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Homologs of cag7 gene of AY330644

protein-level

Hit (GenBank Accn)

Product

Source Genome

Eval.

Ident.(%)

1) HMPREF0462_0892
( YP_005785459.1 )

hypothetical protein

NC_017375
(Helicobacter pylori 83)

3e-178

2) HPAG1_0503
( YP_627244.1 )

cag pathogenicity island protein Y

NC_008086
(Helicobacter pylori HPAG1)

1e-175

3) K747_11670
( YP_008357562.1 )

hypothetical protein

NC_021215
(Helicobacter pylori UM032)

5e-149

4) cag7b
( YP_005783498.1 )

cag pathogenicity island protein

NC_017374
(Helicobacter pylori 2017)

2e-137

• Sequence Alignments

1) HMPREF0462_0892 in NC_017375


> AY330644|1|G1|37811886|AAR03951.1|Helicobacter_pylori_Du23:2|-|1..1653|cag7|HP0527|Cag7
Length=551

 Score =  618 bits (2335),  Expect = 3e-178, Method: Compositional matrix adjust.
 Identities = 514/551 (94%), Positives = 530/551 (97%), Gaps = 0/551 (0%)

Query  1    MNEENDKLETSKKTQQHSPQDLSNEEATEVNHFedsskeskessdHHLDNPTETQTNFDE  60
            MNEENDKLETSKKTQQ+SPQDLSNEEATEVNHFED  KESKESSD  LDNPTETQT+FD 
Sbjct  1    MNEENDKLETSKKTQQDSPQDLSNEEATEVNHFEDLLKESKESSDPYLDNPTETQTHFDG  60

Query  61   YELEETQTQIDSGGNETSESSDGSLADKLFKKARKLVDNKRPFTQQKnldeetqelneed  120
               EETQTQIDS G+ETSESS+GSLADKLFKKARKLVDNKRPFTQQK+LDEE+Q LNEED
Sbjct  61   DKSEETQTQIDSEGDETSESSNGSLADKLFKKARKLVDNKRPFTQQKSLDEEAQKLNEED  120

Query  121  dqennGYQEETQIDLIDDETSKKTQQHSPQDLSNEEATEANHFedsskeseessdNHLDN  180
            DQENN YQEETQ+DLIDDETSKKTQQ+SPQDLSNEEATE NHFED  KES ESSD  LDN
Sbjct  121  DQENNEYQEETQMDLIDDETSKKTQQDSPQDLSNEEATEVNHFEDLLKESKESSDPYLDN  180

Query  181  PTETETNFDEYELEEITNDSNDQEiikgskkkyiiggivvavliviilFSRSIFHYFIPL  240
            PTET+T+FD    EEITNDSNDQEIIKGSKKKYIIGGIVVAVLIVIILFSRSIFHYF+PL
Sbjct  181  PTETQTHFDGDKSEEITNDSNDQEIIKGSKKKYIIGGIVVAVLIVIILFSRSIFHYFMPL  240

Query  241  EDKSSRFSKDRNLYVNDEIQIRQEYNRLLKERNEKGNMIDKNLFFNDDPNRTLYNYLNIA  300
            EDKSSRFSKDRNLYVNDEIQIRQEYNRLLKERNEKGNMIDKNLFFNDDPNRTLYNYLNIA
Sbjct  241  EDKSSRFSKDRNLYVNDEIQIRQEYNRLLKERNEKGNMIDKNLFFNDDPNRTLYNYLNIA  300

Query  301  EIEDKNPLRAFYECISNGGNYEEClklikdkklqdqmkktlEAYNDCIKNAKTEEERIKC  360
            EIEDKNPLRAFYECISNGGNYEECLKLIKDKKLQDQMKKTLEAYNDCIKNAKTEEERIKC
Sbjct  301  EIEDKNPLRAFYECISNGGNYEECLKLIKDKKLQDQMKKTLEAYNDCIKNAKTEEERIKC  360

Query  361  LDLIKDENLKKSLLNQQKVQVALDCLKNAKTDEERNECLKLINDPEIREKFRKELGIQKE  420
            LDLIKDENLKKSLLNQQKVQVALDCLKNAKTDEERNECLKLINDPEIREKFRKELG+QKE
Sbjct  361  LDLIKDENLKKSLLNQQKVQVALDCLKNAKTDEERNECLKLINDPEIREKFRKELGLQKE  420

Query  421  LQEYKDCIKNAKTEAEKNECLKGLSKEAIERLKQQALDCLKNAKTDEERNECLKNIPKDL  480
            LQEYKDCIKNAKTEAEKNECLK+LSKEAIERLKQQALDCLKNAKTDEERNECLKNIP+DL
Sbjct  421  LQEYKDCIKNAKTEAEKNECLKSLSKEAIERLKQQALDCLKNAKTDEERNECLKNIPQDL  480

Query  481  QKELLADMSVKAYKDCVSRARNekekkecekLLTPEAKKKLEQQVLDCLKNAKTDEERKK  540
            QKELLADMSVKAYKDCVS+ARNEKEKKECEKLLTPEAKKKLEQQVLDCLK+AKTDEERKK
Sbjct  481  QKELLADMSVKAYKDCVSKARNEKEKKECEKLLTPEAKKKLEQQVLDCLKSAKTDEERKK  540

Query  541  CLKDLPKDLQS  551
            CLKDLPKDLQS
Sbjct  541  CLKDLPKDLQS  551


 Score =  127 bits (465),  Expect = 2e-30, Method: Compositional matrix adjust.
 Identities = 97/183 (54%), Positives = 129/183 (71%), Gaps = 17/183 (9%)

Query  396  NECLKLINDPEIREKFRKELGIQKELQEYKDCIKNAKTEAEKNECLKGLSKEAIER--LK  453
            +ECLKLI+D  ++++ +K L      + Y+DCIKNAKTE E+  CL  +  E + +  L+
Sbjct  322  EECLKLIKDKKLQDQMKKTL------EAYNDCIKNAKTEEERIKCLDLIKDENLKKSLLN  375

Query  454  QQ----ALDCLKNAKTDEERNECLK-----NIPKDLQKELLADMSVKAYKDCVSRARNek  504
            QQ    ALDCLKNAKTDEERNECLK     +I   ++KEL  +  ++ YKDC+  A+ E 
Sbjct  376  QQKVQVALDCLKNAKTDEERNECLKLINDPEIREKFRKELGLQKELQEYKDCIKNAKTEA  435

Query  505  ekkecekLLTPEAKKKLEQQVLDCLKNAKTDEERKKCLKDLPKDLQSDILAKESLKAYKD  564
            EK+EC K L+ EA  +L QQ LDCLKNAKTDEER+ CLK++P+DLQ ++LA  S+KAYKD
Sbjct  436  EKNECLKSLSKEAIERLKQQALDCLKNAKTDEERNECLKNIPQDLQKELLADMSVKAYKD  495

Query  565  CVS  567
            CVS
Sbjct  496  CVS  498

2) HPAG1_0503 in NC_008086


> AY330644|1|G1|37811886|AAR03951.1|Helicobacter_pylori_Du23:2|-|1..1653|cag7|HP0527|Cag7
Length=551

 Score =  609 bits (2301),  Expect = 1e-175, Method: Compositional matrix adjust.
 Identities = 523/551 (95%), Positives = 536/551 (98%), Gaps = 4/551 (0%)

Query  1    MNEENDKLETSKKTQQHSPQDLSNEEATEVNHFEDSLKE--ESSDNHLNNSTETQTHFDG  58
            MNEENDKLETSKKTQQ+SPQDLSNEEATEVNHFED LKE  ESSD  L+N+TETQTHFDG
Sbjct  1    MNEENDKLETSKKTQQDSPQDLSNEEATEVNHFEDLLKESKESSDPYLDNPTETQTHFDG  60

Query  59   DKSEETQTQIDsegnetsessngsLADKLFKKARKLVDNKRPFTQQKnldeetqelneed  118
            DKSEETQTQIDSEG+ETSESSNGSLADKLFKKARKLVDNKRPFTQQK+LDEE+Q LNEED
Sbjct  61   DKSEETQTQIDSEGDETSESSNGSLADKLFKKARKLVDNKRPFTQQKSLDEEAQKLNEED  120

Query  119  dqennGYQEETQTGLIDDETSKKTQQHSPQDLSNEEATEVNHFEDSLKE--ESSDNHLDN  176
            DQENN YQEETQ +LIDDETSKKTQQ+SPQDLSNEEATEVNHFED LKE  ESSD  LDN
Sbjct  121  DQENNEYQEETQMDLIDDETSKKTQQDSPQDLSNEEATEVNHFEDLLKESKESSDPYLDN  180

Query  177  PTETQTHFDGDKSEEITNDSNDQEiikgskkkyiiggivvavliviilFSRSIFHYFMPL  236
            PTETQTHFDGDKSEEITNDSNDQEIIKGSKKKYIIGGIVVAVLIVIILFSRSIFHYFMPL
Sbjct  181  PTETQTHFDGDKSEEITNDSNDQEIIKGSKKKYIIGGIVVAVLIVIILFSRSIFHYFMPL  240

Query  237  EDKSSRFSKDRNLYVNDEIQIRQEYNRLLKERNEKGNMIDKNLFFNDDPNRTLYNYLNIA  296
            EDKSSRFSKDRNLYVNDEIQIRQEYNRLLKERNEKGNMIDKNLFFNDDPNRTLYNYLNIA
Sbjct  241  EDKSSRFSKDRNLYVNDEIQIRQEYNRLLKERNEKGNMIDKNLFFNDDPNRTLYNYLNIA  300

Query  297  EIEDENPLRAFYECISNGGNYEEClklikdkklqdqmkktlEAYNDCIKNAKTEEERIKC  356
            EIED NPLRAFYECISNGGNYEECLKLIKDKKLQDQMKKTLEAYNDCIKNAKTEEERIKC
Sbjct  301  EIEDKNPLRAFYECISNGGNYEECLKLIKDKKLQDQMKKTLEAYNDCIKNAKTEEERIKC  360

Query  357  LDLIKDENLKKSLLNQQKVQVALDCLKNAKTDEERKECLKLINDPEIrekfrkelelqke  416
            LDLIKDENLKKSLLNQQKVQVALDCLKNAKTDEER+ECLKLINDPEIREKFRKEL LQKE
Sbjct  361  LDLIKDENLKKSLLNQQKVQVALDCLKNAKTDEERNECLKLINDPEIREKFRKELGLQKE  420

Query  417  lqeYKDCIKNAKTEAEKNECLKGLSKEAIERLKQQALDCLKNAKTDEERNECLKNIPQDL  476
            LQEYKDCIKNAKTEAEKNECLK+LSKEAIERLKQQALDCLKNAKTDEERNECLKNIPQDL
Sbjct  421  LQEYKDCIKNAKTEAEKNECLKSLSKEAIERLKQQALDCLKNAKTDEERNECLKNIPQDL  480

Query  477  QKELLADMSVKAYKDCVSKARNEKEKQECEKLLTPEARKKLEQQVLDCLKNAKTDEERKK  536
            QKELLADMSVKAYKDCVSKARNEKEK+ECEKLLTPEA+KKLEQQVLDCLK+AKTDEERKK
Sbjct  481  QKELLADMSVKAYKDCVSKARNEKEKKECEKLLTPEAKKKLEQQVLDCLKSAKTDEERKK  540

Query  537  CLKDLPKDLQS  547
            CLKDLPKDLQS
Sbjct  541  CLKDLPKDLQS  551


 Score =  135 bits (495),  Expect = 7e-33, Method: Compositional matrix adjust.
 Identities = 100/186 (54%), Positives = 133/186 (72%), Gaps = 17/186 (9%)

Query  393  ECLKLINDPEIrekfrkelelqkelqeYKDCIKNAKTEAEKNECLKGLSKEAIER--LKQ  450
            ECLKLI+D  ++++ +K LE       Y+DCIKNAKTE E+  CL  +  E + +  L+Q
Sbjct  323  ECLKLIKDKKLQDQMKKTLEA------YNDCIKNAKTEEERIKCLDLIKDENLKKSLLNQ  376

Query  451  Q----ALDCLKNAKTDEERNECLK-----NIPQDLQKELLADMSVKAYKDCVSKARNEKE  501
            Q    ALDCLKNAKTDEERNECLK     +I + ++KEL  +  ++ YKDC+ +A+ E E
Sbjct  377  QKVQVALDCLKNAKTDEERNECLKLINDPEIREKFRKELGLQKELQEYKDCIKNAKTEAE  436

Query  502  KQECEKLLTPEARKKLEQQVLDCLKNAKTDEERKKCLKDLPKDLQSDILAKESVKAYKDC  561
            K+EC K L+ EA  +L QQ LDCLKNAKTDEER+ CLK++P+DLQ ++LA  SVKAYKDC
Sbjct  437  KNECLKSLSKEAIERLKQQALDCLKNAKTDEERNECLKNIPQDLQKELLADMSVKAYKDC  496

Query  562  VSQAKT  567
            VS+A+ 
Sbjct  497  VSKARN  502

3) K747_11670 in NC_021215


> AY330644|1|G1|37811886|AAR03951.1|Helicobacter_pylori_Du23:2|-|1..1653|cag7|HP0527|Cag7
Length=551

 Score =  521 bits (1965),  Expect = 5e-149, Method: Compositional matrix adjust.
 Identities = 429/474 (91%), Positives = 448/474 (95%), Gaps = 0/474 (0%)

Query  139  ETSKKTQQHSPQDLSNEEATEANHFedsskeskessdHHLDNPTETKTNFDGYKSEETQT  198
            ETSKKTQQ+SPQDLSNEEATE NHFED  KESKESSD  LDNPTET+T+FDG KSEETQT
Sbjct  9    ETSKKTQQDSPQDLSNEEATEVNHFEDLLKESKESSDPYLDNPTETQTHFDGDKSEETQT  68

Query  199  QMDsggnetsessngnLADKLFKKARKLVDDKRPFTQQKILDEEIQEPNEEDDQESNGYQ  258
            Q+DS G+ETSESSNG+LADKLFKKARKLVD+KRPFTQQK LDEE Q  NEEDDQE+N YQ
Sbjct  69   QIDSEGDETSESSNGSLADKLFKKARKLVDNKRPFTQQKSLDEEAQKLNEEDDQENNEYQ  128

Query  259  EETQMDLIDDETSKKTQQHSPQDLSNEEATEANHFedsskeskessdHHLDNPTETKTNF  318
            EETQMDLIDDETSKKTQQ+SPQDLSNEEATE NHFED  KESKESSD  LDNPTET+T+F
Sbjct  129  EETQMDLIDDETSKKTQQDSPQDLSNEEATEVNHFEDLLKESKESSDPYLDNPTETQTHF  188

Query  319  DEYESEEITNDSNDQEiikgskkkyiiggivvavliviilFSRSIFHYFIPLEDKSSRFS  378
            D   SEEITNDSNDQEIIKGSKKKYIIGGIVVAVLIVIILFSRSIFHYF+PLEDKSSRFS
Sbjct  189  DGDKSEEITNDSNDQEIIKGSKKKYIIGGIVVAVLIVIILFSRSIFHYFMPLEDKSSRFS  248

Query  379  KDRNLYVNDEIQIRQEYNRLLKERNEKGNMIDKNLFFNDDPNRTLYNYLNIAEIEDKNPL  438
            KDRNLYVNDEIQIRQEYNRLLKERNEKGNMIDKNLFFNDDPNRTLYNYLNIAEIEDKNPL
Sbjct  249  KDRNLYVNDEIQIRQEYNRLLKERNEKGNMIDKNLFFNDDPNRTLYNYLNIAEIEDKNPL  308

Query  439  RAFYECISNGGNYEEClklikdkklqdqmkRTLEAYNDCIKNAKTEEERIKCLDLIKDEN  498
            RAFYECISNGGNYEECLKLIKDKKLQDQMK+TLEAYNDCIKNAKTEEERIKCLDLIKDEN
Sbjct  309  RAFYECISNGGNYEECLKLIKDKKLQDQMKKTLEAYNDCIKNAKTEEERIKCLDLIKDEN  368

Query  499  LKKSLLNQQKVQVALDCLKNAKTDEERNECLKLINDPEIREKFRKELGLQKELQEYKDCI  558
            LKKSLLNQQKVQVALDCLKNAKTDEERNECLKLINDPEIREKFRKELGLQKELQEYKDCI
Sbjct  369  LKKSLLNQQKVQVALDCLKNAKTDEERNECLKLINDPEIREKFRKELGLQKELQEYKDCI  428

Query  559  KNAKTEAEKNECLKGLSKEAIERLKQQALDCLKSAKTDEERKKMFEKYSQRLAK  612
            KNAKTEAEKNECLK+LSKEAIERLKQQALDCLK+AKTDEER+  + + +Q L K
Sbjct  429  KNAKTEAEKNECLKSLSKEAIERLKQQALDCLKNAKTDEERNECLKNIPQDLQK  482


 Score =  172 bits (637),  Expect = 4e-44, Method: Compositional matrix adjust.
 Identities = 165/196 (85%), Positives = 176/196 (90%), Gaps = 0/196 (0%)

Query  1    MNEENDKLENSKKTQQHSPQDLSNEEATEANHFedsskeskessdHHLDNPTETKTNFDG  60
            MNEENDKLE SKKTQQ+SPQDLSNEEATE NHFED  KESKESSD  LDNPTET+T+FDG
Sbjct  1    MNEENDKLETSKKTQQDSPQDLSNEEATEVNHFEDLLKESKESSDPYLDNPTETQTHFDG  60

Query  61   YKSEETQTQMDsggnetsessngnLADKLFKKARKLVDDKRPFTQQKILDEEIQEPNEED  120
             KSEETQTQ+DS G+ETSESSNG+LADKLFKKARKLVD+KRPFTQQK LDEE Q  NEED
Sbjct  61   DKSEETQTQIDSEGDETSESSNGSLADKLFKKARKLVDNKRPFTQQKSLDEEAQKLNEED  120

Query  121  DQESNGYQEETQMDLIDDETSKKTQQHSPQDLSNEEATEANHFedsskeskessdHHLDN  180
            DQE+N YQEETQMDLIDDETSKKTQQ+SPQDLSNEEATE NHFED  KESKESSD  LDN
Sbjct  121  DQENNEYQEETQMDLIDDETSKKTQQDSPQDLSNEEATEVNHFEDLLKESKESSDPYLDN  180

Query  181  PTETKTNFDGYKSEET  196
            PTET+T+FDG KSEE 
Sbjct  181  PTETQTHFDGDKSEEI  196

4) cag7b in NC_017374


> AY330644|1|G1|37811886|AAR03951.1|Helicobacter_pylori_Du23:2|-|1..1653|cag7|HP0527|Cag7
Length=551

 Score =  482 bits (1817),  Expect = 2e-137, Method: Compositional matrix adjust.
 Identities = 430/468 (92%), Positives = 445/468 (96%), Gaps = 7/468 (1%)

Query  1    MNEENDKLETSKKAQQDSPQDLSNEEATEANHFEDLLKE--ESSDNHLDNSAETKTHFDE  58
            MNEENDKLETSKK+QQDSPQDLSNEEATE NHFEDLLKE  ESSD  LDN++ET+THFD 
Sbjct  1    MNEENDKLETSKKTQQDSPQDLSNEEATEVNHFEDLLKESKESSDPYLDNPTETQTHFDG  60

Query  59   DKLEETQTQMDsggnetsessngsLADKLFKKARKLVDDKRPFTQQKSLDEETQKLneed  118
            DK EETQTQ+DS G+ETSESSNGSLADKLFKKARKLVD+KRPFTQQKSLDEE+QKLNEED
Sbjct  61   DKSEETQTQIDSEGDETSESSNGSLADKLFKKARKLVDNKRPFTQQKSLDEEAQKLNEED  120

Query  119  dqennehqeetqtdLIDDETSEKTQQDSPQDLSNEEATEANHFEDLLKESTESSDNHLDN  178
            DQENNE QEETQ DLIDDETS KTQQDSPQDLSNEEATE NHFEDLLKES ESSD  LDN
Sbjct  121  DQENNEYQEETQMDLIDDETSKKTQQDSPQDLSNEEATEVNHFEDLLKESKESSDPYLDN  180

Query  179  PTETKTQETKTHFDEDKLEEITDDSNDQEiikgskkkyiiggivvavliviilFSRSIFH  238
            PTET+T     HFD DK EEIT+DSNDQEIIKGSKKKYIIGGIVVAVLIVIILFSRSIFH
Sbjct  181  PTETQT-----HFDGDKSEEITNDSNDQEIIKGSKKKYIIGGIVVAVLIVIILFSRSIFH  235

Query  239  YFVPLEDKSSRFSKDRNLYVNDEIQIRQEYNRLLKERNEKGNMIDKNLFFNDDPNRTLYN  298
            YF+PLEDKSSRFSKDRNLYVNDEIQIRQEYNRLLKERNEKGNMIDKNLFFNDDPNRTLYN
Sbjct  236  YFMPLEDKSSRFSKDRNLYVNDEIQIRQEYNRLLKERNEKGNMIDKNLFFNDDPNRTLYN  295

Query  299  YLNIAEIEDKNPLRAFYECISNGGNYEEClklikdkklqdqmkktlEAYNDCIKNAKTEE  358
            YLNIAEIEDKNPLRAFYECISNGGNYEECLKLIKDKKLQDQMKKTLEAYNDCIKNAKTEE
Sbjct  296  YLNIAEIEDKNPLRAFYECISNGGNYEECLKLIKDKKLQDQMKKTLEAYNDCIKNAKTEE  355

Query  359  ERIKCLDLIKDENLKKSLLNQQKVQVALDCLKNAKTDEERKECLKLINDPEIrekfrkel  418
            ERIKCLDLIKDENLKKSLLNQQKVQVALDCLKNAKTDEER+ECLKLINDPEIREKFRKEL
Sbjct  356  ERIKCLDLIKDENLKKSLLNQQKVQVALDCLKNAKTDEERNECLKLINDPEIREKFRKEL  415

Query  419  elqkelqeYKDCIKNAKTEAEKNECLKGLSKEAIERLKQQALDCLNHA  466
             LQKELQEYKDCIKNAKTEAEKNECLK+LSKEAIERLKQQALDCL++A
Sbjct  416  GLQKELQEYKDCIKNAKTEAEKNECLKSLSKEAIERLKQQALDCLKNA  463


 Score = 66.3 bits (232),  Expect = 3e-12, Method: Compositional matrix adjust.
 Identities = 61/122 (50%), Positives = 83/122 (69%), Gaps = 11/122 (9%)

Query  345  EAYNDCIKNAKTEEERIKCLDLIKDENLKKSLLNQQKVQVALDCLKNAKTDEERKECLKL  404
            + Y+DCIKNAKTE E+  CL  +  E + +  L+QQ    ALDCLKNAKTDEER+ECLK 
Sbjct  422  QEYKDCIKNAKTEAEKNECLKSLSKEAIER--LKQQ----ALDCLKNAKTDEERNECLK-  474

Query  405  INDPEIrekfrkelelqkelqeYKDCIKNAKTEAEKNECLKGLSKEAIERLKQQALDCLN  464
                +I + ++KEL  +  ++ YKDC+ +A+ E EK+EC K L+ EA  +L QQ LDCL+
Sbjct  475  ----NIPQDLQKELLADMSVKAYKDCVSKARNEKEKKECEKLLTPEAKKKLEQQVLDCLK  530

Query  465  HA  466
             A
Sbjct  531  SA  532


 Score = 44.8 bits (150),  Expect = 9e-06, Method: Compositional matrix adjust.
 Identities = 42/102 (42%), Positives = 68/102 (67%), Gaps = 11/102 (10%)

Query  349  DCIKNAKTEEERIKCLDLIKDENLKKSLLNQQKVQVALDCLKNAKTDEERKECLKLINDP  408
            DC+KNAKT+EER  CL  I  ++L+K LL +  V+   DC+ +A+ + E+KEC KL+  P
Sbjct  458  DCLKNAKTDEERNECLKNI-PQDLQKELLADMSVKAYKDCVSKARNEKEKKECEKLLT-P  515

Query  409  EIrekfrkelelqkelqeYKDCIKNAKTEAEKNECLKGLSKE  450
            E + K+ +++          DC+K+AKT+ E++ CLK+L+K+
Sbjct  516  EAKKKLEQQVL---------DCLKSAKTDEERKKCLKDLPKD  548


 Score = 39.3 bits (129),  Expect = 4e-04, Method: Compositional matrix adjust.
 Identities = 31/58 (54%), Positives = 39/58 (68%), Gaps = 6/58 (10%)

Query  346  AYNDCIKNAKTEEERIKCLDLIKDENLKKSLLNQQKVQVALDCLKNAKTDEERKECLK  403
            AY+DC+ +A+ E E+  C  L+  E  KK  L+QQ     LDCLK+AKTDEERK CLK
Sbjct  492  AYKDCVSKARNEKEKKECEKLLTPEAKKK--LEQQ----VLDCLKSAKTDEERKKCLK  543