PAI Gene Information


Name : topB (t4234)
Accession : NP_807836.1
PAI name : SPI-7
PAI accession : NC_004631_P3
Strain : Salmonella enterica RSK2980
Virulence or Resistance: Not determined
Product : DNA topoisomerase III
Function : -
Note : decatenates replicating daughter chromosomes
Homologs in the searched genomes :   246 hits    ( 246 protein-level )  
Publication :
    -Deng,W., Liou,S.-R., Plunkett,G. III, Mayhew,G.F., Rose,D.J., Burland,V., Kodoyianni,V., Schwartz,D.C. and Blattner,F.R., "Direct Submission", Submitted (25-SEP-2002) Laboratory of Genetics, University of Wisconsin - Madison, 445 Henry Mall, Madison, WI 53706, USA.

    -Deng,W., Liou,S.R., Plunkett,G. III, Mayhew,G.F., Rose,D.J., Burland,V., Kodoyianni,V., Schwartz,D.C. and Blattner,F.R., "Comparative genomics of Salmonella enterica serovar Typhi strains Ty2 and CT18", J. Bacteriol. 185 (7), 2330-2337 (2003) PUBMED 12644504.

    -Deng,W., Liou,S.R., Plunkett,G. III, Mayhew,G.F., Rose,D.J., Burland,V., Kodoyianni,V., Schwartz,D.C. and Blattner,F.R., "Direct Submission", Submitted (10-SEP-2004) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA.


DNA sequence :
ATGCGTCTGGTGTTGTGTGAAAAACCTTCTCAGGGCAGAGATATTGCGAAGTTTCTTGGCGCCACTCAAAGAGGCGAAGG
ATTCCTGAATGGTCCGGGAGTTACAGTCACCTGGGCTCGCGGCCATCTGCTGGAGACAGCTGAACCGGAAGTATATGGCG
AACAGTATGGTAAGCCATGGCGCACCGATGTGCTTCCTTTATTACCACAGCAGTGGAAACTGGTAGTCAAAGCGGATGCA
AAAGCCCAATTCGCGGTAATTAACCGTCTGCTTAAACAGGTAGATGAGGTGGTAATTGCCACGGATGCTGACCGGGAAGG
TGAAGTAATCGCCCGTGAGTTGCTGGATTACTGCAAGTTTCAGGGGCGTGTATTCCGGTTGTGGATGTCAGCTCTGGATG
ATGCCAGTATCCGGTCAGCGTTAGCTGATTTGTGGCCGTCTTCCCGAACTGAATCGCTTTATTATGCTGGCGTGGGCAGG
AGCAGGGCTGACTGGCTGATCGGTATGAATCTGACTCGCCTGTTTACACTCCTGGGGCGTGAAGCGGGTATCGGTAACGT
ACTTTCAGTTGGCCGGGTACAAACGCCAACGCTGGCGATAGTGGTAAAGCGTGATCGTGAAATTGATAACTTCGTGTCGA
AACCGTACTTCGAAGTTATTGCCACGATGGCCGTGAATGGCGTGTTGTTTCCATCCAAATGGGTACCGGCTGCACAGTAT
TGCGATGAAGAGAAGCGTTGTATCCAGTCGGGGGTAGCGGCACAGGTGGTTCAGTTGTGTCGGCAAACGCCAACGGCTGC
GATAATCAATTGCCAGATCGAGAGGAAAAAACAATCAGCGCCGCTGGCTTTCAGCCTGAGCACACTACAACAGGCCTGCT
CCCGACACTGGGGGATGCCAGCCCAGACGGTACTTGATATCGCCCAGAAGTTATATGAAACCCACAAACTGACGACCTAT
CCCAGAACTGACTGTGGTTATCTGCCGTTATCGATGCGAGAAGAAATCCCACAGGTACTGTCTGCTGTGGTCGGAACTGA
TCCGGCGCTACAGCCGGTGGTCGCGAGTCTGGACACTCAGTTTGTGTCACGTATCTGGAATGATAAAAAAATTACCGCTC
ATCACGGTATCATTCCGACAAAACATACTGGTGATCTGAGCAAACTCAGTGATGCTGAGCGCAATGTCTATCAGCTGGTC
AGGTTGCACTACCTGGCCCAGTTCCTGCCCCAGATGGAAATTGACGTGACTGAGGCCACATTTAATATTGGCGGTCAGCT
TTTCCGTACCCGTGGTAACGTTTTGGTGAAACCCGGCTGGAAATCTCTGTTTGGCAAAATGTCCGAAGATGATGAGGATA
ATACTGGTGAAACCACACTGCCCGCCATGCAGGCGGGCCAGGTCTGCCAGGTGCAGGGCGCTGAGCAGAAGGTACTGCAG
ACAAAACCGCCTGCTCCGTACAACGATGGAACTCTTATTGCCGCGATGACCAATGCGGCGGCGTTCGTTACTGACGCCGC
GCTGAAAAAGGTGCTCAAAGAGAATGCGGGGATAGGAACTGAAGCAACACGGGCCGGGATAATCGACACGCTGTTGAAGC
GTGGGTTTCTGGTGCGTGAGAAAAAGACGCTTAAGTCAACACCTCTTGGACGTAACCTGGTGGATGTGTTGCCAGGAACG
TTAACGAATCCCGGACTTACGGCACTGTGGGAACAGATGCTGGATGAGGTAGCTGCAGGCAGGGTGAGCCTGGATGACTT
TATGGCAAAGCAAAGTCAGTGGGTCAGTCAGCTGGTCGCTCAGGGGAGATCACAGCCACTGACTATGCAGGCGCCACCTT
CACCACCCTGTCCTGTATGTGGCGGCAAGACGTTGCAGCGCAATGGAAAGAGTGGCTTGTTCTGGGGCTGCCTGAAATAT
CCGGAGTGCAAAGGTATCGTGAACAATGGTAACAAGGGCCCCAGAGGACGCAGACGAAAACCTTCGCCAGCCTAG

Protein sequence :
MRLVLCEKPSQGRDIAKFLGATQRGEGFLNGPGVTVTWARGHLLETAEPEVYGEQYGKPWRTDVLPLLPQQWKLVVKADA
KAQFAVINRLLKQVDEVVIATDADREGEVIARELLDYCKFQGRVFRLWMSALDDASIRSALADLWPSSRTESLYYAGVGR
SRADWLIGMNLTRLFTLLGREAGIGNVLSVGRVQTPTLAIVVKRDREIDNFVSKPYFEVIATMAVNGVLFPSKWVPAAQY
CDEEKRCIQSGVAAQVVQLCRQTPTAAIINCQIERKKQSAPLAFSLSTLQQACSRHWGMPAQTVLDIAQKLYETHKLTTY
PRTDCGYLPLSMREEIPQVLSAVVGTDPALQPVVASLDTQFVSRIWNDKKITAHHGIIPTKHTGDLSKLSDAERNVYQLV
RLHYLAQFLPQMEIDVTEATFNIGGQLFRTRGNVLVKPGWKSLFGKMSEDDEDNTGETTLPAMQAGQVCQVQGAEQKVLQ
TKPPAPYNDGTLIAAMTNAAAFVTDAALKKVLKENAGIGTEATRAGIIDTLLKRGFLVREKKTLKSTPLGRNLVDVLPGT
LTNPGLTALWEQMLDEVAAGRVSLDDFMAKQSQWVSQLVAQGRSQPLTMQAPPSPPCPVCGGKTLQRNGKSGLFWGCLKY
PECKGIVNNGNKGPRGRRRKPSPA