Name : thyA (SERP1582)
Accession : YP_189147.1
PAI name : phi_SP_beta
PAI accession : NC_002976_P2
Strain : Staphylococcus epidermidis ATCC 12228
Virulence or Resistance: Not determined
Product : thymidylate synthase
Function : -
Note : ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived
Homologs in the searched genomes : 425 hits ( 425 protein-level )
Publication :
-Gill,S.R., "Direct Submission", Submitted (20-OCT-2004) The Institute for Genomic Research, 9712 Medical Center Dr, Rockville, MD 20850, USA.
-Gill,S.R., "Direct Submission", Submitted (08-APR-2002) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA.
-Gill,S.R., Fouts,D.E., Archer,G.L., Mongodin,E.F., Deboy,R.T., Ravel,J., Paulsen,I.T., Kolonay,J.F., Brinkac,L., Beanan,M., Dodson,R.J., Daugherty,S.C., Madupu,R., Angiuoli,S.V., Durkin,A.S., Haft,D.H., Vamathevan,J., Khouri,H., Utterback,T., Lee,C., Dimi, "Insights on evolution of virulence and resistance from the complete genome analysis of an early methicillin-resistant Staphylococcus aureus strain and a biofilm-producing methicillin-resistant Staphylococcus epidermidis strain", J. Bacteriol. 187 (7), 2426-2438 (2005) PUBMED 15774886.
| DNA sequence : | |
ATGTATAATCCATTCGACGAAGCTTATCATGGCTTATGCGAAGAGATATTAGAAATAGGGAATAGACGCGATGATCGCAC
ACATACCGGGACAATTTCCAAATTTGGGCATCAATTGCGTTTCGATTTAACCAAAGGGTTTCCTTTACTTACAACCAAAA
AGGTTTCTTTTAAATTAGTAGCAACTGAATTATTATGGTTTATTAAAGGAGATACAAACATTCAATACCTACTTAAATAT
AATAACAATATATGGAATGAATGGGCATTTGAAAATTATGTTCAGTCTGATGATTATCATGGACCAGACATGACAGATTT
TGGACATCGTTCCCAGCAAGACCCTGAATTTAACGAGCAGTATAAAGAAGAAATGAAAAAATTTAAAGAACGTATTCTAA
ACGATGATGCATTTGCTAAAAAATATGGCAACTTAGGGAATGTTTATGGTAAACAATGGAGAGATTGGGAAGATAAAAAT
GGAAATCATTACGATCAATTAAAATCAGTTATACAACAAATTAAAACCAATCCAAACTCTCGACGTCACATTGTTTCAGC
ATGGAATCCTACTGAAATCGATTCAATGGCATTACCACCTTGCCACACAATGTTTCAATTTTACGTACAAGAGGGTAAAT
TAAATTGTCAATTATATCAAAGAAGTGCTGATATATTTTTAGGTGTTCCTTTCAATATTGCAAGTTATGCTTTACTGACA
CATCTTGTTGCAAAAGAATGTGGACTTGAGGTGGGTGAATTCATTCATACATTTGGAGATGCACATATTTATTCCAATCA
TATGGATGCAATACATACACAATTATCAAGAGATAGTTATCTACCACCTCAATTAAAAATTAATACAGATAAATCAATTT
TTGATATTAATTATGAAGATTTAGAATTGATAAATTATGAATCACACCCTGCTATTAAAGCACCTATTGCGGTATAA
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| Protein sequence : | |
MYNPFDEAYHGLCEEILEIGNRRDDRTHTGTISKFGHQLRFDLTKGFPLLTTKKVSFKLVATELLWFIKGDTNIQYLLKY
NNNIWNEWAFENYVQSDDYHGPDMTDFGHRSQQDPEFNEQYKEEMKKFKERILNDDAFAKKYGNLGNVYGKQWRDWEDKN
GNHYDQLKSVIQQIKTNPNSRRHIVSAWNPTEIDSMALPPCHTMFQFYVQEGKLNCQLYQRSADIFLGVPFNIASYALLT
HLVAKECGLEVGEFIHTFGDAHIYSNHMDAIHTQLSRDSYLPPQLKINTDKSIFDINYEDLELINYESHPAIKAPIAV
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