PAI Gene Information


Name : guaA (NWMN_0381)
Accession : YP_001331415.1
PAI name : vSa_alpha
PAI accession : NC_009641_P1
Strain : Staphylococcus aureus 04-02981
Virulence or Resistance: Not determined
Product : GMP synthase
Function : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway
Homologs in the searched genomes :   2240 hits    ( 2240 protein-level )  
Publication :
    -Baba,T., Bae,T., Schneewind,O. and Hiramatsu,K., "Direct Submission", Submitted (15-FEB-2007) Tadashi Baba, Juntendo University School of Medicine, Department of Bacteriology; 2-1-1 Hongo, Bunkyo, Tokyo 113-8421, Japan (E-mail:tbaba@med.juntendo.ac.jp, Tel:81-3-5802-1041, Fax:81-3-5684-7830).

    -Baba,T., Bae,T., Schneewind,O., Takeuchi,F. and Hiramatsu,K., "Genome sequence of Staphylococcus aureus strain Newman and comparative analysis of staphylococcal genomes: polymorphism and evolution of two major pathogenicity islands", J. Bacteriol. 190 (1), 300-310 (2008) PUBMED 17951380.

    -Baba,T., Bae,T., Schneewind,O., Takeuchi,F. and Hiramatsu,K., "Direct Submission", Submitted (06-JUL-2007) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA.


DNA sequence :
ATGGAAATGGCAAAAGAACAAGAGTTAATCCTTGTCTTAGACTTTGGTAGCCAATACAACCAATTAATTACACGCCGAAT
TCGTGAAATGGGCGTTTATAGTGAATTACACGATCATGAAATTTCAATTGAAGAAATTAAGAAAATGAATCCAAAAGGTA
TTATCTTATCAGGTGGTCCAAATTCAGTTTATGAAGAAGGTTCATTTACAATTGATCCGGAAATATATAATTTAGGAATT
CCAGTACTTGGTATTTGTTACGGCATGCAATTAACTACTAAATTATTAGGTGGTAAAGTTGAACGTGCCAATGAACGTGA
ATACGGTAAAGCAATCATTAATGCGAAGTCAGATGAGTTATTCGCTGGCTTACCAGCAGAACAAACTGTTTGGATGAGTC
ATTCTGATAAAGTTATTGAAATTCCAGAAGGCTTTGAAGTTATCGCTGATAGCCCAAGCACAGACTATGCAGCAATCGAA
GATAAGAAACGTCGCATTTATGGTGTTCAATTCCATCCAGAAGTACGTCATACAGAATATGGTAATGATTTATTAAATAA
TTTTGTCCGTCGTGTTTGTGATTGTAGAGGTCAATGGACAATGGAAAACTTTATCGAAATCGAAATTGAAAAGATTCGTC
AACGCGTAGGAGACCGTCGTGTATTATGTGCGATGAGTGGCGGCGTAGATTCATCTGTTGTAGCTGTACTATTGCATAAA
GCAATAGGTGATCAACTAACATGTATCTTTGTAGACCATGGCTTACTTCGTAAAGGTGAAGGCGACATGGTTATGGAGCA
ATTCGGTGAAGGTTTCAACATGAATATTATTCGTGTTAATGCGAAAGATCGCTTTATGAATAAATTAAAAGGTGTTTCAG
ATCCTGAACAAAAACGTAAAATCATTGGTAATGAATTTGTATACGTATTTGATGATGAAGCATCAAAACTGAAAGGTGTA
GACTTCCTTGCGCAAGGAACACTATATACAGACGTCATCGAATCAGGTACTAAAACAGCACAAACAATCAAATCACACCA
CAATGTTGGTGGATTACCAGAAGACATGGAATTCGAATTAATCGAACCAATCAATACATTGTTTAAAGATGAAGTACGTA
AATTAGGTATTGAGTTAGGTATTCCAGAACATTTAGTATGGAGACAACCATTCCCAGGACCTGGTCTTGGTATTCGTGTA
CTTGGAGAAATTACTGAAGATAAACTAGAAATCGTTAGAGAATCAGACGCGATTTTACGCCAAGTGATTAGAGAAGAAGG
TCTTGAAAGAGAAATTTGGCAATACTTCACAGTGTTACCAAACATTCAATCAGTAGGTGTTATGGGAGACTACCGTACGT
ATGATCACACAGTAGGTATTCGTGCAGTAACATCTATCGACGGTATGACAAGTGACTTCGCACGCATCGATTGGGAAGTC
TTACAAAAGATTTCTAGTCGTATCGTAAACGAAGTAGATCACGTCAACCGCGTAGTCTATGACATTACATCAAAACCACC
AAGCACAATTGAGTGGGAATAA

Protein sequence :
MEMAKEQELILVLDFGSQYNQLITRRIREMGVYSELHDHEISIEEIKKMNPKGIILSGGPNSVYEEGSFTIDPEIYNLGI
PVLGICYGMQLTTKLLGGKVERANEREYGKAIINAKSDELFAGLPAEQTVWMSHSDKVIEIPEGFEVIADSPSTDYAAIE
DKKRRIYGVQFHPEVRHTEYGNDLLNNFVRRVCDCRGQWTMENFIEIEIEKIRQRVGDRRVLCAMSGGVDSSVVAVLLHK
AIGDQLTCIFVDHGLLRKGEGDMVMEQFGEGFNMNIIRVNAKDRFMNKLKGVSDPEQKRKIIGNEFVYVFDDEASKLKGV
DFLAQGTLYTDVIESGTKTAQTIKSHHNVGGLPEDMEFELIEPINTLFKDEVRKLGIELGIPEHLVWRQPFPGPGLGIRV
LGEITEDKLEIVRESDAILRQVIREEGLEREIWQYFTVLPNIQSVGVMGDYRTYDHTVGIRAVTSIDGMTSDFARIDWEV
LQKISSRIVNEVDHVNRVVYDITSKPPSTIEWE