Name : SAR0069 (SAR0069)
Accession : YP_039537.1
PAI name : Type-II SCCmec
PAI accession : NC_002952_R1
Strain : Staphylococcus aureus 04-02981
Virulence or Resistance: Not determined
Product : sensor kinase
Function : -
Note : Two-component regulatory system family, sensor kinase. Similar to Clostridium acetobutylicum histidine kinase sensor protein KdpD SW:KDPD_CLOAB (P94608) (900 aa) fasta scores: E(): 1.2e-75, 29.538% id in 887 aa, and to Rhizobium loti two-component sensor
Homologs in the searched genomes : 62 hits ( 62 protein-level )
Publication :
-Holden,M.T.G., "Direct Submission", Submitted (23-JUN-2004) Submitted on behalf of the Pathogen Sequencing Unit, Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, E-mail: mh3@sanger.ac.uk.
-Holden,M.T.G., Feil,E.J., Lindsay,J.A., Peacock,S.J., Day,N.P.J., Enright,M.C., Foster,T.J., Moore,C.E., Hurst,L., Atkin,R., Barron,A., Bason,N., Bentley,S.D., Chillingworth,C., Chillingworth,T., Churcher,C., Clark,L., Corton,C., Cronin,A., Doggett,J., Do, "Complete genomes of two clinical Staphylococcus aureus strains: Evidence for the rapid evolution of virulence and drug resistance", Proc. Natl. Acad. Sci. U.S.A. 101 (26), 9786-9791 (2004) PUBMED 15213324.
-Holden,M.T.G., Feil,E.J., Lindsay,J.A., Peacock,S.J., Day,N.P.J., Enright,M.C., Foster,T.J., Moore,C.E., Hurst,L., Atkin,R., Barron,A., Bason,N., Bentley,S.D., Chillingworth,C., Chillingworth,T., Churcher,C., Clark,L., Corton,C., Cronin,A., Doggett,J., Do, "Direct Submission", Submitted (11-SEP-2004) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA.
-Kenny,J.G., Ward,D., Josefsson,E., Jonsson,I.M., Hinds,J., Rees,H.H., Lindsay,J.A., Tarkowski,A. and Horsburgh,M.J., "The Staphylococcus aureus response to unsaturated long chain free fatty acids: survival mechanisms and virulence implications", PLoS ONE 4 (2), E4344 (2009) PUBMED 19183815 REMARK Publication Status: Online-Only.
| DNA sequence : | |
ATGGATAATATGTTGTATATTAATTATGATGTGATTAAGAGGGGGTGCCTCATGGAAAGTACATATAAAAAAAGAGGGAA
ACTTACCATTTATTTAGGCTATAGCCCAGGGGTAGGTAAAACGTATGAAATGTTATCAAATGGTATTGATCAGTATCAAG
AAGGTGCAGATATTAAAATTGGTTATATCGAACCCCATCAACGCCCTGAAACCAATGCACTGGTTCAACAATTGCCTGAA
ATTTCGACCTCCAGCCGTAAATTTGGCAGCCACACCTTTCACTATATAGATGTCTCTAAAATCATAGAAGCTAATCCAGA
TGTGGTCTTAATTGATGAACTAGCACATACAAACATTTCAAAAGAGCGCCATTTAAAACGTTATAAGGATATAGAAGAAA
TTCTATCGCATGGTATCGATGTCTGGACAACACTCAACATCCAACATATCGAGAGTCTAAGCGGACAAATTGCGTTAATG
ACAGGTATTCAAGTTACAGAACGTGTGCCCGACCAATTCATTACGTCAGCAGATGCCTTTGAAGTTGTGGATATTTCACC
AAATATGTTGATTCAGCGCCTTAAAGCAGGAAAAGTATATAAAAAAGAACGCTTAGAAACAGCCTTTTCTAATTTCTTTA
CGTATGAAAATCTGACAGAGCTGCGTGAACTTACACTCAGAACTGTCGCAGATATTATGAGTCAAAAAGGACAACAATAT
AAAACTAAACATACCGACATTACACCGCATATTGCGGTAGCTATCAGCGGCAGTATTTATAACGAACGGGTCATACGAGA
AGCAAGACGTGCTGCCTATAAAGAACATGCTAAATTCACAGCTGTGTATATTGATGTCTTTGAGACACCGTCAGAAAGCA
GAAAACAAGATCATTATGTCCATAAAAATCTAATGCTCGCCAAAGCGTTAGGTGCAGAAATCAAAGTGTTGTATGCACAA
GATATTGCGAAAGCGTTAACCGATTGGTGTGATCTCGCTTTTGTGACGAAGCTAGTCCTTGGACAGTCAGAACAGCCACG
TTGGAAAGATTACTTTAAACAGTCACTCATTGAACAAATTAATCACGTACCACACCATTTCAAGTTAGAAATTGTACCGA
TTCATTATATTCATTCAGACAAACCTACAAATACACCTAAGCAAGCTCAAAAATCCTCTCGTTTAACTGTAGAGATTATG
AAGATGCTTGTAATTCAAACGATCTGTGTCTTGCTCGGTATATGGGTTTACAACTTAGATAAAAGCGAATCCAGTGCCAT
TATCTTGCTGATGTTCTTTATCGGTATTATCGTGCTTTCTATTTGGACCCAATCCTATTTAATCGGATTCTTTGCGTCTA
TCTTAAATGTGTTTGTTTTTAATTATTTCTTTACGGTGCCAAGATTCACTTTAGAAATGTATCGCTTTGAATATCCGATT
ACGTTTGCGACCAGTATTTTTGCTAGTATCTTTACGAGTGCCATCTTAAAGAATTTAAAACATCAGCATTCCTTAACAGA
ACGGCAGTTATATCGGACCAATATTATGCTGCAATTTAACCAGTCCATTAAAGAATCTTATTCAATTGAACGCTTATTAA
ATATTGCTGGTGATCAGATTCATCAGCTACTCAATCAGGATGTCACGGTATTCTTAATTCAAAGTAAGAAAGTCGCTGCT
TCCAACTCATTTGGAAACAGAAGCATTTCAAGCTCAGATAAGACACATGATGCTGAGACATTGAGCTGGGTCATTGAAAA
TGAAAGCCGTGCCGGTAAATTAACCGATACCTTTCCTGGCAGTAAATTTTTGTGTATTCCCATTGGCACAAATCCAGTCA
AAGGTGTGATTTCTATCCGCTTCACCGACGAAACTTACATCGACACCTATGACAATTCAATATTAGACTCTATGTTGAAC
GATATTACCCTGGCAATAGAGAATGTGGATCTATTAAAACAAACCAGACAATCCATATTGAAAGCTGAACGAGAAGCCAC
ACGTTCAAACTTCTTGCATTCAATTTCACATGATATTAGAACACCACTGACTTCCATTATGGGCAACTTAGATATGCTGA
AATACCATAACGAGCATTTAAACGATCAACAACAAGCAGAACTCTTAACTGCTTCTTATGGCGAAGCACAATATCTGCAT
ACCTTAGTCACAAATATTTTATCTTTGACTAAGTTAGAAAGCTCTGACATTCAAATACAACGCACCCCTTATTTAGTAGA
AGAACTTCTAGAAGAATTTGAAGAAGGCCTCATACGCAGACACCAAGCAAATCATGTCATTATTGAAAATGAGGATGACG
CTTCACTCATTAATATCGACAGTAAATTAATACTGCAAGTGCTATTCAACCTTATCGATAATGCTTTAAAGCATGCAGAA
TCACATTCTGAAATAAAACTGCACGTTCAACATGAAACAAACAAAATAAAATTCGAAATGATAGATTGCGGAAAAGGTAT
TCCAGAAGAAGAACGTCAATTGATTTTTAATCCCTATTATTCAGGAGACAACTTTAAAGACAATAAAAAAGATAGTTTGG
GATTAGGGCTCTATTTAGTACAACTCATCTTGAAACAACACAACAGTGAATTAGAATATCAACCGAATACACCACAAGGC
AGTATTTTTTATTTTTATTTGACTGTTAATCCAATTGAAATGGAGGGAGCCATGGATGAAAACAACATTATTGGTCGTTG
A
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| Protein sequence : | |
MDNMLYINYDVIKRGCLMESTYKKRGKLTIYLGYSPGVGKTYEMLSNGIDQYQEGADIKIGYIEPHQRPETNALVQQLPE
ISTSSRKFGSHTFHYIDVSKIIEANPDVVLIDELAHTNISKERHLKRYKDIEEILSHGIDVWTTLNIQHIESLSGQIALM
TGIQVTERVPDQFITSADAFEVVDISPNMLIQRLKAGKVYKKERLETAFSNFFTYENLTELRELTLRTVADIMSQKGQQY
KTKHTDITPHIAVAISGSIYNERVIREARRAAYKEHAKFTAVYIDVFETPSESRKQDHYVHKNLMLAKALGAEIKVLYAQ
DIAKALTDWCDLAFVTKLVLGQSEQPRWKDYFKQSLIEQINHVPHHFKLEIVPIHYIHSDKPTNTPKQAQKSSRLTVEIM
KMLVIQTICVLLGIWVYNLDKSESSAIILLMFFIGIIVLSIWTQSYLIGFFASILNVFVFNYFFTVPRFTLEMYRFEYPI
TFATSIFASIFTSAILKNLKHQHSLTERQLYRTNIMLQFNQSIKESYSIERLLNIAGDQIHQLLNQDVTVFLIQSKKVAA
SNSFGNRSISSSDKTHDAETLSWVIENESRAGKLTDTFPGSKFLCIPIGTNPVKGVISIRFTDETYIDTYDNSILDSMLN
DITLAIENVDLLKQTRQSILKAEREATRSNFLHSISHDIRTPLTSIMGNLDMLKYHNEHLNDQQQAELLTASYGEAQYLH
TLVTNILSLTKLESSDIQIQRTPYLVEELLEEFEEGLIRRHQANHVIIENEDDASLINIDSKLILQVLFNLIDNALKHAE
SHSEIKLHVQHETNKIKFEMIDCGKGIPEEERQLIFNPYYSGDNFKDNKKDSLGLGLYLVQLILKQHNSELEYQPNTPQG
SIFYFYLTVNPIEMEGAMDENNIIGR
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