PAI Gene Information


Name : epiB (SAUSA300_1766)
Accession : YP_494457.1
PAI name : vSa_beta
PAI accession : NC_007793_P5
Strain : Staphylococcus aureus 04-02981
Virulence or Resistance: Resistance
Product : lantibiotic epidermin biosynthesis protein EpiB
Function : -
Note : identified by match to protein family HMM PF04737; match to protein family HMM PF04738
Homologs in the searched genomes :   13 hits    ( 13 protein-level )  
Publication :
    -Diep,B.A., Gill,S.R., Chang,R.F., Phan,T.H., Chen,J.H., Davidson,M.G., Lin,F., Lin,J., Carleton,H.A., Mongodin,E.F., Sensabaugh,G.F. and Perdreau-Remington,F., "Complete genome sequence of USA300, an epidemic clone of community-acquired meticillin-resistant Staphylococcus aureus", Lancet 367 (9512), 731-739 (2006) PUBMED 16517273.

    -Diep,B.A., Gill,S.R., Chang,R.F., Phan,T.H., Chen,J.H., Davidson,M.G., Lin,F., Lin,J., Carleton,H.A., Mongodin,E.F., Sensabaugh,G.F. and Perdreau-Remington,F., "Direct Submission", Submitted (11-FEB-2006) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA.

    -Diep,B.A., Gill,S.R., Chang,R.F., Phan,T.H., Chen,J.H., Davidson,M.G., Lin,F., Lin,J., Carleton,H.A., Mongodin,E.F., Sensabaugh,G.F. and Perdreau-Remington,F., "Direct Submission", Submitted (30-JAN-2006) Department of Medicine, University of California, San Francisco, San Francisco, CA 94143, USA.


DNA sequence :
ATGAACACTATTTACGAACCGTCAAGTATTTGTATGATTAGAACACCTTTATTATCAGTTGAATTTTTCAATTTATTTTT
AAATACTGAACAAATTAAATATAGCGACTTACAATTAAATGCTCAGATGAAAGAATCAATCCTAACAACAACATTTAACT
TATATTGTACTTTACAAGAAATAAATTTTGATGGCGATAACAAGAAGGTTAGAGATGCTAAAGAAAGTTTATTAAAATAT
TTAATTAGAATGTCAACACGTCCAACTCCATTTGGATTATTAAGTGGTATTAATTTGGGGCATTTTGTAAATGAACCAAC
ACGTCTTAAAGTTGGAAATAGTATTCAAAAATATGTGAAAGTCGATGGCGAATGGTTGTATAAACTGGTTAGTTATATTG
AGAGTATTGATGAATATTATCAAAATTTGAAAGTTATTTGGAATAGTAAAGCACATATTATCAATGATCGAATATATTTA
AATGAACAAAGTGCTATTTATTTAAACAACAATAAAGATACATCTTTTTCCATTAAAAATAGCGAATTACTCGTATTCAT
CAAAACCACTGTGACGAATAATAATATTACTTTTTCAAATTTAGCTGAAAAGATAAATCAAGAATTTGAAATTAATGATA
TTACTAAAGTGAAAGTATATATCCATAATCTTGTCTCAAAGGAAATTATATATTCAACAATCAGACCACCGTTATCATAT
AGCGATAATTTAAATTATATTTTAAATAAACTTTCTTTACATAATGATGATTTTGTGAAAAAAATTAGAGAAATCCAGAA
ATTGATATTAGCTTATGAAAAAACTGAAATTGGATTTGGCGAGGAATTATATAAAGACATTATTCATCATATGAAGGCAC
TATTCAAATGTAAAAACTATCTTCAAATTGATACCAAAATTGACATGATTAACAATTATTTACATCAAGATATAGCAACA
AATATATCTGAAGCAGCGTACTTATTGTGGCTTTTATCAAGAAATAATATTGGATTCACAGATTTGAAAGTTCTTCACAA
CCGTTTTATTGAAAAGTATGGATTTGAACAACTCGTGAATATTAAAGATTTGATTTCAGATATAACAGGTTTCGGGACAA
CAATTTTTCAAGAAGAAGAAACCGATGGAAATAATATTGTAATGCTTAAGCAAAAATTTTTACATGCCTTGAGAAATAAC
GATGAGATAGTCATAAATGAAAAAGATGTAGAGTCATTGATTAACGATAATGAAATCAATCATTATCATGCGCCAATGAG
TGCAGATGTTTATGCTGAACTTTATTTAGGACGTTTTTACAATCAGTACAATGAGCTCATTGTTATTAGTCCTTTAACGG
CGTCTTTTAATGCTGGCGCTACATTTGGGCGATTTCATCATTTAATTGATACTGAAACTTTAGCAAAATTAGAACATGAA
AAAGGACATTATTATCAGAAGATGATATGTGATGACAATGTAGAAATGATTTCTATAAATAACATACCGAAATATCCGAG
AAATCATAATGTATTAACTAATCATGACTCATACGAATATTCATTGAATTTAGGAAGTAGTAATAGTTATTCAAAGTATG
AGCTTACCTTAGATGATATTTATGTTGGTGCTACCTTTAACAAATTATATTTATATTCTAGCCAACTAAATAAAAGGGTA
CTATTTGAATCAAACAATATGTATAACTTTTTAAAAGAATGTAATTTATATCGATTGTTACGAGAAATTTCAATGGAATC
TGTGAAATGCATTGAACCTATGAATGATGTGAGTATTGATTCATTTAGTTATTCACCACGAATCAGATATAAAAATGTCA
TTCTTAAACCAGCATATTGGAAAATTAACGAGATGGTATTACCTTTACCTAAAAATGAAGAATGGGATCAACAATTTTTG
AAATATCAAGAACAATTCAATATACCTAATATCGTGAATTTAGTTTATGGAGATAACAAGCTTCTACTAAATTTATCATT
AGCTAATCATAGATATTTATTGATGAAAGAATATAAGAAGCATAAACGTGTACGTTTAGTAGAATCATTTTTACCTCAAT
CAAAGAATGATCATGTGTATGAAATTGTTACACCAATTTATAAAAAATCATCTTATCGAGGACCCGAAATCGAAATTCCA
AAATATAAAAATACAGATATTGAATATGACAAAGACTGGTTTGCATTACATATTCATATCGATAAGCCATCGCAAGATAC
ATTTATCATCGACAATTTGTATCCATTTGTAAAACATCTTAAAGATAAGGGAGATATAGATCAATATTTTTTAATGCGTT
ATATCAAACAAGGTGACATTTTAAAGTTGAGGTTATTCAGGAATGACGAAAATTACGCAGAAATATACAGCATCTTGAAG
AATTGGTTACCACATGTTCGACAAACGACAGAAGTTTCAGATTATGAATTTGTATCATACGAGCCAGAATTTTTTAGATA
TGGTGGAAAGAACACGATTAATGAAATAGAAGCCTTCTTTGAATATGACACGAATTTAGCTGTCAATATTATTGAAAATG
ATTTTAAGTTTGATCGACCATATATTGTTGCTATTTCAATAATGTATTTATTTGAGATGTTTTCAATTTCTAATGAAGAG
CGTATGGAAATTGTTAATAACTATGTACCTACATCATTTAAAAGTAAAGATATTAGACCTTTTAAAAATGAACTTGTAAC
TATATGTAATCCTGCTAATAATTTTGAATATATGGCTAAACACTATAGTGGTATTTATCGAATTTTAAAAGATGGCAACC
AAATTTTGAGCAAATTAAATGAAGGGCTTAAAAAAACTTTAACTACTAAAAGGTCAAGGATTATTGGCAGCTTAATTCAT
ATGCGCTGCAATCGAATATTTGGCATTGATAAGGATCAAGAAACATTTGTTTTATCTATTGTAAAAGAAATTGTTAAAAC
TCAAAAGCATTGGTGTGGTGACAAAAATGATTGA

Protein sequence :
MNTIYEPSSICMIRTPLLSVEFFNLFLNTEQIKYSDLQLNAQMKESILTTTFNLYCTLQEINFDGDNKKVRDAKESLLKY
LIRMSTRPTPFGLLSGINLGHFVNEPTRLKVGNSIQKYVKVDGEWLYKLVSYIESIDEYYQNLKVIWNSKAHIINDRIYL
NEQSAIYLNNNKDTSFSIKNSELLVFIKTTVTNNNITFSNLAEKINQEFEINDITKVKVYIHNLVSKEIIYSTIRPPLSY
SDNLNYILNKLSLHNDDFVKKIREIQKLILAYEKTEIGFGEELYKDIIHHMKALFKCKNYLQIDTKIDMINNYLHQDIAT
NISEAAYLLWLLSRNNIGFTDLKVLHNRFIEKYGFEQLVNIKDLISDITGFGTTIFQEEETDGNNIVMLKQKFLHALRNN
DEIVINEKDVESLINDNEINHYHAPMSADVYAELYLGRFYNQYNELIVISPLTASFNAGATFGRFHHLIDTETLAKLEHE
KGHYYQKMICDDNVEMISINNIPKYPRNHNVLTNHDSYEYSLNLGSSNSYSKYELTLDDIYVGATFNKLYLYSSQLNKRV
LFESNNMYNFLKECNLYRLLREISMESVKCIEPMNDVSIDSFSYSPRIRYKNVILKPAYWKINEMVLPLPKNEEWDQQFL
KYQEQFNIPNIVNLVYGDNKLLLNLSLANHRYLLMKEYKKHKRVRLVESFLPQSKNDHVYEIVTPIYKKSSYRGPEIEIP
KYKNTDIEYDKDWFALHIHIDKPSQDTFIIDNLYPFVKHLKDKGDIDQYFLMRYIKQGDILKLRLFRNDENYAEIYSILK
NWLPHVRQTTEVSDYEFVSYEPEFFRYGGKNTINEIEAFFEYDTNLAVNIIENDFKFDRPYIVAISIMYLFEMFSISNEE
RMEIVNNYVPTSFKSKDIRPFKNELVTICNPANNFEYMAKHYSGIYRILKDGNQILSKLNEGLKKTLTTKRSRIIGSLIH
MRCNRIFGIDKDQETFVLSIVKEIVKTQKHWCGDKND