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Homologs of SE1482 gene of NC_004461_P2

protein-level

Hit (GenBank Accn)

Product

Source Genome

Eval.

Ident.(%)

1) SE1482
( NP_765037.1 )

DNA topoisomerase III topB

NC_004461
(Staphylococcus epidermidis ATCC 12228)

0.0

100

2) MCCL_plsB0013
( YP_002559344.1 )

hypothetical protein

NC_011996
(Macrococcus caseolyticus JCSC5402)

2e-150

3) TEH_23560
( YP_004887847.1 )

putative DNA topoisomerase III

NC_016052
(Tetragenococcus halophilus NBRC 12172)

3e-99

• Sequence Alignments

1) SE1482 in NC_004461


> NC_004461_P2|10|G10|27468400|NP_765037.1|Staphylococcus_epidermidis_ATCC_12228|-|8598..10754|-|SE1482|DNA 
topoisomerase III 
topB
Length=718

 Score = 1015 bits (3846),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 718/718 (100%), Positives = 718/718 (100%), Gaps = 0/718 (0%)

Query  1    MTILIIAEKPNQVKKYVEALGNSFNNKDGYIELESELFDKKVIVTWCVGHLIQLAHMEDY  60
            MTILIIAEKPNQVKKYVEALGNSFNNKDGYIELESELFDKKVIVTWCVGHLIQLAHMEDY
Sbjct  1    MTILIIAEKPNQVKKYVEALGNSFNNKDGYIELESELFDKKVIVTWCVGHLIQLAHMEDY  60

Query  61   DSNLKQWSKDTLPFIPEDFIFKVSDYGSKQFKIIKELCENLNSDSEIIIATDPDREGEAI  120
            DSNLKQWSKDTLPFIPEDFIFKVSDYGSKQFKIIKELCENLNSDSEIIIATDPDREGEAI
Sbjct  61   DSNLKQWSKDTLPFIPEDFIFKVSDYGSKQFKIIKELCENLNSDSEIIIATDPDREGEAI  120

Query  121  ARYVLNKIPCTKNLKLKRLWANTQEPEGLKLAFKNLKDADDTYRFYLEAEARSIADWLVG  180
            ARYVLNKIPCTKNLKLKRLWANTQEPEGLKLAFKNLKDADDTYRFYLEAEARSIADWLVG
Sbjct  121  ARYVLNKIPCTKNLKLKRLWANTQEPEGLKLAFKNLKDADDTYRFYLEAEARSIADWLVG  180

Query  181  MNFTRYVTLEMKQLGIDEGVFSVGRVQTPTLYMVYKRNNEIKNFESKTYYEMVAKDKENE  240
            MNFTRYVTLEMKQLGIDEGVFSVGRVQTPTLYMVYKRNNEIKNFESKTYYEMVAKDKENE
Sbjct  181  MNFTRYVTLEMKQLGIDEGVFSVGRVQTPTLYMVYKRNNEIKNFESKTYYEMVAKDKENE  240

Query  241  NAVFKSEHKFDSIDefeqflnennlncecegeikeisisekRKVAPNLFKLGGIQKVANQ  300
            NAVFKSEHKFDSIDEFEQFLNENNLNCECEGEIKEISISEKRKVAPNLFKLGGIQKVANQ
Sbjct  241  NAVFKSEHKFDSIDEFEQFLNENNLNCECEGEIKEISISEKRKVAPNLFKLGGIQKVANQ  300

Query  301  KWGYTLDKTLSIVQSLYDKGYLSYPRTDCSLITHSEFEYLKDNFSSYCKLLNIEIEQKNI  360
            KWGYTLDKTLSIVQSLYDKGYLSYPRTDCSLITHSEFEYLKDNFSSYCKLLNIEIEQKNI
Sbjct  301  KWGYTLDKTLSIVQSLYDKGYLSYPRTDCSLITHSEFEYLKDNFSSYCKLLNIEIEQKNI  360

Query  361  EPRTQYVNDSKVLEHYAIIPTKQIPENDVYNNFSDDEKKIYDEVVKRTMLMFMEDYIYSE  420
            EPRTQYVNDSKVLEHYAIIPTKQIPENDVYNNFSDDEKKIYDEVVKRTMLMFMEDYIYSE
Sbjct  361  EPRTQYVNDSKVLEHYAIIPTKQIPENDVYNNFSDDEKKIYDEVVKRTMLMFMEDYIYSE  420

Query  421  TKIVLCIENVEFKLTGNVAKEQGWKLLDSENKNSKEKLLPNYKENEKLSLNLVPKELNTK  480
            TKIVLCIENVEFKLTGNVAKEQGWKLLDSENKNSKEKLLPNYKENEKLSLNLVPKELNTK
Sbjct  421  TKIVLCIENVEFKLTGNVAKEQGWKLLDSENKNSKEKLLPNYKENEKLSLNLVPKELNTK  480

Query  481  PPKYlteatlggegglMENCSKFIENEELKGNLKEVHGIGTPATRSSIVKSLIDRGYLET  540
            PPKYLTEATLGGEGGLMENCSKFIENEELKGNLKEVHGIGTPATRSSIVKSLIDRGYLET
Sbjct  481  PPKYLTEATLGGEGGLMENCSKFIENEELKGNLKEVHGIGTPATRSSIVKSLIDRGYLET  540

Query  541  KKKHLMITPKGTLLCSALENTNLVSVEMTANWESTLKDISEKGHRIRQNEFIDSIKQYIK  600
            KKKHLMITPKGTLLCSALENTNLVSVEMTANWESTLKDISEKGHRIRQNEFIDSIKQYIK
Sbjct  541  KKKHLMITPKGTLLCSALENTNLVSVEMTANWESTLKDISEKGHRIRQNEFIDSIKQYIK  600

Query  601  QMINSDNKLLKLESNDKNIEKAIEQSTICNCPKCSNGRIKKLLSKNKKLFYACSNKDCDF  660
            QMINSDNKLLKLESNDKNIEKAIEQSTICNCPKCSNGRIKKLLSKNKKLFYACSNKDCDF
Sbjct  601  QMINSDNKLLKLESNDKNIEKAIEQSTICNCPKCSNGRIKKLLSKNKKLFYACSNKDCDF  660

Query  661  IIFGMISNKNITPQIVkeiiekgktktikgFTSKAGKKFNAKLKLTEKGVEFDFNKKK  718
            IIFGMISNKNITPQIVKEIIEKGKTKTIKGFTSKAGKKFNAKLKLTEKGVEFDFNKKK
Sbjct  661  IIFGMISNKNITPQIVKEIIEKGKTKTIKGFTSKAGKKFNAKLKLTEKGVEFDFNKKK  718

2) MCCL_plsB0013 in NC_011996


> NC_004461_P2|10|G10|27468400|NP_765037.1|Staphylococcus_epidermidis_ATCC_12228|-|8598..10754|-|SE1482|DNA 
topoisomerase III 
topB
Length=718

 Score =  526 bits (1985),  Expect = 2e-150, Method: Compositional matrix adjust.
 Identities = 340/686 (50%), Positives = 505/686 (74%), Gaps = 15/686 (2%)

Query  1    MKTVIIAEKPDQAKKYGAALG-SFSRKTSYLEGKTDVFPGEVYITWCIGHLVELAPMREY  59
            M  +IIAEKP+Q KKY  ALG SF+ K +Y+E  +++F   V +TWC+GHL++LA M +Y
Sbjct  1    MTILIIAEKPNQVKKYVEALGNSFNNKDGYIELESELFDKKVIVTWCVGHLIQLAHMEDY  60

Query  60   DEKYAKWNLEDLPFLPKQFKYQ-SKYSVKDQFNSMRKLLKGLTNNDQIVIATDPDREGEA  118
            D +  +W+ + LPF+P +F ++ S Y+ K QF+ ++ L   L ++ +I+IATDPDREGEA
Sbjct  61   DSNLKQWSKDTLPFIPEDFIFKVSDYGSK-QFKIIKELCENLNSDSEIIIATDPDREGEA  119

Query  119  IAYYVLNLLG-IKDIPIKRLWANTQEPTELKNFFRKLKDGKETYRYYVEAEARGKSDYLV  177
            IA YVLN +   K++ +KRLWANTQEP  LK  F++LKD+ +TYR+Y+EAEAR+ +D LV
Sbjct  120  IARYVLNKIPCTKNLKLKRLWANTQEPEGLKLAFKNLKDADDTYRFYLEAEARSIADWLV  179

Query  178  GMNLTRLITLLLQNKGVRTDGAFSVGRVQTPTLFMVYNREKEIENFKEKIYFDLVADGKK  237
            GMN+TR +TL +++ G+  +G FSVGRVQTPTL+MVY+R++EI NF  K Y+++VA +K 
Sbjct  180  GMNFTRYVTLEMKQLGI-DEGVFSVGRVQTPTLYMVYKRNNEIKNFESKTYYEMVAKDK-  237

Query  238  DSIKYQLKSDVRLDSnnevneyinnnGL-SDIPGEVKSITVTPKTTKAPKLFKLGGIQKV  296
            ++ +  +KS+ ++DS +E ++++N+N L  +  GE+K I+++ K   AP+LFKLGGIQKV
Sbjct  238  ENENAVFKSEHKFDSIDEFEQFLNENNLNCECEGEIKEISISEKRKVAPNLFKLGGIQKV  297

Query  297  GNNKWGYSLDQTLSYVQLLYDKGFLSYPRTDSSLITTAEFEYLKNHLEDYKSLLNLTFDV  356
            +N+KWGY+LD+TLS VQ LYDKG+LSYPRTD SLIT +EFEYLK+++  Y  LLN+ ++ 
Sbjct  298  ANQKWGYTLDKTLSIVQSLYDKGYLSYPRTDCSLITHSEFEYLKDNFSSYCKLLNIEIEQ  357

Query  357  KYTEPRKTYVDNDKVLEHYAIVPTKTIPSQQQYDDLSVQEKNIYDAVVKQTLAIFADDYH  416
            K  EPR  YV++ KVLEHYAI+PTK IP ++ Y+++S +EK+IYD VVK+T+ +F +DY 
Sbjct  358  KNIEPRTQYVNDSKVLEHYAIIPTKQIPENDVYNNFSDDEKKIYDEVVKRTMLMFMEDYI  417

Query  417  YEQTKVEIVVNDVIFKTSGNTPKIQGWKNLSNDTEEEKTTTLPSFEEGEQVELSIYGKEG  476
            Y +TK+ + +++V FK +GN +K QGWK L ++  + K   LP++ E E++ L++  KE 
Sbjct  418  YSETKIVLCIENVEFKLTGNVAKEQGWKLLDSENKNSKEKLLPNYKENEKLSLNLVPKEL  477

Query  477  RTKPPSYlteatlggegglmetcgKTIEDEELRESLSA--GIGTPATRSAIVKNIIDKGY  534
             TKPP YLTEATLGGEGGLME C+K IE+EEL+ +L    GIGTPATRS+IVK++ID+GY
Sbjct  478  NTKPPKYLTEATLGGEGGLMENCSKFIENEELKGNLKEVHGIGTPATRSSIVKSLIDRGY  537

Query  535  ITVDKKKLRTTEKGRLLCSALEGSLISSAEMTGKWEEKLKFISD--GKETQQNFIEGIEI  592
            +   KK L  T KG LLCSALE + + S EMT++WE  LK IS+   +  Q++FI++I  
Sbjct  538  LETKKKHLMITPKGTLLCSALENTNLVSVEMTANWESTLKDISEKGHRIRQNEFIDSIKQ  597

Query  593  FIQQLFKDIPAMVNENVKTSTLESVKQSEGKGLGICPKCNKGYI-KHIKTNKYDFYACSE  651
            +I+Q+++    +++ + +   +E  K  E   +  CPKC++G I K +  NK  FYACS+
Sbjct  598  YIKQMINSDNKLLKLESNDKNIE--KAIEQSTICNCPKCSNGRIKKLLSKNKKLFYACSN  655

Query  652  K-CGFTINSVIASKKLSESNIKQLIN  676
            K C+F I ++I++K+++   +K++I+
Sbjct  656  KDCDFIIFGMISNKNITPQIVKEIIE  681

3) TEH_23560 in NC_016052


> NC_004461_P2|10|G10|27468400|NP_765037.1|Staphylococcus_epidermidis_ATCC_12228|-|8598..10754|-|SE1482|DNA 
topoisomerase III 
topB
Length=718

 Score =  356 bits (1336),  Expect = 3e-99, Method: Compositional matrix adjust.
 Identities = 234/582 (41%), Positives = 388/582 (67%), Gaps = 17/582 (2%)

Query  1    MSTVILAEKPSQALAYASALKQS-TKKDGYFEIKDPLFTDETFITFGFGHLVELAEPGHY  59
            M+ +I+AEKP+Q   Y  AL +S  +KDGY+E+   LF    ++T   GHL++LA+  +Y
Sbjct  1    MTILIIAEKPNQVKKYVEALGNSFNNKDGYIELESELFDKKVIVTWCVGHLIQLAHMEDY  60

Query  60   DEKWQNWKLESLPILPDRYDFEVAKDKGKQFKIVAEL---LKKANTIIVATDSDREGENI  116
            D + ++W  ++LP++P+ + F V+   +KQFKI+ EL   L+  + II+ATD+DREGE I
Sbjct  61   DSNLKQWSKDTLPFIPEDFIFKVSDYGSKQFKIIKELCENLNSDSEIIIATDPDREGEAI  120

Query  117  AWSIIHKANAFSKDKTFKRLWINSLEKDVIRSGFQNLQPGMNYYPFYQEAQTRQIADWLI  176
            A+ +++K    +K+  +KRLW N+ E + ++ +F+NL+ + + Y FY EA++R IADWL+
Sbjct  121  ARYVLNKIPC-TKNLKLKRLWANTQEPEGLKLAFKNLKDADDTYRFYLEAEARSIADWLV  179

Query  177  GMNASPLYTLNLQQKGVQDT-FSLGRVQTPTLYLIFQRQEATENFKKEPFFEVEASIKVN  235
            GMN +   TL+++Q G+++  FS+GRVQTPTLY++++R++   NF    ++E+ A  K N
Sbjct  180  GMNFTRYVTLEMKQLGIDEGVFSVGRVQTPTLYMVYKRNNEIKNFESKTYYEMVAKDKEN  239

Query  236  QGSFKGVLSPTQHFKTQEELLAFVSSKQAKIGNQEGIIADVRTKEKKTNspslfslsslq  295
            +    +V+ + + F + +E+  F++ ++ +    EG I ++   EK+  +P+LF L+++Q
Sbjct  240  EN---AVFKSEHKFDSIDEFEQFLNENNLNCEC-EGEIKEISISEKRKVAPNLFKLGGIQ  295

Query  296  sKVNQLYKATASQTLKAMQGLYEAKLLSYPRTDTPFITENEFAYLKANFGKYSGFLGLDL  355
               NQ    T  +TL  +Q+LY+   LSYPRTD ++IT++EF YLK NF+ Y  +L +++
Sbjct  296  KVANQKWGYTLDKTLSIVQSLYDKGYLSYPRTDCSLITHSEFEYLKDNFSSYCKLLNIEI  355

Query  356  EMVQTEPRKRYVDGSKVQEHHAIIPTKQVPNESALAKMDDLQRKIYALVVKTTVAMFLPD  415
            E  + EPR +YV++SKV EH AIIPTKQ+P++    +  D ++KIY  VVK T+ MF+ D
Sbjct  356  EQKNIEPRTQYVNDSKVLEHYAIIPTKQIPENDVYNNFSDDEKKIYDEVVKRTMLMFMED  415

Query  416  YLYEETKIQTKVADLLFQSIGKTPKQEGWKILFKQQTKEEKEDVQTLPLVIIGERAEVDV  475
            Y+Y ETKI   + ++ F+  G+ +K++GWK+L   + K+ KE +  LP     E+  +++
Sbjct  416  YIYSETKIVLCIENVEFKLTGNVAKEQGWKLL-DSENKNSKEKL--LPNYKENEKLSLNL  472

Query  476  KSVEKETQPPKAFTEGTLLTA---MKTANKTVDNEEAIKILQEVEGIGTEATRASIIEAL  532
             + E +T+PPK +TE+TL      M   +K ++NEE    L+EV+GIGT ATR+SI+ +L
Sbjct  473  VPKELNTKPPKYLTEATLGGEGGLMENCSKFIENEELKGNLKEVHGIGTPATRSSIVKSL  532

Query  533  KQKEYIQVIKNKLVVTEKGKLLCQAVESQHLLTSAEMTAKWE  574
             ++ Y++  K+ L++T KG LLC A+E+ +L+ S EMTA+WE
Sbjct  533  IDRGYLETKKKHLMITPKGTLLCSALENTNLV-SVEMTANWE  573