAD +R A+SA+++ + TER
Sbjct  215  FWSIEVGLSTGGHSFLATWIAADGCSDDAGRCLQQATAQQAADRLRVAGSAQVVAVTTER  274

Query  242  QREAAPLPFDLGTLQEVCSKKLGLGAQETLDIAQALYETHKLITYPRSDCGYLPLSQLGE  301
             REA+PLPFDLGTLQ+VCS++L+L+ QETLDIAQALYETHK  TYPRSD GYLP S L+E
Sbjct  275  VREAPPLPFDLGTLQDVCSRQLALDVQETLDIAQALYETHKATTYPRSDSGYLPESMLAE  334

Query  302  ARAIVAALTQADPTLAALQPHLDLSRRSRAWNDAKVGAHHGIVPTaaarglerlagrpra  361
              A++AA+  +DP+L +L  +LD ++RSRAWND+KV+AHHGI+PT  +  L  +++++ A
Sbjct  335  VPAVLAAMLTTDPSLRPLLEQLDRTQRSRAWNDSKVSAHHGIIPTLEPANLAAISDKALA  394

Query  362  VYELIRARYLAQFLPNHEYDRTQADFDCAGQALRAVGKRVVEPGWKRAMPEALAPARGNR  421
            VY LIRA+YLAQFLP+ E+DRT A++ C+GQ+L+AVGK+V+ PGW + ++ + A   +  
Sbjct  395  VYRLIRAHYLAQFLPHYEFDRTTAQLLCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGE  454

Query  422  EAHAPQSLPALQQGQDYAVGEITLKDQQTQPPKPFTEGDLIKAMKNVAKLVDDPRLKQKL  481
                +Q LPAL++G    V ++ LK  +TQPPKP+T+GDLIKAMK VAKLV DPRLKQKL
Sbjct  455  AVPRSQVLPALREGLSCQVNHVDLKALKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKL  514

Query  482  KDTTGIGTEATRAGIIQGLLDRGYLVRQGKALAATPAAFSLIDAVPRPIADPGTTAIWEQ  541
            K+TTGIGTEATRA+II+GLL+RGYL+++G+++ A+ AA  LIDAVP +I+DPGTTA+WEQ
Sbjct  515  KETTGIGTEATRASIIKGLLERGYLLKKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQ  574

Query  542  ALDMVQSGEMPLEEFVAKQSAWMSKLVERCAGLRMTI  578
            ALDM+++G+M LE FVAKQS+W+++LV++  +  ++I
Sbjct  575  ALDMIEAGDMTLETFVAKQSTWITQLVQQYRAATLAI  611

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  590 bits (2229),  Expect = 7e-170, Method: Compositional matrix adjust.
 Identities = 333/668 (50%), Positives = 499/668 (75%), Gaps = 3/668 (0%)

Query  1    MKLFLCEKPSQGRDIAAVLGATKKMPGHQTGNGVCVTWGFGHLLEQASPDAYGEQFGVPW  60
            M+LFLCEKPSQG+DIA VLGA ++ +G   G G  VTW +GHL+E A+P+AYGEQ+   W
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQYK-RW  59

Query  61   RTDVLPVLPTMWQMRVKPDAAAQFSVIQKLLKQADTVVIATDADREGEVIAREILDYCHY  120
              + LP++P  W++  K+ +AAQ+ ++++L+ QA  +VIATDADREGE+IAREI+D C Y
Sbjct  60   SLEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGY  119

Query  121  QGKVERLWLSALDEASVRAALATIKPGSTTLPYYLAGLGRARADWQIGMNMTRLYSVKAR  180
            +G ++RLWLSAL++AS+R AL+++KP+S +LP Y A+L+R+RADW +GMN++RL+++ +R
Sbjct  120  RGPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGR  179

Query  181  ENGYGSVLSVGRVQTPTLNLIVVRDRDIVQFVPKPYWNVVAQLAAGGIAFQAQWVPAEAY  240
            + GY++VLSVGRVQTPTL L+V RDR+I +FV+ P+W++   L++GG +F A W++A++ 
Sbjct  180  QAGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGC  239

Query  241  CDEEKRCINPTAAQQVVQLCQKTGQATVAEVETKRETESAPLAFDLGTLQQACSRRFGYG  300
             D+  RC++ ++AQQ  +  + +G A V  V T R  E++PL+FDLGTLQ+ CSR+++ +
Sbjct  240  SDDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALD  299

Query  301  AQQVLDIAQALYETYKATTYPRTDCGYLPTSMRGEIGQVMSSIQQSDPALSAIISRLDMK  360
             Q+ LDIAQALYET KATTYPR+D GYLP SM +E+  V++++  +DP+L +++ +LD  
Sbjct  300  VQETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRT  359

Query  361  HVSRIWNDKKITAHHGIIPTKQPCDLAKMSEQERNVYQLIRLHYLAQFLPNHEVDATRVS  420
            + SR WND K++AHHGIIPT +P +LA +S++   VY+LIR HYLAQFLP+ E D T   
Sbjct  360  QRSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQ  419

Query  421  LHCGGQLFKTSGKAVVVAGWKSLFgkdadedagdagdkaR--LPAMAKGSLCQVTGAEAK  478
            L CGGQ +++ GK V+++GW  +++    ++A++ +      LPA+  G  CQV   + K
Sbjct  420  LLCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLSCQVNHVDLK  479

Query  479  PQQTKPPEHYTEGTLIAAMKNAAQFVTDPRLKKILKENAGLGTEATRAGVIETLLKRGFV  538
            + +T+PP  YT+G LI AMK  A++VTDPRLK+ LKE +G+GTEATRA++I  LL RG++
Sbjct  480  ALKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERGYL  539

Query  539  VKKGKHLLATPIAADLMAVLPAQLKDPGMTALWEQSLDDIAEGRMSLDDFMAKQSAWTMQ  598
            +KKG+ + A+  A+ L+  +PA + DPG TA+WEQ+LD I  G M+L+ F+AKQS+W  Q
Sbjct  540  LKKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWITQ  599

Query  599  LVAKGQHQTVKITLPPSPPCPICGGVTRQRTGKSGSFWGCVNYPDCNGIVNVGAKKPGRR  658
            LV + +  T+ I LP +P+CP+CG+ TRQRTGK+G+FW+C  YPDC+G + V   + +  
Sbjct  600  LVQQYRAATLAIKLPEGPACPLCGSATRQRTGKTGPFWSCCRYPDCKGTLPVQNGRQASA  659

Query  659  RKSPAKKS  666
            ++S ++K+
Sbjct  660  KRSTSRKP  667

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  590 bits (2229),  Expect = 7e-170, Method: Compositional matrix adjust.
 Identities = 333/668 (50%), Positives = 499/668 (75%), Gaps = 3/668 (0%)

Query  1    MKLFLCEKPSQGRDIAAVLGATKKMPGHQTGNGVCVTWGFGHLLEQASPDAYGEQFGVPW  60
            M+LFLCEKPSQG+DIA VLGA ++ +G   G G  VTW +GHL+E A+P+AYGEQ+   W
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQYK-RW  59

Query  61   RTDVLPVLPTMWQMRVKPDAAAQFSVIQKLLKQADTVVIATDADREGEVIAREILDYCHY  120
              + LP++P  W++  K+ +AAQ+ ++++L+ QA  +VIATDADREGE+IAREI+D C Y
Sbjct  60   SLEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGY  119

Query  121  QGKVERLWLSALDEASVRAALATIKPGSTTLPYYLAGLGRARADWQIGMNMTRLYSVKAR  180
            +G ++RLWLSAL++AS+R AL+++KP+S +LP Y A+L+R+RADW +GMN++RL+++ +R
Sbjct  120  RGPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGR  179

Query  181  ENGYGSVLSVGRVQTPTLNLIVVRDRDIVQFVPKPYWNVVAQLAAGGIAFQAQWVPAEAY  240
            + GY++VLSVGRVQTPTL L+V RDR+I +FV+ P+W++   L++GG +F A W++A++ 
Sbjct  180  QAGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGC  239

Query  241  CDEEKRCINPTAAQQVVQLCQKTGQATVAEVETKRETESAPLAFDLGTLQQACSRRFGYG  300
             D+  RC++ ++AQQ  +  + +G A V  V T R  E++PL+FDLGTLQ+ CSR+++ +
Sbjct  240  SDDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALD  299

Query  301  AQQVLDIAQALYETYKATTYPRTDCGYLPTSMRGEIGQVMSSIQQSDPALSAIISRLDMK  360
             Q+ LDIAQALYET KATTYPR+D GYLP SM +E+  V++++  +DP+L +++ +LD  
Sbjct  300  VQETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRT  359

Query  361  HVSRIWNDKKITAHHGIIPTKQPCDLAKMSEQERNVYQLIRLHYLAQFLPNHEVDATRVS  420
            + SR WND K++AHHGIIPT +P +LA +S++   VY+LIR HYLAQFLP+ E D T   
Sbjct  360  QRSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQ  419

Query  421  LHCGGQLFKTSGKAVVVAGWKSLFgkdadedagdagdkaR--LPAMAKGSLCQVTGAEAK  478
            L CGGQ +++ GK V+++GW  +++    ++A++ +      LPA+  G  CQV   + K
Sbjct  420  LLCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLSCQVNHVDLK  479

Query  479  PQQTKPPEHYTEGTLIAAMKNAAQFVTDPRLKKILKENAGLGTEATRAGVIETLLKRGFV  538
            + +T+PP  YT+G LI AMK  A++VTDPRLK+ LKE +G+GTEATRA++I  LL RG++
Sbjct  480  ALKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERGYL  539

Query  539  VKKGKHLLATPIAADLMAVLPAQLKDPGMTALWEQSLDDIAEGRMSLDDFMAKQSAWTMQ  598
            +KKG+ + A+  A+ L+  +PA + DPG TA+WEQ+LD I  G M+L+ F+AKQS+W  Q
Sbjct  540  LKKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWITQ  599

Query  599  LVAKGQHQTVKITLPPSPPCPICGGVTRQRTGKSGSFWGCVNYPDCNGIVNVGAKKPGRR  658
            LV + +  T+ I LP +P+CP+CG+ TRQRTGK+G+FW+C  YPDC+G + V   + +  
Sbjct  600  LVQQYRAATLAIKLPEGPACPLCGSATRQRTGKTGPFWSCCRYPDCKGTLPVQNGRQASA  659

Query  659  RKSPAKKS  666
            ++S ++K+
Sbjct  660  KRSTSRKP  667

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  580 bits (2189),  Expect = 1e-166, Method: Compositional matrix adjust.
 Identities = 328/674 (49%), Positives = 489/674 (73%), Gaps = 6/674 (0%)

Query  1    MKLFLCEKPSQGRDIAVVLGATKRGQGYLTGPGVTVTWAVGHLLETASPEVYGEQYGAPW  60
            M+LFLCEKPSQG+DIA VLGA +RG G   G+G  VTW +GHL+E+A+PE YGEQY   W
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQY-KRW  59

Query  61   RASVLPILPASWQMVVKKETADQFTVICRLLKQADEVVIATDADREGEVIARELLDYCQF  120
                LPI+P  W++  K  TA Q+ ++ +L+ QA E+VIATDADREGE+IARE++D C +
Sbjct  60   SLEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGY  119

Query  121  QGKISRLWLSALDEVSIRAALANILPGEQTASLYLAGLGRARADWLIGMNFTRLYTVKAR  180
            +G I RLWLSAL++ SIR AL+ + P+ ++ +LY A+L+R+RADWL+GMN++RL+T+ +R
Sbjct  120  RGPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGR  179

Query  181  ECGYSDILSIGRVQTPSLALVVFRDREIIAFTAKPYWQVVADLQFDGRIFRADWVPAATY  240
            + GY ++LS+GRVQTP+LALVV RDREI  F + P+W +  +L  +G+ F A W++A   
Sbjct  180  QAGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGC  239

Query  241  CDEEKRCIHQNVAQTVVKLCQQTGTATVLEINTKREKHAAPLAFDLGSLQQLCSKKWSMG  300
             D+  RC++Q  AQ      + +G+A V+ + T R ++A+PL+FDLG+LQ++CS++ +++
Sbjct  240  SDDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALD  299

Query  301  AQQVLNIAQNLYETHKATTYPRTDCGYLPTAMQAEIPQVLDAVVKSDPAMRIVVDSLDRT  360
             Q+ L+IAQ LYETHKATTYPR+D GYLP +M AE+P VL A++ +DP++R +++ LDRT
Sbjct  300  VQETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRT  359

Query  361  LISRIWNDKKITAHHGIIPTKQPCDMNKMTDDERKVYQLIRQHYLLQFLPLHEMDITEAT  420
              SR WND K++AHHGIIPT +P ++  ++D    VY+LIR HYL QFLP  E D T A 
Sbjct  360  QRSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQ  419

Query  421  FDIGGQLFRTRGNVVIVPGWKVLFSAGKDESASIGKDDSLGESLPSMVKGNQCQVNEATL  480
            +  GGQ +++ G+ VI+PGW  ++++   ++A  G   + ++ LP++  G  CQVN+  L
Sbjct  420  LLCGGQTLQAVGKQVIIPGWHQVLAGPEADNAD-GEAVPRSQVLPALREGLSCQVNHVDL  478

Query  481  RMLQTQPSAHFTEGTLIAAMKNAAAFVSDPQLKKVLKDNAGLGTEATRAGVLDTLFKRGY  540
            + L+TQP+  +T+G LI AMK  A +V+DP+LK+ LK+ +G+GTEATRA+++  L+ RGY
Sbjct  479  KALKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERGY  538

Query  541  LTKKGKYIHATQIASELIAALPTALTNPGLTALWEQALDDIAQGQAELPDFMARQVQWTQ  600
            L KKG+ ++A++ A+ LI A+P+A+T+PG TA+WEQALD I  G+  L  F+A+Q  W  
Sbjct  539  LLKKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWIT  598

Query  601  YLVEQVQAQKVVITPPPSLPCPVCGGVTRQRQGKNGVFWGCIKYPECSGVVSTVDGK---  657
             LV+Q +A  + I  P + +CP+CG+ TRQR GK G FW+C +YP+C G ++  +G+   
Sbjct  599  QLVQQYRAATLAIKLPEGPACPLCGSATRQRTGKTGPFWSCCRYPDCKGTLPVQNGRQAS  658

Query  658  -RKTRSARHKNIPK  670
             +++ S + ++IPK
Sbjct  659  AKRSTSRKPRQIPK  672

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  579 bits (2185),  Expect = 2e-166, Method: Compositional matrix adjust.
 Identities = 334/664 (51%), Positives = 485/664 (74%), Gaps = 15/664 (2%)

Query  1    MKLILCEKPSQGRDIGKFIGATKRGEGYLSSPDQQTFVTWGIGHLVEQAEPQDYDESYKK  60
            M+L+LCEKPSQG+DI++ +GA +RG G  ++++  T VTW IGHL+E A P+ Y+E YK+
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAG--TVVTWCIGHLIEAAPPEAYGEQYKR  58

Query  61   WIFDNLPIIPDKWIMKVKKETAKQYKIVMGLIKKANHIVIATDPDREGEVIARELLDMAN  120
            W +++LPIIP++W +  K  TA Q KIV  L+ +A+++VIATD+DREGE+IARE++D+  
Sbjct  59   WSLEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCG  118

Query  121  YKGKVQRLWLSALDDGSIRKALANLKSDAETKPLYAAGLARGRADWLVGMNLTRLFTLIA  180
            Y+G +QRLWLSAL+D+SIRKAL+ LK+ +E+ PLYAA+LAR+RADWLVGMNL+RLFTL++
Sbjct  119  YRGPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLG  178

Query  181  QKQGYQGVMSVGRVQSPTLAIVVQRDREIENFVSKPFYRLKVNL----DGFCAYWQPTES  236
            ++ GY+GV+SVGRVQ+PTLA+VV RDREI  FVS PF  + V L    ++F A W ++++
Sbjct  179  RQAGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADG  238

Query  237  VCDDEGRCIDYSVITQVQRQL--SKTLKIDNIETKRKKEMPPLAFDLGTLQQTCSRLFGM  294
              DD GRC++ +   Q   +L  + + ++  + T R +E PPL+FDLGTLQ+ CSR +++
Sbjct  239  CSDDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLAL  298

Query  295  GAAQVLKIAQSLYETHKATTYPRTDCGYLPESMIDEIPLVLKAVSESDPQVRNIVAKLDI  354
            +  + L IAQ+LYETHKATTYPR+D GYLPESM+ E+P VL A+  +DP +R ++ +LD 
Sbjct  299  DVQETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDR  358

Query  355  SLRSRVWNDSKITAHHGIIPTTQKVDLSKMSDDELKVYQLVRKHYFAQFLPLYEEDNTSV  414
            + RSR WNDSK++AHHGIIPT +  +L+ +SD  L VY+L+R HY+AQFLP YE D T+ 
Sbjct  359  TQRSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTA  418

Query  415  LLSGNEQTFVSKGKQVIKIGWKSLFQQDRNEDDEEQS------LPSLRQGQSCNVVDSEV  468
             L    QT+ + GKQVI  GW  ++     ++ + ++      LP+LR+G SC+V + ++
Sbjct  419  QLLCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLSCQVNHVDL  478

Query  469  LTLKTTPPKHYTEGTLIAAMKNAARFVTDARLKQRLRETEGLGTEATRAEVIETLFKRGY  528
             +LKT PPK YT+G LI AMK  A++VTD+RLKQ+L+ET G+GTEATRA +I  L+ RGY
Sbjct  479  KALKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERGY  538

Query  529  LEKKRKEIVATSAGRSLIDGLPDIIKDPGMTALWEQALNDIASGKMLLQDFMAKQNQFIS  588
            L KK + + A+ A+  LID++P  I DPG TA+WEQAL+ I +G M L+ F+AKQ+  I+
Sbjct  539  LLKKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWIT  598

Query  589  HVVKSMIGSGSVAIQVKAEKICPKCGAAMRRRKGKNGDFWGCSNYPTCTAIENIGSRKRV  648
            ++V+    ++++AI++     CP CG+A R+R GK G FW+C  YP C +   + + ++ 
Sbjct  599  QLVQQ-YRAATLAIKLPEGPACPLCGSATRQRTGKTGPFWSCCRYPDCKGTLPVQNGRQA  657

Query  649  GKSR  652
            +  R
Sbjct  658  SAKR  661

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  578 bits (2184),  Expect = 2e-166, Method: Compositional matrix adjust.
 Identities = 345/670 (52%), Positives = 490/670 (74%), Gaps = 2/670 (0%)

Query  1    MRLFLCEKPSQGRDIAAVLGATKRGTGFLQGPGVTVTWAVGHLLETASPEAYGTQFARPW  60
            MRLFLCEKPSQG+DIA VLGA +RG+G  +G+G  VTW +GHL+E+A+PEAYG Q+ R W
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQYKR-W  59

Query  61   NIHALPVLPAQWQMVVKKETEDQFKAIAKLLKQVDEVVIATDADREGEVIARELLDFCQW  120
            +++ LP++P +W++  K  T  Q+K + +L+ Q  E+VIATDADREGE+IARE++D+C  
Sbjct  60   SLEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGY  119

Query  121  RGPVNRLWLSALDEPSIRNGLNNIKPGNETLALYYAGLGRARADWLTGMNLTRLYTLKAR  180
            RGP++RLWLSAL+++SIR++L  +KP++E+L+LY A+L+R+RADWL GMNL+RL+TL +R
Sbjct  120  RGPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGR  179

Query  181  EKGFDGVLSVGRVQTPTLALVVNRDREIAIFVPKPYWQVNAALQACGMAFVARWVPAKMY  240
            + G+DGVLSVGRVQTPTLALVV RDREIA FV+ P+W ++ +L + G +F+A W++A   
Sbjct  180  QAGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGC  239

Query  241  TDEEKRCVHQGIAQQVAQLCRQSGQAQVIEQEKKRETEAAPLAFSLGALQQACGKLWDMS  300
            +D+  RC++Q+ AQQ A+  R +G AQV+     R  EA+PL+F LG+LQ+ C++   + 
Sbjct  240  SDDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALD  299

Query  301  PQQVLDTAQSLYETHKATTYPRTDCGFLPESMREEIPLVLAALAKTDPSLTTTIATLDPR  360
             Q+ LD AQ+LYETHKATTYPR+D G+LPESM  E+P VLAA+  TDPSL   +  LD  
Sbjct  300  VQETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRT  359

Query  361  FVSRIWNDKKITAHHGIIPTKHASDMGNMNDVEKRVYELIRRHYLAQFLPLYERDVTRLD  420
              SR WND K++AHHGIIPT ++++++ ++D    VY LIR HYLAQFLP YE D T  +
Sbjct  360  QRSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQ  419

Query  421  LSIGGQLFRTTGQVVVVPGWKVLFSSATDRKGNAQG-DEDNALPSLNKGDVCTVTVAEVK  479
            L  GGQ +++ G+ V++PGW  +++++   ++++++    + LP+L  G  C V   ++K
Sbjct  420  LLCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLSCQVNHVDLK  479

Query  480  DLKTKAPLYFTFDTLIAAMMNAASYVTDLQLKKVLKENAGLGTEATRASIIDTLLKRGYI  539
             LKT++P  +T + LI AM   A  VTD +LK+ LKE +G+GTEATRASII  LL RGY+
Sbjct  480  ALKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERGYL  539

Query  540  VMNRRYLRATEVAMDLMDALPAPLKEPGMTALWEQALDEVAAGRMRLEDFMARQTGWTRQ  599
            + + R +RA++ A  L+DA+PA++ +PG TA+WEQALD + AG M LE F+A+Q+ W  Q
Sbjct  540  LKKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWITQ  599

Query  600  LVAQGLAQNMVIRLPPTPVCPLCGSKTRLRRGEKKAFYRCEKYPSCKGVVNVPDQVKRKS  659
            LV Q  A  + I+LP  P CPLCGS TR R G   +F  C +YP CKG + V +  +  +
Sbjct  600  LVQQYRAATLAIKLPEGPACPLCGSATRQRTGKTGPFWSCCRYPDCKGTLPVQNGRQASA  659

Query  660  AKSTSRKPKQ  669
             +STSRKP+Q
Sbjct  660  KRSTSRKPRQ  669

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  576 bits (2174),  Expect = 1e-165, Method: Compositional matrix adjust.
 Identities = 337/656 (52%), Positives = 486/656 (75%), Gaps = 11/656 (1%)

Query  3    RLFLCEKPTQARDIAKVLGASEKGNGCLKGRGITVTWGFGHLLEQANPEAYDPALKRWSM  62
            RLFLCEKP+Q++DIA+VLGA+++G+GC +G G  VTW +GHL+E A PEAY+   KRWS+
Sbjct  2    RLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQYKRWSL  61

Query  63   ESLPILPTQWKLEVKPSAKKQFTVVKKLLSSASEVVIATDADREGEMIAREILEACQFSG  122
            E LPI+P +W++E K+++  Q+ +VK+L++ ASE+VIATDADREGEMIAREI++ C + G
Sbjct  62   EQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGYRG  121

Query  123  GVSRLWLPALDEASIRKALGDIRPGESTRLLYHAALGRSRADWLVGMNLTRAFTMRAKQL  182
             + RLWL+AL++ASIRKALG ++P+  +  LY AAL+RSRADWLVGMNL+R FT+ ++Q 
Sbjct  122  PIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGRQA  181

Query  183  GYDLLLSVGRVQTPVLKLVVDRDREIANFVPKPFWEVVAVFQAEGGTFQAKWQPADDDVL  242
            GYD +LSVGRVQTP L LVV RDREIA FV+ PFW +   + + G +F A W +A D+  
Sbjct  182  GYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAA-DGCS  240

Query  243  DESGRCINQSAAQAVVARCQ-GLPGQVTTLETTRKREAPPLAMDLGTLQQTCSKRWGYGA  301
            D++GRC++Q++AQ    R + + ++QV ++ T R REAPPL+ DLGTLQ+ CS++ + + 
Sbjct  241  DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALDV  300

Query  302  QQVLDIAQALYETHKATTYPRTDCRYLPLSQLDDAQQVVTALLTSDGELAPVVQSLDLTR  361
            Q+ LDIAQALYETHKATTYPR+D  YLP S L +   V++A+LT+D  L P+++ LD T+
Sbjct  301  QETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRTQ  360

Query  362  KSRVWNDSKITAHHGIIPTTSPCDTSKMSEAEWNVYDLVRRHYLAQFLPPHEYDHTDVAL  421
            +SR WNDSK++AHHGIIPT  P + + +S+    VY L+R HYLAQFLP  E+D+T   L
Sbjct  361  RSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQL  420

Query  422  EVAGERFATTGRQVQVEGWKVLFRNVQQDDAAGDEATAKTSSQALPPLQAHANVPQSSLD  481
              +G+ + + G+QV + GW  ++   + D+A G+       SQ LP+L+   +   + +D
Sbjct  421  LCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAV---PRSQVLPALREGLSCQVNHVD  477

Query  482  LVSKTTTPPKPFAEGTLIGAMKNAARFEPNPKLKARLKESAGIGTEATRAGIIETLLKRK  541
            L +  T PPKP+++G LI AMK  A++  +P+LK +LKE++GIGTEATRA+II  LL R 
Sbjct  478  LKALKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERG  537

Query  542  FLTKKGRAIVATATGRQLIDALPEVVTNPGMTALWEQALDSVAAGELSLEDFMAKQQTLV  601
            +L KKGR++ A+ ++ +LIDA+P  +T+PG TA+WEQALD + AG+++LE F+AKQ T +
Sbjct  538  YLLKKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWI  597

Query  602  ERLIEQAKSAT--INLPQEPAKSKACPECGAPMKKRKNDYGSFWGCTKYPDCKGMV  655
             +L++Q ++AT  I+LP+ P    ACP CG++ ++R    G+FW+C +YPDCKG +
Sbjct  598  TQLVQQYRAATLAIKLPEGP----ACPLCGSATRQRTGKTGPFWSCCRYPDCKGTL  649

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  566 bits (2136),  Expect = 1e-162, Method: Compositional matrix adjust.
 Identities = 330/650 (51%), Positives = 474/650 (73%), Gaps = 4/650 (0%)

Query  1    MRLVLCEKPSQGRDIAKFLGATQRGEGFLNGPGVTVTWARGHLLETAEPEVYGEQYGKPW  60
            MRL LCEKPSQG+DIA+ LGA QRG G  NG+G  VTW  GHL+E+A PE YGEQY K W
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQY-KRW  59

Query  61   RTDVLPLLPQQWKLVVKADAKAQFAVINRLLKQVDEVVIATDADREGEVIARELLDYCKF  120
              + LP++P++W++  KA + AQ+ ++++L+ Q  E+VIATDADREGE+IARE++D C +
Sbjct  60   SLEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGY  119

Query  121  QGRVFRLWMSALDDASIRSALADLWPSSRTESLYYAGVGRSRADWLIGMNLTRLFTLLGR  180
            +G + RLW+SAL+DASIR AL+ L PSS + +LY A+++RSRADWL+GMNL+RLFTLLGR
Sbjct  120  RGPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGR  179

Query  181  EAGIGNVLSVGRVQTPTLAIVVKRDREIDNFVSKPYFEVIATMAVNGVLFPSKWVPAAQY  240
            +AG + VLSVGRVQTPTLA+VV RDREI  FVS P+  +   ++  G  F + W++A   
Sbjct  180  QAGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGC  239

Query  241  CDEEKRCIQSGVAAQVVQLCRQTPTAAIINCQIERKKQSAPLAFSLSTLQQACSRHWGMP  300
             D+  RC+Q + A Q  +  R + +A ++    ER ++++PL+F L+TLQ+ CSR+ ++ 
Sbjct  240  SDDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALD  299

Query  301  AQTVLDIAQKLYETHKLTTYPRTDCGYLPLSMREEIPQVLSAVVGTDPALQPVVASLDTQ  360
             Q  LDIAQ LYETHK TTYPR+D GYLP SM  E+P VL+A++ TDP+L+P++  LD  
Sbjct  300  VQETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRT  359

Query  361  FVSRIWNDKKITAHHGIIPTKHTGDLSKLSDAERNVYQLVRLHYLAQFLPQMEIDVTEAT  420
              SR WND K++AHHGIIPT + ++L+ +SD    VY+L+R HYLAQFLP+ E+D T A 
Sbjct  360  QRSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQ  419

Query  421  FNIGGQLFRTRGNVLVKPGWKSLFGKMSEDDEDNTG---ETTLPAMQAGQVCQVQGAEQK  477
            +  GGQ +++ G+ ++ PGW  +++    D+ D  +      LPA++ G  CQV+  + K
Sbjct  420  LLCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLSCQVNHVDLK  479

Query  478  VLQTKPPAPYNDGTLIAAMTNAAAFVTDAALKKVLKENAGIGTEATRAGIIDTLLKRGFL  537
             L+T+PP PY +G LI AM   A +VTD+ LK+ LKE +GIGTEATRA+II  LL RG+L
Sbjct  480  ALKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERGYL  539

Query  538  VREKKTLKSTPLGRNLVDVLPGTLTNPGLTALWEQMLDEVAAGRVSLDDFMAKQSQWVSQ  597
            ++  +T++++  +  L+D +P+++T+PG TA+WEQ LD + AG ++L+ F+AKQS W++Q
Sbjct  540  LKKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWITQ  599

Query  598  LVAQGRSQPLTMQAPPSPPCPVCGGKTLQRNGKSGLFWGCLKYPECKGIV  647
            LV Q R+  L+++ P +P+CP+CG+ T QR GK+G FW+C +YP+CKG +
Sbjct  600  LVQQYRAATLAIKLPEGPACPLCGSATRQRTGKTGPFWSCCRYPDCKGTL  649

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  566 bits (2136),  Expect = 1e-162, Method: Compositional matrix adjust.
 Identities = 330/650 (51%), Positives = 474/650 (73%), Gaps = 4/650 (0%)

Query  1    MRLVLCEKPSQGRDIAKFLGATQRGEGFLNGPGVTVTWARGHLLETAEPEVYGEQYGKPW  60
            MRL LCEKPSQG+DIA+ LGA QRG G  NG+G  VTW  GHL+E+A PE YGEQY K W
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQY-KRW  59

Query  61   RTDVLPLLPQQWKLVVKADAKAQFAVINRLLKQVDEVVIATDADREGEVIARELLDYCKF  120
              + LP++P++W++  KA + AQ+ ++++L+ Q  E+VIATDADREGE+IARE++D C +
Sbjct  60   SLEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGY  119

Query  121  QGRVFRLWMSALDDASIRSALADLWPSSRTESLYYAGVGRSRADWLIGMNLTRLFTLLGR  180
            +G + RLW+SAL+DASIR AL+ L PSS + +LY A+++RSRADWL+GMNL+RLFTLLGR
Sbjct  120  RGPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGR  179

Query  181  EAGIGNVLSVGRVQTPTLAIVVKRDREIDNFVSKPYFEVIATMAVNGVLFPSKWVPAAQY  240
            +AG + VLSVGRVQTPTLA+VV RDREI  FVS P+  +   ++  G  F + W++A   
Sbjct  180  QAGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGC  239

Query  241  CDEEKRCIQSGVAAQVVQLCRQTPTAAIINCQIERKKQSAPLAFSLSTLQQACSRHWGMP  300
             D+  RC+Q + A Q  +  R + +A ++    ER ++++PL+F L+TLQ+ CSR+ ++ 
Sbjct  240  SDDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALD  299

Query  301  AQTVLDIAQKLYETHKLTTYPRTDCGYLPLSMREEIPQVLSAVVGTDPALQPVVASLDTQ  360
             Q  LDIAQ LYETHK TTYPR+D GYLP SM  E+P VL+A++ TDP+L+P++  LD  
Sbjct  300  VQETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRT  359

Query  361  FVSRIWNDKKITAHHGIIPTKHTGDLSKLSDAERNVYQLVRLHYLAQFLPQMEIDVTEAT  420
              SR WND K++AHHGIIPT + ++L+ +SD    VY+L+R HYLAQFLP+ E+D T A 
Sbjct  360  QRSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQ  419

Query  421  FNIGGQLFRTRGNVLVKPGWKSLFGKMSEDDEDNTG---ETTLPAMQAGQVCQVQGAEQK  477
            +  GGQ +++ G+ ++ PGW  +++    D+ D  +      LPA++ G  CQV+  + K
Sbjct  420  LLCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLSCQVNHVDLK  479

Query  478  VLQTKPPAPYNDGTLIAAMTNAAAFVTDAALKKVLKENAGIGTEATRAGIIDTLLKRGFL  537
             L+T+PP PY +G LI AM   A +VTD+ LK+ LKE +GIGTEATRA+II  LL RG+L
Sbjct  480  ALKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERGYL  539

Query  538  VREKKTLKSTPLGRNLVDVLPGTLTNPGLTALWEQMLDEVAAGRVSLDDFMAKQSQWVSQ  597
            ++  +T++++  +  L+D +P+++T+PG TA+WEQ LD + AG ++L+ F+AKQS W++Q
Sbjct  540  LKKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWITQ  599

Query  598  LVAQGRSQPLTMQAPPSPPCPVCGGKTLQRNGKSGLFWGCLKYPECKGIV  647
            LV Q R+  L+++ P +P+CP+CG+ T QR GK+G FW+C +YP+CKG +
Sbjct  600  LVQQYRAATLAIKLPEGPACPLCGSATRQRTGKTGPFWSCCRYPDCKGTL  649

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  566 bits (2136),  Expect = 1e-162, Method: Compositional matrix adjust.
 Identities = 330/650 (51%), Positives = 474/650 (73%), Gaps = 4/650 (0%)

Query  1    MRLVLCEKPSQGRDIAKFLGATQRGEGFLNGPGVTVTWARGHLLETAEPEVYGEQYGKPW  60
            MRL LCEKPSQG+DIA+ LGA QRG G  NG+G  VTW  GHL+E+A PE YGEQY K W
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQY-KRW  59

Query  61   RTDVLPLLPQQWKLVVKADAKAQFAVINRLLKQVDEVVIATDADREGEVIARELLDYCKF  120
              + LP++P++W++  KA + AQ+ ++++L+ Q  E+VIATDADREGE+IARE++D C +
Sbjct  60   SLEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGY  119

Query  121  QGRVFRLWMSALDDASIRSALADLWPSSRTESLYYAGVGRSRADWLIGMNLTRLFTLLGR  180
            +G + RLW+SAL+DASIR AL+ L PSS + +LY A+++RSRADWL+GMNL+RLFTLLGR
Sbjct  120  RGPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGR  179

Query  181  EAGIGNVLSVGRVQTPTLAIVVKRDREIDNFVSKPYFEVIATMAVNGVLFPSKWVPAAQY  240
            +AG + VLSVGRVQTPTLA+VV RDREI  FVS P+  +   ++  G  F + W++A   
Sbjct  180  QAGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGC  239

Query  241  CDEEKRCIQSGVAAQVVQLCRQTPTAAIINCQIERKKQSAPLAFSLSTLQQACSRHWGMP  300
             D+  RC+Q + A Q  +  R + +A ++    ER ++++PL+F L+TLQ+ CSR+ ++ 
Sbjct  240  SDDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALD  299

Query  301  AQTVLDIAQKLYETHKLTTYPRTDCGYLPLSMREEIPQVLSAVVGTDPALQPVVASLDTQ  360
             Q  LDIAQ LYETHK TTYPR+D GYLP SM  E+P VL+A++ TDP+L+P++  LD  
Sbjct  300  VQETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRT  359

Query  361  FVSRIWNDKKITAHHGIIPTKHTGDLSKLSDAERNVYQLVRLHYLAQFLPQMEIDVTEAT  420
              SR WND K++AHHGIIPT + ++L+ +SD    VY+L+R HYLAQFLP+ E+D T A 
Sbjct  360  QRSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQ  419

Query  421  FNIGGQLFRTRGNVLVKPGWKSLFGKMSEDDEDNTG---ETTLPAMQAGQVCQVQGAEQK  477
            +  GGQ +++ G+ ++ PGW  +++    D+ D  +      LPA++ G  CQV+  + K
Sbjct  420  LLCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLSCQVNHVDLK  479

Query  478  VLQTKPPAPYNDGTLIAAMTNAAAFVTDAALKKVLKENAGIGTEATRAGIIDTLLKRGFL  537
             L+T+PP PY +G LI AM   A +VTD+ LK+ LKE +GIGTEATRA+II  LL RG+L
Sbjct  480  ALKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERGYL  539

Query  538  VREKKTLKSTPLGRNLVDVLPGTLTNPGLTALWEQMLDEVAAGRVSLDDFMAKQSQWVSQ  597
            ++  +T++++  +  L+D +P+++T+PG TA+WEQ LD + AG ++L+ F+AKQS W++Q
Sbjct  540  LKKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWITQ  599

Query  598  LVAQGRSQPLTMQAPPSPPCPVCGGKTLQRNGKSGLFWGCLKYPECKGIV  647
            LV Q R+  L+++ P +P+CP+CG+ T QR GK+G FW+C +YP+CKG +
Sbjct  600  LVQQYRAATLAIKLPEGPACPLCGSATRQRTGKTGPFWSCCRYPDCKGTL  649

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  566 bits (2136),  Expect = 1e-162, Method: Compositional matrix adjust.
 Identities = 330/650 (51%), Positives = 474/650 (73%), Gaps = 4/650 (0%)

Query  1    MRLVLCEKPSQGRDIAKFLGATQRGEGFLNGPGVTVTWARGHLLETAEPEVYGEQYGKPW  60
            MRL LCEKPSQG+DIA+ LGA QRG G  NG+G  VTW  GHL+E+A PE YGEQY K W
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQY-KRW  59

Query  61   RTDVLPLLPQQWKLVVKADAKAQFAVINRLLKQVDEVVIATDADREGEVIARELLDYCKF  120
              + LP++P++W++  KA + AQ+ ++++L+ Q  E+VIATDADREGE+IARE++D C +
Sbjct  60   SLEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGY  119

Query  121  QGRVFRLWMSALDDASIRSALADLWPSSRTESLYYAGVGRSRADWLIGMNLTRLFTLLGR  180
            +G + RLW+SAL+DASIR AL+ L PSS + +LY A+++RSRADWL+GMNL+RLFTLLGR
Sbjct  120  RGPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGR  179

Query  181  EAGIGNVLSVGRVQTPTLAIVVKRDREIDNFVSKPYFEVIATMAVNGVLFPSKWVPAAQY  240
            +AG + VLSVGRVQTPTLA+VV RDREI  FVS P+  +   ++  G  F + W++A   
Sbjct  180  QAGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGC  239

Query  241  CDEEKRCIQSGVAAQVVQLCRQTPTAAIINCQIERKKQSAPLAFSLSTLQQACSRHWGMP  300
             D+  RC+Q + A Q  +  R + +A ++    ER ++++PL+F L+TLQ+ CSR+ ++ 
Sbjct  240  SDDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALD  299

Query  301  AQTVLDIAQKLYETHKLTTYPRTDCGYLPLSMREEIPQVLSAVVGTDPALQPVVASLDTQ  360
             Q  LDIAQ LYETHK TTYPR+D GYLP SM  E+P VL+A++ TDP+L+P++  LD  
Sbjct  300  VQETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRT  359

Query  361  FVSRIWNDKKITAHHGIIPTKHTGDLSKLSDAERNVYQLVRLHYLAQFLPQMEIDVTEAT  420
              SR WND K++AHHGIIPT + ++L+ +SD    VY+L+R HYLAQFLP+ E+D T A 
Sbjct  360  QRSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQ  419

Query  421  FNIGGQLFRTRGNVLVKPGWKSLFGKMSEDDEDNTG---ETTLPAMQAGQVCQVQGAEQK  477
            +  GGQ +++ G+ ++ PGW  +++    D+ D  +      LPA++ G  CQV+  + K
Sbjct  420  LLCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLSCQVNHVDLK  479

Query  478  VLQTKPPAPYNDGTLIAAMTNAAAFVTDAALKKVLKENAGIGTEATRAGIIDTLLKRGFL  537
             L+T+PP PY +G LI AM   A +VTD+ LK+ LKE +GIGTEATRA+II  LL RG+L
Sbjct  480  ALKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERGYL  539

Query  538  VREKKTLKSTPLGRNLVDVLPGTLTNPGLTALWEQMLDEVAAGRVSLDDFMAKQSQWVSQ  597
            ++  +T++++  +  L+D +P+++T+PG TA+WEQ LD + AG ++L+ F+AKQS W++Q
Sbjct  540  LKKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWITQ  599

Query  598  LVAQGRSQPLTMQAPPSPPCPVCGGKTLQRNGKSGLFWGCLKYPECKGIV  647
            LV Q R+  L+++ P +P+CP+CG+ T QR GK+G FW+C +YP+CKG +
Sbjct  600  LVQQYRAATLAIKLPEGPACPLCGSATRQRTGKTGPFWSCCRYPDCKGTL  649

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  565 bits (2132),  Expect = 3e-162, Method: Compositional matrix adjust.
 Identities = 329/650 (51%), Positives = 473/650 (73%), Gaps = 4/650 (0%)

Query  1    MRLVLCEKPSQGRDIAKFLGATQRGEGFLNGPGVTVTWARGHLLETAEPEVYGEQYGKPW  60
            MRL LCEKPSQG+DIA+ LGA QRG G  NG+G  VTW  GHL+E+A PE YGEQY K W
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQY-KRW  59

Query  61   RTDVLPLLPQQWKLVVKADAKAQFAVINRLLKQVDEVVIATDADREGEVIARELLDYCKF  120
              + LP++P++W++  KA + AQ+ ++++L+ Q  E+VIATDADREGE+IARE++D C +
Sbjct  60   SLEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGY  119

Query  121  QGRVFRLWMSALDDASIRSALADLWPSSRTESLYYAGVGRSRADWLIGMNLTRLFTLLGR  180
            +G + RLW+SAL+DASIR AL+ L PSS + +LY A+++RSRADWL+GMNL+RLFTLLGR
Sbjct  120  RGPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGR  179

Query  181  EAGIGNVLSVGRVQTPTLAIVVKRDREIDNFVSKPYFEVIATMAVNGVLFPSKWVPAAQY  240
            +AG + VLSVGRVQTPTLA+VV RDREI  FVS P+  +   ++  G  F + W++A   
Sbjct  180  QAGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGC  239

Query  241  CDEEKRCIQSGVAAQVVQLCRQTPTAAIINCQIERKKQSAPLAFSLSTLQQACSRHWGMP  300
             D+  RC+Q + A Q  +  R + +A ++    ER ++++PL+F L+TLQ+ CSR+ ++ 
Sbjct  240  SDDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALD  299

Query  301  AQTVLDIAQKLYETHKLTTYPRTDCGYLPLSMREEIPQVLSAVVGTDPALQPVVASLDTQ  360
             Q  LDIAQ LYETHK TTYPR+D GYLP SM  E+P VL+A++ TDP+L+P++  LD  
Sbjct  300  VQETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRT  359

Query  361  FVSRIWNDKKITAHHGIIPTKHTGDLSKLSDAERNVYQLVRLHYLAQFLPQMEIDVTEVT  420
              SR WND K++AHHGIIPT + ++L+ +SD    VY+L+R HYLAQFLP+ E+D T   
Sbjct  360  QRSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQ  419

Query  421  FNIGGQLFRTRGNVLVKPGWKSLFGKMSEDDEDNTG---ETTLPAMQAGQVCQVQGAEQK  477
            +  GGQ +++ G+ ++ PGW  +++    D+ D  +      LPA++ G  CQV+  + K
Sbjct  420  LLCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLSCQVNHVDLK  479

Query  478  VLQTKPPAPYNDGTLIAAMTNAAAFVTDAALKKVLKENAGIGTEATRAGIIDTLLKRGFL  537
             L+T+PP PY +G LI AM   A +VTD+ LK+ LKE +GIGTEATRA+II  LL RG+L
Sbjct  480  ALKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERGYL  539

Query  538  VREKKTLKSTPLGRNLVDVLPGTLTNPGLTALWEQMLDEVAAGRVSLDDFMAKQSQWVSQ  597
            ++  +T++++  +  L+D +P+++T+PG TA+WEQ LD + AG ++L+ F+AKQS W++Q
Sbjct  540  LKKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWITQ  599

Query  598  LVAQGRSQPLTMQAPPSPPCPVCGGKTLQRNGKSGLFWGCLKYPECKGIV  647
            LV Q R+  L+++ P +P+CP+CG+ T QR GK+G FW+C +YP+CKG +
Sbjct  600  LVQQYRAATLAIKLPEGPACPLCGSATRQRTGKTGPFWSCCRYPDCKGTL  649

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  564 bits (2130),  Expect = 4e-162, Method: Compositional matrix adjust.
 Identities = 330/668 (50%), Positives = 481/668 (73%), Gaps = 1/668 (0%)

Query  1    MRLFICEKPSQARDIAAVLGATKRGQGFLSAPGITITWARGHLLETASPEVYGTQFEKPW  60
            MRLF+CEKPSQ++DIA VLGA +RG G  +++G  +TW  GHL+E+A+PE YG Q+ K W
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQY-KRW  59

Query  61   RIDVLPVLPPVWQMVVKSESSDQFTVISRLLKQVDEVVISTDADREGEVIGWSLLEYCGW  120
             ++ LP++P  W++  K+ ++ Q+ ++ +L+ Q  E+VI+TDADREGE+I++ +++ CG 
Sbjct  60   SLEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGY  119

Query  121  RGPVFRLWLSALDESSIRAALAAIKPGSETKPLYYAGLGRSRADWLIGMNLTRLYTVKAR  180
            RGP+ RLWLSAL+++SIR AL+A+KP+SE+ PLY A+L+RSRADWL+GMNL+RL+T+ +R
Sbjct  120  RGPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGR  179

Query  181  DKGYDGLLSVGRVQTPVLAMVVNREREIATFVPKPYWQVWVALQSNGVRFSAQWVPAKMY  240
            + GYDG+LSVGRVQTP LA+VV R+REIA FV+ P+W + V+L + G  F A W++A   
Sbjct  180  QAGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGC  239

Query  241  VDEEKRCIHQDIAQQVAQLCKQTGKATVIEQETKREKEAAPLAFTMGTLQQACGRLWDMS  300
             D+  RC++Q  AQQ A+  + +G A V+   T R +EA+PL+F +GTLQ+ C+R   + 
Sbjct  240  SDDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALD  299

Query  301  PQKVLDIAQSLYETHKATSYPRTDCGFLPESMREEIPDVLSALVKIDPSLQALISQLDTR  360
             Q  LDIAQ+LYETHKAT+YPR+D G+LPESM  E+P VL+A++  DPSL++L+ QLD  
Sbjct  300  VQETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRT  359

Query  361  FVSRIWDDKKMTAHHGIIPTRHVCDMSKMSDQEKQVYVLIRRHYLAQFFPLHEVDFTRLS  420
              SR W+D K++AHHGIIPT +  +++ +SD+   VY LIR HYLAQF+P  E D T   
Sbjct  360  QRSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQ  419

Query  421  LNIGGQLFQTTGRVVVVPGWKRLFSQDDGEHKEAAADEKDQSLPMLVKGDNCGVAGSEVK  480
            L  GGQ +Q+ G+ V++PGW ++++  ++++ ++ A  + Q LP L  G +C V   ++K
Sbjct  420  LLCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLSCQVNHVDLK  479

Query  481  ALKTKPPQYFTFQSLIAAMMNAAAYVTDLTLKKVLKENAGLGTEATRGGIVETLLARNFI  540
            ALKT+PP+ +T   LI AM   A  VTD  LK+ LKE +G+GTEATR++I+  LL R ++
Sbjct  480  ALKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERGYL  539

Query  541  SIKGRYLRATDIAMDLIDALPHALKEPGMTALWEQALDEVAKGRMTLDSFMSRQTQWICQ  600
              KGR +RA+D A  LIDA+P A+ +PG TA+WEQALD +  G MTL++F+++Q+ WI Q
Sbjct  540  LKKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWITQ  599

Query  601  LVSLGTQQDVVVRVPPTPACPLCGSKTRLRKGAKGAFYGCEKYPDCKGMINVPGQSKNAA  660
            LV       + +++P  PACPLCGS TR R G  G+F +C +YPDCKG + V    + +A
Sbjct  600  LVQQYRAATLAIKLPEGPACPLCGSATRQRTGKTGPFWSCCRYPDCKGTLPVQNGRQASA  659

Query  661  SKTRKKKQ  668
             ++  +K 
Sbjct  660  KRSTSRKP  667

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  562 bits (2123),  Expect = 2e-161, Method: Compositional matrix adjust.
 Identities = 329/650 (51%), Positives = 474/650 (73%), Gaps = 4/650 (0%)

Query  1    MQLYLCEKPSQAKDIARVLGISKRGQGFISADNITVTWAIGHLLEQASPDAYGEQFGKPW  60
            M+L+LCEKPSQ+KDIARVLG ++RG G  ++    VTW IGHL+E A+P+AYGEQ+ K W
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQY-KRW  59

Query  61   RVDVLPVLPDNWKMVVKPQTRDQFTVISKLLKQAGEVIIATDADREGEVIARELLAYCGY  120
             ++ LP++P+ W++  K+ T  Q+ ++ +L+ QA+E++IATDADREGE+IARE++  CGY
Sbjct  60   SLEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGY  119

Query  121  RGAVRRLWLSALDEASIREALAGILPGENTAKLYDAGLGRSRADWLIGMNLTRLYTLIAR  180
            RG+++RLWLSAL++ASIR AL+++ P+ ++  LY A+L+RSRADWL+GMNL+RL+TL++R
Sbjct  120  RGPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGR  179

Query  181  ESGVSDVLSVGRVQTPTLAIVVNRDKEIADFVPVPWWQVQVLLEKDGVRFRATWQAAAQY  240
            ++G  +VLSVGRVQTPTLA+VV RD+EIA FV+VP W ++V L  +G  F ATW AA   
Sbjct  180  QAGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGC  239

Query  241  CDDEKRCVNKQAANAVGQLCQQQKGATVLEVSQKRDKTPAPLCFDLGTLQLVCSRKFGMG  300
             DD  RC+++ +A+  ++  +   +A V+ V+  R + ++PL FDLGTLQ VCSR+++++
Sbjct  240  SDDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALD  299

Query  301  AKETLAVAQSLYETHKATTYPRTDCGYLPTSMQKEIPEVMGSVAKSDPSVAPVLAQLDRG  360
             +ETL +AQ+LYETHKATTYPR+D GYLP SM  E+P V++++  +DPS+ P+L QLDR 
Sbjct  300  VQETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRT  359

Query  361  FVSRVWNDKKITAHHAIIPTRQAFDLSRLSADELKVYQLIRQHYFAQFLPLQESDVTDAS  420
              SR WND K++AHH+IIPT ++ +L+ +S   L VY+LIR HY+AQFLP  E D T A 
Sbjct  360  QRSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQ  419

Query  421  FNIGGQLFLAKGKVNVITGWTCLFQKEIQEDPPEDD---DMALPALNKGDSCIVNGASVG  477
            +  GGQ + A GK  +I GW  ++     +++  +       LPAL  G SC VN   + 
Sbjct  420  LLCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLSCQVNHVDLK  479

Query  478  DKVTSPPKPFTEGTLIAAMKNAASFVSDPKLKKVLRDNAGLGTEATRAGVLETLFSRHYL  537
               T PPKP+T+G LI AMK  A +V+DP+LK+ L++ +G+GTEATRA+++  L+ R YL
Sbjct  480  ALKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERGYL  539

Query  538  EKKGKHIHATLLARELIAALPETLTSPGMTALWEQALDDIAQGKMSLDTFIQKQLQWTRH  597
             KKG+ ++A+  A  LI A+P ++T PG TA+WEQALD I  G M+L+TF+ KQ  W  +
Sbjct  540  LKKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWITQ  599

Query  598  LVDKGRADTVKITAPVTPPCPVCKGLTRKRKGKNGDFWGCIRYPECNGIV  647
            LV++ RA T+ I  P  P+CP+C + TR+R GK G FW+C RYP+C+G +
Sbjct  600  LVQQYRAATLAIKLPEGPACPLCGSATRQRTGKTGPFWSCCRYPDCKGTL  649

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  560 bits (2116),  Expect = 6e-161, Method: Compositional matrix adjust.
 Identities = 327/650 (51%), Positives = 471/650 (73%), Gaps = 2/650 (0%)

Query  1    MQLYLCEKPSQAKDIARVLGVSQRGQGCINGGNITVTWAVGHLLETATPEIYGEQFGRPW  60
            M+L+LCEKPSQ+KDIARVLG +QRG GC NG+   VTW +GHL+E+A PE YGEQ+ R W
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQYKR-W  59

Query  61   RAEVLPIIPDRWQMTVKKDTADQFAVIKKLLKQASEVVIATDADREGEVIARELMEYCNY  120
              E LPIIP+RW++  K  TA Q+ ++K+L+ QASE+VIATDADREGE+IARE+++ C Y
Sbjct  60   SLEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGY  119

Query  121  RGAVRRLWLSALDEASIKKALGEMLPGDKTEMLYQAGVGRSRADWLIGMNLTRLYTLKAG  180
            RG+++RLWLSAL++ASI+KALG + P+  +  LY A+++RSRADWL+GMNL+RL+TL + 
Sbjct  120  RGPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGR  179

Query  181  EAGVSEVFSVGRVQTPTLAIVVNRDLEIAGFTPKPWWKVRAQLQKDDVSFEAEWVAAAQY  240
            +AG   V+SVGRVQTPTLA+VV RD EIA F + P W +   L  ++ SF A W+AA   
Sbjct  180  QAGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGC  239

Query  241  CDDEKRCVNHPIAQAVQQLCQKAGSGSVISVEKKRDKTPAPLCFTLGTLMEVCNKKWGFG  300
             DD  RC++++ AQ   +  + AGS+ V++V   R + ++PL F LGTL +VC+++ +++
Sbjct  240  SDDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALD  299

Query  301  ANEVLSIAQSLYETHKATTYPRTDCGYLPVSMREEVRDVLQAIQHSDPSITPELARLDTA  360
             +E L IAQ+LYETHKATTYPR+D GYLP SM  EV  VL A+  +DPS+ P L +LD +
Sbjct  300  VQETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRT  359

Query  361  FTSRVWNDKKITAHHAIIPTRQPFEIAKLNAKELKVYSLIRLHYLAQFMPLQESDVTDAT  420
              SR WND K++AHH+IIPT +P ++A ++ K L VY LIR HYLAQF+P  E D T A 
Sbjct  360  QRSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQ  419

Query  421  FNIGNQLFRTRGRVMIHAGWKSLFSGQLSEEGEEDKESAAQ-LPALEQGSVCSVTGADVK  479
            +  G Q +++ G+ +I +GW  +++G  +++++ +  + +Q LPAL +G  C V   D+K
Sbjct  420  LLCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLSCQVNHVDLK  479

Query  480  DNMTKAPPHHTEGTLIAAMKNAASLVTDPQLKKVLRDNAGLGTEATRSGVLETLFKRGFL  539
               T++P   T+G LI AMK  A LVTDP+LK+ L++ +G+GTEATR++++  L+ RG+L
Sbjct  480  ALKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERGYL  539

Query  540  EKKGKFIQATQMARELIAALPETLTSPGMTALWEQALDDIAQGKSGLSDFMQKQTQWTRH  599
             KKG+ ++A++ A  LI A+P ++T PG TA+WEQALD I  G   L  F+ KQ+ W  +
Sbjct  540  LKKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWITQ  599

Query  600  LIEKGRVAAFKITVPVGPSCPKCGGPTQQRKNKEDKFWGCMKFPDCKGIV  649
            L+++ R A++ I +P GP+CP CG++T+QR  K + FW+C ++PDCKG +
Sbjct  600  LVQQYRAATLAIKLPEGPACPLCGSATRQRTGKTGPFWSCCRYPDCKGTL  649

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  560 bits (2114),  Expect = 8e-161, Method: Compositional matrix adjust.
 Identities = 326/668 (49%), Positives = 481/668 (73%), Gaps = 2/668 (0%)

Query  1    MRLFICEKPSQARDIAAVIGATKRGQGFLSAPGITITWARGHLLETASPEVYGTQFEKPW  60
            MRLF+CEKPSQ++DIA V+GA +RG G  +++G  +TW  GHL+E+A+PE YG Q+ K W
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQY-KRW  59

Query  61   RIDVLPVLPPVWQMVVKPESLDQFTVISRLLKQVDEVVISTDADREGEVIGWSLLEYCGW  120
             ++ LP++P  W++  K+ +  Q+ ++ +L+ Q  E+VI+TDADREGE+I++ +++ CG 
Sbjct  60   SLEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGY  119

Query  121  RGPVFRLWLSALDESSIRTALAAIKPGAETKPLYYAGLGRSRADWLIGMNLTRLYTVKAR  180
            RGP+ RLWLSAL+++SIR AL+A+KP++E+ PLY A+L+RSRADWL+GMNL+RL+T+ +R
Sbjct  120  RGPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGR  179

Query  181  DKGYDGLLSVGRVQTPVLAMVVNREREIAAFVPKPYWQVWVALQSNGVRFSAQWVPAKMY  240
            + GYDG+LSVGRVQTP LA+VV R+REIA FV+ P+W + V+L + G  F A W++A   
Sbjct  180  QAGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGC  239

Query  241  VDEEKRCIHQGIAQQVAQLCKQTGKATVIEQETKREKEAAPLAFTMGTLQQACGRLWDMS  300
             D+  RC++Q+ AQQ A+  + +G A V+   T R +EA+PL+F +GTLQ+ C+R   + 
Sbjct  240  SDDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALD  299

Query  301  PQKVLDIAQSLYETHKATSYPRTDCGFLPESMREEIPDVLSALVKIDPSLQELIPQLDTR  360
             Q  LDIAQ+LYETHKAT+YPR+D G+LPESM  E+P VL+A++  DPSL+ L+ QLD  
Sbjct  300  VQETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRT  359

Query  361  FVSRIWDDKNITAHHGIIPTRHVSDMSKMSEQEKQVYLLIRRHYLAQFLPLHEVDATRLS  420
              SR W+D +++AHHGIIPT + ++++ +S++   VY LIR HYLAQFLP  E D T   
Sbjct  360  QRSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQ  419

Query  421  LNIGGQLFQTTGRVVVVPGWKRLFSQQDDGEHKESAADEKDQSLPMLVKGDNCAVTGAEV  480
            L  GGQ +Q+ G+ V++PGW ++++   ++++ ++ A  + Q LP L  G +C V   ++
Sbjct  420  LLCGGQTLQAVGKQVIIPGWHQVLAGP-EADNADGEAVPRSQVLPALREGLSCQVNHVDL  478

Query  481  KALKTKPPQYFTFQSLIAAMMNAAAYVTDLTLKKVLKENAGLGTEATRGGIVETLLARNF  540
            KALKT+PP+ +T   LI AM   A  VTD  LK+ LKE +G+GTEATR++I+  LL R +
Sbjct  479  KALKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERGY  538

Query  541  IIIKGRYLRATDIAMDLIDALPHALKEPGMTALWEQALDEVAKGKMTLDNFMSRQTQWIC  600
            ++ KGR +RA+D A  LIDA+P A+ +PG TA+WEQALD +  G MTL+ F+++Q+ WI 
Sbjct  539  LLKKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWIT  598

Query  601  QLVSLGAQQDVVVRVPPTPACPLCGSKTRLRKGVKGSFYGCEKYPDCKGMINIPGQGKNT  660
            QLV       + +++P  PACPLCGS TR R G  G+F +C +YPDCKG + +    + +
Sbjct  599  QLVQQYRAATLAIKLPEGPACPLCGSATRQRTGKTGPFWSCCRYPDCKGTLPVQNGRQAS  658

Query  661  APKTRKKK  668
            A ++  +K
Sbjct  659  AKRSTSRK  666

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  559 bits (2112),  Expect = 1e-160, Method: Compositional matrix adjust.
 Identities = 338/656 (52%), Positives = 479/656 (74%), Gaps = 5/656 (0%)

Query  1    MQLYLCEKPSQGKDIGAILGATQRKQGYLAGAGVIVTWAIGHLLEQAQPETYGEQFGSPW  60
            M+L+LCEKPSQGKDI+ +LGA QR  G   GAG +VTW IGHL+E A PE+YGEQ+   W
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQY-KRW  59

Query  61   RESVLPIVPTQWKMTVKKETADQFAVIRGLLKQVDSVVIATDADREGEVIARELLEHCHF  120
                LPI+P +W++  K  TA Q+ +++ L+ Q   +VIATDADREGE+IARE+++ C +
Sbjct  60   SLEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGY  119

Query  121  TGPVQRLWLSALDEASIRHALANKLPGEKTAPLYEAGLARSRADWMTGMNLTRLYTLKAR  180
             GP+QRLWLSAL++ASIR AL+   P+  + PLY A+LARSRADW+ GMNL+RL+TL +R
Sbjct  120  RGPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGR  179

Query  181  EQGYGEVLSIGRVQTPTLALVVNRDRDIANFISKPYWQVRATLQKGGIAFPASWVPAANY  240
            + GY+ VLS+GRVQTPTLALVV RDR+IA F+S P+W +   L  GG +F A+W++A   
Sbjct  180  QAGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGC  239

Query  241  CDEEKRCIQQNVAQAVVQLCQQTGHAVVLEVGTERKKESAPLAFDLGTLQQACSRKWGMS  300
             D+  RC+QQ  AQ   +  + +G A V+ V TER +E++PL+FDLGTLQ+ CSR+ ++ 
Sbjct  240  SDDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALD  299

Query  301  ANQALSIAQSLYETHKATTYPRTDCGYLPTSMREEVADVLSAVTRTDPTQSGSVARLDRT  360
             +++L IAQ+LYETHKATTYPR+D GYLP SM  EV+ VL+A+  TDP+    + +LDRT
Sbjct  300  VQETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRT  359

Query  361  FVSRIWNDKKITAHHGIIPTKQPFDLSKLSADELKVYQLIRQHYLAQFLPLHEVDVTEAT  420
              SR WND K++AHHGIIPT +P +L+ +S   L VY+LIR HYLAQFLP  E D T A 
Sbjct  360  QRSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQ  419

Query  421  FNIGGQLFRTRGKVEVVAGW-KVLFQHDVSEAKEESTDTDDVRLPALVKGETVAVAGAEL  479
            +  GGQ +++ GK  +++GW +VL   +  +A  E+    +V LPAL  G +  V   +L
Sbjct  420  LLCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQV-LPALREGLSCQVNHVDL  478

Query  480  KTLQTKPPGHFTDGTLIAAMKNAAAFVSDPQLKKVLKENAGLGTEATRAGILETLFKRGY  539
            K+L+T+PP  +T+G LI AMK  A +V+DP+LK+ LKE +G+GTEATRA+I+  L+ RGY
Sbjct  479  KALKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERGY  538

Query  540  LEKKGKYLLSTPIAGELIDALPTALTNPGMTALWEQALDEIAQGQMTLDTFMSRQAQWTG  599
            L KKG+ + ++  AG LIDA+P+A+T+PG TA+WEQALD I  G+MTL+TF+++Q+ W  
Sbjct  539  LLKKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWIT  598

Query  600  HLVEKGKAQAVKFtappsppcptcsGTMRRRAGKKGSGAFWGCSNYPTCQGIINID  655
            +LV++ +A ++ +  P +P+CP C+++ R+R+GK  +G+FW+C  YP C+G + ++
Sbjct  599  QLVQQYRAATLAIKLPEGPACPLCGSATRQRTGK--TGPFWSCCRYPDCKGTLPVQ  652

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  559 bits (2111),  Expect = 1e-160, Method: Compositional matrix adjust.
 Identities = 337/670 (51%), Positives = 486/670 (73%), Gaps = 3/670 (0%)

Query  1    MRLFICEKPSQGRDLANVLGATRRGDGFLTGPGVTVTWAVGHLLETAPPEAYGQQYGKPW  60
            MRLF+CEKPSQG+D+A VLGA +RG G   G+G  VTW +GHL+E+APPEAYG+QY K W
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQY-KRW  59

Query  61   SLSALPILPSPWQVVVKKETKSQFKVIERLLRQVDDVVISTDADREGEVIARELLEYCRW  120
            SL  LPI+P  W+V  K  T +Q+K++ +L+ Q  ++VI+TDADREGE+IARE+++ C  
Sbjct  60   SLEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGY  119

Query  121  DGPVQRLWLSALDEMSIRAALQDLRPGAETLGMYHAGLGRARADWLIGMNLSRLYTLLAV  180
             GP+QRLWLSAL++ SIR AL  L+P++E+L +Y A+L+R+RADWL+GMNLSRL+TLL+ 
Sbjct  120  RGPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGR  179

Query  181  QSGFDGVISVGRVQTPTLALVVRRDREIATFVPKPFWQVKALLSAGGRTFPAQWVPAKVY  240
            Q+G+DGV+SVGRVQTPTLALVV RDREIA FV+ PFW +   LS+GG++F A W++A   
Sbjct  180  QAGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGC  239

Query  241  TDEEKRCVHQNIAQQVAHLCRQAGAATVTECETKREKAAAPLAFSLGTLQQACGLLWDMS  300
            +D+  RC++Q  AQQ A+  R AG+A V    T R + A+PL+F LGTLQ+ C+    + 
Sbjct  240  SDDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALD  299

Query  301  PQQVLDTAQSLYEKHKATTYPRTDCGYLPESMREEIPSVLSAIGLSDPECSSLLSGLNTS  360
             Q+ LD AQ+LYE HKATTYPR+D GYLPESM  E+P+VL+A+  +DP   +LL  L+ +
Sbjct  300  VQETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRT  359

Query  361  FVSRIWNDKKITAHHGIIPTRNAFKFSALSEAERRVYTLIRRNYLAQFLPLHESDITRLQ  420
              SR WND K++AHHGIIPT ++ +++A+S+    VY LIR +YLAQFLP  E D T  Q
Sbjct  360  QRSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQ  419

Query  421  FDIGGQLFRTTGRTEIVMGWKVLFSKEEEDSAGDDDLSIE--LPPLRQGDRCGVNGAEVV  478
            +  GGQ +++ G+  I+ GW  +++  E D+A+++ ++    LP+LR+G  C VN  ++ 
Sbjct  420  LLCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLSCQVNHVDLK  479

Query  479  QQMTRPPAHYTFATLIGAMMNASAFVTDIALRKVLKDNAGLGTEATRAGIVEQLLNRRFI  538
               T+PP  YT + LI AM   + +VTD  L++ LK+ +G+GTEATRA+I+  LL+R ++
Sbjct  480  ALKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERGYL  539

Query  539  VRKGKQLRATDLGADVIDALPSQLTDPGMTALWEQALDEVAEGRLTLNDFLQRQVGWTRN  598
            ++KG+ +RA+D ++ +IDA+P+ +TDPG TA+WEQALD +  G +TL+ F+ +Q  W  +
Sbjct  540  LKKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWITQ  599

Query  599  LVSMGGQQRVSIRIPPTPSCPLCGGKTRLKKGQKGEFWGCTRYPDCKGIINNDTQkrksa  658
            LV       ++I++P  P+CPLCG+ TR + G+ G FW+C RYPDCKG +  +  ++ SA
Sbjct  600  LVQQYRAATLAIKLPEGPACPLCGSATRQRTGKTGPFWSCCRYPDCKGTLPVQNGRQASA  659

Query  659  rsskaVKPKN  668
            + S + KP++
Sbjct  660  KRSTSRKPRQ  669

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  558 bits (2107),  Expect = 3e-160, Method: Compositional matrix adjust.
 Identities = 330/672 (50%), Positives = 478/672 (72%), Gaps = 6/672 (0%)

Query  1    MKLFLCEKPSQAKDIARVIGAHQRRDNFFQGNGVQVAWARGHLLEQAEPEAYGAQFAAPW  60
            M+LFLCEKPSQ+KDIARV+GA QR    ++G G  V+W  GHL+E A PEAYG Q+   W
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQYK-RW  59

Query  61   RQSALPVIPEQWKMVVKKDAVSLFQTIKQLLSQATEVVIATDADREGEVIARELLEACHY  120
                LP+IPE+W++  K  + + ++ +KQL++QA+E+VIATDADREGE+IARE+++ C Y
Sbjct  60   SLEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGY  119

Query  121  RKKVQRLWLSALDEASIRQALNNLLPGEKTASLYSAGLGRARADWLIGMNMTRLFTLKAR  180
            R  +QRLWLSAL++ASIR+AL  L P+  + +LY+A+L+R+RADWL+GMN++RLFTL +R
Sbjct  120  RGPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGR  179

Query  181  ELGFGGILSVGRVQTPTLALIVRREREITHFVSKPFWRVTASLQHQGIIFQAHWRPASQY  240
            + G++G+LSVGRVQTPTLAL+V R+REI++FVS PFW +  +L   G  F A W +A   
Sbjct  180  QAGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGC  239

Query  241  CDDEHRCIHVQAAQAVEQLCRQAGKATVCTVNETKGKALPPLPFDLGTLQQAASRRWGYS  300
             DD  RC++  +AQ   +  R AG A V +V   + +  PPLPFDLGTLQ+  SR+ +  
Sbjct  240  SDDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALD  299

Query  301  ADKVLEIAQSLYEKHKATTYPRTDCGYLPVSMRADIPVVLDALSQSDPALQNVLAQLQPA  360
             +  L+IAQ+LYE HKATTYPR+D GYLP SM A++P VL A+  +DP+L+ +L QL+ +
Sbjct  300  VQETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRT  359

Query  361  RISRVWNDAKITAHHAIIPTRQTPDLNAMNEAELNVYKLIRAHYLAQFLPDQEWDATEVF  420
            + SR WND+K++AHH+IIPT + ++L A+++  L VY+LIRAHYLAQFLP+ E D T   
Sbjct  360  QRSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQ  419

Query  421  LDIGGQQFVAKGKVERVKGWSVLFVKHEDDPPVKeeaetgleagtetlPSLHEGEFCVVQ  480
            L  GGQ + A GK   + GW  ++   E D +     +    + ++ LP+L+EG  C V+
Sbjct  420  LLCGGQTLQAVGKQVIIPGWHQVLAGPEADNA-----DGEAVPRSQVLPALREGLSCQVN  474

Query  481  EAKVVQLATSPPKPYTDGTLIAAMKNASSFITDPTLKKVLKENAGLGTEATRAGIITTLE  540
            +  +  L T PPKPYT+G LI AMK  + ++TDP LK+ LKE +G+GTEATRA+II  L 
Sbjct  475  HVDLKALKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLL  534

Query  541  NRKLIVRQKKTLRATDTGCQLIDALPAACTDPGMTALWEQSLEQVAQGNLSLDVFMQKQI  600
            +R  ++++ +T+RA+D++ +LIDA+PAA TDPG TA+WEQ+L+ +  G+++L+ F+ KQ 
Sbjct  535  ERGYLLKKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQS  594

Query  601  SWLAHLIKKGGEMPLALDLPPMPSCPSCHGKMVLRESSKGRFWSCQRYPDCKGSVPLPEK  660
            +W+++L+++     LA+ LP  P+CP C +    R +  G FWSC RYPDCKG++P+ + 
Sbjct  595  TWITQLVQQYRAATLAIKLPEGPACPLCGSATRQRTGKTGPFWSCCRYPDCKGTLPVQNG  654

Query  661  MQGVTRGMNKRK  672
             Q+ ++    RK
Sbjct  655  RQASAKRSTSRK  666

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  555 bits (2095),  Expect = 3e-159, Method: Compositional matrix adjust.
 Identities = 334/654 (52%), Positives = 476/654 (73%), Gaps = 2/654 (0%)

Query  1    MQLYLCEKPSQARDIARVLGLSGRGEGCIEGDTVTVTWAVGHLLELAAPEAYGEQFGVPW  60
            M+L+LCEKPSQ++DIARVLG + RG GC +G    VTW +GHL+E A+PEAYGEQ+   W
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQYK-RW  59

Query  61   RMESLPVLPEKWQMTVKPQTKSQFTVISRLLKRASEVVIATDADREGEVIARELLTYCRY  120
             +E LP++PE+W++  K+ T +Q+ ++ +L+ +ASE+VIATDADREGE+IARE++  C Y
Sbjct  60   SLEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGY  119

Query  121  RGPVRRLWLSALDEASVREALANILPGEQTARLYDAGLARGQADWLIGMNLTRLYTLKAR  180
            RGP++RLWLSAL++AS+R AL+ + P+ ++  LY A+LAR++ADWL+GMNL+RL+TL +R
Sbjct  120  RGPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGR  179

Query  181  VSGIPDVLSVGRVQTPTLAMVVRRDQEIAGFVPRPWWQVFVGLEKDGIRFRAVWVAAEQY  240
             +G  +VLSVGRVQTPTLA+VV RD+EIA FV+ P W + VGL  +G  F A W+AA+  
Sbjct  180  QAGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGC  239

Query  241  CDEEKRCVNVQAARAVLQLCQQTPSAVVHEVTRKREKTPAPLCFSLGTLQEACSRKFGMG  300
             D+  RC++  +A+   +  + + SA V  VT  R + ++PL F LGTLQ+ CSR+++++
Sbjct  240  SDDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALD  299

Query  301  AQTVLNIAQSLYETHKATTYPRTDCGYLPESMQQESREVLAAMARSDPALTPVLAQLDPG  360
             Q  L+IAQ+LYETHKATTYPR+D GYLPESM  E   VLAAM  +DP+L P+L QLD  
Sbjct  300  VQETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRT  359

Query  361  FVSRIWNDKKITAHHAIIPTRQVFDIRALSEDELKVYLLIRQHYLAQFLPLQESDITDAT  420
              SR WND K++AHH+IIPT +  ++ A+S+  L VY LIR HYLAQFLP  E D T A 
Sbjct  360  QRSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQ  419

Query  421  LTLGGQRFRARGKVNVVTGWRGLFSgeaaedaegedeQTTEMALPALERGEHCRISGSEL  480
            L  GGQ ++A GK  ++ GW+ +++G  A++A+GE    +++ LPAL  G  C+++  +L
Sbjct  420  LLCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQV-LPALREGLSCQVNHVDL  478

Query  481  KGRMTSPPAPFTEGTLIAAMKNAASQVSDPKLKKVLRENAGLGTEATRAGVLEVLFARQY  540
            K+  T PP P+T+G LI AMK  A  V+DP+LK+ L+E +G+GTEATRA+++  L+ R Y
Sbjct  479  KALKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERGY  538

Query  541  LEKSGKHIRSTQRGRELTAALPEALTSPGMTALWEQALDDIAQGRMSLDTFMGRQQQWVR  600
            L K G+ +R+++ +  L  A+P A+T PG TA+WEQALD I  G M+L+TF+++Q  W+ 
Sbjct  539  LLKKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWIT  598

Query  601  HLVSSGREQPFSMTVPVMPPCPLCQGPTRQRKGKHGLFRSCQRYPECKGVVNTQ  654
            +LV   R   +++ +P  P+CPLC ++TRQR GK G F+SC RYP+CKG +  Q
Sbjct  599  QLVQQYRAATLAIKLPEGPACPLCGSATRQRTGKTGPFWSCCRYPDCKGTLPVQ  652

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  555 bits (2094),  Expect = 3e-159, Method: Compositional matrix adjust.
 Identities = 325/650 (50%), Positives = 475/650 (74%), Gaps = 6/650 (0%)

Query  1    MKLFICEKPSQARDLASVLGATSKGDGLLATNDKSIIVTWGFGHLVEQYQPEDYDEVWKR  60
            M+LF+CEKPSQ++D+A VLGA  +G G    N+ + +VTW +GHL+E   PE Y+E  KR
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSG--CYNGAGTVVTWCIGHLIEAAPPEAYGEQYKR  58

Query  61   WAFETLPIIPAQWKMAPKKESKKQYNVVIGLIKKASLVVIATDADREGEMIARELLDLAG  120
            W++E LPIIP +W++ PK  +  Q ++V  L+ +AS +VIATDADREGEMIARE++DL G
Sbjct  59   WSLEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCG  118

Query  121  YRGQIQRCWLSALDDASIRKALQTLKSGKETEALYYAGMGRSRSDWLIGMNFSRLFTLMA  180
            YRG IQR WLSAL+DASIRKAL +LK++ E+ +LY A+++RSR+DWL+GMN+SRLFTL++
Sbjct  119  YRGPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLG  178

Query  181  QAKGYSGKPLSVGRVQSPTLALVVNRDREIANFVPKAHYSLAVQLATASDETFVAGLSIP  240
            +  GY G  LSVGRVQ+PTLALVV RDREIA FV+ +  S+ V L+T+++ +F+A    +
Sbjct  179  RQAGYDG-VLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGH-SFLATWIAA  236

Query  241  EQYLDESGLCLDSRVIQQAEAQIKQVGIAKVITVETKREKKAPPLLYALSDLQGECNRLF  300
            +   D++G CL+    QQA  +++  G A+V++V T R + APPL + L+ LQ+ C+R +
Sbjct  237  DGCSDDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQL  296

Query  301  GFGAQQVLDIAQSLYEEHKITTYPRTDCGYLPESQLTEVPMVIRSLVAADSELQTLLPRL  360
            +++ Q+ LDIAQ+LYE HK TTYPR+D GYLPES L+EVP V+ +++++D+ L+ LL +L
Sbjct  297  ALDVQETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQL  356

Query  361  NLQQKSRAWDDKKITAHHGIIPTIKKADLSKLSEEEMKVYDLIRRRYLAQFLPHLETDKT  420
            +  Q+SRAW+D K++AHHGIIPT+  A+L+ +S+  + VY LIR +YLAQFLPH E D+T
Sbjct  357  DRTQRSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRT  416

Query  421  IATLQSSGHTLIARGNVIVSQGWR-ILFGKNADEDVGSDDEK-QGLPALTANQQCRVTHS  478
             A L  +G+TL A G+ ++  GW+ +L G +AD+  G    + Q LPAL     C+V H 
Sbjct  417  TAQLLCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLSCQVNHV  476

Query  479  EVRTLQTKPPAHYTEGTLLEAMKNAARFVTDPRLKQRLRETEGLGTEATRAGLIQGLIDK  538
            ++++L+T+PP  YT+G L+ AMK  A++VTDPRLKQ+L+ET G+GTEATRA++I+GL+++
Sbjct  477  DLKALKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLER  536

Query  539  GFLIKKKKSLMASAEAIALIDSLPDLLKNPGLTALWEQALNQIAEGSMTLDDFMQRQETF  598
            G+L+KK +++ AS  A  LID++P  + +PG TA+WEQAL+ I  G MTL+ F+ +Q T 
Sbjct  537  GYLLKKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTW  596

Query  599  VRQLIGNCMQQGMSLGNIEIRKCPECGKPMRKINHAKGTFWGCTGYPDCQ  648
            + QL+ +     +++   E   CP CG + R+     G FW+C  YPDC+
Sbjct  597  ITQLVQQYRAATLAIKLPEGPACPLCGSATRQRTGKTGPFWSCCRYPDCK  646

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  555 bits (2094),  Expect = 3e-159, Method: Compositional matrix adjust.
 Identities = 325/650 (50%), Positives = 475/650 (74%), Gaps = 6/650 (0%)

Query  1    MKLFICEKPSQARDLASVLGATSKGDGLLATNDKSIIVTWGFGHLVEQYQPEDYDEVWKR  60
            M+LF+CEKPSQ++D+A VLGA  +G G    N+ + +VTW +GHL+E   PE Y+E  KR
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSG--CYNGAGTVVTWCIGHLIEAAPPEAYGEQYKR  58

Query  61   WAFETLPIIPAQWKMAPKKESKKQYNVVIGLIKKASLVVIATDADREGEMIARELLDLAG  120
            W++E LPIIP +W++ PK  +  Q ++V  L+ +AS +VIATDADREGEMIARE++DL G
Sbjct  59   WSLEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCG  118

Query  121  YRGQIQRCWLSALDDASIRKALQTLKSGKETEALYYAGMGRSRSDWLIGMNFSRLFTLMA  180
            YRG IQR WLSAL+DASIRKAL +LK++ E+ +LY A+++RSR+DWL+GMN+SRLFTL++
Sbjct  119  YRGPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLG  178

Query  181  QAKGYSGKPLSVGRVQSPTLALVVNRDREIANFVPKAHYSLAVQLATASDETFVAGLSIP  240
            +  GY G  LSVGRVQ+PTLALVV RDREIA FV+ +  S+ V L+T+++ +F+A    +
Sbjct  179  RQAGYDG-VLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGH-SFLATWIAA  236

Query  241  EQYLDESGLCLDSRVIQQAEAQIKQVGIAKVITVETKREKKAPPLLYALSDLQGECNRLF  300
            +   D++G CL+    QQA  +++  G A+V++V T R + APPL + L+ LQ+ C+R +
Sbjct  237  DGCSDDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQL  296

Query  301  GFGAQQVLDIAQSLYEEHKITTYPRTDCGYLPESQLTEVPMVIRSLVAADSELQTLLPRL  360
            +++ Q+ LDIAQ+LYE HK TTYPR+D GYLPES L+EVP V+ +++++D+ L+ LL +L
Sbjct  297  ALDVQETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQL  356

Query  361  NLQQKSRAWDDKKITAHHGIIPTIKKADLSKLSEEEMKVYDLIRRRYLAQFLPHLETDKT  420
            +  Q+SRAW+D K++AHHGIIPT+  A+L+ +S+  + VY LIR +YLAQFLPH E D+T
Sbjct  357  DRTQRSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRT  416

Query  421  IATLQSSGHTLIARGNVIVSQGWR-ILFGKNADEDVGSDDEK-QGLPALTANQQCRVTHS  478
             A L  +G+TL A G+ ++  GW+ +L G +AD+  G    + Q LPAL     C+V H 
Sbjct  417  TAQLLCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLSCQVNHV  476

Query  479  EVRTLQTKPPAHYTEGTLLEAMKNAARFVTDPRLKQRLRETEGLGTEATRAGLIQGLIDK  538
            ++++L+T+PP  YT+G L+ AMK  A++VTDPRLKQ+L+ET G+GTEATRA++I+GL+++
Sbjct  477  DLKALKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLER  536

Query  539  GFLIKKKKSLMASAEAIALIDSLPDLLKNPGLTALWEQALNQIAEGSMTLDDFMQRQETF  598
            G+L+KK +++ AS  A  LID++P  + +PG TA+WEQAL+ I  G MTL+ F+ +Q T 
Sbjct  537  GYLLKKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTW  596

Query  599  VRQLIGNCMQQGMSLGNIEIRKCPECGKPMRKINHAKGTFWGCTGYPDCQ  648
            + QL+ +     +++   E   CP CG + R+     G FW+C  YPDC+
Sbjct  597  ITQLVQQYRAATLAIKLPEGPACPLCGSATRQRTGKTGPFWSCCRYPDCK  646

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  555 bits (2094),  Expect = 3e-159, Method: Compositional matrix adjust.
 Identities = 325/650 (50%), Positives = 475/650 (74%), Gaps = 6/650 (0%)

Query  1    MKLFICEKPSQARDLASVLGATSKGDGLLATNDKSIIVTWGFGHLVEQYQPEDYDEVWKR  60
            M+LF+CEKPSQ++D+A VLGA  +G G    N+ + +VTW +GHL+E   PE Y+E  KR
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSG--CYNGAGTVVTWCIGHLIEAAPPEAYGEQYKR  58

Query  61   WAFETLPIIPAQWKMAPKKESKKQYNVVIGLIKKASLVVIATDADREGEMIARELLDLAG  120
            W++E LPIIP +W++ PK  +  Q ++V  L+ +AS +VIATDADREGEMIARE++DL G
Sbjct  59   WSLEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCG  118

Query  121  YRGQIQRCWLSALDDASIRKALQTLKSGKETEALYYAGMGRSRSDWLIGMNFSRLFTLMA  180
            YRG IQR WLSAL+DASIRKAL +LK++ E+ +LY A+++RSR+DWL+GMN+SRLFTL++
Sbjct  119  YRGPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLG  178

Query  181  QAKGYSGKPLSVGRVQSPTLALVVNRDREIANFVPKAHYSLAVQLATASDETFVAGLSIP  240
            +  GY G  LSVGRVQ+PTLALVV RDREIA FV+ +  S+ V L+T+++ +F+A    +
Sbjct  179  RQAGYDG-VLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGH-SFLATWIAA  236

Query  241  EQYLDESGLCLDSRVIQQAEAQIKQVGIAKVITVETKREKKAPPLLYALSDLQGECNRLF  300
            +   D++G CL+    QQA  +++  G A+V++V T R + APPL + L+ LQ+ C+R +
Sbjct  237  DGCSDDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQL  296

Query  301  GFGAQQVLDIAQSLYEEHKITTYPRTDCGYLPESQLTEVPMVIRSLVAADSELQTLLPRL  360
            +++ Q+ LDIAQ+LYE HK TTYPR+D GYLPES L+EVP V+ +++++D+ L+ LL +L
Sbjct  297  ALDVQETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQL  356

Query  361  NLQQKSRAWDDKKITAHHGIIPTIKKADLSKLSEEEMKVYDLIRRRYLAQFLPHLETDKT  420
            +  Q+SRAW+D K++AHHGIIPT+  A+L+ +S+  + VY LIR +YLAQFLPH E D+T
Sbjct  357  DRTQRSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRT  416

Query  421  IATLQSSGHTLIARGNVIVSQGWR-ILFGKNADEDVGSDDEK-QGLPALTANQQCRVTHS  478
             A L  +G+TL A G+ ++  GW+ +L G +AD+  G    + Q LPAL     C+V H 
Sbjct  417  TAQLLCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLSCQVNHV  476

Query  479  EVRTLQTKPPAHYTEGTLLEAMKNAARFVTDPRLKQRLRETEGLGTEATRAGLIQGLIDK  538
            ++++L+T+PP  YT+G L+ AMK  A++VTDPRLKQ+L+ET G+GTEATRA++I+GL+++
Sbjct  477  DLKALKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLER  536

Query  539  GFLIKKKKSLMASAEAIALIDSLPDLLKNPGLTALWEQALNQIAEGSMTLDDFMQRQETF  598
            G+L+KK +++ AS  A  LID++P  + +PG TA+WEQAL+ I  G MTL+ F+ +Q T 
Sbjct  537  GYLLKKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTW  596

Query  599  VRQLIGNCMQQGMSLGNIEIRKCPECGKPMRKINHAKGTFWGCTGYPDCQ  648
            + QL+ +     +++   E   CP CG + R+     G FW+C  YPDC+
Sbjct  597  ITQLVQQYRAATLAIKLPEGPACPLCGSATRQRTGKTGPFWSCCRYPDCK  646

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  555 bits (2094),  Expect = 3e-159, Method: Compositional matrix adjust.
 Identities = 325/650 (50%), Positives = 475/650 (74%), Gaps = 6/650 (0%)

Query  1    MKLFICEKPSQARDLASVLGATSKGDGLLATNDKSIIVTWGFGHLVEQYQPEDYDEVWKR  60
            M+LF+CEKPSQ++D+A VLGA  +G G    N+ + +VTW +GHL+E   PE Y+E  KR
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSG--CYNGAGTVVTWCIGHLIEAAPPEAYGEQYKR  58

Query  61   WAFETLPIIPAQWKMAPKKESKKQYNVVIGLIKKASLVVIATDADREGEMIARELLDLAG  120
            W++E LPIIP +W++ PK  +  Q ++V  L+ +AS +VIATDADREGEMIARE++DL G
Sbjct  59   WSLEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCG  118

Query  121  YRGQIQRCWLSALDDASIRKALQTLKSGKETEALYYAGMGRSRSDWLIGMNFSRLFTLMA  180
            YRG IQR WLSAL+DASIRKAL +LK++ E+ +LY A+++RSR+DWL+GMN+SRLFTL++
Sbjct  119  YRGPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLG  178

Query  181  QAKGYSGKPLSVGRVQSPTLALVVNRDREIANFVPKAHYSLAVQLATASDETFVAGLSIP  240
            +  GY G  LSVGRVQ+PTLALVV RDREIA FV+ +  S+ V L+T+++ +F+A    +
Sbjct  179  RQAGYDG-VLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGH-SFLATWIAA  236

Query  241  EQYLDESGLCLDSRVIQQAEAQIKQVGIAKVITVETKREKKAPPLLYALSDLQGECNRLF  300
            +   D++G CL+    QQA  +++  G A+V++V T R + APPL + L+ LQ+ C+R +
Sbjct  237  DGCSDDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQL  296

Query  301  GFGAQQVLDIAQSLYEEHKITTYPRTDCGYLPESQLTEVPMVIRSLVAADSELQTLLPRL  360
            +++ Q+ LDIAQ+LYE HK TTYPR+D GYLPES L+EVP V+ +++++D+ L+ LL +L
Sbjct  297  ALDVQETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQL  356

Query  361  NLQQKSRAWDDKKITAHHGIIPTIKKADLSKLSEEEMKVYDLIRRRYLAQFLPHLETDKT  420
            +  Q+SRAW+D K++AHHGIIPT+  A+L+ +S+  + VY LIR +YLAQFLPH E D+T
Sbjct  357  DRTQRSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRT  416

Query  421  IATLQSSGHTLIARGNVIVSQGWR-ILFGKNADEDVGSDDEK-QGLPALTANQQCRVTHS  478
             A L  +G+TL A G+ ++  GW+ +L G +AD+  G    + Q LPAL     C+V H 
Sbjct  417  TAQLLCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLSCQVNHV  476

Query  479  EVRTLQTKPPAHYTEGTLLEAMKNAARFVTDPRLKQRLRETEGLGTEATRAGLIQGLIDK  538
            ++++L+T+PP  YT+G L+ AMK  A++VTDPRLKQ+L+ET G+GTEATRA++I+GL+++
Sbjct  477  DLKALKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLER  536

Query  539  GFLIKKKKSLMASAEAIALIDSLPDLLKNPGLTALWEQALNQIAEGSMTLDDFMQRQETF  598
            G+L+KK +++ AS  A  LID++P  + +PG TA+WEQAL+ I  G MTL+ F+ +Q T 
Sbjct  537  GYLLKKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTW  596

Query  599  VRQLIGNCMQQGMSLGNIEIRKCPECGKPMRKINHAKGTFWGCTGYPDCQ  648
            + QL+ +     +++   E   CP CG + R+     G FW+C  YPDC+
Sbjct  597  ITQLVQQYRAATLAIKLPEGPACPLCGSATRQRTGKTGPFWSCCRYPDCK  646

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  555 bits (2094),  Expect = 3e-159, Method: Compositional matrix adjust.
 Identities = 325/650 (50%), Positives = 475/650 (74%), Gaps = 6/650 (0%)

Query  1    MKLFICEKPSQARDLASVLGATSKGDGLLATNDKSIIVTWGFGHLVEQYQPEDYDEVWKR  60
            M+LF+CEKPSQ++D+A VLGA  +G G    N+ + +VTW +GHL+E   PE Y+E  KR
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSG--CYNGAGTVVTWCIGHLIEAAPPEAYGEQYKR  58

Query  61   WAFETLPIIPAQWKMAPKKESKKQYNVVIGLIKKASLVVIATDADREGEMIARELLDLAG  120
            W++E LPIIP +W++ PK  +  Q ++V  L+ +AS +VIATDADREGEMIARE++DL G
Sbjct  59   WSLEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCG  118

Query  121  YRGQIQRCWLSALDDASIRKALQTLKSGKETEALYYAGMGRSRSDWLIGMNFSRLFTLMA  180
            YRG IQR WLSAL+DASIRKAL +LK++ E+ +LY A+++RSR+DWL+GMN+SRLFTL++
Sbjct  119  YRGPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLG  178

Query  181  QAKGYSGKPLSVGRVQSPTLALVVNRDREIANFVPKAHYSLAVQLATASDETFVAGLSIP  240
            +  GY G  LSVGRVQ+PTLALVV RDREIA FV+ +  S+ V L+T+++ +F+A    +
Sbjct  179  RQAGYDG-VLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGH-SFLATWIAA  236

Query  241  EQYLDESGLCLDSRVIQQAEAQIKQVGIAKVITVETKREKKAPPLLYALSDLQGECNRLF  300
            +   D++G CL+    QQA  +++  G A+V++V T R + APPL + L+ LQ+ C+R +
Sbjct  237  DGCSDDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQL  296

Query  301  GFGAQQVLDIAQSLYEEHKITTYPRTDCGYLPESQLTEVPMVIRSLVAADSELQTLLPRL  360
            +++ Q+ LDIAQ+LYE HK TTYPR+D GYLPES L+EVP V+ +++++D+ L+ LL +L
Sbjct  297  ALDVQETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQL  356

Query  361  NLQQKSRAWDDKKITAHHGIIPTIKKADLSKLSEEEMKVYDLIRRRYLAQFLPHLETDKT  420
            +  Q+SRAW+D K++AHHGIIPT+  A+L+ +S+  + VY LIR +YLAQFLPH E D+T
Sbjct  357  DRTQRSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRT  416

Query  421  IATLQSSGHTLIARGNVIVSQGWR-ILFGKNADEDVGSDDEK-QGLPALTANQQCRVTHS  478
             A L  +G+TL A G+ ++  GW+ +L G +AD+  G    + Q LPAL     C+V H 
Sbjct  417  TAQLLCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLSCQVNHV  476

Query  479  EVRTLQTKPPAHYTEGTLLEAMKNAARFVTDPRLKQRLRETEGLGTEATRAGLIQGLIDK  538
            ++++L+T+PP  YT+G L+ AMK  A++VTDPRLKQ+L+ET G+GTEATRA++I+GL+++
Sbjct  477  DLKALKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLER  536

Query  539  GFLIKKKKSLMASAEAIALIDSLPDLLKNPGLTALWEQALNQIAEGSMTLDDFMQRQETF  598
            G+L+KK +++ AS  A  LID++P  + +PG TA+WEQAL+ I  G MTL+ F+ +Q T 
Sbjct  537  GYLLKKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTW  596

Query  599  VRQLIGNCMQQGMSLGNIEIRKCPECGKPMRKINHAKGTFWGCTGYPDCQ  648
            + QL+ +     +++   E   CP CG + R+     G FW+C  YPDC+
Sbjct  597  ITQLVQQYRAATLAIKLPEGPACPLCGSATRQRTGKTGPFWSCCRYPDCK  646

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  554 bits (2090),  Expect = 6e-159, Method: Compositional matrix adjust.
 Identities = 342/655 (53%), Positives = 467/655 (72%), Gaps = 4/655 (0%)

Query  1    MRLFLCEKPSQGRDLAAVLGATRRGEGFLTGNGVTVTWAVGHLLETAPPEVYGQQYGKPW  60
            MRLFLCEKPSQG+D+A VLGA +RG G   G G  VTW +GHL+E+APPE YG+QY K W
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQY-KRW  59

Query  61   SLSVLPILPSRWQVVVKKDTQDQFKVIEKLLRQADEVVIATDADREGEVIARELLDYCGW  120
            SL  LPI+P RW+V  K  T  Q+K++ +L+ QA E+VIATDADREGE+IARE++D CG 
Sbjct  60   SLEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGY  119

Query  121  EGRILRLWFSALDELSVRAALSDLRPGQASVGMYHAGLGRSRADWLVGMNLSRLYTLRAA  180
             G I RLW+SAL++ S+R AL+ L+P+  ++ +Y A+L+RSRADWLVGMNLSRL+TL + 
Sbjct  120  RGPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGR  179

Query  181  EAGFEGVVSVGRVQTPTLALVVRRDREIAAFVPKPFWQVKAVLSASGVSFQASWVPAAVY  240
            +AG++GV+SVGRVQTPTLALVV RDREIA FV+ PFW +   LS++G SF A+W++A   
Sbjct  180  QAGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGC  239

Query  241  TDEEKRCIHQNIAQQVAQLCRQAGVATVTEYETKREKEAAPLVFSLGTLQRACGRMWNMS  300
            +D+  RC++Q  AQQ A+  R AG A V    T R +EA+PL F LGTLQ  C+R   + 
Sbjct  240  SDDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALD  299

Query  301  PQQVLDTAQSLYETHKATTYPRTNCGWLPESMREEIPAVFDAMARTDPSPEFASLLSQLD  360
             Q+ LD AQ+LYETHKATTYPR++ G LPESM  E+PAV+ AM  TDPS  + +LL QLD
Sbjct  300  VQETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPS--LRPLLEQLD  357

Query  361  RGFVSRIWNDKKITAHHGIIPTRNAVQLSGLTETERQVYLLIRRNYLAQFLPLCESDATR  420
            R   SR WND K++AHHGIIPT ++ +L+++++    VY LIR +YLAQFLP  E D T 
Sbjct  358  RTQRSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTT  417

Query  421  ISFDIGGQLFRTTGRTEVLKGW-KVLFTKDEENKNAADDENAGALPPLRKGAQCGVTGAE  479
              +  GGQ +++ G+  ++ GW +VL   + +N ++     +  LP+LR G  C V   +
Sbjct  418  AQLLCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLSCQVNHVD  477

Query  480  VKQLMTQPPAHFTFDTLIGAMMNAAAYVTDLQLRKILKENAGLGTEATRAGIIEQLLSRR  539
            +K L TQPP  +T + LI AM   A  VTD +L++ LKE +G+GTEATRA+II  LL R 
Sbjct  478  LKALKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERG  537

Query  540  FITLKGSKLLATDLGADVIDALPAQLTDPGMTALWEQALDEVAAGRMNLNDFLQRQTAWT  599
            ++  KG  + A+D ++ +IDA+PA +TDPG TA+WEQALD + AG M L+ F+ +Q++W 
Sbjct  538  YLLKKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWI  597

Query  600  ATLVSQGMQQRISIRVPPSPPCPLCGSKTALRRSPKGEFRSCTRYPECKGIISLD  654
            + LV Q     ++I++P +P+CPLCGS T  R +  G F+SC RYP+CKG ++++
Sbjct  598  TQLVQQYRAATLAIKLPEGPACPLCGSATRQRTGKTGPFWSCCRYPDCKGTLPVQ  652

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  553 bits (2086),  Expect = 1e-158, Method: Compositional matrix adjust.
 Identities = 342/672 (51%), Positives = 477/672 (71%), Gaps = 4/672 (0%)

Query  1    MRLFLCEKPSQGRDLAAVLGASRRGEGFMTGNGVTVTWAVGHLLETAPPEVYGQQYGKPW  60
            MRLFLCEKPSQG+D+A VLGA++RG G   G G  VTW +GHL+E+APPE YG+QY K W
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQY-KRW  59

Query  61   SLSALPILPSRWQVVVKKDTQDQFKVIEKLLRQADEVVIATDADREGEVIARELLDYCGW  120
            SL  LPI+P RW+V  K  T  Q+K++ +L+ QA E+VIATDADREGE+IARE++D CG 
Sbjct  60   SLEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGY  119

Query  121  DGRILRLWFSALDELSVRAALSDLRPGQASVGMYHAGLGRSRADWLIGMNLSRLYTLRAA  180
             G I RLW+SAL++ S+R AL+ L+P+  ++ +Y A+L+RSRADWL+GMNLSRL+TL + 
Sbjct  120  RGPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGR  179

Query  181  EAGFEGVVSVGRVQTPTLALVARRDREIAAFVPKPYWQVKATLSASGVSFQASWVPAAVY  240
            +AG++GV+SVGRVQTPTLALV  RDREIA FV+ P+W +   LS++G SF A+W++A   
Sbjct  180  QAGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGC  239

Query  241  ADEEKRCIHQNIAQQVAQLCRQAGVSTVTEYETKREKEAAPLAFSLGTLQRACGKMWNMS  300
            +D+  RC++Q  AQQ A+  R AG + V    T R +EA+PL+F LGTLQ  C++   + 
Sbjct  240  SDDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALD  299

Query  301  PQKVLDTAQSLYETHKATTYPRTDCGWLPKSMREEIPAVFDAMARTDPSPEFASLLSQLD  360
             Q  LD AQ+LYETHKATTYPR+D G LP SM  E+PAV+ AM  TDPS  + +LL QLD
Sbjct  300  VQETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPS--LRPLLEQLD  357

Query  361  RGFASRIWNDKKITAHHGIIPTRNAVQLSSLTETERQVYLLIRRNYLAQFLPLCESDATR  420
            R   SR WND K++AHHGIIPT ++ +L+++++    VY LIR +YLAQFLP  E D T 
Sbjct  358  RTQRSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTT  417

Query  421  ISFDIGGQLFRTTGRTEVLKGW-KVLFtkdeedkdtaeedIAGSLPPLSKGAQCGVTDAE  479
              +  GGQ +++ G+  ++ GW +VL   + ++ D      +  LP+L  G  C V + +
Sbjct  418  AQLLCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLSCQVNHVD  477

Query  480  VKQLMTQPPAHYTFDTLIGAMMNAAAYVTDLQLRKILKENAGLGTEATRAGIIEQLLSRR  539
            +K L TQPP  YT + LI AM   A  VTD +L++ LKE +G+GTEATRA+II  LL R 
Sbjct  478  LKALKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERG  537

Query  540  FITLKGSKLLATDLGADVIDALPPQLTDPGMTALWEQALDEVAAGRMNLNDFLQRQTAWT  599
            ++  KG  + A+D ++ +IDA+P+ +TDPG TA+WEQALD + AG M L+ F+ +Q++W 
Sbjct  538  YLLKKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWI  597

Query  600  STLVSQGMQQRISIRVPPSPPCPLCGSKTALRRSPKGEFRSCTRYPECKGIISLDSGRRK  659
            + LV Q     ++I++P +P+CPLCGS T  R +  G F+SC RYP+CKG +++++GR+ 
Sbjct  598  TQLVQQYRAATLAIKLPEGPACPLCGSATRQRTGKTGPFWSCCRYPDCKGTLPVQNGRQA  657

Query  660  SPARAKSPKTKK  671
            S+ R+ S K ++
Sbjct  658  SAKRSTSRKPRQ  669

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  549 bits (2072),  Expect = 2e-157, Method: Compositional matrix adjust.
 Identities = 332/652 (51%), Positives = 463/652 (72%), Gaps = 2/652 (0%)

Query  1    MRLFICEKPSQGRDLAAVLGATQRGDGFLAGSGITVTWAVGHLLETAPPEAYGQQYGKPW  60
            MRLF+CEKPSQG+D+A VLGA QRG G   G+G  VTW +GHL+E+APPEAYG+QY K W
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQY-KRW  59

Query  61   TLAALPIIPSPWQVVVKKETQHQFKIIERLLRQVDEVIIATDADREGEVIARELLDYCRW  120
            +L  LPIIP  W+V  K  T  Q+KI+ +L+ Q  E++IATDADREGE+IARE++D C  
Sbjct  60   SLEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGY  119

Query  121  EGPVQRLWLSSLDELSIRAALQNLRPGGETLGMYHAGLGRARADWLTGMNLSRLYTLRAA  180
             GP+QRLWLS+L++ SIR AL  L+P++E+L +Y A+L+R+RADWL GMNLSRL+TL + 
Sbjct  120  RGPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGR  179

Query  181  EAGFDGVVSVGRVQSPTLALVVRRDREIAAFVPKPYWQVKAQLSAGGITFPAQWVPAKVY  240
            +AG+DGV+SVGRVQ+PTLALVV RDREIA FV+ P+W +   LS+GG +F A W++A   
Sbjct  180  QAGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGC  239

Query  241  TDEEKRCIHQNIAQQVVQICRQSGEATVTECETKREKASPPLAFSLGTLQQAASRLWDMS  300
            +D+  RC++Q  AQQ  +  R +G A V    T R + +PPL+F LGTLQ+  SR   + 
Sbjct  240  SDDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALD  299

Query  301  PQQVLDTAQSLYEKHKATSYPRTDCGYLPESMREEIPALLDAIGRTDPECLPLLSQLDAS  360
             Q+ LD AQ+LYE HKAT+YPR+D GYLPESM  E+PA+L A+  TDP   PLL QLD +
Sbjct  300  VQETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRT  359

Query  361  LVSRIWNDKKITAHHGIIPTRNAFQLSALSETERQVYMLIRRNYLAQFLPLHESDITRLA  420
              SR WND K++AHHGIIPT ++ +L+A+S+    VY LIR +YLAQFLP  E D T   
Sbjct  360  QRSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQ  419

Query  421  FDIGGQLFRTTGRTEVVKGW-KVLFGKaeeegsaaddeavvaLPPLKKDDRCGVTGAEVV  479
            +  GGQ +++ G+  ++ GW +VL G   +++ +        LP+L+ +  C V   ++ 
Sbjct  420  LLCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLSCQVNHVDLK  479

Query  480  QLMTRPPAHYTFATLIGAMMNAAAFVTDVALRKVLKDNAGLGTEATRAGIVEQLLNRRFI  539
             L T+PP  YT + LI AM   A +VTD  L++ LK+ +G+GTEATRA+I+  LL+R ++
Sbjct  480  ALKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERGYL  539

Query  540  VRKSSKLLATDLGSDVIDSLPPQLTEPGMTALWEQALDEVAAGRMSLSDFLQRQTGWTRN  599
            ++K+  + A+D ++ +ID++P+ +T+PG TA+WEQALD + AG M+L  F+ +Q+ W  +
Sbjct  540  LKKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWITQ  599

Query  600  LVSQGAQQQVSIRIPPTPPCPLCGGKTRLRKGQKGDFWSCQRYPDCKGVINI  651
            LV Q     ++I++P  P+CPLCG+ TR R G+ G FWSC RYPDCKG + +
Sbjct  600  LVQQYRAATLAIKLPEGPACPLCGSATRQRTGKTGPFWSCCRYPDCKGTLPV  651

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  548 bits (2070),  Expect = 3e-157, Method: Compositional matrix adjust.
 Identities = 320/646 (50%), Positives = 467/646 (73%), Gaps = 2/646 (0%)

Query  1    MQLFLCEKPSQAKDIARVLGISKREQGFISGGNIVVTWAVGHLLETASPEAYGEQYGRPW  60
            M+LFLCEKPSQ+KDIARVLG ++R  G  +G+  VVTW +GHL+E+A+PEAYGEQY R W
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQYKR-W  59

Query  61   RADVLPVLPEAWKMVVKEQTKSQFTVISKLLKKASEVVIATDADREGEVIARELMEYCRY  120
              + LP++PE W++  K  T +Q+ ++ +L+ +ASE+VIATDADREGE+IARE+++ C Y
Sbjct  60   SLEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGY  119

Query  121  SGAVRRLWLSALDEASVKEALSSILPGEKTALLYDAGKGRSQADWLIGMNLTRLYTLKAR  180
             G+++RLWLSAL++AS++ AL+++ P+  +  LY A+ +RS+ADWL+GMNL+RL+TL +R
Sbjct  120  RGPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGR  179

Query  181  DSGVSEVLSVGRVQTPTLAMVVNRDNEITSFVPKPWWQVHALIEKEGVRFRAVWVPVEQY  240
            ++G   VLSVGRVQTPTLA+VV RD EI+ FV+ P W ++  +   G  F A W++ +  
Sbjct  180  QAGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGC  239

Query  241  CDEEKRCINPQAARAVGQLCQQQGRAVVLEVTQKREKTAAPLCFDLGTLQQVCSRKFGMG  300
             D+  RC++  +A+  ++  +  G A V+ VT  R + A+PL FDLGTLQ+VCSR+++++
Sbjct  240  SDDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALD  299

Query  301  ANDVLAIAQSLYETHKATTYPRTDCGFLPTSMQQEIPDVLAAVAKSDPAVAPVLNQLDRK  360
             ++ L IAQ+LYETHKATTYPR+D G+LP SM  E+P VLAA+  +DP++ P+L+QLDR 
Sbjct  300  VQETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRT  359

Query  361  FVSRVWNDKKITAHHAIIPTRQAFDLSRLSADELKVYHLIRQHYFAQFLPLQESDVTEAS  420
              SR WND K++AHH+IIPT ++ +L+ +S   L VY+LIR HY+AQFLP  E D T A 
Sbjct  360  QRSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQ  419

Query  421  FNIGGQLFRTRGKVGVVTGWKSLFQAekdddeedvdgd-SMALPALAKGDICAVTGSEVK  479
            +  GGQ +++ GK  ++ GW  ++ +   D+ ++     S  LPAL  G  C V   ++K
Sbjct  420  LLCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLSCQVNHVDLK  479

Query  480  DMKTSPPKPFTEGTLIAAMKNAASFVSDPKLKKVLRDNAGLGTEATRAAVLETLFKRHYL  539
             +KT PPKP+T+G LI AMK  A +V+DP+LK+ L++ +G+GTEATRA+++  L+ R YL
Sbjct  480  ALKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERGYL  539

Query  540  EKKGKHIHSTQMARELIAALPETLTSPGMTALWEQALDDISQGKMSLAVFMQKQLQWTRH  599
             KKG+ +++++ A  LI A+P ++T PG TA+WEQALD I  G M+L  F+ KQ  W  +
Sbjct  540  LKKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWITQ  599

Query  600  LVEKGRQDSVKITAPVTPPCPLCKGPTrkrkgkkgDFWGCVRYPDC  645
            LV++ R  ++ I  P  P+CPLC ++TR+R GK G FW+C RYPDC
Sbjct  600  LVQQYRAATLAIKLPEGPACPLCGSATRQRTGKTGPFWSCCRYPDC  645

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  547 bits (2065),  Expect = 6e-157, Method: Compositional matrix adjust.
 Identities = 334/656 (51%), Positives = 472/656 (72%), Gaps = 5/656 (0%)

Query  1    MQLYLCEKPSQGKDIGAILGATQRKQGYLAGAGVIVTWAIGHLLEQAQPETYGEQFGSPW  60
            M+L+LCEKPSQGKDI+ +LGA QR  G   GAG +VTW IGHL+E A PE+YGEQ+   W
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQY-KRW  59

Query  61   RESVLPIVPTQWKMAIKKDTADQFAVIRGLLKQVDSVVIATDADREGEVIARELLEHCHF  120
                LPI+P +W++  K  TA Q+ +++ L+ Q   +VIATDADREGE+IARE+++ C +
Sbjct  60   SLEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGY  119

Query  121  TGPVQRLWLSALDEASIRHALANKLPGEKTAPLYEAGLARSRADWMTGMNLTRLYTLKAR  180
             GP+QRLWLSAL++ASIR AL+   P+  + PLY A+LARSRADW+ GMNL+RL+TL +R
Sbjct  120  RGPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGR  179

Query  181  EQGYGEVLSIGRVQTPTLALVVNRDRDIANFISKPYWQVRGTLQKGGIAFPANWVPAANY  240
            + GY+ VLS+GRVQTPTLALVV RDR+IA F+S P+W +   L  GG +F A W++A   
Sbjct  180  QAGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGC  239

Query  241  CDEEKRCIQQNVAQAVVQRCQQTAHAVVLEVGTERKKESAPLAFDLGTLQQACSRKWGMS  300
             D+  RC+QQ  AQ   +R + ++ A V+ V TER +E++PL+FDLGTLQ+ CSR+ ++ 
Sbjct  240  SDDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALD  299

Query  301  ANQVLSIAQSLYETHKATTYPRTDCGYLPTSMREEVADVLSAVTRTDPTLNESVARLDRA  360
             ++ L IAQ+LYETHKATTYPR+D GYLP SM  EV+ VL+A+  TDP+L   + +LDR+
Sbjct  300  VQETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRT  359

Query  361  FVSRIWNDKKITAHHGIIPTKQPFDLSKLSADELKVYQLIRQHYLAQFLPLHEVDVTEAT  420
              SR WND K++AHHGIIPT +P +L+ +S   L VY+LIR HYLAQFLP  E D T A 
Sbjct  360  QRSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQ  419

Query  421  FNIGGQLFRTRGKVEAVAGW-KVLFQHDVSEAKEEPADTDDVRLPALVKGETVAVAGAEL  479
            +  GGQ +++ GK   ++GW +VL   +  +A  E+    +V LPAL  G +  V   +L
Sbjct  420  LLCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQV-LPALREGLSCQVNHVDL  478

Query  480  KTLQTKPPGHFTDGTLIAAMKNAAAFVSDPQLKKVLKENAGLGTEATRAGILETLFKRGY  539
            K+L+T+PP  +T+G LI AMK  A +V+DP+LK+ LKE +G+GTEATRA+I+  L+ RGY
Sbjct  479  KALKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERGY  538

Query  540  LEKKGKYLLSTPIAGELIDALPTALTNPGMTALWEQALDEIAQGQMTLDTFMSRQAQWTG  599
            L KKG+ + ++  AG LIDA+P+A+T+PG TA+WEQALD I  G+MTL+TF+++Q+ W  
Sbjct  539  LLKKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWIT  598

Query  600  HLVEKGKTQAVKFtappsppcptcsGSMrrragkkgggaFWGCSNYPTCQGVINID  655
            +LV++ ++ ++ +  P +P+CP C+++   R      G+FW+C  YP C+G + ++
Sbjct  599  QLVQQYRAATLAIKLPEGPACPLCGSA--TRQRTGKTGPFWSCCRYPDCKGTLPVQ  652

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  547 bits (2065),  Expect = 6e-157, Method: Compositional matrix adjust.
 Identities = 334/656 (51%), Positives = 472/656 (72%), Gaps = 5/656 (0%)

Query  1    MQLYLCEKPSQGKDIGAILGATQRKQGYLAGAGVIVTWAIGHLLEQAQPETYGEQFGSPW  60
            M+L+LCEKPSQGKDI+ +LGA QR  G   GAG +VTW IGHL+E A PE+YGEQ+   W
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQY-KRW  59

Query  61   RESVLPIVPTQWKMAIKKDTADQFAVIRGLLKQVDSVVIATDADREGEVIARELLEHCHF  120
                LPI+P +W++  K  TA Q+ +++ L+ Q   +VIATDADREGE+IARE+++ C +
Sbjct  60   SLEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGY  119

Query  121  TGPVQRLWLSALDEASIRHALANKLPGEKTAPLYEAGLARSRADWMTGMNLTRLYTLKAR  180
             GP+QRLWLSAL++ASIR AL+   P+  + PLY A+LARSRADW+ GMNL+RL+TL +R
Sbjct  120  RGPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGR  179

Query  181  EQGYGEVLSIGRVQTPTLALVVNRDRDIANFISKPYWQVRGTLQKGGIAFPANWVPAANY  240
            + GY+ VLS+GRVQTPTLALVV RDR+IA F+S P+W +   L  GG +F A W++A   
Sbjct  180  QAGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGC  239

Query  241  CDEEKRCIQQNVAQAVVQRCQQTAHAVVLEVGTERKKESAPLAFDLGTLQQACSRKWGMS  300
             D+  RC+QQ  AQ   +R + ++ A V+ V TER +E++PL+FDLGTLQ+ CSR+ ++ 
Sbjct  240  SDDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALD  299

Query  301  ANQVLSIAQSLYETHKATTYPRTDCGYLPTSMREEVADVLSAVTRTDPTLNESVARLDRA  360
             ++ L IAQ+LYETHKATTYPR+D GYLP SM  EV+ VL+A+  TDP+L   + +LDR+
Sbjct  300  VQETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRT  359

Query  361  FVSRIWNDKKITAHHGIIPTKQPFDLSKLSADELKVYQLIRQHYLAQFLPLHEVDVTEAT  420
              SR WND K++AHHGIIPT +P +L+ +S   L VY+LIR HYLAQFLP  E D T A 
Sbjct  360  QRSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQ  419

Query  421  FNIGGQLFRTRGKVEAVAGW-KVLFQHDVSEAKEEPADTDDVRLPALVKGETVAVAGAEL  479
            +  GGQ +++ GK   ++GW +VL   +  +A  E+    +V LPAL  G +  V   +L
Sbjct  420  LLCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQV-LPALREGLSCQVNHVDL  478

Query  480  KTLQTKPPGHFTDGTLIAAMKNAAAFVSDPQLKKVLKENAGLGTEATRAGILETLFKRGY  539
            K+L+T+PP  +T+G LI AMK  A +V+DP+LK+ LKE +G+GTEATRA+I+  L+ RGY
Sbjct  479  KALKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERGY  538

Query  540  LEKKGKYLLSTPIAGELIDALPTALTNPGMTALWEQALDEIAQGQMTLDTFMSRQAQWTG  599
            L KKG+ + ++  AG LIDA+P+A+T+PG TA+WEQALD I  G+MTL+TF+++Q+ W  
Sbjct  539  LLKKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWIT  598

Query  600  HLVEKGKTQAVKFtappsppcptcsGSMrrragkkgggaFWGCSNYPTCQGVINID  655
            +LV++ ++ ++ +  P +P+CP C+++   R      G+FW+C  YP C+G + ++
Sbjct  599  QLVQQYRAATLAIKLPEGPACPLCGSA--TRQRTGKTGPFWSCCRYPDCKGTLPVQ  652

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  547 bits (2065),  Expect = 6e-157, Method: Compositional matrix adjust.
 Identities = 334/656 (51%), Positives = 472/656 (72%), Gaps = 5/656 (0%)

Query  1    MQLYLCEKPSQGKDIGAILGATQRKQGYLAGAGVIVTWAIGHLLEQAQPETYGEQFGSPW  60
            M+L+LCEKPSQGKDI+ +LGA QR  G   GAG +VTW IGHL+E A PE+YGEQ+   W
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQY-KRW  59

Query  61   RESVLPIVPTQWKMAIKKDTADQFAVIRGLLKQVDSVVIATDADREGEVIARELLEHCHF  120
                LPI+P +W++  K  TA Q+ +++ L+ Q   +VIATDADREGE+IARE+++ C +
Sbjct  60   SLEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGY  119

Query  121  TGPVQRLWLSALDEASIRHALANKLPGEKTAPLYEAGLARSRADWMTGMNLTRLYTLKAR  180
             GP+QRLWLSAL++ASIR AL+   P+  + PLY A+LARSRADW+ GMNL+RL+TL +R
Sbjct  120  RGPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGR  179

Query  181  EQGYGEVLSIGRVQTPTLALVVNRDRDIANFISKPYWQVRGTLQKGGIAFPANWVPAANY  240
            + GY+ VLS+GRVQTPTLALVV RDR+IA F+S P+W +   L  GG +F A W++A   
Sbjct  180  QAGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGC  239

Query  241  CDEEKRCIQQNVAQAVVQRCQQTAHAVVLEVGTERKKESAPLAFDLGTLQQACSRKWGMS  300
             D+  RC+QQ  AQ   +R + ++ A V+ V TER +E++PL+FDLGTLQ+ CSR+ ++ 
Sbjct  240  SDDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALD  299

Query  301  ANQVLSIAQSLYETHKATTYPRTDCGYLPTSMREEVADVLSAVTRTDPTLNESVARLDRA  360
             ++ L IAQ+LYETHKATTYPR+D GYLP SM  EV+ VL+A+  TDP+L   + +LDR+
Sbjct  300  VQETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRT  359

Query  361  FVSRIWNDKKITAHHGIIPTKQPFDLSKLSADELKVYQLIRQHYLAQFLPLHEVDVTEAT  420
              SR WND K++AHHGIIPT +P +L+ +S   L VY+LIR HYLAQFLP  E D T A 
Sbjct  360  QRSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQ  419

Query  421  FNIGGQLFRTRGKVEAVAGW-KVLFQHDVSEAKEEPADTDDVRLPALVKGETVAVAGAEL  479
            +  GGQ +++ GK   ++GW +VL   +  +A  E+    +V LPAL  G +  V   +L
Sbjct  420  LLCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQV-LPALREGLSCQVNHVDL  478

Query  480  KTLQTKPPGHFTDGTLIAAMKNAAAFVSDPQLKKVLKENAGLGTEATRAGILETLFKRGY  539
            K+L+T+PP  +T+G LI AMK  A +V+DP+LK+ LKE +G+GTEATRA+I+  L+ RGY
Sbjct  479  KALKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERGY  538

Query  540  LEKKGKYLLSTPIAGELIDALPTALTNPGMTALWEQALDEIAQGQMTLDTFMSRQAQWTG  599
            L KKG+ + ++  AG LIDA+P+A+T+PG TA+WEQALD I  G+MTL+TF+++Q+ W  
Sbjct  539  LLKKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWIT  598

Query  600  HLVEKGKTQAVKFtappsppcptcsGSMrrragkkgggaFWGCSNYPTCQGVINID  655
            +LV++ ++ ++ +  P +P+CP C+++   R      G+FW+C  YP C+G + ++
Sbjct  599  QLVQQYRAATLAIKLPEGPACPLCGSA--TRQRTGKTGPFWSCCRYPDCKGTLPVQ  652

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  546 bits (2060),  Expect = 2e-156, Method: Compositional matrix adjust.
 Identities = 331/656 (51%), Positives = 472/656 (72%), Gaps = 5/656 (0%)

Query  1    MQLYLCEKPSQGKDIGAILGATQRKQGYLAGAGVIVTWAIGHLLEQAQPETYGEQFGSPW  60
            M+L+LCEKPSQGKDI+ +LGA QR  G   GAG +VTW IGHL+E A PE+YGEQ+   W
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQY-KRW  59

Query  61   RESVLPIVPTQWKMAVKKDTADQFAVIRGLLKQVDSVVIATDADREGEVIARELLEHCHF  120
                LPI+P +W++  K  TA Q+ +++ L+ Q   +VIATDADREGE+IARE+++ C +
Sbjct  60   SLEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGY  119

Query  121  TGPVQRLWLSALDEASIRHALANKLPGEKTAPLYEAGLARSRADWMTGMNLTRLYTLKAR  180
             GP+QRLWLSAL++ASIR AL+   P+  + PLY A+LARSRADW+ GMNL+RL+TL +R
Sbjct  120  RGPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGR  179

Query  181  EQGYGEVLSIGRVQTPTLALVVNRDRDITNFISKPYWQVRATLQKGGITFPANWVPAANY  240
            + GY+ VLS+GRVQTPTLALVV RDR+I+ F+S P+W +   L  GG +F A W++A   
Sbjct  180  QAGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGC  239

Query  241  CDEEKRCIQQNVAQAVVQRCQQTAHAVVLEVGTERKKESAPLAFDLGTLQQACSRKWGMS  300
             D+  RC+QQ  AQ   +R + ++ A V+ V TER +E++PL+FDLGTLQ+ CSR+ ++ 
Sbjct  240  SDDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALD  299

Query  301  ANQVLSIAQSLYETHKATTYPRTDCGYLPTSMREEVADVLSAVTRTDPTLNESVARLDRA  360
             ++ L IAQ+LYETHKATTYPR+D GYLP SM  EV+ VL+A+  TDP+L   + +LDR+
Sbjct  300  VQETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRT  359

Query  361  FVSRIWNDKKITAHHGIIPTKQPFDLSKLSADELKVYQLIRQHYLAQYLSLHEVDVTEAT  420
              SR WND K++AHHGIIPT +P +L+ +S   L VY+LIR HYLAQ+L+  E D T A 
Sbjct  360  QRSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQ  419

Query  421  FNIGGQLFRTRGKVEAVAGW-KVLFQHDVSEAKEEPADTDDVRLPALVKGETVAVAGAEL  479
            +  GGQ +++ GK   ++GW +VL   +  +A  E+    +V LPAL  G +  V   +L
Sbjct  420  LLCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQV-LPALREGLSCQVNHVDL  478

Query  480  KTLQTKPPGHFTDGTLIAAMKNAAAFVSDPQLKKVLKENAGLGTEATRAGILDTLFKRGY  539
            K+L+T+PP  +T+G LI AMK  A +V+DP+LK+ LKE +G+GTEATRA+I+  L+ RGY
Sbjct  479  KALKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERGY  538

Query  540  LEKKGKYLLSTPIAGELIDALPTALTNPGMTALWEQALDEIAQGQMTLDTFMSRQAQWTG  599
            L KKG+ + ++  AG LIDA+P+A+T+PG TA+WEQALD I  G+MTL+TF+++Q+ W  
Sbjct  539  LLKKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWIT  598

Query  600  HLVEKGKTQAVKFtappsppcptcsGSMrrragkkgggaFWGCSNYPTCQGVINID  655
            +LV++ ++ ++ +  P +P+CP C+++   R      G+FW+C  YP C+G + ++
Sbjct  599  QLVQQYRAATLAIKLPEGPACPLCGSA--TRQRTGKTGPFWSCCRYPDCKGTLPVQ  652

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  538 bits (2031),  Expect = 3e-154, Method: Compositional matrix adjust.
 Identities = 328/655 (51%), Positives = 466/655 (72%), Gaps = 3/655 (0%)

Query  1    MQLYLCEKPSQGKDIGAILGATQRKQGYLVGAGVIVTWAIGHLLEQAQPETYGEQFGSPW  60
            M+L+LCEKPSQGKDI+ +LGA QR  G   GAG +VTW IGHL+E A PE+YGEQ+   W
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQY-KRW  59

Query  61   RESVLPIVPAQWKMAVKKDTADQFAVIRGLLKQVDSVVIATDADREGEVIARELLEHCHF  120
                LPI+P +W++  K  TA Q+ +++ L+ Q   +VIATDADREGE+IARE+++ C +
Sbjct  60   SLEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGY  119

Query  121  TGPVQRLWLSALDEASIRHALANKLPGEKTAPLYEAGLARSRADWMTGMNLTRLYTLKAR  180
             GP+QRLWLSAL++ASIR AL+   P+  + PLY A+LARSRADW+ GMNL+RL+TL +R
Sbjct  120  RGPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGR  179

Query  181  EQGYGEVLSIGRVQTPTLALVVNRDRDIANFISKPYWQVRTMLQKDGIAFPANWVPAVNY  240
            + GY+ VLS+GRVQTPTLALVV RDR+IA F+S P+W +   L  +G +F A W++A   
Sbjct  180  QAGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGC  239

Query  241  CDEEKRCIQQNVAQAVVQLCQQTANAVVLDVGTERKKESAPLAFDLGILQQACSRKWGMS  300
             D+  RC+QQ  AQ   +  + +++A V+ V TER +E++PL+FDLG LQ+ CSR+ ++ 
Sbjct  240  SDDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALD  299

Query  301  ANQVLSIAQSLYETHKATTYPRTDCGYLPTSMREEVADVLSAVTRTDPTQSESVARLDRT  360
             ++ L IAQ+LYETHKATTYPR+D GYLP SM  EV+ VL+A+  TDP+    + +LDRT
Sbjct  300  VQETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRT  359

Query  361  FVSRIWNDKKITAHHGIIPTKQPFDLSKLSADELKVYQLIRQHYLAQFLPLHEVDVTEAT  420
              SR WND K++AHHGIIPT +P +L+ +S   L VY+LIR HYLAQFLP  E D T A 
Sbjct  360  QRSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQ  419

Query  421  FNIGGQLFRTRGKVEAVAGWKALFQHDASEAKEEPADTDDVRLPALVKGEAVSVAGAELK  480
            +  GGQ +++ GK   ++GW  ++    ++  +  A      LPAL  G +  V   +LK
Sbjct  420  LLCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLSCQVNHVDLK  479

Query  481  TLQTKPPGHFTDGTLIAAMKNAAAFVSDPQLKKVLKENAGLGTEATRAGILETLFKRGYL  540
            +L+T+PP  +T+G LI AMK  A +V+DP+LK+ LKE +G+GTEATRA+I+  L+ RGYL
Sbjct  480  ALKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERGYL  539

Query  541  EKKGKFLLSTPIAGELIDALPTALTNPGMTALWEQALDEIAQGQMTLDTFMSRQAQWTGH  600
             KKG+ + ++  AG LIDA+P+A+T+PG TA+WEQALD I  G+MTL+TF+++Q+ W  +
Sbjct  540  LKKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWITQ  599

Query  601  LVEKGKAQAVKFtappsppcptcsGTMrrragkkgggaFWGCSNYPTCQGIINID  655
            LV++ +A ++ +  P +P+CP C+++   R      G+FW+C  YP C+G + ++
Sbjct  600  LVQQYRAATLAIKLPEGPACPLCGSA--TRQRTGKTGPFWSCCRYPDCKGTLPVQ  652

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  538 bits (2030),  Expect = 4e-154, Method: Compositional matrix adjust.
 Identities = 323/650 (50%), Positives = 463/650 (72%), Gaps = 10/650 (1%)

Query  1    MKLFLCEKPSQGRDIAKVLGATQKGEGYLSTADGTIVVTWARGHLVEHFSPEQYDPALKA  60
            M+LFLCEKPSQG+DIA+VLGA Q+G G  + A+   VVTW  GHL+E  +PE Y+   K 
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAG--TVVTWCIGHLIEAAPPEAYGEQYKR  58

Query  61   WRLDTLPIIPSQWQVSPKPDAKKEYKTVMTLLKKARTVVISTDIDREGETIARELLDLAG  120
            W L+ LPIIP +W+V PK+ +  + K V  L+ +A  +VI+TD DREGE IARE++DL G
Sbjct  59   WSLEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCG  118

Query  121  YRGHIQRLWITALDEISVRKALSRLKTNEETLPLYYAGLARSRADWLIGMNFSRMFTLLA  180
            YRG IQRLW++AL++ S+RKAL+ LK + E+LPLY A+LARSRADWL+GMN+SR+FTLL+
Sbjct  119  YRGPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLG  178

Query  181  QQQGYQGPPLSVGRVQSPTLALVVNRDKEIAHFVPTYHYALMVQVCGTNAQSFEASLLVP  240
            +Q GY+G  LSVGRVQ+PTLALVV RD+EIA+FV+    ++ V + +T ++SF A+ + +
Sbjct  179  RQAGYDGV-LSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGL-STGGHSFLATWIAA  236

Query  241  EQYCDEEGRCLEIKVLqqaeqqirqagqVCVQNVETKREKESPPLLFALSDLQAECNRLY  300
            +   D+ GRCL+    QQA +++R AG   V  V T R +E+PPL F L+ LQ  C+R  
Sbjct  237  DGCSDDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQL  296

Query  301  DLGTQQVLDIAQSLYEKHKATTYPRTDCGYLPEAQLLEVPQVINSLMQSDAKLQPLRVQL  360
             L+ Q+ LDIAQ+LYE HKATTYPR+D GYLPE+ L EVP V+ +++ +D+ L+PL  QL
Sbjct  297  ALDVQETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQL  356

Query  361  NLSQKSRAWNDKKITAHHGIIPTTQPVDIAKMNENEFKVYDLIRRRYLAQFLPHFEVDKT  420
            + +Q+SRAWND K++AHHGIIPT +P ++A ++++ + VY LIR +YLAQFLPH+E D+T
Sbjct  357  DRTQRSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRT  416

Query  421  RVRLSCGEHQCIAKGQVIVSAGWKALFRASKEEQGE------KQGLPILNSGQMLKVMNT  474
              +L CG +   A G+ ++ +GW  ++ ++  ++++       Q LP L  G   +V + 
Sbjct  417  TAQLLCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLSCQVNHV  476

Query  475  EIKSLKTTPPAHYTEGTLLTAMVNVARFVTDERLKKQLRETEGLGTEATRASIMKTLYDR  534
            ++K+LKT PP  YT+G L+ AM  VA++VTD RLK++L+ET G+GTEATRASI+K L +R
Sbjct  477  DLKALKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLER  536

Query  535  GYIKKKGKSIVATDAGVMLIDNLPTVLKDPGLTALWEQALNQIAENQMSLQEFMQKQEQF  594
            GY+ KKG+++ A+DA+  LID +P+ + DPG TA+WEQAL+ I   +M+L+ F+ KQ   
Sbjct  537  GYLLKKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTW  596

Query  595  VLHLIQTCGHQGIKMGNIDIKKCPQCGKPLRKMKGKNGDFLGCTGYPKCK  644
            + +L+Q      + +   +   CP CG + R+  GK G F +C  YP CK
Sbjct  597  ITQLVQQYRAATLAIKLPEGPACPLCGSATRQRTGKTGPFWSCCRYPDCK  646

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  537 bits (2027),  Expect = 6e-154, Method: Compositional matrix adjust.
 Identities = 301/651 (47%), Positives = 461/651 (71%), Gaps = 1/651 (0%)

Query  2    MRLFLCEKPSQGRDIARFIGATQRGKGFLSGTGTVVTWAFGHLLEVASPEEYGAQFGKPW  61
            MRLFLCEKPSQG+DIAR +GA QRG G  +G+GTVVTW +GHL+E A+PE YG Q+ K W
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQY-KRW  59

Query  62   RMDVLPILPTEWKMVVKQSSADQFAVISRLLKQADEVVIATDADREGEVLARELLDYCHF  121
             ++ LPI+P  W++  K ++A Q+ ++ +L+ QA E+VIATDADREGE++ARE++D C +
Sbjct  60   SLEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGY  119

Query  122  TGNVKRLWLSALDDASIRKGLDNLLPGEKTVRLYYAGMGRSKADWLIGMNLTRIYTLKAS  181
             G ++RLWLSAL+DASIRK+L+ L P+  ++ LY A+++RS+ADWL+GMNL+R++TL + 
Sbjct  120  RGPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGR  179

Query  182  EQGIDELLSIGRVQTPTLALVVQRDSDIENFSPKPYWQVFADIEKAGMTFRAQWVPAAGY  241
            + G D +LS+GRVQTPTLALVV RD +I  F + P+W +  ++  +G +F A W++A G 
Sbjct  180  QAGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGC  239

Query  242  CDDEKRCIQHNAALAVEQLCKQTATTSVVDVLLKREKTPAPLCFSLSVLQKACSDKWGMI  301
             DD  RC+Q+ +A    +  + ++++ VV V   R + ++PL F L+ LQ  CS + ++ 
Sbjct  240  SDDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALD  299

Query  302  AQKVLEIAQSLYEVHKATTYPRTDCGYLPESMKGEVSDVLSAILQSDPAATSLIKDADRS  361
             Q  L+IAQ+LYE HKATTYPR+D GYLPESM +EV+ VL+A+L +DP+  +L+ + DR+
Sbjct  300  VQETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRT  359

Query  362  FVSRIWNDKKISAHHAIIPTKQPFDISKLSDDELNVYQLIRLHYFAQFFPLHESDVTDVT  421
              SR WND K+SAHH+IIPT +P +++ +SD  L VY+LIR HY+AQF+P  E D T   
Sbjct  360  QRSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQ  419

Query  422  FNLGGQLFKTRGRVSVVIGWKKLFFNDKEPDIQSDENGSQGSLPVLHNGDICNVLDCEVK  481
            +  GGQ +++ G+  ++ GW +++      + +++       LP L++G  C+V + ++K
Sbjct  420  LLCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLSCQVNHVDLK  479

Query  482  AQQTKPPSRFTDGTLIDAMKNSASFISDPTLKKILRDNAGLGTEATRANILDVLFKRNYL  541
            A +T+PP  +T+G LI AMK  A +++DP LK+ L++ +G+GTEATRA+I+  L+ R YL
Sbjct  480  ALKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERGYL  539

Query  542  KRREKFIYSTQLARELISQLPEALTNPGMTALWEQALDDVAEGRMSLDAFLQKQKEWTLR  601
             ++ + + +++ A  LI  +P A+T+PG TA+WEQALD +  G M+L++F+ KQ  W  +
Sbjct  540  LKKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWITQ  599

Query  602  LVDRGRQQAIKLTAPVSPLCPQCGGIMRKRNSDNGVFWGCVKYPLCKGIIS  652
            LV++ R  ++ +  P +P CP CG+  R+R +  G FW+C +YP CKG ++
Sbjct  600  LVQQYRAATLAIKLPEGPACPLCGSATRQRTGKTGPFWSCCRYPDCKGTLP  650

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  536 bits (2022),  Expect = 2e-153, Method: Compositional matrix adjust.
 Identities = 310/666 (47%), Positives = 472/666 (71%), Gaps = 8/666 (1%)

Query  1    MPLYLCEKPSQARDIARVLGVKQRGQGYLFGDSITVTWAIGHLLEMAAPEHYGEQFGPPW  60
            M L+LCEKPSQ++DIARVLG  QRG G   G +  VTW IGHL+E A+PE YGEQ+   W
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQY-KRW  59

Query  61   RMEPLPVLPVQWQWTVKKETADQFAVIRQLLKQADEVIIATDADREGEVIARELLEYCRF  120
             +E LP++P +W+   K  TA Q+ +++QL+ QA E++IATDADREGE+IARE+++ C +
Sbjct  60   SLEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGY  119

Query  121  TGPVRRLWLSALDETSIRQALAAILLGEQTEPLWQAGLGRARADWLMGINLTRLYTLKAQ  180
             GP++RLWLSAL+++SIR+AL+A+  + ++ PL  A+L+R+RADWL+G+NL+RL+TL ++
Sbjct  120  RGPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGR  179

Query  181  AQGFGEVLSIGRVQTPTLALVVNRDNDIARFEPKPYWQVMAALQKDDISFRVKWLPAPDD  240
              G++ VLS+GRVQTPTLALVV RD +IARF + P+W +  +L  ++ SF   W++A + 
Sbjct  180  QAGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGC  239

Query  241  CDEEKRCIREDIAQSVVQRCQQAQDAVVTELTQKREKTPPPLCFDLGMLQQVASRQWGMG  300
             D+  RC+++  AQ   +R + A  A V  +T  R + +PPL FDLG LQ+V SRQ +++
Sbjct  240  SDDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALD  299

Query  301  AGQVLTIAQSLYEIHKATTYPRTDCGYLPVSMREDIPAVFTALTRTDPAMNAIISQLDAS  360
              + L IAQ+LYE HKATTYPR+D GYLP SM  ++PAV++A+  TDP++ +++ QLD +
Sbjct  300  VQETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRT  359

Query  361  TLSRVWNDSQITAHHAIIPTRHTFDMTKLTADELKIYQLIRHYYLAQFLPVQETDVTDVT  420
              SR WNDS+++AHH+IIPT +  +++ ++   L +Y+LIR  YLAQFLP  E D T   
Sbjct  360  QRSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQ  419

Query  421  FTIGGQVFQAKGRVSVVTGWKTLFADEKQVQEQDDNTA----LPALKKEEICPVLRAEIQ  476
            +  GGQ +QA G+  ++ GW  ++A+    + +++  +    LPAL+    C V + +++
Sbjct  420  LLCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLSCQVNHVDLK  479

Query  477  PRQTRPPAPFTEGTLIAAMKNAAAFIHDPQLKKVLRENAGLGTEATRAGIIEALFNRQLL  536
            + +T+PP P+T+G LI AMK  A ++ DP+LK+ L+E +G+GTEATRA+II +L++R  L
Sbjct  480  ALKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERGYL  539

Query  537  ARKKKNLHATPLAQELIAGLPDVLTHPGMTALWEQSLDDIARGRATLDGFMQKQAQWLAH  596
             +K + ++A+  A  LI ++P  +T+PG TA+WEQ+LD I  G  TL+ F+ KQ+ W+++
Sbjct  540  LKKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWITQ  599

Query  597  LVEKGKTQPIRFTLPKTPACPRCGGPMQKRAGKTTPFWGCTRYPACKGML---NANAVTG  653
            LV++ ++  + + LP  PACP CG++ ++R+GKT PFW+C RYP CKG L   N+   ++
Sbjct  600  LVQQYRAATLAIKLPEGPACPLCGSATRQRTGKTGPFWSCCRYPDCKGTLPVQNGRQASA  659

Query  654  SRKTRR  659
             R T R
Sbjct  660  KRSTSR  665

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  536 bits (2022),  Expect = 2e-153, Method: Compositional matrix adjust.
 Identities = 310/666 (47%), Positives = 472/666 (71%), Gaps = 8/666 (1%)

Query  1    MPLYLCEKPSQARDIARVLGVKQRGQGYLFGDSITVTWAIGHLLEMAAPEHYGEQFGPPW  60
            M L+LCEKPSQ++DIARVLG  QRG G   G +  VTW IGHL+E A+PE YGEQ+   W
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQY-KRW  59

Query  61   RMEPLPVLPVQWQWTVKKETADQFAVIRQLLKQADEVIIATDADREGEVIARELLEYCRF  120
             +E LP++P +W+   K  TA Q+ +++QL+ QA E++IATDADREGE+IARE+++ C +
Sbjct  60   SLEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGY  119

Query  121  TGPVRRLWLSALDETSIRQALAAILLGEQTEPLWQAGLGRARADWLMGINLTRLYTLKAQ  180
             GP++RLWLSAL+++SIR+AL+A+  + ++ PL  A+L+R+RADWL+G+NL+RL+TL ++
Sbjct  120  RGPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGR  179

Query  181  AQGFGEVLSIGRVQTPTLALVVNRDNDIARFEPKPYWQVMAALQKDDISFRVKWLPAPDD  240
              G++ VLS+GRVQTPTLALVV RD +IARF + P+W +  +L  ++ SF   W++A + 
Sbjct  180  QAGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGC  239

Query  241  CDEEKRCIREDIAQSVVQRCQQAQDAVVTELTQKREKTPPPLCFDLGMLQQVASRQWGMG  300
             D+  RC+++  AQ   +R + A  A V  +T  R + +PPL FDLG LQ+V SRQ +++
Sbjct  240  SDDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALD  299

Query  301  AGQVLTIAQSLYEIHKATTYPRTDCGYLPVSMREDIPAVFTALTRTDPAMNAIISQLDAS  360
              + L IAQ+LYE HKATTYPR+D GYLP SM  ++PAV++A+  TDP++ +++ QLD +
Sbjct  300  VQETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRT  359

Query  361  TLSRVWNDSQITAHHAIIPTRHTFDMTKLTADELKIYQLIRHYYLAQFLPVQETDVTDVT  420
              SR WNDS+++AHH+IIPT +  +++ ++   L +Y+LIR  YLAQFLP  E D T   
Sbjct  360  QRSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQ  419

Query  421  FTIGGQVFQAKGRVSVVTGWKTLFADEKQVQEQDDNTA----LPALKKEEICPVLRAEIQ  476
            +  GGQ +QA G+  ++ GW  ++A+    + +++  +    LPAL+    C V + +++
Sbjct  420  LLCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLSCQVNHVDLK  479

Query  477  PRQTRPPAPFTEGTLIAAMKNAAAFIHDPQLKKVLRENAGLGTEATRAGIIEALFNRQLL  536
            + +T+PP P+T+G LI AMK  A ++ DP+LK+ L+E +G+GTEATRA+II +L++R  L
Sbjct  480  ALKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERGYL  539

Query  537  ARKKKNLHATPLAQELIAGLPDVLTHPGMTALWEQSLDDIARGRATLDGFMQKQAQWLAH  596
             +K + ++A+  A  LI ++P  +T+PG TA+WEQ+LD I  G  TL+ F+ KQ+ W+++
Sbjct  540  LKKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWITQ  599

Query  597  LVEKGKTQPIRFTLPKTPACPRCGGPMQKRAGKTTPFWGCTRYPACKGML---NANAVTG  653
            LV++ ++  + + LP  PACP CG++ ++R+GKT PFW+C RYP CKG L   N+   ++
Sbjct  600  LVQQYRAATLAIKLPEGPACPLCGSATRQRTGKTGPFWSCCRYPDCKGTLPVQNGRQASA  659

Query  654  SRKTRR  659
             R T R
Sbjct  660  KRSTSR  665

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  532 bits (2007),  Expect = 2e-152, Method: Compositional matrix adjust.
 Identities = 324/649 (50%), Positives = 463/649 (72%), Gaps = 8/649 (1%)

Query  6    MKLFLCEKPSQGNDIAKVLGATKRGEGCLSTPDGQLTVTWGIGHLVEQFNPEEYDPAFKK  65
            M+LFLCEKPSQG+DIA+VLGA +RG GC + ++    VTW IGHL+E   PE Y+  +K+
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGT--VVTWCIGHLIEAAPPEAYGEQYKR  58

Query  66   WAFETLPIIPGKWGLSPKKETKKQFNVVMKLIKQAKLVVIATDIDREGETIARELLDLAG  125
            W++E LPIIP +W + PK  T  Q+++V +L+ QA  +VIATD DREGE IARE++DL G
Sbjct  59   WSLEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCG  118

Query  126  FRGQIKRLWLSALDDTSIRKALGALKNNEETLPLYYAGLARSRADWLIGMNFSRLYTLLA  185
            +RG I+RLWLSAL+D+SIRKALGALK + E+LPLY A+LARSRADWL+GMN+SRL+TLL+
Sbjct  119  YRGPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLG  178

Query  186  QQQGYQGKPLSVGRVQTPTLSLVVNRDREIKNFIPKQHFALQVMLSDGNQHFATQYVIPE  245
            +Q GY+G  LSVGRVQTPTL+LVV RDREI  F++    +++V LS G + F +  + ++
Sbjct  179  RQAGYDG-VLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAAD  237

Query  246  QYCDPDGLCLSAQVIQAANQQIRQFGQAKVESVETKRERQNAPLCFALSDLQSEANRLYG  305
               D  G CL     Q A +++R  G A+V +V T R R+ +PL F L+ LQ   +R  +
Sbjct  238  GCSDDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLA  297

Query  306  LGAQRVLDIAQSLYETHKATTYPRTDCGYLPESQFAEAPQIIQCLLQSDNRLHPLAGMLN  365
            L+ Q  LDIAQ+LYETHKATTYPR+D GYLPES +AE P ++  +L +D  L+PL   L+
Sbjct  298  LDVQETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLD  357

Query  366  LNQKSRVWNDKKITAHHGIIPTMIKADISKMSDEELKLYDLIRRRYLAQFLPVSETDKTQ  425
              Q+SR WND K++AHHGIIPT+  A+++ +SD  L +Y LIR +YLAQFLP  E D+T 
Sbjct  358  RTQRSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTT  417

Query  426  IILKCGQHILSARGNVLIAPGWKILFGKSLDEDDDA-----PQALPTLKQGQICQISDSE  480
              L CG + L A G+ +I PGW  +++ +  ++ D+     +Q LP+L++G  CQ+++ +
Sbjct  418  AQLLCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLSCQVNHVD  477

Query  481  IKTLQTSPPNHFTEGTLLTAMKNAARFVTDERLKQRLRETEGLGTEATRAGTIQglidkg  540
            +K+L+T PP+ +T+G L+ AMK  A++VTD RLKQ+L+ET G+GTEATRA+ I+GL+++G
Sbjct  478  LKALKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERG  537

Query  541  flkkkgksllATDEAMTLIDNLPQMLKDPGLTALWEQALNQIAERTLSLEVFMQKQEVFV  600
            +L KKG+++ A+D A  LID +P  + DPG TA+WEQAL+ I    ++LE F+ KQ   +
Sbjct  538  YLLKKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWI  597

Query  601  RHLMADCLKKGMSLGNIEIRKCPKCGAPMIKRNGKNGAFFGCSAYPNCQ  649
             +L+ +     +++   E   CP CG++  +R GK G+F +C  YP+C+
Sbjct  598  TQLVQQYRAATLAIKLPEGPACPLCGSATRQRTGKTGPFWSCCRYPDCK  646

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  531 bits (2005),  Expect = 3e-152, Method: Compositional matrix adjust.
 Identities = 324/649 (50%), Positives = 463/649 (72%), Gaps = 8/649 (1%)

Query  1    MKLFLCEKPSQGNDIAKVLGATKRGEGCLSTPDGQLTVTWGIGHLVEQFNPEEYDPAFKK  60
            M+LFLCEKPSQG+DIA+VLGA +RG GC + ++    VTW IGHL+E   PE Y+  +K+
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGT--VVTWCIGHLIEAAPPEAYGEQYKR  58

Query  61   WAFETLPIIPGKWGLSPKKETKKQFNVVMKLIKQAKLVVIATDIDREGETIARELLDLAG  120
            W++E LPIIP +W + PK  T  Q+++V +L+ QA  +VIATD DREGE IARE++DL G
Sbjct  59   WSLEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCG  118

Query  121  FRGQIKRLWLSALDDTSIRKALGALKNNEETLPLYYAGLARSRADWLIGMNFSRLYTLLA  180
            +RG I+RLWLSAL+D+SIRKALGALK + E+LPLY A+LARSRADWL+GMN+SRL+TLL+
Sbjct  119  YRGPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLG  178

Query  181  QQQGYQGKPLSVGRVQTPTLSLVVNRDREIKNFIPKQHFALQVMLSDGNQHFATQYVIPE  240
            +Q GY+G  LSVGRVQTPTL+LVV RDREI  F++    +++V LS G + F +  + ++
Sbjct  179  RQAGYDG-VLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAAD  237

Query  241  QYCDPDGLCLSAQVIQAANQQIRQFGQAKVESVETKRERQNAPLCFALSDLQSEANRLYG  300
               D  G CL     Q A +++R  G A+V +V T R R+ +PL F L+ LQ   +R  +
Sbjct  238  GCSDDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLA  297

Query  301  LGAQRVLDIAQSLYETHKATTYPRTDCGYLPESQFAEAPQIIQCLLQSDNRLHPLAGMLN  360
            L+ Q  LDIAQ+LYETHKATTYPR+D GYLPES +AE P ++  +L +D  L+PL   L+
Sbjct  298  LDVQETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLD  357

Query  361  LNQKSRVWNDKKITAHHGIIPTMIKADISKMSDEELKLYDLIRRRYLAQFLPVSETDKTQ  420
              Q+SR WND K++AHHGIIPT+  A+++ +SD  L +Y LIR +YLAQFLP  E D+T 
Sbjct  358  RTQRSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTT  417

Query  421  IILKCGQHILSARGNVLIAPGWKILFGKSLDEDDDA-----PQALPTLKQGQICQISDSE  475
              L CG + L A G+ +I PGW  +++ +  ++ D+     +Q LP+L++G  CQ+++ +
Sbjct  418  AQLLCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLSCQVNHVD  477

Query  476  IKTLQTSPPNHFTEGTLLTAMKNAARFVTDERLKQRLRETEGLGTEATRAGTIQglidkg  535
            +K+L+T PP+ +T+G L+ AMK  A++VTD RLKQ+L+ET G+GTEATRA+ I+GL+++G
Sbjct  478  LKALKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERG  537

Query  536  flkkkgksllATDEAMTLIDNLPQMLKDPGLTALWEQALNQIAERTLSLEVFMQKQEVFV  595
            +L KKG+++ A+D A  LID +P  + DPG TA+WEQAL+ I    ++LE F+ KQ   +
Sbjct  538  YLLKKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWI  597

Query  596  RHLMADCLKKGMSLGNIEIRKCPKCGAPMIKRNGKNGAFFGCSAYPNCQ  644
             +L+ +     +++   E   CP CG++  +R GK G+F +C  YP+C+
Sbjct  598  TQLVQQYRAATLAIKLPEGPACPLCGSATRQRTGKTGPFWSCCRYPDCK  646

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  531 bits (2005),  Expect = 3e-152, Method: Compositional matrix adjust.
 Identities = 324/649 (50%), Positives = 463/649 (72%), Gaps = 8/649 (1%)

Query  1    MKLFLCEKPSQGNDIAKVLGATKRGEGCLSTPDGQLTVTWGIGHLVEQFNPEEYDPAFKK  60
            M+LFLCEKPSQG+DIA+VLGA +RG GC + ++    VTW IGHL+E   PE Y+  +K+
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGT--VVTWCIGHLIEAAPPEAYGEQYKR  58

Query  61   WAFETLPIIPGKWGLSPKKETKKQFNVVMKLIKQAKLVVIATDIDREGETIARELLDLAG  120
            W++E LPIIP +W + PK  T  Q+++V +L+ QA  +VIATD DREGE IARE++DL G
Sbjct  59   WSLEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCG  118

Query  121  FRGQIKRLWLSALDDTSIRKALGALKNNEETLPLYYAGLARSRADWLIGMNFSRLYTLLA  180
            +RG I+RLWLSAL+D+SIRKALGALK + E+LPLY A+LARSRADWL+GMN+SRL+TLL+
Sbjct  119  YRGPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLG  178

Query  181  QQQGYQGKPLSVGRVQTPTLSLVVNRDREIKNFIPKQHFALQVMLSDGNQHFATQYVIPE  240
            +Q GY+G  LSVGRVQTPTL+LVV RDREI  F++    +++V LS G + F +  + ++
Sbjct  179  RQAGYDG-VLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAAD  237

Query  241  QYCDPDGLCLSAQVIQAANQQIRQFGQAKVESVETKRERQNAPLCFALSDLQSEANRLYG  300
               D  G CL     Q A +++R  G A+V +V T R R+ +PL F L+ LQ   +R  +
Sbjct  238  GCSDDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLA  297

Query  301  LGAQRVLDIAQSLYETHKATTYPRTDCGYLPESQFAEAPQIIQCLLQSDNRLHPLAGMLN  360
            L+ Q  LDIAQ+LYETHKATTYPR+D GYLPES +AE P ++  +L +D  L+PL   L+
Sbjct  298  LDVQETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLD  357

Query  361  LNQKSRVWNDKKITAHHGIIPTMIKADISKMSDEELKLYDLIRRRYLAQFLPVSETDKTQ  420
              Q+SR WND K++AHHGIIPT+  A+++ +SD  L +Y LIR +YLAQFLP  E D+T 
Sbjct  358  RTQRSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTT  417

Query  421  IILKCGQHILSARGNVLIAPGWKILFGKSLDEDDDA-----PQALPTLKQGQICQISDSE  475
              L CG + L A G+ +I PGW  +++ +  ++ D+     +Q LP+L++G  CQ+++ +
Sbjct  418  AQLLCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLSCQVNHVD  477

Query  476  IKTLQTSPPNHFTEGTLLTAMKNAARFVTDERLKQRLRETEGLGTEATRAGTIQglidkg  535
            +K+L+T PP+ +T+G L+ AMK  A++VTD RLKQ+L+ET G+GTEATRA+ I+GL+++G
Sbjct  478  LKALKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERG  537

Query  536  flkkkgksllATDEAMTLIDNLPQMLKDPGLTALWEQALNQIAERTLSLEVFMQKQEVFV  595
            +L KKG+++ A+D A  LID +P  + DPG TA+WEQAL+ I    ++LE F+ KQ   +
Sbjct  538  YLLKKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWI  597

Query  596  RHLMADCLKKGMSLGNIEIRKCPKCGAPMIKRNGKNGAFFGCSAYPNCQ  644
             +L+ +     +++   E   CP CG++  +R GK G+F +C  YP+C+
Sbjct  598  TQLVQQYRAATLAIKLPEGPACPLCGSATRQRTGKTGPFWSCCRYPDCK  646

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  528 bits (1993),  Expect = 3e-151, Method: Compositional matrix adjust.
 Identities = 318/603 (53%), Positives = 454/603 (76%), Gaps = 6/603 (0%)

Query  1    MQLYLCEKPSQARDIARVLDARNRSDGYLHNATVTITWCFGHLLSMAAPEDYDPALKHWR  60
            M+L+LCEKPSQ++DIARVL+A +R+ G  + A   +TWC+GHL+  A+PE Y+   K+W 
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQYKRWS  60

Query  61   AEHLPFIPPAWRLVIRPEVRKQFRIIEKLLKQADAVVIATDADREGETIAREILEQCRWR  120
             E+LP+IP  WR+  ++    Q++I+ +L+ QA  +VIATDADREGE IAREI++ C  R
Sbjct  61   LEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGYR  120

Query  121  GPVQRLWLSALDDASIHKALAAMRSGDSTYPLYQAGLARARADWLVGINMTRACTLMNRR  180
            GP+QRLWLSAL+DASI+KAL+A++++  + PLY A+LAR+RADWLVG+N++R  TL+ R+
Sbjct  121  GPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGRQ  180

Query  181  --HKGVLSVGRVQTPTLRLVVERDREISRFTPRPWWRVDARLHAEGTTFLAQWQPDGVYC  238
                GVLSVGRVQTPTL LVV RDREI+RF + P W ++  L + G +FLA W + +   
Sbjct  181  AGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGCS  240

Query  239  DDEGRCIRESAAREATASLQQAGTTLVLDVTTRREKTPPPLAFTLSALQQVCSKQWGMGA  298
            DD GRC+++++A++A+  L+ AG++ V+ VTT R + +PPL+F L++LQ+VCS+Q +++ 
Sbjct  241  DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALDV  300

Query  299  QEVLDIAQRLYETHKATTYPRTDCGWLPLSMHTEAPQVLAALVASDISLQPLATQLNLQQ  358
            QE LDIAQ LYETHKATTYPR+D G LP SM +E P VLAA++++D SL+PL  QL+  Q
Sbjct  301  QETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRTQ  360

Query  359  HSRLWDDSKITAHHGIIPTRKTVDLTQMNDSERKVYGLVRSHFLAQFLSDHEVDKTDLRL  418
            +SR W+DSK++AHHGIIPT    +L+ ++D    VY L+R+H+LAQFL++ E D+T  +L
Sbjct  361  RSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQL  420

Query  419  NCAGETLAARGSVVIVSGWQQLFLREMATHSPEE----TQSLPVLQQGQTCQVEQVDVRA  474
             C+G+TL A G  VI++GW+Q++    A ++  E    +Q LP L++G +CQV++VD++A
Sbjct  421  LCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLSCQVNHVDLKA  480

Query  475  RQTQPPEHYTEGTLIAAMKNAARFVSDERLKQRLKENAGIGTEATRAGIIQTLLKRGYLI  534
             +TQPP  YT+G LI AMK  A++V+D RLKQ+LKE +GIGTEATRA+II+ LL RGYL+
Sbjct  481  LKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERGYLL  540

Query  535  KQRRFLLATDTASALIDALPEKLKDPGTTALWEQMLDDIATGKMGLEAFLVQQQETVTAL  594
            K+ R + A+D+A+ LIDA+P  + DPGTTA+WEQ LD I +G M LE+F+ +Q   +T L
Sbjct  541  KKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWITQL  600

Query  595  TAQ  597
              Q
Sbjct  601  VQQ  603

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  528 bits (1993),  Expect = 3e-151, Method: Compositional matrix adjust.
 Identities = 322/649 (50%), Positives = 463/649 (72%), Gaps = 8/649 (1%)

Query  1    MKLFLCEKPSQGNDIAKILGATKRGEGCLSTPDGQLTVTWGIGHLVEQFNPEEYDPAFKK  60
            M+LFLCEKPSQG+DIA++LGA +RG GC + ++    VTW IGHL+E   PE Y+  +K+
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGT--VVTWCIGHLIEAAPPEAYGEQYKR  58

Query  61   WAFETLPIIPGKWGLSPKKETKKQFNVVMKLIKQAKLVVIATDIDREGETIARELLDLAG  120
            W++E LPIIP +W + PK  T  Q+++V +L+ QA  +VIATD DREGE IARE++DL G
Sbjct  59   WSLEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCG  118

Query  121  FRGQIKRLWLSALDDASIRKALGALKDNEETLPLYYAGLARSRADWLIGMNFSRIYTLLA  180
            +RG I+RLWLSAL+DASIRKALGALK + E+LPLY A+LARSRADWL+GMN+SR++TLL+
Sbjct  119  YRGPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLG  178

Query  181  QQQGYQGKPLSVGRVQTPTLSLVVNRDREIKNFIPKQHFALQVMLSDGNQHFATQYVIPE  240
            +Q GY+G  LSVGRVQTPTL+LVV RDREI  F++    +++V LS G + F +  + ++
Sbjct  179  RQAGYDG-VLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAAD  237

Query  241  QYCDPDGLCLSAQVIQAANQQIRQLGQAKMESVETKRERQNAPLCFALSDLQSEANRLYG  300
               D  G CL     Q A +++R  G A++ +V T R R+ +PL F L+ LQ   +R  +
Sbjct  238  GCSDDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLA  297

Query  301  LGAQRVLDIAQSLYETHKATTYPRTDCGYLPESQFAEAPKIIQCLLQSDNRLQPLAGMLN  360
            L+ Q  LDIAQ+LYETHKATTYPR+D GYLPES +AE P ++  +L +D  L+PL   L+
Sbjct  298  LDVQETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLD  357

Query  361  LNQKSRVWNDKKITAHHGIIPTMIKADISKMSDEELKLYDLIRRRYLAQFLPVSETDKTQ  420
              Q+SR WND K++AHHGIIPT+  A+++ +SD  L +Y LIR +YLAQFLP  E D+T 
Sbjct  358  RTQRSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTT  417

Query  421  IILKCGQHILSARGNVLIAPGWKILFGKSLDEDDDA-----PQALPTLKQGQICQISDSE  475
              L CG + L A G+ +I PGW  +++ +  ++ D+     +Q LP+L++G  CQ+++ +
Sbjct  418  AQLLCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLSCQVNHVD  477

Query  476  IKTLQTSPPNHFTEGTLLTAMKNAARFVTDERLKQRLRETEGLGTEATRAGTIQglidkg  535
            +K+L+T PP+ +T+G L+ AMK  A++VTD RLKQ+L+ET G+GTEATRA+ I+GL+++G
Sbjct  478  LKALKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERG  537

Query  536  flkkkgksllATDEAMTLIDNLPQMLKDPGLTALWEQALNQIAERTLSLEVFMQKQEVFV  595
            +L KKG+++ A+D A  LID +P  + DPG TA+WEQAL+ I    ++LE F+ KQ   +
Sbjct  538  YLLKKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWI  597

Query  596  RHLMADCLKKGMSLGNIEIRKCPKCGAPMIKRNGKNGAFLGCSAYPNCQ  644
             +L+ +     +++   E   CP CG++  +R GK G+F +C  YP+C+
Sbjct  598  TQLVQQYRAATLAIKLPEGPACPLCGSATRQRTGKTGPFWSCCRYPDCK  646

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  527 bits (1989),  Expect = 7e-151, Method: Compositional matrix adjust.
 Identities = 318/650 (49%), Positives = 474/650 (73%), Gaps = 6/650 (0%)

Query  1    MKLFICEKPSQARDLAGVLGATSKGEGLLATADKSIIVTWGFGHLVEQYQPEDYDEAWKR  60
            M+LF+CEKPSQ++D+A VLGA  +G G     + + +VTW +GHL+E   PE Y+E  KR
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSG--CYNGAGTVVTWCIGHLIEAAPPEAYGEQYKR  58

Query  61   WAFETLPIIPAQWKMTPKKESKKQYSVVIGLIKKATSVVIATDADREGEMIARELLDLAG  120
            W++E LPIIP +W++ PK  +  Q  +V  L+ +A+ +VIATDADREGEMIARE++DL G
Sbjct  59   WSLEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCG  118

Query  121  YRGQIQRCWLSALDDASIRKALQTLKSGKETEALYYAGMGRSRSDWLIGMNFSRLFTLMA  180
            YRG IQR WLSAL+DASIRKAL +LK++ E+ +LY A+++RSR+DWL+GMN+SRLFTL++
Sbjct  119  YRGPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLG  178

Query  181  QAKGYSGKPLSVGRVQSPTLTLVVNRDREIANFVPKSHYALAVQLTTTSGETFVAGLAVP  240
            +  GY G  LSVGRVQ+PTL+LVV RDREIA FV+ +  ++ V L+T +G++F+A    +
Sbjct  179  RQAGYDG-VLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLST-GGHSFLATWIAA  236

Query  241  EQYLDESGLCLDSRVIQQAEAQIKQTGLAkvvtvetkrekkSPPLLYALSDLQGECNRLF  300
            +   D++G CL+    QQA  +++ +G A+VV+V T R + +PPL + L+ LQ+ C+R +
Sbjct  237  DGCSDDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQL  296

Query  301  GFGAQQVLDIAQSLYEEHKITTYPRTDCGYLPESQFSDVPNVIRSLVASDSGLQTLLPKL  360
            +++ Q+ LDIAQ+LYE HK TTYPR+D GYLPES +++VP V+ +++++D++L+ LL +L
Sbjct  297  ALDVQETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQL  356

Query  361  NLRQKSRAWDDKKITAHHGIIPTIKKADLSKLSEEEMKVYDLIRRRYLAQFLPHLEMDKT  420
            +  Q+SRAW+D K++AHHGIIPT+  A+L+ +S+  + VY LIR +YLAQFLPH E D+T
Sbjct  357  DRTQRSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRT  416

Query  421  VATLQSSGHTLVARGNVIVAQGWR-ILFGKNVDEETGNDDEK-QGLPVLTKNQQCNVTHS  478
             A L  +G+TL A G+ ++  GW+ +L G + D+  G+   + Q LP L     C+V H 
Sbjct  417  TAQLLCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLSCQVNHV  476

Query  479  EVRTLQTKPPAHYTEGTLLDAMKNAARFVTDPRLKQRLRETEGLGTEATRAGLIQGLIDK  538
            ++++L+T+PP  YT+G L+ AMK  A++VTDPRLKQ+L+ET G+GTEATRA++I+GL+++
Sbjct  477  DLKALKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLER  536

Query  539  GFllkkkkslvasaeavalIDSLPDLLKNPGLTALWEQALNQIAEGSMTLDAFMQKQEAF  598
            G+LLKK +++ AS  A  LID++P  + +PG TA+WEQAL+ I  G MTL++F+ KQ + 
Sbjct  537  GYLLKKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTW  596

Query  599  VKQLIGSCMQQGMSLGNIEIRKCSECGKPMRKINHAKGTFWGCTGYPDCQ  648
            + QL+       +++   E   C+ CG + R+     G FW+C  YPDC+
Sbjct  597  ITQLVQQYRAATLAIKLPEGPACPLCGSATRQRTGKTGPFWSCCRYPDCK  646

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  527 bits (1989),  Expect = 7e-151, Method: Compositional matrix adjust.
 Identities = 318/650 (49%), Positives = 474/650 (73%), Gaps = 6/650 (0%)

Query  1    MKLFICEKPSQARDLAGVLGATSKGEGLLATADKSIIVTWGFGHLVEQYQPEDYDEAWKR  60
            M+LF+CEKPSQ++D+A VLGA  +G G     + + +VTW +GHL+E   PE Y+E  KR
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSG--CYNGAGTVVTWCIGHLIEAAPPEAYGEQYKR  58

Query  61   WAFETLPIIPAQWKMTPKKESKKQYSVVIGLIKKATSVVIATDADREGEMIARELLDLAG  120
            W++E LPIIP +W++ PK  +  Q  +V  L+ +A+ +VIATDADREGEMIARE++DL G
Sbjct  59   WSLEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCG  118

Query  121  YRGQIQRCWLSALDDASIRKALQTLKSGKETEALYYAGMGRSRSDWLIGMNFSRLFTLMA  180
            YRG IQR WLSAL+DASIRKAL +LK++ E+ +LY A+++RSR+DWL+GMN+SRLFTL++
Sbjct  119  YRGPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLG  178

Query  181  QAKGYSGKPLSVGRVQSPTLTLVVNRDREIANFVPKSHYALAVQLTTTSGETFVAGLAVP  240
            +  GY G  LSVGRVQ+PTL+LVV RDREIA FV+ +  ++ V L+T +G++F+A    +
Sbjct  179  RQAGYDG-VLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLST-GGHSFLATWIAA  236

Query  241  EQYLDESGLCLDSRVIQQAEAQIKQTGLAkvvtvetkrekkSPPLLYALSDLQGECNRLF  300
            +   D++G CL+    QQA  +++ +G A+VV+V T R + +PPL + L+ LQ+ C+R +
Sbjct  237  DGCSDDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQL  296

Query  301  GFGAQQVLDIAQSLYEEHKITTYPRTDCGYLPESQFSDVPNVIRSLVASDSGLQTLLPKL  360
            +++ Q+ LDIAQ+LYE HK TTYPR+D GYLPES +++VP V+ +++++D++L+ LL +L
Sbjct  297  ALDVQETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQL  356

Query  361  NLRQKSRAWDDKKITAHHGIIPTIKKADLSKLSEEEMKVYDLIRRRYLAQFLPHLEMDKT  420
            +  Q+SRAW+D K++AHHGIIPT+  A+L+ +S+  + VY LIR +YLAQFLPH E D+T
Sbjct  357  DRTQRSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRT  416

Query  421  VATLQSSGHTLVARGNVIVAQGWR-ILFGKNVDEETGNDDEK-QGLPVLTKNQQCNVTHS  478
             A L  +G+TL A G+ ++  GW+ +L G + D+  G+   + Q LP L     C+V H 
Sbjct  417  TAQLLCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLSCQVNHV  476

Query  479  EVRTLQTKPPAHYTEGTLLDAMKNAARFVTDPRLKQRLRETEGLGTEATRAGLIQGLIDK  538
            ++++L+T+PP  YT+G L+ AMK  A++VTDPRLKQ+L+ET G+GTEATRA++I+GL+++
Sbjct  477  DLKALKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLER  536

Query  539  GFllkkkkslvasaeavalIDSLPDLLKNPGLTALWEQALNQIAEGSMTLDAFMQKQEAF  598
            G+LLKK +++ AS  A  LID++P  + +PG TA+WEQAL+ I  G MTL++F+ KQ + 
Sbjct  537  GYLLKKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTW  596

Query  599  VKQLIGSCMQQGMSLGNIEIRKCSECGKPMRKINHAKGTFWGCTGYPDCQ  648
            + QL+       +++   E   C+ CG + R+     G FW+C  YPDC+
Sbjct  597  ITQLVQQYRAATLAIKLPEGPACPLCGSATRQRTGKTGPFWSCCRYPDCK  646

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  527 bits (1989),  Expect = 7e-151, Method: Compositional matrix adjust.
 Identities = 318/650 (49%), Positives = 474/650 (73%), Gaps = 6/650 (0%)

Query  1    MKLFICEKPSQARDLAGVLGATSKGEGLLATADKSIIVTWGFGHLVEQYQPEDYDEAWKR  60
            M+LF+CEKPSQ++D+A VLGA  +G G     + + +VTW +GHL+E   PE Y+E  KR
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSG--CYNGAGTVVTWCIGHLIEAAPPEAYGEQYKR  58

Query  61   WAFETLPIIPAQWKMTPKKESKKQYSVVIGLIKKATSVVIATDADREGEMIARELLDLAG  120
            W++E LPIIP +W++ PK  +  Q  +V  L+ +A+ +VIATDADREGEMIARE++DL G
Sbjct  59   WSLEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCG  118

Query  121  YRGQIQRCWLSALDDASIRKALQTLKSGKETEALYYAGMGRSRSDWLIGMNFSRLFTLMA  180
            YRG IQR WLSAL+DASIRKAL +LK++ E+ +LY A+++RSR+DWL+GMN+SRLFTL++
Sbjct  119  YRGPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLG  178

Query  181  QAKGYSGKPLSVGRVQSPTLTLVVNRDREIANFVPKSHYALAVQLTTTSGETFVAGLAVP  240
            +  GY G  LSVGRVQ+PTL+LVV RDREIA FV+ +  ++ V L+T +G++F+A    +
Sbjct  179  RQAGYDG-VLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLST-GGHSFLATWIAA  236

Query  241  EQYLDESGLCLDSRVIQQAEAQIKQTGLAkvvtvetkrekkSPPLLYALSDLQGECNRLF  300
            +   D++G CL+    QQA  +++ +G A+VV+V T R + +PPL + L+ LQ+ C+R +
Sbjct  237  DGCSDDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQL  296

Query  301  GFGAQQVLDIAQSLYEEHKITTYPRTDCGYLPESQFSDVPNVIRSLVASDSGLQTLLPKL  360
            +++ Q+ LDIAQ+LYE HK TTYPR+D GYLPES +++VP V+ +++++D++L+ LL +L
Sbjct  297  ALDVQETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQL  356

Query  361  NLRQKSRAWDDKKITAHHGIIPTIKKADLSKLSEEEMKVYDLIRRRYLAQFLPHLEMDKT  420
            +  Q+SRAW+D K++AHHGIIPT+  A+L+ +S+  + VY LIR +YLAQFLPH E D+T
Sbjct  357  DRTQRSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRT  416

Query  421  VATLQSSGHTLVARGNVIVAQGWR-ILFGKNVDEETGNDDEK-QGLPVLTKNQQCNVTHS  478
             A L  +G+TL A G+ ++  GW+ +L G + D+  G+   + Q LP L     C+V H 
Sbjct  417  TAQLLCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLSCQVNHV  476

Query  479  EVRTLQTKPPAHYTEGTLLDAMKNAARFVTDPRLKQRLRETEGLGTEATRAGLIQGLIDK  538
            ++++L+T+PP  YT+G L+ AMK  A++VTDPRLKQ+L+ET G+GTEATRA++I+GL+++
Sbjct  477  DLKALKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLER  536

Query  539  GFllkkkkslvasaeavalIDSLPDLLKNPGLTALWEQALNQIAEGSMTLDAFMQKQEAF  598
            G+LLKK +++ AS  A  LID++P  + +PG TA+WEQAL+ I  G MTL++F+ KQ + 
Sbjct  537  GYLLKKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTW  596

Query  599  VKQLIGSCMQQGMSLGNIEIRKCSECGKPMRKINHAKGTFWGCTGYPDCQ  648
            + QL+       +++   E   C+ CG + R+     G FW+C  YPDC+
Sbjct  597  ITQLVQQYRAATLAIKLPEGPACPLCGSATRQRTGKTGPFWSCCRYPDCK  646

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  525 bits (1980),  Expect = 3e-150, Method: Compositional matrix adjust.
 Identities = 312/667 (47%), Positives = 476/667 (72%), Gaps = 10/667 (1%)

Query  1    MPLYLCEKPSQARDIARVLGVKQRGQGYLFGDSIIVTWAIGHLLEMAAPEHYGEQFGPPW  60
            M L+LCEKPSQ++DIARVLG  QRG G   G + +VTW IGHL+E A+PE YGEQ+   W
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQY-KRW  59

Query  61   RMEPLPVLPAQWQWTVKKETADQFAVIRQLLKQADEVIIATDADREGEVIARELLEYCRF  120
             +E LP++P +W+   K  TA Q+ +++QL+ QA E++IATDADREGE+IARE+++ C +
Sbjct  60   SLEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGY  119

Query  121  TGPVRRLWLSALDETSIRQALAAILPGEKTESLWQAGLGRARADWLMGINLTRLYTLKAQ  180
             GP++RLWLSAL+++SIR+AL+A+ P+  + +L  A+L+R+RADWL+G+NL+RL+TL ++
Sbjct  120  RGPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGR  179

Query  181  AQGFGEVLSIGRVQTPTLALVVNRDNDIARFEPKPYWQVVATLQKDGIGFRVKWLPAPDD  240
              G++ VLS+GRVQTPTLALVV RD +IARF + P+W +   L  +G +F   W++A + 
Sbjct  180  QAGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGC  239

Query  241  CDEEKRCIKEDIAHSVVQCCQEAQNAVVTELTQKREKTPPPLCFDLGMLQQVASRQWGMG  300
             D+  RC+++  A+   +  + A +A V  +T  R + +PPL FDLG LQ+V SRQ +++
Sbjct  240  SDDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALD  299

Query  301  AGQVLTIAQSLYEIHKATTYPRTDCGYLPVSMREDIPAVFTALTRTDPAMNAIISQLDAS  360
              + L IAQ+LYE HKATTYPR+D GYLP SM  ++PAV++A+  TDP++ +++ QLD +
Sbjct  300  VQETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRT  359

Query  361  TLSRVWNDSQITAHHAIIPTRHPFDMTKLTADELKVYQLIRQYYLAQFLPAQETDVTDVT  420
              SR WNDS+++AHH+IIPT +P +++ ++   L VY+LIR  YLAQFLP  E D T   
Sbjct  360  QRSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQ  419

Query  421  FTIGGQVFQATGRVSVVTGWKALFADEKQAQDQDGNT-----ALPVLKKAETCPVIRAEI  475
            +  GGQ +QA G+  ++ GW  ++A+  +A++ DG++      LP L+ + +C V + ++
Sbjct  420  LLCGGQTLQAVGKQVIIPGWHQVLAGP-EADNADGEAVPRSQVLPALREGLSCQVNHVDL  478

Query  476  QPRQTRPPAPFTEGTLIAAMKNAAAFIHDPQLKKVLRENAGLGTEATRAGIIEalfkrrl  535
            ++ +T+PP P+T+G LI AMK  A ++ DP+LK+ L+E +G+GTEATRA+II +L+ R  
Sbjct  479  KALKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERGY  538

Query  536  larkkknlhaTQLAQELIAGLPDVLTHPGMTALWEQSLDDIARGRTTLDGFMQKQAQWLA  595
            L +K + ++A++ A  LI ++P  +T+PG TA+WEQ+LD I  G  TL+ F+ KQ+ W++
Sbjct  539  LLKKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWIT  598

Query  596  HLVEKGKTQPIRFTLPKTPACPRCGGPMQKRAGKTTPFWGCTRYPACKGML---NANAVI  652
            +LV++ ++  + + LP  PACP CG++ ++R+GKT PFW+C RYP CKG L   N+    
Sbjct  599  QLVQQYRAATLAIKLPEGPACPLCGSATRQRTGKTGPFWSCCRYPDCKGTLPVQNGRQAS  658

Query  653  GSRKTRR  659
            + R T R
Sbjct  659  AKRSTSR  665

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  522 bits (1968),  Expect = 3e-149, Method: Compositional matrix adjust.
 Identities = 324/603 (54%), Positives = 457/603 (76%), Gaps = 6/603 (0%)

Query  1    MQLYLCEKPSQARDIARVLDARNRSDGYLHNATVTITWCFGHLLSMAAPEDYDPALKHWR  60
            M+L+LCEKPSQ++DIARVL+A +R+ G  + A   +TWC+GHL+  A+PE Y+   K+W 
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQYKRWS  60

Query  61   AEHLPFIPPAWRLVIRPEVRKQFRIIEKLLKQADAVVIATDADREGETIAREILEQCRWR  120
             E+LP+IP  WR+  ++    Q++I+ +L+ QA  +VIATDADREGE IAREI++ C  R
Sbjct  61   LEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGYR  120

Query  121  GPVQRLWLSALDEASIHRALAALRPGDSTFPLYQAGLARARADWLVGINMTRACTLMNLR  180
            GP+QRLWLSAL++ASI++AL+AL+P+  ++PLY A+LAR+RADWLVG+N++R  TL+  +
Sbjct  121  GPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGRQ  180

Query  181  --HKGVLSVGRVQTPTLRLVVERDREIVRFTPRPYWRVDARLHTEGTSFLAQWQPDGAYC  238
                GVLSVGRVQTPTL LVV RDREI RF + P+W ++  L T G SFLA W + ++  
Sbjct  181  AGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGCS  240

Query  239  DDEGRCIRESVARKAAARLQQAGTALVLDVTTRREKTPPPLAFTLSALQQFCSKQWGMGA  298
            DD GRC++++ A++AA RL+ AG+A V+ VTT R + +PPL+F L++LQ+ CS+Q +++ 
Sbjct  241  DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALDV  300

Query  299  QEVLDIAQRLYETHKATTYPRTDCVYLPLSMHAEAPQvlaalvasdaslQPLATQLNLQQ  358
            QE LDIAQ LYETHKATTYPR+D  YLP SM AE P VLAA++++D+SL+PL  QL+  Q
Sbjct  301  QETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRTQ  360

Query  359  RSRLWDDSKITAHHGIIPTRKTVDLTQLNDSERKVYGLVRSHFLAQFLPDHEVDKTDLRL  418
            RSR W+DSK++AHHGIIPT    +L+ ++D    VY L+R+H+LAQFLP+ E D+T  +L
Sbjct  361  RSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQL  420

Query  419  NCAGETLAARGSVVIVSGWRQLFLREMATQSPEE----TQVLPALQQGQTCQVEQVDVRS  474
             C+G+TL A G  VI++GW+Q++    A ++  E    +QVLPAL++G +CQV++VD+++
Sbjct  421  LCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLSCQVNHVDLKA  480

Query  475  RQTQPPEHYTEGTLIAAMKNAARFISDERLKQRLKENAGIGTEATRAGIIQTLLKRGYLI  534
             +TQPP  YT+G LI AMK  A++++D RLKQ+LKE +GIGTEATRA+II+ LL RGYL+
Sbjct  481  LKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERGYLL  540

Query  535  KQRRFLLATDTASTLIDALPEALKDPGTTALWEHMLDEIAMGKMGLEAFLVQQQEAVTAL  594
            K+ R + A+D+A+ LIDA+P A+ DPGTTA+WE+ LD I  G M LE+F+ +Q   +T L
Sbjct  541  KKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWITQL  600

Query  595  TAQ  597
              Q
Sbjct  601  VQQ  603

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  521 bits (1967),  Expect = 4e-149, Method: Compositional matrix adjust.
 Identities = 318/625 (51%), Positives = 447/625 (72%), Gaps = 2/625 (0%)

Query  1    MRLFICEKPSQGRDLAGVLGATRRGDGFLTGSGVTVTWAVGHLLETAPPEAYGQQYGKPW  60
            MRLF+CEKPSQG+D+A VLGA +RG G   G+G  VTW +GHL+E+APPEAYG+QY K W
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQY-KRW  59

Query  61   SLSALPILPAPWRVVVKKETQDQFKVIERLLRQVDDVVIATDADREGEVIARELLEYCRW  120
            SL  LPI+P  WRV  K  T  Q+K++ +L+ Q  ++VIATDADREGE+IARE+++ C  
Sbjct  60   SLEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGY  119

Query  121  EGPVQRLWLSALDELSIRAALQDLRPGQATLGMYHAGLGRARADWLIGMNLSRLYTLRAA  180
             GP+QRLWLSAL++ SIR AL  L+P+  +L +Y A+L+R+RADWL+GMNLSRL+TL + 
Sbjct  120  RGPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGR  179

Query  181  ESGFDGVVSVGRVQTPTLALVVRRDREIAAFVPKPFWQVKALISAGDLTFPAQWVPAKVY  240
            ++G+DGV+SVGRVQTPTLALVV RDREIA FV+ PFW +   +S+G+ +F A W++A   
Sbjct  180  QAGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGC  239

Query  241  TDEEKRCVHQNIAQQVAQLCRQTGHAVVTECDTKREKAAAPLAFSLGSLQQACGRLWDMS  300
            +D+  RC++Q  AQQ A+  R +G A V    T R + A+PL+F LG+LQ+ C+R   + 
Sbjct  240  SDDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALD  299

Query  301  PQQVLDTAQSLYEKHKATTYPRTDCGYLPESMREEISGVLDAIGRTDPECAPVLARLDRT  360
             Q+ LD AQ+LYE HKATTYPR+D GYLPESM  E+++VL A+  TDP   P+L +LDRT
Sbjct  300  VQETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRT  359

Query  361  FVSRIWNDKKITAHHGIIPTRNAFQLSALTETERNVYMLIRRNYLAQFLPLHESDFTRLQ  420
              SR WND K++AHHGIIPT ++ +L+A+++    VY LIR +YLAQFLP  E D T  Q
Sbjct  360  QRSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQ  419

Query  421  FDTGGQLFRATGRTEVIKGW-KVLFENAGDNEVDDGDEADIALPPLAQNDRCAVTGAEVV  479
            +  GGQ ++A G+  +I GW +VL    +DN  +++      LP+L +   C V   ++ 
Sbjct  420  LLCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLSCQVNHVDLK  479

Query  480  QLMTRPPAHYTFATLIGAMMNAAAFVTDVALRKVLKDNAGLGTEATRAGIVEQLLNRHFI  539
             L T+PP  YT + LI AM   A +VTD  L++ LK+ +G+GTEATRA+I+  LL+R ++
Sbjct  480  ALKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERGYL  539

Query  540  VRKGSKIMATELGADVIDALPPQLTEPGMTALWEQALDEVAAGRMSLDDFLQRQTGWTRN  599
            ++KG  + A++ ++ +IDA+P+ +T+PG TA+WEQALD + AG M+L+ F+ +Q+ W  +
Sbjct  540  LKKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWITQ  599

Query  600  LVSQGTQQQVRIRVPPTPACPLCGG  624
            LV Q     + I++P  PACPLCG+
Sbjct  600  LVQQYRAATLAIKLPEGPACPLCGS  624

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  521 bits (1965),  Expect = 5e-149, Method: Compositional matrix adjust.
 Identities = 307/654 (47%), Positives = 467/654 (72%), Gaps = 5/654 (0%)

Query  1    MQLYLCEKPSQARDIARVLGVKQRGQGYLFGDSIIVTWAIGHLLEMAAPEHYGEQFGPPW  60
            M+L+LCEKPSQ++DIARVLG  QRG G   G + +VTW IGHL+E A+PE YGEQ+   W
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQY-KRW  59

Query  61   RMEPLPVLPAQWQWTVKKETADQFAVIRQLLKQADEVIIATDADREGEVIARELLEYCHF  120
             +E LP++P +W+   K  TA Q+ +++QL+ QA E++IATDADREGE+IARE+++ C +
Sbjct  60   SLEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGY  119

Query  121  TGPVRRLWLSALDETSIRQALAAILPGEKTAPLWQAGLGRARADWLTGINLTRLYTLKAQ  180
             GP++RLWLSAL+++SIR+AL+A+ P+  + PL  A+L+R+RADWL G+NL+RL+TL ++
Sbjct  120  RGPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGR  179

Query  181  AQGFGEVLSIGRVQTPTLALVVNRDNDIARFEPKPYWQVMATLQKDDISFRAKWLPAPDD  240
              G++ VLS+GRVQTPTLALVV RD +IARF + P+W +   L  ++ SF A W++A + 
Sbjct  180  QAGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGC  239

Query  241  GDEEKRCIREDIAQSVVQRCQQTQDAVVTELTQKREKTPPPLCFDLGMLQQVASRQWGMG  300
            +D+  RC+++  AQ   +R + +  A V  +T  R + +PPL FDLG LQ+V SRQ +++
Sbjct  240  SDDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALD  299

Query  301  AGQVLTIAQSLYETHKATTYPRTDCGYLPVSMRENIPAVFTALTRTDPAMSAIISQLDAS  360
              + L IAQ+LYETHKATTYPR+D GYLP SM  ++PAV++A+  TDP++ +++ QLD +
Sbjct  300  VQETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRT  359

Query  361  AFSRVWNDSQITAHPAIIPTRHTFDMTKLTADELKVYQLIRHYYLAQFLPAQETDVTDVT  420
              SR WNDS+++AH +IIPT +  +++ ++   L VY+LIR  YLAQFLP  E D T   
Sbjct  360  QRSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQ  419

Query  421  FTIGGQVFQAKGRVSVVTGWKALFADEKQAQEQEDNTA----LPALKKEEISPVLRAEIQ  476
            +  GGQ +QA G+  ++ GW  ++A+    + + +  +    LPAL+      V + +++
Sbjct  420  LLCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLSCQVNHVDLK  479

Query  477  PRQTRPPAPFTEGTLIAAMKNAAAFIHDPQLKKVLRESAGLGTEATRAGIIEalfkrrll  536
            + +T+PP P+T+G LI AMK  A ++ DP+LK+ L+E++G+GTEATRA+II +L+ R  L
Sbjct  480  ALKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERGYL  539

Query  537  arkkknlhaTQLAQELIAGLPDVLTHPGMTALWEQSLDDIARGRTTLDGFMQKQAQWLAH  596
             +K + ++A++ A  LI ++P  +T+PG TA+WEQ+LD I  G  TL+ F+ KQ+ W+++
Sbjct  540  LKKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWITQ  599

Query  597  LVEKGKTQPIRFTLPKTPACPRCGGPMQKRAGKTTPFWGCTRYPACKGMLNANA  650
            LV++ ++  + + LP  PACP CG++ ++R+GKT PFW+C RYP CKG L  + 
Sbjct  600  LVQQYRAATLAIKLPEGPACPLCGSATRQRTGKTGPFWSCCRYPDCKGTLPVQN  653

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  517 bits (1950),  Expect = 8e-148, Method: Compositional matrix adjust.
 Identities = 308/654 (48%), Positives = 469/654 (72%), Gaps = 5/654 (0%)

Query  1    MPLYLCEKPSQARDIARVLGVKQRGQGYLFGGSITVTWAIGHLLEMAAPEHYGEQFGPPW  60
            M L+LCEKPSQ++DIARVLG  QRG G   G++  VTW IGHL+E A+PE YGEQ+   W
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQY-KRW  59

Query  61   RMEPLPVLPAQWQWTVKKETADQFAVIRQLLKQADEVIIATDADREGEVIARELLEYCRF  120
             +E LP++P +W+   K  TA Q+ +++QL+ QA E++IATDADREGE+IARE+++ C +
Sbjct  60   SLEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGY  119

Query  121  TGPVRRLWLSALDETSIRQALAAILPGEQTESLWQAGLGRARADWLTGINLTRLYTLKAQ  180
             GP++RLWLSAL+++SIR+AL+A+ P+ ++ +L  A+L+R+RADWL G+NL+RL+TL ++
Sbjct  120  RGPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGR  179

Query  181  EQGFGEVLSIGRVQTPTLALVVNRDNDIARFEQKPYWQVMATLQKDDISFRAKWLPAPDD  240
            + G++ VLS+GRVQTPTLALVV RD +IARF   P+W +   L  ++ SF A W++A + 
Sbjct  180  QAGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGC  239

Query  241  GDEEKRCIREDIaqrvvqrcqqaqdavvTELTQKREKTPPPLCFDLGTLQQVASRQWGMG  300
            +D+  RC+++  AQ+  +R + A  A V  +T  R + +PPL FDLGTLQ+V SRQ +++
Sbjct  240  SDDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALD  299

Query  301  AGQVLTIAQSLYETHKATTYPRTDCGYLPVSMRENIPAVFTALTRTDPAMSAIISQLDAS  360
              + L IAQ+LYETHKATTYPR+D GYLP SM  ++PAV++A+  TDP++ +++ QLD +
Sbjct  300  VQETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRT  359

Query  361  AFSRVWNDSQITAHPAIIPTRHTFDMTKLTADELKVYQLIRHYYLAQFLPAQETDVTDVT  420
              SR WNDS+++AH +IIPT +  +++ ++   L VY+LIR  YLAQFLP  E D T   
Sbjct  360  QRSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQ  419

Query  421  FTIGGQVFQAKGRVSVVTGWKALFADEKQAQEQEDNTA----LPALKKEEISPVLRAEIQ  476
            +  GGQ +QA G+  ++ GW  ++A+    + + +  +    LPAL+      V + +++
Sbjct  420  LLCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLSCQVNHVDLK  479

Query  477  PRQTRPPAPFTEGTLIAAMKNAAAFIHDPQLKKVLRESAGLGTEATRAGIIEalfkrrll  536
            + +T+PP P+T+G LI AMK  A ++ DP+LK+ L+E++G+GTEATRA+II +L+ R  L
Sbjct  480  ALKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERGYL  539

Query  537  arkkknlhaTQLAQELIAGLPDVLTHPGMTALWEQSLDDIARGRTTLDGFMQKQAQWLAH  596
             +K + ++A++ A  LI ++P  +T+PG TA+WEQ+LD I  G  TL+ F+ KQ+ W+++
Sbjct  540  LKKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWITQ  599

Query  597  LVEKGKTQPIRFTLPKTPACPRCGGPMQKRAGKTTPFWGCTRYPACKGMLNANA  650
            LV++ ++  + + LP  PACP CG++ ++R+GKT PFW+C RYP CKG L  + 
Sbjct  600  LVQQYRAATLAIKLPEGPACPLCGSATRQRTGKTGPFWSCCRYPDCKGTLPVQN  653

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  507 bits (1913),  Expect = 6e-145, Method: Compositional matrix adjust.
 Identities = 313/653 (48%), Positives = 465/653 (72%), Gaps = 21/653 (3%)

Query  4    IYLCEKPSQGQDIARVLGATRKGNGCRSTQSEEVVVTWCFGHLLEMPPPEAYDPALKSWA  63
            ++LCEKPSQG+DIARVLGA ++G+GC   ++   VVTWC+GHL+E +PPEAY+   K W+
Sbjct  3    LFLCEKPSQGKDIARVLGAGQRGSGC--YNGAGTVVTWCIGHLIEAAPPEAYGEQYKRWS  60

Query  64   LDTLPIIPEQWRLVVKPSAQRQFTVIKKWLGSASRLVIATDADREGEVIAREVMALCGYR  123
            L+ LPIIPE+WR+  K+++  Q+ ++K+ +G AS LVIATDADREGE+IARE++ LCGYR
Sbjct  61   LEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGYR  120

Query  124  GPVQRLWLSALNDASIRKALSQLRDGKQTYPLYLAGMARARADWLVGMNLTRAYTVLGRN  183
            GP+QRLWLSALNDASIRKAL+ L+ + ++ PLY A++AR+RADWLVGMNL+R +T+LGR+
Sbjct  121  GPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGRQ  180

Query  184  AGYQGVLSVGRVQTPTLRLVVDRDRAIEAFKPSPYWTITSTLSAQGAAAPAFRAHWQPAA  243
            AGY+GVLSVGRVQTPTL LVV RDR I  F + P+W+I   LS+ G    +F A W +A 
Sbjct  181  AGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGG---HSFLATWIAAD  237

Query  244  EHCDSQGRCINETVARTVAQQCSVTGAQAHVTDSKKERKAAPPPLPFDLNSLQQEAGKRF  303
               D  GRC++++ A+  A++  V+G+ A+V     ER   +PPLPFDL +LQ+  ++++
Sbjct  238  GCSDDAGRCLQQATAQQAADRLRVAGS-AQVVAVTTERVREAPPLPFDLGTLQDVCSRQL  296

Query  304  DLSGNQVLEAAQALYETHKITSYPRTECRHLPTSMHGEAPDVLRAVLAMEPELTSIQSML  363
             L  ++ L+ AQALYETHK T+YPR++   LP SM +E P VL A+L+ +P L ++   L
Sbjct  297  ALDVQETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQL  356

Query  364  DMSRRTKTWNDTEVEKASHHGIIPTAESADLTRLSTTERQVYGLIRRHYLIQFLPDHQYD  423
            D ++R+++WND+ V  ++HHGIIPT E+A+L+ +S     VY LIR HYL QFLP+ ++D
Sbjct  357  DRTQRSRAWNDSKV--SAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFD  414

Query  424  ATTLTLSVQGHPFLAKGKATVEPGWTRLFPSSKSTPqdgddqqdgsgdqgTVPALPEGTS  483
             TT  L   G+ + A GK  + PGW +++++    P+ ++ + ++      +PAL EG S
Sbjct  415  RTTAQLLCGGQTLQAVGKQVIIPGWHQVLAG----PEADNADGEAVPRSQVLPALREGLS  470

Query  484  CAIQSVDCDRKMTTPPARYTDGTLIAAMKNIAKMVTDPKLRAVLRDTAGLGTGATRANII  543
            C ++ VD     T PP  YT+G LI AMK +AK+VTDP+L+  L++T+G+GT ATRA+II
Sbjct  471  CQVNHVDLKALKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASII  530

Query  544  ATLKKRGFIEKKRGHLVSTEQGRQLIDALPSAITNPDTTAAWEQALEDIATGTGTLDEFM  603
              L  RG++ KK   + +++ + +LIDA+P+AIT+P+TTA WEQAL+ I +G  TL+ F+
Sbjct  531  KGLLERGYLLKKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFV  590

Query  604  RRQLDWLNTVVTHAKGQTLSALAATVKDNALPCQ-CGGSATE-TAKS---WRC  651
             +Q  W+  +V + ++   ++LA  + + + +C  CG+++ + T+K+   W C
Sbjct  591  AKQSTWITQLVQQYRA---ATLAIKLPEGP-ACPLCGSATRQRTGKTGPFWSC  639

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  484 bits (1823),  Expect = 8e-138, Method: Compositional matrix adjust.
 Identities = 297/605 (50%), Positives = 441/605 (73%), Gaps = 4/605 (0%)

Query  1    MRVYLCEKPSQARDIAAVLGIQSKDKSSITTADGVVTWAFGHLLEQAPPDAYDDSLKRWA  60
            MR++LCEKPSQ++DIA VLG   ++ +    A+ VVTW +GHL+E APP+AY++  KRW+
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQYKRWS  60

Query  61   LASLPIAPTQWKVEVKSSAKDQFKAIATLLKRATEVVIATDADREGEMIARELMAFVGFK  120
            L  LPI P +W+VE K+++  Q+K +  L+ +A+E+VIATDADREGEMIARE++ + G++
Sbjct  61   LEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGYR  120

Query  121  GKVQRLWlsaldaasvkkalaalkpsaETAGLYQSALGRSRADWLVGMNLTRAFTLAGCS  180
            G +QRLWLSAL+ AS++KAL+ALKPS+E+  LY +AL+RSRADWLVGMNL+R FTL G  
Sbjct  121  GPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGRQ  180

Query  181  QGGEGVRSVGRVQTPTLSLVVARDRQIEHFKPVPYFEL-FGFFEAGQSFSTKWKVPEGAG  239
             G +GV SVGRVQTPTL+LVV+RDR+I +F +VP+  +  G+  +G+SF + W  ++G +
Sbjct  181  AGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGCS  240

Query  240  DDAGRCVDQSIVDAVASKI-TGKTGTVSQYETKRISENPPLPFSLSTLQKTCSAKFGLGA  298
            DDAGRC++Q+  +  A ++  + ++ V    T R+ E PPLPF L+TLQ  CS +++L+ 
Sbjct  241  DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALDV  300

Query  299  QEVLDIAQALYETHKATTYPRSDCNFLPEEQFQEASSIVTALAKSDTEVQGIVDLLDFSR  358
            QE LDIAQALYETHKATTYPRSD  +LPE  + E +++++A+  +D  ++ +++ LD ++
Sbjct  301  QETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRTQ  360

Query  359  KSPAWNTKKITAHHAIIPTQTPPNMDAMSDNERRVYELIRRQYLAQFLPNYEYDRTQIGI  418
            +S AWN  K++AHH+IIPT  P+N+ A+SD+   VY LIR +YLAQFLP+YE+DRT   +
Sbjct  361  RSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQL  420

Query  419  SIEGELFQTTGKIDQVTGWRVLFGKADASDDEPDD--EVQTLPALTQGQTLPLSHTEIAA  476
               G+ +Q+ GK   + GW+ +++ ++A + + +     Q LPAL +G +  ++H ++ A
Sbjct  421  LCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLSCQVNHVDLKA  480

Query  477  KQTKPPSRYTEGTLIDAMQTIGKNITDPRLKAILKENSGIGTEATRAGIIANLIERGFIT  536
             +T+PP  YT+G LI AM+ ++K +TDPRLK  LKE +GIGTEATRA+II  L+ERG++ 
Sbjct  481  LKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERGYLL  540

Query  537  KKGKQVISSDVGRQLIDALPDSVKSPALTALWEQSLEEIAEGKRELAGFEADVVKFITAI  596
            KKG+ V +SD + +LIDA+P ++  P+ TA+WEQ+L+ I  G   L  F A     IT +
Sbjct  541  KKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWITQL  600

Query  597  IDQIK  601
            ++Q +
Sbjct  601  VQQYR  605

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  480 bits (1808),  Expect = 2e-136, Method: Compositional matrix adjust.
 Identities = 321/684 (47%), Positives = 466/684 (69%), Gaps = 38/684 (5%)

Query  1    MILYLCEKPSQGRDIGRVLGATSRHEGYVAGAGVCVTWCIGHLMEMVAPDGYRPEWKSWR  60
            M L+LCEKPSQG+DI+RVLGA  R  G   GAG  VTWCIGHL+E  +P++Y  + K W 
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQYKRWS  60

Query  61   LDTLPIIPQQWQLELTARGRKQFKVIQGLLKGVTEVVLATDADREGETIGREVLERCQYR  120
            L+ LPIIP++W++E  A    Q+K+++ L+   +E+V+ATDADREGE I+RE+++ C YR
Sbjct  61   LEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGYR  120

Query  121  GKISRLWLSALDDASIRKALGNLLPGEQTEPLYQAGLGRSRADWMVGMNLTRAYTLLGRQ  180
            G I RLWLSAL+DASIRKALG L P+ ++ PLY A+L+RSRADW+VGMNL+R +TLLGRQ
Sbjct  121  GPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGRQ  180

Query  181  GGYAGVLSVGRVQTPTLKLVVDRDRLIENFKPVDYFEIFALHRVHSGTFIAKWVPPPKPC  240
            +GY GVLSVGRVQTPTL LVV RDR I  F +V +  I       + +F+A W+++    
Sbjct  181  AGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGCS  240

Query  241  DAEGHCLDRTLAETVIHKVQ-GHSGTITKAETKRVKeppplplelSTLQQEASRRWGMGA  299
            D  G+CL+++ A+   ++++ + S+ +    T RV+E+PPLP++L+TLQ+  SR+ +++ 
Sbjct  241  DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALDV  300

Query  300  KQTLEIAQSLYEKHKAVTYPRTDCRYLPSNQFKEAPAVLQGLTTNDASLTPLVEGADAQL  359
            ++TL+IAQ+LYE HKA TYPR+D  YLP + + E PAVL ++ T D+SL PL+E  D   
Sbjct  301  QETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRTQ  360

Query  360  RSKAWNDKkitahhaiiptaakiNIDALSREEALLYDLIRRHYLAQFYPPFEYDRTVIDT  419
            RS+AWND K++AHH+IIPT    N+ A+S     +Y LIR HYLAQF P +E+DRT  + 
Sbjct  361  RSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQL  420

Query  420  QVAMETFHATGRVELIPGWKRVLAANQEKKEGDED---EQTLPVVRSGEAATIEGAELKQ  476
              + +T++A G+  +IPGW +VLA+ +  + ++E     Q LP +R G +  ++  +LK 
Sbjct  421  LCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLSCQVNHVDLKA  480

Query  477  KQTKPPNRYTEGTLIQAMKSVGKLVEDARLRKILRETSGIGTEATRAAILETLIKRNLLA  536
             +T+PP+ YT+G LI+AMK+V+KLV D+RL++ L+ET+GIGTEATRA+I+  L+ R  L 
Sbjct  481  LKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERGYLL  540

Query  537  KQGKKSLVSMPAGRLLVDALPHSVTDPATTAVWEQTLDDIAHGGGSLETFLAKSELWLNK  596
            K+G+    S +AGR L+DA+P ++TDP+TTAVWEQ+LD I  G+ +LETF+AK   W+ +
Sbjct  541  KKGRTVRASDAAGR-LIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWITQ  599

Query  597  LIHNVHQRQQLGLNPFRGLPPSTSHTDPAQPTPRRQRRSKAEVTPTPNAAPLCPQCGGPM  656
            L+++           +R+                      A ++     +P CP CG++ 
Sbjct  600  LVQQ-----------YRA----------------------ATLAIKLPEGPACPLCGSAT  626

Query  657  LQRKSPQGAFWSCAEQATCTGTRP  680
             QR +  G+FWSC   + C GT P
Sbjct  627  RQRTGKTGPFWSCCRYPDCKGTLP  650


 Score = 34.5 bits (111),  Expect = 0.020, Method: Compositional matrix adjust.
 Identities = 19/37 (52%), Positives = 23/37 (63%), Gaps = 6/37 (16%)

Query  698  GPLCPKCQQAPLVQRTAYRGKNSGQPFWGCQRYPQCR  734
            GP CP C  A   QRT   GK +  PFW+C RYP+C+
Sbjct  616  GPACPLCGSAT-RQRT---GKTG--PFWSCCRYPDCK  646

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  476 bits (1794),  Expect = 1e-135, Method: Compositional matrix adjust.
 Identities = 293/557 (53%), Positives = 418/557 (76%), Gaps = 6/557 (1%)

Query  2    AAPEDYDPALKHWRAEHLPFIPPAWRLVIRPEVRKQFRIIEKLLKQADAVVIATDADREG  61
            A+PE Y+   K+W  E+LP+IP  WR+  ++    Q++I+ +L+ QA  +VIATDADREG
Sbjct  47   APPEAYGEQYKRWSLEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREG  106

Query  62   ETIAREILEQCRWRGPVQRLWLSALDDASIHKALAAMRSGDSTYPLYQAGLARARADWLV  121
            E IAREI++ C  RGP+QRLWLSAL+DASI+KAL+A++++  + PLY A+LAR+RADWLV
Sbjct  107  EMIAREIIDLCGYRGPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLV  166

Query  122  GINMTRACTLMNRR--HKGVLSVGRVQTPTLRLVVERDREISRFTPRPWWRVDARLHAEG  179
            G+N++R  TL+ R+    GVLSVGRVQTPTL LVV RDREI+RF + P W ++  L + G
Sbjct  167  GMNLSRLFTLLGRQAGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGG  226

Query  180  TTFLAQWQPDGVYCDDEGRCIRESAAREATASLQQAGTTLVLDVTTRREKTPPPLAFTLS  239
             +FLA W + +   DD GRC+++++A++A+  L+ AG++ V+ VTT R + +PPL+F L+
Sbjct  227  HSFLATWIAADGCSDDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLG  286

Query  240  ALQQVCSKQWGMGAQEVLDIAQRLYETHKATTYPRTDCGWLPLSMHTEAPQVLAALVASD  299
            +LQ+VCS+Q +++ QE LDIAQ LYETHKATTYPR+D G LP SM +E P VLAA++++D
Sbjct  287  TLQDVCSRQLALDVQETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTD  346

Query  300  ISLQPLATQLNLQQHSRLWDDSKITAHHGIIPTRKTVDLTQMNDSERKVYGLVRSHFLAQ  359
             SL+PL  QL+  Q+SR W+DSK++AHHGIIPT    +L+ ++D    VY L+R+H+LAQ
Sbjct  347  PSLRPLLEQLDRTQRSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQ  406

Query  360  FLSDHEVDKTDLRLNCAGETLAARGSVVIVSGWQQLFLREMATHSPEE----TQSLPVLQ  415
            FL++ E D+T  +L C+G+TL A G  VI++GW+Q++    A ++  E    +Q LP L+
Sbjct  407  FLPHYEFDRTTAQLLCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALR  466

Query  416  QGQTCQVEQVDVRARQTQPPEHYTEGTLIAAMKNAARFVSDERLKQRLKENAGIGTEATR  475
            +G +CQV++VD++A +TQPP  YT+G LI AMK  A++V+D RLKQ+LKE +GIGTEATR
Sbjct  467  EGLSCQVNHVDLKALKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATR  526

Query  476  AGIIQTLLKRGYLIKQRRFLLATDTASALIDALPEKLKDPGTTALWEQMLDDIATGKMGL  535
            A+II+ LL RGYL+K+ R + A+D+A+ LIDA+P  + DPGTTA+WEQ LD I +G M L
Sbjct  527  ASIIKGLLERGYLLKKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTL  586

Query  536  EAFLVQQQETVTALTAQ  552
            E+F+ +Q   +T L  Q
Sbjct  587  ETFVAKQSTWITQLVQQ  603

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  467 bits (1761),  Expect = 7e-133, Method: Compositional matrix adjust.
 Identities = 288/675 (43%), Positives = 449/675 (67%), Gaps = 23/675 (3%)

Query  1    MDLYICEKPSQAKDLAGVMKASQRGDGFIHDGGNRVITWAFGHLLELYMPDDYDERYKSW  60
            M L++CEKPSQ+KD+A V+ A+QRG G   +G+  V+TW +GHL+E   P+ Y+E+YK W
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSG-CYNGAGTVVTWCIGHLIEAAPPEAYGEQYKRW  59

Query  61   SLETLPIAPDAWRYNVRKSALKQYKIVEGLVKKASTIYISTDFDREGEAIARSLLDQFRY  120
            SLE LPI P+ WR + + ++  Q KIV  LV +AS + I+TD DREGE IAR ++D   Y
Sbjct  60   SLEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGY  119

Query  121  SGPIRRVCLTALDESSIKKALNNVKDGKETVSLYYAALARQRADWLVGMNVSRLYTVLAR  180
             GPI+R+ L+AL+++SI+KAL  +K + E+++LY AALAR RADWLVGMN+SRL+T+L+R
Sbjct  120  RGPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGR  179

Query  181  DVGFNHTLHVGRVITPTVALVCQRDREIAGFTPSPYWTLGVNVSVQNGQFAAQWIPPEEC  240
            + G++  L VGRV TPT+ALV  RDREIA F + P+W++ V +S     F A WI+++ C
Sbjct  180  QAGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGC  239

Query  241  SDEQGRCINKAYAEQVSS--QVNGANAVISKAETKPGKESAPLPFDLTSLQQYASKRWGY  298
            SD+ GRC+++A A+Q +   +V G+  V++   T   +E++PLPFDL +LQ+  S++ + 
Sbjct  240  SDDAGRCLQQATAQQAADRLRVAGSAQVVA-VTTERVREAPPLPFDLGTLQDVCSRQLAL  298

Query  299  TAQQVLDAAQALYETHKATTYPRTDSRYLPESQKEDIPDILQALILSDQNVSGLVAGADP  358
              Q+ LD AQALYETHKATTYPR+DS YLPES   ++P +L A++ +D ++  L+   D 
Sbjct  299  DVQETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDR  358

Query  359  HRKARVFNDSKVTAHHAIIPTPARTDISAMSEIELNLYDAIRRFYIAQFYSEFEFTKTSI  418
             +++R  NDSKV+AHH+IIPT   ++++A+S+  L +Y  IR  Y+AQF +++EF +T+ 
Sbjct  359  TQRSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTA  418

Query  419  EVQCGRHLFAASGKTPTKQGWKVLFASDSESSPKDEGEDTDAPVEQEKLPRVSQGEPALL  478
            ++ CG + + A GK     GW  ++A     +P  +  D +A    + LP + +G +  +
Sbjct  419  QLLCGGQTLQAVGKQVIIPGWHQVLA-----GPEADNADGEAVPRSQVLPALREGLSCQV  473

Query  479  NGTELMNKMTRPAPHFTEATLLAAMENIARFVTEEKFKQILKDTAGLGTPATRASIIQGT  538
            N  +L    T+P+  +T++ L+ AM  +A++VT+ ++KQ LK+T+G+GT ATRASII+G 
Sbjct  474  NHVDLKALKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGL  533

Query  539  VDKGYFKRQKKVLLATDKAHALIAVLPPAIKSPGMTAAWEQELEKVATGSGNMSVFMKQI  598
            +++GY+ ++ + + A+D A  LI  +P+AI  PG TA WEQ L+ + +G   +  F+ + 
Sbjct  534  LERGYLLKKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQ  593

Query  599  STWICQMVDQLKVAAPVLTKEGSAMAKAFEGAKPPSHECFNCGGEMHRIKGKNGFFWG-C  657
            STWI Q+V+Q + A             ++    P +  C  CG+  ++  GK G FW+ C
Sbjct  594  STWITQLVQQYRAA-------------TLAIKLPEGPACPLCGSATRQRTGKTGPFWSCC  640

Query  658  QNEACKKTFPDNRGK  672
            +   CK T+P + G+
Sbjct  641  RYPDCKGTLPVQNGR  655


 Score = 47.1 bits (159),  Expect = 3e-06, Method: Compositional matrix adjust.
 Identities = 21/44 (48%), Positives = 29/44 (66%), Gaps = 6/44 (13%)

Query  683  PDCPDCGSPMRLRKGKAPGKKRASKFWGCTAYPDCKGTMPFKKS  726
            P CP CGS+ R R GK+      + FW+C  YPDCKGT+P +++
Sbjct  617  PACPLCGSATRQRTGKT------GPFWSCCRYPDCKGTLPVQNG  654

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  466 bits (1758),  Expect = 1e-132, Method: Compositional matrix adjust.
 Identities = 288/675 (43%), Positives = 449/675 (67%), Gaps = 23/675 (3%)

Query  1    MDLYICEKPSQAKDLAGVMKASQRGDGFIHDGGNRVITWAFGHLLELYMPDDYDERYKSW  60
            M L++CEKPSQ+KD+A V+ A+QRG G   +G+  V+TW +GHL+E   P+ Y+E+YK W
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSG-CYNGAGTVVTWCIGHLIEAAPPEAYGEQYKRW  59

Query  61   SLETLPIAPDAWRYNVRKSALKQYKIVEGLVKKASTIYISTDFDREGEAIARSLLDQFRY  120
            SLE LPI P+ WR + + ++  Q KIV  LV +AS + I+TD DREGE IAR ++D   Y
Sbjct  60   SLEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGY  119

Query  121  SGPIRRVCLTALDESSIKKALNNVKDGKETVSLYYAALARQRADWLVGMNVSRLYTVLAR  180
             GPI+R+ L+AL+++SI+KAL  +K + E+++LY AALAR RADWLVGMN+SRL+T+L+R
Sbjct  120  RGPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGR  179

Query  181  DVGFNHTLHVGRVITPTVALVCQRDREIAGFTPSPYWTLGVNVSVQNGQFAAQWIPPEEC  240
            + G++  L VGRV TPT+ALV  RDREIA F + P+W++ V +S     F A WI+++ C
Sbjct  180  QAGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGC  239

Query  241  SDEQGRCINKAYAEQVSS--QVNGANAVISKAETKPGKESAPLPFDLTSLQQYASKRWGY  298
            SD+ GRC+++A A+Q +   +V G+  V++   T   +E++PLPFDL +LQ+  S++ + 
Sbjct  240  SDDAGRCLQQATAQQAADRLRVAGSAQVVA-VTTERVREAPPLPFDLGTLQDVCSRQLAL  298

Query  299  TAQQVLDAAQALYETHKATTYPRTDSRYLPESQKENIPDILQALILSDQNVSGLVAGADP  358
              Q+ LD AQALYETHKATTYPR+DS YLPES   ++P +L A++ +D ++  L+   D 
Sbjct  299  DVQETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDR  358

Query  359  HRKARVFNDSKVTAHHAIIPTPARTDISAMSEIELNLYDAIRRFYIAQFYSEFEFTKTSI  418
             +++R  NDSKV+AHH+IIPT   ++++A+S+  L +Y  IR  Y+AQF +++EF +T+ 
Sbjct  359  TQRSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTA  418

Query  419  EVQCGRHLFAASGKTPTKQGWKVLFASDSESSPKDEGEDTDAPVEQEKLPRVSQGEPALL  478
            ++ CG + + A GK     GW  ++A     +P  +  D +A    + LP + +G +  +
Sbjct  419  QLLCGGQTLQAVGKQVIIPGWHQVLA-----GPEADNADGEAVPRSQVLPALREGLSCQV  473

Query  479  NGTELMNKMTRPAPHFTEATLLAAMENIARFVTEEKFKQILKDTAGLGTPATRASIIQGT  538
            N  +L    T+P+  +T++ L+ AM  +A++VT+ ++KQ LK+T+G+GT ATRASII+G 
Sbjct  474  NHVDLKALKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGL  533

Query  539  VDKGYFKRQKKVLLATDKAHALIAVLPPAIKSPGMTAAWEQELEKVATGSGNMSVFMKQI  598
            +++GY+ ++ + + A+D A  LI  +P+AI  PG TA WEQ L+ + +G   +  F+ + 
Sbjct  534  LERGYLLKKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQ  593

Query  599  STWICQMVDQLKVAAPVLTKEGSAMAKAFEGAKPPSHECFNCGGEMHRIKGKNGFFWG-C  657
            STWI Q+V+Q + A             ++    P +  C  CG+  ++  GK G FW+ C
Sbjct  594  STWITQLVQQYRAA-------------TLAIKLPEGPACPLCGSATRQRTGKTGPFWSCC  640

Query  658  QNEACKKTFPDNRGK  672
            +   CK T+P + G+
Sbjct  641  RYPDCKGTLPVQNGR  655


 Score = 47.1 bits (159),  Expect = 3e-06, Method: Compositional matrix adjust.
 Identities = 21/44 (48%), Positives = 29/44 (66%), Gaps = 6/44 (13%)

Query  683  PDCPDCGSPMRLRKGKAPGKKRASKFWGCTAYPDCKGTMPFKKS  726
            P CP CGS+ R R GK+      + FW+C  YPDCKGT+P +++
Sbjct  617  PACPLCGSATRQRTGKT------GPFWSCCRYPDCKGTLPVQNG  654

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  465 bits (1752),  Expect = 4e-132, Method: Compositional matrix adjust.
 Identities = 286/675 (43%), Positives = 449/675 (67%), Gaps = 23/675 (3%)

Query  1    MDLYICEKPSQAKDLAGVMKASQRGDGFLHDGGNRVITWAFGHLLELYMPDDYDERYKSW  60
            M L++CEKPSQ+KD+A V+ A+QRG G   +G+  V+TW +GHL+E   P+ Y+E+YK W
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGC-YNGAGTVVTWCIGHLIEAAPPEAYGEQYKRW  59

Query  61   SLETLPIAPESWRYNVRKSAFKQYKIVEGLVKKASTIYISTDYDREGEAIARSLLDRFRY  120
            SLE LPI PE WR + + ++  Q KIV  LV +AS + I+TD DREGE IAR ++D   Y
Sbjct  60   SLEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGY  119

Query  121  SGPIRRVCLTALDESSIKKALNNVKDGKDTVSLYYAALARQRADWLVGMNVSRLYTVLAR  180
             GPI+R+ L+AL+++SI+KAL  +K + ++++LY AALAR RADWLVGMN+SRL+T+L+R
Sbjct  120  RGPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGR  179

Query  181  DVGFNHTLHVGRVITPTVALVCQRDREIAGFTPSPYWTLGVNVSVQNGQFAAQWIPPEEC  240
            + G++  L VGRV TPT+ALV  RDREIA F + P+W++ V +S     F A WI+++ C
Sbjct  180  QAGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGC  239

Query  241  SDEQGRCVNKAYAEQVAS--QVNGANAVISKAETKPGKESAPLPFDLTSLQQYASKRWGY  298
            SD+ GRC+++A A+Q A   +V G+  V++   T   +E++PLPFDL +LQ+  S++ + 
Sbjct  240  SDDAGRCLQQATAQQAADRLRVAGSAQVVA-VTTERVREAPPLPFDLGTLQDVCSRQLAL  298

Query  299  TAQQVLDAAQALYETHKATTYPRTDSRYLPESQKEDIPDILQALILSDQNVSGLVAGADP  358
              Q+ LD AQALYETHKATTYPR+DS YLPES   ++P +L A++ +D ++  L+   D 
Sbjct  299  DVQETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDR  358

Query  359  HRKARVFNDAKVTAHHAIIPTPARTDISAMSEIEFNLYDAIRRFYIAQFYSEFEFTKTSI  418
             +++R  ND+KV+AHH+IIPT   ++++A+S+  + +Y  IR  Y+AQF +++EF +T+ 
Sbjct  359  TQRSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTA  418

Query  419  EVQCGRHLFASAGKTPTKQGWKVLFASDSESSPKDEGEDTDAPVEQEKLPRVSQGEPALL  478
            ++ CG + + + GK     GW  ++A     +P  +  D +A    + LP + +G +  +
Sbjct  419  QLLCGGQTLQAVGKQVIIPGWHQVLA-----GPEADNADGEAVPRSQVLPALREGLSCQV  473

Query  479  NGAELANKMTRPAPHFTEATLLAAMENIARFVTEEKFKQILKDTAGLGTPATRASIIQGA  538
            N  +L    T+P+  +T++ L+ AM  +A++VT+ ++KQ LK+T+G+GT ATRASII+G 
Sbjct  474  NHVDLKALKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGL  533

Query  539  VDKGYFKRQKKVLLATDKAHALIAVLPPAIKSPGMTAAWEQELEKVASGSGNMSVFMKQI  598
            +++GY+ ++ + + A+D A  LI  +P+AI  PG TA WEQ L+ + +G   +  F+ + 
Sbjct  534  LERGYLLKKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQ  593

Query  599  STWICQMVEQLKVAAPVLTKEGGAMAKAFEGAKPPSHECFNCGGEMHRIKGKNGFFWG-C  657
            STWI Q+V+Q + A             ++    P +  C  CG+  ++  GK G FW+ C
Sbjct  594  STWITQLVQQYRAA-------------TLAIKLPEGPACPLCGSATRQRTGKTGPFWSCC  640

Query  658  QNEACKKTFPDNRGK  672
            +   CK T+P + G+
Sbjct  641  RYPDCKGTLPVQNGR  655


 Score = 47.1 bits (159),  Expect = 3e-06, Method: Compositional matrix adjust.
 Identities = 21/44 (48%), Positives = 29/44 (66%), Gaps = 6/44 (13%)

Query  683  PDCPDCGSPMRLRKGKAPGKKRASKFWGCTAYPDCKGTMPFKKS  726
            P CP CGS+ R R GK+      + FW+C  YPDCKGT+P +++
Sbjct  617  PACPLCGSATRQRTGKT------GPFWSCCRYPDCKGTLPVQNG  654

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  465 bits (1752),  Expect = 4e-132, Method: Compositional matrix adjust.
 Identities = 286/675 (43%), Positives = 449/675 (67%), Gaps = 23/675 (3%)

Query  1    MDLYICEKPSQAKDLAGVMKASQRGDGFLHDGGNRVITWAFGHLLELYMPDDYDERYKSW  60
            M L++CEKPSQ+KD+A V+ A+QRG G   +G+  V+TW +GHL+E   P+ Y+E+YK W
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGC-YNGAGTVVTWCIGHLIEAAPPEAYGEQYKRW  59

Query  61   SLETLPIAPESWRYNVRKSAFKQYKIVEGLVKKASTIYISTDYDREGEAIARSLLDRFRY  120
            SLE LPI PE WR + + ++  Q KIV  LV +AS + I+TD DREGE IAR ++D   Y
Sbjct  60   SLEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGY  119

Query  121  SGPIRRVCLTALDESSIKKALNNVKDGKDTVSLYYAALARQRADWLVGMNVSRLYTVLAR  180
             GPI+R+ L+AL+++SI+KAL  +K + ++++LY AALAR RADWLVGMN+SRL+T+L+R
Sbjct  120  RGPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGR  179

Query  181  DVGFNHTLHVGRVITPTVALVCQRDREIAGFTPSPYWTLGVNVSVQNGQFAAQWIPPEEC  240
            + G++  L VGRV TPT+ALV  RDREIA F + P+W++ V +S     F A WI+++ C
Sbjct  180  QAGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGC  239

Query  241  SDEQGRCVNKAYAEQVAS--QVNGANAVISKAETKPGKESAPLPFDLTSLQQYASKRWGY  298
            SD+ GRC+++A A+Q A   +V G+  V++   T   +E++PLPFDL +LQ+  S++ + 
Sbjct  240  SDDAGRCLQQATAQQAADRLRVAGSAQVVA-VTTERVREAPPLPFDLGTLQDVCSRQLAL  298

Query  299  TAQQVLDAAQALYETHKATTYPRTDSRYLPESQKEDIPDILQALILSDQNVSGLVAGADP  358
              Q+ LD AQALYETHKATTYPR+DS YLPES   ++P +L A++ +D ++  L+   D 
Sbjct  299  DVQETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDR  358

Query  359  HRKARVFNDAKVTAHHAIIPTPARTDISAMSEIEFNLYDAIRRFYIAQFYSEFEFTKTSI  418
             +++R  ND+KV+AHH+IIPT   ++++A+S+  + +Y  IR  Y+AQF +++EF +T+ 
Sbjct  359  TQRSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTA  418

Query  419  EVQCGRHLFASAGKTPTKQGWKVLFASDSESSPKDEGEDTDAPVEQEKLPRVSQGEPALL  478
            ++ CG + + + GK     GW  ++A     +P  +  D +A    + LP + +G +  +
Sbjct  419  QLLCGGQTLQAVGKQVIIPGWHQVLA-----GPEADNADGEAVPRSQVLPALREGLSCQV  473

Query  479  NGAELANKMTRPAPHFTEATLLAAMENIARFVTEEKFKQILKDTAGLGTPATRASIIQGA  538
            N  +L    T+P+  +T++ L+ AM  +A++VT+ ++KQ LK+T+G+GT ATRASII+G 
Sbjct  474  NHVDLKALKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGL  533

Query  539  VDKGYFKRQKKVLLATDKAHALIAVLPPAIKSPGMTAAWEQELEKVASGSGNMSVFMKQI  598
            +++GY+ ++ + + A+D A  LI  +P+AI  PG TA WEQ L+ + +G   +  F+ + 
Sbjct  534  LERGYLLKKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQ  593

Query  599  STWICQMVEQLKVAAPVLTKEGGAMAKAFEGAKPPSHECFNCGGEMHRIKGKNGFFWG-C  657
            STWI Q+V+Q + A             ++    P +  C  CG+  ++  GK G FW+ C
Sbjct  594  STWITQLVQQYRAA-------------TLAIKLPEGPACPLCGSATRQRTGKTGPFWSCC  640

Query  658  QNEACKKTFPDNRGK  672
            +   CK T+P + G+
Sbjct  641  RYPDCKGTLPVQNGR  655


 Score = 47.1 bits (159),  Expect = 3e-06, Method: Compositional matrix adjust.
 Identities = 21/44 (48%), Positives = 29/44 (66%), Gaps = 6/44 (13%)

Query  683  PDCPDCGSPMRLRKGKAPGKKRASKFWGCTAYPDCKGTMPFKKS  726
            P CP CGS+ R R GK+      + FW+C  YPDCKGT+P +++
Sbjct  617  PACPLCGSATRQRTGKT------GPFWSCCRYPDCKGTLPVQNG  654

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  465 bits (1752),  Expect = 4e-132, Method: Compositional matrix adjust.
 Identities = 286/675 (43%), Positives = 449/675 (67%), Gaps = 23/675 (3%)

Query  1    MDLYICEKPSQAKDLAGVMKASQRGDGFLHDGGNRVITWAFGHLLELYMPDDYDERYKSW  60
            M L++CEKPSQ+KD+A V+ A+QRG G   +G+  V+TW +GHL+E   P+ Y+E+YK W
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGC-YNGAGTVVTWCIGHLIEAAPPEAYGEQYKRW  59

Query  61   SLETLPIAPESWRYNVRKSAFKQYKIVEGLVKKASTIYISTDYDREGEAIARSLLDRFRY  120
            SLE LPI PE WR + + ++  Q KIV  LV +AS + I+TD DREGE IAR ++D   Y
Sbjct  60   SLEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGY  119

Query  121  SGPIRRVCLTALDESSIKKALNNVKDGKDTVSLYYAALARQRADWLVGMNVSRLYTVLAR  180
             GPI+R+ L+AL+++SI+KAL  +K + ++++LY AALAR RADWLVGMN+SRL+T+L+R
Sbjct  120  RGPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGR  179

Query  181  DVGFNHTLHVGRVITPTVALVCQRDREIAGFTPSPYWTLGVNVSVQNGQFAAQWIPPEEC  240
            + G++  L VGRV TPT+ALV  RDREIA F + P+W++ V +S     F A WI+++ C
Sbjct  180  QAGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGC  239

Query  241  SDEQGRCVNKAYAEQVAS--QVNGANAVISKAETKPGKESAPLPFDLTSLQQYASKRWGY  298
            SD+ GRC+++A A+Q A   +V G+  V++   T   +E++PLPFDL +LQ+  S++ + 
Sbjct  240  SDDAGRCLQQATAQQAADRLRVAGSAQVVA-VTTERVREAPPLPFDLGTLQDVCSRQLAL  298

Query  299  TAQQVLDAAQALYETHKATTYPRTDSRYLPESQKEDIPDILQALILSDQNVSGLVAGADP  358
              Q+ LD AQALYETHKATTYPR+DS YLPES   ++P +L A++ +D ++  L+   D 
Sbjct  299  DVQETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDR  358

Query  359  HRKARVFNDAKVTAHHAIIPTPARTDISAMSEIEFNLYDAIRRFYIAQFYSEFEFTKTSI  418
             +++R  ND+KV+AHH+IIPT   ++++A+S+  + +Y  IR  Y+AQF +++EF +T+ 
Sbjct  359  TQRSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTA  418

Query  419  EVQCGRHLFASAGKTPTKQGWKVLFASDSESSPKDEGEDTDAPVEQEKLPRVSQGEPALL  478
            ++ CG + + + GK     GW  ++A     +P  +  D +A    + LP + +G +  +
Sbjct  419  QLLCGGQTLQAVGKQVIIPGWHQVLA-----GPEADNADGEAVPRSQVLPALREGLSCQV  473

Query  479  NGAELANKMTRPAPHFTEATLLAAMENIARFVTEEKFKQILKDTAGLGTPATRASIIQGA  538
            N  +L    T+P+  +T++ L+ AM  +A++VT+ ++KQ LK+T+G+GT ATRASII+G 
Sbjct  474  NHVDLKALKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGL  533

Query  539  VDKGYFKRQKKVLLATDKAHALIAVLPPAIKSPGMTAAWEQELEKVASGSGNMSVFMKQI  598
            +++GY+ ++ + + A+D A  LI  +P+AI  PG TA WEQ L+ + +G   +  F+ + 
Sbjct  534  LERGYLLKKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQ  593

Query  599  STWICQMVEQLKVAAPVLTKEGGAMAKAFEGAKPPSHECFNCGGEMHRIKGKNGFFWG-C  657
            STWI Q+V+Q + A             ++    P +  C  CG+  ++  GK G FW+ C
Sbjct  594  STWITQLVQQYRAA-------------TLAIKLPEGPACPLCGSATRQRTGKTGPFWSCC  640

Query  658  QNEACKKTFPDNRGK  672
            +   CK T+P + G+
Sbjct  641  RYPDCKGTLPVQNGR  655


 Score = 47.1 bits (159),  Expect = 3e-06, Method: Compositional matrix adjust.
 Identities = 21/44 (48%), Positives = 29/44 (66%), Gaps = 6/44 (13%)

Query  683  PDCPDCGSPMRLRKGKAPGKKRASKFWGCTAYPDCKGTMPFKKS  726
            P CP CGS+ R R GK+      + FW+C  YPDCKGT+P +++
Sbjct  617  PACPLCGSATRQRTGKT------GPFWSCCRYPDCKGTLPVQNG  654

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  464 bits (1750),  Expect = 5e-132, Method: Compositional matrix adjust.
 Identities = 287/675 (43%), Positives = 449/675 (67%), Gaps = 23/675 (3%)

Query  1    MDLYICEKPSQAKDLAGVMKASQRGDGFLHDGGNRVITWAFGHLLELYMPDDYDERYKSW  60
            M L++CEKPSQ+KD+A V+ A+QRG G   +G+  V+TW +GHL+E   P+ Y+E+YK W
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGC-YNGAGTVVTWCIGHLIEAAPPEAYGEQYKRW  59

Query  61   SLETLPIAPESWRYNVRKSAFKQYKIVEGLVKKASTIYISTDYDREGEAIARSLLDRFRY  120
            SLE LPI PE WR + + ++  Q KIV  LV +AS + I+TD DREGE IAR ++D   Y
Sbjct  60   SLEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGY  119

Query  121  SGPIRRVCLTALDESSIKKALNNVKDGKDTVSLYYAALARQRADWLVGMNVSRLYTVLAR  180
             GPI+R+ L+AL+++SI+KAL  +K + ++++LY AALAR RADWLVGMN+SRL+T+L+R
Sbjct  120  RGPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGR  179

Query  181  DVGFNHTLHVGRVITPTVALVCQRDREIAGFTPSPYWTLGVNVSVQNGQFAAQWIPPEEC  240
            + G++  L VGRV TPT+ALV  RDREIA F + P+W++ V +S     F A WI+++ C
Sbjct  180  QAGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGC  239

Query  241  SDEQGRCVNKAYAEQVAS--QVNGANAVISKAETKPGKESAPLPFDLTSLQQYASKRWGY  298
            SD+ GRC+++A A+Q A   +V G+  V++   T   +E++PLPFDL +LQ+  S++ + 
Sbjct  240  SDDAGRCLQQATAQQAADRLRVAGSAQVVA-VTTERVREAPPLPFDLGTLQDVCSRQLAL  298

Query  299  TAQQVLDAAQALYETHKATTYPRTDSRYLPESQKEDIPDILQALILSDQNVSGLVAGADP  358
              Q+ LD AQALYETHKATTYPR+DS YLPES   ++P +L A++ +D ++  L+   D 
Sbjct  299  DVQETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDR  358

Query  359  HRKARVFNDAKVTAHHAIIPTPARTDISAMSEIEFNLYDAIRRFYIAQFYSEFEFTKTSI  418
             +++R  ND+KV+AHH+IIPT   ++++A+S+  + +Y  IR  Y+AQF +++EF +T+ 
Sbjct  359  TQRSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTA  418

Query  419  EVQCGRHLFAASGKTPAKQGWKVLFASDSESSPKDEGEDTDAPVEQEKLPRVSQGEPALL  478
            ++ CG + + A GK     GW  ++A     +P  +  D +A    + LP + +G +  +
Sbjct  419  QLLCGGQTLQAVGKQVIIPGWHQVLA-----GPEADNADGEAVPRSQVLPALREGLSCQV  473

Query  479  NGAELANKMTRPAPHFTEATLLAAMENIARFVTEEKFKQILKDTAGLGTPATRASIIQGA  538
            N  +L    T+P+  +T++ L+ AM  +A++VT+ ++KQ LK+T+G+GT ATRASII+G 
Sbjct  474  NHVDLKALKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGL  533

Query  539  VDKGYFKRQKKVLLATDKAHALIAVLPPAIKSPGMTAAWEQELEKVASGSGNMSVFMKQI  598
            +++GY+ ++ + + A+D A  LI  +P+AI  PG TA WEQ L+ + +G   +  F+ + 
Sbjct  534  LERGYLLKKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQ  593

Query  599  STWICQMVEQLKVAAPVLTKEGGAMAKAFEGAKPPSHECFNCGGEMHRIKGKNGFFWG-C  657
            STWI Q+V+Q + A             ++    P +  C  CG+  ++  GK G FW+ C
Sbjct  594  STWITQLVQQYRAA-------------TLAIKLPEGPACPLCGSATRQRTGKTGPFWSCC  640

Query  658  QNEACKKTFPDNRGK  672
            +   CK T+P + G+
Sbjct  641  RYPDCKGTLPVQNGR  655


 Score = 47.1 bits (159),  Expect = 3e-06, Method: Compositional matrix adjust.
 Identities = 21/44 (48%), Positives = 29/44 (66%), Gaps = 6/44 (13%)

Query  683  PDCPDCGSPMRLRKGKAPGKKRASKFWGCTAYPDCKGTMPFKKS  726
            P CP CGS+ R R GK+      + FW+C  YPDCKGT+P +++
Sbjct  617  PACPLCGSATRQRTGKT------GPFWSCCRYPDCKGTLPVQNG  654

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  456 bits (1719),  Expect = 1e-129, Method: Compositional matrix adjust.
 Identities = 293/659 (45%), Positives = 445/659 (68%), Gaps = 13/659 (1%)

Query  1    MRLFLCEKPSQAKDIASVLGC-KRGDGVFTGDGIAVTFCVGHVLQQAEPENYNPDFETWN  59
            MRLFLCEKPSQ+KDIA VLG  +RG G + G G  VT C+GH+++ A PE Y  ++  W+
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQYKRWS  60

Query  60   IVDLPIIPTVWKMLVSPKTKAQFAIVKKQLAKATEVIIATDADREGEVIAREVLEYVNYK  119
            + +LPIIP  W++   + T AQ+ IVK+ +++A+E++IATDADREGE+IARE+++   Y+
Sbjct  61   LEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGYR  120

Query  120  GPIQRLWLSALDDASIKKALASLRPNHETAKLYDAGLGRSRGDWLIGMNMTRLCTLLSRE  179
            GPIQRLWLSAL+DASI+KAL++L+P+ E+  LY A+L+RSR+DWL+GMN++RL TLL+R+
Sbjct  121  GPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGRQ  180

Query  180  YGYQGAFSVGRVQTPTLRLVVDRDRQVEQFEPQSYYDI-TGLFNATIPFKAKWQVPDNLG  238
             GY+G +SVGRVQTPTL LVV RDR++ +F + ++  I  GL  +  +F A W  +D  +
Sbjct  181  AGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGCS  240

Query  239  DEQGRCLQVTTVDHVLSQCR-DQPGTVTQFDTKRQKSKHPPLFFLGSLQKAMSAKFGYGA  297
            D+ GRCLQ +T ++   + R   ++ V    T R +   P  F LG+LQ   S +++ + 
Sbjct  241  DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALDV  300

Query  298  KEVLDIAQSLYEKYKVTTYPRTDCPYLPLSQKKEVGSIL-DKLKVVPTFAAWCSVADVNE  356
            +E LDIAQ+LYE  K TTYPR+D  YLP S   EV ++L   L   P++ +     D  +
Sbjct  301  QETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRTQ  360

Query  357  TSACWNDKKITAHHGIIPLPVTPKLHEMNEKELNLYHAIVQRYLAQFYPVAEDDATTIEL  416
             S  WND K++AHHGIIP    ++L  +++K L +Y+ I  +YLAQF P  E D TT +L
Sbjct  361  RSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQL  420

Query  417  MVGSQSFKATGKVERVKGWR-LVTGKDSEDETADDSSNLPLL-SIGQTLTAQFQRED---  471
            + G+Q+++A GK   + GW+ +++G ++++  ++  +   +L ++ + L+ Q ++ D   
Sbjct  421  LCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLSCQVNHVDLKA  480

Query  472  KRTKPPGRFTEGTLIDAMSNIAKFESDPKLKSILKETSGIGTEATRANIIDTLKARGFVT  531
             +T+PP  +T+G LI AM  +AK+ +DP+LK  LKET+GIGTEATRA+II  L  RG++ 
Sbjct  481  LKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERGYLL  540

Query  532  VTGKQLISSEAGRSLIDALPDVLTRPAMTALWEQALDEIALGNGSLDDFMARQSTFITQL  591
              G+ + +S+A+  LIDA+P  +T P+ TA+WEQALD I  G+ +L+ F+A+QST ITQL
Sbjct  541  KKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWITQL  600

Query  592  VSMFKQGQYTLKLPKVLAVTLPCPVCQKSMKQLSGKSGKFWVCEDKEQCGLLLNDERGK  650
            V  ++ +  ++KLP       +CP+C  + +Q +GK+G FW C    +C   L  + G+
Sbjct  601  VQQYRAATLAIKLPE----GPACPLCGSATRQRTGKTGPFWSCCRYPDCKGTLPVQNGR  655

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  456 bits (1717),  Expect = 2e-129, Method: Compositional matrix adjust.
 Identities = 284/675 (43%), Positives = 447/675 (67%), Gaps = 22/675 (3%)

Query  1    MDLYICEKPSQAKDLAGVLKLTQRGDGFIHDGGKRVITWAFGHLLEMYMPDDYDEKYKSW  60
            M L++CEKPSQ+KD+A VL   QRG G  +++G  V+TW +GHL+E   P+ Y+E+YK W
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGT-VVTWCIGHLIEAAPPEAYGEQYKRW  59

Query  61   SLDSLPIAPESWQSKVRQKSAKQYKIIEGLVKKASTVYISTDYDREGEAIARSLLDRFRY  120
            SL+ LPI PE W+   +  +A Q KI+  LV +AS + I+TD DREGE IAR ++D   Y
Sbjct  60   SLEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGY  119

Query  121  SGPVRRVCLTALDESSIRKALSNIKDGQDTVPLYYAALGRQRADWLIGMNVSRLYTVLAR  180
             GP++R+ L+AL+++SIRKAL+ +K + +++PLY AAL+R RADWL+GMN+SRL+T+L+R
Sbjct  120  RGPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGR  179

Query  181  QVGFESTLHVGRVITPTVALVCQRDRDIAGFTPSPYWVLGVNVAVQNGQFLAQWVPPEEC  240
            Q G+++ L VGRV TPT+ALV  RDR+IA F + P+W + V ++     FLA W++++ C
Sbjct  180  QAGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGC  239

Query  241  SDDQGRCTNKAYAEQVASQIN-GAQAVISKAETKPGKESAPLPFDLTALQQYGSKRWGYT  299
            SDD GRC ++A A+Q A ++  ++ A +    T   +E++PLPFDL +LQ+  S++ +  
Sbjct  240  SDDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALD  299

Query  300  AQQVLDAAQSLYETHKATTYPRTDSRYLPESQKENISDILQALILSDQRVSGLVAGADPH  359
             Q+ LD AQ+LYETHKATTYPR+DS YLPES   +++ +L A++ +D  +  L+   D  
Sbjct  300  VQETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRT  359

Query  360  RKARVFNDSKVSAHHAIIPTPARTNISAMSEIELNLYDAIRRFYIAQFYSEFEFSKTVIE  419
            +++R  NDSKVSAHH+IIPT   +N++A+S+  L +Y  IR  Y+AQF +++EF +T  +
Sbjct  360  QRSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQ  419

Query  420  VQSGRHLFAASGKTPTKQGWKVLFTSDSESDPKEEGEDVDALIEQEKLPRVSQGEPALLK  479
            +  G + + A GK     GW  ++++     P  +  D +A+   + LP + +G +  ++
Sbjct  420  LLCGGQTLQAVGKQVIIPGWHQVLAG-----PEADNADGEAVPRSQVLPALREGLSCQVN  474

Query  480  GADLANKMTRPAPHFTEATLLAAMENIARFVTEEKFKQILKDTAGLGTPATRASIIQGAV  539
              DL    T+P+  +T++ L+ AM  +A++VT+ ++KQ LK+T+G+GT ATRASII+G +
Sbjct  475  HVDLKALKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLL  534

Query  540  DKGYFKRQKKVLIATEKAHALIAVLPPAIKSPGMTAAWEQELEKIATGAGNMSVFMKQIS  599
            ++GY+ ++ + + A++ A  LI  +P+AI  PG TA WEQ L+ I +G   +  F+ + S
Sbjct  535  ERGYLLKKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQS  594

Query  600  SWICQMVEQLKTAAPALTQDGGAMVKAFAGAKPQLHVCFNCGGETLIRIKGKNGFFWG-C  658
            +WI Q+V+Q ++A+ A+    G+              C  CG+ T  R  GK G FW+ C
Sbjct  595  TWITQLVQQYRAATLAIKLPEGP-------------ACPLCGSATRQR-TGKTGPFWSCC  640

Query  659  KNEACKKTFPDNRGK  673
            +   CK T+P + G+
Sbjct  641  RYPDCKGTLPVQNGR  655


 Score = 44.0 bits (147),  Expect = 3e-05, Method: Compositional matrix adjust.
 Identities = 20/44 (46%), Positives = 28/44 (64%), Gaps = 6/44 (13%)

Query  684  PACPDCASPMRLRKGKAPGKVRATKFWGCTGYPDCKTTMPFKKS  727
            PACP C+S+ R R GK+        FW+C  YPDCK T+P +++
Sbjct  617  PACPLCGSATRQRTGKT------GPFWSCCRYPDCKGTLPVQNG  654

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  455 bits (1714),  Expect = 4e-129, Method: Compositional matrix adjust.
 Identities = 292/659 (45%), Positives = 442/659 (68%), Gaps = 13/659 (1%)

Query  1    MRLFLCEKPSQAKDIASVLGC-KRGDGVFTGDGIAVTFCVGHVLQQAEPENYNPDFETWN  59
            MRLFLCEKPSQ+KDIA VLG  +RG G + G G  VT C+GH+++ A PE Y  ++  W+
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQYKRWS  60

Query  60   IVDLPIIPTAWKMLVSPKTKAQFAIVKKQLAKATEVIIATDADREGEVIAREVLEYVNYK  119
            + +LPIIP  W++   + T AQ+ IVK+ +++A+E++IATDADREGE+IARE+++   Y+
Sbjct  61   LEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGYR  120

Query  120  GPIQRLWLSALDDASIKKALASLRPNHETAKLYDAGLGRSRGDWLIGMNMTRLCTLLSRE  179
            GPIQRLWLSAL+DASI+KAL++L+P+ E+  LY A+L+RSR+DWL+GMN++RL TLL+R+
Sbjct  121  GPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGRQ  180

Query  180  YGYQGAFSVGRVQTPTLRLVVDRDSQVEQFEPQSYYDI-TGLFNATIPFKAKWQVPDNLG  238
             GY+G +SVGRVQTPTL LVV RD ++ +F + ++  I  GL  +  +F A W  +D  +
Sbjct  181  AGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGCS  240

Query  239  DEQGRCLQVTTVDHVLSQCR-DQPGTVTQFDTKRQKSKHPPLFFLGSLQKAMSAKFGYGA  297
            D+ GRCLQ +T ++   + R   ++ V    T R +   P  F LG+LQ   S +++ + 
Sbjct  241  DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALDV  300

Query  298  KEVLDIAQSLYEKYKVTTYPRTDCPYLPLSQKEEVGSIL-DKLKVVPAFAAWCSAADVNE  356
            +E LDIAQ+LYE  K TTYPR+D  YLP S   EV ++L   L   P++ +     D  +
Sbjct  301  QETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRTQ  360

Query  357  TSACWNDKKITAHHGIIPLPVTPKLHEMNEKELNLYHAIVQRYLAQFYPVAEDDATTIEL  416
             S  WND K++AHHGIIP    ++L  +++K L +Y+ I  +YLAQF P  E D TT +L
Sbjct  361  RSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQL  420

Query  417  MVGSQSVKATGKVERVKGWR-LVTGKDSEDETTDDSANLPLL-SIGQTLTAQFQRED---  471
            + G+Q+++A GK   + GW+ +++G ++++   +  +   +L ++ + L+ Q ++ D   
Sbjct  421  LCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLSCQVNHVDLKA  480

Query  472  KRTKPPGRFTEGTLIDAMSNIAKFESDPKLKSILKETSGIGTEATRANIIDTLKARGFVT  531
             +T+PP  +T+G LI AM  +AK+ +DP+LK  LKET+GIGTEATRA+II  L  RG++ 
Sbjct  481  LKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERGYLL  540

Query  532  VTGKQLISSEAGRSLIDALPDVLTRPAMTALWEQALDEIALGNGSLDDFMARQSTFITQL  591
              G+ + +S+A+  LIDA+P  +T P+ TA+WEQALD I  G+ +L+ F+A+QST ITQL
Sbjct  541  KKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWITQL  600

Query  592  VSMFKQGQYTLKLPKVLAVTLPCPVCQKSMKQLSGKNGKFWVCEDKEQCGLLLNDERGK  650
            V  ++ +  ++KLP       +CP+C  + +Q +GK G FW C    +C   L  + G+
Sbjct  601  VQQYRAATLAIKLPE----GPACPLCGSATRQRTGKTGPFWSCCRYPDCKGTLPVQNGR  655

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  455 bits (1713),  Expect = 4e-129, Method: Compositional matrix adjust.
 Identities = 292/659 (45%), Positives = 442/659 (68%), Gaps = 13/659 (1%)

Query  1    MRLFLCEKPSQAKDIASVLGC-KRGDGVFTGDGIAVTFCVGHVLQQAEPENYNPDFETWN  59
            MRLFLCEKPSQ+KDIA VLG  +RG G + G G  VT C+GH+++ A PE Y  ++  W+
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQYKRWS  60

Query  60   IVDLPIIPTVWKMLVSPKTKAQFAIVKKQLAKATEVIIATDADREGEVIAREVLEYVNYK  119
            + +LPIIP  W++   + T AQ+ IVK+ +++A+E++IATDADREGE+IARE+++   Y+
Sbjct  61   LEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCGYR  120

Query  120  GPIQRLWLSALDDASIKKALASLRPNHETAKLYDAGLGRSRGDWLIGMNMTRLCTLLSRE  179
            GPIQRLWLSAL+DASI+KAL++L+P+ E+  LY A+L+RSR+DWL+GMN++RL TLL+R+
Sbjct  121  GPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLGRQ  180

Query  180  YGYQGAFSVGRVQTPTLRLVVDRDSQVEQFEPQSYYDI-TGLFNATIPFKAKWQVPDNLG  238
             GY+G +SVGRVQTPTL LVV RD ++ +F + ++  I  GL  +  +F A W  +D  +
Sbjct  181  AGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLATWIAADGCS  240

Query  239  DEQGRCLQVTTVDHVLSQCR-DQPGTVTQFDTKRQKSKHPPLFFLGSLQKAMSAKFGYGA  297
            D+ GRCLQ +T ++   + R   ++ V    T R +   P  F LG+LQ   S +++ + 
Sbjct  241  DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQLALDV  300

Query  298  KEVLDIAQSLYEKYKVTTYPRTDCPYLPLSQKEEVGSIL-DKLKVVPAFAAWCSAADVNE  356
            +E LDIAQ+LYE  K TTYPR+D  YLP S   EV ++L   L   P++ +     D  +
Sbjct  301  QETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQLDRTQ  360

Query  357  TSACWNDKKITAHHGIIPLPVTPKLHEMNEKELNLYHAIVQRYLAQFYPVAEDDATTIEL  416
             S  WND K++AHHGIIP    ++L  +++K L +Y+ I  +YLAQF P  E D TT +L
Sbjct  361  RSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYEFDRTTAQL  420

Query  417  MVGSQSVKATGKVERVKGWR-LVTGKDSEDETTDDSANLPLL-SIGQTLTAQFQRED---  471
            + G+Q+++A GK   + GW+ +++G ++++   +  +   +L ++ + L+ Q ++ D   
Sbjct  421  LCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLSCQVNHVDLKA  480

Query  472  KRTKPPGRFTEGTLIDAMSNIAKFESDPKLKSILKETSGIGTEATRANIIDTLKARGFVT  531
             +T+PP  +T+G LI AM  +AK+ +DP+LK  LKET+GIGTEATRA+II  L  RG++ 
Sbjct  481  LKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASIIKGLLERGYLL  540

Query  532  VTGKQLISSEAGRSLIDALPDVLTRPAMTALWEQALDEIALGNGSLDDFMARQSTFITQL  591
              G+ + +S+A+  LIDA+P  +T P+ TA+WEQALD I  G+ +L+ F+A+QST ITQL
Sbjct  541  KKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFVAKQSTWITQL  600

Query  592  VSMFKQGQYTLKLPKVLAVTLPCPVCQKSMKQLSGKNGKFWVCEDKEQCGLLLNDERGK  650
            V  ++ +  ++KLP       +CP+C  + +Q +GK G FW C    +C   L  + G+
Sbjct  601  VQQYRAATLAIKLPE----GPACPLCGSATRQRTGKTGPFWSCCRYPDCKGTLPVQNGR  655

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  430 bits (1618),  Expect = 1e-121, Method: Compositional matrix adjust.
 Identities = 274/678 (41%), Positives = 437/678 (65%), Gaps = 37/678 (5%)

Query  1    MRLFLCEKPSQAKDIGKVLGVLGGRHDGYFQNGDTIVTWAFGHILTQAAPDAYGEQYADF  60
            MRLFLCEKPSQ+KDI++VLG  G R  G ++ ++T+VTW +GH++  A+P+AYGEQY   
Sbjct  1    MRLFLCEKPSQGKDIARVLGA-GQRGSGCYNGAGTVVTWCIGHLIEAAPPEAYGEQYKRW  59

Query  61   GNISALPILPEVWQMQVPPKVSKQFKVIKSLLAKADEVVIATDADREGEVIAREILDYCG  120
             ++  LPI+PE W+++  +  + Q+K++K L+++A E+VIATDADREGE+IAREI+D CG
Sbjct  60   -SLEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCG  118

Query  121  YRKKISRFWTSGLDTQSVKKALSSIMPGKDKENLYQAGLARGRADWLVGMNLSRAYT-AA  179
            YR  I R+W S+L+  S++KAL+++ P+ +   LY A+LAR+RADWLVGMNLSR +T  +
Sbjct  119  YRGPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTLLG  178

Query  180  YSAGYGREHILSIGRIQTPTLKLVVQRDKEIDTFVPYNYYTLSVDFETADKSVFTTLWQV  239
              AGY  + +LS+GR+QTPTL LVV RD+EI  FV+  + ++ V++ T++ S F + W  
Sbjct  179  RQAGY--DGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHS-FLATWIA  235

Query  240  PENWRNTDGYCTNLEAVKALVKQLE-KSTGKVITSNKERKSTPPPLPYSLSALQKEAGKK  298
            ++   +  G C +  + +    +L   ++++V++   ER   +PPLP+ L++LQ   +++
Sbjct  236  ADGCSDDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVCSRQ  295

Query  299  LGLSASKVLKIAQTLYEKYKITSYPRTPCRYLPKSQMSEVKDVFAAIQTIDKSMLSVIEK  358
            L+L     L IAQ+LYE  K T+YPR+   YLP S ++EV  V+AA+ T D S+ +++E+
Sbjct  296  LALDVQETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPLLEQ  355

Query  359  ADPERQSRVWNDNQVNKHSHHAIIPTKASNFDLSVLDKNELTVYRMIRDRYIAQFYPDFE  418
             D  ++SR WND++V+  +HH+IIPT  +  +L+ +  + L+VYR+IR +Y+AQF P++E
Sbjct  356  LDRTQRSRAWNDSKVS--AHHGIIPTLEPA-NLAAISDKALAVYRLIRAHYLAQFLPHYE  412

Query  419  YDSTVVEVEACSHLFKASSQSPVISGWKVLLG---KDVFEGDQIDEGPALPHLKVNDEVD  475
            +D T  ++   ++ ++A ++  +I+GW  +L+    D  +G+ +  +  LP L+     +
Sbjct  413  FDRTTAQLLCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLSCQ  472

Query  476  TLSFNPETKKTTPPPRFTEASLLDEMQTLKDFLKNVEDEQIRKILKSTEGLGTEATRATI  535
                +  + KT PP  +T++ L+  M   K+  K V D ++++ LK T G+GTEATRA+I
Sbjct  473  VNHVDLKALKTQPPKPYTQGDLIKAM---KGVAKLVTDPRLKQKLKETTGIGTEATRASI  529

Query  536  IDRLFEMGYMEKKRSKIYATEKGRNLIARIPTMIADPITTAKWELALAGIEAGKLTLAEF  595
            I  L+E GY+ KK   + A++ +  LI  +P+ I+DP TTA WE AL  IEAG +TL  F
Sbjct  530  IKGLLERGYLLKKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETF  589

Query  596  MAYQQKVITELVGQAKKDAVGKARPPKQTDSAGTKKQAVARNEDDVCPTCKEGRLRQRGF  655
            +A Q   IT+LV Q +  ++                 A+   E+  CP C  +  RQR  
Sbjct  590  VAKQSTWITQLVQQYRAATL-----------------AIKLPEGPACPLCGSAT-RQRTG  631

Query  656  KENPDKRYWGCSRFPECK  673
            K  P   +W+C R+P+CK
Sbjct  632  KTGP---FWSCCRYPDCK  646

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  409 bits (1539),  Expect = 2e-115, Method: Compositional matrix adjust.
 Identities = 251/620 (41%), Positives = 415/620 (67%), Gaps = 20/620 (3%)

Query  1    MRLYIAEKPSLGRAIADVLPKPHKKGDGFITAANGDCVSWCIGHLLEQAEPDAYDVAFKS  60
            MRL++ EKPS G+ IA VL   ++ ++ +   + G  V+WCIGHL+E A P+AY+  +K 
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCY--NGAGTVVTWCIGHLIEAAPPEAYGEQYKR  58

Query  61   WKLEHLPIIPTQWQLKPKSSTRSQLSVLKKLVKQATHLVNAGDPDREGQLLVDEVIAYLG  120
            W LE+LPIIP +W++ PK++T +QL ++K+LV QA++LV A D+DREG+++  E+I   G
Sbjct  59   WSLEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCG  118

Query  121  VKGDKLNQVQRLLISDLNPQAVQRALNQLKSNRDFIPLSTSALARSRADWLYGMNMTRAY  180
             +G     +QRL +S LN  ++++AL  LK++ + +PL ++ALARSRADWL GMN++R +
Sbjct  119  YRG----PIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLF  174

Query  181  TIQGKKVGYQGVLSVGRVQTPLLGLVVRRDEEIEAFVPKPFYEVLAHLLTDKQQGFTAKW  240
            T+ G++ GY+GVLSVGRVQTP L+LVV RD EI  FV+ PF  +   L T+  ++F A W
Sbjct  175  TLLGRQAGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTG-GHSFLATW  233

Query  241  QPSAACEPYQDEEGRVLVKGLGQNVVERIS-GQPAQVTGLVAQDKRQAAPLPYSLSSLQI  299
             ++ +C    D+ GR L ++ +Q+  +R+  + +AQV ++ ++  R+A+PLP+ L++LQ 
Sbjct  234  IAADGCS---DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQD  290

Query  300  DAAKRFGLSAKEVLDTCQSLYERHKLITYPRSDSRHLPVEQFSLAPSVINAVIKGAPTLI  359
              +++++L  +E LD  Q+LYE HK  TYPRSDS  LP   ++  P+V+ A++   P+L 
Sbjct  291  VCSRQLALDVQETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLR  350

Query  360  SHTDAPNPKLKSKAWDDSKVEAHHAIIPTEKIAHLSALSMNEARLYQHIARQYLAQFYPA  419
            +  +  +   +S+AW+DSKV AHH+IIPT   A+L+A+S +   +Y+ I  +YLAQF P 
Sbjct  351  PLLEQLDRTQRSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPH  410

Query  420  YQYAETQVEVTIAGGIFTTKARQNKSLGWKSLFSNNNKIVEHNTENNQEGEPESQTLPAL  479
            Y++  T  ++  +G  + + ++Q    GW  +++  +       + + E+ P SQ LPAL
Sbjct  411  YEFDRTTAQLLCGGQTLQAVGKQVIIPGWHQVLAGPE-----ADNADGEAVPRSQVLPAL  465

Query  480  KKGQWLNCE--RGELLEKMTQAPKHFSDASLLSAMTGIGRFVTNVEIKKILKDTDGIGTE  537
            + G  L+C+  + +L    TQ+PK ++++ L+ AM G++++VT+  +K+ LK+T GIGTE
Sbjct  466  REG--LSCQVNHVDLKALKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTE  523

Query  538  ATRAGIIELLFKRGYLLRQGKSILATPVGRGLINSLPMSATTPDMTALWEASLDKISHKT  597
            ATRA+II  L+ RGYLL++G+++ A+  +  LI+++P + T P+ TA+WE +LD I    
Sbjct  524  ATRASIIKGLLERGYLLKKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGD  583

Query  598  MRYQAFMAPLIQQLSELIGQ  617
            M  ++F+A     +++L+ Q
Sbjct  584  MTLETFVAKQSTWITQLVQQ  603

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  403 bits (1516),  Expect = 2e-113, Method: Compositional matrix adjust.
 Identities = 246/613 (41%), Positives = 402/613 (66%), Gaps = 11/613 (1%)

Query  1    MILYIAEKPSLGRAIADVLPKPHKKGEGYITAANGDTVSWCIGHLLEQAEPDSYDPAFKS  60
            M L++ EKPS G+ IA VL   ++ +  Y   + G  V+WCIGHL+E A P++Y+  +K 
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCY--NGAGTVVTWCIGHLIEAAPPEAYGEQYKR  58

Query  61   WSFDHLPIVPQQWKMTPKSKTRGQLSVLRKLVKQASQLVNAGDPDREGQLLVDEVIAYLG  120
            WS+++LPI+P++W++ PK+ T +QL ++++LV QAS+LV A D+DREG+++  E+I   G
Sbjct  59   WSLEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCG  118

Query  121  VKGDKLEQTQRLLVSDLNPQAVKRALGQLRSNREFIPLSTSALARSRADWLYGMNMTRAY  180
             +G      QRL +S LN  ++++ALG L+++ E +PL ++ALARSRADWL GMN++R +
Sbjct  119  YRG----PIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLF  174

Query  181  TLQGRKVGYQGVLSVGRVQTPLLGLVVRRDEAIEHFVSKPFYEVLANLYTQEQAHFKAKW  240
            TL GR+ GY+GVLSVGRVQTP L+LVV RD  I +FVS PF  +   L T  ++ F A W
Sbjct  175  TLLGRQAGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHS-FLATW  233

Query  241  QPSEACQPYMDEEGRVLSRRLAENVVGRI-TEQPAKVTDLQAKDKQQGQPLPYNLSSLQI  299
             ++++C    D+ GR L +  A++  +R+    +A+V  + +   +++ PLP++L++LQ 
Sbjct  234  IAADGCS---DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQD  290

Query  300  DAAKRFGMSAKTVLDTCQSLYEKHKLITYPRSDSRYLPKEQLALAPSVIGAVLKGAGELT  359
              ++++++  +  LD  Q+LYE HK  TYPRSDS YLP   LA  P+V++A+L     L 
Sbjct  291  VCSRQLALDVQETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLR  350

Query  360  AQCAAPDLKIVSKAWNDAKVDAHHAIVPTEKVANLSALTQAEKQIYLQLARQYLAQFYPV  419
            +     D    S+AWND+KV AHH+I+PT   ANL+A+++    +Y  +  +YLAQF P 
Sbjct  351  PLLEQLDRTQRSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPH  410

Query  420  YRYHETQVEVEIAGGHFHTKAKQEIALGWKQLFPKRSDDKTDGEGDEALAQLPPLHKGQM  479
            Y ++ T  ++  +G  +++ +KQ I  GW Q+++    D++DGE+      LP+L+ G  
Sbjct  411  YEFDRTTAQLLCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLS  470

Query  480  LHSGQGELIEKQTQPPKAFTDATLLSAMTGISRYVTNPEIRKILKETDGLGTEATRAGII  539
             +  + +L   +TQPPK++T++ L+ AM G+++ VT+P +++ LKET G+GTEATRA+II
Sbjct  471  CQVNHVDLKALKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASII  530

Query  540  ELLFKRGFLARQGKSIVSTPVGRGLINSLPESATTPDMTALWESHLDAISRKEAKYLSFM  599
              L+ RG+L ++G+++ ++  +  LI+++P + T P+ TA+WE  LD I   +    +F+
Sbjct  531  KGLLERGYLLKKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFV  590

Query  600  APLVESLNGLIMQ  612
            A     +  L+ Q
Sbjct  591  AKQSTWITQLVQQ  603

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  396 bits (1488),  Expect = 2e-111, Method: Compositional matrix adjust.
 Identities = 250/618 (41%), Positives = 410/618 (67%), Gaps = 19/618 (3%)

Query  1    MRLFIAEKPSLGRAIADVLPKPHKKGEGFIETAQGDVVTWCIGHLLEQAEPDAYDAAYKQ  60
            MRLF+ EKPS G+ IA VL   ++ +  +   + G VVTWCIGHL+E A P+AY+  YK+
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCY--NGAGTVVTWCIGHLIEAAPPEAYGEQYKR  58

Query  61   WRMESLPIVPAQWQLVAKPKTKTQLTVIKRLLKQADCVVNAGDPDREGQLLVDEVIDFLG  120
            W +E LPI+P +W++ +K+ T +QL ++K+L+ QA  +V A D+DREG+++  E+ID+ G
Sbjct  59   WSLEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCG  118

Query  121  YGKTRPVLRCLISDLNPPAVRRALDKLRDNKEFVPLAVSALARSRADWLYGINMTRAYTL  180
            Y      L+  +S LN +++R+AL+ L+ + E +PL  +ALARSRADWL G+N++R +TL
Sbjct  119  YRGPIQRLW--LSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTL  176

Query  181  LGRKGGCSELLSVGRVQTPLLGLVVRRDLEIEAFVPKPFFEVLAHLQTEGNEHFSAKWLP  240
            LGR++G   +LSVGRVQTP L+LVV RD EI  FV+ PF  +   L T G+  F A W++
Sbjct  177  LGRQAGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHS-FLATWIA  235

Query  241  SEACLPWQDEEGRVLNRALAAKVVERIQ-GQPALVEEVEEQARKQAAPLPYNLSSLQIDA  299
            +++C    D+ GR L++A A +  +R++ + +A V  V  +  ++A+PLP++L++LQ   
Sbjct  236  ADGC---SDDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVC  292

Query  300  AKRFGMDAKRVLDVCQGLYERHKLITYPRSDSRHLPSDHFNRAGQVREAIASTAPALAKA  359
            ++++++D +  LD+ Q+LYE HK  TYPRSDS  LP   +     V  A+ +T P+L   
Sbjct  293  SRQLALDVQETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPL  352

Query  360  VSEADGKIRSKAWNDSKVDAHHAIIPTEKQGNPATLGADEAKLYGLIARQYLLQFYPPFE  419
            + + D   RS+AWNDSKV AHH+IIPT   +N A+++     +Y LI  +YL QF P +E
Sbjct  353  LEQLDRTQRSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYE  412

Query  420  YNDSKVLLRIAGGLFQAKARRILKAGWKALLGVEEDDEEEAGT------LPALRKGEQLL  473
            ++ +   L  +G  +QA +++++ +GW  +L+  E D+ ++ +      LPALR G  L 
Sbjct  413  FDRTTAQLLCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREG--LS  470

Query  474  CE--RGELQEKMTQPPKSFTDATLLAAMTGIARYVQDPEIRKTLRETDGLGTEATRAGII  531
            C+  + +L+   TQPPK++T++ L+ AM G+A+ V DP +++ L+ET G+GTEATRA+II
Sbjct  471  CQVNHVDLKALKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASII  530

Query  532  DLLFKRRFLVRQGKSIKATPTGRALIQALPATATTPDMTALWEQHLGRIAERQTSYQQFM  591
              L+ R +L+++G++++A+ ++  LI+A+PA+ T P+ TA+WEQ L+ I   + + + F+
Sbjct  531  KGLLERGYLLKKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFV  590

Query  592  GPLTEQLNGLIDGARQDS  609
            +  +  +  L++  R  +
Sbjct  591  AKQSTWITQLVQQYRAAT  608

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  395 bits (1486),  Expect = 4e-111, Method: Compositional matrix adjust.
 Identities = 251/618 (41%), Positives = 418/618 (68%), Gaps = 18/618 (2%)

Query  1    MRLFIAEKPTLGRAIADALPKPHKKGDGFIETAQGDVVTWCIGHLLEQAEPDAYDAAFKQ  60
            MRLF+ EKP+ G+ IA  L   ++ ++ +   + G VVTWCIGHL+E A P+AY+  +K+
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCY--NGAGTVVTWCIGHLIEAAPPEAYGEQYKR  58

Query  61   WRMEHLPIIPAQWQLVAKPKTKTQLTVIKRLIKQADCVVNAGDPDREGQLLVDEVIDFLG  120
            W +E+LPIIP +W++ +K+ T +QL ++K+L+ QA  +V A D+DREG+++  E+ID+ G
Sbjct  59   WSLEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCG  118

Query  121  YPKTKPVQRCLISDLNPPAVRRALDKLRDNKEFVPLAVSALARSRADWLYGINMTRAYTL  180
            Y    P+QR  +S LN +++R+AL+ L+ + E +PL  +ALARSRADWL G+N++R +TL
Sbjct  119  YRG--PIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLFTL  176

Query  181  LGRKAGCSELLSVGRVQTPLLGLVVRRDLEIEAFVPKPFYEVLAHLLTEGNERFTAKWLP  240
            LGR+AG   +LSVGRVQTP L+LVV RD EI  FV+ PF  +   L + G + F A W++
Sbjct  177  LGRQAGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGL-STGGHSFLATWIA  235

Query  241  SEACLPWQDEEGRVLNRALADKVVSRIN-GQPAQVESVEEQARKQAAPLPYNLSSLQIDA  299
            +++C    D+ GR L++A A++   R+  + +AQV +V  +  ++A+PLP++L++LQ   
Sbjct  236  ADGC---SDDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQDVC  292

Query  300  AKRFGMDAKRVLDICQSLYERHKLITYPRSDSRYLPTDHFKRAEQVRGaiaatapalaka  359
            ++++++D +  LDI Q+LYE HK  TYPRSDS YLP   +     V +A+ +T P+L   
Sbjct  293  SRQLALDVQETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLRPL  352

Query  360  VSEADGKIRSKAWNDSKVDAHHAIIPTEKQGNPATLGADEAKLYGLIARQYLLQFYPPFE  419
            + + D   RS+AWNDSKV AHH+IIPT   +N A+++     +Y LI  +YL QF P +E
Sbjct  353  LEQLDRTQRSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPHYE  412

Query  420  YNDSKVLLRIAGGLFQAKARRILKAGWKALLGVEEDDDEE-----KAGTLPALKEGEQLL  474
            ++ +   L  +G  +QA +++++ +GW  +L+  E D+ +     ++  LPAL+EG  L 
Sbjct  413  FDRTTAQLLCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREG--LS  470

Query  475  CE--RGELQEKMTQPPKSFTDATLLAAMTGIARYVQDPEIRKTLRDTDGLGTEATRAGII  532
            C+  + +L+   TQPPK++T++ L+ AM G+A+ V DP +++ L++T G+GTEATRA+II
Sbjct  471  CQVNHVDLKALKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASII  530

Query  533  DLLFKRRFLVRQGKSIKATPTGRALVQALPATATTPDMTALWEQSLGQIAERHGSYQQFM  592
              L+ R +L+++G++++A+ ++  L++A+PA+ T P+ TA+WEQ+L+ I   + + + F+
Sbjct  531  KGLLERGYLLKKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFV  590

Query  593  GPLTEQLNGLIEGARQDS  610
            +  +  +  L++  R  +
Sbjct  591  AKQSTWITQLVQQYRAAT  608

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  389 bits (1462),  Expect = 3e-109, Method: Compositional matrix adjust.
 Identities = 264/618 (43%), Positives = 398/618 (65%), Gaps = 28/618 (4%)

Query  1    MRLFVAEKPSLARAIADVLPKPHQRGDGFIKC--GKNDCVTWCVGHLLEQAEPDAYNPMF  58
            MRLF+ EKPS ++ IA VL  + QRG G   C  G    VTWC+GHL+E A P+AY   +
Sbjct  1    MRLFLCEKPSQGKDIARVLG-AGQRGSG---CYNGAGTVVTWCIGHLIEAAPPEAYGEQY  56

Query  59   KQWRLEHLPIVPKKWRLIPRKEVAKQLKTVENLIHQADQLVNAGDPDREGQLLVDEVFNY  118
            K+W LE+LPI+P +WR+ P+   A QLK V +L+ QA +LV A D+DREG+++  E+++ 
Sbjct  57   KRWSLEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDL  116

Query  119  ANLSTDKRNAIQRCLVSDLNPAAVEKAVKKLQPNTNFIPLATSALARARADWLYGINMTR  178
                   R +IQR  +S LN A++ KA+  L+P+++ +PL ++ALAR+RADWL G+N++R
Sbjct  117  CGY----RGPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSR  172

Query  179  AYTIRGRQAGYNGVLSVGRVQTPVLGLIVRRDLEIENFQPKDFFEVLAHIQTEDETPQKF  238
             +T+ GRQAGY+GVLSVGRVQTP L+L+V RD EI  F +  F  +   + T +   + F
Sbjct  173  LFTLLGRQAGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGG---HSF  229

Query  239  TALWQPSKACEDYQDDDGRVLSLGLAENVVKRI-TGQPAEVTEYTDKREKETAPLPYSLS  297
             A W ++ +C D   D GR L  + A++   R+  + +A+V   T  R +E++PLP+ L+
Sbjct  230  LATWIAADGCSD---DAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLG  286

Query  298  ALQIDAAKRFAMSAQDVLDTCQRLYETHKLITYPRSDCRYLPNEHFAERMPVLNAISTHC  357
            +LQ   ++++A+  Q+ LD  Q LYETHK  TYPRSD  YLP+  +AE  +VL A+ T  
Sbjct  287  TLQDVCSRQLALDVQETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTD  346

Query  358  KEYQPLPEVLNTEQKNRCWNDKKVEAHHAIIPT-AKNRPVNLNSQELNIYTLIARQYLMQ  416
               +PL E L+  Q++R WND KV AHH+IIPT        ++ + L +Y LI  +YL Q
Sbjct  347  PSLRPLLEQLDRTQRSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQ  406

Query  417  FCPDAEYRKSKISLKIAGGNFVAQARNLQIAGWKELL-GKEDENEQLEPS-----LPIVK  470
            F P+ E+ ++   L  +G  + A ++++ I+GW ++L G E +N + E+      LP ++
Sbjct  407  FLPHYEFDRTTAQLLCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALR  466

Query  471  KGQQLFCEKGEVISK--KTQPPKPFTDVTLLSAMTGIARFVQDKELKKILRETDGLGTEA  528
             G  L C+  +V  K  KTQPPKP+T+  L+ AM G+A++V D  LK+ L+ET G+GTEA
Sbjct  467  EG--LSCQVNHVDLKALKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEA  524

Query  529  TRAGIIELLFKRGFLYKKGRNIHSSEAGRILIQALPDMATQPDMTAQWEAQLDGISRKQA  588
            TRA+II  L+ RG+L KKGR +++S+A+  LI+A+P   T+P+ TA WE  LD I   + 
Sbjct  525  TRASIIKGLLERGYLLKKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDM  584

Query  589  SYQQFMATLTELLPELVQ  606
            + + F+A  +  + +LVQ
Sbjct  585  TLETFVAKQSTWITQLVQ  602

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  388 bits (1458),  Expect = 6e-109, Method: Compositional matrix adjust.
 Identities = 250/615 (41%), Positives = 412/615 (67%), Gaps = 18/615 (2%)

Query  1    MRLFIAEKPSLARAIADVLPKPHRRGDGYIACGSDQVVTWCVGHLLEQAQPDSYNSRFAR  60
            MRLF+ EKPS ++ IA VL   +R ++ Y   G++ VVTWC+GHL+E A P++Y  ++ R
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYN--GAGTVVTWCIGHLIEAAPPEAYGEQYKR  58

Query  61   WSLDDLPIVPEKWRLQPRPSVAKQLNVIKGLLAQASVVVHAGDPDREGQLLVDEVLDYLT  120
            WSL++LPI+PE+WR++P+++ A QL+++K L++QAS +V A D+DREG+++  E++D   
Sbjct  59   WSLEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDL--  116

Query  121  LPAEKRAQVQRCLINDLNPQAVERAIGRLRENREFIPLCVSALARARADWLYGINMTRAY  180
                 R+ +QR  ++ LN  ++ +A+G L+ + E +PL  +ALAR+RADWL G+N++R +
Sbjct  117  --CGYRGPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLF  174

Query  181  TLLGRNAGYDGVLSVGRVQTPVLGLVVRRDEEIENFVAKDFFEVRAHIVTPADERFVALW  240
            TLLGR+AGYDGVLSVGRVQTP L+LVV RD EI  FV+  F  +   + T +++ F+A W
Sbjct  175  TLLGRQAGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLST-GGHSFLATW  233

Query  241  QPSASCEPYQDEEGRLLHRPLAEHVVARI-GGHPAHVTSYNDKRENETAPLPFSLSALQI  299
             ++ +C    D+ GR L+++ A++   R+  + +A+V +    R  E++PLPF L++LQ 
Sbjct  234  IAADGCS---DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQD  290

Query  300  EAGKRFGLSAQTVLDTCQRLYETHKLITYPRSDSRYLPDEHFAGRHAVLNAINVHQPNLS  359
              +++++L  Q  LD  Q LYETHK  TYPRSDS YLP+  +A   AVL A+   +P+L 
Sbjct  291  VCSRQLALDVQETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLR  350

Query  360  P-PGDFNSDQKNRCWDDKKVDAHHAIIPTARSSQV-SLSDNEQQIYRLIATQYLMQFCPD  417
            P   +++  Q++R W+D KV AHH+IIPT  ++++ ++SD+   +YRLI ++YL QF P+
Sbjct  351  PLLEQLDRTQRSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPH  410

Query  418  AVYRKCVIELDIAGGKFVAKARFLAEAGWRALLGSKERDE-ENDGTPLPVVTKG--DELL  474
              + +   +L  +G  + A ++ +  +GW+ +L++ E D+ + ++ P + V  +  + L 
Sbjct  411  YEFDRTTAQLLCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLS  470

Query  475  CERGEVQEK--QTQPPRPFTDATLLSAMTGIARFVQDKDLKKVLRATDGLGTEATRAGII  532
            C+  +V+ K  +TQPP+P+T++ L+ AM G+A++V D  LK+ L+ T G+GTEATRA+II
Sbjct  471  CQVNHVDLKALKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASII  530

Query  533  ELLFKRTFLFKKGRYIHSSPAGRALIHSLPEMAARPDMTAHWESTLTKISEKQCRYQDFM  592
              L+ R +L+KKGR +++S A+  LI+++P   + P+ TA WE +L  I   +   + F+
Sbjct  531  KGLLERGYLLKKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFV  590

Query  593  SPLVDTLHSLIQQAR  607
            +     +  L+QQ R
Sbjct  591  AKQSTWITQLVQQYR  605

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  388 bits (1458),  Expect = 6e-109, Method: Compositional matrix adjust.
 Identities = 250/615 (41%), Positives = 412/615 (67%), Gaps = 18/615 (2%)

Query  1    MRLFIAEKPSLARAIADVLPKPHRRGDGYIACGSDQVVTWCVGHLLEQAQPDSYNSRFAR  60
            MRLF+ EKPS ++ IA VL   +R ++ Y   G++ VVTWC+GHL+E A P++Y  ++ R
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYN--GAGTVVTWCIGHLIEAAPPEAYGEQYKR  58

Query  61   WSLDDLPIVPEKWRLQPRPSVAKQLNVIKGLLAQASVVVHAGDPDREGQLLVDEVLDYLT  120
            WSL++LPI+PE+WR++P+++ A QL+++K L++QAS +V A D+DREG+++  E++D   
Sbjct  59   WSLEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDL--  116

Query  121  LPAEKRAQVQRCLINDLNPQAVERAIGRLRENREFIPLCVSALARARADWLYGINMTRAY  180
                 R+ +QR  ++ LN  ++ +A+G L+ + E +PL  +ALAR+RADWL G+N++R +
Sbjct  117  --CGYRGPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLF  174

Query  181  TLLGRNAGYDGVLSVGRVQTPVLGLVVRRDEEIENFVAKDFFEVRAHIVTPADERFVALW  240
            TLLGR+AGYDGVLSVGRVQTP L+LVV RD EI  FV+  F  +   + T +++ F+A W
Sbjct  175  TLLGRQAGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLST-GGHSFLATW  233

Query  241  QPSASCEPYQDEEGRLLHRPLAEHVVARI-GGHPAHVTSYNDKRENETAPLPFSLSALQI  299
             ++ +C    D+ GR L+++ A++   R+  + +A+V +    R  E++PLPF L++LQ 
Sbjct  234  IAADGCS---DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQD  290

Query  300  EAGKRFGLSAQTVLDTCQRLYETHKLITYPRSDSRYLPDEHFAGRHAVLNAINVHQPNLS  359
              +++++L  Q  LD  Q LYETHK  TYPRSDS YLP+  +A   AVL A+   +P+L 
Sbjct  291  VCSRQLALDVQETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLR  350

Query  360  P-PGDFNSDQKNRCWDDKKVDAHHAIIPTARSSQV-SLSDNEQQIYRLIATQYLMQFCPD  417
            P   +++  Q++R W+D KV AHH+IIPT  ++++ ++SD+   +YRLI ++YL QF P+
Sbjct  351  PLLEQLDRTQRSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPH  410

Query  418  AVYRKCVIELDIAGGKFVAKARFLAEAGWRALLGSKERDE-ENDGTPLPVVTKG--DELL  474
              + +   +L  +G  + A ++ +  +GW+ +L++ E D+ + ++ P + V  +  + L 
Sbjct  411  YEFDRTTAQLLCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLS  470

Query  475  CERGEVQEK--QTQPPRPFTDATLLSAMTGIARFVQDKDLKKVLRATDGLGTEATRAGII  532
            C+  +V+ K  +TQPP+P+T++ L+ AM G+A++V D  LK+ L+ T G+GTEATRA+II
Sbjct  471  CQVNHVDLKALKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASII  530

Query  533  ELLFKRTFLFKKGRYIHSSPAGRALIHSLPEMAARPDMTAHWESTLTKISEKQCRYQDFM  592
              L+ R +L+KKGR +++S A+  LI+++P   + P+ TA WE +L  I   +   + F+
Sbjct  531  KGLLERGYLLKKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFV  590

Query  593  SPLVDTLHSLIQQAR  607
            +     +  L+QQ R
Sbjct  591  AKQSTWITQLVQQYR  605

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  387 bits (1455),  Expect = 9e-109, Method: Compositional matrix adjust.
 Identities = 249/615 (41%), Positives = 411/615 (67%), Gaps = 18/615 (2%)

Query  1    MRLFIAEKPSLARAIADVLPKPHRRGDGYIACGSDQVVTWCVGHLLEQAQPDSYNSRFAR  60
            MRLF+ EKPS ++ IA VL   +R ++ Y   G++ VVTWC+GHL+E A P++Y  ++ R
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYN--GAGTVVTWCIGHLIEAAPPEAYGEQYKR  58

Query  61   WSLDDLPIVPEKWRLQPRPSVAKQLNVIKGLLTQASVVVHAGDPDREGQLLVDEVLDYLT  120
            WSL++LPI+PE+WR++P+++ A QL+++K L+ QAS +V A D+DREG+++  E++D   
Sbjct  59   WSLEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDL--  116

Query  121  LPAEKRAQVQRCLINDLNPQAVERAIGRLRENREFIPLCVSALARARADWLYGINMTRAY  180
                 R+ +QR  ++ LN  ++ +A+G L+ + E +PL  +ALAR+RADWL G+N++R +
Sbjct  117  --CGYRGPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLF  174

Query  181  TLLGRNAGYDGVLSVGRVQTPVLGLVVRRDEDIENFVAKDFFEVRAHIVTPADERFVALW  240
            TLLGR+AGYDGVLSVGRVQTP L+LVV RD +I  FV+  F  +   + T +++ F+A W
Sbjct  175  TLLGRQAGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLST-GGHSFLATW  233

Query  241  QPSASCEPYQDEEGRLLHRPLAEHVVARI-GGQPAHVTSYNDKRENETAPLPFSLSALQI  299
             ++ +C    D+ GR L+++ A++   R+  + +A+V +    R  E++PLPF L++LQ 
Sbjct  234  IAADGCS---DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQD  290

Query  300  EAGKRFGLSAQTVLDTCQRLYETHKLITYPRSDSRYLPDEHFAGRHAVLNAINVHQPNLS  359
              +++++L  Q  LD  Q LYETHK  TYPRSDS YLP+  +A   AVL A+   +P+L 
Sbjct  291  VCSRQLALDVQETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLR  350

Query  360  P-PGDFNSDQKNRCWDDKKVDAHHAIIPTARSSQV-SLSDNEQQIYRLIATQYLMQFCPD  417
            P   +++  Q++R W+D KV AHH+IIPT  ++++ ++SD+   +YRLI ++YL QF P+
Sbjct  351  PLLEQLDRTQRSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPH  410

Query  418  AVYRKCVIELDIAGGKFVAKARFLAEAGWRALLGSKERDE-ENDGTPLPVVTKG--DELL  474
              + +   +L  +G  + A ++ +  +GW+ +L++ E D+ + ++ P + V  +  + L 
Sbjct  411  YEFDRTTAQLLCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLS  470

Query  475  CERGEVQEK--QTQPPRPFTDATLLSAMTGIARFVQDKDLKKVLRATDGLGTEATRAGII  532
            C+  +V+ K  +TQPP+P+T++ L+ AM G+A++V D  LK+ L+ T G+GTEATRA+II
Sbjct  471  CQVNHVDLKALKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASII  530

Query  533  ELLFKRTFLFKKGRYIHSSPAGRALIHSLPEMAARPDMTAHWESTLTKISEKQCRYQDFM  592
              L+ R +L+KKGR +++S A+  LI+++P   + P+ TA WE +L  I   +   + F+
Sbjct  531  KGLLERGYLLKKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFV  590

Query  593  SPLVDTLHSLIQQAR  607
            +     +  L+QQ R
Sbjct  591  AKQSTWITQLVQQYR  605

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  384 bits (1442),  Expect = 1e-107, Method: Compositional matrix adjust.
 Identities = 247/615 (41%), Positives = 395/615 (65%), Gaps = 13/615 (2%)

Query  1    MRLIIAEKPSLGRAIAAVLPQPHSKGEGFVRAANGDVVSWCIGHLLEQAQPEAYNPQYKQ  60
            MRL++ EKPS G+ IA VL   +  +  +   + G VV+WCIGHL+E A PEAY  QYK+
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCY--NGAGTVVTWCIGHLIEAAPPEAYGEQYKR  58

Query  61   WRLDHLPIVPNEWQLEAKAQTRKQLSVLRKLVKEADSIVHAGDPDREGQLLVDEVIAFLK  120
            W L++LPI+P+ W++E+KA T  QL ++++LV +A  +V A D+DREG+++  E+I +  
Sbjct  59   WSLEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDL--  116

Query  121  VPATKRSSMQRLLVSDLNPQAVTRALQQLRPNKDFIPLSVSALARSRADWLYGINLTRAY  180
                 R+++QRL +S LN  ++ +AL  L+P+ + +PL  +ALARSRADWL G+NL+R +
Sbjct  117  --CGYRGPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLF  174

Query  181  TLKGQQGGLKAVLSVGRVQTPILGLIVRRDNEIADFISKPFYEVFAALHLNAEQPLSFYA  240
            TL G+Q+G  +VLSVGRVQTP L+L+V RD EIA F+S PF  +  +L   ++   SF A
Sbjct  175  TLLGRQAGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGH---SFLA  231

Query  241  KWLPSESCQAHQDDEGRVLNPKLAHNVAQRIRQQAAS-VTSIERKLKKQAAPLPYNLSSL  299
             W+++++C    DD GR L+   A++ A+R+R  +++ V ++     ++A+PLP++L++L
Sbjct  232  TWIAADGCS---DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTL  288

Query  300  QIDAAKAFGLSAQQVLDSCQSLYEKHQLITYPRSDCRYLPTEHYARRSVVLSAIANSANE  359
            Q   ++ ++L  Q+ LD  Q+LYE H+  TYPRSD  YLP    A  + VL+A+  +   
Sbjct  289  QDVCSRQLALDVQETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPS  348

Query  360  LASGVAQADTQYRSKAWDDKKVEAHHAIIPTEKSLDIQRLSRYEQKVYQLIARQYVMQFY  419
            L + + Q D   RS+AW+D KV AHH+IIPT  + ++  +S     VY+LI  +Y+ QF 
Sbjct  349  LRPLLEQLDRTQRSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFL  408

Query  420  PAFEYADTRIELDIAGGVFVATERETIKLGWKQLLPARKQSDQNADQDPSRPSLPKLEKG  479
            P +E+  T  +L  +G  + A  ++ I  GW Q+L++    + +++  P    LP L  G
Sbjct  409  PHYEFDRTTAQLLCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREG  468

Query  480  QVLWSGEPDVQEKNTQPPAYFTDATLLAAMTGIARFVTDSELKKILKETDGLGTEATRAG  539
                  + D++  +TQPP  +T++ L+ AM G+A++VTD+ LK+ LKET G+GTEATRA+
Sbjct  469  LSCQVNHVDLKALKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRAS  528

Query  540  IIELLFKRRFLQREGKSIRATDLGKALVAALPEACTLPDMTAQWEKQLNDITQKLLNYDQ  599
            II  L+ R +L + G+++RA+D +  L+ A+P A T P+ TA WE+ L+ I    +  + 
Sbjct  529  IIKGLLERGYLLKKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLET  588

Query  600  FMQPLALQLDALINQ  614
            F+   +  +  L++Q
Sbjct  589  FVAKQSTWITQLVQQ  603

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  382 bits (1438),  Expect = 2e-107, Method: Compositional matrix adjust.
 Identities = 254/619 (42%), Positives = 397/619 (65%), Gaps = 29/619 (4%)

Query  1    MRLFVAEKPSLARAIADVLPKPHSRGDGFIRC--GENDYVTWCVGHLLEQAEPDAYNPSY  58
            MRLF+ EKPS ++ IA VL   + RG G   C  G    VTWC+GHL+E A P+AY   Y
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQ-RGSG---CYNGAGTVVTWCIGHLIEAAPPEAYGEQY  56

Query  59   KQWRLEHLPIVPQKWQLIPRKEVAKQLKIVEKLIHQADELVNAGDPDREGQLLVDEVFSY  118
            K+W LE+LPI+P++W++ P+   A QLKIV +L+ QA ELV A D+DREG+++  E++  
Sbjct  57   KRWSLEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDL  116

Query  119  ADLPADKKDKIQRCLVSDLNPNAVEKAVNKLQPNRNFIPLATSALARARADWLYGINMTR  178
             +     ++ IQR  +S LN  ++ KA+  L+P+ + +PL ++ALAR+RADWL G+N++R
Sbjct  117  CGY----RGPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSR  172

Query  179  AYTIRGRQAGYNGVLSVGRVQTPVLGLIVRRDLEIENFRPKDFFEVLAQIKSEQNPTALS  238
             +T+ GRQAGY+GVLSVGRVQTP L+L+V RD EI  F +  F  +   + +  +    S
Sbjct  173  LFTLLGRQAGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGH----S  228

Query  239  FTALWQPSKACEDYQDEDGRVLSRALAENVIKRI-TRQPAEVTAYEDKREKQTAPLPYSL  297
            F A W ++ +C D   + GR L +A A++   R+    +A+V A    R ++++PLP+ L
Sbjct  229  FLATWIAADGCSD---DAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDL  285

Query  298  SALQIDAAKRFALSAQDVLDTCQSLYEKHKLITYPRSDCRYLPNEHFADRHAVMNAISVH  357
            ++LQ   ++++AL  Q+ LD  Q+LYE HK  TYPRSD  YLP+  +A+  AV+ A+   
Sbjct  286  GTLQDVCSRQLALDVQETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTT  345

Query  358  CTAYQTLPSAVNSEQKNRCWNDKKVEAHHAIIPT-AKNRAVSLTAREQDIYGLIARQYLM  416
              + + L   ++  Q++R WND KV AHH+IIPT       +++ +   +Y LI  +YL 
Sbjct  346  DPSLRPLLEQLDRTQRSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLA  405

Query  417  QFCPDAEYRKSKITLNIAGGTFIAQARNLQIAGWKE-LIGKEDDDEQLEAP-----LPVV  470
            QF P+ E+ ++   L  +G T+ A ++++ I+GW + L G E D+ + EA      LP +
Sbjct  406  QFLPHYEFDRTTAQLLCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPAL  465

Query  471  KKGQMLFCEKGEIVSK--KTQPPKPFTDATLLSAMTGIARFVQDKELKKILRETDGLGTE  528
            + G  L C+  ++  K  KTQPPKP+T++ L+ AM G+A++V D  LK+ L+ET G+GTE
Sbjct  466  REG--LSCQVNHVDLKALKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTE  523

Query  529  ATRAGIIELLFKRGFLYKKGRNIHSTEAGRILIQALPDLATQPDMTAQWEAQLNGISQKE  588
            ATRA+II  L+ RG+L KKGR +++++A+  LI+A+P   T+P+ TA WE  L+ I   +
Sbjct  524  ATRASIIKGLLERGYLLKKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGD  583

Query  589  TSYQSFMFQLTQMLPELVQ  607
             + ++F+ + +  + +LVQ
Sbjct  584  MTLETFVAKQSTWITQLVQ  602

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  382 bits (1438),  Expect = 2e-107, Method: Compositional matrix adjust.
 Identities = 251/619 (41%), Positives = 414/619 (67%), Gaps = 13/619 (2%)

Query  1    MILYIAEKPSLARAMAEVLPKPQQKGDGFIRLANGDVVSWCIGHLLEQAEPDAYDPAFKQ  60
            M L++ EKPS ++ +A VL   Q+ ++ +   + G VV+WCIGHL+E A P+AY+  +K+
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYN--GAGTVVTWCIGHLIEAAPPEAYGEQYKR  58

Query  61   WRREHLPIIPDDWKLVAKPNTkkqlavlkkllkEADSIVHAGDPDREGQLLVDEVISYCN  120
            W  E+LPIIP+ W++ +K+ T  QL ++K+L+ +A  +V A D+DREG+++  E+I  C 
Sbjct  59   WSLEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCG  118

Query  121  VPAAKREAVQRCLISDLNPAAVKKSLATLKPNKDFVPLSVSALARSRADWLYGINMTRLC  180
                 R ++QR  +S LN A+++K+L++LKP+ + +PL  +ALARSRADWL G+N++RL 
Sbjct  119  Y----RGPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLF  174

Query  181  TLAGRSTGYNGVLSVGRVQTPVLGLVVRRDRDIADFRPKPFYEVLALLQTDSKAQFRAKW  240
            TL GR +GY+GVLSVGRVQTP L+LVV RDR+IA F + PF  +   L T++ + F A W
Sbjct  175  TLLGRQAGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHS-FLATW  233

Query  241  QPSEACQPWQDEEGRVLSRALAENVIRRI-TGQPGRVLAADNKRQRIPPPLPYNLSALQI  299
             ++++C    D+ GR L +A A++   R+  + +++V+A    R R +PPLP++L++LQ 
Sbjct  234  IAADGCS---DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQD  290

Query  300  DAARRFGLSAKQVLDLCQGLYERHKLITYPRSDNRYLPAEHFGQGPAVLAAIAAVCPGLS  359
              +R+++L  ++ LD+ Q+LYE HK  TYPRSD+ YLP   +++ PAVLAA+ +  P+L 
Sbjct  291  VCSRQLALDVQETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLR  350

Query  360  QAVAAADTGIRGRAWNDARVEAHHAIIPTTRHTDGARLSGTERQIYELIARQYAAQFYPH  419
              +   D   R+RAWND++V AHH+IIPT   ++ A +S+    +Y LI  +Y AQF PH
Sbjct  351  PLLEQLDRTQRSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPH  410

Query  420  QELDEKKVELEIAGGRFVARARQQQVAGWKALFTQGKAdeeeddeLQAQ--LPALKTGDT  477
             E+D    +L  +G  + A ++Q  ++GW  +++   AD+ +++ +     LPAL+ G +
Sbjct  411  YEFDRTTAQLLCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLS  470

Query  478  VQCLQGELQEKQTQPPRPFTDATLLSAMTHIARFVTDGELKKILRDTDGLGTEATRAGII  537
             Q  + +L+  +TQPP+P+T++ L+ AM  +A++VTD  LK+ L++T G+GTEATRA+II
Sbjct  471  CQVNHVDLKALKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASII  530

Query  538  ELLFTRGFLERRGRQIHATETGSRLVDSLPASATTPDMTARWEAVLDAISRKQAGYRQFM  597
              L+ RG+L ++GR ++A+++++RL+D++PA+ T P+ TA WE  LD I   +     F+
Sbjct  531  KGLLERGYLLKKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFV  590

Query  598  EELQGQLPMLIDSVKPDAF  616
                  +  L++  ++ ++
Sbjct  591  AKQSTWITQLVQQYRAATL  609

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  382 bits (1436),  Expect = 3e-107, Method: Compositional matrix adjust.
 Identities = 249/607 (42%), Positives = 391/607 (65%), Gaps = 22/607 (3%)

Query  1    MRLFIAEKPSLGRAIADVLPKPHSRGDGFIRC--GNGDVVSWCIGHLLEQAEPEAYNPVF  58
            MRLF+ EKPS G+ IA VL   + RG G   C  G G VV+WCIGHL+E A PEAY   +
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQ-RGSG---CYNGAGTVVTWCIGHLIEAAPPEAYGEQY  56

Query  59   KQWRLEHLPIIPDQWQLKPKSKTRKQLTALRKLVKEATCIVHAGDPDREGQLLVDQVIDF  118
            K+W LE+LPIIP++W++ PK+ T  QL  +++LV +A+ +V A D+DREG+++  ++ID+
Sbjct  57   KRWSLEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDL  116

Query  119  LGVKGAKRESVQRCLINDLNPAAVKRSLDTLRSNKEFIPLATSALARSRADWLYGINMTR  178
             G +G+    +QR  ++ LN A+++++L++L+++ E +PL ++ALARSRADWL G+N++R
Sbjct  117  CGYRGP----IQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSR  172

Query  179  AYTLQGRKVGYEGLLSVGRVQTPILGMVVERDRAIEEFVSKPFYEVLAHLTTLTGEPTAF  238
             +TL GR+ GY+G+LSVGRVQTP L++VV RDR I  FVS PF  +   L+T      +F
Sbjct  173  LFTLLGRQAGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLST---GGHSF  229

Query  239  TAKWLPSEACEPYMDEDGRVLSKKLAQNVIAR--ITGENGVVEKVDKKAKAQAAPLPYNL  296
             A W+++++C    D+ GR L +  AQ+   R  ++G   VV     + + +A+PLP++L
Sbjct  230  LATWIAADGCS---DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVR-EAPPLPFDL  285

Query  297  SSLQIDAAKRFGFAAQKVLDICQNLYEKHKLITYPRSDSRYLPADHWHQANDVLQAISAN  356
            ++LQ   ++++++  Q  LDI Q LYE HK  TYPRSDS YLP     +   VL A+ + 
Sbjct  286  GTLQDVCSRQLALDVQETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTT  345

Query  357  VAELVQSVSGANSKLKSKAWNDAKVDAHHAIIPTAKKVSFSSITSEEQKVYSLIARQYVC  416
             + L   +   +   +S+AWND+KV AHH+IIPT    ++++I+     VY LI  +Y+ 
Sbjct  346  DPSLRPLLEQLDRTQRSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLA  405

Query  417  QFYPKWEYSDTVIHLKIAGGQFVSKARLTHKQGWKVLFERKGGEPNPKDDDEFP-SLTLP  475
            QF P  E+  T  +L  +G  + + ++     GW  ++   G E++  D++  P S  LP
Sbjct  406  QFLPHYEFDRTTAQLLCGGQTLQAVGKQVIIPGWHQVLA--GPEADNADGEAVPRSQVLP  463

Query  476  DLHVGQSVACRQGELLEKQTQPPKYFTDASLLAAMTGIARYVTDPDIKKILKDTDGLGTE  535
             L+ G S    + +L   +TQPPK +T++ L+ AM G+A+ VTDP +K+ LK+T G+GTE
Sbjct  464  ALREGLSCQVNHVDLKALKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTE  523

Query  536  ATRAGIIELLFKRNFLVRKGKQIHSTPAARGLVAALPSSATTPDMTAQWELVLNAISIRE  595
            ATRA+II  L+ R +L++KG+ ++++ AA  L+ A+P++ T P+ TA WE  L+ I   +
Sbjct  524  ATRASIIKGLLERGYLLKKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGD  583

Query  596  AQYTTFM  602
                TF+
Sbjct  584  MTLETFV  590

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  382 bits (1437),  Expect = 3e-107, Method: Compositional matrix adjust.
 Identities = 258/633 (41%), Positives = 417/633 (66%), Gaps = 25/633 (3%)

Query  2    MRLFIAEKPSLARAIADILPKPHRRGGGFIACGNDQMVTWCVGHLLEQAQPDAYDSRYAR  61
            MRLF+ EKPS ++ IA +L   +R +G +   G + +VTWC+GHL+E A P+AY+ +Y R
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYN--GAGTVVTWCIGHLIEAAPPEAYGEQYKR  58

Query  62   WSLADLPIIPEKWQLQPRPSVSKQLNVIKQLLQQADEVVHAGDPDREGQLLVDEVLDYLG  121
            WSL +LPIIPE+W+++P+++ + QL+++KQL+ QA E+V A D+DREG+++  E++D  G
Sbjct  59   WSLEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCG  118

Query  122  LAAEKRQNVRRCLINDLNPQAVERAVERLRYNREFIPLCVSALARARADWLYGINMTRAY  181
                 R  ++R  ++ LN  ++ +A+  L+ + E +PL  +ALAR+RADWL G+N++R +
Sbjct  119  Y----RGPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLF  174

Query  182  TILGRNAGYDGVLSVGRVQTPVLGLVVRRDEEIESFIPKDFFEVKAHIVTPADERFIALW  241
            T+LGR+AGYDGVLSVGRVQTP L+LVV RD EI  F++  F  +   + T +++ F+A W
Sbjct  175  TLLGRQAGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLST-GGHSFLATW  233

Query  242  QPSDSCESYQDEEGRLLHRPLAEHVVNRI-TGQPALVTSYNDKRESETAPLPFSLSTLQI  300
             ++D+C    D+ GR L+++ A++  +R+  + +A V +    R  E++PLPF L+TLQ 
Sbjct  234  IAADGCS---DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQD  290

Query  301  EAAKRFGLSAQQVLDICQRLYETHKLITYPRSDCRYLPEEHFAGRHSVLNAISLHQSDLL  360
              +++++L  Q+ LDI Q LYETHK  TYPRSD  YLPE  +A   +VL A+   ++ L 
Sbjct  291  VCSRQLALDVQETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLR  350

Query  361  P-LEVMDSDRRNRCWDDKKVDAHHAIIPTARASKVNLTTDEG-KVYRLVAQQYLMQFCPD  418
            P LE +D  +R+R W+D KV AHH+IIPT  ++++   +D +  VYRL+  +YL QF P+
Sbjct  351  PLLEQLDRTQRSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPH  410

Query  419  AQFRKCVIELDIAGGKFIAKARFLAEAGWRTLLGSKERDE-ENEGAP----LPVVAKGAE  473
             +F +   +L  +G  + A ++ +  +GW+ +L++ E D+ + E+ P    LP +  G  
Sbjct  411  YEFDRTTAQLLCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREG--  468

Query  474  LLCERGEVVER--QTQPPRPFTDASLLSAMTGIARFVQDKELKKVLRATDGLGTEATRAG  531
            L C+  +V  +  +TQPP+P+T++ L+ AM G+A++V D  LK+ L+ T G+GTEATRA+
Sbjct  469  LSCQVNHVDLKALKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRAS  528

Query  532  IIELLFKRTFLFKKGRYIHASPAGRALIHALPDIAARPDMTAHWESTLTQISEKNCRYQD  591
            II  L+ R +L+KKGR ++AS A+  LI+A+P   + P+ TA WE +L  I   +   + 
Sbjct  529  IIKGLLERGYLLKKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLET  588

Query  592  FMQPLVMTLQDLISQAKQNRSPQVFRGLPAGPS  624
            F+      + +L+   +Q R++ +   LP GP+
Sbjct  589  FVAKQSTWITQLV---QQYRAATLAIKLPEGPA  618

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  381 bits (1432),  Expect = 6e-107, Method: Compositional matrix adjust.
 Identities = 257/633 (41%), Positives = 417/633 (66%), Gaps = 25/633 (3%)

Query  1    MRLFIAEKPSLARAIADILPKPHRRGDGFIACGNDQMVTWCVGHLLEQAQPDAYDSRYAR  60
            MRLF+ EKPS ++ IA +L   +R ++ +   G + +VTWC+GHL+E A P+AY+ +Y R
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYN--GAGTVVTWCIGHLIEAAPPEAYGEQYKR  58

Query  61   WSLADLPIIPEKWQLQPRPSVSKQLNVIKQLLQQADEVVHAGDPDREGQLLVDEVLDYLG  120
            WSL +LPIIPE+W+++P+++ + QL+++KQL+ QA E+V A D+DREG+++  E++D  G
Sbjct  59   WSLEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCG  118

Query  121  LAAEKRQNVRRCLINDLNPQAVERAVERLRYNREFIPLCVSALARARADWLYGINMTRAY  180
                 R  ++R  ++ LN  ++ +A+  L+ + E +PL  +ALAR+RADWL G+N++R +
Sbjct  119  Y----RGPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLF  174

Query  181  TILGRNAGYDGVLSVGRVQTPVLGLVVRRDEEIESFIPKDFFEVKAHIVTPADERFIALW  240
            T+LGR+AGYDGVLSVGRVQTP L+LVV RD EI  F++  F  +   + T +++ F+A W
Sbjct  175  TLLGRQAGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLST-GGHSFLATW  233

Query  241  QPSDSCESYQDEEGRLLHRPLAEHVVNRI-TGQPALVTSYNDKRESETAPLPFSLSTLQI  299
             ++D+C    D+ GR L+++ A++  +R+  + +A V +    R  E++PLPF L+TLQ 
Sbjct  234  IAADGCS---DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQD  290

Query  300  EAAKRFGLSAQQVLDICQRLYETHKLITYPRSDCRYLPEEHFAGRHSVLNAISLHQSDLL  359
              +++++L  Q+ LDI Q LYETHK  TYPRSD  YLPE  +A   +VL A+   ++ L 
Sbjct  291  VCSRQLALDVQETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLR  350

Query  360  P-LEVMDSDRRNRCWDDKKVDAHHAIIPTARASKVNLTTDEG-KVYRLVAQQYLMQFCPD  417
            P LE +D  +R+R W+D KV AHH+IIPT  ++++   +D +  VYRL+  +YL QF P+
Sbjct  351  PLLEQLDRTQRSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPH  410

Query  418  AQFRKCVIELDIAGGKFIAKARFLAEAGWRTLLGSKERDE-ENEGAP----LPVVAKGAE  472
             +F +   +L  +G  + A ++ +  +GW+ +L++ E D+ + E+ P    LP +  G  
Sbjct  411  YEFDRTTAQLLCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREG--  468

Query  473  LLCERGEVVER--QTQPPRPFTDASLLSAMTGIARFVQDKELKKVLRATDGLGTEATRAG  530
            L C+  +V  +  +TQPP+P+T++ L+ AM G+A++V D  LK+ L+ T G+GTEATRA+
Sbjct  469  LSCQVNHVDLKALKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRAS  528

Query  531  IIELLFKRTFLFKKGRYIHASPAGRALIHALPDIAARPDMTAHWESTLTQISEKNCRYQD  590
            II  L+ R +L+KKGR ++AS A+  LI+A+P   + P+ TA WE +L  I   +   + 
Sbjct  529  IIKGLLERGYLLKKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLET  588

Query  591  FMQPLVMTLQDLISQAKQNRSPQVFRGLPAGPS  623
            F+      + +L+   +Q R++ +   LP GP+
Sbjct  589  FVAKQSTWITQLV---QQYRAATLAIKLPEGPA  618

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  381 bits (1433),  Expect = 6e-107, Method: Compositional matrix adjust.
 Identities = 257/633 (41%), Positives = 417/633 (66%), Gaps = 25/633 (3%)

Query  2    MRLFIAEKPSLARAIADILPKPHRRGDGFIACGNDQMVTWCVGHLLEQAQPDAYDSRYAR  61
            MRLF+ EKPS ++ IA +L   +R ++ +   G + +VTWC+GHL+E A P+AY+ +Y R
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYN--GAGTVVTWCIGHLIEAAPPEAYGEQYKR  58

Query  62   WSLADLPIIPEKWQLQPRPSVSKQLNVIKQLLQQADEVVHAGDPDREGQLLVDEVLDYLG  121
            WSL +LPIIPE+W+++P+++ + QL+++KQL+ QA E+V A D+DREG+++  E++D  G
Sbjct  59   WSLEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCG  118

Query  122  LAAEKRQNVRRCLINDLNPQAVERAVERLRYNREFIPLCVSALARARADWLYGINMTRAY  181
                 R  ++R  ++ LN  ++ +A+  L+ + E +PL  +ALAR+RADWL G+N++R +
Sbjct  119  Y----RGPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLF  174

Query  182  TILGRNAGYDGVLSVGRVQTPVLGLVVRRDEEIESFIPKDFFEVKAHIVTPADERFIALW  241
            T+LGR+AGYDGVLSVGRVQTP L+LVV RD EI  F++  F  +   + T +++ F+A W
Sbjct  175  TLLGRQAGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLST-GGHSFLATW  233

Query  242  QPSDSCESYQDEEGRLLHRPLAEHVVNRI-TGQPALVTSYNDKRESETAPLPFSLSTLQI  300
             ++D+C    D+ GR L+++ A++  +R+  + +A V +    R  E++PLPF L+TLQ 
Sbjct  234  IAADGCS---DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQD  290

Query  301  EAAKRFGLSAQQVLDICQRLYETHKLITYPRSDCRYLPEEHFAGRHSVLNAISLHQSDLL  360
              +++++L  Q+ LDI Q LYETHK  TYPRSD  YLPE  +A   +VL A+   ++ L 
Sbjct  291  VCSRQLALDVQETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLR  350

Query  361  P-LEVMDSDRRNRCWDDKKVDAHHAIIPTARASKVNLTTDEG-KVYRLVAQQYLMQFCPD  418
            P LE +D  +R+R W+D KV AHH+IIPT  ++++   +D +  VYRL+  +YL QF P+
Sbjct  351  PLLEQLDRTQRSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPH  410

Query  419  AQFRKCVIELDIAGGKFIAKARFLAEAGWRTLLGSKERDE-ENEGAP----LPVVAKGAE  473
             +F +   +L  +G  + A ++ +  +GW+ +L++ E D+ + E+ P    LP +  G  
Sbjct  411  YEFDRTTAQLLCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREG--  468

Query  474  LLCERGEVVER--QTQPPRPFTDASLLSAMTGIARFVQDKELKKVLRATDGLGTEATRAG  531
            L C+  +V  +  +TQPP+P+T++ L+ AM G+A++V D  LK+ L+ T G+GTEATRA+
Sbjct  469  LSCQVNHVDLKALKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRAS  528

Query  532  IIELLFKRTFLFKKGRYIHASPAGRALIHALPDIAARPDMTAHWESTLTQISEKNCRYQD  591
            II  L+ R +L+KKGR ++AS A+  LI+A+P   + P+ TA WE +L  I   +   + 
Sbjct  529  IIKGLLERGYLLKKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLET  588

Query  592  FMQPLVMTLQDLISQAKQNRSPQVFRGLPAGPS  624
            F+      + +L+   +Q R++ +   LP GP+
Sbjct  589  FVAKQSTWITQLV---QQYRAATLAIKLPEGPA  618

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  381 bits (1433),  Expect = 6e-107, Method: Compositional matrix adjust.
 Identities = 257/633 (41%), Positives = 417/633 (66%), Gaps = 25/633 (3%)

Query  2    MRLFIAEKPSLARAIADILPKPHRRGDGFIACGNDQMVTWCVGHLLEQAQPDAYDSRYAR  61
            MRLF+ EKPS ++ IA +L   +R ++ +   G + +VTWC+GHL+E A P+AY+ +Y R
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYN--GAGTVVTWCIGHLIEAAPPEAYGEQYKR  58

Query  62   WSLADLPIIPEKWQLQPRPSVSKQLNVIKQLLQQADEVVHAGDPDREGQLLVDEVLDYLG  121
            WSL +LPIIPE+W+++P+++ + QL+++KQL+ QA E+V A D+DREG+++  E++D  G
Sbjct  59   WSLEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCG  118

Query  122  LAAEKRQNVRRCLINDLNPQAVERAVERLRYNREFIPLCVSALARARADWLYGINMTRAY  181
                 R  ++R  ++ LN  ++ +A+  L+ + E +PL  +ALAR+RADWL G+N++R +
Sbjct  119  Y----RGPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLF  174

Query  182  TILGRNAGYDGVLSVGRVQTPVLGLVVRRDEEIESFIPKDFFEVKAHIVTPADERFIALW  241
            T+LGR+AGYDGVLSVGRVQTP L+LVV RD EI  F++  F  +   + T +++ F+A W
Sbjct  175  TLLGRQAGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLST-GGHSFLATW  233

Query  242  QPSDSCESYQDEEGRLLHRPLAEHVVNRI-TGQPALVTSYNDKRESETAPLPFSLSTLQI  300
             ++D+C    D+ GR L+++ A++  +R+  + +A V +    R  E++PLPF L+TLQ 
Sbjct  234  IAADGCS---DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQD  290

Query  301  EAAKRFGLSAQQVLDICQRLYETHKLITYPRSDCRYLPEEHFAGRHSVLNAISLHQSDLL  360
              +++++L  Q+ LDI Q LYETHK  TYPRSD  YLPE  +A   +VL A+   ++ L 
Sbjct  291  VCSRQLALDVQETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLR  350

Query  361  P-LEVMDSDRRNRCWDDKKVDAHHAIIPTARASKVNLTTDEG-KVYRLVAQQYLMQFCPD  418
            P LE +D  +R+R W+D KV AHH+IIPT  ++++   +D +  VYRL+  +YL QF P+
Sbjct  351  PLLEQLDRTQRSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPH  410

Query  419  AQFRKCVIELDIAGGKFIAKARFLAEAGWRTLLGSKERDE-ENEGAP----LPVVAKGAE  473
             +F +   +L  +G  + A ++ +  +GW+ +L++ E D+ + E+ P    LP +  G  
Sbjct  411  YEFDRTTAQLLCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREG--  468

Query  474  LLCERGEVVER--QTQPPRPFTDASLLSAMTGIARFVQDKELKKVLRATDGLGTEATRAG  531
            L C+  +V  +  +TQPP+P+T++ L+ AM G+A++V D  LK+ L+ T G+GTEATRA+
Sbjct  469  LSCQVNHVDLKALKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRAS  528

Query  532  IIELLFKRTFLFKKGRYIHASPAGRALIHALPDIAARPDMTAHWESTLTQISEKNCRYQD  591
            II  L+ R +L+KKGR ++AS A+  LI+A+P   + P+ TA WE +L  I   +   + 
Sbjct  529  IIKGLLERGYLLKKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLET  588

Query  592  FMQPLVMTLQDLISQAKQNRSPQVFRGLPAGPS  624
            F+      + +L+   +Q R++ +   LP GP+
Sbjct  589  FVAKQSTWITQLV---QQYRAATLAIKLPEGPA  618

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  381 bits (1431),  Expect = 8e-107, Method: Compositional matrix adjust.
 Identities = 247/615 (41%), Positives = 409/615 (67%), Gaps = 18/615 (2%)

Query  1    MRLFIAEKPSLARAIADVLPKPHRRGDGYIACGGDQVVTWCVGHLLEQAQPDSYNSRFAR  60
            MRLF+ EKPS ++ IA VL   +R ++ Y   G++ VVTWC+GHL+E A P++Y  ++ R
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYN--GAGTVVTWCIGHLIEAAPPEAYGEQYKR  58

Query  61   WSLADLPIVPEKWRLQPRPSVAKQLNVIKGLLEQASVVVHAGDPDREGQLLVDEVLDYLT  120
            WSL +LPI+PE+WR++P+++ A QL+++K L+ QAS +V A D+DREG+++  E++D   
Sbjct  59   WSLEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDL--  116

Query  121  LPAEKRAQVQRCLINDLNPQAVERAIGRLRENREFIPLCVSALARARADWLYGINMTRAY  180
                 R+ +QR  ++ LN  ++ +A+G L+ + E +PL  +ALAR+RADWL G+N++R +
Sbjct  117  --CGYRGPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLF  174

Query  181  TLLGRNAGYDGVLSVGRVQTPVLGLVVRRDEDIENFVAKDFFEVRAHIVTPADERFVALW  240
            TLLGR+AGYDGVLSVGRVQTP L+LVV RD +I  FV+  F  +   + T +++ F+A W
Sbjct  175  TLLGRQAGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLST-GGHSFLATW  233

Query  241  QPSDSCEPYQDEEGRLLHRPLAEHVVARIN-GQPAHVTSYNDKRENDTPPLPFSLSALQI  299
             ++D+C    D+ GR L+++ A++   R+  + +A+V +    R  ++PPLPF L++LQ 
Sbjct  234  IAADGCS---DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQD  290

Query  300  EAGKRFGLSAQTVLDTCQRLYETHKLITYPRSDSRYLPDEHFAGRHAVLNAINLHQPDLS  359
              +++++L  Q  LD  Q LYETHK  TYPRSDS YLP+  +A   AVL A+   +P L 
Sbjct  291  VCSRQLALDVQETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLR  350

Query  360  APTD-FNSDQKNRCWDDKKVDAHHAIIPTARSGQV-RLTDNEGQIYRLIATQYLMQFCPD  417
            +  + ++  Q++R W+D KV AHH+IIPT  ++++  ++D+   +YRLI ++YL QF P+
Sbjct  351  PLLEQLDRTQRSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPH  410

Query  418  AVYRKCVIELDIAGGKFLAKARFLAEAGWRALLGSKERDE-ENDGTPLPVVAKG--DALL  474
              + +   +L  +G  + A ++ +  +GW+ +L++ E D+ + ++ P + V  +  ++L 
Sbjct  411  YEFDRTTAQLLCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREGLS  470

Query  475  CERGEVLEK--QTQPPRPFTDATLLSAMTGIARFVQDKDLKKVLRATDGLGTEATRAGII  532
            C+  +V  K  +TQPP+P+T++ L+ AM G+A++V D  LK+ L+ T G+GTEATRA+II
Sbjct  471  CQVNHVDLKALKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRASII  530

Query  533  ELLFKRTFLFKKGRYIHSSPAGRALIHSLPEMAARPDMTAQWESTLTKISEKQCRYQDFM  592
              L+ R +L+KKGR +++S A+  LI+++P   + P+ TA WE +L  I   +   + F+
Sbjct  531  KGLLERGYLLKKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLETFV  590

Query  593  SPLVETLHSLIHQAR  607
            +     +  L++Q R
Sbjct  591  AKQSTWITQLVQQYR  605

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  380 bits (1429),  Expect = 1e-106, Method: Compositional matrix adjust.
 Identities = 249/619 (41%), Positives = 408/619 (66%), Gaps = 23/619 (3%)

Query  1    MRLFIAEKPSLARAIADVLPKPHRRGDGFIACGEQDMVTWCVGHLLEQAQPDVYDARYAR  60
            MRLF+ EKPS ++ IA VL   +R ++ +   G   +VTWC+GHL+E A P+ Y+ +Y R
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYN--GAGTVVTWCIGHLIEAAPPEAYGEQYKR  58

Query  61   WSLADLPIVPQKWLLQPRPSVSKQLNVIKKLLTQADEVIHAGDPDREGQLLVDEVLE---  117
            WSL +LPI+P++W ++P+++ + QL+++K+L+ QA E++ A D+DREG+++  E+++   
Sbjct  59   WSLEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCG  118

Query  118  YLALPEAKRQQVRRCLINDLNPQAVERAVSRLRENREFVPLCVSALARSRADWLYGINMT  177
            Y       R  ++R  ++ LN  ++ +A++ L+ + E +PL  +ALARSRADWL G+N++
Sbjct  119  Y-------RGPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLS  171

Query  178  RAYTLLGKNAGYEGVLSVGRVQTPVLGLVVRRDEEIDNFVSRDYFEVKAHIVTANERFIA  237
            R +TLLG++AGY+GVLSVGRVQTP L+LVV RD EI  FVS  +  +   + T+ + F+A
Sbjct  172  RLFTLLGRQAGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTGGHSFLA  231

Query  238  LWQPSDSCEPYQDEEGRLLHRPLAEHVVKRIE-GQPAQVTAYNDKRESETAPLPYSLSTL  296
             W ++D+C    D+ GR L+++ A++   R+  + +AQV A    R  E++PLP+ L+TL
Sbjct  232  TWIAADGCS---DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTL  288

Query  297  QIETAKRFGLSAQQVLDICQRLYETHKLITYPRSDCRYLPEEHFAGRHAVLNAIAAHQPD  356
            Q   +++++L  Q+ LDI Q LYETHK  TYPRSD  YLPE  +A   AVL A+ + +P 
Sbjct  289  QDVCSRQLALDVQETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPS  348

Query  357  LLPQPAA-DPERRNRCWDDSKVDAHHAIIPTARSAR-TSLTEQESQVYGLIARQYLMQFC  414
            L P     D  +R+R W+DSKV AHH+IIPT  +A  ++++++   VY LI  +YL QF 
Sbjct  349  LRPLLEQLDRTQRSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFL  408

Query  415  ADAVFRKCVIELDIAGGKFVAKARFLAEAGWRTLL-GHKERDEENEGMPLPVVAKG--DE  471
            ++  F +   +L  +G  + A ++ +  +GW+ +L G    + + E++P + V  +  + 
Sbjct  409  PHYEFDRTTAQLLCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREG  468

Query  472  LLCERGEVVER--QTQPPRPFTDATLLSAMTGIARFVQDKALKKILRETDGLGTEATRAG  529
            L C+  +V  +  +TQPP+P+T++ L+ AM G+A++V D  LK+ L+ET G+GTEATRA+
Sbjct  469  LSCQVNHVDLKALKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRAS  528

Query  530  IIELLFKRAFLIKKGRHIHATDAGKALIHALPPIAAHPDMTAHWEATLTQISEKRCRYQD  589
            II  L+ R++L+KKGR ++A+DA+  LI+A+P+  ++P+ TA WE +L  I       + 
Sbjct  529  IIKGLLERGYLLKKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLET  588

Query  590  FMQPLTQSLYELIQQARQS  608
            F+   +  + +L+QQ R +
Sbjct  589  FVAKQSTWITQLVQQYRAA  607

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  380 bits (1428),  Expect = 1e-106, Method: Compositional matrix adjust.
 Identities = 257/633 (41%), Positives = 417/633 (66%), Gaps = 25/633 (3%)

Query  1    MRLFIAEKPSLARAIADILPKPHRRGDGFIACGNDQMVTWCVGHLLEQAQPDAYDSRYAR  60
            MRLF+ EKPS ++ IA +L   +R ++ +   G + +VTWC+GHL+E A P+AY+ +Y R
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYN--GAGTVVTWCIGHLIEAAPPEAYGEQYKR  58

Query  61   WSLADLPIIPEKWQLQPRPSVSKQLNVIKQLLQQADEVVHAGDPDREGQLLVDEVLDYLG  120
            WSL +LPIIPE+W+++P+++ + QL+++KQL+ QA E+V A D+DREG+++  E++D  G
Sbjct  59   WSLEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCG  118

Query  121  LAAEKRQNVRRCLINDLNPQAVERAVERLRYNREFIPLCVSALARARADWLYGINMTRAY  180
                 R  ++R  ++ LN  ++ +A+  L+ + E +PL  +ALAR+RADWL G+N++R +
Sbjct  119  Y----RGPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLF  174

Query  181  TILGRNAGYDGVLSVGRVQTPVLGLVVRRDEEIESFIPKDFFEVKAHIVTPADERFIALW  240
            T+LGR+AGYDGVLSVGRVQTP L+LVV RD EI  F++  F  +   + T +++ F+A W
Sbjct  175  TLLGRQAGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLST-GGHSFLATW  233

Query  241  QPSDSCESYQDEEGRLLHRPLAEHVVNRI-TGQPALVTSYNDKRESETAPLPFSLSTLQI  299
             ++D+C    D+ GR L+++ A++  +R+  + +A V +    R  E++PLPF L+TLQ 
Sbjct  234  IAADGCS---DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQD  290

Query  300  EAAKRFGLSAQQVLDICQRLYETHKLITYPRSDCRYLPEEHFAGRHSVLNAISLHQSDLL  359
              +++++L  Q+ LDI Q LYETHK  TYPRSD  YLPE  +A   +VL A+   ++ L 
Sbjct  291  VCSRQLALDVQETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLR  350

Query  360  P-LEVMDSDRRNRCWDDKKVDAHHAIIPTARASKVNLTTDEG-KVYRLVAQQYLMQFCPD  417
            P LE +D  +R+R W+D KV AHH+IIPT  ++++   +D +  VYRL+  +YL QF P+
Sbjct  351  PLLEQLDRTQRSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPH  410

Query  418  AQFRKCVIELDIAGGKFIAKARFLAEAGWRTLLGSKERDE-ENEGAP----LPVVAKGAE  472
             +F +   +L  +G  + A ++ +  +GW+ +L++ E D+ + E+ P    LP +  G  
Sbjct  411  YEFDRTTAQLLCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREG--  468

Query  473  LLCERGEVVER--QTQPPRPFTDASLLSAMTGIARFVQDKELKKVLRATDGLGTEATRAG  530
            L C+  +V  +  +TQPP+P+T++ L+ AM G+A++V D  LK+ L+ T G+GTEATRA+
Sbjct  469  LSCQVNHVDLKALKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRAS  528

Query  531  IIELLFKRTFLFKKGRYIHASPAGRALIHALPDIAARPDMTAHWESTLTQISEKNCRYQD  590
            II  L+ R +L+KKGR ++AS A+  LI+A+P   + P+ TA WE +L  I   +   + 
Sbjct  529  IIKGLLERGYLLKKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLET  588

Query  591  FMQPLVMTLQDLISQAKQNRSPQVFRGLPVGPS  623
            F+      + +L+   +Q R++ +   LP GP+
Sbjct  589  FVAKQSTWITQLV---QQYRAATLAIKLPEGPA  618

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  380 bits (1428),  Expect = 1e-106, Method: Compositional matrix adjust.
 Identities = 257/633 (41%), Positives = 417/633 (66%), Gaps = 25/633 (3%)

Query  1    MRLFIAEKPSLARAIADILPKPHRRGDGFIACGNDQMVTWCVGHLLEQAQPDAYDSRYAR  60
            MRLF+ EKPS ++ IA +L   +R ++ +   G + +VTWC+GHL+E A P+AY+ +Y R
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYN--GAGTVVTWCIGHLIEAAPPEAYGEQYKR  58

Query  61   WSLADLPIIPEKWQLQPRPSVSKQLNVIKQLLQQADEVVHAGDPDREGQLLVDEVLDYLG  120
            WSL +LPIIPE+W+++P+++ + QL+++KQL+ QA E+V A D+DREG+++  E++D  G
Sbjct  59   WSLEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCG  118

Query  121  LAAEKRQNVRRCLINDLNPQAVERAVERLRYNREFIPLCVSALARARADWLYGINMTRAY  180
                 R  ++R  ++ LN  ++ +A+  L+ + E +PL  +ALAR+RADWL G+N++R +
Sbjct  119  Y----RGPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLF  174

Query  181  TILGRNAGYDGVLSVGRVQTPVLGLVVRRDEEIESFIPKDFFEVKAHIVTPADERFIALW  240
            T+LGR+AGYDGVLSVGRVQTP L+LVV RD EI  F++  F  +   + T +++ F+A W
Sbjct  175  TLLGRQAGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLST-GGHSFLATW  233

Query  241  QPSDSCESYQDEEGRLLHRPLAEHVVNRI-TGQPALVTSYNDKRESETAPLPFSLSTLQI  299
             ++D+C    D+ GR L+++ A++  +R+  + +A V +    R  E++PLPF L+TLQ 
Sbjct  234  IAADGCS---DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQD  290

Query  300  EAAKRFGLSAQQVLDICQRLYETHKLITYPRSDCRYLPEEHFAGRHSVLNAISLHQSDLL  359
              +++++L  Q+ LDI Q LYETHK  TYPRSD  YLPE  +A   +VL A+   ++ L 
Sbjct  291  VCSRQLALDVQETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLR  350

Query  360  P-LEVMDSDRRNRCWDDKKVDAHHAIIPTARASKVNLTTDEG-KVYRLVAQQYLMQFCPD  417
            P LE +D  +R+R W+D KV AHH+IIPT  ++++   +D +  VYRL+  +YL QF P+
Sbjct  351  PLLEQLDRTQRSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPH  410

Query  418  AQFRKCVIELDIAGGKFIAKARFLAEAGWRTLLGSKERDE-ENEGAP----LPVVAKGAE  472
             +F +   +L  +G  + A ++ +  +GW+ +L++ E D+ + E+ P    LP +  G  
Sbjct  411  YEFDRTTAQLLCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREG--  468

Query  473  LLCERGEVVER--QTQPPRPFTDASLLSAMTGIARFVQDKELKKVLRATDGLGTEATRAG  530
            L C+  +V  +  +TQPP+P+T++ L+ AM G+A++V D  LK+ L+ T G+GTEATRA+
Sbjct  469  LSCQVNHVDLKALKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRAS  528

Query  531  IIELLFKRTFLFKKGRYIHASPAGRALIHALPDIAARPDMTAHWESTLTQISEKNCRYQD  590
            II  L+ R +L+KKGR ++AS A+  LI+A+P   + P+ TA WE +L  I   +   + 
Sbjct  529  IIKGLLERGYLLKKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLET  588

Query  591  FMQPLVMTLQDLISQAKQNRSPQVFRGLPVGPS  623
            F+      + +L+   +Q R++ +   LP GP+
Sbjct  589  FVAKQSTWITQLV---QQYRAATLAIKLPEGPA  618

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  380 bits (1429),  Expect = 1e-106, Method: Compositional matrix adjust.
 Identities = 257/633 (41%), Positives = 417/633 (66%), Gaps = 25/633 (3%)

Query  2    MRLFIAEKPSLARAIADILPKPHRRGDGFIACGNDQMVTWCVGHLLEQAQPDAYDSRYAR  61
            MRLF+ EKPS ++ IA +L   +R ++ +   G + +VTWC+GHL+E A P+AY+ +Y R
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYN--GAGTVVTWCIGHLIEAAPPEAYGEQYKR  58

Query  62   WSLADLPIIPEKWQLQPRPSVSKQLNVIKQLLQQADEVVHAGDPDREGQLLVDEVLDYLG  121
            WSL +LPIIPE+W+++P+++ + QL+++KQL+ QA E+V A D+DREG+++  E++D  G
Sbjct  59   WSLEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCG  118

Query  122  LAAEKRQNVRRCLINDLNPQAVERAVERLRYNREFIPLCVSALARARADWLYGINMTRAY  181
                 R  ++R  ++ LN  ++ +A+  L+ + E +PL  +ALAR+RADWL G+N++R +
Sbjct  119  Y----RGPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLF  174

Query  182  TILGRNAGYDGVLSVGRVQTPVLGLVVRRDEEIESFIPKDFFEVKAHIVTPADERFIALW  241
            T+LGR+AGYDGVLSVGRVQTP L+LVV RD EI  F++  F  +   + T +++ F+A W
Sbjct  175  TLLGRQAGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLST-GGHSFLATW  233

Query  242  QPSDSCESYQDEEGRLLHRPLAEHVVNRI-TGQPALVTSYNDKRESETAPLPFSLSTLQI  300
             ++D+C    D+ GR L+++ A++  +R+  + +A V +    R  E++PLPF L+TLQ 
Sbjct  234  IAADGCS---DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQD  290

Query  301  EAAKRFGLSAQQVLDICQRLYETHKLITYPRSDCRYLPEEHFAGRHSVLNAISLHQSDLL  360
              +++++L  Q+ LDI Q LYETHK  TYPRSD  YLPE  +A   +VL A+   ++ L 
Sbjct  291  VCSRQLALDVQETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLR  350

Query  361  P-LEVMDSDRRNRCWDDKKVDAHHAIIPTARASKVNLTTDEG-KVYRLVAQQYLMQFCPD  418
            P LE +D  +R+R W+D KV AHH+IIPT  ++++   +D +  VYRL+  +YL QF P+
Sbjct  351  PLLEQLDRTQRSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPH  410

Query  419  AQFRKCVIELDIAGGKFIAKARFLAEAGWRTLLGSKERDE-ENEGAP----LPVVAKGAE  473
             +F +   +L  +G  + A ++ +  +GW+ +L++ E D+ + E+ P    LP +  G  
Sbjct  411  YEFDRTTAQLLCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREG--  468

Query  474  LLCERGEVVER--QTQPPRPFTDASLLSAMTGIARFVQDKELKKVLRATDGLGTEATRAG  531
            L C+  +V  +  +TQPP+P+T++ L+ AM G+A++V D  LK+ L+ T G+GTEATRA+
Sbjct  469  LSCQVNHVDLKALKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRAS  528

Query  532  IIELLFKRTFLFKKGRYIHASPAGRALIHALPDIAARPDMTAHWESTLTQISEKNCRYQD  591
            II  L+ R +L+KKGR ++AS A+  LI+A+P   + P+ TA WE +L  I   +   + 
Sbjct  529  IIKGLLERGYLLKKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLET  588

Query  592  FMQPLVMTLQDLISQAKQNRSPQVFRGLPVGPS  624
            F+      + +L+   +Q R++ +   LP GP+
Sbjct  589  FVAKQSTWITQLV---QQYRAATLAIKLPEGPA  618

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  380 bits (1428),  Expect = 1e-106, Method: Compositional matrix adjust.
 Identities = 257/633 (41%), Positives = 417/633 (66%), Gaps = 25/633 (3%)

Query  1    MRLFIAEKPSLARAIADILPKPHRRGDGFIACGNDQMVTWCVGHLLEQAQPDAYDSRYAR  60
            MRLF+ EKPS ++ IA +L   +R ++ +   G + +VTWC+GHL+E A P+AY+ +Y R
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYN--GAGTVVTWCIGHLIEAAPPEAYGEQYKR  58

Query  61   WSLADLPIIPEKWQLQPRPSVSKQLNVIKQLLQQADEVVHAGDPDREGQLLVDEVLDYLG  120
            WSL +LPIIPE+W+++P+++ + QL+++KQL+ QA E+V A D+DREG+++  E++D  G
Sbjct  59   WSLEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCG  118

Query  121  LAAEKRQNVRRCLINDLNPQAVERAVERLRYNREFIPLCVSALARARADWLYGINMTRAY  180
                 R  ++R  ++ LN  ++ +A+  L+ + E +PL  +ALAR+RADWL G+N++R +
Sbjct  119  Y----RGPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLF  174

Query  181  TILGRNAGYDGVLSVGRVQTPVLGLVVRRDEEIESFIPKDFFEVKAHIVTPADERFIALW  240
            T+LGR+AGYDGVLSVGRVQTP L+LVV RD EI  F++  F  +   + T +++ F+A W
Sbjct  175  TLLGRQAGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLST-GGHSFLATW  233

Query  241  QPSDSCESYQDEEGRLLHRPLAEHVVNRI-TGQPALVTSYNDKRESETAPLPFSLSTLQI  299
             ++D+C    D+ GR L+++ A++  +R+  + +A V +    R  E++PLPF L+TLQ 
Sbjct  234  IAADGCS---DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQD  290

Query  300  EAAKRFGLSAQQVLDICQRLYETHKLITYPRSDCRYLPEEHFAGRHSVLNAISLHQSDLL  359
              +++++L  Q+ LDI Q LYETHK  TYPRSD  YLPE  +A   +VL A+   ++ L 
Sbjct  291  VCSRQLALDVQETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLR  350

Query  360  P-LEVMDSDRRNRCWDDKKVDAHHAIIPTARASKVNLTTDEG-KVYRLVAQQYLMQFCPD  417
            P LE +D  +R+R W+D KV AHH+IIPT  ++++   +D +  VYRL+  +YL QF P+
Sbjct  351  PLLEQLDRTQRSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPH  410

Query  418  AQFRKCVIELDIAGGKFIAKARFLAEAGWRTLLGSKERDE-ENEGAP----LPVVAKGAE  472
             +F +   +L  +G  + A ++ +  +GW+ +L++ E D+ + E+ P    LP +  G  
Sbjct  411  YEFDRTTAQLLCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREG--  468

Query  473  LLCERGEVVER--QTQPPRPFTDASLLSAMTGIARFVQDKELKKVLRATDGLGTEATRAG  530
            L C+  +V  +  +TQPP+P+T++ L+ AM G+A++V D  LK+ L+ T G+GTEATRA+
Sbjct  469  LSCQVNHVDLKALKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRAS  528

Query  531  IIELLFKRTFLFKKGRYIHASPAGRALIHALPDIAARPDMTAHWESTLTQISEKNCRYQD  590
            II  L+ R +L+KKGR ++AS A+  LI+A+P   + P+ TA WE +L  I   +   + 
Sbjct  529  IIKGLLERGYLLKKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLET  588

Query  591  FMQPLVMTLQDLISQAKQNRSPQVFRGLPVGPS  623
            F+      + +L+   +Q R++ +   LP GP+
Sbjct  589  FVAKQSTWITQLV---QQYRAATLAIKLPEGPA  618

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  380 bits (1429),  Expect = 1e-106, Method: Compositional matrix adjust.
 Identities = 257/633 (41%), Positives = 417/633 (66%), Gaps = 25/633 (3%)

Query  2    MRLFIAEKPSLARAIADILPKPHRRGDGFIACGNDQMVTWCVGHLLEQAQPDAYDSRYAR  61
            MRLF+ EKPS ++ IA +L   +R ++ +   G + +VTWC+GHL+E A P+AY+ +Y R
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYN--GAGTVVTWCIGHLIEAAPPEAYGEQYKR  58

Query  62   WSLADLPIIPEKWQLQPRPSVSKQLNVIKQLLQQADEVVHAGDPDREGQLLVDEVLDYLG  121
            WSL +LPIIPE+W+++P+++ + QL+++KQL+ QA E+V A D+DREG+++  E++D  G
Sbjct  59   WSLEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCG  118

Query  122  LAAEKRQNVRRCLINDLNPQAVERAVERLRYNREFIPLCVSALARARADWLYGINMTRAY  181
                 R  ++R  ++ LN  ++ +A+  L+ + E +PL  +ALAR+RADWL G+N++R +
Sbjct  119  Y----RGPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLF  174

Query  182  TILGRNAGYDGVLSVGRVQTPVLGLVVRRDEEIESFIPKDFFEVKAHIVTPADERFIALW  241
            T+LGR+AGYDGVLSVGRVQTP L+LVV RD EI  F++  F  +   + T +++ F+A W
Sbjct  175  TLLGRQAGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLST-GGHSFLATW  233

Query  242  QPSDSCESYQDEEGRLLHRPLAEHVVNRI-TGQPALVTSYNDKRESETAPLPFSLSTLQI  300
             ++D+C    D+ GR L+++ A++  +R+  + +A V +    R  E++PLPF L+TLQ 
Sbjct  234  IAADGCS---DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQD  290

Query  301  EAAKRFGLSAQQVLDICQRLYETHKLITYPRSDCRYLPEEHFAGRHSVLNAISLHQSDLL  360
              +++++L  Q+ LDI Q LYETHK  TYPRSD  YLPE  +A   +VL A+   ++ L 
Sbjct  291  VCSRQLALDVQETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLR  350

Query  361  P-LEVMDSDRRNRCWDDKKVDAHHAIIPTARASKVNLTTDEG-KVYRLVAQQYLMQFCPD  418
            P LE +D  +R+R W+D KV AHH+IIPT  ++++   +D +  VYRL+  +YL QF P+
Sbjct  351  PLLEQLDRTQRSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPH  410

Query  419  AQFRKCVIELDIAGGKFIAKARFLAEAGWRTLLGSKERDE-ENEGAP----LPVVAKGAE  473
             +F +   +L  +G  + A ++ +  +GW+ +L++ E D+ + E+ P    LP +  G  
Sbjct  411  YEFDRTTAQLLCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREG--  468

Query  474  LLCERGEVVER--QTQPPRPFTDASLLSAMTGIARFVQDKELKKVLRATDGLGTEATRAG  531
            L C+  +V  +  +TQPP+P+T++ L+ AM G+A++V D  LK+ L+ T G+GTEATRA+
Sbjct  469  LSCQVNHVDLKALKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRAS  528

Query  532  IIELLFKRTFLFKKGRYIHASPAGRALIHALPDIAARPDMTAHWESTLTQISEKNCRYQD  591
            II  L+ R +L+KKGR ++AS A+  LI+A+P   + P+ TA WE +L  I   +   + 
Sbjct  529  IIKGLLERGYLLKKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLET  588

Query  592  FMQPLVMTLQDLISQAKQNRSPQVFRGLPVGPS  624
            F+      + +L+   +Q R++ +   LP GP+
Sbjct  589  FVAKQSTWITQLV---QQYRAATLAIKLPEGPA  618

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  380 bits (1428),  Expect = 1e-106, Method: Compositional matrix adjust.
 Identities = 257/633 (41%), Positives = 417/633 (66%), Gaps = 25/633 (3%)

Query  1    MRLFIAEKPSLARAIADILPKPHRRGDGFIACGNDQMVTWCVGHLLEQAQPDAYDSRYAR  60
            MRLF+ EKPS ++ IA +L   +R ++ +   G + +VTWC+GHL+E A P+AY+ +Y R
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYN--GAGTVVTWCIGHLIEAAPPEAYGEQYKR  58

Query  61   WSLADLPIIPEKWQLQPRPSVSKQLNVIKQLLQQADEVVHAGDPDREGQLLVDEVLDYLG  120
            WSL +LPIIPE+W+++P+++ + QL+++KQL+ QA E+V A D+DREG+++  E++D  G
Sbjct  59   WSLEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCG  118

Query  121  LAAEKRQNVRRCLINDLNPQAVERAVERLRYNREFIPLCVSALARARADWLYGINMTRAY  180
                 R  ++R  ++ LN  ++ +A+  L+ + E +PL  +ALAR+RADWL G+N++R +
Sbjct  119  Y----RGPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLF  174

Query  181  TILGRNAGYDGVLSVGRVQTPVLGLVVRRDEEIESFIPKDFFEVKAHIVTPADERFIALW  240
            T+LGR+AGYDGVLSVGRVQTP L+LVV RD EI  F++  F  +   + T +++ F+A W
Sbjct  175  TLLGRQAGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLST-GGHSFLATW  233

Query  241  QPSDSCESYQDEEGRLLHRPLAEHVVNRI-TGQPALVTSYNDKRESETAPLPFSLSTLQI  299
             ++D+C    D+ GR L+++ A++  +R+  + +A V +    R  E++PLPF L+TLQ 
Sbjct  234  IAADGCS---DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQD  290

Query  300  EAAKRFGLSAQQVLDICQRLYETHKLITYPRSDCRYLPEEHFAGRHSVLNAISLHQSDLL  359
              +++++L  Q+ LDI Q LYETHK  TYPRSD  YLPE  +A   +VL A+   ++ L 
Sbjct  291  VCSRQLALDVQETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLR  350

Query  360  P-LEVMDSDRRNRCWDDKKVDAHHAIIPTARASKVNLTTDEG-KVYRLVAQQYLMQFCPD  417
            P LE +D  +R+R W+D KV AHH+IIPT  ++++   +D +  VYRL+  +YL QF P+
Sbjct  351  PLLEQLDRTQRSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPH  410

Query  418  AQFRKCVIELDIAGGKFIAKARFLAEAGWRTLLGSKERDE-ENEGAP----LPVVAKGAE  472
             +F +   +L  +G  + A ++ +  +GW+ +L++ E D+ + E+ P    LP +  G  
Sbjct  411  YEFDRTTAQLLCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREG--  468

Query  473  LLCERGEVVER--QTQPPRPFTDASLLSAMTGIARFVQDKELKKVLRATDGLGTEATRAG  530
            L C+  +V  +  +TQPP+P+T++ L+ AM G+A++V D  LK+ L+ T G+GTEATRA+
Sbjct  469  LSCQVNHVDLKALKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRAS  528

Query  531  IIELLFKRTFLFKKGRYIHASPAGRALIHALPDIAARPDMTAHWESTLTQISEKNCRYQD  590
            II  L+ R +L+KKGR ++AS A+  LI+A+P   + P+ TA WE +L  I   +   + 
Sbjct  529  IIKGLLERGYLLKKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLET  588

Query  591  FMQPLVMTLQDLISQAKQNRSPQVFRGLPVGPS  623
            F+      + +L+   +Q R++ +   LP GP+
Sbjct  589  FVAKQSTWITQLV---QQYRAATLAIKLPEGPA  618

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  380 bits (1428),  Expect = 1e-106, Method: Compositional matrix adjust.
 Identities = 257/633 (41%), Positives = 417/633 (66%), Gaps = 25/633 (3%)

Query  1    MRLFIAEKPSLARAIADILPKPHRRGDGFIACGNDQMVTWCVGHLLEQAQPDAYDSRYAR  60
            MRLF+ EKPS ++ IA +L   +R ++ +   G + +VTWC+GHL+E A P+AY+ +Y R
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYN--GAGTVVTWCIGHLIEAAPPEAYGEQYKR  58

Query  61   WSLADLPIIPEKWQLQPRPSVSKQLNVIKQLLQQADEVVHAGDPDREGQLLVDEVLDYLG  120
            WSL +LPIIPE+W+++P+++ + QL+++KQL+ QA E+V A D+DREG+++  E++D  G
Sbjct  59   WSLEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCG  118

Query  121  LAAEKRQNVRRCLINDLNPQAVERAVERLRYNREFIPLCVSALARARADWLYGINMTRAY  180
                 R  ++R  ++ LN  ++ +A+  L+ + E +PL  +ALAR+RADWL G+N++R +
Sbjct  119  Y----RGPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLF  174

Query  181  TILGRNAGYDGVLSVGRVQTPVLGLVVRRDEEIESFIPKDFFEVKAHIVTPADERFIALW  240
            T+LGR+AGYDGVLSVGRVQTP L+LVV RD EI  F++  F  +   + T +++ F+A W
Sbjct  175  TLLGRQAGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLST-GGHSFLATW  233

Query  241  QPSDSCESYQDEEGRLLHRPLAEHVVNRI-TGQPALVTSYNDKRESETAPLPFSLSTLQI  299
             ++D+C    D+ GR L+++ A++  +R+  + +A V +    R  E++PLPF L+TLQ 
Sbjct  234  IAADGCS---DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQD  290

Query  300  EAAKRFGLSAQQVLDICQRLYETHKLITYPRSDCRYLPEEHFAGRHSVLNAISLHQSDLL  359
              +++++L  Q+ LDI Q LYETHK  TYPRSD  YLPE  +A   +VL A+   ++ L 
Sbjct  291  VCSRQLALDVQETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLR  350

Query  360  P-LEVMDSDRRNRCWDDKKVDAHHAIIPTARASKVNLTTDEG-KVYRLVAQQYLMQFCPD  417
            P LE +D  +R+R W+D KV AHH+IIPT  ++++   +D +  VYRL+  +YL QF P+
Sbjct  351  PLLEQLDRTQRSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPH  410

Query  418  AQFRKCVIELDIAGGKFIAKARFLAEAGWRTLLGSKERDE-ENEGAP----LPVVAKGAE  472
             +F +   +L  +G  + A ++ +  +GW+ +L++ E D+ + E+ P    LP +  G  
Sbjct  411  YEFDRTTAQLLCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREG--  468

Query  473  LLCERGEVVER--QTQPPRPFTDASLLSAMTGIARFVQDKELKKVLRATDGLGTEATRAG  530
            L C+  +V  +  +TQPP+P+T++ L+ AM G+A++V D  LK+ L+ T G+GTEATRA+
Sbjct  469  LSCQVNHVDLKALKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRAS  528

Query  531  IIELLFKRTFLFKKGRYIHASPAGRALIHALPDIAARPDMTAHWESTLTQISEKNCRYQD  590
            II  L+ R +L+KKGR ++AS A+  LI+A+P   + P+ TA WE +L  I   +   + 
Sbjct  529  IIKGLLERGYLLKKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLET  588

Query  591  FMQPLVMTLQDLISQAKQNRSPQVFRGLPVGPS  623
            F+      + +L+   +Q R++ +   LP GP+
Sbjct  589  FVAKQSTWITQLV---QQYRAATLAIKLPEGPA  618

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  380 bits (1428),  Expect = 1e-106, Method: Compositional matrix adjust.
 Identities = 257/633 (41%), Positives = 417/633 (66%), Gaps = 25/633 (3%)

Query  1    MRLFIAEKPSLARAIADILPKPHRRGDGFIACGNDQMVTWCVGHLLEQAQPDAYDSRYAR  60
            MRLF+ EKPS ++ IA +L   +R ++ +   G + +VTWC+GHL+E A P+AY+ +Y R
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYN--GAGTVVTWCIGHLIEAAPPEAYGEQYKR  58

Query  61   WSLADLPIIPEKWQLQPRPSVSKQLNVIKQLLQQADEVVHAGDPDREGQLLVDEVLDYLG  120
            WSL +LPIIPE+W+++P+++ + QL+++KQL+ QA E+V A D+DREG+++  E++D  G
Sbjct  59   WSLEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCG  118

Query  121  LAAEKRQNVRRCLINDLNPQAVERAVERLRYNREFIPLCVSALARARADWLYGINMTRAY  180
                 R  ++R  ++ LN  ++ +A+  L+ + E +PL  +ALAR+RADWL G+N++R +
Sbjct  119  Y----RGPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLF  174

Query  181  TILGRNAGYDGVLSVGRVQTPVLGLVVRRDEEIESFIPKDFFEVKAHIVTPADERFIALW  240
            T+LGR+AGYDGVLSVGRVQTP L+LVV RD EI  F++  F  +   + T +++ F+A W
Sbjct  175  TLLGRQAGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLST-GGHSFLATW  233

Query  241  QPSDSCESYQDEEGRLLHRPLAEHVVNRI-TGQPALVTSYNDKRESETAPLPFSLSTLQI  299
             ++D+C    D+ GR L+++ A++  +R+  + +A V +    R  E++PLPF L+TLQ 
Sbjct  234  IAADGCS---DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQD  290

Query  300  EAAKRFGLSAQQVLDICQRLYETHKLITYPRSDCRYLPEEHFAGRHSVLNAISLHQSDLL  359
              +++++L  Q+ LDI Q LYETHK  TYPRSD  YLPE  +A   +VL A+   ++ L 
Sbjct  291  VCSRQLALDVQETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLR  350

Query  360  P-LEVMDSDRRNRCWDDKKVDAHHAIIPTARASKVNLTTDEG-KVYRLVAQQYLMQFCPD  417
            P LE +D  +R+R W+D KV AHH+IIPT  ++++   +D +  VYRL+  +YL QF P+
Sbjct  351  PLLEQLDRTQRSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPH  410

Query  418  AQFRKCVIELDIAGGKFIAKARFLAEAGWRTLLGSKERDE-ENEGAP----LPVVAKGAE  472
             +F +   +L  +G  + A ++ +  +GW+ +L++ E D+ + E+ P    LP +  G  
Sbjct  411  YEFDRTTAQLLCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREG--  468

Query  473  LLCERGEVVER--QTQPPRPFTDASLLSAMTGIARFVQDKELKKVLRATDGLGTEATRAG  530
            L C+  +V  +  +TQPP+P+T++ L+ AM G+A++V D  LK+ L+ T G+GTEATRA+
Sbjct  469  LSCQVNHVDLKALKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRAS  528

Query  531  IIELLFKRTFLFKKGRYIHASPAGRALIHALPDIAARPDMTAHWESTLTQISEKNCRYQD  590
            II  L+ R +L+KKGR ++AS A+  LI+A+P   + P+ TA WE +L  I   +   + 
Sbjct  529  IIKGLLERGYLLKKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLET  588

Query  591  FMQPLVMTLQDLISQAKQNRSPQVFRGLPVGPS  623
            F+      + +L+   +Q R++ +   LP GP+
Sbjct  589  FVAKQSTWITQLV---QQYRAATLAIKLPEGPA  618

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  380 bits (1429),  Expect = 1e-106, Method: Compositional matrix adjust.
 Identities = 257/633 (41%), Positives = 417/633 (66%), Gaps = 25/633 (3%)

Query  2    MRLFIAEKPSLARAIADILPKPHRRGDGFIACGNDQMVTWCVGHLLEQAQPDAYDSRYAR  61
            MRLF+ EKPS ++ IA +L   +R ++ +   G + +VTWC+GHL+E A P+AY+ +Y R
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYN--GAGTVVTWCIGHLIEAAPPEAYGEQYKR  58

Query  62   WSLADLPIIPEKWQLQPRPSVSKQLNVIKQLLQQADEVVHAGDPDREGQLLVDEVLDYLG  121
            WSL +LPIIPE+W+++P+++ + QL+++KQL+ QA E+V A D+DREG+++  E++D  G
Sbjct  59   WSLEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCG  118

Query  122  LAAEKRQNVRRCLINDLNPQAVERAVERLRYNREFIPLCVSALARARADWLYGINMTRAY  181
                 R  ++R  ++ LN  ++ +A+  L+ + E +PL  +ALAR+RADWL G+N++R +
Sbjct  119  Y----RGPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLF  174

Query  182  TILGRNAGYDGVLSVGRVQTPVLGLVVRRDEEIESFIPKDFFEVKAHIVTPADERFIALW  241
            T+LGR+AGYDGVLSVGRVQTP L+LVV RD EI  F++  F  +   + T +++ F+A W
Sbjct  175  TLLGRQAGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLST-GGHSFLATW  233

Query  242  QPSDSCESYQDEEGRLLHRPLAEHVVNRI-TGQPALVTSYNDKRESETAPLPFSLSTLQI  300
             ++D+C    D+ GR L+++ A++  +R+  + +A V +    R  E++PLPF L+TLQ 
Sbjct  234  IAADGCS---DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQD  290

Query  301  EAAKRFGLSAQQVLDICQRLYETHKLITYPRSDCRYLPEEHFAGRHSVLNAISLHQSDLL  360
              +++++L  Q+ LDI Q LYETHK  TYPRSD  YLPE  +A   +VL A+   ++ L 
Sbjct  291  VCSRQLALDVQETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLR  350

Query  361  P-LEVMDSDRRNRCWDDKKVDAHHAIIPTARASKVNLTTDEG-KVYRLVAQQYLMQFCPD  418
            P LE +D  +R+R W+D KV AHH+IIPT  ++++   +D +  VYRL+  +YL QF P+
Sbjct  351  PLLEQLDRTQRSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPH  410

Query  419  AQFRKCVIELDIAGGKFIAKARFLAEAGWRTLLGSKERDE-ENEGAP----LPVVAKGAE  473
             +F +   +L  +G  + A ++ +  +GW+ +L++ E D+ + E+ P    LP +  G  
Sbjct  411  YEFDRTTAQLLCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREG--  468

Query  474  LLCERGEVVER--QTQPPRPFTDASLLSAMTGIARFVQDKELKKVLRATDGLGTEATRAG  531
            L C+  +V  +  +TQPP+P+T++ L+ AM G+A++V D  LK+ L+ T G+GTEATRA+
Sbjct  469  LSCQVNHVDLKALKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRAS  528

Query  532  IIELLFKRTFLFKKGRYIHASPAGRALIHALPDIAARPDMTAHWESTLTQISEKNCRYQD  591
            II  L+ R +L+KKGR ++AS A+  LI+A+P   + P+ TA WE +L  I   +   + 
Sbjct  529  IIKGLLERGYLLKKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLET  588

Query  592  FMQPLVMTLQDLISQAKQNRSPQVFRGLPVGPS  624
            F+      + +L+   +Q R++ +   LP GP+
Sbjct  589  FVAKQSTWITQLV---QQYRAATLAIKLPEGPA  618

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  380 bits (1429),  Expect = 1e-106, Method: Compositional matrix adjust.
 Identities = 257/633 (41%), Positives = 417/633 (66%), Gaps = 25/633 (3%)

Query  2    MRLFIAEKPSLARAIADILPKPHRRGDGFIACGNDQMVTWCVGHLLEQAQPDAYDSRYAR  61
            MRLF+ EKPS ++ IA +L   +R ++ +   G + +VTWC+GHL+E A P+AY+ +Y R
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYN--GAGTVVTWCIGHLIEAAPPEAYGEQYKR  58

Query  62   WSLADLPIIPEKWQLQPRPSVSKQLNVIKQLLQQADEVVHAGDPDREGQLLVDEVLDYLG  121
            WSL +LPIIPE+W+++P+++ + QL+++KQL+ QA E+V A D+DREG+++  E++D  G
Sbjct  59   WSLEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCG  118

Query  122  LAAEKRQNVRRCLINDLNPQAVERAVERLRYNREFIPLCVSALARARADWLYGINMTRAY  181
                 R  ++R  ++ LN  ++ +A+  L+ + E +PL  +ALAR+RADWL G+N++R +
Sbjct  119  Y----RGPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLF  174

Query  182  TILGRNAGYDGVLSVGRVQTPVLGLVVRRDEEIESFIPKDFFEVKAHIVTPADERFIALW  241
            T+LGR+AGYDGVLSVGRVQTP L+LVV RD EI  F++  F  +   + T +++ F+A W
Sbjct  175  TLLGRQAGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLST-GGHSFLATW  233

Query  242  QPSDSCESYQDEEGRLLHRPLAEHVVNRI-TGQPALVTSYNDKRESETAPLPFSLSTLQI  300
             ++D+C    D+ GR L+++ A++  +R+  + +A V +    R  E++PLPF L+TLQ 
Sbjct  234  IAADGCS---DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQD  290

Query  301  EAAKRFGLSAQQVLDICQRLYETHKLITYPRSDCRYLPEEHFAGRHSVLNAISLHQSDLL  360
              +++++L  Q+ LDI Q LYETHK  TYPRSD  YLPE  +A   +VL A+   ++ L 
Sbjct  291  VCSRQLALDVQETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLR  350

Query  361  P-LEVMDSDRRNRCWDDKKVDAHHAIIPTARASKVNLTTDEG-KVYRLVAQQYLMQFCPD  418
            P LE +D  +R+R W+D KV AHH+IIPT  ++++   +D +  VYRL+  +YL QF P+
Sbjct  351  PLLEQLDRTQRSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPH  410

Query  419  AQFRKCVIELDIAGGKFIAKARFLAEAGWRTLLGSKERDE-ENEGAP----LPVVAKGAE  473
             +F +   +L  +G  + A ++ +  +GW+ +L++ E D+ + E+ P    LP +  G  
Sbjct  411  YEFDRTTAQLLCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREG--  468

Query  474  LLCERGEVVER--QTQPPRPFTDASLLSAMTGIARFVQDKELKKVLRATDGLGTEATRAG  531
            L C+  +V  +  +TQPP+P+T++ L+ AM G+A++V D  LK+ L+ T G+GTEATRA+
Sbjct  469  LSCQVNHVDLKALKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRAS  528

Query  532  IIELLFKRTFLFKKGRYIHASPAGRALIHALPDIAARPDMTAHWESTLTQISEKNCRYQD  591
            II  L+ R +L+KKGR ++AS A+  LI+A+P   + P+ TA WE +L  I   +   + 
Sbjct  529  IIKGLLERGYLLKKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLET  588

Query  592  FMQPLVMTLQDLISQAKQNRSPQVFRGLPVGPS  624
            F+      + +L+   +Q R++ +   LP GP+
Sbjct  589  FVAKQSTWITQLV---QQYRAATLAIKLPEGPA  618

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  380 bits (1428),  Expect = 1e-106, Method: Compositional matrix adjust.
 Identities = 257/633 (41%), Positives = 417/633 (66%), Gaps = 25/633 (3%)

Query  1    MRLFIAEKPSLARAIADILPKPHRRGDGFIACGNDQMVTWCVGHLLEQAQPDAYDSRYAR  60
            MRLF+ EKPS ++ IA +L   +R ++ +   G + +VTWC+GHL+E A P+AY+ +Y R
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYN--GAGTVVTWCIGHLIEAAPPEAYGEQYKR  58

Query  61   WSLADLPIIPEKWQLQPRPSVSKQLNVIKQLLQQADEVVHAGDPDREGQLLVDEVLDYLG  120
            WSL +LPIIPE+W+++P+++ + QL+++KQL+ QA E+V A D+DREG+++  E++D  G
Sbjct  59   WSLEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCG  118

Query  121  LAAEKRQNVRRCLINDLNPQAVERAVERLRYNREFIPLCVSALARARADWLYGINMTRAY  180
                 R  ++R  ++ LN  ++ +A+  L+ + E +PL  +ALAR+RADWL G+N++R +
Sbjct  119  Y----RGPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLF  174

Query  181  TILGRNAGYDGVLSVGRVQTPVLGLVVRRDEEIESFIPKDFFEVKAHIVTPADERFIALW  240
            T+LGR+AGYDGVLSVGRVQTP L+LVV RD EI  F++  F  +   + T +++ F+A W
Sbjct  175  TLLGRQAGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLST-GGHSFLATW  233

Query  241  QPSDSCESYQDEEGRLLHRPLAEHVVNRI-TGQPALVTSYNDKRESETAPLPFSLSTLQI  299
             ++D+C    D+ GR L+++ A++  +R+  + +A V +    R  E++PLPF L+TLQ 
Sbjct  234  IAADGCS---DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQD  290

Query  300  EAAKRFGLSAQQVLDICQRLYETHKLITYPRSDCRYLPEEHFAGRHSVLNAISLHQSDLL  359
              +++++L  Q+ LDI Q LYETHK  TYPRSD  YLPE  +A   +VL A+   ++ L 
Sbjct  291  VCSRQLALDVQETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLR  350

Query  360  P-LEVMDSDRRNRCWDDKKVDAHHAIIPTARASKVNLTTDEG-KVYRLVAQQYLMQFCPD  417
            P LE +D  +R+R W+D KV AHH+IIPT  ++++   +D +  VYRL+  +YL QF P+
Sbjct  351  PLLEQLDRTQRSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPH  410

Query  418  AQFRKCVIELDIAGGKFIAKARFLAEAGWRTLLGSKERDE-ENEGAP----LPVVAKGAE  472
             +F +   +L  +G  + A ++ +  +GW+ +L++ E D+ + E+ P    LP +  G  
Sbjct  411  YEFDRTTAQLLCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREG--  468

Query  473  LLCERGEVVER--QTQPPRPFTDASLLSAMTGIARFVQDKELKKVLRATDGLGTEATRAG  530
            L C+  +V  +  +TQPP+P+T++ L+ AM G+A++V D  LK+ L+ T G+GTEATRA+
Sbjct  469  LSCQVNHVDLKALKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRAS  528

Query  531  IIELLFKRTFLFKKGRYIHASPAGRALIHALPDIAARPDMTAHWESTLTQISEKNCRYQD  590
            II  L+ R +L+KKGR ++AS A+  LI+A+P   + P+ TA WE +L  I   +   + 
Sbjct  529  IIKGLLERGYLLKKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLET  588

Query  591  FMQPLVMTLQDLISQAKQNRSPQVFRGLPVGPS  623
            F+      + +L+   +Q R++ +   LP GP+
Sbjct  589  FVAKQSTWITQLV---QQYRAATLAIKLPEGPA  618

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  380 bits (1430),  Expect = 9e-107, Method: Compositional matrix adjust.
 Identities = 253/623 (41%), Positives = 408/623 (66%), Gaps = 26/623 (4%)

Query  1    MRLFIAEKPSLGRAIADVLPKPHRKGDGYIECGNGQVVTWCIGHLLEQAQPDVYDSRYAR  60
            MRLF+ EKPS G+ IA VL   +R ++ Y   G G VVTWCIGHL+E A P+ Y+ +Y R
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYN--GAGTVVTWCIGHLIEAAPPEAYGEQYKR  58

Query  61   WNLTDLPIVPEKWQLQPKPSVTKQLNVIKRLLGEAQEVIHAGDPDREGQLLVDEVLD---  117
            W+L +LPI+PE+W+++PK++ + QL+++K+L+G+A E++ A D+DREG+++  E++D   
Sbjct  59   WSLEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCG  118

Query  118  YLQLAPEKRQQVQRCLINDLNPQAVERAINRLRANSEFVPLCVSALARARADWLYGINMT  177
            Y       R  +QR  ++ LN  ++ +A+  L+++SE +PL  +ALAR+RADWL G+N++
Sbjct  119  Y-------RGPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLS  171

Query  178  RAYTLLGRNAGYQGVLSVGRVQTPVLGLVVRRDEEIENFVAKDFFDVKAHIVTPQEERFV  237
            R +TLLGR+AGY+GVLSVGRVQTP L+LVV RD EI  FV+  F  +   + T   + F+
Sbjct  172  RLFTLLGRQAGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTG-GHSFL  230

Query  238  ATWVPSEACEPYQDEEGRLLHRPLAEHVVKRIE-GQPALVTGYNDKRDSEPAPLPFSLSA  296
            ATW+++++C    D+ GR L+++ A++   R+  + +A V +    R  E++PLPF L++
Sbjct  231  ATWIAADGCS---DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGT  287

Query  297  LQIEAAKRFGFSAQNVLDICQKLYETHKLITYPRSDSRYLPEEHFAGRHAVLNAIAVHAA  356
            LQ   ++++++  Q+ LDI Q LYETHK  TYPRSDS YLPE  +A   AVL A+    +
Sbjct  288  LQDVCSRQLALDVQETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDP  347

Query  357  DLLP-QPVMDPEIRNRCWDDKKVDAHHAIIPTARSSQV-KLTDNEAKVYHLIARQYLMQF  414
             L P    +D   R+R W+D KV AHH+IIPT  ++++  ++D+   VY+LI  +YL QF
Sbjct  348  SLRPLLEQLDRTQRSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQF  407

Query  415  CPDAVFRKCQIDLEIANGKFVAKARFLAEAGWRTLLGSKERDEENDGTPLP----VVAKD  470
             P+  F +   +L  +   + A ++ +  +GW+ +L++ E  ++ DG ++P    + A  
Sbjct  408  LPHYEFDRTTAQLLCGGQTLQAVGKQVIIPGWHQVLAGPE-ADNADGEAVPRSQVLPALR  466

Query  471  DELLCEKGEVVER--QTQPPRHFTDATLLSAMTGIARFVQDKDLKKILRATDGLGTEATR  528
            + L C+  +V  +  +TQPP+ +T++ L+ AM G+A++V D  LK+ L+ T G+GTEATR
Sbjct  467  EGLSCQVNHVDLKALKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATR  526

Query  529  AGIIELLFKRGFLTKKGRYIHSSDAGRALIHSLPEMAARPDMTAHWESVLTQISEKQCRY  588
            A+II  L+ RG+L KKGR +++SDA+  LI+++P   + P+ TA WE  L  I   +   
Sbjct  527  ASIIKGLLERGYLLKKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTL  586

Query  589  QDFMQPLVGTLFQLIDQARSTPV  611
            + F+      + QL++Q R++ +
Sbjct  587  ETFVAKQSTWITQLVQQYRAATL  609

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  380 bits (1430),  Expect = 9e-107, Method: Compositional matrix adjust.
 Identities = 253/623 (41%), Positives = 408/623 (66%), Gaps = 26/623 (4%)

Query  1    MRLFIAEKPSLGRAIADVLPKPHRKGDGYIECGNGQVVTWCIGHLLEQAQPDVYDSRYAR  60
            MRLF+ EKPS G+ IA VL   +R ++ Y   G G VVTWCIGHL+E A P+ Y+ +Y R
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYN--GAGTVVTWCIGHLIEAAPPEAYGEQYKR  58

Query  61   WNLTDLPIVPEKWQLQPKPSVTKQLNVIKRLLGEAQEVIHAGDPDREGQLLVDEVLD---  117
            W+L +LPI+PE+W+++PK++ + QL+++K+L+G+A E++ A D+DREG+++  E++D   
Sbjct  59   WSLEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCG  118

Query  118  YLQLAPEKRQQVQRCLINDLNPQAVERAINRLRANSEFVPLCVSALARARADWLYGINMT  177
            Y       R  +QR  ++ LN  ++ +A+  L+++SE +PL  +ALAR+RADWL G+N++
Sbjct  119  Y-------RGPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLS  171

Query  178  RAYTLLGRNAGYQGVLSVGRVQTPVLGLVVRRDEEIENFVAKDFFDVKAHIVTPQEERFV  237
            R +TLLGR+AGY+GVLSVGRVQTP L+LVV RD EI  FV+  F  +   + T   + F+
Sbjct  172  RLFTLLGRQAGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTG-GHSFL  230

Query  238  ATWVPSEACEPYQDEEGRLLHRPLAEHVVKRIE-GQPALVTGYNDKRDSEPAPLPFSLSA  296
            ATW+++++C    D+ GR L+++ A++   R+  + +A V +    R  E++PLPF L++
Sbjct  231  ATWIAADGCS---DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGT  287

Query  297  LQIEAAKRFGFSAQNVLDICQKLYETHKLITYPRSDSRYLPEEHFAGRHAVLNAIAVHAA  356
            LQ   ++++++  Q+ LDI Q LYETHK  TYPRSDS YLPE  +A   AVL A+    +
Sbjct  288  LQDVCSRQLALDVQETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDP  347

Query  357  DLLP-QPVMDPEIRNRCWDDKKVDAHHAIIPTARSSQV-KLTDNEAKVYHLIARQYLMQF  414
             L P    +D   R+R W+D KV AHH+IIPT  ++++  ++D+   VY+LI  +YL QF
Sbjct  348  SLRPLLEQLDRTQRSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQF  407

Query  415  CPDAVFRKCQIDLEIANGKFVAKARFLAEAGWRTLLGSKERDEENDGTPLP----VVAKD  470
             P+  F +   +L  +   + A ++ +  +GW+ +L++ E  ++ DG ++P    + A  
Sbjct  408  LPHYEFDRTTAQLLCGGQTLQAVGKQVIIPGWHQVLAGPE-ADNADGEAVPRSQVLPALR  466

Query  471  DELLCEKGEVVER--QTQPPRHFTDATLLSAMTGIARFVQDKDLKKILRATDGLGTEATR  528
            + L C+  +V  +  +TQPP+ +T++ L+ AM G+A++V D  LK+ L+ T G+GTEATR
Sbjct  467  EGLSCQVNHVDLKALKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATR  526

Query  529  AGIIELLFKRGFLTKKGRYIHSSDAGRALIHSLPEMAARPDMTAHWESVLTQISEKQCRY  588
            A+II  L+ RG+L KKGR +++SDA+  LI+++P   + P+ TA WE  L  I   +   
Sbjct  527  ASIIKGLLERGYLLKKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTL  586

Query  589  QDFMQPLVGTLFQLIDQARSTPV  611
            + F+      + QL++Q R++ +
Sbjct  587  ETFVAKQSTWITQLVQQYRAATL  609

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  379 bits (1426),  Expect = 2e-106, Method: Compositional matrix adjust.
 Identities = 262/647 (41%), Positives = 430/647 (67%), Gaps = 24/647 (3%)

Query  1    MRLFIAEKPSLGRAIADVLPKPHRRADGYIQCGDGDVVTWCVGHLLEQAEPDAYDARYAR  60
            MRLF+ EKPS G+ IA VL   +R ++ Y   G G VVTWC+GHL+E A P+AY+ +Y R
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYN--GAGTVVTWCIGHLIEAAPPEAYGEQYKR  58

Query  61   WNLVDLPIVPQKWQLRPKASSAKQLKVIERLLRDAQQVVHAGDPDREGQLLVDEVLDFLA  120
            W+L +LPI+P++W++ PKA++A QLK++ +L+ +A ++V A D+DREG+++  E++D+ +
Sbjct  59   WSLEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCG  118

Query  121  LAPEKRRQVQRCLINDLNPQAVARALERLRDNHEFMPLCVSALARARADWLYGINMTRAY  180
                 R  +QR  ++ LN  ++ +AL  L+ + E +PL  +ALAR+RADWL G+N++R +
Sbjct  119  Y----RGPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLF  174

Query  181  TLLGRNAGYNGVLSVGRVQTPVLGLVVRRDEEIAHFVAKDYYEVRAHIVTPSGERFWAQW  240
            TLLGR+AGY+GVLSVGRVQTP L+LVV RD EIA+FV+  +  +   + T +G+ F A W
Sbjct  175  TLLGRQAGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLST-GGHSFLATW  233

Query  241  QPSEACEPHQDEEGRLLNRALAEHVIARIQ-DKPARVTGYNDKRESEVAPLPFSLSALQI  299
             ++++C    D+ GR L++A A++   R++   +A+V +    R  E +PLPF L++LQ 
Sbjct  234  IAADGCS---DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQD  290

Query  300  EAAKRFAMSAQQVLDICQRLYETHKLLTYPRSDSRHLPEEHFAGRHAVMAAIATHAPTL-  358
              ++++A+  Q+ LDI Q LYETHK  TYPRSDS  LPE  +A   AV+AA+ T  P+L 
Sbjct  291  VCSRQLALDVQETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLR  350

Query  359  ANLESVDVQRRNRCWDDNKVDAHHAIIPTARAGGV-TLNEDERNIYQLVARQYLMQFCPD  417
            + LE +D  +R+R W+D+KV AHH+IIPT  ++ + ++++    +Y+L+  +YL QF P+
Sbjct  351  PLLEQLDRTQRSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPH  410

Query  418  AQYRKCVIDLEIEGGGFIAKARFLSQAGWRALLGAKERDDED-EGMP----LPVVARDDL  472
             ++ +   +L   G  + A ++ +  +GW+ +L++ E D+ D E++P    LP + R++ 
Sbjct  411  YEFDRTTAQLLCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPAL-REG-  468

Query  473  LHCE--RGELMARQTQPPRHFTDATLLSAMTGIARFVQDKSLKKILRATDGLGTEATRAG  530
            L C+  + +L A +TQPP+ +T++ L+ AM G+A++V D  LK+ L+ T G+GTEATRA+
Sbjct  469  LSCQVNHVDLKALKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRAS  528

Query  531  IIELLFRRGFLHKKGRYIHASQTGSALIHCLPEMAGRPDMTAHWESTLTKISERGCRYQD  590
            II  L+ RG+L KKGR ++AS++++ LI+ +P     P+ TA WE +L  I   +   + 
Sbjct  529  IIKGLLERGYLLKKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLET  588

Query  591  FMHPLVETLQQLIHQARTAVNPRAFRDLP--PIENGRSRRTKGTTAS  635
            F+      + QL++Q R+A  +  + + P  P+  + +R+  G T++
Sbjct  589  FVAKQSTWITQLVQQYRAATLAIKLPEGPACPLCGSATRQRTGKTGP  635

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  379 bits (1424),  Expect = 3e-106, Method: Compositional matrix adjust.
 Identities = 256/623 (42%), Positives = 411/623 (66%), Gaps = 26/623 (4%)

Query  1    MRLFIAEKPSLGRAIADVLPKPHRKGDGYIECGNGQVVTWCIGHLLEQAQPDVYDGRYAR  60
            MRLF+ EKPS G+ IA VL   +R ++ Y   G G VVTWCIGHL+E A P+ Y+ +Y R
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYN--GAGTVVTWCIGHLIEAAPPEAYGEQYKR  58

Query  61   WNLLDLPIVPEKWQLQPKPSVTKQLNVIKRLLGDAQEVIHAGDPDREGQLLVDEVLD---  117
            W+L +LPI+PE+W+++PK++ + QL+++K+L+G+A E++ A D+DREG+++  E++D   
Sbjct  59   WSLEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCG  118

Query  118  YLQLAPEKRQQVQRCLINDLNPQAVERAIARLRANSEFIPLCVSALARARADWLYGINMT  177
            Y       R  +QR  ++ LN  ++ +A++ L+++SE +PL  +ALAR+RADWL G+N++
Sbjct  119  Y-------RGPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLS  171

Query  178  RAYTLLGRNAGYQGVLSVGRVQTPVLGLVVRRDEEIENFVAKDFFDVKAHIVTPKDERFV  237
            R +TLLGR+AGY+GVLSVGRVQTP L+LVV RD EI  FV+  F  +   + T  ++ F+
Sbjct  172  RLFTLLGRQAGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTG-GHSFL  230

Query  238  ATWVPSDACEPYQDEEGRLLHRPLAEHVVARIE-GQPARVTAYNDKRDSEPAPLPFSLST  296
            ATW+++D+C    D+ GR L+++ A++   R+  + +A+V A    R  E++PLPF L+T
Sbjct  231  ATWIAADGCS---DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGT  287

Query  297  LQIEAAKRFGFSAQNVLDICQKLYETHKLITYPRSDSRYLPEEHFAGRHAVLNAIAVHAA  356
            LQ   ++++++  Q+ LDI Q LYETHK  TYPRSDS YLPE  +A   AVL A+    +
Sbjct  288  LQDVCSRQLALDVQETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDP  347

Query  357  DLLP-QPAVDPEIRNRCWDDKKVDAHHAIIPTARSSQV-KLSDNEEKVYGLIARQYLMQF  414
             L P    +D   R+R W+D KV AHH+IIPT  ++++  +SD+   VY LI  +YL QF
Sbjct  348  SLRPLLEQLDRTQRSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQF  407

Query  415  CPDAVFRKCQIDLDIANGKFVAKARFLAEAGWRALLGNKERDEENDGTPLP----VVAKD  470
             P+  F +   +L  +   + A ++ +  +GW+ +L+  E  ++ DG ++P    + A  
Sbjct  408  LPHYEFDRTTAQLLCGGQTLQAVGKQVIIPGWHQVLAGPE-ADNADGEAVPRSQVLPALR  466

Query  471  DELLCEKGEVVER--QTQPPRYFTDATLLSAMTGIARFVQDKELKKILRATDGLGTEATR  528
            + L C+  +V  +  +TQPP+ +T++ L+ AM G+A++V D  LK+ L+ T G+GTEATR
Sbjct  467  EGLSCQVNHVDLKALKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATR  526

Query  529  AGIIELLFKRGFLVKKGRYIHSTDAGRALIHSLPEMAARPDMTAHWESVLTQISEKQCRY  588
            A+II  L+ RG+L+KKGR ++++DA+  LI+++P   + P+ TA WE  L  I   +   
Sbjct  527  ASIIKGLLERGYLLKKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTL  586

Query  589  QDFMQPLVATLYQLIEQARSTPV  611
            + F+    + + QL++Q R++ +
Sbjct  587  ETFVAKQSTWITQLVQQYRAATL  609

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  379 bits (1423),  Expect = 3e-106, Method: Compositional matrix adjust.
 Identities = 257/633 (41%), Positives = 417/633 (66%), Gaps = 25/633 (3%)

Query  2    MRLFIAEKPSLARAIADILPKPHRRGDGFIACGNDQMVTWCVGHLLEQAQPDAYDSRYAR  61
            MRLF+ EKPS ++ IA +L   +R ++ +   G + +VTWC+GHL+E A P+AY+ +Y R
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYN--GAGTVVTWCIGHLIEAAPPEAYGEQYKR  58

Query  62   WSLADLPIIPEKWQLQPRPSVSKQLNVIKQLLQQADEVVHAGDPDREGQLLVDEVLDYLG  121
            WSL +LPIIPE+W+++P+++ + QL+++KQL+ QA E+V A D+DREG+++  E++D  G
Sbjct  59   WSLEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCG  118

Query  122  LAAEKRQNVRRCLINDLNPQAVERAVERLRYNREFIPLCVSALARARADWLYGINMTRAY  181
                 R  ++R  ++ LN  ++ +A+  L+ + E +PL  +ALAR+RADWL G+N++R +
Sbjct  119  Y----RGPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLSRLF  174

Query  182  TILGRNAGYDGVLSVGRVQTPVLGLVVRRDEEIESFIPKDFFEVKAHIVTPADERFIALW  241
            T+LGR+AGYDGVLSVGRVQTP L+LVV RD EI  F++  F  +   + T +++ F+A W
Sbjct  175  TLLGRQAGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLST-GGHSFLATW  233

Query  242  QPSDSCESYQDEEGRLLHRPLAEHVVNRI-TGQPALVTSYNDKRESETAPLPFSLSTLQI  300
             ++D+C    D+ GR L+++ A++  +R+  + +A V +    R  E++PLPF L+TLQ 
Sbjct  234  IAADGCS---DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTERVREAPPLPFDLGTLQD  290

Query  301  EAAKRFGLSAQQVLDICQRLYETHKLITYPRSDCRYLPEEHFAGRHSVLNAISLHQSDLL  360
              +++++L  Q+ LDI Q LYETHK  TYPRSD  YLPE  +A   +VL A+   ++ L 
Sbjct  291  VCSRQLALDVQETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTDPSLR  350

Query  361  P-LEVMDSDRRNRCWDDKKVDAHHAIIPTACASKVNLTTDEG-KVYRLVAQQYLMQFCPD  418
            P LE +D  +R+R W+D KV AHH+IIPT  ++++   +D +  VYRL+  +YL QF P+
Sbjct  351  PLLEQLDRTQRSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQFLPH  410

Query  419  AQFRKCVIELDIAGGKFIAKARFLAEAGWRTLLGSKERDE-ENEGAP----LPVVAKGAE  473
             +F +   +L  +G  + A ++ +  +GW+ +L++ E D+ + E+ P    LP +  G  
Sbjct  411  YEFDRTTAQLLCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALREG--  468

Query  474  LLCERGEVVER--QTQPPRPFTDASLLSAMTGIARFVQDKELKKVLRATDGLGTEATRAG  531
            L C+  +V  +  +TQPP+P+T++ L+ AM G+A++V D  LK+ L+ T G+GTEATRA+
Sbjct  469  LSCQVNHVDLKALKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATRAS  528

Query  532  IIELLFKRTFLFKKGRYIHASPAGRALIHALPDIAARPDMTAHWESTLTQISEKNCRYQD  591
            II  L+ R +L+KKGR ++AS A+  LI+A+P   + P+ TA WE +L  I   +   + 
Sbjct  529  IIKGLLERGYLLKKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTLET  588

Query  592  FMQPLVMTLQDLISQAKQNRSPQVFRGLPVGPS  624
            F+      + +L+   +Q R++ +   LP GP+
Sbjct  589  FVAKQSTWITQLV---QQYRAATLAIKLPEGPA  618

> AF440524|108|G95|24461748|AAN62317.1|Pseudomonas_aeruginosa_SG17M|-|108484..110502|topB|-|putative 
DNA topoisomerase III
Length=672

 Score =  379 bits (1423),  Expect = 4e-106, Method: Compositional matrix adjust.
 Identities = 251/623 (41%), Positives = 409/623 (66%), Gaps = 26/623 (4%)

Query  1    MRLFIAEKPSLGRAIADVLPKPHRKGDGYIECGNGQVVTWCIGHLLEQAQPDIYDSRYAR  60
            MRLF+ EKPS G+ IA VL   +R ++ Y   G G VVTWCIGHL+E A P+ Y+ +Y R
Sbjct  1    MRLFLCEKPSQGKDIARVLGAGQRGSGCYN--GAGTVVTWCIGHLIEAAPPEAYGEQYKR  58

Query  61   WNLNDLPIVPEKWQLQPKPSVTKQLNVIKRLLGDAEEVIHAGDPDREGQLLVDEVLD---  117
            W+L++LPI+PE+W+++PK++ + QL+++K+L+G+A E++ A D+DREG+++  E++D   
Sbjct  59   WSLEQLPIIPERWRVEPKAATAAQLKIVKQLVGQASELVIATDADREGEMIAREIIDLCG  118

Query  118  YLQLAPEKRQQVQRCLINDLNPQAVERAINRLRANSEFVPLCVSALARARADWLYGINMT  177
            Y       R  +QR  ++ LN  ++ +A+  L+++SE +PL  +ALAR+RADWL G+N++
Sbjct  119  Y-------RGPIQRLWLSALNDASIRKALGALKPSSEALPLYAAALARSRADWLVGMNLS  171

Query  178  RAYTLLGRNAGYQGVLSVGRVQTPVLGLVVRRDEEIENFVAKDFFDVKAHIVTPQEERFV  237
            R +TLLGR+AGY+GVLSVGRVQTP L+LVV RD EI  FV+  F  +   + T   + F+
Sbjct  172  RLFTLLGRQAGYDGVLSVGRVQTPTLALVVTRDREIARFVSVPFWSIEVGLSTG-GHSFL  230

Query  238  ATWVPSEACEPYQDEEGRLLHRPLAEHVVK--RIEGQPAIVTGYNDKRDSEPAPLPFSLS  295
            ATW+++++C    D+ GR L+++ A++     R+ G + +V+   + R  E++PLPF L+
Sbjct  231  ATWIAADGCS---DDAGRCLQQATAQQAADRLRVAGSAQVVAVTTE-RVREAPPLPFDLG  286

Query  296  ALQIEAAKRFGFSAQNVLDICQKLYETHKLITYPRSDSRYLPEEHFAGRHAVLNAIAVHA  355
            +LQ   ++++++  Q+ LDI Q LYETHK  TYPRSDS YLPE  +A   AVL A+    
Sbjct  287  TLQDVCSRQLALDVQETLDIAQALYETHKATTYPRSDSGYLPESMLAEVPAVLAAMLTTD  346

Query  356  ADLLP-QPVVDPEIRNRCWDDKKVDAHHAIIPTVRSSQV-KLTDNEAKVYTLIARQYLMQ  413
            + L P    +D   R+R W+D KV AHH+IIPT+ ++++  ++D+   VY LI  +YL Q
Sbjct  347  PSLRPLLEQLDRTQRSRAWNDSKVSAHHGIIPTLEPANLAAISDKALAVYRLIRAHYLAQ  406

Query  414  FCPDAVFRKCQIDLEIANGKFVAKARFLAEAGWRTLLGSKERDE-ENDGTPLPVVAKG--  470
            F P+  F +   +L  +   + A ++ +  +GW+ +L++ E D+ + ++ P + V  +  
Sbjct  407  FLPHYEFDRTTAQLLCGGQTLQAVGKQVIIPGWHQVLAGPEADNADGEAVPRSQVLPALR  466

Query  471  DELLCERGEVVER--QTQPPRHFTDATLLSAMTGIARFVQDKDLKKILRATDGLGTEATR  528
            + L C+  +V  +  +TQPP+ +T++ L+ AM G+A++V D  LK+ L+ T G+GTEATR
Sbjct  467  EGLSCQVNHVDLKALKTQPPKPYTQGDLIKAMKGVAKLVTDPRLKQKLKETTGIGTEATR  526

Query  529  AGIIELLFKRGFLSKKGRYIHSSEAGRALIHSLPEMAGRPDMTAHWESVLTQISEKQCRY  588
            A+II  L+ RG+L KKGR +++S+A+  LI+++P     P+ TA WE  L  I   +   
Sbjct  527  ASIIKGLLERGYLLKKGRTVRASDAAGRLIDAVPAAITDPGTTAVWEQALDMIEAGDMTL  586

Query  589  QDFMQPLVGTLYQLIDQARSTPV  611
            + F+      + QL++Q R++ +
Sbjct  587  ETFVAKQSTWITQLVQQYRAATL  609