PAI Gene Information


Name : sipA
Accession : NP_457276.1
PAI name : SPI-1
PAI accession : NC_003198_P5
Strain : Salmonella enterica RSK2980
Virulence or Resistance: Virulence
Product : pathogenicity island 1 effector protein (function unknown)
Function : -
Note : Previously partially sequenced Salmonella typhi SipA TR:P74849 (EMBL:X92546) (450 aa) fasta scores: E(): 0, 100.0% id in 450 aa. Also highly similar to Salmonella typhimurium SipA TR:Q56034 (EMBL:U40013) (684 aa) fasta scores: E(): 0, 95.5% id in 685 aa a
Homologs in the searched genomes :   41 hits    ( 41 protein-level )  
Publication :
    -Parkhill,J., "Direct Submission", Submitted (25-OCT-2001) Submitted on behalf of the Salmonalla sequencing team, Sanger Centre, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK.

    -Parkhill,J., Dougan,G., James,K.D., Thomson,N.R., Pickard,D., Wain,J., Churcher,C., Mungall,K.L., Bentley,S.D., Holden,M.T., Sebaihia,M., Baker,S., Basham,D., Brooks,K., Chillingworth,T., Connerton,P., Cronin,A., Davis,P., Davies,R.M., Dowd,L., White,N., , "Complete genome sequence of a multiple drug resistant Salmonella enterica serovar Typhi CT18", Nature 413 (6858), 848-852 (2001) PUBMED 11677608.

    -Parkhill,J., Dougan,G., James,K.D., Thomson,N.R., Pickard,D., Wain,J., Churcher,C., Mungall,K.L., Bentley,S.D., Holden,M.T., Sebaihia,M., Baker,S., Basham,D., Brooks,K., Chillingworth,T., Connerton,P., Cronin,A., Davis,P., Davies,R.M., Dowd,L., White,N., , "Direct Submission", Submitted (10-SEP-2013) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA.


DNA sequence :
ATGGTTACAAGTGTAAGAACTCAGCCCCCCGTCATAATGCCAGGTATGCAGACCGAGATCAAAACGCAGGCCACGAATCT
TGCGGCGAATCTTTCCGCGGTCAGAGAAAGTGCCACAGCAACGCTGTCAGGGGAAATTAAAGGCCAGCAACTGGAAGATT
TTCCCGCGCTGATCAAACAGGCGAGTCTGGATGCGTTGTTTAAATGCGGGAAAGACGCCGAGGCGTTAAAAGAAGTTTTT
ACCAATTCAAATAATGTCGCCGGTAAGAAAGCGATAATGGAGTTTGCCGGCCTCTTTCGTTCAGCGCTCAACGCCACCAG
TGATTCTCCTGAGGCGAAGACGCTACTGATGAAGGTGGGGGCAGAGTATACCGCGCAAATCATAAAAGATGGCCTGAAAG
AAAAGTCAGCTTTTGGGCCATGGCTGCCAGAAACAAAGAAAGCGGAAGCGAAGCTGGAAAACCTGGAAAAGCAGCTGTTA
GATATCATCAAAAATAACACTGGCGGTGAATTAAGTAAATTATCGACGAATCTTGTTATGCAGGAGGTGATGCCCTATAT
TGCCAGCTGCATTGAACATAACTTTGGCTGTACGTTAGATCCGTTAACCCGCAGCAGTCTTACGCAGCTTGTTGACAAAG
CGGCGGCGAAGGCGGTTGAGGCGCTTGATATGTGCCACCAAAAATTAACGCAAGAGCAGGGTACCAGCGTAGGACGGGAA
GCCCGGCACCTTGAAATGCAAACGTTGATACCCCTGCTGCTACGTAATGTTTTTGCACAAATTCCTGCAGATAAACTGCC
TGACCCTAAAATTCCGGAACCTGCGGCTGGACCAGTACCTGATGGTGGGAAAAAAGCAGAACCTACGGGTATTAATATCA
ATATTAATATTGATAGCAGTAACCATAGCGTGGATAACAGTAAGCATATTAACAATAGCCGAAGCCATGTCGATAATAGC
CAGCGCCATATCGATAATAGCAACCATGATAATAGCCGGAAGACGATTGATAATAGCCGAACATTTATTGATAACAGCCA
ACGCCATGGCGAGTCACACCATTCGACTAACAGCAGCAACGTAAGTCATAGTCATTCGCGTGTGGATTCGACTACGCATC
AAACGGAGACCGCACACAGCGCCAGCACAGGGACAATTGACCATGGCATCGCGGGTAAAATTGACGTCACGGCTCATGCG
ACGGCAGAGGCTGTGACCAACTCTTCATCCGAAAGTAAAGATGGAAAGGTGGTCACGTCAGAAAAGGGCACTACGGGTGA
AACAACCTCTTTTGATGAAGTCGATGGCGTAACCAGCAAGAGCATTATCGGCAAGCCGTTACAGGCCACGGTGCACGGCG
TTGATGATAATAAACAGCAAAGCCAGACGGCAGAGATTGTGAATGTGAAGCCGCTTGCCAGTCAACTGGCTGGCGTCGAG
AATGTTAAAATCGATACCTTACAATCAGACTCGACGGTAATTACAGGTAATAAAGCCGGTACGACCGATAATGATAATAG
CCAGACAGATAAGACTGGCCCATTTTCTGGTTTGAAGTTTAAGCAAAATAGTTTCCTCTCAACAGTACCGAGCGTTACGA
ATATGCATTCAATACATTTCAACGCCCGTGAGGCGTTTTTGGGTGTGATACGTAAAGCCCTGGAGCCGGATGCCTCTACA
CCGTTTCCTGTACGCAGAGCGTTTGACGGCTTGCGTGGGGAAATATTACCCAATGACACGATAAAGAGTGCAGCGTTGAA
AGCGCAATGTAGCGATATTGACAAGCACCCAGAATTGAAAGCGAAAATGGAGACGCTCAAAGAGGTCATTACTCATCATC
CACAAAAAGAAAAACTGGCTGAGATTGCATTGCAGTTTGCCAGAGAGGCGGGGTTGACCAGGCAAAAAGGGGAAACTGAC
TATGTGTTAAGTAATGTGCTGGACGGCCTTATCGGAGACGGTAGCTGGCGAGCTGGCCCGGCTTACGAGTCATACCTGAA
TAAACCTGGTGTGGATCGGGTTATTACTACCGTTGATGGCTTGCACATGCAGCGTTAA

Protein sequence :
MVTSVRTQPPVIMPGMQTEIKTQATNLAANLSAVRESATATLSGEIKGQQLEDFPALIKQASLDALFKCGKDAEALKEVF
TNSNNVAGKKAIMEFAGLFRSALNATSDSPEAKTLLMKVGAEYTAQIIKDGLKEKSAFGPWLPETKKAEAKLENLEKQLL
DIIKNNTGGELSKLSTNLVMQEVMPYIASCIEHNFGCTLDPLTRSSLTQLVDKAAAKAVEALDMCHQKLTQEQGTSVGRE
ARHLEMQTLIPLLLRNVFAQIPADKLPDPKIPEPAAGPVPDGGKKAEPTGINININIDSSNHSVDNSKHINNSRSHVDNS
QRHIDNSNHDNSRKTIDNSRTFIDNSQRHGESHHSTNSSNVSHSHSRVDSTTHQTETAHSASTGTIDHGIAGKIDVTAHA
TAEAVTNSSSESKDGKVVTSEKGTTGETTSFDEVDGVTSKSIIGKPLQATVHGVDDNKQQSQTAEIVNVKPLASQLAGVE
NVKIDTLQSDSTVITGNKAGTTDNDNSQTDKTGPFSGLKFKQNSFLSTVPSVTNMHSIHFNAREAFLGVIRKALEPDAST
PFPVRRAFDGLRGEILPNDTIKSAALKAQCSDIDKHPELKAKMETLKEVITHHPQKEKLAEIALQFAREAGLTRQKGETD
YVLSNVLDGLIGDGSWRAGPAYESYLNKPGVDRVITTVDGLHMQR