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PAthogenisity Island DataBase (PAI DB)

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Homologs of tcpA gene of AF208385

protein-level

Hit (GenBank Accn)

Product

Source Genome

Eval.

Ident.(%)

• Sequence Alignments

1) O3Y_03850 in NC_016944


> AF208385|1|G1|7637504|AAF65209.1|Vibrio_cholerae_SCE188|+|1..600|tcpA|-|toxin 
coregulated pili subunit
Length=199

 Score =  249 bits (930),  Expect = 7e-68, Method: Compositional matrix adjust.
 Identities = 154/199 (78%), Positives = 186/199 (94%), Gaps = 0/199 (0%)

Query  26   MTLLEVIIVLGIMGVVSAGVVTLAQRAIDSQNMTKAAQNLNSVQIAMTQTYRSLGNYPat  85
            MTLLEVII LGIMGVVSAGVVTLAQRAIDSQNMTKAAQNLN++Q+++TQTYRSLGNYP+T
Sbjct  1    MTLLEVIIDLGIMGVVSAGVVTLAQRAIDSQNMTKAAQNLNTIQVSLTQTYRSLGNYPTT  60

Query  86   ananaatQLANGLVSLGKVSADEAKNPFTGTAMGIFSFPRNSAANKAFAITVGGLTQAQC  145
            A+ANAA+ L+ GLVSLGK+S+DEAKNPFTG+ + I SFPRN+A+NKAFAI+V+GLTQAQC
Sbjct  61   ADANAAAALTAGLVSLGKISSDEAKNPFTGSNLNIWSFPRNGAGNKAFAISVDGLTQAQC  120

Query  146  KTLVTSVGDMFPFINVKEGAFAAVADLGDFETSVADAATGAGVIKSIAPGSANLNLTNIT  205
            KTLVTSVGDMFP+INV++ A  ++ADLGDFET+VA A+TG+G+IKSIAP S NLNLT+IT
Sbjct  121  KTLVTSVGDMFPYINVQQKASMPLADLGDFETGVAAAGTGTGIIKSIAPTSVNLNLTEIT  180

Query  206  HVEKLCTGTAPFTVAFGNS  224
            HV++LC+GT+ F+VAFGNS
Sbjct  181  HVQNLCAGTGTFSVAFGNS  199

2) tcpA in NC_012578


> AF208385|1|G1|7637504|AAF65209.1|Vibrio_cholerae_SCE188|+|1..600|tcpA|-|toxin 
coregulated pili subunit
Length=199

 Score =  249 bits (930),  Expect = 7e-68, Method: Compositional matrix adjust.
 Identities = 154/199 (78%), Positives = 186/199 (94%), Gaps = 0/199 (0%)

Query  26   MTLLEVIIVLGIMGVVSAGVVTLAQRAIDSQNMTKAAQNLNSVQIAMTQTYRSLGNYPat  85
            MTLLEVII LGIMGVVSAGVVTLAQRAIDSQNMTKAAQNLN++Q+++TQTYRSLGNYP+T
Sbjct  1    MTLLEVIIDLGIMGVVSAGVVTLAQRAIDSQNMTKAAQNLNTIQVSLTQTYRSLGNYPTT  60

Query  86   ananaatQLANGLVSLGKVSADEAKNPFTGTAMGIFSFPRNSAANKAFAITVGGLTQAQC  145
            A+ANAA+ L+ GLVSLGK+S+DEAKNPFTG+ + I SFPRN+A+NKAFAI+V+GLTQAQC
Sbjct  61   ADANAAAALTAGLVSLGKISSDEAKNPFTGSNLNIWSFPRNGAGNKAFAISVDGLTQAQC  120

Query  146  KTLVTSVGDMFPFINVKEGAFAAVADLGDFETSVADAATGAGVIKSIAPGSANLNLTNIT  205
            KTLVTSVGDMFP+INV++ A  ++ADLGDFET+VA A+TG+G+IKSIAP S NLNLT+IT
Sbjct  121  KTLVTSVGDMFPYINVQQKASMPLADLGDFETGVAAAGTGTGIIKSIAPTSVNLNLTEIT  180

Query  206  HVEKLCTGTAPFTVAFGNS  224
            HV++LC+GT+ F+VAFGNS
Sbjct  181  HVQNLCAGTGTFSVAFGNS  199

3) VCD_003500 in NC_012668


> AF208385|1|G1|7637504|AAF65209.1|Vibrio_cholerae_SCE188|+|1..600|tcpA|-|toxin 
coregulated pili subunit
Length=199

 Score =  249 bits (930),  Expect = 7e-68, Method: Compositional matrix adjust.
 Identities = 154/199 (78%), Positives = 186/199 (94%), Gaps = 0/199 (0%)

Query  26   MTLLEVIIVLGIMGVVSAGVVTLAQRAIDSQNMTKAAQNLNSVQIAMTQTYRSLGNYPat  85
            MTLLEVII LGIMGVVSAGVVTLAQRAIDSQNMTKAAQNLN++Q+++TQTYRSLGNYP+T
Sbjct  1    MTLLEVIIDLGIMGVVSAGVVTLAQRAIDSQNMTKAAQNLNTIQVSLTQTYRSLGNYPTT  60

Query  86   ananaatQLANGLVSLGKVSADEAKNPFTGTAMGIFSFPRNSAANKAFAITVGGLTQAQC  145
            A+ANAA+ L+ GLVSLGK+S+DEAKNPFTG+ + I SFPRN+A+NKAFAI+V+GLTQAQC
Sbjct  61   ADANAAAALTAGLVSLGKISSDEAKNPFTGSNLNIWSFPRNGAGNKAFAISVDGLTQAQC  120

Query  146  KTLVTSVGDMFPFINVKEGAFAAVADLGDFETSVADAATGAGVIKSIAPGSANLNLTNIT  205
            KTLVTSVGDMFP+INV++ A  ++ADLGDFET+VA A+TG+G+IKSIAP S NLNLT+IT
Sbjct  121  KTLVTSVGDMFPYINVQQKASMPLADLGDFETGVAAAGTGTGIIKSIAPTSVNLNLTEIT  180

Query  206  HVEKLCTGTAPFTVAFGNS  224
            HV++LC+GT+ F+VAFGNS
Sbjct  181  HVQNLCAGTGTFSVAFGNS  199

4) VC0828 in NC_002505


> AF208385|1|G1|7637504|AAF65209.1|Vibrio_cholerae_SCE188|+|1..600|tcpA|-|toxin 
coregulated pili subunit
Length=199

 Score =  249 bits (930),  Expect = 7e-68, Method: Compositional matrix adjust.
 Identities = 154/199 (78%), Positives = 186/199 (94%), Gaps = 0/199 (0%)

Query  26   MTLLEVIIVLGIMGVVSAGVVTLAQRAIDSQNMTKAAQNLNSVQIAMTQTYRSLGNYPat  85
            MTLLEVII LGIMGVVSAGVVTLAQRAIDSQNMTKAAQNLN++Q+++TQTYRSLGNYP+T
Sbjct  1    MTLLEVIIDLGIMGVVSAGVVTLAQRAIDSQNMTKAAQNLNTIQVSLTQTYRSLGNYPTT  60

Query  86   ananaatQLANGLVSLGKVSADEAKNPFTGTAMGIFSFPRNSAANKAFAITVGGLTQAQC  145
            A+ANAA+ L+ GLVSLGK+S+DEAKNPFTG+ + I SFPRN+A+NKAFAI+V+GLTQAQC
Sbjct  61   ADANAAAALTAGLVSLGKISSDEAKNPFTGSNLNIWSFPRNGAGNKAFAISVDGLTQAQC  120

Query  146  KTLVTSVGDMFPFINVKEGAFAAVADLGDFETSVADAATGAGVIKSIAPGSANLNLTNIT  205
            KTLVTSVGDMFP+INV++ A  ++ADLGDFET+VA A+TG+G+IKSIAP S NLNLT+IT
Sbjct  121  KTLVTSVGDMFPYINVQQKASMPLADLGDFETGVAAAGTGTGIIKSIAPTSVNLNLTEIT  180

Query  206  HVEKLCTGTAPFTVAFGNS  224
            HV++LC+GT+ F+VAFGNS
Sbjct  181  HVQNLCAGTGTFSVAFGNS  199

5) tcpA in NC_016445


> AF208385|1|G1|7637504|AAF65209.1|Vibrio_cholerae_SCE188|+|1..600|tcpA|-|toxin 
coregulated pili subunit
Length=199

 Score =  249 bits (928),  Expect = 9e-68, Method: Compositional matrix adjust.
 Identities = 153/199 (77%), Positives = 186/199 (94%), Gaps = 0/199 (0%)

Query  26   MTLLEVIIVLGIMGVVSAGVVTLAQRAIDSQNMTKAAQNLNSVQIAMTQTYRSLGNYPat  85
            MTLLEVII LGIMGVVSAGVVTLAQRAIDSQNMTKAAQNLN++Q+++TQTYRSLGNYP+T
Sbjct  1    MTLLEVIIDLGIMGVVSAGVVTLAQRAIDSQNMTKAAQNLNTIQVSLTQTYRSLGNYPTT  60

Query  86   anasaatqlanGLVSLGKVSADEAKNPFTGTAMGIFSFPRNSAANKAFAITVGGLTQAQC  145
            A+A+AA+ L+ GLVSLGK+S+DEAKNPFTG+ + I SFPRN+A+NKAFAI+V+GLTQAQC
Sbjct  61   ADANAAAALTAGLVSLGKISSDEAKNPFTGSNLNIWSFPRNGAGNKAFAISVDGLTQAQC  120

Query  146  KTLVTSVGDMFPFINVKEGAFAAVADLGDFETSVADAATGAGVIKSIAPGSANLNLTNIT  205
            KTLVTSVGDMFP+INV++ A  ++ADLGDFET+VA A+TG+G+IKSIAP S NLNLT+IT
Sbjct  121  KTLVTSVGDMFPYINVQQKASMPLADLGDFETGVAAAGTGTGIIKSIAPTSVNLNLTEIT  180

Query  206  HVEKLCTGTAPFTVAFGNS  224
            HV++LC+GT+ F+VAFGNS
Sbjct  181  HVQNLCAGTGTFSVAFGNS  199

6) tcpA in NC_012582


> AF208385|1|G1|7637504|AAF65209.1|Vibrio_cholerae_SCE188|+|1..600|tcpA|-|toxin 
coregulated pili subunit
Length=199

 Score =  239 bits (892),  Expect = 7e-65, Method: Compositional matrix adjust.
 Identities = 157/199 (79%), Positives = 184/199 (93%), Gaps = 0/199 (0%)

Query  26   MTLLEVIIVLGIMGVVSAGVVTLAQRAIDSQNMTKAAQSLNSIQVALTQTYRGLGNYPAT  85
            MTLLEVII LGIMGVVSAGVVTLAQRAIDSQNMTKAAQ+LN+IQV+LTQTYR+LGNYP+T
Sbjct  1    MTLLEVIIDLGIMGVVSAGVVTLAQRAIDSQNMTKAAQNLNTIQVSLTQTYRSLGNYPTT  60

Query  86   ADATAASKLTSGLVSLGKISSDEAKNPFIGTNMNIFSFPRNAAANKAFAISVDGLTQAQC  145
            ADA AA+ LT+GLVSLGKISSDEAKNPF G+N+NI SFPRN+A+NKAFAISVDGLTQAQC
Sbjct  61   ADANAAAALTAGLVSLGKISSDEAKNPFTGSNLNIWSFPRNGAGNKAFAISVDGLTQAQC  120

Query  146  KTLITSVGDMFPYIAIKaggavaladlgdFENSAAAAETGVGVIKSIAPASKNLDLTNIT  205
            KTL+TSVGDMFPYI ++  ++++LADLGDFE + AAA TG G+IKSIAP+S NL+LT+IT
Sbjct  121  KTLVTSVGDMFPYINVQQKASMPLADLGDFETGVAAAGTGTGIIKSIAPTSVNLNLTEIT  180

Query  206  HVEKLCKGTAPFGVAFGNS  224
            HV++LC GT+ F+VAFGNS
Sbjct  181  HVQNLCAGTGTFSVAFGNS  199

7) tcpA in NC_009457


> AF208385|1|G1|7637504|AAF65209.1|Vibrio_cholerae_SCE188|+|1..600|tcpA|-|toxin 
coregulated pili subunit
Length=199

 Score =  239 bits (892),  Expect = 7e-65, Method: Compositional matrix adjust.
 Identities = 157/199 (79%), Positives = 184/199 (93%), Gaps = 0/199 (0%)

Query  26   MTLLEVIIVLGIMGVVSAGVVTLAQRAIDSQNMTKAAQSLNSIQVALTQTYRGLGNYPAT  85
            MTLLEVII LGIMGVVSAGVVTLAQRAIDSQNMTKAAQ+LN+IQV+LTQTYR+LGNYP+T
Sbjct  1    MTLLEVIIDLGIMGVVSAGVVTLAQRAIDSQNMTKAAQNLNTIQVSLTQTYRSLGNYPTT  60

Query  86   ADATAASKLTSGLVSLGKISSDEAKNPFIGTNMNIFSFPRNAAANKAFAISVDGLTQAQC  145
            ADA AA+ LT+GLVSLGKISSDEAKNPF G+N+NI SFPRN+A+NKAFAISVDGLTQAQC
Sbjct  61   ADANAAAALTAGLVSLGKISSDEAKNPFTGSNLNIWSFPRNGAGNKAFAISVDGLTQAQC  120

Query  146  KTLITSVGDMFPYIAIKaggavaladlgdFENSAAAAETGVGVIKSIAPASKNLDLTNIT  205
            KTL+TSVGDMFPYI ++  ++++LADLGDFE + AAA TG G+IKSIAP+S NL+LT+IT
Sbjct  121  KTLVTSVGDMFPYINVQQKASMPLADLGDFETGVAAAGTGTGIIKSIAPTSVNLNLTEIT  180

Query  206  HVEKLCKGTAPFGVAFGNS  224
            HV++LC GT+ F+VAFGNS
Sbjct  181  HVQNLCAGTGTFSVAFGNS  199

8) tcpA in NC_006841


> AF208385|1|G1|7637504|AAF65209.1|Vibrio_cholerae_SCE188|+|1..600|tcpA|-|toxin 
coregulated pili subunit
Length=199

 Score =  142 bits (524),  Expect = 8e-36, Method: Compositional matrix adjust.
 Identities = 89/192 (47%), Positives = 139/192 (73%), Gaps = 5/192 (2%)

Query  9    MTLLEVIIVLGIMGVISAGVVILAQRAIDNQNVSKLSQALNTIQTAMVQTYRSKQSYPDV  68
            MTLLEVII LGIMGV+SAGVV LAQRAID+QN++K +Q LNTIQ ++ QTYRS  +YP  
Sbjct  1    MTLLEVIIDLGIMGVVSAGVVTLAQRAIDSQNMTKAAQNLNTIQVSLTQTYRSLGNYPTT  60

Query  69   LQDAVKAKKLTDALVSMGRVTESDLINPFTGAPMLIFTAKDNKAANRGFAIKVSDLSKDQ  128
              DA  A  LT +LVS+G+++  +  NPFTG+ + I +   N A+N++FAI V +L++ Q
Sbjct  61   -ADANAAAALTAGLVSLGKISSDEAKNPFTGSNLNIWSFPRNGAGNKAFAISVDGLTQAQ  119

Query  129  CTSLISNSADLFSFIEVQNRGT-AMA--ADFYVD-PDATKSVGVIKSTKGGAKTLDLTNL  184
            C +L+++ +D+F++I+VQ++++ ++A  +DF  + + A  + G+IKS    +  L+LT++
Sbjct  120  CKTLVTSVGDMFPYINVQQKASMPLADLGDFETGVAAAGTGTGIIKSIAPTSVNLNLTEI  179

Query  185  DHISALCGGPGA  196
             H+  LC+G G+
Sbjct  180  THVQNLCAGTGT  191