PAI Gene Information


Name : SAR0375 (SAR0375)
Accession : YP_039832.1
PAI name : SaPI4
PAI accession : NC_002952_P1
Strain : Staphylococcus aureus 04-02981
Virulence or Resistance: Not determined
Product : hypothetical protein
Function : -
Note : Poor database matches. N-terminus is similar to Staphylococcus aureus pathogenicity island protein Orf14 TR:Q9F0K4 (EMBL:AF217235) (278 aa) fasta scores: E(): 4.9e-95, 98.545% id in 275 aa. and C-terminus is similar to Staphylococcus aureus pathogenicity
Homologs in the searched genomes :   13 hits    ( 13 protein-level )  
Publication :
    -Holden,M.T.G., "Direct Submission", Submitted (23-JUN-2004) Submitted on behalf of the Pathogen Sequencing Unit, Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, E-mail: mh3@sanger.ac.uk.

    -Holden,M.T.G., Feil,E.J., Lindsay,J.A., Peacock,S.J., Day,N.P.J., Enright,M.C., Foster,T.J., Moore,C.E., Hurst,L., Atkin,R., Barron,A., Bason,N., Bentley,S.D., Chillingworth,C., Chillingworth,T., Churcher,C., Clark,L., Corton,C., Cronin,A., Doggett,J., Do, "Complete genomes of two clinical Staphylococcus aureus strains: Evidence for the rapid evolution of virulence and drug resistance", Proc. Natl. Acad. Sci. U.S.A. 101 (26), 9786-9791 (2004) PUBMED 15213324.

    -Holden,M.T.G., Feil,E.J., Lindsay,J.A., Peacock,S.J., Day,N.P.J., Enright,M.C., Foster,T.J., Moore,C.E., Hurst,L., Atkin,R., Barron,A., Bason,N., Bentley,S.D., Chillingworth,C., Chillingworth,T., Churcher,C., Clark,L., Corton,C., Cronin,A., Doggett,J., Do, "Direct Submission", Submitted (11-SEP-2004) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA.

    -Kenny,J.G., Ward,D., Josefsson,E., Jonsson,I.M., Hinds,J., Rees,H.H., Lindsay,J.A., Tarkowski,A. and Horsburgh,M.J., "The Staphylococcus aureus response to unsaturated long chain free fatty acids: survival mechanisms and virulence implications", PLoS ONE 4 (2), E4344 (2009) PUBMED 19183815 REMARK Publication Status: Online-Only.


DNA sequence :
ATGGAAACAGGTAAAAGTGATGTACTTGATAAAATTGAAAAAATTAATAAAAAAGATAGTGCCTTACAAGAAATTATACC
CAAAGGCTATGAAATTGAACATCATCAATGCGGTGTTGCCTTATATCAACTTATACCAAGTAAAAAAGAAGGCGAACCAG
ATAAAAAGGTTTTTATCACAAATACAATCCCTCAAATTACTGAACGCTTTGAAGATATTGAGAGTAACGAAGTCAGCTTT
AATATGCTTTTCTATGACAATAAAACGCCAGTAAATATAGCTGTGAGTGCCGAAGAAATTTCAGATAGTCGTCAACTCTT
GAAATTGGTTAATAAAAAGCTAGATGTAACATCGTCAACATCTACTAAACTTGTTGACTATATTAATATATCTAAACGGT
ATAATCCACCATTAAATGTTAAAGTTGCAACGCGTTTGGGGCATGTGAAAGGTTATTTTATTTATCCTTATCAAGAAGTA
ATGAAAGACAGCAATGTCAAGTTGTTTAGCAATGATAAAGGGTTTCAAAAGTTAATAGACTCTTTTCGAAGTAAAGGAAC
ACTACAAGGTTACTCTAAAAAGGTGTTTGCTCAAATAAAAGATTTACCAATGGTAATGGTTATGTTGTATGCATCTTTAG
GCTCAGTTTTATTAAGAGAATTTGGATTACAACCCTTTATTGTAGAAATATCAGGTAGTACATCCACAGGTAAAACATTC
ACACTCAACTTAGTATCAAGTGTTTGGGGAACCAGTGACCTTATTACGACATGGAGTTCTACTCAAAATAGTATTGAATC
AATGGCGTCATTTTTGAACTCATTTCCAATGTTTAAAGATGATACGCGTAACACACATCCTAAGTTTGTTGCCAGTGCCA
CATATAACTTTTCTAGTGGTGAAAGTAAATCGAGAAGTAATATTAATTTAACGCTAAATGCTAAAAAAGAATGGCGAAAT
ATTTTAATTTCTACTGGTGAATCATCTATCGCAAATATGGCTGATGAAAAAGCGGGTGTATCAGCACGTGTAGTTACACT
ACAAGATCCACCATATCCAGATAATTTTGATTTTACCACATTAGACAAATCGTTTAGGGAGAACTATGGAACATTAGGGT
TGGCATTTATTAAACAATATGAGTCTAAAAAAGACGTGTATAAGAACGCTTTTGAGAGCTATCAACGGTATTTTAATCAA
AAAGGTAGTAATGAAATCATGCAACGTTTAGGACGTGCCTTTGCGTTACTACAAGTTACCGGTGAGGTTTTGAATGATAT
TGATGGGTTTGAACATGACCATTTTAAAATTATCGAACAAGCCTATGACAGCATGGTTAAAAACAATAAGACGATTGATA
AACCTAAGCAACTGTTAGAGGAACTATTACAATATTTAGATGCGAATAGAAATAATATTGTAGGTGACGGTTATGATTCA
GTAAATTACGGAGATGTTAAAGCGGTATATAAACATGATTTTCTTTGTATTAAAAACGAAACTGTTAAAAATAAATTAGG
ACACGAAATGCAGACGATTACAGGGCAATGGGACAAAAAAGGTTATTTAATAAAAGATAAAAAAAGAATTCAAAAACAAG
TAAAACATAAATCTCAAAGGCATCTGGGTTATGCGATTAAAAAAGAAATAATTGAAGAACTAGGATTTGATTTCTCGATT
TCGCATAATCCATATACAGAAAGTTATTAG

Protein sequence :
METGKSDVLDKIEKINKKDSALQEIIPKGYEIEHHQCGVALYQLIPSKKEGEPDKKVFITNTIPQITERFEDIESNEVSF
NMLFYDNKTPVNIAVSAEEISDSRQLLKLVNKKLDVTSSTSTKLVDYINISKRYNPPLNVKVATRLGHVKGYFIYPYQEV
MKDSNVKLFSNDKGFQKLIDSFRSKGTLQGYSKKVFAQIKDLPMVMVMLYASLGSVLLREFGLQPFIVEISGSTSTGKTF
TLNLVSSVWGTSDLITTWSSTQNSIESMASFLNSFPMFKDDTRNTHPKFVASATYNFSSGESKSRSNINLTLNAKKEWRN
ILISTGESSIANMADEKAGVSARVVTLQDPPYPDNFDFTTLDKSFRENYGTLGLAFIKQYESKKDVYKNAFESYQRYFNQ
KGSNEIMQRLGRAFALLQVTGEVLNDIDGFEHDHFKIIEQAYDSMVKNNKTIDKPKQLLEELLQYLDANRNNIVGDGYDS
VNYGDVKAVYKHDFLCIKNETVKNKLGHEMQTITGQWDKKGYLIKDKKRIQKQVKHKSQRHLGYAIKKEIIEELGFDFSI
SHNPYTESY