PAI Gene Information


Name : sea (MW1889)
Accession : NP_646706.1
PAI name : phi_Sa3
PAI accession : NC_003923_P6
Strain : Staphylococcus aureus 04-02981
Virulence or Resistance: Virulence
Product : enterotoxin A precursor
Function : -
Note : -
Homologs in the searched genomes :   67 hits    ( 67 protein-level )  
Publication :
    -Aoki,K., Oguchi,A., Nagai,Y., Asano,K., Iwama,N., Baba,T., Kuroda,M., Hiramatsu,K. and Kikuchi,H., "Direct Submission", Submitted (06-MAR-2002) Biotechnology Center, National Institute of Technology and Evaluation, 2Chome 49-10 Nishihara, Shibuya-ku, Tokyo 151-0066, Japan.

    -Baba,T., Takeuchi,F., Kuroda,M., Yuzawa,H., Aoki,K., Oguchi,A., Nagai,Y., Iwama,N., Asano,K., Naimi,T., Kuroda,H., Cui,L., Yamamoto,K. and Hiramatsu,K., "Genome and virulence determinants of high virulence community-acquired MRSA", Lancet 359 (9320), 1819-1827 (2002) PUBMED 12044378.

    -Baba,T., Takeuchi,F., Kuroda,M., Yuzawa,H., Aoki,K., Oguchi,A., Nagai,Y., Iwama,N., Asano,K., Naimi,T., Kuroda,H., Cui,L., Yamamoto,K. and Hiramatsu,K., "Direct Submission", Submitted (31-MAY-2002) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA.

    -Voyich,J.M., Vuong,C., DeWald,M., Nygaard,T.K., Kocianova,S., Griffith,S., Jones,J., Iverson,C., Sturdevant,D.E., Braughton,K.R., Whitney,A.R., Otto,M. and DeLeo,F.R., "The SaeR/S gene regulatory system is essential for innate immune evasion by Staphylococcus aureus", J. Infect. Dis. 199 (11), 1698-1706 (2009) PUBMED 19374556.


DNA sequence : 
ATGAAAAAAACAGCATTTACATTACTTTTATTCATTGCCCTAACGTTGACAACAAGTCCACTTGTAAATGGTAGCGAGAA
AAGCGAAGAAATAAATGAAAAAGATTTGCGAAAAAAGTCTGAATTGCAGGGAACAGCTTTAGGCAATCTTAAACAAATCT
ATTATTACAATGAAAAAGCTAAAACTGAAAATAAAGAGAGTCACGATCAATTTTTACAGCATACTATATTGTTTAAAGGC
TTTTTTACAGATCATTCGTGGTATAACGATTTATTAGTAGATTTTGATTCAAAGGATATTGTTGATAAATATAAAGGGAA
AAAAGTAGACTTGTATGGTGCTTATTATGGTTATCAATGTGCGGGTGGTACACCAAACAAAACAGCTTGTATGTATGGTG
GTGTAACGTTACATGATAATAATCGATTGACCGAAGAGAAAAAAGTGCCGATCAATTTATGGCTAGACGGTAAACAAAAT
ACAGTACCTTTGGAAACGGTTAAAACGAATAAGAAAAATGTAACTGTTCAGGAGTTGGATCTTCAAGCAAGACGTTATTT
ACAGGAAAAATATAATTTATATAACTCTGATGTTTTTGATGGGAAGGTTCAGAGGGGATTAATCGTGTTTCATACTTCTA
CAGAACCTTCGGTTAATTACGATTTATTTGGTGCTCAAGGACAGTATTCAAATACACTATTAAGAATATATAGAGATAAT
AAAACGATTAACTCTGAAAACATGCATATTGATATATATTTATATACAAGTTAA

Protein sequence : 
MKKTAFTLLLFIALTLTTSPLVNGSEKSEEINEKDLRKKSELQGTALGNLKQIYYYNEKAKTENKESHDQFLQHTILFKG
FFTDHSWYNDLLVDFDSKDIVDKYKGKKVDLYGAYYGYQCAGGTPNKTACMYGGVTLHDNNRLTEEKKVPINLWLDGKQN
TVPLETVKTNKKNVTVQELDLQARRYLQEKYNLYNSDVFDGKVQRGLIVFHTSTEPSVNYDLFGAQGQYSNTLLRIYRDN
KTINSENMHIDIYLYTS