PAI Gene Information


Name : aphA (smi_1708)
Accession : YP_003446810.1
PAI name : The aminoglycoside resistance gene cluster
PAI accession : NC_013853_P1
Strain : Streptococcus mitis B6
Virulence or Resistance: Resistance
Product : aminoglycoside 3'-phosphotransferase
Function : -
Note : -
Homologs in the searched genomes :   18 hits    ( 18 protein-level )  
Publication :
    -Denapaite,D., Bruckner,R., Nuhn,M., Reichmann,P., Henrich,B., Maurer,P., Schahle,Y., Selbmann,P., Zimmermann,W., Wambutt,R. and Hakenbeck,R., "The genome of Streptococcus mitis B6--what is a commensal?", PLoS ONE 5 (2), E9426 (2010) PUBMED 20195536 REMARK Publication Status: Online-Only.

    -Denapaite,D., Bruckner,R., Nuhn,M., Reichmann,P., Henrich,B., Maurer,P., Schahle,Y., Selbmann,P., Zimmermann,W., Wambutt,R. and Hakenbeck,R., "Direct Submission", Submitted (17-FEB-2010) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA.

    -Nuhn,M., "Direct Submission", Submitted (12-NOV-2009) Nuhn M., Department of Microbiology, University of Kaiserslautern, Paul-Ehrlich-Strasse, 67663 Kaiserslautern, GERMANY.


DNA sequence : 
ATGGCTAAAATGAGAATATCACCGGAATTGAAAAAACTGATCGAAAAATACCGCTGCGTAAAAGATACGGAAGGAATGTC
TCCTGCTAAGGTATATAAGCTGGTGGGAGAAAATGAAAACCTATATTTAAAAATGACGGACAGCCGGTATAAAGGGACCA
CCTATGATGTGGAACGAGAAAAGGACATGATGCTATGGCTGGAAGGAAAGCTGCCTGTTCCAAAGGTCCTGCACTTTGAA
CGGCATGATGGCTGGAGCAATCTGCTCATGAGTGAGGCCGATGGCGTCCTTTGCTCGGAAGAGTATGAAGATGAACAAAG
CCCTGAAAAGATTATCGAGCTGTATGCGGAGTGCATCAGGCTCTTTCACTCCATCGACATATCGGATTGTCCCTATACGA
ATAGCTTAGACAGCCGCTTAGCCGAATTGGATTACTTACTGAATAACGATCTGGCCGATGTGGATTGCGAAAACTGGGAA
GAAGACACTCCATTTAAAGATCCGCGCGAGCTGTATGATTTTTTAAAGACGGAAAAGCCCGAAGAGGAACTTGTCTTTTC
CCACGGCGACCTGGGAGACAGCAACATCTTTGTGAAAGATGGCAAAGTAAGTGGCTTTATTGATCTTGGGAGAAGCGGCA
GGGCGGACAAGTGGTATGACATTGCCTTCTGCGTCCGCTCGATCAGGGAGGATATCGGGGAAGAACAGTATGTCGAGCTA
TTTTTTGACTTACTGGGGATCAAGCCTGATTGGGAGAAAATAAAATATTATATTTTACTGGATGAATTGTTTTAG

Protein sequence : 
MAKMRISPELKKLIEKYRCVKDTEGMSPAKVYKLVGENENLYLKMTDSRYKGTTYDVEREKDMMLWLEGKLPVPKVLHFE
RHDGWSNLLMSEADGVLCSEEYEDEQSPEKIIELYAECIRLFHSIDISDCPYTNSLDSRLAELDYLLNNDLADVDCENWE
EDTPFKDPRELYDFLKTEKPEEELVFSHGDLGDSNIFVKDGKVSGFIDLGRSGRADKWYDIAFCVRSIREDIGEEQYVEL
FFDLLGIKPDWEKIKYYILLDELF