PAI Gene Information


Name : spaP
Accession : NP_457284.1
PAI name : SPI-1
PAI accession : NC_003198_P5
Strain : Salmonella enterica RSK2980
Virulence or Resistance: Virulence
Product : secretory protein (associated with virulence)
Function : -
Note : Previously sequenced Salmonella typhi surface presentation of antigens protein SpaP SW:SPAP_SALTI (Q56023) (224 aa) fasta scores: E(): 0, 100.0% id in 224 aa. Also similar to many others e.g. Shigella flexneri SW:SPAP_SHIFL (P35529) (216 aa) fasta scores:
Homologs in the searched genomes :   184 hits    ( 184 protein-level )  
Publication :
    -Parkhill,J., "Direct Submission", Submitted (25-OCT-2001) Submitted on behalf of the Salmonalla sequencing team, Sanger Centre, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK.

    -Parkhill,J., Dougan,G., James,K.D., Thomson,N.R., Pickard,D., Wain,J., Churcher,C., Mungall,K.L., Bentley,S.D., Holden,M.T., Sebaihia,M., Baker,S., Basham,D., Brooks,K., Chillingworth,T., Connerton,P., Cronin,A., Davis,P., Davies,R.M., Dowd,L., White,N., , "Complete genome sequence of a multiple drug resistant Salmonella enterica serovar Typhi CT18", Nature 413 (6858), 848-852 (2001) PUBMED 11677608.

    -Parkhill,J., Dougan,G., James,K.D., Thomson,N.R., Pickard,D., Wain,J., Churcher,C., Mungall,K.L., Bentley,S.D., Holden,M.T., Sebaihia,M., Baker,S., Basham,D., Brooks,K., Chillingworth,T., Connerton,P., Cronin,A., Davis,P., Davies,R.M., Dowd,L., White,N., , "Direct Submission", Submitted (10-SEP-2013) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA.


DNA sequence : 
ATGGGGAATGATATCTCATTAATTGCCTTACTGGCATTTTCCACCCTGTTGCCATTTATTATTGCGTCAGGAACCTGTTT
CGTTAAATTTTCTATTGTATTTGTCATGGTGCGTAACGCCCTGGGATTGCAGCAGATACCTTCAAATATGACGCTTAACA
GCGTCGCATTGCTGCTTTCTATGTTTGTTATGTGGCCAATAATGCATGATGCCTACGTCTATTTTGAGGACGAAGATGTC
ACCTTTAATGATATTTCGTCATTAAGTAAACACGTTGATGAAGGTCTGGATGGTTATCGCGATTATCTGATCAAATATTC
AGATCGCGAGTTAGTTCAGTTTTTTGAAAACGCGCAACTGAAGCGTCAGTATGGAGAAGAGACCGAGACGGTAAAGCGTG
ACAAAGATGAAATTGAAAAACCATCAATATTTGCGTTATTACCTGCTTATGCGCTGAGCGAAATAAAAAGCGCGTTTAAA
ATTGGTTTTTATCTCTATTTGCCCTTTGTTGTCGTCGACCTGGTGGTATCCAGCGTGCTACTGGCGCTGGGGATGATGAT
GATGAGTCCGGTGACGATATCTACACCTATTAAGCTGGTGCTTTTTGTCGCGCTTGATGGCTGGACCTTACTGTCTAAGG
GATTGATATTACAGTATATGGACATTGCAACATGA

Protein sequence : 
MGNDISLIALLAFSTLLPFIIASGTCFVKFSIVFVMVRNALGLQQIPSNMTLNSVALLLSMFVMWPIMHDAYVYFEDEDV
TFNDISSLSKHVDEGLDGYRDYLIKYSDRELVQFFENAQLKRQYGEETETVKRDKDEIEKPSIFALLPAYALSEIKSAFK
IGFYLYLPFVVVDLVVSSVLLALGMMMMSPVTISTPIKLVLFVALDGWTLLSKGLILQYMDIAT