PAI Gene Information


Name : tcpI (VC0395_A0350)
Accession : YP_001216306.1
PAI name : VPI-1
PAI accession : NC_009457_P1
Strain : Vibrio cholerae IEC224
Virulence or Resistance: Virulence
Product : toxin co-regulated pilus biosynthesis protein I
Function : -
Note : identified by match to protein family HMM PF00015; match to protein family HMM PF00672
Homologs in the searched genomes :   7 hits    ( 7 protein-level )  
Publication :
    -Feng,L., Reeves,P.R., Lan,R., Ren,Y., Gao,C., Zhou,Z., Ren,Y., Cheng,J., Wang,W., Wang,J., Qian,W., Li,D. and Wang,L., "A recalibrated molecular clock and independent origins for the cholera pandemic clones", PLoS ONE 3 (12), E4053 (2008) PUBMED 19115014.

    -Feng,L., Reeves,P.R., Lan,R., Ren,Y., Gao,C., Zhou,Z., Ren,Y., Cheng,J., Wang,W., Wang,J., Qian,W., Li,D. and Wang,L., "Direct Submission", Submitted (18-MAY-2007) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA.

    -Heidelberg,J., "Direct Submission", Submitted (16-MAR-2007) The Institute for Genomic Research, 9712 Medical Center Drive, Rockville, MD 20850, USA.


DNA sequence :
ATGATAAAAAAAATAATTTCGGTTTTTTTATTACTTGCGTGCATCATTACGTCGGCTTTTACTGCCTTTTTCTATCACTC
GAAACTATCAGATCAAACAAAATCTATATCTAGCCTTAGTTCTCAGCAGGCACAAGAACGGTTGCAAAGTTATCAGGATT
CTTTAGATTTTTATAAAAAACTTAATATCTCTCTCTCAGTTGCAATAGCCAATTCACTTCGCGATAAAGCAGTCGAAGAA
CTCAACGCTATTGCTTTACGTATACAGGAAAATCATGGATTTATTGGTGTTACCTTCGCTAGTTTAGATGGCACCATGTT
TACAGATATTGGTACTCTAGATTGGAATGCAAAGACATTGAGAAGAGATTGGTTTGTTAAAACGGTCGAACTCGGTACTA
AACATTACACAGCTTTTGATATCGATAAAACAACTGGGCAACACGTTCTCACTATTGCCACCCCTGTTTATGTAGGCAAC
GACATTGTCGGCAGTGTCGCTTTAGATATTGCAGGTGATCAGATTGCCTCACCTAACGGCAGTGGGATGTTTATGATGAC
GGATAGGAATTTTAATGTATTTGCATCTGATCTCACTCACAGTACCTTAATTGGAAAAGATTTAACGAAAGAGAAGCCTC
TGTTCAAAAATCTGGTCTCAGGCCAGTATGTCACCTTCAGTGATGCTGATAGTCATTGGTTTGCAGTGTCACAAACAGAA
ATAGATGGTGAAAATAAACTGTTCACTATTATTGATATTCAACAAATCGTCCAAACATACAAGCGAGATATCCAGTTGAT
TATTGCTGGATTTAGTGGTTTTTCATGCGTGATGCTAATTGGACTATATTGGGTTCTAAGCAAAGAACTCTCAGGTGTTA
GACAGATCAGAGAATGGATTCTTTCCCTTTCTGATGGTCAGATAAAAGAACGCAGGCCTATAAAATTCCATAACGAGCTC
GACACTATTGCCCAAAGTCTTGAAAATTTACAATTTAGGCTTCTTGATGTGGTGAGAAATTCTCATCGGACTATGAATGA
TTTAAGTATCAAACAGACTGACATTACGTATTCAATTGAAGGGAATACGAATAATTCACAGCAAGAACTTGGGCTCATTG
AACAAGTGGCCACAGCAACAACGCAACTATCATGTACTTCTTTTGATGTAATGCAACAAGCTCAAAGTGCAGAGCTTAAT
GCGGAGACGGCCCAAAAATTGATTGCTGAAAGTCATGATATTATCGATTCATCAAGCAAACAAACCGAAATGGTAACCCT
ATCGATCCATGAATCCCAACAAATAATCAATCAGTTACGCGAGTTTTCCGATAATATTAGTTCGGTTACGGATGTCATTA
ATAATATATCAGATCAAACTAACTTACTTGCCCTAAATGCAGCTATCGAGGCTGCTCGTGCAGGTGAACAGGGGCGCGGA
TTTGCTGTAGTAGCGGATGAAGTTCGTTCTCTTGCAGTGAAAACTCAGCAATCGACTATAGATATTCAAGGTATTATTTT
GAAACTGCAAGAGCAATCGCAGTTGGCAGATCAAGTGATGACACGTAATGTTTCACTTATTCATGAAACACAAGTTGCCA
ATCGGGCACTTATCGCATCCTTTAACCTGATTTCTGATAAGGTTCTTGAAATATCAAACATAAACTCCATCGTTTCGACT
GCCGCAAATGAACAAAAAATAGTAACTGAAGATGTAGCAAAACAGATGGAAGATATTCGATATCTAGTTCAAGAGAATTT
ATCCGCGATGGAACGAACTAAACAGGCAAATCAGAATATCTCTGATTTGACCACCAATCTAAATGATGCTCTTAGCTTTT
TTAAAATTGAGCTTACTTCATAA

Protein sequence :
MIKKIISVFLLLACIITSAFTAFFYHSKLSDQTKSISSLSSQQAQERLQSYQDSLDFYKKLNISLSVAIANSLRDKAVEE
LNAIALRIQENHGFIGVTFASLDGTMFTDIGTLDWNAKTLRRDWFVKTVELGTKHYTAFDIDKTTGQHVLTIATPVYVGN
DIVGSVALDIAGDQIASPNGSGMFMMTDRNFNVFASDLTHSTLIGKDLTKEKPLFKNLVSGQYVTFSDADSHWFAVSQTE
IDGENKLFTIIDIQQIVQTYKRDIQLIIAGFSGFSCVMLIGLYWVLSKELSGVRQIREWILSLSDGQIKERRPIKFHNEL
DTIAQSLENLQFRLLDVVRNSHRTMNDLSIKQTDITYSIEGNTNNSQQELGLIEQVATATTQLSCTSFDVMQQAQSAELN
AETAQKLIAESHDIIDSSSKQTEMVTLSIHESQQIINQLREFSDNISSVTDVINNISDQTNLLALNAAIEAARAGEQGRG
FAVVADEVRSLAVKTQQSTIDIQGIILKLQEQSQLADQVMTRNVSLIHETQVANRALIASFNLISDKVLEISNINSIVST
AANEQKIVTEDVAKQMEDIRYLVQENLSAMERTKQANQNISDLTTNLNDALSFFKIELTS