PAI Gene Information


Name : set7nm (NWMN_0394)
Accession : YP_001331428.1
PAI name : vSa_alpha
PAI accession : NC_009641_P1
Strain : Staphylococcus aureus 04-02981
Virulence or Resistance: Virulence
Product : superantigen-like protein 7
Function : -
Note : SSL7, SET1; blocks IgA-FcR interactions and inhibits complement, leading to increased survival of a sensitive bacterium in blood
Homologs in the searched genomes :   188 hits    ( 188 protein-level )  
Publication :
    -Baba,T., Bae,T., Schneewind,O. and Hiramatsu,K., "Direct Submission", Submitted (15-FEB-2007) Tadashi Baba, Juntendo University School of Medicine, Department of Bacteriology; 2-1-1 Hongo, Bunkyo, Tokyo 113-8421, Japan (E-mail:tbaba@med.juntendo.ac.jp, Tel:81-3-5802-1041, Fax:81-3-5684-7830).

    -Baba,T., Bae,T., Schneewind,O., Takeuchi,F. and Hiramatsu,K., "Genome sequence of Staphylococcus aureus strain Newman and comparative analysis of staphylococcal genomes: polymorphism and evolution of two major pathogenicity islands", J. Bacteriol. 190 (1), 300-310 (2008) PUBMED 17951380.

    -Baba,T., Bae,T., Schneewind,O., Takeuchi,F. and Hiramatsu,K., "Direct Submission", Submitted (06-JUL-2007) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA.


DNA sequence :
GTGAAATTAAAAACGTTAGCTAAAGCAACATTGGCATTAGGCTTATTAACTACTGGTGTGATTACATCAGAAGGCCAAGC
AGTTCAAGCAAAAGAAAAGCAAGAGAGAGTACAACATTTATATGATATTAAAGACTTACATCGATACTACTCATCAGAAA
GTTTTGAATTCAGTAATATTAGTGGTAAGGTTGAAAATTATAACGGTTCTAACGTTGTACGCTTTAACCAAGAAAATCAA
AATCACCAATTATTCTTATTAGGTAAAGATAAAGAGAAATATAAAGAAGGCATTGAAGGCAAAGATGTCTTTGTGGTAAA
AGAATTAATTGATCCAAACGGTAGATTATCTACTGTTGGTGGTGTGACTAAGAAAAATAACAAATCTTCTGAAACTAATA
CACATTTATTTGTTAATAAAGTGTATGGCGGAAATTTAGATGCATCAATTGACTCATTTTCAATTAATAAAGAAGAAGTT
TCACTGAAAGAACTTGATTTCAAAATTAGACAACATTTAGTTAAAAATTATGGTTTATATAAAGGTACGACTAAATACGG
TAAGATCACTATCAATTTGAAAGATGGAGAAAAGCAAGAAATTGATTTAGGTGATAAATTGCAATTCGAGCGCATGGGTG
ATGTGTTGAATAGTAAGGATATTAATAAGATTGAAGTGACTTTGAAACAAATTTAA

Protein sequence :
MKLKTLAKATLALGLLTTGVITSEGQAVQAKEKQERVQHLYDIKDLHRYYSSESFEFSNISGKVENYNGSNVVRFNQENQ
NHQLFLLGKDKEKYKEGIEGKDVFVVKELIDPNGRLSTVGGVTKKNNKSSETNTHLFVNKVYGGNLDASIDSFSINKEEV
SLKELDFKIRQHLVKNYGLYKGTTKYGKITINLKDGEKQEIDLGDKLQFERMGDVLNSKDINKIEVTLKQI