Name : nadC (M5005_Spy_0170)
Accession : YP_281534.1
PAI name : Not named
PAI accession : NC_007297_P1
Strain : Streptococcus pyogenes A20
Virulence or Resistance: Not determined
Product : nicotinate-nucleotide pyrophosphorylase
Function : -
Note : catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide
Homologs in the searched genomes : 854 hits ( 854 protein-level )
Publication :
-Porcella,S.F., "Direct Submission", Submitted (20-AUG-2004) Laboratory of Human Bacterial Pathogenesis, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Disease, National Institutes of Health, 903 S. 4th Street, Hamilton, MT 59840, USA.
-Sumby,P., Porcella,S.F., Madrigal,A.G., Barbian,K.D., Virtaneva,K., Ricklefs,S.M., Sturdevant,D.E., Graham,M.R., Vuopio-Varkila,J., Hoe,N.P. and Musser,J.M., "Evolutionary origin and emergence of a highly successful clone of serotype M1 group a Streptococcus involved multiple horizontal gene transfer events", J. Infect. Dis. 192 (5), 771-782 (2005) PUBMED 16088826.
-Sumby,P., Porcella,S.F., Madrigal,A.G., Barbian,K.D., Virtaneva,K., Ricklefs,S.M., Sturdevant,D.E., Graham,M.R., Vuopio-Varkila,J., Hoe,N.P. and Musser,J.M., "Direct Submission", Submitted (08-AUG-2005) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA.
DNA sequence : | |
ATGTCAATCATTTCAACTGATTTAACCCCTTTTCAAATAGATGATACATTGAAAGCAGCCTTGCGAGAAGATGTTCATTC
CGAAGATTACAGTACCAATGCCATTTTTGATCATCATGGCCAAGCCAAGGTGTCGCTTTTTGCCAAGGAAGCTGGTGTTT
TAGCGGGGCTAACCGTTTTTCAAAGGGTTTTTACCCTATTTGATGCCGAGGTGACCTTCCAGAATCCTCATCAATTTAAG
GATGGGGATCGTTTGACTAGTGGCGATTTGGTTTTAGAAATCATAGGCTCGGTGAGAAGCCTCTTAACATGTGAACGCGT
TGCCTTGAATTTTTTACAACATTTATCAGGGATTGCTTCGATGACAGCTGCTTATGTAGAAGCCTTAGGCGATGATCGCA
TTAAGGTATTTGATACTCGAAAAACCACTCCTAATTTACGTCTTTTTGAGAAATATGCCGTGAGAGTTGGCGGTGGCTAT
AATCATCGCTTTAATTTATCAGATGCTATCATGCTAAAAGACAATCACATTGCGGCAGTAGGTAGTGTTCAAAAGGCGAT
TGCTCAAGCGCGTGCCTATGCCCCTTTTGTGAAAATGGTCGAGGTGGAAGTGGAAAGCCTTGCTGCTGCCGAAGAAGCTG
CGGCGGCGGGTGTTGATATTATCATGTTGGATAATATGTCATTGGAACAGATTGAACAGGCCATTACTCTAATTGCAGGA
CGTTCTCGGATTGAATGTTCTGGAAATATTGATATGACCACTATTAGCCGTTTTCGTGGTTTAGCGATTGATTACGTCTC
CAGTGGTAGTTTAACCCATAGTGCTAAGAGTCTCGATTTTTCCATGAAGGGTTTAACCTACCTTGATGTCTAA
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Protein sequence : | |
MSIISTDLTPFQIDDTLKAALREDVHSEDYSTNAIFDHHGQAKVSLFAKEAGVLAGLTVFQRVFTLFDAEVTFQNPHQFK
DGDRLTSGDLVLEIIGSVRSLLTCERVALNFLQHLSGIASMTAAYVEALGDDRIKVFDTRKTTPNLRLFEKYAVRVGGGY
NHRFNLSDAIMLKDNHIAAVGSVQKAIAQARAYAPFVKMVEVEVESLAAAEEAAAAGVDIIMLDNMSLEQIEQAITLIAG
RSRIECSGNIDMTTISRFRGLAIDYVSSGSLTHSAKSLDFSMKGLTYLDV
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