PAI Gene Information


Name : tpx (VC0395_A0349)
Accession : YP_001216305.1
PAI name : VPI-1
PAI accession : NC_009457_P1
Strain : Vibrio cholerae IEC224
Virulence or Resistance: Not determined
Product : thiol peroxidase
Function : -
Note : antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein
Homologs in the searched genomes :   638 hits    ( 638 protein-level )  
Publication :
    -Feng,L., Reeves,P.R., Lan,R., Ren,Y., Gao,C., Zhou,Z., Ren,Y., Cheng,J., Wang,W., Wang,J., Qian,W., Li,D. and Wang,L., "A recalibrated molecular clock and independent origins for the cholera pandemic clones", PLoS ONE 3 (12), E4053 (2008) PUBMED 19115014.

    -Feng,L., Reeves,P.R., Lan,R., Ren,Y., Gao,C., Zhou,Z., Ren,Y., Cheng,J., Wang,W., Wang,J., Qian,W., Li,D. and Wang,L., "Direct Submission", Submitted (18-MAY-2007) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA.

    -Heidelberg,J., "Direct Submission", Submitted (16-MAR-2007) The Institute for Genomic Research, 9712 Medical Center Drive, Rockville, MD 20850, USA.


DNA sequence :
ATGACTGTTACATTTCAAAATAATCCTGTTTCTATTTCTGGCTCTTTTCCTAAAGTAGGTGATCGTTTGCCTAGTTTTAC
TCTTTGTGGTGCTGATTTGAACGATCTTAACAATGAAGATTTTAAAGGAAAAAAGATTGTAATGAGCATTTTTCCCAGTA
TCGATACTCCGGTTTGTTCTAAAAGTGTGAAAGTTCTTCAAAATGCACTTATGACTCGCAGTGATACAGTGCTTCTCTGT
GTTTCAGCAGATCTGCCTTTTGCTATGTCTCGCTTTTGTACAGAGCATGCAGTAGCTAATGTCACGAATGCATCGTTTTT
TCGTGAGCCTGCTTTTACTGAACGCTTCGGTGTAAATCTAAATGAAGGTGCTTTACGTGGGCTTGCTGCTAGAGCAGTGA
TTGTTGCAGATGAGTTCGGTGTAATTACCCACAGTGAATTAGTCAATGAAATCACCAATGAACCAGATTACGATCGTATT
TTGATGTCACTATAA

Protein sequence :
MTVTFQNNPVSISGSFPKVGDRLPSFTLCGADLNDLNNEDFKGKKIVMSIFPSIDTPVCSKSVKVLQNALMTRSDTVLLC
VSADLPFAMSRFCTEHAVANVTNASFFREPAFTERFGVNLNEGALRGLAARAVIVADEFGVITHSELVNEITNEPDYDRI
LMSL