Name : topB
Accession : NP_458624.1
PAI name : SPI-7
PAI accession : NC_003198_P9
Strain : Salmonella enterica RSK2980
Virulence or Resistance: Not determined
Product : topoisomerase B
Function : -
Note : Previously sequenced Salmonella typhi topoisomerase B TopB TR:Q9RHF5 (EMBL:AF000001) (664 aa) fasta scores: E(): 0, 100.0% id in 664 aa. Also similar to Escherichia coli DNA topoisomerase III TopB SW:TOP3_ECOLI (P14294) (653 aa) fasta scores: E(): 0, 40.7
Homologs in the searched genomes : 246 hits ( 246 protein-level )
Publication :
-Parkhill,J., "Direct Submission", Submitted (25-OCT-2001) Submitted on behalf of the Salmonalla sequencing team, Sanger Centre, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK.
-Parkhill,J., Dougan,G., James,K.D., Thomson,N.R., Pickard,D., Wain,J., Churcher,C., Mungall,K.L., Bentley,S.D., Holden,M.T., Sebaihia,M., Baker,S., Basham,D., Brooks,K., Chillingworth,T., Connerton,P., Cronin,A., Davis,P., Davies,R.M., Dowd,L., White,N., , "Complete genome sequence of a multiple drug resistant Salmonella enterica serovar Typhi CT18", Nature 413 (6858), 848-852 (2001) PUBMED 11677608.
-Parkhill,J., Dougan,G., James,K.D., Thomson,N.R., Pickard,D., Wain,J., Churcher,C., Mungall,K.L., Bentley,S.D., Holden,M.T., Sebaihia,M., Baker,S., Basham,D., Brooks,K., Chillingworth,T., Connerton,P., Cronin,A., Davis,P., Davies,R.M., Dowd,L., White,N., , "Direct Submission", Submitted (10-SEP-2013) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA.
| DNA sequence : | |
ATGCGTCTGGTGTTGTGTGAAAAACCTTCTCAGGGCAGAGATATTGCGAAGTTTCTTGGCGCCACTCAAAGAGGCGAAGG
ATTCCTGAATGGTCCGGGAGTTACAGTCACCTGGGCTCGCGGCCATCTGCTGGAGACAGCTGAACCGGAAGTATATGGCG
AACAGTATGGTAAGCCATGGCGCACCGATGTGCTTCCTTTATTACCACAGCAGTGGAAACTGGTAGTCAAAGCGGATGCA
AAAGCCCAATTCGCGGTAATTAACCGTCTGCTTAAACAGGTAGATGAGGTGGTAATTGCCACGGATGCTGACCGGGAAGG
TGAAGTAATCGCCCGTGAGTTGCTGGATTACTGCAAGTTTCAGGGGCGTGTATTCCGGTTGTGGATGTCAGCTCTGGATG
ATGCCAGTATCCGGTCAGCGTTAGCTGATTTGTGGCCGTCTTCCCGAACTGAATCGCTTTATTATGCTGGCGTGGGCAGG
AGCAGGGCTGACTGGCTGATCGGTATGAATCTGACTCGCCTGTTTACACTCCTGGGGCGTGAAGCGGGTATCGGTAACGT
ACTTTCAGTTGGCCGGGTACAAACGCCAACGCTGGCGATAGTGGTAAAGCGTGATCGTGAAATTGATAACTTCGTGTCGA
AACCGTACTTCGAAGTTATTGCCACGATGGCCGTGAATGGCGTGTTGTTTCCATCCAAATGGGTACCGGCTGCACAGTAT
TGCGATGAAGAGAAGCGTTGTATCCAGTCGGGGGTAGCGGCACAGGTGGTTCAGTTGTGTCGGCAAACGCCAACGGCTGC
GATAATCAATTGCCAGATCGAGAGGAAAAAACAATCAGCGCCGCTGGCTTTCAGCCTGAGCACACTACAACAGGCCTGCT
CCCGACACTGGGGGATGCCAGCCCAGACGGTACTTGATATCGCCCAGAAGTTATATGAAACCCACAAACTGACGACCTAT
CCCAGAACTGACTGTGGTTATCTGCCGTTATCGATGCGAGAAGAAATCCCACAGGTACTGTCTGCTGTGGTCGGAACTGA
TCCGGCGCTACAGCCGGTGGTCGCGAGTCTGGACACTCAGTTTGTGTCACGTATCTGGAATGATAAAAAAATTACCGCTC
ATCACGGTATCATTCCGACAAAACATACTGGTGATCTGAGCAAACTCAGTGATGCTGAGCGCAATGTCTATCAGCTGGTC
AGGTTGCACTACCTGGCCCAGTTCCTGCCCCAGATGGAAATTGACGTGACTGAGGCCACATTTAATATTGGCGGTCAGCT
TTTCCGTACCCGTGGTAACGTTTTGGTGAAACCCGGCTGGAAATCTCTGTTTGGCAAAATGTCCGAAGATGATGAGGATA
ATACTGGTGAAACCACACTGCCCGCCATGCAGGCGGGCCAGGTCTGCCAGGTGCAGGGCGCTGAGCAGAAGGTACTGCAG
ACAAAACCGCCTGCTCCGTACAACGATGGAACTCTTATTGCCGCGATGACCAATGCGGCGGCGTTCGTTACTGACGCCGC
GCTGAAAAAGGTGCTCAAAGAGAATGCGGGGATAGGAACTGAAGCAACACGGGCCGGGATAATCGACACGCTGTTGAAGC
GTGGGTTTCTGGTGCGTGAGAAAAAGACGCTTAAGTCAACACCTCTTGGACGTAACCTGGTGGATGTGTTGCCAGGAACG
TTAACGAATCCCGGACTTACGGCACTGTGGGAACAGATGCTGGATGAGGTAGCTGCAGGCAGGGTGAGCCTGGATGACTT
TATGGCAAAGCAAAGTCAGTGGGTCAGTCAGCTGGTCGCTCAGGGGAGATCACAGCCACTGACTATGCAGGCGCCACCTT
CACCACCCTGTCCTGTATGTGGCGGCAAGACGTTGCAGCGCAATGGAAAGAGTGGCTTGTTCTGGGGCTGCCTGAAATAT
CCGGAGTGCAAAGGTATCGTGAACAATGGTAACAAGGGCCCCAGAGGACGCAGACGAAAACCTTCGCCAGCCTAG
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| Protein sequence : | |
MRLVLCEKPSQGRDIAKFLGATQRGEGFLNGPGVTVTWARGHLLETAEPEVYGEQYGKPWRTDVLPLLPQQWKLVVKADA
KAQFAVINRLLKQVDEVVIATDADREGEVIARELLDYCKFQGRVFRLWMSALDDASIRSALADLWPSSRTESLYYAGVGR
SRADWLIGMNLTRLFTLLGREAGIGNVLSVGRVQTPTLAIVVKRDREIDNFVSKPYFEVIATMAVNGVLFPSKWVPAAQY
CDEEKRCIQSGVAAQVVQLCRQTPTAAIINCQIERKKQSAPLAFSLSTLQQACSRHWGMPAQTVLDIAQKLYETHKLTTY
PRTDCGYLPLSMREEIPQVLSAVVGTDPALQPVVASLDTQFVSRIWNDKKITAHHGIIPTKHTGDLSKLSDAERNVYQLV
RLHYLAQFLPQMEIDVTEATFNIGGQLFRTRGNVLVKPGWKSLFGKMSEDDEDNTGETTLPAMQAGQVCQVQGAEQKVLQ
TKPPAPYNDGTLIAAMTNAAAFVTDAALKKVLKENAGIGTEATRAGIIDTLLKRGFLVREKKTLKSTPLGRNLVDVLPGT
LTNPGLTALWEQMLDEVAAGRVSLDDFMAKQSQWVSQLVAQGRSQPLTMQAPPSPPCPVCGGKTLQRNGKSGLFWGCLKY
PECKGIVNNGNKGPRGRRRKPSPA
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