PAI Gene Information


Name : prgI
Accession : NP_457267.1
PAI name : SPI-1
PAI accession : NC_003198_P5
Strain : Salmonella enterica RSK2980
Virulence or Resistance: Virulence
Product : pathogenicity 1 island effector protein
Function : -
Note : Similar to several proteins essential for protein secretion by a type III system: Salmonella typhimurium protein PrgI required for invasion of epithelial cells SW:PRGI_SALTY (P41784) (80 aa) fasta scores: E(): 4.2e-28, 95.0% id in 80 aa and Shigella flexn
Homologs in the searched genomes :   82 hits    ( 82 protein-level )  
Publication :
    -Parkhill,J., "Direct Submission", Submitted (25-OCT-2001) Submitted on behalf of the Salmonalla sequencing team, Sanger Centre, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK.

    -Parkhill,J., Dougan,G., James,K.D., Thomson,N.R., Pickard,D., Wain,J., Churcher,C., Mungall,K.L., Bentley,S.D., Holden,M.T., Sebaihia,M., Baker,S., Basham,D., Brooks,K., Chillingworth,T., Connerton,P., Cronin,A., Davis,P., Davies,R.M., Dowd,L., White,N., , "Complete genome sequence of a multiple drug resistant Salmonella enterica serovar Typhi CT18", Nature 413 (6858), 848-852 (2001) PUBMED 11677608.

    -Parkhill,J., Dougan,G., James,K.D., Thomson,N.R., Pickard,D., Wain,J., Churcher,C., Mungall,K.L., Bentley,S.D., Holden,M.T., Sebaihia,M., Baker,S., Basham,D., Brooks,K., Chillingworth,T., Connerton,P., Cronin,A., Davis,P., Davies,R.M., Dowd,L., White,N., , "Direct Submission", Submitted (10-SEP-2013) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA.


DNA sequence : 
ATGCCAACATCTTGGTCAGGCTATCTGGATGAAGTTTCAGCAAAATTTGATAAGGGCGTTGATAATCTACAAACGCAGGT
AACAGAGGCGCTGGATAAATTAGCAGCAAAACCCTCCGATCCGGCGCTACTGGCGGCGTATCAGAGTAAGCTCTCGGAAT
ATAACTTGTACCGTAACGCGCAATCGAACACGGTAAAAGTCTTTAAGGATATTGATGCTGCCATTATTCAGAACTTCCGT
TAA

Protein sequence : 
MPTSWSGYLDEVSAKFDKGVDNLQTQVTEALDKLAAKPSDPALLAAYQSKLSEYNLYRNAQSNTVKVFKDIDAAIIQNFR