PAI Gene Information


Name : SAUSA300_1053 (SAUSA300_1053)
Accession : YP_493751.1
PAI name : vSa_gamma
PAI accession : NC_007793_P3
Strain : Staphylococcus aureus 04-02981
Virulence or Resistance: Not determined
Product : formyl peptide receptor-like 1 inhibitory protein
Function : -
Note : FLIPr; secreted protein that blocks the formyl peptide receptor-like 1 (FPRL1) found in neutrophils, monocytes, B cells, and NK cells; inhibits the binding of chemoattractants (such as formylated peptides) to FPRL1, which initiates the phagocyte mobilizat
Homologs in the searched genomes :   38 hits    ( 37 protein-level,   1 DNA-level )  
Publication :
    -Diep,B.A., Gill,S.R., Chang,R.F., Phan,T.H., Chen,J.H., Davidson,M.G., Lin,F., Lin,J., Carleton,H.A., Mongodin,E.F., Sensabaugh,G.F. and Perdreau-Remington,F., "Complete genome sequence of USA300, an epidemic clone of community-acquired meticillin-resistant Staphylococcus aureus", Lancet 367 (9512), 731-739 (2006) PUBMED 16517273.

    -Diep,B.A., Gill,S.R., Chang,R.F., Phan,T.H., Chen,J.H., Davidson,M.G., Lin,F., Lin,J., Carleton,H.A., Mongodin,E.F., Sensabaugh,G.F. and Perdreau-Remington,F., "Direct Submission", Submitted (11-FEB-2006) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA.

    -Diep,B.A., Gill,S.R., Chang,R.F., Phan,T.H., Chen,J.H., Davidson,M.G., Lin,F., Lin,J., Carleton,H.A., Mongodin,E.F., Sensabaugh,G.F. and Perdreau-Remington,F., "Direct Submission", Submitted (30-JAN-2006) Department of Medicine, University of California, San Francisco, San Francisco, CA 94143, USA.


DNA sequence :
ATGAAAAAAAATATCACAAAAACTATTATCGCATCTACAGTAATCGCTGCAGGTCTTTTAACTCAAACTAATGATGCTAA
AGCTTTCTTTAGTTATGAATGGAAAGGTTTAGAAATCGCAAAAAATTTAGCAGATCAAGCTAAAAAGGACGATGAACGTA
TTGATAAGTTAATGAAAGAGTCTGATAAAAATCTAACTCCTTACAAAGCTGAAACTGTTAATGATCTGTACCTTATTGTT
AAAAAATTAAGCCAAGGTGATGTGAAGAAAGCAGTTGTCAGAATTAAAGATGGTGGTCCTAGAGATTACTATACTTTTGA
CTTAACTCGTCCTTTAGAAGAGAACAGAAAAAATATTAAAGTTGTTAAAAACGGTGAAATCGACTCGATTACTTGGTATT
AA

Protein sequence :
MKKNITKTIIASTVIAAGLLTQTNDAKAFFSYEWKGLEIAKNLADQAKKDDERIDKLMKESDKNLTPYKAETVNDLYLIV
KKLSQGDVKKAVVRIKDGGPRDYYTFDLTRPLEENRKNIKVVKNGEIDSITWY