PAI Gene Information


Name : orgAa
Accession : NP_457264.1
PAI name : SPI-1
PAI accession : NC_003198_P5
Strain : Salmonella enterica RSK2980
Virulence or Resistance: Virulence
Product : cell invasion protein
Function : -
Note : Similar to Salmonella typhimurium oxygen-regulated invasion protein OrgA SW:ORGA_SALTY (P40823) (412 aa) fasta scores: E(): 0, 94.7% id in 189 aa, and to Escherichia coli orf_f141 TR:Q46795 (EMBL:U28375) (141 aa) fasta scores: E(): 0.00011, 26.2% id in 13
Homologs in the searched genomes :   42 hits    ( 42 protein-level )  
Publication :
    -Parkhill,J., "Direct Submission", Submitted (25-OCT-2001) Submitted on behalf of the Salmonalla sequencing team, Sanger Centre, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK.

    -Parkhill,J., Dougan,G., James,K.D., Thomson,N.R., Pickard,D., Wain,J., Churcher,C., Mungall,K.L., Bentley,S.D., Holden,M.T., Sebaihia,M., Baker,S., Basham,D., Brooks,K., Chillingworth,T., Connerton,P., Cronin,A., Davis,P., Davies,R.M., Dowd,L., White,N., , "Complete genome sequence of a multiple drug resistant Salmonella enterica serovar Typhi CT18", Nature 413 (6858), 848-852 (2001) PUBMED 11677608.

    -Parkhill,J., Dougan,G., James,K.D., Thomson,N.R., Pickard,D., Wain,J., Churcher,C., Mungall,K.L., Bentley,S.D., Holden,M.T., Sebaihia,M., Baker,S., Basham,D., Brooks,K., Chillingworth,T., Connerton,P., Cronin,A., Davis,P., Davies,R.M., Dowd,L., White,N., , "Direct Submission", Submitted (10-SEP-2013) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA.


DNA sequence : 
ATGAATAGGCAGCCATTACCCATTATCTGGCAAAGAATCATTTTTGATCCGTTATCGTATATCCATCCTCAGCGGTTGCA
GATAGCGCCGGAAATGATTGTCAGACCCGCCGCCAGGGCGGCGGCAAATGAGTTAATACTGGCGACATGGCGGCTTAAGA
ACGGAGAAAAGGAGTGTATTCAAAACTCACTGACGCAGCTGTGGCTGCGTCAGTGGCGCCGACTGCCGCAAGTAGCGTAT
TTACTCGGTTGCCATAAACTGAGAGCCGATCTGGCAAGGCAGGGAGCCTTGCTTGGCCTGCCGGATTGGGCGCAAGCATT
TTTGGCAATGCATCAGGGAACAAGTTTATCCGTTTGCAATAAGGCGCCGAATCACAGGTTTTTACTTAGCGTCGGGTATG
CACAGTTAAATGCCCTGAATGAATTTTTACCTGAATCTTTAGCACAGCGTTTTCCTTTGCTTTTTCCTCCATTTATTGAG
GAGGCATTGAAGCAGGATGCTGTAGAAATGTCAATTTTGCTACTGGCCTTACAATATGCTCAAAAATATCCCAATTCCGT
CCCCGCTTTCGCCTGTTGA

Protein sequence : 
MNRQPLPIIWQRIIFDPLSYIHPQRLQIAPEMIVRPAARAAANELILATWRLKNGEKECIQNSLTQLWLRQWRRLPQVAY
LLGCHKLRADLARQGALLGLPDWAQAFLAMHQGTSLSVCNKAPNHRFLLSVGYAQLNALNEFLPESLAQRFPLLFPPFIE
EALKQDAVEMSILLLALQYAQKYPNSVPAFAC