Name : sptP (STM2878)
Accession : NP_461799.1
PAI name :
PAI accession : NC_003197_P3
Strain :
Virulence or Resistance: Virulence
Product : protein tyrosine phosphatase/GTPase activating protein
Function : -
Note : protein tyrosine phosphatase SptP (gi|1519054); translocated protein; type III secretion; antagonizes bacterial-encoded exchange factors SopE and SopE2 by interfering with stimulation of Cdc42 and Rac1; binds Rac1
Homologs in the searched genomes : 37 hits ( 33 protein-level, 4 DNA-level )
Publication :
-McClelland,M., Sanderson,K.E., Spieth,J., Clifton,S.W., Latreille,P., Courtney,L., Porwollik,S., Ali,J., Dante,M., Du,F., Hou,S., Layman,D., Leonard,S., Nguyen,C., Scott,K., Holmes,A., Grewal,N., Mulvaney,E., Ryan,E., Sun,H., Florea,L., Miller,W., Stoneki, "Complete genome sequence of Salmonella enterica serovar Typhimurium LT2", Nature 413 (6858), 852-856 (2001) PUBMED 11677609.
-McClelland,M., Sanderson,K.E., Spieth,J., Clifton,S.W., Latreille,P., Courtney,L., Porwollik,S., Ali,J., Dante,M., Du,F., Hou,S., Layman,D., Leonard,S., Nguyen,C., Scott,K., Holmes,A., Grewal,N., Mulvaney,E., Ryan,E., Sun,H., Florea,L., Miller,W., Stoneki, "Direct Submission", Submitted (10-SEP-2004) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA.
-McClelland,M., Sanderson,K.E., Spieth,J., Clifton,S.W., Latreille,P., Courtney,L., Porwollik,S., Ali,J., Dante,M., Du,F., Hou,S., Layman,D., Leonard,S., Nguyen,C., Scott,K., Holmes,A., Grewal,N., Mulvaney,E., Ryan,E., Sun,H., Florea,L., Miller,W., Stoneki, "Direct Submission", Submitted (06-NOV-2001) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA.
| DNA sequence : | |
ATGCTAAAGTATGAGGAGAGAAAATTGAATAATTTAACGTTGTCTTCGTTTTCAAAAGTTGGTGTGTCGAATGATGCCCG
ACTTTATATTGCTAAGGAAAATACTGATAAGGCATATGTTGCGCCTGAAAAATTTTCGTCAAAAGTATTAACCTGGCTTG
GAAAAATGCCGTTATTTAAAAACACTGAAGTGGTGCAAAAACATACGGAAAATATCAGAGTACAGGACCAAAAGATTTTA
CAGACATTTCTCCATGCACTAACGGAAAAATATGGGGAAACAGCGGTTAATGACGCACTGTTAATGTCCCGTATAAATAT
GAACAAACCCCTTACCCAACGTTTAGCAGTGCAGATCACGGAGTGTGTAAAAGCTGCTGACGAAGGGTTTATAAACCTTA
TTAAGAGCAAGGATAATGTTGGTGTCAGGAATGCCGCTTTAGTCATAAAAGGCGGCGATACAAAAGTGGCAGAAAAAAAT
AACGATGTTGGAGCAGAAAGTAAGCAACCTTTACTCGATATCGCGCTAAAGGGACTTAAAAGAACATTACCGCAACTGGA
ACAAATGGATGGAAATAGCCTGCGAGAAAACTTCCAGGAGATGGCTTCAGGTAACGGCCCGCTGCGTTCATTAATGACGA
ATTTACAGAATTTAAATAAAATTCCAGAGGCTAAACAACTTAATGATTATGTTACAACGTTAACAAATATTCAGGTCGGT
GTAGCCCGGTTCTCACAATGGGGAACCTGTGGAGGAGAGGTTGAGAGGTGGGTTGATAAAGCCTCTACTCATGAATTAAC
CCAGGCTGTAAAAAAAATTCACGTTATTGCTAAAGAACTGAAAAATGTTACAGCTGAACTTGAGAAAATAGAAGCCGGCG
CGCCAATGCCACAGACGATGAGCGGACCGACACTGGGCCTGGCACGATTTGCGGTCAGCAGCATTCCAATTAATCAGCAA
ACCCAGGTGAAACTGAGCGATGGAATGCCTGTGCCAGTGAATACGTTAACTTTTGACGGTAAGCCTGTGGCATTAGCCGG
TTCGTACCCAAAAAATACGCCGGATGCGCTGGAAGCGCATATGAAAATGCTTCTTGAAAAAGAATGCTCGTGCCTGGTGG
TGTTAACGTCGGAAGATCAGATGCAGGCAAAACAATTACCACCCTATTTCAGAGGGAGCTACACCTTTGGCGAGGTGCAT
ACCAACAGCCAAAAAGTGAGCTCAGCCAGTCAGGGAGAAGCGATAGACCAATACAATATGCAACTGTCCTGCGGGGAAAA
GCGGTATACAATCCCGGTATTGCATGTGAAAAATTGGCCAGATCACCAGCCGTTACCGTCTACGGATCAGTTAGAATACC
TGGCGGATAGGGTGAAAAATAGTAACCAAAATGGCGCGCCGGGGCGTAGTTCATCAGATAAGCATTTACCGATGATTCAT
TGTCTGGGCGGAGTGGGAAGAACCGGAACGATGGCGGCGGCCCTTGTACTTAAGGATAATCCTCATAGTAATCTGGAGCA
GGTACGTGCAGATTTCCGGGATTCACGGAACAATAGAATGCTGGAAGACGCCTCACAGTTTGTACAACTAAAAGCAATGC
AAGCCCAGTTGCTTATGACGACGGCAAGCTGA
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| Protein sequence : | |
MLKYEERKLNNLTLSSFSKVGVSNDARLYIAKENTDKAYVAPEKFSSKVLTWLGKMPLFKNTEVVQKHTENIRVQDQKIL
QTFLHALTEKYGETAVNDALLMSRINMNKPLTQRLAVQITECVKAADEGFINLIKSKDNVGVRNAALVIKGGDTKVAEKN
NDVGAESKQPLLDIALKGLKRTLPQLEQMDGNSLRENFQEMASGNGPLRSLMTNLQNLNKIPEAKQLNDYVTTLTNIQVG
VARFSQWGTCGGEVERWVDKASTHELTQAVKKIHVIAKELKNVTAELEKIEAGAPMPQTMSGPTLGLARFAVSSIPINQQ
TQVKLSDGMPVPVNTLTFDGKPVALAGSYPKNTPDALEAHMKMLLEKECSCLVVLTSEDQMQAKQLPPYFRGSYTFGEVH
TNSQKVSSASQGEAIDQYNMQLSCGEKRYTIPVLHVKNWPDHQPLPSTDQLEYLADRVKNSNQNGAPGRSSSDKHLPMIH
CLGGVGRTGTMAAALVLKDNPHSNLEQVRADFRDSRNNRMLEDASQFVQLKAMQAQLLMTTAS
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