PAI Gene Information


Name : STY4456
Accession : NP_458556.1
PAI name : SPI-4
PAI accession : NC_003198_P8
Strain : Salmonella enterica RSK2980
Virulence or Resistance: Not determined
Product : putative type-I secretion protein
Function : -
Note : Similar to several putative type I membrane transport proteins including: Vibrio cholerae outer membrane protein TolC TR:Q9K2Y1 (EMBL:AE004313) (438 aa) fasta scores: E(): 2.2e-12, 20.4% id in 442 aa, Neisseria meningitidis putative periplasmic type I sec
Homologs in the searched genomes :   40 hits    ( 40 protein-level )  
Publication :
    -Parkhill,J., "Direct Submission", Submitted (25-OCT-2001) Submitted on behalf of the Salmonalla sequencing team, Sanger Centre, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK.

    -Parkhill,J., Dougan,G., James,K.D., Thomson,N.R., Pickard,D., Wain,J., Churcher,C., Mungall,K.L., Bentley,S.D., Holden,M.T., Sebaihia,M., Baker,S., Basham,D., Brooks,K., Chillingworth,T., Connerton,P., Cronin,A., Davis,P., Davies,R.M., Dowd,L., White,N., , "Complete genome sequence of a multiple drug resistant Salmonella enterica serovar Typhi CT18", Nature 413 (6858), 848-852 (2001) PUBMED 11677608.

    -Parkhill,J., Dougan,G., James,K.D., Thomson,N.R., Pickard,D., Wain,J., Churcher,C., Mungall,K.L., Bentley,S.D., Holden,M.T., Sebaihia,M., Baker,S., Basham,D., Brooks,K., Chillingworth,T., Connerton,P., Cronin,A., Davis,P., Davies,R.M., Dowd,L., White,N., , "Direct Submission", Submitted (10-SEP-2013) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA.


DNA sequence :
ATGAAGATTAAGATGTTTTTTCTGACGACTGCTTTTATTACACAAAGCACATACGCCAGCGAGCTTCCGGTCATTCCTCT
AAGAGATTTAGTTAATGCCGCATTAACGCATCAGCCCTCTGTTGCTGTTTCATATTATGAGACTGAAAAGAAAAACAGTG
ACTTAGATCTTTCACGGGCAGCACTTTATCCTACCCTGGATCTAACCTCTGGCCTTAATAATAACAGAAAGGAGTCGTCA
GGTACCGAGAGAAACGTTGAAAATAAGGTATCTTTATCATACCGAATAACGGATTTTGGAGTGAGGGGGGCTAATATCAG
GAAATCTGAATACGAAAGAGATAATAGTAAAACTGACTATGAAAAAACAAAGAATATAGTGTCTCAGGAGGTTGTGACAA
CCTATTACAACATCAGTAAATATCGTGAAATGATTGATGGCGTAAATCTGGAGAAAGAGTTTTATAAAAAGATGCTGGAA
ACTTTTTCGCTACTGGTATCTTCCGGTGTAGCTATGCAATCTGATATGCGTAAAGTACAAGTATCTATCGATGCATTAAA
TACCAGAAGTATTATGTATCAGTCGATGCTGGATGATGAAATGTATAAAATGCAGAATATGACTGGTCTGAATTTATCAC
CAGATCAGATTCAAAGCGATGAAAAATTCAACCTCTTCAAAAAATATATCTTTGTCGAAAGCCCTGAAAAACTTATGGAC
ATGGTGATGAAATACAACGATGACTATAAGATGCTTGTCAATACCCGAAAAGCTGCGACCGAAGATATTAATGCCGCAAA
ATCATCCTATTTTCCGACTGTAGATCTCGTTTCCAGCTATGTACAGAATAATCCGAGCGGTAGTGCCAAAAAAAGTGATT
ATGAAGATGAATTTAAAACGGGTATCAATGTCAGTTTCAACATTTTTAATGGGTTTAGAAATGCAGCCCAGGAAAGAAAA
ATGGTGGCAAGTTACTCGCAGGCTAAGCTGCAAATTGACGATTTCTTGATTAAAACTCGTTATAACATTGATTCACAACT
TTCAAAATACACCGCTGCAAAAGAGACTTACTCAGTGGCGGAACGTTCACATACAAACGCGTTACAGCTTACTGAATTAT
ATGAGCAGGAGTTTCAGTTAGGGCAAAAAAGTTTGCTTGATTTAATTTCAAGCCGTAATGAAGCATTTCAGGCATATGTA
AGCATGATCGACAGCAAATATAGCCTGTATATTTTAAAGCTACAGCAACTCTCATTGATTTTTCATTTAATGGATTATTT
AAAAAGTGAGTTAAATGTAATGAAATGA

Protein sequence :
MKIKMFFLTTAFITQSTYASELPVIPLRDLVNAALTHQPSVAVSYYETEKKNSDLDLSRAALYPTLDLTSGLNNNRKESS
GTERNVENKVSLSYRITDFGVRGANIRKSEYERDNSKTDYEKTKNIVSQEVVTTYYNISKYREMIDGVNLEKEFYKKMLE
TFSLLVSSGVAMQSDMRKVQVSIDALNTRSIMYQSMLDDEMYKMQNMTGLNLSPDQIQSDEKFNLFKKYIFVESPEKLMD
MVMKYNDDYKMLVNTRKAATEDINAAKSSYFPTVDLVSSYVQNNPSGSAKKSDYEDEFKTGINVSFNIFNGFRNAAQERK
MVASYSQAKLQIDDFLIKTRYNIDSQLSKYTAAKETYSVAERSHTNALQLTELYEQEFQLGQKSLLDLISSRNEAFQAYV
SMIDSKYSLYILKLQQLSLIFHLMDYLKSELNVMK