PAI Gene Information


Name : tviB
Accession : NP_458740.1
PAI name : SPI-7
PAI accession : NC_003198_P9
Strain : Salmonella enterica RSK2980
Virulence or Resistance: Virulence
Product : Vi polysaccharide biosynthesis protein, UDP-glucose/GDP-mannose dehydrogenase
Function : -
Note : Similar to Salmonella typhi Vi polysaccharide biosynthesis protein VipA or TviB SW:VIPA_SALTI (Q04972) (425 aa) fasta scores: E(): 0, 99.8% id in 425 aa, and to Pseudomonas aeruginosa WbpO TR:Q9RHD7 (EMBL:AF035937) (422 aa) fasta scores: E(): 0, 66.8% id
Homologs in the searched genomes :   420 hits    ( 420 protein-level )  
Publication :
    -Parkhill,J., "Direct Submission", Submitted (25-OCT-2001) Submitted on behalf of the Salmonalla sequencing team, Sanger Centre, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK.

    -Parkhill,J., Dougan,G., James,K.D., Thomson,N.R., Pickard,D., Wain,J., Churcher,C., Mungall,K.L., Bentley,S.D., Holden,M.T., Sebaihia,M., Baker,S., Basham,D., Brooks,K., Chillingworth,T., Connerton,P., Cronin,A., Davis,P., Davies,R.M., Dowd,L., White,N., , "Complete genome sequence of a multiple drug resistant Salmonella enterica serovar Typhi CT18", Nature 413 (6858), 848-852 (2001) PUBMED 11677608.

    -Parkhill,J., Dougan,G., James,K.D., Thomson,N.R., Pickard,D., Wain,J., Churcher,C., Mungall,K.L., Bentley,S.D., Holden,M.T., Sebaihia,M., Baker,S., Basham,D., Brooks,K., Chillingworth,T., Connerton,P., Cronin,A., Davis,P., Davies,R.M., Dowd,L., White,N., , "Direct Submission", Submitted (10-SEP-2013) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA.


DNA sequence :
GTGTTCGGTATAGACGAGGTAAAAATCGCGATTATTGGGCTGGGATATGTTGGGCTTCCTCTGGCAGTTGAATTTGGCAA
ATCTCGTCAGGTTGTTGGCTTCGACGTTAATAAAAAGCGTATTCTTGAATTAAAGAATGGGGTGGATGTCAATCTGGAAA
CCACTGAAGAAGAATTACGTGAGGCTCGTTATCTGAAATTTACTTCCGAGATTGAGAAGATCAAAGAATGTAATTTTTAC
ATCATCACCGTCCCGACGCCGATAAATACCTACAAGCAACCAGACCTCACCCCACTAATCAAGGCGAGTGAAACCGTTGG
TACAGTGCTGAATCGGGGAGATATTGTGGTATATGAATCTACGGTATATCCGGGATGTACCGAAGAAGAATGCGTGCCGA
TCCTTGCTCGTATGTCCGGAATGACTTTCAACCAGGATTTCTATGTCGGTTATAGCCCGGAAAGGATCAATCCCGGTGAT
AAAAAGCACCGTTTAACCAACATCAAGAAAATCACCTCCGGTTCAACCGCACAGATCGCCGAACTTATCGATGAAGTATA
TCAGCAGATCATCAGCGCAGGTACATATAAAGCAGAGAGCATCAAAGTTGCTGAGGCAGCGAAGGTGATTGAAAATACGC
AACGCGATCTGAATATTGCCTTGGTCAATGAGCTGGCGATTATTTTTAATCGTTTAAATATCGATACTGAAGCCGTGCTA
CGTGCCGCTGGCAGCAAATGGAATTTCCTGCCATTCCGTCCGGGACTGGTCGGTGGTCACTGTATTGGCGTAGATCCCTA
TTATCTGACACATAAATCTCAGGGCATTGGCTATTATCCAGAAATCATACTTGCAGGACGCCGCCTGAACGACAACATGG
GCAACTATGTCTCCGAGCAGTTGATCAAAGCAATGATCAAAAAAGGAATTAACGTTGAGGGTTCCAGCGTGCTGATTCTC
GGCTTTACCTTTAAAGAAAACTGTCCGGACATCAGAAATACACGCATTATTGATGTGGTAAAGGAACTCGGTAAATATAG
TTGTAAAGTGGATATTTTTGATCCATGGGTGGATGCCGAAGAGGTAAGACGAGAGTATGGCATTATCCCGGTATCGGAAG
TCAAATCAAGCCACTACGATGCGATCATTGTTGCAGTAGGACATCAGCAATTTAAACAGATGGGAAGTGAGGATATTCGC
GGCTTCGGAAAAGATAAACATGTACTTTATGATTTGAAGTATGTTCTTCCGGCTGAGCAGTCAGATGTGAGATTGTAA

Protein sequence :
MFGIDEVKIAIIGLGYVGLPLAVEFGKSRQVVGFDVNKKRILELKNGVDVNLETTEEELREARYLKFTSEIEKIKECNFY
IITVPTPINTYKQPDLTPLIKASETVGTVLNRGDIVVYESTVYPGCTEEECVPILARMSGMTFNQDFYVGYSPERINPGD
KKHRLTNIKKITSGSTAQIAELIDEVYQQIISAGTYKAESIKVAEAAKVIENTQRDLNIALVNELAIIFNRLNIDTEAVL
RAAGSKWNFLPFRPGLVGGHCIGVDPYYLTHKSQGIGYYPEIILAGRRLNDNMGNYVSEQLIKAMIKKGINVEGSSVLIL
GFTFKENCPDIRNTRIIDVVKELGKYSCKVDIFDPWVDAEEVRREYGIIPVSEVKSSHYDAIIVAVGHQQFKQMGSEDIR
GFGKDKHVLYDLKYVLPAEQSDVRL