Name : thyA (cur_1520)
Accession : YP_001800914.1
PAI name : Not named
PAI accession : NC_010545_R1
Strain : Corynebacterium urealyticum DSM 7109
Virulence or Resistance: Not determined
Product : thymidylate synthase
Function : -
Note : ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived
Homologs in the searched genomes : 1102 hits ( 1102 protein-level )
Publication :
-Linke,B., "Direct Submission", Submitted (18-FEB-2008) Linke B., Center For Biotechnology, Bielefeld University, Universitaetsstrasse 25, 33501 Bielefeld, GERMANY.
-Tauch,A., Trost,E., Tilker,A., Ludewig,U., Schneiker,S., Goesmann,A., Arnold,W., Bekel,T., Brinkrolf,K., Brune,I., Gotker,S., Kalinowski,J., Kamp,P.B., Lobo,F.P., Viehoever,P., Weisshaar,B., Soriano,F., Droge,M. and Puhler,A., "The lifestyle of Corynebacterium urealyticum derived from its complete genome sequence established by pyrosequencing", J. Biotechnol. 136 (1-2), 11-21 (2008) PUBMED 18367281.
-Tauch,A., Trost,E., Tilker,A., Ludewig,U., Schneiker,S., Goesmann,A., Arnold,W., Bekel,T., Brinkrolf,K., Brune,I., Gotker,S., Kalinowski,J., Kamp,P.B., Lobo,F.P., Viehoever,P., Weisshaar,B., Soriano,F., Droge,M. and Puhler,A., "Direct Submission", Submitted (03-APR-2008) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA.
DNA sequence : | |
ATGTCAGAGGCTCAAACTTCCCCCACCATCGCCACGCCCTACGAGGACCTGCTCTCCAAGATCCTCGCGGAGGGCGCCAA
GAAGGACGACCGCACCGGCACCGGCACGACGTCCCTGTTCGGTCAGCAGATCCGCTTTAATCTGGCGGAGTCCTTCCCGC
TGATTACGACGAAGTCCGTGCACGTGAAGTCCGTGGTCGGCGAGCTGTTGTGGTTCCTCTCCGGGGACTCCAACGTCCGC
TGGCTGCAGGATAACGGCATCCGCATCTGGAACGAGTGGGCCGATGAGGACGGCGACCTGGGCCCGGTCTACGGCGTGCA
GTGGCGCAGCTGGCCGACCCCGGATGGCCGCCATATCGACCAGATCTCCCAGGCACTGGAGATGCTGAAGCAGAACCCAG
ATTCCCGCCGGAACATCGTCAGCGCGTGGAATGTCTCGGAGCTGGAGAACATGGCGCTTCCGCCCTGCCACCTGCTGTTC
CAGCTGTACGTGGCCGATGGGAAGCTCTCCTGCCAGCTCTACCAGCGCAGCGCGGACATGTTCCTGGGCGTGCCATTCAA
CATCGCCAGCTATTCGCTGCTGACCCACATGTTCGCCCAGCAGACGGGCCTGGAGGTCGGCGAGTTCATCTGGACCGGTG
GGGACTGCCACATCTACGACAACCACCGCGAGCAGGTGGAGCTGCAGCTTTCGCGCGAACCGCGCCCCTATCCGCAGCTG
GAGCTGACTAAGGCCAAGGACATGTTCAGCTATGGCTTCGAGGACGTGAACTTCGTGGGCTACGACCCGCACCCGGTGAT
TAAGGCAAAGGTGGCTGTGTAA
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Protein sequence : | |
MSEAQTSPTIATPYEDLLSKILAEGAKKDDRTGTGTTSLFGQQIRFNLAESFPLITTKSVHVKSVVGELLWFLSGDSNVR
WLQDNGIRIWNEWADEDGDLGPVYGVQWRSWPTPDGRHIDQISQALEMLKQNPDSRRNIVSAWNVSELENMALPPCHLLF
QLYVADGKLSCQLYQRSADMFLGVPFNIASYSLLTHMFAQQTGLEVGEFIWTGGDCHIYDNHREQVELQLSREPRPYPQL
ELTKAKDMFSYGFEDVNFVGYDPHPVIKAKVAV
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