Name : mecR1 (SARLGA251_00270)
Accession : YP_005754042.1
PAI name : Type-XI SCCmec
PAI accession : NC_017349_R1
Strain : Staphylococcus aureus 04-02981
Virulence or Resistance: Resistance
Product : methicillin resistance protein MecR1
Function : -
Note : Similar to Staphylococcus aureus mecr1 recname: full=methicillin resistance mecr1 protein UniProt:P0A0B1 (EMBL:L14020) (585 aa) fasta scores: E()=4.7e-106, 44.8% id in 585 aa
Homologs in the searched genomes : 14 hits ( 14 protein-level )
Publication :
-Garcia-Alvarez,L., Holden,M.T., Lindsay,H., Webb,C.R., Brown,D.F., Curran,M.D., Walpole,E., Brooks,K., Pickard,D.J., Teale,C., Parkhill,J., Bentley,S.D., Edwards,G.F., Girvan,E.K., Kearns,A.M., Pichon,B., Hill,R.L., Larsen,A.R., Skov,R.L., Peacock,S.J., M, "Meticillin-resistant Staphylococcus aureus with a novel mecA homologue in human and bovine populations in the UK and Denmark: a descriptive study", Lancet Infect Dis 11 (8), 595-603 (2011) PUBMED 21641281.
-Garcia-Alvarez,L., Holden,M.T., Lindsay,H., Webb,C.R., Brown,D.F., Curran,M.D., Walpole,E., Brooks,K., Pickard,D.J., Teale,C., Parkhill,J., Bentley,S.D., Edwards,G.F., Girvan,E.K., Kearns,A.M., Pichon,B., Hill,R.L., Larsen,A.R., Skov,R.L., Peacock,S.J., M, "Direct Submission", Submitted (05-APR-2012) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA.
-Holden,M., "Direct Submission", Submitted (02-FEB-2011) to the INSDC. Holden M., Pathogen Sequencing Unit, The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UNITED KINGDOM.
| DNA sequence : | |
TTGCTACAACAATTCTTGATAATGAGTATAATTAGTTCAATTATGACTTTGTTATTAATTATGATTGTCCGTATTATATG
TATTAAGTATTTTAAGGCTCAGTTAAATCATAAAGTTTGGTTACTAGTTGTTCTTTCAATATTTTTACCTTTAATACCGA
TAAATAATTTATTGCAACTTAACATTCCAGGTATACTTTCATCTGATATGATTTCACATTCATCTAAGTCTATAAATCAT
AATTTATCAAATGAAAATACTAATTTAACAAAAGATTTAGCTTTGGATATCCAGCATCATGAAATGCCGTTTATCCTAAT
TATTTTACTAGTAGTTTGGTTTATTGGATTAATATTTTTTAGCTTTAAATTTATTTCTGCTATTAAGCAAATTGCCTTTA
TAAAAGACTTGTCTATTAGATCTCCAATATTAGATAACCAATTAAAAAAATGTATAAATGATTTAAACATCAAAGAAAAA
TCTATTGCAATTATTCATGTAGATGAAGTAGAGAATCCAATGGTCTTTTGGCTAGGAAAGTACTATATTGTTTTGCCTAC
AAATATAATGGATATGATGGAAGAAGAAGAAATTGATTATATAATTAGCCATGAACTCATTCATATTAAGAATAAGGATT
TATGGGGCAATTATATATTCACAATTTTCACTAGTATAGTATGGTTCAATCCAGCATTACATTTAGCAAAAAAATTATTT
AATATTGATTGTGAAATTTCATGTGATAATCAAGTTCTTACAAAATTAAGTCAATCAAATCACACAAGCTATGGTAAGGC
AATTTTGAAATGTTGGGCTATACAGAAACAATCAGTTAATAATTTTGCAGCAAAATATTTATTAGGCACACAATCTAATT
TAAAGAGTCGTATTGTGAATGTTTCAAAATTTAAAAATACTCGAAATCGTAAATGGAAATTCTTACCCTATGTGGTTTTA
TCTGTATTGATTTTACTGCAAGGGTTGATGGTTTCTGATCATTCTGACAAGAATGAATATACGGATGATATCAAATACAC
AAACTTGAAAGGATTAGGTTCTCATTTCTCAGGTTTTAAGGGTAGCTTTGTATTATATGATAATCAGAAAAAAGAGTATT
TCTTATATAACGAAAAAGAAAGTAGAAAAAGATACACACCTGATTCTACATATAAACCGTATTTAGCATTAATTGGATTT
GATAAAAATGTTATGTCATTGAATAATACTGAACAAAAATGGAATGGCAATGAAAATGTTTTTAAAGAATGGAATCAAAA
TCAAAATTTAAGTTCAGCAATGAGGTATTCTGTGAATTGGTATTTTGAGAATATAGATAGAAGTATAAAAAATAAAGATC
TTAAAAATTATATAAGTGAATTACAGTATGGTAATGAAAACATATCAGGAAGTAAAAATTATTGGAATGAGTCCTCTTTA
AAAATTTCTGCAATAGAACAAGTTAAGTTGTTAATGAAGATAGATAATCAACAACTTAAATTTGATGAAAATTATATCAA
CGCTGTAAAAGATAGTATTACGCTAAAAAAAGCTAACCAATATAGATATCTAGGTAAAACTGGAACAGGTATTATAAACG
GCAAGGAAACGAATGGATGGTTTATTGGAACAATTGAGAAAAACGGAAAATCTTACTACTTTGCCACACACTTAGACGGT
AAGAATAATGCCAGTGGTAAGAAAGCGAAAGATATTTCTGAAAAAATTCTTGAAGAAATGGAGTTAATGCAATGA
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| Protein sequence : | |
MLQQFLIMSIISSIMTLLLIMIVRIICIKYFKAQLNHKVWLLVVLSIFLPLIPINNLLQLNIPGILSSDMISHSSKSINH
NLSNENTNLTKDLALDIQHHEMPFILIILLVVWFIGLIFFSFKFISAIKQIAFIKDLSIRSPILDNQLKKCINDLNIKEK
SIAIIHVDEVENPMVFWLGKYYIVLPTNIMDMMEEEEIDYIISHELIHIKNKDLWGNYIFTIFTSIVWFNPALHLAKKLF
NIDCEISCDNQVLTKLSQSNHTSYGKAILKCWAIQKQSVNNFAAKYLLGTQSNLKSRIVNVSKFKNTRNRKWKFLPYVVL
SVLILLQGLMVSDHSDKNEYTDDIKYTNLKGLGSHFSGFKGSFVLYDNQKKEYFLYNEKESRKRYTPDSTYKPYLALIGF
DKNVMSLNNTEQKWNGNENVFKEWNQNQNLSSAMRYSVNWYFENIDRSIKNKDLKNYISELQYGNENISGSKNYWNESSL
KISAIEQVKLLMKIDNQQLKFDENYINAVKDSITLKKANQYRYLGKTGTGIINGKETNGWFIGTIEKNGKSYYFATHLDG
KNNASGKKAKDISEKILEEMELMQ
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