PAI Gene Information


Name : vat (APECO1_1712)
Accession : YP_851472.1
PAI name : PAI III APEC-O1
PAI accession : NC_008563_P2
Strain : Escherichia coli 042
Virulence or Resistance: Not determined
Product : vacuolating autotransporter
Function : -
Note : hemoglobin protease
Homologs in the searched genomes :   39 hits    ( 37 protein-level,   2 DNA-level )  
Publication :
    -Johnson,T.J. and Nolan,L.K., "Direct Submission", Submitted (14-SEP-2006) Veterinary Microbiology and Preventive Medicine, Iowa State University, 1802 Elwood Drive, VMRI 2, Ames, IA 50011, USA.

    -Johnson,T.J., Kariyawasam,S., Wannemuehler,Y., Mangiamele,P., Johnson,S.J., Doetkott,C., Skyberg,J.A., Lynne,A.M., Johnson,J.R. and Nolan,L.K., "The genome sequence of avian pathogenic Escherichia coli strain O1:K1:H7 shares strong similarities with human extraintestinal pathogenic E. coli genomes", J. Bacteriol. 189 (8), 3228-3236 (2007) PUBMED 17293413 REMARK Erratum:[J Bacteriol. 2007 Jun;189(12):4554].

    -Johnson,T.J., Kariyawasam,S., Wannemuehler,Y., Mangiamele,P., Johnson,S.J., Doetkott,C., Skyberg,J.A., Lynne,A.M., Johnson,J.R. and Nolan,L.K., "Direct Submission", Submitted (08-NOV-2006) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA.


DNA sequence :
ATGAATAAAATATACGCTCTAAAATATTGTTATATTACTAACACAGTAAAGGTTGTCTCTGAACTAGCCCGAAGGGTATG
TAAAGGGAGTACCCGCAGAGGAAAAAGACTTTCAGTACTTACCTCTCTGGCACTATCTGCATTACTCCCAACCGTTGCTG
GTGCATCAACGGTTGGTGGCAACAATCCTTACCAGACATACCGCGACTTTGCAGAAAACAAAGGGCAGTTTCAGGCTGGC
GCAACAAACATTCCTATTTTTAATAATAAAGGGGAATTAGTAGGACATCTTGATAAAGCGCCCATGGTTGATTTTAGCAG
TGTGAATGTAAGCTCAAATCCCGGCGTTGCAACATTAATTAACCCGCAATATATAGCCAGTGTAAAACATAATAAAGGAT
ATCAGAGCGTCAGCTTCGGTGATGGTCAGAACAGTTACCATATTGTGGATCGTAATGAACACAGTTCATCTGATCTCCAC
ACACCAAGACTTGATAAGCTCGTAACTGAGGTTGCTCCGGCTACCGTAACCAGCTCATCAACAGCTGATATATTGAACCC
TTCAAAATACTCGGCATTCTACAGGGCTGGTTCGGGAAGTCAGTATATTCAGGATAGTCAGGGTAAGCGACATTGGGTAA
CAGGTGGGTATGGTTATCTGACAGGAGGAATACTCCCGACATCATTCTTTTATCACGGCTCAGACGGCATTCAGCTGTAT
ATGGGGGGCAACATACATGATCATAGCATCCTGCCCTCTTTTGGAGAGGCCGGCGACAGTGGTTCTCCATTATTTGGCTG
GAATACGGCCAAAGGGCAGTGGGAACTGGTCGGTGTTTACTCGGGAGTAGGAGGGGGGACCAATTTGATATATTCTCTTA
TTCCTCAGAGTTTTCTCTCACAGATCTATTCAGAGGATAATGACGCTCCCGTCTTTTTTAATGCCTCATCCGGCGCCCCC
CTGCAATGGAAATTTGACAGCAGCACCGGCACTGGCTCTCTGAAACAGGGTTCCGATGAATATGCCATGCACGGGCAAAA
AGGTTCTGACCTGAACGCAGGTAAAAATCTGACATTCCTGGGACATAATGGTCAGATTGACCTGGAAAACTCTGTCACGC
AGGGTGCCGGTTCACTGACATTTACTGATGACTACACTGTCACCACTTCAAACGGAAGTACCTGGACCGGGGCCGGTATT
ATTGTGGACAAGGATGCCTCCGTAAACTGGCAGGTTAATGGTGTGAAAGGTGACAACCTGCATAAAATCGGCGAAGGAAC
CCTGGTTGTACAGGGAACCGGTGTTAATGAGGGCGGCCTGAAAGTCGGGGATGGGACCGTTGTCCTCAATCAGCAGGCTG
ACAGTTCAGGACACGTTCAGGCATTCAGTAGCGTGAATATTGCCAGCGGCCGCCCGACAGTCGTGCTGGCAGACAACCAG
CAGGTTAATCCGGACAATATATCCTGGGGCTACCGGGGGGGGGTTCTGGATGTTAACGGGAATGACCTGACATTTCATAA
GCTGAATGCCGCCGATTATGGCGCAACTCTCGGTAACAGCAGTGATAAAACGGCTAATATCACTCTGGATTATCAGACGC
GTCCGGCAAACGTAAAAGTTAATGAATGGTCATCATCAAACAGGGGAACAGTAGGTTCATTATATATTTATAATAATCCC
TATACTCATACCGTCGATTATTTTATCCTGAAAACAAGTAGTTATGGCTGGTTCCCTACCGGTCAGGTCAGTAACGAGCA
CTGGGAATATGTCGGACATGACCAGAACAGTGCACAGGCGCTGCTTGCAAACAGAATTAATAATAAAGGGTATCTGTATC
ATGGCAAGTTGCTGGGAAATATTAATTTCTCAAATAAAGCAACCCCGGGTACAACCGGCGCATTGGTTATGGACGGCTCA
GCGAATATGTCCGGTACATTTACTCAGGAAAACGGTCGTCTGACCATTCAGGGCCACCCGGTTATCCATGCTTCAACGTC
TCAGAGTATTGCAAATACAGTCTCGTCTCTGGGCGACAATTCCGTTCTGACACAGCCCACCTCATTTACACAGGATGACT
GGGAGAACAGGACGTTCAGCTTTGGTTCGCTCGTGTTAAAAGATACAGACTTTGGTCTGGGCCGCAATGCCACACTGAAC
ACAACCATCCAGGCAGATAACTCCAGCGTCACGCTGGGCGACAGTCGGGTATTTATCGACAAAAAAGATGGCCAGGGAAC
AGCATTTACCCTTGAAGAAGGCACATCTGTTGCAACTAAAGATGCAGATAAAAGCGTCTTCAACGGCACCGTCAACCTGG
ATAATCAGTCAGTGCTGAATATCAATGAGATATTCAATGGCGGAATACAGGCGAACAACAGTACCGTGAATATCTCCTCA
GACAGTGCCGTTCTGGAGAACTCAACGCTGACCAGTACCGCCCTGAATCTGAACAAGGGAGCAAATGTTCTGGCCAGTCA
GAGTTTTGTTTCTGACGGTCCGGTGAATATTTCTGATGCCACCCTGAGTCTGAACAGCCGTCCTGATGAGGTATCTCACA
CACTTTTACCTGTATACGATTATGCCGGTTCATGGAACCTGAAGGGAGACGATGCCCGCCTGAACGTGGGGCCGTACAGT
ATGTTGTCAGGTAATATCAATGTTCAGGATAAAGGGACTGTCACCCTCGGAGGGGAAGGGGAACTGAGTCCTGACCTGAC
TCTTCAGAATCAGATGTTGTACAGCCTGTTTAACGGGTACCGCAATACCTGGAGCGGGAGCCTGAATGCACCGGATGCCA
CCGTCAGCATGACAGACACCCAGTGGTCGATGAACGGAAACTCCACGGCAGGAAATATGAAACTTAACCGGACAATAGTC
GGTTTTAACGGGGGAACATCATCGTTCACGACACTGACAACAGATAATCTGGACGCGGTTCAGTCAGCATTTGTCATGCG
TACAGACCTTAACAAGGCAGACAAACTGGTGATAAACAAGTCGGCAACAGGTCATGACAACAGCATCTGGGTTAACTTCC
TGAAAAAACCCTCTGACAAGGACACGCTTGATATTCCACTGGTCAGCGCACCTGAAGCGACAGCTGATAATCTGTTCAGG
GCATCAACACGGGTTGTGGGATTCAGTGATGTCACCCCCACCCTTAGTGTCAGAAAAGAGGACGGGAAAAAAGAGTGGGT
CCTCGATGGTTACCAGGTTGCACGTAACGACGGCCAGGGTAAGGCTGCCGCCACATTCATGCACATCAGCTATAACAACT
TCATCACTGAAGTTAACAACCTGAACAAACGCATGGGCGATTTGAGGGATATTAACGGCGAAGCCGGTACGTGGGTGCGT
CTGCTGAACGGTTCCGGCTCTGCTGATGGCGGTTTCACTGACCACTATACCCTGCTGCAGATGGGGGCTGACCGTAAGCA
CGAACTGGGAAGTATGGACCTGTTTACCGGCGTGATGGCCACCTACACTGACACAGATGCGTCAGCAGGCCTGTACAGCG
GTAAAACAAAATCATGGGGTGGTGGTTTCTATGCCAGTGGTCTGTTCCGGTCCGGCGCTTACTTTGATTTGATTGCCAAA
TATATTCACAATGAAAACAAATATGACCTGAACTTTGCCGGAGCTGGTAAACAGAACTTCCGCAGCCATTCACTGTATGC
AGGTGCAGAAGTCGGATACCGTTATCATCTGACAGATACGACGTTTGTTGAACCTCAGGCGGAACTGGTCTGGGGAAGAC
TGCAGGGCCAAACATTTAACTGGAACGACAGTGGAATGGATGTCTCAATGCGTCGTAACAGCGTTAATCCTCTGGTAGGC
AGAACCGGCGTTGTTTCCGGTAAAACCTTCAGTGGTAAGGACTGGAGTCTGACAGCCCGTGCCGGCCTGCATTATGAGTT
CGATCTGACGGACAGTGCTGACGTTCACCTGAAGGATGCAGCGGGAGAACATCAGATTAATGGCAGAAAAGACGGTCGTA
TGCTTTACGGTGTGGGGTTAAATGCCCGGTTTGGCGACAATACGCGTCTGGGGCTGGAAGTTGAACGCTCTGCATTCGGT
AAATACAACACAGATGATGCGATAAACGCTAATATTCGTTATTCATTCTGA

Protein sequence :
MNKIYALKYCYITNTVKVVSELARRVCKGSTRRGKRLSVLTSLALSALLPTVAGASTVGGNNPYQTYRDFAENKGQFQAG
ATNIPIFNNKGELVGHLDKAPMVDFSSVNVSSNPGVATLINPQYIASVKHNKGYQSVSFGDGQNSYHIVDRNEHSSSDLH
TPRLDKLVTEVAPATVTSSSTADILNPSKYSAFYRAGSGSQYIQDSQGKRHWVTGGYGYLTGGILPTSFFYHGSDGIQLY
MGGNIHDHSILPSFGEAGDSGSPLFGWNTAKGQWELVGVYSGVGGGTNLIYSLIPQSFLSQIYSEDNDAPVFFNASSGAP
LQWKFDSSTGTGSLKQGSDEYAMHGQKGSDLNAGKNLTFLGHNGQIDLENSVTQGAGSLTFTDDYTVTTSNGSTWTGAGI
IVDKDASVNWQVNGVKGDNLHKIGEGTLVVQGTGVNEGGLKVGDGTVVLNQQADSSGHVQAFSSVNIASGRPTVVLADNQ
QVNPDNISWGYRGGVLDVNGNDLTFHKLNAADYGATLGNSSDKTANITLDYQTRPANVKVNEWSSSNRGTVGSLYIYNNP
YTHTVDYFILKTSSYGWFPTGQVSNEHWEYVGHDQNSAQALLANRINNKGYLYHGKLLGNINFSNKATPGTTGALVMDGS
ANMSGTFTQENGRLTIQGHPVIHASTSQSIANTVSSLGDNSVLTQPTSFTQDDWENRTFSFGSLVLKDTDFGLGRNATLN
TTIQADNSSVTLGDSRVFIDKKDGQGTAFTLEEGTSVATKDADKSVFNGTVNLDNQSVLNINEIFNGGIQANNSTVNISS
DSAVLENSTLTSTALNLNKGANVLASQSFVSDGPVNISDATLSLNSRPDEVSHTLLPVYDYAGSWNLKGDDARLNVGPYS
MLSGNINVQDKGTVTLGGEGELSPDLTLQNQMLYSLFNGYRNTWSGSLNAPDATVSMTDTQWSMNGNSTAGNMKLNRTIV
GFNGGTSSFTTLTTDNLDAVQSAFVMRTDLNKADKLVINKSATGHDNSIWVNFLKKPSDKDTLDIPLVSAPEATADNLFR
ASTRVVGFSDVTPTLSVRKEDGKKEWVLDGYQVARNDGQGKAAATFMHISYNNFITEVNNLNKRMGDLRDINGEAGTWVR
LLNGSGSADGGFTDHYTLLQMGADRKHELGSMDLFTGVMATYTDTDASAGLYSGKTKSWGGGFYASGLFRSGAYFDLIAK
YIHNENKYDLNFAGAGKQNFRSHSLYAGAEVGYRYHLTDTTFVEPQAELVWGRLQGQTFNWNDSGMDVSMRRNSVNPLVG
RTGVVSGKTFSGKDWSLTARAGLHYEFDLTDSADVHLKDAAGEHQINGRKDGRMLYGVGLNARFGDNTRLGLEVERSAFG
KYNTDDAINANIRYSF