PAI Gene Information


Name : SAR0450 (SAR0450)
Accession : YP_039898.1
PAI name : vSa_alpha
PAI accession : NC_002952_P2
Strain : Staphylococcus aureus 04-02981
Virulence or Resistance: Not determined
Product : cobalamin synthesis protein
Function : -
Note : Similar to Pseudomonas chlororaphis hypothetical protein, needed for nitrile hydratase expression SW:P47K_PSECL (P31521) (419 aa) fasta scores: E(): 1.2e-55, 43.142% id in 401 aa, and to Bacillus subtilis hypothetical protein YciC TR:P94400 (EMBL:D50453)
Homologs in the searched genomes :   632 hits    ( 632 protein-level )  
Publication :
    -Holden,M.T.G., "Direct Submission", Submitted (23-JUN-2004) Submitted on behalf of the Pathogen Sequencing Unit, Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, E-mail: mh3@sanger.ac.uk.

    -Holden,M.T.G., Feil,E.J., Lindsay,J.A., Peacock,S.J., Day,N.P.J., Enright,M.C., Foster,T.J., Moore,C.E., Hurst,L., Atkin,R., Barron,A., Bason,N., Bentley,S.D., Chillingworth,C., Chillingworth,T., Churcher,C., Clark,L., Corton,C., Cronin,A., Doggett,J., Do, "Complete genomes of two clinical Staphylococcus aureus strains: Evidence for the rapid evolution of virulence and drug resistance", Proc. Natl. Acad. Sci. U.S.A. 101 (26), 9786-9791 (2004) PUBMED 15213324.

    -Holden,M.T.G., Feil,E.J., Lindsay,J.A., Peacock,S.J., Day,N.P.J., Enright,M.C., Foster,T.J., Moore,C.E., Hurst,L., Atkin,R., Barron,A., Bason,N., Bentley,S.D., Chillingworth,C., Chillingworth,T., Churcher,C., Clark,L., Corton,C., Cronin,A., Doggett,J., Do, "Direct Submission", Submitted (11-SEP-2004) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA.

    -Kenny,J.G., Ward,D., Josefsson,E., Jonsson,I.M., Hinds,J., Rees,H.H., Lindsay,J.A., Tarkowski,A. and Horsburgh,M.J., "The Staphylococcus aureus response to unsaturated long chain free fatty acids: survival mechanisms and virulence implications", PLoS ONE 4 (2), E4344 (2009) PUBMED 19183815 REMARK Publication Status: Online-Only.


DNA sequence : 
ATGGCTAAAATTCCAGTTACGGTATTAAGTGGTTATTTAGGCTCGGGGAAAACAACGTTGTTAAATCATATTTTACAAAA
TCGTGAAGGTCGACGTATCGCAGTAATTGTAAATGATATGAGTGAAGTTAATATCGATAAAGATCTTGTCGCAGATGGTG
GGGGACTATCGCGCACAGACGAAAAATTAGTCGAACTTTCTAACGGTTGTATCTGTTGTACACTTAGAGACGATTTATTA
AAAGAAGTTGAGCGTTTAGTGAAAAAAGGTGGCATCGATCAAATTGTTATTGAGTCAACAGGGATTTCAGAGCCAGTACC
TGTTGCACAAACTTTCTCATATATTGATGATGAACTTGGCATTGATCTTACAGCGATTTGCCGTTTAGATACAATGGTTA
CAGTTGTGGATGCTAACCGCTTCGTCCATGACATCAACTCAGAAGATTTATTGATGGATCGTGATCAAAGCGTTGATGAA
ACAGATGAGCGTTCGATTGCTGATTTATTAATTGACCAAGTTGAATTTTGTGATGTATTGATTATTAATAAAATTGACTT
AATAAGTGAAGAAGAACTAGCGAAGTTAGAAAAAGTGTTAAGTGCATTGCAACCGACTGCTAAAATTATTAAGACAACAA
ATTCTGAAGTAGATTTAAAAGAAGTCTTGAATACGCAGCGTTTTGATTTTGAAAAAGCGAGCGAGTCAGCAGGATGGATC
AAAGAACTTGAGTCTGGTGGGCATGCATCGCATACACCTGAAACAGAAGAATATGGTATATCATCGTTTGTATATAAACG
TCGTCTACCTTTCCATGCTAAAAGGTTCAATGATTGGTTAGAAAGCATGCCAAATAATGTCGTTCGATCAAAAGGTATCG
TATGGTTAGCACAATACAATCATGTAGCATGTTTATTATCTCAAGCAGGGTCATCTTGCAATATTCATCCAGTTACATAT
TGGGTGGCTAGTATGTCTGAAGCGCAACAAACGCAAATATTAGCAGAACGCCAAGACGTCGCAGCTGAATGGGATCCAGA
ATATGGCGATCGTCATACACAATTTGTCATTATTGGTACAGACTTAGATGAAGGTGCAATTACAAAAGAACTCGATGCAT
GCTTAGTCAATGCGCAAGAAATTGATGCAGATTGGCAACAATTTGAAGATCCATATCAATGGCAAATTAGACCGGCACGA
TAA

Protein sequence : 
MAKIPVTVLSGYLGSGKTTLLNHILQNREGRRIAVIVNDMSEVNIDKDLVADGGGLSRTDEKLVELSNGCICCTLRDDLL
KEVERLVKKGGIDQIVIESTGISEPVPVAQTFSYIDDELGIDLTAICRLDTMVTVVDANRFVHDINSEDLLMDRDQSVDE
TDERSIADLLIDQVEFCDVLIINKIDLISEEELAKLEKVLSALQPTAKIIKTTNSEVDLKEVLNTQRFDFEKASESAGWI
KELESGGHASHTPETEEYGISSFVYKRRLPFHAKRFNDWLESMPNNVVRSKGIVWLAQYNHVACLLSQAGSSCNIHPVTY
WVASMSEAQQTQILAERQDVAAEWDPEYGDRHTQFVIIGTDLDEGAITKELDACLVNAQEIDADWQQFEDPYQWQIRPAR