Name : splA (SACOL1869)
Accession : YP_186697.1
PAI name : vSa_beta
PAI accession : NC_002951_P4
Strain : Staphylococcus aureus 04-02981
Virulence or Resistance: Virulence
Product : serine protease SplA
Function : -
Note : identified by similarity to GP:9739156; match to protein family HMM PF00089
Homologs in the searched genomes : 184 hits ( 182 protein-level, 2 DNA-level )
Publication :
-Gill,S.R., Fouts,D.E., Archer,G.L., Mongodin,E.F., Deboy,R.T., Ravel,J., Paulsen,I.T., Kolonay,J.F., Brinkac,L., Beanan,M., Dodson,R.J., Daugherty,S.C., Madupu,R., Angiuoli,S.V., Durkin,A.S., Haft,D.H., Vamathevan,J., Khouri,H., Utterback,T., Lee,C., Dimi, "Insights on evolution of virulence and resistance from the complete genome analysis of an early methicillin-resistant Staphylococcus aureus strain and a biofilm-producing methicillin-resistant Staphylococcus epidermidis strain", J. Bacteriol. 187 (7), 2426-2438 (2005) PUBMED 15774886.
-Gill,S.R., Fouts,D.E., Archer,G.L., Mongodin,E.F., DeBoy,R.T., Ravel,J., Paulsen,I.T., Kolonay,J.F., Dodson,R.J., Durkin,A.S., Brinkac,L., Beanan,M., Daugherty,S.C., Madupu,R., Angiuoli,S.V., Haft,D.H., Vamathevan,J., Khouri,H., Utterback,T., Lee,C., Dimi, "Direct Submission", Submitted (12-NOV-2004) The Institute for Genomic Research, 9712 Medical Center Dr, Rockville, MD 20850, USA.
-Gill,S.R., Fouts,D.E., Archer,G.L., Mongodin,E.F., DeBoy,R.T., Ravel,J., Paulsen,I.T., Kolonay,J.F., Dodson,R.J., Durkin,A.S., Brinkac,L., Beanan,M., Daugherty,S.C., Madupu,R., Angiuoli,S.V., Haft,D.H., Vamathevan,J., Khouri,H., Utterback,T., Lee,C., Dimi, "Direct Submission", Submitted (08-APR-2002) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA.
DNA sequence : | |
ATGAATAAAAATGTAATGGTTAAAGGTTTAACTGCTTTAACTATTTTAACTATTTTAACATCTCTTGGTTTTGCTGAAAA
TATTTCTAATCAGCCTCATTCAATTGCCAAAGCAGAAAAGAATGTCAAAGAAATTACCGATGCAACTAAGGAACCATACA
ATTCAGTGGTAGCATTTGTGGGTGGTACTGGTGTAGTTGTTGGTAAAAATACAATCGTAACTAACAAACATATCGCTAAA
AGTAATGATATTTTTAAAAATAGAGTATCAGCACATCATTCGAGTAAAGGTAAAGGCGGAGGAAACTACGACGTTAAAGA
CATTGTAGAATATCCCGGAAAAGAAGACCTTGCGATAGTTCATGTTCATGAAACAAGTACAGAAGGTTTGAATTTTAATA
AGAACGTTAGTTATACAAAATTTGCAGACGGAGCAAAAGTGAAAGATAGAATTTCTGTTATTGGTTATCCAAAGGGTGCA
CAAACAAAATATAAAATGTTTGAATCGACAGGAACGATTAACCATATCAGTGGAACGTTTATGGAATTTGATGCGTATGC
ACAACCAGGTAATTCAGGATCTCCTGTATTGAATTCTAAACATGAACTGATTGGTATTTTATATGCAGGTAGTGGAAAAG
ATGAATCTGAAAAGAATTTCGGTGTTTATTTCACACCACAATTAAAAGAATTTATTCAAAATAATATTGAAAAATAA
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Protein sequence : | |
MNKNVMVKGLTALTILTILTSLGFAENISNQPHSIAKAEKNVKEITDATKEPYNSVVAFVGGTGVVVGKNTIVTNKHIAK
SNDIFKNRVSAHHSSKGKGGGNYDVKDIVEYPGKEDLAIVHVHETSTEGLNFNKNVSYTKFADGAKVKDRISVIGYPKGA
QTKYKMFESTGTINHISGTFMEFDAYAQPGNSGSPVLNSKHELIGILYAGSGKDESEKNFGVYFTPQLKEFIQNNIEK
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