Name : topB-2 (EF2312)
Accession : NP_815968.1
PAI name : Not named
PAI accession : NC_004668_R1
Strain : Enterococcus faecalis D32
Virulence or Resistance: Not determined
Product : DNA topoisomerase III
Function : -
Note : similar to GP:8100667, and GP:10176010; identified by sequence similarity
Homologs in the searched genomes : 63 hits ( 63 protein-level )
Publication :
-Aakra,A., Vebo,H., Snipen,L., Hirt,H., Aastveit,A., Kapur,V., Dunny,G., Murray,B.E. and Nes,I.F., "Transcriptional response of Enterococcus faecalis V583 to erythromycin", Antimicrob. Agents Chemother. 49 (6), 2246-2259 (2005) PUBMED 15917518 REMARK Erratum:[Antimicrob Agents Chemother. 2005 Sep;49(9):3989. Murray, Barbara [corrected to Murray, Barbara E]].
-Paulsen,I., Banerjei,L., Myers,G., Nelson,K., Seshadri,R., Read,T., Fouts,D., Eisen,J., Gill,S., Heidelberg,J., Tettelin,H., Dodson,R., Umayam,L., Brinkac,L., Beanan,M., Daugherty,S., DeBoy,R., Durkin,A., Kolonay,J., Madupu,R., Nelson,W., Vamathevan,J., T, "Direct Submission", Submitted (03-FEB-2003) The Institute for Genomic Research, 9712 Medical Center Dr, Rockville, MD 20850, USA.
-Paulsen,I., Banerjei,L., Myers,G.S.A., Nelson,K.E., Seshadri,R., Read,T.D., Fouts,D.E., Eisen,J.A., Gill,S.R., Heidelberg,J.F., Tettelin,H., Dodson,R.J., Umayam,L., Brinkac,L., Beanan,M., Daugherty,S., DeBoy,R.T., Durkin,S., Kolonay,J., Madupu,R., Nelson,, "Role of Mobile DNA in the Evolution of Vancomycin-Resistant Enterococcus faecalis", Science 299 (5615), 2071-2074 (2003) PUBMED 12663927.
-Paulsen,I., Banerjei,L., Myers,G.S.A., Nelson,K.E., Seshadri,R., Read,T.D., Fouts,D.E., Eisen,J.A., Gill,S.R., Heidelberg,J.F., Tettelin,H., Dodson,R.J., Umayam,L., Brinkac,L., Beanan,M., Daugherty,S., DeBoy,R.T., Durkin,S., Kolonay,J., Madupu,R., Nelson,, "Direct Submission", Submitted (30-MAR-2003) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA.
-Wecker,P., Klockow,C., Ellrott,A., Quast,C., Langhammer,P., Harder,J. and Glockner,F.O., "Transcriptional response of the model planctomycete Rhodopirellula baltica SH1(T) to changing environmental conditions", BMC Genomics 10, 410 (2009) PUBMED 19725962 REMARK Publication Status: Online-Only.
| DNA sequence : | |
ATGCAGTTAGTGATCGCGGAAAAACCGTCGGTCGGAATGGCGCTGTCTAAGGTATTAGGCGCGAAAAGCCGTGGCGATGG
TTACATGGAGGGCGGCGGCTGGCTGGTAAGCTGGTGCATCGGGCATCTGGTGGAACTTGCCCCCGCCGATGCCTATGACC
CCCGCTATTCCAAATGGAACTATGCCGACCTGCCGATTTTACCAAAACCTTGGCAGTTCCAGGTGCTGCCGGACACCAAA
AAACAGTTTGAAGTCTTAAAAACCCTGATACACCGGGCCGATGTCACCGCCTTAATCTGTGCAACAGACGCAGGACGCGA
GGGGGAACTCATTTTCCGCCTGACTTACCATCTGTGCGGCTGCACCAAACCCGTCAAGCGGCTGTGGATTTCCTCAATGG
AGGAAGCCGCAATCCAGAAAGGCTTCGACAACCTGCTGGACGGGAAGAACTACGACAATCTCTACGCCGCCGCTCTCTGC
CGCGCCAAGGCGGACTGGCTGATCGGCATCAACGGTACGCGCCTGTTTACCACACTGTACCAGGGCAAGTCCCTGAACGT
GGGCCGGGTGCAGACCCCGACGCTGGCACTGCTGGCAGAACGGGAAGCCGCTATTTCCGGCTTTCAGAAAGAGAAATTTT
ACACGGTGGAGTTGGAACTGGAGGGCTTTCGCGCCGCCAGTGAACGCTTTGCATCCAAAACGGACGCAGGCAGGCTGCGT
ACCGGCTGTGTGGGCAAGCCTGCAACGGTACAGACGGTTTCCCAAAAGGAGAAAACCGAGCGCCCGCCCAAGCTGTACGA
TTTGACTACCCTCCAACGGGAGGCCAACCGGCTGTTTGACTACACCGCCCAGCAGACGCTTGATTATCTGCAAGCCCTCT
ATGAAAAGCGGCTGGCGACCTACCCCCGCACGGACAGCCGGTACTTGACCGAGGATATGGCGGCGGGGCTTCCCGCGCTG
TGCCAGTCCGTCGCTGCGGCGCTGCCCTTTGCGGCAGATTTGTCCTTGCCGGTAAATGCCGCGCAGGTAATCGACAACAG
CAAAGTCACCGACCATCATGCCATCCTGCCCACGACAGAAGCGGCAAAAACCGACCTGTCCGCGCTGCCCTCCGGGGAGA
AAAACATCCTCTTTCTGGTTGCCGCCCGTCTGCTGTGCGCGGTAGGCGAACCCCATACCTATGCGGAAACCGCTGTCACA
CTGGAATGTGGCGGCGCTGTCTTTTCCGCAAAAGGCAAAACGGAAACCGCCGCAGGCTGGACGGCTATGGAGCAGGCTTT
CCATGCCACACTGAAAAAGAAACCGAAGCAGCCCGAACCCTCCCCGCCACTTCCTGCACTCACCAAGGGCCAGAAGCTGA
CCGCCGGGGGTGCATCCATCAAAGAGGGCGCGACCTCCCCACCGGCCCATTTTACCGAGGACACGCTTCTCTCCGCAATG
GAACACGCCAGTGCAAAGGAGTTTGCGAAACTGGAAGATGTGGAACACAAAGGACTTGGCACTCCGGCCACCCGTGCCGG
CGTGATTGAAAAGCTGGTGCGCTCCGGCTTTGTGGAACGGAAGAAAAAGCAGCTTTTCCCCACGGAAAAAGGCACGGAAC
TTATCAAGGTAATGCCTGATACGCTGAAATCCGTCAAGCTGACCGCTGAATGGGAGGAACGGCTGGGCGCGGTGGAGCGC
GGGGAACTCTCCCCGGAGGACTTTATGGCGGGCATTACCGCCATGCTCACCGAACTGGTAAAAAGCTATCAGGGCGTGAC
CGTGGCATCTGCCGCCCTGTCTGCATCCGGGCGCACGGTAATTGGTATCTGCCCCCGCTGCGGCAAAAACGTGGTGGAGG
GCAAAAAGAGCTTTTTCTGCGAGGGCTGGAACGCTGCGCCCGCCTGCGACTTTGCCCTGTGGAAGAACGACCGCTTTTTT
ACCAGCAAGCACAAGGAACTGACCCGCAAGGCTGCCGCCGCCCTGCTGAAAAAAGGGCGCGTTGCCATGACCGGCCTGTT
TTCCGAGAAAAAAGGCGTGCTCTATGATGCAATTGTTGTGATGGAGGACACCGGAGAGAAATTTGTTCGCTTTAAGCTGG
AATTTGACAATAACACACCTAAAAAGAAAGGAAACTGA
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| Protein sequence : | |
MQLVIAEKPSVGMALSKVLGAKSRGDGYMEGGGWLVSWCIGHLVELAPADAYDPRYSKWNYADLPILPKPWQFQVLPDTK
KQFEVLKTLIHRADVTALICATDAGREGELIFRLTYHLCGCTKPVKRLWISSMEEAAIQKGFDNLLDGKNYDNLYAAALC
RAKADWLIGINGTRLFTTLYQGKSLNVGRVQTPTLALLAEREAAISGFQKEKFYTVELELEGFRAASERFASKTDAGRLR
TGCVGKPATVQTVSQKEKTERPPKLYDLTTLQREANRLFDYTAQQTLDYLQALYEKRLATYPRTDSRYLTEDMAAGLPAL
CQSVAAALPFAADLSLPVNAAQVIDNSKVTDHHAILPTTEAAKTDLSALPSGEKNILFLVAARLLCAVGEPHTYAETAVT
LECGGAVFSAKGKTETAAGWTAMEQAFHATLKKKPKQPEPSPPLPALTKGQKLTAGGASIKEGATSPPAHFTEDTLLSAM
EHASAKEFAKLEDVEHKGLGTPATRAGVIEKLVRSGFVERKKKQLFPTEKGTELIKVMPDTLKSVKLTAEWEERLGAVER
GELSPEDFMAGITAMLTELVKSYQGVTVASAALSASGRTVIGICPRCGKNVVEGKKSFFCEGWNAAPACDFALWKNDRFF
TSKHKELTRKAAAALLKKGRVAMTGLFSEKKGVLYDAIVVMEDTGEKFVRFKLEFDNNTPKKKGN
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